BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB0609 (putP-1) DE:OSMOREGULATED PROLINE TRANSPORTER
         (484 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||E75138 osmoregulated proline transporter PAB0609 - Pyrococc...   957  0.0
sp|O06493|OPUE_BACSU OSMOREGULATED PROLINE TRANSPORTER (SODIUM/P...   261  1e-68
emb|CAA70363.1| (Y09163) proline transport system [Corynebacteri...   261  1e-68
pir||C71008 probable proline permease - Pyrococcus horikoshii >g...   257  1e-67
pir||A75123 proline permease (putp-2) PAB1841 - Pyrococcus abyss...   255  1e-66
pir||H82382 sodium/proline symporter VCA1071 [imported] - Vibrio...   255  1e-66
pir||T44298 proline transporter [imported] - Bacillus halodurans...   252  6e-66
pir||D75188 proline symporter (proline permease). PAB2354 - Pyro...   248  1e-64
pir||B69759 sodium/proline symporter ycgO - Bacillus subtilis >g...   238  8e-62
gb|AAA79365.1| (U06451) proline permease homolog [Staphylococcus...   234  2e-60
pir||T48676 proline uptake protein [validated] - Staphylococcus ...   231  2e-59
pir||B81297 sodium/proline symporter Cj1502c [imported] - Campyl...   229  7e-59
pir||G81202 sodium/proline symporter NMB0402 [imported] - Neisse...   228  9e-59
pir||JC2382 sodium/proline symporter - Pseudomonas fluorescens >...   228  1e-58
pir||F83547 sodium/proline symporter PutP PA0783 [imported] - Ps...   227  2e-58
pir||A71980 sodium/proline symporter - Helicobacter pylori (stra...   226  4e-58
pir||G64526 sodium/proline symporter - Helicobacter pylori (stra...   224  1e-57
pir||S10220 sodium/proline symporter - Salmonella typhimurium         224  2e-57
gb|AAA24461.1| (L01132) proline permease [Escherichia coli] >gi|...   223  4e-57
sp|P07117|PUTP_ECOLI SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE)...   222  5e-57
sp|P10502|PUTP_SALTY SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE)...   222  5e-57
gb|AAA99288.1| (L01146) proline permease [Salmonella sp.] >gi|15...   222  5e-57
gb|AAA24463.1| (L01150) proline permease [Escherichia coli] >gi|...   222  5e-57
gb|AAA27199.1| (L01135) proline permease [Salmonella typhimurium]     222  5e-57
gb|AAA26389.1| (L01134) proline permease [Rickettsia typhi]           222  5e-57
gb|AAA99282.1| (L01140) proline permease [Salmonella sp.] >gi|15...   222  5e-57
gb|AAA24466.1| (L01153) proline permease [Escherichia coli] >gi|...   222  5e-57
gb|AAA24462.1| (L01133) proline permease [Escherichia coli]           222  7e-57
gb|AAA24468.1| (L01155) proline permease [Escherichia coli]           222  7e-57
gb|AAA99290.1| (L01148) proline permease [Salmonella sp.]             222  9e-57
gb|AAA99291.1| (L01149) proline permease [Salmonella sp.]             222  9e-57
gb|AAA99278.1| (L01136) proline permease [Salmonella sp.]             221  1e-56
gb|AAA99279.1| (L01137) proline permease [Salmonella sp.]             221  1e-56
gb|AAA24465.1| (L01152) proline permease [Escherichia coli]           221  2e-56
gb|AAA99281.1| (L01139) proline permease [Salmonella sp.]             221  2e-56
gb|AAA99280.1| (L01138) proline permease [Salmonella sp.]             220  2e-56
gb|AAA99284.1| (L01142) proline permease [Salmonella sp.] >gi|15...   220  2e-56
gb|AAA99286.1| (L01144) proline permease [Salmonella sp.] >gi|15...   220  2e-56
gb|AAF25001.1|AF153207_2 (AF153207) proline permease [Pseudomona...   215  7e-55
gb|AAG19342.1| (AE005029) proline permease; PutP [Halobacterium ...   210  2e-53
dbj|BAB06425.1| (AP001516) proline transporter [Bacillus halodur...   208  9e-53
sp|P45174|PUTP_HAEIN SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE)...   207  2e-52
gi|11498674 pantothenate permease (panF-1) [Archaeoglobus fulgid...   170  4e-41
sp|P44963|PANF_HAEIN SODIUM/PANTOTHENATE SYMPORTER (PANTOTHENATE...   152  1e-35
pir||D65118 pantothenate permease [validated] - Escherichia coli...   144  2e-33
sp|P16256|PANF_ECOLI SODIUM/PANTOTHENATE SYMPORTER (PANTOTHENATE...   143  4e-33
pir||C69115 sodium/proline symporter (proline permease) - Methan...   137  3e-31
gb|AAF45280.1| (AF230619) proline permease [Escherichia coli]         135  1e-30
gb|AAF45283.1| (AF230622) proline permease [Escherichia coli]         132  6e-30
gb|AAF45263.1| (AF230602) proline permease [Escherichia coli] >g...   132  8e-30
gb|AAF45264.1| (AF230603) proline permease [Escherichia coli] >g...   132  8e-30
gb|AAF45285.1| (AF230624) proline permease [Escherichia coli]         132  8e-30
gb|AAF45286.1| (AF230625) proline permease [Escherichia coli]         130  4e-29
pir||E70201 pantothenate permease (panF) homolog - Lyme disease ...   127  2e-28
sp|P39599|YWCA_BACSU HYPOTHETICAL 55.0 KD PROTEIN IN EPR-GALK IN...   120  3e-26
pir||JU0296 pantothenate permease - Escherichia coli >gi|147067|...   118  2e-25
pir||F83241 probable sodium:solute symporter PA3234 [imported] -...   117  2e-25
emb|CAB59438.1| (AL132644) putative transmembrane transport prot...   117  3e-25
sp|P32705|YJCG_ECOLI HYPOTHETICAL 59.2 KD PROTEIN IN SOXR-ACS IN...   111  2e-23
dbj|BAB07462.1| (AP001519) Na+/solute symporter (Ssf family) [Ba...   109  5e-23
gi|11498574 proline permease (putP-2) [Archaeoglobus fulgidus] >...   105  1e-21
pir||C82582 Na+-dependent symport homolog XF2251 [imported] - Xy...   104  2e-21
pir||H75513 probable sodium/proline symporter DR0477 [similarity...   102  9e-21
gi|11497853 pantothenate permease (panF-3) [Archaeoglobus fulgid...   102  1e-20
gi|11497636 proline permease (putP-1) [Archaeoglobus fulgidus] >...   101  2e-20
pir||G83610 probable sodium:solute symporter PA0287 [imported] -...   101  2e-20
emb|CAA94864.1| (Z71176) phenylacetic acid permease [Pseudomonas...   101  3e-20
pir||E83468 probable sodium:solute symport protein PA1418 [impor...   101  3e-20
pir||S75887 hypothetical protein - Synechocystis sp. (strain PCC...   100  3e-20
pir||H71097 hypothetical protein PH1044 - Pyrococcus horikoshii ...    99  1e-19
gi|11498821 proline permease (putP-3) [Archaeoglobus fulgidus] >...    98  2e-19
gb|AAG20007.1| (AE005081) pantothenate permease; PanF [Halobacte...    98  2e-19
pir||T03475 transmembrane protein - Rhodobacter capsulatus >gi|3...    97  4e-19
gi|4507035 solute carrier family 5 (sodium iodide symporter), me...    96  7e-19
gi|11498804 pantothenate permease (panF-2) [Archaeoglobus fulgid...    96  9e-19
dbj|BAA24835.1| (D87920) sodium iodide symporter [Homo sapiens]        96  9e-19
emb|CAB88444.1| (AL353815) putative sodium-coupled permease [Str...    95  2e-18
emb|CAC17810.1| (AJ276242) sodium iodide symporter [Sus scrofa]        95  2e-18
emb|CAC17816.1| (AJ276292) sodium iodide symporter [Sus scrofa]        95  2e-18
gi|11141885 solute carrier family 5 (choline transporter), membe...    92  1e-17
sp|P96169|SGLT_VIBPA SODIUM/GLUCOSE COTRANSPORTER (NA(+)/GLUCOSE...    92  1e-17
dbj|BAA11215.1| (D78137) Na+/glucose symporter [Vibrio parahaemo...    92  2e-17
gi|11528510 solute carrier family 5 (choline transporter), membe...    92  2e-17
gb|AAG36945.1| (AF276872) sodium and chloride-dependent high-aff...    91  2e-17
dbj|BAA90483.1| (AB030946) high-affinity choline transporter CHO...    91  3e-17
dbj|BAA90484.1| (AB030947) high-affinity choline transporter CHT...    90  4e-17
emb|CAB95932.1| (AL359989) putative sodium:solute symporter [Str...    88  3e-16
prf||2204393A Na/I symporter [Rattus norvegicus]                       87  6e-16
gi|10863879 solute carrier family 5 (sodium-dependent vitamin tr...    87  6e-16
gi|11429441 solute carrier family 5 (sodium-dependent vitamin tr...    87  6e-16
gb|AAC12270.1| (AF026554) sodium-dependent multi-vitamin transpo...    86  8e-16
pir||S68513 thyroid iodide transport protein - rat >gi|1399954|g...    86  1e-15
gb|AAD37480.1|AF080067_1 (AF080067) sodium-dependent multi-vitam...    85  2e-15
pir||T35201 probable transmembrane transport - Streptomyces coel...    84  4e-15
pir||D72694 hypothetical protein APE0972 - Aeropyrum pernix (str...    83  5e-15
dbj|BAB05941.1| (AP001514) Na+/myo-inositol cotransporter [Bacil...    82  1e-14
sp|P23723|PUTP_KLEPN SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE)...    81  3e-14
emb|CAC16517.1| (AL450223) putative integral membrane transport ...    80  6e-14
pir||S52839 dhlC protein - Xanthobacter autotrophicus >gi|763398...    79  1e-13
gb|AAF17249.1|AF208031_1 (AF208031) SGLT1 protein [Mus musculus]       77  5e-13
pir||S48857 glucose transport protein - sheep >gi|2148056|pir||S...    77  5e-13
sp|P53791|SL51_SHEEP SODIUM/GLUCOSE COTRANSPORTER 1 (NA(+)/GLUCO...    76  6e-13
sp|P31448|YIDK_ECOLI HYPOTHETICAL 62.1 KD PROTEIN IN EMRD-GLVG I...    76  8e-13
pir||S48858 glucose transport protein homolog - sheep                  76  1e-12

>pir||E75138 osmoregulated proline transporter PAB0609 - Pyrococcus abyssi
           (strain Orsay) >gi|5458333|emb|CAB49822.1| (AJ248285)
           OSMOREGULATED PROLINE TRANSPORTER [Pyrococcus abyssi]
           Length = 484
           
 Score =  957 bits (2448), Expect = 0.0
 Identities = 484/484 (100%), Positives = 484/484 (100%)

Query: 1   MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60
           MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC
Sbjct: 1   MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60

Query: 61  LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEA 120
           LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEA
Sbjct: 61  LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEA 120

Query: 121 EKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLK 180
           EKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLK
Sbjct: 121 EKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLK 180

Query: 181 SVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGA 240
           SVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGA
Sbjct: 181 SVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGA 240

Query: 241 AAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGWI 300
           AAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGWI
Sbjct: 241 AAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGWI 300

Query: 301 GIAIFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSENI 360
           GIAIFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSENI
Sbjct: 301 GIAIFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSENI 360

Query: 361 LKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVI 420
           LKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVI
Sbjct: 361 LKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVI 420

Query: 421 VILTLFWKRFHGKAVPPTIIAGLLFTVFWISSGLDAKVSVRLMNFIVTFIVAIIATYAIK 480
           VILTLFWKRFHGKAVPPTIIAGLLFTVFWISSGLDAKVSVRLMNFIVTFIVAIIATYAIK
Sbjct: 421 VILTLFWKRFHGKAVPPTIIAGLLFTVFWISSGLDAKVSVRLMNFIVTFIVAIIATYAIK 480

Query: 481 PEKT 484
           PEKT
Sbjct: 481 PEKT 484


>sp|O06493|OPUE_BACSU OSMOREGULATED PROLINE TRANSPORTER (SODIUM/PROLINE SYMPORTER)
           >gi|7442757|pir||H69670 sodium/proline symporter opuE -
           Bacillus subtilis >gi|2114423|gb|AAB66512.1| (U92466)
           osmoregulated proline transporter [Bacillus subtilis]
           >gi|2465556|gb|AAB72182.1| (AF011545) OpuE [Bacillus
           subtilis] >gi|2632980|emb|CAB12486.1| (Z99107) proline
           transporter [Bacillus subtilis]
           Length = 492
           
 Score =  261 bits (660), Expect = 1e-68
 Identities = 147/479 (30%), Positives = 259/479 (53%), Gaps = 18/479 (3%)

Query: 7   ILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPG 66
           I+++ ++++  L+ +G Y  +K     D+ + GR L  +V ALS  A   S W L+G+PG
Sbjct: 6   IISLGIYFIAMLL-IGWYAFKKTTDINDYMLGGRGLGPFVTALSAGAADMSGWMLMGVPG 64

Query: 67  FAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKY-DAVTFVDYIAKRHPEAEKWIR 125
             FA GL+ +W A+G  +G    + + A RLR   E   DA+T  D+  KR   +   ++
Sbjct: 65  AMFATGLSTLWLALGLTIGAYSNYLLLAPRLRAYTEAADDAITIPDFFDKRFQHSSSLLK 124

Query: 126 ILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYT 185
           I+ +  I  FF  Y  +  + GG++  + FG D KLG+ +T  V++ YT+ GG  +V+ T
Sbjct: 125 IVSALIIMIFFTLYTSSGMVSGGRLFESAFGADYKLGLFLTTAVVVLYTLFGGFLAVSLT 184

Query: 186 DTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAAIVF 245
           D VQ  +M   L++ PIV   ++          V     +       +L    G A+++ 
Sbjct: 185 DFVQGAIMFAALVLVPIVAFTHVG--------GVAPTFHEIDAVNPHLLDIFKG-ASVIS 235

Query: 246 VIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGWIGIAIF 305
           +I+  +W  GY  G P + +RFMAIKD K+ K AR IG+ W II  +G+++ G IG+A  
Sbjct: 236 IISYLAWGLGYY-GQPHIIVRFMAIKDIKDLKPARRIGMSWMIITVLGSVLTGLIGVAYA 294

Query: 306 GPNG--LKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSENILKP 363
              G  +KDPE +       LF P +    ++  +AA++S+  S L+++++  +E++ + 
Sbjct: 295 HKFGVAVKDPEMIFIIFSKILFHPLITGFLLSAILAAIMSSISSQLLVTASAVTEDLYRS 354

Query: 364 YIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVIVIL 423
           + ++ +A  ++ +M+ RL+ + + +IA++++ + P+  I  +VGY WAG G  F   ++L
Sbjct: 355 F-FRRKASDKELVMIGRLSVLVIAVIAVLLS-LNPNSTILDLVGYAWAGFGSAFGPAILL 412

Query: 424 TLFWKRFHGKAVPPTIIAGLLFTVFWISSGLDAKVSVR--LMNFIVTFIVAIIATYAIK 480
           +L+WKR +       +I G    + WI++GL     V   +  FI++ I  II +   K
Sbjct: 413 SLYWKRMNEWGALAAMIVGAATVLIWITTGLAKSTGVYEIIPGFILSMIAGIIVSMITK 471


>emb|CAA70363.1| (Y09163) proline transport system [Corynebacterium glutamicum]
           Length = 524
           
 Score =  261 bits (660), Expect = 1e-68
 Identities = 155/492 (31%), Positives = 252/492 (50%), Gaps = 19/492 (3%)

Query: 1   MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60
           M   T  +  +V Y+  ++ +G +  RK + + D+ +AGR L  +VAA+S  A+  S W 
Sbjct: 1   MSDNTWFIIAIVIYMLVMVLIGYWSYRKTEKYDDYMLAGRGLNPFVAAMSAGASDMSGWL 60

Query: 61  LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119
           L+GLPG  F  G++ +W A+G  +G    W   A RLR  +E   +++T   +   R  +
Sbjct: 61  LMGLPGALFVTGMSELWIAVGLTIGAWANWMWVAPRLRSYSEISANSITLPSFFENRLRD 120

Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179
             + +RI+ +  I  FF FY+ +  + GG    + FG D  LGM I A V + YT +GG 
Sbjct: 121 KSRALRIIAALIIIVFFTFYISSGMVAGGVYWESTFGGDYLLGMAIVAGVTVLYTFIGGF 180

Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPEL--YATSVTAALSKAGV---KYSTIL 234
            +V+YTD VQ  +M  +LI+ P++    +AN  ++  +A S        G+    Y +++
Sbjct: 181 LAVSYTDAVQGTIMFFSLIIVPVMAYFALANPMDIWSFANSNDYGPHTDGIGNPTYFSMI 240

Query: 235 GGMAGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGA 294
            G++ AA    +I    W  GY  G P + +RFMA++    AK  R IGI W II  IGA
Sbjct: 241 SGISAAA----IIGNLGWGLGYF-GQPHIVVRFMALRTPAEAKQGRRIGISWMIICLIGA 295

Query: 295 LMIGWIGIAIFGPN------GLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSL 348
                I    F  N        +  E +   +   LF P +A + +T  +AA++ST  S 
Sbjct: 296 TFTAIISTVFFAQNPDANITDTRAYESIFLDLARMLFHPLIAGLILTAVLAAIMSTMSSQ 355

Query: 349 LILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGY 408
           L+++++   E++LK  + K+    R  +M+SR T + L IIA  MA + PS  I  +VG+
Sbjct: 356 LLVTASSLIEDLLK-VVKKDSLSERTLIMLSRATVIILAIIAAAMA-INPSDSILGLVGF 413

Query: 409 TWAGIGDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSGLDAKVSVRLMNFIVT 468
            WAG G  F  I++ +L+WKR +       +I G + ++ W  S L   +   +  F + 
Sbjct: 414 AWAGFGSAFGPIILASLYWKRLNAAGAISGMITGAIVSIAWGMSPLSDTLYEIIPGFALA 473

Query: 469 FIVAIIATYAIK 480
            IV ++ +   K
Sbjct: 474 TIVMVVVSLLTK 485


>pir||C71008 probable proline permease - Pyrococcus horikoshii
           >gi|3257784|dbj|BAA30467.1| (AP000006) 537aa long
           hypothetical proline permease [Pyrococcus horikoshii]
           Length = 537
           
 Score =  257 bits (651), Expect = 1e-67
 Identities = 165/501 (32%), Positives = 259/501 (50%), Gaps = 39/501 (7%)

Query: 7   ILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPG 66
           IL   + YL  L  +G +  R  K+ + + I GR++    A LS++A+  S W +LG PG
Sbjct: 5   ILLGFLIYLVLLAYIGWWANRYTKTEEQYFIGGRKVHVLAATLSDKASDFSGWLMLGYPG 64

Query: 67  FAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRI 126
            AF  GL A W AIGC+ G +  + +   RLR  A K+ ++T  DY+  R  +  K IRI
Sbjct: 65  TAFKTGLGAFWAAIGCLFGTLADYLLIGPRLRIYAGKFRSITLPDYLEARLKDNTKLIRI 124

Query: 127 LGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTD 186
           L +A I  F   YV AQ+  GGK  +  FG+    G+LIT +++  Y + GG  +V +TD
Sbjct: 125 LSAAIILIFMTAYVAAQFAAGGKTFSEAFGVSVTTGILITVIILTAYVITGGFFAVVWTD 184

Query: 187 TVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAAIVFV 246
            VQA+ M+LTLI+ PI+ +  I    +  AT +  +++ A +      GG  G AAIVF 
Sbjct: 185 VVQAMFMLLTLIIMPILALAEIGGLDK--ATQIIGSVNPAKLH---PFGGATGLAAIVFA 239

Query: 247 IAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIG-WTIIAYIGALMIGWIG--IA 303
           I   SW  GYL G P +  R+M+++D +  +       G WT I   GA   G++G  +A
Sbjct: 240 IGYASWIVGYL-GQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALA 298

Query: 304 IFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSENILKP 363
           I G   + DPE+++P++ +   P  +A   I G ++A++STADS L+++S+  + +I   
Sbjct: 299 INGSIKIDDPEKIVPAMAVHFLPSWIAGFVIAGIISAVMSTADSQLLVASSAIARDIYHK 358

Query: 364 YIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVIVIL 423
            +   E   ++ + +SR+    + +IA+  A   P  +IY +V   W G+   F  I+ L
Sbjct: 359 -VLGQELGKKQMVNISRVVVAIVSLIAMWFAISGPK-VIYQMVATAWGGLAVGFGPILTL 416

Query: 424 TLFWKRFHGKAVPPTIIAGLLFTVFWISSGLDAK-----------------------VSV 460
           +L+WKR   +A    +  GL+  V      L+AK                       V V
Sbjct: 417 SLWWKRVTKEAGIIGMGYGLISEVL-----LEAKIYGWAFNPNAPGFFGTLGKWFNGVPV 471

Query: 461 RLMNFIVTFIVAIIATYAIKP 481
             +NF +T +V II +   KP
Sbjct: 472 FFINFFITLLVIIIVSLLTKP 492


>pir||A75123 proline permease (putp-2) PAB1841 - Pyrococcus abyssi  (strain
           Orsay) >gi|5458209|emb|CAB49698.1| (AJ248285) proline
           permease (putP-2) [Pyrococcus abyssi]
           Length = 537
           
 Score =  255 bits (644), Expect = 1e-66
 Identities = 161/501 (32%), Positives = 254/501 (50%), Gaps = 39/501 (7%)

Query: 7   ILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPG 66
           IL   + YL  L  +G +  +  K+   + + GR++    A LS++A+  S W +LG PG
Sbjct: 5   ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64

Query: 67  FAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRI 126
            AF AGL A W  IGC+ G +  + +   RLR  A K+ A+T  DY+  R  +  K IRI
Sbjct: 65  SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRI 124

Query: 127 LGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTD 186
           L +A I  F   YV AQ+  GGK     F +    G+LIT +++  Y + GG  +V +TD
Sbjct: 125 LSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTD 184

Query: 187 TVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAAIVFV 246
            VQA+ M+LTLI+ PI+ ++ I       AT + A++    +      GG  G AAIVF 
Sbjct: 185 VVQAMFMLLTLIIMPILALVEIGGLDR--ATQIIASVDPNKLH---PFGGATGWAAIVFA 239

Query: 247 IAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIG-WTIIAYIGALMIGWIGIAIF 305
           I   SW  GYL G P +  R+M+++D +  +       G WT I   GA   G++G A+ 
Sbjct: 240 IGYASWIVGYL-GQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALV 298

Query: 306 GPNGLK--DPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSENILKP 363
               +K  DPE+++P++ +   P  +A   I G ++A++STADS L+++S+  + +I   
Sbjct: 299 ASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHK 358

Query: 364 YIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVIVIL 423
            +   E   ++ + +SR+   ++ ++A+  A   P  +IY +V   W G+   F  I+ L
Sbjct: 359 -VLGQELGKKQMVNISRIVVAAVALVAMWFAITGPK-VIYQMVATAWGGLAVGFGPILTL 416

Query: 424 TLFWKRFHGKAVPPTIIAGLLFTVFWISSGLDAK-----------------------VSV 460
           +L+WKR   +A    +  GL+  V      L+AK                       V V
Sbjct: 417 SLWWKRVTKEAGIVGMAYGLISEVI-----LEAKIYGWAFNPKAPGFFGTLGQWFNGVPV 471

Query: 461 RLMNFIVTFIVAIIATYAIKP 481
             +NF VT  + II +   KP
Sbjct: 472 FFINFFVTLFIIIIVSLLTKP 492


>pir||H82382 sodium/proline symporter VCA1071 [imported] - Vibrio cholerae
           (group O1 strain N16961) >gi|9658517|gb|AAF96965.1|
           (AE004432) sodium/proline symporter [Vibrio cholerae]
           Length = 496
           
 Score =  255 bits (644), Expect = 1e-66
 Identities = 145/455 (31%), Positives = 243/455 (52%), Gaps = 18/455 (3%)

Query: 1   MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60
           ME    I    + YL  ++++G+Y  ++ K+  D+ + GR L  W AALS  A+  S W 
Sbjct: 1   MENSFAITTTFIVYLILMLAIGVYAYQRTKNSADYFLGGRSLGPWPAALSAGASDMSGWL 60

Query: 61  LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEA 120
           LLGLPG+A+AAG+ + W A G ++G    W V A RLR  +   D++T  +++++R  + 
Sbjct: 61  LLGLPGYAYAAGIESFWLAGGLLVGTWANWLVNAKRLRTYSITTDSLTLPEFLSRRFNDN 120

Query: 121 EKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLK 180
            K I+ + +  I  FF FY  +  + GGK+  T+FGLD    ++I  + ++ YT+ GG  
Sbjct: 121 SKLIQTISAFFILLFFLFYTSSGLVAGGKLFETVFGLDYSTAVIIGTVCVVSYTLFGGFL 180

Query: 181 SVAYTDTVQAIVMILTLIVAPIV---GVIYIANHPELYATSVTAALSKAGVKYSTILGGM 237
           +V++TD VQ ++M   L++ PI    G     NH       + A   +    ++   G  
Sbjct: 181 AVSWTDLVQGLLMAAALMIVPIAAMNGGFTQLNH------DLAAINPELLTLWNDAKGEP 234

Query: 238 AGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMI 297
             A AI+ ++A   W  GY  G P +  RF A + +K+   AR I + WT ++  GA+++
Sbjct: 235 LSAIAIISLVA---WGLGYF-GQPHILARFKASRSNKDLITARRIAVVWTGLSMAGAILV 290

Query: 298 GWIGIAIF---GPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSST 354
           G  G+      G  GL D E++   ++  LF P +A + +   +AA++STADS L++SS+
Sbjct: 291 GLTGLIFVTQSGTIGLDDGEKIFMLLVNSLFHPVIAGILLAAILAAIMSTADSQLLVSSS 350

Query: 355 EFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIG 414
             +E+  K  ++K +A     + V R+  + + +IAL +A + P   +  +V Y WAG G
Sbjct: 351 ALAEDFYK-QVFKTDASSEDIVRVGRIAVILISLIALFLA-MTPDSSVLGLVSYAWAGFG 408

Query: 415 DTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFW 449
             F   ++L+L+W R +       II G +  V W
Sbjct: 409 AAFGPALVLSLYWPRMNRHGALSGIIVGGVTIVVW 443


>pir||T44298 proline transporter [imported] - Bacillus halodurans
           >gi|4512352|dbj|BAA75317.1| (AB011836) proline
           transporter [Bacillus halodurans]
           >gi|10173274|dbj|BAB04379.1| (AP001509) sodium/proline
           symporter [Bacillus halodurans]
           Length = 501
           
 Score =  252 bits (637), Expect = 6e-66
 Identities = 159/493 (32%), Positives = 255/493 (51%), Gaps = 29/493 (5%)

Query: 1   MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60
           ME  T ++  +V+ +G L+ +G+   R   +  D+ + GR+L G VAALS  A+  S+W 
Sbjct: 1   MELAT-LITFIVYLVGMLV-IGLIAYRMTNNLSDYVLGGRRLGGSVAALSAGASDMSSWL 58

Query: 61  LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119
           LLGLPG  +  G+  IW A+G  +G  + W   A RLR   E   D++T  D++  R  +
Sbjct: 59  LLGLPGALYVGGMGEIWIAVGLAIGAYLNWQFLAARLRNYTEIAKDSITLPDFLENRFHD 118

Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179
             K +RI+ +  I  FF FY  A  +GG  +    FG+     + I A+VI+ YT +GG 
Sbjct: 119 KSKILRIVSALVILVFFTFYTSAGLVGGALLFEASFGMTYIQALWIGAIVIISYTFLGGF 178

Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239
            +V++TD  Q I+M L LI+ PIV +  +    E         L+  G   +  L    G
Sbjct: 179 LAVSWTDFFQGILMFLALIIVPIVAINKMGGFSE--------TLNAVGAIDTAYLDAFQG 230

Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299
            A ++ V +  +W  GY  G P +  RFMA+K  K    AR IG+ W ++A  GA+  G+
Sbjct: 231 -ATVIGVASLLAWGLGYF-GQPHIVTRFMAVKSLKEIPKARFIGMTWMVLALFGAIFTGF 288

Query: 300 IGIAIFGPNGLKDPE---QVMPSVMLK----LFPPALAAVFITGAVAAMLSTADSLLILS 352
           +GIA F   G   PE   +   +V +     LF P +A   +   ++A++ST DS L++S
Sbjct: 289 VGIAYFSATG-PGPEIAGEARETVFILFTQILFDPWVAGFLLAAILSAIMSTIDSQLLVS 347

Query: 353 STEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAG 412
           S+  +E+  K  + KN A  ++ + V R   V + ++A+++AY  P   +  +VGY WAG
Sbjct: 348 SSALAEDFYKGMLRKN-ASQKELVWVGRFGVVLIALVAIVLAY-NPDSTVLDLVGYAWAG 405

Query: 413 IGDTFSVIVILTLFWKRF-HGKAVPPTIIAGLLFTVF-----WISSGLDAKVSVRLMNFI 466
            G  F  +++L+LFWKR     A+   ++ G    ++     W +  ++    + L   I
Sbjct: 406 FGAAFGPVLLLSLFWKRMTRNGALAGMVVGGATVIIWAELTNWFNLSVEQYPILGLYEII 465

Query: 467 VTFIVAIIATYAI 479
             FI+A IA   +
Sbjct: 466 PGFILASIAIIVV 478


>pir||D75188 proline symporter (proline permease). PAB2354 - Pyrococcus abyssi
           (strain Orsay) >gi|5457464|emb|CAB48955.1| (AJ248283)
           PROLINE SYMPORTER (PROLINE PERMEASE). [Pyrococcus
           abyssi]
           Length = 492
           
 Score =  248 bits (627), Expect = 1e-64
 Identities = 151/482 (31%), Positives = 251/482 (51%), Gaps = 31/482 (6%)

Query: 8   LAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGF 67
           L   +F L   I VG Y  ++ KS +DF + GR +     ALS  ++G S+W +LGL G 
Sbjct: 14  LVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGM 73

Query: 68  AFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRIL 127
           A+  G+ A+W A+G ++  +  +     RLRK +E+++A+T  DY   R  +  K +RI 
Sbjct: 74  AYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSKILRIA 133

Query: 128 GSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTDT 187
            S  I  F   YVGAQ+  G K L+T  G+     ++I+ L+I+ Y ++GG  +VAY D 
Sbjct: 134 ASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYNDV 193

Query: 188 VQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAAIVFVI 247
           ++A++MI+ L+V P++ V  +    E+    V  AL         ++   A  A +V   
Sbjct: 194 IRAVIMIIGLVVLPVIAVAKVGGTEEV--LKVLHALD------PKLINPWAFGAGVV--- 242

Query: 248 AEFSWFFGYLG------GMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGWIG 301
                  G+LG      G P + +R+M+I D    +++  +G  W ++   GA+ +G  G
Sbjct: 243 ------IGFLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAG 296

Query: 302 IAIFGPNGL---KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSE 358
            AI         K+ E + P +  + FPP L  + I G  AA+LSTADS L++ ++   +
Sbjct: 297 RAIVPDVSQLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVK 356

Query: 359 NILKPYIYK-NEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTF 417
           ++ +  I K  + D + +L +SR+T + +G +A I+AYV    +I+  V + W G+G +F
Sbjct: 357 DLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVA-KDIIFWFVLFAWGGLGASF 415

Query: 418 SVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSGLDAKVSVRLMNFIVTFIVAIIATY 477
              +IL+L+WK      V   +I G + T+ W    L  K    L   +  FI ++IAT 
Sbjct: 416 GPTLILSLYWKGTTKWGVLAGMIVGTITTIVW---KLYLKPITGLYELVPAFIFSLIATI 472

Query: 478 AI 479
            +
Sbjct: 473 IV 474


>pir||B69759 sodium/proline symporter ycgO - Bacillus subtilis
           >gi|1805394|dbj|BAA08956.1| (D50453) homologue of
           proline permease of E. coli [Bacillus subtilis]
           >gi|2632608|emb|CAB12116.1| (Z99105) similar to proline
           permease [Bacillus subtilis]
           Length = 449
           
 Score =  238 bits (602), Expect = 8e-62
 Identities = 142/437 (32%), Positives = 229/437 (51%), Gaps = 19/437 (4%)

Query: 46  VAALSERATGESAWCLLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKY- 104
           V ALS  A   S W L+GLPG  F+ GL+  W  IG  LG    W   A RLR   EK  
Sbjct: 5   VTALSAGAADMSGWLLMGLPGAMFSTGLSGAWIVIGLCLGAWANWLYVAPRLRTYTEKAG 64

Query: 105 DAVTFVDYIAKRHPEAEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGML 164
           +++T   ++  R  +  K +R+     I  FF FYV +  + GG + N++ G+D   G+ 
Sbjct: 65  NSITIPGFLENRFGDQTKLLRLFSGIVILVFFTFYVSSGMVSGGVLFNSILGMDYHTGLW 124

Query: 165 ITALVILPYTVMGGLKSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALS 224
           I   V++ YT+ GG  +V++TD VQ I+M   LI+ PIV   +        A    A + 
Sbjct: 125 IVTGVVVAYTLFGGFLAVSWTDFVQGIIMFAALILVPIVTFFHTGG-----AGDTVAEIR 179

Query: 225 KAGVKYSTILGGMAGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGI 284
                   I  G     +++ +I+ F+W  GY  G P + +RFMAI   K  K AR IG+
Sbjct: 180 SVDPDMFNIFKG----TSVLGIISLFAWGLGYF-GQPHIIVRFMAITSVKEIKRARRIGM 234

Query: 285 GWTIIAYIGALMIGWIGIAIFGPNG--LKDPEQVMPSVMLKLFPPALAAVFITGAVAAML 342
           GW I++ +GA++ G  GIA +   G  LKDPE +   +   LF P +    I+  +AA++
Sbjct: 235 GWMILSAVGAVLTGLGGIAYYHQRGMTLKDPETIFIQLGNILFHPIITGFLISAILAAIM 294

Query: 343 STADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLI 402
           ST  S L+++S+   E++ K  +++  A  ++ + + RL  +++ I+AL++A+   ++ I
Sbjct: 295 STISSQLLVTSSSLVEDLYKS-MFRRSASDKELVFLGRLAVLAVSIVALVLAW-EKNNTI 352

Query: 403 YTIVGYTWAGIGDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSGLDAKVSVRL 462
             +V Y WAG G +F  +V+L+LFWKR         +I G    + W ++GL    S  L
Sbjct: 353 LGLVSYAWAGFGASFGPVVLLSLFWKRMTKWGALAGMIVGAATVIIWANAGL----SDFL 408

Query: 463 MNFIVTFIVAIIATYAI 479
              I  F  ++++ + +
Sbjct: 409 YEMIPGFAASLLSVFFV 425


>gb|AAA79365.1| (U06451) proline permease homolog [Staphylococcus aureus]
           Length = 497
           
 Score =  234 bits (590), Expect = 2e-60
 Identities = 138/487 (28%), Positives = 246/487 (50%), Gaps = 20/487 (4%)

Query: 1   MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60
           ++A  Q   ++  Y   L+ +     +   +  ++ + GR +  ++ ALS  A+  S W 
Sbjct: 12  VDANWQTYIMIAVYFLILMLLAFTYKQATGNLSEYMLGGRSIGPYITALSAGASDMSGWM 71

Query: 61  LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKY-DAVTFVDYIAKRHPE 119
           ++GLPG  ++ GL+A+W  IG  LG  + + V A RLR   E   DA+T  D+   R  +
Sbjct: 72  IMGLPGSVYSTGLSAMWITIGLTLGAYINYFVVAPRLRVYTELAGDAITLPDFFKNRLND 131

Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179
               ++I+    I  FF  Y  + ++ GGK+  + FGLD   G+++ A +++ YT  GG 
Sbjct: 132 KNNVLKIISGLIIVVFFTLYTHSGFVSGGKLFESAFGLDYHFGLILVAFIVIFYTFFGGY 191

Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239
            +V+ TD  Q ++M++ +++ PIV ++ +      +  +     +    K  + +G    
Sbjct: 192 LAVSITDFFQGVIMLIAMVMVPIVAMMNLNGWGTFHDVAAMKPTNLNLFKGLSFIG---- 247

Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299
                 +I+ FSW  GY  G P + +RFM+IK  K    AR +GI W  +  +GA+ +G 
Sbjct: 248 ------IISLFSWGLGYF-GQPHIIVRFMSIKSHKMLPKARRLGISWMAVGLLGAVAVGL 300

Query: 300 IGIAIFGPNGLK--DPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFS 357
            GIA      +K  DPE +   +   LF P +    +   +AA++ST  S L+++S+  +
Sbjct: 301 TGIAFVPAYHIKLEDPETLFIVMSQVLFHPLVGGFLLAAILAAIMSTISSQLLVTSSSLT 360

Query: 358 ENILKPYIYKNEA--DPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGD 415
           E+  K    + +A  D ++ +M+ RL+ + + I+A+ +A+  P+  I  +VG  WAG G 
Sbjct: 361 EDFYKLIRGEEKAKTDQKEFVMIGRLSVLVVAIVAIAIAW-NPNDTILNLVGNAWAGFGA 419

Query: 416 TFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWIS---SGLDAKVSVRLMNFIVTFIVA 472
           +FS +V+  L+WK          +++G L  + WI+             L   I  FIV+
Sbjct: 420 SFSPLVLFALYWKGLTRAGAVSGMVSGALVVIVWIAWIKPLAHINEIFGLYEIIPGFIVS 479

Query: 473 IIATYAI 479
           +I TY +
Sbjct: 480 VIVTYVV 486


>pir||T48676 proline uptake protein [validated] - Staphylococcus aureus
           >gi|2565311|gb|AAC38087.1| (AF024571) high affinity
           proline permease [Staphylococcus aureus]
           Length = 497
           
 Score =  231 bits (582), Expect = 2e-59
 Identities = 137/487 (28%), Positives = 245/487 (50%), Gaps = 20/487 (4%)

Query: 1   MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60
           ++A  Q   ++  Y   L+ +     +   +  ++ + GR +  ++ ALS  A+  S W 
Sbjct: 12  VDANWQTYIMIAVYFLILMLLAFTYKQATGNLSEYMLGGRSIGPYITALSAGASDMSGWM 71

Query: 61  LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKY-DAVTFVDYIAKRHPE 119
           ++GLPG  ++ GL+A+W  IG  LG  + + V A RLR   E   DA+T  D+   R  +
Sbjct: 72  IMGLPGSVYSTGLSAMWITIGLTLGAYINYFVVAPRLRVYTELAGDAITLPDFFKNRLND 131

Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179
               ++I+    I  FF  Y  + ++ GGK+  + FGLD   G+++ A +++ YT  GG 
Sbjct: 132 KNNVLKIISGLIIIVFFTLYTHSGFVSGGKLFESAFGLDYHFGLILVAFIVIFYTFFGGY 191

Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239
            +V+ TD  Q ++M++ +++ PIV ++ +      +  +     +    K  + +G    
Sbjct: 192 LAVSITDFFQGVIMLIAMVMVPIVAMMNLNGWGTFHDVAAMKPTNLNLFKGLSFIG---- 247

Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299
                 +I+ FSW  GY  G P + +RFM+IK  K    AR +GI W  +  +GA+ +G 
Sbjct: 248 ------IISLFSWGLGYF-GQPHIIVRFMSIKSHKMLPKARRLGISWMAVGLLGAVAVGL 300

Query: 300 IGIAIFGPNGLK--DPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFS 357
            GIA      +K  DPE +   +   LF P +    +   +AA++ST  S L+++S+  +
Sbjct: 301 TGIAFVPAYHIKLEDPETLFIVMSQVLFHPLVGGFLLAAILAAIMSTISSQLLVTSSSLT 360

Query: 358 ENILKPYIYKNEA--DPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGD 415
           E+  K    + +A    ++ +M+ RL+ + + I+A+ +A+  P+  I  +VG  WAG G 
Sbjct: 361 EDFYKLIRGEEKAKTHQKEFVMIGRLSVLVVAIVAIAIAW-NPNDTILNLVGNAWAGFGA 419

Query: 416 TFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWIS---SGLDAKVSVRLMNFIVTFIVA 472
           +FS +V+  L+WK          +++G L  + WI+             L   I  FIV+
Sbjct: 420 SFSPLVLFALYWKGLTRAGAVSGMVSGALVVIVWIAWIKPLAHINEIFGLYEIIPGFIVS 479

Query: 473 IIATYAI 479
           +I TY +
Sbjct: 480 VIVTYVV 486


>pir||B81297 sodium/proline symporter Cj1502c [imported] - Campylobacter jejuni
           (strain NCTC 11168) >gi|6968927|emb|CAB73923.1|
           (AL139078) sodium/proline symporter [Campylobacter
           jejuni]
           Length = 495
           
 Score =  229 bits (577), Expect = 7e-59
 Identities = 142/482 (29%), Positives = 250/482 (51%), Gaps = 22/482 (4%)

Query: 1   MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60
           ++  T I  + V Y   ++ +G Y  ++ K+ +D+ + GR +   ++ALS  A+  S W 
Sbjct: 10  VQINTPIAVMFVVYALLMLYIGFYFYKQNKNSEDYFLGGRTMGPVISALSAGASDMSGWL 69

Query: 61  LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKY-DAVTFVDYIAKRHPE 119
           L+GLPG  + +G    + AIG  +G  + W   A RLR       +++T  DY   R  +
Sbjct: 70  LMGLPGALYVSGFIDSYIAIGLTIGASLNWIFVAKRLRIYTSVIANSLTIPDYFETRFDD 129

Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179
            +  +RI+ +  I  FF FYV +  + G K+  + FG+     +    ++I+ YT +GG 
Sbjct: 130 DKHILRIVCAVVILIFFTFYVSSGLVSGAKLFESTFGIRYDYALTTGTIIIVAYTFLGGY 189

Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239
           K+V +TD +Q ++M++ LI+ P+V + ++    E  A ++   +    +        M  
Sbjct: 190 KAVCWTDMIQGLLMMMALIIVPLVMLYHLGGFGE--AMNIVREIKPQAL-------SMGE 240

Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299
              IV +I+  +W  GY  G P + +RFM+I+  K+  +A  IGI W  +  + A MIG 
Sbjct: 241 GVGIVSIISALAWGLGYF-GQPHILVRFMSIRSTKDIPMATFIGIAWMAVCLLSACMIGI 299

Query: 300 IGIAIFG--PNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFS 357
           +GIA        L+DPE++   +   LF P +A + ++  +AA++STA S L++SS+  +
Sbjct: 300 LGIAYVHKFELSLQDPEKIFIVMSQLLFNPWIAGILLSAILAAIMSTASSQLLVSSSTIA 359

Query: 358 ENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTF 417
           E+  K  I++ +A     L + +L  + + +IA +++    S ++ +IV Y WAG G +F
Sbjct: 360 EDFYKK-IFREDAPSHIVLNLGKLGVLLVAVIAFLISTDKNSSVL-SIVSYAWAGFGASF 417

Query: 418 SVIVILTLFWKRFHGKAVPPTIIAGLLFTVFW---ISSGLDAKVSVRLMNFIVTFIVAII 474
             +++ +LFW R         +I G    V W    +SGL   V      F+V  +V II
Sbjct: 418 GSVMLFSLFWSRMTRVGAILGMITGAATVVLWKNFANSGLYEIVP----GFLVASVVIII 473

Query: 475 AT 476
           A+
Sbjct: 474 AS 475


>pir||G81202 sodium/proline symporter NMB0402 [imported] - Neisseria
           meningitidis (group B strain MD58, group A strain Z2491)
           >gi|7225624|gb|AAF40841.1| (AE002396) sodium/proline
           symporter [Neisseria meningitidis MC58]
           >gi|7380708|emb|CAB85299.1| (AL162758) sodium/proline
           symporter [Neisseria meningitidis Z2491]
           Length = 508
           
 Score =  228 bits (576), Expect = 9e-59
 Identities = 143/482 (29%), Positives = 248/482 (50%), Gaps = 28/482 (5%)

Query: 14  YLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGFAFAAGL 73
           YL  ++ +G+      ++  D+ + GR L  +V A+S  A+  S W L+GLPG  + +GL
Sbjct: 11  YLVAVLLIGLAAYFSTRNFDDYILGGRSLGPFVTAMSAGASDMSGWLLMGLPGAIYLSGL 70

Query: 74  AAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPEAEKWIRILGSATI 132
              W AIG ++G    W + AGRLR   E   +A+T  DY   R       ++++ +  I
Sbjct: 71  NEAWIAIGLLVGAYFNWLLVAGRLRVHTEYANNALTLPDYFFHRFGAGGHLMKVVSALII 130

Query: 133 AFFFFFYVGAQYLGGGKVLNTLF-GLDPKLGMLITALVILPYTVMGGLKSVAYTDTVQAI 191
            FFF  Y  +  + G  +  +LF G+     M + A   + YT +GG  +V++TDT+QA 
Sbjct: 131 LFFFTIYCASGIVAGATLFQSLFEGMTYNQAMWLGAGATIAYTFLGGFLAVSWTDTLQAS 190

Query: 192 VMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAAIVFVIAEFS 251
           +MI  LI+ P++  + +    ++ A ++ +  +  G +Y ++  G      ++ +I+  +
Sbjct: 191 LMIFALILTPVMVYLGLGGAEQMSA-AIQSVAAGTGKEYGSLFAG----TTVIGIISTAA 245

Query: 252 WFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGWIGIAIFGPNGLK 311
           W  GY  G P +  RFMA +  K+   AR IG+ W  +   GA+ +G+ GIA FG N  K
Sbjct: 246 WGLGYF-GQPHILARFMAAESAKSLVSARRIGMTWMALCLAGAVAVGYFGIAYFGANPDK 304

Query: 312 ------DPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSENILKPYI 365
                 + E++  ++   LF P +A + ++  +AA++ST    L++ S+  +E+  K ++
Sbjct: 305 VSSMSGNHERIFIALSTLLFNPWIAGIILSAILAAVMSTLSCQLLVCSSAITEDFYKGFL 364

Query: 366 YKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVIVILTL 425
            KN A   + + V RL  +++ +I++++A   P+  +  +V Y WAG G  F  IVIL++
Sbjct: 365 RKN-AQQSELVWVGRLMVLAIAVISILIA-SDPNSKVLGLVSYAWAGFGAAFGPIVILSV 422

Query: 426 FWKRFHGKAVPPTIIAGLLFTVFWI-----------SSGLDAKVSVRLMNFIVTFIVAII 474
            WKR         ++AG L  V W             SGL     + +  FIV  IVA++
Sbjct: 423 LWKRITAYGALSGMVAGALTVVVWAEWVKKPAQAAGESGLLTMYEI-VPGFIVCLIVAVL 481

Query: 475 AT 476
            +
Sbjct: 482 VS 483


>pir||JC2382 sodium/proline symporter - Pseudomonas fluorescens
           >gi|509694|dbj|BAA06838.1| (D32069) proline permease
           [Pseudomonas fluorescens] >gi|913690|gb|AAC60490.1|
           (S76070) proline permease [Pseudomonas fluorescens,
           Peptide, 494 aa] >gi|1092517|prf||2024229A Pro permease
           [Pseudomonas fluorescens]
           Length = 494
           
 Score =  228 bits (575), Expect = 1e-58
 Identities = 144/487 (29%), Positives = 236/487 (47%), Gaps = 26/487 (5%)

Query: 1   MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60
           M      L   V Y+  ++ +G+   R   +  D+ + GR L   V ALS  A+  S W 
Sbjct: 1   MSVSNPTLITFVIYIAAMVLIGLMAYRSTNNLSDYILGGRSLGSVVTALSAGASDMSGWL 60

Query: 61  LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119
           L+GLPG  + +GL+  W AIG ++G  + W   AGRLR + E   DA+T  DY + R  +
Sbjct: 61  LMGLPGAIYMSGLSESWIAIGLIVGAYLNWLFVAGRLRVQTEHNGDALTLPDYFSSRFED 120

Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179
               +RI+ +  I  FF  Y  +  + G ++  + FG+  +  +   A   + YT +GG 
Sbjct: 121 KSGLLRIISAVVILVFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIAYTFIGGF 180

Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELY-ATSVTAALSKAGVKYSTILGGMA 238
            +V++TDTVQA +MI  LI+ PI+ ++        + A       S   +K +T +G   
Sbjct: 181 LAVSWTDTVQATLMIFALILTPIIVLLATGGVDTTFLAIEAKDPTSFDMLKNTTFIG--- 237

Query: 239 GAAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIG 298
                  +I+   W  GY  G P +  RFMA    K+   AR I + W I+   G + +G
Sbjct: 238 -------IISLMGWGLGYF-GQPHILARFMAADSVKSIAKARRISMTWMILCLGGTVAVG 289

Query: 299 WIGIAIFGPNG------LKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILS 352
           + GIA F  +        ++PE+V   +   LF P +A V ++  +AA++ST    L++ 
Sbjct: 290 FFGIAYFSAHPEVAGPVTENPERVFIELAKILFNPWVAGVLLSAILAAVMSTLSCQLLVC 349

Query: 353 STEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAG 412
           S+  +E+  K ++ K  A  R+ + V RL  + + +IA+ MA   P + +  +V Y WAG
Sbjct: 350 SSALTEDFYKAFLRKG-ASQRELVWVGRLMVLVVALIAIAMA-ANPENRVLGLVSYAWAG 407

Query: 413 IGDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSGLDAKVSVRLMNFIVTFIVA 472
            G  F  +V++++ WK          I+ G +  + W    L     + L   I  FI A
Sbjct: 408 FGAAFGPVVLISVIWKHMTRNGALAGILVGAITVIVWKHFEL-----LGLYEIIPGFIFA 462

Query: 473 IIATYAI 479
            +A Y +
Sbjct: 463 SLAIYFV 469


>pir||F83547 sodium/proline symporter PutP PA0783 [imported] - Pseudomonas
           aeruginosa (strain PAO1)
           >gi|9946673|gb|AAG04172.1|AE004513_4 (AE004513)
           sodium/proline symporter PutP [Pseudomonas aeruginosa]
           Length = 506
           
 Score =  227 bits (573), Expect = 2e-58
 Identities = 137/456 (30%), Positives = 226/456 (49%), Gaps = 19/456 (4%)

Query: 1   MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60
           M   T  L   V Y+  ++ +G+   R   +  D+ + GR L  +V ALS  A+  S W 
Sbjct: 1   MSVNTPTLITFVIYIAAMVLIGLAAYRSTNNFSDYILGGRSLGSFVTALSAGASDMSGWL 60

Query: 61  LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119
           L+GLPG  + +GL+  W AIG ++G  + W   AGRLR + E   +A+T  DY   R  +
Sbjct: 61  LMGLPGAVYLSGLSESWIAIGLIVGAYLNWLFVAGRLRVQTEHNGNALTLPDYFTNRFED 120

Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179
             + +RI  +  I  FF  Y  +  + G ++  + FGL  +  +   A   + YT +GG 
Sbjct: 121 NSRLLRIFSALVILVFFTIYCASGIVAGARLFESTFGLSYETALWAGAAATIAYTFIGGF 180

Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239
            +V++TDTVQA +MI  LI+ P++ ++           + TA   K    +  + G    
Sbjct: 181 LAVSWTDTVQASLMIFALILTPVIVMLATGG----VEPTFTAIELKDATSFDMLKG---- 232

Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299
            A+ + VI+  +W  GY  G P +  RFMA    K+   AR I + W I+   GA+ +G+
Sbjct: 233 -ASFIGVISLMAWGLGYF-GQPHILARFMAADSVKSIPAARRISMTWMILCLGGAVAVGF 290

Query: 300 IGIAIFGPNG------LKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353
            GIA F  +        ++PE+V   +   LF P +A V ++  +AA++ST    L++ S
Sbjct: 291 FGIAYFQAHPEQAGAVSENPERVFIELAKILFNPWIAGVLLSAILAAVMSTLSCQLLVCS 350

Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413
           +  +E+  K ++ K  A   + + V R   + + +IA+ +A   P + +  +V Y WAG 
Sbjct: 351 SALTEDFYKAFLRKG-ASQLELVWVGRAMVLLVAVIAIWLA-SNPENRVLGLVSYAWAGF 408

Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFW 449
           G  F  +V+ +L WKR         +I G    + W
Sbjct: 409 GAAFGPLVLFSLLWKRMTRNGALAGMIVGAATVILW 444


>pir||A71980 sodium/proline symporter - Helicobacter pylori (strain J99)
           >gi|4154554|gb|AAD05631.1| (AE001444) sodium/proline
           symporter [Helicobacter pylori J99]
           Length = 496
           
 Score =  226 bits (571), Expect = 4e-58
 Identities = 138/478 (28%), Positives = 247/478 (50%), Gaps = 20/478 (4%)

Query: 5   TQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGL 64
           T I+ + V Y   ++ +G Y  ++ ++ +D+ +  R +   ++ALS  A+  S W L+GL
Sbjct: 8   TPIVTMFVVYSLLMLYIGFYFYKQNETTEDYFLGDRSMGPVISALSAGASDMSGWLLMGL 67

Query: 65  PGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKY-DAVTFVDYIAKRHPEAEKW 123
           PG  +  GL     AIG  LG ++ W   A RLR       +++T  DY   R  + +  
Sbjct: 68  PGALYVGGLINSHIAIGLSLGALINWVFVAKRLRIYTSVIANSITISDYFETRFSDDKHI 127

Query: 124 IRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVA 183
           +R++ +  I  FF FY+ +  + G K+    FG+     + I  L+I+ YT +GG K+V 
Sbjct: 128 LRLISAFVILIFFIFYISSGLVSGAKLFEATFGIQYTYALSIGTLIIVSYTFLGGYKAVC 187

Query: 184 YTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAAI 243
           +TD +Q ++M+  LIV PIV +I++    E     +   +    + +          +++
Sbjct: 188 WTDLIQGLLMMSALIVVPIVMIIHLGGIGE--GIKIIREIKPENLSF-------LQGSSV 238

Query: 244 VFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGWIGIA 303
           V +I+  +W  GY  G P + +RFM+I+  ++   A  IGI W +I+ IGA ++G +G+A
Sbjct: 239 VAIISSLAWGLGYF-GQPHILVRFMSIRSIRDVPKATTIGISWMVISLIGACVMGLLGVA 297

Query: 304 IFG--PNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSENIL 361
                   L+DPE++   +   LF P +  + ++  +AA++STA S L++SS+  +E+  
Sbjct: 298 YVHKFDLSLEDPEKIFIVMSQLLFNPWITGILLSAILAAVMSTASSQLLVSSSTIAEDFY 357

Query: 362 KPYIYKNEADPRKSLM-VSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVI 420
                KN   P+K +M +SRL+ + +  IA  ++    +  I +IV Y WAG G +F  +
Sbjct: 358 ATIFNKNA--PQKLVMTISRLSVLGVACIAFFIS-TDKNASILSIVSYAWAGFGASFGSV 414

Query: 421 VILTLFWKRFHGKAVPPTIIAGLLFTVFWISSGLDAKVSVRLMNFIVTFIVAIIATYA 478
           ++ +LFW R         +++G    + +   G   K  + +   +  FIVA +A  A
Sbjct: 415 ILFSLFWSRMTRIGAIAGMLSGASTVILYDKFG---KSFLDIYEIVPGFIVASVAIVA 469


>pir||G64526 sodium/proline symporter - Helicobacter pylori (strain 26695)
           >gi|2313133|gb|AAD07125.1| (AE000527) proline permease
           (putP) [Helicobacter pylori 26695]
           Length = 496
           
 Score =  224 bits (566), Expect = 1e-57
 Identities = 133/474 (28%), Positives = 245/474 (51%), Gaps = 18/474 (3%)

Query: 5   TQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGL 64
           T I+ + + Y   ++ +G Y  ++ ++ +D+ +  R +   ++ALS  A+  S W L+GL
Sbjct: 8   TPIVTMFIVYSLLMLYIGFYFYKQNETTEDYFLGDRSMGPVISALSAGASDMSGWLLMGL 67

Query: 65  PGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKY-DAVTFVDYIAKRHPEAEKW 123
           PG  +  GL     AIG  LG ++ W   A RLR       +++T  DY   R  + +  
Sbjct: 68  PGALYVGGLINSHIAIGLSLGALINWVFVAKRLRIYTSVIANSITISDYFETRFSDDKHI 127

Query: 124 IRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVA 183
           +R++ +  I  FF FY+ +  + G K+    FG+     + I  L+I+ YT +GG K+V 
Sbjct: 128 LRLISAFVILIFFIFYISSGLVSGAKLFEATFGIQYTYALSIGTLIIVSYTFLGGYKAVC 187

Query: 184 YTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAAI 243
           +TD +Q ++M+  LIV PIV +I++    E     +   +    + +          +++
Sbjct: 188 WTDLIQGLLMMSALIVVPIVMIIHLGGIGE--GIKIIREIKPENLSF-------LQGSSV 238

Query: 244 VFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGWIGIA 303
           V +I+  +W  GY  G P + +RFM+I+  ++   A  IGI W +I+ IGA ++G +G+A
Sbjct: 239 VAIISSLAWGLGYF-GQPHILVRFMSIRSIRDVPKATTIGISWMVISLIGACVMGLLGVA 297

Query: 304 IFG--PNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSENIL 361
                   L+DPE++   +   LF P +  + ++  +AA++STA S L++SS+  +E+  
Sbjct: 298 YVHKFDLSLEDPEKIFIVMSQLLFNPWITGILLSAILAAVMSTASSQLLVSSSTIAEDFY 357

Query: 362 KPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVIV 421
              I+  +A  +  + +SRL+ + +  IA  ++    +  I +IV Y WAG G +F  ++
Sbjct: 358 AT-IFNKDAPQKLVMAISRLSVLGVACIAFFIS-TDRNASILSIVSYAWAGFGASFGSVI 415

Query: 422 ILTLFWKRFHGKAVPPTIIAGLLFTVFWISSGLDAKVSVRLMNFIVTFIVAIIA 475
           + +LFW R         +++G    + +   G   K  + +   +  FIVA +A
Sbjct: 416 LFSLFWSRMTRIGAIAGMLSGASTVILYDKFG---KSFLDIYEIVPGFIVASVA 466


>pir||S10220 sodium/proline symporter - Salmonella typhimurium
           Length = 502
           
 Score =  224 bits (565), Expect = 2e-57
 Identities = 134/460 (29%), Positives = 230/460 (49%), Gaps = 19/460 (4%)

Query: 1   MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60
           M   T +L     Y+  +I +G    R  K+  D+ + GR L  +V ALS  A+  S W 
Sbjct: 1   MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60

Query: 61  LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119
           L+GLPG  F +G++  W AIG  LG  + W + AGRLR   E   +A+T  DY   R  +
Sbjct: 61  LMGLPGAIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFED 120

Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179
             + +RI+ +  I  FF  Y G+  + G ++  + FG+  +  +   A   + YT +GG 
Sbjct: 121 KSRVLRIISALVILLFFTIYCGSGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGF 180

Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239
            +V++TDTVQA +MI  LI+ P++ ++ +    E         + +  ++   +L G+  
Sbjct: 181 LAVSWTDTVQASLMIFALILTPVMVIVGVGGFSE-----SLEVIKQKSIENVDMLKGL-- 233

Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299
               V +I+   W  GY  G P +  RFMA     +   AR I + W I+   GA+ +G+
Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGF 290

Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353
            GIA F  N        ++ E+V   +   LF P +A V ++  +AA++ST    +++ S
Sbjct: 291 FGIAYFNNNPALAGAVNQNSERVFIELAQILFNPWIAGVLLSAILAAVMSTLSCQMLVCS 350

Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413
           +  +E++ K ++ K+ A  ++ + V R+  + + +IA+ +A   P + +  +V Y WAG 
Sbjct: 351 SAITEDLYKAFLRKS-ASQQELVWVGRVMVLVVALIAIALA-ANPDNRVLGLVSYAWAGF 408

Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453
           G  F  +V+ ++ W R         +I G +  + W   G
Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGAVTVIVWKQYG 448


>gb|AAA24461.1| (L01132) proline permease [Escherichia coli]
           >gi|147447|gb|AAA24467.1| (L01154) proline permease
           [Escherichia coli] >gi|147451|gb|AAA24469.1| (L01156)
           proline permease [Escherichia coli]
           Length = 489
           
 Score =  223 bits (562), Expect = 4e-57
 Identities = 134/460 (29%), Positives = 231/460 (50%), Gaps = 19/460 (4%)

Query: 1   MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60
           M   T +L     Y+  +I +G    R  K+  D+ + GR L  +V ALS  A+  S W 
Sbjct: 1   MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60

Query: 61  LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119
           L+GLPG  F +G++  W AIG  LG  + W + AGRLR   E   +A+T  DY   R  +
Sbjct: 61  LMGLPGAVFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEYNNNALTLPDYFTGRFED 120

Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179
             + +RI+ +  I  FF  Y  +  + G ++  + FG+  +  +   A   + YT +GG 
Sbjct: 121 KSRILRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATILYTFIGGF 180

Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239
            +V++TDTVQA +MI  LI+ P++ +I +      +  S+     K+ ++   +L G+  
Sbjct: 181 LAVSWTDTVQASLMIFALILTPVIVIISVGG----FGDSLEVIKQKS-IENVDMLKGL-- 233

Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299
               V +I+   W  GY  G P +  RFMA     +   AR I + W I+   GA+ +G+
Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGF 290

Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353
            GIA F  +        ++ E+V   +   LF P +A + ++  +AA++ST    L++ S
Sbjct: 291 FGIAYFNEHPAVAGAVNQNAERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCS 350

Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413
           +  +E++ K ++ K +A  ++ + V R+  + + ++A+ +A   P + +  +V Y WAG 
Sbjct: 351 SAITEDLYKAFLRK-QASQKELVWVGRVMVLVVALVAIALA-ANPENRVLGLVSYAWAGF 408

Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453
           G  F  +V+ ++ W R         +I G L  + W   G
Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGALTVIVWKQFG 448


>sp|P07117|PUTP_ECOLI SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE) >gi|72512|pir||JGECPP
           sodium/proline symporter - Escherichia coli
           >gi|42602|emb|CAA29143.1| (X05653) putP proline carrier
           (AA 1-502) [Escherichia coli]
           >gi|1651504|dbj|BAA35793.1| (D90738) Proline carrier
           protein [Escherichia coli] >gi|1787251|gb|AAC74100.1|
           (AE000203) major sodium/proline symporter [Escherichia
           coli K12] >gi|225963|prf||1404369A Pro carrier protein
           [Escherichia coli]
           Length = 502
           
 Score =  222 bits (561), Expect = 5e-57
 Identities = 134/460 (29%), Positives = 231/460 (50%), Gaps = 19/460 (4%)

Query: 1   MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60
           M   T +L     Y+  +I +G    R  K+  D+ + GR L  +V ALS  A+  S W 
Sbjct: 1   MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60

Query: 61  LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119
           L+GLPG  F +G++  W AIG  LG  + W + AGRLR   E   +A+T  DY   R  +
Sbjct: 61  LMGLPGAVFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEYNNNALTLPDYFTGRFED 120

Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179
             + +RI+ +  I  FF  Y  +  + G ++  + FG+  +  +   A   + YT +GG 
Sbjct: 121 KSRILRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATILYTFIGGF 180

Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239
            +V++TDTVQA +MI  LI+ P++ +I +      +  S+     K+ ++   +L G+  
Sbjct: 181 LAVSWTDTVQASLMIFALILTPVIVIISVGG----FGDSLEVIKQKS-IENVDMLKGL-- 233

Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299
               V +I+   W  GY  G P +  RFMA     +   AR I + W I+   GA+ +G+
Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGF 290

Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353
            GIA F  +        ++ E+V   +   LF P +A + ++  +AA++ST    L++ S
Sbjct: 291 FGIAYFNDHPALAGAVNQNAERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCS 350

Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413
           +  +E++ K ++ K+ A  ++ + V R+  + + ++A+ +A   P + +  +V Y WAG 
Sbjct: 351 SAITEDLYKAFLRKH-ASQKELVWVGRVMVLVVALVAIALA-ANPENRVLGLVSYAWAGF 408

Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453
           G  F  +V+ ++ W R         +I G L  + W   G
Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGALTVIVWKQFG 448


>sp|P10502|PUTP_SALTY SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE)
           >gi|47849|emb|CAA36802.1| (X52573) proline permease (AA
           1-502) [Salmonella typhimurium]
           Length = 502
           
 Score =  222 bits (561), Expect = 5e-57
 Identities = 134/460 (29%), Positives = 229/460 (49%), Gaps = 19/460 (4%)

Query: 1   MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60
           M   T +L     Y+  +I +G    R  K+  D+ + GR L  +V ALS  A+  S W 
Sbjct: 1   MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60

Query: 61  LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119
           L+GLPG  F +G++  W AIG  LG  + W + AGRLR   E   +A+T  DY   R  +
Sbjct: 61  LMGLPGAIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFED 120

Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179
             + +RI+ +  I  FF  Y  +  + G ++  + FG+  +  +   A   + YT +GG 
Sbjct: 121 KSRVLRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGF 180

Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239
            +V++TDTVQA +MI  LI+ P++ ++ +    E         + +  ++   +L G+  
Sbjct: 181 LAVSWTDTVQASLMIFALILTPVMVIVGVGGFSE-----SLEVIKQKSIENVDMLKGL-- 233

Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299
               V +I+   W  GY  G P +  RFMA     +   AR I + W I+   GA+ +G+
Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGF 290

Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353
            GIA F  N        ++ E+V   +   LF P +A V ++  +AA++ST    L++ S
Sbjct: 291 FGIAYFNNNPALAGAVNQNSERVFIELAQILFNPWIAGVLLSAILAAVMSTLSCQLLVCS 350

Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413
           +  +E++ K ++ K+ A  ++ + V R+  + + +IA+ +A   P + +  +V Y WAG 
Sbjct: 351 SAITEDLYKAFLRKS-ASQQELVWVGRVMVLVVALIAIALA-ANPDNRVLGLVSYAWAGF 408

Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453
           G  F  +V+ ++ W R         +I G +  + W   G
Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGAVTVIVWKQYG 448


>gb|AAA99288.1| (L01146) proline permease [Salmonella sp.]
           >gi|154314|gb|AAA99289.1| (L01147) proline permease
           [Salmonella sp.]
           Length = 489
           
 Score =  222 bits (561), Expect = 5e-57
 Identities = 133/460 (28%), Positives = 230/460 (49%), Gaps = 19/460 (4%)

Query: 1   MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60
           M   T +L     Y+  +I +G    R  K+  D+ + GR L  +V ALS  A+  S W 
Sbjct: 1   MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60

Query: 61  LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119
           L+GLPG  F +G++  W AIG  LG  + W + AGRLR   E   +A+T  DY   R  +
Sbjct: 61  LMGLPGAIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFED 120

Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179
             + +RI+ +  I  FF  Y  +  + G ++  + FG+  +  +   A   + YT +GG 
Sbjct: 121 KSRVLRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGF 180

Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239
            +V++TDTVQA +MI  LI+ P++ ++ +    E         + +  ++   +L G+  
Sbjct: 181 LAVSWTDTVQASLMIFALILTPVMVIVGVGGFSE-----SLEVIKQKSIENVDMLKGL-- 233

Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299
               V +I+   W  GY  G P +  RFMA     +   AR I + W I+   GA+ +G+
Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGF 290

Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353
            GIA F  N        ++ E+V   +   LF P +A + ++  +AA++ST    L++ S
Sbjct: 291 FGIAYFNNNPALAGAVNQNSERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCS 350

Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413
           +  +E++ K ++ K+ A  ++ + V R+  + + +IA+ +A   P++ +  +V Y WAG 
Sbjct: 351 SAITEDLYKAFLRKS-ASQQELVWVGRVMVLVVALIAIALA-ANPNNRVLGLVSYAWAGF 408

Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453
           G  F  +V+ ++ W R         +I G +  + W   G
Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGAVTVIVWKQYG 448


>gb|AAA24463.1| (L01150) proline permease [Escherichia coli]
           >gi|147441|gb|AAA24464.1| (L01151) proline permease
           [Escherichia coli]
           Length = 489
           
 Score =  222 bits (561), Expect = 5e-57
 Identities = 134/460 (29%), Positives = 231/460 (50%), Gaps = 19/460 (4%)

Query: 1   MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60
           M   T +L     Y+  +I +G    R  K+  D+ + GR L  +V ALS  A+  S W 
Sbjct: 1   MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60

Query: 61  LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119
           L+GLPG  F +G++  W AIG  LG  + W + AGRLR   E   +A+T  DY   R  +
Sbjct: 61  LMGLPGAVFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEYNNNALTLPDYFTGRFED 120

Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179
             + +RI+ +  I  FF  Y  +  + G ++  + FG+  +  +   A   + YT +GG 
Sbjct: 121 KSRILRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATILYTFIGGF 180

Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239
            +V++TDTVQA +MI  LI+ P++ +I +      +  S+     K+ ++   +L G+  
Sbjct: 181 LAVSWTDTVQASLMIFALILTPVIVIISVGG----FGDSLEVIKQKS-IENVDMLKGL-- 233

Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299
               V +I+   W  GY  G P +  RFMA     +   AR I + W I+   GA+ +G+
Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGF 290

Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353
            GIA F  +        ++ E+V   +   LF P +A + ++  +AA++ST    L++ S
Sbjct: 291 FGIAYFNDHPALAGAVNQNAERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCS 350

Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413
           +  +E++ K ++ K+ A  ++ + V R+  + + ++A+ +A   P + +  +V Y WAG 
Sbjct: 351 SAITEDLYKAFLRKH-ASQKELVWVGRVMVLVVALVAIALA-ANPENRVLGLVSYAWAGF 408

Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453
           G  F  +V+ ++ W R         +I G L  + W   G
Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGALTVIVWKQFG 448


>gb|AAA27199.1| (L01135) proline permease [Salmonella typhimurium]
           Length = 489
           
 Score =  222 bits (561), Expect = 5e-57
 Identities = 134/460 (29%), Positives = 229/460 (49%), Gaps = 19/460 (4%)

Query: 1   MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60
           M   T +L     Y+  +I +G    R  K+  D+ + GR L  +V ALS  A+  S W 
Sbjct: 1   MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60

Query: 61  LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119
           L+GLPG  F +G++  W AIG  LG  + W + AGRLR   E   +A+T  DY   R  +
Sbjct: 61  LMGLPGAIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFED 120

Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179
             + +RI+ +  I  FF  Y  +  + G ++  + FG+  +  +   A   + YT +GG 
Sbjct: 121 KSRVLRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGF 180

Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239
            +V++TDTVQA +MI  LI+ P++ ++ +    E         + +  ++   +L G+  
Sbjct: 181 LAVSWTDTVQASLMIFALILTPVMVIVGVGGFSE-----SLEVIKQKSIENVDMLKGL-- 233

Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299
               V +I+   W  GY  G P +  RFMA     +   AR I + W I+   GA+ +G+
Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGF 290

Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353
            GIA F  N        ++ E+V   +   LF P +A V ++  +AA++ST    L++ S
Sbjct: 291 FGIAYFNNNPALAGAVNQNSERVFIELAQILFNPWIAGVLLSAILAAVMSTLSCQLLVCS 350

Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413
           +  +E++ K ++ K+ A  ++ + V R+  + + +IA+ +A   P + +  +V Y WAG 
Sbjct: 351 SAITEDLYKAFLRKS-ASQQELVWVGRVMVLVVALIAIALA-ANPDNRVLGLVSYAWAGF 408

Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453
           G  F  +V+ ++ W R         +I G +  + W   G
Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGAVTVIVWKQYG 448


>gb|AAA26389.1| (L01134) proline permease [Rickettsia typhi]
           Length = 489
           
 Score =  222 bits (561), Expect = 5e-57
 Identities = 134/460 (29%), Positives = 229/460 (49%), Gaps = 19/460 (4%)

Query: 1   MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60
           M   T +L     Y+  +I +G    R  K+  D+ + GR L  +V ALS  A+  S W 
Sbjct: 1   MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60

Query: 61  LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119
           L+GLPG  F +G++  W AIG  LG  + W + AGRLR   E   +A+T  DY   R  +
Sbjct: 61  LMGLPGAIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFED 120

Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179
             + +RI+ +  I  FF  Y  +  + G ++  + FG+  +  +   A   + YT +GG 
Sbjct: 121 KSRVLRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGF 180

Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239
            +V++TDTVQA +MI  LI+ P++ ++ +    E         + +  ++   +L G+  
Sbjct: 181 LAVSWTDTVQASLMIFALILTPVMVIVGVGGFSE-----SLEVIKQKSIENVDMLKGL-- 233

Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299
               V +I+   W  GY  G P +  RFMA     +   AR I + W I+   GA+ +G+
Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGF 290

Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353
            GIA F  N        ++ E+V   +   LF P +A V ++  +AA++ST    L++ S
Sbjct: 291 FGIAYFNNNPALAGAVNQNSERVFIELAQILFNPWIAGVLLSAILAAVMSTLSCQLLVCS 350

Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413
           +  +E++ K ++ K+ A  ++ + V R+  + + +IA+ +A   P + +  +V Y WAG 
Sbjct: 351 SAITEDLYKAFLRKS-ASQQELVWVGRVMVLVVALIAIALA-ANPDNRVLGLVSYAWAGF 408

Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453
           G  F  +V+ ++ W R         +I G +  + W   G
Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGAVTVIVWKQYG 448


>gb|AAA99282.1| (L01140) proline permease [Salmonella sp.]
           >gi|154302|gb|AAA99283.1| (L01141) proline permease
           [Salmonella sp.]
           Length = 489
           
 Score =  222 bits (561), Expect = 5e-57
 Identities = 133/460 (28%), Positives = 229/460 (48%), Gaps = 19/460 (4%)

Query: 1   MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60
           M   T +L     Y+  ++ +G    R  K+  D+ + GR L  +V ALS  A+  S W 
Sbjct: 1   MAISTPMLVTFCVYIFGMLLIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60

Query: 61  LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119
           L+GLPG  F +G++  W AIG  LG  + W + AGRLR   E   +A+T  DY   R  +
Sbjct: 61  LMGLPGAIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTSRFED 120

Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179
             + +RI+ +  I  FF  Y  +  + G ++  + FG+  +  +   A   + YT +GG 
Sbjct: 121 KSRVLRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGF 180

Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239
            +V++TDTVQA +MI  LI+ P++ ++ +    E         + +  ++   +L G+  
Sbjct: 181 LAVSWTDTVQASLMIFALILTPVMVIVGVGGFSE-----SLEVIKQKSIENVDMLKGL-- 233

Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299
               V +I+   W  GY  G P +  RFMA     +   AR I + W I+   GA+ +G+
Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHHSIVHARRISMTWMILCLTGAVAVGF 290

Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353
            GIA F  N        ++ E+V   +   LF P +A V ++  +AA++ST    L++ S
Sbjct: 291 FGIAFFNNNPALAGAVNQNSERVFIELAQILFNPWIAGVLLSAILAAVMSTLSCQLLVCS 350

Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413
           +  +E++ K ++ K+ A  ++ + V R+  + + +IA+ +A   P + +  +V Y WAG 
Sbjct: 351 SAITEDLYKAFLRKS-AGQQELVWVGRVMVLVVALIAIALA-ANPDNRVLGLVSYAWAGF 408

Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453
           G  F  +V+ ++ W R         +I G +  + W   G
Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGAVTVIVWKQYG 448


>gb|AAA24466.1| (L01153) proline permease [Escherichia coli]
           >gi|147453|gb|AAA24470.1| (L01157) proline permease
           [Escherichia coli] >gi|147455|gb|AAA24471.1| (L01158)
           proline permease [Escherichia coli]
           >gi|147457|gb|AAA24472.1| (L01159) proline permease
           [Escherichia coli]
           Length = 489
           
 Score =  222 bits (561), Expect = 5e-57
 Identities = 134/460 (29%), Positives = 231/460 (50%), Gaps = 19/460 (4%)

Query: 1   MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60
           M   T +L     Y+  +I +G    R  K+  D+ + GR L  +V ALS  A+  S W 
Sbjct: 1   MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60

Query: 61  LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119
           L+GLPG  F +G++  W AIG  LG  + W + AGRLR   E   +A+T  DY   R  +
Sbjct: 61  LMGLPGAVFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEYNNNALTLPDYFTGRFED 120

Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179
             + +RI+ +  I  FF  Y  +  + G ++  + FG+  +  +   A   + YT +GG 
Sbjct: 121 KSRILRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATILYTFIGGF 180

Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239
            +V++TDTVQA +MI  LI+ P++ +I +      +  S+     K+ ++   +L G+  
Sbjct: 181 LAVSWTDTVQASLMIFALILTPVIVIISVGG----FGDSLEVIKQKS-IENVDMLKGL-- 233

Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299
               V +I+   W  GY  G P +  RFMA     +   AR I + W I+   GA+ +G+
Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGF 290

Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353
            GIA F  +        ++ E+V   +   LF P +A + ++  +AA++ST    L++ S
Sbjct: 291 FGIAYFNEHPAVAGAVNQNAERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCS 350

Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413
           +  +E++ K ++ K+ A  ++ + V R+  + + ++A+ +A   P + +  +V Y WAG 
Sbjct: 351 SAITEDLYKAFLRKH-ASQKELVWVGRVMVLVVALVAIALA-ANPENRVLGLVSYAWAGF 408

Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453
           G  F  +V+ ++ W R         +I G L  + W   G
Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGALTVIVWKQFG 448


>gb|AAA24462.1| (L01133) proline permease [Escherichia coli]
           Length = 489
           
 Score =  222 bits (560), Expect = 7e-57
 Identities = 134/460 (29%), Positives = 231/460 (50%), Gaps = 19/460 (4%)

Query: 1   MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60
           M   T +L     Y+  +I +G    R  K+  D+ + GR L  +V ALS  A+  S W 
Sbjct: 1   MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60

Query: 61  LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119
           L+GLPG  F +G++  W AIG  LG  + W + AGRLR   E   +A+T  DY   R  +
Sbjct: 61  LMGLPGAVFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEYNNNALTLPDYFTGRFED 120

Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179
             + +RI+ +  I  FF  Y  +  + G ++  + FG+  +  +   A   + YT +GG 
Sbjct: 121 KSRILRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATILYTFIGGF 180

Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239
            +V++TDTVQA +MI  LI+ P++ +I +      +  S+     K+ ++   +L G+  
Sbjct: 181 LAVSWTDTVQASLMIFALILTPVIVIISVGG----FGDSLEVIKQKS-IENVDMLKGL-- 233

Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299
               V +I+   W  GY  G P +  RFMA     +   AR I + W I+   GA+ +G+
Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGF 290

Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353
            GIA F  +        ++ E+V   +   LF P +A + ++  +AA++ST    L++ S
Sbjct: 291 FGIAYFNEHPSVAGAVNQNAERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCS 350

Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413
           +  +E++ K ++ K+ A  ++ + V R+  + + ++A+ +A   P + +  +V Y WAG 
Sbjct: 351 SAITEDLYKAFLRKH-ASQKELVWVGRVMVLVVALVAIALA-ANPENRVLGLVSYAWAGF 408

Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453
           G  F  +V+ ++ W R         +I G L  + W   G
Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGALTVIVWKQFG 448


>gb|AAA24468.1| (L01155) proline permease [Escherichia coli]
           Length = 489
           
 Score =  222 bits (560), Expect = 7e-57
 Identities = 134/460 (29%), Positives = 231/460 (50%), Gaps = 19/460 (4%)

Query: 1   MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60
           M   T +L     Y+  +I +G    R  K+  D+ + GR L  +V ALS  A+  S W 
Sbjct: 1   MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60

Query: 61  LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119
           L+GLPG  F +G++  W AIG  LG  + W + AGRLR   E   +A+T  DY   R  +
Sbjct: 61  LMGLPGAVFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEYNNNALTLPDYFTGRFED 120

Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179
             + +RI+ +  I  FF  Y  +  + G ++  + FG+  +  +   A   + YT +GG 
Sbjct: 121 KSRILRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATILYTFIGGF 180

Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239
            +V++TDTVQA +MI  LI+ P++ +I +      +  S+     K+ ++   +L G+  
Sbjct: 181 LAVSWTDTVQASLMIFALILTPVIVIISVGG----FGDSLEVIKQKS-IENVDMLKGL-- 233

Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299
               V +I+   W  GY  G P +  RFMA     +   AR I + W I+   GA+ +G+
Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGF 290

Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353
            GIA F  +        ++ E+V   +   LF P +A + ++  +AA++ST    L++ S
Sbjct: 291 FGIAYFNEHPAVAGAVNQNAERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCS 350

Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413
           +  +E++ K ++ K+ A  ++ + V R+  + + ++A+ +A   P + +  +V Y WAG 
Sbjct: 351 SAITEDLYKAFMRKH-ASQKELVWVGRVMVLVVALVAIALA-ANPENRVLGLVSYAWAGF 408

Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453
           G  F  +V+ ++ W R         +I G L  + W   G
Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGALTVIVWKQFG 448


>gb|AAA99290.1| (L01148) proline permease [Salmonella sp.]
           Length = 489
           
 Score =  222 bits (559), Expect = 9e-57
 Identities = 134/460 (29%), Positives = 229/460 (49%), Gaps = 19/460 (4%)

Query: 1   MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60
           M   T +L     Y+  +I +G    R  K+  D+ + GR L  +V ALS  A+  S W 
Sbjct: 1   MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60

Query: 61  LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119
           L+GLPG  F +G++  W AIG  LG  + W + AGRLR   E   +A+T  DY   R  +
Sbjct: 61  LMGLPGAIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFED 120

Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179
             + +RI+ +  I  FF  Y  +  + G ++  + FG+  +  +   A   + YT +GG 
Sbjct: 121 KSRVLRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGF 180

Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239
            +V++TDTVQA +MI  LI+ P++ ++ +    E         + +  ++   +L G+  
Sbjct: 181 LAVSWTDTVQASLMIFALILTPVMVIVGVGGFSE-----SLEVIKQKSIENVDMLKGL-- 233

Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299
               V +I+   W  GY  G P +  RFMA     +   AR I + W I+   GA+ +G+
Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGF 290

Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353
            GIA F  N        ++ E+V   +   LF P +A V ++  +AA++ST    L++ S
Sbjct: 291 FGIAYFNNNPALAGAVNQNSERVFIELAQILFNPWIAGVLLSAILAAVMSTLSCQLLVCS 350

Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413
           +  +E++ K ++ K+ A  ++ + V R+  + + +IA+ +A   P + +  +V Y WAG 
Sbjct: 351 SAITEDLYKAFLRKS-ASQQELVWVGRVMVLVVALIAIALA-ANPDNRVLGLVTYAWAGF 408

Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453
           G  F  +V+ ++ W R         +I G +  + W   G
Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGAVTVIVWKQYG 448


>gb|AAA99291.1| (L01149) proline permease [Salmonella sp.]
           Length = 489
           
 Score =  222 bits (559), Expect = 9e-57
 Identities = 134/460 (29%), Positives = 229/460 (49%), Gaps = 19/460 (4%)

Query: 1   MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60
           M   T +L     Y+  +I +G    R  K+  D+ + GR L  +V ALS  A+  S W 
Sbjct: 1   MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60

Query: 61  LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119
           L+GLPG  F +G++  W AIG  LG  + W + AGRLR   E   +A+T  DY   R  +
Sbjct: 61  LMGLPGAIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFED 120

Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179
             + +RI+ +  I  FF  Y  +  + G ++  + FG+  +  +   A   + YT +GG 
Sbjct: 121 KSRVLRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGF 180

Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239
            +V++TDTVQA +MI  LI+ P++ ++ +    E         + +  ++   +L G+  
Sbjct: 181 LAVSWTDTVQASLMIFALILTPVMVIVGVGGFSE-----SLEVIKQKSIENVDMLKGL-- 233

Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299
               V +I+   W  GY  G P +  RFMA     +   AR I + W I+   GA+ +G+
Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGF 290

Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353
            GIA F  N        ++ E+V   +   LF P +A V ++  +AA++ST    L++ S
Sbjct: 291 FGIAYFNNNPALAGAVNQNSERVFIELAQILFNPWIAGVLLSAILAAVMSTLSCQLLVCS 350

Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413
           +  +E++ K ++ K+ A  ++ + V R+  + + +IA+ +A   P + +  +V Y WAG 
Sbjct: 351 SAITEDLYKAFLRKS-ASQQELVWVGRVMVLVVALIAIALA-ANPDNRVLGLVTYAWAGF 408

Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453
           G  F  +V+ ++ W R         +I G +  + W   G
Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGAVTVIVWKQYG 448


>gb|AAA99278.1| (L01136) proline permease [Salmonella sp.]
           Length = 489
           
 Score =  221 bits (558), Expect = 1e-56
 Identities = 133/460 (28%), Positives = 229/460 (48%), Gaps = 19/460 (4%)

Query: 1   MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60
           M   T +L     Y+  ++ +G    R  K+  D+ + GR L  +V ALS  A+  S W 
Sbjct: 1   MAISTPMLVTFCVYIFGMLLIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60

Query: 61  LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119
           L+GLPG  F +G++  W AIG  LG  + W + AGRLR   E   +A+T  DY   R  +
Sbjct: 61  LMGLPGAIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFED 120

Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179
             + +RI+ +  I  FF  Y  +  + G ++  + FG+  +  +   A   + YT +GG 
Sbjct: 121 KSRVLRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGF 180

Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239
            +V++TDTVQA +MI  LI+ P++ ++ +    E         + +  ++   +L G+  
Sbjct: 181 LAVSWTDTVQASLMIFALILTPVMVIVGVGGFSE-----SLEVIKQKSIENVDMLKGL-- 233

Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299
               V +I+   W  GY  G P +  RFMA     +   AR I + W I+   GA+ +G+
Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGF 290

Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353
            GIA F  N        ++ E+V   +   LF P +A V ++  +AA++ST    L++ S
Sbjct: 291 FGIAYFNNNPALAGAVNQNSERVFIELAQILFNPWVAGVLLSAILAAVMSTLSCQLLVCS 350

Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413
           +  +E++ K ++ K+ A  ++ + V R+  + + +IA+ +A   P + +  +V Y WAG 
Sbjct: 351 SAITEDLYKAFLRKS-ASQQELVWVGRVMVLVVALIAIALA-ANPDNRVLGLVSYAWAGF 408

Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453
           G  F  +V+ ++ W R         +I G +  + W   G
Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGAVTVIVWKQYG 448


>gb|AAA99279.1| (L01137) proline permease [Salmonella sp.]
           Length = 489
           
 Score =  221 bits (558), Expect = 1e-56
 Identities = 133/460 (28%), Positives = 229/460 (48%), Gaps = 19/460 (4%)

Query: 1   MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60
           M   T +L     Y+  ++ +G    R  K+  D+ + GR L  +V ALS  A+  S W 
Sbjct: 1   MAISTPMLVTFCVYIFGMLLIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60

Query: 61  LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119
           L+GLPG  F +G++  W AIG  LG  + W + AGRLR   E   +A+T  DY   R  +
Sbjct: 61  LMGLPGAIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFED 120

Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179
             + +RI+ +  I  FF  Y  +  + G ++  + FG+  +  +   A   + YT +GG 
Sbjct: 121 KSRVLRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGF 180

Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239
            +V++TDTVQA +MI  LI+ P++ ++ +    E         + +  ++   +L G+  
Sbjct: 181 LAVSWTDTVQASLMIFALILTPVMVIVGVGGFSE-----SLEVIKQKSIENVDMLKGL-- 233

Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299
               V +I+   W  GY  G P +  RFMA     +   AR I + W I+   GA+ +G+
Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGF 290

Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353
            GIA F  N        ++ E+V   +   LF P +A V ++  +AA++ST    L++ S
Sbjct: 291 FGIAYFNNNPALAGAVNQNSERVFIELAQILFNPWVAGVLLSAILAAVMSTLSCQLLVCS 350

Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413
           +  +E++ K ++ K+ A  ++ + V R+  + + +IA+ +A   P + +  +V Y WAG 
Sbjct: 351 SAITEDLYKAFLRKS-ASQQELVWVGRVMVLVVALIAIALA-ANPDNRVLGLVSYAWAGF 408

Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453
           G  F  +V+ ++ W R         +I G +  + W   G
Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGAVTVIVWKQYG 448


>gb|AAA24465.1| (L01152) proline permease [Escherichia coli]
           Length = 489
           
 Score =  221 bits (557), Expect = 2e-56
 Identities = 133/460 (28%), Positives = 230/460 (49%), Gaps = 19/460 (4%)

Query: 1   MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60
           M   T +L     Y+  +I +G    R  K+  D+ + GR L  +V ALS  A+  S W 
Sbjct: 1   MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60

Query: 61  LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119
           L+GLPG  F +G++  W AIG  LG  + W + AGRLR   E   +A+T  DY   R  +
Sbjct: 61  LMGLPGAVFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEYNNNALTLPDYFTGRFED 120

Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179
             + +RI+ +  I  FF  Y  +  + G ++  + FG+  +  +       + YT +GG 
Sbjct: 121 KSRILRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGVAATILYTFIGGF 180

Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239
            +V++TDTVQA +MI  LI+ P++ +I +      +  S+     K+ ++   +L G+  
Sbjct: 181 LAVSWTDTVQASLMIFALILTPVIVIISVGG----FGDSLEVIKQKS-IENVDMLKGL-- 233

Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299
               V +I+   W  GY  G P +  RFMA     +   AR I + W I+   GA+ +G+
Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGF 290

Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353
            GIA F  +        ++ E+V   +   LF P +A + ++  +AA++ST    L++ S
Sbjct: 291 FGIAYFNEHPAVAGAVNQNAERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCS 350

Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413
           +  +E++ K ++ K+ A  ++ + V R+  + + ++A+ +A   P + +  +V Y WAG 
Sbjct: 351 SAITEDLYKAFLRKH-ASQKELVWVGRVMVLVVALVAIALA-ANPENRVLGLVSYAWAGF 408

Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453
           G  F  +V+ ++ W R         +I G L  + W   G
Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGALTVIVWKQFG 448


>gb|AAA99281.1| (L01139) proline permease [Salmonella sp.]
           Length = 489
           
 Score =  221 bits (557), Expect = 2e-56
 Identities = 132/460 (28%), Positives = 229/460 (49%), Gaps = 19/460 (4%)

Query: 1   MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60
           M   T +L     Y+  ++ +G    R  K+  D+ + GR L  +V ALS  A+  S W 
Sbjct: 1   MAISTPMLVTFCVYILGMLLIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60

Query: 61  LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119
           L+GLPG  F +G++  W AIG  LG  + W + AGRLR   E   +A+T  DY   R  +
Sbjct: 61  LMGLPGAIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFED 120

Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179
             + +RI+ +  I  FF  Y  +  + G ++  + FG+  +  +   A   + YT +GG 
Sbjct: 121 KSRVLRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGF 180

Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239
            +V++TDTVQA +MI  LI+ P++ ++ +    E         + +  ++   +L G+  
Sbjct: 181 LAVSWTDTVQASLMIFALILTPVMVIVGVGGFSE-----SLEVIKQKSIENVDMLKGL-- 233

Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299
               V +I+   W  GY  G P +  RFMA     +   AR I + W I+   GA+ +G+
Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGF 290

Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353
            GIA F  N        ++ E+V   +   LF P +A + ++  +AA++ST    L++ S
Sbjct: 291 FGIAYFNNNPALAGAVNQNSERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCS 350

Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413
           +  +E++ K ++ K+ A  ++ + V R+  + + +IA+ +A   P + +  +V Y WAG 
Sbjct: 351 SAITEDLYKAFLRKS-ASQQELVWVGRVMVLVVALIAIALA-ANPDNRVLGLVSYAWAGF 408

Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453
           G  F  +V+ ++ W R         +I G +  + W   G
Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGAVTVIVWKQYG 448


>gb|AAA99280.1| (L01138) proline permease [Salmonella sp.]
           Length = 489
           
 Score =  220 bits (556), Expect = 2e-56
 Identities = 132/460 (28%), Positives = 229/460 (49%), Gaps = 19/460 (4%)

Query: 1   MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60
           M   T +L     Y+  ++ +G    R  K+  D+ + GR L  +V ALS  A+  S W 
Sbjct: 1   MAISTPMLVTFCVYILGMLLIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60

Query: 61  LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119
           L+GLPG  F +G++  W AIG  LG  + W + AGRLR   E   +A+T  DY   R  +
Sbjct: 61  LMGLPGAIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFED 120

Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179
             + +RI+ +  I  FF  Y  +  + G ++  + FG+  +  +   A   + YT +GG 
Sbjct: 121 KSRVLRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGF 180

Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239
            +V++TDTVQA +MI  LI+ P++ ++ +    E         + +  ++   +L G+  
Sbjct: 181 LAVSWTDTVQASLMIFALILTPVMVIVGVGGFSE-----SLEVIKQKSIENVDMLKGL-- 233

Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299
               V +I+   W  GY  G P +  RFMA     +   AR I + W I+   GA+ +G+
Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHYSIVHARRISMTWMILCLAGAVAVGF 290

Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353
            GIA F  N        ++ E+V   +   LF P +A + ++  +AA++ST    L++ S
Sbjct: 291 FGIAYFNNNPALAGAVNQNSERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCS 350

Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413
           +  +E++ K ++ K+ A  ++ + V R+  + + +IA+ +A   P + +  +V Y WAG 
Sbjct: 351 SAITEDLYKAFLRKS-ASQQELVWVGRVMVLVVALIAIALA-ANPDNRVLGLVSYAWAGF 408

Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453
           G  F  +V+ ++ W R         +I G +  + W   G
Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGAVTVIVWKQYG 448


>gb|AAA99284.1| (L01142) proline permease [Salmonella sp.]
           >gi|154306|gb|AAA99285.1| (L01143) proline permease
           [Salmonella sp.]
           Length = 489
           
 Score =  220 bits (556), Expect = 2e-56
 Identities = 132/460 (28%), Positives = 229/460 (49%), Gaps = 19/460 (4%)

Query: 1   MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60
           M   T +L     Y+  ++ +G    R  K+  D+ + GR L  +V ALS  A+  S W 
Sbjct: 1   MAISTPMLVTFCVYILGMLLIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60

Query: 61  LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119
           L+GLPG  F +G++  W AIG  LG  + W + AGRLR   E   +A+T  DY   R  +
Sbjct: 61  LMGLPGAIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFED 120

Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179
             + +RI+ +  I  FF  Y  +  + G ++  + FG+  +  +   A   + YT +GG 
Sbjct: 121 KSRVLRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGF 180

Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239
            +V++TDTVQA +MI  LI+ P++ ++ +    E         + +  ++   +L G+  
Sbjct: 181 LAVSWTDTVQASLMIFALILTPVMVIVGVGGFSE-----SLEVIKQKSIENVDMLKGL-- 233

Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299
               V +I+   W  GY  G P +  RFMA     +   AR I + W I+   GA+ +G+
Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGF 290

Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353
            GIA F  N        ++ E+V   +   LF P +A V ++  +AA++ST    L++ S
Sbjct: 291 FGIAYFNNNPALAGAVNQNSERVFIELAQILFNPWVAGVLLSAILAAVMSTLSCQLLVCS 350

Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413
           +  +E++ K ++ K+ A  ++ + V R+  + + ++A+ +A   P + +  +V Y WAG 
Sbjct: 351 SAITEDLYKAFLRKS-ASQQELVWVGRVMVLVVALVAIALA-ANPDNRVLGLVSYAWAGF 408

Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453
           G  F  +V+ ++ W R         +I G +  + W   G
Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGAVTVIVWKQYG 448


>gb|AAA99286.1| (L01144) proline permease [Salmonella sp.]
           >gi|154310|gb|AAA99287.1| (L01145) proline permease
           [Salmonella sp.]
           Length = 489
           
 Score =  220 bits (556), Expect = 2e-56
 Identities = 131/460 (28%), Positives = 229/460 (49%), Gaps = 19/460 (4%)

Query: 1   MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60
           M   T +L     Y+  ++ +G    R  K+  D+ + GR L  +V ALS  A+  S W 
Sbjct: 1   MAISTPMLVTFCVYILGMLLIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60

Query: 61  LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119
           L+GLPG  F +G++  W AIG  LG  + W + AGRLR   E   +A+T  DY   R  +
Sbjct: 61  LMGLPGAIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFED 120

Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179
             + +RI+ +  I  FF  Y  +  + G ++  + FG+  +  +   A   + YT +GG 
Sbjct: 121 KSRVLRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGF 180

Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239
            +V++TDTVQA +MI  LI+ P++ ++ +    E         + +  ++   +L G+  
Sbjct: 181 LAVSWTDTVQASLMIFALILTPVMVIVGVGGFSE-----SLEVIKQKSIENVDMLKGL-- 233

Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299
               V +I+   W  GY  G P +  RFMA     +   AR I + W I+   GA+ +G+
Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGF 290

Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353
            GIA F  N        ++ E+V   +   LF P +A + ++  +AA++ST    L++ S
Sbjct: 291 FGIAYFNNNPALAGAVNQNSERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCS 350

Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413
           +  +E++ K ++ K+ A  ++ + V R+  + + ++A+ +A   P + +  +V Y WAG 
Sbjct: 351 SAITEDLYKAFLRKS-ASQQELVWVGRVMVLVVALVAIALA-ANPDNRVLGLVSYAWAGF 408

Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453
           G  F  +V+ ++ W R         +I G +  + W   G
Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGAVTVIVWKQYG 448


>gb|AAF25001.1|AF153207_2 (AF153207) proline permease [Pseudomonas putida]
           >gi|8132050|gb|AAF73192.1|AF151964_1 (AF151964) proline
           permease [Pseudomonas putida]
           Length = 492
           
 Score =  215 bits (543), Expect = 7e-55
 Identities = 134/446 (30%), Positives = 220/446 (49%), Gaps = 21/446 (4%)

Query: 12  VFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGFAFAA 71
           V Y+  ++ +G    R   +  D+ + GR L   V ALS  A+  S W L+GLPG  + A
Sbjct: 10  VIYIAAMVLIGFAAYRATNNLSDYILGGRSLGSVVTALSAGASDMSGWLLMGLPGAIYFA 69

Query: 72  GLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKY-DAVTFVDYIAKRHPEAEKWIRILGSA 130
           GL+  W AIG  +G  + W   AGRLR + E   DA+T  DY + R  +    +RI+ + 
Sbjct: 70  GLSEAWIAIGLTVGAYLNWLFVAGRLRVQTEHNGDALTLPDYFSSRFEDNSGLLRIISAI 129

Query: 131 TIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTDTVQA 190
            I  FF  Y  +  + G ++  + FG+  +  +   A   + YT +GG  +V++TDTVQA
Sbjct: 130 VILVFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIAYTFVGGFLAVSWTDTVQA 189

Query: 191 IVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAAIVFVIAEF 250
            +MI  LI+ P++ +I      + +     AA+     +   +L G    A  + +I+  
Sbjct: 190 SLMIFALILTPVIVLISTGGFDQTF-----AAIEAVNRRNFDMLKG----ATFIGIISLM 240

Query: 251 SWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGWIGIAIF----- 305
            W  GY    P +  RFMA     +   AR I + W I+   G   +G+ GIA F     
Sbjct: 241 GWGLGYF-RPPHILARFMAADSVNSIAKARRISMTWMILCLAGTCAVGFCGIAYFSAHPE 299

Query: 306 --GPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSENILKP 363
             GP   ++ ++V   +   LF P +A V ++  +AA++ T    L++ S+  +EN  K 
Sbjct: 300 LAGPVS-ENHKRVFIELAKILFNPWVAGVLLSAILAAVMITLSCQLLVCSSALTENFYKA 358

Query: 364 YIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVIVIL 423
           ++ KN A   + + V RL  +++ +IA+ MA   P + +  +V Y WAG G  F  +V++
Sbjct: 359 FLRKN-ASQVELVWVGRLMVLAVALIAIAMA-ANPENRVLGLVAYAWAGFGAAFGPVVLI 416

Query: 424 TLFWKRFHGKAVPPTIIAGLLFTVFW 449
           ++ WK          I+ G L  + W
Sbjct: 417 SVLWKGMTRNGALAGIVVGALTVILW 442


>gb|AAG19342.1| (AE005029) proline permease; PutP [Halobacterium sp. NRC-1]
           Length = 522
           
 Score =  210 bits (530), Expect = 2e-53
 Identities = 127/421 (30%), Positives = 218/421 (51%), Gaps = 19/421 (4%)

Query: 34  DFSIAGRQLPGWVAALSERATGESAWCLLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVF 93
           D+ I GR +   V   SERA+  S W  LG+PG A+  G+ A +  +G +   + AWA  
Sbjct: 6   DYVIGGRDVGPVVTGFSERASEMSGWLTLGVPGDAYTTGIMAFYNGVGMIPADLAAWAGL 65

Query: 94  AGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNT 153
           A RLRK +E   AVT   + A R  +    ++ + S  +  F   YVGAQ +  G +L  
Sbjct: 66  AKRLRKYSEIVRAVTLPTFFATRLNDDTGVVKAVSSFVLIVFEGSYVGAQIVAAGTLLRV 125

Query: 154 LFGLDPKLGMLITALVILPYTVMGGLKSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPE 213
           L G+D  +G++   ++++ YT++GG  +VA++D  Q  +++    + PI+          
Sbjct: 126 LTGVDMWVGIVAGGVIVVGYTMLGGYFAVAWSDYFQGAIILAAFAILPIIA--------- 176

Query: 214 LYAT----SVTAALSKAGVKYSTILGGMAGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMA 269
            YAT        A    G   ++I GG  G AA+  +I+  +   G + G P + +RFM 
Sbjct: 177 -YATWGLPFADLAAMDNGASLTSITGGATGWAALFGIISYAAVGLG-IPGNPHIMVRFMG 234

Query: 270 IKDDKNAKLARNIGIGWTIIAYIGALMIGWIGIAIFGPNGLKDPEQVMPSVMLKLFPPAL 329
           I   +N + A  +   +  +AYIGA ++G   +  FG  GL++ +  MP V L+L P A+
Sbjct: 235 IDRVRNVRTAAVVAQLFMFVAYIGAALVGLYALTQFG--GLENTDNAMPLVTLELLPSAV 292

Query: 330 AAVFITGAVAAMLSTADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGII 389
           A V +  A+AAM+S+ADS L+++++   E++   ++   +A   + +  SR  T+++G  
Sbjct: 293 AGVVLAAALAAMMSSADSQLLVATSAVVEDVYHGFL-NEQATEAQLVRYSRYVTLAIGFA 351

Query: 390 ALIMAYVVPSHLIYTIV-GYTWAGIGDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVF 448
           ++  AYV  +  IY +V  Y W G+G     ++I  L+W+R        +++ G    + 
Sbjct: 352 SIGFAYVARNTPIYELVLNYAWGGLGAALGPLLIAVLWWRRVTAAGAVASMVTGTATMIL 411

Query: 449 W 449
           W
Sbjct: 412 W 412


>dbj|BAB06425.1| (AP001516) proline transporter [Bacillus halodurans]
           Length = 507
           
 Score =  208 bits (525), Expect = 9e-53
 Identities = 140/449 (31%), Positives = 227/449 (50%), Gaps = 25/449 (5%)

Query: 8   LAVLVFYLGFLISVGIYQGRKAK-SHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPG 66
           +A+L+ YL  L+ +G+   +K+     DF IAGR L  W  ALS  ++G SAW +LG+ G
Sbjct: 9   VAILIAYLVALLLIGLLSSKKSSVGMTDFFIAGRNLNKWTVALSAVSSGRSAWLVLGVTG 68

Query: 67  FAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRI 126
            A+A GL A+W   G +   +  +   A R R  +E+  ++T  D +  R  +    +R 
Sbjct: 69  TAYATGLDAVWAVAGYITVEVFLFFYVARRFRAYSEQTGSITIPDILETRFNDKTHILRG 128

Query: 127 LGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTD 186
             +  I FF   YV +Q + GG    T  G+    GM +TA+++L YT++GG  +V+ TD
Sbjct: 129 GSAFIIMFFMIAYVASQLVAGGGAFATSMGVSSSTGMWVTAVILLAYTMLGGFHAVSKTD 188

Query: 187 TVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAAIVF- 245
            VQA  M ++L++ P+V +I +     L     T              GG     A  F 
Sbjct: 189 VVQAGFMFVSLVILPVVAIIGLGGFDPLLQVMHTEG------------GGFTSPFAFGFG 236

Query: 246 -VIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGWIGIAI 304
            VI      FG  G  P + +R+M++K+ K  + A  I   W ++   GA+MIG  G A 
Sbjct: 237 AVIGLLGIGFGSPGN-PHILVRYMSLKNVKEMRQAALISSVWNVLMGWGAVMIGLAGRAY 295

Query: 305 FG-----PNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSEN 359
           F      PNG  D EQV   +  ++  P      +   +AA++S+ADS L++ S+ F  +
Sbjct: 296 FPDVSLLPNG--DQEQVFLMLGSEILHPLFFGFLLVAVLAAIMSSADSQLLVGSSAFVRD 353

Query: 360 ILKPYIYKNEADPRKSLM-VSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFS 418
           I +    +N    +K L+ +SRLTTV    ++LI+A+      ++ +V + + G+G  F 
Sbjct: 354 IYQKMFRRNRKLSQKKLVRLSRLTTVVFMGLSLILAFTA-QEFVFWMVLFAFGGLGACFG 412

Query: 419 VIVILTLFWKRFHGKAVPPTIIAGLLFTV 447
             ++L+ +WK    + V   +IAGLL  +
Sbjct: 413 PALLLSFYWKGVTRQGVLWGMIAGLLTVI 441


>sp|P45174|PUTP_HAEIN SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE) >gi|1075316|pir||E64118
           sodium/proline symporter - Haemophilus influenzae
           (strain Rd KW20) >gi|1574814|gb|AAC22999.1| (U32814)
           sodium/proline symporter (proline permease) (putP)
           [Haemophilus influenzae Rd]
           Length = 504
           
 Score =  207 bits (522), Expect = 2e-52
 Identities = 131/488 (26%), Positives = 238/488 (47%), Gaps = 20/488 (4%)

Query: 8   LAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGF 67
           L     Y+  ++ +G+       +  D+ + GR+L  +V A+S  A+  S W L+GLPG 
Sbjct: 8   LITFTIYIFGMLLIGVLAYYYTNNLSDYILGGRRLGSFVTAMSAGASDMSGWLLMGLPGA 67

Query: 68  AFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPEAEKWIRI 126
            + +GL   W AIG  +G    W + AGRLR   E   +A+T  +Y   R   + K +++
Sbjct: 68  VYLSGLVEGWIAIGLTIGAYFNWLLVAGRLRVYTELNNNALTLPEYFHNRFGSSHKLLKL 127

Query: 127 LGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTD 186
           + +  I  F   Y  +  + G K+   +F ++    +   A   + YT +GG  +V++TD
Sbjct: 128 VSATIILVFLTIYCASGVVAGAKLFQNIFSVEYSTALWYGAAATIAYTFIGGFLAVSWTD 187

Query: 187 TVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAAIVFV 246
           T+QA +MI  LI+ P+  ++  A+         +A L +A    +     +  +   + +
Sbjct: 188 TIQATLMIFALILTPVFVLLSFAD-----TAQFSAVLEQAEAAVNKDFTDLFTSTTPLGL 242

Query: 247 IAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGWIGIAIFG 306
           ++  +W  GY  G P +  RFMA    K+   AR I +GW ++   GA+ IG   I  F 
Sbjct: 243 LSLAAWGLGYF-GQPHILARFMAADSVKSLIKARRISMGWMVLCLAGAIGIGLFAIPYFF 301

Query: 307 PNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSENI 360
            N        ++PEQV   +   LF P +A + ++  +AA++ST  + L++SS+  +E+ 
Sbjct: 302 ANPAIAGTVNREPEQVFIELAKLLFNPWIAGILLSAILAAVMSTLSAQLLISSSSITEDF 361

Query: 361 LKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVI 420
            K +I  N A  ++ + + R+  + +  +A+ +A    S ++  +V + WAG G  F  +
Sbjct: 362 YKGFIRPN-ASEKELVWLGRIMVLVIAALAIWIAQDENSKVL-KLVEFAWAGFGSAFGPV 419

Query: 421 VILTLFWKRFHGKAVPPTIIAGLLFTVFW---ISSGLD-AKVSVRLMNF-IVTFIVAIIA 475
           V+ +LFWKR         ++ G +    W   + +  D  KV   +  F   +  + +I+
Sbjct: 420 VLFSLFWKRMTSSGAMAGMLVGAVTVFAWKEVVPADTDWFKVYEMIPGFAFASLAIIVIS 479

Query: 476 TYAIKPEK 483
             + KPE+
Sbjct: 480 LLSNKPEQ 487


>gi|11498674 pantothenate permease (panF-1) [Archaeoglobus fulgidus]
           >gi|7442768|pir||E69383 pantothenate permease (panF-1)
           homolog - Archaeoglobus fulgidus
           >gi|2649519|gb|AAB90171.1| (AE001029) pantothenate
           permease (panF-1) [Archaeoglobus fulgidus]
           Length = 491
           
 Score =  170 bits (426), Expect = 4e-41
 Identities = 133/461 (28%), Positives = 231/461 (49%), Gaps = 29/461 (6%)

Query: 7   ILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPG 66
           I AVL+ YL  ++ +GIY+ RK +   D+ +AG++L   V + S  AT  S    LG  G
Sbjct: 3   IEAVLIGYLAVVLLIGIYEYRKTRGLLDYYLAGKKLGTLVVSFSFFATYFSTAAFLGGGG 62

Query: 67  FAFAAGLAAIWPAIGC---VLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKW 123
             F  G    W A      VL  I+AW V A  +++ A++Y A+T  +   KR   A  +
Sbjct: 63  TGFLLGFQ--WSAFLTFFHVLFAILAWMVIAPPMKRIADEYGALTIPELFRKR---AGVF 117

Query: 124 IRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVA 183
            +I+ +  I FFF  Y+ + Y G G +L  +  +D   G++ITA++++ YT +GG ++V 
Sbjct: 118 SQIVAAVVIIFFFELYMVSIYKGAGNLLQVMLSMDYTTGLVITAVIVMVYTAIGGFRAVV 177

Query: 184 YTDTVQAIVMI-------LTLI--VAPIVGVIYIANHPELYATSVTAALSKAGVKYSTIL 234
            TD +Q ++++       LTLI  +      I   ++ +++   V  AL + G K     
Sbjct: 178 MTDLIQGVIVLIGGVALFLTLIYSLGGFSSAIEALSNAKIFGEMVGKALFEIG-KVGPPP 236

Query: 235 GGMAGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDK---NAKLARNIGIGWTIIAY 291
              AG      +   F+     L   PQL +RF+A +D +   N  +   + IG   I  
Sbjct: 237 IVKAGMIVPFVLSLTFAISVAQLAS-PQLVVRFVAARDSRVIANGMILTPLIIGIFAICV 295

Query: 292 IGALMIGWIGIAIFGPN---GLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSL 348
                 GW+ I  +  +    LKD + V+P + +KLFP  + A+ +T  +AA +ST +SL
Sbjct: 296 FSIGPFGWLVIPKYTDDVTQFLKDVDLVVPFIAMKLFPAGINALLLTAIIAAAMSTINSL 355

Query: 349 LILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGY 408
           + L +T F  ++++      + + R +L ++R        I +I A + P  +I  IVG 
Sbjct: 356 IHLVATAFVRDLVQNV---KKIEERTALNLTRFAVFIFATIPVIFA-INPMGVIVEIVGV 411

Query: 409 TWAGIGDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFW 449
           +++ I   F V +I  L+ ++ +  A+  +++A +L +V W
Sbjct: 412 SFSVITSAFLVPLIACLYSEKPNSAAISASMVAAVLASVLW 452


>sp|P44963|PANF_HAEIN SODIUM/PANTOTHENATE SYMPORTER (PANTOTHENATE PERMEASE)
           >gi|1075105|pir||H64105 pantothenate transport protein -
           Haemophilus influenzae  (strain Rd KW20)
           >gi|1574003|gb|AAC22634.1| (U32778) sodium/pantothenate
           symporter (panF) [Haemophilus influenzae Rd]
           Length = 484
           
 Score =  152 bits (379), Expect = 1e-35
 Identities = 128/467 (27%), Positives = 223/467 (47%), Gaps = 30/467 (6%)

Query: 7   ILAVLVFYLGFLISVGIY---QGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLG 63
           I+  L+ YL F+    I+   +  K     ++ +  R + G+V A++  +T  SA   +G
Sbjct: 5   IILPLIIYLTFVFGAAIFAYVKRTKGDFLTEYYVGNRSMTGFVLAMTTASTYASASSFVG 64

Query: 64  LPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKW 123
            PG A+  GL  +  A+  V  + +A      +    + + +A+T  D    R+    K+
Sbjct: 65  GPGAAYKYGLGWVLLAMIQVPVVWLALGALGKKFALLSRETNALTINDLFFYRYKN--KY 122

Query: 124 IRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVA 183
           +  L S  +   FF  +  Q++GG ++L T  G+     +L+ AL +  YT +GG ++V 
Sbjct: 123 LVWLSSLALLLAFFAAMTVQFIGGARLLETTIGISYTQALLLFALTVGIYTFIGGFRAVV 182

Query: 184 YTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAAI 243
            TDT+Q  VMI   I+  ++G IY     E     +T         Y     G  G    
Sbjct: 183 LTDTIQGTVMIFGTIIL-LIGTIYALGGVESAVNKLTEIDPDLVTPY-----GPNGMLDF 236

Query: 244 VFVIAEFSWFFGYLG--GMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGWIG 301
            F +A F W     G  G+P  ++R MA KD K       IG     I  +G  + G +G
Sbjct: 237 QF-MASF-WILVCFGVVGLPHTAVRCMAFKDSKALHRGMLIGTIVLSIIMLGMHLAGALG 294

Query: 302 IAIFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSENI- 360
            A+  PN L   +QV+P++M+K+ PP +A +F+   ++A++ST D+ LI SS+ F +++ 
Sbjct: 295 RAVI-PN-LTVSDQVIPTLMIKVLPPIVAGIFLAAPMSAIMSTIDAQLIQSSSIFVKDLY 352

Query: 361 --LKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFS 418
              KP   KNE   +K    S + T+ L  + LI A + P  +I  +  + + G+   F 
Sbjct: 353 LSAKPEAAKNE---KKVSYFSSIITLILTAL-LIFAALNPPDMIIWLNLFAFGGLEAAFL 408

Query: 419 VIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSGLDAKVSVRLMNF 465
            +++L ++W + +      ++I GL   +      L  ++ ++L NF
Sbjct: 409 WVIVLGIYWDKANAYGALSSMIIGLGSYI------LLTQLGIKLFNF 449


>pir||D65118 pantothenate permease [validated] - Escherichia coli
           >gi|606198|gb|AAA58061.1| (U18997) pantothenate permease
           [Escherichia coli] >gi|1789656|gb|AAC76290.1| (AE000404)
           sodium/pantothenate symporter [Escherichia coli K12]
           Length = 485
           
 Score =  144 bits (360), Expect = 2e-33
 Identities = 123/463 (26%), Positives = 233/463 (49%), Gaps = 39/463 (8%)

Query: 1   MEARTQILAVLVFYLGFLISVGIYQGRKAKSH---KDFSIAGRQLPGWVAALSERATGES 57
           M  + +++  LV YL  +  + +Y  RK  +     ++ +  R + G V A++  AT  S
Sbjct: 1   MTMQLEVILPLVAYLVVVFGISVYAMRKRSTGTFLNEYFLGSRSMGGIVLAMTLTATYIS 60

Query: 58  AWCLLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRH 117
           A   +G PG A+  GL  +  A+  +  + ++  +   +    A +Y+AVT  D +  R+
Sbjct: 61  ASSFIGGPGAAYKYGLGWVLLAMIQLPAVWLSLGILGKKFAILARRYNAVTLNDMLFARY 120

Query: 118 PEAEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMG 177
               + +  L S ++   F   +  Q++GG ++L T  G+  + G+LI  + I  YT  G
Sbjct: 121 QS--RLLVWLASLSLLVAFVGAMTVQFIGGARLLETAAGIPYETGLLIFGISIALYTAFG 178

Query: 178 GLKSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTI---L 234
           G ++    DT+Q +VM++  +V  ++GV++ A             LS A     TI   L
Sbjct: 179 GFRASVLNDTMQGLVMLIGTVVL-LIGVVHAA-----------GGLSNAVQTLQTIDPQL 226

Query: 235 GGMAGAAAIVFVIAEFSWF----FGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIA 290
               GA  I+      S++    FG + G+P  ++R ++ KD K   + R I IG  ++A
Sbjct: 227 VTPQGADDILSPAFMTSFWVLVCFGVI-GLPHTAVRCISYKDSK--AVHRGIIIGTIVVA 283

Query: 291 YI--GALMIGWIGIAIFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSL 348
            +  G  + G +G A+     L  P+ V+P++M+K+ PP  A +F+   +AA++ST ++ 
Sbjct: 284 ILMFGMHLAGALGRAVI--PDLTVPDLVIPTLMVKVLPPFAAGIFLAAPMAAIMSTINAQ 341

Query: 349 LILSSTEFSENI---LKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTI 405
           L+ SS    +++   ++P   +NE   ++   +S + T+ LG + L+ A+  P  +I+  
Sbjct: 342 LLQSSATIIKDLYLNIRPDQMQNETRLKR---MSAVITLVLGALLLLAAWKPPEMIIWLN 398

Query: 406 VGYTWAGIGDTFSVIVILTLFWKRFHGK-AVPPTIIAGLLFTV 447
           +   + G+   F   ++L L+W+R + K A+   I+ G+L+ V
Sbjct: 399 L-LAFGGLEAVFLWPLVLGLYWERANAKGALSAMIVGGVLYAV 440


>sp|P16256|PANF_ECOLI SODIUM/PANTOTHENATE SYMPORTER (PANTOTHENATE PERMEASE)
           Length = 483
           
 Score =  143 bits (357), Expect = 4e-33
 Identities = 122/458 (26%), Positives = 231/458 (49%), Gaps = 39/458 (8%)

Query: 6   QILAVLVFYLGFLISVGIYQGRKAKSH---KDFSIAGRQLPGWVAALSERATGESAWCLL 62
           +++  LV YL  +  + +Y  RK  +     ++ +  R + G V A++  AT  SA   +
Sbjct: 4   EVILPLVAYLVVVFGISVYAMRKRSTGTFLNEYFLGSRSMGGIVLAMTLTATYISASSFI 63

Query: 63  GLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEK 122
           G PG A+  GL  +  A+  +  + ++  +   +    A +Y+AVT  D +  R+    +
Sbjct: 64  GGPGAAYKYGLGWVLLAMIQLPAVWLSLGILGKKFAILARRYNAVTLNDMLFARYQS--R 121

Query: 123 WIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSV 182
            +  L S ++   F   +  Q++GG ++L T  G+  + G+LI  + I  YT  GG ++ 
Sbjct: 122 LLVWLASLSLLVAFVGAMTVQFIGGARLLETAAGIPYETGLLIFGISIALYTAFGGFRAS 181

Query: 183 AYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTI---LGGMAG 239
              DT+Q +VM++  +V  ++GV++ A             LS A     TI   L    G
Sbjct: 182 VLNDTMQGLVMLIGTVVL-LIGVVHAA-----------GGLSNAVQTLQTIDPQLVTPQG 229

Query: 240 AAAIVFVIAEFSWF----FGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYI--G 293
           A  I+      S++    FG + G+P  ++R ++ KD K   + R I IG  ++A +  G
Sbjct: 230 ADDILSPAFMTSFWVLVCFGVI-GLPHTAVRCISYKDSK--AVHRGIIIGTIVVAILMFG 286

Query: 294 ALMIGWIGIAIFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353
             + G +G A+     L  P+ V+P++M+K+ PP  A +F+   +AA++ST ++ L+ SS
Sbjct: 287 MHLAGALGRAVI--PDLTVPDLVIPTLMVKVLPPFAAGIFLAAPMAAIMSTINAQLLQSS 344

Query: 354 TEFSENI---LKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTW 410
               +++   ++P   +NE   ++   +S + T+ LG + L+ A+  P  +I+  +   +
Sbjct: 345 ATIIKDLYLNIRPDQMQNETRLKR---MSAVITLVLGALLLLAAWKPPEMIIWLNL-LAF 400

Query: 411 AGIGDTFSVIVILTLFWKRFHGK-AVPPTIIAGLLFTV 447
            G+   F   ++L L+W+R + K A+   I+ G+L+ V
Sbjct: 401 GGLEAVFLWPLVLGLYWERANAKGALSAMIVGGVLYAV 438


>pir||C69115 sodium/proline symporter (proline permease) - Methanobacterium
           thermoautotrophicum (strain Delta H)
           >gi|2622992|gb|AAB86322.1| (AE000938) sodium/proline
           symporter (proline permease) [Methanobacterium
           thermoautotrophicum]
           Length = 526
           
 Score =  137 bits (342), Expect = 3e-31
 Identities = 106/468 (22%), Positives = 216/468 (45%), Gaps = 41/468 (8%)

Query: 8   LAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGF 67
           + VL+++L  +  VG    R+ ++ +D+ +AGR+   ++ A+S  AT  S   ++G  G 
Sbjct: 8   IVVLIYFL-LVGYVGYVAWRRTETSEDYMVAGRRTHPYIMAMSYGATFISTAAIVGFGGM 66

Query: 68  AFAAGLAAIWPA-IGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRI 126
           A   G+  +W   +  ++GI +A+  F  R  K      A+TF +++ +R     ++++ 
Sbjct: 67  AGVFGMGILWLVFLNILVGIFIAFVFFGKRTMKMGHNMSALTFPEFLGRRFNS--RFLQY 124

Query: 127 LGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTD 186
            G A I      Y     +G  + + T  GLD  + +++ A+++  Y V+GG++ V YTD
Sbjct: 125 FGGAIIFLGMPLYASVVLIGAARFIETTLGLDFSIALILMAVIVAVYVVLGGIRGVMYTD 184

Query: 187 TVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAAIVFV 246
            +Q  +M L +I   +V   Y+         ++T        K   I  G  G  ++   
Sbjct: 185 ALQGTIMFLGMIFL-VVSTYYLLGGVVDAHQALTNISHLIPAKARAI--GATGWTSMPLY 241

Query: 247 IAEFSWFF----------GYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTII------A 290
            + + W            G L   PQL +RFM +K   N +L R + IG   I      A
Sbjct: 242 GSPYWWTLLSTIILGVGVGVLA-QPQLIVRFMTVKS--NRELNRGVLIGALFIFVMTWSA 298

Query: 291 YI-GALM-------IGWIGIAIFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAML 342
           Y+ GAL        +G I +   G N     ++++P  +    P   + +F+   ++A +
Sbjct: 299 YVVGALSNVYFFRKMGMIAVQAAGGNA----DKIIPFFIKSAMPEWFSYIFMLTLLSAAM 354

Query: 343 STADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLI 402
           ST  +   +  T    ++ +  + + + D  +S++++R   +   +IA+++ Y++P  ++
Sbjct: 355 STLSAQFHVQGTAIGRDVYET-VRRRKGD--RSVLITRGGIIIAVLIAVVLGYLLPGSIV 411

Query: 403 YTIVGYTWAGIGDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWI 450
                  +     +F  + +  +FWKR   +     +++G + ++FW+
Sbjct: 412 AQGTALFFGICAASFLSVYVAAIFWKRATRQGAIAGMVSGAIVSLFWL 459


>gb|AAF45280.1| (AF230619) proline permease [Escherichia coli]
           Length = 232
           
 Score =  135 bits (336), Expect = 1e-30
 Identities = 79/239 (33%), Positives = 125/239 (52%), Gaps = 11/239 (4%)

Query: 32  HKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGFAFAAGLAAIWPAIGCVLGIIVAWA 91
           H D+ + GR L  +V ALS  A+  S W L+GLPG  F +G++  W AIG  LG  + W 
Sbjct: 1   HDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGAVFLSGISESWIAIGLTLGAWINWK 60

Query: 92  VFAGRLRKEAE-KYDAVTFVDYIAKRHPEAEKWIRILGSATIAFFFFFYVGAQYLGGGKV 150
           + AGRLR   E   +A+T  DY   R  +  + +RI+ +  I  FF  Y  +  + G ++
Sbjct: 61  LVAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARL 120

Query: 151 LNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTDTVQAIVMILTLIVAPIVGVIYIAN 210
             + FG+  +  +   A   + YT +GG  +V++TDTVQA +MI  LI+ P++ +I +  
Sbjct: 121 FESTFGMSYETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGG 180

Query: 211 HPELYATSVTAALSKAGVKYSTILGGMAGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMA 269
               +  S+     K+ ++   +L G+      V +I+   W  GY  G P +  RFMA
Sbjct: 181 ----FGDSLEVIKQKS-IENVDMLKGL----NFVAIISLMGWGLGYF-GQPHILARFMA 229


>gb|AAF45283.1| (AF230622) proline permease [Escherichia coli]
           Length = 232
           
 Score =  132 bits (330), Expect = 6e-30
 Identities = 78/239 (32%), Positives = 125/239 (51%), Gaps = 11/239 (4%)

Query: 32  HKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGFAFAAGLAAIWPAIGCVLGIIVAWA 91
           + D+ + GR L  +V ALS  A+  S W L+GLPG  F +G++  W AIG  LG  + W 
Sbjct: 1   YDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGAVFLSGISESWIAIGLTLGAWINWK 60

Query: 92  VFAGRLRKEAE-KYDAVTFVDYIAKRHPEAEKWIRILGSATIAFFFFFYVGAQYLGGGKV 150
           + AGRLR   E   +A+T  DY   R  +  + +RI+ +  I  FF  Y  +  + G ++
Sbjct: 61  LVAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARL 120

Query: 151 LNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTDTVQAIVMILTLIVAPIVGVIYIAN 210
             + FG+  +  +   A   + YT +GG  +V++TDTVQA +MI  LI+ P++ +I +  
Sbjct: 121 FESTFGMSYETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGG 180

Query: 211 HPELYATSVTAALSKAGVKYSTILGGMAGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMA 269
               +  S+     K+ ++   +L G+      V +I+   W  GY  G P +  RFMA
Sbjct: 181 ----FGDSLEVIKQKS-IENVDMLKGL----NFVAIISLMGWGLGYF-GQPHILARFMA 229


>gb|AAF45263.1| (AF230602) proline permease [Escherichia coli]
           >gi|7288753|gb|AAF45265.1| (AF230604) proline permease
           [Escherichia coli] >gi|7288757|gb|AAF45267.1| (AF230606)
           proline permease [Escherichia coli]
           >gi|7288765|gb|AAF45271.1| (AF230610) proline permease
           [Escherichia coli] >gi|7288769|gb|AAF45273.1| (AF230612)
           proline permease [Escherichia coli]
           >gi|7288771|gb|AAF45274.1| (AF230613) proline permease
           [Escherichia coli] >gi|7288773|gb|AAF45275.1| (AF230614)
           proline permease [Escherichia coli]
           >gi|7288775|gb|AAF45276.1| (AF230615) proline permease
           [Escherichia coli] >gi|7288777|gb|AAF45277.1| (AF230616)
           proline permease [Escherichia coli]
           >gi|7288779|gb|AAF45278.1| (AF230617) proline permease
           [Escherichia coli] >gi|7288781|gb|AAF45279.1| (AF230618)
           proline permease [Escherichia coli]
           >gi|7288785|gb|AAF45281.1| (AF230620) proline permease
           [Escherichia coli] >gi|7288787|gb|AAF45282.1| (AF230621)
           proline permease [Escherichia coli]
           >gi|7288791|gb|AAF45284.1| (AF230623) proline permease
           [Escherichia coli] >gi|7288797|gb|AAF45287.1| (AF230626)
           proline permease [Escherichia coli]
           >gi|7288799|gb|AAF45288.1| (AF230627) proline permease
           [Escherichia coli] >gi|7288801|gb|AAF45289.1| (AF230628)
           proline permease [Escherichia coli]
           >gi|7288803|gb|AAF45290.1| (AF230629) proline permease
           [Escherichia coli] >gi|7288805|gb|AAF45291.1| (AF230630)
           proline permease [Escherichia coli]
           >gi|7288807|gb|AAF45292.1| (AF230631) proline permease
           [Escherichia coli] >gi|7288809|gb|AAF45293.1| (AF230632)
           proline permease [Escherichia coli]
           >gi|7288811|gb|AAF45294.1| (AF230633) proline permease
           [Escherichia coli] >gi|7288813|gb|AAF45295.1| (AF230634)
           proline permease [Escherichia coli]
           >gi|7288815|gb|AAF45296.1| (AF230635) proline permease
           [Escherichia coli]
           Length = 232
           
 Score =  132 bits (329), Expect = 8e-30
 Identities = 78/237 (32%), Positives = 124/237 (51%), Gaps = 11/237 (4%)

Query: 34  DFSIAGRQLPGWVAALSERATGESAWCLLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVF 93
           D+ + GR L  +V ALS  A+  S W L+GLPG  F +G++  W AIG  LG  + W + 
Sbjct: 3   DYILGGRSLGPFVTALSAGASDMSGWLLMGLPGAVFLSGISESWIAIGLTLGAWINWKLV 62

Query: 94  AGRLRKEAE-KYDAVTFVDYIAKRHPEAEKWIRILGSATIAFFFFFYVGAQYLGGGKVLN 152
           AGRLR   E   +A+T  DY   R  +  + +RI+ +  I  FF  Y  +  + G ++  
Sbjct: 63  AGRLRVHTEYNNNALTLPDYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARLFE 122

Query: 153 TLFGLDPKLGMLITALVILPYTVMGGLKSVAYTDTVQAIVMILTLIVAPIVGVIYIANHP 212
           + FG+  +  +   A   + YT +GG  +V++TDTVQA +MI  LI+ P++ +I +    
Sbjct: 123 STFGMSYETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGG-- 180

Query: 213 ELYATSVTAALSKAGVKYSTILGGMAGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMA 269
             +  S+     K+ ++   +L G+      V +I+   W  GY  G P +  RFMA
Sbjct: 181 --FGDSLEVIKQKS-IENVDMLKGL----NFVAIISLMGWGLGYF-GQPHILARFMA 229


>gb|AAF45264.1| (AF230603) proline permease [Escherichia coli]
           >gi|7288755|gb|AAF45266.1| (AF230605) proline permease
           [Escherichia coli] >gi|7288759|gb|AAF45268.1| (AF230607)
           proline permease [Escherichia coli]
           >gi|7288761|gb|AAF45269.1| (AF230608) proline permease
           [Escherichia coli] >gi|7288763|gb|AAF45270.1| (AF230609)
           proline permease [Escherichia coli]
           >gi|7288767|gb|AAF45272.1| (AF230611) proline permease
           [Escherichia coli]
           Length = 232
           
 Score =  132 bits (329), Expect = 8e-30
 Identities = 78/237 (32%), Positives = 124/237 (51%), Gaps = 11/237 (4%)

Query: 34  DFSIAGRQLPGWVAALSERATGESAWCLLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVF 93
           D+ + GR L  +V ALS  A+  S W L+GLPG  F +G++  W AIG  LG  + W + 
Sbjct: 3   DYILGGRSLGPFVTALSAGASDMSGWLLMGLPGAVFLSGISESWIAIGLTLGAWINWKLV 62

Query: 94  AGRLRKEAE-KYDAVTFVDYIAKRHPEAEKWIRILGSATIAFFFFFYVGAQYLGGGKVLN 152
           AGRLR   E   +A+T  DY   R  +  + +RI+ +  I  FF  Y  +  + G ++  
Sbjct: 63  AGRLRVHTEYNNNALTLPDYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARLFE 122

Query: 153 TLFGLDPKLGMLITALVILPYTVMGGLKSVAYTDTVQAIVMILTLIVAPIVGVIYIANHP 212
           + FG+  +  +   A   + YT +GG  +V++TDTVQA +MI  LI+ P++ +I +    
Sbjct: 123 STFGMSYETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGG-- 180

Query: 213 ELYATSVTAALSKAGVKYSTILGGMAGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMA 269
             +  S+     K+ ++   +L G+      V +I+   W  GY  G P +  RFMA
Sbjct: 181 --FGDSLEVIKQKS-IENVDMLKGL----NFVAIISLMGWGLGYF-GQPHILARFMA 229


>gb|AAF45285.1| (AF230624) proline permease [Escherichia coli]
           Length = 232
           
 Score =  132 bits (329), Expect = 8e-30
 Identities = 78/237 (32%), Positives = 124/237 (51%), Gaps = 11/237 (4%)

Query: 34  DFSIAGRQLPGWVAALSERATGESAWCLLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVF 93
           D+ + GR L  +V ALS  A+  S W L+GLPG  F +G++  W AIG  LG  + W + 
Sbjct: 3   DYILGGRSLGPFVTALSAGASDMSGWLLMGLPGAVFLSGISESWIAIGLTLGAWINWKLV 62

Query: 94  AGRLRKEAE-KYDAVTFVDYIAKRHPEAEKWIRILGSATIAFFFFFYVGAQYLGGGKVLN 152
           AGRLR   E   +A+T  DY   R  +  + +RI+ +  I  FF  Y  +  + G ++  
Sbjct: 63  AGRLRVHTEYNNNALTLPDYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARLFE 122

Query: 153 TLFGLDPKLGMLITALVILPYTVMGGLKSVAYTDTVQAIVMILTLIVAPIVGVIYIANHP 212
           + FG+  +  +   A   + YT +GG  +V++TDTVQA +MI  LI+ P++ +I +    
Sbjct: 123 STFGMSYETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGG-- 180

Query: 213 ELYATSVTAALSKAGVKYSTILGGMAGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMA 269
             +  S+     K+ ++   +L G+      V +I+   W  GY  G P +  RFMA
Sbjct: 181 --FGDSLEVIKQKS-IENVDMLKGL----NFVAIISLMGWGMGYF-GQPHILARFMA 229


>gb|AAF45286.1| (AF230625) proline permease [Escherichia coli]
           Length = 232
           
 Score =  130 bits (323), Expect = 4e-29
 Identities = 77/237 (32%), Positives = 124/237 (51%), Gaps = 11/237 (4%)

Query: 34  DFSIAGRQLPGWVAALSERATGESAWCLLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVF 93
           D+ + GR L  +V ALS  A+  S W L+GLPG  F +G++  W AIG  LG  + W + 
Sbjct: 3   DYILGGRSLGPFVTALSVGASDMSGWLLMGLPGAVFLSGISESWIAIGLTLGAWINWKLV 62

Query: 94  AGRLRKEAE-KYDAVTFVDYIAKRHPEAEKWIRILGSATIAFFFFFYVGAQYLGGGKVLN 152
           AGRLR   E   +A+T  +Y   R  +  + +RI+ +  I  FF  Y  +  + G ++  
Sbjct: 63  AGRLRVHTEYNNNALTLPNYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARLFE 122

Query: 153 TLFGLDPKLGMLITALVILPYTVMGGLKSVAYTDTVQAIVMILTLIVAPIVGVIYIANHP 212
           + FG+  +  +   A   + YT +GG  +V++TDTVQA +MI  LI+ P++ +I +    
Sbjct: 123 STFGMSYETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGG-- 180

Query: 213 ELYATSVTAALSKAGVKYSTILGGMAGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMA 269
             +  S+     K+ ++   +L G+      V +I+   W  GY  G P +  RFMA
Sbjct: 181 --FGDSLEVIKQKS-IENVDMLKGL----NFVAIISLMGWGLGYF-GQPHILARFMA 229


>pir||E70201 pantothenate permease (panF) homolog - Lyme disease spirochete
           >gi|2688763|gb|AAC67168.1| (AE001180) pantothenate
           permease (panF) [Borrelia burgdorferi]
           Length = 444
           
 Score =  127 bits (317), Expect = 2e-28
 Identities = 106/425 (24%), Positives = 208/425 (48%), Gaps = 22/425 (5%)

Query: 35  FSIAGRQLPGWVAALSERATGESAWCLLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFA 94
           + +A R +   V AL   ++  SA   +  P   +  GL+ I  A   +   ++ + +  
Sbjct: 6   YFLANRNINFIVMALLFSSSYISASSFISGPSAVYKYGLSFILLATIQIPTTLIVFIIVG 65

Query: 95  GRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTL 154
            RL +E++K +A+  +DYI  RH     ++ ++    + FF  F + AQ +GG K++   
Sbjct: 66  QRLNRESKKINAINIIDYI--RHRYESDFLALMSGFVLIFFSMFLISAQLIGGAKLIEVF 123

Query: 155 FGLDPKLGMLITALVILPYTVMGGLKSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPEL 214
           +G+D  +G+   A ++  Y   GG K+VAYTD +Q  +M+++ ++     +        L
Sbjct: 124 WGIDYVVGLTFFAFLVFIYVFFGGFKAVAYTDLIQGFLMLVSSVILFSKMLDLGGGINNL 183

Query: 215 YATSVTAALSKAGVKYSTILGGMAGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDK 274
           + T+ T++L K     S +L   A       +        G L G PQ+   F+A KD+ 
Sbjct: 184 FKTA-TSSLDK-----SLLLPSNADLKPQYIISFWILIGIGIL-GQPQIINNFIAFKDEN 236

Query: 275 NAKLARNIGIGWTIIAYIGALM--IGWIGIAIFGPNGLKDPEQVMPSVMLKLFPPALAAV 332
             K   ++ I   II+++  LM  IG+  I +F    L   ++V+ +V LK+  P    +
Sbjct: 237 AIKF--SLPISTFIISFLIVLMHLIGFFAIILF--PDLSPNDKVVLNVALKVLNPFSCFM 292

Query: 333 FITGAVAAMLSTADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVS--LGIIA 390
           F  G ++A++ST DS L+L ++   ++I   +IYK   D ++ + + R+  +S    I+ 
Sbjct: 293 FFIGLLSAIMSTVDSNLLLITSVLIKSI---FIYKE--DLKEDVKIGRIIMISNIFFILI 347

Query: 391 LIMAYVVPSHLIYTIVGYTWAGIGDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWI 450
           +++  + P + ++ I  + +  +  +F  I++  L+       A   ++  GL+F +  +
Sbjct: 348 ILIFSLFPPNFLFFINIFAFGALEVSFFPIIVFGLYLNFVSKIAAFASMFLGLIFYLSIL 407

Query: 451 SSGLD 455
             GL+
Sbjct: 408 FFGLN 412


>sp|P39599|YWCA_BACSU HYPOTHETICAL 55.0 KD PROTEIN IN EPR-GALK INTERGENIC REGION
           >gi|7442759|pir||S39686 Na+-dependent symport homolog
           ywcA - Bacillus subtilis >gi|580869|emb|CAA51587.1|
           (X73124) ipa-31r [Bacillus subtilis]
           >gi|2636359|emb|CAB15850.1| (Z99123) alternate gene
           name: ipa-31r~similar to Na+-dependent symport [Bacillus
           subtilis]
           Length = 516
           
 Score =  120 bits (299), Expect = 3e-26
 Identities = 107/441 (24%), Positives = 203/441 (45%), Gaps = 30/441 (6%)

Query: 23  IYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGFAFAAGLAAIWPAIGC 82
           ++  ++ K+  +F  AG  L G    L+      SA   LG+ G     G    + +IG 
Sbjct: 24  VFCAKRTKTTSEFYTAGGGLTGVQNGLAIAGDYMSAASFLGIAGMIALYGFDGFFYSIGF 83

Query: 83  VLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRILGSATIAFFFFFYVGA 142
           ++  +V   + A  LR    KY   T  D IA R  E  K IR + +        FY+ A
Sbjct: 84  LVAYLVVLYIVAEPLRNLG-KY---TMADMIAARFKE--KKIRGVAALNTIAISTFYMIA 137

Query: 143 QYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTDTVQAIVMIL-TLIVAP 201
           Q +G G ++  L GLD    +LI  +++  Y V GG+ + ++   ++A++++  TL+++ 
Sbjct: 138 QLVGAGALIKLLLGLDYTAAVLIVGVLMTIYVVFGGMIATSWVQIIKAVLLMAGTLVISI 197

Query: 202 IVGVIYIANHPELY-----ATSVTAALSKAGVKYSTILGGMAGAAAIVFVIAEFSWFFGY 256
           IV   +  +   ++     AT + A     G KY   L  ++   A+V   A        
Sbjct: 198 IVFSKFGFSLNTMFEQMKTATPLGADFLNPGNKYKVPLETLSLNLALVLGTA-------- 249

Query: 257 LGGMPQLSIRFMAIKDDKNAKLARNIGIGWTI-IAYIGALMIGWIGIAIFGPNGLKDPEQ 315
             G+P + IRF  +KD K A+ +  +   W I + YI  + +G+   A  G + +   +Q
Sbjct: 250 --GLPHILIRFYTVKDAKTARTSV-VSATWIIGVFYIMTVFLGFGAAAFVGFDAITAADQ 306

Query: 316 VMPSVMLKLFPPALAAVFITGAVAAM-----LSTADSLLILSSTEFSENILKPYIYKNEA 370
              ++   L   AL   F+   V+A+     L+    L++ +++ F+ +I    I K EA
Sbjct: 307 A-GNMAAPLLAKALGGDFLFAFVSAIAFATILAVVTGLVLSAASAFAHDIYSQIIRKGEA 365

Query: 371 DPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVIVILTLFWKRF 430
             ++ +  +R  +V++ ++++++A    S  +  +V   +A        +++ T+FWKRF
Sbjct: 366 TEKEQMKAARWASVAVSVLSILLAIFAQSLNVAFLVALAFAVAASANLPLIVFTVFWKRF 425

Query: 431 HGKAVPPTIIAGLLFTVFWIS 451
           +        + GL+  +  +S
Sbjct: 426 NASGALWGSLTGLISALVLVS 446


>pir||JU0296 pantothenate permease - Escherichia coli >gi|147067|gb|AAA24276.1|
           (M30953) pantothenate permease (panF) [Escherichia coli]
           Length = 482
           
 Score =  118 bits (292), Expect = 2e-25
 Identities = 115/458 (25%), Positives = 217/458 (47%), Gaps = 40/458 (8%)

Query: 6   QILAVLVFYLGFLISVGIYQGRKAKSH---KDFSIAGRQLPGWVAALSERATGESAWCLL 62
           +++  LV YL  +  + +Y  RK  +     ++ +  R + G V A++  AT  SA   +
Sbjct: 4   EVILPLVAYLVVVFGISVYAMRKRSTGTFLNEYFLGSRSMGGIVLAMTLTATYISASSFI 63

Query: 63  GLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEK 122
           G PG A+  GL  +  A+  +  + ++  +   +    A +Y+AVT  D +  R+    +
Sbjct: 64  GGPGAAYKYGLGWVLLAMIQLPAVWLSLGILGKKFAILARRYNAVTLNDMLFARYQS--R 121

Query: 123 WIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSV 182
            +  L S ++   F   +  Q++GG ++L T  G+  + G+LI  + I  YT  GG    
Sbjct: 122 LLVWLASLSLLVAFVGAMTVQFIGGARLLETAAGIPYETGLLIFGISIALYTAFGGFAPA 181

Query: 183 AYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTI---LGGMAG 239
           A     +A         A              + ++    LS A     TI   L    G
Sbjct: 182 AERHHARACDADWHRCAA-------------YWRSTCAGGLSNAVQTLQTIDPQLVTPQG 228

Query: 240 AAAIVFVIAEFSWF----FGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYI--G 293
           A  I+      S++    FG +G +   ++R ++ KD K   + R I IG  ++A +  G
Sbjct: 229 ADDILSPAFMTSFWVLVCFGVIG-LAHTAVRCISYKDSK--AVHRGIIIGTIVVAILMFG 285

Query: 294 ALMIGWIGIAIFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353
             + G +G A+     L  P+ V+P++M+K+ PP  A +F+   +AA++ST ++ L+ SS
Sbjct: 286 MHLAGALGRAVIPD--LHVPDLVIPTLMVKVLPPFAAGIFLAAPMAAIMSTINAQLLQSS 343

Query: 354 TEFSENI---LKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTW 410
               +++   ++P   +NE   ++   +S + T+ LG + L+ A+  P  +I+  +   +
Sbjct: 344 ATIIKDLYLNIRPDQMQNETRLKR---MSAVITLVLGALLLLAAWKPPEMIIWLNL-LAF 399

Query: 411 AGIGDTFSVIVILTLFWKRFHGK-AVPPTIIAGLLFTV 447
            G+   F   ++L L+W+R + K A+   I+ G+L+ V
Sbjct: 400 GGLEAVFLWPLVLGLYWERANAKGALSAMIVGGVLYAV 437


>pir||F83241 probable sodium:solute symporter PA3234 [imported] - Pseudomonas
           aeruginosa (strain PAO1)
           >gi|9949356|gb|AAG06622.1|AE004746_6 (AE004746) probable
           sodium:solute symporter [Pseudomonas aeruginosa]
           Length = 551
           
 Score =  117 bits (291), Expect = 2e-25
 Identities = 102/437 (23%), Positives = 201/437 (45%), Gaps = 31/437 (7%)

Query: 8   LAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGF 67
           + + V ++G  + +  +  ++ +S  D+  AG ++ G+   L+      SA   LG+   
Sbjct: 37  IVMFVAFVGATLCITYWASKRNRSAADYYAAGGRITGFQNGLAIAGDYMSAASFLGISAL 96

Query: 68  AFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRIL 127
            F +G   +  +IG ++G  +   + A RLR    KY   TF D  + R  +  K IR L
Sbjct: 97  VFTSGYDGLIYSIGFLVGWPIILFLIAERLRNLG-KY---TFADVASYRLKQ--KQIRTL 150

Query: 128 GSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTDT 187
            +        FY+ AQ +G GK++  LFGL+  + +++  ++++ Y + GG+ +  +   
Sbjct: 151 SACGSLVVVAFYLIAQMVGAGKLIELLFGLNYHVAVVLVGILMVLYVLFGGMLATTWVQI 210

Query: 188 VQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTIL--GGMAGAAAIVF 245
           ++A++    L+       I +  H     +++ +   K   K   I+  GG+       F
Sbjct: 211 IKAVL----LLSGASFMAIMVLKHVNFDVSTLFSEAIKVHPKGEAIMSPGGLVKDPISAF 266

Query: 246 VIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGWIGIAIF 305
            +  F+  FG   G+P + +RF  + D K A+ +     G+    YI   +IG+  I + 
Sbjct: 267 SLG-FALMFG-TAGLPHILMRFFTVSDAKEARKSVFYATGFIGYFYILTFIIGFGAILLV 324

Query: 306 GPN-GLKDPEQV------MPSVML------KLFPPALAAVFITGAVAAMLSTADSLLILS 352
             N   KD          M +V L       LF   ++AV    A A +L+    L +  
Sbjct: 325 STNPDFKDATGALIGGNNMAAVHLADAVGGSLFLGFISAV----AFATILAVVAGLTLAG 380

Query: 353 STEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAG 412
           ++  S ++        +A+ +  L VS++TTV+LG++A+++  +     I  +VG  ++ 
Sbjct: 381 ASAVSHDLYASVFKGGKANEKDELRVSKMTTVALGVVAIVLGILFEKQNIAFMVGLAFSI 440

Query: 413 IGDTFSVIVILTLFWKR 429
                  +++L+++WK+
Sbjct: 441 AASCNFPVLLLSMYWKK 457


>emb|CAB59438.1| (AL132644) putative transmembrane transport protein [Streptomyces
           coelicolor A3(2)]
           Length = 544
           
 Score =  117 bits (290), Expect = 3e-25
 Identities = 108/466 (23%), Positives = 205/466 (43%), Gaps = 32/466 (6%)

Query: 2   EARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCL 61
           E R  I+ +   ++   + + ++ GR+ K   DF   GRQ   +   L+      SA   
Sbjct: 19  EHRPLIITLFAVFVLATLGITVWAGRQTKDAADFYAGGRQFSAFQNGLAVSGDYMSAASF 78

Query: 62  LGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAE 121
           LG+ G     G      +IG ++  +VA  + A  LR    +Y     + Y  ++ P   
Sbjct: 79  LGIAGAIALFGYDGFLYSIGFLVAWLVALLLVAEPLRNSG-RYTMGDVLAYRMRQRP--- 134

Query: 122 KWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLG-MLITALV---ILPYTVMG 177
             +R     +      FY+ AQ  G G +++ L G+    G +LI ALV   ++ Y  +G
Sbjct: 135 --VRTAAGTSTIVVSIFYLLAQMAGAGILVSLLLGITSDAGKILIVALVGVLMIVYVTIG 192

Query: 178 GLKSVAYTDTVQAIVMIL-TLIVAPIVGVIYIANHPELYATSVT-----AALSKAGVKYS 231
           G+K   +   V+A+++I  T+++  +V + +  N  +L   +       +A  + G++Y 
Sbjct: 193 GMKGTTWVQMVKAVLLIGGTILITFLVLLKFDFNISDLLGKAAENSGAGSAFLEPGLQY- 251

Query: 232 TILGGMAGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAY 291
               G +G   + F+    +   G   G+P + IRF  + + K A+ + N  IG     Y
Sbjct: 252 ----GASGTTKLDFISLGIALVLG-TAGLPHILIRFYTVPNAKAARKSVNWAIGIIGAFY 306

Query: 292 IGALMIGWIGIAIFGPNGL--KDPEQVMPSVMLKL--------FPPALAAVFITGAVAAM 341
           +  + +G+   A+ G + +   +P     + +L L        +   L A     A A +
Sbjct: 307 LMTIALGFGAAALVGKDEIIASNPSGNTAAPLLALHVGGVDSTWGAILLATISAVAFATI 366

Query: 342 LSTADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHL 401
           L+    L + SS+ F+ +I    I K +A  ++ +  +R  TV +GI+++ +  +     
Sbjct: 367 LAVVAGLTLASSSSFAHDIYANVIRKGQATEKEEMRAARWATVFIGIVSIALGALARDLN 426

Query: 402 IYTIVGYTWAGIGDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTV 447
           +  +V   +A         ++ +LFWKRF  +    +I  GL+  V
Sbjct: 427 VAGLVALAFAVAASANLPTILYSLFWKRFTTQGALWSIYGGLIVAV 472


>sp|P32705|YJCG_ECOLI HYPOTHETICAL 59.2 KD PROTEIN IN SOXR-ACS INTERGENIC REGION (F549)
           >gi|7442761|pir||B65215 hypothetical 59.2 kD protein in
           soxR-acs intergenic region - Escherichia coli (strain
           K-12) >gi|396402|gb|AAC43161.1| (U00006) similar to
           Salmonella proline permease [Escherichia coli]
           >gi|1790503|gb|AAC77037.1| (AE000480) putative transport
           protein [Escherichia coli K12]
           Length = 549
           
 Score =  111 bits (274), Expect = 2e-23
 Identities = 103/450 (22%), Positives = 200/450 (43%), Gaps = 54/450 (12%)

Query: 6   QILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLP 65
           Q + + + ++ F + +  +  ++ +S  D+  AG  + G+   L+      SA   LG+ 
Sbjct: 34  QAIIMFLIFVVFTLGITYWASKRVRSRSDYYTAGGNITGFQNGLAIAGDYMSAASFLGIS 93

Query: 66  GFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIR 125
              F +G   +  ++G ++G  +   + A RLR    +Y       Y  K+ P     IR
Sbjct: 94  ALVFTSGYDGLIYSLGFLVGWPIILFLIAERLRNLG-RYTFADVASYRLKQGP-----IR 147

Query: 126 ILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYT 185
           IL +         Y+ AQ +G GK++  LFGL+  + +++  ++++ Y + GG+ +  + 
Sbjct: 148 ILSACGSLVVVALYLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWV 207

Query: 186 DTVQAIVMI-----LTLIVAPIVGVIY-------IANHPELYATSVTAALSKAGVKYSTI 233
             ++A++++     +  +V   VG  +       +A HP+         L K  +   ++
Sbjct: 208 QIIKAVLLLFGASFMAFMVMKHVGFSFNNLFSEAMAVHPKGVDIMKPGGLVKDPISALSL 267

Query: 234 -LGGMAGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYI 292
            LG M G A                 G+P + +RF  + D + A+ +     G+    YI
Sbjct: 268 GLGLMFGTA-----------------GLPHILMRFFTVSDAREARKSVFYATGFMGYFYI 310

Query: 293 GALMIGWIGIAIFGPN-GLKDPE------QVMPSVML------KLFPPALAAVFITGAVA 339
              +IG+  I + G N   KD          M +V L       LF   ++AV    A A
Sbjct: 311 LTFIIGFGAIMLVGANPEYKDAAGHLIGGNNMAAVHLANAVGGNLFLGFISAV----AFA 366

Query: 340 AMLSTADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPS 399
            +L+    L +  ++  S + L   ++K  A  R+ L VS++T + LG+IA+I+  +  +
Sbjct: 367 TILAVVAGLTLAGASAVSHD-LYANVFKKGATEREELRVSKITVLILGVIAIILGVLFEN 425

Query: 400 HLIYTIVGYTWAGIGDTFSVIVILTLFWKR 429
             I  +VG  +A        I++L+++W +
Sbjct: 426 QNIAFMVGLAFAIAASCNFPIILLSMYWSK 455


>dbj|BAB07462.1| (AP001519) Na+/solute symporter (Ssf family) [Bacillus halodurans]
           Length = 554
           
 Score =  109 bits (271), Expect = 5e-23
 Identities = 109/486 (22%), Positives = 206/486 (41%), Gaps = 51/486 (10%)

Query: 7   ILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPG 66
           I+++L+    F + +GI    +A++  DF +A R +P +   ++      SA   +G+ G
Sbjct: 6   IVSILMILATFGLYIGISIYNRARATSDFYVASRGVPPFWNGMAIGGDWMSAASFIGMAG 65

Query: 67  FAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRI 126
                G   +   +G   G +    +FA +LRK    Y   T  ++I  R+       R+
Sbjct: 66  TIMILGYDGLAYIMGWTGGYLFLTFLFAPQLRK----YGRYTVPEFIGDRY--GSNTARL 119

Query: 127 LGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTD 186
           + +       F Y+  Q  G G V+  +  +    G +I  +VI  Y  +GG+K + +T 
Sbjct: 120 IAAIATIIISFTYIIGQLSGSGVVIGRILNIPAMYGTMIGVVVIAIYATLGGMKGITWTQ 179

Query: 187 TVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVK----YSTILGGMAGAAA 242
             Q I++I+  I+  +   + ++ +P  + T         G+      S IL     +  
Sbjct: 180 VAQYIILIVAYIIPIVFMSLQLSGNPFPWLTYGNFISQLDGLDQELGLSQILQPFMESDK 239

Query: 243 IVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGA-------- 294
             F+   F+   G    +P + +RF  +   K A+ +    + +  + Y+ A        
Sbjct: 240 SQFIALMFTLMVG-TAALPHVIVRFYTVTTMKAARWSGAWALIFIALLYLSAPAYAAFSR 298

Query: 295 --LMI---------------GWIGIAIF------GPNGLKDPEQVMPSVMLKLFPPALA- 330
             LM                 WI   +       G   L+  E  + + ++ +  P +A 
Sbjct: 299 FILMTQVANQPIDQLPAWTEAWINTGLLEMADANGDGILQWEELRISNDIVVMATPEIAN 358

Query: 331 ------AVFITGAVAAMLSTADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTV 384
                  +   GA+AA LSTA  LLI  S+ F+ +I    +   +A  +K L+  R+  V
Sbjct: 359 LGMFVIGLVAAGAMAAALSTAGGLLITISSSFAHDIYY-RLMNPKASDQKRLLAGRIAIV 417

Query: 385 SLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVIVILTLFWKRFHGKAVPPTIIAGLL 444
              I+A ++A + P  +I  IV + +   G  F  +++L ++WKR + K     +++GL 
Sbjct: 418 LATIVAGVVA-LDPPGVITQIVAWAFGLAGGAFFPVLLLGVWWKRANAKGAIAGMLSGLA 476

Query: 445 FTVFWI 450
            T+ +I
Sbjct: 477 VTLVYI 482


>gi|11498574 proline permease (putP-2) [Archaeoglobus fulgidus]
           >gi|7442764|pir||A69371 proline permease (putP-2)
           homolog - Archaeoglobus fulgidus
           >gi|2649629|gb|AAB90273.1| (AE001037) proline permease
           (putP-2) [Archaeoglobus fulgidus]
           Length = 531
           
 Score =  105 bits (260), Expect = 1e-21
 Identities = 116/491 (23%), Positives = 215/491 (43%), Gaps = 63/491 (12%)

Query: 2   EARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCL 61
           +    ++ + V Y   +I +G Y  ++ KS  D+ +AGRQ+   V  L+  +T  S   +
Sbjct: 3   QVEAPVIGITVLYFLAIIIIGYYSRQRLKSATDYYVAGRQVGAVVNGLALESTYLSPASM 62

Query: 62  LGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAE 121
           LGLP + F  G    W     + G+ +A  + A  LR    KY   +F DY A R+ +  
Sbjct: 63  LGLPAYIFILGYPFWWAMSAIIAGMPIATLLTASALR----KYAPTSFADYYADRYNDQR 118

Query: 122 -KWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLK 180
            +W  ++G  T+      Y+    +G    L  +  +   +G+++  ++++ Y V GG+ 
Sbjct: 119 LRW--LVGIVTV-IGAVLYITLSLVGMALFLLAVAKVPYIIGLIVGTIIVMLYVVWGGMI 175

Query: 181 SVAYTDTVQAIVMILTLIVAPIVGVI-----------YIANHPELYATSVTAALSKAGVK 229
           + ++    QA +M +  ++A  V VI            +AN+P+ + T        +  +
Sbjct: 176 ATSWNAAFQAFLMTVAAVIAAAVIVIKLGGLGGFYEAVLANNPKFWNT-------PSDPE 228

Query: 230 YSTILGGMAGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNI------- 282
              +L G   A    F    F W +G+   MP   +RF    D K A+  R+I       
Sbjct: 229 PPHLLSGTWIAVIGWF----FVWHYGF-ATMPYTVVRFFTTMDIKTAR--RSIFWCTLAA 281

Query: 283 GIGWTIIAYIGA---LMI--GWIG-------------IAIFGPNGLKDPEQVMPSVMLKL 324
           GI +  +  IGA   LMI  G +G             +A +G  G  D   +  + +  L
Sbjct: 282 GIFYMALEIIGAASKLMIETGPMGGEGANAVKILQSYMAQYGVGGWTDYSMI--AAVEAL 339

Query: 325 FPPALAAVFITGAVAAMLSTADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTV 384
             P +  +   G +A  +STA   +++ +T  + +     + K++    K + ++R+ +V
Sbjct: 340 QNPWVLGILCAGGLAIAMSTAAGWVMVVNTLLTRD-WGDMLLKSKFAKEKPVTLARIISV 398

Query: 385 SLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVIVILTLFWKRFHGKAVPPT-IIAGL 443
              I+  ++A + P  L+  + G+ +  I       ++L L+WKR    A+  T I+   
Sbjct: 399 IFLIVGFLVA-INPPGLVLDLSGWAFVVIISALGPGLVLGLWWKRATRAAMWTTAIVMTP 457

Query: 444 LFTVFWISSGL 454
           L    W+ + L
Sbjct: 458 LHLYAWLKAKL 468


>pir||C82582 Na+-dependent symport homolog XF2251 [imported] - Xylella
           fastidiosa (strain 9a5c)
           >gi|9107405|gb|AAF85050.1|AE004037_11 (AE004037)
           solute:Na+ symporter [Xylella fastidiosa]
           Length = 577
           
 Score =  104 bits (257), Expect = 2e-21
 Identities = 101/447 (22%), Positives = 200/447 (44%), Gaps = 32/447 (7%)

Query: 7   ILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPG 66
           ++++ V ++   + +  +  ++ +S  DF  AG  + G+   L+      SA   LG+  
Sbjct: 38  VISIFVVFVLITLWITKWAAKRTRSSADFYTAGGTITGFQNGLAMAGDYMSAAAFLGITS 97

Query: 67  FAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRI 126
               +G   +  AIG ++G  +   + A RLR    KY   TF D +A R       +R+
Sbjct: 98  AVMISGYDGMLYAIGSLVGWPILVFLVAERLRNLG-KY---TFADVVAYRFAAVP--VRL 151

Query: 127 LGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTD 186
             SA+        + AQ +G G ++  LFGLD  + +++   +++ Y + GG+ +  +  
Sbjct: 152 FTSASTLVVVLCSLVAQMVGAGALIKLLFGLDYWVAVILVGGLMMVYVMFGGMAATTWVQ 211

Query: 187 TVQAIVMILTL-IVAPIVGVIYIANHPELYA------TSVTAALSKAGVKYSTI-LGGMA 238
            ++A++++  L  +A ++   +  N   L+A      T +  A  K+G +   + L  MA
Sbjct: 212 IIKAVLLLTCLTFMAVMIMWRFGFNFEGLFASAVGVKTQIAMAGGKSGEEAKALGLSIMA 271

Query: 239 GAAAIVFVIAEFSW----FFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGA 294
             + I   I+  S      FG +G +P + +RF A+ D +  + +    I W    YI  
Sbjct: 272 PGSFIKDPISAISLGIALVFGNVG-LPHILMRFFAVPDAREVRHSVLWAITWIGYCYILM 330

Query: 295 LMIGWIGIAIFGPN------------GLKDPEQVMPSVMLKLFPPALAAVFITG-AVAAM 341
            ++G+  I     N            G +    +   ++ K+    +   F++  A A +
Sbjct: 331 FIVGFGAIVFVLTNPQYADIATGTIRGGQGAANMAAVLVAKVVGGDVFMGFVSAVAFATI 390

Query: 342 LSTADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHL 401
           L+ A  L +  ++  S ++    I + +      L+VSR+TT  LG++A+++  V     
Sbjct: 391 LAVAAGLALSGASAVSHDVYAMVIKQGKPSSDTELLVSRVTTAVLGVVAVLLGIVFQKQN 450

Query: 402 IYTIVGYTWAGIGDTFSVIVILTLFWK 428
           +  +V   +A        ++IL+L WK
Sbjct: 451 VAFMVSLAFAIAASANFPVLILSLLWK 477


>pir||H75513 probable sodium/proline symporter DR0477 [similarity] - Deinococcus
           radiodurans (strain R1)
           >gi|6458165|gb|AAF10057.1|AE001907_3 (AE001907)
           sodium:solute symporter protein [Deinococcus
           radiodurans]
           Length = 528
           
 Score =  102 bits (252), Expect = 9e-21
 Identities = 96/464 (20%), Positives = 203/464 (43%), Gaps = 35/464 (7%)

Query: 5   TQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGL 64
           T +LA L+  +   + V  +   +  S  DF +AG ++      ++      SA   LG+
Sbjct: 2   TFLLAALIVLI--TLGVTFWASSRNTSAGDFYVAGGKISATQNGIAIAGDYMSAASFLGI 59

Query: 65  PGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWI 124
            G     G      ++G  +  +    + A  LR    KY     + Y  K     ++ +
Sbjct: 60  TGLIALNGYDGFMYSVGWFIAYLTVLFIVAEPLRNLG-KYTLADMLVYRLK-----DQRV 113

Query: 125 RILGSATIAFFFFFYVGAQYLGGGKVLNTLFG--LDPKLGMLITALVILPYTVMGGLKSV 182
           R   + +      FY+ AQ +G G +++ L G  L P L + +  L+++ Y V+GG+ + 
Sbjct: 114 RFYAAFSTITVSTFYMIAQVVGAGSLISLLSGGLLKPTLAIPLVGLLMIVYVVVGGMLAT 173

Query: 183 AYTDTVQA-IVMILTLIVAPIVGVIYIANHPELYATSVT---AALSKAGVKYSTILGGMA 238
            +   ++A ++M  T++++ ++   +  +  +L   +     AA  + G+KY   L  ++
Sbjct: 174 TWVQIIKAMLLMFATIVMSVLILARFGFSFSDLLGAATDKNGAAFLEPGLKYKNPLDLIS 233

Query: 239 GAAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIG 298
              A+V   A          G+P + +RF  +   ++A+ +  + +G     YI   ++G
Sbjct: 234 LCLALVLGTA----------GLPHILVRFFTVPTAQDARKSVVVAMGLIGAFYIMTALMG 283

Query: 299 WIGIAIFGPNGL--KDPEQVMPSVMLK--------LFPPALAAVFITG-AVAAMLSTADS 347
                + G + +   +P   M + +L                  F+T  A A +L+    
Sbjct: 284 NAANVLVGKDTIVAANPAGNMAAPLLAQALGGGAGTLGGEFGLAFVTAVAFATILAVVAG 343

Query: 348 LLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVG 407
           L I +ST F+ +I    +   +A+ ++   V+R+ TV++G++++++  +     +  +V 
Sbjct: 344 LTISASTSFTHDIYNGVMKGGKANEQEQFKVARMATVAVGLLSIVLGLLAKDQNVAFLVA 403

Query: 408 YTWAGIGDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWIS 451
             +A        +++ TLFW+ F+       I+ GL  T+  I+
Sbjct: 404 LAFAIAASANLPVILYTLFWRGFNANGAVWGIVGGLAVTLVLIA 447


>gi|11497853 pantothenate permease (panF-3) [Archaeoglobus fulgidus]
           >gi|7442769|pir||E69279 pantothenate permease (panF-3)
           homolog - Archaeoglobus fulgidus
           >gi|2650404|gb|AAB90996.1| (AE001089) pantothenate
           permease (panF-3) [Archaeoglobus fulgidus]
           Length = 461
           
 Score =  102 bits (251), Expect = 1e-20
 Identities = 96/407 (23%), Positives = 201/407 (48%), Gaps = 37/407 (9%)

Query: 6   QILAVLVFYLGFLI---SVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLL 62
           +++  L  ++G++I   ++ I   +  ++ +++ IAGR++ G ++AL+  AT  SA+ ++
Sbjct: 3   KLIEFLYAFIGYIIIGTAIAIMAMKGLRTQEEYYIAGRKVSGVISALTYAATTYSAFMMV 62

Query: 63  GLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRH-PEAE 121
           GL G ++ +G+ A+   +  ++G +   + +A R+ + A++   VT  D IA+R+  E  
Sbjct: 63  GLVGLSYFSGVGALGFELFYLVGTLFLLSYYAPRVWEMAKERGYVTPGDMIAERYGSEVA 122

Query: 122 KWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKS 181
           K + ++    ++     Y+  Q +G   +L+    +  + G++ +A++I  +  +GGL+ 
Sbjct: 123 KLMAVI----VSIALIPYISVQLIGVSLILSKTNAMSFEAGIVASAILIALWAFLGGLRG 178

Query: 182 VAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAA 241
           VA+TD +Q + M+L + +A I+ V       + + T V + L +  V  ++I        
Sbjct: 179 VAWTDALQGVFMLL-MAIAAILWVHQYGFAEKDFFTEV-SRLGELLVVPNSIW------T 230

Query: 242 AIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGW------TIIAYIGAL 295
            + F+     WFF  L   PQ+  R + I  D++A     I  G+       I+  IG  
Sbjct: 231 PVKFISLTLPWFFFALTN-PQVFQR-LYIPKDRSALRRMVILFGFFGLIYTVIVTLIGLE 288

Query: 296 MIGWIGIAIFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTE 355
           +     + +F    + D + V P+ ML + PP L A       AA ++TA+S+++  S+ 
Sbjct: 289 LRTMTEMGVFPK--VPDRDAVTPT-MLAMMPPLLGAAISLSIFAAAITTANSIVLTLSSM 345

Query: 356 FSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLI 402
            + ++L            + +   R+  V L +   + AY  P +++
Sbjct: 346 ITRDLL----------GSEKVGSGRVLIVILTVAVALFAYSRPGYIV 382


>gi|11497636 proline permease (putP-1) [Archaeoglobus fulgidus]
           >gi|7442766|pir||G69251 proline permease (putP-1)
           homolog - Archaeoglobus fulgidus
           >gi|2650635|gb|AAB91210.1| (AE001105) proline permease
           (putP-1) [Archaeoglobus fulgidus]
           Length = 491
           
 Score =  101 bits (250), Expect = 2e-20
 Identities = 103/481 (21%), Positives = 196/481 (40%), Gaps = 27/481 (5%)

Query: 3   ARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLL 62
           A T  +++++ Y    +++G +  RK K+ + +  A +    +V A++  +   SA+  +
Sbjct: 2   ADTITVSIVLAYFVVTLALGFFAARKIKTAEHYYGARKLFGMFVTAVAVFSGIASAFTFI 61

Query: 63  GLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEK 122
           G PG  +  G    W     V+ + + W +   R++   E     T  D  A R      
Sbjct: 62  GGPGLVYPMGGTVNWVIWTPVISMPLIWYLLGKRIKLITEARPVATLPDLTAARFKSDA- 120

Query: 123 WIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSV 182
            +R L +  + F    Y+    +G G VL  + G   +L + I   +I+ YT  GG+ + 
Sbjct: 121 -VRFLTAVALIFGIITYLAGNVMGAGLVLTDMLGTPLELSIAIVFGIIMLYTAFGGMVAS 179

Query: 183 AYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAA 242
             TD  Q +VM++  I+  +  +I       L+AT     ++++  ++   +    G   
Sbjct: 180 ILTDFFQGLVMMVAAIIFVVFILIMTGGVENLFAT-----IAESNPRHIDPI----GVGP 230

Query: 243 IVFVIAEFSWFFGYLGGM-PQLSIRFMAIKDDKNAKLARNI-GIGWTIIA---YIGALMI 297
           I   I  + W       + P    +F A+KD ++ K    +  I WT+     + G    
Sbjct: 231 IWLGIMGWWWALNIGSSVQPHAVTKFFALKDYRDLKWGALVTTIAWTLACLMWFFGGYAS 290

Query: 298 GWIGIAIFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFS 357
            W+ I        +  + +    ++   P  L AV   G +AA++ST    + + +    
Sbjct: 291 VWVVIKGLAEAPARSDQAIFG--VIAQMPVVLKAVIYAGVLAAIMSTVSGFISMGTAAVV 348

Query: 358 ENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTF 417
            +I  P         R  ++  R+ TV L ++A +  Y    +++  +V           
Sbjct: 349 RDI--PTAIGKSLSQRGQILWGRVVTVILTVVAALFGY-YGGYVVGILVTLGLGYFASML 405

Query: 418 SVIVILTLFWKRFHGKA----VPPTIIAGLLFTVFWISSGLDAKVSVRLMNFIVTFIVAI 473
             ++++ L WKR   +A       T+   L F V+     L   +   L  + VTF V I
Sbjct: 406 FPLLVIGLNWKRATKEAAIITTALTVAMNLGFLVY--EKVLSMSLPYGLPGYGVTFAVGI 463

Query: 474 I 474
           I
Sbjct: 464 I 464


>pir||G83610 probable sodium:solute symporter PA0287 [imported] - Pseudomonas
           aeruginosa (strain PAO1)
           >gi|9946130|gb|AAG03676.1|AE004466_10 (AE004466)
           probable sodium:solute symporter [Pseudomonas
           aeruginosa]
           Length = 461
           
 Score =  101 bits (249), Expect = 2e-20
 Identities = 107/478 (22%), Positives = 208/478 (43%), Gaps = 45/478 (9%)

Query: 10  VLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQL-PG-WVAALSERATGESAWCLLGLPGF 67
           +++ Y   ++ +G Y  RKAKS  DF +AGR+L PG ++  ++    G ++   +G    
Sbjct: 7   IMLVYALAMLGLGWYGMRKAKSQSDFLVAGRRLGPGLYLGTMAAVVLGGAS--TIGTVKL 64

Query: 68  AFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRIL 127
            +  GL+ +W      LGIIV   VF+    ++  +    T    + +R+  +    R++
Sbjct: 65  GYQFGLSGLWLVFMLGLGIIVLSLVFS----RQIARLRVFTVTQVLEQRYQASS---RLI 117

Query: 128 GSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTDT 187
           G   +  +         +  G V   +FG+     +L    +++ Y+V+GG+ S+  TD 
Sbjct: 118 GGVVMVAYDLMVAVTATIAIGSVTEVVFGIPRIPAILCGGGIVIVYSVIGGMWSLTLTDI 177

Query: 188 VQAIV----MILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAAI 243
           +Q ++    + L L+   I G   +A   E+             +   TIL         
Sbjct: 178 IQFVIKTVGIFLVLLPLSIDGAGGLARMQEVLPAGF---FDLGHIGLDTIL--------T 226

Query: 244 VFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGWIGIA 303
            F++    +FFG L G       F A    ++  + R  G+G  +   +       IG A
Sbjct: 227 YFLL----YFFGALIGQDIWQRVFTA----RSETVVRYAGLGAGVYCMLYGAACALIGAA 278

Query: 304 --IFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSENIL 361
             +  P+ L  PE     +  ++  P L  + +  A++A++STA   L+ ++T   E+I 
Sbjct: 279 ARVLLPD-LAVPENAYAEITREVLAPGLRGLVVAAALSAIMSTASGCLLAAATVLQEDIY 337

Query: 362 KPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVIV 421
             ++          + +SR  T+ +G+  L++A +V   +    + Y     G    V +
Sbjct: 338 ARFL---RPGTTSDIRLSRCITLLMGVAMLVLACLVNDVIAALSIAYNLLVGG--LLVPI 392

Query: 422 ILTLFWKRFHGKAVPPTIIAGLLFTVFWIS-SGL--DAKVSVRLMNFIVTFIVAIIAT 476
           +  L W+R   +    +I+AG L  +  ++  GL  ++ +   L+  + TF+   +AT
Sbjct: 393 VGALLWRRASPQGAIASIVAGCLAVIACMARDGLLANSPIVYGLLASLATFVAVSLAT 450


>emb|CAA94864.1| (Z71176) phenylacetic acid permease [Pseudomonas putida]
           >gi|3253206|gb|AAC24338.1| (AF029714) PhaJ [Pseudomonas
           putida]
           Length = 520
           
 Score =  101 bits (248), Expect = 3e-20
 Identities = 102/468 (21%), Positives = 206/468 (43%), Gaps = 31/468 (6%)

Query: 8   LAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGF 67
           +++ + ++ F + V  +   + +S  DF  AG  L G    L+      SA   LG+   
Sbjct: 6   ISMFMVFVCFTLLVTRWAALRTRSASDFYTAGGGLTGMQNGLAIAGDMISAASFLGISAM 65

Query: 68  AFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRIL 127
            F  G   +  A+G + G  +   + A RLR    KY   TF D ++ R   A+  +R+ 
Sbjct: 66  MFMNGYDGLLYALGVLAGWPIILFLIAERLRNLG-KY---TFADVVSYRL--AQTPVRLT 119

Query: 128 GSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTDT 187
            +         Y+ AQ +G GK++  LFG+     +++  ++++ Y   GG+ +  +   
Sbjct: 120 SAFGTLVVALMYLVAQMVGAGKLIELLFGISYLYAVMLVGVLMVAYVTFGGMLATTWVQI 179

Query: 188 VQAIVMIL-TLIVAPIVGVIYIANHPELYATSVTA-ALSKAGVKYSTILGGMAGAAAIVF 245
           ++A++++  T  +A +V   +  +   ++A++V   A  +A +    +L     A ++  
Sbjct: 180 IKAVMLLSGTSFMAFMVLKHFGFSTEAMFASAVAVHAKGQAIMAPGGLLSNPVDAISL-- 237

Query: 246 VIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGWIGIAIF 305
                   FG   G+P + +RF  + D K A+ +     G+    Y+  ++IG+  I + 
Sbjct: 238 ---GLGMMFG-TAGLPHILMRFFTVSDAKEARKSVFYATGFIGYFYLLLIVIGFGAIVMV 293

Query: 306 GPN-------------GLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILS 352
           G               G      +  +V   LF   ++AV    A A +L+    L +  
Sbjct: 294 GTEPSYRDATGAIIGGGNMIAVHLAQAVGGNLFLGFISAV----AFATILAVVAGLALSG 349

Query: 353 STEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAG 412
           ++  S ++    I + +A  ++ + VSR+ T+ +G++A+++  +  S  I  + G   A 
Sbjct: 350 ASAVSHDLYACVIRQGKATEQEEMRVSRIATLLIGLLAVLLGLMFESQNIAFLSGLVLAV 409

Query: 413 IGDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSGLDAKVSV 460
                  +++L++FWK    +      +AGL   V  +  G    V+V
Sbjct: 410 AASVNFPVLLLSMFWKGLTTRGAVCGSMAGLASAVLLVVLGPAVWVNV 457


>pir||E83468 probable sodium:solute symport protein PA1418 [imported] -
           Pseudomonas aeruginosa (strain PAO1)
           >gi|9947366|gb|AAG04807.1|AE004571_6 (AE004571) probable
           sodium:solute symport protein [Pseudomonas aeruginosa]
           Length = 463
           
 Score =  101 bits (248), Expect = 3e-20
 Identities = 121/471 (25%), Positives = 209/471 (43%), Gaps = 42/471 (8%)

Query: 10  VLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQL-PGWVAALSERATGESAWCLLGLPGFA 68
           V++ Y   +I++G Y  R+AK+  D+ +AGR L PG+    +  AT       +G     
Sbjct: 7   VVLIYAAGMIALGWYGMRRAKTRDDYLVAGRNLGPGFYLG-TMAATVLGGASTIGTVRLG 65

Query: 69  FAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRILG 128
           +  G++  W      LGI V  ++F   L K   K    T    + +R+  A +      
Sbjct: 66  YVHGISGFWLCGAIGLGI-VGLSLF---LAKPLLKLKIYTVTQVLERRYNPAARH----A 117

Query: 129 SATIAFFFFFYVGA-QYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTDT 187
           SA I   +   +GA   +  G V+  LFGL   + +LI   V++ Y+ +GG+ S+  TD 
Sbjct: 118 SALIMLVYALMIGATSTIAIGTVMQVLFGLPFWVSILIGGGVVVLYSTIGGMWSLTLTDI 177

Query: 188 VQAIVMILTLIVAPIVGVIYIANHPELY-ATSVTAALSKAGVKYSTILGGMAGAAAIVFV 246
           VQ ++M         VG++++     +  A    A ++K    Y              F+
Sbjct: 178 VQFLIM--------TVGLVFLLMPLSINDAGGWDALVAKLPASYFDFTAIGWDTIVTYFL 229

Query: 247 IAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARN-IGIGWTIIAYIGALMIGWIGIA-- 303
           I    +FFG   G   +  R    + +  AK+A +  GI   +    GAL    IG+A  
Sbjct: 230 I----YFFGIFIGQ-DIWQRVFTARSETVAKVAGSAAGIYCVLYGMAGAL----IGMAAK 280

Query: 304 IFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSENILKP 363
           +  P+ L++      SV+    P  +  + I  A+AA++STA + L+ +ST  ++++L  
Sbjct: 281 VLLPD-LENVNNAFASVVEHSLPNGIRGLVIAAALAALMSTASAGLLAASTTVTQDLLPR 339

Query: 364 YIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVIVIL 423
                       +  +R+ T+ LG++ L +A VV   +    V Y     G    + +I 
Sbjct: 340 LRRGRGQSDNGDVHENRIATLLLGLVVLGIALVVSDVISALTVAYNLLVGG--MLIPLIG 397

Query: 424 TLFWKR-FHGKAVPPTIIAGLLFTVFWISSGLDA------KVSVRLMNFIV 467
            ++WKR     A+    +  L   VF I  GLDA       ++V L++F++
Sbjct: 398 AIYWKRATTAGAITSMTLGFLTVLVFMIKDGLDANTPIYYSLAVGLLSFVL 448


>pir||S75887 hypothetical protein - Synechocystis sp. (strain PCC 6803)
           >gi|1653432|dbj|BAA18346.1| (D90913) sodium-coupled
           permease [Synechocystis sp.]
           Length = 512
           
 Score =  100 bits (247), Expect = 3e-20
 Identities = 103/448 (22%), Positives = 191/448 (41%), Gaps = 63/448 (14%)

Query: 9   AVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGFA 68
           A+++ Y   +I++G    RK  +  ++    +Q+P W    S  AT  SA  LLG PG  
Sbjct: 7   AIVLVYSAIVIAIGAIASRKQDNTDEYFRGAKQIPWWALGFSIIATSFSAASLLGGPGEG 66

Query: 69  FAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRILG 128
           +  G   +   +G ++G  +  AVF         + +  T  +Y+ +R    +   R LG
Sbjct: 67  YGHGFLYLQLQLGDLIGYGLVIAVFLPFF----VRLNLTTAYEYLERRF---DAKTRSLG 119

Query: 129 SATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTDTV 188
           S     F    +G        VL+ L G+     +L+  +V + YTV GG+ +V +TD +
Sbjct: 120 SLCFLLFVIARLGGLLYAAALVLSVLTGISTNTAILMVGVVSIIYTVAGGITAVVWTDVL 179

Query: 189 QAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAAIVFVIA 248
           Q              G+I++     ++A +VTA     G  +   + G  G      V+ 
Sbjct: 180 Q-------------FGMIFVGLGAGIWA-AVTAVPGGFGELWR--IAGENGK----LVVF 219

Query: 249 EFSW------------------FFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGW-TII 289
            F W                   F   G   Q   R+++  D+++A+ A  I +GW + +
Sbjct: 220 NFDWDPASIRSLPTALIAYGILAFAVAGTNQQSVQRYVSCADEQSARKA--IFLGWFSGV 277

Query: 290 AYIGALMIGWIGIAIFG--------PNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAM 341
             +GA ++  +G+ +F         P  +K P++++   ++   PP  +   +    AA 
Sbjct: 278 LGVGATLL--LGVLLFSFYQLQGGLPGNIK-PDEILSYFIVNQVPPGASGFLVAAIFAAA 334

Query: 342 LSTADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPS-- 399
           +S+ DS L   +T  + +    YI   +A   +S+ V++   +  G++A+  A    S  
Sbjct: 335 MSSIDSALHSLATCMTVDFYDRYI-NIQASEMRSVRVAQGLIIVWGVVAIFSAIYAASTG 393

Query: 400 -HLIYTIVGYTWAGIGDTFSVIVILTLF 426
             L+  +V YT   +G    + ++  LF
Sbjct: 394 QDLLEFLVSYTTMFLGPLLGIFLMGVLF 421


>pir||H71097 hypothetical protein PH1044 - Pyrococcus horikoshii
           >gi|3257459|dbj|BAA30142.1| (AP000004) 491aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 491
           
 Score = 99.1 bits (243), Expect = 1e-19
 Identities = 120/487 (24%), Positives = 224/487 (45%), Gaps = 34/487 (6%)

Query: 9   AVLVFYLGFL---ISVGIYQGRKAK-SHKDFSIAGRQLPGWVAALSERATGE--SAWCLL 62
           + L+  LG++   + VG+  G K K + + + ++GR L   +  L     GE  SA+  L
Sbjct: 15  SALIIVLGWVFLSLIVGVMAGIKRKFTLEGYLVSGRTLG--LIFLYVLMAGEIYSAYAFL 72

Query: 63  GLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEK 122
           G  G+A++ G+  ++ AIG           +A  + K  + +  VT  DY   R+    K
Sbjct: 73  GTGGWAYSYGMPIMY-AIGYGALAYSFGYFYARYVWKAGKAFGCVTQADYFQVRYNS--K 129

Query: 123 WIRILGSATIAFFFFFYVGAQYLGGGKVLN--TLFGLDPKLGMLITALVILPYTVMGGLK 180
            + +L +     F   Y+  Q  G G +++  +L  + PK G++I  ++++ Y    GL+
Sbjct: 130 ALAVLVALIGIIFNIPYLQLQLQGLGYIVHVGSLGSITPKAGIVIGMIIMMIYVYTSGLR 189

Query: 181 SVAYTDTVQAIVM-ILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239
            +++T+ +QA +M I+  +V   +         EL+ T     L++    +  +   +  
Sbjct: 190 GISWTNLLQATLMFIVAWVVLFTIPFKQFGGIGELFKT-----LAQTKPDHLILHPPLGI 244

Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299
           +  +  +I     FF Y    PQL       +D K  K  RN  +      ++  +++  
Sbjct: 245 SWYVSTLILSGLGFFMY----PQLYPSIYGARDLKTLK--RNYVLLPLYSIFMIPVILAG 298

Query: 300 IGIAIFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSEN 359
             +A  G   L  P++ +   +   +P  +  V      AA  STA ++L+  +   S+N
Sbjct: 299 FTVAALGIK-LSAPDEAVLKAVEITYPSWVLGVVGAAGFAAAASTASAILLSLAGLLSKN 357

Query: 360 ILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSV 419
           +    I K  A  ++ ++VSR++ + LG++A+ +A   P  L+ +++   +AG+   F  
Sbjct: 358 LYA--IAKPTASDKELVLVSRISVILLGLLAMGLALYSPGRLV-SLLLLAYAGMTQMFPG 414

Query: 420 IVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSGLDAK---VSVRLMNFIVTFIVAIIAT 476
             +  LFWKR +  A    IIAGL+ TV ++   L      +   L   +V  IV +I  
Sbjct: 415 -AVFGLFWKRMNKYATGTGIIAGLI-TVAYLRLVLKKNPLGIHFGLWGLLVNIIVTLIVA 472

Query: 477 YAIKPEK 483
           Y  KPE+
Sbjct: 473 YLTKPEE 479


>gi|11498821 proline permease (putP-3) [Archaeoglobus fulgidus]
           >gi|7483927|pir||E69402 proline permease (putP-3)
           homolog - Archaeoglobus fulgidus
           >gi|2649354|gb|AAB90016.1| (AE001019) proline permease
           (putP-3) [Archaeoglobus fulgidus]
           Length = 479
           
 Score = 98.3 bits (241), Expect = 2e-19
 Identities = 116/483 (24%), Positives = 206/483 (42%), Gaps = 57/483 (11%)

Query: 34  DFSIAGRQLPGWVAALSERATGESAWCLLGLPGFAFAAGLAAIWPAI-GCVLGIIVAWAV 92
           DF  A  QL  W   L    +  S   L+G+ G AF  G A +W  I G    I     +
Sbjct: 3   DFVAASGQLGFWTYCLLMIGSVFSGMTLIGVAGLAFTTGYANVWERIIGPPFAIAFGTIL 62

Query: 93  FAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRILGSATIAFFFFFYVGAQYLGGGKVLN 152
              +L    +K   +T  DY+A R+ +  K IRIL     A   F Y+  QY   G V  
Sbjct: 63  IGYKLFNLKDKNGILTIQDYLAFRYDDP-KIIRILAGLISAVTCFVYLIGQYTAIGVVSY 121

Query: 153 TLFGLDPKLGMLITALVILPYTVMGGLKSVAYTDTVQAIVMILTLIVAPIVGVIYI---- 208
            + G+   LG +I A++++ Y + GG+ S A+T  +Q+I+M+L + V     + ++    
Sbjct: 122 VVLGIPYWLGAVIAAVIVVAYVMSGGMFSTAWTTFLQSILMLLGIYVTVPFIIAWVGGFE 181

Query: 209 ------ANHPELYATS-----------------VTAALSKAGVKYSTILGGMA---GAAA 242
                 A  PE+   +                   A++  AG  Y+  L G+    G   
Sbjct: 182 AMNQALAAMPEIQNATRGVAENFMFAKYLSKPFAPASVPLAGWVYNLTLFGITVPLGLMV 241

Query: 243 IVFVIAEFSWF----FGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIG 298
              ++     F    +   G +    I F AI     A +A  +     +I  I +L +G
Sbjct: 242 APHIVNNMLTFRKIEYTRWGPLVMYVIGFSAIFLTALAGMAARVAWAKGMID-IPSLTLG 300

Query: 299 WIGIAIFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSE 358
            I +        K  +   P++  K  P  L  + +   +A ++ST D L++ ++   S 
Sbjct: 301 SIEV--------KWSDMAYPTIASKALPYWLFVLLLPTILAGVMSTTDRLILTAANNISY 352

Query: 359 NILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFS 418
           ++L+  + KN ++      V+ L    +G  +L++A + P  L+   +    + + + F 
Sbjct: 353 DVLRNALGKNLSE-NALKKVNMLVVPLIGFGSLLIA-LFPQQLLAWFIWAALSLMTNCFF 410

Query: 419 VIVILTLFWKRFHGKAVPPTIIAGLLFTVFWIS--------SGLDAKVSVRLMNFIVTFI 470
             ++L L+W R    A   ++IAG + T+   +        +G+ A  SV L  F+ +F+
Sbjct: 411 FPIMLGLYWDRMTKNAARLSMIAGFVVTLATFAIYGKTIYIAGIPA-YSV-LPGFVASFV 468

Query: 471 VAI 473
           +A+
Sbjct: 469 LAV 471


>gb|AAG20007.1| (AE005081) pantothenate permease; PanF [Halobacterium sp. NRC-1]
           Length = 482
           
 Score = 97.9 bits (240), Expect = 2e-19
 Identities = 104/416 (25%), Positives = 191/416 (45%), Gaps = 23/416 (5%)

Query: 19  ISVGIYQGRKA-KSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGFAFAAGLAAIW 77
           ++VG+   R   +  +D+ +AGR L   V   +  AT  SA+     P  A+A G   I 
Sbjct: 5   LAVGLVAYRVTDRDAEDYYLAGRGLGTGVLLFTTFATLLSAFTFFAGPNIAYANGPEWIL 64

Query: 78  PAIGCVLGII--VAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRILGSATIAFF 135
             +G + G++  + W V   R     +    VT  + +  R     + +R L +    F+
Sbjct: 65  -VMGLMDGVLFGLLWYVLGYRQWLLGKANGYVTLGEMLGDRF--GSRGLRGLVAGVSIFW 121

Query: 136 FFFYVGAQYLGGGKVLNTLFG--LDPKLGMLITALVILPYTVMGGLKSVAYTDTVQAIVM 193
            F YV  Q +G G+ L  L G  +    G     L ++ Y  + G++ VA+TDT+Q + M
Sbjct: 122 LFPYVMLQQIGAGEALVGLTGGAVPYWAGAGFITLFMVVYVAISGMRGVAWTDTLQGVFM 181

Query: 194 ILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAAIVFVIAEFSWF 253
           +       I  V ++    E+  T  T  L+ A       LGG  GA +  +++++    
Sbjct: 182 L------GITWVAFVWVAAEIAGT--TGGLAGALPAEFRALGG--GAYSPQWMLSQAIGI 231

Query: 254 FGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGWIGIAIFGPNGLKDP 313
              +   PQ++ RF      +  K    I     ++ ++ A ++G     +  P  L D 
Sbjct: 232 AVGVSMFPQVNQRFFVADSKRTLKRTFAIWPLLVVLLFVPAFLMGAWANGVGLP--LPDG 289

Query: 314 EQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSENILKPYIYKNEADPR 373
           E ++P ++ +  P   AA+ + GA+AAM+S++DS+L+  S+ F+ +I +P++   +A  R
Sbjct: 290 ENIVPILLSEYTPGWFAALVVAGALAAMMSSSDSMLLSGSSYFTRDIYRPFV-NADATAR 348

Query: 374 KSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVIVILTLFWKR 429
           +   + R+   +  + A   + + P  L+   VG T  G     +  V L ++W+R
Sbjct: 349 REDTLGRVGVAAFAVAAFGGSLLRPGSLLE--VGSTAFGGFAQLAPPVALAMYWRR 402


>pir||T03475 transmembrane protein - Rhodobacter capsulatus
           >gi|3128276|gb|AAC16128.1| (AF010496) transmembrane
           protein DhlC homolog [Rhodobacter capsulatus]
           Length = 578
           
 Score = 97.1 bits (238), Expect = 4e-19
 Identities = 104/464 (22%), Positives = 195/464 (41%), Gaps = 39/464 (8%)

Query: 8   LAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGF 67
           +A+  F++   + +  +   + KS  DF  AG  + G+   L+      SA   LG+   
Sbjct: 43  IAMFGFFVVATLFITKWAAGRTKSAADFYTAGGGITGFQNGLAIAGDYMSAASFLGISAA 102

Query: 68  AFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRIL 127
               G   +  +IG ++G  +   + A RLR   +     TF D  A   P A+  +R+ 
Sbjct: 103 VMLQGYDGLIYSIGFLVGWPILTFLMAERLRNLGK----FTFADVAA--FPFAQTPVRVF 156

Query: 128 GSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTDT 187
            + +      FY+ AQ +G G+++  LFGL+    +++  ++++ Y + GG+ +  +   
Sbjct: 157 AAMSTLVVVAFYLIAQMVGAGQLIKLLFGLEYLYAVIVVGILMMVYVLFGGMTATTWVQI 216

Query: 188 VQAIVMI-LTLIVAPIVGVIYIANHPELYATSVTA----ALSKAGVKYSTILGGMAGAAA 242
           ++A +++     +A +V V Y  +   L+A SV      AL+           G++    
Sbjct: 217 IKACLLLGGASFMALMVMVHYGFSLESLFADSVKVKTDLALAAGKTPEEAAAAGISIMGP 276

Query: 243 IVFV---IAEFSW----FFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGAL 295
             FV   I+  S+     FG   G+P + +RF  +   K A+ +      W    Y+   
Sbjct: 277 GTFVKDPISAISFGMALMFG-TAGLPHILMRFFTVPSAKEARKSVMWATVWIGYFYMLTF 335

Query: 296 MIGWIGIAIFGPN-GLKDPEQVMPSVMLKLFPPALAAVFITGAV--------------AA 340
           +IG+  I     N GL   +      +  +    +AA+ +  AV              A 
Sbjct: 336 IIGFGAIVYVLTNPGLVSYD--AKGALTLVGGNNMAAIHLAQAVGGNIFLGFISAVAFAT 393

Query: 341 MLSTADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSH 400
           +L+    L +  ++  S ++        +AD    L VSR+TT+ LGI+A+++       
Sbjct: 394 ILAVVAGLTLSGASAVSHDLYSTVFKNGKADSASELRVSRITTICLGIVAVVLGLAFEKQ 453

Query: 401 LIYTIVGYTWAGIGDTFSVIVILTLFWKRFHGKAVPPTIIAGLL 444
            I  +V   +A        ++ ++L WK   G      +I G L
Sbjct: 454 NIAFMVSLAFAIAASANFPVLFMSLLWK---GMTTRGAVIGGSL 494


>gi|4507035 solute carrier family 5 (sodium iodide symporter), member 5 [Homo
           sapiens] >gi|11526040|ref|XP_009295.1| solute carrier
           family 5 (sodium iodide symporter), member 5 [Homo
           sapiens] >gi|2136179|pir||JC4974 sodium iodide symporter
           - human >gi|1628579|gb|AAB17378.1| (U66088) sodium
           iodide symporter [Homo sapiens]
           >gi|3702269|gb|AAC62827.1| (AC005796) sodium iodide
           symporter [Homo sapiens]
           Length = 643
           
 Score = 96.3 bits (236), Expect = 7e-19
 Identities = 98/408 (24%), Positives = 172/408 (42%), Gaps = 49/408 (12%)

Query: 12  VFYLGFLIS------VGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLP 65
           VF L  L+S      VG+ +G + +S +DF   GR+L      LS  A+  SA  +LG+P
Sbjct: 19  VFALMLLVSTGIGLWVGLARGGQ-RSAEDFFTGGRRLAALPVGLSLSASFMSAVQVLGVP 77

Query: 66  GFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIR 125
             A+  GL  +W  +G +L  ++   +F     +        +  +Y+  R   A   +R
Sbjct: 78  SEAYRYGLKFLWMCLGQLLNSVLTALLFMPVFYR----LGLTSTYEYLEMRFSRA---VR 130

Query: 126 ILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYT 185
           + G+         Y G        +LN + GLD    +L T ++   YT +GG+K+V +T
Sbjct: 131 LCGTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTAVGGMKAVVWT 190

Query: 186 DTVQAIVMILTLIVAPIVGVIYIA----------NHPELYATSVTAALSKAGVKYSTILG 235
           D  Q +VM+    V    GV+ +           NH  +               ++ ++G
Sbjct: 191 DVFQVVVMLSGFWVVLARGVMLVGGPRQVLTLAQNHSRINLMDFNPDPRSRYTFWTFVVG 250

Query: 236 GMAGAAAIVFVIAEFSWFFGYLGGMPQLSI-RFMAIKDDKNAKLARNIGIGWTIIAYIGA 294
           G               W   Y  G+ Q  + R++A + +K AKLA  I      +    A
Sbjct: 251 G------------TLVWLSMY--GVNQAQVQRYVACRTEKQAKLALLINQVGLFLIVSSA 296

Query: 295 LMIGWIGIAIFGP------NGLKDPEQVMPSVMLKLFP--PALAAVFITGAVAAMLSTAD 346
              G +    +          +  P+Q MP ++L +F   P +  +F+  A +  LSTA 
Sbjct: 297 ACCGIVMFVFYTDCDPLLLGRISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTAS 356

Query: 347 SLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMA 394
           + +   +    E+++KP +      PRK +++S+  ++  G   L +A
Sbjct: 357 TSINAMAAVTVEDLIKPRL--RSLAPRKLVIISKGLSLIYGSACLTVA 402


>gi|11498804 pantothenate permease (panF-2) [Archaeoglobus fulgidus]
           >gi|7442767|pir||D69400 pantothenate permease (panF-2)
           homolog - Archaeoglobus fulgidus
           >gi|2649380|gb|AAB90040.1| (AE001021) pantothenate
           permease (panF-2) [Archaeoglobus fulgidus]
           Length = 474
           
 Score = 96.0 bits (235), Expect = 9e-19
 Identities = 110/444 (24%), Positives = 195/444 (43%), Gaps = 35/444 (7%)

Query: 12  VFYLGFLISVGIY-QGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGFAFA 70
           +++L   + VG Y   R  KS +D+ +A R L      ++   T      +LG+   A+ 
Sbjct: 1   MYFLVTTLGVGFYLMKRMEKSEEDYLVAKRGLGAVPVGVTLALTVLGTPHILGVMESAYD 60

Query: 71  AGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRILGSA 130
            GL A+W +    + + +   +F GR  ++ +      F+D I   +     W+R++  A
Sbjct: 61  IGLPAVWFSFAHAIMLAIV-CLFTGRWARKLKVESVPEFLDVIFSNY-----WLRLMVGA 114

Query: 131 TIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTDTVQA 190
            IA   F     +  G G  ++ L G   ++G++I AL+ + Y V+ G+K VA+ + + A
Sbjct: 115 VIAGAIFGICTLETQGLGVFVSILTGTSIEVGIVIGALIGILYVVLSGMKEVAWLNVLNA 174

Query: 191 IVMILTLIVAPIVGVIYIANH----PELYATSVTAALSKAGVKYSTILGGMAGAAAIVFV 246
           +++ + +I A  V    + N      E Y ++  A        +   +G      A+V V
Sbjct: 175 VILYIGIIAATFVLGSGLQNGWEGVNEFYISNDLAGKLNIFGSWEVFVG-----FALVNV 229

Query: 247 IAEFSWFFGYLGGMPQLSIR-FMAIKDDKNAKLARNIGIGWTIIAYIGALMIGWIGIAI- 304
           +A       +  G+ Q  +   +A K     + A  I +       + A ++G    A  
Sbjct: 230 LATV-----FFQGISQQGLHAALAAKSPDVLRKAMLIAVPVNGSFAVFAAVMGMAARATP 284

Query: 305 -FGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSENILKP 363
            F   G K      P++++ + P   +A+ +   + A+LS+    L+  +T F  +I K 
Sbjct: 285 EFAELGAK---TATPAMIVSVLPTWASALLLATCLVAVLSSYAITLLAPTTIFVNDIYKA 341

Query: 364 YIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVIVIL 423
            + K  A   + L +SR+ TV L + ALI A  +P  L   +  ++W      F   VI 
Sbjct: 342 -VLKPNASHEELLRLSRILTVLLAVAALIPAVSLPPILAAMMWLFSWLVPVFWF---VIF 397

Query: 424 TLFWKRFHGKAVPPTIIAGLLFTV 447
            LFWKR    + P  II  LL  V
Sbjct: 398 GLFWKR----SAPAAIITCLLVWV 417


>dbj|BAA24835.1| (D87920) sodium iodide symporter [Homo sapiens]
           Length = 643
           
 Score = 96.0 bits (235), Expect = 9e-19
 Identities = 98/408 (24%), Positives = 172/408 (42%), Gaps = 49/408 (12%)

Query: 12  VFYLGFLIS------VGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLP 65
           VF L  L+S      VG+ +G + +S +DF   GR+L      LS  A+  SA  +LG+P
Sbjct: 19  VFALMLLVSTGIGLWVGLARGGQ-RSAEDFFTGGRRLAALPVGLSLSASFMSAVQVLGVP 77

Query: 66  GFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIR 125
             A+  GL  +W  +G +L  ++   +F     +        +  +Y+  R   A   +R
Sbjct: 78  SEAYRYGLKFLWMCLGQLLNSVLTPLLFMPVFYR----LGLTSTYEYLEMRFSRA---VR 130

Query: 126 ILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYT 185
           + G+         Y G        +LN + GLD    +L T ++   YT +GG+K+V +T
Sbjct: 131 LCGTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTAVGGMKAVVWT 190

Query: 186 DTVQAIVMILTLIVAPIVGVIYIA----------NHPELYATSVTAALSKAGVKYSTILG 235
           D  Q +VM+    V    GV+ +           NH  +               ++ ++G
Sbjct: 191 DVFQVVVMLSGFWVVLARGVMLVGGPRQVLTLAQNHSRINLMDFNPDPRSRYTFWTFVVG 250

Query: 236 GMAGAAAIVFVIAEFSWFFGYLGGMPQLSI-RFMAIKDDKNAKLARNIGIGWTIIAYIGA 294
           G               W   Y  G+ Q  + R++A + +K AKLA  I      +    A
Sbjct: 251 G------------TLVWLSMY--GVNQAQVQRYVACRTEKQAKLALLINQVGLFLIVSSA 296

Query: 295 LMIGWIGIAIFGP------NGLKDPEQVMPSVMLKLFP--PALAAVFITGAVAAMLSTAD 346
              G +    +          +  P+Q MP ++L +F   P +  +F+  A +  LSTA 
Sbjct: 297 ACCGIVMFVFYTDCDPLLLGRISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTAS 356

Query: 347 SLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMA 394
           + +   +    E+++KP +      PRK +++S+  ++  G   L +A
Sbjct: 357 TSINAMAAVTVEDLIKPRL--RSLAPRKLVIISKGLSLIYGSACLTVA 402


>emb|CAB88444.1| (AL353815) putative sodium-coupled permease [Streptomyces
           coelicolor A3(2)]
           Length = 527
           
 Score = 95.2 bits (233), Expect = 2e-18
 Identities = 113/505 (22%), Positives = 213/505 (41%), Gaps = 56/505 (11%)

Query: 9   AVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGFA 68
           +VL+ Y   ++++G++  ++     DF  AG ++P W++ +S   +G SA    G  G A
Sbjct: 7   SVLIGYFAVMVAIGVWSHKRVDDVSDFFTAGGKMPWWLSGISHHMSGYSAVMFTGYAGIA 66

Query: 69  FAAGLAAI--WPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRH----PEAEK 122
           +  G+ +   W +    LG+ +   +FA R+ +   +    + ++Y+  R+     +A  
Sbjct: 67  YTYGVTSFVTW-SFPIALGVAIGSKLFAPRINRLRSRLHVASPLEYLKNRYNLPTQQALA 125

Query: 123 WIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSV 182
           W  +L            V A++     +L+   G+    G+LIT ++   Y  +GGL + 
Sbjct: 126 WSGML-------LKIVDVAAKWAAIATLLSVFTGITLNQGILITGVITGIYCTIGGLWAD 178

Query: 183 AYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAA 242
           A T+  Q I+ +L  +   +  V+ + +H   +      AL   G         + G   
Sbjct: 179 ALTELGQFIIQLLAGVAMFVAVVMKLGDHGGFFGVWDEPALQGHGKP-------LVGPYG 231

Query: 243 IVFVIA-EFSWFFGYLGGMPQLSIRFMAIKD----DKNAKLARNIGIGWTIIAYIGALMI 297
            VF++A  F   F Y GGM   + R+MA  +     + A+L+  + + W ++ +    M 
Sbjct: 232 TVFLLAFLFIKLFEYNGGMLNQAQRYMATANAREATRGARLSAVLWLVWPLVLFFPMWM- 290

Query: 298 GWIGIAIFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFS 357
                 +   +   D       +  +L P  L  + I G  +  ++   S     +  F+
Sbjct: 291 ----SPLLVESQKADGSDSYALMTEQLLPHGLLGLVIVGFFSHTMAMCSSDANAIAAVFT 346

Query: 358 ENILKPYIYKNEA--DPRKSLMVSRLTTVSLGIIALIMAYVVPSHL---IYTIVGYTWAG 412
            ++  P + K       R  L+ +RLTTV    +++ +A  V S     I T+V    AG
Sbjct: 347 RDV-APVLSKRARGWGQRSGLLAARLTTVIFLGLSMAVATQVDSPTFKDIITVVIKWVAG 405

Query: 413 IGDTFSVIVILTLFWKRFHGKAVPPTIIA--GLLFTVFWISS-----------GLDAKVS 459
           +    ++ ++L L   R   ++ P   +   GL    FW+ +            L+ +VS
Sbjct: 406 LMGPIAIPMMLGLL--RPFRRSGPTAALTSWGLGLVAFWLVNYPINWSVDGGVPLEYQVS 463

Query: 460 VRLMNFIVTFIVAIIATYAIKPEKT 484
           V L       +V  IA   +KPE T
Sbjct: 464 VPL----AVSLVLYIAIGYLKPEDT 484


>emb|CAC17810.1| (AJ276242) sodium iodide symporter [Sus scrofa]
           Length = 643
           
 Score = 94.8 bits (232), Expect = 2e-18
 Identities = 110/475 (23%), Positives = 200/475 (41%), Gaps = 64/475 (13%)

Query: 12  VFYLGFLIS------VGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLP 65
           VF L  L+S      VG+ +G + +S +DF   GR+L      LS  A+  SA  +LG+P
Sbjct: 19  VFALMLLVSTGIGLWVGLARGGQ-RSAEDFFTGGRRLTAVPVGLSLSASFMSAVQVLGVP 77

Query: 66  GFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIR 125
             A+  GL  +W  +G +L  ++   +F     +        +   Y+  R   A   +R
Sbjct: 78  AEAYRYGLKFLWMCLGQLLNSLLTALLFLPVFYR----LGLTSTYQYLELRFSRA---VR 130

Query: 126 ILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYT 185
           + G+         Y G        +LN + GLD    +L T ++   YT +GG+K+V +T
Sbjct: 131 LCGTLQYLVATMLYTGVVIYAPALILNQVTGLDIWASLLSTGIICTFYTTVGGMKAVIWT 190

Query: 186 DTVQAIVMILTLIVAPIVGVIYIA----------NHPELYATSVTAALSKAGVKYSTILG 235
           D  Q +VM+    V    G + +           NH  +          +    ++ ++G
Sbjct: 191 DVFQVLVMLTGFWVVLARGTVLVGGPGRVLELAKNHSRINLMDFDLDPRRRYTFWTFVVG 250

Query: 236 GMAGAAAIVFVIAEFSWFFGYLGGMPQLSI-RFMAIKDDKNAKLARNIGIGWTIIAYIGA 294
           G               W   Y  G+ Q  + R++A + +K AKLA  I      +    A
Sbjct: 251 G------------TLVWLSMY--GVNQAQVQRYVACRTEKQAKLALLINQVGLFLIVSSA 296

Query: 295 LMIGWIGIAIFG------PNGLKDPEQVMPSVMLKLFP--PALAAVFITGAVAAMLSTAD 346
              G +  A++          +  P+Q MP ++L +F   P +  +F+  A +  LSTA 
Sbjct: 297 AACGIVMFALYVDCDPLLAGHISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTAS 356

Query: 347 SLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLI---- 402
           + +   +    E+++KP +      PR+ +++S+  ++  G   L +A +  S L+    
Sbjct: 357 TSINAMAAVTVEDLIKPRL--PNLAPRRLVIISKGLSLIYGSACLTVAAL--SSLLGGGV 412

Query: 403 ----YTIVGYTWAGIGDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453
               +T++G     +   F    +L +F    +   V   + AGL  ++ W++ G
Sbjct: 413 LQGSFTVMGVISGPLLGAF----VLGMFLPSCNTSGVLSGLAAGLALSL-WVAVG 462


>emb|CAC17816.1| (AJ276292) sodium iodide symporter [Sus scrofa]
           Length = 636
           
 Score = 94.8 bits (232), Expect = 2e-18
 Identities = 110/475 (23%), Positives = 200/475 (41%), Gaps = 64/475 (13%)

Query: 12  VFYLGFLIS------VGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLP 65
           VF L  L+S      VG+ +G + +S +DF   GR+L      LS  A+  SA  +LG+P
Sbjct: 19  VFALMLLVSTGIGLWVGLARGGQ-RSAEDFFTGGRRLTAVPVGLSLSASFMSAVQVLGVP 77

Query: 66  GFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIR 125
             A+  GL  +W  +G +L  ++   +F     +        +   Y+  R   A   +R
Sbjct: 78  AEAYRYGLKFLWMCLGQLLNSLLTALLFLPVFYR----LGLTSTYQYLELRFSRA---VR 130

Query: 126 ILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYT 185
           + G+         Y G        +LN + GLD    +L T ++   YT +GG+K+V +T
Sbjct: 131 LCGTLQYLVATMLYTGVVIYAPALILNQVTGLDIWASLLSTGIICTFYTTVGGMKAVIWT 190

Query: 186 DTVQAIVMILTLIVAPIVGVIYIA----------NHPELYATSVTAALSKAGVKYSTILG 235
           D  Q +VM+    V    G + +           NH  +          +    ++ ++G
Sbjct: 191 DVFQVLVMLTGFWVVLARGTVLVGGPGRVLELAKNHSRINLMDFDLDPRRRYTFWTFVVG 250

Query: 236 GMAGAAAIVFVIAEFSWFFGYLGGMPQLSI-RFMAIKDDKNAKLARNIGIGWTIIAYIGA 294
           G               W   Y  G+ Q  + R++A + +K AKLA  I      +    A
Sbjct: 251 G------------TLVWLSMY--GVNQAQVQRYVACRTEKQAKLALLINQVGLFLIVSSA 296

Query: 295 LMIGWIGIAIFG------PNGLKDPEQVMPSVMLKLFP--PALAAVFITGAVAAMLSTAD 346
              G +  A++          +  P+Q MP ++L +F   P +  +F+  A +  LSTA 
Sbjct: 297 AACGIVMFALYVDCDPLLAGHISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTAS 356

Query: 347 SLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLI---- 402
           + +   +    E+++KP +      PR+ +++S+  ++  G   L +A +  S L+    
Sbjct: 357 TSINAMAAVTVEDLIKPRL--PNLAPRRLVIISKGLSLIYGSACLTVAAL--SSLLGGGV 412

Query: 403 ----YTIVGYTWAGIGDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453
               +T++G     +   F    +L +F    +   V   + AGL  ++ W++ G
Sbjct: 413 LQGSFTVMGVISGPLLGAF----VLGMFLPSCNTSGVLSGLAAGLALSL-WVAVG 462


>gi|11141885 solute carrier family 5 (choline transporter), member 7; high
           affinity choline transporter; hemicholinium-3-sensitive
           choline transporter [Homo sapiens]
           >gi|9843754|emb|CAC03717.1| (AJ401466) high affinity
           choline transporter [Homo sapiens]
           >gi|10998442|gb|AAG25940.1| (AF276871) high affinity
           choline transporter [Homo sapiens]
           >gi|11231081|dbj|BAB18161.1| (AB043997) high-affinity
           choline transporter CHT1 [Homo sapiens]
           Length = 580
           
 Score = 92.4 bits (226), Expect = 1e-17
 Identities = 102/434 (23%), Positives = 188/434 (42%), Gaps = 58/434 (13%)

Query: 7   ILAVLVFYLGFLISVGIYQGRKAKSH-------KDFSIAGRQLPGWVAALSERATGESAW 59
           ++A++VFYL  L+ VGI+   + K+        +   + GR +   V   +  AT     
Sbjct: 8   LIAIIVFYLLILL-VGIWAAWRTKNSGSAEERSEAIIVGGRDIGLLVGGFTMTATWVGGG 66

Query: 60  CLLGLPGFAFAAGLAAIWPA--IGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRH 117
            + G     +  G    W    IG  L +I+    FA  +R +        F     KR 
Sbjct: 67  YINGTAEAVYVPGYGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQIYGKRM 126

Query: 118 PEAEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMG 177
                   ++G         F+  A +   G  ++ +  +D  + ++I+AL+   YT++G
Sbjct: 127 GGLLFIPALMGE-------MFWAAAIFSALGATISVIIDVDMHISVIISALIATLYTLVG 179

Query: 178 GLKSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGM 237
           GL SVAYTD VQ    +  + V   + V +  +HP +     TA       KY     G 
Sbjct: 180 GLYSVAYTDVVQ----LFCIFVGLWISVPFALSHPAVADIGFTA----VHAKYQKPWLGT 231

Query: 238 AGAAAIVFVIAEFSWFFGY----LGGMPQLSI--RFMAIKDDKNAKLARNIGIGWTIIAY 291
             ++ +      +SW   +    LGG+P  +   R ++      A++   +     ++  
Sbjct: 232 VDSSEV------YSWLDSFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMA 285

Query: 292 IGALMIGWIGIA---------IFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAV-AAM 341
           I A++IG IG +         +  P   ++ + ++P ++L+   P   + F  GAV AA+
Sbjct: 286 IPAILIGAIGASTDWNQTAYGLPDPKTTEEADMILP-IVLQYLCPVYISFFGLGAVSAAV 344

Query: 342 LSTADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMA------- 394
           +S+ADS ++ +S+ F+ NI +    +N +D ++ + V R+T    G  A  MA       
Sbjct: 345 MSSADSSILSASSMFARNIYQLSFRQNASD-KEIVWVMRITVFVFGASATAMALLTKTVY 403

Query: 395 --YVVPSHLIYTIV 406
             + + S L+Y ++
Sbjct: 404 GLWYLSSDLVYIVI 417


>sp|P96169|SGLT_VIBPA SODIUM/GLUCOSE COTRANSPORTER (NA(+)/GLUCOSE SYMPORTER)
           >gi|8886895|gb|AAF80602.1|AF255301_1 (AF255301)
           Na+/galactose cotransporter SGLT [Vibrio
           parahaemolyticus]
           Length = 543
           
 Score = 92.1 bits (225), Expect = 1e-17
 Identities = 112/470 (23%), Positives = 192/470 (40%), Gaps = 42/470 (8%)

Query: 8   LAVLVFYLGFLISVGIYQGRKAK----SHKDFSIAGRQLPGWVAALSERATGESAWCLLG 63
           + V   Y+  +I VG++  R  K    S +D+ +AG+ LP W    S  A   SA   +G
Sbjct: 13  IMVFAIYVAIIIGVGLWVSRDKKGTQKSTEDYFLAGKSLPWWAVGASLIAANISAEQFIG 72

Query: 64  LPGFAFAAGLA-AIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEK 122
           + G  ++ GLA A +  +  +  IIV        + K        T  +++ KR  +  K
Sbjct: 73  MSGSGYSIGLAIASYEWMSAITLIIVGKYFLPIFIEK-----GIYTIPEFVEKRFNKKLK 127

Query: 123 WIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSV 182
              IL    I+ + F  + +    GG  L T+ G+     +L  AL  L Y++ GGL +V
Sbjct: 128 --TILAVFWISLYIFVNLTSVLYLGGLALETILGIPLMYSILGLALFALVYSIYGGLSAV 185

Query: 183 AYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILG------- 235
            +TD +Q   ++L   +   + V +I      +A  V+  +  A   +  IL        
Sbjct: 186 VWTDVIQVFFLVLGGFMTTYMAVSFIGGTDGWFA-GVSKMVDAAPGHFEMILDQSNPQYM 244

Query: 236 GMAGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAK---------------LAR 280
            + G A ++  +   + +  Y G    +  R +A K    A+               L  
Sbjct: 245 NLPGIAVLIGGLWVANLY--YWGFNQYIIQRTLAAKSVSEAQKGIVFAAFLKLIVPFLVV 302

Query: 281 NIGIGWTIIAYIGALMIGWIGIAIFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAA 340
             GI   +I     LM     IA        + ++  P  + +  P  +  V      AA
Sbjct: 303 LPGIAAYVITSDPQLMASLGDIAATNLPSAANADKAYP-WLTQFLPVGVKGVVFAALAAA 361

Query: 341 MLSTADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVP-- 398
           ++S+  S+L  ++T F+ +I K YI  +  D  K + V R   V   IIA ++A ++   
Sbjct: 362 IVSSLASMLNSTATIFTMDIYKEYISPDSGD-HKLVNVGRTAAVVALIIACLIAPMLGGI 420

Query: 399 SHLIYTIVGYTWAGIGDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVF 448
                 I  YT   +      + +L LFWK+   K     ++A + F +F
Sbjct: 421 GQAFQYIQEYTGL-VSPGILAVFLLGLFWKKTTSKGAIIGVVASIPFALF 469


>dbj|BAA11215.1| (D78137) Na+/glucose symporter [Vibrio parahaemolyticus]
           Length = 530
           
 Score = 91.7 bits (224), Expect = 2e-17
 Identities = 112/468 (23%), Positives = 191/468 (39%), Gaps = 42/468 (8%)

Query: 10  VLVFYLGFLISVGIYQGRKAK----SHKDFSIAGRQLPGWVAALSERATGESAWCLLGLP 65
           V   Y+  +I VG++  R  K    S +D+ +AG+ LP W    S  A   SA   +G+ 
Sbjct: 2   VFAIYVAIIIGVGLWVSRDKKGTQKSTEDYFLAGKSLPWWAVGASLIAANISAEQFIGMS 61

Query: 66  GFAFAAGLA-AIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWI 124
           G  ++ GLA A +  +  +  IIV        + K        T  +++ KR  +  K  
Sbjct: 62  GSGYSIGLAIASYEWMSAITLIIVGKYFLPIFIEK-----GIYTIPEFVEKRFNKKLK-- 114

Query: 125 RILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAY 184
            IL    I+ + F  + +    GG  L T+ G+     +L  AL  L Y++ GGL +V +
Sbjct: 115 TILAVFWISLYIFVNLTSVLYLGGLALETILGIPLMYSILGLALFALVYSIYGGLSAVVW 174

Query: 185 TDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILG-------GM 237
           TD +Q   ++L   +   + V +I      +A  V+  +  A   +  IL         +
Sbjct: 175 TDVIQVFFLVLGGFMTTYMAVSFIGGTDGWFA-GVSKMVDAAPGHFEMILDQSNPQYMNL 233

Query: 238 AGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAK---------------LARNI 282
            G A ++  +   + +  Y G    +  R +A K    A+               L    
Sbjct: 234 PGIAVLIGGLWVANLY--YWGFNQYIIQRTLAAKSVSEAQKGIVFAAFLKLIVPFLVVLP 291

Query: 283 GIGWTIIAYIGALMIGWIGIAIFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAML 342
           GI   +I     LM     IA        + ++  P  + +  P  +  V      AA++
Sbjct: 292 GIAAYVITSDPQLMASLGDIAATNLPSAANADKAYP-WLTQFLPVGVKGVVFAALAAAIV 350

Query: 343 STADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVP--SH 400
           S+  S+L  ++T F+ +I K YI  +  D  K + V R   V   IIA ++A ++     
Sbjct: 351 SSLASMLNSTATIFTMDIYKEYISPDSGD-HKLVNVGRTAAVVALIIACLIAPMLGGIGQ 409

Query: 401 LIYTIVGYTWAGIGDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVF 448
               I  YT   +      + +L LFWK+   K     ++A + F +F
Sbjct: 410 AFQYIQEYTGL-VSPGILAVFLLGLFWKKTTSKGAIIGVVASIPFALF 456


>gi|11528510 solute carrier family 5 (choline transporter), member 7 [Mus
           musculus] >gi|9843809|emb|CAC03719.1| (AJ401467) high
           affinity choline transporter [Mus musculus]
           Length = 580
           
 Score = 91.7 bits (224), Expect = 2e-17
 Identities = 110/467 (23%), Positives = 202/467 (42%), Gaps = 55/467 (11%)

Query: 7   ILAVLVFYLGFLISVGIYQGRKAKS------HKD-FSIAGRQLPGWVAALSERATGESAW 59
           ++A+++FYL  +  VGI+   K K+      H +   + GR +   V   +  AT     
Sbjct: 8   LVAIILFYL-LIFLVGIWAAWKTKNSGNPEEHSEAIIVGGRDIGLLVGGFTMTATWVGGG 66

Query: 60  CLLGLPGFAFAAGLAAIWPA--IGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRH 117
            + G     +  G    W    IG  L +I+    FA  +R +        F     KR 
Sbjct: 67  YINGTAVAVYGPGCGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQIYGKRM 126

Query: 118 PEAEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMG 177
                   ++G         F+  A +   G  ++ +  +D  + ++++AL+ + YT++G
Sbjct: 127 GGLLFIPALMGE-------MFWAAAIFSALGATISVIIDVDVNISVIVSALIAILYTLVG 179

Query: 178 GLKSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGM 237
           GL SVAYTD VQ   + + L ++    V +  +HP +     TA  +K     S  LG +
Sbjct: 180 GLYSVAYTDVVQLFCIFIGLWIS----VPFALSHPAVTDIGFTAVHAK---YQSPWLGTI 232

Query: 238 AGAAAIVFVIAEFSWFFGY----LGGMPQLSI--RFMAIKDDKNAKLARNIGIGWTIIAY 291
                    +  ++W   +    LGG+P  +   R ++      A++   +     ++  
Sbjct: 233 ES-------VEVYTWLDNFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSYLAAFGCLVMA 285

Query: 292 IGALMIGWIGIA------IFG---PNGLKDPEQVMPSVMLKLFPPALAAVFITGAV-AAM 341
           + A+ IG IG +       +G   P   ++ + ++P ++L+   P   + F  GAV AA+
Sbjct: 286 LPAICIGAIGASTDWNQTAYGYPDPKTKEEADMILP-IVLQYLCPVYISFFGLGAVSAAV 344

Query: 342 LSTADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHL 401
           +S+ADS ++ +S+ F+ NI +    +N +D ++ + V R+T +  G  A  MA      L
Sbjct: 345 MSSADSSILSASSMFARNIYQLSFRQNASD-KEIVWVMRITVLVFGASATAMAL-----L 398

Query: 402 IYTIVGYTWAGIGDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVF 448
             T+ G  W    D   +I+   L    F         +AG +F +F
Sbjct: 399 TKTVYG-LWYLSSDLVYIIIFPQLLCVLFIKGTNTYGAVAGYIFGLF 444


>gb|AAG36945.1| (AF276872) sodium and chloride-dependent high-affinity choline
           transporter [Mus musculus]
           Length = 580
           
 Score = 91.3 bits (223), Expect = 2e-17
 Identities = 109/467 (23%), Positives = 201/467 (42%), Gaps = 55/467 (11%)

Query: 7   ILAVLVFYLGFLISVGIYQGRKAKSHKD-------FSIAGRQLPGWVAALSERATGESAW 59
           ++A+++FYL  +  VGI+   K K+  +         + GR +   V   +  AT     
Sbjct: 8   LVAIILFYL-LIFLVGIWAAWKTKNSGNPEERSEAIIVGGRDIGLLVGGFTMTATWVGGG 66

Query: 60  CLLGLPGFAFAAGLAAIWP--AIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRH 117
            + G     +  G    W    IG  L +I+    FA  +R +        F     KR 
Sbjct: 67  YINGTAEAVYGPGCGLAWAHAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFKQIYGKRM 126

Query: 118 PEAEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMG 177
                   ++G         F+  A +   G  ++ +  +D  + ++++AL+ + YT++G
Sbjct: 127 GGLLFIPALMGE-------MFWAAAIFSALGATISVIIDVDVNISVIVSALIAILYTLVG 179

Query: 178 GLKSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGM 237
           GL SVAYTD VQ   + + L ++    V +  +HP +     TA  +K     S  LG +
Sbjct: 180 GLYSVAYTDVVQLFCIFIGLWIS----VPFALSHPAVTDIGFTAVHAK---YQSPWLGTI 232

Query: 238 AGAAAIVFVIAEFSWFFGY----LGGMPQLSI--RFMAIKDDKNAKLARNIGIGWTIIAY 291
                    +  ++W   +    LGG+P  +   R ++      A++   +     ++  
Sbjct: 233 ES-------VEVYTWLDNFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMA 285

Query: 292 IGALMIGWIGIA------IFG---PNGLKDPEQVMPSVMLKLFPPALAAVFITGAV-AAM 341
           + A+ IG IG +       +G   P   ++ + ++P ++L+   P   + F  GAV AA+
Sbjct: 286 LPAICIGAIGASTDWNQTAYGYPDPKTKEEADMILP-IVLQYLCPVYISFFGLGAVSAAV 344

Query: 342 LSTADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHL 401
           +S+ADS ++ +S+ F+ NI +    +N +D ++ + V R+T +  G  A  MA      L
Sbjct: 345 MSSADSSILSASSMFARNIYQLSFRQNASD-KEIVWVMRITVLVFGASATAMAL-----L 398

Query: 402 IYTIVGYTWAGIGDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVF 448
             T+ G  W    D   +I+   L    F         +AG +F +F
Sbjct: 399 TKTVYG-LWYLSSDLVYIIIFPQLLCVLFIKGTNTYGAVAGYIFGLF 444


>dbj|BAA90483.1| (AB030946) high-affinity choline transporter CHO-1 [Caenorhabditis
           elegans]
           Length = 576
           
 Score = 90.9 bits (222), Expect = 3e-17
 Identities = 102/426 (23%), Positives = 185/426 (42%), Gaps = 62/426 (14%)

Query: 7   ILAVLVFYLGFLISVGIYQGRKAKSHKDFS-----------IAGRQLPGWVAALSERATG 55
           I+A++ FY+  L+ VGI+ GRK+KS K+             +AGR +   V   +  AT 
Sbjct: 7   IVAIVFFYVLILV-VGIWAGRKSKSSKELESEAGAATEEVMLAGRNIGTLVGIFTMTATW 65

Query: 56  ESAWCLLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAK 115
                + G     +  GL      +G  + +++   +FA ++R+E           YI  
Sbjct: 66  VGGAYINGTAEALYNGGLLGCQAPVGYAISLVMGGLLFAKKMREEG----------YITM 115

Query: 116 RHPEAEKWIRILGSATIAFFFF---FYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILP 172
             P   K+ + +G            F+  A     G  L+ + G+D    + ++A + + 
Sbjct: 116 LDPFQHKYGQRIGGLMYVPALLGETFWTAAILSALGATLSVILGIDMNASVTLSACIAVF 175

Query: 173 YTVMGGLKSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYST 232
           YT  GG  +VAYTD VQ   + + L V     +++               +S+    +  
Sbjct: 176 YTFTGGYYAVAYTDVVQLFCIFVGLWVCVPAAMVH----------DGAKDISRNAGDWIG 225

Query: 233 ILGGMAGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNI----GIGWTI 288
            +GG    +  +  +          GG+P   + F  +   K A  A+ +    G+G  +
Sbjct: 226 EIGGFKETSLWIDCM-----LLLVFGGIP-WQVYFQRVLSSKTAHGAQTLSFVAGVGCIL 279

Query: 289 IAYIGALMIGWIG------IAIFGP--NGLK----DPEQ---VMPSVMLKLFPPALAAVF 333
           +A I   +IG I       +  + P  NG K     P++   V+P V   L P  +A + 
Sbjct: 280 MA-IPPALIGAIARNTDWRMTDYSPWNNGTKVESIPPDKRNMVVPLVFQYLTPRWVAFIG 338

Query: 334 ITGAVAAMLSTADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIM 393
           +    AA++S+ADS ++ +++ F+ NI K  I +  A  ++ ++V R+  + +GI+A IM
Sbjct: 339 LGAVSAAVMSSADSSVLSAASMFAHNIWKLTI-RPHASEKEVIIVMRIAIICVGIMATIM 397

Query: 394 AYVVPS 399
           A  + S
Sbjct: 398 ALTIQS 403


>dbj|BAA90484.1| (AB030947) high-affinity choline transporter CHT1 [Rattus
           norvegicus]
           Length = 580
           
 Score = 90.5 bits (221), Expect = 4e-17
 Identities = 109/467 (23%), Positives = 200/467 (42%), Gaps = 55/467 (11%)

Query: 7   ILAVLVFYLGFLISVGIYQGRKAKSHKDFS-------IAGRQLPGWVAALSERATGESAW 59
           ++A+++FYL  +  VGI+   K K+  +         + GR +   V   +  AT     
Sbjct: 8   LVAIILFYL-LIFLVGIWAAWKTKNSGNAEERSEAIIVGGRDIGLLVGGFTMTATWVGGG 66

Query: 60  CLLGLPGFAFAAGLAAIWPA--IGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRH 117
            + G     +  G    W    IG  L +I+    FA  +R +        F     KR 
Sbjct: 67  YINGTAEAVYGPGCGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQIYGKRM 126

Query: 118 PEAEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMG 177
                   ++G         F+  A +   G  ++ +  +D  + ++++AL+ + YT++G
Sbjct: 127 GGLLFIPALMGE-------MFWAAAIFSALGATISVIIDVDVNISVIVSALIAILYTLVG 179

Query: 178 GLKSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGM 237
           GL SVAYTD VQ   + + L ++    V +  +HP +     TA  +K     S  LG +
Sbjct: 180 GLYSVAYTDVVQLFCIFIGLWIS----VPFALSHPAVTDIGFTAVHAK---YQSPWLGTI 232

Query: 238 AGAAAIVFVIAEFSWFFGY----LGGMPQLSI--RFMAIKDDKNAKLARNIGIGWTIIAY 291
                    +  ++W   +    LGG+P  +   R ++      A++   +     ++  
Sbjct: 233 ES-------VEVYTWLDNFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMA 285

Query: 292 IGALMIGWIGIA------IFG---PNGLKDPEQVMPSVMLKLFPPALAAVFITGAV-AAM 341
           + A+ IG IG +       +G   P   ++ + ++P ++L+   P   + F  GAV AA+
Sbjct: 286 LPAICIGAIGASTDWNQTAYGFPDPKTKEEADMILP-IVLQYLCPVYISFFGLGAVSAAV 344

Query: 342 LSTADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHL 401
           +S+ADS ++ +S+ F+ NI +    +N +D ++ + V R+T    G  A  MA      L
Sbjct: 345 MSSADSSILSASSMFARNIYQLSFRQNASD-KEIVWVMRITVFVFGASATAMAL-----L 398

Query: 402 IYTIVGYTWAGIGDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVF 448
             T+ G  W    D   +I+   L    F         +AG +F +F
Sbjct: 399 TKTVYG-LWYLSSDLVYIIIFPQLLCVLFIKGTNTYGAVAGYIFGLF 444


>emb|CAB95932.1| (AL359989) putative sodium:solute symporter [Streptomyces
           coelicolor A3(2)]
           Length = 562
           
 Score = 87.8 bits (214), Expect = 3e-16
 Identities = 103/482 (21%), Positives = 192/482 (39%), Gaps = 47/482 (9%)

Query: 10  VLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGFAF 69
           +L  Y   ++ +G    R  ++  DF ++GR LP WV  L+  A    A  +LG+   + 
Sbjct: 25  ILGIYFVVVLGIGFAARRSVRTSLDFFLSGRSLPAWVTGLAFVAANLGATEILGMAANSA 84

Query: 70  AAGLAAI-WPAIGCV-----LGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKW 123
             G+    W  IG +     LG+++    +  ++R   E         ++  R  +A   
Sbjct: 85  QYGVYTTHWYWIGAIPAMVFLGLVMMPFYYGSKVRSVPE---------FLLLRFDKAS-- 133

Query: 124 IRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVA 183
             +L SA  A       G        V+  L G    + +++    +L Y  +GGL S  
Sbjct: 134 -HLLSSALFAIAAILIAGVNLYALAIVVEALLGWPEWVAIVVAGFFVLAYITLGGLSSAI 192

Query: 184 YTDTVQAIVMILTLIVAPIVGVIYIANHPEL-------YATSVTAALSKAGVKYSTILGG 236
           Y + +Q  V++  LI   I+G+  +     L       + +    A    G+     LG 
Sbjct: 193 YNEVLQFFVILAGLIPITILGLKKVGGWDGLSDSLSKSHGSDFMTAWGGTGIGSENPLGA 252

Query: 237 --MAGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGA 294
             +     + FV++   W   +      LS + ++    +   +A    I    +  I  
Sbjct: 253 NWLTIVLGLGFVLSFGYWTTNFAEVQRALSAKNLSAA-QRTPLIAAFPKIFIVFVVMIPG 311

Query: 295 LMIGWIGIAIFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSST 354
           L+   +   I  P         +P +M +L P  +  + +TG +AA ++   + +   +T
Sbjct: 312 LVAAVLVPKIGTPGSDLQYNDAIPYLMQQLLPNGVLGIAVTGLLAAFMAGMAANISSFNT 371

Query: 355 EFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHL--IYTIVGYTWAG 412
            F+ +I + Y+ K+  D    +   RL TV +G++A I    + S    I + +   ++ 
Sbjct: 372 VFTTDIWQKYVVKDRED-GYYVRFGRLITV-IGVLASIGTAFLASSFSNIMSYLQTLFSF 429

Query: 413 IGDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSGLDAKVSVRLMNFIVTFIVA 472
                 V+ I+ +FWKR   K            + FW   GL A  +  ++N+ V +   
Sbjct: 430 FNVPMFVVFIIGMFWKRASMK------------SGFW---GLIAGTTAAMVNYFVIYKQG 474

Query: 473 II 474
           II
Sbjct: 475 II 476


>prf||2204393A Na/I symporter [Rattus norvegicus]
           Length = 618
           
 Score = 86.6 bits (211), Expect = 6e-16
 Identities = 96/404 (23%), Positives = 164/404 (39%), Gaps = 43/404 (10%)

Query: 10  VLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGFAF 69
           +L+   G  + VG+ +G + +S  DF   GRQL      LS  A+  SA  +LG+P  A 
Sbjct: 23  MLLVSTGIGLMVGLARGGQ-RSADDFFTGGRQLAAVPVGLSLAASFMSAVQVLGVPAEAA 81

Query: 70  AAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRILGS 129
             GL  +W   G +L  ++   +F     +        +   Y+  R   A   +R+ G+
Sbjct: 82  RYGLKFLWMCAGQLLNSLLTAFLFLPIFYR----LGLTSTYQYLELRFSRA---VRLCGT 134

Query: 130 ATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTDTVQ 189
                    Y G        +LN + GLD    +L T ++   YT +GG+K+V +TD  Q
Sbjct: 135 LQYLVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTLYTTVGGMKAVVWTDVFQ 194

Query: 190 AIVMILTLIVAPIVGVIYIA----------NHPELYATSVTAALSKAGVKYSTILGGMAG 239
            +VM++   V    GVI +           NH  +               ++  +GG   
Sbjct: 195 VVVMLVGFWVILARGVILLGGPRNVLSLAQNHSRINLMDFDPDPRSRYTFWTFYVGG--- 251

Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSI-RFMAIKDDKNAKLARNIGIGWTIIAYIGALMIG 298
                       W   Y  G+ Q  + R++A   +  AKLA  +      +    A   G
Sbjct: 252 ---------TLVWLSMY--GVNQAQVQRYVACHTEGKAKLALLVNQLGLFLIVASAACCG 300

Query: 299 WIGIAIFG------PNGLKDPEQVMPSVMLKLFP--PALAAVFITGAVAAMLSTADSLLI 350
            +    +          +  P+Q MP ++L +F   P +  +F+  AV+  LSTA + + 
Sbjct: 301 IVMFVYYKDCDPLLTGRISAPDQYMPLLVLDIFEDLPGVPGLFLACAVSGTLSTASTSIN 360

Query: 351 LSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMA 394
             +    E+++KP +      PRK + +S+  +   G   L +A
Sbjct: 361 AMAAVTVEDLIKPRM--PGLAPRKLVFISKGLSFIYGSACLTVA 402


>gi|10863879 solute carrier family 5 (sodium-dependent vitamin transporter),
           member 6 [Homo sapiens]
           >gi|4884550|gb|AAD31727.1|AF069307_1 (AF069307)
           sodium-dependent multivitamin transporter [Homo sapiens]
           >gi|5006365|gb|AAD37481.1|AF081571_1 (AF081571)
           sodium-dependent multi-vitamin transporter [Homo
           sapiens] >gi|5006439|gb|AAD37502.1| (AF116241)
           sodium-dependent multivitamin transporter [Homo sapiens]
           Length = 635
           
 Score = 86.6 bits (211), Expect = 6e-16
 Identities = 115/469 (24%), Positives = 196/469 (41%), Gaps = 51/469 (10%)

Query: 10  VLVFYLGFLISVGIY---QGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPG 66
           V V  L   +++G+Y   +G    +  +  +A R++     ALS  AT +SA  +LG+P 
Sbjct: 31  VFVLLLVLSLAIGLYHACRGWGRHTVGELLMADRKMGCLPVALSLLATFQSAVAILGVPS 90

Query: 67  FAFAAGLAAIWPAIGCV--LGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWI 124
             +  G    W  +GC   LG+++   +F     +        +  +Y+  R     K +
Sbjct: 91  EIYRFG-TQYW-FLGCCYFLGLLIPAHIFIPVFYR----LHLTSAYEYLELRF---NKTV 141

Query: 125 RILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAY 184
           R+ G+ T  F    Y+G         LN + G D  L +L   +V   YT +GGLK+V +
Sbjct: 142 RVCGTVTFIFQMVIYMGVVLYAPSLALNAVTGFDLWLSVLALGIVCTVYTALGGLKAVIW 201

Query: 185 TDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAAIV 244
           TD  Q +VM L  +   IVG   +     ++A +          ++  I G        V
Sbjct: 202 TDVFQTLVMFLGQLAVIIVGSAKVGGLGRVWAVA---------SQHGRISGFELDPDPFV 252

Query: 245 ---FVIAEFSWFFGYLG--GMPQLSI-RFMAIKDDKNAKLARNIGIGWTIIAYIGALMIG 298
              F    F   F  L   G+ Q  + R+++ + +K A L+      +  ++     +IG
Sbjct: 253 RHTFWTLAFGGVFMMLSLYGVNQAQVQRYLSSRTEKAAVLSCYAVFPFQQVSLCVGCLIG 312

Query: 299 WIGIAIFG--PNGLKD----PEQVMPSVMLKLFP--PALAAVFITGAVAAMLSTADSLLI 350
            +  A +   P  ++     P+Q +   ++ L    P L  +FI    +  LST  S   
Sbjct: 313 LVMFAYYQEYPMSIQQAQAAPDQFVLYFVMDLLKGLPGLPGLFIACLFSGSLSTISSAFN 372

Query: 351 LSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTW 410
             +T   E++++P+    E    +++M+SR      G++ L MAY      I + +G   
Sbjct: 373 SLATVTMEDLIRPWF--PEFSEARAIMLSRGLAFGYGLLCLGMAY------ISSQMGPVL 424

Query: 411 AGIGDTFSVI--VILTLF-WKRFHGKAVPPTIIAGL---LFTVFWISSG 453
                 F ++   +L LF    F   A PP  + GL   L   FWI  G
Sbjct: 425 QAAISIFGMVGGPLLGLFCLGMFFPCANPPGAVVGLLAGLVMAFWIGIG 473


>gi|11429441 solute carrier family 5 (sodium-dependent vitamin transporter),
           member 6 [Homo sapiens]
           Length = 635
           
 Score = 86.6 bits (211), Expect = 6e-16
 Identities = 115/469 (24%), Positives = 196/469 (41%), Gaps = 51/469 (10%)

Query: 10  VLVFYLGFLISVGIY---QGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPG 66
           V V  L   +++G+Y   +G    +  +  +A R++     ALS  AT +SA  +LG+P 
Sbjct: 31  VFVLLLVLSLAIGLYHACRGWGRHTVGELLMADRKMGCLPVALSLLATFQSAVAILGVPS 90

Query: 67  FAFAAGLAAIWPAIGCV--LGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWI 124
             +  G    W  +GC   LG+++   +F     +        +  +Y+  R     K +
Sbjct: 91  EIYRFG-TQYW-FLGCCYFLGLLIPAHIFIPVFYR----LHLTSAYEYLELRF---NKTV 141

Query: 125 RILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAY 184
           R+ G+ T  F    Y+G         LN + G D  L +L   +V   YT +GGLK+V +
Sbjct: 142 RVCGTVTFIFQMVIYMGVVLYAPSLALNAVTGFDLWLSVLALGIVCTVYTALGGLKAVIW 201

Query: 185 TDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAAIV 244
           TD  Q +VM L  +   IVG   +     ++A +          ++  I G        V
Sbjct: 202 TDVFQTLVMFLGQLAVIIVGSAKVGGLGRVWAVA---------SQHGRISGFELDPDPFV 252

Query: 245 ---FVIAEFSWFFGYLG--GMPQLSI-RFMAIKDDKNAKLARNIGIGWTIIAYIGALMIG 298
              F    F   F  L   G+ Q  + R+++ + +K A L+      +  ++     +IG
Sbjct: 253 RHTFWTLAFGGVFMMLSLYGVNQAQVQRYLSSRTEKAAVLSCYAVFPFQQVSLCVGCLIG 312

Query: 299 WIGIAIFG--PNGLKD----PEQVMPSVMLKLFP--PALAAVFITGAVAAMLSTADSLLI 350
            +  A +   P  ++     P+Q +   ++ L    P L  +FI    +  LST  S   
Sbjct: 313 LVMFAYYQEYPMSIQQAQAAPDQFVLYFVMDLLKGLPGLPGLFIACLFSGSLSTISSAFN 372

Query: 351 LSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTW 410
             +T   E++++P+    E    +++M+SR      G++ L MAY      I + +G   
Sbjct: 373 SLATVTMEDLIRPWF--PEFSEARAIMLSRGLAFGYGLLCLGMAY------ISSQMGPVL 424

Query: 411 AGIGDTFSVI--VILTLF-WKRFHGKAVPPTIIAGL---LFTVFWISSG 453
                 F ++   +L LF    F   A PP  + GL   L   FWI  G
Sbjct: 425 QAAISIFGMVGGPLLGLFCLGMFFPCANPPGAVVGLLAGLVMAFWIGIG 473


>gb|AAC12270.1| (AF026554) sodium-dependent multi-vitamin transporter [Rattus
           norvegicus] >gi|3746793|gb|AAC64060.1| (AF081204) sodium
           dependent multivitamin transporter [Rattus norvegicus]
           >gi|3746795|gb|AAC64061.1| (AF081205) sodium dependent
           multivitamin transporter [Rattus norvegicus]
           Length = 634
           
 Score = 86.2 bits (210), Expect = 8e-16
 Identities = 109/471 (23%), Positives = 195/471 (41%), Gaps = 47/471 (9%)

Query: 7   ILAVLVFYLGFLIS--VGIY---QGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCL 61
           ++  +VF L  ++S  +G+Y   +G    +  +  +A R++     ALS  AT +SA  +
Sbjct: 25  VVDYVVFGLLLVLSLVIGLYHACRGWGRHTVGELLMADRKMGCLPVALSLLATFQSAVAI 84

Query: 62  LGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAE 121
           LG P   +  G    +      LG+++   +F     +        +  +Y+  R  +A 
Sbjct: 85  LGGPAEIYRFGTQYWFLGCSYFLGLLIPAHIFIPVFYR----LHLTSAYEYLELRFNKA- 139

Query: 122 KWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKS 181
             +RI G+ T  F    Y+G         LN + G D  L +L   +V   YT +GGLK+
Sbjct: 140 --VRICGTVTFIFQMVVYMGVALYAPSLALNAVTGFDLWLSVLALGIVCNIYTALGGLKA 197

Query: 182 VAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAA 241
           V +TD  Q ++M L  +V  IVG   +     ++A +    L  +G++            
Sbjct: 198 VIWTDVFQTLIMFLGQLVVIIVGAAKVGGLGHVWAVASQHGLI-SGIELD---------- 246

Query: 242 AIVFVIAEFSWFFGYLGGMPQLSI---------RFMAIKDDKNAKLARNIGIGWTIIAYI 292
              FV   F W   + G    LS+         R+++   +K A L+         +A  
Sbjct: 247 PDPFVRHTF-WTLAFGGVFMMLSLYGVNQAQVQRYLSSHSEKAAVLSCYAVFPCQQVALC 305

Query: 293 GALMIGWIGIAIFGPNGLK-DPEQVMPSVMLKLF-------PPALAAVFITGAVAAMLST 344
            + +IG +  A +    +    EQ  P  ++  F        P L  +F+    +  LST
Sbjct: 306 MSCLIGLVMFAYYKKYSMSPQQEQAAPDQLVLYFVMDLLKDMPGLPGLFVACLFSGSLST 365

Query: 345 ADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHL--I 402
             S     +T   E++++P+    +    +++M+SR    + G++ L MAY V SHL  +
Sbjct: 366 ISSAFNSLATVTMEDLIQPWF--PQLTETRAIMLSRSLAFAYGLVCLGMAY-VSSHLGSV 422

Query: 403 YTIVGYTWAGIGDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453
                  +  +G     +  L +F+   +       ++ GL    FWI  G
Sbjct: 423 LQAALSIFGMVGGPLLGLFCLGMFFPCANPLGAIVGLLTGLTM-AFWIGIG 472


>pir||S68513 thyroid iodide transport protein - rat >gi|1399954|gb|AAB03338.1|
           (U60282) thyroid sodium/iodide symporter NIS [Rattus
           norvegicus]
           Length = 618
           
 Score = 85.8 bits (209), Expect = 1e-15
 Identities = 96/404 (23%), Positives = 164/404 (39%), Gaps = 43/404 (10%)

Query: 10  VLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGFAF 69
           +L+   G  + VG+ +G + +S  DF   GRQL      LS  A+  SA  +LG+P  A 
Sbjct: 23  MLLVSTGIGLWVGLARGGQ-RSADDFFTGGRQLAAVPVGLSLAASFMSAVQVLGVPAEAA 81

Query: 70  AAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRILGS 129
             GL  +W   G +L  ++   +F     +        +   Y+  R   A   +R+ G+
Sbjct: 82  RYGLKFLWMCAGQLLNSLLTAFLFLPIFYR----LGLTSTYQYLELRFSRA---VRLCGT 134

Query: 130 ATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTDTVQ 189
                    Y G        +LN + GLD    +L T ++   YT +GG+K+V +TD  Q
Sbjct: 135 LQYLVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTLYTTVGGMKAVVWTDVFQ 194

Query: 190 AIVMILTLIVAPIVGVIYIA----------NHPELYATSVTAALSKAGVKYSTILGGMAG 239
            +VM++   V    GVI +           NH  +               ++ I+GG   
Sbjct: 195 VVVMLVGFWVILARGVILLGGPRNVLSLAQNHSRINLMDFDPDPRSRYTFWTFIVGG--- 251

Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSI-RFMAIKDDKNAKLARNIGIGWTIIAYIGALMIG 298
                       W   Y  G+ Q  + R++A   +  AKLA  +      +    A   G
Sbjct: 252 ---------TLVWLSMY--GVNQAQVQRYVACHTEGKAKLALLVNQLGLFLIVASAACCG 300

Query: 299 WIGIAIFG------PNGLKDPEQVMPSVMLKLFP--PALAAVFITGAVAAMLSTADSLLI 350
            +    +          +  P+Q MP ++L +F   P +  +F+  A +  LSTA + + 
Sbjct: 301 IVMFVYYKDCDPLLTGRISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSIN 360

Query: 351 LSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMA 394
             +    E+++KP +      PRK + +S+  +   G   L +A
Sbjct: 361 AMAAVTVEDLIKPRM--PGLAPRKLVFISKGLSFIYGSACLTVA 402


>gb|AAD37480.1|AF080067_1 (AF080067) sodium-dependent multi-vitamin transporter [Oryctolagus
           cuniculus]
           Length = 636
           
 Score = 84.7 bits (206), Expect = 2e-15
 Identities = 115/472 (24%), Positives = 189/472 (39%), Gaps = 57/472 (12%)

Query: 10  VLVFYLGFLISVGIY---QGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPG 66
           V    L F +++G+Y   +G    +     +A R++     ALS  AT +SA  +LG+P 
Sbjct: 31  VFSLLLVFSLAIGLYHACRGWGKHTVGQLLLADRRMGCLPVALSLLATFQSAVAILGVPS 90

Query: 67  FAFAAGLAAIWPAIGCV--LGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWI 124
             +  G    W  +GC   LG+++   VF     +        +  +Y+  R     K +
Sbjct: 91  EIYRFG-TQYW-FLGCCYFLGLLIPAHVFIPVFYR----LHLTSAYEYLELRF---NKVV 141

Query: 125 RILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAY 184
           RI G+ T  F    Y+G         LN + G D  L +L   +V   YT +GGLK+V +
Sbjct: 142 RICGTVTFIFQMVIYMGVVLYAPSLALNAVTGFDLWLSVLTLGIVCTIYTALGGLKAVIW 201

Query: 185 TDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAAIV 244
           TD  Q +VM L  +   IVG   +     ++  +    L  +G++               
Sbjct: 202 TDVFQTLVMFLGQLAVIIVGSAKVGGLGRVWDVASQHGLI-SGIELD----------PDP 250

Query: 245 FVIAEFSWFFGYLGGMPQLSI---------RFMAIKDDKNAKLARNIGIGWTIIAYIGAL 295
           FV   F W   + G    LS+         R+++ + +K A L+         +A     
Sbjct: 251 FVRHTF-WTLAFGGVFMMLSLYGVNQAQVQRYLSSRTEKAAVLSCYAVFPCQQVALSMGC 309

Query: 296 MIGWIGIAIFGPNGLKDPEQVMPSVMLKLF--------PPALAAVFITGAVAAMLSTADS 347
           +IG +  A +    +   +    S    L+         P L  +F+    +  LST  S
Sbjct: 310 LIGLVMFAYYQEYPMSTQQSQAASDQFVLYFVMDLLKGLPGLPGLFVACLFSGSLSTISS 369

Query: 348 LLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVG 407
                +T   E++++P+    E    +++M+SR      G++ L MAY      I + +G
Sbjct: 370 AFNSLATVTMEDLIRPWF--PECSEAQAIMLSRSLAFGYGLLCLGMAY------ISSQMG 421

Query: 408 YTWAGIGDTFSVI--VILTLF-WKRFHGKAVPPTIIAGL---LFTVFWISSG 453
                    F ++   +L LF    F   A PP  I GL   L   FWI  G
Sbjct: 422 PVLQAAISIFGMVGGPLLGLFCLGMFFPCANPPGAIVGLLAGLIMAFWIGIG 473


>pir||T35201 probable transmembrane transport - Streptomyces coelicolor
           >gi|3036892|emb|CAA18525.1| (AL022374) SC5B8.17,
           probable transmembrane transport protein, len: 530 aa;
           member of the sodium:solute symporter family, similar to
           many e.g. YJCG_ECOLI P32705 hypothetical protein , (549
           aa), fasta scores; opt: 935 z-score: 1534.8 E(): 0,
           43.6% ident>
           Length = 530
           
 Score = 83.9 bits (204), Expect = 4e-15
 Identities = 96/464 (20%), Positives = 197/464 (41%), Gaps = 33/464 (7%)

Query: 6   QILAVLVFYLGFLISVGI--YQGRKAK-SHKDFSIAGRQLPGWVAALSERATGESAWCLL 62
           Q LA+L+F     +++GI  + GR+ + S ++F   GR         +      SA   L
Sbjct: 6   QTLALLLFSTFVAVTLGITTWVGRRRQGSAEEFYAGGRLFSPMENGFAISGDYMSAASFL 65

Query: 63  GLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEK 122
           G+ G     G   +  ++G     +VAW V    + +        T  D +A R    E+
Sbjct: 66  GISGLIALNGYDGMLYSVG----FLVAWLVVLFLVAELVRNCGRFTLADVVAARM--RER 119

Query: 123 WIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITAL----VILPYTVMGG 178
            +RI    +       Y+ AQ +G G ++  L G   +     T +    +++ Y  +GG
Sbjct: 120 PVRIAAGTSSVTVSVLYLVAQMVGAGSLVALLLGGTSEAARTWTVIGVGALMVIYVSLGG 179

Query: 179 LKSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMA 238
           +++  +   V+A++++   +   +  ++ +  H ++     TAA  ++G   + +  G+A
Sbjct: 180 MRATTWIQIVKAVLLLGGTVA--LTALVLVRFHGDVDRLLRTAA-ERSGHGEAFLAPGLA 236

Query: 239 ----GAAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGA 294
                 A   F+    +   G   G+P +  RF  +   + A+ +    IG     Y+  
Sbjct: 237 YGGDWVARFDFISLGLALVLG-TAGLPHILSRFYTVPTARAARRSVVWSIGLIGGFYLMT 295

Query: 295 LMIGWIGIAIFGPNGLKDPEQV----MPSVMLKLFPPA-------LAAVFITGAVAAMLS 343
           +++G+   A+ GPN ++         +P + L L   A       L AV    A A +L+
Sbjct: 296 IVLGFGAAALVGPNAVRASNAAGNTAVPLLALDLGGGAHSTGGTVLFAVVAAVAFATILA 355

Query: 344 TADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIY 403
               + + SS   + ++    + +  + PR  + V+R+  V +G +A+ +  +     + 
Sbjct: 356 VVAGITLASSASVAHDLYAS-LRRRHSKPRSEVAVARVAAVGIGAVAIGLGLLARDLNVA 414

Query: 404 TIVGYTWAGIGDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTV 447
            +VG  +A        +++ +LFW+ F  +     +  GL+ +V
Sbjct: 415 FLVGLAFAVAASANLPVLLYSLFWRGFTTRGAVWAVYGGLVPSV 458


>pir||D72694 hypothetical protein APE0972 - Aeropyrum pernix (strain K1)
           >gi|5104641|dbj|BAA79956.1| (AP000060) 460aa long
           hypothetical protein [Aeropyrum pernix]
           Length = 460
           
 Score = 83.5 bits (203), Expect = 5e-15
 Identities = 85/349 (24%), Positives = 167/349 (47%), Gaps = 38/349 (10%)

Query: 29  AKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGFAFAAGLAAIWPAIGCVLGIIV 88
           A+   +F +AGR+L G+++A++  AT  S++ ++GL G A+  G+ ++   +  ++  ++
Sbjct: 2   ARGEGEFYLAGRRLTGFLSAMTYAATTYSSFMIVGLVGLAYFTGIGSLVFELAYLVATVI 61

Query: 89  AWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRILGSATIAFFFFFYVGAQYLGGG 148
             ++F+ R+ + + +   V+  + +A        W+ +  S         Y  AQ  G  
Sbjct: 62  LLSLFSRRVWRMSRERGWVSPGEMLADL--LGSPWVALTASLVFLVSLVPYASAQLKGIA 119

Query: 149 KVLNTLFGLDP------KLGMLITALVILPYTVMGGLKSVAYTDTVQAIVMILTLIVAPI 202
           + +  + G  P       + + +  L++L ++++ G++ V  TD  Q     L ++ A  
Sbjct: 120 ETIVAIAGYSPGDNTAYMVAVGVALLILLAWSLLAGVRGVVLTDAFQG----LWMLTAGS 175

Query: 203 VGVIYIANH--PELYATSVTAALSKAGVKYSTILGGMAGAAAIVFVIAEFSWFFGYLGGM 260
           +  +++A+    +  A+ V +A+  AG      L  M  A  ++  +    W F +    
Sbjct: 176 LLFLWLASRVFSKSGASEVLSAMESAG------LFDMWSATLLIGFVT--PWVF-FAVTN 226

Query: 261 PQLSIRFMAIKDDKNAKLARNI------GIGWTI-IAYIGALMIGWI--GIAIFGPNGLK 311
           PQ+  R    KD+++  L R I      G+ +T+ +  IG L    +  GI    P G  
Sbjct: 227 PQVVQRLYMPKDEES--LRRMILYFFLFGLYYTVLVVAIGFLARAGVELGILSIEPQG-- 282

Query: 312 DPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSENI 360
             +QV P  +L L  P LAA+  T  VAA +STADS+++  ++  S +I
Sbjct: 283 -RDQVTPQ-LLSLAHPLLAALVFTSIVAASVSTADSIILALASSASRDI 329


>dbj|BAB05941.1| (AP001514) Na+/myo-inositol cotransporter [Bacillus halodurans]
           Length = 580
           
 Score = 81.9 bits (199), Expect = 1e-14
 Identities = 109/498 (21%), Positives = 209/498 (41%), Gaps = 36/498 (7%)

Query: 7   ILAVLVFYLGFLISVGIYQ--GRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGL 64
           ILA  + Y  F++    Y+  G    S   + + GR L G V A S   T  S   ++GL
Sbjct: 5   ILASFLMYSIFVMWFSWYKTRGTDLSSSDGYFLGGRSLTGIVIASSLILTNLSTEQVVGL 64

Query: 65  PGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWI 124
            G AF   +  +   +   + +I+   VF  R  K        T  D++ +R     + I
Sbjct: 65  NGQAFGESMVVMAWEVTAPIALILMAFVFLPRYLK----LGITTIPDFLEQRFDLRTRQI 120

Query: 125 R----ILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVI----LPYTVM 176
                +LG AT+      Y GA  +     L+++  + P + +L  ++ I      Y ++
Sbjct: 121 VSVLFLLGYATVFLPTVLYSGALVIDSIFSLSSVMDISPFMIVLCISIAIGIISCGYVIL 180

Query: 177 GGLKSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGG 236
           GGLK+ A +DT+  I +I+  ++ PI+ +  +      +A+ V   +S    K + I   
Sbjct: 181 GGLKACAMSDTINGIGLIIGGLLIPILALFVLGRGD--FASGVGELVSANPTKLNAIGND 238

Query: 237 MAGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALM 296
            A     V +         Y      +  R +A K+    +        + I      ++
Sbjct: 239 QASVPWAVLLTGLLFNNLFYWCTNQSIIQRTLAAKNLAEGQKGVLFAGMFKIFGAAFLVL 298

Query: 297 IGWIGIAIFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEF 356
            G I   ++G + L + +   PS+++ + P AL+         A+LS+ +++L  S T F
Sbjct: 299 PGIIAYLLYG-DVLANADMAYPSLVIDVMPVALSGFLAAVLFGAILSSFNNVLNSSITLF 357

Query: 357 SENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVV---PSHLIYTIVGYTWAGI 413
           + +I KP I+K  A   + +   R+    L I A+++A  +   P  L Y +      G 
Sbjct: 358 TLDIYKP-IFKPNAKEPELVKAGRIFAACLAITAVVIAPFILYAPQGLYYFL--QEMNGF 414

Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSGLDAKVSVRLMNFIVTF---- 469
                + +++  F+ ++   + P  ++A  +  V +  S    KV +  +NF+       
Sbjct: 415 YSLPIIAMVIVGFFSKYVPASAPKVLVA--VHVVLYAGS----KVVLGEVNFLYVLSVLF 468

Query: 470 ---IVAIIATYAIKPEKT 484
              ++ ++    +KP +T
Sbjct: 469 PINVLVMLIVGRLKPRET 486


>sp|P23723|PUTP_KLEPN SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE)
           >gi|443996|emb|CAA52889.1| (X74934) proline permease
           [Klebsiella pneumoniae]
           Length = 160
           
 Score = 80.8 bits (196), Expect = 3e-14
 Identities = 43/117 (36%), Positives = 62/117 (52%), Gaps = 1/117 (0%)

Query: 1   MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60
           M   T +L   + Y+  ++ +G    R  K+  D+ + GR L  +V ALS  A+  S W 
Sbjct: 1   MAISTPMLVTFIVYIFGMVLIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60

Query: 61  LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKR 116
           L+GLPG  F +G++  W AIG  LG  + W + AGRLR   E   +A+T  DY   R
Sbjct: 61  LMGLPGAIFISGISESWIAIGLTLGAWINWKLVAGRLRVHTEVNNNALTXPDYFTGR 117


>emb|CAC16517.1| (AL450223) putative integral membrane transport protein
           [Streptomyces coelicolor]
           Length = 523
           
 Score = 80.0 bits (194), Expect = 6e-14
 Identities = 88/429 (20%), Positives = 184/429 (42%), Gaps = 30/429 (6%)

Query: 8   LAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGF 67
           L V+V YL  +  +G+ +  + KS KD+ +    +P W  + S  AT  S   ++ +PG 
Sbjct: 6   LVVIVVYLIGIAWIGLRKAGRQKSAKDYFVGEGHMPWWTVSFSVVATETSVLTVISVPGG 65

Query: 68  AFAA-GLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRI 126
           A++  G   +  A+G V+G +V   V     ++       V+   Y+  R       +++
Sbjct: 66  AYSGQGFGNVELALGYVVGRVVVATVLIPLYKRGG----FVSAYQYLGDRF-----GLKL 116

Query: 127 LGSATIAFFF--FFYVGAQYLGGG---KVLNTLFGLDP--KLGMLITALVILPYTVMGGL 179
            G A++ F F      G +        K+L   FG+    +  +++  L+ + YT +GG+
Sbjct: 117 QGLASVTFVFTRLLAEGVRLFASAIPIKLLLDEFGVHASYRAIIIVITLITVVYTYLGGI 176

Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239
           K+V +TD +Q ++ +   ++A  V   ++    + YA ++ A   +       +   +  
Sbjct: 177 KAVIWTDAIQMVLYLGGAVLAVAVLSAHVGG--DGYARALDAGKFQLFDTDFNLAHILTS 234

Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFM----AIKDDKNAKLARNIGIGWTIIAY--IG 293
             A+   I   + F     G  QL ++ +     +++ + A +A  + +     A+  +G
Sbjct: 235 PFALPTAIIGGAIFAMASHGSDQLIVQRVLATRTLREGQKAMIASGVFVTVQFAAFSLVG 294

Query: 294 ALMIGWIGIAIFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353
           AL+  +     F   GL   + + P  +L   P  ++ + + G + A + +  S L   S
Sbjct: 295 ALLWSYNEGRSFAELGLSSSDNLYPEFILHGLPVVVSGLLVAGILGAAMGSLSSALNSMS 354

Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALI-MAYVVPSHLIY----TIVGY 408
                +I+  +     ++     +   +T V   ++A+   A+   +  +Y    TI GY
Sbjct: 355 NSTVADIIHSFFRSTPSEEALLRLARWMTLVWATLMAVFACAFSASTGNVYLTGLTIAGY 414

Query: 409 TWAGIGDTF 417
           T+  +   F
Sbjct: 415 TYGALLGAF 423


>pir||S52839 dhlC protein - Xanthobacter autotrophicus
           >gi|763398|emb|CAA60038.1| (X86084) dhlC [Xanthobacter
           autotrophicus]
           Length = 516
           
 Score = 78.8 bits (191), Expect = 1e-13
 Identities = 97/454 (21%), Positives = 185/454 (40%), Gaps = 29/454 (6%)

Query: 8   LAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGF 67
           LA+ V  L   +++  +  R+ ++  DF  A   L       +      SA   LG  G 
Sbjct: 6   LAIFVAILALTLAITWWAARRTRTASDFYTADGTLGPIQNGFALAGDWMSAAAFLGFSGL 65

Query: 68  AFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKR--HPEAEKWIR 125
           A   G+     A G ++  +    + A  +R         T  D IA R   P+A +   
Sbjct: 66  AALYGMDGSLYAAGALVAFLAILMLVAEPIRNTGR----FTLGDVIAFRMQRPQA-RLAA 120

Query: 126 ILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYT 185
           +LG+  ++     Y+  Q  GG  ++  L G+   + +++  L +L Y V GG+ +  + 
Sbjct: 121 VLGTVVVSLA---YLVPQMAGGAALIKLLLGVPYAISIVVVGLGMLVYVVFGGMIATTWV 177

Query: 186 DTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKA-GVKYSTILGGMAGAAAIV 244
             ++A++    L+ A  V V  +  H      SV AA     G K   +  G      + 
Sbjct: 178 QIIKAVM----LLSAAAVLVALLLAHFGFDPFSVFAAAEDTYGAK--ILAPGNYLKHPLD 231

Query: 245 FVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAK--------LARNIGIGWTIIAYIGALM 296
            +    S+ FG   G+P +  RF  + D + A+        LA +  +  T+I    A++
Sbjct: 232 QLSLGLSFAFG-TAGLPHVMTRFYTVPDAQTARRSAVWLMFLAGSFFLVTTLIGLGSAVL 290

Query: 297 IGWIGIAIFGPNG---LKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353
           +G   I      G   L    Q +      +      AV +  A A +L+   +L + +S
Sbjct: 291 VGQDAIRAADKGGNLALPLLAQHLGGGPDSIGGQVFLAVVVAVAFATILAVVAALTLSTS 350

Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413
              + ++    +       ++ + V+R++TV +   A++   +     +  +V    +  
Sbjct: 351 GAIAHDLYVNVLRGGHVSEQEQVKVARISTVIVSAFAILFGLLAQGINVAVLVILAISVA 410

Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTV 447
                 +++L+LFW+RF+   V   ++AGL+  V
Sbjct: 411 ASANFPVIVLSLFWQRFNTAGVVTGMVAGLVSAV 444


>gb|AAF17249.1|AF208031_1 (AF208031) SGLT1 protein [Mus musculus]
           Length = 665
           
 Score = 76.9 bits (186), Expect = 5e-13
 Identities = 102/485 (21%), Positives = 202/485 (41%), Gaps = 61/485 (12%)

Query: 8   LAVLVFYLGFLISVGIYQ--GRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLP 65
           ++V+V Y   +++VG++        +   F +AGR +  W    S  A+   +   +GL 
Sbjct: 29  ISVIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGLA 88

Query: 66  GFAFAAGLAA---IWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEK 122
           G   AAG+A     W A+  VL +++ W      +     K   VT  +Y+ KR     K
Sbjct: 89  GTGAAAGIAMGGFEWNAL--VLVVVLGWIFVPIYI-----KAGVVTMPEYLRKRF--GGK 139

Query: 123 WIRI-LGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKS 181
            I+I L   ++  + F  + A    G   +N   GLD  L + I   +   YT+ GGL +
Sbjct: 140 RIQIYLSVLSLLLYIFTKISADIFSGAIFINLALGLDIYLAIFILLAITALYTITGGLAA 199

Query: 182 VAYTDTVQAIVMILTLIVAPIVGVIYIANHP---ELYATSVTAALSKAGVKYSTILGGMA 238
           V YTDT+Q  +M++   +        +  +    + Y  ++   +S              
Sbjct: 200 VIYTDTLQTAIMLVGSFILTGFAFNEVGGYEAFMDKYMKAIPTKVSNGNFTAKEECYTPR 259

Query: 239 GAAAIVF---VIAEFSWFFGYLGGMPQLSIRF-----MAIKDDKNAKLARNIGIGWTIIA 290
             +  +F   +  +  W  G + G+  L++ +     + ++   +AK   ++  G T+  
Sbjct: 260 ADSFHIFRDPITGDMPW-PGLIFGLAILALWYWCTDQVIVQRCLSAKNMSHVKAGCTLCG 318

Query: 291 YIGAL------MIGWIGIAIFGPN-GLKDPEQ--------------VMPSVMLKLFPPAL 329
           Y+  L      M G I   ++        PE+                P+++++L P  L
Sbjct: 319 YLKLLPMFLMVMPGMISRILYTEKIACVLPEECQKYCGTPVGCTNIAYPTLVVELMPNGL 378

Query: 330 AAVFITGAVAAMLSTADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGII 389
             + ++  +A+++S+  S+   +ST F+ +I      + +A  ++ ++  RL  + L  I
Sbjct: 379 RGLMLSVMMASLMSSLTSIFNSASTLFTMDIYTK--IRKKASEKELMIAGRLFILVLIGI 436

Query: 390 ALIMAYVVPS-------HLIYTIVGYTWAGIGDTFSVIVILTLFWKRFHGKAVPPTIIAG 442
           ++    +V S         I +I  Y    +G   + + +L +F KR + +     +I G
Sbjct: 437 SIAWVPIVQSAQSGQLFDYIQSITSY----LGPPIAAVFLLAIFCKRVNEQGAFWGLILG 492

Query: 443 LLFTV 447
            L  +
Sbjct: 493 FLIGI 497


>pir||S48857 glucose transport protein - sheep >gi|2148056|pir||S59638 glucose
           transport protein SGLT1, parotid gland - sheep
           Length = 664
           
 Score = 76.9 bits (186), Expect = 5e-13
 Identities = 109/528 (20%), Positives = 210/528 (39%), Gaps = 68/528 (12%)

Query: 8   LAVLVFYLGFLISVGIYQ--GRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLP 65
           ++V+V Y   +++VG++        +   F +AGR +  W    S  A+   +   +GL 
Sbjct: 29  ISVIVIYFVVVMAVGLWHMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGLA 88

Query: 66  GFAFAAGLAA---IWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEK 122
           G   AAG+A     W A+  +L +++ W      +     K   VT  +Y+ KR      
Sbjct: 89  GTGAAAGIATGGFEWNAL--ILVVLLGWVFVPIYI-----KAGVVTMPEYLRKRFGGQRI 141

Query: 123 WIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSV 182
            +  L   ++  + F  + A    G   +N   GLD  L + I   +   YT+ GGL +V
Sbjct: 142 QV-YLSVLSLVLYIFTKISADIFSGAIFINLALGLDLYLAIFILLAITALYTITGGLAAV 200

Query: 183 AYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAA 242
            YTDT+Q ++M+L   +        +  +       + A  +      +T+        A
Sbjct: 201 IYTDTLQTVIMLLGSFILTGFAFHEVGGYSAFVTKYMNAIPTVTSYGNTTVKKECYTPRA 260

Query: 243 IVFVI------AEFSWFFGYLGGMPQLSIRF-----MAIKDDKNAKLARNIGIGWTIIAY 291
             F I       +  W  G + G+  +S+ +     + ++   +AK   ++  G  +  Y
Sbjct: 261 DSFHIFRDPLKGDLPW-PGLIFGLTIISLWYWCTDQVIVQRCLSAKNMSHVKAGCIMCGY 319

Query: 292 IGAL------MIGWIGIAIFGPN-GLKDPEQ--------------VMPSVMLKLFPPALA 330
           +  L      M G I   +F        P +                P+++++L P  L 
Sbjct: 320 MKLLPMFLMVMPGMISRILFTEKVACTVPSECEKYCGTKVGCTNIAYPTLVVELMPNGLR 379

Query: 331 AVFITGAVAAMLSTADSLLILSSTEFSENILKPYIYKNEADPRKSLMVS----RLTTVSL 386
            + ++  +A+++S+  S+   +ST F+ +I   Y    +    K LM++     L  + +
Sbjct: 380 GLMLSVMLASLMSSLTSIFNSASTLFTMDI---YTKIRKKASEKELMIAGRLFMLVLIGV 436

Query: 387 GIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVIVILTLFWKR------FHGKAVPPTII 440
            I  + +     S  ++  +    + +G   + + +L +F KR      F G  +   I 
Sbjct: 437 SIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFCKRVNEPGAFWGLIIGFLIG 496

Query: 441 AGLLFTVFWISSGLDAKVS--------VRLMNF-IVTFIVAIIATYAI 479
              + T F   +G   + S        V  + F I+ F++ II   AI
Sbjct: 497 VSRMITEFAYGTGSCMEPSNCPTIICGVHYLYFAIILFVITIIVILAI 544


>sp|P53791|SL51_SHEEP SODIUM/GLUCOSE COTRANSPORTER 1 (NA(+)/GLUCOSE COTRANSPORTER 1)
           (HIGH AFFINITY SODIUM-GLUCOSE COTRANSPORTER)
           >gi|2119800|pir||S59637 glucose transport protein SGLT1,
           intestinal - sheep >gi|861071|emb|CAA57808.1| (X82410)
           sodium/glucose cotransporter [Ovis aries]
           >gi|861073|emb|CAA57809.1| (X82411) sodium/glucose
           cotransporter-like protein [Ovis aries]
           >gi|2326776|emb|CAA04483.1| (AJ001026) sodium/glucose
           symporter-like protein [Ovis aries]
           Length = 664
           
 Score = 76.5 bits (185), Expect = 6e-13
 Identities = 109/528 (20%), Positives = 210/528 (39%), Gaps = 68/528 (12%)

Query: 8   LAVLVFYLGFLISVGIYQ--GRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLP 65
           ++V+V Y   +++VG++        +   F +AGR +  W    S  A+   +   +GL 
Sbjct: 29  ISVIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGLA 88

Query: 66  GFAFAAGLAA---IWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEK 122
           G   AAG+A     W A+  +L +++ W      +     K   VT  +Y+ KR      
Sbjct: 89  GTGAAAGIATGGFEWNAL--ILVVLLGWVFVPIYI-----KAGVVTMPEYLRKRFGGQRI 141

Query: 123 WIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSV 182
            +  L   ++  + F  + A    G   +N   GLD  L + I   +   YT+ GGL +V
Sbjct: 142 QV-YLSVLSLVLYIFTKISADIFSGAIFINLALGLDLYLAIFILLAITALYTITGGLAAV 200

Query: 183 AYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAA 242
            YTDT+Q ++M+L   +        +  +       + A  +      +T+        A
Sbjct: 201 IYTDTLQTVIMLLGSFILTGFAFHEVGGYSAFVTKYMNAIPTVTSYGNTTVKKECYTPRA 260

Query: 243 IVFVI------AEFSWFFGYLGGMPQLSIRF-----MAIKDDKNAKLARNIGIGWTIIAY 291
             F I       +  W  G + G+  +S+ +     + ++   +AK   ++  G  +  Y
Sbjct: 261 DSFHIFRDPLKGDLPW-PGLIFGLTIISLWYWCTDQVIVQRCLSAKNMSHVKAGCIMCGY 319

Query: 292 IGAL------MIGWIGIAIFGPN-GLKDPEQ--------------VMPSVMLKLFPPALA 330
           +  L      M G I   +F        P +                P+++++L P  L 
Sbjct: 320 MKLLPMFLMVMPGMISRILFTEKVACTVPSECEKYCGTKVGCTNIAYPTLVVELMPNGLR 379

Query: 331 AVFITGAVAAMLSTADSLLILSSTEFSENILKPYIYKNEADPRKSLMVS----RLTTVSL 386
            + ++  +A+++S+  S+   +ST F+ +I   Y    +    K LM++     L  + +
Sbjct: 380 GLMLSVMLASLMSSLTSIFNSASTLFTMDI---YTKIRKKASEKELMIAGRLFMLVLIGV 436

Query: 387 GIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVIVILTLFWKR------FHGKAVPPTII 440
            I  + +     S  ++  +    + +G   + + +L +F KR      F G  +   I 
Sbjct: 437 SIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFCKRVNEPGAFWGLIIGFLIG 496

Query: 441 AGLLFTVFWISSGLDAKVS--------VRLMNF-IVTFIVAIIATYAI 479
              + T F   +G   + S        V  + F I+ F++ II   AI
Sbjct: 497 VSRMITEFAYGTGSCMEPSNCPTIICGVHYLYFAIILFVITIIVILAI 544


>sp|P31448|YIDK_ECOLI HYPOTHETICAL 62.1 KD PROTEIN IN EMRD-GLVG INTERGENIC REGION
           >gi|7430324|pir||H65169 probable transport protein yidK
           - Escherichia coli (strain K-12)
           >gi|290528|gb|AAA62031.1| (L10328) similar to glucose
           transport proteins [Escherichia coli]
           >gi|1790113|gb|AAC76702.1| (AE000445) putative
           cotransporter [Escherichia coli K12]
           Length = 571
           
 Score = 76.1 bits (184), Expect = 8e-13
 Identities = 114/510 (22%), Positives = 214/510 (41%), Gaps = 65/510 (12%)

Query: 11  LVFYLGFLISVGIYQGRKAK-----SHKDFSIAGRQLPGWVAALSERATGESAWCLLGLP 65
           ++ ++GF + V +    K +     S + + +AGR L   V A S   T  S   L+GL 
Sbjct: 6   ILSFVGFTLLVAVITWWKVRKTDTGSQQGYFLAGRSLKAPVIAASLMLTNLSTEQLVGLS 65

Query: 66  GFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIR 125
           G A+ +G++ +   +   + +I    +F  R  K        T  D++ +R+   +K  R
Sbjct: 66  GQAYKSGMSVMGWEVTSAVTLIFLALIFLPRYLKRG----IATIPDFLEERY---DKTTR 118

Query: 126 ILGSATIAFFFFFYVGAQYL-----GGGKVLNTLFGLDPKL----GMLITALVILP---- 172
           I+    I F F    G  +L      G   LN+LF +   L    G  I  LVIL     
Sbjct: 119 II----IDFCFLIATGVCFLPIVLYSGALALNSLFHVGESLQISHGAAIWLLVILLGLAG 174

Query: 173 --YTVMGGLKSVAYTDTVQAIVMILTLIVAPIVGVIYIANHP-----ELYATSVTAALSK 225
             Y V+GGL+++A  D++  I +++  ++ P+ G+I +         E   T     L+ 
Sbjct: 175 ILYAVIGGLRAMAVADSINGIGLVIGGLMVPVFGLIAMGKGSFMQGIEQLTTVHAEKLNS 234

Query: 226 AGVKYSTILGGMAGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIG 285
            G     +  G A    I  ++  F W      G+ Q ++   ++ + +   L       
Sbjct: 235 IGGPTDPLPIGAAFTGLI--LVNTFYWCTNQ--GIVQRTLASKSLAEGQKGALLT----- 285

Query: 286 WTIIAYIGALMIGWIGIAIFG-PNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLST 344
             ++  +  L++   G+  F     L   +   P+++  + P  +   F      A++ST
Sbjct: 286 -AVLKMLDPLVLVLPGLIAFHLYQDLPKADMAYPTLVNNVLPVPMVGFFGAVLFGAVIST 344

Query: 345 ADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVV---PSHL 401
            +  L  +ST FS  I +  I +N A+P++ + V R     + I+++++A  +   P  L
Sbjct: 345 FNGFLNSASTLFSMGIYRRIINQN-AEPQQLVTVGRKFGFFIAIVSVLVAPWIANAPQGL 403

Query: 402 IYTIVGYTWA----GIGDT-FSVIVILTLFWKRFHGKAVPPTIIAGLL--FTVFWISSGL 454
                 Y+W     GI +     I+I+  F+ R    A    +  G++   T+ ++    
Sbjct: 404 ------YSWMKQLNGIYNVPLVTIIIMGFFFPRIPALAAKVAMGIGIISYITINYLVKFD 457

Query: 455 DAKVSVRLMNFIVTFIVAIIATYAIKPEKT 484
              + V    F +  +V ++  + IKP  T
Sbjct: 458 FHFLYVLACTFCINVVVMLVIGF-IKPRAT 486


>pir||S48858 glucose transport protein homolog - sheep
           Length = 664
           
 Score = 75.7 bits (183), Expect = 1e-12
 Identities = 109/528 (20%), Positives = 209/528 (38%), Gaps = 68/528 (12%)

Query: 8   LAVLVFYLGFLISVGIYQ--GRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLP 65
           ++V+V Y   +++VG++        +   F +AGR +  W    S  A+   +   +GL 
Sbjct: 29  ISVIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGLA 88

Query: 66  GFAFAAGLAA---IWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEK 122
           G   AAG+A     W A+  +L +++ W      +     K   VT  +Y+ KR      
Sbjct: 89  GTGAAAGIATGGFEWNAL--ILVVLLGWVFVPIYI-----KAGVVTMPEYLRKRFGGQRI 141

Query: 123 WIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSV 182
            +  L   ++  + F  + A    G   +N   GLD  L + I   +   YT+ GGL +V
Sbjct: 142 QV-YLSVLSLVLYIFTKISADIFSGAIFINLALGLDLYLAIFILLAITALYTITGGLAAV 200

Query: 183 AYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAA 242
            YTDT+Q ++M+L   +        +  +       + A  +      +T+        A
Sbjct: 201 IYTDTLQTVIMLLGSFILTGFAFHEVGGYSAFVRKYMNAIPTVTSYGNTTVKKECYTPRA 260

Query: 243 IVFVI------AEFSWFFGYLGGMPQLSIRF-----MAIKDDKNAKLARNIGIGWTIIAY 291
             F I       +  W  G + G+  +S+ +     + ++   +AK   ++  G  +  Y
Sbjct: 261 DSFHIFRDPLKGDLPW-PGLIFGLTIISLWYWCTDQVIVQRCLSAKNMSHVKAGCIMCGY 319

Query: 292 IGAL------MIGWIGIAIFGPN-GLKDPEQ--------------VMPSVMLKLFPPALA 330
           +  L      M G I   +F        P +                P+++++L P  L 
Sbjct: 320 MKLLPMFLMVMPGMISRILFTEKVACTVPSECEKYCGTKVGCTNIAYPTLVVELMPNGLR 379

Query: 331 AVFITGAVAAMLSTADSLLILSSTEFSENILKPYIYKNEADPRKSLMVS----RLTTVSL 386
            + ++  +A+++S+  S+   +ST F+ +I   Y    +    K LM++     L  + +
Sbjct: 380 GLMLSVMLASLMSSLTSIFNSASTLFTMDI---YTKIRKKASEKELMIAGRLFMLVVIGV 436

Query: 387 GIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVIVILTLFWKR------FHGKAVPPTII 440
            I  + +     S  ++  +    + +G     + +L +F KR      F G  +   I 
Sbjct: 437 SIAWVPIVQSAQSGQLFDYIQSITSYLGPPMRAVFLLAIFCKRVNEPGAFWGLIIGFLIG 496

Query: 441 AGLLFTVFWISSGLDAKVS--------VRLMNF-IVTFIVAIIATYAI 479
              + T F   +G   + S        V  + F I+ F++ II   AI
Sbjct: 497 VSRMITEFAYGTGSCMEPSNCPTIICGVHYLYFAIILFVITIIVILAI 544


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.327    0.142    0.429 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 169975974
Number of Sequences: 2977
Number of extensions: 6928073
Number of successful extensions: 29246
Number of sequences better than 1.0e-10: 104
Number of HSP's better than  0.0 without gapping: 41
Number of HSP's successfully gapped in prelim test: 63
Number of HSP's that attempted gapping in prelim test: 28868
Number of HSP's gapped (non-prelim): 123
length of query: 484
length of database: 189,106,746
effective HSP length: 53
effective length of query: 431
effective length of database: 157,386,935
effective search space: 67833768985
effective search space used: 67833768985
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (21.7 bits)
S2: 167 (69.5 bits)