BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0616 (ileS) DE:isoleucyl-tRNA synthetase (ileS)
(1067 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9V072|SYI_PYRAB ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 2213 0.0
sp|O58792|SYI_PYRHO ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 2081 0.0
sp|O27428|SYI_METTH ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 1111 0.0
sp|P46214|SYI_PYRFU ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 1109 0.0
sp|P26499|SYI_METTM ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 1104 0.0
sp|Q58357|SYI_METJA ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 1070 0.0
gi|11498241 isoleucyl-tRNA synthetase (ileS) [Archaeoglobus fulg... 1034 0.0
gb|AAF65673.1|AF208389_1 (AF208389) isoleucyl-tRNA synthetase [M... 992 0.0
sp|Q9YF67|SYI_AERPE ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 987 0.0
gb|AAK41020.1| Isoleucine-tRNA synthetase (ileS) [Sulfolobus sol... 831 0.0
emb|CAB57581.1| (Y18930) isoleucyl-tRNA synthetase [Sulfolobus s... 831 0.0
gb|AAG20324.1| (AE005106) isoleucyl-tRNA synthetase; IleS [Halob... 764 0.0
pir||T34946 probable isoleucyl-tRNA synthetase - Streptomyces co... 652 0.0
sp|O51773|SYI_BORBU ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 641 0.0
sp|P41368|SYIP_STAAU ISOLEUCYL-TRNA SYNTHETASE, MUPIROCIN RESIST... 640 0.0
sp|P56690|SYI_THETH ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 639 0.0
emb|CAC12008.1| (AL445065) isoleucyl-tRNA synthetase related pro... 625 e-178
pir||E75407 isoleucyl-tRNA synthetase - Deinococcus radiodurans ... 618 e-176
sp|O84022|SYI_CHLTR ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 614 e-174
sp|Q9Z972|SYI_CHLPN ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 611 e-173
pir||C81552 isoleucyl-tRNA synthetase CP0665 [imported] - Chlamy... 611 e-173
sp|Q9XDB4|SYI_FERPE ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 606 e-172
pir||F81719 isoleucyl-tRNA synthetase TC0288 [imported] - Chlamy... 600 e-170
sp|P46213|SYI_THEMA ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 573 e-162
sp|O83466|SYI_TREPA ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 568 e-160
gi|6319395 cytoplasmic isoleucyl-tRNA synthetase; Ils1p [Sacchar... 558 e-157
sp|Q9X7E5|SYI_MYCLE ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 553 e-156
gi|11429025 isoleucine-tRNA synthetase [Homo sapiens] >gi|730870... 553 e-156
gi|4504555 isoleucine-tRNA synthetase [Homo sapiens] >gi|7770072... 553 e-156
gi|11429023 isoleucine-tRNA synthetase [Homo sapiens] 553 e-156
sp|Q10765|SYI_MYCTU ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 549 e-155
gb|AAA34712.1| (M19992) isoleucyl-tRNA synthetase (EC 6.1.1.5) [... 549 e-155
sp|Q21926|SYI_CAEEL PROBABLE ISOLEUCYL-TRNA SYNTHETASE, CYTOPLAS... 535 e-150
sp|O13651|SYIC_SCHPO ISOLEUCYL-TRNA SYNTHETASE, CYTOPLASMIC (ISO... 526 e-148
gb|AAF51821.1| (AE003597) CG11471 gene product [alt 1] [Drosophi... 519 e-146
sp|P46215|SYI_SULAC ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 516 e-145
pir||T04047 isoleucine--tRNA ligase homolog F24G24.120 - Arabido... 513 e-144
sp|O66651|SYI_AQUAE ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 507 e-142
sp|P36422|SYI_TETTH ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 506 e-142
sp|Q45477|SYI_BACSU ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 499 e-140
sp|Q9ZCU4|SYI_RICPR ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 483 e-135
sp|P41972|SYI_STAAU ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 479 e-134
dbj|BAB06264.1| (AP001515) isoleucyl-tRNA synthetase [Bacillus h... 476 e-133
pdb|1FFY|A Chain A, Insights Into Editing From An Ile-Trna Synth... 476 e-133
sp|P73505|SYI_SYNY3 ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 453 e-126
sp|P43824|SYI_HAEIN ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 440 e-122
dbj|BAB10327.1| (AB017061) isoleucyl-tRNA synthetase [Arabidopsi... 432 e-120
sp|O26861|SYV_METTH VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 420 e-116
gb|AAC41448.1| (L37104) transfer RNA-Ile synthetase [Thermotoga ... 420 e-116
sp|Q58413|SYV_METJA VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 418 e-115
sp|P57249|SYI_BUCAI ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 416 e-115
sp|Q9ZHB3|SYI_STRPN ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 416 e-115
sp|P00956|SYI_ECOLI ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 412 e-113
pir||D71457 valine--tRNA ligase (EC 6.1.1.9) - Pyrococcus horiko... 411 e-113
pir||B83077 isoleucyl-tRNA synthetase PA4560 [imported] - Pseudo... 410 e-113
pir||D82293 isoleucyl-tRNA synthetase VC0682 [imported] - Vibrio... 406 e-112
pir||C82559 isoleucyl-tRNA synthetase XF2418 [imported] - Xylell... 405 e-111
pir||B81982 probable isoleucine--tRNA ligase (EC 6.1.1.5) NMA062... 404 e-111
sp|P18330|SYI_PSEFL ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 402 e-111
pir||G81036 isoleucyl-tRNA synthetase NMB1833 [imported] - Neiss... 397 e-109
pir||G75014 valyl-tRNA synthetase (vals) PAB1255 - Pyrococcus ab... 391 e-107
gi|11499806 valyl-tRNA synthetase (valS) [Archaeoglobus fulgidus... 389 e-106
sp|P46207|SYI_AQUPY ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 383 e-105
sp|P41257|SYI_CAMJE ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 382 e-104
pir||B81309 isoleucine--tRNA ligase (EC 6.1.1.5) Cj1061c [import... 380 e-104
sp|Q9ZJJ1|SYI_HELPJ ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 379 e-104
dbj|BAA01304.1| (D10483) isoleucyl-tRNA ligase [Escherichia coli] 378 e-103
sp|P75258|SYI_MYCPN ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 372 e-101
gb|AAD56932.1|AF180145_24 (AF180145) isoleucyl-tRNA synthetase [... 370 e-101
pir||D72206 valine--tRNA ligase (EC 6.1.1.9) - Thermotoga mariti... 369 e-100
sp|P56456|SYI_HELPY ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 368 e-100
gb|AAF49539.1| (AE003528) CG5414 gene product [Drosophila melano... 364 3e-99
dbj|BAA95147.1| (D28500) mitochondrial isoleucine tRNA synthetas... 363 4e-99
pir||G82894 isoleucyl-tRNA synthetase UU410 [imported] - Ureapla... 362 1e-98
sp|P47587|SYI_MYCGE ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 361 3e-98
sp|Q27707|SYI_NOSLO ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 347 4e-94
gi|8922356 hypothetical protein FLJ10326 [Homo sapiens] >gi|7022... 327 4e-88
gi|11426198 hypothetical protein FLJ10326 [Homo sapiens] 327 4e-88
emb|CAB75396.1| (AL139298) valyl tRNA synthetase [Streptomyces c... 323 9e-87
gi|6325217 nuclear encoded mitochondrial isoleucyl-tRNA syntheta... 318 2e-85
gb|AAG20602.1| (AE005130) valyl-tRNA synthetase; ValS [Halobacte... 316 9e-85
gb|AAA64890.1| (L38957) mitochondrial isoleucyl-tRNA synthetase ... 315 2e-84
sp|Q05873|SYV_BACSU VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 313 6e-84
dbj|BAB06757.1| (AP001517) valyl-tRNA synthetase [Bacillus halod... 310 5e-83
pir||SYBSVS valine--tRNA ligase (EC 6.1.1.9) - Bacillus stearoth... 308 2e-82
gb|AAK41179.1| Valyl-tRNA synthetase (valS) [Sulfolobus solfatar... 308 3e-82
sp|P11931|SYV_BACST VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 305 1e-81
pir||T41201 isoleucyl-trna synthetase - fission yeast (Schizosa... 302 2e-80
sp|P96142|SYV_THETH VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 298 2e-79
sp|P56000|SYV_HELPY VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 293 6e-78
pir||T19442 hypothetical protein C25A1.7a - Caenorhabditis elega... 291 2e-77
sp|P36420|SYV_LACCA VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 290 5e-77
emb|CAC11189.1| (AL445063) valyl-tRNA synthetase related protein... 286 7e-76
pir||G83167 valyl-tRNA synthetase PA3834 [imported] - Pseudomona... 283 6e-75
sp|Q55522|SYV_SYNY3 VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 280 7e-74
sp|P43834|SYV_HAEIN VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 274 3e-72
sp|Q9ZK61|SYV_HELPJ VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 270 8e-71
sp|O53175|SYV_MYCTU VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 253 9e-66
pir||E75554 valyl-tRNA synthetase - Deinococcus radiodurans (str... 252 1e-65
sp|P28350|SYV_NEUCR VALYL-TRNA SYNTHETASE, MITOCHONDRIAL PRECURS... 249 2e-64
pir||E82001 valyl-tRNA synthetase NMA0094 [imported] - Neisseria... 247 4e-64
pir||F81230 valyl-tRNA synthetase NMB0174 [imported] - Neisseria... 247 5e-64
sp|P57447|SYV_BUCAI VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 247 5e-64
sp|Q9ZCN6|SYV_RICPR VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 246 1e-63
pir||E82068 valyl-tRNA synthetase VC2503 [imported] - Vibrio cho... 245 2e-63
sp|O83998|SYV_TREPA VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 243 1e-62
pir||G81348 valine--tRNA ligase (EC 6.1.1.9) Cj0775c [imported] ... 242 2e-62
pir||H81686 valyl-tRNA synthetase TC0576 [imported] - Chlamydia ... 240 6e-62
sp|O84304|SYV_CHLTR VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 235 3e-60
gb|AAA24657.1| (J03497) valyl tRNA synthetase [Escherichia coli] 232 2e-59
sp|P07118|SYV_ECOLI VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 231 4e-59
emb|CAA29322.1| (X05891) valyl-tRNA synthetase [Escherichia coli] 229 9e-59
gb|AAA97155.1| (U14003) valyl-tRNA synthetase [Escherichia coli] 229 1e-58
sp|O51680|SYV_BORBU VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 227 5e-58
pir||C72565 probable valyl-tRNA synthetase APE1805 - Aeropyrum p... 227 5e-58
sp|P93736|SYV_ARATH VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 226 8e-58
sp|Q9WY15|SYL_THEMA LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE... 226 1e-57
sp|P49696|SYV_FUGRU VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 222 2e-56
sp|P47576|SYV_MYCGE VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 222 2e-56
gb|AAF63175.1|AC010657_11 (AC010657) T5E21.11 [Arabidopsis thali... 221 3e-56
emb|CAB60428.1| (AL110500) contains similarity to Pfam domain: P... 219 1e-55
gb|AAF58412.1| (AE003819) CG4062 gene product [Drosophila melano... 217 4e-55
sp|P75304|SYV_MYCPN VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 212 2e-53
pir||T39630 valine-tRNA ligase precursor, mitochondrial - fissio... 210 5e-53
gi|6321531 mitochondrial and cytoplasmic valyl-tRNA synthetase; ... 207 5e-52
gb|AAA35207.1| (J02719) valyl-tRNA synthetase [Saccharomyces cer... 207 6e-52
sp|O58698|SYL_PYRHO LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE... 205 2e-51
pir||H75133 leucyl-tRNA synthetase (leus) PAB1782 - Pyrococcus a... 204 4e-51
gi|6755953 valyl-tRNA synthetase 2 [Mus musculus] >gi|3986754|gb... 200 6e-50
pir||E82913 valyl-tRNA synthetase UU267 [imported] - Ureaplasma ... 200 8e-50
gb|AAD26531.1|AF087141_1 (AF087141) valyl-tRNA synthetase [Mus m... 198 2e-49
gb|AAA81332.1| (M98326) valyl-tRNA synthetase [Homo sapiens] 196 2e-48
sp|P26640|SYV_HUMAN VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 196 2e-48
gi|5454158 valyl-tRNA synthetase 2 [Homo sapiens] >gi|11417740|r... 195 2e-48
pir||A64379 isoleucine--tRNA ligase (EC 6.1.1.5) - Methanococcus... 194 4e-48
sp|Q58050|SYL_METJA LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE... 194 4e-48
sp|O67411|SYV_AQUAE VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 191 3e-47
gb|AAF50346.1| (AE003553) CG5660 gene product [Drosophila melano... 191 4e-47
pir||S17675 valine--tRNA ligase (EC 6.1.1.9) - human >gi|31545|e... 186 1e-45
pir||B82843 valyl-tRNA synthetase XF0134 [imported] - Xylella fa... 186 1e-45
pir||PN0474 valine--tRNA ligase (EC 6.1.1.9) (version 2) - human... 183 7e-45
pir||T51503 valine--tRNA ligase-like protein - Arabidopsis thali... 182 2e-44
dbj|BAB14164.1| (AK022665) unnamed protein product [Homo sapiens] 179 1e-43
sp|P36430|SYL_BACSU LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE... 174 6e-42
sp|Q94425|SYI_CIOIN PROBABLE ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCI... 171 3e-41
pir||D75307 leucyl-tRNA synthetase - Deinococcus radiodurans (st... 171 4e-41
sp|P07813|SYL_ECOLI LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE... 168 2e-40
gb|AAB40843.1| (U82598) leucine tRNA synthetase [Escherichia coli] 168 3e-40
pir||G82260 leucyl-tRNA synthetase VC0956 [imported] - Vibrio ch... 168 4e-40
emb|CAA29642.1| (X06331) leucyl-tRNA synthetase [Escherichia coli] 167 5e-40
dbj|BAB07000.1| (AP001518) leucyl-tRNA synthetase [Bacillus halo... 166 1e-39
dbj|BAA28842.1| (AB008528) Valyl tRNA Synthetase [Trichomonas va... 162 2e-38
sp|P73274|SYL_SYNY3 LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE... 162 2e-38
sp|Q9YD97|SYL_AERPE LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE... 156 1e-36
sp|O51267|SYL_BORBU LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE... 152 2e-35
pir||F81312 leucine--tRNA ligase (EC 6.1.1.4) Cj1091c [imported]... 151 5e-35
gi|11499997 leucyl-tRNA synthetase (leuS) [Archaeoglobus fulgidu... 150 6e-35
gb|AAG10490.1|AF279106_52 (AF279106) predicted leucyl-tRNA synth... 150 8e-35
sp|O27552|SYL_METTH LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE... 150 1e-34
gb|AAK40902.1| Leucyl-tRNA synthetase (leuS-2) [Sulfolobus solfa... 148 2e-34
emb|CAB57710.1| (Y18930) isoleucyl-trna synthetase [Sulfolobus s... 148 2e-34
sp|P57519|SYL_BUCAI LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE... 145 3e-33
pir||T27465 hypothetical protein Y87G2A.m - Caenorhabditis elegans 137 6e-31
sp|Q9ZJ63|SYL_HELPJ LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE... 134 4e-30
dbj|BAB15191.1| (AK025618) unnamed protein product [Homo sapiens] 130 1e-28
gb|AAK40823.1| Leucyl-tRNA synthetase (leuS-1) [Sulfolobus solfa... 129 1e-28
sp|P43827|SYL_HAEIN LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE... 125 2e-27
pir||T01968 isoleucine--tRNA ligase homolog T9A4.4 - Arabidopsis... 123 1e-26
pir||E82590 leucyl-tRNA synthetase XF2176 [imported] - Xylella f... 119 2e-25
sp|O84211|SYL_CHLTR LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE... 118 2e-25
sp|Q9Z930|SYL_CHLPN LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE... 115 2e-24
pir||A41882 leucine--tRNA ligase (EC 6.1.1.4) - Bacillus subtili... 109 2e-22
pir||F82899 leucyl-tRNA synthetase UU371 [imported] - Ureaplasma... 103 1e-20
sp|Q9Z987|SYV_CHLPN VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 101 5e-20
gb|AAB49280.1| (U60901) isoleucyl-tRNA-synthetase [Bacillus subt... 101 6e-20
pir||S77848 probable valine--tRNA ligase (EC 6.1.1.9) - Mycoplas... 97 9e-19
gb|AAD36946.1|AF069441_6 (AF069441) putative leucyl tRNA synthet... 96 2e-18
emb|CAC11908.1| (AL445065) leucyl-tRNA synthetase related protei... 96 3e-18
sp|P36432|SYV_HAEPA VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 96 3e-18
sp|O66680|SYLA_AQUAE LEUCYL-TRNA SYNTHETASE ALPHA SUBUNIT (LEUCI... 93 1e-17
dbj|BAB17162.1| (AP002868) putative leucyl-tRNA synthetase [Oryz... 93 2e-17
pir||F81974 leucine--tRNA ligase (EC 6.1.1.4) NMA0559 [similarit... 91 5e-17
pir||G81029 leucine--tRNA ligase (EC 6.1.1.4) NMB1897 [similarit... 90 9e-17
sp|Q9ZDB1|SYL_RICPR LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE... 90 2e-16
dbj|BAA28840.1| (AB008526) Valyl tRNA Synthetase [Trichomonas va... 89 3e-16
pir||E83148 leucyl-tRNA synthetase PA3987 [imported] - Pseudomon... 89 3e-16
dbj|BAA28841.1| (AB008527) Valyl tRNA Synthetase [Trichomonas va... 89 3e-16
gb|AAG20349.1| (AE005108) leucine-tRNA synthetase; LeuS [Halobac... 87 8e-16
sp|P37465|SYM_BACSU METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA ... 86 2e-15
pir||T30889 valine--tRNA ligase (EC 6.1.1.9) - Giardia lamblia >... 80 1e-13
pir||G81698 leucyl-tRNA synthetase TC0481 [imported] - Chlamydia... 79 2e-13
sp|O33925|SYM_THEMA METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA ... 79 3e-13
sp|O83595|SYL_TREPA LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE... 76 3e-12
gb|AAD50458.1|AF169967_1 (AF169967) LeuS [Flavobacterium johnson... 74 1e-11
sp|P47508|SYL_MYCGE LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE... 71 5e-11
dbj|BAA28843.1| (AB008529) Valyl tRNA Synthetase [Trichomonas va... 71 5e-11
dbj|BAA28844.1| (AB008530) Valyl tRNA Synthetase [Trichomonas va... 71 9e-11
>sp|Q9V072|SYI_PYRAB ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|7437558|pir||H75139 isoleucyl-tRNA synthetase (iles)
PAB0616 - Pyrococcus abyssi (strain Orsay)
>gi|5458344|emb|CAB49833.1| (AJ248285) isoleucyl-tRNA
synthetase (ileS) [Pyrococcus abyssi]
Length = 1067
Score = 2213 bits (5670), Expect = 0.0
Identities = 1067/1067 (100%), Positives = 1067/1067 (100%)
Query: 1 MIKEPEFREYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTA 60
MIKEPEFREYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTA
Sbjct: 1 MIKEPEFREYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTA 60
Query: 61 WNKIIKDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIK 120
WNKIIKDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIK
Sbjct: 61 WNKIIKDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIK 120
Query: 121 KCKEFALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRV 180
KCKEFALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRV
Sbjct: 121 KCKEFALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRV 180
Query: 181 LHWCPRCETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSA 240
LHWCPRCETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSA
Sbjct: 181 LHWCPRCETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSA 240
Query: 241 HPDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMD 300
HPDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMD
Sbjct: 241 HPDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMD 300
Query: 301 EYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDD 360
EYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDD
Sbjct: 301 EYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDD 360
Query: 361 QGKYTEGKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWF 420
QGKYTEGKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWF
Sbjct: 361 QGKYTEGKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWF 420
Query: 421 LKISKVKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGE 480
LKISKVKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGE
Sbjct: 421 LKISKVKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGE 480
Query: 481 IYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNG 540
IYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNG
Sbjct: 481 IYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNG 540
Query: 541 KDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAAS 600
KDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAAS
Sbjct: 541 KDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAAS 600
Query: 601 IVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWE 660
IVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWE
Sbjct: 601 IVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWE 660
Query: 661 NLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNS 720
NLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNS
Sbjct: 661 NLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNS 720
Query: 721 LISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKV 780
LISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKV
Sbjct: 721 LISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKV 780
Query: 781 FDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREMEFIRRI 840
FDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREMEFIRRI
Sbjct: 781 FDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREMEFIRRI 840
Query: 841 VEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQLNAKEVKVGRVEREL 900
VEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQLNAKEVKVGRVEREL
Sbjct: 841 VEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQLNAKEVKVGRVEREL 900
Query: 901 TIKPNFAKLGPEFKGDAKIIAKWINENGRELYEKGELTVEIDGKTFHLTREHIIVEEKLP 960
TIKPNFAKLGPEFKGDAKIIAKWINENGRELYEKGELTVEIDGKTFHLTREHIIVEEKLP
Sbjct: 901 TIKPNFAKLGPEFKGDAKIIAKWINENGRELYEKGELTVEIDGKTFHLTREHIIVEEKLP 960
Query: 961 DFFVSEEFEGGRVFVDKTLTRELIAEGLAREFVRRIQEMRKRLDLDVNDRIIVTIETTDE 1020
DFFVSEEFEGGRVFVDKTLTRELIAEGLAREFVRRIQEMRKRLDLDVNDRIIVTIETTDE
Sbjct: 961 DFFVSEEFEGGRVFVDKTLTRELIAEGLAREFVRRIQEMRKRLDLDVNDRIIVTIETTDE 1020
Query: 1021 NVELLKENLDYIMRETRADKIVFGKAKGYVVEWPEVQAKIGIEKVEE 1067
NVELLKENLDYIMRETRADKIVFGKAKGYVVEWPEVQAKIGIEKVEE
Sbjct: 1021 NVELLKENLDYIMRETRADKIVFGKAKGYVVEWPEVQAKIGIEKVEE 1067
>sp|O58792|SYI_PYRHO ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|7437549|pir||F71100 isoleucine--tRNA ligase (EC
6.1.1.5) - Pyrococcus horikoshii
>gi|3257481|dbj|BAA30164.1| (AP000004) 1066aa long
hypothetical isoleucyl-tRNA synthetase [Pyrococcus
horikoshii]
Length = 1066
Score = 2081 bits (5333), Expect = 0.0
Identities = 975/1066 (91%), Positives = 1042/1066 (97%)
Query: 1 MIKEPEFREYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTA 60
MIKEPEFR+Y P KLEEK+E+FW EN IY+K+KELRK+GPKYYFLDGPPYVSGAIHLGTA
Sbjct: 1 MIKEPEFRDYTPGKLEEKIEEFWKENNIYQKIKELRKNGPKYYFLDGPPYVSGAIHLGTA 60
Query: 61 WNKIIKDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIK 120
WNKIIKDMIIRFRTMQGYNVWRQPG+DMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIK
Sbjct: 61 WNKIIKDMIIRFRTMQGYNVWRQPGFDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIK 120
Query: 121 KCKEFALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRV 180
KCKEFALNNLKIMTEQFKMLGIWMDWD+PYMTIKNEYIESAWFTLK+AWEKGLLEKDKRV
Sbjct: 121 KCKEFALNNLKIMTEQFKMLGIWMDWDDPYMTIKNEYIESAWFTLKKAWEKGLLEKDKRV 180
Query: 181 LHWCPRCETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSA 240
LHWCPRCETALAEHEVRGEYKLRKDPSIYVKFP+EGKENEYLLIWTTTPWTLPANLAVSA
Sbjct: 181 LHWCPRCETALAEHEVRGEYKLRKDPSIYVKFPIEGKENEYLLIWTTTPWTLPANLAVSA 240
Query: 241 HPDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMD 300
HP+YDYVKVKVEFNG+EEYWILAKALVDKVLGEIGVKGEV+EEFKGRELEGLRY+H+LMD
Sbjct: 241 HPEYDYVKVKVEFNGKEEYWILAKALVDKVLGEIGVKGEVIEEFKGRELEGLRYIHVLMD 300
Query: 301 EYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDD 360
EYPRQKEF+EKYEWAHR+ILADFVTLEEGTGLVHTAPGHGEEDFEVG+KYGLP+YSP+DD
Sbjct: 301 EYPRQKEFREKYEWAHRIILADFVTLEEGTGLVHTAPGHGEEDFEVGKKYGLPIYSPVDD 360
Query: 361 QGKYTEGKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWF 420
QG+Y EGKWKGIYVKEADP+IIEHL+EKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWF
Sbjct: 361 QGRYVEGKWKGIYVKEADPQIIEHLKEKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWF 420
Query: 421 LKISKVKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGE 480
LK+SKVKD+IIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGE
Sbjct: 421 LKVSKVKDRIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGE 480
Query: 481 IYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNG 540
IYVVGSWRELVELAVAIEVNGERI+LPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNG
Sbjct: 481 IYVVGSWRELVELAVAIEVNGERIDLPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNG 540
Query: 541 KDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAAS 600
K+MRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAAS
Sbjct: 541 KEMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAAS 600
Query: 601 IVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWE 660
++AFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVE+AGRDTFRFYMLWATNPWE
Sbjct: 601 VIAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVEKAGRDTFRFYMLWATNPWE 660
Query: 661 NLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNS 720
NLKFSWKGVEQVRRMLNILWNVYVL++TYMSLDNFDPR + +EL FREEDKWILSRVNS
Sbjct: 661 NLKFSWKGVEQVRRMLNILWNVYVLSATYMSLDNFDPRNVKVEELAFREEDKWILSRVNS 720
Query: 721 LISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKV 780
LI EVENGIE+FYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEG+DPDKLAAYYTLWKV
Sbjct: 721 LIREVENGIETFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGDDPDKLAAYYTLWKV 780
Query: 781 FDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREMEFIRRI 840
FDVLLRL+APFTPYI EEIYQNL+RPF +ESVHMLDWPKVDE A+DE+LE+EMEFIRRI
Sbjct: 781 FDVLLRLMAPFTPYITEEIYQNLMRPFIGIESVHMLDWPKVDESAVDEDLEKEMEFIRRI 840
Query: 841 VEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQLNAKEVKVGRVEREL 900
VEAGSAARQ+A+IKLRYPVR+IIIET+DETVKKAVERLN ILRDQLNAKEV +G+VEREL
Sbjct: 841 VEAGSAARQKARIKLRYPVRKIIIETQDETVKKAVERLNYILRDQLNAKEVVIGKVEREL 900
Query: 901 TIKPNFAKLGPEFKGDAKIIAKWINENGRELYEKGELTVEIDGKTFHLTREHIIVEEKLP 960
T+KPNFAK+GPEFKGD++++AKWINE+G ELYEKGE+ VEI+GK FHLTREHIIVEEKLP
Sbjct: 901 TVKPNFAKVGPEFKGDSRLVAKWINEHGLELYEKGEVDVEIEGKKFHLTREHIIVEEKLP 960
Query: 961 DFFVSEEFEGGRVFVDKTLTRELIAEGLAREFVRRIQEMRKRLDLDVNDRIIVTIETTDE 1020
DF V+E+FEGGRV+VDKTLTREL+AEGLAREFVRRIQEMRKRLDLDVNDRI+VTIETTD+
Sbjct: 961 DFLVAEDFEGGRVYVDKTLTRELLAEGLAREFVRRIQEMRKRLDLDVNDRIVVTIETTDD 1020
Query: 1021 NVELLKENLDYIMRETRADKIVFGKAKGYVVEWPEVQAKIGIEKVE 1066
N ELL+ENLDYIMRETRA ++ F +AKGYVVEWPEVQAKIGIEKVE
Sbjct: 1021 NRELLQENLDYIMRETRAIEVRFEEAKGYVVEWPEVQAKIGIEKVE 1066
>sp|O27428|SYI_METTH ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|7437550|pir||H69049 isoleucine--tRNA ligase (EC
6.1.1.5) - Methanobacterium thermoautotrophicum (strain
Delta H) >gi|2622484|gb|AAB85852.1| (AE000900)
isoleucyl-tRNA synthetase [Methanobacterium
thermoautotrophicum]
Length = 1044
Score = 1111 bits (2842), Expect = 0.0
Identities = 550/1068 (51%), Positives = 741/1068 (68%), Gaps = 58/1068 (5%)
Query: 2 IKEPEFREYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAW 61
I+E E + Y P ++EEKV+ FW E +IY +VKELR+D P+Y FLDGPPY SG IHLGTAW
Sbjct: 3 IQEAE-KSYRPHRIEEKVQSFWEERDIYERVKELREDRPRYSFLDGPPYCSGRIHLGTAW 61
Query: 62 NKIIKDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKK 121
NKI+KD +RF++M+G+NV RQPG+D HGLPIE KVE LG+++KK+IE+KIG+E F+ K
Sbjct: 62 NKIMKDTYLRFKSMKGFNVRRQPGWDTHGLPIEHKVEGLLGVRSKKDIEDKIGIEEFVNK 121
Query: 122 CKEFALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVL 181
C+EFA+ N +MT QF+ LG+WMDWD+PY+T Y+ES W+TLKRA EK LL +D RV+
Sbjct: 122 CREFAVENKAVMTGQFQRLGVWMDWDDPYVTFDPAYMESCWWTLKRAHEKDLLVRDLRVI 181
Query: 182 HWCPRCETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAH 241
WCPRCETALA E+ +Y ++DPSIYVKFPV G + ++L+WTTTPWTLPAN+AV+ H
Sbjct: 182 TWCPRCETALALAEI--DYHDKEDPSIYVKFPVSG--DTHILVWTTTPWTLPANMAVAVH 237
Query: 242 PDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDE 301
PD++Y +++ E +I+A+ALV+KVLGE + E+++ KG ELEGL Y H L DE
Sbjct: 238 PDFEYAYARLD----GETYIMAEALVEKVLGE---EAEILKRVKGTELEGLTYRHPLDDE 290
Query: 302 YPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQ 361
P +E + HRVIL D VTL EGTG VHTAPGHG EDFE+G+KYGL V P+D+
Sbjct: 291 VPLHREIE------HRVILGDHVTLTEGTGCVHTAPGHGPEDFEIGKKYGLEVICPVDEA 344
Query: 362 GKYTE--GKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQW 419
G +TE GK+ G +VK+AD II LR KG L+KAG I H+Y CWRCKTP+I+ AT+QW
Sbjct: 345 GIFTEEAGKYSGRFVKDADEDIIADLRSKGLLLKAGTISHRYGFCWRCKTPIIYLATEQW 404
Query: 420 FLKISKVKDKIIKENDEKVTWYPDWV-KIRFDNGVRDSGDWVISRQRYWGIPLPIWQSED 478
FLKI+++KDK+++E D +V W P W + RF N + ++ DW ISRQRYWGIP+PIW E+
Sbjct: 405 FLKITEIKDKMLRELD-RVQWVPSWAGESRFRNWIENARDWTISRQRYWGIPIPIWICEE 463
Query: 479 GE-IYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIK 537
+ I+VVGS EL ELAV E+ G+ I HRP+VD +++
Sbjct: 464 CDSIHVVGSIDELRELAVEGELEGDFI----------------------HRPHVDRIVLE 501
Query: 538 VN--GKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYS 595
G M+R DV+DVW DSG+A WA+L YP ELF + +P DFI EG DQ WFYS
Sbjct: 502 CGECGGRMKRTPDVLDVWIDSGVAGWAALHYPSETELFREWFPYDFITEGHDQTRGWFYS 561
Query: 596 QQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWA 655
Q ++A D VPYRRV MHG+ LDE+G KMSKSLGN++ PE+V+E+ G D RFY+LW
Sbjct: 562 QLGCGVIALDEVPYRRVLMHGFTLDEEGRKMSKSLGNVVEPEDVIEKYGADVLRFYLLWE 621
Query: 656 TNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWIL 715
PWE+LKF W + V +M NILWNVYV A+TYMSLD F P + ++L FR+ED+WIL
Sbjct: 622 NKPWEDLKFVWDELRNVNKMFNILWNVYVFATTYMSLDRFQPGDHSAEDLSFRDEDRWIL 681
Query: 716 SRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYY 775
SR+NS+ +V IE+ + +ATR +++F+VEDLSRWY+RLIR R W+E +DPDKLAAY+
Sbjct: 682 SRINSVALKVTEAIENLHFHRATREIHDFIVEDLSRWYIRLIRSRTWIERDDPDKLAAYH 741
Query: 776 TLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPF--TNVESVHMLDWPKVDEKAIDEELERE 833
TL+ V L+ L+P P++ E+IYQNL+R + ES+HMLDW +DE A+D +LE +
Sbjct: 742 TLYTVLKTLIVTLSPMAPHVCEDIYQNLVRGAEPDSPESIHMLDW-ILDEGAVDSQLEAD 800
Query: 834 MEFIRRIVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQLNAKEVKV 893
M+ +R I+EA + AR A+ KLR+PVR +++ +EDE V KA E L ++ +Q NAK +K
Sbjct: 801 MDIVREIIEACARARDTARYKLRWPVREMVVVSEDEGVLKAAESLKNVIAEQANAKSIKT 860
Query: 894 GR--VERELTIKPNFAKLGPEFKGDAKIIAKWI-----NENGRELYEKGELTVEIDGKTF 946
+ ++ +PN A LGP + D ++ + + + L GE TVE DGK F
Sbjct: 861 STEFPDMKIIARPNPATLGPRLRQDIPLVMRELEGADGSAVKAALDSDGEFTVETDGKKF 920
Query: 947 HLTREHIIVEEKLPDFFVSEEFEGGRVFVDKTLTRELIAEGLAREFVRRIQEMRKRLDLD 1006
LT E I+ E +LP+ VS +F+GG VF+D LT E+++E +ARE VRRIQ+MRK LDLD
Sbjct: 921 KLTSEDIVFETELPENIVSAQFDGGSVFIDTELTPEIMSEAMARELVRRIQDMRKDLDLD 980
Query: 1007 VNDRIIVTIETTDENVELLKENLDYIMRETRADKIVFGKAK-GYVVEW 1053
V I V+++ ++E EL + ++I E RA + F ++ Y EW
Sbjct: 981 VEASIEVSVKCSEEFRELTEPQREFIENEVRASTLSFDYSELEYTKEW 1028
>sp|P46214|SYI_PYRFU ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|598367|gb|AAC41446.1| (L37105) transfer RNA-Ile
synthetase [Pyrococcus furiosus]
Length = 546
Score = 1109 bits (2836), Expect = 0.0
Identities = 515/546 (94%), Positives = 536/546 (97%)
Query: 87 DMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIMTEQFKMLGIWMDW 146
D HGLPIEVKVEQALGLKTKKEIEEKIGVENF++KCKEFALNNL+IMTEQFKMLG+WMDW
Sbjct: 1 DTHGLPIEVKVEQALGLKTKKEIEEKIGVENFVQKCKEFALNNLRIMTEQFKMLGVWMDW 60
Query: 147 DNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHEVRGEYKLRKDP 206
DNPYMTIKNEYIESAWFTLK AWEKGLLEKDKRVLHWCPRCETALAEHEVRGEYKLRKDP
Sbjct: 61 DNPYMTIKNEYIESAWFTLKWAWEKGLLEKDKRVLHWCPRCETALAEHEVRGEYKLRKDP 120
Query: 207 SIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVKVKVEFNGREEYWILAKAL 266
SIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSA PDYDYVKV V+ NGREEYWILAKAL
Sbjct: 121 SIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSALPDYDYVKVGVDLNGREEYWILAKAL 180
Query: 267 VDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFKEKYEWAHRVILADFVTL 326
V+KVLG+IGVKGEVVEEFKG+ELEGLRYVHILMDEYPRQKEF+EKYEW HRVILADFVTL
Sbjct: 181 VEKVLGDIGVKGEVVEEFKGKELEGLRYVHILMDEYPRQKEFREKYEWVHRVILADFVTL 240
Query: 327 EEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTEGKWKGIYVKEADPKIIEHLR 386
EEGTGLVHTAPGHGEEDFEVGQKYGLPVYSP+DDQGKY EGKWKG+YVKEADP+IIEHL+
Sbjct: 241 EEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPVDDQGKYVEGKWKGVYVKEADPQIIEHLK 300
Query: 387 EKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKDKIIKENDEKVTWYPDWVK 446
EKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLK+SKVK+KIIKENDEKVTWYP+WVK
Sbjct: 301 EKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKVSKVKEKIIKENDEKVTWYPEWVK 360
Query: 447 IRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVELAVAIEVNGERIEL 506
IRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSW+ELVEL VAIEVN ERI+L
Sbjct: 361 IRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWKELVELTVAIEVNSERIDL 420
Query: 507 PESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGY 566
PESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGK+MRRVKDVVDVWFDSGIASWASLGY
Sbjct: 421 PESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKEMRRVKDVVDVWFDSGIASWASLGY 480
Query: 567 PRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKM 626
PRNKELFEKLWPADFIVEGEDQVTKWFYSQQAAS++AFDTVPYR VAMHGYVLDEKGDKM
Sbjct: 481 PRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASVIAFDTVPYRAVAMHGYVLDEKGDKM 540
Query: 627 SKSLGN 632
SKSLGN
Sbjct: 541 SKSLGN 546
>sp|P26499|SYI_METTM ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|68525|pir||SYEXI isoleucine--tRNA ligase (EC 6.1.1.5)
[validated] - Methanobacterium thermoautotrophicum
(strain Marburg) >gi|149728|gb|AAA72950.1| (M59245)
transfer RNA-Ile synthetase [Methanobacterium
thermoautotrophicum]
Length = 1045
Score = 1104 bits (2824), Expect = 0.0
Identities = 544/1068 (50%), Positives = 744/1068 (68%), Gaps = 58/1068 (5%)
Query: 2 IKEPEFREYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAW 61
I+E E + Y P +EEKV+ FW E +IY +VKELR++GP+Y FLDGPPY SG IHLGTAW
Sbjct: 3 IQEAE-KSYKPHVIEEKVQSFWEERDIYERVKELREEGPRYSFLDGPPYCSGRIHLGTAW 61
Query: 62 NKIIKDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKK 121
NKI+KD +RF++M+G+NV RQPG+D HGLPIE KVE LG+++KK+IE+KIG+E F++K
Sbjct: 62 NKIMKDSYLRFKSMRGFNVRRQPGWDTHGLPIEHKVEGILGVRSKKDIEDKIGIEEFVRK 121
Query: 122 CKEFALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVL 181
C+EFA+ N +MT QF+ LG+WMDWD+PY+T Y+ES W+TLKRA EK LL +D RV+
Sbjct: 122 CREFAMENKAVMTSQFQRLGVWMDWDDPYVTFDPAYMESCWWTLKRAHEKDLLLRDLRVI 181
Query: 182 HWCPRCETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAH 241
WCPRCETALA E+ +Y ++DPSIYVKFPV G + Y+L+WTTTPWTLPAN+AV+ H
Sbjct: 182 TWCPRCETALALAEI--DYHEKEDPSIYVKFPVSG--DTYILVWTTTPWTLPANMAVAVH 237
Query: 242 PDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDE 301
PD+DY +++ E +I+A+ALV+KVLGE + E+++ +G ELEGL Y H L +E
Sbjct: 238 PDFDYAHTRLD----GETYIMAEALVEKVLGE---EAEIIKTVRGSELEGLTYRHPLDEE 290
Query: 302 YPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQ 361
P ++ + HRVIL D VTL EGTG VHTAPGHG EDFE+G++YGLPV+ P+D+
Sbjct: 291 VPCHRDME------HRVILGDHVTLTEGTGCVHTAPGHGPEDFEIGKEYGLPVFCPVDEA 344
Query: 362 GKYTE--GKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQW 419
G +TE GK++G++VK+AD II+ LR K L++A I H+Y CWRCKTP+I+ AT+QW
Sbjct: 345 GVFTEDAGKYRGLFVKDADSDIIDDLRSKNLLLRAETISHRYGFCWRCKTPIIYLATEQW 404
Query: 420 FLKISKVKDKIIKENDEKVTWYPDWV-KIRFDNGVRDSGDWVISRQRYWGIPLPIWQSED 478
FLKI+++KDK++ E D +V W P W + RF N + ++ DW ISRQRYWGIP+PIW ED
Sbjct: 405 FLKITEIKDKMLSELD-RVQWIPSWAGESRFRNWIENARDWTISRQRYWGIPIPIWVCED 463
Query: 479 GE-IYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIK 537
+ I+VVGS EL ELAV ++ G+ I HRP+VD I++
Sbjct: 464 CDSIHVVGSIGELRELAVEGQLEGDFI----------------------HRPHVDRIILE 501
Query: 538 VN--GKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYS 595
G M+R DV+DVW DSG+A WA+L YPR KELF + +P DFI EG DQ WFYS
Sbjct: 502 CGRCGGRMKRTPDVLDVWIDSGVAGWAALHYPREKELFSEWFPYDFITEGHDQTRGWFYS 561
Query: 596 QQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWA 655
Q ++A D PYRRV MHG+ LDE+G KMSKSLGN++ PE+V+E+ G D RFY+LWA
Sbjct: 562 QLGCGVIALDETPYRRVLMHGFTLDEEGRKMSKSLGNVVEPEDVIEKYGADVLRFYLLWA 621
Query: 656 TNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWIL 715
PWE+LKF W ++ V +M NILWNVYV A+TYMSLD F P ++L FR+ED+WI+
Sbjct: 622 NKPWEDLKFVWDELKNVNKMFNILWNVYVFATTYMSLDRFQPGDHELEDLHFRDEDRWII 681
Query: 716 SRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYY 775
SRVNS+ +V +++ + +ATR +++F+VEDLSRWY+RLIR R W+E +DPDKLAAY+
Sbjct: 682 SRVNSVALKVTEALDNLHFHRATREIHDFIVEDLSRWYIRLIRSRTWIERDDPDKLAAYH 741
Query: 776 TLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPF--TNVESVHMLDWPKVDEKAIDEELERE 833
+L+ L+ L+P P++ E+IYQNL+R + ES+HMLDW V E A+D +LE E
Sbjct: 742 SLYTALKTLIVTLSPIAPHVCEDIYQNLVRGAEPDSPESIHMLDW-MVSEDAVDGKLEAE 800
Query: 834 MEFIRRIVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQLNAKEVKV 893
M+ +R I+EA + AR A+ KLR+PVR I++ +ED+ V +A E L ++ +Q NAK ++
Sbjct: 801 MDIVREIIEACARARDTARYKLRWPVREIVVVSEDDKVLEAAESLKGVIAEQANAKSIRT 860
Query: 894 GRVERELTI--KPNFAKLGPEFKGDAKIIAKWINE-NGRE----LYEKGELTVEIDGKTF 946
++ I KPN A LGP+ + D + + + E +G E L +G V++DG+
Sbjct: 861 STEFPDMRIIAKPNPATLGPKLRQDMPPVMRKLEEADGAEVKAALESEGSFRVDLDGRII 920
Query: 947 HLTREHIIVEEKLPDFFVSEEFEGGRVFVDKTLTRELIAEGLAREFVRRIQEMRKRLDLD 1006
L + II E +LP+ V+ +FEGG VFVD LT E+++E +ARE VRRIQ+MRK LDLD
Sbjct: 921 VLEPDDIIFETELPENIVNAQFEGGSVFVDTELTPEIMSEAMARELVRRIQDMRKDLDLD 980
Query: 1007 VNDRIIVTIETTDENVELLKENLDYIMRETRADKIVFGKAK-GYVVEW 1053
V RI V+++ + E EL + +++ E RA + F + Y EW
Sbjct: 981 VEARIEVSVKCSPEFRELTEPQREFVENEVRASHLSFDYTELEYTKEW 1028
>sp|Q58357|SYI_METJA ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|2129087|pir||C64418 isoleucine--tRNA ligase (EC
6.1.1.5) - Methanococcus jannaschii
>gi|1591614|gb|AAB98949.1| (U67538) isoleucyl-tRNA
synthetase (ileS) [Methanococcus jannaschii]
Length = 1039
Score = 1070 bits (2738), Expect = 0.0
Identities = 544/1071 (50%), Positives = 736/1071 (67%), Gaps = 57/1071 (5%)
Query: 13 KKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRF 72
++L++K++KFW EN+IY+KVK+ + ++YF+DGPPY SGAIHLGTAWNKIIKD +RF
Sbjct: 10 RELDKKIKKFWEENDIYQKVKKKNERNKEFYFVDGPPYCSGAIHLGTAWNKIIKDTYLRF 69
Query: 73 RTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKI 132
+ MQGYNV + G+DMHGLPIEVKVE G+K KKEIE KIGV+ FI+KCKEFAL + +I
Sbjct: 70 KRMQGYNVLDKAGWDMHGLPIEVKVENEFGIKNKKEIETKIGVKQFIEKCKEFALKHKEI 129
Query: 133 MTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALA 192
M +QFK LG+W+DW+N YM I EY+E W+TLK A EKGLL +D RV++WCPRCETALA
Sbjct: 130 MEKQFKNLGVWLDWENAYMPITKEYMEIGWWTLKVAHEKGLLTRDLRVVYWCPRCETALA 189
Query: 193 EHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVKVKVE 252
EHEVRGEYK DPS+YVKF + +EN Y++IWTTTPWTL ANLAV+ HPDYDY V+VE
Sbjct: 190 EHEVRGEYKEVYDPSVYVKFRLANEENTYIVIWTTTPWTLVANLAVTVHPDYDYAYVEVE 249
Query: 253 FNGREEYWILAKALVDKVLGEI----GVKG-EVVEEFKGRELEGLRYVHILMDEYPRQKE 307
F+ ++E WI+A+ LV++V+ + +K +++++ KG+ELEG++Y+H L++E RQKE
Sbjct: 250 FDDKKEVWIIAEKLVEEVINKAKKFHNIKNYKIIKKVKGKELEGIKYIHPLLEENERQKE 309
Query: 308 FKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTEG 367
F E E AH VIL + VTLE GTGLVHTAPGHGEEDFEVG+KY LP+YSP+DD+GKY EG
Sbjct: 310 FAE-LENAHTVILGEHVTLEGGTGLVHTAPGHGEEDFEVGKKYNLPIYSPIDDEGKYVEG 368
Query: 368 KWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVK 427
KWKG++VK+AD +IIE L+ KG LV AG+I+H YPHCWRCKTPL+FRAT+QWFL+ISK+K
Sbjct: 369 KWKGVFVKDADAEIIETLKNKGLLVYAGKIKHSYPHCWRCKTPLLFRATEQWFLEISKIK 428
Query: 428 DKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSED-GEIYVVGS 486
D II E+ + V W P WV+ R+ NGV+ GDW ISRQRYWGIP+P+W E G+ VVGS
Sbjct: 429 DNII-EHAKTVQWIPHWVETRYINGVKFVGDWNISRQRYWGIPIPVWVCEKCGKYIVVGS 487
Query: 487 WRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVN-GKDMRR 545
EL EEK+ +E DLH+P VD ++ G +M+R
Sbjct: 488 VEEL--------------------EEKMINKDEVGEINDLHKPTVDKIKLRCECGGEMKR 527
Query: 546 VKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVAFD 605
V DV+DVWFDSG+A +AS+G ++L ADFI EG DQVTKWFYSQ A S + F+
Sbjct: 528 VPDVLDVWFDSGLAPYASIG-------VKELKKADFITEGHDQVTKWFYSQHALSAIVFN 580
Query: 606 TVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENLKFS 665
+PY++ MHG+ LDE GDKMSKSLGN++ P++VVE+ G D RFY+L A WE+L+F
Sbjct: 581 DIPYKKCLMHGFTLDEHGDKMSKSLGNVVNPDDVVEKYGADLLRFYLLSANKVWEDLRFV 640
Query: 666 WKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPF---REEDKWILSRVNSLI 722
W ++ V + N LWN Y+ A YM LDNF PDE F ++ED+WI+SR+NS+
Sbjct: 641 WSEMDDVLSLFNTLWNAYMFAVNYMVLDNF-----KPDEKYFEYLKDEDRWIVSRINSVA 695
Query: 723 SEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFD 782
+E Y T L +F++ DLSRWY+RLIR R W E +D DKLAAY TL+ V
Sbjct: 696 KIAIENLEVPYFHTYTWTLKDFILNDLSRWYIRLIRDRTWKEKDDADKLAAYQTLYYVLL 755
Query: 783 VLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREMEFIRRIVE 842
L +LAP P+ AE IYQNL ++E ++ +VDE+ IDEELER+M +R +V+
Sbjct: 756 KLATILAPVAPHTAEAIYQNL--KTEDMEESIFMNKIEVDEEFIDEELERDMAIVRDVVD 813
Query: 843 AGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQLNAKEVKVGRVE-RELT 901
A R R K LRYP++ I I +E VKKAVER I+++Q N K +K G VE +
Sbjct: 814 AIYRGRDRIKYTLRYPLKEITIAGGEE-VKKAVERFEYIIKEQGNVKNIKFGEVEGSKYI 872
Query: 902 IKPNFAKLGPEFKGDAKIIAKWINE-NGRELYEK-GELTVEIDGKTFHLTREHIIVEEKL 959
IKPN+ +LG ++ + + + +N+ + +EL E+ E V +DG + + E++ + ++
Sbjct: 873 IKPNYRELGKRYRSEVPKVVEALNKADAKELMERLKEGAVILDG--YEIKPEYVEIRLEI 930
Query: 960 PDFFVSEEFEGGRVFVDKTLTRELIAEGLAREFVRRIQEMRKRLDLDVNDRIIVTIETTD 1019
P+ EF G VF++ +T +LI EGL RE +RRIQ MRK +DLD+ ++I + +E D
Sbjct: 931 PEHIAGVEFSKGTVFINTEITDDLIKEGLMREVIRRIQAMRKDMDLDIEEKIKIKVEGID 990
Query: 1020 ENVELLKENLDYIMRETRADKIVFGKAKGYVVEWP---EVQAKIGIEKVEE 1067
++ KE ++ +R D+I K + ++ P + KI IE++ +
Sbjct: 991 --LDEFKEIIEREVRGQFVDEIKADYEKDWEIKTPNGEKYNVKIAIERINK 1039
>gi|11498241 isoleucyl-tRNA synthetase (ileS) [Archaeoglobus fulgidus]
>gi|3122898|sp|O29622|SYI_ARCFU ISOLEUCYL-TRNA SYNTHETASE
(ISOLEUCINE--TRNA LIGASE) (ILERS) >gi|7437551|pir||A69329
probable isoleucine--tRNA ligase (EC 6.1.1.5) -
Archaeoglobus fulgidus >gi|2649988|gb|AAB90608.1|
(AE001061) isoleucyl-tRNA synthetase (ileS)
[Archaeoglobus fulgidus]
Length = 1018
Score = 1034 bits (2644), Expect = 0.0
Identities = 535/1068 (50%), Positives = 713/1068 (66%), Gaps = 67/1068 (6%)
Query: 9 EYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDM 68
+Y PK +E ++ KFW +N+IYRKVKE K G K+YF+DGPPY +G IHLGTAWNK++KD
Sbjct: 5 KYSPKDVESEIFKFWEDNDIYRKVKE--KGGRKFYFVDGPPYTTGRIHLGTAWNKVLKDT 62
Query: 69 IIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALN 128
I+R++ M G+ PG+DMHGLPIEVKVEQ LG +TK++IE G++ FI++C +AL
Sbjct: 63 ILRYKRMMGFAPTDTPGWDMHGLPIEVKVEQELGFRTKRDIES-FGIDKFIERCMNYALA 121
Query: 129 NLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCE 188
N MTEQFK L +WMDW+NPYMTIK EY+ +AWF +KRA E+GLLE+ K V++WC RCE
Sbjct: 122 NKDAMTEQFKSLAVWMDWENPYMTIKAEYMNAAWFAIKRAHERGLLERKKMVVNWCHRCE 181
Query: 189 TALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVK 248
TALA+ EV EY +DPSIYVKFPV+G+++ Y++IWTTTPWTLPAN+AV+ HP +Y K
Sbjct: 182 TALADAEV--EYWDEEDPSIYVKFPVKGEKDTYIVIWTTTPWTLPANMAVAVHPSLEYAK 239
Query: 249 VKVEFNGREEYWILAKALVDKVLGEIGVKG-EVVEEFKGRELEGLRYVHILMDEYPRQKE 307
+ +G+ EY ILAK L D VLG+ EVVE + G +LEGL Y H L DE P QK
Sbjct: 240 FRAVKDGKVEYLILAKELADSVLGKGDYDSWEVVETYLGEDLEGLEYEHPLADEVPLQK- 298
Query: 308 FKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTE- 366
W H+V ADFVT E TG VH APGHG ED+E+G + GL V++P+DD+G YTE
Sbjct: 299 -----NWKHQVFFADFVT-AENTGCVHIAPGHGVEDYELGVEKGLEVFNPVDDRGVYTEE 352
Query: 367 -GKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISK 425
GK+ G +VKEA+ II+ L K L+ I H+Y HCWRCKTP+I+RAT+QWF+KIS+
Sbjct: 353 AGKYAGKHVKEANDDIIDDLYRKDLLLAEERIVHRYGHCWRCKTPIIYRATEQWFIKISE 412
Query: 426 VKDKIIKENDEKVTWYPDWV-KIRFDNGVRDSGDWVISRQRYWGIPLPIWQSED-GEIYV 483
+KD++++E D KV W P+W RF + V ++ DW ISRQRYWGIP+P+W E GE+ V
Sbjct: 413 LKDEMLEEID-KVMWIPEWAGSARFKDWVSNAKDWCISRQRYWGIPIPVWICEKCGEMKV 471
Query: 484 VGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVN-GKD 542
VGS E+ +E L DLHRP +DA G
Sbjct: 472 VGSINEI------------------EWENDL----------DLHRPKIDAVTFSCQCGGV 503
Query: 543 MRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIV 602
MRRV DV DVWFDSG+ASW S+ YP K+ FE+LWPADFI EG DQ WFYSQ S+V
Sbjct: 504 MRRVPDVFDVWFDSGVASWGSIAYPLRKDKFEELWPADFITEGHDQTRGWFYSQLGTSVV 563
Query: 603 AFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENL 662
FD PY+ V MHG+ LDE+G KMSKSLGN++ PEEVV + G D FR Y+L++ PWE+L
Sbjct: 564 CFDKAPYKAVLMHGFTLDEQGRKMSKSLGNVVEPEEVVGQIGVDGFRLYVLYSA-PWEDL 622
Query: 663 KFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLI 722
+FSW+ + RMLN++WN A TYMSLDN+ ++ + ED+WILSR+ S I
Sbjct: 623 RFSWEEARNINRMLNVVWNAVRFAHTYMSLDNYS----FGEKGELKIEDRWILSRLESFI 678
Query: 723 SEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFD 782
E +E + + + RA ++F VED SRWY+++IR R+W E + P KLAAYYT+++V D
Sbjct: 679 KEANEAMEGYQVHRVVRAFFDFFVEDFSRWYIQIIRPRVWEERDSPSKLAAYYTMFRVID 738
Query: 783 VLLRLLAPFTPYIAEEIYQNLIRPF-TNVESVHMLDWPKVDEKAIDEELEREMEFIRRIV 841
LR +APF P IAE YQ++++ F ES+ M ++ + + ID ELE M+ + IV
Sbjct: 739 RSLRAIAPFAPLIAEWFYQHVVKEFREGEESIFMEEYSTAEVEMIDGELEAAMKVAKEIV 798
Query: 842 EAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQLNAKEVK-VGRVEREL 900
EA + AR +AK KLR+P+R ++IE+ E V+KAVE L + Q N K+V+ V E+E+
Sbjct: 799 EAAANARNKAKRKLRWPLRELVIESGSEKVRKAVEMLEETILSQCNVKQVRVVDSFEKEI 858
Query: 901 TIKPNFAKLGPEFKGDAKIIAKWINENGRELYEKGELT-VEIDGKTFHLTREHIIVEEKL 959
IKPN+ +GP K A AK++ + +E+ EK VE+D K + I+V+ +L
Sbjct: 859 EIKPNYKYIGPLLKEKAGEFAKYV-ASLKEIPEKLVFDGVELDPK------QAIVVDYRL 911
Query: 960 PDFFVSEEFEGGRVFVDKTLTRELIAEGLAREFVRRIQEMRKRLDLDVNDRIIVTIETTD 1019
P+ + EF GG V++ K L EL+ E ARE +RRIQEMRK LDLDV + I T+E
Sbjct: 912 PEGYEYAEFSGGVVYIYKELDDELVREAFAREVIRRIQEMRKELDLDVEEFIETTVEM-- 969
Query: 1020 ENVELLKENLDYIMRETRADKIVFGKAKGYVVEW--PEVQAKIGIEKV 1065
+ EL+K DYI ETR+ K+VFGKA+GYV EW + KIGI+++
Sbjct: 970 -DAELVKGWEDYIKSETRSQKLVFGKAEGYVREWNIEGKKVKIGIKRL 1016
>gb|AAF65673.1|AF208389_1 (AF208389) isoleucyl-tRNA synthetase [Methanosarcina barkeri]
Length = 1058
Score = 992 bits (2536), Expect = 0.0
Identities = 523/1093 (47%), Positives = 714/1093 (64%), Gaps = 65/1093 (5%)
Query: 1 MIKEPEFREYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTA 60
MIKE + Y+ +++E+K+ + W +++ YRK +E RK G + +F+DGPPY +G IHLGTA
Sbjct: 1 MIKEITAK-YNAEQIEKKITQLWKDSDAYRKTREHRKTGKRLFFVDGPPYTTGHIHLGTA 59
Query: 61 WNKIIKDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIK 120
WNKIIKD I+R+ +M N+ +PG+DMHGLPIEVKVE LG K+KK+IE GVENFI+
Sbjct: 60 WNKIIKDSILRYYSMNNRNILERPGWDMHGLPIEVKVEGVLGFKSKKDIES-FGVENFIE 118
Query: 121 KCKEFALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRV 180
KCKEFA+N + MTEQF+ LG+WM W+ PYMT+K++YIE+AW+TLK+A EK LL+ KR
Sbjct: 119 KCKEFAINQKQEMTEQFQRLGVWMQWEAPYMTLKDDYIEAAWWTLKQASEKNLLDVGKRS 178
Query: 181 LHWCPRCETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSA 240
++WCPRCETA+A+ EV EY R DPSIYVKF ++G+EN +++IWTTTPWT+PAN+AV+
Sbjct: 179 VNWCPRCETAIADSEV--EYAERTDPSIYVKFKIKGEENTFIVIWTTTPWTIPANVAVAV 236
Query: 241 HPDYDYVKVK-VEFNGREEYWILAKALVDKVLGEIG-VKGEVVEEFKGRELEGLRYVHIL 298
HP ++Y K + + +G +E I A L++ VL + V EV+E G +L L Y +
Sbjct: 237 HPGFEYSKFRAIRQDGSDEILIAATDLIENVLRQGRYVDYEVLETMLGEDLTKLEYESPV 296
Query: 299 MDEYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPL 358
D P Q E K H + LAD+VT E TG VH APGHG +DF VG KY LP+ P+
Sbjct: 297 GDLVPVQNEIK------HGIYLADYVTAEN-TGCVHIAPGHGMDDFNVGVKYNLPILCPV 349
Query: 359 DDQGKYTE--GKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRAT 416
G YTE G++ G V+EA+P +IE LR++ L+ G + H+Y HCWRCKTP+I+ AT
Sbjct: 350 GPNGAYTEEAGEYAGKNVREANPIVIEDLRKRNRLLAEGTVTHRYGHCWRCKTPIIYLAT 409
Query: 417 DQWFLKISKVKDKIIKENDEKVTWYPDWV-KIRFDNGVRDSGDWVISRQRYWGIPLPIWQ 475
+QWFLK++ +KDK+++ D V WYP+W RF V + DW ISRQRYWG+P+P+W+
Sbjct: 410 EQWFLKVTDIKDKMLEAIDA-VDWYPEWAGSARFRTWVEGARDWCISRQRYWGMPIPVWK 468
Query: 476 SED-GEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAF 534
+ G++ V+G+ EL+E + A G +EL HRPYVD
Sbjct: 469 CKKCGKLEVIGTKAELLEKSGA----GSDVEL--------------------HRPYVDKL 504
Query: 535 IIKVN-GKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWF 593
I G + +RV+DV DVWFDS +ASWA+L +P+ +E F++ WPADFI EG DQ WF
Sbjct: 505 TIPCECGGEKKRVEDVFDVWFDSAVASWATLKFPQTREQFDEWWPADFITEGHDQTRGWF 564
Query: 594 YSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYML 653
YSQ AS+V F PY+ V MHG+ LD G KMSKSLGN++ P +V+++ G DT R Y+L
Sbjct: 565 YSQLGASMVGFGRAPYKSVLMHGFTLDAGGKKMSKSLGNVVSPIDVIDKYGADTLRAYVL 624
Query: 654 WATNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDEL--PFREED 711
++ PW++LKF+ + VE V R +NILWNV+ YM+LDNFDP K++ D + REED
Sbjct: 625 SSSAPWDDLKFNQEEVENVHRSINILWNVFRFPLPYMALDNFDPLKVSLDSVKDALREED 684
Query: 712 KWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKL 771
+WILSR+ S++ V+ + ++L KA R + F +EDLSRWY++LIR R W E +DPDKL
Sbjct: 685 RWILSRIQSVVKAVDEAMSGYFLHKAVREILEFTLEDLSRWYIQLIRPRTWTEADDPDKL 744
Query: 772 AAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPF--TNVESVHMLDWPKVDEKAIDEE 829
AAY L++V+ L +L++PF PY+AEE+YQNLIR +ESVHM DWPKV+E +D E
Sbjct: 745 AAYRVLYEVYVTLTKLISPFMPYLAEEMYQNLIRNVDPNALESVHMCDWPKVNEAYLDPE 804
Query: 830 LEREMEFIRRIVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQLNAK 889
LE M R IVEA S ARQ+A KLR+PV RI++ E E KAVERL +L DQ N+K
Sbjct: 805 LEAAMSTARSIVEAASNARQKAGRKLRWPVSRIVVSPESEDAAKAVERLRSVLMDQTNSK 864
Query: 890 EVKVGRV-----ERELTIKPNFAKLGPEFKGDA-KIIAKWINENG----RELYEKGELTV 939
+ + V E L + P+ +K+GP FK DA K+I +G + E GE +
Sbjct: 865 AIVLTPVGESWDELGLEVIPDPSKIGPVFKKDAGKVIPALQKVDGFALKKAFAEAGEFEL 924
Query: 940 EI-DGKTFHLTREHIIVEEKLPDFFVSEEFEGGRVFVDKTLTRELIAEGLAREFVRRIQE 998
+ D T +T +E LP+ S E + G V+VD LT EL AEG ARE +RR+Q+
Sbjct: 925 SLADRTTVTVTPGMANFKETLPEGTASAESDAGLVYVDANLTPELEAEGYAREVIRRLQD 984
Query: 999 MRKRLDLDVNDRIIVTIETTDENVELLKENL-DYIMRETRADKIVFGK----AKGYVVEW 1053
MRK LDL V++ I V++ DE V L E L D I E RA+ + G + V +W
Sbjct: 985 MRKELDLVVDENIRVSVRIEDERVLRLVETLKDLIAEEVRAEILNLGSDIDVSGALVKDW 1044
Query: 1054 --PEVQAKIGIEK 1064
+ K+GI K
Sbjct: 1045 DVEGIAMKMGISK 1057
>sp|Q9YF67|SYI_AERPE ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|7437559|pir||E72729 probable isoleucyl-tRNA
synthetase APE0374 - Aeropyrum pernix (strain K1)
>gi|5104013|dbj|BAA79329.1| (AP000059) 1064aa long
hypothetical isoleucyl-tRNA synthetase [Aeropyrum pernix]
Length = 1064
Score = 987 bits (2523), Expect = 0.0
Identities = 521/1063 (49%), Positives = 699/1063 (65%), Gaps = 59/1063 (5%)
Query: 6 EFREYDPKKLEEKVEKFWSENEIYRKVKELRKDGP-KYYFLDGPPYVSG-AIHLGTAWNK 63
E YD LE V+ +W EN IYRKVKE P K+YFLDGPPY S +IH+GTAWNK
Sbjct: 9 EGERYDQFALESFVKSYWEENSIYRKVKEKSSRAPRKFYFLDGPPYASAKSIHIGTAWNK 68
Query: 64 IIKDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCK 123
++KD+++RF M GYNVW +PGYD HGLPIEVK+EQ+LG++ K+EIEEK+GVENFI CK
Sbjct: 69 VVKDVVLRFYRMTGYNVWDKPGYDTHGLPIEVKIEQSLGVRVKREIEEKVGVENFIAACK 128
Query: 124 EFALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHW 183
F N++ MT QFK +G++MDW+NPY+T ++EYIES W+ +K+AWEKGLL K RVLHW
Sbjct: 129 RFVDENMEAMTRQFKEIGVFMDWENPYVTYRDEYIESGWWLVKKAWEKGLLYKGYRVLHW 188
Query: 184 CPRCETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPD 243
CPRCET LA++EV EY+ +DPSIYVKFPVEG+E EYLL+WTTTPWTLPAN V AHPD
Sbjct: 189 CPRCETTLADYEV-SEYRELEDPSIYVKFPVEGREGEYLLVWTTTPWTLPANAFVMAHPD 247
Query: 244 YDYVKVKVEFNGREEYWILAKALVDKVLGEIGV-KGEVVEEFKGRELEGLRYVHILMDEY 302
+YVKV+V GR+ ILAKA +D V+ E GV + EV+E KG +LEGLRY H L D
Sbjct: 248 MEYVKVRV---GRDTL-ILAKARLDHVMREAGVSEYEVLEVLKGSQLEGLRYRHPLEDVV 303
Query: 303 PRQKEFKEKYEWAHRVILA-DFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQ 361
Q+E +W H+V++A + VT EG+GLVH+APGHG D+E+ Q+ G PV S +D++
Sbjct: 304 DAQRELS---KW-HKVVMAPEAVTPHEGSGLVHSAPGHGTIDYEIAQRIGAPVVSLVDER 359
Query: 362 GKYTE--GKWKGIYVK-EADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQ 418
G TE GK+ G+Y + EA+ I+E LR +G L A I H+YP CWRCKTPL+ RAT Q
Sbjct: 360 GFMTEAAGKYSGLYFRGEANKAIVEDLRARGALFHAATIVHRYPVCWRCKTPLLLRATTQ 419
Query: 419 WFLKISKVKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQ-SE 477
WF+ ++++K+++++E EKV W P W K RF N +R+ DWVISRQRYWGIPLP+W+ S
Sbjct: 420 WFVAVTRLKNQLMRE-AEKVEWQPGWAKTRFMNMLRELRDWVISRQRYWGIPLPVWRCSS 478
Query: 478 DGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIK 537
G +VVGS EL + G R PE+LHRP+VD +K
Sbjct: 479 CGYEHVVGSVEELESM------GGRR-------------------PENLHRPWVDRVELK 513
Query: 538 VN--GKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYS 595
G M+RV DV+DVWFDSGIA +ASLGYPR++E +E+L P DFIVEG DQ+ WF+S
Sbjct: 514 CPRCGGSMKRVPDVLDVWFDSGIAFYASLGYPRDRETWERLKPVDFIVEGHDQIRGWFFS 573
Query: 596 QQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWA 655
+ ++ F PYRRV +HG+ LDE+G +M KSLGN + EE++ + RD RF++L
Sbjct: 574 LLRSGVIGFGETPYRRVLVHGFALDEQGREMHKSLGNYVDFEELIAKVPRDVVRFWVLQN 633
Query: 656 TNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRK--LNPDELPFREEDKW 713
T WE+L+FSWKG++ +RR N++WNVY AS YM LD FDPR+ L+ E ED+W
Sbjct: 634 T-VWEDLRFSWKGLDLMRRDFNVIWNVYAFASIYMGLDRFDPRRTSLSSVEDSLEVEDRW 692
Query: 714 ILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAA 773
ILSR+ SL +E + A RAL +F++ED+S WY+R+IR+R+W E + P K AA
Sbjct: 693 ILSRLASLKRRYLTAMEDLRIHDAARALRSFIIEDVSHWYLRIIRRRVWEEVDTPSKRAA 752
Query: 774 YYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTN--VESVHMLDWPKVDEKAIDEELE 831
Y TL+KV L + AP PY AE +Y + R ES+HMLD P+ ++ ID LE
Sbjct: 753 YATLYKVLWEWLLMAAPLIPYTAEYLYIKVFREAEERPEESIHMLDMPEPEDHLIDSTLE 812
Query: 832 REMEFIRRIVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQLNAKEV 891
+ME R ++EA +AR A +KLR PVRR+II + V+ ++ RL ++R NAKE+
Sbjct: 813 EDMEKARMVLEAILSARNEAGLKLRRPVRRVIIAASNPGVEGSLRRLEGLIRLMANAKEI 872
Query: 892 KVG-----RVERELTIKPNFAKLGPEFKGDAKIIAKWINEN----GRELYEKGELTVEID 942
+ R ++P++ +LGP++K D + + I E GR L EKG E +
Sbjct: 873 EFAPASALEATRIYRVEPDYGRLGPKYKRDMPKVLRLIEEKGGEIGRVLAEKGVYEGEYE 932
Query: 943 GKTFHLTREHIIVEEKLPDFFVSEEFEGGRVFVDKTLTRELIAEGLAREFVRRIQEMRKR 1002
G LT E + ++ + P++ + G V VD LT+E + EGLAR+ VRRIQ MRK
Sbjct: 933 GLPVKLTLEDVSLKAEYPEWLKVRDTPLGLVAVDTRLTKEEVLEGLARDIVRRIQAMRKE 992
Query: 1003 LDLDVNDRIIVTIETTDENVELLKENLDYIMRETRADKIVFGK 1045
V D + V I+ ++ VE + +YI RETRA K+ G+
Sbjct: 993 AGYSVEDYVEVWIQGGEDVVEAVNALKEYIKRETRALKLEVGE 1035
>gb|AAK41020.1| Isoleucine-tRNA synthetase (ileS) [Sulfolobus solfataricus]
Length = 986
Score = 831 bits (2124), Expect = 0.0
Identities = 441/1022 (43%), Positives = 643/1022 (62%), Gaps = 59/1022 (5%)
Query: 64 IIKDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCK 123
+IKD I+R++ + G V QPGYD HGLPIEV E+ LG+ K+EI +KIGVE FI KCK
Sbjct: 1 MIKDCILRYQRVLGKRVHDQPGYDTHGLPIEVATEKLLGISNKQEIIDKIGVETFINKCK 60
Query: 124 EFALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHW 183
EFAL+N MT+ FK +G++MDW+ PY T+ YI S+W +K+A+EKG+L+K VLHW
Sbjct: 61 EFALSNADKMTQNFKNVGVFMDWERPYYTLDPSYISSSWSVIKKAYEKGMLDKGTAVLHW 120
Query: 184 CPRCETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPD 243
CPRCET L+++EV EY+ +DPSIYVKF ++G++N YLLIWTTTPWT+P+N+ V + D
Sbjct: 121 CPRCETTLSDYEV-SEYRDLEDPSIYVKFKIKGEKNRYLLIWTTTPWTIPSNVFVMINKD 179
Query: 244 YDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKG-EVVEEFKGRELEGLRYVHILMDEY 302
YDY V+V NG E ++AK V+ V+ E + +++ +KG EL G++Y H L +
Sbjct: 180 YDYADVEV--NG--EILVIAKDRVEAVMKEASITNYKILRTYKGSELIGIKYEHPLREFV 235
Query: 303 PRQKEFKEKYEWAHRVILA-DFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQ 361
Q K + H+V+ A + VTL +GTGLVH+A GHGEEDF VGQKYG PV ++D+
Sbjct: 236 SAQ----TKLDDFHQVVDAGNIVTLTDGTGLVHSATGHGEEDFTVGQKYGFPVVMFVNDR 291
Query: 362 GKYTE--GKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQW 419
G++TE GK+KG+ V++A II L+ K L G+I H+YP CWRCKTPLI RA DQW
Sbjct: 292 GEFTEEGGKYKGLKVRDASKAIISDLKSKNTLFFEGKIVHRYPVCWRCKTPLILRAIDQW 351
Query: 420 FLKISKVKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSED- 478
F++++K+KDK++ E EKV W PDW K R N V++ DWVISRQR+WG PLPIW E
Sbjct: 352 FIRVTKIKDKMLNE-IEKVNWIPDWGKSRISNMVKELRDWVISRQRFWGTPLPIWICERC 410
Query: 479 GEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKV 538
+ VVGS EL +A+ P DLHRP++D +K
Sbjct: 411 NNVMVVGSKEELESIAI------------------------DPVPNDLHRPWIDNVRVKC 446
Query: 539 N--GKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQ 596
N G +R+ DV DVWFDSG+A +ASLG +E +++L P D ++EG DQ+ WF+S
Sbjct: 447 NKCGGVAKRIPDVADVWFDSGVAFFASLGKDW-QEKWKELGPVDLVLEGHDQLRGWFFSL 505
Query: 597 QAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWAT 656
+ ++ D PY V +HG++LDE+G +M KSLGN + P VVE+ GRD R ++L T
Sbjct: 506 LRSGLILLDRAPYTSVLVHGFMLDEQGREMHKSLGNYVEPSVVVEKYGRDILRLWLLRNT 565
Query: 657 NPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDEL--PFREEDKWI 714
WE+ KFSWK +E +R L I+WN +V AS YM+LDNF+P K D++ + ED WI
Sbjct: 566 T-WEDAKFSWKALELTKRDLQIIWNTFVFASMYMNLDNFEPDKYTLDDIIKYAKIEDLWI 624
Query: 715 LSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAY 774
LSR NS++ +V ++ + + + T L NF++ED+SR+Y+RLIRKR W+E DK+A Y
Sbjct: 625 LSRFNSMLKKVNESMKDYKVHEMTNYLINFLIEDVSRFYIRLIRKRAWIEANTQDKIAMY 684
Query: 775 YTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREM 834
Y L+ + + L + P+I+E+IY++ + ESV M DE+ ID ELER
Sbjct: 685 YILYYILKQWIILASTIIPFISEKIYKSFV--VNAKESVSMESSINYDERFIDNELERAF 742
Query: 835 EFIRRIVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQLNAKEVKVG 894
E R I EA AR +A IKLR+P+ ++ I E+E V R+ +L LNAK++++
Sbjct: 743 EVAREINEASLNARAKAGIKLRWPLAKVYIFIENEDTLAKVGRIKDVLISMLNAKDIEIS 802
Query: 895 RVE-----RELTIKPNFAKLGPEFKGDAKIIAKWINEN----GRELYEKGELTVEIDGKT 945
++E + ++PN + +G E+K + I ++I N ++ K + +ID
Sbjct: 803 KIEGFKSFSKYKVEPNRSIIGKEYKSMSPKIVEYIENNRDIIAMDILNKKQHVAKIDNFD 862
Query: 946 FHLTREHIIVEEKLPDFFVSEEFEGGRVFVDKTLTRELIAEGLAREFVRRIQEMRKRLDL 1005
L ++I+ E+ + F+S +F G V + K ++ EGL R+ +RRIQ MRK+L L
Sbjct: 863 IILNASYVIISEETVEGFISSKFSKGIVVISKEISESEEEEGLIRDIIRRIQFMRKQLKL 922
Query: 1006 DVNDRIIVTIETTDENVELLKENLDYIMRETRADKIVFGKAKGYVVEWPEVQAK---IGI 1062
+V D I ++++ +E V+ +++ ++I ETRA I+ G+AKG + +++ + IGI
Sbjct: 923 NVLDYIEISMKVPEERVKTIQKWEEFIKSETRASNIILGEAKGDITMDWDIEGESYIIGI 982
Query: 1063 EK 1064
+K
Sbjct: 983 KK 984
>emb|CAB57581.1| (Y18930) isoleucyl-tRNA synthetase [Sulfolobus solfataricus]
Length = 986
Score = 831 bits (2124), Expect = 0.0
Identities = 441/1022 (43%), Positives = 643/1022 (62%), Gaps = 59/1022 (5%)
Query: 64 IIKDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCK 123
+IKD I+R++ + G V QPGYD HGLPIEV E+ LG+ K+EI +KIGVE FI KCK
Sbjct: 1 MIKDCILRYQRVLGKRVHDQPGYDTHGLPIEVATEKLLGISNKQEIIDKIGVETFINKCK 60
Query: 124 EFALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHW 183
EFAL+N MT+ FK +G++MDW+ PY T+ YI S+W +K+A+EKG+L+K VLHW
Sbjct: 61 EFALSNADKMTQNFKNVGVFMDWERPYYTLDPSYISSSWSVIKKAYEKGMLDKGTAVLHW 120
Query: 184 CPRCETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPD 243
CPRCET L+++EV EY+ +DPSIYVKF ++G++N YLLIWTTTPWT+P+N+ V + D
Sbjct: 121 CPRCETTLSDYEV-SEYRDLEDPSIYVKFKIKGEKNRYLLIWTTTPWTIPSNVFVMINKD 179
Query: 244 YDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKG-EVVEEFKGRELEGLRYVHILMDEY 302
YDY V+V NG E ++AK V+ V+ E + +++ +KG EL G++Y H L +
Sbjct: 180 YDYADVEV--NG--EILVIAKDRVEAVMKEASITNYKILRTYKGSELIGIKYEHPLREFV 235
Query: 303 PRQKEFKEKYEWAHRVILA-DFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQ 361
Q K + H+V+ A + VTL +GTGLVH+A GHGEEDF VGQKYG PV ++D+
Sbjct: 236 SAQ----TKLDDFHQVVDAGNIVTLTDGTGLVHSATGHGEEDFTVGQKYGFPVVMFVNDR 291
Query: 362 GKYTE--GKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQW 419
G++TE GK+KG+ V++A II L+ K L G+I H+YP CWRCKTPLI RA DQW
Sbjct: 292 GEFTEEGGKYKGLKVRDASKAIISDLKSKNTLFFEGKIVHRYPVCWRCKTPLILRAIDQW 351
Query: 420 FLKISKVKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSED- 478
F++++K+KDK++ E EKV W PDW K R N V++ DWVISRQR+WG PLPIW E
Sbjct: 352 FIRVTKIKDKMLNE-IEKVNWIPDWGKSRISNMVKELRDWVISRQRFWGTPLPIWICERC 410
Query: 479 GEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKV 538
+ VVGS EL +A+ P DLHRP++D +K
Sbjct: 411 NNVMVVGSKEELESIAI------------------------DPVPNDLHRPWIDNVRVKC 446
Query: 539 N--GKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQ 596
N G +R+ DV DVWFDSG+A +ASLG +E +++L P D ++EG DQ+ WF+S
Sbjct: 447 NKCGGVAKRIPDVADVWFDSGVAFFASLGKDW-QEKWKELGPVDLVLEGHDQLRGWFFSL 505
Query: 597 QAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWAT 656
+ ++ D PY V +HG++LDE+G +M KSLGN + P VVE+ GRD R ++L T
Sbjct: 506 LRSGLILLDRAPYTSVLVHGFMLDEQGREMHKSLGNYVEPSVVVEKYGRDILRLWLLRNT 565
Query: 657 NPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDEL--PFREEDKWI 714
WE+ KFSWK +E +R L I+WN +V AS YM+LDNF+P K D++ + ED WI
Sbjct: 566 T-WEDAKFSWKALELTKRDLQIIWNTFVFASMYMNLDNFEPDKYTLDDIIKYAKIEDLWI 624
Query: 715 LSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAY 774
LSR NS++ +V ++ + + + T L NF++ED+SR+Y+RLIRKR W+E DK+A Y
Sbjct: 625 LSRFNSMLKKVNESMKDYKVHEMTNYLINFLIEDVSRFYIRLIRKRAWIEANTQDKIAMY 684
Query: 775 YTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREM 834
Y L+ + + L + P+I+E+IY++ + ESV M DE+ ID ELER
Sbjct: 685 YILYYILKQWIILASTIIPFISEKIYKSFV--VNAKESVSMESSINYDERFIDNELERAF 742
Query: 835 EFIRRIVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQLNAKEVKVG 894
E R I EA AR +A IKLR+P+ ++ I E+E V R+ +L LNAK++++
Sbjct: 743 EVAREINEASLNARAKAGIKLRWPLAKVYIFIENEDTLAKVGRIKDVLISMLNAKDIEIS 802
Query: 895 RVE-----RELTIKPNFAKLGPEFKGDAKIIAKWINEN----GRELYEKGELTVEIDGKT 945
++E + ++PN + +G E+K + I ++I N ++ K + +ID
Sbjct: 803 KIEGFKSFSKYKVEPNRSIIGKEYKSMSPKIVEYIENNRDIIAMDILNKKQHVAKIDNFD 862
Query: 946 FHLTREHIIVEEKLPDFFVSEEFEGGRVFVDKTLTRELIAEGLAREFVRRIQEMRKRLDL 1005
L ++I+ E+ + F+S +F G V + K ++ EGL R+ +RRIQ MRK+L L
Sbjct: 863 IILNASYVIISEETVEGFISSKFSKGIVVISKEISESEEEEGLIRDIIRRIQFMRKQLKL 922
Query: 1006 DVNDRIIVTIETTDENVELLKENLDYIMRETRADKIVFGKAKGYVVEWPEVQAK---IGI 1062
+V D I ++++ +E V+ +++ ++I ETRA I+ G+AKG + +++ + IGI
Sbjct: 923 NVLDYIEISMKVPEERVKTIQKWEEFIKSETRASNIILGEAKGDITMDWDIEGESYIIGI 982
Query: 1063 EK 1064
+K
Sbjct: 983 KK 984
>gb|AAG20324.1| (AE005106) isoleucyl-tRNA synthetase; IleS [Halobacterium sp. NRC-1]
Length = 1070
Score = 764 bits (1951), Expect = 0.0
Identities = 427/1095 (38%), Positives = 627/1095 (56%), Gaps = 73/1095 (6%)
Query: 9 EYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDM 68
+YDP +EE+V +W + Y + + R D ++F+DGPPY SGA H+GT WNK +KD
Sbjct: 10 QYDPAGVEERVFSYWEAVDAYEQTVDHRADAETFFFVDGPPYTSGAAHMGTTWNKTLKDA 69
Query: 69 IIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALN 128
IR+ MQGY+V +PGYDMHGLPIE KVE+ LG ++KK+I+E G E FI++CK FA +
Sbjct: 70 YIRYHRMQGYDVTDRPGYDMHGLPIETKVEEQLGFESKKDIQE-FGEEAFIEECKRFADD 128
Query: 129 NLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCE 188
NL + F+ G+WMDWDNPY T+ Y+E+AW+ + GL+E+ +R + CPRCE
Sbjct: 129 NLDGLQSDFQSFGVWMDWDNPYKTVDPSYMEAAWWAFSEVHDNGLVERGQRSISQCPRCE 188
Query: 189 TALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVK 248
TA+A +EV EY+ DPSIYV+F ++ +E L++WTTTPWT+PAN V+ D DY +
Sbjct: 189 TAIANNEV--EYEDVTDPSIYVRFDLDDREGS-LVVWTTTPWTIPANQFVAVDEDGDYQQ 245
Query: 249 VKVEF-NGREEYWILAKALVDKVLGEIGVKG-EVVEEFKGRELEGLRYVHILMDEYPRQK 306
V+ +G + +A V+ VL G E+V + G +L G Y L D P
Sbjct: 246 VRATTPDGETDVLYVASECVEDVLSAGGYSDHEIVADHSGSDLIGWSYTPPLADAVPANP 305
Query: 307 EFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTE 366
+ H V D+V + TGLVH+APGHGEEDFE G + LPV+ P+ + G YT+
Sbjct: 306 T---DADGTHEVYHGDWVEADR-TGLVHSAPGHGEEDFERGAELDLPVFCPVGEDGVYTD 361
Query: 367 --GKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKIS 424
GK+ G +V++A+ II L + ++ + +EH Y HCWRC T +I TDQWF+ I+
Sbjct: 362 AGGKYAGAFVRDANDDIIADLEARDAMLASQTVEHSYGHCWRCDTGIIQIVTDQWFITIT 421
Query: 425 KVKDKIIKENDEKVTWYPDWVKI-RFDNGVRDSGDWVISRQRYWGIPLPIWQSEDG---- 479
VKD+++ D W+P+W + RF + V ++ DW +SRQRYWGIP+PIW ED
Sbjct: 422 DVKDELLANMDTS-EWHPEWARDNRFRDFVENAPDWNVSRQRYWGIPVPIWTPEDWSGDA 480
Query: 480 -EIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPE--DLHRPYVDAFII 536
++ VVG+ EL LA ++ + P DLH+P VD I
Sbjct: 481 EDVLVVGTREELAALA-----------------------DQDVDPASVDLHKPTVDDITI 517
Query: 537 KVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQ 596
+G + RV DV DVW DS +ASW +L YP ++ F++LWPAD I+E DQ WF+SQ
Sbjct: 518 TEDGTEYTRVPDVFDVWLDSSVASWGTLNYPEQEDDFDELWPADLIMEAHDQTRGWFWSQ 577
Query: 597 QAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWAT 656
A VPY V MHGY G MSKS G I P EV++ G D R ++L T
Sbjct: 578 LGMGTAALGDVPYEEVLMHGYANMPDGRGMSKSKGITIEPNEVIDEYGADPMRMFLLSVT 637
Query: 657 NPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFD---PRKLNPD-------ELP 706
+++ FSW E ++R LNILWNV+ YM+LD+FD P D +
Sbjct: 638 PQGDDMSFSWDETENMQRDLNILWNVFRFPRPYMALDDFDANVPAAFGGDDAGVGIADAD 697
Query: 707 FREEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGE 766
D+W+LSR+ + ++ E F +A A+ FVVEDLSR+YV+++R+R+W +
Sbjct: 698 LETVDEWLLSRLQHVKADATAHWEDFEQHRALDAVLEFVVEDLSRYYVQVVRERMWEDDA 757
Query: 767 DPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAI 826
K AAY T+ +V ++ LLAP+ P++ EE+Y +L ++VHM DWP V+E
Sbjct: 758 SASKTAAYATMQRVLLEVVALLAPYAPFVTEELYSHLTGD-RGYDTVHMADWPTVEESLR 816
Query: 827 DEELEREMEFIRRIVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQL 886
LE ++ +R EAGS ARQ+A KLR+PV R++++ +++V A++ +L D+L
Sbjct: 817 APALEADVAVLRAAEEAGSHARQQAGRKLRWPVTRVVVDAAEDSVVDALDAHGDLLADRL 876
Query: 887 NAKEVKV---GRVEREL--TIKPNFAKLGPEFKGDAKIIAKWINE---NGRELYEKGE-L 937
N + ++V G EL + + + ++LGP F DA + +N+ R++ E +
Sbjct: 877 NTRAIEVVEPGAAWDELAYSARADMSELGPAFGDDAGAVMNALNDARVTDRDIDALAEQV 936
Query: 938 TVEIDGKTFHLTREHIIVEEKLPDFFVSEEFE----GGRVFVDKTLTRELIAEGLAREFV 993
++ LT E + E+ P+ FE G V+VD L ++ +EG ARE V
Sbjct: 937 AADLGRDDIELTTEMVEFVEETPEHVAGAAFETETAAGTVYVDTELNEDVESEGYAREVV 996
Query: 994 RRIQEMRKRLDLDVNDRIIVTIETTDENV-ELLKENLDYIMRETRADKIVFGKAK-GYVV 1051
RR+QEMRK +DL ++ I + + DE V EL+ + I ETRA ++ G+ + G+
Sbjct: 997 RRVQEMRKEMDLAMDAEIRLDVLVFDERVGELVARHEPLITAETRAREL--GEVEDGHRE 1054
Query: 1052 EWPEVQAKIGIEKVE 1066
EW +V+ I +VE
Sbjct: 1055 EW-DVEGTTMILEVE 1068
>pir||T34946 probable isoleucyl-tRNA synthetase - Streptomyces coelicolor
>gi|5689948|emb|CAB51985.1| (AL109663) putative
isoleucyl-tRNA synthetase [Streptomyces coelicolor A3(2)]
Length = 1047
Score = 652 bits (1663), Expect = 0.0
Identities = 391/1072 (36%), Positives = 578/1072 (53%), Gaps = 80/1072 (7%)
Query: 5 PEFREY----DPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTA 60
P++R+ D LE V FW E +I+ K E + P++ F +GPP +G
Sbjct: 4 PQYRQVPAQVDLPALEHAVLDFWREQKIFAKSLEQSEGRPEWVFYEGPPTANGMPGAHHI 63
Query: 61 WNKIIKDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIK 120
++ KD+ RFRTM+GY+V R+ G+D HGLP+E+ VE+ LG K++IE G+ F
Sbjct: 64 EARVFKDVFPRFRTMRGYHVGRKAGWDCHGLPVELAVEKELGFSGKQDIEA-YGIAEFNA 122
Query: 121 KCKEFALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRV 180
KC+E + E +G W D +PY T+ EYIES W++LK + KGLL +D RV
Sbjct: 123 KCRESVTRHTDAFEELTTRMGYWADLQDPYRTMDPEYIESVWWSLKEIFNKGLLVQDHRV 182
Query: 181 LHWCPRCETALAEHEVRGEYKLRKDPSIYVKFPVEG---KENEYLLIWTTTPWTLPANLA 237
WCPRC T L++HE+ Y+ DPS+YV+FP+ L++WTTTPWTL +N A
Sbjct: 183 APWCPRCGTGLSDHELAQGYETVVDPSVYVRFPLTSGPLAGEAALVVWTTTPWTLVSNTA 242
Query: 238 VSAHPDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHI 297
V+AHPD YV V +G EE ++A+ L+ K LGE G E G +
Sbjct: 243 VAAHPDVTYV---VATDG-EEKLVVAEPLLAKALGE------------GWETTGQSFTGA 286
Query: 298 LMDEYPRQKEFK--EKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVY 355
M+ + Q+ F+ E E AH V+ AD+VT E+GTGLVH +P GE+D +V + YGLPV
Sbjct: 287 EMERWTYQRPFELVEFPEPAHYVVNADYVTTEDGTGLVHQSPAFGEDDLKVCRAYGLPVV 346
Query: 356 SPLDDQGKYTEG--KWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIF 413
+P+ G + E G++ K+AD K+ E L +G L K EH YPHCWRC T L++
Sbjct: 347 NPVRPDGTFEEDVPLVGGVFFKKADEKLTEDLETRGLLFKHIPYEHSYPHCWRCHTALLY 406
Query: 414 RATDQWFLKISKVKDKIIKENDEKVTWYPDWVKI-RFDNGVRDSGDWVISRQRYWGIPLP 472
A W+++ + +KD++++EN EK W+PD VK R+ + + ++ DW +SR RYWG PLP
Sbjct: 407 YAQPSWYIRTTAIKDRLLQEN-EKTNWFPDAVKHGRYGDWLNNNIDWALSRNRYWGTPLP 465
Query: 473 IWQSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVD 532
IW+ + + VVGS EL EL+ + L P HRP++D
Sbjct: 466 IWRCAEDHLTVVGSRAELTELS--------------------GTDQSSLDP---HRPFID 502
Query: 533 --AFIIKVNGKDMR--RVKDVVDVWFDSGIASWASLGYP-RNKELFEKLWPADFIVEGED 587
F G + RV +V+D W+DSG +A GYP +NKELFE +PA FI E D
Sbjct: 503 DVTFTCAQEGCSLEAVRVPEVIDAWYDSGSMPFAQWGYPYKNKELFESRYPAQFISEAID 562
Query: 588 QVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDT 647
Q WFY+ A + FD Y V G++L E G KMSK LGNI++P ++++ G D
Sbjct: 563 QTRGWFYTLMAVGTLVFDKSSYENVVCLGHILAEDGRKMSKHLGNILQPIPLMDQHGADA 622
Query: 648 FRFYMLWATNPWENLKFSWKGVEQ-VRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELP 706
R++M +PW + +++ VR+ L WN + Y + P + +P
Sbjct: 623 VRWFMAAGGSPWAARRVGHGTIQEVVRKTLLTYWNTVAFQALYARTTGWAPSEADPAPAD 682
Query: 707 FREEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGE 766
D+W+LS +++L +V ++++ +A + L F V+DLS WYVR R+R W +G+
Sbjct: 683 RPVLDRWLLSELHALTDQVTQALDAYDTQRAGKLLSAF-VDDLSNWYVRRSRRRFW-QGD 740
Query: 767 DPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFT--NVESVHMLDWPKVDEK 824
AA TL +V + + +L+AP TP+I E ++Q+L+ P T ESVH+ WP+ D
Sbjct: 741 K----AALRTLHEVVETVTKLMAPLTPFITERVWQDLVVPVTPGAPESVHLSSWPEADLT 796
Query: 825 AIDEELEREMEFIRRIVEAGSAARQRAKIKLRYPVRRIIIETED-ETVKKAVERLNRILR 883
AID EL ++M +RR+VE G A R + +K R P+ R +I +T+ L+ +
Sbjct: 797 AIDPELSKQMVLVRRLVELGRATRAESGVKTRQPLSRALIAVAGFDTLS---PELHSQIT 853
Query: 884 DQLNAKEV----KVGRVERELTIKPNFAKLGPEFKGDAKIIAKWINENGRE----LYEKG 935
++LN + +VG + T K NF LG F + +AK + +G
Sbjct: 854 EELNVASLASLSEVGGSLVDTTAKANFRALGKRFGKRVQDVAKAVAAADAAALSLALREG 913
Query: 936 ELTVEIDGKTFHLTREHIIVEEKLPDFFVSEEFEGGRVFVDKTLTRELIAEGLAREFVRR 995
+VE+DG+T L + +I+ E + + G V +D LT EL GLAR+ +R
Sbjct: 914 TASVEVDGETVTLAPDEVIITETPREGWSVASDSGATVALDLELTEELRRAGLARDAIRL 973
Query: 996 IQEMRKRLDLDVNDRIIVTIETTD-ENVELLKENLDYIMRETRADKIVFGKA 1046
IQE RK LDV DRI + TD + L ++ I E A G+A
Sbjct: 974 IQEARKNSGLDVADRIALRWTATDPATIAALTDHSGLISDEVLATDFAQGEA 1025
>sp|O51773|SYI_BORBU ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|7437557|pir||H70203 isoleucine--tRNA ligase (EC
6.1.1.5) ileS - Lyme disease spirochete
>gi|2688775|gb|AAC67179.1| (AE001181) isoleucyl-tRNA
synthetase (ileS) [Borrelia burgdorferi]
Length = 1042
Score = 641 bits (1635), Expect = 0.0
Identities = 382/1064 (35%), Positives = 591/1064 (54%), Gaps = 59/1064 (5%)
Query: 1 MIKEPEFREYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTA 60
M K+ E + PK +EEK+ KFW++N+I+ K + R+ ++ F DGPP+ +G H G
Sbjct: 1 MFKKVENKANFPK-IEEKILKFWNDNKIFEKSIKQREGCEEFTFYDGPPFATGLPHFGHF 59
Query: 61 WNKIIKDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIK 120
IKD+I R++TMQG V R G+D HGLP+E +VE+ LG+ K EI E G+ENF K
Sbjct: 60 VPNTIKDIIPRYQTMQGKYVKRNFGWDTHGLPVEYEVEKKLGISGKYEI-ENYGIENFNK 118
Query: 121 KCKEFALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRV 180
+C++ L + LG W+D++ Y T+ ++ES W+ K +EKGL+ + V
Sbjct: 119 ECRKIVLRYTEEWKNIILRLGRWVDFEKGYKTMDISFMESVWWVFKNLYEKGLIYESYYV 178
Query: 181 LHWCPRCETALAEHEVR-GEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVS 239
L + P+ T L+ EV GEYK DPS+ +KF ++ K NEYLL+WTTTPWTLP+NL ++
Sbjct: 179 LPYSPKLATPLSNFEVNLGEYKEVNDPSLTIKFKIKDK-NEYLLVWTTTPWTLPSNLGIA 237
Query: 240 AHPDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILM 299
+ +Y K+ + +EE IL ++ + ++E+FKG +LEG+ Y I
Sbjct: 238 VGQEIEYSKIFDK--TKEEILILGSKKLNSYYDDEN-SYTIIEKFKGSKLEGIEYEPIF- 293
Query: 300 DEYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKY-GLPVYSPL 358
++K + A +V AD+VT ++GTG+VH AP GEED+ + +K+ + + PL
Sbjct: 294 -----NYFLEQKDKGAFKVHTADYVTTDDGTGIVHIAP-FGEEDYRILKKHTNVDIIDPL 347
Query: 359 DDQGKYTE--GKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRAT 416
D + K+T +KG++VK+AD KIIE+L+ + +L K H+YP C+R P+I+R
Sbjct: 348 DAECKFTNQVKDFKGLFVKDADKKIIENLKLRNFLFKRENYLHRYPFCYRTNCPIIYRPI 407
Query: 417 DQWFLKISKVKDKIIKENDEKVTWYPDWVKI-RFDNGVRDSGDWVISRQRYWGIPLPIW- 474
WF+ + K+K K+++ N EK+ W P +K RF + ++ DW ISR R+WG P+PIW
Sbjct: 408 SSWFVNVEKIKTKLLEVN-EKINWMPAHLKKGRFGKWLENAKDWAISRNRFWGNPIPIWI 466
Query: 475 QSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAF 534
S+ G+ +GS +EL L +G++I EDLH+ +D
Sbjct: 467 CSKTGKKICIGSKKELENL------SGQKI-------------------EDLHKDQIDKI 501
Query: 535 I-IKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKEL-FEKLWPADFIVEGEDQVTKW 592
+G R +V+D WF+SG +AS YP E+ F+ ++PADFI EG DQ W
Sbjct: 502 TWPSKDGGKFIRTSEVLDCWFESGAMPYASNHYPFTNEINFKNIFPADFIAEGLDQTRGW 561
Query: 593 FYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYM 652
FY+ F+ ++ V ++G VL G KMSKS N P +V+ G D R Y+
Sbjct: 562 FYTLTILGTALFENTAFKNVIVNGLVLSSDGRKMSKSFKNYTDPMQVINTFGADALRLYL 621
Query: 653 LWA-TNPWENLKFSWKGVEQVRRMLNI-LWNVYVLASTYMSLDNFDPRKLNPDELPFREE 710
+ + ++LK+S GV V + + I +WN Y +TY +D F P K N
Sbjct: 622 IMSPVVKADDLKYSDNGVRDVLKNIIIPIWNAYSFFTTYAIIDKFKPPK-NLSLAKNNNL 680
Query: 711 DKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDK 770
DKWI+S + SL + I+ + LTK+ +L F ++ L+ WY+R R+R W D DK
Sbjct: 681 DKWIISELESLKKILNTEIDKYNLTKSIESLLEF-IDKLNNWYIRRSRRRFWKSENDKDK 739
Query: 771 LAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEEL 830
AY TL+ L+ LLAPF P+I EEIYQNL + + +S+H+ D+PK +E I++ +
Sbjct: 740 NDAYETLYYAIKTLMILLAPFIPFITEEIYQNL-KTDEDKQSIHLNDYPKANENFINKTI 798
Query: 831 EREMEFIRRIVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQLNAKE 890
E ++ R+I + R IK+R P+ I I T+++ + + + I+ D++NAKE
Sbjct: 799 EEKINLARKITSMARSLRSLHNIKIRMPISTIYIVTKNQNEQNMLMEMQEIILDEINAKE 858
Query: 891 VKVGRVEREL---TIKPNFAKLGPEFKGDAKI----IAKWINENGRELYEKGELTVEIDG 943
+K+ E EL K NF +LG + D K I+K NE+ ++ +++
Sbjct: 859 MKIKANEEELITYKAKANFKELGKKLGKDMKAVSTEISKLKNEDIIKIINGTSYEIKVAN 918
Query: 944 KTFHLTREHIIVEEKLPDFFVSEEFEGGRVFVDKTLTRELIAEGLAREFVRRIQEMRKRL 1003
+L+ II+E + + E + +D +T+EL EGL REFVR+IQ +RK
Sbjct: 919 AKHYLSLNDIILEREEKENLKVINEESITIGIDSLITKELYLEGLTREFVRQIQNLRKEK 978
Query: 1004 DLDVNDRIIVTIETTDENVELLKENLDYIMRETRADKIVFGKAK 1047
+ DV+DRI + IE + E+L + YI ET A I+ K+K
Sbjct: 979 NFDVSDRINLYIENNETLKEMLNKFEKYIKTETLALNIILNKSK 1022
>sp|P41368|SYIP_STAAU ISOLEUCYL-TRNA SYNTHETASE, MUPIROCIN RESISTANT (ISOLEUCINE--TRNA
LIGASE) (ILERS) (MUPIROCIN RESISTANCE PROTEIN)
>gi|581558|emb|CAA53189.1| (X75439) isoleucyl tRNA
synthetase [Staphylococcus aureus]
Length = 1024
Score = 640 bits (1632), Expect = 0.0
Identities = 372/1029 (36%), Positives = 574/1029 (55%), Gaps = 67/1029 (6%)
Query: 16 EEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRTM 75
+ ++ FW+ +I++K + RK + F DGPP +G H G ++IKD++ R +TM
Sbjct: 9 QNEISAFWNTQKIFKKSIDNRKGQESFVFYDGPPTANGLPHAGHVLGRVIKDLVARLKTM 68
Query: 76 QGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIMTE 135
QG+ V R+ G+D HGLP+E++VE+ +G+K K++IE K G+ENFI +CK+ N K +
Sbjct: 69 QGFYVERKAGWDTHGLPVELEVEKKIGIKGKQDIE-KYGIENFINECKKSVFNYEKEWRD 127
Query: 136 QFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHE 195
K LG W+D D+PY+T++N YIES W L +KGLL K +V +C +TAL+ HE
Sbjct: 128 FSKDLGYWVDMDSPYITLENNYIESVWNILSTFHKKGLLYKGHKVTPYCTHDQTALSSHE 187
Query: 196 VRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVKVKVEFNG 255
V YK KD S VKF + ++ Y L WTTTPWTLPAN+A++ + D +Y K++VE
Sbjct: 188 VAQGYKNVKDLSAVVKFQLTNSKDTYFLSWTTTPWTLPANVALAINKDLNYSKIRVE--- 244
Query: 256 REEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFKEKYEWA 315
EY+ILA L++ ++ E K E+++ F G L L+Y+ P + + A
Sbjct: 245 -NEYYILATDLINSIITE---KYEIIDTFSGSNLINLKYIP------PFESDGLVN---A 291
Query: 316 HRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTE--GKWKGIY 373
+ V+ +FVT EGTG+VH AP HGE+D+++ + L + + +G Y + + G
Sbjct: 292 YYVVDGEFVTNSEGTGIVHIAPAHGEDDYQLVLERDLDFLNVITREGVYNDRFPELVGNK 351
Query: 374 VKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKDKIIKE 433
K +D +II+ L +K L K + EH YPHCWRC PLI+ A + WF+K + K++II
Sbjct: 352 AKNSDIEIIKLLSKKQLLYKKQKYEHNYPHCWRCGNPLIYYAMEGWFIKTTNFKNEII-N 410
Query: 434 NDEKVTWYPDWVKI-RFDNGVRDSGDWVISRQRYWGIPLPIWQSED-GEIYVVGSWRELV 491
N+ + W+P +K R N + + DW I R RYWG PL +W D Y S ++L
Sbjct: 411 NNNNIEWFPSHIKEGRMGNFLENMVDWNIGRNRYWGTPLNVWICNDCNHEYAPSSIKDL- 469
Query: 492 ELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFII---KVNGKDMRRVKD 548
+ I+E + +LHRPYVD + K NGK M RV++
Sbjct: 470 ------------------QNNSINKIDEDI---ELHRPYVDNITLSCPKCNGK-MSRVEE 507
Query: 549 VVDVWFDSGIASWASLGYP-RNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVAFDTV 607
V+DVWFDSG +A YP N+++F + +PADFI EG DQ WFYS S +
Sbjct: 508 VIDVWFDSGSMPFAQHHYPFDNQKIFNQHFPADFIAEGVDQTRGWFYSLLVISTILKGKS 567
Query: 608 PYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENLKFSWK 667
Y+R G++LD G KMSKS GN+I P E++ + G D+ R+ ++ + PW N +FS
Sbjct: 568 SYKRALSLGHILDSNGKKMSKSKGNVINPTELINKYGADSLRWALISDSAPWNNKRFSEN 627
Query: 668 GVEQVR-RMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISEVE 726
V Q + + ++ L N+Y + Y +D+++P N D W LSR+N+LI E
Sbjct: 628 IVAQTKSKFIDTLDNIYKFYNMYNKIDHYNPN--NEITKSRNTLDNWALSRLNTLIKESN 685
Query: 727 NGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFDVLLR 786
+ ++ T A R L N +S WY+ R R W +G DK AY TL+++ L R
Sbjct: 686 IYVNNYDFTSAAR-LINEYTNTISNWYIGDSRGRFWEQGISNDKKDAYNTLYEILTTLSR 744
Query: 787 LLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREMEFIRRIVEAGSA 846
L+APF P+I+E+I+ NL +SVH+ D+P+ E I++ LE EM + +IVE
Sbjct: 745 LVAPFVPFISEKIHYNL-----TGKSVHLQDYPQYKESFINQALEDEMHTVIKIVELSRQ 799
Query: 847 ARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQLNAKEVKV-GRVERELT--IK 903
AR+ A +K++ P+ +++I+ + + I++D+LN K +++ + +T +K
Sbjct: 800 ARKNADLKIKQPLSKMVIKPNSQLNLSFLPNYYSIIKDELNIKNIELTDNINDYITYELK 859
Query: 904 PNFAKLGPEFKGDAKIIAKWINENGRELYEKGELTVEIDGKTF----HLTREHIIVEEKL 959
NF+ +GP+ K I I+ Y+K L + K+ LT++ I++
Sbjct: 860 LNFSSVGPKLGNKTKNIQTLIDSLSE--YDKKSLIESNNFKSLSSDAELTKDDFIIKTLP 917
Query: 960 PDFFVSEEFEGGRVFVDKTLTRELIAEGLAREFVRRIQEMRKRLDLDVNDRIIVTIETTD 1019
D + E + +DK L+ ELI EG ARE +R IQ++RK+ +L +N RI + I T
Sbjct: 918 KDSYQLSEDNDCVILLDKNLSPELIREGHARELIRLIQQLRKKKNLPINQRIDIYIGVTG 977
Query: 1020 ENVELLKEN 1028
E +E +K N
Sbjct: 978 ELLESIKTN 986
>sp|P56690|SYI_THETH ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|4930049|pdb|1ILE| Isoleucyl-Trna Synthetase
Length = 821
Score = 639 bits (1631), Expect = 0.0
Identities = 351/864 (40%), Positives = 508/864 (58%), Gaps = 59/864 (6%)
Query: 2 IKEPEFREYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAW 61
+ EP F KLEE+V FW +I++K E RK GP+Y +GPP +G H+G A
Sbjct: 5 VGEPNF-----PKLEEEVLAFWKREKIFQKSVENRKGGPRYTVYEGPPTANGLPHVGHAQ 59
Query: 62 NKIIKDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKK 121
+ KD+ R++TM+GY R+ G+D HGLP+E++VE+ LGLK+K+EIE G+E F +
Sbjct: 60 ARSYKDLFPRYKTMRGYYAPRRAGWDTHGLPVELEVEKKLGLKSKREIEA-YGIERFNQA 118
Query: 122 CKEFALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVL 181
C+E K + + W+D ++ Y T++ YIES W++LK +++GLL +D +V+
Sbjct: 119 CRESVFTYEKEWEAFTERIAYWVDLEDAYATLEPTYIESIWWSLKNLFDRGLLYRDHKVV 178
Query: 182 HWCPRCETALAEHEVRGEYKLRKDPSIYVKFPVE-----GKENEYLLIWTTTPWTLPANL 236
+CPRC T L+ HEV YK +DPS+YV+FP++ G E LLIWTTTPWTLP N+
Sbjct: 179 PYCPRCGTPLSSHEVALGYKEIQDPSVYVRFPLKEPKKLGLEKASLLIWTTTPWTLPGNV 238
Query: 237 AVSAHPDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVH 296
A + HP+Y Y +V +E IL + L K+LGE +V++ F G+ LEGL Y
Sbjct: 239 AAAVHPEYTYAAFQVG----DEALILEEGLGRKLLGE---GTQVLKTFPGKALEGLPYT- 290
Query: 297 ILMDEYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYS 356
YP + E + V+LAD+V+ E+GTG+VH AP G ED E + YGLP+
Sbjct: 291 ---PPYP------QALEKGYFVVLADYVSQEDGTGIVHQAPAFGAEDLETARVYGLPLLK 341
Query: 357 PLDDQGKYTEGKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRAT 416
+D++GK +KG+Y +EA+ I+ LR +G L K H YPHCWRC TPL++ AT
Sbjct: 342 TVDEEGKLLVEPFKGLYFREANRAILRDLRGRGLLFKEESYLHSYPHCWRCSTPLMYYAT 401
Query: 417 DQWFLKISKVKDKIIKENDEKVTWYPDWVKI-RFDNGVRDSGDWVISRQRYWGIPLPIWQ 475
+ WF+K + KD++I+ N E + W P +K R+ +++ DW +SR RYWG PLPIW
Sbjct: 402 ESWFIKNTLFKDELIRNNQE-IHWVPPHIKEGRYGEWLKNLVDWALSRNRYWGTPLPIWV 460
Query: 476 SED-GEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAF 534
+ G+ +GS++EL A LPE P D HRPYVD
Sbjct: 461 CQACGKEEAIGSFQELKARATK--------PLPE--------------PFDPHRPYVDQV 498
Query: 535 -IIKVNGKDMRRVKDVVDVWFDSGIASWASLGYP-RNKELFEKLWPADFIVEGEDQVTKW 592
+ G MRRV V+DVW+DSG +ASL YP ++E+F + +PADFI EG DQ W
Sbjct: 499 ELACACGGTMRRVPYVIDVWYDSGAMPFASLHYPFEHEEVFRESFPADFIAEGIDQTRGW 558
Query: 593 FYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYM 652
F S ++ F ++ ++ V HG +LDEKG KMSKS GN++ P +++ + G D R+Y+
Sbjct: 559 FNSLHQLGVMLFGSIAFKNVICHGLILDEKGQKMSKSKGNVVDPWDIIRKFGADALRWYI 618
Query: 653 LWATNPWENLKFSWKGV-EQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREED 711
+ P + +F V E VR LWNVY TY +LD D + P E E D
Sbjct: 619 YVSAPPEADRRFGPNLVRETVRDYFLTLWNVYSFFVTYANLDRPDLKNPPPPE-KRPEMD 677
Query: 712 KWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKL 771
+W+L+R+ LI V +E++ T + RAL +FVVEDLS+WYVR R+R W + D+
Sbjct: 678 RWLLARMQDLIQRVTEALEAYDPTTSARALRDFVVEDLSQWYVRRNRRRFWKNEDALDRE 737
Query: 772 AAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRP--FTNVESVHMLDWPKVDEKAIDEE 829
AAY TL++ ++ L APFTP++AE ++QNL+R ESVH+ DWP+ D DE
Sbjct: 738 AAYATLYEALVLVATLAAPFTPFLAEVLWQNLVRSVRLEAKESVHLADWPEADPALADEA 797
Query: 830 LEREMEFIRRIVEAGSAARQRAKI 853
L +M + ++V+ AAR ++ +
Sbjct: 798 LVAQMRAVLKVVDLARAARAKSGV 821
>emb|CAC12008.1| (AL445065) isoleucyl-tRNA synthetase related protein [Thermoplasma
acidophilum]
Length = 1014
Score = 625 bits (1595), Expect = e-178
Identities = 362/1056 (34%), Positives = 584/1056 (55%), Gaps = 84/1056 (7%)
Query: 13 KKLEEKVEKFWSENEIYRKVKELRKDGPK-YYFLDGPPYVSGAIHLGTAWNKIIKDMIIR 71
++++ ++ K+W + I K+ L K G K + FL+GPP +G H+G A + IKD+++R
Sbjct: 4 REIDSEILKYWKDKNILEKI--LSKGGSKKFVFLEGPPTANGRPHIGHAMTRTIKDIVLR 61
Query: 72 FRTMQGYNVWRQPG-YDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNL 130
+ TM + ++R+ G +D HGLP+E++ E+ G TK EI GVE F + C+E +
Sbjct: 62 YNTMTDHKIYRRVGGWDCHGLPVELEAEKHFGFHTKSEIVN-FGVEKFNQYCRESIFRYI 120
Query: 131 KIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETA 190
+ ++G +D + Y+T++N+Y+ES WF LK + GLL KD V+ +CPRCET+
Sbjct: 121 DEWKQVDDLIGFSIDHNGDYITLRNDYMESEWFALKTMYNSGLLYKDYTVVPYCPRCETS 180
Query: 191 LAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVKVK 250
L+ HEV YK KDPS+YV+F +EN Y + WTTTPWTLP+N + +PD +Y
Sbjct: 181 LSSHEVAQGYKDVKDPSVYVRFKSADEENTYFVAWTTTPWTLPSNEFLVVNPDMEY--SL 238
Query: 251 VEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFKE 310
VE G Y ++A G I + + GR+L G RY+ ++ F +
Sbjct: 239 VEAQGSRYYVASSRA------GYIFKEYREIRRMHGRDLVGKRYLQLM--------PFLD 284
Query: 311 KYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTEGK-- 368
+ +V+ FVT E+G+G+VH AP G +D+++G++ G+ + +P+D G++ + +
Sbjct: 285 PPSGSLKVVAGSFVTSEDGSGIVHAAPAFGADDYQIGKEEGVEILNPVDKNGRFADPRIP 344
Query: 369 WKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKD 428
W G +V++A+ II +L++ L+K+ + EH YP C+RC TPL++ D WF+ +S+++D
Sbjct: 345 WNGKFVRDANEDIIVYLKKNQMLLKSEKYEHSYPFCYRCDTPLLYYPLDAWFIAVSRIRD 404
Query: 429 KIIKENDEKVTWYPDWVKI-RFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSW 487
K+++ N E++ W PD++K RF N + ++ DW +SR R+WG PLP W+ ++G + VGS
Sbjct: 405 KLVEYN-ERINWKPDYLKHGRFGNFLGEAKDWNLSRDRFWGTPLPAWRCKNGHLVFVGSR 463
Query: 488 RELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVD--AFIIKVNGKDMRR 545
+E+ +L + PEDLHRPY+D F G++M R
Sbjct: 464 KEIEDLGGKV-------------------------PEDLHRPYIDEVRFKCPTCGEEMSR 498
Query: 546 VKDVVDVWFDSGIASWASLGYPRNKELF-EKLWPADFIVEGEDQVTKWFYSQQAASIVAF 604
V+D WFDSG A++A+ YP K E P FI E DQ WFY + + F
Sbjct: 499 EPYVIDTWFDSGSATYAASHYPFEKNFDPETDVPVSFITEAIDQTRGWFYVLHVIATIMF 558
Query: 605 DTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENLKF 664
+ Y ++LD +G KMSKS GN + + + D+ R + L+ PW++
Sbjct: 559 NKNAYESALSINFILDAQGRKMSKSKGNSVYALDFLNEVPPDSLRLFFLYGA-PWKSKNL 617
Query: 665 SWKGVEQV-RRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLIS 723
K +++V R+ L + NVY + ++DNF + N +L D++++S+VNS +
Sbjct: 618 DKKVIDEVSRKTLMTVLNVYSFFAYNANIDNF---QWNGLQLSGNALDRYMVSKVNSFVR 674
Query: 724 EVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFDV 783
+ ES + RA F V+DLS +Y+RL R+R W EG D DKL+AY TL+
Sbjct: 675 SSRDAYESLDFHEVVRASMEF-VDDLSNFYLRLSRRRFWAEGFDDDKLSAYSTLYYALKA 733
Query: 784 LLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREMEFIRRIVEA 843
++AP TP+ ++ IY NL + ESVH+ +P+ D +DE+LE EM+ ++E
Sbjct: 734 FSEVMAPITPFFSDFIYLNL---GGDKESVHLEAFPEFDSTLMDEKLESEMDRAYSVIET 790
Query: 844 GSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQLNAKEVKVGRVERE---L 900
RQ IK R P+R I+I + E E + +++ +LNAK++K+ ++E L
Sbjct: 791 VRRLRQENSIKGRQPLREILIAGDME------ESIIDVVKSELNAKDIKLIERDQEPIRL 844
Query: 901 TIKPNFAKLGPEFKGDAKIIAKWIN-----ENGRELYEKGELTVEIDGKTFHLTREHIIV 955
+ + P + + I E R++ EKG VEIDG ++
Sbjct: 845 SADLRMDRAAPVLRSRVNAVRHKIRSMDGLEVQRQISEKG--FVEIDGVRLD---PDMVE 899
Query: 956 EEKLPD---FFVSEEFEGGRVFVDKTLTRELIAEGLAREFVRRIQEMRKRLDLDVNDRII 1012
++PD + E G VF++K + R+ EGLARE VRRIQ MRK ++L+ DRII
Sbjct: 900 ISRVPDPNYAYSQTEKYGIDVFINKNIDRDGYLEGLARELVRRIQVMRKEMNLNYTDRII 959
Query: 1013 VTIETTDENVELLKENLDYIMRETRADKIVFGKAKG 1048
++ +D+ +E L ++ +YI ET++D I+ K +G
Sbjct: 960 THLDLSDDFLEALNKHAEYIKNETQSDSIITDKVEG 995
>pir||E75407 isoleucyl-tRNA synthetase - Deinococcus radiodurans (strain R1)
>gi|6459088|gb|AAF10907.1|AE001980_2 (AE001980)
isoleucyl-tRNA synthetase [Deinococcus radiodurans]
Length = 1078
Score = 618 bits (1577), Expect = e-176
Identities = 370/1096 (33%), Positives = 581/1096 (52%), Gaps = 87/1096 (7%)
Query: 4 EPEFREYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNK 63
+P FR+ LE + + W + +++ + + ++ F +GPP +G L +
Sbjct: 12 QPNFRQ-----LEADILQKWKDEQVFEQTQTRPAPAGEFVFYEGPPTANGKPALHHVLAR 66
Query: 64 IIKDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCK 123
KD+ RF+ MQG++V R+ G+D HGLP+E+ VE+ LG + + +E F + C+
Sbjct: 67 SFKDLFPRFKVMQGHHVTRKGGWDTHGLPVEISVEKKLGWLGRNHGASREELEEFNRLCR 126
Query: 124 EFALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHW 183
++ E + +G W+D +PY+T +N Y+ES W L+R EKGL+ +D +V+
Sbjct: 127 TSVWETIQDWNELTERMGYWLDLGDPYITYQNSYVESVWNLLRRLHEKGLVAQDYKVVPL 186
Query: 184 CPRCETALAEHEVRGE---YKLRKDPSIYVKFPV------------------EGKENEYL 222
PR + L+ E+ GE Y++ DPS+YV+ P+ E ++ L
Sbjct: 187 SPRISSTLSRAEL-GEVDSYRMVDDPSVYVRLPIVWDTLPERAHAALSSLSGEQRQGLSL 245
Query: 223 LIWTTTPWTLPANLAVSAHPDYDYVKVKVEFNGREEYWILAKALVDKV--LGEIGVKGEV 280
L+WTTTPWTLP+N + +PD DYV V +GR I+A+ V+++ L + EV
Sbjct: 246 LVWTTTPWTLPSNTLAAVNPDLDYV-VADSPSGRV---IVAEGAVERLSALHKDAAPLEV 301
Query: 281 VEEFKGRELEGLRY------VHILMDEYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVH 334
+ FKGR+LE + Y V + E ++ H V++ADFV+ +G+G+ H
Sbjct: 302 LARFKGRDLEWVEYEPPFPEVASQLGVVSELHERRDGKPVLHFVVMADFVSDVDGSGVAH 361
Query: 335 TAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTEGKWKGIYVKEADPKIIEHLREKGYLVKA 394
AP +G ED EV + YG+P+ +DD G +G + K+AD +I ++ +G + A
Sbjct: 362 EAPAYGAEDLEVARAYGVPLMFGVDDHGILQVTHEQGKFFKDADKGLIADMKARGLMFWA 421
Query: 395 GEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKDKIIKENDEKVTWYPDWVKI-RFDNGV 453
G ++H+YP R P+++ A W+++ S+V +++ +N EK+ W P +K RF N +
Sbjct: 422 GTLKHRYPFHDRTGDPILYFAKKGWYIRTSQVAGEMLAQN-EKINWVPGNIKHGRFGNWL 480
Query: 454 RDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEK 513
+ DW ISR+RYWG PLP WQSE G++ V+GS EL ELA
Sbjct: 481 EGNVDWAISRERYWGTPLPFWQSESGQLRVIGSVAELSELA------------------- 521
Query: 514 LKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGY------- 566
L DLHRPY+D ++G++ RRV +V+DVWFDSG +A G
Sbjct: 522 ----GRDLSDLDLHRPYIDDITFTLDGEEYRRVPEVLDVWFDSGSMPYAQWGLLLNEQGE 577
Query: 567 -PRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDK 625
R E F K +PAD+I E DQ WFYS A S + +D Y+ V G+++DEKG K
Sbjct: 578 AVRGAEQFAKHYPADYICEAIDQTRGWFYSLHAISTMLYDQPAYKNVICLGHIVDEKGLK 637
Query: 626 MSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENLKFSWKGVEQVRR-MLNILWNVYV 684
MSKS GN++ P + ++ G D+ R+YM A++P + +FS + V + +R +N LWNVY
Sbjct: 638 MSKSKGNVVAPLPLFDQYGADSVRWYMFMASDPGDQKRFSERLVAEAQRSYVNTLWNVYS 697
Query: 685 LASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISEVENGIESFYLTKATRALYNF 744
Y +LD D P E D+W+L+R+ + +V +ES+ RAL F
Sbjct: 698 FFVLYANLDQPD-LAAAPAVAERPEMDRWLLARLEETVRDVTAALESYDARSGGRALEGF 756
Query: 745 VVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLI 804
V+DLS WYVR R R W EG D AAY TL + V+ +L APFTP++A+ +Y+NL
Sbjct: 757 -VDDLSNWYVRRSRSRFWGEGGTVD-TAAYATLHEALLVVSQLTAPFTPFLADALYRNL- 813
Query: 805 RPFTNVESVHMLDWPKVDEKAIDEELEREMEFIRRIVEAGSAARQRAKIKLRYPVRRIII 864
SVH+ WP V + +D +L +M + ++VE G A R +K R P+ + +
Sbjct: 814 --SGEESSVHLTPWPTVRAERLDRKLTADMAAVMKVVELGRAVRGAHNLKTRQPLAGVQV 871
Query: 865 ETEDETVKKAVERLNRILRDQLNAKEVKVGRVEREL---TIKPNFAKLGPEFKGDAKIIA 921
A++R + ++LN K V + +L +++PN +G ++ ++
Sbjct: 872 RAASPEALDALKRSQTQIMEELNVKAVTFLEGDTDLVQYSLRPNLPVVGKQYGKQLPVLK 931
Query: 922 KWINENGRE----LYEKGE-LTVEIDGKTFHLTREHIIVEEKLPDFFVSEEFEGGRVFVD 976
K + E + G+ +V+ DG TF LT ++V+ K P+ + E G V D
Sbjct: 932 KALTEADARAVATAVQAGQGFSVQADGVTFDLTPGSVLVDAKAPEGVAAAEDAGYLVAFD 991
Query: 977 KTLTRELIAEGLAREFVRRIQEMRKRLDLDVNDRIIVTIETTDENVELLKENLDYIMRET 1036
LT EL+ EGLAR+ VR IQE RK +V DRI + +E E +E + D+I E
Sbjct: 992 TALTPELVREGLARDLVRAIQEARKAAGFEVQDRIALALELDGEALEAAQAWQDFIAGEV 1051
Query: 1037 RADKIVFGKAKGYVVE 1052
A+++ +G +G+ E
Sbjct: 1052 LAEQVAYGSGEGFRAE 1067
>sp|O84022|SYI_CHLTR ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|7437566|pir||F71565 probable isoleucine--tRNA ligase
(EC 6.1.1.5) - Chlamydia trachomatis (serotype D, strain
UW3/Cx) >gi|3328409|gb|AAC67609.1| (AE001277)
Isoleucyl-tRNA Synthetase [Chlamydia trachomatis]
Length = 1036
Score = 614 bits (1565), Expect = e-174
Identities = 365/1037 (35%), Positives = 565/1037 (54%), Gaps = 61/1037 (5%)
Query: 16 EEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRTM 75
EEK+ FW E +I++K + R+ P + F DGPP+ +G H G IKD++ R+ +M
Sbjct: 13 EEKILSFWKEQDIFQKTLDNREGCPTFSFYDGPPFATGLPHYGHLLAGTIKDVVCRYASM 72
Query: 76 QGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIMTE 135
G+ V R+ G+D HG+P+E +VE++LGL T+ E+ GV NF ++C++
Sbjct: 73 DGHYVPRRFGWDCHGVPVEYEVEKSLGL-TEPGAIERFGVANFNEECRKIVFRYADEWKY 131
Query: 136 QFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHE 195
+G W+D+ + T+ ++ES W+ + +++GL+ + +V+ + + T L+ E
Sbjct: 132 FVDRIGRWVDFSATWRTMDLSFMESVWWVFRSLYDQGLVYEGTKVVPFSTKLGTPLSNFE 191
Query: 196 VRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVKVKVEFNG 255
YK DPS+ VKF ++ + +LL WTTTPWTL +N+A++ HP+ YV++K + +G
Sbjct: 192 AGQNYKEVDDPSVVVKFALQDNQG-FLLAWTTTPWTLVSNMALAVHPELTYVRIKDKESG 250
Query: 256 REEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFKEKYEWA 315
E +IL + + + + E + + G+ L G Y L + +KE + A
Sbjct: 251 DE--YILGQESLPRWFPD-RESYEWIGQLSGKSLVGQSY-EPLFPYFQDKKELE-----A 301
Query: 316 HRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTE--GKWKGIY 373
R++ ADF+ EGTG+VH AP GE DF Q++ +P+ P+D+QG YT + G Y
Sbjct: 302 FRILPADFIEESEGTGIVHMAPAFGEADFFACQEHNVPLVCPVDNQGCYTAEVKDFVGEY 361
Query: 374 VKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKDKIIKE 433
+K AD I L+ + L G + H+YP CWR +PLI++A + WF+ + KVK K++K
Sbjct: 362 IKSADKGIARRLKNENKLFYQGTVRHRYPFCWRTDSPLIYKAVNSWFVAVEKVKSKMLKA 421
Query: 434 NDEKVTWYPDWVKI-RFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVE 492
N E + W P+ +K RF + + DW ISR RYWG P+PIW+S+DGE+ V+GS +EL
Sbjct: 422 N-ESIHWTPEHIKQGRFGKWLEGARDWAISRNRYWGTPIPIWRSDDGELLVIGSIQELEA 480
Query: 493 LAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDV 552
L +G++I DLHR ++D I NGK RR+ V D
Sbjct: 481 L------SGQKI-------------------VDLHRHFIDEIEINQNGKSFRRIPYVFDC 515
Query: 553 WFDSGIASWASLGYP-RNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVAFDTVPYRR 611
WFDSG +A YP E E +PADFI EG DQ WFY+ + FD ++
Sbjct: 516 WFDSGAMPYAQNHYPFERAEETEACFPADFIAEGLDQTRGWFYTLTVIAAALFDQPAFKN 575
Query: 612 VAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYML-WATNPWENLKFSWKGVE 670
V ++G +L E G+KMSK L N P+ +++ G D R Y+L E+L+FS KGVE
Sbjct: 576 VIVNGIILAEDGNKMSKRLNNYPSPKMIMDAYGADALRLYLLNSVVVKAEDLRFSDKGVE 635
Query: 671 QV-RRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISEVENGI 729
V +++L L N TY L FDP++ D + E D+WILS + SL+ + +
Sbjct: 636 SVLKQVLLPLSNALAFYKTYAELYGFDPKE--TDNIELAEIDRWILSSLYSLVGKTRESM 693
Query: 730 ESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFDVLLRLLA 789
+ L A +F +EDL+ WY+R R+R W + D+ AA+ TL++V V +++A
Sbjct: 694 SQYDLHAAVNPFVDF-IEDLTNWYIRRSRRRFWDAEDSADRRAAFSTLYEVLVVFSKVIA 752
Query: 790 PFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREMEFIRRIVEAGSAARQ 849
PF P+IAE++YQ L R T+ ESVH+ D+P V + I +LER+M+ IR IV G + R+
Sbjct: 753 PFIPFIAEDMYQQL-RGETDPESVHLCDFPHVVLEKILPDLERKMQDIREIVALGHSLRK 811
Query: 850 RAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQLNAKEVKVGRVERELT---IKPNF 906
K+K+R P++ + I E K+A+ ++ ++ ++LN K+V E IKPNF
Sbjct: 812 EHKLKVRQPLQNVYIVGSKER-KEALAQVGSLIGEELNVKDVHFCSETPEYVTTLIKPNF 870
Query: 907 AKLG-------PEFKGDAKIIAKWINENGRELYEKGELTVEIDGKTFHLTREHIIVEEKL 959
LG PE + + +A E + KG++ V + +T L +E I V
Sbjct: 871 RTLGKKVGNRLPEIQ---RALAGLPQEQIQAFMHKGQMVVSLGEETISLDKEDITVSWAS 927
Query: 960 PDFFVSEEFEGGRVFVDKTLTRELIAEGLAREFVRRIQEMRKRLDLDVNDRIIVTIETTD 1019
+ FV+ +D LT LI EG+ARE V +I MR+ L V+DRI + +
Sbjct: 928 AEGFVARSSASFVAVLDCQLTEPLIMEGIARELVNKINTMRRNRKLHVSDRIAIRLHAPV 987
Query: 1020 ENVELLKENLDYIMRET 1036
E + +YI ET
Sbjct: 988 IVQEAFALHKEYICEET 1004
>sp|Q9Z972|SYI_CHLPN ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|7437565|pir||E72118 isoleucine--tRNA ligase (EC
6.1.1.5) - Chlamydophila pneumoniae (strain CWL029)
>gi|4376371|gb|AAD18262.1| (AE001597) Isoleucyl-tRNA
Synthetase [Chlamydophila pneumoniae CWL029]
>gi|8978483|dbj|BAA98320.1| (AP002545) isoleucyl-tRNA
synthetase [Chlamydophila pneumoniae J138]
Length = 1043
Score = 611 bits (1559), Expect = e-173
Identities = 357/1036 (34%), Positives = 567/1036 (54%), Gaps = 54/1036 (5%)
Query: 14 KLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFR 73
K EE+V KFW +N+I+ K + R+ Y F DGPP+ +G H G IKD++ R+
Sbjct: 13 KKEEQVLKFWKDNQIFEKSLQNRQGKTLYSFYDGPPFATGLPHYGHLLASTIKDVVGRYA 72
Query: 74 TMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIM 133
TM GY V R+ G+D HG+P+E +VE++L L IE+ G+ +F ++C++ +
Sbjct: 73 TMDGYYVPRRFGWDCHGVPVEYEVEKSLSLTAPGAIED-FGIASFNEECRKIVFRYVHEW 131
Query: 134 TEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAE 193
+G W+D+ + + T+ ++ES W+ + + +GL+ + +V+ + T L+
Sbjct: 132 EYYINRIGRWVDFSSTWKTMDASFMESVWWVFQSLYNQGLVYEGTKVVPFSTALGTPLSN 191
Query: 194 HEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVKVKVEF 253
E YK DPS+ V+ P++ ++ LL+WTTTPWTLP+N+A++ YV+++ +
Sbjct: 192 FEASQNYKEVDDPSLVVRMPLQ-NDSASLLVWTTTPWTLPSNMAIAVGETLVYVRIQDKK 250
Query: 254 NGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFKEKYE 313
+G E WIL++ V + + ++E F G++L G Y E P ++ E
Sbjct: 251 SG--EQWILSQGCVSRWFSN-PEEFVILESFSGKDLVGRTY------EPPFTFFQSKREE 301
Query: 314 WAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTE--GKWKG 371
A RVI A FV EGTG+VH AP GE DF V ++ +P+ P+D G +TE +++G
Sbjct: 302 GAFRVIAASFVEESEGTGVVHMAPAFGEGDFLVCKENHVPLVCPVDAHGSFTEEIPQYQG 361
Query: 372 IYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKDKII 431
Y+K AD +II+ L+++G + G ++H+YP CWR TPLI++A + WF+ + K+KDK++
Sbjct: 362 QYIKHADKEIIKFLKKEGRIFYHGTVKHRYPFCWRTDTPLIYKAVNSWFVAVEKIKDKML 421
Query: 432 KENDEKVTWYPDWVKI-RFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWREL 490
+ N + W P+ ++ RF + + DW ISR RYWG P+PIW+S DGEI VVGS REL
Sbjct: 422 RAN-SSIHWVPEHIQEGRFGKWLEGARDWAISRNRYWGTPIPIWKSADGEILVVGSIREL 480
Query: 491 VELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVV 550
EL G +I D+HR ++D I +GK R+ V
Sbjct: 481 EEL------TGTQI-------------------TDIHRHFIDDLNIVKDGKPFHRIPYVF 515
Query: 551 DVWFDSGIASWASLGYP-RNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVAFDTVPY 609
D WFDSG +A YP N++ E+ +PADFI EG DQ WFY+ S + FD +
Sbjct: 516 DCWFDSGAMPYAQNHYPFENQKETEEAFPADFIAEGLDQTRGWFYTLTVISAILFDRPAF 575
Query: 610 RRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWA-TNPWENLKFSWKG 668
R ++G +L E G+KMSK L N P+ V++ G D R Y+L + E+L+FS KG
Sbjct: 576 RNAIVNGIILAEDGNKMSKRLNNYPSPKYVLDTYGADALRLYLLHSVVVKAEDLRFSDKG 635
Query: 669 VEQV-RRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISEVEN 727
+E V +++L L NV +TY L FDP K E + E D+WILS + S++ +V
Sbjct: 636 IEGVLKQILLPLTNVLSFFNTYAELYGFDP-KSQDIEPAYTEIDQWILSNLYSVVGKVRE 694
Query: 728 GIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFDVLLRL 787
+ ++L A F ++DL+ WY+R R+R W + PD+ AA+ TL++V V ++
Sbjct: 695 SMSQYHLNFAVEPFVTF-IDDLTNWYIRRCRRRFWEAEDTPDRRAAFSTLYEVLTVFCKV 753
Query: 788 LAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREMEFIRRIVEAGSAA 847
+APF P++AE+IYQ L + ESVH+ D+P+V+ I +LE+ M IR IV G +
Sbjct: 754 IAPFVPFLAEDIYQKL-KLEKEPESVHLCDFPQVEMDKILPDLEKRMHDIREIVGLGHSL 812
Query: 848 RQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQLNAKEVKVGRVEREL---TIKP 904
R+ K+K+R P+ + + + ++ ++ ++LN K V T+KP
Sbjct: 813 RKEHKLKVRQPLANFYVVGSKDRL-SLLKTFEGLIAEELNVKNVIFYEEAPSFIYTTVKP 871
Query: 905 NFAKLGPEFKGDAKIIAKWINENGR----ELYEKGELTVEIDGKTFHLTREHIIVEEKLP 960
NF LG + K + K ++E +L ++ + ID + L + +++
Sbjct: 872 NFRMLGKKVGSKMKEVQKALSELPNNAIDKLIQEETWVLTIDDREIALDGDDVVICRHTD 931
Query: 961 DFFVSEEFEGGRVFVDKTLTRELIAEGLAREFVRRIQEMRKRLDLDVNDRIIVTIETTDE 1020
+++ V +D L LI EG+ARE V +I MR+ L V+DRI + I+TT+
Sbjct: 932 PGYIARSSALFSVILDCQLREPLIVEGIARELVNKINTMRRNQQLHVSDRIALRIKTTEA 991
Query: 1021 NVELLKENLDYIMRET 1036
+ +YI ET
Sbjct: 992 VHRAFLDYENYICEET 1007
>pir||C81552 isoleucyl-tRNA synthetase CP0665 [imported] - Chlamydophila
pneumoniae (strain AR39) >gi|7189579|gb|AAF38477.1|
(AE002224) isoleucyl-tRNA synthetase [Chlamydophila
pneumoniae AR39]
Length = 1043
Score = 611 bits (1558), Expect = e-173
Identities = 357/1036 (34%), Positives = 567/1036 (54%), Gaps = 54/1036 (5%)
Query: 14 KLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFR 73
K EE+V KFW +N+I+ K + R+ Y F DGPP+ +G H G IKD++ R+
Sbjct: 13 KKEEQVLKFWKDNQIFEKSLQNRQGKTLYSFYDGPPFATGLPHYGHLLASTIKDVVGRYA 72
Query: 74 TMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIM 133
TM GY V R+ G+D HG+P+E +VE++L L IE+ G+ +F ++C++ +
Sbjct: 73 TMDGYYVPRRFGWDCHGVPVEYEVEKSLSLTAPGAIED-FGIASFNEECRKIVFRYVHEW 131
Query: 134 TEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAE 193
+G W+D+ + + T+ ++ES W+ + + +GL+ + +V+ + T L+
Sbjct: 132 EYYINRIGRWVDFSSTWKTMDASFMESVWWVFQSLYNQGLVYEGTKVVPFSTALGTPLSN 191
Query: 194 HEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVKVKVEF 253
E YK DPS+ V+ P++ ++ LL+WTTTPWTLP+N+A++ YV+++ +
Sbjct: 192 FEASQNYKEVDDPSLVVRMPLQ-NDSASLLVWTTTPWTLPSNMAIAVGETLVYVRIQDKK 250
Query: 254 NGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFKEKYE 313
+G E WIL++ V + + ++E F G++L G Y E P ++ E
Sbjct: 251 SG--EQWILSQGCVSRWFSN-PEEFVILESFSGKDLVGRTY------EPPFTFFQSKREE 301
Query: 314 WAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTE--GKWKG 371
A RVI A FV EGTG+VH AP GE DF V ++ +P+ P+D G +TE +++G
Sbjct: 302 GAFRVIAASFVEESEGTGVVHMAPAFGEGDFLVCKENHVPLVCPVDAHGSFTEEIPQYQG 361
Query: 372 IYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKDKII 431
Y+K AD +II+ L+++G + G ++H+YP CWR TPLI++A + WF+ + K+KDK++
Sbjct: 362 QYIKHADKEIIKFLKKEGRIFYYGTVKHRYPFCWRTDTPLIYKAVNSWFVAVEKIKDKML 421
Query: 432 KENDEKVTWYPDWVKI-RFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWREL 490
+ N + W P+ ++ RF + + DW ISR RYWG P+PIW+S DGEI VVGS REL
Sbjct: 422 RAN-SSIHWVPEHIQEGRFGKWLEGARDWAISRNRYWGTPIPIWKSADGEILVVGSIREL 480
Query: 491 VELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVV 550
EL G +I D+HR ++D I +GK R+ V
Sbjct: 481 EEL------TGTQI-------------------TDIHRHFIDDLNIVKDGKPFHRIPYVF 515
Query: 551 DVWFDSGIASWASLGYP-RNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVAFDTVPY 609
D WFDSG +A YP N++ E+ +PADFI EG DQ WFY+ S + FD +
Sbjct: 516 DCWFDSGAMPYAQNHYPFENQKETEEAFPADFIAEGLDQTRGWFYTLTVISAILFDRPAF 575
Query: 610 RRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWA-TNPWENLKFSWKG 668
R ++G +L E G+KMSK L N P+ V++ G D R Y+L + E+L+FS KG
Sbjct: 576 RNAIVNGIILAEDGNKMSKRLNNYPSPKYVLDTYGADALRLYLLHSVVVKAEDLRFSDKG 635
Query: 669 VEQV-RRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISEVEN 727
+E V +++L L NV +TY L FDP K E + E D+WILS + S++ +V
Sbjct: 636 IEGVLKQILLPLTNVLSFFNTYAELYGFDP-KSQDIEPAYTEIDQWILSNLYSVVGKVRE 694
Query: 728 GIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFDVLLRL 787
+ ++L A F ++DL+ WY+R R+R W + PD+ AA+ TL++V V ++
Sbjct: 695 SMSQYHLNFAVEPFVTF-IDDLTNWYIRRCRRRFWEAEDTPDRRAAFSTLYEVLTVFCKV 753
Query: 788 LAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREMEFIRRIVEAGSAA 847
+APF P++AE+IYQ L + ESVH+ D+P+V+ I +LE+ M IR IV G +
Sbjct: 754 IAPFVPFLAEDIYQKL-KLEKEPESVHLCDFPQVEMDKILPDLEKXMHDIREIVGLGHSL 812
Query: 848 RQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQLNAKEVKVGRVEREL---TIKP 904
R+ K+K+R P+ + + + ++ ++ ++LN K V T+KP
Sbjct: 813 RKEHKLKVRQPLANFYVVGSKDRL-SLLKTFEGLIAEELNVKNVIFYEEAPSFIYTTVKP 871
Query: 905 NFAKLGPEFKGDAKIIAKWINENGR----ELYEKGELTVEIDGKTFHLTREHIIVEEKLP 960
NF LG + K + K ++E +L ++ + ID + L + +++
Sbjct: 872 NFRMLGKKVGSKMKEVQKALSELPNNAIDKLIQEETWVLTIDDREIALDGDDVVICRHTD 931
Query: 961 DFFVSEEFEGGRVFVDKTLTRELIAEGLAREFVRRIQEMRKRLDLDVNDRIIVTIETTDE 1020
+++ V +D L LI EG+ARE V +I MR+ L V+DRI + I+TT+
Sbjct: 932 PGYIARSSALFSVILDCQLREPLIVEGIARELVNKINTMRRNQQLHVSDRIALRIKTTEA 991
Query: 1021 NVELLKENLDYIMRET 1036
+ +YI ET
Sbjct: 992 VHRAFLDYENYICEET 1007
>sp|Q9XDB4|SYI_FERPE ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|4836216|gb|AAD30388.1|AF096862_2 (AF096862)
isoleucyl-tRNA synthase [Fervidobacterium pennivorans]
Length = 897
Score = 606 bits (1546), Expect = e-172
Identities = 342/882 (38%), Positives = 508/882 (56%), Gaps = 71/882 (8%)
Query: 16 EEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRTM 75
E ++ KFW E EIY+K E R + P Y DGPPY +G IHLGTA NKI+KD + R++TM
Sbjct: 9 EPEMLKFWEEKEIYKKTLETRANAPTYLLHDGPPYANGDIHLGTAMNKILKDFVTRYKTM 68
Query: 76 QGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIMTE 135
+GY V PG+D HGLPIE +V +LG + KK+ +I K CKEFAL + I E
Sbjct: 69 RGYRVPFVPGWDTHGLPIEHRVTTSLGEEAKKKSPAEIR-----KLCKEFALKYVDIQRE 123
Query: 136 QFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHE 195
+FK LG+ DW++PY+T+ +Y K E G + + + ++WCP C TALAE E
Sbjct: 124 EFKRLGVKGDWEHPYITLDPDYEYHILDVFKTLVENGNVYRGNKPVYWCPTCRTALAEAE 183
Query: 196 VRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVKVKVEFNG 255
+ EY + PSIYVKF + K + Y++IWTTTPWT+PAN+A++ HPDY YVK+KV+
Sbjct: 184 I--EYHDHESPSIYVKFQMVDKPDTYIVIWTTTPWTIPANVAIALHPDYTYVKIKVD--- 238
Query: 256 REEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFKEKYEWA 315
EEYWI+A+ L+ K ++G+ EVVE+F G+ELEG H L Y+
Sbjct: 239 -EEYWIVAEGLLQKFAADVGIDFEVVEKFVGKELEGKLTKHPL-------------YDRT 284
Query: 316 HRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTE--GKWKGIY 373
V+LAD+VTLE+GTG VHTAPGHGEED++ G KY LPV SP+DD+G++T+ GK++G+
Sbjct: 285 SVVVLADYVTLEDGTGCVHTAPGHGEEDYQTGLKYNLPVLSPVDDEGRFTKEAGKYEGLK 344
Query: 374 VKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISK--VKDKII 431
+ +A+ I+E L+ G L+KAG+I H YPHCWRCK P++FRAT QWF+ + K ++ K++
Sbjct: 345 IWDANKVIVEDLKNNGSLIKAGKISHSYPHCWRCKGPVMFRATPQWFISVDKNNLRGKVL 404
Query: 432 KENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSED-GEIYVVGSWREL 490
+E +KV WYP W + R V++ DW ISRQR WG+P+P + +D GE
Sbjct: 405 EE-IKKVKWYPAWGETRITAMVQERPDWTISRQRVWGVPIPAVKCKDCGE---------- 453
Query: 491 VELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVV 550
V L + + I + + ++ +L P D P K+ + D +
Sbjct: 454 VTLEPKVIEHFANIVKEKGTDAWFELDVNELIPADFKCP-------ACGSKNFEKTHDTL 506
Query: 551 DVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVAFDTVPYR 610
DVW DSG SW ++ + + +P D +EG+DQ WF S S T P++
Sbjct: 507 DVWMDSG-CSWEAVIRSKGER-----FPVDLYLEGDDQHRGWFQSSIFLSTAKAGTAPFK 560
Query: 611 RVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENLKFSWKGVE 670
V HG++ DE+G KMSKSLGN+I P E+V + G D R ++ +T+ ++N++ +E
Sbjct: 561 AVVTHGFIKDEQGRKMSKSLGNVIDPMEIVNKYGADILRLWVA-STDFFDNIRVGKNIIE 619
Query: 671 QVRRMLNILWNV--YVLASTYMSLDNFDPRKLNPDE--LPFREEDKWILSRVNSLISEVE 726
Q + L N Y+L++ Y +F L P E LP DKW L R+ I ++
Sbjct: 620 QQVEVYRKLRNTLRYLLSNLY----DFTEADLLPYEKLLPL---DKWALGRLQKFIEQIT 672
Query: 727 NGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDP-DKLAAYYTLWKVFDVLL 785
E F +K A + +LS Y+ +++ RL+VE +D + +A L + + L+
Sbjct: 673 QYYEGFEYSKVYNATVKYCTTELSAVYLDILKDRLYVEAKDSIYRRSAQTALHYILEALI 732
Query: 786 RLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREMEFIRRIVEAGS 845
++LAP P+ AEE YQ ESVH+ WP+V ++ IDE L E + + I +
Sbjct: 733 KILAPIIPFTAEEAYQE--SHLKRYESVHLEYWPEVRKEFIDEALLEEFDHLLLIRDDVL 790
Query: 846 AARQRAKIK--LRYPV-RRIIIETEDETVKKAVERLNRILRD 884
A + A+ + + + +IIE ++E +K + + +L +
Sbjct: 791 KALENARASDIIGHSLDAHVIIEAKNEELKNLLRKYESLLEE 832
>pir||F81719 isoleucyl-tRNA synthetase TC0288 [imported] - Chlamydia muridarum
(strain Nigg) >gi|7190330|gb|AAF39156.1| (AE002296)
isoleucyl-tRNA synthetase [Chlamydia muridarum]
Length = 1036
Score = 600 bits (1530), Expect = e-170
Identities = 364/1044 (34%), Positives = 558/1044 (52%), Gaps = 61/1044 (5%)
Query: 16 EEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRTM 75
EEKV FW E I++K E R P + F DGPP+ +G H G IKD++ R+ TM
Sbjct: 13 EEKVLTFWKEQNIFQKTLENRDGSPTFSFYDGPPFATGLPHYGHLLAGTIKDVVCRYATM 72
Query: 76 QGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIMTE 135
G+ V R+ G+D HG+P+E +VE++LGL T+ ++ G+ NF ++C++ +
Sbjct: 73 DGHYVPRRFGWDCHGVPVEYEVEKSLGL-TEPGAIDRFGIANFNEECRKIVFRYVDEWKY 131
Query: 136 QFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHE 195
+G W+D+ + T+ ++ES W+ +++GL+ + +V+ + + T L+ E
Sbjct: 132 FVDRIGRWVDFSATWKTMDLSFMESVWWVFHSLYKQGLVYEGTKVVPFSTKLGTPLSNFE 191
Query: 196 VRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVKVKVEFNG 255
YK DPS+ KF ++ + LL WTTTPWTL +N+A++ HP YV+++ + +G
Sbjct: 192 AGQNYKEVDDPSVVAKFALQDDQG-ILLAWTTTPWTLVSNMALAVHPGLTYVRIQDKESG 250
Query: 256 REEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFKEKYEWA 315
EEY + ++L K + + G L G RY + +P ++ +++ A
Sbjct: 251 -EEYILGQESLARWFPDRESYKW--IGQLSGESLVGRRYCPL----FPYFQDQQDR--GA 301
Query: 316 HRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTE--GKWKGIY 373
RVI ADF+ EGTG+VH AP GE DF Q++ +P+ P+D+QG +T + G Y
Sbjct: 302 FRVIPADFIEESEGTGVVHMAPAFGEADFFACQEHNVPLVCPVDNQGCFTSEVTDFVGEY 361
Query: 374 VKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKDKIIKE 433
+K AD I L+ + L G I H+YP CWR +PLI++A + WF+ + KVK K++K
Sbjct: 362 IKFADKGIARRLKNENKLFYQGTIRHRYPFCWRTDSPLIYKAVNSWFVSVEKVKHKMLKA 421
Query: 434 NDEKVTWYPDWVKI-RFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVE 492
N E + W P +K RF + + DW ISR RYWG P+PIW+SEDGE+ V+ S +EL E
Sbjct: 422 N-ESIHWTPGHIKHGRFGKWLEGARDWAISRNRYWGTPIPIWRSEDGELLVIRSIQELEE 480
Query: 493 LAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDV 552
L +G++I DLHR ++D +I NGK R+ V D
Sbjct: 481 L------SGQKI-------------------VDLHRHFIDEIVIHKNGKSFHRIPYVFDC 515
Query: 553 WFDSGIASWASLGYP-RNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVAFDTVPYRR 611
WFDSG +A YP E E +PADFI EG DQ WFY+ + FD ++
Sbjct: 516 WFDSGAMPYAQNHYPFERAEETEARFPADFIAEGLDQTRGWFYTLTVIAAALFDQPAFKN 575
Query: 612 VAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYML-WATNPWENLKFSWKGVE 670
V ++G VL E G+KMSK L N P+++++ G D R Y+L E+L+FS KGVE
Sbjct: 576 VIVNGIVLAEDGNKMSKRLNNYPSPKKIMDTYGADALRLYLLNSVVVKAEDLRFSDKGVE 635
Query: 671 QV-RRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISEVENGI 729
V +++L L N TY L F P + +L E D+WILS + SL+ + +
Sbjct: 636 AVLKQVLLPLSNALAFYKTYAELYGFSPNETT--DLELAEIDRWILSSLYSLVGKTRENM 693
Query: 730 ESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFDVLLRLLA 789
+ L A +F +EDL+ WY+R R+R W + PD+ AA+ TL++V V +++A
Sbjct: 694 AQYDLHAAVSPFIDF-IEDLTNWYIRRSRRRFWESEDSPDRRAAFATLYEVLMVFSKIIA 752
Query: 790 PFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREMEFIRRIVEAGSAARQ 849
PF P+ AE++YQ L R T+ ESVH+ D+P V + I +LE++M+ IR IV G + R+
Sbjct: 753 PFIPFTAEDMYQQL-RVETDPESVHLCDFPHVVLEKILPDLEKKMQDIREIVALGHSLRK 811
Query: 850 RAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQLNAKEVKVGRVERELT---IKPNF 906
K+K+R P++ + I E + A+ +++ ++ ++LN KEV E +KPNF
Sbjct: 812 EHKLKVRQPLQHMYIVGAKERM-AALAQVDSLIGEELNVKEVHFCSETPEYVTTLVKPNF 870
Query: 907 AKLG-------PEFKGDAKIIAKWINENGRELYEKGELTVEIDGKTFHLTREHIIVEEKL 959
LG PE + K +A E + G + + + +T L E I V +
Sbjct: 871 RSLGKRVGNRLPEIQ---KALAGLSQEQIQAFMHNGFMVLSLGEETISLNEEDITVSWEA 927
Query: 960 PDFFVSEEFEGGRVFVDKTLTRELIAEGLAREFVRRIQEMRKRLDLDVNDRIIVTIETTD 1019
FV+ +D LT LI EG+ARE V +I MR+ L V+DRI + +
Sbjct: 928 APGFVARSSASFVAILDCQLTSPLIMEGIAREIVNKINTMRRNGKLHVSDRIAIRLHAPK 987
Query: 1020 ENVELLKENLDYIMRETRADKIVF 1043
E + +YI ET + F
Sbjct: 988 IVQEAFSQYEEYICEETLTTSVSF 1011
>sp|P46213|SYI_THEMA ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|7437563|pir||B72263 isoleucine--tRNA ligase (EC
6.1.1.5) - Thermotoga maritima (strain MSB8)
>gi|4981921|gb|AAD36431.1|AE001790_3 (AE001790)
isoleucyl-tRNA synthetase [Thermotoga maritima]
Length = 919
Score = 573 bits (1461), Expect = e-162
Identities = 328/901 (36%), Positives = 501/901 (55%), Gaps = 84/901 (9%)
Query: 23 WSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRTMQGYNVWR 82
W + ++Y V E RK P + DGPPY +G IH+GTA NKI+KD++++++TM+GY
Sbjct: 31 WEKMDLYNYVLEQRKGKPLFVLHDGPPYANGHIHIGTALNKILKDIVVKYKTMRGYRAPY 90
Query: 83 QPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIMTEQFKMLGI 142
PG+D HGLPIE +V Q LG K K+ +I KKC+EFAL + I E+FK LG+
Sbjct: 91 VPGWDTHGLPIEHRVSQELGEKIKEMSPAEIR-----KKCEEFALRFVDIQREEFKRLGV 145
Query: 143 WMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHEVRGEYKL 202
DW+NPY+T+K +Y K E+G + + + ++WCPRC TALAE E+ EY
Sbjct: 146 RGDWENPYITLKPDYEVKILDVFKTLVEQGNVYRSLKPIYWCPRCRTALAEAEI--EYHD 203
Query: 203 RKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVKVKVEFNGREEYWIL 262
K PSIYVKF + N +++IWTTTPWTLPAN+ ++ HPDY+Y VKV EE W++
Sbjct: 204 HKSPSIYVKFRSKEDPNFFIVIWTTTPWTLPANVGIALHPDYEYSVVKV----GEEKWVI 259
Query: 263 AKALVDKVLGEIGVK-GEVVEEFKGRELEGLRYVHILMDEYPRQKEFKEKYEWAHRVILA 321
A L+D E G+ VVE+ KG++LEG +VH + D+ RVILA
Sbjct: 260 ATDLLDAFSKETGIDCSNVVEKIKGKDLEGKEFVHPIFDDR------------TSRVILA 307
Query: 322 DFVTLEEGTGLVHTAPGHGEEDFEVGQ-KYGLPVYSPLDDQGKYTE--GKWKGIYVKEAD 378
D+V+LE GTG VH APGHGEED+ G +YGLP+ SP+D++G++TE GK+KG+++++A+
Sbjct: 308 DYVSLETGTGCVHIAPGHGEEDYIYGHVQYGLPIVSPVDEEGRFTEEAGKYKGMFIEDAN 367
Query: 379 PKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKI--SKVKDKIIKENDE 436
IIE L+ KG LV A I H YPHCWRCK P+IFRAT+QWF+ + + ++ K+++E D
Sbjct: 368 EVIIEDLKRKGILVHASSITHSYPHCWRCKGPVIFRATEQWFISVDHNNLRQKVLEEID- 426
Query: 437 KVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVELAVA 496
KV W P+W + R + V + DW ISRQR WG P+P AV
Sbjct: 427 KVKWIPEWGRNRIRSMVEERPDWCISRQRVWGTPIP---------------------AVK 465
Query: 497 IEVNGERIELPESYEEKLKVIE------------EKLGPEDLHRPYVDAFIIKVNGKDMR 544
+ GE + P+ E +K++E E+L PED P K +
Sbjct: 466 CKECGEVVLDPKVIEHFMKIVEKEGTNAWFEKEVEELIPEDFVCP-------KCGKRSFE 518
Query: 545 RVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVAF 604
++ D +DVW DSG AS Y K + +P D +EG DQ WF+S ++
Sbjct: 519 KMLDTLDVWIDSG----ASFEYITTKR-EDHPFPLDMYLEGSDQHRGWFHSSIFLAVAKR 573
Query: 605 DTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENLKF 664
+ PY+ V HG++ DE+G KMSKSLGN++ P EVVE+ G + R + L +++ + ++K
Sbjct: 574 GSAPYKEVLTHGFIKDEQGRKMSKSLGNVVDPMEVVEKYGAEILRLW-LASSDYFNDIKI 632
Query: 665 SWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISE 724
S + VEQ + + N + +L++FDP D+W L R+ +I
Sbjct: 633 SMRIVEQQTEVYRKIRNTF--RFLLGNLEDFDPELDRVPHEKLLTIDRWALGRLQEIIKR 690
Query: 725 VENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDP-DKLAAYYTLWKVFDV 783
+S+ +K + + +LS Y+ +++ RL+VE +D + +A + ++
Sbjct: 691 ATEYYDSYEFSKVYNLVVKYCTTELSSLYLDVVKDRLYVEAKDSIYRRSAQTVMHEILIS 750
Query: 784 LLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAID----EELEREMEFIRR 839
L+++LAP + EE+Y +L ++V WP+ E+ ID E+ E+ +
Sbjct: 751 LMKILAPIMTFTMEEVYSHLHEKDRKYKTVQAEYWPEYREEFIDRKLMEDFEKLLSIRED 810
Query: 840 IVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQLNAKEVKVGRVERE 899
+++A RQ+ I +++ +++T+K +E+ IL + +V + E
Sbjct: 811 VLKALEEKRQQDVIGHSLDA-EVVLVPKNDTIKALLEKYRDILEELFIVSKVSLSDASGE 869
Query: 900 L 900
L
Sbjct: 870 L 870
>sp|O83466|SYI_TREPA ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|7437562|pir||E71322 isoleucine--tRNA ligase (EC
6.1.1.5) (ileS) - syphilis spirochete
>gi|3322738|gb|AAC65439.1| (AE001222) isoleucyl-tRNA
synthetase (ileS) [Treponema pallidum]
Length = 1091
Score = 568 bits (1448), Expect = e-160
Identities = 357/1091 (32%), Positives = 560/1091 (50%), Gaps = 95/1091 (8%)
Query: 16 EEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRTM 75
E ++ FW E ++ + R G Y F DGPP+ +G H G IKD+I R++TM
Sbjct: 15 ERRILAFWRERRVFEQSVAQRAQGKSYVFFDGPPFATGLPHFGHFVPSTIKDIIPRYQTM 74
Query: 76 QGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIMTE 135
+G V R+ G+D HGLPIE +EQ L L +K ++ E GV F C+ L +K
Sbjct: 75 RGAYVPRRFGWDCHGLPIEHLIEQELNLNSKSDV-ESYGVSAFNAACRSSVLRYVKEWQR 133
Query: 136 QFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHE 195
LG W+D+DN Y T+ Y+ES W+ + + W++ LL + ++L +CPRC TAL+ HE
Sbjct: 134 TLTRLGRWVDFDNDYKTMDVCYMESVWWVVAQLWQRKLLYEGYKILPYCPRCATALSNHE 193
Query: 196 VR-GEYKLRKDPSIYVKF------PVEGKENEY----------------LLIWTTTPWTL 232
+ G Y+ DP+I V+F P E+ L WTTTPWTL
Sbjct: 194 LNLGGYQDVSDPAITVRFECTSVVPGSPAAREFCAAASWGSASLPAHTCFLAWTTTPWTL 253
Query: 233 PANLAVSAHPDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGL 292
P N A++ P YV ++ +E++ILA++ ++ + VV E +G L G+
Sbjct: 254 PCNAALALGPQILYVLIE----ANDEHYILARSRLEFYYPDSSAY-RVVWEKRGEHLAGI 308
Query: 293 RY----VHILMDEYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQ 348
RY + + + P + E +ADFV+ E+GTG+VH AP GE+D+EV +
Sbjct: 309 RYRPLFSYPVFGQGPDPSVQGDSEEGLFCTRVADFVSTEDGTGVVHVAPAFGEDDYEVFK 368
Query: 349 KYGLPVYSPLDDQGKYTE--GKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWR 406
G+ + PLD + ++T ++G++VK AD II ++++G L + +I H YPHCWR
Sbjct: 369 DAGISIQCPLDAECRFTAEVADYQGLFVKAADKAIIARVQKQGALFRREQISHAYPHCWR 428
Query: 407 CKTPLIFRATDQWFLKISKVKDKIIKENDEKVTWYPDWVKI-RFDNGVRDSGDWVISRQR 465
C +PLI+RA WF+ + K+KDK++ N + W P ++ RF + + DW ISR R
Sbjct: 429 CASPLIYRAVHSWFVAVEKIKDKMLAAN-ASICWQPSHIRDGRFGKWLVCARDWAISRDR 487
Query: 466 YWGIPLPIWQSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPED 525
YWG PLPIW+ A + G R +L YE ++ ED
Sbjct: 488 YWGNPLPIWRCVH---------------CGATDCIGSRTQL---YERSGMLL------ED 523
Query: 526 LHRPYVDAFIIK-VNGKDMRRVKDVVDVWFDSGIASWASLGYP-RNKELFEKLWPADFIV 583
LH+ VD I G MRRV +V+D WF+SG +A YP + FE+ +PA FI
Sbjct: 524 LHKHVVDMVTIPCACGSVMRRVPEVLDCWFESGAMPYAQQHYPFEHATDFERYFPAHFIS 583
Query: 584 EGEDQVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERA 643
EG DQ WFY+ ++ F+ + + G VL G KMSK+L N P EV++R
Sbjct: 584 EGLDQTRGWFYTLTILAVALFERPAFENCIVTGLVLASDGKKMSKALRNYADPNEVMDRY 643
Query: 644 GRDTFRFYML-WATNPWENLKFSWKGVEQVRRMLNI-LWNVYVLASTYMSLDNFDP---- 697
G D R +++ A ++LK+S +GV+ + + + I LWN Y TY ++D DP
Sbjct: 644 GADALRLFLVRSAVVRADDLKYSDEGVKDILKTVIIPLWNSYSFYVTYANIDGIDPPVCA 703
Query: 698 ----------RKLNPDELPFREEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVE 747
R P D+WILS L+ ++ ++++ ++K + ++ V+
Sbjct: 704 KVDGMGQAVTRLATHLNNPL---DRWILSLTEKLVQDIACALDAYDVSKVADPIVSY-VD 759
Query: 748 DLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPF 807
L+ WY+R R+R W D DK AY TL+ V + +AP P+I E I+QN IR
Sbjct: 760 QLNNWYIRRSRRRFWKSINDEDKRCAYNTLYCVLKRCVLAIAPVVPFITESIWQN-IRAA 818
Query: 808 TNVESVHMLDWPKVDEKAIDEELEREMEFIRRIVEAGSAARQRAKIKLRYPVRRIIIETE 867
+V+SVH+ D+P D+ LE +ME ++R+V A R + +K+R P++ + + T
Sbjct: 819 DDVQSVHLADYPVCTPMVRDDALEFKMETVQRVVSMARAIRAQCNLKVRQPLKAMQVITR 878
Query: 868 DETVKKAVERLNRILRDQLNAKEVKVGRVERELT---IKPNFAKLGPEF----KGDAKII 920
+ + A+ + + D+LN KE+ E E+ K NF LG E K A I
Sbjct: 879 NPMERSALLEMEEDVLDELNVKELVFHEKEDEIVEYRAKANFRVLGKELGSKTKRAALSI 938
Query: 921 AKWINENGRELYEKGELTVEIDGKTFHLTREHIIVEEKLPDFFVSEEFEGGRVFVDKTLT 980
+ + +E+ E L +++DG LT E I+V+ + + V +D TLT
Sbjct: 939 ERLSSAEIQEILEGTTLYLDVDGDRLELTEEKILVQRIERESLKAINEGTLTVALDTTLT 998
Query: 981 RELIAEGLAREFVRRIQEMRKRLDLDVNDRIIVTIETTDENVELLKENLD----YIMRET 1036
+L+ EG R+ VR +Q +RK + DRI + + ++D+++ ++ D YI+ ET
Sbjct: 999 EDLLLEGAIRDLVRGVQNLRKERGFSLVDRICLRVFSSDQDIVCARKAYDLHRSYIVGET 1058
Query: 1037 RADKIVFGKAK 1047
A + + + +
Sbjct: 1059 LAAHVQWARVR 1069
>gi|6319395 cytoplasmic isoleucyl-tRNA synthetase; Ils1p [Saccharomyces
cerevisiae] >gi|135134|sp|P09436|SYIC_YEAST
ISOLEUCYL-TRNA SYNTHETASE, CYTOPLASMIC (ISOLEUCINE--TRNA
LIGASE) (ILERS) >gi|68524|pir||SYBYI4 isoleucine--tRNA
ligase (EC 6.1.1.5) - yeast (Saccharomyces cerevisiae)
>gi|3820|emb|CAA30733.1| (X07886) ILSI (AA 1-1072)
[Saccharomyces cerevisiae] >gi|498991|emb|CAA56034.1|
(X79489) ILS1 protein [Saccharomyces cerevisiae]
>gi|536123|emb|CAA84898.1| (Z35838) ORF YBL076c
[Saccharomyces cerevisiae]
Length = 1072
Score = 558 bits (1423), Expect = e-157
Identities = 351/1074 (32%), Positives = 569/1074 (52%), Gaps = 92/1074 (8%)
Query: 14 KLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFR 73
K EEKV W E + + EL KD P++ F DGPP+ +G H G IKD++ R+
Sbjct: 12 KEEEKVLSLWDEIDAFHTSLELTKDKPEFSFFDGPPFATGTPHYGHILASTIKDIVPRYA 71
Query: 74 TMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIM 133
TM G++V R+ G+D HG+PIE +++ LG+ K ++ K G+EN+ +C+ +
Sbjct: 72 TMTGHHVERRFGWDTHGVPIEHIIDKKLGITGKDDVF-KYGLENYNNECRSIVMTYASDW 130
Query: 134 TEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAE 193
+ LG W+D+DN Y T+ ++ES W+ K+ EKG + + +V+ + T L+
Sbjct: 131 RKTIGRLGRWIDFDNDYKTMYPSFMESTWWAFKQLHEKGQVYRGFKVMPYSTGLTTPLSN 190
Query: 194 HEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVKVKVEF 253
E + YK DP++ + F V G+E L+ WTTTPWTLP+NL++ + D++YVK+ E
Sbjct: 191 FEAQQNYKDVNDPAVTIGFNVIGQEKTQLVAWTTTPWTLPSNLSLCVNADFEYVKIYDE- 249
Query: 254 NGREEYWILAKALVDKVLGE-IGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFKEKY 312
R+ Y+IL ++L+ + + K ++VE+ KG +L GL+Y P F E++
Sbjct: 250 -TRDRYFILLESLIKTLYKKPKNEKYKIVEKIKGSDLVGLKY-------EPLFPYFAEQF 301
Query: 313 -EWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGL-----PVYSPLDDQGKYTE 366
E A RVI D+VT + GTG+VH AP GEED K G+ + + +DD G++T+
Sbjct: 302 HETAFRVISDDYVTSDSGTGIVHNAPAFGEEDNAACLKNGVISEDSVLPNAIDDLGRFTK 361
Query: 367 G--KWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKIS 424
++G+YVK+AD II++L G L+ A +I H YP CWR TPL++R+ WF+++
Sbjct: 362 DVPDFEGVYVKDADKLIIKYLTNTGNLLLASQIRHSYPFCWRSDTPLLYRSVPAWFVRVK 421
Query: 425 KVKDKIIKENDEKVTWYPDWVK-IRFDNGVRDSGDWVISRQRYWGIPLPIWQSED-GEIY 482
+ +++ ++ K W P+ +K RF N + ++ DW +SR RYWG P+P+W S+D E+
Sbjct: 422 NIVPQML-DSVMKSHWVPNTIKEKRFANWIANARDWNVSRNRYWGTPIPLWVSDDFEEVV 480
Query: 483 VVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFII--KVNG 540
VGS +EL EL + DLHR +D I K
Sbjct: 481 CVGSIKELEELTGVRNIT------------------------DLHRDVIDKLTIPSKQGK 516
Query: 541 KDMRRVKDVVDVWFDSGIASWASLGYP-RNKELFEKLWPADFIVEGEDQVTKWFYSQQAA 599
D++R+++V D WF+SG +AS YP N E F++ PA+FI EG DQ WFY+
Sbjct: 517 GDLKRIEEVFDCWFESGSMPYASQHYPFENTEKFDERVPANFISEGLDQTRGWFYTLAVL 576
Query: 600 SIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWA-TNP 658
F +VPY+ V + G VL G KMSKSL N P V+ + G D R Y++ +
Sbjct: 577 GTHLFGSVPYKNVIVSGIVLAADGRKMSKSLKNYPDPSIVLNKYGADALRLYLINSPVLK 636
Query: 659 WENLKFSWKGV-EQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREE------- 710
E+LKF +GV E V ++L WN + ++L +K++ + + +
Sbjct: 637 AESLKFKEEGVKEVVSKVLLPWWNSFKFLDGQIAL----LKKMSNIDFQYDDSVKSDNVM 692
Query: 711 DKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDK 770
D+WIL+ + SL+ + + + L L NF +++L+ WY+R R+RL E D
Sbjct: 693 DRWILASMQSLVQFIHEEMGQYKLYTVVPKLLNF-IDELTNWYIRFNRRRLKGENGVEDC 751
Query: 771 LAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNV---------ESVHMLDWPKV 821
L A +L+ +R +APFTP+++E IY L SVH L +P V
Sbjct: 752 LKALNSLFDALFTFVRAMAPFTPFLSESIYLRLKEYIPEAVLAKYGKDGRSVHFLSYPVV 811
Query: 822 DEKAIDEELEREMEFIRRIVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRI 881
++ DE +E + ++ +++ G R++ I L+ P++ ++I DE+ K VE L
Sbjct: 812 KKEYFDEAIETAVSRMQSVIDLGRNIREKKTISLKTPLKTLVILHSDESYLKDVEALKNY 871
Query: 882 LRDQLNAKEVKVGRVERELTIK----PNFAKLGPEFKGDAKIIAKWI----NENGRELYE 933
+ ++LN ++V + E + ++ ++ LG + K DAK + + +E RE E
Sbjct: 872 IIEELNVRDVVITSDEAKYGVEYKAVADWPVLGKKLKKDAKKVKDALPSVTSEQVREYLE 931
Query: 934 KGELTVEIDGKTFHLTREHIIVEEKLPDFFVSEEFEGGR-----VFVDKTLTRELIAEGL 988
G+L E+ G L + + LP+ V E + +D + EL +EGL
Sbjct: 932 SGKL--EVAG--IELVKGDLNAIRGLPESAVQAGQETRTDQDVLIIMDTNIYSELKSEGL 987
Query: 989 AREFVRRIQEMRKRLDLDVNDRIIVTIETTDENVE---LLKENLDYIMRETRAD 1039
ARE V RIQ++RK+ L+ D ++V E + ++ ++KE+ D + + R+D
Sbjct: 988 ARELVNRIQKLRKKCGLEATDDVLVEYELVKDTIDFEAIVKEHFDMLSKTCRSD 1041
>sp|Q9X7E5|SYI_MYCLE ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|4539131|emb|CAB39575.1| (AL049478) putative
isoleucyl-tRNA synthetase [Mycobacterium leprae]
Length = 1059
Score = 553 bits (1410), Expect = e-156
Identities = 353/1082 (32%), Positives = 562/1082 (51%), Gaps = 116/1082 (10%)
Query: 15 LEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRT 74
LE +V +WS ++ +R D P+Y F DGPP+ +G H G +KD++ R+RT
Sbjct: 25 LEAQVLDYWSNDDTFRASIARCDDAPEYVFYDGPPFANGLPHYGHLLTGYVKDIVPRYRT 84
Query: 75 MQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIMT 134
M GY V R+ G+D HGLP E++VE+ LG+ K +I + +G+ F + C++ L +
Sbjct: 85 MCGYKVERRFGWDTHGLPAELEVERQLGITDKSQI-DAMGIAAFNEACRKSVLRYTEEWQ 143
Query: 135 EQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEH 194
W+D+DN Y T+ Y+ES + K+ W+KGL + RVL +C R ET L+ H
Sbjct: 144 AYVTRQARWVDFDNDYKTLDLSYMESVIWAFKQLWDKGLAYESYRVLPYCWRDETPLSNH 203
Query: 195 EVRGE---YKLRKDPSIYVKFPVEGKENE-----YLLIWTTTPWTLPANLAVSAHPDYDY 246
E+R + Y+ R+DP++ + F V G ++E YLL+WTTTPWTLP+NLAV+ HPD Y
Sbjct: 204 ELRMDDDVYQSRQDPAVTLGFKVLGGDDEDLVGAYLLVWTTTPWTLPSNLAVAVHPDVTY 263
Query: 247 VKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQK 306
V V+ + ++LA+A + E+G + EV+ ++G +L G Y+ P +
Sbjct: 264 VDVR----AGDRRFVLAQARLTAYARELGDEPEVLATYRGADLLGRHYL-------PPFQ 312
Query: 307 EFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKY-- 364
F E A +V+ DFVT ++GTG+VH AP +GE+D K G+ +P+D G +
Sbjct: 313 YFYESARNAFQVLPGDFVTTDDGTGIVHIAPAYGEDDMATADKVGIVPVTPVDSNGCFDA 372
Query: 365 TEGKWKGIYVKEADPKIIEHLREK--------GYLVKAGEIEHKYPHCWRCKTPLIFRAT 416
T ++G +V EA+ +II L+ + L++ EH YPHCWRC+ PLI+RA
Sbjct: 373 TVPDYQGQHVFEANAQIIRDLKNQSGSAAVNGAVLLRHETYEHPYPHCWRCRNPLIYRAV 432
Query: 417 DQWFLKISKVKDKIIKENDEKVTWYPDWVKI-RFDNGVRDSGDWVISRQRYWGIPLPIWQ 475
WF+ +++ +D++++ N +++TWYP+ VK +F ++ + DW ISR RYWG P+P+W+
Sbjct: 433 SSWFVAVTEFRDRMVELN-QQITWYPEHVKDGQFGKWLQGARDWSISRNRYWGTPIPVWK 491
Query: 476 SEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFI 535
S+D + I+V G EL + + P +LHRPY+D +
Sbjct: 492 SDDPDY-------------PRIDVYGSLDELERDFGVR---------PTNLHRPYIDE-L 528
Query: 536 IKVNGKD------MRRVKDVVDVWFDSGIASWASLGYP-RNKELFEKL------------ 576
+ N D MRR+ DV DVWFDSG +A + YP N + F+
Sbjct: 529 TRPNPDDPTGLSTMRRIPDVFDVWFDSGSMPYAQVHYPFENDDWFDGFDSADSDKQVDAH 588
Query: 577 WPADFIVEGEDQVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRP 636
+P DFIVE Q WFY+ + FD ++ HG VL G KMSKSL N
Sbjct: 589 YPGDFIVEYIGQARGWFYTLHVLATALFDRPAFKTCIAHGVVLGSNGQKMSKSLRNYPDV 648
Query: 637 EEVVERAGRDTFRFYMLWATNP---WENLKFSWKGV-EQVRRMLNILWNVYVLASTYMSL 692
E+ +R G D R++++ +P NL + G+ E +R++L LWN Y + Y
Sbjct: 649 TEIFDRDGSDAMRWFLM--ASPILRGGNLIITEPGIREGMRQVLLPLWNAYSFLALYA-- 704
Query: 693 DNFDPRKLNPDELPFREEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRW 752
P+ D++IL+++ L ++ +E ++ A L F E L+ W
Sbjct: 705 ----PKIGTWHTDVSHVLDRYILAKLAVLRDDLSQAMEVCDISGACEQLRQF-TEPLTNW 759
Query: 753 YVRLIRKRLWVEGEDPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVES 812
Y+R R R W E D A TL V +V RL AP P I E I+ R T S
Sbjct: 760 YLRRSRARFWDEDVD-----AIDTLHTVLEVTARLAAPLLPLITEIIW----RSVTGGRS 810
Query: 813 VHMLDWPKVDEKAIDEELEREMEFIRRIVEAGSAARQRAKIKLRYPVRRIIIET-EDETV 871
VH+ DWP+ ++ D +L M+ +R++ A S+ R+ K+++R P+ ++++ + +
Sbjct: 811 VHLTDWPQANQLPADPDLVAVMDQVRQVCSAASSLRKAKKLRVRLPLPKLVVAVYNSQRL 870
Query: 872 KKAVERLNRILRDQLNAKEVKV-------GRVERELTIKPNFAKLGPEFKGDAKIIAKWI 924
K ++ ++ D+LN K++++ GR E + + +LG + + K++
Sbjct: 871 KPYID----LIGDELNVKQIELTDAIDTYGRFEFTVNARVAGPRLGRDVQAAIKVVKAGE 926
Query: 925 N-ENGRELYEKGELTVEIDGKTFHLTREHIIVEEKLPDFFVSEEFEGGRVFVDKTLTREL 983
N G + ++ D + L + +LPD G V +D T+T EL
Sbjct: 927 GVANPDGTLTAGPVVLQPDEYSSRLVAANPEFTAELPD-------GSGLVVLDDTVTPEL 979
Query: 984 IAEGLAREFVRRIQEMRKRLDLDVNDRIIVTIETTDENVELLKENLDYIMRETRADKIVF 1043
AEG A++ +R +QE+RK + LDV+DRI V + E + + + D+I RE A F
Sbjct: 980 EAEGWAKDRIRELQELRKLIGLDVSDRIRVLMSVPAERADWARVHRDFIAREILATSFEF 1039
Query: 1044 GK 1045
G+
Sbjct: 1040 GE 1041
>gi|11429025 isoleucine-tRNA synthetase [Homo sapiens]
>gi|730870|sp|P41252|SYI_HUMAN ISOLEUCYL-TRNA SYNTHETASE,
CYTOPLASMIC (ISOLEUCINE--TRNA LIGASE) (ILERS) (IRS)
>gi|2135522|pir||I59314 isoleucine--tRNA ligase (EC
6.1.1.5) - human >gi|551622|dbj|BAA05835.1| (D28473)
isoleucyl-tRNA synthetase [Homo sapiens]
Length = 1266
Score = 553 bits (1410), Expect = e-156
Identities = 352/1071 (32%), Positives = 562/1071 (51%), Gaps = 94/1071 (8%)
Query: 16 EEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRTM 75
EEK+ +FW+E +++ + K PK+ F DGPP+ +G H G IKD++ R+
Sbjct: 19 EEKILEFWTEFNCFQECLKQSKHKPKFTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQ 78
Query: 76 QGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIMTE 135
G++V R+ G+D HGLP+E ++++ LG++ +++ K+G+ + +C+ +
Sbjct: 79 SGFHVDRRFGWDCHGLPVEYEIDKTLGIRGPEDVA-KMGITEYNNQCRAIVMRYSAEWKS 137
Query: 136 QFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHE 195
LG W+D+DN Y T+ +++ES W+ K+ ++KGL+ + +V+ + C T L+ E
Sbjct: 138 TVSRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMPFSTACNTPLSNFE 197
Query: 196 VRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVKVKVEFNG 255
YK +DPS++V FP+E E L+ WTTTPWTLP+NLAV +P+ YVK+K G
Sbjct: 198 SHQNYKDVQDPSVFVTFPLEEDETVSLVAWTTTPWTLPSNLAVCVNPEMQYVKIKDVARG 257
Query: 256 REEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFKEKYEWA 315
R IL +A + L ++ E++E F G L+G +Y L D + + KE A
Sbjct: 258 R--LLILMEARL-SALYKLESDYEILERFPGAYLKGKKY-RPLFDYFLKCKE-----NGA 308
Query: 316 HRVILADFVTLEEGTGLVHTAPGHGEE------DFEVGQKYGLPVYSPLDDQGKYTE--G 367
V++ ++V EEGTG+VH AP G E DF + +K LPV P+D G +T
Sbjct: 309 FTVLVDNYVKEEEGTGVVHQAPYFGAEDYRVCMDFNIIRKDSLPV-CPVDASGCFTTEVT 367
Query: 368 KWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVK 427
+ G YVK+AD II L+E+G L+ A H YP CWR TPLI++A WF+++ +
Sbjct: 368 DFAGQYVKDADKSIIRTLKEQGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRVENMV 427
Query: 428 DKIIKENDEKVTWYPDWVK-IRFDNGVRDSGDWVISRQRYWGIPLPIWQSED-GEIYVVG 485
D++++ ND W P+ V+ RF N ++D+ DW ISR RYWG P+P+W S+D E+ +G
Sbjct: 428 DQLLRNND-LCYWVPELVREKRFGNWLKDARDWTISRNRYWGTPIPLWVSDDFEEVVCIG 486
Query: 486 SWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFII--KVNGKDM 543
S EL EL +G +I DLHR VD I + +
Sbjct: 487 SVAELEEL------SGAKI-------------------SDLHRESVDHLTIPSRCGKGSL 521
Query: 544 RRVKDVVDVWFDSGIASWASLGYP-RNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIV 602
R+ +V D WF+SG +A + YP NK FE +PADFI EG DQ WFY+ +
Sbjct: 522 HRISEVFDCWFESGSMPYAQVHYPFENKREFEDAFPADFIAEGIDQTRGWFYTLLVLATA 581
Query: 603 AFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNP---W 659
F P++ V ++G VL G KMSK N P ++++ G D R Y++ +P
Sbjct: 582 LFGQPPFKNVIVNGLVLASDGQKMSKRKKNYPDPVSIIQKYGADALRLYLI--NSPVVRA 639
Query: 660 ENLKFSWKGVEQVRRMLNILW-NVY-VLASTYMSLDNFDPRKLNPDELPFREE----DKW 713
ENL+F +GV V + + + W N Y L + L + + +E RE D+W
Sbjct: 640 ENLRFKEEGVRDVLKDVLLPWYNAYRFLIQNVLRLQKEEEIEFLYNENTVRESPNITDRW 699
Query: 714 ILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAA 773
ILS + SLI E + ++ L L F V+ L+ WYVR+ R+RL E D + A
Sbjct: 700 ILSFMQSLIGFFETEMAAYRLYTVVPRLVKF-VDILTNWYVRMNRRRLKGENGMEDCVMA 758
Query: 774 YYTLWKVFDVLLRLLAPFTPYIAEEIYQN---LIRPFT----NVESVHMLDWPKVDEKAI 826
TL+ V L RL+AP+TP++ E +YQN LI P + + S+H L P+V E+ I
Sbjct: 759 LETLFSVLLSLCRLMAPYTPFLTELMYQNLKVLIDPVSVQDKDTLSIHYLMLPRVREELI 818
Query: 827 DEELEREMEFIRRIVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQL 886
D++ E + ++ ++E G R R I ++YP++ I++ +D K ++ L + + ++L
Sbjct: 819 DKKTESAVSQMQSVIELGRVIRDRKTIPIKYPLKEIVVIHQDPEALKDIKSLEKYIIEEL 878
Query: 887 NAKEVKVGRVERE----LTIKPNFAKLGPEFKGDAKIIAKWINENGRELYEKGELTVEID 942
N ++V + + + L +P+ LG KG K + I + E E+ + T I
Sbjct: 879 NVRKVTLSTDKNKYGIRLRAEPDHMVLGKRLKGAFKAVMTSIKQLSSEELEQFQKTGTI- 937
Query: 943 GKTFHLTREHIIVEEKLPDFFVSEEFEGGR------------VFVDKTLTRELIAEGLAR 990
+ H + +E + + ++ GG V +D T + ++ EG+AR
Sbjct: 938 -----VVEGHELHDEDIRLMYTFDQATGGTAQFEAHSDAQALVLLDVTPDQSMVDEGMAR 992
Query: 991 EFVRRIQEMRKRLDLDVNDRIIVTIETTDENVEL---LKENLDYIMRETRA 1038
E + RIQ++RK+ +L D I V + E L ++ + ++I +A
Sbjct: 993 EVINRIQKLRKKCNLVPTDEITVYYKAKSEGTYLNSVIESHTEFIFTTIKA 1043
>gi|4504555 isoleucine-tRNA synthetase [Homo sapiens]
>gi|7770072|ref|NP_038203.1| isoleucine-tRNA synthetase
[Homo sapiens] >gi|440799|gb|AAA80153.1| (U04953)
isoleucyl-tRNA synthetase [Homo sapiens]
Length = 1262
Score = 553 bits (1410), Expect = e-156
Identities = 352/1071 (32%), Positives = 562/1071 (51%), Gaps = 94/1071 (8%)
Query: 16 EEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRTM 75
EEK+ +FW+E +++ + K PK+ F DGPP+ +G H G IKD++ R+
Sbjct: 15 EEKILEFWTEFNCFQECLKQSKHKPKFTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQ 74
Query: 76 QGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIMTE 135
G++V R+ G+D HGLP+E ++++ LG++ +++ K+G+ + +C+ +
Sbjct: 75 SGFHVDRRFGWDCHGLPVEYEIDKTLGIRGPEDVA-KMGITEYNNQCRAIVMRYSAEWKS 133
Query: 136 QFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHE 195
LG W+D+DN Y T+ +++ES W+ K+ ++KGL+ + +V+ + C T L+ E
Sbjct: 134 TVSRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMPFSTACNTPLSNFE 193
Query: 196 VRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVKVKVEFNG 255
YK +DPS++V FP+E E L+ WTTTPWTLP+NLAV +P+ YVK+K G
Sbjct: 194 SHQNYKDVQDPSVFVTFPLEEDETVSLVAWTTTPWTLPSNLAVCVNPEMQYVKIKDVARG 253
Query: 256 REEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFKEKYEWA 315
R IL +A + L ++ E++E F G L+G +Y L D + + KE A
Sbjct: 254 R--LLILMEARL-SALYKLESDYEILERFPGAYLKGKKY-RPLFDYFLKCKE-----NGA 304
Query: 316 HRVILADFVTLEEGTGLVHTAPGHGEE------DFEVGQKYGLPVYSPLDDQGKYTE--G 367
V++ ++V EEGTG+VH AP G E DF + +K LPV P+D G +T
Sbjct: 305 FTVLVDNYVKEEEGTGVVHQAPYFGAEDYRVCMDFNIIRKDSLPV-CPVDASGCFTTEVT 363
Query: 368 KWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVK 427
+ G YVK+AD II L+E+G L+ A H YP CWR TPLI++A WF+++ +
Sbjct: 364 DFAGQYVKDADKSIIRTLKEQGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRVENMV 423
Query: 428 DKIIKENDEKVTWYPDWVK-IRFDNGVRDSGDWVISRQRYWGIPLPIWQSED-GEIYVVG 485
D++++ ND W P+ V+ RF N ++D+ DW ISR RYWG P+P+W S+D E+ +G
Sbjct: 424 DQLLRNND-LCYWVPELVREKRFGNWLKDARDWTISRNRYWGTPIPLWVSDDFEEVVCIG 482
Query: 486 SWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFII--KVNGKDM 543
S EL EL +G +I DLHR VD I + +
Sbjct: 483 SVAELEEL------SGAKI-------------------SDLHRESVDHLTIPSRCGKGSL 517
Query: 544 RRVKDVVDVWFDSGIASWASLGYP-RNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIV 602
R+ +V D WF+SG +A + YP NK FE +PADFI EG DQ WFY+ +
Sbjct: 518 HRISEVFDCWFESGSMPYAQVHYPFENKREFEDAFPADFIAEGIDQTRGWFYTLLVLATA 577
Query: 603 AFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNP---W 659
F P++ V ++G VL G KMSK N P ++++ G D R Y++ +P
Sbjct: 578 LFGQPPFKNVIVNGLVLASDGQKMSKRKKNYPDPVSIIQKYGADALRLYLI--NSPVVRA 635
Query: 660 ENLKFSWKGVEQVRRMLNILW-NVY-VLASTYMSLDNFDPRKLNPDELPFREE----DKW 713
ENL+F +GV V + + + W N Y L + L + + +E RE D+W
Sbjct: 636 ENLRFKEEGVRDVLKDVLLPWYNAYRFLIQNVLRLQKEEEIEFLYNENTVRESPNITDRW 695
Query: 714 ILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAA 773
ILS + SLI E + ++ L L F V+ L+ WYVR+ R+RL E D + A
Sbjct: 696 ILSFMQSLIGFFETEMAAYRLYTVVPRLVKF-VDILTNWYVRMNRRRLKGENGMEDCVMA 754
Query: 774 YYTLWKVFDVLLRLLAPFTPYIAEEIYQN---LIRPFT----NVESVHMLDWPKVDEKAI 826
TL+ V L RL+AP+TP++ E +YQN LI P + + S+H L P+V E+ I
Sbjct: 755 LETLFSVLLSLCRLIAPYTPFLTELMYQNLKVLIDPVSVQDKDTLSIHYLMLPRVREELI 814
Query: 827 DEELEREMEFIRRIVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQL 886
D++ E + ++ ++E G R R I ++YP++ I++ +D K ++ L + + ++L
Sbjct: 815 DKKTESAVSQMQSVIELGRVIRDRKTIPIKYPLKEIVVIHQDPEALKDIKSLEKYIIEEL 874
Query: 887 NAKEVKVGRVERE----LTIKPNFAKLGPEFKGDAKIIAKWINENGRELYEKGELTVEID 942
N ++V + + + L +P+ LG KG K + I + E E+ + T I
Sbjct: 875 NVRKVTLSTDKNKYGIRLRAEPDHMVLGKRLKGAFKAVMTSIKQLSSEELEQFQKTGTI- 933
Query: 943 GKTFHLTREHIIVEEKLPDFFVSEEFEGGR------------VFVDKTLTRELIAEGLAR 990
+ H + +E + + ++ GG V +D T + ++ EG+AR
Sbjct: 934 -----VVEGHELHDEDIRLMYTFDQATGGTAQFEAHSDAQALVLLDVTPDQSMVDEGMAR 988
Query: 991 EFVRRIQEMRKRLDLDVNDRIIVTIETTDENVEL---LKENLDYIMRETRA 1038
E + RIQ++RK+ +L D I V + E L ++ + ++I +A
Sbjct: 989 EVINRIQKLRKKCNLVPTDEITVYYKAKSEGTYLNSVIESHTEFIFTTIKA 1039
>gi|11429023 isoleucine-tRNA synthetase [Homo sapiens]
Length = 1262
Score = 553 bits (1410), Expect = e-156
Identities = 352/1071 (32%), Positives = 562/1071 (51%), Gaps = 94/1071 (8%)
Query: 16 EEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRTM 75
EEK+ +FW+E +++ + K PK+ F DGPP+ +G H G IKD++ R+
Sbjct: 15 EEKILEFWTEFNCFQECLKQSKHKPKFTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQ 74
Query: 76 QGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIMTE 135
G++V R+ G+D HGLP+E ++++ LG++ +++ K+G+ + +C+ +
Sbjct: 75 SGFHVDRRFGWDCHGLPVEYEIDKTLGIRGPEDVA-KMGITEYNNQCRAIVMRYSAEWKS 133
Query: 136 QFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHE 195
LG W+D+DN Y T+ +++ES W+ K+ ++KGL+ + +V+ + C T L+ E
Sbjct: 134 TVSRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMPFSTACNTPLSNFE 193
Query: 196 VRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVKVKVEFNG 255
YK +DPS++V FP+E E L+ WTTTPWTLP+NLAV +P+ YVK+K G
Sbjct: 194 SHQNYKDVQDPSVFVTFPLEEDETVSLVAWTTTPWTLPSNLAVCVNPEMQYVKIKDVARG 253
Query: 256 REEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFKEKYEWA 315
R IL +A + L ++ E++E F G L+G +Y L D + + KE A
Sbjct: 254 R--LLILMEARL-SALYKLESDYEILERFPGAYLKGKKY-RPLFDYFLKCKE-----NGA 304
Query: 316 HRVILADFVTLEEGTGLVHTAPGHGEE------DFEVGQKYGLPVYSPLDDQGKYTE--G 367
V++ ++V EEGTG+VH AP G E DF + +K LPV P+D G +T
Sbjct: 305 FTVLVDNYVKEEEGTGVVHQAPYFGAEDYRVCMDFNIIRKDSLPV-CPVDASGCFTTEVT 363
Query: 368 KWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVK 427
+ G YVK+AD II L+E+G L+ A H YP CWR TPLI++A WF+++ +
Sbjct: 364 DFAGQYVKDADKSIIRTLKEQGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRVENMV 423
Query: 428 DKIIKENDEKVTWYPDWVK-IRFDNGVRDSGDWVISRQRYWGIPLPIWQSED-GEIYVVG 485
D++++ ND W P+ V+ RF N ++D+ DW ISR RYWG P+P+W S+D E+ +G
Sbjct: 424 DQLLRNND-LCYWVPELVREKRFGNWLKDARDWTISRNRYWGTPIPLWVSDDFEEVVCIG 482
Query: 486 SWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFII--KVNGKDM 543
S EL EL +G +I DLHR VD I + +
Sbjct: 483 SVAELEEL------SGAKI-------------------SDLHRESVDHLTIPSRCGKGSL 517
Query: 544 RRVKDVVDVWFDSGIASWASLGYP-RNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIV 602
R+ +V D WF+SG +A + YP NK FE +PADFI EG DQ WFY+ +
Sbjct: 518 HRISEVFDCWFESGSMPYAQVHYPFENKREFEDAFPADFIAEGIDQTRGWFYTLLVLATA 577
Query: 603 AFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNP---W 659
F P++ V ++G VL G KMSK N P ++++ G D R Y++ +P
Sbjct: 578 LFGQPPFKNVIVNGLVLASDGQKMSKRKKNYPDPVSIIQKYGADALRLYLI--NSPVVRA 635
Query: 660 ENLKFSWKGVEQVRRMLNILW-NVY-VLASTYMSLDNFDPRKLNPDELPFREE----DKW 713
ENL+F +GV V + + + W N Y L + L + + +E RE D+W
Sbjct: 636 ENLRFKEEGVRDVLKDVLLPWYNAYRFLIQNVLRLQKEEEIEFLYNENTVRESPNITDRW 695
Query: 714 ILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAA 773
ILS + SLI E + ++ L L F V+ L+ WYVR+ R+RL E D + A
Sbjct: 696 ILSFMQSLIGFFETEMAAYRLYTVVPRLVKF-VDILTNWYVRMNRRRLKGENGMEDCVMA 754
Query: 774 YYTLWKVFDVLLRLLAPFTPYIAEEIYQN---LIRPFT----NVESVHMLDWPKVDEKAI 826
TL+ V L RL+AP+TP++ E +YQN LI P + + S+H L P+V E+ I
Sbjct: 755 LETLFSVLLSLCRLMAPYTPFLTELMYQNLKVLIDPVSVQDKDTLSIHYLMLPRVREELI 814
Query: 827 DEELEREMEFIRRIVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQL 886
D++ E + ++ ++E G R R I ++YP++ I++ +D K ++ L + + ++L
Sbjct: 815 DKKTESAVSQMQSVIELGRVIRDRKTIPIKYPLKEIVVIHQDPEALKDIKSLEKYIIEEL 874
Query: 887 NAKEVKVGRVERE----LTIKPNFAKLGPEFKGDAKIIAKWINENGRELYEKGELTVEID 942
N ++V + + + L +P+ LG KG K + I + E E+ + T I
Sbjct: 875 NVRKVTLSTDKNKYGIRLRAEPDHMVLGKRLKGAFKAVMTSIKQLSSEELEQFQKTGTI- 933
Query: 943 GKTFHLTREHIIVEEKLPDFFVSEEFEGGR------------VFVDKTLTRELIAEGLAR 990
+ H + +E + + ++ GG V +D T + ++ EG+AR
Sbjct: 934 -----VVEGHELHDEDIRLMYTFDQATGGTAQFEAHSDAQALVLLDVTPDQSMVDEGMAR 988
Query: 991 EFVRRIQEMRKRLDLDVNDRIIVTIETTDENVEL---LKENLDYIMRETRA 1038
E + RIQ++RK+ +L D I V + E L ++ + ++I +A
Sbjct: 989 EVINRIQKLRKKCNLVPTDEITVYYKAKSEGTYLNSVIESHTEFIFTTIKA 1039
>sp|Q10765|SYI_MYCTU ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|7437561|pir||E70760 probable ileS protein -
Mycobacterium tuberculosis (strain H37RV)
>gi|1403506|emb|CAA98326.1| (Z74020) ileS [Mycobacterium
tuberculosis]
Length = 1041
Score = 549 bits (1400), Expect = e-155
Identities = 358/1076 (33%), Positives = 552/1076 (51%), Gaps = 112/1076 (10%)
Query: 11 DPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMII 70
D LE +V +WS ++ +R R P+Y F DGPP+ +G H G +KD++
Sbjct: 15 DLPALELEVLDYWSRDDTFRASIARRDGAPEYVFYDGPPFANGLPHYGHLLTGYVKDIVP 74
Query: 71 RFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNL 130
R+RTM+GY V R+ G+D HGLP E++VE+ LG+ K +I E +G+ F C+ L
Sbjct: 75 RYRTMRGYKVERRFGWDTHGLPAELEVERQLGITDKSQI-EAMGIAAFNDACRASVLRYT 133
Query: 131 KIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETA 190
W+D+DN Y T+ Y+ES + K+ W+KGL + RVL +C R ET
Sbjct: 134 DEWQAYVTRQARWVDFDNDYKTLDLAYMESVIWAFKQLWDKGLAYEGYRVLPYCWRDETP 193
Query: 191 LAEHEVRGE---YKLRKDPSIYVKF------PVEGKENEYLLIWTTTPWTLPANLAVSAH 241
L+ HE+R + Y+ R+DP++ V F P G + YLL+WTTTPWTLP+NLAV+
Sbjct: 194 LSNHELRMDDDVYQSRQDPAVTVGFKVVGGQPDNGLDGAYLLVWTTTPWTLPSNLAVAVS 253
Query: 242 PDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDE 301
PD YV+V+ + ++LA+A + E+G + V+ ++G EL G RY+
Sbjct: 254 PDITYVQVQ----AGDRRFVLAEARLAAYARELGEEPVVLGTYRGAELLGTRYL------ 303
Query: 302 YPRQKEFKEKYEW--AHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLD 359
F +W A +V+ DFVT ++GTG+VH AP +GE+D V + G+ +P+D
Sbjct: 304 ----PPFAYFMDWPNAFQVLAGDFVTTDDGTGIVHMAPAYGEDDMVVAEAVGIAPVTPVD 359
Query: 360 DQGKY--TEGKWKGIYVKEADPKIIEHLREKG--------YLVKAGEIEHKYPHCWRCKT 409
+G++ T ++G +V +A+ +I+ L+ + L++ EH YPHCWRC+
Sbjct: 360 SKGRFDVTVADYQGQHVFDANAQIVRDLKTQSGPAAVNGPVLIRHETYEHPYPHCWRCRN 419
Query: 410 PLIFRATDQWFLKISKVKDKIIKENDEKVTWYPDWVKI-RFDNGVRDSGDWVISRQRYWG 468
PLI+R+ WF++++ +D++++ N +++TWYP+ VK +F ++ + DW ISR RYWG
Sbjct: 420 PLIYRSVSSWFVRVTDFRDRMVELN-QQITWYPEHVKDGQFGKWLQGARDWSISRNRYWG 478
Query: 469 IPLPIWQSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHR 528
P+P+W+S+D I+V G EL + + P +LHR
Sbjct: 479 TPIPVWKSDD-------------PAYPRIDVYGSLDELERDFGVR---------PANLHR 516
Query: 529 PYVDAFIIKVNGKD------MRRVKDVVDVWFDSGIASWASLGYP-RNKELFEKLWPADF 581
PY+D + + N D MRR+ DV+DVWFDSG +A + YP N + F+ +P DF
Sbjct: 517 PYIDE-LTRPNPDDPTGRSTMRRIPDVLDVWFDSGSMPYAQVHYPFENLDWFQGHYPGDF 575
Query: 582 IVEGEDQVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVE 641
IVE Q WFY+ + FD ++ HG VL G KMSKSL N EV +
Sbjct: 576 IVEYIGQTRGWFYTLHVLATALFDRPAFKTCVAHGIVLGFDGQKMSKSLRNYPDVTEVFD 635
Query: 642 RAGRDTFRFYMLWATNP---WENLKFSWKGV-EQVRRMLNILWNVYVLASTYMSLDNFDP 697
R G D R++++ +P NL + +G+ + VR++L LWN Y + Y P
Sbjct: 636 RDGSDAMRWFLM--ASPILRGGNLIVTEQGIRDGVRQVLLPLWNTYSFLALYA------P 687
Query: 698 RKLNPDELPFREEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLI 757
+ D++IL+++ L ++ +E + + A L F E L+ WYVR
Sbjct: 688 KVGTWRVDSVHVLDRYILAKLAVLRDDLSESMEVYDIPGACEHLRQF-TEALTNWYVRRS 746
Query: 758 RKRLWVEGEDPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLD 817
R R W E D A TL V +V RL AP P I E I++ L T SVH+ D
Sbjct: 747 RSRFWAEDAD-----AIDTLHTVLEVTTRLAAPLLPLITEIIWRGL----TRERSVHLTD 797
Query: 818 WPKVDEKAIDEELEREMEFIRRIVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVER 877
WP D D +L M+ +R + A S+ R+ K+++R P+ ++I+ E+ + +
Sbjct: 798 WPAPDLLPSDADLVAAMDQVRDVCSAASSLRKAKKLRVRLPLPKLIVAVENPQLLRPFVD 857
Query: 878 LNRILRDQLNAKEVKV-------GRVERELTIKPNFAKLGPEFKGDAKIIAKW---INEN 927
L + D+LN K+V++ GR E + + +LG + + K + IN +
Sbjct: 858 L---IGDELNVKQVELTDAIDTYGRFELTVNARVAGPRLGKDVQAAIKAVKAGDGVINPD 914
Query: 928 GRELYEKGELTVEIDGKTFHLTREHIIVEEKLPDFFVSEEFEGGRVFVDKTLTRELIAEG 987
G L G + D L LPD G V +D T+T EL AEG
Sbjct: 915 GTLL--AGPAVLTPDEYNSRLVAADPESTAALPD-------GAGLVVLDGTVTAELEAEG 965
Query: 988 LAREFVRRIQEMRKRLDLDVNDRIIVTIETTDENVELLKENLDYIMRETRADKIVF 1043
A++ +R +QE+RK LDV+DRI V + E + + + D I E A F
Sbjct: 966 WAKDRIRELQELRKSTGLDVSDRIRVVMSVPAEREDWARTHRDLIAGEILATDFEF 1021
>gb|AAA34712.1| (M19992) isoleucyl-tRNA synthetase (EC 6.1.1.5) [Saccharomyces
cerevisiae]
Length = 1073
Score = 549 bits (1399), Expect = e-155
Identities = 351/1075 (32%), Positives = 568/1075 (52%), Gaps = 93/1075 (8%)
Query: 14 KLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFR 73
K EEKV W E + + EL KD P++ F DGPP+ +G H G IKD++ R+
Sbjct: 12 KEEEKVLSLWDEIDAFHTSLELTKDKPEFSFFDGPPFATGTPHYGHILASTIKDIVPRYA 71
Query: 74 TMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIM 133
TM G++V R+ G+D HG+PIE +++ LG+ K ++ K G+EN+ +C+ +
Sbjct: 72 TMTGHHVERRFGWDTHGVPIEHIIDKKLGITGKDDVF-KYGLENYNNECRSIVMTYASDW 130
Query: 134 TEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAE 193
+ LG W+D+DN Y T+ ++ES W+ K+ EKG + + +V+ + T L+
Sbjct: 131 RKTIGRLGRWIDFDNDYKTMYPSFMESTWWAFKQLHEKGQVYRGFKVMPYSTGLTTPLSN 190
Query: 194 HEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVKVKVEF 253
E + YK DP++ + F V G+E L+ WTTTPWTLP+NL++ + D++YVK+ E
Sbjct: 191 FEAQQNYKDVNDPAVTIGFNVIGQEKTQLVAWTTTPWTLPSNLSLCVNADFEYVKIYDE- 249
Query: 254 NGREEYWILAKALVDKVLGE-IGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFKEKY 312
R+ Y+IL ++L+ + + K ++VE+ KG +L GL+Y P F E++
Sbjct: 250 -TRDRYFILLESLIKTLYKKPKNEKYKIVEKIKGSDLVGLKY-------EPLFPYFAEQF 301
Query: 313 -EWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGL-----PVYSPLDDQGKYTE 366
E A RVI D+VT + GTG+VH AP GEED K G+ + + +DD G++T+
Sbjct: 302 HETAFRVISDDYVTSDSGTGIVHNAPAFGEEDNAACLKNGVISEDSVLPNAIDDLGRFTK 361
Query: 367 G--KWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKIS 424
++G+YVK+AD II++L G L+ A +I H YP CWR TPL++R+ WF+++
Sbjct: 362 DVPDFEGVYVKDADKLIIKYLTNTGNLLLASQIRHSYPFCWRSDTPLLYRSVPAWFVRVK 421
Query: 425 KVKDKIIKENDEKVTWYPDWVK-IRFDNGVRDSGDWVISRQRYWGIPLPIWQSED-GEIY 482
+ +++ ++ K W P+ +K RF N + ++ DW +SR RYWG P+P+W S+D E+
Sbjct: 422 NIVPQML-DSVMKSHWVPNTIKEKRFANWIANARDWNVSRNRYWGTPIPLWVSDDFEEVV 480
Query: 483 VVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFII--KVNG 540
VGS +EL EL + DLHR +D I K
Sbjct: 481 CVGSIKELEELTGVRNIT------------------------DLHRDVIDKLTIPSKQGK 516
Query: 541 KDMRRVKDVVDVWFDSGIASWASLGYP-RNKELFEKLWPADFIVEGEDQVTKWFYSQQAA 599
D++R+++V D WF+SG +AS YP N E FE+ PA+FI EG DQ WFY+
Sbjct: 517 GDLKRIEEVFDCWFESGSMPYASQHYPFENTEKFEERVPANFISEGLDQTRGWFYTLAVL 576
Query: 600 SIVAFDTVPYRR-VAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWA-TN 657
F +VPY++ V + G VL G KMSKSL N P V+ + G D R Y++ +
Sbjct: 577 GTHLFGSVPYKKSVIVSGIVLAADGRKMSKSLKNYPDPSIVLNKYGADALRLYLINSPVL 636
Query: 658 PWENLKFSWKGV-EQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDK---- 712
E+LKF +GV E V ++L WN + ++L +K++ + + + K
Sbjct: 637 KAESLKFKEEGVKEVVSKVLLPWWNSFKFLDGQIAL----LKKMSNIDFQYDDSVKSDNV 692
Query: 713 ---WILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPD 769
IL+ + SL+ + + + L L NF +++L+ WY+R R+RL E D
Sbjct: 693 MAEMILASMQSLVQVIHEEMGQYKLYTVVPKLLNF-IDELTNWYIRFNRRRLKGENVVED 751
Query: 770 KLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNV---------ESVHMLDWPK 820
L A +L+ +R +APFTP+++E IY L SVH L +P
Sbjct: 752 CLKALNSLFDALFTFVRAMAPFTPFLSESIYLRLKEYIPEAVLAKYGKDGRSVHFLSYPV 811
Query: 821 VDEKAIDEELEREMEFIRRIVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNR 880
V ++ DE +E + ++ +++ G R++ I L+ P++ ++I DE+ K VE L
Sbjct: 812 VKKEYFDEAIETAVSRMQSVIDLGRNIREKKTISLKTPLKTLVILHSDESYLKDVEALKN 871
Query: 881 ILRDQLNAKEVKVGRVERELTIK----PNFAKLGPEFKGDAKIIAKWI----NENGRELY 932
+ ++LN ++V + E + ++ ++ LG + K DAK + + +E RE
Sbjct: 872 YIIEELNVRDVVITSDEAKYGVEYKAVADWPVLGKKLKKDAKKVKDALPSVTSEQVREYL 931
Query: 933 EKGELTVEIDGKTFHLTREHIIVEEKLPDFFVSEEFEGGR-----VFVDKTLTRELIAEG 987
E G+L E+ G L + + LP+ V E + +D + EL +EG
Sbjct: 932 ESGKL--EVAG--IELVKGDLNAIRGLPESAVQAGQETRTDQDVLIIMDTNIYSELKSEG 987
Query: 988 LAREFVRRIQEMRKRLDLDVNDRIIVTIETTDENVE---LLKENLDYIMRETRAD 1039
LARE V RIQ++RK+ L+ D ++V E + ++ ++KE+ D + + R+D
Sbjct: 988 LARELVNRIQKLRKKCGLEATDDVLVEYELVKDTIDFEAIVKEHFDMLSKTCRSD 1042
>sp|Q21926|SYI_CAEEL PROBABLE ISOLEUCYL-TRNA SYNTHETASE, CYTOPLASMIC (ISOLEUCINE--TRNA
LIGASE) (ILERS) >gi|7506619|pir||T24176 hypothetical
protein R11A8.6 - Caenorhabditis elegans
>gi|3879120|emb|CAA94369.1| (Z70310) predicted using
Genefinder~Similarity to Human isoleucyl-tRNA synthetase
(SW:SYI_HUMAN), contains similarity to Pfam domain:
PF00133 (tRNA synthetases class I (I, L, M and V)),
Score=1059.9, E-value=0, N=1~cDNA EST yk26b10.3 comes
from this ge>
Length = 1141
Score = 535 bits (1363), Expect = e-150
Identities = 348/1047 (33%), Positives = 549/1047 (52%), Gaps = 83/1047 (7%)
Query: 16 EEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRTM 75
E+KV + W + +++ EL KD P + F DGPP+ +G H G IKD++ R+
Sbjct: 17 EDKVAQKWQDENTFQRSVELSKDRPHFTFYDGPPFATGLPHYGHMLTSTIKDVVGRWAHQ 76
Query: 76 QGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIMTE 135
G+ V R+ G+D HGLP+E ++++ LG+ +++ K+G+ N+ +C++ + +
Sbjct: 77 NGHYVERRFGWDTHGLPVEYEIDKTLGISGPQDVM-KMGIANYNNECRKIVMRYSGEWEK 135
Query: 136 QFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHE 195
LG W+D+ + Y T+ ++ES W+ +KGL+ K +V+ + C T L+ E
Sbjct: 136 TMGRLGRWVDFKHDYKTLYPWFMESVWWAFSELHKKGLVYKGVKVMPFSTACSTPLSNFE 195
Query: 196 VRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVKVKVEFNG 255
YK DP+++V F + N L+ WTTTPWTLP+NLA+ HPD YV K + G
Sbjct: 196 AGQNYKDVVDPAVFVGFKLLDCPNRQLVAWTTTPWTLPSNLALVVHPDMLYVVTKDKTTG 255
Query: 256 REEYWILAKALVDKVLGEIGVKG-EVVEEFKGRELEGLRYVHILMDEYPRQKEFKEKYEW 314
E ++++ LGE+ EV+E+ G +L+ LRY + +P +E+
Sbjct: 256 IE------YVVLEERLGELKNDNLEVIEKLAGSQLKDLRYEPL----FPYFAYMREERN- 304
Query: 315 AHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGL-----PVYSPLDDQGKYTE--G 367
A RV+ FVT + GTG+VH AP GE DF+V G+ + P+D+ GKYT
Sbjct: 305 AFRVLNDTFVTSDSGTGVVHQAPYFGEIDFQVCVANGVIAKDQKMICPVDESGKYTSEVP 364
Query: 368 KWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVK 427
++G+YVK+AD II+ L+E G LV+ E++H YP CWR TPL+++A WF+ + +
Sbjct: 365 DYQGVYVKDADKLIIKRLKEMGNLVRQAEVKHSYPFCWRSDTPLLYKAVPSWFINVETLI 424
Query: 428 DKIIKENDEKVTWYPDWVK-IRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDG-EIYVVG 485
+++ NDE W P +VK RF N +RD+ DW +SR R+WG P+ +W SEDG E+ VG
Sbjct: 425 PRLLANNDE-TYWVPAFVKEKRFANWLRDARDWAVSRNRFWGTPINLWVSEDGEEVVCVG 483
Query: 486 SWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFII-KVNGKD-M 543
S EL EL +G++I DLHR VD I +G+ +
Sbjct: 484 SIAELEEL------SGQKI-------------------TDLHRESVDDVTIPSRSGRGVL 518
Query: 544 RRVKDVVDVWFDSGIASWASLGYP-RNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIV 602
+RV +V D WF+SG +A YP N+++FE +PADFI EG DQ WFY+ S
Sbjct: 519 KRVSEVFDCWFESGSMPYAQNHYPFENRKIFEDNFPADFIAEGIDQTRGWFYTLLVLSTA 578
Query: 603 AFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNP---W 659
F+ P++ + +G VL G KMSKS N P +V + G D R Y++ +P
Sbjct: 579 LFNKPPFKNLICNGLVLASDGAKMSKSKKNYPDPMLIVNKYGADALRLYLI--NSPVVRG 636
Query: 660 ENLKFSWKGVEQVRRMLNILW-NVY------VLASTYMSLDNFDPRKLNPDELPFREEDK 712
ENL+F +GV + + + + W N Y V A + + + FD +N D+
Sbjct: 637 ENLRFREEGVRDLLKDVFLPWFNAYRFFVQNVQAYEHETGNVFD---MNVHVASENVMDR 693
Query: 713 WILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLA 772
WI S NSL++ V ++S+ L L F + L+ Y+RL RKR+ + ++
Sbjct: 694 WIESFTNSLVAFVRKEMDSYRLYAVVGPLTKF-FDTLTNIYIRLNRKRVKGDNGLHEQHH 752
Query: 773 AYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPF-TNVESVHMLDWPKVDEKAIDEELE 831
A L +V +++RL+APFTP+ E I+ NL + + ESVH L PK DE IDE +E
Sbjct: 753 ALAALGRVLILIVRLMAPFTPFFCEYIWLNLKKVIGSTEESVHFLMLPKPDESLIDETVE 812
Query: 832 REMEFIRRIVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQLNAKEV 891
R +E +R +++ R R + ++YP++ +I+ D + V+ L + +LN +++
Sbjct: 813 RRVEVMRNVIDLVRLVRDREGLAVKYPLKEMIVINRDSQFLEDVKSLESYILLELNVRKL 872
Query: 892 KVGRVERE----LTIKPNFAKLGPEFKGDAKIIAKWINENGRELYEKGELTVEIDGKTFH 947
V + +++ L +PNF LG KG+ K +A ++ ++ E ++GK
Sbjct: 873 TVSQDKQKYGITLKAEPNFKILGARLKGEQKKVADYLK---NQITESELEKFLLEGKLTV 929
Query: 948 LTREHIIVEEKLPDFFVSEEFEGGR--------VFVDKTLTRELIAEGLAREFVRRIQEM 999
L E E + S++ G + V +D T LI EGL RE R+Q +
Sbjct: 930 LGHELSSEEVAVSYAAGSDQGHGYKTHSDAKTIVMIDTTEDESLIEEGLCREVTNRVQRL 989
Query: 1000 RKRLDLDVNDRIIVTIETTDENVELLK 1026
RK+ L D V I + + +L K
Sbjct: 990 RKQAKLVSTDTAHVHIVVSPADSQLAK 1016
>sp|O13651|SYIC_SCHPO ISOLEUCYL-TRNA SYNTHETASE, CYTOPLASMIC (ISOLEUCINE--TRNA LIGASE)
(ILERS) >gi|7492116|pir||T40751 isoleucyl-trna
synthetase, cytoplasmic - fission yeast
(Schizosaccharomyces pombe) >gi|2257546|dbj|BAA21439.1|
(AB004538) ISOLEUCYL-TRNA SYNTHETASE ,CYTOPLASMIC
[Schizosaccharomyces pombe] >gi|2950493|emb|CAA17821.1|
(AL022072) isoleucyl-trna synthetase, cytoplasmic
[Schizosaccharomyces pombe]
Length = 1064
Score = 526 bits (1341), Expect = e-148
Identities = 332/1050 (31%), Positives = 543/1050 (51%), Gaps = 73/1050 (6%)
Query: 10 YDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMI 69
++ K EEK+ +FW E + + +L + P Y F DGPP+ +G H G IKD +
Sbjct: 3 FNVPKEEEKIVEFWREIDAFHTQLKLSQGRPTYTFFDGPPFATGRPHHGHLLASTIKDSV 62
Query: 70 IRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNN 129
R+ ++GY+V R+ G+D HGLP+E ++++ LG+ ++ +G++ + +C++ +
Sbjct: 63 TRYACLKGYHVERRFGWDTHGLPVEHEIDKKLGITGSDDVMA-MGIDKYNAECRKIVMTY 121
Query: 130 LKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCET 189
+ LG W+D+DN Y T+ ++ES W+ K KG + + RV+ + C T
Sbjct: 122 ASEWRATVERLGRWIDFDNDYKTLYPSFMESVWWVFKELHTKGKVYRGYRVMPYSTACTT 181
Query: 190 ALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVKV 249
L+ E + YK DP+I V F L WTTTPWTLP+NLA++ HPD Y+K+
Sbjct: 182 PLSNFEAQQNYKEVPDPAIVVAFQSISDPEVSFLAWTTTPWTLPSNLALAVHPDLQYIKI 241
Query: 250 KVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFK 309
++ + ++Y ++ L E++E F+G+ L+G +Y P FK
Sbjct: 242 -LDKDSNKKYILMESCLGILYKNPKKANFEILERFQGKALDGQKY-------EPLFPYFK 293
Query: 310 EKY-EWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGL-----PVYSPLDDQGK 363
+ E A ++ AD+V GTG+VH AP GE D++ G+ P+D+QG
Sbjct: 294 STFGERAFKLYSADYVEEGSGTGIVHQAPAFGEADYDAAWAAGIIDADHQPPCPVDEQGL 353
Query: 364 YTE--GKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFL 421
T + G YVK+AD +II L+ G+LVK +I H YP CWR TPLI+RA WF+
Sbjct: 354 LTSEITDFAGQYVKDADKEIIRSLKASGHLVKHSQIFHSYPFCWRSDTPLIYRAVPSWFV 413
Query: 422 KISKVKDKIIKENDEKVTWYPDWVK-IRFDNGVRDSGDWVISRQRYWGIPLPIWQSED-G 479
++ ++ ++++ EN W P ++ RF N ++++ DW ISR RYWG P+P+W S+D
Sbjct: 414 RVKEITNEMV-ENVMSTHWVPQNIRDKRFANWLKNARDWNISRNRYWGTPIPLWVSDDYE 472
Query: 480 EIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFII--K 537
E+ +GS +EL EL+ + D+HR +D I K
Sbjct: 473 EVVCIGSIKELEELSGVSNIT------------------------DIHRDSIDHITIPSK 508
Query: 538 VNGKDMRRVKDVVDVWFDSGIASWASLGYPRNK-ELFEKLWPADFIVEGEDQVTKWFYSQ 596
+ RV +V D WF+SG +AS YP + E F+ +PADFI EG DQ WFY+
Sbjct: 509 KGKGTLHRVSEVFDCWFESGSMPYASRHYPFERIEEFKHGFPADFISEGVDQTRGWFYTL 568
Query: 597 QAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWAT 656
+ FD PY+ V + G V+ E G KMSK L N P ++E+ G D R Y++
Sbjct: 569 TVLGTLLFDKAPYKNVIVSGLVMAEDGKKMSKRLKNYPEPNLIIEKYGSDALRLYLI--N 626
Query: 657 NP---WENLKFSWKGV-EQVRRMLNILWNVY----VLASTYMSLDNFDPRKLNPDELPFR 708
+P E LKF GV E V R+L WN Y A+ Y + D + L
Sbjct: 627 SPVVRAEILKFKEDGVREVVTRVLIPWWNSYKFFEAQAALYKKVTGKDFVFDDAATLSSN 686
Query: 709 EEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDP 768
D+WIL+R SLI V+ ++ + L L ++E+++ WY+R R+RL E +
Sbjct: 687 VMDRWILARCQSLIGFVDEEMKQYRLYTVVPQLLG-LIEEMTNWYIRFNRRRLKGEDGEI 745
Query: 769 DKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNL------IRPFTNVESVHMLDWPKVD 822
+ + A L++V L+R++ PFTP+I E IYQ+L + ++ SVH L +P
Sbjct: 746 ETINALNVLFEVLFTLVRIMGPFTPFITENIYQHLRNYMPIDKNEISLRSVHFLPFPTYK 805
Query: 823 EKAIDEELEREMEFIRRIVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRIL 882
+ DE + R ++ ++ I+E R++ I L+ P++ +I+ +E + + L R +
Sbjct: 806 SELDDETVLRRVKRMQTIIELARYVREQNNISLKTPLKTLIVILTNEEYLEDAKLLERYI 865
Query: 883 RDQLNAKEVKVGRVERE----LTIKPNFAKLGPEFKGDAKIIAKWI-NENGREL--YEKG 935
++LN +EV E + +++ ++ LG + + D + K + N E+ ++K
Sbjct: 866 AEELNVREVVFTSNEEKYGVVYSVQADWPVLGKKLRKDMARVKKALPNVTSEEVKEFQKN 925
Query: 936 ELTVEIDGKTFHLTREHIIVEEKLPDFFVSEEFEG-GRVFVDKTLTRELIAEGLAREFVR 994
+ V +DG II ++ + F+ +G V +D + +L AEGLARE +
Sbjct: 926 KKMV-LDGIELVEGDLQIIRSVEVKNEFLKSNTDGICIVLLDIEIDAQLQAEGLAREVIN 984
Query: 995 RIQEMRKRLDLDVNDRIIVTIETTDENVEL 1024
R+Q +RK+ +L V D + +T + ++ + L
Sbjct: 985 RVQRLRKKSNLQVTDDVRMTYKIKNDTIGL 1014
>gb|AAF51821.1| (AE003597) CG11471 gene product [alt 1] [Drosophila melanogaster]
>gi|7296538|gb|AAF51822.1| (AE003597) CG11471 gene
product [alt 2] [Drosophila melanogaster]
>gi|7296539|gb|AAF51823.1| (AE003597) CG11471 gene
product [alt 3] [Drosophila melanogaster]
Length = 1081
Score = 519 bits (1323), Expect = e-146
Identities = 328/1052 (31%), Positives = 536/1052 (50%), Gaps = 89/1052 (8%)
Query: 16 EEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRTM 75
EE V + W I+ K +L K PKY F DGPP+ +G H G IKD++ R+
Sbjct: 23 EENVLQKWRHENIFEKCSQLSKGKPKYTFYDGPPFATGLPHYGHILAGTIKDIVTRYAYQ 82
Query: 76 QGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIMTE 135
QGY+V R+ G+D HGLP+E ++++ L +K +++ K+G+ + +C++ +
Sbjct: 83 QGYHVDRRFGWDCHGLPVEFEIDKLLNIKGPEDVA-KMGIAAYNAECRKIVMRYADEWEN 141
Query: 136 QFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHE 195
+G W+D+ N Y T+ Y+ES W+ K+ ++KGL+ + +V+ + C T+L+ E
Sbjct: 142 VVTRVGRWIDFKNDYKTLYPWYMESIWWIFKQLFDKGLVYQGVKVMPYSTACTTSLSNFE 201
Query: 196 VRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVKVKVEFNG 255
YK DP + V N + L+WTTTPWTLP+N A HP YVKV+ +
Sbjct: 202 ANQNYKEVVDPCVVVALEAVSLPNTFFLVWTTTPWTLPSNFACCVHPTMTYVKVRDVKSD 261
Query: 256 REEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFKEKYEWA 315
R ++LA++ + V + + EV E+F G+ L+ L Y + R E K A
Sbjct: 262 R--LFVLAESRLSYVY-KSETEYEVKEKFVGKTLKDLHYKPLFPYFAKRGAEVK-----A 313
Query: 316 HRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGL-----PVYSPLDDQGKYTE--GK 368
+RV++ ++VT + GTG+VH AP GE+D+ V GL V P+D+ G++T
Sbjct: 314 YRVLVDEYVTEDSGTGIVHNAPYFGEDDYRVCLAAGLITKSSEVLCPVDEAGRFTNEASD 373
Query: 369 WKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKD 428
++G YVK++D +I+ L+ +G LV +G+++H YP CWR TPLI++A WF+++ +
Sbjct: 374 FEGQYVKDSDKQIMAALKARGNLVSSGQVKHSYPFCWRSDTPLIYKAVPSWFVRVEHMSK 433
Query: 429 KIIKENDEKVTWYPDWVK-IRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDG-EIYVVGS 486
++ + + W PD+VK RF N ++++ DW ISR RYWG P+PIW+S G E V+GS
Sbjct: 434 NLL-DCSSQTYWVPDFVKEKRFGNWLKEARDWAISRNRYWGTPIPIWRSPSGDETVVIGS 492
Query: 487 WRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIK---VNGKDM 543
++L EL+ ++V EDLHR +D I +
Sbjct: 493 IKQLAELS-GVQV------------------------EDLHRESIDHIEIPSAVPGNPPL 527
Query: 544 RRVKDVVDVWFDSGIASWASLGYP-RNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIV 602
RR+ V D WF+SG +A +P N++ F +PADFI EG DQ WFY+ S
Sbjct: 528 RRIAPVFDCWFESGSMPFAQQHFPFENEKDFMNNFPADFIAEGIDQTRGWFYTLLVISTA 587
Query: 603 AFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNP---W 659
F+ P++ + G VL G KMSK N P EVV + G D R Y++ +P
Sbjct: 588 LFNKAPFKNLIASGLVLAADGQKMSKRKKNYPDPMEVVHKYGADALRLYLI--NSPVVRA 645
Query: 660 ENLKFSWKGVEQVRRMLNILW-NVY-VLASTYMSLDNFD----PRKLNPDELPFREEDK- 712
E+L+F +GV + + + + W N Y L + + D + E + DK
Sbjct: 646 ESLRFKEEGVRDIIKDVFLPWYNAYRFLLQNIVRYEKEDLAGNGQYTYDRERHLKNMDKA 705
Query: 713 -----WILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGED 767
WILS SL+ ++ + L L F ++ L+ WYVRL R+R+ E
Sbjct: 706 SVIDVWILSFKESLLEFFATEMKMYRLYTVVPRLTKF-IDQLTNWYVRLNRRRIKGELGA 764
Query: 768 PDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLI-----RPFTNVESVHMLDWPKVD 822
+ + TL+ V +++++APFTPY+ E I+Q L+ + +SVH P
Sbjct: 765 DQCIQSLDTLYDVLYTMVKMMAPFTPYLTEYIFQRLVLFQPAGTLEHADSVHYQMMPVSQ 824
Query: 823 EKAIDEELEREMEFIRRIVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRIL 882
+K I ++ER + ++ +VE G R R + ++YPV II +D + +A++ L +
Sbjct: 825 KKFIRNDIERSVALMQSVVELGRVMRDRRTLPVKYPVSEIIAIHKDSQILEAIKTLQDFI 884
Query: 883 RDQLNAKEVKVGRVERE----LTIKPNFAKLGPEFKGDAKIIAKWINENGRELYEKGELT 938
+LN +++ + + + L +P+ LG KG+ K + I + E+
Sbjct: 885 LSELNVRKLTLSSDKEKYGVTLRAEPDHKALGQRLKGNFKAVMAAI-----KALRDDEIQ 939
Query: 939 VEIDGKTFHLTREHIIVEEKLPDFFVSEEFEGG---------RVFVDKTLTRELIAEGLA 989
++ F + + I ++E + SE+ G V +D T EL+ EGLA
Sbjct: 940 KQVSQGYFDILDQRIELDEVRIIYCTSEQVGGNFEAHSDNEVLVLLDMTPNEELLEEGLA 999
Query: 990 REFVRRIQEMRKRLDLDVNDRIIVTIETTDEN 1021
RE + R+Q+++K+ L D +++ E +N
Sbjct: 1000 REVINRVQKLKKKAQLIPTDPVLIFHELAADN 1031
>sp|P46215|SYI_SULAC ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|598398|gb|AAC41447.1| (L37106) transfer RNA-Ile
synthetase [Sulfolobus acidocaldarius]
Length = 552
Score = 516 bits (1314), Expect = e-145
Identities = 262/566 (46%), Positives = 368/566 (64%), Gaps = 43/566 (7%)
Query: 87 DMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIMTEQFKMLGIWMDW 146
D HGLPIEV+ E+ LG+K+K EI EK+GV+NFI KCKEFA+NN K +T+ F+ LGI+MDW
Sbjct: 1 DTHGLPIEVETEKRLGIKSKAEIIEKVGVDNFISKCKEFAVNNSKSLTQNFRNLGIFMDW 60
Query: 147 DNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHEVRGEYKLRKDP 206
+NPY T N+YI ++W +K + +GLL K VLHWC RCET LA++EV EY+ +DP
Sbjct: 61 ENPYFTFNNDYISNSWAVIK-SIRRGLLYKGVHVLHWCSRCETTLADYEV-SEYRDLEDP 118
Query: 207 SIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVKVKVEFNGREEYWILAKAL 266
SIYVKF V+G+ N YL+IWTTTPWTLPAN+ V + D++Y V+V +E ++AK
Sbjct: 119 SIYVKFRVKGEPNRYLVIWTTTPWTLPANVFVMINKDFEYADVRV----GDEILVIAKDR 174
Query: 267 VDKVLGEIGVKG-EVVEEFKGRELEGLRYVHILMDEYPRQKEFKEKYEWAHRVI-LADFV 324
V +++ E +K +++ +KG EL GL Y H L D Q + H+V+ + V
Sbjct: 175 VKELMKEARIKEYKILRVYKGEELLGLEYEHPLADIVSAQSKINNH----HKVLDGGEAV 230
Query: 325 TLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTE--GKWKGIYVKEADPKII 382
TL+EGTGLVH+APGHG+ DFE+G+KY +PV ++D+G++T+ GK+ G YV+ A +II
Sbjct: 231 TLQEGTGLVHSAPGHGDVDFEIGKKYDMPVVMLVNDKGEFTQDSGKYAGKYVRSASEEII 290
Query: 383 EHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKDKIIKENDEKVTWYP 442
L+++ L+ A +I H+YP CWRCKTPLI RA +QWF+ +SK+KD ++ E D +V W P
Sbjct: 291 SDLKQRSALLHASKIVHRYPVCWRCKTPLILRAIEQWFIAVSKLKDHLMGEID-RVRWIP 349
Query: 443 DWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQ-SEDGEIYVVGSWRELVELAVAIEVNG 501
DW K R N V++ DWVISRQR+WG PLPIW S I VVG EL ++ +
Sbjct: 350 DWGKTRIGNMVKEVRDWVISRQRFWGTPLPIWVCSNCQNIIVVGGVDELGKIPI------ 403
Query: 502 ERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKD--MRRVKDVVDVWFDSGIA 559
P+DLHRP++D+ ++ V + RR+ DV DVWFDSG+A
Sbjct: 404 ------------------NQVPQDLHRPWIDSVVLDVKNVEGQARRISDVADVWFDSGVA 445
Query: 560 SWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVAFDTVPYRRVAMHGYVL 619
+ASLG K + +L P D ++EG DQ+ WF+S ++ D PY V +HG++L
Sbjct: 446 FFASLGQDWRKR-WSELGPVDLVLEGHDQLRGWFFSLLRTGVILMDKAPYEAVLVHGFML 504
Query: 620 DEKGDKMSKSLGNIIRPEEVVERAGR 645
DE+G +M KS GN + P +VV + G+
Sbjct: 505 DEQGREMHKSSGNYVEPSQVVSKYGQ 530
>pir||T04047 isoleucine--tRNA ligase homolog F24G24.120 - Arabidopsis thaliana
>gi|4538961|emb|CAB39785.1| (AL049488) isoleucine-tRNA
ligase-like protein [Arabidopsis thaliana]
>gi|7267729|emb|CAB78155.1| (AL161517) isoleucine-tRNA
ligase-like protein [Arabidopsis thaliana]
Length = 1254
Score = 513 bits (1306), Expect = e-144
Identities = 351/1101 (31%), Positives = 552/1101 (49%), Gaps = 116/1101 (10%)
Query: 6 EFREYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKII 65
E +E+ + EE V FW+E + ++ + ++ P+Y F DGPP+ +G H G I
Sbjct: 6 EGKEFSFPRQEEDVLSFWTEIDAFKTQLKRTENLPEYIFYDGPPFATGLPHYGHILAGTI 65
Query: 66 KDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEF 125
KD++ R++TM G++V R+ G+D HGLP+E ++++ L +K + E+ K+G++ + ++C+
Sbjct: 66 KDIVTRYQTMTGHHVTRRFGWDCHGLPVENEIDRKLNIKRRDEV-IKMGIDKYNEECRSI 124
Query: 126 ALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCP 185
+ + G W+D+ N Y T+ ++ES W+ + WEK L+ + +V+ +
Sbjct: 125 VTRYVAEWEKVITRCGRWIDFKNDYKTMDLPFMESVWWVFSQLWEKNLVYRGFKVMPYST 184
Query: 186 RCETALAEHEVRGEYKLRKDPSIYVKFPVEG-KENEYLLIWTTTPWTLPANLAVSAHPDY 244
C+T L+ E YK DP I V FPV G ++N + WTTTPWTLP+NLA+ + +
Sbjct: 185 GCKTPLSNFEAGQNYKEVPDPEIMVTFPVIGDQDNAAFVAWTTTPWTLPSNLALCVNAKF 244
Query: 245 DYVKVKVEFNGREEYWILAKALV-----DKVLGEIG-------------VKG-------- 278
YVKV+ + G+ +I+A++ + DK ++ KG
Sbjct: 245 VYVKVRNKNTGK--VYIVAESRLSALPTDKPKAKLSNGPAGDTKKANPKAKGAKPESAAD 302
Query: 279 --EVVEEFKGRELEGLRYVHILMDEYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTA 336
EV+E+F G L G +Y P F + A RV+ D+VT + GTG+VH A
Sbjct: 303 SYEVLEKFNGASLVGKKY-------EPLFDYFSDFSSEAFRVVADDYVTDDSGTGIVHCA 355
Query: 337 PGHGEEDFEVGQ-----KYGLPVYSPLDDQGKYTE--GKWKGIYVKEADPKIIEHLREKG 389
P GE+D+ V K G + +DD G +TE + G YVK+AD IIE ++ KG
Sbjct: 356 PAFGEDDYRVCLLNKIIKKGENLVVAVDDDGLFTERITHFSGRYVKDADKDIIEAVKAKG 415
Query: 390 YLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKDKIIKENDEKVTWYPDWVK-IR 448
LVK G H YP CWR TPLI+RA WF+++ ++K+K++K N E+ W P +VK R
Sbjct: 416 RLVKTGSFTHSYPFCWRSDTPLIYRAVPSWFVRVEQLKEKLLKSN-EQTEWVPGYVKDKR 474
Query: 449 FDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVELAVAIEVNGERIELPE 508
F N + ++ DW ISR R+WG PLPIW S+DGE V+ E +E ++V
Sbjct: 475 FHNWLENARDWAISRSRFWGTPLPIWISDDGEEVVIMDSVEKLEKLSGVKV--------- 525
Query: 509 SYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKD----MRRVKDVVDVWFDSGIASWASL 564
DLHR ++D I + D +RRV+DV D WF+SG +A +
Sbjct: 526 ---------------FDLHRHHIDHITIPSSRGDEFGVLRRVEDVFDCWFESGSMPYAYI 570
Query: 565 GYP-RNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDEKG 623
YP NKELFEK +P DF+ EG DQ WFY+ S F+ ++ + +G VL E G
Sbjct: 571 HYPFENKELFEKNFPGDFVAEGLDQTRGWFYTLMVLSTALFEKPAFKNLICNGLVLAEDG 630
Query: 624 DKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNP---WENLKFSWKGVEQVRRMLNILW 680
KM+K L N P EV++ G D R Y++ +P E L+F +GV V + + + W
Sbjct: 631 KKMAKKLRNYPPPLEVIDEYGADAVRLYLI--NSPVVRAEPLRFKKEGVLGVVKDVFLPW 688
Query: 681 -NVY-VLASTYMSLDNFDPRKLNPDELPFREE----DKWILSRVNSLISEVENGIESFYL 734
N Y L L+ P +L + D+WI S SL+ V ++++ L
Sbjct: 689 YNAYRFLVQNAKRLETEGGVPFVPTDLATIQSANILDQWIHSATQSLVRFVREEMDAYRL 748
Query: 735 TKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFDVLLRLLAPFTPY 794
L F +++L+ YVR RKRL + D A TL+ V +++APFTP+
Sbjct: 749 YTVVPRLLKF-LDNLTNIYVRFNRKRLKGRTGEDDCHTALSTLFNVLLTSCKVMAPFTPF 807
Query: 795 IAEEIYQNLIRPFT-NVESVHMLDWPKVDEKAIDEELEREMEFIRRIVEAGSAARQRAKI 853
E +YQNL + + ESVH P E E +E + + +I++ R+R K+
Sbjct: 808 FTETLYQNLRKACKGSEESVHYCSIPP-REGMEGERIELSVTRMMKIIDLARNIRERNKL 866
Query: 854 KLRYPVRR-IIIETEDETVKKAVERLNRILRDQLNAKE-VKVGRVERELTIK--PNFAKL 909
L+ P++ I++ + + + L + ++LN + V + ++K P+F+ L
Sbjct: 867 PLKTPLKEMIVVHPDADFLNDITGVLREYVLEELNVRSLVPCNDTLKYASLKAEPDFSVL 926
Query: 910 GPEFKGDAKIIAKWINENGRE----LYEKGELTV------EIDGKTFHL------TREHI 953
G ++AK + E ++ E GE+T+ E D K H I
Sbjct: 927 GKRLGKSMGLVAKEVKEMSQKDILAFEEAGEVTIANHLLKETDIKVSHAMMFSCEIALRI 986
Query: 954 IVEEKLPDFFVSEEFEGG-----RVFVDKTLTRELIAEGLAREFVRRIQEMRKRLDLDVN 1008
+ K PD E + V +D L+ G ARE V RIQ++RK+ L+
Sbjct: 987 VRVFKRPDDLKENEIDSAGDGDVLVILDLRADDSLVEAGFAREIVNRIQKLRKKSGLEPT 1046
Query: 1009 DRIIVTIETTDENVELLKENL 1029
D + V ++ DE+ + K+ L
Sbjct: 1047 DFVEVYFQSLDEDESVSKQVL 1067
>sp|O66651|SYI_AQUAE ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|7437546|pir||G70327 isoleucine--tRNA ligase (EC
6.1.1.5) - Aquifex aeolicus >gi|2983002|gb|AAC06614.1|
(AE000683) isoleucyl-tRNA synthetase [Aquifex aeolicus]
Length = 956
Score = 507 bits (1291), Expect = e-142
Identities = 319/915 (34%), Positives = 508/915 (54%), Gaps = 79/915 (8%)
Query: 12 PKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIR 71
P++ + +EK+ +Y K+++ RK + DGPPY +G IH+G A NKI+KD+I +
Sbjct: 26 PQREPQILEKW---KGLYEKIQKERKGREVFVLHDGPPYANGHIHVGHALNKILKDVINK 82
Query: 72 FRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLK 131
+ + G NV PG+D HGLPIE VE+ L K K+ E + F + C+E+A +
Sbjct: 83 YNLLIGKNVNFIPGWDCHGLPIERAVEKELSKKKIKK--ESLPKTEFRELCREYAKKYVN 140
Query: 132 IMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETAL 191
I E F LG+ DW++PY+T+ +Y L + +E+GL + K+ ++WC +TA
Sbjct: 141 IQREDFVRLGVLGDWEHPYLTMDPKYEAQEIRELGKFFERGLAYRSKKPVYWCIYDKTAE 200
Query: 192 AEHEVRGEYKLRKDPSIYVKFPVEGKEN-------EYLLIWTTTPWTLPANLAVSAHPDY 244
AE EV EY ++DPSIYVKFP++ E + +IWTTTPWTLPANL + D
Sbjct: 201 AEAEV--EYYEKEDPSIYVKFPLKSGEKFGIKDKKVFAIIWTTTPWTLPANLGIMVKEDA 258
Query: 245 DYVKVKVEFNGREEYWILAKALVDKVLGEIG-VKGEVVEEFKGRELEGLRYVHILMDEYP 303
DYV V+VE +E WI+AK L+DK + +G V+E KG++L GL Y H +++
Sbjct: 259 DYVLVEVE----DEVWIVAKELMDKFFETVNRPEGLVLETVKGKDLVGLEYTHPFVEKEK 314
Query: 304 RQKEFKE---KYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDD 360
+ E K W ++ ++FV+L+ GTGLVH APGHG+ED+ VGQ+YGL Y+P+ D
Sbjct: 315 LKGHLSEETLKNMW--KIYPSEFVSLDTGTGLVHMAPGHGQEDYVVGQRYGLEPYAPVSD 372
Query: 361 QGKYTEGKWK---GIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATD 417
+G++ E + + V +A+ I+ L+EKG+LV +I H YPHCWRCK P+IFRAT
Sbjct: 373 EGRFVEPAPEFLINVRVFDANHLIVGVLKEKGFLVHEEKIRHSYPHCWRCKNPVIFRATP 432
Query: 418 QWFLKIS-----KVKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLP 472
QWF+ + K + E EKV W P++ K R + V + DW ISRQR+WG+P+
Sbjct: 433 QWFIGMDIEFFGKTLRQRALEEIEKVKWIPEYGKNRIKSMVENRPDWCISRQRFWGVPIT 492
Query: 473 IWQSED-GEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYV 531
++ E+ GEI RE+ E + N E+ + ++ +L PE P
Sbjct: 493 VFYCENCGEII---KDREVFERVAQLVENSEK-----GSDVWFELTSSQLLPEGYKCP-- 542
Query: 532 DAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTK 591
K G + +D++DVWFDSG S A++ P F+K AD +EG DQ
Sbjct: 543 -----KCGGDSFTKEEDILDVWFDSG-CSHAAVIRPLG---FQK---ADLYLEGSDQHRG 590
Query: 592 WFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFY 651
WF + S+ ++ PY+ V HG+++DEKG KMSKSLGN+I P+EVV+ G D R +
Sbjct: 591 WFQASLLESVGSYLEAPYKAVLTHGFIVDEKGRKMSKSLGNVISPQEVVKEFGADILRLW 650
Query: 652 MLWATNPWENLKFS----WKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPF 707
++ + + E++K K + R++ N L +++ + Y +F+PR + LPF
Sbjct: 651 VV-SEDYTEDVKLGKNLLKKIADDYRKIRNTL--RFIIGNLY----DFNPR---TNALPF 700
Query: 708 RE---EDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVE 764
+ D+WI+S + +L+ +V E F + + NFV+ LS Y+ +++ RL+V
Sbjct: 701 EKLHHFDRWIISELQNLLKKVHENYEKFLFYRVHNHIKNFVITTLSAIYLDVLKDRLYVY 760
Query: 765 GEDP-DKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNV-ESVHMLDWPKVD 822
++ +A LW + L AP+ + AEE+++++ + ++ ESV + + PK D
Sbjct: 761 APASWERRSAQTALWHLLIALTTSTAPYLSFTAEELWEHVGKLDPSLPESVFLYEMPKPD 820
Query: 823 EKAIDEELEREMEFIRR----IVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERL 878
E DEE+ ++ E + + ++ A AR+ I +++P + DE+V+ +++
Sbjct: 821 ENLKDEEVLKDYEILLKVRDEVMRALEVARKEKGI-IKHPYEAKVYIRGDESVESLLKKY 879
Query: 879 NRILRDQLNAKEVKV 893
L +V++
Sbjct: 880 EDYLNFFFTVSQVEL 894
>sp|P36422|SYI_TETTH ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|283498|pir||A42399 isoleucine--tRNA ligase (EC
6.1.1.5) - Tetrahymena thermophila
>gi|161801|gb|AAA30122.1| (M30942) transfer RNA-Ile
synthetase [Tetrahymena thermophila]
Length = 1081
Score = 506 bits (1288), Expect = e-142
Identities = 323/1051 (30%), Positives = 539/1051 (50%), Gaps = 85/1051 (8%)
Query: 11 DPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMII 70
D K EE + KFW E +++ E KD P + F DGPP+ +G H G IKD++
Sbjct: 15 DFPKEEENILKFWDEINAFKQQLEKTKDCPPFTFYDGPPFATGLPHYGNLLAGTIKDVVC 74
Query: 71 RFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNL 130
R+ + G V R+ G+D HGLP+E ++++ LG+ ++E+ K+GV+ + +C+ +
Sbjct: 75 RYASQNGKYVERRFGWDCHGLPVEYEIDKKLGITNRQEVL-KMGVDKYNAECRSIVMRYA 133
Query: 131 KIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETA 190
+ G W+D+DN Y T+ +++ES W+ K+ ++KGL+ + +V+ + C T
Sbjct: 134 QEWRSIVNRFGRWVDFDNDYKTLDLKFMESVWWVFKQMFDKGLVYRGCKVMPYSNGCATV 193
Query: 191 LAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVKVK 250
L+ E + YK DPS+++ F + WTTTPWTLP+NLA+ + D+DYVKV
Sbjct: 194 LSNFETQQNYKEVDDPSLFIAFKTAEDPKTKFIAWTTTPWTLPSNLALVINKDFDYVKVL 253
Query: 251 VEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFKE 310
+E++ILA+ + ++ + +++E+FKG EL G Y + R
Sbjct: 254 DA--KTQEHYILAECRLPELYKKDKDGYKILEKFKGSELVGREYEPLFPYFLSR------ 305
Query: 311 KYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGL------PVYSPLDDQGKY 364
K + R++ DFVT + GTG+VH APG G++D++V + PV P+D+ G +
Sbjct: 306 KQDGCFRILAGDFVTADAGTGIVHCAPGFGDDDYKVSVANNIIKPDDPPV--PVDENGHF 363
Query: 365 TE--GKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLK 422
T + G+Y+KEAD I ++L+E+G L+ +H YP CWR TPLI++A WF+K
Sbjct: 364 TNVVSDFAGVYIKEADKLIRKNLKERGLLLVDSSFKHNYPFCWRSDTPLIYKAVHCWFIK 423
Query: 423 ISKVKDKIIKENDEKVTWYPDWVKI-RFDNGVRDSGDWVISRQRYWGIPLPIWQSED-GE 480
++ +KD ++ N++K W P + + RF+N +++ DW SR R+WG P+PIW SED E
Sbjct: 424 VTALKDDLL-ANNKKAYWVPKFAQEGRFNNWLQNVSDWCFSRSRFWGNPIPIWVSEDFEE 482
Query: 481 IYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFII-KVN 539
+ +GS EL +L A E+ DLH+ ++D I
Sbjct: 483 VVCIGSVEELKKLTGATEIT------------------------DLHKDFIDHLTIPSQK 518
Query: 540 GKD-MRRVKDVVDVWFDSGIASWASLGYP--RNKELFEKLWPADFIVEGEDQVTKWFYSQ 596
GK +RR+ +V D WF+SG + YP N+E F K +PADFI EG DQ WFY+
Sbjct: 519 GKGVLRRIDEVFDCWFESGSMPYGQQHYPFSMNEEEFSKRFPADFIGEGIDQTRGWFYTL 578
Query: 597 QAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWAT 656
S ++ PY+ + ++G VL G KMSKS N P + + D R YM+
Sbjct: 579 NVISTALRNSNPYKNLIVNGIVLAADGKKMSKSKKNYDDPLLIASKYSVDAIRLYMI--N 636
Query: 657 NPW---ENLKFSWKGVEQVRRMLNILW-NVY---VLASTYMSL----DNFDPRKLNPDEL 705
+P E + F +GV V++ + + W N Y + + T L D +L+ D
Sbjct: 637 SPLVRAEEMSFKSEGVFAVKKDIFLPWYNAYKFLIQSITRWELATGKDYMFNEQLSVDTT 696
Query: 706 PF-REEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVE 764
D+WI+ +LI+ V +E ++L L +F +E+L+ WY+RL R RL +
Sbjct: 697 KLTNPTDRWIIISCQNLINYVRIEMEKYHLYNVVPRLIHF-LENLTNWYIRLNRNRLKGD 755
Query: 765 GEDPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTN-----VESVHMLDWP 819
++ + L+ V L++P P+I E YQNL + ES+H L P
Sbjct: 756 YGLEEQETSLNVLFNVILNSTILMSPLVPFITESFYQNLRKVIPKGSSYLEESIHFLRIP 815
Query: 820 KVDEKAIDEELEREMEFIRRIVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLN 879
++ +DE++ER E ++ I+ R++ K+ L+ P+ + + +D+ +++
Sbjct: 816 TPKQELLDEKIERNFERMQNIINFARTLREKRKVSLKQPIMSLTVINQDQEFHDSLKDYI 875
Query: 880 RILRDQLNAKEV--KVGRVER-ELTIKPNF----AKLGPEFKGDAKIIAKWINENGRELY 932
+ + D++N + ++ +L PN KLG E+ D K A N + +++
Sbjct: 876 QYIEDEINTPSILHEINTANYVDLKAIPNHKLLGQKLGKEYNKDLKAAAG--NLSAKDI- 932
Query: 933 EKGELTVEIDGKTFHLTREHIIVEEKLPDFFVSEEFE-GGR----VFVDKTLTRELIAEG 987
E + T ID L E + + + S + E GG + ++ +L ++G
Sbjct: 933 ETLKTTGSIDLVGKKLLLEDFTITQNYKKEYSSGDLELGGEGEVILLLNLAQDEKLKSKG 992
Query: 988 LAREFVRRIQEMRKRLDLDVNDRIIVTIETT 1018
L REF +Q+ +K+ L V+D I++ + T
Sbjct: 993 LVREFTSNVQKTKKKTGLKVDDNIVIYYDVT 1023
>sp|Q45477|SYI_BACSU ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|7437553|pir||H69643 isoleucine--tRNA ligase (EC
6.1.1.5) ileS - Bacillus subtilis
>gi|2633916|emb|CAB13417.1| (Z99112) isoleucyl-tRNA
synthetase [Bacillus subtilis]
Length = 921
Score = 499 bits (1272), Expect = e-140
Identities = 297/846 (35%), Positives = 464/846 (54%), Gaps = 65/846 (7%)
Query: 16 EEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRTM 75
E ++K W E +IYR V+E KD PK+ DGPPY +G IH+G A NKI+KD I+R+++M
Sbjct: 24 EPDIQKKWEEEDIYRLVQERTKDRPKFVLHDGPPYANGDIHMGHALNKILKDFIVRYKSM 83
Query: 76 QGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIMTE 135
GYN PG+D HGLPIE + K KK +++ V F K C+E+A ++ E
Sbjct: 84 SGYNAPYVPGWDTHGLPIETAL-----TKNKKVNRKEMSVAEFRKLCEEYAWKQIEGQRE 138
Query: 136 QFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHE 195
QFK LG+ DW+NPY+T+K EY ++G + K + ++W P E+ALAE E
Sbjct: 139 QFKRLGVRGDWENPYVTLKPEYEAQQIRVFGEMAKRGYIYKGLKPVNWSPSSESALAEAE 198
Query: 196 VRGEYKLRKDPSIYVKFPV-EGK----ENEYLLIWTTTPWTLPANLAVSAHPDYDYVKVK 250
+ EY+ ++ SIYV F V +GK E ++IWTTTPWT+PANL +S HPD +Y +
Sbjct: 199 I--EYQDKRSASIYVAFGVKDGKGVLENGERIIIWTTTPWTIPANLGISVHPDLEYSVIA 256
Query: 251 VEFNGREEYWILAKALVDKVLGEIGV-KGEVVEEFKGRELEGLRYVHILMDEYPRQKEFK 309
V E+ +++A ALV+ V G + EV KG++LE + H L
Sbjct: 257 V----GEDRFVVASALVENVASACGFDQYEVTRTVKGKDLENIIAEHPL----------- 301
Query: 310 EKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTEGK- 368
Y V+L + VT + GTG VHTAPGHGE+DF +GQKYGL V P+D++G T
Sbjct: 302 --YGRDSLVMLGEHVTTDAGTGCVHTAPGHGEDDFIIGQKYGLDVLCPVDEKGVMTSEAP 359
Query: 369 -WKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVK 427
++G++ +A+ I + L EKG LVK I H YPH WR K P IFRAT QWF I +
Sbjct: 360 GFEGMFYDDANKAITQQLDEKGALVKLEFITHSYPHDWRTKKPTIFRATAQWFASIKDFR 419
Query: 428 DKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSW 487
++ + ++ W P+W + R N VRD GDW ISRQR WG+P+P++ +E+GE +
Sbjct: 420 SDLL-DAIKETKWVPEWGEQRLHNMVRDRGDWCISRQRAWGVPIPVFYAENGEPVITDET 478
Query: 488 RELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVK 547
E ++ +G I + ++ L PE P NG + +
Sbjct: 479 IE--HVSELFRQHGSNIWFEKEAKDLL--------PEGFTHPG------SPNG-TFTKEQ 521
Query: 548 DVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVAFDTV 607
D++DVWFDSG + A L +E + + PAD +EG DQ WF S + ++
Sbjct: 522 DIMDVWFDSGSSHQAVL-----EERDDLVRPADLYLEGSDQYRGWFNSSLSTAVAVTGKA 576
Query: 608 PYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENLKFSWK 667
PY+ V HG+ LD +G KMSKS+GN++ P +V+++ G D R ++ + + +++ S
Sbjct: 577 PYKGVLSHGFALDGEGRKMSKSIGNVVVPAKVMKQLGADILRLWVS-SVDYQADVRVSDA 635
Query: 668 GVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISEVEN 727
++QV + + N + + +L +FDP+ RE D+++L ++N LI +V+
Sbjct: 636 ILKQVAEVYRKIRNTF--RFLHGNLFDFDPKTNAVAVEDLREVDQYMLIKLNKLIDKVKK 693
Query: 728 GIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGED-PDKLAAYYTLWKVFDVLLR 786
+ + +++NF +LS +Y+ + +++E D PD+ + ++ L++
Sbjct: 694 AYDEYEFAVVYHSIHNFCTIELSSFYLDFAKDIVYIEHADHPDRRSMQTVSYETLLALVK 753
Query: 787 LLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKV----DEKAIDEELEREMEFIRRIVE 842
L AP P+ A+E++ +L F +SV + D P+ + +A +E+ +R M +++
Sbjct: 754 LSAPILPHTADELWSHL--TFVEEQSVQLTDMPETITVPNSEATEEKFDRFMALRDDVLK 811
Query: 843 AGSAAR 848
A AR
Sbjct: 812 ALETAR 817
>sp|Q9ZCU4|SYI_RICPR ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|7437564|pir||B71667 isoleucine--tRNA ligase (EC
6.1.1.5) (ileS) RP617 - Rickettsia prowazekii
>gi|3861160|emb|CAA15060.1| (AJ235272) PROBABLE
ISOLEUCYL-TRNA SYNTHETASE (ileS) [Rickettsia prowazekii]
Length = 1086
Score = 483 bits (1230), Expect = e-135
Identities = 337/1117 (30%), Positives = 545/1117 (48%), Gaps = 128/1117 (11%)
Query: 15 LEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRT 74
+E+++ KFW N I++K + R ++ F DGPP+ +G H G IKD+ R++T
Sbjct: 19 IEQEILKFWQNNNIFQKSIDYRNGESEFIFYDGPPFANGLPHYGHLLTGFIKDVYARYKT 78
Query: 75 MQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIMT 134
++G V R+ G+D HGLP E++ E+ LG+ + I G+E F C+ +
Sbjct: 79 IKGKKVERRFGWDCHGLPAEMQSEKELGISGRIAI-TNFGIEKFNNHCRASVMQYASEWE 137
Query: 135 EQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEH 194
+ W+ + N Y T+ ++ES + K + K LL + RV+ + CET L+
Sbjct: 138 QYVTRQARWVAFKNAYKTMDKNFMESVLWAFKELYNKDLLYESMRVMPYSWACETPLSNF 197
Query: 195 EVR--GEYKLRKDPSIYVKFPV-----------------EGKE-NEY-LLIWTTTPWTLP 233
E R Y+ R D +I V F + EG EY +L WTTTPWTLP
Sbjct: 198 ETRLDNAYRERTDKAITVSFVLNEVTLINGIISQKSDMKEGDNFKEYRILAWTTTPWTLP 257
Query: 234 ANLAVSAHPDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKG-EVVEEFKGRELEGL 292
ANLA++ D DY V + E +I+A + V K E+G+ G E E KG +L+GL
Sbjct: 258 ANLALAVGSDIDYAFV----DKNEVCYIIAASSVAKYAKELGLSGKENFEIIKGLKLQGL 313
Query: 293 RYVHILMDEYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGL 352
Y + + E + + ++ +DFV +GTG+VH APG GE+D + + G+
Sbjct: 314 SYKPLF--------NYFENHPNSFKIFASDFVVEGDGTGIVHMAPGFGEDDQILCESKGI 365
Query: 353 PVYSPLDDQGKYTE--GKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTP 410
+ P+D+ GK+T+ +G+ V +A+ KII L+E+G +K + H YPHCWR TP
Sbjct: 366 ELVCPVDNSGKFTKEIPDLEGVQVFDANDKIIIKLKEQGNWIKTEQYIHNYPHCWRTDTP 425
Query: 411 LIFRATDQWFLKISKVKDKIIKENDEKVTWYPDWVKIR-FDNGVRDSGDWVISRQRYWGI 469
LI++A W+++++K KD++++ N +++ W P VK F + ++ DW ISR R+WG
Sbjct: 426 LIYKAVPSWYVRVTKFKDRMVELN-QQINWIPHNVKDNLFGKWLENARDWSISRNRFWGT 484
Query: 470 PLPIWQSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRP 529
PLP+W+S+D + I+V G E+ + + K+ DLHRP
Sbjct: 485 PLPVWKSDDPKY-------------PRIDVYGSIEEIEKDFGVKI---------NDLHRP 522
Query: 530 YVDAFIIKVNGKD------MRRVKDVVDVWFDSGIASWASLGYP-RNKELFEKLWPADFI 582
++D + + N D MRR+ DV D WF+SG + + YP NK+ F + +PADFI
Sbjct: 523 FIDE-LTRTNPDDPTGKSTMRRIDDVFDCWFESGSMPYGQVHYPFENKKWFVEHFPADFI 581
Query: 583 VEGEDQVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVER 642
VE Q WFY+ S FD P+ HG +LD G K+SK L N P E+ ++
Sbjct: 582 VEYSSQTRGWFYTLMVLSTALFDRPPFLNCICHGVILDATGQKLSKRLNNYADPLELFDK 641
Query: 643 AGRDTFRFYMLWA-TNPWENLKFSWKG---VEQVRRMLNILWNVYVLASTYMSLDNFDPR 698
G D R ML + + L G + +R + +WN Y + Y + D+
Sbjct: 642 YGSDALRVTMLSSNVVKGQELLIDKDGKMVFDTLRLFIKPIWNAYHFFTIYANADSL--- 698
Query: 699 KLNPDELPFREE---DKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVR 755
L F + D +ILS++ ++++E +++F A A+ F E L+ WY+R
Sbjct: 699 ---KGTLNFASQNVLDVYILSKLKIAVNKIEESLDNFDTQTAYHAVSEF-FEVLNNWYIR 754
Query: 756 LIRKRLWVEGEDPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNL------------ 803
R R W +D DK AY TL+ ++ ++ P I+E IYQ L
Sbjct: 755 RSRARFWKNEKDTDKQNAYNTLYSCLKIMTIAMSALIPMISETIYQGLHNTAITQLNCLL 814
Query: 804 -------IRPFTNVE----SVHMLDWPKVDEKAIDEELEREMEFIRRIVEAGSAARQRAK 852
P ++ + SVH+ ++P + + I+ EL M+ + I R
Sbjct: 815 SEGKHIVQNPMSDTQDYNTSVHLCNYPTLSDFEINYELVSTMDNVLDICSNSLFIRSTEN 874
Query: 853 IKLRYPVRRIIIETEDETVKKAVERLNRILRDQLNAKEVKVGRVERE----LTIKPNFAK 908
I++R P+ I I ++ K E L ++D++N K V + R + E + NFA
Sbjct: 875 IRVRQPLACITIISKHNNNLKDFEDL---IKDEINVKTV-IYRDDLENYARKKLSLNFAI 930
Query: 909 LGPEFKGDAKIIAKWINENGRELYEKGELTVEIDGKTFHLTREHIIVEEKLPDFFVSEEF 968
LG K I I+ + +E L + I G+ + + E+ ++ E + F
Sbjct: 931 LGKRLPHKMKAI---IDAAKKGEWEATTLGLAICGEILN-SDEYTLILEPYSHIKGTANF 986
Query: 969 EGGR--VFVDKTLTRELIAEGLAREFVRRIQEMRKRLDLDVNDRIIVTIETTDENVELLK 1026
+ + ++ LT ELI EG AR+ VR IQ RK D + DRI++ I + + +++
Sbjct: 987 DNNSSLLILNLELTSELIEEGYARDIVRFIQYARKEADFSITDRILIEIISEFDLSKIID 1046
Query: 1027 ENLDYIMRETRADKIVFGKAKGYVVEWPEVQAKIGIE 1063
D+I +T + AK + P+ +K+ +E
Sbjct: 1047 HYGDFIKEQTLGE-----FAKNFT---PDYVSKVALE 1075
>sp|P41972|SYI_STAAU ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|541337|pir||S40178 isoleucine--tRNA ligase (EC
6.1.1.5) - Staphylococcus aureus
>gi|437916|emb|CAA52296.1| (X74219) isoleucyl-tRNA
synthetase [Staphylococcus aureus]
Length = 917
Score = 479 bits (1219), Expect = e-134
Identities = 307/890 (34%), Positives = 477/890 (53%), Gaps = 87/890 (9%)
Query: 16 EEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRTM 75
E ++++ W + Y K E K + DGPPY +G +H+G A NKI+KD I+R++TM
Sbjct: 24 EPQIQEKWDAEDQYHKALEKNKGNETFILHDGPPYANGNLHMGHALNKILKDFIVRYKTM 83
Query: 76 QGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIE-EKIGVENFIKKCKEFALNNLKIMT 134
QG+ PG+D HGLPI EQAL TKK ++ +K+ F +KCKEFAL +++
Sbjct: 84 QGFYAPYVPGWDTHGLPI----EQAL---TKKGVDRKKMSTAEFREKCKEFALEQIELQK 136
Query: 135 EQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEH 194
+ F+ LG+ D+++PY+T+K EY + +KGL+ K K+ ++W P E++LAE
Sbjct: 137 KDFRRLGVRGDFNDPYITLKPEYEAAQIRIFGEMADKGLIYKGKKPVYWSPSSESSLAEA 196
Query: 195 EVRGEYKLRKDPSIYVKFPVEGKE-----NEYLLIWTTTPWTLPANLAVSAHPDYDYVKV 249
E+ EY ++ SIYV F V+ + + +IWTTTPWT+P+N+A++ HP+ Y
Sbjct: 197 EI--EYHDKRSASIYVAFNVKDDKGVVDADAKFIIWTTTPWTIPSNVAITVHPELKY--- 251
Query: 250 KVEFNGREEYWILAKALVDKVLGEIG---VKGEVVEEFKGRELEGLRYVHILMDEYPRQK 306
++N E +I+A+AL D V + ++ +E+ G+ELE + H +D
Sbjct: 252 -GQYNVNGEKYIIAEALSDAVAEALDWDKASIKLEKEYTGKELEYVVAQHPFLDR----- 305
Query: 307 EFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTE 366
VI D VT + GTG VHTAPGHGE+D+ VGQKY LPV SP+DD+G +TE
Sbjct: 306 --------ESLVINGDHVTTDAGTGCVHTAPGHGEDDYIVGQKYELPVISPIDDKGVFTE 357
Query: 367 --GKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKIS 424
G+++G++ +A+ + + L EKG L+K I H YPH WR K P+IFRAT QWF IS
Sbjct: 358 EGGQFEGMFYDKANKAVTDLLTEKGALLKLDFITHSYPHDWRTKKPVIFRATPQWFASIS 417
Query: 425 KVKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVV 484
KV+ I+ + E + +W K R N VRD G+WVISRQR WG+PLP++ +E+GEI +
Sbjct: 418 KVRQDIL-DAIENTNFKVNWGKTRIYNMVRDRGEWVISRQRVWGVPLPVFYAENGEIIMT 476
Query: 485 GSWRELV-ELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDM 543
+E V +A +G I ++ L PE P NG
Sbjct: 477 ---KETVNHVADLFAEHGSNIWFEREAKDLL--------PEGFTHPG------SPNG-TF 518
Query: 544 RRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVA 603
+ D++DVWFDSG + L + E +PAD +EG DQ WF S S+
Sbjct: 519 TKETDIMDVWFDSGSSHRGVL-----ETRPELSFPADMYLEGSDQYRGWFNSSITTSVAT 573
Query: 604 FDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENLK 663
PY+ + HG+V+D +G KMSKSLGN+I P++VV++ G D R ++ +T+ +++
Sbjct: 574 RGVSPYKFLLSHGFVMDGEGKKMSKSLGNVIVPDQVVKQKGADIARLWVS-STDYLADVR 632
Query: 664 FSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLIS 723
S + ++Q + + N L ++++F+P + E E D+++L+R+ +
Sbjct: 633 ISDEILKQTSDVYRKIRN--TLRFMLGNINDFNPDTDSIPESELLEVDRYLLNRLREFTA 690
Query: 724 EVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYT-LWKVFD 782
N E+F + + NF+ +LS +Y+ + L++E D + T L+++
Sbjct: 691 STINNYENFDYLNIYQEVQNFINVELSNFYLDYGKDILYIEQRDSHIRRSMQTVLYQILV 750
Query: 783 VLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREMEFIRRIVE 842
+ +LLAP + AEE++ + P ESVH+ D PKV E V+
Sbjct: 751 DMTKLLAPILVHTAEEVWSH--TPHVKEESVHLADMPKVVE-----------------VD 791
Query: 843 AGSAARQRAKIKLRYPVRRIIIETEDETV--KKAVERLNRILRDQLNAKE 890
+ R + LR V R + +E V K ++ D+ NA E
Sbjct: 792 QALLDKWRTFMNLRDDVNRALETARNEKVIGKSLEAKVTIASNDKFNASE 841
>dbj|BAB06264.1| (AP001515) isoleucyl-tRNA synthetase [Bacillus halodurans]
Length = 921
Score = 476 bits (1213), Expect = e-133
Identities = 296/832 (35%), Positives = 459/832 (54%), Gaps = 68/832 (8%)
Query: 16 EEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRTM 75
E ++++ W + IY KV+ K P + DGPPY +G IH+G A NK++KDMI+R+++M
Sbjct: 24 EPQMQEEWKDMNIYEKVQARTKGRPLFVLHDGPPYANGDIHMGHALNKVLKDMIVRYKSM 83
Query: 76 QGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEK-IGVENFIKKCKEFALNNLKIMT 134
G++ PG+D HGLPI EQAL TK ++ K + V F K C+EFA +
Sbjct: 84 AGFHAPYVPGWDTHGLPI----EQAL---TKSGVDRKSMSVAEFRKLCEEFARKQIDRQR 136
Query: 135 EQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEH 194
EQF LG+ DW NPY+T+ + +KG + K K+ ++W P E+ALAE
Sbjct: 137 EQFMRLGVRGDWWNPYVTLDKGFEAQQVKVFGEMAKKGYIYKGKKPVYWSPSSESALAEA 196
Query: 195 EVRGEYKLRKDPSIYVKFPV-EGK----ENEYLLIWTTTPWTLPANLAVSAHPDYDYVKV 249
E+ EY ++ PSIYV FPV +GK ++E ++IWTTTPWT+PANL ++ HP+ +Y V
Sbjct: 197 EI--EYHDKRSPSIYVAFPVKDGKNVLQQDEKIVIWTTTPWTIPANLGIAVHPELEYSVV 254
Query: 250 KVEFNGREEYWILAKALVDKVLGEIGVKG-EVVEEFKGRELEGLRYVHILMDEYPRQKEF 308
V + E +++A LV+ + + + E++ KG +LE ++ E+P
Sbjct: 255 AV----KGEKYVVASGLVETLESALEWENPEILRTIKGVDLE------YVVAEHP----- 299
Query: 309 KEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTEGK 368
Y V+L D VTL+ GTG VHTAPGHGEED+ VGQKYGL V P+DD+G T
Sbjct: 300 --IYGRDSLVVLGDHVTLDAGTGCVHTAPGHGEEDYIVGQKYGLDVLCPVDDKGYMTAEA 357
Query: 369 --WKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKV 426
++G++ EA+ I + L E G L+K I H Y H WR K P+I+RAT QWF I
Sbjct: 358 PGFEGLFYDEANKPITQKLDECGALLKLTFITHSYAHDWRTKKPVIYRATAQWFASIENF 417
Query: 427 KDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGS 486
+D++++ E V W P+W + R N VRD GDW ISRQR WG+P+PI+ E+GE +
Sbjct: 418 RDELLRAIQE-VKWVPEWGETRLYNMVRDRGDWCISRQRVWGVPIPIFYGENGEPIITD- 475
Query: 487 WRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRV 546
+ ++ +G + +E K L PE NG+ R +
Sbjct: 476 -ETINHVSELFRKHGSNVWF--EWETK------DLLPEGFTHE------SSPNGQFTREM 520
Query: 547 KDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVAFDT 606
D++DVWFDSG + L E E PAD +EG DQ WF S + S+
Sbjct: 521 -DIMDVWFDSGSSHQGVL-----VEREELDRPADLYLEGSDQYRGWFNSSLSTSVAITGK 574
Query: 607 VPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENLKFSW 666
PY+ V HG+ LD +G KMSKSLGN++ P +V+++ G D R ++ + + +++ S
Sbjct: 575 APYKGVLSHGFTLDGEGKKMSKSLGNVVIPNDVMKQLGADILRLWVA-SVDYQADVRVSD 633
Query: 667 KGVEQVRRMLNILWNVYVLASTYMSLDNFDP--RKLNPDELPFREEDKWILSRVNSLISE 724
K ++QV + + N Y +L +F P ++ D+L D+++L+++N +I+
Sbjct: 634 KILKQVSEVYRKIRNTY--RFLLGNLHDFHPATHRVAIDQL--NGLDRYMLAKLNDVINR 689
Query: 725 VENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGED-PDKLAAYYTLWKVFDV 783
V+ + + + L+NF +LS +Y+ + + L+V+ D PD+ A ++ V
Sbjct: 690 VKKAYDEYQFSTVYHELHNFCTIELSSFYMDIAKDTLYVKHADHPDRRATQTVMYDVLVA 749
Query: 784 LLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREME 835
L +LL+P P+ A+E+++++ P ESV + D P+ E EL+++ +
Sbjct: 750 LAKLLSPIIPHTADEVWKHI--PGVEEESVQLTDMPEPIELGDVSELKQKWD 799
>pdb|1FFY|A Chain A, Insights Into Editing From An Ile-Trna Synthetase
Structure With Trna(Ile) And Mupirocin
>gi|6137708|pdb|1QU2|A Chain A, Insights Into Editing
From An Ile-Trna Synthetase Structure With Trna(Ile) And
Mupirocin >gi|6137710|pdb|1QU3|A Chain A, Insights Into
Editing From An Ile-Trna Synthetase Structure With
Trna(Ile) And Mupirocin
Length = 917
Score = 476 bits (1212), Expect = e-133
Identities = 306/890 (34%), Positives = 476/890 (53%), Gaps = 87/890 (9%)
Query: 16 EEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRTM 75
E ++++ W + Y K E K + DGPPY +G +H+G A NKI+KD I+R++TM
Sbjct: 24 EPQIQEKWDAEDQYHKALEKNKGNETFILHDGPPYANGNLHMGHALNKILKDFIVRYKTM 83
Query: 76 QGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIE-EKIGVENFIKKCKEFALNNLKIMT 134
QG+ PG+D HGLPI EQAL TKK ++ +K+ F +KCKEFAL +++
Sbjct: 84 QGFYAPYVPGWDTHGLPI----EQAL---TKKGVDRKKMSTAEFREKCKEFALEQIELQK 136
Query: 135 EQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEH 194
+ F+ LG+ D+++PY+T+K EY + +KGL+ K K+ ++W P E++LAE
Sbjct: 137 KDFRRLGVRGDFNDPYITLKPEYEAAQIRIFGEMADKGLIYKGKKPVYWSPSSESSLAEA 196
Query: 195 EVRGEYKLRKDPSIYVKFPVEGKE-----NEYLLIWTTTPWTLPANLAVSAHPDYDYVKV 249
E+ EY ++ SIYV F V+ + + +IWTTTPWT+P+N+A++ HP+ Y
Sbjct: 197 EI--EYHDKRSASIYVAFNVKDDKGVVDADAKFIIWTTTPWTIPSNVAITVHPELKY--- 251
Query: 250 KVEFNGREEYWILAKALVDKVLGEIG---VKGEVVEEFKGRELEGLRYVHILMDEYPRQK 306
++N E +I+A+AL D V + ++ +E+ G+ELE + H +D
Sbjct: 252 -GQYNVNGEKYIIAEALSDAVAEALDWDKASIKLEKEYTGKELEWVVAQHPFLDR----- 305
Query: 307 EFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTE 366
VI D VT + GTG VHTAPGHGE+D+ VGQ+Y LPV SP+DD+G +TE
Sbjct: 306 --------ESLVINGDHVTTDAGTGCVHTAPGHGEDDYIVGQQYELPVISPIDDKGVFTE 357
Query: 367 --GKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKIS 424
G+++G++ +A+ + + L EKG L+K I H YPH WR K P+IFRAT QWF IS
Sbjct: 358 EGGQFEGMFYDKANKAVTDLLTEKGALLKLDFITHSYPHDWRTKKPVIFRATPQWFASIS 417
Query: 425 KVKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVV 484
KV+ I+ + E + +W K R N VRD G+WVISRQR WG+PLP++ +E+GEI +
Sbjct: 418 KVRQDIL-DAIENTNFKVNWGKTRIYNMVRDRGEWVISRQRVWGVPLPVFYAENGEIIMT 476
Query: 485 GSWRELV-ELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDM 543
+E V +A +G I ++ L PE P NG
Sbjct: 477 ---KETVNHVADLFAEHGSNIWFEREAKDLL--------PEGFTHPG------SPNG-TF 518
Query: 544 RRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVA 603
+ D++DVWFDSG + L + E +PAD +EG DQ WF S S+
Sbjct: 519 TKETDIMDVWFDSGSSHRGVL-----ETRPELSFPADMYLEGSDQYRGWFNSSITTSVAT 573
Query: 604 FDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENLK 663
PY+ + HG+V+D +G KMSKSLGN+I P++VV++ G D R ++ +T+ +++
Sbjct: 574 RGVSPYKFLLSHGFVMDGEGKKMSKSLGNVIVPDQVVKQKGADIARLWVS-STDYLADVR 632
Query: 664 FSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLIS 723
S + ++Q + N L ++++F+P + E E D+++L+R+ +
Sbjct: 633 ISDEILKQTSDDYRKIRN--TLRFMLGNINDFNPDTDSIPESELLEVDRYLLNRLREFTA 690
Query: 724 EVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYT-LWKVFD 782
N E+F + + NF+ +LS +Y+ + L++E D + T L+++
Sbjct: 691 STINNYENFDYLNIYQEVQNFINVELSNFYLDYGKDILYIEQRDSHIRRSMQTVLYQILV 750
Query: 783 VLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREMEFIRRIVE 842
+ +LLAP + AEE++ + P ESVH+ D PKV E V+
Sbjct: 751 DMTKLLAPILVHTAEEVWSH--TPHVKEESVHLADMPKVVE-----------------VD 791
Query: 843 AGSAARQRAKIKLRYPVRRIIIETEDETV--KKAVERLNRILRDQLNAKE 890
+ R + LR V R + +E V K ++ D+ NA E
Sbjct: 792 QALLDKWRTFMNLRDDVNRALETARNEKVIGKSLEAKVTIASNDKFNASE 841
>sp|P73505|SYI_SYNY3 ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|7437554|pir||S77211 isoleucine--tRNA ligase (EC
6.1.1.5) - Synechocystis sp. (strain PCC 6803)
>gi|1652625|dbj|BAA17545.1| (D90907) isoleucyl-tRNA
synthetase [Synechocystis sp.]
Length = 988
Score = 453 bits (1153), Expect = e-126
Identities = 299/875 (34%), Positives = 461/875 (52%), Gaps = 92/875 (10%)
Query: 14 KLEEKVEKFWSENEIYRKVKELRKDGPKYYFL--DGPPYVSGAIHLGTAWNKIIKDMIIR 71
K E +++++W E IY +L + PK F+ DGPPY +GA+H+G A NK++KD+I +
Sbjct: 26 KREPEIQQYWQEKGIYA---DLADNNPKDLFVLHDGPPYANGALHMGHALNKVLKDIINK 82
Query: 72 FRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLK 131
++ +QG+ V PG+D HGLPIE+KV Q+L + E+ K ++FAL +
Sbjct: 83 YKLLQGHKVHYVPGWDCHGLPIELKVLQSLKSSERAELTPL----TLRHKARDFALKAQQ 138
Query: 132 IMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETAL 191
F+ GIW DW PY+T+ EY + KG + + + +HW P TAL
Sbjct: 139 EQAVGFQRYGIWGDWKKPYLTLTPEYEAAQIGVFGAMALKGYIYRGLKPVHWSPSSRTAL 198
Query: 192 AEHEVRGEY-KLRKDPSIYVKFPVE--GKENEYLL----------IWTTTPWTLPANLAV 238
AE E+ EY + SIYV FP+ G++ +L IWTTTPWTLP NLAV
Sbjct: 199 AEAEL--EYPEGHTSRSIYVSFPITQAGEKAAEILAPYIDDLAVAIWTTTPWTLPGNLAV 256
Query: 239 SAHPDYDYVKVKVEFN-GREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHI 297
+ +P+ Y V+ E + Y I+A LV+K+ GVK V +G LE Y H
Sbjct: 257 ALNPELTYAVVETESHIFHRSYLIVALDLVEKLSETFGVKLTVKVTLQGESLENTCYQHP 316
Query: 298 LMDEYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSP 357
L D + VI D+VT E GTGLVHTAPGHG+ED+ VGQ+YGLP+ SP
Sbjct: 317 LFDRV------------SPIVIGGDYVTTESGTGLVHTAPGHGQEDYVVGQRYGLPILSP 364
Query: 358 LDDQGKYTE--GKWKGIYV-KEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFR 414
+D G TE GK+ G+ V +A+ II L+++ L+K EHKYP+ WR K P IFR
Sbjct: 365 VDAAGNLTEEAGKFAGLNVLNDANEAIINALQDQKVLLKEEAYEHKYPYDWRTKKPTIFR 424
Query: 415 ATDQWFLKISKVKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIW 474
AT+QWF + +D+ +K E VTW P + R V D DW ISRQR WG+P+P++
Sbjct: 425 ATEQWFASVEGFRDQALKAIKE-VTWIPTQGENRITPMVGDRSDWCISRQRAWGVPIPVF 483
Query: 475 QSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAF 534
E+ E + E+ ++I EK G + V+
Sbjct: 484 YDEE---------------------TSEPLLTEETINHVQQIIAEK-GSDAWWELTVEEL 521
Query: 535 IIKV---NGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTK 591
+ + NG+ R+ +D +DVWFDSG +SWA++ +N+ L +P D +EG DQ
Sbjct: 522 LPEAYRNNGRTYRKGEDTMDVWFDSG-SSWAAVANAKNRPL---KYPVDMYLEGSDQHRG 577
Query: 592 WFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERA-------- 643
WF S S+ PY+ V HG+VLDEKG KMSKSLGN++ P +++
Sbjct: 578 WFQSSLLTSVAVNGIAPYKTVLTHGFVLDEKGHKMSKSLGNVVDPYQIINGGKNQKQEPA 637
Query: 644 -GRDTFRFYMLWATNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYM-SLDNFDPR--K 699
G D R ++ A+ + N +G+ ++++++I + A + +L +F+P
Sbjct: 638 YGADVLRLWV--ASVDYANDVPIGQGI--LKQLVDIRNKIRNTARFLLGNLHDFNPETDA 693
Query: 700 LNPDELPFREEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRK 759
+ ++LP E D+++L R+ + +EV ESF K + + NF V DLS +Y+ + +
Sbjct: 694 VAYEDLP--ELDRYMLHRMTEVFTEVTEAYESFQFFKFFQTVQNFCVVDLSNFYLDIAKD 751
Query: 760 RLWVEGED-PDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTN-VESVHMLD 817
RL++ + P + + L + L + +AP ++AE+I+Q L P+ ESV
Sbjct: 752 RLYISAPNAPRRRSCQTILQLALENLTKAIAPVLCHLAEDIWQFL--PYEKPTESVFQSG 809
Query: 818 WPKVDEKAIDEELEREMEFIRRIVEAGSAARQRAK 852
W +D + +L ++ +R++ + + ++A+
Sbjct: 810 WVNLDAQWQQPQLAQKWVSLRQLRDGINQLLEQAR 844
>sp|P43824|SYI_HAEIN ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|7437547|pir||S78633 isoleucine--tRNA ligase (EC
6.1.1.5) - Haemophilus influenzae (strain Rd KW20)
Length = 941
Score = 440 bits (1119), Expect = e-122
Identities = 311/984 (31%), Positives = 500/984 (50%), Gaps = 133/984 (13%)
Query: 11 DPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMII 70
D K E K W E +Y+K+++ K + DGPPY +G IH+G A NKI+KD+II
Sbjct: 21 DLAKREPDKXKNWYEKNLYQKIRKASKGKKSFILHDGPPYANGNIHIGHAVNKILKDIII 80
Query: 71 RFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNL 130
+ +T G++ PG+D HGLPIE+KVE +G + EKI F +KC+E+A +
Sbjct: 81 KSKTALGFDSPYIPGWDCHGLPIELKVEGLVG-----KPNEKISAAEFRQKCREYAAEQV 135
Query: 131 KIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETA 190
+ + F LG+ DWDNPY+T+ + + TL + E G L K + +HWC C ++
Sbjct: 136 EGQKKDFIRLGVLGDWDNPYLTMNFDTEANIIRTLGKVIENGHLYKGSKPVHWCLDCGSS 195
Query: 191 LAEHEVRGEYKLRKDPSIYVKFPVE--------------GKENEYLLIWTTTPWTLPANL 236
LAE EV EY+ + PSIYV+FP E G+ +IWTTTPWT+P+N
Sbjct: 196 LAEAEV--EYEDKVSPSIYVRFPAESADEIEAKFSAQGRGQGKLSAIIWTTTPWTMPSNR 253
Query: 237 AVSAHPDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKG-EVVEEFKGRELEGLRYV 295
A++ + D +Y V++ +E ILA LV+ V +G++ E++ KG +LE R+
Sbjct: 254 AIAVNADLEYNLVQL----GDERVILAAELVESVAKAVGIEHIEILGSVKGDDLELSRFH 309
Query: 296 HILMDEYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVY 355
H Y++ VIL D VT + GTGLVHTAP HG +DF VG++Y LP+
Sbjct: 310 HPF-------------YDFTVPVILGDHVTTDGGTGLVHTAPDHGLDDFIVGKQYDLPMA 356
Query: 356 SPLDDQGKY--TEGKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIF 413
+ + GK+ T + G V EA+P +IE L+E G L+K +I+H YPHCWR KTP+IF
Sbjct: 357 GLVSNDGKFISTTEFFAGKGVFEANPLVIEKLQEVGNLLKVEKIKHSYPHCWRHKTPIIF 416
Query: 414 RATDQWF--LKISKVKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPL 471
RAT QWF ++ ++ + + E ++V W PDW + R + V + DW ISRQR WG+P+
Sbjct: 417 RATPQWFIGMETQGLRQQALGE-IKQVRWIPDWGQARIEKMVENRPDWCISRQRTWGVPM 475
Query: 472 PIWQSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYV 531
++ ++ E + L E+A +E G I+ +EK E LG
Sbjct: 476 TLFVHKETEELHPRTLDLLEEVAKRVERAG--IQAWWDLDEK-----ELLG--------- 519
Query: 532 DAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTK 591
+ + R+V D +DVWFDSG ++++S+ R + + + D +EG DQ
Sbjct: 520 ------ADAETYRKVPDTLDVWFDSG-STYSSVVANRLEFNGQDI---DMYLEGSDQHRG 569
Query: 592 WFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFY 651
WF S S PY++V HG+ +D +G KMSKS+GNI+ P+EV+++ G D R +
Sbjct: 570 WFMSSLMLSTATDSKAPYKQVLTHGFTVDGQGRKMSKSIGNIVTPQEVMDKFGGDILRLW 629
Query: 652 MLWATNPWE---NLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRK--LNPDELP 706
+ E + + + + RR+ N ++LA +L+ FDP++ + P+++
Sbjct: 630 VASTDYTGEMTVSDEILKRAADSYRRIRNTA--RFLLA----NLNGFDPKRDLVKPEKM- 682
Query: 707 FREEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGE 766
D+W ++ +E+++ +++ + L F ++ +Y+ +I+ R +
Sbjct: 683 -ISLDRWAVACALDAQNEIKDAYDNYQFHTVVQRLMRFCSVEMGSFYLDIIKDRQYTTKA 741
Query: 767 DP-DKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKA 825
D + + LW + + L+R +AP + A+EI+Q+L P T
Sbjct: 742 DSLARRSCQTALWHIAEALVRWMAPILSFTADEIWQHL--PQT----------------- 782
Query: 826 IDEELEREMEFIRRIVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQ 885
E E F + + K+ Y + I + +E +NR+L
Sbjct: 783 --ESARAEFVFTEEFYQGLFGLGEDEKLDDAYWQQLIKVRSE----------VNRVLEIS 830
Query: 886 LNAKEVKVGRVERELTIKPN------FAKLGPEFKG---DAKIIAKWINENGRELYEKGE 936
N KE+ G +E E+T+ N A+LG E + +K+ K ++E +L +
Sbjct: 831 RNNKEIG-GGLEAEVTVYANDEYRALLAQLGNELRFVLITSKVDVKSLSEKPADLADS-- 887
Query: 937 LTVEIDGKTFHLTREHIIVEEKLP 960
E++G +TR + EK P
Sbjct: 888 ---ELEGIAVSVTRSN---AEKCP 905
>dbj|BAB10327.1| (AB017061) isoleucyl-tRNA synthetase [Arabidopsis thaliana]
Length = 988
Score = 432 bits (1100), Expect = e-120
Identities = 291/865 (33%), Positives = 441/865 (50%), Gaps = 95/865 (10%)
Query: 16 EEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRTM 75
E +++K W EN+++++V + +G + DGPPY +G +H+G A NKI+KD+I R++ +
Sbjct: 38 EPELQKLWEENQVFKRVSD-NNNGGSFILHDGPPYANGDLHMGHALNKILKDIINRYKLL 96
Query: 76 QGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIMTE 135
Q Y V PG+D HGLPIE+KV Q+L + +KE+ K +FA +K E
Sbjct: 97 QNYKVQYVPGWDCHGLPIELKVLQSLDQEVRKELTPL----KLRAKAAKFAKATVKTQME 152
Query: 136 QFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHE 195
FK G+W DW+NPY+T+ EY + + KG + + ++ +HW P TALAE E
Sbjct: 153 SFKRFGVWADWNNPYLTLDPEYEAAQIEVFGQMALKGYIYRGRKPVHWSPSSRTALAEAE 212
Query: 196 VRGEY-KLRKDPSIYVKFPVEGK----------ENEYLLIWTTTPWTLPANLAVSAHPDY 244
+ EY + SIY F + G N YL +WTTTPWT+PAN AV+ +
Sbjct: 213 L--EYPEGHISKSIYAIFKLVGGAKTSLLDEFIPNIYLAVWTTTPWTMPANAAVAVNAKL 270
Query: 245 DYVKVKVE-FNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYP 303
Y V+V+ FN ++ + I+A LV + + GVK + + F G +LE RY H + +
Sbjct: 271 QYSVVEVQSFNQQKLFVIVATDLVPALEAKWGVKLSISKTFLGSDLENCRYTHPIDNRD- 329
Query: 304 RQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGK 363
VI D++T E GTGLVHTAPGHG+ED+ G KYGLP+ SP+DD+GK
Sbjct: 330 -----------CPVVIGGDYITTESGTGLVHTAPGHGQEDYATGLKYGLPLVSPVDDEGK 378
Query: 364 YTE--GKWKGIYV-KEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWF 420
+TE G+++G+ V E + ++ +L E LV HKYP+ WR K P IFRAT+QWF
Sbjct: 379 FTEEAGQFRGLSVLGEGNTAVVSYLDENMSLVMEESYAHKYPYDWRTKKPTIFRATEQWF 438
Query: 421 LKISKVKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGE 480
+ + + + V W P R DW ISRQR WG+P+P +
Sbjct: 439 ASVEGFRTATM-DAINNVKWVPHQAVNRISAMTSSRSDWCISRQRTWGVPIPAF------ 491
Query: 481 IYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNG 540
Y V + L +N E I +S +I +K + D K
Sbjct: 492 -YHVKTKEPL--------MNEETINHVKS------IISQKGSDAWWYMSVEDLLPEKYRD 536
Query: 541 K--DMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQA 598
K D + D +DVWFDSG +SWA + R F PAD +EG DQ WF S
Sbjct: 537 KAADYEKGTDTMDVWFDSG-SSWAGVLGKREGLSF----PADVYLEGTDQHRGWFQSSLL 591
Query: 599 ASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERA---------GRDTFR 649
SI PY V HG+VLDEKG KMSKSLGN++ P V+E G D R
Sbjct: 592 TSIATQGKAPYSAVITHGFVLDEKGMKMSKSLGNVVDPRLVIEGGKNSKDAPAYGADVMR 651
Query: 650 FYMLWATNPWENLKFSWKGVEQVRRMLNILWNV-----YVLASTY-MSLDNFDPRKLNPD 703
++ + L G + +R+M +I + Y+L + + +DN P +
Sbjct: 652 LWVSSVDYTGDVL----IGPQILRQMSDIYRKLRGTLRYLLGNLHDWRVDNAVPYQ---- 703
Query: 704 ELPFREEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWV 763
+LP D+ L ++ +++ ++ E++ K + + F + DLS +Y + + RL+
Sbjct: 704 DLPI--IDQHALFQLENVVKNIQECYENYQFFKIFQIIQRFTIVDLSNFYFDIAKDRLYT 761
Query: 764 EGEDPDKLAAYYTLWKVFDV-LLRLLAPFTPYIAEEIYQNLIRPFTN-----VESVHMLD 817
G + T+ + +LR++AP P++AE+++QNL + N E V L
Sbjct: 762 GGTSSFTRRSCQTVLSTHLLSILRVIAPIVPHLAEDVWQNLPFEYRNEDGSAAEFVFELK 821
Query: 818 WPKVDEKAIDEELEREMEFIRRIVE 842
WP ++E+ + E ++ F +R++E
Sbjct: 822 WPTLNEQWLSFPAE-DVLFWQRLLE 845
>sp|O26861|SYV_METTH VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|7437639|pir||E69202 valine--tRNA ligase (EC 6.1.1.9)
MTH767 - Methanobacterium thermoautotrophicum (strain
Delta H) >gi|2621857|gb|AAB85270.1| (AE000855)
valyl-tRNA synthetase [Methanobacterium
thermoautotrophicum]
Length = 897
Score = 420 bits (1068), Expect = e-116
Identities = 285/958 (29%), Positives = 459/958 (47%), Gaps = 130/958 (13%)
Query: 8 REYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKD 67
++Y+ K E K +K W E +IYR + K P+Y PPY +G+IH+G N + D
Sbjct: 28 KDYNHKN-EVKWQKKWQEEDIYRFIGSGTK--PRYIIDTPPPYPTGSIHMGHVLNWVYMD 84
Query: 68 MIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFAL 127
+I RF+ M+G++V G+D HGLP EVKVE+ +K + + E F + C E
Sbjct: 85 IIARFKRMRGFDVLFPQGWDCHGLPTEVKVEETHNIK-----KSDVSREEFRRLCVELTQ 139
Query: 128 NNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRC 187
N+++M EQ + LG DW++ ++T+ EY+ + R + GL+ + ++WCPRC
Sbjct: 140 ENIRMMKEQMQRLGFSQDWNHEFVTMTPEYMRRTQLSFLRMYRDGLIYQGVHPVNWCPRC 199
Query: 188 ETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYV 247
ETA+A EV EY + YV+FPVEG + E++ I TT P + A +AV HPD +
Sbjct: 200 ETAIAFAEV--EYIENETNLNYVRFPVEGAD-EHITIATTRPELMAACVAVVVHPDDERF 256
Query: 248 KVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKE 307
+ EF DK++ E+ + G+ V+ K E++
Sbjct: 257 R---EFE-------------DKLI-EVPLFGQKVKLIKDPEVDP---------------- 283
Query: 308 FKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTE- 366
E GTG V + D ++GL V +D++G TE
Sbjct: 284 -------------------EFGTGAVMVCTFGDKTDVSWVNRHGLDVIDAIDERGYMTEA 324
Query: 367 -GKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISK 425
GK++G+ + E KI+E L +G+L+K + CWRCKTP+ QWF+ + K
Sbjct: 325 AGKYQGLTIAECKEKIVEDLENEGFLLKKEPVRQNVGTCWRCKTPIEILVKKQWFVAVKK 384
Query: 426 VKDKIIKENDEKVTWYPDWVKIRFDNGVRD-SGDWVISRQRYWGIPLPIWQ-SEDGEIYV 483
+ + ++E E++ W P +K R N DW ISRQR + P+P+W SE G ++V
Sbjct: 385 LIPQ-VREAAEEMKWVPGHMKTRLLNWTGSMDWDWCISRQRIFATPIPVWYCSECGRVHV 443
Query: 484 VGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDM 543
EE L V + GP + +
Sbjct: 444 AD-------------------------EEMLPVDPTRDGP---------GITCECGSTEF 469
Query: 544 RRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVA 603
+DV+D W DS I+ + G+P E + +L+PAD +G D + W + +
Sbjct: 470 IGEEDVLDTWMDSSISPLSVAGWP--DESYRELFPADLRPQGHDIIRTWAFYTILRCMAL 527
Query: 604 FDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATN--PWEN 661
P+ + ++G V E G KMSKS GN+I PEEV+E G D R LWA P +
Sbjct: 528 TGEKPFSEIVINGMVFGEDGHKMSKSRGNVIAPEEVLEDYGADALR---LWAAGSVPGSD 584
Query: 662 LKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSL 721
+ F+WK V+ + L WN + S +++ NP E+ R D+WILSR+ +L
Sbjct: 585 VPFAWKDVKYGYKFLRKFWNAFRFISIHLT--------ENP-EVEARPMDRWILSRLMNL 635
Query: 722 ISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVF 781
++EV ++ + A + F+ D Y+ ++ RL+ + + ++AA TL V
Sbjct: 636 VAEVTESLDDYNFAAAVNRVQTFIWHDFCDEYIEAVKYRLYSDEDPESRMAAQNTLRMVL 695
Query: 782 DVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREMEFIRRIV 841
D LRLLAP P+ EE++Q++ S+H+ WP+ + +D E+ER + I+
Sbjct: 696 DTCLRLLAPVAPHFTEEVHQHV-----GEGSIHLRGWPEHIPEIVDPEIERSGDLAVEII 750
Query: 842 EAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQLNAKEV-----KVGRV 896
+ +K+ L P++ I T++E+ + L+ I +N ++ K
Sbjct: 751 GEIRRFKSSSKMPLNAPLKAATIYTDNESAEMIKPFLDDI-AGTMNIGDISLVAGKPEIT 809
Query: 897 ERELTIKPNFAKLGPEFKGDAKIIAKWI-NENGRELYEKGELTVEIDGKTFHLTREHI 953
ER + ++P K+GPEF+ DA I W+ + E+YE+ + EI+ + LT +HI
Sbjct: 810 ERAVELEPRMEKIGPEFRSDAPAIISWLTGADPHEVYEEIQRNGEIEVEGNRLTMDHI 867
>gb|AAC41448.1| (L37104) transfer RNA-Ile synthetase [Thermotoga maritima]
Length = 505
Score = 420 bits (1067), Expect = e-116
Identities = 235/562 (41%), Positives = 326/562 (57%), Gaps = 75/562 (13%)
Query: 87 DMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIMTEQFKMLGIWMDW 146
D HGLPIE +V Q LG K K+ +I KKC+EFAL + I E+FK LG+ DW
Sbjct: 1 DTHGLPIEHRVSQELGEKIKEMSPAEIR-----KKCEEFALRFVDIQREEFKRLGVRGDW 55
Query: 147 DNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHEVRGEYKLRKDP 206
+NPY+T+K +Y K E+G + + + ++WCPRC TALAE E+ EY K P
Sbjct: 56 ENPYITLKPDYEVKILDVFKTLVEQGNVYRSLKPIYWCPRCRTALAEAEI--EYHDHKSP 113
Query: 207 SIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVKVKVEFNGREEYWILAKAL 266
SIYVKF + N +++IWTTTPWTLPAN+ ++ HPDY+Y VKV EE W++A L
Sbjct: 114 SIYVKFRSKEDPNFFIVIWTTTPWTLPANVGIALHPDYEYSVVKVG----EEKWVIATDL 169
Query: 267 VDKVLGEIGVK-GEVVEEFKGRELEGLRYVHILMDEYPRQKEFKEKYEWAHRVILADFVT 325
+D E G+ VVE+ KG++LEG +VH + D+ RVILAD+V+
Sbjct: 170 LDAFSKETGIDCSNVVEKIKGKDLEGKEFVHPIFDDR------------TSRVILADYVS 217
Query: 326 LEEGTGLVHTAPGHGEEDFEVGQ-KYGLPVYSPLDDQGKYTE--GKWKGIYVKEADPKII 382
LE GTG VH APGHGEED+ G +YGLP+ SP+D++G++TE GK+KG+++++A+ II
Sbjct: 218 LETGTGCVHIAPGHGEEDYIYGHVQYGLPIVSPVDEEGRFTEEAGKYKGMFIEDANEVII 277
Query: 383 EHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKI--SKVKDKIIKENDEKVTW 440
E L+ KG LV A I H YPHCWRCK P+IFRAT+QWF+ + + ++ K+++E D KV W
Sbjct: 278 EDLKRKGILVHASSITHSYPHCWRCKGPVIFRATEQWFISVDHNNLRQKVLEEID-KVKW 336
Query: 441 YPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVELAVAIEVN 500
P+W + R + V + DW ISRQR WG P+P AV +
Sbjct: 337 IPEWGRNRIRSMVEERPDWCISRQRVWGTPIP---------------------AVKCKEC 375
Query: 501 GERIELPESYEEKLKVIE------------EKLGPEDLHRPYVDAFIIKVNGKDMRRVKD 548
GE + P+ E +K++E E+L PED P K + ++ D
Sbjct: 376 GEVVLDPKVIEHFMKIVEKEGTNAWFEKEVEELIPEDFVCP-------KCGKRSFEKMLD 428
Query: 549 VVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVAFDTVP 608
+DVW DSG AS Y K + +P D +EG DQ WF+S ++ + P
Sbjct: 429 TLDVWIDSG----ASFEYITTKR-EDHPFPLDMYLEGSDQHRGWFHSSIFLAVAKRGSAP 483
Query: 609 YRRVAMHGYVLDEKGDKMSKSL 630
Y+ V HG++ DE+G KMSKSL
Sbjct: 484 YKEVLTHGFIKDEQGRKMSKSL 505
>sp|Q58413|SYV_METJA VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|2129352|pir||F64425 valine--tRNA ligase (EC 6.1.1.9)
- Methanococcus jannaschii >gi|1591666|gb|AAB99009.1|
(U67543) valyl-tRNA synthetase (valS) [Methanococcus
jannaschii]
Length = 878
Score = 418 bits (1062), Expect = e-115
Identities = 289/931 (31%), Positives = 454/931 (48%), Gaps = 120/931 (12%)
Query: 14 KLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFR 73
++E++++K W E++IY+ +E K P Y PPY +G +HLG A N D+I R++
Sbjct: 10 EIEKQIQKKWEESKIYKFDEESNK--PPYIIDTPPPYPTGRLHLGHALNWTYMDIIARYK 67
Query: 74 TMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIM 133
M+G+NV G+D HGLP EVKVE+ G+ TK +++ F + C E N++ M
Sbjct: 68 RMKGFNVLFPQGWDCHGLPTEVKVEEIHGI-TKSDVDR----HKFRELCIELTKENIEKM 122
Query: 134 TEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAE 193
Q K LGI +DWD Y+T+ EYI+ + R ++ GL+ + K ++WCPRC+TA+A
Sbjct: 123 RRQIKSLGISIDWDKEYITMTPEYIKKSQTAFVRMYKDGLIYRGKFPVNWCPRCQTAIAF 182
Query: 194 HEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVKVKVEF 253
EV EYK R+ Y+KFP E +LLI TT P + A +A+ HP+ + K
Sbjct: 183 AEV--EYKERESKLNYIKFPAADGEG-HLLIATTRPELMAACVAILVHPEDERYK----- 234
Query: 254 NGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFKEKYE 313
++ K + + G V +L DE +KEF
Sbjct: 235 ------HLIGKEFIVPLFGH--------------------KVKLLADE-DVEKEF----- 262
Query: 314 WAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTE--GKWKG 371
GTG V + D ++ L + +D++G+ TE GK+KG
Sbjct: 263 ---------------GTGAVMVCTFGDKTDVLWVNRHKLEIKKAIDEKGELTEIAGKYKG 307
Query: 372 IYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKDKII 431
+ +EA KIIE L+++GYLVK I+ CWRCKTP+ T+QWF+ + K+ K+
Sbjct: 308 LKTEEAREKIIEDLKKEGYLVKQEPIKQNVGVCWRCKTPIEIIVTEQWFVNVRKLIPKVR 367
Query: 432 KENDEKVTWYPDWVKIRFDNGVRDSG-DWVISRQRYWGIPLPIWQSEDGEIYVVGSWREL 490
+ DE + W P+ +KIR N + D DWVISRQR + P+P+W VV
Sbjct: 368 EVADE-IKWIPEHMKIRLLNWIEDMDWDWVISRQRIFATPIPVWYCPKCGNVVVAK---- 422
Query: 491 VELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVV 550
EE L + K G YV K KD+ DV+
Sbjct: 423 --------------------EEDLPIDPTKTG-------YV---CDKCGNKDLIPETDVL 452
Query: 551 DVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVAFDTVPYR 610
D W DS I + + + FEK +P +G D + W + S+ P+
Sbjct: 453 DTWMDSSITPMVITKWLDDDKFFEKHYPVQLRPQGHDIIRTWAFYTIVKSVALTGKKPWD 512
Query: 611 RVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNP--WENLKFSWKG 668
+ ++G V E G KMSKS GN++ P+E++ + G D R LWA+N ++++F WK
Sbjct: 513 EIVINGMVFGEDGHKMSKSRGNVVEPDEIIAKYGADALR---LWASNSVVGDDVQFLWKE 569
Query: 669 VEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISEVENG 728
V+ R L WN A ++S D D K P E+ D WILS++ LI V+
Sbjct: 570 VDYGYRFLRKSWNACRFAKMHISDDIIDELK-KPMEIS-NPIDLWILSKLQRLIERVDKD 627
Query: 729 IESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFDVLLRLL 788
+E++ +Y FV + Y+ +++ RL+ + E+ K A +TL+ V D ++RLL
Sbjct: 628 LENYRFNTIVE-IYKFVWHEFCDNYIEMVKYRLYGDDEEAKK-EARWTLYYVIDKVVRLL 685
Query: 789 APFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREMEFIRRIVEAGSAAR 848
PF P+ + + I ++++H +P+VD + I+EE E+ E + V + +
Sbjct: 686 CPFAPH-----FSDYIAEIYKIDNLH-FSFPEVDNRFINEEAEKFGEIAKNTVISIRRFK 739
Query: 849 QRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQLNAKEVKVGRVERELTIK----- 903
+ + L P++ + I TEDE A+ + ++ L +E+K+ + + L K
Sbjct: 740 ANSGMALNAPLKYVEIYTEDEETYLALNKTAEDIKGTLKIEELKIIKGKPALESKIVEII 799
Query: 904 PNFAKLGPEFKGDAKIIAKWINENGRELYEK 934
P+ +K+GPEFK +AK + I E EK
Sbjct: 800 PDKSKIGPEFKKNAKAVMDLIKNADEETLEK 830
>sp|P57249|SYI_BUCAI ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|10038832|dbj|BAB12867.1| (AP001118) isoleucyl-tRNA
synthetase [Buchnera sp. APS]
Length = 940
Score = 416 bits (1058), Expect = e-115
Identities = 259/827 (31%), Positives = 439/827 (52%), Gaps = 78/827 (9%)
Query: 14 KLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFR 73
K E + K W+EN +Y+ +++ ++ ++ DGPPY +G IH+G A NKI+KD+II+ +
Sbjct: 23 KKEPNILKSWNENNLYKLIRKKNQEKKIFFLHDGPPYANGNIHIGHAVNKILKDIIIKSK 82
Query: 74 TMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIM 133
M G++ P +D HGLPIE KVE+ + K + +I F +KC+++A + ++
Sbjct: 83 NMSGFDAPYIPSWDCHGLPIEQKVEEKI-----KSNQGEISTTEFQEKCRKYAQDQVEKQ 137
Query: 134 TEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAE 193
+ F LG+ DWDNP++T+ + + TL + +K L +D + +HWC +C ++L+E
Sbjct: 138 KKDFIRLGVIGDWDNPHLTMNFKNEANIIKTLSKIVQKKHLYQDFKPIHWCLKCASSLSE 197
Query: 194 HEVRGEYKLRKDPSIYV--------------KFPVEGKENEYLLIWTTTPWTLPANLAVS 239
E+ EY +K SI V F + K+ +LLIWTTTPWTLP++ A+S
Sbjct: 198 AEI--EYSKKKSDSIIVGFKFKYKSIIEKLFDFQISNKKEIHLLIWTTTPWTLPSSKAIS 255
Query: 240 AHPDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEF-KGRELEGLRYVHIL 298
HPD+ Y ++ E Y I+AK LV+K L + +K ++ + KGR LE + +H
Sbjct: 256 IHPDFQYQLIETE----RCYLIIAKELVEKTLNTLKIKKSIIRNYVKGRFLEKMICLHPF 311
Query: 299 MDEYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPL 358
+ VIL VTLE GTG VHTAP HG ED+ + QKY + + +
Sbjct: 312 LKNIDLP------------VILGKHVTLESGTGAVHTAPDHGLEDYIISQKYNIKTSNIV 359
Query: 359 DDQGKY---TEGKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRA 415
+ +G+Y T K G+ V EA+ IIE L + + H YPHCWR K+P+I+RA
Sbjct: 360 NFKGEYISNTHDKLDGVNVLEANSIIIELLIKNNTFFHHESLIHSYPHCWRHKSPVIYRA 419
Query: 416 TDQWFLKISKVKDKI-IKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIW 474
T QWF+ I + + +I + + +KV W P+W + R ++ DW ISRQR WG+P+ I+
Sbjct: 420 TPQWFIDIDQKQLRIKLLQEIKKVRWIPEWGESRIGEMIKKRPDWCISRQRKWGVPMSIF 479
Query: 475 QSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAF 534
++ ++ + ++A +E+ G +++ + + K E LG E ++ Y
Sbjct: 480 IHKNTRKIHPNTFVFMKKIAKKVELEG--LQVWWNIDSK-----EILGEE--YQSY---- 526
Query: 535 IIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFY 594
++ D++DVWF+SG + ++ Y +NK +K AD +EG DQ WF
Sbjct: 527 ---------EKILDILDVWFESG-NTHTTINY-KNKNYTKK--NADMFLEGSDQHRGWFM 573
Query: 595 SQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLW 654
S S + + PY V HG+V+D KG KMSKS+GN I P E+V+ G D R ++
Sbjct: 574 SSLIISTLISEKKPYSEVLTHGFVVDGKGQKMSKSIGNTISPNEIVDTLGADILRLWVA- 632
Query: 655 ATNPWENLKFSWKGVEQVRRMLNILWNV--YVLASTYMSLDNFDPRKLNPDELPFREEDK 712
++N ++ S + ++ + + N ++LA ++ +FDP+K + DK
Sbjct: 633 SSNYSNDISISNEILKSSSDIYRRIRNTARFMLA----NISDFDPKKNIISKENMVLLDK 688
Query: 713 WILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLW-VEGEDPDKL 771
W + + + E+ ++ + L F ++ +Y+ +I+ R + ++ ++
Sbjct: 689 WAIGQTKIVQEEIIQHYNNYNFHAVIQRLMYFCSIEMGSFYLDIIKDRQYTLKKHSQERR 748
Query: 772 AAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDW 818
++ ++ + + L+R +AP + A+EI+ L P N + V M +W
Sbjct: 749 SSQTAIYYIINSLVRWIAPILSFTADEIWSYL--PENNSQYVFMEEW 793
>sp|Q9ZHB3|SYI_STRPN ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|4009476|gb|AAC95446.1| (AF068901) isoleucine-tRNA
synthetase [Streptococcus pneumoniae]
Length = 930
Score = 416 bits (1057), Expect = e-115
Identities = 291/894 (32%), Positives = 464/894 (51%), Gaps = 80/894 (8%)
Query: 20 EKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRTMQGYN 79
+K W + ++Y++ +EL + P + DGPPY +G IH+G A NKI KD+I+R ++M G+
Sbjct: 28 QKEWEDAKLYQRRQELNQGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFY 87
Query: 80 VWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIMTEQFKM 139
PG+D HGLPIE +V G+K K ++ + ++K C+E+AL+ + E FK
Sbjct: 88 APFIPGWDTHGLPIE-QVLSKQGVKRK-----EMDLVEYLKLCREYALSQVDKQREDFKR 141
Query: 140 LGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHEVRGE 199
LG+ DW+NPY+T+ +Y + KG + + + ++W E+ALAE E+ E
Sbjct: 142 LGVSGDWENPYVTLTPDYEAAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEI--E 199
Query: 200 YKLRKDPSIYVKFPV-EGK----ENEYLLIWTTTPWTLPANLAVSAHPDYDYVKVKVEFN 254
Y S+Y V +GK + Y+++WTTTP+T+ A+ ++ D DYV V+
Sbjct: 200 YHDLVSTSLYYANKVKDGKGVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPV-- 257
Query: 255 GREEYWILAKALVDKVLGEIG-VKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFKEKYE 313
G +++A L+ + + G +V+E ++G+EL HI + E+P +E
Sbjct: 258 GEARKFVVAAELLTSLSEKFGWADVQVLETYRGQELN-----HI-VTEHPWDTAVEE--- 308
Query: 314 WAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQG---KYTEGKWK 370
VIL D VT + GTG+VHTAPG GE+D+ VG L V +D++G K +++
Sbjct: 309 ---LVILGDHVTTDSGTGIVHTAPGFGEDDYNVGIANNLEVAVTVDERGIMMKNAGPEFE 365
Query: 371 GIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKDKI 430
G + ++ P +IE L L+ EI H YP WR K P+I+RA QWF +SK + +I
Sbjct: 366 GQFYEKVVPTVIEKL--GNLLLAQEEISHSYPFDWRTKKPIIWRAVPQWFASVSKFRQEI 423
Query: 431 IKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWREL 490
+ E EKV ++ +W K+R N +RD GDWVISRQR WG+PLPI+ +EDG +V E
Sbjct: 424 LDE-IEKVKFHSEWGKVRLYNMIRDRGDWVISRQRTWGVPLPIFYAEDGTAIMVAETIE- 481
Query: 491 VELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVV 550
+A E +G I ++ L PE P NG + ++ D++
Sbjct: 482 -HVAQLFEKHGSSIWWERDAKDLL--------PEGFTHPG------SPNG-EFKKETDIM 525
Query: 551 DVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVAFDTVPYR 610
DVWFDSG +SW + R E +PAD +EG DQ WF S S+ PY+
Sbjct: 526 DVWFDSG-SSWNGVVVNRP----ELTYPADLYLEGSDQYRGWFNSSLITSVANHGVAPYK 580
Query: 611 RVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWAT--NPWENLKFSWKG 668
++ G+ LD KG+KMSKSLGN I P +V ++ G + R LW T + +++ S
Sbjct: 581 QILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILR---LWVTSVDSSNDVRISMDI 637
Query: 669 VEQVRRMLNILWNV--YVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISEVE 726
+ QV + N +++A+T +F+P + R DK++ R N L+ +
Sbjct: 638 LSQVSETYRKIRNTLRFLIANT----SDFNPAQDTVAYDELRSVDKYMTIRFNQLVKTIR 693
Query: 727 NGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFDVLL- 785
+ F +AL NF+ DLS +Y+ + +++EG + T++ +D+L+
Sbjct: 694 DAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQMQTVF--YDILVK 751
Query: 786 --RLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEEL----EREMEFIRR 839
+LL P P+ AEEI+ L F + V + + P+V A EE+ M+F +
Sbjct: 752 ITKLLTPILPHTAEEIWSYL--EFETEDFVQLSELPEVQTFANQEEILDTWAAFMDFRGQ 809
Query: 840 IVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQLNAKEVKV 893
+A AR AK+ + + + +E VK +E +N + L E+ +
Sbjct: 810 AQKALEEAR-NAKV-IGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIVSELTI 861
>sp|P00956|SYI_ECOLI ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|7428465|pir||SYECIT isoleucine--tRNA ligase (EC
6.1.1.5) - Escherichia coli >gi|2367096|gb|AAC73137.1|
(AE000113) isoleucine tRNA synthetase [Escherichia coli
K12]
Length = 938
Score = 412 bits (1048), Expect = e-113
Identities = 270/816 (33%), Positives = 427/816 (52%), Gaps = 86/816 (10%)
Query: 11 DPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMII 70
D K E + W+++++Y ++ +K + DGPPY +G+IH+G + NKI+KD+I+
Sbjct: 20 DLAKREPGMLARWTDDDLYGIIRAAKKGKKTFILHDGPPYANGSIHIGHSVNKILKDIIV 79
Query: 71 RFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNL 130
+ + + GY+ PG+D HGLPIE+KVEQ G + EK F KC+E+A +
Sbjct: 80 KSKGLSGYDSPYVPGWDCHGLPIELKVEQEYG-----KPGEKFTAAEFRAKCREYAATQV 134
Query: 131 KIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETA 190
+ F LG+ DW +PY+T+ + + L + G L K + +HWC C +A
Sbjct: 135 DGQRKDFIRLGVLGDWSHPYLTMDFKTEANIIRALGKIIGNGHLHKGAKPVHWCVDCRSA 194
Query: 191 LAEHEVRGEYKLRKDPSIYV------------KFPVEGKENEY-LLIWTTTPWTLPANLA 237
LAE EV EY + PSI V KF V L+IWTTTPWTLPAN A
Sbjct: 195 LAEAEV--EYYDKTSPSIDVAFQAVDQDALKAKFAVSNVNGPISLVIWTTTPWTLPANRA 252
Query: 238 VSAHPDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKG-EVVEEFKGRELEGLRYVH 296
+S PD+DY V+++ + ILAK LV+ V+ IGV ++ KG ELE LR+ H
Sbjct: 253 ISIAPDFDYALVQID----GQAVILAKDLVESVMQRIGVTDYTILGTVKGAELELLRFTH 308
Query: 297 ILMD-EYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVY 355
M + P IL D VTL+ GTG VHTAPGHG +D+ +GQKYGL
Sbjct: 309 PFMGFDVP--------------AILGDHVTLDAGTGAVHTAPGHGPDDYVIGQKYGLETA 354
Query: 356 SPLDDQGKYTEGKW---KGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLI 412
+P+ G Y G + G+ V +A+ ++ L+EKG L+ +++H YP CWR KTP+I
Sbjct: 355 NPVGPDGTYLPGTYPTLDGVNVFKANDIVVALLQEKGALLHVEKMQHSYPCCWRHKTPII 414
Query: 413 FRATDQWFLKISK--VKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIP 470
FRAT QWF+ + + ++ + +KE + V W PDW + R ++ V + DW ISRQR WG+P
Sbjct: 415 FRATPQWFVSMDQKGLRAQSLKE-IKGVQWIPDWGQARIESMVANRPDWCISRQRTWGVP 473
Query: 471 LPIWQSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPY 530
+ ++ +D E + + E+A +EV+G I+ + K E LG E
Sbjct: 474 MSLFVHKDTEELHPRTLELMEEVAKRVEVDG--IQAWWDLDAK-----EILGDE------ 520
Query: 531 VDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVT 590
D ++ +V D +DVWFDSG ++ +S+ R + AD +EG DQ
Sbjct: 521 ADQYV---------KVPDTLDVWFDSG-STHSSVVDVRPEFAGH---AADMYLEGSDQHR 567
Query: 591 KWFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRF 650
WF S S PYR+V HG+ +D +G KMSKS+GN + P++V+ + G D R
Sbjct: 568 GWFMSSLMISTAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQDVMNKLGADILRL 627
Query: 651 YMLWATNPWE---NLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRK--LNPDEL 705
++ E + + + + RR+ N ++LA +L+ FDP K + P+E+
Sbjct: 628 WVASTDYTGEMAVSDEILKRAADSYRRIRNTA--RFLLA----NLNGFDPAKDMVKPEEM 681
Query: 706 PFREEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLW-VE 764
D+W + + ++ E++ + + L F ++ +Y+ +I+ R + +
Sbjct: 682 VVL--DRWAVGCAKAAQEDILKAYEAYDFHEVVQRLMRFCSVEMGSFYLDIIKDRQYTAK 739
Query: 765 GEDPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIY 800
+ + + L+ + + L+R +AP + A+E++
Sbjct: 740 ADSVARRSCQTALYHIAEALVRWMAPILSFTADEVW 775
>pir||D71457 valine--tRNA ligase (EC 6.1.1.9) - Pyrococcus horikoshii
>gi|3256704|dbj|BAA29387.1| (AP000001) 896aa long
hypothetical valyl-tRNA synthetase [Pyrococcus
horikoshii]
Length = 896
Score = 411 bits (1045), Expect = e-113
Identities = 305/977 (31%), Positives = 467/977 (47%), Gaps = 134/977 (13%)
Query: 8 REYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKD 67
+ YDP ++E K +K+W E +IY+ L ++ P Y PP+ SG +HLG + D
Sbjct: 9 KNYDPNEIEPKWQKYWLEEKIYKY--RLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWID 66
Query: 68 MIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFAL 127
+I R++ M+GYNV G+D HGLP E+KVE+ G+ TK + EE F+KKC E+
Sbjct: 67 IIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGI-TKDQPEE------FLKKCVEWTW 119
Query: 128 NNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRC 187
++ M +QF +G DWD Y T+ + Y + +L ++KGL+ +++ ++WCP+C
Sbjct: 120 QAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQRSLLEFYKKGLIYREEHPVYWCPKC 179
Query: 188 ETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYV 247
T+LA+ EV Y + Y+K P+ Y+ I TT P +PA +AV HPD
Sbjct: 180 RTSLAKAEVG--YVEEEGYLYYIKLPLADGSG-YIPIATTRPELMPACVAVFVHPD---- 232
Query: 248 KVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKE 307
E Y K LV K VK + E R V IL DE
Sbjct: 233 --------DERY----KHLVGKK-----VKLPIFE----------REVPILADED----- 260
Query: 308 FKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTE- 366
V GTG V+ E+D ++Y LPV +++ G E
Sbjct: 261 ----------------VDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIVINEDGTMNEN 304
Query: 367 -GKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKY-PHCWR--CKTPLIFRATDQWFLK 422
G + G+ ++EA KI E L + G L K +I+H+ H R C P+ QWF+K
Sbjct: 305 AGPYAGLKIEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIK 364
Query: 423 ISKVKDKIIKENDEKVTWYPDWVKIRFDNGVRDSG-DWVISRQRYWGIPLPIWQSEDGEI 481
+ + D+IIK E + WYP+ + +R + DWVISRQR +G P P W ++G I
Sbjct: 365 VKDLIDEIIKVAKE-INWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGHI 423
Query: 482 YVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGK 541
+ EE L V +P VD V G
Sbjct: 424 I-------------------------PAREEDLPVDPR------FDKPPVDK--CPVCGA 450
Query: 542 DMRRVKDVVDVWFDSGIA-----SW--ASLGYPRNKELFEKLWPADFIVEGEDQVTKWFY 594
++ V DV+D W DS I W A G K+ FE +P +G D + W +
Sbjct: 451 EIEPVTDVLDCWVDSSITPLIITKWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAF 510
Query: 595 SQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLW 654
+ V P++ + ++G V G KMSKS GN++ PEEV+ + G D R +
Sbjct: 511 YTILRTYVLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVSPEEVIPKYGADALRLWTAL 570
Query: 655 ATNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWI 714
A P E+ F W+ V+ R L +WN+Y A ++ +FD K EL DKWI
Sbjct: 571 AP-PGEDHPFKWETVDYNYRFLQKVWNIYRFAERHIK--DFDYEKYRDVEL--EPLDKWI 625
Query: 715 LSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAY 774
LSR++ +I +E + TR L F+ +++ Y+ +I+ RL+ E E+ KL A
Sbjct: 626 LSRLHRIIKFATEELERYRFNLITRELITFIWHEVADDYIEMIKYRLYGEDEE-SKLKAK 684
Query: 775 YTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREM 834
L+++ ++ LLAPF P+I EEIY + + +SVH+L WP+ E IDEE E+
Sbjct: 685 VALYELLYNVMLLLAPFVPHITEEIYHAIFKEKIGEKSVHLLSWPEYREDRIDEEAEKIG 744
Query: 835 EFIRRIVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRD---QLNAKEV 891
E R+IV + + L ++ + I D + ERL I RD +N + +
Sbjct: 745 ELARKIVSEMRKYKNSHGLPLNAKLKHVAIYALD-----SYERLKLIERDIAGTMNIERL 799
Query: 892 KVGR-----VERELTIKPNFAKLGPEFKGDAKIIAKWINENG----RELYEKGELTVEID 942
++ + ER + +KPN+ +GP++ I +++ EN RE+ EKG+ E++
Sbjct: 800 EIVKGEPHLEERIVEVKPNYKNIGPKYGKLVPRIVQYLRENAESIVREIKEKGKAEFEVE 859
Query: 943 GKTFHLTREHIIVEEKL 959
GK LT+E I V +++
Sbjct: 860 GKKVELTKEDITVRKEV 876
>pir||B83077 isoleucyl-tRNA synthetase PA4560 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9950805|gb|AAG07948.1|AE004869_12 (AE004869)
isoleucyl-tRNA synthetase [Pseudomonas aeruginosa]
Length = 943
Score = 410 bits (1042), Expect = e-113
Identities = 273/854 (31%), Positives = 428/854 (49%), Gaps = 101/854 (11%)
Query: 16 EEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRTM 75
E + KFW++ +Y+K++ + D PK+ DGPPY +G+IH+G A NKI+KD+I+R +T+
Sbjct: 25 EPETLKFWNDIGLYQKLRAIGGDRPKFVLHDGPPYANGSIHIGHAVNKILKDIIVRSKTL 84
Query: 76 QGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIMTE 135
GY+ PG+D HGLPIE KVE G + + + + C+E+A ++
Sbjct: 85 AGYDAPYVPGWDCHGLPIEHKVETTHG--------KNLPADKTRELCREYAAEQIEGQKA 136
Query: 136 QFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHE 195
F LG+ +WDNPY T+ + L ++ + K + ++WC C +ALAE E
Sbjct: 137 DFIRLGVLGEWDNPYKTMNFANEANEIRALAEMVKQDFVFKGLKPVNWCFDCGSALAEAE 196
Query: 196 VRGEYKLRKDPSIYVKFPVEGKEN-------------EYLLIWTTTPWTLPANLAVSAHP 242
V EY +K P+I V FPV + ++IWTTTPWT+PAN A++ HP
Sbjct: 197 V--EYADKKSPTIDVGFPVADADKLAAAFGLAALDKPAQIVIWTTTPWTIPANQALNVHP 254
Query: 243 DYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEY 302
+ DY V + + Y +LA+ALV+ L +G+VV KG LE + + H
Sbjct: 255 EIDYALV----DAGDRYLVLAEALVESCLARYQREGKVVATAKGEALELINFRHPF---- 306
Query: 303 PRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGL---PVYSPLD 359
YE V LAD+V L+ GTG+VH++P +GE+DF ++YG+ + SP+
Sbjct: 307 ---------YERLSPVYLADYVALDAGTGIVHSSPAYGEDDFYTCKRYGMSNDDILSPVQ 357
Query: 360 DQGKYTEGK--WKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATD 417
G Y + + G ++ +A+P ++ L E G L+ I H Y HCWR KTPLI+RAT
Sbjct: 358 SNGVYVDSLPFFGGQFIWKANPNVVAKLEEVGSLLAHETINHSYMHCWRHKTPLIYRATA 417
Query: 418 QWFLKISK-------VKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIP 470
QWF+ + K ++++ + E + + P W + R + DW ISRQR WG+P
Sbjct: 418 QWFVGMDKQPRQGASLRERAL-EAITQTEFVPGWGQARLHGMIAGRPDWCISRQRNWGVP 476
Query: 471 LPIW-QSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKV-IEEKLGPEDLHR 528
+P + GE++ VEL +E +R+E E E K+ E LG E
Sbjct: 477 IPFFLHKASGELH-----PRTVEL---MEEVAQRVE-KEGIEAWFKLDAAELLGEE---- 523
Query: 529 PYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASL-GYPRNKELFEKLWPADFIVEGED 587
++ D +DVWFDSG W L G R + AD +EG D
Sbjct: 524 -----------AAQYEKINDTLDVWFDSGTTHWHVLRGSHRIGHASGPV--ADLYLEGSD 570
Query: 588 QVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDT 647
Q WF+S + PYR++ HG+ +DE G KMSKSLGN + P+ V++ G D
Sbjct: 571 QHRGWFHSSLLTGCAIDNHAPYRQLLTHGFTVDESGRKMSKSLGNTVVPQTVIDTLGADI 630
Query: 648 FRFYMLWATNPWE---NLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDE 704
R ++ E + + + + RR+ N ++L+ +L+ FDP D
Sbjct: 631 LRLWVASTDYSGEIAVSQQILQRSADAYRRIRNT--TRFLLS----NLNGFDPA---TDL 681
Query: 705 LPFREE---DKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRL 761
LP +E D+W + R L E+E + ++NF V++L +Y+ +I+ R
Sbjct: 682 LPPQEMLALDRWAVDRALLLQREIEEAYREYRFWNVYSKVHNFCVQELGGFYLDIIKDRQ 741
Query: 762 WVEGEDP-DKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDW-P 819
+ G + + + L+ + + L+R +AP + AEE+++ L P ESV + W
Sbjct: 742 YTTGANSVARRSCQTALFHIAEALVRWIAPILAFTAEEVWKFL--PGERAESVMLATWYD 799
Query: 820 KVDEKAIDEELERE 833
++E D L R+
Sbjct: 800 GLNELPADVTLNRQ 813
>pir||D82293 isoleucyl-tRNA synthetase VC0682 [imported] - Vibrio cholerae
(group O1 strain N16961) >gi|9655121|gb|AAF93847.1|
(AE004154) isoleucyl-tRNA synthetase [Vibrio cholerae]
Length = 949
Score = 406 bits (1033), Expect = e-112
Identities = 268/819 (32%), Positives = 420/819 (50%), Gaps = 86/819 (10%)
Query: 11 DPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMII 70
D K E ++ + W + ++Y +++ +K + DGPPY +G IH+G A NKI+KD+II
Sbjct: 20 DLAKREPEMLQRWYQEDLYGAIRQAKKGKKSFVLHDGPPYANGDIHIGHALNKILKDVII 79
Query: 71 RFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNL 130
+ +T+ G++ PG+D HGLPIE+ VE+ +G + +K+ F +KC+E+A +
Sbjct: 80 KSKTLSGFDAPYIPGWDCHGLPIELMVEKKVG-----KPGQKVTAAEFREKCREYAAGQV 134
Query: 131 KIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETA 190
+ E FK LGI +WD PY T+ + L + + G L K + +HWC C +A
Sbjct: 135 EGQKESFKRLGILGEWDKPYRTMDFVTEANIIRALGKIADNGHLLKGFKPVHWCTDCGSA 194
Query: 191 LAEHEVRGEYKLRKDPSIYVKFPV----------------EGKENEYLLIWTTTPWTLPA 234
LAE EV EYK + PSI V+F EGK + ++IWTTTPWTLPA
Sbjct: 195 LAEAEV--EYKNKVSPSIDVRFKAADEAAVLAKFGLAAGHEGKGDVSIVIWTTTPWTLPA 252
Query: 235 NLAVSAHPDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEF-KGRELEGLR 293
N AV D +YV ++VE + E I+A L V+ G++ F G +LE ++
Sbjct: 253 NRAVCLRADLEYVLIQVE-GEQPERIIVASELAKSVMDRAGIEHFHNLGFATGADLELVQ 311
Query: 294 YVHILMDEYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLP 353
+ H Y + IL D VT + GTG+VHTAPGHG+EDF VGQ+YGL
Sbjct: 312 FQHPF-------------YSFTVPAILGDHVTTDSGTGVVHTAPGHGQEDFAVGQQYGLE 358
Query: 354 VYSPLDDQGKYTEGK--WKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPL 411
V +P+ G Y + G +V +A+ ++E L+EKG L+ EH YPHCWR KTP+
Sbjct: 359 VANPVGSNGVYLPDTELFAGQHVFKANDSVLEVLKEKGALLHHHAYEHSYPHCWRHKTPI 418
Query: 412 IFRATDQWFLKISK--VKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGI 469
IFRAT QWF+ + + ++++ + + V W PDW + R + V +W ISRQR WG+
Sbjct: 419 IFRATPQWFVSMEQAGLREQALTA-IKGVHWMPDWGQSRIEGMVAGRPEWCISRQRTWGV 477
Query: 470 PLPIW-QSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHR 528
P+ ++ E E++ + +L+E VA V + I+ + E LG ED
Sbjct: 478 PIALFVHKETAELHPNSA--DLIE-KVAQLVEQKGIQAWWDLD-----TAELLGAED--- 526
Query: 529 PYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQ 588
+ +V D +DVWFDSG+ A + + E AD +EG DQ
Sbjct: 527 -----------AANYEKVLDTLDVWFDSGVTHSAVVDARQEFNGAE----ADMYLEGSDQ 571
Query: 589 VTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTF 648
WF S +S+ PY+ V HG+V+D +G KMSKS+GN++ P++V + G D
Sbjct: 572 HRGWFQSSLISSVAMKGKAPYKEVLTHGFVVDGQGRKMSKSIGNVVAPQDVTNKLGADIL 631
Query: 649 RFYMLWATNPWE---NLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDEL 705
R ++ E + + + + RR+ N + LA +L+ F+P D +
Sbjct: 632 RLWVASTDYTGEVAVSDEILKRSADAYRRIRNTA--RFFLA----NLNGFNP---TTDII 682
Query: 706 PFREE---DKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLW 762
P + D+W + R + E+ + + L + L NF ++ +Y+ +I+ R +
Sbjct: 683 PVEDMVALDRWAVGRALAAQQEIIQAYQDYNLHAVVQRLMNFCSIEMGSFYLDVIKDRQY 742
Query: 763 VEGEDPDKLAAYYT-LWKVFDVLLRLLAPFTPYIAEEIY 800
+ T L+ + + L+R +AP + A+EI+
Sbjct: 743 TAKRGGHAQRSCQTALFFIVEALVRWMAPIMSFTADEIW 781
>pir||C82559 isoleucyl-tRNA synthetase XF2418 [imported] - Xylella fastidiosa
(strain 9a5c) >gi|9107606|gb|AAF85217.1|AE004051_1
(AE004051) isoleucyl-tRNA synthetase [Xylella
fastidiosa]
Length = 943
Score = 405 bits (1030), Expect = e-111
Identities = 263/851 (30%), Positives = 418/851 (48%), Gaps = 107/851 (12%)
Query: 11 DPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMII 70
D K E + + W ++ Y +++ K P + DGPPY +G IHLG A NKI+KD+II
Sbjct: 21 DLPKREPAILERWERDDFYAQLRAHAKGRPLFLLHDGPPYANGQIHLGHAVNKILKDIII 80
Query: 71 RFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNL 130
+ + + G++ PG+D HGLPIE+ +E+ G ++ + F +KC+E+A +
Sbjct: 81 KSKHLDGFDAPYIPGWDCHGLPIEIAIEKKYG-----KVGVTLDAVQFRQKCREYAAEQI 135
Query: 131 KIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETA 190
++ FK LGI DWD PY T+ + L + +KG L + + +HWC C +A
Sbjct: 136 QLQRRDFKRLGIIGDWDAPYKTLDFRFEADEIRALAKIVDKGHLIRGTKPVHWCFDCGSA 195
Query: 191 LAEHEVRGEYKLRKDPSIYVKFP--------------VEGKENEYLLIWTTTPWTLPANL 236
LAE E+ EY + P + V +P + + IWTTTPWTLPA+L
Sbjct: 196 LAEAEI--EYTDKTSPMVDVAYPALDPSALAAVFNATLPPDVQLAVPIWTTTPWTLPASL 253
Query: 237 AVSAHPDYDYVKVK-VEFNGREEYWILAKALVDKVLGEIGVKGEVVE-EFKGRELEGLRY 294
A+S P DYV V+ +G+ + ILA+AL K L G+ ++ KG +E
Sbjct: 254 AISVGPTLDYVLVEGPTHSGQRRWLILAEALAAKALARYGIAELLIHGSAKGAAME---- 309
Query: 295 VHILMDEYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGL-- 352
HIL + + ++L + V+ E+GTG VHTAPGHG+ED +V Q+YGL
Sbjct: 310 QHILAHPFYPDRTIP--------LLLGNHVSAEDGTGAVHTAPGHGQEDHQVFQQYGLLN 361
Query: 353 ----PVYSPLDDQGKY-------TEGKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKY 401
+P+D +G Y +E G+++ +A+P I++ LR +G L+ A E+ H Y
Sbjct: 362 HYSAAELNPVDARGVYLPTTPPFSELTLAGLHIWKANPLIVDALRLRGVLLAAAEMHHSY 421
Query: 402 PHCWRCKTPLIFRATDQWFLKISK--VKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDW 459
PHCWR KTP++FRAT QWF+ + + ++ +K VTWYP W + R + + + DW
Sbjct: 422 PHCWRHKTPIVFRATPQWFISMEQAALRSAALKAITH-VTWYPQWGQARILSMIENRPDW 480
Query: 460 VISRQRYWGIPLPIWQSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEE 519
ISRQR WG+P+P++ S + ++A +E G +++ S ++ E
Sbjct: 481 TISRQRTWGVPIPLFVHRHSGAPHPRSAALMRQVADRVEQQG--VDIWYSLDQ-----TE 533
Query: 520 KLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASL---GYPRNKELFEKL 576
LG E ++ D++DVWFDSGI A L G P+
Sbjct: 534 LLGTE---------------ADQYEKITDILDVWFDSGITHEAVLLERGLPK-------- 570
Query: 577 WPADFIVEGEDQVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRP 636
PAD +EG DQ WF S + + PY++ HG+ +D+ G KMSKSLGN I P
Sbjct: 571 -PADLYLEGADQHRGWFQSSLLTGVAMDNAAPYKQCLTHGFTVDQHGRKMSKSLGNGIEP 629
Query: 637 EEVVERAGRDTFRFYMLWATNPWEN--------LKFSWKGVEQVRRMLNILWNVYVLAST 688
+++++ G D R ++ A+ + N LK + ++R L
Sbjct: 630 QDIIKTLGADILRLWI--ASTDYSNEMSLSQEILKRTTDAYRRIRNTARFLLG------- 680
Query: 689 YMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVED 748
+L FDP D+WI+ R L ++ + + + + NF D
Sbjct: 681 --NLHGFDPTLHLVPLSDMIALDRWIVHRAFELQQTIKAAYTRYDFAEIVQTILNFCSVD 738
Query: 749 LSRWYVRLIRKRLWVEGED-PDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPF 807
L Y+ + + RL+ ED P + +A ++ + +R +AP + A+E++ L P
Sbjct: 739 LGSLYLDVTKDRLYTMREDAPGRRSAQTAMYHLTAAFVRWIAPILSFTADELWSYL--PG 796
Query: 808 TNVESVHMLDW 818
+ ++V W
Sbjct: 797 DHADNVLFTTW 807
>pir||B81982 probable isoleucine--tRNA ligase (EC 6.1.1.5) NMA0622 [imported] -
Neisseria meningitidis (group A strain Z2491)
>gi|7379357|emb|CAB83912.1| (AL162753) putative
isoleucyl-tRNA synthetase [Neisseria meningitidis Z2491]
Length = 929
Score = 404 bits (1026), Expect = e-111
Identities = 284/861 (32%), Positives = 437/861 (49%), Gaps = 98/861 (11%)
Query: 21 KFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRTMQGYNV 80
K W E + Y+K++E+ K PK+ DGPPY +G IH+G A NKI+KD+IIR +T G++
Sbjct: 30 KSWYEQKRYQKLREIAKGRPKFILHDGPPYANGDIHIGHAVNKILKDIIIRSKTQAGFDA 89
Query: 81 WRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIMTEQFKML 140
PG+D HGLPIEV VE+ G K F + C+E+A + + F L
Sbjct: 90 PYVPGWDCHGLPIEVMVEKLHGKDMPK--------ARFRELCREYAAEQIARQKKDFIRL 141
Query: 141 GIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHEVRGEY 200
G+ DWDNPY+T+ + L ++ G L + + + +C C ++LAE EV EY
Sbjct: 142 GVLGDWDNPYLTMDFKTEADTVRMLGEIYKSGYLYRGAKPVQFCLDCGSSLAEAEV--EY 199
Query: 201 KLRKDPSIYVKFP---------------VEGKENEYLLIWTTTPWTLPANLAVSAHPDYD 245
K + P+I V +P +EGK + +IWTTTPWTLPA+ AVSA D
Sbjct: 200 KDKVSPAIDVGYPFKDTAALATAFGLAGIEGK--AFAVIWTTTPWTLPASQAVSAGADVV 257
Query: 246 YVKVKVEFNGREEYWILAKALVDKVLGEIGVKG--EVVEEFKGRELEGLRYVHILMD-EY 302
Y + G+ +LAK L + L G ++ E G +LE L H ++ +
Sbjct: 258 YQLIDTP-TGK---LVLAKDLAEDALKRYGFSDGIAILAETTGDKLENLHMNHPFLERDI 313
Query: 303 PRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQG 362
P ++ + VT + GTGLVHTAP HG ED+ V KYG+ +Y+P++ +G
Sbjct: 314 P--------------MLNGEHVTTDAGTGLVHTAPAHGLEDYAVCNKYGIELYNPVNAEG 359
Query: 363 KY--TEGKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWF 420
KY + G+ V EA+ I++ L E G L+ + +IEH Y HCWR KTPLI+RAT QWF
Sbjct: 360 KYIGETPRVAGMRVWEANSVILQWLEETGNLLASSKIEHSYAHCWRHKTPLIYRATGQWF 419
Query: 421 LKISK-------VKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPI 473
+ + K ++DK IK D+ ++P W + R + + DWV+SRQRYWG P+
Sbjct: 420 VGMDKAGADGKTLRDKAIKAVDD-TEFFPSWGRARLEAMIEGRPDWVVSRQRYWGTPMTF 478
Query: 474 W-QSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVD 532
+ E GE++ + EL+E VA + + IE S ++ E L ED
Sbjct: 479 FVHKETGELHPNSA--ELLE-KVAQRIEEKGIEAWFSLDK-----GELLSAEDC------ 524
Query: 533 AFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKW 592
+ ++ D +DVWFDSG ++ L K+ E WPAD +EG DQ W
Sbjct: 525 --------EHYDKLSDTMDVWFDSGSTHYSVL-----KQREELDWPADLYLEGSDQHRGW 571
Query: 593 FYSQQAASIV-AFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFY 651
F S + PY+++ HG+V+D+ G KMSKS+GN++ P+EV G D R
Sbjct: 572 FQSSMLTGCASSMGRAPYKQLLTHGFVVDQNGRKMSKSIGNVVAPQEVYNEFGADILR-- 629
Query: 652 MLWA--TNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFRE 709
LWA T+ L S + +++V + N L+ + +L +F+P + + E
Sbjct: 630 -LWAASTDYSGELAISKEILKRVTESYRRIRN--TLSFLFANLSDFNPIEDAVQQADMVE 686
Query: 710 EDKWILSRVNSLISEVENGIESFYLTK-ATRALYNFVVEDLSRWYVRLIRKRLW-VEGED 767
D++ L L V Y A + + +F EDL +Y+ +++ RL+ + +
Sbjct: 687 IDRYALVLARRLQERVAGDFYPRYAFHFAVKEMVSFCSEDLGAFYLDILKDRLYTTKADS 746
Query: 768 PDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHML-DWPKVDEKAI 826
+ +A L+ + L+ L+AP + EE + + + H ++P ++EKA
Sbjct: 747 RARRSAQTALYHITRSLVLLIAPILCFTGEEAWDIIGGGAEDSVLFHTWHEFPTINEKA- 805
Query: 827 DEELEREMEFIRRIVEAGSAA 847
+ EL ++ IR EA +AA
Sbjct: 806 EAELVKKWTAIREAREAVTAA 826
>sp|P18330|SYI_PSEFL ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|577085|emb|CAA56431.1| (X80132) isoleucine-tRNA
ligase [Pseudomonas fluorescens]
Length = 943
Score = 402 bits (1023), Expect = e-111
Identities = 276/857 (32%), Positives = 430/857 (49%), Gaps = 107/857 (12%)
Query: 16 EEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRTM 75
E ++ + W+ +Y K++E+ KD PK+ DGPPY +G IH+G A NKI+KDMI+R +T+
Sbjct: 25 EPQILQRWNSIGLYGKLREIGKDRPKFVLHDGPPYANGTIHIGHALNKILKDMILRSKTL 84
Query: 76 QGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIMTE 135
G++ PG+D HGLPIE KVE G + +G + + C+ +A ++
Sbjct: 85 SGFDAPYVPGWDCHGLPIEHKVEVTYG--------KNLGADKTRELCRAYATEQIEGQKS 136
Query: 136 QFKMLGIWMDWDNPY--MTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAE 193
+F LG+ +WDNPY M KNE E L + G + K + ++WC C +ALAE
Sbjct: 137 EFIRLGVLGEWDNPYKTMNFKNEAGEIR--ALAEIVKGGFVFKGLKPVNWCFDCGSALAE 194
Query: 194 HEVRGEYKLRKDPSIYVKFPV--EGKENE-----------YLLIWTTTPWTLPANLAVSA 240
EV EY+ +K +I V FP+ + K E ++IWTTTPWT+PAN A++
Sbjct: 195 AEV--EYEDKKSSTIDVAFPIADDAKLAEAFGLASLAKPAAIVIWTTTPWTIPANQALNV 252
Query: 241 HPDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMD 300
HP++ Y V V + +LA+ +V+ L ++G V+ G LE + + H
Sbjct: 253 HPEFTYALVDV----GDRLLVLAEEMVESCLARYELQGSVIATATGSALELINFRHPF-- 306
Query: 301 EYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGL---PVYSP 357
Y+ V LAD+V L GTG+VH +P +G +DF + +KYG+ + +P
Sbjct: 307 -----------YDRLSPVYLADYVELGSGTGIVHCSPAYGVDDFVICKKYGMVNDDIINP 355
Query: 358 LDDQGKYTEGK--WKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRA 415
+ G Y + G ++ +AD IIE LRE G L++ I+H Y HCWR KTPLI+RA
Sbjct: 356 VQSNGVYVPSLEFFGGQFIFKADQPIIEKLREVGALMQTAAIQHSYMHCWRHKTPLIYRA 415
Query: 416 TDQWFLKISK-------VKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWG 468
T QWF+ + K ++ + +K E + P W + R + + + DW ISRQR WG
Sbjct: 416 TAQWFIGMDKEPTSGDTLRVRSLKA-IEDTKFVPSWGQARLHSMIANRPDWCISRQRNWG 474
Query: 469 IPLPIW-QSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKV-IEEKLGPEDL 526
+P+P + E GE++ VEL +EV +R+E + E K+ E LG E
Sbjct: 475 VPIPFFLNKESGELH-----PRTVEL---MEVVAQRVE-QQGIEAWFKLDAAELLGDE-- 523
Query: 527 HRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASL--GYPRNKELFEKLWPADFIVE 584
P D ++ D +DVWFDSG W L +P E + AD +E
Sbjct: 524 -APLYD------------KISDTLDVWFDSGTTHWHVLRGSHPMGHETGPR---ADLYLE 567
Query: 585 GEDQVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAG 644
G DQ WF+S + PYR + HG+ +DE G KMSKSL N+I P+++ + G
Sbjct: 568 GSDQHRGWFHSSLLTGCAIDNHAPYRELLTHGFTVDETGRKMSKSLKNVIEPKKINDTLG 627
Query: 645 RDTFRFYMLWATNPWE---NLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLN 701
D R ++ E + + + + RR+ N +L F+P
Sbjct: 628 ADIMRLWVASTDYSGEIAVSDQILARSADAYRRIRN------TARFMLSNLTGFNPAS-- 679
Query: 702 PDELPFREE---DKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIR 758
D LP + D+W + R L E++ + ++NF V++L +Y+ +I+
Sbjct: 680 -DLLPAEDMLALDRWAVDRTLLLQRELQEHYGEYRFWNVYSKIHNFCVQELGGFYLDIIK 738
Query: 759 KRLWVEGEDPD-KLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLD 817
R + G + + +A L+ + + L+R +AP + A+E+++ L P ESV +
Sbjct: 739 DRQYTTGANSKARRSAQTALYHISEALVRWIAPILAFTADELWEYL--PGERNESVMLNT 796
Query: 818 WPK-VDEKAIDEELERE 833
W + + E D EL RE
Sbjct: 797 WYEGLTELPADFELGRE 813
>pir||G81036 isoleucyl-tRNA synthetase NMB1833 [imported] - Neisseria
meningitidis (group B strain MD58)
>gi|7227088|gb|AAF42168.1| (AE002533) isoleucyl-tRNA
synthetase [Neisseria meningitidis MC58]
Length = 929
Score = 397 bits (1010), Expect = e-109
Identities = 283/865 (32%), Positives = 440/865 (50%), Gaps = 106/865 (12%)
Query: 21 KFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRTMQGYNV 80
K W E + Y+K++E+ K PK+ DGPPY +G IH+G A NKI+KD+IIR +T G++
Sbjct: 30 KSWYEQKRYQKLREIAKGRPKFILHDGPPYANGDIHIGHAVNKILKDIIIRSKTQAGFDA 89
Query: 81 WRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIMTEQFKML 140
PG+D HGLPIEV VE+ G K F + C+E+A + + F L
Sbjct: 90 PYVPGWDCHGLPIEVMVEKLHGKDMPK--------ARFRELCREYAAEQIARQKKDFIRL 141
Query: 141 GIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHEVRGEY 200
G+ DWD+PY+T+ + L ++ G L + + + +C C ++LAE EV EY
Sbjct: 142 GVLGDWDHPYLTMDFKTEADTVRMLGEIYKSGYLYRGAKPVQFCLDCGSSLAEAEV--EY 199
Query: 201 KLRKDPSIYV------------KFPVEGKENE-YLLIWTTTPWTLPANLAVSAHPDYDYV 247
K + P+I V F + G E + + +IWTTTPWTLPA+ AVSA D Y
Sbjct: 200 KDKISPAIDVAYLFKDTAALAAAFGLAGFEGKAFAVIWTTTPWTLPASQAVSAGADVVYQ 259
Query: 248 KVKVEFNGREEYWILAKALVDKVLGEIGVKG--EVVEEFKGRELEGLRYVHILMD-EYPR 304
+ + +LAK L + L G ++ E G +LE L H ++ + P
Sbjct: 260 LIDTP----KGKLVLAKDLAEDALKRYGFSDGIAILAETTGDKLENLHMNHPFLERDIP- 314
Query: 305 QKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKY 364
++ + VT + GTGLVHTAP HG ED+ V KYG+ +Y+P++ +G+Y
Sbjct: 315 -------------MLNGEHVTTDAGTGLVHTAPAHGLEDYAVCNKYGIELYNPVNAEGRY 361
Query: 365 --TEGKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLK 422
+ G+ V EA+P I++ L E G L+ + +IEH Y HCWR KTPLI+RAT QWF+
Sbjct: 362 IGETPRVAGMRVWEANPVILQWLEETGNLLASSKIEHSYAHCWRHKTPLIYRATGQWFVG 421
Query: 423 ISK-------VKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIW- 474
+ K ++DK IK D+ ++P W + R + + DWV+SRQRYWG P+ +
Sbjct: 422 MDKAGADGKTLRDKAIKAVDD-TEFFPSWGRARLEAMIEGRPDWVVSRQRYWGTPMTFFV 480
Query: 475 QSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAF 534
E GE++ + EL+E VA+++ + IE S ++ E L ED
Sbjct: 481 HKETGELHPNSA--ELLE-KVALKIEEKGIEAWFSLDK-----SELLSAEDC-------- 524
Query: 535 IIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFY 594
++ ++ D +DVWFDSG S Y K+ E WPAD +EG DQ WF
Sbjct: 525 ------ENYDKLSDTMDVWFDSG-----STHYSVVKQREELEWPADLYLEGSDQHRGWFQ 573
Query: 595 SQQAASIV-AFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYML 653
S + PY+++ HG+V+D +G KMSKS+GN++ P+EV G D R L
Sbjct: 574 SSMLTGCASSMGRAPYKQLLTHGFVVDGEGKKMSKSIGNVVAPQEVYNEFGADILR---L 630
Query: 654 WA--TNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREED 711
WA T+ L S + +++V + N L+ + +L +F+P + + E D
Sbjct: 631 WAASTDYSGELAISKEILKRVTESYRRIRN--TLSFLFANLSDFNPIEDAVQQADMVEID 688
Query: 712 KWILSRVNSLISEVENGIESFYLTK-----ATRALYNFVVEDLSRWYVRLIRKRLWVEGE 766
++ + L +++ + Y + A + + +F EDL +Y+ +++ RL+
Sbjct: 689 RYAV----VLARQLQECLAGDYYPRYAFHFAVKDIVSFCSEDLGAFYLDILKDRLYTTKA 744
Query: 767 DPD-KLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDW---PKVD 822
D + +A L+ + L+ L+AP + EE + I +SV W P ++
Sbjct: 745 DSHARRSAQTALYHITRSLVLLIAPILCFTGEEAWD--IIGGGEEDSVLFHTWHEFPTIN 802
Query: 823 EKAIDEELEREMEFIRRIVEAGSAA 847
EK + EL ++ IR EA +AA
Sbjct: 803 EKT-EAELVKKWTAIREAREAVTAA 826
>pir||G75014 valyl-tRNA synthetase (vals) PAB1255 - Pyrococcus abyssi (strain
Orsay) >gi|5459071|emb|CAB50557.1| (AJ248288) valyl-tRNA
synthetase (valS) [Pyrococcus abyssi]
Length = 891
Score = 391 bits (994), Expect = e-107
Identities = 288/977 (29%), Positives = 467/977 (47%), Gaps = 134/977 (13%)
Query: 8 REYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKD 67
++YDP ++E K +K+W E +IY+ L ++ P Y PP+ SG +HLG + D
Sbjct: 4 KKYDPNEIEPKWQKYWLEEKIYKY--RLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWID 61
Query: 68 MIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFAL 127
+I R++ M+GYNV G+D HGLP E+KVE+ G+ TK + EE F+KKC E+
Sbjct: 62 IIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGI-TKDQPEE------FLKKCVEWTW 114
Query: 128 NNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRC 187
++ M +QF +G DWD Y T+ + Y + +L ++KGL+ +++ ++WCP+C
Sbjct: 115 QAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKC 174
Query: 188 ETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYV 247
T+LA+ EV Y + Y+K P+ Y+ I TT P +PA +AV HPD
Sbjct: 175 RTSLAKAEVG--YVEEEGYLYYIKLPLADGSG-YIPIATTRPELMPACVAVFVHPD---- 227
Query: 248 KVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKE 307
E Y K LV K VK + E R V IL DE
Sbjct: 228 --------DERY----KHLVGKK-----VKLPIYE----------REVPILADED----- 255
Query: 308 FKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTE- 366
V GTG V+ E+D ++Y LPV +++ G E
Sbjct: 256 ----------------VDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNEN 299
Query: 367 -GKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKY-PHCWR--CKTPLIFRATDQWFLK 422
G + G+ V+EA KI E L + G L K +I+H+ H R C P+ QWF++
Sbjct: 300 AGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIR 359
Query: 423 ISKVKDKIIKENDEKVTWYPDWVKIRFDNGVRDSG-DWVISRQRYWGIPLPIWQSEDGEI 481
+ D+I+K E + WYP+ + +R + DWVISRQR +G P P W ++G I
Sbjct: 360 VKDFTDEIVKVAKE-INWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGHI 418
Query: 482 YVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGK 541
+ EE L V +P V+ V G
Sbjct: 419 I-------------------------PAREEDLPVDPR------FDKPPVEK--CPVCGA 445
Query: 542 DMRRVKDVVDVWFDSGIAS-----W--ASLGYPRNKELFEKLWPADFIVEGEDQVTKWFY 594
++ V DV+D W DS I W A G K+ FE +P +G D + W +
Sbjct: 446 EIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAF 505
Query: 595 SQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLW 654
+ P++ + ++G V G KMSKS GN++ P+EV+ + G D R +
Sbjct: 506 YTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEVIPKYGADALRLWTAL 565
Query: 655 ATNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWI 714
A P E+ F W+ V+ R L +WN+Y A ++ +FD K EL D+WI
Sbjct: 566 AP-PGEDHPFKWETVDYNFRFLQKVWNIYRFAERHIK--DFDYEKYKDIEL--EPLDRWI 620
Query: 715 LSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAY 774
LSR++ +I +E + TR L F+ +++ Y+ +++ RL+ + E+ KL A
Sbjct: 621 LSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEMVKYRLYGDDEE-SKLKAK 679
Query: 775 YTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREM 834
L+++ ++ LLAPF P+I EEIY + + +SVH+L WP+ E IDE+ E+
Sbjct: 680 VALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGEKSVHLLSWPEYREDRIDEKAEKLG 739
Query: 835 EFIRRIVEAGSAARQRAKIKLRYPVRRIII---ETEDETVKKAVERLNRILRDQLNAKEV 891
E R++V + + L + + I E+ D+ ++ + + + +N +++
Sbjct: 740 ELARKVVSEMRKYKNSHGMPLNAKLEHVAIYALESYDD-----LKLIEKDIAGTMNIEKL 794
Query: 892 KVGR-----VERELTIKPNFAKLGPEFKGDAKIIAKWINEN----GRELYEKGELTVEID 942
++ + ER + +KPN+ ++GP + I + + N RE+ E G++ EID
Sbjct: 795 EIFKGEPQLEERIVEVKPNYKRIGPRYGKLVPRIVEHLKNNAESIAREIKENGKVEFEID 854
Query: 943 GKTFHLTREHIIVEEKL 959
G+ LT+E +++++++
Sbjct: 855 GEKVELTKEDVMIKKEV 871
>gi|11499806 valyl-tRNA synthetase (valS) [Archaeoglobus fulgidus]
>gi|3122909|sp|O28059|SYV_ARCFU VALYL-TRNA SYNTHETASE
(VALINE--TRNA LIGASE) (VALRS) >gi|7437638|pir||H69527
valyl-tRNA synthetase (valS) homolog - Archaeoglobus
fulgidus >gi|2648303|gb|AAB89032.1| (AE000952)
valyl-tRNA synthetase (valS) [Archaeoglobus fulgidus]
Length = 863
Score = 389 bits (988), Expect = e-106
Identities = 279/956 (29%), Positives = 447/956 (46%), Gaps = 138/956 (14%)
Query: 8 REYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKD 67
++YD ++EEK K W + Y + + P Y PPY +G+ H+G A N I D
Sbjct: 5 KDYDAHEVEEKWLKLWKDEMYYF---DWNSEKPHYIIDTPPPYPTGSFHIGHALNWCIID 61
Query: 68 MIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFAL 127
I R++ M GY V G+D HGLP EVKVE+ G+K + I + F + C EF
Sbjct: 62 FIARYKRMNGYEVMFPQGWDCHGLPTEVKVEEKYGIK-----KGDIPRDEFRRLCVEFTE 116
Query: 128 NNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRC 187
N+ M E + +G +DW Y+T+ EY + R + KGL+ +D + +CPRC
Sbjct: 117 ENIAKMRETARRMGYSIDWSKEYITMYPEYYSKTQLSFVRMYNKGLIYRDYHPVVFCPRC 176
Query: 188 ETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYV 247
ET +A E+ EY+ K Y+KF ++ ++I TT P +PA +A++ HPD +
Sbjct: 177 ETTIALAEI--EYRQGKTKLNYIKF------DDDVIIATTRPELIPACVAIAVHPDDE-- 226
Query: 248 KVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKE 307
R ++ I K V E+
Sbjct: 227 --------RNKHLIGKKVRVPTTPYEV--------------------------------- 245
Query: 308 FKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTE- 366
VI + V E GTG+V +D + +K+ L + + + G+ E
Sbjct: 246 ---------EVIADEEVDPEFGTGVVMICTFGDRQDVKWWKKHKLELRNIVGRDGRLNEK 296
Query: 367 -GKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISK 425
G++ G+ + EA I+E L+++G L+K EI+H CWRCKTP+ +QWF+K+ K
Sbjct: 297 AGRYAGMTIPEAREAILEDLKKEGKLLKQVEIDHNVGTCWRCKTPVEIIPAEQWFVKVEK 356
Query: 426 VKDKIIKENDEKVTWYPDWVKIRFDNGVRD-SGDWVISRQRYWGIPLPIWQSED-GEIYV 483
K I E +++ W P+ + R ++ V+ DWVISRQR + P+P W ++ GE+ V
Sbjct: 357 EK---ILEAAKRIKWVPEHMYSRLESWVQSMEWDWVISRQRIFATPIPAWYCKNCGEVVV 413
Query: 484 VGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDM 543
+ EE L V P + K +
Sbjct: 414 -------------------------AKEEWLPVDPTATQPPEP--------CPKCGSTEF 440
Query: 544 RRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVA 603
R DV+D W DS I G+P KE +P +G D + W + S+
Sbjct: 441 RGETDVLDTWMDSSITPLMICGWPSLKE-----YPTHLRPQGHDIIRTWAFYTILRSLAL 495
Query: 604 FDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNP--WEN 661
+P+ + ++G V E G KMSKSLGN+I PEEVVE+ G D R WA + ++
Sbjct: 496 EGQIPWYEIVINGMVFGEDGRKMSKSLGNVIVPEEVVEKYGVDALR---QWAASGVIGDD 552
Query: 662 LKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSL 721
+ F+WK V R W+ + T M + ++ P + D+ R+ D+WILS++N L
Sbjct: 553 IIFNWKDVIAASRFQQKFWS--ITRFTLMHISDYTPSE--EDKKLLRDADRWILSKLNRL 608
Query: 722 ISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVF 781
+ EV ++ + +A +A+ F + + Y+ +++ RL+ G + +K AA + L
Sbjct: 609 VGEVRKHMDEYRFDEAIKAIRTFTWYEYADNYLEIVKNRLY-SGSEEEKRAAKFVLSYAL 667
Query: 782 DVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREMEFIRRIV 841
DVL RLLAP TP++AEE + + SVH+ +P V+E+ +DE E+ E I+ IV
Sbjct: 668 DVLTRLLAPITPFMAEECWSHF-----REGSVHLQSYPVVEEEFLDERAEKAGEEIKEIV 722
Query: 842 EAGSAARQRAKIKLRYPVRRIII--ETEDETVKKAVERLNRILRDQLNAKEVKVGRVERE 899
A + + L P++++I+ + + V+ N + EV+ ER
Sbjct: 723 AAVRKFKHDKGLALNAPLKKLIVYSKLDGLDVRDIAGATNSEVEIVTEMPEVR----ERV 778
Query: 900 LTIKPNFAKLGPEFKGDAKIIAKWINENGRE----LYEKGELTVEIDGKTFHLTRE 951
+KP FA +GP F+ AK + K + +E L ++G + V +DG + + E
Sbjct: 779 KELKPKFAIIGPMFREKAKTLIKAVGSLSKEEKERLLKEGAIQVNLDGASVEVKAE 834
>sp|P46207|SYI_AQUPY ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|2147612|pir||I39658 isoleucine--tRNA ligase (EC
6.1.1.5) - Aquifex pyrophilus (fragment)
>gi|598059|gb|AAA87287.1| (L37096) isoleucyl-tRNA
synthetase [Aquifex pyrophilus]
Length = 529
Score = 383 bits (972), Expect = e-105
Identities = 232/561 (41%), Positives = 319/561 (56%), Gaps = 50/561 (8%)
Query: 87 DMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIMTEQFKMLGIWMDW 146
D HGLPIE VE+ L KK +E + F K C+E+A + I E+F LG+ DW
Sbjct: 1 DTHGLPIERAVEKELS--KKKIRKESLPKTEFRKLCREYANRYVNIQKEEFIRLGVLGDW 58
Query: 147 DNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHEVRGEYKLRKDP 206
+NPY+T+ EY + L + +EKGL + K+ ++WC +TA + EV EY ++DP
Sbjct: 59 ENPYLTMSPEYEATEIRELGKFFEKGLAYRSKKPVYWCIYDKTAEGQAEV--EYYEKEDP 116
Query: 207 SIYVKFP----VEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVKVKVEFNGREEYWIL 262
SIYVKFP +EGK+ Y +IWTTTPWTLPANL + D DY V+VE E WI+
Sbjct: 117 SIYVKFPLKKEIEGKK-AYAVIWTTTPWTLPANLGIMVKEDADYSLVEVE----GEVWIV 171
Query: 263 AKALVDKVLGEIG-VKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFKE---KYEWAHRV 318
AK L++ IG V+++ KGR+L GL Y H +D + E K W R+
Sbjct: 172 AKELLENFFKNIGKTYTRVLKDVKGRDLVGLEYEHPFVDRDELKGYLSEETLKNMW--RI 229
Query: 319 ILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTEGK---WKGIYVK 375
++FV+L+ GTGLVH APGHG+ED+ VG++Y L Y+PLDD G++ E +G+ V
Sbjct: 230 YPSEFVSLDTGTGLVHMAPGHGQEDYTVGKRYNLEPYAPLDDSGRFVEPAPEFIRGVRVF 289
Query: 376 EADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKIS-KVKDKIIK-- 432
+A+ II L+EKGYLV I H YPHCWRCK P+IFRAT QWF+ + + + K +
Sbjct: 290 DANKLIIALLKEKGYLVHEARIRHSYPHCWRCKNPVIFRATPQWFIGMDIEYEGKTLSGE 349
Query: 433 --ENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSED-GEIYVVGSWRE 489
E EKV W P++ K R + V + DW ISRQR+WG+P+ ++ E+ GE+ E
Sbjct: 350 SLEEIEKVKWIPEYGKNRIKSMVENRPDWCISRQRFWGVPITVFYCENCGEVIKDKEVFE 409
Query: 490 LVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDV 549
+ V G + +S EE L PE P K G R+ +D+
Sbjct: 410 RIASLVEKHPGGTDVWFEKSPEEIL--------PEGYKCP-------KCGGTSFRKEEDI 454
Query: 550 VDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVAFDTVPY 609
+DVWFDSG S AS+ P FEK AD +EG DQ WF + S+ ++ PY
Sbjct: 455 LDVWFDSG-CSHASVIRPLG---FEK---ADLYLEGSDQHRGWFQASLLESVGSYGEAPY 507
Query: 610 RRVAMHGYVLDEKGDKMSKSL 630
R V HG+++DE+G KMSKSL
Sbjct: 508 RSVLTHGFIVDEQGRKMSKSL 528
>sp|P41257|SYI_CAMJE ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|558850|gb|AAA91296.1| (U15295) isoleucyl-tRNA
synthetase [Campylobacter jejuni]
Length = 917
Score = 382 bits (971), Expect = e-104
Identities = 274/821 (33%), Positives = 420/821 (50%), Gaps = 100/821 (12%)
Query: 17 EKVEKFWSENEIYRKVKELRKDGPKYYFL-DGPPYVSGAIHLGTAWNKIIKDMIIRFRTM 75
++ +K++ +N Y K+KE RK+ K + L DGPPY +G IH+G A NKI+K+ II+
Sbjct: 26 QRFKKWFEQNYAYEKMKENRKNAKKSFTLHDGPPYANGHIHIGHALNKILKETIIKTHYF 85
Query: 76 QGYNVWRQPGYDMHGLPIEVKVEQALGLK----TKKEIEEKIGVENFIKKCKEFALNNLK 131
+G +V PG+D HGLPIE +VE LG K +KKEI E C++ A +
Sbjct: 86 KGESVRFTPGWDCHGLPIEQQVEVKLGEKKKSLSKKEIRE---------FCRQHASEFVD 136
Query: 132 IMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETAL 191
I E+FK LGI DWD PY+T+K E+ + + TL +KGLL + + + W ++AL
Sbjct: 137 IQREEFKNLGIIADWDKPYLTMKFEFEAAIYRTLCEIAKKGLLCERSKPVFWSWAAKSAL 196
Query: 192 AEHEVRGEYKLRKDPSIYVKFPVEGKENEYL-------LIWTTTPWTLPANLAVSAHPDY 244
AE EV EY+ ++D SI+V F ++ K + L +IWTTTPWTL AN A++ +P+
Sbjct: 197 AEAEV--EYQDKEDYSIFVAFDLDVKACKKLGVSKASAVIWTTTPWTLVANQAIALNPNE 254
Query: 245 DYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPR 304
+YV K E I A AL+ ++ + GE+ +E +E E L ++ L
Sbjct: 255 NYVITK-------EGLIFASALLKSMVEKGLTSGEIQKELNAKEFEKLEAINPLNGR--- 304
Query: 305 QKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKY 364
+I+ + V ++ G+GLVHTAPGHGE+D+ KYG+ V P+DD G Y
Sbjct: 305 ----------KSVLIMGEHVLMDGGSGLVHTAPGHGEDDYYACLKYGIEVLMPVDDSGCY 354
Query: 365 TE-------------GKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPL 411
E ++ G+++ +A+ KI+E L EK L+ + + H YP CWR P+
Sbjct: 355 DETLRAKRLLPSHLLEEFIGLHIFKANEKILELLGEK--LLHSSKFIHSYPFCWRTHKPV 412
Query: 412 IFRATDQWFLKISKVK------DKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQR 465
I+RAT QWF+ + + K + KE K T+YP R + V + DW ISRQR
Sbjct: 413 IYRATKQWFILMDEPKLQGKTLRECAKEQLLKTTFYPQSGVKRIGSMVENRPDWCISRQR 472
Query: 466 YWGIPLPIWQSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPED 525
WG P+ ++ ++ + + EL + AI E+ +E ++K L P +
Sbjct: 473 DWGTPIAFFRDKNTKEVIFDD--ELFDFVAAI---FEKHGADAWWEFEIK----DLIPTN 523
Query: 526 LHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEK-LWPADFIVE 584
K N +++ +V D++DVWFDSG A L N L++ A +E
Sbjct: 524 ----------SKYNAENLEKVYDILDVWFDSGSTFNAVL----NSGLYDAGEKRASMYLE 569
Query: 585 GEDQVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAG 644
G DQ WF S ++ PY + HG+ DEKG KMSKS GN+I PE V + G
Sbjct: 570 GSDQHRGWFQSSLLVGTAINESTPYESILTHGFTTDEKGQKMSKSKGNVIAPEYVAKTYG 629
Query: 645 RDTFRFYMLWATNPWENLKFSWKGVEQVRRMLNILWNV--YVLASTYMSLDNFDPRKLNP 702
+ R ++L ++ +LK S ++QV + N ++LA+T D + L
Sbjct: 630 VEILRLWIL-LSDYSSDLKISDNILKQVGEQYRKIRNTIRFLLANTN------DLKDLEV 682
Query: 703 DELPFREEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLW 762
E F DKWILSR + + + ++ K L NF+ DLS Y+ + + RL+
Sbjct: 683 KEFSF--IDKWILSRASKVFKASKEAFFAYEFAKGFSLLLNFLSADLSGIYLDISKDRLY 740
Query: 763 VEGEDPD-KLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQN 802
+ E+ + +A + + LL LLA Y +E ++
Sbjct: 741 CDSENAQRRKSAQVAMALIAKELLNLLASNLSYSVDEALEH 781
>pir||B81309 isoleucine--tRNA ligase (EC 6.1.1.5) Cj1061c [imported] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6968497|emb|CAB73317.1| (AL139077) isoleucyl-tRNA
synthetase [Campylobacter jejuni]
Length = 917
Score = 380 bits (965), Expect = e-104
Identities = 274/821 (33%), Positives = 418/821 (50%), Gaps = 100/821 (12%)
Query: 17 EKVEKFWSENEIYRKVKELRKDGPKYYFL-DGPPYVSGAIHLGTAWNKIIKDMIIRFRTM 75
++ +K++ +N Y K+KE RK+ K + L DGPPY +G IH+G A NKI+K+ II+
Sbjct: 26 QRFKKWFEQNYAYEKMKENRKNAKKSFTLHDGPPYANGHIHIGHALNKILKETIIKTHYF 85
Query: 76 QGYNVWRQPGYDMHGLPIEVKVEQALGLK----TKKEIEEKIGVENFIKKCKEFALNNLK 131
+G +V PG+D HGLPIE +VE LG K +KKEI E C++ A +
Sbjct: 86 KGESVRFTPGWDCHGLPIEQQVEVKLGEKKKSLSKKEIRE---------FCRQHASEFVD 136
Query: 132 IMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETAL 191
I E+FK LGI DWD PY+T+K E+ + + TL +KGLL + + + W ++AL
Sbjct: 137 IQREEFKDLGIIADWDKPYLTMKFEFEAAIYRTLCEIAKKGLLCERSKPVFWSWAAKSAL 196
Query: 192 AEHEVRGEYKLRKDPSIYVKFPVEGKENEYL-------LIWTTTPWTLPANLAVSAHPDY 244
AE EV EY+ ++D SI+V F ++ K E L +IWTTTPWTL AN A++ +P+
Sbjct: 197 AEAEV--EYQDKEDYSIFVAFDLDVKACEKLGVSKASAVIWTTTPWTLVANQAIALNPNE 254
Query: 245 DYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPR 304
+YV K E I A AL+ ++ + GE+ +E +E E L ++ L
Sbjct: 255 NYVITK-------EGLIFASALLKSMVEKGLTSGEIQKELNAKEFEKLEAINPLNGR--- 304
Query: 305 QKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKY 364
+I+ + V ++ G+GLVHTAPGHGE+D+ KYG+ V P+DD G Y
Sbjct: 305 ----------KSVLIMGEHVLMDGGSGLVHTAPGHGEDDYYACLKYGIEVLMPVDDSGCY 354
Query: 365 TE-------------GKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPL 411
E ++ G+++ +A+ KI+E L EK L+ + + H YP CWR P+
Sbjct: 355 DETLRAKGLLPSHLLEEFIGLHIFKANEKILELLGEK--LLHSSKFIHSYPFCWRTHKPV 412
Query: 412 IFRATDQWFLKISKVK------DKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQR 465
I+RAT QWF+ + + K + KE K T+YP R + V + DW ISRQR
Sbjct: 413 IYRATKQWFILMDEPKLQGKTLRECAKEQLLKTTFYPQSGVKRIGSMVENRPDWCISRQR 472
Query: 466 YWGIPLPIWQSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPED 525
WG P+ ++ ++ + + EL + AI E+ +E ++K L P +
Sbjct: 473 DWGTPIAFFRDKNTKEVIFDD--ELFDFVAAI---FEKHGADAWWEFEIK----DLIPTN 523
Query: 526 LHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEK-LWPADFIVE 584
K +++ +V D++DVWFDSG A L N L++ A +E
Sbjct: 524 ----------SKYKAENLEKVYDILDVWFDSGSTFNAVL----NSGLYDAGEKRASMYLE 569
Query: 585 GEDQVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAG 644
G DQ WF S ++ PY + HG+ DEKG KMSKS GN+I E V + G
Sbjct: 570 GSDQHRGWFQSSLLVGTAINESAPYESILTHGFTTDEKGQKMSKSKGNVIASEYVAKTYG 629
Query: 645 RDTFRFYMLWATNPWENLKFSWKGVEQVRRMLNILWNV--YVLASTYMSLDNFDPRKLNP 702
+ R ++L ++ +LK S ++QV + N ++LA+T D + L
Sbjct: 630 VEILRLWIL-LSDYSSDLKISDNILKQVGEQYRKIRNTIRFLLANTN------DLKDLEV 682
Query: 703 DELPFREEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLW 762
E F DKWILSR + + ++ K L NF+ DLS Y+ + + RL+
Sbjct: 683 KEFSF--IDKWILSRATKVFKASKEAFFAYEFAKGFSLLLNFLSADLSGIYLDISKDRLY 740
Query: 763 VEGEDPD-KLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQN 802
+ E+ + +A + + LL LLAP Y +E ++
Sbjct: 741 CDSENAQRRKSAQVAMALMAKELLNLLAPNLSYSVDEALEH 781
>sp|Q9ZJJ1|SYI_HELPJ ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|7437555|pir||F71823 isoleucine--tRNA ligase (EC
6.1.1.5) - Helicobacter pylori (strain J99)
>gi|4155922|gb|AAD06890.1| (AE001554) ISOLEUCYL-TRNA
SYNTHETASE [Helicobacter pylori J99]
Length = 920
Score = 379 bits (963), Expect = e-104
Identities = 275/858 (32%), Positives = 426/858 (49%), Gaps = 99/858 (11%)
Query: 16 EEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRTM 75
E K W E + +++++ + + + DGPPY +G +HLG A NKI+KD++I+
Sbjct: 25 EPKTYAKWQEQQAFKRMQNRKDNHGDFTLHDGPPYANGHLHLGHALNKILKDIVIKREYF 84
Query: 76 QGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVEN---FIKKCKEFALNNLKI 132
+G ++ PG+D HGLPIE ++ + L +EK +EN F +KC++ A L+I
Sbjct: 85 KGKKIYYTPGWDCHGLPIEQQILEQLE-------KEKTSLENPTLFREKCRDHAKKFLEI 137
Query: 133 MTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALA 192
+F LG+ D+++PY T+ ++ S + L +KGLL++ + ++W CE+ALA
Sbjct: 138 QKNEFLQLGVLGDFEDPYKTMDFKFEASIYRALVGVAKKGLLKERHKPIYWSYACESALA 197
Query: 193 EHEVRGEYKLRKDPSIYVKFPV--EGKE-----NEYLLIWTTTPWTLPANLAVSAHPDYD 245
E EV EYK++K PSI+V F + EG E L+IWTTTPWTL AN+A++ D
Sbjct: 198 EAEV--EYKMKKSPSIFVAFDLKKEGLEKLKVKKASLVIWTTTPWTLYANVAIALKKDAV 255
Query: 246 YVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQ 305
Y ++ +++AKAL +K+ V + EF +LE L + L Q
Sbjct: 256 YALT-------QKGYLVAKALHEKLAALGVVDNAITHEFNSNDLEYLVATNPL-----NQ 303
Query: 306 KEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYT 365
++ V+L D V+LE+GTG VHTAPGHGEED+ +G KY L V +D++G Y
Sbjct: 304 RD--------SLVVLGDHVSLEDGTGAVHTAPGHGEEDYYLGLKYHLEVLMSVDEKGCYD 355
Query: 366 EG---------KWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRAT 416
EG + G ++ +A +IIE L + L+ EIEH YPHCWR P+I+RAT
Sbjct: 356 EGIIHNQLLDKSYLGEHIFKAQKRIIEQLGDS--LLLEREIEHSYPHCWRTHKPVIYRAT 413
Query: 417 DQWFLKI----------SKVKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRY 466
QWF+ + K ++ + EKV + P K R + + DW +SRQR
Sbjct: 414 TQWFILMDEPFIQNDGSQKTLREVALDAIEKVEFVPSSGKNRLKTMIENRPDWCLSRQRK 473
Query: 467 WGIPLPIWQSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDL 526
WG+PL + + S E++E + +EEK + + +DL
Sbjct: 474 WGVPLAFFIDKRTNKPCFES--EVLE------------HVANLFEEKGCDVWWEYNIKDL 519
Query: 527 HRP-YVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASL-GYPRNKELFEKLWPADFIVE 584
P Y D N K +V ++DVWFDSG A L Y K P+D ++E
Sbjct: 520 LPPSYQD------NAKHYEKVMHILDVWFDSGSTFKAVLEDYHGEKGQS----PSDVVLE 569
Query: 585 GEDQVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAG 644
G DQ WF S V + P+++V HG+++DEKG+KMSKS GN++ + ++++ G
Sbjct: 570 GSDQHRGWFQSSLLIGCVLNNQAPFKKVITHGFIVDEKGEKMSKSKGNVVSLDNLLKKHG 629
Query: 645 RDTFRFYMLWATNPWEN-LKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPD 703
D R ++ A N ++N L+ S Q + N + L NF L
Sbjct: 630 SDVVRLWV--AFNDYQNDLRVSQTFFIQTEQHYKKFRN-----TLKFLLANFSDMDLKNL 682
Query: 704 ELP--FREEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRL 761
E P F D +IL + ++ + V + E L K L FV +LS Y+ + L
Sbjct: 683 ERPHDFSPLDHFILEALETISAGVNSAFEEHDLVKGLNILMAFVTNELSGIYLDACKDSL 742
Query: 762 WVEGEDPDK-LAAYYTLWKVFDVLLRLLAPFTPYIAEEI--YQNLIRPFTNVESVHMLDW 818
+ + ++ +K A L V L LAP + EE+ + ++R F + V L
Sbjct: 743 YCDSKNNEKRQAIQMVLLAVASQLCYFLAPILTHTIEEVLEHSQVLRAFLQAKDVFDLKG 802
Query: 819 PKVDEKAIDEELEREMEF 836
V EK +E ++ F
Sbjct: 803 ISVLEKLHLKEFKKPENF 820
>dbj|BAA01304.1| (D10483) isoleucyl-tRNA ligase [Escherichia coli]
Length = 936
Score = 378 bits (961), Expect = e-103
Identities = 260/815 (31%), Positives = 411/815 (49%), Gaps = 86/815 (10%)
Query: 11 DPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMII 70
D K E + W+++++Y ++ +K + DGPPY +G+IH+G + NKI+KD+I+
Sbjct: 20 DLAKREPGMLARWTDDDLYGIIRAAKKGKKTFILHDGPPYANGSIHIGHSVNKILKDIIV 79
Query: 71 RFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNL 130
+ + + GY+ PG+D HGLPIE+KVEQ G + EK F KC+E+A +
Sbjct: 80 KSKGLSGYDSPYVPGWDCHGLPIELKVEQEYG-----KPGEKFTAAEFRAKCREYAATQV 134
Query: 131 KIMTEQFKMLGIWMDWDNPYMTIK-NEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCET 189
+ F LG+ DW +PY+T+ + + L + G L K + +HWC C +
Sbjct: 135 DGQRKDFIRLGVLGDWSHPYLTMGLQNWKANIIRALGKIIGNGHLHKGAKPVHWCVDCRS 194
Query: 190 ALAEHEVRGEYKLRKDPSIY----------VKFPVEGKENEY-LLIWTTTPWTLPANLAV 238
ALA+ ++ KL + ++ KF V L+IWTTTPWTLPAN A+
Sbjct: 195 ALAKRKLSITTKLLRPSTLLSRAVDQDALKAKFAVSNVNGPISLVIWTTTPWTLPANRAI 254
Query: 239 SAHPDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHIL 298
S PD+DY V+++ + ILAK LV+ V+ IGV K + H
Sbjct: 255 SIAPDFDYALVQID----GQAVILAKDLVESVMQRIGVTDS--RHGKRCGAGAAAFTHPF 308
Query: 299 MD-EYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSP 357
M + P IL D VTL+ GTG VHTAPGHG +D+ +GQKYGL +P
Sbjct: 309 MGFDVP--------------AILGDHVTLDAGTGAVHTAPGHGPDDYVIGQKYGLETANP 354
Query: 358 LDDQGKYTEGKWK---GIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFR 414
+ G Y G + G+ V +A+ + L+EKG L+ +++H YP CWR KTP+IFR
Sbjct: 355 VGPDGTYLPGTYPTLDGVNVFKANDIVAALLQEKGALLHVEKMQHSYPCCWRHKTPIIFR 414
Query: 415 ATDQWFLKISK--VKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLP 472
AT QWF+ + + ++ + +KE + V W PDW + R ++ V + DW ISRQR WG+P+
Sbjct: 415 ATPQWFVSMDQKGLRAQSLKEI-KGVQWIPDWGQARIESMVANRPDWCISRQRTWGVPMS 473
Query: 473 IWQSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVD 532
++ +D E + + E+A +EV+G I+ + K E LG E D
Sbjct: 474 LFVHKDTEELHPRTLELMEEVAKRVEVDG--IQAWWDLDAK-----EILGDE------AD 520
Query: 533 AFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKW 592
++ +V D +DVWFDSG ++ +S+ R + AD +EG DQ W
Sbjct: 521 QYV---------KVPDTLDVWFDSG-STHSSVVDVRPEFAGHA---ADMYLEGSDQHRGW 567
Query: 593 FYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYM 652
F S S PYR+V HG+ +D +G KMSKS+GN + P++V+ + G D R ++
Sbjct: 568 FMSSLMISTAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQDVMNKLGADILRLWV 627
Query: 653 LWATNPWE---NLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFRE 709
E + + + + RR+ N ++LA +L+ FDP K D + RE
Sbjct: 628 ASTDYTGEMAVSDEILKRAADTYRRIRNTA--RFLLA----NLNGFDPAK---DMVKRRE 678
Query: 710 E---DKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKR-LWVEG 765
D+W + + TK + L F ++ +Y+ +I+ R + +G
Sbjct: 679 MVVLDRWAVVVRKRHRKTSSRRTKHTISTKWYKRLMRFCSVEMGSFYLDIIKDRQYYAKG 738
Query: 766 EDPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIY 800
+ + L+ + + L+R +AP + A+E++
Sbjct: 739 HSVARRSCQTALYHIAEALVRWMAPILSFTADEVW 773
>sp|P75258|SYI_MYCPN ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|2146323|pir||S73648 isoleucine--tRNA ligase (EC
6.1.1.5) ileS - Mycoplasma pneumoniae (strain ATCC
29342) >gi|1673995|gb|AAB95970.1| (AE000029)
isoleucine-tRNA ligase [Mycoplasma pneumoniae]
Length = 861
Score = 372 bits (945), Expect = e-101
Identities = 257/861 (29%), Positives = 431/861 (49%), Gaps = 96/861 (11%)
Query: 16 EEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRTM 75
E++ + FW IY+K+ KD P+ DGPPY +G IH+G A NKI+KD ++R +
Sbjct: 24 EQQFQAFWQSKRIYQKLHRQNKDKPQKILHDGPPYANGNIHVGHALNKILKDFVLRSWNL 83
Query: 76 QGYNVWRQPGYDMHGLPIEVKVEQ-------ALGLKTKKEIEEKIGVENFIKKCKEFALN 128
QG+ PG+D HGLPIE V + +L L K+++ CK+FAL+
Sbjct: 84 QGFGTVFIPGWDCHGLPIEHAVSKKDPQHYASLSLSEKRDL------------CKQFALS 131
Query: 129 NLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCE 188
+ I QF+ LG+ D+ Y TI + ++ +A +K L+ + + +W P
Sbjct: 132 QIAIQKAQFQRLGLLNDFSKYYKTIDESFQQNELDLFLQAVKKDLIFQALKPTYWSPVSR 191
Query: 189 TALAEHEVRGEYKLRKDPSIYVKFPVEG----KENEYLLIWTTTPWTLPANLAVSAHPDY 244
T+LAE E+ EYK K +Y+ F V LL+WTTTPWTLP N A++ HP +
Sbjct: 192 TSLAEAEI--EYKEVKTIGLYLTFTVVQSAVLNSGTKLLVWTTTPWTLPTNQAIAVHPQF 249
Query: 245 DYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEV-VEEFKGRELEGLRYVHILMDEYP 303
+Y+ F E +++ +L + + + G + V+ G +L+ Y H L
Sbjct: 250 EYLL----FTYNNEQYVVLASLFESLKTKFGWTDAIQVQTISGSQLQNTTYKHCL----- 300
Query: 304 RQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGL-PVYSPLDDQG 362
Y+ + V+L + V EGTGLVHT+P +G +DF + ++ L LD++G
Sbjct: 301 --------YDKVNPVLLGNHVLCNEGTGLVHTSPAYGLDDFYLCKQNKLNEALVSLDEKG 352
Query: 363 KY----TEGKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQ 418
+ + G++ +A+ IIE L++ V + H+ PH WR KTP+I+RA+ Q
Sbjct: 353 VFNDTLNDPVLTGLFYLKANDVIIERLKQHHNFVFSESFLHREPHDWRSKTPVIYRASKQ 412
Query: 419 WFLKISKVKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSED 478
F+K ++ K +K ++V + + K R + +W ISRQR WG+P+P+ +++
Sbjct: 413 LFIKTKSIQSK-LKRQIKRVKFVNNKNKERLQEMLLQRAEWCISRQRVWGLPIPLIYADN 471
Query: 479 GEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKV 538
+ V + + ++ + +S+ E K I L P+ +
Sbjct: 472 QPLLDVTTIKYTIQQLKKYGI--------DSWFE--KDINFFLNPKKIQ----------- 510
Query: 539 NGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQA 598
G + ++ D ++VWFDSG + N +PAD +EG DQ WF S +
Sbjct: 511 PGVEYKKETDTLEVWFDSGSTYNVLISNKLN-------FPADLYLEGSDQYRGWFNSSAS 563
Query: 599 ASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATN- 657
I+ D +P++ + HG+ LDE G+KMSKSLGN++ P ++ ++ G D R LW TN
Sbjct: 564 CGIIQTDQLPFKSLISHGFTLDEHGNKMSKSLGNVVDPLKLCDQYGADILR---LWVTNV 620
Query: 658 PWE-----NLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDK 712
W+ + VEQ RR+ N L ++L + ++ NF K + F EDK
Sbjct: 621 DWQVDNRIGDNIIKQIVEQYRRIRNSLLR-FILGN--LNHFNFGEMK----DYRFALEDK 673
Query: 713 WILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGE-DPDKL 771
++ + N+L+ E+ ++ + +A+ FV+ LS WY +I+ L+ + + +P+++
Sbjct: 674 IVIHKTNALVQELHQWLKQYNFLNCLKAINKFVLW-LSGWYFEIIKDTLYCDAKTNPNRV 732
Query: 772 AAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELE 831
A L +F L+ L F P+ AE+ +QN + P V SV++ P + + A + L+
Sbjct: 733 AKQAVLNYIFTQLIGFLNIFIPHTAEDAWQNYLLPKKPV-SVNLFAGPAMFKVANVKGLD 791
Query: 832 REMEFIRRIVEAGSAARQRAK 852
R E I + AA ++A+
Sbjct: 792 RLHESFSAIKDRAYAAIEQAR 812
>gb|AAD56932.1|AF180145_24 (AF180145) isoleucyl-tRNA synthetase [Zymomonas mobilis]
Length = 941
Score = 370 bits (940), Expect = e-101
Identities = 265/846 (31%), Positives = 427/846 (50%), Gaps = 90/846 (10%)
Query: 14 KLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFR 73
K E ++ W + ++Y++++E RK ++ DGPPY +G IH+G A NKI+KD+I+R +
Sbjct: 34 KKEPEILARWQKEDLYQQLREQRKGAERFILHDGPPYANGDIHIGHALNKILKDIIMRTK 93
Query: 74 TMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIM 133
+ G +V PG+D HGLPIE KVE+ K K +++ + F +KC+++A++ +
Sbjct: 94 PLLGKDVPYIPGWDCHGLPIEWKVEEQFR-KKKLNVDKDVNAVEFRQKCRKYAVHWVDTQ 152
Query: 134 TEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAE 193
++FK LG+ +WDNPY+T+ E L R E G + + + + W +TALAE
Sbjct: 153 RQEFKRLGVLGEWDNPYLTMNFEAEAIISGELMRFSETGQIYRGAKPVLWSVVEKTALAE 212
Query: 194 HEVRGEYKLRKDPSIYVKFPVEGKE-----NEYLLIWTTTPWTLPANLAVSAHPDYDYVK 248
EV +Y +I + F + + Y +IWTTTPWT+PAN A++ PD DYV
Sbjct: 213 AEV--DYADVDSTTIDLAFKITDSKIPELVGGYAVIWTTTPWTIPANRALAYGPDIDYVL 270
Query: 249 VKVEFNGREEYWILAKALVDKVLGEIGVKGE--VVEEFKGRELEGLRYVHILMDEYPRQK 306
V + NG+ +++ A+AL++ L IG +G+ V+ KG EL+G H + ++
Sbjct: 271 V--DLNGK--HYLFAEALLEDSLKRIGHEGDAPVLWRGKGAELDGSIAQHPMFEKGGFFA 326
Query: 307 EFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTE 366
E + +H VT E GTG+VH AP +GE+DF + + + + ++D G+Y +
Sbjct: 327 EPRPFLGGSH-------VTTEAGTGIVHMAPDYGEDDFLLCKAHNIDPVFAVEDDGRYRK 379
Query: 367 G-KWKG-------IYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQ 418
W G + AD I LRE G L+ + H YPH WR K LI+R T Q
Sbjct: 380 DWLWMGGEGLVISPKINAADGPICSDLREVGALLATSVLHHSYPHSWRSKAKLIYRCTPQ 439
Query: 419 WFLKISK-----------VKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYW 467
WF+ + + +++ +K DE V+W+P K R V DWVISRQR W
Sbjct: 440 WFIALDRPVEKGAIAGKTLRETALKAIDE-VSWFPAKGKNRIQTMVEGRPDWVISRQRAW 498
Query: 468 GIPLPIWQSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLH 527
G+P+ ++ + + +G+ + PE ++ K G +
Sbjct: 499 GVPITLYVNRE---------------------SGDYLRDPE-VNARILAAFRKEGADAWF 536
Query: 528 RPYVDAFI-IKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGE 586
+ F+ K +D V D++DVWFDSG ++ A + R E A +EG
Sbjct: 537 KANHQLFLGDKYRLEDYEPVNDILDVWFDSG-STHAFVVEARYGEGTR----AQLYLEGS 591
Query: 587 DQVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRD 646
DQ WF S S + PY V HG+ LD G KMSKS+GN+I P +V+ +G D
Sbjct: 592 DQHRGWFQSSLLESCGSRGHAPYEAVLTHGFTLDGTGRKMSKSVGNVIDPLKVINESGAD 651
Query: 647 TFRFYMLWATNPWENLKFS---WKGVEQVRRMLNILWNVYVLASTYMSLDNF-DPRKLNP 702
R ++ +T+ E+++ S G R L + Y+L +L+ F + K++
Sbjct: 652 ILRMWVA-STDYNEDVRISKEVLSGTSDGYRKLRNSFR-YLLG----ALEGFSEEEKVDL 705
Query: 703 DELPFREEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLW 762
+LP E +K+IL + L + + F + R L +FV DLS ++ + + RL+
Sbjct: 706 ADLP--ELEKYILHLLAELDQALHESVNGFAFNRYLRLLSDFVNNDLSAFFFDIRKDRLY 763
Query: 763 VE-----GEDPDKLAAYYTLWKV-FDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHML 816
+ + ++ AY T+ + F L+R AP + AEE++ + F + SVH+
Sbjct: 764 CDVGEAAPQGTEERRAYRTVLDILFHALVRYAAPILCFTAEEVW---LHRFPDAGSVHLS 820
Query: 817 DWPKVD 822
WP+VD
Sbjct: 821 VWPEVD 826
>pir||D72206 valine--tRNA ligase (EC 6.1.1.9) - Thermotoga maritima (strain
MSB8) >gi|4982399|gb|AAD36880.1|AE001819_3 (AE001819)
valyl-tRNA synthetase [Thermotoga maritima]
Length = 865
Score = 369 bits (937), Expect = e-100
Identities = 250/900 (27%), Positives = 423/900 (46%), Gaps = 127/900 (14%)
Query: 10 YDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMI 69
Y+P ++E K ++W E + + G K+ + PP ++G IH+G A N ++D++
Sbjct: 8 YNPAEIETKWYRYWEEKGYFTP----KGVGEKFSIVIPPPNITGRIHMGHALNITLQDIV 63
Query: 70 IRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNN 129
+R++ M+GY+V PG D G+ + VE+ L L+T+ + E+IG E F++ E+A
Sbjct: 64 VRYKRMKGYDVLWVPGEDHAGIATQNAVEKFL-LQTQGKTREEIGREKFLEITWEWANKY 122
Query: 130 LKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCET 189
+ + EQ K LG +DW T+ + + KGL+ + K +++WCPRC+T
Sbjct: 123 RREIREQIKALGASVDWTRERFTLDEGLSRAVRKVFVELYRKGLIYRGKYIVNWCPRCKT 182
Query: 190 ALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVKV 249
L++ EV E+K K YVK+PV+ + EY+++ TT P T+ + AV+ HP+ + K
Sbjct: 183 VLSDEEV--EHKEHKSKLYYVKYPVKDSD-EYIVVATTRPETMLGDTAVAVHPEDERYKN 239
Query: 250 KVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFK 309
V K L+ ++G R + ++ D+Y
Sbjct: 240 FV-----------GKTLILPLVG--------------------REIPVVADKY------- 261
Query: 310 EKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTE--G 367
V + GTG V P H D+ + Q++ LP+ DD + E G
Sbjct: 262 --------------VDPKFGTGAVKVTPAHDPNDYLIAQRHNLPMIEIFDDNARINENGG 307
Query: 368 KWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVK 427
K+KG+ EA KI++ L E+G+LVK + H HC+RC T + + +DQWF+ +
Sbjct: 308 KYKGLDRYEAREKIVKDLEEQGFLVKIEDYTHSVGHCYRCDTVIEPKLSDQWFVSTKPLA 367
Query: 428 DKIIK--ENDEKVTWYPD-WVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVV 484
+ I+ EN E + ++P+ W K+ + N + + DW ISRQ +WG +P+W +D
Sbjct: 368 KRAIEAVENGE-IRFFPERWTKV-YLNWMYEIRDWCISRQLWWGHRIPVWYCQD------ 419
Query: 485 GSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMR 544
+ V+ E +E E K +++
Sbjct: 420 ---------CGHLNVSEEDVEKCE----------------------------KCGSTNLK 442
Query: 545 RVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVAF 604
+ +DV+D WF S + +++LG+P E ++ +P D +V G D + W
Sbjct: 443 QDEDVLDTWFSSALWPFSTLGWPEETEDLKRYYPTDLLVTGFDIIFFWVARMIMMGYEFM 502
Query: 605 DTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENLKF 664
+ P+ V +H V D+ G KMSKSLGN I P EV++ G D RF + ++K
Sbjct: 503 NDKPFSHVYIHQLVRDKYGRKMSKSLGNGIDPLEVIDEYGADPMRFTLAILAAQGRDIKL 562
Query: 665 SWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISE 724
+ + ++ N +WN +T L N + K P E + DKWIL+R+N + E
Sbjct: 563 DPRYFDAYKKFANKIWN-----ATRFVLMNLEDYKEVPLE-NLKTVDKWILTRLNKTVEE 616
Query: 725 VENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFDVL 784
V N +E++ A R +YNF +D WY+ + RL E ++ L KV D
Sbjct: 617 VTNALENYDFNIAARTIYNFFWDDFCDWYIEASKPRLKTE----ERNLVQTVLVKVLDAS 672
Query: 785 LRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREMEFIRRIVEAG 844
LRLL PF P++ EE++Q L P ES+ + WP+++ + IDE E+E + +V
Sbjct: 673 LRLLHPFMPFLTEELWQKL--PVAG-ESITIAKWPEIERELIDETAEKEFTRLMNMVRGV 729
Query: 845 SAARQRAKI----KLRYPVRRIIIETEDETVKKAVERLNRILRDQLNAKEVKVGRVEREL 900
R + +++ ++ + E+E + K + + + + VE E+
Sbjct: 730 RNVRAEMNLPQSQRVKVYIKGYEVTEEEELLLKTLGNIEEVSFVNEKPPKTATAYVEEEI 789
>sp|P56456|SYI_HELPY ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|7437556|pir||F64697 isoleucine--tRNA ligase (EC
6.1.1.5) - Helicobacter pylori (strain 26695)
>gi|2314596|gb|AAD08464.1| (AE000642) isoleucyl-tRNA
synthetase (ileS) [Helicobacter pylori 26695]
Length = 920
Score = 368 bits (935), Expect = e-100
Identities = 269/867 (31%), Positives = 422/867 (48%), Gaps = 117/867 (13%)
Query: 16 EEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRTM 75
E K W E + +++++ + + + DGPPY +G +HLG A NKI+KD++++
Sbjct: 25 EPKTYAKWQEQQAFKRMQARKDNHGDFTLHDGPPYANGHLHLGHALNKILKDIVVKREYF 84
Query: 76 QGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVEN---FIKKCKEFALNNLKI 132
+G ++ PG+D HGLPIE ++ + L +EK +EN F +KC++ A L+I
Sbjct: 85 KGKKIYYTPGWDCHGLPIEQQILERLE-------KEKTSLENPTLFREKCRDHAKKFLEI 137
Query: 133 MTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALA 192
+F LG+ D+++PY T+ ++ S + L +KGLL++ + ++W CE+ALA
Sbjct: 138 QKNEFLQLGVLGDFEDPYKTMDFKFEASIYRALVEVAKKGLLKERHKPIYWSYACESALA 197
Query: 193 EHEVRGEYKLRKDPSIYVKFPVEGKENE-------YLLIWTTTPWTLPANLAVSAHPDYD 245
E EV EYK++K PSI+V F ++ + E L+IWTTTPWTL AN+A++ D
Sbjct: 198 EAEV--EYKMKKSPSIFVAFGLKKESLEKLKVKKASLVIWTTTPWTLYANVAIALKKDAV 255
Query: 246 YVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQ 305
Y ++ +++AKAL +K+ V E+ EF +LE L + L Q
Sbjct: 256 YALT-------QKGYLVAKALHEKLAALGVVDNEITHEFNSNDLEYLVATNPL-----NQ 303
Query: 306 KEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYT 365
++ V L + V LE+GTG VHTAPGHGEED+ +G +Y L V +D++G Y
Sbjct: 304 RD--------SLVALGEHVGLEDGTGAVHTAPGHGEEDYYLGLRYNLEVLMSVDEKGCYD 355
Query: 366 EG---------KWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRAT 416
EG + G +V +A +IIE L + L+ EIEH YPHCWR P+I+RAT
Sbjct: 356 EGIIHNQLLDESYLGEHVFKAQKRIIEQLGDS--LLLEQEIEHSYPHCWRTHKPVIYRAT 413
Query: 417 DQWFLKI----------SKVKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRY 466
QWF+ + K ++ + EKV + P K R + + DW +SRQR
Sbjct: 414 TQWFILMDEPFIQNDGSQKTLREVALDAIEKVEFVPSSGKNRLKTMIENRPDWCLSRQRK 473
Query: 467 WGIPL----------PIWQSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKV 516
WG+PL P ++SE + V + E V E + + + LP SY+E
Sbjct: 474 WGVPLAFFIDKRTNKPCFESE--VLEHVANLFEKKGCDVWWEYSVKDL-LPPSYQE---- 526
Query: 517 IEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASL-GYPRNKELFEK 575
+ K ++ ++DVWFDSG A L Y K
Sbjct: 527 ----------------------DAKHYEKIMHILDVWFDSGSTFKAVLEDYHGEKGQS-- 562
Query: 576 LWPADFIVEGEDQVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIR 635
P+D I+EG DQ WF S V + P+++V HG+++DEKG+KMSKS GN++
Sbjct: 563 --PSDVILEGSDQHRGWFQSSLLIGCVLNNQAPFKKVITHGFIVDEKGEKMSKSKGNVVS 620
Query: 636 PEEVVERAGRDTFRFYMLWATNPWEN-LKFSWKGVEQVRRMLNILWNVYVLASTYMSLDN 694
+++++ G D R ++ A N ++N L+ S Q + N + L N
Sbjct: 621 LDKLLKTHGSDVVRLWV--AFNDYQNDLRVSQTFFTQTEQHYKKFRN-----TLKFLLAN 673
Query: 695 FDPRKLNPDELP--FREEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRW 752
F L E P F D ++L + ++ + V + E K L FV +LS
Sbjct: 674 FSDMDLKNLERPHNFSPLDHFMLETLETISAGVNSAFEEHDFVKGLNILMAFVTNELSGI 733
Query: 753 YVRLIRKRLWVEGEDPDK-LAAYYTLWKVFDVLLRLLAPFTPYIAEEI--YQNLIRPFTN 809
Y+ + L+ + ++ +K A L L LAP + EE+ + +R F
Sbjct: 734 YLDACKDSLYCDSKNNEKRQAIQMVLLATASKLCYFLAPILTHTIEEVLEHSQALRIFLQ 793
Query: 810 VESVHMLDWPKVDEKAIDEELEREMEF 836
+ V L V EK +E ++ F
Sbjct: 794 AKDVFDLKDISVSEKLHLKEFKKPENF 820
>gb|AAF49539.1| (AE003528) CG5414 gene product [Drosophila melanogaster]
Length = 890
Score = 364 bits (924), Expect = 3e-99
Identities = 253/793 (31%), Positives = 395/793 (48%), Gaps = 80/793 (10%)
Query: 29 YRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRTMQGYNVWRQPGYDM 88
Y++ + K P + DGPPY +G +H+G A NKI+KD+ +R R G V PG+D
Sbjct: 46 YQEQRLAEKGKPTFVLHDGPPYANGQLHMGHAVNKILKDITLRQRVAHGQRVNYIPGWDC 105
Query: 89 HGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIMTEQFKMLGIWMDW-- 146
HGLPIE+K ++ +EI +K + FA +K E+F GI +W
Sbjct: 106 HGLPIELKATSTAPGQSAQEIRQK---------SRAFAWEAIKSQKEEFSSWGILANWQK 156
Query: 147 DNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHEVRGEYKLRK-D 205
DN YMT + E+I + +EKGL+ +D + ++W P TALAE E+ EY
Sbjct: 157 DNIYMTFQPEFIVNQLEMFYNLYEKGLVYRDLKPVYWSPSSRTALAEAEL--EYDANHIS 214
Query: 206 PSIYVKFPVEGKENE------YLLIWTTTPWTLPANLAVSAHPDYDYVKVKVEFNGREEY 259
PS+YV+F + + Y L+WTTTPWTLP+N A+ + +YV V++ ++E
Sbjct: 215 PSVYVRFALNPSSFDVKDKQIYALVWTTTPWTLPSNQAICYNASLEYVIVRLSDRNQDEL 274
Query: 260 WILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFKEKYEWAHRVI 319
+++A AL+ +K E+V+ G L L Y H + E F
Sbjct: 275 YLMASALMADFEANTQLKCEIVQHLSGELLSKLSYNHPIDKEQSNLPFFD---------- 324
Query: 320 LADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTEG-----KWKGIYV 374
A V +GTGLVHTAP HG EDF V +PV ++++G YT+ + K + +
Sbjct: 325 -ASHVQDSKGTGLVHTAPAHGPEDFLVSLTQKIPVKCFVNEEGTYTKEAPDFLRGKSV-L 382
Query: 375 KEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKDKIIKEN 434
+ + +++ + E +V + ++EH YP WR K P+I RA++QWF+ K+K +
Sbjct: 383 DQGNSLVLDRIAED--VVHSSKLEHSYPIDWRTKKPVIIRASEQWFINTEKLKTPAA-DA 439
Query: 435 DEKVTWYP----DWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWREL 490
E+V YP + K ++ W ISRQR WG+P+P+ S + V+ S L
Sbjct: 440 LEQVEIYPRANAEASKKALLTQLQKRPYWCISRQRAWGVPIPVLYSRESGKVVLNS--AL 497
Query: 491 VELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVV 550
+E + I+ +K +EE L PE L R + KD+ + D++
Sbjct: 498 IEHLCNLLRKEGSIDF-----WWVKSVEE-LVPEHLLRE------LHHEAKDLVKGTDIL 545
Query: 551 DVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVAFDTVPYR 610
D+WFDSG A LG + AD +EG DQ T WF S SI A + PY+
Sbjct: 546 DIWFDSGSTWSAVLGKDKI---------ADLYLEGYDQFTGWFQSSLLMSIAARECAPYK 596
Query: 611 RVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENLKFSWKGVE 670
+ +HG+ +DEKG KMSKSLGN+I P+++ ++ G D R+++ ++ S K ++
Sbjct: 597 ALFVHGFTVDEKGYKMSKSLGNVISPKQITKKYGTDALRWWVASHGTQHMSITVSDKLLQ 656
Query: 671 QVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDK-----WILSRVNSLISEV 725
Q N+ + T L K + ++L R DK ++LS++ SEV
Sbjct: 657 QAAE------NLCKIRGTMRYLKGVIGEKQSGEKL-IRTSDKSYLNRYLLSQLVEFESEV 709
Query: 726 ENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFDVLL 785
E +++ + + NF+ +S YV LI+ RL+ G+D + LA TL + L
Sbjct: 710 EKLYQAYEYNRVVACVQNFIANQVSAVYVHLIKDRLYC-GDDHELLAIRQTLTHCYQQLC 768
Query: 786 RLLAPFTPYIAEE 798
+ L P P++ EE
Sbjct: 769 KSLWPIVPFLVEE 781
>dbj|BAA95147.1| (D28500) mitochondrial isoleucine tRNA synthetase [Homo sapiens]
Length = 993
Score = 363 bits (923), Expect = 4e-99
Identities = 255/823 (30%), Positives = 405/823 (48%), Gaps = 92/823 (11%)
Query: 16 EEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRTM 75
E ++++ +E+Y +E RK ++ DGPPY +G H+G A NKI+KD+ RF M
Sbjct: 65 ELEIQQKCGFSELYSWQRE-RKVKTEFCLHDGPPYANGDPHVGHALNKILKDIANRFHMM 123
Query: 76 QGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIMTE 135
G + PG+D HGLPIE+KV LG + + + KK + FA ++
Sbjct: 124 NGSKIHFVPGWDCHGLPIEIKVLSELGREA-----QNLSAMEIRKKARSFAKAAIEKQKS 178
Query: 136 QFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHE 195
F GI DW+N Y T +Y T + ++KGL+ + + + W P TALAE E
Sbjct: 179 AFIRWGIMADWNNCYYTFDGKYEAKQLRTFYQMYDKGLVYRSYKPVFWSPSSRTALAEAE 238
Query: 196 VRGEYKLRK-DPSIYVKFP-----------VEGKENEYLLIWTTTPWTLPANLAVSAHPD 243
+ EY SIYVKFP ++G +L+WTT PWT+PAN AV P+
Sbjct: 239 L--EYNPEHVSRSIYVKFPLLKPSPKLASLIDGSSPVSILVWTTQPWTIPANEAVCYMPE 296
Query: 244 YDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYP 303
Y VK +G + ++LA V V + E + G +LE H L+ +
Sbjct: 297 SKYAVVKCSKSG--DLYVLAADKVASVASTLETTFETISTLSGVDLENGTCSHPLIPDK- 353
Query: 304 RQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGK 363
A ++ A+ VT+ +GTGLVHTAP HG ED+ V ++ LP+ +D+ G
Sbjct: 354 -----------ASPLLPANHVTMAKGTGLVHTAPAHGMEDYGVASQHNLPMDCLVDEDGV 402
Query: 364 YTEGKWKGIYVK----EADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQW 419
+T+ + K E +I+ L+ L+K ++ H YP+ WR K P++ RA+ QW
Sbjct: 403 FTDVAGPELQNKAVLEEGTDVVIKMLQTAKNLLKEEKLVHSYPYDWRTKKPVVIRASKQW 462
Query: 420 FLKISKVKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGD----WVISRQRYWGIPLPIWQ 475
F+ I+ +K KE +KV + P NG+ + D W ISRQR WG+P+P++
Sbjct: 463 FINITDIKTAA-KELLKKVKFIPGSAL----NGMVEMMDRRPYWCISRQRVWGVPIPVFH 517
Query: 476 SEDGEIYVVGSWRELVELAVAIEVNGERI--ELPESYEEKLKVIEEKLGPEDLHRPYVDA 533
+ + Y++ S + + +E +G I LP +V+ E GP+ L YV
Sbjct: 518 HKTKDEYLINS-QTTEHIVKLVEQHGSDIWWTLPPEQLLPKEVLSEVGGPDALE--YVPG 574
Query: 534 FIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWF 593
+D++D+WFDSG + L P + AD +EG+DQ+ WF
Sbjct: 575 -------------QDILDIWFDSGTSWSYVLPGPDQR--------ADLYLEGKDQLGGWF 613
Query: 594 YSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERA---------G 644
S S+ A PY+ V +HG+ L EKG+KMSKSLGN+I P+ VV G
Sbjct: 614 QSSLLTSVAARKRAPYKTVIVHGFTLGEKGEKMSKSLGNVIHPDVVVNGGQDQSKEPPYG 673
Query: 645 RDTFRFYMLWATNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDE 704
D R+++ +N + + + R ++ L N L ++ +F+P D
Sbjct: 674 ADVLRWWVA-DSNVFTEVAIGPSVLNAARDDISKLRN--TLRFLLGNVADFNP---ETDS 727
Query: 705 LPFREE---DKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRL 761
+P + D+++L + L +++ + + K R L F +LS +Y +I+ RL
Sbjct: 728 IPVNDMYVIDQYMLHLLQDLANKITELYKQYDFGKVVRLLRTFYTRELSNFYFSIIKDRL 787
Query: 762 WVEGE-DPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNL 803
+ E E DP + + L ++ DV++R AP P++AEE++Q++
Sbjct: 788 YCEKENDPKRRSCQTALVEILDVIVRSFAPILPHLAEEVFQHI 830
>pir||G82894 isoleucyl-tRNA synthetase UU410 [imported] - Ureaplasma urealyticum
>gi|6899398|gb|AAF30821.1|AE002138_8 (AE002138)
isoleucyl-tRNA synthetase [Ureaplasma urealyticum]
Length = 900
Score = 362 bits (920), Expect = 1e-98
Identities = 250/826 (30%), Positives = 412/826 (49%), Gaps = 92/826 (11%)
Query: 16 EEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRTM 75
E K+++FW E++IY K+ KD + DGPPY +G IH+G A NKI+KD ++ + M
Sbjct: 25 EPKIQQFWVEHQIYEKLLTKNKDKKPFILHDGPPYANGNIHIGHALNKILKDFVVSYHNM 84
Query: 76 QGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIMTE 135
Y PG+D HGLPIEV + + + L + V ++CK++AL + +
Sbjct: 85 NNYYSPYIPGWDTHGLPIEVALSKKIKL-------SNLSVNERREQCKKYALEQVNNQIQ 137
Query: 136 QFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHE 195
QF LG+ D+ Y+T+ + Y +KG + +D + + W +TALAE E
Sbjct: 138 QFLRLGMISDFKQRYLTLDHNYEIDQLKLFTYMLKKGFIYQDFKPVFWSWSSQTALAESE 197
Query: 196 VRGEYKLRKDPSIYVKFPVEGKENEY------LLIWTTTPWTLPANLAVSAHPDYDYVKV 249
+ EY R+ +IYVK V + + L+IWTTTPWTLPANLA++ HP+ Y +
Sbjct: 198 I--EYADRQSSAIYVKMKVVDHNDLFTDKPTSLVIWTTTPWTLPANLAIAIHPELVYSLI 255
Query: 250 KVEFNGREEYWILAKALVDKVLGEIGVKG-EVVEEFKGRELEGLRYVHILMDEYPRQKEF 308
+ + E +I+AK LV+ + ++G + + +++FK LE ++Y+
Sbjct: 256 EY----KNENYIIAKPLVETFVKKVGFEDYKWIKDFKANTLEKIKYI----------SPI 301
Query: 309 KEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKY---- 364
+K+ + VI+ ++V+ +GTGLVH AP G ED+ +KYG+ +D GKY
Sbjct: 302 SKKHAF---VIMDEYVSANDGTGLVHNAPAFGLEDYYACKKYGIETVVMIDQFGKYNALV 358
Query: 365 TEGKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKIS 424
+ + + ++ ++A+ I+ L + L+ I H H WR K P+++RAT QWF+ I
Sbjct: 359 NDLELENMFYEDANQVILNRLMNEHLLIHHEVITHSVAHDWRTKKPVMYRATKQWFVSIE 418
Query: 425 KVKDKIIK--ENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIY 482
K+ I++ ND K T + R + + +W ISRQR WG+P+P
Sbjct: 419 KILPNILQTLNNDVKSTSFRGIE--RMHEMIVNRKEWCISRQRVWGVPIP---------- 466
Query: 483 VVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFI----IKV 538
+ + N I E E + V+ EK G V+AF+ + +
Sbjct: 467 ------------MIFDENHNAIMDHELVENIINVLNEK-GVNAWFDLDVNAFLTPKYLSM 513
Query: 539 NGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQA 598
K + KD++DVWFDSG +S+ LG+ + +PAD +EG DQ WF S
Sbjct: 514 KNKTFYKEKDIMDVWFDSG-SSYNILGH------YNLNYPADVYLEGYDQYRGWFNSSLI 566
Query: 599 ASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNP 658
+ + PY+ + HG VLD +G KMSKS GN++ P +V + G D R ++ A +
Sbjct: 567 TGTILNNRAPYKYLVAHGMVLDGEGYKMSKSKGNVVDPLDVCKIYGADVLRLWI--ANSD 624
Query: 659 WEN-----LKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKW 713
++N + + E RR+ N L+ Y L+ L++F+P R+E+++
Sbjct: 625 YQNDTRISEEILKQNAEIYRRIRNTLFK-YSLS----ILNDFEPSV--DFSFNVRQEEQF 677
Query: 714 ILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLW-VEGEDPDKLA 772
+L+ N L +V E+F + L+N + DLS WY I+ ++ + DP +
Sbjct: 678 VLNEFNELHIKVIKAYENFDYQTVVK-LFNKFILDLSSWYFENIKDDMYCLAINDPIRKQ 736
Query: 773 AYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDW 818
++ + L L P P+ EE Y + ++ ES+ + D+
Sbjct: 737 IQSAVYWILKNSLIDLTPIIPHTTEEAY-SFLKDANKKESIRLEDF 781
>sp|P47587|SYI_MYCGE ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|1361704|pir||B64238 isoleucine--tRNA ligase (EC
6.1.1.5) - Mycoplasma genitalium
>gi|3844928|gb|AAC71570.1| (U39716) isoleucyl-tRNA
synthetase (ileS) [Mycoplasma genitalium]
Length = 895
Score = 361 bits (916), Expect = 3e-98
Identities = 267/912 (29%), Positives = 445/912 (48%), Gaps = 97/912 (10%)
Query: 16 EEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRTM 75
E+ FW + ++++K+K+ K DGPPY +G+IH+G A NKI+KD I+R
Sbjct: 24 EKNFHDFWKDKKVFQKLKKQNKGKQIKILHDGPPYANGSIHVGHALNKILKDFILRSWLY 83
Query: 76 QGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIMTE 135
+GY+V PG+D HGLPI E A+ K VE K C +FAL+ + + E
Sbjct: 84 EGYDVVFIPGWDCHGLPI----EHAVSKKNPSSYSNLSTVEK-RKLCHQFALSQIAVQKE 138
Query: 136 QFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHE 195
QF+ LG+ D+ N Y TI + +A +KGL+ +D + +W P T+LAE E
Sbjct: 139 QFQRLGLLNDFQNCYYTIDESFQFKELELFLQAIKKGLIFQDLKPTYWSPISRTSLAEAE 198
Query: 196 VRGEYKLRKDPSIYVKFPVEGK----ENEYLLIWTTTPWTLPANLAVSAHPDYDYVKVKV 251
+ EYK ++Y+ F V EN LL+WTTTPWTLP N A++ HPD+DY+
Sbjct: 199 I--EYKEVNSIALYLTFKVSKSDFLDENANLLVWTTTPWTLPTNQAIAIHPDFDYLL--- 253
Query: 252 EFNGREEYWILAKALVDKVLGEIGVKGEV-VEEFKGRELEGLRYVHILMDEYPRQKEFKE 310
F ++ +++ + L + ++ + +++FKG L+ Y H
Sbjct: 254 -FEYNQQKFVILEKLFEVFTNKLNWTNAIKLKKFKGSNLKNSSYSHCF------------ 300
Query: 311 KYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGL-PVYSPLDDQGKY----T 365
Y V++ V EGTG+VH++P G +DF + QK + V +D++G +
Sbjct: 301 -YNKVLPVLMGIHVVDNEGTGIVHSSPAFGIDDFYLCQKNKIKEVLISIDEKGVFNNLLN 359
Query: 366 EGKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISK 425
+ + + + +A+ II L++ + + I H+ PH WR KTP+I+RA+ Q F+K
Sbjct: 360 DKELENCFYLKANDLIINRLKQNNSFIFSEVISHREPHDWRSKTPVIYRASKQLFIKTKS 419
Query: 426 VKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVG 485
+K K +K+ +V + ++R + +W ISRQR WG+P+PI V
Sbjct: 420 IK-KQLKKQINQVNFLNSKNQLRLKEMLLQRDEWCISRQRVWGLPIPI---------VYA 469
Query: 486 SWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGK---D 542
+ + L++ + + + +K + +K G + V F+ K
Sbjct: 470 NNKPLLDFS--------------TIQYTIKQL-KKHGIDSWFEKDVTCFLKPDKTKKWVK 514
Query: 543 MRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIV 602
+ D +DVWFDSG +S+ L + + AD +EG DQ WF S I+
Sbjct: 515 YHKEIDTLDVWFDSG-SSYNVLEINKYGSI------ADLYIEGSDQYRGWFNSSSNCGII 567
Query: 603 AFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATN-PWE- 660
D +P++ + HG+ LDE G+KMSKSLGNI+ P ++ ++ G D R LW N W+
Sbjct: 568 QNDLIPFKSLVSHGFTLDENGNKMSKSLGNIVDPLKICDQYGADILR---LWVANTDWQI 624
Query: 661 ----NLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILS 716
+ + EQ RR+ N L ++L +++ F+ + D+ F EDK ++
Sbjct: 625 DNKIGVNILKQVAEQYRRIRNSLLR-FILG----NINGFNFTSM--DDYKFSLEDKIVIH 677
Query: 717 RVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGE-DPDKLAAYY 775
+ NSL+ ++E +E + + + FV+ LS WY +I+ L+ + + +P++LA
Sbjct: 678 KTNSLVEQIEKFLEKYNFLGCLKVINKFVLW-LSSWYFEIIKDTLYCDAKNNPNRLAKQA 736
Query: 776 TLWKVFDVLLRLLAPFTPYIAEEIYQNLI---RPFTNVESVHMLDWPKVDEKAIDEELER 832
L +F L+ L F P+ AE+ ++N +P SV++ P V + A + L
Sbjct: 737 VLNYIFTQLISFLNIFIPHTAEDAWKNYSFNKKPI----SVNLFTKPTVFKVANSKNLGN 792
Query: 833 EMEFIRRIVEAGSAARQRAKIKLRYPV-RRIIIETEDETVKKAVERLNRILRDQLNAKEV 891
+ I A A ++ K++ + + IE KK ++L L LN V
Sbjct: 793 IYKTFTSIKNA--AFKEIEKLRKEGLISKNNQIELTVGINKKIPKKLKDNLALWLNVNSV 850
Query: 892 KVGRVERELTIK 903
+ E E+ +K
Sbjct: 851 NLTNNENEIKVK 862
>sp|Q27707|SYI_NOSLO ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|598336|gb|AAC41564.1| (L37097) isoleucyl-tRNA
synthetase [Nosema locustae]
Length = 628
Score = 347 bits (881), Expect = 4e-94
Identities = 219/686 (31%), Positives = 357/686 (51%), Gaps = 74/686 (10%)
Query: 86 YDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIMTEQFKMLGIWMD 145
+D HG+P+E ++++ALG+ K+I + +G+ + K+C++ L K K +G W+D
Sbjct: 1 WDRHGVPVEYEIDKALGITGVKDIHD-MGIRKYNKECRKIVLRYTKEWEAVVKRMGRWID 59
Query: 146 WDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHEVRGEYKLRKD 205
+ N Y T+ ++ES W K +EKG + + RV+ + C T L+ E YK D
Sbjct: 60 FRNGYRTMDRSFMESIWHIFKMLYEKGSVYRGHRVMPYSTACSTPLSNFEANQNYKDVSD 119
Query: 206 PSIYVKFPVEGKENEY---LLIWTTTPWTLPANLAVSAHPDYDYVKVKVEFNGREEYWIL 262
PSI V FP+ Y L+ WTTTPWTLP+++A+ + + Y F + ++I+
Sbjct: 120 PSILVAFPLRKPFKGYSLSLVAWTTTPWTLPSHMAILVNQSFIY----AIFRLKSAFFIM 175
Query: 263 AKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDE-YPRQKEFKEKYEWAHRVILA 321
+ V+ + V+ E KG EL +H+ D+ + ++EK RV A
Sbjct: 176 QRDRVNVYFKD----AVVISEVKGHEL-----LHLEHDQPFMYYNHYREK--GFFRVYHA 224
Query: 322 DFVTLEEGTGLVHTAPGHGEEDFEVGQKYGL-----PVYSPLDDQGKYTE--GKWKGIYV 374
DFV+ +GTG+VH +PG GE+D++ GL + SPLD+ G++ E ++KG++V
Sbjct: 225 DFVSEIDGTGVVHCSPGFGEDDYKAMTMPGLIKENELLPSPLDENGRFNEEVPEYKGMHV 284
Query: 375 KEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKDKIIKEN 434
K+AD II+ L +K ++ G++ H+YP CWR TPLI++ WF+++ + +++ E+
Sbjct: 285 KDADQSIIKDLGKK--ILYEGKVYHRYPFCWRSDTPLIYKLVPNWFVRVKREIPRLL-ES 341
Query: 435 DEKVTWYPDWV-KIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVEL 493
+ + W P+ + + +F N + ++ DW ISR R+WG P+P+W DG+ +GS EL L
Sbjct: 342 NSTINWIPESIGEHKFKNWLSEARDWSISRNRFWGTPIPLWHC-DGKYICIGSIEELSRL 400
Query: 494 AVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVW 553
+G +I +D+HR VD +I +G+ RR+++V D W
Sbjct: 401 ------SGRKI-------------------DDIHRENVDDVVICKDGEKYRRIEEVFDCW 435
Query: 554 FDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVAFDTVPYRRVA 613
F+SG +A +P E PADF+ EG DQ WFY+ S V +R
Sbjct: 436 FESGCMPYAQRHWP--FECDNLCLPADFVAEGVDQTRGWFYTMHVISTVLLAKPRFRNCI 493
Query: 614 MHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNP---WENLKFSWKGVE 670
++G VL KMSK L N P +V+ R D+ R Y++ ++P EN+ FS +GV
Sbjct: 494 VNGIVLASDKKKMSKRLKNYPDPMDVINRYSADSLRLYLI--SSPVVMAENMCFSEEGVG 551
Query: 671 QVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISEVENGIE 730
+V + L I W Y Y N ++ D WIL+ +N+ ++V+ +
Sbjct: 552 EVLKTLLIPW--YNCIYFYSECPNAGDQEQT-------RMDDWILNTLNTFGNKVKRDM- 601
Query: 731 SFYLTKATRALYNFVVEDLSRWYVRL 756
S Y+ + V DLS WY+RL
Sbjct: 602 SKYMLQGVMGYATSFVNDLSNWYIRL 627
>gi|8922356 hypothetical protein FLJ10326 [Homo sapiens]
>gi|7022287|dbj|BAA91544.1| (AK001188) unnamed protein
product [Homo sapiens]
Length = 764
Score = 327 bits (830), Expect = 4e-88
Identities = 233/764 (30%), Positives = 370/764 (47%), Gaps = 91/764 (11%)
Query: 75 MQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIMT 134
M G + PG+D HGLPIE+KV LG + + + KK + FA ++
Sbjct: 1 MNGSKIHFVPGWDCHGLPIEIKVLSELGREA-----QNLSAMEIRKKARSFAKAAIEKQK 55
Query: 135 EQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEH 194
F GI DW+N Y T +Y T + ++KGL+ + + + W P TALAE
Sbjct: 56 SAFIRWGIMADWNNCYYTFDGKYEAKQLRTFYQMYDKGLVYRSYKPVFWSPSSRTALAEA 115
Query: 195 EVRGEYKLRK-DPSIYVKFP-----------VEGKENEYLLIWTTTPWTLPANLAVSAHP 242
E+ EY SIYVKFP ++G +L+WTT PWT+PAN AV P
Sbjct: 116 EL--EYNPEHVSRSIYVKFPLLKPSPKLASLIDGSSPVSILVWTTQPWTIPANEAVCYMP 173
Query: 243 DYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEY 302
+ Y VK +G + ++LA V V + E + G +LE H L+ +
Sbjct: 174 ESKYAVVKCSKSG--DLYVLAADKVASVASTLETTFETISTLSGVDLENGTCSHPLIPDK 231
Query: 303 PRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQG 362
A ++ A+ VT+ +GTGLVHTAP HG ED+ V ++ LP+ +D+ G
Sbjct: 232 ------------ASPLLPANHVTMAKGTGLVHTAPAHGMEDYGVASQHNLPMDCLVDEDG 279
Query: 363 KYTEGKWKGIYVK----EADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQ 418
+T+ + K E +I+ L+ L+K ++ H YP+ WR K P++ RA+ Q
Sbjct: 280 VFTDVAGPELQNKAVLEEGTDVVIKMLQTAKNLLKEEKLVHSYPYDWRTKKPVVIRASKQ 339
Query: 419 WFLKISKVKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGD----WVISRQRYWGIPLPIW 474
WF+ I+ +K KE +KV + P NG+ + D W ISRQR WG+P+P++
Sbjct: 340 WFINITDIKTAA-KELLKKVKFIPGSAL----NGMVEMMDRRPYWCISRQRVWGVPIPVF 394
Query: 475 QSEDGEIYVVGSWRELVELAVAIEVNGERI--ELPESYEEKLKVIEEKLGPEDLHRPYVD 532
+ + Y++ S + + +E +G I LP +V+ E GP+ L YV
Sbjct: 395 HHKTKDEYLINS-QTTEHIVKLVEQHGSDIWWTLPPEQLLPKEVLSEVGGPDALE--YVP 451
Query: 533 AFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKW 592
+D++D+WFDSG + L P + AD +EG+DQ+ W
Sbjct: 452 G-------------QDILDIWFDSGTSWSYVLPGPDQR--------ADLYLEGKDQLGGW 490
Query: 593 FYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERA--------- 643
F S S+ A PY+ V +HG+ L EKG+KMSKSLGN+I P+ VV
Sbjct: 491 FQSSLLTSVAARKRAPYKTVIVHGFTLGEKGEKMSKSLGNVIHPDVVVNGGQDQSKEPPY 550
Query: 644 GRDTFRFYMLWATNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPD 703
G D R+++ +N + + + R ++ L N L ++ +F+P D
Sbjct: 551 GADVLRWWVA-DSNVFTEVAIGPSVLNAARDDISKLRN--TLRFLLGNVADFNP---ETD 604
Query: 704 ELPFREE---DKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKR 760
+P + D+++L + L +++ + + K R L F +LS +Y +I+ R
Sbjct: 605 SIPVNDMYVIDQYMLHLLQDLANKITELYKQYDFGKVVRLLRTFYTRELSNFYFSIIKDR 664
Query: 761 LWVEGE-DPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNL 803
L+ E E DP + + L ++ DV++R AP P++AEE++Q++
Sbjct: 665 LYCEKENDPKRRSCQTALVEILDVIVRSFAPILPHLAEEVFQHI 708
>gi|11426198 hypothetical protein FLJ10326 [Homo sapiens]
Length = 871
Score = 327 bits (830), Expect = 4e-88
Identities = 233/764 (30%), Positives = 370/764 (47%), Gaps = 91/764 (11%)
Query: 75 MQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIMT 134
M G + PG+D HGLPIE+KV LG + + + KK + FA ++
Sbjct: 1 MNGSKIHFVPGWDCHGLPIEIKVLSELGREA-----QNLSAMEIRKKARSFAKAAIEKQK 55
Query: 135 EQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEH 194
F GI DW+N Y T +Y T + ++KGL+ + + + W P TALAE
Sbjct: 56 SAFIRWGIMADWNNCYYTFDGKYEAKQLRTFYQMYDKGLVYRSYKPVFWSPSSRTALAEA 115
Query: 195 EVRGEYKLRK-DPSIYVKFP-----------VEGKENEYLLIWTTTPWTLPANLAVSAHP 242
E+ EY SIYVKFP ++G +L+WTT PWT+PAN AV P
Sbjct: 116 EL--EYNPEHVSRSIYVKFPLLKPSPKLASLIDGSSPVSILVWTTQPWTIPANEAVCYMP 173
Query: 243 DYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEY 302
+ Y VK +G + ++LA V V + E + G +LE H L+ +
Sbjct: 174 ESKYAVVKCSKSG--DLYVLAADKVASVASTLETTFETISTLSGVDLENGTCSHPLIPDK 231
Query: 303 PRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQG 362
A ++ A+ VT+ +GTGLVHTAP HG ED+ V ++ LP+ +D+ G
Sbjct: 232 ------------ASPLLPANHVTMAKGTGLVHTAPAHGMEDYGVASQHNLPMDCLVDEDG 279
Query: 363 KYTEGKWKGIYVK----EADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQ 418
+T+ + K E +I+ L+ L+K ++ H YP+ WR K P++ RA+ Q
Sbjct: 280 VFTDVAGPELQNKAVLEEGTDVVIKMLQTAKNLLKEEKLVHSYPYDWRTKKPVVIRASKQ 339
Query: 419 WFLKISKVKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGD----WVISRQRYWGIPLPIW 474
WF+ I+ +K KE +KV + P NG+ + D W ISRQR WG+P+P++
Sbjct: 340 WFINITDIKTAA-KELLKKVKFIPGSAL----NGMVEMMDRRPYWCISRQRVWGVPIPVF 394
Query: 475 QSEDGEIYVVGSWRELVELAVAIEVNGERI--ELPESYEEKLKVIEEKLGPEDLHRPYVD 532
+ + Y++ S + + +E +G I LP +V+ E GP+ L YV
Sbjct: 395 HHKTKDEYLINS-QTTEHIVKLVEQHGSDIWWTLPPEQLLPKEVLSEVGGPDALE--YVP 451
Query: 533 AFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKW 592
+D++D+WFDSG + L P + AD +EG+DQ+ W
Sbjct: 452 G-------------QDILDIWFDSGTSWSYVLPGPDQR--------ADLYLEGKDQLGGW 490
Query: 593 FYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERA--------- 643
F S S+ A PY+ V +HG+ L EKG+KMSKSLGN+I P+ VV
Sbjct: 491 FQSSLLTSVAARKRAPYKTVIVHGFTLGEKGEKMSKSLGNVIHPDVVVNGGQDQSKEPPY 550
Query: 644 GRDTFRFYMLWATNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPD 703
G D R+++ +N + + + R ++ L N L ++ +F+P D
Sbjct: 551 GADVLRWWVA-DSNVFTEVAIGPSVLNAARDDISKLRN--TLRFLLGNVADFNP---ETD 604
Query: 704 ELPFREE---DKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKR 760
+P + D+++L + L +++ + + K R L F +LS +Y +I+ R
Sbjct: 605 SIPVNDMYVIDQYMLHLLQDLANKITELYKQYDFGKVVRLLRTFYTRELSNFYFSIIKDR 664
Query: 761 LWVEGE-DPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNL 803
L+ E E DP + + L ++ DV++R AP P++AEE++Q++
Sbjct: 665 LYCEKENDPKRRSCQTALVEILDVIVRSFAPILPHLAEEVFQHI 708
>emb|CAB75396.1| (AL139298) valyl tRNA synthetase [Streptomyces coelicolor A3(2)]
Length = 874
Score = 323 bits (818), Expect = 9e-87
Identities = 230/837 (27%), Positives = 384/837 (45%), Gaps = 123/837 (14%)
Query: 9 EYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDM 68
+Y P ++E ++ + W E + + + D P Y + PP V+G++HLG A+ + D
Sbjct: 19 QYTPAEVEGQLYERWVERGYFEA--DAKSDKPPYTVVIPPPNVTGSLHLGHAFEHTLIDA 76
Query: 69 IIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALN 128
+ R + MQGY QPG D G+ + VE+ LG + K + +G E F+++ ++
Sbjct: 77 LTRRKRMQGYETLWQPGMDHAGIATQNVVERELGKEGKSRHD--LGREAFVERVWQWKSE 134
Query: 129 NLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCE 188
+ ++ Q + LG + W T+ ++ KR ++ L+ + +R+++WCPRC
Sbjct: 135 SGGQISGQMRRLGDAVAWSRERFTMDEGLSQAVQTIFKRLYDDELIYRAERIINWCPRCL 194
Query: 189 TALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVK 248
TA+++ EV EY+ + +K+ G+ +E +++ TT T+ + AV+ HP+
Sbjct: 195 TAISDIEV--EYQDDDGELVSMKY---GEGDETIVVATTRAETMLGDTAVAVHPE----- 244
Query: 249 VKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEF 308
E Y L L+ L + R + ++ DE+
Sbjct: 245 -------DERYKHLVGKLIKLPLTD-------------------RSIPVVADEH------ 272
Query: 309 KEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYT-EG 367
V E GTG V P H DFE+GQ++GLP + +D+ T G
Sbjct: 273 ---------------VDPEFGTGAVKVTPAHDPNDFEIGQRHGLPAIAVMDEHAVITAHG 317
Query: 368 KWKGIYVKEADPKIIEHLREKGYLV-KAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKV 426
++G EA I+ LR +G +V + H HC RCKT + R + QW++K+ +
Sbjct: 318 PFQGQDRLEARSAIVAALRAEGRIVAEKRPYVHSVGHCSRCKTTIEPRLSMQWWVKVGPL 377
Query: 427 -KDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVG 485
K D KV +P ++ R+ + V + DW ISRQ +WG +P+W +GE+ VG
Sbjct: 378 AKAAGDAVRDGKVKIHPQEMEKRYFDWVDNLHDWCISRQLWWGHRIPVWYGPEGEVVCVG 437
Query: 486 SWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRR 545
E P S G+ +
Sbjct: 438 PGEE-----------------PPS------------------------------GEGWYQ 450
Query: 546 VKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVAFD 605
DV+D WF SG+ +++LG+P E K +P +V G D + W + A D
Sbjct: 451 DSDVLDTWFSSGLWPFSTLGWPEQTESLAKFYPNSVLVTGYDILFFWVARMMMFGLYAMD 510
Query: 606 -TVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENLKF 664
T P+ +A+HG V D+ G KMSKS GN++ P + +++ G D RF + NP ++
Sbjct: 511 GTPPFHTIALHGMVRDQNGKKMSKSFGNVVNPLDWMDKYGSDALRFTLARGANPGVDVPI 570
Query: 665 SWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISE 724
V+ R N +WN A+ + ++ PD D+WILSR+NS+++E
Sbjct: 571 GEDWVQGSRNFANKIWN----ATRFALMNGATVEGPLPDASRMSSTDRWILSRLNSVVAE 626
Query: 725 VENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFDVL 784
V+ E + K + AL++F +++ WYV L + GE + + L +V DV
Sbjct: 627 VDAYYEDYQFAKLSDALFHFAWDEVFDWYVELSKTTFQAGGEAAE--VSKRVLGEVLDVT 684
Query: 785 LRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREMEFIRRIV 841
LRLL P P++ E ++ L T ESV + +WP D D ERE+E ++ ++
Sbjct: 685 LRLLHPVVPFVTETLWTTL----TGGESVVIAEWP-TDSGFRDAGAEREIETVQSVI 736
>gi|6325217 nuclear encoded mitochondrial isoleucyl-tRNA synthetase; Ism1p
[Saccharomyces cerevisiae]
>gi|1711634|sp|P48526|SYIM_YEAST ISOLEUCYL-TRNA
SYNTHETASE, MITOCHONDRIAL (ISOLEUCINE--TRNA LIGASE)
(ILERS) >gi|2132320|pir||S62035 isoleucine--tRNA ligase
(EC 6.1.1.5), mitochondrial - yeast (Saccharomyces
cerevisiae) >gi|1171418|gb|AAB68180.1| (U44030) Ism1p:
mitochondrial isoleucyl-tRNA synthetase [Saccharomyces
cerevisiae]
Length = 1002
Score = 318 bits (806), Expect = 2e-85
Identities = 254/840 (30%), Positives = 408/840 (48%), Gaps = 101/840 (12%)
Query: 13 KKLEEKVEKFWSENEIYRKVKELRKDGPKYYFL-DGPPYVSGAIHLGTAWNKIIKDMIIR 71
++L + E+F N K++ +++ K + L DGPPY +G +HLG A NKI+KD+I R
Sbjct: 60 EQLRDFFEEFSKLNTTDEKLEFIKE---KLFILHDGPPYANGELHLGHALNKILKDIINR 116
Query: 72 FRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLK 131
++ QG ++ +PG+D HGLPIE+K + L + E I + A +K
Sbjct: 117 YQLSQGKYIFYKPGWDCHGLPIEIKALKDLSAQQ----IESISPLKIRSMALKHAQKAIK 172
Query: 132 IMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETAL 191
E F+ I DW+ PY+T+ +Y + K +E+GL+++ + ++W TAL
Sbjct: 173 RQRETFQHFAILTDWETPYLTMDKDYEINQLNIFKEMYERGLIKRQNKPVYWGTETRTAL 232
Query: 192 AEHEVRGEY-KLRKDPSIYVKFPVEGKENE--------------YLLIWTTTPWTLPANL 236
AE E+ EY + K + YVKFP+E K Y LIWT+TPWTL +N
Sbjct: 233 AEGEL--EYNENHKSIAAYVKFPLEKKSQMDLCKKLGITNNLPIYCLIWTSTPWTLLSNR 290
Query: 237 AVSAHPDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVH 296
A+ + D+ Y +++ E ++ +DK LG E +++F+G L GL Y +
Sbjct: 291 AICFNQDFSYSLLRL----NSELILVETGSIDK-LGLTTNSFETIKQFQGTHLNGLYYQN 345
Query: 297 ILMDEYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYS 356
+L+D+ K + AH VT GTGLVHTAPGHG++D+ +G + GL +YS
Sbjct: 346 LLVDD----KVGRPLLHGAH-------VTSGTGTGLVHTAPGHGQDDYLIGIQNGLEIYS 394
Query: 357 PLDDQGKY--------------TEGK-WKGIYVKEADPK--IIEHLREKGYLVKAGEIEH 399
P+D QG+Y EG KG V +A+ I+ L + L K+ E H
Sbjct: 395 PVDHQGRYQLNELPQSVRSIVRDEGDLTKGRQVLDAETAKIILCKLSDLNLLYKSHEYTH 454
Query: 400 KYPHCWRCKTPLIFRATDQWFLKISKVKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDW 459
YP+ WR K P+I RAT QWF + VK+ + E+ +V + P R + ++ +W
Sbjct: 455 SYPYDWRSKKPVIIRATPQWFADLHDVKN-LALESISRVKFCPKRGYSRLSSFMKSRNEW 513
Query: 460 VISRQRYWGIP-LPIWQSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIE 518
ISRQR WGIP L ++ + + ++ S E+ LA AIE ++ + + +K ++
Sbjct: 514 CISRQRSWGIPILSFYKKSEPDSVLMNS--EI--LAHAIEKIKQK-GINAWFNDKDNDMK 568
Query: 519 EKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWP 578
E L PE H + R +D +DVWFDSG +SW+ + K L P
Sbjct: 569 EWL-PEKYHDV----------AHEYCRSQDTMDVWFDSG-SSWSVIKDFYEKSLKLSKLP 616
Query: 579 A---DFIVEGEDQVTKWFYSQQAASIVAFD--TVPYRRVAMHGYVLDEKGDKMSKSLGNI 633
+ +EG DQ WF S + + + PY V HG+ LDE G KMSKS+GN
Sbjct: 617 SPLYQVCLEGSDQHRGWFQSSLLTKVASSNVPVAPYEEVITHGFTLDENGLKMSKSVGNT 676
Query: 634 IRPEEVVE--------RAGRDTFRFYMLWATNPWENLKFS---WKGVEQVRRMLNILWNV 682
I PE ++ G D R Y++ +N ++ K V + + + + +
Sbjct: 677 ISPEAIIRGDENLGLPALGVDGLR-YLIAQSNFTTDIVAGPTVMKHVGEALKKVRLTFR- 734
Query: 683 YVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISEVENGIESFYLTKATRALY 742
Y+L++ S D L P E R D++ L ++N L+ + + +K L
Sbjct: 735 YLLSNLQKSQD----FNLLPIE-QLRRVDQYTLYKINELLETTREHYQKYNFSKVLITLQ 789
Query: 743 NFVVEDLSRWYVRLIRKRLWV-EGEDPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQ 801
+ +LS +Y + + L+ + + TL + + +LAP P + +E+++
Sbjct: 790 YHLNNELSAFYFDISKDILYSNQISSLARRQVQTTLVHILNAYRAILAPILPVMVQEVWK 849
>gb|AAG20602.1| (AE005130) valyl-tRNA synthetase; ValS [Halobacterium sp. NRC-1]
Length = 881
Score = 316 bits (801), Expect = 9e-85
Identities = 260/964 (26%), Positives = 428/964 (43%), Gaps = 128/964 (13%)
Query: 10 YDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMI 69
YDP +E K + W E ++YR + + +Y PPY SG +HLG A D +
Sbjct: 8 YDPNSIEPKWQDEWQERDVYRF--DPSESDTQYVIDTPPPYPSGNLHLGHALGWSYIDFV 65
Query: 70 IRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNN 129
R+R ++G V G+D HGLP EVKVE+ + + + F + C ++ +
Sbjct: 66 ARYRRLKGDAVLFPQGWDCHGLPTEVKVEEVNDIH-----RTDVPSDEFREMCIDWTEDR 120
Query: 130 LKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCET 189
+ M + LG DWD+ Y T+ EY + + G++ +D+ ++WCPRCET
Sbjct: 121 IDEMKATMQELGFSQDWDSEYRTMDPEYWGKTQESFSEMADAGMVYRDEHPVNWCPRCET 180
Query: 190 ALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVKV 249
A+A+ EV E R+ YV F +G +N + I TT P L A + + PD D
Sbjct: 181 AIADAEV--ENIDREGTLHYVTF--DGVDNGDIEIATTRPELLAACVGIVVSPDDD---- 232
Query: 250 KVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFK 309
+ IG EV G+++E
Sbjct: 233 -------------------RYADRIGDTFEV--PLFGQDVE------------------- 252
Query: 310 EKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTE--G 367
++ D V + G+G V ++D E + L + + + G E G
Sbjct: 253 --------LLADDDVDADFGSGAVMVCTFGDKQDVEWWMDHDLDLRTVFTEDGHLNEAAG 304
Query: 368 KWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVK 427
++ G+ + +A ++ E L ++GYL E CWRC T + + +QWF+++ +
Sbjct: 305 EFAGLAIDDAKTQVAEELDDQGYLNDTEPTEQSVGSCWRCDTAIEILSKEQWFVEVDQ-- 362
Query: 428 DKIIKENDEKVTWYPDWVKIRFDNGVRDSG-DWVISRQRYWGIPLPIWQSEDGEIYVVGS 486
D+I+ + W P+ + R DWVISRQR + P+P W+ + G
Sbjct: 363 DRILDAAAD-AEWVPEHMHDRLVEWTEGMDWDWVISRQRVFATPIPAWECNE-----CGH 416
Query: 487 WRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRV 546
W E+ G + E+ P V+A + G D
Sbjct: 417 W----------EIAGREQAPVDPTEDD---------------PAVEA-CPECGGDDWAGE 450
Query: 547 KDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVAFDT 606
DV+D W DS I G+P L ++ D +G D + W + + D
Sbjct: 451 TDVMDTWMDSSITPLHLSGWPEGTTL-DEFESVDLRPQGHDIIRTWAFYTLLRTGALTDE 509
Query: 607 VPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENLKFSW 666
P+ V ++G V E G+KMSKS GN ++P+E + D R + P +++F W
Sbjct: 510 QPWDDVLVNGMVFGEDGNKMSKSRGNFVQPDEAIAEYSADAVRQALALGGRPGSDVQFQW 569
Query: 667 KGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISEVE 726
K V+ R L LWN+ T S +FD + +R+ D+W+LS ++++ +V+
Sbjct: 570 KEVKSASRFLTKLWNI-----TKFSTGHFDEDTPAIQDPAYRDADRWLLSELSTVCEDVD 624
Query: 727 NGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFDVLLR 786
+ + +A R+L F EDL+ YV L++ RL+ G ++ AA +TL+ + R
Sbjct: 625 EAMSEYRFDRALRSLREFAWEDLADDYVELVKGRLY-NGRPGERAAAEHTLYTAVTAVTR 683
Query: 787 LLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEEL--EREMEFIRRIVEAG 844
LLAPF+P+ EEI+Q+L P T SVH +P V+ + D EL +R E R I
Sbjct: 684 LLAPFSPHTTEEIWQSL--PGTE-GSVHAATFPSVEYRDADAELAGKRIAEVAREI---- 736
Query: 845 SAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRI-LRDQLNAK-EVKVGRVERELT- 901
A + + L + R+ + +D A RL+ L + +NA + GR + EL
Sbjct: 737 RAWKSDQGMPLNADLDRVELYFDDSDDDAA--RLDTYDLSETVNAPIRLIDGRPDVELVP 794
Query: 902 --IKPNFAKLGPEFKGDAKIIAKWINENG-----RELYEKGELTVEIDGKTFHLTREHII 954
+ + +++GPEF+ DA + + I +++ +TVE DG++F L + +
Sbjct: 795 VDVDGDDSEIGPEFRSDAGTVMEAIAAADPAAIQAQIHSGDTVTVEADGESFDLDADWLT 854
Query: 955 VEEK 958
V E+
Sbjct: 855 VTEE 858
>gb|AAA64890.1| (L38957) mitochondrial isoleucyl-tRNA synthetase [Saccharomyces
cerevisiae]
Length = 1002
Score = 315 bits (799), Expect = 2e-84
Identities = 255/840 (30%), Positives = 408/840 (48%), Gaps = 101/840 (12%)
Query: 13 KKLEEKVEKFWSENEIYRKVKELRKDGPKYYFL-DGPPYVSGAIHLGTAWNKIIKDMIIR 71
++L + E+F N K++ +++ K + L DGPPY +G +HLG A NKI+KD+I R
Sbjct: 60 EQLRDFFEEFSKLNTTDEKLEFIKE---KLFILHDGPPYANGELHLGHALNKILKDIINR 116
Query: 72 FRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLK 131
++ QG ++ +PG+D HGLPIE+K + L + E I + A +K
Sbjct: 117 YQLSQGKYIFYKPGWDCHGLPIEIKALKDLSAQQ----IESISPLKIRSMALKHAQKAIK 172
Query: 132 IMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETAL 191
E F+ I DW+ PY+T+ +Y + K +E+GL+++ + ++W TAL
Sbjct: 173 RQRETFQHFAILTDWETPYLTMDKDYEINQLNIFKEMYERGLIKRQNKPVYWGTETRTAL 232
Query: 192 AEHEVRGEY-KLRKDPSIYVKFPVEGKENE--------------YLLIWTTTPWTLPANL 236
AE E+ EY + K + YVKFP+E K Y LIWT+TPWTL +N
Sbjct: 233 AEGEL--EYNENHKSIAAYVKFPLEKKSQMDLCKKLGITNNLPIYCLIWTSTPWTLLSNR 290
Query: 237 AVSAHPDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVH 296
A+ + D+ Y +++ E ++ +DK LG E +++F+G L GL Y +
Sbjct: 291 AICFNQDFSYSLLRL----NSELILVETGSIDK-LGLTTNSFETIKQFQGTHLNGLYYQN 345
Query: 297 ILMDEYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYS 356
+L+D+ K + AH VT GTGLVHTAPGHG++D+ +G + GL +YS
Sbjct: 346 LLVDD----KVGRPLLHGAH-------VTSGTGTGLVHTAPGHGQDDYLIGIQNGLEIYS 394
Query: 357 PLDDQGKY--------------TEGK-WKGIYVKEAD-PKIIE-HLREKGYLVKAGEIEH 399
P+D QG+Y EG KG V +A+ KII L + L K+ E H
Sbjct: 395 PVDHQGRYQLNELPQSVRSIVRDEGDLTKGRQVLDAETAKIIPCKLSDLNLLYKSHEYTH 454
Query: 400 KYPHCWRCKTPLIFRATDQWFLKISKVKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDW 459
YP+ WR K P+I RAT QWF + VK+ + E+ +V + P R + ++ +W
Sbjct: 455 SYPYDWRSKKPVIIRATPQWFADLHDVKN-LALESISRVKFCPKRGYSRLSSFMKSRNEW 513
Query: 460 VISRQRYWGIP-LPIWQSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIE 518
ISRQR WGIP L ++ + + ++ S E+ LA AIE ++ + + +K ++
Sbjct: 514 CISRQRSWGIPILSFYKKSEPDSVLMNS--EI--LAHAIEKIKQK-GINAWFNDKDNDMK 568
Query: 519 EKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWP 578
E L PE H + R +D +DVWFDSG +SW+ + K L P
Sbjct: 569 EWL-PEKYHDV----------AHEYCRSQDTMDVWFDSG-SSWSVIKDFYEKSLKLSKLP 616
Query: 579 A---DFIVEGEDQVTKWFYSQQAASIVAFD--TVPYRRVAMHGYVLDEKGDKMSKSLGNI 633
+ +EG DQ WF S + + + PY V HG+ LDE G KMSK +GN
Sbjct: 617 SPLYQVCLEGSDQHRGWFQSSLLTKVASSNVPVAPYEEVITHGFTLDENGLKMSKLVGNT 676
Query: 634 IRPEEVVE--------RAGRDTFRFYMLWATNPWENLKFS---WKGVEQVRRMLNILWNV 682
I PE ++ G D R Y++ +N ++ K V + + + + +
Sbjct: 677 ISPEAIIRGDENLGLPALGVDGLR-YLIAQSNFTTDIVAGPTVMKHVGEALKKVRLTFR- 734
Query: 683 YVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISEVENGIESFYLTKATRALY 742
Y+L++ S D L P E R D++ L ++N L+ + + +K L
Sbjct: 735 YLLSNLQKSQD----FNLLPIE-QLRRVDQYTLYKINELLETTREHYQKYNFSKVLITLQ 789
Query: 743 NFVVEDLSRWYVRLIRKRLWV-EGEDPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQ 801
+ +LS +Y + + L+ + + TL + + +LAP P + +E+++
Sbjct: 790 YHLNNELSAFYFDISKGILYSNQISSLARRQVQTTLVHILNAYRAILAPILPVMVQEVWK 849
>sp|Q05873|SYV_BACSU VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|541424|pir||S41420 valine--tRNA ligase (EC 6.1.1.9)
valS - Bacillus subtilis >gi|452309|emb|CAA54458.1|
(X77239) valyl-tRNA synthetase [Bacillus subtilis]
>gi|2635274|emb|CAB14769.1| (Z99118) valyl-tRNA
synthetase [Bacillus subtilis]
Length = 880
Score = 313 bits (794), Expect = 6e-84
Identities = 245/979 (25%), Positives = 436/979 (44%), Gaps = 132/979 (13%)
Query: 9 EYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDM 68
+YDP +E+ FW + + + + K+ Y + PP V+G +HLG AW+ ++D+
Sbjct: 11 KYDPAAVEKDRYDFWLKGKFFEAGSDQTKE--PYSVVIPPPNVTGRLHLGHAWDTTLQDI 68
Query: 69 IIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALN 128
+ R + MQGY+V PG D G+ + KVE L + K + +G E F+++ ++
Sbjct: 69 VTRMKRMQGYDVLWLPGMDHAGIATQAKVEAKLREEGKSRYD--LGREKFLEETWKWKEE 126
Query: 129 NLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCE 188
+ Q+ LG+ +D+ T+ ++ + +EKGL+ + + +++W P +
Sbjct: 127 YADFIRSQWAKLGLGLDYSRERFTLDEGLSKAVREVFVKLYEKGLIYRGEYIINWDPATK 186
Query: 189 TALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVK 248
TAL++ EV YK + ++ +P+ + I TT P T+ + AV+ HP+ +
Sbjct: 187 TALSDIEVI--YKDVQGAFYHMSYPLADGSGS-IEIATTRPETMLGDTAVAVHPEDE--- 240
Query: 249 VKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEF 308
R ++ I ++ V EI + G+
Sbjct: 241 -------RYKHLIGKTVILPIVNREIPIVGD----------------------------- 264
Query: 309 KEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTEG- 367
D+V +E G+G V P H DFE+G ++ L +++ G E
Sbjct: 265 -------------DYVDMEFGSGAVKITPAHDPNDFELGNRHNLERILVMNEDGTMNENA 311
Query: 368 -KWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKV 426
+++G+ E K+++ L+E G L K + H H R + + QWF+++ +
Sbjct: 312 LQYQGMDRFECRKKLVKDLQEAGVLFKIEDHMHSVGHSERSGAVVEPYLSTQWFVRMQPL 371
Query: 427 KDKIIK--ENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIW-QSEDGEIYV 483
D I+ + +EKV + PD + + + + + DW ISRQ +WG +P W E GE+YV
Sbjct: 372 ADAAIELEKKEEKVNFVPDRFEKTYLHWMENIRDWCISRQLWWGHRIPAWYHKETGELYV 431
Query: 484 VGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDM 543
+E PE E +
Sbjct: 432 -------------------GLEAPEDSE------------------------------NW 442
Query: 544 RRVKDVVDVWFDSGIASWASLGYPR-NKELFEKLWPADFIVEGEDQVTKWFYSQQAASIV 602
+ DV+D WF S + ++++G+P E F++ +P D +V G D + W I
Sbjct: 443 EQDTDVLDTWFSSALWPFSTMGWPDVTAEDFKRYYPTDVLVTGYDIIFFWVSRMIFQGIE 502
Query: 603 AFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENL 662
P++ V +HG + DE+G KMSKSLGN + P +V+++ G D+ R+++ ++P ++L
Sbjct: 503 FTGERPFKDVLIHGLIRDEQGRKMSKSLGNGVDPMDVIDKYGADSLRYFLATGSSPGQDL 562
Query: 663 KFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLI 722
+FS++ VE N +WN A M +D L+ ++ DKWIL+R+N I
Sbjct: 563 RFSYEKVESTWNFANKIWNASRFALMNMDGMTYDELDLSGEK---SVADKWILTRLNETI 619
Query: 723 SEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFD 782
V + + + R LYNF+ +D WY+ + + L+ E E K + V D
Sbjct: 620 EHVTQLADRYEFGEVGRHLYNFIWDDFCDWYIEMAKLPLYGEDEAAKKTTRSILAY-VLD 678
Query: 783 VLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREMEFIRRIVE 842
+RLL PF P++ EEI+Q+L ES+ + WP V + D E +M+ + ++
Sbjct: 679 QTMRLLHPFMPFLTEEIWQHLPH---QGESITVSQWPAVVPEHTDTEAAADMKLLVELIR 735
Query: 843 AGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQLNAKEVKVG----RVER 898
+ R + V + I+T + + +E + N +K+G V++
Sbjct: 736 SVRNIRSEVNTPMSKQV-ELYIKTSTDEIASRLEANRSYVERFTNPSVLKIGTDIEAVDK 794
Query: 899 ELTIKPNFAKLGPEFKGDAKIIAKWINENGRELYEKGELTVEIDGKTFHLTREHIIVEEK 958
+T + A++ +G I E R E +LT E++ L E + +K
Sbjct: 795 AMTAVVSGAEVILPLEGLINI----DEEIARLQKEFDKLTKEVERVQKKLGNEGFM--KK 848
Query: 959 LPDFFVSEEFEGGRVFVDK 977
P + EE E + +V K
Sbjct: 849 APAHVIDEEREKEKDYVAK 867
>dbj|BAB06757.1| (AP001517) valyl-tRNA synthetase [Bacillus halodurans]
Length = 880
Score = 310 bits (786), Expect = 5e-83
Identities = 228/892 (25%), Positives = 405/892 (44%), Gaps = 122/892 (13%)
Query: 9 EYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDM 68
+Y P+ +E K ++W E + + + K Y + PP V+G +HLG AW+ ++D+
Sbjct: 11 KYHPQDIESKWYEYWIEGKFFEATSDETKK--PYTIVIPPPNVTGKLHLGHAWDTALQDI 68
Query: 69 IIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALN 128
+ R + MQGY+ PG D G+ + KVE L + K + +G E F++K E+
Sbjct: 69 LSRLKRMQGYDTLWLPGMDHAGIATQAKVEAKLREEGKSRYD--LGREAFVEKTWEWKEE 126
Query: 129 NLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCE 188
+ +Q+ LG+ +D+ T+ ++ + +EKGL+ + + +++W P +
Sbjct: 127 YADFIRQQWAKLGLSLDYSRERFTLDEGLSKAVREVFVKLYEKGLIYRGEYIINWDPVTK 186
Query: 189 TALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVK 248
TAL++ EV YK + ++K+P+ + + + TT P T+ + AV+ HP+
Sbjct: 187 TALSDIEVI--YKDVQGYFYHMKYPLADGDGA-IEVATTRPETMLGDTAVAVHPE----- 238
Query: 249 VKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEF 308
E Y L +V + GRE+
Sbjct: 239 -------DERYQHLIGKMVKLPI-------------TGREIP------------------ 260
Query: 309 KEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTE-- 366
++ D+V +E G+G V P H DFE+G ++ LP +++ G E
Sbjct: 261 ---------IVADDYVDMEFGSGAVKITPAHDPNDFEIGNRHNLPRILVMNEDGTMNEKA 311
Query: 367 GKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKV 426
G+++G+ E +I++ L+E+G L K E H H R + + QWF+K+ +
Sbjct: 312 GQYEGMDRFECRKQIVKDLQEQGVLFKIEEHVHSVGHSERSGAVVEPYLSTQWFVKMKPL 371
Query: 427 KDKIIK--ENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIW-QSEDGEIYV 483
++ I+ + KV + PD + + + + DW ISRQ +WG +P W E GE+YV
Sbjct: 372 AEQAIELQTTENKVNFVPDRFEKTYLRWMENIRDWCISRQLWWGHRIPAWYHKETGEVYV 431
Query: 484 VGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDM 543
+E P+D+ +
Sbjct: 432 -------------------------GHE----------APQDID--------------NW 442
Query: 544 RRVKDVVDVWFDSGIASWASLGYPRNKEL-FEKLWPADFIVEGEDQVTKWFYSQQAASIV 602
++ +DV+D WF S + ++++G+P + +++ + D +V G D + W +
Sbjct: 443 KQDEDVLDTWFSSALWPFSTMGWPDEEAPDYKRYYSTDALVTGYDIIFFWVSRMIFQGLE 502
Query: 603 AFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENL 662
P++ V +HG V D +G KMSKSLGN + P EV+++ G D RF++ ++P +L
Sbjct: 503 FTGQPPFKDVLIHGLVRDAEGQKMSKSLGNGVDPMEVIDKYGADALRFFLATGSSPGNDL 562
Query: 663 KFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLI 722
+F W+ VE N +WN A M ++D L ++ D+WIL+R+ I
Sbjct: 563 RFYWEKVESTWNFGNKIWNASRFALMNMDGMSYDEIDLTGEK---SIADQWILTRLQETI 619
Query: 723 SEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFD 782
V I+++ + R LYNF+ +DL WY+ + + L+ E E K L V D
Sbjct: 620 ETVTRLIDAYEFGEVGRHLYNFIWDDLCDWYIEMAKLPLYGEDEVAKK-TTRSVLAYVLD 678
Query: 783 VLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREMEFIRRIVE 842
+RLL P P+I EEI+Q+L ES+ + WP E+ E+ +ME ++ I+
Sbjct: 679 QTMRLLHPLMPFITEEIWQHLPH---EGESITVASWPVKSEEFTFEQAMGDMELLKDIIR 735
Query: 843 AGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQLNAKEVKVG 894
+ R + + + + I+ ++E V +ER + N + +G
Sbjct: 736 SVRNTRAELNVPMSKEI-ELHIQAKNEDVLTQLERGKHYIEKFCNPSTLVMG 786
>pir||SYBSVS valine--tRNA ligase (EC 6.1.1.9) - Bacillus stearothermophilus
Length = 880
Score = 308 bits (781), Expect = 2e-82
Identities = 237/891 (26%), Positives = 405/891 (44%), Gaps = 122/891 (13%)
Query: 9 EYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDM 68
+YD + +E ++W + + + + K + + PP V+G +HLG AW+ ++D+
Sbjct: 11 KYDHRAVEAGRYEWWLKGKFFEATGDPNKR--PFTIVIPPPNVTGKLHLGHAWDTTLQDI 68
Query: 69 IIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALN 128
I R + MQGY+V PG D G+ + KVE+ L + + +G E F+++ ++
Sbjct: 69 ITRMKRMQGYDVLWLPGMDHAGIATQAKVEEKLRQQGLSRYD--LGREKFLEETWKWKEE 126
Query: 129 NLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCE 188
+ Q+ LG+ +D+ T+ ++ + KGL+ + + +++W P +
Sbjct: 127 YAGHIRSQWAKLGLGLDYTRERFTLDEGLSKAVREVFVSLYRKGLIYRGEYIINWDPVTK 186
Query: 189 TALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVK 248
TAL++ EV YK K ++++P+ ++ + TT P T+ + AV+ HPD
Sbjct: 187 TALSDIEV--VYKEVKGALYHMRYPLADGSG-FIEVATTRPETMLGDTAVAVHPD----- 238
Query: 249 VKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEF 308
E Y K L+ K+ VK +V GRE+ I+ DEY
Sbjct: 239 -------DERY----KHLIGKM-----VKLPIV----GREIP------IIADEY------ 266
Query: 309 KEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTEG- 367
V +E G+G V P H DFE+G ++ LP +++ G E
Sbjct: 267 ---------------VDMEFGSGAVKITPAHDPNDFEIGNRHNLPRILVMNEDGTMNENA 311
Query: 368 -KWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKV 426
+++G+ E +I+ L+E+G L K E H H R + + QWF+K+ +
Sbjct: 312 MQYQGLDRFECRKQIVRDLQEQGVLFKIEEHVHSVGHSERSGAVIEPYLSTQWFVKMKPL 371
Query: 427 KDKIIK--ENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIW-QSEDGEIYV 483
+ IK + D KV + P+ + + + + + DW ISRQ +WG +P W E GEIYV
Sbjct: 372 AEAAIKLQQTDGKVQFVPERFEKTYLHWLENIRDWCISRQLWWGHRIPAWYHKETGEIYV 431
Query: 484 VGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDM 543
H P D ++
Sbjct: 432 D------------------------------------------HEPPKDI-------ENW 442
Query: 544 RRVKDVVDVWFDSGIASWASLGYP-RNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIV 602
+ DV+D WF S + ++++G+P + +++ +P D +V G D + W +
Sbjct: 443 EQDPDVLDTWFSSALWPFSTMGWPDTDSPDYKRYYPTDVLVTGYDIIFFWVSRMIFQGLE 502
Query: 603 AFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENL 662
P++ V +HG V D +G KMSKSLGN + P +V+++ G D R+++ ++P ++L
Sbjct: 503 FTGKRPFKDVLIHGLVRDAQGRKMSKSLGNGVDPMDVIDQYGADALRYFLATGSSPGQDL 562
Query: 663 KFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLI 722
+FS + VE N +WN A M ++ L+ ++ D WIL+R+N I
Sbjct: 563 RFSTEKVEATWNFANKIWNASRFALMNMGGMTYEELDLSGEK---TVADHWILTRLNETI 619
Query: 723 SEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFD 782
V E + + R LYNF+ +DL WY+ + + L+ + E K L V D
Sbjct: 620 ETVTKLAEKYEFGERGRTLYNFIWDDLCDWYIEMAKLPLYGDDEAAKK-TTRSVLAYVLD 678
Query: 783 VLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREMEFIRRIVE 842
+RLL PF P+I EEI+QNL ES+ + WP+V + +EE EM + I+
Sbjct: 679 NTMRLLHPFMPFITEEIWQNLPH---EGESITVAPWPQVRPELSNEEAAEEMRMLVDIIR 735
Query: 843 AGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQLNAKEVKV 893
A R P+ + I+T+DE V+ A+ + L N E+ +
Sbjct: 736 AVRNVRAEVNTPPSKPI-ALYIKTKDEHVRAALLKNRAYLERFCNPSELLI 785
>gb|AAK41179.1| Valyl-tRNA synthetase (valS) [Sulfolobus solfataricus]
Length = 842
Score = 308 bits (780), Expect = 3e-82
Identities = 243/900 (27%), Positives = 416/900 (46%), Gaps = 129/900 (14%)
Query: 8 REYDPKKLEEKVEKFWSENEIYRKVKELRKD---GPKYYFLDGPPYVSGAIHLGTAWNKI 64
+ Y+PK++EEK +K W E +R V R + P++ PP+ SG +H+G A+
Sbjct: 42 KHYNPKEIEEKWQKIWLSEEYWRDVFRFRDEDDKAPRFVIDTPPPFTSGELHMGHAYWVT 101
Query: 65 IKDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKE 124
I D I RF+ ++GYNV G+D GLP E+KV+ LG+ K + F++KC E
Sbjct: 102 IADTIGRFKRLEGYNVLLPQGWDTQGLPTELKVQYKLGIP-------KDNRQLFLQKCIE 154
Query: 125 FALNNLKIMTEQFKMLGIWMDWDN-PYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHW 183
+ +K M E LG +W+ Y T + +Y + +L ++ L+E + + W
Sbjct: 155 WTEEMIKKMKEAMIRLGYRPEWERFEYKTYEPKYRKIIQKSLIDMYKMNLIEMREGPVIW 214
Query: 184 CPRCETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPD 243
CP+CETALA+ EV Y ++ Y+KFP+ KE ++I TT P L A A++ +P
Sbjct: 215 CPKCETALAQSEVG--YLEKEGILAYIKFPL--KEGGEIVIATTRPELLAATQAIAVNPM 270
Query: 244 YDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYP 303
+ K ++G+I + E K ++ +
Sbjct: 271 DERYK--------------------NLVGKIALVPIFNIEVK------------IISDAD 298
Query: 304 RQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGK 363
+KEF GTG V + +D + KY LP+ +D++G+
Sbjct: 299 VEKEF--------------------GTGAVMISTYGDPQDIKWQLKYNLPIKVIVDEKGR 338
Query: 364 Y--TEGKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKY-PHCWR--CKTPLIFRATDQ 418
T G G+ +++A K+IE L+ KGYLVK +I+H H R C +P+ F Q
Sbjct: 339 IINTNGILDGLKIEQARNKMIELLKTKGYLVKVEKIKHNVLSHVERSDCLSPVEFLVKKQ 398
Query: 419 WFLKISKVKDKIIKENDEKVTWYPDWVKIRFDNGVRD-SGDWVISRQRYWGIPLPIWQSE 477
++K+ K K+++E +K+ + P + ++ ++ DW I+RQR +G PLP W E
Sbjct: 399 IYIKVLDKKQKLLEEY-KKMKFKPARMSYYLEDWIKSIEWDWNITRQRIYGTPLPFWYCE 457
Query: 478 DGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIK 537
+G L + EE L + K P P
Sbjct: 458 NGH-------------------------LVPAKEEDLPIDPIKTSPPLEKCPLC------ 486
Query: 538 VNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQ 597
G +++ V DV DVW DS + + +K +F + +PA ++G D + W +
Sbjct: 487 --GSELKPVTDVADVWIDSSVTVLYLTKFYEDKNVFNRTFPASLRLQGTDIIRTWLFYTF 544
Query: 598 AASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATN 657
+++ + VP+ V ++G VL G +MSKS GN++ P + V G D R +L A +
Sbjct: 545 FRTLMLANNVPFTTVLVNGQVLGPDGTRMSKSKGNVVSPLDRVNDFGADAIRMALLDA-S 603
Query: 658 PWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSR 717
++ F W V+ + +L LWN L +++ D K DKWIL
Sbjct: 604 IGDDFPFKWDIVKGKKMLLQKLWNASRLVYPFIAKQRLDKPK------SLHIVDKWILQE 657
Query: 718 VNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTL 777
+++ N E++ + LYN+ E ++ Y+ +I+ RL+ D +A YT+
Sbjct: 658 HKKFVTKAINAYENYDFYLVLQELYNYFWEIVADEYLEMIKHRLF-----DDDNSAKYTI 712
Query: 778 WKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREMEFI 837
++ ++ LL P P+I EEIY L F + +SV + + PKVD+ ++ ++ E I
Sbjct: 713 QRIIRDIIILLHPIAPHITEEIYSRL---FGHKKSVLLEELPKVDDIEENKRIDELGEVI 769
Query: 838 RRIVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQLNAKEVKVGRVE 897
++ + + + ++ + PV + + K+ +E +N + D + K +KV +E
Sbjct: 770 KKTNSLIRSEKIKNRLSMNTPVSVKLYAS-----KQVIELINEVKDDVM--KTLKVTNLE 822
>sp|P11931|SYV_BACST VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|143797|gb|AAA22879.1| (M16318) valyl-tRNA synthetase
[Bacillus stearothermophilus]
Length = 880
Score = 305 bits (774), Expect = 1e-81
Identities = 236/891 (26%), Positives = 404/891 (44%), Gaps = 122/891 (13%)
Query: 9 EYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDM 68
+YD + +E ++W + + + + K + + PP V+G +HLG AW+ ++D+
Sbjct: 11 KYDHRAVEAGRYEWWLKGKFFEATGDPNKR--PFTIVIPPPNVTGKLHLGHAWDTTLQDI 68
Query: 69 IIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALN 128
I R + MQGY+V PG D G+ + KVE+ L + + +G E F+++ ++
Sbjct: 69 ITRMKRMQGYDVLWLPGMDHAGIATQAKVEEKLRQQGLSRYD--LGREKFLEETWKWKEE 126
Query: 129 NLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCE 188
+ Q+ LG+ +D+ T+ ++ + KGL+ + + +++W P +
Sbjct: 127 YAGHIRSQWAKLGLGLDYTRERFTLDEGLSKAVREVFVSLYRKGLIYRGEYIINWDPVTK 186
Query: 189 TALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVK 248
TAL++ EV YK K ++++P+ ++ + TT P T+ + AV+ HPD
Sbjct: 187 TALSDIEV--VYKEVKGALYHMRYPLADGSG-FIEVATTRPETMLGDTAVAVHPD----- 238
Query: 249 VKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEF 308
E Y K L+ K+ VK +V GRE+ I+ DEY
Sbjct: 239 -------DERY----KHLIGKM-----VKLPIV----GREIP------IIADEY------ 266
Query: 309 KEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTEG- 367
V +E G+G V P H DFE+G ++ LP +++ G E
Sbjct: 267 ---------------VDMEFGSGAVKITPAHDPNDFEIGNRHNLPRILVMNEDGTMNENA 311
Query: 368 -KWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKV 426
+++G+ E +I+ L+E+G L K E H H R + + QWF+K+ +
Sbjct: 312 MQYQGLDRFECRKQIVRDLQEQGVLFKIEEHVHSVGHSERSGAVIEPYLSTQWFVKMKPL 371
Query: 427 KDKIIK--ENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIW-QSEDGEIYV 483
+ IK + D KV + P+ + + + + + W ISRQ +WG +P W E GEIYV
Sbjct: 372 AEAAIKLQQTDGKVQFVPERFEKTYLHWLENIRHWCISRQLWWGHRIPAWYHKETGEIYV 431
Query: 484 VGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDM 543
H P D ++
Sbjct: 432 D------------------------------------------HEPPKDI-------ENW 442
Query: 544 RRVKDVVDVWFDSGIASWASLGYP-RNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIV 602
+ DV+D WF S + ++++G+P + +++ +P D +V G D + W +
Sbjct: 443 EQDPDVLDTWFSSALWPFSTMGWPDTDSPDYKRYYPTDVLVTGYDIIFFWVSRMIFQGLE 502
Query: 603 AFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENL 662
P++ V +HG V D +G KMSKSLGN + P +V+++ G D R+++ ++P ++L
Sbjct: 503 FTGKRPFKDVLIHGLVRDAQGRKMSKSLGNGVDPMDVIDQYGADALRYFLATGSSPGQDL 562
Query: 663 KFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLI 722
+FS + VE N +WN A M ++ L+ ++ D WIL+R+N I
Sbjct: 563 RFSTEKVEATWNFANKIWNASRFALMNMGGMTYEELDLSGEK---TVADHWILTRLNETI 619
Query: 723 SEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFD 782
V E + + R LYNF+ +DL WY+ + + L+ + E K L V D
Sbjct: 620 ETVTKLAEKYEFGERGRTLYNFIWDDLCDWYIEMAKLPLYGDDEAAKK-TTRSVLAYVLD 678
Query: 783 VLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREMEFIRRIVE 842
+RLL PF P+I EEI+QNL ES+ + WP+V + +EE EM + I+
Sbjct: 679 NTMRLLHPFMPFITEEIWQNLPH---EGESITVAPWPQVRPELSNEEAAEEMRMLVDIIR 735
Query: 843 AGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQLNAKEVKV 893
A R P+ + I+T+DE V+ A+ + L N E+ +
Sbjct: 736 AVRNVRAEVNTPPSKPI-ALYIKTKDEHVRAALLKNRAYLERFCNPSELLI 785
>pir||T41201 isoleucyl-trna synthetase - fission yeast (Schizosaccharomyces
pombe) >gi|5701963|emb|CAB52155.1| (AL109736)
isoleucyl-trna synthetase [Schizosaccharomyces pombe]
Length = 973
Score = 302 bits (764), Expect = 2e-80
Identities = 235/824 (28%), Positives = 383/824 (45%), Gaps = 98/824 (11%)
Query: 20 EKFWSE--NEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRTMQG 77
EK++ +++Y KE + LDGPP+ +G +H+G A NKI+KD+I R++ ++G
Sbjct: 56 EKYFKSITSDLYEWQKENLNKEDSFVLLDGPPFANGRLHIGHALNKILKDIINRWQLLKG 115
Query: 78 YNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIMTEQF 137
+V PG+D HGLPIE K K E K +E K K+FA + ++ F
Sbjct: 116 RSVHYVPGWDCHGLPIESKA-------IKANAERKSSLE-IRKIAKDFANSAVQEQLMMF 167
Query: 138 KMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHEVR 197
+ + + DW + Y+T+ +++ + +K L+ + + ++W +ALAE E+
Sbjct: 168 QRMAVMGDWPSRYITMSDKFEIAELKVFLSLLQKDLIFRQNKPVYWSSSSRSALAESEIE 227
Query: 198 GEYKLRKDPSIYVKFPV-----EGKE--NEYLLIWTTTPWTLPANLAVSAHPDYDYVKVK 250
+ SIY FPV +G E N L+WTTTPWT+P+NLA+S HP+ +Y
Sbjct: 228 YDDN-HVSTSIYFTFPVNSFSIDGCEYNNVKALVWTTTPWTIPSNLALSYHPEINYGL-- 284
Query: 251 VEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFKE 310
+ ++++ LV + G K + + Y + L+ P+Q
Sbjct: 285 --YQHNNSIYLMSDNLVPNLDFMQGAKR--LASCPSDIISSFTYENPLL---PKQ----- 332
Query: 311 KYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYT----E 366
+ + +++VT + GTG+VH APGHG ED+ +G + L +SPLDD G+YT +
Sbjct: 333 ----SFPFLQSNYVTNDIGTGIVHVAPGHGMEDYLLGLENNLRPFSPLDDYGRYTKEALD 388
Query: 367 GKWKGIYV-KEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISK 425
G +G+ V + K+I ++ + +VK +H+YP+ WR PLI RAT QWF+ +
Sbjct: 389 GSLEGLEVLGDGGKKVISIMKNQNMIVKVSPYKHRYPYDWRTHKPLILRATPQWFISLEN 448
Query: 426 VKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVG 485
+ IK D V P + R + +W ISRQR WG+P+P+ +Y G
Sbjct: 449 ERKTAIKALD-SVKMIPPNSRARLLGFLNGRPEWCISRQRAWGLPIPV-------LYEKG 500
Query: 486 SWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRR 545
+ L+ + ++ E++E+ E + E + +H Y K+ R
Sbjct: 501 TKIPLLTVK-SVSYIIEKMEV-EGVDSWFNDTENNGHAQWVHPDY--------RNKEYIR 550
Query: 546 VKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVAFD 605
+ +DVWFDSG SW ++ +NK L D +EG DQ WF S + A+
Sbjct: 551 GTETLDVWFDSG-TSWTTIAPRKNKPLI------DLCLEGSDQHRGWFQS-LLLTYTAYQ 602
Query: 606 T---VPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERA---------GRDTFRFYML 653
+ P+ + HG++ DE+G K SKSLGN+ PE+V+ G D R L
Sbjct: 603 SKPEAPFSTLFTHGFIFDERGQKQSKSLGNVTDPEDVINGKLLKGKKLPYGVDLLR---L 659
Query: 654 WATNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNP-------DELP 706
W S NIL V + F L+ D
Sbjct: 660 WVA--------SCDSTNDTNLGPNILTQVGESLKKWRLTSRFCLGNLHDWNTSSSVDVGE 711
Query: 707 FREEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVE-G 765
R DK L +++ +E+ ES+ + K L F+ LS Y ++ RL+ +
Sbjct: 712 LRGIDKLALVQLDKFQTEIRELYESYSINKVVHHLNYFMNSFLSSTYFDAVKDRLYADLP 771
Query: 766 EDPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTN 809
+ + L+ L+ ++P TP +A+EI+Q+L + N
Sbjct: 772 NSVSRRSVQTVLYHSLLTLIWAISPITPLLAQEIWQSLPDSYLN 815
>sp|P96142|SYV_THETH VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|1814011|emb|CAA71837.1| (Y10900) valyl-tRNA
synthetase [Thermus thermophilus]
Length = 854
Score = 298 bits (755), Expect = 2e-79
Identities = 244/890 (27%), Positives = 402/890 (44%), Gaps = 143/890 (16%)
Query: 8 REYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKD 67
+ YDPK +E K + W++N K + P + PP V+G++H+G A + ++D
Sbjct: 5 KAYDPKSVEPKWAEKWAKNPFVANPKSGK---PPFVIFMPPPNVTGSLHMGHALDNSLQD 61
Query: 68 MIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFAL 127
+IR++ M+G+ PG D G+ +V VE+ L LK K + +G E F+++ ++
Sbjct: 62 ALIRYKRMRGFEAVWLPGTDHAGIATQVVVERLL-LKEGKTRHD-LGREKFLERVWQWKE 119
Query: 128 NNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRC 187
+ + +Q K LG DW T+ +E + + R + +GL + R+++WCPRC
Sbjct: 120 ESGGTILKQLKRLGASADWSREAFTM-DENAPAVPYAFSRYYHEGLAYRAPRLVNWCPRC 178
Query: 188 ETALAEHEVRGEYKLRKDPSIY-VKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDY 246
ET L++ EV E K +Y +++ VEG ++ I T P T+ A+ A++ HP
Sbjct: 179 ETTLSDLEVETEPTPGK---LYTLRYEVEG--GGFIEIATVRPETVFADQAIAVHP---- 229
Query: 247 VKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQK 306
E RY H+L
Sbjct: 230 -------------------------------------------EDERYRHLLGKR----- 241
Query: 307 EFKEKYEWAHRVILAD-FVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYT 365
A ILAD V + GTG + P H D+E+G+++GL S ++ +G+
Sbjct: 242 --------ARIPILADPAVEKDFGTGALKVTPAHDPLDYEIGERHGLKPVSVINLEGRM- 292
Query: 366 EGK-----WKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWF 420
EG+ +G+ EA K +E RE G+LVK + C RC TP+ + QW+
Sbjct: 293 EGERVPEALRGLDRFEARRKAVELFREAGHLVKEEDYTIALATCSRCGTPIEYAIFPQWW 352
Query: 421 LKISKVKDKIIKE-NDEKVTWYPD-WVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSED 478
L++ + ++++K + + P+ W K+ D + + DW ISRQ +WG +P W ED
Sbjct: 353 LRMRPLAEEVLKGLRRGDIAFVPERWKKVNMD-WLENVKDWNISRQLWWGHQIPAWYCED 411
Query: 479 GEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKV 538
+ VN R PE Y E E P
Sbjct: 412 CQA-----------------VNVPR---PERYLEDPTSCEACGSPR-------------- 437
Query: 539 NGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQA 598
++R +DV D WF S + ++LG+P E + +P D +V G D + W +
Sbjct: 438 ----LKRDEDVFDTWFSSALWPLSTLGWPEETEDLKAFYPGDVLVTGYDILFLWVSRMEV 493
Query: 599 ASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNP 658
+ P++ V +HG VLDEKG KMSKS GN+I P E+VER G D RF +++
Sbjct: 494 SGYHFMGERPFKTVLLHGLVLDEKGQKMSKSKGNVIDPLEMVERYGADALRFALIYLATG 553
Query: 659 WENLKFSWKGVEQVRRMLNILWNV--YVLASTYMSLDNFDPRKLNPDELPFREEDKWILS 716
++++ + +E R N L+N +VL +S + F ++ P D+++ +
Sbjct: 554 GQDIRLDLRWLEMARNFANKLYNAARFVL----LSREGFQAKEDTP-----TLADRFMRT 604
Query: 717 RVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYT 776
R++ + E+ E+ L +A R +Y V + WY+ + L T
Sbjct: 605 RLSRGVEEITALYEALDLAQAAREVYELVWSEFCDWYLEAAKPAL-----KAGNAHTLRT 659
Query: 777 LWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREMEF 836
L +V VLL+LL P P++ E+YQ L T E + + WP+ + DEE ER E
Sbjct: 660 LEEVLAVLLKLLHPMMPFLTSELYQAL----TGKEELALEAWPEPGGR--DEEAERAFEA 713
Query: 837 IRRIVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQL 886
+++ V A A + A + V R+ +E E V++ +E + R L
Sbjct: 714 LKQAVTAVRALKAEAGLPPAQEV-RVYLEGETAPVEENLEVFRFLSRADL 762
>sp|P56000|SYV_HELPY VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|7437645|pir||A64664 valine--tRNA ligase (EC 6.1.1.9)
- Helicobacter pylori (strain 26695)
>gi|2314306|gb|AAD08195.1| (AE000621) valyl-tRNA
synthetase (valS) [Helicobacter pylori 26695]
Length = 874
Score = 293 bits (743), Expect = 6e-78
Identities = 234/899 (26%), Positives = 417/899 (46%), Gaps = 149/899 (16%)
Query: 1 MIKEPEFREYDPKKLEEKVEKFWSENEIYR--KVKELRKDGPKYYFLDGPPYVSGAIHLG 58
MI + E Y P+++E+K+ + S + + +++ ++ + PP V+G +H+G
Sbjct: 1 MIMKQEPTTYQPEEIEKKIYEICSHRGYFEIDGNEAIQEKNKRFCLMMPPPNVTGVLHIG 60
Query: 59 TAWNKIIKDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQAL---GLKTKKEIEEKIGV 115
A ++D++ R++ M GY QPG D G+ + VE+ L G+K +E +G
Sbjct: 61 HALTLSLQDILARYKRMDGYKTLYQPGLDHAGIATQNVVEKQLLSQGIK-----KEDLGR 115
Query: 116 ENFIKKCKEFALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLE 175
E FIKK E+ + + EQ K LG+ + T+ + + +EKGL+
Sbjct: 116 EEFIKKVWEWKEKSGGAILEQMKRLGVSAAFSRTRFTMDKGLQRAVKLAFLKWYEKGLII 175
Query: 176 KDKRVLHWCPRCETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPAN 235
+D +++WC + + AL++ EV EY+ RK Y+++ +E ++ +YL++ TT P TL +
Sbjct: 176 QDNYMVNWCTK-DGALSDIEV--EYEERKGALYYIRYYLENQK-DYLVVATTRPETLFGD 231
Query: 236 LAVSAHPDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYV 295
A+ +P+ + R ++ + KA++ + R +
Sbjct: 232 SALMVNPNDE----------RYKHLVGQKAILPLIH---------------------RTI 260
Query: 296 HILMDEYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVY 355
I+ DE+ V +E GTG V PGH D+EVG+++ L
Sbjct: 261 PIIADEH---------------------VEMEFGTGCVKVTPGHDFNDYEVGKRHHLETI 299
Query: 356 SPLDDQGKYTE--GKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIF 413
D++G G+++ + EA K++E L+E L K E H+ HC+RC +
Sbjct: 300 KIFDEKGILNAHCGEFENLERLEARDKVVERLKENALLEKIEEHTHQVGHCYRCHNVVEP 359
Query: 414 RATDQWFLKISKVKDKIIKENDEKVTWYP-DWVKIRFDNGVRDSGDWVISRQRYWGIPLP 472
+ QWF+K + I K +YP +W+ ++ +R+ W ISRQ +WG +P
Sbjct: 360 YVSKQWFVKPEIAQSSIEKIQQGLARFYPSNWIN-NYNAWMRELRPWCISRQLFWGHQIP 418
Query: 473 IWQSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVD 532
++ E+ +V ++ P S
Sbjct: 419 VFTCENNHQFV-------------------SLDTPLSCPT-------------------- 439
Query: 533 AFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKE-LFEK-----LWPADFIVEGE 586
+ + + KDV+D WF SG+ ++++LG+ + K LF + +P ++ G
Sbjct: 440 -----CKSETLEQDKDVLDTWFSSGLWAFSTLGWGQEKSGLFNESDLKDFYPNTTLITGF 494
Query: 587 DQVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRD 646
D + W S +P++ + +H V DEKG+KMSKS GN+I P E++E+ G D
Sbjct: 495 DILFFWVARMLFCSESLLGELPFKDIYLHALVRDEKGEKMSKSKGNVIDPLEMIEKYGAD 554
Query: 647 TFRFYMLWATNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSL--DNF-DPRKLNPD 703
+ RF + ++K S +E + N L+N A++Y+ L ++F D +LN
Sbjct: 555 SLRFTLANLCATGRDIKLSTTHLENNKNFANKLFN----AASYLKLKQESFKDKERLNEY 610
Query: 704 ELPFREEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWV 763
+ P ++ SR+NS E N ++++ AT LY F+ + W++ + V
Sbjct: 611 QTPL---GRYAKSRLNSATKEARNALDNYRFNDATTLLYRFLWGEFCDWFIEFSK----V 663
Query: 764 EGEDPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIR-PFTNVESVHMLDWPKVD 822
E E D+L + V L+LL PF P+I+E +Y L N ES+ ++ +PK
Sbjct: 664 ENEAIDELGS------VLKEALKLLHPFMPFISESLYHKLSNTELENTESIMVMPYPK-- 715
Query: 823 EKAIDEELEREMEFIRRIVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRI 881
+ A DE+LE E E I+ + + +R KI L P I+++ +++A+E R+
Sbjct: 716 DLAQDEKLEHEFEVIKDCI----VSLRRLKIMLETP--PIVLKEASVGLREAIENTERL 768
>pir||T19442 hypothetical protein C25A1.7a - Caenorhabditis elegans
>gi|3874441|emb|CAB02766.1| (Z81038) predicted using
Genefinder~Similarity to Yeast isoleucyl-tRNA synthetase
(SW:P48526), contains similarity to Pfam domain: PF00133
(tRNA synthetases class I (I, L, M and V)), Score=424.2,
E-value=3.8e-124, N=1~cDNA EST yk408e2.3 comes from
this>
Length = 1131
Score = 291 bits (738), Expect = 2e-77
Identities = 228/850 (26%), Positives = 393/850 (45%), Gaps = 81/850 (9%)
Query: 26 NEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRTMQGYNVWRQPG 85
N++Y K RKD + LDGPPY +G H G A NKI+KD +++ R GY V +PG
Sbjct: 161 NDLYSWQKAARKDSEIFELLDGPPYANGEAHTGHAINKILKDFVVKSRIALGYRVLFRPG 220
Query: 86 YDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIMTEQFKMLGIWMD 145
+D HGLPIE+K+ + G + E + A + F+ G+ D
Sbjct: 221 WDCHGLPIELKIGKQQGNAGSRTPLETRAAARIV------ADEAIGKQMNAFRRWGVTAD 274
Query: 146 WDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHEVRGEYKLRKD 205
W+ PY+T Y+ + + E+ L+ + + ++W P TALAE E+ K +
Sbjct: 275 WEKPYVTKSPSYVAAQLDIFAKLVEQKLVYRSFKPVYWSPSSNTALAESELEYNDK-HQS 333
Query: 206 PSIYVKFPVEGKENE---------------YLLIWTTTPWTLPANLAVSAHPDYDYVKVK 250
S Y +F + + + LIWTTTPWTLP N A+S Y ++
Sbjct: 334 TSAYFRFKLINFSSSDVIWAHSEPSKISQFFALIWTTTPWTLPLNNAISVSSAIQYSLIQ 393
Query: 251 VE---FNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKE 307
+ N ++++A L+++ K +VV K L G RY +E
Sbjct: 394 FDNEINNPTSTFYVIASKLLEEFQKSSDRKCKVVGTVKPANLIGRRYKSCWHNELG---- 449
Query: 308 FKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTEG 367
YE H VT GTGLVHTA HG +D++V G V S +D +G YT
Sbjct: 450 -LPIYEGPH-------VTDTVGTGLVHTAFAHGFQDYDVAISKGDRVESFVDSRGCYTRH 501
Query: 368 KWKGIYVKEA---DPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKIS 424
+ KE KI L +V + H YP+ WR K P+I R+++QWF+ +
Sbjct: 502 LGHDLDGKEVLGEGQKIALRLLNHD-IVHVSKHVHSYPYDWRTKKPVIIRSSEQWFIDVD 560
Query: 425 KV-KDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYV 483
++ K + +D V ++ V W ISRQR WG P+P ++G Y
Sbjct: 561 EIGKRASMMLDDISVAAGDSDLRASLKQLVTTRKSWCISRQRVWGTPIPALVDDNGGSY- 619
Query: 484 VGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPY-VDAFIIKVNGKD 542
+ R+L+E + E ++ + ++E L E++ R + + I+
Sbjct: 620 --TSRKLIEWVAKLTRERENTDVWWEID-----VKEILENEEVRRSLEIPSDIV----SQ 668
Query: 543 MRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIV 602
+++ D++DVW DSG+A A+ R+ + E+ AD ++EG DQ WF S S+
Sbjct: 669 LKKNTDIMDVWLDSGLAWHAA----RDNDT-EREHVADVVLEGVDQFRGWFQSLLLTSVA 723
Query: 603 AFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERA------GRDTFRFYMLWAT 656
+ +PY+++ +HG+ +DE +KMSKS+GN++ P + + + G D RF++ A
Sbjct: 724 VQNKLPYKKIIVHGFCIDENNNKMSKSIGNVVDPTMLTDGSLKQKAIGADGLRFWV--AL 781
Query: 657 NPWENL---KFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKW 713
+ EN K K ++ V + + N + FD +++ + P + D
Sbjct: 782 SGSENAGESKIGMKIIDDVDKKVIAFRNGF--RFMIGGCQGFDGKQV---KFPLKTLDID 836
Query: 714 ILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDK-LA 772
+L ++++ F L F+ + S YV+ +R RL+ + + ++
Sbjct: 837 MLQNCDAIVKRSIVNYNDFKFRTVANDLTQFLQRNFSANYVKYVRDRLYCDKVGSESHIS 896
Query: 773 AYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAI--DEEL 830
A +TL ++ L +++P P+++ E+ Q+L P ++ + + L + + + ++L
Sbjct: 897 AQFTLHRLAHNLAHIISPILPHLSSEVLQHL--PGSHEKQILRLKFEDLHYGLLTPHDQL 954
Query: 831 EREMEFIRRI 840
+ M+F+ +
Sbjct: 955 SKHMKFVYEV 964
>sp|P36420|SYV_LACCA VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|541449|pir||A49856 valine--tRNA ligase (EC 6.1.1.9)
- Lactobacillus casei >gi|409360|gb|AAA57558.1| (L08854)
valyl-tRNA synthetase [Lactobacillus casei]
Length = 901
Score = 290 bits (735), Expect = 5e-77
Identities = 250/998 (25%), Positives = 434/998 (43%), Gaps = 143/998 (14%)
Query: 9 EYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDM 68
+YD K +EE + W + ++++ + K Y + PP V+G +H+G AW+ ++D+
Sbjct: 30 KYDHKAVEEGRYQEWLDEDVFKPSGD--KKAKPYSIVIPPPNVTGKLHMGHAWDTTLQDI 87
Query: 69 IIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALN 128
+IR + ++G++ PG D G+ + KVE L + + +G E F++K E+
Sbjct: 88 VIRQKRIEGFDTLWLPGMDHAGIATQAKVEAKLRKEGISRYD--LGREKFVQKVWEWKDE 145
Query: 129 NLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCE 188
K + Q+ +G+ +D+ T+ ++ + +GL+ + + +++W P+
Sbjct: 146 FAKTIHGQWAKMGLSLDYSRERFTLDKGLNQAVRRVFVDLYNQGLIYRGEYIVNWDPQAR 205
Query: 189 TALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVK 248
TAL++ EV +K K +VK+P Y+ I TT P T+ + AV+ HP + K
Sbjct: 206 TALSDIEVI--HKDDKGAFYHVKYPFADGSG-YIEIATTRPETMMGDTAVAVHPGDERYK 262
Query: 249 VKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEF 308
V G E LA R + I+ D Y
Sbjct: 263 DMV---GTELILPLAN----------------------------RKIPIIEDAY------ 285
Query: 309 KEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTE-- 366
V E GTG V P H DF+VG ++ L + ++D G E
Sbjct: 286 ---------------VDPEFGTGAVKITPAHDPNDFQVGNRHDLKRINTMNDDGTMNENA 330
Query: 367 GKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKV 426
GK++G+ EA ++ L + G L+K I H H R + R + QWF+K+ +
Sbjct: 331 GKYQGMDRFEARKAMVADLDKAGLLLKVEPIVHSVGHSERTGVQVEARLSTQWFVKMKPL 390
Query: 427 KDKIIK---ENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSED-GEIY 482
+ IK E D+KVT+ P+ + + + + DWVISRQ +WG +P W ++ GE Y
Sbjct: 391 AEAAIKAQQEPDKKVTFVPERFEHTYLQWMENIHDWVISRQLWWGHQIPAWYNKQTGETY 450
Query: 483 VVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKD 542
V +E P+ E +
Sbjct: 451 V-------------------GMEAPKDIE------------------------------N 461
Query: 543 MRRVKDVVDVWFDSGIASWASLGYPRNKEL-FEKLWPADFIVEGEDQVTKWFYSQQAASI 601
++ DV+D WF S + ++++G+P +++ +P D +V G D + W +
Sbjct: 462 WKQDPDVLDTWFSSALWPFSTMGWPNTDAPDYKRYYPTDTLVTGYDIIPFWVARMIFQGL 521
Query: 602 VAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWEN 661
P++ +HG + DE+G KMSKSLGN I P +V+E+ G D R++++ P ++
Sbjct: 522 HFTHQRPFQYTLIHGLMRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLITGNKPGQD 581
Query: 662 LKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSL 721
+FS+K VE +N +WN + M+L + D + PD F DKW+ +++N
Sbjct: 582 TRFSYKQVEAAWNFINKIWN--ISRFVMMNLGDLDTPQ-QPDPSTFDLSDKWLFAQLNET 638
Query: 722 ISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVF 781
I +V + F + R LYNF L+ WYV + ++ L+ + E K A L
Sbjct: 639 IKQVMDLSARFEFGEMGRTLYNFTWNVLADWYVEMSKEVLYGDDEQA-KAAKRVNLAYAL 697
Query: 782 DVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREMEFIRRIV 841
D +LRLL P P++ +++ L P T +S+ +P + + + M+ I ++
Sbjct: 698 DQILRLLHPVMPFVHGKLW--LALPHTG-KSIVTASYPVANTAFENADATSAMDAIIALI 754
Query: 842 EAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQLNAKEVKVGRVERELT 901
R+ A L+ V I+++ D +K E+ + +N+K VG E
Sbjct: 755 RGVRGIRKEAGAPLKTKV-DILVKLTDPALKPIFEQNFDFIDRFVNSKAFTVGTDVAE-- 811
Query: 902 IKPNFAKLGPEFKGDAKIIAKWINENGRELYEKGELTVEIDGKTFHLTREHIIVEEKL-- 959
P+ G A I I EL + E ++ L +E +++KL
Sbjct: 812 ---------PKMAGSAVITGATIFVPLNELIDLDEEKAKLTKDAKKLEQEIARIDKKLNN 862
Query: 960 -------PDFFVSEEFEGGRVFVDKTLTRELIAEGLAR 990
P+ V+E+ F D+ + + E L R
Sbjct: 863 QGFLSKAPEAVVAEQRTKRSDFEDQLTSTKQRLEQLQR 900
>emb|CAC11189.1| (AL445063) valyl-tRNA synthetase related protein [Thermoplasma
acidophilum]
Length = 791
Score = 286 bits (725), Expect = 7e-76
Identities = 237/885 (26%), Positives = 406/885 (45%), Gaps = 123/885 (13%)
Query: 9 EYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPP-YVSGAIHLGTAWNKIIKD 67
+ D ++EEK ++W E ++YR D K + +D PP VSG +H+G +++ D
Sbjct: 2 DIDVNQMEEKWIRYWDEKDVYRFEPA---DRDKVFAIDTPPPTVSGKMHMGHSFSYPHID 58
Query: 68 MIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFAL 127
I R++ M+GY+V+ G+D +GLP E VE+ G+K VE FI+ CKE +
Sbjct: 59 FIARYKRMRGYHVFFPWGFDDNGLPTERYVEKETGIKPSDS-----NVEEFIRLCKEISE 113
Query: 128 NNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRC 187
++ K + E +K +G+ + + Y+T E I + KG + +D CP C
Sbjct: 114 SSEKSLLEGWKRIGMSCYFKDYYVTSSPESIRISQSMFLDLVRKGRVYRDLAPSIRCPTC 173
Query: 188 ETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYV 247
+T++++ E++ + K +Y+ F V + L I TT P L + +AV +P
Sbjct: 174 KTSISQIEMKDQEMHTK--LVYINFSVGDRP---LTIATTRPEMLGSCVAVFVNP----- 223
Query: 248 KVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKE 307
++ + R+L G KE
Sbjct: 224 ----------------------------------DDARYRDLIG--------------KE 235
Query: 308 FKEKYEWAHRVILADF-VTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTE 366
H I+AD V + GTG + D ++ +KY LP+ +D G+ TE
Sbjct: 236 ATVPIFGNHVRIMADASVDMNFGTGAEMVCTFGDQNDLDLWKKYNLPLKISIDKDGRMTE 295
Query: 367 --GKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKIS 424
G KG+ + +A KI+E LRE G++VK I+H RC TP+ QWF+K
Sbjct: 296 EAGPLKGLSISDARKKIVEILREGGHVVKEESIKHSVNTHERCGTPIEIFIEKQWFIKYL 355
Query: 425 KVKDKIIKENDEKVTWYPDWVKIRFDNGVRD-SGDWVISRQRYWGIPLPIWQSEDGEIYV 483
+KD I EN K+ W P+++++R++N V DW+ISRQRY+G+P P+W D V
Sbjct: 356 DLKDAFI-ENGRKIEWTPEYMRVRYENWVNGLKWDWLISRQRYYGVPFPVWYCADCGNTV 414
Query: 484 VGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDM 543
EL RI+ P ++ L PE
Sbjct: 415 YADESELPV--------DPRIQKPSKKCDRCG--STNLVPE------------------- 445
Query: 544 RRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVA 603
+DV+D W S + +L + LF+K +P D +G D ++ W ++ A S +
Sbjct: 446 ---RDVMDTWATSSLTPRIAL---THFGLFDKYYPEDLRGQGHDIISFWAFTTIARSKIH 499
Query: 604 FDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWAT--NPWEN 661
D +P+ R+ + G V D G+KMSKS GNI+ ++++ G D RF WA+ + ++
Sbjct: 500 DDRIPWFRIMISGNVYDMYGEKMSKSKGNIVDIYSMIDKYGADALRF---WASTVSQGDD 556
Query: 662 LKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSL 721
++ + + RR + ++N L RK+ E ++WIL+ + +
Sbjct: 557 IRIKDQDFTRGRRTVIKMYNAKKLIDILKG-----DRKIRLFEDVKHPVNRWILTEDSRI 611
Query: 722 ISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIR---KRLWVEGEDPDKLAAYYTLW 778
+ + ++++ ++KA AL F Y+ +I+ ++ G+ YT
Sbjct: 612 METITTHMDNYEVSKARTALDTFFWNVFCDNYLEMIKPIIQKASAAGDYDTVDETVYTAS 671
Query: 779 KVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREMEFIR 838
KV + + AP P+IAEEIYQ + P + S+H+ WP DEK + E+ +I
Sbjct: 672 KVMLDVAKAYAPIMPFIAEEIYQTIDFPGRKI-SIHVDSWP--DEKRRYSDANEEVSYIV 728
Query: 839 RIVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILR 883
+++A +A+ AK+ + V+ ++ + ++K + L+ +LR
Sbjct: 729 SVIDAIRSAKSAAKVSVGTRVKVASVKGRKDLIEKYRDLLSGMLR 773
>pir||G83167 valyl-tRNA synthetase PA3834 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9950009|gb|AAG07221.1|AE004800_10
(AE004800) valyl-tRNA synthetase [Pseudomonas
aeruginosa]
Length = 950
Score = 283 bits (717), Expect = 6e-75
Identities = 236/908 (25%), Positives = 389/908 (41%), Gaps = 181/908 (19%)
Query: 8 REYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKD 67
+ Y P +E + W N+ + E G Y + PP V+G++H+G +N I D
Sbjct: 3 KTYQPHAIETSWYETWESNDYFAPSGE----GQPYTIMIPPPNVTGSLHMGHGFNNAIMD 58
Query: 68 MIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFAL 127
+IR+R MQG N QPG D G+ ++ VE+ LG + +G E F++K E+
Sbjct: 59 ALIRYRRMQGRNTLWQPGTDHAGIATQMVVERQLGAQGVS--RHDLGREKFLEKVWEWKE 116
Query: 128 NNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRC 187
+ +T Q + LG +DW T+ + E+ R E GL+ + KR+++W +
Sbjct: 117 QSGGNITRQIRRLGSSVDWSRERFTMDDGLSEAVKEAFVRLHEDGLIYRGKRLVNWDTKL 176
Query: 188 ETALAEHEVRGEYKLRKDPSIYVKFP-VEGKEN----EYLLIWTTTPWTLPANLAVSAHP 242
TA+++ EV E K ++++P V G + +YL++ TT P TL + AV+ HP
Sbjct: 177 HTAISDLEV--ENHDEKGHLWHLRYPLVNGAKTSEGLDYLVVATTRPETLLGDAAVAVHP 234
Query: 243 -DYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDE 301
D Y K+ +F E+ + G R++ I+ DE
Sbjct: 235 EDERYAKLIGQF------------------AELPIVG--------------RHIPIIADE 262
Query: 302 YPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDD- 360
Y V E GTG V P H D+EVG+++ LP+ + D
Sbjct: 263 Y---------------------VDREFGTGCVKITPAHDFNDYEVGKRHDLPLINIFDKN 301
Query: 361 -------QGKYTEG------------KWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKY 401
Q + +G + G+ A I+ G L K + K
Sbjct: 302 AAVLAQAQVFHLDGSVNPNLDPSLPQSYAGMDRFAARKAIVAEFEAMGLLEKVDDHALKV 361
Query: 402 PHCWRCKTPLIFRATDQWFLKISKV-KDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWV 460
P R T + TDQW++ + +D I D ++ + P + + + +RD DW
Sbjct: 362 PKGDRSGTVIEPWLTDQWYVSTKPLAEDAIAAVEDGRIQFVPKQYENMYFSWMRDIQDWC 421
Query: 461 ISRQRYWGIPLPIWQSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEK 520
ISRQ +WG +P W E G +YV R+ VE+ + K
Sbjct: 422 ISRQLWWGHRIPAWYDEAGNVYV---GRDEVEVRT----------------------KHK 456
Query: 521 LGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPAD 580
LG N ++R+ +DV+D WF SG+ ++++LG+P+ E + P D
Sbjct: 457 LG----------------NEAELRQDEDVLDTWFSSGLWTFSTLGWPQQTEFLKTFHPTD 500
Query: 581 FIVEGEDQVTKWFYSQQAASIVAFDT------VPYRRVAMHGYVLDEKGDKMSKSLGNII 634
+V G D + W ++ +P++ V +HG V D +G KMSKS GN++
Sbjct: 501 VLVTGFDIIFFWVARMIMLTMHLVKNPDGTPQIPFKTVYVHGLVRDGQGQKMSKSKGNVL 560
Query: 635 RPEEVVE----------------------------RA---------GRDTFRFYMLWATN 657
P ++V+ RA G D RF +
Sbjct: 561 DPLDIVDGIDLDTLLQKRTSGMMQPKLAEKIAKQTRAEFPEGIASYGTDALRFTFCSLAS 620
Query: 658 PWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRK--LNPDELPFREEDKWIL 715
++KF VE R N +WN A+ ++ ++N D + +N + + D+WI+
Sbjct: 621 TGRDIKFDMGRVEGFRNFCNKIWN----AANFV-IENTDGQDTGVNGEPVELSSVDRWII 675
Query: 716 SRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDK-LAAY 774
S++ EV +++F A +ALY F+ ++ WY+ L++ LW E ++
Sbjct: 676 SQLQRTEQEVTRQLDAFRFDLAAQALYEFIWDEYCAWYLELVKPVLWDENAPIERQRGTR 735
Query: 775 YTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLD-WPKVDEKAIDEELERE 833
TL +V + LRL PF P+I EEI+Q + ML WP DE ID E +
Sbjct: 736 RTLIRVLETALRLAHPFMPFITEEIWQRIKGQAGKEGPTLMLQPWPVADEGRIDAAAEGD 795
Query: 834 MEFIRRIV 841
+E+++ ++
Sbjct: 796 IEWVKALM 803
>sp|Q55522|SYV_SYNY3 VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|7437643|pir||S76034 hypothetical protein -
Synechocystis sp. (strain PCC 6803)
>gi|1001391|dbj|BAA10881.1| (D64006) valyl-tRNA
synthetase [Synechocystis sp.]
Length = 910
Score = 280 bits (708), Expect = 7e-74
Identities = 229/913 (25%), Positives = 403/913 (44%), Gaps = 133/913 (14%)
Query: 9 EYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDM 68
+Y+P E K + W E+ ++ + + G Y + PP V+G++H+G A+ + D
Sbjct: 8 QYEPTVTEAKWQTAWEESHAFKADPD--RPGEPYCVVIPPPNVTGSLHMGHAFESSLIDT 65
Query: 69 IIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALN 128
++R+ M+G N PG D + ++ +E+ L K + + + +G E F+++ ++
Sbjct: 66 LVRYHRMRGDNTLWLPGTDHASIAVQTILERQL--KAEGKTRDDLGREKFLERAWQWKAE 123
Query: 129 NLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCE 188
+ + Q + LG+ +DW T+ ++ + +E+GL+ + +++WCP +
Sbjct: 124 SGSTIVNQLRRLGVSVDWTRERFTMDEGLSQAVKTAFIKLYEEGLIYRGNYLVNWCPASQ 183
Query: 189 TALAEHEVRGEYKLRKDPSI-YVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYV 247
+A+++ EV + D + Y ++P+ E L++ TT P T+ + V+
Sbjct: 184 SAVSDLEVENQ---EVDGHLWYFRYPLTDGSGE-LVVATTRPETMLGDTGVAV------- 232
Query: 248 KVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKE 307
N +E + A+V K + V E+
Sbjct: 233 ------NPHDERYA---AMVGKTITLPLVNREIP-------------------------- 257
Query: 308 FKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTE- 366
++ + V E GTG V P H DF +GQ++ LP + L+ G E
Sbjct: 258 ----------IVADELVDPEFGTGCVKVTPAHDPNDFVMGQRHNLPFINLLNKDGSLNEN 307
Query: 367 -GKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISK 425
G + G EA +++ L +G+LVK H P+ R K P+ + QWF+KI
Sbjct: 308 GGDFAGQDRFEARKNVVQALEAQGFLVKIEPYRHSVPYGDRGKVPVEPLLSTQWFVKIES 367
Query: 426 VKDKIIKENDEKVTWYPDWVKIRFDNGVRD----SGDWVISRQRYWGIPLPIWQSEDGEI 481
+ + DE + P++V R+ RD DW ISRQ +WG +P W
Sbjct: 368 LAQNALACLDEDNS--PNFVPERWGKVYRDWLVKLKDWCISRQLWWGHQIPAW------- 418
Query: 482 YVVGSWRELVELAVAIEVNG---ERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKV 538
YV+ E NG + +Y+E + + K + P V
Sbjct: 419 YVIS------------ETNGAITDHTPFIVAYDEAEALAKAKAE----YGPTVQ------ 456
Query: 539 NGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQA 598
+++ DV+D WF SG+ ++++G+P + K +P +V G D + W
Sbjct: 457 ----LQQDPDVLDTWFSSGLWPFSTMGWPEQTDDLAKYYPTSTLVTGFDIIFFWVARMTM 512
Query: 599 ASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATN- 657
+ +P++ V +HG V DE G KMSKS N I P ++ + G D R+ ++
Sbjct: 513 MAGHFTGQIPFKDVYIHGLVRDENGKKMSKSANNGIDPLLLINKYGTDALRYTLIREVAG 572
Query: 658 -------PWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLN--PDELPFR 708
++ K + VE R N LWN M+LD P++L P E
Sbjct: 573 AGQDISLQYDRQKDESESVEASRNFANKLWNA--ARFVMMNLDGQTPQQLGLAPGE-DLE 629
Query: 709 EEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLW-VEGED 767
D+WILSR+N +I + IE + L +A + LY F+ D WY+ L + RLW EG D
Sbjct: 630 LADRWILSRLNQVIQQTREQIEDYGLGEAAKGLYEFIWGDFCDWYIELAKPRLWNKEGGD 689
Query: 768 ---PDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEK 824
+L A L D +++LL PF P+I EE++Q L + + + + +P V++
Sbjct: 690 VGTQRQLVARQVLAHTLDSIIKLLHPFMPHITEELWQTLHQ--AEGQFLALQAYPTVNQS 747
Query: 825 AIDEELEREMEFIRRIVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRD 884
+D LE + + + R A IK V +I+++E++ ++ ++ +RD
Sbjct: 748 LVDPALETQFALLIETLRTIRNLRAEAGIKPGAMV-TVILQSENDQERQTLQLGETYIRD 806
Query: 885 QLNAKEVKVGRVE 897
+G+VE
Sbjct: 807 --------IGKVE 811
>sp|P43834|SYV_HAEIN VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|1075441|pir||G64121 valine--tRNA ligase (EC 6.1.1.9)
- Haemophilus influenzae (strain Rd KW20)
>gi|1574225|gb|AAC23038.1| (U32819) valyl-tRNA
synthetase (valS) [Haemophilus influenzae Rd]
Length = 954
Score = 274 bits (694), Expect = 3e-72
Identities = 227/922 (24%), Positives = 397/922 (42%), Gaps = 191/922 (20%)
Query: 10 YDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMI 69
++P +E+ + + W E+ ++ + ++ P Y PP V+G++H+G A+ + + D +
Sbjct: 11 FNPSAVEQALYQRWEESGYFKPSEN--ENAPSYCIAIPPPNVTGSLHMGHAFQQTLMDTL 68
Query: 70 IRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNN 129
IRF M+G+N Q G D G+ ++ VE+ + + K + G E FI K ++ +
Sbjct: 69 IRFNRMEGHNTLWQTGTDHAGIATQMVVERKIAAEEGKTRHD-YGREAFINKIWDWKAYS 127
Query: 130 LKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCET 189
+++Q + LG +DW+ T+ + + R E+GL+ + KR+++W P+ T
Sbjct: 128 GGTISQQMRRLGNSIDWERERFTMDDGLSNAVKEVFVRLHEEGLIYRGKRLVNWDPKLHT 187
Query: 190 ALAEHEVRGEYKLRKDPSIYVKFPV-------EGKENEYLLIWTTTPWTLPANLAVSAHP 242
A+++ EV E K K + ++P+ +GK+ YL++ TT P T+ + AV+ HP
Sbjct: 188 AISDLEV--ENKESKGSLWHFRYPLANDAKTADGKD--YLVVATTRPETMLGDTAVAVHP 243
Query: 243 DYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEY 302
+ E Y ++L+ K VV RE+ I+ DEY
Sbjct: 244 E------------DERY----QSLIGKT---------VVLPLANREIP------IIADEY 272
Query: 303 PRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLD--- 359
V E GTG+V P H D+EVG+++ LP+ + L
Sbjct: 273 ---------------------VDREFGTGVVKITPAHDFNDYEVGKRHNLPMVNVLTLNA 311
Query: 360 ---DQGKY--TEGK------------WKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYP 402
D+ + T+GK ++G+ A KI+ G L + + K P
Sbjct: 312 NIRDEAEIIGTDGKPLAGYEATIPADYRGLERFAARKKIVADFEALGLLDEIKPHDLKVP 371
Query: 403 HCWRCKTPLIFRATDQWFLKISKVKDKIIKE-NDEKVTWYPDWVKIRFDNGVRDSGDWVI 461
+ R P+ TDQW++ + + D IK D ++ + P + + + +RD DW I
Sbjct: 372 YGDRGGVPIEPMLTDQWYVSVKPLADVAIKAVEDGEIQFVPKQYENLYFSWMRDIQDWCI 431
Query: 462 SRQRYWGIPLPIWQSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKL 521
SRQ +WG +P W +G +YV + E+ + L + E
Sbjct: 432 SRQLWWGHRIPAWYDAEGNVYVARNEEEV----------RSKYNLDSAVE---------- 471
Query: 522 GPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADF 581
+++ +DV+D WF SG+ ++++LG+P + + P D
Sbjct: 472 ---------------------LKQDEDVLDTWFSSGLWTFSTLGWPEQTKELKMFHPTDV 510
Query: 582 IVEGEDQVTKWFYSQQAASIVAFDT-----------VPYRRVAMHGYVLDEKGDKMSKSL 630
++ G D + W A ++ F VP++ V + G + DE+G KMSKS
Sbjct: 511 LITGFDIIFFW-----VARMIMFTMHFVKDENGKPQVPFKTVYVTGLIRDEQGQKMSKSK 565
Query: 631 GNIIRP---------EEVVERA----------------------------GRDTFRFYML 653
GN++ P E+++E+ G D RF +
Sbjct: 566 GNVLDPIDMIDGISLEDLLEKRTGNMMQPQLAEKIAKATRKEFAEGIAAHGTDALRFTLA 625
Query: 654 WATNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKW 713
+ ++ + K +E R N LWN T LD L+ E+ F D+W
Sbjct: 626 ALASNGRDINWDMKRLEGYRNFCNKLWNASRFVLTNEKLD------LSQGEIEFSLADRW 679
Query: 714 ILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAA 773
I S N + + + + A+Y F WY+ L K ++ G AA
Sbjct: 680 IQSEFNRTVETFRSSLSQYRFDLCANAIYEFTWNQFCDWYLEL-TKPVFANGNAAQIRAA 738
Query: 774 YYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNV--ESVHMLDWPKVDEKAIDEELE 831
TL V + LLRL P P+I EEI+Q ++ F + +S+ + +P+V+E D E E
Sbjct: 739 SQTLVHVLEKLLRLAHPLIPFITEEIWQK-VKGFVGITADSIMLQPFPQVEESGFDPEAE 797
Query: 832 REMEFIRRIVEAGSAARQRAKI 853
E+E+++ ++ A R + I
Sbjct: 798 AEIEWLKEVIVAVRNIRAESNI 819
>sp|Q9ZK61|SYV_HELPJ VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|7437644|pir||E71852 valine--tRNA ligase (EC 6.1.1.9)
- Helicobacter pylori (strain J99)
>gi|4155674|gb|AAD06660.1| (AE001535) VALYL-TRNA
SYNTHETASE [Helicobacter pylori J99]
Length = 872
Score = 270 bits (682), Expect = 8e-71
Identities = 221/887 (24%), Positives = 403/887 (44%), Gaps = 143/887 (16%)
Query: 10 YDPKKLEEKVEKFWSENEIYR--KVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKD 67
Y P+++E+K+ + S + +++++ G ++ + PP V+G +H+G A ++D
Sbjct: 8 YQPEEIEKKIYEICSHRGYFEINGNEKIQEKGKRFCLMMPPPNVTGILHIGHALTLSLQD 67
Query: 68 MIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFAL 127
+++R++ M GY QPG D G+ + VE+ L + K+ E +G E FI+K E+
Sbjct: 68 ILVRYKRMDGYKTLYQPGLDHAGIATQNVVEKQLLSQGVKK--EDLGREKFIQKVWEWKE 125
Query: 128 NNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRC 187
+ + EQ K LG+ + T+ + + +EKGL+ +D +++WC +
Sbjct: 126 KSGGAILEQMKRLGVSTAFSRTRFTMDKGLQRAVKLAFLKWYEKGLIVQDNYMVNWCTK- 184
Query: 188 ETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYV 247
+ AL++ EV EY+ RK Y+++ +E ++
Sbjct: 185 DGALSDIEV--EYEERKGALYYIRYYLENQK----------------------------- 213
Query: 248 KVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKE 307
+Y ++A + + G+ + +E RY H++ Q+
Sbjct: 214 ----------DYLVVATTRPETLFGDSAIMVNPNDE---------RYKHLV-----GQQV 249
Query: 308 FKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTE- 366
+I V + GTG V PGH D+EVG+++ L D++G
Sbjct: 250 ILPLINRTIPIIADAHVEMGFGTGCVKVTPGHDFNDYEVGKRHHLETIKIFDEKGILNAH 309
Query: 367 -GKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISK 425
G+++ + EA K++ L+E L K E H+ HC+RC + + QWF+K
Sbjct: 310 CGEFENLERLEARDKVVAALKENALLEKIEEHVHQVGHCYRCHNVVEPYVSKQWFVKPEI 369
Query: 426 VKDKIIKENDEKVTWYP-DWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVV 484
+ I K +YP +W+ ++ +R+ W ISRQ +WG +P++ E+ +V
Sbjct: 370 AQSSIEKIQQGLARFYPSNWIN-NYNAWMRELRPWCISRQLFWGHQIPVFTCENNHQFV- 427
Query: 485 GSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMR 544
+++ + P EKL+
Sbjct: 428 -----------SLDTP---LSCPTCKSEKLE----------------------------- 444
Query: 545 RVKDVVDVWFDSGIASWASLGYPRNK-ELFEK-----LWPADFIVEGEDQVTKWFYSQQA 598
+ KDV+D WF SG+ ++++LG+ + K +LF + +P ++ G D + W
Sbjct: 445 QDKDVLDTWFSSGLWAFSTLGWGQEKSDLFNESDLKDFYPNTTLITGFDILFFWVARMLF 504
Query: 599 ASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNP 658
S +P++ + +H V DEKG+KMSKS GN+I P E++E+ G D+ RF +
Sbjct: 505 CSESLLGELPFKDIYLHALVRDEKGEKMSKSKGNVIDPLEMIEKYGADSLRFTLANLCAT 564
Query: 659 WENLKFSWKGVEQVRRMLNILWNVYVLASTYMSL--DNF-DPRKLNPDELPFREEDKWIL 715
++K S +E + N L+N A++Y+ L ++F D +LN + ++
Sbjct: 565 GRDIKLSTTHLENNKNFANKLFN----AASYLKLKQESFKDKERLNEYQTAL---GRYAK 617
Query: 716 SRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYY 775
SR+N + EV N ++++ AT LY F+ + W++ + VE E D+L +
Sbjct: 618 SRLNLVTKEVRNALDNYRFNDATTLLYRFLWGEFCDWFIEFSK----VENEAIDELGS-- 671
Query: 776 TLWKVFDVLLRLLAPFTPYIAEEIYQNLIR-PFTNVESVHMLDWPKVDEKAIDEELEREM 834
V L+LL PF P+I+E +Y L N S+ ++ +PK E A DE+LE E
Sbjct: 672 ----VLKEALKLLHPFMPFISESLYHKLSNTELENAHSIMVMPYPK--EIAQDEKLEHEF 725
Query: 835 EFIRRIVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRI 881
E I+ + + +R KI L P I+++ +++ +E R+
Sbjct: 726 EVIKDCI----VSLRRLKIMLETP--PIVLKEASVGLREKIENTERL 766
>sp|O53175|SYV_MYCTU VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|7437648|pir||G70863 probable valS protein -
Mycobacterium tuberculosis (strain H37RV)
>gi|2791488|emb|CAA16025.1| (AL021246) valS
[Mycobacterium tuberculosis]
Length = 876
Score = 253 bits (639), Expect = 9e-66
Identities = 224/877 (25%), Positives = 376/877 (42%), Gaps = 155/877 (17%)
Query: 8 REYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKD 67
+ +DP +E + + W + + K P Y + PP V+G++H+G A + D
Sbjct: 4 KSWDPAAMESAIYQKWLDAGYFTADPTSTK--PAYSIVLPPPNVTGSLHMGHALEHTMMD 61
Query: 68 MIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFAL 127
+ R + MQGY V QPG D G+ + VEQ L + K + E +G E F+ K ++
Sbjct: 62 ALTRRKRMQGYEVLWQPGTDHAGIATQSVVEQQLAVDGKTK--EDLGRELFVDKVWDWKR 119
Query: 128 NNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRC 187
+ + Q + LG +DW T+ + KR ++ GL+ + +R+++W P
Sbjct: 120 ESGGAIGGQMRRLGDGVDWSRDRFTMDEGLSRAVRTIFKRLYDAGLIYRAERLVNWSPVL 179
Query: 188 ETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYV 247
+TA+++ EV Y+ + + ++ ++++ TT T+ + A++ HPD
Sbjct: 180 QTAISDLEVN--YRDVEGELVSFRYGSLDDSQPHIVVATTRVETMLGDTAIAVHPD---- 233
Query: 248 KVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKE 307
E Y R L G H +D
Sbjct: 234 --------DERY---------------------------RHLVGTSLAHPFVDR------ 252
Query: 308 FKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKY--T 365
E A ++ + V E GTG V P H DFE+G ++ LP+ S LD +G+ T
Sbjct: 253 -----ELA--IVADEHVDPEFGTGAVKVTPAHDPNDFEIGVRHQLPMPSILDTKGRIVDT 305
Query: 366 EGKWKGIYVKEADPKIIEHLREKGYLVKAGE-IEHKYPHCWRCKTPLIFRATDQWFLKI- 423
++ G+ EA + + L +G +V+ H H R P+ R + QW++++
Sbjct: 306 GTRFDGMDRFEARVAVRQALAAQGRVVEEKRPYLHSVGHSERSGEPIEPRLSLQWWVRVE 365
Query: 424 --SKVKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEI 481
+K ++ D + +P ++ R+ + V D DW ISRQ +WG +PIW DGE
Sbjct: 366 SLAKAAGDAVRNGDTVI--HPASMEPRWFSWVDDMHDWCISRQLWWGHRIPIWYGPDGEQ 423
Query: 482 YVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGK 541
VG P+ +E+
Sbjct: 424 VCVGPDETP----------------PQGWEQD---------------------------- 439
Query: 542 DMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKW--------- 592
DV+D WF S + +++LG+P EK +P +V G D + W
Sbjct: 440 -----PDVLDTWFSSALWPFSTLGWPDKTAELEKFYPTSVLVTGYDILFFWVARMMMFGT 494
Query: 593 FYSQQAASIVAFD-----TVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDT 647
F AA + D VP+ V +HG + DE G KMSKS GN+I P + VE G D
Sbjct: 495 FVGDDAA--ITLDGRRGPQVPFTDVFLHGLIRDESGRKMSKSKGNVIDPLDWVEMFGADA 552
Query: 648 FRFYMLWATNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKL-NPDELP 706
RF + +P +L S V R L+N A+ Y L+ P L +P+EL
Sbjct: 553 LRFTLARGASPGGDLAVSEDAVRASRNFGTKLFN----ATRYALLNGAAPAPLPSPNEL- 607
Query: 707 FREEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGE 766
+ D+WIL R+ + +EV++ + + ++A +LY+F ++ WY+ L + +L +G
Sbjct: 608 -TDADRWILGRLEEVRAEVDSAFDGYEFSRACESLYHFAWDEFCDWYLELAKTQL-AQG- 664
Query: 767 DPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAI 826
L D LLRLL P P++ E ++ L T ES+ DWP+ ++
Sbjct: 665 ---LTHTTAVLAAGLDTLLRLLHPVIPFLTEALWLAL----TGRESLVSADWPEPSGISV 717
Query: 827 D-------EELEREMEFIRRI-VEAGSAARQRAKIKL 855
D ++++ + +RR + G A RQ+ ++
Sbjct: 718 DLVAAQRINDMQKLVTEVRRFRSDQGLADRQKVPARM 754
>pir||E75554 valyl-tRNA synthetase - Deinococcus radiodurans (strain R1)
>gi|6457813|gb|AAF09735.1|AE001877_2 (AE001877)
valyl-tRNA synthetase [Deinococcus radiodurans]
Length = 913
Score = 252 bits (638), Expect = 1e-65
Identities = 238/978 (24%), Positives = 406/978 (41%), Gaps = 158/978 (16%)
Query: 9 EYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDM 68
++DP +E K W +E +R KD + + PP V+G +HLG A + + D
Sbjct: 12 QFDPTGIEPKWAARW-RSEPFRADATSGKD--PFTIVIPPPNVTGNLHLGHALDNTLIDT 68
Query: 69 IIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALN 128
+IR++ M G+ PG D G+ +V VE+ L K +G E F++K E+
Sbjct: 69 LIRYKRMAGFEALYLPGMDHAGISTQVVVERQL--KDAGTSRHDLGREAFLEKVWEWKGK 126
Query: 129 NLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCE 188
+ ++ +Q LG+ DW T+ + + + GL + +R+++W P +
Sbjct: 127 SGGMILDQLTRLGVSADWTRERFTMDEGLSRAVRTQFVKLYHDGLAYRGERIVNWDPASQ 186
Query: 189 TALAEHEVRGEYKLRKDPSIYVKFPVEGK-------ENEYLLIWTTTPWTLPANLAVSAH 241
T L+E E+ E +RK + + +E E + I T P T+ A+ A++ H
Sbjct: 187 TTLSELEIDRE--VRKGKMYTLSYKLENSAERGSNGETGEIRIATVRPETIFADQAIAVH 244
Query: 242 PDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDE 301
P+ + + V R L D R+V I+ DE
Sbjct: 245 PEDERFRHLVGQKARIP-------LTD------------------------RWVPIIADE 273
Query: 302 YPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQ 361
V +E G G + P H DFEVG+++GL S +D
Sbjct: 274 A---------------------VEMEFGVGALKITPAHDPTDFEVGERHGLERPSVIDLD 312
Query: 362 GKYTE-----GKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRAT 416
G T +++G+ A +++ L E G L++ + + R K P+ +
Sbjct: 313 GNLTRDELVPAEFQGLERFAARKAVVKALEESGDLLEQKDHDTAIGLSERTKVPVEPIIS 372
Query: 417 DQWFLKISKVKDKIIKENDE-KVTWYPD-WVKIRFDNGVRDSGDWVISRQRYWGIPLPIW 474
+QWF+K+ D++++ D+ ++ P+ + K+ D + + DW ISRQ +WG +P W
Sbjct: 373 EQWFVKMKPFADQVLEGLDKGEIKLVPERYTKVNRD-WLENIRDWNISRQLWWGHQIPAW 431
Query: 475 QSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAF 534
++G IYV P+ +L ++ P H
Sbjct: 432 YDKEGNIYV-----------------------PDPENPELDCDQD---PRYAHL------ 459
Query: 535 IIKVNGKDMRRVKDVVDVWFDSGIASWASLGYP-RNKELFEKLWPADFIVEGEDQVTKWF 593
++RR DV D WF S + +++LG+P + E F K +P +V G D + W
Sbjct: 460 -------NLRRDPDVFDTWFSSNLWPFSTLGWPDTDSEDFRKFYPTQVLVTGYDILFFWV 512
Query: 594 YSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYML 653
Q A P+ V +HG LD KG KMSKS GN I P E+ + G D RF
Sbjct: 513 ARMQMAGYGLTGQAPFSTVMLHGLYLDAKGQKMSKSKGNGIDPLELFGQYGVDACRFAFT 572
Query: 654 WATNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMS---LDNFDPRKLN-------PD 703
+ + +++K + EQ R N LWN A + ++ D PD
Sbjct: 573 FLSTGGQDIKHDARRFEQGRNFANKLWNATRFALMRLGEARIEGSDDLSAYVRAAVTLPD 632
Query: 704 ELPFREE---------------DKWILSRVNSLISEVENGIESFYLTKATRALYNFVVED 748
+ R + D+WI+SR+N + +E +++F + A R LY+F ++
Sbjct: 633 GVLLRSKDVLAQLKERDDLTLADRWIISRLNDVTAEASAQLDAFDIGAAIRTLYSFTWDE 692
Query: 749 LSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFT 808
WY+ + L L TL V + +L+LL PF P+I E+Y L
Sbjct: 693 FCDWYIEAAKPEL-----ASGNLGTMATLKVVLEHVLKLLHPFMPFITSELYAAL----G 743
Query: 809 NVESVHMLDWPKVDEKAIDEELEREMEFIRRIVEAGSAARQRAKIKLRYPVRRIIIETED 868
+ + + WP+ D D E + + +R V++ + + + P R+ + D
Sbjct: 744 HRRQIAVHSWPQPDAALHDAEATKAFDALRSAVDSARSLKSELGLS---PQDRLNVAV-D 799
Query: 869 ETVKKAVERLNRILRD--QLNAKEVKVGRVERELTIKPNFAKLGPEFKGDAKIIAKWINE 926
+ V + R++ ++N GR + + P L P +G IA W+ +
Sbjct: 800 GDLADVVRQNARVVEGIARVNLVPALEGRTLSQ--VAPGVTILAP-LEGTVD-IADWVKK 855
Query: 927 NGRELYEKGELTVEIDGK 944
+ L E + + GK
Sbjct: 856 QQKRLAELDKQIKQAQGK 873
>sp|P28350|SYV_NEUCR VALYL-TRNA SYNTHETASE, MITOCHONDRIAL PRECURSOR (VALINE--TRNA
LIGASE) (VALRS) >gi|101878|pir||A41251 valine--tRNA
ligase (EC 6.1.1.9) - Neurospora crassa
Length = 1093
Score = 249 bits (628), Expect = 2e-64
Identities = 217/875 (24%), Positives = 361/875 (40%), Gaps = 135/875 (15%)
Query: 3 KEPEFREYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWN 62
+ P F Y+P +E ++W + ++ + K+ PP V+GA+H G A
Sbjct: 133 EHPHFSAYNPSAVEAAWYQWWEKAGYFKPESCRKPSAGKFVIPLPPPNVTGALHCGHALA 192
Query: 63 KIIKDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKC 122
++D +IR+ M+GY PG D G+ + VE+ L K KK I +++G E F
Sbjct: 193 NSLQDTLIRWYRMKGYETLWVPGCDHAGISTQSVVEKMLWKKEKK-IRQELGREKFTDLV 251
Query: 123 KEFALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLH 182
E+ + + K++G MDW T+ + T R ++GL+ + R+++
Sbjct: 252 WEWKGEYHQRINNAQKLMGGSMDWSREAFTMDKNLTAATMETFCRLHDEGLIYRSNRLVN 311
Query: 183 WCPRCETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHP 242
WC TAL+ EV E KE + + V H
Sbjct: 312 WCTHLNTALSGLEV------------------ETKEITGRTLLDVPGYDKKVEFGVLTH- 352
Query: 243 DYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEY 302
K + +G EE +A + +LG+ G+ E RY H L+ ++
Sbjct: 353 ------FKYQIDGSEETIEVATTRPETMLGDTGIAVNP---------EDPRYTH-LVGKF 396
Query: 303 PRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQG 362
R ++ ++V E GTG V P H D+++GQ++ L + L++ G
Sbjct: 397 ARHPFVDRLLP----IVTDNYVDKEFGTGAVKLTPAHDFNDYQLGQRHNLEFINILNENG 452
Query: 363 KYTE--GKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWF 420
+ G +KG +A ++E L + G VK K P C + K + T+QW+
Sbjct: 453 TLNDNAGPFKGQKRFDARYTVVEELTKLGLFVKKEPNPMKIPLCEKSKDVIEPMMTEQWW 512
Query: 421 LKISKVKDKIIKENDE-KVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLP----IWQ 475
+++ ++ + ++ +E KV P+ + + D DW ISRQ +WG +P I++
Sbjct: 513 VRMKEMGEAALQVVEEGKVKISPESATKSYKRWLADIQDWCISRQLWWGHRIPAYRVIFE 572
Query: 476 SEDGE------IYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRP 529
E+G+ +VVG +E + + G + L +
Sbjct: 573 GEEGQRENEKSEWVVGRTQEEAQAKAEAKFAGRKFTLEQD-------------------- 612
Query: 530 YVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKEL-FEKLWPADFIVEGEDQ 588
D +D WF SG+ A LG+P + L F+K +P + G D
Sbjct: 613 -----------------PDCLDTWFSSGLWPMAILGWPNTENLDFKKFFPTSMLETGWDI 655
Query: 589 VTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRP------------ 636
+ W S+ VP+ V H + D +G KMSKSLGN+I P
Sbjct: 656 LFFWVSRMIMLSLKMTGEVPFTEVYCHSLIRDSEGRKMSKSLGNVIDPLDIIRGIELEDL 715
Query: 637 ----------EEVVERA---------------GRDTFRFYMLWATNPWENLKFSWKGVEQ 671
EE V RA G D RF +L T ++ F + +
Sbjct: 716 HAKLLVGNLKEEEVARATKYQKTAFPGGIPECGADAMRFTLLSYTTGGGDINFDIRVMHA 775
Query: 672 VRRMLNILWNV--YVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISEVENGI 729
RR N +W YVL +F P K D F +KWIL R+N + + +
Sbjct: 776 YRRFCNKIWQASKYVLGKL---PQDFMP-KGELDTANFSVPEKWILHRMNVAVKGMNEAL 831
Query: 730 ESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFDVLLRLLA 789
E+ ++AT+ Y F ++L ++ K + +G ++ + TL+ DV LRLL
Sbjct: 832 EAREFSRATKVAYQFFYDELCDVFIE-NSKGILSDGTPEEQQSVQQTLYHALDVALRLLH 890
Query: 790 PFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEK 824
P PYI EE++Q L R + E++ + +P + +
Sbjct: 891 PIMPYITEELWQRLPRKQGDGETIMLAPYPAFESQ 925
>pir||E82001 valyl-tRNA synthetase NMA0094 [imported] - Neisseria meningitidis
(group A strain Z2491) >gi|7378867|emb|CAB83410.1|
(AL162752) valyl-tRNA synthetase [Neisseria meningitidis
Z2491]
Length = 945
Score = 247 bits (625), Expect = 4e-64
Identities = 220/940 (23%), Positives = 393/940 (41%), Gaps = 189/940 (20%)
Query: 9 EYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDM 68
+Y P ++E K + W E ++ +L K P + PP V+G +H+G A+N+ I D
Sbjct: 4 KYSPAEIESKHYQNWEEQGYFQPDMDLTK--PSFSIQLPPPNVTGTLHMGHAFNQTIMDG 61
Query: 69 IIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALN 128
+ R+ M+G N PG D G+ ++ VE+ L + + +G E F++K E+
Sbjct: 62 LTRYYRMKGCNTAWIPGTDHAGIATQIVVERQLAAQNVSRHD--LGREKFLEKVWEWKEV 119
Query: 129 NLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCE 188
+ +T+Q + +G DW Y T+ + E+ R +E+GL+ + KR+++W P
Sbjct: 120 SGGTITQQMRRVGCSADWTREYFTMDDVRAETVTEVFVRLYEQGLIYRGKRLVNWDPVLG 179
Query: 189 TALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVK 248
TA+++ EV E + ++++P+ E +++ TT P TL ++AV+ +P+
Sbjct: 180 TAVSDLEV--ESVEEQGSMWHIRYPLADNPAEAVIVATTRPETLLGDVAVAVNPE----- 232
Query: 249 VKVEFNGREEY-WILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKE 307
E Y ++ K L+ + G R + ++ DEY +K+
Sbjct: 233 -------DERYTHLIGKELILPLTG--------------------RTIPVIADEYV-EKD 264
Query: 308 FKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTEG 367
F GTG V P H D+EVG+++ + + D + K
Sbjct: 265 F--------------------GTGCVKITPAHDFNDYEVGKRHDTRLVNVFDLEAKVLAN 304
Query: 368 ------------------KWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKT 409
K+ G+ A +++ L+E+G+LV+ P R +
Sbjct: 305 AEVFNFKGEAQPSFALPEKYAGLDRFAARKQMVADLQEQGFLVEIKAHTLMTPKGDRTGS 364
Query: 410 PLIFRATDQWFLKIS---------------KVKDKIIKENDE-KVTWYPD-WVKIRFDNG 452
+ T QWF+ +S + DK K D V + P+ WV ++
Sbjct: 365 VIEPMLTSQWFVAMSATPNGGEPDSEFKGLSLADKAKKAVDSGAVRFIPENWVN-TYNQW 423
Query: 453 VRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEE 512
+ + DW ISRQ +WG +P W +G +YV + E
Sbjct: 424 MNNIQDWCISRQLWWGHQIPAWYDNEGNVYVARNQEE----------------------- 460
Query: 513 KLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKEL 572
E++ G L R +DV+D WF S + +++LG+P +
Sbjct: 461 ----AEKQAGKTGL-----------------TREEDVLDTWFSSALVPFSTLGWPSETDE 499
Query: 573 FEKLWPADFIVEGEDQVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGN 632
+ P++ +V G + + W + VP++ V +HG V D +G KMSKS GN
Sbjct: 500 LKAFLPSNVLVTGYEIIFFWVARMIMMTTHFTGKVPFKDVYIHGIVRDHEGKKMSKSEGN 559
Query: 633 IIRPEEVVE-------------------------------------RAGRDTFRFYMLWA 655
+I P ++++ G D RF M
Sbjct: 560 VIDPVDLIDGIDLEKLLVKRTTGLRKPETAPKVEEASRKLFPEGIPSMGADALRFTMASY 619
Query: 656 TNPWENLKFSWKGVEQVRRMLNILWNV--YVLASTYMSLDNFDPRKLNPDELPFREEDKW 713
+ ++ F +K E R N +WN +VL +T + P F D W
Sbjct: 620 ASLGRSVNFDFKRAEGYRNFCNKIWNATNFVLMNTENQDCGYGATATEPRGYSF--PDMW 677
Query: 714 ILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAA 773
I+ R+N I +V E++ A LY+F+ D WY+ L + +L G + A
Sbjct: 678 IVDRLNQTIEQVTQAYETYRFDLAAETLYSFMWNDYCDWYLELAKVQLQT-GCASRQRAT 736
Query: 774 YYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTN---VESVHMLDWPKVDEKAIDEEL 830
+TL +V + LRLL P P+I EE++Q + P + +S+ + +P+ D I +
Sbjct: 737 RHTLLRVLEAALRLLHPIIPFITEELWQT-VAPMCDAKTADSIMLARFPEADSGEIVQTA 795
Query: 831 EREMEFIRRIVEAGSAARQRAKIKLRYPVRR-IIIETEDE 869
+M ++ ++ G+ R ++ ++ V+ + +E+ D+
Sbjct: 796 FEQMTVLQDLI--GAVRNLRGEMGIQPNVKAPLFVESTDD 833
>pir||F81230 valyl-tRNA synthetase NMB0174 [imported] - Neisseria meningitidis
(group B strain MD58) >gi|7225392|gb|AAF40631.1|
(AE002374) valyl-tRNA synthetase [Neisseria meningitidis
MC58]
Length = 945
Score = 247 bits (624), Expect = 5e-64
Identities = 220/940 (23%), Positives = 394/940 (41%), Gaps = 189/940 (20%)
Query: 9 EYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDM 68
+Y+P ++E K + W E ++ +L K P + PP V+G +H+G A+N+ I D
Sbjct: 4 KYNPAEIESKHYQNWEEQGYFQPDMDLTK--PSFSIQLPPPNVTGTLHMGHAFNQTIMDG 61
Query: 69 IIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALN 128
+ R+ M+G N PG D G+ ++ VE+ L + + +G E F++K E+
Sbjct: 62 LTRYYRMKGCNTAWIPGTDHAGIATQIVVERQLAAQNVSRHD--LGREKFLEKVWEWKEV 119
Query: 129 NLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCE 188
+ +T+Q + +G DW Y T+ + E+ R +E+GL+ + KR+++W P
Sbjct: 120 SGGTITQQMRRVGCSADWTREYFTMDDVRAETVTEVFVRLYEQGLIYRGKRLVNWDPVLG 179
Query: 189 TALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVK 248
TA+++ EV E + ++++P+ E +++ TT P TL ++AV+ +P+
Sbjct: 180 TAVSDLEV--ESVEEQGSMWHIRYPLADNPAEAVIVATTRPETLLGDVAVAVNPE----- 232
Query: 249 VKVEFNGREEY-WILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKE 307
E Y ++ K L+ + G R + ++ DEY +K+
Sbjct: 233 -------DERYTHLIGKELILPLTG--------------------RTIPVIADEYV-EKD 264
Query: 308 FKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTEG 367
F GTG V P H D+EVG+++ + + + + K
Sbjct: 265 F--------------------GTGCVKITPAHDFNDYEVGKRHDTRLINVFNLEAKVLAN 304
Query: 368 ------------------KWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKT 409
K+ G+ A +++ L+E+G+LV+ P R +
Sbjct: 305 AEVFNFKGEAQLGFALPEKYAGLDRFAARKQMVADLQEQGFLVEIKPHTLMTPKGDRTGS 364
Query: 410 PLIFRATDQWFLKIS---------------KVKDKIIKENDE-KVTWYPD-WVKIRFDNG 452
+ T QWF+ +S + DK K D V + P+ WV ++
Sbjct: 365 VIEPMLTSQWFVAMSATPNGGEPDSEFKGLSLADKAKKAVDSGAVRFIPENWVN-TYNQW 423
Query: 453 VRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEE 512
+ + DW ISRQ +WG +P W +G +YV + E
Sbjct: 424 MNNIQDWCISRQLWWGHQIPAWYDNEGNVYVARNQEE----------------------- 460
Query: 513 KLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKEL 572
E++ G L R +DV+D WF S + +++LG+P +
Sbjct: 461 ----AEKQAGKTGL-----------------TREEDVLDTWFSSALVPFSTLGWPSETDE 499
Query: 573 FEKLWPADFIVEGEDQVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGN 632
+ P++ +V G + + W + VP++ V +HG V D +G KMSKS GN
Sbjct: 500 LKAFLPSNVLVTGYEIIFFWVARMIMMTTHFTGKVPFKDVYIHGIVRDHEGKKMSKSEGN 559
Query: 633 IIRPEEVVE-------------------------------------RAGRDTFRFYMLWA 655
+I P ++++ G D RF M
Sbjct: 560 VIDPVDLIDGIGLEKLLVKRTTGLRKPETAPKVEEATKKLFPEGIPSMGADALRFTMASY 619
Query: 656 TNPWENLKFSWKGVEQVRRMLNILWNV--YVLASTYMSLDNFDPRKLNPDELPFREEDKW 713
+ ++ F +K E R N +WN +VL +T + P F D W
Sbjct: 620 ASLGRSVNFDFKRAEGYRNFCNKIWNATNFVLMNTENQDCGYGATAAEPRGYSF--PDMW 677
Query: 714 ILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAA 773
I+ R+N I +V E++ A LY+FV D WY+ L + +L G + A
Sbjct: 678 IVGRLNQTIEQVTQAYETYRFDLAAETLYSFVWNDYCDWYLELAKVQLQT-GCASRQRAT 736
Query: 774 YYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTN---VESVHMLDWPKVDEKAIDEEL 830
+TL +V + LRLL P P+I EE++Q + P + +S+ + +P+ D I +
Sbjct: 737 RHTLLRVLEAALRLLHPIIPFITEELWQT-VAPMCDAKTADSIMLARFPEADSGEIVQTA 795
Query: 831 EREMEFIRRIVEAGSAARQRAKIKLRYPVRR-IIIETEDE 869
+M ++ ++ G+ R ++ ++ V+ + +E+ D+
Sbjct: 796 FEQMTVLQDLI--GAVRNLRGEMGIQPNVKAPLFVESTDD 833
>sp|P57447|SYV_BUCAI VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|10039036|dbj|BAB13070.1| (AP001119) valyl-tRNA
synthetase [Buchnera sp. APS]
Length = 955
Score = 247 bits (624), Expect = 5e-64
Identities = 207/908 (22%), Positives = 387/908 (41%), Gaps = 184/908 (20%)
Query: 10 YDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMI 69
Y+PK +EE + FW +N + K L K + + PP ++G++H+G A+ + I D++
Sbjct: 5 YNPKHIEESLYFFWEKNGFF-KPNHLEKS--TFCIMMPPPNITGSLHMGHAFQQTIMDIL 61
Query: 70 IRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNN 129
IR+ MQG N + Q G D G+ ++ VE+ + K +K ++ ++FIKK E+ +
Sbjct: 62 IRYHRMQGKNTFWQVGTDHAGIATQILVERQIFEKEQK-TKKDYSRDDFIKKIWEWKKQS 120
Query: 130 LKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCET 189
I+T+Q + LGI +DWD T+ + S ++ L+ + K+++HW + ET
Sbjct: 121 SNIITKQMRRLGISVDWDYEKFTLDPDISNSVREAFIILYKNNLIYQKKKLVHWDSKLET 180
Query: 190 ALAEHEVRGEYKLRKDPSIYVKFPVEGKEN------EYLLIWTTTPWTLPANLAVSAHP- 242
+++ EV E++L K ++++P+ + +YL++ TT P TL + A++ +P
Sbjct: 181 VISDLEV--EHRLIKGKKWFIRYPIIENDMSLRSKVKYLIVSTTRPETLLGDTAIAVNPE 238
Query: 243 DYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEY 302
DY Y +F G L R + I+ D Y
Sbjct: 239 DYKY----NQFIGNHVSCPLTN----------------------------RIIPIIKDRY 266
Query: 303 PRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQG 362
LE+GTG V P H D++VG + LP+ + G
Sbjct: 267 ---------------------ADLEKGTGCVKITPAHDFNDYKVGLHHKLPMINIFTFDG 305
Query: 363 KYTEG----KWKG----------------IYVKEADPKIIEHLREKGYLVKAGEIEHKYP 402
+ +KG + + A +II+ + + G+L K E P
Sbjct: 306 RIKSTAEVYNYKGEKSNQYSTCIPMQFQHLDILSARIEIIKEITKLGFLEKIEECNVTVP 365
Query: 403 HCWRCKTPLIFRATDQWFLKISKV-KDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVI 461
+ R + T+QW+LK S + K + D+K+ + P + + + + + DW I
Sbjct: 366 YSERSGVIIEPMLTNQWYLKTSTLAKVALNAVKDKKIKFIPQQYESMYSSWMNNIEDWCI 425
Query: 462 SRQRYWGIPLPIWQSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKL 521
SRQ +WG +P+W + IY + E+ ++Y V+
Sbjct: 426 SRQLWWGHRIPVWYDDQKNIY----------------IGQNEKEIRQAYSISENVL---- 465
Query: 522 GPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADF 581
+++ DV+D WF SG+ +++SLG+P+ + P +
Sbjct: 466 ---------------------LKQENDVLDTWFSSGLWTFSSLGWPKKTTFLKTFHPTNV 504
Query: 582 IVEGEDQVTKWFYSQQAASIVAF------DTVPYRRVAMHGYVLDEKGDKMSKSLGNIIR 635
+V G D + W ++ VP++ + + G + DE G KMSKS GN+I
Sbjct: 505 LVSGFDIIFFWIARMIMLTMYFMKDKHNNPEVPFKNIYITGLIRDEFGKKMSKSKGNVID 564
Query: 636 P--------------------------EEVVER-----------AGRDTFRFYMLWATNP 658
P +++++R G D RF +
Sbjct: 565 PLDMIDGISLSELIKKRTNNLLQPNLSDKIIQRTIKQFPEGIKSTGTDALRFTFSALASS 624
Query: 659 WENLKFSWKGVEQVRRMLNILWNV--YVLASTY-MSLDNFDPRKLNPDELPFREEDKWIL 715
++++ ++ R N LWN +VL +T + FD ++ +KWIL
Sbjct: 625 TRDIQWDMNRLKGYRNFCNKLWNASRFVLINTQDHNFSKFDVKR------KMLLINKWIL 678
Query: 716 SRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYY 775
N+ + ++++ A LY+F+ WY+ ++ + + G +
Sbjct: 679 IEFNNTVKLYRESLDTYRFDIAANILYDFIWNIFCDWYLEFVKIVIKL-GSSKEVYCTKN 737
Query: 776 TLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNV--ESVHMLDWPKVDEKAIDEELERE 833
L V ++LL+L P P+I E I+Q I+ N+ +++ + D+P+ + K D+++ +
Sbjct: 738 VLVYVLELLLKLAHPIMPFITETIWQR-IKLIQNISEKTIMLQDFPEYNHKLFDKKILVQ 796
Query: 834 MEFIRRIV 841
M ++++I+
Sbjct: 797 MNWMKKII 804
>sp|Q9ZCN6|SYV_RICPR VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|7437655|pir||B71675 valine--tRNA ligase (EC 6.1.1.9)
(valS) RP687 - Rickettsia prowazekii
>gi|3861224|emb|CAA15124.1| (AJ235272) VALYL-TRNA
SYNTHETASE (valS) [Rickettsia prowazekii]
Length = 814
Score = 246 bits (621), Expect = 1e-63
Identities = 218/830 (26%), Positives = 366/830 (43%), Gaps = 131/830 (15%)
Query: 8 REYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPP-YVSGAIHLGTAWNKIIK 66
+ Y+ + E+K + W E +IY + K + Y +D PP VSG +H+G ++
Sbjct: 6 KHYNFTENEKKWQNIWQELQIYAYDPNISK--AEIYIVDTPPPTVSGQLHIGHIYSYTQT 63
Query: 67 DMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFA 126
D I+RF+ M G N++ G+D +GLP E VE+ +K ++ FIK C E
Sbjct: 64 DFIVRFQRMIGKNIFYPIGFDDNGLPTERLVEKQKQIKAYNMERDE-----FIKICLEVV 118
Query: 127 LNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPR 186
N FK + + +DW Y TI + + + KG + + + + W
Sbjct: 119 KNEEAKFRSLFKQIALSVDWSLEYQTISPLSRKISQMSFLDLLHKGEVYRANQPILWDTV 178
Query: 187 CETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDY 246
TALA+ ++ + K+ Y+ F E + + L I TT P LPA +AV HPD
Sbjct: 179 DGTALAQADIEDKQKISS--MNYITFKTE--QGDQLTIATTRPELLPACVAVFYHPD--- 231
Query: 247 VKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQK 306
+RY H L D+
Sbjct: 232 --------------------------------------------DVRYKH-LADKSAITP 246
Query: 307 EFKEKYEWAHRVILAD-FVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYT 365
F EK ILAD V ++GTGLV + D + + LP+ + + +G
Sbjct: 247 LFNEKVP-----ILADPLVQQDKGTGLVMCCTFGDQTDITWWKSHNLPLKTIITKKGTIN 301
Query: 366 ---EGKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLK 422
+ G+ +KEA KII+ L+E+ L K EI R PL QWF+K
Sbjct: 302 FPHKLDIDGLTIKEARTKIIDILKEQSLLTKQEEIIQTVKCAERSGAPLEILTVTQWFIK 361
Query: 423 ISKVKDKIIKENDEKVTWYPDWVKIRFDNGVRD-SGDWVISRQRYWGIPLPIWQS----E 477
K+ ++K +E + WYP +K+R +N + S DW ISRQRY+G+P PIW S E
Sbjct: 362 TITHKEALLKRTNE-LNWYPKNMKMRLENWINSLSWDWCISRQRYFGVPFPIWYSKRIGE 420
Query: 478 DGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIK 537
+G+I + ++ +L V +LP Y + E++ P+
Sbjct: 421 EGKIL----YADISQLPV-----DPLKDLPIGYSK------EEVDPD------------- 452
Query: 538 VNGKDMRRVKDVVDVWFDSGIASWASL-----GYPRNKELFEKLWPADFIVEGEDQVTKW 592
DV+D W S ++ S NK +KL+P D + + + W
Sbjct: 453 ---------LDVMDTWATSSVSPQLSTYGISEDLAINKVRHDKLFPMDLRPQAHEIIRTW 503
Query: 593 FYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYM 652
+ S + + +P++ + + G+ L E KMSKS GN++ PE+++ER G D R+
Sbjct: 504 AFYTILKSHLHQNILPWKNIMVSGWCLAEDRSKMSKSKGNVLVPEKLLERYGADVIRY-- 561
Query: 653 LWATNP--WENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFR-- 708
W+ N + +S ++ +R++N LWN S + + +K++ ++ +
Sbjct: 562 -WSANSKLGADTAYSEDVMKNGKRLVNKLWNAAKFVSIHFDKLTSEDKKVSLFDIKEKIT 620
Query: 709 -EEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVE-GE 766
E D+W+++++ +L+ N ++++ A F Y+ + + R + E +
Sbjct: 621 NEFDQWMINKLVALVKLATNALQNYEYANAIYLTEKFFWSIFCDNYLEISKTRSYDEANK 680
Query: 767 DPD-KLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHM 815
+P + ++ TL+ + LL+L APF P+I EE+YQ L N S+HM
Sbjct: 681 NPQGQYSSILTLYHIMQTLLKLFAPFMPHITEELYQILY----NKNSIHM 726
>pir||E82068 valyl-tRNA synthetase VC2503 [imported] - Vibrio cholerae (group
O1 strain N16961) >gi|9657085|gb|AAF95645.1| (AE004320)
valyl-tRNA synthetase [Vibrio cholerae]
Length = 953
Score = 245 bits (619), Expect = 2e-63
Identities = 222/965 (23%), Positives = 400/965 (41%), Gaps = 189/965 (19%)
Query: 8 REYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKD 67
+ Y+P +E+ + K W E ++ + KD Y + PP V+G++H+G A+ I D
Sbjct: 3 KTYNPTSIEQDLYKTWEEQGYFKPHGDTSKDA--YSIMIPPPNVTGSLHMGHAFQDTIMD 60
Query: 68 MIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFAL 127
+IR + M+G N Q G D G+ ++ VE+ + + K + G + FI K E+
Sbjct: 61 TLIRCQRMKGKNTLWQVGTDHAGIATQMVVERKIAAEEGKT-KHDYGRDAFIDKIWEWKA 119
Query: 128 NNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRC 187
+ +T+Q + LG +DWD T+ + + ++ R ++ L+ + KR+++W P+
Sbjct: 120 ESGGTITKQLRRLGASVDWDRERFTMDDGFYKAVQEVFVRLYKDDLIYRGKRLVNWDPKL 179
Query: 188 ETALAEHEVRGEYKLRKDPSIYVKFPV-------EGKENEYLLIWTTTPWTLPANLAVSA 240
TA+++ EV E K K + ++P+ +GK+ Y+++ TT P T+ + V+
Sbjct: 180 HTAISDLEV--ENKETKGHMWHFRYPLADGVKTADGKD--YIVVATTRPETMLGDTGVAV 235
Query: 241 HPDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMD 300
+P+ K ++ K ++ ++G R + I+ D
Sbjct: 236 NPEDPRYKD-----------LIGKEIILPIVG--------------------RRIPIVGD 264
Query: 301 EYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPL-- 358
E+ +E+GTG V P H D+EVG+++ LP+ + L
Sbjct: 265 EH---------------------ADMEKGTGCVKITPAHDFNDYEVGKRHQLPMINILTF 303
Query: 359 ------------------DDQGKYTEGKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHK 400
+ G K++G+ A I+ E G L + + +
Sbjct: 304 DANIRDAAEVFNSNGEASNAYGTEIPAKYQGMERFAARKAIVAEFEELGLLQEIKDHDLT 363
Query: 401 YPHCWRCKTPLIFRATDQWFLK---ISKVKDKIIKENDEKVTWYPDWVKIRFDNGVRDSG 457
P+ R + TDQW+++ ++K + ++ D + + P + + + +RD
Sbjct: 364 VPYGDRGGVVIEPMLTDQWYVRAGILAKPAVEAVENGD--IQFVPKQYENMYFSWMRDIQ 421
Query: 458 DWVISRQRYWGIPLPIWQSEDGEIYVVGSWREL-VELAVAIEVNGERIELPESYEEKLKV 516
DW ISRQ +WG +P W E G ++V + E+ E +A +V
Sbjct: 422 DWCISRQLWWGHRIPAWYDEQGNVFVGRNEEEVRAENNIAADVA---------------- 465
Query: 517 IEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKL 576
+R+ DV+D WF S + ++ +LG+P +
Sbjct: 466 --------------------------LRQDDDVLDTWFSSALWTFGTLGWPEKTPELKVF 499
Query: 577 WPADFIVEGEDQVTKWFYSQQAASIVAF-------DTVPYRRVAMHGYVLDEKGDKMSKS 629
P D +V G D + W ++ + F VP++ V + G + DE GDKMSKS
Sbjct: 500 HPTDVLVTGFDIIFFWV-ARMIMMTMHFCKDEDGKAQVPFKTVYVTGLIRDENGDKMSKS 558
Query: 630 LGNIIRP-------------------------------------EEVVERAGRDTFRFYM 652
GN++ P E +E G D+ RF +
Sbjct: 559 KGNVLDPIDMIDGIDLESLVAKRTGNMMQPQLAAKIEKNTRKTFENGIEAYGTDSLRFTL 618
Query: 653 LWATNPWENLKFSWKGVEQVRRMLNILWNV--YVLASTYMSLDNFDPRKLNPDELPFREE 710
+ ++ + K +E R N LWN YVL +T + D EL +
Sbjct: 619 AAMASTGRDINWDMKRLEGYRNFCNKLWNASRYVLMNT----EEQDCGFAAGAELEYSLA 674
Query: 711 DKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDK 770
DKWI S+ E I++F L A LY F+ WY+ L + LW +G + +
Sbjct: 675 DKWIESQFELAAKEFNGHIDNFRLDMAANTLYEFIWNQFCDWYLELTKPVLW-KGTEAQQ 733
Query: 771 LAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVE--SVHMLDWPKVDEKAIDE 828
A TL V + LRL P PYI E I+Q++ VE ++ + P+ D ++
Sbjct: 734 RATRRTLITVLEKTLRLAHPVIPYITETIWQSVKPLVDGVEGDTIMLQALPQYDVANFNQ 793
Query: 829 ELEREMEFIRRIVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQLNA 888
E ++E+++ + + R I P+ ++++ +E +E +L
Sbjct: 794 EALDDIEWVKAFITSIRNLRAEYDINPGKPL-EVMLKAANEQDAARIEANKPVLVSLAKL 852
Query: 889 KEVKV 893
+ ++V
Sbjct: 853 ESIRV 857
>sp|O83998|SYV_TREPA VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|7437656|pir||B71250 valine--tRNA ligase (EC 6.1.1.9)
(valS) - syphilis spirochete >gi|3323365|gb|AAC26589.1|
(AE001271) valyl-tRNA synthetase (valS) [Treponema
pallidum]
Length = 956
Score = 243 bits (613), Expect = 1e-62
Identities = 191/779 (24%), Positives = 335/779 (42%), Gaps = 130/779 (16%)
Query: 48 PPYVSGAIHLGTAWNKIIKDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKK 107
PP ++G +H+G N +++D++IR++ M G PG D G+ + VE+AL K+
Sbjct: 68 PPNITGVLHMGHCLNTVLQDIVIRYQRMAGACTLWIPGTDHAGIATQHVVERAL---RKE 124
Query: 108 EIEEK-IGVENFIKKCKEFALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLK 166
I ++ + E F+ + ++ ++ + Q + +G DW T+ S
Sbjct: 125 GIHKREVTREQFVARTQQIKDSHQDTIRMQLRKMGASCDWTCERFTLDAGMSASVREAFV 184
Query: 167 RAWEKGLLEKDKRVLHWCPRCETALAEHEVRGEYKLRKDPSIY-VKFPV------EG--- 216
+E+GLL + +++WCPRC TAL++ EV + KD ++Y V++P+ EG
Sbjct: 185 TLYERGLLYRSMYLVNWCPRCGTALSDDEV---FHQEKDGALYYVRYPLLPRTEEEGNGV 241
Query: 217 -------KENEYLLIWTTTPWTLPANLAVSAHPDYDYVKVKVEFNGREEYWILAKALVDK 269
+ E ++I TT P T+ A++AV+ HPD + R + I K V
Sbjct: 242 PPPLGTAQVGETIIIATTRPETILADVAVAVHPD----------DARYQSLIGRKVCVPM 291
Query: 270 VLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFKEKYEWAHRVILADFVTLEEG 329
V R V I+ D Y Q DF G
Sbjct: 292 VN---------------------RIVPIIADSYVAQ----------------DF-----G 309
Query: 330 TGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTE---GKWKGIYVKEADPKIIEHLR 386
TG+V P H D+++G ++ L + L+ G + ++G+ +A +I+ L+
Sbjct: 310 TGMVKITPAHDPNDWDIGTRHSLEAINMLNPDGSLNDQVPAAYRGLSCAQARIQIVADLQ 369
Query: 387 EKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKDKIIKE-NDEKVTWYPDWV 445
G L + I H C+RC+ + + QWF+K+ + + + V ++P
Sbjct: 370 AHGLLSREERIVHSVGVCYRCEAVIEPYLSLQWFVKMKPLASQALAAWKRADVQFHPKKW 429
Query: 446 KIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVELAVAIEVNGERIE 505
+ + + DW ISRQ +WG +P+W
Sbjct: 430 ENTYVRWLEHIRDWCISRQLWWGHRIPVWYCA---------------------------- 461
Query: 506 LPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLG 565
+ ++ + D+ R D+ + DV+D WF S + +++LG
Sbjct: 462 ---------QCAQQTVSRVDVQR------CAHCGSADITQDPDVLDTWFSSWLWPFSTLG 506
Query: 566 YPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDK 625
+P+ + +P ++ D + W A + TVP+R V +HG V D++G K
Sbjct: 507 WPQETQKLRAFYPTSAVITAYDIIFFWVARMIMAGLEFTQTVPFRDVYLHGLVRDKQGRK 566
Query: 626 MSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENLKFSWKGVEQVRRMLNILWNVYVL 685
MSKSL N + P ++ G D RF + + +++ + R N +WN
Sbjct: 567 MSKSLNNGVDPLHIIRTYGADALRFTLAFMCAQGQDVLIEMDSFKMGSRFANKVWN---- 622
Query: 686 ASTYMSLDNFDPRKLNP-DELPFREEDKWILSRVNSLISEVENGIESFYLTKATRALYNF 744
AS Y+ L N + R++ + E D+WI N + +V +E++ A +A+Y F
Sbjct: 623 ASRYI-LGNLEGRRVYAIAHVSLTELDRWIFHTFNETVQQVRTALEAYRFNDAAQAVYEF 681
Query: 745 VVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNL 803
WYV K + + ++ +K A L + + LRLL PF P++ EEIY++L
Sbjct: 682 FWNSFCDWYVE-ASKCSFQKPDEQEKDRAASVLCTLLEETLRLLHPFLPFVTEEIYRSL 739
>pir||G81348 valine--tRNA ligase (EC 6.1.1.9) Cj0775c [imported] - Campylobacter
jejuni (strain NCTC 11168) >gi|6968221|emb|CAB73040.1|
(AL139076) valyl-tRNA synthetase [Campylobacter jejuni]
Length = 870
Score = 242 bits (610), Expect = 2e-62
Identities = 211/864 (24%), Positives = 373/864 (42%), Gaps = 148/864 (17%)
Query: 33 KELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRTMQGYNVWRQPGYDMHGLP 92
K +++ + + PP V+G +H+G A ++D++ R++ M GY V QPG D G+
Sbjct: 26 KTIQEKDKNFCIMMPPPNVTGVLHIGHALTFTLQDIMTRYKRMDGYKVLYQPGLDHAGIA 85
Query: 93 IEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIMTEQFKMLGIWMDWDNPYMT 152
+ VE+ L + K+ E++G E FI+K E+ + + +Q + LGI W T
Sbjct: 86 TQNVVEKQLLTQGIKK--EELGREEFIEKVWEWKEQSGGKILDQMRTLGITPAWSRLRFT 143
Query: 153 IKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHEVRGEYKLRKDPSIYVKF 212
+ + + ++K L+ + +++WC + AL++ EV EYK K ++K+
Sbjct: 144 MDEGLVNAVKKAFVELYDKRLIVRGNYMINWCTH-DGALSDIEV--EYKENKGKLYHIKY 200
Query: 213 PVEGKENEYLLIWTTTPWTLPANLAVSAHPDYD-YVKVKVEFNGREEYWILAKALVDKVL 271
++ + E+L++ TT P T + AV HPD + Y K VDK
Sbjct: 201 FLKDSD-EFLVVATTRPETFFGDTAVMVHPDDERYAK-----------------FVDK-- 240
Query: 272 GEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFKEKYEWAHRVILADFVTLEEGTG 331
EV+ + ++ + H+ +KEF GTG
Sbjct: 241 -------EVILPISKKAIKIIADKHV-------EKEF--------------------GTG 266
Query: 332 LVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTEG--KWKGIYVKEADPKIIEHLREKG 389
+V P H D+EVG ++ L S D++G E +++G+ EA KI+ L G
Sbjct: 267 VVKVTPAHDMNDYEVGLRHNLDFISVFDEKGILNEHCLEFQGLERLEAREKIVAKLESLG 326
Query: 390 YLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKDKIIKENDEKVT-----WYPD- 443
++ K E ++ +C+RC + + QWF VK +I +E+ EKV +YP+
Sbjct: 327 FIEKIEEYNNQIGYCYRCNNIVEPYISKQWF-----VKKEIAQESIEKVALGESKFYPNH 381
Query: 444 WVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVELAVAIEVNGER 503
W+ F+ ++D DW ISRQ +WG +P++ E +
Sbjct: 382 WIN-SFNAWMKDLRDWCISRQLWWGHQIPVYYCECSHEWA-------------------- 420
Query: 504 IELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWAS 563
H P K ++ ++ +DV+D WF SG+ + ++
Sbjct: 421 ---------------------SQHTPKTCP---KCQSQNFKQDEDVLDTWFSSGLWAMST 456
Query: 564 LGYPRNKELFEKLW---------PADFIVEGEDQVTKWFYSQQAASIVAFDTVPYRRVAM 614
LG+ +K+W P ++ G D + W S +P++ + +
Sbjct: 457 LGWGNENWGKDKIWSEKDLKDFYPNSLLITGFDILFFWVARMMFQSTNVLHQLPFKDIYL 516
Query: 615 HGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENLKFSWKGVEQVRR 674
H V DE+G KMSKSLGN+I P E ++ D RF + ++K S + QVR
Sbjct: 517 HALVKDEQGRKMSKSLGNVIDPNESIKEYSADILRFTLALLAIQGRDIKLSNDKLLQVRN 576
Query: 675 MLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISEVENGIESFYL 734
N ++N A Y+ L+ L L E K+I ++ + + +V ++++
Sbjct: 577 FTNKIYN----AKNYLLLNESKFEDLENITL-HSELAKYIYAKFQTCVKDVRENLDNYRF 631
Query: 735 TKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFDVLLRLLAPFTPY 794
A LY F +D W + L + + ++ L +F L+LL PF P+
Sbjct: 632 NDAANTLYKFFWDDFCDWGIELSKA----------EKSSVKELGSIFKEALKLLNPFMPF 681
Query: 795 IAEEIYQNLI-RPFTNVESVHMLDWPKVDEKAIDEELEREMEFIRRIVEAGSAARQRAKI 853
I+E +Y L S+ + +PK E+ D+ +E+ + I S R ++ I
Sbjct: 682 ISEYLYHKLSDTELKTSPSIMISKYPKFKEQ--DKNIEKIFSLL--IESIVSIRRAKSLI 737
Query: 854 KL-RYPVRRIIIETEDETVKKAVE 876
L + + I+ D+ +K ++
Sbjct: 738 DLGNSKIEKAYIKFNDKKIKDEIK 761
>pir||H81686 valyl-tRNA synthetase TC0576 [imported] - Chlamydia muridarum
(strain Nigg) >gi|7190615|gb|AAF39411.1| (AE002326)
valyl-tRNA synthetase [Chlamydia muridarum]
Length = 939
Score = 240 bits (606), Expect = 6e-62
Identities = 208/844 (24%), Positives = 347/844 (40%), Gaps = 144/844 (17%)
Query: 2 IKEPEF-REYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTA 60
+ E +F + YDPK E V FW + ++ + + P Y + PP V+G +H+G A
Sbjct: 1 MNEDQFPKAYDPKSSESGVYSFWERSGMF--IADANSKKPAYSIVMPPPNVTGILHMGHA 58
Query: 61 WNKIIKDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIK 120
++DM+IR++ M+G+ V PG D G+ + VE+ L K E F+K
Sbjct: 59 LVNTLQDMLIRYKRMKGFEVCWVPGTDHAGIATQTVVERHLRSSLGKR-RTDFSREEFLK 117
Query: 121 KCKEFALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRV 180
E+ + ++ Q + LG DW T+ E + K ++KG++ + +
Sbjct: 118 HVWEWKEKSQNVILSQLRQLGCSCDWSRQRFTMDPEANRAVKKAFKVLFDKGVIYRGYYL 177
Query: 181 LHWCPRCETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSA 240
++W P +TALA+ EV EY+ R+ Y+++PV E E++ + TT P TL + A++
Sbjct: 178 VNWDPILQTALADDEV--EYEEREGWLYYIRYPVVNSE-EFITVATTRPETLLGDTAIAV 234
Query: 241 HPDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMD 300
P+ E Y L IG K V+ F RE+
Sbjct: 235 SPE------------DERYSHL-----------IGAK--VIVPFVDREIP---------- 259
Query: 301 EYPRQKEFKEKYEWAHRVILADF-VTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLD 359
I+ DF V GTG V P H ++D+ G + LP+ + L
Sbjct: 260 ------------------IIGDFSVDASFGTGAVKITPAHDKDDYRTGMNHRLPMINILT 301
Query: 360 DQGKYTE--GKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATD 417
G+ E G + G+ + A II L G V+ + +R + +
Sbjct: 302 PTGEINENGGIFTGLAKESARENIITSLEALGLFVRKEAYSSRVGVSYRSGAIIEPYLSK 361
Query: 418 QWFLKISKVKDKIIK-ENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQS 476
QWF+ + ++ + + N +++ +P + V + DW ISRQ +WG +P+W +
Sbjct: 362 QWFVSVDSFRESLREFVNSKEINLFPPEFIRNYLTWVNNLKDWCISRQLWWGHRIPVWHN 421
Query: 477 EDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFII 536
+ E YV+ + V VA + PES+ Y D
Sbjct: 422 KHDEEYVICFDGDGVPEEVAQD--------PESW-------------------YQD---- 450
Query: 537 KVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQ 596
DV+D WF SG+ G+P K +P +V G D + W
Sbjct: 451 ----------PDVLDTWFSSGLWPLTCFGWPEESADLRKFYPTSVLVTGHDILFFWVTRM 500
Query: 597 QAASIVAFDTVPYRRVAMHGYVLDE----------------------------------K 622
DT P+ V +HG + + K
Sbjct: 501 VLMCSAMVDTKPFADVFLHGLIFGKSYKQYDDNGEWTYVSGDQKREYDKGKALPKNVVAK 560
Query: 623 GDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENLKFSWKGVEQVRRMLNILWNV 682
+K+SKS GN+I P E+++ G D RF + N E + ++ E+ + +N LWN
Sbjct: 561 WEKLSKSKGNVIDPIEMIDMYGADAVRFTLCSCANRGEQIDLDYRLFEEYKNFVNKLWNG 620
Query: 683 YVLASTYMS-LDNFDPRK-LNPDELPFREEDKWILSRVNSLISEVENGIESFYLTKATRA 740
++S L + D + +N D L ED +IL R N L++ +++ + K
Sbjct: 621 ARFIFGHISELTSRDLEEGVNKDLLGL--EDFYILDRFNELLALIDSHYNCYSFDKIAAL 678
Query: 741 LYNFVVEDLSRWYVRLIRKRLW-VEGEDPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEI 799
Y+F DL Y+ +I+ L+ +G D + L + +L +L P PYI E +
Sbjct: 679 AYDFFKNDLCSTYLEIIKPTLFGKQGNDEQRATKRKLLATLLVNILGVLHPIVPYITETL 738
Query: 800 YQNL 803
+Q +
Sbjct: 739 FQKI 742
>sp|O84304|SYV_CHLTR VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|7437659|pir||H71532 valine--tRNA ligase (EC 6.1.1.9)
- Chlamydia trachomatis (serotype D, strain UW3/Cx)
>gi|3328717|gb|AAC67895.1| (AE001302) Valyl tRNA
Synthetase [Chlamydia trachomatis]
Length = 939
Score = 235 bits (592), Expect = 3e-60
Identities = 222/927 (23%), Positives = 372/927 (39%), Gaps = 164/927 (17%)
Query: 2 IKEPEF-REYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTA 60
+ E +F + YDPK E V FW + ++ V + P Y + PP V+G +H+G A
Sbjct: 1 MNEDQFPKAYDPKSSETGVYSFWERSGMF--VANASSEKPAYSIVMPPPNVTGILHMGHA 58
Query: 61 WNKIIKDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIK 120
++D +IR++ MQG+ V PG D G+ + VE+ L K+ + E F+K
Sbjct: 59 LVNTLQDTLIRYKRMQGFEVCWVPGTDHAGIATQTVVERHLKASLGKQRTD-FSREEFLK 117
Query: 121 KCKEFALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRV 180
++ + ++ Q + LG DW T+ + K ++KG++ + +
Sbjct: 118 HVWDWKEKSQNVILSQLRQLGCSCDWSRQRFTMDPGANRAVKKAFKILFDKGVIYRGYYL 177
Query: 181 LHWCPRCETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSA 240
++W P +TALA+ EV EY+ R Y+++ V E E++ + TT P TL + A++
Sbjct: 178 VNWDPILQTALADDEV--EYEERDGWLYYIRYQVVNSE-EFITVATTRPETLLGDTAIAV 234
Query: 241 HPDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMD 300
P+ + R + I AK VV F RE+
Sbjct: 235 SPE----------DLRYSHLIGAK---------------VVVPFVNREIP---------- 259
Query: 301 EYPRQKEFKEKYEWAHRVILADF-VTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLD 359
I+ DF V GTG V P H ++D++ G + LP+ + L
Sbjct: 260 ------------------IIGDFSVDASFGTGAVKITPAHDKDDYKTGMNHQLPMINILT 301
Query: 360 DQGKYTE--GKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATD 417
G+ E G + G+ + A II L G VK + +R + +
Sbjct: 302 PTGEINENGGIFTGLSREVARENIITSLEALGLFVKKEAYSSRVGVSYRSGAIIEPYLSK 361
Query: 418 QWFLKISKVKDKIIK-ENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQS 476
QWF+ + +D + N E++ +P + V + DW ISRQ +WG +P+W +
Sbjct: 362 QWFVSVDSFRDSLRGFVNSEEIRIFPPEFVRNYLTWVNNLKDWCISRQLWWGHRIPVWHN 421
Query: 477 EDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFII 536
+ ++E + + + GPE++ R
Sbjct: 422 K--------------------------------HDENVICFDGEGGPEEVMR-------- 441
Query: 537 KVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKEL-FEKLWPADFIVEGEDQVTKWFYS 595
+ + + DV+D WF SG+ G+P L +K +P +V G D + W
Sbjct: 442 --DPESWYQDPDVLDTWFSSGLWPLTCFGWPDENSLDLKKFYPTAVLVTGHDILFFWVTR 499
Query: 596 QQAASIVAFDTVPYRRVAMHGYVL-------DEKGD------------------------ 624
DT P+ V +HG + DEKG+
Sbjct: 500 MVLMCSAMVDTEPFSDVFLHGLIFGKSYREYDEKGEWFYVSGERKRDYDKGKALPKNVVA 559
Query: 625 ---KMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENLKFSWKGVEQVRRMLNILWN 681
K+SKS GN+I P E++E G D R + N E + + E+ + +N LWN
Sbjct: 560 KWEKLSKSKGNVIDPIEMIEAYGADAVRLTLCSCANRGEQIDLDYHLFEEYKNFINKLWN 619
Query: 682 VYVLASTYMS-LDNFDPRK-LNPDELPFREEDKWILSRVNSLISEVENGIESFYLTKATR 739
++S L + D + +N D L ED +IL R N L+ ++ + K
Sbjct: 620 GARFIFGHISELTSRDLEEGVNQDLLGL--EDFYILDRFNELLDLIDGHYNCYSFDKIAS 677
Query: 740 ALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFDV-LLRLLAPFTPYIAEE 798
Y+F DL Y+ +I+ L+ + + + A L + +L +L P PYI E
Sbjct: 678 LAYDFFKNDLCSTYLEIIKPTLFGKQDSDQQRATKRKLLATLLINILGVLHPIVPYITET 737
Query: 799 IYQNLIRPFTNVE----------SVHML--------DWPKVDEKAIDEELEREMEFIRRI 840
++Q L VE +V ML ++PK A + L R+
Sbjct: 738 LFQKLKATLGTVENGKGDSVTGHAVSMLRSEACMVAEYPKPIHVAFPQGLRESFGIAERL 797
Query: 841 VEAGSAARQRAKIKLRYPVRRIIIETE 867
V R ++ R P++ +I +E
Sbjct: 798 VYTIRNIRGEMQLDPREPLQAFVISSE 824
>gb|AAA24657.1| (J03497) valyl tRNA synthetase [Escherichia coli]
Length = 951
Score = 232 bits (585), Expect = 2e-59
Identities = 220/938 (23%), Positives = 386/938 (40%), Gaps = 196/938 (20%)
Query: 8 REYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKD 67
+ Y+P+ +E+ + + W + ++ + ++ + + PP V+G++H+G A+ + I D
Sbjct: 3 KTYNPQDIEQPLYEHWEKQGYFKPNGDESQES--FCIMIPPPNVTGSLHMGHAFQQTIMD 60
Query: 68 MIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFAL 127
+IR++ MQG N Q G D G+ ++ VE+ + + K + G E FI K E+
Sbjct: 61 TMIRYQRMQGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTRHD-YGAEAFIDKIWEWKA 119
Query: 128 NNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRC 187
+ +T Q + LG +DW+ T+ + R +++ L+ + KR+++W P+
Sbjct: 120 ESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRLYKEDLIYRGKRLVNWDPKL 179
Query: 188 ETALAEHEVRGEYKLRKDPSIYVKFPV-------EGKENEYLLIWTTTPWTLPANLAVSA 240
TA+++ EV E + K ++++P+ +GK+ YL++ TT P TL
Sbjct: 180 RTAISDLEV--ENRESKGSMWHIRYPLADGAKTADGKD--YLVVATTRPETL-------- 227
Query: 241 HPDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMD 300
LG+ GV +
Sbjct: 228 ------------------------------LGDTGVA--------------------VNP 237
Query: 301 EYPRQKEFKEKYEWAHRV-----ILAD-FVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPV 354
E PR K+ KY V I+ D +E+GTG V P H D+EVG+++ LP+
Sbjct: 238 EDPRYKDLIGKYVILPLVNRRIPIVGDEHADMEKGTGCVKITPAHDFNDYEVGKRHALPM 297
Query: 355 YSPLDDQGKY--------TEGKWKGIYVKE--ADPKIIEHLREKGYLVKA----GEIEHK 400
+ L G T+G +Y E A+ + +E + +V A G +E
Sbjct: 298 INILTFDGDIRESAQVFDTKGNESDVYSSEIPAEFQKLERFAARKAVVAAVDALGLLEEI 357
Query: 401 YPHCW------RCKTPLIFRATDQWFLKISKVKDKIIK--ENDEKVTWYPDWVKIRFDNG 452
PH R + TDQW+++ + ++ EN + + + P + + +
Sbjct: 358 KPHDLTVPYGDRGGVVIEPMLTDQWYVRADVLAKPAVEAVENGD-IQFVPKQYENMYFSW 416
Query: 453 VRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEE 512
+RD DW ISRQ +WG +P W E G +YV + E+ +
Sbjct: 417 MRDIQDWCISRQLWWGHRIPAWYDEAGNVYVGRNEDEVRK-------------------- 456
Query: 513 KLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKEL 572
E LG + + +R+ +DV+D WF S + ++++LG+P N +
Sbjct: 457 -----ENNLGADVV----------------LRQDEDVLDTWFSSALWTFSTLGWPENTDA 495
Query: 573 FEKLWPADFIVEGEDQVTKWFYSQQAASIVAF-------DTVPYRRVAMHGYVLDEKGDK 625
+ P +V G D + W ++ + F VP+ V M G + D++G K
Sbjct: 496 LRQFHPTSVMVSGFDIIFFWI-ARMIMMTMHFIKDENGKPQVPFHTVYMTGLIRDDEGQK 554
Query: 626 MSKSLGNIIRPEEVV-------------------------------------ERAGRDTF 648
MSKS GN+I P ++V E G D
Sbjct: 555 MSKSKGNVIDPLDMVDGISLPELLEKRTGNMMQPQLADKIRKRTEKQFPNGIEPHGTDAL 614
Query: 649 RFYMLWATNPWENLKFSWKGVEQVRRMLNILWNV--YVLASTYMSLDNFDPRKLNPDELP 706
RF + + ++ + K +E R N LWN +VL +T F N E+
Sbjct: 615 RFTLAALASTGRDINWDMKRLEGYRNFCNKLWNASRFVLMNTEGQDCGF-----NGGEMT 669
Query: 707 FREEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGE 766
D+WIL+ N I ++SF A LY F WY+ L K + G
Sbjct: 670 LSLADRWILAEFNQTIKAYREALDSFRFDIAAGILYEFTWNQFCDWYLEL-TKPVMNGGT 728
Query: 767 DPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNL-IRPFTNVESVHMLDWPKVDEKA 825
+ + +TL V + LLRL P P+I E I+Q + + +++ + +P+ D
Sbjct: 729 EAELRGTRHTLVTVLEGLLRLAHPIIPFITETIWQRVKVLCGITADTIMLQPFPQYDASQ 788
Query: 826 IDEELEREMEFIRRIVEAGSAARQRAKIKLRYPVRRII 863
+DE + E++++ + A R I P+ ++
Sbjct: 789 VDEAALADTEWLKQAIVAVRNIRAEMNIAPGKPLELLL 826
>sp|P07118|SYV_ECOLI VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|7428469|pir||SYECVT valine--tRNA ligase (EC 6.1.1.9)
- Escherichia coli (strain K-12)
>gi|1790708|gb|AAC77215.1| (AE000496) valine tRNA
synthetase [Escherichia coli K12]
Length = 951
Score = 231 bits (582), Expect = 4e-59
Identities = 220/938 (23%), Positives = 386/938 (40%), Gaps = 196/938 (20%)
Query: 8 REYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKD 67
+ Y+P+ +E+ + + W + ++ + ++ + + PP V+G++H+G A+ + I D
Sbjct: 3 KTYNPQDIEQPLYEHWEKQGYFKPNGDESQES--FCIMIPPPNVTGSLHMGHAFQQTIMD 60
Query: 68 MIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFAL 127
+IR++ MQG N Q G D G+ ++ VE+ + + K + G E FI K E+
Sbjct: 61 TMIRYQRMQGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTRHD-YGREAFIDKIWEWKA 119
Query: 128 NNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRC 187
+ +T Q + LG +DW+ T+ + R +++ L+ + KR+++W P+
Sbjct: 120 ESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRLYKEDLIYRGKRLVNWDPKL 179
Query: 188 ETALAEHEVRGEYKLRKDPSIYVKFPV-------EGKENEYLLIWTTTPWTLPANLAVSA 240
TA+++ EV E + K ++++P+ +GK+ YL++ TT P TL
Sbjct: 180 RTAISDLEV--ENRESKGSMWHIRYPLADGAKTADGKD--YLVVATTRPETL-------- 227
Query: 241 HPDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMD 300
LG+ GV +
Sbjct: 228 ------------------------------LGDTGVA--------------------VNP 237
Query: 301 EYPRQKEFKEKYEWAHRV-----ILAD-FVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPV 354
E PR K+ KY V I+ D +E+GTG V P H D+EVG+++ LP+
Sbjct: 238 EDPRYKDLIGKYVILPLVNRRIPIVGDEHADMEKGTGCVKITPAHDFNDYEVGKRHALPM 297
Query: 355 YSPLDDQGKY--------TEGKWKGIYVKE--ADPKIIEHLREKGYLVKA----GEIEHK 400
+ L G T+G +Y E A+ + +E + +V A G +E
Sbjct: 298 INILTFDGDIRESAQVFDTKGNESDVYSSEIPAEFQKLERFAARKAVVAAVDALGLLEEI 357
Query: 401 YPHCW------RCKTPLIFRATDQWFLKISKVKDKIIK--ENDEKVTWYPDWVKIRFDNG 452
PH R + TDQW+++ + ++ EN + + + P + + +
Sbjct: 358 KPHDLTVPYGDRGGVVIEPMLTDQWYVRADVLAKPAVEAVENGD-IQFVPKQYENMYFSW 416
Query: 453 VRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEE 512
+RD DW ISRQ +WG +P W E G +YV + E+ +
Sbjct: 417 MRDIQDWCISRQLWWGHRIPAWYDEAGNVYVGRNEDEVRK-------------------- 456
Query: 513 KLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKEL 572
E LG + + +R+ +DV+D WF S + ++++LG+P N +
Sbjct: 457 -----ENNLGADVV----------------LRQDEDVLDTWFSSALWTFSTLGWPENTDA 495
Query: 573 FEKLWPADFIVEGEDQVTKWFYSQQAASIVAF-------DTVPYRRVAMHGYVLDEKGDK 625
+ P +V G D + W ++ + F VP+ V M G + D++G K
Sbjct: 496 LRQFHPTSVMVSGFDIIFFWI-ARMIMMTMHFIKDENGKPQVPFHTVYMTGLIRDDEGQK 554
Query: 626 MSKSLGNIIRPEEVV-------------------------------------ERAGRDTF 648
MSKS GN+I P ++V E G D
Sbjct: 555 MSKSKGNVIDPLDMVDGISLPELLEKRTGNMMQPQLADKIRKRTEKQFPNGIEPHGTDAL 614
Query: 649 RFYMLWATNPWENLKFSWKGVEQVRRMLNILWNV--YVLASTYMSLDNFDPRKLNPDELP 706
RF + + ++ + K +E R N LWN +VL +T F N E+
Sbjct: 615 RFTLAALASTGRDINWDMKRLEGYRNFCNKLWNASRFVLMNTEGQDCGF-----NGGEMT 669
Query: 707 FREEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGE 766
D+WIL+ N I ++SF A LY F WY+ L K + G
Sbjct: 670 LSLADRWILAEFNQTIKAYREALDSFRFDIAAGILYEFTWNQFCDWYLEL-TKPVMNGGT 728
Query: 767 DPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNL-IRPFTNVESVHMLDWPKVDEKA 825
+ + +TL V + LLRL P P+I E I+Q + + +++ + +P+ D
Sbjct: 729 EAELRGTRHTLVTVLEGLLRLAHPIIPFITETIWQRVKVLCGITADTIMLQPFPQYDASQ 788
Query: 826 IDEELEREMEFIRRIVEAGSAARQRAKIKLRYPVRRII 863
+DE + E++++ + A R I P+ ++
Sbjct: 789 VDEAALADTEWLKQAIVAVRNIRAEMNIAPGKPLELLL 826
>emb|CAA29322.1| (X05891) valyl-tRNA synthetase [Escherichia coli]
Length = 951
Score = 229 bits (579), Expect = 9e-59
Identities = 219/938 (23%), Positives = 386/938 (40%), Gaps = 196/938 (20%)
Query: 8 REYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKD 67
+ Y+P+ +E+ + + W + ++ + ++ + + PP V+G++H+G A+ + I D
Sbjct: 3 KTYNPQDIEQPLYEHWEKQGYFKPNGDESQES--FCIMIPPPNVTGSLHMGHAFQQTIMD 60
Query: 68 MIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFAL 127
+IR++ MQG N Q G D G+ ++ VE+ + + K + G E FI K E+
Sbjct: 61 TMIRYQRMQGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTRHD-YGREAFIDKIWEWKA 119
Query: 128 NNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRC 187
+ +T Q + LG +DW+ T+ + R +++ L+ + KR+++W P+
Sbjct: 120 ESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRLYKEDLIYRGKRLVNWDPKL 179
Query: 188 ETALAEHEVRGEYKLRKDPSIYVKFPV-------EGKENEYLLIWTTTPWTLPANLAVSA 240
TA+++ EV E + K ++++P+ +GK+ YL++ TT P TL
Sbjct: 180 RTAISDLEV--ENRESKGSMWHIRYPLADGAKTADGKD--YLVVATTRPETL-------- 227
Query: 241 HPDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMD 300
LG+ GV +
Sbjct: 228 ------------------------------LGDTGVA--------------------VNP 237
Query: 301 EYPRQKEFKEKYEWAHRV-----ILAD-FVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPV 354
E PR K+ KY V I+ D +E+GTG V P H D+EVG+++ LP+
Sbjct: 238 EDPRYKDLIGKYVILPLVNRRIPIVGDEHADMEKGTGCVKITPAHDFNDYEVGKRHALPM 297
Query: 355 YSPLDDQGKY--------TEGKWKGIYVKE--ADPKIIEHLREKGYLVKA----GEIEHK 400
+ L G T+G +Y E A+ + +E + +V A G +E
Sbjct: 298 INILTFDGDIRESAQVFDTKGNESDVYSSEIPAEFQKLERFAARKAVVAAVDALGLLEEI 357
Query: 401 YPHCW------RCKTPLIFRATDQWFLKISKVKDKIIK--ENDEKVTWYPDWVKIRFDNG 452
PH R + TDQW+++ + ++ EN + + + P + + +
Sbjct: 358 KPHDLTVPYGDRGGVVIEPMLTDQWYVRADVLAKPAVEAVENGD-IQFVPKQYENMYFSW 416
Query: 453 VRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEE 512
+RD DW ISRQ +WG +P W E G +YV + E+ +
Sbjct: 417 MRDIQDWCISRQLWWGHRIPAWYDEAGNVYVGRNEDEVRK-------------------- 456
Query: 513 KLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKEL 572
E LG + + +R+ +DV+D WF S + ++++LG+P N +
Sbjct: 457 -----ENNLGADVV----------------LRQDEDVLDTWFSSALWTFSTLGWPENTDA 495
Query: 573 FEKLWPADFIVEGEDQVTKWFYSQQAASIVAF-------DTVPYRRVAMHGYVLDEKGDK 625
+ P +V G D + W ++ + F VP+ V M G + D++G K
Sbjct: 496 LRQFHPTSVMVSGFDIIFFWI-ARMIMMTMHFIKDENGKPQVPFHTVYMTGLIRDDEGQK 554
Query: 626 MSKSLGNIIRPEEVV-------------------------------------ERAGRDTF 648
MSKS GN+I P ++V E G D
Sbjct: 555 MSKSKGNVIDPLDMVDGISLPELLEKRTGNMMQPQLADKIRKRTEKQFPNGIEPHGTDAL 614
Query: 649 RFYMLWATNPWENLKFSWKGVEQVRRMLNILWNV--YVLASTYMSLDNFDPRKLNPDELP 706
RF + + ++ + K +E R N LWN +VL +T F N E+
Sbjct: 615 RFTLAALASTGRDINWDMKRLEGYRNFCNKLWNASRFVLMNTEGQDCGF-----NGGEMT 669
Query: 707 FREEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGE 766
D+WIL+ N I +++F A LY F WY+ L K + G
Sbjct: 670 LSLADRWILAEFNQTIKAYREALDTFRFDIAAGILYEFTWNQFCDWYLEL-TKPVMNGGT 728
Query: 767 DPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNL-IRPFTNVESVHMLDWPKVDEKA 825
+ + +TL V + LLRL P P+I E I+Q + + +++ + +P+ D
Sbjct: 729 EAELRGTRHTLVTVLEGLLRLAHPIIPFITETIWQRVKVLCGITADTIMLQPFPQYDASQ 788
Query: 826 IDEELEREMEFIRRIVEAGSAARQRAKIKLRYPVRRII 863
+DE + E++++ + A R I P+ ++
Sbjct: 789 VDEAALADTEWLKQAIVAVRNIRAEMNIAPGKPLELLL 826
>gb|AAA97155.1| (U14003) valyl-tRNA synthetase [Escherichia coli]
Length = 951
Score = 229 bits (578), Expect = 1e-58
Identities = 219/938 (23%), Positives = 385/938 (40%), Gaps = 196/938 (20%)
Query: 8 REYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKD 67
+ Y+P+ +E+ + + W + ++ + ++ + + PP V+G++H+G A+ + I D
Sbjct: 3 KTYNPQDIEQPLYEHWEKQGYFKPNGDESQES--FCIMIPPPNVTGSLHMGHAFQQTIMD 60
Query: 68 MIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFAL 127
+IR++ MQG N Q G D G+ ++ VE+ + + K + G E FI K E+
Sbjct: 61 TMIRYQRMQGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTRHD-YGREAFIDKIWEWKA 119
Query: 128 NNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRC 187
+ +T Q + LG +DW+ T+ + R +++ L+ + KR+++W P+
Sbjct: 120 ESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRLYKEDLIYRGKRLVNWDPKL 179
Query: 188 ETALAEHEVRGEYKLRKDPSIYVKFPV-------EGKENEYLLIWTTTPWTLPANLAVSA 240
TA+++ EV E + K ++++P+ +GK+ YL++ TT P TL
Sbjct: 180 RTAISDLEV--ENRESKGSMWHIRYPLADGAKTADGKD--YLVVATTRPETL-------- 227
Query: 241 HPDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMD 300
LG+ GV +
Sbjct: 228 ------------------------------LGDTGVA--------------------VNP 237
Query: 301 EYPRQKEFKEKYEWAHRV-----ILAD-FVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPV 354
E PR K+ KY V I+ D +E+GTG V P H D+EVG+++ LP+
Sbjct: 238 EDPRYKDLIGKYVILPLVNRRIPIVGDEHADMEKGTGCVKITPAHDFNDYEVGKRHALPM 297
Query: 355 YSPLDDQGKY--------TEGKWKGIYVKE--ADPKIIEHLREKGYLVKA----GEIEHK 400
+ L G T+G +Y E A+ + +E + +V A G +E
Sbjct: 298 INILTFDGDIRESAQVFDTKGNESDVYSSEIPAEFQKLERFAARKAVVAAVDALGLLEEI 357
Query: 401 YPHCW------RCKTPLIFRATDQWFLKISKVKDKIIK--ENDEKVTWYPDWVKIRFDNG 452
PH R + TDQW+++ + ++ EN + + + P + + +
Sbjct: 358 KPHDLTVPYGDRGGVVIEPMLTDQWYVRADVLAKPAVEAVENGD-IQFVPKQYENMYFSW 416
Query: 453 VRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEE 512
+RD DW ISRQ +WG +P W E G +YV + E+ +
Sbjct: 417 MRDIQDWCISRQLWWGHRIPAWYDEAGNVYVGRNEDEVRK-------------------- 456
Query: 513 KLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKEL 572
E LG + + +R+ +DV+D WF S + ++++LG+P N +
Sbjct: 457 -----ENNLGADVV----------------LRQDEDVLDTWFSSALWTFSTLGWPENTDA 495
Query: 573 FEKLWPADFIVEGEDQVTKWFYSQQAASIVAF-------DTVPYRRVAMHGYVLDEKGDK 625
+ P +V G D + W ++ + F VP+ V M G + D++G K
Sbjct: 496 LRQFHPTSVMVSGFDIIFFWI-ARMIMMTMHFIKDENGKPQVPFHTVYMTGLIRDDEGQK 554
Query: 626 MSKSLGNIIRPEEVV-------------------------------------ERAGRDTF 648
MSKS GN+I P ++V E G D
Sbjct: 555 MSKSKGNVIDPLDMVDGISLPELLEKRTGNMMQPQLADKIRKRTEKQFPNGIEPHGTDAL 614
Query: 649 RFYMLWATNPWENLKFSWKGVEQVRRMLNILWNV--YVLASTYMSLDNFDPRKLNPDELP 706
RF + + ++ + K +E R N LWN +VL +T F N E+
Sbjct: 615 RFTLAALASTGRDINWDMKRLEGYRNFCNKLWNASRFVLMNTEGQDCGF-----NGGEMT 669
Query: 707 FREEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGE 766
D+WIL+ N I ++ F A LY F WY+ L K + G
Sbjct: 670 LSLADRWILAEFNQTIKAYREALDXFRFDIAAGILYEFTWNQFCDWYLEL-TKPVMNGGT 728
Query: 767 DPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNL-IRPFTNVESVHMLDWPKVDEKA 825
+ + +TL V + LLRL P P+I E I+Q + + +++ + +P+ D
Sbjct: 729 EAELRGTRHTLVTVLEGLLRLAHPIIPFITETIWQRVKVLCGITADTIMLQPFPQYDASQ 788
Query: 826 IDEELEREMEFIRRIVEAGSAARQRAKIKLRYPVRRII 863
+DE + E++++ + A R I P+ ++
Sbjct: 789 VDEAALADTEWLKQAIVAVRNIRAEMNIAPGKPLELLL 826
>sp|O51680|SYV_BORBU VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|7437647|pir||A70192 valine--tRNA ligase (EC 6.1.1.9)
valS - Lyme disease spirochete
>gi|2688666|gb|AAC67078.1| (AE001173) valyl-tRNA
synthetase (valS) [Borrelia burgdorferi]
Length = 875
Score = 227 bits (573), Expect = 5e-58
Identities = 199/839 (23%), Positives = 369/839 (43%), Gaps = 131/839 (15%)
Query: 9 EYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDM 68
+YDPK E+++ W +N ++ L + K+ + PP V+G +H+G A N +++D+
Sbjct: 8 KYDPKAFEDEIYTKWLKNNVFLPDNSLFE---KFSMVAPPPNVTGVLHMGHALNFVLQDV 64
Query: 69 IIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGL--KTKKEIEEKIGVENFIKKCKEFA 126
++R++ M+ +N G D G+ + E+ L K+K + E E +++ +
Sbjct: 65 LVRYKRMKRHNTLWLFGTDHAGIATQAVFERHLKKIGKSKDDFER----EELVQEIFKLK 120
Query: 127 LNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPR 186
+ I+ Q LG D T+ ++ K + KGL+ + + +++ P
Sbjct: 121 DRHRGIIVNQINKLGASYDHSRERFTLDENLCKAVNKVFKDLYFKGLIYRGEYLVNLDPG 180
Query: 187 CETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDY 246
+ +++ E+ EYK +VK+ ++ + ++ + TT P T+ + A++ +P+
Sbjct: 181 SGSVVSDEEI--EYKEVDGKLYFVKYFIDN--SSFIEVATTRPETMFGDTAIAVNPN--- 233
Query: 247 VKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQK 306
E Y K+LV K EV ++++
Sbjct: 234 ---------DERY----KSLVGK---------EVTIPLTTKKIK---------------- 255
Query: 307 EFKEKYEWAHRVILADF-VTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYT 365
++ADF V GTG + P H DFE+ +++ + + L GK
Sbjct: 256 ------------VIADFYVDSAFGTGALKVTPAHDPNDFEISKRHNISKVNILTQDGKLN 303
Query: 366 EG---KWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLK 422
+ +++G+ K+A KI L EKG+L + + + HC+R + + QWF++
Sbjct: 304 KNVPLQYQGLSAKDARFKIETELMEKGFLQDVKKHKQQVGHCYRSGEVIEPYLSTQWFVR 363
Query: 423 ISKVKDKIIK--ENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGE 480
+ + DK +K EN E + +YP + + + + DW ISRQ WG +P+W + D
Sbjct: 364 MKPLADKALKALENGE-LKFYPKKWENTYKYWLSNIRDWCISRQLVWGHRIPVWYNVDTS 422
Query: 481 IYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNG 540
+V + S +EK G
Sbjct: 423 ELIVS-------------------DTDPSLDEKNM------------------------G 439
Query: 541 KDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAAS 600
K + DV+D WF S + ++SLG+P F+ +P + ++ D + W A
Sbjct: 440 KRFVQDPDVLDTWFSSWLWPFSSLGWPNVDVDFKNYYPTNTLITAYDIIFFWVARMVMAG 499
Query: 601 IVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWE 660
+ VP++ V + + D++G KMSKSLGN I P +++ G D+ RF + + + +
Sbjct: 500 LEFTGQVPFKDVYITPLLRDKQGKKMSKSLGNGIDPLDIINEYGSDSLRFTLSFLSVQGQ 559
Query: 661 NLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNS 720
+L K + N ++N AS ++ L+ + + LN +L F + DKW+L+ +NS
Sbjct: 560 DLNIDAKDFMFGAKFANKVFN----ASKFILLNLKNRKILN--DLKFNDIDKWLLTSLNS 613
Query: 721 LISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKV 780
I VE+ ++ +A++ +Y F D WY+ + + L E D +A L+ +
Sbjct: 614 TILGVESSFANYKYNEASKFVYEFFWNDFCDWYIEISKIDLNNENVDIQNMAISKLLFFL 673
Query: 781 FDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHML-DWPKVDEKAIDEELEREMEFIR 838
LL +L PF P++ E+IY F E + L ++P D I + E E +
Sbjct: 674 KKSLL-ILHPFIPFVTEKIYSE----FAEKEDILALNEYPNFD---IANNFQEEFEIFK 724
>pir||C72565 probable valyl-tRNA synthetase APE1805 - Aeropyrum pernix (strain
K1) >gi|5105495|dbj|BAA80808.1| (AP000062) 889aa long
hypothetical valyl-tRNA synthetase [Aeropyrum pernix]
Length = 889
Score = 227 bits (573), Expect = 5e-58
Identities = 217/884 (24%), Positives = 365/884 (40%), Gaps = 128/884 (14%)
Query: 16 EEKVEKFWSENEIYRKVKELRKDGPKYYFL--DGPPYVSGAIHLGTAWNKIIKDMIIRFR 73
EEK+ W ++++ L D P+ + PPY SG H+G A + DMI R+
Sbjct: 85 EEKLLSLWDAEDLHKST--LDPDDPREIVVIDTPPPYPSGKWHVGGAAHYTQIDMIARYF 142
Query: 74 TMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIM 133
++GYNV D +GLP+EV+VE+ G+ + G E F+ C EF +
Sbjct: 143 RLKGYNVVAPFYADRNGLPVEVQVEKTYGVVAHEMARTTEGRERFLALCSEFLDKVESEI 202
Query: 134 TEQFKMLGIWMDW-----DNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCE 188
+ ++ LG D+ D+P Y T W +GL+ + +R + WCPRC+
Sbjct: 203 VQLWRRLGCGFDYWREGTDSP------RYRSMTQATFIDLWRRGLIYEAERPVRWCPRCK 256
Query: 189 TALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVK 248
T LAE E+ E+K +D YVK+ +E ++ L++ TT P L A++ HP+ + K
Sbjct: 257 TTLAEAEI--EHKEDEDFIYYVKYRLE-EDGRDLVVATTRPELLAGCAALAYHPEDERYK 313
Query: 249 VKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEF 308
+ K + + G + ++VE
Sbjct: 314 -----------GLAGKTAIAPLYGH---RVKIVE-------------------------- 333
Query: 309 KEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTE-- 366
H + DF GTGL+ EED + + L +D+ G E
Sbjct: 334 -------HPAVKKDF-----GTGLMMICSYGDEEDVRLFLELDLKPKVLIDENGVMNENA 381
Query: 367 GKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKV 426
G G+ VKEA +I E L +G LVK I H P CWRCKTPL + FL+
Sbjct: 382 GPIAGLPVKEARRRIAEILEREGLLVKKERIVHSVPVCWRCKTPLQIIHRRELFLRQLDF 441
Query: 427 KDKIIKENDEKVTWYPDWVKIRFDNGVRD-SGDWVISRQRYWGIPLPIWQSEDGEIYVVG 485
KD +K+ K+ + P+ + + + + DW ISR+R++G +P+W E
Sbjct: 442 KD-AVKQAAAKMDFKPEMHRKKLYDWIDSIKMDWPISRERFYGTEIPLWTCE-------- 492
Query: 486 SWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRR 545
+ + + P Y P P+ + ++
Sbjct: 493 ------------KCGAKLVPEPGRYYR----------PWAEEPPWDSCPRCGAPRRYLKG 530
Query: 546 VKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVAFD 605
V D WFDS I+ + +K +E+ +G+D + W Y +
Sbjct: 531 ETRVFDTWFDSSISPLYVTRWMWDKRFYERASRNVLRPQGQDIIRTWLYYSILRVLQLTG 590
Query: 606 TVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENLKFS 665
+R V + G LD KG M KSLGN+I PE ++ + G D FRF+ A + +F
Sbjct: 591 KPAFRWVRITGLGLDPKGRPMHKSLGNVIDPEPIIAKYGGDAFRFWAAIAAKLGYDYRFD 650
Query: 666 WKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISEV 725
V+ R LWN+ S++ PR E DK L+ + +
Sbjct: 651 ENKVKTGRNFATKLWNLARFVSSF-------PRPEGSPLEKATEVDKAFLALADEYLEAA 703
Query: 726 ENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEG---EDPDKLAAYYTLWKVFD 782
+ + + +Y + + YV L+++R + ++ AA+ TL ++
Sbjct: 704 DKAYGELDVYEPANLIYELAWDIFASHYVELVKERSYNRSGLFTREEQEAAWATLHELLR 763
Query: 783 VLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREMEFIRRIVE 842
+L L+P P++ + I++ L SVH WP + E RE+ R++
Sbjct: 764 RILVALSPIMPFVTDAIHRRLYG-----SSVHRQRWP---DPLFTPEERRELAGKARLIV 815
Query: 843 AGSAA----RQRAKIKLRYPVR--RIIIETEDETVKKAVERLNR 880
+ + A ++ KL P+ +++ + E+ ++ +E L++
Sbjct: 816 SVNKAVWNLKRSMGKKLYEPLDTVEVLVPSGIESARRDLEALHK 859
>sp|P93736|SYV_ARATH VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|1890130|gb|AAB49704.1| (U89986) valyl tRNA
synthetase [Arabidopsis thaliana]
Length = 1107
Score = 226 bits (571), Expect = 8e-58
Identities = 211/908 (23%), Positives = 375/908 (41%), Gaps = 156/908 (17%)
Query: 8 REYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKD 67
++Y P +E+ +W ++++++ + + P + + PP V+GA+H+G A I+D
Sbjct: 138 KQYSPATVEKSWYAWWEKSDLFKA--DAKSSKPPFVIVLPPPNVTGALHIGHALTSAIED 195
Query: 68 MIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFAL 127
IIR++ M GYN PG D G+ +V VE+ + ++ + +G E F+K+ ++
Sbjct: 196 TIIRWKRMSGYNALWVPGVDHAGIATQVVVEKKI-MRDRGMTRHDVGREEFVKEVWKWKN 254
Query: 128 NNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRC 187
+ Q + LG +DW T+ + ++ R +++GL+ +D R+++W
Sbjct: 255 QYGGTILTQLRRLGASLDWSRECFTMDEQRSKAVTEAFVRLYKEGLIYRDIRLVNWDCIL 314
Query: 188 ETALAEHEVR----GEYKLRKDP--------SIYVKFPVEGKENEYLLIWTTTPWTLPAN 235
TA+++ EV E L K P + F +E +++ TT T+ +
Sbjct: 315 RTAISDVEVEYIDIKEKTLLKVPGYEKPVEFGLLTSFAYPLEELGRVIVATTRVETMLGD 374
Query: 236 LAVSAHPD---YDYVKVKV---EFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGREL 289
A++ HPD Y ++ K FNGR+ I LVD G VK
Sbjct: 375 TAIAIHPDDARYKHLHGKFAVHPFNGRKLPIICDGILVDPNFGTGCVK------------ 422
Query: 290 EGLRYVHILMDEYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQK 349
I P E ++++ +F+ + G ++T +G DF
Sbjct: 423 -------ITPAHDPNDCEVGKRHK-------LEFINIFTDDGKINT---NGGSDFA---- 461
Query: 350 YGLPVYSPLDDQGKYTEGKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKT 409
G+P ++ A ++E L+++G A E + C R
Sbjct: 462 -GMPRFA--------------------AREAVVEALQKQGLYRGAKNNEMRLGLCSRTND 500
Query: 410 PLIFRATDQWFLKIS----KVKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQR 465
+ QW++ S + D I + ++K+ + P + + + DW ISRQ
Sbjct: 501 VIEPMIKPQWYVNCSMXGKEALDVAITDENKKLEFVPKQYTAEWRRWLENIRDWCISRQL 560
Query: 466 YWGIPLPIWQS--EDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGP 523
+WG +P W + E+ ++ VG++ + +A R E E K + +K
Sbjct: 561 WWGHRIPAWYATLEEDQLKEVGAYSDHWVVA--------RTEDDAREEAAQKFLGKKF-- 610
Query: 524 EDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIV 583
++ R DV+D WF SG+ + LG+P + F+ +P +
Sbjct: 611 ------------------ELTRDPDVLDTWFSSGLFPLSVLGWPDVTDDFKAFYPTSVLE 652
Query: 584 EGEDQVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVE-- 641
G D + W + VP+ +V H + D G KMSKSLGN+I P EV+
Sbjct: 653 TGHDILFFWVARMVMMGMKLGGEVPFSKVYFHPMIRDAHGRKMSKSLGNVIDPLEVINGV 712
Query: 642 -----------------------------------RAGRDTFRFYMLWATNPWENLKFSW 666
G D RF ++ T + +
Sbjct: 713 TLGGLHKRLEEGNLDPKEVIVAKEGQVKDFPNGIPECGTDALRFALVSYTAQSDKINLDI 772
Query: 667 KGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISEVE 726
V R+ N LWN A + P+ L+P+ +PF +WILS +N IS+
Sbjct: 773 LRVVGYRQWCNKLWNAVRFAMMKLGSGYTPPQTLSPETMPF--SCQWILSVLNKAISKAV 830
Query: 727 NGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDP----DKLAAYYTLWKVFD 782
+++F + A +Y + Y+ I+ + G++P ++ A + LW +
Sbjct: 831 VSLDAFEFSDAANTIYAWWQYQFCDVYIEAIKP--YFAGDNPTFASERAHAQHALWISLE 888
Query: 783 VLLRLLAPFTPYIAEEIYQNLIRP--FTNVESVHMLDWPKVDEKAIDEELEREMEFIRRI 840
LRLL PF P++ EE++Q L P S+ + D+P E +E++E EM+ +
Sbjct: 889 TGLRLLHPFMPFVTEELWQRLPAPKDTERKASIMICDYPSAIENWSNEKVESEMDTVLAT 948
Query: 841 VEAGSAAR 848
V+ A R
Sbjct: 949 VKCMRALR 956
>sp|Q9WY15|SYL_THEMA LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS)
>gi|7437543|pir||F72408 leucine--tRNA ligase (EC
6.1.1.4) - Thermotoga maritima (strain MSB8)
>gi|4980663|gb|AAD35261.1|AE001702_1 (AE001702)
leucyl-tRNA synthetase [Thermotoga maritima]
Length = 824
Score = 226 bits (570), Expect = 1e-57
Identities = 234/931 (25%), Positives = 390/931 (41%), Gaps = 205/931 (22%)
Query: 8 REYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKD 67
+EY P+++E+K ++ W E +++ + R + PKYY L PY SG +H+G N +I D
Sbjct: 2 KEYRPQEIEKKWQEVWEEKKVFYTPQ--RSEKPKYYALVMFPYPSGTLHVGHVKNYVIGD 59
Query: 68 MIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFAL 127
++ R++ M+GYNV GYD GLP E IE+ I E + +K
Sbjct: 60 IVARYKRMRGYNVLHPFGYDAFGLPAE-----------NAAIEKGIHPEEWTRK------ 102
Query: 128 NNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRC 187
N+ + +Q K LGI DW T EY + + + ++ GL K K ++WCP+C
Sbjct: 103 -NIATIRQQVKKLGISYDWSREIATCDEEYYKWTQWIFLQLYKNGLAYKKKAAVNWCPKC 161
Query: 188 ETALAEHEVRG-----------------------EYKLR--------------------- 203
+T LA +V+ +Y R
Sbjct: 162 KTVLANEQVKDGKCERCGTSVTIRHLEQWFFKITDYAERLLNDLDKLTGWPEHVKTMQRN 221
Query: 204 ---KDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVKVKVEFNGREEYW 260
K + FPVEG + + + ++TT P TL ++ P+ V+ V +EE
Sbjct: 222 WIGKSTGAEIDFPVEGSDTK-IRVFTTRPDTLWGVTFMALAPESPLVEELVPEEKKEE-- 278
Query: 261 ILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFKEKYEWAHRVIL 320
+ +++V + + VE E EG + Y E+ + +
Sbjct: 279 --LQEFLERVKQQDRFRRTSVE----AEKEG-----FFLGRYAINPVTGERIP----IYV 323
Query: 321 ADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLP---VYSPLDDQGKYTEGKWKGIYVKEA 377
A+++ +E GTG + P H + DF +KYG+P V P D K+
Sbjct: 324 ANYILMEYGTGAIMGVPAHDQRDFSFAKKYGIPIKVVIKPAD---------------KDL 368
Query: 378 DPKIIEHLRE-KGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKDKIIKENDE 436
DP+ +E E +G +V +G + TP S+ +K+I +E
Sbjct: 369 DPEKMEEAYEGEGIMVNSGPFD---------GTP------------SSEGIEKVINWLEE 407
Query: 437 K-VTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVELAV 495
K + K+R DW+ISRQRYWG P+PI IY E
Sbjct: 408 KGIGKRSVQYKLR---------DWLISRQRYWGAPIPI-------IY--------CEKCG 443
Query: 496 AIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFD 555
+ V E +LP + ++ + P H + V G + +R D +D + D
Sbjct: 444 VVPVPEE--DLPVRLPKDVEFLPTGQSPLSFHEGFKKT-KCPVCGGEAQRETDTMDTFVD 500
Query: 556 SGIASWASLGYPRNKELFEK--------LW-PADFIVEG-EDQVTKWFYSQQAASI---- 601
S SW L Y N L +K W P D + G E V YS+ +
Sbjct: 501 S---SWYFLRYV-NPHLEDKPFEPDDVNYWLPVDQYIGGVEHAVLHLLYSRFVTKVLHDL 556
Query: 602 --VAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPW 659
+ FD P+ + G + + G KMSKS GN++ P+E++E+ G DT R Y+L+ P
Sbjct: 557 GYLNFDE-PFTNLFTQGMIYKD-GAKMSKSKGNVVSPDEMIEKYGADTLRMYILFMAPPE 614
Query: 660 ENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVN 719
++ ++S G+E V R + LWN + ++ +N + L +K + +++
Sbjct: 615 KDAEWSDAGIEGVHRFVKRLWNTFYTVLPFVKEENTENLVLK------NSTEKELRRKLH 668
Query: 720 SLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWK 779
S+I ++ IE + + +V LS+ Y+ + + W KL L +
Sbjct: 669 SIIKKITEDIEGGFKFNTAISGLMELVNHLSQ-YLNSVPQEEWNR-----KL-----LRE 717
Query: 780 VFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREMEFIRR 839
+ + L L+PF P++AEE + +L N V WP D KA+ E+E +
Sbjct: 718 IVEKLTLALSPFAPHLAEEFWHDL----GNDSLVVQQSWPSYDPKAL------EVEEVEI 767
Query: 840 IVEAGSAARQRAKIKL---RYPVRRIIIETE 867
++ R + + + ++RI++E E
Sbjct: 768 AIQINGKVRDKVVVPVDISEEDLKRIVLERE 798
>sp|P49696|SYV_FUGRU VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|1041396|emb|CAA62967.1| (X91856) valyl-tRNA
synthetase [Fugu rubripes]
Length = 1217
Score = 222 bits (560), Expect = 2e-56
Identities = 207/896 (23%), Positives = 370/896 (41%), Gaps = 116/896 (12%)
Query: 10 YDPKKLEEKVEKFWSENEIYRKV---KELRKDGPKYYFLD--GPPYVSGAIHLGTAWNKI 64
Y P+ +E +W + ++ K + + P+ F+ PP V+G++HLG A
Sbjct: 249 YSPQYVEAAWYPWWEKQGFFKPEFGRKSIGEQNPRGIFMMCIPPPNVTGSLHLGHALTNA 308
Query: 65 IKDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKE 124
I+D + R+ M+G PG D G+ +V VE+ L ++ K +G E FI++ +
Sbjct: 309 IQDTLTRWHRMRGETTLWNPGCDHAGIATQVVVEKKL-MREKGTSRHDLGREKFIEEVWK 367
Query: 125 FALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWC 184
+ + Q K LG +DWD T+ + + R ++G++ + KR+++W
Sbjct: 368 WKNEKGDRIYHQLKKLGSSLDWDRACFTMDPKLSYAVQEAFIRMHDEGVIYRSKRLVNWS 427
Query: 185 PRCETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDY 244
+A+++ EV + + S PV G + + V
Sbjct: 428 CSLNSAISDIEVD-----KNELSGRTLLPVPGYKEK-------------VEFGV------ 463
Query: 245 DYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPR 304
V + +G +E ++A ++ +LG+ V + + + L+G +H D
Sbjct: 464 -LVSFAYKVDGSDEEVVVATTRIETMLGDTAVAVHPSDS-RYQHLKGKTVLHPFCDR--- 518
Query: 305 QKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKY 364
V+ DFV + GTG V P H D+EVG ++ L + LD+ G
Sbjct: 519 ----------KIPVVFDDFVDMSFGTGAVKITPAHDHNDYEVGVRHNLAFINILDENGFV 568
Query: 365 TEGKWKGIYVKEADPK--IIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLK 422
+ +K D + +++ L+++ + + P C R K + QW++
Sbjct: 569 INVPPPFLGMKRFDARKAVLQALKDRDQFKEIKDNPMVVPVCSRSKDIVEPLMKPQWYVS 628
Query: 423 ISKV-KDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEI 481
S + K + ++ PD + N + + DW ISRQ +WG +P
Sbjct: 629 CSDMGKQAADAVREGRLKIIPDHHSQTWFNWMDNIRDWCISRQLWWGHRIP--------- 679
Query: 482 YVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGK 541
A I V+ ++ E + +V PE+ F + +
Sbjct: 680 ------------AYFITVSDPSVKPGEDMDGHYRVSGRT--PEEAREKAAKRFNVSPDKI 725
Query: 542 DMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASI 601
+R+ +DV+D WF SGI ++ LG+P E +P + G D + W +
Sbjct: 726 ALRQDEDVLDTWFSSGINPFSILGWPNETEDLNVFYPGTLLETGHDILFFWVARMVMMGL 785
Query: 602 VAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNII--------------------------- 634
+P++ V V D G KMSKSLGN+I
Sbjct: 786 KLTGKLPFKEVYHCAVVRDAHGRKMSKSLGNVIDPLDDHIGIALEGLHAQLMDTNLDPLE 845
Query: 635 --RPEEV--------VERAGRDTFRFYMLWATNPWENLKFSWKGVEQVRRMLNILWNVYV 684
+P++V + G D RF + T+ ++ + R N LWN
Sbjct: 846 VEKPKKVQKADYPNCIPECGTDALRFALCAYTSQGRDINLDVNRILGYRHFCNKLWNAVK 905
Query: 685 LASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISEVENGIESFYLTKATRALYNF 744
A + D F P +P E D+WILSR+++ +++ + ++ T A+YNF
Sbjct: 906 FAMRTLG-DQFVPADTSPAEREESVSDRWILSRLSTAVAQCDAAFRTYDFPAITTAIYNF 964
Query: 745 VVEDLSRWYVRLIRKRLWVEGEDP--DKLAAY--YTLWKVFDVLLRLLAPFTPYIAEEIY 800
+ +L Y+ ++ ED ++ AA TL+ +V LRLLAP P++ EE+Y
Sbjct: 965 WLYELCDVYLESVKPVFIKAKEDGSCERPAAVCRQTLYTCLEVGLRLLAPLMPFVTEELY 1024
Query: 801 QNL--IRPFTNVESVHMLDWPKVDEKAID-EELEREMEFIRRIVEAGSAARQRAKI 853
Q L RP ++ S+ + +P E E+++R+++FI +V + R K+
Sbjct: 1025 QRLPRRRPQSDPPSICVTPYPDAAEFCWQCEDVDRDIDFIMGVVRTIRSLRSDYKL 1080
>sp|P47576|SYV_MYCGE VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|1361896|pir||I64236 valine--tRNA ligase (EC 6.1.1.9)
- Mycoplasma genitalium >gi|3844913|gb|AAC71557.1|
(U39714) valyl-tRNA synthetase (valS) [Mycoplasma
genitalium]
Length = 837
Score = 222 bits (559), Expect = 2e-56
Identities = 191/782 (24%), Positives = 332/782 (42%), Gaps = 143/782 (18%)
Query: 48 PPYVSGAIHLGTAWNKIIKDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKK 107
PP ++G +H+G A+ I D I+RF+ MQG+++ PG+D G+ + K E+ + +K
Sbjct: 45 PPNLTGTLHIGHAFEVSITDQIMRFKKMQGFSINWIPGFDHAGIATQTKYEKIALKENQK 104
Query: 108 EIEEKIGVENFIKKCKEFALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKR 167
+ ++ + +ALN +I+ Q K LG+ ++W T+ + + K
Sbjct: 105 YFDADDDKKS--EMIMNWALNQSEIIKNQLKSLGVCLNWSETKFTLSEQANKIVNNCFKN 162
Query: 168 AWEKGLLEKDKRVLHWCPRCETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTT 227
+E G + + +++W + TA++ EV K YV + + + L++ TT
Sbjct: 163 LYENGFIYQAYTLVNWDTKLNTAISNIEVIN--KPVNQHLHYVVYKLANDSKQELIVATT 220
Query: 228 TPWTLPANLAVSAHP-DYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKG 286
P T+ A++ + +P D Y +W +K+ VV G
Sbjct: 221 RPETIFADVCLLVNPKDKRYTN----------FW-------NKL---------VVNPLTG 254
Query: 287 RELEGLRYVHILMDEYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEV 346
+++ V+ +V ++ GTG++ P H D+E+
Sbjct: 255 KQIP---------------------------VVTDSYVDIKFGTGILKCTPAHDFNDYEI 287
Query: 347 GQKYGLPVYSPLDDQGKYTEG--KWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHC 404
KY S +D G + K++G+ V +A KI++ L + LVK+ +
Sbjct: 288 NTKYKFDFLSCIDSNGILNQNASKFQGLSVLQARNKIVKWLEKNKLLVKSIPLTSNVGFS 347
Query: 405 WRCKTPLIFRATDQWFLKISKVKDKIIKENDEKVTWYPDWVKIRFD----NGVRDSGDWV 460
R T + + QWF+ + K+KD + + YPD++ RF+ N + W
Sbjct: 348 ERSGTVVEPMLSKQWFVDLPKLKDHLYLKK------YPDFIPKRFNKQVSNWLNKLKPWC 401
Query: 461 ISRQRYWGIPLPIW-QSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEE 519
ISRQ WG +P+W ++ GEI VVG E P
Sbjct: 402 ISRQLIWGHKIPVWFENNTGEI-VVG-------------------EKPSK---------- 431
Query: 520 KLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPA 579
N ++ R KDV+D WF S + L + ++ E
Sbjct: 432 -------------------NLQNYTRSKDVLDTWFSSSLWPLICLNWEQDDSFHE----T 468
Query: 580 DFIVEGEDQVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEV 639
+ +V G D + W S +P++ V +HG V DE+ KMSKSL N I P ++
Sbjct: 469 ELLVTGYDILFFWVLRMLFNSFFETKKLPFKTVLIHGLVRDEQNRKMSKSLNNGIDPVDL 528
Query: 640 VERAGRDTFRFYMLWATNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRK 699
+ G D R ++ P ++L FS + ++ LN LWNV + L+N
Sbjct: 529 IRNYGADAVRLFLCSNHTPGDDLIFSEQKIKSAWNFLNKLWNV---TKFVIQLENDQEIS 585
Query: 700 LNPDELPFREEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRK 759
+ D+L E WIL++++ +I ++ ++ F L A + L FV +D ++ I+K
Sbjct: 586 YDLDKLSLSE--TWILAKLDKVIQKITKLLDKFQLALANQILVKFVWDDFCNTFIEAIKK 643
Query: 760 RLWVEGEDPDKL--AAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLD 817
+P++L +YT V + LL+ P+++E IYQ N +SV
Sbjct: 644 -------EPNQLKPQLFYTAKSVLSNIAILLSITVPFLSERIYQQF-----NNKSVMQAT 691
Query: 818 WP 819
WP
Sbjct: 692 WP 693
>gb|AAF63175.1|AC010657_11 (AC010657) T5E21.11 [Arabidopsis thaliana]
Length = 1115
Score = 221 bits (558), Expect = 3e-56
Identities = 215/918 (23%), Positives = 379/918 (40%), Gaps = 168/918 (18%)
Query: 8 REYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIK- 66
++Y P +E+ +W ++++++ + + P + + PP V+GA+H+G A I+
Sbjct: 138 KQYSPATVEKSWYAWWEKSDLFKA--DAKSSKPPFVIVLPPPNVTGALHIGHALTSAIEV 195
Query: 67 ------DMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIK 120
D IIR++ M GYN PG D G+ +V VE+ + ++ + +G E F+K
Sbjct: 196 SLAYCLDTIIRWKRMSGYNALWVPGVDHAGIATQVVVEKKI-MRDRGMTRHDVGREEFVK 254
Query: 121 KCKEFALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRV 180
+ ++ + Q + LG +DW T+ + ++ R +++GL+ +D R+
Sbjct: 255 EVWKWKNQYGGTILTQLRRLGASLDWSRECFTMDEQRSKAVTEAFVRLYKEGLIYRDIRL 314
Query: 181 LHWCPRCETALAEHEVR----GEYKLRKDPSIYVK-----------FPVEGKENEYLLIW 225
++W TA+++ EV E L K P Y K +P+EG E +++
Sbjct: 315 VNWDCILRTAISDVEVEYIDIKEKTLLKVPG-YEKPVEFGLLTSFAYPLEGGLGE-VIVA 372
Query: 226 TTTPWTLPANLAVSAHPD---YDYVKVKV---EFNGREEYWILAKALVDKVLGEIGVKGE 279
TT T+ + A++ HPD Y ++ K FNGR+ I LVD G VK
Sbjct: 373 TTRVETMLGDTAIAIHPDDARYKHLHGKFAVHPFNGRKLPIICDGILVDPNFGTGCVK-- 430
Query: 280 VVEEFKGRELEGLRYVHILMDEYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGH 339
I P E ++++ +F+ + G ++T +
Sbjct: 431 -----------------ITPAHDPNDCEVGKRHK-------LEFINIFTDDGKINT---N 463
Query: 340 GEEDFEVGQKYGLPVYSPLDDQGKYTEGKWKGIYVKEADPKIIEHLREKGYLVKAGEIEH 399
G DF G+P ++ A ++E L+++G A E
Sbjct: 464 GGSDFA-----GMPRFA--------------------AREAVVEALQKQGLYRGAKNNEM 498
Query: 400 KYPHCWRCKTPLIFRATDQWFLKISKV----KDKIIKENDEKVTWYPDWVKIRFDNGVRD 455
+ C R + QW++ S + D I + ++K+ + P + + +
Sbjct: 499 RLGLCSRTNDVIEPMIKPQWYVNCSMIGKEALDVAITDENKKLEFVPKQYTAEWRRWLEN 558
Query: 456 SGDWVISRQRYWGIPLPIWQS--EDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEK 513
DW ISRQ +WG +P W + E+ ++ VG++ + +A R E E
Sbjct: 559 IRDWCISRQLWWGHRIPAWYATLEEDQLKEVGAYSDHWVVA--------RTEDDAREEAA 610
Query: 514 LKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELF 573
K + +K ++ R DV+D WF SG+ + LG+P + F
Sbjct: 611 QKFLGKKF--------------------ELTRDPDVLDTWFSSGLFPLSVLGWPDVTDDF 650
Query: 574 EKLWPADFIVEGEDQVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNI 633
+ +P + G D + W + VP+ +V H + D G KMSKSLGN+
Sbjct: 651 KAFYPTSVLETGHDILFFWVARMVMMGMKLGGEVPFSKVYFHPMIRDAHGRKMSKSLGNV 710
Query: 634 IRPEEVVE-------------------------------------RAGRDTFRFYMLWAT 656
I P EV+ G D RF ++ T
Sbjct: 711 IDPLEVINGVTLEGLHKRLEEGNLDPKEVIVAKEGQVKDFPNGIPECGTDALRFALVSYT 770
Query: 657 NPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILS 716
+ + V R+ N LWN A + P+ L+P+ +PF +WILS
Sbjct: 771 AQSDKINLDILRVVGYRQWCNKLWNAVRFAMMKLGDGYTPPQTLSPETMPF--SCQWILS 828
Query: 717 RVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDP----DKLA 772
+N IS+ +++F + A +Y + Y+ I+ + G++P ++
Sbjct: 829 VLNKAISKTVVSLDAFEFSDAANTIYAWWQYQFCDVYIEAIKP--YFAGDNPTFASERAH 886
Query: 773 AYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRP--FTNVESVHMLDWPKVDEKAIDEEL 830
A + LW + LRLL PF P++ EE++Q L P S+ + D+P E +E++
Sbjct: 887 AQHALWISLETGLRLLHPFMPFVTEELWQRLPAPKDTERKASIMICDYPSAIENWSNEKV 946
Query: 831 EREMEFIRRIVEAGSAAR 848
E EM+ + V+ A R
Sbjct: 947 ESEMDTVLATVKCMRALR 964
>emb|CAB60428.1| (AL110500) contains similarity to Pfam domain: PF00133 (tRNA
synthetases class I (I, L, M and V)), Score=910.6,
E-value=1.5e-270, N=1~cDNA EST yk4g12.5 comes from this
gene~cDNA EST yk4g12.3 comes from this gene~cDNA EST
yk49e5.3 comes from this gene~c>
Length = 1050
Score = 219 bits (552), Expect = 1e-55
Identities = 214/907 (23%), Positives = 376/907 (40%), Gaps = 129/907 (14%)
Query: 23 WSENEIYRKVKELRKDGPKYYFLDG------PPYVSGAIHLGTAWNKIIKDMIIRFRTMQ 76
W E E + K + + K P D PP V+G +H+G A ++D I RF M
Sbjct: 95 WWEKEGFFKPEYIDKLNPGSNPADSFTVCIPPPNVTGNLHVGHALATTVEDTITRFNRMH 154
Query: 77 GYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIMTEQ 136
G PG D G+ +V VE+ L + + +G + F ++ + ++ +Q
Sbjct: 155 GKRTLFNPGCDHAGIATQVVVEKRLK-RERGLTRHDLGRDRFNQEVWHWKNEKGDVIYDQ 213
Query: 137 FKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHEV 196
F+ LG +DWD T+ + + R E G + + R+++W +A+++ EV
Sbjct: 214 FRKLGASVDWDRAVFTMDPKMCRAVTEAFIRMHESGTIYRSNRLVNWSCALRSAISDIEV 273
Query: 197 RGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVKVKVEFNGR 256
K S + P K+ E+ ++ + Y + G
Sbjct: 274 D---KKELTGSTLIAVPGYDKKIEFGVL-----------------NSFAY-----KIQGS 308
Query: 257 EEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFKEKYEWAH 316
+E +++ ++ +LG+ GV ++ + + L G + +H + +
Sbjct: 309 DEEIVVSTTRIETMLGDSGVAVHPDDQ-RYKHLVGKQCIHPFIPT-------------RN 354
Query: 317 RVILAD-FVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTEG--KWKGIY 373
I AD FV +E GTG V P H D+EVG + LP ++ + D G ++G ++ G+
Sbjct: 355 LPIFADSFVEMEFGTGAVKITPAHDHNDYEVGIRQNLPFHNCITDDGLISQGCGEFSGMK 414
Query: 374 VKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKDKIIKE 433
+A +IE L+EKG + P C R K + QW++K + + +K +
Sbjct: 415 RFDARTAVIEALKEKGLYRGKEDNPMVVPTCSRSKDVIEPILKPQWYVKCAHMAEKAVAA 474
Query: 434 -NDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVE 492
+ + P++ K ++ + S DW ISRQ +WG +P + +
Sbjct: 475 VANGDLQIIPEFHKATWNRWLESSRDWCISRQLWWGHRIPAYYISFAD------------ 522
Query: 493 LAVAIEVNGERIELPE-SYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVD 551
G LPE +Y + +E L +A I+ ++ +DV+D
Sbjct: 523 --------GREQPLPEENYWVSARTEQEALAKAAQKFQVPEAEIL------LKWDEDVLD 568
Query: 552 VWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVAFDTVPYRR 611
WF SG+ +A G+P + + +P + G D + W + +P++
Sbjct: 569 TWFSSGMWPFAVFGWPDATKDMDLFFPGAVLETGHDILFFWVARMVFMAQELTGKLPFKE 628
Query: 612 VAMHGYVLDEKGDKMSKSLGNIIRPEEVVE------------------------------ 641
+ +H + D G KMSKSLGN+I P +V+
Sbjct: 629 ILLHAMIRDAHGRKMSKSLGNVIDPLDVIRGISLNDLQAQLLGGNLDEKEIAVAKEGQAR 688
Query: 642 -------RAGRDTFRFYMLWATNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDN 694
G D RF +L T+ ++ V R+ N LW V A +S
Sbjct: 689 DYPDGIPECGVDALRFALLSYTSQGRDINLDVLRVHGYRKFCNKLWQVVRFALARIS--- 745
Query: 695 FDPRKLNPDELPFRE---EDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSR 751
P + E+ + D WILSR+ + E ++++ T+AT YNF + D
Sbjct: 746 DKPEQKPTFEINLKSATPTDLWILSRLAKAVKETNEALKAYNFTQATTVTYNFWLYDFCD 805
Query: 752 WYVRLIRKRLWVEGEDPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIR----PF 807
YV I+ L+ + + A L K D LRL++P P+I+EE++Q + R +
Sbjct: 806 VYVETIKPVLYGDNTTL-RQVAISVLHKCIDTGLRLISPLMPFISEELWQRMPRLDDSDY 864
Query: 808 TNVESVHMLDWPKVD--EKAIDEELEREMEFIRRIVEAGSAARQRAKIKLRYPVRRIIIE 865
T+ S+ + +P EK +E+LE EF + ++ + R +K +I+ E
Sbjct: 865 TS-PSIIVAQYPLTQKYEKYQNEKLEAAFEFAQELIGKVRSLRADYDLKKTKITMQILSE 923
Query: 866 T-EDETV 871
T EDE++
Sbjct: 924 TPEDESM 930
>gb|AAF58412.1| (AE003819) CG4062 gene product [Drosophila melanogaster]
Length = 1049
Score = 217 bits (548), Expect = 4e-55
Identities = 224/920 (24%), Positives = 360/920 (38%), Gaps = 184/920 (20%)
Query: 10 YDPKKLEEKVEKFWSENEIY-----RKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKI 64
Y P+ +E + +W + + R + K+ + PP V+G++HLG A
Sbjct: 94 YSPRYVEAQWYSWWEKEGFFTPEYGRASIDAPNPNGKFVMIIPPPNVTGSLHLGHALTNA 153
Query: 65 IKDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKE 124
I+D I R+ M+G PG D G+ +V VE+ L + +K +G E FI++ +
Sbjct: 154 IEDAITRYHRMKGRTTLWVPGCDHAGIATQVVVEKLL-WRDEKLSRHDLGREKFIERIWD 212
Query: 125 FALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWC 184
+ + EQ K LG DW T+ + + R E+G + + R+++W
Sbjct: 213 WRREKGGRIYEQLKSLGSSYDWTRVAFTMDPKLCRAVTEAFVRLHEEGSIYRSSRLVNWS 272
Query: 185 PRCETALAEHEVR------------GEYKLRKDPSIYVKF--PVEGKENEYLLIWTTTPW 230
+A+++ EV Y+ + + + +KF VEG + E +++ TT
Sbjct: 273 CTLRSAISDIEVDKVEIPGRTFLSIPGYEDKVEFGVLIKFAYKVEGSDEE-IIVATTRIE 331
Query: 231 TLPANLAVSAHPDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELE 290
T+ + AV+ HP D K +G+ VV F R L
Sbjct: 332 TMLGDTAVAVHPQDDRYK---HLHGK----------------------FVVHPFSTRRLP 366
Query: 291 GLRYVHILMDEYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKY 350
++ +FV + GTG V P H D+EVG++
Sbjct: 367 ---------------------------IVCDEFVDMAFGTGAVKITPAHDPNDYEVGKRC 399
Query: 351 GLPVYSPLDDQGKY--TEGKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCK 408
LP + +D G G++ G+ E KI+E L+ + P C R K
Sbjct: 400 NLPFITIFNDDGYIIGDYGEFTGMKRFECRKKILEKLKALNLYRETLNNPMVVPICSRSK 459
Query: 409 TPLIFRATDQWFLKISKV-----------KDKIIKENDEKVTWYPDWVKIRFDNGVRDSG 457
+ QW++ S + + KII E+ K TWY W+ +G+R
Sbjct: 460 DVVEPLIKPQWYVSCSDMAASATEAVRSGELKIIPEHHTK-TWY-HWM-----DGIR--- 509
Query: 458 DWVISRQRYWGIPLPIWQ-----------SEDGEIYVVGSWRELVELAVAIEVNGERIEL 506
DW +SRQ +WG +P + S D E Y + +
Sbjct: 510 DWCVSRQLWWGHRIPAYHVSFTDPSLQTGSNDDEQYWI---------------------V 548
Query: 507 PESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGY 566
S E L E+ G VDA I +++ +DV+D WF SGI ++ G+
Sbjct: 549 ARSEAEALTKAAERFG--------VDASKIV-----LKQDEDVLDTWFSSGIFPFSVFGW 595
Query: 567 PRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKM 626
P + + +P + G D + W +P++ V +H V D G KM
Sbjct: 596 PDQTKDLQTFYPTSLLETGHDILFFWVARMVFFGQKLLGKLPFKEVYLHPMVRDAHGRKM 655
Query: 627 SKSLGNIIRPEEVVE-------------------------------------RAGRDTFR 649
SKSLGN+I P +V+ G D R
Sbjct: 656 SKSLGNVIDPMDVIRGITLEGLHAQLVGSNLDPREIEKAKAGQKQDYPQGIPECGSDALR 715
Query: 650 FYMLWATNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMS-LDNFDPRKLNPDELPFR 708
F + ++ V R N LWN A Y + + FD
Sbjct: 716 FALCAYITQARDINLDINRVLGYRFFCNKLWNATKFALLYFTGSEKFDTEL--SASAAIN 773
Query: 709 EEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDP 768
+ D WILSR+ + I G ES+ AT A Y F + DL Y+ + K ++ G +
Sbjct: 774 QMDAWILSRLAAAIEACNTGFESYDFAAATSACYAFWLYDLCDVYLECL-KPIFQSGSEE 832
Query: 769 DKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDE 828
+ AA TL+ D LRLL+PF P+I EE+YQ L R S+ + +P +
Sbjct: 833 QQTAARRTLYVCLDYGLRLLSPFMPFITEELYQRLPRA-NPAPSICVASYPS-NTSWRST 890
Query: 829 ELEREMEFIRRIVEAGSAAR 848
++E ++EF+++ +AR
Sbjct: 891 KIESDVEFVQKAARIIRSAR 910
>sp|P75304|SYV_MYCPN VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|2146697|pir||S73687 valine--tRNA ligase (EC 6.1.1.9)
valS - Mycoplasma pneumoniae (strain ATCC 29342)
>gi|1674039|gb|AAB96009.1| (AE000034) valyl-tRNA
synthetase [Mycoplasma pneumoniae]
Length = 838
Score = 212 bits (534), Expect = 2e-53
Identities = 197/847 (23%), Positives = 342/847 (40%), Gaps = 147/847 (17%)
Query: 9 EYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDM 68
+YD K + + WS ++ +K+ + + PP ++G +H+G A+ I D
Sbjct: 10 QYDFKTVSTGLYDSWSSASFFKP----QKNKVPFTAILPPPNLTGTLHIGHAFEVSITDQ 65
Query: 69 IIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALN 128
I+RF+ ++GY V PG+D G+ + K E+ L +T E + + +K ++AL
Sbjct: 66 IMRFKRLRGYGVNWIPGFDHAGIATQTKYEK-LARETNPEYFQAPRKQK-VKMIMDWALT 123
Query: 129 NLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCE 188
+ Q K LG ++W+ T+ + + + + +E+G + + + +++W +
Sbjct: 124 QGDTIQSQIKSLGASLNWNQVNFTLSKKASQIVNDSFIQLFEQGFIYQAETLVNWDTKLN 183
Query: 189 TALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVK 248
TA++ EV K Y+ + + + L++ TT P T+ ++ + HP
Sbjct: 184 TAISNIEVIN--KPVDQQLYYIAYKLANNPKKRLVVATTRPETIFVDVCLFVHPK----- 236
Query: 249 VKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEF 308
DK VK +VV G +
Sbjct: 237 -------------------DKHYHSF-VKQKVVNPLTGALMP------------------ 258
Query: 309 KEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTEG- 367
V +V + GTG++ P H DF + +KY LP S +D G E
Sbjct: 259 ---------VFTDSYVDKKFGTGVLKCTPAHDFNDFALNEKYRLPFVSCIDHNGLLNEHA 309
Query: 368 -KWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKV 426
++ G+ V A +++E L+ + LVK + R T + + QWF+ + K+
Sbjct: 310 KQFTGLTVSAARQQVVEFLQTQKLLVKTMPLTSNVGFSERSDTVVEPLLSKQWFVDLPKL 369
Query: 427 KDKIIKENDEKVTWYPDWVKIRFDNGVR----DSGDWVISRQRYWGIPLPIWQSEDGEIY 482
K + + YP+ + RF+ V W ISRQ WG P+P+W +
Sbjct: 370 KKALA------IKKYPELIPKRFNKQVTRWLSQLKPWCISRQLIWGHPIPVWTHKQSGAL 423
Query: 483 VVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKD 542
VGS P D ++
Sbjct: 424 HVGS----------------------------------TAPTDK--------------QN 435
Query: 543 MRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIV 602
+ DV+D WF S + L + +NK P D +V G D + W S
Sbjct: 436 YTQSTDVLDTWFSSSLWPLICLDWHKNKHFV----PTDLLVTGYDILFFWVLRMTFNSYF 491
Query: 603 AFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENL 662
+P+++V +HG V D + KMSKSL N I P +++ G D R ++ P ++L
Sbjct: 492 QTKQLPFKQVLIHGLVRDAQNRKMSKSLNNGINPMDLIRDYGADATRLFLTSNHTPGDDL 551
Query: 663 KFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLI 722
F+ + ++ LN LWNV + Y+ + + LP ++WI +++ LI
Sbjct: 552 IFNEQKLKSAANFLNKLWNV----TKYVLQLGEQAKTVPSTHLPSTLSERWIWAKLKQLI 607
Query: 723 SEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWK-VF 781
+ ++ + L A +AL NF+ D ++ I++ ED L YT K V
Sbjct: 608 VQTTKLLDKYQLALANQALVNFIWNDFCNTFIETIKQ------EDTALLPQLYTTAKTVL 661
Query: 782 DVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREMEFIRRIV 841
+ +L+ TP++AE IYQ + SV WP KA+ + + +V
Sbjct: 662 STAVVMLSTVTPFLAERIYQQF-----HSGSVMQASWPTA--KAV-----KPPKLFADVV 709
Query: 842 EAGSAAR 848
EA S+ R
Sbjct: 710 EAVSSLR 716
>pir||T39630 valine-tRNA ligase precursor, mitochondrial - fission yeast
(Schizosaccharomyces pombe) >gi|7493608|pir||T39665
valine-tRNA ligase precursor, mitochondrial - fission
yeast (Schizosaccharomyces pombe)
>gi|3738140|emb|CAA21241.1| (AL031852) valyl-trna
synthetase, mitochondrial [Schizosaccharomyces pombe]
>gi|3738176|emb|CAA21312.1| (AL031856) valyl-trna
synthetase, mitochondrial precursor [Schizosaccharomyces
pombe]
Length = 980
Score = 210 bits (530), Expect = 5e-53
Identities = 203/865 (23%), Positives = 337/865 (38%), Gaps = 147/865 (16%)
Query: 2 IKEPEFREYDPKKLEEKVEKFWSENEIYRKVKELRKDG-PK----YYFLDGPPYVSGAIH 56
+ P + Y+PK +E +W ++ + E DG PK + PP V+GA+H
Sbjct: 89 LDSPALKSYNPKAVESAWYDWWVKSGFFEP--EFGPDGKPKKEGVFVITSPPPNVTGALH 146
Query: 57 LGTAWNKIIKDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVE 116
+G A I+D + R+ M G V G+D GL + VE+ L T+K+ +
Sbjct: 147 IGHALTIAIQDSLARWNRMLGKTVLFLGGFDHAGLSTQSVVEKKLWY-TQKKTRHDYPRD 205
Query: 117 NFIKKCKEFALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEK 176
F+ E+ + Q LG DW T+ + T R E+ ++ +
Sbjct: 206 KFVDIVWEWKEEYHNRIKNQMSRLGGSFDWTREAFTMDENLSRAVVETFVRLHEENIIYR 265
Query: 177 DKRVLHWCPRCETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANL 236
R+++WC +T L+ EV V G+ + + P +
Sbjct: 266 ANRLVNWCTALQTTLSNLEVEN-------------VDVPGRT-----LLKVPGYDEPVEV 307
Query: 237 AVSAHPDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVH 296
V + G +E ++A + +LG+ V + RY H
Sbjct: 308 GV-------LTSIAYAVEGSDERIVIATTRPETLLGDTAVAVHPQDP---------RYKH 351
Query: 297 ILMDEYPRQKEFKEKYEWAHRVILAD--FVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPV 354
+ K K + I+ D V +E GTG V P H D+EVG+++ L
Sbjct: 352 L------HGKFVKHPFCNRSIPIICDDIIVDMEFGTGAVKITPAHDPNDYEVGKRHNLEF 405
Query: 355 YSPLDDQGKYTE--GKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLI 412
+ D G E G++ G+ A K++E L+E G V E P C + +
Sbjct: 406 INIFTDDGLLNENCGEFAGMKRFTARVKVVERLKELGLFVGTKENPMVIPLCGKTSDIIE 465
Query: 413 FRATDQWFL---KISKVKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGI 469
QW++ +++ +++K + ++ PD + F + + DW ISRQ +WG
Sbjct: 466 PVMKPQWWVNQKEMAAAAAEVVKSGEIEIA--PDMSRREFIRWMENIQDWCISRQLWWGH 523
Query: 470 PLPIW----------QSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEE 519
+P + +G +V G E E G+ L +
Sbjct: 524 RIPAYFVNLADEPSQDRSEGRYWVTGRTLEQAEEKAKAAFPGKSFTLEQD---------- 573
Query: 520 KLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPA 579
+DV+D WF SG+ +++LG+P++ +E +P
Sbjct: 574 ---------------------------EDVLDTWFSSGLWPFSTLGWPKDTSDYENFYPT 606
Query: 580 DFIVEGEDQVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEV 639
+ G D + W + +P++RV H V D +G KMSKSLGN++ P +V
Sbjct: 607 TLMETGWDILFFWIARMVMLGLKLTGKIPFKRVFCHALVRDAQGRKMSKSLGNVVDPIDV 666
Query: 640 VE-------------------------------------RAGRDTFRFYMLWATNPWENL 662
+E + G D RF + T +L
Sbjct: 667 IEGISLQALHDKLLVGNLDSREVEKAKKGQRLSYPKGIPQCGTDALRFTLCSLTTGGRDL 726
Query: 663 KFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREE--DKWILSRVNS 720
VE R+ N L+N A + NF P K +L E +KWI R+N
Sbjct: 727 NLDILRVEGYRKFCNKLYNATKFALGRLG-SNFVPNK--TADLTGNESLVEKWIFHRLNI 783
Query: 721 LISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKV 780
+ + +E +AT A++ F + +L Y+ K L +G + + +A TL+ V
Sbjct: 784 AAAAMNKNMEEMNFLQATSAVHQFWLYELCDVYIE-NSKYLLSDGTEVQQESAKQTLYTV 842
Query: 781 FDVLLRLLAPFTPYIAEEIYQNLIR 805
D LRL+ PF PY+ EE++Q L R
Sbjct: 843 LDNALRLMHPFMPYVTEEMWQRLPR 867
>gi|6321531 mitochondrial and cytoplasmic valyl-tRNA synthetase; Vas1p
[Saccharomyces cerevisiae]
>gi|1711655|sp|P07806|SYV_YEAST VALYL-TRNA SYNTHETASE,
MITOCHONDRIAL PRECURSOR (VALINE--TRNA LIGASE) (VALRS)
>gi|2144552|pir||SYBYVT valine--tRNA ligase (EC 6.1.1.9)
- yeast (Saccharomyces cerevisiae)
>gi|1323141|emb|CAA97097.1| (Z72879) ORF YGR094w
[Saccharomyces cerevisiae]
Length = 1104
Score = 207 bits (522), Expect = 5e-52
Identities = 204/862 (23%), Positives = 342/862 (39%), Gaps = 146/862 (16%)
Query: 2 IKEPEFREYDPKKLEEKVEKFWSENEIYRKVKELRKDG---PKYYFL--DGPPYVSGAIH 56
+ +P + Y+P +E +W + ++ E DG P+ F PP V+GA+H
Sbjct: 140 LDDPALKAYNPANVESSWYDWWIKTGVFEP--EFTADGKVKPEGVFCIPAPPPNVTGALH 197
Query: 57 LGTAWNKIIKDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVE 116
+G A I+D +IR+ M+G V PG+D G+ + VE+ + K +K + G E
Sbjct: 198 IGHALTIAIQDSLIRYNRMKGKTVLFLPGFDHAGIATQSVVEKQIWAKDRKTRHD-YGRE 256
Query: 117 NFIKKCKEFALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEK 176
F+ K E+ + Q + LG DW T+ E +S R ++G++ +
Sbjct: 257 AFVGKVWEWKEEYHSRIKNQIQKLGASYDWSREAFTLSPELTKSVEEAFVRLHDEGVIYR 316
Query: 177 DKRVLHWCPRCETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANL 236
R+++W + TA++ EV KD V G + E + T + P
Sbjct: 317 ASRLVNWSVKLNTAISNLEVEN-----KDVKSRTLLSVPGYD-EKVEFGVLTSFAYPVI- 369
Query: 237 AVSAHPDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVH 296
G +E I+A + + G+ V ++ + + L G H
Sbjct: 370 ------------------GSDEKLIIATTRPETIFGDTAVAVHPDDD-RYKHLHGKFIQH 410
Query: 297 ILMDEYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYS 356
+ PR+ + + V +E GTG V P H + D+ G+++ L +
Sbjct: 411 PFL---PRKIPI---------ITDKEAVDMEFGTGAVKITPAHDQNDYNTGKRHNLEFIN 458
Query: 357 PLDDQGKYTEG---KWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIF 413
L D G E +W+G+ +A K+IE L+EK V + E P C R +
Sbjct: 459 ILTDDGLLNEECGPEWQGMKRFDARKKVIEQLKEKNLYVGQEDNEMTIPTCSRSGDIIEP 518
Query: 414 RATDQWFLKISKV-KDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLP 472
QW++ S++ KD I D ++T P + + + + + DW ISRQ +WG P
Sbjct: 519 LLKPQWWVSQSEMAKDAIKVVRDGQITITPKSSEAEYFHWLGNIQDWCISRQLWWGHRCP 578
Query: 473 IW---------QSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGP 523
++ DG+ +V G E E A + + L +
Sbjct: 579 VYFINIEGEEHDRIDGDYWVAGRSMEEAEKKAAAKYPNSKFTLEQD-------------- 624
Query: 524 EDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIV 583
+DV+D WF SG+ +++LG+P + E +P +
Sbjct: 625 -----------------------EDVLDTWFSSGLWPFSTLGWPEKTKDMETFYPFSMLE 661
Query: 584 EGEDQVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEV---- 639
G D + W + +VP++ V H V D +G KMSKSLGN+I P +V
Sbjct: 662 TGWDILFFWVTRMILLGLKLTGSVPFKEVFCHSLVRDAQGRKMSKSLGNVIDPLDVITGI 721
Query: 640 ------------------VERA---------------GRDTFRFYMLWATNPWENLKFSW 666
VE+A G D RF + T ++
Sbjct: 722 KLDDLHAKLLQGNLDPREVEKAKIGQKESYPNGIPQCGTDAMRFALCAYTTGGRDINLDI 781
Query: 667 KGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISEVE 726
VE R+ N ++ A + D++ P +KWIL ++ V
Sbjct: 782 LRVEGYRKFCNKIYQATKFALMRLG-DDYQPPATEGLSGNESLVEKWILHKLTETSKIVN 840
Query: 727 NGIESFYLTKATRALYNFVVEDLSRWYVRLI-----RKRLWVEGEDPDKLAAYYTLWKVF 781
++ +T ++Y F WY+ K L EG +K +A TL+ +
Sbjct: 841 EALDKRDFLTSTSSIYEF-------WYLICDVYIENSKYLIQEGSAIEKKSAKDTLYILL 893
Query: 782 DVLLRLLAPFTPYIAEEIYQNL 803
D L+L+ PF P+I+EE++Q L
Sbjct: 894 DNALKLIHPFMPFISEEMWQRL 915
>gb|AAA35207.1| (J02719) valyl-tRNA synthetase [Saccharomyces cerevisiae]
Length = 1104
Score = 207 bits (521), Expect = 6e-52
Identities = 204/862 (23%), Positives = 342/862 (39%), Gaps = 146/862 (16%)
Query: 2 IKEPEFREYDPKKLEEKVEKFWSENEIYRKVKELRKDG---PKYYFL--DGPPYVSGAIH 56
+ +P + Y+P +E +W + ++ E DG P+ F PP V+GA+H
Sbjct: 140 LDDPALKGYNPANVESSWYDWWIKTGVFEP--EFTADGKVKPEGVFCIPAPPPNVTGALH 197
Query: 57 LGTAWNKIIKDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVE 116
+G A I+D +IR+ M+G V PG+D G+ + VE+ + K +K + G E
Sbjct: 198 IGHALTIAIQDSLIRYNRMKGKTVLFLPGFDHAGIATQSVVEKQIWAKDRKTRHD-YGRE 256
Query: 117 NFIKKCKEFALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEK 176
F+ K E+ + Q + LG DW T+ E +S R ++G++ +
Sbjct: 257 AFVGKVWEWKEEYHSRIKNQIQKLGASYDWSREAFTLSPELTKSVEEAFVRLHDEGVIYR 316
Query: 177 DKRVLHWCPRCETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANL 236
R+++W + TA++ EV KD V G + E + T + P
Sbjct: 317 ASRLVNWSVKLNTAISNLEVEN-----KDVKSRTLLSVPGYD-EKVEFGVLTSFAYPVI- 369
Query: 237 AVSAHPDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVH 296
G +E I+A + + G+ V ++ + + L G H
Sbjct: 370 ------------------GSDEKLIIATTRPETIFGDTAVAVHPDDD-RYKHLHGKFIQH 410
Query: 297 ILMDEYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYS 356
+ PR+ + + V +E GTG V P H + D+ G+++ L +
Sbjct: 411 PFL---PRKIPI---------ITDKEAVDMEFGTGAVKITPAHDQNDYNTGKRHNLEFIN 458
Query: 357 PLDDQGKYTEG---KWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIF 413
L D G E +W+G+ +A K+IE L+EK V + E P C R +
Sbjct: 459 ILTDDGLLNEECGPEWQGMKRFDARKKVIEQLKEKNLYVGQEDNEMTIPTCSRSGDIIEP 518
Query: 414 RATDQWFLKISKV-KDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLP 472
QW++ S++ KD I D ++T P + + + + + DW ISRQ +WG P
Sbjct: 519 LLKPQWWVSQSEMAKDAIKVVKDGQITITPKSSEAEYFHWLGNIQDWCISRQLWWGHRCP 578
Query: 473 IW---------QSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGP 523
++ DG+ +V G E E A + + L +
Sbjct: 579 VYFINIEGEEHDRIDGDYWVAGRSMEEAEKKAAAKYPNSKFTLEQD-------------- 624
Query: 524 EDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIV 583
+DV+D WF SG+ +++LG+P + E +P +
Sbjct: 625 -----------------------EDVLDTWFSSGLWPFSTLGWPEKTKDMETFYPFSMLE 661
Query: 584 EGEDQVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEV---- 639
G D + W + +VP++ V H V D +G KMSKSLGN+I P +V
Sbjct: 662 TGWDILFFWVTRMILLGLKLTGSVPFKEVFCHSLVRDAQGRKMSKSLGNVIDPLDVITGI 721
Query: 640 ------------------VERA---------------GRDTFRFYMLWATNPWENLKFSW 666
VE+A G D RF + T ++
Sbjct: 722 KLDDLHAKLLQGNLDPREVEKAKIGQKESYPNGIPQCGTDAMRFALCAYTTGGRDINLDI 781
Query: 667 KGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISEVE 726
VE R+ N ++ A + D++ P +KWIL ++ V
Sbjct: 782 LRVEGYRKFCNKIYQATKFALMRLG-DDYQPPATEGLSGNESLVEKWILHKLTETSKIVN 840
Query: 727 NGIESFYLTKATRALYNFVVEDLSRWYVRLI-----RKRLWVEGEDPDKLAAYYTLWKVF 781
++ +T ++Y F WY+ K L EG +K +A TL+ +
Sbjct: 841 EALDKRDFLTSTSSIYEF-------WYLICDVYIENSKYLIQEGSAIEKKSAKDTLYILL 893
Query: 782 DVLLRLLAPFTPYIAEEIYQNL 803
D L+L+ PF P+I+EE++Q L
Sbjct: 894 DNALKLIHPFMPFISEEMWQRL 915
>sp|O58698|SYL_PYRHO LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS)
>gi|7437640|pir||H71087 leucine--tRNA ligase (EC
6.1.1.4) - Pyrococcus horikoshii
>gi|3257379|dbj|BAA30062.1| (AP000004) 967aa long
hypothetical leucyl-tRNA synthetase [Pyrococcus
horikoshii]
Length = 967
Score = 205 bits (516), Expect = 2e-51
Identities = 253/991 (25%), Positives = 416/991 (41%), Gaps = 153/991 (15%)
Query: 9 EYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDM 68
E + K +EEK +K W E +I+ + K+Y PY+SG +H+G A I D+
Sbjct: 3 ELNFKAIEEKWQKRWLEAKIFEPNIRDKPKEKKFYITVAFPYLSGHLHVGHARTYTIPDV 62
Query: 69 IIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKK--------EIEEKI--GVENF 118
I RF+ MQGYNV + + G PI E+ K ++ E+I E+
Sbjct: 63 IARFKRMQGYNVLFPMAWHITGSPIVGIAERIKNRDPKTIWIYRDVYKVPEEILWTFEDP 122
Query: 119 IKKCKEFALNNLKIMTEQFKMLGIWMDWDNPYMTIK-----NEYIESAWFTLKRAWEKGL 173
I K F +K E F G +DW + T +++IE ++ LK EKG
Sbjct: 123 INIVKYF----MKAAKETFIRAGFSVDWSREFYTTSLFPPFSKFIEWQFWKLK---EKGY 175
Query: 174 LEKDKRVLHWCPRCETALAEHEVRGEYKLRKDPSIYVKFPV-EGKENEYLLIWTTTPWTL 232
+ K + W P T L +H++ + I +KF + E E YL T P T+
Sbjct: 176 IVKGAHRVRWDPVVGTPLGDHDLMEGEDVPILDYIIIKFELRENGEVIYLPAATLRPETV 235
Query: 233 PANLAVSAHPDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGL 292
+ +P+ YVK KV +EE WI++K K+ + + EV+EEFKG +L G
Sbjct: 236 YGVTNMWVNPNATYVKAKVRRKDKEETWIVSKEAAYKLSFQ-DREIEVIEEFKGEKLIG- 293
Query: 293 RYV------------------------------------HILMDEYPRQKEFKEKYEWAH 316
+YV H+ +++ R+ E EKY+
Sbjct: 294 KYVRNPVSGDEVIILPAEFVDPDNATGVVMSVPAHAPFDHVALEDLKRETEILEKYDIDP 353
Query: 317 RVI-------------LADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGK 363
R++ DF +EE V+ ++D E ++ +Y +G
Sbjct: 354 RIVENITYISLIKLEGYGDFPAVEE----VNKLGIKSQKDKEKLEQATKTIYKAEYHKGI 409
Query: 364 YTEGKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKI 423
+ ++G V+E I + + EKG E K +I DQWF+
Sbjct: 410 FKVPPYEGKPVQEVKEAIAKEMLEKGIAEIMYEFAEKNVISRFGNRAVIKIIHDQWFIDY 469
Query: 424 SKV--KDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWV----ISRQRYWGIPLPIWQSE 477
K+K K E++ P+ + +F+ + DW+ +R+ G PLP W E
Sbjct: 470 GNPEWKEKARKAL-ERMKILPETRRAQFEAII----DWLDKKACARKIGLGTPLP-WDPE 523
Query: 478 DGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIK 537
+V+ S + ++ +L + E KL PE L + D ++
Sbjct: 524 ----WVIESLSDSTIYMAYYTISRHINKLRQ---------EGKLDPEKLTPEFFDYIFLE 570
Query: 538 VNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKW--FYS 595
+D + ++ +GI + KE FE +P D+ G+D + F+
Sbjct: 571 EFSEDKEK-----ELEKKTGIPAEI---IHEMKEEFEYWYPLDWRCSGKDLIPNHLTFFI 622
Query: 596 QQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWA 655
+I + P + +A++G+ E G KMSKS GN++ + +E G D R Y++
Sbjct: 623 FNHVAIFREEHWP-KGIAVNGFGTLE-GQKMSKSKGNVLNFIDAIEENGADVVRLYIMSL 680
Query: 656 TNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWIL 715
+ + K V ++R+ + + + + Y N + ++ D+W+L
Sbjct: 681 AEHDSDFDWRRKEVGKLRKQIERFYELISQFAEYEVKGNVE----------LKDIDRWML 730
Query: 716 SRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYY 775
R+N I E N +E F A + + ++ DL RWY+R EG D + A Y
Sbjct: 731 HRLNKAIKETTNALEEFRTRTAVQWAFYSIMNDL-RWYLRR------TEGRDDE--AKRY 781
Query: 776 TLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREME 835
L + DV +RL+APFTP+I EE+++ L V + WP+ E+ +E +E E E
Sbjct: 782 VLRTLADVWVRLMAPFTPHICEELWEKL----GGEGFVSLAKWPEPVEEWWNETIEAEEE 837
Query: 836 FIRRIVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQLNAKEVKVGR 895
FIR ++E + AKI+ +R I T ++ K E ++ RD ++ E
Sbjct: 838 FIRSVMEDIKEIIEVAKIE---NAKRAYIYTAEDWKWKVAEVVSE-KRDFKSSME----- 888
Query: 896 VERELTIKPNFAKLGPEFKGDAKIIAKWINE 926
EL K G E AKI+ K I E
Sbjct: 889 ---ELMKDSEIRKHGKEV---AKIVQKLIKE 913
>pir||H75133 leucyl-tRNA synthetase (leus) PAB1782 - Pyrococcus abyssi (strain
Orsay) >gi|5458296|emb|CAB49785.1| (AJ248285)
leucyl-tRNA synthetase (leuS) [Pyrococcus abyssi]
Length = 967
Score = 204 bits (514), Expect = 4e-51
Identities = 238/993 (23%), Positives = 418/993 (41%), Gaps = 165/993 (16%)
Query: 9 EYDPKKLEEKVEKFWSENEIYR-KVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKD 67
E + + +EEK +K W E +++ +K+ K+ K+Y PY+SG +H+G A I D
Sbjct: 3 ELNFRAIEEKWQKRWLEAKVFEPNIKDKPKE-KKFYITVAFPYLSGHLHVGHARTYTIPD 61
Query: 68 MIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFAL 127
+I RF+ MQGYNV G+ + G PI + + K I + + K E L
Sbjct: 62 VIARFKRMQGYNVLFPMGWHITGSPI-----VGIAERIKNRDPHTIWIYRDVYKVPEEIL 116
Query: 128 NN-----------LKIMTEQFKMLGIWMDWDNPYMTIK-----NEYIESAWFTLKRAWEK 171
+K E F G +DW + T +++IE + LK EK
Sbjct: 117 WTFEDPVNIVKYFMKAAKETFIRAGFSVDWSREFYTTSLFPPFSKFIEWQFLKLK---EK 173
Query: 172 GLLEKDKRVLHWCPRCETALAEHEVRGEYKLRKDPSIYVKFPV-EGKENEYLLIWTTTPW 230
G + K + W P T L +H++ + + +KF + EG E YL T P
Sbjct: 174 GYIVKGAHRVRWDPVVGTPLGDHDLMEGEDVPILEYVIIKFELKEGDETIYLPAATLRPE 233
Query: 231 TLPANLAVSAHPDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELE 290
T+ + +P+ YVK KV+ G+EE WI++K K L + EV+EEFKG +L
Sbjct: 234 TVYGVTNMWINPNATYVKAKVKRGGKEETWIISKEAAYK-LSFQDREIEVIEEFKGEKLI 292
Query: 291 GLRYV------------------------------------HILMDEYPRQKEFKEKYEW 314
G +YV H+ +++ R+ E KY+
Sbjct: 293 G-KYVRNPVTGDEVIILPAEFVDPDNATGVVMSVPAHAPFDHVALEDLKRESEILVKYDI 351
Query: 315 AHRVI-------------LADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQ 361
R++ +F +EE V ++D E ++ +Y +
Sbjct: 352 DPRIVEEITYISLIKLEGYGEFPAVEE----VQKLGIKSQKDREKLEQATKTIYKAEYHK 407
Query: 362 GKYTEGKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFL 421
G + + G V+E I + + EKG E K +I DQWF+
Sbjct: 408 GIFKVPPYDGKPVQEVKELIAKEMMEKGIAEIMYEFAEKNVISRFGNRAVIKIIHDQWFI 467
Query: 422 KI--SKVKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWV----ISRQRYWGIPLPIWQ 475
S+ K+K K ++ YP+ + +F+ + DW+ +R+ G PLP W
Sbjct: 468 DYGNSEWKEKARKAL-ARMKIYPETRRAQFEAII----DWLDKKACARKVGLGTPLP-WD 521
Query: 476 SEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFI 535
E +V+ S + ++ L E E +L PE L + D
Sbjct: 522 PE----WVIESLSDSTIYMAYYTISRHINRLRE---------EGRLDPEKLTPEFFDYIF 568
Query: 536 IKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTK--WF 593
++ ++ + ++ +GI + KE FE +P D+ G+D + F
Sbjct: 569 LEEFSEEREK-----ELEKKTGIPAEI---IHEMKEEFEYWYPLDWRCSGKDLIPNHLTF 620
Query: 594 YSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYML 653
+ +I + P + +A++G+ E G KMSKS GN++ + +E G D R Y++
Sbjct: 621 FIFNHVAIFREEHWP-KGIAVNGFGTLE-GQKMSKSKGNVLNFIDAIEENGADVVRLYIM 678
Query: 654 WATNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKW 713
+ + K V ++RR L + + + Y + +N + + + DKW
Sbjct: 679 SLAEHDSDFDWRRKEVGKLRRQLERFYELISQFAEYEAKENVELKTI----------DKW 728
Query: 714 ILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAA 773
+L R+N I +E F A + + ++ DL RWY+R EG D + A
Sbjct: 729 LLHRLNKAIEGTTKALEEFRTRTAVQWAFYSIMNDL-RWYMRR------TEGRDDE--AK 779
Query: 774 YYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELERE 833
+ L K+ D+ +RL+APFTP+I EE+++ L V + WP+ ++ +EE+E E
Sbjct: 780 RFVLRKLADIWVRLMAPFTPHICEELWEKL----GGEGFVSLAKWPEPVDEWWNEEVEVE 835
Query: 834 MEFIRRIVEAGSAARQRAKI------------KLRYPVRRIIIE-----------TEDET 870
+FI+ ++E + AKI + ++ V ++ E +DE
Sbjct: 836 EDFIKSLIEDIKEIIEVAKIESPKRAYIYTAPEWKWKVYEVVAEKREFKSAMAELMKDEE 895
Query: 871 VKKAVERLNRILRDQLNAKEVKVGRVERELTIK 903
++K + + ++++ + + V R++ E ++
Sbjct: 896 IRKHGKEVAKLVQAIIKERAFDVKRIDEEKVLR 928
>gi|6755953 valyl-tRNA synthetase 2 [Mus musculus] >gi|3986754|gb|AAC84151.1|
(AF109905) G7A [Mus musculus]
Length = 1263
Score = 200 bits (504), Expect = 6e-50
Identities = 205/903 (22%), Positives = 364/903 (39%), Gaps = 144/903 (15%)
Query: 10 YDPKKLEEKVEKFWSENEIYRKV---KELRKDGPKYYFLD--GPPYVSGAIHLGTAWNKI 64
Y P+ +E +W ++ + P+ F+ PP V+G++HLG A
Sbjct: 299 YSPQYVEAAWYPWWERQGFFKPEYGRPSVSAPNPRGVFMMCIPPPNVTGSLHLGHALTNA 358
Query: 65 IKDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKE 124
I+D + R+ M+G PG D G+ +V VE+ L K + ++G E F+++ +
Sbjct: 359 IQDSLTRWHRMRGETTLWNPGCDHAGIATQVVVEKKL-WKERGLNRHQLGREAFLEEVWK 417
Query: 125 FALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWC 184
+ + Q K LG +DWD T+ + + R E+G++ + R+++W
Sbjct: 418 WKAEKGDRIYHQLKKLGSSLDWDRACFTMDPKLSATVTEAFVRLHEEGVIYRSTRLVNWS 477
Query: 185 PRCETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDY 244
+A+++ EV +K+ + PV G + + + + VS
Sbjct: 478 CTLNSAISDIEVD-----KKELTGRTLLPVPGYKEK-----------VEFGVLVS----- 516
Query: 245 DYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPR 304
KV+ + +E ++A ++ +LG++ V ++ + + L+G VH +
Sbjct: 517 --FAYKVQGSDSDEEVVVATTRIETMLGDVAVAVH-PKDPRYQHLKGKCVVHPFLSR--- 570
Query: 305 QKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKY 364
+ ++ DFV +E GTG V P H + D+EVGQ++ L S +D +G
Sbjct: 571 ----------SLPIVFDDFVDMEFGTGAVKITPAHDQNDYEVGQRHRLEAISIMDSKGAL 620
Query: 365 --TEGKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLK 422
+ G+ EA ++ L+E+G + P C R K + QW+++
Sbjct: 621 INVPPPFLGLPRFEARKAVLAALKERGLFRGVKDNPMVVPLCNRSKDVVEPLLRPQWYVR 680
Query: 423 ---ISKVKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIW----- 474
+++ + D ++ P+ + + + + + DW ISRQ +WG +P +
Sbjct: 681 CGEMAQAASAAVTRGDLRI--LPEAHQRTWHSWMDNIRDWCISRQLWWGHRIPAYFITVH 738
Query: 475 -------QSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLH 527
+ DG +V G E E + V +K+
Sbjct: 739 DPAVPPGEDPDGRYWVSGR---------------TEAEAREKAAREFGVSPDKI------ 777
Query: 528 RPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGED 587
+++ +DV+D WF SG+ ++ G+P E +P + G D
Sbjct: 778 --------------SLQQDEDVLDTWFSSGLFPFSIFGWPNQSEDLSVFYPGTLLETGHD 823
Query: 588 QVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEV-------- 639
+ W + +P+R V +H V D G KMSKSLGN+I P +V
Sbjct: 824 ILFFWVARMVMLGLKLTGKLPFREVYLHAIVRDAHGRKMSKSLGNVIDPLDVIHGVSLQG 883
Query: 640 --------------VERA---------------GRDTFRFYMLWATNPWENLKFSWKGVE 670
VE+A G D RF + T+ ++ +
Sbjct: 884 LYDQLLNSNLDPSEVEKAKEGQKADFPAGIPECGTDALRFGLCAYTSQGRDINLDVNRIL 943
Query: 671 QVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISEVENGIE 730
R N LWN A + F P + E D+WI SR+ + G +
Sbjct: 944 GYRHFCNKLWNATKFALRGLG-KGFVPSATSKPEGHESLVDRWIRSRLTEAVRLSNEGFQ 1002
Query: 731 SFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLA---AYYTLWKVFDVLLRL 787
++ T A Y+F + +L Y+ ++ L D++A A TL+ DV LRL
Sbjct: 1003 AYDFPAITTAQYSFWLYELCDVYLECLKPVL----NGVDQVAAECARQTLYTCLDVGLRL 1058
Query: 788 LAPFTPYIAEEIYQNLIRPFTNV-ESVHMLDWPKVDEKA-IDEELEREMEFIRRIVEAGS 845
L+PF P++ EE++Q L R S+ + +P+ E + D E E +E I A
Sbjct: 1059 LSPFMPFVTEELFQRLPRRTPKAPASLCVTPYPEPSECSWKDPEAEAALELALSITRAVR 1118
Query: 846 AAR 848
+ R
Sbjct: 1119 SLR 1121
>pir||E82913 valyl-tRNA synthetase UU267 [imported] - Ureaplasma urealyticum
>gi|6899238|gb|AAF30676.1|AE002123_9 (AE002123)
valyl-tRNA synthetase [Ureaplasma urealyticum]
Length = 874
Score = 200 bits (503), Expect = 8e-50
Identities = 209/897 (23%), Positives = 389/897 (43%), Gaps = 146/897 (16%)
Query: 2 IKEPEFREYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAW 61
+K+ ++Y K++E FW EN +++ ++ + + PP V+G +H+G A+
Sbjct: 1 MKKKLSKKYSFKEVEANKLLFWQENNLFKA--QINSTKKPFTIVLPPPNVTGHLHIGHAY 58
Query: 62 NKIIKDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKK 121
+ + D+++R++ ++ GYD +P G+ T+ + E+ + V
Sbjct: 59 DFTLSDILMRYKKLK--------GYDSFIIP----GTDHAGIATQTKFEKNLKVNA---- 102
Query: 122 CKEFALNNLKIMTEQF-KMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGL-LEKDKR 179
N + E F + L IW D + YI W L GL L+
Sbjct: 103 ----QTNRFNLGRELFLEKLKIWKDE-------QINYIHKQWNAL------GLGLDYSNY 145
Query: 180 VLHWCPRCETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVS 239
+ P + E V K+ + IY ++ L+ W T +N+ V
Sbjct: 146 LFTLDPIVVQTVREVFV----KMFNEHIIY--------RDKKLVNWDIQLKTAISNIEV- 192
Query: 240 AHPDYDYVKVKVEF--NGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHI 297
H + + +++ ++++ ++A + + + G+ K V+ + RY H+
Sbjct: 193 IHKEVEQKLYYIKYLSQDQKDFVVVATSRPETMFGD---KYLVINP------KDKRYFHL 243
Query: 298 LMDEYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSP 357
+ E VIL D++ +E GTG++ P H D+E+ +K+ L + +
Sbjct: 244 HNKIFINPINNIEM-----TVILDDYIDIEFGTGVMKCTPAHDFNDYELAKKHNLEIINI 298
Query: 358 LDDQGKYTE--GKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRA 415
++ G E G++KG+ EA II+ L++ +L+K R +
Sbjct: 299 MNADGTLNEKCGEFKGLDRLEARSLIIDKLQKNNHLLKVESYRTSVGFSERTNEIVEPYL 358
Query: 416 TDQWFLKI-SKVKDKIIKEND--EKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLP 472
+ QWF+K+ S +KD I ++D KV +YP+ ++++ DW ISRQ +WG +P
Sbjct: 359 SHQWFIKMDSLIKDTIKMQDDCNNKVDFYPNRFNKTLLTWLKNTEDWCISRQLWWGHQIP 418
Query: 473 IWQSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIE-EKLGPEDLHRPYV 531
+W Y +K I + + P+DL
Sbjct: 419 VW-----------------------------------YHKKTNQIYCDTIPPKDLENWIQ 443
Query: 532 DAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTK 591
D +DV+D WF SG+ + + N F++ +P IV G D +
Sbjct: 444 D--------------EDVLDTWFSSGMWPLLTTKWNYNSHFFDRYFPTSLIVTGMDILFF 489
Query: 592 WFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFY 651
W S + P++ V +HG + D +G KMSKSLGN I P +++++ G D R +
Sbjct: 490 WVSRMMNFSQYLVEKKPFKDVLIHGLIRDSQGRKMSKSLGNGIDPFDIIDKYGLDAMRLF 549
Query: 652 MLWATNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREED 711
T E+L FS + + LN +WN+ A +LD + D F + +
Sbjct: 550 FASCTTIGEDLNFSTERLGANWNYLNKIWNI---AKYIENLDEINDNLNFEDVDKFCDVN 606
Query: 712 KWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYV---RLIRKRLWVEGEDP 768
KWIL+ ++ L E+ ++ + L AT+ LY+F+ + +Y+ +++ + L ++ E
Sbjct: 607 KWILTELSKLTLEINKNMDKYNLVVATKYLYDFIWNTFASYYLEYTKVLLQDLTLKNE-- 664
Query: 769 DKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVD---EKA 825
T+ VF+ +L +L PF P I+EEI+ L + TN S+ + ++P ++ E
Sbjct: 665 ----TIKTIRYVFNKILIMLQPFAPNISEEIWLCLNQ--TN-NSILLQEYPIINFEFETI 717
Query: 826 IDEELEREMEFIRRIVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRIL 882
I +++ + + IR++ R I R + +I D K ++ +N +L
Sbjct: 718 IIDKIAKIILEIRKL-------RLEENINNRINLCFELISPNDAFYKSKIKLVNLLL 767
>gb|AAD26531.1|AF087141_1 (AF087141) valyl-tRNA synthetase [Mus musculus]
>gi|4590330|gb|AAD26532.1|AF087680_1 (AF087680)
valyl-tRNA synthetase [Mus musculus]
Length = 1263
Score = 198 bits (499), Expect = 2e-49
Identities = 204/903 (22%), Positives = 363/903 (39%), Gaps = 144/903 (15%)
Query: 10 YDPKKLEEKVEKFWSENEIYRKV---KELRKDGPKYYFLD--GPPYVSGAIHLGTAWNKI 64
Y P+ +E +W ++ + P+ F+ PP V+G++HLG A
Sbjct: 299 YSPQYVEAAWYPWWERQGFFKPEYGRPSVSAPNPRGVFMMCIPPPNVTGSLHLGHALTNA 358
Query: 65 IKDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKE 124
I+D + R+ M+G PG D G+ +V VE+ L K + ++G E F+++ +
Sbjct: 359 IQDSLTRWHRMRGETTLWNPGCDHAGIATQVVVEKKL-WKERGLNRHQLGREAFLEEVWK 417
Query: 125 FALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWC 184
+ + Q K LG +DWD T+ + + R E+G++ + R+++W
Sbjct: 418 WKAEKGDRIYHQLKKLGSSLDWDRACFTMDPKLSATVTEAFVRLHEEGVIYRSTRLVNWS 477
Query: 185 PRCETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDY 244
+A+++ EV +K+ + PV G + + + + VS
Sbjct: 478 CTLNSAISDIEVD-----KKELTGRTLLPVPGYKEK-----------VEFGVLVS----- 516
Query: 245 DYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPR 304
KV+ + +E ++A ++ +LG++ V ++ + + L+G VH +
Sbjct: 517 --FAYKVQGSDSDEEVVVATTRIETMLGDVAVAVH-PKDPRYQHLKGKCVVHPFLSR--- 570
Query: 305 QKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKY 364
+ ++ DFV +E GTG V P H + D+EVGQ++ L S +D +G
Sbjct: 571 ----------SLPIVFDDFVDMEFGTGAVKITPAHDQNDYEVGQRHRLEAISIMDSKGAL 620
Query: 365 --TEGKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLK 422
+ G+ EA ++ L+E+G + P C R K + QW+++
Sbjct: 621 INVPPPFLGLPRFEARKAVLAALKERGLFRGVKDNPMVVPLCNRSKDVVEPLLRPQWYVR 680
Query: 423 ---ISKVKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIW----- 474
+++ + D ++ P+ + + + + + DW ISRQ +WG +P +
Sbjct: 681 CGEMAQAASAAVTRGDLRI--LPEAHQRTWHSWMDNIRDWCISRQLWWGHRIPAYFITVH 738
Query: 475 -------QSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLH 527
+ DG +V G E E + V +K+
Sbjct: 739 DPAVPPGEDPDGRYWVSGR---------------TEAEAREKAAREFGVSPDKI------ 777
Query: 528 RPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGED 587
+++ +DV+D WF SG+ ++ G+P E +P + G D
Sbjct: 778 --------------SLQQDEDVLDTWFSSGLFPFSIFGWPNQSEDLSVFYPGTLLETGHD 823
Query: 588 QVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEV-------- 639
+ W + +P+R V +H V D G KMSKSLGN+I P +V
Sbjct: 824 ILFFWVARMVMLGLKLTGKLPFREVYLHAIVRDAHGRKMSKSLGNVIDPLDVIHGVSLQG 883
Query: 640 --------------VERA---------------GRDTFRFYMLWATNPWENLKFSWKGVE 670
VE+A G D RF + T+ ++ +
Sbjct: 884 LYDQLLNSNLDPSEVEKAKEGQKADFPAGIPECGTDALRFGLCAYTSQGRDINLDVNRIL 943
Query: 671 QVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISEVENGIE 730
R N LWN + F P + E D+WI SR+ + G +
Sbjct: 944 GYRHFCNKLWNATKFRLRGLG-KGFVPSATSKPEGHESLVDRWIRSRLTEAVRLSNEGFQ 1002
Query: 731 SFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLA---AYYTLWKVFDVLLRL 787
++ T A Y+F + +L Y+ ++ L D++A A TL+ DV LRL
Sbjct: 1003 AYDFPAITTAQYSFWLYELCDVYLECLKPVL----NGVDQVAAECARQTLYTCLDVGLRL 1058
Query: 788 LAPFTPYIAEEIYQNLIRPFTNV-ESVHMLDWPKVDEKA-IDEELEREMEFIRRIVEAGS 845
L+PF P++ EE++Q L R S+ + +P+ E + D E E +E I A
Sbjct: 1059 LSPFMPFVTEELFQRLPRRTPKAPASLCVTPYPEPSECSWKDPEAEAALELALSITRAVR 1118
Query: 846 AAR 848
+ R
Sbjct: 1119 SLR 1121
>gb|AAA81332.1| (M98326) valyl-tRNA synthetase [Homo sapiens]
Length = 1063
Score = 196 bits (492), Expect = 2e-48
Identities = 212/932 (22%), Positives = 364/932 (38%), Gaps = 202/932 (21%)
Query: 10 YDPKKLEEKVEKFWSENEIYRKV---KELRKDGPKYYFLD--GPPYVSGAIHLGTAWNKI 64
Y P+ +E +W + ++ + P+ F+ PP V+G++HLG A
Sbjct: 100 YSPRYVEAAWYPWWEQQGFFKPEYGRPNVSAGNPRGVFMMCIPPPNVTGSLHLGHALTNA 159
Query: 65 IKDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKE 124
I+D + R+ M+G PG D G+ +V VE+ L + + ++G E F+++ +
Sbjct: 160 IQDSLTRWHRMRGETTLWNPGCDHAGIATQVVVEKKL-WREQGLSRHQLGREAFLQEVWK 218
Query: 125 FALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWC 184
+ + Q K LG +DWD T+ + + R E+G++ + R+++W
Sbjct: 219 WKEEKGDRIYHQLKKLGSSLDWDRACFTMDPKLSAAVTEAFVRLHEEGIIYRSTRLVNWS 278
Query: 185 PRCETALAEHEVRGE------------YKLRKDPSIYVKF--PVEGKE-NEYLLIWTTTP 229
+A+++ EV + YK + + + V F V+G + +E +++ TT
Sbjct: 279 CTLNSAISDIEVDKKELTGRTLLSVPGYKEKVEFGVLVSFAYKVQGSDSDEEVVVATTRI 338
Query: 230 WTLPANLAVSAHPD---YDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKG 286
T+ ++AV+ HP Y ++K K V+ F
Sbjct: 339 ETMLGDVAVAVHPKDTRYQHLKGK----------------------------NVIHPFLS 370
Query: 287 RELEGLRYVHILMDEYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEV 346
R L ++ +FV ++ GTG V P H + D+EV
Sbjct: 371 RSLP---------------------------IVFDEFVDMDFGTGAVKITPAHDQNDYEV 403
Query: 347 GQKYGLPVYSPLDDQGKY--TEGKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHC 404
GQ++GL S +D +G + G+ EA ++ L+E+G + P C
Sbjct: 404 GQRHGLEAISIMDSRGALINVPPPFLGLPRFEARKAVLVALKERGLFRGIEDNPMVVPLC 463
Query: 405 WRCKTPLIFRATDQWFLKISKVKD-----------KIIKENDEKVTWYPDWVKIRFDNGV 453
R K + QW+++ ++ +I+ E ++ TW+ IR
Sbjct: 464 NRSKDVVEPLLRPQWYVRCGEMAQAASAAVTRGDLRILPEAHQR-TWHAWMDNIR----- 517
Query: 454 RDSGDWVISRQRYWGIPLPIW------------QSEDGEIYVVGSWRELVELAVAIEVNG 501
+W ISRQ +WG +P + + DG +V G
Sbjct: 518 ----EWCISRQLWWGHRIPAYFVTVSDPAVPPGEDPDGRYWVSGR--------------- 558
Query: 502 ERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASW 561
E E ++ V +K+ +++ +DV+D WF SG+
Sbjct: 559 NEAEAREKAAKEFGVSPDKI--------------------SLQQDEDVLDTWFSSGLFPL 598
Query: 562 ASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDE 621
+ LG+P E +P + G D + W + +P+R V +H V D
Sbjct: 599 SILGWPNQSEDLSVFYPGTLLETGHDILFFWVARMVMLGLKLTGRLPFREVYLHAIVRDA 658
Query: 622 KGDKMSKSLGNIIRPEEV----------------------VERA---------------G 644
G KMSKSLGN+I P +V VE+A G
Sbjct: 659 HGRKMSKSLGNVIDPLDVIYGISLQGLHNQLLNSNLDPSEVEKAKEGQKADFPAGIPECG 718
Query: 645 RDTFRFYMLWATNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDE 704
D RF + + ++ + R N LWN A + F P +P
Sbjct: 719 TDALRFGLCAYMSQGRDINLDVNRILGYRHFCNKLWNATKFALRGLG-KGFVP---SPTS 774
Query: 705 LPFREE---DKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRL 761
P E D+WI SR+ + G +++ T A Y+F + +L Y+ ++ L
Sbjct: 775 QPGGHESLVDRWIRSRLTEAVRLSNQGFQAYDFPAVTTAQYSFWLYELCDVYLECLKPVL 834
Query: 762 WVEGEDPDKLA---AYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNV-ESVHMLD 817
D++A A TL+ DV LRLL+PF P++ EE++Q L R S+ +
Sbjct: 835 ----NGVDQVAAECARQTLYTCLDVGLRLLSPFIPFVTEELFQRLPRRMPQAPPSLCVTP 890
Query: 818 WPKVDEKA-IDEELEREMEFIRRIVEAGSAAR 848
+P+ E + D E E +E I A + R
Sbjct: 891 YPEPSECSWKDPEAEAALELALSITRAVRSLR 922
>sp|P26640|SYV_HUMAN VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
Length = 1263
Score = 196 bits (492), Expect = 2e-48
Identities = 212/932 (22%), Positives = 364/932 (38%), Gaps = 202/932 (21%)
Query: 10 YDPKKLEEKVEKFWSENEIYRKV---KELRKDGPKYYFLD--GPPYVSGAIHLGTAWNKI 64
Y P+ +E +W + ++ + P+ F+ PP V+G++HLG A
Sbjct: 300 YSPRYVEAAWYPWWEQQGFFKPEYGRPNVSAGNPRGVFMMCIPPPNVTGSLHLGHALTNA 359
Query: 65 IKDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKE 124
I+D + R+ M+G PG D G+ +V VE+ L + + ++G E F+++ +
Sbjct: 360 IQDSLTRWHRMRGETTLWNPGCDHAGIATQVVVEKKL-WREQGLSRHQLGREAFLQEVWK 418
Query: 125 FALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWC 184
+ + Q K LG +DWD T+ + + R E+G++ + R+++W
Sbjct: 419 WKEEKGDRIYHQLKKLGSSLDWDRACFTMDPKLSAAVTEAFVRLHEEGIIYRSTRLVNWS 478
Query: 185 PRCETALAEHEVRGE------------YKLRKDPSIYVKF--PVEGKE-NEYLLIWTTTP 229
+A+++ EV + YK + + + V F V+G + +E +++ TT
Sbjct: 479 CTLNSAISDIEVDKKELTGRTLLSVPGYKEKVEFGVLVSFAYKVQGSDSDEEVVVATTRI 538
Query: 230 WTLPANLAVSAHPD---YDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKG 286
T+ ++AV+ HP Y ++K K V+ F
Sbjct: 539 ETMLGDVAVAVHPKDTRYQHLKGK----------------------------NVIHPFLS 570
Query: 287 RELEGLRYVHILMDEYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEV 346
R L ++ +FV ++ GTG V P H + D+EV
Sbjct: 571 RSLP---------------------------IVFDEFVDMDFGTGAVKITPAHDQNDYEV 603
Query: 347 GQKYGLPVYSPLDDQGKY--TEGKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHC 404
GQ++GL S +D +G + G+ EA ++ L+E+G + P C
Sbjct: 604 GQRHGLEAISIMDSRGALINVPPPFLGLPRFEARKAVLVALKERGLFRGIEDNPMVVPLC 663
Query: 405 WRCKTPLIFRATDQWFLKISKVKD-----------KIIKENDEKVTWYPDWVKIRFDNGV 453
R K + QW+++ ++ +I+ E ++ TW+ IR
Sbjct: 664 NRSKDVVEPLLRPQWYVRCGEMAQAASAAVTRGDLRILPEAHQR-TWHAWMDNIR----- 717
Query: 454 RDSGDWVISRQRYWGIPLPIW------------QSEDGEIYVVGSWRELVELAVAIEVNG 501
+W ISRQ +WG +P + + DG +V G
Sbjct: 718 ----EWCISRQLWWGHRIPAYFVTVSDPAVPPGEDPDGRYWVSGR--------------- 758
Query: 502 ERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASW 561
E E ++ V +K+ +++ +DV+D WF SG+
Sbjct: 759 NEAEAREKAAKEFGVSPDKI--------------------SLQQDEDVLDTWFSSGLFPL 798
Query: 562 ASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDE 621
+ LG+P E +P + G D + W + +P+R V +H V D
Sbjct: 799 SILGWPNQSEDLSVFYPGTLLETGHDILFFWVARMVMLGLKLTGRLPFREVYLHAIVRDA 858
Query: 622 KGDKMSKSLGNIIRPEEV----------------------VERA---------------G 644
G KMSKSLGN+I P +V VE+A G
Sbjct: 859 HGRKMSKSLGNVIDPLDVIYGISLQGLHNQLLNSNLDPSEVEKAKEGQKADFPAGIPECG 918
Query: 645 RDTFRFYMLWATNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDE 704
D RF + + ++ + R N LWN A + F P +P
Sbjct: 919 TDALRFGLCAYMSQGRDINLDVNRILGYRHFCNKLWNATKFALRGLG-KGFVP---SPTS 974
Query: 705 LPFREE---DKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRL 761
P E D+WI SR+ + G +++ T A Y+F + +L Y+ ++ L
Sbjct: 975 QPGGHESLVDRWIRSRLTEAVRLSNQGFQAYDFPAVTTAQYSFWLYELCDVYLECLKPVL 1034
Query: 762 WVEGEDPDKLA---AYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNV-ESVHMLD 817
D++A A TL+ DV LRLL+PF P++ EE++Q L R S+ +
Sbjct: 1035 ----NGVDQVAAECARQTLYTCLDVGLRLLSPFIPFVTEELFQRLPRRMPQAPPSLCVTP 1090
Query: 818 WPKVDEKA-IDEELEREMEFIRRIVEAGSAAR 848
+P+ E + D E E +E I A + R
Sbjct: 1091 YPEPSECSWKDPEAEAALELALSITRAVRSLR 1122
>gi|5454158 valyl-tRNA synthetase 2 [Homo sapiens] >gi|11417740|ref|XP_004185.1|
valyl-tRNA synthetase 2 [Homo sapiens]
>gi|4529896|gb|AAD21819.1| (AF134726) G7A [Homo sapiens]
Length = 1264
Score = 195 bits (491), Expect = 2e-48
Identities = 212/932 (22%), Positives = 364/932 (38%), Gaps = 202/932 (21%)
Query: 10 YDPKKLEEKVEKFWSENEIYRKV---KELRKDGPKYYFLD--GPPYVSGAIHLGTAWNKI 64
Y P+ +E +W + ++ + P+ F+ PP V+G++HLG A
Sbjct: 300 YSPRYVEAAWYPWWEQQGFFKPEYGRPNVSAANPRGVFMMCIPPPNVTGSLHLGHALTNA 359
Query: 65 IKDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKE 124
I+D + R+ M+G PG D G+ +V VE+ L + + ++G E F+++ +
Sbjct: 360 IQDSLTRWHRMRGETTLWNPGCDHAGIATQVVVEKKL-WREQGLSRHQLGREAFLQEVWK 418
Query: 125 FALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWC 184
+ + Q K LG +DWD T+ + + R E+G++ + R+++W
Sbjct: 419 WKEEKGDRIYHQLKKLGSSLDWDRACFTMDPKLSAAVTEAFVRLHEEGIIYRSTRLVNWS 478
Query: 185 PRCETALAEHEVRGE------------YKLRKDPSIYVKF--PVEGKE-NEYLLIWTTTP 229
+A+++ EV + YK + + + V F V+G + +E +++ TT
Sbjct: 479 CTLNSAISDIEVDKKELTGRTLLSVPGYKEKVEFGVLVSFAYKVQGSDSDEEVVVATTRI 538
Query: 230 WTLPANLAVSAHPD---YDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKG 286
T+ ++AV+ HP Y ++K K V+ F
Sbjct: 539 ETMLGDVAVAVHPKDTRYQHLKGK----------------------------NVIHPFLS 570
Query: 287 RELEGLRYVHILMDEYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEV 346
R L ++ +FV ++ GTG V P H + D+EV
Sbjct: 571 RSLP---------------------------IVFDEFVDMDFGTGAVKITPAHDQNDYEV 603
Query: 347 GQKYGLPVYSPLDDQGKY--TEGKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHC 404
GQ++GL S +D +G + G+ EA ++ L+E+G + P C
Sbjct: 604 GQRHGLEAISIMDSRGALINVPPPFLGLPRFEARKAVLVALKERGLFRGIEDNPMVVPLC 663
Query: 405 WRCKTPLIFRATDQWFLKISKVKD-----------KIIKENDEKVTWYPDWVKIRFDNGV 453
R K + QW+++ ++ +I+ E ++ TW+ IR
Sbjct: 664 NRSKDVVEPLLRPQWYVRCGEMAQAASAAVTRGDLRILPEAHQR-TWHAWMDNIR----- 717
Query: 454 RDSGDWVISRQRYWGIPLPIW------------QSEDGEIYVVGSWRELVELAVAIEVNG 501
+W ISRQ +WG +P + + DG +V G
Sbjct: 718 ----EWCISRQLWWGHRIPAYFVTVSDPAVPPGEDPDGRYWVSGR--------------- 758
Query: 502 ERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASW 561
E E ++ V +K+ +++ +DV+D WF SG+
Sbjct: 759 NEAEAREKAAKEFGVSPDKI--------------------SLQQDEDVLDTWFSSGLFPL 798
Query: 562 ASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDE 621
+ LG+P E +P + G D + W + +P+R V +H V D
Sbjct: 799 SILGWPNQSEDLSVFYPGTLLETGHDILFFWVARMVMLGLKLTGRLPFREVYLHAIVRDA 858
Query: 622 KGDKMSKSLGNIIRPEEV----------------------VERA---------------G 644
G KMSKSLGN+I P +V VE+A G
Sbjct: 859 HGRKMSKSLGNVIDPLDVIYGISLQGLHNQLLNSNLDPSEVEKAKEGQKADFPAGIPECG 918
Query: 645 RDTFRFYMLWATNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDE 704
D RF + + ++ + R N LWN A + F P +P
Sbjct: 919 TDALRFGLCAYMSQGRDINLDVNRILGYRHFCNKLWNATKFALRGLG-KGFVP---SPTS 974
Query: 705 LPFREE---DKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRL 761
P E D+WI SR+ + G +++ T A Y+F + +L Y+ ++ L
Sbjct: 975 QPGGHESLVDRWIRSRLTEAVRLSNQGFQAYDFPAVTTAQYSFWLYELCDVYLECLKPVL 1034
Query: 762 WVEGEDPDKLA---AYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNV-ESVHMLD 817
D++A A TL+ DV LRLL+PF P++ EE++Q L R S+ +
Sbjct: 1035 ----NGVDQVAAECARQTLYTCLDVGLRLLSPFMPFVTEELFQRLPRRMPQAPPSLCVTP 1090
Query: 818 WPKVDEKA-IDEELEREMEFIRRIVEAGSAAR 848
+P+ E + D E E +E I A + R
Sbjct: 1091 YPEPSECSWKDPEAEAALELALSITRAVRSLR 1122
>pir||A64379 isoleucine--tRNA ligase (EC 6.1.1.5) - Methanococcus jannaschii
Length = 942
Score = 194 bits (488), Expect = 4e-48
Identities = 245/1025 (23%), Positives = 419/1025 (39%), Gaps = 209/1025 (20%)
Query: 11 DPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMII 70
D K++E+K +K W E +I+ + D K++ PY++G +H G I +++
Sbjct: 6 DFKEIEKKWQKRWEEAKIFEANPD---DREKFFITAAFPYLNGVLHAGHLRTFTIPEVVA 62
Query: 71 RFRTMQGYNVWRQPGYDMHGLPI----------------------EVKVEQALGLKTKKE 108
RF+ M+ NV GY + G PI + E+ L L T ++
Sbjct: 63 RFQRMKNKNVLWTFGYHVTGTPILGLAELIKNRDEKTIWAYTELHGIPKEELLELTTPEK 122
Query: 109 IEEKIGVENFIKKCKEFALNNLKIMTEQFKMLGIWMDWDNPYMT---IKNEYIESAWFTL 165
I VE F KK +E FK +G +DW + T + N++IE + L
Sbjct: 123 I-----VEYFSKKAEE-----------AFKRMGFSLDWRRNFKTDDKVFNKFIEWQFHKL 166
Query: 166 KRAWEKGLLEKDKRVLHWCPRCETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIW 225
K EKGL+ K + +CPRC+ + +H++ I +KF E + + +
Sbjct: 167 K---EKGLIVKGSHPVRYCPRCDNPVEDHDILVGENATLVEYILIKFTTE--DGCIMPMA 221
Query: 226 TTTPWTLPANLAVSAHPDYDYVKVKVEFNGREE---------YWILAKALVDKVLGEIGV 276
T P T+ V +P+ YVK KV E WI+AK +K+ +
Sbjct: 222 TLRPETVFGVTNVWVNPEATYVKAKVYLEKETENGIXLIENGIWIMAKECAEKLKHQ-DR 280
Query: 277 KGEVVEEFKGRELEGLRYVH-ILMDEYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHT 335
K E++EEFKG +L + + + E P ++ A FV GTG V +
Sbjct: 281 KIEIIEEFKGEQLINKKVKNPVTGKEVP--------------ILPAKFVKTNIGTGCVMS 326
Query: 336 APGHGEEDF-----------------------------EVGQKYGLP------------- 353
P H D+ E+ +K G+
Sbjct: 327 VPAHAPYDYIALRDLGLVDEIGLIPLINVPGYGKYPAKEIVEKMGIKSQEEEDKLEEATK 386
Query: 354 -VYSPLDDQGKYTEG--KWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTP 410
+Y +G E ++GI V+E K+ + L +KG E + C RC TP
Sbjct: 387 KIYKDEFHKGVLNENCLDYEGIPVREIKDKLTKDLIDKGLAEIMYEFSEEKVIC-RCGTP 445
Query: 411 LIFRATD-QWFLKISKVKDKIIKEND-EKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWG 468
I + QWF+K S K K + +K+ + P+ ++ F + D R+R G
Sbjct: 446 CIVKMVKGQWFIKYSDEKWKELAHKCIDKMRFIPENLRQVFHEKIDWMKDKACVRRRGLG 505
Query: 469 IPLPIWQSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHR 528
P E+G + IE + P Y + + + PE L
Sbjct: 506 TKFPF---EEGWV---------------IESLSDSTIYPAYYTVAKYINQHNIKPEQLTL 547
Query: 529 PYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQ 588
D + GK DV + ++GI G + F +P D+ +D
Sbjct: 548 ELFDYVFL---GKG-----DVDKIAKETGIPKDIIEGMRKE---FIYYYPVDWRCSAKDL 596
Query: 589 VTKW--FYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRD 646
+ FY +I + P R + ++GYV E G K+SKS G ++ EV E+ G D
Sbjct: 597 IPNHLTFYIFNHVAIFPEEFWP-RGIVVNGYVTIE-GKKLSKSKGPVLPVLEVAEKFGAD 654
Query: 647 TFRFYMLWATNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELP 706
RFY+ ++ +K +E +++L L Y+ R+ E
Sbjct: 655 VGRFYITTCAELPQDADIKFKEMENTKKVLERL---------YLFAKEIAERRGETGE-E 704
Query: 707 FREEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGE 766
F DKW+LSR+ + + + +E+F L KA LY +++DL +WY R + V
Sbjct: 705 FSYIDKWLLSRLYKAVKQYDEYMENFELRKAGILLYQ-LLDDL-KWYRRRGGNNIRV--- 759
Query: 767 DPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAI 826
L + +V+++L+ PFTP++ EE+++ L + V + +P+V E+ I
Sbjct: 760 ----------LEEFLEVIIKLMMPFTPHLCEEMWEILGKE----GFVSLAKFPEVKEEFI 805
Query: 827 DEELEREMEFIRRIVEAGSAARQRAKIK-----------LRYPVRRIIIETEDETVKKAV 875
++E+E+ E+++ ++E AK++ +Y + +II E E +T+K+ +
Sbjct: 806 NDEIEKGEEYLKAVMEDIKEIINVAKVQPKRIYLYTADDWKYEILKIIKENEGKTIKELM 865
Query: 876 ERLNRILRDQLNAKEVKVGRVERELTIKPNFAKLGPEFKGDAKIIAKWINENGRELYEKG 935
+ + + KE+ + KL E + +++ EN +E +K
Sbjct: 866 PIIMKNPEFRKYGKEIP--------KLVNQLIKLNAEIINEVEVL-----ENAKEFLKK- 911
Query: 936 ELTVE 940
E+ VE
Sbjct: 912 EVGVE 916
>sp|Q58050|SYL_METJA LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS)
>gi|2826301|gb|AAB98628.1| (U67511) leucyl-tRNA
synthetase (leuS) [Methanococcus jannaschii]
Length = 942
Score = 194 bits (488), Expect = 4e-48
Identities = 245/1025 (23%), Positives = 419/1025 (39%), Gaps = 209/1025 (20%)
Query: 11 DPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMII 70
D K++E+K +K W E +I+ + D K++ PY++G +H G I +++
Sbjct: 6 DFKEIEKKWQKRWEEAKIFEANPD---DREKFFITAAFPYLNGVLHAGHLRTFTIPEVVA 62
Query: 71 RFRTMQGYNVWRQPGYDMHGLPI----------------------EVKVEQALGLKTKKE 108
RF+ M+ NV GY + G PI + E+ L L T ++
Sbjct: 63 RFQRMKNKNVLWTFGYHVTGTPILGLAELIKNRDEKTIWAYTELHGIPKEELLELTTPEK 122
Query: 109 IEEKIGVENFIKKCKEFALNNLKIMTEQFKMLGIWMDWDNPYMT---IKNEYIESAWFTL 165
I VE F KK +E FK +G +DW + T + N++IE + L
Sbjct: 123 I-----VEYFSKKAEE-----------AFKRMGFSLDWRRNFKTDDKVFNKFIEWQFHKL 166
Query: 166 KRAWEKGLLEKDKRVLHWCPRCETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIW 225
K EKGL+ K + +CPRC+ + +H++ I +KF E + + +
Sbjct: 167 K---EKGLIVKGSHPVRYCPRCDNPVEDHDILVGENATLVEYILIKFTTE--DGCIMPMA 221
Query: 226 TTTPWTLPANLAVSAHPDYDYVKVKVEFNGREE---------YWILAKALVDKVLGEIGV 276
T P T+ V +P+ YVK KV E WI+AK +K+ +
Sbjct: 222 TLRPETVFGVTNVWVNPEATYVKAKVYLEKETENGIELIENGIWIMAKECAEKLKHQ-DR 280
Query: 277 KGEVVEEFKGRELEGLRYVH-ILMDEYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHT 335
K E++EEFKG +L + + + E P ++ A FV GTG V +
Sbjct: 281 KIEIIEEFKGEQLINKKVKNPVTGKEVP--------------ILPAKFVKTNIGTGCVMS 326
Query: 336 APGHGEEDF-----------------------------EVGQKYGLP------------- 353
P H D+ E+ +K G+
Sbjct: 327 VPAHAPYDYIALRDLGLVDEIGLIPLINVPGYGKYPAKEIVEKMGIKSQEEEDKLEEATK 386
Query: 354 -VYSPLDDQGKYTEG--KWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTP 410
+Y +G E ++GI V+E K+ + L +KG E + C RC TP
Sbjct: 387 KIYKDEFHKGVLNENCLDYEGIPVREIKDKLTKDLIDKGLAEIMYEFSEEKVIC-RCGTP 445
Query: 411 LIFRATD-QWFLKISKVKDKIIKEND-EKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWG 468
I + QWF+K S K K + +K+ + P+ ++ F + D R+R G
Sbjct: 446 CIVKMVKGQWFIKYSDEKWKELAHKCIDKMRFIPENLRQVFHEKIDWMKDKACVRRRGLG 505
Query: 469 IPLPIWQSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHR 528
P E+G + IE + P Y + + + PE L
Sbjct: 506 TKFPF---EEGWV---------------IESLSDSTIYPAYYTVAKYINQHNIKPEQLTL 547
Query: 529 PYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQ 588
D + GK DV + ++GI G + F +P D+ +D
Sbjct: 548 ELFDYVFL---GKG-----DVDKIAKETGIPKDIIEGMRKE---FIYYYPVDWRCSAKDL 596
Query: 589 VTKW--FYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRD 646
+ FY +I + P R + ++GYV E G K+SKS G ++ EV E+ G D
Sbjct: 597 IPNHLTFYIFNHVAIFPEEFWP-RGIVVNGYVTIE-GKKLSKSKGPVLPVLEVAEKFGAD 654
Query: 647 TFRFYMLWATNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELP 706
RFY+ ++ +K +E +++L L Y+ R+ E
Sbjct: 655 VGRFYITTCAELPQDADIKFKEMENTKKVLERL---------YLFAKEIAERRGETGE-E 704
Query: 707 FREEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGE 766
F DKW+LSR+ + + + +E+F L KA LY +++DL +WY R + V
Sbjct: 705 FSYIDKWLLSRLYKAVKQYDEYMENFELRKAGILLYQ-LLDDL-KWYRRRGGNNIRV--- 759
Query: 767 DPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAI 826
L + +V+++L+ PFTP++ EE+++ L + V + +P+V E+ I
Sbjct: 760 ----------LEEFLEVIIKLMMPFTPHLCEEMWEILGKE----GFVSLAKFPEVKEEFI 805
Query: 827 DEELEREMEFIRRIVEAGSAARQRAKIK-----------LRYPVRRIIIETEDETVKKAV 875
++E+E+ E+++ ++E AK++ +Y + +II E E +T+K+ +
Sbjct: 806 NDEIEKGEEYLKAVMEDIKEIINVAKVQPKRIYLYTADDWKYEILKIIKENEGKTIKELM 865
Query: 876 ERLNRILRDQLNAKEVKVGRVERELTIKPNFAKLGPEFKGDAKIIAKWINENGRELYEKG 935
+ + + KE+ + KL E + +++ EN +E +K
Sbjct: 866 PIIMKNPEFRKYGKEIP--------KLVNQLIKLNAEIINEVEVL-----ENAKEFLKK- 911
Query: 936 ELTVE 940
E+ VE
Sbjct: 912 EVGVE 916
>sp|O67411|SYV_AQUAE VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|7437657|pir||A70423 valine--tRNA ligase (EC 6.1.1.9)
- Aquifex aeolicus >gi|2983819|gb|AAC07375.1| (AE000739)
valyl-tRNA synthetase [Aquifex aeolicus]
Length = 1165
Score = 191 bits (481), Expect = 3e-47
Identities = 130/447 (29%), Positives = 223/447 (49%), Gaps = 61/447 (13%)
Query: 6 EFREYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKII 65
E +EY+P+++EEK ++W E +Y K ++ K+ + PP V+G++H+G A N +
Sbjct: 2 EIKEYNPREIEEKWSRYWIEKALYHVEKPDKRK--KFSVVIPPPNVTGSLHMGHALNATL 59
Query: 66 KDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEF 125
+D+I+R++ M+G PG+D G+ + VE+ L + K +E +G E F+KK E+
Sbjct: 60 QDVIVRWQRMRGRECVWVPGFDHAGIATQYVVEKQLAKEGKSRLE--LGREEFLKKVWEW 117
Query: 126 ALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCP 185
+ + Q LG+ +DW T+ + + + +E+GL+ + + +++WCP
Sbjct: 118 VPKSRNAIRTQLTKLGVSVDWKRERFTLDEGFSRAVRKAFRTLFEEGLIYRAEYIVNWCP 177
Query: 186 RCETALAEHEVRGEYKLRKDPSIYVKFPV---EGKE-NEYLLIWTTTPWTLPANLAVSAH 241
TAL++ EV EY+ K Y+K+P+ GK+ E++ + TT P T+ + AV+ +
Sbjct: 178 NDRTALSDLEV--EYEEEKGSLWYIKYPIVDENGKDTGEFITVATTRPETMLGDTAVAVN 235
Query: 242 PDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDE 301
P+ D R ++ + +A + V E ++ +G + L + I+ DE
Sbjct: 236 PNDD----------RYKHLVGKRARLPLVNWE-------RKDLRGNSVSNL--IPIIADE 276
Query: 302 YPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQ 361
V ++ GTG V P H DFE+G+ + LP +D+
Sbjct: 277 R---------------------VKMDFGTGAVKITPAHDPLDFEIGKTHDLPFVRVIDET 315
Query: 362 GKYTE--GKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQW 419
G+ E G + G+ EA I+ LRE L K EI H HC+RCKT + + QW
Sbjct: 316 GRMNENAGDFAGMDRYEAREAIVAKLREDELLEKEEEITHSVGHCYRCKTVIEPMVSVQW 375
Query: 420 FLKIS---------KVKDKIIKENDEK 437
F+K+S KV ++ IKE +EK
Sbjct: 376 FVKVSDPRIKDISIKVVEEGIKEREEK 402
Score = 176 bits (441), Expect = 1e-42
Identities = 105/359 (29%), Positives = 184/359 (51%), Gaps = 21/359 (5%)
Query: 537 KVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQ 596
K +++ + +DV+D WF S + + G+P + E + L+P D +V G D + W
Sbjct: 712 KCGSENLEQERDVLDTWFSSALWPFGVFGWPESTEDLKNLYPTDLLVTGFDIIFFWVARM 771
Query: 597 QAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWAT 656
+P+ V +H V D+ G KMSK++GN+I P +++ER G D RF + T
Sbjct: 772 IMMGTHFMKDIPFYDVYVHALVRDKYGRKMSKTIGNVIDPLDIIERYGADALRFTLAILT 831
Query: 657 NPWENLKFSWKGVEQVRRMLNILWNV--YVLASTYMSLDNFDPRKLNPDELPFREEDKWI 714
++K + + E + N +WN YVL +T ++F R P P + EDKWI
Sbjct: 832 VQGRDIKLAEEKFEGYKHFANKIWNAARYVLMNT---PEDFIAR--IPYMAPLKPEDKWI 886
Query: 715 LSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDP------ 768
++++N EV +E++ ++A A+Y F D WY+ ++R++ + +
Sbjct: 887 ITKLNETAEEVNKALENYQYSQAAHAIYEFFWSDYCDWYIEFTKERIYKKAPEDNEEEKA 946
Query: 769 ----DKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEK 824
++ A YTL V + LR+L PF PYI EE++ L P ES+ + ++P+ +E
Sbjct: 947 KVENERTTALYTLHYVLEKALRILHPFMPYITEELWHKL--PNAEGESISLAEFPQKNED 1004
Query: 825 AIDEELEREMEFIRRIVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERL-NRIL 882
I EE ++++E ++ I+ A A R +IK + + +TE E ++ ++ N IL
Sbjct: 1005 EIYEEDKQKVERLKEIISAIRAIRSDLQIKPSEKI-KASFKTESEFSRRVIQEFKNHIL 1062
>gb|AAF50346.1| (AE003553) CG5660 gene product [Drosophila melanogaster]
Length = 994
Score = 191 bits (480), Expect = 4e-47
Identities = 192/869 (22%), Positives = 344/869 (39%), Gaps = 140/869 (16%)
Query: 42 YYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQAL 101
Y L PP V+G +HLG A ++D+I R R GY V PG D G+ +V VE+ +
Sbjct: 75 YRMLLPPPNVTGNLHLGHALMATVQDVIARQREQLGYQVDWVPGTDHAGIATQVVVERTI 134
Query: 102 GLKTKKEIEEKIGVENFIKKCKEFALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESA 161
K E +G F+ + + + + + LG ++W Y T+ + +
Sbjct: 135 AASQAKTRHE-LGRSAFLDEVWRWKAEKGAGIVQDLRQLGCKLNWQREYFTMDEQQAHAV 193
Query: 162 WFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEY 221
+R +E+GL+++ V++WC +A+++ EV S+ + PVE Y
Sbjct: 194 NVAFERLFEEGLIQRRNSVVNWCTALRSAISDIEV---------DSVEITEPVEISVPGY 244
Query: 222 LLIWTTTPWTLPANLAVSAHPDYDYVKVKVEF--NGREEYWILAKALVDKVLGEIGVKGE 279
+ D+ Y V E +G E +++ + +LG++ V
Sbjct: 245 -----------DHKVLFGRMYDFAYHVVDGEALPDGSVEEIVVSTTRPETILGDVAVAVH 293
Query: 280 VVEE--FKGRELEGLRYVHILMDEYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAP 337
++ K R ++ ++ H D+ ++ V E GTG V P
Sbjct: 294 PLDPRYAKYRNIDQVKLKHPFRDD-------------TIPLVFDITVDQEFGTGAVKITP 340
Query: 338 GHGEEDFEVGQKYGLPVYSPLDDQGKYTE--GKWKGIYVKEADPKIIEHLREKGYLVKAG 395
H + DFE+ ++ L + G + ++KGI EA I+ L E L +
Sbjct: 341 AHDKFDFELATRHKLEPRQVFTETGLVVDAYSEYKGIPRFEARDLIVNRLEEMDLLRQVR 400
Query: 396 EIEHKYPHCWRCKTPLIFRATDQWFLKISKV-KDKIIKENDEKVTWYPDWVKIRFDNGVR 454
+ P C R K + + QWFLK + KD + + + ++ P + ++ ++
Sbjct: 401 SHTMQLPICSRSKDVIEYMILPQWFLKCKDLAKDALSELHSGRLQILPPNFETEWERWLQ 460
Query: 455 DSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKL 514
DS DW ISRQ +WG +P ++ D + + +
Sbjct: 461 DSRDWCISRQLWWGHQVPAYEVIDS----------------------------QGNSQWV 492
Query: 515 KVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFE 574
++EK + R +I ++R DV+D WF S + +++ G+P +E ++
Sbjct: 493 AALDEKTARQKAMR------LIGSEEFTLKRDPDVLDTWFSSSLLPFSTAGWP--EESYK 544
Query: 575 KLWPADFIVEGEDQVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNII 634
+ +P D + G D + W + P++R+ ++G V D G KMSKS+GNI+
Sbjct: 545 ERYPLDIMQTGHDIIFFWVARMMMLGLKLTGEAPFQRILLNGIVCDAHGRKMSKSIGNIV 604
Query: 635 RPEEVVERA-----------------------------------------GRDTFRFYML 653
P++VV+ A G D RF ++
Sbjct: 605 APQQVVQGASLESLKAGLEQSCEAGIITPSELKASTIGMTQMFPNGIQECGTDALRFTLM 664
Query: 654 WATNPWENLKFSWKGVEQVRRMLNILWNV--YVLASTY---MSLDNFDPRKLNPDELPFR 708
+ F + LN +W + L S +SL F+ + +
Sbjct: 665 SHNIKSHFISFDVNACHTNKLFLNKVWQAMRFTLGSAKGLGISLHQFE----TLEGVNLG 720
Query: 709 EEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDP 768
D+WI+ R+ +S ++ AT AL F + L Y+ + +
Sbjct: 721 LWDRWIVGRLAETLSVCSQSYSNYNFHLATAALKTFFYQYLCDTYLETTKPA--IGNRSA 778
Query: 769 DKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDE 828
D TL L+ +AP+ P++A E+ Q++ N+E + + D+ DE
Sbjct: 779 DAYIHVGTLTACLSWGLQAMAPYAPFVASELLQHVP---LNIE-LKLSDYK-------DE 827
Query: 829 ELEREMEFIRRIVEAGSAARQRAKIKLRY 857
+LE E+ I I + R +I R+
Sbjct: 828 KLEEEVNEIVNICHNVRQVKSRNEISKRH 856
>pir||S17675 valine--tRNA ligase (EC 6.1.1.9) - human >gi|31545|emb|CAA41990.1|
(X59303) valyl-tRNA synthetase [Homo sapiens]
Length = 1265
Score = 186 bits (468), Expect = 1e-45
Identities = 210/933 (22%), Positives = 361/933 (38%), Gaps = 203/933 (21%)
Query: 10 YDPKKLEEKVEKFWSENEIYRKV---KELRKDGPKYYFLD--GPPYVSGAIHLGTAWNKI 64
Y P+ +E +W + ++ + P+ F+ PP V+G++HLG A
Sbjct: 300 YSPRYVEAAWYPWWEQQGFFKPEYGRPNVSAANPRGVFMMCIPPPNVTGSLHLGHALTNA 359
Query: 65 IKDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKE 124
I+D + R+ M+G PG D G+ +V VE+ L + + ++G E F+++ +
Sbjct: 360 IQDSLTRWHRMRGETTLWNPGCDHAGIATQVVVEKKL-WREQGLSRHQLGREAFLQEVWK 418
Query: 125 FALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWC 184
+ + Q K LG +DWD T+ + + R E+G++ + R+++W
Sbjct: 419 WKEEKGDRIYHQLKKLGSSLDWDRACFTMDPKLSAAVTEAFVRLHEEGIIYRSTRLVNWS 478
Query: 185 PRCETALAEHEVRGE------------YKLRKDPSIYVKF--PVEGKE-NEYLLIWTTTP 229
+A+++ EV + YK + + + V F V+G + +E +++ TT
Sbjct: 479 CTLNSAISDIEVDKKELTGRTLLSVPGYKEKVEFGVLVSFAYKVQGSDSDEEVVVATTRI 538
Query: 230 WTLPANLAVSAHPD---YDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKG 286
T+ ++AV+ HP Y ++K K V+ F
Sbjct: 539 ETMLGDVAVAVHPKDTRYQHLKGK----------------------------NVIHPFLS 570
Query: 287 RELEGLRYVHILMDEYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEV 346
R L ++ +FV ++ GTG P H + D+EV
Sbjct: 571 RSLP---------------------------IVFDEFVDMDFGTGAGKITPAHDQNDYEV 603
Query: 347 GQKYGLPVYSPLDDQG--KYTEGKWKG-IYVKEADPKIIEHLREKGYLVKAGEIEHKYPH 403
GQ++GL S +D +G + G V + + L+E+G + P
Sbjct: 604 GQRHGLEAISIMDSRGGPHQCASAFPGPAQVLRPGKRCLVALKERGLFRGIEDNPMVVPL 663
Query: 404 CWRCKTPLIFRATDQWFLKISKVKD-----------KIIKENDEKVTWYPDWVKIRFDNG 452
C R K + QW+++ ++ +I+ E ++ TW+ IR
Sbjct: 664 CNRSKDVVEPLLRPQWYVRCGEMAQAASAAVTRGDLRILPEAHQR-TWHAWMDNIR---- 718
Query: 453 VRDSGDWVISRQRYWGIPLPIW------------QSEDGEIYVVGSWRELVELAVAIEVN 500
+W ISRQ +WG +P + + DG +V G
Sbjct: 719 -----EWCISRQLWWGHRIPAYFVTVSDPAVPPGEDPDGRYWVSGR-------------- 759
Query: 501 GERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIAS 560
E E ++ V +K+ +++ +DV+D WF SG+
Sbjct: 760 -NEAEAREKAAKEFGVSPDKI--------------------SLQQDEDVLDTWFFSGLFP 798
Query: 561 WASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLD 620
+ LG+P E +P + G D + W + +P+R V +H V D
Sbjct: 799 LSILGWPNQSEDLSVFYPGTLLETGHDILFFWVARMVMLGLKLTGRLPFREVYLHAIVRD 858
Query: 621 EKGDKMSKSLGNIIRPEEV----------------------VERA--------------- 643
G KMSKSLGN+I P +V VE+A
Sbjct: 859 AHGRKMSKSLGNVIDPLDVIYGISLQGLHNQLLNSNLDPSEVEKAKEGQKADFPAGIPEC 918
Query: 644 GRDTFRFYMLWATNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPD 703
G D RF + + ++ + R N LWN A + F P +P
Sbjct: 919 GTDALRFGLCAYMSQGRDINLDVNRILGYRHFCNKLWNATKFALRGLG-KGFVP---SPT 974
Query: 704 ELPFREE---DKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKR 760
P E D+WI SR+ + G +++ T A Y+F + +L Y+ ++
Sbjct: 975 SQPGGHESLVDRWIRSRLTEAVRLSNQGFQAYDFPAVTTAQYSFWLYELCDVYLECLKPV 1034
Query: 761 LWVEGEDPDKLA---AYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNV-ESVHML 816
L D++A A TL+ DV LRLL+PF P++ EE++Q L R S+ +
Sbjct: 1035 L----NGVDQVAAECARQTLYTCLDVGLRLLSPFMPFVTEELFQRLPRRMPQAPPSLCVT 1090
Query: 817 DWPKVDEKA-IDEELEREMEFIRRIVEAGSAAR 848
+P+ E + D E E +E I A + R
Sbjct: 1091 PYPEPSECSWKDPEAEAALELALSITRAVRSLR 1123
>pir||B82843 valyl-tRNA synthetase XF0134 [imported] - Xylella fastidiosa
(strain 9a5c) >gi|9104920|gb|AAF82947.1|AE003867_1
(AE003867) valyl-tRNA synthetase [Xylella fastidiosa]
Length = 994
Score = 186 bits (467), Expect = 1e-45
Identities = 213/978 (21%), Positives = 378/978 (37%), Gaps = 182/978 (18%)
Query: 10 YDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMI 69
YDP E ++ W ++ G Y L PP V+G +H+G A+ + + D +
Sbjct: 8 YDPTSFEARLYAAWEAAGHFKP----SGTGQPYTILLPPPNVTGTLHMGHAFQQTLMDAL 63
Query: 70 IRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNN 129
+R+ M G + Q G D G+ E+ V + + L+ E + +G + FI K E+ +
Sbjct: 64 VRYHRMCGDDTLWQVGTDHAGIATEMVVSRNVVLEGHGETRDSLGRDGFINKVWEWKQQS 123
Query: 130 LKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCET 189
+ Q + LG+ DW T+ + + R +E GL+ + +R+++W P +T
Sbjct: 124 GDTIERQMRRLGVSADWSRSTFTMDPQPSAAVTEAFVRWYEAGLIYRGQRLVNWDPVLKT 183
Query: 190 ALAEHEVRG----------EYKLRKDPSI-YVKFPVEGKE-----NEYLLIWTTTPWTLP 233
A+++ EV Y L + +V+ G E + L++ TT P TL
Sbjct: 184 AISDLEVENVAEEGMLWSIRYPLSDGVTYEHVEHDAAGNEILRETRDSLIVATTRPETLL 243
Query: 234 ANLAVSAHP-DYDYV-----KVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGR 287
+ AV HP D Y V + GR ++ A VD G VK +F
Sbjct: 244 GDTAVMVHPEDRRYTALIGKTVTLPLTGR-HIPVIGDAYVDPTFGTGVVKVTPAHDFNDY 302
Query: 288 ELEGLRY----VHILMDEYPRQKEFKEKYEWAHRVILADFVTLEEG-----TGLVHTAPG 338
++ GLR+ + +L D + +++ G T P
Sbjct: 303 QI-GLRHRLPMIQVLDD----------------AACIVSKTSIQSGMPSGATSDTTNTPS 345
Query: 339 HGEEDFEVGQKYGLPVYSPLDDQGKYTEGKWKGIYVKEADPKIIEHLREKGYLVKAGEIE 398
E Q L + + L +Y K +I+ L +G LV A
Sbjct: 346 DPEASSAANQHDTLVMPAHLAGLDRYAARK-----------QILADLDAQGLLVAAIPHT 394
Query: 399 HKYPHCWRCKTPLIFRATDQWFLKISKV--KDKIIKENDEKVTWYPDWVKIRFDNGVRDS 456
+ P R + T QWF+K+ + + + E P+W+ + + + +
Sbjct: 395 LQVPRGDRTGQVIEPYLTAQWFVKMETLAARGLALVERGAVTFVPPNWIN-TYRHWMENI 453
Query: 457 GDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKV 516
DW ISRQ +WG +P W G +YV S E+
Sbjct: 454 QDWCISRQLWWGHRIPAWFDTQGGVYVGRSEAEV-------------------------R 488
Query: 517 IEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFE-- 574
+ LGPE + + DV++ WF S + +++LG+P + E
Sbjct: 489 AKHALGPE----------------VTLTQDNDVLETWFSSQLWPFSTLGWPDPTAMAEHG 532
Query: 575 --KLWPADFIVEGEDQVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGN 632
+ P+ +V G D + W A+ VP+ V + G + D +G KMSKS GN
Sbjct: 533 YARYLPSSVLVTGFDIIFFWVARMIMATDHFTGNVPFHDVYITGLIRDAQGQKMSKSKGN 592
Query: 633 IIRPEEVVERA-------------------------------------GRDTFRFYMLWA 655
++ P ++++ G D RF +
Sbjct: 593 VLDPLDIIDGITLDDLVAKRTTGLMQPKLAEKIAKATRKEFPEGIAPHGADALRFTIAAL 652
Query: 656 TNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDE----------- 704
++KF E + N LWN A+ ++ ++ D +P +
Sbjct: 653 ATHGRDIKFDLGRAEGYKNFCNKLWN----ATRFVLMNTADDTAHSPAQHQAGQDGQDAP 708
Query: 705 ---LPFREEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRL 761
P + ++WILSR+ ++ +E ++ +ALY F + W+V L + L
Sbjct: 709 RTPQPRTDAEQWILSRLTAITAEAHAQFAAYRFDLLAQALYEFAWNEFCDWFVELAKPAL 768
Query: 762 WVEGEDPDKLAA--YYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHML--- 816
D + AA +TL V + LLRLL P P+I EE+++ + P +++ ++
Sbjct: 769 ---NSDDTQAAASTRHTLLYVLETLLRLLHPLIPFITEELWRQ-VAPRLGIQATTLMLRP 824
Query: 817 -DWPKVDEKAIDEELEREMEFIRRIVEAGSAARQRAKIKLRYPVRRI--IIETEDETVKK 873
P+ E A ++E+++ +V A R + P RR+ +++ + E ++
Sbjct: 825 YPQPQQLETAAFANAAADVEWLKIMVSALRRIRSTLNVP---PSRRVSLLLQGDQEVDRR 881
Query: 874 AVERLNRILRDQLNAKEV 891
+ L L + +
Sbjct: 882 RITHFATALHFLLKLEHI 899
>pir||PN0474 valine--tRNA ligase (EC 6.1.1.9) (version 2) - human (fragment)
Length = 1051
Score = 183 bits (461), Expect = 7e-45
Identities = 196/887 (22%), Positives = 341/887 (38%), Gaps = 201/887 (22%)
Query: 10 YDPKKLEEKVEKFWSENEIYRKVKELR--KDGPKYYFLD--GPPYVSGAIHLGTAWNKII 65
Y P+ +E +W + ++ L + P+ F+ PP V+G++HLG A I
Sbjct: 100 YSPRYVEAAWYPWWEQQGFFKPEYGLLMCQQNPRGVFMMCIPPPNVTGSLHLGHALTNAI 159
Query: 66 KDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEF 125
+D + R+ M+G PG D G+ +V VE+ L + + VE F+++ ++
Sbjct: 160 QDSLTRWHRMRGETTLWNPGCDHAGIATQVVVEKKLW--RDEGLSRHQLVEAFLQEVWKW 217
Query: 126 ALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCP 185
+ Q K LG +DWD T+ + + R E+G++ + R+++W
Sbjct: 218 KEEKGDRIYHQLKKLGSSLDWDRACFTMDPKLSAAVTEAFVRLHEEGIIYRSTRLVNWSC 277
Query: 186 RCETALAEHEVRGE------------YKLRKDPSIYVKF--PVEGKE-NEYLLIWTTTPW 230
+A+++ EV + YK + + + V F V+G + +E +++ TT
Sbjct: 278 TLNSAISDIEVDKKELTGRTLLSVPGYKEKVEFGVLVPFAYKVQGSDSDEEVVVATTRIE 337
Query: 231 TLPANLAVSAHPD---YDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGR 287
T+ ++AV+ HP Y ++K K V+ F R
Sbjct: 338 TMLGDVAVAVHPKDTRYQHLKGK----------------------------NVIHPFLSR 369
Query: 288 ELEGLRYVHILMDEYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVG 347
L ++ +FV ++ GTG V P H + D+EVG
Sbjct: 370 SLP---------------------------IVFDEFVDMDFGTGAVKITPAHDQNDYEVG 402
Query: 348 QKYGLPVYSPLDDQGKY--TEGKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCW 405
Q++GL S +D +G + G+ EA ++ L+E+G + P C
Sbjct: 403 QRHGLEAISIMDSRGALINVPPPFLGLPRFEARKAVLVALKERGLFRGIEDNPMVVPLCN 462
Query: 406 RCKTPLIFRATDQWFLKISKVKD-----------KIIKENDEKVTWYPDWVKIRFDNGVR 454
R K + QW+++ ++ +I+ E ++ TW+ IR
Sbjct: 463 RSKDVVEPLLRPQWYVRCGEMAQAASAAVTRGDLRILPEAHQR-TWHAWMDNIR------ 515
Query: 455 DSGDWVISRQRYWGIPLPIW------------QSEDGEIYVVGSWRELVELAVAIEVNGE 502
+W ISRQ +WG +P + + DG +V G
Sbjct: 516 ---EWCISRQLWWGHRIPAYFVTVSDPAVPPGEDPDGRYWVSGR---------------N 557
Query: 503 RIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWA 562
E E ++ V +K+ +++ +DV+D WF SG+ +
Sbjct: 558 EAEAREKAAKEFGVSPDKI--------------------SLQQDEDVLDTWFSSGLFPLS 597
Query: 563 SLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDEK 622
LG+P E +P + G D + W + +P+R V +H V D
Sbjct: 598 ILGWPNQSEDLSVFYPGTLLETGHDILFFWVARMVMLGLKLTGRLPFREVYLHAIVRDAH 657
Query: 623 GDKMSKSLGNIIRPEEV--------------------------------------VERAG 644
G KMSKSLGN+I P +V + G
Sbjct: 658 GRKMSKSLGNVIDPLDVIYGISLQRLLHNQLLNSNLDPSEVEKPKKRDRKLTPSGIPECG 717
Query: 645 RDTFRFYMLWATNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDE 704
D RF + + ++ + R N LWN A + F P +P
Sbjct: 718 TDALRFGLCAYMSQGRDINLDVNRILGYRHFCNKLWNATKFALRGLG-KGFLP---SPTS 773
Query: 705 LPFREE---DKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRL 761
P E D+WI SR+ + G +++ T + Y+ + +L Y+ ++ L
Sbjct: 774 QPGGHESLVDRWIRSRLTEAVRLSNQGFQAYDFPAVTTSQYSLWLYELCDVYLECLKPVL 833
Query: 762 WVEGEDPDKLA---AYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIR 805
D++A A TL+ DV +RLL+ F P++ EE++Q L R
Sbjct: 834 ----NGVDQVAAECARQTLYTCLDVAVRLLSTFIPFVTEELFQRLPR 876
>pir||T51503 valine--tRNA ligase-like protein - Arabidopsis thaliana
>gi|9755723|emb|CAC01835.1| (AL391147) valine--tRNA
ligase-like protein [Arabidopsis thaliana]
Length = 1093
Score = 182 bits (457), Expect = 2e-44
Identities = 224/1035 (21%), Positives = 401/1035 (38%), Gaps = 247/1035 (23%)
Query: 16 EEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRTM 75
EEK+ K+W ++ + G + PP V+G++H+G A ++D+++R+ M
Sbjct: 287 EEKIYKWWESQGYFKP--NFDQGGSPFVIPMPPPNVTGSLHMGHAMFVTLEDIMVRYNRM 344
Query: 76 QGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIMTE 135
G PG D G+ ++ VE+ L + K ++ +G + F K+ E+ +T
Sbjct: 345 NGRPTLWLPGTDHAGIATQLVVEKMLASEGIKRVD--LGRDEFTKRVWEWKEKYGGTITN 402
Query: 136 QFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHE 195
Q K LG DW T+ + + + +KGL+ + +++W P +TA+++ E
Sbjct: 403 QIKRLGASCDWSRERFTLDEQLSRAVVEAFVKLHDKGLIYQGSYMVNWSPNLQTAVSDLE 462
Query: 196 VRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVKVKVEFNG 255
V EY ++K+ V G ++L I TT P TL ++A++ HP+ D
Sbjct: 463 V--EYSEEPGFLYHIKYRVAGSP-DFLTIATTRPETLFGDVALAVHPEDD---------- 509
Query: 256 REEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFKEKYEWA 315
R ++ A+V G R+V I+ D+Y
Sbjct: 510 RYSKYVGQTAIVPMTYG--------------------RHVPIIADKY------------- 536
Query: 316 HRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTEGKWKGIYVK 375
V + GTG++ +PGH D+ + +K GLP+ + ++ T G++
Sbjct: 537 --------VDKDFGTGVLKISPGHDHNDYLLARKLGLPILNVMNKDA--TLNDVAGLFWF 586
Query: 376 EADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKDK-IIKEN 434
E K+ L E G VK + P R + + QWF+ + + +K ++
Sbjct: 587 EVREKLWADLEEIGLAVKKEPHTLRVPRSQRGGEVIEPLVSKQWFVHMDPLAEKALLAVE 646
Query: 435 DEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVELA 494
++++T P+ RF+ + D+++++
Sbjct: 647 NKELTIIPE----RFEKDCEE--DYIVAK------------------------------- 669
Query: 495 VAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWF 554
S EE L+ EK G + ++ + DV+D WF
Sbjct: 670 --------------SAEEALEKALEKYGKD----------------VEIYQDPDVLDTWF 699
Query: 555 DSGIASWASLGYPR-NKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVAFDTVPYRRVA 613
S + +++LG+P + F +P + + G I TVP+ V
Sbjct: 700 SSSLWPFSTLGWPDVAAKDFNNFYPTNMLETG----------MVMMGIEFTGTVPFSHVY 749
Query: 614 MHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENLKFSWKGVEQVR 673
+HG + D +G KMSKSLGN+I P + ++ G D RF + T ++L S + + +
Sbjct: 750 LHGLIRDSQGRKMSKSLGNVIDPLDTIKDFGTDALRFTIALGT-AGQDLNLSTERLTANK 808
Query: 674 RMLNILWNV--YVL-----ASTYMSLDNFDPRKLNPDE--LPFREEDKWILSRVNSLISE 724
N LWN +VL S + +N KL+ +E L + W +S+++ LI
Sbjct: 809 AFTNKLWNAGKFVLHSLPSLSDTSAWENLLDLKLDKEETLLSLPLPECWAVSKLHILIDS 868
Query: 725 VENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFDVL 784
V E + A L VF+ +
Sbjct: 869 VTASYEKLFFGDA--------------------------------------VLLYVFENI 890
Query: 785 LRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREMEFIRRIVEAG 844
L+LL PF P++ E+++Q L P+ E++ + WP+ L R +E I+R
Sbjct: 891 LKLLHPFMPFVTEDLWQAL--PYRK-EALIVSPWPQ-------NSLPRNVESIKRFENLQ 940
Query: 845 SAARQRAKIKLRY---PVRRIIIETEDETVKKAVERLNRILRDQLNAKEVKVGRVERELT 901
+ R + Y PV+RI + +K E L + R LN
Sbjct: 941 ALTRAIRNARAEYSVEPVKRISASVVG-SAEKEKEVLALLSRLDLN-------------- 985
Query: 902 IKPNFAKLGPEFKGDAKIIAKWINENGRELYEKGELTVEIDGKTFHLTREHIIVEEKLPD 961
+F+ P GDA + + G E Y V+I + +++ ++ + D
Sbjct: 986 -NVHFSNAPP---GDANLSVHLVASEGLEAYLPLAAMVDISSEVQRISKRLSKMQTEY-D 1040
Query: 962 FFVSEEFEGGRVFVDKTLTRELIAEGLAREFVRRIQEMRKRLDLDVNDRIIVTIETTDEN 1021
++ L+ E E VR ++E +E +E
Sbjct: 1041 ALITR------------LSSPKFVEKAPEEVVRGVKEQ---------------VEELEEK 1073
Query: 1022 VELLKENLDYIMRET 1036
++L K LD++ T
Sbjct: 1074 IKLTKARLDFLKSTT 1088
>dbj|BAB14164.1| (AK022665) unnamed protein product [Homo sapiens]
Length = 567
Score = 179 bits (450), Expect = 1e-43
Identities = 128/432 (29%), Positives = 214/432 (48%), Gaps = 54/432 (12%)
Query: 391 LVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKDKIIKENDEKVTWYPDWVKIRFD 450
L+K ++ H YP+ WR K P++ RA+ QWF+ I+ +K KE +KV + P
Sbjct: 8 LLKEEKLVHSYPYDWRTKKPVVIRASKQWFINITDIKTAA-KELLKKVKFIPGSAL---- 62
Query: 451 NGVRDSGD----WVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVELAVAIEVNGERI-- 504
NG+ + D W ISRQR WG+P+P++ + + Y++ S + + +E +G I
Sbjct: 63 NGMVEMMDRRPYWCISRQRVWGVPIPVFHHKTKDEYLINS-QTTEHIVKLVEQHGSDIWW 121
Query: 505 ELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASL 564
LP +V+ E GP+ L YV +D++D+WFDSG + L
Sbjct: 122 TLPPEQLLPKEVLSEVGGPDALE--YVPG-------------QDILDIWFDSGTSWSYVL 166
Query: 565 GYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGD 624
P + AD +EG+DQ+ WF S S+ A Y+ V +HG+ L EKG+
Sbjct: 167 PGPDQR--------ADLYLEGKDQLGGWFQSSLLTSVAARKRALYKTVIVHGFTLGEKGE 218
Query: 625 KMSKSLGNIIRPEEVVERA---------GRDTFRFYMLWATNPWENLKFSWKGVEQVRRM 675
KMSKSLGN+I P+ VV G D R+++ +N + + + R
Sbjct: 219 KMSKSLGNVIHPDVVVNGGQDQSKEPPYGADVLRWWVA-DSNVFTEVAIGPSVLNAARDD 277
Query: 676 LNILWNVYVLASTYMSLDNFDPRKLNPDELPFREE---DKWILSRVNSLISEVENGIESF 732
++ L N L ++ +F+P D +P + D+++L + L +++ + +
Sbjct: 278 ISKLRN--TLRFLLGNVADFNP---ETDSIPVNDMYVIDQYMLHLLQDLANKITELYKQY 332
Query: 733 YLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGE-DPDKLAAYYTLWKVFDVLLRLLAPF 791
K R L F +LS +Y +I+ RL+ E E DP + + L ++ DV++R AP
Sbjct: 333 DFGKVVRLLRTFYTRELSNFYFSIIKDRLYCEKENDPKRRSCQTALVEILDVIVRSFAPI 392
Query: 792 TPYIAEEIYQNL 803
P++AEE++Q++
Sbjct: 393 LPHLAEEVFQHI 404
>sp|P36430|SYL_BACSU LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS)
>gi|7437539|pir||D69650 leucine--tRNA ligase (EC
6.1.1.4) - Bacillus subtilis >gi|2293181|gb|AAC00259.1|
(AF008220) leucine tRNA synthetase [Bacillus subtilis]
>gi|2635516|emb|CAB15010.1| (Z99119) leucyl-tRNA
synthetase [Bacillus subtilis]
Length = 804
Score = 174 bits (436), Expect = 6e-42
Identities = 220/943 (23%), Positives = 365/943 (38%), Gaps = 230/943 (24%)
Query: 10 YDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGA-IHLGTAWNKIIKDM 68
+ K++E+K + +W EN+ + + K K+Y LD PY SGA +H+G D+
Sbjct: 3 FQHKEIEKKWQTYWLENKTFATLDNNEKQ--KFYALDMFPYPSGAGLHVGHPEGYTATDI 60
Query: 69 IIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALN 128
+ R + MQGY+V G+D GLP E + AL + K ++NF +
Sbjct: 61 LSRMKRMQGYDVLHPMGWDAFGLPAE---QYALDTGNDPAVFTKQNIDNFRR-------- 109
Query: 129 NLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCE 188
Q + LG DWD T EY + + + +EKGL D+ ++WCP
Sbjct: 110 -------QIQALGFSYDWDREINTTDPEYYKWTQWIFLKLYEKGLAYVDEVPVNWCPALG 162
Query: 189 TALAEHEV------RGEYKLRKDP------------------------------------ 206
T LA EV RG + + + P
Sbjct: 163 TVLANEEVIDGKSERGGHPVERRPMKQWMLKITAYADRLLEDLEELDWPESIKDMQRNWI 222
Query: 207 ----SIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVKVKVEFNGREEYWIL 262
+V F ++G ++ + ++TT P TL P++ V+ E+
Sbjct: 223 GRSEGAHVHFAIDGHDDSF-TVFTTRPDTLFGATYTVLAPEHALVE---NITTAEQ---- 274
Query: 263 AKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFKEKYEWAHRVILAD 322
K V+ + EI K ++ + G + Y EK + +AD
Sbjct: 275 -KEAVEAYIKEIQSKSDLERTDLAKTKTG-----VFTGAYAINPVNGEKLP----IWIAD 324
Query: 323 FVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLD----DQGKYT-EGK------WKG 371
+V GTG V PGH E DFE + +GLPV + ++ YT +G+ G
Sbjct: 325 YVLASYGTGAVMAVPGHDERDFEFAKTFGLPVKEVVKGGNVEEAAYTGDGEHVNSDFLNG 384
Query: 372 IYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKDKII 431
++ +EA K+I L E
Sbjct: 385 LHKQEAIEKVIAWLEE-------------------------------------------T 401
Query: 432 KENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELV 491
K ++KVT+ ++R DW+ SRQRYWG P+P+ EDG V
Sbjct: 402 KNGEKKVTY-----RLR---------DWLFSRQRYWGEPIPVIHWEDGTSTAVPE----E 443
Query: 492 ELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVD 551
EL + + E I+ + E L I+E + D GK RR + +
Sbjct: 444 ELPLILPKTDE-IKPSGTGESPLANIKEWVEVTD-----------PETGKKGRRETNTMP 491
Query: 552 VWFDSGIASWASLGY--PRN------KELFEKLWPADFIVEGEDQVT-----KWFYSQQA 598
W S W L Y P N E EK P D + G + F+ +
Sbjct: 492 QWAGS---CWYFLRYIDPHNPDQLASPEKLEKWLPVDMYIGGAEHAVLHLLYARFWHKFL 548
Query: 599 ASIVAFDT-VPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATN 657
I T P++++ G +L E +KMSKS GN++ P+E+V G DT R Y ++
Sbjct: 549 YDIGVVPTKEPFQKLYNQGMILGENNEKMSKSKGNVVNPDEIVASHGADTLRLYEMFMGP 608
Query: 658 PWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSR 717
++ +S G++ RR L+ +W +++ D +LN + E L R
Sbjct: 609 LDASIAWSESGLDGARRFLDRVWRLFI----------EDSGELNGKIVEGAGE---TLER 655
Query: 718 V-NSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYT 776
V + + +V + E L F+ E Y + ++EG
Sbjct: 656 VYHETVMKVTDHYEGLRFNTGISQLMVFINEA----YKATELPKEYMEG----------- 700
Query: 777 LWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDE-KAIDEELEREME 835
++LL+P P++AEE+++ L T + WP DE K +D+E+E ++
Sbjct: 701 -------FVKLLSPVAPHLAEELWEKLGHSGT----IAYEAWPVYDETKLVDDEVEIVVQ 749
Query: 836 F---IRRIVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAV 875
++ ++ + A + +L ++ + E +T++K +
Sbjct: 750 LNGKVKAKLQVPADATKEQLEQLAQADEKVKEQLEGKTIRKII 792
>sp|Q94425|SYI_CIOIN PROBABLE ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE)
(ILERS) >gi|7512111|pir||T31663 isoleucine--tRNA ligase
(EC 6.1.1.5) - sea squirt (Ciona intestinalis)
(fragment) >gi|1638826|emb|CAB02584.1| (Z80904) COS1.1
[Ciona intestinalis]
Length = 413
Score = 171 bits (430), Expect = 3e-41
Identities = 124/435 (28%), Positives = 206/435 (46%), Gaps = 75/435 (17%)
Query: 317 RVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYT-------EGKW 369
R+I +D +GTG+VH AP HG +DF +GQK+ L S ++ G++ EGK+
Sbjct: 15 RMIGSDIANTSKGTGVVHIAPAHGMDDFGIGQKHNLSTESSVNSDGEFMANIAPNLEGKF 74
Query: 370 KGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKDK 429
EA ++E L+E+ L + +H YP+ WR K P+ ++QWF+ + + +K
Sbjct: 75 IFTSGNEA---VVEMLKEEMNLFHEHDYKHSYPYDWRTKQPIFVHTSNQWFVDTAMLANK 131
Query: 430 IIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPI-WQSEDGEIYVVGSWR 488
+ +T YPD N ++ W ISRQR WG+P+P+ + E GE+
Sbjct: 132 A-EAAISGITTYPDNGISSMLNRLQLRSYWCISRQRAWGLPIPVFYHKESGELL------ 184
Query: 489 ELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKD 548
L ES + L + K G D+ + + N + R +D
Sbjct: 185 -----------------LNESTIQHLVSLVLKHGA-DIWWEGTELLPTQYNADEYERGRD 226
Query: 549 VVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVAFDTVP 608
++D+WFDSG++ L +N+ ADF +EG+DQ WF S S+ P
Sbjct: 227 ILDIWFDSGVSWDCVLRDSKNRTT-----QADFYIEGKDQYGGWFQSSLLTSVGLQGVAP 281
Query: 609 YRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERA---------GRDTFRFYMLWATNPW 659
Y+ + +HG+VLDEKG KMSKS+GN++ P + G D R+++ +N
Sbjct: 282 YKNLMVHGFVLDEKGQKMSKSIGNVVDPMVLTNGGKNPQRDPAYGADALRWWVA-ESNVH 340
Query: 660 EN-------LKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPD------ELP 706
++ +K + + V+++R + + +L+ FD K+ P +L
Sbjct: 341 QDVHISTTIIKSAAESVQKIRNSVRFMLG---------NLNEFDKMKIVPTPAMLILDLR 391
Query: 707 FREEDK--WILSRVN 719
+R EDK W ++ +N
Sbjct: 392 YRFEDKKLWYVTSMN 406
>pir||D75307 leucyl-tRNA synthetase - Deinococcus radiodurans (strain R1)
>gi|6459971|gb|AAF11720.1|AE002050_6 (AE002050)
leucyl-tRNA synthetase [Deinococcus radiodurans]
Length = 874
Score = 171 bits (429), Expect = 4e-41
Identities = 217/954 (22%), Positives = 373/954 (38%), Gaps = 205/954 (21%)
Query: 2 IKEPEFREYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAW 61
I+EP Y+P +E+K + W E+ +Y+ + G K+Y L PY SG +H+G +
Sbjct: 61 IQEPRAERYNPHAIEQKWQGQWQESGLYKF--DENAPGEKFYALTMFPYPSGNLHIGHWY 118
Query: 62 NKIIKDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKK 121
+ D R+ M+GYNV +D GLP E ++N
Sbjct: 119 ANVAPDARARWLRMRGYNVLFPMAFDAFGLPAE-----------------NAAIKNNTNP 161
Query: 122 CKEFALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIE-SAWFTLKRAWEKGLLEKDKRV 180
+ N++ MT QF +G +DW + T EY + WF ++ W++GL K +
Sbjct: 162 AT-WTYANIERMTGQFSRMGTMIDWSRKFATCDPEYYRWNQWFFIE-FWKRGLAYKKGGL 219
Query: 181 LHWCPRCETALAEHEVRGEYKLRKDPSI--------YVKF-----------------PVE 215
++WCP+ +T LA +V + R ++ Y+K V
Sbjct: 220 VNWCPKDQTVLANEQVVNGHCERCGTAVERRNLSQWYLKITDYAEELLDFSATDMPEKVR 279
Query: 216 GKENEYL-----------------LIWTTTPWTLPANLAVSAHPDYDYVKVKVEFNGREE 258
+ ++ ++TT P TL + P++ VK E E+
Sbjct: 280 AMQTNWIGKSVGAEVTFDTPAGPETVFTTRPDTLMGATFMVLAPEHAKVK---ELTTDEQ 336
Query: 259 YWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFKEKYE-WAHR 317
+A V+ + G K +V + +G + + Y + W
Sbjct: 337 -----RAEVEAYVAAAGRKTDVERQQEGEK------TGVFTGSYATHPISGHQLPIWVAD 385
Query: 318 VILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTEGKWKGIYVKEA 377
+L + GTG + P H E DF +K+ LP+ + +G +G+ + +
Sbjct: 386 YVLVTY-----GTGSIMAVPAHDERDFAFAKKFDLPIREVIRAEGS------EGMGDQPS 434
Query: 378 DPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKDKIIKENDEK 437
+P +G +V +GE + P +I R ++ K K
Sbjct: 435 EP-----YSGEGQIVNSGEFD-GMPGGKASIAAIIARLEERGVAK-------------AK 475
Query: 438 VTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVELAVAI 497
T+ ++R DW+ +RQRYWG P+P E + V + V+L
Sbjct: 476 TTY-----RLR---------DWLFARQRYWGTPIPFVHCEKCGMQPVPEDQLPVKLP--- 518
Query: 498 EVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSG 557
E + + + LK+ EE G R D +D + DS
Sbjct: 519 ----ENVAFTPTGQSPLKLDEE-----------WKTTTCPCCGGPAERETDTMDTFVDSS 563
Query: 558 IASWASLGYPRNKELFEK----LWPADFIVEG-EDQVTKWFYSQQAASI-----VAFDTV 607
+ L + F+ L P D G E + YS+ + + +
Sbjct: 564 WYMYRYLSPNYDGGPFDPSKAGLLPVDLYTGGIEHAILHLLYSRFWTKVMRDMGLTTQSE 623
Query: 608 PYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENLKFSW- 666
P+ R+ G VL E G+KMSKS GN++ P+++V G DT R ++++ PWE L W
Sbjct: 624 PFARLRNQGMVLGEDGEKMSKSRGNVVDPDDLVREYGADTVRAFLMFIA-PWE-LGGPWD 681
Query: 667 -KGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISEV 725
+G+ + L+ +WNV+ F+ + P+E + + + V+S + +V
Sbjct: 682 PQGINGPSKWLSRVWNVF-----------FEEKVSGPEE---KMQGADVRFAVHSALKKV 727
Query: 726 ENGIESFYLTKATRALYNFVVEDLSRWYVRLIR-KRLWVEGEDPDKLAAYYTLW-KVFDV 783
+ E R +N ++ L L++ KR V G +W + D+
Sbjct: 728 NDDFE--------RMSFNTIISTLMELTNALVKAKRSPVFGT---------PVWEEALDI 770
Query: 784 LLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREMEFIRRIVEA 843
R+LAP P+IAEEI+ SVH WP+VDE A +R V
Sbjct: 771 FNRMLAPVVPHIAEEIWHER----GQKGSVHTAQWPQVDEAAA----------VRDTVTI 816
Query: 844 GSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQLNAKEVKV-GRV 896
G + K++ + + + E + +A+ + + L + KE+ V GR+
Sbjct: 817 G--VQVSGKVRGEVSISKTASQEEALSAARAIAEVQKHLEGKTVVKEIYVPGRI 868
>sp|P07813|SYL_ECOLI LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS)
>gi|7428464|pir||SYECL leucine--tRNA ligase (EC 6.1.1.4)
[validated] - Escherichia coli
>gi|1651269|dbj|BAA35289.1| (D90704) Leucine-tRNA ligase
(EC 6.1.1.4). [Escherichia coli]
>gi|1786861|gb|AAC73743.1| (AE000168) leucine tRNA
synthetase [Escherichia coli K12]
Length = 860
Score = 168 bits (422), Expect = 2e-40
Identities = 232/932 (24%), Positives = 348/932 (36%), Gaps = 248/932 (26%)
Query: 9 EYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDM 68
+Y P+++E KV+ W E + ++ K+ KYY L PY SG +H+G N I D+
Sbjct: 4 QYRPEEIESKVQLHWDEKRTFEVTEDESKE--KYYCLSMLPYPSGRLHMGHVRNYTIGDV 61
Query: 69 IIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALN 128
I R++ M G NV + G+D GLP E G K + +
Sbjct: 62 IARYQRMLGKNVLQPIGWDAFGLPAE-------GAAVKNNTAP-----------APWTYD 103
Query: 129 NLKIMTEQFKMLGIWMDWDNPYMTIKNEYI--ESAWFTLKRAWEKGLLEKDKRVLHWCPR 186
N+ M Q KMLG DW T EY E +FT ++KGL+ K ++WCP
Sbjct: 104 NIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFT--ELYKKGLVYKKTSAVNWCPN 161
Query: 187 CETALAEHEV------RGEYKLRKD--PSIYVKFPV------------------------ 214
+T LA +V R + K+ + P ++K
Sbjct: 162 DQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQR 221
Query: 215 ------EGKE-----NEY---LLIWTTTPWTLP--ANLAVSA-HPDYDYVKVKVEFNGRE 257
EG E N+Y L ++TT P T LAV+A HP + K N E
Sbjct: 222 NWIGRSEGVEITFNVNDYDNTLTVYTTRPDTFMGCTYLAVAAGHP----LAQKAAENNPE 277
Query: 258 EYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFKEKYEWAHR 317
A +D+ + E+ K G + VH L E E WA
Sbjct: 278 -----LAAFIDECRNTKVAEAEMATMEKKGVDTGFKAVHPLTGE--------EIPVWA-- 322
Query: 318 VILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTEGKWKGIYVKEA 377
A+FV +E GTG V PGH + D+E KYGL + + + +
Sbjct: 323 ---ANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPVI-------------LAADGS 366
Query: 378 DPKIIEH-LREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKDKI--IKEN 434
+P + + L EKG L +GE F D + + DK+ +
Sbjct: 367 EPDLSQQALTEKGVLFNSGE----------------FNGLDH-EAAFNAIADKLTAMGVG 409
Query: 435 DEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVELA 494
+ KV + ++R DW +SRQRYWG P+P+ EDG + + V L
Sbjct: 410 ERKVNY-----RLR---------DWGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILP 455
Query: 495 VAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWF 554
+ ++G + K PE VNG R D D +
Sbjct: 456 EDVVMDGITSPI-------------KADPEWAK--------TTVNGMPALRETDTFDTFM 494
Query: 555 DSGIASWASLGY--PRNKELF-----EKLW-PADFIVEGEDQVT------KWFYSQQAAS 600
+S SW Y P+ KE W P D + G + ++F+ +
Sbjct: 495 ES---SWYYARYTCPQYKEGMLDSEAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDA 551
Query: 601 IVAFDTVPYRRVAMHGYVL-------------------------DEKG------------ 623
+ P +++ G VL DEKG
Sbjct: 552 GMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHE 611
Query: 624 ------DKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENLKFSWKGVEQVRRMLN 677
KMSKS N I P+ +VER G DT R +M++A+ L++ GVE R L
Sbjct: 612 LVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLK 671
Query: 678 ILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISEVENGIESFYLTKA 737
+W + Y D LN D L E K + V+ I++V + I
Sbjct: 672 RVWKL-----VYEHTAKGDVAALNVDAL--TENQKALRRDVHKTIAKVTDDI-------G 717
Query: 738 TRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFDVLLRLLAPFTPYIAE 797
R +N + + +L + +GE L + + ++R+L PFTP+I
Sbjct: 718 RRQTFNTAIAAIMELMNKLAKAP--TDGEQDRAL-----MQEALLAVVRMLNPFTPHICF 770
Query: 798 EIYQNLIRPFTNVESVHMLDWPKVDEKAIDEE 829
++Q L + WP DEKA+ E+
Sbjct: 771 TLWQEL----KGEGDIDNAPWPVADEKAMVED 798
>gb|AAB40843.1| (U82598) leucine tRNA synthetase [Escherichia coli]
Length = 907
Score = 168 bits (421), Expect = 3e-40
Identities = 225/929 (24%), Positives = 343/929 (36%), Gaps = 242/929 (26%)
Query: 9 EYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDM 68
+Y P+++E KV+ W E + ++ K+ KYY L PY SG +H+G N I D+
Sbjct: 51 QYRPEEIESKVQLHWDEKRTFEVTEDESKE--KYYCLSMLPYPSGRLHMGHVRNYTIGDV 108
Query: 69 IIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALN 128
I R++ M G NV + G+D GLP E G K + +
Sbjct: 109 IARYQRMLGKNVLQPIGWDAFGLPAE-------GAAVKNNTAP-----------APWTYD 150
Query: 129 NLKIMTEQFKMLGIWMDWDNPYMTIKNEYI--ESAWFTLKRAWEKGLLEKDKRVLHWCPR 186
N+ M Q KMLG DW T EY E +FT ++KGL+ K ++WCP
Sbjct: 151 NIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFT--ELYKKGLVYKKTSAVNWCPN 208
Query: 187 CETALAEHEV------RGEYKLRKD--PSIYVKFPV------------------------ 214
+T LA +V R + K+ + P ++K
Sbjct: 209 DQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQR 268
Query: 215 ------EGKE-----NEY---LLIWTTTPWTLPANLAVSAHPDYDYVKVKVEFNGREEYW 260
EG E N+Y L ++TT P T ++ + + E N
Sbjct: 269 NWIGRSEGVEITFNVNDYDNTLTVYTTRPDTFMGCTYLAVRAGHPLAQKAAENNPE---- 324
Query: 261 ILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFKEKYEWAHRVIL 320
A +D+ + E+ K G + VH L E E WA
Sbjct: 325 --LAAFIDECRNTKVAEAEMATMEKKGVDTGFKAVHPLTGE--------EIPVWA----- 369
Query: 321 ADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTEGKWKGIYVKEADPK 380
A+FV +E GTG V PGH + D+E KYGL + + + ++P
Sbjct: 370 ANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPVI-------------LAADGSEPD 416
Query: 381 IIEH-LREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKDKI--IKENDEK 437
+ + L EKG L +GE F D + + DK+ + + K
Sbjct: 417 LSQQALTEKGVLFNSGE----------------FNGLDH-EAAFNAIADKLTAMGVGERK 459
Query: 438 VTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVELAVAI 497
V + ++R DW +SRQRYWG P+P+ EDG + + V L +
Sbjct: 460 VNY-----RLR---------DWGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILPEDV 505
Query: 498 EVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSG 557
++G + K PE VNG R D D + +S
Sbjct: 506 VMDGITSPI-------------KADPEWAK--------TTVNGMPALRETDTFDTFMES- 543
Query: 558 IASWASLGY--PRNKELF-----EKLW-PADFIVEGEDQVT------KWFYSQQAASIVA 603
SW Y P+ KE W P D + G + ++F+ + +
Sbjct: 544 --SWYYARYTCPQYKEGMLDSEAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMV 601
Query: 604 FDTVPYRRVAMHGYVL-------------------------DEKG--------------- 623
P +++ G VL DEKG
Sbjct: 602 NSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVY 661
Query: 624 ---DKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENLKFSWKGVEQVRRMLNILW 680
KMSKS N I P+ +VER G DT R +M++A+ L++ GVE R L +W
Sbjct: 662 TGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRVW 721
Query: 681 NVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISEVENGIESFYLTKATRA 740
+ Y D LN D L E K + V+ I++V + I R
Sbjct: 722 KL-----VYEHTAKGDVAALNVDAL--TENQKALRRDVHKTIAKVTDDI-------GRRQ 767
Query: 741 LYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIY 800
+N + + +L + +GE L + + ++R+L PFTP+I ++
Sbjct: 768 TFNTAIAAIMELMNKLAKAP--TDGEQDRAL-----MQEALLAVVRMLNPFTPHICFTLW 820
Query: 801 QNLIRPFTNVESVHMLDWPKVDEKAIDEE 829
Q L + WP DEKA+ E+
Sbjct: 821 QEL----KGEGDIDNAPWPVADEKAMVED 845
>pir||G82260 leucyl-tRNA synthetase VC0956 [imported] - Vibrio cholerae (group
O1 strain N16961) >gi|9655415|gb|AAF94118.1| (AE004177)
leucyl-tRNA synthetase [Vibrio cholerae]
Length = 894
Score = 168 bits (420), Expect = 4e-40
Identities = 226/987 (22%), Positives = 372/987 (36%), Gaps = 267/987 (27%)
Query: 9 EYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDM 68
+Y+P+ +E KV++ W N+ + ++ K+ K+Y L PY SG +H+G N I D+
Sbjct: 40 QYNPQDIEHKVQQHWDNNKTFVVSEDPNKE--KFYCLSMFPYPSGRLHMGHVRNYTIGDV 97
Query: 69 IIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALN 128
+ RF+ +QG NV + G+D GLP E V+N +
Sbjct: 98 VSRFQRLQGKNVLQPIGWDAFGLP-----------------AENAAVKNNTAPA-PWTYE 139
Query: 129 NLKIMTEQFKMLGIWMDWDNPYMTIKNEYI--ESAWFTLKRAWEKGLLEKDKRVLHWCPR 186
N++ M Q K+LG DW+ + T + EY E +FT + + KGL+ K ++WCP
Sbjct: 140 NIEYMKNQLKLLGFGYDWNREFATCRPEYYRWEQEFFT--KLFAKGLVYKKTSSVNWCPN 197
Query: 187 CETALAEHEVRG----------EYK----------------------------------- 201
+T LA +V E K
Sbjct: 198 DQTVLANEQVEDGCCWRCDTPVEQKEIPQWFIKITAYAQELLDDLDNLDGWPEMVKTMQR 257
Query: 202 --LRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAV---SAHPDYDYVKVKVEFNGR 256
+ + + +KF V+G EN L ++TT P TL V + HP + K N
Sbjct: 258 NWIGRSEGVELKFAVKG-ENTDLEVYTTRPDTLMGVTYVGIAAGHP----LATKAAANNP 312
Query: 257 EEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMD-EYPRQKEFKEKYEWA 315
A +D+ + E+ K GL +H L E P
Sbjct: 313 -----ALAAFIDECKNTKVAEAEIATMEKKGMATGLTAIHPLNGREVP------------ 355
Query: 316 HRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGL---PVYSPLDDQGKYTEGKWKGI 372
+ +A+FV ++ GTG V P H + DFE KYGL PV P D +
Sbjct: 356 --IYIANFVLMDYGTGAVMAVPAHDQRDFEFATKYGLDIIPVIKPADG---------SEL 404
Query: 373 YVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKDKIIK 432
V EA EKG L +GE + L F+A + + K+
Sbjct: 405 DVSEA------AYTEKGVLFASGEFD-----------GLDFQAA------FNAIAAKLEA 441
Query: 433 ENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVE 492
E K T V R DW +SRQRYWG P+P+ +EDG+++
Sbjct: 442 EGKGKKT-----VNFRL-------RDWGVSRQRYWGAPIPMVTTEDGQVH---------- 479
Query: 493 LAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDV 552
+ + + LPE V++ P + + NG+ R D D
Sbjct: 480 ---PVPADQLPVILPEDV-----VMDGVTSPIKADKEWAKT---TFNGEPALRETDTFDT 528
Query: 553 WFDSGIASWASLGY--PRNKELFE----KLW-PADFIVEGEDQV------TKWFYSQQAA 599
+ +S SW Y P+ ++ + W P D + G + +++F+
Sbjct: 529 FMES---SWYYARYCSPQADDILDPEKANYWLPVDQYIGGIEHACMHLLYSRFFHKLLRD 585
Query: 600 SIVAFDTVPYRRVAMHGYVL-------DEKGDK--------------------------- 625
+ P++++ G VL ++KG K
Sbjct: 586 AGYVKSDEPFKKLLCQGMVLADAFYYTNDKGGKEWVSPTEVKVERDGKGRIVSAVDATGR 645
Query: 626 ---------MSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENLKFSWKGVEQVRRML 676
MSKS N I P+E+V++ G DT R +M++A+ L++ GVE R L
Sbjct: 646 QVEHSGMIKMSKSKNNGIDPQEMVDKYGADTVRLFMMFASPADMTLEWQESGVEGANRFL 705
Query: 677 NILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISEVENGIESFYLTK 736
+W + + D LN D+ R + V+ I++V + +
Sbjct: 706 RRVWKLVREHTELGQAPALDASALNADQKALRRD-------VHKTIAKVTDDV------- 751
Query: 737 ATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFDVLLRLLAPFTPYIA 796
A R +N + + +L + + E +D L + + +L P TP+I
Sbjct: 752 ARRQTFNTAIAAIMELMNKLTKAPM-TEAQD------RAILDEALKAITLMLYPITPHIC 804
Query: 797 EEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEE-----LEREMEFIRRIVEAGSAARQRA 851
E++ L ++ WP DE A+ E+ L+ + ++ A A +Q+
Sbjct: 805 FEMWVAL-----GQSNIDTASWPTYDEAALVEDEKLIVLQVNGKLRGKLTVAADATQQQV 859
Query: 852 KIKLRYPVRRIIIETEDETVKKAVERL 878
+ + +DE V+K ++ L
Sbjct: 860 E----------ALGMQDENVQKFIDGL 876
>emb|CAA29642.1| (X06331) leucyl-tRNA synthetase [Escherichia coli]
Length = 860
Score = 167 bits (419), Expect = 5e-40
Identities = 225/929 (24%), Positives = 343/929 (36%), Gaps = 242/929 (26%)
Query: 9 EYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDM 68
+Y P+++E KV+ W E + ++ K+ KYY L PY SG +H+G N I D+
Sbjct: 4 QYRPEEIESKVQLHWDEKRTFEVTEDESKE--KYYCLSMLPYPSGRLHMGHVRNYTIGDV 61
Query: 69 IIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALN 128
I R++ M G NV + G+D GLP E G K + +
Sbjct: 62 IARYQHMLGKNVLQPIGWDAFGLPAE-------GAAVKNNTAP-----------APWTYD 103
Query: 129 NLKIMTEQFKMLGIWMDWDNPYMTIKNEYI--ESAWFTLKRAWEKGLLEKDKRVLHWCPR 186
N+ M Q KMLG DW T EY E +FT ++KGL+ K ++WCP
Sbjct: 104 NIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFT--ELYKKGLVYKKTSAVNWCPN 161
Query: 187 CETALAEHEV------RGEYKLRKD--PSIYVKFPV------------------------ 214
+T LA +V R + K+ + P ++K
Sbjct: 162 DQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKINAYADELLNDLDKLDHWPDTVKTMQR 221
Query: 215 ------EGKE-----NEY---LLIWTTTPWTLPANLAVSAHPDYDYVKVKVEFNGREEYW 260
EG E N+Y L ++TT P T ++ + + E N
Sbjct: 222 NWIGRSEGVEITFNVNDYDNTLTVYTTRPDTFMGCTYLAVRAGHPLAQKAAENNPE---- 277
Query: 261 ILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFKEKYEWAHRVIL 320
A +D+ + E+ K G + VH L E E WA
Sbjct: 278 --LAAFIDECRNTKVAEAEMATMEKKGVDTGFKAVHPLTGE--------EIPVWA----- 322
Query: 321 ADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTEGKWKGIYVKEADPK 380
A+FV +E GTG V PGH + D+E KYGL + + + ++P
Sbjct: 323 ANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPVI-------------LAADGSEPD 369
Query: 381 IIEH-LREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKDKI--IKENDEK 437
+ + L EKG L +GE F D + + DK+ + + K
Sbjct: 370 LSQQALTEKGVLFNSGE----------------FNGLDH-EAAFNAIADKLTAMGVGERK 412
Query: 438 VTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVELAVAI 497
V + ++R DW +SRQRYWG P+P+ EDG + + V L +
Sbjct: 413 VNY-----RLR---------DWGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILPEDV 458
Query: 498 EVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSG 557
++G + K PE VNG R D D + +S
Sbjct: 459 VMDGITSPI-------------KADPEWAK--------TTVNGMPALRETDTFDTFMES- 496
Query: 558 IASWASLGY--PRNKELF-----EKLW-PADFIVEGEDQVT------KWFYSQQAASIVA 603
SW Y P+ KE W P D + G + ++F+ + +
Sbjct: 497 --SWYYARYTCPQYKEGMLDSEAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMV 554
Query: 604 FDTVPYRRVAMHGYVL-------------------------DEKG--------------- 623
P +++ G VL DEKG
Sbjct: 555 NSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVY 614
Query: 624 ---DKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENLKFSWKGVEQVRRMLNILW 680
KMSKS N I P+ +VER G DT R +M++A+ L++ GVE R L +W
Sbjct: 615 TGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRVW 674
Query: 681 NVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISEVENGIESFYLTKATRA 740
+ Y D LN D L E K + V+ I++V + I R
Sbjct: 675 KL-----VYEHTAKGDVAALNVDAL--TENQKALRRDVHKTIAKVTDDI-------GRRQ 720
Query: 741 LYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIY 800
+N + + +L + +GE L + + ++R+L PFTP+I ++
Sbjct: 721 TFNTAIAAIMELMNKLAKAP--TDGEQDRAL-----MQEALLAVVRMLNPFTPHICFTLW 773
Query: 801 QNLIRPFTNVESVHMLDWPKVDEKAIDEE 829
Q L + WP DEKA+ E+
Sbjct: 774 QEL----KGEGDIDNAPWPVADEKAMVED 798
>dbj|BAB07000.1| (AP001518) leucyl-tRNA synthetase [Bacillus halodurans]
Length = 806
Score = 166 bits (416), Expect = 1e-39
Identities = 211/938 (22%), Positives = 357/938 (37%), Gaps = 218/938 (23%)
Query: 10 YDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGA-IHLGTAWNKIIKDM 68
+ +++E K +K+W EN+ ++ ++ ++ K+Y LD PY SGA +H+G D+
Sbjct: 3 FSHREIESKWQKYWEENKTFKTEEDETRE--KFYALDMFPYPSGAGLHVGHPEGYTATDI 60
Query: 69 IIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALN 128
+ R + MQGYNV G+D GLP E + I N EF
Sbjct: 61 LSRMKRMQGYNVLHPMGWDAFGLPAE---------------QYAIDTGN---SPAEFTEK 102
Query: 129 NLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCE 188
N+ Q K LG DWD T +Y + + + + KGL D+ ++WCP
Sbjct: 103 NINTFRRQIKSLGFSYDWDREVNTTDPDYYKWTQWIFIQLYNKGLAYIDEVAVNWCPALG 162
Query: 189 TALAEHEV------RGEYKLRKDP------------------------------------ 206
T LA EV RG + + + P
Sbjct: 163 TVLANEEVIDGKSERGGHPVERRPMKQWMLKITEYADRLLEDLEELDWPESIKDMQRNWI 222
Query: 207 ----SIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVKVKVEFNGREEYWIL 262
V F V+G ++ + ++TT P TL + P++ V
Sbjct: 223 GRSEGAEVTFSVDG-HDDTITVFTTRPDTLFGATYMVLAPEHKLVDAITTSE-------- 273
Query: 263 AKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFKEKYEWAHRVILAD 322
K V+ E+ K ++ +E G + Y EK + +AD
Sbjct: 274 QKQAVESYKKEVATKSDLERTELAKEKTG-----VFTGAYAINPVNGEKVP----IWIAD 324
Query: 323 FVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTEGKWKGIYVKEADPKII 382
+V + GTG + P H E D+E + + LP+ + G+ +EA
Sbjct: 325 YVLVSYGTGAIMAVPAHDERDYEFAKTFDLPIKEVVSG----------GVIEQEAYTGDG 374
Query: 383 EHLREK--GYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKDKIIKENDEKVTW 440
H+ + L K IE QW + K+ +KVT+
Sbjct: 375 PHVNSEFLNGLSKEEAIEKMI----------------QWL--------EAEKKGTKKVTY 410
Query: 441 YPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVELAVAIEV- 499
++R DW+ SRQRYWG P+P+ EDG + V +EL E+
Sbjct: 411 -----RLR---------DWLFSRQRYWGEPIPVIHWEDGTMSTVPEDELPLELPKMSEIK 456
Query: 500 -NGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGI 558
+G + + L+V++ V GK RR + + W S
Sbjct: 457 PSGTGESPLANATDWLEVVD------------------PVTGKKGRRETNTMPQWAGS-- 496
Query: 559 ASWASLGY--PRNK------ELFEKLWPADFIVEGEDQVTKWFYSQQAASIVAFD----- 605
W L Y P N+ E +K P D + G + + V +D
Sbjct: 497 -CWYYLRYIDPDNERMIADPEKLKKWLPVDIYIGGAEHAVLHLLYARFWHKVLYDLGVVP 555
Query: 606 -TVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENLKF 664
P++++ G +L E +KMSKS GN++ P+++++ G DT R Y ++ ++ +
Sbjct: 556 TKEPFQKLYNQGMILGENNEKMSKSKGNVVNPDDIIDSHGADTLRLYEMFMGPLDASIAW 615
Query: 665 SWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISE 724
S G++ RR L+ +W + V +T E+K S+
Sbjct: 616 STTGLDGARRFLDRVWRLLVDENT---------------------EEK---------SSK 645
Query: 725 VENGIESFYLTKATRALYNFVVEDLS--RWYVRLIRKRLWV-EGEDPDKLAAYYTLWKVF 781
+ NG S L +A V ED R+ V + + ++V E ++L
Sbjct: 646 IVNGEGSPELKRAYHQTVKKVTEDFEELRFNVGISQLMVYVNEAYKQEELPLDQA----- 700
Query: 782 DVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEK-AIDEELEREMEF---I 837
+ ++LL+P P++AEE++ L T + WP DE +++E+E ++ +
Sbjct: 701 EGFVKLLSPVAPHLAEELWSKLGHEGT----IAYEPWPTYDEAFLVEDEVEIVVQHNGKV 756
Query: 838 RRIVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAV 875
R V A + + R+ + +TV+K +
Sbjct: 757 RAKVVVAKDATKEQMEEAALANERVKESIDGKTVRKVI 794
>dbj|BAA28842.1| (AB008528) Valyl tRNA Synthetase [Trichomonas vaginalis]
Length = 722
Score = 162 bits (406), Expect = 2e-38
Identities = 173/790 (21%), Positives = 318/790 (39%), Gaps = 139/790 (17%)
Query: 116 ENFIKKCKEFALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLE 175
E F+++ ++ + + Q + +G + W + Y T+ + ES + +++GL+
Sbjct: 15 EYFLEEAHKWVESKSGTILSQLRDMGSSLAWKDTYYTLDEKRSESVIAAFIKLFDEGLVY 74
Query: 176 KDKRVLHWCPRCETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPAN 235
+ +R+++W +TA+++ EV EY+ + T +P +
Sbjct: 75 RSERLVNWDCALKTAISDAEV-----------------------EYITLTKRTKLNVPNH 111
Query: 236 ------LAVSAHPDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGREL 289
V H Y+ + G + +A ++ +LG+ V ++ + L
Sbjct: 112 KYPQYPFGVMTHFYYEICDKDGKKTGEKVE--IATTRLETMLGDTAVAINP-KDARYNHL 168
Query: 290 EGLRYVHILMDEYPRQKEFKEKYEWAHRVILAD--FVTLEEGTGLVHTAPGHGEEDFEVG 347
G+ YV + E P I+ D V + GTG+V PGH D+EV
Sbjct: 169 HGM-YVWHPIREVPIP-------------IIQDEILVDMNFGTGVVKVTPGHDPNDYEVY 214
Query: 348 QKYG-LPVYSPLDDQGKYTEG--KWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHC 404
+++ + + S L G G ++ G+ +A ++++ ++E+G + + E +
Sbjct: 215 KRHPEIGLISILTPDGAIAPGYGQFSGMMRFDARVEMVKWMKERGLYKEEKDHEMRLGIT 274
Query: 405 WRCKTPLIFRATDQWFLKISKVKDKIIKENDE-KVTWYPDWVKIRFDNGVRDSGDWVISR 463
R + T QWF+ + + + IK D+ ++ PD + + + W ISR
Sbjct: 275 QRGHDIVEQVITPQWFVNTTDMAARAIKAVDDGELKIVPDEFVVDWKKWHENIRPWCISR 334
Query: 464 QRYWGIPLPIWQSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGP 523
Q WG +P ++ + + G W E NGE + E K +
Sbjct: 335 QLMWGHRIPAYR-----VQIDGKWAE---------GNGEWVAAASQEEAIAKGAK----- 375
Query: 524 EDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIV 583
A ++ + + + DV+D WF S + ++ +G+P N+E + +P +
Sbjct: 376 ---------ANNVEPSRVTVEQDPDVLDTWFSSALLPFSGVGWPSNEERLNRYFPNSILE 426
Query: 584 EGEDQVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVE-- 641
G D +T W S+ + VP+ + +H V D +G KMSKSLGN+I P V+
Sbjct: 427 TGWDILTFWVSRMVMMSLTLTNKVPFHTILLHPLVRDAQGRKMSKSLGNVIDPRHVINGI 486
Query: 642 -----------------------------------RAGRDTFRFYMLWATNPWENLKFSW 666
+ G D R + +
Sbjct: 487 ELEDLVAEIENSTFDDKEKKIAIDGRKADFPNGIPQCGTDAMRLALCSFAGANRTANLNV 546
Query: 667 KGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNP-------DELPFREEDKWILSRVN 719
+ R N +WN + +L NFD K NP D DKW L +++
Sbjct: 547 SVIVSYRNFCNKMWN-----AVRFALPNFD--KFNPEDSHKDLDASKTTPLDKWALKKLS 599
Query: 720 SLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGED-PDKLAAYYTLW 778
I G++ F + A + +F ++ Y+ I+ V G+D K L+
Sbjct: 600 LAIKAATAGLQDFKMADAVNGMTHFFHDEFCSVYLEGIKP--IVNGDDAAAKEVVAAVLY 657
Query: 779 KVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREMEFIR 838
+ + +R+L PF PY+ EE++Q+L R F NVES+ + +P V+E E L ++ +
Sbjct: 658 ECIESTMRMLHPFMPYVTEELWQHLPRRF-NVESIMLAPYPLVNE----EWLNYDVSIVD 712
Query: 839 RIVEAGSAAR 848
SAAR
Sbjct: 713 TAFATASAAR 722
>sp|P73274|SYL_SYNY3 LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS)
>gi|7437530|pir||S77455 leucine--tRNA ligase (EC
6.1.1.4) - Synechocystis sp. (strain PCC 6803)
>gi|1652380|dbj|BAA17302.1| (D90905) leucyl-tRNA
synthetase [Synechocystis sp.]
Length = 869
Score = 162 bits (405), Expect = 2e-38
Identities = 209/927 (22%), Positives = 357/927 (37%), Gaps = 237/927 (25%)
Query: 10 YDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMI 69
Y+ ++E+K ++ W+E + + + D PK+Y L PY SG +H+G N I D+I
Sbjct: 5 YNAGEIEQKWQQRWAEWGLDKT--PIASDLPKFYALSMFPYPSGNLHMGHVRNYTITDVI 62
Query: 70 IRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNN 129
R + MQGY V G+D GLP E IE I + + +K N
Sbjct: 63 ARLKRMQGYQVLHPMGWDAFGLPAE-----------NAAIERGIPPKQWTEK-------N 104
Query: 130 LKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCET 189
+ M Q + LG+ +DW+ T +Y + ++ GL + + ++W P +T
Sbjct: 105 IAQMRAQLQQLGLSIDWEREVATCAPDYYRWTQWLFLEFFQAGLAYQKEATVNWDPIDQT 164
Query: 190 ALAEHEVRGEYK------------------------------------------------ 201
LA +V E +
Sbjct: 165 VLANEQVDSEGRSWRSGAMVERKLLRQWFLKITDYAEALLNDLEQLTGWPERVKLMQSHW 224
Query: 202 LRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVKVKVEFNGREEYWI 261
+ K Y++FP++ + E + ++TT P T+ V P++ KV
Sbjct: 225 IGKSVGAYLEFPIKDSQ-EKIAVFTTRPDTVYGVTYVVLAPEHPLTKVVTTAE------- 276
Query: 262 LAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFKEKYEWAHRVILA 321
+ VD+ + + + E+ + + G++ I ++ + ++ +++A
Sbjct: 277 -QQGTVDEFVAMVAKESEIERTAEDKPKRGVKTGGIAINPFNGEEI---------PILIA 326
Query: 322 DFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPL--DDQGKYTEGKWKGIYVKEADP 379
D+V E GTG V P H + DF+ Q LP+ + DD +D
Sbjct: 327 DYVLYEYGTGAVMGVPAHDQRDFKFAQDNNLPMQVVIIPDD-------------ADNSDV 373
Query: 380 KIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKDKIIKENDEKVT 439
+ E G +V + + + K K IIK ++
Sbjct: 374 NLTVAYTEAGVMVNSAQFTG---------------------MASPKAKQAIIKFAEDN-- 410
Query: 440 WYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVELAVAIEV 499
D+ + + +R DW+ISRQRYWG P+PI +D AV +
Sbjct: 411 ---DYGRAKVQYRLR---DWLISRQRYWGCPIPIIHCDDCG-------------AVPVPT 451
Query: 500 NGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFI---IKVNGKDMRRVKDVVDVWFDS 556
+ELP++ E + GP L + ++ +I GK RR D +D + DS
Sbjct: 452 KDLPVELPDNVEFSGR------GPSPLAK--LEDWINVPCPSCGKPARRETDTMDTFIDS 503
Query: 557 GIASWASLGY--PRNKEL---FEKL--W-PADFIVEG-EDQVTKWFYSQQAASIVAFDTV 607
SW L Y +N EL EK+ W P D V G E + YS+ ++A +
Sbjct: 504 ---SWYFLRYADAQNTELPFDGEKVAHWLPVDQYVGGIEHAILHLLYSRFFTKVLADRQL 560
Query: 608 -----PYRRVAMHG-------------------------YVLDEKG-------------- 623
P++++ G V+D K
Sbjct: 561 IPVKEPFQKLLTQGMVQGITYKNPTTGKYVPAKDLQTGQQVIDPKDPKDPDSGEPLQVFY 620
Query: 624 DKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENLKFSWKGVEQVRRMLNILWNVY 683
+KMSKS N + P+EV+ + G DT R ++L+ P ++L++ VE R LN +W
Sbjct: 621 EKMSKSKFNGVDPQEVLAKYGADTARMFILFKAPPEKDLEWDDADVEGQFRFLNRVWR-- 678
Query: 684 VLASTYMSLDNFDPRKLNPDEL----PFREEDKWILSRVNSLISEVENGIESFYLTKATR 739
L + Y+ + P+ L P + +K + ++ I EV + Y
Sbjct: 679 -LVTDYIGDPAGIRFAVRPETLVTNEPLTKAEKDLRRAIHGAIKEVAEDLNDDY------ 731
Query: 740 ALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEI 799
+N + ++ + LI L ++ + + LL LLAPF P++ EE+
Sbjct: 732 -QFNTAISEMMKLSNALIA---------ATDLISFPVYQEGIETLLLLLAPFAPHLTEEL 781
Query: 800 YQNLIRPFTNVESVHMLDWPKVDEKAI 826
+ L R +S+H W +VD A+
Sbjct: 782 WHRLGR----TDSIHQQAWLQVDPTAL 804
>sp|Q9YD97|SYL_AERPE LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS)
>gi|7437650|pir||H72699 probable leucyl-tRNA synthetase
APE1015 - Aeropyrum pernix (strain K1)
>gi|5104685|dbj|BAA80000.1| (AP000060) 959aa long
hypothetical leucyl-tRNA synthetase [Aeropyrum pernix]
Length = 959
Score = 156 bits (390), Expect = 1e-36
Identities = 237/960 (24%), Positives = 395/960 (40%), Gaps = 175/960 (18%)
Query: 13 KKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGP-PYVSGAIHLGTAWNKIIKDMIIR 71
K +EEK ++ W E ++ + G + +F+ P PYV+ HLG+A+ + D++ R
Sbjct: 5 KAVEEKWQERWREARLFEADPQ---PGRRKFFITFPYPYVNAYPHLGSAFTILRVDIMAR 61
Query: 72 FRTMQGYNVWRQPGYDMHGLPI-----EVKVEQALGLKTKKEI---EEKIGVENFIKKCK 123
++ M+GYNV G+ G PI V+ +KT +++ EE I +
Sbjct: 62 YKRMRGYNVLFPQGWHATGGPIVSSALRVREGDPRIIKTLRDMGIPEEDIPRFRDPRYWV 121
Query: 124 EFALNNLKIMTEQFKMLGIWMDWDNPYMTIK-----NEYIESAWFTLKRAWEKGLLEKDK 178
EF K + G+ +DW + T + +IE + L+ EKG + K +
Sbjct: 122 EFF---TKAWRRDLERYGMSIDWRREFYTTSLNPAYSRFIEWQYLKLR---EKGFVGKGR 175
Query: 179 RVLHWCPRCETALAEHEVRGEYK-LRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLA 237
+ WCP+ + + +H+ EY + ++ +KF G++ T P T+
Sbjct: 176 HPVVWCPKEQKVVGDHDRPDEYAGISPQEAVIIKF--RGRDGLVYPALTYRPETVFGVTN 233
Query: 238 VSAHPDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHI 297
+ HPD Y+ +V+ EE WI+ + + L + G + ++E +GR L G R V
Sbjct: 234 LWVHPDATYLVAEVD---GEERWIIGEQAA-RELADQGHRVVILERIEGRRLLG-RIVVN 288
Query: 298 LMD--EYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDF----------E 345
D E P V+ A FV + GTG+V + P H D+ E
Sbjct: 289 PADGREVP--------------VLPASFVRPDLGTGVVMSVPAHAPYDYVALMELKRRPE 334
Query: 346 VGQKYGLP--VYSPLD----------------------------DQGKYTE--------- 366
++YGL V L+ D+ K E
Sbjct: 335 TLREYGLEPGVVESLEPIQLIAVPRAEGLLVVEEVRRRGVESQMDREKLDEATREVYARE 394
Query: 367 ----------GKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFR-A 415
G++ G+ V EA K++E L E+G ++ + + +C RC +
Sbjct: 395 FYEGIMLETTGRFSGLKVAEAKEKVVEWLEERGAALRIYTLPQEV-YC-RCGARTHVKIV 452
Query: 416 TDQWFLKISKVKDK-IIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIW 474
DQWFL SK + K + +E ++ + P V+ F+ + DW + + G PLP W
Sbjct: 453 EDQWFLLYSKPEWKALAREAVARMEFLPGHVRRDFEAIIEALRDWAFTHKGELGTPLP-W 511
Query: 475 QSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAF 534
E +V+ S + + +A + + PE Y V E L PE ++ A
Sbjct: 512 DRE----WVIESLSDST-IYMAYYTIAKYTQHPEKY----GVEPEMLTPEVFDYVFLGA- 561
Query: 535 IIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKW-- 592
D +V SGI L R + L+ +P D + G+D +
Sbjct: 562 ------------GDPGEVSRRSGIPQ-GLLEEMRREFLY--WYPLDMRISGKDLIPNHLV 606
Query: 593 FYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYM 652
F+ +I + P R + ++G+VL G+KMSKS GN I + ++ G D R
Sbjct: 607 FFIFHHTAIFPRELWP-RAIGVNGWVL-VAGEKMSKSKGNFILLRQALDWWGADATR--- 661
Query: 653 LWATNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDK 712
WA E L + G++ ++ + L S + LD P R D+
Sbjct: 662 -WA----EVLAGADSGLDDANFEPSVADSAVSLLSQW--LDFVRENYGRPARREERWVDR 714
Query: 713 WILSRVNSLISEVENGI-ESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKL 771
W SR+NS I+ V + E+ + T A Y +++ RWY+R GE + L
Sbjct: 715 WFESRLNSTIARVTRLMEEANFKTALVEAWYK--LQESYRWYLRR------SGGEPREDL 766
Query: 772 AAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRP-FTNVESVHMLDWPKVDEKAIDEEL 830
L + +V L+APF P+ AEE ++ + R F + S WP+ DE I E+
Sbjct: 767 -----LRRFIEVQTLLIAPFAPHTAEEAWEAMGREGFASTAS-----WPEPDESKISPEV 816
Query: 831 EREMEFIRRIVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQLNAKE 890
E E ++ ++E R + L +++ E +AVE + R + KE
Sbjct: 817 EAAEETVQAVLEDA-----REVLSLIGGADTLVVTVAAEWKYRAVEAVRRARERGASMKE 871
>sp|O51267|SYL_BORBU LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS)
>gi|7437538|pir||C70131 leucine--tRNA ligase (EC
6.1.1.4) leuS - Lyme disease spirochete
>gi|2688147|gb|AAB91495.1| (AE001135) leucyl-tRNA
synthetase (leuS) [Borrelia burgdorferi]
Length = 840
Score = 152 bits (381), Expect = 2e-35
Identities = 235/998 (23%), Positives = 388/998 (38%), Gaps = 272/998 (27%)
Query: 9 EYDPKKLEEKVEKFWSENEIYRKVKE---LRKDGPKYYFLDGPPYVSG-AIHLGTAWNKI 64
+Y+ K+E+K ++FW N+ Y KV+E + K+ + Y LD PY S +H+G
Sbjct: 3 KYEFIKIEKKWQEFWDNNKTY-KVEEDPSIPKE-KRLYILDMFPYPSANGLHVGHPEGYT 60
Query: 65 IKDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKE 124
D+ R++ + G++V G+D GLP E Q G +K EE I N KK
Sbjct: 61 ATDIFGRYKLLNGFHVLHPIGFDSFGLPAENYAIQT-GTHPQKSTEENI---NKFKK--- 113
Query: 125 FALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWC 184
Q K LG DWD T + Y + + + ++KGL + + +C
Sbjct: 114 -----------QIKALGFAYDWDREIRTHEENYYKWTQWIFLQLYKKGLAYVKEMPVWYC 162
Query: 185 PRCETALAEHEV----------RGEYKLRK------------------DPSIYVKFPVEG 216
P T LA E+ RG Y + K D +++P
Sbjct: 163 PELGTVLANEEIIQTSDGPKSERGSYSVEKKYLRQWVLKITKYAERLLDDLEELEWPESV 222
Query: 217 KENEYLLIWTTTPWTLPANLAVSAHPDYDYVKVKVEFNGREE------YWILA--KALVD 268
KE + I +T + + H D K+KV F R + Y ++A L++
Sbjct: 223 KEMQRNWIGKST--GVEIEFEIEGHSD----KIKV-FTTRPDTIFGITYLVIAPENKLIE 275
Query: 269 KVLGEIGVKGEVVEEFKGRELEG-LRYVHILMDE-------YPRQKEFKEKYE-WAHRVI 319
K+ + K V++ K EL+ L + D+ Y EK W +
Sbjct: 276 KIT-KNNFKQNVLKYVKHEELKSDLNRTSLEKDKSGVFTGSYAFHPITNEKIPIWVGSYV 334
Query: 320 LADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTEGKWKGIYVKEADP 379
L + GTG V P H E DF+ +KY L + + GK
Sbjct: 335 LGTY-----GTGAVMGVPAHDERDFQFAKKYQLKILPVISKSGK---------------- 373
Query: 380 KIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKDKII------KE 433
+ EK ++ I +P F LK S+VKDK+I K+
Sbjct: 374 ---NEILEKAFVDDGISI----------NSPNEFNN-----LKNSEVKDKVIKWLTKNKK 415
Query: 434 NDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVEL 493
EKV + K+R DW+ SRQRYWG P+PI + G
Sbjct: 416 GKEKVAY-----KLR---------DWIFSRQRYWGEPIPILFDKLGN------------- 448
Query: 494 AVAIEVNGERIELPE--------SYEEKLKVIEEKLGPEDLHRP--------------YV 531
A+ +E N ++LPE + E L I++ + +D+ Y
Sbjct: 449 AIPLEENDLPLKLPEIANYKPSGTGESPLSRIKDWVNVKDMGFTRETNTMPQWAGSCWYY 508
Query: 532 DAFIIKVNGKDMRRVKDV-----VDVWFDSGIAS---------W----ASLGYPRNKELF 573
++ N K+ K + VD++ + W LGY KE F
Sbjct: 509 LRYLDPKNSKEFANKKKIEYWMPVDLYIGGAEHTVLHLLYSRFWHKVLYDLGYVNTKEPF 568
Query: 574 EKLWPADFIVEGEDQVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGD--------K 625
+KL + +T + Y ++ ++ D V + D+K + K
Sbjct: 569 KKL-------INQGIITSFSYQKENGVLIPNDQV----IEKDNKFFDKKDNKEVTQVIAK 617
Query: 626 MSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENLKFSWKGVEQVRRMLNILWNVYVL 685
MSKSL N+I P+++++ G D+ R Y ++ ++ ++ KG+ V R LN +WN
Sbjct: 618 MSKSLKNVINPDDIIKEFGADSMRIYEMFMGPLTDSKPWNTKGIIGVFRFLNKIWN---- 673
Query: 686 ASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISEVENGIESFYLTKATRALYNFV 745
L EL + I+S ++ +I +V E A A+ F+
Sbjct: 674 --------------LREKELSKENPPREIISELHKVIKKVTEDTEKLNFNTAISAMMIFI 719
Query: 746 VEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQ---N 802
E L Y + Y ++K F + +L+P+ P++AEE+++
Sbjct: 720 NELLK--YEK-----------------NYLNIFKPFII---ILSPYAPHLAEELWEYIGE 757
Query: 803 LIRPFTNVESVHMLDWPKVDEKAIDEELEREMEFIRRIVEAGSAARQRAKIKLRYPVRRI 862
L F N + WPK DE I ++ + E + +I KIK + + +
Sbjct: 758 LPSLFKNSK------WPKFDESLI---IKGKKEIVLQI---------NGKIKDKILLNK- 798
Query: 863 IIETEDETVKKAVERLNRILRDQLNAKEVKVGRVEREL 900
ET ++ +K+ ++I + LN K VK+ ++ +L
Sbjct: 799 --ETGEKELKEIAMENSKIKSNLLNKKIVKIIVIKNKL 834
>pir||F81312 leucine--tRNA ligase (EC 6.1.1.4) Cj1091c [imported] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6968525|emb|CAB73346.1| (AL139077) leucyl-tRNA
synthetase [Campylobacter jejuni]
Length = 809
Score = 151 bits (377), Expect = 5e-35
Identities = 170/725 (23%), Positives = 294/725 (40%), Gaps = 145/725 (20%)
Query: 10 YDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMI 69
Y+ +E+K +K W ENE + +L PK Y L PY SG IH+G N I D +
Sbjct: 3 YEASLIEKKWQKIWDENEYFEPKDDLNL--PKKYILSMFPYPSGRIHMGHVRNYTIGDAL 60
Query: 70 IRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNN 129
R+ G+NV G+D G+P E I+ KI K + N
Sbjct: 61 ARYYRKIGFNVLHPIGFDSFGMPAE-----------NAAIKHKI-------HPKSWTYEN 102
Query: 130 LKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCET 189
+ M ++ LG T Y + + +EKGL+ + ++WC + +T
Sbjct: 103 IAYMKKELFSLGFSFSKKRMLATSDPLYTKFEQEFFIKMFEKGLIYTKEANVNWCEQDQT 162
Query: 190 ALAEHEVRG--------EYKLRKDPSIYVKFPVEGKE-----NEYLLIWTTTPWTLPAN- 235
LA +V E +K P YVK +E E W T+ N
Sbjct: 163 VLANEQVEDGKCWRCGHEVVQKKMPGYYVKITAYAEELLKDLEELKDKWPNQVLTMQENW 222
Query: 236 ------LAVSAHPDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGREL 289
L S + D + K K + + E + A + + + ++V+ + L
Sbjct: 223 IGKSEGLEFSLNLD-EESKQKTKESSLEVFTTRADTIYGVSYIALAPEHKIVQNLLSQNL 281
Query: 290 ---EGLRYVHILMDEYPRQKEFKEKYEWAHRVI-------------LADFVTLEEGTGLV 333
+ L + ++ ++ PR+++ EK + + +A+FV + G+G V
Sbjct: 282 LNQDVLNKIKVIQNQSPRERQSSEKEGYFLGIYAIHPLSGEKIPLWVANFVLADYGSGAV 341
Query: 334 HTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTEGKWKGIYVKEADPKIIEHLREKGYLVK 393
P H E DFE KY L + + Q + + ++++ G L+
Sbjct: 342 MAVPAHDERDFEFATKYNLAIKQVIQTQ------------------ENLPYMQKLGKLIN 383
Query: 394 AGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKDKIIKENDEK-VTWYPDWVKIRFDNG 452
+ E ++ L ++ + KII + + K + KIR
Sbjct: 384 SQEFDN---------------------LDCNEARLKIISQFEAKNIGKRVVNFKIR---- 418
Query: 453 VRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEE 512
DW +SRQRYWG P+P+ + + I V ++ I LPE +
Sbjct: 419 -----DWGVSRQRYWGAPIPMIKCQSCGI-------------VPQKLENLPITLPEDVQ- 459
Query: 513 KLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKEL 572
I + P D H + + K GK+ ++ D +D +F+S SW + +++
Sbjct: 460 ----ITGEGNPLDKHPTWKNCICPKC-GKEAQKESDTLDTFFES---SWYFARFASDEKT 511
Query: 573 FE---------KLWPA--DFIVEGEDQVTKWFYS---QQAASIVAFDT--VPYRRVAMHG 616
++ K W + +I E + Y+ Q+A + + T P+ R+ G
Sbjct: 512 WQEKALDEKSVKYWMSVDQYIGGIEHAILHLLYARFFQKALRDLGYLTQNEPFDRLLTQG 571
Query: 617 YVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENLKFSWKGVEQVRRML 676
VL + G KMSKS GN++ P+E++E+ G DT R ++L+A P + L+++ VE R +
Sbjct: 572 MVLKD-GAKMSKSKGNVVDPDEIIEKYGADTARLFILFAAPPAKELEWNDDAVEGAYRFI 630
Query: 677 NILWN 681
L++
Sbjct: 631 CKLYD 635
>gi|11499997 leucyl-tRNA synthetase (leuS) [Archaeoglobus fulgidus]
>gi|3122899|sp|O30250|SYL_ARCFU LEUCYL-TRNA SYNTHETASE
(LEUCINE--TRNA LIGASE) (LEURS) >gi|7437642|pir||F69552
leucyl-tRNA synthetase (leuS) homolog - Archaeoglobus
fulgidus >gi|2650668|gb|AAB91241.1| (AE001108)
leucyl-tRNA synthetase (leuS) [Archaeoglobus fulgidus]
Length = 932
Score = 150 bits (376), Expect = 6e-35
Identities = 229/1000 (22%), Positives = 399/1000 (39%), Gaps = 212/1000 (21%)
Query: 11 DPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGP-PYVSGAIHLGTAWNKIIKDMI 69
D + +EEK +K W ++ I+ E + + +FL P PY++G +H G I D
Sbjct: 3 DFRIIEEKWQKAWEKDRIF----ESDPNEKEKFFLTIPYPYLNGNLHAGHTRTFTIGDAF 58
Query: 70 IRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIE-----EKIGVENFI----- 119
R+ M+GYNV G+ + G PI + + + + + ++ IE + +E+ +
Sbjct: 59 ARYMRMKGYNVLFPLGFHVTGTPI-IGLAELIAKRDERTIEVYTKYHDVPLEDLLQLTTP 117
Query: 120 -KKCKEFALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEY---IESAWFTLKRAWEKGLLE 175
K + F+ L+ + K +G +DW + T EY IE ++ LK E GL+
Sbjct: 118 EKIVEYFSREALQAL----KSIGYSIDWRRVFTTTDEEYQRFIEWQYWKLK---ELGLIV 170
Query: 176 KDKRVLHWCPRCETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPAN 235
K + +CP + + +H++ + +KF +E + + T P T+
Sbjct: 171 KGTHPVRYCPHDQNPVEDHDLLAGEEATIVEFTVIKFRLEDGDLIFPCA-TLRPETVFGV 229
Query: 236 LAVSAHPDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYV 295
+ P YV +V+ E W ++K +K L K ++EE + G +
Sbjct: 230 TNIWVKPT-TYVIAEVD----GEKWFVSKEAYEK-LTYTEKKVRLLEEVDASQFFGKYVI 283
Query: 296 HILMDEYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHG----------EEDFE 345
L++ ++ A+FV + TG+V + P H + D E
Sbjct: 284 VPLVNRKVP-------------ILPAEFVDTDNATGVVMSVPAHAPFDLAAIEDLKRDEE 330
Query: 346 VGQKYGLP----------VYSPLDDQG-------------------------------KY 364
KYG+ V D +G +Y
Sbjct: 331 TLAKYGIDKSVVESIKPIVLIKTDIEGVPAEKLIRELGVKSQKDKELLDKATKTLYKKEY 390
Query: 365 TEG-------KWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKY---PHCWRCKTPLIFR 414
G + G+ V EA ++ E L + G G++ +++ P RC T + +
Sbjct: 391 HTGIMLDNTMNYAGMKVSEAKERVHEDLVKLGL----GDVFYEFSEKPVICRCGTKCVVK 446
Query: 415 AT-DQWFLKIS--KVKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPL 471
DQWFL S + K+K++ EK+ PD+ K F N + D +R++ G +
Sbjct: 447 VVRDQWFLNYSNREWKEKVLNHL-EKMRIIPDYYKEEFRNKIEWLRDKACARRKGLGTRI 505
Query: 472 PIWQSE-------DGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPE 524
P W E D IY + +A +N ++ E L + LG
Sbjct: 506 P-WDKEWLIESLSDSTIY-------MAYYILAKYINAGLLKAENMTPEFLDYV--LLGKG 555
Query: 525 DLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVE 584
++ + A K++ + +++++D + W+ P D
Sbjct: 556 EVGKV---AEASKLSVELIQQIRDDFEYWY-----------------------PVDLRSS 589
Query: 585 GEDQVTKW--FYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVER 642
G+D V FY +I D P R +A++GYV E G KMSKS G ++ + V++
Sbjct: 590 GKDLVANHLLFYLFHHVAIFPPDKWP-RAIAVNGYVSLE-GKKMSKSKGPLLTMKRAVQQ 647
Query: 643 AGRDTFRFYMLWATNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNP 702
G D R Y+L A + + + VE + L +N+ + Y+
Sbjct: 648 YGADVTRLYILHAAEYDSDADWKSREVEGLANHLRRFYNL--VKENYLK----------- 694
Query: 703 DELPFREEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLW 762
+ D+W++SR+ I EV +++ +A A + ++ D+ RWY+R + L
Sbjct: 695 EVGELTTLDRWLVSRMQRAIKEVREAMDNLQTRRAVNAAFFELMNDV-RWYLRRGGENLA 753
Query: 763 VEGEDPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVD 822
+ + D ++LLAPF P+I EE++ + ++ES +P+ D
Sbjct: 754 I----------------ILDDWIKLLAPFAPHICEELWHLKHDSYVSLES-----YPEYD 792
Query: 823 EKAIDEELEREMEFIRRIVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRIL 882
E +DEE ER E++R +VE Q K + I ED VK A
Sbjct: 793 ETRVDEEAERIEEYLRNLVE----DIQEIKKFVSDAKEVYIAPAEDWKVKAA-------- 840
Query: 883 RDQLNAKEVKVGRVERELTIKPNFAKLGPEFKGDAKIIAK 922
++ A+ VG ++L KLG E K I K
Sbjct: 841 --KVVAESGDVGEAMKQLMQDEELRKLGKEVSNFVKKIFK 878
>gb|AAG10490.1|AF279106_52 (AF279106) predicted leucyl-tRNA synthetase (leuS) [uncultured
proteobacterium EBAC31A08]
Length = 804
Score = 150 bits (375), Expect = 8e-35
Identities = 188/884 (21%), Positives = 342/884 (38%), Gaps = 211/884 (23%)
Query: 9 EYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDM 68
EY+P ++E+ ++ W + + ++ + R+ K+Y L PY SG +H+G N I D+
Sbjct: 4 EYNPSQIEKTIQDEWLKEDKFKANPDGRE---KFYCLSMFPYPSGKLHMGHVRNYTIGDV 60
Query: 69 IIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALN 128
I R++ M +NV++ G+D GLP E I K+ K++
Sbjct: 61 ISRYKRMNNFNVFQPMGWDAFGLPAE-----------NAAIANKVSP-------KDWTNQ 102
Query: 129 NLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKR--------------------- 167
N++ M +Q LG+ DW T + EY + K+
Sbjct: 103 NIEHMKQQLISLGLGYDWSKELRTCEPEYYKWEQLIFKKFYDKGLVYRKKSLVNWDPVDE 162
Query: 168 ------------AWEKGLLEKDKRVLHWCPRCE-------TALAEHEVRGEYK------L 202
W G + K + W + T+L E + K +
Sbjct: 163 TVLANEQVIDGKGWRSGAQVEIKEIDQWFIKITDYAEELLTSLDEVDWPENVKTMQRNWI 222
Query: 203 RKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVKVKVEFNGREEYWIL 262
K +K+ +E ++ L +++T P T+ ++ P++ + + + N
Sbjct: 223 GKSQGAEIKYMIEDSDDS-LKVFSTRPDTIFGVSFLAISPNHS-ISIGLSKNNES----- 275
Query: 263 AKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFKEKYEWAHRVILAD 322
K ++K + ++ + K G+ +H + K+K V + +
Sbjct: 276 IKDFLNKCKEVKAAEADMAKAEKLGINSGMHVIHPIT---------KKKIP----VWIGN 322
Query: 323 FVTLEEGTGLVHTAPGHGEEDFEVGQKYGL--PVYSPLDDQGKYTEGKWKGIYVKEADPK 380
FV L+ GTG+V P H + DFE KY L P D+ +
Sbjct: 323 FVLLDYGTGVVMGVPAHDQRDFEFASKYNLEIPQVISFDNNNELP--------------- 367
Query: 381 IIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKDKIIKENDEKVTW 440
+ +KG L+ + + + +D+ L+I +KD E++
Sbjct: 368 ----VVQKGKLINSDKYDGM--------------DSDEASLEI--IKDLADANLGEQLIQ 407
Query: 441 YPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVELAVAIEVN 500
+ ++R DW +SRQRYWG P+P+ E+GE V+ + L E+
Sbjct: 408 F----RLR---------DWGVSRQRYWGCPIPVVY-ENGEPRVIDEKDMPIVLP---ELK 450
Query: 501 GERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIAS 560
+P S E I ++L +R D D + DS S
Sbjct: 451 KNSAPIPLSQNEDFYNISDRL----------------------KRETDTFDTFMDS---S 485
Query: 561 WASLGYPRNK---ELFEK---LW-PADFIVEGEDQV------TKWFYSQQAASIVAFDTV 607
W + + E+F+K W P D + G + +++F+ +
Sbjct: 486 WYYARFTSSDNADEMFDKNSKYWLPVDLYIGGIEHAILHLLYSRFFHKALRDMDLVEGNE 545
Query: 608 PYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENLKFSWK 667
P++++ G VL + G KMSKS GN + P+ +E+ G DT R YM++ P ++L++S
Sbjct: 546 PFKKLLTQGMVLKD-GAKMSKSKGNTVDPQSYIEKYGADTVRLYMMFTAPPEQSLEWSES 604
Query: 668 GVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISEVEN 727
VE R + +WN L S +D +P+ + E+ R + ++ + +V N
Sbjct: 605 SVEGASRFMKKIWN---LVSNRKFIDLEEPKDPSKQEVELRRKS-------HNTLKKVTN 654
Query: 728 GIESFYLTKATRA----LYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFDV 783
E+ Y A L NF+ + E ++ Y L + +
Sbjct: 655 DFETRYSFNTAIASIMELVNFIPDSFK---------------EGNASISNQYCLNEAIII 699
Query: 784 LLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAID 827
+L+ L P P+I++ ++ N F E WP + E+ ++
Sbjct: 700 ILKTLNPIAPHISQHLWNNFYFDFAQEEIES--SWPVLREELLE 741
>sp|O27552|SYL_METTH LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS)
>gi|7437646|pir||B69068 leucine--tRNA ligase (EC
6.1.1.4) - Methanobacterium thermoautotrophicum (strain
Delta H) >gi|2622626|gb|AAB85983.1| (AE000911)
leucyl-tRNA synthetase [Methanobacterium
thermoautotrophicum]
Length = 937
Score = 150 bits (374), Expect = 1e-34
Identities = 219/985 (22%), Positives = 384/985 (38%), Gaps = 205/985 (20%)
Query: 15 LEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRT 74
+E K W + I++ + D K + PY SGA+H+G + D+ RF+
Sbjct: 3 IERKWRDRWRDAGIFQADPD---DREKIFLTVAYPYPSGAMHIGHGRTYTVPDVYARFKR 59
Query: 75 MQGYNV-----WRQPGYDMHGLPIEVKVEQALGLKTKKEIE-------EKIGVENFIKKC 122
MQGYNV W G + G+ ++ + LK +E+ E+ +I
Sbjct: 60 MQGYNVLFPMAWHVTGAPVIGIARRIQRKDPWTLKIYREVHRVPEDELERFSDPEYI--V 117
Query: 123 KEFALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLH 182
+ F+ +M + +G +DW + T Y + +++ + GL+ K +
Sbjct: 118 EYFSREYRSVMED----MGYSIDWRREFKTTDPTYSRFIQWQIRKLRDLGLVRKGAHPVK 173
Query: 183 WCPRCETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHP 242
+CP CE + +H++ + + +KF + + YL+ T P T+ + +P
Sbjct: 174 YCPECENPVGDHDLLEGEGVAINQLTLLKFKL---GDSYLVAATFRPETIYGATNLWLNP 230
Query: 243 DYDYVKVKVEFNGREEYWILAKALVDKVLG---EIGVKGEVVEEFKGRELEGLRYVHILM 299
D DYV+V+ G EE WI+++A VD + ++ V G+V +L G+ + +
Sbjct: 231 DEDYVRVE---TGGEE-WIISRAAVDNLSHQKLDLKVSGDV----NPGDLIGMCVENPVT 282
Query: 300 DEYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDF----------EVGQK 349
+ H ++ A FV E TG+V + P H DF E+ ++
Sbjct: 283 GQ-------------EHPILPASFVDPEYATGVVFSVPAHAPADFIALEDLRTDHELLER 329
Query: 350 YGL--------PV-YSPLDDQGKYTEGK-------------------------------- 368
YGL PV +D G++ +
Sbjct: 330 YGLEDVVADIEPVNVIAVDGYGEFPAAEVIEKFGVRNQEDPRLEDATGELYKIEHARGVM 389
Query: 369 ------WKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRA-TDQWFL 421
+ G+ V EA I + L+++G + E + P RC + R DQWF+
Sbjct: 390 SSHIPVYGGMKVSEAREVIADELKDQGLADEMYEFAER-PVICRCGGRCVVRVMEDQWFM 448
Query: 422 KISKVKDKIIKEND-EKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGE 480
K S K + + + P+ V+ F+ + DW SR+ G LP
Sbjct: 449 KYSDDAWKDLAHRCLDGMKIIPEEVRANFEYYIDWLNDWACSRRIGLGTRLP-------- 500
Query: 481 IYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNG 540
W E + I E L ++ Y + I
Sbjct: 501 ------WDE-------------------------RWIIEPLTDSTIYMAY---YTIAHRL 526
Query: 541 KDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTK--WFYSQQA 598
++M ++ D +FD+ I S + +E F +P D+ + +D + F+
Sbjct: 527 REM-DAGEMDDEFFDA-IFLDDSGTFEDLREEFRYWYPLDWRLSAKDLIGNHLTFHIFHH 584
Query: 599 ASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNP 658
++I P R + G L E G+KMS S GN+I + +E+ G D R +++ + P
Sbjct: 585 SAIFPESGWP-RGAVVFGMGLLE-GNKMSSSKGNVILLRDAIEKHGADVVRLFLMSSAEP 642
Query: 659 WENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREED---KWIL 715
W++ F W+ E + I W LD R + + P E +W++
Sbjct: 643 WQD--FDWRESEVIGTRRRIEWFREFGERVSGILDG---RPVLSEVTPAEPESFIGRWMM 697
Query: 716 SRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYY 775
++N I E +ESF KA + + +D+ + R VEG D++ +
Sbjct: 698 GQLNQRIREATRALESFQTRKAVQEALYLLKKDVDHYLKR-------VEGRVDDEVKS-- 748
Query: 776 TLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKV-------DEKAIDE 828
L V +RL+APF PY AEE+++ + V WP D + +E
Sbjct: 749 VLANVLHAWIRLMAPFIPYTAEEMWER----YGGEGFVAEAPWPDFSDDAESRDVQVAEE 804
Query: 829 ELEREMEFIRRIVEAGSAARQRAKI----KLRYPVRRIIIETE----------------D 868
++ + I+ I++ + +R I K ++ V R+ E
Sbjct: 805 MVQNTVRDIQEIMKILGSTPERVHIYTSPKWKWDVLRVAAEVGKLDMGSIMGRVSAEGIH 864
Query: 869 ETVKKAVERLNRILRDQLNAKEVKV 893
+ +K+ E + RI+RD L EV V
Sbjct: 865 DNMKEVAEFVRRIIRD-LGKSEVTV 888
>gb|AAK40902.1| Leucyl-tRNA synthetase (leuS-2) [Sulfolobus solfataricus]
Length = 944
Score = 148 bits (371), Expect = 2e-34
Identities = 230/999 (23%), Positives = 399/999 (39%), Gaps = 177/999 (17%)
Query: 23 WSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRTMQGYNVWR 82
W E++IY K PK++ PY + H+G + D++ R++ M+GYNV
Sbjct: 12 WEEDKIYESNPNPSK--PKFFTTVAFPYPNSPWHIGHGRTYVTGDILARYKRMRGYNVLF 69
Query: 83 QPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGV----ENFIKKCKE--FALNNLKI-MTE 135
+ G PI + + A+ K+ IE + + I + + F N K +
Sbjct: 70 PMAFHYTGTPI-MAMADAIAKGDKELIETFKDIYEISPDVIPRMSDPLFMANYFKEDIKA 128
Query: 136 QFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHE 195
+ +G+ +DW + TI E+ + + KG + KD + WCP + H+
Sbjct: 129 SMREIGLGIDWRREFTTIDPEFSSFVTWQFHKLQSKGYIVKDTHPVGWCPVHHIPVGMHD 188
Query: 196 VRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVKVKVEFNG 255
+G+ + + + F E T P T+ A+ +P YV + G
Sbjct: 189 TKGDVEPEIGEFVLIYF---NSEKGIFPAATLRPETIFGATALWINPSEMYVVASML--G 243
Query: 256 REEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFKEKYEWA 315
++ IL++ K+ +I E+ E+ KG +L GL+ + + ++
Sbjct: 244 KK--MILSEKAAAKLSFQID-DIEIEEKIKGSKLVGLKVENPITGKHIA----------- 289
Query: 316 HRVILADFVTLEEGTGLVHTAPGHG-------EEDFEVGQKYGLPVYS------------ 356
V+ ADFV + GTG+V + P H ++ F+ +PV +
Sbjct: 290 --VLGADFVDVSLGTGVVMSVPAHAPFDYYYSKKTFKNNNIEIIPVITVEGLGNALAKDV 347
Query: 357 -----PLDDQG-----------KYTEGKWK-------------------GIYVKEADPKI 381
P D+ +Y +G + G+ V + I
Sbjct: 348 VEKNNPKSDEDLKKLTEYVYRTEYNKGVLRSDLGNLIREEYRNELKSLGGLPVPKGRELI 407
Query: 382 IEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRAT-DQWFLKISKVKDK-IIKENDEKVT 439
L KG K E+ +K +C RC T ++ + DQWFL S + K + +++ K+
Sbjct: 408 TNFLISKGLGRKIFEVMNKPVYC-RCGTEIVVKILKDQWFLDYSNKEWKELARKSLSKIN 466
Query: 440 WYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVELAVAIEV 499
P+ + F+ + +R R G PLP W + W IE
Sbjct: 467 VIPEESRKDFEFTIEWLEKRACARTRGLGTPLP-WDKK---------W--------IIES 508
Query: 500 NGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIA 559
+ Y K+ + KL P L + + D ++ + + ++ +GI
Sbjct: 509 LSDSTIYMAYYTISHKIKQYKLSPSKLTQEFWDYVMLGIGNLE--------EISEKTGIP 560
Query: 560 SWASLGYPRNKELFEKLWPADFIVEGEDQVTKW--FYSQQAASIVAFDTVPYRRVAMHGY 617
S + +E F +P D G+D + F+ A+I + P + +A++G
Sbjct: 561 SNIIKEF---REEFLYWYPLDIRHSGKDLIPNHLTFFIFNHAAIFQENLWP-KAIAVNGL 616
Query: 618 VLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENLKFSWKGVEQVRRMLN 677
VL E G KMSKSL NII + ++ G D R + + ++ FS V+ V L
Sbjct: 617 VLYE-GKKMSKSLRNIIPLRKGLKMYGVDVMRIAVSSTADMGSDVNFSESLVKTVGETLR 675
Query: 678 ILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISEVENGIESFYLTKA 737
++ ++ SLDN+ D L F E KW+LSR+ + S +E+ L A
Sbjct: 676 KMYELF------KSLDNY-----TGDILGFPE--KWLLSRIYEITSSTTRHMEALELRDA 722
Query: 738 TRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFDVLLRLLAPFTPYIAE 797
L DL ++ + EG + + L +V + L+L+ PF P++AE
Sbjct: 723 VNELLFVFSSDLDEYFGMVS-----AEGREANNKV----LREVLTIWLKLITPFAPHLAE 773
Query: 798 EIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREMEFIRRIVEAGSAARQRAKIKLRY 857
EI+ +++ T + + WP+V+ +DE E E+++RIVE R I
Sbjct: 774 EIWHEILKQKTYIVNE---GWPEVEGSKMDELTLLEHEYMKRIVE---DIRSILNIFKGT 827
Query: 858 PVRRIIIETEDETVKKAVERLNRILRDQLNAKEVKVGRVERELTIKPNFAKLGPEFKGDA 917
P I D R +LRD + A G++++ + I P+ + DA
Sbjct: 828 PKLIKIYALND-------SRYMELLRDAIVAN----GQMKKFMDIHK------PKSREDA 870
Query: 918 KIIAKWINENGRELYEKGELTVEIDGKTFHLTREHIIVE 956
+I+ K NE ++EID K L + I E
Sbjct: 871 RILQKIFNE-----------SLEIDDKMKKLVTNYNINE 898
>emb|CAB57710.1| (Y18930) isoleucyl-trna synthetase [Sulfolobus solfataricus]
Length = 944
Score = 148 bits (371), Expect = 2e-34
Identities = 230/999 (23%), Positives = 399/999 (39%), Gaps = 177/999 (17%)
Query: 23 WSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRTMQGYNVWR 82
W E++IY K PK++ PY + H+G + D++ R++ M+GYNV
Sbjct: 12 WEEDKIYESNPNPSK--PKFFTTVAFPYPNSPWHIGHGRTYVTGDILARYKRMRGYNVLF 69
Query: 83 QPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGV----ENFIKKCKE--FALNNLKI-MTE 135
+ G PI + + A+ K+ IE + + I + + F N K +
Sbjct: 70 PMAFHYTGTPI-MAMADAIAKGDKELIETFKDIYEISPDVIPRMSDPLFMANYFKEDIKA 128
Query: 136 QFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHE 195
+ +G+ +DW + TI E+ + + KG + KD + WCP + H+
Sbjct: 129 SMREIGLGIDWRREFTTIDPEFSSFVTWQFHKLQSKGYIVKDTHPVGWCPVHHIPVGMHD 188
Query: 196 VRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVKVKVEFNG 255
+G+ + + + F E T P T+ A+ +P YV + G
Sbjct: 189 TKGDVEPEIGEFVLIYF---NSEKGIFPAATLRPETIFGATALWINPSEMYVVASML--G 243
Query: 256 REEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFKEKYEWA 315
++ IL++ K+ +I E+ E+ KG +L GL+ + + ++
Sbjct: 244 KK--MILSEKAAAKLSFQID-DIEIEEKIKGSKLVGLKVENPITGKHIA----------- 289
Query: 316 HRVILADFVTLEEGTGLVHTAPGHG-------EEDFEVGQKYGLPVYS------------ 356
V+ ADFV + GTG+V + P H ++ F+ +PV +
Sbjct: 290 --VLGADFVDVSLGTGVVMSVPAHAPFDYYYSKKTFKNNNIEIIPVITVEGLGNALAKDV 347
Query: 357 -----PLDDQG-----------KYTEGKWK-------------------GIYVKEADPKI 381
P D+ +Y +G + G+ V + I
Sbjct: 348 VEKNNPKSDEDLKKLTEYVYRTEYNKGVLRSDLGNLIREEYRNELKSLGGLPVPKGRELI 407
Query: 382 IEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRAT-DQWFLKISKVKDK-IIKENDEKVT 439
L KG K E+ +K +C RC T ++ + DQWFL S + K + +++ K+
Sbjct: 408 TNFLISKGLGRKIFEVMNKPVYC-RCGTEIVVKILKDQWFLDYSNKEWKELARKSLSKIN 466
Query: 440 WYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVELAVAIEV 499
P+ + F+ + +R R G PLP W + W IE
Sbjct: 467 VIPEESRKDFEFTIEWLEKRACARTRGLGTPLP-WDKK---------W--------IIES 508
Query: 500 NGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIA 559
+ Y K+ + KL P L + + D ++ + + ++ +GI
Sbjct: 509 LSDSTIYMAYYTISHKIKQYKLSPSKLTQEFWDYVMLGIGNLE--------EISEKTGIP 560
Query: 560 SWASLGYPRNKELFEKLWPADFIVEGEDQVTKW--FYSQQAASIVAFDTVPYRRVAMHGY 617
S + +E F +P D G+D + F+ A+I + P + +A++G
Sbjct: 561 SNIIKEF---REEFLYWYPLDIRHSGKDLIPNHLTFFIFNHAAIFQENLWP-KAIAVNGL 616
Query: 618 VLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENLKFSWKGVEQVRRMLN 677
VL E G KMSKSL NII + ++ G D R + + ++ FS V+ V L
Sbjct: 617 VLYE-GKKMSKSLRNIIPLRKGLKMYGVDVMRIAVSSTADMGSDVNFSESLVKTVGETLR 675
Query: 678 ILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISEVENGIESFYLTKA 737
++ ++ SLDN+ D L F E KW+LSR+ + S +E+ L A
Sbjct: 676 KMYELF------KSLDNY-----TGDILGFPE--KWLLSRIYEITSSTTRHMEALELRDA 722
Query: 738 TRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFDVLLRLLAPFTPYIAE 797
L DL ++ + EG + + L +V + L+L+ PF P++AE
Sbjct: 723 VNELLFVFSSDLDEYFGMVS-----AEGREANNKV----LREVLTIWLKLITPFAPHLAE 773
Query: 798 EIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREMEFIRRIVEAGSAARQRAKIKLRY 857
EI+ +++ T + + WP+V+ +DE E E+++RIVE R I
Sbjct: 774 EIWHEILKQKTYIVNE---GWPEVEGSKMDELTLLEHEYMKRIVE---DIRSILNIFKGT 827
Query: 858 PVRRIIIETEDETVKKAVERLNRILRDQLNAKEVKVGRVERELTIKPNFAKLGPEFKGDA 917
P I D R +LRD + A G++++ + I P+ + DA
Sbjct: 828 PKLIKIYALND-------SRYMELLRDAIVAN----GQMKKFMDIHK------PKSREDA 870
Query: 918 KIIAKWINENGRELYEKGELTVEIDGKTFHLTREHIIVE 956
+I+ K NE ++EID K L + I E
Sbjct: 871 RILQKIFNE-----------SLEIDDKMKKLVTNYNINE 898
>sp|P57519|SYL_BUCAI LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS)
>gi|10039108|dbj|BAB13142.1| (AP001119) leucyl-tRNA
synthetase [Buchnera sp. APS]
Length = 859
Score = 145 bits (362), Expect = 3e-33
Identities = 204/913 (22%), Positives = 364/913 (39%), Gaps = 228/913 (24%)
Query: 8 REYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKD 67
+EY PKK+E V++FW +N+ + ++ +K+ KYY L PY SG +H+G N I D
Sbjct: 3 KEYSPKKIENYVQEFWKKNKTFEVKEDPKKE--KYYCLPMLPYPSGKLHMGHVRNYTISD 60
Query: 68 MIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFAL 127
+I R++ M G NV + G+D GLP E E A+ T +
Sbjct: 61 VISRYQRMLGKNVLQPMGWDAFGLPAE---EAAIRNNTDP---------------FSWTQ 102
Query: 128 NNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRC 187
N+K M +Q + LG DW T EY + + +EK L+ K +++WC
Sbjct: 103 KNIKYMKKQLQSLGFSYDWSREITTCHPEYYHWEQWFFTKLYEKKLVYKKNSLVNWCSYD 162
Query: 188 ETALAEHEV--------RGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVS 239
+T LA +V + + ++++ P ++K E+ Y + T W P N+
Sbjct: 163 KTVLANEQVIDGCCWRCQNKIRIKQIPQWFIKIR-NYAESLYQDLKKLTHW--PENVKNM 219
Query: 240 AHPDYDYVK----VKVEFNGREEYWILAKALVDKVLG--------------EIGVKGEVV 281
+K FN ++ + + L D ++G + K E++
Sbjct: 220 QRNWIGRIKGFEITLNVFNTCQKLKVFTQRL-DLLMGVTYISISSCHKLSINLSKKNELI 278
Query: 282 EEFKGRELEGLRYVHILMDEYPRQKEFKEKYEWAHR--------------VILADFVTLE 327
++F ++ RY+ +++++K KY + + +++ +E
Sbjct: 279 KKF----IKKYRYI-------SQEEQYKVKYTGINTNLFVVHPITKKTIPIWISNATHIE 327
Query: 328 EGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTEGKWKGIYVKEADPKI-IEHLR 386
GT V + PGH E D+ K L + K+ +PK+ L
Sbjct: 328 YGTNAVLSIPGHNENDWNFAVKNNLKI-------------KYVIFNPDHQEPKLYTSFLD 374
Query: 387 EKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKV--KDKIIKENDEKVTWYPDW 444
KG L + E + T+ KI K+ K KI+KE
Sbjct: 375 IKGTLFNSQEFNGLN----------LKDGTE----KIKKILYKKKILKE----------- 409
Query: 445 VKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVELAVAIEVNGERI 504
KI + DW ISRQRYWG P+P+ + ++G++ + I N +
Sbjct: 410 -KINY-----KLQDWCISRQRYWGTPIPMAKFKNGKM-------------IPIPENQLPV 450
Query: 505 ELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASL 564
LP+ + ++++ + + + + + FI +GK R D D + +S SW
Sbjct: 451 VLPK-IRKNTNLLQQAI---NFNSKWAEIFI---HGKHAIREIDTFDTFMES---SWYYA 500
Query: 565 GYP-------RNKELFEKLW-PADFIVEG-EDQVTKWFYSQ------QAASIVAFDTVPY 609
Y + K W P D + G E + Y + + +V FD P
Sbjct: 501 RYTCPNFNTGMIDSIASKYWLPVDQYIGGIEHAIMHLMYFRFYHKLLRDFKLVDFDE-PV 559
Query: 610 RRVAMHGYVLDE-------------------------KGD------------------KM 626
+ + G VL E KG+ KM
Sbjct: 560 KNLLCQGMVLSEAFYKIDSNSQRKWFNSSSVLIKRNTKGEIIESHTQKGEKLIYAGMIKM 619
Query: 627 SKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENLKFSWKGVEQVRRMLNILWNVYVLA 686
SKS N I PE +++R G DT R +++++ +L++ G++ + R L LW +L
Sbjct: 620 SKSKNNGIEPELIIQRYGADTIRLFIMFSAPVESDLEWKESGLKGIYRFLKKLW---MLI 676
Query: 687 STYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVV 746
Y+ + N +K+N D L ++ + + +++ I++V + I R +N +
Sbjct: 677 FNYIDIKN-THKKINFDFLNHQQSE--LRYQLHKTIAKVSDDI-------GRRQTFNTAI 726
Query: 747 EDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRP 806
++ + +L + + E+ DK +L ++++L PFTP+ ++
Sbjct: 727 SEIMKLVNQLSKAPI---KEEQDKSIMRESL----ICIIKMLYPFTPHFCFFVWNY---- 775
Query: 807 FTNVESVHMLDWP 819
F N S+ WP
Sbjct: 776 FNNHSSIDNEKWP 788
>pir||T27465 hypothetical protein Y87G2A.m - Caenorhabditis elegans
Length = 634
Score = 137 bits (342), Expect = 6e-31
Identities = 133/581 (22%), Positives = 241/581 (40%), Gaps = 77/581 (13%)
Query: 23 WSENEIYRKVKELRKDGPKYYFLDG------PPYVSGAIHLGTAWNKIIKDMIIRFRTMQ 76
W E E + K + + K P D PP V+G +H+G A ++D I RF M
Sbjct: 95 WWEKEGFFKPEYIDKLNPGSNPADSFTVCIPPPNVTGNLHVGHALATTVEDTITRFNRMH 154
Query: 77 GYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIMTEQ 136
G PG D G+ +V VE+ L + + +G + F ++ + ++ +Q
Sbjct: 155 GKRTLFNPGCDHAGIATQVVVEKRLK-RERGLTRHDLGRDRFNQEVWHWKNEKGDVIYDQ 213
Query: 137 FKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHEV 196
F+ LG +DWD T+ + + R E G + + R+++W +A+++ EV
Sbjct: 214 FRKLGASVDWDRAVFTMDPKMCRAVTEAFIRMHESGTIYRSNRLVNWSCALRSAISDIEV 273
Query: 197 RGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVKVKVEFNGR 256
K S + P K+ E+ ++ + Y + G
Sbjct: 274 D---KKELTGSTLIAVPGYDKKIEFGVL-----------------NSFAY-----KIQGS 308
Query: 257 EEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFKEKYEWAH 316
+E +++ ++ +LG+ GV ++ + + L G + +H + +
Sbjct: 309 DEEIVVSTTRIETMLGDSGVAVHPDDQ-RYKHLVGKQCIHPFIPT-------------RN 354
Query: 317 RVILAD-FVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTEG--KWKGIY 373
I AD FV +E GTG V P H D+EVG + LP ++ + D G ++G ++ G+
Sbjct: 355 LPIFADSFVEMEFGTGAVKITPAHDHNDYEVGIRQNLPFHNCITDDGLISQGCGEFSGMK 414
Query: 374 VKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKDKIIKE 433
+A +IE L+EKG + P C R K + QW++K + + +K +
Sbjct: 415 RFDARTAVIEALKEKGLYRGKEDNPMVVPTCSRSKDVIEPILKPQWYVKCAHMAEKAVAA 474
Query: 434 -NDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVE 492
+ + P++ K ++ + S DW ISRQ +WG +P + +
Sbjct: 475 VANGDLQIIPEFHKATWNRWLESSRDWCISRQLWWGHRIPAYYISFAD------------ 522
Query: 493 LAVAIEVNGERIELPE-SYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVD 551
G LPE +Y + +E L +A I+ ++ +DV+D
Sbjct: 523 --------GREQPLPEENYWVSARTEQEALAKAAQKFQVPEAEIL------LKWDEDVLD 568
Query: 552 VWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKW 592
WF SG+ +A G+P + + +P + G D + W
Sbjct: 569 TWFSSGMWPFAVFGWPDATKDMDLFFPGAVLETGHDILFFW 609
>sp|Q9ZJ63|SYL_HELPJ LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS)
>gi|7437531|pir||G71805 leucine--tRNA ligase (EC
6.1.1.4) - Helicobacter pylori (strain J99)
>gi|4156066|gb|AAD07021.1| (AE001567) LEUCYL-TRNA
SYNTHETASE [Helicobacter pylori J99]
Length = 806
Score = 134 bits (335), Expect = 4e-30
Identities = 206/917 (22%), Positives = 353/917 (38%), Gaps = 198/917 (21%)
Query: 15 LEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRT 74
+E+K ++FW +N+ + + PK Y L PY SG IH+G N I D + R+
Sbjct: 6 IEKKWQEFWWKNKSFEPKDDFNL--PKKYILSMLPYPSGEIHMGHVRNYTIGDALARYYR 63
Query: 75 MQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIMT 134
+ YNV G+D G+P E K G+ K + N++ M
Sbjct: 64 LHHYNVLHPMGFDSFGMPAE-------------NAAIKHGIHP-----KTWTYENIEAMQ 105
Query: 135 EQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEH 194
++F+ LG + + T +Y + WEKGL+ + K +L+WCP +T LA
Sbjct: 106 KEFEALGFSFSKNREFATSDPDYTKFEQQFFIDLWEKGLIYRKKAMLNWCPNDKTVLANE 165
Query: 195 EVRGEYKLRKDPSI--------YVKF---------PVEGKENEYLLIWTTTPWTLPAN-L 236
+V R D + Y+K +E EN W + T+ N +
Sbjct: 166 QVIDGRCWRCDTEVIQKELYQYYLKITNYAEELLKDLETLENH----WPSQVLTMQKNWI 221
Query: 237 AVSAHPDYDY------VKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEE-FKGREL 289
S+ + + +K E + A + I + +VE K
Sbjct: 222 GKSSGLQFGFKIADECLKACNNIQEIEVFTTRADTIYGVTYIAIAPEHPLVEHAIKRVSQ 281
Query: 290 EGLRYVHILMDEYPRQKEFKEKYEWAH------------RVILADFVTLEEGTGLVHTAP 337
E + + +++ R++ ++K + V +A+F G+G + P
Sbjct: 282 EDSKMIKAILNTTQRERALEKKGAFLGIYAIHPLTKQKIPVWVANFALANYGSGALMGVP 341
Query: 338 GHGEEDFEVGQKYGLPVYSPLDDQGKYTEGKWKGIYVKEADPKIIEHLREKGYLVKAGEI 397
E DFE Y +P I V P+ + H +E+
Sbjct: 342 ACDERDFEFANLYHIP------------------IKVITQSPQNLPHTKEE--------- 374
Query: 398 EHKYPHCWRCKTPLIFRATDQWF-LKISKVKDKII----KENDEKVTWYPDWVKIRFDNG 452
I + + +W L S ++KII KEN K + R
Sbjct: 375 --------------ILKNSGEWSDLSSSVAREKIIAYFEKENLGKRV-----INYRLQ-- 413
Query: 453 VRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEE 512
DW +SRQRYWG P+P+ + I +LP + E
Sbjct: 414 -----DWGVSRQRYWGAPIPMIHCKHCGIV-------------------PETQLPVTLPE 449
Query: 513 KLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGY--PRNK 570
+ VI+ + P + H + A K + KD R D +D + S SW L Y P+N+
Sbjct: 450 DI-VIDGEGNPLEKHASWKFAQCPKCH-KDALRETDTMDTFIQS---SWYFLRYTTPKNQ 504
Query: 571 ---ELFEK-----LWPADFIVEG-EDQVTKWFYSQ------QAASIVAFDTVPYRRVAMH 615
+ F++ P D + G E + Y++ + + D P++++
Sbjct: 505 RENQAFDQNYLKYFMPVDTYIGGIEHAILHLLYARFFTKALRDLGYLHLDE-PFKQLITQ 563
Query: 616 GYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENLKFSWKGVEQVRRM 675
G VL + G KMSKS GN++ P+E++++ G D R ++L+A P + L+++ +E R
Sbjct: 564 GMVLKD-GAKMSKSKGNVVSPKEILKKYGADAVRLFILFAAPPAKELEWNDNALEGAHRF 622
Query: 676 LNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISEVENGIESFYLT 735
+ L++ + S F LN + R++ L + + E+ N ES Y
Sbjct: 623 IKRLYDKANAITPTTSKPEFKEVGLNEAQKLARKKVYEALKKSH----EIFNKAESAY-- 676
Query: 736 KATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFDVLLRLLAPFTPYI 795
A L +E L+ L + ++ Y+ VLL++L P P+
Sbjct: 677 -AFNTLIASCMEALN---------ALNAQSDEQILCEGYF-------VLLQILEPMIPHT 719
Query: 796 AEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREMEFIRRIVEAGSAARQRAKIKL 855
A E+ + L + N + + +VDE A+ E +F+ + R K+ +
Sbjct: 720 AWELSERLFKR-ENFKPI------EVDESALIE------DFMTLGLTINGKRRAELKVNI 766
Query: 856 RYPVRRIIIETEDETVK 872
III + E K
Sbjct: 767 NASKEEIIILAKKELEK 783
>dbj|BAB15191.1| (AK025618) unnamed protein product [Homo sapiens]
Length = 642
Score = 130 bits (323), Expect = 1e-28
Identities = 130/548 (23%), Positives = 217/548 (38%), Gaps = 85/548 (15%)
Query: 367 GKW-KGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISK 425
G W +G++ A KI+ L E+G P C R + + +QWF++ +
Sbjct: 6 GDWLQGLHRFVAREKIMSVLSERGLFRGLQNHPMVLPICSRSGDVIEYLLKNQWFVRCQE 65
Query: 426 VKDKIIKENDE-KVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVV 484
+ + K + + P + + + + GDW +SRQ +WG +P +
Sbjct: 66 MGARAAKAVESGALELSPSFHQKNWQHWFSHIGDWCVSRQLWWGHQIPAY---------- 115
Query: 485 GSWRELVELAVAIEVNGERI--ELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKD 542
L V GE + S E +V E G RP +
Sbjct: 116 --------LVVEDHAQGEEDCWVVGRSEAEAREVAAELTG-----RPGAEL--------T 154
Query: 543 MRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIV 602
+ R DV+D WF S + +++LG+P+ + +P + G D + W
Sbjct: 155 LERDPDVLDTWFSSALFPFSALGWPQETPDLARFYPLSLLETGSDLLLFWVGRMVMLGTQ 214
Query: 603 AFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVE--------------------- 641
+P+ +V +H V D +G KMSKSLGN++ P +++
Sbjct: 215 LTGQLPFSKVLLHPMVRDRQGRKMSKSLGNVLDPRDIISGVEMQLLQEKLRSGNLDPAEL 274
Query: 642 ----------------RAGRDTFRFYMLWATNPWENLKFSWKGVEQVRRMLNILWNVYVL 685
G D RF + +L S V+ R N +WN
Sbjct: 275 AIVAAAQKKDFPHGIPECGTDALRFTLCSHGVQAGDLHLSVSEVQSCRHFCNKIWNALRF 334
Query: 686 ASTYMSLDNFDPRKLNPDEL-PFREEDKWILSRVNSLISEVENGIESFYLTKATRALYNF 744
+ + F P+ +EL P D WILSR+ E E G + L+ T AL++F
Sbjct: 335 ILNALG-EKFVPQPA--EELSPSSPMDAWILSRLALAAQECERGFLTRELSLVTHALHHF 391
Query: 745 VVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNL- 803
+ +L Y+ ++ LW P L L+ D+ LRLLAP P++AEE++Q L
Sbjct: 392 WLHNLCDVYLEAVKPVLW---HSPRPLGPPQVLFSCADLGLRLLAPLMPFLAEELWQRLP 448
Query: 804 IRP-FTNVESVHMLDWPKVD--EKAIDEELEREMEFIRRIVEAGSAARQRAKIKLRYPVR 860
RP S+ + +P E ELER ++ +V+ A R ++ P
Sbjct: 449 PRPGCPPAPSISVAPYPSACSLEHWRQPELERRFSRVQEVVQVLRALRATYQLTKARP-- 506
Query: 861 RIIIETED 868
R+++++ +
Sbjct: 507 RVLLQSSE 514
>gb|AAK40823.1| Leucyl-tRNA synthetase (leuS-1) [Sulfolobus solfataricus]
Length = 934
Score = 129 bits (322), Expect = 1e-28
Identities = 192/923 (20%), Positives = 368/923 (39%), Gaps = 145/923 (15%)
Query: 23 WSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRTMQGYNVWR 82
W +++++ + K PK++ PY + +H+G I D+ R+ M+GYNV
Sbjct: 17 WEKSKVFETNMDYSK--PKFFITVPFPYTNSPMHVGHGRTYITADIYARYLRMKGYNVLF 74
Query: 83 QPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIMTEQFKM--- 139
+ G P+ + ++ V F K E + +K + + +K+
Sbjct: 75 PFAFQFTGTPVLAIADSIR--------RGEVDVIEFFKNVYEVPQDKIKELEDPYKLAEY 126
Query: 140 -----------LGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCE 188
+G+ +DW + T + + + L + E G L + V+ +CP
Sbjct: 127 FKEEMKNTAKSIGMSIDWRRTFTTTDPRFEKFIHWQLGKLKELGYLVTEDDVVGYCPNDG 186
Query: 189 TALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVK 248
+ H+ RG+ + + F EG ++ ++ T+ P + +A+ + D +YV
Sbjct: 187 FPVGMHDTRGDIEPEITTMNVIMF--EGSDSYNFMVATSRPELIFGVVALMVNHDANYVV 244
Query: 249 VKVEFNGREEYWILAKA-----------LVDKVLGEIGVKGEVVEEFKGRELEGLRYVHI 297
V E+ G+ + I KA LV + VK + GR+LE ++ ++
Sbjct: 245 V--EYEGKN-FIISEKAYKKLSFQKNMKLVKTITTSDIVKLYAINPITGRKLEIIKNKYV 301
Query: 298 -------LMDEYPRQKEF--------KEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEE 342
++ YP F +++E V + + + ++ T + +
Sbjct: 302 DPSLGTGVVMSYPAHDPFHYLAMTETNKEFEVIPVVETEELDEIPGESAVLQTKNPYALK 361
Query: 343 DF-------EVGQKYGLPVYSPL--DDQGKYTEGKWKGIYVKEADPKIIEHLREKGYLVK 393
DF E + Y + L D +Y + G V+EA IE L+
Sbjct: 362 DFMESIYKTEYYKGYMKDIILSLVPDFLKQYVKENIVGKQVQEARKNTIELLKSLNIYDT 421
Query: 394 AGEIEHKYPHCWRCKTPLI-FRATDQWFLKISKVKDKIIK-ENDEKVTWYPDWVKIRFDN 451
EI + +C RC + ++ R DQWF+ K K + + P+ K +
Sbjct: 422 IYEISNGPIYC-RCGSEIVPKRIKDQWFIAYDNPKWKASALKAINNIELIPNPTKTELEK 480
Query: 452 GVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYE 511
V ++ I R R G+ LP +S+ E + L+ + ++P + E
Sbjct: 481 IVFNARKEPIGRSRGIGVKLPWDESQIVESLSDSTLYTLLYTVI--------YKMPINIE 532
Query: 512 EKLK--VIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRN 569
+++ + K ++L R Y G D+ ++++ W+
Sbjct: 533 KEIFDFIFLGKGDAKELERKY---------GTDLIQLREEFLYWY--------------- 568
Query: 570 KELFEKLWPADFIVEGEDQVTKW--FYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMS 627
P D G D + FY +I +P +R+ ++G+V G KMS
Sbjct: 569 --------PVDQRHTGRDLIQNHIPFYIYNHLAIFGEKYLP-KRIVINGFVR-VGGRKMS 618
Query: 628 KSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENLKFSWKGVEQVRRMLNILWNVYVLAS 687
KSL NI + ++ G D R + ++ ++L F+ V + L +Y L
Sbjct: 619 KSLRNIYTLSKAIKEFGVDPVRIALTSTSDLLQDLDFNENLVNPIAEQLK---KIYDLID 675
Query: 688 TYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVE 747
+S+ N + R D+WI S+V +I +V N I SF A L + +
Sbjct: 676 RLLSI--------NTEIKELRTADEWISSKVRDIIEKVNNNITSFKYRDAVNLLL-YEIY 726
Query: 748 DLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPF 807
++ R Y L+ E P++ + K+ + +R LAPF P+IAEE++ + F
Sbjct: 727 EILRDYFDLV--------EIPNQ----EVIRKILSIWIRALAPFVPHIAEELWHKISSTF 774
Query: 808 TNVESVHMLDWPKVDEKAIDEELEREMEFIRRIVEAGSAARQRAKIKLRYPVRRIIIETE 867
++E +P+ +E + + E+ +I +I+E R+ I + + II E
Sbjct: 775 VSLEK-----YPEPNELNLYPDAILEISYINKIIE---NVRELEDIVHKKAEKVIIYINE 826
Query: 868 DETVKKAVERLNRILRDQLNAKE 890
E VK+ ++ + + +++ +E
Sbjct: 827 SEKVKELMKNAIKAVNEEIPLRE 849
>sp|P43827|SYL_HAEIN LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS)
>gi|1074962|pir||H64102 leucine--tRNA ligase (EC
6.1.1.4) - Haemophilus influenzae (strain Rd KW20)
>gi|1573943|gb|AAC22581.1| (U32774) leucyl-tRNA
synthetase (leuS) [Haemophilus influenzae Rd]
Length = 861
Score = 125 bits (312), Expect = 2e-27
Identities = 135/512 (26%), Positives = 206/512 (39%), Gaps = 112/512 (21%)
Query: 9 EYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDM 68
+Y P +E KV+++W+EN++++ +K+ K+ KYY L PY SG +H+G N I D+
Sbjct: 4 QYRPDMIEPKVQQYWAENKVFKAIKDESKE--KYYCLSMFPYPSGRLHMGHVRNYTIGDV 61
Query: 69 IIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALN 128
I R++ M G NV + G+D GLP E ++N K +
Sbjct: 62 ISRYQRMLGKNVLQPFGWDAFGLPAE-----------------GAAIKNKTAPAK-WTYE 103
Query: 129 NLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCE 188
N+ M +Q ++LG DWD T K EY + + ++KGL+ K ++WCP E
Sbjct: 104 NIAYMKKQLQLLGFGFDWDREIATCKPEYYKWEQWFFTELYKKGLVYKKTSTVNWCPNDE 163
Query: 189 TALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDY-DYV 247
T LA +V R D PVE KE I T + + P + D V
Sbjct: 164 TVLANEQVHEGCCWRCDT------PVEQKEIPQWFI-KITDYAEQLLGGLDTLPQWPDMV 216
Query: 248 K-VKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQK 306
K ++ + GR E + V ++ V + F G G+ H L +
Sbjct: 217 KTMQRNWIGRSE-GVEITFDVANTNEKVAVYTTRPDTFYGVSYLGIAAAHPLASLAAQNN 275
Query: 307 E----FKEKYEWAHRVILADFVTLEE---GTGL--------------------------- 332
F ++ + A +V AD T+E+ TGL
Sbjct: 276 SELAAFIQEAKNA-KVAEADLATMEKKGMATGLFAIHPLTGDKLPIWVANFVLMHYGTGA 334
Query: 333 VHTAPGHGEEDFEVGQKYGLP---VYSPLDDQGKYTEGKWKGIYVKEADPKIIEHLREKG 389
V P H + DFE QKY LP V +PL D+ + +EH G
Sbjct: 335 VMAVPAHDQRDFEFAQKYSLPIKQVIAPLADE-----------EIDLTKQAFVEH----G 379
Query: 390 YLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKDKIIKENDEKVTWYPDWVKIRF 449
LV + E + K + + + DK+ EK+ V R
Sbjct: 380 KLVNSDEFDGK-----------------NFDGAFNGIADKL-----EKLGVGKRQVNYRL 417
Query: 450 DNGVRDSGDWVISRQRYWGIPLPIWQSEDGEI 481
DW +SRQRYWG P+P+ E+G++
Sbjct: 418 -------RDWGVSRQRYWGAPIPMLTLENGDV 442
Score = 74.9 bits (181), Expect = 4e-12
Identities = 67/255 (26%), Positives = 114/255 (44%), Gaps = 36/255 (14%)
Query: 625 KMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENLKFSWKGVEQVRRMLNILWNVYV 684
KMSKS N I P+E+VE+ G DT R +M++A+ L++ GVE +R L +WN+
Sbjct: 619 KMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAEMTLEWQESGVEGAKRFLGRVWNL-- 676
Query: 685 LASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISEVENGIESFYLTKATRALYNF 744
Y N P K + D E K + V+ I++V + I R +N
Sbjct: 677 ---VYQYQQN--PAKTSLDLTALSAEQKVLRREVHKTIAKVSDDI-------GRRQTFNT 724
Query: 745 VVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLI 804
+ + +L + L E +D +A + ++R+L P TP+I E++Q L
Sbjct: 725 AIAAVMELMNKLTKASLDSE-QDRAVMA------EALSAVVRMLYPITPHICFELWQAL- 776
Query: 805 RPFTNVESVHMLDWPKVDEKAIDEELEREMEFIRRIVEAGSAARQRAKIKLRYPVRRIII 864
N ++ +W K DE A+ E+ +++ + R K+ + +
Sbjct: 777 ---GNESAIDTAEWVKADEAAMVED--------EKLIVVQVNGKVRGKVTVATDADEDTV 825
Query: 865 ET---EDETVKKAVE 876
+T DE VKK ++
Sbjct: 826 KTIAFADENVKKFID 840
>pir||T01968 isoleucine--tRNA ligase homolog T9A4.4 - Arabidopsis thaliana
>gi|3695406|gb|AAC62806.1| (AF096373) similar to
isoleucyl-tRNA synthetases [Arabidopsis thaliana]
Length = 485
Score = 123 bits (305), Expect = 1e-26
Identities = 125/473 (26%), Positives = 208/473 (43%), Gaps = 48/473 (10%)
Query: 600 SIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPW 659
S F+ ++ + +G VL E G KM+K L N P EV++ G +F + ML +
Sbjct: 4 STALFEKPAFKNLICNGLVLAEDGKKMAKKLRNYPPPLEVIDEYGAVSFPYNMLLCCDAV 63
Query: 660 ------------ENLKFSWKGVEQVRRMLNILW-NVY-VLASTYMSLDNFDPRKLNPDEL 705
E L+F +GV V + + + W N Y L L+ P +L
Sbjct: 64 RLYLINSPVVRAEPLRFKKEGVLGVVKDVFLPWYNAYRFLVQNAKRLETEGGVPFVPTDL 123
Query: 706 PFREE----DKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRL 761
+ D+WI S SL+ V ++++ L L F+ ++L+ YVR RKRL
Sbjct: 124 ATIQSANILDQWIHSATQSLVRFVREEMDAYRLYTVVPRLLKFL-DNLTNIYVRFNRKRL 182
Query: 762 WVEGEDPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFT-NVESVHMLDWPK 820
+ D A TL+ V +++APFTP+ E +YQNL + + ESVH P
Sbjct: 183 KGRTGEDDCHTALSTLFNVLLTSCKVMAPFTPFFTETLYQNLRKACKGSEESVHYCSIPP 242
Query: 821 VDEKAIDEELEREMEFIRRIVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNR 880
E E +E + + +I++ R+R K+ L+ P++ +I+ D + +
Sbjct: 243 -REGMEGERIELSVTRMMKIIDLARNIRERNKLPLKTPLKEMIVVHPDADF---LNDITG 298
Query: 881 ILRDQLNAKE-VKVGRVERELTIK--PNFAKLGPEFKGDAKIIAKWINENGRE----LYE 933
+ ++LN + V + ++K P+F+ LG ++AK + E ++ E
Sbjct: 299 YVLEELNVRSLVPCNDTLKYASLKAEPDFSVLGKRLGKSMGLVAKEVKEMSQKDILAFEE 358
Query: 934 KGELTV------EIDGKTFHL------TREHIIVEEKLPDFFVSEEFEGG-----RVFVD 976
GE+T+ E D K H I+ K PD E + V +D
Sbjct: 359 AGEVTIANHLLKETDIKVSHAMMFSCEIALRIVRVFKRPDDLKENEIDSAGDGDVLVILD 418
Query: 977 KTLTRELIAEGLAREFVRRIQEMRKRLDLDVNDRIIVTIETTDENVELLKENL 1029
L+ G ARE V RIQ++RK+ L+ D + V ++ DE+ + K+ L
Sbjct: 419 LRADDSLVEAGFAREIVNRIQKLRKKSGLEPTDFVEVYFQSLDEDESVSKQVL 471
>pir||E82590 leucyl-tRNA synthetase XF2176 [imported] - Xylella fastidiosa
(strain 9a5c) >gi|9107316|gb|AAF84975.1|AE004031_7
(AE004031) leucyl-tRNA synthetase [Xylella fastidiosa]
Length = 887
Score = 119 bits (295), Expect = 2e-25
Identities = 126/530 (23%), Positives = 197/530 (36%), Gaps = 144/530 (27%)
Query: 6 EFREYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKII 65
E YDP+++E + +W + + K PKYY L PY SGA+H+G N I
Sbjct: 12 EANTYDPQRIESTAQHYWDSTHAFEVNEHSNK--PKYYCLSMLPYPSGALHMGHVRNYTI 69
Query: 66 KDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEF 125
D+I R++ M G+NV + G+D GLP E I+ K+ + K
Sbjct: 70 GDVISRYKRMTGHNVLQPMGWDAFGLPAE-----------NAAIKNKVAPAQWTYK---- 114
Query: 126 ALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCP 185
N++ M Q K LG +DW + T + +Y R KGL + +++W P
Sbjct: 115 ---NIERMRTQLKSLGYAIDWSREFATCQPDYYVHEQHMFTRLMRKGLAYRRNALVNWDP 171
Query: 186 RCETALAEHEV---RG-------------EYKLR-------------------------- 203
+T LA +V RG ++ LR
Sbjct: 172 VDQTVLANEQVIDGRGWRSGAPVEKREIPQWFLRITDYAQELLDGLNTLDDWPEPVKTMQ 231
Query: 204 -----KDPSIYVKFPVEGKEN---EYLLIWTTTPWTLPANLAVSAHPDYDYVKVKVEFNG 255
+ + ++F V +N E L ++TT P TL VS ++ + N
Sbjct: 232 RNWIGRSEGLEIQFEVRDADNNALEALRVFTTRPDTLLGVTFVSIAAEHPLALHAAKSNP 291
Query: 256 REEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFKEKYEWA 315
LA L + G + +E +G + GL+ +H + +E
Sbjct: 292 -----ALAGLLTEMKQGGLSEAELKTQEKRGMD-TGLKAIHPITNE-------------Q 332
Query: 316 HRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYS--PLDDQGKYTEGKWKGIY 373
V +A+FV + GTG V PGH + D E KYGLP+ L + E W+
Sbjct: 333 LPVWVANFVLMAYGTGAVMAVPGHDQRDQEFANKYGLPIRQVIALKEPKNQDESTWE--- 389
Query: 374 VKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKDKIIKE 433
P WR W+ ++ + ++I
Sbjct: 390 ----------------------------PDVWR-----------DWYADKTR-EFELINS 409
Query: 434 NDEKVTWYPDWVKI---RFDNGVRDS-------GDWVISRQRYWGIPLPI 473
+ Y D ++ RF+ R DW +SRQRYWG P+P+
Sbjct: 410 AEFDGLDYQDAFEVLAERFERQGRGQRRVNYRLRDWGVSRQRYWGCPIPV 459
>sp|O84211|SYL_CHLTR LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS)
>gi|7437540|pir||C71544 leucine--tRNA ligase (EC
6.1.1.4) - Chlamydia trachomatis (serotype D, strain
UW3/Cx) >gi|3328616|gb|AAC67801.1| (AE001294) Leucyl
tRNA Synthetase [Chlamydia trachomatis]
Length = 819
Score = 118 bits (294), Expect = 2e-25
Identities = 205/933 (21%), Positives = 329/933 (34%), Gaps = 246/933 (26%)
Query: 10 YDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGA-IHLGTAWNKIIKDM 68
YDP +EEK +KFW ++++ ++ K KYY LD PY SGA +H+G D+
Sbjct: 3 YDPGLIEEKWQKFWENEQVFKAEEDETKT--KYYVLDMFPYPSGAGLHVGHLIGYTATDI 60
Query: 69 IIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALN 128
+ R++ QG++V G+D GLP E + A+ T + + NF K
Sbjct: 61 VARYKRAQGFSVLHPMGWDSFGLPAE---QYAIRTGTHPRETTEKNIANFKK-------- 109
Query: 129 NLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCE 188
Q +G D + T EY + +EKGL +++CP
Sbjct: 110 -------QLTAMGFSYDESREFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELG 162
Query: 189 TALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVK 248
T L+ E+ + S+ +PV E L W L ++A D ++
Sbjct: 163 TVLSNEEIENGF------SVDGGYPV---ERRMLRQWV---------LRITAFAD-QLLE 203
Query: 249 VKVEFNGREEYWILAKALVDKVLG---EIGVKGEVVEEFKGR--ELEGLRYV-----HIL 298
E + E L K + K G + V+E F R L G+ ++ H L
Sbjct: 204 GLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIEVFTTRPDTLIGVSFLALAPEHPL 263
Query: 299 MD------------EYPRQKEFKE--------------------KYEWAHRVI---LADF 323
+D +Y ++ + K K+ H++I +AD+
Sbjct: 264 VDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKSGVFTGSYAKHPVTHKLIPIWIADY 323
Query: 324 VTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTEGKWKGIYVKEADPKIIE 383
V + G+G V P H E D +++ LPV S L+ +G +G ++ +
Sbjct: 324 VLIGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLNKEGVCINSCCEGFHLDGLSGE--- 380
Query: 384 HLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKDKIIKENDEKVTWYPD 443
K Y++ E H L +K+ K+ D
Sbjct: 381 --EAKQYVINFLEENH---------------------LGAAKIAYKL-----------RD 406
Query: 444 WVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVELAVAIEVNGER 503
W + SRQRYWG P+PI ED GS R L + + + +
Sbjct: 407 W---------------LFSRQRYWGEPIPIIHFED------GSCRPLRDYELPLLPPEIQ 445
Query: 504 IELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVV----DVWFDSGIA 559
PE + GP R +V F + R + W+
Sbjct: 446 DYRPEGVGQ---------GPLAKVREWVQVFDTETQRAGKRETHTMPQWAGSCWYYLRFC 496
Query: 560 SWASLGYPRNKELFEKLWPADFIVEGEDQVTK-------WFYSQQAASIVAFDTVPYRRV 612
+ P KE + P D + G + W A IV+ P++++
Sbjct: 497 DAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYARFWHQVFYEAGIVS-TPEPFKKL 555
Query: 613 AMHGYV--------------------------------LDEKGDKMSKSLGNIIRPEEVV 640
G V LD + +KMSKS N + P+ ++
Sbjct: 556 VNQGLVLATSYRIPGKGYIYPEIAKEENGKWVAPSGEELDVRQEKMSKSKLNGVDPQILI 615
Query: 641 ERAGRDTFRFYMLWATNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKL 700
+ G D R Y +++ +N +S +GV RR LN + + V + +NF+
Sbjct: 616 DEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLNRFYEM-VSSDRVKEDNNFEG--- 671
Query: 701 NPDELPFREEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKR 760
LS + L+ V + IE L + F+
Sbjct: 672 --------------LSLAHKLVQRVTDAIEKLSLNTIPSSFMEFI--------------- 702
Query: 761 LWVEGEDPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPK 820
D KLA Y ++ +R LAP P+I+EE++ L N V WP
Sbjct: 703 -----NDFVKLAVYPK--SAVEMAVRALAPIAPHISEELWVLL----GNSPGVQKSGWPS 751
Query: 821 VDEKAIDEELEREMEFIRRIVEAGSAARQRAKI 853
V + E LE + I +V+ R R I
Sbjct: 752 V----LPEYLEGQTVTI--VVQVNGKLRARLDI 778
>sp|Q9Z930|SYL_CHLPN LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS)
>gi|7437542|pir||C72113 leucine--tRNA ligase (EC
6.1.1.4) [similarity] - Chlamydophila pneumoniae
(strains CWL029 and AR39) >gi|4376420|gb|AAD18306.1|
(AE001602) Leucyl tRNA Synthetase [Chlamydophila
pneumoniae CWL029] >gi|7189530|gb|AAF38433.1| (AE002219)
leucyl-tRNA synthetase [Chlamydophila pneumoniae AR39]
>gi|8978526|dbj|BAA98363.1| (AP002545) leucyl tRNA
synthetase [Chlamydophila pneumoniae J138]
Length = 820
Score = 115 bits (286), Expect = 2e-24
Identities = 197/937 (21%), Positives = 335/937 (35%), Gaps = 233/937 (24%)
Query: 10 YDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGA-IHLGTAWNKIIKDM 68
YDP +E+K ++FW E+ ++ ++ +D KYY LD PY SGA +H+G D+
Sbjct: 3 YDPNLIEKKWQQFWKEHRSFQANED--EDKVKYYVLDMFPYPSGAGLHVGHLIGYTATDI 60
Query: 69 IIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALN 128
+ R++ +G++V G+D GLP E + A+ T ++ + + NF K
Sbjct: 61 VARYKRARGFSVLHPMGWDSFGLPAE---QYAIRTGTHPKVTTQKNIANFKK-------- 109
Query: 129 NLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCE 188
Q +G D + T +Y +++GL +++CP
Sbjct: 110 -------QLSAMGFSYDEGREFATSDPDYYHWTQKLFLFLYDQGLAYMADMAVNYCPELG 162
Query: 189 TALAEHEVRGEYKLRKDPSIYVKFPVEGKE-NEYLLIWTTTPWTLPANLAVSAHPDYDYV 247
T L+ EV + SI +PVE K +++L T L L P+ +
Sbjct: 163 TVLSNEEVENGF------SIEGGYPVERKMLRQWILKITAYADKLLEGLDALDWPE-NVK 215
Query: 248 KVKVEFNGREEYWILAKAL------------VDKVLG--------EIGVKGEVVEEFKGR 287
+++ + G+ E ++ L +D +LG E +V E +
Sbjct: 216 QLQKNWIGKSEGALVTFHLTQEGSLEAFTTRLDTLLGVSFLVIAPEHPDLDSIVSEEQRD 275
Query: 288 ELEGLRYVHILMDEYPRQKEFKEKY-----EWAHRVI--------LADFVTLEEGTGLVH 334
E+ + E R K K +A I ++D+V L GTG+V
Sbjct: 276 EVTAYVQESLRKSERDRISSVKTKTGVFTGNYAKHPITGNLLPVWISDYVVLGYGTGVVM 335
Query: 335 TAPGHGEEDFEVGQKYGLPVYSPLDDQG-----KYTEGKWKGIYVKEADPKIIEHLREKG 389
P H E D E + + LP++ +DD G Y + G+ +EA +I +L +
Sbjct: 336 GVPAHDERDREFAEMFSLPIHEVIDDNGVCIHSNYNDFCLNGLSGQEAKDYVINYLEMRS 395
Query: 390 YLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKDKIIKENDEKVTWYPDWVKIRF 449
R KT R DW
Sbjct: 396 --------------LGRAKTMYRLR----------------------------DW----- 408
Query: 450 DNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVELAVAIEVNGERIELPES 509
+ SRQRYWG P+PI ED G+ R L + + + PE
Sbjct: 409 ----------LFSRQRYWGEPIPIIHFED------GTHRPLEDDELPLLPPNIDDYRPEG 452
Query: 510 YEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVV----DVWFDSGIASWASLG 565
+ + GP + +V + K R + W+ +
Sbjct: 453 FGQ---------GPLAKAQDWVHIYDEKTGRPGCRETYTMPQWAGSCWYYLRFCDAHNSQ 503
Query: 566 YPRNKELFEKLWPADFIVEG-EDQVTKWFYSQ------QAASIVAFDTVPYRRVAMHGYV 618
P +KE P D + G E V YS+ A +V+ P++++ G V
Sbjct: 504 LPWSKEKESYWMPVDLYIGGAEHAVLHLLYSRFWHRVFYDAGLVS-TPEPFKKLINQGLV 562
Query: 619 L------------------DEKG--------------DKMSKSLGNIIRPEEVVERAGRD 646
L +E G +KMSKS N + P+ ++E G D
Sbjct: 563 LASSYRIPGKGYVSIEDVREENGTWISTCGEIVEVRQEKMSKSKLNGVDPQVLIEEYGAD 622
Query: 647 TFRFYMLWATNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELP 706
R Y +++ +N +S +GV RR LN +++ V +S +
Sbjct: 623 ALRMYAMFSGPLDKNKTWSNEGVGGCRRFLNRFYDL-VTSSEVQDI-------------- 667
Query: 707 FREEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGE 766
ED+ L + L+ + IE L + F+
Sbjct: 668 ---EDRDGLVLAHKLVFRITEHIEKMSLNTIPSSFMEFL--------------------N 704
Query: 767 DPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAI 826
D KL Y + + +R+L P P+I+EE++ L P + WP++DE +
Sbjct: 705 DFSKLPVYSK--RALSMAVRVLEPIAPHISEELWVILGNP----PGIDQAAWPQIDESYL 758
Query: 827 DEELEREMEFIRRIVEAGSAARQRAKIKLRYPVRRII 863
+ + +V+ R R ++ P ++
Sbjct: 759 ------VAQTVTFVVQVNGKLRGRLEVAKEAPKEEVL 789
>pir||A41882 leucine--tRNA ligase (EC 6.1.1.4) - Bacillus subtilis
>gi|143148|gb|AAA22571.1| (M88581) transfer RNA-Leu
synthetase [Bacillus subtilis]
Length = 804
Score = 109 bits (270), Expect = 2e-22
Identities = 139/586 (23%), Positives = 232/586 (38%), Gaps = 145/586 (24%)
Query: 320 LADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLD----DQGKYT-EGKW----- 369
+AD+V GTG V PGH E DFE + +GLPV + ++ YT +G+
Sbjct: 322 IADYVLASYGTGAVMAVPGHDERDFEFAKTFGLPVKEVVKGGNVEEAAYTGDGEHVNSDF 381
Query: 370 -KGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKD 428
G++ +EA K+I L E
Sbjct: 382 LNGLHKQEAIEKVIAWLEET---------------------------------------- 401
Query: 429 KIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWR 488
K ++KVT+ ++R DW+ SRQRYWG P+P+ EDG V
Sbjct: 402 ---KNGEKKVTY-----RLR---------DWLFSRQRYWGEPIPVIHWEDGTSTAVPE-- 442
Query: 489 ELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKD 548
EL + + E I+ + E L I+E + D GK RR +
Sbjct: 443 --EELPLILPKTDE-IKPSGTGESPLANIKEWVEVTDPE-----------TGKKGRRETN 488
Query: 549 VVDVWFDSGIASWASLGY--PRNK------ELFEKLWPADFIVEGEDQVTKW-----FYS 595
+ W S W L Y P N E EK P D + G + F+
Sbjct: 489 TMPQWAGS---CWYFLRYIDPHNPDQLASPEKLEKWLPVDMYIGGAEHAVLHLLYARFWH 545
Query: 596 QQAASIVAFDTV-PYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLW 654
+ I T P++++ G +L E +KMSKS GN++ P+E+V G DT R Y ++
Sbjct: 546 KFLYDIGVVPTKEPFQKLYNQGMILGENNEKMSKSKGNVVNPDEIVASHGADTLRLYEMF 605
Query: 655 ATNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWI 714
++ +S G++ RR L+ +W +++ D +LN + E
Sbjct: 606 MGPLDASIAWSESGLDGARRFLDRVWRLFI----------EDSGELNGKIVEGAGE---T 652
Query: 715 LSRV-NSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAA 773
L RV + + +V + E L F+ E Y + ++EG
Sbjct: 653 LERVYHETVMKVTDHYEGLRFNTGISQLMVFINEA----YKATELPKEYMEG-------- 700
Query: 774 YYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDE-KAIDEELER 832
++LL+P P++AEE+++ L T + WP DE K +D+E+E
Sbjct: 701 ----------FVKLLSPVAPHLAEELWEKLGHSGT----IAYEAWPVYDETKLVDDEVEI 746
Query: 833 EMEF---IRRIVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAV 875
++ ++ ++ + A + +L ++ + E +T++K +
Sbjct: 747 VVQLNGKVKAKLQVPADATKEQLEQLAQADEKVKEQLEGKTIRKII 792
Score = 89.3 bits (218), Expect = 2e-16
Identities = 58/188 (30%), Positives = 88/188 (45%), Gaps = 21/188 (11%)
Query: 10 YDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGA-IHLGTAWNKIIKDM 68
+ K++E+K + +W EN+ + + K K+Y LD PY SGA +H+G D+
Sbjct: 3 FQHKEIEKKWQTYWLENKTFATLDNNEKQ--KFYALDMFPYPSGAGLHVGHPEGYTATDI 60
Query: 69 IIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALN 128
+ R + MQGY+V G+D GLP E + AL + K ++NF +
Sbjct: 61 LSRMKRMQGYDVLHPMGWDAFGLPAE---QYALDTGNDPAVFTKQNIDNFRR-------- 109
Query: 129 NLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCE 188
Q + LG DWD T EY + + + +EKGL D+ ++WCP
Sbjct: 110 -------QIQALGFSYDWDREINTTDPEYYKWTQWIFLKLYEKGLAYVDEVPVNWCPALG 162
Query: 189 TALAEHEV 196
T LA EV
Sbjct: 163 TVLANEEV 170
>pir||F82899 leucyl-tRNA synthetase UU371 [imported] - Ureaplasma urealyticum
>gi|6899353|gb|AAF30780.1|AE002134_4 (AE002134)
leucyl-tRNA synthetase [Ureaplasma urealyticum]
Length = 806
Score = 103 bits (254), Expect = 1e-20
Identities = 126/588 (21%), Positives = 233/588 (39%), Gaps = 136/588 (23%)
Query: 320 LADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTEGKWKGIYVKEADP 379
++D+V + TG V P H E D+ +KY LP+ S +D + K G+++ A
Sbjct: 326 VSDYVLMNFATGAVMGVPAHDERDYAFAKKYALPIKSVIDTKQKLPYAG-DGLHINSA-- 382
Query: 380 KIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKDKIIKEN-DEKV 438
G +K + + + D +IK + +KV
Sbjct: 383 ------MINGLNIKQSQ---------------------------NVLNDYLIKNHLGKKV 409
Query: 439 TWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVELAVAIE 498
Y K+R +W+ SRQRYWG P P+ E+ +I +++E +
Sbjct: 410 ANY----KLR---------NWIFSRQRYWGEPFPVLFDENNQI-------KIIEDLPVLL 449
Query: 499 VNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGI 558
N + ++ E L +E L ++++GK RR + + W S
Sbjct: 450 PNLNEFKPSKTGESPLANAQEWL-------------YVEIDGKKYRRETNTMPQWAGS-- 494
Query: 559 ASWASLGY----------PRN----KELFEKLWPADFIVEGEDQVT-----KWFYSQQAA 599
SW L Y P N K+ F K P D + G++ F+ +
Sbjct: 495 -SWYFLAYILKNEDGSYTPLNSEEAKKRFAKWLPVDVYIGGQEHAVLHLLYSRFWHRFLY 553
Query: 600 SIVAFDTV-PYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNP 658
I T P+ +V G +L E +KMSKS GN+I P++++ G DT R Y ++
Sbjct: 554 DIGVVPTKEPFYKVINQGMILGENNEKMSKSKGNVINPDDIIASHGADTLRIYEMFMGPL 613
Query: 659 WENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRV 718
+L ++ G++ +R+ L+ ++ +Y N EL E+ L+++
Sbjct: 614 TASLPWNPDGLDAMRKWLDRVYRLY----------------HNLSELEVVED----LNKL 653
Query: 719 NSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLW 778
N I + + Y +N + ++ +V ++ K + +
Sbjct: 654 NEEIIIAYHTLIKNYTKAINEQAFNIAISEM-MVFVNVLYKNKVIN-------------Y 699
Query: 779 KVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDE-KAIDEELEREMEF- 836
++ D L LL+ + P++AEE+Y + ESV + P DE K I + + ++
Sbjct: 700 ELLDNFLILLSCYAPHLAEELYS-----LNHSESVCLQKMPIYDEQKIIAQNITIPIQIN 754
Query: 837 --IRRIVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRIL 882
++ + + L ++ E D+ +KK + +N+I+
Sbjct: 755 GKLKHTINVLRDTNAEELVNLALACEQVKQEIGDQPIKKQIVVVNKII 802
Score = 76.1 bits (184), Expect = 2e-12
Identities = 51/188 (27%), Positives = 85/188 (45%), Gaps = 20/188 (10%)
Query: 10 YDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSG-AIHLGTAWNKIIKDM 68
Y+ K+E+K +K+W +N+ ++ V + K+Y LD PY SG +H+G D+
Sbjct: 2 YNHNKIEKKWQKYWLDNKTFKFVDN-PNNPKKFYVLDMFPYPSGKGLHVGHPKGYTATDV 60
Query: 69 IIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALN 128
I RF+ + GY+V G+D GLP E L+T F
Sbjct: 61 ISRFKRLNGYDVLHPIGWDAFGLPAE-----QYALETNNHPHT-------------FTQQ 102
Query: 129 NLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCE 188
N+KI +Q +M+G D+D T ++ + + + ++ L E ++WC
Sbjct: 103 NIKIFRKQLQMIGFDFDYDKEVDTTDPQFYQWTQWIFVQLYKHNLAEIQDIDVNWCENLG 162
Query: 189 TALAEHEV 196
T L+ EV
Sbjct: 163 TVLSNEEV 170
>sp|Q9Z987|SYV_CHLPN VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|7437658|pir||B72120 valine--tRNA ligase (EC 6.1.1.9)
[similarity] - Chlamydophila pneumoniae (strains CWL029
and AR39) >gi|4376354|gb|AAD18247.1| (AE001595) Valyl
tRNA Synthetase [Chlamydophila pneumoniae CWL029]
>gi|7189594|gb|AAF38490.1| (AE002226) valyl-tRNA
synthetase [Chlamydophila pneumoniae AR39]
>gi|8978467|dbj|BAA98304.1| (AP002545) alyl tRNA
synthetase [Chlamydophila pneumoniae J138]
Length = 940
Score = 101 bits (249), Expect = 5e-20
Identities = 75/279 (26%), Positives = 137/279 (48%), Gaps = 19/279 (6%)
Query: 8 REYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKD 67
+ Y+ + E ++ FW +N +++ E D P Y + PP V+G +H+G A ++D
Sbjct: 8 KAYNFQDTEPELYVFWEKNGMFKA--EASSDKPPYSVIMPPPNVTGVLHMGHALVNTLQD 65
Query: 68 MIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFAL 127
+++R++ M G+ V PG D G+ + VE+ L K E+F+K +
Sbjct: 66 VLVRYKRMSGFEVCWIPGTDHAGIATQAVVERHLQASEGKR-RTDYSREDFLKHIWAWKE 124
Query: 128 NNLKIMTEQFKMLGIWMDWDNPYMTIK---NEYIESAWFTLKRAWEKGLLEKDKRVLHWC 184
+ K++ Q + LG DWD T++ N ++ A+ TL +E G + + +++W
Sbjct: 125 KSEKVVLSQLRQLGCSCDWDRKRFTMEPLANRAVKKAFKTL---FENGYIYRGYYLVNWD 181
Query: 185 PRCETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDY 244
P +TALA+ EV EY+ + Y+++ + G + E +++ TT P T + ++ P+
Sbjct: 182 PVLQTALADDEV--EYEEKDGWLYYIRYRMVGSQ-ESIVVATTRPETSLGDTGIAVSPND 238
Query: 245 DY------VKVKVEFNGREEYWILAKALVDKVLGEIGVK 277
+ V+V F R + I+ A VD G VK
Sbjct: 239 ERYASWIGASVEVPFVNR-QIPIIGDASVDPTFGTGAVK 276
>gb|AAB49280.1| (U60901) isoleucyl-tRNA-synthetase [Bacillus subtilis]
Length = 121
Score = 101 bits (248), Expect = 6e-20
Identities = 48/103 (46%), Positives = 65/103 (62%), Gaps = 5/103 (4%)
Query: 16 EEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRTM 75
E ++K W E +IYR V+E KD PK+ DGPPY +G IH+G A NKI+KD I+R+++M
Sbjct: 24 EPDIQKKWEEEDIYRLVQERTKDRPKFVLHDGPPYANGDIHMGHALNKILKDFIVRYKSM 83
Query: 76 QGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENF 118
GYN PG+D HGLPIE + K KK +++ V F
Sbjct: 84 SGYNAPYVPGWDTHGLPIETAL-----TKNKKVNRKEMSVAEF 121
>pir||S77848 probable valine--tRNA ligase (EC 6.1.1.9) - Mycoplasma capricolum
(fragment)
Length = 260
Score = 97.1 bits (238), Expect = 9e-19
Identities = 62/225 (27%), Positives = 113/225 (49%), Gaps = 10/225 (4%)
Query: 582 IVEGEDQVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVE 641
+V G D + W ++ + +P++ V +HG V DE KMSKSLGN I P +V+
Sbjct: 19 LVTGYDIIFFWVAGNDFSNFRIYK-IPFKDVLIHGLVRDELNRKMSKSLGNGIDPMDVIN 77
Query: 642 RAGRDTFRFYMLWATNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLN 701
G D+ R ++L + P +++++S + + +N LWN AS Y+ L+ D + +
Sbjct: 78 NNGCDSLRLFLLTNSTPGQDIRYSNEKILASWNFINKLWN----ASRYVFLNLDDHFEFD 133
Query: 702 PD--ELPFREEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRK 759
P+ + ++WIL++++ + V + + + A L++FV WY+ +
Sbjct: 134 PNFYKTDLEITNQWILTQLSKTQAYVYEKMNKYEFSLAGNHLWDFVWNKYCSWYIEFSKV 193
Query: 760 RLWVEGEDPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLI 804
L D TL+ V +L +L P P+++EEIY N++
Sbjct: 194 NL---SNDKFNYQTKQTLFYVLKEILIMLHPLIPFVSEEIYLNMM 235
>gb|AAD36946.1|AF069441_6 (AF069441) putative leucyl tRNA synthetase [Arabidopsis thaliana]
>gi|7267192|emb|CAB77903.1| (AL161500) putative leucyl
tRNA synthetase [Arabidopsis thaliana]
Length = 973
Score = 96.3 bits (236), Expect = 2e-18
Identities = 60/190 (31%), Positives = 89/190 (46%), Gaps = 19/190 (10%)
Query: 8 REYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGA-IHLGTAWNKIIK 66
R Y ++E K +++W +N I+R ++ PK+Y LD PY SGA +H+G
Sbjct: 83 RVYPFHEIEPKWQRYWEDNRIFRTPDDVDTSKPKFYVLDMFPYPSGAGLHVGHPLGYTAT 142
Query: 67 DMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFA 126
D++ R R MQGYNV G+D GLP E + A+ T K
Sbjct: 143 DILARLRRMQGYNVLHPMGWDAFGLPAE---QYAIETGTHP---------------KTTT 184
Query: 127 LNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPR 186
L N+ Q K LG DWD T + +Y + + + ++KGL + + ++WCP
Sbjct: 185 LKNIDRFRLQLKSLGFSYDWDRELSTTEPDYYKWTQWIFLQLYKKGLAYQAEVPVNWCPA 244
Query: 187 CETALAEHEV 196
T LA EV
Sbjct: 245 LGTVLANEEV 254
>emb|CAC11908.1| (AL445065) leucyl-tRNA synthetase related protein [Thermoplasma
acidophilum]
Length = 910
Score = 95.6 bits (234), Expect = 3e-18
Identities = 186/861 (21%), Positives = 323/861 (36%), Gaps = 188/861 (21%)
Query: 15 LEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGP-PYVSGAIHLGTAWNKIIKDMIIRFR 73
+E K + W + I+ + DG K + + P PY +G++H+G + D+I R++
Sbjct: 19 IEAKWQNAWDRDGIFVP----KMDGRKKFMITVPWPYTNGSLHVGHGRTYTLGDIIARYK 74
Query: 74 TMQGYNVWRQPGYDMHGLPIEVKVEQ-------ALGLKTK--KEIEEK---IGVENFIKK 121
+ YNV G+ G PI E+ + L T KE EK +E+F K
Sbjct: 75 RSRNYNVLFPMGFHQSGTPILAFSERIRAGDRSTIDLYTSYLKEYGEKDIDALIESF-KD 133
Query: 122 CKEFALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVL 181
K A + FK LG +DW + + Y + + +R EKGL+++ + +
Sbjct: 134 PKNIADYFSNAIINDFKHLGYSIDWTRRFTSADEFYQKFVQWQFRRLNEKGLVKQGRYPI 193
Query: 182 HWCPRCETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAH 241
+ + A+ E +++ + Y GK + L+ + P T+ + +
Sbjct: 194 LYSLEDDNAVGEDDIKDGDTDKVTIEEYTAIFFRGKSFD-LIAASLRPETIYGITNIWVN 252
Query: 242 PDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDE 301
PD YVKVK+ +GR ++++ K+ + G + EV E +E++ Y
Sbjct: 253 PDVKYVKVKI--SGRMA--VVSEECSTKLKFQ-GNEIEVAGEASVQEIQKQTYT------ 301
Query: 302 YPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDF----------------- 344
P KE K V ADFV + GTG+V++ P H D+
Sbjct: 302 TPAGKEVK--------VYQADFVDPDNGTGIVYSVPSHSVYDYVYYRKKRGKDFPVIIEA 353
Query: 345 -----EVGQKYGLPV-----------------YSPLDDQGKYTEGKWKGIYVKEADPKII 382
++ KY L Y L D G YT G+ V+EA +
Sbjct: 354 PMKMKDIESKYDLETEEGREEATKDLYRNEFYYGKLVDSGPYT-----GMTVREAREAVK 408
Query: 383 EHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISK--VKDKIIKENDEKVTW 440
L G E ++ ++ DQWFL S+ +KD + +T
Sbjct: 409 RDLISSGNAFTFYETS-RHAVTRSGSKVIVAVLPDQWFLDYSQPWLKD-LGHTMINTMTM 466
Query: 441 YPDWVKIRFDNGVRDSGDWV----ISRQRYWGIPLPIWQSEDGEIYVVGSWRELVELAVA 496
+P+ + N + D+ DW+ +R+R G LP + +V+ S L + +
Sbjct: 467 HPE----VYRNVMNDAIDWLKERPCARRRGLGTRLPF-----DDRWVIES---LSDSTIY 514
Query: 497 IEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFD- 555
V I L YE KL + + R +++ + +D K + W+
Sbjct: 515 PAVYTNSIPLRSLYE------TGKLDDDAITRIFMNG---EPKNEDESEAKRQFEYWYPV 565
Query: 556 -------SGIASWASLGYPRNKELFEK-LWPADFIVEGEDQVTKWFYSQQAASIVAFDTV 607
I++ S + +F K WPA I+ G
Sbjct: 566 DIRLTAIPHISNHLSFYVLNHAAIFPKEKWPAGLIISG---------------------- 603
Query: 608 PYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENLKFSWK 667
++ G K+SKS GN++ E+ ++ D +R Y+
Sbjct: 604 ----------LVVSNGAKISKSKGNVVSLLEIAKKYSADIYRLYV--------------- 638
Query: 668 GVEQVRRMLNILWNVYVLASTYMSLDNFDPR----KLNPDELPFREEDKWILSRVNSLIS 723
Q + WN LAS + F K + +L F E+ W ++R + +
Sbjct: 639 -AVQADISSTMDWNETDLASITRRFNEFKDLMAGFKQDTSDLTF--EEAWFVARFSVRLR 695
Query: 724 EVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFDV 783
+ ++ + + A ++ V+ DL + L G D ++ L V
Sbjct: 696 QFMESMDRYQIRDAYINIFYGVLNDL---------RYLSSRGGDVNR-----ALTPVIAD 741
Query: 784 LLRLLAPFTPYIAEEIYQNLI 804
LR L P P+ AEE + + +
Sbjct: 742 WLRALMPVIPHHAEEYWHSYV 762
>sp|P36432|SYV_HAEPA VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|305375|gb|AAA20479.1| (L17342) Valyl-tRNA synthetase
[Haemophilus parainfluenzae]
Length = 378
Score = 95.6 bits (234), Expect = 3e-18
Identities = 66/246 (26%), Positives = 109/246 (43%), Gaps = 24/246 (9%)
Query: 624 DKMSKSLGNIIRPE--EVVERA------------GRDTFRFYMLWATNPWENLKFSWKGV 669
D + K GN+++P+ E + +A G D RF + + ++ + K +
Sbjct: 7 DLLEKRTGNMMQPQLAEKIAKATRKEFVDGIAAHGTDALRFTLAALASNGRDINWDMKRL 66
Query: 670 EQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISEVENGI 729
E R N LWN T LD L+ E+ F D+WI S N + + +
Sbjct: 67 EGYRNFCNKLWNASRFVLTNDKLD------LSQGEIEFSVADRWIQSEFNRTVESFRSAL 120
Query: 730 ESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFDVLLRLLA 789
+ A+Y F WY+ L K ++ G AA TL V + LLRL
Sbjct: 121 SQYRFDLCANAIYEFTWNQFCDWYLEL-TKPVFANGNAAQIRAASQTLVHVLEKLLRLAH 179
Query: 790 PFTPYIAEEIYQNLIRPFTNV--ESVHMLDWPKVDEKAIDEELEREMEFIRRIVEAGSAA 847
P P+I EEI+Q ++ F + +S+ + +P+V+E D E E E+E+++ ++ A
Sbjct: 180 PLIPFITEEIWQK-VKGFVGITADSIMLQPFPQVEENGFDPEAEAEIEWLKEVIVAVRNI 238
Query: 848 RQRAKI 853
R + I
Sbjct: 239 RAESNI 244
>sp|O66680|SYLA_AQUAE LEUCYL-TRNA SYNTHETASE ALPHA SUBUNIT (LEUCINE--TRNA LIGASE ALPHA
SUBUNIT) (LEURS) >gi|7519891|pir||D70331 leucine--tRNA
ligase (EC 6.1.1.4) alpha chain - Aquifex aeolicus
>gi|2983033|gb|AAC06643.1| (AE000685) leucyl-tRNA
synthetase alpha subunit [Aquifex aeolicus]
Length = 634
Score = 93.2 bits (228), Expect = 1e-17
Identities = 59/190 (31%), Positives = 95/190 (49%), Gaps = 23/190 (12%)
Query: 8 REYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKD 67
+E++P+++E+K +K W E ++ K +E + + K+Y L+ PY SG IH+G N I D
Sbjct: 3 KEFNPREIEKKWQKRWEEAGVF-KAQEGKPN--KFYVLEMFPYPSGRIHMGHVRNYTIGD 59
Query: 68 MIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFAL 127
I R+ M+G N+ G+D GLP E +++ I K +
Sbjct: 60 AIARYLKMRGKNILHPMGWDAFGLP-----------------AENAAIKHGIHPAK-WTY 101
Query: 128 NNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIE-SAWFTLKRAWEKGLLEKDKRVLHWCPR 186
N+ M +Q K+LG DWD T EY + + W LK E+G+ + ++WCP
Sbjct: 102 ENIDYMKKQLKILGFSYDWDREIATCDPEYYKWNQWIFLKML-ERGIAYRKTAKVNWCPH 160
Query: 187 CETALAEHEV 196
+T LA +V
Sbjct: 161 DQTVLANEQV 170
>dbj|BAB17162.1| (AP002868) putative leucyl-tRNA synthetase [Oryza sativa]
Length = 946
Score = 92.8 bits (227), Expect = 2e-17
Identities = 123/532 (23%), Positives = 187/532 (35%), Gaps = 140/532 (26%)
Query: 8 REYDPKKLEEKVEKFWSENEIYRKVK---ELRKDGPKYYFLDGPPYVSGA-IHLGTAWNK 63
R Y ++E + ++ W E+ +R L PK Y LD PY SGA +H+G
Sbjct: 63 RAYPYDEIEPRWQRHWEEHRTFRTPDIGHGLDTSKPKCYILDMFPYPSGAGLHVGHPLGY 122
Query: 64 IIKDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCK 123
D++ RF+ MQG+NV G+D GLP E + A+ T +I + + F +
Sbjct: 123 TATDILSRFKRMQGFNVLHPMGWDAFGLPAE---QYAIETGTHPKITTERNINRFRSQL- 178
Query: 124 EFALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHW 183
Q K LG DWD T + Y + + + ++GL + + ++W
Sbjct: 179 ------------QLKSLGFSYDWDREISTTEPTYYKWTQWIFLQLLKRGLAYQAEVPVNW 226
Query: 184 CPRCETALAEHEV------RGEYKLRKDPSIYVKFPV----------------------- 214
CP T LA EV RG + + + P +
Sbjct: 227 CPALGTVLANEEVIDGVSERGGHPVIRKPMRQWMLRITSYADRLLEDLDELDWPESIKEM 286
Query: 215 --------EGKENEY-------------LLIWTTTPWTLPANLAVSAHPDYDYVKVKVEF 253
EG E E+ LL++TT P T+ V P++ + +
Sbjct: 287 QRNWIGRSEGAELEFSAVDKEGHDLGANLLVYTTRPDTIFGATYVVLAPEHSLLSSLISE 346
Query: 254 NGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFKEKYE 313
R E +I A K E+ +E G + Y + E
Sbjct: 347 EQRVEEYIELTAR----------KSELERTDLQKEKTG-----VFSGSYAKNPATGEIVP 391
Query: 314 WAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLP---VYSPL----DDQGKYTE 366
+ +AD+V GTG + P H D E KY LP V SPL D + Y +
Sbjct: 392 ----IWVADYVLGSYGTGAIMAVPAHDSRDHEFALKYKLPIIKVVSPLNGNCDSEEAYAD 447
Query: 367 GKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKV 426
GI + + L G L K ++ +W
Sbjct: 448 ---DGIMINSSSSS--SGLNIDGMLSKDAALK-----------------VTEWVEANGFG 485
Query: 427 KDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSED 478
K K+ K+R DW+ +RQRYWG P P+ +D
Sbjct: 486 KKKVN-------------YKLR---------DWLFARQRYWGEPFPVIYRDD 515
>pir||F81974 leucine--tRNA ligase (EC 6.1.1.4) NMA0559 [similarity] - Neisseria
meningitidis (group A strain Z2491)
>gi|7379297|emb|CAB83851.1| (AL162753) putative
leucyl-tRNA synthetase [Neisseria meningitidis Z2491]
Length = 910
Score = 91.3 bits (223), Expect = 5e-17
Identities = 53/188 (28%), Positives = 88/188 (46%), Gaps = 20/188 (10%)
Query: 9 EYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDM 68
+Y P +E +K W + I+ ++ K PKYY L PY SG +H+G N I D+
Sbjct: 4 QYQPAAIEPAAQKKWDDARIFNVSEDASK--PKYYCLSMFPYPSGKLHMGHVRNYTIGDV 61
Query: 69 IIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALN 128
+ RF+ + G+NV + G+D G+P E ++N + + +
Sbjct: 62 LSRFKLLNGFNVMQPMGWDAFGMP-----------------AENAAMKNNVAPA-AWTYD 103
Query: 129 NLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCE 188
N++ M Q K LG +DW T K EY + + +EKG++ + ++W P +
Sbjct: 104 NIEYMKTQLKSLGFAIDWARETATCKPEYYRWEQWLFTKLFEKGIVYRKNGTVNWDPVDQ 163
Query: 189 TALAEHEV 196
T LA +V
Sbjct: 164 TVLANEQV 171
>pir||G81029 leucine--tRNA ligase (EC 6.1.1.4) NMB1897 [similarity] - Neisseria
meningitidis (group B strain MD58)
>gi|7227154|gb|AAF42228.1| (AE002539) leucyl-tRNA
synthetase [Neisseria meningitidis MC58]
Length = 876
Score = 90.5 bits (221), Expect = 9e-17
Identities = 53/188 (28%), Positives = 88/188 (46%), Gaps = 20/188 (10%)
Query: 9 EYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDM 68
+Y P +E +K W + I+ ++ K PKYY L PY SG +H+G N I D+
Sbjct: 4 QYRPAAIEPAAQKKWDDARIFNVSEDASK--PKYYCLSMFPYPSGKLHMGHVRNYTIGDV 61
Query: 69 IIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALN 128
+ RF+ + G+NV + G+D G+P E ++N + + +
Sbjct: 62 LSRFKLLNGFNVMQPMGWDAFGMP-----------------AENAAMKNNVAPA-AWTYD 103
Query: 129 NLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCE 188
N++ M Q K LG +DW T K EY + + +EKG++ + ++W P +
Sbjct: 104 NIEYMKTQLKSLGFAIDWARETATCKPEYYRWEQWLFTKLFEKGIVYRKNGTVNWDPVDQ 163
Query: 189 TALAEHEV 196
T LA +V
Sbjct: 164 TVLANEQV 171
>sp|Q9ZDB1|SYL_RICPR LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS)
>gi|7437545|pir||D71700 leucine--tRNA ligase (EC
6.1.1.4) (leuS) RP421 - Rickettsia prowazekii
>gi|3860978|emb|CAA14878.1| (AJ235271) LEUCYL-TRNA
SYNTHETASE (leuS) [Rickettsia prowazekii]
Length = 828
Score = 89.7 bits (219), Expect = 2e-16
Identities = 54/183 (29%), Positives = 89/183 (48%), Gaps = 20/183 (10%)
Query: 14 KLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFR 73
K+E+K +K W E + ++ E K PKYY L+ PY SG IH+G N I D+I RF
Sbjct: 3 KIEKKWQKIWQEEKAFQVSNESSK--PKYYVLEMLPYPSGKIHIGHVRNYSIGDVIARFM 60
Query: 74 TMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIM 133
TMQG+NV G+D GLP E ++N + +++ +N++ M
Sbjct: 61 TMQGFNVLHPMGWDAFGLP-----------------AENAAIKN-NSRPQDWTYSNIEYM 102
Query: 134 TEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAE 193
+Q + +G DW + EY + +++ L+ + + +++W P T LA
Sbjct: 103 KKQLQSMGFAYDWTREINSCDPEYYKHEQKFFLELYDRNLVYQKESLVNWDPVDNTVLAN 162
Query: 194 HEV 196
+V
Sbjct: 163 EQV 165
>dbj|BAA28840.1| (AB008526) Valyl tRNA Synthetase [Trichomonas vaginalis]
Length = 455
Score = 88.9 bits (217), Expect = 3e-16
Identities = 99/439 (22%), Positives = 188/439 (42%), Gaps = 56/439 (12%)
Query: 9 EYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDM 68
EY+P K+E +W EN+ + + K K K+ + PP V+G +HLG A I+D
Sbjct: 52 EYNPMKVENAWYSWW-ENQNFFEPKAADK---KFVMILPPPNVTGELHLGHALTASIEDA 107
Query: 69 IIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALN 128
I R+ M G PG D G+ + +VE+ + KK + E F+++ ++ +
Sbjct: 108 ITRYHRMCGEESLWVPGTDHAGIATQFRVEKKI-YDEKKLHRGEYSREYFLEEAHKWVES 166
Query: 129 NLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCE 188
+ Q + +G + W + Y T+ + ES + +++GL+ + +R+++W +
Sbjct: 167 KSGTILSQLRDMGSSLAWKDTYYTLDEKRSESVIAAFIKLFDEGLIYRSERLVNWDCALK 226
Query: 189 TALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPAN------LAVSAHP 242
TA+++ EV EY+ + T +P + V H
Sbjct: 227 TAISDAEV-----------------------EYITLTKRTKLNVPNHKYPQYPFGVMTHF 263
Query: 243 DYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEY 302
Y+ + G E +A ++ +LG+ V ++ + L G+ YV + E
Sbjct: 264 YYEICDKDGKKTG--EKVEIATTRLETMLGDTAVAIN-PKDARYNHLHGM-YVWHPIREV 319
Query: 303 PRQKEFKEKYEWAHRVILAD--FVTLEEGTGLVHTAPGHGEEDFEVGQKY-GLPVYSPLD 359
P I+ D V + GTG+V PGH D+EV +++ + + S L
Sbjct: 320 PIP-------------IIQDEILVDMNFGTGVVKVTPGHDPNDYEVYKRHPEIGLISILT 366
Query: 360 DQGKYTE--GKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATD 417
G G++ G+ +A ++++ ++E G + + E + R + T
Sbjct: 367 PDGAIASGYGQFSGMMRFDARVEMVKWMKEHGLYKEEKDHEMRLGITQRGHDIVEQVITP 426
Query: 418 QWFLKISKVKDKIIKENDE 436
QWF+ + + + IK D+
Sbjct: 427 QWFVNTTDMAARAIKAVDD 445
>pir||E83148 leucyl-tRNA synthetase PA3987 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9950178|gb|AAG07374.1|AE004816_10
(AE004816) leucyl-tRNA synthetase [Pseudomonas
aeruginosa]
Length = 873
Score = 88.9 bits (217), Expect = 3e-16
Identities = 54/188 (28%), Positives = 90/188 (47%), Gaps = 20/188 (10%)
Query: 9 EYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDM 68
+Y P ++E + + +W E++ + V+EL D K+Y L PY SG +H+G N I D+
Sbjct: 4 QYQPLEIETQAQNYWKEHQSFL-VREL-PDKEKFYCLSMFPYPSGKLHMGHVRNYTIGDV 61
Query: 69 IIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALN 128
I R+ MQG NV + G+D G+P E ++N + + +
Sbjct: 62 ISRYHRMQGRNVLQPMGWDAFGMP-----------------AENAAMKNNVAPA-AWTYD 103
Query: 129 NLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCE 188
N+ M Q LG+ +DW T K +Y + R +EKG++ + ++W P +
Sbjct: 104 NIAYMKSQLDSLGLAIDWSREVTTCKPDYYRWEQWLFTRLFEKGVIYRKNGTVNWDPVDQ 163
Query: 189 TALAEHEV 196
T LA +V
Sbjct: 164 TVLANEQV 171
>dbj|BAA28841.1| (AB008527) Valyl tRNA Synthetase [Trichomonas vaginalis]
Length = 455
Score = 88.5 bits (216), Expect = 3e-16
Identities = 99/439 (22%), Positives = 188/439 (42%), Gaps = 56/439 (12%)
Query: 9 EYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDM 68
EY+P K+E +W EN+ + + K K K+ + PP V+G +HLG A I+D
Sbjct: 52 EYNPMKVENAWYSWW-ENQNFFEPKAADK---KFVMILPPPNVTGELHLGHALTASIEDA 107
Query: 69 IIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALN 128
I R+ M G PG D G+ + +VE+ + KK + E F+++ ++ +
Sbjct: 108 ITRYHRMCGEESLWVPGTDHAGIATQFRVEKKI-YDEKKLHRGEYSREYFLEEAHKWVES 166
Query: 129 NLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCE 188
+ Q + +G + W + Y T+ + ES + +++GL+ + +R+++W +
Sbjct: 167 KSGTILSQLRDMGSSLAWKDTYYTLDEKRSESVIAAFIKLFDEGLIYRSERLVNWDCALK 226
Query: 189 TALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPAN------LAVSAHP 242
TA+++ EV EY+ + T +P + V H
Sbjct: 227 TAISDAEV-----------------------EYITLTKRTKLNVPNHKYPQYPFGVMTHF 263
Query: 243 DYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEY 302
Y+ + G E +A ++ +LG+ V ++ + L G+ YV + E
Sbjct: 264 YYEICDKDGKKTG--EKVEIATTRLETMLGDTAVAIN-PKDARYNHLHGM-YVWHPIREV 319
Query: 303 PRQKEFKEKYEWAHRVILAD--FVTLEEGTGLVHTAPGHGEEDFEVGQKY-GLPVYSPLD 359
P I+ D V + GTG+V PGH D+EV +++ + + S L
Sbjct: 320 PIP-------------IIQDEILVDMNFGTGVVKVTPGHDPNDYEVYKRHPEIGLISILT 366
Query: 360 DQGKYTE--GKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATD 417
G G++ G+ +A ++++ ++E G + + E + R + T
Sbjct: 367 PDGAIAPGYGQFSGMMRFDARVEMVKWMKEHGLYKEEKDHEMRLGITQRGHDIVEQVITP 426
Query: 418 QWFLKISKVKDKIIKENDE 436
QWF+ + + + IK D+
Sbjct: 427 QWFVNTTDMAARAIKAVDD 445
>gb|AAG20349.1| (AE005108) leucine-tRNA synthetase; LeuS [Halobacterium sp. NRC-1]
Length = 885
Score = 87.4 bits (213), Expect = 8e-16
Identities = 53/193 (27%), Positives = 88/193 (45%), Gaps = 21/193 (10%)
Query: 10 YDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMI 69
YD +E+ ++ W + +++R + D P+Y L PY SG +H+G N I D
Sbjct: 7 YDHHAIEQHWQREWDDADVFRVPDDA--DDPEYV-LAMFPYTSGQLHMGHVRNYAITDAF 63
Query: 70 IRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNN 129
R+R M G +V G+D GLP E E + ++C
Sbjct: 64 ARYRRMDGEDVLHPMGWDSFGLPAENAAN-----------ERDTNPREWTERC------- 105
Query: 130 LKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCET 189
+ M +QF+ LG DW+ T +Y + + + GL+++ ++WCP CET
Sbjct: 106 IDQMRDQFEALGFGYDWEREITTCDPDYYKWNQWLFTEFRDAGLVDRRAATVNWCPSCET 165
Query: 190 ALAEHEVRGEYKL 202
LA+ +V G+ +L
Sbjct: 166 VLADEQVEGDDEL 178
>sp|P37465|SYM_BACSU METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA LIGASE) (METRS)
>gi|2127140|pir||S66067 methionine--tRNA ligase (EC
6.1.1.10) metS - Bacillus subtilis
>gi|467427|dbj|BAA05273.1| (D26185) methionyl-tRNA
synthetase [Bacillus subtilis]
>gi|2632305|emb|CAB11814.1| (Z99104) methionyl-tRNA
synthetase [Bacillus subtilis]
Length = 664
Score = 85.8 bits (209), Expect = 2e-15
Identities = 119/491 (24%), Positives = 208/491 (42%), Gaps = 39/491 (7%)
Query: 423 ISKVKDKIIKENDEKVTWYPDWVKIR----------FDNGVRDSGDWVISRQRYWGIPLP 472
I KV K++ D + Y W I D + G+ + + G P+
Sbjct: 107 IEKVFQKLLDNGDIYLDEYEGWYSIPDETFYTETQLVDIERNEKGEVIGGKSPDSGHPVE 166
Query: 473 IWQSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVD 532
+ + E+ + +G + + L E N I+ PES + ++ K G EDL V
Sbjct: 167 LIK-EESYFFRMGKYAD--RLLKYYEENPTFIQ-PESRKNEMINNFIKPGLEDLA---VS 219
Query: 533 AFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYP-RNKELFEKLWPADFIVEGEDQVTK 591
K K VV VW D+ +LGY N EL++K WPAD + G++ + +
Sbjct: 220 RTTFDWGVKVPENPKHVVYVWIDALFNYLTALGYDTENDELYQKYWPADVHLVGKE-IVR 278
Query: 592 WFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFY 651
+ ++A D ++V HG++L + G KMSKS GN++ P ++ER G D R+Y
Sbjct: 279 FHTIYWPIMLMALDLPLPKQVFAHGWLLMKDG-KMSKSKGNVVDPVTLIERYGLDELRYY 337
Query: 652 MLWATNPWENLKFSWKG-VEQVR-RMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFRE 709
+L + F+ +G VE++ + N L N +L T ++ + ++ + E
Sbjct: 338 LLREVPFGSDGVFTPEGFVERINYDLANDLGN--LLNRTVAMINKYFDGQIGSYKGAVTE 395
Query: 710 EDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPD 769
D + S + E +E+ + A L+ + SR + WV +DP
Sbjct: 396 FDHTLTSVAEETVKAYEKAMENMEFSVALSTLWQLI----SRTNKYIDETAPWVLAKDPA 451
Query: 770 K----LAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKA 825
K + Y L + + LL PF E++++ L ES+ D +
Sbjct: 452 KEEELRSVMYHLAESLRISAVLLQPFLTKTPEKMFEQL---GITDESLKAWDSITAFGQL 508
Query: 826 IDEELEREMEFIRRIVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQ 885
D ++++ R+ A + K++ P + ET++E ++ V+RL I DQ
Sbjct: 509 KDTKVQKGEPLFPRLEAEEEIAYIKGKMQGSAPAKE---ETKEEEPQE-VDRLPEITIDQ 564
Query: 886 LNAKEVKVGRV 896
E++V V
Sbjct: 565 FMDVELRVAEV 575
>pir||T30889 valine--tRNA ligase (EC 6.1.1.9) - Giardia lamblia
>gi|3219290|dbj|BAA28839.1| (AB008525) Valyl tRNA
Synthetase [Giardia intestinalis]
Length = 1218
Score = 80.0 bits (194), Expect = 1e-13
Identities = 60/241 (24%), Positives = 115/241 (46%), Gaps = 8/241 (3%)
Query: 8 REYDPKKLEEKVEKFWSENEIYRK--VKELR-KDGP-KYYFLDGPPYVSGAIHLGTAWNK 63
+ Y+P +E+ ++W + K +R KD K+ L PP V+G++H+G A
Sbjct: 59 KAYNPSVIEKSWYEWWEAAGFFSPDMQKNIRSKDSRCKFTLLIPPPNVTGSLHIGHALTN 118
Query: 64 IIKDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCK 123
I+D ++R+ M GY PG D G+ + VE+ + +KT+ + +G E F+++
Sbjct: 119 SIQDALVRWYRMMGYRTLYLPGLDHAGIATQSVVERNI-MKTEGKTRHDLGRERFLERAW 177
Query: 124 EFALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHW 183
+ + Q ++LG DW T+ + + + +GL+ +D R+++W
Sbjct: 178 AWKEQFGGRILSQLRILGSSFDWSRSVFTLDPARSRVHNESFVKLFNRGLIYRDSRLVNW 237
Query: 184 CPRCETALAEHEVRGEY-KLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHP 242
+TA+++ EV EY L+ + V+ GK + +W + +P+ LA +
Sbjct: 238 DCSLQTAVSDVEV--EYIDLKLPRQLSVRNHDPGKSYPFGYLWRFSYKVIPSYLADKSEA 295
Query: 243 D 243
D
Sbjct: 296 D 296
>pir||G81698 leucyl-tRNA synthetase TC0481 [imported] - Chlamydia muridarum
(strain Nigg) >gi|7190521|gb|AAF39327.1| (AE002316)
leucyl-tRNA synthetase [Chlamydia muridarum]
Length = 819
Score = 79.2 bits (192), Expect = 2e-13
Identities = 60/208 (28%), Positives = 92/208 (43%), Gaps = 29/208 (13%)
Query: 10 YDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGA-IHLGTAWNKIIKDM 68
YDP +EEK +KFW E + +R ++ K KYY LD PY SGA +H+G D+
Sbjct: 3 YDPSLIEEKWQKFWKEEQTFRAEEDETK--TKYYVLDMFPYPSGAGLHVGHLIGYTATDI 60
Query: 69 IIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKT-KKEIEEKIGVENFIKKCKEFAL 127
+ R++ +G++V G+D GLP E + A+ T +E EK
Sbjct: 61 VARYKRAKGFSVLHPMGWDSFGLPAE---QYAIRTGTHPRETTEK--------------- 102
Query: 128 NNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRC 187
N+ +Q +G D + T EY + +EKGL +++CP
Sbjct: 103 -NIANFKQQLTSMGFSYDESREFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPEL 161
Query: 188 ETALAEHEVRGEYKLRKDPSIYVKFPVE 215
T L+ EV + S+ +PVE
Sbjct: 162 GTVLSNEEVENGF------SVEGGYPVE 183
>sp|O33925|SYM_THEMA METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA LIGASE) (METRS)
>gi|7437661|pir||E72297 methionine--tRNA ligase (EC
6.1.1.10) - Thermotoga maritima (strain MSB8)
>gi|2645225|gb|AAB87143.1| (U76417) methionyl-tRNA
synthetase [Thermotoga maritima]
>gi|4981630|gb|AAD36162.1|AE001768_11 (AE001768)
methionyl-tRNA synthetase [Thermotoga maritima]
Length = 629
Score = 78.8 bits (191), Expect = 3e-13
Identities = 104/423 (24%), Positives = 184/423 (42%), Gaps = 35/423 (8%)
Query: 396 EIEHKYPHCWR---CKTPLIFRATDQWFLKISKVKDKIIKENDEKVTW-YPDWVKIRFDN 451
E+ K+ W+ R TD+ +K + +KEN + Y W + +
Sbjct: 71 ELAEKFKRLWKELKITNDYFIRTTDEMHMKTVQEFVAKMKENGDVYKGIYKGWYCVPCET 130
Query: 452 GVRDSGDWVISRQRYWGIP---LPI-WQSEDGEIYVVGSWRELVELAVAIEVNGERIELP 507
+ D VI P P+ W E+ + + +R+ L E + + +E
Sbjct: 131 FWNE--DEVIKEGEERFCPECKRPVKWVEEENYFFRLSKYRD--SLLKYYEEHPDFVEPD 186
Query: 508 ESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYP 567
E LK++E L + R F V KD + V+ VW D+ I +++GY
Sbjct: 187 FRRNEMLKILEGGLKDLSITRT---TFKWGVPMKD--DPEHVIYVWVDALINYISAIGYG 241
Query: 568 RNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMS 627
N E+F K WPAD + G++ + ++ A +++ ++V HG+ L G K+S
Sbjct: 242 WNDEMFNKWWPADLHLIGKE-INRFHSIIWPAMLMSVGLPLPKKVFAHGW-LTVNGQKIS 299
Query: 628 KSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENLKFSWKGVEQVRRMLNILWNVY---V 684
KSLGN I P V+R G D R+Y++ ++ FS + + V R+ + L N Y +
Sbjct: 300 KSLGNAIDPRFFVKRYGNDVVRYYLIRDIMFGKDGDFSEERL--VHRLNSDLANDYGNLL 357
Query: 685 LASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISEVENGIESFYLTKATRALYNF 744
T M F+ R +P D W+ R ++S+ LT+A ++ F
Sbjct: 358 HRITAMIKKYFNGRLPSPSAQ--EGFDSWLKERFFETKDAYHELMDSYRLTEALDKIWEF 415
Query: 745 VVEDLSRWYVRLIRKRLWVEGEDPDK----LAAYYTLWKVFDVLLRLLAPFTPYIAEEIY 800
+ D+++++ + W+ G++ + Y +L VF V L L P P +EE++
Sbjct: 416 IA-DVNKYF---NDTKPWILGKEGNMERLGTVLYNSLEAVFKVALMTL-PVMPDTSEEVF 470
Query: 801 QNL 803
+ +
Sbjct: 471 RRV 473
>sp|O83595|SYL_TREPA LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS)
>gi|7437534|pir||C71305 leucine--tRNA ligase (EC
6.1.1.4) - syphilis spirochete
>gi|3322882|gb|AAC65562.1| (AE001234) leucyl-tRNA
synthetase (leuS) [Treponema pallidum]
Length = 878
Score = 75.7 bits (183), Expect = 3e-12
Identities = 54/191 (28%), Positives = 81/191 (42%), Gaps = 22/191 (11%)
Query: 10 YDPKKLEEKVEKFWSENEIYRKVKELRKDGP--KYYFLDGPPYVSG-AIHLGTAWNKIIK 66
Y + LE+K + +W + ++ V E + P + Y LD PY S +H+G
Sbjct: 3 YPFRALEKKWQAYWRDKRVFC-VSEDERFPPERRAYVLDMFPYPSAQGLHVGHPEGYTAT 61
Query: 67 DMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFA 126
D+ R+ M GYNV G+D GLP E AL T + + F ++ + F
Sbjct: 62 DIYCRYLRMGGYNVLHPMGFDAFGLPAE---NFALKTGTHPRVSTSANCDTFRRQIQSF- 117
Query: 127 LNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPR 186
G DW+ T EY + + +EKGL + ++WCP
Sbjct: 118 --------------GFSYDWEREISTADPEYYRWTQWLFLKLYEKGLAYEATAPINWCPS 163
Query: 187 CETALAEHEVR 197
C+T LA EVR
Sbjct: 164 CKTGLANEEVR 174
>gb|AAD50458.1|AF169967_1 (AF169967) LeuS [Flavobacterium johnsoniae]
Length = 233
Score = 73.7 bits (178), Expect = 1e-11
Identities = 47/151 (31%), Positives = 75/151 (49%), Gaps = 12/151 (7%)
Query: 9 EYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGA-IHLGTAWNKIIKD 67
+Y+P ++E K +K+W+EN+ + K PK+Y LD PY SGA +H+G I D
Sbjct: 2 KYNPNEIEAKWQKYWAENQTFAAKNNSEK--PKHYVLDMFPYPSGAGLHVGHPLGYIASD 59
Query: 68 MIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFI-KKCKEFA 126
+ RF+ QG+NV GYD GLP E + A+ + E ++ ++ + K+ K+ A
Sbjct: 60 VYSRFKRHQGFNVLHPMGYDSFGLPAE---QYAIQTGQRPEDTTRVNIDGGVDKEGKQIA 116
Query: 127 LNNLKIMTEQFKMLGIWMDWDNPYMTIKNEY 157
+Q +G DW T +Y
Sbjct: 117 -----GYRKQLDKIGFSFDWAREVRTSNPDY 142
>sp|P47508|SYL_MYCGE LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS)
>gi|1361707|pir||D64229 leucine--tRNA ligase (EC
6.1.1.4) - Mycoplasma genitalium
>gi|3844862|gb|AAC71488.1| (U39706) leucyl-tRNA
synthetase (leuS) [Mycoplasma genitalium]
Length = 792
Score = 71.4 bits (172), Expect = 5e-11
Identities = 72/280 (25%), Positives = 115/280 (40%), Gaps = 59/280 (21%)
Query: 426 VKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVG 485
+ +++I +N K+T K+R DW+ SRQRYWG P PI E+ ++V
Sbjct: 385 ITNELISQNKAKLTTV---YKLR---------DWIFSRQRYWGEPFPIIFDENNTPHLVE 432
Query: 486 SWRELVELAVAIEVNGERIELP--ESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDM 543
+ELP E+Y+ + G L R I+K N
Sbjct: 433 QLP---------------VELPLLENYKP------DGSGNSPLMRNQAWVNIVKDN-IHY 470
Query: 544 RRVKDVVDVWFDSGIASWASLGY--------------PRNKELFEKLWPADFIVEGEDQV 589
+R + + W S W LGY K+LF++ P D V G +
Sbjct: 471 QRETNTMPQWAGS---CWYYLGYLMLIKNPNFWPIDSKEAKKLFDQYLPVDLYVGGAEHA 527
Query: 590 TKWFYSQQAASIVAFDTV------PYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERA 643
+ FD P++++ G VL G KMSKS GN I P +V+
Sbjct: 528 VLHLLYARFWHKFLFDKKLVSTKEPFQKLINQGMVLGPDGKKMSKSKGNTINPTPLVDSH 587
Query: 644 GRDTFRFYMLWATNPWENLKFSWKGVEQVRRMLNILWNVY 683
G D R Y+++ +L ++ +G+ +RR L+ ++N +
Sbjct: 588 GADALRLYLMFMGPISASLTWNDEGLNGMRRWLDRVYNFF 627
>dbj|BAA28843.1| (AB008529) Valyl tRNA Synthetase [Trichomonas vaginalis]
Length = 368
Score = 71.4 bits (172), Expect = 5e-11
Identities = 64/243 (26%), Positives = 104/243 (42%), Gaps = 30/243 (12%)
Query: 640 VERAGRDTFRFYMLWATNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRK 699
+ + G D R + + + R N +WN A L NFD K
Sbjct: 24 IPQCGTDAMRLALCSFAGANRTANLNVSVIVSYRNFCNKMWNAVRFA-----LPNFD--K 76
Query: 700 LNP-------DELPFREEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRW 752
NP D DKW L +++ I G++ F + A + +F ++
Sbjct: 77 FNPEDSHKDLDASKTTPLDKWALKKLSLAIKAATAGLQDFKMADAVNGMTHFFHDEFCSV 136
Query: 753 YVRLIRKRLWVEGEDPD-KLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVE 811
Y+ I+ V G+D K L++ + +R+L PF PY+ EE++Q+L R F NVE
Sbjct: 137 YLEGIKPI--VNGDDAAAKEVVAAVLYECIESTMRMLHPFMPYVTEELWQHLPRRF-NVE 193
Query: 812 SVHMLDWPKVDEKAIDEELEREMEFIRRIVEAGSAARQRAKIKLRYPVRR-----IIIET 866
S+ + +P V+E E L ++ + SAAR IK +Y + II+ +
Sbjct: 194 SIMLAPYPLVNE----EWLNYDVSIVDTAFATASAAR---SIKKQYNINNNNLEAIIVTS 246
Query: 867 EDE 869
+DE
Sbjct: 247 QDE 249
>dbj|BAA28844.1| (AB008530) Valyl tRNA Synthetase [Trichomonas vaginalis]
Length = 368
Score = 70.6 bits (170), Expect = 9e-11
Identities = 64/243 (26%), Positives = 103/243 (42%), Gaps = 30/243 (12%)
Query: 640 VERAGRDTFRFYMLWATNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRK 699
+ + G D R + + + R N +WN A L NFD K
Sbjct: 24 IPQCGTDAMRLALCSFAGANRTANLNVSVIVSYRNFCNKMWNAVRFA-----LPNFD--K 76
Query: 700 LNP-------DELPFREEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRW 752
NP D DKW L +++ I G+E F + A + +F ++
Sbjct: 77 FNPEDSHKDLDASKTTPLDKWALKKLSLAIKAATAGLEDFKMADAVNGMTHFFHDEFCSV 136
Query: 753 YVRLIRKRLWVEGEDPD-KLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVE 811
Y+ + V G+D K L++ + +R+L PF PY+ EE++Q+L R F NVE
Sbjct: 137 YLEGTKPI--VNGDDAAAKEVVAAVLYECIESTMRMLHPFMPYVTEELWQHLPRRF-NVE 193
Query: 812 SVHMLDWPKVDEKAIDEELEREMEFIRRIVEAGSAARQRAKIKLRYPVRR-----IIIET 866
S+ + +P V+E E L ++ + SAAR IK +Y + II+ +
Sbjct: 194 SIMLAPYPLVNE----EWLNYDVSIVDTAFATASAAR---SIKKQYNINNNNLEAIIVTS 246
Query: 867 EDE 869
+DE
Sbjct: 247 QDE 249
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.319 0.139 0.425
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 431892572
Number of Sequences: 2977
Number of extensions: 19927100
Number of successful extensions: 60571
Number of sequences better than 1.0e-10: 206
Number of HSP's better than 0.0 without gapping: 85
Number of HSP's successfully gapped in prelim test: 121
Number of HSP's that attempted gapping in prelim test: 58693
Number of HSP's gapped (non-prelim): 603
length of query: 1067
length of database: 189,106,746
effective HSP length: 55
effective length of query: 1012
effective length of database: 156,189,961
effective search space: 158064240532
effective search space used: 158064240532
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 170 (70.6 bits)