BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB0609 (putP-1) DE:OSMOREGULATED PROLINE TRANSPORTER (484 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||E75138 osmoregulated proline transporter PAB0609 - Pyrococc... 957 0.0 sp|O06493|OPUE_BACSU OSMOREGULATED PROLINE TRANSPORTER (SODIUM/P... 261 1e-68 emb|CAA70363.1| (Y09163) proline transport system [Corynebacteri... 261 1e-68 pir||C71008 probable proline permease - Pyrococcus horikoshii >g... 257 1e-67 pir||A75123 proline permease (putp-2) PAB1841 - Pyrococcus abyss... 255 1e-66 pir||H82382 sodium/proline symporter VCA1071 [imported] - Vibrio... 255 1e-66 pir||T44298 proline transporter [imported] - Bacillus halodurans... 252 6e-66 pir||D75188 proline symporter (proline permease). PAB2354 - Pyro... 248 1e-64 pir||B69759 sodium/proline symporter ycgO - Bacillus subtilis >g... 238 8e-62 gb|AAA79365.1| (U06451) proline permease homolog [Staphylococcus... 234 2e-60 pir||T48676 proline uptake protein [validated] - Staphylococcus ... 231 2e-59 pir||B81297 sodium/proline symporter Cj1502c [imported] - Campyl... 229 7e-59 pir||G81202 sodium/proline symporter NMB0402 [imported] - Neisse... 228 9e-59 pir||JC2382 sodium/proline symporter - Pseudomonas fluorescens >... 228 1e-58 pir||F83547 sodium/proline symporter PutP PA0783 [imported] - Ps... 227 2e-58 pir||A71980 sodium/proline symporter - Helicobacter pylori (stra... 226 4e-58 pir||G64526 sodium/proline symporter - Helicobacter pylori (stra... 224 1e-57 pir||S10220 sodium/proline symporter - Salmonella typhimurium 224 2e-57 gb|AAA24461.1| (L01132) proline permease [Escherichia coli] >gi|... 223 4e-57 sp|P07117|PUTP_ECOLI SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE)... 222 5e-57 sp|P10502|PUTP_SALTY SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE)... 222 5e-57 gb|AAA99288.1| (L01146) proline permease [Salmonella sp.] >gi|15... 222 5e-57 gb|AAA24463.1| (L01150) proline permease [Escherichia coli] >gi|... 222 5e-57 gb|AAA27199.1| (L01135) proline permease [Salmonella typhimurium] 222 5e-57 gb|AAA26389.1| (L01134) proline permease [Rickettsia typhi] 222 5e-57 gb|AAA99282.1| (L01140) proline permease [Salmonella sp.] >gi|15... 222 5e-57 gb|AAA24466.1| (L01153) proline permease [Escherichia coli] >gi|... 222 5e-57 gb|AAA24462.1| (L01133) proline permease [Escherichia coli] 222 7e-57 gb|AAA24468.1| (L01155) proline permease [Escherichia coli] 222 7e-57 gb|AAA99290.1| (L01148) proline permease [Salmonella sp.] 222 9e-57 gb|AAA99291.1| (L01149) proline permease [Salmonella sp.] 222 9e-57 gb|AAA99278.1| (L01136) proline permease [Salmonella sp.] 221 1e-56 gb|AAA99279.1| (L01137) proline permease [Salmonella sp.] 221 1e-56 gb|AAA24465.1| (L01152) proline permease [Escherichia coli] 221 2e-56 gb|AAA99281.1| (L01139) proline permease [Salmonella sp.] 221 2e-56 gb|AAA99280.1| (L01138) proline permease [Salmonella sp.] 220 2e-56 gb|AAA99284.1| (L01142) proline permease [Salmonella sp.] >gi|15... 220 2e-56 gb|AAA99286.1| (L01144) proline permease [Salmonella sp.] >gi|15... 220 2e-56 gb|AAF25001.1|AF153207_2 (AF153207) proline permease [Pseudomona... 215 7e-55 gb|AAG19342.1| (AE005029) proline permease; PutP [Halobacterium ... 210 2e-53 dbj|BAB06425.1| (AP001516) proline transporter [Bacillus halodur... 208 9e-53 sp|P45174|PUTP_HAEIN SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE)... 207 2e-52 gi|11498674 pantothenate permease (panF-1) [Archaeoglobus fulgid... 170 4e-41 sp|P44963|PANF_HAEIN SODIUM/PANTOTHENATE SYMPORTER (PANTOTHENATE... 152 1e-35 pir||D65118 pantothenate permease [validated] - Escherichia coli... 144 2e-33 sp|P16256|PANF_ECOLI SODIUM/PANTOTHENATE SYMPORTER (PANTOTHENATE... 143 4e-33 pir||C69115 sodium/proline symporter (proline permease) - Methan... 137 3e-31 gb|AAF45280.1| (AF230619) proline permease [Escherichia coli] 135 1e-30 gb|AAF45283.1| (AF230622) proline permease [Escherichia coli] 132 6e-30 gb|AAF45263.1| (AF230602) proline permease [Escherichia coli] >g... 132 8e-30 gb|AAF45264.1| (AF230603) proline permease [Escherichia coli] >g... 132 8e-30 gb|AAF45285.1| (AF230624) proline permease [Escherichia coli] 132 8e-30 gb|AAF45286.1| (AF230625) proline permease [Escherichia coli] 130 4e-29 pir||E70201 pantothenate permease (panF) homolog - Lyme disease ... 127 2e-28 sp|P39599|YWCA_BACSU HYPOTHETICAL 55.0 KD PROTEIN IN EPR-GALK IN... 120 3e-26 pir||JU0296 pantothenate permease - Escherichia coli >gi|147067|... 118 2e-25 pir||F83241 probable sodium:solute symporter PA3234 [imported] -... 117 2e-25 emb|CAB59438.1| (AL132644) putative transmembrane transport prot... 117 3e-25 sp|P32705|YJCG_ECOLI HYPOTHETICAL 59.2 KD PROTEIN IN SOXR-ACS IN... 111 2e-23 dbj|BAB07462.1| (AP001519) Na+/solute symporter (Ssf family) [Ba... 109 5e-23 gi|11498574 proline permease (putP-2) [Archaeoglobus fulgidus] >... 105 1e-21 pir||C82582 Na+-dependent symport homolog XF2251 [imported] - Xy... 104 2e-21 pir||H75513 probable sodium/proline symporter DR0477 [similarity... 102 9e-21 gi|11497853 pantothenate permease (panF-3) [Archaeoglobus fulgid... 102 1e-20 gi|11497636 proline permease (putP-1) [Archaeoglobus fulgidus] >... 101 2e-20 pir||G83610 probable sodium:solute symporter PA0287 [imported] -... 101 2e-20 emb|CAA94864.1| (Z71176) phenylacetic acid permease [Pseudomonas... 101 3e-20 pir||E83468 probable sodium:solute symport protein PA1418 [impor... 101 3e-20 pir||S75887 hypothetical protein - Synechocystis sp. (strain PCC... 100 3e-20 pir||H71097 hypothetical protein PH1044 - Pyrococcus horikoshii ... 99 1e-19 gi|11498821 proline permease (putP-3) [Archaeoglobus fulgidus] >... 98 2e-19 gb|AAG20007.1| (AE005081) pantothenate permease; PanF [Halobacte... 98 2e-19 pir||T03475 transmembrane protein - Rhodobacter capsulatus >gi|3... 97 4e-19 gi|4507035 solute carrier family 5 (sodium iodide symporter), me... 96 7e-19 gi|11498804 pantothenate permease (panF-2) [Archaeoglobus fulgid... 96 9e-19 dbj|BAA24835.1| (D87920) sodium iodide symporter [Homo sapiens] 96 9e-19 emb|CAB88444.1| (AL353815) putative sodium-coupled permease [Str... 95 2e-18 emb|CAC17810.1| (AJ276242) sodium iodide symporter [Sus scrofa] 95 2e-18 emb|CAC17816.1| (AJ276292) sodium iodide symporter [Sus scrofa] 95 2e-18 gi|11141885 solute carrier family 5 (choline transporter), membe... 92 1e-17 sp|P96169|SGLT_VIBPA SODIUM/GLUCOSE COTRANSPORTER (NA(+)/GLUCOSE... 92 1e-17 dbj|BAA11215.1| (D78137) Na+/glucose symporter [Vibrio parahaemo... 92 2e-17 gi|11528510 solute carrier family 5 (choline transporter), membe... 92 2e-17 gb|AAG36945.1| (AF276872) sodium and chloride-dependent high-aff... 91 2e-17 dbj|BAA90483.1| (AB030946) high-affinity choline transporter CHO... 91 3e-17 dbj|BAA90484.1| (AB030947) high-affinity choline transporter CHT... 90 4e-17 emb|CAB95932.1| (AL359989) putative sodium:solute symporter [Str... 88 3e-16 prf||2204393A Na/I symporter [Rattus norvegicus] 87 6e-16 gi|10863879 solute carrier family 5 (sodium-dependent vitamin tr... 87 6e-16 gi|11429441 solute carrier family 5 (sodium-dependent vitamin tr... 87 6e-16 gb|AAC12270.1| (AF026554) sodium-dependent multi-vitamin transpo... 86 8e-16 pir||S68513 thyroid iodide transport protein - rat >gi|1399954|g... 86 1e-15 gb|AAD37480.1|AF080067_1 (AF080067) sodium-dependent multi-vitam... 85 2e-15 pir||T35201 probable transmembrane transport - Streptomyces coel... 84 4e-15 pir||D72694 hypothetical protein APE0972 - Aeropyrum pernix (str... 83 5e-15 dbj|BAB05941.1| (AP001514) Na+/myo-inositol cotransporter [Bacil... 82 1e-14 sp|P23723|PUTP_KLEPN SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE)... 81 3e-14 emb|CAC16517.1| (AL450223) putative integral membrane transport ... 80 6e-14 pir||S52839 dhlC protein - Xanthobacter autotrophicus >gi|763398... 79 1e-13 gb|AAF17249.1|AF208031_1 (AF208031) SGLT1 protein [Mus musculus] 77 5e-13 pir||S48857 glucose transport protein - sheep >gi|2148056|pir||S... 77 5e-13 sp|P53791|SL51_SHEEP SODIUM/GLUCOSE COTRANSPORTER 1 (NA(+)/GLUCO... 76 6e-13 sp|P31448|YIDK_ECOLI HYPOTHETICAL 62.1 KD PROTEIN IN EMRD-GLVG I... 76 8e-13 pir||S48858 glucose transport protein homolog - sheep 76 1e-12 >pir||E75138 osmoregulated proline transporter PAB0609 - Pyrococcus abyssi (strain Orsay) >gi|5458333|emb|CAB49822.1| (AJ248285) OSMOREGULATED PROLINE TRANSPORTER [Pyrococcus abyssi] Length = 484 Score = 957 bits (2448), Expect = 0.0 Identities = 484/484 (100%), Positives = 484/484 (100%) Query: 1 MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60 MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC Sbjct: 1 MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60 Query: 61 LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEA 120 LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEA Sbjct: 61 LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEA 120 Query: 121 EKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLK 180 EKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLK Sbjct: 121 EKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLK 180 Query: 181 SVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGA 240 SVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGA Sbjct: 181 SVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGA 240 Query: 241 AAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGWI 300 AAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGWI Sbjct: 241 AAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGWI 300 Query: 301 GIAIFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSENI 360 GIAIFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSENI Sbjct: 301 GIAIFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSENI 360 Query: 361 LKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVI 420 LKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVI Sbjct: 361 LKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVI 420 Query: 421 VILTLFWKRFHGKAVPPTIIAGLLFTVFWISSGLDAKVSVRLMNFIVTFIVAIIATYAIK 480 VILTLFWKRFHGKAVPPTIIAGLLFTVFWISSGLDAKVSVRLMNFIVTFIVAIIATYAIK Sbjct: 421 VILTLFWKRFHGKAVPPTIIAGLLFTVFWISSGLDAKVSVRLMNFIVTFIVAIIATYAIK 480 Query: 481 PEKT 484 PEKT Sbjct: 481 PEKT 484 >sp|O06493|OPUE_BACSU OSMOREGULATED PROLINE TRANSPORTER (SODIUM/PROLINE SYMPORTER) >gi|7442757|pir||H69670 sodium/proline symporter opuE - Bacillus subtilis >gi|2114423|gb|AAB66512.1| (U92466) osmoregulated proline transporter [Bacillus subtilis] >gi|2465556|gb|AAB72182.1| (AF011545) OpuE [Bacillus subtilis] >gi|2632980|emb|CAB12486.1| (Z99107) proline transporter [Bacillus subtilis] Length = 492 Score = 261 bits (660), Expect = 1e-68 Identities = 147/479 (30%), Positives = 259/479 (53%), Gaps = 18/479 (3%) Query: 7 ILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPG 66 I+++ ++++ L+ +G Y +K D+ + GR L +V ALS A S W L+G+PG Sbjct: 6 IISLGIYFIAMLL-IGWYAFKKTTDINDYMLGGRGLGPFVTALSAGAADMSGWMLMGVPG 64 Query: 67 FAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKY-DAVTFVDYIAKRHPEAEKWIR 125 FA GL+ +W A+G +G + + A RLR E DA+T D+ KR + ++ Sbjct: 65 AMFATGLSTLWLALGLTIGAYSNYLLLAPRLRAYTEAADDAITIPDFFDKRFQHSSSLLK 124 Query: 126 ILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYT 185 I+ + I FF Y + + GG++ + FG D KLG+ +T V++ YT+ GG +V+ T Sbjct: 125 IVSALIIMIFFTLYTSSGMVSGGRLFESAFGADYKLGLFLTTAVVVLYTLFGGFLAVSLT 184 Query: 186 DTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAAIVF 245 D VQ +M L++ PIV ++ V + +L G A+++ Sbjct: 185 DFVQGAIMFAALVLVPIVAFTHVG--------GVAPTFHEIDAVNPHLLDIFKG-ASVIS 235 Query: 246 VIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGWIGIAIF 305 +I+ +W GY G P + +RFMAIKD K+ K AR IG+ W II +G+++ G IG+A Sbjct: 236 IISYLAWGLGYY-GQPHIIVRFMAIKDIKDLKPARRIGMSWMIITVLGSVLTGLIGVAYA 294 Query: 306 GPNG--LKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSENILKP 363 G +KDPE + LF P + ++ +AA++S+ S L+++++ +E++ + Sbjct: 295 HKFGVAVKDPEMIFIIFSKILFHPLITGFLLSAILAAIMSSISSQLLVTASAVTEDLYRS 354 Query: 364 YIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVIVIL 423 + ++ +A ++ +M+ RL+ + + +IA++++ + P+ I +VGY WAG G F ++L Sbjct: 355 F-FRRKASDKELVMIGRLSVLVIAVIAVLLS-LNPNSTILDLVGYAWAGFGSAFGPAILL 412 Query: 424 TLFWKRFHGKAVPPTIIAGLLFTVFWISSGLDAKVSVR--LMNFIVTFIVAIIATYAIK 480 +L+WKR + +I G + WI++GL V + FI++ I II + K Sbjct: 413 SLYWKRMNEWGALAAMIVGAATVLIWITTGLAKSTGVYEIIPGFILSMIAGIIVSMITK 471 >emb|CAA70363.1| (Y09163) proline transport system [Corynebacterium glutamicum] Length = 524 Score = 261 bits (660), Expect = 1e-68 Identities = 155/492 (31%), Positives = 252/492 (50%), Gaps = 19/492 (3%) Query: 1 MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60 M T + +V Y+ ++ +G + RK + + D+ +AGR L +VAA+S A+ S W Sbjct: 1 MSDNTWFIIAIVIYMLVMVLIGYWSYRKTEKYDDYMLAGRGLNPFVAAMSAGASDMSGWL 60 Query: 61 LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119 L+GLPG F G++ +W A+G +G W A RLR +E +++T + R + Sbjct: 61 LMGLPGALFVTGMSELWIAVGLTIGAWANWMWVAPRLRSYSEISANSITLPSFFENRLRD 120 Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179 + +RI+ + I FF FY+ + + GG + FG D LGM I A V + YT +GG Sbjct: 121 KSRALRIIAALIIIVFFTFYISSGMVAGGVYWESTFGGDYLLGMAIVAGVTVLYTFIGGF 180 Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPEL--YATSVTAALSKAGV---KYSTIL 234 +V+YTD VQ +M +LI+ P++ +AN ++ +A S G+ Y +++ Sbjct: 181 LAVSYTDAVQGTIMFFSLIIVPVMAYFALANPMDIWSFANSNDYGPHTDGIGNPTYFSMI 240 Query: 235 GGMAGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGA 294 G++ AA +I W GY G P + +RFMA++ AK R IGI W II IGA Sbjct: 241 SGISAAA----IIGNLGWGLGYF-GQPHIVVRFMALRTPAEAKQGRRIGISWMIICLIGA 295 Query: 295 LMIGWIGIAIFGPN------GLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSL 348 I F N + E + + LF P +A + +T +AA++ST S Sbjct: 296 TFTAIISTVFFAQNPDANITDTRAYESIFLDLARMLFHPLIAGLILTAVLAAIMSTMSSQ 355 Query: 349 LILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGY 408 L+++++ E++LK + K+ R +M+SR T + L IIA MA + PS I +VG+ Sbjct: 356 LLVTASSLIEDLLK-VVKKDSLSERTLIMLSRATVIILAIIAAAMA-INPSDSILGLVGF 413 Query: 409 TWAGIGDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSGLDAKVSVRLMNFIVT 468 WAG G F I++ +L+WKR + +I G + ++ W S L + + F + Sbjct: 414 AWAGFGSAFGPIILASLYWKRLNAAGAISGMITGAIVSIAWGMSPLSDTLYEIIPGFALA 473 Query: 469 FIVAIIATYAIK 480 IV ++ + K Sbjct: 474 TIVMVVVSLLTK 485 >pir||C71008 probable proline permease - Pyrococcus horikoshii >gi|3257784|dbj|BAA30467.1| (AP000006) 537aa long hypothetical proline permease [Pyrococcus horikoshii] Length = 537 Score = 257 bits (651), Expect = 1e-67 Identities = 165/501 (32%), Positives = 259/501 (50%), Gaps = 39/501 (7%) Query: 7 ILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPG 66 IL + YL L +G + R K+ + + I GR++ A LS++A+ S W +LG PG Sbjct: 5 ILLGFLIYLVLLAYIGWWANRYTKTEEQYFIGGRKVHVLAATLSDKASDFSGWLMLGYPG 64 Query: 67 FAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRI 126 AF GL A W AIGC+ G + + + RLR A K+ ++T DY+ R + K IRI Sbjct: 65 TAFKTGLGAFWAAIGCLFGTLADYLLIGPRLRIYAGKFRSITLPDYLEARLKDNTKLIRI 124 Query: 127 LGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTD 186 L +A I F YV AQ+ GGK + FG+ G+LIT +++ Y + GG +V +TD Sbjct: 125 LSAAIILIFMTAYVAAQFAAGGKTFSEAFGVSVTTGILITVIILTAYVITGGFFAVVWTD 184 Query: 187 TVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAAIVFV 246 VQA+ M+LTLI+ PI+ + I + AT + +++ A + GG G AAIVF Sbjct: 185 VVQAMFMLLTLIIMPILALAEIGGLDK--ATQIIGSVNPAKLH---PFGGATGLAAIVFA 239 Query: 247 IAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIG-WTIIAYIGALMIGWIG--IA 303 I SW GYL G P + R+M+++D + + G WT I GA G++G +A Sbjct: 240 IGYASWIVGYL-GQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALA 298 Query: 304 IFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSENILKP 363 I G + DPE+++P++ + P +A I G ++A++STADS L+++S+ + +I Sbjct: 299 INGSIKIDDPEKIVPAMAVHFLPSWIAGFVIAGIISAVMSTADSQLLVASSAIARDIYHK 358 Query: 364 YIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVIVIL 423 + E ++ + +SR+ + +IA+ A P +IY +V W G+ F I+ L Sbjct: 359 -VLGQELGKKQMVNISRVVVAIVSLIAMWFAISGPK-VIYQMVATAWGGLAVGFGPILTL 416 Query: 424 TLFWKRFHGKAVPPTIIAGLLFTVFWISSGLDAK-----------------------VSV 460 +L+WKR +A + GL+ V L+AK V V Sbjct: 417 SLWWKRVTKEAGIIGMGYGLISEVL-----LEAKIYGWAFNPNAPGFFGTLGKWFNGVPV 471 Query: 461 RLMNFIVTFIVAIIATYAIKP 481 +NF +T +V II + KP Sbjct: 472 FFINFFITLLVIIIVSLLTKP 492 >pir||A75123 proline permease (putp-2) PAB1841 - Pyrococcus abyssi (strain Orsay) >gi|5458209|emb|CAB49698.1| (AJ248285) proline permease (putP-2) [Pyrococcus abyssi] Length = 537 Score = 255 bits (644), Expect = 1e-66 Identities = 161/501 (32%), Positives = 254/501 (50%), Gaps = 39/501 (7%) Query: 7 ILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPG 66 IL + YL L +G + + K+ + + GR++ A LS++A+ S W +LG PG Sbjct: 5 ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64 Query: 67 FAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRI 126 AF AGL A W IGC+ G + + + RLR A K+ A+T DY+ R + K IRI Sbjct: 65 SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRI 124 Query: 127 LGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTD 186 L +A I F YV AQ+ GGK F + G+LIT +++ Y + GG +V +TD Sbjct: 125 LSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTD 184 Query: 187 TVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAAIVFV 246 VQA+ M+LTLI+ PI+ ++ I AT + A++ + GG G AAIVF Sbjct: 185 VVQAMFMLLTLIIMPILALVEIGGLDR--ATQIIASVDPNKLH---PFGGATGWAAIVFA 239 Query: 247 IAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIG-WTIIAYIGALMIGWIGIAIF 305 I SW GYL G P + R+M+++D + + G WT I GA G++G A+ Sbjct: 240 IGYASWIVGYL-GQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALV 298 Query: 306 GPNGLK--DPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSENILKP 363 +K DPE+++P++ + P +A I G ++A++STADS L+++S+ + +I Sbjct: 299 ASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHK 358 Query: 364 YIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVIVIL 423 + E ++ + +SR+ ++ ++A+ A P +IY +V W G+ F I+ L Sbjct: 359 -VLGQELGKKQMVNISRIVVAAVALVAMWFAITGPK-VIYQMVATAWGGLAVGFGPILTL 416 Query: 424 TLFWKRFHGKAVPPTIIAGLLFTVFWISSGLDAK-----------------------VSV 460 +L+WKR +A + GL+ V L+AK V V Sbjct: 417 SLWWKRVTKEAGIVGMAYGLISEVI-----LEAKIYGWAFNPKAPGFFGTLGQWFNGVPV 471 Query: 461 RLMNFIVTFIVAIIATYAIKP 481 +NF VT + II + KP Sbjct: 472 FFINFFVTLFIIIIVSLLTKP 492 >pir||H82382 sodium/proline symporter VCA1071 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9658517|gb|AAF96965.1| (AE004432) sodium/proline symporter [Vibrio cholerae] Length = 496 Score = 255 bits (644), Expect = 1e-66 Identities = 145/455 (31%), Positives = 243/455 (52%), Gaps = 18/455 (3%) Query: 1 MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60 ME I + YL ++++G+Y ++ K+ D+ + GR L W AALS A+ S W Sbjct: 1 MENSFAITTTFIVYLILMLAIGVYAYQRTKNSADYFLGGRSLGPWPAALSAGASDMSGWL 60 Query: 61 LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEA 120 LLGLPG+A+AAG+ + W A G ++G W V A RLR + D++T +++++R + Sbjct: 61 LLGLPGYAYAAGIESFWLAGGLLVGTWANWLVNAKRLRTYSITTDSLTLPEFLSRRFNDN 120 Query: 121 EKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLK 180 K I+ + + I FF FY + + GGK+ T+FGLD ++I + ++ YT+ GG Sbjct: 121 SKLIQTISAFFILLFFLFYTSSGLVAGGKLFETVFGLDYSTAVIIGTVCVVSYTLFGGFL 180 Query: 181 SVAYTDTVQAIVMILTLIVAPIV---GVIYIANHPELYATSVTAALSKAGVKYSTILGGM 237 +V++TD VQ ++M L++ PI G NH + A + ++ G Sbjct: 181 AVSWTDLVQGLLMAAALMIVPIAAMNGGFTQLNH------DLAAINPELLTLWNDAKGEP 234 Query: 238 AGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMI 297 A AI+ ++A W GY G P + RF A + +K+ AR I + WT ++ GA+++ Sbjct: 235 LSAIAIISLVA---WGLGYF-GQPHILARFKASRSNKDLITARRIAVVWTGLSMAGAILV 290 Query: 298 GWIGIAIF---GPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSST 354 G G+ G GL D E++ ++ LF P +A + + +AA++STADS L++SS+ Sbjct: 291 GLTGLIFVTQSGTIGLDDGEKIFMLLVNSLFHPVIAGILLAAILAAIMSTADSQLLVSSS 350 Query: 355 EFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIG 414 +E+ K ++K +A + V R+ + + +IAL +A + P + +V Y WAG G Sbjct: 351 ALAEDFYK-QVFKTDASSEDIVRVGRIAVILISLIALFLA-MTPDSSVLGLVSYAWAGFG 408 Query: 415 DTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFW 449 F ++L+L+W R + II G + V W Sbjct: 409 AAFGPALVLSLYWPRMNRHGALSGIIVGGVTIVVW 443 >pir||T44298 proline transporter [imported] - Bacillus halodurans >gi|4512352|dbj|BAA75317.1| (AB011836) proline transporter [Bacillus halodurans] >gi|10173274|dbj|BAB04379.1| (AP001509) sodium/proline symporter [Bacillus halodurans] Length = 501 Score = 252 bits (637), Expect = 6e-66 Identities = 159/493 (32%), Positives = 255/493 (51%), Gaps = 29/493 (5%) Query: 1 MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60 ME T ++ +V+ +G L+ +G+ R + D+ + GR+L G VAALS A+ S+W Sbjct: 1 MELAT-LITFIVYLVGMLV-IGLIAYRMTNNLSDYVLGGRRLGGSVAALSAGASDMSSWL 58 Query: 61 LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119 LLGLPG + G+ IW A+G +G + W A RLR E D++T D++ R + Sbjct: 59 LLGLPGALYVGGMGEIWIAVGLAIGAYLNWQFLAARLRNYTEIAKDSITLPDFLENRFHD 118 Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179 K +RI+ + I FF FY A +GG + FG+ + I A+VI+ YT +GG Sbjct: 119 KSKILRIVSALVILVFFTFYTSAGLVGGALLFEASFGMTYIQALWIGAIVIISYTFLGGF 178 Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239 +V++TD Q I+M L LI+ PIV + + E L+ G + L G Sbjct: 179 LAVSWTDFFQGILMFLALIIVPIVAINKMGGFSE--------TLNAVGAIDTAYLDAFQG 230 Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299 A ++ V + +W GY G P + RFMA+K K AR IG+ W ++A GA+ G+ Sbjct: 231 -ATVIGVASLLAWGLGYF-GQPHIVTRFMAVKSLKEIPKARFIGMTWMVLALFGAIFTGF 288 Query: 300 IGIAIFGPNGLKDPE---QVMPSVMLK----LFPPALAAVFITGAVAAMLSTADSLLILS 352 +GIA F G PE + +V + LF P +A + ++A++ST DS L++S Sbjct: 289 VGIAYFSATG-PGPEIAGEARETVFILFTQILFDPWVAGFLLAAILSAIMSTIDSQLLVS 347 Query: 353 STEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAG 412 S+ +E+ K + KN A ++ + V R V + ++A+++AY P + +VGY WAG Sbjct: 348 SSALAEDFYKGMLRKN-ASQKELVWVGRFGVVLIALVAIVLAY-NPDSTVLDLVGYAWAG 405 Query: 413 IGDTFSVIVILTLFWKRF-HGKAVPPTIIAGLLFTVF-----WISSGLDAKVSVRLMNFI 466 G F +++L+LFWKR A+ ++ G ++ W + ++ + L I Sbjct: 406 FGAAFGPVLLLSLFWKRMTRNGALAGMVVGGATVIIWAELTNWFNLSVEQYPILGLYEII 465 Query: 467 VTFIVAIIATYAI 479 FI+A IA + Sbjct: 466 PGFILASIAIIVV 478 >pir||D75188 proline symporter (proline permease). PAB2354 - Pyrococcus abyssi (strain Orsay) >gi|5457464|emb|CAB48955.1| (AJ248283) PROLINE SYMPORTER (PROLINE PERMEASE). [Pyrococcus abyssi] Length = 492 Score = 248 bits (627), Expect = 1e-64 Identities = 151/482 (31%), Positives = 251/482 (51%), Gaps = 31/482 (6%) Query: 8 LAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGF 67 L +F L I VG Y ++ KS +DF + GR + ALS ++G S+W +LGL G Sbjct: 14 LVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGM 73 Query: 68 AFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRIL 127 A+ G+ A+W A+G ++ + + RLRK +E+++A+T DY R + K +RI Sbjct: 74 AYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSKILRIA 133 Query: 128 GSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTDT 187 S I F YVGAQ+ G K L+T G+ ++I+ L+I+ Y ++GG +VAY D Sbjct: 134 ASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYNDV 193 Query: 188 VQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAAIVFVI 247 ++A++MI+ L+V P++ V + E+ V AL ++ A A +V Sbjct: 194 IRAVIMIIGLVVLPVIAVAKVGGTEEV--LKVLHALD------PKLINPWAFGAGVV--- 242 Query: 248 AEFSWFFGYLG------GMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGWIG 301 G+LG G P + +R+M+I D +++ +G W ++ GA+ +G G Sbjct: 243 ------IGFLGIGFGSPGQPHIIVRYMSIDDPNKLRVSTVVGTFWNVVLAWGAIFVGLAG 296 Query: 302 IAIFGPNGL---KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSE 358 AI K+ E + P + + FPP L + I G AA+LSTADS L++ ++ + Sbjct: 297 RAIVPDVSQLPGKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVK 356 Query: 359 NILKPYIYK-NEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTF 417 ++ + I K + D + +L +SR+T + +G +A I+AYV +I+ V + W G+G +F Sbjct: 357 DLYQEVIKKGTKIDEKTALTISRVTVLVVGFLAAILAYVA-KDIIFWFVLFAWGGLGASF 415 Query: 418 SVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSGLDAKVSVRLMNFIVTFIVAIIATY 477 +IL+L+WK V +I G + T+ W L K L + FI ++IAT Sbjct: 416 GPTLILSLYWKGTTKWGVLAGMIVGTITTIVW---KLYLKPITGLYELVPAFIFSLIATI 472 Query: 478 AI 479 + Sbjct: 473 IV 474 >pir||B69759 sodium/proline symporter ycgO - Bacillus subtilis >gi|1805394|dbj|BAA08956.1| (D50453) homologue of proline permease of E. coli [Bacillus subtilis] >gi|2632608|emb|CAB12116.1| (Z99105) similar to proline permease [Bacillus subtilis] Length = 449 Score = 238 bits (602), Expect = 8e-62 Identities = 142/437 (32%), Positives = 229/437 (51%), Gaps = 19/437 (4%) Query: 46 VAALSERATGESAWCLLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKY- 104 V ALS A S W L+GLPG F+ GL+ W IG LG W A RLR EK Sbjct: 5 VTALSAGAADMSGWLLMGLPGAMFSTGLSGAWIVIGLCLGAWANWLYVAPRLRTYTEKAG 64 Query: 105 DAVTFVDYIAKRHPEAEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGML 164 +++T ++ R + K +R+ I FF FYV + + GG + N++ G+D G+ Sbjct: 65 NSITIPGFLENRFGDQTKLLRLFSGIVILVFFTFYVSSGMVSGGVLFNSILGMDYHTGLW 124 Query: 165 ITALVILPYTVMGGLKSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALS 224 I V++ YT+ GG +V++TD VQ I+M LI+ PIV + A A + Sbjct: 125 IVTGVVVAYTLFGGFLAVSWTDFVQGIIMFAALILVPIVTFFHTGG-----AGDTVAEIR 179 Query: 225 KAGVKYSTILGGMAGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGI 284 I G +++ +I+ F+W GY G P + +RFMAI K K AR IG+ Sbjct: 180 SVDPDMFNIFKG----TSVLGIISLFAWGLGYF-GQPHIIVRFMAITSVKEIKRARRIGM 234 Query: 285 GWTIIAYIGALMIGWIGIAIFGPNG--LKDPEQVMPSVMLKLFPPALAAVFITGAVAAML 342 GW I++ +GA++ G GIA + G LKDPE + + LF P + I+ +AA++ Sbjct: 235 GWMILSAVGAVLTGLGGIAYYHQRGMTLKDPETIFIQLGNILFHPIITGFLISAILAAIM 294 Query: 343 STADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLI 402 ST S L+++S+ E++ K +++ A ++ + + RL +++ I+AL++A+ ++ I Sbjct: 295 STISSQLLVTSSSLVEDLYKS-MFRRSASDKELVFLGRLAVLAVSIVALVLAW-EKNNTI 352 Query: 403 YTIVGYTWAGIGDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSGLDAKVSVRL 462 +V Y WAG G +F +V+L+LFWKR +I G + W ++GL S L Sbjct: 353 LGLVSYAWAGFGASFGPVVLLSLFWKRMTKWGALAGMIVGAATVIIWANAGL----SDFL 408 Query: 463 MNFIVTFIVAIIATYAI 479 I F ++++ + + Sbjct: 409 YEMIPGFAASLLSVFFV 425 >gb|AAA79365.1| (U06451) proline permease homolog [Staphylococcus aureus] Length = 497 Score = 234 bits (590), Expect = 2e-60 Identities = 138/487 (28%), Positives = 246/487 (50%), Gaps = 20/487 (4%) Query: 1 MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60 ++A Q ++ Y L+ + + + ++ + GR + ++ ALS A+ S W Sbjct: 12 VDANWQTYIMIAVYFLILMLLAFTYKQATGNLSEYMLGGRSIGPYITALSAGASDMSGWM 71 Query: 61 LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKY-DAVTFVDYIAKRHPE 119 ++GLPG ++ GL+A+W IG LG + + V A RLR E DA+T D+ R + Sbjct: 72 IMGLPGSVYSTGLSAMWITIGLTLGAYINYFVVAPRLRVYTELAGDAITLPDFFKNRLND 131 Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179 ++I+ I FF Y + ++ GGK+ + FGLD G+++ A +++ YT GG Sbjct: 132 KNNVLKIISGLIIVVFFTLYTHSGFVSGGKLFESAFGLDYHFGLILVAFIVIFYTFFGGY 191 Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239 +V+ TD Q ++M++ +++ PIV ++ + + + + K + +G Sbjct: 192 LAVSITDFFQGVIMLIAMVMVPIVAMMNLNGWGTFHDVAAMKPTNLNLFKGLSFIG---- 247 Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299 +I+ FSW GY G P + +RFM+IK K AR +GI W + +GA+ +G Sbjct: 248 ------IISLFSWGLGYF-GQPHIIVRFMSIKSHKMLPKARRLGISWMAVGLLGAVAVGL 300 Query: 300 IGIAIFGPNGLK--DPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFS 357 GIA +K DPE + + LF P + + +AA++ST S L+++S+ + Sbjct: 301 TGIAFVPAYHIKLEDPETLFIVMSQVLFHPLVGGFLLAAILAAIMSTISSQLLVTSSSLT 360 Query: 358 ENILKPYIYKNEA--DPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGD 415 E+ K + +A D ++ +M+ RL+ + + I+A+ +A+ P+ I +VG WAG G Sbjct: 361 EDFYKLIRGEEKAKTDQKEFVMIGRLSVLVVAIVAIAIAW-NPNDTILNLVGNAWAGFGA 419 Query: 416 TFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWIS---SGLDAKVSVRLMNFIVTFIVA 472 +FS +V+ L+WK +++G L + WI+ L I FIV+ Sbjct: 420 SFSPLVLFALYWKGLTRAGAVSGMVSGALVVIVWIAWIKPLAHINEIFGLYEIIPGFIVS 479 Query: 473 IIATYAI 479 +I TY + Sbjct: 480 VIVTYVV 486 >pir||T48676 proline uptake protein [validated] - Staphylococcus aureus >gi|2565311|gb|AAC38087.1| (AF024571) high affinity proline permease [Staphylococcus aureus] Length = 497 Score = 231 bits (582), Expect = 2e-59 Identities = 137/487 (28%), Positives = 245/487 (50%), Gaps = 20/487 (4%) Query: 1 MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60 ++A Q ++ Y L+ + + + ++ + GR + ++ ALS A+ S W Sbjct: 12 VDANWQTYIMIAVYFLILMLLAFTYKQATGNLSEYMLGGRSIGPYITALSAGASDMSGWM 71 Query: 61 LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKY-DAVTFVDYIAKRHPE 119 ++GLPG ++ GL+A+W IG LG + + V A RLR E DA+T D+ R + Sbjct: 72 IMGLPGSVYSTGLSAMWITIGLTLGAYINYFVVAPRLRVYTELAGDAITLPDFFKNRLND 131 Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179 ++I+ I FF Y + ++ GGK+ + FGLD G+++ A +++ YT GG Sbjct: 132 KNNVLKIISGLIIIVFFTLYTHSGFVSGGKLFESAFGLDYHFGLILVAFIVIFYTFFGGY 191 Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239 +V+ TD Q ++M++ +++ PIV ++ + + + + K + +G Sbjct: 192 LAVSITDFFQGVIMLIAMVMVPIVAMMNLNGWGTFHDVAAMKPTNLNLFKGLSFIG---- 247 Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299 +I+ FSW GY G P + +RFM+IK K AR +GI W + +GA+ +G Sbjct: 248 ------IISLFSWGLGYF-GQPHIIVRFMSIKSHKMLPKARRLGISWMAVGLLGAVAVGL 300 Query: 300 IGIAIFGPNGLK--DPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFS 357 GIA +K DPE + + LF P + + +AA++ST S L+++S+ + Sbjct: 301 TGIAFVPAYHIKLEDPETLFIVMSQVLFHPLVGGFLLAAILAAIMSTISSQLLVTSSSLT 360 Query: 358 ENILKPYIYKNEA--DPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGD 415 E+ K + +A ++ +M+ RL+ + + I+A+ +A+ P+ I +VG WAG G Sbjct: 361 EDFYKLIRGEEKAKTHQKEFVMIGRLSVLVVAIVAIAIAW-NPNDTILNLVGNAWAGFGA 419 Query: 416 TFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWIS---SGLDAKVSVRLMNFIVTFIVA 472 +FS +V+ L+WK +++G L + WI+ L I FIV+ Sbjct: 420 SFSPLVLFALYWKGLTRAGAVSGMVSGALVVIVWIAWIKPLAHINEIFGLYEIIPGFIVS 479 Query: 473 IIATYAI 479 +I TY + Sbjct: 480 VIVTYVV 486 >pir||B81297 sodium/proline symporter Cj1502c [imported] - Campylobacter jejuni (strain NCTC 11168) >gi|6968927|emb|CAB73923.1| (AL139078) sodium/proline symporter [Campylobacter jejuni] Length = 495 Score = 229 bits (577), Expect = 7e-59 Identities = 142/482 (29%), Positives = 250/482 (51%), Gaps = 22/482 (4%) Query: 1 MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60 ++ T I + V Y ++ +G Y ++ K+ +D+ + GR + ++ALS A+ S W Sbjct: 10 VQINTPIAVMFVVYALLMLYIGFYFYKQNKNSEDYFLGGRTMGPVISALSAGASDMSGWL 69 Query: 61 LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKY-DAVTFVDYIAKRHPE 119 L+GLPG + +G + AIG +G + W A RLR +++T DY R + Sbjct: 70 LMGLPGALYVSGFIDSYIAIGLTIGASLNWIFVAKRLRIYTSVIANSLTIPDYFETRFDD 129 Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179 + +RI+ + I FF FYV + + G K+ + FG+ + ++I+ YT +GG Sbjct: 130 DKHILRIVCAVVILIFFTFYVSSGLVSGAKLFESTFGIRYDYALTTGTIIIVAYTFLGGY 189 Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239 K+V +TD +Q ++M++ LI+ P+V + ++ E A ++ + + M Sbjct: 190 KAVCWTDMIQGLLMMMALIIVPLVMLYHLGGFGE--AMNIVREIKPQAL-------SMGE 240 Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299 IV +I+ +W GY G P + +RFM+I+ K+ +A IGI W + + A MIG Sbjct: 241 GVGIVSIISALAWGLGYF-GQPHILVRFMSIRSTKDIPMATFIGIAWMAVCLLSACMIGI 299 Query: 300 IGIAIFG--PNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFS 357 +GIA L+DPE++ + LF P +A + ++ +AA++STA S L++SS+ + Sbjct: 300 LGIAYVHKFELSLQDPEKIFIVMSQLLFNPWIAGILLSAILAAIMSTASSQLLVSSSTIA 359 Query: 358 ENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTF 417 E+ K I++ +A L + +L + + +IA +++ S ++ +IV Y WAG G +F Sbjct: 360 EDFYKK-IFREDAPSHIVLNLGKLGVLLVAVIAFLISTDKNSSVL-SIVSYAWAGFGASF 417 Query: 418 SVIVILTLFWKRFHGKAVPPTIIAGLLFTVFW---ISSGLDAKVSVRLMNFIVTFIVAII 474 +++ +LFW R +I G V W +SGL V F+V +V II Sbjct: 418 GSVMLFSLFWSRMTRVGAILGMITGAATVVLWKNFANSGLYEIVP----GFLVASVVIII 473 Query: 475 AT 476 A+ Sbjct: 474 AS 475 >pir||G81202 sodium/proline symporter NMB0402 [imported] - Neisseria meningitidis (group B strain MD58, group A strain Z2491) >gi|7225624|gb|AAF40841.1| (AE002396) sodium/proline symporter [Neisseria meningitidis MC58] >gi|7380708|emb|CAB85299.1| (AL162758) sodium/proline symporter [Neisseria meningitidis Z2491] Length = 508 Score = 228 bits (576), Expect = 9e-59 Identities = 143/482 (29%), Positives = 248/482 (50%), Gaps = 28/482 (5%) Query: 14 YLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGFAFAAGL 73 YL ++ +G+ ++ D+ + GR L +V A+S A+ S W L+GLPG + +GL Sbjct: 11 YLVAVLLIGLAAYFSTRNFDDYILGGRSLGPFVTAMSAGASDMSGWLLMGLPGAIYLSGL 70 Query: 74 AAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPEAEKWIRILGSATI 132 W AIG ++G W + AGRLR E +A+T DY R ++++ + I Sbjct: 71 NEAWIAIGLLVGAYFNWLLVAGRLRVHTEYANNALTLPDYFFHRFGAGGHLMKVVSALII 130 Query: 133 AFFFFFYVGAQYLGGGKVLNTLF-GLDPKLGMLITALVILPYTVMGGLKSVAYTDTVQAI 191 FFF Y + + G + +LF G+ M + A + YT +GG +V++TDT+QA Sbjct: 131 LFFFTIYCASGIVAGATLFQSLFEGMTYNQAMWLGAGATIAYTFLGGFLAVSWTDTLQAS 190 Query: 192 VMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAAIVFVIAEFS 251 +MI LI+ P++ + + ++ A ++ + + G +Y ++ G ++ +I+ + Sbjct: 191 LMIFALILTPVMVYLGLGGAEQMSA-AIQSVAAGTGKEYGSLFAG----TTVIGIISTAA 245 Query: 252 WFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGWIGIAIFGPNGLK 311 W GY G P + RFMA + K+ AR IG+ W + GA+ +G+ GIA FG N K Sbjct: 246 WGLGYF-GQPHILARFMAAESAKSLVSARRIGMTWMALCLAGAVAVGYFGIAYFGANPDK 304 Query: 312 ------DPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSENILKPYI 365 + E++ ++ LF P +A + ++ +AA++ST L++ S+ +E+ K ++ Sbjct: 305 VSSMSGNHERIFIALSTLLFNPWIAGIILSAILAAVMSTLSCQLLVCSSAITEDFYKGFL 364 Query: 366 YKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVIVILTL 425 KN A + + V RL +++ +I++++A P+ + +V Y WAG G F IVIL++ Sbjct: 365 RKN-AQQSELVWVGRLMVLAIAVISILIA-SDPNSKVLGLVSYAWAGFGAAFGPIVILSV 422 Query: 426 FWKRFHGKAVPPTIIAGLLFTVFWI-----------SSGLDAKVSVRLMNFIVTFIVAII 474 WKR ++AG L V W SGL + + FIV IVA++ Sbjct: 423 LWKRITAYGALSGMVAGALTVVVWAEWVKKPAQAAGESGLLTMYEI-VPGFIVCLIVAVL 481 Query: 475 AT 476 + Sbjct: 482 VS 483 >pir||JC2382 sodium/proline symporter - Pseudomonas fluorescens >gi|509694|dbj|BAA06838.1| (D32069) proline permease [Pseudomonas fluorescens] >gi|913690|gb|AAC60490.1| (S76070) proline permease [Pseudomonas fluorescens, Peptide, 494 aa] >gi|1092517|prf||2024229A Pro permease [Pseudomonas fluorescens] Length = 494 Score = 228 bits (575), Expect = 1e-58 Identities = 144/487 (29%), Positives = 236/487 (47%), Gaps = 26/487 (5%) Query: 1 MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60 M L V Y+ ++ +G+ R + D+ + GR L V ALS A+ S W Sbjct: 1 MSVSNPTLITFVIYIAAMVLIGLMAYRSTNNLSDYILGGRSLGSVVTALSAGASDMSGWL 60 Query: 61 LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119 L+GLPG + +GL+ W AIG ++G + W AGRLR + E DA+T DY + R + Sbjct: 61 LMGLPGAIYMSGLSESWIAIGLIVGAYLNWLFVAGRLRVQTEHNGDALTLPDYFSSRFED 120 Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179 +RI+ + I FF Y + + G ++ + FG+ + + A + YT +GG Sbjct: 121 KSGLLRIISAVVILVFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIAYTFIGGF 180 Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELY-ATSVTAALSKAGVKYSTILGGMA 238 +V++TDTVQA +MI LI+ PI+ ++ + A S +K +T +G Sbjct: 181 LAVSWTDTVQATLMIFALILTPIIVLLATGGVDTTFLAIEAKDPTSFDMLKNTTFIG--- 237 Query: 239 GAAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIG 298 +I+ W GY G P + RFMA K+ AR I + W I+ G + +G Sbjct: 238 -------IISLMGWGLGYF-GQPHILARFMAADSVKSIAKARRISMTWMILCLGGTVAVG 289 Query: 299 WIGIAIFGPNG------LKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILS 352 + GIA F + ++PE+V + LF P +A V ++ +AA++ST L++ Sbjct: 290 FFGIAYFSAHPEVAGPVTENPERVFIELAKILFNPWVAGVLLSAILAAVMSTLSCQLLVC 349 Query: 353 STEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAG 412 S+ +E+ K ++ K A R+ + V RL + + +IA+ MA P + + +V Y WAG Sbjct: 350 SSALTEDFYKAFLRKG-ASQRELVWVGRLMVLVVALIAIAMA-ANPENRVLGLVSYAWAG 407 Query: 413 IGDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSGLDAKVSVRLMNFIVTFIVA 472 G F +V++++ WK I+ G + + W L + L I FI A Sbjct: 408 FGAAFGPVVLISVIWKHMTRNGALAGILVGAITVIVWKHFEL-----LGLYEIIPGFIFA 462 Query: 473 IIATYAI 479 +A Y + Sbjct: 463 SLAIYFV 469 >pir||F83547 sodium/proline symporter PutP PA0783 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9946673|gb|AAG04172.1|AE004513_4 (AE004513) sodium/proline symporter PutP [Pseudomonas aeruginosa] Length = 506 Score = 227 bits (573), Expect = 2e-58 Identities = 137/456 (30%), Positives = 226/456 (49%), Gaps = 19/456 (4%) Query: 1 MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60 M T L V Y+ ++ +G+ R + D+ + GR L +V ALS A+ S W Sbjct: 1 MSVNTPTLITFVIYIAAMVLIGLAAYRSTNNFSDYILGGRSLGSFVTALSAGASDMSGWL 60 Query: 61 LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119 L+GLPG + +GL+ W AIG ++G + W AGRLR + E +A+T DY R + Sbjct: 61 LMGLPGAVYLSGLSESWIAIGLIVGAYLNWLFVAGRLRVQTEHNGNALTLPDYFTNRFED 120 Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179 + +RI + I FF Y + + G ++ + FGL + + A + YT +GG Sbjct: 121 NSRLLRIFSALVILVFFTIYCASGIVAGARLFESTFGLSYETALWAGAAATIAYTFIGGF 180 Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239 +V++TDTVQA +MI LI+ P++ ++ + TA K + + G Sbjct: 181 LAVSWTDTVQASLMIFALILTPVIVMLATGG----VEPTFTAIELKDATSFDMLKG---- 232 Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299 A+ + VI+ +W GY G P + RFMA K+ AR I + W I+ GA+ +G+ Sbjct: 233 -ASFIGVISLMAWGLGYF-GQPHILARFMAADSVKSIPAARRISMTWMILCLGGAVAVGF 290 Query: 300 IGIAIFGPNG------LKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353 GIA F + ++PE+V + LF P +A V ++ +AA++ST L++ S Sbjct: 291 FGIAYFQAHPEQAGAVSENPERVFIELAKILFNPWIAGVLLSAILAAVMSTLSCQLLVCS 350 Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413 + +E+ K ++ K A + + V R + + +IA+ +A P + + +V Y WAG Sbjct: 351 SALTEDFYKAFLRKG-ASQLELVWVGRAMVLLVAVIAIWLA-SNPENRVLGLVSYAWAGF 408 Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFW 449 G F +V+ +L WKR +I G + W Sbjct: 409 GAAFGPLVLFSLLWKRMTRNGALAGMIVGAATVILW 444 >pir||A71980 sodium/proline symporter - Helicobacter pylori (strain J99) >gi|4154554|gb|AAD05631.1| (AE001444) sodium/proline symporter [Helicobacter pylori J99] Length = 496 Score = 226 bits (571), Expect = 4e-58 Identities = 138/478 (28%), Positives = 247/478 (50%), Gaps = 20/478 (4%) Query: 5 TQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGL 64 T I+ + V Y ++ +G Y ++ ++ +D+ + R + ++ALS A+ S W L+GL Sbjct: 8 TPIVTMFVVYSLLMLYIGFYFYKQNETTEDYFLGDRSMGPVISALSAGASDMSGWLLMGL 67 Query: 65 PGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKY-DAVTFVDYIAKRHPEAEKW 123 PG + GL AIG LG ++ W A RLR +++T DY R + + Sbjct: 68 PGALYVGGLINSHIAIGLSLGALINWVFVAKRLRIYTSVIANSITISDYFETRFSDDKHI 127 Query: 124 IRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVA 183 +R++ + I FF FY+ + + G K+ FG+ + I L+I+ YT +GG K+V Sbjct: 128 LRLISAFVILIFFIFYISSGLVSGAKLFEATFGIQYTYALSIGTLIIVSYTFLGGYKAVC 187 Query: 184 YTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAAI 243 +TD +Q ++M+ LIV PIV +I++ E + + + + +++ Sbjct: 188 WTDLIQGLLMMSALIVVPIVMIIHLGGIGE--GIKIIREIKPENLSF-------LQGSSV 238 Query: 244 VFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGWIGIA 303 V +I+ +W GY G P + +RFM+I+ ++ A IGI W +I+ IGA ++G +G+A Sbjct: 239 VAIISSLAWGLGYF-GQPHILVRFMSIRSIRDVPKATTIGISWMVISLIGACVMGLLGVA 297 Query: 304 IFG--PNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSENIL 361 L+DPE++ + LF P + + ++ +AA++STA S L++SS+ +E+ Sbjct: 298 YVHKFDLSLEDPEKIFIVMSQLLFNPWITGILLSAILAAVMSTASSQLLVSSSTIAEDFY 357 Query: 362 KPYIYKNEADPRKSLM-VSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVI 420 KN P+K +M +SRL+ + + IA ++ + I +IV Y WAG G +F + Sbjct: 358 ATIFNKNA--PQKLVMTISRLSVLGVACIAFFIS-TDKNASILSIVSYAWAGFGASFGSV 414 Query: 421 VILTLFWKRFHGKAVPPTIIAGLLFTVFWISSGLDAKVSVRLMNFIVTFIVAIIATYA 478 ++ +LFW R +++G + + G K + + + FIVA +A A Sbjct: 415 ILFSLFWSRMTRIGAIAGMLSGASTVILYDKFG---KSFLDIYEIVPGFIVASVAIVA 469 >pir||G64526 sodium/proline symporter - Helicobacter pylori (strain 26695) >gi|2313133|gb|AAD07125.1| (AE000527) proline permease (putP) [Helicobacter pylori 26695] Length = 496 Score = 224 bits (566), Expect = 1e-57 Identities = 133/474 (28%), Positives = 245/474 (51%), Gaps = 18/474 (3%) Query: 5 TQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGL 64 T I+ + + Y ++ +G Y ++ ++ +D+ + R + ++ALS A+ S W L+GL Sbjct: 8 TPIVTMFIVYSLLMLYIGFYFYKQNETTEDYFLGDRSMGPVISALSAGASDMSGWLLMGL 67 Query: 65 PGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKY-DAVTFVDYIAKRHPEAEKW 123 PG + GL AIG LG ++ W A RLR +++T DY R + + Sbjct: 68 PGALYVGGLINSHIAIGLSLGALINWVFVAKRLRIYTSVIANSITISDYFETRFSDDKHI 127 Query: 124 IRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVA 183 +R++ + I FF FY+ + + G K+ FG+ + I L+I+ YT +GG K+V Sbjct: 128 LRLISAFVILIFFIFYISSGLVSGAKLFEATFGIQYTYALSIGTLIIVSYTFLGGYKAVC 187 Query: 184 YTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAAI 243 +TD +Q ++M+ LIV PIV +I++ E + + + + +++ Sbjct: 188 WTDLIQGLLMMSALIVVPIVMIIHLGGIGE--GIKIIREIKPENLSF-------LQGSSV 238 Query: 244 VFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGWIGIA 303 V +I+ +W GY G P + +RFM+I+ ++ A IGI W +I+ IGA ++G +G+A Sbjct: 239 VAIISSLAWGLGYF-GQPHILVRFMSIRSIRDVPKATTIGISWMVISLIGACVMGLLGVA 297 Query: 304 IFG--PNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSENIL 361 L+DPE++ + LF P + + ++ +AA++STA S L++SS+ +E+ Sbjct: 298 YVHKFDLSLEDPEKIFIVMSQLLFNPWITGILLSAILAAVMSTASSQLLVSSSTIAEDFY 357 Query: 362 KPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVIV 421 I+ +A + + +SRL+ + + IA ++ + I +IV Y WAG G +F ++ Sbjct: 358 AT-IFNKDAPQKLVMAISRLSVLGVACIAFFIS-TDRNASILSIVSYAWAGFGASFGSVI 415 Query: 422 ILTLFWKRFHGKAVPPTIIAGLLFTVFWISSGLDAKVSVRLMNFIVTFIVAIIA 475 + +LFW R +++G + + G K + + + FIVA +A Sbjct: 416 LFSLFWSRMTRIGAIAGMLSGASTVILYDKFG---KSFLDIYEIVPGFIVASVA 466 >pir||S10220 sodium/proline symporter - Salmonella typhimurium Length = 502 Score = 224 bits (565), Expect = 2e-57 Identities = 134/460 (29%), Positives = 230/460 (49%), Gaps = 19/460 (4%) Query: 1 MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60 M T +L Y+ +I +G R K+ D+ + GR L +V ALS A+ S W Sbjct: 1 MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60 Query: 61 LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119 L+GLPG F +G++ W AIG LG + W + AGRLR E +A+T DY R + Sbjct: 61 LMGLPGAIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFED 120 Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179 + +RI+ + I FF Y G+ + G ++ + FG+ + + A + YT +GG Sbjct: 121 KSRVLRIISALVILLFFTIYCGSGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGF 180 Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239 +V++TDTVQA +MI LI+ P++ ++ + E + + ++ +L G+ Sbjct: 181 LAVSWTDTVQASLMIFALILTPVMVIVGVGGFSE-----SLEVIKQKSIENVDMLKGL-- 233 Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299 V +I+ W GY G P + RFMA + AR I + W I+ GA+ +G+ Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGF 290 Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353 GIA F N ++ E+V + LF P +A V ++ +AA++ST +++ S Sbjct: 291 FGIAYFNNNPALAGAVNQNSERVFIELAQILFNPWIAGVLLSAILAAVMSTLSCQMLVCS 350 Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413 + +E++ K ++ K+ A ++ + V R+ + + +IA+ +A P + + +V Y WAG Sbjct: 351 SAITEDLYKAFLRKS-ASQQELVWVGRVMVLVVALIAIALA-ANPDNRVLGLVSYAWAGF 408 Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453 G F +V+ ++ W R +I G + + W G Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGAVTVIVWKQYG 448 >gb|AAA24461.1| (L01132) proline permease [Escherichia coli] >gi|147447|gb|AAA24467.1| (L01154) proline permease [Escherichia coli] >gi|147451|gb|AAA24469.1| (L01156) proline permease [Escherichia coli] Length = 489 Score = 223 bits (562), Expect = 4e-57 Identities = 134/460 (29%), Positives = 231/460 (50%), Gaps = 19/460 (4%) Query: 1 MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60 M T +L Y+ +I +G R K+ D+ + GR L +V ALS A+ S W Sbjct: 1 MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60 Query: 61 LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119 L+GLPG F +G++ W AIG LG + W + AGRLR E +A+T DY R + Sbjct: 61 LMGLPGAVFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEYNNNALTLPDYFTGRFED 120 Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179 + +RI+ + I FF Y + + G ++ + FG+ + + A + YT +GG Sbjct: 121 KSRILRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATILYTFIGGF 180 Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239 +V++TDTVQA +MI LI+ P++ +I + + S+ K+ ++ +L G+ Sbjct: 181 LAVSWTDTVQASLMIFALILTPVIVIISVGG----FGDSLEVIKQKS-IENVDMLKGL-- 233 Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299 V +I+ W GY G P + RFMA + AR I + W I+ GA+ +G+ Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGF 290 Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353 GIA F + ++ E+V + LF P +A + ++ +AA++ST L++ S Sbjct: 291 FGIAYFNEHPAVAGAVNQNAERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCS 350 Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413 + +E++ K ++ K +A ++ + V R+ + + ++A+ +A P + + +V Y WAG Sbjct: 351 SAITEDLYKAFLRK-QASQKELVWVGRVMVLVVALVAIALA-ANPENRVLGLVSYAWAGF 408 Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453 G F +V+ ++ W R +I G L + W G Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGALTVIVWKQFG 448 >sp|P07117|PUTP_ECOLI SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE) >gi|72512|pir||JGECPP sodium/proline symporter - Escherichia coli >gi|42602|emb|CAA29143.1| (X05653) putP proline carrier (AA 1-502) [Escherichia coli] >gi|1651504|dbj|BAA35793.1| (D90738) Proline carrier protein [Escherichia coli] >gi|1787251|gb|AAC74100.1| (AE000203) major sodium/proline symporter [Escherichia coli K12] >gi|225963|prf||1404369A Pro carrier protein [Escherichia coli] Length = 502 Score = 222 bits (561), Expect = 5e-57 Identities = 134/460 (29%), Positives = 231/460 (50%), Gaps = 19/460 (4%) Query: 1 MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60 M T +L Y+ +I +G R K+ D+ + GR L +V ALS A+ S W Sbjct: 1 MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60 Query: 61 LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119 L+GLPG F +G++ W AIG LG + W + AGRLR E +A+T DY R + Sbjct: 61 LMGLPGAVFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEYNNNALTLPDYFTGRFED 120 Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179 + +RI+ + I FF Y + + G ++ + FG+ + + A + YT +GG Sbjct: 121 KSRILRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATILYTFIGGF 180 Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239 +V++TDTVQA +MI LI+ P++ +I + + S+ K+ ++ +L G+ Sbjct: 181 LAVSWTDTVQASLMIFALILTPVIVIISVGG----FGDSLEVIKQKS-IENVDMLKGL-- 233 Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299 V +I+ W GY G P + RFMA + AR I + W I+ GA+ +G+ Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGF 290 Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353 GIA F + ++ E+V + LF P +A + ++ +AA++ST L++ S Sbjct: 291 FGIAYFNDHPALAGAVNQNAERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCS 350 Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413 + +E++ K ++ K+ A ++ + V R+ + + ++A+ +A P + + +V Y WAG Sbjct: 351 SAITEDLYKAFLRKH-ASQKELVWVGRVMVLVVALVAIALA-ANPENRVLGLVSYAWAGF 408 Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453 G F +V+ ++ W R +I G L + W G Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGALTVIVWKQFG 448 >sp|P10502|PUTP_SALTY SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE) >gi|47849|emb|CAA36802.1| (X52573) proline permease (AA 1-502) [Salmonella typhimurium] Length = 502 Score = 222 bits (561), Expect = 5e-57 Identities = 134/460 (29%), Positives = 229/460 (49%), Gaps = 19/460 (4%) Query: 1 MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60 M T +L Y+ +I +G R K+ D+ + GR L +V ALS A+ S W Sbjct: 1 MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60 Query: 61 LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119 L+GLPG F +G++ W AIG LG + W + AGRLR E +A+T DY R + Sbjct: 61 LMGLPGAIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFED 120 Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179 + +RI+ + I FF Y + + G ++ + FG+ + + A + YT +GG Sbjct: 121 KSRVLRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGF 180 Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239 +V++TDTVQA +MI LI+ P++ ++ + E + + ++ +L G+ Sbjct: 181 LAVSWTDTVQASLMIFALILTPVMVIVGVGGFSE-----SLEVIKQKSIENVDMLKGL-- 233 Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299 V +I+ W GY G P + RFMA + AR I + W I+ GA+ +G+ Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGF 290 Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353 GIA F N ++ E+V + LF P +A V ++ +AA++ST L++ S Sbjct: 291 FGIAYFNNNPALAGAVNQNSERVFIELAQILFNPWIAGVLLSAILAAVMSTLSCQLLVCS 350 Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413 + +E++ K ++ K+ A ++ + V R+ + + +IA+ +A P + + +V Y WAG Sbjct: 351 SAITEDLYKAFLRKS-ASQQELVWVGRVMVLVVALIAIALA-ANPDNRVLGLVSYAWAGF 408 Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453 G F +V+ ++ W R +I G + + W G Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGAVTVIVWKQYG 448 >gb|AAA99288.1| (L01146) proline permease [Salmonella sp.] >gi|154314|gb|AAA99289.1| (L01147) proline permease [Salmonella sp.] Length = 489 Score = 222 bits (561), Expect = 5e-57 Identities = 133/460 (28%), Positives = 230/460 (49%), Gaps = 19/460 (4%) Query: 1 MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60 M T +L Y+ +I +G R K+ D+ + GR L +V ALS A+ S W Sbjct: 1 MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60 Query: 61 LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119 L+GLPG F +G++ W AIG LG + W + AGRLR E +A+T DY R + Sbjct: 61 LMGLPGAIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFED 120 Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179 + +RI+ + I FF Y + + G ++ + FG+ + + A + YT +GG Sbjct: 121 KSRVLRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGF 180 Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239 +V++TDTVQA +MI LI+ P++ ++ + E + + ++ +L G+ Sbjct: 181 LAVSWTDTVQASLMIFALILTPVMVIVGVGGFSE-----SLEVIKQKSIENVDMLKGL-- 233 Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299 V +I+ W GY G P + RFMA + AR I + W I+ GA+ +G+ Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGF 290 Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353 GIA F N ++ E+V + LF P +A + ++ +AA++ST L++ S Sbjct: 291 FGIAYFNNNPALAGAVNQNSERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCS 350 Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413 + +E++ K ++ K+ A ++ + V R+ + + +IA+ +A P++ + +V Y WAG Sbjct: 351 SAITEDLYKAFLRKS-ASQQELVWVGRVMVLVVALIAIALA-ANPNNRVLGLVSYAWAGF 408 Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453 G F +V+ ++ W R +I G + + W G Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGAVTVIVWKQYG 448 >gb|AAA24463.1| (L01150) proline permease [Escherichia coli] >gi|147441|gb|AAA24464.1| (L01151) proline permease [Escherichia coli] Length = 489 Score = 222 bits (561), Expect = 5e-57 Identities = 134/460 (29%), Positives = 231/460 (50%), Gaps = 19/460 (4%) Query: 1 MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60 M T +L Y+ +I +G R K+ D+ + GR L +V ALS A+ S W Sbjct: 1 MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60 Query: 61 LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119 L+GLPG F +G++ W AIG LG + W + AGRLR E +A+T DY R + Sbjct: 61 LMGLPGAVFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEYNNNALTLPDYFTGRFED 120 Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179 + +RI+ + I FF Y + + G ++ + FG+ + + A + YT +GG Sbjct: 121 KSRILRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATILYTFIGGF 180 Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239 +V++TDTVQA +MI LI+ P++ +I + + S+ K+ ++ +L G+ Sbjct: 181 LAVSWTDTVQASLMIFALILTPVIVIISVGG----FGDSLEVIKQKS-IENVDMLKGL-- 233 Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299 V +I+ W GY G P + RFMA + AR I + W I+ GA+ +G+ Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGF 290 Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353 GIA F + ++ E+V + LF P +A + ++ +AA++ST L++ S Sbjct: 291 FGIAYFNDHPALAGAVNQNAERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCS 350 Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413 + +E++ K ++ K+ A ++ + V R+ + + ++A+ +A P + + +V Y WAG Sbjct: 351 SAITEDLYKAFLRKH-ASQKELVWVGRVMVLVVALVAIALA-ANPENRVLGLVSYAWAGF 408 Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453 G F +V+ ++ W R +I G L + W G Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGALTVIVWKQFG 448 >gb|AAA27199.1| (L01135) proline permease [Salmonella typhimurium] Length = 489 Score = 222 bits (561), Expect = 5e-57 Identities = 134/460 (29%), Positives = 229/460 (49%), Gaps = 19/460 (4%) Query: 1 MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60 M T +L Y+ +I +G R K+ D+ + GR L +V ALS A+ S W Sbjct: 1 MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60 Query: 61 LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119 L+GLPG F +G++ W AIG LG + W + AGRLR E +A+T DY R + Sbjct: 61 LMGLPGAIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFED 120 Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179 + +RI+ + I FF Y + + G ++ + FG+ + + A + YT +GG Sbjct: 121 KSRVLRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGF 180 Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239 +V++TDTVQA +MI LI+ P++ ++ + E + + ++ +L G+ Sbjct: 181 LAVSWTDTVQASLMIFALILTPVMVIVGVGGFSE-----SLEVIKQKSIENVDMLKGL-- 233 Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299 V +I+ W GY G P + RFMA + AR I + W I+ GA+ +G+ Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGF 290 Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353 GIA F N ++ E+V + LF P +A V ++ +AA++ST L++ S Sbjct: 291 FGIAYFNNNPALAGAVNQNSERVFIELAQILFNPWIAGVLLSAILAAVMSTLSCQLLVCS 350 Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413 + +E++ K ++ K+ A ++ + V R+ + + +IA+ +A P + + +V Y WAG Sbjct: 351 SAITEDLYKAFLRKS-ASQQELVWVGRVMVLVVALIAIALA-ANPDNRVLGLVSYAWAGF 408 Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453 G F +V+ ++ W R +I G + + W G Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGAVTVIVWKQYG 448 >gb|AAA26389.1| (L01134) proline permease [Rickettsia typhi] Length = 489 Score = 222 bits (561), Expect = 5e-57 Identities = 134/460 (29%), Positives = 229/460 (49%), Gaps = 19/460 (4%) Query: 1 MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60 M T +L Y+ +I +G R K+ D+ + GR L +V ALS A+ S W Sbjct: 1 MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60 Query: 61 LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119 L+GLPG F +G++ W AIG LG + W + AGRLR E +A+T DY R + Sbjct: 61 LMGLPGAIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFED 120 Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179 + +RI+ + I FF Y + + G ++ + FG+ + + A + YT +GG Sbjct: 121 KSRVLRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGF 180 Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239 +V++TDTVQA +MI LI+ P++ ++ + E + + ++ +L G+ Sbjct: 181 LAVSWTDTVQASLMIFALILTPVMVIVGVGGFSE-----SLEVIKQKSIENVDMLKGL-- 233 Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299 V +I+ W GY G P + RFMA + AR I + W I+ GA+ +G+ Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGF 290 Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353 GIA F N ++ E+V + LF P +A V ++ +AA++ST L++ S Sbjct: 291 FGIAYFNNNPALAGAVNQNSERVFIELAQILFNPWIAGVLLSAILAAVMSTLSCQLLVCS 350 Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413 + +E++ K ++ K+ A ++ + V R+ + + +IA+ +A P + + +V Y WAG Sbjct: 351 SAITEDLYKAFLRKS-ASQQELVWVGRVMVLVVALIAIALA-ANPDNRVLGLVSYAWAGF 408 Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453 G F +V+ ++ W R +I G + + W G Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGAVTVIVWKQYG 448 >gb|AAA99282.1| (L01140) proline permease [Salmonella sp.] >gi|154302|gb|AAA99283.1| (L01141) proline permease [Salmonella sp.] Length = 489 Score = 222 bits (561), Expect = 5e-57 Identities = 133/460 (28%), Positives = 229/460 (48%), Gaps = 19/460 (4%) Query: 1 MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60 M T +L Y+ ++ +G R K+ D+ + GR L +V ALS A+ S W Sbjct: 1 MAISTPMLVTFCVYIFGMLLIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60 Query: 61 LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119 L+GLPG F +G++ W AIG LG + W + AGRLR E +A+T DY R + Sbjct: 61 LMGLPGAIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTSRFED 120 Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179 + +RI+ + I FF Y + + G ++ + FG+ + + A + YT +GG Sbjct: 121 KSRVLRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGF 180 Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239 +V++TDTVQA +MI LI+ P++ ++ + E + + ++ +L G+ Sbjct: 181 LAVSWTDTVQASLMIFALILTPVMVIVGVGGFSE-----SLEVIKQKSIENVDMLKGL-- 233 Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299 V +I+ W GY G P + RFMA + AR I + W I+ GA+ +G+ Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHHSIVHARRISMTWMILCLTGAVAVGF 290 Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353 GIA F N ++ E+V + LF P +A V ++ +AA++ST L++ S Sbjct: 291 FGIAFFNNNPALAGAVNQNSERVFIELAQILFNPWIAGVLLSAILAAVMSTLSCQLLVCS 350 Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413 + +E++ K ++ K+ A ++ + V R+ + + +IA+ +A P + + +V Y WAG Sbjct: 351 SAITEDLYKAFLRKS-AGQQELVWVGRVMVLVVALIAIALA-ANPDNRVLGLVSYAWAGF 408 Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453 G F +V+ ++ W R +I G + + W G Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGAVTVIVWKQYG 448 >gb|AAA24466.1| (L01153) proline permease [Escherichia coli] >gi|147453|gb|AAA24470.1| (L01157) proline permease [Escherichia coli] >gi|147455|gb|AAA24471.1| (L01158) proline permease [Escherichia coli] >gi|147457|gb|AAA24472.1| (L01159) proline permease [Escherichia coli] Length = 489 Score = 222 bits (561), Expect = 5e-57 Identities = 134/460 (29%), Positives = 231/460 (50%), Gaps = 19/460 (4%) Query: 1 MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60 M T +L Y+ +I +G R K+ D+ + GR L +V ALS A+ S W Sbjct: 1 MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60 Query: 61 LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119 L+GLPG F +G++ W AIG LG + W + AGRLR E +A+T DY R + Sbjct: 61 LMGLPGAVFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEYNNNALTLPDYFTGRFED 120 Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179 + +RI+ + I FF Y + + G ++ + FG+ + + A + YT +GG Sbjct: 121 KSRILRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATILYTFIGGF 180 Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239 +V++TDTVQA +MI LI+ P++ +I + + S+ K+ ++ +L G+ Sbjct: 181 LAVSWTDTVQASLMIFALILTPVIVIISVGG----FGDSLEVIKQKS-IENVDMLKGL-- 233 Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299 V +I+ W GY G P + RFMA + AR I + W I+ GA+ +G+ Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGF 290 Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353 GIA F + ++ E+V + LF P +A + ++ +AA++ST L++ S Sbjct: 291 FGIAYFNEHPAVAGAVNQNAERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCS 350 Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413 + +E++ K ++ K+ A ++ + V R+ + + ++A+ +A P + + +V Y WAG Sbjct: 351 SAITEDLYKAFLRKH-ASQKELVWVGRVMVLVVALVAIALA-ANPENRVLGLVSYAWAGF 408 Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453 G F +V+ ++ W R +I G L + W G Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGALTVIVWKQFG 448 >gb|AAA24462.1| (L01133) proline permease [Escherichia coli] Length = 489 Score = 222 bits (560), Expect = 7e-57 Identities = 134/460 (29%), Positives = 231/460 (50%), Gaps = 19/460 (4%) Query: 1 MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60 M T +L Y+ +I +G R K+ D+ + GR L +V ALS A+ S W Sbjct: 1 MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60 Query: 61 LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119 L+GLPG F +G++ W AIG LG + W + AGRLR E +A+T DY R + Sbjct: 61 LMGLPGAVFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEYNNNALTLPDYFTGRFED 120 Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179 + +RI+ + I FF Y + + G ++ + FG+ + + A + YT +GG Sbjct: 121 KSRILRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATILYTFIGGF 180 Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239 +V++TDTVQA +MI LI+ P++ +I + + S+ K+ ++ +L G+ Sbjct: 181 LAVSWTDTVQASLMIFALILTPVIVIISVGG----FGDSLEVIKQKS-IENVDMLKGL-- 233 Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299 V +I+ W GY G P + RFMA + AR I + W I+ GA+ +G+ Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGF 290 Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353 GIA F + ++ E+V + LF P +A + ++ +AA++ST L++ S Sbjct: 291 FGIAYFNEHPSVAGAVNQNAERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCS 350 Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413 + +E++ K ++ K+ A ++ + V R+ + + ++A+ +A P + + +V Y WAG Sbjct: 351 SAITEDLYKAFLRKH-ASQKELVWVGRVMVLVVALVAIALA-ANPENRVLGLVSYAWAGF 408 Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453 G F +V+ ++ W R +I G L + W G Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGALTVIVWKQFG 448 >gb|AAA24468.1| (L01155) proline permease [Escherichia coli] Length = 489 Score = 222 bits (560), Expect = 7e-57 Identities = 134/460 (29%), Positives = 231/460 (50%), Gaps = 19/460 (4%) Query: 1 MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60 M T +L Y+ +I +G R K+ D+ + GR L +V ALS A+ S W Sbjct: 1 MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60 Query: 61 LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119 L+GLPG F +G++ W AIG LG + W + AGRLR E +A+T DY R + Sbjct: 61 LMGLPGAVFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEYNNNALTLPDYFTGRFED 120 Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179 + +RI+ + I FF Y + + G ++ + FG+ + + A + YT +GG Sbjct: 121 KSRILRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATILYTFIGGF 180 Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239 +V++TDTVQA +MI LI+ P++ +I + + S+ K+ ++ +L G+ Sbjct: 181 LAVSWTDTVQASLMIFALILTPVIVIISVGG----FGDSLEVIKQKS-IENVDMLKGL-- 233 Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299 V +I+ W GY G P + RFMA + AR I + W I+ GA+ +G+ Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGF 290 Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353 GIA F + ++ E+V + LF P +A + ++ +AA++ST L++ S Sbjct: 291 FGIAYFNEHPAVAGAVNQNAERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCS 350 Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413 + +E++ K ++ K+ A ++ + V R+ + + ++A+ +A P + + +V Y WAG Sbjct: 351 SAITEDLYKAFMRKH-ASQKELVWVGRVMVLVVALVAIALA-ANPENRVLGLVSYAWAGF 408 Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453 G F +V+ ++ W R +I G L + W G Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGALTVIVWKQFG 448 >gb|AAA99290.1| (L01148) proline permease [Salmonella sp.] Length = 489 Score = 222 bits (559), Expect = 9e-57 Identities = 134/460 (29%), Positives = 229/460 (49%), Gaps = 19/460 (4%) Query: 1 MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60 M T +L Y+ +I +G R K+ D+ + GR L +V ALS A+ S W Sbjct: 1 MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60 Query: 61 LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119 L+GLPG F +G++ W AIG LG + W + AGRLR E +A+T DY R + Sbjct: 61 LMGLPGAIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFED 120 Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179 + +RI+ + I FF Y + + G ++ + FG+ + + A + YT +GG Sbjct: 121 KSRVLRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGF 180 Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239 +V++TDTVQA +MI LI+ P++ ++ + E + + ++ +L G+ Sbjct: 181 LAVSWTDTVQASLMIFALILTPVMVIVGVGGFSE-----SLEVIKQKSIENVDMLKGL-- 233 Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299 V +I+ W GY G P + RFMA + AR I + W I+ GA+ +G+ Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGF 290 Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353 GIA F N ++ E+V + LF P +A V ++ +AA++ST L++ S Sbjct: 291 FGIAYFNNNPALAGAVNQNSERVFIELAQILFNPWIAGVLLSAILAAVMSTLSCQLLVCS 350 Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413 + +E++ K ++ K+ A ++ + V R+ + + +IA+ +A P + + +V Y WAG Sbjct: 351 SAITEDLYKAFLRKS-ASQQELVWVGRVMVLVVALIAIALA-ANPDNRVLGLVTYAWAGF 408 Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453 G F +V+ ++ W R +I G + + W G Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGAVTVIVWKQYG 448 >gb|AAA99291.1| (L01149) proline permease [Salmonella sp.] Length = 489 Score = 222 bits (559), Expect = 9e-57 Identities = 134/460 (29%), Positives = 229/460 (49%), Gaps = 19/460 (4%) Query: 1 MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60 M T +L Y+ +I +G R K+ D+ + GR L +V ALS A+ S W Sbjct: 1 MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60 Query: 61 LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119 L+GLPG F +G++ W AIG LG + W + AGRLR E +A+T DY R + Sbjct: 61 LMGLPGAIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFED 120 Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179 + +RI+ + I FF Y + + G ++ + FG+ + + A + YT +GG Sbjct: 121 KSRVLRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGF 180 Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239 +V++TDTVQA +MI LI+ P++ ++ + E + + ++ +L G+ Sbjct: 181 LAVSWTDTVQASLMIFALILTPVMVIVGVGGFSE-----SLEVIKQKSIENVDMLKGL-- 233 Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299 V +I+ W GY G P + RFMA + AR I + W I+ GA+ +G+ Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGF 290 Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353 GIA F N ++ E+V + LF P +A V ++ +AA++ST L++ S Sbjct: 291 FGIAYFNNNPALAGAVNQNSERVFIELAQILFNPWIAGVLLSAILAAVMSTLSCQLLVCS 350 Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413 + +E++ K ++ K+ A ++ + V R+ + + +IA+ +A P + + +V Y WAG Sbjct: 351 SAITEDLYKAFLRKS-ASQQELVWVGRVMVLVVALIAIALA-ANPDNRVLGLVTYAWAGF 408 Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453 G F +V+ ++ W R +I G + + W G Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGAVTVIVWKQYG 448 >gb|AAA99278.1| (L01136) proline permease [Salmonella sp.] Length = 489 Score = 221 bits (558), Expect = 1e-56 Identities = 133/460 (28%), Positives = 229/460 (48%), Gaps = 19/460 (4%) Query: 1 MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60 M T +L Y+ ++ +G R K+ D+ + GR L +V ALS A+ S W Sbjct: 1 MAISTPMLVTFCVYIFGMLLIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60 Query: 61 LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119 L+GLPG F +G++ W AIG LG + W + AGRLR E +A+T DY R + Sbjct: 61 LMGLPGAIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFED 120 Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179 + +RI+ + I FF Y + + G ++ + FG+ + + A + YT +GG Sbjct: 121 KSRVLRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGF 180 Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239 +V++TDTVQA +MI LI+ P++ ++ + E + + ++ +L G+ Sbjct: 181 LAVSWTDTVQASLMIFALILTPVMVIVGVGGFSE-----SLEVIKQKSIENVDMLKGL-- 233 Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299 V +I+ W GY G P + RFMA + AR I + W I+ GA+ +G+ Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGF 290 Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353 GIA F N ++ E+V + LF P +A V ++ +AA++ST L++ S Sbjct: 291 FGIAYFNNNPALAGAVNQNSERVFIELAQILFNPWVAGVLLSAILAAVMSTLSCQLLVCS 350 Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413 + +E++ K ++ K+ A ++ + V R+ + + +IA+ +A P + + +V Y WAG Sbjct: 351 SAITEDLYKAFLRKS-ASQQELVWVGRVMVLVVALIAIALA-ANPDNRVLGLVSYAWAGF 408 Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453 G F +V+ ++ W R +I G + + W G Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGAVTVIVWKQYG 448 >gb|AAA99279.1| (L01137) proline permease [Salmonella sp.] Length = 489 Score = 221 bits (558), Expect = 1e-56 Identities = 133/460 (28%), Positives = 229/460 (48%), Gaps = 19/460 (4%) Query: 1 MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60 M T +L Y+ ++ +G R K+ D+ + GR L +V ALS A+ S W Sbjct: 1 MAISTPMLVTFCVYIFGMLLIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60 Query: 61 LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119 L+GLPG F +G++ W AIG LG + W + AGRLR E +A+T DY R + Sbjct: 61 LMGLPGAIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFED 120 Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179 + +RI+ + I FF Y + + G ++ + FG+ + + A + YT +GG Sbjct: 121 KSRVLRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGF 180 Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239 +V++TDTVQA +MI LI+ P++ ++ + E + + ++ +L G+ Sbjct: 181 LAVSWTDTVQASLMIFALILTPVMVIVGVGGFSE-----SLEVIKQKSIENVDMLKGL-- 233 Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299 V +I+ W GY G P + RFMA + AR I + W I+ GA+ +G+ Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGF 290 Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353 GIA F N ++ E+V + LF P +A V ++ +AA++ST L++ S Sbjct: 291 FGIAYFNNNPALAGAVNQNSERVFIELAQILFNPWVAGVLLSAILAAVMSTLSCQLLVCS 350 Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413 + +E++ K ++ K+ A ++ + V R+ + + +IA+ +A P + + +V Y WAG Sbjct: 351 SAITEDLYKAFLRKS-ASQQELVWVGRVMVLVVALIAIALA-ANPDNRVLGLVSYAWAGF 408 Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453 G F +V+ ++ W R +I G + + W G Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGAVTVIVWKQYG 448 >gb|AAA24465.1| (L01152) proline permease [Escherichia coli] Length = 489 Score = 221 bits (557), Expect = 2e-56 Identities = 133/460 (28%), Positives = 230/460 (49%), Gaps = 19/460 (4%) Query: 1 MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60 M T +L Y+ +I +G R K+ D+ + GR L +V ALS A+ S W Sbjct: 1 MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60 Query: 61 LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119 L+GLPG F +G++ W AIG LG + W + AGRLR E +A+T DY R + Sbjct: 61 LMGLPGAVFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEYNNNALTLPDYFTGRFED 120 Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179 + +RI+ + I FF Y + + G ++ + FG+ + + + YT +GG Sbjct: 121 KSRILRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGVAATILYTFIGGF 180 Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239 +V++TDTVQA +MI LI+ P++ +I + + S+ K+ ++ +L G+ Sbjct: 181 LAVSWTDTVQASLMIFALILTPVIVIISVGG----FGDSLEVIKQKS-IENVDMLKGL-- 233 Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299 V +I+ W GY G P + RFMA + AR I + W I+ GA+ +G+ Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGF 290 Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353 GIA F + ++ E+V + LF P +A + ++ +AA++ST L++ S Sbjct: 291 FGIAYFNEHPAVAGAVNQNAERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCS 350 Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413 + +E++ K ++ K+ A ++ + V R+ + + ++A+ +A P + + +V Y WAG Sbjct: 351 SAITEDLYKAFLRKH-ASQKELVWVGRVMVLVVALVAIALA-ANPENRVLGLVSYAWAGF 408 Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453 G F +V+ ++ W R +I G L + W G Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGALTVIVWKQFG 448 >gb|AAA99281.1| (L01139) proline permease [Salmonella sp.] Length = 489 Score = 221 bits (557), Expect = 2e-56 Identities = 132/460 (28%), Positives = 229/460 (49%), Gaps = 19/460 (4%) Query: 1 MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60 M T +L Y+ ++ +G R K+ D+ + GR L +V ALS A+ S W Sbjct: 1 MAISTPMLVTFCVYILGMLLIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60 Query: 61 LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119 L+GLPG F +G++ W AIG LG + W + AGRLR E +A+T DY R + Sbjct: 61 LMGLPGAIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFED 120 Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179 + +RI+ + I FF Y + + G ++ + FG+ + + A + YT +GG Sbjct: 121 KSRVLRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGF 180 Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239 +V++TDTVQA +MI LI+ P++ ++ + E + + ++ +L G+ Sbjct: 181 LAVSWTDTVQASLMIFALILTPVMVIVGVGGFSE-----SLEVIKQKSIENVDMLKGL-- 233 Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299 V +I+ W GY G P + RFMA + AR I + W I+ GA+ +G+ Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGF 290 Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353 GIA F N ++ E+V + LF P +A + ++ +AA++ST L++ S Sbjct: 291 FGIAYFNNNPALAGAVNQNSERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCS 350 Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413 + +E++ K ++ K+ A ++ + V R+ + + +IA+ +A P + + +V Y WAG Sbjct: 351 SAITEDLYKAFLRKS-ASQQELVWVGRVMVLVVALIAIALA-ANPDNRVLGLVSYAWAGF 408 Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453 G F +V+ ++ W R +I G + + W G Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGAVTVIVWKQYG 448 >gb|AAA99280.1| (L01138) proline permease [Salmonella sp.] Length = 489 Score = 220 bits (556), Expect = 2e-56 Identities = 132/460 (28%), Positives = 229/460 (49%), Gaps = 19/460 (4%) Query: 1 MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60 M T +L Y+ ++ +G R K+ D+ + GR L +V ALS A+ S W Sbjct: 1 MAISTPMLVTFCVYILGMLLIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60 Query: 61 LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119 L+GLPG F +G++ W AIG LG + W + AGRLR E +A+T DY R + Sbjct: 61 LMGLPGAIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFED 120 Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179 + +RI+ + I FF Y + + G ++ + FG+ + + A + YT +GG Sbjct: 121 KSRVLRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGF 180 Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239 +V++TDTVQA +MI LI+ P++ ++ + E + + ++ +L G+ Sbjct: 181 LAVSWTDTVQASLMIFALILTPVMVIVGVGGFSE-----SLEVIKQKSIENVDMLKGL-- 233 Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299 V +I+ W GY G P + RFMA + AR I + W I+ GA+ +G+ Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHYSIVHARRISMTWMILCLAGAVAVGF 290 Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353 GIA F N ++ E+V + LF P +A + ++ +AA++ST L++ S Sbjct: 291 FGIAYFNNNPALAGAVNQNSERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCS 350 Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413 + +E++ K ++ K+ A ++ + V R+ + + +IA+ +A P + + +V Y WAG Sbjct: 351 SAITEDLYKAFLRKS-ASQQELVWVGRVMVLVVALIAIALA-ANPDNRVLGLVSYAWAGF 408 Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453 G F +V+ ++ W R +I G + + W G Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGAVTVIVWKQYG 448 >gb|AAA99284.1| (L01142) proline permease [Salmonella sp.] >gi|154306|gb|AAA99285.1| (L01143) proline permease [Salmonella sp.] Length = 489 Score = 220 bits (556), Expect = 2e-56 Identities = 132/460 (28%), Positives = 229/460 (49%), Gaps = 19/460 (4%) Query: 1 MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60 M T +L Y+ ++ +G R K+ D+ + GR L +V ALS A+ S W Sbjct: 1 MAISTPMLVTFCVYILGMLLIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60 Query: 61 LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119 L+GLPG F +G++ W AIG LG + W + AGRLR E +A+T DY R + Sbjct: 61 LMGLPGAIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFED 120 Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179 + +RI+ + I FF Y + + G ++ + FG+ + + A + YT +GG Sbjct: 121 KSRVLRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGF 180 Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239 +V++TDTVQA +MI LI+ P++ ++ + E + + ++ +L G+ Sbjct: 181 LAVSWTDTVQASLMIFALILTPVMVIVGVGGFSE-----SLEVIKQKSIENVDMLKGL-- 233 Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299 V +I+ W GY G P + RFMA + AR I + W I+ GA+ +G+ Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGF 290 Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353 GIA F N ++ E+V + LF P +A V ++ +AA++ST L++ S Sbjct: 291 FGIAYFNNNPALAGAVNQNSERVFIELAQILFNPWVAGVLLSAILAAVMSTLSCQLLVCS 350 Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413 + +E++ K ++ K+ A ++ + V R+ + + ++A+ +A P + + +V Y WAG Sbjct: 351 SAITEDLYKAFLRKS-ASQQELVWVGRVMVLVVALVAIALA-ANPDNRVLGLVSYAWAGF 408 Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453 G F +V+ ++ W R +I G + + W G Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGAVTVIVWKQYG 448 >gb|AAA99286.1| (L01144) proline permease [Salmonella sp.] >gi|154310|gb|AAA99287.1| (L01145) proline permease [Salmonella sp.] Length = 489 Score = 220 bits (556), Expect = 2e-56 Identities = 131/460 (28%), Positives = 229/460 (49%), Gaps = 19/460 (4%) Query: 1 MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60 M T +L Y+ ++ +G R K+ D+ + GR L +V ALS A+ S W Sbjct: 1 MAISTPMLVTFCVYILGMLLIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60 Query: 61 LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPE 119 L+GLPG F +G++ W AIG LG + W + AGRLR E +A+T DY R + Sbjct: 61 LMGLPGAIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFED 120 Query: 120 AEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGL 179 + +RI+ + I FF Y + + G ++ + FG+ + + A + YT +GG Sbjct: 121 KSRVLRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGF 180 Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239 +V++TDTVQA +MI LI+ P++ ++ + E + + ++ +L G+ Sbjct: 181 LAVSWTDTVQASLMIFALILTPVMVIVGVGGFSE-----SLEVIKQKSIENVDMLKGL-- 233 Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299 V +I+ W GY G P + RFMA + AR I + W I+ GA+ +G+ Sbjct: 234 --NFVAIISLMGWGLGYF-GQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGF 290 Query: 300 IGIAIFGPNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353 GIA F N ++ E+V + LF P +A + ++ +AA++ST L++ S Sbjct: 291 FGIAYFNNNPALAGAVNQNSERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCS 350 Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413 + +E++ K ++ K+ A ++ + V R+ + + ++A+ +A P + + +V Y WAG Sbjct: 351 SAITEDLYKAFLRKS-ASQQELVWVGRVMVLVVALVAIALA-ANPDNRVLGLVSYAWAGF 408 Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453 G F +V+ ++ W R +I G + + W G Sbjct: 409 GAAFGPVVLFSVMWSRMTRNGALAGMIIGAVTVIVWKQYG 448 >gb|AAF25001.1|AF153207_2 (AF153207) proline permease [Pseudomonas putida] >gi|8132050|gb|AAF73192.1|AF151964_1 (AF151964) proline permease [Pseudomonas putida] Length = 492 Score = 215 bits (543), Expect = 7e-55 Identities = 134/446 (30%), Positives = 220/446 (49%), Gaps = 21/446 (4%) Query: 12 VFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGFAFAA 71 V Y+ ++ +G R + D+ + GR L V ALS A+ S W L+GLPG + A Sbjct: 10 VIYIAAMVLIGFAAYRATNNLSDYILGGRSLGSVVTALSAGASDMSGWLLMGLPGAIYFA 69 Query: 72 GLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKY-DAVTFVDYIAKRHPEAEKWIRILGSA 130 GL+ W AIG +G + W AGRLR + E DA+T DY + R + +RI+ + Sbjct: 70 GLSEAWIAIGLTVGAYLNWLFVAGRLRVQTEHNGDALTLPDYFSSRFEDNSGLLRIISAI 129 Query: 131 TIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTDTVQA 190 I FF Y + + G ++ + FG+ + + A + YT +GG +V++TDTVQA Sbjct: 130 VILVFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIAYTFVGGFLAVSWTDTVQA 189 Query: 191 IVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAAIVFVIAEF 250 +MI LI+ P++ +I + + AA+ + +L G A + +I+ Sbjct: 190 SLMIFALILTPVIVLISTGGFDQTF-----AAIEAVNRRNFDMLKG----ATFIGIISLM 240 Query: 251 SWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGWIGIAIF----- 305 W GY P + RFMA + AR I + W I+ G +G+ GIA F Sbjct: 241 GWGLGYF-RPPHILARFMAADSVNSIAKARRISMTWMILCLAGTCAVGFCGIAYFSAHPE 299 Query: 306 --GPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSENILKP 363 GP ++ ++V + LF P +A V ++ +AA++ T L++ S+ +EN K Sbjct: 300 LAGPVS-ENHKRVFIELAKILFNPWVAGVLLSAILAAVMITLSCQLLVCSSALTENFYKA 358 Query: 364 YIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVIVIL 423 ++ KN A + + V RL +++ +IA+ MA P + + +V Y WAG G F +V++ Sbjct: 359 FLRKN-ASQVELVWVGRLMVLAVALIAIAMA-ANPENRVLGLVAYAWAGFGAAFGPVVLI 416 Query: 424 TLFWKRFHGKAVPPTIIAGLLFTVFW 449 ++ WK I+ G L + W Sbjct: 417 SVLWKGMTRNGALAGIVVGALTVILW 442 >gb|AAG19342.1| (AE005029) proline permease; PutP [Halobacterium sp. NRC-1] Length = 522 Score = 210 bits (530), Expect = 2e-53 Identities = 127/421 (30%), Positives = 218/421 (51%), Gaps = 19/421 (4%) Query: 34 DFSIAGRQLPGWVAALSERATGESAWCLLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVF 93 D+ I GR + V SERA+ S W LG+PG A+ G+ A + +G + + AWA Sbjct: 6 DYVIGGRDVGPVVTGFSERASEMSGWLTLGVPGDAYTTGIMAFYNGVGMIPADLAAWAGL 65 Query: 94 AGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNT 153 A RLRK +E AVT + A R + ++ + S + F YVGAQ + G +L Sbjct: 66 AKRLRKYSEIVRAVTLPTFFATRLNDDTGVVKAVSSFVLIVFEGSYVGAQIVAAGTLLRV 125 Query: 154 LFGLDPKLGMLITALVILPYTVMGGLKSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPE 213 L G+D +G++ ++++ YT++GG +VA++D Q +++ + PI+ Sbjct: 126 LTGVDMWVGIVAGGVIVVGYTMLGGYFAVAWSDYFQGAIILAAFAILPIIA--------- 176 Query: 214 LYAT----SVTAALSKAGVKYSTILGGMAGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMA 269 YAT A G ++I GG G AA+ +I+ + G + G P + +RFM Sbjct: 177 -YATWGLPFADLAAMDNGASLTSITGGATGWAALFGIISYAAVGLG-IPGNPHIMVRFMG 234 Query: 270 IKDDKNAKLARNIGIGWTIIAYIGALMIGWIGIAIFGPNGLKDPEQVMPSVMLKLFPPAL 329 I +N + A + + +AYIGA ++G + FG GL++ + MP V L+L P A+ Sbjct: 235 IDRVRNVRTAAVVAQLFMFVAYIGAALVGLYALTQFG--GLENTDNAMPLVTLELLPSAV 292 Query: 330 AAVFITGAVAAMLSTADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGII 389 A V + A+AAM+S+ADS L+++++ E++ ++ +A + + SR T+++G Sbjct: 293 AGVVLAAALAAMMSSADSQLLVATSAVVEDVYHGFL-NEQATEAQLVRYSRYVTLAIGFA 351 Query: 390 ALIMAYVVPSHLIYTIV-GYTWAGIGDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVF 448 ++ AYV + IY +V Y W G+G ++I L+W+R +++ G + Sbjct: 352 SIGFAYVARNTPIYELVLNYAWGGLGAALGPLLIAVLWWRRVTAAGAVASMVTGTATMIL 411 Query: 449 W 449 W Sbjct: 412 W 412 >dbj|BAB06425.1| (AP001516) proline transporter [Bacillus halodurans] Length = 507 Score = 208 bits (525), Expect = 9e-53 Identities = 140/449 (31%), Positives = 227/449 (50%), Gaps = 25/449 (5%) Query: 8 LAVLVFYLGFLISVGIYQGRKAK-SHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPG 66 +A+L+ YL L+ +G+ +K+ DF IAGR L W ALS ++G SAW +LG+ G Sbjct: 9 VAILIAYLVALLLIGLLSSKKSSVGMTDFFIAGRNLNKWTVALSAVSSGRSAWLVLGVTG 68 Query: 67 FAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRI 126 A+A GL A+W G + + + A R R +E+ ++T D + R + +R Sbjct: 69 TAYATGLDAVWAVAGYITVEVFLFFYVARRFRAYSEQTGSITIPDILETRFNDKTHILRG 128 Query: 127 LGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTD 186 + I FF YV +Q + GG T G+ GM +TA+++L YT++GG +V+ TD Sbjct: 129 GSAFIIMFFMIAYVASQLVAGGGAFATSMGVSSSTGMWVTAVILLAYTMLGGFHAVSKTD 188 Query: 187 TVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAAIVF- 245 VQA M ++L++ P+V +I + L T GG A F Sbjct: 189 VVQAGFMFVSLVILPVVAIIGLGGFDPLLQVMHTEG------------GGFTSPFAFGFG 236 Query: 246 -VIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGWIGIAI 304 VI FG G P + +R+M++K+ K + A I W ++ GA+MIG G A Sbjct: 237 AVIGLLGIGFGSPGN-PHILVRYMSLKNVKEMRQAALISSVWNVLMGWGAVMIGLAGRAY 295 Query: 305 FG-----PNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSEN 359 F PNG D EQV + ++ P + +AA++S+ADS L++ S+ F + Sbjct: 296 FPDVSLLPNG--DQEQVFLMLGSEILHPLFFGFLLVAVLAAIMSSADSQLLVGSSAFVRD 353 Query: 360 ILKPYIYKNEADPRKSLM-VSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFS 418 I + +N +K L+ +SRLTTV ++LI+A+ ++ +V + + G+G F Sbjct: 354 IYQKMFRRNRKLSQKKLVRLSRLTTVVFMGLSLILAFTA-QEFVFWMVLFAFGGLGACFG 412 Query: 419 VIVILTLFWKRFHGKAVPPTIIAGLLFTV 447 ++L+ +WK + V +IAGLL + Sbjct: 413 PALLLSFYWKGVTRQGVLWGMIAGLLTVI 441 >sp|P45174|PUTP_HAEIN SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE) >gi|1075316|pir||E64118 sodium/proline symporter - Haemophilus influenzae (strain Rd KW20) >gi|1574814|gb|AAC22999.1| (U32814) sodium/proline symporter (proline permease) (putP) [Haemophilus influenzae Rd] Length = 504 Score = 207 bits (522), Expect = 2e-52 Identities = 131/488 (26%), Positives = 238/488 (47%), Gaps = 20/488 (4%) Query: 8 LAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGF 67 L Y+ ++ +G+ + D+ + GR+L +V A+S A+ S W L+GLPG Sbjct: 8 LITFTIYIFGMLLIGVLAYYYTNNLSDYILGGRRLGSFVTAMSAGASDMSGWLLMGLPGA 67 Query: 68 AFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKRHPEAEKWIRI 126 + +GL W AIG +G W + AGRLR E +A+T +Y R + K +++ Sbjct: 68 VYLSGLVEGWIAIGLTIGAYFNWLLVAGRLRVYTELNNNALTLPEYFHNRFGSSHKLLKL 127 Query: 127 LGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTD 186 + + I F Y + + G K+ +F ++ + A + YT +GG +V++TD Sbjct: 128 VSATIILVFLTIYCASGVVAGAKLFQNIFSVEYSTALWYGAAATIAYTFIGGFLAVSWTD 187 Query: 187 TVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAAIVFV 246 T+QA +MI LI+ P+ ++ A+ +A L +A + + + + + Sbjct: 188 TIQATLMIFALILTPVFVLLSFAD-----TAQFSAVLEQAEAAVNKDFTDLFTSTTPLGL 242 Query: 247 IAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGWIGIAIFG 306 ++ +W GY G P + RFMA K+ AR I +GW ++ GA+ IG I F Sbjct: 243 LSLAAWGLGYF-GQPHILARFMAADSVKSLIKARRISMGWMVLCLAGAIGIGLFAIPYFF 301 Query: 307 PNGL------KDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSENI 360 N ++PEQV + LF P +A + ++ +AA++ST + L++SS+ +E+ Sbjct: 302 ANPAIAGTVNREPEQVFIELAKLLFNPWIAGILLSAILAAVMSTLSAQLLISSSSITEDF 361 Query: 361 LKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVI 420 K +I N A ++ + + R+ + + +A+ +A S ++ +V + WAG G F + Sbjct: 362 YKGFIRPN-ASEKELVWLGRIMVLVIAALAIWIAQDENSKVL-KLVEFAWAGFGSAFGPV 419 Query: 421 VILTLFWKRFHGKAVPPTIIAGLLFTVFW---ISSGLD-AKVSVRLMNF-IVTFIVAIIA 475 V+ +LFWKR ++ G + W + + D KV + F + + +I+ Sbjct: 420 VLFSLFWKRMTSSGAMAGMLVGAVTVFAWKEVVPADTDWFKVYEMIPGFAFASLAIIVIS 479 Query: 476 TYAIKPEK 483 + KPE+ Sbjct: 480 LLSNKPEQ 487 >gi|11498674 pantothenate permease (panF-1) [Archaeoglobus fulgidus] >gi|7442768|pir||E69383 pantothenate permease (panF-1) homolog - Archaeoglobus fulgidus >gi|2649519|gb|AAB90171.1| (AE001029) pantothenate permease (panF-1) [Archaeoglobus fulgidus] Length = 491 Score = 170 bits (426), Expect = 4e-41 Identities = 133/461 (28%), Positives = 231/461 (49%), Gaps = 29/461 (6%) Query: 7 ILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPG 66 I AVL+ YL ++ +GIY+ RK + D+ +AG++L V + S AT S LG G Sbjct: 3 IEAVLIGYLAVVLLIGIYEYRKTRGLLDYYLAGKKLGTLVVSFSFFATYFSTAAFLGGGG 62 Query: 67 FAFAAGLAAIWPAIGC---VLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKW 123 F G W A VL I+AW V A +++ A++Y A+T + KR A + Sbjct: 63 TGFLLGFQ--WSAFLTFFHVLFAILAWMVIAPPMKRIADEYGALTIPELFRKR---AGVF 117 Query: 124 IRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVA 183 +I+ + I FFF Y+ + Y G G +L + +D G++ITA++++ YT +GG ++V Sbjct: 118 SQIVAAVVIIFFFELYMVSIYKGAGNLLQVMLSMDYTTGLVITAVIVMVYTAIGGFRAVV 177 Query: 184 YTDTVQAIVMI-------LTLI--VAPIVGVIYIANHPELYATSVTAALSKAGVKYSTIL 234 TD +Q ++++ LTLI + I ++ +++ V AL + G K Sbjct: 178 MTDLIQGVIVLIGGVALFLTLIYSLGGFSSAIEALSNAKIFGEMVGKALFEIG-KVGPPP 236 Query: 235 GGMAGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDK---NAKLARNIGIGWTIIAY 291 AG + F+ L PQL +RF+A +D + N + + IG I Sbjct: 237 IVKAGMIVPFVLSLTFAISVAQLAS-PQLVVRFVAARDSRVIANGMILTPLIIGIFAICV 295 Query: 292 IGALMIGWIGIAIFGPN---GLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSL 348 GW+ I + + LKD + V+P + +KLFP + A+ +T +AA +ST +SL Sbjct: 296 FSIGPFGWLVIPKYTDDVTQFLKDVDLVVPFIAMKLFPAGINALLLTAIIAAAMSTINSL 355 Query: 349 LILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGY 408 + L +T F ++++ + + R +L ++R I +I A + P +I IVG Sbjct: 356 IHLVATAFVRDLVQNV---KKIEERTALNLTRFAVFIFATIPVIFA-INPMGVIVEIVGV 411 Query: 409 TWAGIGDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFW 449 +++ I F V +I L+ ++ + A+ +++A +L +V W Sbjct: 412 SFSVITSAFLVPLIACLYSEKPNSAAISASMVAAVLASVLW 452 >sp|P44963|PANF_HAEIN SODIUM/PANTOTHENATE SYMPORTER (PANTOTHENATE PERMEASE) >gi|1075105|pir||H64105 pantothenate transport protein - Haemophilus influenzae (strain Rd KW20) >gi|1574003|gb|AAC22634.1| (U32778) sodium/pantothenate symporter (panF) [Haemophilus influenzae Rd] Length = 484 Score = 152 bits (379), Expect = 1e-35 Identities = 128/467 (27%), Positives = 223/467 (47%), Gaps = 30/467 (6%) Query: 7 ILAVLVFYLGFLISVGIY---QGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLG 63 I+ L+ YL F+ I+ + K ++ + R + G+V A++ +T SA +G Sbjct: 5 IILPLIIYLTFVFGAAIFAYVKRTKGDFLTEYYVGNRSMTGFVLAMTTASTYASASSFVG 64 Query: 64 LPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKW 123 PG A+ GL + A+ V + +A + + + +A+T D R+ K+ Sbjct: 65 GPGAAYKYGLGWVLLAMIQVPVVWLALGALGKKFALLSRETNALTINDLFFYRYKN--KY 122 Query: 124 IRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVA 183 + L S + FF + Q++GG ++L T G+ +L+ AL + YT +GG ++V Sbjct: 123 LVWLSSLALLLAFFAAMTVQFIGGARLLETTIGISYTQALLLFALTVGIYTFIGGFRAVV 182 Query: 184 YTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAAI 243 TDT+Q VMI I+ ++G IY E +T Y G G Sbjct: 183 LTDTIQGTVMIFGTIIL-LIGTIYALGGVESAVNKLTEIDPDLVTPY-----GPNGMLDF 236 Query: 244 VFVIAEFSWFFGYLG--GMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGWIG 301 F +A F W G G+P ++R MA KD K IG I +G + G +G Sbjct: 237 QF-MASF-WILVCFGVVGLPHTAVRCMAFKDSKALHRGMLIGTIVLSIIMLGMHLAGALG 294 Query: 302 IAIFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSENI- 360 A+ PN L +QV+P++M+K+ PP +A +F+ ++A++ST D+ LI SS+ F +++ Sbjct: 295 RAVI-PN-LTVSDQVIPTLMIKVLPPIVAGIFLAAPMSAIMSTIDAQLIQSSSIFVKDLY 352 Query: 361 --LKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFS 418 KP KNE +K S + T+ L + LI A + P +I + + + G+ F Sbjct: 353 LSAKPEAAKNE---KKVSYFSSIITLILTAL-LIFAALNPPDMIIWLNLFAFGGLEAAFL 408 Query: 419 VIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSGLDAKVSVRLMNF 465 +++L ++W + + ++I GL + L ++ ++L NF Sbjct: 409 WVIVLGIYWDKANAYGALSSMIIGLGSYI------LLTQLGIKLFNF 449 >pir||D65118 pantothenate permease [validated] - Escherichia coli >gi|606198|gb|AAA58061.1| (U18997) pantothenate permease [Escherichia coli] >gi|1789656|gb|AAC76290.1| (AE000404) sodium/pantothenate symporter [Escherichia coli K12] Length = 485 Score = 144 bits (360), Expect = 2e-33 Identities = 123/463 (26%), Positives = 233/463 (49%), Gaps = 39/463 (8%) Query: 1 MEARTQILAVLVFYLGFLISVGIYQGRKAKSH---KDFSIAGRQLPGWVAALSERATGES 57 M + +++ LV YL + + +Y RK + ++ + R + G V A++ AT S Sbjct: 1 MTMQLEVILPLVAYLVVVFGISVYAMRKRSTGTFLNEYFLGSRSMGGIVLAMTLTATYIS 60 Query: 58 AWCLLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRH 117 A +G PG A+ GL + A+ + + ++ + + A +Y+AVT D + R+ Sbjct: 61 ASSFIGGPGAAYKYGLGWVLLAMIQLPAVWLSLGILGKKFAILARRYNAVTLNDMLFARY 120 Query: 118 PEAEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMG 177 + + L S ++ F + Q++GG ++L T G+ + G+LI + I YT G Sbjct: 121 QS--RLLVWLASLSLLVAFVGAMTVQFIGGARLLETAAGIPYETGLLIFGISIALYTAFG 178 Query: 178 GLKSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTI---L 234 G ++ DT+Q +VM++ +V ++GV++ A LS A TI L Sbjct: 179 GFRASVLNDTMQGLVMLIGTVVL-LIGVVHAA-----------GGLSNAVQTLQTIDPQL 226 Query: 235 GGMAGAAAIVFVIAEFSWF----FGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIA 290 GA I+ S++ FG + G+P ++R ++ KD K + R I IG ++A Sbjct: 227 VTPQGADDILSPAFMTSFWVLVCFGVI-GLPHTAVRCISYKDSK--AVHRGIIIGTIVVA 283 Query: 291 YI--GALMIGWIGIAIFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSL 348 + G + G +G A+ L P+ V+P++M+K+ PP A +F+ +AA++ST ++ Sbjct: 284 ILMFGMHLAGALGRAVI--PDLTVPDLVIPTLMVKVLPPFAAGIFLAAPMAAIMSTINAQ 341 Query: 349 LILSSTEFSENI---LKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTI 405 L+ SS +++ ++P +NE ++ +S + T+ LG + L+ A+ P +I+ Sbjct: 342 LLQSSATIIKDLYLNIRPDQMQNETRLKR---MSAVITLVLGALLLLAAWKPPEMIIWLN 398 Query: 406 VGYTWAGIGDTFSVIVILTLFWKRFHGK-AVPPTIIAGLLFTV 447 + + G+ F ++L L+W+R + K A+ I+ G+L+ V Sbjct: 399 L-LAFGGLEAVFLWPLVLGLYWERANAKGALSAMIVGGVLYAV 440 >sp|P16256|PANF_ECOLI SODIUM/PANTOTHENATE SYMPORTER (PANTOTHENATE PERMEASE) Length = 483 Score = 143 bits (357), Expect = 4e-33 Identities = 122/458 (26%), Positives = 231/458 (49%), Gaps = 39/458 (8%) Query: 6 QILAVLVFYLGFLISVGIYQGRKAKSH---KDFSIAGRQLPGWVAALSERATGESAWCLL 62 +++ LV YL + + +Y RK + ++ + R + G V A++ AT SA + Sbjct: 4 EVILPLVAYLVVVFGISVYAMRKRSTGTFLNEYFLGSRSMGGIVLAMTLTATYISASSFI 63 Query: 63 GLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEK 122 G PG A+ GL + A+ + + ++ + + A +Y+AVT D + R+ + Sbjct: 64 GGPGAAYKYGLGWVLLAMIQLPAVWLSLGILGKKFAILARRYNAVTLNDMLFARYQS--R 121 Query: 123 WIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSV 182 + L S ++ F + Q++GG ++L T G+ + G+LI + I YT GG ++ Sbjct: 122 LLVWLASLSLLVAFVGAMTVQFIGGARLLETAAGIPYETGLLIFGISIALYTAFGGFRAS 181 Query: 183 AYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTI---LGGMAG 239 DT+Q +VM++ +V ++GV++ A LS A TI L G Sbjct: 182 VLNDTMQGLVMLIGTVVL-LIGVVHAA-----------GGLSNAVQTLQTIDPQLVTPQG 229 Query: 240 AAAIVFVIAEFSWF----FGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYI--G 293 A I+ S++ FG + G+P ++R ++ KD K + R I IG ++A + G Sbjct: 230 ADDILSPAFMTSFWVLVCFGVI-GLPHTAVRCISYKDSK--AVHRGIIIGTIVVAILMFG 286 Query: 294 ALMIGWIGIAIFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353 + G +G A+ L P+ V+P++M+K+ PP A +F+ +AA++ST ++ L+ SS Sbjct: 287 MHLAGALGRAVI--PDLTVPDLVIPTLMVKVLPPFAAGIFLAAPMAAIMSTINAQLLQSS 344 Query: 354 TEFSENI---LKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTW 410 +++ ++P +NE ++ +S + T+ LG + L+ A+ P +I+ + + Sbjct: 345 ATIIKDLYLNIRPDQMQNETRLKR---MSAVITLVLGALLLLAAWKPPEMIIWLNL-LAF 400 Query: 411 AGIGDTFSVIVILTLFWKRFHGK-AVPPTIIAGLLFTV 447 G+ F ++L L+W+R + K A+ I+ G+L+ V Sbjct: 401 GGLEAVFLWPLVLGLYWERANAKGALSAMIVGGVLYAV 438 >pir||C69115 sodium/proline symporter (proline permease) - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622992|gb|AAB86322.1| (AE000938) sodium/proline symporter (proline permease) [Methanobacterium thermoautotrophicum] Length = 526 Score = 137 bits (342), Expect = 3e-31 Identities = 106/468 (22%), Positives = 216/468 (45%), Gaps = 41/468 (8%) Query: 8 LAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGF 67 + VL+++L + VG R+ ++ +D+ +AGR+ ++ A+S AT S ++G G Sbjct: 8 IVVLIYFL-LVGYVGYVAWRRTETSEDYMVAGRRTHPYIMAMSYGATFISTAAIVGFGGM 66 Query: 68 AFAAGLAAIWPA-IGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRI 126 A G+ +W + ++GI +A+ F R K A+TF +++ +R ++++ Sbjct: 67 AGVFGMGILWLVFLNILVGIFIAFVFFGKRTMKMGHNMSALTFPEFLGRRFNS--RFLQY 124 Query: 127 LGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTD 186 G A I Y +G + + T GLD + +++ A+++ Y V+GG++ V YTD Sbjct: 125 FGGAIIFLGMPLYASVVLIGAARFIETTLGLDFSIALILMAVIVAVYVVLGGIRGVMYTD 184 Query: 187 TVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAAIVFV 246 +Q +M L +I +V Y+ ++T K I G G ++ Sbjct: 185 ALQGTIMFLGMIFL-VVSTYYLLGGVVDAHQALTNISHLIPAKARAI--GATGWTSMPLY 241 Query: 247 IAEFSWFF----------GYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTII------A 290 + + W G L PQL +RFM +K N +L R + IG I A Sbjct: 242 GSPYWWTLLSTIILGVGVGVLA-QPQLIVRFMTVKS--NRELNRGVLIGALFIFVMTWSA 298 Query: 291 YI-GALM-------IGWIGIAIFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAML 342 Y+ GAL +G I + G N ++++P + P + +F+ ++A + Sbjct: 299 YVVGALSNVYFFRKMGMIAVQAAGGNA----DKIIPFFIKSAMPEWFSYIFMLTLLSAAM 354 Query: 343 STADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLI 402 ST + + T ++ + + + + D +S++++R + +IA+++ Y++P ++ Sbjct: 355 STLSAQFHVQGTAIGRDVYET-VRRRKGD--RSVLITRGGIIIAVLIAVVLGYLLPGSIV 411 Query: 403 YTIVGYTWAGIGDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWI 450 + +F + + +FWKR + +++G + ++FW+ Sbjct: 412 AQGTALFFGICAASFLSVYVAAIFWKRATRQGAIAGMVSGAIVSLFWL 459 >gb|AAF45280.1| (AF230619) proline permease [Escherichia coli] Length = 232 Score = 135 bits (336), Expect = 1e-30 Identities = 79/239 (33%), Positives = 125/239 (52%), Gaps = 11/239 (4%) Query: 32 HKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGFAFAAGLAAIWPAIGCVLGIIVAWA 91 H D+ + GR L +V ALS A+ S W L+GLPG F +G++ W AIG LG + W Sbjct: 1 HDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGAVFLSGISESWIAIGLTLGAWINWK 60 Query: 92 VFAGRLRKEAE-KYDAVTFVDYIAKRHPEAEKWIRILGSATIAFFFFFYVGAQYLGGGKV 150 + AGRLR E +A+T DY R + + +RI+ + I FF Y + + G ++ Sbjct: 61 LVAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARL 120 Query: 151 LNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTDTVQAIVMILTLIVAPIVGVIYIAN 210 + FG+ + + A + YT +GG +V++TDTVQA +MI LI+ P++ +I + Sbjct: 121 FESTFGMSYETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGG 180 Query: 211 HPELYATSVTAALSKAGVKYSTILGGMAGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMA 269 + S+ K+ ++ +L G+ V +I+ W GY G P + RFMA Sbjct: 181 ----FGDSLEVIKQKS-IENVDMLKGL----NFVAIISLMGWGLGYF-GQPHILARFMA 229 >gb|AAF45283.1| (AF230622) proline permease [Escherichia coli] Length = 232 Score = 132 bits (330), Expect = 6e-30 Identities = 78/239 (32%), Positives = 125/239 (51%), Gaps = 11/239 (4%) Query: 32 HKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGFAFAAGLAAIWPAIGCVLGIIVAWA 91 + D+ + GR L +V ALS A+ S W L+GLPG F +G++ W AIG LG + W Sbjct: 1 YDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGAVFLSGISESWIAIGLTLGAWINWK 60 Query: 92 VFAGRLRKEAE-KYDAVTFVDYIAKRHPEAEKWIRILGSATIAFFFFFYVGAQYLGGGKV 150 + AGRLR E +A+T DY R + + +RI+ + I FF Y + + G ++ Sbjct: 61 LVAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARL 120 Query: 151 LNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTDTVQAIVMILTLIVAPIVGVIYIAN 210 + FG+ + + A + YT +GG +V++TDTVQA +MI LI+ P++ +I + Sbjct: 121 FESTFGMSYETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGG 180 Query: 211 HPELYATSVTAALSKAGVKYSTILGGMAGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMA 269 + S+ K+ ++ +L G+ V +I+ W GY G P + RFMA Sbjct: 181 ----FGDSLEVIKQKS-IENVDMLKGL----NFVAIISLMGWGLGYF-GQPHILARFMA 229 >gb|AAF45263.1| (AF230602) proline permease [Escherichia coli] >gi|7288753|gb|AAF45265.1| (AF230604) proline permease [Escherichia coli] >gi|7288757|gb|AAF45267.1| (AF230606) proline permease [Escherichia coli] >gi|7288765|gb|AAF45271.1| (AF230610) proline permease [Escherichia coli] >gi|7288769|gb|AAF45273.1| (AF230612) proline permease [Escherichia coli] >gi|7288771|gb|AAF45274.1| (AF230613) proline permease [Escherichia coli] >gi|7288773|gb|AAF45275.1| (AF230614) proline permease [Escherichia coli] >gi|7288775|gb|AAF45276.1| (AF230615) proline permease [Escherichia coli] >gi|7288777|gb|AAF45277.1| (AF230616) proline permease [Escherichia coli] >gi|7288779|gb|AAF45278.1| (AF230617) proline permease [Escherichia coli] >gi|7288781|gb|AAF45279.1| (AF230618) proline permease [Escherichia coli] >gi|7288785|gb|AAF45281.1| (AF230620) proline permease [Escherichia coli] >gi|7288787|gb|AAF45282.1| (AF230621) proline permease [Escherichia coli] >gi|7288791|gb|AAF45284.1| (AF230623) proline permease [Escherichia coli] >gi|7288797|gb|AAF45287.1| (AF230626) proline permease [Escherichia coli] >gi|7288799|gb|AAF45288.1| (AF230627) proline permease [Escherichia coli] >gi|7288801|gb|AAF45289.1| (AF230628) proline permease [Escherichia coli] >gi|7288803|gb|AAF45290.1| (AF230629) proline permease [Escherichia coli] >gi|7288805|gb|AAF45291.1| (AF230630) proline permease [Escherichia coli] >gi|7288807|gb|AAF45292.1| (AF230631) proline permease [Escherichia coli] >gi|7288809|gb|AAF45293.1| (AF230632) proline permease [Escherichia coli] >gi|7288811|gb|AAF45294.1| (AF230633) proline permease [Escherichia coli] >gi|7288813|gb|AAF45295.1| (AF230634) proline permease [Escherichia coli] >gi|7288815|gb|AAF45296.1| (AF230635) proline permease [Escherichia coli] Length = 232 Score = 132 bits (329), Expect = 8e-30 Identities = 78/237 (32%), Positives = 124/237 (51%), Gaps = 11/237 (4%) Query: 34 DFSIAGRQLPGWVAALSERATGESAWCLLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVF 93 D+ + GR L +V ALS A+ S W L+GLPG F +G++ W AIG LG + W + Sbjct: 3 DYILGGRSLGPFVTALSAGASDMSGWLLMGLPGAVFLSGISESWIAIGLTLGAWINWKLV 62 Query: 94 AGRLRKEAE-KYDAVTFVDYIAKRHPEAEKWIRILGSATIAFFFFFYVGAQYLGGGKVLN 152 AGRLR E +A+T DY R + + +RI+ + I FF Y + + G ++ Sbjct: 63 AGRLRVHTEYNNNALTLPDYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARLFE 122 Query: 153 TLFGLDPKLGMLITALVILPYTVMGGLKSVAYTDTVQAIVMILTLIVAPIVGVIYIANHP 212 + FG+ + + A + YT +GG +V++TDTVQA +MI LI+ P++ +I + Sbjct: 123 STFGMSYETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGG-- 180 Query: 213 ELYATSVTAALSKAGVKYSTILGGMAGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMA 269 + S+ K+ ++ +L G+ V +I+ W GY G P + RFMA Sbjct: 181 --FGDSLEVIKQKS-IENVDMLKGL----NFVAIISLMGWGLGYF-GQPHILARFMA 229 >gb|AAF45264.1| (AF230603) proline permease [Escherichia coli] >gi|7288755|gb|AAF45266.1| (AF230605) proline permease [Escherichia coli] >gi|7288759|gb|AAF45268.1| (AF230607) proline permease [Escherichia coli] >gi|7288761|gb|AAF45269.1| (AF230608) proline permease [Escherichia coli] >gi|7288763|gb|AAF45270.1| (AF230609) proline permease [Escherichia coli] >gi|7288767|gb|AAF45272.1| (AF230611) proline permease [Escherichia coli] Length = 232 Score = 132 bits (329), Expect = 8e-30 Identities = 78/237 (32%), Positives = 124/237 (51%), Gaps = 11/237 (4%) Query: 34 DFSIAGRQLPGWVAALSERATGESAWCLLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVF 93 D+ + GR L +V ALS A+ S W L+GLPG F +G++ W AIG LG + W + Sbjct: 3 DYILGGRSLGPFVTALSAGASDMSGWLLMGLPGAVFLSGISESWIAIGLTLGAWINWKLV 62 Query: 94 AGRLRKEAE-KYDAVTFVDYIAKRHPEAEKWIRILGSATIAFFFFFYVGAQYLGGGKVLN 152 AGRLR E +A+T DY R + + +RI+ + I FF Y + + G ++ Sbjct: 63 AGRLRVHTEYNNNALTLPDYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARLFE 122 Query: 153 TLFGLDPKLGMLITALVILPYTVMGGLKSVAYTDTVQAIVMILTLIVAPIVGVIYIANHP 212 + FG+ + + A + YT +GG +V++TDTVQA +MI LI+ P++ +I + Sbjct: 123 STFGMSYETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGG-- 180 Query: 213 ELYATSVTAALSKAGVKYSTILGGMAGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMA 269 + S+ K+ ++ +L G+ V +I+ W GY G P + RFMA Sbjct: 181 --FGDSLEVIKQKS-IENVDMLKGL----NFVAIISLMGWGLGYF-GQPHILARFMA 229 >gb|AAF45285.1| (AF230624) proline permease [Escherichia coli] Length = 232 Score = 132 bits (329), Expect = 8e-30 Identities = 78/237 (32%), Positives = 124/237 (51%), Gaps = 11/237 (4%) Query: 34 DFSIAGRQLPGWVAALSERATGESAWCLLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVF 93 D+ + GR L +V ALS A+ S W L+GLPG F +G++ W AIG LG + W + Sbjct: 3 DYILGGRSLGPFVTALSAGASDMSGWLLMGLPGAVFLSGISESWIAIGLTLGAWINWKLV 62 Query: 94 AGRLRKEAE-KYDAVTFVDYIAKRHPEAEKWIRILGSATIAFFFFFYVGAQYLGGGKVLN 152 AGRLR E +A+T DY R + + +RI+ + I FF Y + + G ++ Sbjct: 63 AGRLRVHTEYNNNALTLPDYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARLFE 122 Query: 153 TLFGLDPKLGMLITALVILPYTVMGGLKSVAYTDTVQAIVMILTLIVAPIVGVIYIANHP 212 + FG+ + + A + YT +GG +V++TDTVQA +MI LI+ P++ +I + Sbjct: 123 STFGMSYETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGG-- 180 Query: 213 ELYATSVTAALSKAGVKYSTILGGMAGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMA 269 + S+ K+ ++ +L G+ V +I+ W GY G P + RFMA Sbjct: 181 --FGDSLEVIKQKS-IENVDMLKGL----NFVAIISLMGWGMGYF-GQPHILARFMA 229 >gb|AAF45286.1| (AF230625) proline permease [Escherichia coli] Length = 232 Score = 130 bits (323), Expect = 4e-29 Identities = 77/237 (32%), Positives = 124/237 (51%), Gaps = 11/237 (4%) Query: 34 DFSIAGRQLPGWVAALSERATGESAWCLLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVF 93 D+ + GR L +V ALS A+ S W L+GLPG F +G++ W AIG LG + W + Sbjct: 3 DYILGGRSLGPFVTALSVGASDMSGWLLMGLPGAVFLSGISESWIAIGLTLGAWINWKLV 62 Query: 94 AGRLRKEAE-KYDAVTFVDYIAKRHPEAEKWIRILGSATIAFFFFFYVGAQYLGGGKVLN 152 AGRLR E +A+T +Y R + + +RI+ + I FF Y + + G ++ Sbjct: 63 AGRLRVHTEYNNNALTLPNYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARLFE 122 Query: 153 TLFGLDPKLGMLITALVILPYTVMGGLKSVAYTDTVQAIVMILTLIVAPIVGVIYIANHP 212 + FG+ + + A + YT +GG +V++TDTVQA +MI LI+ P++ +I + Sbjct: 123 STFGMSYETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGG-- 180 Query: 213 ELYATSVTAALSKAGVKYSTILGGMAGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMA 269 + S+ K+ ++ +L G+ V +I+ W GY G P + RFMA Sbjct: 181 --FGDSLEVIKQKS-IENVDMLKGL----NFVAIISLMGWGLGYF-GQPHILARFMA 229 >pir||E70201 pantothenate permease (panF) homolog - Lyme disease spirochete >gi|2688763|gb|AAC67168.1| (AE001180) pantothenate permease (panF) [Borrelia burgdorferi] Length = 444 Score = 127 bits (317), Expect = 2e-28 Identities = 106/425 (24%), Positives = 208/425 (48%), Gaps = 22/425 (5%) Query: 35 FSIAGRQLPGWVAALSERATGESAWCLLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFA 94 + +A R + V AL ++ SA + P + GL+ I A + ++ + + Sbjct: 6 YFLANRNINFIVMALLFSSSYISASSFISGPSAVYKYGLSFILLATIQIPTTLIVFIIVG 65 Query: 95 GRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTL 154 RL +E++K +A+ +DYI RH ++ ++ + FF F + AQ +GG K++ Sbjct: 66 QRLNRESKKINAINIIDYI--RHRYESDFLALMSGFVLIFFSMFLISAQLIGGAKLIEVF 123 Query: 155 FGLDPKLGMLITALVILPYTVMGGLKSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPEL 214 +G+D +G+ A ++ Y GG K+VAYTD +Q +M+++ ++ + L Sbjct: 124 WGIDYVVGLTFFAFLVFIYVFFGGFKAVAYTDLIQGFLMLVSSVILFSKMLDLGGGINNL 183 Query: 215 YATSVTAALSKAGVKYSTILGGMAGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDK 274 + T+ T++L K S +L A + G L G PQ+ F+A KD+ Sbjct: 184 FKTA-TSSLDK-----SLLLPSNADLKPQYIISFWILIGIGIL-GQPQIINNFIAFKDEN 236 Query: 275 NAKLARNIGIGWTIIAYIGALM--IGWIGIAIFGPNGLKDPEQVMPSVMLKLFPPALAAV 332 K ++ I II+++ LM IG+ I +F L ++V+ +V LK+ P + Sbjct: 237 AIKF--SLPISTFIISFLIVLMHLIGFFAIILF--PDLSPNDKVVLNVALKVLNPFSCFM 292 Query: 333 FITGAVAAMLSTADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVS--LGIIA 390 F G ++A++ST DS L+L ++ ++I +IYK D ++ + + R+ +S I+ Sbjct: 293 FFIGLLSAIMSTVDSNLLLITSVLIKSI---FIYKE--DLKEDVKIGRIIMISNIFFILI 347 Query: 391 LIMAYVVPSHLIYTIVGYTWAGIGDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWI 450 +++ + P + ++ I + + + +F I++ L+ A ++ GL+F + + Sbjct: 348 ILIFSLFPPNFLFFINIFAFGALEVSFFPIIVFGLYLNFVSKIAAFASMFLGLIFYLSIL 407 Query: 451 SSGLD 455 GL+ Sbjct: 408 FFGLN 412 >sp|P39599|YWCA_BACSU HYPOTHETICAL 55.0 KD PROTEIN IN EPR-GALK INTERGENIC REGION >gi|7442759|pir||S39686 Na+-dependent symport homolog ywcA - Bacillus subtilis >gi|580869|emb|CAA51587.1| (X73124) ipa-31r [Bacillus subtilis] >gi|2636359|emb|CAB15850.1| (Z99123) alternate gene name: ipa-31r~similar to Na+-dependent symport [Bacillus subtilis] Length = 516 Score = 120 bits (299), Expect = 3e-26 Identities = 107/441 (24%), Positives = 203/441 (45%), Gaps = 30/441 (6%) Query: 23 IYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGFAFAAGLAAIWPAIGC 82 ++ ++ K+ +F AG L G L+ SA LG+ G G + +IG Sbjct: 24 VFCAKRTKTTSEFYTAGGGLTGVQNGLAIAGDYMSAASFLGIAGMIALYGFDGFFYSIGF 83 Query: 83 VLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRILGSATIAFFFFFYVGA 142 ++ +V + A LR KY T D IA R E K IR + + FY+ A Sbjct: 84 LVAYLVVLYIVAEPLRNLG-KY---TMADMIAARFKE--KKIRGVAALNTIAISTFYMIA 137 Query: 143 QYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTDTVQAIVMIL-TLIVAP 201 Q +G G ++ L GLD +LI +++ Y V GG+ + ++ ++A++++ TL+++ Sbjct: 138 QLVGAGALIKLLLGLDYTAAVLIVGVLMTIYVVFGGMIATSWVQIIKAVLLMAGTLVISI 197 Query: 202 IVGVIYIANHPELY-----ATSVTAALSKAGVKYSTILGGMAGAAAIVFVIAEFSWFFGY 256 IV + + ++ AT + A G KY L ++ A+V A Sbjct: 198 IVFSKFGFSLNTMFEQMKTATPLGADFLNPGNKYKVPLETLSLNLALVLGTA-------- 249 Query: 257 LGGMPQLSIRFMAIKDDKNAKLARNIGIGWTI-IAYIGALMIGWIGIAIFGPNGLKDPEQ 315 G+P + IRF +KD K A+ + + W I + YI + +G+ A G + + +Q Sbjct: 250 --GLPHILIRFYTVKDAKTARTSV-VSATWIIGVFYIMTVFLGFGAAAFVGFDAITAADQ 306 Query: 316 VMPSVMLKLFPPALAAVFITGAVAAM-----LSTADSLLILSSTEFSENILKPYIYKNEA 370 ++ L AL F+ V+A+ L+ L++ +++ F+ +I I K EA Sbjct: 307 A-GNMAAPLLAKALGGDFLFAFVSAIAFATILAVVTGLVLSAASAFAHDIYSQIIRKGEA 365 Query: 371 DPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVIVILTLFWKRF 430 ++ + +R +V++ ++++++A S + +V +A +++ T+FWKRF Sbjct: 366 TEKEQMKAARWASVAVSVLSILLAIFAQSLNVAFLVALAFAVAASANLPLIVFTVFWKRF 425 Query: 431 HGKAVPPTIIAGLLFTVFWIS 451 + + GL+ + +S Sbjct: 426 NASGALWGSLTGLISALVLVS 446 >pir||JU0296 pantothenate permease - Escherichia coli >gi|147067|gb|AAA24276.1| (M30953) pantothenate permease (panF) [Escherichia coli] Length = 482 Score = 118 bits (292), Expect = 2e-25 Identities = 115/458 (25%), Positives = 217/458 (47%), Gaps = 40/458 (8%) Query: 6 QILAVLVFYLGFLISVGIYQGRKAKSH---KDFSIAGRQLPGWVAALSERATGESAWCLL 62 +++ LV YL + + +Y RK + ++ + R + G V A++ AT SA + Sbjct: 4 EVILPLVAYLVVVFGISVYAMRKRSTGTFLNEYFLGSRSMGGIVLAMTLTATYISASSFI 63 Query: 63 GLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEK 122 G PG A+ GL + A+ + + ++ + + A +Y+AVT D + R+ + Sbjct: 64 GGPGAAYKYGLGWVLLAMIQLPAVWLSLGILGKKFAILARRYNAVTLNDMLFARYQS--R 121 Query: 123 WIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSV 182 + L S ++ F + Q++GG ++L T G+ + G+LI + I YT GG Sbjct: 122 LLVWLASLSLLVAFVGAMTVQFIGGARLLETAAGIPYETGLLIFGISIALYTAFGGFAPA 181 Query: 183 AYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTI---LGGMAG 239 A +A A + ++ LS A TI L G Sbjct: 182 AERHHARACDADWHRCAA-------------YWRSTCAGGLSNAVQTLQTIDPQLVTPQG 228 Query: 240 AAAIVFVIAEFSWF----FGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYI--G 293 A I+ S++ FG +G + ++R ++ KD K + R I IG ++A + G Sbjct: 229 ADDILSPAFMTSFWVLVCFGVIG-LAHTAVRCISYKDSK--AVHRGIIIGTIVVAILMFG 285 Query: 294 ALMIGWIGIAIFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353 + G +G A+ L P+ V+P++M+K+ PP A +F+ +AA++ST ++ L+ SS Sbjct: 286 MHLAGALGRAVIPD--LHVPDLVIPTLMVKVLPPFAAGIFLAAPMAAIMSTINAQLLQSS 343 Query: 354 TEFSENI---LKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTW 410 +++ ++P +NE ++ +S + T+ LG + L+ A+ P +I+ + + Sbjct: 344 ATIIKDLYLNIRPDQMQNETRLKR---MSAVITLVLGALLLLAAWKPPEMIIWLNL-LAF 399 Query: 411 AGIGDTFSVIVILTLFWKRFHGK-AVPPTIIAGLLFTV 447 G+ F ++L L+W+R + K A+ I+ G+L+ V Sbjct: 400 GGLEAVFLWPLVLGLYWERANAKGALSAMIVGGVLYAV 437 >pir||F83241 probable sodium:solute symporter PA3234 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9949356|gb|AAG06622.1|AE004746_6 (AE004746) probable sodium:solute symporter [Pseudomonas aeruginosa] Length = 551 Score = 117 bits (291), Expect = 2e-25 Identities = 102/437 (23%), Positives = 201/437 (45%), Gaps = 31/437 (7%) Query: 8 LAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGF 67 + + V ++G + + + ++ +S D+ AG ++ G+ L+ SA LG+ Sbjct: 37 IVMFVAFVGATLCITYWASKRNRSAADYYAAGGRITGFQNGLAIAGDYMSAASFLGISAL 96 Query: 68 AFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRIL 127 F +G + +IG ++G + + A RLR KY TF D + R + K IR L Sbjct: 97 VFTSGYDGLIYSIGFLVGWPIILFLIAERLRNLG-KY---TFADVASYRLKQ--KQIRTL 150 Query: 128 GSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTDT 187 + FY+ AQ +G GK++ LFGL+ + +++ ++++ Y + GG+ + + Sbjct: 151 SACGSLVVVAFYLIAQMVGAGKLIELLFGLNYHVAVVLVGILMVLYVLFGGMLATTWVQI 210 Query: 188 VQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTIL--GGMAGAAAIVF 245 ++A++ L+ I + H +++ + K K I+ GG+ F Sbjct: 211 IKAVL----LLSGASFMAIMVLKHVNFDVSTLFSEAIKVHPKGEAIMSPGGLVKDPISAF 266 Query: 246 VIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGWIGIAIF 305 + F+ FG G+P + +RF + D K A+ + G+ YI +IG+ I + Sbjct: 267 SLG-FALMFG-TAGLPHILMRFFTVSDAKEARKSVFYATGFIGYFYILTFIIGFGAILLV 324 Query: 306 GPN-GLKDPEQV------MPSVML------KLFPPALAAVFITGAVAAMLSTADSLLILS 352 N KD M +V L LF ++AV A A +L+ L + Sbjct: 325 STNPDFKDATGALIGGNNMAAVHLADAVGGSLFLGFISAV----AFATILAVVAGLTLAG 380 Query: 353 STEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAG 412 ++ S ++ +A+ + L VS++TTV+LG++A+++ + I +VG ++ Sbjct: 381 ASAVSHDLYASVFKGGKANEKDELRVSKMTTVALGVVAIVLGILFEKQNIAFMVGLAFSI 440 Query: 413 IGDTFSVIVILTLFWKR 429 +++L+++WK+ Sbjct: 441 AASCNFPVLLLSMYWKK 457 >emb|CAB59438.1| (AL132644) putative transmembrane transport protein [Streptomyces coelicolor A3(2)] Length = 544 Score = 117 bits (290), Expect = 3e-25 Identities = 108/466 (23%), Positives = 205/466 (43%), Gaps = 32/466 (6%) Query: 2 EARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCL 61 E R I+ + ++ + + ++ GR+ K DF GRQ + L+ SA Sbjct: 19 EHRPLIITLFAVFVLATLGITVWAGRQTKDAADFYAGGRQFSAFQNGLAVSGDYMSAASF 78 Query: 62 LGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAE 121 LG+ G G +IG ++ +VA + A LR +Y + Y ++ P Sbjct: 79 LGIAGAIALFGYDGFLYSIGFLVAWLVALLLVAEPLRNSG-RYTMGDVLAYRMRQRP--- 134 Query: 122 KWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLG-MLITALV---ILPYTVMG 177 +R + FY+ AQ G G +++ L G+ G +LI ALV ++ Y +G Sbjct: 135 --VRTAAGTSTIVVSIFYLLAQMAGAGILVSLLLGITSDAGKILIVALVGVLMIVYVTIG 192 Query: 178 GLKSVAYTDTVQAIVMIL-TLIVAPIVGVIYIANHPELYATSVT-----AALSKAGVKYS 231 G+K + V+A+++I T+++ +V + + N +L + +A + G++Y Sbjct: 193 GMKGTTWVQMVKAVLLIGGTILITFLVLLKFDFNISDLLGKAAENSGAGSAFLEPGLQY- 251 Query: 232 TILGGMAGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAY 291 G +G + F+ + G G+P + IRF + + K A+ + N IG Y Sbjct: 252 ----GASGTTKLDFISLGIALVLG-TAGLPHILIRFYTVPNAKAARKSVNWAIGIIGAFY 306 Query: 292 IGALMIGWIGIAIFGPNGL--KDPEQVMPSVMLKL--------FPPALAAVFITGAVAAM 341 + + +G+ A+ G + + +P + +L L + L A A A + Sbjct: 307 LMTIALGFGAAALVGKDEIIASNPSGNTAAPLLALHVGGVDSTWGAILLATISAVAFATI 366 Query: 342 LSTADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHL 401 L+ L + SS+ F+ +I I K +A ++ + +R TV +GI+++ + + Sbjct: 367 LAVVAGLTLASSSSFAHDIYANVIRKGQATEKEEMRAARWATVFIGIVSIALGALARDLN 426 Query: 402 IYTIVGYTWAGIGDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTV 447 + +V +A ++ +LFWKRF + +I GL+ V Sbjct: 427 VAGLVALAFAVAASANLPTILYSLFWKRFTTQGALWSIYGGLIVAV 472 >sp|P32705|YJCG_ECOLI HYPOTHETICAL 59.2 KD PROTEIN IN SOXR-ACS INTERGENIC REGION (F549) >gi|7442761|pir||B65215 hypothetical 59.2 kD protein in soxR-acs intergenic region - Escherichia coli (strain K-12) >gi|396402|gb|AAC43161.1| (U00006) similar to Salmonella proline permease [Escherichia coli] >gi|1790503|gb|AAC77037.1| (AE000480) putative transport protein [Escherichia coli K12] Length = 549 Score = 111 bits (274), Expect = 2e-23 Identities = 103/450 (22%), Positives = 200/450 (43%), Gaps = 54/450 (12%) Query: 6 QILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLP 65 Q + + + ++ F + + + ++ +S D+ AG + G+ L+ SA LG+ Sbjct: 34 QAIIMFLIFVVFTLGITYWASKRVRSRSDYYTAGGNITGFQNGLAIAGDYMSAASFLGIS 93 Query: 66 GFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIR 125 F +G + ++G ++G + + A RLR +Y Y K+ P IR Sbjct: 94 ALVFTSGYDGLIYSLGFLVGWPIILFLIAERLRNLG-RYTFADVASYRLKQGP-----IR 147 Query: 126 ILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYT 185 IL + Y+ AQ +G GK++ LFGL+ + +++ ++++ Y + GG+ + + Sbjct: 148 ILSACGSLVVVALYLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWV 207 Query: 186 DTVQAIVMI-----LTLIVAPIVGVIY-------IANHPELYATSVTAALSKAGVKYSTI 233 ++A++++ + +V VG + +A HP+ L K + ++ Sbjct: 208 QIIKAVLLLFGASFMAFMVMKHVGFSFNNLFSEAMAVHPKGVDIMKPGGLVKDPISALSL 267 Query: 234 -LGGMAGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYI 292 LG M G A G+P + +RF + D + A+ + G+ YI Sbjct: 268 GLGLMFGTA-----------------GLPHILMRFFTVSDAREARKSVFYATGFMGYFYI 310 Query: 293 GALMIGWIGIAIFGPN-GLKDPE------QVMPSVML------KLFPPALAAVFITGAVA 339 +IG+ I + G N KD M +V L LF ++AV A A Sbjct: 311 LTFIIGFGAIMLVGANPEYKDAAGHLIGGNNMAAVHLANAVGGNLFLGFISAV----AFA 366 Query: 340 AMLSTADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPS 399 +L+ L + ++ S + L ++K A R+ L VS++T + LG+IA+I+ + + Sbjct: 367 TILAVVAGLTLAGASAVSHD-LYANVFKKGATEREELRVSKITVLILGVIAIILGVLFEN 425 Query: 400 HLIYTIVGYTWAGIGDTFSVIVILTLFWKR 429 I +VG +A I++L+++W + Sbjct: 426 QNIAFMVGLAFAIAASCNFPIILLSMYWSK 455 >dbj|BAB07462.1| (AP001519) Na+/solute symporter (Ssf family) [Bacillus halodurans] Length = 554 Score = 109 bits (271), Expect = 5e-23 Identities = 109/486 (22%), Positives = 206/486 (41%), Gaps = 51/486 (10%) Query: 7 ILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPG 66 I+++L+ F + +GI +A++ DF +A R +P + ++ SA +G+ G Sbjct: 6 IVSILMILATFGLYIGISIYNRARATSDFYVASRGVPPFWNGMAIGGDWMSAASFIGMAG 65 Query: 67 FAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRI 126 G + +G G + +FA +LRK Y T ++I R+ R+ Sbjct: 66 TIMILGYDGLAYIMGWTGGYLFLTFLFAPQLRK----YGRYTVPEFIGDRY--GSNTARL 119 Query: 127 LGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTD 186 + + F Y+ Q G G V+ + + G +I +VI Y +GG+K + +T Sbjct: 120 IAAIATIIISFTYIIGQLSGSGVVIGRILNIPAMYGTMIGVVVIAIYATLGGMKGITWTQ 179 Query: 187 TVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVK----YSTILGGMAGAAA 242 Q I++I+ I+ + + ++ +P + T G+ S IL + Sbjct: 180 VAQYIILIVAYIIPIVFMSLQLSGNPFPWLTYGNFISQLDGLDQELGLSQILQPFMESDK 239 Query: 243 IVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGA-------- 294 F+ F+ G +P + +RF + K A+ + + + + Y+ A Sbjct: 240 SQFIALMFTLMVG-TAALPHVIVRFYTVTTMKAARWSGAWALIFIALLYLSAPAYAAFSR 298 Query: 295 --LMI---------------GWIGIAIF------GPNGLKDPEQVMPSVMLKLFPPALA- 330 LM WI + G L+ E + + ++ + P +A Sbjct: 299 FILMTQVANQPIDQLPAWTEAWINTGLLEMADANGDGILQWEELRISNDIVVMATPEIAN 358 Query: 331 ------AVFITGAVAAMLSTADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTV 384 + GA+AA LSTA LLI S+ F+ +I + +A +K L+ R+ V Sbjct: 359 LGMFVIGLVAAGAMAAALSTAGGLLITISSSFAHDIYY-RLMNPKASDQKRLLAGRIAIV 417 Query: 385 SLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVIVILTLFWKRFHGKAVPPTIIAGLL 444 I+A ++A + P +I IV + + G F +++L ++WKR + K +++GL Sbjct: 418 LATIVAGVVA-LDPPGVITQIVAWAFGLAGGAFFPVLLLGVWWKRANAKGAIAGMLSGLA 476 Query: 445 FTVFWI 450 T+ +I Sbjct: 477 VTLVYI 482 >gi|11498574 proline permease (putP-2) [Archaeoglobus fulgidus] >gi|7442764|pir||A69371 proline permease (putP-2) homolog - Archaeoglobus fulgidus >gi|2649629|gb|AAB90273.1| (AE001037) proline permease (putP-2) [Archaeoglobus fulgidus] Length = 531 Score = 105 bits (260), Expect = 1e-21 Identities = 116/491 (23%), Positives = 215/491 (43%), Gaps = 63/491 (12%) Query: 2 EARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCL 61 + ++ + V Y +I +G Y ++ KS D+ +AGRQ+ V L+ +T S + Sbjct: 3 QVEAPVIGITVLYFLAIIIIGYYSRQRLKSATDYYVAGRQVGAVVNGLALESTYLSPASM 62 Query: 62 LGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAE 121 LGLP + F G W + G+ +A + A LR KY +F DY A R+ + Sbjct: 63 LGLPAYIFILGYPFWWAMSAIIAGMPIATLLTASALR----KYAPTSFADYYADRYNDQR 118 Query: 122 -KWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLK 180 +W ++G T+ Y+ +G L + + +G+++ ++++ Y V GG+ Sbjct: 119 LRW--LVGIVTV-IGAVLYITLSLVGMALFLLAVAKVPYIIGLIVGTIIVMLYVVWGGMI 175 Query: 181 SVAYTDTVQAIVMILTLIVAPIVGVI-----------YIANHPELYATSVTAALSKAGVK 229 + ++ QA +M + ++A V VI +AN+P+ + T + + Sbjct: 176 ATSWNAAFQAFLMTVAAVIAAAVIVIKLGGLGGFYEAVLANNPKFWNT-------PSDPE 228 Query: 230 YSTILGGMAGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNI------- 282 +L G A F F W +G+ MP +RF D K A+ R+I Sbjct: 229 PPHLLSGTWIAVIGWF----FVWHYGF-ATMPYTVVRFFTTMDIKTAR--RSIFWCTLAA 281 Query: 283 GIGWTIIAYIGA---LMI--GWIG-------------IAIFGPNGLKDPEQVMPSVMLKL 324 GI + + IGA LMI G +G +A +G G D + + + L Sbjct: 282 GIFYMALEIIGAASKLMIETGPMGGEGANAVKILQSYMAQYGVGGWTDYSMI--AAVEAL 339 Query: 325 FPPALAAVFITGAVAAMLSTADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTV 384 P + + G +A +STA +++ +T + + + K++ K + ++R+ +V Sbjct: 340 QNPWVLGILCAGGLAIAMSTAAGWVMVVNTLLTRD-WGDMLLKSKFAKEKPVTLARIISV 398 Query: 385 SLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVIVILTLFWKRFHGKAVPPT-IIAGL 443 I+ ++A + P L+ + G+ + I ++L L+WKR A+ T I+ Sbjct: 399 IFLIVGFLVA-INPPGLVLDLSGWAFVVIISALGPGLVLGLWWKRATRAAMWTTAIVMTP 457 Query: 444 LFTVFWISSGL 454 L W+ + L Sbjct: 458 LHLYAWLKAKL 468 >pir||C82582 Na+-dependent symport homolog XF2251 [imported] - Xylella fastidiosa (strain 9a5c) >gi|9107405|gb|AAF85050.1|AE004037_11 (AE004037) solute:Na+ symporter [Xylella fastidiosa] Length = 577 Score = 104 bits (257), Expect = 2e-21 Identities = 101/447 (22%), Positives = 200/447 (44%), Gaps = 32/447 (7%) Query: 7 ILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPG 66 ++++ V ++ + + + ++ +S DF AG + G+ L+ SA LG+ Sbjct: 38 VISIFVVFVLITLWITKWAAKRTRSSADFYTAGGTITGFQNGLAMAGDYMSAAAFLGITS 97 Query: 67 FAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRI 126 +G + AIG ++G + + A RLR KY TF D +A R +R+ Sbjct: 98 AVMISGYDGMLYAIGSLVGWPILVFLVAERLRNLG-KY---TFADVVAYRFAAVP--VRL 151 Query: 127 LGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTD 186 SA+ + AQ +G G ++ LFGLD + +++ +++ Y + GG+ + + Sbjct: 152 FTSASTLVVVLCSLVAQMVGAGALIKLLFGLDYWVAVILVGGLMMVYVMFGGMAATTWVQ 211 Query: 187 TVQAIVMILTL-IVAPIVGVIYIANHPELYA------TSVTAALSKAGVKYSTI-LGGMA 238 ++A++++ L +A ++ + N L+A T + A K+G + + L MA Sbjct: 212 IIKAVLLLTCLTFMAVMIMWRFGFNFEGLFASAVGVKTQIAMAGGKSGEEAKALGLSIMA 271 Query: 239 GAAAIVFVIAEFSW----FFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGA 294 + I I+ S FG +G +P + +RF A+ D + + + I W YI Sbjct: 272 PGSFIKDPISAISLGIALVFGNVG-LPHILMRFFAVPDAREVRHSVLWAITWIGYCYILM 330 Query: 295 LMIGWIGIAIFGPN------------GLKDPEQVMPSVMLKLFPPALAAVFITG-AVAAM 341 ++G+ I N G + + ++ K+ + F++ A A + Sbjct: 331 FIVGFGAIVFVLTNPQYADIATGTIRGGQGAANMAAVLVAKVVGGDVFMGFVSAVAFATI 390 Query: 342 LSTADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHL 401 L+ A L + ++ S ++ I + + L+VSR+TT LG++A+++ V Sbjct: 391 LAVAAGLALSGASAVSHDVYAMVIKQGKPSSDTELLVSRVTTAVLGVVAVLLGIVFQKQN 450 Query: 402 IYTIVGYTWAGIGDTFSVIVILTLFWK 428 + +V +A ++IL+L WK Sbjct: 451 VAFMVSLAFAIAASANFPVLILSLLWK 477 >pir||H75513 probable sodium/proline symporter DR0477 [similarity] - Deinococcus radiodurans (strain R1) >gi|6458165|gb|AAF10057.1|AE001907_3 (AE001907) sodium:solute symporter protein [Deinococcus radiodurans] Length = 528 Score = 102 bits (252), Expect = 9e-21 Identities = 96/464 (20%), Positives = 203/464 (43%), Gaps = 35/464 (7%) Query: 5 TQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGL 64 T +LA L+ + + V + + S DF +AG ++ ++ SA LG+ Sbjct: 2 TFLLAALIVLI--TLGVTFWASSRNTSAGDFYVAGGKISATQNGIAIAGDYMSAASFLGI 59 Query: 65 PGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWI 124 G G ++G + + + A LR KY + Y K ++ + Sbjct: 60 TGLIALNGYDGFMYSVGWFIAYLTVLFIVAEPLRNLG-KYTLADMLVYRLK-----DQRV 113 Query: 125 RILGSATIAFFFFFYVGAQYLGGGKVLNTLFG--LDPKLGMLITALVILPYTVMGGLKSV 182 R + + FY+ AQ +G G +++ L G L P L + + L+++ Y V+GG+ + Sbjct: 114 RFYAAFSTITVSTFYMIAQVVGAGSLISLLSGGLLKPTLAIPLVGLLMIVYVVVGGMLAT 173 Query: 183 AYTDTVQA-IVMILTLIVAPIVGVIYIANHPELYATSVT---AALSKAGVKYSTILGGMA 238 + ++A ++M T++++ ++ + + +L + AA + G+KY L ++ Sbjct: 174 TWVQIIKAMLLMFATIVMSVLILARFGFSFSDLLGAATDKNGAAFLEPGLKYKNPLDLIS 233 Query: 239 GAAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIG 298 A+V A G+P + +RF + ++A+ + + +G YI ++G Sbjct: 234 LCLALVLGTA----------GLPHILVRFFTVPTAQDARKSVVVAMGLIGAFYIMTALMG 283 Query: 299 WIGIAIFGPNGL--KDPEQVMPSVMLK--------LFPPALAAVFITG-AVAAMLSTADS 347 + G + + +P M + +L F+T A A +L+ Sbjct: 284 NAANVLVGKDTIVAANPAGNMAAPLLAQALGGGAGTLGGEFGLAFVTAVAFATILAVVAG 343 Query: 348 LLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVG 407 L I +ST F+ +I + +A+ ++ V+R+ TV++G++++++ + + +V Sbjct: 344 LTISASTSFTHDIYNGVMKGGKANEQEQFKVARMATVAVGLLSIVLGLLAKDQNVAFLVA 403 Query: 408 YTWAGIGDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWIS 451 +A +++ TLFW+ F+ I+ GL T+ I+ Sbjct: 404 LAFAIAASANLPVILYTLFWRGFNANGAVWGIVGGLAVTLVLIA 447 >gi|11497853 pantothenate permease (panF-3) [Archaeoglobus fulgidus] >gi|7442769|pir||E69279 pantothenate permease (panF-3) homolog - Archaeoglobus fulgidus >gi|2650404|gb|AAB90996.1| (AE001089) pantothenate permease (panF-3) [Archaeoglobus fulgidus] Length = 461 Score = 102 bits (251), Expect = 1e-20 Identities = 96/407 (23%), Positives = 201/407 (48%), Gaps = 37/407 (9%) Query: 6 QILAVLVFYLGFLI---SVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLL 62 +++ L ++G++I ++ I + ++ +++ IAGR++ G ++AL+ AT SA+ ++ Sbjct: 3 KLIEFLYAFIGYIIIGTAIAIMAMKGLRTQEEYYIAGRKVSGVISALTYAATTYSAFMMV 62 Query: 63 GLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRH-PEAE 121 GL G ++ +G+ A+ + ++G + + +A R+ + A++ VT D IA+R+ E Sbjct: 63 GLVGLSYFSGVGALGFELFYLVGTLFLLSYYAPRVWEMAKERGYVTPGDMIAERYGSEVA 122 Query: 122 KWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKS 181 K + ++ ++ Y+ Q +G +L+ + + G++ +A++I + +GGL+ Sbjct: 123 KLMAVI----VSIALIPYISVQLIGVSLILSKTNAMSFEAGIVASAILIALWAFLGGLRG 178 Query: 182 VAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAA 241 VA+TD +Q + M+L + +A I+ V + + T V + L + V ++I Sbjct: 179 VAWTDALQGVFMLL-MAIAAILWVHQYGFAEKDFFTEV-SRLGELLVVPNSIW------T 230 Query: 242 AIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGW------TIIAYIGAL 295 + F+ WFF L PQ+ R + I D++A I G+ I+ IG Sbjct: 231 PVKFISLTLPWFFFALTN-PQVFQR-LYIPKDRSALRRMVILFGFFGLIYTVIVTLIGLE 288 Query: 296 MIGWIGIAIFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTE 355 + + +F + D + V P+ ML + PP L A AA ++TA+S+++ S+ Sbjct: 289 LRTMTEMGVFPK--VPDRDAVTPT-MLAMMPPLLGAAISLSIFAAAITTANSIVLTLSSM 345 Query: 356 FSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLI 402 + ++L + + R+ V L + + AY P +++ Sbjct: 346 ITRDLL----------GSEKVGSGRVLIVILTVAVALFAYSRPGYIV 382 >gi|11497636 proline permease (putP-1) [Archaeoglobus fulgidus] >gi|7442766|pir||G69251 proline permease (putP-1) homolog - Archaeoglobus fulgidus >gi|2650635|gb|AAB91210.1| (AE001105) proline permease (putP-1) [Archaeoglobus fulgidus] Length = 491 Score = 101 bits (250), Expect = 2e-20 Identities = 103/481 (21%), Positives = 196/481 (40%), Gaps = 27/481 (5%) Query: 3 ARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLL 62 A T +++++ Y +++G + RK K+ + + A + +V A++ + SA+ + Sbjct: 2 ADTITVSIVLAYFVVTLALGFFAARKIKTAEHYYGARKLFGMFVTAVAVFSGIASAFTFI 61 Query: 63 GLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEK 122 G PG + G W V+ + + W + R++ E T D A R Sbjct: 62 GGPGLVYPMGGTVNWVIWTPVISMPLIWYLLGKRIKLITEARPVATLPDLTAARFKSDA- 120 Query: 123 WIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSV 182 +R L + + F Y+ +G G VL + G +L + I +I+ YT GG+ + Sbjct: 121 -VRFLTAVALIFGIITYLAGNVMGAGLVLTDMLGTPLELSIAIVFGIIMLYTAFGGMVAS 179 Query: 183 AYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAA 242 TD Q +VM++ I+ + +I L+AT ++++ ++ + G Sbjct: 180 ILTDFFQGLVMMVAAIIFVVFILIMTGGVENLFAT-----IAESNPRHIDPI----GVGP 230 Query: 243 IVFVIAEFSWFFGYLGGM-PQLSIRFMAIKDDKNAKLARNI-GIGWTIIA---YIGALMI 297 I I + W + P +F A+KD ++ K + I WT+ + G Sbjct: 231 IWLGIMGWWWALNIGSSVQPHAVTKFFALKDYRDLKWGALVTTIAWTLACLMWFFGGYAS 290 Query: 298 GWIGIAIFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFS 357 W+ I + + + ++ P L AV G +AA++ST + + + Sbjct: 291 VWVVIKGLAEAPARSDQAIFG--VIAQMPVVLKAVIYAGVLAAIMSTVSGFISMGTAAVV 348 Query: 358 ENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTF 417 +I P R ++ R+ TV L ++A + Y +++ +V Sbjct: 349 RDI--PTAIGKSLSQRGQILWGRVVTVILTVVAALFGY-YGGYVVGILVTLGLGYFASML 405 Query: 418 SVIVILTLFWKRFHGKA----VPPTIIAGLLFTVFWISSGLDAKVSVRLMNFIVTFIVAI 473 ++++ L WKR +A T+ L F V+ L + L + VTF V I Sbjct: 406 FPLLVIGLNWKRATKEAAIITTALTVAMNLGFLVY--EKVLSMSLPYGLPGYGVTFAVGI 463 Query: 474 I 474 I Sbjct: 464 I 464 >pir||G83610 probable sodium:solute symporter PA0287 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9946130|gb|AAG03676.1|AE004466_10 (AE004466) probable sodium:solute symporter [Pseudomonas aeruginosa] Length = 461 Score = 101 bits (249), Expect = 2e-20 Identities = 107/478 (22%), Positives = 208/478 (43%), Gaps = 45/478 (9%) Query: 10 VLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQL-PG-WVAALSERATGESAWCLLGLPGF 67 +++ Y ++ +G Y RKAKS DF +AGR+L PG ++ ++ G ++ +G Sbjct: 7 IMLVYALAMLGLGWYGMRKAKSQSDFLVAGRRLGPGLYLGTMAAVVLGGAS--TIGTVKL 64 Query: 68 AFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRIL 127 + GL+ +W LGIIV VF+ ++ + T + +R+ + R++ Sbjct: 65 GYQFGLSGLWLVFMLGLGIIVLSLVFS----RQIARLRVFTVTQVLEQRYQASS---RLI 117 Query: 128 GSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTDT 187 G + + + G V +FG+ +L +++ Y+V+GG+ S+ TD Sbjct: 118 GGVVMVAYDLMVAVTATIAIGSVTEVVFGIPRIPAILCGGGIVIVYSVIGGMWSLTLTDI 177 Query: 188 VQAIV----MILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAAI 243 +Q ++ + L L+ I G +A E+ + TIL Sbjct: 178 IQFVIKTVGIFLVLLPLSIDGAGGLARMQEVLPAGF---FDLGHIGLDTIL--------T 226 Query: 244 VFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGWIGIA 303 F++ +FFG L G F A ++ + R G+G + + IG A Sbjct: 227 YFLL----YFFGALIGQDIWQRVFTA----RSETVVRYAGLGAGVYCMLYGAACALIGAA 278 Query: 304 --IFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSENIL 361 + P+ L PE + ++ P L + + A++A++STA L+ ++T E+I Sbjct: 279 ARVLLPD-LAVPENAYAEITREVLAPGLRGLVVAAALSAIMSTASGCLLAAATVLQEDIY 337 Query: 362 KPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVIV 421 ++ + +SR T+ +G+ L++A +V + + Y G V + Sbjct: 338 ARFL---RPGTTSDIRLSRCITLLMGVAMLVLACLVNDVIAALSIAYNLLVGG--LLVPI 392 Query: 422 ILTLFWKRFHGKAVPPTIIAGLLFTVFWIS-SGL--DAKVSVRLMNFIVTFIVAIIAT 476 + L W+R + +I+AG L + ++ GL ++ + L+ + TF+ +AT Sbjct: 393 VGALLWRRASPQGAIASIVAGCLAVIACMARDGLLANSPIVYGLLASLATFVAVSLAT 450 >emb|CAA94864.1| (Z71176) phenylacetic acid permease [Pseudomonas putida] >gi|3253206|gb|AAC24338.1| (AF029714) PhaJ [Pseudomonas putida] Length = 520 Score = 101 bits (248), Expect = 3e-20 Identities = 102/468 (21%), Positives = 206/468 (43%), Gaps = 31/468 (6%) Query: 8 LAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGF 67 +++ + ++ F + V + + +S DF AG L G L+ SA LG+ Sbjct: 6 ISMFMVFVCFTLLVTRWAALRTRSASDFYTAGGGLTGMQNGLAIAGDMISAASFLGISAM 65 Query: 68 AFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRIL 127 F G + A+G + G + + A RLR KY TF D ++ R A+ +R+ Sbjct: 66 MFMNGYDGLLYALGVLAGWPIILFLIAERLRNLG-KY---TFADVVSYRL--AQTPVRLT 119 Query: 128 GSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTDT 187 + Y+ AQ +G GK++ LFG+ +++ ++++ Y GG+ + + Sbjct: 120 SAFGTLVVALMYLVAQMVGAGKLIELLFGISYLYAVMLVGVLMVAYVTFGGMLATTWVQI 179 Query: 188 VQAIVMIL-TLIVAPIVGVIYIANHPELYATSVTA-ALSKAGVKYSTILGGMAGAAAIVF 245 ++A++++ T +A +V + + ++A++V A +A + +L A ++ Sbjct: 180 IKAVMLLSGTSFMAFMVLKHFGFSTEAMFASAVAVHAKGQAIMAPGGLLSNPVDAISL-- 237 Query: 246 VIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGWIGIAIF 305 FG G+P + +RF + D K A+ + G+ Y+ ++IG+ I + Sbjct: 238 ---GLGMMFG-TAGLPHILMRFFTVSDAKEARKSVFYATGFIGYFYLLLIVIGFGAIVMV 293 Query: 306 GPN-------------GLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILS 352 G G + +V LF ++AV A A +L+ L + Sbjct: 294 GTEPSYRDATGAIIGGGNMIAVHLAQAVGGNLFLGFISAV----AFATILAVVAGLALSG 349 Query: 353 STEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAG 412 ++ S ++ I + +A ++ + VSR+ T+ +G++A+++ + S I + G A Sbjct: 350 ASAVSHDLYACVIRQGKATEQEEMRVSRIATLLIGLLAVLLGLMFESQNIAFLSGLVLAV 409 Query: 413 IGDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSGLDAKVSV 460 +++L++FWK + +AGL V + G V+V Sbjct: 410 AASVNFPVLLLSMFWKGLTTRGAVCGSMAGLASAVLLVVLGPAVWVNV 457 >pir||E83468 probable sodium:solute symport protein PA1418 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9947366|gb|AAG04807.1|AE004571_6 (AE004571) probable sodium:solute symport protein [Pseudomonas aeruginosa] Length = 463 Score = 101 bits (248), Expect = 3e-20 Identities = 121/471 (25%), Positives = 209/471 (43%), Gaps = 42/471 (8%) Query: 10 VLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQL-PGWVAALSERATGESAWCLLGLPGFA 68 V++ Y +I++G Y R+AK+ D+ +AGR L PG+ + AT +G Sbjct: 7 VVLIYAAGMIALGWYGMRRAKTRDDYLVAGRNLGPGFYLG-TMAATVLGGASTIGTVRLG 65 Query: 69 FAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRILG 128 + G++ W LGI V ++F L K K T + +R+ A + Sbjct: 66 YVHGISGFWLCGAIGLGI-VGLSLF---LAKPLLKLKIYTVTQVLERRYNPAARH----A 117 Query: 129 SATIAFFFFFYVGA-QYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTDT 187 SA I + +GA + G V+ LFGL + +LI V++ Y+ +GG+ S+ TD Sbjct: 118 SALIMLVYALMIGATSTIAIGTVMQVLFGLPFWVSILIGGGVVVLYSTIGGMWSLTLTDI 177 Query: 188 VQAIVMILTLIVAPIVGVIYIANHPELY-ATSVTAALSKAGVKYSTILGGMAGAAAIVFV 246 VQ ++M VG++++ + A A ++K Y F+ Sbjct: 178 VQFLIM--------TVGLVFLLMPLSINDAGGWDALVAKLPASYFDFTAIGWDTIVTYFL 229 Query: 247 IAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARN-IGIGWTIIAYIGALMIGWIGIA-- 303 I +FFG G + R + + AK+A + GI + GAL IG+A Sbjct: 230 I----YFFGIFIGQ-DIWQRVFTARSETVAKVAGSAAGIYCVLYGMAGAL----IGMAAK 280 Query: 304 IFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSENILKP 363 + P+ L++ SV+ P + + I A+AA++STA + L+ +ST ++++L Sbjct: 281 VLLPD-LENVNNAFASVVEHSLPNGIRGLVIAAALAALMSTASAGLLAASTTVTQDLLPR 339 Query: 364 YIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVIVIL 423 + +R+ T+ LG++ L +A VV + V Y G + +I Sbjct: 340 LRRGRGQSDNGDVHENRIATLLLGLVVLGIALVVSDVISALTVAYNLLVGG--MLIPLIG 397 Query: 424 TLFWKR-FHGKAVPPTIIAGLLFTVFWISSGLDA------KVSVRLMNFIV 467 ++WKR A+ + L VF I GLDA ++V L++F++ Sbjct: 398 AIYWKRATTAGAITSMTLGFLTVLVFMIKDGLDANTPIYYSLAVGLLSFVL 448 >pir||S75887 hypothetical protein - Synechocystis sp. (strain PCC 6803) >gi|1653432|dbj|BAA18346.1| (D90913) sodium-coupled permease [Synechocystis sp.] Length = 512 Score = 100 bits (247), Expect = 3e-20 Identities = 103/448 (22%), Positives = 191/448 (41%), Gaps = 63/448 (14%) Query: 9 AVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGFA 68 A+++ Y +I++G RK + ++ +Q+P W S AT SA LLG PG Sbjct: 7 AIVLVYSAIVIAIGAIASRKQDNTDEYFRGAKQIPWWALGFSIIATSFSAASLLGGPGEG 66 Query: 69 FAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRILG 128 + G + +G ++G + AVF + + T +Y+ +R + R LG Sbjct: 67 YGHGFLYLQLQLGDLIGYGLVIAVFLPFF----VRLNLTTAYEYLERRF---DAKTRSLG 119 Query: 129 SATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTDTV 188 S F +G VL+ L G+ +L+ +V + YTV GG+ +V +TD + Sbjct: 120 SLCFLLFVIARLGGLLYAAALVLSVLTGISTNTAILMVGVVSIIYTVAGGITAVVWTDVL 179 Query: 189 QAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAAIVFVIA 248 Q G+I++ ++A +VTA G + + G G V+ Sbjct: 180 Q-------------FGMIFVGLGAGIWA-AVTAVPGGFGELWR--IAGENGK----LVVF 219 Query: 249 EFSW------------------FFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGW-TII 289 F W F G Q R+++ D+++A+ A I +GW + + Sbjct: 220 NFDWDPASIRSLPTALIAYGILAFAVAGTNQQSVQRYVSCADEQSARKA--IFLGWFSGV 277 Query: 290 AYIGALMIGWIGIAIFG--------PNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAM 341 +GA ++ +G+ +F P +K P++++ ++ PP + + AA Sbjct: 278 LGVGATLL--LGVLLFSFYQLQGGLPGNIK-PDEILSYFIVNQVPPGASGFLVAAIFAAA 334 Query: 342 LSTADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPS-- 399 +S+ DS L +T + + YI +A +S+ V++ + G++A+ A S Sbjct: 335 MSSIDSALHSLATCMTVDFYDRYI-NIQASEMRSVRVAQGLIIVWGVVAIFSAIYAASTG 393 Query: 400 -HLIYTIVGYTWAGIGDTFSVIVILTLF 426 L+ +V YT +G + ++ LF Sbjct: 394 QDLLEFLVSYTTMFLGPLLGIFLMGVLF 421 >pir||H71097 hypothetical protein PH1044 - Pyrococcus horikoshii >gi|3257459|dbj|BAA30142.1| (AP000004) 491aa long hypothetical protein [Pyrococcus horikoshii] Length = 491 Score = 99.1 bits (243), Expect = 1e-19 Identities = 120/487 (24%), Positives = 224/487 (45%), Gaps = 34/487 (6%) Query: 9 AVLVFYLGFL---ISVGIYQGRKAK-SHKDFSIAGRQLPGWVAALSERATGE--SAWCLL 62 + L+ LG++ + VG+ G K K + + + ++GR L + L GE SA+ L Sbjct: 15 SALIIVLGWVFLSLIVGVMAGIKRKFTLEGYLVSGRTLG--LIFLYVLMAGEIYSAYAFL 72 Query: 63 GLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEK 122 G G+A++ G+ ++ AIG +A + K + + VT DY R+ K Sbjct: 73 GTGGWAYSYGMPIMY-AIGYGALAYSFGYFYARYVWKAGKAFGCVTQADYFQVRYNS--K 129 Query: 123 WIRILGSATIAFFFFFYVGAQYLGGGKVLN--TLFGLDPKLGMLITALVILPYTVMGGLK 180 + +L + F Y+ Q G G +++ +L + PK G++I ++++ Y GL+ Sbjct: 130 ALAVLVALIGIIFNIPYLQLQLQGLGYIVHVGSLGSITPKAGIVIGMIIMMIYVYTSGLR 189 Query: 181 SVAYTDTVQAIVM-ILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239 +++T+ +QA +M I+ +V + EL+ T L++ + + + Sbjct: 190 GISWTNLLQATLMFIVAWVVLFTIPFKQFGGIGELFKT-----LAQTKPDHLILHPPLGI 244 Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGW 299 + + +I FF Y PQL +D K K RN + ++ +++ Sbjct: 245 SWYVSTLILSGLGFFMY----PQLYPSIYGARDLKTLK--RNYVLLPLYSIFMIPVILAG 298 Query: 300 IGIAIFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSEN 359 +A G L P++ + + +P + V AA STA ++L+ + S+N Sbjct: 299 FTVAALGIK-LSAPDEAVLKAVEITYPSWVLGVVGAAGFAAAASTASAILLSLAGLLSKN 357 Query: 360 ILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSV 419 + I K A ++ ++VSR++ + LG++A+ +A P L+ +++ +AG+ F Sbjct: 358 LYA--IAKPTASDKELVLVSRISVILLGLLAMGLALYSPGRLV-SLLLLAYAGMTQMFPG 414 Query: 420 IVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSGLDAK---VSVRLMNFIVTFIVAIIAT 476 + LFWKR + A IIAGL+ TV ++ L + L +V IV +I Sbjct: 415 -AVFGLFWKRMNKYATGTGIIAGLI-TVAYLRLVLKKNPLGIHFGLWGLLVNIIVTLIVA 472 Query: 477 YAIKPEK 483 Y KPE+ Sbjct: 473 YLTKPEE 479 >gi|11498821 proline permease (putP-3) [Archaeoglobus fulgidus] >gi|7483927|pir||E69402 proline permease (putP-3) homolog - Archaeoglobus fulgidus >gi|2649354|gb|AAB90016.1| (AE001019) proline permease (putP-3) [Archaeoglobus fulgidus] Length = 479 Score = 98.3 bits (241), Expect = 2e-19 Identities = 116/483 (24%), Positives = 206/483 (42%), Gaps = 57/483 (11%) Query: 34 DFSIAGRQLPGWVAALSERATGESAWCLLGLPGFAFAAGLAAIWPAI-GCVLGIIVAWAV 92 DF A QL W L + S L+G+ G AF G A +W I G I + Sbjct: 3 DFVAASGQLGFWTYCLLMIGSVFSGMTLIGVAGLAFTTGYANVWERIIGPPFAIAFGTIL 62 Query: 93 FAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRILGSATIAFFFFFYVGAQYLGGGKVLN 152 +L +K +T DY+A R+ + K IRIL A F Y+ QY G V Sbjct: 63 IGYKLFNLKDKNGILTIQDYLAFRYDDP-KIIRILAGLISAVTCFVYLIGQYTAIGVVSY 121 Query: 153 TLFGLDPKLGMLITALVILPYTVMGGLKSVAYTDTVQAIVMILTLIVAPIVGVIYI---- 208 + G+ LG +I A++++ Y + GG+ S A+T +Q+I+M+L + V + ++ Sbjct: 122 VVLGIPYWLGAVIAAVIVVAYVMSGGMFSTAWTTFLQSILMLLGIYVTVPFIIAWVGGFE 181 Query: 209 ------ANHPELYATS-----------------VTAALSKAGVKYSTILGGMA---GAAA 242 A PE+ + A++ AG Y+ L G+ G Sbjct: 182 AMNQALAAMPEIQNATRGVAENFMFAKYLSKPFAPASVPLAGWVYNLTLFGITVPLGLMV 241 Query: 243 IVFVIAEFSWF----FGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIG 298 ++ F + G + I F AI A +A + +I I +L +G Sbjct: 242 APHIVNNMLTFRKIEYTRWGPLVMYVIGFSAIFLTALAGMAARVAWAKGMID-IPSLTLG 300 Query: 299 WIGIAIFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSE 358 I + K + P++ K P L + + +A ++ST D L++ ++ S Sbjct: 301 SIEV--------KWSDMAYPTIASKALPYWLFVLLLPTILAGVMSTTDRLILTAANNISY 352 Query: 359 NILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFS 418 ++L+ + KN ++ V+ L +G +L++A + P L+ + + + + F Sbjct: 353 DVLRNALGKNLSE-NALKKVNMLVVPLIGFGSLLIA-LFPQQLLAWFIWAALSLMTNCFF 410 Query: 419 VIVILTLFWKRFHGKAVPPTIIAGLLFTVFWIS--------SGLDAKVSVRLMNFIVTFI 470 ++L L+W R A ++IAG + T+ + +G+ A SV L F+ +F+ Sbjct: 411 FPIMLGLYWDRMTKNAARLSMIAGFVVTLATFAIYGKTIYIAGIPA-YSV-LPGFVASFV 468 Query: 471 VAI 473 +A+ Sbjct: 469 LAV 471 >gb|AAG20007.1| (AE005081) pantothenate permease; PanF [Halobacterium sp. NRC-1] Length = 482 Score = 97.9 bits (240), Expect = 2e-19 Identities = 104/416 (25%), Positives = 191/416 (45%), Gaps = 23/416 (5%) Query: 19 ISVGIYQGRKA-KSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGFAFAAGLAAIW 77 ++VG+ R + +D+ +AGR L V + AT SA+ P A+A G I Sbjct: 5 LAVGLVAYRVTDRDAEDYYLAGRGLGTGVLLFTTFATLLSAFTFFAGPNIAYANGPEWIL 64 Query: 78 PAIGCVLGII--VAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRILGSATIAFF 135 +G + G++ + W V R + VT + + R + +R L + F+ Sbjct: 65 -VMGLMDGVLFGLLWYVLGYRQWLLGKANGYVTLGEMLGDRF--GSRGLRGLVAGVSIFW 121 Query: 136 FFFYVGAQYLGGGKVLNTLFG--LDPKLGMLITALVILPYTVMGGLKSVAYTDTVQAIVM 193 F YV Q +G G+ L L G + G L ++ Y + G++ VA+TDT+Q + M Sbjct: 122 LFPYVMLQQIGAGEALVGLTGGAVPYWAGAGFITLFMVVYVAISGMRGVAWTDTLQGVFM 181 Query: 194 ILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAAIVFVIAEFSWF 253 + I V ++ E+ T T L+ A LGG GA + +++++ Sbjct: 182 L------GITWVAFVWVAAEIAGT--TGGLAGALPAEFRALGG--GAYSPQWMLSQAIGI 231 Query: 254 FGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALMIGWIGIAIFGPNGLKDP 313 + PQ++ RF + K I ++ ++ A ++G + P L D Sbjct: 232 AVGVSMFPQVNQRFFVADSKRTLKRTFAIWPLLVVLLFVPAFLMGAWANGVGLP--LPDG 289 Query: 314 EQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSENILKPYIYKNEADPR 373 E ++P ++ + P AA+ + GA+AAM+S++DS+L+ S+ F+ +I +P++ +A R Sbjct: 290 ENIVPILLSEYTPGWFAALVVAGALAAMMSSSDSMLLSGSSYFTRDIYRPFV-NADATAR 348 Query: 374 KSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVIVILTLFWKR 429 + + R+ + + A + + P L+ VG T G + V L ++W+R Sbjct: 349 REDTLGRVGVAAFAVAAFGGSLLRPGSLLE--VGSTAFGGFAQLAPPVALAMYWRR 402 >pir||T03475 transmembrane protein - Rhodobacter capsulatus >gi|3128276|gb|AAC16128.1| (AF010496) transmembrane protein DhlC homolog [Rhodobacter capsulatus] Length = 578 Score = 97.1 bits (238), Expect = 4e-19 Identities = 104/464 (22%), Positives = 195/464 (41%), Gaps = 39/464 (8%) Query: 8 LAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGF 67 +A+ F++ + + + + KS DF AG + G+ L+ SA LG+ Sbjct: 43 IAMFGFFVVATLFITKWAAGRTKSAADFYTAGGGITGFQNGLAIAGDYMSAASFLGISAA 102 Query: 68 AFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRIL 127 G + +IG ++G + + A RLR + TF D A P A+ +R+ Sbjct: 103 VMLQGYDGLIYSIGFLVGWPILTFLMAERLRNLGK----FTFADVAA--FPFAQTPVRVF 156 Query: 128 GSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTDT 187 + + FY+ AQ +G G+++ LFGL+ +++ ++++ Y + GG+ + + Sbjct: 157 AAMSTLVVVAFYLIAQMVGAGQLIKLLFGLEYLYAVIVVGILMMVYVLFGGMTATTWVQI 216 Query: 188 VQAIVMI-LTLIVAPIVGVIYIANHPELYATSVTA----ALSKAGVKYSTILGGMAGAAA 242 ++A +++ +A +V V Y + L+A SV AL+ G++ Sbjct: 217 IKACLLLGGASFMALMVMVHYGFSLESLFADSVKVKTDLALAAGKTPEEAAAAGISIMGP 276 Query: 243 IVFV---IAEFSW----FFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGAL 295 FV I+ S+ FG G+P + +RF + K A+ + W Y+ Sbjct: 277 GTFVKDPISAISFGMALMFG-TAGLPHILMRFFTVPSAKEARKSVMWATVWIGYFYMLTF 335 Query: 296 MIGWIGIAIFGPN-GLKDPEQVMPSVMLKLFPPALAAVFITGAV--------------AA 340 +IG+ I N GL + + + +AA+ + AV A Sbjct: 336 IIGFGAIVYVLTNPGLVSYD--AKGALTLVGGNNMAAIHLAQAVGGNIFLGFISAVAFAT 393 Query: 341 MLSTADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSH 400 +L+ L + ++ S ++ +AD L VSR+TT+ LGI+A+++ Sbjct: 394 ILAVVAGLTLSGASAVSHDLYSTVFKNGKADSASELRVSRITTICLGIVAVVLGLAFEKQ 453 Query: 401 LIYTIVGYTWAGIGDTFSVIVILTLFWKRFHGKAVPPTIIAGLL 444 I +V +A ++ ++L WK G +I G L Sbjct: 454 NIAFMVSLAFAIAASANFPVLFMSLLWK---GMTTRGAVIGGSL 494 >gi|4507035 solute carrier family 5 (sodium iodide symporter), member 5 [Homo sapiens] >gi|11526040|ref|XP_009295.1| solute carrier family 5 (sodium iodide symporter), member 5 [Homo sapiens] >gi|2136179|pir||JC4974 sodium iodide symporter - human >gi|1628579|gb|AAB17378.1| (U66088) sodium iodide symporter [Homo sapiens] >gi|3702269|gb|AAC62827.1| (AC005796) sodium iodide symporter [Homo sapiens] Length = 643 Score = 96.3 bits (236), Expect = 7e-19 Identities = 98/408 (24%), Positives = 172/408 (42%), Gaps = 49/408 (12%) Query: 12 VFYLGFLIS------VGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLP 65 VF L L+S VG+ +G + +S +DF GR+L LS A+ SA +LG+P Sbjct: 19 VFALMLLVSTGIGLWVGLARGGQ-RSAEDFFTGGRRLAALPVGLSLSASFMSAVQVLGVP 77 Query: 66 GFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIR 125 A+ GL +W +G +L ++ +F + + +Y+ R A +R Sbjct: 78 SEAYRYGLKFLWMCLGQLLNSVLTALLFMPVFYR----LGLTSTYEYLEMRFSRA---VR 130 Query: 126 ILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYT 185 + G+ Y G +LN + GLD +L T ++ YT +GG+K+V +T Sbjct: 131 LCGTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTAVGGMKAVVWT 190 Query: 186 DTVQAIVMILTLIVAPIVGVIYIA----------NHPELYATSVTAALSKAGVKYSTILG 235 D Q +VM+ V GV+ + NH + ++ ++G Sbjct: 191 DVFQVVVMLSGFWVVLARGVMLVGGPRQVLTLAQNHSRINLMDFNPDPRSRYTFWTFVVG 250 Query: 236 GMAGAAAIVFVIAEFSWFFGYLGGMPQLSI-RFMAIKDDKNAKLARNIGIGWTIIAYIGA 294 G W Y G+ Q + R++A + +K AKLA I + A Sbjct: 251 G------------TLVWLSMY--GVNQAQVQRYVACRTEKQAKLALLINQVGLFLIVSSA 296 Query: 295 LMIGWIGIAIFGP------NGLKDPEQVMPSVMLKLFP--PALAAVFITGAVAAMLSTAD 346 G + + + P+Q MP ++L +F P + +F+ A + LSTA Sbjct: 297 ACCGIVMFVFYTDCDPLLLGRISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTAS 356 Query: 347 SLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMA 394 + + + E+++KP + PRK +++S+ ++ G L +A Sbjct: 357 TSINAMAAVTVEDLIKPRL--RSLAPRKLVIISKGLSLIYGSACLTVA 402 >gi|11498804 pantothenate permease (panF-2) [Archaeoglobus fulgidus] >gi|7442767|pir||D69400 pantothenate permease (panF-2) homolog - Archaeoglobus fulgidus >gi|2649380|gb|AAB90040.1| (AE001021) pantothenate permease (panF-2) [Archaeoglobus fulgidus] Length = 474 Score = 96.0 bits (235), Expect = 9e-19 Identities = 110/444 (24%), Positives = 195/444 (43%), Gaps = 35/444 (7%) Query: 12 VFYLGFLISVGIY-QGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGFAFA 70 +++L + VG Y R KS +D+ +A R L ++ T +LG+ A+ Sbjct: 1 MYFLVTTLGVGFYLMKRMEKSEEDYLVAKRGLGAVPVGVTLALTVLGTPHILGVMESAYD 60 Query: 71 AGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRILGSA 130 GL A+W + + + + +F GR ++ + F+D I + W+R++ A Sbjct: 61 IGLPAVWFSFAHAIMLAIV-CLFTGRWARKLKVESVPEFLDVIFSNY-----WLRLMVGA 114 Query: 131 TIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTDTVQA 190 IA F + G G ++ L G ++G++I AL+ + Y V+ G+K VA+ + + A Sbjct: 115 VIAGAIFGICTLETQGLGVFVSILTGTSIEVGIVIGALIGILYVVLSGMKEVAWLNVLNA 174 Query: 191 IVMILTLIVAPIVGVIYIANH----PELYATSVTAALSKAGVKYSTILGGMAGAAAIVFV 246 +++ + +I A V + N E Y ++ A + +G A+V V Sbjct: 175 VILYIGIIAATFVLGSGLQNGWEGVNEFYISNDLAGKLNIFGSWEVFVG-----FALVNV 229 Query: 247 IAEFSWFFGYLGGMPQLSIR-FMAIKDDKNAKLARNIGIGWTIIAYIGALMIGWIGIAI- 304 +A + G+ Q + +A K + A I + + A ++G A Sbjct: 230 LATV-----FFQGISQQGLHAALAAKSPDVLRKAMLIAVPVNGSFAVFAAVMGMAARATP 284 Query: 305 -FGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSENILKP 363 F G K P++++ + P +A+ + + A+LS+ L+ +T F +I K Sbjct: 285 EFAELGAK---TATPAMIVSVLPTWASALLLATCLVAVLSSYAITLLAPTTIFVNDIYKA 341 Query: 364 YIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVIVIL 423 + K A + L +SR+ TV L + ALI A +P L + ++W F VI Sbjct: 342 -VLKPNASHEELLRLSRILTVLLAVAALIPAVSLPPILAAMMWLFSWLVPVFWF---VIF 397 Query: 424 TLFWKRFHGKAVPPTIIAGLLFTV 447 LFWKR + P II LL V Sbjct: 398 GLFWKR----SAPAAIITCLLVWV 417 >dbj|BAA24835.1| (D87920) sodium iodide symporter [Homo sapiens] Length = 643 Score = 96.0 bits (235), Expect = 9e-19 Identities = 98/408 (24%), Positives = 172/408 (42%), Gaps = 49/408 (12%) Query: 12 VFYLGFLIS------VGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLP 65 VF L L+S VG+ +G + +S +DF GR+L LS A+ SA +LG+P Sbjct: 19 VFALMLLVSTGIGLWVGLARGGQ-RSAEDFFTGGRRLAALPVGLSLSASFMSAVQVLGVP 77 Query: 66 GFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIR 125 A+ GL +W +G +L ++ +F + + +Y+ R A +R Sbjct: 78 SEAYRYGLKFLWMCLGQLLNSVLTPLLFMPVFYR----LGLTSTYEYLEMRFSRA---VR 130 Query: 126 ILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYT 185 + G+ Y G +LN + GLD +L T ++ YT +GG+K+V +T Sbjct: 131 LCGTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTAVGGMKAVVWT 190 Query: 186 DTVQAIVMILTLIVAPIVGVIYIA----------NHPELYATSVTAALSKAGVKYSTILG 235 D Q +VM+ V GV+ + NH + ++ ++G Sbjct: 191 DVFQVVVMLSGFWVVLARGVMLVGGPRQVLTLAQNHSRINLMDFNPDPRSRYTFWTFVVG 250 Query: 236 GMAGAAAIVFVIAEFSWFFGYLGGMPQLSI-RFMAIKDDKNAKLARNIGIGWTIIAYIGA 294 G W Y G+ Q + R++A + +K AKLA I + A Sbjct: 251 G------------TLVWLSMY--GVNQAQVQRYVACRTEKQAKLALLINQVGLFLIVSSA 296 Query: 295 LMIGWIGIAIFGP------NGLKDPEQVMPSVMLKLFP--PALAAVFITGAVAAMLSTAD 346 G + + + P+Q MP ++L +F P + +F+ A + LSTA Sbjct: 297 ACCGIVMFVFYTDCDPLLLGRISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTAS 356 Query: 347 SLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMA 394 + + + E+++KP + PRK +++S+ ++ G L +A Sbjct: 357 TSINAMAAVTVEDLIKPRL--RSLAPRKLVIISKGLSLIYGSACLTVA 402 >emb|CAB88444.1| (AL353815) putative sodium-coupled permease [Streptomyces coelicolor A3(2)] Length = 527 Score = 95.2 bits (233), Expect = 2e-18 Identities = 113/505 (22%), Positives = 213/505 (41%), Gaps = 56/505 (11%) Query: 9 AVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGFA 68 +VL+ Y ++++G++ ++ DF AG ++P W++ +S +G SA G G A Sbjct: 7 SVLIGYFAVMVAIGVWSHKRVDDVSDFFTAGGKMPWWLSGISHHMSGYSAVMFTGYAGIA 66 Query: 69 FAAGLAAI--WPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRH----PEAEK 122 + G+ + W + LG+ + +FA R+ + + + ++Y+ R+ +A Sbjct: 67 YTYGVTSFVTW-SFPIALGVAIGSKLFAPRINRLRSRLHVASPLEYLKNRYNLPTQQALA 125 Query: 123 WIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSV 182 W +L V A++ +L+ G+ G+LIT ++ Y +GGL + Sbjct: 126 WSGML-------LKIVDVAAKWAAIATLLSVFTGITLNQGILITGVITGIYCTIGGLWAD 178 Query: 183 AYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAA 242 A T+ Q I+ +L + + V+ + +H + AL G + G Sbjct: 179 ALTELGQFIIQLLAGVAMFVAVVMKLGDHGGFFGVWDEPALQGHGKP-------LVGPYG 231 Query: 243 IVFVIA-EFSWFFGYLGGMPQLSIRFMAIKD----DKNAKLARNIGIGWTIIAYIGALMI 297 VF++A F F Y GGM + R+MA + + A+L+ + + W ++ + M Sbjct: 232 TVFLLAFLFIKLFEYNGGMLNQAQRYMATANAREATRGARLSAVLWLVWPLVLFFPMWM- 290 Query: 298 GWIGIAIFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFS 357 + + D + +L P L + I G + ++ S + F+ Sbjct: 291 ----SPLLVESQKADGSDSYALMTEQLLPHGLLGLVIVGFFSHTMAMCSSDANAIAAVFT 346 Query: 358 ENILKPYIYKNEA--DPRKSLMVSRLTTVSLGIIALIMAYVVPSHL---IYTIVGYTWAG 412 ++ P + K R L+ +RLTTV +++ +A V S I T+V AG Sbjct: 347 RDV-APVLSKRARGWGQRSGLLAARLTTVIFLGLSMAVATQVDSPTFKDIITVVIKWVAG 405 Query: 413 IGDTFSVIVILTLFWKRFHGKAVPPTIIA--GLLFTVFWISS-----------GLDAKVS 459 + ++ ++L L R ++ P + GL FW+ + L+ +VS Sbjct: 406 LMGPIAIPMMLGLL--RPFRRSGPTAALTSWGLGLVAFWLVNYPINWSVDGGVPLEYQVS 463 Query: 460 VRLMNFIVTFIVAIIATYAIKPEKT 484 V L +V IA +KPE T Sbjct: 464 VPL----AVSLVLYIAIGYLKPEDT 484 >emb|CAC17810.1| (AJ276242) sodium iodide symporter [Sus scrofa] Length = 643 Score = 94.8 bits (232), Expect = 2e-18 Identities = 110/475 (23%), Positives = 200/475 (41%), Gaps = 64/475 (13%) Query: 12 VFYLGFLIS------VGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLP 65 VF L L+S VG+ +G + +S +DF GR+L LS A+ SA +LG+P Sbjct: 19 VFALMLLVSTGIGLWVGLARGGQ-RSAEDFFTGGRRLTAVPVGLSLSASFMSAVQVLGVP 77 Query: 66 GFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIR 125 A+ GL +W +G +L ++ +F + + Y+ R A +R Sbjct: 78 AEAYRYGLKFLWMCLGQLLNSLLTALLFLPVFYR----LGLTSTYQYLELRFSRA---VR 130 Query: 126 ILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYT 185 + G+ Y G +LN + GLD +L T ++ YT +GG+K+V +T Sbjct: 131 LCGTLQYLVATMLYTGVVIYAPALILNQVTGLDIWASLLSTGIICTFYTTVGGMKAVIWT 190 Query: 186 DTVQAIVMILTLIVAPIVGVIYIA----------NHPELYATSVTAALSKAGVKYSTILG 235 D Q +VM+ V G + + NH + + ++ ++G Sbjct: 191 DVFQVLVMLTGFWVVLARGTVLVGGPGRVLELAKNHSRINLMDFDLDPRRRYTFWTFVVG 250 Query: 236 GMAGAAAIVFVIAEFSWFFGYLGGMPQLSI-RFMAIKDDKNAKLARNIGIGWTIIAYIGA 294 G W Y G+ Q + R++A + +K AKLA I + A Sbjct: 251 G------------TLVWLSMY--GVNQAQVQRYVACRTEKQAKLALLINQVGLFLIVSSA 296 Query: 295 LMIGWIGIAIFG------PNGLKDPEQVMPSVMLKLFP--PALAAVFITGAVAAMLSTAD 346 G + A++ + P+Q MP ++L +F P + +F+ A + LSTA Sbjct: 297 AACGIVMFALYVDCDPLLAGHISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTAS 356 Query: 347 SLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLI---- 402 + + + E+++KP + PR+ +++S+ ++ G L +A + S L+ Sbjct: 357 TSINAMAAVTVEDLIKPRL--PNLAPRRLVIISKGLSLIYGSACLTVAAL--SSLLGGGV 412 Query: 403 ----YTIVGYTWAGIGDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453 +T++G + F +L +F + V + AGL ++ W++ G Sbjct: 413 LQGSFTVMGVISGPLLGAF----VLGMFLPSCNTSGVLSGLAAGLALSL-WVAVG 462 >emb|CAC17816.1| (AJ276292) sodium iodide symporter [Sus scrofa] Length = 636 Score = 94.8 bits (232), Expect = 2e-18 Identities = 110/475 (23%), Positives = 200/475 (41%), Gaps = 64/475 (13%) Query: 12 VFYLGFLIS------VGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLP 65 VF L L+S VG+ +G + +S +DF GR+L LS A+ SA +LG+P Sbjct: 19 VFALMLLVSTGIGLWVGLARGGQ-RSAEDFFTGGRRLTAVPVGLSLSASFMSAVQVLGVP 77 Query: 66 GFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIR 125 A+ GL +W +G +L ++ +F + + Y+ R A +R Sbjct: 78 AEAYRYGLKFLWMCLGQLLNSLLTALLFLPVFYR----LGLTSTYQYLELRFSRA---VR 130 Query: 126 ILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYT 185 + G+ Y G +LN + GLD +L T ++ YT +GG+K+V +T Sbjct: 131 LCGTLQYLVATMLYTGVVIYAPALILNQVTGLDIWASLLSTGIICTFYTTVGGMKAVIWT 190 Query: 186 DTVQAIVMILTLIVAPIVGVIYIA----------NHPELYATSVTAALSKAGVKYSTILG 235 D Q +VM+ V G + + NH + + ++ ++G Sbjct: 191 DVFQVLVMLTGFWVVLARGTVLVGGPGRVLELAKNHSRINLMDFDLDPRRRYTFWTFVVG 250 Query: 236 GMAGAAAIVFVIAEFSWFFGYLGGMPQLSI-RFMAIKDDKNAKLARNIGIGWTIIAYIGA 294 G W Y G+ Q + R++A + +K AKLA I + A Sbjct: 251 G------------TLVWLSMY--GVNQAQVQRYVACRTEKQAKLALLINQVGLFLIVSSA 296 Query: 295 LMIGWIGIAIFG------PNGLKDPEQVMPSVMLKLFP--PALAAVFITGAVAAMLSTAD 346 G + A++ + P+Q MP ++L +F P + +F+ A + LSTA Sbjct: 297 AACGIVMFALYVDCDPLLAGHISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTAS 356 Query: 347 SLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLI---- 402 + + + E+++KP + PR+ +++S+ ++ G L +A + S L+ Sbjct: 357 TSINAMAAVTVEDLIKPRL--PNLAPRRLVIISKGLSLIYGSACLTVAAL--SSLLGGGV 412 Query: 403 ----YTIVGYTWAGIGDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453 +T++G + F +L +F + V + AGL ++ W++ G Sbjct: 413 LQGSFTVMGVISGPLLGAF----VLGMFLPSCNTSGVLSGLAAGLALSL-WVAVG 462 >gi|11141885 solute carrier family 5 (choline transporter), member 7; high affinity choline transporter; hemicholinium-3-sensitive choline transporter [Homo sapiens] >gi|9843754|emb|CAC03717.1| (AJ401466) high affinity choline transporter [Homo sapiens] >gi|10998442|gb|AAG25940.1| (AF276871) high affinity choline transporter [Homo sapiens] >gi|11231081|dbj|BAB18161.1| (AB043997) high-affinity choline transporter CHT1 [Homo sapiens] Length = 580 Score = 92.4 bits (226), Expect = 1e-17 Identities = 102/434 (23%), Positives = 188/434 (42%), Gaps = 58/434 (13%) Query: 7 ILAVLVFYLGFLISVGIYQGRKAKSH-------KDFSIAGRQLPGWVAALSERATGESAW 59 ++A++VFYL L+ VGI+ + K+ + + GR + V + AT Sbjct: 8 LIAIIVFYLLILL-VGIWAAWRTKNSGSAEERSEAIIVGGRDIGLLVGGFTMTATWVGGG 66 Query: 60 CLLGLPGFAFAAGLAAIWPA--IGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRH 117 + G + G W IG L +I+ FA +R + F KR Sbjct: 67 YINGTAEAVYVPGYGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQIYGKRM 126 Query: 118 PEAEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMG 177 ++G F+ A + G ++ + +D + ++I+AL+ YT++G Sbjct: 127 GGLLFIPALMGE-------MFWAAAIFSALGATISVIIDVDMHISVIISALIATLYTLVG 179 Query: 178 GLKSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGM 237 GL SVAYTD VQ + + V + V + +HP + TA KY G Sbjct: 180 GLYSVAYTDVVQ----LFCIFVGLWISVPFALSHPAVADIGFTA----VHAKYQKPWLGT 231 Query: 238 AGAAAIVFVIAEFSWFFGY----LGGMPQLSI--RFMAIKDDKNAKLARNIGIGWTIIAY 291 ++ + +SW + LGG+P + R ++ A++ + ++ Sbjct: 232 VDSSEV------YSWLDSFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMA 285 Query: 292 IGALMIGWIGIA---------IFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAV-AAM 341 I A++IG IG + + P ++ + ++P ++L+ P + F GAV AA+ Sbjct: 286 IPAILIGAIGASTDWNQTAYGLPDPKTTEEADMILP-IVLQYLCPVYISFFGLGAVSAAV 344 Query: 342 LSTADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMA------- 394 +S+ADS ++ +S+ F+ NI + +N +D ++ + V R+T G A MA Sbjct: 345 MSSADSSILSASSMFARNIYQLSFRQNASD-KEIVWVMRITVFVFGASATAMALLTKTVY 403 Query: 395 --YVVPSHLIYTIV 406 + + S L+Y ++ Sbjct: 404 GLWYLSSDLVYIVI 417 >sp|P96169|SGLT_VIBPA SODIUM/GLUCOSE COTRANSPORTER (NA(+)/GLUCOSE SYMPORTER) >gi|8886895|gb|AAF80602.1|AF255301_1 (AF255301) Na+/galactose cotransporter SGLT [Vibrio parahaemolyticus] Length = 543 Score = 92.1 bits (225), Expect = 1e-17 Identities = 112/470 (23%), Positives = 192/470 (40%), Gaps = 42/470 (8%) Query: 8 LAVLVFYLGFLISVGIYQGRKAK----SHKDFSIAGRQLPGWVAALSERATGESAWCLLG 63 + V Y+ +I VG++ R K S +D+ +AG+ LP W S A SA +G Sbjct: 13 IMVFAIYVAIIIGVGLWVSRDKKGTQKSTEDYFLAGKSLPWWAVGASLIAANISAEQFIG 72 Query: 64 LPGFAFAAGLA-AIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEK 122 + G ++ GLA A + + + IIV + K T +++ KR + K Sbjct: 73 MSGSGYSIGLAIASYEWMSAITLIIVGKYFLPIFIEK-----GIYTIPEFVEKRFNKKLK 127 Query: 123 WIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSV 182 IL I+ + F + + GG L T+ G+ +L AL L Y++ GGL +V Sbjct: 128 --TILAVFWISLYIFVNLTSVLYLGGLALETILGIPLMYSILGLALFALVYSIYGGLSAV 185 Query: 183 AYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILG------- 235 +TD +Q ++L + + V +I +A V+ + A + IL Sbjct: 186 VWTDVIQVFFLVLGGFMTTYMAVSFIGGTDGWFA-GVSKMVDAAPGHFEMILDQSNPQYM 244 Query: 236 GMAGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAK---------------LAR 280 + G A ++ + + + Y G + R +A K A+ L Sbjct: 245 NLPGIAVLIGGLWVANLY--YWGFNQYIIQRTLAAKSVSEAQKGIVFAAFLKLIVPFLVV 302 Query: 281 NIGIGWTIIAYIGALMIGWIGIAIFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAA 340 GI +I LM IA + ++ P + + P + V AA Sbjct: 303 LPGIAAYVITSDPQLMASLGDIAATNLPSAANADKAYP-WLTQFLPVGVKGVVFAALAAA 361 Query: 341 MLSTADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVP-- 398 ++S+ S+L ++T F+ +I K YI + D K + V R V IIA ++A ++ Sbjct: 362 IVSSLASMLNSTATIFTMDIYKEYISPDSGD-HKLVNVGRTAAVVALIIACLIAPMLGGI 420 Query: 399 SHLIYTIVGYTWAGIGDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVF 448 I YT + + +L LFWK+ K ++A + F +F Sbjct: 421 GQAFQYIQEYTGL-VSPGILAVFLLGLFWKKTTSKGAIIGVVASIPFALF 469 >dbj|BAA11215.1| (D78137) Na+/glucose symporter [Vibrio parahaemolyticus] Length = 530 Score = 91.7 bits (224), Expect = 2e-17 Identities = 112/468 (23%), Positives = 191/468 (39%), Gaps = 42/468 (8%) Query: 10 VLVFYLGFLISVGIYQGRKAK----SHKDFSIAGRQLPGWVAALSERATGESAWCLLGLP 65 V Y+ +I VG++ R K S +D+ +AG+ LP W S A SA +G+ Sbjct: 2 VFAIYVAIIIGVGLWVSRDKKGTQKSTEDYFLAGKSLPWWAVGASLIAANISAEQFIGMS 61 Query: 66 GFAFAAGLA-AIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWI 124 G ++ GLA A + + + IIV + K T +++ KR + K Sbjct: 62 GSGYSIGLAIASYEWMSAITLIIVGKYFLPIFIEK-----GIYTIPEFVEKRFNKKLK-- 114 Query: 125 RILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAY 184 IL I+ + F + + GG L T+ G+ +L AL L Y++ GGL +V + Sbjct: 115 TILAVFWISLYIFVNLTSVLYLGGLALETILGIPLMYSILGLALFALVYSIYGGLSAVVW 174 Query: 185 TDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILG-------GM 237 TD +Q ++L + + V +I +A V+ + A + IL + Sbjct: 175 TDVIQVFFLVLGGFMTTYMAVSFIGGTDGWFA-GVSKMVDAAPGHFEMILDQSNPQYMNL 233 Query: 238 AGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAK---------------LARNI 282 G A ++ + + + Y G + R +A K A+ L Sbjct: 234 PGIAVLIGGLWVANLY--YWGFNQYIIQRTLAAKSVSEAQKGIVFAAFLKLIVPFLVVLP 291 Query: 283 GIGWTIIAYIGALMIGWIGIAIFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAML 342 GI +I LM IA + ++ P + + P + V AA++ Sbjct: 292 GIAAYVITSDPQLMASLGDIAATNLPSAANADKAYP-WLTQFLPVGVKGVVFAALAAAIV 350 Query: 343 STADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVP--SH 400 S+ S+L ++T F+ +I K YI + D K + V R V IIA ++A ++ Sbjct: 351 SSLASMLNSTATIFTMDIYKEYISPDSGD-HKLVNVGRTAAVVALIIACLIAPMLGGIGQ 409 Query: 401 LIYTIVGYTWAGIGDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVF 448 I YT + + +L LFWK+ K ++A + F +F Sbjct: 410 AFQYIQEYTGL-VSPGILAVFLLGLFWKKTTSKGAIIGVVASIPFALF 456 >gi|11528510 solute carrier family 5 (choline transporter), member 7 [Mus musculus] >gi|9843809|emb|CAC03719.1| (AJ401467) high affinity choline transporter [Mus musculus] Length = 580 Score = 91.7 bits (224), Expect = 2e-17 Identities = 110/467 (23%), Positives = 202/467 (42%), Gaps = 55/467 (11%) Query: 7 ILAVLVFYLGFLISVGIYQGRKAKS------HKD-FSIAGRQLPGWVAALSERATGESAW 59 ++A+++FYL + VGI+ K K+ H + + GR + V + AT Sbjct: 8 LVAIILFYL-LIFLVGIWAAWKTKNSGNPEEHSEAIIVGGRDIGLLVGGFTMTATWVGGG 66 Query: 60 CLLGLPGFAFAAGLAAIWPA--IGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRH 117 + G + G W IG L +I+ FA +R + F KR Sbjct: 67 YINGTAVAVYGPGCGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQIYGKRM 126 Query: 118 PEAEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMG 177 ++G F+ A + G ++ + +D + ++++AL+ + YT++G Sbjct: 127 GGLLFIPALMGE-------MFWAAAIFSALGATISVIIDVDVNISVIVSALIAILYTLVG 179 Query: 178 GLKSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGM 237 GL SVAYTD VQ + + L ++ V + +HP + TA +K S LG + Sbjct: 180 GLYSVAYTDVVQLFCIFIGLWIS----VPFALSHPAVTDIGFTAVHAK---YQSPWLGTI 232 Query: 238 AGAAAIVFVIAEFSWFFGY----LGGMPQLSI--RFMAIKDDKNAKLARNIGIGWTIIAY 291 + ++W + LGG+P + R ++ A++ + ++ Sbjct: 233 ES-------VEVYTWLDNFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSYLAAFGCLVMA 285 Query: 292 IGALMIGWIGIA------IFG---PNGLKDPEQVMPSVMLKLFPPALAAVFITGAV-AAM 341 + A+ IG IG + +G P ++ + ++P ++L+ P + F GAV AA+ Sbjct: 286 LPAICIGAIGASTDWNQTAYGYPDPKTKEEADMILP-IVLQYLCPVYISFFGLGAVSAAV 344 Query: 342 LSTADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHL 401 +S+ADS ++ +S+ F+ NI + +N +D ++ + V R+T + G A MA L Sbjct: 345 MSSADSSILSASSMFARNIYQLSFRQNASD-KEIVWVMRITVLVFGASATAMAL-----L 398 Query: 402 IYTIVGYTWAGIGDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVF 448 T+ G W D +I+ L F +AG +F +F Sbjct: 399 TKTVYG-LWYLSSDLVYIIIFPQLLCVLFIKGTNTYGAVAGYIFGLF 444 >gb|AAG36945.1| (AF276872) sodium and chloride-dependent high-affinity choline transporter [Mus musculus] Length = 580 Score = 91.3 bits (223), Expect = 2e-17 Identities = 109/467 (23%), Positives = 201/467 (42%), Gaps = 55/467 (11%) Query: 7 ILAVLVFYLGFLISVGIYQGRKAKSHKD-------FSIAGRQLPGWVAALSERATGESAW 59 ++A+++FYL + VGI+ K K+ + + GR + V + AT Sbjct: 8 LVAIILFYL-LIFLVGIWAAWKTKNSGNPEERSEAIIVGGRDIGLLVGGFTMTATWVGGG 66 Query: 60 CLLGLPGFAFAAGLAAIWP--AIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRH 117 + G + G W IG L +I+ FA +R + F KR Sbjct: 67 YINGTAEAVYGPGCGLAWAHAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFKQIYGKRM 126 Query: 118 PEAEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMG 177 ++G F+ A + G ++ + +D + ++++AL+ + YT++G Sbjct: 127 GGLLFIPALMGE-------MFWAAAIFSALGATISVIIDVDVNISVIVSALIAILYTLVG 179 Query: 178 GLKSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGM 237 GL SVAYTD VQ + + L ++ V + +HP + TA +K S LG + Sbjct: 180 GLYSVAYTDVVQLFCIFIGLWIS----VPFALSHPAVTDIGFTAVHAK---YQSPWLGTI 232 Query: 238 AGAAAIVFVIAEFSWFFGY----LGGMPQLSI--RFMAIKDDKNAKLARNIGIGWTIIAY 291 + ++W + LGG+P + R ++ A++ + ++ Sbjct: 233 ES-------VEVYTWLDNFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMA 285 Query: 292 IGALMIGWIGIA------IFG---PNGLKDPEQVMPSVMLKLFPPALAAVFITGAV-AAM 341 + A+ IG IG + +G P ++ + ++P ++L+ P + F GAV AA+ Sbjct: 286 LPAICIGAIGASTDWNQTAYGYPDPKTKEEADMILP-IVLQYLCPVYISFFGLGAVSAAV 344 Query: 342 LSTADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHL 401 +S+ADS ++ +S+ F+ NI + +N +D ++ + V R+T + G A MA L Sbjct: 345 MSSADSSILSASSMFARNIYQLSFRQNASD-KEIVWVMRITVLVFGASATAMAL-----L 398 Query: 402 IYTIVGYTWAGIGDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVF 448 T+ G W D +I+ L F +AG +F +F Sbjct: 399 TKTVYG-LWYLSSDLVYIIIFPQLLCVLFIKGTNTYGAVAGYIFGLF 444 >dbj|BAA90483.1| (AB030946) high-affinity choline transporter CHO-1 [Caenorhabditis elegans] Length = 576 Score = 90.9 bits (222), Expect = 3e-17 Identities = 102/426 (23%), Positives = 185/426 (42%), Gaps = 62/426 (14%) Query: 7 ILAVLVFYLGFLISVGIYQGRKAKSHKDFS-----------IAGRQLPGWVAALSERATG 55 I+A++ FY+ L+ VGI+ GRK+KS K+ +AGR + V + AT Sbjct: 7 IVAIVFFYVLILV-VGIWAGRKSKSSKELESEAGAATEEVMLAGRNIGTLVGIFTMTATW 65 Query: 56 ESAWCLLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAK 115 + G + GL +G + +++ +FA ++R+E YI Sbjct: 66 VGGAYINGTAEALYNGGLLGCQAPVGYAISLVMGGLLFAKKMREEG----------YITM 115 Query: 116 RHPEAEKWIRILGSATIAFFFF---FYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILP 172 P K+ + +G F+ A G L+ + G+D + ++A + + Sbjct: 116 LDPFQHKYGQRIGGLMYVPALLGETFWTAAILSALGATLSVILGIDMNASVTLSACIAVF 175 Query: 173 YTVMGGLKSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYST 232 YT GG +VAYTD VQ + + L V +++ +S+ + Sbjct: 176 YTFTGGYYAVAYTDVVQLFCIFVGLWVCVPAAMVH----------DGAKDISRNAGDWIG 225 Query: 233 ILGGMAGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNI----GIGWTI 288 +GG + + + GG+P + F + K A A+ + G+G + Sbjct: 226 EIGGFKETSLWIDCM-----LLLVFGGIP-WQVYFQRVLSSKTAHGAQTLSFVAGVGCIL 279 Query: 289 IAYIGALMIGWIG------IAIFGP--NGLK----DPEQ---VMPSVMLKLFPPALAAVF 333 +A I +IG I + + P NG K P++ V+P V L P +A + Sbjct: 280 MA-IPPALIGAIARNTDWRMTDYSPWNNGTKVESIPPDKRNMVVPLVFQYLTPRWVAFIG 338 Query: 334 ITGAVAAMLSTADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIM 393 + AA++S+ADS ++ +++ F+ NI K I + A ++ ++V R+ + +GI+A IM Sbjct: 339 LGAVSAAVMSSADSSVLSAASMFAHNIWKLTI-RPHASEKEVIIVMRIAIICVGIMATIM 397 Query: 394 AYVVPS 399 A + S Sbjct: 398 ALTIQS 403 >dbj|BAA90484.1| (AB030947) high-affinity choline transporter CHT1 [Rattus norvegicus] Length = 580 Score = 90.5 bits (221), Expect = 4e-17 Identities = 109/467 (23%), Positives = 200/467 (42%), Gaps = 55/467 (11%) Query: 7 ILAVLVFYLGFLISVGIYQGRKAKSHKDFS-------IAGRQLPGWVAALSERATGESAW 59 ++A+++FYL + VGI+ K K+ + + GR + V + AT Sbjct: 8 LVAIILFYL-LIFLVGIWAAWKTKNSGNAEERSEAIIVGGRDIGLLVGGFTMTATWVGGG 66 Query: 60 CLLGLPGFAFAAGLAAIWPA--IGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRH 117 + G + G W IG L +I+ FA +R + F KR Sbjct: 67 YINGTAEAVYGPGCGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQIYGKRM 126 Query: 118 PEAEKWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMG 177 ++G F+ A + G ++ + +D + ++++AL+ + YT++G Sbjct: 127 GGLLFIPALMGE-------MFWAAAIFSALGATISVIIDVDVNISVIVSALIAILYTLVG 179 Query: 178 GLKSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGM 237 GL SVAYTD VQ + + L ++ V + +HP + TA +K S LG + Sbjct: 180 GLYSVAYTDVVQLFCIFIGLWIS----VPFALSHPAVTDIGFTAVHAK---YQSPWLGTI 232 Query: 238 AGAAAIVFVIAEFSWFFGY----LGGMPQLSI--RFMAIKDDKNAKLARNIGIGWTIIAY 291 + ++W + LGG+P + R ++ A++ + ++ Sbjct: 233 ES-------VEVYTWLDNFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMA 285 Query: 292 IGALMIGWIGIA------IFG---PNGLKDPEQVMPSVMLKLFPPALAAVFITGAV-AAM 341 + A+ IG IG + +G P ++ + ++P ++L+ P + F GAV AA+ Sbjct: 286 LPAICIGAIGASTDWNQTAYGFPDPKTKEEADMILP-IVLQYLCPVYISFFGLGAVSAAV 344 Query: 342 LSTADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHL 401 +S+ADS ++ +S+ F+ NI + +N +D ++ + V R+T G A MA L Sbjct: 345 MSSADSSILSASSMFARNIYQLSFRQNASD-KEIVWVMRITVFVFGASATAMAL-----L 398 Query: 402 IYTIVGYTWAGIGDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVF 448 T+ G W D +I+ L F +AG +F +F Sbjct: 399 TKTVYG-LWYLSSDLVYIIIFPQLLCVLFIKGTNTYGAVAGYIFGLF 444 >emb|CAB95932.1| (AL359989) putative sodium:solute symporter [Streptomyces coelicolor A3(2)] Length = 562 Score = 87.8 bits (214), Expect = 3e-16 Identities = 103/482 (21%), Positives = 192/482 (39%), Gaps = 47/482 (9%) Query: 10 VLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGFAF 69 +L Y ++ +G R ++ DF ++GR LP WV L+ A A +LG+ + Sbjct: 25 ILGIYFVVVLGIGFAARRSVRTSLDFFLSGRSLPAWVTGLAFVAANLGATEILGMAANSA 84 Query: 70 AAGLAAI-WPAIGCV-----LGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKW 123 G+ W IG + LG+++ + ++R E ++ R +A Sbjct: 85 QYGVYTTHWYWIGAIPAMVFLGLVMMPFYYGSKVRSVPE---------FLLLRFDKAS-- 133 Query: 124 IRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVA 183 +L SA A G V+ L G + +++ +L Y +GGL S Sbjct: 134 -HLLSSALFAIAAILIAGVNLYALAIVVEALLGWPEWVAIVVAGFFVLAYITLGGLSSAI 192 Query: 184 YTDTVQAIVMILTLIVAPIVGVIYIANHPEL-------YATSVTAALSKAGVKYSTILGG 236 Y + +Q V++ LI I+G+ + L + + A G+ LG Sbjct: 193 YNEVLQFFVILAGLIPITILGLKKVGGWDGLSDSLSKSHGSDFMTAWGGTGIGSENPLGA 252 Query: 237 --MAGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGA 294 + + FV++ W + LS + ++ + +A I + I Sbjct: 253 NWLTIVLGLGFVLSFGYWTTNFAEVQRALSAKNLSAA-QRTPLIAAFPKIFIVFVVMIPG 311 Query: 295 LMIGWIGIAIFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSST 354 L+ + I P +P +M +L P + + +TG +AA ++ + + +T Sbjct: 312 LVAAVLVPKIGTPGSDLQYNDAIPYLMQQLLPNGVLGIAVTGLLAAFMAGMAANISSFNT 371 Query: 355 EFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHL--IYTIVGYTWAG 412 F+ +I + Y+ K+ D + RL TV +G++A I + S I + + ++ Sbjct: 372 VFTTDIWQKYVVKDRED-GYYVRFGRLITV-IGVLASIGTAFLASSFSNIMSYLQTLFSF 429 Query: 413 IGDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSGLDAKVSVRLMNFIVTFIVA 472 V+ I+ +FWKR K + FW GL A + ++N+ V + Sbjct: 430 FNVPMFVVFIIGMFWKRASMK------------SGFW---GLIAGTTAAMVNYFVIYKQG 474 Query: 473 II 474 II Sbjct: 475 II 476 >prf||2204393A Na/I symporter [Rattus norvegicus] Length = 618 Score = 86.6 bits (211), Expect = 6e-16 Identities = 96/404 (23%), Positives = 164/404 (39%), Gaps = 43/404 (10%) Query: 10 VLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGFAF 69 +L+ G + VG+ +G + +S DF GRQL LS A+ SA +LG+P A Sbjct: 23 MLLVSTGIGLMVGLARGGQ-RSADDFFTGGRQLAAVPVGLSLAASFMSAVQVLGVPAEAA 81 Query: 70 AAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRILGS 129 GL +W G +L ++ +F + + Y+ R A +R+ G+ Sbjct: 82 RYGLKFLWMCAGQLLNSLLTAFLFLPIFYR----LGLTSTYQYLELRFSRA---VRLCGT 134 Query: 130 ATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTDTVQ 189 Y G +LN + GLD +L T ++ YT +GG+K+V +TD Q Sbjct: 135 LQYLVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTLYTTVGGMKAVVWTDVFQ 194 Query: 190 AIVMILTLIVAPIVGVIYIA----------NHPELYATSVTAALSKAGVKYSTILGGMAG 239 +VM++ V GVI + NH + ++ +GG Sbjct: 195 VVVMLVGFWVILARGVILLGGPRNVLSLAQNHSRINLMDFDPDPRSRYTFWTFYVGG--- 251 Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSI-RFMAIKDDKNAKLARNIGIGWTIIAYIGALMIG 298 W Y G+ Q + R++A + AKLA + + A G Sbjct: 252 ---------TLVWLSMY--GVNQAQVQRYVACHTEGKAKLALLVNQLGLFLIVASAACCG 300 Query: 299 WIGIAIFG------PNGLKDPEQVMPSVMLKLFP--PALAAVFITGAVAAMLSTADSLLI 350 + + + P+Q MP ++L +F P + +F+ AV+ LSTA + + Sbjct: 301 IVMFVYYKDCDPLLTGRISAPDQYMPLLVLDIFEDLPGVPGLFLACAVSGTLSTASTSIN 360 Query: 351 LSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMA 394 + E+++KP + PRK + +S+ + G L +A Sbjct: 361 AMAAVTVEDLIKPRM--PGLAPRKLVFISKGLSFIYGSACLTVA 402 >gi|10863879 solute carrier family 5 (sodium-dependent vitamin transporter), member 6 [Homo sapiens] >gi|4884550|gb|AAD31727.1|AF069307_1 (AF069307) sodium-dependent multivitamin transporter [Homo sapiens] >gi|5006365|gb|AAD37481.1|AF081571_1 (AF081571) sodium-dependent multi-vitamin transporter [Homo sapiens] >gi|5006439|gb|AAD37502.1| (AF116241) sodium-dependent multivitamin transporter [Homo sapiens] Length = 635 Score = 86.6 bits (211), Expect = 6e-16 Identities = 115/469 (24%), Positives = 196/469 (41%), Gaps = 51/469 (10%) Query: 10 VLVFYLGFLISVGIY---QGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPG 66 V V L +++G+Y +G + + +A R++ ALS AT +SA +LG+P Sbjct: 31 VFVLLLVLSLAIGLYHACRGWGRHTVGELLMADRKMGCLPVALSLLATFQSAVAILGVPS 90 Query: 67 FAFAAGLAAIWPAIGCV--LGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWI 124 + G W +GC LG+++ +F + + +Y+ R K + Sbjct: 91 EIYRFG-TQYW-FLGCCYFLGLLIPAHIFIPVFYR----LHLTSAYEYLELRF---NKTV 141 Query: 125 RILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAY 184 R+ G+ T F Y+G LN + G D L +L +V YT +GGLK+V + Sbjct: 142 RVCGTVTFIFQMVIYMGVVLYAPSLALNAVTGFDLWLSVLALGIVCTVYTALGGLKAVIW 201 Query: 185 TDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAAIV 244 TD Q +VM L + IVG + ++A + ++ I G V Sbjct: 202 TDVFQTLVMFLGQLAVIIVGSAKVGGLGRVWAVA---------SQHGRISGFELDPDPFV 252 Query: 245 ---FVIAEFSWFFGYLG--GMPQLSI-RFMAIKDDKNAKLARNIGIGWTIIAYIGALMIG 298 F F F L G+ Q + R+++ + +K A L+ + ++ +IG Sbjct: 253 RHTFWTLAFGGVFMMLSLYGVNQAQVQRYLSSRTEKAAVLSCYAVFPFQQVSLCVGCLIG 312 Query: 299 WIGIAIFG--PNGLKD----PEQVMPSVMLKLFP--PALAAVFITGAVAAMLSTADSLLI 350 + A + P ++ P+Q + ++ L P L +FI + LST S Sbjct: 313 LVMFAYYQEYPMSIQQAQAAPDQFVLYFVMDLLKGLPGLPGLFIACLFSGSLSTISSAFN 372 Query: 351 LSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTW 410 +T E++++P+ E +++M+SR G++ L MAY I + +G Sbjct: 373 SLATVTMEDLIRPWF--PEFSEARAIMLSRGLAFGYGLLCLGMAY------ISSQMGPVL 424 Query: 411 AGIGDTFSVI--VILTLF-WKRFHGKAVPPTIIAGL---LFTVFWISSG 453 F ++ +L LF F A PP + GL L FWI G Sbjct: 425 QAAISIFGMVGGPLLGLFCLGMFFPCANPPGAVVGLLAGLVMAFWIGIG 473 >gi|11429441 solute carrier family 5 (sodium-dependent vitamin transporter), member 6 [Homo sapiens] Length = 635 Score = 86.6 bits (211), Expect = 6e-16 Identities = 115/469 (24%), Positives = 196/469 (41%), Gaps = 51/469 (10%) Query: 10 VLVFYLGFLISVGIY---QGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPG 66 V V L +++G+Y +G + + +A R++ ALS AT +SA +LG+P Sbjct: 31 VFVLLLVLSLAIGLYHACRGWGRHTVGELLMADRKMGCLPVALSLLATFQSAVAILGVPS 90 Query: 67 FAFAAGLAAIWPAIGCV--LGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWI 124 + G W +GC LG+++ +F + + +Y+ R K + Sbjct: 91 EIYRFG-TQYW-FLGCCYFLGLLIPAHIFIPVFYR----LHLTSAYEYLELRF---NKTV 141 Query: 125 RILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAY 184 R+ G+ T F Y+G LN + G D L +L +V YT +GGLK+V + Sbjct: 142 RVCGTVTFIFQMVIYMGVVLYAPSLALNAVTGFDLWLSVLALGIVCTVYTALGGLKAVIW 201 Query: 185 TDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAAIV 244 TD Q +VM L + IVG + ++A + ++ I G V Sbjct: 202 TDVFQTLVMFLGQLAVIIVGSAKVGGLGRVWAVA---------SQHGRISGFELDPDPFV 252 Query: 245 ---FVIAEFSWFFGYLG--GMPQLSI-RFMAIKDDKNAKLARNIGIGWTIIAYIGALMIG 298 F F F L G+ Q + R+++ + +K A L+ + ++ +IG Sbjct: 253 RHTFWTLAFGGVFMMLSLYGVNQAQVQRYLSSRTEKAAVLSCYAVFPFQQVSLCVGCLIG 312 Query: 299 WIGIAIFG--PNGLKD----PEQVMPSVMLKLFP--PALAAVFITGAVAAMLSTADSLLI 350 + A + P ++ P+Q + ++ L P L +FI + LST S Sbjct: 313 LVMFAYYQEYPMSIQQAQAAPDQFVLYFVMDLLKGLPGLPGLFIACLFSGSLSTISSAFN 372 Query: 351 LSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTW 410 +T E++++P+ E +++M+SR G++ L MAY I + +G Sbjct: 373 SLATVTMEDLIRPWF--PEFSEARAIMLSRGLAFGYGLLCLGMAY------ISSQMGPVL 424 Query: 411 AGIGDTFSVI--VILTLF-WKRFHGKAVPPTIIAGL---LFTVFWISSG 453 F ++ +L LF F A PP + GL L FWI G Sbjct: 425 QAAISIFGMVGGPLLGLFCLGMFFPCANPPGAVVGLLAGLVMAFWIGIG 473 >gb|AAC12270.1| (AF026554) sodium-dependent multi-vitamin transporter [Rattus norvegicus] >gi|3746793|gb|AAC64060.1| (AF081204) sodium dependent multivitamin transporter [Rattus norvegicus] >gi|3746795|gb|AAC64061.1| (AF081205) sodium dependent multivitamin transporter [Rattus norvegicus] Length = 634 Score = 86.2 bits (210), Expect = 8e-16 Identities = 109/471 (23%), Positives = 195/471 (41%), Gaps = 47/471 (9%) Query: 7 ILAVLVFYLGFLIS--VGIY---QGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCL 61 ++ +VF L ++S +G+Y +G + + +A R++ ALS AT +SA + Sbjct: 25 VVDYVVFGLLLVLSLVIGLYHACRGWGRHTVGELLMADRKMGCLPVALSLLATFQSAVAI 84 Query: 62 LGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAE 121 LG P + G + LG+++ +F + + +Y+ R +A Sbjct: 85 LGGPAEIYRFGTQYWFLGCSYFLGLLIPAHIFIPVFYR----LHLTSAYEYLELRFNKA- 139 Query: 122 KWIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKS 181 +RI G+ T F Y+G LN + G D L +L +V YT +GGLK+ Sbjct: 140 --VRICGTVTFIFQMVVYMGVALYAPSLALNAVTGFDLWLSVLALGIVCNIYTALGGLKA 197 Query: 182 VAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAA 241 V +TD Q ++M L +V IVG + ++A + L +G++ Sbjct: 198 VIWTDVFQTLIMFLGQLVVIIVGAAKVGGLGHVWAVASQHGLI-SGIELD---------- 246 Query: 242 AIVFVIAEFSWFFGYLGGMPQLSI---------RFMAIKDDKNAKLARNIGIGWTIIAYI 292 FV F W + G LS+ R+++ +K A L+ +A Sbjct: 247 PDPFVRHTF-WTLAFGGVFMMLSLYGVNQAQVQRYLSSHSEKAAVLSCYAVFPCQQVALC 305 Query: 293 GALMIGWIGIAIFGPNGLK-DPEQVMPSVMLKLF-------PPALAAVFITGAVAAMLST 344 + +IG + A + + EQ P ++ F P L +F+ + LST Sbjct: 306 MSCLIGLVMFAYYKKYSMSPQQEQAAPDQLVLYFVMDLLKDMPGLPGLFVACLFSGSLST 365 Query: 345 ADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHL--I 402 S +T E++++P+ + +++M+SR + G++ L MAY V SHL + Sbjct: 366 ISSAFNSLATVTMEDLIQPWF--PQLTETRAIMLSRSLAFAYGLVCLGMAY-VSSHLGSV 422 Query: 403 YTIVGYTWAGIGDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSG 453 + +G + L +F+ + ++ GL FWI G Sbjct: 423 LQAALSIFGMVGGPLLGLFCLGMFFPCANPLGAIVGLLTGLTM-AFWIGIG 472 >pir||S68513 thyroid iodide transport protein - rat >gi|1399954|gb|AAB03338.1| (U60282) thyroid sodium/iodide symporter NIS [Rattus norvegicus] Length = 618 Score = 85.8 bits (209), Expect = 1e-15 Identities = 96/404 (23%), Positives = 164/404 (39%), Gaps = 43/404 (10%) Query: 10 VLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGFAF 69 +L+ G + VG+ +G + +S DF GRQL LS A+ SA +LG+P A Sbjct: 23 MLLVSTGIGLWVGLARGGQ-RSADDFFTGGRQLAAVPVGLSLAASFMSAVQVLGVPAEAA 81 Query: 70 AAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRILGS 129 GL +W G +L ++ +F + + Y+ R A +R+ G+ Sbjct: 82 RYGLKFLWMCAGQLLNSLLTAFLFLPIFYR----LGLTSTYQYLELRFSRA---VRLCGT 134 Query: 130 ATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTDTVQ 189 Y G +LN + GLD +L T ++ YT +GG+K+V +TD Q Sbjct: 135 LQYLVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTLYTTVGGMKAVVWTDVFQ 194 Query: 190 AIVMILTLIVAPIVGVIYIA----------NHPELYATSVTAALSKAGVKYSTILGGMAG 239 +VM++ V GVI + NH + ++ I+GG Sbjct: 195 VVVMLVGFWVILARGVILLGGPRNVLSLAQNHSRINLMDFDPDPRSRYTFWTFIVGG--- 251 Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSI-RFMAIKDDKNAKLARNIGIGWTIIAYIGALMIG 298 W Y G+ Q + R++A + AKLA + + A G Sbjct: 252 ---------TLVWLSMY--GVNQAQVQRYVACHTEGKAKLALLVNQLGLFLIVASAACCG 300 Query: 299 WIGIAIFG------PNGLKDPEQVMPSVMLKLFP--PALAAVFITGAVAAMLSTADSLLI 350 + + + P+Q MP ++L +F P + +F+ A + LSTA + + Sbjct: 301 IVMFVYYKDCDPLLTGRISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSIN 360 Query: 351 LSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMA 394 + E+++KP + PRK + +S+ + G L +A Sbjct: 361 AMAAVTVEDLIKPRM--PGLAPRKLVFISKGLSFIYGSACLTVA 402 >gb|AAD37480.1|AF080067_1 (AF080067) sodium-dependent multi-vitamin transporter [Oryctolagus cuniculus] Length = 636 Score = 84.7 bits (206), Expect = 2e-15 Identities = 115/472 (24%), Positives = 189/472 (39%), Gaps = 57/472 (12%) Query: 10 VLVFYLGFLISVGIY---QGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPG 66 V L F +++G+Y +G + +A R++ ALS AT +SA +LG+P Sbjct: 31 VFSLLLVFSLAIGLYHACRGWGKHTVGQLLLADRRMGCLPVALSLLATFQSAVAILGVPS 90 Query: 67 FAFAAGLAAIWPAIGCV--LGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWI 124 + G W +GC LG+++ VF + + +Y+ R K + Sbjct: 91 EIYRFG-TQYW-FLGCCYFLGLLIPAHVFIPVFYR----LHLTSAYEYLELRF---NKVV 141 Query: 125 RILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAY 184 RI G+ T F Y+G LN + G D L +L +V YT +GGLK+V + Sbjct: 142 RICGTVTFIFQMVIYMGVVLYAPSLALNAVTGFDLWLSVLTLGIVCTIYTALGGLKAVIW 201 Query: 185 TDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAAIV 244 TD Q +VM L + IVG + ++ + L +G++ Sbjct: 202 TDVFQTLVMFLGQLAVIIVGSAKVGGLGRVWDVASQHGLI-SGIELD----------PDP 250 Query: 245 FVIAEFSWFFGYLGGMPQLSI---------RFMAIKDDKNAKLARNIGIGWTIIAYIGAL 295 FV F W + G LS+ R+++ + +K A L+ +A Sbjct: 251 FVRHTF-WTLAFGGVFMMLSLYGVNQAQVQRYLSSRTEKAAVLSCYAVFPCQQVALSMGC 309 Query: 296 MIGWIGIAIFGPNGLKDPEQVMPSVMLKLF--------PPALAAVFITGAVAAMLSTADS 347 +IG + A + + + S L+ P L +F+ + LST S Sbjct: 310 LIGLVMFAYYQEYPMSTQQSQAASDQFVLYFVMDLLKGLPGLPGLFVACLFSGSLSTISS 369 Query: 348 LLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVG 407 +T E++++P+ E +++M+SR G++ L MAY I + +G Sbjct: 370 AFNSLATVTMEDLIRPWF--PECSEAQAIMLSRSLAFGYGLLCLGMAY------ISSQMG 421 Query: 408 YTWAGIGDTFSVI--VILTLF-WKRFHGKAVPPTIIAGL---LFTVFWISSG 453 F ++ +L LF F A PP I GL L FWI G Sbjct: 422 PVLQAAISIFGMVGGPLLGLFCLGMFFPCANPPGAIVGLLAGLIMAFWIGIG 473 >pir||T35201 probable transmembrane transport - Streptomyces coelicolor >gi|3036892|emb|CAA18525.1| (AL022374) SC5B8.17, probable transmembrane transport protein, len: 530 aa; member of the sodium:solute symporter family, similar to many e.g. YJCG_ECOLI P32705 hypothetical protein , (549 aa), fasta scores; opt: 935 z-score: 1534.8 E(): 0, 43.6% ident> Length = 530 Score = 83.9 bits (204), Expect = 4e-15 Identities = 96/464 (20%), Positives = 197/464 (41%), Gaps = 33/464 (7%) Query: 6 QILAVLVFYLGFLISVGI--YQGRKAK-SHKDFSIAGRQLPGWVAALSERATGESAWCLL 62 Q LA+L+F +++GI + GR+ + S ++F GR + SA L Sbjct: 6 QTLALLLFSTFVAVTLGITTWVGRRRQGSAEEFYAGGRLFSPMENGFAISGDYMSAASFL 65 Query: 63 GLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEK 122 G+ G G + ++G +VAW V + + T D +A R E+ Sbjct: 66 GISGLIALNGYDGMLYSVG----FLVAWLVVLFLVAELVRNCGRFTLADVVAARM--RER 119 Query: 123 WIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITAL----VILPYTVMGG 178 +RI + Y+ AQ +G G ++ L G + T + +++ Y +GG Sbjct: 120 PVRIAAGTSSVTVSVLYLVAQMVGAGSLVALLLGGTSEAARTWTVIGVGALMVIYVSLGG 179 Query: 179 LKSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMA 238 +++ + V+A++++ + + ++ + H ++ TAA ++G + + G+A Sbjct: 180 MRATTWIQIVKAVLLLGGTVA--LTALVLVRFHGDVDRLLRTAA-ERSGHGEAFLAPGLA 236 Query: 239 ----GAAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGA 294 A F+ + G G+P + RF + + A+ + IG Y+ Sbjct: 237 YGGDWVARFDFISLGLALVLG-TAGLPHILSRFYTVPTARAARRSVVWSIGLIGGFYLMT 295 Query: 295 LMIGWIGIAIFGPNGLKDPEQV----MPSVMLKLFPPA-------LAAVFITGAVAAMLS 343 +++G+ A+ GPN ++ +P + L L A L AV A A +L+ Sbjct: 296 IVLGFGAAALVGPNAVRASNAAGNTAVPLLALDLGGGAHSTGGTVLFAVVAAVAFATILA 355 Query: 344 TADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIY 403 + + SS + ++ + + + PR + V+R+ V +G +A+ + + + Sbjct: 356 VVAGITLASSASVAHDLYAS-LRRRHSKPRSEVAVARVAAVGIGAVAIGLGLLARDLNVA 414 Query: 404 TIVGYTWAGIGDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTV 447 +VG +A +++ +LFW+ F + + GL+ +V Sbjct: 415 FLVGLAFAVAASANLPVLLYSLFWRGFTTRGAVWAVYGGLVPSV 458 >pir||D72694 hypothetical protein APE0972 - Aeropyrum pernix (strain K1) >gi|5104641|dbj|BAA79956.1| (AP000060) 460aa long hypothetical protein [Aeropyrum pernix] Length = 460 Score = 83.5 bits (203), Expect = 5e-15 Identities = 85/349 (24%), Positives = 167/349 (47%), Gaps = 38/349 (10%) Query: 29 AKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGFAFAAGLAAIWPAIGCVLGIIV 88 A+ +F +AGR+L G+++A++ AT S++ ++GL G A+ G+ ++ + ++ ++ Sbjct: 2 ARGEGEFYLAGRRLTGFLSAMTYAATTYSSFMIVGLVGLAYFTGIGSLVFELAYLVATVI 61 Query: 89 AWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRILGSATIAFFFFFYVGAQYLGGG 148 ++F+ R+ + + + V+ + +A W+ + S Y AQ G Sbjct: 62 LLSLFSRRVWRMSRERGWVSPGEMLADL--LGSPWVALTASLVFLVSLVPYASAQLKGIA 119 Query: 149 KVLNTLFGLDP------KLGMLITALVILPYTVMGGLKSVAYTDTVQAIVMILTLIVAPI 202 + + + G P + + + L++L ++++ G++ V TD Q L ++ A Sbjct: 120 ETIVAIAGYSPGDNTAYMVAVGVALLILLAWSLLAGVRGVVLTDAFQG----LWMLTAGS 175 Query: 203 VGVIYIANH--PELYATSVTAALSKAGVKYSTILGGMAGAAAIVFVIAEFSWFFGYLGGM 260 + +++A+ + A+ V +A+ AG L M A ++ + W F + Sbjct: 176 LLFLWLASRVFSKSGASEVLSAMESAG------LFDMWSATLLIGFVT--PWVF-FAVTN 226 Query: 261 PQLSIRFMAIKDDKNAKLARNI------GIGWTI-IAYIGALMIGWI--GIAIFGPNGLK 311 PQ+ R KD+++ L R I G+ +T+ + IG L + GI P G Sbjct: 227 PQVVQRLYMPKDEES--LRRMILYFFLFGLYYTVLVVAIGFLARAGVELGILSIEPQG-- 282 Query: 312 DPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSENI 360 +QV P +L L P LAA+ T VAA +STADS+++ ++ S +I Sbjct: 283 -RDQVTPQ-LLSLAHPLLAALVFTSIVAASVSTADSIILALASSASRDI 329 >dbj|BAB05941.1| (AP001514) Na+/myo-inositol cotransporter [Bacillus halodurans] Length = 580 Score = 81.9 bits (199), Expect = 1e-14 Identities = 109/498 (21%), Positives = 209/498 (41%), Gaps = 36/498 (7%) Query: 7 ILAVLVFYLGFLISVGIYQ--GRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGL 64 ILA + Y F++ Y+ G S + + GR L G V A S T S ++GL Sbjct: 5 ILASFLMYSIFVMWFSWYKTRGTDLSSSDGYFLGGRSLTGIVIASSLILTNLSTEQVVGL 64 Query: 65 PGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWI 124 G AF + + + + +I+ VF R K T D++ +R + I Sbjct: 65 NGQAFGESMVVMAWEVTAPIALILMAFVFLPRYLK----LGITTIPDFLEQRFDLRTRQI 120 Query: 125 R----ILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVI----LPYTVM 176 +LG AT+ Y GA + L+++ + P + +L ++ I Y ++ Sbjct: 121 VSVLFLLGYATVFLPTVLYSGALVIDSIFSLSSVMDISPFMIVLCISIAIGIISCGYVIL 180 Query: 177 GGLKSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGG 236 GGLK+ A +DT+ I +I+ ++ PI+ + + +A+ V +S K + I Sbjct: 181 GGLKACAMSDTINGIGLIIGGLLIPILALFVLGRGD--FASGVGELVSANPTKLNAIGND 238 Query: 237 MAGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIGWTIIAYIGALM 296 A V + Y + R +A K+ + + I ++ Sbjct: 239 QASVPWAVLLTGLLFNNLFYWCTNQSIIQRTLAAKNLAEGQKGVLFAGMFKIFGAAFLVL 298 Query: 297 IGWIGIAIFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEF 356 G I ++G + L + + PS+++ + P AL+ A+LS+ +++L S T F Sbjct: 299 PGIIAYLLYG-DVLANADMAYPSLVIDVMPVALSGFLAAVLFGAILSSFNNVLNSSITLF 357 Query: 357 SENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVV---PSHLIYTIVGYTWAGI 413 + +I KP I+K A + + R+ L I A+++A + P L Y + G Sbjct: 358 TLDIYKP-IFKPNAKEPELVKAGRIFAACLAITAVVIAPFILYAPQGLYYFL--QEMNGF 414 Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTVFWISSGLDAKVSVRLMNFIVTF---- 469 + +++ F+ ++ + P ++A + V + S KV + +NF+ Sbjct: 415 YSLPIIAMVIVGFFSKYVPASAPKVLVA--VHVVLYAGS----KVVLGEVNFLYVLSVLF 468 Query: 470 ---IVAIIATYAIKPEKT 484 ++ ++ +KP +T Sbjct: 469 PINVLVMLIVGRLKPRET 486 >sp|P23723|PUTP_KLEPN SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE) >gi|443996|emb|CAA52889.1| (X74934) proline permease [Klebsiella pneumoniae] Length = 160 Score = 80.8 bits (196), Expect = 3e-14 Identities = 43/117 (36%), Positives = 62/117 (52%), Gaps = 1/117 (0%) Query: 1 MEARTQILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWC 60 M T +L + Y+ ++ +G R K+ D+ + GR L +V ALS A+ S W Sbjct: 1 MAISTPMLVTFIVYIFGMVLIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWL 60 Query: 61 LLGLPGFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAE-KYDAVTFVDYIAKR 116 L+GLPG F +G++ W AIG LG + W + AGRLR E +A+T DY R Sbjct: 61 LMGLPGAIFISGISESWIAIGLTLGAWINWKLVAGRLRVHTEVNNNALTXPDYFTGR 117 >emb|CAC16517.1| (AL450223) putative integral membrane transport protein [Streptomyces coelicolor] Length = 523 Score = 80.0 bits (194), Expect = 6e-14 Identities = 88/429 (20%), Positives = 184/429 (42%), Gaps = 30/429 (6%) Query: 8 LAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGF 67 L V+V YL + +G+ + + KS KD+ + +P W + S AT S ++ +PG Sbjct: 6 LVVIVVYLIGIAWIGLRKAGRQKSAKDYFVGEGHMPWWTVSFSVVATETSVLTVISVPGG 65 Query: 68 AFAA-GLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRI 126 A++ G + A+G V+G +V V ++ V+ Y+ R +++ Sbjct: 66 AYSGQGFGNVELALGYVVGRVVVATVLIPLYKRGG----FVSAYQYLGDRF-----GLKL 116 Query: 127 LGSATIAFFF--FFYVGAQYLGGG---KVLNTLFGLDP--KLGMLITALVILPYTVMGGL 179 G A++ F F G + K+L FG+ + +++ L+ + YT +GG+ Sbjct: 117 QGLASVTFVFTRLLAEGVRLFASAIPIKLLLDEFGVHASYRAIIIVITLITVVYTYLGGI 176 Query: 180 KSVAYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAG 239 K+V +TD +Q ++ + ++A V ++ + YA ++ A + + + Sbjct: 177 KAVIWTDAIQMVLYLGGAVLAVAVLSAHVGG--DGYARALDAGKFQLFDTDFNLAHILTS 234 Query: 240 AAAIVFVIAEFSWFFGYLGGMPQLSIRFM----AIKDDKNAKLARNIGIGWTIIAY--IG 293 A+ I + F G QL ++ + +++ + A +A + + A+ +G Sbjct: 235 PFALPTAIIGGAIFAMASHGSDQLIVQRVLATRTLREGQKAMIASGVFVTVQFAAFSLVG 294 Query: 294 ALMIGWIGIAIFGPNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353 AL+ + F GL + + P +L P ++ + + G + A + + S L S Sbjct: 295 ALLWSYNEGRSFAELGLSSSDNLYPEFILHGLPVVVSGLLVAGILGAAMGSLSSALNSMS 354 Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALI-MAYVVPSHLIY----TIVGY 408 +I+ + ++ + +T V ++A+ A+ + +Y TI GY Sbjct: 355 NSTVADIIHSFFRSTPSEEALLRLARWMTLVWATLMAVFACAFSASTGNVYLTGLTIAGY 414 Query: 409 TWAGIGDTF 417 T+ + F Sbjct: 415 TYGALLGAF 423 >pir||S52839 dhlC protein - Xanthobacter autotrophicus >gi|763398|emb|CAA60038.1| (X86084) dhlC [Xanthobacter autotrophicus] Length = 516 Score = 78.8 bits (191), Expect = 1e-13 Identities = 97/454 (21%), Positives = 185/454 (40%), Gaps = 29/454 (6%) Query: 8 LAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPGF 67 LA+ V L +++ + R+ ++ DF A L + SA LG G Sbjct: 6 LAIFVAILALTLAITWWAARRTRTASDFYTADGTLGPIQNGFALAGDWMSAAAFLGFSGL 65 Query: 68 AFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKR--HPEAEKWIR 125 A G+ A G ++ + + A +R T D IA R P+A + Sbjct: 66 AALYGMDGSLYAAGALVAFLAILMLVAEPIRNTGR----FTLGDVIAFRMQRPQA-RLAA 120 Query: 126 ILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYT 185 +LG+ ++ Y+ Q GG ++ L G+ + +++ L +L Y V GG+ + + Sbjct: 121 VLGTVVVSLA---YLVPQMAGGAALIKLLLGVPYAISIVVVGLGMLVYVVFGGMIATTWV 177 Query: 186 DTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKA-GVKYSTILGGMAGAAAIV 244 ++A++ L+ A V V + H SV AA G K + G + Sbjct: 178 QIIKAVM----LLSAAAVLVALLLAHFGFDPFSVFAAAEDTYGAK--ILAPGNYLKHPLD 231 Query: 245 FVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAK--------LARNIGIGWTIIAYIGALM 296 + S+ FG G+P + RF + D + A+ LA + + T+I A++ Sbjct: 232 QLSLGLSFAFG-TAGLPHVMTRFYTVPDAQTARRSAVWLMFLAGSFFLVTTLIGLGSAVL 290 Query: 297 IGWIGIAIFGPNG---LKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSS 353 +G I G L Q + + AV + A A +L+ +L + +S Sbjct: 291 VGQDAIRAADKGGNLALPLLAQHLGGGPDSIGGQVFLAVVVAVAFATILAVVAALTLSTS 350 Query: 354 TEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGI 413 + ++ + ++ + V+R++TV + A++ + + +V + Sbjct: 351 GAIAHDLYVNVLRGGHVSEQEQVKVARISTVIVSAFAILFGLLAQGINVAVLVILAISVA 410 Query: 414 GDTFSVIVILTLFWKRFHGKAVPPTIIAGLLFTV 447 +++L+LFW+RF+ V ++AGL+ V Sbjct: 411 ASANFPVIVLSLFWQRFNTAGVVTGMVAGLVSAV 444 >gb|AAF17249.1|AF208031_1 (AF208031) SGLT1 protein [Mus musculus] Length = 665 Score = 76.9 bits (186), Expect = 5e-13 Identities = 102/485 (21%), Positives = 202/485 (41%), Gaps = 61/485 (12%) Query: 8 LAVLVFYLGFLISVGIYQ--GRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLP 65 ++V+V Y +++VG++ + F +AGR + W S A+ + +GL Sbjct: 29 ISVIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGLA 88 Query: 66 GFAFAAGLAA---IWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEK 122 G AAG+A W A+ VL +++ W + K VT +Y+ KR K Sbjct: 89 GTGAAAGIAMGGFEWNAL--VLVVVLGWIFVPIYI-----KAGVVTMPEYLRKRF--GGK 139 Query: 123 WIRI-LGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKS 181 I+I L ++ + F + A G +N GLD L + I + YT+ GGL + Sbjct: 140 RIQIYLSVLSLLLYIFTKISADIFSGAIFINLALGLDIYLAIFILLAITALYTITGGLAA 199 Query: 182 VAYTDTVQAIVMILTLIVAPIVGVIYIANHP---ELYATSVTAALSKAGVKYSTILGGMA 238 V YTDT+Q +M++ + + + + Y ++ +S Sbjct: 200 VIYTDTLQTAIMLVGSFILTGFAFNEVGGYEAFMDKYMKAIPTKVSNGNFTAKEECYTPR 259 Query: 239 GAAAIVF---VIAEFSWFFGYLGGMPQLSIRF-----MAIKDDKNAKLARNIGIGWTIIA 290 + +F + + W G + G+ L++ + + ++ +AK ++ G T+ Sbjct: 260 ADSFHIFRDPITGDMPW-PGLIFGLAILALWYWCTDQVIVQRCLSAKNMSHVKAGCTLCG 318 Query: 291 YIGAL------MIGWIGIAIFGPN-GLKDPEQ--------------VMPSVMLKLFPPAL 329 Y+ L M G I ++ PE+ P+++++L P L Sbjct: 319 YLKLLPMFLMVMPGMISRILYTEKIACVLPEECQKYCGTPVGCTNIAYPTLVVELMPNGL 378 Query: 330 AAVFITGAVAAMLSTADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGII 389 + ++ +A+++S+ S+ +ST F+ +I + +A ++ ++ RL + L I Sbjct: 379 RGLMLSVMMASLMSSLTSIFNSASTLFTMDIYTK--IRKKASEKELMIAGRLFILVLIGI 436 Query: 390 ALIMAYVVPS-------HLIYTIVGYTWAGIGDTFSVIVILTLFWKRFHGKAVPPTIIAG 442 ++ +V S I +I Y +G + + +L +F KR + + +I G Sbjct: 437 SIAWVPIVQSAQSGQLFDYIQSITSY----LGPPIAAVFLLAIFCKRVNEQGAFWGLILG 492 Query: 443 LLFTV 447 L + Sbjct: 493 FLIGI 497 >pir||S48857 glucose transport protein - sheep >gi|2148056|pir||S59638 glucose transport protein SGLT1, parotid gland - sheep Length = 664 Score = 76.9 bits (186), Expect = 5e-13 Identities = 109/528 (20%), Positives = 210/528 (39%), Gaps = 68/528 (12%) Query: 8 LAVLVFYLGFLISVGIYQ--GRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLP 65 ++V+V Y +++VG++ + F +AGR + W S A+ + +GL Sbjct: 29 ISVIVIYFVVVMAVGLWHMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGLA 88 Query: 66 GFAFAAGLAA---IWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEK 122 G AAG+A W A+ +L +++ W + K VT +Y+ KR Sbjct: 89 GTGAAAGIATGGFEWNAL--ILVVLLGWVFVPIYI-----KAGVVTMPEYLRKRFGGQRI 141 Query: 123 WIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSV 182 + L ++ + F + A G +N GLD L + I + YT+ GGL +V Sbjct: 142 QV-YLSVLSLVLYIFTKISADIFSGAIFINLALGLDLYLAIFILLAITALYTITGGLAAV 200 Query: 183 AYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAA 242 YTDT+Q ++M+L + + + + A + +T+ A Sbjct: 201 IYTDTLQTVIMLLGSFILTGFAFHEVGGYSAFVTKYMNAIPTVTSYGNTTVKKECYTPRA 260 Query: 243 IVFVI------AEFSWFFGYLGGMPQLSIRF-----MAIKDDKNAKLARNIGIGWTIIAY 291 F I + W G + G+ +S+ + + ++ +AK ++ G + Y Sbjct: 261 DSFHIFRDPLKGDLPW-PGLIFGLTIISLWYWCTDQVIVQRCLSAKNMSHVKAGCIMCGY 319 Query: 292 IGAL------MIGWIGIAIFGPN-GLKDPEQ--------------VMPSVMLKLFPPALA 330 + L M G I +F P + P+++++L P L Sbjct: 320 MKLLPMFLMVMPGMISRILFTEKVACTVPSECEKYCGTKVGCTNIAYPTLVVELMPNGLR 379 Query: 331 AVFITGAVAAMLSTADSLLILSSTEFSENILKPYIYKNEADPRKSLMVS----RLTTVSL 386 + ++ +A+++S+ S+ +ST F+ +I Y + K LM++ L + + Sbjct: 380 GLMLSVMLASLMSSLTSIFNSASTLFTMDI---YTKIRKKASEKELMIAGRLFMLVLIGV 436 Query: 387 GIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVIVILTLFWKR------FHGKAVPPTII 440 I + + S ++ + + +G + + +L +F KR F G + I Sbjct: 437 SIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFCKRVNEPGAFWGLIIGFLIG 496 Query: 441 AGLLFTVFWISSGLDAKVS--------VRLMNF-IVTFIVAIIATYAI 479 + T F +G + S V + F I+ F++ II AI Sbjct: 497 VSRMITEFAYGTGSCMEPSNCPTIICGVHYLYFAIILFVITIIVILAI 544 >sp|P53791|SL51_SHEEP SODIUM/GLUCOSE COTRANSPORTER 1 (NA(+)/GLUCOSE COTRANSPORTER 1) (HIGH AFFINITY SODIUM-GLUCOSE COTRANSPORTER) >gi|2119800|pir||S59637 glucose transport protein SGLT1, intestinal - sheep >gi|861071|emb|CAA57808.1| (X82410) sodium/glucose cotransporter [Ovis aries] >gi|861073|emb|CAA57809.1| (X82411) sodium/glucose cotransporter-like protein [Ovis aries] >gi|2326776|emb|CAA04483.1| (AJ001026) sodium/glucose symporter-like protein [Ovis aries] Length = 664 Score = 76.5 bits (185), Expect = 6e-13 Identities = 109/528 (20%), Positives = 210/528 (39%), Gaps = 68/528 (12%) Query: 8 LAVLVFYLGFLISVGIYQ--GRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLP 65 ++V+V Y +++VG++ + F +AGR + W S A+ + +GL Sbjct: 29 ISVIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGLA 88 Query: 66 GFAFAAGLAA---IWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEK 122 G AAG+A W A+ +L +++ W + K VT +Y+ KR Sbjct: 89 GTGAAAGIATGGFEWNAL--ILVVLLGWVFVPIYI-----KAGVVTMPEYLRKRFGGQRI 141 Query: 123 WIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSV 182 + L ++ + F + A G +N GLD L + I + YT+ GGL +V Sbjct: 142 QV-YLSVLSLVLYIFTKISADIFSGAIFINLALGLDLYLAIFILLAITALYTITGGLAAV 200 Query: 183 AYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAA 242 YTDT+Q ++M+L + + + + A + +T+ A Sbjct: 201 IYTDTLQTVIMLLGSFILTGFAFHEVGGYSAFVTKYMNAIPTVTSYGNTTVKKECYTPRA 260 Query: 243 IVFVI------AEFSWFFGYLGGMPQLSIRF-----MAIKDDKNAKLARNIGIGWTIIAY 291 F I + W G + G+ +S+ + + ++ +AK ++ G + Y Sbjct: 261 DSFHIFRDPLKGDLPW-PGLIFGLTIISLWYWCTDQVIVQRCLSAKNMSHVKAGCIMCGY 319 Query: 292 IGAL------MIGWIGIAIFGPN-GLKDPEQ--------------VMPSVMLKLFPPALA 330 + L M G I +F P + P+++++L P L Sbjct: 320 MKLLPMFLMVMPGMISRILFTEKVACTVPSECEKYCGTKVGCTNIAYPTLVVELMPNGLR 379 Query: 331 AVFITGAVAAMLSTADSLLILSSTEFSENILKPYIYKNEADPRKSLMVS----RLTTVSL 386 + ++ +A+++S+ S+ +ST F+ +I Y + K LM++ L + + Sbjct: 380 GLMLSVMLASLMSSLTSIFNSASTLFTMDI---YTKIRKKASEKELMIAGRLFMLVLIGV 436 Query: 387 GIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVIVILTLFWKR------FHGKAVPPTII 440 I + + S ++ + + +G + + +L +F KR F G + I Sbjct: 437 SIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFCKRVNEPGAFWGLIIGFLIG 496 Query: 441 AGLLFTVFWISSGLDAKVS--------VRLMNF-IVTFIVAIIATYAI 479 + T F +G + S V + F I+ F++ II AI Sbjct: 497 VSRMITEFAYGTGSCMEPSNCPTIICGVHYLYFAIILFVITIIVILAI 544 >sp|P31448|YIDK_ECOLI HYPOTHETICAL 62.1 KD PROTEIN IN EMRD-GLVG INTERGENIC REGION >gi|7430324|pir||H65169 probable transport protein yidK - Escherichia coli (strain K-12) >gi|290528|gb|AAA62031.1| (L10328) similar to glucose transport proteins [Escherichia coli] >gi|1790113|gb|AAC76702.1| (AE000445) putative cotransporter [Escherichia coli K12] Length = 571 Score = 76.1 bits (184), Expect = 8e-13 Identities = 114/510 (22%), Positives = 214/510 (41%), Gaps = 65/510 (12%) Query: 11 LVFYLGFLISVGIYQGRKAK-----SHKDFSIAGRQLPGWVAALSERATGESAWCLLGLP 65 ++ ++GF + V + K + S + + +AGR L V A S T S L+GL Sbjct: 6 ILSFVGFTLLVAVITWWKVRKTDTGSQQGYFLAGRSLKAPVIAASLMLTNLSTEQLVGLS 65 Query: 66 GFAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIR 125 G A+ +G++ + + + +I +F R K T D++ +R+ +K R Sbjct: 66 GQAYKSGMSVMGWEVTSAVTLIFLALIFLPRYLKRG----IATIPDFLEERY---DKTTR 118 Query: 126 ILGSATIAFFFFFYVGAQYL-----GGGKVLNTLFGLDPKL----GMLITALVILP---- 172 I+ I F F G +L G LN+LF + L G I LVIL Sbjct: 119 II----IDFCFLIATGVCFLPIVLYSGALALNSLFHVGESLQISHGAAIWLLVILLGLAG 174 Query: 173 --YTVMGGLKSVAYTDTVQAIVMILTLIVAPIVGVIYIANHP-----ELYATSVTAALSK 225 Y V+GGL+++A D++ I +++ ++ P+ G+I + E T L+ Sbjct: 175 ILYAVIGGLRAMAVADSINGIGLVIGGLMVPVFGLIAMGKGSFMQGIEQLTTVHAEKLNS 234 Query: 226 AGVKYSTILGGMAGAAAIVFVIAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIG 285 G + G A I ++ F W G+ Q ++ ++ + + L Sbjct: 235 IGGPTDPLPIGAAFTGLI--LVNTFYWCTNQ--GIVQRTLASKSLAEGQKGALLT----- 285 Query: 286 WTIIAYIGALMIGWIGIAIFG-PNGLKDPEQVMPSVMLKLFPPALAAVFITGAVAAMLST 344 ++ + L++ G+ F L + P+++ + P + F A++ST Sbjct: 286 -AVLKMLDPLVLVLPGLIAFHLYQDLPKADMAYPTLVNNVLPVPMVGFFGAVLFGAVIST 344 Query: 345 ADSLLILSSTEFSENILKPYIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVV---PSHL 401 + L +ST FS I + I +N A+P++ + V R + I+++++A + P L Sbjct: 345 FNGFLNSASTLFSMGIYRRIINQN-AEPQQLVTVGRKFGFFIAIVSVLVAPWIANAPQGL 403 Query: 402 IYTIVGYTWA----GIGDT-FSVIVILTLFWKRFHGKAVPPTIIAGLL--FTVFWISSGL 454 Y+W GI + I+I+ F+ R A + G++ T+ ++ Sbjct: 404 ------YSWMKQLNGIYNVPLVTIIIMGFFFPRIPALAAKVAMGIGIISYITINYLVKFD 457 Query: 455 DAKVSVRLMNFIVTFIVAIIATYAIKPEKT 484 + V F + +V ++ + IKP T Sbjct: 458 FHFLYVLACTFCINVVVMLVIGF-IKPRAT 486 >pir||S48858 glucose transport protein homolog - sheep Length = 664 Score = 75.7 bits (183), Expect = 1e-12 Identities = 109/528 (20%), Positives = 209/528 (38%), Gaps = 68/528 (12%) Query: 8 LAVLVFYLGFLISVGIYQ--GRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLP 65 ++V+V Y +++VG++ + F +AGR + W S A+ + +GL Sbjct: 29 ISVIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGLA 88 Query: 66 GFAFAAGLAA---IWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEK 122 G AAG+A W A+ +L +++ W + K VT +Y+ KR Sbjct: 89 GTGAAAGIATGGFEWNAL--ILVVLLGWVFVPIYI-----KAGVVTMPEYLRKRFGGQRI 141 Query: 123 WIRILGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSV 182 + L ++ + F + A G +N GLD L + I + YT+ GGL +V Sbjct: 142 QV-YLSVLSLVLYIFTKISADIFSGAIFINLALGLDLYLAIFILLAITALYTITGGLAAV 200 Query: 183 AYTDTVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAA 242 YTDT+Q ++M+L + + + + A + +T+ A Sbjct: 201 IYTDTLQTVIMLLGSFILTGFAFHEVGGYSAFVRKYMNAIPTVTSYGNTTVKKECYTPRA 260 Query: 243 IVFVI------AEFSWFFGYLGGMPQLSIRF-----MAIKDDKNAKLARNIGIGWTIIAY 291 F I + W G + G+ +S+ + + ++ +AK ++ G + Y Sbjct: 261 DSFHIFRDPLKGDLPW-PGLIFGLTIISLWYWCTDQVIVQRCLSAKNMSHVKAGCIMCGY 319 Query: 292 IGAL------MIGWIGIAIFGPN-GLKDPEQ--------------VMPSVMLKLFPPALA 330 + L M G I +F P + P+++++L P L Sbjct: 320 MKLLPMFLMVMPGMISRILFTEKVACTVPSECEKYCGTKVGCTNIAYPTLVVELMPNGLR 379 Query: 331 AVFITGAVAAMLSTADSLLILSSTEFSENILKPYIYKNEADPRKSLMVS----RLTTVSL 386 + ++ +A+++S+ S+ +ST F+ +I Y + K LM++ L + + Sbjct: 380 GLMLSVMLASLMSSLTSIFNSASTLFTMDI---YTKIRKKASEKELMIAGRLFMLVVIGV 436 Query: 387 GIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVIVILTLFWKR------FHGKAVPPTII 440 I + + S ++ + + +G + +L +F KR F G + I Sbjct: 437 SIAWVPIVQSAQSGQLFDYIQSITSYLGPPMRAVFLLAIFCKRVNEPGAFWGLIIGFLIG 496 Query: 441 AGLLFTVFWISSGLDAKVS--------VRLMNF-IVTFIVAIIATYAI 479 + T F +G + S V + F I+ F++ II AI Sbjct: 497 VSRMITEFAYGTGSCMEPSNCPTIICGVHYLYFAIILFVITIIVILAI 544 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.327 0.142 0.429 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 169975974 Number of Sequences: 2977 Number of extensions: 6928073 Number of successful extensions: 29246 Number of sequences better than 1.0e-10: 104 Number of HSP's better than 0.0 without gapping: 41 Number of HSP's successfully gapped in prelim test: 63 Number of HSP's that attempted gapping in prelim test: 28868 Number of HSP's gapped (non-prelim): 123 length of query: 484 length of database: 189,106,746 effective HSP length: 53 effective length of query: 431 effective length of database: 157,386,935 effective search space: 67833768985 effective search space used: 67833768985 T: 11 A: 40 X1: 15 ( 7.1 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 40 (21.7 bits) S2: 167 (69.5 bits)