BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0592 (PAB0592) DE:DNA HELICASE RELATED PROTEIN
(715 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||B75135 DNA helicase related protein PAB0592 - Pyrococcus ab... 1421 0.0
pir||E71073 hypothetical protein PH1280 - Pyrococcus horikoshii ... 1248 0.0
pir||T43854 helicase [imported] - Pyrococcus furiosus >gi|337450... 1118 0.0
gi|11500032 SKI2-family helicase [Archaeoglobus fulgidus] 516 e-145
gb|AAG20465.1| (AE005119) DNA repair protein; Rad24b [Halobacter... 468 e-131
gb|AAK42601.1| DNA helicase related protein [Sulfolobus solfatar... 449 e-125
pir||E72775 probable helicase APE0191 - Aeropyrum pernix (strain... 426 e-118
emb|CAC11964.1| (AL445065) DNA helicase related protein [Thermop... 400 e-110
pir||C69208 DNA helicase related protein - Methanobacterium ther... 316 4e-85
pir||C64440 DNA repair protein RAD24 homolog (intein-containing)... 297 2e-79
gb|AAG20341.1| (AE005107) pre-mRNA splicing helicase; Brr2 [Halo... 228 2e-58
pir||T13858 probable DNA-directed DNA polymerase (EC 2.7.7.7) I ... 203 4e-51
emb|CAA11679.1| (AJ223948) RNA helicase [Homo sapiens] 202 1e-50
emb|CAB87588.1| (AL121965) dJ161I14.1 (RNA helicase) [Homo sapiens] 201 2e-50
gb|AAF50481.1| (AE003556) CG7972 gene product [Drosophila melano... 200 4e-50
pir||B75191 probable ATP-dependent RNA helicase PAB2313 - Pyroco... 198 3e-49
pir||A71223 hypothetical protein PH0044 - Pyrococcus horikoshii ... 191 2e-47
pir||H64474 hypothetical protein MJ1401 - Methanococcus jannasch... 188 2e-46
gi|6321710 Ygr271wp [Saccharomyces cerevisiae] >gi|1723776|sp|P5... 185 2e-45
dbj|BAB10376.1| (AB006696) RNA helicase [Arabidopsis thaliana] 185 2e-45
gb|AAC49699.1| (U35242) G9365 ORF [Saccharomyces cerevisiae] 185 2e-45
dbj|BAB14906.1| (AK024391) unnamed protein product [Homo sapiens] 184 2e-45
dbj|BAA34508.1| (AB018331) KIAA0788 protein [Homo sapiens] 184 3e-45
emb|CAB60351.1| (AL110485) contains similarity to Pfam domain: P... 182 2e-44
gi|6321020 putative ATP-dependent RNA helicase; Brr2p [Saccharom... 181 2e-44
sp|P51979|HFM1_YEAST HFM1 PROTEIN >gi|780546|gb|AAA93159.1| (U22... 179 8e-44
gb|AAF55204.1| (AE003709) CG5205 gene product [Drosophila melano... 179 1e-43
pir||T27149 hypothetical protein Y54E2A.6 - Caenorhabditis elega... 179 1e-43
pir||T39411 RNA helicase - fission yeast (Schizosaccharomyces po... 178 1e-43
pir||S61610 HFM1 protein - yeast (Saccharomyces cerevisiae) >gi|... 176 5e-43
emb|CAA94089.1| (Z70200) U5 snRNP-specific 200kD protein [Homo s... 176 5e-43
gi|9755332 C4 zinc finger DNA-binding protein of low sequence sp... 176 5e-43
pir||T00936 ATP-dependent RNA helicase homolog T24P15.18 - Arabi... 176 9e-43
gb|AAD30595.1|AC007369_5 (AC007369) Putative RNA helicase [Arabi... 175 2e-42
dbj|BAB14698.1| (AK023840) unnamed protein product [Homo sapiens] 174 3e-42
pir||T39188 probable U5 snRNP-specific 200kd protein - fission y... 173 5e-42
gb|AAF49564.2| (AE003529) CG5931 gene product [Drosophila melano... 171 3e-41
pir||T04456 hypothetical protein F4D11.100 - Arabidopsis thalian... 168 2e-40
pir||C69187 conserved hypothetical protein MTH656 - Methanobacte... 162 9e-39
pir||H70414 conserved hypothetical protein aq_1328 - Aquifex aeo... 153 4e-36
gb|AAG20308.1| (AE005105) DNA repair protein; Rad24a [Halobacter... 153 6e-36
pir||T41378 probable helicase - fission yeast (Schizosaccharomyc... 143 5e-33
gi|9631809 contains ATP-GTP binding motif; similar to Saccharomy... 143 5e-33
dbj|BAB02697.1| (AB018114) helicase-like protein [Arabidopsis th... 142 1e-32
sp|O14232|YDVG_SCHPO PUTATIVE HELICASE C6F12.16C IN CHROMOSOME I... 141 3e-32
emb|CAC11967.1| (AL445065) Large helicase related protein [Therm... 140 6e-32
gb|AAC67203.1| (AC005171) unknown protein [Arabidopsis thaliana] 137 5e-31
gb|AAD38613.1|AF145638_1 (AF145638) l.2.35Df [Drosophila melanog... 135 2e-30
gi|6322411 RNA helicase; Mtr4p [Saccharomyces cerevisiae] >gi|13... 134 2e-30
gb|AAD39319.1|AC007258_8 (AC007258) Very similar to helicases [A... 134 4e-30
sp|P42285|Y052_HUMAN HYPOTHETICAL PROTEIN KIAA0052 131 3e-29
dbj|BAA06124.2| (D29641) KIAA0052 protein [Homo sapiens] 131 3e-29
sp|O13799|YE02_SCHPO PUTATIVE HELICASE C17H9.02 IN CHROMOSOME I ... 129 1e-28
gb|AAG19610.1| (AE005050) ATP-dependent helicase; HelA [Halobact... 127 3e-28
sp|Q23223|YH2O_CAEEL PUTATIVE HELICASE W08D2.7 IN CHROMOSOME IV ... 126 7e-28
sp|Q10701|HELY_MYCTU PUTATIVE HELICASE HELY >gi|7478108|pir||G70... 124 3e-27
emb|CAA22943.1| (AL035310) putative helicase [Mycobacterium leprae] 123 8e-27
gi|10946650 similar to SKI2W protein [Mus musculus] >gi|2944423|... 122 1e-26
gi|11498749 large helicase-related protein (lhr-1) [Archaeoglobu... 122 1e-26
pir||S56752 helicase SKI2W - human >gi|4379045|emb|CAA88733.1| (... 121 2e-26
gi|11417770 superkiller viralicidic activity 2 (S. cerevisiae ho... 120 4e-26
gi|5902086 superkiller viralicidic activity 2 (S. cerevisiae hom... 120 4e-26
emb|CAB88936.1| (AL353863) putative helicase [Streptomyces coeli... 120 4e-26
sp|Q15477|SKIW_HUMAN HELICASE SKI2W (HELICASE-LIKE PROTEIN) (HLP) 120 4e-26
gb|AAC78607.1| (AF059675) putative RNA helicase Ski2w [Homo sapi... 120 4e-26
emb|CAB89307.1| (AL049547) dJ34F7.7 (superkiller viralicidic act... 120 4e-26
gb|AAB52523.1| (U09877) helicase-like protein [Homo sapiens] 120 5e-26
pir||B75127 large helicase-related protein (lhr-1) PAB1817 - Pyr... 117 5e-25
pir||C71004 probable ATP-dependent helicase - Pyrococcus horikos... 116 6e-25
pir||T34471 hypothetical protein W03A3.3 - Caenorhabditis elegan... 116 8e-25
gb|AAF59592.1| (AC024820) contains similarity to TR:O18475 [Caen... 115 2e-24
gb|AAF24214.1|AF165818_7 (AF165818) putative helicase-like prote... 115 2e-24
gi|11499982 ATP-dependent RNA helicase, putative [Archaeoglobus ... 110 5e-23
sp|P50830|YPRA_BACSU HYPOTHETICAL HELICASE IN PONA-COTD INTERGEN... 110 5e-23
emb|CAB58415.1| (AL122012) possible MUS308 homolog [Leishmania m... 109 8e-23
pir||T17399 probable DEAH ATP-dependent helicase vrlS - Dichelob... 107 5e-22
pir||A69140 ATP-dependent helicase - Methanobacterium thermoauto... 103 8e-21
pir||S76892 hypothetical protein - Synechocystis sp. (strain PCC... 101 2e-20
gb|AAK40467.1| ATP-dependent helicase [Sulfolobus solfataricus] 101 4e-20
sp|P95949|HELX_SULSO PUTATIVE ATP-DEPENDENT HELICASE C04010 >gi|... 101 4e-20
pir||D75091 large helicase-related protein (lhr-2) PAB0744 - Pyr... 100 7e-20
emb|CAB59484.1| (AL132648) putative helicase [Streptomyces coeli... 99 1e-19
gb|AAK41239.1| ATP-dependent helicase [Sulfolobus solfataricus] 99 2e-19
pir||T35049 probable ATP-dependent helicase - Streptomyces coeli... 99 2e-19
pir||T20487 hypothetical protein F01G4.3 - Caenorhabditis elegan... 99 2e-19
pir||A70982 probable ATP-dependent helicase lhr - Mycobacterium ... 98 3e-19
dbj|BAB05483.1| (AP001513) ATP-dependent RNA helicase [Bacillus ... 97 8e-19
gb|AAA35049.1| (L13469) antiviral protein [Saccharomyces cerevis... 96 1e-18
gi|6323430 antiviral protein, putative helicase; Ski2p [Saccharo... 96 1e-18
pir||T35694 ATP dependent DNA helicase - Streptomyces coelicolor... 95 2e-18
pir||G71051 probable ATP-dependent helicase LHR - Pyrococcus hor... 95 2e-18
gb|AAK40384.1| ATP-dependent helicase [Sulfolobus solfataricus] 94 5e-18
pir||T45632 helicase homolog F13I12.10 - Arabidopsis thaliana >g... 94 7e-18
pir||F69164 ATP-dependent RNA helicase homolog MTH492 - Methanob... 93 1e-17
gi|11500031 large helicase-related protein (lhr-2) [Archaeoglobu... 92 2e-17
gb|AAD40191.1| (AF085356) putative RNA helicase [Homo sapiens] 90 6e-17
emb|CAB60375.1| (AL110485) contains similarity to Pfam domain: P... 89 2e-16
emb|CAA11251.1| (AJ223310) helicase [Streptomyces avermitilis] >... 88 4e-16
pir||A56003 nucleolar protein SKI2 homolog - human 86 1e-15
pir||F83237 probable ATP-dependent DNA helicase PA3272 [imported... 83 1e-14
gb|AAB61106.1| (AC002062) Similar to Synechocystis antiviral pro... 75 3e-12
pir||T50247 probable helicase [imported] - fission yeast (Schiz... 75 3e-12
pir||T38420 probable dna helicases - fission yeast (Schizosaccha... 75 4e-12
>pir||B75135 DNA helicase related protein PAB0592 - Pyrococcus abyssi (strain
Orsay) >gi|5458306|emb|CAB49795.1| (AJ248285) DNA
HELICASE RELATED PROTEIN [Pyrococcus abyssi]
Length = 715
Score = 1421 bits (3637), Expect = 0.0
Identities = 715/715 (100%), Positives = 715/715 (100%)
Query: 1 MKVGELNVSEKIKEILRERGIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAI 60
MKVGELNVSEKIKEILRERGIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAI
Sbjct: 1 MKVGELNVSEKIKEILRERGIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAI 60
Query: 61 ANKLLEEGGKAVYIVPLKALAEEKFREFKDWERLGLKVAMATGDYDSKDEWLGKYDIIIA 120
ANKLLEEGGKAVYIVPLKALAEEKFREFKDWERLGLKVAMATGDYDSKDEWLGKYDIIIA
Sbjct: 61 ANKLLEEGGKAVYIVPLKALAEEKFREFKDWERLGLKVAMATGDYDSKDEWLGKYDIIIA 120
Query: 121 TAEKFDSLLRHGSSWIRDVKMLVIDEIHLIGSRDRGATLEFIITQMLGRAQIIGLSATIG 180
TAEKFDSLLRHGSSWIRDVKMLVIDEIHLIGSRDRGATLEFIITQMLGRAQIIGLSATIG
Sbjct: 121 TAEKFDSLLRHGSSWIRDVKMLVIDEIHLIGSRDRGATLEFIITQMLGRAQIIGLSATIG 180
Query: 181 NPEELAEWLNAKLIRSDWRPVKLRKGVFYQGFVFWEDGGSERYNSWEELVYDAVKKGKGA 240
NPEELAEWLNAKLIRSDWRPVKLRKGVFYQGFVFWEDGGSERYNSWEELVYDAVKKGKGA
Sbjct: 181 NPEELAEWLNAKLIRSDWRPVKLRKGVFYQGFVFWEDGGSERYNSWEELVYDAVKKGKGA 240
Query: 241 LVFVNMRRKAEKTALELAKKVKNYLDRKELRELRELAESLEENPTNEKLAKALLSGVAFH 300
LVFVNMRRKAEKTALELAKKVKNYLDRKELRELRELAESLEENPTNEKLAKALLSGVAFH
Sbjct: 241 LVFVNMRRKAEKTALELAKKVKNYLDRKELRELRELAESLEENPTNEKLAKALLSGVAFH 300
Query: 301 HAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWRYSEFGMERIPVL 360
HAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWRYSEFGMERIPVL
Sbjct: 301 HAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWRYSEFGMERIPVL 360
Query: 361 EVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKGKPEKLFSQLSNESILRSQILA 420
EVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKGKPEKLFSQLSNESILRSQILA
Sbjct: 361 EVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKGKPEKLFSQLSNESILRSQILA 420
Query: 421 LIATFGYSEFKEIYDFLERTFYAHQGKDPYMLEEKIRRIIYFLLENEFIEVTLEDEIKPL 480
LIATFGYSEFKEIYDFLERTFYAHQGKDPYMLEEKIRRIIYFLLENEFIEVTLEDEIKPL
Sbjct: 421 LIATFGYSEFKEIYDFLERTFYAHQGKDPYMLEEKIRRIIYFLLENEFIEVTLEDEIKPL 480
Query: 481 PLGVRTTKLYIDPMTAKIFKDTLPRIEKNPNPLGIFHMISLAPDLTPLSYSKRETSMLED 540
PLGVRTTKLYIDPMTAKIFKDTLPRIEKNPNPLGIFHMISLAPDLTPLSYSKRETSMLED
Sbjct: 481 PLGVRTTKLYIDPMTAKIFKDTLPRIEKNPNPLGIFHMISLAPDLTPLSYSKRETSMLED 540
Query: 541 EYYSLMDRLYFELDYENERKFFRAFKTALVLNAWINEVPEGEIVERFNVEPGDIYRIVET 600
EYYSLMDRLYFELDYENERKFFRAFKTALVLNAWINEVPEGEIVERFNVEPGDIYRIVET
Sbjct: 541 EYYSLMDRLYFELDYENERKFFRAFKTALVLNAWINEVPEGEIVERFNVEPGDIYRIVET 600
Query: 601 AEWLIYSLGEIAKVLEASQEVVDYVNTLRLRVKHGIREELIPLMELPMVGRKRARALYNA 660
AEWLIYSLGEIAKVLEASQEVVDYVNTLRLRVKHGIREELIPLMELPMVGRKRARALYNA
Sbjct: 601 AEWLIYSLGEIAKVLEASQEVVDYVNTLRLRVKHGIREELIPLMELPMVGRKRARALYNA 660
Query: 661 GFKDLESIRNAKPSELLRIEGIGAKIVEGIFKYLGKEVKITERPRKGTLDYFLNP 715
GFKDLESIRNAKPSELLRIEGIGAKIVEGIFKYLGKEVKITERPRKGTLDYFLNP
Sbjct: 661 GFKDLESIRNAKPSELLRIEGIGAKIVEGIFKYLGKEVKITERPRKGTLDYFLNP 715
>pir||E71073 hypothetical protein PH1280 - Pyrococcus horikoshii
>gi|3257700|dbj|BAA30383.1| (AP000005) 715aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 715
Score = 1248 bits (3195), Expect = 0.0
Identities = 602/715 (84%), Positives = 674/715 (94%)
Query: 1 MKVGELNVSEKIKEILRERGIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAI 60
MKV EL + E+IKE+L++RGI ELYPPQAEALTSG+L+GEN L+AIPTASGKTLIAEIAI
Sbjct: 1 MKVEELRIDERIKEVLKKRGISELYPPQAEALTSGILKGENALIAIPTASGKTLIAEIAI 60
Query: 61 ANKLLEEGGKAVYIVPLKALAEEKFREFKDWERLGLKVAMATGDYDSKDEWLGKYDIIIA 120
N+LL+EGGKAVY+VPLKALAEEKF+EFKDWE LGLKVAMATGDYDSKDEWLG YDIIIA
Sbjct: 61 VNRLLKEGGKAVYLVPLKALAEEKFKEFKDWEELGLKVAMATGDYDSKDEWLGGYDIIIA 120
Query: 121 TAEKFDSLLRHGSSWIRDVKMLVIDEIHLIGSRDRGATLEFIITQMLGRAQIIGLSATIG 180
TAEKFDSLLRHGSSWIR+VK+LV+DEIHLIGSRDRGATLEFIITQML RAQIIGLSATIG
Sbjct: 121 TAEKFDSLLRHGSSWIRNVKVLVVDEIHLIGSRDRGATLEFIITQMLNRAQIIGLSATIG 180
Query: 181 NPEELAEWLNAKLIRSDWRPVKLRKGVFYQGFVFWEDGGSERYNSWEELVYDAVKKGKGA 240
NPEELAEWLNAKLI+SDWRPVKLR+GVFYQGFVFWEDG +E++NSWEELVYDA+K+ KG+
Sbjct: 181 NPEELAEWLNAKLIKSDWRPVKLRRGVFYQGFVFWEDGKTEKFNSWEELVYDAIKRSKGS 240
Query: 241 LVFVNMRRKAEKTALELAKKVKNYLDRKELRELRELAESLEENPTNEKLAKALLSGVAFH 300
LVFVNMRRKAEKTALEL+KK++N+L +KELREL+ELAESLEENPTNEKLAKAL GVAFH
Sbjct: 241 LVFVNMRRKAEKTALELSKKIRNFLTKKELRELKELAESLEENPTNEKLAKALQGGVAFH 300
Query: 301 HAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWRYSEFGMERIPVL 360
HAGLGR+ERVLVE+NF+KGLIKVVVATPTLSAGINTPAFRVI+RDTWRYSEFGMERIP+L
Sbjct: 301 HAGLGREERVLVEENFKKGLIKVVVATPTLSAGINTPAFRVIVRDTWRYSEFGMERIPIL 360
Query: 361 EVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKGKPEKLFSQLSNESILRSQILA 420
E+QQMMGRAGRP+YDEVGEAIIVSTTEEPS V++ YIKGKPEKLFSQLSNESILR QILA
Sbjct: 361 EIQQMMGRAGRPKYDEVGEAIIVSTTEEPSTVMERYIKGKPEKLFSQLSNESILRGQILA 420
Query: 421 LIATFGYSEFKEIYDFLERTFYAHQGKDPYMLEEKIRRIIYFLLENEFIEVTLEDEIKPL 480
LIATF +S F+EIYDFLERTFYA+QGKDPY LE++IR I+YFLLENEFIE+TL+DEIK L
Sbjct: 421 LIATFNFSSFREIYDFLERTFYAYQGKDPYTLEDRIRDIVYFLLENEFIEITLDDEIKAL 480
Query: 481 PLGVRTTKLYIDPMTAKIFKDTLPRIEKNPNPLGIFHMISLAPDLTPLSYSKRETSMLED 540
PLG+RT KLYIDPMTAKIFKDTLP+IEK+PNPLGI H+ISL PDL PL Y K+E MLED
Sbjct: 481 PLGIRTAKLYIDPMTAKIFKDTLPKIEKDPNPLGILHVISLTPDLIPLPYGKKELPMLED 540
Query: 541 EYYSLMDRLYFELDYENERKFFRAFKTALVLNAWINEVPEGEIVERFNVEPGDIYRIVET 600
EYYS DRLYFELD+E+ERKF RAFKTALVLNAWINEVPEGEIVE+FNVEPGDIYRIVET
Sbjct: 541 EYYSFKDRLYFELDWEDERKFLRAFKTALVLNAWINEVPEGEIVEKFNVEPGDIYRIVET 600
Query: 601 AEWLIYSLGEIAKVLEASQEVVDYVNTLRLRVKHGIREELIPLMELPMVGRKRARALYNA 660
AEWL+YSL EIAK LE SQ+V++Y+ TLR+RVKHGIREELIPLMELPM+GRKRARALYNA
Sbjct: 601 AEWLVYSLKEIAKTLEYSQDVINYLETLRVRVKHGIREELIPLMELPMIGRKRARALYNA 660
Query: 661 GFKDLESIRNAKPSELLRIEGIGAKIVEGIFKYLGKEVKITERPRKGTLDYFLNP 715
GF+DLESI+NA+P+ELL +EGIGAKIVE I K+LG+EVKI ++PRKGTLDY+L+P
Sbjct: 661 GFRDLESIKNARPAELLEVEGIGAKIVEAILKHLGREVKIVQKPRKGTLDYYLHP 715
>pir||T43854 helicase [imported] - Pyrococcus furiosus
>gi|3374506|dbj|BAA32016.1| (AB016521) helicase
[Pyrococcus furiosus]
Length = 720
Score = 1118 bits (2860), Expect = 0.0
Identities = 545/719 (75%), Positives = 633/719 (87%), Gaps = 7/719 (0%)
Query: 1 MKVGELNVSEKIKEILRERGIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAI 60
M+V EL V E+IK L+ERGIE YPPQAEAL SG+LEG+N L++IPTASGKTLIAEIA+
Sbjct: 1 MRVDELRVDERIKSTLKERGIESFYPPQAEALKSGILEGKNALISIPTASGKTLIAEIAM 60
Query: 61 ANKLLEEGGKAVYIVPLKALAEEKFREFKDWERLGLKVAMATGDYDSKDEWLGKYDIIIA 120
+++L +GGKAVYIVPLKALAEEKF+EF+DWE++GL+VAMATGDYDSKDEWLGKYDIIIA
Sbjct: 61 VHRILTQGGKAVYIVPLKALAEEKFQEFQDWEKIGLRVAMATGDYDSKDEWLGKYDIIIA 120
Query: 121 TAEKFDSLLRHGSSWIRDVKMLVIDEIHLIGSRDRGATLEFIITQMLGRAQIIGLSATIG 180
TAEKFDSLLRHGSSWI+DVK+LV DEIHLIGSRDRGATLE I+ MLG+AQIIGLSATIG
Sbjct: 121 TAEKFDSLLRHGSSWIKDVKILVADEIHLIGSRDRGATLEVILAHMLGKAQIIGLSATIG 180
Query: 181 NPEELAEWLNAKLIRSDWRPVKLRKGVFYQGFVFWEDGGSERYNSWEELVYDAVKKGKGA 240
NPEELAEWLNA+LI SDWRPVKLR+GVFYQGFV WEDG +R++SWEELVYDA++K KGA
Sbjct: 181 NPEELAEWLNAELIVSDWRPVKLRRGVFYQGFVTWEDGSIDRFSSWEELVYDAIRKKKGA 240
Query: 241 LVFVNMRRKAEKTALELAKKVKNYLDRKELRELRELAESLEENPTNEKLAKALLSGVAFH 300
L+FVNMRRKAE+ ALEL+KKVK+ L + E+R L ELA+SLEENPTNEKLAKA+ GVAFH
Sbjct: 241 LIFVNMRRKAERVALELSKKVKSLLTKPEIRALNELADSLEENPTNEKLAKAIRGGVAFH 300
Query: 301 HAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWRYSEFGMERIPVL 360
HAGLGRDERVLVE+NFRKG+IK VVATPTLSAGINTPAFRVIIRD WRYS+FGMERIP++
Sbjct: 301 HAGLGRDERVLVEENFRKGIIKAVVATPTLSAGINTPAFRVIIRDIWRYSDFGMERIPII 360
Query: 361 EVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKGKPEKLFSQLSNESILRSQILA 420
EV QM+GRAGRP+YDEVGE IIVST+++P V++HYI GKPEKLFSQLSNES LRSQ+LA
Sbjct: 361 EVHQMLGRAGRPKYDEVGEGIIVSTSDDPREVMNHYIFGKPEKLFSQLSNESNLRSQVLA 420
Query: 421 LIATFGYSEFKEIYDFLERTFYAHQGKDPYMLEEKIRRIIYFLLENEFIEVTLEDEIKPL 480
LIATFGYS +EI F+ TFYA+Q KD Y LEEKIR I+YFLLENEFIE++LED+I+PL
Sbjct: 421 LIATFGYSTVEEILKFISNTFYAYQRKDTYSLEEKIRNILYFLLENEFIEISLEDKIRPL 480
Query: 481 PLGVRTTKLYIDPMTAKIFKDTLPRIEKNPNPLGIFHMISLAPDLTPLSYSKRETSMLED 540
LG+RT KLYIDP TAK+FKD + + K+PNP+GIFH+ISL PD+TP +YSKRE LE+
Sbjct: 481 SLGIRTAKLYIDPYTAKMFKDKMEEVVKDPNPIGIFHLISLTPDITPFNYSKREFERLEE 540
Query: 541 EYYSLMDRLYFELDYEN------ERKFFRAFKTALVLNAWINEVPEGEIVERFNVEPGDI 594
EYY DRLYF+ Y + ERKFFRAFKTALVL AWINEVPEGEIVE+++VEPGDI
Sbjct: 541 EYYEFKDRLYFDDPYISGYDPYLERKFFRAFKTALVLLAWINEVPEGEIVEKYSVEPGDI 600
Query: 595 YRIVETAEWLIYSLGEIAKVLEASQEVVDYVNTLRLRVKHGIREELIPLMELPMVGRKRA 654
YRIVETAEWL+YSL EIAKVL A E+VDY+ TLR+RVK+GIREELIPLM+LP+VGR+RA
Sbjct: 601 YRIVETAEWLVYSLKEIAKVLGA-YEIVDYLETLRVRVKYGIREELIPLMQLPLVGRRRA 659
Query: 655 RALYNAGFKDLESIRNAKPSELLRIEGIGAKIVEGIFKYLGKEVKITERPRKGTLDYFL 713
RALYN+GF+ +E I A+P ELL+IEGIG K VE IFK+LGK VKI+E+PRK TLDYFL
Sbjct: 660 RALYNSGFRSIEDISQARPEELLKIEGIGVKTVEAIFKFLGKNVKISEKPRKSTLDYFL 718
>gi|11500032 SKI2-family helicase [Archaeoglobus fulgidus]
Length = 691
Score = 516 bits (1314), Expect = e-145
Identities = 312/704 (44%), Positives = 446/704 (63%), Gaps = 36/704 (5%)
Query: 1 MKVGEL--NVSEKIKEILRERGIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEI 58
MKV EL ++S IL+E GIEEL+PPQAEA+ V G+NLL+A+PTA+GKTL+AE+
Sbjct: 1 MKVEELAESISSYAVGILKEEGIEELFPPQAEAVEK-VFSGKNLLLAMPTAAGKTLLAEM 59
Query: 59 AIANKLLEEGGKAVYIVPLKALAEEKFREFKDWERLGLKVAMATGDYDSKDEWLGKYDII 118
A+ + ++ GGK++Y+VPL+ALA EK+ FK WE++GL++ ++TGDY+S+DE LG DII
Sbjct: 60 AMVREAIK-GGKSLYVVPLRALAGEKYESFKKWEKIGLRIGISTGDYESRDEHLGDCDII 118
Query: 119 IATAEKFDSLLRHGSSWIRDVKMLVIDEIHLIGSRDRGATLEFIITQM--LGRA-QIIGL 175
+ T+EK DSL+R+ +SWI+ V LV+DEIHL+ S RGATLE ++T+M + +A ++IGL
Sbjct: 119 VTTSEKADSLIRNRASWIKAVSCLVVDEIHLLDSEKRGATLEILVTKMRRMNKALRVIGL 178
Query: 176 SATIGNPEELAEWLNAKLIRSDWRPVKLRKGVFYQGFVFWEDG--GSERYNSWEELVYDA 233
SAT N E+AEWL+A SDWRPV L +GV +G + DG + R +EELV +
Sbjct: 179 SATAPNVTEIAEWLDADYYVSDWRPVPLVEGVLCEGTLELFDGAFSTSRRVKFEELVEEC 238
Query: 234 VKKGKGALVFVNMRRKAEKTALELAKKVKNYLDRKELRELRELAESLEEN--PTNEKLAK 291
V + G LVF + RR AEKTA++L+ Y++ + L + LEEN + KLA+
Sbjct: 239 VAENGGVLVFESTRRGAEKTAVKLSAITAKYVENEGLEK-----AILEENEGEMSRKLAE 293
Query: 292 ALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWRYSE 351
+ G AFHHAGL +R +VED FR+G IKVVVATPTL+AG+N PA RVI+R +R+
Sbjct: 294 CVRKGAAFHHAGLLNGQRRVVEDAFRRGNIKVVVATPTLAAGVNLPARRVIVRSLYRFDG 353
Query: 352 FGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKGKPEKLFSQLSNE 411
+ +RI V E +QM GRAGRP DE GEAII+ + + + YI G+PE++ S+L E
Sbjct: 354 YS-KRIKVSEYKQMAGRAGRPGMDERGEAIIIVGKRDREIAVKRYIFGEPERITSKLGVE 412
Query: 412 SILRSQILALIATFGYSEFKEIYDFLERTFYAHQGKD--PYMLEEKIRRIIYFLLENEFI 469
+ LR L++I +E+ DF TF+ Q + Y LE +R+ LEN +
Sbjct: 413 THLRFHSLSIICDGYAKTLEELEDFFADTFFFKQNEISLSYELERVVRQ-----LEN-WG 466
Query: 470 EVTLEDEIKPLPLGVRTTKLYIDPMTAKIFKDTLPRIEKNPNPLGIFHMISLAPDLTPLS 529
V + + P LG ++LYIDP+T IF D L R+E + +G H+I PD+ L+
Sbjct: 467 MVVEDHHLAPTKLGSLVSRLYIDPLTGFIFHDVLSRMEL--SDIGALHLICRTPDMERLT 524
Query: 530 YSKRETSMLEDEYYSLMDRL-YFELDYENERKFFRA-FKTALVLNAWINEVPEGEIVERF 587
K + S +E+E + L L Y+ D+ E +F + KTAL L WI E E EI ++
Sbjct: 525 VRKTD-SWVEEEAFRLRKELSYYPSDFSVEYDWFLSEVKTALCLKDWIEEKDEDEICAKY 583
Query: 588 NVEPGDIYRIVETAEWLIYSLGEIAKVLEASQEVVDYVNTLRLRVKHGIREELIPLMELP 647
+ PGD+ RIVETAEWL ++ IA+ + + V+ L R+KHG++EEL+ L+ +
Sbjct: 584 GIAPGDLRRIVETAEWLSNAMNRIAEEVGNTS-----VSGLTERIKHGVKEELLELVRIR 638
Query: 648 MVGRKRARALYNAGFKDLESI-RNAKPSELLRIEGIGAKIVEGI 690
+GR RAR LYNAG ++ E I R+ + L GI ++VEGI
Sbjct: 639 HIGRVRARKLYNAGIRNAEDIVRHREKVASLIGRGIAERVVEGI 682
>gb|AAG20465.1| (AE005119) DNA repair protein; Rad24b [Halobacterium sp. NRC-1]
Length = 783
Score = 468 bits (1192), Expect = e-131
Identities = 286/730 (39%), Positives = 408/730 (55%), Gaps = 57/730 (7%)
Query: 20 GIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLEEG--------GKA 71
G+EELYPPQAEA+ GV EG NL+ ++PTASGKTLIA++A+ + + E G G A
Sbjct: 21 GVEELYPPQAEAVERGVTEGANLVASVPTASGKTLIAQLAMLSAIAEGGDSPTFSGDGTA 80
Query: 72 VYIVPLKALAEEKFREFKDWERLGLKVAMATGDYDSKDEWLGKYDIIIATAEKFDSLLRH 131
+YIVPL+ALA EK +EF+ +ER GL V ++TG+Y+ L DI++AT+EK DSL+R+
Sbjct: 81 LYIVPLRALAGEKAQEFEAFERFGLSVGVSTGNYERDGARLADNDIVVATSEKVDSLVRN 140
Query: 132 GSSWIRDVKMLVIDEIHLIGSRDRGATLEFIIT---QMLGRAQIIGLSATIGNPEELAEW 188
G+ WI D+ +V DE+HL+ RG TLE + Q + Q++ LSAT+GN ELA W
Sbjct: 141 GAGWIDDLSCVVADEVHLVDDDHRGPTLEVTLAKLRQQVADLQVVALSATVGNAGELAAW 200
Query: 189 LNAKLIRSDWRPVKLRKGVFYQGFVFWEDGGSERY-----NSWEELVYDAVKKGKGALVF 243
L+A+L+ SDWRP++LR GV Y + ++DG + +V D + LVF
Sbjct: 201 LDAELVDSDWRPIELRTGVHYGQSLHYDDGTQAELSVGSGSQTAAVVADTLADDGSTLVF 260
Query: 244 VNMRRKAEKTALELAKKVKNYLDRKELRELRELA---ESLEENPTNEKLAKALLSGVAFH 300
VN RR AE +A LA N L E L ++A + + T+++LA A+ SG AFH
Sbjct: 261 VNSRRNAEASARRLADVTGNALSSAERERLADIAAEIRGVSDTETSDELADAVASGAAFH 320
Query: 301 HAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWRY--SEFGMERIP 358
HAGL R+ R LVE+ FR L+K V ATPTL+AG+NTPA RV++RD RY + GM+ +
Sbjct: 321 HAGLAREHRELVEEAFRDRLVKAVSATPTLAAGVNTPARRVVVRDWQRYDGTAGGMQPLD 380
Query: 359 VLEVQQMMGRAGRPRYDEVGEAIIVSTT-EEPSLVIDHYIKGKPEKLFSQLSNESILRSQ 417
VLEV QM GRAGRP D GEA++++ + +E + D Y+ PE + S+L+ E LR+
Sbjct: 381 VLEVHQMFGRAGRPGLDPYGEAVLLANSHDELEELFDRYVYADPEPVRSKLAAEPALRTH 440
Query: 418 ILALIATFGYSEFKEIYDFLERTFYAHQGKDPYMLEEKIRRIIYFLLENEFIEVTLEDEI 477
+LA IAT + +++FL T YA Q D L ++ +L N F+E +
Sbjct: 441 VLAAIATGFTTTEDGLHEFLGGTLYATQTDDTGRLRSVTGDVLRYLDRNGFVERD-GAAL 499
Query: 478 KPLPLGVRTTKLYIDPMTAKIFKDTLPRIEKN---------------------------- 509
+ G ++LY+DPM+A D L ++
Sbjct: 500 RATATGQLVSRLYVDPMSAATIIDGLRDAARDATETDDEGAFRPASELGDDAALPADASV 559
Query: 510 -PNPLGIFHMISLAPDLTPLSYSKRETSMLEDEYYSLMDRLYFELDYENERKF---FRAF 565
P PLG++H++S PD+ L + + Y D L E + +F A
Sbjct: 560 EPTPLGLYHLVSRTPDMYELYLRSGDREQYTEVAYEHEDELLGATPREEQAEFEDWLSAL 619
Query: 566 KTALVLNAWINEVPEGEIVERFNVEPGDIYRIVETAEWLIYSLGEIAKVLEASQEVVDYV 625
KTA ++ W +E+ E I ER++V PGDI VETAEWL+ + +A L+ E V
Sbjct: 620 KTARLMADWASELDEERIAERYDVGPGDIRGKVETAEWLLNAAERLAGELDV--ECGPAV 677
Query: 626 NTLRLRVKHGIREELIPLMELPMVGRKRARALYNAGFKDLESIRNAKPSELLRIEGIGAK 685
R RV++G+REEL+ L + VGRKRAR LYNAG + +RNA +L A
Sbjct: 678 REARKRVQYGVREELLGLAGVRNVGRKRARRLYNAGVESRADLRNADKGVVLGAVRGRAA 737
Query: 686 IVEGIFKYLG 695
E I + +G
Sbjct: 738 TAERILETVG 747
>gb|AAK42601.1| DNA helicase related protein [Sulfolobus solfataricus]
Length = 715
Score = 449 bits (1143), Expect = e-125
Identities = 270/716 (37%), Positives = 410/716 (56%), Gaps = 30/716 (4%)
Query: 1 MKVGELNVSEKIKEILRERGIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAI 60
M + +L + + +I++ RGI++L PPQ EA+ G+L+G LL+ PT SGKTLIAE+ I
Sbjct: 8 MSIDDLKLPSNVIDIIKNRGIKKLNPPQTEAVKKGLLDGNRLLLTSPTGSGKTLIAEMGI 67
Query: 61 ANKLLEEGGKAVYIVPLKALAEEKFREFKDWERLGLKVAMATGDYDSKDEWLGKYDIIIA 120
+ LL+ GGKA+Y+ PL+AL EK+ FKDWE +G KVAM +GDYD+ D WL YDIII
Sbjct: 68 ISFLLKNGGKAIYVTPLRALTNEKYLTFKDWESIGFKVAMTSGDYDTDDAWLKNYDIIIT 127
Query: 121 TAEKFDSLLRHGSSWIRDVKMLVIDEIHLIGSRDRGATLEFIITQMLGRAQIIGLSATIG 180
T EK DSL RH W+ + V+DE+H + +RG +E +T R ++ LSATI
Sbjct: 128 TYEKLDSLWRHRPDWLNEANYFVLDELHYLNDPERGPVVE-SVTIRAKRRNLLALSATIS 186
Query: 181 NPEELAEWLNAKLIRSDWRPVKLRKGVFY------QGFVFWEDGGSERYNSWEELV---Y 231
N +++A+WL A+ + ++WRPV L +GV Y + + + D + + + + ++
Sbjct: 187 NYKQIAKWLGAEPVATNWRPVPLMEGVMYPERKKKEYTILFRDNTARKVHGDDAIIAYTL 246
Query: 232 DAVKKGKGALVFVNMRRKAEKTALELAKKVKNY--LDRKELRELRELAESLEENPTNEK- 288
D++ K LVF N R+ AE TAL++A + N+ LD K + E+ + + +EE ++EK
Sbjct: 247 DSLSKNGQVLVFRNSRKMAESTALKIANYM-NFVSLDEKAISEILKQLDDIEEGGSDEKE 305
Query: 289 LAKALLS-GVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTW 347
L K+L+S GVA+HHAGL + R ++E++FRK IKV+VATPTL+AG+N PA VII D +
Sbjct: 306 LLKSLISKGVAYHHAGLSKALRDIIEESFRKRKIKVIVATPTLAAGVNLPARTVIIGDIY 365
Query: 348 RYSEFGM---ERIPVLEVQQMMGRAGRPRYDEVGEAII-VSTTEEPSLVIDHYIKGKPEK 403
R++ + + IPV+E +QM GRAGRP +D++GE+II V E+ V YI E
Sbjct: 366 RFNRKIVGYYDEIPVMEYKQMSGRAGRPGFDQIGESIIVVRDKEDVDRVFKKYILSDVEP 425
Query: 404 LFSQLSNESILRSQILALIATFGYSEFKEIYDFLERTFYAHQGKDPYMLEEKIRRIIYFL 463
+ S+L +E + +L +++ G K++ F + A D Y R I +L
Sbjct: 426 IESKLGSERAFYTFLLGILSAEGSLSEKQLEAFAYESLLAKSVVDVY-----FDRAIRWL 480
Query: 464 LENEFIEVTLEDEIKPLPLGVRTTKLYIDPMTAKIFKDTLPRIEKNPNPLGIFHMISLAP 523
E+ FI + G R LYI+P TA I + L K + H+++ P
Sbjct: 481 SEHSFIREE-NNTFTLTNFGKRVADLYINPFTADIIRKGLEGY-KASCEIAYLHLLAFTP 538
Query: 524 DLTPLSYSKRETSMLEDEYYSLMDRLYFELDYENER--KFFRAFKTALVLNAWINEVPEG 581
D +S + E L + L L E YE + + A K AL++ WI+EV E
Sbjct: 539 DGPLVSVGRNEEEELIELLEDLECELLVEEPYEEDEYSLYLNALKVALIMKDWIDEVDED 598
Query: 582 EIVERFNVEPGDIYRIVETAEWLIYSLGEIAKVLEASQEVVDYVNTLRLRVKHGIREELI 641
I+ ++N+ GD+ IVET +WL YS ++K L D + L LRV G++EEL+
Sbjct: 599 TILGKYNIGSGDLRNIVETMDWLTYSAYHLSKELRLDDH-SDKLRILNLRVTDGVKEELL 657
Query: 642 PLMELPMVGRKRARALYNAGFKDL-ESIRNAKPSELLRIEGIGAKIVEGIFKYLGK 696
L+++ VGRKRAR LYN G K L + + N L + +G ++V+ + L +
Sbjct: 658 ELVQIGGVGRKRARLLYNNGIKGLGDVVMNPDRVRNLLGQKLGERVVQEAARLLNR 713
>pir||E72775 probable helicase APE0191 - Aeropyrum pernix (strain K1)
>gi|5103582|dbj|BAA79103.1| (AP000058) 702aa long
hypothetical helicase [Aeropyrum pernix]
Length = 702
Score = 426 bits (1084), Expect = e-118
Identities = 266/698 (38%), Positives = 388/698 (55%), Gaps = 26/698 (3%)
Query: 31 ALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLEEGGKAVYIVPLKALAEEKFREFKD 90
AL +GV +GENL+VA PT SGKT IA +AI N L GG+A Y+VPLK++A EK+ F
Sbjct: 2 ALQAGVEKGENLVVAAPTGSGKTFIALVAIVNSLARAGGRAFYLVPLKSVAYEKYTSFSI 61
Query: 91 WERLGLKVAMATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSSWIRDVKMLVIDEIHLI 150
R+GLK+ ++ GD+ E + ++IAT EKFDSLLR S R+V +L++DEIH +
Sbjct: 62 LSRMGLKLKISVGDFR---EGPPEAPVVIATYEKFDSLLRVSPSLARNVSVLIVDEIHSV 118
Query: 151 GSRDRGATLEFIITQML---GRAQIIGLSATIGNPEELAEWLNAKLIRSDWRPVKLRKGV 207
RG LE I+++ML G AQ++GLSAT+ N E+AEW+ K++ S WRPV LR+ V
Sbjct: 119 SDPKRGPILESIVSRMLASAGEAQLVGLSATVPNAGEIAEWIGGKIVESSWRPVPLREYV 178
Query: 208 FYQGFVFWEDGGSER----YNSWE-ELVYDAVKKGKGALVFVNMRRKAEKTALELAKKVK 262
F + ++ GG Y ++ +L +A++ G ALVF RR+A A AK++
Sbjct: 179 FKEYKLYSPTGGLREVPRVYGLYDLDLAAEAIEDGGQALVFTYSRRRAVTLAKRAAKRLG 238
Query: 263 NYLDRKELRELRELAESLEENPTN--EKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGL 320
L +E R A E P + E+LA + +G+A+HHAGL R VE+ FR G
Sbjct: 239 RRLSSREARVYSAEASRAEGAPRSVAEELASLIAAGIAYHHAGLPPSLRKTVEEAFRAGA 298
Query: 321 IKVVVATPTLSAGINTPAFRVIIRDTWRYSEFGMERIPVLEVQQMMGRAGRPRYDEVGEA 380
+KVV +TPTL+AG+N PA RV+I +RY E I V E +QM GRAGRP DE GEA
Sbjct: 299 VKVVYSTPTLAAGVNLPARRVVIDSYYRYEAGFREPIRVAEYKQMAGRAGRPGLDEFGEA 358
Query: 381 IIVSTT-EEPSLVIDHYIKGKPEKLFSQLSNESILRSQILALIATFGYSEFKEIYDFLER 439
IIV+ + P +I YI+ PE++ S+L+ LR IL ++A G I
Sbjct: 359 IIVAERLDRPEDLISGYIRAPPERVESRLAGLRGLRHFILGIVAPEGEVSIGSIEKVSGL 418
Query: 440 TFYAHQGKDPYMLEEKIRRIIYFLLENEFIEVTLEDEIKPLPLGVRTTKLYIDPMTAKIF 499
T Y+ Q P E I R + L +EV I LG +Y+DP + +F
Sbjct: 419 TLYSLQRGLP---RETIARAVEDLSAWGLVEVK-GWRIAATSLGREVAAVYLDPESVPVF 474
Query: 500 KDTLPRIEKNPNPLGIFHMISLAPDLTPLSYSKRETSMLEDEYYSLMDRLYFELDYENER 559
++ + + + N I ++IS PD+ L ++RE L + R+ +D+
Sbjct: 475 REEVKHLSFD-NEFDILYLISTMPDMVRLPATRREEERLLEAILDASPRMLSSVDWLGPE 533
Query: 560 KFFRAFKTALVLNAWINEVPEGEIVERFNVEPGDIYRIVETAEWLIYSLGEIAKVLEASQ 619
+ A KTA+VL WI+E E I + V GD+ +V TAEW+ L IA L +
Sbjct: 534 EM-AAVKTAVVLKLWIDEASEDTIYGEWGVHTGDLLNMVSTAEWIASGLSRIAPYLGLNS 592
Query: 620 EVVDYVNTLRLRVKHGIREELIPLMELPMVGRKRARALYNAGFKDLESIRNAKPSELLRI 679
+V ++ + R+KHG++ EL+ L+E+P VGR RAR L+ AG++ +E + A+ +L+R+
Sbjct: 593 KVSHILSVIARRIKHGVKPELLQLVEIPGVGRVRARILFEAGYRSIEDLATARAEDLMRL 652
Query: 680 EGIGAKIVEGIFKYLGKEVKITER------PRKGTLDY 711
IG I ++LG+ + E RKG L Y
Sbjct: 653 PLIGPSTARQILEFLGRVDEAREAEAREMLARKGLLSY 690
>emb|CAC11964.1| (AL445065) DNA helicase related protein [Thermoplasma acidophilum]
Length = 674
Score = 400 bits (1016), Expect = e-110
Identities = 254/699 (36%), Positives = 390/699 (55%), Gaps = 43/699 (6%)
Query: 1 MKVGELNVSEKIKEILRERGIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAI 60
MK+ EL ++ + LY Q A+ + +G N++V++PTA+GKTLIA AI
Sbjct: 1 MKISELGYDRAFLQLFDGNDFQ-LYDHQRMAIEQ-IRKGRNVVVSVPTAAGKTLIAYSAI 58
Query: 61 ANKLLEEGGKAVYIVPLKALAEEKFREFKDWERLGLKVAMATGDYDSKDEWLGKYDIIIA 120
+ + K++YIVPL++LA EKF E LGLKV M+ GDYD +++ +YD +I
Sbjct: 59 Y-ETFQRNLKSIYIVPLRSLAMEKFSELSRLRDLGLKVKMSIGDYDDSPDFIKRYDAVIL 117
Query: 121 TAEKFDSLLRHGSSWIRDVKMLVIDEIHLIGSRDRGATLEFIIT---QMLGRAQIIGLSA 177
T+EK DSLL H + DV +LV+DEIH IG RG TLE + + + +I+ LSA
Sbjct: 118 TSEKADSLLHHDPYILNDVGLLVLDEIHTIGDESRGPTLETVASIARYVNPDVRILALSA 177
Query: 178 TIGNPEELAEWLNAKLIRSDWRPVKLRKGVFYQGFVFWEDGGSERYNSWEELVYDAVKKG 237
T+ N ELA WL+A LI+SD+RPV L+ G+ Y+ ++ DG S +++ + V+
Sbjct: 178 TVSNAMELASWLDASLIKSDFRPVPLKTGILYRDQLYL-DGKRRSGVSINQIIRETVEDN 236
Query: 238 KGALVFVNMRRKAEKTALELAKKVKNYLDRKELRELRELAESLEENPTNEKLAKALLSGV 297
L+FV+ R+KAE TA +LA+ + + K S E N ++ L + L GV
Sbjct: 237 GQVLMFVSSRKKAEDTARDLAQIFGSDANIK--------ISSDETNVYDDMLNEILPRGV 288
Query: 298 AFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWRYSEFGMERI 357
AFHHAGL D+R +E FR IKV+VATPTL+AG+N PA VI+RD R+ G+ +
Sbjct: 289 AFHHAGLSNDQRAFIEREFRARRIKVIVATPTLAAGVNLPARLVIVRDITRWGSDGISYL 348
Query: 358 PVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKGKPEKLFSQLSNESILRSQ 417
+E++QM+GRAGRP YD+ G +I +++ Y+ PE + S L NE+ +R
Sbjct: 349 TNMEIKQMIGRAGRPGYDQYGIGLIYVSSQSSYEAAKDYLSTDPEPVVSYLGNEAKVRFN 408
Query: 418 ILALIATFGYSEFKEIYDFLERT-FYAHQGKDPYMLEEKIRRIIYFLLENEFIEVTLEDE 476
LA I+ +I F E T F++ GKD +LEEKI + FL +N FI+ + +
Sbjct: 409 TLAAISMGLARSPSDIMKFYETTLFFSQNGKD--LLEEKISASLKFLEKNGFIKQS--PD 464
Query: 477 IKPLPLGVRTTKLYIDPMTAKIFKDTLPRIEKNPNPLGIFH---MISLAPDLTPLSYSKR 533
++ LG T+ LYIDP +A L ++ P + H ISL ++ P +
Sbjct: 465 LRTTQLGKVTSDLYIDPESA------LRLVDFFDGPADVDHAIYYISLCREIVPFNIKDD 518
Query: 534 ETSMLEDEYYSLMDRLYFELDYENERKFFRAFKTALVLNAWINEVPEGEIVERFNVEPGD 593
++M E+ + + ++D A KTA+VL WI+E + +++ + PGD
Sbjct: 519 YSAM---EFLDDIGLIDGDID---------AAKTAIVLRDWISEASYKYLYDKYGIAPGD 566
Query: 594 IYRIVETAEWLIYSLGEIAKVLEASQEVVDYVNTLRLRVKHGIREELIPLMELPMVGRKR 653
+ + A+WL YSL +++ + + EV + L LR+K GIRE+++ L+ +P VGR R
Sbjct: 567 MQARISMADWLSYSLAKLSSIYK--PEVRRMLEILNLRIKEGIREDILQLVLIPGVGRVR 624
Query: 654 ARALYNAGFKDLESIRNAKPSELLRIEGIGAKIVEGIFK 692
AR LY+AG + +E + +A P + I G + I +
Sbjct: 625 ARRLYDAGLRSIEDVASASPDRIKAIYGFSDTLANAIIR 663
>pir||C69208 DNA helicase related protein - Methanobacterium thermoautotrophicum
(strain Delta H) >gi|2621900|gb|AAB85310.1| (AE000858)
DNA helicase related protein [Methanobacterium
thermoautotrophicum]
Length = 690
Score = 316 bits (802), Expect = 4e-85
Identities = 222/695 (31%), Positives = 363/695 (51%), Gaps = 49/695 (7%)
Query: 21 IEELYPPQAEALTSGVLEGE-NLLVAIPTASGKTLIAEIAIANKLLEEGGKAVYIVPLKA 79
I EL P Q A+ +G LE E N ++AIPTASGKTL+ IA A K + EGG+ +Y VPL +
Sbjct: 19 IRELNPAQRSAIEAGYLESEDNYIIAIPTASGKTLLGIIA-ALKTVMEGGRVIYTVPLLS 77
Query: 80 LAEEKFREFKDWERLGLKVAMATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSSWIRDV 139
+ EK +EF+ E G++V KD DI + E FDSL R + +R+V
Sbjct: 78 IQNEKIKEFRKLEEHGIRVG--------KDPRTS--DIAVMVFESFDSLTRFSWNILREV 127
Query: 140 KMLVIDEIHLIGSRDRGATLEFIITQ---MLGRAQIIGLSATIGNPEELAEWLNAKLIRS 196
+L++DE H+IG RG +E IT+ + +I+ LSAT+ N +E+A WL+A+++
Sbjct: 128 DLLIVDEFHMIGEYTRGPVIESAITRARTLNPSVRIVALSATLSNMDEIAGWLDARVVEH 187
Query: 197 DWRPVKLRKGVFYQGFVFWEDGGSERYNSWEELVYDAVKKGKGALVFVNMRRKAEKTALE 256
D+RPV L + V G E+ + +++ +++ G L FV+ RR E A
Sbjct: 188 DYRPVPLHREVLDTEMF----GVREKNDVVLKVLERSLEDGSQTLAFVSTRRFTESLASH 243
Query: 257 LAKKVKNYLDRKELRELRELAESLEENPTNE---------KLAKALLSGVAFHHAGLGRD 307
LA K+ + + RE+A + E P + KLA+ L +G+AFHHAGL
Sbjct: 244 LADKISGKIPDDMVESFREVAGKVLEVPKSRGSPPTSTCLKLAECLEAGIAFHHAGLFNR 303
Query: 308 ERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWRYSEFGMERIPVLEVQQMMG 367
+R ++ED FR G I ++ ATP+L G+N P+ V+IRD R++ G RIPV + +QM G
Sbjct: 304 QREIIEDEFRDGNILMITATPSLMYGVNLPSRTVVIRDYTRWTSQGPRRIPVFDYEQMSG 363
Query: 368 RAGRPRYDEVGEAIIVSTTEEPSLVI-DHYIKGKPEKLFSQ-LSNESILRSQILALIATF 425
RAGRP+YD+ G + +++ + + ++ + ++YI+G+ E+ S+ + N L QI+A +A+
Sbjct: 364 RAGRPQYDDAGYSYLIARSHDEAMDLEEYYIRGEVERTTSRIIENRDALYRQIIAQVASG 423
Query: 426 GYSEFKEIYDFLERTFYAHQGKDPYMLEEKIRRIIYFLLENEFIEVTLEDEIKPLPLGVR 485
+E+ DF TFY +Q + + I + +EN + + P P G
Sbjct: 424 LSGTTEELADFFRNTFYGYQMVEGPFSDSFGMDSIQYEVENATEYLMRNRILYPGPEGFS 483
Query: 486 TTKLYIDPMTAKIFKDTLPRIEKNPNPLG------IFHMISLAPDLTPLSYSKRETSMLE 539
T+ + + +T ++ + + + + + I+ PD+ +S+ R++ +
Sbjct: 484 ATEFGLLIAKSNYSVETAIKLHQFASEMDEMDIYRLIYEITRTPDMPLISFKGRKSR--D 541
Query: 540 DEYYSLMDRLYFELDYENERKFFRAFKTALVLNAWINEVPEGEIVERFNVEPGDIYRIVE 599
LM+ F +D NE TA L WINE E EI F+V R
Sbjct: 542 PVRDKLMEHGLFLMDVGNEE------ATAAALIEWINERTEYEIENAFHVYAASTRRSAY 595
Query: 600 TAEWLIYSLGEIAKVLEASQEVVDYVNTLRLRVKHGIREELIPL-MELPMVGRKRARALY 658
A ++ G+I +++ + + L R+ +G++E+ IPL + + +GR RAR +
Sbjct: 596 EASKIVKFFGKICEIMGVYRH-SSQLEILSARLYYGVKEDAIPLVVGVRGLGRVRARKII 654
Query: 659 NAGFKDLESIRNAKPSELLRIEGIGAKIVEGIFKY 693
+DL R+ + EL RI+GIG K+ I +Y
Sbjct: 655 KTFGEDL---RHVREDELKRIDGIGPKMAGAIRRY 686
>pir||C64440 DNA repair protein RAD24 homolog (intein-containing) -
Methanococcus jannaschii >gi|1499976|gb|AAB99126.1|
(U67555) putative SKI2-family helicase [Methanococcus
jannaschii]
Length = 1195
Score = 297 bits (753), Expect = 2e-79
Identities = 174/345 (50%), Positives = 227/345 (65%), Gaps = 21/345 (6%)
Query: 10 EKIKEILRERGIEELYPPQAEALTSGVLE-GENLLVAIPTASGKTLIAEIAIANKLLE-- 66
+KI EIL++ GI EL PPQ +AL G+L+ +N L++IPTASGKTLI E+A+ N LL+
Sbjct: 2 DKILEILKDFGIVELRPPQKKALERGLLDKNKNFLISIPTASGKTLIGEMALINHLLDGN 61
Query: 67 ---EGGKAVYIVPLKALAEEKFREFKD-WERLGLKVAMATGDYDSKDEWLGKYDIIIATA 122
K ++IVPLKALA EK+ EFK +ER GL++A++ GDYD +DE L KY +II TA
Sbjct: 62 KNPTNKKGIFIVPLKALASEKYEEFKSKYERYGLRIALSIGDYD-EDEDLSKYHLIITTA 120
Query: 123 EKFDSLLRHGSSWIRDVKMLVIDEIHLIGSRDRGATLEFIITQMLG-RAQIIGLSATIGN 181
EK DSL RH WI DV ++V+DEIHLI RG TLE ++T++ QIIGLSATIGN
Sbjct: 121 EKLDSLWRHKIDWINDVSVVVVDEIHLINDETRGGTLEILLTKLKEFNVQIIGLSATIGN 180
Query: 182 PEELAEWLNAKLIRSDWRPVKLRKGVFYQGFVFWEDGGSERY-----NSWEELVYDAVKK 236
P+ELAEWLNA+LI DWRPV+L+KG++ + + +G N LV D VK+
Sbjct: 181 PDELAEWLNAELIVDDWRPVELKKGIYKNEAIEFINGEIREIKAVDNNDIYNLVVDCVKE 240
Query: 237 GKGALVFVNMRRKAEKTALELAKKVKNYLDRKELRELRELAE---SLEENPTN--EKLAK 291
G LVF N +R A A +L +K +L +E L+E+AE S+ E PT + LA+
Sbjct: 241 GGCCLVFCNTKRNAVNEAKKL--NLKKFLTEEEKIRLKEIAEEILSILEPPTEMCKTLAE 298
Query: 292 ALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINT 336
+L+G AFHHAGL R +VED FRK LIKV+ TPTL NT
Sbjct: 299 CILNGSAFHHAGLTYQHRKIVEDAFRKRLIKVICCTPTLCLNANT 343
Score = 236 bits (597), Expect = 5e-61
Identities = 145/370 (39%), Positives = 221/370 (59%), Gaps = 28/370 (7%)
Query: 331 SAGINTPAFRVIIRDTWRYSEFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPS 390
SAG+N P R I++D R++ GM IP++E+QQ +GRAGRP D GE IIV+ +
Sbjct: 839 SAGLNLPCRRAIVKDLTRFTNKGMRYIPIMEIQQCIGRAGRPGLDPYGEGIIVAKNDRDY 898
Query: 391 LVIDHYIKGKPEKLFSQLSNESILRSQILALIATFGYSEFKEIYD---FLERTFYAHQGK 447
L + KPE ++S+LSN+++LR+Q+L LIAT E ++ YD F+ TFYAHQ
Sbjct: 899 LRAYQALTQKPEPIYSKLSNQAVLRTQLLGLIAT---GEIRDEYDLEWFIRNTFYAHQYG 955
Query: 448 DPYMLEEKIRRIIYFLLENEFIEVTLEDEIKPLPLGVRTTKLYIDPMTAKIFKDTLPRIE 507
+ + + I +I FL ENEFI + P LG R ++LYIDP++AK D L +E
Sbjct: 956 NLREVAKNINEVIRFLEENEFI-----IDFMPTELGKRVSELYIDPLSAKFIIDGLEEME 1010
Query: 508 KNPNPLGIFHMISLAPDLTP--LSYSKRETSMLEDEYYSLMDRLYFELDYENERKFFRAF 565
N + ++IS ++ P Y+ E +++++ MD L + E + AF
Sbjct: 1011 -NEEEIYYLYLISKTLEMMPNLRVYNSEELNLIDE-----MDSLGIK---SFEIEDLEAF 1061
Query: 566 KTALVLNAWINEVPEGEIVERFNVEPGDIYRIVETAEWLIYSLGEIAKVLEASQEVVDYV 625
KTA +L WINEVPE EI++R+ +EPG + VE A W++++L EIAK++ S ++ +
Sbjct: 1062 KTAKMLYDWINEVPEDEILKRYKIEPGILRYKVENAVWIMHALKEIAKLIGKSSDIPE-- 1119
Query: 626 NTLRLRVKHGIREELIPLMELPMVGRKRARALYNAGFKDLESIRNAKPSELLRIEGIGAK 685
L +R+++G +E++I L+ + +GR RAR LYNAG + +E I N PS++ I IG K
Sbjct: 1120 -KLEIRLEYGAKEDIIELLSIKYIGRVRARKLYNAGIRSIEDIIN-NPSKVASI--IGEK 1175
Query: 686 IVEGIFKYLG 695
I + I LG
Sbjct: 1176 IAKKILDELG 1185
>gb|AAG20341.1| (AE005107) pre-mRNA splicing helicase; Brr2 [Halobacterium sp.
NRC-1]
Length = 779
Score = 228 bits (574), Expect = 2e-58
Identities = 195/713 (27%), Positives = 344/713 (47%), Gaps = 66/713 (9%)
Query: 6 LNVSEKIKEILRERGIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLL 65
++V+E + E +E Q EA+ + + N++ + PT SGKT +AE+AI + L
Sbjct: 1 MDVAEVVPEFAEAFPFDEFNAMQREAVPALLESDANVVASAPTGSGKTALAELAIC-QTL 59
Query: 66 EEGGKAVYIVPLKALAEEKFREFKDWERLGLKVAMATGDYDSKDEWLGKYDIIIATAEKF 125
+GG A+++ PL+AL EK E++ +E LG V + TG+ D + D+++ T EK
Sbjct: 60 ADGGTALFVAPLRALTNEKEDEWERFEALGYSVYVVTGERDLNPRRAERADVLVMTPEKA 119
Query: 126 DSLLRHGSS----WIRDVKMLVIDEIHLIGSRDRGATLEFIITQM--LGRAQIIGLSATI 179
DS R S ++ DV+ +VIDE+HL+ S RG+ LE +++++ L +++ LSAT+
Sbjct: 120 DSATRKHDSPRYAFVTDVECVVIDEVHLLDSETRGSVLEVVVSRLRRLCDPRVVALSATM 179
Query: 180 GNPEELAEWLNAKL-----IRSDWRPVKLRKGVFYQGFVFWEDGGSERYN---SWEELVY 231
N ++A+WL+A D+RPV L GV + + ++ +++Y + +L
Sbjct: 180 PNIGDVADWLDATPDTTFEFDDDYRPVDLHAGV--RTYDHGDNPFADKYRRLFTALDLAE 237
Query: 232 DAVKKGKGALVFVNMRRKAEKTALELAKKVKNYLDRKELR-------ELRELAESLEENP 284
+++ +LVFV R+ ++ AKK ++ + ++++ + E+L+
Sbjct: 238 PHLREDGQSLVFVASRQDT----VQAAKKTRDEIAQRDIPVGSRGDYDFHTATEALD--- 290
Query: 285 TNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIR 344
NE L K++L GVAFHHAGL ++ VE FR+G I+V+ +T TL+ G+N PA V+IR
Sbjct: 291 -NETLRKSVLDGVAFHHAGLSTTDKSHVEQWFREGKIRVLFSTSTLAWGVNLPARCVVIR 349
Query: 345 DTWRYSEF-GMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKGKPEK 403
DT + G + L+V QM+GRAGRP YD+VG +V T + + + +
Sbjct: 350 DTKLHDPLEGEVDMSPLDVLQMLGRAGRPGYDDVGYGWVVCDTSDADTY--RTLLDEGHE 407
Query: 404 LFSQLSNESILRSQILALIATFGYSEFKEIYDFLERTFY---AHQGKDPY---MLEEKIR 457
+ S+L L + A IA + ++ +LE TFY A D Y L +++R
Sbjct: 408 IESRLDGN--LAEHLNAEIAMGTIRDLGDVMAWLETTFYYQRAQSAPDAYEFSTLRDRVR 465
Query: 458 RIIYFLLENEFIEVTLEDEIKPLPLGVRTTKLYIDPMTAKIFKDTLPRIEKNPNPLGIFH 517
+ L++ F+E + + LGV + Y+ TA+ F+ I+ + I
Sbjct: 466 ATLDDLIDQGFVETDADLGLSATRLGVLASTYYLRLDTAREFRAV---IDDAADDRAILR 522
Query: 518 MISLAPDLTPLSYSKRETSMLEDEYYSLMDRLYFELDYENERKFFRAFKTALVLNAWINE 577
++ A + +S +S D ++ L + + + K +L A +
Sbjct: 523 AVAAAGEFDSVS-----------ARHSEQDAIHTVLGHSGDEMADGSRKVYAILRASMRG 571
Query: 578 VPEGEIVERFNVEPGDIYRIVETAEWLIYSLGEIAKVLEASQEVVDYVNTLRLRVKHGIR 637
E+ D + I + A L+ +LG + + L R+ G+
Sbjct: 572 AVPSEL-------RSDAWVITQNALRLLAALGAFFDRYDDPMG-ANAAARLEARIDTGVP 623
Query: 638 EELIPLMELPMVGRKRARALYNAGFKDLESIRNAKPSELLRIEGIGAKIVEGI 690
E + L + V RA L++ G +R+A S L+ G+ + E +
Sbjct: 624 EAAVGLTAIEGVAAGRAHKLHDEGIDTPGDVRDAGVSGLVD-AGLAPGVAESV 675
>pir||T13858 probable DNA-directed DNA polymerase (EC 2.7.7.7) I - fruit fly
(Drosophila melanogaster) >gi|2340084|gb|AAB67306.1|
(L76559) mus308 [Drosophila melanogaster]
>gi|7299675|gb|AAF54858.1| (AE003697) mus308 gene
product [Drosophila melanogaster]
Length = 2059
Score = 203 bits (512), Expect = 4e-51
Identities = 193/758 (25%), Positives = 349/758 (45%), Gaps = 102/758 (13%)
Query: 7 NVSEKIKEILRERGIEELYPPQAEALTSGVLEGE--NLLVAIPTASGKTLIAEIAIANKL 64
N+ I+ +++G+ +++ Q E L+ L E NL+ + PT++GKTL++EI + +
Sbjct: 215 NLPMSIQAEYKKKGVVDMFDWQVECLSKPRLLFEHCNLVYSAPTSAGKTLVSEILMLKTV 274
Query: 65 LEEGGKAVYIVPLKALAEEKFREFKDW-ERLGLKVAMATGDYDSKDEWLGKYDIIIATAE 123
LE G K + I+P ++ EK +D G +V G Y + + + I T E
Sbjct: 275 LERGKKVLLILPFISVVREKMFYMQDLLTPAGYRVEGFYGGYTPPGGFESLH-VAICTIE 333
Query: 124 KFDSLLRH--GSSWIRDVKMLVIDEIHLIGSRDRGATLEFIITQMLGRA-------QIIG 174
K +S++ + + M+V+DE+HLI + RG LE ++ ++L + Q+I
Sbjct: 334 KANSIVNKLMEQGKLETIGMVVVDEVHLISDKGRGYILELLLAKILYMSRRNGLQIQVIT 393
Query: 175 LSATIGNPEELAEWLNAKLIRSDWRPVKLRKGVFYQGFVFWED----------------G 218
+SAT+ N + L WL+A+L +++RPV L++ + G V ++ G
Sbjct: 394 MSATLENVQLLQSWLDAELYITNYRPVALKE-MIKVGTVIYDHRLKLVRDVAKQKVLLKG 452
Query: 219 GSERYNSWEELVYDAVKKGKGALVFVNMRRKAEKTALELAKKVKNYLDRKEL-------- 270
+ L + + +G +VF + E A++LA + + + +
Sbjct: 453 LENDSDDVALLCIETLLEGCSVIVFCPSKDWCENLAVQLATAIHVQIKSETVLGQRLRTN 512
Query: 271 ---RELRELAESLEENPT--NEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVV 325
R + E+ + L + PT + ++KA+ AFHHAGL +ER ++E +F+ G +KV+V
Sbjct: 513 LNPRAIAEVKQQLRDIPTGLDGVMSKAITYACAFHHAGLTTEERDIIEASFKAGALKVLV 572
Query: 326 ATPTLSAGINTPAFRVIIRDTWRYSEFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVST 385
AT TLS+G+N PA RV+IR FG +++ L +QM+GRAGR D +GE+I++
Sbjct: 573 ATSTLSSGVNLPARRVLIRSPL----FGGKQMSSLTYRQMIGRAGRMGKDTLGESILICN 628
Query: 386 TEEPSLVIDHYIKG-KPEKLFSQLSNESILRSQILALIATFGYSEFKEIYDFL------- 437
+ D + +P + + L+ +L +I++ G + KE DF
Sbjct: 629 EINARMGRDLVVSELQPITSCLDMDGSTHLKRALLEVISS-GVANTKEDIDFFVNCTLLS 687
Query: 438 -ERTFYA-HQGKDPYMLEEKIRRIIYFLLENEFIEVTLEDEIKPLPLGVRTTKLYI-DPM 494
++ F+A + D I + FL+E EF+ + +E R T +Y+ +
Sbjct: 688 AQKAFHAKEKPPDEESDANYINDALDFLVEYEFVRLQRNEE--------RETAVYVATRL 739
Query: 495 TAKIFKDTLP---------RIEKNPNPLGIFHMISLAPDLTPLS---------------- 529
A ++P ++K+ + + +TP S
Sbjct: 740 GAACLASSMPPTDGLILFAELQKSRRSFVLESELHAVYLVTPYSVCYQLQDIDWLLYVHM 799
Query: 530 YSKRETSM--------LEDEYYSLMDRLYFELDYENERKFFRAFKTALVLNAWINEVPEG 581
+ K + M + D + R +LDY+ + + + F AL L +NE P
Sbjct: 800 WEKLSSPMKKVGELVGVRDAFLYKALRGQTKLDYK-QMQIHKRFYIALALEELVNETPIN 858
Query: 582 EIVERFNVEPGDIYRIVETAEWLIYSLGEIAKVLEASQEVVDYVNTLRLRVKHGIREELI 641
+V ++ G + + + A + L+ S + V+ + R+ GI +LI
Sbjct: 859 VVVHKYKCHRGMLQSLQQMASTFAGIVTAFCNSLQWSTLAL-IVSQFKDRLFFGIHRDLI 917
Query: 642 PLMELPMVGRKRARALYNAGFKDLESIRNAKPSELLRI 679
LM +P + +KRARAL++AG L + A P EL ++
Sbjct: 918 DLMRIPDLSQKRARALFDAGITSLVELAGADPVELEKV 955
>emb|CAA11679.1| (AJ223948) RNA helicase [Homo sapiens]
Length = 1257
Score = 202 bits (508), Expect = 1e-50
Identities = 173/538 (32%), Positives = 264/538 (48%), Gaps = 55/538 (10%)
Query: 41 NLLVAIPTASGKTLIAEIAIANKLLE-EGGKAVYIVPLKALAEEKFREFKDW--ERLGLK 97
N+L+ PT SGKT+ AE+AI + KAVYI PLKAL E+ ++K E+LG K
Sbjct: 408 NVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRERMDDWKVRIEEKLGKK 467
Query: 98 VAMATGDYDSKDEWLGKYDIIIATAEKFDSLLR--HGSSWIRDVKMLVIDEIHLIGSRDR 155
V TGD + + K D+I+ T EK+D + R ++++ V +L+IDEIHL+G +R
Sbjct: 468 VIELTGDVTPDMKSIAKADLIVTTPEKWDGVSRSWQNRNYVQQVTILIIDEIHLLGE-ER 526
Query: 156 GATLEFII--TQMLGR-----AQIIGLSATIGNPEELAEWLNAKLI-----RSDWRPVKL 203
G LE I+ T + +I+GLS + N +LA+WLN K + R RPV L
Sbjct: 527 GPVLEVIVSRTNFISSHTEKPVRIVGLSTALANARDLADWLNIKQMGLFNFRPSVRPVPL 586
Query: 204 RKGVFYQGFVFWEDGGSERYNSWEELVYDAVKK---GKGALVFVNMRRKAEKTALELAKK 260
V QGF R S + + A++ K L+FV+ RR+ TALEL
Sbjct: 587 E--VHIQGFP--GQHYCPRMASMNKPAFQAIRSHSPAKPVLIFVSSRRQTRLTALELIAF 642
Query: 261 VKNYLDRKELRELRELA-ESLEENPTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKG 319
+ D K+ + E E++ + L L G+ HHAGL +R VE+ F
Sbjct: 643 LATEEDPKQWLNMDEREMENIIATVRDSNLKLTLAFGIGMHHAGLHERDRKTVEELFVNC 702
Query: 320 LIKVVVATPTLSAGINTPAFRVIIRDTWRYSEFGMER----IPVLEVQQMMGRAGRPRYD 375
++V++AT TL+ G+N PA VII+ T Y G R P+ +V QMMGRAGRP++D
Sbjct: 703 KVQVLIATSTLAWGVNFPAHLVIIKGTEYYD--GKTRRYVDFPITDVLQMMGRAGRPQFD 760
Query: 376 EVGEAIIVSTTEEPSLVIDHYIKGKPEKLFSQLSNESILRSQILALIATFGYSEFKEIYD 435
+ G+A+I+ + D Y K E + S +L + A IA + ++ D
Sbjct: 761 DQGKAVIL----VHDIKKDFYKKFLYEPFPVESSLLGVLSDHLNAEIAGGTITSKQDALD 816
Query: 436 FLERTFYAHQ---GKDPYML----EEKIRRIIYFLLENEFIEVTL-------ED--EIKP 479
++ T++ + Y L + + + + L+E IE+ L ED I+P
Sbjct: 817 YITWTYFFRRLIMNPSYYNLGDVSHDSVNKFLSHLIEKSLIELELSYCIEIGEDNRSIEP 876
Query: 480 LPLGVRTTKLYIDPMTAKIFKDTLPRIEKNPNPLGIFHMISLAPDLTPLSYSKRETSM 537
L G + Y+ T K+FKD R++ + + ++S A + T L E M
Sbjct: 877 LTYGRIASYYYLKHQTVKMFKD---RLKPECSTEELLSILSDAEEYTDLPVRHNEDHM 931
>emb|CAB87588.1| (AL121965) dJ161I14.1 (RNA helicase) [Homo sapiens]
Length = 1133
Score = 201 bits (506), Expect = 2e-50
Identities = 167/504 (33%), Positives = 251/504 (49%), Gaps = 52/504 (10%)
Query: 41 NLLVAIPTASGKTLIAEIAIANKLLE-EGGKAVYIVPLKALAEEKFREFKDW--ERLGLK 97
N+L+ PT SGKT+ AE+AI + KAVYI PLKAL E+ ++K E+LG K
Sbjct: 627 NVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRERMDDWKVRIEEKLGKK 686
Query: 98 VAMATGDYDSKDEWLGKYDIIIATAEKFDSLLR--HGSSWIRDVKMLVIDEIHLIGSRDR 155
V TGD + + K D+I+ T EK+D + R ++++ V +L+IDEIHL+G +R
Sbjct: 687 VIELTGDVTPDMKSIAKADLIVTTPEKWDGVSRSWQNRNYVQQVTILIIDEIHLLGE-ER 745
Query: 156 GATLEFII--TQMLGR-----AQIIGLSATIGNPEELAEWLNAKLI-----RSDWRPVKL 203
G LE I+ T + +I+GLS + N +LA+WLN K + R RPV L
Sbjct: 746 GPVLEVIVSRTNFISSHTEKPVRIVGLSTALANARDLADWLNIKQMGLFNFRPSVRPVPL 805
Query: 204 RKGVFYQGFVFWEDGGSERYNSWEELVYDAVKK---GKGALVFVNMRRKAEKTALELAKK 260
V QGF R S + + A++ K L+FV+ RR+ TALEL
Sbjct: 806 E--VHIQGFP--GQHYCPRMASMNKPAFQAIRSHSPAKPVLIFVSSRRQTRLTALELIAF 861
Query: 261 VKNYLDRKELRELRELA-ESLEENPTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKG 319
+ D K+ + E E++ + L L G+ HHAGL +R VE+ F
Sbjct: 862 LATEEDPKQWLNMDEREMENIIATVRDSNLKLTLAFGIGMHHAGLHERDRKTVEELFVNC 921
Query: 320 LIKVVVATPTLSAGINTPAFRVIIRDTWRYSEFGMER----IPVLEVQQMMGRAGRPRYD 375
++V++AT TL+ G+N PA VII+ T Y G R P+ +V QMMGRAGRP++D
Sbjct: 922 KVQVLIATSTLAWGVNFPAHLVIIKGTEYYD--GKTRRYVDFPITDVLQMMGRAGRPQFD 979
Query: 376 EVGEAIIVSTTEEPSLVIDHYIKGKPEKLFSQLSNESILRSQILALIATFGYSEFKEIYD 435
+ G+A+I+ + D Y K E + S +L + A IA + ++ D
Sbjct: 980 DQGKAVIL----VHDIKKDFYKKFLYEPFPVESSLLGVLSDHLNAEIAGGTITSKQDALD 1035
Query: 436 FLERTFYAHQ---GKDPYML----EEKIRRIIYFLLENEFIEVTL-------ED--EIKP 479
++ T++ + Y L + + + + L+E IE+ L ED I+P
Sbjct: 1036 YITWTYFFRRLIMNPSYYNLGDVSHDSVNKFLSHLIEKSLIELELSYCIEIGEDNRSIEP 1095
Query: 480 LPLGVRTTKLYIDPMTAKIFKDTL 503
L G + Y+ T K+FKD L
Sbjct: 1096 LTYGRIASYYYLKHQTVKMFKDRL 1119
Score = 96.0 bits (235), Expect = 1e-18
Identities = 63/190 (33%), Positives = 104/190 (54%), Gaps = 20/190 (10%)
Query: 241 LVFVNMRRKAEKTALELAKKVKN-----YLDRKELRELRELAESLEENPTNEKLAKALLS 295
+VFV+ R +TA+ L ++ KN + + + LAE + N+++ +
Sbjct: 2 MVFVHARNATVRTAMSLIERAKNCGHIPFFFPTQGHDY-VLAEKQVQRSRNKQVRELFPD 60
Query: 296 GVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWRYS--EFG 353
G + HHAG+ R +R LVE+ F G IKV+V T TL+ G+N PA VII+ T Y+
Sbjct: 61 GFSIHHAGMLRQDRNLVENLFSNGHIKVLVCTATLAWGVNLPAHAVIIKGTQIYAAKRGS 120
Query: 354 MERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKGKPEKLFSQLSNESI 413
+ +L+V Q+ GRAGRP++D+ GE II++T ++ + HY+ + L+ +
Sbjct: 121 FVDLGILDVMQIFGRAGRPQFDKFGEGIIITTHDK----LSHYL--------TLLTQRNP 168
Query: 414 LRSQILALIA 423
+ SQ L +A
Sbjct: 169 IESQFLESLA 178
>gb|AAF50481.1| (AE003556) CG7972 gene product [Drosophila melanogaster]
Length = 1051
Score = 200 bits (504), Expect = 4e-50
Identities = 205/777 (26%), Positives = 351/777 (44%), Gaps = 127/777 (16%)
Query: 10 EKIKE-ILRERGIEELYPPQAEALT-SGVLEGENLLVAIPTASGKTLIAEIAIANKLLEE 67
+K+K+ IL +GI LY Q E L + + +NL+ A+PT+ GKTL+AEI + +LL
Sbjct: 249 DKVKKMILEHKGINSLYEWQDECLNLPAIRQRKNLIYALPTSGGKTLVAEILMLRELLCR 308
Query: 68 GGKAVYIVPLKALAEEKFREFK----DWERLGLKVAMATGDYDSKDEWLGKYDIIIATAE 123
++I+P ++ +EK D + + + G + + + IA+ E
Sbjct: 309 ERNVLFILPYVSIVQEKVSAMSPFAIDLDFIVEEYTAGKGKCPPQPR-RKRRSLFIASIE 367
Query: 124 K----FDSLLRHGSSWIRDVKMLVIDEIHLIGSRDRGATLEFIITQML---GRAQIIGLS 176
K DSL+ ++ ++V+DE+HLIG + RGATLE +T+++ QI+G+S
Sbjct: 368 KGAVLMDSLI--DVQRPHEIGLVVVDELHLIGEKGRGATLEAFLTKVMFLNANIQIVGMS 425
Query: 177 ATIGNPEELAEWLNAKLIRSDWRPVKLRKGVFYQGFVFWEDGGSERY-------NSWEEL 229
ATIGN E++ +LNA + +RPV+L++ + + + + S E
Sbjct: 426 ATIGNLSEISSFLNADVYTRGFRPVELKEYIKCGPDLLEINSAGQTLEEIFVPSRSVEYN 485
Query: 230 VYDAVKKGKG---------------ALVFVNMRRKAEKTALELAKKV-KNYLDRKELREL 273
+AVK+ LVF R+ E AL L++ V K+ E
Sbjct: 486 YSEAVKRADPDHLAGLISECAPEHCCLVFCPSRKNCENVALLLSRIVPKHKFFEHRRSEK 545
Query: 274 RELAESLEE--NPTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLS 331
+L ++L++ + LAK L G+A+HH+GL DER +E +R G++ V+ T TL+
Sbjct: 546 LDLMDALDKMCGILSPVLAKTLPYGIAYHHSGLTTDERKYIETAYRFGVVTVICCTSTLA 605
Query: 332 AGINTPAFRVIIRDTWRYSEFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSL 391
AG+N PA RVIIR + G E + + + +QM+GRAGR E GE+I+++ +++ L
Sbjct: 606 AGVNLPAKRVIIRAPY----VGQEFLTLCKYKQMVGRAGRAGLGEAGESILIAQSKDNLL 661
Query: 392 VIDHYIKGKPEKLFSQLSNESI-LRSQILALIATFGYSEFKEIYDFLERTFYAHQGKD-P 449
V + L S NE++ L+S IL+++ +++ + T + Q K
Sbjct: 662 VGQMLFSPMDKALSSLDQNEAVGLQSLILSVVGLNLAECRRDLNRLVNSTLLSVQAKSLE 721
Query: 450 YMLEEKIRRIIYFLLENEFIE---------------VTLED------------------- 475
+ E + RI+ + +N+ ++ +T +D
Sbjct: 722 VAVNEIVLRILREMFKNKVLQLAEPQAKSKINSSDIITSQDVSQANRPAGDRRLLIGQST 781
Query: 476 EIKPLPLGVRTTKLYIDPMTAKIFKDTLPRIEKNPNPLGIFHMISLAPDLTPLSYSKRET 535
K +G K ID A L + ++ H++ L + ++ E
Sbjct: 782 PFKLTNIGRAAFKAGIDYKRANAIHKELKQAQQQLILTNYLHLLYLV-----VCFNSNER 836
Query: 536 SMLEDEYY----SLMDRLYFELDYENERKF----------FRAFKT-------------- 567
DE + S++ +Y L +++ F R FKT
Sbjct: 837 G---DELFPADASILFGVYTSLPLDSQAMFKQLGFTEAHAARLFKTQSVQGPLSLQLNRL 893
Query: 568 --ALVLNAWINEVPEGEIVERFNVEPGDIYRIVETAEWLIYSLGEIAKVLEASQEVVDYV 625
L+L +N +P + ++NVE G + ++ + + I ++ E +E Y
Sbjct: 894 YKVLILADILNLLPIPSVASKYNVERGTLQHLISQS---TAAASAIVRLCEELEEFWCY- 949
Query: 626 NTLRLRVKHGIRE----ELIPLMELPMVGRKRARALYNAGFKDLESIRNAKPSELLR 678
L R+ H + EL PLMELP V RAR LY AGF+ + I +PS L++
Sbjct: 950 KPLFERILHKMDRCGTFELEPLMELPAVKINRARQLYAAGFQTIGDIARVRPSHLVQ 1006
>pir||B75191 probable ATP-dependent RNA helicase PAB2313 - Pyrococcus abyssi
(strain Orsay) >gi|5457486|emb|CAB48977.1| (AJ248283)
ATP-dependent RNA helicase, putative [Pyrococcus abyssi]
Length = 855
Score = 198 bits (497), Expect = 3e-49
Identities = 177/548 (32%), Positives = 262/548 (47%), Gaps = 92/548 (16%)
Query: 1 MKVGELNVSEKIKEILRERGIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAI 60
M + EL++ EK K+IL+ GI+EL P Q A+ SG+LEGENLLV TASGKTLI E+A
Sbjct: 194 MTIDELDIPEKFKDILKLEGIKELLPVQVLAIKSGLLEGENLLVVSATASGKTLIGELAG 253
Query: 61 ANKLLEEGGKAVYIVPLKALAEEKFREF-KDWERLGLKVAMATG--DYDSKDEWLG---- 113
K L G K +++VPL ALA +K+ +F + + +LGLKVA+ G +++E +
Sbjct: 254 IPKAL-NGKKMLFLVPLVALANQKYEDFRRRYSKLGLKVAIRVGMSRIKTREEPVVVDTG 312
Query: 114 -KYDIIIATAEKFDSLLRHGSSWIRDVKMLVIDEIHLIGSRDRGATLEFIIT---QMLGR 169
DII+ T E D LLR G I +V +VIDEIH++ +RG L+ +I ++
Sbjct: 313 IDADIIVGTYEGIDYLLRAGKK-IGNVGTIVIDEIHMLDDEERGPRLDGLIARLRKLYPG 371
Query: 170 AQIIGLSATIGNPEELAEWLNAKLIRSDWRPVKLRKGVFYQGFVFWEDGGSERYNSWEEL 229
AQ IGLSATIGNPEELA+ L KL+ D RPV L + + SE++ +L
Sbjct: 372 AQFIGLSATIGNPEELAKALGMKLVLYDERPVDLERHLVI------ARNESEKWRLIAKL 425
Query: 230 --VYDAVKKGKG----ALVFVNMRRKAEKTALELAKKVKNYLDRKELRELRELAESLEEN 283
V + KG +VF RR+ + A L K L+
Sbjct: 426 CKVEAMRRSSKGFKGQTIVFTYSRRRCHELASFLTGK------------------GLKAK 467
Query: 284 PTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVII 343
P +H+GL +R + E F+ +I VVV T L AG++ PA +VI
Sbjct: 468 P---------------YHSGLPYKQRKITEMEFQAQMIDVVVTTAALGAGVDFPASQVIF 512
Query: 344 RDTWRYSEFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKGKPEK 403
G + + V E QM+GRAGRP Y E G+ ++ EP ++G ++
Sbjct: 513 ESL----AMGNKWLSVREFHQMLGRAGRPLYHEKGKVYLM---VEPGRKYSAQMEGTEDE 565
Query: 404 LFSQLS-----------NESILRSQILALIATFGYSEFKEIYDFLERTFYAHQGKDPYML 452
+ +L ++ I +LA F + I + T A++ + +
Sbjct: 566 VALKLLTSPIEPVIVEWSDEIEEDNVLAHACVF--NRLSVIEEVNSLTLGANRSAEKVL- 622
Query: 453 EEKIRRIIYFLLENEFIEVTLEDEIKPLPLGVRTTKLYIDPMTAKIFKDTLPRIEKNPNP 512
EK+ + L + VT P G T+ ++ P A+ ++ L N NP
Sbjct: 623 -EKLEELGMVKLHGGIVRVT--------PYGRATSMSFLLPREAEFIRENL----DNMNP 669
Query: 513 LGIFHMIS 520
L I M+S
Sbjct: 670 LDIAIMLS 677
>pir||A71223 hypothetical protein PH0044 - Pyrococcus horikoshii
>gi|3256429|dbj|BAA29112.1| (AP000001) 855aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 855
Score = 191 bits (480), Expect = 2e-47
Identities = 146/400 (36%), Positives = 207/400 (51%), Gaps = 62/400 (15%)
Query: 1 MKVGELNVSEKIKEILRERGIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAI 60
MKV E+++ E K +L+ GI EL P Q A+ +G+L+GENLLV TASGKTLI E+A
Sbjct: 194 MKVDEVDIPESFKNVLKLEGITELLPVQVLAIKNGLLKGENLLVVSATASGKTLIGELAG 253
Query: 61 ANKLLEEGGKAVYIVPLKALAEEKFREFK-DWERLGLKVAMATG--DYDSKDEWLG---- 113
K L EG K +++VPL ALA +K+ +FK + +LGLKVA+ G +++E +
Sbjct: 254 IPKAL-EGKKMLFLVPLVALANQKYEDFKRRYSKLGLKVAIRVGMSRIKTREEPVVVDTG 312
Query: 114 -KYDIIIATAEKFDSLLRHGSSWIRDVKMLVIDEIHLIGSRDRGATLEFIIT---QMLGR 169
DII+ T E D LLR G I +V +VIDEIH+I +RG L+ +I ++ +
Sbjct: 313 IDADIIVGTYEGVDYLLRSGKK-IGNVGTVVIDEIHMIDDEERGPRLDGLIARLRKLYPK 371
Query: 170 AQIIGLSATIGNPEELAEWLNAKLIRSDWRPVKLRKGVFYQGFVFWEDGGSERYNSWEEL 229
AQ IGLSAT+GNP+ELA L KL+ D RPV L + + SE++ +L
Sbjct: 372 AQFIGLSATVGNPQELARSLGMKLVLYDERPVDLERHLII------ARNESEKWRIIAKL 425
Query: 230 VYDAV--KKGKG----ALVFVNMRRKAEKTALELAKKVKNYLDRKELRELRELAESLEEN 283
V K KG +VF R++ + A L K L+
Sbjct: 426 CKAEVMRKSSKGFKGQTIVFTYSRKRCHELASFLTGK------------------GLKAK 467
Query: 284 PTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVII 343
P +H+GL +R + E F+ +I VVV T L AG++ PA +VI
Sbjct: 468 P---------------YHSGLPYKQRKITEMEFQAQMIDVVVTTAALGAGVDFPASQVIF 512
Query: 344 RDTWRYSEFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIV 383
G + + V E QM+GRAGRP Y E G+ ++
Sbjct: 513 ESL----AMGNKWLSVREFHQMLGRAGRPLYHEKGKVYLI 548
>pir||H64474 hypothetical protein MJ1401 - Methanococcus jannaschii
>gi|1592049|gb|AAB99409.1| (U67580) putative ATP
dependent RNA helicase [Methanococcus jannaschii]
Length = 808
Score = 188 bits (473), Expect = 2e-46
Identities = 141/400 (35%), Positives = 216/400 (53%), Gaps = 67/400 (16%)
Query: 2 KVGELNVSEKIKEILRERGIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIA 61
K+ EL++ E++KEI++ RGIEEL P Q ++ +G+L G++LL+ T+SGKTLI E+A
Sbjct: 190 KIDELDIPEELKEIIKSRGIEELLPVQTLSVKAGLLNGDDLLIISATSSGKTLIGELAGI 249
Query: 62 NKLLEEGGKAVYIVPLKALAEEKFREFKD-WERLGLKVAMATG--------DYDSKDEWL 112
L++ G K +++VPL ALA +K+ EFK+ +E+LG KV++ G D ++ +
Sbjct: 250 KNLIKTGKKFLFLVPLVALANQKYLEFKERYEKLGFKVSLRVGLGRIGKKVDVETSLD-- 307
Query: 113 GKYDIIIATAEKFDSLLRHGSSWIRDVKMLVIDEIHLIGSRDRGATLEFIITQ---MLGR 169
DII+ T E D L+R + ++D+ +VIDEIH + +RGA L+ +I + +
Sbjct: 308 --ADIIVGTYEGIDYLIR--TKRLKDIGTVVIDEIHSLNLEERGARLDGLIGRLRFLFKE 363
Query: 170 AQIIGLSATIGNPEELAEWLNAKLIRSDWRPVKLRKGVFYQGFVFWEDGGSERYNSWEEL 229
AQ I LSATIGNP+ELA+ LNAKL+ + RPV L + + + F + N +E+
Sbjct: 364 AQKIYLSATIGNPKELAKQLNAKLVLYNGRPVPLERHIIFCKNDF------AKLNIIKEI 417
Query: 230 V---YDAVKK---GKGALVFVNMRRKAEKTALELAKKVKNYLDRKELRELRELAESLEEN 283
V + + K L+F R++AE LAK +K+
Sbjct: 418 VKREWQNISKFGYRGQCLIFTYSRKRAE----YLAKALKS-------------------- 453
Query: 284 PTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVII 343
K KA F+H G+ +R VED+F I+ VV T LSAG++ PA VI+
Sbjct: 454 ----KGIKA-----EFYHGGMEYIKRRKVEDDFANQKIQCVVTTAALSAGVDFPASTVIL 504
Query: 344 RDTWRYSEFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIV 383
G + + E QQM GRAGR E+G+ ++
Sbjct: 505 ESL----AMGADWLNPAEFQQMCGRAGRKGMHEIGKVYLL 540
>gi|6321710 Ygr271wp [Saccharomyces cerevisiae] >gi|1723776|sp|P53327|YG5O_YEAST
PUTATIVE HELICASE YGR271W >gi|2131712|pir||S64604
hypothetical protein YGR271w - yeast (Saccharomyces
cerevisiae) >gi|1323493|emb|CAA97301.1| (Z73056) ORF
YGR271w [Saccharomyces cerevisiae]
Length = 1967
Score = 185 bits (464), Expect = 2e-45
Identities = 192/698 (27%), Positives = 317/698 (44%), Gaps = 85/698 (12%)
Query: 40 ENLLVAIPTASGKTLIAEIAIANKLLE-EGGKAVYIVPLKALAEEKFREFKDWER----- 93
EN V PT SGKT++AE+AI + G K VYI P+KAL E+ DW +
Sbjct: 1156 ENAFVGSPTGSGKTIVAELAIWHAFKTFPGKKIVYIAPMKALVRERV---DDWRKKITPV 1212
Query: 94 LGLKVAMATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSS--WIRDVKMLVIDEIHLIG 151
G KV TGD + + I+I T EKFD + R+ + +++DV ++++DEIHL+
Sbjct: 1213 TGDKVVELTGDSLPDPKDVHDATIVITTPEKFDGISRNWQTRKFVQDVSLIIMDEIHLLA 1272
Query: 152 SRDRGATLEFIITQM-------LGRAQIIGLSATIGNPEELAEWLNAK-----LIRSDWR 199
S DRG LE I+++M +++G+S + N ++A WL K S R
Sbjct: 1273 S-DRGPILEMIVSRMNYISSQTKQPVRLLGMSTAVSNAYDMAGWLGVKDHGLYNFPSSVR 1331
Query: 200 PVKLRKGV--FYQGFVFWEDGGSERYNSWEELVYDAVKK---GKGALVFVNMRRKAEKTA 254
PV L+ + F F + + V+ A+K+ K AL+FV RR+ TA
Sbjct: 1332 PVPLKMYIDGFPDNLAF-----CPLMKTMNKPVFMAIKQHSPDKPALIFVASRRQTRLTA 1386
Query: 255 LELAK------KVKNYLDRKELRELRELAESLEENPTNEKLAKALLSGVAFHHAGLGRDE 308
L+L + +L+ + EL+ + T++ L +L G+ HHAGL + +
Sbjct: 1387 LDLIHLCGMEDNPRRFLNIDDEEELQYYLSQV----TDDTLKLSLQFGIGLHHAGLVQKD 1442
Query: 309 RVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWRYSE--FGMERIPVLEVQQMM 366
R + F+K I++++AT TL+ G+N PA VII+ T + G + + ++ QMM
Sbjct: 1443 RSISHQLFQKNKIQILIATSTLAWGVNLPAHLVIIKGTQFFDAKIEGYRDMDLTDILQMM 1502
Query: 367 GRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIK-GKPEKLFSQLSNESILRSQILALIATF 425
GRAGRP YD G A IV T E + H++ G P + S +L + A I +
Sbjct: 1503 GRAGRPAYDTTGTA-IVYTKESKKMFYKHFLNVGFP----VESSLHKVLDDHLGAEITSG 1557
Query: 426 GYSEFKEIYDFLERTFY---AHQGKDPYMLEEKIRRIIYFLLENEFIEVTLE-------- 474
+ +E DFL TF AH Y +E+ + I+ TLE
Sbjct: 1558 SITNKQEALDFLSWTFLFRRAHHNPTYYGIEDDTSTAGVSEHLSSLIDSTLENLRESQCV 1617
Query: 475 ----DEIKPLPLGVRTTKLYIDPMTAKIFKDTLPRIEKNPNPLGIFHMISLAPDLTPLSY 530
D+I P ++ YI +T + L +I + + +SLA + L
Sbjct: 1618 LLHGDDIVATPFLSISSYYYISHLT---IRQLLKQIHDHATFQEVLRWLSLAVEYNELPV 1674
Query: 531 SKRETSMLEDEYYSLMDRLYFELDYENERK---FFRAFKTALVLNAWINEV--PEGEIVE 585
R ++ +E S R E + +E + + KT L+L A ++ V P + ++
Sbjct: 1675 --RGGEIIMNEEMSQQSRYSVESTFTDEFELPMWDPHVKTFLLLQAHLSRVDLPIADYIQ 1732
Query: 586 RFNVEPGDIYRIVETAEWLIYSLGEIAKVLEASQEVVDYVNTLRLRVKHGIREELIPLME 645
D +++ + ++ + ++A L V+ + ++ +K G E P+
Sbjct: 1733 -------DTVSVLDQSLRILQAYIDVASELGYFHTVLTMIKMMQC-IKQGYWYEDDPVSV 1784
Query: 646 LPMVGRKRARALYNAGFKDLESIRNAKPSELLRIEGIG 683
LP + +R + + +E K +LL +E IG
Sbjct: 1785 LPGLQLRRIKDYTFSEQGFIEMTPQQKKKKLLTLEEIG 1822
Score = 143 bits (357), Expect = 7e-33
Identities = 138/561 (24%), Positives = 252/561 (44%), Gaps = 73/561 (13%)
Query: 40 ENLLVAIPTASGKTLIAEIAIANKLLE--------------EGGKAVYIVPLKALAEEKF 85
EN+L+ PT +GKT IA + I N + + + K +Y+ PLKALA E
Sbjct: 304 ENMLICAPTGAGKTDIALLTIINTIKQFSVVNGENEIDIQYDDFKVIYVAPLKALAAEIV 363
Query: 86 REF-KDWERLGLKVAMATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSS---WIRDVKM 141
+F K ++V TGD + +I+ T EK+D + R + + VK+
Sbjct: 364 DKFSKKLAPFNIQVRELTGDMQLTKAEILATQVIVTTPEKWDVVTRKANGDNDLVSKVKL 423
Query: 142 LVIDEIHLIGSRDRGATLEFIITQMLGRAQ-------IIGLSATIGNPEELAEWLNAK-- 192
L+IDE+HL+ DRG +E ++ + L + + IIGLSAT+ N ++A++L
Sbjct: 424 LIIDEVHLL-HEDRGPVIETLVARTLRQVESSQSMIRIIGLSATLPNFMDVADFLGVNRQ 482
Query: 193 ----LIRSDWRPVKLRKGVF-YQGFVFWEDGGSERYNSWEELVYDA----VKKGKGALVF 243
+RP L + + +G + G + + +++ YD +++G +VF
Sbjct: 483 IGMFYFDQSFRPKPLEQQLLGCRG----KAGSRQSKENIDKVAYDKLSEMIQRGYQVMVF 538
Query: 244 VNMRRKAEKTALELAKKVKNY----LDRKELRELRELAESLEENPTNEKLAKALLSGVAF 299
V+ R++ K+A K ++ L + E + + SL +N ++ + + G
Sbjct: 539 VHSRKETVKSARNFIKLAESNHEVDLFAPDPIEKDKYSRSLVKN-RDKDMKEIFQFGFGI 597
Query: 300 HHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWRY--SEFGMERI 357
HHAG+ R +R L E F+ G IKV+ T TL+ G+N PA VII+ T Y + G +
Sbjct: 598 HHAGMARSDRNLTEKMFKDGAIKVLCCTATLAWGVNLPADCVIIKGTQVYDSKKGGFIDL 657
Query: 358 PVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKGKPEKLFSQLSNESILRSQ 417
+ +V Q+ GR GRP + I+ T+ + +DHY+ ++ + S L
Sbjct: 658 GISDVIQIFGRGGRPGFGSANGTGILCTSNDR---LDHYVSLITQQHPIESRFGSKLVDN 714
Query: 418 ILALIATFGYSEFKEIYDFLERTF---------------YAHQGKDPYMLEEKIRRIIYF 462
+ A I+ + E ++L T+ + DP + E + + I+
Sbjct: 715 LNAEISLGSVTNVDEAIEWLGYTYMFVRMRKNPFTYGIDWEEIANDPQLYERRRKMIVVA 774
Query: 463 LLENEFIEVTLEDEIK----PLPLGVRTTKLYIDPMTAKIFKDTLPRIEKNPNPLGIFHM 518
+++ + DE+ LG ++ Y+ + +IF + + M
Sbjct: 775 ARRLHALQMIVFDEVSMHFIAKDLGRVSSDFYLLNESVEIFNQ---MCDPRATEADVLSM 831
Query: 519 ISLAPDLTPLSYSKRETSMLE 539
IS++ + + + + E+ L+
Sbjct: 832 ISMSSEFDGIKFREEESKELK 852
>dbj|BAB10376.1| (AB006696) RNA helicase [Arabidopsis thaliana]
Length = 2157
Score = 185 bits (464), Expect = 2e-45
Identities = 166/554 (29%), Positives = 263/554 (46%), Gaps = 59/554 (10%)
Query: 41 NLLVAIPTASGKTLIAEIAIANKLLEEGG-KAVYIVPLKALAEEKFREFKDWER-----L 94
N+LV PT SGKT+ AE+A+ + K VYI PLKA+ E+ DW++ L
Sbjct: 1373 NVLVGAPTGSGKTISAELAMLRLFSTQPDMKVVYIAPLKAIVRERMN---DWKKHLVAPL 1429
Query: 95 GLKVAMATGDYDSKDEWLGKYDIIIATAEKFDSLLR--HGSSWIRDVKMLVIDEIHLIGS 152
G ++ TGDY L DIII+T EK+D + R H S+++ V ++++DEIHL+G+
Sbjct: 1430 GKEMVEMTGDYTPDLVALLSADIIISTPEKWDGISRNWHTRSYVKKVGLVILDEIHLLGA 1489
Query: 153 RDRGATLEFIITQML-------GRAQIIGLSATIGNPEELAEWLNAKLI-----RSDWRP 200
DRG LE I+++M + +GLS + N +LA+WL I + RP
Sbjct: 1490 -DRGPILEVIVSRMRYISSQTERSVRFVGLSTALANAGDLADWLGVGEIGLFNFKPSVRP 1548
Query: 201 VKLRKGVF-YQGFVFWEDGGSERYNSWEELVYDAV---KKGKGALVFVNMRRKAEKTALE 256
V + + Y G + R NS + Y A+ K L+FV+ RR+ TAL+
Sbjct: 1549 VPIEVHIQGYPGKYY-----CPRMNSMNKPAYAAICTHSPTKPVLIFVSSRRQTRLTALD 1603
Query: 257 LAK-KVKNYLDRKELRELRELAESLEENPTNEKLAKALLSGVAFHHAGLGRDERVLVEDN 315
L + + R+ L E + + T++ L L G+ HHAGL +R VE+
Sbjct: 1604 LIQFAASDEHPRQFLSVSEEDLQMVLSQITDQNLRHTLQFGIGLHHAGLNDHDRSAVEEL 1663
Query: 316 FRKGLIKVVVATPTLSAGINTPAFRVIIRDTWRYSEFGMER---IPVLEVQQMMGRAGRP 372
F I+V+V+T TL+ G+N PA VII+ T Y + +R P+ E+ QMMGRAGRP
Sbjct: 1664 FTNNKIQVLVSTSTLAWGVNLPAHLVIIKGT-EYFDGKTKRYVDFPLTEILQMMGRAGRP 1722
Query: 373 RYDEVGEAIIVSTTEEPSLVIDHYIKGKPEKLFSQLSNESILRSQILALIATFGYSEFKE 432
++D+ G+A+I+ EP +P + S L + + T G E
Sbjct: 1723 QFDQHGKAVIL--VHEPKKSFYKKFLYEPFPVESSLKEKLHDHFNAEIVSGTIGNKEDAV 1780
Query: 433 IY---DFLER------TFYAHQGKDPYMLEEKIRRII---YFLLENEFIEVTLEDEIKPL 480
Y +L R +Y +G + + R++ + LE+ ED ++P
Sbjct: 1781 HYLTWTYLFRRLMANPAYYGLEGTQDETICSYLSRLVQTTFEDLEDSGCLKVNEDSVEPT 1840
Query: 481 PLGVRTTKLYIDPMTAKIFKDTLPRIEKNPNPLGIFHMISLAPDLTPLSYSKRETSMLED 540
LG ++ Y+ MT +F I + + H+++ A + L E E+
Sbjct: 1841 MLGTIASQYYLCYMTVSMFGS---NIGPDTSLEAFLHILAGASEYDELPVRHNE----EN 1893
Query: 541 EYYSLMDRLYFELD 554
+L DR+ + +D
Sbjct: 1894 YNKTLSDRVRYPVD 1907
Score = 175 bits (439), Expect = 2e-42
Identities = 136/437 (31%), Positives = 220/437 (50%), Gaps = 44/437 (10%)
Query: 40 ENLLVAIPTASGKTLIAEIAIANKLLEEGG---------KAVYIVPLKALAEEKFREF-K 89
EN+LV PT +GKT IA I++ +++ + K VY+ P+KALA E F +
Sbjct: 524 ENILVCAPTGAGKTNIAMISVLHEIKQHFRDGYLHKNEFKIVYVAPMKALAAEVTSAFSR 583
Query: 90 DWERLGLKVAMATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSSWIRD--VKMLVIDEI 147
L + V TGD L + +I+ T EK+D + R S VK+L+IDE+
Sbjct: 584 RLAPLNMVVKELTGDMQLTKTELEETQMIVTTPEKWDVITRKSSDMSMSMLVKLLIIDEV 643
Query: 148 HLIGSRDRGATLEFIITQMLGRAQ-------IIGLSATIGNPEELAEWLNAKL------I 194
HL+ DRGA +E ++ + L + + I+GLSAT+ + ++A++L
Sbjct: 644 HLLND-DRGAVIEALVARTLRQVESTQTMIRIVGLSATLPSYLQVAQFLRVNTDTGLFYF 702
Query: 195 RSDWRPVKLRKGVFYQGFVFWEDGGSERYNSWEELVY----DAVKKGKGALVFVNMRRKA 250
S +RPV L + Y G E + R E+ Y D++K+G A++FV+ R+
Sbjct: 703 DSSYRPVPLAQQ--YIGIT--EHNFAARNELLNEICYKKVVDSIKQGHQAMIFVHSRKDT 758
Query: 251 EKTALELAKKVKNY----LDRKELRELRELAESLEENPTNEKLAKALLSGVAFHHAGLGR 306
KTA +L + Y L E +L + N+ L K +G HHAG+ R
Sbjct: 759 SKTAEKLVDLARQYETLDLFTNETHPQFQLMKKDVMKSRNKDLVKFFEAGFGIHHAGMLR 818
Query: 307 DERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWRY--SEFGMERIPVLEVQQ 364
+R L E F GL+KV+V T TL+ G+N PA V+I+ T Y G + + +L+V Q
Sbjct: 819 SDRTLTERLFSDGLLKVLVCTATLAWGVNLPAHTVVIKGTQLYDAKAGGWKDLGMLDVMQ 878
Query: 365 MMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKGKPEKLFSQLSNESILRSQILALIAT 424
+ GRAGRP++D+ GE II+++ ++ + +Y++ +L + S L+ + A +
Sbjct: 879 IFGRAGRPQFDKSGEGIIITSHDK----LAYYLRLLTSQLPIESQFISSLKDNLNAEVVL 934
Query: 425 FGYSEFKEIYDFLERTF 441
+ KE +L T+
Sbjct: 935 GTVTNVKEACAWLGYTY 951
>gb|AAC49699.1| (U35242) G9365 ORF [Saccharomyces cerevisiae]
Length = 1967
Score = 185 bits (464), Expect = 2e-45
Identities = 192/698 (27%), Positives = 317/698 (44%), Gaps = 85/698 (12%)
Query: 40 ENLLVAIPTASGKTLIAEIAIANKLLE-EGGKAVYIVPLKALAEEKFREFKDWER----- 93
EN V PT SGKT++AE+AI + G K VYI P+KAL E+ DW +
Sbjct: 1156 ENAFVGSPTGSGKTIVAELAIWHAFKTFPGKKIVYIAPMKALVRERV---DDWRKKITPV 1212
Query: 94 LGLKVAMATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSS--WIRDVKMLVIDEIHLIG 151
G KV TGD + + I+I T EKFD + R+ + +++DV ++++DEIHL+
Sbjct: 1213 TGDKVVELTGDSLPDPKDVHDATIVITTPEKFDGISRNWQTRKFVQDVSLIIMDEIHLLA 1272
Query: 152 SRDRGATLEFIITQM-------LGRAQIIGLSATIGNPEELAEWLNAK-----LIRSDWR 199
S DRG LE I+++M +++G+S + N ++A WL K S R
Sbjct: 1273 S-DRGPILEMIVSRMNYISSQTKQPVRLLGMSTAVSNAYDMAGWLGVKDHGLYNFPSSVR 1331
Query: 200 PVKLRKGV--FYQGFVFWEDGGSERYNSWEELVYDAVKK---GKGALVFVNMRRKAEKTA 254
PV L+ + F F + + V+ A+K+ K AL+FV RR+ TA
Sbjct: 1332 PVPLKMYIDGFPDNLAF-----CPLMKTMNKPVFMAIKQHSPDKPALIFVASRRQTRLTA 1386
Query: 255 LELAK------KVKNYLDRKELRELRELAESLEENPTNEKLAKALLSGVAFHHAGLGRDE 308
L+L + +L+ + EL+ + T++ L +L G+ HHAGL + +
Sbjct: 1387 LDLIHLCGMEDNPRRFLNIDDEEELQYYLSQV----TDDTLKLSLQFGIGLHHAGLVQKD 1442
Query: 309 RVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWRYSE--FGMERIPVLEVQQMM 366
R + F+K I++++AT TL+ G+N PA VII+ T + G + + ++ QMM
Sbjct: 1443 RSISHQLFQKNKIQILIATSTLAWGVNLPAHLVIIKGTQFFDAKIEGYRDMDLTDILQMM 1502
Query: 367 GRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIK-GKPEKLFSQLSNESILRSQILALIATF 425
GRAGRP YD G A IV T E + H++ G P + S +L + A I +
Sbjct: 1503 GRAGRPAYDTTGTA-IVYTKESKKMFYKHFLNVGFP----VESSLHKVLDDHLGAEITSG 1557
Query: 426 GYSEFKEIYDFLERTFY---AHQGKDPYMLEEKIRRIIYFLLENEFIEVTLE-------- 474
+ +E DFL TF AH Y +E+ + I+ TLE
Sbjct: 1558 SITNKQEALDFLSWTFLFRRAHHNPTYYGIEDDTSTAGVSEHLSSLIDSTLENLRESQCV 1617
Query: 475 ----DEIKPLPLGVRTTKLYIDPMTAKIFKDTLPRIEKNPNPLGIFHMISLAPDLTPLSY 530
D+I P ++ YI +T + L +I + + +SLA + L
Sbjct: 1618 LLHGDDIVATPFLSISSYYYISHLT---IRQLLKQIHDHATFQEVLRWLSLAVEYNELPV 1674
Query: 531 SKRETSMLEDEYYSLMDRLYFELDYENERK---FFRAFKTALVLNAWINEV--PEGEIVE 585
R ++ +E S R E + +E + + KT L+L A ++ V P + ++
Sbjct: 1675 --RGGEIIMNEEMSQQSRYSVESTFTDEFELPMWDPHVKTFLLLQAHLSRVDLPIADYIQ 1732
Query: 586 RFNVEPGDIYRIVETAEWLIYSLGEIAKVLEASQEVVDYVNTLRLRVKHGIREELIPLME 645
D +++ + ++ + ++A L V+ + ++ +K G E P+
Sbjct: 1733 -------DTVSVLDQSLRILQAYIDVASELGYFHTVLTMIKMMQC-IKQGYWYEDDPVSV 1784
Query: 646 LPMVGRKRARALYNAGFKDLESIRNAKPSELLRIEGIG 683
LP + +R + + +E K +LL +E IG
Sbjct: 1785 LPGLQLRRIKDYTFSEQGFIEMTPQQKKKKLLTLEEIG 1822
Score = 143 bits (357), Expect = 7e-33
Identities = 138/561 (24%), Positives = 252/561 (44%), Gaps = 73/561 (13%)
Query: 40 ENLLVAIPTASGKTLIAEIAIANKLLE--------------EGGKAVYIVPLKALAEEKF 85
EN+L+ PT +GKT IA + I N + + + K +Y+ PLKALA E
Sbjct: 304 ENMLICAPTGAGKTDIALLTIINTIKQFSVVNGENEIDIQYDDFKVIYVAPLKALAAEIV 363
Query: 86 REF-KDWERLGLKVAMATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSS---WIRDVKM 141
+F K ++V TGD + +I+ T EK+D + R + + VK+
Sbjct: 364 DKFSKKLAPFNIQVRELTGDMQLTKAEILATQVIVTTPEKWDVVTRKANGDNDLVSKVKL 423
Query: 142 LVIDEIHLIGSRDRGATLEFIITQMLGRAQ-------IIGLSATIGNPEELAEWLNAK-- 192
L+IDE+HL+ DRG +E ++ + L + + IIGLSAT+ N ++A++L
Sbjct: 424 LIIDEVHLL-HEDRGPVIETLVARTLRQVESSQSMIRIIGLSATLPNFMDVADFLGVNRQ 482
Query: 193 ----LIRSDWRPVKLRKGVF-YQGFVFWEDGGSERYNSWEELVYDA----VKKGKGALVF 243
+RP L + + +G + G + + +++ YD +++G +VF
Sbjct: 483 IGMFYFDQSFRPKPLEQQLLGCRG----KAGSRQSKENIDKVAYDKLSEMIQRGYQVMVF 538
Query: 244 VNMRRKAEKTALELAKKVKNY----LDRKELRELRELAESLEENPTNEKLAKALLSGVAF 299
V+ R++ K+A K ++ L + E + + SL +N ++ + + G
Sbjct: 539 VHSRKETVKSARNFIKLAESNHEVDLFAPDPIEKDKYSRSLVKN-RDKDMKEIFQFGFGI 597
Query: 300 HHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWRY--SEFGMERI 357
HHAG+ R +R L E F+ G IKV+ T TL+ G+N PA VII+ T Y + G +
Sbjct: 598 HHAGMARSDRNLTEKMFKDGAIKVLCCTATLAWGVNLPADCVIIKGTQVYDSKKGGFIDL 657
Query: 358 PVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKGKPEKLFSQLSNESILRSQ 417
+ +V Q+ GR GRP + I+ T+ + +DHY+ ++ + S L
Sbjct: 658 GISDVIQIFGRGGRPGFGSANGTGILCTSNDR---LDHYVSLITQQHPIESRFGSKLVDN 714
Query: 418 ILALIATFGYSEFKEIYDFLERTF---------------YAHQGKDPYMLEEKIRRIIYF 462
+ A I+ + E ++L T+ + DP + E + + I+
Sbjct: 715 LNAEISLGSVTNVDEAIEWLGYTYMFVRMRKNPFTYGIDWEEIANDPQLYERRRKMIVVA 774
Query: 463 LLENEFIEVTLEDEIK----PLPLGVRTTKLYIDPMTAKIFKDTLPRIEKNPNPLGIFHM 518
+++ + DE+ LG ++ Y+ + +IF + + M
Sbjct: 775 ARRLHALQMIVFDEVSMHFIAKDLGRVSSDFYLLNESVEIFNQ---MCDPRATEADVLSM 831
Query: 519 ISLAPDLTPLSYSKRETSMLE 539
IS++ + + + + E+ L+
Sbjct: 832 ISMSSEFDGIKFREEESKELK 852
>dbj|BAB14906.1| (AK024391) unnamed protein product [Homo sapiens]
Length = 1811
Score = 184 bits (463), Expect = 2e-45
Identities = 167/570 (29%), Positives = 267/570 (46%), Gaps = 60/570 (10%)
Query: 16 LRERGIEELY--------PPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLEE 67
LR E LY P Q + + +N+ V PT SGKT+ AE AI LL+
Sbjct: 987 LRNSAFESLYRDKFPFFNPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQS 1046
Query: 68 G-GKAVYIVPLKALAEEKFREF--KDWERLGLKVAMATGDYDSKDEWLGKYDIIIATAEK 124
G+ VYI P++ALAE+ + ++ K +RL KV + TG+ + + LGK +III+T EK
Sbjct: 1047 SEGRCVYITPMEALAEQVYMDWYEKFQDRLNKKVVLLTGETSTDLKLLGKGNIIISTPEK 1106
Query: 125 FDSLLRHGSSW--IRDVKMLVIDEIHLIGSRDRGATLEFIITQMLGRA-------QIIGL 175
+D L R ++++ + V+DE+HLIG + G LE I ++M + +I+ L
Sbjct: 1107 WDILSRRWKQRKNVQNINLFVVDEVHLIGG-ENGPVLEVICSRMRNISSQIERPIRIVAL 1165
Query: 176 SATIGNPEELAEWLNAKLIRS-----DWRPVKLRKGVFYQGFVFWEDGGSERYNSWEELV 230
S+++ N +++A WL + + RPV L + QGF R S + V
Sbjct: 1166 SSSLSNAKDVAHWLGCSATSTFNFHPNVRPVPLELHI--QGFNISHT--QTRLLSMAKPV 1221
Query: 231 YDAVKKG---KGALVFVNMRRKAEKTALELAKKVKNYLDRKELRELRE--LAESLEENPT 285
Y A+ K K +VFV R++ TA+++ + R+ E L LE+ +
Sbjct: 1222 YHAITKHSPKKPVIVFVPSRKQTRLTAIDILTTCAADIQRQRFLHCTEKDLIPYLEKL-S 1280
Query: 286 NEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRD 345
+ L + LL+GV + H GL ER LVE F G I+VVVA+ +L G+N A VII D
Sbjct: 1281 DSTLKETLLNGVGYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMD 1340
Query: 346 TWRYSE--FGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKGKPEK 403
T Y+ P+ +V QM+G A RP D+ G +I+ + D + K E
Sbjct: 1341 TQYYNGKIHAYVDYPIYDVLQMVGHANRPLQDDEGRCVIMCQGSKK----DFFKKFLYEP 1396
Query: 404 LFSQLSNESILRSQILALIATFGYSEFKEIYDFLERTF-YAHQGKDPYM----------- 451
L + + + A I T ++ D+L TF Y ++P
Sbjct: 1397 LPVESHLDHCMHDHFNAEIVTKTIENKQDAVDYLTWTFLYRRMTQNPNYYNLQGISHRHL 1456
Query: 452 ---LEEKIRRIIYFLLENEFIEVTLEDEIKPLPLGVRTTKLYIDPMTAKIFKDTLPRIEK 508
L E + + + L +++ I + E ++ PL LG+ YI+ T ++F +L
Sbjct: 1457 SDHLSELVEQTLSDLEQSKCISIEDEMDVAPLNLGMIAAYYYINYTTIELFSMSL---NA 1513
Query: 509 NPNPLGIFHMISLAPDLTPLSYSKRETSML 538
G+ +IS A + + E ++L
Sbjct: 1514 KTKVRGLIEIISNAAEYENIPIRHHEDNLL 1543
Score = 169 bits (425), Expect = 7e-41
Identities = 131/404 (32%), Positives = 211/404 (51%), Gaps = 40/404 (9%)
Query: 20 GIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLE----------EGG 69
G + L Q++ + + ENLL+ PT +GKT +A + + ++ + +
Sbjct: 152 GFKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDF 211
Query: 70 KAVYIVPLKALAEEKFREF-KDWERLGLKVAMATGDYDSKDEWLGKYDIIIATAEKFDSL 128
K +YI P+++L +E F K G+ VA TGD+ E + II+ T EK+D +
Sbjct: 212 KIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDII 271
Query: 129 LRHGS--SWIRDVKMLVIDEIHLIGSRDRGATLEFIITQMLGRAQ-------IIGLSATI 179
R G ++ + V+++++DEIHL+ DRG LE ++ + + + +IGLSAT+
Sbjct: 272 TRKGGERTYTQLVRLIILDEIHLLHD-DRGPVLEALVARAIRNIEMTQEDVRLIGLSATL 330
Query: 180 GNPEELAEWLNAKLIR------SDWRPVKLRKGVFYQGFVFWEDGGSERYNSWEELVYDA 233
N E++A +L + + +RPV L + Y G E +R+ E+VY+
Sbjct: 331 PNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQT--YVGIT--EKKAIKRFQIMNEIVYEK 386
Query: 234 VKKGKG---ALVFVNMRRKAEKTALELA----KKVKNYLDRKELRELRELAESLEENPTN 286
+ + G LVFV+ R++ KTA + +K L +E E+ + E N
Sbjct: 387 IMEHAGKNQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKN 446
Query: 287 EKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDT 346
+L L G A HHAG+ R +R LVED F I+V+V+T TL+ G+N PA VII+ T
Sbjct: 447 LELKDLLPYGFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGT 506
Query: 347 WRYS-EFG-MERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEE 388
YS E G + L++ QM+GRAGRP+YD GE I++++ E
Sbjct: 507 QVYSPEKGHWTELGALDILQMLGRAGRPQYDTKGEGILITSHGE 550
>dbj|BAA34508.1| (AB018331) KIAA0788 protein [Homo sapiens]
Length = 1324
Score = 184 bits (462), Expect = 3e-45
Identities = 167/570 (29%), Positives = 267/570 (46%), Gaps = 60/570 (10%)
Query: 16 LRERGIEELY--------PPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLEE 67
LR E LY P Q + + +N+ V PT SGKT+ AE AI LL+
Sbjct: 500 LRNSAFESLYQDKFPFFNPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQS 559
Query: 68 G-GKAVYIVPLKALAEEKFREF--KDWERLGLKVAMATGDYDSKDEWLGKYDIIIATAEK 124
G+ VYI P++ALAE+ + ++ K +RL KV + TG+ + + LGK +III+T EK
Sbjct: 560 SEGRCVYITPMEALAEQVYMDWYEKFQDRLNKKVVLLTGETSTDLKLLGKGNIIISTPEK 619
Query: 125 FDSLLRHGSSW--IRDVKMLVIDEIHLIGSRDRGATLE-------FIITQMLGRAQIIGL 175
+D L R ++++ + V+DE+HLIG + G LE +I +Q+ +I+ L
Sbjct: 620 WDILSRRWKQRKNVQNINLFVVDEVHLIGG-ENGPVLEVICSRMRYISSQIERPIRIVAL 678
Query: 176 SATIGNPEELAEWLNAKLIRS-----DWRPVKLRKGVFYQGFVFWEDGGSERYNSWEELV 230
S+++ N +++A WL + + RPV L + QGF R S + V
Sbjct: 679 SSSLSNAKDVAHWLGCSATSTFNFHPNVRPVPLELHI--QGFNISHT--QTRLLSMAKPV 734
Query: 231 YDAVKKG---KGALVFVNMRRKAEKTALELAKKVKNYLDRKELRELRE--LAESLEENPT 285
Y A+ K K +VFV R++ TA+++ + R+ E L LE+ +
Sbjct: 735 YHAITKHSPKKPVIVFVPSRKQTRLTAIDILTTCAADIQRQRFLHCTEKDLIPYLEKL-S 793
Query: 286 NEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRD 345
+ L + LL+GV + H GL ER LVE F G I+VVVA+ +L G+N A VII D
Sbjct: 794 DSTLKETLLNGVGYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMD 853
Query: 346 TWRYSE--FGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKGKPEK 403
T Y+ P+ +V QM+G A RP D+ G +I+ + D + K E
Sbjct: 854 TQYYNGKIHAYVDYPIYDVLQMVGHANRPLQDDEGRCVIMCQGSKK----DFFKKFLYEP 909
Query: 404 LFSQLSNESILRSQILALIATFGYSEFKEIYDFLERTF-YAHQGKDPYM----------- 451
L + + + A I T ++ D+L TF Y ++P
Sbjct: 910 LPVESHLDHCMHDHFNAEIVTKTIENKQDAVDYLTWTFLYRRMTQNPNYYNLQGISHRHL 969
Query: 452 ---LEEKIRRIIYFLLENEFIEVTLEDEIKPLPLGVRTTKLYIDPMTAKIFKDTLPRIEK 508
L E + + + L +++ I + E ++ PL LG+ YI+ T ++F +L
Sbjct: 970 SDHLSELVEQTLSDLEQSKCISIEDEMDVAPLNLGMIAAYYYINYTTIELFSMSL---NA 1026
Query: 509 NPNPLGIFHMISLAPDLTPLSYSKRETSML 538
G+ +IS A + + E ++L
Sbjct: 1027 KTKVRGLIEIISNAAEYENIPIRHHEDNLL 1056
>emb|CAB60351.1| (AL110485) contains similarity to Pfam domain: PF00270 (DEAD/DEAH
box helicase), Score=204.5, E-value=3.2e-64, N=2~cDNA
EST yk45c4.3 comes from this gene~cDNA EST yk25a5.3
comes from this gene~cDNA EST yk34b6.3 comes from this
gene~cDNA EST yk35b7.3 co>
Length = 2145
Score = 182 bits (456), Expect = 2e-44
Identities = 148/456 (32%), Positives = 229/456 (49%), Gaps = 43/456 (9%)
Query: 20 GIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIA----IANKLLEEGG------ 69
G + L Q+ S + E+LL+ PT +GKT +A + I N L E+G
Sbjct: 471 GYKSLNRIQSRLCDSALRSKEHLLLCAPTGAGKTNVALLTMLQEIGNHLAEDGSVKLDEF 530
Query: 70 KAVYIVPLKALAEEKFREF-KDWERLGLKVAMATGDYDSKDEWLGKYDIIIATAEKFDSL 128
K VYI P+K+L +E F K G+ V TGD E +I+ T EK+D +
Sbjct: 531 KIVYIAPMKSLVQEMVGSFSKRLAPFGITVGEMTGDAQMSKEQFMATQVIVCTPEKYDVV 590
Query: 129 LRHGS--SWIRDVKMLVIDEIHLIGSRDRGATLEFIITQMLGRAQ-------IIGLSATI 179
R G ++ + V++L+IDEIHL+ DRG LE I+ + + + + ++GLSAT+
Sbjct: 591 TRKGGERAYNQMVRLLIIDEIHLLHD-DRGPVLESIVVRTIRQMEQNHDECRLVGLSATL 649
Query: 180 GNPEELAEWLNAK-----LIRSDWRPVKLRKGVFYQGFVFWEDGGSERYNSWEELVYDAV 234
N +++A +L K + +RPV L + Y G E +R+ + E+VYD +
Sbjct: 650 PNYQDVATFLRVKPEHLHFFDNSYRPVPLEQQ--YIGVT--EKKALKRFQAMNEVVYDKI 705
Query: 235 KKGKG---ALVFVNMRRKAEKTALEL--AKKVKNYLDR--KELRELRELAESLEENPTNE 287
+ G LVFV+ R++ KTA + A K+ L +E E+ + E N
Sbjct: 706 MEHAGKSQVLVFVHSRKETAKTAKAIRDACLEKDTLSAFMREGSASTEILRTEAEQAKNL 765
Query: 288 KLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTW 347
L L G A HHAG+ R +R LVED F I+V+ +T TL+ G+N PA VII+ T
Sbjct: 766 DLKDLLPYGFAIHHAGMNRVDRTLVEDLFADRHIQVLFSTATLAWGVNLPAHTVIIKGTQ 825
Query: 348 RYS-EFG-MERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKGKPEKLF 405
Y+ E G + L++ QM+GRAGRP+YD+ GE I+++ E + +Y+ ++L
Sbjct: 826 IYNPEKGRWTELGALDIMQMLGRAGRPQYDDRGEGILITNHSE----LQYYLSLMNQQLP 881
Query: 406 SQLSNESILRSQILALIATFGYSEFKEIYDFLERTF 441
+ S L + A + S E ++L TF
Sbjct: 882 VESQMVSRLTDMLNAEVVLGTVSSVSEATNWLGYTF 917
Score = 133 bits (332), Expect = 6e-30
Identities = 164/727 (22%), Positives = 314/727 (42%), Gaps = 87/727 (11%)
Query: 9 SEKIKEILRERGIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLE-E 67
+++ + + E G + P Q + + EN++V P SGKT IAE+A+
Sbjct: 1307 NKEFQTVFAESGFKVFNPIQTQVFRTVFESNENVIVCAPNGSGKTAIAELAVLRHFENTP 1366
Query: 68 GGKAVYIVPLKALAEEKFREFKDWER-----LGLKVAMATGDYDSKDEWLGKYDIIIATA 122
KAVYI P++ +A + + DW+R +G + + TG+ + + +II+T
Sbjct: 1367 EAKAVYITPMEDMAT---KVYADWKRRLEPAIGHTIVLLTGEQTMDLKLAQRGQLIISTP 1423
Query: 123 EKFDSLLRHGS--SWIRDVKMLVIDEIHLIGSRDRGATLE-------FIITQMLGRAQII 173
E++D++ R +++VK+ + D++H+IG+ GA E +I +Q+ +++
Sbjct: 1424 ERWDNISRRWKQRKSVQNVKLFIADDLHMIGA-SNGAVFEVVCSRTRYISSQLESAVRVV 1482
Query: 174 GLSATIGNPEELAEWLNAKL-----IRSDWRPVKLRKGVFYQGFVFWEDGGSERYNSWEE 228
LS+++ N +L WL RPV L + F + R+ + E
Sbjct: 1483 ALSSSLTNARDLGMWLGCSASATFNFMPSTRPVPLDLEI----KSFNLSHNASRFAAMER 1538
Query: 229 LVYDAVKKGKG------ALVFVNMRRKAEKTALELAKKV------KNYLDRKELRELREL 276
VY A+ + G ALVFV +RR+ A+ L K +L L E +
Sbjct: 1539 PVYQAICRHAGKLEPKPALVFVPVRRQTRPVAVALLTMALADGAPKRFL---RLAEHDDT 1595
Query: 277 AESLEENPTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINT 336
++L + +E L +++ GV F H G + +V+ F I+V V + I
Sbjct: 1596 FQALLADIEDESLRESVSCGVGFLHEGTAPKDVHIVQQLFESNAIQVCVVPRGMCYQIEM 1655
Query: 337 PAFRVIIRDTWRYS--EFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVID 394
A+ V++ DT Y+ E P+ ++ M+G A RP D + +++ T + +
Sbjct: 1656 SAYLVVVMDTQFYNGKYHVYEDYPIADMLHMVGLANRPILDSDAKCVVMCQTSKRA---- 1711
Query: 395 HYIKGKPEKLFSQLSNESILRSQILALIATFGYSEFKEIYDFLERT-FYAHQGKDP--YM 451
+Y K + L + + L A I T ++ D+L T Y ++P Y
Sbjct: 1712 YYKKFLCDPLPVESHLDHCLHDHFNAEIVTKTIENKQDAIDYLTWTLLYRRMTQNPNYYN 1771
Query: 452 LEEKIRRIIYFLLENEFIEVTLED-------------EIKPLPLGVRTTKLYIDPMTAKI 498
L+ R + L +E +E+TL+D + L LG+ + YI T ++
Sbjct: 1772 LQGTTHRHLSDAL-SELVELTLKDLENSKCIAVKDEMDTVSLNLGMIASYYYISYQTIEL 1830
Query: 499 FKDTLPRIEKNPNPLGIFHMISLAPDLTPLSYSKRETSMLEDEYYSLMDRLYFELDYENE 558
F +L ++ + +IS + + + +E +L L +RL +L +N+
Sbjct: 1831 FSMSL---KEKTKTRALIEIISASSEFGNVPMRHKEDVILR----QLAERLPGQL--KNQ 1881
Query: 559 RKFFRAFKTALVLNAWINEVPEGEIVERFNVEPGDIY----RIVETAEWLIYSLGEIAKV 614
+ K L+++A ++ V ++ N + I R+V+ ++ S G ++
Sbjct: 1882 KFTDPHVKVNLLIHAHLSRV---KLTAELNKDTELIVLRACRLVQACVDVLSSNGWLSPA 1938
Query: 615 LEASQEVVDYVNTLRLRVKHGIREELIPLMELPMVGRKRARALYNAGFKDLESIRNAKPS 674
+ A + ++ + + + L L +RA+A +L + N S
Sbjct: 1939 IHAME-----LSQMLTQAMYSNEPYLKQLPHCSAALLERAKAKEVTSVFELLELENDDRS 1993
Query: 675 ELLRIEG 681
++L++EG
Sbjct: 1994 DILQMEG 2000
>gi|6321020 putative ATP-dependent RNA helicase; Brr2p [Saccharomyces cerevisiae]
>gi|731380|sp|P32639|BRR2_YEAST PRE-MRNA SPLICING
HELICASE BRR2 >gi|1077724|pir||S50675 pre-mRNA splicing
helicase BRR2 - yeast (Saccharomyces cerevisiae)
>gi|603413|gb|AAB64699.1| (U18922) Brr2p: Putative
ATP-dependent RNA helicase [Saccharomyces cerevisiae]
>gi|1699380|gb|AAB37500.1| Rss1p=ATP-dependent RNA
helicase homolog [Saccharomyces cerevisiae, Peptide
Mutant, 2163 aa]
Length = 2163
Score = 181 bits (455), Expect = 2e-44
Identities = 162/579 (27%), Positives = 272/579 (45%), Gaps = 84/579 (14%)
Query: 24 LYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAI-----------ANKLLEEGGKAV 72
L P Q++ + N+L+ PT SGKT IA + + KL K V
Sbjct: 499 LNPIQSKVFHAAFEGDSNMLICAPTGSGKTNIALLTVLKALSHHYNPKTKKLNLSAFKIV 558
Query: 73 YIVPLKALAEEKFREF-KDWERLGLKVAMATGDYDSKDEWLGKYDIIIATAEKFDSLLRH 131
YI PLKAL +E+ REF + LG+KVA TGD + + + ++++T EK+D R+
Sbjct: 559 YIAPLKALVQEQVREFQRRLAFLGIKVAELTGDSRLSRKQIDETQVLVSTPEKWDITTRN 618
Query: 132 GSSW--IRDVKMLVIDEIHLIGSRDRGATLEFIITQMLGRAQ-------IIGLSATIGNP 182
++ + V++L+IDEIHL+ DRG LE I+ + ++ IIGLSAT+ N
Sbjct: 619 SNNLAIVELVRLLIIDEIHLLHD-DRGPVLESIVARTFWASKYGQEYPRIIGLSATLPNY 677
Query: 183 EELAEWLNAKLIRSDWRPVKLRKGVFYQGFVFWEDGGSERY------NSWEEL------- 229
E++ +L ++G+FY F S+++ NS ++L
Sbjct: 678 EDVGRFLRVP-----------KEGLFYFDSSFRPCPLSQQFCGIKERNSLKKLKAMNDAC 726
Query: 230 ---VYDAVKKGKGALVFVNMRRKAEKTALELAKK-----VKNYLDRKELRELRELAESLE 281
V +++ +G +VFV+ R++ +TA L K + + L + + +++ ++
Sbjct: 727 YEKVLESINEGNQIIVFVHSRKETSRTATWLKNKFAEENITHKLTKNDAGS-KQILKTEA 785
Query: 282 ENPTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRV 341
N + L K + SG+ HHAGL R +R L ED F GL++V+V T TL+ G+N PA V
Sbjct: 786 ANVLDPSLRKLIESGIGTHHAGLTRSDRSLSEDLFADGLLQVLVCTATLAWGVNLPAHTV 845
Query: 342 IIRDTWRYS--EFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKG 399
II+ T YS + E++ +V QM+GRAGRPRYD GE II++ + +Y+
Sbjct: 846 IIKGTDVYSPEKGSWEQLSPQDVLQMLGRAGRPRYDTFGEGIIITDQSN----VQYYLSV 901
Query: 400 KPEKLFSQLSNESILRSQILALIATFGYSEFKEIYDFLERTF-YAHQGKDPYML------ 452
++L + S L + A + + ++L T+ Y P +
Sbjct: 902 LNQQLPIESQFVSKLVDNLNAEVVAGNIKCRNDAVNWLAYTYLYVRMLASPMLYKVPDIS 961
Query: 453 ---------EEKIRRIIYFLLENEFIEVTLE-DEIKPLPLGVRTTKLYIDPMTAKIFKDT 502
E + + L E E + E D I+ LG + YI+ + ++
Sbjct: 962 SDGQLKKFRESLVHSALCILKEQELVLYDAENDVIEATDLGNIASSFYINHASMDVYNRE 1021
Query: 503 LPRIEKNPNPLGIFHMISLAPDLTPLSY---SKRETSML 538
L +++ + +F + S++ + +S KRE L
Sbjct: 1022 L---DEHTTQIDLFRIFSMSEEFKYVSVRYEEKRELKQL 1057
>sp|P51979|HFM1_YEAST HFM1 PROTEIN >gi|780546|gb|AAA93159.1| (U22156) Hfm1p
[Saccharomyces cerevisiae]
Length = 1048
Score = 179 bits (450), Expect = 8e-44
Identities = 152/479 (31%), Positives = 237/479 (48%), Gaps = 44/479 (9%)
Query: 28 QAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLEEGG-----KAVYIVPLKALAE 82
Q+EA S EN +++ PT SGKT++ E+AI + E K +YI P K+L
Sbjct: 2 QSEAFPSIYESNENCIISSPTGSGKTVLFELAILRLIKETNSDTNNTKIIYIAPTKSLCY 61
Query: 83 EKFREFKDW--ERLGLKVAMATGDYDSKD-EWLGKYDIIIATAEKFDSLLRHGSSWIRD- 138
E + K+W + L V M T D + E K +III T EK+D L R S + R
Sbjct: 62 EMY---KNWFPSFVNLSVGMLTSDTSFLETEKAKKCNIIITTPEKWDLLTRRWSDYSRLF 118
Query: 139 --VKMLVIDEIHLIGSRDRGATLEFIITQMLGRAQ---IIGLSATIGNPEELAEWLN--- 190
VK++++DEIH I + RGA+LE I+T+M Q + LSAT+ N E+LA WL
Sbjct: 119 ELVKLVLVDEIHTIKEK-RGASLEVILTRMNTMCQNIRFVALSATVPNIEDLALWLKTNN 177
Query: 191 ---AKLIRSD--WRPVKLRKGVFYQGFVFWEDGGSER-YNSWEELVYDAVKKGKGALVFV 244
A ++ D +R V+L K V+ F D + YNS + + + L+F
Sbjct: 178 ELPANILSFDESYRQVQLTKFVYGYSFNCKNDFQKDAIYNSKLIEIIEKHADNRPVLIFC 237
Query: 245 NMRRKAEKTALELAKKVKNYLDRKELRELRELAESLEENPTNEKLAKALLSGVAFHHAGL 304
R TA L + N++ K + NP+++ L + + G+AFHHAG+
Sbjct: 238 PTRASTISTAKFL---LNNHIFSKSKKRCNH-------NPSDKILNECMQQGIAFHHAGI 287
Query: 305 GRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWRYSEFGMERIPVLEVQQ 364
++R VE F G I ++ +T TL+ G+N PA+ VII+ T ++ ++ L+V Q
Sbjct: 288 SLEDRTAVEKEFLAGSINILCSTSTLAVGVNLPAYLVIIKGTKSWNSSEIQEYSDLDVLQ 347
Query: 365 MMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKGKPEKLFSQLSNESILRSQILALIAT 424
M+GRAGRP+++ G A+I+ T + ++ I G + L S L I + T
Sbjct: 348 MIGRAGRPQFETHGCAVIM-TDSKMKQTYENLIHG-TDVLESSLHLNLIEHLAAETSLET 405
Query: 425 FGYSEFKEIYDFLERT-FYAHQGKDPYMLEEKIRRIIYFLLE----NEFIEVTLEDEIK 478
E ++L T FY GK+P +E R + + +E N+F + L+ +K
Sbjct: 406 VYSIETAAAVNWLRNTFFYVRFGKNPAAYQEVNRYVSFHSVEDSQINQFCQYLLDTLVK 464
>gb|AAF55204.1| (AE003709) CG5205 gene product [Drosophila melanogaster]
Length = 1809
Score = 179 bits (449), Expect = 1e-43
Identities = 131/376 (34%), Positives = 203/376 (53%), Gaps = 37/376 (9%)
Query: 41 NLLVAIPTASGKTLIAEIAIANKLLEEGG-KAVYIVPLKALAEEKFREFKDWER------ 93
N+L+ PT SGKT++AEIAI L + K VYI PLKAL +E+ DWE+
Sbjct: 980 NVLLGAPTGSGKTIVAEIAIFRALNQNPKCKVVYIAPLKALVKERIA---DWEQRFQRSS 1036
Query: 94 LGLKVAMATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSS--WIRDVKMLVIDEIHLIG 151
LGLKV TGD + + + +I+ T EK+D + R + +++ V ++VIDEIHL+G
Sbjct: 1037 LGLKVVELTGDVTPDIQAIRESQLIVTTPEKWDGISRSWQTREYVQHVSLIVIDEIHLLG 1096
Query: 152 SRDRGATLEFIITQM------LGRA-QIIGLSATIGNPEELAEWLNAKLI-----RSDWR 199
DRG +E I+++ GRA +I+GLS + N ++LA WL + + R
Sbjct: 1097 E-DRGPVIEVIVSRTNFISSHTGRAIRIVGLSTALANAQDLANWLGINKMGLYNFKPSVR 1155
Query: 200 PVKLRKGVFYQGFVFWEDGGSERYNSWEELVYDAVKKG---KGALVFVNMRRKAEKTALE 256
PV L+ V GF R + + A++ + +VFV+ RR+ TAL+
Sbjct: 1156 PVPLQ--VHINGFP--GKHYCPRMATMNRPTFQAIRTYSPCEPTIVFVSSRRQTRLTALD 1211
Query: 257 LAKKVKNYLDRKELRELRE-LAESLEENPTNEKLAKALLSGVAFHHAGLGRDERVLVEDN 315
L V + K+ + E E + +N + L L G+ HHAGL +R VE+
Sbjct: 1212 LITFVAGESNPKQFLHIPEDEIELILQNIREQNLKFCLAFGIGLHHAGLQEQDRKCVEEL 1271
Query: 316 FRKGLIKVVVATPTLSAGINTPAFRVIIRDTWRYSEFGMER---IPVLEVQQMMGRAGRP 372
F I+++VAT TL+ G+N PA V+I+ T Y + +++ +P+ +V QMMGRAGRP
Sbjct: 1272 FLNRKIQILVATATLAWGVNLPAHLVVIKGT-EYFDGKVKKYVDMPITDVLQMMGRAGRP 1330
Query: 373 RYDEVGEAIIVSTTEE 388
++D G A+++ E+
Sbjct: 1331 QFDNEGVAVVLVHDEK 1346
Score = 150 bits (376), Expect = 4e-35
Identities = 129/416 (31%), Positives = 210/416 (50%), Gaps = 45/416 (10%)
Query: 40 ENLLVAIPTASGKTLIAEIAIANKL---LEEGG------KAVYIVPLKALAEEKFREF-K 89
EN+LV PT +GKT +A ++I + + LE+G K VYI P+KALA E F K
Sbjct: 129 ENMLVCAPTGAGKTNVAMLSIVHTIRCHLEQGVINRDEFKIVYIAPMKALAAEMVDNFSK 188
Query: 90 DWERLGLKVAMATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGS---SWIRDVKMLVIDE 146
+ L + V TGD + I++ T EK+D + R GS + I V++L+IDE
Sbjct: 189 RLKSLQIAVRELTGDIQLTKAEMAATQILVTTPEKWDVVTRKGSGDVALISLVELLIIDE 248
Query: 147 IHLIGSRDRGATLEFIITQML-------GRAQIIGLSATIGNPEELAEWLNAKLIR---- 195
+HL+ +RG +E ++ + L +I+GLSAT+ N ++A +L ++
Sbjct: 249 VHLLHG-ERGPVVEALVARTLRLVESSQSMIRIVGLSATLPNYIDVAHFLRVNPMKGLFY 307
Query: 196 --SDWRPVKLRKGVFYQGFVFWEDGGSERYNSWEELVYDAVKKGKGALVFVNMRRKAEKT 253
S +RPV L V ++ + + V++G +VFV+ R +T
Sbjct: 308 FDSRFRPVPLDTNFVGIKSVKQLQQIADMDQCCYQKCVEMVQEGHQIMVFVHARNATVRT 367
Query: 254 A---LELAKKVK-NYLDRKELRELRELAESLEENPTNEKLAKALLSGVAFHHAGLGRDER 309
A ELA++ + L + LA + N++L + G+A HHAG+ R +R
Sbjct: 368 ANVIRELAQQNNTSALFLPKDSAAHGLATRSIQRSRNKQLVELFSCGLAMHHAGMLRADR 427
Query: 310 VLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWRY--SEFGMERIPVLEVQQMMG 367
+VE F +G I V+V T TL+ G+N PA VIIR T Y + +L+V Q+ G
Sbjct: 428 QMVEKYFVEGHISVLVCTATLAWGVNLPAHAVIIRGTDIYDAKHGSFVDLGILDVLQIFG 487
Query: 368 RAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKGKPEKLFSQLSNESILRSQILALIA 423
RAGRP++D+ G I+++ ++ ++HY+ S L+N+ + S + +A
Sbjct: 488 RAGRPQFDKSGVGTIITSYDK----LNHYL--------SLLTNQFPIESNFVNCLA 531
>pir||T27149 hypothetical protein Y54E2A.6 - Caenorhabditis elegans
>gi|3881104|emb|CAA21682.1| (AL032646) contains
similarity to Pfam domain: PF00270 (DEAD/DEAH box
helicase), Score=243.2, E-value=1.9e-76, N=2~cDNA EST
CEMSC91F comes from this gene~cDNA EST yk36e11.3 comes
from this gene~cDNA EST yk42a9.3 comes from this
gene~cDNA EST yk42a9.5 c>
Length = 1798
Score = 179 bits (449), Expect = 1e-43
Identities = 167/530 (31%), Positives = 256/530 (47%), Gaps = 71/530 (13%)
Query: 26 PPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLEEGG-KAVYIVPLKALAEEK 84
P QA+ ++ L+ PT SGKTL AE+A+ L + G K VYI PLK+L E+
Sbjct: 963 PIQAQVFFCLYKTDKSALIGAPTGSGKTLCAELAMFRLLQDHPGMKVVYIAPLKSLVRER 1022
Query: 85 FREFKDW--ERLGLKVAMATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSS--WIRDVK 140
++K + +G +V +GD E L I+I T EK+D + R ++ ++R V
Sbjct: 1023 VDDWKKKFEDGMGYRVVEVSGDVTPDPEELAASSILITTPEKWDGISRSWATREYVRRVG 1082
Query: 141 MLVIDEIHLIGSRDRGATLEFIITQ--MLGR--------AQIIGLSATIGNPEELAEWLN 190
++V+DE+HL+G DRGA LE I+++ M+ R +++GLS + N ++AEWL
Sbjct: 1083 LIVLDEVHLLGV-DRGAVLEAIVSRLKMITRRSHVTEEPVRLLGLSTALANAGDVAEWLG 1141
Query: 191 AK-----LIRSDWRPVKLRKGVFYQGFVFWEDGGSERYNSWEELVYDAV---KKGKGALV 242
R RPV + V QGF R + Y A+ K L+
Sbjct: 1142 IPDEACYNFRPSVRPVPI--SVHIQGFP--GQHYCPRMGLMNKPAYKAILTYSPRKPVLI 1197
Query: 243 FVNMRRKAEKTALELAKKV------KNYLDRKELRELRELAESLEENPTNEKLAKALLSG 296
FV+ RR+ TAL + K +L+ ++ EL +L ++++ E L L G
Sbjct: 1198 FVSSRRQTRLTALAFVNLLIADHNPKQWLNM-DMLELEDLMAAIKD----ENLKLTLPFG 1252
Query: 297 VAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDT-------WRY 349
+ HHAGL ER +VE F + I+V++AT TL+ GIN PA VI++ T +Y
Sbjct: 1253 IGMHHAGLSAHERAIVEQLFIEKKIQVLIATATLAWGINCPAHLVIVKGTEYFDGKKGKY 1312
Query: 350 SEFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKGKPEKLFSQLS 409
+F PV +V QMMGRAGRP++D+ A+I + + Y K E + S
Sbjct: 1313 VDF-----PVTDVLQMMGRAGRPQFDDSAVAVIYVQDAKKTF----YKKFLYEPFPVESS 1363
Query: 410 NESILRSQILALIATFGYSEFKEIYDFLERTF-YAHQGKDP--YMLEEK--------IRR 458
+L + + A I+ + I ++L +T+ Y +P Y LEE I +
Sbjct: 1364 LLPVLPNHVNAEISAGTIDSKQAIVEYLSKTYLYRRLFANPNYYGLEEDSEEAMLKFITK 1423
Query: 459 I----IYFLLENEFIEVTLE-DEIKPLPLGVRTTKLYIDPMTAKIFKDTL 503
I + LL +E I V E D IKP P G + Y+ T + +L
Sbjct: 1424 IVDDSVAELLASECIHVDSEQDVIKPTPCGRIASVYYLQHETVRFLVKSL 1473
Score = 159 bits (399), Expect = 8e-38
Identities = 134/423 (31%), Positives = 213/423 (49%), Gaps = 56/423 (13%)
Query: 19 RGIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKL----------LEEG 68
+G E+L Q+ ENLL+ PT +GKT IA + I N + +++
Sbjct: 88 KGFEKLNVIQSIVFEQAYKTKENLLICAPTGAGKTNIAMLTILNTIHEHQNSRGDIMKDD 147
Query: 69 GKAVYIVPLKALAEEKFREF-KDWERLGLKVAMATGDYDSKDEWLGKYDIIIATAEKFDS 127
K +YI P+KALA E F K LGLKV TGD + +++ T EK+D
Sbjct: 148 FKIIYIAPMKALATEMTESFGKRLAPLGLKVKELTGDTQLSRNEVADTQMLVLTPEKWDV 207
Query: 128 LLRHGSS---WIRDVKMLVIDEIHLIGSRDRGATLEFIITQMLGRAQ-------IIGLSA 177
+ R +S I V++L+IDE+HL+ +RG +E ++ + L + + I+GLSA
Sbjct: 208 ITRKSTSDNSLINVVRLLIIDEVHLLHD-ERGPVIETLVARTLRQVEMSQSGIRIVGLSA 266
Query: 178 TIGNPEELAEWLNAKLIRS------DWRPVKLRKGVFYQGFVFWEDGGSERYN------- 224
T+ N ++A +L + +RPV L Q F+ G+ R N
Sbjct: 267 TLPNFIDVARFLRVNPYKGLFFFDGRFRPVPLT-----QKFIGTRKAGNFRDNLTLMDNV 321
Query: 225 SWEELVYDAVKKGKGALVFVNMRRKAEKTALELAKKVKNYLDRKELRELRELAESL---E 281
++E+V D VK+G LVFV+ R K + + L + +L ++ A S
Sbjct: 322 CYDEVV-DFVKRGHQVLVFVHTRNGTAKLGEAFCARA-SVLGQMDLFLPKDRASSKYIQA 379
Query: 282 ENPTNEKLAKALLS-----GVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINT 336
+ N +A +S G+ HHAGL R +R+L+E F +G + V+ T TL+ G+N
Sbjct: 380 DKAINICRNRAQISPLFQRGMGIHHAGLCRQDRILMERCFAEGHVSVLFCTATLAWGVNL 439
Query: 337 PAFRVIIRDTWRY-SEFGM-ERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVID 394
PA V+I+ T + +E G+ + VL+VQQ+ GRAGRP+++ G II++T ++ ID
Sbjct: 440 PAHAVVIKGTDVFDAEKGVFTDLGVLDVQQIFGRAGRPQFENEGHGIIITTRDK----ID 495
Query: 395 HYI 397
Y+
Sbjct: 496 KYL 498
>pir||T39411 RNA helicase - fission yeast (Schizosaccharomyces pombe)
>gi|3080535|emb|CAA18663.1| (AL022600) DEAD box helicase
[Schizosaccharomyces pombe]
Length = 1935
Score = 178 bits (448), Expect = 1e-43
Identities = 139/434 (32%), Positives = 218/434 (50%), Gaps = 51/434 (11%)
Query: 41 NLLVAIPTASGKTLIAEIAIANKLLE-EGGKAVYIVPLKALAEEKFREFKDW-----ERL 94
N+ V PT SGKT+ AE+A L K VYI P+KAL +E+ KDW E +
Sbjct: 1152 NIFVGAPTGSGKTMAAELATWRALHNYPKSKVVYIAPMKALVKERV---KDWGHRLVEPM 1208
Query: 95 GLKVAMATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSS--WIRDVKMLVIDEIHLIGS 152
G+ + TGD + + + +III T EK+D + R S +++DV ++++DEIHL+GS
Sbjct: 1209 GISMIELTGDTNPDVKAVTNANIIITTPEKWDGITRSWKSRKYVQDVSLIILDEIHLLGS 1268
Query: 153 RDRGATLEFIITQML-------GRAQIIGLSATIGNPEELAEWLNAK----LIRSDWRPV 201
DRG LE I+++M + +++GLS + N +LA WLN + R RPV
Sbjct: 1269 -DRGPVLEMIVSRMNYVASQTNKKVRVLGLSTAVANANDLANWLNIRDGLFNFRHSVRPV 1327
Query: 202 KLRKGVFYQGFVFWEDGGSERYNSWEELVYDAVKKG---KGALVFVNMRRKAEKTALELA 258
L ++ GF R S + + A+K + L+FV+ RR+ TA +L
Sbjct: 1328 PLE--IYIDGFP--GRAYCPRMMSMNKPAFQAIKTHSPTQPVLIFVSSRRQTRLTAKDLI 1383
Query: 259 K--------KVKNYLDRKELRELRELAESLEENPTNEKLAKALLSGVAFHHAGLGRDERV 310
+ Y+D +EL E + ++ L AL G+A HHAGL ++R
Sbjct: 1384 AFCGLEDNPRRFLYMDEEEL-------EMIVSEVEDKSLKLALPFGIALHHAGLTENDRK 1436
Query: 311 LVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWRYSE--FGMERIPVLEVQQMMGR 368
+ E+ F +++++AT TL+ G+NTPA VI++ T Y G + + + +V QM+GR
Sbjct: 1437 ISEELFVNNKVQILIATSTLAWGVNTPAHLVIVKGTEYYDAKIGGYKDMDLTDVLQMLGR 1496
Query: 369 AGRPRYDEVGEAIIVSTTEEPSLVIDHYIKGKPEKLFSQLSNESILRSQILALIATFGYS 428
AGRP++D G A I + S G P + + +L + + A IAT
Sbjct: 1497 AGRPQFDNSGVARIFVQDIKKSFYKHFLHSGFPVESYL----HKVLDNHLNAEIATGTID 1552
Query: 429 EFKEIYDFLERTFY 442
+ DFL T++
Sbjct: 1553 CIQGAMDFLTCTYF 1566
Score = 140 bits (349), Expect = 6e-32
Identities = 120/409 (29%), Positives = 199/409 (48%), Gaps = 67/409 (16%)
Query: 40 ENLLVAIPTASGKTLIAEIAIAN---------KLLEEGG---------KAVYIVPLKALA 81
EN+L+ PT +GKT +A +A+ L++E K VYI P+KALA
Sbjct: 294 ENMLICAPTGAGKTDVALLAMLQTISNYVESMNLMDESEPLDVHRDDFKIVYIAPMKALA 353
Query: 82 EEKFREF-KDWERLGLKVAMATGDYDSKDEWLGKYDIIIATAEKFDSLLRHG---SSWIR 137
E + K LGLK TGD + + I++ T EK+D + R +
Sbjct: 354 AEVVEKMGKRLAWLGLKTRELTGDMQLTKTEIAETQILVTTPEKWDVVTRKSVGDTQLAE 413
Query: 138 DVKMLVIDEIHLIGSRDRGATLEFII--TQMLGRA-----QIIGLSATIGNPEELAEWLN 190
V++++IDE+H++ +RGA +E ++ TQ L +I+GLSAT+ N ++A++L
Sbjct: 414 KVRLVIIDEVHMLHD-ERGAVIESLVARTQRLVETSQQMIRIVGLSATLPNYLDVADFLG 472
Query: 191 AKLIRSDWRPVKLRKGVFYQGFVF----------WEDGGSERYNS-WEELVYDAVKK--- 236
V KG+FY F G + NS +E +D V K
Sbjct: 473 ----------VNRYKGLFYFSSAFRPCPIEQHFIGAKGSPKIVNSNIDEACFDKVLKLIQ 522
Query: 237 -GKGALVFVNMRRKAEKTALELAKKV-----KNYLDRKELRELRELAESLEENPTNEKLA 290
G ++FV+ R++ +A +L ++ + LD + E LA+ N++L
Sbjct: 523 EGHQVMIFVHSRKETINSAKKLREQFFHEGEADLLDNSQ-HEKYSLAQRDVSKSKNKELK 581
Query: 291 KALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWRYS 350
+ + H+AG+ R +R L E F G++K++ T TL+ G+N PA+ V+I+ T Y
Sbjct: 582 ELFKYSMGIHNAGMLRSDRHLTERLFSMGILKILCCTATLAWGVNLPAYAVLIKGTQLYD 641
Query: 351 --EFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYI 397
+ + VL+V Q+ GRAGRP+++ A I++T ++ + HYI
Sbjct: 642 PQKGSFVDLGVLDVLQIFGRAGRPQFESSAVAYIITTHDK----LSHYI 686
>pir||S61610 HFM1 protein - yeast (Saccharomyces cerevisiae)
>gi|1150588|emb|CAA64136.1| (X94357) ORF NRE1041;
EMBL:SC22156;U22156 [Saccharomyces cerevisiae]
>gi|1322927|emb|CAA96971.1| (Z72773) ORF YGL251c
[Saccharomyces cerevisiae]
Length = 1046
Score = 176 bits (443), Expect = 5e-43
Identities = 151/479 (31%), Positives = 238/479 (49%), Gaps = 46/479 (9%)
Query: 28 QAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLEEGG-----KAVYIVPLKALAE 82
Q+EA S EN +++ PT SGKT++ E+AI + E K +YI P K+L
Sbjct: 2 QSEAFPSIYESNENCIISSPTGSGKTVLFELAILRLIKETNSDTNNTKIIYIAPTKSLCY 61
Query: 83 EKFREFKDW--ERLGLKVAMATGDYDSKD-EWLGKYDIIIATAEKFDSLLRHGSSWIRD- 138
E + K+W + L V M T D + E K +III T EK+D L R S + R
Sbjct: 62 EMY---KNWFPSFVNLSVGMLTSDTSFLETEKAKKCNIIITTPEKWDLLTRRWSDYSRLF 118
Query: 139 --VKMLVIDEIHLIGSRDRGATLEFIITQMLGRAQ---IIGLSATIGNPEELAEWLN--- 190
VK++++DEIH I + RGA+LE I+T+M Q + LSAT+ N E+LA WL
Sbjct: 119 ELVKLVLVDEIHTIKEK-RGASLEVILTRMNTMCQNIRFVALSATVPNIEDLALWLKTNN 177
Query: 191 ---AKLIRSD--WRPVKLRKGVFYQGFVFWEDGGSER-YNSWEELVYDAVKKGKGALVFV 244
A ++ D +R V+L K V+ F D + YNS + + + L+F
Sbjct: 178 ELPANILSFDESYRQVQLTKFVYGYSFNCKNDFQKDAIYNSKLIEIIEKHADNRPVLIFC 237
Query: 245 NMRRKAEKTALELAKKVKNYLDRKELRELRELAESLEENPTNEKLAKALLSGVAFHHAGL 304
R TA L + N++ K + NP+++ L + + G+AFHHAG+
Sbjct: 238 PTRASTISTAKFL---LNNHIFSKSKKRCNH-------NPSDKILNECMQQGIAFHHAGI 287
Query: 305 GRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWRYSEFGMERIPVLEVQQ 364
++R VE F G I ++ +T TL+ G+N PA+ VII+ T ++ ++ L+V Q
Sbjct: 288 SLEDRTAVEKEFLAGSINILCSTSTLAVGVNLPAYLVIIKGTKSWNSSEIQEYSDLDVLQ 347
Query: 365 MMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKGKPEKLFSQLSNESILRSQILALIAT 424
M+GRAGRP+++ G A+I+ T + ++ I G + L S L I + A +
Sbjct: 348 MIGRAGRPQFETHGCAVIM-TDSKMKQTYENLIHG-TDVLESSLHLNLI--EHLAAETSL 403
Query: 425 FGYSEFKEIYDFLERT-FYAHQGKDPYMLEEKIRRIIYFLLE----NEFIEVTLEDEIK 478
+ ++L T FY GK+P +E R + + +E N+F + L+ +K
Sbjct: 404 ETVYSIETAVNWLRNTFFYVRFGKNPAAYQEVNRYVSFHSVEDSQINQFCQYLLDTLVK 462
>emb|CAA94089.1| (Z70200) U5 snRNP-specific 200kD protein [Homo sapiens]
Length = 1701
Score = 176 bits (443), Expect = 5e-43
Identities = 163/570 (28%), Positives = 264/570 (45%), Gaps = 60/570 (10%)
Query: 16 LRERGIEELY--------PPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLEE 67
LR E LY P Q + + +N+ V PT SGKT+ AE AI LL+
Sbjct: 877 LRNSAFESLYQDKFPFFNPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQN 936
Query: 68 G-GKAVYIVPLKALAEEKFREF--KDWERLGLKVAMATGDYDSKDEWLGKYDIIIATAEK 124
G+ VYI P++ E+ + ++ K +RL KV + TG+ + + LGK +III+T EK
Sbjct: 937 SEGRCVYITPMRLWQEQVYMDWYEKFQDRLNKKVVLLTGETSTDLKLLGKGNIIISTPEK 996
Query: 125 FDSLLRHGSSW--IRDVKMLVIDEIHLIGSRDRGATLE-------FIITQMLGRAQIIGL 175
+D L R ++++ + V+DE+HLIG + G LE +I +Q+ +I+ L
Sbjct: 997 WDILSRRWKQRKNVQNINLFVVDEVHLIGG-ENGPVLEVICSRMRYISSQIERPIRIVAL 1055
Query: 176 SATIGNPEELAEWLNAKLIRS-----DWRPVKLRKGVFYQGFVFWEDGGSERYNSWEELV 230
S+++ N +++A WL + + RPV L + QGF R S + V
Sbjct: 1056 SSSLSNAKDVAHWLGCSATSTFNFHPNVRPVPLELHI--QGFNISHT--QTRLLSMAKPV 1111
Query: 231 YDAVKKG---KGALVFVNMRRKAEKTALELAKKVKNYLDRKELRELRE--LAESLEENPT 285
+ A+ K K +VFV R++ TA+++ + R+ E L LE+ +
Sbjct: 1112 FHAITKHSPKKPVIVFVPSRKQTRLTAIDILTTCAADIQRQRFLHCTEKDLIPYLEKL-S 1170
Query: 286 NEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRD 345
+ L + LL+GV + H GL ER LVE F G I+VVVA+ +L G+N A VII D
Sbjct: 1171 DSTLKETLLNGVGYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMD 1230
Query: 346 TWRYSE--FGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKGKPEK 403
T Y+ P+ +V QM+G A RP D+ G +I+ + D + K E
Sbjct: 1231 TLYYNGKIHAYVDYPIYDVLQMVGHANRPLQDDEGRCVIMCQGSKK----DFFKKFLYEP 1286
Query: 404 LFSQLSNESILRSQILALIATFGYSEFKEIYDFLERTF-YAHQGKDPYM----------- 451
L + + + A I T ++ D+L TF Y ++P
Sbjct: 1287 LPVESHLDHCMHDHFNAEIVTKTIENKQDAVDYLTWTFLYRRMTQNPNYYNLQGISHRHL 1346
Query: 452 ---LEEKIRRIIYFLLENEFIEVTLEDEIKPLPLGVRTTKLYIDPMTAKIFKDTLPRIEK 508
L E + + + L +++ I + E ++ PL LG+ YI+ T ++F +L
Sbjct: 1347 SDHLSELVEQTLSDLEQSKCISIEDEMDVAPLNLGMIAAYYYINYTTIELFSMSL---NA 1403
Query: 509 NPNPLGIFHMISLAPDLTPLSYSKRETSML 538
G+ +IS A + + E ++L
Sbjct: 1404 KTKVRGLIEIISNAAEYENIPIRHHEDNLL 1433
Score = 169 bits (425), Expect = 7e-41
Identities = 132/404 (32%), Positives = 211/404 (51%), Gaps = 40/404 (9%)
Query: 20 GIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLE----------EGG 69
G + L Q++ + + ENLL+ PT +GKT +A + + ++ + +
Sbjct: 42 GFKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDF 101
Query: 70 KAVYIVPLKALAEEKFREF-KDWERLGLKVAMATGDYDSKDEWLGKYDIIIATAEKFDSL 128
K +YI P+++L +E F K G+ VA TGD+ E + II+ T EK+D +
Sbjct: 102 KIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDII 161
Query: 129 LRHGS--SWIRDVKMLVIDEIHLIGSRDRGATLEFIITQMLGRAQ-------IIGLSATI 179
R G ++ + V+++V+DEIHL+ DRG LE ++ + + + +IGLSAT+
Sbjct: 162 TRKGGERTYTQLVRLIVLDEIHLLHD-DRGPVLEALVARAIRNIEMTQEDVRLIGLSATL 220
Query: 180 GNPEELAEWLNAKLIR------SDWRPVKLRKGVFYQGFVFWEDGGSERYNSWEELVYDA 233
N E++A +L + + +RPV L + Y G E +R+ E+VY+
Sbjct: 221 PNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQT--YVGIT--EKKAIKRFQIMNEIVYEK 276
Query: 234 VKKGKG---ALVFVNMRRKAEKTALELA----KKVKNYLDRKELRELRELAESLEENPTN 286
+ + G LVFV+ R++ KTA + +K L +E E+ + E N
Sbjct: 277 IMEHAGKNQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKN 336
Query: 287 EKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDT 346
+L L G A HHAG+ R +R LVED F I+V+V+T TL+ G+N PA VII+ T
Sbjct: 337 LELKDLLPYGFAIHHAGMTRVDRTLVEDLFGDKHIQVLVSTATLAWGVNLPAHTVIIKGT 396
Query: 347 WRYS-EFG-MERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEE 388
YS E G + L++ QM+GRAGRP+YD GE I++++ E
Sbjct: 397 QVYSPEKGRWTELGALDILQMLGRAGRPQYDTKGEGILITSHGE 440
>gi|9755332 C4 zinc finger DNA-binding protein of low sequence specificity in
vitro; Probable 119 kD DNA/RNA helicase family member;
Hfm1p [Saccharomyces cerevisiae]
Length = 1187
Score = 176 bits (443), Expect = 5e-43
Identities = 151/479 (31%), Positives = 238/479 (49%), Gaps = 46/479 (9%)
Query: 28 QAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLEEGG-----KAVYIVPLKALAE 82
Q+EA S EN +++ PT SGKT++ E+AI + E K +YI P K+L
Sbjct: 143 QSEAFPSIYESNENCIISSPTGSGKTVLFELAILRLIKETNSDTNNTKIIYIAPTKSLCY 202
Query: 83 EKFREFKDW--ERLGLKVAMATGDYDSKD-EWLGKYDIIIATAEKFDSLLRHGSSWIRD- 138
E + K+W + L V M T D + E K +III T EK+D L R S + R
Sbjct: 203 EMY---KNWFPSFVNLSVGMLTSDTSFLETEKAKKCNIIITTPEKWDLLTRRWSDYSRLF 259
Query: 139 --VKMLVIDEIHLIGSRDRGATLEFIITQMLGRAQ---IIGLSATIGNPEELAEWLN--- 190
VK++++DEIH I + RGA+LE I+T+M Q + LSAT+ N E+LA WL
Sbjct: 260 ELVKLVLVDEIHTIKEK-RGASLEVILTRMNTMCQNIRFVALSATVPNIEDLALWLKTNN 318
Query: 191 ---AKLIRSD--WRPVKLRKGVFYQGFVFWEDGGSER-YNSWEELVYDAVKKGKGALVFV 244
A ++ D +R V+L K V+ F D + YNS + + + L+F
Sbjct: 319 ELPANILSFDESYRQVQLTKFVYGYSFNCKNDFQKDAIYNSKLIEIIEKHADNRPVLIFC 378
Query: 245 NMRRKAEKTALELAKKVKNYLDRKELRELRELAESLEENPTNEKLAKALLSGVAFHHAGL 304
R TA L + N++ K + NP+++ L + + G+AFHHAG+
Sbjct: 379 PTRASTISTAKFL---LNNHIFSKSKKRCNH-------NPSDKILNECMQQGIAFHHAGI 428
Query: 305 GRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWRYSEFGMERIPVLEVQQ 364
++R VE F G I ++ +T TL+ G+N PA+ VII+ T ++ ++ L+V Q
Sbjct: 429 SLEDRTAVEKEFLAGSINILCSTSTLAVGVNLPAYLVIIKGTKSWNSSEIQEYSDLDVLQ 488
Query: 365 MMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKGKPEKLFSQLSNESILRSQILALIAT 424
M+GRAGRP+++ G A+I+ T + ++ I G + L S L I + A +
Sbjct: 489 MIGRAGRPQFETHGCAVIM-TDSKMKQTYENLIHG-TDVLESSLHLNLI--EHLAAETSL 544
Query: 425 FGYSEFKEIYDFLERT-FYAHQGKDPYMLEEKIRRIIYFLLE----NEFIEVTLEDEIK 478
+ ++L T FY GK+P +E R + + +E N+F + L+ +K
Sbjct: 545 ETVYSIETAVNWLRNTFFYVRFGKNPAAYQEVNRYVSFHSVEDSQINQFCQYLLDTLVK 603
>pir||T00936 ATP-dependent RNA helicase homolog T24P15.18 - Arabidopsis thaliana
>gi|2673917|gb|AAB88651.1| (AC002561) putative U5 small
nuclear ribonucleoprotein-specific protein [Arabidopsis
thaliana]
Length = 2172
Score = 176 bits (441), Expect = 9e-43
Identities = 149/471 (31%), Positives = 243/471 (50%), Gaps = 53/471 (11%)
Query: 19 RGIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKL---LEEGG------ 69
RG+++L Q++ + + + +N+L+ PT +GKT +A + I ++L + GG
Sbjct: 501 RGMQQLNRVQSKVYGTALFKADNILLCAPTGAGKTNVAVLTILHQLGLNMNPGGTFNHGN 560
Query: 70 -KAVYIVPLKALAEEKF----REFKDWERLGLKVAMATGDYDSKDEWLGKYDIIIATAEK 124
K VY+ P+KAL E + KD+ G+ V +GD + + + II+ T EK
Sbjct: 561 YKIVYVAPMKALVAEVVDSLSQRLKDF---GVTVKELSGDQSLTGQEIKETQIIVTTPEK 617
Query: 125 FDSLLRHGS--SWIRDVKMLVIDEIHLIGSRDRGATLEFIITQMLGRAQ-------IIGL 175
+D + R ++ + V++L+IDEIHL+ +RG LE I+ + L + + ++GL
Sbjct: 618 WDIITRKSGDRTYTQLVRLLIIDEIHLLDD-NRGPVLESIVARTLRQIESTKEHIRLVGL 676
Query: 176 SATIGNPEELAEWLNAKLIRS------DWRPVKLRKGVFYQGFVFWEDGGSERYNSWEEL 229
SAT+ N +++A +L L +RPV L G Y G + R+ ++
Sbjct: 677 SATLPNCDDVASFLRVDLKNGLFIFDRSYRPVPL--GQQYIGINVKKP--LRRFQLMNDI 732
Query: 230 VYDAVKKGKG---ALVFVNMRRKAEKTALEL--AKKVKNYLDR--KELRELRELAESLEE 282
Y V G L+FV+ R++ KTA + + L R KE + RE+ + L
Sbjct: 733 CYQKVVAVAGKHQVLIFVHSRKETAKTARAIRDTAMANDTLSRFLKEDSQSREILKCLAG 792
Query: 283 NPTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVI 342
N L + L G A HHAGL R +R +VE+ FR G ++V+++T TL+ G+N PA VI
Sbjct: 793 LLKNNDLKELLPYGFAIHHAGLTRTDREIVENQFRWGNLQVLISTATLAWGVNLPAHTVI 852
Query: 343 IRDTWRYS-EFG--MERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKG 399
I+ T Y+ E G ME P L+V QM+GRAGRP+YD+ GE II++ + + +Y++
Sbjct: 853 IKGTQVYNPERGEWMELSP-LDVMQMIGRAGRPQYDQQGEGIIITGYSK----LQYYLRL 907
Query: 400 KPEKLFSQLSNESILRSQILALIATFGYSEFKEIYDFLERTF-YAHQGKDP 449
E+L + S L Q+ A I +E +L T+ Y ++P
Sbjct: 908 MNEQLPIESQFISKLADQLNAEIVLGTIQNAREACHWLGYTYLYVRMVRNP 958
Score = 161 bits (402), Expect = 3e-38
Identities = 172/613 (28%), Positives = 269/613 (43%), Gaps = 79/613 (12%)
Query: 16 LRERGIEELY-------PPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLE-- 66
LR E LY P Q + T +N++VA PT SGKT+ AE AI LE
Sbjct: 1337 LRNPSYETLYQDFKHFNPVQTQVFTVLYNTSDNVVVAAPTGSGKTICAEFAILRNHLEGP 1396
Query: 67 -EGGKAVYIVPLKALAEEKFREFKDWER-----LGLKVAMATGDYDSKDEWLGKYDIIIA 120
+ VYI PL+A+A+E+FR DWE+ LGL+V TG+ + L K III+
Sbjct: 1397 DSAMRVVYIAPLEAIAKEQFR---DWEKKFGKGLGLRVVELTGETLLDLKLLEKGQIIIS 1453
Query: 121 TAEKFDSLLRHGS--SWIRDVKMLVIDEIHLIGSRDRGATLEFIITQML-------GRAQ 171
T EK+D+L R +I+ V + ++DE+HLIG + G LE I+++M + +
Sbjct: 1454 TPEKWDALSRRWKQRKYIQQVSLFIVDELHLIGGQG-GQVLEVIVSRMRYISSQVGNKIR 1512
Query: 172 IIGLSATIGNPEELAEWLNAKL-----IRSDWRPVKLRKGVFYQGFVFWEDGGSERYNSW 226
I+ LS ++ N ++L EW+ A + RPV L + + +E R +
Sbjct: 1513 IVALSTSLANAKDLGEWIGASSCGVFNFPPNVRPVPLEIHIHGVDILSFE----ARMQAM 1568
Query: 227 EELVYDAV----KKGKGALVFVNMRRKAEKTALELAKKVKNYLDRKE-----LRELRELA 277
+ Y A+ K K A+VFV R+ TA++L +++D + L L EL
Sbjct: 1569 TKPTYTAIVQHAKNKKPAIVFVPTRKHVRLTAVDLI--AYSHMDNMKSPDFLLGNLEELE 1626
Query: 278 ESLEENPTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTP 337
L + E L + L G+ + H GL ++ +V F G I+V V + +L G
Sbjct: 1627 PFLIQ-ICEETLKETLRHGIGYLHEGLSNLDQEIVTQLFEAGRIQVCVMSSSLCWGTPLK 1685
Query: 338 AFRVIIRDTWRYS--EFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDH 395
A V++ T Y E P+ + QMMGR RP D+ G+ +I ++
Sbjct: 1686 AHLVVVMGTHFYDGRENSHSDYPISNLLQMMGRGSRPLLDDAGKCVIFCHAPRK----EY 1741
Query: 396 YIKGKPEKLFSQLSNESILRSQILALIATFGYSEFKEIYDFLERTF-YAHQGKDPYM--- 451
Y K E L + + L A + ++ D+L +F Y ++P
Sbjct: 1742 YKKFLYEALPVESHLQHFLHDNFNAEVVARVIENKQDAVDYLTWSFMYRRLPQNPNYYNL 1801
Query: 452 -----------LEEKIRRIIYFLLENEFIEVTLEDEIKPLPLGVRTTKLYIDPMTAKIFK 500
L E + + L ++ IE+ E ++ PL LG+ + YI+ T + F
Sbjct: 1802 LGVSHRHLSDHLSELVENTLSDLEVSKCIEIDNELDLSPLNLGMIASYYYINYTTIERFS 1861
Query: 501 DTLPRIEKNPNPLGIFHMISLAPDLTPLSYSKRETSMLEDEYYSLMDRLYFELDYENERK 560
L K L I S DL P+ + ED L++ F ++N R
Sbjct: 1862 SLLASKTKMKGLLEILTSAS-EYDLIPIRPGE------EDAVRRLINHQRF--SFQNPRC 1912
Query: 561 FFRAFKTALVLNA 573
KT+ +L A
Sbjct: 1913 TDPRVKTSALLQA 1925
>gb|AAD30595.1|AC007369_5 (AC007369) Putative RNA helicase [Arabidopsis thaliana]
Length = 2171
Score = 175 bits (439), Expect = 2e-42
Identities = 150/471 (31%), Positives = 237/471 (49%), Gaps = 53/471 (11%)
Query: 19 RGIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLEEGG--------- 69
+G+++L Q++ + + + EN+L+ PT +GKT +A + I +L
Sbjct: 500 KGMQQLNRVQSKVYDTALFKAENILLCAPTGAGKTNVAMLTILQQLEMNRNTDGTYNHGD 559
Query: 70 -KAVYIVPLKALAEEKF----REFKDWERLGLKVAMATGDYDSKDEWLGKYDIIIATAEK 124
K VY+ P+KAL E KD+ G+ V +GD + + II+ T EK
Sbjct: 560 YKIVYVAPMKALVAEVVGNLSNRLKDY---GVIVRELSGDQSLTGREIEETQIIVTTPEK 616
Query: 125 FDSLLRHGS--SWIRDVKMLVIDEIHLIGSRDRGATLEFIITQMLGRAQ-------IIGL 175
+D + R ++ + V++L+IDEIHL+ +RG LE I+ + L + + ++GL
Sbjct: 617 WDIITRKSGDRTYTQLVRLLIIDEIHLLHD-NRGPVLESIVARTLRQIETTKENIRLVGL 675
Query: 176 SATIGNPEELAEWLNAKLIRS------DWRPVKLRKGVFYQGFVFWEDGGSERYNSWEEL 229
SAT+ N E++A +L L + +RPV L + Y G + +R+ +L
Sbjct: 676 SATLPNYEDVALFLRVDLKKGLFKFDRSYRPVPLHQQ--YIGISVKKP--LQRFQLMNDL 731
Query: 230 VYDAVKKGKG---ALVFVNMRRKAEKTALEL--AKKVKNYLDR--KELRELRELAESLEE 282
Y V G G L+FV+ R++ KTA + + L R KE R++ S E+
Sbjct: 732 CYQKVLAGAGKHQVLIFVHSRKETSKTARAIRDTAMANDTLSRFLKEDSVTRDVLHSHED 791
Query: 283 NPTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVI 342
N L L G A HHAGL R +R +VE F +G ++V+V+T TL+ G+N PA VI
Sbjct: 792 IVKNSDLKDILPYGFAIHHAGLSRGDREIVETLFSQGHVQVLVSTATLAWGVNLPAHTVI 851
Query: 343 IRDTWRYS-EFG--MERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKG 399
I+ T Y+ E G ME P L+V QM+GRAGRP+YD+ GE II++ E + +Y+
Sbjct: 852 IKGTQVYNPEKGAWMELSP-LDVMQMLGRAGRPQYDQHGEGIIITGYSE----LQYYLSL 906
Query: 400 KPEKLFSQLSNESILRSQILALIATFGYSEFKEIYDFLERTF-YAHQGKDP 449
E+L + S L Q+ A I +E +L T+ Y ++P
Sbjct: 907 MNEQLPIESQFISKLADQLNAEIVLGTVQNAREACHWLGYTYLYIRMVRNP 957
Score = 163 bits (408), Expect = 7e-39
Identities = 166/575 (28%), Positives = 253/575 (43%), Gaps = 71/575 (12%)
Query: 16 LRERGIEELY-------PPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLEEG 68
LR E LY P Q + T +N+LVA PT SGKT+ AE AI E
Sbjct: 1336 LRNPNYEILYQDFKHFNPVQTQVFTVLYNTNDNVLVAAPTGSGKTICAEFAILRNHHEGP 1395
Query: 69 G---KAVYIVPLKALAEEKFR--EFKDWERLGLKVAMATGDYDSKDEWLGKYDIIIATAE 123
+ VYI PL+A+A+E+FR E K + LGL+V TG+ + L K III+T E
Sbjct: 1396 DATMRVVYIAPLEAIAKEQFRIWEGKFGKGLGLRVVELTGETALDLKLLEKGQIIISTPE 1455
Query: 124 KFDSLLRHGS--SWIRDVKMLVIDEIHLIGSRDRGATLEFII-------TQMLGRAQIIG 174
K+D+L R +++ V + ++DE+HLIG + G LE I+ +Q++ + +I+
Sbjct: 1456 KWDALSRRWKQRKYVQQVSLFIVDELHLIGGQ-HGPVLEVIVSRMRYISSQVINKIRIVA 1514
Query: 175 LSATIGNPEELAEWLNAKL-----IRSDWRPVKLR---KGVFYQGFVFWEDGGSERYNSW 226
LS ++ N ++L EW+ A RPV L +GV F R +
Sbjct: 1515 LSTSLANAKDLGEWIGASSHGLFNFPPGVRPVPLEIHIQGVDISSF-------EARMQAM 1567
Query: 227 EELVYDAV----KKGKGALVFVNMRRKAEKTALELAKKVKNYLDRKE-----LRELRELA 277
+ Y A+ K K A+VFV R+ TA++L +++D + L +L EL
Sbjct: 1568 TKPTYTAIVQHAKNKKPAIVFVPTRKHVRLTAVDL--MAYSHMDNPQSPDFLLGKLEEL- 1624
Query: 278 ESLEENPTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTP 337
+ E E L + L G+ + H GL ++ +V F G I+V V + +L G
Sbjct: 1625 DPFVEQIREETLKETLCHGIGYLHEGLSSLDQEIVTQLFEAGRIQVCVMSSSLCWGTPLT 1684
Query: 338 AFRVIIRDTWRYS--EFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDH 395
A V++ T Y E PV ++ QMMGRA RP D G+ +I ++
Sbjct: 1685 AHLVVVMGTQYYDGRENSHSDYPVPDLLQMMGRASRPLLDNAGKCVIFCHAPRK----EY 1740
Query: 396 YIKGKPEKLFSQLSNESILRSQILALIATFGYSEFKEIYDFLERTF-YAHQGKDPYM--- 451
Y K E + + L A + ++ D+L TF Y ++P
Sbjct: 1741 YKKFLYEAFPVESQLQHFLHDNFNAEVVAGVIENKQDAVDYLTWTFMYRRLPQNPNYYNL 1800
Query: 452 -----------LEEKIRRIIYFLLENEFIEVTLEDEIKPLPLGVRTTKLYIDPMTAKIFK 500
L E + + L ++ IEV E E+ PL LG+ + YI T + F
Sbjct: 1801 QGVSHRHLSDHLSELVENTLSDLEASKCIEVEDEMELSPLNLGMIASYYYISYTTIERFS 1860
Query: 501 DTLPRIEKNPNPLGIFHMISLAPDLTPLSYSKRET 535
L K L I S D+ P+ + +T
Sbjct: 1861 SLLSSKTKMKGLLEILTSAS-EYDMIPIRPGEEDT 1894
>dbj|BAB14698.1| (AK023840) unnamed protein product [Homo sapiens]
Length = 774
Score = 174 bits (437), Expect = 3e-42
Identities = 132/404 (32%), Positives = 212/404 (51%), Gaps = 40/404 (9%)
Query: 20 GIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLE----------EGG 69
G + L Q++ + + ENLL+ PT +GKT +A + + ++ + +
Sbjct: 152 GFKTLNRIQSKLYRAALETAENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDF 211
Query: 70 KAVYIVPLKALAEEKFREF-KDWERLGLKVAMATGDYDSKDEWLGKYDIIIATAEKFDSL 128
K +YI P+++L +E F K G+ VA TGD+ E + II+ T EK+D +
Sbjct: 212 KIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLSKEEISATQIIVCTPEKWDII 271
Query: 129 LRHGS--SWIRDVKMLVIDEIHLIGSRDRGATLEFIITQMLGRAQ-------IIGLSATI 179
R G ++ + V+++++DEIHL+ DRG LE ++ + + + +IGLSAT+
Sbjct: 272 TRKGGERTYTQLVRLIILDEIHLLHD-DRGPVLEALVARAIRNIEMTQEDVRLIGLSATL 330
Query: 180 GNPEELAEWLNAKLIR------SDWRPVKLRKGVFYQGFVFWEDGGSERYNSWEELVYDA 233
N E++A +L + + +RPV L + Y G E +R+ E+VY+
Sbjct: 331 PNYEDVATFLRVDPAKGLFYFDNSFRPVPLERT--YVGIT--EKKAIKRFQIMNEIVYEK 386
Query: 234 VKKGKG---ALVFVNMRRKAEKTALELA----KKVKNYLDRKELRELRELAESLEENPTN 286
+ + G LVFV+ R++ KTA + +K L +E E+ + E N
Sbjct: 387 IMEHAGKNQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKN 446
Query: 287 EKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDT 346
+L LL G A HHAG+ R +R LVED F I+V+V+T TL+ G+N PA VII+ T
Sbjct: 447 LELKDLLLYGFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGT 506
Query: 347 WRYS-EFG-MERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEE 388
YS E G + L++ QM+GRAGRP+YD GE I++++ E
Sbjct: 507 QVYSPEKGRWTELGALDILQMLGRAGRPQYDTKGEGILITSHGE 550
>pir||T39188 probable U5 snRNP-specific 200kd protein - fission yeast
(Schizosaccharomyces pombe) >gi|6014422|emb|CAB57421.1|
(AL121764) putative U5 snRNP-specific 200kd protein
[Schizosaccharomyces pombe]
Length = 2176
Score = 173 bits (435), Expect = 5e-42
Identities = 129/388 (33%), Positives = 206/388 (52%), Gaps = 48/388 (12%)
Query: 40 ENLLVAIPTASGKTLIAEIAIANKLLE----------EGGKAVYIVPLKALAEEKFREF- 88
EN+L+ PT +GKT +A + I N+L + + K VYI PLKAL +E F
Sbjct: 536 ENILLCAPTGAGKTNVAMLCILNELQKHLREDLSFNLQNFKIVYIAPLKALVQEMVNNFS 595
Query: 89 KDWERLGLKVAMATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGS--SWIRDVKMLVIDE 146
K ++VA TGD + + + II+ T EK+D + R + S++ V++++IDE
Sbjct: 596 KRLTPYNIRVAELTGDSQLTKQQISETQIIVTTPEKWDIITRKANDLSYVNLVRLVIIDE 655
Query: 147 IHLIGSRDRGATLEFIITQM-------LGRAQIIGLSATIGNPEELAEWLNAK------L 193
+HL+ +RG LE I+ ++ L + +++GLSAT+ N ++A +L+
Sbjct: 656 VHLLHD-ERGPVLESIVARIFRHQEETLEQVRLVGLSATLPNYTDVASFLHVDPKKGLFY 714
Query: 194 IRSDWRPVKLRKGVFYQGFV-FWEDGGSERYNSWEELVYDAVKKGKG---ALVFVNMRRK 249
S +RP L+ Q F+ E +R + E Y+ V + G L+FV+ R++
Sbjct: 715 FDSTYRPCPLK-----QEFIGITEKTPFKRMQTTNEACYEKVMQHAGKNQVLIFVHSRKE 769
Query: 250 AEKTALELAKKVKNYLDRKELREL-------RELAESLEENPTNEKLAKALLSGVAFHHA 302
KTA + K L+ + + L RE+ + ++ ++E L L G A HHA
Sbjct: 770 TAKTARFIRDKA---LEEETIGHLLRSDAASREILRAEADSTSDENLKDLLPYGFAIHHA 826
Query: 303 GLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWRYS-EFGM-ERIPVL 360
G+ R++R ED F G I+V+V+T TL+ G+N PA VII+ T YS E G+ +
Sbjct: 827 GMRREDRQTSEDLFADGTIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGIWTELSPQ 886
Query: 361 EVQQMMGRAGRPRYDEVGEAIIVSTTEE 388
+V QM+GRAGRP++D GE II++ E
Sbjct: 887 DVLQMLGRAGRPQFDTYGEGIIITAHSE 914
>gb|AAF49564.2| (AE003529) CG5931 gene product [Drosophila melanogaster]
Length = 2149
Score = 171 bits (428), Expect = 3e-41
Identities = 199/768 (25%), Positives = 356/768 (45%), Gaps = 92/768 (11%)
Query: 5 ELNVSEKIKEILRE--RGIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIAN 62
EL +K+ + ++ G + L Q+ + + EN+L+ PT +GKT +A + +
Sbjct: 479 ELQPVDKLPKYVQPVFEGFKTLNRIQSRLYKAALDSDENMLLCAPTGAGKTNVALLTMMR 538
Query: 63 KL---LEEGG-------KAVYIVPLKALAEEKFREF-KDWERLGLKVAMATGDYDSKDEW 111
++ + E G K +Y+ P+K+L +E F + L V+ TGD+ E
Sbjct: 539 EIGKHINEDGTINAQDFKIIYVAPMKSLVQEMVGNFGRRLACYNLTVSELTGDHQLTREQ 598
Query: 112 LGKYDIIIATAEKFDSLLRHGS--SWIRDVKMLVIDEIHLIGSRDRGATLEFIITQMLGR 169
+ +I+ T EK+D + R G +++ V++++IDEIHL+ +RG LE ++ + +
Sbjct: 599 IAATQVIVCTPEKWDIITRKGGERTFVSLVRLVIIDEIHLLHD-ERGPVLEALVARTIRN 657
Query: 170 AQ-------IIGLSATIGNPEELAEWLNAK------LIRSDWRPVKLRKGVFYQGFVFWE 216
+ ++GLSAT+ N +++A +L K + +RPV L + Y G E
Sbjct: 658 IETTQEEVRLVGLSATLPNYQDVATFLRVKPDKGLFYFDNSYRPVSLEQQ--YIGVT--E 713
Query: 217 DGGSERYNSWEELVYDAVKKGKG---ALVFVNMRRKAEKTALELAKKVKNYLDRKELRE- 272
+R+ E+VY+ + G LVFV+ R++ KTA + L++ L
Sbjct: 714 KKALKRFQVMNEIVYEKTMEHAGRNQVLVFVHSRKETGKTARAVRDMC---LEQDTLGSF 770
Query: 273 LRELAESLE------ENPTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVA 326
L+E + S+E E N +L + L G A HHAG+ R +R LVED F I+V+V+
Sbjct: 771 LKEGSASMEVLRTEAEQVKNTELKELLPYGFAIHHAGMTRVDRTLVEDLFADRHIQVLVS 830
Query: 327 TPTLSAGINTPAFRVIIRDTWRYS-EFG-MERIPVLEVQQMMGRAGRPRYDEVGEAIIVS 384
T TL+ G+N PA VII+ T Y+ E G + L+V QM+GRAGRP+YD GE I+++
Sbjct: 831 TATLAWGVNLPAHTVIIKGTQVYNPEKGRWVELSALDVLQMLGRAGRPQYDTKGEGILIT 890
Query: 385 TTEEPSLVIDHYIKGKP------EKLFSQLSNESILRS--QILALIATFGYSEFKEIYDF 436
E + + P KL L+ E +L + + + GY+ + I
Sbjct: 891 NHSELQFYLSLLNQQLPIESQFISKLPDMLNAEIVLGTVQHLQDAVNWLGYT-YLYIRML 949
Query: 437 LERTFY--AHQG--KDPYMLEEK---IRRIIYFLLENEFIEVTLE-DEIKPLPLGVRTTK 488
T Y +H DP + + + + L + I+ + + LG +
Sbjct: 950 RNPTLYGVSHDAIKADPLLEQHRADLLHTAACCLERSGLIKYDRKTGHFQVTDLGRIASH 1009
Query: 489 LYIDPMTA----KIFKDTLPRIEKNPNPLGIFHMISLAPDLTPLSYSKRETSMLEDEYYS 544
Y+ T ++ K TL IE +F + SL+ + +S + E L+
Sbjct: 1010 YYLTHETMLTYNQLLKQTLSEIE-------LFRVFSLSSEFRHISVREEEKLELQ----K 1058
Query: 545 LMDRLYFELDYENERKFFRAFKTALVLNAWINEVPEGEIVERFNVEPGDIYRIVETAEWL 604
LM+R+ + E + K ++L A+I+++ +E F + D+ I ++A L
Sbjct: 1059 LMERVPIPIKESIEE---HSAKVNVLLQAYISQLK----LEGFAL-MSDMVFITQSAARL 1110
Query: 605 IYSLGEIAKVLEASQEVVDYVNTLRLRVKHGIREELIPLMELPMVGRKRARALYNAGFK- 663
+ ++ EI + ++ D TL + + + + PL + + + A+ L F
Sbjct: 1111 MRAIFEIV-LTRGWAQLADKTLTLCKMIDRRMWQSMTPLRQFKKMPDEIAKKLEKKHFPW 1169
Query: 664 -DLESIRNAKPSELLRIEGIGAKIVEGIFKYLGKEVKITERP-RKGTL 709
L + + EL+R+ +G I + + ++ E+ +P +GTL
Sbjct: 1170 GRLYDLEPHELGELIRVPKLGKTIHKFVHQFPKLELSTHIQPITRGTL 1217
Score = 148 bits (370), Expect = 2e-34
Identities = 161/623 (25%), Positives = 281/623 (44%), Gaps = 56/623 (8%)
Query: 26 PPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLEEG-GKAVYIVPLKALAEEK 84
P Q + + EN+ V PT SGK IAE AI + + VY+V +ALA+
Sbjct: 1349 PIQTQVFNAVYNSDENVFVGAPTGSGKMTIAEFAIMRLFTTQSDARCVYLVSEEALADLV 1408
Query: 85 FREFKD-WERLGLKVAMATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSSW--IRDVKM 141
F ++ + L +KV TG+ + + + K ++I TA+K+D L R ++ V +
Sbjct: 1409 FADWHSKFGSLDIKVVKLTGETGTDLKLIAKGQLVITTADKWDVLSRRWKQRKNVQLVNL 1468
Query: 142 LVIDEIHLIGSRDRGATLE-------FIITQMLGRAQIIGLSATIGNPEELAEWL----N 190
++DE+ L+G + G LE +I +Q+ + +I+ LSA++ + ++A+WL N
Sbjct: 1469 FIVDELQLVGGEE-GPVLEIVCSRMRYISSQIEKQIRIVALSASLTDARDVAQWLGCNPN 1527
Query: 191 AKL-IRSDWRPVKLRKGVFYQGFVFWEDGGSERYNSWEELVYDAVKK---GKGALVFVNM 246
A RP+ L + QG+ + + R + + VY+A+ K K +VFV+
Sbjct: 1528 ATFNFHPSVRPIPLELHI--QGYNVTHN--ATRIATMSKPVYNAILKYSAHKPVIVFVSS 1583
Query: 247 RRKAEKTALELAKKVKNYLDRKELRELREL-AESLEENPTNEKLAKALLSGVAFHHAGLG 305
R++A TA+++ + L E + E T++ L + L GVA+ H GL
Sbjct: 1584 RKQARLTAIDVLTYAASDLQPNRFFHAEEEDIKPFLERMTDKTLKETLAQGVAYLHEGLS 1643
Query: 306 RDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWRYS--EFGMERIPVLEVQ 363
+ LVE F G ++V V + L G++ A VII DT Y+ E P+ +V
Sbjct: 1644 ASDHRLVEQLFDSGAVQVAVISRDLCWGMSISAHLVIIMDTQFYNGKNHSYEDYPITDVL 1703
Query: 364 QMMGRAGRPRYDEVGEAIIVSTT----------EEPSLVIDHYIKGKPEKLFSQLSNESI 413
QM+GRA RP D + +++ + EP + H + +++ ++I
Sbjct: 1704 QMIGRANRPNEDADAKCVLMCQSSKKDFFKKFINEPLPIESHLDHRMHDHFNAEVVTKTI 1763
Query: 414 LRSQ--ILALIATFGYSEFKEIYDFLERTFYAHQGKDPYMLEEKIRRIIYFLLENEFIEV 471
Q + L TF Y + ++ H+ + L E + + L +++ I V
Sbjct: 1764 ENKQDAVDYLTWTFLYRRLTQNPNYYNLQGVTHRHLSDH-LSELVENTLSDLEQSKCISV 1822
Query: 472 TLEDEIKPLPLGVRTTKLYIDPMTAKIFKDTLPRIEKNPNPLGIFHMISLAPDLTPLSYS 531
+ + PL LG+ YI+ T ++F +L G+ +IS A + +
Sbjct: 1823 EDDMDTLPLNLGMIAAYYYINYTTIELFSLSL---NSKTKVRGLLEIISSAAEYEDVVVR 1879
Query: 532 KRETSMLEDEYYSLMDRLYFELDYENER--KFFRA-FKTALVLNAWINEVPEGEIVERFN 588
E +L +L RL +L NE KF KT L+L A ++ + G ++
Sbjct: 1880 HHEEQVLR----TLSQRLPNKLTGPNETAPKFNDPHIKTNLLLQAHLSRLQLGPELQ--- 1932
Query: 589 VEPGDIYRIVETAEWLIYSLGEI 611
GD +I+ A LI + ++
Sbjct: 1933 ---GDTEQILSKAIRLIQACVDV 1952
>pir||T04456 hypothetical protein F4D11.100 - Arabidopsis thaliana
>gi|3063700|emb|CAA18591.1| (AL022537) putative protein
[Arabidopsis thaliana] >gi|7270174|emb|CAB79987.1|
(AL161581) putative protein [Arabidopsis thaliana]
Length = 1548
Score = 168 bits (421), Expect = 2e-40
Identities = 167/680 (24%), Positives = 299/680 (43%), Gaps = 96/680 (14%)
Query: 117 IIIATAEKFDSLLRH--GSSWIRDVKMLVIDEIHLIGSRDRGATLEFIITQML------- 167
+ + T EK +SL+ + ++ ++VIDE+H++G + RG LE ++T++
Sbjct: 58 VAVCTIEKANSLINRLLEEGRLSELGIIVIDELHMVGDQHRGYLLELMLTKLRYAAGEGS 117
Query: 168 -------------GRA------QIIGLSATIGNPEELAEWLN-----------AKLIRSD 197
G+A QI+G+SAT+ N +A+WL A L +++
Sbjct: 118 SESSSGESSGTSSGKADPAHGLQIVGMSATMPNVGAVADWLQVSKTNHNLCVYAALYQTE 177
Query: 198 WRPVKLRKGVFYQGFVFWE------------DGGSERYNSWEELVYDAVKKGKGALVFVN 245
+RPV L + + ++ + D G + + EL + V++G L+F +
Sbjct: 178 FRPVPLEEYIKVGSTIYNKKMEVVRTIPKAADMGGKDPDHIVELCNEVVQEGNSVLIFCS 237
Query: 246 MRRKAEKTALELAKKVKNYL-----DRKELRELRELAESLEENPT--NEKLAKALLSGVA 298
R+ E TA ++K +KN + E ++R ++L +P+ + L + L SGVA
Sbjct: 238 SRKGCESTARHISKLIKNVPVNVDGENSEFMDIRSAIDALRRSPSGVDPVLEETLPSGVA 297
Query: 299 FHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWRYSEFGMERIP 358
+HHAGL +ER +VE +RKGL++V+ AT TL+AG+N PA RVI R G + I
Sbjct: 298 YHHAGLTVEEREIVETCYRKGLVRVLTATSTLAAGVNLPARRVIFRQPM----IGRDFID 353
Query: 359 VLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKGKPEKLFSQLSNESILRSQI 418
+QM GRAGR D G+++++ E ++ + P +++ + I
Sbjct: 354 GTRYKQMSGRAGRTGIDTKGDSVLICKPGELKRIMALLNETCPPLQSCLSEDKNGMTHAI 413
Query: 419 LALIATFGYSEFKEIYDFLERTFYAHQGKDPYMLEEKIRRIIYFLLENEFIEVTLEDEIK 478
L ++A K+I+ ++ + ++ Y R L E + L+D ++
Sbjct: 414 LEVVAGGIVQTAKDIHRYVRKFLEWNEETKLYTTTPLGRGSFGSSLCPEESLIVLDDLLR 473
Query: 479 PLPLGVRTTKLYIDPMTAKI--------------FKDTLPRIEKNPNPLGIFH--MISLA 522
V + L++ + I F + P + N +G+ ++ +A
Sbjct: 474 AREGLVMASDLHLVYLVTPINVGVEPNWELYYERFMELSPLEQSVGNRVGVVEPFLMRMA 533
Query: 523 PDLTPLSYSKRE--TSMLEDEYYSLMDRLYFE-LDYENERKFFRAFKTALVLNAWINEVP 579
T + ++ + L EY S + L E + + F AL+L+ + E
Sbjct: 534 HGATVRTLNRPQDVKKNLRGEYDSRHGSTSMKMLSDEQMLRVCKRFFVALILSKLVQEAS 593
Query: 580 EGEIVERFNVEPGDIYRIVETAEWLIYSLGEIAKVLEASQEVVDYVNTLRLRVKHGIREE 639
E+ E F V G + + E A + + L ++ V + RV G+R E
Sbjct: 594 VTEVCEAFKVARGMVQALQENAGRFSSMVSVFCERL-GWHDLEGLVAKFQNRVSFGVRAE 652
Query: 640 LIPLMELPMVGRKRARALYNAGFKDLESIRNAKPSELLR---------IEGIGAKIVEGI 690
++ L +P + RARALY AG + ++I A E+++ EG G + +
Sbjct: 653 IVELTSIPYIKGSRARALYKAGLRTSQAIAEASIPEIVKALFESSAWAAEGTGQRRI--- 709
Query: 691 FKYLGKEVKITERPRKGTLD 710
+LG KI RK L+
Sbjct: 710 --HLGLAKKIKNGARKIVLE 727
>pir||C69187 conserved hypothetical protein MTH656 - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2621738|gb|AAB85161.1| (AE000845) ATP-dependent RNA
helicase related protein [Methanobacterium
thermoautotrophicum]
Length = 837
Score = 162 bits (407), Expect = 9e-39
Identities = 132/399 (33%), Positives = 200/399 (50%), Gaps = 63/399 (15%)
Query: 5 ELNVSEKIKEILRERGIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKL 64
+L V EK K +L+ G L P Q A+ +G+LEGE+L+V TASGKTLIAE+A +
Sbjct: 204 KLAVPEKFKRMLKREGNTVLRPVQVLAVDAGLLEGEDLMVVSATASGKTLIAELAGIPRA 263
Query: 65 LEEGGKAVYIVPLKALAEEKFREF-KDWERLGLKVAMATG--DYDSKDEW------LGKY 115
L G K +Y+ PL ALA +K+R+F + + L LK A+ G ++DE + K
Sbjct: 264 L-GGEKFIYLTPLVALANQKYRDFRRRYSPLKLKTAIKVGMSRIRARDELRIPETDVSKA 322
Query: 116 DIIIATAEKFDSLLRHGSSWI-RDVKMLVIDEIHLIGSRDRGATLEFI---ITQMLGRAQ 171
DI++ T E D +LR G S I DV ++VIDEIH + +RG+ L+ + I ++ AQ
Sbjct: 323 DIVVGTYEGMDYILRAGRSGILGDVGVVVIDEIHTLEDEERGSRLKGMIKRIRRLFPDAQ 382
Query: 172 IIGLSATIGNPEELAEWLNAKLIRSDWRPVKLRKGVFYQGFVFWEDGGSERYN-----SW 226
II LSAT+ N E+A +L+ D RPV L + + + G ++ N +
Sbjct: 383 IIALSATVKNNLEVASEFGLRLVEYDRRPVPLERHLVF------SRGEEDKKNLILRLAE 436
Query: 227 EELVYDAVKKGKG-ALVFVNMRRKAEKTALELAKKVKNYLDRKELRELRELAESLEENPT 285
E ++ K +G +VF N RRK + + +YL R+ +R
Sbjct: 437 REFSTESEKGFRGQTIVFTNSRRK--------TRLIADYLTRRGVR-------------- 474
Query: 286 NEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRD 345
A +HAGL ER +E F + +V T L+AG++ PA +V+
Sbjct: 475 -----------AAAYHAGLSYRERQRIERAFASQELAAIVTTAALAAGVDFPASQVVFET 523
Query: 346 TWRYSEFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVS 384
+ + M E QM+GRAGRP Y + G +++
Sbjct: 524 LLMGNRWLMPN----EFAQMLGRAGRPSYHDRGVVYVLA 558
>pir||H70414 conserved hypothetical protein aq_1328 - Aquifex aeolicus
>gi|2983748|gb|AAC07309.1| (AE000734) hypothetical
protein [Aquifex aeolicus]
Length = 764
Score = 153 bits (384), Expect = 4e-36
Identities = 144/455 (31%), Positives = 232/455 (50%), Gaps = 53/455 (11%)
Query: 11 KIKEILRERGIEELYPPQA----EALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLE 66
K +E+++ + ++E P + + L EG N LV+ PT++GK+L A + + K
Sbjct: 31 KTEELIKGKEVDERIPYELLNPIQTLFYKEYEGGNALVSAPTSAGKSLTAFLFLRGK--- 87
Query: 67 EGGKAVYIVPLKALAEEKFREFKDWERLGLKVAMATGDYDSKDEWLGKYDIIIATAEKFD 126
EG K V+ P ++L EK E ++ R KV + TG+ + + K ++++AT E
Sbjct: 88 EGIK-VFTAPTRSLVYEKASELRELFRK--KVEVRTGEVFELYKEI-KSEVVVATYESLA 143
Query: 127 SLLRHGSSWIRDVKMLVIDEIH-LIGSRDRGATLEFIITQML-GRAQIIGLSATIGNPEE 184
LR+ +SWI + + +VIDEIH L+GSR G LE IIT +L G +I+GLSAT+ E+
Sbjct: 144 LALRNRASWIEEARGVVIDEIHQLMGSR--GWILEEIITFLLDGNYEILGLSATLPGAEQ 201
Query: 185 LAEWLNAKL-IRSDWRPVKLRKGVF----YQGFVFWEDGGSERYNSWEEL---VYDAVKK 236
LA+W+ A+L I S WRPV L + + ++ F G ++ +L +Y K
Sbjct: 202 LAKWIKAELFIESRWRPVPLERKIIPLIKFEEFTKLPKGATQDEKIANKLLGALYTLKKP 261
Query: 237 GKGALVFVNMRRKAEKTALELAKKVKNYLDRKELRELRELAESLEENPTNEKLAKALLSG 296
+ ++FV+ ++ LE+A + K + + +E E +E
Sbjct: 262 DEQVILFVH-KKSVGWNVLEIANREKIGIMNETTPFEKEEREEVE--------------- 305
Query: 297 VAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWRYSEFGMER 356
+AFH+A + ++ER +E FR+G + V+VAT TL+ G+N PA VII Y +R
Sbjct: 306 LAFHNADVPKEERDEIEKAFREGKLPVLVATSTLAYGVNLPADTVIISVRSFYDRERRQR 365
Query: 357 ---IPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKGKPEKL---FSQLSN 410
VL++ QM GRAGR E G + I+ + ++ K EKL F
Sbjct: 366 KFFPDVLDILQMEGRAGRLGIKEKGYSYILPYGAKE----ENLAKALSEKLKEEFKPYLR 421
Query: 411 ESIL---RSQILALIATFGY-SEFKEIYDFLERTF 441
E L + ++L+L G+ E + FLERT+
Sbjct: 422 EVFLSEEKLKVLSLFILVGFLYEGENFRKFLERTY 456
>gb|AAG20308.1| (AE005105) DNA repair protein; Rad24a [Halobacterium sp. NRC-1]
Length = 592
Score = 153 bits (383), Expect = 6e-36
Identities = 149/528 (28%), Positives = 241/528 (45%), Gaps = 106/528 (20%)
Query: 3 VGELNVSEKIKEILRERGIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIAN 62
V EL++ ++ + +R EEL P Q+ A+ +G++EG++ +V TA+GKTL+ EIA +
Sbjct: 110 VSELDLHPDVQGLFEDR-FEELLPVQSLAVENGLVEGDDQMVVSATATGKTLVGEIAGLH 168
Query: 63 KLLEEGGKAVYIVPLKALAEEKFREFKDWERLGLKVAMATGDYDSKDE---WLGKYDIII 119
+L GK +++VPL ALA +K +F+D V + G +D+ + DII+
Sbjct: 169 RLQSGNGKLLFLVPLVALANQKHEDFQDEYGHLANVTIRVGSSRIRDDGHAFDPAADIIV 228
Query: 120 ATAEKFDSLLRHGSSWIRDVKMLVIDEIHLIGSRDRGATLEFIITQM------------- 166
T E D LR G + D+ +VIDE+H + DRG L+ +I+++
Sbjct: 229 GTYEGIDHALRTGRD-LGDIGTVVIDEVHTLKEDDRGHRLDGLISRLKYYCEQRREERAG 287
Query: 167 LGRAQIIGLSATIGNPEELAEWLNAKLIRSDWRPVKLRKGVFYQGFVFWEDGGSERYNSW 226
AQ + LSAT+GNP ELA L A L+ + RPV + + V + G+E+ +
Sbjct: 288 YDGAQWVYLSATVGNPGELAGKLRANLVEFEERPVPIERHVTFA-------DGAEKPDIE 340
Query: 227 EELVYDAVKKGKG------ALVFVNMRRKAEKTALELAKKVKNYLDRKELRELRELAESL 280
LV + ++F N RR+ E+++K+ +Y R
Sbjct: 341 NTLVRREFDQESSMGYRGQTIIFTNSRRRCN----EISRKL-DYPSRP------------ 383
Query: 281 EENPTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFR 340
+HAGL ER VE F + VV T L+AG++ PA +
Sbjct: 384 -------------------YHAGLDYGERKSVERQFGDQDLAAVVTTAALAAGVDFPANQ 424
Query: 341 VIIRDTWRYSEFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIV------------STTEE 388
VI DT G+E + V E +QM+GRAGRP Y + G+ ++ T EE
Sbjct: 425 VIF-DT---LAMGIEWLSVQEFEQMLGRAGRPDYHDRGKVYVLVEPDASYHSSMEGTEEE 480
Query: 389 PSLVIDHYIKGKPEKLFSQLSNESILRSQILALIATFGYSEFKEIYDFLERTFYAHQGKD 448
+ + +KG E + + ++ + + + T G + K + D + G
Sbjct: 481 IAFTL---LKGDMENVVTHYDEDAAVEETLANV--TVGGTAAKRLNDRM-------VGDI 528
Query: 449 PYMLEEKIRRIIYFLLENEFIEVTLEDEIKPLPLGVRTTKLYIDPMTA 496
P + + LLE EFI D ++P G T ++DP +A
Sbjct: 529 P------TKHALGKLLEYEFI-----DGLEPTDRGRAVTTHFLDPDSA 565
>pir||T41378 probable helicase - fission yeast (Schizosaccharomyces pombe)
>gi|3136048|emb|CAA19107.1| (AL023592) putative
DEAD/DEAH box helicase [Schizosaccharomyces pombe]
Length = 1213
Score = 143 bits (358), Expect = 5e-33
Identities = 159/549 (28%), Positives = 241/549 (42%), Gaps = 104/549 (18%)
Query: 39 GENLLVAIPTASGKTLIAEIAIANKLLEEGGKAVYIVPLKALAEEKFREFKD-WERLGLK 97
G+++ VA T++GKT++AE AIA + KA+Y P+KAL+ +KFR+FK +E +G+
Sbjct: 295 GDSVFVAAHTSAGKTVVAEYAIA-LAQKHMTKAIYTSPIKALSNQKFRDFKHKFEDVGI- 352
Query: 98 VAMATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSSWIRDVKMLVIDEIHLIGSRDRGA 157
TGD E ++ T E S+L G+ IRDV+ ++ DE+H + +RG
Sbjct: 353 ---LTGDVQVNPEG----SCLLMTTEILRSMLYRGADLIRDVEFVIFDEVHYVNDLERGV 405
Query: 158 TLEFIITQMLGRAQIIGLSATIGNPEELAEWL------NAKLIRSDWRPVKLRKGVFYQG 211
E +I + +I LSAT+ N +E A W+ N +I + RPV L ++ +
Sbjct: 406 VWEEVIIMLPPHVTLILLSATVPNTKEFASWVGRTKKKNIYVISTLKRPVPLEHYLWVKQ 465
Query: 212 --FVFWEDGGSERYNSWEELVYDAVKK---------------GKGAL----VFVNM---- 246
F + G + ++ DA+KK G+GA V NM
Sbjct: 466 NMFKIVDQHGRFLMDGYKS-ANDALKKPDKPVIAKDNKNSARGRGAARGRGVQTNMMRGR 524
Query: 247 ------RRKAEKTALEL------------------AKKVKNYLDRKELRELRELAESLEE 282
R+ T + L K+ + Y+D R+L E E
Sbjct: 525 GSAKSVERRDANTWVHLIGHLHKQNLLPVIVFVFSKKRCEEYVDTLTNRDLNNHQEKSEV 584
Query: 283 NPTNEK-----------------LAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVV 325
+ EK + + L G+A HH GL + +VE F++GL+KV+
Sbjct: 585 HVVIEKAVARLKKEDRLLPQIGRMREMLSRGLAVHHGGLLPIIKEIVEILFQRGLVKVLF 644
Query: 326 ATPTLSAGINTPAFRVIIRDTWRYSEFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVST 385
AT T + G+N PA V+ T ++ + E Q GRAGR D G II+S
Sbjct: 645 ATETFAMGVNMPAKSVVFSGTQKHDGRNFRDLLPGEYTQCSGRAGRRGLDVTGTVIILSR 704
Query: 386 TEEPSLV-IDHYIKGKPEKLFSQLSNESILRSQILALIATFGYSEFKEIYDFLERTFYAH 444
+E P + H I G KL SQ + + IL L+ E I D ++R+F +
Sbjct: 705 SELPDTASLRHMIMGPSSKLISQF---RLTYNMILNLLRV----ETLRIEDMIKRSFSEN 757
Query: 445 QGKDPY-MLEEKIRRIIYFL--LENEFIEVTLEDEIKPLPLGVRTTKLYIDPM------T 495
+ EEKI+ L L+ E +V L+ EIK L + K Y M T
Sbjct: 758 VNQTLVPQHEEKIKSFEEKLSALKKEMSDVDLK-EIKSCLLSSESFKEYTKKMHFRAITT 816
Query: 496 A---KIFKD 501
A +IFKD
Sbjct: 817 ANGKRIFKD 825
>gi|9631809 contains ATP-GTP binding motif; similar to Saccharomyces cervisiae
antiviral protein SKI2, corresponds to Swiss-Prot
Accession Number P35207 [Paramecium bursaria Chlorella
virus 1] >gi|7461244|pir||T17732 helicase-like protein
A241R - Chlorella virus PBCV-1
>gi|1181404|gb|AAC96609.1| (U42580) contains ATP-GTP
binding motif; similar to Saccharomyces cervisiae
antiviral protein SKI2, corresponds to Swiss-Prot
Accession Number P35207 [Paramecium bursaria Chlorella
virus 1]
Length = 725
Score = 143 bits (358), Expect = 5e-33
Identities = 107/389 (27%), Positives = 187/389 (47%), Gaps = 32/389 (8%)
Query: 41 NLLVAIPTASGKTLIAEIAIANKLLEEGGKAVYIVPLKALAEEKFREFKDWERLGL-KVA 99
++ VA T+SGKT+IAE A + +G +Y PLKA++ +K+++F + G V
Sbjct: 27 SVFVAAHTSSGKTIIAEYAYH---ISDGTNVIYTAPLKAISNQKYKDFSS--KFGADNVG 81
Query: 100 MATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSSWIRDVKMLVIDEIHLIGSRDRGATL 159
+ TGD + ++I T E F ++ I++VK ++ DE+H I + RG+
Sbjct: 82 IITGDVVKNET----AKLLIMTTEIFRIMVIKRDQRIQNVKWVIFDEVHYINDKSRGSVW 137
Query: 160 EFIITQMLGRAQIIGLSATIGNPEELAEWLN------AKLIRSDWRPVKLRKGVFYQGFV 213
E I M + + LSAT+ N E + W + ++ + RP+ L+ V + +
Sbjct: 138 EESIILMPDTMRAVFLSATVPNAVEFSNWFSKLKNHPVDVVSTKKRPIPLKYNVIHNSEI 197
Query: 214 F-WEDGGSERYNSWEELVYDAVK-----KGKGALVFVNMRRKAEKTALELAKKV------ 261
E +S EE+ D +K K ++F ++K ++ A +L K V
Sbjct: 198 KDIETFDKILADSPEEITKDTIKMLYNSKLTPCIIFSCNKKKIDRLAQKLYKSVNIMTTY 257
Query: 262 --KNYLDRKELRELRELAESLEENPTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKG 319
KN R+ +L + + E++ ++K + G+ HHAG+ + ++E + KG
Sbjct: 258 ESKNI--RRHFNDLLKKCQVPEDSVYHQKYLEYACEGIGVHHAGVVPYVKEIIEILYCKG 315
Query: 320 LIKVVVATPTLSAGINTPAFRVIIRDTWRYSEFGMERIPVLEVQQMMGRAGRPRYDEVGE 379
+I V+++T T++ G+N PA V+ +++ + E QM GRAGR +DE G
Sbjct: 316 IIPVLISTETVAVGVNGPAHSVLFESLFKFDGLNNRLLREHEFIQMAGRAGRRGFDEEGR 375
Query: 380 AIIVSTTEEPSLVIDHYIKGKPEKLFSQL 408
++ +I I GKPE L S L
Sbjct: 376 VFVLHDPAVERGMISKLINGKPETLHSSL 404
>dbj|BAB02697.1| (AB018114) helicase-like protein [Arabidopsis thaliana]
Length = 1111
Score = 142 bits (355), Expect = 1e-32
Identities = 184/737 (24%), Positives = 311/737 (41%), Gaps = 145/737 (19%)
Query: 41 NLLVAIPTASGKTLIAEIAIANKLLEEGGKAVYIVPLK-ALAEEKFRE----FKDWERLG 95
N++++ PT SGKT++ E+ I + K + K AL EK R+ F W G
Sbjct: 42 NMIISAPTGSGKTVLFELCILRLFSKSISKEGSFLHAKGALKTEKLRDWNQKFNSW---G 98
Query: 96 LKVAMATGD---YDSKDEWLGKYDIIIATAEKFDSLLRH-----GSSWIRDVKMLVIDEI 147
+ TGD Y +K+ + DII+ T EKFD++ R+ G + D+ +++IDE+
Sbjct: 99 ISCLELTGDNETYSTKN--IQDADIILTTPEKFDAVSRYRVTSGGLGFFSDIALVLIDEV 156
Query: 148 HLIGSRDRGATLEFIITQM-------------LGRAQIIGLSATIGNPEELAEWLNA--- 191
HL+ RGA LE I++++ L +++ +SATI N E+LAEWL
Sbjct: 157 HLLND-PRGAALEAIVSRLKILSSNHELRSSTLASVRLLAVSATIPNIEDLAEWLKVPTA 215
Query: 192 --KLIRSDWRPVKLRKGVFYQGFVFWEDGGSERYNSWEELVYDAVKKGKGALVFVNMRRK 249
K + RPVKL VF G +
Sbjct: 216 GIKRFGEEMRPVKLTTKVFGTGLI------------------------------------ 239
Query: 250 AEKTALELAKKVKNYLDRKELRELRELAESLEENPTNEKLAKALLSG---VAFHHAGLGR 306
+ + L ++ + L R++L LRE + + + + + V +H+ GL +
Sbjct: 240 ---SKVMLLPRMTSSLKREQLERLREASPMCSDKQMQSYILQGVTKMSQLVGYHNGGLCQ 296
Query: 307 DERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWRYSEFGMERIPVLE----- 361
+R LVE F G I+V+ T TL+ GIN PA V+I+ T F E+ +E
Sbjct: 297 KDRSLVEGLFLNGDIQVICTTNTLAHGINLPAHTVVIKST---QHFNKEKGHYMEYDRST 353
Query: 362 VQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKGKPEKLFSQLSNESILRSQILAL 421
+ QM GRAGRP +D+ G +I+ T E + ++ + G E + SQL L + A
Sbjct: 354 LLQMSGRAGRPPFDDTG-MVIIMTRRETVHLYENLLNG-CEVVESQLL--PCLIEHLTAE 409
Query: 422 IATFGYSEFKEIYDFLERTF-YAHQGKDP--YML-----EEKIRRIIYFLLENEFIEVTL 473
I S+ ++++ ++ Y K+P Y + ++++ + + L + E++
Sbjct: 410 IVQLTISDITRAIEWMKCSYLYVRMKKNPENYAIKKGIPKDRVEKHLQELCLQKINELSQ 469
Query: 474 EDEI---------KPLPLGVRTTKLYIDPMTAKIFKDTLPRIEKNPNPLGIFHMISLAPD 524
I KP G TK Y+ T K +T + H++ A +
Sbjct: 470 YQMIWTDTDGFVLKPEEPGRLMTKYYLKFETMKYIINTPTSYSLDE----ALHIVCHAEE 525
Query: 525 LTPLSYSKRETSMLEDEYYSLMDRLYFEL-DYENERK---FFRAFKTALVLNAWIN---E 577
++ + + E L D RL F + D + +RK R K ++ N W+
Sbjct: 526 ISWIQLRRNEKKTLNDVNADKEGRLRFHINDNKGKRKKRIQTREEKLFVLANDWLTGDPS 585
Query: 578 VPEGEIVERFNVEPGDIYRIVE-TAEWLIYS---LGEIAKVLEAS---QEVVDYVNTLRL 630
V + + + N + RI E+ IY G ++ L A Q++ D
Sbjct: 586 VHDLSMTQDANSICSNGSRIARCMKEYFIYKKNYKGTLSSTLLAKSLYQKLWD------- 638
Query: 631 RVKHGIREELIPLMELPMVGRKRARALYNAGFKDLESIRNAKPSELLRIEG----IGAKI 686
+ L +LP +G A+AL++ G + E++ A P + + G G I
Sbjct: 639 -------DSPYLLKQLPGIGMVTAKALHSMGVRSFEALAEADPRRIEIVTGRKYPFGNTI 691
Query: 687 VEGIFKYLGK-EVKITE 702
E + K E+K+ E
Sbjct: 692 KESLSSLPPKVEIKVEE 708
>sp|O14232|YDVG_SCHPO PUTATIVE HELICASE C6F12.16C IN CHROMOSOME I >gi|7446189|pir||T11667
probable RNA helicase - fission yeast
(Schizosaccharomyces pombe) >gi|2330862|emb|CAB11099.1|
(Z98533) DEAD box helicase [Schizosaccharomyces pombe]
Length = 1117
Score = 141 bits (352), Expect = 3e-32
Identities = 128/465 (27%), Positives = 211/465 (44%), Gaps = 76/465 (16%)
Query: 40 ENLLVAIPTASGKTLIAEIAIANKLLEEGGKAVYIVPLKALAEEKFREF-KDWERLGLKV 98
E++LV+ T++GKT++AE A+A L ++ + +Y P+KAL+ +K+RE ++ +GL
Sbjct: 214 ESVLVSAHTSAGKTVVAEYAVAQSLRDKQ-RVIYTSPIKALSNQKYRELLAEFGDVGLMT 272
Query: 99 AMATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSSWIRDVKMLVIDEIHLIGSRDRGAT 158
T + D+ ++ T E S+L GS +R+V ++ DEIH + ++RG
Sbjct: 273 GDVTINPDAT--------CLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDKERGVV 324
Query: 159 LEFIITQMLGRAQIIGLSATIGNPEELAEWLN------AKLIRSDWRPVKLRKGVFYQGF 212
E I + ++ + LSATI N + AEW+ ++ +D+RP L+ +F G
Sbjct: 325 WEETIILLPDKSHFVFLSATIPNAMQFAEWITKIHRQPCHVVYTDFRPTPLQHYLFPSGS 384
Query: 213 VFWEDGGSERYNSWEELVYDAV-----------------------KKGKG---------- 239
E+ N EE A+ K GKG
Sbjct: 385 DGIHLVVDEKSNFREENFQRAMSALMEKQGDDPAAMATKGNAKKGKTGKGGVKGPSDIYK 444
Query: 240 ------------ALVFVNMRRKAEKTALELAKKVKNYLDRKEL------RELRELAESLE 281
+VF +R+ E AL+++K N ++L + +L+E
Sbjct: 445 IVKMIMVKNYNPVIVFSFSKRECEALALQMSKLDMNDQTERDLVTTIFNNAVNQLSEKDR 504
Query: 282 ENPTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRV 341
E P E + L G+ HH+GL + ++E F++GL+KV+ AT T S G+N PA V
Sbjct: 505 ELPQIEHILPLLRRGIGIHHSGLLPILKEVIEILFQEGLLKVLFATETFSIGLNMPAKTV 564
Query: 342 IIRDTWRYSEFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKGKP 401
+ + ++ I E QM GRAGR D+ G I++ + V +KG+
Sbjct: 565 VFTNVRKFDGKTFRWISGGEYIQMSGRAGRRGLDDRGIVILMIDEKMDPPVAKSMLKGEA 624
Query: 402 EKLFSQLSNESILRSQILALIATFGYS-EFKEIYDFLERTFYAHQ 445
++L S + + IL L+ G S EF LER F+ Q
Sbjct: 625 DRLDSAF---HLSYNMILNLLRVEGISPEF-----MLERCFFQFQ 661
>emb|CAC11967.1| (AL445065) Large helicase related protein [Thermoplasma
acidophilum]
Length = 894
Score = 140 bits (349), Expect = 6e-32
Identities = 144/518 (27%), Positives = 234/518 (44%), Gaps = 93/518 (17%)
Query: 8 VSEKIKEILRERGIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLEE 67
+ E+I +LR+RGI + PQ E + VLEG+N+L+ PT SGKT A + + ++L E
Sbjct: 8 LDERIIAMLRDRGITDPTDPQ-EQIIPLVLEGKNVLLLSPTGSGKTEAAVLPVFQRILRE 66
Query: 68 GGK---AVYIVPLKALAEEKFREFKDWER-LGLKVAMATGDYDSKDEWL---GKYDIIIA 120
K A+YI PL+AL + D+ R LG+ V + D D+ DI++
Sbjct: 67 KPKKVFALYITPLRALNRDILSRLVDYGRELGIDVQVRHSDMSDADKRRMAESPPDILVT 126
Query: 121 TAEKFDSLL--RHGSSWIRDVKMLVIDEIHLIGSRDRGATLEFIITQ---MLGRAQIIGL 175
T E LL ++ +I +V+++++DE+H +RG+ L + + + G Q IGL
Sbjct: 127 TPESLQILLNGKNLRRFIANVRVVIVDELHDAAENERGSQLSLALERLRDLAGNFQRIGL 186
Query: 176 SATIGNPEELAEWL----NAKLIRSDWRPVKLRKGVFYQGFVFWED--------GGSERY 223
SAT+GNP +LA +L ++I + L+K + V E G +Y
Sbjct: 187 SATVGNPGDLARFLVPNGTCEIIST-----TLKKNMSIDVMVPDESSEEDAEVMGCDRQY 241
Query: 224 NSWEELVYDAVKKGKGALVFVNMRRKAEKTALELAKKVKNYLDRKELRELRELAESLEEN 283
V+D + + G+LVFVN R AE A L K E
Sbjct: 242 AGAILKVWDLINRHAGSLVFVNRRFVAEDLAFRLKLK-------------------FGEI 282
Query: 284 PTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVII 343
P V HH L ++ R E +F+ G +K ++ T +L GI+ +I
Sbjct: 283 P------------VLVHHGSLSKETREFAERSFKNGEVKALICTSSLELGIDVGTANAVI 330
Query: 344 RDTWRYSEFGMERIPVLEVQQMMGRAGRPRY--DEVGEAIIVST----TEEPSLVIDHYI 397
+F R ++ +M+ R GR + + + +V T EE ++D
Sbjct: 331 -------QFNSPR----QINKMIQRIGRSEHWIGKTSKGYVVCTDVIEMEEAIAIVDSIA 379
Query: 398 KGKPEKLFSQLSNESILRSQILALIATFGYSEFKEIYDFLERTF-YAHQGKDPYMLEEKI 456
+GK E + ++ S L +QIL+ I G K ++ ++R++ YA D Y
Sbjct: 380 EGKIENVQIMKNSLSTLANQILSEINAQGKVNVKNFFETVKRSYAYADLPWDEYY----- 434
Query: 457 RRIIYFLLENEFIEVTLEDEIKPLPLGVR--TTKLYID 492
++ FL ++ LEDE+ +G R T K YI+
Sbjct: 435 -SVVSFLASTR--KLWLEDEL----MGRRRNTLKYYIE 465
>gb|AAC67203.1| (AC005171) unknown protein [Arabidopsis thaliana]
Length = 996
Score = 137 bits (341), Expect = 5e-31
Identities = 126/437 (28%), Positives = 199/437 (44%), Gaps = 74/437 (16%)
Query: 40 ENLLVAIPTASGKTLIAEIAIANKLLEEGGKAVYIVPLKALAEEKFRE----FKDWERLG 95
E++LV+ T++GKT +AE AIA ++ + +Y PLKAL+ +K+RE FKD
Sbjct: 85 ESILVSAHTSAGKTAVAEYAIAMAFRDKQ-RVIYTSPLKALSNQKYRELQHEFKD----- 138
Query: 96 LKVAMATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSSWIRDVKMLVIDEIHLIGSRDR 155
V + TGD ++ T E ++L GS +++V ++ DEIH + R+R
Sbjct: 139 --VGLMTGDVTLSPN----ASCLVMTTEILRAMLYRGSEVLKEVAWVIFDEIHYMKDRER 192
Query: 156 GATLEFIITQMLGRAQIIGLSATIGNPEELAEWL------NAKLIRSDWRPVKLRKGVFY 209
G E I + +++ LSAT+ N E AEW+ ++ +D+RP L+ F
Sbjct: 193 GVVWEESIIFLPPAIKMVFLSATMSNATEFAEWICYLHKQPCHVVYTDFRPTPLQHYAFP 252
Query: 210 QG----FVFWEDGGSERYNSWEEL-----------------------------------V 230
G ++ +D R +S+ ++ V
Sbjct: 253 MGGGGLYLVVDDNEQFREDSFVKMQDTFPKPKSNDGKKSANGKSGGRGAKGGGGPGDSDV 312
Query: 231 YDAVK-----KGKGALVFVNMRRKAEKTALELAKKVKNYLDRKELRE------LRELAES 279
Y VK K + ++F RR+ E+ AL ++K N + KE+ E ++ L E
Sbjct: 313 YKIVKMIMERKFEPVIIFSFSRRECEQHALSMSKLDFNTDEEKEVVEQVFNNAMQCLNEE 372
Query: 280 LEENPTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAF 339
P E + L G+A HH+GL + LVE F++GL+K + AT T + G+N PA
Sbjct: 373 DRSLPAIELMLPLLQRGIAVHHSGLLPVIKELVELLFQEGLVKALFATETFAMGLNMPAK 432
Query: 340 RVIIRDTWRYSEFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKG 399
V+ ++ I E QM GRAGR DE G II+ + + + G
Sbjct: 433 TVVFTAVKKWDGDSHRYIGSGEYIQMSGRAGRRGKDERGICIIMIDEQMEMNTLRDMMLG 492
Query: 400 KPEKLFS--QLSNESIL 414
KP L S +LS +IL
Sbjct: 493 KPAPLLSTFRLSYYTIL 509
>gb|AAD38613.1|AF145638_1 (AF145638) l.2.35Df [Drosophila melanogaster]
>gi|7287925|gb|AAF44963.1|AE003406_168 (AE003416)
symbol=l(2)35Df; synonym=BG:DS09217.2;
cDNA=method:''sim4'', score:''1000.0'', desc:''LD10786
Drosophila melanogaster embryo, full length mRNA
sequence from BDGP''; cDNA=method:''sim4'',
score:''990.0'', desc:''LD27110 LD Drosophila melanoga>
>gi|7298249|gb|AAF53481.1| (AE003648) l(2)35Df gene
product [Drosophila melanogaster]
Length = 1055
Score = 135 bits (336), Expect = 2e-30
Identities = 129/476 (27%), Positives = 208/476 (43%), Gaps = 68/476 (14%)
Query: 24 LYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLEEGGKAVYIVPLKALAEE 83
L P Q +A+ + +++LV+ T++GKT++AE AIA L + + +Y P+KAL+ +
Sbjct: 152 LDPFQRQAILC-IDNSQSVLVSAHTSAGKTVVAEYAIAKSLAAKQ-RVIYTTPIKALSNQ 209
Query: 84 KFREFKDWERLGLKVAMATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSSWIRDVKMLV 143
KFREF D + V + TGD +I T E ++L GS +R+V +V
Sbjct: 210 KFREFTDEFK---DVGLVTGDVTINPS----ASCLIMTTEILRNMLYRGSEIMREVGWVV 262
Query: 144 IDEIHLIGSRDRGATLEFIITQMLGRAQIIGLSATIGNPEELAEWL------NAKLIRSD 197
DEIH + ++RG E + + + + LSATI N + AEW+ ++ +D
Sbjct: 263 FDEIHYMRDKERGVVWEETLILLPDNVRYVFLSATIPNARQFAEWVCHLHKQPCHVVYTD 322
Query: 198 WRPVKLRKGVFYQG-----------FVFWED------------------------GGSER 222
+RP L+ +F G F ED GG +
Sbjct: 323 YRPTPLQHYIFPAGGDGIHLIVDEKGQFKEDNFTTAMAVLANAGEAGKGDQKGRHGGIKG 382
Query: 223 YNSWEELVYDAVK-----KGKGALVFVNMRRKAEKTALELAKKVKNYLDRKEL------R 271
N+ + ++ VK ++F ++ E A+++AK N D K+L
Sbjct: 383 TNAGQTNIFKIVKMIMERNFAPVIIFSFSKKDCEIYAMQMAKLDFNTPDEKKLVDEVFNN 442
Query: 272 ELRELAESLEENPTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLS 331
+ L E P E + L G+ HH GL + +E F +GLIK + AT T +
Sbjct: 443 AMDVLTEEDRRLPQVENVLPLLRRGIGIHHGGLLPILKETIEILFGEGLIKALFATETFA 502
Query: 332 AGINTPAFRVIIRDTWRYSEFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSL 391
G+N PA V+ ++ I E QM GRAGR D+ G I++ +
Sbjct: 503 MGLNMPARTVLFTAPRKFDGKKFRWISSGEYIQMAGRAGRRGLDDKGIVILMIDEKVSPA 562
Query: 392 VIDHYIKGKPEKLFSQLSNESILRSQILALIATFGYSEFKEIYDFLERTFYAHQGK 447
V ++GK + + S + + +L L+ E Y LER+FY Q +
Sbjct: 563 VGRDIVQGKADPINSAF---HLTYNMVLNLLRV---EEINPEY-MLERSFYQFQNQ 611
>gi|6322411 RNA helicase; Mtr4p [Saccharomyces cerevisiae]
>gi|1352980|sp|P47047|MTR4_YEAST ATP-DEPENDENT RNA
HELICASE DOB1 (MRNA TRANSPORT REGULATOR MTR4)
>gi|1078374|pir||S56822 SKI2 protein homolog YJL050w -
yeast (Saccharomyces cerevisiae)
>gi|1008185|emb|CAA89341.1| (Z49325) ORF YJL050w
[Saccharomyces cerevisiae]
Length = 1073
Score = 134 bits (335), Expect = 2e-30
Identities = 136/511 (26%), Positives = 229/511 (44%), Gaps = 83/511 (16%)
Query: 27 PQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLEEGGKAVYIVPLKALAEEKFR 86
P + S + GE++LV+ T++GKT++AE AIA L + + +Y P+KAL+ +K+R
Sbjct: 152 PFQDTAISCIDRGESVLVSAHTSAGKTVVAEYAIAQSLKNKQ-RVIYTSPIKALSNQKYR 210
Query: 87 EFKDWERLGLKVAMATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSSWIRDVKMLVIDE 146
E G V + TGD + ++ T E S+L GS +R+V ++ DE
Sbjct: 211 ELL--AEFG-DVGLMTGDITINPD----AGCLVMTTEILRSMLYRGSEVMREVAWVIFDE 263
Query: 147 IHLIGSRDRGATLEFIITQMLGRAQIIGLSATIGNPEELAEWL------NAKLIRSDWRP 200
+H + ++RG E I + + + + LSATI N E AEW+ ++ +++RP
Sbjct: 264 VHYMRDKERGVVWEETIILLPDKVRYVFLSATIPNAMEFAEWICKIHSQPCHIVYTNFRP 323
Query: 201 VKLRKGVF-----------YQGFVFWED-------------------------------G 218
L+ +F + F E+ G
Sbjct: 324 TPLQHYLFPAHGDGIYLVVDEKSTFREENFQKAMASISNQIGDDPNSTDSRGKKGQTYKG 383
Query: 219 GSERYNSWEELVYDAV-----KKGKGALVFVNMRRKAEKTALELAKKVKNYLDRKEL--- 270
GS + ++ + +Y V KK +VF +R E+ AL+++K N D KE
Sbjct: 384 GSAKGDAKGD-IYKIVKMIWKKKYNPVIVFSFSKRDCEELALKMSKLDFNSDDEKEALTK 442
Query: 271 ---RELRELAESLEENPTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVAT 327
+ L E+ E P + + L G+ HH+GL + ++E F++G +KV+ AT
Sbjct: 443 IFNNAIALLPETDRELPQIKHILPLLRRGIGIHHSGLLPILKEVIEILFQEGFLKVLFAT 502
Query: 328 PTLSAGINTPAFRVIIRDTWRYSEFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTE 387
T S G+N PA V+ ++ + E QM GRAGR D+ G I++ +
Sbjct: 503 ETFSIGLNMPAKTVVFTSVRKWDGQQFRWVSGGEYIQMSGRAGRRGLDDRGIVIMMIDEK 562
Query: 388 EPSLVIDHYIKGKPEKLFSQLSNESILRSQILALIATFGYS-EFKEIYDFLERTFYAHQG 446
V +KG+ ++L S + + IL L+ G S EF LE +F+ Q
Sbjct: 563 MEPQVAKGMVKGQADRLDSAF---HLGYNMILNLMRVEGISPEF-----MLEHSFFQFQN 614
Query: 447 K-DPYMLEEKIRRIIYFLLENEFIEVTLEDE 476
++E+K+ L+ +F + +EDE
Sbjct: 615 VISVPVMEKKLAE-----LKKDFDGIEVEDE 640
>gb|AAD39319.1|AC007258_8 (AC007258) Very similar to helicases [Arabidopsis thaliana]
Length = 988
Score = 134 bits (333), Expect = 4e-30
Identities = 109/423 (25%), Positives = 191/423 (44%), Gaps = 64/423 (15%)
Query: 39 GENLLVAIPTASGKTLIAEIAIANKLLEEGGKAVYIVPLKALAEEKFREFKD-WERLGLK 97
GE+++V+ T++GKT++A AIA L +E + +Y P+KAL+ +K+R+FK+ + +GL
Sbjct: 82 GESVMVSAHTSAGKTVVASYAIAMSL-KENQRVIYTSPIKALSNQKYRDFKEEFSDVGLM 140
Query: 98 VAMATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSSWIRDVKMLVIDEIHLIGSRDRGA 157
T D ++ ++ T E S+ GS +R+V ++ DE+H + +RG
Sbjct: 141 TGDVTIDPNAS--------CLVMTTEILRSMQYKGSEIMREVAWIIFDEVHYMRDSERGV 192
Query: 158 TLEFIITQMLGRAQIIGLSATIGNPEELAEWL------NAKLIRSDWRPVKLRKGVFYQG 211
E I ++ + LSAT+ N +E A+W+ ++ +D+RP L+ VF G
Sbjct: 193 VWEESIVMAPKNSRFVFLSATVPNAKEFADWVAKVHQQPCHIVYTDYRPTPLQHYVFPAG 252
Query: 212 -----------FVFWEDGGSERYNSWEELVYDAVKKGKG--------------------- 239
F ED + N+ K+ G
Sbjct: 253 GNGLYLVVDEKSKFHEDSFQKSLNALVPTNESDKKRDNGKFQKGLVIGKLGEESDIFKLV 312
Query: 240 ----------ALVFVNMRRKAEKTALELAKKVKNYLDRKELRE------LRELAESLEEN 283
++F +++ E A++++K V N D K+ E + L++ ++
Sbjct: 313 KMIIQRQYDPVILFSFSKKECEALAMQMSKMVLNSDDEKDAVETIFASAIDMLSDDDKKL 372
Query: 284 PTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVII 343
P + L G+ HH+GL + ++E F++GLIK + AT T S G+N PA V+
Sbjct: 373 PQVSNILPILKRGIGVHHSGLLPILKEVIEILFQEGLIKCLFATETFSIGLNMPAKTVVF 432
Query: 344 RDTWRYSEFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKGKPEK 403
+ ++ + E QM GRAGR D+ G I++ + V +KG +
Sbjct: 433 TNVRKFDGDKFRWLSSGEYIQMSGRAGRRGIDKRGICILMVDEKMEPAVAKSMLKGSADS 492
Query: 404 LFS 406
L S
Sbjct: 493 LNS 495
>sp|P42285|Y052_HUMAN HYPOTHETICAL PROTEIN KIAA0052
Length = 1045
Score = 131 bits (326), Expect = 3e-29
Identities = 126/467 (26%), Positives = 211/467 (44%), Gaps = 66/467 (14%)
Query: 28 QAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLEEGGKAVYIVPLKALAEEKFRE 87
Q EA+ V +++LV+ T++GKT+ AE AIA L E+ + ++ P+KAL+ +K+RE
Sbjct: 148 QREAIQC-VDNNQSVLVSAHTSAGKTVCAEYAIALALREKQ-RVIFTSPIKALSNQKYRE 205
Query: 88 -FKDWERLGLKVAMATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSSWIRDVKMLVIDE 146
+++++ +GL TGD ++ T E S+L GS +R+V ++ DE
Sbjct: 206 MYEEFQDVGLM----TGDVTINPT----ASCLVMTTEILRSMLYRGSEVMREVAWVIFDE 257
Query: 147 IHLIGSRDRGATLEFIITQMLGRAQIIGLSATIGNPEELAEWL------NAKLIRSDWRP 200
IH + +RG E I + + LSATI N + AEW+ +I +D+RP
Sbjct: 258 IHYMRDSERGVVWEETIILLPDNVHYVFLSATIPNARQFAEWICHLHKQPCHVIYTDYRP 317
Query: 201 VKLRKGVFYQG-----FVFWEDGG--SERYNSWEELVYDAVKKGKG-------------- 239
L+ +F G V E+G + +N+ +++ DA KG
Sbjct: 318 TPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGDQKGRKGGTKGPSN 377
Query: 240 ---------------ALVFVNMRRKAEKTALELAKKVKNYLDRKELRE------LRELAE 278
++F ++ E AL++ K N + K++ E + L++
Sbjct: 378 VFKIVKMIMERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFSNAIDCLSD 437
Query: 279 SLEENPTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPA 338
++ P E + L G+ HH GL + +E F +GLIK + AT T + GIN PA
Sbjct: 438 EDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGINMPA 497
Query: 339 FRVIIRDTWRYSEFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIK 398
V+ + ++ I E QM GRAGR D+ G I++ + + +K
Sbjct: 498 RTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGKQLLK 557
Query: 399 GKPEKLFSQLSNESILRSQILALIATFGYSEFKEIYDFLERTFYAHQ 445
G + L S + + +L L+ E Y LE++FY Q
Sbjct: 558 GSADPLNSAF---HLTYNMVLNLLRV---EEINPEY-MLEKSFYQFQ 597
>dbj|BAA06124.2| (D29641) KIAA0052 protein [Homo sapiens]
Length = 1046
Score = 131 bits (326), Expect = 3e-29
Identities = 126/467 (26%), Positives = 211/467 (44%), Gaps = 66/467 (14%)
Query: 28 QAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLEEGGKAVYIVPLKALAEEKFRE 87
Q EA+ V +++LV+ T++GKT+ AE AIA L E+ + ++ P+KAL+ +K+RE
Sbjct: 148 QREAIQC-VDNNQSVLVSAHTSAGKTVCAEYAIALALREKQ-RVIFTSPIKALSNQKYRE 205
Query: 88 -FKDWERLGLKVAMATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSSWIRDVKMLVIDE 146
+++++ +GL TGD ++ T E S+L GS +R+V ++ DE
Sbjct: 206 MYEEFQDVGLM----TGDVTINPT----ASCLVMTTEILRSMLYRGSEVMREVAWVIFDE 257
Query: 147 IHLIGSRDRGATLEFIITQMLGRAQIIGLSATIGNPEELAEWL------NAKLIRSDWRP 200
IH + +RG E I + + LSATI N + AEW+ +I +D+RP
Sbjct: 258 IHYMRDSERGVVWEETIILLPDNVHYVFLSATIPNARQFAEWICHLHKQPCHVIYTDYRP 317
Query: 201 VKLRKGVFYQG-----FVFWEDGG--SERYNSWEELVYDAVKKGKG-------------- 239
L+ +F G V E+G + +N+ +++ DA KG
Sbjct: 318 TPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGDQKGRKGGTKGPSN 377
Query: 240 ---------------ALVFVNMRRKAEKTALELAKKVKNYLDRKELRE------LRELAE 278
++F ++ E AL++ K N + K++ E + L++
Sbjct: 378 VFKIVKMIMERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFSNAIDCLSD 437
Query: 279 SLEENPTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPA 338
++ P E + L G+ HH GL + +E F +GLIK + AT T + GIN PA
Sbjct: 438 EDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGINMPA 497
Query: 339 FRVIIRDTWRYSEFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIK 398
V+ + ++ I E QM GRAGR D+ G I++ + + +K
Sbjct: 498 RTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGKQLLK 557
Query: 399 GKPEKLFSQLSNESILRSQILALIATFGYSEFKEIYDFLERTFYAHQ 445
G + L S + + +L L+ E Y LE++FY Q
Sbjct: 558 GSADPLNSAF---HLTYNMVLNLLRV---EEINPEY-MLEKSFYQFQ 597
>sp|O13799|YE02_SCHPO PUTATIVE HELICASE C17H9.02 IN CHROMOSOME I >gi|7492640|pir||T37868
probable helicase - fission yeast (Schizosaccharomyces
pombe) >gi|2330709|emb|CAB11211.1| (Z98597) putative
helicase [Schizosaccharomyces pombe]
Length = 1030
Score = 129 bits (320), Expect = 1e-28
Identities = 127/504 (25%), Positives = 225/504 (44%), Gaps = 74/504 (14%)
Query: 23 ELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLEEGGKAVYIVPLKALAE 82
EL P Q+ A+ V E++LV+ T++GKT+IAE AIA + L+ + +Y P+K+L+
Sbjct: 125 ELDPFQSTAIKC-VERMESVLVSAHTSAGKTVIAEYAIA-QALKNRQRVIYTSPIKSLSN 182
Query: 83 EKFREFKDWERLGLKVAMATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSSWIRDVKML 142
+K+RE G V + TGD +I T E ++L S + ++ +
Sbjct: 183 QKYRELLS--EFG-DVGLMTGDVSINPS----ASCLIMTTEILRAMLYKNSEIMHEIAWV 235
Query: 143 VIDEIHLIGSRDRGATLEFIITQMLGRAQIIGLSATIGNPEELAEWLN------AKLIRS 196
+ DE+H + +DRG E + + + I LSAT+ N + A W++ ++ +
Sbjct: 236 IFDEVHYMRDKDRGVVWEETLILLPDAIRFIFLSATLPNALQFARWISEIHKQPCHVVYT 295
Query: 197 DWRPVKLRKGVFYQG----FVFWEDGGSERYNSWEELV---------------YDAVKKG 237
D+RP L+ ++ QG ++ ++ + ++++++ VKK
Sbjct: 296 DYRPTPLQHFIYPQGADGIYMLVDEKNKFKTENFKKVLEVLDHSTRQENYSKSSKKVKKS 355
Query: 238 KGALVFVNM---------------RRKAEKTALELAKKVKNYLDRKEL------RELREL 276
+NM +++ E A + K N + KEL + +L
Sbjct: 356 SSLERIINMVLSNRYDPIIVFCFSKKECEINAHQFGKLDLNDTENKELVTEIFDSAINQL 415
Query: 277 AESLEENPTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINT 336
+E E++ LL G+ HH+GL + LVE F++GL++++ AT T S G+N
Sbjct: 416 SEEDRGLRQFEEMRSLLLRGIGIHHSGLLPILKELVEILFQEGLVRILFATETFSIGLNM 475
Query: 337 PAFRVIIRDTWRYSEFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHY 396
PA V+ ++S + E QM GRAGR D G +I++
Sbjct: 476 PARTVLFTKAQKFSGNNFRWLTSGEYMQMSGRAGRRGIDTKGLSIVILDQSIDEQAARCL 535
Query: 397 IKGKPEKLFS--QLSNESILRSQILALIATFGYSEFKEIYDFLERTFYAHQGKD--PYML 452
+ G+ + L S LS IL + I+ D L+++FY Q + P +
Sbjct: 536 MNGQADVLNSAFHLSYGMILNLMRIEEISP---------EDILKKSFYQFQNMESLPLIK 586
Query: 453 EEKIRRIIYFLLENEFIEVTLEDE 476
EE ++ L+NE + + +E
Sbjct: 587 EELMQ------LKNEETSINIPNE 604
>gb|AAG19610.1| (AE005050) ATP-dependent helicase; HelA [Halobacterium sp. NRC-1]
Length = 946
Score = 127 bits (317), Expect = 3e-28
Identities = 123/493 (24%), Positives = 218/493 (43%), Gaps = 67/493 (13%)
Query: 7 NVSEKIKEILRERGIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLE 66
++ +++ L ERG PQ A+ + + +G N LV PT +GKT A + + + L+
Sbjct: 14 HLGSEVRNALSERGFTTPTEPQRRAVPA-LADGRNGLVVAPTGTGKTETAMLPVFDALVS 72
Query: 67 EGGK-----AVYIVPLKALAEEKFREFKDW--ERLGLKVAMATGD---YDSKDEWLGKYD 116
+GG A+Y+ PL+AL + RE DW E LGL+V + GD Y + + D
Sbjct: 73 DGGPPDGFGALYVTPLRALNRD-MRERLDWWGETLGLEVDVRHGDTTDYQRRQQATDPPD 131
Query: 117 IIIATAEKFDSLLRHGS--SWIRDVKMLVIDEIHLIGSRDRGATLEFIITQML---GRAQ 171
+++ T E ++L + + DV+ +V+DE+H + RGA L + +++ GR Q
Sbjct: 132 VLVTTPETLQAMLTGSTLRDGLADVEHVVVDEVHELAGAKRGAQLAIGLERLVEVAGRVQ 191
Query: 172 IIGLSATIGNPEELAEWL----NAKLIRSDWRPVKLRKGVFYQGFVFWEDGGSERYNSWE 227
IGLSAT+G+P E+ +L ++I D + + E
Sbjct: 192 RIGLSATVGDPHEIGAFLTGGRGCEIIEVDVT-------------------SNVSFEVRE 232
Query: 228 ELVYDAVKKGKGALVFVNMRRKAEKTALELAKKVKNYLDRKELRELRELAESLEENPTNE 287
V DA ++ L+ + E+ + + L R+ AE+L
Sbjct: 233 PAVTDADERLASELLTTPAMASHVRAIREIVDRHDSVL---IFVNTRQTAEALGSR---- 285
Query: 288 KLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTW 347
K L + + HH L +D R+ VED F+ G + ++ T ++ GI+ ++
Sbjct: 286 --FKELDANIGVHHGSLSKDARIDVEDRFKSGDLDGLLCTSSMELGIDVGGIDHVV---- 339
Query: 348 RYSEFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSL----VIDHYIKGKPEK 403
++ R V + Q +GRAG R D V E +++ + + +L V D +G E
Sbjct: 340 ---QYNSPR-EVKRLLQRVGRAGHSR-DAVSEGTVITGSTDDTLEALAVADRANEGAVED 394
Query: 404 LFSQLSNESILRSQILALIATFGYSEFKEIYDFLERTFYAHQGKDPYMLEEKIRRIIYFL 463
+ + +QI+ ++ G +E Y+ + R + Q + EE R + L
Sbjct: 395 TQVHHGSLDTVANQIVGVVMDVGETEAWHAYNIITRAYPFKQ-----LTEETFRAVAMEL 449
Query: 464 LENEFIEVTLEDE 476
N + V +D+
Sbjct: 450 HRNRVVYVDEDDD 462
>sp|Q23223|YH2O_CAEEL PUTATIVE HELICASE W08D2.7 IN CHROMOSOME IV >gi|7509133|pir||T26282
hypothetical protein W08D2.7 - Caenorhabditis elegans
>gi|3880559|emb|CAA94235.1| (Z70271) predicted using
Genefinder~Similarity to Human myeloid cell line protein
2 (SW:YY02_HUMAN), contains similarity to Pfam domain:
PF00270 (DEAD/DEAH box helicase), Score=101.8,
E-value=9e-32, N=1~cDNA EST yk5c6.3 comes from this
gene~cDNA EST yk>
Length = 1026
Score = 126 bits (314), Expect = 7e-28
Identities = 121/451 (26%), Positives = 204/451 (44%), Gaps = 67/451 (14%)
Query: 14 EILRERGIE--ELYPPQAEALTSGVL----EGENLLVAIPTASGKTLIAEIAIANKLLEE 67
E+ G E + YP Q +A + +++LV+ T++GKT++A AIA K L E
Sbjct: 109 ELRENSGTEPAKYYPFQLDAFQKQAILCIDNNQSVLVSAHTSAGKTVVATYAIA-KCLRE 167
Query: 68 GGKAVYIVPLKALAEEKFREFKDWERLGLKVAMATGDYDSKDEWLGKYDIIIATAEKFDS 127
+ +Y P+KAL+ +K+RE ++ + V + TGD + ++ T E S
Sbjct: 168 KQRVIYTSPIKALSNQKYRELEEEFK---DVGLMTGDVTLNPD----ASCLVMTTEILRS 220
Query: 128 LLRHGSSWIRDVKMLVIDEIHLIGSRDRGATLEFIITQMLGRAQIIGLSATIGNPEELAE 187
+L GS +++V +V DEIH + ++RG E I M + LSATI N + A+
Sbjct: 221 MLYRGSEIMKEVGWVVYDEIHYMRDKERGVVWEETIILMSKNIKQAFLSATIPNARQFAQ 280
Query: 188 WLNA------KLIRSDWRPVKLRKGVFYQG-----------FVFWED------------- 217
W+ + ++ +D+RP L+ ++ G F ED
Sbjct: 281 WVASIKQQPVNVVYTDYRPTPLQHWIYPVGGEGMYEVVNVKGEFREDKFRDAMSGLATAG 340
Query: 218 ------------GGSERYNSWEELVYD-AVKKGKGALVFVNMRRKAEKTALELAKKVKNY 264
GG++ ++ +++ A G +VF R++ E A+ L K ++
Sbjct: 341 DSAGSFNKRRTGGGTQGDSNVLKIIRSVASNDGLNCIVFSFSRKECESYAISL--KDMDF 398
Query: 265 LDRKELRELRELAES--LEENPTNEKLAK------ALLSGVAFHHAGLGRDERVLVEDNF 316
E ++ + ES + +P ++KL + L G+ HH+GL + +E F
Sbjct: 399 NKDHEKGMVKSVYESAIAQLSPEDQKLPQILNILPLLRRGIGVHHSGLMPILKETIEILF 458
Query: 317 RKGLIKVVVATPTLSAGINTPAFRVIIRDTWRYSEFGMERIPVLEVQQMMGRAGRPRYDE 376
+GL+KV+ AT T S G+N PA V+ ++ I E QM GRAGR D+
Sbjct: 459 GEGLVKVLFATETFSMGLNMPARTVVFTSARKFDGSDNRYITSGEYIQMAGRAGRRGKDD 518
Query: 377 VGEAIIVSTTEEPSLVIDHYIKGKPEKLFSQ 407
G I++ + + IKG + L SQ
Sbjct: 519 RGTVILMVDSAMSADDAKQIIKGATDPLNSQ 549
>sp|Q10701|HELY_MYCTU PUTATIVE HELICASE HELY >gi|7478108|pir||G70767 probable helicase
helY - Mycobacterium tuberculosis (strain H37RV)
>gi|1370259|emb|CAA98204.1| (Z73966) helY [Mycobacterium
tuberculosis]
Length = 906
Score = 124 bits (309), Expect = 3e-27
Identities = 113/421 (26%), Positives = 184/421 (42%), Gaps = 73/421 (17%)
Query: 34 SGVLEGENLLVAIPTASGKTLIAEIAIANKLLEEGGKAVYIVPLKALAEEKFREFKDWER 93
S + G +LV PT +GKT++ E A+ + L G K Y PLKAL+ +K + R
Sbjct: 27 SALERGHGVLVCAPTGAGKTVVGEFAV-HLALAAGSKCFYTTPLKALSNQKHTDLT--AR 83
Query: 94 LGL-KVAMATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSSWIRDVKMLVIDEIHLIGS 152
G ++ + TGD G +++ T E ++L S ++ + +V+DE+H +
Sbjct: 84 YGRDQIGLLTGDLSVN----GNAPVVVMTTEVLRNMLYADSPALQGLSYVVMDEVHFLAD 139
Query: 153 RDRGATLEFIITQMLGRAQIIGLSATIGNPEELAEWL-----NAKLIRSDWRPVKLRKGV 207
R RG E +I Q+ +++ LSAT+ N EE W+ + ++ + RPV L + V
Sbjct: 140 RMRGPVWEEVILQLPDDVRVVSLSATVSNAEEFGGWIQTVRGDTTVVVDEHRPVPLWQHV 199
Query: 208 FYQGFVF-------WEDGGSERYNSWEELV--------------YDAVKKGKG------- 239
+F E G + N EL+ + ++G G
Sbjct: 200 LVGKRMFDLFDYRIGEAEGQPQVN--RELLRHIAHRREADRMADWQPRRRGSGRPGFYRP 257
Query: 240 -----------------ALVFVNMRRKAEKTALELAKKVKNYLDRKELRELRELAESLEE 282
A+ FV R + + + +E + E+ +
Sbjct: 258 PGRPEVIAKLDAEGLLPAITFVFSRAGCDAAVTQCLRSPLRLTSEEERARIAEVIDHRCG 317
Query: 283 NPTNEKLA--------KALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGI 334
+ + LA + LL G+A HHAG+ R VE+ F GL+K V AT TL+ GI
Sbjct: 318 DLADSDLAVLGYYEWREGLLRGLAAHHAGMLPAFRHTVEELFTAGLVKAVFATETLALGI 377
Query: 335 NTPAFRVIIRDTWRYSEFGMERIPVL--EVQQMMGRAGRPRYDEVGEAIIVSTTE-EPSL 391
N PA V++ +++ G + +P+ E Q+ GRAGR D G A+++ E EPS
Sbjct: 378 NMPARTVVLERLVKFN--GEQHMPLTPGEYTQLTGRAGRRGIDVEGHAVVIWHPEIEPSE 435
Query: 392 V 392
V
Sbjct: 436 V 436
>emb|CAA22943.1| (AL035310) putative helicase [Mycobacterium leprae]
Length = 920
Score = 123 bits (305), Expect = 8e-27
Identities = 112/420 (26%), Positives = 181/420 (42%), Gaps = 75/420 (17%)
Query: 39 GENLLVAIPTASGKTLIAEIAIANKLLEEGGKAVYIVPLKALAEEKFREFKDWERLGL-K 97
G +LV PT +GKT++ E A+ + L GGK Y PLKAL+ +K+ + R G +
Sbjct: 32 GHGVLVCAPTGAGKTVVGEFAV-HLALAAGGKCFYTTPLKALSNQKYTDLT--ARYGRNR 88
Query: 98 VAMATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSSWIRDVKMLVIDEIHLIGSRDRGA 157
+ + TGD G +++ T E ++L S ++ + +V+DE+H I R RG
Sbjct: 89 IGLLTGDQSVN----GDSPVVVMTTEVLRNMLYADSFALQGLSHVVMDEVHFIADRMRGP 144
Query: 158 TLEFIITQMLGRAQIIGLSATIGNPEELAEWL-----NAKLIRSDWRPVKLRKGVFYQGF 212
E +I + +++ LSAT+ N EE W+ + ++ + RPV L + V
Sbjct: 145 VWEEVILHLPDDVRMVSLSATVSNAEEFGGWVQTVRGDTTVVVDEHRPVPLWQHVLVGKR 204
Query: 213 VF---------------------------------WED-------GGSER---YNSWEEL 229
+F W + G R Y S
Sbjct: 205 LFDLFDYDSNVDQSPVNPNLLRHIAHCREADRMSDWRNPRRRAGRGSGVRPRFYRSLARP 264
Query: 230 VYDAVKKGKG---ALVFVNMRRKAEKTALELAKKVKNYLDRKELRELRELAESLEENPTN 286
A+ +G A+ FV R + + + +E ++ E+ + + +
Sbjct: 265 EVIAILDAEGLLPAITFVFSRFGCDAAVQQCLRSPLRLTSEEERAQIAEVIDHRCGDLAD 324
Query: 287 EKLA--------KALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPA 338
LA + LL G+A HHAG+ R VE+ F GL+K V AT TL+ GIN PA
Sbjct: 325 ADLAVLGYYEWREGLLRGLAAHHAGMLPAFRHAVEELFTAGLVKAVFATETLALGINMPA 384
Query: 339 FRVIIRDTWRYSEFGMERIPVL--EVQQMMGRAGRPRYDEVGEAIIV----STTEEPSLV 392
V++ +++ G + +P+ E Q+ GRAGR D G A+++ T PS V
Sbjct: 385 RTVVLERLVKFN--GKQHVPLTPGEYTQLTGRAGRRGIDVEGHAVVIWHPSEDTSGPSAV 442
>gi|10946650 similar to SKI2W protein [Mus musculus] >gi|2944423|gb|AAC05282.1|
(AF049850) hypothetical protein [Mus musculus]
Length = 1236
Score = 122 bits (304), Expect = 1e-26
Identities = 121/460 (26%), Positives = 202/460 (43%), Gaps = 73/460 (15%)
Query: 40 ENLLVAIPTASGKTLIAEIAIANKLLEEGGKAVYIVPLKALAEEKFREFKDWERLGLKVA 99
+++ VA T++GKT++AE AIA + + +Y P+KAL+ +KFR+F++ G V
Sbjct: 315 DSVFVAAHTSAGKTVVAEYAIA-LAQKHMTRTIYTSPIKALSNQKFRDFRN--TFG-DVG 370
Query: 100 MATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSSWIRDVKMLVIDEIHLIGSRDRGATL 159
+ TGD E +I T E S+L GS IRD++ ++ DE+H I +RG
Sbjct: 371 LLTGDVQLHPE----ASCLIMTTEILRSMLYSGSDVIRDLEWVIFDEVHYINDAERGVVW 426
Query: 160 EFIITQMLGRAQIIGLSATIGNPEELAEWL------NAKLIRSDWRPVKLR--------- 204
E ++ + II LSAT+ N E A+W+ +I + RPV L
Sbjct: 427 EEVLIMLPEHVSIILLSATVPNALEFADWIGRLKRRQIYVISTVARPVPLEHYLFTGNSP 486
Query: 205 ------------KGVFY-QGFVFWEDGGSERYNSWEELV---------YDAVKKGKGALV 242
+G F+ QG+ + ER + + A +G +
Sbjct: 487 KTQGELFLLLDSRGAFHTQGYYAAVEAKKERMSKHAQTFGAKQPTHQGGPAQDRGVYLSL 546
Query: 243 FVNMRRKAE-------------------KTALEL-AKKVKNYLDRKELRELRELAESLEE 282
++R +A+ T+L+L K+ + R L L S +
Sbjct: 547 LASLRTRAQLPVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARLRGSDRQ 606
Query: 283 NPTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVI 342
P +++ L G+ HH+G+ + +VE F +GL+KV+ AT T + G+N PA V+
Sbjct: 607 LPQVLHMSELLRRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNMPARTVV 666
Query: 343 IRDTWRYSEFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLV-IDHYIKGKP 401
++ + E QM GRAGR D G I++ P + + + GKP
Sbjct: 667 FDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMADLHRMMMGKP 726
Query: 402 EKLFSQLSNESILRSQILALIATFGYSEFKEIYDFLERTF 441
+L SQ + + IL L+ + + D ++R+F
Sbjct: 727 SQLQSQF---RLTYTMILNLLRV----DALRVEDMMKRSF 759
>gi|11498749 large helicase-related protein (lhr-1) [Archaeoglobus fulgidus]
>gi|7446074|pir||D69393 large helicase-related protein
(lhr-1) homolog - Archaeoglobus fulgidus
>gi|2649437|gb|AAB90094.1| (AE001024) large
helicase-related protein (lhr-1) [Archaeoglobus
fulgidus]
Length = 892
Score = 122 bits (303), Expect = 1e-26
Identities = 118/454 (25%), Positives = 210/454 (45%), Gaps = 64/454 (14%)
Query: 8 VSEKIKEILRERGIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLE- 66
++++++E L GIEEL Q EA +L G+++L+ PT SGKT A I I +L+
Sbjct: 2 LNQRLREALSAAGIEELTELQLEAFRK-ILSGKDVLIIAPTGSGKTEAAIIPIFEAMLKM 60
Query: 67 ---EGGKAVYIVPLKALAEEKFREFKDW-ERLGLKVAMATGDY-DSKDEWLGKYD--III 119
EG A+YI PL+AL + R + E LG++V + GD DS+ + ++I
Sbjct: 61 EKPEGIVAIYITPLRALNRDMLRRIRGIAEFLGIRVDVRHGDTPDSQRARQSRKPPHLLI 120
Query: 120 ATAEKFDSLL--RHGSSWIRDVKMLVIDEIHLIGSRDRGATLEFIITQM--LGRAQIIGL 175
T E F L ++ +++V+ +V+DEIH + +RG L + ++ + R Q IGL
Sbjct: 121 TTPETFQILFLGKNLRKALKNVRYVVVDEIHELIDSERGVQLSVALERLREMARFQTIGL 180
Query: 176 SATIGNPEELAEWLNAKLIRSDWRPVKLRKGVFYQGFV----FWEDGGSERYNSWEELVY 231
SAT+ P+ ++ ++ A +W+ K + + V + G + +
Sbjct: 181 SATVSRPKLVSRFVGADAEVLEWKAEKEYEIEVVKPEVDEKLAAKLGVDAEIAGELKFIA 240
Query: 232 DAVKKGKGALVFVNMRRKAEKTALELAKKVKNYLDRKELRELRELAESLEENPTNEKLAK 291
DAVK+ AL+FVN R+ AE ++L K
Sbjct: 241 DAVKEHGSALIFVNTRQTAEALGIKLKK-------------------------------- 268
Query: 292 ALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWRYSE 351
L V HH L R+ RV E+ F KG + ++ T ++ GI+ +++ +
Sbjct: 269 --LIDVEVHHGSLSRETRVEAEERFAKGELDALICTSSMELGIDIGHVNLVV-------Q 319
Query: 352 FGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTT----EEPSLVIDHYIKGKPEKLFSQ 407
+ R V VQ+ +GR+G V + +V+++ E ++++ +G E
Sbjct: 320 YNSPRQAVRLVQR-VGRSGH-GLGRVSKGYVVASSFDDILESAVIVRRAKEGLLEDAEIH 377
Query: 408 LSNESILRSQILALIATFGYSEFKEIYDFLERTF 441
+ +L +QI AL +G + ++ + ++R F
Sbjct: 378 FKSFDVLANQICALALEYGRIDAEKAHRIVKRAF 411
>pir||S56752 helicase SKI2W - human >gi|4379045|emb|CAA88733.1| (Z48796)
helicase [Homo sapiens]
Length = 1246
Score = 121 bits (301), Expect = 2e-26
Identities = 120/460 (26%), Positives = 203/460 (44%), Gaps = 73/460 (15%)
Query: 40 ENLLVAIPTASGKTLIAEIAIANKLLEEGGKAVYIVPLKALAEEKFREFKDWERLGLKVA 99
+++ VA T++GKT++AE AIA + + +Y P+KAL+ +KFR+F++ G V
Sbjct: 326 DSVFVAAHTSAGKTVVAEYAIA-LAQKHMTRTIYTSPIKALSNQKFRDFRN--TFG-DVG 381
Query: 100 MATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSSWIRDVKMLVIDEIHLIGSRDRGATL 159
+ TGD E +I T E S+L GS IRD++ ++ DE+H I +RG
Sbjct: 382 LLTGDVQLHPE----ASCLIMTTEILRSMLYSGSDVIRDLEWVIFDEVHYINDVERGVVW 437
Query: 160 EFIITQMLGRAQIIGLSATIGNPEELAEWL------NAKLIRSDWRPVKLR--------- 204
E ++ + II LSAT+ N E A+W+ +I + RPV L
Sbjct: 438 EEVLIMLPDHVSIILLSATVPNALEFADWIGRLKRRQIYVISTVTRPVPLEHYLFTGNSS 497
Query: 205 ------------KGVFY-QGFVFWEDGGSERYNSWEELV---------YDAVKKGKGALV 242
+G F+ +G+ + ER + + A +G +
Sbjct: 498 KTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHAQTFGAKQPTHQGGPAQDRGVYLSL 557
Query: 243 FVNMRRKAE-------------------KTALEL-AKKVKNYLDRKELRELRELAESLEE 282
++R +A+ T+L+L K+ + R L L S +
Sbjct: 558 LASLRTRAQLPVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARLRGSDRQ 617
Query: 283 NPTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVI 342
P ++++ L G+ HH+G+ + +VE F +GL+KV+ AT T + G+N PA V+
Sbjct: 618 LPQVLQMSELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNMPARTVV 677
Query: 343 IRDTWRYSEFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLV-IDHYIKGKP 401
++ + E QM GRAGR D G I++ P + + + GKP
Sbjct: 678 FDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMADLHRMMMGKP 737
Query: 402 EKLFSQLSNESILRSQILALIATFGYSEFKEIYDFLERTF 441
+L SQ + + IL L+ + + D ++R+F
Sbjct: 738 SQLQSQF---RLTYTMILNLLRV----DALRVEDMMKRSF 770
>gi|11417770 superkiller viralicidic activity 2 (S. cerevisiae homolog)-like
[Homo sapiens] >gi|2347134|gb|AAB67978.1|AAB67978
(AF019413) helicase [Homo sapiens]
Length = 1246
Score = 120 bits (299), Expect = 4e-26
Identities = 120/460 (26%), Positives = 202/460 (43%), Gaps = 73/460 (15%)
Query: 40 ENLLVAIPTASGKTLIAEIAIANKLLEEGGKAVYIVPLKALAEEKFREFKDWERLGLKVA 99
+++ VA T++GKT++AE AIA + + +Y P+KAL+ +KFR+F++ G V
Sbjct: 326 DSVFVAAHTSAGKTVVAEYAIA-LAQKHMTRTIYTSPIKALSNQKFRDFRN--TFG-DVG 381
Query: 100 MATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSSWIRDVKMLVIDEIHLIGSRDRGATL 159
+ TGD E +I T E S+L GS IRD++ ++ DE+H I +RG
Sbjct: 382 LLTGDVQLHPE----ASCLIMTTEILRSMLYSGSDVIRDLEWVIFDEVHYINDVERGVVW 437
Query: 160 EFIITQMLGRAQIIGLSATIGNPEELAEWL------NAKLIRSDWRPVKLR--------- 204
E ++ + II LSAT+ N E A+W+ +I + RPV L
Sbjct: 438 EEVLIMLPDHVSIILLSATVPNALEFADWIGRLKRRQIYVISTVTRPVPLEHYLFTGNSS 497
Query: 205 ------------KGVFY-QGFVFWEDGGSERYNSWEELV---------YDAVKKGKGALV 242
+G F+ +G+ + ER + + A +G +
Sbjct: 498 KTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHAQTFGAKQPTHQGGPAQDRGVYLSL 557
Query: 243 FVNMRRKAE-------------------KTALEL-AKKVKNYLDRKELRELRELAESLEE 282
++R +A+ T+L+L K+ + R L L S +
Sbjct: 558 LASLRTRAQLPVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARLRGSDRQ 617
Query: 283 NPTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVI 342
P +++ L G+ HH+G+ + +VE F +GL+KV+ AT T + G+N PA V+
Sbjct: 618 LPQVLHMSELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNMPARTVV 677
Query: 343 IRDTWRYSEFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLV-IDHYIKGKP 401
++ + E QM GRAGR D G I++ P + + + GKP
Sbjct: 678 FDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMADLHRMMMGKP 737
Query: 402 EKLFSQLSNESILRSQILALIATFGYSEFKEIYDFLERTF 441
+L SQ + + IL L+ + + D ++R+F
Sbjct: 738 SQLQSQF---RLTYTMILNLLRV----DALRVEDMMKRSF 770
>gi|5902086 superkiller viralicidic activity 2 (S. cerevisiae homolog)-like;
170A [Homo sapiens] >gi|1403336|emb|CAA67024.1| (X98378)
SKI2W protein [Homo sapiens]
Length = 1246
Score = 120 bits (299), Expect = 4e-26
Identities = 120/460 (26%), Positives = 202/460 (43%), Gaps = 73/460 (15%)
Query: 40 ENLLVAIPTASGKTLIAEIAIANKLLEEGGKAVYIVPLKALAEEKFREFKDWERLGLKVA 99
+++ VA T++GKT++AE AIA + + +Y P+KAL+ +KFR+F++ G V
Sbjct: 326 DSVFVAAHTSAGKTVVAEYAIA-LAQKHMTRTIYTSPIKALSNQKFRDFRN--TFG-DVG 381
Query: 100 MATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSSWIRDVKMLVIDEIHLIGSRDRGATL 159
+ TGD E +I T E S+L GS IRD++ ++ DE+H I +RG
Sbjct: 382 LLTGDVQLHPE----ASCLIMTTEILRSMLYSGSDVIRDLEWVIFDEVHYINDVERGVVW 437
Query: 160 EFIITQMLGRAQIIGLSATIGNPEELAEWL------NAKLIRSDWRPVKLR--------- 204
E ++ + II LSAT+ N E A+W+ +I + RPV L
Sbjct: 438 EEVLIMLPDHVSIILLSATVPNALEFADWIGRLKRRQIYVISTVTRPVPLEHYLFTGNSS 497
Query: 205 ------------KGVFY-QGFVFWEDGGSERYNSWEELV---------YDAVKKGKGALV 242
+G F+ +G+ + ER + + A +G +
Sbjct: 498 KTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHAQTFGAKQPTHQGGPAQDRGVYLSL 557
Query: 243 FVNMRRKAE-------------------KTALEL-AKKVKNYLDRKELRELRELAESLEE 282
++R +A+ T+L+L K+ + R L L S +
Sbjct: 558 LASLRTRAQLPVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARLRGSDRQ 617
Query: 283 NPTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVI 342
P +++ L G+ HH+G+ + +VE F +GL+KV+ AT T + G+N PA V+
Sbjct: 618 LPQVLHMSELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNMPARTVV 677
Query: 343 IRDTWRYSEFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLV-IDHYIKGKP 401
++ + E QM GRAGR D G I++ P + + + GKP
Sbjct: 678 FDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMADLHRMMMGKP 737
Query: 402 EKLFSQLSNESILRSQILALIATFGYSEFKEIYDFLERTF 441
+L SQ + + IL L+ + + D ++R+F
Sbjct: 738 SQLQSQF---RLTYTMILNLLRV----DALRVEDMMKRSF 770
>emb|CAB88936.1| (AL353863) putative helicase [Streptomyces coelicolor A3(2)]
Length = 854
Score = 120 bits (299), Expect = 4e-26
Identities = 128/452 (28%), Positives = 204/452 (44%), Gaps = 56/452 (12%)
Query: 17 RERGIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLEEGGKAVYIVP 76
+ERG+ LYP Q EAL V+ G N++V+ PT SGK++IA A L + Y P
Sbjct: 42 QERGLT-LYPHQEEALIE-VVSGANVIVSTPTGSGKSMIAAGAHFAALARDE-VTFYTAP 98
Query: 77 LKALAEEKFREFKDWERLGLK-VAMATGDYDSKDEWLGKYDIIIATAEKFDSL-LRHGSS 134
+KAL EKF F+ + G + V M TGD + +I TAE S+ LR G
Sbjct: 99 IKALVSEKF--FELCKIFGTENVGMLTGDASVNSD----APVICCTAEVLASIALRDGKH 152
Query: 135 WIRDVKMLVIDEIHLIGSRDRGATLEFIITQMLGRAQIIGLSATIGN----PEELAEWLN 190
D+ +V+DE H DRG + + + L +AQ + +SAT+G+ ++LA +
Sbjct: 153 --ADIGQVVMDEFHFYAEPDRGWAWQIPLLE-LPQAQFVLMSATLGDVSFFEKDLARRTD 209
Query: 191 --AKLIRSDWRPVKLRKGVFYQGFVFWEDGGSERYNSWEELVYDAVKKGKGALVFVNMRR 248
++RS RPV L + F RY E + D + + + V+
Sbjct: 210 RPTAVVRSATRPVPL-------SYEF-------RYTPLTETLTDLLAARQAPVYIVHF-- 253
Query: 249 KAEKTALELAKKVK--NYLDRKELRELRELAESLE-ENPTNEKLAKALLSGVAFHHAGLG 305
+ A+E A+ + N R+E + + EL + L++ + G+ HHAG+
Sbjct: 254 -TQAQAVERAQALMSINMCTREEKQRIAELIGNFRFTTKFGRNLSRYVRHGIGVHHAGML 312
Query: 306 RDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWRYSEFGMERIPVLEVQQM 365
R LVE + GL+KV+ T TL G+N P V+ +Y + + E Q+
Sbjct: 313 PKYRRLVEKLAQAGLLKVICGTDTLGVGVNVPIRTVLFTALTKYDGTRVRTLRAREFHQI 372
Query: 366 MGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKGKPEKLFSQLSNESILRSQILALIATF 425
GRAGR +D G + + P V+++ EK ++ ++ R +++ A
Sbjct: 373 AGRAGRAGFDTEGFVV----AQAPEHVVEN------EKALAKAGDDPKKRRKVVRKKAPE 422
Query: 426 GYSEFKEIYDFLERTFYAHQGKDPYMLEEKIR 457
G+ + E TF G P L + R
Sbjct: 423 GFVAWS------ESTFDKLIGSQPEPLTSRFR 448
>sp|Q15477|SKIW_HUMAN HELICASE SKI2W (HELICASE-LIKE PROTEIN) (HLP)
Length = 1246
Score = 120 bits (299), Expect = 4e-26
Identities = 120/460 (26%), Positives = 202/460 (43%), Gaps = 73/460 (15%)
Query: 40 ENLLVAIPTASGKTLIAEIAIANKLLEEGGKAVYIVPLKALAEEKFREFKDWERLGLKVA 99
+++ VA T++GKT++AE AIA + + +Y P+KAL+ +KFR+F++ G V
Sbjct: 326 DSVFVAAHTSAGKTVVAEYAIA-LAQKHMTRTIYTSPIKALSNQKFRDFRN--TFG-DVG 381
Query: 100 MATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSSWIRDVKMLVIDEIHLIGSRDRGATL 159
+ TGD E +I T E S+L GS IRD++ ++ DE+H I +RG
Sbjct: 382 LLTGDVQLHPE----ASCLIMTTEILRSMLYSGSDVIRDLEWVIFDEVHYINDVERGVVW 437
Query: 160 EFIITQMLGRAQIIGLSATIGNPEELAEWL------NAKLIRSDWRPVKLR--------- 204
E ++ + II LSAT+ N E A+W+ +I + RPV L
Sbjct: 438 EEVLIMLPDHVSIILLSATVPNALEFADWIGRLKRRQIYVISTVTRPVPLEHYLFTGNSS 497
Query: 205 ------------KGVFY-QGFVFWEDGGSERYNSWEELV---------YDAVKKGKGALV 242
+G F+ +G+ + ER + + A +G +
Sbjct: 498 KTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHAQTFGAKQPTHQGGPAQDRGVYLSL 557
Query: 243 FVNMRRKAE-------------------KTALEL-AKKVKNYLDRKELRELRELAESLEE 282
++R +A+ T+L+L K+ + R L L S +
Sbjct: 558 LASLRTRAQLPVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARLRGSDRQ 617
Query: 283 NPTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVI 342
P +++ L G+ HH+G+ + +VE F +GL+KV+ AT T + G+N PA V+
Sbjct: 618 LPQVLHMSELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNMPARTVV 677
Query: 343 IRDTWRYSEFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLV-IDHYIKGKP 401
++ + E QM GRAGR D G I++ P + + + GKP
Sbjct: 678 FDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMADLHRMMMGKP 737
Query: 402 EKLFSQLSNESILRSQILALIATFGYSEFKEIYDFLERTF 441
+L SQ + + IL L+ + + D ++R+F
Sbjct: 738 SQLQSQF---RLTYTMILNLLRV----DALRVEDMMKRSF 770
>gb|AAC78607.1| (AF059675) putative RNA helicase Ski2w [Homo sapiens]
Length = 1246
Score = 120 bits (299), Expect = 4e-26
Identities = 120/460 (26%), Positives = 202/460 (43%), Gaps = 73/460 (15%)
Query: 40 ENLLVAIPTASGKTLIAEIAIANKLLEEGGKAVYIVPLKALAEEKFREFKDWERLGLKVA 99
+++ VA T++GKT++AE AIA + + +Y P+KAL+ +KFR+F++ G V
Sbjct: 326 DSVFVAAHTSAGKTVVAEYAIA-LAQKHMTRTIYTSPIKALSNQKFRDFRN--TFG-DVG 381
Query: 100 MATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSSWIRDVKMLVIDEIHLIGSRDRGATL 159
+ TGD E +I T E S+L GS IRD++ ++ DE+H I +RG
Sbjct: 382 LLTGDVQLHPE----ASCLIMTTEILRSMLYSGSDVIRDLEWVIFDEVHYINDVERGVVW 437
Query: 160 EFIITQMLGRAQIIGLSATIGNPEELAEWL------NAKLIRSDWRPVKLR--------- 204
E ++ + II LSAT+ N E A+W+ +I + RPV L
Sbjct: 438 EEVLIMLPDHVSIILLSATVPNALEFADWIGRLKRRQIYVISTVTRPVPLEHYLFTGNSS 497
Query: 205 ------------KGVFY-QGFVFWEDGGSERYNSWEELV---------YDAVKKGKGALV 242
+G F+ +G+ + ER + + A +G +
Sbjct: 498 KTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHAQTFGAKQPTHQGGPAQDRGVYLSL 557
Query: 243 FVNMRRKAE-------------------KTALEL-AKKVKNYLDRKELRELRELAESLEE 282
++R +A+ T+L+L K+ + R L L S +
Sbjct: 558 LASLRTRAQLPVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARLRGSDRQ 617
Query: 283 NPTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVI 342
P +++ L G+ HH+G+ + +VE F +GL+KV+ AT T + G+N PA V+
Sbjct: 618 LPQVLHMSELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNMPARTVV 677
Query: 343 IRDTWRYSEFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLV-IDHYIKGKP 401
++ + E QM GRAGR D G I++ P + + + GKP
Sbjct: 678 FDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMADLHRMMMGKP 737
Query: 402 EKLFSQLSNESILRSQILALIATFGYSEFKEIYDFLERTF 441
+L SQ + + IL L+ + + D ++R+F
Sbjct: 738 SQLQSQF---RLTYTMILNLLRV----DALRVEDMMKRSF 770
>emb|CAB89307.1| (AL049547) dJ34F7.7 (superkiller viralicidic activity 2 (S.
cerevisiae homolog)-like (SKI2W)) [Homo sapiens]
Length = 1245
Score = 120 bits (299), Expect = 4e-26
Identities = 120/460 (26%), Positives = 202/460 (43%), Gaps = 73/460 (15%)
Query: 40 ENLLVAIPTASGKTLIAEIAIANKLLEEGGKAVYIVPLKALAEEKFREFKDWERLGLKVA 99
+++ VA T++GKT++AE AIA + + +Y P+KAL+ +KFR+F++ G V
Sbjct: 325 DSVFVAAHTSAGKTVVAEYAIA-LAQKHMTRTIYTSPIKALSNQKFRDFRN--TFG-DVG 380
Query: 100 MATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSSWIRDVKMLVIDEIHLIGSRDRGATL 159
+ TGD E +I T E S+L GS IRD++ ++ DE+H I +RG
Sbjct: 381 LLTGDVQLHPE----ASCLIMTTEILRSMLYSGSDVIRDLEWVIFDEVHYINDVERGVVW 436
Query: 160 EFIITQMLGRAQIIGLSATIGNPEELAEWL------NAKLIRSDWRPVKLR--------- 204
E ++ + II LSAT+ N E A+W+ +I + RPV L
Sbjct: 437 EEVLIMLPDHVSIILLSATVPNALEFADWIGRLKRRQIYVISTVTRPVPLEHYLFTGNSS 496
Query: 205 ------------KGVFY-QGFVFWEDGGSERYNSWEELV---------YDAVKKGKGALV 242
+G F+ +G+ + ER + + A +G +
Sbjct: 497 KTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHAQTFGAKQPTHQGGPAQDRGVYLSL 556
Query: 243 FVNMRRKAE-------------------KTALEL-AKKVKNYLDRKELRELRELAESLEE 282
++R +A+ T+L+L K+ + R L L S +
Sbjct: 557 LASLRTRAQLPVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARLRGSDRQ 616
Query: 283 NPTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVI 342
P +++ L G+ HH+G+ + +VE F +GL+KV+ AT T + G+N PA V+
Sbjct: 617 LPQVLHMSELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNMPARTVV 676
Query: 343 IRDTWRYSEFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLV-IDHYIKGKP 401
++ + E QM GRAGR D G I++ P + + + GKP
Sbjct: 677 FDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMADLHRMMMGKP 736
Query: 402 EKLFSQLSNESILRSQILALIATFGYSEFKEIYDFLERTF 441
+L SQ + + IL L+ + + D ++R+F
Sbjct: 737 SQLQSQF---RLTYTMILNLLRV----DALRVEDMMKRSF 769
>gb|AAB52523.1| (U09877) helicase-like protein [Homo sapiens]
Length = 1245
Score = 120 bits (298), Expect = 5e-26
Identities = 120/460 (26%), Positives = 201/460 (43%), Gaps = 73/460 (15%)
Query: 40 ENLLVAIPTASGKTLIAEIAIANKLLEEGGKAVYIVPLKALAEEKFREFKDWERLGLKVA 99
+++ VA T++GKT++AE AIA + + +Y P+KAL +KFR+F++ G V
Sbjct: 325 DSVFVAAHTSAGKTVVAEYAIA-LAQKHMTRTIYTSPIKALTNQKFRDFRN--TFG-DVG 380
Query: 100 MATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSSWIRDVKMLVIDEIHLIGSRDRGATL 159
+ TGD E +I T E S+L GS IRD++ ++ DE+H I +RG
Sbjct: 381 LLTGDVQLHPE----ASCLIMTTEILRSMLYSGSDVIRDLEWVIFDEVHYINDVERGVVW 436
Query: 160 EFIITQMLGRAQIIGLSATIGNPEELAEWL------NAKLIRSDWRPVKLR--------- 204
E ++ + II LSAT+ N E A+W+ +I + RPV L
Sbjct: 437 EEVLIMLPDHVSIILLSATVPNALEFADWIGRLKRRQIYVISTVTRPVPLEHYLFTGNSS 496
Query: 205 ------------KGVFY-QGFVFWEDGGSERYNSWEELV---------YDAVKKGKGALV 242
+G F+ +G+ + ER + + A +G +
Sbjct: 497 KTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHAQTFGAKQPTHQGGPAQDRGVYLSL 556
Query: 243 FVNMRRKAE-------------------KTALEL-AKKVKNYLDRKELRELRELAESLEE 282
++R +A+ T+L+L K+ + R L L S +
Sbjct: 557 LASLRTRAQLPVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARLRGSDRQ 616
Query: 283 NPTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVI 342
P +++ L G+ HH+G+ + +VE F +GL+KV+ AT T + G+N PA V+
Sbjct: 617 LPQVLHMSELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNMPARTVV 676
Query: 343 IRDTWRYSEFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLV-IDHYIKGKP 401
++ + E QM GRAGR D G I++ P + + + GKP
Sbjct: 677 FDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMADLHRMMMGKP 736
Query: 402 EKLFSQLSNESILRSQILALIATFGYSEFKEIYDFLERTF 441
+L SQ + + IL L+ + + D ++R+F
Sbjct: 737 SQLQSQF---RLTYTMILNLLRV----DALRVEDMMKRSF 769
>pir||B75127 large helicase-related protein (lhr-1) PAB1817 - Pyrococcus abyssi
(strain Orsay) >gi|5458242|emb|CAB49731.1| (AJ248285)
large helicase-related protein (lhr-1) [Pyrococcus
abyssi]
Length = 912
Score = 117 bits (290), Expect = 5e-25
Identities = 135/513 (26%), Positives = 224/513 (43%), Gaps = 90/513 (17%)
Query: 12 IKEILRERGIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLEEG--- 68
+K+ ++E+ EL Q EA + EG+++L+ PT SGKT A + + N +L++G
Sbjct: 5 LKKAIKEK-FRELNRLQIEAFKR-ISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPP 62
Query: 69 GKAVYIVPLKALAEEKFREFKDWE-RLGLKVAMATGD---YDSKDEWLGKYDIIIATAEK 124
+YI PLKAL + K WE + G+++ + GD Y + ++I T E
Sbjct: 63 ISCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPET 122
Query: 125 FDSLLRHGS--SWIRDVKMLVIDEIHLIGSRDRGATLEFIITQMLGRAQI--IGLSATIG 180
+LL S ++++V+ +V+DE+ + RGA L + ++ A IGLSAT+G
Sbjct: 123 LPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVG 182
Query: 181 NPEELAEWLNAKLIRSDWRPVKLRKGVFYQGFVFWEDGGSERYNSWEEL----------- 229
N EE+ EWL I P+K R Y+ V + E E L
Sbjct: 183 NEEEVKEWLGVDEIVKP--PLKKR----YKFKVLFPRPRPEDKELAELLRVDVEVAARLR 236
Query: 230 -VYDAVKKGKGALVFVNMRRKAEKTALELAKKVKNYLDRKELRELRELAESLEENPTNEK 288
+++ V+K K LVFVN R+ AE A L
Sbjct: 237 TLWEIVEKHKRVLVFVNTRQFAEVLAHRL------------------------------- 265
Query: 289 LAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWR 348
K V HH L ++ R+ E ++G +K ++ T ++ GI+ +I
Sbjct: 266 --KTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALICTSSMELGIDIGEVDAVI----- 318
Query: 349 YSEFGMERIPVLEVQQMMGRAGRPRYD--EVGEAIIVSTTEEPSL----VIDHYIKGKPE 402
+ + +V +++ RAGR ++ EV EA I++T E L + I+GK E
Sbjct: 319 ------QYMSPRQVNRLIQRAGRSKHRLLEVSEAYIIATGVEDYLQSLIIAKRAIEGKLE 372
Query: 403 KLFSQLSNESILRSQILALIATFGYSEFKEIYDFLERTFYAHQGKDPYMLEEKIRRIIYF 462
++ + +L I+ L+ + E Y + T+ K + LE +
Sbjct: 373 RIKPYENALDVLAHFIVGLLIEYQKLNVHEPYRMAKETYPYRNLKWEHYLE------VIN 426
Query: 463 LLENEFIEVTLEDEIKPLPLGVRTTKLYIDPMT 495
+LE+ I + E+ I L LG R K Y D ++
Sbjct: 427 VLEDAGI-IRREEGI--LKLGRRAFKYYFDNLS 456
>pir||C71004 probable ATP-dependent helicase - Pyrococcus horikoshii
>gi|3257752|dbj|BAA30435.1| (AP000006) 912aa long
hypothetical ATP-dependent helicase [Pyrococcus
horikoshii]
Length = 912
Score = 116 bits (289), Expect = 6e-25
Identities = 133/515 (25%), Positives = 223/515 (42%), Gaps = 93/515 (18%)
Query: 12 IKEILRERGIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLEEGGKA 71
+K+ ++E+ +L Q +A + EGE++L+ PT SGKT A I + N +L++ +
Sbjct: 5 LKKAIKEK-FGKLNKLQIQAFKAIYGEGESVLIIAPTGSGKTEAAIIPVINSILKDNLRP 63
Query: 72 V---YIVPLKALAEEKFREFKDW-ERLGLKVAMATGDYDSK---DEWLGKYDIIIATAEK 124
+ YI PLKAL + K W E+ G+KV + GD + I+I T E
Sbjct: 64 ISCLYIAPLKALNRDLLERLKWWGEKTGIKVEVRHGDTPQSMRAKQVKNPPHILITTPES 123
Query: 125 FDSLLRHGS--SWIRDVKMLVIDEIHLIGSRDRGATLEFIITQMLGRAQII--GLSATIG 180
++L S ++ +VK +++DEI + RG L + ++ A I GLSAT+G
Sbjct: 124 LPAILTTKSLRKYLENVKFVIVDEITELVDNKRGIQLILNLKRLSLIADFIRIGLSATVG 183
Query: 181 NPEELAEWLNAKLIRSDWRPVKLRKGVFYQGFVFWEDGGSERYNSWEEL----------- 229
N EE+ EW AK R +K Y+ V + E E+L
Sbjct: 184 NEEEIREWFEAK------RIIKPHLKKRYKFKVLYPQPKPEDQELAEKLKVPGDVATRLR 237
Query: 230 -VYDAVKKGKGALVFVNMRRKAEKTALELAKKVKNYLDRKELRELRELAESLEENPTNEK 288
+++ V+K K AL+FVN R+ AE L
Sbjct: 238 TLWEIVEKYKKALIFVNTRQFAEILGHRL------------------------------- 266
Query: 289 LAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWR 348
K V HH L ++ R+ E ++G IK ++ T ++ GI+ V+I
Sbjct: 267 --KTWGKPVEVHHGSLSKEARIEAERKLKEGKIKALICTSSMELGIDIGDVDVVI----- 319
Query: 349 YSEFGMERIPVLEVQQMMGRAGRPRYD--EVGEAIIVSTTEEPSL----VIDHYIKGKPE 402
+ + +V +++ RAGR R+ EV EA I++T E L + ++GK E
Sbjct: 320 ------QYMSPRQVNRLIQRAGRSRHRLWEVSEAYIITTGVEDYLQGLVIAKRALEGKLE 373
Query: 403 KLFSQLSNESILRSQILALIATFGYSEFKEIYDFLERTFYAHQGKDPY--MLEEKIRRII 460
+ + +L I+ L+ + + E Y + T+ PY + E R++
Sbjct: 374 GVKPYENALDVLAHFIVGLLIEYRDLKINEPYRLAKDTY-------PYRKLRWEDYLRVL 426
Query: 461 YFLLENEFIEVTLEDEIKPLPLGVRTTKLYIDPMT 495
L E I+ ED ++ LG ++ K Y + ++
Sbjct: 427 EILEEAGIIK-RHEDRLR---LGRKSFKYYFENLS 457
>pir||T34471 hypothetical protein W03A3.3 - Caenorhabditis elegans
>gi|1226250|gb|AAB93324.1| (U50184) short region of
similarity to S. cerevisiae antiviral protein SKI2
(SP:P35207) [Caenorhabditis elegans]
Length = 273
Score = 116 bits (288), Expect = 8e-25
Identities = 83/254 (32%), Positives = 138/254 (53%), Gaps = 28/254 (11%)
Query: 141 MLVIDEIHLIGSRDRGATLEFIITQML-------GRAQIIGLSATIGNPEELAEWLN-AK 192
M+V+DE+H++ RGA +E +++++L + +IIG+SATI + +WL+ AK
Sbjct: 1 MIVVDEMHMVFDSSRGAHIEHMLSKVLLWNQSALEKVRIIGMSATIPELYRIGKWLDGAK 60
Query: 193 LIRSDWRPVKLRKGVFYQGFVFWEDGGSERYNSWEE-----LVYDAVKKGKGALVFVNMR 247
+ + +RP+ L+ + G + G ++ + E L ++ ++ LV ++ +
Sbjct: 61 VFEARFRPIVLQNHIVI-GSELRKSGDNKVLREFSEDPLILLTEESFRRNSQTLVMISSK 119
Query: 248 RKAEKTALELAKKVK--NYLDRKELRELRELAESL-------EENPTNEKLAKALLS-GV 297
AEKTAL +A + N D L L+E A L E N ++ + L+ GV
Sbjct: 120 LDAEKTALNIASRFHEINKTDSSLLEILKERANGLLFIKHGLERNGCKDRNVMSTLAWGV 179
Query: 298 AFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWRYSEFGMERI 357
A+HHAGL +ER +E FR+ I ++VAT TL++G+N PA RV+I+ R G +
Sbjct: 180 AYHHAGLTMEERECIELGFREKNIVILVATSTLASGVNLPAERVLIKAQPR----GPSAL 235
Query: 358 PVLEVQQMMGRAGR 371
L +QM+GRAGR
Sbjct: 236 TSLNYRQMVGRAGR 249
>gb|AAF59592.1| (AC024820) contains similarity to TR:O18475 [Caenorhabditis
elegans]
Length = 563
Score = 115 bits (285), Expect = 2e-24
Identities = 93/337 (27%), Positives = 172/337 (50%), Gaps = 33/337 (9%)
Query: 10 EKIKEILRE-RGIEELYPPQAEALTSG-VLEGENLLVAIPTASGKTLIAEIAIANKLLEE 67
E+ E+ R+ + +++ Y Q E L+ +L+GEN ++++PT +GKTLIAE+ + + +
Sbjct: 185 ERDMEMYRKIKKLDKFYDWQQECLSDKRLLDGENCILSLPTGAGKTLIAEVLMLREAIVR 244
Query: 68 GGKAVYIVPLKALAEEK---FREFKDWERLGLKVAMATGDYDSKDEWLGKYDIIIATAEK 124
A+ ++P A+ +EK F+D + ++ + + + + +AT EK
Sbjct: 245 KRNAILVLPYVAIVQEKISALAPFEDAFGINIEEYASNKGRFPPIKRRKRVSVYVATIEK 304
Query: 125 ----FDSLLRHGSSWIRDVKMLVIDEIHLIGSRDRGATLEFIITQML--GRAQIIGLSAT 178
+SL+ G + V M+V+DE+H+IG RGA LE ++ + L G QI+G+SAT
Sbjct: 305 ANMLINSLITQGQ--LDRVGMVVVDELHMIGDGGRGAILEQLLAKFLYKGTGQIVGMSAT 362
Query: 179 IGNPEELAEWLNAKLIRSDWRPVKLRKGVFYQGFVFWEDGGSERYNSWEELVYDAVKK-- 236
+ N ++L L A + +++RPV+L + V G + + N +L + +K
Sbjct: 363 LPNIDDLKFALRAFVYSTNFRPVELTEFVKI-GQTMHQVSENGDLNPAGDLPTNNLKSTD 421
Query: 237 -------------GKGALVFVNMRRKAEKTALELAKKVKNYLDRKELRELRELAESLEEN 283
A++F ++ E A+ +AK + ++ + + E +S +
Sbjct: 422 PDGICQLLAKLIPKNSAVIFCPNKKNCENVAVLIAKTLPAHIRQAKRAESDAFLQSYLSD 481
Query: 284 PTNEK----LAKALLSGVAFHHAGLGRDERVLVEDNF 316
+E+ L + +LSGVA+HH+GL +DER VE F
Sbjct: 482 NDDERMDAVLKQCILSGVAYHHSGLTQDERKCVEAAF 518
>gb|AAF24214.1|AF165818_7 (AF165818) putative helicase-like protein [Guillardia theta]
Length = 719
Score = 115 bits (285), Expect = 2e-24
Identities = 104/379 (27%), Positives = 177/379 (46%), Gaps = 54/379 (14%)
Query: 41 NLLVAIPTASGKTLIAEIAIANKLLEEGGKAVYIVPLKALAEEKFREFKDWERLGLKVAM 100
++ VA T+SGKTL+ E I + L + + +Y+ P+KAL+ +KF +FK+ + V +
Sbjct: 72 DIFVAAHTSSGKTLVGEQVIFSTL-KLNKRVIYLSPIKALSNQKFEDFKN---IFYNVGI 127
Query: 101 ATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSSWIRDVKMLVIDEIHLIGSRDRGATLE 160
TGD + + +I T E F + + S+W++++ ++IDE H I RG E
Sbjct: 128 ITGDQIINPD----ANCVIMTTEIFRLYILNNSNWLKNINYIIIDEAHFIFDETRGFVWE 183
Query: 161 FIITQMLGRAQIIGLSATIGNPEELAEWL---NAKL---IRSDWRPVKLRKGVFY----- 209
II G II LSATI N E++EW+ K+ I++D R + L ++
Sbjct: 184 EIIIITPGYINIIYLSATISNLMEMSEWIFITRKKILFTIKTDRRIIPLVNYIYLSKIDK 243
Query: 210 ----------QGFVFWEDGGSE---RYNSWEE---------------LVYDAVKKGKGAL 241
+ +F G + R NS ++ L+Y K K L
Sbjct: 244 IAKLDFFLKNKNLIFNYKKGIKINFRKNSIQDFNQLIRLLKNKNLLPLIYFIFNKKKCIL 303
Query: 242 VFVNMRRKAEKTALELAKKVKNYLDR--KELRELRELAESLEENPTNEKLAKALLSGVAF 299
+ N + + + E KN L+R + + + ++ + E + + LL+G+A
Sbjct: 304 LSKNFMKFSFLSIFE-----KNILNRLLEMIGKKKKFSIISHELDSYKNFWILLLNGIAV 358
Query: 300 HHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWRYSEFGMERIPV 359
H++ + + L+E F+ LIK++ AT T S G+N PA V+ ++ + ++
Sbjct: 359 HNSDISIVSKKLIEILFQVNLIKILFATETFSIGLNMPAKTVVFHTLKKFDGNKIRKLRK 418
Query: 360 LEVQQMMGRAGRPRYDEVG 378
E QM GRAGR D G
Sbjct: 419 SEFIQMSGRAGRRGIDHKG 437
>gi|11499982 ATP-dependent RNA helicase, putative [Archaeoglobus fulgidus]
>gi|7446072|pir||G69550 ATP-dependent RNA helicase
homolog AF2406 - Archaeoglobus fulgidus
>gi|2650686|gb|AAB91259.1| (AE001109) ATP-dependent RNA
helicase, putative [Archaeoglobus fulgidus]
Length = 766
Score = 110 bits (273), Expect = 5e-23
Identities = 114/429 (26%), Positives = 195/429 (44%), Gaps = 79/429 (18%)
Query: 11 KIKEILRERGIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLEEGGK 70
++ LR+RGI LYP Q EA+ ++EG ++++ PT GKT + + + L GGK
Sbjct: 73 ELASCLRKRGIGRLYPFQKEAMIR-LMEGRDVVITAPTGFGKTEAFAVPMLWRAL-HGGK 130
Query: 71 AVYIVPLKALAEEKFREFKDW-ERLGLKVAMATGDYDSKDE---WLGKYDIIIATAEKFD 126
A+ P KALA ++ + K + LGL+ GD ++ GK DII+ + D
Sbjct: 131 AMVFYPTKALARDQEEKIKFYTSSLGLRAVRFDGDSGREERRAVLSGKCDIILTNPDMVD 190
Query: 127 SLLRHGSSW---IRDVKMLVIDEIHLIGSRDRGATLEFIITQM--LGRAQIIGLSATIGN 181
LR+ ++ R++ + +DE+H + G+ + +++ ++ QI SAT+ N
Sbjct: 191 YHLRNTPAFRRICRELSFIAVDELHTY-TGVLGSNMHYLVKRLSRFAEFQIACASATLSN 249
Query: 182 PEELAEWLNAKLIRSDWRPV--KLRKGVFYQGFVFWEDGGSERYNSWEELVYDAVKKGKG 239
E AE +L D+ V + RKG + F + Y++ E+V + +
Sbjct: 250 AAEFAE----ELFDRDFVLVSGEHRKGTLHLIFRY----TPSLYSAVREIV--TALRNRK 299
Query: 240 ALVFVNMRRKAEKTALELAKKVKNYLDRKELRELRELAESLEENPTNEKLAKALLSGVAF 299
+VF N + E L L R L+ A
Sbjct: 300 IIVFGNSYKSVETINL--------ILRRHGLKS-------------------------AI 326
Query: 300 HHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWRYSEFGMERIPV 359
H +GL ++ R VE F++G I +VV+TPTL G++ V++ E +P
Sbjct: 327 HKSGLPKEVREEVEAKFKRGEINIVVSTPTLELGVDIGDVDVVV----------SELVPY 376
Query: 360 LEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKGKPEKLFSQLS-------NES 412
++ Q +GRAGR + VG +V E+ S I Y + KPE F + + NE
Sbjct: 377 GQMIQRVGRAGRKGQESVG---VVILREDDS--ISTYYRTKPEDYFKEEANGYVERHNEE 431
Query: 413 ILRSQILAL 421
+++ Q++++
Sbjct: 432 VMKFQLISM 440
>sp|P50830|YPRA_BACSU HYPOTHETICAL HELICASE IN PONA-COTD INTERGENIC REGION
>gi|7446091|pir||B69941 ATP-dependent RNA helicase
homolog yprA - Bacillus subtilis
>gi|1146178|gb|AAB38468.1| (L47838) helicase [Bacillus
subtilis] >gi|2634641|emb|CAB14139.1| (Z99115) similar
to ATP-dependent helicase [Bacillus subtilis]
Length = 749
Score = 110 bits (273), Expect = 5e-23
Identities = 124/481 (25%), Positives = 200/481 (40%), Gaps = 79/481 (16%)
Query: 7 NVSEKIKEILRERGIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLL- 65
++ E+IK L +RGI+ELY Q A V +GE+++ PTASGKTL + + +
Sbjct: 38 SIDERIKAALSKRGIDELYTHQYSAFQY-VQKGESIVTVTPTASGKTLCYNLPVLQSIAQ 96
Query: 66 EEGGKAVYIVPLKALAEEKFREFKD-WERLGLKVAMATGDYDSKDEWLGKY----DIIIA 120
+E +A+Y+ P KALA+++ E + + +G+ + T D D+ K I+I
Sbjct: 97 DETNRALYLFPTKALAQDQKSELNEIIDEMGIDIKSFTYDGDTSPAIRQKVRKAGHIVIT 156
Query: 121 TAEKFDS-LLRHGSSWI---RDVKMLVIDEIH----LIGSRDRGATLEF-IITQMLGRAQ 171
+ S +L H + W+ ++K +VIDE+H + GS I + G
Sbjct: 157 NPDMLHSAILPHHTKWVSLFENLKYIVIDELHTYRGVFGSHVANVIRRLKRICRFYGSDP 216
Query: 172 I-IGLSATIGNPEELAEWLNAK---LIRSDWRPVKLRKGVFYQGFVFWEDGGSERYNSWE 227
+ I SATI NP+EL E L K L+ + P + VFY + + R + E
Sbjct: 217 VFICTSATIANPKELGEQLTGKPMRLVDDNGAPSGRKHFVFYNPPIVNKPLNIRRSATAE 276
Query: 228 --ELVYDAVKKGKGALVFVNMRRKAEKTALELAKKVKNYLDRKELRELRELAESLEENPT 285
EL + +K +VF R + E + + VK + K +R R
Sbjct: 277 VNELAKEFLKNKVQTIVFARSRVRVEIILSHIQELVKKEIGTKSIRGYR----------- 325
Query: 286 NEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRD 345
G ER +E R+G I VV+T L G++ +V +
Sbjct: 326 ----------------GGYLPKERREIERGLREGDILGVVSTNALELGVDIGQLQVCVMT 369
Query: 346 TWRYSEFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKGKPEKLF 405
+ S V Q GRAGR GE++I+ S ID YI PE F
Sbjct: 370 GYPGS--------VASAWQQAGRAGRRH----GESLIIMVAN--STPIDQYIVRHPEYFF 415
Query: 406 SQLSNESILRSQILALIA----------------TFGYSEFKEIYDFLERTFYAHQGKDP 449
++ + + + L ++ FG E +I ++L+ H+ +
Sbjct: 416 NRSPESARINPENLIILVDHLKCAAYELPFRADEEFGAMEVSDILEYLQEEAVLHRNGER 475
Query: 450 Y 450
Y
Sbjct: 476 Y 476
>emb|CAB58415.1| (AL122012) possible MUS308 homolog [Leishmania major]
Length = 2207
Score = 109 bits (271), Expect = 8e-23
Identities = 127/496 (25%), Positives = 192/496 (38%), Gaps = 141/496 (28%)
Query: 19 RGIEELYPPQAEALTSG-VLEGENLLVAIPTASGKTLIAEIAIANKLLEEGGKAVYIVPL 77
RG+ LY Q + LT V +G N + ++PT+ GKTL+AE+++ +L ++P
Sbjct: 1225 RGVTSLYDWQHDVLTRPEVRQGGNFVYSLPTSGGKTLVAELSLLRCVLNRRKSCFLVLPF 1284
Query: 78 KALAEEKFREFKDWERLGLKVAM---ATGDYDSKDEW--LGKYDIIIATAEKFDSLLRHG 132
+LAEEK + L A G Y S + G + + T EK +SLL H
Sbjct: 1285 VSLAEEKTMALQP-----LTTAYDFNVDGHYGSSGRFPLSGAPAVYVCTIEKANSLLNHM 1339
Query: 133 SSWIR--DVKMLVIDEIHLIGSRDRGATLEFIITQML-------------------GRAQ 171
R ++ +V+DE+H++G RGATLE ++++L R
Sbjct: 1340 LEEGRTDEIGAVVVDELHMVGESGRGATLELFLSKVLVINAARQRKRDAVVAPATQSRCS 1399
Query: 172 IIGLSATIGNPEEL-----------------------------------------AEWLN 190
GL G PEEL AEWL
Sbjct: 1400 ASGLRP--GWPEELEDAEEDLHERAVMTDTAKAASDPGSLQIIGMSATVPNLRTLAEWLR 1457
Query: 191 AKLIRSDWRPVKLRKGVFYQGFVFWEDGGSERYNSWEELVYDAVK-----KGKGALVFVN 245
A D+RPV L G V + +ER S + + V+ L+F
Sbjct: 1458 AAYFEYDFRPVPLHAYSVVGGLVLRDGQHNERNLSSDSVTQHLVELATEVPDASVLIFCA 1517
Query: 246 MRRKAEKTALELAKKVKNYL-----------------------DRKELRELRELAESLEE 282
R++ ++ AK + NYL + + + L SL
Sbjct: 1518 SRQQ----CVDTAKGIVNYLKAQAIAGQKVPSPWMSGSSDAAAEAQHVSVLGVPFPSLTR 1573
Query: 283 NPTNEKL-------AKALLSG-------------------VAF----HHAGLGRDERVLV 312
P A A + G +AF HH GL +ER L+
Sbjct: 1574 GPVTAAAMAAVPPQASAAIKGLLADLEALAHHEASQLSEVIAFGVAFHHGGLLAEERDLI 1633
Query: 313 EDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWRYSEFGMERIPVLEVQQMMGRAGRP 372
E FR+ I+++ T TL+AG+N PA RVII+ + G E + QM GRAGR
Sbjct: 1634 ETAFRRKHIRILCCTSTLAAGVNLPARRVIIKTPY----VGREFLTKSRYLQMCGRAGRA 1689
Query: 373 RYDEVGEAIIVSTTEE 388
D GE+ ++ ++ +
Sbjct: 1690 GLDPYGESFLLLSSRD 1705
>pir||T17399 probable DEAH ATP-dependent helicase vrlS - Dichelobacter nodosus
>gi|924612|gb|AAC33388.1| (U20246) putative DEAH
ATP-dependent helicase [Dichelobacter nodosus]
Length = 1130
Score = 107 bits (264), Expect = 5e-22
Identities = 103/416 (24%), Positives = 173/416 (40%), Gaps = 79/416 (18%)
Query: 21 IEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLEEG-GKAVYIVPLKA 79
I+EL+P Q + VL+GE+ +V +PT++GKT E+ + + L E A+ I PL+
Sbjct: 241 IKELWPAQHLLGKADVLKGESAIVQMPTSAGKTKATELILRSAFLAERVSLAIIIAPLRT 300
Query: 80 LAEE--------------KFREFKDWERLGLKVAMATGDYDSKDEWLGKYDIIIATAEKF 125
L E K E D + ++A E LG I++ T EK
Sbjct: 301 LCHEIKNSLVEAFHNEPTKVDELSDALQTDFEIA----------ELLGHQQILVVTPEKL 350
Query: 126 DSLLRHGSSWIRDVKMLVIDEIHLIGSRDRGATLEFIITQMLGR----AQIIGLSATIGN 181
+LRH + +LV DE H S RG T E ++T + Q + +SA I N
Sbjct: 351 LYVLRHAPELAAHIGLLVFDEGHQFDSGTRGITYELLLTSLRSMIPAGTQKVLISAVISN 410
Query: 182 PEELAEWLNAK-------LIRSDWRPVKLRKGVFYQGFVFWEDGGS------------ER 222
E + EWLN + + +R V + G + + D ER
Sbjct: 411 AEAVGEWLNGEPNVVEGTTLIPTFRSVGFASWLDQLGRIEYVDSRDAEQGEFFVPRVIER 470
Query: 223 YN------SWEELVYDAVKKGKGALVFVNMRR----------KAEKTALELAKKVKNYLD 266
+N + + G+ +++ ++ + TA + +K + ++
Sbjct: 471 FNLGRKKRERTDRFFPEKTDGQAIALYLGLKLVPNGSIALFCGRKSTAASVCEKAVDIIE 530
Query: 267 R----------KELRELRELAESLEEN-PTNEKLAKALLSGVAFHHAGLGRDERVLVEDN 315
R + +E+ L EN + +++ G+ HH R++VE
Sbjct: 531 RGAPVVLPSDFSDAQEVERLTHLHVENLGADAPASQSEAHGIFSHHGNTPHGIRLVVEHA 590
Query: 316 FRKGLIKVVVATPTLSAGINTPAFRVIIRDTWRYSEFGMERIPVLEVQQMMGRAGR 371
R L++ VV T TL+ G+N P +I+ ++ GMERI V + ++GRAGR
Sbjct: 591 MRDDLVRFVVCTSTLAQGVNLPIRYLIVTSVYQ----GMERIKVRDFHNLIGRAGR 642
>pir||A69140 ATP-dependent helicase - Methanobacterium thermoautotrophicum
(strain Delta H) >gi|2621366|gb|AAB84818.1| (AE000816)
ATP-dependent helicase [Methanobacterium
thermoautotrophicum]
Length = 702
Score = 103 bits (254), Expect = 8e-21
Identities = 129/485 (26%), Positives = 200/485 (40%), Gaps = 81/485 (16%)
Query: 7 NVSEKIKEILRER-GIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLL 65
+++ +++ L R G L Q AL + + GE+ L+ PTASGKT A I + N +L
Sbjct: 5 SLNPRLRHFLANRLGWRSLRDVQKSALEA-IGRGEDTLIVAPTASGKTEAALIPVFNSIL 63
Query: 66 EEGGKAV---YIVPLKALAEEKFREFKDW-ERLGLKVAMATGDYDS--KDEWL-GKYDII 118
EG V Y+ PLKAL + + W L+V GD + K ++ DI+
Sbjct: 64 SEGLPPVSMLYVSPLKALINDMHSRLELWGNHFNLEVMKWHGDVPANRKRRFIKNPSDIL 123
Query: 119 IATAEKFDSLLRHGSSWIRD-----VKMLVIDEIHLIGSRDRGATLEFIITQMLG----R 169
+ T E + ++ + S ++ ++ +++DEIH DRG L ++ ++ R
Sbjct: 124 LITPESLEVMMINRSRAEKERILGNLRYIIVDEIHQFIEADRGVQLNSLLARLERYTGVR 183
Query: 170 AQIIGLSATIGNPEELAEWLN-AKLIRSDWRPVKLRKGVFYQGFVFWEDGGSERYNSWEE 228
Q IGLSAT+GNPEE+ W++ + + D KL+ +F N +
Sbjct: 184 PQRIGLSATVGNPEEVLNWMSPSGAVVRDTAERKLQYRIF-------------ELNHHKL 230
Query: 229 LVYDAVKKGKGALVFVNMRRKAEKTALELAKKVKNYLDRKELRELRELAESLEENPTNEK 288
+ GK L+FV RR AEK
Sbjct: 231 IEVLRRFTGKKVLIFVPSRRDAEK--------------------------------YYNI 258
Query: 289 LAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWR 348
+ K L V HH+ + RD R E+ FR +V T TL GI+ V+I
Sbjct: 259 IRKCLDVDVFIHHSSINRDSREEAEERFRSVSAAFMVNTSTLELGIDVGDIDVVIHIRSP 318
Query: 349 YSEFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSL--VIDHYIKGKPEKLFS 406
S V Q GR+GR R + II E + V + G+ E L
Sbjct: 319 TS--------VNRFLQRTGRSGRRR--GLQRTIIFQEKEALTALSVASLALSGRLEDLRI 368
Query: 407 QLSNESILRSQILALIATFGYSEFKEIYDFLERTFYAHQGKDPYMLEEKIRRIIYFLLEN 466
+ I QIL+ + +IY L R AH D + + R ++ F++EN
Sbjct: 369 PVRPLDIYFHQILSSVFELEKPTPGDIYRGLGR---AHVFSD--LDADDFRHLVEFMVEN 423
Query: 467 EFIEV 471
+F+ V
Sbjct: 424 DFLRV 428
>pir||S76892 hypothetical protein - Synechocystis sp. (strain PCC 6803)
>gi|1653894|dbj|BAA18804.1| (D90917) antiviral protein
[Synechocystis sp.]
Length = 1006
Score = 101 bits (250), Expect = 2e-20
Identities = 75/221 (33%), Positives = 114/221 (50%), Gaps = 47/221 (21%)
Query: 28 QAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLEEGGKAVYIVPLKALAEEKFRE 87
Q EA+ + + + ++++V PT SGKT++ E AI + + G + Y PLKAL+ +K R+
Sbjct: 21 QQEAIAA-LDQDQSVVVCAPTGSGKTVVGEYAIY-RAIARGKRVFYTTPLKALSNQKIRD 78
Query: 88 FKD-WERLGLK-----VAMATGDYDSKDEWLGKYDIIIATAEKFDSLLRH------GSSW 135
F++ E+LGL+ V + TGD + +++ T E F ++L G+S
Sbjct: 79 FQEKLEKLGLENAAQLVGLITGDTVINAD----APVVVMTTEIFRNMLYETPIGEVGTS- 133
Query: 136 IRDVKMLVIDEIHLIGSRDRGATLEFIITQMLGRAQIIGLSATIGNPEELAEWLN----- 190
+ DV+ +V DE+H I R RG E I Q++GLSATIGNPE+L EW+N
Sbjct: 134 LEDVETVVFDEVHYISDRGRGTVWEESIIYCPSTIQLVGLSATIGNPEQLTEWINQVRTG 193
Query: 191 -----------------AKLIRSDWRPVKL------RKGVF 208
L+ SD+RPV L RKG+F
Sbjct: 194 VSLKVLRQGEQRNDSPPCVLVNSDFRPVPLTFHYSTRKGLF 234
Score = 79.2 bits (192), Expect = 1e-13
Identities = 69/222 (31%), Positives = 98/222 (44%), Gaps = 23/222 (10%)
Query: 237 GKGALVFVNMRRKAEKTALELAKKVKNYLDRKELRELRE-LAESLEENP----------- 284
GK L+ + R +L + V YLD + E + L +L +P
Sbjct: 329 GKNPLLRQKLERDLANGLPDLVQAVVAYLDHPQDSEAAQRLLTALAIDPEGMFKLWGWIA 388
Query: 285 -----TNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAF 339
T + + LL G+A HHAG+ D + LVE F +GLIKVV AT TLSAGIN PA
Sbjct: 389 QSSPMTRFEQIEPLLRGIAVHHAGILPDMKTLVEKLFEQGLIKVVFATATLSAGINMPAR 448
Query: 340 RVIIRDTWRYSEFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKG 399
+I + + G + E Q+ GRAGR D G I V T E + +
Sbjct: 449 TTVISALSKRTNEGHAMLSPSEFLQIAGRAGRRGMDTEGHVITVQTPFEGANEASYLALA 508
Query: 400 KPEKLFSQLSNESILRSQILALIATFGYSEFKEIYDFLERTF 441
+ E L S + +L L+ + +E+ LER+F
Sbjct: 509 EAEPLKSWFTPS---YGMVLNLLQK---HDLEEVKSLLERSF 544
>gb|AAK40467.1| ATP-dependent helicase [Sulfolobus solfataricus]
Length = 875
Score = 101 bits (248), Expect = 4e-20
Identities = 110/393 (27%), Positives = 180/393 (44%), Gaps = 72/393 (18%)
Query: 26 PPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLEEGGK--------AVYIVPL 77
PPQ A+ + + N+LV+ PT SGKTL A + I + L E G A+YI PL
Sbjct: 33 PPQRAAIPL-IKQNYNVLVSSPTGSGKTLAAFLGILDSLFELGDNNELEDKVYAIYISPL 91
Query: 78 KALAEEKFREFKD-------------WERLGLKVAMATGDYDSKDEWLGKYDIIIATAEK 124
+AL + R + R+G++ + T Y+ + I+I T E
Sbjct: 92 RALNNDMQRNLLEPLNELRQVNSKLPDVRVGIRTSDTT-PYEKQKMLKKPPHILITTPES 150
Query: 125 FDSLLRHG--SSWIRDVKMLVIDEIHLIGSRDRGATLEFII---TQMLGRAQI--IGLSA 177
F + S + DVK +++DEIH + + RGA L ++ ++ + + IGLSA
Sbjct: 151 FGISITSPKFSQKLTDVKWIIVDEIHELANSKRGAYLSAMLELFRNLITKKEFVRIGLSA 210
Query: 178 TIGNPEELAEWLNAK-----LIRSDW-RPVKLRKGVFYQGFVFWEDGGSERYNSWEELVY 231
T+ EE+A++L K ++ + + +PV ++ + V SE + +
Sbjct: 211 TVSPLEEVAQFLVGKDREYRIVDARFVKPVDIKVISPVKDLV--HSSESEVDKGIYKTIL 268
Query: 232 DAVKKGKGALVFVNMRRKAEKTALELAKKVKNYLDRKELRELRELAESLEENPTNEKLAK 291
+ VKK + L+F N R E+ A +LR+LAE NEK+
Sbjct: 269 NEVKKHRTTLIFTNTRHATERVAY----------------KLRKLAE-------NEKVFD 305
Query: 292 ALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWRYSE 351
+ + HH+ L RD R+ VE+ +KG++KVVV++ +L GI+ ++I + S
Sbjct: 306 --VDAIEAHHSSLSRDVRLDVEEKLKKGILKVVVSSTSLELGIDIGYIDLVILLSSPKS- 362
Query: 352 FGMERIPVLEVQQMMGRAGRP-RYDEVGEAIIV 383
V + Q +GRAG R G I+V
Sbjct: 363 -------VSRLLQRIGRAGHHIRSISKGRVIVV 388
>sp|P95949|HELX_SULSO PUTATIVE ATP-DEPENDENT HELICASE C04010 >gi|7446117|pir||S75377
probable helicase LHR - Sulfolobus solfataricus
>gi|1707782|emb|CAA69580.1| (Y08257) ATP-dependent
helicase [Sulfolobus solfataricus]
Length = 875
Score = 101 bits (248), Expect = 4e-20
Identities = 110/393 (27%), Positives = 180/393 (44%), Gaps = 72/393 (18%)
Query: 26 PPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLEEGGK--------AVYIVPL 77
PPQ A+ + + N+LV+ PT SGKTL A + I + L E G A+YI PL
Sbjct: 33 PPQRAAIPL-IKQNYNVLVSSPTGSGKTLAAFLGILDSLFELGDNNELEDKVYAIYISPL 91
Query: 78 KALAEEKFREFKD-------------WERLGLKVAMATGDYDSKDEWLGKYDIIIATAEK 124
+AL + R + R+G++ + T Y+ + I+I T E
Sbjct: 92 RALNNDMQRNLLEPLNELRQVNSKLPDVRVGIRTSDTT-PYEKQKMLKKPPHILITTPES 150
Query: 125 FDSLLRHG--SSWIRDVKMLVIDEIHLIGSRDRGATLEFII---TQMLGRAQI--IGLSA 177
F + S + DVK +++DEIH + + RGA L ++ ++ + + IGLSA
Sbjct: 151 FGISITSPKFSQKLTDVKWIIVDEIHELANSKRGAYLSAMLELFRNLITKKEFVRIGLSA 210
Query: 178 TIGNPEELAEWLNAK-----LIRSDW-RPVKLRKGVFYQGFVFWEDGGSERYNSWEELVY 231
T+ EE+A++L K ++ + + +PV ++ + V SE + +
Sbjct: 211 TVSPLEEVAQFLVGKDREYRIVDARFVKPVDIKVISPVKDLV--HSSESEVDKGIYKTIL 268
Query: 232 DAVKKGKGALVFVNMRRKAEKTALELAKKVKNYLDRKELRELRELAESLEENPTNEKLAK 291
+ VKK + L+F N R E+ A +LR+LAE NEK+
Sbjct: 269 NEVKKHRTTLIFTNTRHATERVAY----------------KLRKLAE-------NEKVFD 305
Query: 292 ALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWRYSE 351
+ + HH+ L RD R+ VE+ +KG++KVVV++ +L GI+ ++I + S
Sbjct: 306 --VDAIEAHHSSLSRDVRLDVEEKLKKGILKVVVSSTSLELGIDIGYIDLVILLSSPKS- 362
Query: 352 FGMERIPVLEVQQMMGRAGRP-RYDEVGEAIIV 383
V + Q +GRAG R G I+V
Sbjct: 363 -------VSRLLQRIGRAGHHIRSISKGRVIVV 388
>pir||D75091 large helicase-related protein (lhr-2) PAB0744 - Pyrococcus abyssi
(strain Orsay) >gi|5458545|emb|CAB50033.1| (AJ248286)
large helicase-related protein (lhr-2) [Pyrococcus
abyssi]
Length = 867
Score = 100 bits (246), Expect = 7e-20
Identities = 120/472 (25%), Positives = 200/472 (41%), Gaps = 87/472 (18%)
Query: 18 ERGIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLEEGGK------- 70
+R + PPQ A+ + +GEN+L++ PT SGKTL A +AI ++L+ G +
Sbjct: 30 KRKFKSFTPPQRYAIVE-IHKGENVLISSPTGSGKTLSAFLAIISELISLGRRGKLEDKI 88
Query: 71 -AVYIVPLKAL-------AEEKFREFKDW------ERLGLKVAMATGD---YDSKDEWLG 113
VY+ PL+AL EE +E ++ E ++VA+ T D Y+
Sbjct: 89 YCVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRTSDTSSYEKSKMLKM 148
Query: 114 KYDIIIATAEKFDSLLR--HGSSWIRDVKMLVIDEIHLIGSRDRGATLEFIITQMLGRAQ 171
I+I T E L +RDVK +++DE+H + RG+ L + ++ +
Sbjct: 149 PPHILITTPESLAIALNAPRFREKLRDVKWVIVDEVHALAENKRGSHLALTLERLRELTK 208
Query: 172 ----IIGLSATIGNPEELAEWLNAKLIRSDWRP-------VKLRKGVFYQGFVFWEDGGS 220
IGLSATI EE+A+++ D +P V K ED
Sbjct: 209 RDFVRIGLSATIHPLEEVAKFVFG--FSDDGKPRPGLIVDVSFAKKTKITVESVVEDLVY 266
Query: 221 ERYNSWEELVY----DAVKKGKGALVFVNMRRKAEKTALELAKKVKNYLDRKELRELREL 276
N E +Y + V+ K L+F N R AE+ A L K + D+ E
Sbjct: 267 TPANVLNEALYRRIGELVRSRKTTLIFTNTRSGAERVAYHLKKMFPEWEDKIEA------ 320
Query: 277 AESLEENPTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINT 336
HH+ L R+ R+ VE+ ++G +K++V++ +L GI+
Sbjct: 321 -----------------------HHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDI 357
Query: 337 PAFRVIIRDTWRYSEFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTE----EPSLV 392
++I G + V Q +GRAG R EV E +I++ E +++
Sbjct: 358 GTIDLVIL-------IGSPK-SVNRALQRIGRAGH-RLHEVSEGVILALDRDDLVEVTVL 408
Query: 393 IDHYIKGKPEKLFSQLSNESILRSQILALIATFGYSEFKEIYDFLERTFYAH 444
+ K K +++ + +L +L + A E +E Y + R + H
Sbjct: 409 AHNARKRKLDRIKIPKNPLDVLVQHLLGM-ALERVWEVEEAYKVVRRAYPYH 459
>emb|CAB59484.1| (AL132648) putative helicase [Streptomyces coelicolor A3(2)]
Length = 950
Score = 99.5 bits (244), Expect = 1e-19
Identities = 80/258 (31%), Positives = 129/258 (49%), Gaps = 34/258 (13%)
Query: 24 LYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLEEGGKAVYIVPLKALAEE 83
L P Q EA + + G+ +LVA PT SGKT++ E A+ + L++G K Y P+KAL+ +
Sbjct: 51 LDPFQIEACQA-LEAGKGVLVAAPTGSGKTIVGEFAV-HLALQQGRKCFYTTPIKALSNQ 108
Query: 84 KFREFKDWERLGL-KVAMATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSSWIRDVKML 142
K+ + R G KV + TGD E +++ T E ++L GS + + +
Sbjct: 109 KYADL--CRRYGTDKVGLLTGDNSVNSE----APVVVMTTEVLRNMLYAGSQTLLGLGHV 162
Query: 143 VIDEIHLIGSRDRGATLEFIITQMLGRAQIIGLSATIGNPEELAEWL-----NAKLIRSD 197
V+DE+H + R RGA E +I + ++ LSAT+ N EE +WL + ++I S+
Sbjct: 163 VMDEVHYLSDRFRGAVWEEVIIHLPESVTLVSLSATVSNAEEFGDWLDTVRGDTQVIVSE 222
Query: 198 WRPVKLRKGVFYQGFVFWEDGGSERYNSWEELVYDAVKKGKGALVFVNMRRKAEKTALEL 257
RPV L + V G Y+ +EE +G V ++ R A LE
Sbjct: 223 HRPVPLFQHVL---------AGRRMYDLFEE------AEGHKKAVNPDLTRMAR---LEA 264
Query: 258 AKKVKNYLDRKELRELRE 275
++ +Y DR+ R ++E
Sbjct: 265 SR--PSYQDRRRGRAMKE 280
>gb|AAK41239.1| ATP-dependent helicase [Sulfolobus solfataricus]
Length = 933
Score = 99.1 bits (243), Expect = 2e-19
Identities = 124/492 (25%), Positives = 209/492 (42%), Gaps = 85/492 (17%)
Query: 7 NVSEKIKEILRERGIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLE 66
++ +++++++ E+ +L Q E + G N LV PT GKT A + I N++L+
Sbjct: 4 HLDQRLRKLIEEKNWMKLTRVQ-EMSFEPISNGYNTLVIAPTGYGKTEAALLPILNRMLK 62
Query: 67 EGGK---AVYIVPLKALAEEKFREFKDW-ERLGLKVAMATGDYDSKDEWLGKY---DIII 119
E K +YI PLKAL + W RLG V G+ K++ L II+
Sbjct: 63 EDVKPVTVIYITPLKALINDLLYRIDWWASRLGFLVNRKHGEVPQKEKNLRLKRIPHIIV 122
Query: 120 ATAEKFDSLLRHGSSW---IRDVKMLVIDEIHLIGSRDRGATLEFIITQM---LG-RAQI 172
T E + L S + ++VK +V+DEIH + + RG L ++ ++ +G Q
Sbjct: 123 TTPEGLEIDLDWASRFREHYKNVKWVVVDEIHELINSKRGTQLSILLERLKYFIGYDFQR 182
Query: 173 IGLSATIGNPEELAEWL------NAKLIR-SDWR--PVKLRKGVFYQGFVFWEDGGSERY 223
IGLSAT+ + +++A++L K+IR +D R +K+ K F W+ +E+
Sbjct: 183 IGLSATVSDEDKVAQFLFGSSERKMKIIRLNDTRNFEIKINKLGNDNSFALWK-SAAEKI 241
Query: 224 NSWEELVYDAVKKGKGALVFVNMRRKAEKTALELAKKVKNYLDRKELRELRELAESLEEN 283
N E K LVF N R E+ EL K L KE
Sbjct: 242 NQLIE---------KPTLVFTNSRFSTERLHEELEK-----LGNKE-------------- 273
Query: 284 PTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVII 343
+ HH+ + RD + L E R G K VV T TL GI+ + +I
Sbjct: 274 -------------IYVHHSSVSRDLKNLAEGELRNGNAKAVVCTKTLELGIHVGDIKKVI 320
Query: 344 RDTWRYSEFGMERIP--VLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKGKP 401
M R P V Q +GR+G + II + + Y+ K
Sbjct: 321 ----------MLRPPTSVSSFLQRLGRSGHIVHGVPKGEIICFYDFDVLESLALYLSAKD 370
Query: 402 EKLFSQLSNE--SILRSQILALIATFGYSEFKEIYDFLERTFYAHQGKDPYMLEEKIRRI 459
K+ ++ ++ +I+ +I +EI++ + T+ + K+ +
Sbjct: 371 GKMEKPFIDDGLDVVAREIVGMILQNQKMSIEEIFNIIRGTYIYRN-----LELSKLLDL 425
Query: 460 IYFLLENEFIEV 471
+ +L++N I++
Sbjct: 426 VNYLVKNNIIKI 437
>pir||T35049 probable ATP-dependent helicase - Streptomyces coelicolor
>gi|3483040|emb|CAA20551.1| (AL031371) putative
ATP-dependent helicase [Streptomyces coelicolor A3(2)]
Length = 731
Score = 98.7 bits (242), Expect = 2e-19
Identities = 110/398 (27%), Positives = 174/398 (43%), Gaps = 48/398 (12%)
Query: 12 IKEILRERGIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLEE---G 68
+ I+ G +L P Q A+T ++EGE+ ++ PTA GKT A + + + E+ G
Sbjct: 24 LHHIVNTLGWSDLRPLQRAAITP-LMEGEDAVLLAPTAGGKTEAACFPLLSAMAEQKWTG 82
Query: 69 GKAVYIVPLKALAEE---KFREFKDWERLGLKVAMATGDYDSKDEWLGKY---DIIIATA 122
+Y+ PLKAL + + W LG + A+ GD + D+++ T
Sbjct: 83 TSVLYLCPLKALLNNLVSRVDTYTQW--LGRRAALWHGDTKESQRQRIRTEAPDVLLTTP 140
Query: 123 EKFDSLL----RHGSSWIRDVKMLVIDEIHLIGSRDRGATLEFIIT---QMLGRA-QIIG 174
E +++L + + V+ +V+DE+H DRG L ++ Q+ GR Q IG
Sbjct: 141 ESLEAMLIGVKTDHARLLGSVRAVVVDEVHAFAGDDRGWHLLAVLERLEQVTGRPIQRIG 200
Query: 175 LSATIGNPEELAEWLNAKLIRSDWRPVKLRKGVFYQGFVFWEDGGSERYNSWEELVYDAV 234
LSAT+GNP++L +WL + + V + GV F E GS+R + EE+ A
Sbjct: 201 LSATVGNPDQLLDWLQGAGVETRAGRV-VAPGVTLPAF---EAVGSDRKPTAEEVPRPA- 255
Query: 235 KKGKGALVFVNMRRKAEKTALELAKKVKNYLDRKELRELRELAESLEENPTNEKLAKALL 294
G+ L +V A K L + K + ++ +L +L
Sbjct: 256 --GEVELDYVGSLDNAAKLIATLHRGEKRLVFCDSRAQVEQLGAALRAREVT-------- 305
Query: 295 SGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAF-RVIIRDTWRYSEFG 353
V HA L DER E F + V+V+T TL GI+ RVI D+
Sbjct: 306 --VFLSHASLSVDERTRSEQAFAEARDCVIVSTSTLELGIDVGDLDRVIQIDS------- 356
Query: 354 MERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSL 391
V Q +GR GR R V + ++T ++ L
Sbjct: 357 --PATVASFLQRIGRTGR-RAGTVRNCLFLTTRKDTLL 391
>pir||T20487 hypothetical protein F01G4.3 - Caenorhabditis elegans
>gi|3875462|emb|CAA92767.1| (Z68341) Similarity to Yeast
antiviral protein SKI2 (SW:SKI2_YEAST), contains
similarity to Pfam domain: PF00270 (DEAD/DEAH box
helicase), Score=97.9, E-value=1.5e-30, N=1~cDNA EST
yk35h8.3 comes from this gene~cDNA EST yk35h8.5 comes
from this gene~cD>
Length = 1260
Score = 98.7 bits (242), Expect = 2e-19
Identities = 66/171 (38%), Positives = 99/171 (57%), Gaps = 14/171 (8%)
Query: 39 GENLLVAIPTASGKTLIAEIAIANKLLEEGGKAVYIVPLKALAEEKFREFKDWERLGLKV 98
GE+L VA T++GKT++AE AIA + +AVY P+KAL+ +KFR+FK ++ V
Sbjct: 301 GESLFVAAHTSAGKTVVAEYAIALCQAHKT-RAVYTSPIKALSNQKFRDFK---QIFGDV 356
Query: 99 AMATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSSWIRDVKMLVIDEIHLIGSRDRGAT 158
+ TGD E +I T E S+L +GS IRD++ +V DE+H I + +RG
Sbjct: 357 GLVTGDIQLHPEAA----CLIMTTEILRSMLYNGSEVIRDLEWVVFDEVHYINNEERGHV 412
Query: 159 LEFIITQMLGRAQIIGLSATIGNPEELAEWL----NAKL--IRSDWRPVKL 203
E ++ + +I+ LSAT+ N E A+W+ N K+ I +D RPV L
Sbjct: 413 WEEVLIMLPAHVKIVMLSATVPNCVEFADWVGRIKNRKINVISTDRRPVPL 463
>pir||A70982 probable ATP-dependent helicase lhr - Mycobacterium tuberculosis
(strain H37RV) >gi|1877351|emb|CAB07060.1| (Z92771) lhr
[Mycobacterium tuberculosis]
Length = 1513
Score = 97.9 bits (240), Expect = 3e-19
Identities = 103/366 (28%), Positives = 163/366 (44%), Gaps = 58/366 (15%)
Query: 26 PPQAEALT-SGVLEGENLLVAIPTASGKTLIAEIAIANKLLEE--------GGKAVYIVP 76
P A+A + + +G+N LV PT SGKTL A + + L + +Y+ P
Sbjct: 27 PTAAQASAWAAIADGDNTLVIAPTGSGKTLAAFLWALDSLAGSEPMSERPAATRVLYVSP 86
Query: 77 LKALAEEKFREFKD--------WERLGL-----KVAMATGDYDS---KDEWLGKYDIIIA 120
LKALA + R + ER GL +V + +GD + D++I
Sbjct: 87 LKALAVDVERNLRTPLAGLTRLAERQGLPAPQIRVGVRSGDTPPALRRQLVSQPPDVLIT 146
Query: 121 TAEKFDSLLRHGS-SWIRDVKMLVIDEIHLIGSRDRGATLEFIITQM-----LGRAQIIG 174
T E +L + + V+ ++IDEIH I + RGA L + ++ RAQ IG
Sbjct: 147 TPESLFLMLTSAARQTLTGVQTVIIDEIHAIAATKRGAHLALSLERLDDLSSRRRAQRIG 206
Query: 175 LSATIGNPEELAEWLNAKLIRSDWRPVKLRKGVFYQGFVFWEDGGSERYNS-WEEL---V 230
LSAT+ PEELA +L+ + + P K V V D + N+ W ++ +
Sbjct: 207 LSATVRPPEELARFLSGQSPTTIVAP-PAAKTVELSVQVPVPDMANLTDNTIWPDVEARL 265
Query: 231 YDAVKKGKGALVFVNMRRKAEKTALELAKKVKNYLDRKELRELR---ELAESLEENPTNE 287
D ++ +VF N RR AE+ L E+ R ELA +
Sbjct: 266 VDLIESHNSTIVFANSRRLAERLTARL----------NEIHAARCGIELAPDTNQQVAGG 315
Query: 288 KLAKALLSGVAF---------HHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPA 338
A + SG F HH + +++R +VE++ ++G +K VVAT +L GI+ A
Sbjct: 316 APAHIMGSGQTFGAPPVLARAHHGSISKEQRAVVEEDLKRGQLKAVVATSSLELGIDMGA 375
Query: 339 FRVIIR 344
++I+
Sbjct: 376 VDLVIQ 381
>dbj|BAB05483.1| (AP001513) ATP-dependent RNA helicase [Bacillus halodurans]
Length = 764
Score = 96.7 bits (237), Expect = 8e-19
Identities = 120/474 (25%), Positives = 206/474 (43%), Gaps = 64/474 (13%)
Query: 11 KIKEILRERGIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKL-LEEGG 69
+I+E L +RGI +LY Q A +GE+++ PTASGKTL + + ++ +E
Sbjct: 46 RIREALEKRGIGQLYTHQNTAYECSE-KGEHVVAVTPTASGKTLCYNLPVLQQIRRDESS 104
Query: 70 KAVYIVPLKALAEEKFREFKD-WERLGLKVAMATGDYDSKD---EWLGKYDIIIATAEKF 125
+A+Y+ P KALA+++ E + E +G+ V T D D+ + + K ++ T
Sbjct: 105 RALYLFPTKALAQDQKSELNEIIEEMGISVKCFTYDGDTAPNIRQAVRKAGHVVITNPDM 164
Query: 126 --DSLLRHGSSWI---RDVKMLVIDEIH----LIGSRDRGA--TLEFIITQMLGRAQIIG 174
++L H + W+ ++K +VIDE+H + GS L+ I I
Sbjct: 165 LHSAILPHHTKWVAFFENLKYVVIDELHTYRGVFGSHVANVIRRLKRIARYYGSEPTFIC 224
Query: 175 LSATIGNPEELAEWL---NAKLIRSDWRPVKLRKGVFYQGFVFWEDGGSERYNSWEELVY 231
SATI NP+ELA L N +LI ++ P + VFY +V
Sbjct: 225 TSATIANPQELASQLTGHNVRLIDNNGAPSGKKHFVFYN----------------PPVVN 268
Query: 232 DAVKKGKGALVFVNMRRKAEKTALELAKKVKNYLDRKELRELRELAESLEENPTNEKLAK 291
+ + K A V VN R A+K L ++ + + + + L+E T +K+ +
Sbjct: 269 EPLNIRKSATVEVN--RLAKKF---LENNIQTIVFARSRVRVEVILSHLQE-LTKKKIGQ 322
Query: 292 ALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWRYSE 351
+ G + G +R +E R G I VV+T L G++ +V I + S
Sbjct: 323 QAVRG---YRGGYLPKQRREIERGLRNGDIIGVVSTNALELGVDIGQLQVCIMTGYPGS- 378
Query: 352 FGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLV--IDHYIKGKPEKLFSQLS 409
+ Q GRAGR +++ + + S+ + ++ D++++ PE +
Sbjct: 379 -------IASAWQQSGRAGRRQHESLTLLVAGSSPIDQYMIQHPDYFLEKSPESVRINRD 431
Query: 410 NESILRSQILALI--------ATFGYSEFKEIYDFL-ERTFYAHQGKDPYMLEE 454
N IL + T E +EI +FL E H+G Y + +
Sbjct: 432 NLIILVDHLKCAAYELPFKEGETLDGVEIEEILEFLTEEHVLHHRGSKWYWMND 485
>gb|AAA35049.1| (L13469) antiviral protein [Saccharomyces cerevisiae]
Length = 1286
Score = 96.3 bits (236), Expect = 1e-18
Identities = 59/177 (33%), Positives = 96/177 (53%), Gaps = 12/177 (6%)
Query: 38 EGENLLVAIPTASGKTLIAEIAIANKLLEEGGKAVYIVPLKALAEEKFREFKDWERLGLK 97
+G+++ VA T++GKT++AE AIA K +Y P+KAL+ +KFR+FK+ +
Sbjct: 343 QGDSVFVAAHTSAGKTVVAEYAIA-MAHRNMTKTIYTSPIKALSNQKFRDFKETFD-DVN 400
Query: 98 VAMATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSSWIRDVKMLVIDEIHLIGSRDRGA 157
+ + TGD + + +I T E S+L G+ IRDV+ ++ DE+H + +DRG
Sbjct: 401 IGLITGDVQINPD----ANCLIMTTEILRSMLYRGADLIRDVEFVIFDEVHYVNDQDRGV 456
Query: 158 TLEFIITQMLGRAQIIGLSATIGNPEELAEWL------NAKLIRSDWRPVKLRKGVF 208
E +I + + I LSAT+ N E A W+ N +I + RPV L ++
Sbjct: 457 VWEEVIIMLPQHVKFILLSATVPNTYEFANWIGRTKQKNIYVISTPKRPVPLEINIW 513
>gi|6323430 antiviral protein, putative helicase; Ski2p [Saccharomyces
cerevisiae] >gi|8489004|sp|P35207|SKI2_YEAST ANTIVIRAL
PROTEIN SKI2 >gi|1084512|pir||S55954 viral mRNA
translation inhibitor SKI2 - yeast (Saccharomyces
cerevisiae) >gi|625114|gb|AAB82356.1| (U19729) Ski2p:
Antiviral protein [Saccharomyces cerevisiae]
Length = 1287
Score = 96.3 bits (236), Expect = 1e-18
Identities = 59/177 (33%), Positives = 96/177 (53%), Gaps = 12/177 (6%)
Query: 38 EGENLLVAIPTASGKTLIAEIAIANKLLEEGGKAVYIVPLKALAEEKFREFKDWERLGLK 97
+G+++ VA T++GKT++AE AIA K +Y P+KAL+ +KFR+FK+ +
Sbjct: 343 QGDSVFVAAHTSAGKTVVAEYAIA-MAHRNMTKTIYTSPIKALSNQKFRDFKETFD-DVN 400
Query: 98 VAMATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSSWIRDVKMLVIDEIHLIGSRDRGA 157
+ + TGD + + +I T E S+L G+ IRDV+ ++ DE+H + +DRG
Sbjct: 401 IGLITGDVQINPD----ANCLIMTTEILRSMLYRGADLIRDVEFVIFDEVHYVNDQDRGV 456
Query: 158 TLEFIITQMLGRAQIIGLSATIGNPEELAEWL------NAKLIRSDWRPVKLRKGVF 208
E +I + + I LSAT+ N E A W+ N +I + RPV L ++
Sbjct: 457 VWEEVIIMLPQHVKFILLSATVPNTYEFANWIGRTKQKNIYVISTPKRPVPLEINIW 513
Score = 74.5 bits (180), Expect = 4e-12
Identities = 71/261 (27%), Positives = 115/261 (43%), Gaps = 19/261 (7%)
Query: 214 FWEDGGSERYNSWEELV-YDAVKKGKGALVFVNMRRKAEKTALELA------KKVKNYLD 266
F +DG S++ +W E+V Y ++ +VFV +++ E+ A L K K+ +
Sbjct: 604 FTQDGPSKK--TWPEIVNYLRKRELLPMVVFVFSKKRCEEYADWLEGINFCNNKEKSQIH 661
Query: 267 RKELRELRELAESLEENPTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVA 326
+ + L + + P K L G+A HH GL + L+E F KG IKV+ A
Sbjct: 662 MFIEKSITRLKKEDRDLPQILKTRSLLERGIAVHHGGLLPIVKELIEILFSKGFIKVLFA 721
Query: 327 TPTLSAGINTPAFRVIIRDTWRYSEFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTT 386
T T + G+N P VI ++ G+ + E QM GRAGR D G I+++
Sbjct: 722 TETFAMGLNLPTRTVIFSSIRKHDGNGLRELTPGEFTQMAGRAGRRGLDSTGTVIVMAYN 781
Query: 387 EEPSL-VIDHYIKGKPEKLFSQLSNE-----SILRSQILALIATFGYSEFKEIYDFLERT 440
S+ G P +L SQ ++LR + L + YS + + T
Sbjct: 782 SPLSIATFKEVTMGVPTRLQSQFRLTYNMILNLLRIEALRVEEMIKYS----FSENAKET 837
Query: 441 FYAHQGKDPYMLEEKIRRIIY 461
K +L+E+++ I Y
Sbjct: 838 LQPEHEKQIKVLQEELQTIEY 858
>pir||T35694 ATP dependent DNA helicase - Streptomyces coelicolor
>gi|3294249|emb|CAA19862.1| (AL031031) ATP dependent DNA
helicase [Streptomyces coelicolor A3(2)]
Length = 1690
Score = 95.2 bits (233), Expect = 2e-18
Identities = 117/457 (25%), Positives = 200/457 (43%), Gaps = 81/457 (17%)
Query: 26 PPQAEA-LTSGVLEGENLLVAIPTASGKTLIAEIAIANKLL--------EEGGKAVYIVP 76
P A+A + +G ++LV PT SGKTL A +A ++L ++ + +Y+ P
Sbjct: 27 PTSAQAGAWQAISQGSDVLVVAPTGSGKTLAAFLAALDQLTSTPPPADPKKRCRVLYVSP 86
Query: 77 LKALAEEKFREFK--------DWERLGL-----KVAMATGDYDSKDE---WLGKYDIIIA 120
LKALA + R + + RLGL KV + +GD + + DI+I
Sbjct: 87 LKALAVDVERNLRSPLTGIRQESVRLGLPEPEVKVGIRSGDTPAAERRALSTRPPDILIT 146
Query: 121 TAEKFDSLLRHGS-SWIRDVKMLVIDEIHLIGSRDRGA----TLEFIITQMLGRAQIIGL 175
T E +L + + ++ +++DE+H + RGA TLE + + A+ IGL
Sbjct: 147 TPESLFLMLTSATRDALTGIETVILDEVHAVAGTKRGAHLALTLERLDELLPKPARRIGL 206
Query: 176 SATIGNPEELAEWLNAKLIRSDWRPVKLRK------------GVFYQGFVFWEDGGSERY 223
SAT+ +E+A +L + +P ++ G V + G+ER
Sbjct: 207 SATVRPVDEVARFLAPRGRVEIVQPESGKEFDLSVVVPVEDLGELGGSPVAEGNEGAERP 266
Query: 224 NSW---EELVYDAVKKGKGALVFVNMRRKAEKTALELAKKVKNYLDRKELRELRELAESL 280
+ W EE + D V+ + +VF N RR AE+ L E+ R E L
Sbjct: 267 SIWPHVEERITDLVQSHRSTIVFANSRRLAERLCNRL----------NEIAYERATGEPL 316
Query: 281 EENPTNEKLAKALLSGVA---------FHHAGLGRDERVLVEDNFRKGLIKVVVATPTLS 331
+E+ + +L SG A HH + +++R LVE++ + G + VVAT +L
Sbjct: 317 DEHHSPAELMGG--SGAAQGAPPVIARAHHGSVSKEQRALVEEDLKAGRLPAVVATSSLE 374
Query: 332 AGINTPAFRVIIRDTWRYSEFGMERIP-VLEVQQMMGRAGRPRYDEVGEAIIV----STT 386
GI+ A ++++ +E P V Q +GRAG + V ++
Sbjct: 375 LGIDMGAVDLVVQ---------VESPPSVASGLQRVGRAGH-QVGAVSTGVVFPKYRGDL 424
Query: 387 EEPSLVIDHYIKGKPEKLFSQLSNESILRSQILALIA 423
+ ++V + G E L + +L Q++A+ A
Sbjct: 425 VQSAVVTERMRSGAIEALRIPANPLDVLAQQLVAMTA 461
>pir||G71051 probable ATP-dependent helicase LHR - Pyrococcus horikoshii
>gi|3257526|dbj|BAA30209.1| (AP000005) 1352aa long
hypothetical ATP-dependent helicase LHR [Pyrococcus
horikoshii]
Length = 1352
Score = 95.2 bits (233), Expect = 2e-18
Identities = 98/353 (27%), Positives = 160/353 (44%), Gaps = 81/353 (22%)
Query: 18 ERGIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLEEGGK------- 70
+R PPQ A+ + +GEN+L++ PT SGKTL A +AI ++L+ G K
Sbjct: 30 KRKFNSFTPPQRYAIVE-IHKGENVLISSPTGSGKTLSAFLAIISELISLGRKGKLEDKI 88
Query: 71 -AVYIVPLKAL-------AEEKFREFKDW-ERLG-----LKVAMATGDYDS--KDEWLGK 114
VYI PL+AL EE RE K+ + LG +++A+ T D S K + + K
Sbjct: 89 YCVYISPLRALNNDIRRNLEEPLREIKELAQELGEEIPEIRIAVRTSDTSSYEKSKMVKK 148
Query: 115 YDIIIATAEKFDSLLRHGSSW---IRDVKMLVIDEIHLIGSRDRGATLEFI---ITQMLG 168
I+ T + ++ + + +RDV+ +++DE+H + RG+ L + +++G
Sbjct: 149 PPHILITTPESLAIALNAPKFRERLRDVRWVIVDEVHALAENKRGSHLALTLERLRELVG 208
Query: 169 RAQI-IGLSATIGNPEELAEWLNAKLIRSDWRP---------------VKLRKGVFYQGF 212
R + IGLSATI EE+A+++ D P +K+ V +
Sbjct: 209 RDFVRIGLSATIHPLEEVAKFVFG--FNDDGTPRSGLIVDVSFAKQTEIKVESVVEDLIY 266
Query: 213 VFWEDGGSERYNSWEELVYDAVKKGKGALVFVNMRRKAEKTALELAKKVKNYLDRKELRE 272
E + YN EL ++K K L+F N R AE+ A L +K E
Sbjct: 267 TDAETLSNALYNRLAEL----IRKHKTTLIFTNTRSGAERVAFNL---------KKRFPE 313
Query: 273 LRELAESLEENPTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVV 325
+ L E+ HH+ L R+ R+ VE+ ++G ++ VV
Sbjct: 314 FKGLIET--------------------HHSSLSREVRLDVEEKLKRGELRAVV 346
>gb|AAK40384.1| ATP-dependent helicase [Sulfolobus solfataricus]
Length = 739
Score = 94.0 bits (230), Expect = 5e-18
Identities = 113/427 (26%), Positives = 177/427 (40%), Gaps = 87/427 (20%)
Query: 3 VGELNVSEKIKEILRERGIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIAN 62
+ E+++ +K+K+ + E GIE LY Q +A + EN+++ T +GKT I I +
Sbjct: 35 INEIDIDDKLKKSIIEYGIERLYKYQYDAYRK-IKNKENVMIISGTGTGKTEAFLIPILD 93
Query: 63 KLLEEGGKAVYIVPLKALAEEKF-REFKDWERLGLKVAMATGDYDSKDE----------W 111
L+ G ++V + P KALA ++ R +K LGL V + GD K+
Sbjct: 94 LALK-GERSVLVYPTKALARDQLTRVYKLARELGLNVGIFDGDTPEKERERLYRNPPHIL 152
Query: 112 LGKYDII---IATAEKFDSLLRHGSSWIRDVKMLVIDEIHL----IGSRDRGATLEFIIT 164
+ D+I +A + +F LLR +I DE+H+ +G+ R L I
Sbjct: 153 ITNPDMIHLGLALSTRFRFLLRTADHFI-------FDEVHVYEGVLGAHIRN--LADRIK 203
Query: 165 QMLGRAQIIGLSATIGNPEELAEWL---NAKLIRSDWRPVKLRKGVFYQGFVFWEDGGSE 221
+ I+ SAT+G + L E L ++I ++ RKG+ + + G S
Sbjct: 204 EFKNDIHIVASSATVGATKYLFEELFGVEGEIIEG----IRRRKGIAIHSII--DSGNSS 257
Query: 222 RYNSWEELVYDAVKKGKGALVFVNMRRKAEKTALELAKKVKNYLDRKELRELRELAESLE 281
R+ L VK G LVF + ++ AE A
Sbjct: 258 RWTLAAYLAAVLVKNGLKVLVFTDSQQMAELVA--------------------------- 290
Query: 282 ENPTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRV 341
K+A + H AGL +ER+ VE+ R G + VVATPTL GI+
Sbjct: 291 ------KIADRFRVNLEVHRAGLIAEERIKVEEKLRNGELDGVVATPTLELGIDIGTIDA 344
Query: 342 IIRDTWRYSEFGMERIP-VLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKGK 400
+I E P + Q GRAGR + ++P ID Y
Sbjct: 345 VIM---------AENPPSYTKYVQRAGRAGRRNN---AGLVFTILGDDP---IDSYYLRH 389
Query: 401 PEKLFSQ 407
PE+ F++
Sbjct: 390 PEEFFTR 396
>pir||T45632 helicase homolog F13I12.10 - Arabidopsis thaliana
>gi|6522577|emb|CAB61942.1| (AL133292) putative helicase
[Arabidopsis thaliana]
Length = 1347
Score = 93.6 bits (229), Expect = 7e-18
Identities = 65/217 (29%), Positives = 114/217 (51%), Gaps = 19/217 (8%)
Query: 7 NVSEKIKEILRERGIE---ELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANK 63
+++++ E++ + IE EL Q EA+ + +GE++ VA T++GKT++AE A A
Sbjct: 332 DIADRFYELVPDMAIEFPFELDNFQKEAICC-LEKGESVFVAAHTSAGKTVVAEYAFA-L 389
Query: 64 LLEEGGKAVYIVPLKALAEEKFREFKDWERLGLKVAMATGDYDSKDEWLGKYDIIIATAE 123
+ +AVY P+K ++ +K+R+F +GL TGD + E +I T E
Sbjct: 390 ATKHCTRAVYTAPIKTISNQKYRDFCGKFDVGL----LTGDVSIRPE----ASCLIMTTE 441
Query: 124 KFDSLLRHGSSWIRDVKMLVIDEIHLIGSRDRGATLEFIITQMLGRAQIIGLSATIGNPE 183
S+L G+ IRD++ ++ DE+H + +RG E +I + + LSAT+ N
Sbjct: 442 ILRSMLYRGADIIRDIEWVIFDEVHYVNDVERGVVWEEVIIMLPRHINFVLLSATVPNTF 501
Query: 184 ELAEWL------NAKLIRSDWRPVKLRKGVFYQGFVF 214
E A+W+ ++ + RPV L +FY G ++
Sbjct: 502 EFADWIGRTKQKEIRVTGTTKRPVPLEHCLFYSGELY 538
>pir||F69164 ATP-dependent RNA helicase homolog MTH492 - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2621563|gb|AAB84998.1| (AE000833) ATP-dependent RNA
helicase, eIF-4A family [Methanobacterium
thermoautotrophicum]
Length = 822
Score = 92.8 bits (227), Expect = 1e-17
Identities = 113/437 (25%), Positives = 187/437 (41%), Gaps = 69/437 (15%)
Query: 7 NVSEKIKEILRERGIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKL-L 65
++ + I++ L GI LY Q EAL + + EG N+L+ PTASGKTL + I L L
Sbjct: 37 DIPDNIRDYLDAGGIR-LYRHQREALDA-IREGMNILITTPTASGKTLAFNLPIMETLTL 94
Query: 66 EEGGKAVYIVPLKALAEEKFREFKDWE-RLGLKVAMATGDYDSKDE---WLGKYD-IIIA 120
A+YI P+KAL+ ++ ++ E LGLK+ +T D D+ E W+ + +I+
Sbjct: 95 NPDATALYIYPVKALSRDQLGVLEELESELGLKLNPSTYDGDTPRERRPWIRENSRVILT 154
Query: 121 TAEKFDSLLRHGSSWIR---DVKMLVIDEIH----LIGSRDR--GATLEFIITQMLGRAQ 171
+ +L W R +++ +VIDE H + GS L I Q
Sbjct: 155 NPHQLHRILPWHHQWRRFYSNLRYVVIDEAHQYRGVFGSNVALLLRRLRRICRYYGSEPQ 214
Query: 172 IIGLSATIGNPEELAE---WLNAKLIRSDWRPVKLRKGVFYQGFVFWEDGGSERYNSWEE 228
+ SAT+ NP E + L+ ++I D P + + Y + + G +
Sbjct: 215 FVLASATLANPAEFSRKLTGLDFRVISDDTSPSGPKHFILYN--PYRKRGDPSAHLETSA 272
Query: 229 LVYDAVKKGKGALVFVNMRRKAEKTALELAKKVKNYLDRKELRELRELAESLEENPTNEK 288
++ V +G L F R+ AE + + + LDR+
Sbjct: 273 ILSYLVLRGVQTLCFTISRKMAEL----VTRWTREQLDREN------------------- 309
Query: 289 LAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWR 348
+ L+ V + AG ++R +E + ++G + V AT L GI+ + +I +
Sbjct: 310 --RKLVDRVTSYRAGYLAEQRRRIEADLKEGRLLGVTATNALELGIDIGSLDAVIISGYP 367
Query: 349 YSEFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKGKPEKLFSQ- 407
+ ++ Q GRAGR D + +I+ E P +D YI P +F +
Sbjct: 368 GT--------MISTWQQAGRAGRNLKDSM---VILVAFENP---LDQYIMKNPSFIFERP 413
Query: 408 -------LSNESILRSQ 417
L N ILR+Q
Sbjct: 414 HENAIIDLQNRLILRNQ 430
>gi|11500031 large helicase-related protein (lhr-2) [Archaeoglobus fulgidus]
Length = 862
Score = 92.1 bits (225), Expect = 2e-17
Identities = 104/402 (25%), Positives = 173/402 (42%), Gaps = 83/402 (20%)
Query: 23 ELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLEEGGK--------AVYI 74
E PPQ A+ +G N+L+ PT SGKTL A +A + L+E+ K VY+
Sbjct: 31 EFTPPQKYAIVEA-FKGRNVLITSPTGSGKTLAAFLAAISMLVEKAEKGELEDRVYVVYV 89
Query: 75 VPLKAL-------AEEKFRE-FKDWERLGLKV-----AMATGDYDSKDEWLGKY---DII 118
PLKAL EE E + E+ G+K+ A+ TGD D+ ++ I+
Sbjct: 90 SPLKALNNDIRKNLEEPLEEIYALAEKKGIKLQKIRAAVRTGDTDAAEKQKQARKPPHIL 149
Query: 119 IATAEKFDSLL--RHGSSWIRDVKMLVIDEIHLIGSRDRGATLEFIITQML----GRAQI 172
I T E +L S + +V+ L++DEIH I RG L + ++ G
Sbjct: 150 ITTPETLAIVLCSPKFSKSLTNVRFLIVDEIHAIAENKRGVHLTLSMERLQRIQEGEMVR 209
Query: 173 IGLSATIGNPEELAEWL-------NAKLIRSD---WRPVKLRKGVFYQGFVFWEDGGSER 222
IGLSATI EE+A +L + +D +P+ ++ V F+ E
Sbjct: 210 IGLSATISPLEEIARFLVGYNYGEERDCVIADVTFEKPMDIK--VVSPINDFFSASAEEI 267
Query: 223 YNSWEELVYDAVKKGKGALVFVNMRRKAEKTALELAKKVKNYLDRKELRELRELAESLEE 282
+ +L+ + VK K L+F N R E+ L K++K++
Sbjct: 268 SDRLYDLLAEYVKSSKTTLIFTNTRSATERVVYHLKKRLKDF------------------ 309
Query: 283 NPTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVI 342
+ HH+ L ++ R+ VE+ + G ++ VV++ +L GI+ ++
Sbjct: 310 -------------PIKAHHSSLSKEVRLEVENELKNGELRCVVSSTSLELGIDIGYIDLV 356
Query: 343 IRDTWRYSEFGMERIPVLEVQQMMGRAGRPRYD-EVGEAIIV 383
I G + + Q +GR+G ++ VG ++V
Sbjct: 357 IL-------LGSPK-SINRALQRIGRSGHRLHEVSVGRIVVV 390
>gb|AAD40191.1| (AF085356) putative RNA helicase [Homo sapiens]
Length = 595
Score = 90.5 bits (221), Expect = 6e-17
Identities = 90/331 (27%), Positives = 146/331 (43%), Gaps = 30/331 (9%)
Query: 230 VYDAVKK---GKGALVFVNMRRKAEKTALELAKKVKNYLDRKELRELRE--LAESLEENP 284
VY A+ K K +VFV R++ TA+++ + R+ E L LE+
Sbjct: 5 VYHAITKYSPKKPVIVFVPSRKQTRLTAIDILTTCAADIQRQRFLHCTEKDLIPYLEKL- 63
Query: 285 TNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIR 344
++ L + LL+GV + H GL ER LVE F G I+VVVA+ +L G+N A VII
Sbjct: 64 SDSTLKETLLNGVGYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIM 123
Query: 345 DTWRYSE--FGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTEEPSLVIDHYIKGKPE 402
DT Y+ P+ +V QM+G A RP D+ G +I+ + D + K E
Sbjct: 124 DTQYYNGKIHAYVDYPIYDVLQMVGHANRPLQDDEGRCVIMCQGSKK----DFFKKFLYE 179
Query: 403 KLFSQLSNESILRSQILALIATFGYSEFKEIYDFLERTF-YAHQGKDPYM---------- 451
L + + + A I T ++ D+L TF Y ++P
Sbjct: 180 PLPVESHLDHCMHDHFNAEIVTKTIENKQDAVDYLTWTFLYRRMTQNPNYYNLQGISHRH 239
Query: 452 ----LEEKIRRIIYFLLENEFIEVTLEDEIKPLPLGVRTTKLYIDPMTAKIFKDTLPRIE 507
L E + + + L +++ I + E ++ PL LG+ YI+ T ++F +L
Sbjct: 240 LSDHLSELVEQTLSDLEQSKCISIEDEMDVAPLNLGMIAAYYYINYTTIELFSMSL---N 296
Query: 508 KNPNPLGIFHMISLAPDLTPLSYSKRETSML 538
G+ +IS A + + E ++L
Sbjct: 297 AKTKVRGLIEIISNAAEYENIPIRHHEDNLL 327
>emb|CAB60375.1| (AL110485) contains similarity to Pfam domain: PF00270 (DEAD/DEAH
box helicase), Score=92.3, E-value=9.4e-29, N=1; PF00646
(F-box domain.), Score=51.8, E-value=5e-12, N=1
[Caenorhabditis elegans]
Length = 1002
Score = 88.5 bits (216), Expect = 2e-16
Identities = 95/328 (28%), Positives = 147/328 (43%), Gaps = 51/328 (15%)
Query: 20 GIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIA----IANKLLEEGG------ 69
G + L Q+ S + E+LL+ PT +GKT + + I N L E+G
Sbjct: 273 GYKSLNRIQSRLCDSALRSKEHLLLCAPTGAGKTNVGLLTMLQEIGNHLAEDGSVKLEEF 332
Query: 70 KAVYIVPLKALAEEKFREF-KDWERLGLKVAMATGDYDSKDEWLGKYDIIIATAEKFDSL 128
K VYI P K+L +E F K G+ V TG +K++++ +I+ T EK+D +
Sbjct: 333 KIVYIAPTKSLVQEMVGSFSKRLAPFGITVGEMTGQM-NKEQFMAT-QVIVCTPEKYDVV 390
Query: 129 LRHGS--SWIRDVKMLVIDEIHLIGSRDRGATLEFIITQMLGRAQIIGLSATIGNPEELA 186
R G ++ + V++L+IDEIHL+ DRG LE I+ R
Sbjct: 391 TRKGGERAYNQMVRLLIIDEIHLLHD-DRGPVLESIVQLFRIRKM--------------- 434
Query: 187 EWLNAK-----LIRSDWRPVKLRKGVFYQGFVFWEDGGSERYNSWEELVYDAVKKGKG-- 239
W + K + +RPV L++ + V ++ S + E VYD + K G
Sbjct: 435 -WRHVKTEHLHFFDNSYRPVPLKQQII---GVTEKNDDSATSQAMNEAVYDKIMKHAGKS 490
Query: 240 -ALVFVNMRRKAEKTALEL--AKKVKNYLD--RKELRELRELAESLEENPTNEKLAKALL 294
LVFV+ R++ +TA + A K+ L +E E+ + E N L L
Sbjct: 491 QVLVFVHYRKETTETAKAIRDACLEKDTLSAFMREGSASTEILRTEAEQAKNLDLKDLLP 550
Query: 295 SGVAFHHAGLGR----DERVLVEDNFRK 318
G A H+AG+ R D+ L+E RK
Sbjct: 551 YGFAIHNAGMNRPQKDDKEKLLETQERK 578
>emb|CAA11251.1| (AJ223310) helicase [Streptomyces avermitilis]
>gi|4098452|gb|AAD00270.1| (U77894) helicase-like
protein [Streptomyces avermitilis]
Length = 612
Score = 87.8 bits (214), Expect = 4e-16
Identities = 61/201 (30%), Positives = 99/201 (48%), Gaps = 22/201 (10%)
Query: 34 SGVLEGENLLVAIPTASGKTLIAEIAIANKLLEEGGKAVYIVPLKALAEEKFREFKDWER 93
SG G+ T SGKT++ E A+ + L++G K Y P+KAL+ +K+ + R
Sbjct: 44 SGTRGGQGGAGGRATGSGKTIVGEFAV-HLALQQGKKCFYTTPIKALSNQKYADLA--RR 100
Query: 94 LGL-KVAMATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSSWIRDVKMLVIDEIHLIGS 152
G KV + TGD + +++ T E ++L GS + + +V+DE+H +
Sbjct: 101 YGADKVGLLTGDNSVNSD----APVVVMTTEVLRNMLYAGSQTLLGLGYVVMDEVHYLSD 156
Query: 153 RDRGATLEFIITQMLGRAQIIGLSATIGNPEELAEWL-----NAKLIRSDWRPVKLRKGV 207
R RGA E +I + ++ LSAT+ N EE +WL + ++I S+ RPV L + V
Sbjct: 157 RFRGAVWEEVIIHLPESVTLVSLSATVSNAEEFGDWLDTVRGDTQVIVSEHRPVPLFQHV 216
Query: 208 FYQGFVFWEDGGSERYNSWEE 228
G Y+ +EE
Sbjct: 217 L---------AGRRMYDLFEE 228
>pir||A56003 nucleolar protein SKI2 homolog - human
Length = 729
Score = 85.8 bits (209), Expect = 1e-15
Identities = 59/175 (33%), Positives = 92/175 (51%), Gaps = 14/175 (8%)
Query: 40 ENLLVAIPTASGKTLIAEIAIANKLLEEGGKAVYIVPLKALAEEKFREFKDWERLGLKVA 99
+++ VA T++GKT++AE AIA + + +Y P+KAL +KFR+F++ G V
Sbjct: 97 DSVFVAAHTSAGKTVVAEYAIA-LAQKHMTRTIYTSPIKALTNQKFRDFRN--TFG-DVG 152
Query: 100 MATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSSWIRDVKMLVIDEIHLIGSRDRGATL 159
+ TGD E +I T E S+L GS IRD++ ++ DE+H I +RG
Sbjct: 153 LLTGDVQLHPE----ASCLIMTTEILRSMLYSGSDVIRDLEWVIFDEVHYINDVERGVVW 208
Query: 160 EFIITQMLGRAQIIGLSATIGNPEELAEWL------NAKLIRSDWRPVKLRKGVF 208
E ++ + II LSAT+ N E A+W+ +I + RPV L +F
Sbjct: 209 EEVLIMLPDHVSIILLSATVPNALEFADWIGRLKRRQIYVISTVTRPVPLEHYLF 263
>pir||F83237 probable ATP-dependent DNA helicase PA3272 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9949397|gb|AAG06660.1|AE004749_9 (AE004749) probable
ATP-dependent DNA helicase [Pseudomonas aeruginosa]
Length = 1448
Score = 82.7 bits (201), Expect = 1e-14
Identities = 106/365 (29%), Positives = 149/365 (40%), Gaps = 85/365 (23%)
Query: 18 ERGIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLEEGGKA------ 71
ER P Q EA + + EG + LVA PT SGKTL A +A + L+ EG A
Sbjct: 30 ERHFAAPTPAQVEAWPA-IREGLSTLVAAPTGSGKTLTAFLAAIDALVVEGLAAGGELAD 88
Query: 72 ----VYIVPLKALAEE----------KFREFKDWERLGL-----KVAMATGDYDSKDEWL 112
VY+ PLKAL+ + RE + RLGL + A+ TGD +
Sbjct: 89 ATQVVYVSPLKALSNDIRINLEQPLAGIRE--ELARLGLPDVDIRSAVRTGDTPQVERGA 146
Query: 113 GKY---DIIIATAEKFDSLL--RHGSSWIRDVKMLVIDEIHLIGSRDRGATLEFIITQML 167
+ I++ T E LL G + V+ +++DEIH + RG+ L + ++
Sbjct: 147 MRKRPPHILVTTPESLYILLGSESGRQMLAGVRSVIVDEIHALAGSKRGSHLALSLERLQ 206
Query: 168 GRAQI----IGLSATIGNPEELAEWLNAKLIRSDWRPVKLRKGVFYQGFVFWEDGGSE-- 221
IGLSAT E++A +L + + P + G+ D G E
Sbjct: 207 ALCPRPLLRIGLSATQKPIEKVARFL----VGASGNPRDPACRIVDVGYTRPRDLGIEVP 262
Query: 222 -------RYNSWEELVYDAVKKGKG----ALVFVNMRRKAEKTALELAKKVKNYLDRKEL 270
N ELVYD + G LVFVN RR AE+
Sbjct: 263 PVALEAVMSNDTWELVYDRLAHLAGEHRTTLVFVNTRRMAERVT---------------- 306
Query: 271 RELRELAESLEENPTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTL 330
R LAE L VA HH L ++ R+ E + G +KV+VAT +L
Sbjct: 307 ---RFLAERLGSRQ------------VAAHHGSLAKELRLDAEQRLKAGQLKVLVATASL 351
Query: 331 SAGIN 335
GI+
Sbjct: 352 ELGID 356
>gb|AAB61106.1| (AC002062) Similar to Synechocystis antiviral protein (gb|D90917).
[Arabidopsis thaliana]
Length = 1198
Score = 74.9 bits (181), Expect = 3e-12
Identities = 55/140 (39%), Positives = 73/140 (51%), Gaps = 19/140 (13%)
Query: 251 EKTALELAKKVKNYLDRKELRELRELAESLEENPTNEKLAKALLSGVAFHHAGLGRDERV 310
EK+ +ELA K L +RE E K LL G+A HHAG +
Sbjct: 494 EKSEVELALKKFRVLYPDAVRESAE---------------KGLLRGIAAHHAGCLPLWKS 538
Query: 311 LVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWRYSEFGMERIPV--LEVQQMMGR 368
+E+ F++GL+KVV AT TL+AGIN PA +I + + G ERI + E+ QM GR
Sbjct: 539 FIEELFQRGLVKVVFATETLAAGINMPARTAVISSLSK--KAGNERIELGPNELYQMAGR 596
Query: 369 AGRPRYDEVGEAIIVSTTEE 388
AGR DE G ++V T E
Sbjct: 597 AGRRGIDEKGYTVLVQTAFE 616
>pir||T50247 probable helicase [imported] - fission yeast (Schizosaccharomyces
pombe) >gi|6901197|emb|CAB71840.1| (AL138666) putative
helicase [Schizosaccharomyces pombe]
Length = 1717
Score = 74.9 bits (181), Expect = 3e-12
Identities = 65/223 (29%), Positives = 105/223 (46%), Gaps = 33/223 (14%)
Query: 26 PPQAEALTSGVLE-GENLLVAIPTASGKTLIAEIAIANKLLE-EGGKAVYIVPLKAL--- 80
P + + T +L+ E++ V PT+SGKT I+ A+ L + + G +Y+ P KAL
Sbjct: 736 PDEWQRETLDILDRDESVFVVAPTSSGKTFISFYAMEKVLRDNDDGVVIYVAPTKALVNQ 795
Query: 81 --AEEKFREFKDWERLGLKV-AMATGDYDSKDEWLGKYDIIIATAEKFDSLLRH---GSS 134
AE R K + G V ++ T DY + ++I S+L ++
Sbjct: 796 LSAEVYARFNKHYPHAGQTVWSVYTRDYRINNPT--NCQVLITVPHVLQSMLLQPALANA 853
Query: 135 WIRDVKMLVIDEIHLIGSRDRGATLEFIITQMLGRAQIIGLSATIGNPEELAEWLNA--- 191
W ++ ++ DEIH IG + G E ++ +L I+ LSAT+GNP+E WL+A
Sbjct: 854 WCPKIRRIIFDEIHCIGQMEDGLVEEQLL--LLAPCPIVALSATVGNPQEFQVWLSALQR 911
Query: 192 ------KLIRSDWRPVKLRKGVFYQGFVFWEDGGSERYNSWEE 228
LI + R LRK V+ GG++ +N +E
Sbjct: 912 AHSYPIHLIVHEHRYSDLRKFVY---------GGAKEFNGLQE 945
>pir||T38420 probable dna helicases - fission yeast (Schizosaccharomyces pombe)
(fragment) >gi|2656007|emb|CAB16187.1| (Z99126)
DEAD/DEAH box helicase [Schizosaccharomyces pombe]
Length = 643
Score = 74.5 bits (180), Expect = 4e-12
Identities = 90/375 (24%), Positives = 159/375 (42%), Gaps = 66/375 (17%)
Query: 10 EKIKEILRERGIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLEEG- 68
E I + R IE+ Y QA+A+ + G +++V+ T+SGK+LI +I I LLE+
Sbjct: 298 ELINALYTSRNIEKTYKHQADAINH-LWNGFHVIVSTSTSSGKSLIYQIPILQSLLEDNQ 356
Query: 69 GKAVYIVPLKALAEEKFREFKDWERL-----GLKVAMATGD--YDSKDEWLGKYDIIIAT 121
A ++ P K+LA+++ + D ++V GD +S++ + +II
Sbjct: 357 STAFFVFPTKSLAQDQKKSLIDILSYMPTLKNIRVDTFDGDTPLESRESIIRSANIIFTN 416
Query: 122 AEKF-DSLLRHGSSW---IRDVKMLVIDEIHLIGSRDRGATLEFIITQMLGRAQIIG--- 174
+ ++L + + W +++K+ V+DE H+ G + F++ +M A+ G
Sbjct: 417 PDMLHQTILPNANRWYYFFKNLKLFVLDEAHVYNGIF-GVHVAFVLRRMRRIAEYFGNSQ 475
Query: 175 -----LSATIGNPEELAEWL----NAKLIRSDWRPVKLRKGVFYQGFVFW---------- 215
SATI +P + + + N KLI P +K FV W
Sbjct: 476 YRFVSCSATIEDPLQHMKKIFGVDNIKLINYTSSPSGSKK------FVMWNPPYVDPKHP 529
Query: 216 EDGGSERYNSWEELVYDAVKKGKGALVFVNMRRKAEKTALELAKKVKNYLDRKELRELRE 275
+DG + +L+ +K +VF +R KT L + V+ L K+ +L
Sbjct: 530 DDGKKSAISEASKLLIKFAEKRVRTIVFCRVR----KTCESLMRLVRQELKTKQKGDL-- 583
Query: 276 LAESLEENPTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGIN 335
LS + + AG ER +E G + ++AT L GI+
Sbjct: 584 ------------------LSKIQSYRAGYTVQERRKIESEMFNGKLYGIIATNALELGID 625
Query: 336 TPAFRVIIRDTWRYS 350
+ +I + YS
Sbjct: 626 IGSLDAVITIGFPYS 640
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.319 0.139 0.395
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 262649458
Number of Sequences: 2977
Number of extensions: 11382006
Number of successful extensions: 32233
Number of sequences better than 1.0e-10: 104
Number of HSP's better than 0.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 87
Number of HSP's that attempted gapping in prelim test: 31666
Number of HSP's gapped (non-prelim): 190
length of query: 715
length of database: 189,106,746
effective HSP length: 59
effective length of query: 656
effective length of database: 153,796,013
effective search space: 100890184528
effective search space used: 100890184528
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 168 (69.9 bits)