BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0626 (pacS) DE:cation-transporting ATPase, P-type (pacS)
(689 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||E75141 cation-transporting atpase, p-type (pacs) PAB0626 - ... 1341 0.0
sp|Q59998|ATZN_SYNY3 ZINC-TRANSPORTING ATPASE (ZN(II)-TRANSLOCAT... 763 0.0
pir||D70041 heavy metal-transporting ATPase homolog yvgW - Bacil... 726 0.0
gb|AAA93043.1| (L46864) P type ATPase [Helicobacter pylori] 581 e-165
sp|Q59465|HMCT_HELPY CADMIUM, ZINC AND COBALT TRANSPORTING ATPAS... 580 e-164
sp|Q9ZL53|HMCT_HELPJ CADMIUM, ZINC AND COBALT TRANSPORTING ATPAS... 573 e-162
sp|Q9RQB4|HMCT_HELFE CADMIUM, ZINC AND COBALT TRANSPORTING ATPAS... 563 e-159
sp|P37386|CADD_STAAU PROBABLE CADMIUM-TRANSPORTING ATPASE (CADMI... 469 e-131
emb|CAB96929.1| (AJ251015) CadA protein [Stenotrophomonas maltop... 467 e-130
sp|P20021|CADA_STAAU PROBABLE CADMIUM-TRANSPORTING ATPASE (CADMI... 466 e-130
dbj|BAB07755.1| (AP001520) cadmium-transporting ATPase [Bacillus... 458 e-128
sp|P30336|CADA_BACFI PROBABLE CADMIUM-TRANSPORTING ATPASE (CADMI... 453 e-126
sp|Q60048|CADA_LISMO PROBABLE CADMIUM-TRANSPORTING ATPASE (CADMI... 442 e-123
gb|AAB37345.1| (U78967) cadmium resistance protein [Lactococcus ... 441 e-123
gb|AAF98300.1|AF243383_1 (AF243383) cadmium efflux ATPase CadA [... 441 e-122
pir||C75601 cation-transporting P-type ATPase - Deinococcus radi... 413 e-114
sp|P37617|ATZN_ECOLI ZINC-TRANSPORTING ATPASE (ZN(II)-TRANSLOCAT... 404 e-111
emb|CAA04762.1| (AJ001437) putative P-type cation-translocating ... 402 e-111
gb|AAG18768.1| (AE004981) zinc-transporting ATPase; ZntA [Haloba... 396 e-109
pir||C83185 probable metal-transporting P-type ATPase PA3690 [im... 395 e-109
pir||E69153 cadmium efflux ATPase - Methanobacterium thermoautot... 388 e-106
dbj|BAB04463.1| (AP001509) cadmium-transporting ATPase [Bacillus... 381 e-104
pir||G82251 cation transport ATPase, E1-E2 family VC1033 [import... 377 e-103
pir||S77012 cadmium-transporting ATPase (EC 3.6.1.-) cadA-1 - Sy... 377 e-103
pir||T08987 probable cadmium-transporting ATPase (EC 3.6.1.-) F6... 368 e-100
gb|AAD12041.1| (AC002392) putative cadmium-transporting ATPase [... 367 e-100
pir||F69869 heavy metal-transporting ATPase homolog ykvW - Bacil... 367 e-100
gi|11498084 cation-transporting ATPase, P-type (pacS) [Archaeogl... 359 5e-98
pir||T00532 probable cadmium-transporting ATPase (EC 3.6.1.-) - ... 359 5e-98
sp|O32220|ATCU_BACSU POTENTIAL COPPER-TRANSPORTING ATPASE >gi|74... 351 1e-95
pir||D72392 cation-transporting ATPase, P-type - Thermotoga mari... 346 4e-94
pir||G69071 heavy-metal-transporting ATPase (EC 3.6.1.-) MTH1535... 344 3e-93
sp|P77894|CTPV_MYCTU PROBABLE CATION-TRANSPORTING ATPASE V >gi|7... 342 6e-93
sp|Q9X5X3|ATCU_RHIME COPPER-TRANSPORTING ATPASE >gi|4680350|gb|A... 342 1e-92
dbj|BAB04276.1| (AP001508) copper-transporting ATPase [Bacillus ... 337 2e-91
gb|AAB01764.1| (U42410) heavy-metal transporting P-type ATPase [... 337 2e-91
sp|Q10866|CTPG_MYCTU PROBABLE CATION-TRANSPORTING ATPASE G >gi|7... 336 6e-91
gb|AAG10086.1|AF296446_2 (AF296446) CopA [Streptococcus mutans] 330 3e-89
pir||T03515 probable cadmium-transporting ATPase (EC 3.6.1.-) - ... 328 1e-88
sp|P32113|COPA_ENTHR COPPER/POTASSIUM-TRANSPORTING ATPASE A >gi|... 324 2e-87
pir||T35947 probable cation-transporting ATPase - Streptomyces c... 322 7e-87
emb|CAB81005.1| (AL161576) cadmium-transporting ATPase-like prot... 321 2e-86
sp|O53160|CTPD_MYCTU PROBABLE CATION-TRANSPORTING P-TYPE ATPASE ... 321 2e-86
gi|11497769 copper-transporting ATPase, P-type (copB) [Archaeogl... 318 1e-85
pir||H70798 probable cation-transporting ATPase - Mycobacterium ... 317 3e-85
gb|AAB06719.1| (U15554) P-type adenosine triphosphatase [Listeri... 316 4e-85
pir||H70396 cation transporting ATPase (E1-E2 family) - Aquifex ... 316 5e-85
pir||F72624 probable cation-transporting ATPase APE1454 - Aeropy... 315 1e-84
emb|CAB66270.1| (AL136519) probable cation-transporting P-type A... 312 8e-84
pir||F83156 probable metal transporting P-type ATPase PA3920 [im... 310 4e-83
pir||F83342 probable cation-transporting P-type ATPase PA2435 [i... 303 3e-81
pir||A81742 cation-transporting ATPase, E1-E2 family TC0100 [imp... 300 3e-80
sp|P37279|ATCS_SYNP7 CATION-TRANSPORTING ATPASE PACS >gi|480354|... 300 3e-80
pir||B71479 probable metal transport p-type ATPase - Chlamydia t... 299 8e-80
emb|CAB96031.1| (AL360055) putative metal transporter ATPase [St... 298 1e-79
sp|Q10876|CTPA_MYCTU CATION-TRANSPORTING P-TYPE ATPASE A >gi|743... 295 9e-79
pir||G75270 cation-transporting ATPase - Deinococcus radiodurans... 295 9e-79
gb|AAD11750.1| (AF067954) putative cation transporting P-type AT... 293 3e-78
pir||F70425 cation transporting ATPase (E1-E2 family) - Aquifex ... 291 1e-77
sp|O32619|COPA_HELFE COPPER-TRANSPORTING ATPASE >gi|11267397|pir... 290 4e-77
gi|11434161 ATPase, Cu++ transporting, beta polypeptide (Wilson ... 290 4e-77
gb|AAB52902.1| (U03464) ATP7B [Homo sapiens] 290 4e-77
pir||H82104 cation transport ATPase, E1-E2 family VC2215 [import... 289 7e-77
sp|P96875|CTPC_MYCTU PROBABLE CATION-TRANSPORTING P-TYPE ATPASE ... 288 1e-76
pir||T08988 cadmium-transporting ATPase homolog F6G3.150 - Arabi... 288 1e-76
pir||D72026 metal transport p-type ATPase - Chlamydophila pneumo... 287 3e-76
pir||C81515 cation-transporting ATPase, E1-E2 family CP1001 [imp... 287 3e-76
gi|4502323 ATPase, Cu++ transporting, beta polypeptide (Wilson d... 287 3e-76
gb|AAB94620.1| (AF032881) ATP7B [Ovis aries] 286 4e-76
gb|AAD39371.1|AF118225_1 (AF118225) ATP7B protein [Ovis aries] 286 4e-76
dbj|BAA84775.1| (AB017791) ATPase 7B [Rattus norvegicus] >gi|600... 286 8e-76
sp|P73241|ATCS_SYNY3 CATION-TRANSPORTING ATPASE PACS >gi|7428303... 285 1e-75
gb|AAC15948.1| (U82820) metal transporting ATPase Mta72 [Mycobac... 284 2e-75
sp|Q59385|ATCU_ECOLI PROBABLE COPPER-TRANSPORTING ATPASE >gi|742... 284 3e-75
gi|6978561 ATPase, Cu++ transporting, beta polypeptide (same as ... 283 5e-75
gi|6680758 ATPase, Cu++ transporting, beta polypeptide; Wilson p... 282 9e-75
emb|CAB65641.1| (AL136149) probable cation-transporting ATPase. ... 280 3e-74
pir||S40525 copper-transporting ATPase (EC 3.6.1.-) beta chain -... 280 3e-74
prf||2001422A Cu transporting ATPase P [Homo sapiens] 280 3e-74
pir||S76487 probable copper-transporting ATPase (EC 3.6.1.-) - S... 280 3e-74
gb|AAB02268.1| (U58330) probable copper-transporting atpase [Esc... 280 3e-74
pir||T36946 probable cation-transporting ATPase - Streptomyces c... 278 1e-73
sp|P05425|COPB_ENTHR COPPER/POTASSIUM-TRANSPORTING ATPASE B >gi|... 277 2e-73
sp|P77868|Y290_HAEIN PROBABLE CATION-TRANSPORTING ATPASE HI0290 ... 277 3e-73
dbj|BAA96520.1| (AB044355) ORFG [Pseudomonas syringae] 276 5e-73
sp|Q10877|CTPB_MYCTU CATION-TRANSPORTING P-TYPE ATPASE B >gi|743... 276 5e-73
pir||H69200 heavy-metal transporting CPx-type ATPase - Methanoba... 276 6e-73
sp|Q9X5V3|ATCU_RHILV COPPER-TRANSPORTING ATPASE >gi|4633808|gb|A... 275 8e-73
gb|AAD29109.1|AF082565_1 (AF082565) ATP dependent copper transpo... 275 8e-73
pir||A29576 H+/K+-exchanging ATPase (EC 3.6.1.36) - Enterococcus... 275 1e-72
pir||A82200 cation transport ATPase, E1-E2 family VC1437 [import... 274 2e-72
gb|AAG19186.1| (AE005015) molybdenum-binding protein; YvgX [Halo... 273 4e-72
pir||F81845 probable cation-transporting ATPase NMA1539 [importe... 273 6e-72
emb|CAC07984.1| (AJ278983) CopF Cu-ATPase [Ralstonia metallidurans] 272 1e-71
pir||D81097 cation transport ATPase, E1-E2 family NMB1325 [impor... 270 3e-71
sp|P46840|CTPB_MYCLE CATION-TRANSPORTING P-TYPE ATPASE B >gi|107... 269 8e-71
gb|AAK43003.1| Copper-transporting ATPase [Sulfolobus solfataricus] 268 1e-70
gb|AAF19707.1|AC008047_14 (AC008047) F2K11.18 [Arabidopsis thali... 268 2e-70
pir||C71250 probable cation-transporting ATPase, P-type - syphil... 266 4e-70
sp|P46839|CTPA_MYCLE CATION-TRANSPORTING P-TYPE ATPASE A >gi|107... 265 2e-69
dbj|BAA23769.1| (D89981) metal-transporting P-type ATPase [Arabi... 264 2e-69
pir||T40072 P Type Copper ATPase - fission yeast (Schizosaccharo... 264 3e-69
gi|4502321 ATPase, Cu++ transporting, alpha polypeptide (Menkes ... 263 6e-69
sp|Q04656|AT7A_HUMAN COPPER-TRANSPORTING ATPASE 1 (COPPER PUMP 1... 263 6e-69
emb|CAA20565.1| (AL031394) metal-transporting P-type ATPase (fra... 262 8e-69
pir||T06003 metal-transporting ATPase, P-type (EC 3.6.1.-) - Ara... 262 8e-69
gb|AAK42770.1| Cation transporting ATPase (pacS) [Sulfolobus sol... 261 1e-68
gb|AAD16009.1| (AF120492) night-specific ATPase [Rattus norvegicus] 259 9e-68
gi|6320475 Cu(2+)-transporting ATPase; Ccc2p [Saccharomyces cere... 257 3e-67
emb|CAB08162.2| (Z94801) Menkes Disease (ATP7A) [Homo sapiens] 257 3e-67
sp|Q9ZM69|COPA_HELPJ COPPER-TRANSPORTING ATPASE >gi|7436385|pir|... 256 5e-67
gb|AAA96010.1| (U27382) Menkes disease gene [Homo sapiens] 256 6e-67
pir||JC2464 probable copper-transporting ATPase (EC 3.6.1.-) HRA... 254 2e-66
emb|CAB16773.1| (Z99707) Cu2+-transporting ATPase-like protein [... 252 9e-66
sp|Q59467|COA2_HELPY COPPER-TRANSPORTING ATPASE >gi|1477772|gb|A... 252 1e-65
sp|O33533|FIXI_RHILV NITROGEN FIXATION PROTEIN FIXI (E1-E2 TYPE ... 251 2e-65
pir||E81320 probable cation-transporting ATPase Cj1155c [importe... 250 3e-65
pir||D81129 cation transport ATPase, E1-E2 family NMB1042 [impor... 249 8e-65
emb|CAB90352.1| (AJ400906) putative metal ATPase [Arabidopsis th... 249 8e-65
pir||C81835 probable P-type cation-transporting ATPase NMA1444 [... 249 1e-64
sp|O08462|COA3_HELPY COPPER-TRANSPORTING ATPASE >gi|2199521|gb|A... 248 2e-64
pir||D72491 probable heavy-metal transporting ATPase APE2571 - A... 248 2e-64
pir||C81321 probable cation-transporting ATPase Cj1161c [importe... 247 3e-64
sp|P55989|COPA_HELPY COPPER-TRANSPORTING ATPASE >gi|7428305|pir|... 246 5e-64
sp|P77871|COA1_HELPY COPPER-TRANSPORTING ATPASE 245 9e-64
sp|P18398|FIXI_RHIME NITROGEN FIXATION PROTEIN FIXI (E1-E2 TYPE ... 243 3e-63
emb|CAC12269.1| (AL445066) heavy-metal transporting P-type ATPas... 243 6e-63
sp|P37385|ATSY_SYNP7 PROBABLE COPPER-TRANSPORTING ATPASE SYNA >g... 235 1e-60
gb|AAB67320.1| (L33259) adenosine triphosphatase [Helicobacter p... 234 3e-60
gb|AAF63680.1|AF172726_3 (AF172726) copper P-type ATPase AtkB [L... 233 5e-60
gb|AAF44624.1|AF202779_3 (AF202779) RdxI [Rhodobacter sphaeroides] 232 9e-60
gb|AAF64237.1|AF249736_1 (AF249736) heavy metal transporter [Pse... 229 1e-58
pir||F83451 probable cation-transporting P-type ATPase PA1549 [i... 228 2e-58
pir||S60899 probable adenosinetriphosphatase (EC 3.6.1.3) - Heli... 225 1e-57
gb|AAC46114.1| (AF016223) CPx-type cation ATPase homolog [Rhodob... 224 2e-57
sp|Q59207|FIXI_BRAJA NITROGEN FIXATION PROTEIN FIXI (E1-E2 TYPE ... 222 7e-57
gb|AAA62114.1| (U16659) histidine rich P type ATPase [Escherichi... 221 2e-56
pir||JC2465 copper-transporting ATPase (EC 3.6.1.-) HRA-2 - Ente... 221 2e-56
pir||D82919 copper-transporting P-type ATPase UU203 [imported] -... 217 4e-55
dbj|BAA83939.1| (AB024559) YKVW [Bacillus halodurans] 213 6e-54
gb|AAG20331.1| (AE005106) heavy-metal transporting CPx-type ATPa... 207 4e-52
pir||A81338 H+/K+-exchanging ATPase (EC 3.6.1.36) B chain Cj0677... 201 3e-50
sp|O32328|ATKB_CLOAB POTASSIUM-TRANSPORTING ATPASE B CHAIN (ATP ... 198 2e-49
sp|P73867|ATKB_SYNY3 POTASSIUM-TRANSPORTING ATPASE B CHAIN (ATP ... 187 5e-46
pir||E71813 probable component of cation transport for cbb3-type... 186 6e-46
dbj|BAA07831.1| (D43776) P-type ATPase [Saccharomyces cerevisiae] 185 1e-45
gi|6319772 Putative P-type Cu(2+)-transporting ATPase; Pca1p [Sa... 185 2e-45
dbj|BAA84774.1| (AB017790) ATPase 7B [Rattus norvegicus] 182 9e-45
pir||A64453 H+-transporting ATPase (EC 3.6.1.35) - Methanococcus... 178 1e-43
pir||G64707 cation-transporting ATPase, P-type - Helicobacter py... 178 2e-43
gb|AAB05680.1| (U49498) Orf2; similar to Staphylococcus aureus S... 152 1e-35
gb|AAB06958.1| (U65004) P-type proton motive membrane ATPase [Pn... 147 3e-34
sp|Q07421|PMA1_AJECA PLASMA MEMBRANE ATPASE (PROTON PUMP) >gi|40... 139 7e-32
emb|CAB40585.1| (AJ010131) ykvW [Bacillus cereus] 137 4e-31
sp|P49380|PMA1_KLULA PLASMA MEMBRANE ATPASE (PROTON PUMP) >gi|59... 134 2e-30
sp|Q08436|PMA3_NICPL PLASMA MEMBRANE ATPASE 3 (PROTON PUMP 3) >g... 132 9e-30
sp|P54679|PMA1_DICDI PROBABLE PLASMA MEMBRANE ATPASE (PROTON PUM... 132 2e-29
sp|P09627|PMA1_SCHPO PLASMA MEMBRANE ATPASE 1 (PROTON PUMP 1) >g... 131 3e-29
pir||T05728 probable cadmium-transporting ATPase - soybean >gi|2... 120 7e-26
gi|11497808 A. fulgidus predicted coding region AF0191 [Archaeog... 118 3e-25
sp|P07893|ATSY_SYNP6 PROBABLE COPPER-TRANSPORTING ATPASE SYNA >g... 105 1e-21
pir||T31853 hypothetical protein C02E7.1 - Caenorhabditis elegan... 89 2e-16
dbj|BAA75381.1| (AB013371) YkvW [Bacillus halodurans] 84 4e-15
sp|P78036|ATCL_MYCPN PROBABLE CATION-TRANSPORTING P-TYPE ATPASE ... 77 5e-13
gb|AAB52420.1| (U93845) Arabidopsis thaliana ER-type calcium pu... 76 9e-13
gb|AAF75088.1|AC007583_24 (AC007583) Strong similarity to ER-typ... 76 9e-13
emb|CAA17934.1| (AL022118) putative cation-transporting ATPase [... 73 1e-11
emb|CAA04499.2| (AJ001045) P-type cation-transporting ATPase [Bl... 73 1e-11
pir||T43025 Na+/K+-exchanging ATPase (EC 3.6.1.37) alpha chain -... 73 1e-11
sp|P50996|ATHA_CANFA POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN (... 72 2e-11
pir||JN0903 H+/K+-exchanging ATPase (EC 3.6.1.36) alpha chain - dog 70 9e-11
gi|9055170 ATPase, H+/K+ transporting, alpha polypeptide [Mus mu... 70 9e-11
gi|11426740 ATPase, H+/K+ exchanging, alpha polypeptide [Homo sa... 70 9e-11
>pir||E75141 cation-transporting atpase, p-type (pacs) PAB0626 - Pyrococcus
abyssi (strain Orsay) >gi|5458357|emb|CAB49846.1|
(AJ248285) cation-transporting ATPase, P-type (pacS)
[Pyrococcus abyssi]
Length = 689
Score = 1341 bits (3433), Expect = 0.0
Identities = 689/689 (100%), Positives = 689/689 (100%)
Query: 1 MMPRKLKLEGLDCASCAYEIEEALRKEGFKFAVVNFATKEAIIEGDIEKAKEVIKKVEPD 60
MMPRKLKLEGLDCASCAYEIEEALRKEGFKFAVVNFATKEAIIEGDIEKAKEVIKKVEPD
Sbjct: 1 MMPRKLKLEGLDCASCAYEIEEALRKEGFKFAVVNFATKEAIIEGDIEKAKEVIKKVEPD 60
Query: 61 VEVVEEVHIHDHAHGEFEKRTIYFIGISLVLFTIGILMRYYYAIDNTLVFGLFLASYLIS 120
VEVVEEVHIHDHAHGEFEKRTIYFIGISLVLFTIGILMRYYYAIDNTLVFGLFLASYLIS
Sbjct: 61 VEVVEEVHIHDHAHGEFEKRTIYFIGISLVLFTIGILMRYYYAIDNTLVFGLFLASYLIS 120
Query: 121 GWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEYPEGVAVMLFYVIGEFLQDMAVDK 180
GWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEYPEGVAVMLFYVIGEFLQDMAVDK
Sbjct: 121 GWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEYPEGVAVMLFYVIGEFLQDMAVDK 180
Query: 181 SRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVD 240
SRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVD
Sbjct: 181 SRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVD 240
Query: 241 TSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKT 300
TSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKT
Sbjct: 241 TSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKT 300
Query: 301 EKFITRFAHYYTPAVVGIATLIATVPPLVFKESFTSWVYRALVILVISCPCALVLSIPLG 360
EKFITRFAHYYTPAVVGIATLIATVPPLVFKESFTSWVYRALVILVISCPCALVLSIPLG
Sbjct: 301 EKFITRFAHYYTPAVVGIATLIATVPPLVFKESFTSWVYRALVILVISCPCALVLSIPLG 360
Query: 361 YFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEIL 420
YFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEIL
Sbjct: 361 YFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEIL 420
Query: 421 RFAALAEAHSNHPIAKAIREAYGKEINEAEITEYEEIAGHGVRARIDSVEVMVGNDKLLH 480
RFAALAEAHSNHPIAKAIREAYGKEINEAEITEYEEIAGHGVRARIDSVEVMVGNDKLLH
Sbjct: 421 RFAALAEAHSNHPIAKAIREAYGKEINEAEITEYEEIAGHGVRARIDSVEVMVGNDKLLH 480
Query: 481 RSNIEHDTCKVKGTIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDS 540
RSNIEHDTCKVKGTIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDS
Sbjct: 481 RSNIEHDTCKVKGTIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDS 540
Query: 541 RDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVG 600
RDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVG
Sbjct: 541 RDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVG 600
Query: 601 VAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGLGI 660
VAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGLGI
Sbjct: 601 VAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGLGI 660
Query: 661 FGKATMWEAVFADVGVALIAVFNAMRVLR 689
FGKATMWEAVFADVGVALIAVFNAMRVLR
Sbjct: 661 FGKATMWEAVFADVGVALIAVFNAMRVLR 689
>sp|Q59998|ATZN_SYNY3 ZINC-TRANSPORTING ATPASE (ZN(II)-TRANSLOCATING P-TYPE ATPASE)
>gi|7428306|pir||S77015 cadmium-transporting ATPase (EC
3.6.1.-) cadA-2 - Synechocystis sp. (strain PCC 6803)
>gi|1001826|dbj|BAA10707.1| (D64005)
cadmium-transporting ATPase [Synechocystis sp.]
Length = 721
Score = 763 bits (1950), Expect = 0.0
Identities = 394/714 (55%), Positives = 517/714 (72%), Gaps = 30/714 (4%)
Query: 4 RKLKLEGLDCASCAYEIEEAL-RKEGFKFAVVNFATKEAIIEGDIEKAKEVIKK------ 56
+++++ G+DC SC +IE +L R +G A V AT + D ++ E+ +
Sbjct: 10 QQMQVGGMDCTSCKLKIEGSLERLKGVAEASVTVATGRLTVTYDPKQVSEITIQERIAAL 69
Query: 57 ----VEPDVEVV-----------EEVHIHDHAHGEFE-KRTIYFIGISLVLFTIGILMRY 100
EP V EE H H H GEF K+ + + ++ LFTI IL +
Sbjct: 70 GYTLAEPKSSVTLNGHKHPHSHREEGHSHSHGAGEFNLKQELLPVLTAIALFTIAIL--F 127
Query: 101 YYAIDNT----LVFGLFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKE 156
+ NT F + + +YL+SGW VLK+A N L G +FDENFL+ +AT+GA I +
Sbjct: 128 EQPLHNTPGQIAEFAVIIPAYLLSGWTVLKTAGRNILRGQIFDENFLMTIATLGALAIHQ 187
Query: 157 YPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGD 216
PE VAVMLF+ +GE Q+ +V +SRRSIKALL + + ANL R+GTV +V PE ++V D
Sbjct: 188 LPEAVAVMLFFRVGELFQEYSVGRSRRSIKALLEARPDTANLKRNGTVQQVSPETVQVDD 247
Query: 217 IIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTR 276
+I+VKPGEKVP+DG I+ GTS VDTSALTGES+P TVK GD IL+GMIN +G+L +RVT+
Sbjct: 248 LILVKPGEKVPLDGEILGGTSQVDTSALTGESVPGTVKPGDTILAGMINQSGVLTIRVTK 307
Query: 277 ELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKESFTS 336
SES+++++L+LVENAS++KA TEKFIT+FA YYTP +V ++ +A +PPL + +
Sbjct: 308 LFSESSIAKVLDLVENASSKKASTEKFITQFARYYTPVIVFLSLAVALLPPLFIPGADRA 367
Query: 337 -WVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKT 395
WVYRALV+LVISCPC LV+SIPLGYFGGIG AAK GILIKGS +LD+L V FDKT
Sbjct: 368 DWVYRALVLLVISCPCGLVISIPLGYFGGIGGAAKHGILIKGSTFLDSLTAVKTVVFDKT 427
Query: 396 GTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKEINEAEITEYE 455
GTLTKG FKVT++ T+NGF+E E+L AA AE+HS HPIA +IREAY + I ++E+ +YE
Sbjct: 428 GTLTKGTFKVTQVVTKNGFSESELLTLAAKAESHSTHPIALSIREAYAQSIADSEVADYE 487
Query: 456 EIAGHGVRARIDSVEVMVGNDKLLHRSNIEHDTCKVKGTIAHVVIDGQYAGYIVISDEIK 515
EIAGHG+RA + + V+ GND+LLHR I+HDTC V GT+ H+ +DG+Y GYI+I+DEIK
Sbjct: 488 EIAGHGIRAVVQNQVVIAGNDRLLHREKIDHDTCDVAGTVVHLAVDGRYGGYILIADEIK 547
Query: 516 EDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKE 575
EDA A+++LKR+GV K VM+TGDS VA+ +A+Q+GLD F AELLPE+KV IE+L
Sbjct: 548 EDAVQAIRDLKRMGVEKTVMLTGDSEIVAQSVAQQIGLDAFVAELLPEEKVDEIEQLLDP 607
Query: 576 KGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIAR 635
G KL FVGDGINDAPV+ARADVG+AMG LGSDAAIETADVV+M D PSK+ +AI +AR
Sbjct: 608 SGKAKLAFVGDGINDAPVIARADVGIAMGGLGSDAAIETADVVLMTDAPSKVAEAIHVAR 667
Query: 636 KTQRIVWENIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIAVFNAMRVLR 689
KT++IV +NI+ ALG+K FI LG G AT+WEAVFADVGVAL+A+ NA R+ +
Sbjct: 668 KTRQIVVQNIVLALGIKALFIALGTIGLATLWEAVFADVGVALLAILNATRIAK 721
>pir||D70041 heavy metal-transporting ATPase homolog yvgW - Bacillus subtilis
>gi|2635862|emb|CAB15354.1| (Z99121) similar to heavy
metal-transporting ATPase [Bacillus subtilis]
Length = 702
Score = 726 bits (1854), Expect = 0.0
Identities = 370/698 (53%), Positives = 497/698 (71%), Gaps = 11/698 (1%)
Query: 1 MMPRKLKLEGLDCASCAYEIEEALRK-EGFKFAVVNFATKEAIIEGDIEKAKEVIKKVEP 59
++ ++ L+GLDC++CA +IE ++ +G VNFA + D ++ + V KVE
Sbjct: 3 LVKQEYVLDGLDCSNCARKIENGVKGIKGINGCAVNFAASTLTVSADGKEEQWVTNKVEK 62
Query: 60 DVE------VVEEVHIHDHAHGEFEKRTIYFIGISLVLFTIGILMRYYYAIDNTLVFGLF 113
V+ V + HI A + R + + +G Y T+ F LF
Sbjct: 63 KVKSIDPHVTVRQKHIKKSADDGYRNRMVNMLIRMAAAVILGAAA--YLVQSGTIEFFLF 120
Query: 114 LASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEYPEGVAVMLFYVIGEFL 173
L +YLI G ++ A+ N + G VFDE+FL+A+ATIGAFLI++YPEGVAVMLFY IGE
Sbjct: 121 LGAYLIIGGDIIIRAVKNIIRGQVFDEHFLMALATIGAFLIQQYPEGVAVMLFYQIGELF 180
Query: 174 QDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVII 233
Q AV +SR+SI AL+ ++ +YANL + +V E+++ GDII+V PGE +P+DG ++
Sbjct: 181 QGAAVSRSRKSISALMDIRPDYANLKTKNGIEQVSSEDVQTGDIIVVNPGESIPLDGKVV 240
Query: 234 EGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENA 293
+G++ VDTSALTGES+PR EG +++SG IN G+L + VT+ ES VS+IL+LV+NA
Sbjct: 241 QGSAMVDTSALTGESVPRKAAEGQDVMSGFINQNGVLHIEVTKGYQESAVSKILDLVQNA 300
Query: 294 SARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFK-ESFTSWVYRALVILVISCPCA 352
S+RKA+TE FIT+FA YYTPAVV IA L+A VPPLV + + WVYRAL+ LVISCPCA
Sbjct: 301 SSRKARTENFITKFAKYYTPAVVIIAVLLAFVPPLVLSGAALSDWVYRALIFLVISCPCA 360
Query: 353 LVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRN 412
LV+SIPLG+FGGIG A+K G+L+KGSNYL+AL FDKTGTLTKG F+VT+I+
Sbjct: 361 LVVSIPLGFFGGIGAASKAGVLVKGSNYLEALNQVKYAVFDKTGTLTKGSFEVTEIKPAE 420
Query: 413 GFTEEEILRFAALAEAHSNHPIAKAIREAYGKEINEAEITEYEEIAGHGVRARIDSVEVM 472
GFT++ +L AA AE HS HPIA+++R+AYGK ++ EI YEEI+GHG+ A+++ E++
Sbjct: 421 GFTKDRLLEAAAYAELHSQHPIAESVRKAYGKMLSSDEIESYEEISGHGIFAKVNGTEIL 480
Query: 473 VGNDKLLHRSNIEHDTCKVKGTIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRK 532
GN KL+ R IE + GTI HV +D +YAG I+I+DEIKEDA AV +LK LG+++
Sbjct: 481 AGNKKLMEREQIEDVPDENAGTIVHVAVDQRYAGAIIIADEIKEDAAQAVADLKSLGIKQ 540
Query: 533 VVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLE-KEKGNGKLVFVGDGINDA 591
M+TGDS+ E + KQLG+ YAELLP+DKV +E LE K + KL+FVGDGIND
Sbjct: 541 TAMLTGDSKQTGEAVGKQLGIGEVYAELLPQDKVAQVEALEAKLLPSEKLIFVGDGINDT 600
Query: 592 PVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGV 651
PVLARAD+GVAMG LGSDAA+E AD+V+M D+PSK+ +AI+IA++T+RIVW+NI FALGV
Sbjct: 601 PVLARADIGVAMGGLGSDAAVEAADIVLMTDQPSKIAEAIRIAKRTRRIVWQNIGFALGV 660
Query: 652 KLAFIGLGIFGKATMWEAVFADVGVALIAVFNAMRVLR 689
K F+ LG FG ATMWEAVF+DVGV L+AV NAMRV+R
Sbjct: 661 KAIFLILGAFGIATMWEAVFSDVGVTLLAVANAMRVMR 698
>gb|AAA93043.1| (L46864) P type ATPase [Helicobacter pylori]
Length = 686
Score = 581 bits (1482), Expect = e-165
Identities = 305/693 (44%), Positives = 460/693 (66%), Gaps = 24/693 (3%)
Query: 8 LEGLDCASCAYEIEEALRKEGF-KFAVVNFATKEAIIE-GDIEKAKEVIKKVEPDVEVVE 65
+ LDC CA ++E L K + K A +NF+T ++ D EK K IK+ EP + +
Sbjct: 6 IHNLDCPDCASKLERDLNKLDYVKKAQINFSTSRLFLDTSDFEKVKAFIKQNEPHLSL-- 63
Query: 66 EVHIHDHAHGEFEKRTIYF--IGISLVLFTIGILMRYYYA---IDNTLVFGLFLASYLIS 120
+ E ++ + F + +++ +F IL+ + I+ + F L L YL+S
Sbjct: 64 -------SFKEAAEKPLSFTPLIVTIAVFLGAILILHLNPSPLIEKAMFFVLALV-YLVS 115
Query: 121 GWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEYPEGVAVMLFYVIGEFLQDMAVDK 180
G V+ A G FDEN L+ +ATI AF + Y E V++M+FY GEFLQ +A+ +
Sbjct: 116 GKDVILGAFRGLRKGQFFDENALMLIATIAAFCVGAYEESVSIMVFYSAGEFLQKLAIAR 175
Query: 181 SRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVD 240
S++S+KAL+ + A L + +V V PE+L++ DI++VK GEKVPVDGV+I+G S +D
Sbjct: 176 SKKSLKALVDVAPNLAYLKKGDALVSVAPEDLRINDIVVVKVGEKVPVDGVVIKGESLLD 235
Query: 241 TSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKT 300
AL+GESMP V E ++L G +NL +L+++V + +S+++++++LV+ A+ K++T
Sbjct: 236 ERALSGESMPVNVSERSKVLGGSLNLKAVLEIQVEKMYKDSSIAKVVDLVQQATNEKSET 295
Query: 301 EKFITRFAHYYTPAVVGIATLIATVPPLVFKESFTSWVYRALVILVISCPCALVLSIPLG 360
EKFIT+F+ YYTP+V+ IA +IA +PPL SF W+YR LV L++SCPCALV+S+PLG
Sbjct: 296 EKFITKFSRYYTPSVLFIALMIAVLPPLFSMGSFDEWIYRGLVALMVSCPCALVISVPLG 355
Query: 361 YFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEIL 420
YFGG+G A+++GIL+KG + L+ L A +AFDKTGTLTKGVFKVT I +NG ++EE+L
Sbjct: 356 YFGGVGAASRKGILMKGVHVLEVLTQAKSIAFDKTGTLTKGVFKVTDIVPQNGHSKEEVL 415
Query: 421 RFAALAEAHSNHPIAKAIREAYGKEI----NEAEITEYEEIAGHGVRARIDSVEVMVGND 476
+A+ ++ S HPIA +I+EA + + ++ +I YEE++G GV+A+ + ++ GN+
Sbjct: 416 HYASCSQLLSTHPIALSIQEACEEMLKDDKHQHDIKNYEELSGMGVKAQCHTDLIIAGNE 475
Query: 477 KLLHRSNIEHDTCKVKGTIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMV 536
K+L + +I H K GTI HV + Y GYIVISDEIK+DA +++LK G+ ++
Sbjct: 476 KMLDQFHIAHSPSKENGTIVHVAFNQTYIGYIVISDEIKDDAIECLRDLKAQGIENFCIL 535
Query: 537 TGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLAR 596
+GD + E IA+ LG + +YA LLPE+K + K KE+ +FVGDGINDAP LA
Sbjct: 536 SGDRKSATESIAQTLGCE-YYASLLPEEKTSVF-KTFKERYKAPAIFVGDGINDAPTLAS 593
Query: 597 ADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFI 656
ADVG+ MG GS+ + ++AD+VI +D + L K + IA+KT+ I+W+NI+FALG+K FI
Sbjct: 594 ADVGIGMGK-GSELSKQSADIVITNDSLNSLVKVLAIAKKTKSIIWQNILFALGIKAVFI 652
Query: 657 GLGIFGKATMWEAVFADVGVALIAVFNAMRVLR 689
LG+ G A++WEAVF DVGV L+A+ N+MR +R
Sbjct: 653 VLGLMGVASLWEAVFGDVGVTLLALANSMRAMR 685
>sp|Q59465|HMCT_HELPY CADMIUM, ZINC AND COBALT TRANSPORTING ATPASE
>gi|7436400|pir||G64618 cadmium-transporting ATPase,
P-type - Helicobacter pylori (strain 26695)
>gi|2313920|gb|AAD07839.1| (AE000591)
cadmium-transporting ATPase, P-type (cadA) [Helicobacter
pylori 26695]
Length = 686
Score = 580 bits (1478), Expect = e-164
Identities = 305/693 (44%), Positives = 459/693 (66%), Gaps = 24/693 (3%)
Query: 8 LEGLDCASCAYEIEEALRKEGF-KFAVVNFATKEAIIE-GDIEKAKEVIKKVEPDVEVVE 65
+ LDC CA ++E L + + K A +NF+T + ++ D EK K IK+ EP + +
Sbjct: 6 IHNLDCPDCASKLERDLNELDYVKKAQINFSTSKLFLDTSDFEKVKAFIKQNEPHLSL-- 63
Query: 66 EVHIHDHAHGEFEKRTIYF--IGISLVLFTIGILMRYYYA---IDNTLVFGLFLASYLIS 120
+ E ++ + F + I++++F IL+ + I+ + F L L YL+S
Sbjct: 64 -------SFKEATEKPLSFTPLIITIMVFLGAILILHLNPSPLIEKAMFFVLALV-YLVS 115
Query: 121 GWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEYPEGVAVMLFYVIGEFLQDMAVDK 180
G V+ A G FDEN L+ +ATI AF + Y E V++M+FY GEFLQ +AV +
Sbjct: 116 GKDVILGAFRGLRKGQFFDENALMLIATIAAFFVGAYEESVSIMVFYSAGEFLQKLAVSR 175
Query: 181 SRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVD 240
S++S+KAL+ + A L + +V V PE+L+V DI++VK GEKVPVDGV+++G S +D
Sbjct: 176 SKKSLKALVDVAPNLAYLKKGDELVSVAPEDLRVNDIVVVKVGEKVPVDGVVVKGESLLD 235
Query: 241 TSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKT 300
AL+GESMP V E ++L G +NL +L+++V + +S+++++++LV+ A+ K++T
Sbjct: 236 ERALSGESMPVNVSENSKVLGGSLNLKAVLEIQVEKMYKDSSIAKVVDLVQQATNEKSET 295
Query: 301 EKFITRFAHYYTPAVVGIATLIATVPPLVFKESFTSWVYRALVILVISCPCALVLSIPLG 360
EKFIT+F+ YYTP+V+ IA +IA +PPL SF W+YR LV L++SCPCALV+S+PLG
Sbjct: 296 EKFITKFSRYYTPSVLFIALMIAVLPPLFSMGSFDEWIYRGLVALMVSCPCALVISVPLG 355
Query: 361 YFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEIL 420
YFGG+G A+++GIL+KG + L+ L A +AFDKTGTLTKGVFKVT I +NG ++EE+L
Sbjct: 356 YFGGVGAASRKGILMKGVHVLEVLTQAKSIAFDKTGTLTKGVFKVTDIVPQNGHSKEEVL 415
Query: 421 RFAALAEAHSNHPIA----KAIREAYGKEINEAEITEYEEIAGHGVRARIDSVEVMVGND 476
+A+ ++ S HPIA KA E + ++ +I YEE++G GV+A+ + ++ GN+
Sbjct: 416 HYASCSQLLSTHPIALSIQKACEEMLKDDKHQHDIKNYEEVSGMGVKAQCHTDLIIAGNE 475
Query: 477 KLLHRSNIEHDTCKVKGTIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMV 536
K+L + +I H K GTI HV + Y GYIVISDEIK+DA +++LK G+ ++
Sbjct: 476 KMLDQFHIAHSPSKENGTIVHVAFNQTYVGYIVISDEIKDDAIECLRDLKVQGIENFCIL 535
Query: 537 TGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLAR 596
+GD + E IA+ LG + ++A LLPE+K + K KE+ +FVGDGINDAP LA
Sbjct: 536 SGDRKSATESIAQTLGCE-YHASLLPEEKTSVF-KTFKERYKAPAIFVGDGINDAPTLAS 593
Query: 597 ADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFI 656
ADVG+ MG GS+ + ++AD+VI +D + L K + IA+KT+ I+W+NI+FALG+K FI
Sbjct: 594 ADVGIGMGK-GSELSKQSADIVITNDSLNSLVKVLAIAKKTKSIIWQNILFALGIKAVFI 652
Query: 657 GLGIFGKATMWEAVFADVGVALIAVFNAMRVLR 689
LG+ G A++WEAVF DVGV L+A+ N+MR +R
Sbjct: 653 VLGLMGVASLWEAVFGDVGVTLLALANSMRAMR 685
>sp|Q9ZL53|HMCT_HELPJ CADMIUM, ZINC AND COBALT TRANSPORTING ATPASE
>gi|7436401|pir||E71895 probable heavy-metal
cation-transporting p-type ATPase - Helicobacter pylori
(strain J99) >gi|4155291|gb|AAD06308.1| (AE001504)
putative HEAVY-METAL CATION-TRANSPORTING P-TYPE ATPASE
[Helicobacter pylori J99]
Length = 686
Score = 573 bits (1462), Expect = e-162
Identities = 304/692 (43%), Positives = 450/692 (64%), Gaps = 22/692 (3%)
Query: 8 LEGLDCASCAYEIEEALRKEGF-KFAVVNFATKEAIIE-GDIEKAKEVIKKVEPDVEVVE 65
+ LDC CA ++E L K + K A +NF+T + ++ D EK K IK+ EP + +
Sbjct: 6 IHNLDCPDCAAKLERDLNKLDYVKKAQINFSTSKLFLDTSDFEKVKAFIKQNEPHLSL-- 63
Query: 66 EVHIHDHAHGEFEKRTIYFIG----ISLVLFTIGILMRYYYAIDNTLVFGLFLASYLISG 121
+ E ++ + F I++ L I IL VF + YLISG
Sbjct: 64 -------SFKEAAEKPLSFTPLIATIAVFLGAILILHLEPSPFIEKAVFVVLALVYLISG 116
Query: 122 WKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEYPEGVAVMLFYVIGEFLQDMAVDKS 181
V+ A G FDEN L+ +ATI AF + Y E V++M+FY GEFLQ +A+ +S
Sbjct: 117 KDVILGAFRGLRKGQFFDENALMLIATIAAFCVGAYEESVSIMVFYSAGEFLQILAIARS 176
Query: 182 RRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDT 241
++S+KAL+ + A L + T+V V PE+L++ DI++VK GEKVPVDGV+I+G S +D
Sbjct: 177 KKSLKALVDVAPNLAYLKKGDTLVSVAPEDLRINDIVVVKVGEKVPVDGVVIKGESLLDE 236
Query: 242 SALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTE 301
AL+GESMP V E ++L G +NL +L+++V + +S+++++++LV+ A+ K++TE
Sbjct: 237 RALSGESMPVNVSERSKVLGGSLNLKAVLEIQVEKLYKDSSIAKVVDLVQQATNEKSETE 296
Query: 302 KFITRFAHYYTPAVVGIATLIATVPPLVFKESFTSWVYRALVILVISCPCALVLSIPLGY 361
KFIT+F+ YYTP+V+ IA +IA +PPL SF W+YR LV L++SCPCALV+S+PLGY
Sbjct: 297 KFITKFSRYYTPSVLFIALMIAVLPPLFSMGSFDEWIYRGLVALMVSCPCALVISVPLGY 356
Query: 362 FGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILR 421
FGG+G A+++GIL+KG + L+ L +AFDKTGTLTKGVFKV I +NG ++EE+L
Sbjct: 357 FGGVGAASRKGILMKGVHVLEVLTQTKSIAFDKTGTLTKGVFKVVDIVPQNGHSKEEVLH 416
Query: 422 FAALAEAHSNHPIA----KAIREAYGKEINEAEITEYEEIAGHGVRARIDSVEVMVGNDK 477
+A+ ++ S HPIA KA E + ++ +I YEE++G GV+A+ + ++ GN+K
Sbjct: 417 YASCSQLLSTHPIALSIQKACEEMLKDDKHQHDIKNYEELSGMGVKAQCHTDLIIAGNEK 476
Query: 478 LLHRSNIEHDTCKVKGTIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVT 537
+L + +I H GTI HV + Y GYIVISDEIK+DA +++LK G+ +++
Sbjct: 477 MLDQFHIAHSPSPENGTIVHVAFNQTYIGYIVISDEIKDDAIECLRDLKAQGIENFCILS 536
Query: 538 GDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARA 597
GD + E IA+ LG + ++A LLPE+K + K KE+ +FVGDGINDAP LA A
Sbjct: 537 GDRKSATESIARTLGCE-YHASLLPEEKTSVF-KTFKERYKAPAIFVGDGINDAPTLASA 594
Query: 598 DVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIG 657
DVG+ MG GS+ + ++AD+VI +D S L K + IA+KT+ I+W+NI+FALG+K FI
Sbjct: 595 DVGIGMGK-GSELSKQSADIVITNDSLSSLVKVLAIAKKTKSIIWQNILFALGIKAVFIV 653
Query: 658 LGIFGKATMWEAVFADVGVALIAVFNAMRVLR 689
LG+ G A++WEAVF DVGV L+A+ N+MR +R
Sbjct: 654 LGLMGVASLWEAVFGDVGVTLLALANSMRTMR 685
>sp|Q9RQB4|HMCT_HELFE CADMIUM, ZINC AND COBALT TRANSPORTING ATPASE
>gi|6465953|gb|AAF12735.1| (AF125316) putative
cadmium-exporting P-type ATPase [Helicobacter felis]
Length = 681
Score = 563 bits (1435), Expect = e-159
Identities = 303/690 (43%), Positives = 454/690 (64%), Gaps = 15/690 (2%)
Query: 4 RKLKLEGLDCASCAYEIEEALRKEGF-KFAVVNFATKEAIIEG-DIEKAKEVIKKVEPDV 61
+K GLDC CA ++E AL K+ + + A V F T ++ D+ KA +IK++EPD+
Sbjct: 2 QKYHFTGLDCPDCANKLESALNKQSYVQEARVVFNTNTLYLKTQDMPKALALIKQLEPDM 61
Query: 62 EVVEEVHIHDHAHGEFEKRTIYFIGISLVLFTIGILMRYYYAIDNTL--VFGLFLASYLI 119
E+ E+V E + I + +S+VL+ I + ++ A + L + L YL+
Sbjct: 62 ELSEQVQ------SEAKPSAIPLL-LSVVLYLIAVATIHFSAQNWALHLSYALLAGVYLV 114
Query: 120 SGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEYPEGVAVMLFYVIGEFLQDMAVD 179
+G V A+ N FDEN L+ ATI AF + + E V++M+FY GEFLQ +A+
Sbjct: 115 AGKDVFLGALRAIRNKQFFDENTLMLSATIAAFGVGAHEEAVSIMVFYSAGEFLQQLAIA 174
Query: 180 KSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSV 239
+S++S+ ALL + +A + +V+P L +GD++IVK GEK+P DGV++ G S +
Sbjct: 175 RSKQSLHALLDVAPNHAVRKVGQELQEVEPSALAIGDVVIVKVGEKIPTDGVVLRGESLL 234
Query: 240 DTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAK 299
D ALTGES+P VKE +L G INL G+L+++V++ ++S+V++I++LV NA ++K++
Sbjct: 235 DQKALTGESLPVNVKEHSAVLGGSINLKGVLEIQVSKLYADSSVAKIVDLVSNAVSQKSQ 294
Query: 300 TEKFITRFAHYYTPAVVGIATLIATVPPLVFKESFTSWVYRALVILVISCPCALVLSIPL 359
TEKFIT FA YYTPAV IA LIA VPPL+ F +W+YR L L++SCPCALV+S+PL
Sbjct: 295 TEKFITTFARYYTPAVFAIALLIALVPPLLGHGDFDTWIYRGLFALMVSCPCALVISVPL 354
Query: 360 GYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEI 419
GYFGG+G A++ GILIK L+AL +AFDKTGTL+KG F V + F++E++
Sbjct: 355 GYFGGVGAASRAGILIKSVQTLEALSQVKNIAFDKTGTLSKGEFNVIDVVPIAPFSKEDV 414
Query: 420 LRFAALAEAHSNHPIAKAIREAYGKEINEAEITEYEEIAGHGVRARIDSVEVMVGNDKLL 479
L+ A A+ S HPIA +I++AY ++ + E+ +Y+EI G GV+A S ++ GNDK+L
Sbjct: 415 LQHATCAQILSTHPIAISIQKAYKRQC-QHEVKDYQEIGGLGVQASCHSHLIIAGNDKML 473
Query: 480 HRSNIEHDTCKVKGTIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGD 539
H+ NI HDTC ++GTI HV +DG++ GYIV++D +K++A + LK G+ + +++GD
Sbjct: 474 HKYNIPHDTCSLEGTIVHVAVDGKHIGYIVVADTLKDNAKECLDGLKHAGIEHMCILSGD 533
Query: 540 SRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADV 599
+ +AK+L +YA LLPEDK+ + + + + K +FVGDGINDAP LARADV
Sbjct: 534 HEYSTKRVAKELDCP-YYANLLPEDKLNAFKDFQAQHAH-KSMFVGDGINDAPTLARADV 591
Query: 600 GVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGLG 659
++MG+ S + E+AD+VI ++ + K +IA+KT+RI+ ENIIFAL +K FI LG
Sbjct: 592 SMSMGS-ASQISKESADIVITNNSLESVLKVFKIAKKTKRIIIENIIFALAIKAMFIVLG 650
Query: 660 IFGKATMWEAVFADVGVALIAVFNAMRVLR 689
+ G A++WEAV DVGV LIA+ N+MR +R
Sbjct: 651 LSGDASLWEAVLGDVGVTLIALANSMRTMR 680
>sp|P37386|CADD_STAAU PROBABLE CADMIUM-TRANSPORTING ATPASE (CADMIUM EFFLUX ATPASE)
>gi|152978|gb|AAA26610.1| (L10909) E1-E2 cadmium efflux
adenosine triphosphatase [Staphylococcus aureus]
Length = 804
Score = 469 bits (1195), Expect = e-131
Identities = 262/714 (36%), Positives = 427/714 (59%), Gaps = 38/714 (5%)
Query: 7 KLEGLDCASCAYEIEEALRK-EGFKFAVVNFATKEAIIEG-----DIEKAK-----EVI- 54
++EG CA+CA + E+ +++ G + A VNF + + G ++EKA +VI
Sbjct: 94 RVEGFSCANCAGKFEKNVKQLAGVQDAKVNFGASKIDVYGNASVEELEKAGAFENLKVIP 153
Query: 55 -KKVEPDVEVVEEVHIHDHAHGEFEKRTIYFIGISLVLFTI----GILMRYYYAIDNTLV 109
K P ++ V+E D + EK Y +L+ T+ G L + DN +
Sbjct: 154 EKLANPSIQAVKE----DTKAPKEEKIPFYKKHSTLLFATLLIAFGYLSHFVNGEDNLVT 209
Query: 110 FGLFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEYPEGVAVMLFYVI 169
LF++S +I G+ + K N + + FD L+ VA IGA +I E+ E V++ + I
Sbjct: 210 SMLFVSSIVIGGYSLFKVGFQNLIRFD-FDMKTLMTVAVIGAAIIGEWAEASIVVILFAI 268
Query: 170 GEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIVKPGEKVPVD 229
E L+ ++D++R+SI++L+ + + A + R+G + + +++ VGDI+IVKPGEK+ +D
Sbjct: 269 SEALERFSMDRARQSIRSLMDIAPKEALVRRNGQEIMIHVDDIAVGDIMIVKPGEKIAMD 328
Query: 230 GVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILEL 289
G+II G S+V+ +A+TGES+P DE+ +G +N GLL+V++T+ + ++T+S+I+ L
Sbjct: 329 GIIINGVSAVNQAAITGESVPVAKTVDDEVFAGTLNEEGLLEVKITKYVEDTTISKIIHL 388
Query: 290 VENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKESFTSWVYRALVILVISC 349
VE A +A + F+ +FA YYTP ++ IA L+A VPPL F S+ +WVY+ L +LV+ C
Sbjct: 389 VEEAQGERAPAQAFVDKFAKYYTPIIMVIAALVAVVPPLFFGGSWDTWVYQGLAVLVVGC 448
Query: 350 PCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIE 409
PCALV++ P+ IG AAK+G+LIKG YL+ L +AFDKTGTLTKGV VT +
Sbjct: 449 PCALVITTPISIVSAIGNAAKKGVLIKGGVYLEELGAIKAIAFDKTGTLTKGVPVVTDFK 508
Query: 410 TRNGFTEE-EILRFAALAEAHSNHPIAKAIREAYGKE---INEAEITEYEEIAGHGVRAR 465
N EE E+ E S HP+A AI + ++ ++ + ++ I G G++
Sbjct: 509 VLNDQVEEKELFSIITALEYRSQHPLASAIMKKAEQDNITYSDVRVKDFTSITGRGIQGN 568
Query: 466 IDSVEVMVGNDKLLHRSNIEHDTC----KVK-----GTIAHVV-IDGQYAGYIVISDEIK 515
ID +G+ +L N+ + KVK G A ++ D G I ++DE++
Sbjct: 569 IDGTTYYIGSPRLFKELNVSDFSLEFENKVKVLQNQGKTAMIIGTDQTILGVIAVADEVR 628
Query: 516 EDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKE 575
E + + +L +LG+++ +M+TGD++ AE I +G+ +ELLP+DK+ I+K++ E
Sbjct: 629 ETSKNVILKLHQLGIKQTIMLTGDNQGTAEAIGAHVGVSDIQSELLPQDKLDYIKKMKAE 688
Query: 576 KGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIAR 635
GN + +GDG+NDAP LA + VG+AMG G+D AIETAD+ +M D SKLP A++++R
Sbjct: 689 HGN--VAMIGDGVNDAPALAASTVGIAMGGAGTDTAIETADIALMGDDLSKLPFAVRLSR 746
Query: 636 KTQRIVWENIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIAVFNAMRVLR 689
KT I+ NI FA+G+K+ + L I G T+W A+ +D+G ++ N++R++R
Sbjct: 747 KTLNIIKANITFAIGIKIIALLLVIPGWLTLWIAILSDMGATILVALNSLRLMR 800
>emb|CAB96929.1| (AJ251015) CadA protein [Stenotrophomonas maltophilia]
Length = 727
Score = 467 bits (1189), Expect = e-130
Identities = 252/710 (35%), Positives = 422/710 (58%), Gaps = 30/710 (4%)
Query: 7 KLEGLDCASCAYEIEEALRK-EGFKFAVVNFATKEAIIEG-----DIEKAKEVIK-KVEP 59
+++G CA+CA + E+ ++K G + A VNF + + G ++EKA KV P
Sbjct: 17 RVQGFTCANCAGKFEKNVKKIPGVQDAKVNFGASKIDVYGNASVEELEKAGAFENLKVSP 76
Query: 60 DVEVVEEVH-IHDHAHGEFEKRTIYFIGISLVLFT-----IGILMRYYYAIDNTLVFGLF 113
+ + + + D E++T ++ S +LF G L + DN + LF
Sbjct: 77 EKLANQTIQRVKDDTKAHKEEKTPFYKKHSTLLFATLLIAFGYLSHFVNGEDNLVTSMLF 136
Query: 114 LASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEYPEGVAVMLFYVIGEFL 173
+ S +I G+ + K N + + FD LI VA IGA +I ++ E V++ + I E L
Sbjct: 137 VGSIVIGGYSLFKVGFPNLIRFD-FDMKTLITVAVIGATIIGKWAEASIVVILFAISEAL 195
Query: 174 QDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVII 233
+ ++D++R+SI++L+ + + A + R+G + + +++ VGDI+IVKPGEK+ +DG+I+
Sbjct: 196 ERFSMDRARQSIRSLMDIAPKEALVRRNGQEIIIHVDDIAVGDIMIVKPGEKIAMDGIIV 255
Query: 234 EGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENA 293
G S V+ +A+TGES+P + DE+ +G +N GL++V++T+ + ++T+++I+ LVE A
Sbjct: 256 NGLSVVNEAAITGESVPVSKAVDDEVFAGTLNEEGLIEVKITKYVEDTTIAKIIHLVEEA 315
Query: 294 SARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKESFTSWVYRALVILVISCPCAL 353
+A + F+ +FA YYTP ++ IA L+A VPPL F S+ +WVY+ L +LV+ CPCAL
Sbjct: 316 QGERAPAQAFVDKFAKYYTPIIMVIAALVAVVPPLFFGGSWDTWVYQGLAVLVVGCPCAL 375
Query: 354 VLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNG 413
V+S P+ IG AAK+G+L+KG YL+ L D VAFDKTGTLTKGV VT E N
Sbjct: 376 VISTPISIVSAIGNAAKKGVLVKGGVYLEKLGDIKTVAFDKTGTLTKGVPVVTDFEVLND 435
Query: 414 FTEE-EILRFAALAEAHSNHPIAKAIREAYGKE---INEAEITEYEEIAGHGVRARIDSV 469
EE E+ E S HP+A AI + ++ + ++ E+ I G G++ ++
Sbjct: 436 QVEEKELFSTITALEYRSQHPLASAIMKKAEQDNIPYSNVQVEEFTSITGRGIKGIVNGT 495
Query: 470 EVMVGNDKLLHRSNIEHDTCKVKGTIAHVVIDGQYA----------GYIVISDEIKEDAH 519
+G+ KL N+ + + + + G+ A G I ++DE++E +
Sbjct: 496 TYYIGSPKLFKELNVSDFSLGFENNVKILQNQGKTAMIIGTEKTILGVIAVADEVRETSK 555
Query: 520 LAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNG 579
+++L +LG+++ +M+TGD++ A I +G+ +EL+P+DK+ I+K++ E N
Sbjct: 556 NVIQKLHQLGIKQTIMLTGDNQGTANAIGTHVGVSDIQSELMPQDKLDYIKKMQSEYDN- 614
Query: 580 KLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQR 639
+ +GDG+NDAP LA + VG+AMG G+D AIETAD+ +M D SKLP A++++RKT
Sbjct: 615 -VAMIGDGVNDAPALAASTVGIAMGGAGTDTAIETADIALMGDDLSKLPFAVRLSRKTLN 673
Query: 640 IVWENIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIAVFNAMRVLR 689
I+ NI FA+G+K+ + L I G T+W A+ +D+G ++ N++R++R
Sbjct: 674 IIKANITFAIGIKIIALLLVIPGWLTLWIAILSDMGATILVALNSLRLMR 723
>sp|P20021|CADA_STAAU PROBABLE CADMIUM-TRANSPORTING ATPASE (CADMIUM EFFLUX ATPASE)
>gi|79893|pir||A32561 cadmium-transporting ATPase (EC
3.6.1.-) [validated] - Staphylococcus aureus
>gi|150719|gb|AAB59154.1| (J04551) cadmium resistance
protein [Plasmid pI258]
Length = 727
Score = 466 bits (1186), Expect = e-130
Identities = 251/710 (35%), Positives = 422/710 (59%), Gaps = 30/710 (4%)
Query: 7 KLEGLDCASCAYEIEEALRK-EGFKFAVVNFATKEAIIEG-----DIEKAKEVIK-KVEP 59
+++G CA+CA + E+ ++K G + A VNF + + G ++EKA KV P
Sbjct: 17 RVQGFTCANCAGKFEKNVKKIPGVQDAKVNFGASKIDVYGNASVEELEKAGAFENLKVSP 76
Query: 60 DVEVVEEVH-IHDHAHGEFEKRTIYFIGISLVLFT-----IGILMRYYYAIDNTLVFGLF 113
+ + + + D E++T ++ S +LF G L + DN + LF
Sbjct: 77 EKLANQTIQRVKDDTKAHKEEKTPFYKKHSTLLFATLLIAFGYLSHFVNGEDNLVTSMLF 136
Query: 114 LASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEYPEGVAVMLFYVIGEFL 173
+ S +I G+ + K N + + FD L+ VA IGA +I ++ E V++ + I E L
Sbjct: 137 VGSIVIGGYSLFKVGFQNLIRFD-FDMKTLMTVAVIGATIIGKWAEASIVVILFAISEAL 195
Query: 174 QDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVII 233
+ ++D+SR+SI++L+ + + A + R+G + + +++ VGDI+IVKPGEK+ +DG+I+
Sbjct: 196 ERFSMDRSRQSIRSLMDIAPKEALVRRNGQEIIIHVDDIAVGDIMIVKPGEKIAMDGIIV 255
Query: 234 EGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENA 293
G S+V+ +A+TGES+P + DE+ +G +N GL++V++T+ + ++T+++I+ LVE A
Sbjct: 256 NGLSAVNQAAITGESVPVSKAVDDEVFAGTLNEEGLIEVKITKYVEDTTITKIIHLVEEA 315
Query: 294 SARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKESFTSWVYRALVILVISCPCAL 353
+A + F+ +FA YYTP ++ IA L+A VPPL F S+ +WVY+ L +LV+ CPCAL
Sbjct: 316 QGERAPAQAFVDKFAKYYTPIIMVIAALVAVVPPLFFGGSWDTWVYQGLAVLVVGCPCAL 375
Query: 354 VLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNG 413
V+S P+ IG AAK+G+L+KG YL+ L VAFDKTGTLTKGV VT E N
Sbjct: 376 VISTPISIVSAIGNAAKKGVLVKGGVYLEKLGAIKTVAFDKTGTLTKGVPVVTDFEVLND 435
Query: 414 FTEE-EILRFAALAEAHSNHPIAKAIREAYGKE---INEAEITEYEEIAGHGVRARIDSV 469
EE E+ E S HP+A AI + ++ + ++ E+ I G G++ ++
Sbjct: 436 QVEEKELFSIITALEYRSQHPLASAIMKKAEQDNIPYSNVQVEEFTSITGRGIKGIVNGT 495
Query: 470 EVMVGNDKLLHRSNIEHDTCKVKGTIAHVVIDGQYA----------GYIVISDEIKEDAH 519
+G+ KL N+ + + + + G+ A G I ++DE++E +
Sbjct: 496 TYYIGSPKLFKELNVSDFSLGFENNVKILQNQGKTAMIIGTEKTILGVIAVADEVRETSK 555
Query: 520 LAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNG 579
+++L +LG+++ +M+TGD++ A I +G+ +EL+P+DK+ I+K++ E N
Sbjct: 556 NVIQKLHQLGIKQTIMLTGDNQGTANAIGTHVGVSDIQSELMPQDKLDYIKKMQSEYDN- 614
Query: 580 KLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQR 639
+ +GDG+NDAP LA + VG+AMG G+D AIETAD+ +M D SKLP A++++RKT
Sbjct: 615 -VAMIGDGVNDAPALAASTVGIAMGGAGTDTAIETADIALMGDDLSKLPFAVRLSRKTLN 673
Query: 640 IVWENIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIAVFNAMRVLR 689
I+ NI FA+G+K+ + L I G T+W A+ +D+G ++ N++R++R
Sbjct: 674 IIKANITFAIGIKIIALLLVIPGWLTLWIAILSDMGATILVALNSLRLMR 723
>dbj|BAB07755.1| (AP001520) cadmium-transporting ATPase [Bacillus halodurans]
Length = 707
Score = 458 bits (1166), Expect = e-128
Identities = 259/700 (37%), Positives = 413/700 (59%), Gaps = 28/700 (4%)
Query: 7 KLEGLDCASCAYEIEEALRK-EGFKFAVVNFATKEAIIEGD-----IEKAKEVIK-KVEP 59
+++G CA+CA E+ ++ G A VNF + + GD +E+A KV P
Sbjct: 15 RVQGFSCANCANTFEKNVKDLHGVVEAQVNFGASKLTVYGDATVEDLERAGAFEHLKVRP 74
Query: 60 DVE-VVEEVHIHDHAHGEFEKRTIYFIGISLVLFTIGILMRYYYAIDNTLVFGLFLASYL 118
+ E +E A+G + +S +L +G++ + + LF +S +
Sbjct: 75 ENEKAIETKEPFWKAYGH--------VIVSALLLLVGVVSYFMKGERHLWTVSLFASSIV 126
Query: 119 ISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEYPEGVAVMLFYVIGEFLQDMAV 178
I G+ + K+ N + FD L+ VA IGA LI E+ EG V++ + I E L+ ++
Sbjct: 127 IGGYSLFKAGFYNLIRLR-FDMKTLMTVAVIGAALIGEWLEGAVVVILFAISEALERFSM 185
Query: 179 DKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSS 238
D++R+SI++L+ + + A + R+G + + E ++VGDI+++KPG+K+ +DG++ G SS
Sbjct: 186 DRARQSIRSLVDMAPKEALVRRNGEELVIPVEAIEVGDIMLIKPGQKLAMDGIVRSGRSS 245
Query: 239 VDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKA 298
++ +A+TGES+P GD++ +G +N G L+V VT+ + ++T+++I+ LVE A +A
Sbjct: 246 MNEAAITGESVPVEKMVGDDVFAGTLNEEGFLEVEVTKRVEDTTLAKIIHLVEEAQGERA 305
Query: 299 KTEKFITRFAHYYTPAVVGIATLIATVPPLVFKESFTSWVYRALVILVISCPCALVLSIP 358
++ F+ FA YYTPA++ IA L+ATVPPL F S+ +W+Y+ L +LV+ CPCALV+S P
Sbjct: 306 PSQAFVDMFAKYYTPAIMVIAALVATVPPLFFAGSWETWIYQGLAVLVVGCPCALVISTP 365
Query: 359 LGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTE-E 417
+ IG AA+ GIL+KG YL+ VAFDKTGTLTKG VT + + T+
Sbjct: 366 VSIVTAIGNAARHGILVKGGIYLEEAARLRAVAFDKTGTLTKGKPAVTDYQVYDADTDGR 425
Query: 418 EILRFAALAEAHSNHPIAKAIREAYGKE---INEAEITEYEEIAGHGVRARIDSVEVMVG 474
E+L A E S HP+A A+ + E + E++E+ I G G+ ++ + + VG
Sbjct: 426 ELLAAVAALEYRSQHPLAAAVMKKADDEQLSYTDMEVSEFSSITGKGIAGTVNGIAINVG 485
Query: 475 NDKLLHR--SNIEHDTCKVKG---TIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLG 529
L IE D +++ TI + + + + ++DE++E + AV+ L LG
Sbjct: 486 KPALFGELPPAIEADVARLQAAGKTIMLIGAEQKVLALLAVADEVREVSRTAVERLHALG 545
Query: 530 VRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGIN 589
+ K VM+TGD+R A I KQ+G+ AELLPEDK+ ++ L++E +G++ VGDG+N
Sbjct: 546 ITKTVMLTGDNRMTARAIGKQVGVAEVEAELLPEDKLGFVKGLKEE--HGRVAMVGDGVN 603
Query: 590 DAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFAL 649
DAP LA + VGVAMG G+D A+ETADV +M D KLP I+++RK I+ ENI F+L
Sbjct: 604 DAPALAASSVGVAMGGAGTDTALETADVALMGDDLRKLPFLIRLSRKALLIIKENIAFSL 663
Query: 650 GVKLAFIGLGIFGKATMWEAVFADVGVALIAVFNAMRVLR 689
G+KL + L G T+W A+ AD+G L+ N +R+LR
Sbjct: 664 GIKLVALFLVAPGWLTLWIAILADMGATLLVTLNGLRLLR 703
>sp|P30336|CADA_BACFI PROBABLE CADMIUM-TRANSPORTING ATPASE (CADMIUM EFFLUX ATPASE)
>gi|282351|pir||D42707 probable cation-transporting
ATPase (EC 3.6.1.-) - Bacillus firmus
>gi|143753|gb|AAA22858.1| (M90750) cadmium-efflux ATPase
[Bacillus firmus]
Length = 723
Score = 453 bits (1153), Expect = e-126
Identities = 253/710 (35%), Positives = 417/710 (58%), Gaps = 33/710 (4%)
Query: 7 KLEGLDCASCAYEIEEALRK-EGFKFAVVNFATKEAIIEG-----DIEKAKEVIK-KVEP 59
+++G CA+CA + E+ +++ G + A VNF + + G ++EKA KV P
Sbjct: 17 RVQGFTCANCAGKFEKNVKQLSGVEDAKVNFGASKIAVYGNATIEELEKAGAFENLKVTP 76
Query: 60 DVEV------VEEVHIHDHAHGEFEKRTIYFIGISLVLFTIGILMRYYYAIDNTLVFGLF 113
+ V+E D + T+ + + L T G L Y +N + LF
Sbjct: 77 EKSARQASQEVKEDTKEDKVPFYKKHSTLLYASL---LITFGYLSSYVNGEENIVTTLLF 133
Query: 114 LASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEYPEGVAVMLFYVIGEFL 173
LAS I G + K + N L FD L+ VA IG +I E+ E V++ + I E L
Sbjct: 134 LASMFIGGLSLFKVGLQNLLRFE-FDMKTLMTVAVIGGAIIGEWAEVAIVVILFAISEAL 192
Query: 174 QDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVII 233
+ ++D++R+SI++L+ + + A + R+G + + +++ VGDI+IVKPG+K+ +DGV++
Sbjct: 193 ERFSMDRARQSIRSLMDIAPKEALVKRNGQEIMIHVDDIAVGDIMIVKPGQKIAMDGVVV 252
Query: 234 EGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENA 293
G S+V+ +A+TGES+P +E+ +G +N GLL+V +T+ + ++T+S+I+ LVE A
Sbjct: 253 SGYSAVNQTAITGESVPVEKTVDNEVFAGTLNEEGLLEVEITKLVEDTTISKIIHLVEEA 312
Query: 294 SARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKESFTSWVYRALVILVISCPCAL 353
+A ++ F+ +FA YYTP ++ IATL+A VPPL F S+ +W+Y+ L +LV+ CPCAL
Sbjct: 313 QGERAPSQAFVDKFAKYYTPIIMIIATLVAIVPPLFFDGSWETWIYQGLAVLVVGCPCAL 372
Query: 354 VLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRN- 412
V+S P+ IG AAK+G+L+KG YL+ + +AFDKTGTLTKGV VT N
Sbjct: 373 VISTPISIVSAIGNAAKKGVLVKGGVYLEEMGALKAIAFDKTGTLTKGVPAVTDYNVLNK 432
Query: 413 GFTEEEILRFAALAEAHSNHPIAKAIREAYGKE---INEAEITEYEEIAGHGVRARIDSV 469
E+E+L E S HP+A AI + +E ++ ++ ++ I G G++ ++
Sbjct: 433 QINEKELLSIITALEYRSQHPLASAIMKKAEEENITYSDVQVEDFSSITGKGIKGIVNGT 492
Query: 470 EVMVGNDKL---LHRSNIEHD------TCKVKGTIAHVV-IDGQYAGYIVISDEIKEDAH 519
+G+ KL L ++ + D T + +G A ++ + + I ++DE++E +
Sbjct: 493 TYYIGSPKLFKELLTNDFDKDLEQNVTTLQNQGKTAMIIGTEKEILAVIAVADEVRESSK 552
Query: 520 LAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNG 579
+++L +LG++K +M+TGD++ A I Q+G+ AEL+P+DK+ I++L E GN
Sbjct: 553 EILQKLHQLGIKKTIMLTGDNKGTANAIGGQVGVSDIEAELMPQDKLDFIKQLRSEYGN- 611
Query: 580 KLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQR 639
+ VGDG+NDAP LA + VG+AMG G+D A+ETADV +M D KLP ++++RKT
Sbjct: 612 -VAMVGDGVNDAPALAASTVGIAMGGAGTDTALETADVALMGDDLRKLPSTVKLSRKTLN 670
Query: 640 IVWENIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIAVFNAMRVLR 689
I+ NI FA+ +K L I G T+W A+ +D+G L+ N +R++R
Sbjct: 671 IIKANITFAIAIKFIASLLVIPGWLTLWIAILSDMGATLLVALNGLRLMR 720
>sp|Q60048|CADA_LISMO PROBABLE CADMIUM-TRANSPORTING ATPASE (CADMIUM EFFLUX ATPASE)
>gi|495646|gb|AAA25275.1| (L28104) ATPase [Listeria
monocytogenes]
Length = 711
Score = 442 bits (1125), Expect = e-123
Identities = 252/709 (35%), Positives = 409/709 (57%), Gaps = 34/709 (4%)
Query: 7 KLEGLDCASCAYEIEEALRK-EGFKFAVVNFATKEAIIEGD-----IEKAK--EVIKKVE 58
+++GL C +CA + E +++ EG A+VNF + + G+ +E+A E +K +
Sbjct: 8 RVDGLSCTNCAAKFERNVKEIEGVTEAIVNFGASKITVTGEASIQQVEQAGAFEHLKIIP 67
Query: 59 PDVEVVEEVHIHDHAHGEFEKRTIYFIGISLVLFTIGILMRYYYAIDNTLVFGLFLASYL 118
+ H DH F ++ + +S + +G + D L LF+ +
Sbjct: 68 EKESFTDPEHFTDHQ--SFIRKNWRLL-LSGLFIAVGYASQIMNGEDFYLTNALFIFAIF 124
Query: 119 ISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEYPEGVAVMLFYVIGEFLQDMAV 178
I G+ + K N L F L+ +A IGA I E+ EG V++ + + E L+ ++
Sbjct: 125 IGGYSLFKEGFKNLLKFE-FTMETLMTIAIIGAAFIGEWAEGSIVVILFAVSEALERYSM 183
Query: 179 DKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSS 238
DK+R+SI++L+ + + A + R GT V +++++GDI+I+KPG+K+ +DG +++G S+
Sbjct: 184 DKARQSIRSLMDIAPKEALVRRSGTDRMVHVDDIQIGDIMIIKPGQKIAMDGHVVKGYSA 243
Query: 239 VDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKA 298
V+ +A+TGES+P D + +G +N GLL+V VT+ + ++T+S+I+ LVE A +A
Sbjct: 244 VNQAAITGESIPVEKNIDDSVFAGTLNEEGLLEVAVTKRVEDTTISKIIHLVEEAQGERA 303
Query: 299 KTEKFITRFAHYYTPAVVGIATLIATVPPLVFKESFTSWVYRALVILVISCPCALVLSIP 358
+ F+ FA YYTPA++ IA LIATVPPL+F ++ +WVY+ L +LV+ CPCALV+S P
Sbjct: 304 PAQAFVDTFAKYYTPAIIVIAALIATVPPLLFGGNWETWVYQGLSVLVVGCPCALVVSTP 363
Query: 359 LGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTK----IETRNGF 414
+ IG AAK G+L+KG YL+ + +AFDKTGTLTKGV VT E N
Sbjct: 364 VAIVTAIGNAAKNGVLVKGGVYLEEIGGLKAIAFDKTGTLTKGVPVVTDYIELTEATNIQ 423
Query: 415 TEEEILRFAALAEAHSNHPIAKAIREAYGK----EINEAEITEYEEIAGHGVRARIDSVE 470
+ + AAL E S HP+A AI + YG+ ++ + ++ I G G+R +D
Sbjct: 424 HNKNYIIMAAL-EQLSQHPLASAIIK-YGETREMDLTSINVNDFTSITGKGIRGTVDGNT 481
Query: 471 VMVGNDKLLHRSNIEHDTCKVKGTIAHVVIDGQYA----------GYIVISDEIKEDAHL 520
VG+ L T + ++ + + G+ A + ++DE++ +
Sbjct: 482 YYVGSPVLFKELLASQFTDSIHRQVSDLQLKGKTAMLFGTNQKLISIVAVADEVRSSSQH 541
Query: 521 AVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGK 580
+K L LG+ K +M+TGD++ A+ I +Q+G+ EL+P+DK+ I++L + GK
Sbjct: 542 VIKRLHELGIEKTIMLTGDNQATAQAIGQQVGVSEIEGELMPQDKLDYIKQL--KINFGK 599
Query: 581 LVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRI 640
+ VGDGINDAP LA A VG+AMG G+D AIETADV +M D KLP ++++RKT +I
Sbjct: 600 VAMVGDGINDAPALAAATVGIAMGGAGTDTAIETADVALMGDDLQKLPFTVKLSRKTLQI 659
Query: 641 VWENIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIAVFNAMRVLR 689
+ +NI F+L +KL + L I G T+W A+ AD+G L+ N +R+++
Sbjct: 660 IKQNITFSLVIKLIALLLVIPGWLTLWIAIMADMGATLLVTLNGLRLMK 708
>gb|AAB37345.1| (U78967) cadmium resistance protein [Lactococcus lactis]
Length = 705
Score = 441 bits (1123), Expect = e-123
Identities = 246/707 (34%), Positives = 407/707 (56%), Gaps = 26/707 (3%)
Query: 1 MMPRKLKLEGLDCASCAYEIEEALRK-EGFKFAVVNFATKEAIIEGD--IEKAKEVIKK- 56
M + ++EGL C +CA + E+ +++ G A VNF + +EG IE+ +E
Sbjct: 5 MTEKTYRIEGLSCTNCAGKFEKNVKQLPGVTSATVNFGASKISVEGQTTIEELEEAGAFE 64
Query: 57 ---VEPDVEVVEEVHIHDHAHGEFEKRTIYFIGISLVLFTIGILMRYYYAIDNTLVFGLF 113
+ D E E+V + F KR I I ISL + ++ + D+ L L+
Sbjct: 65 NLIIRDDQENDEQVRSKE----SFIKRNIALI-ISLGFILVAVISQLSLGEDHLLTKALY 119
Query: 114 LASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEYPEGVAVMLFYVIGEFL 173
+ + +I G+ + K + + + F L+ +A IGA I E+ EG V++ + I E L
Sbjct: 120 ILAIIIGGFDLFKEGFSDLIKLD-FSMESLMTIAIIGAAFIGEWAEGSIVVILFAISEAL 178
Query: 174 QDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVII 233
+ ++DK+R+SI++L+ + + A + R+ V +++ + DI+I+KPG+K+ +DG++I
Sbjct: 179 ERFSMDKARQSIRSLMDIAPKEALIRRNNVEQLVSVDKIDIDDIMIIKPGQKIAMDGLVI 238
Query: 234 EGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENA 293
G SSV+ +A+TGES+P + DE+ +G +N G+L+V+VT++++++T+++I+ LVE A
Sbjct: 239 NGHSSVNQAAITGESVPVEKQLDDEVFAGTLNEEGILEVKVTKKVTDTTIAKIIHLVEEA 298
Query: 294 SARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKESFTSWVYRALVILVISCPCAL 353
+A + F+ +FA YYTP ++ +A LI VPPL F + W+Y+ L ILV+ CPC+L
Sbjct: 299 QGERAPAQAFVDKFAKYYTPFIIIMALLIVVVPPLFFGGDWNKWLYQGLSILVVGCPCSL 358
Query: 354 VLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNG 413
V+S P+ IG AAK G+L+KG YL+ + +AFDKTGTLTKG VT +
Sbjct: 359 VISTPVSIVSAIGNAAKNGVLVKGGVYLEEIGHLRAIAFDKTGTLTKGKPVVTDFIATSS 418
Query: 414 FTEEEILRFAALAEAHSNHPIAKAIREAYGK---EINEAEITEYEEIAGHGVRARIDSVE 470
T+ L + E+ S HP+A AI K + +I +++ I G G+ ++
Sbjct: 419 ETDINYLSIISSLESLSQHPLASAILNEADKTNVDYKSIQIEDFQSITGKGLTGIHQNIR 478
Query: 471 VMVGNDKLLHRSNIEHDTCKVK--------GTIAHVVIDGQYAGYIVISDEIKEDAHLAV 522
+G+ KL S IE KV+ T + D Q G I ++DE+++ + +
Sbjct: 479 YYIGSPKLFSASVIEETAVKVQYRQFQEQGKTAMYFGTDEQILGVIAVADEVRDSSAAVI 538
Query: 523 KELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLV 582
EL +L + +M+TGD+ AE I KQLG+ +L+P++K+ I+ L K+
Sbjct: 539 SELHKLSIEHTIMLTGDNTKTAESIGKQLGVTEIKGDLMPQEKLDSIKALRTT--YNKVA 596
Query: 583 FVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVW 642
VGDGINDAP LA + VG+AMG G+D A+ETADV +M D KLP ++++R+T +++
Sbjct: 597 MVGDGINDAPALAASTVGIAMGGAGTDTALETADVALMGDDLQKLPFIVRLSRQTLKVIK 656
Query: 643 ENIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIAVFNAMRVLR 689
+NI F+LG+KL + L I G T+W A+ AD+G L+ N +R+++
Sbjct: 657 QNITFSLGIKLLALLLVIPGWLTLWIAIVADMGATLLVTLNGLRLMK 703
>gb|AAF98300.1|AF243383_1 (AF243383) cadmium efflux ATPase CadA [Lactococcus lactis subsp.
lactis]
Length = 705
Score = 441 bits (1122), Expect = e-122
Identities = 246/707 (34%), Positives = 407/707 (56%), Gaps = 26/707 (3%)
Query: 1 MMPRKLKLEGLDCASCAYEIEEALRK-EGFKFAVVNFATKEAIIEGD--IEKAKEVIKK- 56
M + ++EGL C +CA + E+ +++ G A VNF + +EG IE+ +E
Sbjct: 5 MTEKTYRIEGLSCTNCAGKFEKNVKQLPGVTSATVNFGASKISVEGQTTIEELEEAGAFE 64
Query: 57 ---VEPDVEVVEEVHIHDHAHGEFEKRTIYFIGISLVLFTIGILMRYYYAIDNTLVFGLF 113
+ D E E+V + F KR I I ISL + ++ + D+ L L+
Sbjct: 65 NLIIRDDQENDEQVRSKE----SFIKRNIALI-ISLGFILVAVISQLSLGEDHLLTKALY 119
Query: 114 LASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEYPEGVAVMLFYVIGEFL 173
+ + +I G+ + K + + + F L+ +A IGA I E+ EG V++ + I E L
Sbjct: 120 ILAIIIGGFDLFKEGFSDLIKLD-FSMESLMTIAIIGAAFIGEWAEGSIVVILFAISEAL 178
Query: 174 QDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVII 233
+ ++DK+R+SI++L+ + + A + R+ V +++ + DI+I+KPG+K+ +DG++I
Sbjct: 179 ERFSMDKARQSIRSLMDIAPKEALIRRNNVEQLVSVDKIDIDDIMIIKPGQKIAMDGLVI 238
Query: 234 EGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENA 293
G SSV+ +A+TGES+P + DE+ +G +N G+L+V+VT++++++T+++I+ LVE A
Sbjct: 239 NGHSSVNQAAITGESVPVEKQLDDEVFAGTLNEEGVLEVKVTKKVTDTTIAKIIHLVEEA 298
Query: 294 SARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKESFTSWVYRALVILVISCPCAL 353
+A + F+ +FA YYTP ++ +A LI VPPL F + W+Y+ L ILV+ CPC+L
Sbjct: 299 QGERAPAQAFVDKFAKYYTPFIIIMALLIVVVPPLFFGGDWNKWLYQGLSILVVGCPCSL 358
Query: 354 VLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNG 413
V+S P+ IG AAK G+L+KG YL+ + +AFDKTGTLTKG VT +
Sbjct: 359 VISTPVSIVSAIGNAAKNGVLVKGGVYLEEIGHLRAIAFDKTGTLTKGKPVVTDFIATSS 418
Query: 414 FTEEEILRFAALAEAHSNHPIAKAIREAYGK---EINEAEITEYEEIAGHGVRARIDSVE 470
T+ L + E+ S HP+A AI K + +I +++ I G G+ ++
Sbjct: 419 ETDINYLSIISSLESLSQHPLASAILNEADKTNVDYKSIQIEDFQSITGKGLTGIHQNIR 478
Query: 471 VMVGNDKLLHRSNIEHDTCKVK--------GTIAHVVIDGQYAGYIVISDEIKEDAHLAV 522
+G+ KL S IE KV+ T + D Q G I ++DE+++ + +
Sbjct: 479 YYIGSPKLFSASVIEETAVKVQYRQFQEQGKTAMYFGTDEQILGVIAVADEVRDSSAAVI 538
Query: 523 KELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLV 582
EL +L + +M+TGD+ AE I KQLG+ +L+P++K+ I+ L K+
Sbjct: 539 SELHKLSIEHTIMLTGDNTKTAESIGKQLGVTEIKGDLMPQEKLDSIKALRTT--YNKVA 596
Query: 583 FVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVW 642
VGDGINDAP LA + VG+AMG G+D A+ETADV +M D KLP ++++R+T +++
Sbjct: 597 MVGDGINDAPALAASTVGIAMGGAGTDTALETADVALMGDDLQKLPFIVRLSRQTLKVIK 656
Query: 643 ENIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIAVFNAMRVLR 689
+NI F+LG+KL + L I G T+W A+ AD+G L+ N +R+++
Sbjct: 657 QNITFSLGIKLLALLLVIPGWLTLWIAIVADMGATLLVTLNGLRLMK 703
>pir||C75601 cation-transporting P-type ATPase - Deinococcus radiodurans
(strain R1) >gi|6460538|gb|AAF12244.1|AE001862_70
(AE001862) cation-transporting P-type ATPase
[Deinococcus radiodurans]
Length = 728
Score = 413 bits (1049), Expect = e-114
Identities = 262/725 (36%), Positives = 391/725 (53%), Gaps = 59/725 (8%)
Query: 8 LEGLDCASCAYEIEEALRK-EGFKFAVVNFATKEAIIEGD-IEKAKEVIKK--------- 56
+EG+DCA+C +E+ + G +F + +E D + ++ ++K
Sbjct: 12 VEGMDCANCVARVEKMVGGLPGTGEVKTSFTRQTLTLELDETQTSRAALEKNLRSLGYGP 71
Query: 57 -VEPDVEVV---EEVHIHDHA----------HGEFEK-RTIYFIGISLVLFTIGILMRYY 101
+ PD + E H HDHA H E+ + Y G ++ G+L+
Sbjct: 72 SLLPDRDAPQTGEGAHTHDHADHQHAGHSHSHDPAEQGKPWYRTGQGQLVVASGVLLALA 131
Query: 102 YAIDNTLVFGLF---------LASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAF 152
+ VFG F A+ L+ W + K A + G+ F N L+ +A IGA
Sbjct: 132 W------VFGRFEPAWAQWGYAAAALLGAWPLAKKAWASVRLGDPFSINLLVTLAAIGAV 185
Query: 153 LIKEYPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEEL 212
I + EG V+ + +GE L+ +A ++R I L AL + A LV G V +V + L
Sbjct: 186 AIGQAAEGAVVVFLFAVGELLEGVAAGRARAGIATLAALAPKTALLVEPGGVREVPADTL 245
Query: 213 KVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKV 272
+VG + V PG +VP DG I G SS+D S +TGES+P + GD + +G IN G+L V
Sbjct: 246 QVGQTVQVGPGARVPADGTITAGQSSLDDSPVTGESVPVSKGPGDHVYAGSINTDGVLTV 305
Query: 273 RVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKE 332
RV R +++T++RI+ LVE A + KA T +FI RF+ +YTP VV +A L A +PPL+ +
Sbjct: 306 RVDRAAADNTIARIIHLVEEAESSKAPTARFIDRFSRWYTPGVVAVAALTAALPPLLLGQ 365
Query: 333 SFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAF 392
+ W+Y+ + +L+I CPCALVLS+P GI + G+LIKG L+ + +AF
Sbjct: 366 PWYPWLYKGIALLLIGCPCALVLSVPAAITSGISAGTRRGLLIKGGAALETIGSVRTIAF 425
Query: 393 DKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAI-REAYGKEINEAEI 451
DKTGTLT G +VT + N E+LR AA E S+HP+A+AI EA + +
Sbjct: 426 DKTGTLTSGRPRVTDVLADN---PAELLRLAAAVETGSSHPLAQAITAEAQARGLTVPAA 482
Query: 452 TEYEEIAGHGVRARIDSVEVMV-------GNDKLLHRSNIEHDTCKVKGTIAHVVID-GQ 503
+E + G GV A ++ V V L T + +G V +D G+
Sbjct: 483 SEARALPGQGVTALVEGRPVQVTSPIFAASQATLSAEQQQTVATLEQQGRTVVVGLDGGR 542
Query: 504 YAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPE 563
G I + DE +EDA A+ EL+RLG+R +M+TGD+ + +A LGLD AELLP
Sbjct: 543 VLGLIALRDEPREDAREALAELRRLGIRP-LMLTGDNARTGQAVAADLGLD-VQAELLPA 600
Query: 564 DKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDK 623
DK+ II++L + G + VGDGINDAP LARADVG+AMG+ G+D A+ETAD ++ +
Sbjct: 601 DKLNIIDEL---RAQGGVAMVGDGINDAPALARADVGIAMGS-GTDVALETADAALLRGQ 656
Query: 624 PSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIAVFN 683
+ + +Q++R T + +N+ FALG+K F+ + G +W AV AD G I N
Sbjct: 657 VQGVGELVQLSRDTLANIRQNVAFALGLKAIFLVTTLLGYTNLWMAVLADTGATAIVTAN 716
Query: 684 AMRVL 688
A+R+L
Sbjct: 717 ALRLL 721
>sp|P37617|ATZN_ECOLI ZINC-TRANSPORTING ATPASE (ZN(II)-TRANSLOCATING P-TYPE ATPASE)
>gi|1073528|pir||S47688 hypothetical protein o732 -
Escherichia coli >gi|466605|gb|AAB18444.1| (U00039) No
definition line found [Escherichia coli]
>gi|1789879|gb|AAC76494.1| (AE000422) zinc-transporting
ATPase [Escherichia coli K12]
Length = 732
Score = 404 bits (1027), Expect = e-111
Identities = 246/691 (35%), Positives = 385/691 (55%), Gaps = 21/691 (3%)
Query: 7 KLEGLDCASCAYEIEEALRK-EGFKFAVVNFATKEAIIEGDIEKAKEVIKKVEPDVEVVE 65
K+ G+DCA+CA ++E A+R+ G V FAT++ +++ D + +V ++ +
Sbjct: 53 KVSGMDCAACARKVENAVRQLAGVNQVQVLFATEKLVVDADNDIRAQVESALQKAGYSLR 112
Query: 66 EVHIHDHAHGEFEKRTIYFIGISLVLFTIGILMRYYYAIDN-TLVFG--LFLASYLISGW 122
+ + K +L L T+ ++M + ++ FG F+A+ L+ +
Sbjct: 113 DEQAAEEPQASRLKE-------NLPLITLIVMMAISWGLEQFNHPFGQLAFIATTLVGLY 165
Query: 123 KVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEYPEGVAVMLFYVIGEFLQDMAVDKSR 182
+ + A+ +G+ F L++VA IGA I E V+L ++IGE L+ A ++R
Sbjct: 166 PIARQALRLIKSGSYFAIETLMSVAAIGALFIGATAEAAMVLLLFLIGERLEGWAASRAR 225
Query: 183 RSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTS 242
+ + AL+ALK E A +R G +V L+ GD+I V G ++P DG ++ +S D S
Sbjct: 226 QGVSALMALKPETATRLRKGEREEVAINSLRPGDVIEVAAGGRLPADGKLLSPFASFDES 285
Query: 243 ALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEK 302
ALTGES+P GD++ +G ++ L+ + V E S + RIL+L+E A R+A E+
Sbjct: 286 ALTGESIPVERATGDKVPAGATSVDRLVTLEVLSEPGASAIDRILKLIEEAEERRAPIER 345
Query: 303 FITRFAHYYTPAVVGIATLIATVPPLVFKESFTSWVYRALVILVISCPCALVLSIPLGYF 362
FI RF+ YTPA++ +A L+ VPPL+F S+ W+Y+ L +L+I CPCALV+S P
Sbjct: 346 FIDRFSRIYTPAIMAVALLVTLVPPLLFAASWQEWIYKGLTLLLIGCPCALVISTPAAIT 405
Query: 363 GGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRF 422
G+ AA+ G LIKG L+ L + VAFDKTGTLT G +VT I G +E E+L
Sbjct: 406 SGLAAAARRGALIKGGAALEQLGRVTQVAFDKTGTLTVGKPRVTAIHPATGISESELLTL 465
Query: 423 AALAEAHSNHPIAKAI-REAYGKEINEAEITEYEEIAGHGVRARIDSVEVMV---GNDKL 478
AA E + HP+A+AI REA E+ + G G+ A+++ V++ G
Sbjct: 466 AAAVEQGATHPLAQAIVREAQVAELAIPTAESQRALVGSGIEAQVNGERVLICAAGKHPA 525
Query: 479 LHRSNIEHDTCKVKGTIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTG 538
+ + ++ T+ VV + G I + D ++ DA A+ EL LGV+ V++ TG
Sbjct: 526 DAFTGLINELESAGQTVVLVVRNDDVLGVIALQDTLRADAATAISELNALGVKGVIL-TG 584
Query: 539 DSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARAD 598
D+ A IA +LGL+ F A LLPEDKVK + +L + + L VGDGINDAP + A
Sbjct: 585 DNPRAAAAIAGELGLE-FKAGLLPEDKVKAVTELNQ---HAPLAMVGDGINDAPAMKAAA 640
Query: 599 VGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGL 658
+G+AMG+ G+D A+ETAD + + L + I++AR T + +NI ALG+K F+
Sbjct: 641 IGIAMGS-GTDVALETADAALTHNHLRGLVQMIELARATHANIRQNITIALGLKGIFLVT 699
Query: 659 GIFGKATMWEAVFADVGVALIAVFNAMRVLR 689
+ G +W AV AD G ++ NA+R+LR
Sbjct: 700 TLLGMTGLWLAVLADTGATVLVTANALRLLR 730
>emb|CAA04762.1| (AJ001437) putative P-type cation-translocating membrane ATPase
[Proteus mirabilis]
Length = 692
Score = 402 bits (1021), Expect = e-111
Identities = 240/692 (34%), Positives = 392/692 (55%), Gaps = 22/692 (3%)
Query: 11 LDCASCAYEIEEALRKE-GFKFAVVNFATKEAIIEGDIEK-AKEVIKKVEPDVEVVEEVH 68
+DC +CA +IE A+ K G K A + FAT++ +++ DI +K ++ +
Sbjct: 1 MDCPTCAQKIETAVLKVVGVKQAKILFATEKLVVDADIRTDVISAVKSAGFELFDISSAG 60
Query: 69 IHDHAHGEFEKRTIYFIGISLVLFTIGILMRYYYAIDNTLVFGLFLASYLISGWKVLKSA 128
A K + + I I +L I + ID F+A+ LI + ++K
Sbjct: 61 SQPPAKQSLLKESSFVI-ILAILMAISWGAEF---IDPQAGRAAFIATTLIGLFPIVKKL 116
Query: 129 IVNSLNGNVFDENFLIAVATIGAFLIKEYPEGVAVMLFYVIGEFLQDMAVDKSRRSIKAL 188
+ +G F L++VA IGA I E V+L ++IGE L+ A ++RR + AL
Sbjct: 117 LRLIRSGTPFAIETLMSVAAIGALFINATEEAAMVILLFMIGEMLESYAAGRARRGVSAL 176
Query: 189 LALKAEYANLVRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGES 248
+AL E A ++++G V +L+ GDII + PG +P D +I +S D SALTGES
Sbjct: 177 MALVPEEAVVIKEGKKQTVPVAQLRPGDIIEIAPGRALPTDAELITAFASFDESALTGES 236
Query: 249 MPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFA 308
+P +G+++ +G +++ ++++V E ++ + RIL+L+E A RKA E+F+ RF+
Sbjct: 237 VPVERLQGEKVAAGCLSVDRSVQMKVVSEQGQNAIDRILQLIEEAEERKAPIERFVDRFS 296
Query: 309 HYYTPAVVGIATLIATVPPLVFKESFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRA 368
YYTP ++ + L+ +PPL+F + + +W YR L +L+I CPCALV+S P + A
Sbjct: 297 RYYTPLIMLFSALVIIIPPLLFAQPWETWFYRGLTLLLIGCPCALVISTPAAITSALAAA 356
Query: 369 AKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEA 428
K G LIKG L+ L + VA DKTGTLT+G +VT + GF E+E+L A+ E
Sbjct: 357 TKRGALIKGGAALEQLGTVNTVALDKTGTLTEGKPQVTDVIANVGFNEKELLMLASSVEV 416
Query: 429 HSNHPIAKA-IREAYGKEINEAEITEYEEIAGHGVRARIDSVEVMVG-----NDKLLHRS 482
S+HP+AKA I +A ++I+ E + +AG G+ +++ ++V ++ + +
Sbjct: 417 GSHHPLAKAIINKAQEQQIDVVEADNRKALAGKGIEGYLNNQHILVSAPTQLSETIPLSA 476
Query: 483 NIEHDTCKVKG---TIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKV--VMVT 537
+ +++ T+ V+ + Q+ G I + D ++ DA ++KE K L + VM+T
Sbjct: 477 QWQQQVARLEDEGKTVVVVLKEDQFIGVIAMQDTLRNDAIESMKEKKVLKSMNINAVMLT 536
Query: 538 GDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARA 597
GD+ A IA++LG+D F A LLPEDKV + ++ + + VGDGINDAP + A
Sbjct: 537 GDNPRAAAAIAQKLGMD-FRAGLLPEDKVTSVMEISQTHNT---MMVGDGINDAPAMKAA 592
Query: 598 DVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIG 657
+GVAMG+ G+D A+ETAD + ++ + LP+ IQ++R T++I+ ENI ALG+K F+
Sbjct: 593 TIGVAMGS-GTDVALETADAALTHNRLTGLPEIIQLSRATRKIIRENITIALGLKAIFLV 651
Query: 658 LGIFGKATMWEAVFADVGVALIAVFNAMRVLR 689
+FG +W AV AD G + NA+R+L+
Sbjct: 652 TSLFGITGLWVAVLADSGATALVTANAVRLLK 683
>gb|AAG18768.1| (AE004981) zinc-transporting ATPase; ZntA [Halobacterium sp. NRC-1]
Length = 757
Score = 396 bits (1006), Expect = e-109
Identities = 251/749 (33%), Positives = 389/749 (51%), Gaps = 74/749 (9%)
Query: 5 KLKLEGLDCASCAYEIEEALRKEGFKFAVVNFATKEAIIEGDIEKAKEVIKKVEPDVEVV 64
+L + G+DC+SCA + +AL A V A +E G + + PDV
Sbjct: 16 RLDVPGMDCSSCAGSVADALDAT----AGVT-AHEEQPTTGSVVVTLDESTATTPDVVAA 70
Query: 65 EEVHIHDHAHGEFEKRT----------IYFIGISLVLFTIGILMRYYYAIDNTLVFGL-- 112
E +D + ++ T + V G+ +R++ D +V G+
Sbjct: 71 VEAAGYDVTGTDGDRDTSRADVWTSPRALQTAVGGVFLLAGLALRFFVG-DANVVLGVVA 129
Query: 113 ----------FLASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKE------ 156
FL + G+K L++ S D +FL+++A +GA
Sbjct: 130 GTSLHAADVAFLVAVAAGGFKTLRNG-ARSARDRRMDIDFLMSIAILGALTASFAFGKPL 188
Query: 157 YPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVR-DGTVVKVKPEELKVG 215
Y E + + + I E L+ A+D++R+S++ L+AL + A ++ DGT V + + +G
Sbjct: 189 YFEAATLAVLFSIAELLEGYAMDRARQSLRELMALSPDEATIIDPDGTETTVPADTVSIG 248
Query: 216 DIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVT 275
D + V+PGEK+P DGV+++G S+VD S +TGES+P + + GDE+ +G +N TG L+V VT
Sbjct: 249 DRVAVRPGEKIPADGVVVDGDSAVDQSPVTGESVPESKQPGDEVYAGTVNETGYLEVEVT 308
Query: 276 RELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKESFT 335
+ T+SRI+ELVE+A + + E+F+ RFA YTPAVV +A L P V S+
Sbjct: 309 AAPGDDTLSRIVELVEDAQSNQTDREQFVERFAAKYTPAVVALAVLTTLGSPFVLGVSWP 368
Query: 336 SWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKT 395
+ V L +LV++CPCA V+S P+ I AA G+L+KG +L+A+ D +VAFDKT
Sbjct: 369 TAVVHGLTLLVLACPCAFVISTPVSVVSAITSAANHGVLVKGGTHLEAMADVDVVAFDKT 428
Query: 396 GTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKE-INEAEITEY 454
GTLT G VT + NG E ++L A EA S HPIA AI +A + ++ +T++
Sbjct: 429 GTLTAGDLAVTDVRGLNGHRERDVLACARGLEARSEHPIADAIVDAADEAGVDAPSVTDF 488
Query: 455 EEIAGHGVRARIDSVEVMVGNDKLL--HRSNIEHDTCKVKGTIAHVVIDGQYA------- 505
+ + G GVRA +D G L H ++ H G + D ++A
Sbjct: 489 DSVTGQGVRATLDGQPHFAGKPALFEEHGVDLSHVHATTDGGLRAAQPDCEHADCLDLRA 548
Query: 506 -----------------------GYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRD 542
G I + D ++ A V L+ GV + VM+TGD+
Sbjct: 549 DTIPDLQAAGKTVVLVGTADALLGVIAVGDTVRAGAADTVSRLREHGVARTVMLTGDNER 608
Query: 543 VAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVA 602
A + ++G+D YA+ LP +K ++ L+ E +G + VGDGINDAP LA A VG+A
Sbjct: 609 TARAVGDEVGVDAVYADCLPAEKASVVADLQDE--HGDVAMVGDGINDAPALAAATVGIA 666
Query: 603 MGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGLGI-F 661
MGA G+D AIETADV ++ D + LP ++A T ++ +NI +LG+K A + +G+ F
Sbjct: 667 MGAAGTDTAIETADVALLGDAITTLPYLYELAGDTNTVIRQNIWASLGLKAA-LAVGVPF 725
Query: 662 GKATMWEAVFA-DVGVALIAVFNAMRVLR 689
G +W AV A D G+ L NA+R+ R
Sbjct: 726 GLVPIWLAVLAGDAGMTLGVTGNALRLGR 754
>pir||C83185 probable metal-transporting P-type ATPase PA3690 [imported] -
Pseudomonas aeruginosa (strain PAO1)
>gi|9949854|gb|AAG07078.1|AE004788_8 (AE004788) probable
metal-transporting P-type ATPase [Pseudomonas
aeruginosa]
Length = 740
Score = 395 bits (1004), Expect = e-109
Identities = 227/605 (37%), Positives = 360/605 (58%), Gaps = 19/605 (3%)
Query: 97 LMRYYYAIDNTLVFGLFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKE 156
++ ++ + +V GL L + L +G + + N N+ + N L+++A GA LI +
Sbjct: 140 IVEWFGLAPDWVVAGLALLAILGAGLPTYRKGWIALKNRNL-NINALMSIAVTGAVLIGQ 198
Query: 157 YPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGD 216
+PE V + + I E ++ ++D++R +I+ LL L E A ++ G ++ +++++
Sbjct: 199 WPEAAMVSVLFAIAELIEAKSLDRARNAIRGLLQLAPEQATVLVGGEWKELPAKQVELEA 258
Query: 217 IIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTR 276
+ VKPGE++ +DG + G SSV+ + +TGES+P + G+ + +G IN G L+ RVTR
Sbjct: 259 TVRVKPGERIALDGEVTSGRSSVNQAPITGESLPVEKEVGEPVFAGSINGEGALEYRVTR 318
Query: 277 ELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKESFTS 336
+ST++RI+ VE A +A T++F+ FA YTP V IA A +PPL+F ++
Sbjct: 319 RADDSTLARIIHAVEEAQGSRAPTQRFVDSFARVYTPVVFLIALATAVLPPLLFGGAWLD 378
Query: 337 WVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTG 396
W+YRALV+LVI+CPCALV+S P+ G+ AA+ GILIKG +L+ + S VA DKTG
Sbjct: 379 WIYRALVLLVIACPCALVISTPVTIVSGLSAAARLGILIKGGVFLELGRKLSWVALDKTG 438
Query: 397 TLTKGVFKVT---KIETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKE-INEAEIT 452
T+T G + T I +G T+ +L AA A S+HP+++A+ A ++ + +
Sbjct: 439 TITHGKPQQTDYLPIAEADG-TDARLL--AASLAARSDHPVSRAVANAAEEDGLALGVVE 495
Query: 453 EYEEIAGHGVRARIDSVEVMVGNDKLLHRSNI-------EHDTCKVKGTIAHVVIDGQ-Y 504
+ + G GV RID V +GN +L+ + D + +G + D Q
Sbjct: 496 DLAALPGRGVSGRIDGVLYHLGNHRLVEELGLCSPALEERLDALERQGKTVIALCDPQRV 555
Query: 505 AGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPED 564
++D +K+ + A+ EL L V K +M+TGD+ A IA Q+G+D LLPED
Sbjct: 556 RALFAVADGVKDSSREAIHELHALDV-KTLMLTGDNPHTAAAIAAQVGIDAARGNLLPED 614
Query: 565 KVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKP 624
K++ +E ++ ++ VGDGINDAP LARAD+G AMGA G+D AIETA V +MDD
Sbjct: 615 KLREVE--ARQADGSRVGMVGDGINDAPALARADIGFAMGAAGTDTAIETAGVALMDDDL 672
Query: 625 SKLPKAIQIARKTQRIVWENIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIAVFNA 684
KLP+ ++++R T I+ +NI ALG+K F+ L + G+ T+W AVFAD+G +L+ VFN
Sbjct: 673 RKLPQFVRLSRTTHAILVQNITLALGIKAVFLALTLAGEGTLWMAVFADMGASLLVVFNG 732
Query: 685 MRVLR 689
+R+LR
Sbjct: 733 LRLLR 737
>pir||E69153 cadmium efflux ATPase - Methanobacterium thermoautotrophicum
(strain Delta H) >gi|2621474|gb|AAB84917.1| (AE000825)
cadmium efflux ATPase [Methanobacterium
thermoautotrophicum]
Length = 605
Score = 388 bits (986), Expect = e-106
Identities = 227/609 (37%), Positives = 355/609 (58%), Gaps = 22/609 (3%)
Query: 82 IYFIGISLVLFTIGILMRYYYAIDNTLVFGLFLASYLISGWKVLKSAIVNSLNGNVFDEN 141
I + S L GIL+ ++ + L +A+ + +G+++ +A+ + L G+ F +
Sbjct: 17 ILVMAASAALLAAGILLDLQGSM---ISVPLLIAAVVAAGYRIFPAAVRSVLRGH-FTVH 72
Query: 142 FLIAVATIGAFLIKEYPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRD 201
LI +A IGA + +Y E V + Y I E+L++ A +S RS+++L+ L+ A ++
Sbjct: 73 VLILIAVIGAIALGDYTEAALVTVLYHIAEYLEEYAHRRSHRSVESLIKLRPRTARVLDG 132
Query: 202 GTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILS 261
G + + E+++ G I +KPGE VP+DG + GTS VD S++TGES+P TV EGD++ +
Sbjct: 133 GERI-MGVEDVEEGSTIGIKPGETVPLDGTVKSGTSQVDQSSITGESLPVTVGEGDQVFA 191
Query: 262 GMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATL 321
G NL G L+V+VTR + ++ ++E V ++ R+++ E+FI RFA YTP V G+A L
Sbjct: 192 GTQNLDGYLEVKVTRTSEATVLAGVIETVRRSALRRSRRERFIERFASIYTPTVTGLAAL 251
Query: 322 IATVPPLVFKESFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYL 381
A +P L + T W+YRALV+LVISCPCAL++S P+ G+ AA GILIKGS +L
Sbjct: 252 TALIPVLTGGDPLT-WIYRALVLLVISCPCALLISTPVAMVSGMTAAAGRGILIKGSEFL 310
Query: 382 DALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIREA 441
+ + + FDKTGTLT+G +V +E +EILR AA E S HPIA+AI +
Sbjct: 311 EKMASTGCIIFDKTGTLTEGRPEVIAVEPEE--RRDEILRIAASLERKSGHPIAEAIVNS 368
Query: 442 YGKEINEAEITEYEEIAGHGVRARIDSVEVMVGNDKLLHRSNIEHDTCKVKGTIAHVVID 501
Y ++T++ I G GV I+ V +G+ + N + +GT +
Sbjct: 369 YSG--RTVDVTDFRSIPGRGVSGYIEGVRYTLGSPE-TGGGNPD------RGTEVQLTGP 419
Query: 502 GQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELL 561
G I + D I++ A L+ G+ +M+TGD+ D A +A ++G + + LL
Sbjct: 420 EGVIGVIRLRDSIRKSAGRITGRLRERGI-GTLMLTGDTEDSAAAVAAEIGAERYRGGLL 478
Query: 562 PEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMD 621
PEDK++II +L K V VGDG+NDAP LA ADVG+AMG GSD AIETAD+ +++
Sbjct: 479 PEDKMRIIRELSSRK---ITVMVGDGVNDAPALAAADVGIAMGVRGSDVAIETADITLVE 535
Query: 622 DKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGLGIFGKATMWEAV-FADVGVALIA 680
D ++ + I I+R+T I+ N + VKL+ L + G +W AV D+G++L
Sbjct: 536 DDLERIDELIDISRRTMDIIRVNTGLTVAVKLSLAVLSVAGLVPLWVAVAVGDMGLSLFV 595
Query: 681 VFNAMRVLR 689
+ N++ + R
Sbjct: 596 ITNSLLLAR 604
>dbj|BAB04463.1| (AP001509) cadmium-transporting ATPase [Bacillus halodurans]
Length = 637
Score = 381 bits (968), Expect = e-104
Identities = 219/611 (35%), Positives = 357/611 (57%), Gaps = 24/611 (3%)
Query: 95 GILMRYYYAIDNTLVF----GLFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIG 150
G+L+ + ++N + ++LA+Y+I G+ K I ++ + L+ A IG
Sbjct: 35 GLLISIGWVLENQQIIPVAVAVYLAAYVIGGYAKAKEGIEETIANRELNVEMLMIFAAIG 94
Query: 151 AFLIKEYPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPE 210
+ I + EG ++ + + L+ ++KS I AL+ L+ E A VR+G+ ++
Sbjct: 95 SAAIGYWIEGAILIFIFSLSGALETYTMNKSNNEISALMELQPEEALRVRNGSEERIPVS 154
Query: 211 ELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLL 270
+L VGD+I++KPGE+VP DG IIEG +S+D +A+TGES+P + DE+ +G +N+ G +
Sbjct: 155 QLLVGDVIVIKPGERVPSDGKIIEGQTSLDEAAITGESIPVSKSLHDEVFAGTVNVRGTI 214
Query: 271 KVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVF 330
V +T+ SE+ +I++LV+ A + K+ +++FI RF Y V+ L+ VP F
Sbjct: 215 MVEITKPNSETLFQKIIQLVQTAQSEKSPSQQFIERFEGPYVKTVLVAVGLMMFVPHFAF 274
Query: 331 KESFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIV 390
S+T YRA+++LV++ PCALV SI I A++GIL+KG +L+ L +
Sbjct: 275 GWSWTETFYRAMILLVVASPCALVASIMPATLSAISNGARKGILLKGGVHLENLGQLRAI 334
Query: 391 AFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAI-REAYGKEINEA 449
AFDKTGTLTKG +VT + R+G T+EE+L + E +SNHP+A AI R A ++
Sbjct: 335 AFDKTGTLTKGTPEVTDVIVRDGMTKEELLTYVVSIEKYSNHPLASAIVRHASTCMNDQL 394
Query: 450 EITEYEEIAGHGVRARIDSVEVMVGNDKLLHRSNIEHDTCKVKGTIA-HVVIDGQ----- 503
+ E++AG GV A ++ + +G + + E + KG +A + +G+
Sbjct: 395 KPVNMEDVAGFGVSAYLNGISWKIGKADFVGKVEAE----QFKGGVATRLAEEGKTIVFA 450
Query: 504 -----YAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYA 558
AG I + D++++D A+++L++ G+R +M+TGDS A IAK+ G+D + A
Sbjct: 451 RDEQGIAGVIALKDQVRKDTLAAIQQLQKAGIR-TIMLTGDSEKTAAAIAKESGIDTYVA 509
Query: 559 ELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVV 618
E LPE KV ++KL ++ G + VGDGINDAP LA A VG+AMG G+D A+ETADVV
Sbjct: 510 ECLPETKVDEMKKL--KQAYGTVAMVGDGINDAPALATASVGIAMGE-GTDVALETADVV 566
Query: 619 IMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGLGIFGKATMWEAVFADVGVAL 678
+M + ++ +AIQ+++K RIV +NI+F++ V LA I + V G +
Sbjct: 567 LMKNHLPRIAEAIQLSKKMNRIVKQNIVFSIVVILALIASNFMQFLHLPMGVIGHEGSTI 626
Query: 679 IAVFNAMRVLR 689
+ + N +R+LR
Sbjct: 627 LVILNGLRLLR 637
>pir||G82251 cation transport ATPase, E1-E2 family VC1033 [imported] - Vibrio
cholerae (group O1 strain N16961)
>gi|9655496|gb|AAF94192.1| (AE004184) cation transport
ATPase, E1-E2 family [Vibrio cholerae]
Length = 768
Score = 377 bits (959), Expect = e-103
Identities = 236/707 (33%), Positives = 387/707 (54%), Gaps = 49/707 (6%)
Query: 8 LEGLDCASCAYEIEEALRKEGFKFAV-VNFATKEAIIEGDIEKAKEVIKKVEPDVEVVEE 66
+ G+DC SCA +IE+A+++ G V V FAT++ ++ + +I++ D
Sbjct: 79 IAGMDCPSCAQKIEKAVKQLGDVTQVQVMFATQKLVVGFNQPSTAPLIEQAVRDSGFSLN 138
Query: 67 VHIHDHAHGEFEKRTIY------FIGISLVLFTIGILM------RYYYAIDNTLVFGLFL 114
A K ++ IGI+ L IG L+ R+ Y + T + GLF
Sbjct: 139 PAASSAATPSQSKPPLWQSENARIIGIA-ALMAIGALVNSSEMSRWIYTL--TCLLGLF- 194
Query: 115 ASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEYPEGVAVMLFYVIGEFLQ 174
L W++ KS G+ F L++VA IGA + E E V+L ++IGE L+
Sbjct: 195 -PILQQAWRLAKS-------GSPFSIETLMSVAAIGALYLGETLEAAMVLLLFLIGERLE 246
Query: 175 DMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIE 234
A ++R ++AL+AL E A + G V V +L+ GD+I V PG ++P DG ++
Sbjct: 247 AYAASRARTGVQALMALVPETAIRIEHGERVTVPAAQLQPGDVIEVAPGGRLPADGRLL- 305
Query: 235 GTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENAS 294
+S+D SALTGES+P + G+ + +G + + ++++ +T + E+ + RIL ++E A
Sbjct: 306 AAASLDNSALTGESLPVELTAGERVSAGCVIVDKVVQIEITSKQGENAIDRILHMIEEAE 365
Query: 295 ARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKESFTSWVYRALVILVISCPCALV 354
+RKA E+F+ +F+ +YTP ++ +A + VPPL F + +W+YR L +L+I+CPCALV
Sbjct: 366 SRKAPLERFLDKFSRWYTPLMMLVALAVIVVPPLAFGADWQTWIYRGLALLLIACPCALV 425
Query: 355 LSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGF 414
+S P G+ AA+ G LIKG L+ L +AFDKTGTLT+G +VT + G+
Sbjct: 426 ISTPAAITSGLAAAARRGALIKGGAALEQLGKIETIAFDKTGTLTEGKPQVTDLIPLQGW 485
Query: 415 TEEEILRFAALAEAHSNHPIAKA-IREAYGKEINEAEITEYEEIAGHGVRARIDSVEVMV 473
+L AA E S+HP+A + + +A +++ + E + G G+ +ID V+
Sbjct: 486 DSATLLARAAAIEMGSHHPLATSLVAKAQAEQLTIPQAQERTALVGRGISGQIDGVQY-- 543
Query: 474 GNDKLLHRSNIEHDTCKV-----------KGTIAHVVIDGQYAGYIVISDEIKEDAHLAV 522
+LL + +E V T+ ++ G I D ++ DA AV
Sbjct: 544 ---RLLAPNRVETKLPDVVKQHVEMLEAESKTVVVMLASDAVVGVIAWQDTLRSDARQAV 600
Query: 523 KELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLV 582
L +LG+ +M+TGD+ A +++QL +D F A LLP+DKV I++L + + ++
Sbjct: 601 AALHQLGI-NALMLTGDNERSAAAMSQQLNMD-FRAGLLPQDKVGYIQQLAQHQ---RVA 655
Query: 583 FVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVW 642
VGDGINDAP + A +G+AMG G+D A+ETAD + ++ +LP I+++R T I+
Sbjct: 656 MVGDGINDAPAMKEASIGIAMGG-GTDVALETADAALTHNRLIELPGMIELSRATLAIIR 714
Query: 643 ENIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIAVFNAMRVLR 689
+N++ ALG+K F+ + G +W AV AD G + NA+R+L+
Sbjct: 715 QNVVLALGLKAVFLVTSLLGITGLWMAVLADSGATALVTLNALRLLK 761
>pir||S77012 cadmium-transporting ATPase (EC 3.6.1.-) cadA-1 - Synechocystis sp.
(strain PCC 6803) >gi|1001823|dbj|BAA10704.1| (D64005)
cadmium-transporting ATPase [Synechocystis sp.]
Length = 642
Score = 377 bits (957), Expect = e-103
Identities = 215/601 (35%), Positives = 350/601 (57%), Gaps = 24/601 (3%)
Query: 108 LVFGLFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLI----KEYP---EG 160
+ F + A+Y+I G+ + + FD + L+ VA +GA + +EY +G
Sbjct: 46 IAFFVLTAAYVIGGFDNAREGLTTLFEEKEFDVDLLMIVAALGAAGLGLWRREYTLIVDG 105
Query: 161 VAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIV 220
++L + I L+ A+ ++ RSI+ L++L A+ A ++R+G + ELK+GD ++V
Sbjct: 106 AVLILIFAISGALEGYAMQRTERSIQGLMSLTADVARVLRNGQEQTIPISELKMGDQVLV 165
Query: 221 KPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSE 280
KPGE VP DG++IEG S+++ +++TGESMP GDE+ +G IN G+L++++ +
Sbjct: 166 KPGELVPTDGLVIEGFSTLNQASITGESMPVEKAIGDEVFAGTINGNGVLRLKIHQPPES 225
Query: 281 STVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKESFTSWVYR 340
S + R++ LV+ A +++FI RF Y +V L+ T+PP + S+ +YR
Sbjct: 226 SLIQRVIRLVQQAQTEAPPSQQFIERFECGYAKVIVIAGLLLGTLPPFLLGWSWEETIYR 285
Query: 341 ALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTK 400
AL+ LV++ PCAL+ SI GI A++GIL K L+ + ++AFDKTGTLT
Sbjct: 286 ALIFLVVASPCALMASIMPALLSGIANGARQGILFKNGAQLERIGRVRVIAFDKTGTLTT 345
Query: 401 GVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKEINEAEIT--EYEEIA 458
G +V I T +++L+ AA E+ S HPI +AI + + ++ N+A T + A
Sbjct: 346 GKPEVVNILATQPST-DKLLQIAAALESLSEHPIGEAIAD-FTRQQNQAWATARNVQAQA 403
Query: 459 GHGVRARIDSVEVMVGNDKLLHRSNIEH---------DTCKVKG-TIAHVVIDGQYAGYI 508
G G+ I+ + +VG + ++ + H + +G T+ V G+ G I
Sbjct: 404 GQGIIGDIEGQQAIVGK-AVFVQAQVNHVATNLIEQSQQWEAEGKTVVWVAYAGEILGLI 462
Query: 509 VISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKI 568
++D ++ A A+ LKRLG+ ++VM+TGD+ A IA+Q+G++ YAELLPEDKV +
Sbjct: 463 AVADTVRPTAAQAIARLKRLGIERIVMLTGDNSRTAHSIAQQVGVNQVYAELLPEDKVDV 522
Query: 569 IEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLP 628
I +L+K+ + + VGDGINDAP LA+A VG+AMGA GSD A+ETAD+V+M D+ +L
Sbjct: 523 IRQLQKQYQS--VAMVGDGINDAPALAQASVGIAMGAAGSDVALETADIVLMADRLERLE 580
Query: 629 KAIQIARKTQRIVWENIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIAVFNAMRVL 688
AI++ R+ Q +V +NI+FALG + + G T+ V G +I + +R+L
Sbjct: 581 HAIRLGRRAQGVVKQNIVFALGFVMILLIANFAGNITLPFGVLGHEGSTVIVTLSGLRLL 640
Query: 689 R 689
R
Sbjct: 641 R 641
>pir||T08987 probable cadmium-transporting ATPase (EC 3.6.1.-) F6G3.140 -
Arabidopsis thaliana >gi|4938487|emb|CAB43846.1|
(AL078464) cadmium-transporting ATPase-like protein
[Arabidopsis thaliana] >gi|7269911|emb|CAB81004.1|
(AL161576) cadmium-transporting ATPase-like protein
[Arabidopsis thaliana]
Length = 951
Score = 368 bits (935), Expect = e-100
Identities = 210/584 (35%), Positives = 342/584 (57%), Gaps = 20/584 (3%)
Query: 118 LISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFL-IKEYPEGVAVMLFYVIGEFLQDM 176
+++G + + V SL D N L+ V T+GA + +++Y E V+ + I E+LQ
Sbjct: 118 VVAGIYPILAKAVASLARFRIDINILVVV-TVGATIGMQDYTEAAVVVFLFTIAEWLQSR 176
Query: 177 AVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGT 236
A K+ +++L++L + A + G V+V +ELK +I VK GE +P+DGV+++G
Sbjct: 177 ASYKASAVMQSLMSLAPQKAVIAETGEEVEV--DELKTNTVIAVKAGETIPIDGVVVDGN 234
Query: 237 SSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASAR 296
VD LTGE+ P + + +G INL G + V T + V+++ +LVE A
Sbjct: 235 CEVDEKTLTGEAFPVPKLKDSTVWAGTINLNGYITVNTTALAEDCVVAKMAKLVEEAQNS 294
Query: 297 KAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKESFTSWVYRALVILVISCPCALVLS 356
K +T++FI + + YYTPA++ I+ +P + + WV+ ALV+LV +CPC L+LS
Sbjct: 295 KTETQRFIDKCSKYYTPAIILISICFVAIPFALKVHNLKHWVHLALVVLVSACPCGLILS 354
Query: 357 IPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIET-RNGFT 415
P+ F + +AA G+LIKG++YL+ L IVAFDKTGT+T+G F V ++ +
Sbjct: 355 TPVATFCALTKAATSGLLIKGADYLETLAKIKIVAFDKTGTITRGEFIVMDFQSLSEDIS 414
Query: 416 EEEILRFAALAEAHSNHPIAKAI---REAYGKEINEAEITEYEEIAGHGVRARIDSVEVM 472
+ +L + + E+ S+HP+A A+ + E + +Y+ G G+ +ID EV
Sbjct: 415 LQSLLYWVSSTESKSSHPMAAAVVDYARSVSVEPKPEAVEDYQNFPGEGIYGKIDGKEVY 474
Query: 473 VGNDKLLHRS------NIEHDTCKVKGTIAHVVIDGQYAGYIVISDEIKEDAHLAVKELK 526
+GN ++ R+ +I+ DT K TI +V + AG +SD + A+KELK
Sbjct: 475 IGNKRIASRAGCLSVPDIDVDT-KGGKTIGYVYVGETLAGVFNLSDACRSGVAQAMKELK 533
Query: 527 RLGVRKVVMVTGDSRDVAEEIAKQLG--LDGFYAELLPEDKVKIIEKLEKEKGNGKLVFV 584
LG+ K+ M+TGD+ A +QLG +D AELLPEDK +II++L++E+ G V
Sbjct: 534 SLGI-KIAMLTGDNHAAAMHAQEQLGNAMDIVRAELLPEDKSEIIKQLKREE--GPTAMV 590
Query: 585 GDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWEN 644
GDG+NDAP LA AD+G++MG GS A ET ++++M + ++P+AI++A++ +R V EN
Sbjct: 591 GDGLNDAPALATADIGISMGVSGSALATETGNIILMSNDIRRIPQAIKLAKRAKRKVVEN 650
Query: 645 IIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIAVFNAMRVL 688
++ ++ +K A + L G +W AV ADVG L+ + N+M +L
Sbjct: 651 VVISITMKGAILALAFAGHPLIWAAVLADVGTCLLVILNSMLLL 694
>gb|AAD12041.1| (AC002392) putative cadmium-transporting ATPase [Arabidopsis
thaliana]
Length = 1172
Score = 367 bits (933), Expect = e-100
Identities = 196/564 (34%), Positives = 330/564 (57%), Gaps = 21/564 (3%)
Query: 139 DENFLIAVATIGAFLIKEYPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANL 198
D N L+ + I ++++ E AV+ + I ++L+ A K+ +++L++L + A +
Sbjct: 149 DINILVIITVIATLAMQDFMEAAAVVFLFTISDWLETRASYKATSVMQSLMSLAPQKAII 208
Query: 199 VRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDE 258
G V+V +E+KV ++ VK GE +P+DG++++G VD LTGE+ P +
Sbjct: 209 AETGEEVEV--DEVKVDTVVAVKAGETIPIDGIVVDGNCEVDEKTLTGEAFPVPKQRDST 266
Query: 259 ILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGI 318
+ +G INL G + V+ T + V+++ +LVE A + K K+++ I + + YYTPA++ +
Sbjct: 267 VWAGTINLNGYICVKTTSLAGDCVVAKMAKLVEEAQSSKTKSQRLIDKCSQYYTPAIILV 326
Query: 319 ATLIATVPPLVFKESFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGS 378
+ +A VP ++ + W + ALV+LV CPC L+LS P+ F + +AA G+LIK +
Sbjct: 327 SACVAIVPVIMKVHNLKHWFHLALVVLVSGCPCGLILSTPVATFCALTKAATSGLLIKSA 386
Query: 379 NYLDALKDASIVAFDKTGTLTKGVFKVTKIET-RNGFTEEEILRFAALAEAHSNHPIAKA 437
+YLD L IVAFDKTGT+T+G F V ++ +L + + E+ S+HP+A
Sbjct: 387 DYLDTLSKIKIVAFDKTGTITRGEFIVIDFKSLSRDINLRSLLYWVSSVESKSSHPMAAT 446
Query: 438 IREAYGKEIN----EAEITEYEEIAGHGVRARIDSVEVMVGNDKLLHRS------NIEHD 487
I + Y K ++ E+ +Y+ G G+ +ID ++ +GN K+ R+ IE D
Sbjct: 447 IVD-YAKSVSVEPRPEEVEDYQNFPGEGIYGKIDGNDIFIGNKKIASRAGCSTVPEIEVD 505
Query: 488 TCKVKGTIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEI 547
T K T+ +V + + AG+ +SD + A+ ELK LG+ K M+TGD++ A
Sbjct: 506 T-KGGKTVGYVYVGERLAGFFNLSDACRSGVSQAMAELKSLGI-KTAMLTGDNQAAAMHA 563
Query: 548 AKQLG--LDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGA 605
+QLG LD + +LLPEDK +II++ +KE G VGDG+NDAP LA AD+G++MG
Sbjct: 564 QEQLGNVLDVVHGDLLPEDKSRIIQEFKKE---GPTAMVGDGVNDAPALATADIGISMGI 620
Query: 606 LGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGLGIFGKAT 665
GS A +T ++++M + ++P+A+++AR+ +R V EN+ ++ +K + L G
Sbjct: 621 SGSALATQTGNIILMSNDIRRIPQAVKLARRARRKVVENVCLSIILKAGILALAFAGHPL 680
Query: 666 MWEAVFADVGVALIAVFNAMRVLR 689
+W AV DVG L+ +FN+M +LR
Sbjct: 681 IWAAVLVDVGTCLLVIFNSMLLLR 704
>pir||F69869 heavy metal-transporting ATPase homolog ykvW - Bacillus subtilis
>gi|2633756|emb|CAB13258.1| (Z99111) similar to heavy
metal-transporting ATPase [Bacillus subtilis]
Length = 637
Score = 367 bits (932), Expect = e-100
Identities = 213/586 (36%), Positives = 325/586 (55%), Gaps = 12/586 (2%)
Query: 112 LFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEYPEGVAVMLFYVIGE 171
LFL +++I G+ K I +L + L+ A IG+ LI + EG ++ + +
Sbjct: 56 LFLLAFVIGGFAKAKEGIEETLESKTLNVELLMIFAAIGSALIGYWAEGAILIFIFSLSG 115
Query: 172 FLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGV 231
L+ ++KS R + +L+ L+ E A L+ +G +V +L+ GD+I++KPGE+V DG+
Sbjct: 116 ALETYTMNKSSRDLTSLMQLEPEEATLMVNGETKRVPVSDLQAGDMIVIKPGERVAADGI 175
Query: 232 IIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVE 291
I G++S+D SALTGESMP GD + +G +N G L VRVT+ +S +I++LVE
Sbjct: 176 IESGSTSLDESALTGESMPVEKNTGDTVFTGTVNRNGSLTVRVTKANEDSLFRKIIKLVE 235
Query: 292 NASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKESFTSWVYRALVILVISCPC 351
+A + + FI RF + Y V+ L+ VP S++ YRA+V +V++ PC
Sbjct: 236 SAQNSVSPAQAFIERFENAYVKGVLIAVALLLFVPHFALGWSWSETFYRAMVFMVVASPC 295
Query: 352 ALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETR 411
ALV SI I A+ G+L+KGS +L+ L ++AFDKTGT+TKG V I
Sbjct: 296 ALVASIMPAALSLISNGARNGMLVKGSVFLEQLGSVQMIAFDKTGTVTKGQPAVETIRIA 355
Query: 412 NGFTEEEILRFAALAEAHSNHPIAKAIRE-AYGKEINEAEITEYEEIAGHGVRARIDSVE 470
GF+E E+L E S+HP+A+AI A + +N++ EE +G GV A + +
Sbjct: 356 EGFSEAEVLEAVYAIETQSSHPLAQAITAYAESRGVNQSGYISIEETSGFGVMAEVSGAK 415
Query: 471 VMVGNDKLL-------HRSNIEHDTCKVKGTIAHVVIDGQYAGYIVISDEIKEDAHLAVK 523
VG + D + TI V D Q AG I + D+I+ +A ++
Sbjct: 416 WKVGKAGFIGEEMAAQFMKQTASDVIQSGHTIVFVKKDDQIAGCIALKDQIRPEAKEVME 475
Query: 524 ELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVF 583
EL RLG+ K M+TGD D A+ IAK+ G+ AE LP+ KV I++L++E G +
Sbjct: 476 ELNRLGI-KTAMLTGDHEDTAQAIAKEAGMTTVVAECLPDQKVNEIKRLKEEFGT--IAM 532
Query: 584 VGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWE 643
VGDGINDAP L ADVG+AMG G+D A+ETAD+V+M + KL +++RK RI+ +
Sbjct: 533 VGDGINDAPALKAADVGIAMGG-GTDVALETADMVLMKNDLKKLVNMCRLSRKMNRIIKQ 591
Query: 644 NIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIAVFNAMRVLR 689
NI+F+L V I + V G ++ + N +R+L+
Sbjct: 592 NIVFSLAVICLLICANFLQAMELPFGVIGHEGSTILVILNGLRLLK 637
>gi|11498084 cation-transporting ATPase, P-type (pacS) [Archaeoglobus fulgidus]
>gi|7428309|pir||A69309 probable
heavy-metal-transporting ATPase (EC 3.6.1.-) AF0473 -
Archaeoglobus fulgidus >gi|2650152|gb|AAB90763.1|
(AE001071) cation-transporting ATPase, P-type (pacS)
[Archaeoglobus fulgidus]
Length = 804
Score = 359 bits (912), Expect = 5e-98
Identities = 261/723 (36%), Positives = 405/723 (55%), Gaps = 65/723 (8%)
Query: 2 MPRKLKLEGLDCASCAYEIEEALRK-EGFKFAVVNFATKEAIIEGDIEKAK-EVIKKVEP 59
M R +++ G+ CA C IE A+ EG + VN AT+ A I D ++ E IK+V
Sbjct: 16 MERTVRVTGMTCAMCVKSIETAVGSLEGVEEVRVNLATETAFIRFDEKRIDFETIKRVIE 75
Query: 60 DVE---VVEEVHIHDHA-HGEFEKRTIY---FIGISLVLFTIGILMRYYYAIDNTLVFGL 112
D+ V E+ + H KR +Y F G+ L+ I + Y ++ + +
Sbjct: 76 DLGYGVVDEQAAVSAEVEHLSRMKRKLYVAAFAGVLLLFLAHFISLPY----EDFVQLLI 131
Query: 113 FLASYLISGWKVLKSAIV----NSLNGNVF-----DENFLIAVATIGAFLIKEYP---EG 160
L + SG + K+A +LN +V FL +V + L +EY
Sbjct: 132 ALPAIFYSGSSIFKAAFSALRRRTLNMDVMYSMGVGAAFLASVLSTAGVLPREYSFYETS 191
Query: 161 VAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIV 220
V ++ F ++G L+ A ++ +IK L+ L+A+ A ++RDG + V EE+ VGDI+IV
Sbjct: 192 VLLLAFLLLGRTLEARAKSRTGEAIKKLVGLQAKTAVVIRDGKEIAVPVEEVAVGDIVIV 251
Query: 221 KPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSE 280
+PGEK+PVDGV++EG S VD S ++GE +P +GDE+ IN TG+LK+R TR E
Sbjct: 252 RPGEKIPVDGVVVEGESYVDESMISGEPVPVLKSKGDEVFGATINNTGVLKIRATRVGGE 311
Query: 281 STVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIAT------LIATVPPLVFKESF 334
+ +++I++LVE+A K ++ + Y+ P V+ +A PL+F +F
Sbjct: 312 TLLAQIVKLVEDAMGSKPPIQRLADKVVAYFIPTVLLVAISAFIYWYFIAHAPLLF--AF 369
Query: 335 TSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDK 394
T+ + +LV++CPCA L+ P G+G+ A+ GILIK ++ L+ + + V FDK
Sbjct: 370 TT----LIAVLVVACPCAFGLATPTALTVGMGKGAELGILIKNADALEVAEKVTAVIFDK 425
Query: 395 TGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAI-REAYGKEINEAEITE 453
TGTLTKG +VT + NG E E+LR AA+AE S HPIA+AI ++A I E +
Sbjct: 426 TGTLTKGKPEVTDLVPLNG-DERELLRLAAIAERRSEHPIAEAIVKKALEHGIELGEPEK 484
Query: 454 YEEIAGHGVRARIDSVEVMVGNDKLLH------RSNIEHDTCKVKGTIAHVVI---DGQY 504
E IAG GV A ++VGN +L+ + +E K++ VI +G+
Sbjct: 485 VEVIAGEGVVAD----GILVGNKRLMEDFGVAVSNEVELALEKLEREAKTAVIVARNGRV 540
Query: 505 AGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPED 564
G I +SD +KE A AV+ELKR+G+ KV M+TGD+ AE I+++L LD AE+LP
Sbjct: 541 EGIIAVSDTLKESAKPAVQELKRMGI-KVGMITGDNWRSAEAISRELNLDLVIAEVLPHQ 599
Query: 565 KVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKP 624
K + ++KL+ ++ + FVGDGINDAP LA+AD+G+A+G+ GSD A+E+ D+V++ D
Sbjct: 600 KSEEVKKLQAKE---VVAFVGDGINDAPALAQADLGIAVGS-GSDVAVESGDIVLIRDDL 655
Query: 625 SKLPKAIQIARKTQRIVWENIIFALGVKLAFI----GL--GIFGKATMWEAVFADVGVAL 678
+ AIQ++RKT + +NI +AL + I GL IFG ++ FA + +A+
Sbjct: 656 RDVVAAIQLSRKTMSKIKQNIFWALIYNVILIPAAAGLLYPIFG--VVFRPEFAGLAMAM 713
Query: 679 IAV 681
+V
Sbjct: 714 SSV 716
>pir||T00532 probable cadmium-transporting ATPase (EC 3.6.1.-) - Arabidopsis
thaliana
Length = 1001
Score = 359 bits (912), Expect = 5e-98
Identities = 192/549 (34%), Positives = 324/549 (58%), Gaps = 21/549 (3%)
Query: 154 IKEYPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELK 213
++++ E AV+ + I ++L+ A K+ +++L++L + A + G V+V +E+K
Sbjct: 1 MQDFMEAAAVVFLFTISDWLETRASYKATSVMQSLMSLAPQKAIIAETGEEVEV--DEVK 58
Query: 214 VGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVR 273
V ++ VK GE +P+DG++++G VD LTGE+ P + + +G INL G + V+
Sbjct: 59 VDTVVAVKAGETIPIDGIVVDGNCEVDEKTLTGEAFPVPKQRDSTVWAGTINLNGYICVK 118
Query: 274 VTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKES 333
T + V+++ +LVE A + K K+++ I + + YYTPA++ ++ +A VP ++ +
Sbjct: 119 TTSLAGDCVVAKMAKLVEEAQSSKTKSQRLIDKCSQYYTPAIILVSACVAIVPVIMKVHN 178
Query: 334 FTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFD 393
W + ALV+LV CPC L+LS P+ F + +AA G+LIK ++YLD L IVAFD
Sbjct: 179 LKHWFHLALVVLVSGCPCGLILSTPVATFCALTKAATSGLLIKSADYLDTLSKIKIVAFD 238
Query: 394 KTGTLTKGVFKVTKIET-RNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKEIN----E 448
KTGT+T+G F V ++ +L + + E+ S+HP+A I + Y K ++
Sbjct: 239 KTGTITRGEFIVIDFKSLSRDINLRSLLYWVSSVESKSSHPMAATIVD-YAKSVSVEPRP 297
Query: 449 AEITEYEEIAGHGVRARIDSVEVMVGNDKLLHRS------NIEHDTCKVKGTIAHVVIDG 502
E+ +Y+ G G+ +ID ++ +GN K+ R+ IE DT K T+ +V +
Sbjct: 298 EEVEDYQNFPGEGIYGKIDGNDIFIGNKKIASRAGCSTVPEIEVDT-KGGKTVGYVYVGE 356
Query: 503 QYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLG--LDGFYAEL 560
+ AG+ +SD + A+ ELK LG+ K M+TGD++ A +QLG LD + +L
Sbjct: 357 RLAGFFNLSDACRSGVSQAMAELKSLGI-KTAMLTGDNQAAAMHAQEQLGNVLDVVHGDL 415
Query: 561 LPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIM 620
LPEDK +II++ +KE G VGDG+NDAP LA AD+G++MG GS A +T ++++M
Sbjct: 416 LPEDKSRIIQEFKKE---GPTAMVGDGVNDAPALATADIGISMGISGSALATQTGNIILM 472
Query: 621 DDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIA 680
+ ++P+A+++AR+ +R V EN+ ++ +K + L G +W AV DVG L+
Sbjct: 473 SNDIRRIPQAVKLARRARRKVVENVCLSIILKAGILALAFAGHPLIWAAVLVDVGTCLLV 532
Query: 681 VFNAMRVLR 689
+FN+M +LR
Sbjct: 533 IFNSMLLLR 541
>sp|O32220|ATCU_BACSU POTENTIAL COPPER-TRANSPORTING ATPASE >gi|7428307|pir||E70041
probable copper-transporting ATPase (EC 3.6.1.-) yvgX -
Bacillus subtilis >gi|2635863|emb|CAB15355.1| (Z99121)
similar to heavy metal-transporting ATPase [Bacillus
subtilis]
Length = 803
Score = 351 bits (892), Expect = 1e-95
Identities = 235/725 (32%), Positives = 378/725 (51%), Gaps = 50/725 (6%)
Query: 8 LEGLDCASCAYEIEEALRK-EGFKFAVVNFATKEAIIEGDIEKA-----KEVIKKVEPDV 61
+EG+ CA+CA IE+ L K EG A VNFA + +E + ++A KE + K+ +
Sbjct: 80 IEGMTCAACANRIEKRLNKIEGVANAPVNFALETVTVEYNPKEASVSDLKEAVDKLGYKL 139
Query: 62 EVVEEVHIHDHAHGEFE-KRTIYFIGISLVLFTIGILMRYYYA-----------IDNTLV 109
++ E A + E K+T I +++ F + M ++ ++ +
Sbjct: 140 KLKGEQDSEAAAKKKEERKQTARLIFSAVLSFPLLWAMVSHFTFTSFIWVPDIFLNPWMQ 199
Query: 110 FGLFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEYP----------- 158
F L + GW A +L + + L+A+ T A+ Y
Sbjct: 200 FALATPVQFLIGWPFYVGAY-KALRNKSANMDVLVALGTTAAYAYSLYLTFQSIGSHGHT 258
Query: 159 -----EGVAVMLFYVI-GEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEEL 212
E A++L ++ G+ + A +S +IK L+ L+A+ A +VRDG + +E+
Sbjct: 259 DGLYYETSAILLTLILLGKLFETKAKGRSSDAIKKLMKLQAKTATVVRDGQEQIIPIDEV 318
Query: 213 KVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKV 272
V DI+ VKPGE++PVDG ++EG S+VD S +TGES+P GD + +N G LK+
Sbjct: 319 LVNDIVYVKPGERIPVDGEVVEGRSAVDESMITGESLPVDKNPGDSVTGSTVNANGFLKI 378
Query: 273 RVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPL-VFK 331
+ ++ +S I+++VE A KA ++ + + + P V+GIA L + L
Sbjct: 379 KAVNVGKDTALSHIIKIVEEAQGSKAPIQRLADQISGIFVPIVLGIAVLTFLIWYLWAAP 438
Query: 332 ESFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVA 391
F + + + +LVI+CPCAL L+ P G GRAA+ GIL KG +L+ +
Sbjct: 439 GDFAEAISKFIAVLVIACPCALGLATPTSIMAGSGRAAEFGILFKGGEHLEKTHRLDTIV 498
Query: 392 FDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKA-IREAYGKEINEAE 450
DKTGT+T G ++T F E+++L+FAA AE S HP+ +A I K + +
Sbjct: 499 LDKTGTVTNGKPRLTDAIPFGRFEEKDLLQFAAAAETGSEHPLGEAIIAGVKDKGLEIPK 558
Query: 451 ITEYEEIAGHGVRARIDSVEVMVGNDKLLHRSNIEH-------DTCKVKG-TIAHVVIDG 502
+T +E G G+ A ++VG KL+ +EH + + +G T+ V IDG
Sbjct: 559 LTRFEAKVGAGILAEAGGKSILVGTRKLMESEQVEHGALLAQMEELEAEGKTVMLVSIDG 618
Query: 503 QYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLP 562
+ AG + ++D IK+ + AV LK LG+ V+M+TGD+R AE IAK+ G+ AE+LP
Sbjct: 619 EAAGLVAVADTIKDTSRKAVARLKELGL-DVIMMTGDNRRTAEAIAKEAGIANIIAEVLP 677
Query: 563 EDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDD 622
E K I +L+KE + VGDGINDAP LA AD+G+A+G G+D A+ETAD+ ++
Sbjct: 678 EQKAAEIARLQKE--GRQTAMVGDGINDAPALATADIGMAIGT-GTDIAMETADITLIRG 734
Query: 623 KPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIAVF 682
+ + AI+++R T + + +N+ +ALG I + G W A A ++ V
Sbjct: 735 DLNSIADAIRMSRLTMKNIKQNLFWALGYNSLGIPIAALGFLAPWIAGAAMAFSSVSVVL 794
Query: 683 NAMRV 687
NA+R+
Sbjct: 795 NALRL 799
>pir||D72392 cation-transporting ATPase, P-type - Thermotoga maritima (strain
MSB8) >gi|4980818|gb|AAD35405.1|AE001713_9 (AE001713)
cation-transporting ATPase, P-type [Thermotoga maritima]
Length = 726
Score = 346 bits (879), Expect = 4e-94
Identities = 236/718 (32%), Positives = 384/718 (52%), Gaps = 58/718 (8%)
Query: 10 GLDCASCAYEIEEALRK-EGFKFAVVNFATKEAIIEGDIEKAKEVIKKVEPDVEV-VEEV 67
G+ CA+CA +E+AL+K +G KFA VN AT I + E + E IKK +V V
Sbjct: 25 GMTCATCAKTVEKALKKLDGVKFAAVNLATSTGFIVAEKEISFEEIKKAVEEVGYGVTTE 84
Query: 68 HIHDHAHGEFEKRTIYFIGISLVLFTIGILMRYYYAIDNTLVF-------GLFLASYLIS 120
D +E+ I LV + +LM Y+ + F G F+ Y+
Sbjct: 85 SPEDVERKRYEESKRNLILAWLVTAPLALLMIYHMFVSEVPYFTWIEVFAGAFVTFYVGR 144
Query: 121 G-----WKVLKSAIVNSLNGNVFDE--NFLIAVA-TIGAFLIKEYPEGVAVMLFYVIGEF 172
G W L N F +++ A+ ++G ++ G ++ F++ G F
Sbjct: 145 GTIRGAWIALTHKHTNMDTLIFFGAVTSWVTALLDSVGLPVMSFGAIGAMIVAFHITGRF 204
Query: 173 LQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVI 232
++ D++ + IKALL L+A+ A ++ D V + E +K G I++VKPGE++PVDGVI
Sbjct: 205 IESYLRDRASKEIKALLKLQAKEARVITDEGEVMMPIEAVKEGFIVLVKPGERIPVDGVI 264
Query: 233 IEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVEN 292
+EG SS+D S +TGES+P KE DE++ G +N++ +K++VT+ ++ +S++++L++
Sbjct: 265 VEGQSSIDESVVTGESIPVLKKENDEVIGGSLNVSSPIKIKVTKVGEDTFLSQMVKLIQE 324
Query: 293 ASARKAKTEKFITRFAHYYTPAVVGIATLIATV--------PPLVFK------------E 332
A K + R ++ P ++ +A A V P V K +
Sbjct: 325 AQGSKVPIQALADRITMWFVPTIIVLAITSALVWYFNYERFLPFVEKAREIFPWIIQTSD 384
Query: 333 SFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAF 392
T ++ + +VI+CPCAL L+ P+ G G AAK+G+LI+ + + KD +V
Sbjct: 385 PLTFSIFVFVATIVIACPCALGLATPMALVTGTGLAAKKGLLIRNAEAIQTSKDVGVVLT 444
Query: 393 DKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKEINEAEIT 452
DKTGTLT+G KV + E++R A E +SNHP+AKAI E + E+
Sbjct: 445 DKTGTLTEGSPKVV-----DHNLSAELIRIVASIERNSNHPLAKAISEL---SQDVVEVE 496
Query: 453 EYEEIAGHGVRARIDSVEVMVGNDKLLHRSNIEHDTCKVKGTIAHVVIDGQYAGYIVISD 512
EEI G GVRA E VG K L S E + TI V +G+ G++ I D
Sbjct: 497 SVEEIPGEGVRALYGGEEYFVG--KPLDYSKYE-SLLEEGKTIVEVRRNGEVVGFLAIED 553
Query: 513 EIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKL 572
I+ED+ AV+ LK +G+ + VM+TGD+ A +A++LG++ F+A + P +K+ ++
Sbjct: 554 PIREDSPEAVRRLKEMGI-EPVMITGDNEKTARAVARRLGIEKFHAGVKPSEKLDLVRSY 612
Query: 573 EKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQ 632
+ + K+ VGDG+NDA L ADVG+A+G+ G+D AI++AD++I SK+ AI+
Sbjct: 613 QAQ--GKKVAMVGDGMNDAAALKGADVGIAIGS-GTDLAIDSADIIITKGGISKVVDAIE 669
Query: 633 IARKTQRIVWENIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIAV---FNAMRV 687
I+RKT +I+ +N+ +A + I + + G + V A++ +A ++ N+MRV
Sbjct: 670 ISRKTFKIIKQNLFWAFFYNVIAIPMAMMG---LLHPVIAELAMAFSSITVTLNSMRV 724
>pir||G69071 heavy-metal-transporting ATPase (EC 3.6.1.-) MTH1535 -
Methanobacterium thermoautotrophicum (strain Delta H)
>gi|2622654|gb|AAB86009.1| (AE000913) heavy-metal
transporting CPx-type ATPase [Methanobacterium
thermoautotrophicum]
Length = 790
Score = 344 bits (872), Expect = 3e-93
Identities = 236/701 (33%), Positives = 373/701 (52%), Gaps = 43/701 (6%)
Query: 10 GLDCASCAYEIEEALRK-EGFKFAVVNFATKEAIIEGD-----IEKAKEVIKKVEPDVEV 63
G+ CA C +IE ALR EG A VN A ++A I + +E K ++ + V
Sbjct: 78 GMSCAMCVQKIESALRGLEGVSNATVNLAAEKAYISYNPSLTSVEDLKRTVEDLGYTVRG 137
Query: 64 VEEVHIHDHAHGEFEKRTIYFIGISLVLFTIGILMRYYYAIDNTLVFGLFLASYLISGWK 123
+E I + + +R I G+S+ L + L +++ + +SG
Sbjct: 138 LEGEEISEDLKPKI-RRIIVGFGVSVPLMAMMYLGLQPPGGGISMLLVSIIPFIYVSG-P 195
Query: 124 VLKSAIVNSLNGNVFDENFLIAVATIGAFL-------------IKEYPEGVAVMLFYVIG 170
+ + A+ SL D + + ++ AFL Y + + F +G
Sbjct: 196 IFRGAL-RSLRSGTLDMDVMYSMGIGVAFLSSILGTAGILPSDFMFYDTALMLASFLTLG 254
Query: 171 EFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIVKPGEKVPVDG 230
+L+ A K+ +++ L+ L+ + A ++RDG V+V+ E+ VGD +IV+PG++VP DG
Sbjct: 255 RYLEAGARGKTSEAVRRLMELQPDTATVLRDGREVEVRIHEIDVGDEVIVRPGDRVPADG 314
Query: 231 VIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELV 290
++EG+S VD +TGE +P G E+++G IN G+L+ RV R E+ +S I++LV
Sbjct: 315 KVVEGSSYVDEFMITGEPLPALKTPGSEVVAGTINTDGILRFRVERTGDETFLSGIIKLV 374
Query: 291 ENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKESFTSWVYRALVILVISCP 350
+ A A K ++ R Y+ PAV+ +AT LV + + +LV++CP
Sbjct: 375 DEAQASKPPIQRIADRAVSYFIPAVLLVATSAFLFWYLVEGAGLLLSITVLISVLVVACP 434
Query: 351 CALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIET 410
CAL L+ P GIGR A+ GILIK L+ S V FDKTGTLT G +VT +
Sbjct: 435 CALGLATPTAVTAGIGRGAELGILIKKGEALEVSDRISCVIFDKTGTLTLGRPRVTDM-- 492
Query: 411 RNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKE-INEAEITEYEEIAGHGVRARIDSV 469
++L AA E S HPIA A+ E +E ++ E ++ I G G+ +DS
Sbjct: 493 -----VGDVLGLAAALERKSRHPIAAAVTERAEEEGVDVPEAEDFRAIPGMGLEGMVDSH 547
Query: 470 EVMVGNDKLLHRSNI--EH-DTCKVKG---TIAHVVIDGQYAGYIVISDEIKEDAHLAVK 523
V+ GN L+ + I EH D K + T+ V +DG+ G I +SDEIK + AV+
Sbjct: 548 HVLAGNRALMEKYGIPLEHWDPEKFESDGKTVVIVAVDGEVKGIIAVSDEIKPGSARAVR 607
Query: 524 ELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVF 583
EL+R+G+ M+TGD+R AE +A+++G+ AE+LP+DK + +L +E+G G + F
Sbjct: 608 ELERMGI-GTAMITGDNRKTAEAVAREVGIGTVIAEVLPQDKATRVAEL-RERGEG-VAF 664
Query: 584 VGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWE 643
VGDGINDAP LA AD+GVA+G+ G+D A E +VV+M D P +P A+Q+A K + +
Sbjct: 665 VGDGINDAPALAEADLGVAVGS-GTDIAREAGEVVLMGDDPLDVPAALQLAGKVISRIRQ 723
Query: 644 NIIFALGVKLAFIGL---GIFGKATMWEAVFADVGVALIAV 681
NI +A + I L ++ ++ +A + +AL +V
Sbjct: 724 NIFWAFAYNVVLIPLAAGALYPLGIVFRPEYAGLAMALSSV 764
>sp|P77894|CTPV_MYCTU PROBABLE CATION-TRANSPORTING ATPASE V >gi|7436408|pir||G70718
probable cation transport atpase - Mycobacterium
tuberculosis (strain H37RV) >gi|1524193|emb|CAB01983.1|
(Z79700) ctpV [Mycobacterium tuberculosis]
Length = 770
Score = 342 bits (869), Expect = 6e-93
Identities = 219/637 (34%), Positives = 351/637 (54%), Gaps = 47/637 (7%)
Query: 84 FIGISLVLFTIGILMRY-YYAIDNTLVFGLFLASYLISGWKVLKSAI--VNSLNGNVFDE 140
++ + L L +G M + Y L F L ++GW +L+ A+ +L N+
Sbjct: 142 WLALPLGLLALGSSMFFGAYPWAGWLAFAATLPVQFVAGWPILRGAVQQARALTSNM--- 198
Query: 141 NFLIAVATIGAFLIKEYP----------EGVAVMLFYVIGEFLQDMAVDKSRRSIKALLA 190
+ LIA+ T+ AF+ Y ++ F V+G L+ A K+ +I LL
Sbjct: 199 DTLIALGTLTAFVYSTYQLFAGGPLFFDTSALIIAFVVLGRHLEARATGKASEAISKLLE 258
Query: 191 LKAEYANLVRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMP 250
L A+ A L+ DG + V ++++VGD++ V+PGEK+PVDG + +G ++VD S LTGES+P
Sbjct: 259 LGAKEATLLVDGQELLVPVDQVQVGDLVRVRPGEKIPVDGEVTDGRAAVDESMLTGESVP 318
Query: 251 RTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHY 310
GD + +NL GLL VR T +++ +++I+ LVE A KA ++ R +
Sbjct: 319 VEKTAGDRVAGATVNLDGLLTVRATAVGADTALAQIVRLVEQAQGDKAPVQRLADRVSAV 378
Query: 311 YTPAVVGIA-------TLIATVPPLVFKESFTSWVYRALVILVISCPCALVLSIPLGYFG 363
+ PAV+G+A TLIA P + + A+ +L+I+CPCAL L+ P
Sbjct: 379 FVPAVIGVAVATFAGWTLIAANP--------VAGMTAAVAVLIIACPCALGLATPTAIMV 430
Query: 364 GIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFA 423
G GR A+ GIL+KG L+A K V FDKTGTLT+ +VT + +++LR A
Sbjct: 431 GTGRGAELGILVKGGEVLEASKKIDTVVFDKTGTLTRARMRVTDVIAGQRRQPDQVLRLA 490
Query: 424 ALAEAHSNHPIAKAI-REAYGKEINEAEITEYEEIAGHGVRARIDSVEVMVGNDKLLHRS 482
A E+ S HPI AI A+ + + + +AGHGVRA+++ V+VG KL+
Sbjct: 491 AAVESGSEHPIGAAIVAAAHERGLAIPAANAFTAVAGHGVRAQVNGGPVVVGRRKLVDEQ 550
Query: 483 NI---EHDTC-----KVKG-TIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKV 533
++ +H + +G T V DGQ G + ++D +K+DA V L +G+ +V
Sbjct: 551 HLVLPDHLAAAAVEQEERGRTAVFVGQDGQVVGVLAVADTVKDDAADVVGRLHAMGL-QV 609
Query: 534 VMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLV-FVGDGINDAP 592
M+TGD+ A IAKQ+G++ AE+LP+DKV + +L+ + G++V VGDG+NDAP
Sbjct: 610 AMITGDNARTAAAIAKQVGIEKVLAEVLPQDKVAEVRRLQDQ---GRVVAMVGDGVNDAP 666
Query: 593 VLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVK 652
L +AD+G+A+G G+D AIE +D+ +M + + +AI+++R+T R +++N+ +A G
Sbjct: 667 ALVQADLGIAIGT-GTDVAIEASDITLMSGRLDGVVRAIELSRQTLRTIYQNLGWAFGYN 725
Query: 653 LAFIGLGIFGKATMWEAVFADVGVALIAVFNAMRVLR 689
A I L G A A ++ V N++R+ R
Sbjct: 726 TAAIPLAALGALNPVVAGAAMGFSSVSVVTNSLRLRR 762
>sp|Q9X5X3|ATCU_RHIME COPPER-TRANSPORTING ATPASE >gi|4680350|gb|AAD27639.1|AF129004_1
(AF129004) P-type ATPase ActP [Sinorhizobium meliloti]
Length = 827
Score = 342 bits (867), Expect = 1e-92
Identities = 240/758 (31%), Positives = 389/758 (50%), Gaps = 88/758 (11%)
Query: 1 MMPRKLKLEGLDCASCAYEIEEALRK-EGFKFAVVNFATKEAIIE------------GDI 47
++ ++++EG+ CASC +E+AL+ G A VN AT++A + +
Sbjct: 81 IVTEEIQIEGMTCASCVSRVEKALKAVPGVADASVNLATEKATVRLVSGSAEISALAAAV 140
Query: 48 EKAKEVIKKVEPDVEVVEEVHIHDHAHGEF--------------------EKRTIYFIGI 87
+ A I+K P + E+V DH E E + + G+
Sbjct: 141 KGAGYGIRKATPAEAMKEDV---DHRTAELRSLKSAVTISSLMTLPLFLLEMGSHFIPGV 197
Query: 88 -SLVLFTIGILMRYY--YAIDNTLVFGLFLASYLISGWKVLKSAIVNSLNGNVFDENFLI 144
++ TIG+ Y +A+ ++FG G + + + N L D N L+
Sbjct: 198 HDFIMGTIGMRNNLYLQFALATLVLFG--------PGLRFFRKGVPNLLRWTP-DMNSLV 248
Query: 145 AVATIGA--------FLIKEYPEGVA---------VMLFYVIGEFLQDMAVDKSRRSIKA 187
+ T A F+ P G A ++ ++G +L+ A ++ ++IK
Sbjct: 249 VLGTTAAWGYSVVTTFVPAILPSGTANVYYEAAAVIVTLILVGRYLESRAKGRTSQAIKR 308
Query: 188 LLALKAEYANLVRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGE 247
L+ L+ + A ++ G V+ + E+ GD+I ++PGEK+PVDG + +G+S VD S +TGE
Sbjct: 309 LVGLQPKTAFVLHSGEFVETEITEVVTGDVIRIRPGEKIPVDGTVTDGSSYVDESMITGE 368
Query: 248 SMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRF 307
+P ++ G IN TG + + T+ S++ +++I+ LVE A K + + R
Sbjct: 369 PVPVQKATDSAVIGGTINKTGSITFKATKVGSDTLLAQIIRLVEAAQGSKLPIQALVDRV 428
Query: 308 AHYYTPAVVGIATLIATVPPLVFKES--FTSWVYRALVILVISCPCALVLSIPLGYFGGI 365
++ P V+ +A L+ V S + + A+ +L+I+CPCA+ L+ P G
Sbjct: 429 TAWFVPVVI-LAALLTFAAWYVLGPSPALSFALVNAVAVLIIACPCAMGLATPTSIMVGT 487
Query: 366 GRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAAL 425
GRAA+ GIL + L +L+DA +VA DKTGTLTKG ++T + GF +E+L A
Sbjct: 488 GRAAELGILFRKGEALQSLRDADVVAVDKTGTLTKGRPELTDLVAAEGFEPDEVLCLVAS 547
Query: 426 AEAHSNHPIAKAI-REAYGKEINEAEITEYEEIAGHGVRARIDSVEVMVGNDKLLHRSNI 484
E S HPIA+AI A + I ++ +E G GV + V+VG D+ L ++ I
Sbjct: 548 LETLSEHPIAEAIVSAAKSRGIATVAVSAFEATPGFGVSGTVSGRRVLVGADRALVKNGI 607
Query: 485 E----HDTCKVKG----TIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMV 536
+ D + G + + IDG+ A + +SD +KE A+K L LG+ KV MV
Sbjct: 608 DITGFADEAERLGSGGKSPLYAAIDGRLAAIVAVSDPVKESTPQAIKSLHALGL-KVAMV 666
Query: 537 TGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLAR 596
TGD+R AE IAK+LG+D AE+LPE KV + KL +G + F+GDGINDAP LA
Sbjct: 667 TGDNRRTAEAIAKKLGIDEVVAEVLPEGKVDAVRKL--RQGGRSVAFIGDGINDAPALAE 724
Query: 597 ADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENII--FALGVKLA 654
ADVG+A+G G+D AIE+ADVV+M + + KA+ +++ T R + +N+ F + L
Sbjct: 725 ADVGIAVGT-GTDIAIESADVVLMSGDLNGVAKALALSKATIRNIKQNLFWAFVYNISLV 783
Query: 655 FIGLGIF--GKATMWEAVFADVGVALIAVF---NAMRV 687
+ G+ T+ +FA +A+ +VF NA+R+
Sbjct: 784 PVAAGVLYPVNGTLLSPIFAAAAMAMSSVFVLGNALRL 821
>dbj|BAB04276.1| (AP001508) copper-transporting ATPase [Bacillus halodurans]
Length = 806
Score = 337 bits (856), Expect = 2e-91
Identities = 224/736 (30%), Positives = 384/736 (51%), Gaps = 70/736 (9%)
Query: 10 GLDCASCAYEIEEAL-RKEGFKFAVVNFATKEAIIE--------GDIEKAKEVIK-KVEP 59
G+ CA+CA IE+ L R EG AVVN A + A +E D+E+A E I ++
Sbjct: 81 GMTCAACANRIEKKLNRLEGVHKAVVNLALETATVEYRPESVSPSDLEQAIEQIGYTLKR 140
Query: 60 DVEVVEEVHIHDHAHGEFEKRTIYFIGISLVLFTIGILMRYYYAIDNTLVFGLFL----- 114
EE + + + ++R ++I L L + ++ ++ + LF+
Sbjct: 141 KTGDAEEGDVRERELQKQKRR--FWISAVLTLPLLWSMVTHFEFTSFIWMPHLFMDPWVQ 198
Query: 115 ------------ASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEY----- 157
A + + +K L+ N + L+A+ T A+ Y
Sbjct: 199 LLLATPVQFYIGAPFYVGAYKALRHKSANM--------DVLVALGTSAAYFYSMYLGYDW 250
Query: 158 ----PEGVAVMLFY----------VIGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGT 203
EG+ L++ V+G++ + A ++ +I+ LL L+A+ A ++R+G
Sbjct: 251 LYGTREGMMPELYFEASAIIITLIVLGKYFEARAKGRTSEAIRKLLGLQAKTARVIREGK 310
Query: 204 VVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGM 263
++ EE+K GD+++VKPGEK+PVDG ++EG S+VD S LTGES+P GD+++
Sbjct: 311 EEQIPLEEVKTGDLLLVKPGEKIPVDGEVVEGYSAVDESMLTGESIPVEKDVGDQVIGAT 370
Query: 264 INLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIA 323
+N G L++R TR ++ +++I+++VE A KA ++ + + + + P VV I+ L
Sbjct: 371 VNHNGSLRIRATRVGKDTALAQIVKVVEEAQGSKADIQRAVDKVSSIFVPVVVAISVLTF 430
Query: 324 TVPPLVFKE-SFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLD 382
V +V + TS + + ILVI+CPCAL L+ P G GR+A+ G+L KG +L+
Sbjct: 431 LVWYMVIDPGNVTSALIPTISILVIACPCALGLATPTSIMAGSGRSAELGVLFKGGEHLE 490
Query: 383 ALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIREAY 442
+ V DKTGT+T+G +T T E+E+ AE S HP+A AI +
Sbjct: 491 HTQRIDTVVLDKTGTVTEGKPSLTDFVTYGSADEKEMATMLHAAERRSEHPLATAIVDGM 550
Query: 443 GK-EINEAEITEYEEIAGHGVRARIDSVEVMVGNDKLLHRSNIEH-------DTCKVKG- 493
+ ++ E + I GHGV A + V+VG KL+ +++ + + +G
Sbjct: 551 KQLGVDRLEADSFSAIPGHGVEAMVAGRNVLVGTRKLMAEHQVDYKEALSSAEAREARGE 610
Query: 494 TIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGL 553
T+ + +DG ++ ++D++K + A++ LK LG+ +VM+TGD+ A +A +G+
Sbjct: 611 TVMFMAVDGILTAHVAVADQLKSSSKKAIERLKALGL-DIVMLTGDNERTARAVANDVGI 669
Query: 554 DGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIE 613
+ AE+LP+DK + I KL+K+ + VGDG+NDAP LA ADVG+A+G+ +D IE
Sbjct: 670 EQVIAEVLPKDKSEQIRKLQKQ--GRTVAMVGDGLNDAPALATADVGMAIGS-ATDIPIE 726
Query: 614 TADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGLGIFGKATMWEAVFAD 673
AD+ ++ D ++ A+ +++KT R + +N+ FA + I + G W A A
Sbjct: 727 AADLTLLGDDLHRVADAVLMSQKTMRNIKQNLFFAFVYNTSAIPIAAAGLLAPWVAGAAM 786
Query: 674 VGVALIAVFNAMRVLR 689
++ V NA+R+ R
Sbjct: 787 AFSSVSVVLNALRLQR 802
>gb|AAB01764.1| (U42410) heavy-metal transporting P-type ATPase [Proteus mirabilis]
Length = 829
Score = 337 bits (856), Expect = 2e-91
Identities = 246/751 (32%), Positives = 391/751 (51%), Gaps = 76/751 (10%)
Query: 5 KLKLEGLDCASCAYEIEEALRK-EGFKFAVVNFATKEAIIEGDIEKAKEVIKKVEPDVEV 63
+L +E + CASC +E+AL + G A VN AT+ A + V+ + +V V
Sbjct: 81 ELAIEEMTCASCVGRVEKALAQIPGVLEATVNLATERA----RVRHLSGVVSITDLEVAV 136
Query: 64 VEE-----------VHIHDHAHGEFEKR-----------TIYFIGISLVLFTIGILMRYY 101
V + D + EK TI+ + + ++ + +
Sbjct: 137 VHAGYKPRRLSDNPANTRDLSEERREKEARSLRRALLIATIFTLPVFVIEMGSHFIPGVH 196
Query: 102 YAIDNTLVFGL-----FLASYLIS---GWKVLKSAIVNSLNGNVFDENFLIAVATIGA-- 151
+ + TL L F+ + ++ G + K I L G D N L++V T+ A
Sbjct: 197 HWVTQTLGQQLNWYIQFVLATIVMFGPGLRFFKKGIPALLRGAP-DMNSLVSVGTVAAYG 255
Query: 152 ------FLIKEYPEGVAVMLF---------YVIGEFLQDMAVDKSRRSIKALLALKAEYA 196
F+ + P G A + F ++G L+ A + ++IK L+ L+A+ A
Sbjct: 256 YSVVSTFIPQVLPAGTANIYFEAAVVIVTLILLGRNLEAKAKGNTSQAIKRLVGLQAKTA 315
Query: 197 NLVRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEG 256
+ R G ++++ +++ +GDI++V+PGEK+PVDG ++EG S VD S +TGE +P + G
Sbjct: 316 RVSRHGEILEIPLDQVMMGDIVVVRPGEKIPVDGEVVEGHSYVDESMITGEPVPVAKEIG 375
Query: 257 DEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVV 316
E++ G IN TG +VT+ + + +++I+ LVE A K + + + ++ PAV+
Sbjct: 376 AEVVGGTINKTGTFSFKVTKVGANTILAQIIRLVEEAQGSKLPIQALVDKVTMWFVPAVM 435
Query: 317 GIATLIATVPPLVF--KESFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGIL 374
I I L F + + T + A+ +L+I+CPCA+ L+ P G GRAA+ GIL
Sbjct: 436 -IGATITFFIWLAFGPEPALTFALINAVAVLIIACPCAMGLATPTSIMVGTGRAAELGIL 494
Query: 375 IKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPI 434
+ L AL+D S+VA DKTGTLTKG ++T + F EIL A E +S HPI
Sbjct: 495 FRKGEALQALRDVSVVALDKTGTLTKGRPELTDLIPAEKFEYNEILSLVASIETYSEHPI 554
Query: 435 AKAIREAYGK-EINEAEITEYEEIAGHGVRARIDSVEVMVGNDKLLHRSNIEHDTCKVKG 493
A++I A + ++ A + +E I G GV A +D V VG D+ + + ++
Sbjct: 555 AQSIVNAANEAKLTLASVDNFEAIPGFGVSATVDGRSVSVGADRFMKQLGLDVSQFASSA 614
Query: 494 --------TIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAE 545
T + IDG+ A I ++D IKE A+K L LG+ KV M+TGD++ A+
Sbjct: 615 QKLGEQGKTPLYTAIDGRLAAIIAVADPIKETTPEAIKALHALGL-KVAMITGDNKATAK 673
Query: 546 EIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGA 605
IAKQLG+D AE+LP+ KV +++L +KG+ K+ FVGDGINDAP LA+ADVG+A+G
Sbjct: 674 AIAKQLGIDEIVAEVLPDGKVAALKQL-SQKGD-KVAFVGDGINDAPALAQADVGLAIGT 731
Query: 606 LGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENII--FALGVKLAFIGLGIFG- 662
G+D AIE ADVV+M + AI +++ T R + +N+ FA L + G+
Sbjct: 732 -GTDVAIEAADVVLMSGDLRGVVDAIALSQATIRNIKQNLFWTFAYNALLIPVAAGMLYP 790
Query: 663 -KATMWEAVFADVGVALIAVF---NAMRVLR 689
+ +FA +AL +VF NA+R+ R
Sbjct: 791 INGMLLSPIFAAAAMALSSVFVLGNALRLKR 821
>sp|Q10866|CTPG_MYCTU PROBABLE CATION-TRANSPORTING ATPASE G >gi|7436406|pir||F70757
probable cation transport ATPase - Mycobacterium
tuberculosis (strain H37RV) >gi|3261588|emb|CAA98411.1|
(Z74025) ctpG [Mycobacterium tuberculosis]
Length = 771
Score = 336 bits (852), Expect = 6e-91
Identities = 208/603 (34%), Positives = 330/603 (54%), Gaps = 14/603 (2%)
Query: 90 VLFTIGILMRYYYAIDNTLVFGLFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATI 149
VL T ++ + Y + +V GL + + + S++ G V L+ +A +
Sbjct: 163 VLLTASLVAAWAYPLW-PVVLGLKALALAVGASTFVPSSLKRLAEGRV-GVGTLMTIAAL 220
Query: 150 GAFLIKEYPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKP 209
GA + E E + + I E L++ A ++RR ++ALL+L + A ++R+GT V
Sbjct: 221 GAVALGELGEAATLAFLFSISEGLEEYATARTRRGLRALLSLVPDQATVLREGTETIVAS 280
Query: 210 EELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGL 269
EL VGD +IVKPGE++ DG+I G +++D SA+TGES+P V GDE+ +G IN G+
Sbjct: 281 TELHVGDQMIVKPGERLATDGIIRAGRTALDVSAITGESVPVEVGPGDEVFAGSINGLGV 340
Query: 270 LKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLV 329
L+V VT + ++++RI+ +VE RK +++ A P+++ A LIA ++
Sbjct: 341 LQVGVTATAANNSLARIVHIVEAEQVRKGASQRLADCIARPLVPSIMIAAALIAGTGSVL 400
Query: 330 FKESFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASI 389
W+ RALV+LV + PCAL +++P+ IG A++ G+LIKG L+ L
Sbjct: 401 GNP--LVWIERALVVLVAAAPCALAIAVPVTVVASIGAASRLGVLIKGGAALETLGTIRA 458
Query: 390 VAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKEINEA 449
VA DKTGTLT V + T NG T EE+L AA EA S HP+A A+ A +
Sbjct: 459 VALDKTGTLTANRPVVIDVATTNGATREEVLAVAAALEARSEHPLAVAVLAATQATTAAS 518
Query: 450 EITEYEEIAGHGVRARIDSVEVMVGNDKLLHRSNI-EHDTCKVKGTIAHVVI--DGQYAG 506
++ + + G G+ R+D V +G L + + +H C + V++ D Q G
Sbjct: 519 DV---QAVPGAGLIGRLDGRVVRLGRPGWLDAAELADHVACMQQAGATAVLVERDQQLLG 575
Query: 507 YIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKV 566
I + DE++ +A V L R G +V M+TGD+ A +A Q G++ +AEL PEDK
Sbjct: 576 AIAVRDELRPEAAEVVAGL-RTGGYQVTMLTGDNHATAAALAAQAGIEQVHAELRPEDKA 634
Query: 567 KIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSK 626
++ +L + VGDG+NDAP LA AD+G+AMGA+G+D AIETADV +M
Sbjct: 635 HLVAQL---RARQPTAMVGDGVNDAPALAAADLGIAMGAMGTDVAIETADVALMGQDLRH 691
Query: 627 LPKAIQIARKTQRIVWENIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIAVFNAMR 686
LP+A+ AR++++I+ +N+ +L + + L +FG + V +I + N +R
Sbjct: 692 LPQALDHARRSRQIMVQNVGLSLSIITVLMPLALFGILGLAAVVLVHEFTEVIVIANGVR 751
Query: 687 VLR 689
R
Sbjct: 752 AGR 754
>gb|AAG10086.1|AF296446_2 (AF296446) CopA [Streptococcus mutans]
Length = 742
Score = 330 bits (837), Expect = 3e-89
Identities = 230/736 (31%), Positives = 383/736 (51%), Gaps = 61/736 (8%)
Query: 8 LEGLDCASCAYEIEEALRK-EGFKFAVVNFATKEAIIEGDIEKAKEV-IKKVEPDVEVVE 65
++G+ CASCA +E A++K +G + AVVN T++ I+ D K E + K
Sbjct: 8 IDGMTCASCAINVENAVKKLDGIESAVVNLTTEKMTIDYDAAKVSEADVTKAVAGAGYGA 67
Query: 66 EVHIHDHAHGEFEKRTIYFIGISLVLFTIGILMRYYYAIDNTLVFGLFLASYLISGWKVL 125
+V+ A + ++ GI L I + I + GL L ++L L
Sbjct: 68 KVYDPTTAESQKDREEHKLAGIKKRLLWTSIFTIPLFYIAMGSMVGLPLPNFLAPSSAPL 127
Query: 126 KSAIVNSL--------NGNVFDENF------------LIAVATIGAFLIKEYP------- 158
A+V L + + +D F L+++AT AFL Y
Sbjct: 128 TYAMVLLLLTIPVIVLSWSFYDNGFRSLFKGHPNMDSLVSLATTAAFLYSLYGTYHVYLG 187
Query: 159 ----------EGVAVMLFYV-IGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKV 207
E VAV+L + +G++ + ++ ++ +IK L+ L A+ A L+RDG +KV
Sbjct: 188 HTHHAHHLYYESVAVILTLITLGKYFETLSKGRTSDAIKKLMHLSAKEATLIRDGEEIKV 247
Query: 208 KPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLT 267
E++++ D I+VKPGEK+PVDG ++ G S++D S LTGES+P + +G IN
Sbjct: 248 PIEQVQIRDQILVKPGEKIPVDGRVLSGHSAIDESMLTGESIPIEKMADSPVYAGSINGQ 307
Query: 268 GLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPP 327
G L + +E+ +S+I++LVENA KA K + + + P ++ IA L
Sbjct: 308 GSLTFEAEKVGNETLLSQIIKLVENAQQTKAPIAKIADKVSAVFVPVIITIAILTGLFWY 367
Query: 328 LVFKESFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDA 387
V + FT + ++ +LVI+CPCAL L+ P G GRAA+ GIL K + L+
Sbjct: 368 FVMGQDFTFSMTISVAVLVIACPCALGLATPTAIMVGTGRAAENGILYKRGDVLELAHQI 427
Query: 388 SIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKE-I 446
+ + FDKTGT+T+G K + + ++++ A EA S HP+++AI + KE
Sbjct: 428 NTIVFDKTGTITQG--KPEVVHQFSYHDRTDLVQVTAALEALSEHPLSQAIVDYAKKEGT 485
Query: 447 NEAEITEYEEIAGHGVRARIDSVEVMVGNDKLLHRSNI--EHDTCKVKGTIAH------V 498
+ + ++ + G G++ + ++VGN+KL+ ++NI E K A V
Sbjct: 486 HLLAVDDFTSLTGLGLKGCVADETLLVGNEKLMRQANISLEQAQADFKAATAQGQTPIFV 545
Query: 499 VIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYA 558
DGQ G I I+D++K D+ VK L+ +GV +V M+TGD+ + A+ IAK++G+ +
Sbjct: 546 ASDGQLLGLITIADKVKNDSAATVKALQNMGV-EVAMLTGDNEETAQAIAKEVGITFVIS 604
Query: 559 ELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVV 618
++ ++K + I L+ E K+ VGDGINDAP LA AD+G++MG+ G+D A+E+AD+V
Sbjct: 605 QVFSQEKTQAILDLQAE--GKKVAMVGDGINDAPALATADIGISMGS-GTDIAMESADIV 661
Query: 619 IMDDKPSKLPKAIQIARKT-----QRIVWENIIFALGVKLAFIGLGIFGKATMWEAVFAD 673
+M + KA++I+R T + + W I L V +A L +FG + + + A
Sbjct: 662 LMKPAMLDIIKALKISRVTIINIKENLFWAFIYNVLSVPIAMGVLYLFG-GPLLDPMIAG 720
Query: 674 VGVALIAVFNAMRVLR 689
+ ++ +V + LR
Sbjct: 721 LAMSFSSVSVVLNALR 736
>pir||T03515 probable cadmium-transporting ATPase (EC 3.6.1.-) - Rhodobacter
capsulatus >gi|3128316|gb|AAC16168.1| (AF010496)
probable cadmium-transporting ATPase [Rhodobacter
capsulatus]
Length = 630
Score = 328 bits (833), Expect = 1e-88
Identities = 203/588 (34%), Positives = 322/588 (54%), Gaps = 21/588 (3%)
Query: 114 LASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEYPEGVAVMLFYVIGEFL 173
L+ +L G A+ + D + L+ VA + A + EG ++ + + L
Sbjct: 42 LSVFLTGGVPAAYRAVGALIEERQLDIDLLMVVAALAAAAVGAALEGAVLLTLFSLSTTL 101
Query: 174 QDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVII 233
+ A+ ++RR+I+AL+ L+ + A + G V+V E L GD++I++PG +VPVDGVI+
Sbjct: 102 EHRAMGRARRAIEALMELRPDRALKRQGGDTVEVAVETLVPGDVVILRPGARVPVDGVIV 161
Query: 234 EGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENA 293
G ++D S +TGES+P G ++ +NL G+L++ V REL ESTV+R++ LV A
Sbjct: 162 AGEGAIDESTITGESVPVHKAPGAQVFEATVNLHGVLEIEVRRELGESTVARMIALVTEA 221
Query: 294 SARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKESFTSWVYRALVILVISCPCAL 353
A ++ +E+F F YT AV+ +A + A + + +Y+A +LV + PCA+
Sbjct: 222 QAARSPSERFSAWFGQRYTVAVL-LAAVSAFAAFWAIGHGWNAALYKAATLLVAASPCAI 280
Query: 354 VLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNG 413
V+S+P + AA+ G+L KG L+ L AFDKTGTLT G ++ I
Sbjct: 281 VISVPAAILSALSVAARGGVLFKGGAALETLAKVETFAFDKTGTLTTGKQEIVDIHCEG- 339
Query: 414 FTEEEILRFAALA--EAHSNHPIAKAIRE-AYGKEINEAEITEYEEIAGHGVRARIDSVE 470
+E L A LA EA S HPIA AIR+ + I + E + G G+ A D
Sbjct: 340 ---DEALFLARLAGIEAQSEHPIATAIRQHVAARGIVPLPVREARAVPGEGMVAVDDEGV 396
Query: 471 VMVGNDKLLHRSNIE-HDTCKVKGTIAH----VVIDGQYA---GYIVISDEIKEDAHLAV 522
+ GN +L R +T + + + +V+ G+ A G + D ++ +
Sbjct: 397 IWAGNARLAQRMGARAAETLALPAVLENAPRTLVLLGRGAKILGGVTCEDRPRDSTPAGL 456
Query: 523 KELKRLGVRKVVMVTGDSRDVAEEIAKQLGL--DGFYAELLPEDKVKIIEKLEKEKGNGK 580
L+ GV ++ M+TGD R VAE I +LG+ D +A+L PEDKVKI+ L G+
Sbjct: 457 AALRAGGVGQIAMLTGDRRAVAERIGAELGIGADEIHADLRPEDKVKIVADL---TARGR 513
Query: 581 LVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRI 640
+ FVGDG+NDA LARADVG+AMG GS+ A++ ADV ++ D S+L +A ++A +T RI
Sbjct: 514 VAFVGDGVNDAAALARADVGIAMGVAGSEVALQAADVALLADDISRLSEAHRLAGRTARI 573
Query: 641 VWENIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIAVFNAMRVL 688
+ +N++FA+G + G+F + + AV G ++ V N +R+L
Sbjct: 574 IRQNLVFAMGAMAVLVLSGLFFELPLPVAVIGHEGGTVLVVLNGLRLL 621
>sp|P32113|COPA_ENTHR COPPER/POTASSIUM-TRANSPORTING ATPASE A >gi|538893|pir||A45995
copper-transporting ATPase (EC 3.6.1.-) copA -
Enterococcus hirae >gi|290642|gb|AAA61835.1| (L13292)
ATPase [Enterococcus hirae]
Length = 727
Score = 324 bits (821), Expect = 2e-87
Identities = 219/702 (31%), Positives = 375/702 (53%), Gaps = 69/702 (9%)
Query: 8 LEGLDCASCAYEIEEALRKE-GFKFAVVNFATKEAIIEGDIEKAKEVIKKVEPDVEVVEE 66
+ G+ CA+C+ IE+ L ++ G A VN AT++A ++ + +IK VE +
Sbjct: 12 ITGMTCANCSARIEKELNEQPGVMSATVNLATEKASVKYTDTTTERLIKSVE---NIGYG 68
Query: 67 VHIHDHAHGEF---EKRT------------------IYFIGISLVLFTIGILMRYYYAID 105
++D AH + EK+T + I+++L + G ++ +++
Sbjct: 69 AILYDEAHKQKIAEEKQTYLRKMKFDLIFSAILTLPLMLAMIAMMLGSHGPIVSFFHLSL 128
Query: 106 NTLVFGLFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEY-------- 157
L+F L + Y+ GW+ K A ++L + + L+A+ T AF + Y
Sbjct: 129 VQLLFALPVQFYV--GWRFYKGAY-HALKTKAPNMDVLVAIGTSAAFALSIYNGFFPSHS 185
Query: 158 -----PEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEEL 212
++ ++G++L+ A K+ +IK +++L+ + A ++RDG + +E+
Sbjct: 186 HDLYFESSSMIITLILLGKYLEHTAKSKTGDAIKQMMSLQTKTAQVLRDGKEETIAIDEV 245
Query: 213 KVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKV 272
+ DI++++PGE+VP DG II GTS++D S LTGES+P KE D + G IN GL+++
Sbjct: 246 MIDDILVIRPGEQVPTDGRIIAGTSALDESMLTGESVPVEKKEKDMVFGGTINTNGLIQI 305
Query: 273 RVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKE 332
+V++ ++ +++I+++VE+A KA ++ + + + P V+ +A + V + K+
Sbjct: 306 QVSQIGKDTVLAQIIQMVEDAQGSKAPIQQIADKISGIFVPIVLFLALVTLLVTGWLTKD 365
Query: 333 SFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAF 392
+ ++ ++ +LVI+CPCAL L+ P G G A GILIKG L+ + +
Sbjct: 366 WQLALLH-SVSVLVIACPCALGLATPTAIMVGTGVGAHNGILIKGGEALEGAAHLNSIIL 424
Query: 393 DKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKEINEAE-- 450
DKTGT+T+G +VT + +EI+ E S HP+ KAI AYG ++
Sbjct: 425 DKTGTITQGRPEVTDV-----IGPKEIISLFYSLEHASEHPLGKAI-VAYGAKVGAKTQP 478
Query: 451 ITEYEEIAGHGVRARIDSVEVMVGNDKLLHRSNIEHDTCKVKG--------TIAHVVIDG 502
IT++ G G+ I+ V G K L N+ D + + T+ + +
Sbjct: 479 ITDFVAHPGAGISGTINGVHYFAGTRKRLAEMNLSFDEFQEQALELEQAGKTVMFLANEE 538
Query: 503 QYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDG--FYAEL 560
Q G I ++D+IKEDA A+++L++ GV V MVTGD++ A+ I KQ+G+D +AE+
Sbjct: 539 QVLGMIAVADQIKEDAKQAIEQLQQKGV-DVFMVTGDNQRAAQAIGKQVGIDSDHIFAEV 597
Query: 561 LPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIM 620
LPE+K +EKL+K K+ VGDGINDAP L ADVG+AMG+ G+D A+ETADV +M
Sbjct: 598 LPEEKANYVEKLQK--AGKKVGMVGDGINDAPALRLADVGIAMGS-GTDIAMETADVTLM 654
Query: 621 DDKPSKLPKAIQIARKT-----QRIVWENIIFALGVKLAFIG 657
+ + + + I ++ T Q + W I +G+ A G
Sbjct: 655 NSHLTSINQMISLSAATLKKIKQNLFWAFIYNTIGIPFAAFG 696
>pir||T35947 probable cation-transporting ATPase - Streptomyces coelicolor
>gi|4158206|emb|CAA22769.1| (AL035206) putative
cation-transporting ATPase [Streptomyces coelicolor
A3(2)]
Length = 638
Score = 322 bits (817), Expect = 7e-87
Identities = 197/584 (33%), Positives = 315/584 (53%), Gaps = 17/584 (2%)
Query: 112 LFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEYPEGVAVMLFYVIGE 171
L+ +Y GW+ + +L D + L+ VA +GA I + +G +++ +
Sbjct: 59 LYAVAYASGGWEPALEGL-RALREKTLDVDLLMIVAALGAAAIGQVLDGGLLIVIFATSG 117
Query: 172 FLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGV 231
L+ +A ++ S++ LL L A +R+G V +L VGD+++V+PGE++ DG
Sbjct: 118 ALEALATARTADSVRGLLDLAPTTATRLREGGEETVPTADLAVGDLVLVRPGERIGADGT 177
Query: 232 IIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVE 291
++EG VD + +TGES+P + GD++ +G +N TG L+VRV R+ ++S ++RI+ LVE
Sbjct: 178 VVEGAGEVDQATITGESLPVLKRPGDDVFAGTLNGTGALRVRVGRDPADSVIARIVTLVE 237
Query: 292 NASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKESFTSWVYRALVILVISCPC 351
AS KA T+ FI + Y+ VV +ATL PL F T + RA+ ++++ PC
Sbjct: 238 EASRTKAPTQLFIEKIEQRYSVGVV-VATLAVFGIPLAFGAGLTDALLRAMTFMIVASPC 296
Query: 352 ALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKI--E 409
A+VL+ I A + G+L+K + ++ L + A DKTGTLT+G +VT +
Sbjct: 297 AVVLATMPPLLSAIANAGRHGVLVKSAVAMERLGEIDTAALDKTGTLTEGTPEVTAVTPA 356
Query: 410 TRNGFTEEEILRFAALAEAHSNHPIAKAI-REAYGKEINEAEITEYEEIAGHGVRARIDS 468
G E+ +L AA AE S HP+A+AI A + ++ A ++ G GV A ID
Sbjct: 357 AGAGVDEDALLALAAAAEHPSEHPLARAIVAAARARGLHIAPADDFTAAPGRGVTAVIDG 416
Query: 469 VEVMVGNDKLLHRSNIEHDTCKVKG--TIAHVVIDGQYAGYIVISDEIKEDAHLAVKELK 526
V VG R++ G T V DG + G + ++D +++DA A L
Sbjct: 417 RTVHVG------RADPTEGAAGAAGAETTVRVTRDGTHLGTLALTDRLRDDAARATTRLT 470
Query: 527 RLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGD 586
L ++TGD A +A G+ A LLPEDKV + E+E+ K++FVGD
Sbjct: 471 ALTGTAPTLLTGDHAAAAARVADATGITDVRAGLLPEDKVGAVR--ERERAGHKVLFVGD 528
Query: 587 GINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENII 646
G+NDAP LA A GVAMG GSD A+ETAD V++ D+ + +P + ++R+ +R+V +N+
Sbjct: 529 GVNDAPALAAAHAGVAMGRAGSDLALETADAVVVRDELTAVPAVVDLSRRARRLVVQNLA 588
Query: 647 FALGVKLAFIGL-GIFGKATMWEAVFADVGVALIAVFNAMRVLR 689
A GV + + L + G + V G ++ N +R+LR
Sbjct: 589 VA-GVFITVLVLWDLIGHLPLPLGVAGHEGSTVLVGLNGLRLLR 631
>emb|CAB81005.1| (AL161576) cadmium-transporting ATPase-like protein [Arabidopsis
thaliana]
Length = 711
Score = 321 bits (814), Expect = 2e-86
Identities = 189/613 (30%), Positives = 325/613 (52%), Gaps = 62/613 (10%)
Query: 84 FIGISLVLFTIGILMRYYYAIDNTLVFGLFLASYLISGWKVLKSAIVNSLNGNVFDENFL 143
F +S VL + +Y ++ L + + + + +L A+ S+ D N L
Sbjct: 96 FAIVSGVLLVLSFFKYFYSPLE-----WLAIVAVVAGVFPILAKAVA-SVTRFRLDINAL 149
Query: 144 IAVATIGAFLIKEYPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGT 203
+A I ++++ E ++ + + ++L+ A K+ + +L++L A + G
Sbjct: 150 TLIAVIATLCMQDFTEAATIVFLFSVADWLESSAAHKASIVMSSLMSLAPRKAVIADTGL 209
Query: 204 VVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGM 263
V V +E+ + ++ VK GE +P+DGV+++G+ VD LTGES P + + +++
Sbjct: 210 EVDV--DEVGINTVVSVKAGESIPIDGVVVDGSCDVDEKTLTGESFPVSKQRESTVMAAT 267
Query: 264 INLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIA 323
INL G +KV+ T + V+++ +LVE A + KT++FI + + YYTPAVV A A
Sbjct: 268 INLNGYIKVKTTALARDCVVAKMTKLVEEAQKSQTKTQRFIDKCSRYYTPAVVVSAACFA 327
Query: 324 TVPPLVFKESFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDA 383
+P L+ + + W + ALV+LV CPC L+LS P+ F + +AA G LIK + L+
Sbjct: 328 VIPVLLKVQDLSHWFHLALVVLVSGCPCGLILSTPVATFCALTKAATSGFLIKTGDCLET 387
Query: 384 LKDASIVAFDKTGTLTKGVFKVTKIETRN-GFTEEEILRFAALAEAHSNHPIAKAIREAY 442
L IVAFDKTGT+TK F V+ + + ++L + + E S+HP+A A+ + Y
Sbjct: 388 LAKIKIVAFDKTGTITKAEFMVSDFRSLSPSINLHKLLYWVSSIECKSSHPMAAALID-Y 446
Query: 443 GKEIN---EAEITE-YEEIAGHGVRARIDSVEVMVGNDKLLHRSNIEHDTCKVKGTIAHV 498
+ ++ + +I E ++ G GV RID ++ +GN ++ R+ G + +
Sbjct: 447 ARSVSVEPKPDIVENFQNFPGEGVYGRIDGQDIYIGNKRIAQRA----------GCLTGI 496
Query: 499 VIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQL--GLDGF 556
+ M+TGD++D A +QL LD
Sbjct: 497 ---------------------------------QTAMLTGDNQDAAMSTQEQLENALDIV 523
Query: 557 YAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETAD 616
++ELLP+DK +II+ K G + VGDG+NDAP LA+AD+G++MG GS A ET D
Sbjct: 524 HSELLPQDKARIIDDF---KIQGPTMMVGDGLNDAPALAKADIGISMGISGSALATETGD 580
Query: 617 VVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGLGIFGKATMWEAVFADVGV 676
+++M + K+PK +++A+++ + V EN++ ++ +K A + LG G +W AV AD G
Sbjct: 581 IILMSNDIRKIPKGMRLAKRSHKKVIENVVLSVSIKGAIMVLGFVGYPLVWAAVLADAGT 640
Query: 677 ALIAVFNAMRVLR 689
L+ + N+M +LR
Sbjct: 641 CLLVILNSMMLLR 653
>sp|O53160|CTPD_MYCTU PROBABLE CATION-TRANSPORTING P-TYPE ATPASE D
>gi|7436389|pir||H70872 probable ctpD protein -
Mycobacterium tuberculosis (strain H37RV)
>gi|2791403|emb|CAA15997.1| (AL021184) ctpD
[Mycobacterium tuberculosis]
Length = 657
Score = 321 bits (814), Expect = 2e-86
Identities = 199/608 (32%), Positives = 331/608 (53%), Gaps = 12/608 (1%)
Query: 87 ISLVLFTIGILMRYYYAIDNTLVFGLFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAV 146
++L+LF G++ + A + + + L+LA YL GW + +L D + L+
Sbjct: 43 VALLLFLAGLVAQLNGAPE-AMWWTLYLACYLAGGWGSAWAG-AQALRNKALDVDLLMIA 100
Query: 147 ATIGAFLIKEYPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVR-DGTVV 205
A +GA I + +G +++ + L D+A + S+K LL L + A +V+ DG+
Sbjct: 101 AAVGAVAIGQIFDGALLIVIFATSGALDDIATRHTAESVKGLLDLAPDQAVVVQGDGSER 160
Query: 206 KVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMIN 265
V EL VGD ++V+PG+++P DG ++ G S VD ++TGESMP GDE+ +G +N
Sbjct: 161 VVAASELVVGDRVVVRPGDRIPADGAVLSGASDVDQRSITGESMPVAKARGDEVFAGTVN 220
Query: 266 LTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATV 325
+G+L + VTR+ S++ V+RI+ELV +ASA KAKT+ FI + Y+ +V ATL V
Sbjct: 221 GSGVLHLVVTRDPSQTVVARIVELVADASATKAKTQLFIEKIEQRYSLGMVA-ATLALIV 279
Query: 326 PPLVFKESFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALK 385
PL+F + RA+ ++++ PCA+VL+ I A + G+L+K + ++ L
Sbjct: 280 IPLMFGADLRPVLLRAMTFMIVASPCAVVLATMPPLLSAIANAGRHGVLVKSAVVVERLA 339
Query: 386 DASIVAFDKTGTLTKGVFKVTKIE--TRNGFTEEEILRFAALAEAHSNHPIAKAI-REAY 442
D SIVA DKTGTLT+G+ ++ + N +L+ AA AE S HP+ +AI EA
Sbjct: 340 DTSIVALDKTGTLTRGIPRLASVAPLDPNVVDARRLLQLAAAAEQSSEHPLGRAIVAEAR 399
Query: 443 GKEINEAEITEYEEIAGHGVRARIDSVEVMVGNDKLLHRSNIEH--DTCKVKGTIAHVVI 500
+ I ++ + G GV A + + V + + + + + T A V++
Sbjct: 400 RRGIAIPPAKDFRAVPGCGVHALVGNDFVEIASPQSYRGAPLAELAPLLSAGATAAIVLL 459
Query: 501 DGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAEL 560
DG G + ++D+++ DA +V + L V++TGD+ A +A+ G+ A L
Sbjct: 460 DGVAIGVLGLTDQLRPDAVESVAAMAALTAAPPVLLTGDNGRAAWRVARNAGITDVRAAL 519
Query: 561 LPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIM 620
LPE KV+++ L + G +++ VGDG+NDAP +A A VAMGA G+D ++TAD V +
Sbjct: 520 LPEQKVEVVRNL--QAGGHQVLLVGDGVNDAPAMAAARAAVAMGA-GADLTLQTADGVTI 576
Query: 621 DDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIA 680
D+ +P I +AR+ +R+V N+ A + +FG+ + V G ++
Sbjct: 577 RDELHTIPTIIGLARQARRVVTVNLAIAATFIAVLVLWDLFGQLPLPLGVVGHEGSTVLV 636
Query: 681 VFNAMRVL 688
N MR+L
Sbjct: 637 ALNGMRLL 644
>gi|11497769 copper-transporting ATPase, P-type (copB) [Archaeoglobus fulgidus]
>gi|7436384|pir||H69268 copper-transporting ATPase,
P-type (copB) homolog - Archaeoglobus fulgidus
>gi|2650494|gb|AAB91079.1| (AE001096)
copper-transporting ATPase, P-type (copB) [Archaeoglobus
fulgidus]
Length = 690
Score = 318 bits (807), Expect = 1e-85
Identities = 200/563 (35%), Positives = 321/563 (56%), Gaps = 31/563 (5%)
Query: 108 LVFGLFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATI--------------GAFL 153
++F L A Y G+ LK I + L LIAVA G F
Sbjct: 95 ILFLLSSAVYFYGGYPFLKG-IFDELRRRQPGMMTLIAVAISVAYFYSSAVVFGLKGKFF 153
Query: 154 IKEYPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELK 213
E + +ML +G +++ +V + R+++ L+ + A+L++DG +V+VK E LK
Sbjct: 154 FWELATLIDIML---LGHYIEMRSVLGASRALEELVKIMPSEAHLLKDGEIVEVKVENLK 210
Query: 214 VGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVR 273
GD ++VKPGEK+PVDG+++EG S V+ + LTGES P K GD ++ G IN G L V
Sbjct: 211 PGDKVLVKPGEKIPVDGIVVEGESFVNEAMLTGESKPVAKKPGDTVIGGAINGEGSLVVE 270
Query: 274 VTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKES 333
V + ++ +++++ELV A K++T+ R A T + + ++ + L +
Sbjct: 271 VEKTGKDTYLNQVIELVRQAQESKSRTQDLANRAALLLTVIALTVGSVTLAI-WLAYIAD 329
Query: 334 FTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFD 393
F + RA+ ++VI+CP AL L+IPL AAK G+LI+ + KD V FD
Sbjct: 330 FAFAIERAVTVMVITCPHALGLAIPLVVAVSTSLAAKSGLLIRDRQAFERAKDLQAVIFD 389
Query: 394 KTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAI-REAYGKEINEAEIT 452
KTGTLT+G F VT I N +E+E+L+ AA EA S HPIA AI EA + E+
Sbjct: 390 KTGTLTEGRFGVTDIVGFN-HSEDELLQIAASLEARSEHPIAAAIVEEAEKRGFGLTEVE 448
Query: 453 EYEEIAGHGVRARIDSVEVMVGNDKLLHRSNIEHDTCKVK-----GTIAHVVIDGQYAGY 507
E+ I G GV ++ MV + + I+ D K T+ ++ +G+ +G
Sbjct: 449 EFRAIPGKGVEGIVNGRRYMVVSPGYIRELGIKTDESVEKLKQQGKTVVFILKNGEVSGV 508
Query: 508 IVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVK 567
I ++D I+ ++ A+ +LK +G+ K +M+TGD+R VA+ +A++LGLD ++AE+LP +K
Sbjct: 509 IALADRIRPESREAISKLKAIGI-KCMMLTGDNRFVAKWVAEELGLDDYFAEVLPHEKA- 566
Query: 568 IIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKL 627
EK+++ + VGDG+NDAP LA+ADVG+A+GA G+D A+ETAD+V++ + P +
Sbjct: 567 --EKVKEVQQKYVTAMVGDGVNDAPALAQADVGIAIGA-GTDVAVETADIVLVRNDPRDV 623
Query: 628 PKAIQIARKTQRIVWENIIFALG 650
++++RKT + +N+++A G
Sbjct: 624 AAIVELSRKTYSKMKQNLLWATG 646
>pir||H70798 probable cation-transporting ATPase - Mycobacterium tuberculosis
(strain H37RV) >gi|2960167|emb|CAA18065.1| (AL022121)
hypothetical protein Rv3743c [Mycobacterium
tuberculosis]
Length = 660
Score = 317 bits (803), Expect = 3e-85
Identities = 202/617 (32%), Positives = 330/617 (52%), Gaps = 19/617 (3%)
Query: 87 ISLVLFTIGILMRYYYAIDNTLVFGLFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAV 146
++L LF+ G+L + A + + LFLA Y GW+ + + +L D + L+ V
Sbjct: 36 LALGLFSAGLLTQLCGA-PQWVRWALFLACYATGGWEPGLAGL-QALQRRTLDVDLLMVV 93
Query: 147 ATIGAFLIKEYPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLV-RDGTVV 205
A IGA I + EG +++ + L+ + ++ S++ L+ L A V G
Sbjct: 94 AAIGAAAIGQIAEGALLIVIFATSGALEALVTARTADSVRGLMGLAPGTATRVGAGGGEE 153
Query: 206 KVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMIN 265
V +L++GDI++V+PGE++ D ++ G S VD + +TGE +P GD++ +G +N
Sbjct: 154 TVNAADLRIGDIVLVRPGERISADATVLAGGSEVDQATVTGEPLPVDKSIGDQVFAGTVN 213
Query: 266 LTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATV 325
TG L++RV R +S V+RI LVE AS KA+T+ FI + Y+ +V + + V
Sbjct: 214 GTGALRIRVDRLARDSVVARIATLVEQASQTKARTQLFIEKVEQRYSIGMVAVTLAVFAV 273
Query: 326 PPLVFKESFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALK 385
PPL + E+ + RA+ ++++ PCA+VL+ I A + G+L K + ++ L
Sbjct: 274 PPL-WGETLQRALLRAMTFMIVASPCAVVLATMPPLLAAIANAGRHGVLAKSAIVMEQLG 332
Query: 386 DASIVAFDKTGTLTKGVFKVTKIET-RNGFTEEEILRFAALAEAHSNHPIAKAI-REAYG 443
+ +AFDKTGTLT+G ++ I FT++E+LR AA AE S HP+ AI + A
Sbjct: 333 TTTRIAFDKTGTLTRGTPELAGIWVYERRFTDDELLRLAAAAEYPSEHPLGAAIVKAAQS 392
Query: 444 KEINEAEITEYEEIAGHGVRARIDSVEVMVGN---------DKLLHRSNIEH-DTCKVKG 493
+ I + E+ G V AR+D + VG+ L S I D + +G
Sbjct: 393 RRIRLPTVGEFTAHPGCRVTARVDGHVIAVGSATALLGTAGAAALEASMITAVDFLQGEG 452
Query: 494 -TIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLG 552
T+ VV D G + I+D+++ +A A+ +L K V++TGD+R A+ + Q+G
Sbjct: 453 YTVVVVVCDSHPVGLLAITDQLRPEAAAAISAATKLTGAKPVLLTGDNRATADRLGVQVG 512
Query: 553 LDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAI 612
+D A LLP+DKV + +L + G +L VGDGINDAP LA A VG+AMG+ S+ +
Sbjct: 513 IDDVRAGLLPDDKVAAVRQL--QAGGARLTVVGDGINDAPALAAAHVGIAMGSARSELTL 570
Query: 613 ETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGLGIFGKATMWEAVFA 672
+TAD V++ D + +P I ++R+ +RIV N+I A+ + + + V
Sbjct: 571 QTADAVVVRDDLTTIPTVIAMSRRARRIVVANLIVAVTFIAGLVVWDLAFTLPLPLGVAR 630
Query: 673 DVGVALIAVFNAMRVLR 689
G +I N +R+LR
Sbjct: 631 HEGSTIIVGLNGLRLLR 647
>gb|AAB06719.1| (U15554) P-type adenosine triphosphatase [Listeria monocytogenes]
Length = 653
Score = 316 bits (802), Expect = 4e-85
Identities = 205/579 (35%), Positives = 323/579 (55%), Gaps = 35/579 (6%)
Query: 108 LVFGLFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEYP--------- 158
++F Y SG L++A+ + N + + + L+ + T A++ Y
Sbjct: 39 ILFAFGSLVYWFSGLPFLRTAVASFKNHHA-NMDTLVGLGTTIAYVYSLYAMFARPNETY 97
Query: 159 -EGVAVMLFYVI-GEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGD 216
E VAV++ ++ G + ++ + ++ L+ L+A+ A ++RDG +K+ EE+ VGD
Sbjct: 98 FEAVAVVITLILLGSYFEERMKASASSAVDKLMGLQAKDAEVLRDGEFIKLPIEEIIVGD 157
Query: 217 IIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTR 276
+I VKPGEKV VDG I+EGTS++D S +TGESMP GD ++ +N TG VT+
Sbjct: 158 LIRVKPGEKVAVDGQIVEGTSTLDESMVTGESMPVEKGPGDNVIGATLNNTGSFTFEVTK 217
Query: 277 ELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKESFTS 336
+++ +S I E+V +A +A +K + R ++ + P V+ I+ L V + + +
Sbjct: 218 VGADTMLSNIAEMVRHAQNSRAPIQKTVDRISNIFVPIVLMISILTFIVWYVFLGSTLVT 277
Query: 337 WVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTG 396
+ ++ +++I+CPCAL ++ P G GR+AK GILIK + L+A D V DKTG
Sbjct: 278 AMIFSVSVMIIACPCALGIATPTALMVGTGRSAKLGILIKNAEVLEATHDIKTVVMDKTG 337
Query: 397 TLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKA-IREAYGKEINEAEITEYE 455
T+T G +VT I + +E EILR AA E S HP+A A I EA K+I A +
Sbjct: 338 TITVGKPQVTDIISIGRISENEILRIAAGLEDSSEHPLALAVINEAKDKKITPAVAKNFT 397
Query: 456 EIAGHGVRARIDSVEVMVGNDKLLHRSNIEHDTCKVK--------GTIAHVVIDGQYAGY 507
I+G GV+A ID + +GND+L N+ D KVK T+ V DGQ
Sbjct: 398 AISGKGVQALIDGKQAFIGNDRLSDDFNMT-DDLKVKMTSLQAQAKTVVLVGYDGQIIAL 456
Query: 508 IVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVK 567
I I D K + A++ +++ G VM+TGD+R VA+ IA +G+D A+++P DK +
Sbjct: 457 IGIQDAPKSSSKAAIRAMQKSGFH-TVMLTGDNRLVAQAIADDIGIDEVIADVMPGDKAQ 515
Query: 568 IIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKL 627
I KL+++ G + FVGDGINDAP L+ A VG+AMG+ GSD AIE+ +V++ + +
Sbjct: 516 HIRKLQEK---GAVAFVGDGINDAPALSTATVGIAMGS-GSDIAIESGGIVLVKNDLMDV 571
Query: 628 PKAIQIARKTQ-----RIVWENIIFALGVKLAFIGLGIF 661
++ +ARKT + W I +G+ +A GIF
Sbjct: 572 VTSLVLARKTYSRILINLFWAFIYNVIGIPVA---AGIF 607
>pir||H70396 cation transporting ATPase (E1-E2 family) - Aquifex aeolicus
>gi|2983590|gb|AAC07161.1| (AE000724) cation
transporting ATPase (E1-E2 family) [Aquifex aeolicus]
Length = 664
Score = 316 bits (801), Expect = 5e-85
Identities = 211/620 (34%), Positives = 344/620 (55%), Gaps = 45/620 (7%)
Query: 70 HDHAH-GEFEKRTIYFIGISLVLFT---------IGILMRYYYAIDNTLVFGLFLASYLI 119
H+HAH E KR I V IGI + + Y+ N ++ L A ++
Sbjct: 19 HEHAHHAEIIKRKALITTILTVPVVVLSPSIQELIGIKVSFPYS--NWVILLLSTAVFIY 76
Query: 120 SGWKVLKSAI---------VNSLNGNVFDENFLIAVATI---GAFLIKEYPEGVAVMLFY 167
G LK + + +L G ++ +V T G E + VML+
Sbjct: 77 GGTFFLKGMLEELKKKNPGMMTLVGLAISVAYIYSVYTFFFGGKEFFWELTTLIVVMLW- 135
Query: 168 VIGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIVKPGEKVP 227
G +++ +V + R+++ L+ L A+LV ++ V E+LK GD+++V+PGEK+P
Sbjct: 136 --GHYVEMKSVLGAGRALEELVKLIPSKAHLVTQKGLIDVPVEKLKKGDLVLVRPGEKIP 193
Query: 228 VDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRIL 287
DG ++EG + VD S LTGES P K GD+++ G +NL G +KVRV + E+ + +++
Sbjct: 194 TDGTVVEGNTHVDESMLTGESRPVPKKPGDKVIGGSVNLEGSIKVRVEKTGEETYLKQVI 253
Query: 288 ELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKESFTSWVYRALVILVI 347
+LV+ A K K + R A Y T V + + I+ + + V RA+ ++V
Sbjct: 254 KLVKEAQESKTKLQSLADRAAFYLTVIAVSLGS-ISLLFWWYYLGDLNFAVERAVTVMVT 312
Query: 348 SCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTK 407
+CP AL L+IPL +A+ GIL++ L+ KD +V FDKTGTLT+G VT+
Sbjct: 313 ACPHALGLAIPLVVSISTSYSARNGILVRNRLALEKAKDIDVVVFDKTGTLTEGKLGVTE 372
Query: 408 IETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKEINEAEITEYEEIAGHGVRARID 467
+ T++ E E L+F A E HS H IA+AI +Y KE + E+ ++ G GV +
Sbjct: 373 VITKD-IEEGEFLKFVASVENHSEHVIARAI-VSYAKE--KEEVKNFKAFPGKGVCGEVS 428
Query: 468 SVEVMVGNDKLLHRSNIEHDTCKVK---------GTIAHVVIDGQYAGYIVISDEIKEDA 518
V VG + L N++ D V+ T+ +DG+ AG I ++D IKE++
Sbjct: 429 GRNVCVGTLEFLKEINVKLDEELVERARSLQSEGKTVVFASMDGKLAGIIALADRIKEES 488
Query: 519 HLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGN 578
+ AV+ LK LG +KVVM+TGDS +VA+ +AK+L +D ++A +LP +K + I++L+ ++G
Sbjct: 489 YEAVRSLKELG-KKVVMITGDSEEVAKYVAKELEMDEYFARVLPHEKAQKIKELQ-DRGY 546
Query: 579 GKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQ 638
+ VGDG+NDAP L +ADVG+A+G+ G+D AIE+ADV+++ P + K I++++ T
Sbjct: 547 -SVAMVGDGVNDAPALIQADVGIAIGS-GTDIAIESADVILVKSDPRDVVKVIKLSQVTV 604
Query: 639 RIVWENIIFALGVKLAFIGL 658
+ +N+ +A+G + + L
Sbjct: 605 SKMLQNLFWAVGYNVITLPL 624
>pir||F72624 probable cation-transporting ATPase APE1454 - Aeropyrum pernix
(strain K1) >gi|5105138|dbj|BAA80452.1| (AP000061) 835aa
long hypothetical cation-transporting ATPase [Aeropyrum
pernix]
Length = 835
Score = 315 bits (798), Expect = 1e-84
Identities = 216/673 (32%), Positives = 364/673 (53%), Gaps = 59/673 (8%)
Query: 19 EIEEALRKEGFKFAVVNFATKEAIIEGDIEKAKEVIKKVEPDVEVVEEVHIHDHAHGEFE 78
E+ EALRK G+K A ++++E + E+ + ++ ++ + + +
Sbjct: 125 EVLEALRKAGYK---AEMAEGKSLVEAEAEEERRLL--LDGLISITASI----------- 168
Query: 79 KRTIYFIGISLVLFT----IGILMRYYYAIDNTLVFGLFLAS----YLISGWKVLKS--- 127
+Y+I ++L G ++ YY A+ VF + L +L+ ++ LK+
Sbjct: 169 ---VYYILLALERLAGVEAAGAVLPYYGAV----VFAIVLLGPGRRFLVGAYRSLKNGTP 221
Query: 128 ---AIVNSLNGNVFDENFLIAVATIGAFLIKEYPEGVAVML-FYVIGEFLQDMAVDKSRR 183
A+V+ +++ F AT+ + Y EG+ +++ F +IG +++ + +
Sbjct: 222 GMDALVSLGTLSIY---FYSLAATLNIIRGELYYEGIGLIIGFVLIGRYIESKVKKGTGK 278
Query: 184 SIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSA 243
+++ L LK + A ++R V+V E+K GD+++V+ GE++PVDG +++G + VD S
Sbjct: 279 AVENLAKLKPQKARVLRGRREVEVDVSEVKPGDLVVVRQGERIPVDGYVVQGKAYVDESV 338
Query: 244 LTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKF 303
TGE +P K GD +L+G + +G L + TR ++ + RI L+ + A K ++
Sbjct: 339 FTGEPIPVEKKPGDLVLAGSMVSSGWLHISATRTSGDTAIDRIARLIAYSQAGKMDIQRL 398
Query: 304 ITRFAHYYTPAVVGIATLIATVPPLVFKESFTSWVYRALVILVISCPCALVLSIPLGYFG 363
R + + AV+ IA+L T +F + + RA + +ISCPCAL L+ P
Sbjct: 399 ADRVSGMFFWAVLCIASLTFTA--WLFLGGLETAIIRAASVFLISCPCALGLATPTASSA 456
Query: 364 GIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFA 423
G+G AA+ GIL++ + L ASIV FDKTGTLT G+ +V +E +G++E+EIL A
Sbjct: 457 GVGVAARAGILVRNVVAFERLAKASIVVFDKTGTLTLGMPRVAAVEAVDGYSEKEILELA 516
Query: 424 ALAEAHSNHPIAKAIREAYGKEINEA--EITEYEEIAGHGVRARIDSVEVMVGNDKLLHR 481
A AE S HP+A+AI +AY + + E G GV A + V+VGN K++
Sbjct: 517 ASAEKWSEHPLARAIIDAYMEVAGRGPEDPDNAEVFPGMGVYAEVGGRSVVVGNRKIMDG 576
Query: 482 SNIEHDTCKV--------KGTIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKV 533
++ T + T V IDG+ AG I I DE + +A V L++LG+ KV
Sbjct: 577 FEVDIKTLEKIAEEWQSRGATTVFVAIDGKPAGVIAIRDEPRPEARETVDWLEKLGL-KV 635
Query: 534 VMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPV 593
+M+TGDS A IA++L ++ + A + PE K ++I +L+K KG+ +V VGDG+NDAP
Sbjct: 636 MMLTGDSEGTARAIARELDIEEYRAGVSPEGKAEVIRELQK-KGH-VVVMVGDGVNDAPS 693
Query: 594 LARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFAL--GV 651
LARADVG+A+ A +D ++E D+V++ ++P A+ I+RKT + N+ +A V
Sbjct: 694 LARADVGIAV-ANATDVSVEAGDIVLIKGDLRRVPLAVVISRKTYNTIKFNLFWAFIYNV 752
Query: 652 KLAFIGLGIFGKA 664
L + G F A
Sbjct: 753 TLIPVAAGAFAWA 765
>emb|CAB66270.1| (AL136519) probable cation-transporting P-type ATPase.
[Streptomyces coelicolor A3(2)]
Length = 760
Score = 312 bits (791), Expect = 8e-84
Identities = 233/743 (31%), Positives = 366/743 (48%), Gaps = 70/743 (9%)
Query: 5 KLKLEGLDCASCAYEIEEALRKEGFKFAVVNFATKEAIIE-----------GDIEKAKEV 53
+L + G+ CASCA +E+ L + A VN+AT++A + + K
Sbjct: 25 ELLIGGMTCASCAARVEKKLNRMDGVTATVNYATEKARVSYPATTGVADLIATVVKTGYT 84
Query: 54 IKKVEPDVEVVEEVHIHDHAHGEFEK-------RTIYFIGISLVLFTIGILMRYYYAIDN 106
++ P E +E + G+ R + + L + + M DN
Sbjct: 85 AEEPAPPPEPADEAGAGERGTGDGGSDPELSALRQRLLVSVLLAAPVVLLAMVPALQFDN 144
Query: 107 TLVFGLFLAS-YLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAF------------- 152
L LA+ ++ G A L + L+++ T+ AF
Sbjct: 145 WQWLSLTLAAPVVVWGGLPFHRAAWTGLRHGAATMDTLVSLGTLAAFGWSLWALFFGDAG 204
Query: 153 ---------LIKEYPEGVA---------VMLFYVIGEFLQDMAVDKSRRSIKALLALKAE 194
L +G + V F ++G +L+ + ++ +++AL+ L A+
Sbjct: 205 MPGMRHGFDLTVSRTDGTSAIYLEAAAGVTAFLLLGRWLEARSKRRAGAALRALMELGAK 264
Query: 195 YANLVRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVK 254
++R G V++ L VGD +V+PGEK+ DG + EG S+VD S LTGES+P V
Sbjct: 265 DVAVLRAGREVRIPVARLAVGDRFVVRPGEKIATDGTVAEGASAVDASLLTGESVPVDVA 324
Query: 255 EGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPA 314
GD + +N G L V TR +++ ++R+ +LVE+A + KA+ ++ R + + P
Sbjct: 325 VGDTVTGATVNAGGRLVVEATRVGADTQLARMAKLVEDAQSGKAQVQRLADRISGIFVPV 384
Query: 315 VVGIATLIATVPPLVFKESFTSWVYRALV-ILVISCPCALVLSIPLGYFGGIGRAAKEGI 373
V+ IA AT + T + A V +L+I+CPCAL L+ P G GR A+ GI
Sbjct: 385 VLLIA--FATFGGWLGATGDTVAAFTAAVAVLIIACPCALGLATPTALLVGTGRGAQLGI 442
Query: 374 LIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHP 433
LIKG L+ + V DKTGT+T G + ++ G EEE+LR A E S HP
Sbjct: 443 LIKGPEVLENTRRVDTVVLDKTGTVTTGRMTLHEVYAAEGTDEEELLRLAGAVEHASEHP 502
Query: 434 IAKAIREAYGKEINEAEIT---EYEEIAGHGVRARIDSVEVMVG--NDKLLHRSNIEHDT 488
+A+AI A G E + ++E + G G RAR+ EV VG +D L + D
Sbjct: 503 VARAI--AAGAEARLGTLPGAEDFENVPGRGARARVAGHEVAVGRLHDTLPPEVSRARDE 560
Query: 489 CKVKGTIAHVV-IDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEI 547
+ +G A VV DG G + ++D +KE + AV L+RLG+ V++ TGD+R VAE +
Sbjct: 561 AEQRGRTAVVVGWDGAARGVLAVADAVKETSAEAVAGLRRLGLTPVLL-TGDNRRVAESV 619
Query: 548 AKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLV-FVGDGINDAPVLARADVGVAMGAL 606
A +G+D AE+LPEDKV ++E+L E G+ V VGDG+NDA LA AD+G+AMG
Sbjct: 620 AAAVGIDEVIAEVLPEDKVAVVERLRAE---GRTVAMVGDGVNDAAALATADLGLAMGT- 675
Query: 607 GSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGLGIFGKATM 666
G+DAAIE D+ ++ AI+++R+T + N+++A G +A + L G +
Sbjct: 676 GTDAAIEAGDLTLVRGDLRVAADAIRLSRRTLATIKGNLVWAFGYNVAALPLAAAG---L 732
Query: 667 WEAVFADVGVALIAVFNAMRVLR 689
+ A +A +VF LR
Sbjct: 733 LNPMIAGAAMAFSSVFVVTNSLR 755
>pir||F83156 probable metal transporting P-type ATPase PA3920 [imported] -
Pseudomonas aeruginosa (strain PAO1)
>gi|9950104|gb|AAG07307.1|AE004809_7 (AE004809) probable
metal transporting P-type ATPase [Pseudomonas
aeruginosa]
Length = 792
Score = 310 bits (785), Expect = 4e-83
Identities = 213/705 (30%), Positives = 357/705 (50%), Gaps = 68/705 (9%)
Query: 5 KLKLEGLDCASCAYEIEEALRK-EGFKFAVVNFATKEAIIE----GDIEKAKEVIKKVEP 59
+L +EG+ CASC +E AL+K G + VN A++ A +E D + + +++
Sbjct: 76 ELSIEGMTCASCVGRVERALKKVPGVREVSVNLASERAHLELLGAVDSQALLQAVEQAGY 135
Query: 60 DVEVVEEVHIH-DHAHGEFEKRTIYFIGISLVLFTIGILMRYYYA------------IDN 106
+++ D A + + I L+ + + M +A +
Sbjct: 136 KARLLDAGQPRQDDAERRLRRERWWVIAALLLALPLVLPMLVEWAGLHWMLPPWAQFLLA 195
Query: 107 TLVFGLFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEY-----PEG- 160
T V + A + +S W+ +K+ N + L+A+ T + + Y P G
Sbjct: 196 TPVQFVIGARFYVSAWRAVKAGAGNM--------DLLVALGTSAGYGLSVYLWLTAPPGH 247
Query: 161 ---------VAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEE 211
V+ ++G++L+ A ++ +I+AL AL+ E A +RDG +V E
Sbjct: 248 MPHLYFEASTVVIALILLGKYLESRAKRQTASAIRALEALRPERAVRLRDGREEEVAIAE 307
Query: 212 LKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLK 271
L++GD ++V+PGE+ PVDG +++G+S D + +TGES+P GD++ G IN G L
Sbjct: 308 LRLGDEVVVRPGERFPVDGEVLDGSSHADEALITGESLPVPKAPGDKVTGGAINGEGRLL 367
Query: 272 VRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFK 331
+R T E+ +++I+ LVE+A A KA +K + + + + P V+ IA L+ LV
Sbjct: 368 LRTTALGGETVLAKIIRLVEDAQAAKAPIQKLVDKVSQVFVPVVILIA-LVTLGAWLVAG 426
Query: 332 ESFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVA 391
+ A+ +LVI+CPCAL L+ P G G AA+ GILIK + L+ + VA
Sbjct: 427 VGLEQALVNAVAVLVIACPCALGLATPTAIMAGTGVAARHGILIKDAESLEVAHAVTSVA 486
Query: 392 FDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYG-KEINEAE 450
FDKTGTLT G ++ + G +E++LR A + S HP+AKA+ E +++
Sbjct: 487 FDKTGTLTSGRPQIIHL---GGDDQEQLLRLAGALQRGSEHPLAKAVLERCAERDLEVPP 543
Query: 451 ITEYEEIAGHGVRARIDSVEVMVGNDKLLHRSNIEHDTC-----------KVKGTIAHVV 499
+ + ++G G++ ++ + +GN +LL ++ + + +
Sbjct: 544 VNASQALSGRGIQGEVEGRRLALGNRRLLDEQELKPGALASAAADWEAEGRTLSWLLELA 603
Query: 500 IDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAE 559
+ + G D +K+ A AV+ L+ + ++TGD+R A +AK LG+D +AE
Sbjct: 604 PEKRVLGLFAFGDSLKDGAAEAVEALRGRDIHSH-LITGDNRGSAAVVAKALGIDDVHAE 662
Query: 560 LLPEDKVKIIEKLEKEKGNGKLV-FVGDGINDAPVLARADVGVAMGALGSDAAIETADVV 618
+LP DK + +L KG G++V VGDGINDAP LA ADVG+AMG G+D A+ A +
Sbjct: 663 VLPADKAATVAEL---KGRGRVVAMVGDGINDAPALAAADVGIAMGG-GTDVAMHAAGIT 718
Query: 619 IMDDKPSKLPKAIQIARKT-----QRIVWENIIFALGVKLAFIGL 658
+M P +P A+ I+R+T Q + W I +G+ LA GL
Sbjct: 719 LMRGDPRLVPAALDISRRTYAKIRQNLFWAFIYNVIGIPLAAFGL 763
>pir||F83342 probable cation-transporting P-type ATPase PA2435 [imported] -
Pseudomonas aeruginosa (strain PAO1)
>gi|9948481|gb|AAG05823.1|AE004670_11 (AE004670)
probable cation-transporting P-type ATPase [Pseudomonas
aeruginosa]
Length = 661
Score = 303 bits (769), Expect = 3e-81
Identities = 204/621 (32%), Positives = 343/621 (54%), Gaps = 37/621 (5%)
Query: 87 ISLVLFTIGILMR----YYYAIDNTLVFGLFL--ASYLI------SGWKVLKSAIVNSLN 134
+SL + +G+L+ + A D V + L AS L+ S W L+ SL+
Sbjct: 39 LSLAMLALGLLLLGLAWRWLAADQAGVSQILLGVASLLVALPVARSAWDSLRHP---SLH 95
Query: 135 GNVFDENFLIAVATIGAFLIKEYPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAE 194
G V D+ LIA+A +GA+ + + + + G L++ +V S+ +I AL L
Sbjct: 96 G-VTDQ--LIALAMLGAWASGDLLTAALLPIIMIFGHVLEERSVIGSQEAIAALGELTRS 152
Query: 195 YANLVR-DGTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTV 253
+A + DG++ +V L+ GD + V+ G++VP DG +++G +S+DT+ +TGES+P V
Sbjct: 153 HARRIEADGSLSEVDNASLRPGDQVEVRAGDRVPADGRVLQGQASLDTAPITGESVPLEV 212
Query: 254 KEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTP 313
G E+ G INL GLL++ +TR ST+ +++ L++ A K + + R+A Y
Sbjct: 213 APGMEVYGGAINLDGLLRIEITRTGEASTLGKVIGLMQQAERAKPPITRLLERYAGQYML 272
Query: 314 AVVGIATLIATVPPLVFKESFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGI 373
V+ LIA V V T+ L +LV +CPCALVLS P GI AA+ GI
Sbjct: 273 LVL----LIAAVTWFV-----TNDAQAMLAVLVAACPCALVLSAPATAIAGIAVAARHGI 323
Query: 374 LIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHP 433
LI+ S +L+ L D + + DKTGTLT G ++ + + E +LR AA A S+HP
Sbjct: 324 LIRSSAFLEELADLTSLVVDKTGTLTHGSLRLQALRLADAAEEASVLRLAASLGAASSHP 383
Query: 434 IAKAIREAYGKEINEAEITEYEEIAGHGVRARIDSVEVMVGNDKLLHRSNIE-HDTCKVK 492
+++A+ + +++ E G GV AR + E +G +L + I+ + + +
Sbjct: 384 VSRALAALAAHDAYH-PLSDIRERQGFGVVARTAAGEAALGRPELFQQLGIDASEVPEHE 442
Query: 493 GTIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLG 552
G IA + +DG++ G+++++D ++ +A A+ +L+ LG+ + +++TGD R VA+ +AKQ+G
Sbjct: 443 GPIAGIALDGRFLGWLLLADSVRAEAAEALADLRELGLGRQLLLTGDRRAVADAVAKQVG 502
Query: 553 LDGFYAELLPEDKVKIIEKLEKEKGNG-KLVFVGDGINDAPVLARADVGVAMGALGSDAA 611
+ A+ LPEDK++ ++ E G+G + + VGDGIND+ L VGVAMGA G+D A
Sbjct: 503 IRQLVAQALPEDKLR---QVGAEIGSGFRPMVVGDGINDSLALKAGVVGVAMGAGGADIA 559
Query: 612 IETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFI---GLGIFGKATMWE 668
+ +AD+V++ +L ++++R+ +R + N+ LG LA + G+ G A
Sbjct: 560 LASADIVLIGSDLRRLGTCVRLSRQCRRTLQVNVAIGLGWTLAIVAAAAFGLLGAAGAMV 619
Query: 669 AVFADVGVALIAVFNAMRVLR 689
A L+ + NA R+LR
Sbjct: 620 AALLHNLSTLLVLGNAGRLLR 640
>pir||A81742 cation-transporting ATPase, E1-E2 family TC0100 [imported] -
Chlamydia muridarum (strain Nigg)
>gi|7190135|gb|AAF38980.1| (AE002277)
cation-transporting ATPase, E1-E2 family [Chlamydia
muridarum]
Length = 659
Score = 300 bits (761), Expect = 3e-80
Identities = 211/619 (34%), Positives = 322/619 (51%), Gaps = 26/619 (4%)
Query: 87 ISLVLFTIGILMRYYYAIDNTLVFGLFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAV 146
ISL L+ IG L+ ++ L L + ++ ++G L + + LN V + + L+
Sbjct: 49 ISLALY-IGSLLSHWTGYQ-PLSSLLLILTFFLAGTPALVKSFEDILNKTV-NIDILMTS 105
Query: 147 ATIGAFLIKEYPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVR-DGTVV 205
A G+ I EG +++ + I E L M K++ ++ +L L A +V+ DG++
Sbjct: 106 AAFGSIFIGGALEGALLLVLFAISESLGSMVSGKAKSTLASLKHLAPTVAWVVQQDGSLQ 165
Query: 206 KVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMIN 265
K+ + +KVG++I VK GE VP+DG II+G SS++ LTGE +P++ GD + +G N
Sbjct: 166 KILVQNVKVGEVIRVKSGEVVPLDGEIIQGASSINLMHLTGEKIPKSCNIGDTVPAGAHN 225
Query: 266 LTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATV 325
L G ++V R +EST++ I+ LV A + K K ++ + R++ Y + I+ IA
Sbjct: 226 LEGSFDLKVLRIGAESTIAHIINLVIQAQSAKPKLQQRLDRYSSTYALTIFAISASIAIG 285
Query: 326 PPLVFKESFT---SWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLD 382
L F S YRAL L+ + PCAL+++IP+ Y I AK G+L+KG LD
Sbjct: 286 GSLFTTLPFLGPDSAFYRALAFLIAASPCALIIAIPIAYLSTINACAKHGVLLKGGVVLD 345
Query: 383 ALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALA--EAHSNHPIAKAI-R 439
L + V DKTGTLT G E F E L ++ + E S+HPIA+AI
Sbjct: 346 RLVSCNSVVMDKTGTLTTGDLTCCGCED---FGPESPLFYSYVLAMEQSSSHPIAQAIVN 402
Query: 440 EAYGKEINEAEITEYEEIAGHGVRARIDSVEVMVGNDKLLHRSNIEH---------DTCK 490
K++ T+ I G GV+ + + VG R E +
Sbjct: 403 YLTEKQVLPLPATQCTTIPGEGVQGEFNGDQAFVGRVSTALRYVPEEYREQLRERAQQAQ 462
Query: 491 VKGTIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQ 550
+G + GQ D + DA V LK+ G V M+TGD R AE A+
Sbjct: 463 ARGETCSIACSGQRVSLFYFRDAPRHDAADIVAYLKKNGY-PVCMLTGDHRISAENTAQL 521
Query: 551 LGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDA 610
LG+D + +L P++K+ I++L K + +++ VGDGINDAP LA+A VG+AMG GS
Sbjct: 522 LGIDEVFYDLTPDNKLSKIQELAKTR---QIMMVGDGINDAPALAQATVGIAMGEAGSAT 578
Query: 611 AIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGLGIFGKATMWEAV 670
AIE ADVV+++ S LP I+ A+KT+RIV +N+ AL + L G G +W AV
Sbjct: 579 AIEAADVVLLNQGLSSLPWLIKKAKKTRRIVSQNLALALSIILFISGPASMGIIPLWLAV 638
Query: 671 FADVGVALIAVFNAMRVLR 689
G +I NA+R+L+
Sbjct: 639 ILHEGSTVIVGLNALRLLK 657
>sp|P37279|ATCS_SYNP7 CATION-TRANSPORTING ATPASE PACS >gi|480354|pir||S36741 probable
copper-transporting ATPase (EC 3.6.1.-) pacS -
Synechococcus sp >gi|435125|dbj|BAA03907.1| (D16437)
PacS [Synechococcus sp.]
Length = 747
Score = 300 bits (760), Expect = 3e-80
Identities = 223/711 (31%), Positives = 366/711 (51%), Gaps = 74/711 (10%)
Query: 6 LKLEGLDCASCAYEIEEALRK-EGFKFAVVNFA------------TKEAIIEGDIEKAK- 51
L L G+ CA+CA IE ++ G + VNF T+ A I+ IE A
Sbjct: 7 LTLRGMGCAACAGRIEALIQALPGVQECSVNFGAEQAQVCYDPALTQVAAIQAAIEAAGY 66
Query: 52 EVIKKVEPDVEVVEEVHIHDHAHGEFE-KRTIYFIGISLVLFTIGIL-MRYYYAIDNT-- 107
+P VE H A + + + ++ G+ L IG L M +I
Sbjct: 67 HAFPLQDPWDNEVEAQERHRRARSQRQLAQRVWVSGLIASLLVIGSLPMMLGISIPGIPM 126
Query: 108 ------LVFGLFLA------SYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIK 155
L GL L S+ I+ WK + N + L+AV T AFL
Sbjct: 127 WLHHPGLQLGLTLPVLWAGRSFFINAWKAFRQ--------NTATMDTLVAVGTGAAFLYS 178
Query: 156 ------------------EYPEGVAVML-FYVIGEFLQDMAVDKSRRSIKALLALKAEYA 196
Y E +AV++ ++G L++ A ++ +I+ L+ L+A+ A
Sbjct: 179 LAVTLFPQWLTRQGLPPDVYYEAIAVIIALLLLGRSLEERAKGQTSAAIRQLIGLQAKTA 238
Query: 197 NLVRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEG 256
++R G + + E++V D + V+PGEKVPVDG +I+G S+VD S +TGES+P + G
Sbjct: 239 RVLRQGQELTLPITEVQVEDWVRVRPGEKVPVDGEVIDGRSTVDESMVTGESLPVQKQVG 298
Query: 257 DEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVV 316
DE++ +N TG L +R TR E+ +++I++LV+ A A KA ++ + ++ PAV+
Sbjct: 299 DEVIGATLNKTGSLTIRATRVGRETFLAQIVQLVQQAQASKAPIQRLADQVTGWFVPAVI 358
Query: 317 GIATLIATVPPLVFKESFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIK 376
IA ++ + + + T + A+ +++I+CPCAL L+ P G G+ A+ GILIK
Sbjct: 359 AIA-ILTFLLWFNWIGNVTLALITAVGVMIIACPCALGLATPTSIMVGTGKGAEYGILIK 417
Query: 377 GSNYLDALKDASIVAFDKTGTLTKGVFKVTK-IETRNGFTEEEILRFAALAEAHSNHPIA 435
+ L+ + V DKTGTLT+G VT + + ++ +L +AA E +S HP+A
Sbjct: 418 SAESLELAQTIQTVILDKTGTLTQGQPSVTDFLAIGDRDQQQTLLGWAASLENYSEHPLA 477
Query: 436 KAI-REAYGKEINEAEITEYEEIAGHGVRARIDSVEVMVGNDKLLHRSNIE--------H 486
+AI R + I + +T++E I G GV+ +++ + + +G + L IE
Sbjct: 478 EAIVRYGEAQGITLSTVTDFEAIPGSGVQGQVEGIWLQIGTQRWLGELGIETSALQNQWE 537
Query: 487 DTCKVKGTIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEE 546
D T+ V DG + I+D++K + V+ L+RLG+ +VVM+TGD+R A+
Sbjct: 538 DWEAAGKTVVGVAADGHLQAILSIADQLKPSSVAVVRSLQRLGL-QVVMLTGDNRRTADA 596
Query: 547 IAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLV-FVGDGINDAPVLARADVGVAMGA 605
IA+ +G+ AE+ P+ K + +L+ G++V VGDGINDAP LA+ADVG+A+G
Sbjct: 597 IAQAVGITQVLAEVRPDQKAAQVAQLQ---SRGQVVAMVGDGINDAPALAQADVGIAIGT 653
Query: 606 LGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFI 656
G+D AI +D+ ++ + AIQ++R T + +N+ FA +A I
Sbjct: 654 -GTDVAIAASDITLISGDLQGIVTAIQLSRATMTNIRQNLFFAFIYNVAGI 703
>pir||B71479 probable metal transport p-type ATPase - Chlamydia trachomatis
(serotype D, strain UW3/Cx) >gi|3329184|gb|AAC68322.1|
(AE001343) Metal Transport P-type ATPase [Chlamydia
trachomatis]
Length = 659
Score = 299 bits (757), Expect = 8e-80
Identities = 210/621 (33%), Positives = 322/621 (51%), Gaps = 30/621 (4%)
Query: 87 ISLVLFTIGILMRY--YYAIDNTLVFGLFLASYLISGWKVLKSAIVNSLNGNVFDENFLI 144
ISL L+ +L + Y A+ + L+ + ++ ++G L + + L+ V + + L+
Sbjct: 49 ISLALYLGSLLSHWIGYQALSSLLL----ILTFFLAGTPALIKSFEDILDRTV-NIDILM 103
Query: 145 AVATIGAFLIKEYPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVR-DGT 203
A G+ I EG +++ + I E L M K++ ++ +L L A +V+ DG+
Sbjct: 104 TSAAFGSIFIGGALEGALLLVLFAISESLGAMVSGKAKSTLASLKHLAPTVAWVVQQDGS 163
Query: 204 VVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGM 263
+ KV + +KVG+II VK GE VP+DG II+G SS++ LTGE +P++ GD I +G
Sbjct: 164 LQKVLVQNVKVGEIIRVKSGEVVPLDGKIIQGASSINLMHLTGEKIPKSCGIGDTIPAGA 223
Query: 264 INLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIA 323
NL G ++V R +EST++ I+ LV A + K K ++ + R++ Y + I+ IA
Sbjct: 224 HNLEGSFDLQVLRIGAESTIAHIINLVVQAQSSKPKLQQRLDRYSSTYALTIFAISACIA 283
Query: 324 TVPPLVFKESFT---SWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNY 380
L F S YRAL L+ + PCAL+++IP+ Y I AK G+L+KG
Sbjct: 284 IGGSLFTTLPFLGPDSAFYRALAFLIAASPCALIIAIPIAYLSAINACAKHGVLLKGGVV 343
Query: 381 LDALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALA--EAHSNHPIAKAI 438
LD L + V DKTGTLT G + E F E L ++ + E S+HPIA+AI
Sbjct: 344 LDRLVSCNSVVMDKTGTLTTGDLTCSGCED---FGPESPLFYSCVLAMEQSSSHPIAQAI 400
Query: 439 -REAYGKEINEAEITEYEEIAGHGVRARIDSVEVMVGNDKLLHRSNIEH---------DT 488
K++ T+ I G GV + + VG R E
Sbjct: 401 VNYLTEKQVRSLPATQCTTIPGEGVSGEFNGEQAFVGRVSTALRYVPEEYREQLRERAQQ 460
Query: 489 CKVKGTIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIA 548
+ +G + G+ D + DA V LK+ G V M+TGD R AE A
Sbjct: 461 AQERGDTCSIACLGKRVSLFYFRDVPRHDAADIVSYLKKNGY-PVCMLTGDHRISAENTA 519
Query: 549 KQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGS 608
+ LG+D + +L P++K+ I++L K + +++ +GDGINDAP LA+A VG+AMG GS
Sbjct: 520 RLLGIDEVFYDLTPDNKLSKIQELAKSR---QIMMIGDGINDAPALAQATVGIAMGEAGS 576
Query: 609 DAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGLGIFGKATMWE 668
AIE ADVV+++ S LP I A+KT+RIV +N+ AL + L G G +W
Sbjct: 577 ATAIEAADVVLLNQGLSSLPWLIDKAKKTRRIVSQNLALALAIILFISGPASMGVIPLWL 636
Query: 669 AVFADVGVALIAVFNAMRVLR 689
AV G +I NA+R+L+
Sbjct: 637 AVILHEGSTVIVGLNALRLLK 657
>emb|CAB96031.1| (AL360055) putative metal transporter ATPase [Streptomyces
coelicolor A3(2)]
Length = 753
Score = 298 bits (756), Expect = 1e-79
Identities = 223/743 (30%), Positives = 365/743 (49%), Gaps = 69/743 (9%)
Query: 5 KLKLEGLDCASCAYEIEEALRKEGFKFAVVNFATKEAIIE--GDIEKAKEVIKKVEPDVE 62
+L + G+ CASCA IE+ L + A VN+AT++A + GD+ E+I VE
Sbjct: 13 ELTIGGMTCASCAARIEKKLNRMEGVTATVNYATEKAKVSYAGDVS-VPELIATVEATGY 71
Query: 63 VVEEVHIHDHAHGE-------------FEKRTIYFIGISLVLFTIGILMRYYYAIDNTLV 109
E G +R + + +++ + + ++ + L
Sbjct: 72 TAREPEPVRTGAGSGPGGAETVDELRPLRERLVTSVVLAVPVIAMAMVPALQFEYWQWLS 131
Query: 110 FGLFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKE------------- 156
L + W K+A N+ +G + LI+V T AFL
Sbjct: 132 LTLAAPVVTYAAWPFHKAAFTNARHGAATMDT-LISVGTSAAFLWSLWALFLGTAGTPGM 190
Query: 157 -----------------YPEGVA-VMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANL 198
Y E A V F + G + + + K+ ++KALL L A+ +
Sbjct: 191 THPFELTIARGDGSGNIYLEAAAGVTAFILAGRYFEARSKRKAGAALKALLELGAKDVTV 250
Query: 199 VRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDE 258
VR G ++ +L VGD +V+PGEK+ DG ++EG+S+VD S LTGES+P V GD
Sbjct: 251 VRGGREERIPVGDLTVGDRFLVRPGEKIATDGTVVEGSSAVDASMLTGESVPVEVAAGDG 310
Query: 259 ILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGI 318
+ +N G L V TR +++ ++R+ LVE+A KA ++ R + + P V+ +
Sbjct: 311 VTGATVNAGGRLVVEATRVGADTQLARMARLVEDAQNGKAAAQRLADRISGVFVPVVIAL 370
Query: 319 ATLIATVPPLVFKESFTSWVYRALV-ILVISCPCALVLSIPLGYFGGIGRAAKEGILIKG 377
A +AT+ + S + + A V +L+I+CPCAL L+ P G GR A+ GILIKG
Sbjct: 371 A--LATLGFWLGNGSGPAAAFTAAVAVLIIACPCALGLATPTALMVGTGRGAQLGILIKG 428
Query: 378 SNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKA 437
L++ + + DKTGT+T G + + T +G E ++LR A E S HPIA+A
Sbjct: 429 PEVLESTRKVDTIVLDKTGTVTTGRMTLLAVHTADGTDEADVLRLAGALEHASEHPIAQA 488
Query: 438 IREAYGKEINEAEITE-YEEIAGHGVRARIDSVEVMVGNDKLLHRSNIEHDT----CKVK 492
+ + E + + G GV+ ++ V+VG +KLL +E K +
Sbjct: 489 VAAGATERAGALPTPEDFANVPGLGVQGVVEGHAVLVGREKLLAEWAMELPAELGRAKTR 548
Query: 493 G-----TIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEI 547
T V DG+ + ++D +K+ + AV L+ LG+ +++TGD+R VAE +
Sbjct: 549 AEAAGRTAIAVAWDGEARAVLEVADAVKDTSGEAVTRLRALGLTP-ILLTGDNRAVAEAV 607
Query: 548 AKQLGLDGFY--AELLPEDKVKIIEKLEKEKGNGKLV-FVGDGINDAPVLARADVGVAMG 604
A ++G+ + AE++PEDKV ++++L+ G G+ V VGDG+NDA LA+AD+G+AMG
Sbjct: 608 AAEVGIAPAHVIAEVMPEDKVAVVKRLQ---GEGRSVAMVGDGVNDAAALAQADLGLAMG 664
Query: 605 ALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGLGIFGKA 664
G+DAAIE D+ ++ AI++AR+T + N+ +A +A + L G
Sbjct: 665 T-GTDAAIEAGDLTLVRGDLRAAADAIRLARRTLGTIKSNLFWAFAYNVAALPLAAAGLL 723
Query: 665 TMWEAVFADVGVALIAVFNAMRV 687
A A ++ V N++R+
Sbjct: 724 NPMIAGAAMAFSSVFVVGNSLRL 746
>sp|Q10876|CTPA_MYCTU CATION-TRANSPORTING P-TYPE ATPASE A >gi|7436396|pir||D70750
probable ctpA protein - Mycobacterium tuberculosis
(strain H37RV) >gi|1405763|emb|CAA98928.1| (Z74410) ctpA
[Mycobacterium tuberculosis]
Length = 761
Score = 295 bits (748), Expect = 9e-79
Identities = 215/731 (29%), Positives = 362/731 (49%), Gaps = 58/731 (7%)
Query: 5 KLKLEGLDCASCAYEIEEALRKEGFKFAVVNFATKEAIIEG----DIEKAKEVIKKVEPD 60
+L++ G+ C++CA+ +E L K A VNF T+ A I+ D + +++
Sbjct: 17 QLRISGMSCSACAHRVESTLNKLPGVRAAVNFGTRVATIDTSEAVDAAALCQAVRRAGYQ 76
Query: 61 VEV-VEEVHIHDHAHGEFEKRTIYFIGISLVLFT--------IGILMRYYYAIDNTLVFG 111
++ ++ + ++ + + I+ VLF G++ + ++
Sbjct: 77 ADLCTDDGRSASDPDADHARQLLIRLAIAAVLFVPVADLSVMFGVVPATRFTGWQWVLSA 136
Query: 112 LFLASYLISGWKVLKSAIVNSLNGNVFDENFL---IAVATIGAF---------------- 152
L L + W + A+ N+ + E + I ATI +
Sbjct: 137 LALPVVTWAAWPFHRVAMRNARHHAASMETLISVGITAATIWSLYTVFGNHSPIERSGIW 196
Query: 153 --------LIKEYPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKA-EYANLVRDGT 203
+ E GV V F ++G + + A ++ +++AL AL A E A L+ DG+
Sbjct: 197 QALLGSDAIYFEVAAGVTV--FVLVGRYFEARAKSQAGSALRALAALSAKEVAVLLPDGS 254
Query: 204 VVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGM 263
+ + +ELK +V+PG+ V DG+ ++G+++VD SA+TGE+ P V+ G +++ G
Sbjct: 255 EMVIPADELKEQQRFVVRPGQIVAADGLAVDGSAAVDMSAMTGEAKPTRVRPGGQVIGGT 314
Query: 264 INLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIA 323
L G L V +++ + ++ LVE A A+KA ++ R + + PAV+ IA L A
Sbjct: 315 TVLDGRLIVEAAAVGADTQFAGMVRLVEQAQAQKADAQRLADRISSVFVPAVLVIAALTA 374
Query: 324 TVPPLVFKESFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDA 383
L+ V AL +LVI+CPCAL L+ P GR A+ GI +KG L+A
Sbjct: 375 -AGWLIAGGQPDRAVSAALAVLVIACPCALGLATPTAMMVASGRGAQLGIFLKGYKSLEA 433
Query: 384 LKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYG 443
+ V FDKTGTLT G +V+ + G+ +++L AA EA S H +A AI A
Sbjct: 434 TRAVDTVVFDKTGTLTTGRLQVSAVTAAPGWEADQVLALAATVEAASEHSVALAIAAA-- 491
Query: 444 KEINEAEITEYEEIAGHGVRARIDSVEVMVGNDKLLHRSNIEHDTCKVK-------GTIA 496
+T++ I G GV + V VG + S+ + + T
Sbjct: 492 -TTRRDAVTDFRAIPGRGVSGTVSGRAVRVGKPSWIGSSSCHPNMRAARRHAESLGETAV 550
Query: 497 HVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGF 556
V +DG+ G I ++D +K+ A AV L G+R +++TGD+ + A +A ++G+D
Sbjct: 551 FVEVDGEPCGVIAVADAVKDSARDAVAALADRGLR-TMLLTGDNPESAAAVATRVGIDEV 609
Query: 557 YAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETAD 616
A++LPE KV +IE+L +++G+ + VGDGIND P LARAD+G+A+G G+D AI AD
Sbjct: 610 IADILPEGKVDVIEQL-RDRGH-VVAMVGDGINDGPALARADLGMAIGR-GTDVAIGAAD 666
Query: 617 VVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGLGIFGKATMWEAVFADVGV 676
++++ D +P A+ +AR T R V N+++A G +A I + G A A
Sbjct: 667 IILVRDHLDVVPLALDLARATMRTVKLNMVWAFGYNIAAIPVAAAGLLNPLVAGAAMAFS 726
Query: 677 ALIAVFNAMRV 687
+ V N++R+
Sbjct: 727 SFFVVSNSLRL 737
>pir||G75270 cation-transporting ATPase - Deinococcus radiodurans (strain R1)
>gi|6460273|gb|AAF11997.1|AE002075_1 (AE002075)
cation-transporting ATPase [Deinococcus radiodurans]
Length = 847
Score = 295 bits (748), Expect = 9e-79
Identities = 229/786 (29%), Positives = 378/786 (47%), Gaps = 135/786 (17%)
Query: 10 GLDCASCAYEIEEALRK-EGFKFAVVNFATKEAIIE---GDIEKAKEVIKKVEPDVEVVE 65
G+ CA+C +E AL K +G A VN AT+ A + + A+ V +V E
Sbjct: 78 GMTCAACVGRVERALNKTDGVLDASVNLATERASVRYLPASVSPAELKSAVVNAGYDVPE 137
Query: 66 EVHIHDHAHGEFE-------------KRTIYFIGI-SLVLFTIGILMRYYYAIDNTL--- 108
E A E +R++ F + S+ L + ++ Y + + L
Sbjct: 138 E---QTQAASRLELERARKAEELAGLRRSLTFSAVFSVPLLLLSMVPMLYPLLHHWLLGT 194
Query: 109 -------VFGLFLAS---------YLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAF 152
V L LA+ + +GW L+ D N L+ + T AF
Sbjct: 195 LGERAMNVLMLLLAAPVQFGPGLRFYRTGWAALRHRSP--------DMNTLVMLGTSAAF 246
Query: 153 LI--------KEYPEG---------VAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEY 195
+ +P G V+ ++G++ + +A +S +++ LL L+ +
Sbjct: 247 FYSLAVTLWPQLFPAGSRHVYFEASAVVITLILLGKYFEALAKGRSSEAMRTLLQLQPQS 306
Query: 196 ANLVRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKE 255
A + R VV+V + ++VGD ++V+ GE++PVDG ++ G S VD S LTGES+P
Sbjct: 307 ARVQRGTEVVEVPVDGVRVGDTVLVRSGERLPVDGEVLSGESYVDESMLTGESVPVHKAA 366
Query: 256 GDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAV 315
G ++ G +N TG L R T +++ ++RI+ LVE+A A + + R + P V
Sbjct: 367 GAKVTGGTVNGTGSLTFRATGVGADTALARIIRLVEDAQASRPPIQGLADRVVAQFVPLV 426
Query: 316 VGIATLIATVPPLVFKESFTSWVY------------RALVILVISCPCALVLSIPLGYFG 363
+ IA + +F +W+Y + +L+I+CPCA+ L+ P+
Sbjct: 427 LAIALV-----------TFLAWLYVGGPSALSNALIHTVAVLIIACPCAMGLATPVSIMV 475
Query: 364 GIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTK--IETRNGFTEEEILR 421
G GRAA+ G+L + L+ L +A VA DKTGT+T+GV +VT ++ R + E+LR
Sbjct: 476 GSGRAAQLGVLFRSGAALEGLGEAQTVALDKTGTVTRGVMEVTDVVVDGRWVMGDGELLR 535
Query: 422 FAALAEAHSNHPIAKAIREA------------------YGKEINE-------AEITEYEE 456
AA+AE S HP+A+AI A G+ NE + + ++
Sbjct: 536 LAAIAEGPSEHPLARAIERAATLSPSPLAGEGLAQPGVRGRVTNEPAPSPTLPQPSSFQA 595
Query: 457 IAGHGVRARIDSVEVMVGNDKLLHRSNIEHDTCKVKG--------TIAHVVIDGQYAGYI 508
+ G+G+RA +D V +G + + + + K T +DGQ AG +
Sbjct: 596 LPGYGLRAEVDGRRVEIGAARFMAQLGLPLGELGAKADELAARARTPVFAAVDGQLAGLL 655
Query: 509 VISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKI 568
++D I+E + A++ L G+ V MVTGD+R AE +A++ G++ AE+LPE K +
Sbjct: 656 GVADPIREGSAEAIRTLTAQGL-DVAMVTGDARATAEAVAREAGVNRVLAEVLPEGKAQA 714
Query: 569 IEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLP 628
+ +L ++ ++ FVGDGINDAP LA ADVGVA+G G+D A+ETADV+++ +P
Sbjct: 715 VAEL--QQCGQRVAFVGDGINDAPALAGADVGVAIGT-GTDVAVETADVILLGGDLRSVP 771
Query: 629 KAIQIARKTQRIVWENIIFALGVKLAFIGLGIFGKATMW----EAVFADVGVALIAVF-- 682
A+ ++R R + N+ +A + I + G W V A + L +VF
Sbjct: 772 NAVALSRAVIRNIKLNLFWAFAYNVLLIPVAA-GVLAPWGLGLSPVLAAAAMGLSSVFVM 830
Query: 683 -NAMRV 687
NA+R+
Sbjct: 831 SNALRL 836
>gb|AAD11750.1| (AF067954) putative cation transporting P-type ATPase SilP
[Salmonella typhimurium]
Length = 824
Score = 293 bits (743), Expect = 3e-78
Identities = 193/583 (33%), Positives = 320/583 (54%), Gaps = 31/583 (5%)
Query: 128 AIVNSLNGNVFDENFLIAVATIGAFLIKEYPEGVAVMLFYVIGEFLQDMAVDKSRRSIKA 187
A V S+ VF F + + + + + + ++G+ L+ A +++ +I A
Sbjct: 244 AWVYSVIATVFPSWFPASFRNMDGLVAIYFEAAAVITVLVLLGQVLELRAREQTSGAITA 303
Query: 188 LLALKAEYAN-LVRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTG 246
LL L + A L +DG + E++ GD + ++PGE +PVDG+++EG ++VD S +TG
Sbjct: 304 LLNLAPKTARRLDQDGHETDINAEDVLPGDKLRIRPGESIPVDGIVVEGKTTVDESMVTG 363
Query: 247 ESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITR 306
ESMP T EG+ ++ G IN TG L +R + E+ +SRI+++V +A +A ++
Sbjct: 364 ESMPVTKTEGEPVIGGTINQTGSLIIRAEKVGDETMLSRIVQMVADAQRSRAPIQRMADS 423
Query: 307 FAHYYTPAVVGIATLIATVPPLVF-----KESFTSWVYRALVILVISCPCALVLSIPLGY 361
+ ++ P V+ LIA V +++ + + A+ +L+I+CPCAL L+ P+
Sbjct: 424 VSGWFVPLVI----LIAVVAFMIWSVWGPEPRMAHGLIAAVSVLIIACPCALGLATPMSI 479
Query: 362 FGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILR 421
G+G+ A+ G+LIK + L+ L+ + DKTGTLT+G VT I + N E +LR
Sbjct: 480 MVGVGKGAQAGVLIKNAEALERLEKVDTLVVDKTGTLTEGSPTVTGIISLNPGGETSLLR 539
Query: 422 FAALAEAHSNHPIAKA-IREAYGKEINEAEITEYEEIAGHGVRARIDSVEVMVGNDKLLH 480
A + S HP+ A ++ A K I +T + +G GV ++ V++GN+ +
Sbjct: 540 VTAAVDKGSQHPLGMAVVKAAQEKGIAIPAVTHFNAPSGKGVSGDVEGQRVVIGNELAMQ 599
Query: 481 RSNI-------EHDTCKVKG-TIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRK 532
++I DT +++G T+ +V DG AG I ISD +K A+K L++ G+R
Sbjct: 600 ENSIVIDNQKAVADTLRMEGTTVIYVATDGHLAGLIAISDPVKATTPDALKALRQAGIR- 658
Query: 533 VVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLV-FVGDGINDA 591
+VM+TGD++ AE +A++LG+D A +LP+ K +I +L K +G +V GDG+NDA
Sbjct: 659 IVMLTGDNQLTAEAVARKLGIDEVEAGILPDGKKAVITRL---KASGHVVAMAGDGVNDA 715
Query: 592 PVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIF---- 647
P LA ADVG+AMG G+D AIE+A V ++ L +A ++ T + + +N+ F
Sbjct: 716 PALAAADVGIAMGT-GTDVAIESAGVTLLKGDLMILNRARHLSEITMKNIRQNLFFAFIY 774
Query: 648 -ALGVKLAFIGLGIFGKATMWEAVFADVGVALIAVFNAMRVLR 689
ALGV +A GL + V A +AL +V + LR
Sbjct: 775 NALGVPVA-AGLLYPVYGILLSPVIAAAAMALSSVSVIVNALR 816
>pir||F70425 cation transporting ATPase (E1-E2 family) - Aquifex aeolicus
>gi|2983833|gb|AAC07388.1| (AE000740) cation
transporting ATPase (E1-E2 family) [Aquifex aeolicus]
Length = 679
Score = 291 bits (738), Expect = 1e-77
Identities = 215/708 (30%), Positives = 369/708 (51%), Gaps = 53/708 (7%)
Query: 2 MPRKLKLEGLDCASCAYEIEEALRK-EGFKFAVVNFATKEAIIE--GDIEKAKEVIKKVE 58
M + K+ G+ C +CA IE L++ EG K V+F +E D+ +E++KK+E
Sbjct: 1 MRKAFKVYGMSCVNCARAIEITLKRTEGVKNVNVSFELGRVEVEFDEDLISEEEIVKKIE 60
Query: 59 PDVEVVEEVHIHDHAHGEFEKRTIYFIGISLVLFTIGILMRYYYAIDNTLVFGLFLASYL 118
E+ +++K + +S + F +G M + + + L F L
Sbjct: 61 -------ELGYSVERKKDYDKLFLGLGVLSSLFFLVG--MFFTFPLKYELQFLLSSIVQF 111
Query: 119 ISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAF---------LIKEYP---EGVAVMLF 166
+GWK + A +SL + + L+A+ T GA+ LI P V ++ F
Sbjct: 112 TAGWKFYRGAY-SSLKKGIGSMDTLVALGTTGAYVYSVLSYFNLINSTPFFETNVFLITF 170
Query: 167 YVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIVKPGEKV 226
+G+F+++ A +++ + +K L+ L ++ V+ E+ G+ ++ + GE++
Sbjct: 171 VRLGKFIEEKAKERAVKGLKELVNLSFRKVKVLEGEKEVEKNVREVFKGEKVVYRSGEQI 230
Query: 227 PVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRI 286
+DGVII+G V+ + +TGE +P KEGDE+ SG + G + +VT+ S ++ +
Sbjct: 231 LLDGVIIKGEGLVNEAVITGEPVPILKKEGDEVYSGSVLEKGYIITKVTKTFESSFINTM 290
Query: 287 LELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKESFTSWVYRALVILV 346
+LVE + K K ++ + +HY+ VV I ++I + + V +L +LV
Sbjct: 291 KKLVEESLKEKPKIQRISDKVSHYFVLFVV-ILSVITFLTWFIKTGEINRAVQFSLAVLV 349
Query: 347 ISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVT 406
+SCPCA +++PL GI +A K GIL K + V FDKTGTLT+G KV
Sbjct: 350 VSCPCAFGIAVPLAVSVGIYKAVKRGILPKKGTIFEVAPKVDTVIFDKTGTLTEGKLKVK 409
Query: 407 KIETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKEI-NEAEITEYEEIAGHGVRAR 465
+I E+ E +SNHP+AKA+RE + EA++ EEI G GVR
Sbjct: 410 EIN-----VPEKYFDVLYSMENYSNHPVAKAVREYLKPYVKREAKLEGCEEILGVGVRCG 464
Query: 466 IDSVEVMVGNDKLLHRSNIEHDTCKVK-GTIAHVVIDGQYAGYIVISDEIKEDAHLAVKE 524
E + G +L + N ++ +V GT ++ G I++ D ++++A V+
Sbjct: 465 ----EFIAGKAELWGK-NSQNGVIRVGFGTKDKLI------GEIILEDSVRKEAKEVVEF 513
Query: 525 LKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFV 584
LK G+ V+++TGD+++ A+ IAK+LG+ A + PE+K+K++++L+ EKG K+ V
Sbjct: 514 LKGKGI-NVILLTGDTKENAQRIAKELGIKEVIANVKPEEKLKVVKELQ-EKGR-KVCMV 570
Query: 585 GDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWEN 644
GDG+NDAP LA++D+G+A+ A G+D A + DVVI K S LP+ ++ + R + EN
Sbjct: 571 GDGVNDAPALAQSDLGIAV-AEGTDLAKLSGDVVI--HKLSSLPQVFTLSERVYRKIKEN 627
Query: 645 IIFALGVKLAFIGLG---IFGKATMWEAVFADVGVALIAVFNAMRVLR 689
+A + FI + ++ K + FA + +AL +V + LR
Sbjct: 628 FFWAFAYNVTFIPIAAGVLWSKGIYLKPEFAGLLMALSSVSVVLNTLR 675
>sp|O32619|COPA_HELFE COPPER-TRANSPORTING ATPASE >gi|11267397|pir||T47269
copper-transporting ATPase (EC 3.6.1.-) P-type copA
[validated] - Helicobacter felis
>gi|2660542|emb|CAA05104.1| (AJ001932) copA
[Helicobacter felis]
Length = 732
Score = 290 bits (734), Expect = 4e-77
Identities = 228/731 (31%), Positives = 379/731 (51%), Gaps = 60/731 (8%)
Query: 1 MMPRKLKLEGLDCASCAYEIEEALRKEGFKFAV-VNFATKEAIIEGDIEKA--KEVIKKV 57
M + +EG+ C++C+ IE AL ++ F V V+ +K+A + D +A ++V K++
Sbjct: 1 MTKAQFYIEGMTCSACSSGIERALGRKKFVQEVGVDLISKKAFVVYDENQASLEDVFKQI 60
Query: 58 EPDVEVVEEVHIHDHAHGEFEKRTIYFIGISLVLF---TIGILMRYYYAIDNTLVFGLFL 114
E ++ + + F + + L L T+G+L +A L FL
Sbjct: 61 E---KLGYQPRVATDTPNTFLNPSFLTPNVKLALVLLGTLGVLALSMFA--PLLPLPSFL 115
Query: 115 ASYLISGW-KVLKSAIVNSLNGNVFDENF------------LIAVATIGAFLIK------ 155
+ I+G +++ S +V + N + F LIA+ T A L
Sbjct: 116 KNPFINGIVQLVLSLMVMHMGRNFYVHGFKALWARQPNMDSLIALGTSAALLYSLVLLFR 175
Query: 156 ---------EYPEGVAVMLFYVI-GEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVV 205
Y E V V+L +V+ G+ +++ + DK+ ++++L+ ++ A + +G V
Sbjct: 176 AYTHAPIEGYYFESVCVILLFVMAGKRVEENSKDKALEAMQSLMRHQSLNALKIENGQSV 235
Query: 206 KVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMIN 265
+V E L+ GDI+ + PG +PVDGV+ +G + VD S L+GES+P KEG ++ +G +N
Sbjct: 236 EVPLESLQKGDILQILPGSYIPVDGVLFKGEAEVDESMLSGESLPVYKKEGMDLFAGTLN 295
Query: 266 LTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATV 325
T ++R T ++ST+++IL L+ A KA + + A + P V+GIA+ IA +
Sbjct: 296 TTTTFQMRATHTKAQSTLAKILTLIAKAQGSKAPIARLADKVAGVFVPIVIGIAS-IAFL 354
Query: 326 PPLVFKESFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALK 385
LV + FT + + ILVISCPCAL L+ P+ A+ G+ K + L+ K
Sbjct: 355 VWLVLGD-FTRALEVFIAILVISCPCALGLATPMALLVAQKEASLLGLFFKDAVSLEKAK 413
Query: 386 DASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKE 445
+ + V FDKTGTLT G V ++ G E+L A EA S H IAK I A+ KE
Sbjct: 414 NVNHVIFDKTGTLTLGTPLVQEVRVAEGVDRLELLTLCASLEAQSEHVIAKGI-VAHAKE 472
Query: 446 --INEAEITEYEEIAGHGVRARIDSVEVMVGNDKLLHRSNIEHDTCKVKGTIAHVVIDGQ 503
I E+ E + G G++ + + GN L N+ + ++G V + Q
Sbjct: 473 QGIALQEVQEVQAKPGFGIKGVVGDQIIKAGN---LEFFNLPNPFGTLEGIQVFVGTETQ 529
Query: 504 YAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPE 563
G +V++D +KE + A+ ELK LGV K +++GD+ + +A QLG+ ++A+ PE
Sbjct: 530 ILGVVVLADSLKEGSKEAISELKALGV-KTTLLSGDNLENVRALATQLGIQDYHAQAKPE 588
Query: 564 DKVKIIEKLEKEKGNGKLV-FVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDD 622
DK+K+I++L K GK+V VGDG+NDAP LA +DVGV M A GSDA++E ADVV ++
Sbjct: 589 DKLKVIQEL---KAQGKVVMMVGDGVNDAPSLALSDVGVVM-AKGSDASLEVADVVSFNN 644
Query: 623 KPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGLG---IFGKATMWEAVFADVGVALI 679
+ A++++ T + +N+ +A I L + M+ + A + ++L
Sbjct: 645 DIQSVVSAMKLSALTIANIKQNLFWAFCYNSIAIPLACGVAYKLGIMFNPMLASLAMSLS 704
Query: 680 A---VFNAMRV 687
+ V NA R+
Sbjct: 705 SVSVVLNAQRL 715
>gi|11434161 ATPase, Cu++ transporting, beta polypeptide (Wilson disease) [Homo
sapiens]
Length = 1163
Score = 290 bits (734), Expect = 4e-77
Identities = 237/813 (29%), Positives = 397/813 (48%), Gaps = 150/813 (18%)
Query: 5 KLKLEGLDCASCAYEIEEAL-RKEGFKFAVVNFATKEAIIEGDIE--KAKEVIKKVEPDV 61
+L + G+ CASC + IE L R G +A V AT +A+++ D E +++IK
Sbjct: 265 ELTITGMTCASCVHNIESKLTRTNGITYASVALATSKALVKFDPEIIGPRDIIK------ 318
Query: 62 EVVEEVHIH-------DHAHGEFEKRTI----------YFIGISLVLFTIGILM-----R 99
++EE+ H +AH K I GI ++ I +L+
Sbjct: 319 -IIEEIGFHASLAQRNPNAHHLDHKMEIKQWKKSFLCSLVFGIPVMALMIYMLIPSNEPH 377
Query: 100 YYYAIDNTLVFGLFLASY----------LISGWKVLKSAIVNSLNGNVFDENFLIAVATI 149
+D+ ++ GL + + L+ GW A SL + + LI +AT
Sbjct: 378 QSMVLDHNIIPGLSILNLIFFILCTFVQLLGGWYFYVQAY-KSLRHRSANMDVLIVLATS 436
Query: 150 GAFLIKEYPEGVAV------------------MLFYVIGEFLQDMAVDKSRRSIKALLAL 191
A++ VAV +F +G +L+ +A K+ ++ L++L
Sbjct: 437 IAYVYSLVILVVAVAEKAERSPVTFFDTPPMLFVFIALGRWLEHLAKSKTSEALAKLMSL 496
Query: 192 KAEYANLV---RDGTVVK---VKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALT 245
+A A +V D +++ V E ++ GDI+ V PG K PVDG ++EG + D S +T
Sbjct: 497 QATEATVVTLGEDNLIIREEQVPMELVQRGDIVKVVPGGKFPVDGKVLEGNTMADESLIT 556
Query: 246 GESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFIT 305
GE+MP T K G +++G IN G + ++ T +++T+++I++LVE A KA ++
Sbjct: 557 GEAMPVTKKPGSTVIAGSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKAPIQQLAD 616
Query: 306 RFAHYYTPAVVGIATLIATVPPLVFKESF----------------TSWVYR-----ALVI 344
RF+ Y+ P ++ ++TL V ++ F T + R ++ +
Sbjct: 617 RFSGYFVPFIIIMSTLTLVVWIVIGFIDFGVVQRYFPNPNKHISQTEVIIRFAFQTSITV 676
Query: 345 LVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFK 404
L I+CPC+L L+ P G G AA+ GILIKG L+ V FDKTGT+T GV +
Sbjct: 677 LCIACPCSLGLATPTAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKTGTITHGVPR 736
Query: 405 VTKIETRNGFTE---EEILRFAALAEAHSNHPIAKAIREAYGKEINEAEI---TEYEEIA 458
V ++ ++L AEA S HP+ A+ + +E+ + T+++ +
Sbjct: 737 VMRVLLLGDVATLPLRKVLAVVGTAEASSEHPLGVAVTKYCKEELGTETLGYCTDFQAVP 796
Query: 459 GHGVRARIDSVE-----------------------------------VMVGNDKLLHRSN 483
G G+ ++ +VE V++GN + L R+
Sbjct: 797 GCGIGCKVSNVEGILAHSERPLSAPASHLNEAGSLPAEKDAVPQTFSVLIGNREWLRRNG 856
Query: 484 --IEHDTC------KVKGTIAHVV-IDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVV 534
I D ++KG A +V IDG G I I+D +K++A LAV L+ +GV VV
Sbjct: 857 LTISSDVSDAMTDHEMKGQTAILVAIDGVLCGMIAIADAVKQEAALAVHTLQSMGV-DVV 915
Query: 535 MVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVL 594
++TGD+R A IA Q+G++ +AE+LP KV +++L+ KG K+ VGDG+ND+P L
Sbjct: 916 LITGDNRKTARAIATQVGINKVFAEVLPSHKVAKVQELQ-NKGK-KVAMVGDGVNDSPAL 973
Query: 595 ARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFAL----- 649
A+AD+GVA+G G+D AIE ADVV++ + + +I ++++T R + N++ AL
Sbjct: 974 AQADMGVAIGT-GTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIRINLVLALIYNLV 1032
Query: 650 GVKLA---FIGLGIFGKATMWEAVFADVGVALI 679
G+ +A F+ +GI + M A A V+++
Sbjct: 1033 GIPIAAGVFMPIGIVLQPWMGSAAMAASSVSVV 1065
>gb|AAB52902.1| (U03464) ATP7B [Homo sapiens]
Length = 1465
Score = 290 bits (734), Expect = 4e-77
Identities = 237/813 (29%), Positives = 397/813 (48%), Gaps = 150/813 (18%)
Query: 5 KLKLEGLDCASCAYEIEEAL-RKEGFKFAVVNFATKEAIIEGDIE--KAKEVIKKVEPDV 61
+L + G+ CASC + IE L R G +A V AT +A+++ D E +++IK
Sbjct: 567 ELTITGMTCASCVHNIESKLTRTNGITYASVALATSKALVKFDPEIIGPRDIIK------ 620
Query: 62 EVVEEVHIH-------DHAHGEFEKRTI----------YFIGISLVLFTIGILM-----R 99
++EE+ H +AH K I GI ++ I +L+
Sbjct: 621 -IIEEIGFHASLAQRNPNAHHLDHKMEIKQWKKSFLCSLVFGIPVMALMIYMLIPSNEPH 679
Query: 100 YYYAIDNTLVFGLFLASY----------LISGWKVLKSAIVNSLNGNVFDENFLIAVATI 149
+D+ ++ GL + + L+ GW A SL + + LI +AT
Sbjct: 680 QSMVLDHNIIPGLSILNLIFFILCTFVQLLGGWYFYVQAY-KSLRHRSANMDVLIVLATS 738
Query: 150 GAFLIKEYPEGVAV------------------MLFYVIGEFLQDMAVDKSRRSIKALLAL 191
A++ VAV +F +G +L+ +A K+ ++ L++L
Sbjct: 739 IAYVYSLVILVVAVAEKAERSPVTFFDTPPMLFVFIALGRWLEHLAKSKTSEALAKLMSL 798
Query: 192 KAEYANLV---RDGTVVK---VKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALT 245
+A A +V D +++ V E ++ GDI+ V PG K PVDG ++EG + D S +T
Sbjct: 799 QATEATVVTLGEDNLIIREEQVPMELVQRGDIVRVVPGGKFPVDGKVLEGNTMADESLIT 858
Query: 246 GESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFIT 305
GE+MP T K G +++G IN G + ++ T +++T+++I++LVE A KA ++
Sbjct: 859 GEAMPVTKKPGSTVIAGSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKAPIQQLAD 918
Query: 306 RFAHYYTPAVVGIATLIATVPPLVFKESF----------------TSWVYR-----ALVI 344
RF+ Y+ P ++ ++TL V ++ F T + R ++ +
Sbjct: 919 RFSGYFVPFIIIMSTLTLVVWIVIGFIDFGVVQKYFPNPNKHISQTEVIIRFAFQTSITV 978
Query: 345 LVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFK 404
L I+CPC+L L+ P G G AA+ GILIKG L+ V FDKTGT+T GV +
Sbjct: 979 LCIACPCSLGLATPTAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKTGTITHGVPR 1038
Query: 405 VTKIETRNGFTE---EEILRFAALAEAHSNHPIAKAIREAYGKEINEAEI---TEYEEIA 458
V ++ ++L AEA S HP+ A+ + +E+ + T+++ +
Sbjct: 1039 VMRVLLLGDVATLPLRKVLAVVGTAEASSEHPLGVAVTKYCKEELGTETLGYCTDFQAVP 1098
Query: 459 GHGVRARIDSVE-----------------------------------VMVGNDKLLHRSN 483
G G+ ++ +VE V++GN + L R+
Sbjct: 1099 GCGIGCKVSNVEGILAHSERPLSAPASHLNEAGSLPAEKDAAPQTFSVLIGNREWLRRNG 1158
Query: 484 --IEHDTC------KVKGTIAHVV-IDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVV 534
I D ++KG A +V IDG G I I+D +K++A LAV L+ +GV VV
Sbjct: 1159 LTISSDVSDAMTDHEMKGQTAILVAIDGVLCGMIAIADAVKQEAALAVHTLQSMGV-DVV 1217
Query: 535 MVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVL 594
++TGD+R A IA Q+G++ +AE+LP KV +++L+ KG K+ VGDG+ND+P L
Sbjct: 1218 LITGDNRKTARAIATQVGINKVFAEVLPSHKVAKVQELQ-NKGK-KVAMVGDGVNDSPAL 1275
Query: 595 ARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFAL----- 649
A+AD+GVA+G G+D AIE ADVV++ + + +I ++++T R + N++ AL
Sbjct: 1276 AQADMGVAIGT-GTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIRINLVLALIYNLV 1334
Query: 650 GVKLA---FIGLGIFGKATMWEAVFADVGVALI 679
G+ +A F+ +GI + M A A V+++
Sbjct: 1335 GIPIAAGVFMPIGIVLQPWMGSAAMAASSVSVV 1367
>pir||H82104 cation transport ATPase, E1-E2 family VC2215 [imported] - Vibrio
cholerae (group O1 strain N16961)
>gi|9656772|gb|AAF95359.1| (AE004293) cation transport
ATPase, E1-E2 family [Vibrio cholerae]
Length = 915
Score = 289 bits (732), Expect = 7e-77
Identities = 210/699 (30%), Positives = 359/699 (51%), Gaps = 56/699 (8%)
Query: 6 LKLEGLDCASCAYEIEEALRK-EGFKFAVVNFATKEAIIEGDIEKAKEVIKKVE------ 58
L ++G+ CASC +E+AL EG + A VN + A++ G + ++ ++
Sbjct: 176 LLIKGMTCASCVASVEKALLSVEGVQSAQVNLTEQSALVRGIFANPQPLLNAIQSSGYQA 235
Query: 59 -----PDVEVVEEVHIHDHAHGEFEKRTIYFIGISLVLFTIGIL---MRYYYAIDN---- 106
P + ++ + E ++ + I + L G+ M + D
Sbjct: 236 EILDDPAQQQAKQQAQLEALQKEHKQSALLGIALGTPLMLWGVFGGNMMIRNSSDQMVWG 295
Query: 107 ---TLVFGLFLAS---YLISGWKVLKS--AIVNSL----NGNVFDENFLIAV--ATIGAF 152
T+ F L L + + ++ W+ L A +++L G + + L+ T
Sbjct: 296 GIGTICFALLLTAGRHFFMNAWQALTHGRATMDTLVALGTGAAWFYSMLVVAWPQTFPDA 355
Query: 153 LIKEYPEGVAVMLFYV-IGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEE 211
Y E A+++ + +G +++ A + RS++ALL L+ + A LV + + +
Sbjct: 356 ARHVYFEATAMIIGLISLGHYIETKAKSNTNRSLQALLNLQPQQATLVTEQGDQSIAVAD 415
Query: 212 LKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLK 271
+++G + +KPGE+VPVDGV+ G S +D S LTGE +P + G ++ +G +N G L
Sbjct: 416 IQLGMSLRIKPGEQVPVDGVVSTGHSYLDESMLTGEPIPVLKEAGAKVAAGTLNQDGSLV 475
Query: 272 VRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFK 331
+ T +++ ++RI+++V A + K + + + + P VV IA L A + L
Sbjct: 476 ITATGIGAQTMLARIIQMVRQAQSSKPAMARLADQISSVFVPVVVVIAILSAALWYLYGP 535
Query: 332 ESFTSW-VYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIV 390
+ S+ + A +L+I+CPCAL L+ PL GIG+AA+ GILI+ +N L V
Sbjct: 536 DPKASYMLVVATTVLIIACPCALGLATPLSITVGIGKAAEMGILIRDANVLQTASQVDTV 595
Query: 391 AFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIRE-AYGKEINEA 449
FDKTGTLT G + + G E ++L A E S HP+AKAI + A + I+
Sbjct: 596 VFDKTGTLTLGKPSIQSLHVLQG-DENQLLALAYALEQQSEHPLAKAICDYAKQRNISPV 654
Query: 450 EITEYEEIAGHGVRARIDSVEVMVGN---------DKLLHRSNIEHDTCKVKGTIAHVVI 500
EI+++ G G+ A + V+VG+ D + S +E + +A V
Sbjct: 655 EISQFTNQRGRGLLADYQNQTVLVGSLAFMQEQGIDLSMAESTLEKFAAQAWTPVA-VAY 713
Query: 501 DGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAEL 560
G G + I+D IK + AV++L LG+ VM+TGD VA IAK+LG+ A++
Sbjct: 714 RGMLQGVLAIADPIKPTSAQAVRKLNELGIH-TVMLTGDHTSVANAIAKELGISQVIAQV 772
Query: 561 LPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIM 620
LP+ K + I+ L+++ K+ +GDGINDAP LA AD+G+AMG+ GSD AIE+A + ++
Sbjct: 773 LPDQKAQHIQALQQQ--GRKVAMIGDGINDAPALALADIGIAMGS-GSDVAIESAQMTLL 829
Query: 621 DDKPSKLPKAIQIARKTQRIVWENIIFA-----LGVKLA 654
+ P+ + AI++++ T R + +N+ A LG+ +A
Sbjct: 830 NSSPTSVVSAIELSKATLRNMKQNLFGAFIYNTLGIPIA 868
>sp|P96875|CTPC_MYCTU PROBABLE CATION-TRANSPORTING P-TYPE ATPASE C
>gi|7436392|pir||G70978 probable copper-transporting
atpase 11/9 - Mycobacterium tuberculosis (strain H37RV)
>gi|1877325|emb|CAB07083.1| (Z92771) ctpC [Mycobacterium
tuberculosis]
Length = 718
Score = 288 bits (729), Expect = 1e-76
Identities = 182/592 (30%), Positives = 321/592 (53%), Gaps = 33/592 (5%)
Query: 118 LISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEYPEGVAVMLFYVIGEFLQDMA 177
+ +G+ L+ A+ SL + L++ AT+ + +++E + V+ IGE+LQD+
Sbjct: 135 IFTGYPFLRGAL-RSLRSGKAGTDALVSAATVASLILRENVVALTVLWLLNIGEYLQDLT 193
Query: 178 VDKSRRSIKALLALKAEYANL-VRD-------GTVVKVKPEELKVGDIIIVKPGEKVPVD 229
+ ++RR+I LL + A + + D T ++V + +++GD ++V +PVD
Sbjct: 194 LRRTRRAISELLRGNQDTAWVRLTDPSAGSDAATEIQVPIDTVQIGDEVVVHEHVAIPVD 253
Query: 230 GVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILEL 289
G +++G + V+ SA+TGE++P +V G + +G + + G + VR +++T+ RI+
Sbjct: 254 GEVVDGEAIVNQSAITGENLPVSVVVGTRVHAGSVVVRGRVVVRAHAVGNQTTIGRIISR 313
Query: 290 VENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKESFTSWVYRALVILVISC 349
VE A +A + F+ + P + +++ + L+ T V RA+ +L+I+C
Sbjct: 314 VEEAQLDRAPIQTVGENFSRRFVPT----SFIVSAIALLI-----TGDVRRAMTMLLIAC 364
Query: 350 PCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIE 409
PCA+ LS P IG A+ GILIKG ++L+ + FDKTGTLT G VT I
Sbjct: 365 PCAVGLSTPTAISAAIGNGARRGILIKGGSHLEQAGRVDAIVFDKTGTLTVGRPVVTNIV 424
Query: 410 TRNGFTE-EEILRFAALAEAHSNHPIAKA-IREAYGKEINEAEITEYEEIAGHGVRARID 467
+ E E++L +AA +E HS HP+A+A IR + I+ E E + G G+R D
Sbjct: 425 AMHKDWEPEQVLAYAASSEIHSRHPLAEAVIRSTEERRISIPPHEECEVLVGLGMRTWAD 484
Query: 468 SVEVMVGNDKLLHRSNIE---------HDTCKVKGTIAHVVIDGQYAGYIVISDEIKEDA 518
+++G+ LL + + T + +DG G I + DE++ +A
Sbjct: 485 GRTLLLGSPSLLRAEKVRVSKKASEWVDKLRRQAETPLLLAVDGTLVGLISLRDEVRPEA 544
Query: 519 HLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGN 578
+ +L+ G+R++VM+TGD ++A+ +A +LG+D + AE++PEDK+ + +L+ +
Sbjct: 545 AQVLTKLRANGIRRIVMLTGDHPEIAQVVADELGIDEWRAEVMPEDKLAAVRELQDD--- 601
Query: 579 GKLV-FVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKT 637
G +V VGDGINDAP LA AD+G+AMG G+D A+ETADV + +D +L + +
Sbjct: 602 GYVVGMVGDGINDAPALAAADIGIAMGLAGTDVAVETADVALANDDLHRLLDVGDLGERA 661
Query: 638 QRIVWENIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIAVFNAMRVLR 689
++ +N ++ V A + +G G + A ++ V N+ R++R
Sbjct: 662 VDVIRQNYGMSIAVNAAGLLIGAGGALSPVLAAILHNASSVAVVANSSRLIR 713
>pir||T08988 cadmium-transporting ATPase homolog F6G3.150 - Arabidopsis thaliana
>gi|4938488|emb|CAB43847.1| (AL078464)
cadmium-transporting ATPase-like protein [Arabidopsis
thaliana]
Length = 689
Score = 288 bits (729), Expect = 1e-76
Identities = 180/613 (29%), Positives = 312/613 (50%), Gaps = 84/613 (13%)
Query: 84 FIGISLVLFTIGILMRYYYAIDNTLVFGLFLASYLISGWKVLKSAIVNSLNGNVFDENFL 143
F +S VL + +Y ++ L + + + + +L A+ S+ D N L
Sbjct: 96 FAIVSGVLLVLSFFKYFYSPLE-----WLAIVAVVAGVFPILAKAVA-SVTRFRLDINAL 149
Query: 144 IAVATIGAFLIKEYPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGT 203
+A I ++++ E ++ + + ++L+ A K+ + +L++L A + G
Sbjct: 150 TLIAVIATLCMQDFTEAATIVFLFSVADWLESSAAHKASIVMSSLMSLAPRKAVIADTGL 209
Query: 204 VVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGM 263
V V +E+ + ++ VK GE +P+DGV+++G+ VD LTGES P + + +++
Sbjct: 210 EVDV--DEVGINTVVSVKAGESIPIDGVVVDGSCDVDEKTLTGESFPVSKQRESTVMAAT 267
Query: 264 INLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIA 323
INL G +KV+ T + V+++ +LVE A + KT++FI + + YYTPAVV A A
Sbjct: 268 INLNGYIKVKTTALARDCVVAKMTKLVEEAQKSQTKTQRFIDKCSRYYTPAVVVSAACFA 327
Query: 324 TVPPLVFKESFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDA 383
+P L+ + + W + ALV+L AA G LIK + L+
Sbjct: 328 VIPVLLKVQDLSHWFHLALVVL----------------------AATSGFLIKTGDCLET 365
Query: 384 LKDASIVAFDKTGTLTKGVFKVTKIETRN-GFTEEEILRFAALAEAHSNHPIAKAIREAY 442
L IVAFDKTGT+TK F V+ + + ++L + + E S+HP+A A+ + Y
Sbjct: 366 LAKIKIVAFDKTGTITKAEFMVSDFRSLSPSINLHKLLYWVSSIECKSSHPMAAALID-Y 424
Query: 443 GKEIN---EAEITE-YEEIAGHGVRARIDSVEVMVGNDKLLHRSNIEHDTCKVKGTIAHV 498
+ ++ + +I E ++ G GV RID ++ +GN ++ R+ G + +
Sbjct: 425 ARSVSVEPKPDIVENFQNFPGEGVYGRIDGQDIYIGNKRIAQRA----------GCLTGI 474
Query: 499 VIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQL--GLDGF 556
+ M+TGD++D A +QL LD
Sbjct: 475 ---------------------------------QTAMLTGDNQDAAMSTQEQLENALDIV 501
Query: 557 YAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETAD 616
++ELLP+DK +II+ K G + VGDG+NDAP LA+AD+G++MG GS A ET D
Sbjct: 502 HSELLPQDKARIIDDF---KIQGPTMMVGDGLNDAPALAKADIGISMGISGSALATETGD 558
Query: 617 VVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGLGIFGKATMWEAVFADVGV 676
+++M + K+PK +++A+++ + V EN++ ++ +K A + LG G +W AV AD G
Sbjct: 559 IILMSNDIRKIPKGMRLAKRSHKKVIENVVLSVSIKGAIMVLGFVGYPLVWAAVLADAGT 618
Query: 677 ALIAVFNAMRVLR 689
L+ + N+M +LR
Sbjct: 619 CLLVILNSMMLLR 631
>pir||D72026 metal transport p-type ATPase - Chlamydophila pneumoniae (strain
CWL029) >gi|4377185|gb|AAD19006.1| (AE001667) Metal
Transport P-type ATPase [Chlamydophila pneumoniae
CWL029] >gi|8979242|dbj|BAA99076.1| (AP002548) metal
transport P-type ATPase [Chlamydophila pneumoniae J138]
Length = 658
Score = 287 bits (727), Expect = 3e-76
Identities = 201/618 (32%), Positives = 324/618 (51%), Gaps = 24/618 (3%)
Query: 87 ISLVLFTIGILMRYYYAIDNTLVFGLFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAV 146
+SL + I +L + +A + + +F +F ++ ++G L ++ N V + + L+
Sbjct: 49 LSLGTYLIALLSFWLHAKNLSNLFVVF--TFFLAGTPALIKSLDNICQ-KVVNIDILMTS 105
Query: 147 ATIGAFLIKEYPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLV-RDGTVV 205
A G+ I EG +++ + I E L M K++ ++ +L L LV DG +
Sbjct: 106 AAFGSIFIGGALEGALLLVLFAISEALGQMVSGKAKSTLVSLKQLAPTTGWLVLEDGNLQ 165
Query: 206 KVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMIN 265
KV +++VG+I+ +K GE VP+DG I+ G+SS++ LTGE +P++ G + +G N
Sbjct: 166 KVAINKIEVGNILRIKSGEVVPLDGEILHGSSSINLMHLTGEKVPKSCHPGSIVPAGAHN 225
Query: 266 LTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATV 325
+ G +RV R S+ST++ I+ LV A K + ++ + +++ Y ++ IA IA +
Sbjct: 226 MEGSFDLRVLRTGSDSTIAHIINLVIQAQNSKPRLQQRLDKYSSVYALSIFAIACGIALL 285
Query: 326 PPLVFKESFT---SWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLD 382
PL S YRAL L+ + PCAL+++IP+ Y I AK G+L+KG LD
Sbjct: 286 VPLFTSIPLLGPQSAFYRALAFLIAASPCALIIAIPIAYLSAINACAKHGVLLKGGVILD 345
Query: 383 ALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALA-EAHSNHPIAKAIRE- 440
L + V DKTGTLT G ++T I ++ E + LA E S+HPIA+AI
Sbjct: 346 RLVSCNSVVMDKTGTLTTG--ELTCIGCDYFGSKNETFFPSVLALEQSSSHPIAEAIVSY 403
Query: 441 AYGKEINEAEITEYEEIAGHGVRARIDSVEVMVGNDKL-------LHRSNIEHDTCKVK- 492
++++ Y + G GVR + E VG + + +IE + K
Sbjct: 404 LMEQKVSSLPADRYLTVPGEGVRGYFNEQEAFVGRVETGLGKVPSEYLEDIEQKIYQAKQ 463
Query: 493 -GTIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQL 551
G I + G D + A +++LK LG V M+TGD + AE A+ L
Sbjct: 464 HGEICSLAYVGNSFALFYFRDIPRPQAKEIIQDLKDLGY-PVSMLTGDHKVSAENTAEIL 522
Query: 552 GLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAA 611
G+ + +L PEDK+ I +L ++ +++ VGDGINDAP LA+A VG+AMG GS A
Sbjct: 523 GISEVFFDLTPEDKLAKIRELATQR---QIMMVGDGINDAPALAQATVGIAMGEAGSATA 579
Query: 612 IETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGLGIFGKATMWEAVF 671
IE AD+V++ D S LP IQ A++T+++V +N+ AL + L G +W AV
Sbjct: 580 IEAADIVLLHDSLSSLPWIIQKAKQTKKVVSQNLALALAIILLVSWPASLGIIPLWLAVI 639
Query: 672 ADVGVALIAVFNAMRVLR 689
G +I NA+R+L+
Sbjct: 640 LHEGSTVIVGLNALRLLK 657
>pir||C81515 cation-transporting ATPase, E1-E2 family CP1001 [imported] -
Chlamydophila pneumoniae (strain AR39)
>gi|7189914|gb|AAF38779.1| (AE002257)
cation-transporting ATPase, E1-E2 family [Chlamydophila
pneumoniae AR39]
Length = 683
Score = 287 bits (727), Expect = 3e-76
Identities = 201/618 (32%), Positives = 324/618 (51%), Gaps = 24/618 (3%)
Query: 87 ISLVLFTIGILMRYYYAIDNTLVFGLFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAV 146
+SL + I +L + +A + + +F +F ++ ++G L ++ N V + + L+
Sbjct: 74 LSLGTYLIALLSFWLHAKNLSNLFVVF--TFFLAGTPALIKSLDNICQ-KVVNIDILMTS 130
Query: 147 ATIGAFLIKEYPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLV-RDGTVV 205
A G+ I EG +++ + I E L M K++ ++ +L L LV DG +
Sbjct: 131 AAFGSIFIGGALEGALLLVLFAISEALGQMVSGKAKSTLVSLKQLAPTTGWLVLEDGNLQ 190
Query: 206 KVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMIN 265
KV +++VG+I+ +K GE VP+DG I+ G+SS++ LTGE +P++ G + +G N
Sbjct: 191 KVAINKIEVGNILRIKSGEVVPLDGEILHGSSSINLMHLTGEKVPKSCHPGSIVPAGAHN 250
Query: 266 LTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATV 325
+ G +RV R S+ST++ I+ LV A K + ++ + +++ Y ++ IA IA +
Sbjct: 251 MEGSFDLRVLRTGSDSTIAHIINLVIQAQNSKPRLQQRLDKYSSVYALSIFAIACGIALL 310
Query: 326 PPLVFKESFT---SWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLD 382
PL S YRAL L+ + PCAL+++IP+ Y I AK G+L+KG LD
Sbjct: 311 VPLFTSIPLLGPQSAFYRALAFLIAASPCALIIAIPIAYLSAINACAKHGVLLKGGVILD 370
Query: 383 ALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALA-EAHSNHPIAKAIRE- 440
L + V DKTGTLT G ++T I ++ E + LA E S+HPIA+AI
Sbjct: 371 RLVSCNSVVMDKTGTLTTG--ELTCIGCDYFGSKNETFFPSVLALEQSSSHPIAEAIVSY 428
Query: 441 AYGKEINEAEITEYEEIAGHGVRARIDSVEVMVGNDKL-------LHRSNIEHDTCKVK- 492
++++ Y + G GVR + E VG + + +IE + K
Sbjct: 429 LMEQKVSSLPADRYLTVPGEGVRGYFNEQEAFVGRVETGLGKVPSEYLEDIEQKIYQAKQ 488
Query: 493 -GTIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQL 551
G I + G D + A +++LK LG V M+TGD + AE A+ L
Sbjct: 489 HGEICSLAYVGNSFALFYFRDIPRPQAKEIIQDLKDLGY-PVSMLTGDHKVSAENTAEIL 547
Query: 552 GLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAA 611
G+ + +L PEDK+ I +L ++ +++ VGDGINDAP LA+A VG+AMG GS A
Sbjct: 548 GISEVFFDLTPEDKLAKIRELATQR---QIMMVGDGINDAPALAQATVGIAMGEAGSATA 604
Query: 612 IETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGLGIFGKATMWEAVF 671
IE AD+V++ D S LP IQ A++T+++V +N+ AL + L G +W AV
Sbjct: 605 IEAADIVLLHDSLSSLPWIIQKAKQTKKVVSQNLALALAIILLVSWPASLGIIPLWLAVI 664
Query: 672 ADVGVALIAVFNAMRVLR 689
G +I NA+R+L+
Sbjct: 665 LHEGSTVIVGLNALRLLK 682
>gi|4502323 ATPase, Cu++ transporting, beta polypeptide (Wilson disease); ATPase,
Cu++ transporting, beta polypeptide [Homo sapiens]
>gi|1703455|sp|P35670|AT7B_HUMAN COPPER-TRANSPORTING
ATPASE 2 (COPPER PUMP 2) (WILSON DISEASE-ASSOCIATED
PROTEIN) >gi|7428300|pir||S78555 copper-transporting
ATPase (EC 3.6.1.-) beta - human
>gi|551502|gb|AAA92667.1| (U11700) copper transporting
ATPase [Homo sapiens]
Length = 1465
Score = 287 bits (726), Expect = 3e-76
Identities = 236/813 (29%), Positives = 396/813 (48%), Gaps = 150/813 (18%)
Query: 5 KLKLEGLDCASCAYEIEEAL-RKEGFKFAVVNFATKEAIIEGDIE--KAKEVIKKVEPDV 61
+L + G+ CASC + IE L R G +A V AT +A+++ D E +++IK
Sbjct: 567 ELTITGMTCASCVHNIESKLTRTNGITYASVALATSKALVKFDPEIIGPRDIIK------ 620
Query: 62 EVVEEVHIH-------DHAHGEFEKRTI----------YFIGISLVLFTIGILM-----R 99
++EE+ H +AH K I GI ++ I +L+
Sbjct: 621 -IIEEIGFHASLAQRNPNAHHLDHKMEIKQWKKSFLCSLVFGIPVMALMIYMLIPSNEPH 679
Query: 100 YYYAIDNTLVFGLFLASY----------LISGWKVLKSAIVNSLNGNVFDENFLIAVATI 149
+D+ ++ GL + + L+ GW A SL + + LI +AT
Sbjct: 680 QSMVLDHNIIPGLSILNLIFFILCTFVQLLGGWYFYVQAY-KSLRHRSANMDVLIVLATS 738
Query: 150 GAFLIKEYPEGVAV------------------MLFYVIGEFLQDMAVDKSRRSIKALLAL 191
A++ VAV +F +G +L+ +A K+ ++ L++L
Sbjct: 739 IAYVYSLVILVVAVAEKAERSPVTFFDTPPMLFVFIALGRWLEHLAKSKTSEALAKLMSL 798
Query: 192 KAEYANLV---RDGTVVK---VKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALT 245
+A A +V D +++ V E ++ GDI+ V PG K PVDG ++EG + D S +T
Sbjct: 799 QATEATVVTLGEDNLIIREEQVPMELVQRGDIVKVVPGGKFPVDGKVLEGNTMADESLIT 858
Query: 246 GESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFIT 305
GE+MP T K G +++ IN G + ++ T +++T+++I++LVE A KA ++
Sbjct: 859 GEAMPVTKKPGSTVIARSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKAPIQQLAD 918
Query: 306 RFAHYYTPAVVGIATLIATVPPLVFKESF----------------TSWVYR-----ALVI 344
RF+ Y+ P ++ ++TL V ++ F T + R ++ +
Sbjct: 919 RFSGYFVPFIIIMSTLTLVVWIVIGFIDFGVVQKYFPNPNKHISQTEVIIRFAFQTSITV 978
Query: 345 LVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFK 404
L I+CPC+L L+ P G G AA+ GILIKG L+ V FDKTGT+T GV +
Sbjct: 979 LCIACPCSLGLATPTAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKTGTITHGVPR 1038
Query: 405 VTKIETRNGFTE---EEILRFAALAEAHSNHPIAKAIREAYGKEINEAEI---TEYEEIA 458
V ++ ++L AEA S HP+ A+ + +E+ + T+++ +
Sbjct: 1039 VMRVLLLGDVATLPLRKVLAVVGTAEASSEHPLGVAVTKYCKEELGTETLGYCTDFQAVP 1098
Query: 459 GHGVRARIDSVE-----------------------------------VMVGNDKLLHRSN 483
G G+ ++ +VE V++GN + L R+
Sbjct: 1099 GCGIGCKVSNVEGILAHSERPLSAPASHLNEAGSLPAEKDAVPQTFSVLIGNREWLRRNG 1158
Query: 484 --IEHDTC------KVKGTIAHVV-IDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVV 534
I D ++KG A +V IDG G I I+D +K++A LAV L+ +GV VV
Sbjct: 1159 LTISSDVSDAMTDHEMKGQTAILVAIDGVLCGMIAIADAVKQEAALAVHTLQSMGV-DVV 1217
Query: 535 MVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVL 594
++TGD+R A IA Q+G++ +AE+LP KV +++L+ KG K+ VGDG+ND+P L
Sbjct: 1218 LITGDNRKTARAIATQVGINKVFAEVLPSHKVAKVQELQ-NKGK-KVAMVGDGVNDSPAL 1275
Query: 595 ARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFAL----- 649
A+AD+GVA+G G+D AIE ADVV++ + + +I ++++T R + N++ AL
Sbjct: 1276 AQADMGVAIGT-GTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIRINLVLALIYNLV 1334
Query: 650 GVKLA---FIGLGIFGKATMWEAVFADVGVALI 679
G+ +A F+ +GI + M A A V+++
Sbjct: 1335 GIPIAAGVFMPIGIVLQPWMGSAAMAASSVSVV 1367
>gb|AAB94620.1| (AF032881) ATP7B [Ovis aries]
Length = 1444
Score = 286 bits (725), Expect = 4e-76
Identities = 225/812 (27%), Positives = 392/812 (47%), Gaps = 149/812 (18%)
Query: 5 KLKLEGLDCASCAYEIEEALRK-EGFKFAVVNFATKEAIIEGDIE--KAKEVIKKVEPD- 60
+L + G+ CASC + IE LR+ EG +A V AT +A ++ D E ++++K +E
Sbjct: 547 ELMITGMTCASCVHNIESKLRRTEGITYASVALATSKAHVKFDPEIIGPRDIVKLIEEIG 606
Query: 61 -----VEVVEEVHIHDHAHGEFEKRTIYFIGISLVLFTIGILMRYYY--------AIDNT 107
+ + H DH + + + + + +G+++ +D+
Sbjct: 607 FRASLAQRIPNAHHLDHKVEIKQWKNSFLCSLVFGIPVMGLMIYMLIPSHEPQSSVLDHN 666
Query: 108 LVFGLFLASYL----------ISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEY 157
++ GL + + + + GW A SL + + + LI +AT A++
Sbjct: 667 VIPGLSILNLIFFILCTFVQFLGGWYFYVQAY-KSLRHGMANMDVLIVLATSIAYVYSLV 725
Query: 158 PEGVAV------------------MLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLV 199
VAV +F +G +L+ + K+ ++ L++L+A A +V
Sbjct: 726 ILVVAVAEKAERSPVTFFDTPPMLFVFIALGRWLEHVVKSKTSEALARLMSLQATEATVV 785
Query: 200 ---RDGTVVK---VKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTV 253
D +++ V E ++ GDII V PG K PVDG ++EG + D S +TGE+MP T
Sbjct: 786 TLGEDNVIIREEQVPMELVQRGDIIKVVPGGKFPVDGKVLEGNTMADESLITGEAMPVTK 845
Query: 254 KEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTP 313
K G +++G +N G + + T +++T+++I++LVE A KA ++ RF+ Y+ P
Sbjct: 846 KPGSMVIAGSMNAHGSVLITATHVGNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGYFVP 905
Query: 314 AVVGIATLIATV-------------------------PPLVFKESFTSWVYRALVILVIS 348
++ I+T+ V +V + +F + ++ +L I+
Sbjct: 906 FIIIISTVTLVVWIVIGFIDFGVVQKYFPAPSKGISQAEVVLRFAFQT----SITVLCIA 961
Query: 349 CPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKI 408
CPC+L L+ P G G AA+ GILIKG L+ V FDKTGT+T GV KV+++
Sbjct: 962 CPCSLGLATPTAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKTGTITHGVPKVSRV 1021
Query: 409 ETRNGFTE---EEILRFAALAEAHSNHPIAKAIREAYGKEINEAEI---TEYEEIAGHGV 462
++L AEA S HP+ A+ +E+ + +++ + G G+
Sbjct: 1022 LLLVDLATLPLRKVLAVVGTAEASSEHPLGVAVTRYCKEELGTETLGCCMDFQAVPGCGI 1081
Query: 463 RARIDSVE-----------------------------------VMVGNDKLLHRSNI--- 484
++ SVE V++GN + + R+ +
Sbjct: 1082 SCKVSSVESILAQGERLQGPPTAHQNRVGSEPSETDAATQTFSVLIGNREWMRRNGLTVT 1141
Query: 485 --------EHDTCKVKG-TIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVM 535
+H+T KG T V IDG G I ++D +K++A LAV LK +GV VV+
Sbjct: 1142 SDVRDAMTDHET---KGQTAILVAIDGVLCGMIAVADSVKQEAALAVHTLKSMGV-DVVL 1197
Query: 536 VTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLA 595
+TGD+R A IA Q+G++ +AE+LP KV +++L+ + ++ VGDG+ND+P LA
Sbjct: 1198 ITGDNRKTARAIATQVGINKVFAEVLPSHKVAKVQELQNQ--GKRVAMVGDGVNDSPALA 1255
Query: 596 RADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFAL-----G 650
+ADVG+A+G G+D AIE ADVV++ + + +I ++R+T + N++ AL G
Sbjct: 1256 QADVGIAIGT-GTDVAIEAADVVLIRNDLLDVVASIHLSRRTVWRIRLNLVLALIYNLIG 1314
Query: 651 VKLA---FIGLGIFGKATMWEAVFADVGVALI 679
+ +A FI +G+ + M A A V+++
Sbjct: 1315 IPVAAGVFIPIGVVLQPWMGSAAMAASSVSVV 1346
>gb|AAD39371.1|AF118225_1 (AF118225) ATP7B protein [Ovis aries]
Length = 1505
Score = 286 bits (725), Expect = 4e-76
Identities = 225/812 (27%), Positives = 392/812 (47%), Gaps = 149/812 (18%)
Query: 5 KLKLEGLDCASCAYEIEEALRK-EGFKFAVVNFATKEAIIEGDIE--KAKEVIKKVEPD- 60
+L + G+ CASC + IE LR+ EG +A V AT +A ++ D E ++++K +E
Sbjct: 608 ELMITGMTCASCVHNIESKLRRTEGITYASVALATSKAHVKFDPEIIGPRDIVKLIEEIG 667
Query: 61 -----VEVVEEVHIHDHAHGEFEKRTIYFIGISLVLFTIGILMRYYY--------AIDNT 107
+ + H DH + + + + + +G+++ +D+
Sbjct: 668 FRASLAQRIPNAHHLDHKVEIKQWKNSFLCSLVFGIPVMGLMIYMLIPSHEPQSSVLDHN 727
Query: 108 LVFGLFLASYL----------ISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEY 157
++ GL + + + + GW A SL + + + LI +AT A++
Sbjct: 728 VIPGLSILNLIFFILCTFVQFLGGWYFYVQAY-KSLRHGMANMDVLIVLATSIAYVYSLV 786
Query: 158 PEGVAV------------------MLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLV 199
VAV +F +G +L+ + K+ ++ L++L+A A +V
Sbjct: 787 ILVVAVAEKAERSPVTFFDTPPMLFVFIALGRWLEHVVKSKTSEALARLMSLQATEATVV 846
Query: 200 ---RDGTVVK---VKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTV 253
D +++ V E ++ GDII V PG K PVDG ++EG + D S +TGE+MP T
Sbjct: 847 TLGEDNVIIREEQVPMELVQRGDIIKVVPGGKFPVDGKVLEGNTMADESLITGEAMPVTK 906
Query: 254 KEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTP 313
K G +++G +N G + + T +++T+++I++LVE A KA ++ RF+ Y+ P
Sbjct: 907 KPGSMVIAGSMNAHGSVLITATHVGNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGYFVP 966
Query: 314 AVVGIATLIATV-------------------------PPLVFKESFTSWVYRALVILVIS 348
++ I+T+ V +V + +F + ++ +L I+
Sbjct: 967 FIIIISTVTLVVWIVIGFIDFGVVQKYFPAPSKGISQAEVVLRFAFQT----SITVLCIA 1022
Query: 349 CPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKI 408
CPC+L L+ P G G AA+ GILIKG L+ V FDKTGT+T GV KV+++
Sbjct: 1023 CPCSLGLATPTAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKTGTITHGVPKVSRV 1082
Query: 409 ETRNGFTE---EEILRFAALAEAHSNHPIAKAIREAYGKEINEAEI---TEYEEIAGHGV 462
++L AEA S HP+ A+ +E+ + +++ + G G+
Sbjct: 1083 LLLVDLATLPLRKVLAVVGTAEASSEHPLGVAVTRYCKEELGTETLGCCMDFQAVPGCGI 1142
Query: 463 RARIDSVE-----------------------------------VMVGNDKLLHRSNI--- 484
++ SVE V++GN + + R+ +
Sbjct: 1143 SCKVSSVESILAQGERLQGPPTAHQNRVGSEPSETDAATQTFSVLIGNREWMRRNGLTVT 1202
Query: 485 --------EHDTCKVKG-TIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVM 535
+H+T KG T V IDG G I ++D +K++A LAV LK +GV VV+
Sbjct: 1203 SDVRDAMTDHET---KGQTAILVAIDGVLCGMIAVADSVKQEAALAVHTLKSMGV-DVVL 1258
Query: 536 VTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLA 595
+TGD+R A IA Q+G++ +AE+LP KV +++L+ + ++ VGDG+ND+P LA
Sbjct: 1259 ITGDNRKTARAIATQVGINKVFAEVLPSHKVAKVQELQNQ--GKRVAMVGDGVNDSPALA 1316
Query: 596 RADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFAL-----G 650
+ADVG+A+G G+D AIE ADVV++ + + +I ++R+T + N++ AL G
Sbjct: 1317 QADVGIAIGT-GTDVAIEAADVVLIRNDLLDVVASIHLSRRTVWRIRLNLVLALIYNLIG 1375
Query: 651 VKLA---FIGLGIFGKATMWEAVFADVGVALI 679
+ +A FI +G+ + M A A V+++
Sbjct: 1376 IPVAAGVFIPIGVVLQPWMGSAAMAASSVSVV 1407
>dbj|BAA84775.1| (AB017791) ATPase 7B [Rattus norvegicus] >gi|6006304|dbj|BAA84776.1|
(AB017792) ATPase 7B [Rattus norvegicus]
>gi|6006306|dbj|BAA84777.1| (AB017793) ATPase 7B [Rattus
norvegicus]
Length = 1452
Score = 286 bits (723), Expect = 8e-76
Identities = 233/801 (29%), Positives = 393/801 (48%), Gaps = 131/801 (16%)
Query: 5 KLKLEGLDCASCAYEIEEAL-RKEGFKFAVVNFATKEAIIEGDIE--KAKEVIKKVEPDV 61
+L + G+ CASC + IE L R G +A V AT +A ++ D E +++IK +E
Sbjct: 559 ELIITGMTCASCVHNIESKLTRTNGITYASVALATSKAHVKFDPEIIGPRDIIKVIEEIG 618
Query: 62 EVVEEVHIHDHAHGEFEKRTI----------YFIGISLVLFTIGILM-----RYYYAIDN 106
H + +AH K I GI ++ I +L+ +D+
Sbjct: 619 FHASLAHRNPNAHHLDHKTEIKQWKKSFLCSLVFGIPVMGLMIYMLIPSSKPHETMVLDH 678
Query: 107 TLVFGLFLASYL----------ISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFL--- 153
++ GL + + + + GW A SL + + LI +AT A+
Sbjct: 679 NIIPGLSVLNLIFFILCTFVQFLGGWYFYVQAY-KSLRHKSANMDVLIVLATTIAYAYSL 737
Query: 154 ------IKEYPEGVAV---------MLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANL 198
I E E V +F +G +L+ +A K+ ++ L++L+A A +
Sbjct: 738 VILVVAIAEKAEKSPVTFFDTPPMLFVFIALGRWLEHVAKSKTSEALAKLMSLQATEATV 797
Query: 199 V---RDGTVVK---VKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRT 252
V D +++ V E ++ GDII V PG K PVDG ++EG + D S +TGE+MP T
Sbjct: 798 VTLGEDNLILREEQVPMELVQRGDIIKVVPGGKFPVDGKVLEGNTMADESLITGEAMPVT 857
Query: 253 VKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYT 312
K G +++G IN G + ++ T +++T+++I++LVE A KA ++ RF+ Y+
Sbjct: 858 KKPGSIVIAGSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGYFV 917
Query: 313 PAVVGIATLIATVPPLVFKESF----------------TSWVYR-----ALVILVISCPC 351
P ++ I+TL V ++ F T + R ++ +L I+CPC
Sbjct: 918 PFIIIISTLTLVVWIIIGFVDFGIVQKYFPSPSKHISQTEVIIRFAFQTSITVLCIACPC 977
Query: 352 ALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTK---I 408
+L L+ P G G AA+ G+LIKG L+ V FDKTGT+T GV +V + +
Sbjct: 978 SLGLATPTAVMVGTGVAAQNGVLIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRFLLL 1037
Query: 409 ETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKEINEAEI---TEYEEIAGHGVRAR 465
+ ++L AEA S HP+ A+ + +E+ + T+++ + G G+ +
Sbjct: 1038 VDVATLSLRKVLAVVGTAEASSEHPLGVAVTKYCKEELGTETLGYSTDFQAVPGCGISCK 1097
Query: 466 IDSVE------------------------------VMVGNDKLLHRSNIEHDTC------ 489
+ +VE V++GN + + R+ + +
Sbjct: 1098 VSNVESILAHRGPTAHPIGVGNPPIGEGTGPQTFSVLIGNREWMRRNGLTISSDISDAMT 1157
Query: 490 --KVKGTIAHVV-IDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEE 546
++KG A +V IDG G I I+D +K +A LA+ LK +GV V ++TGD+R A
Sbjct: 1158 DHEMKGQTAILVAIDGVLCGMIAIADAVKPEAALAIYTLKSMGV-DVALITGDNRKTARA 1216
Query: 547 IAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGAL 606
IA Q+G++ +AE+LP KV +++L+ KG K+ VGDG+ND+P LA+ADVG+A+G
Sbjct: 1217 IATQVGINKVFAEVLPSHKVAKVQELQN-KGK-KVAMVGDGVNDSPALAQADVGIAIGT- 1273
Query: 607 GSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFAL-----GVKLA---FIGL 658
G+D AIE ADVV++ + + +I ++++T R + N++ AL G+ +A F+ +
Sbjct: 1274 GTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIRVNLVLALIYNMVGIPIAAGVFMPI 1333
Query: 659 GIFGKATMWEAVFADVGVALI 679
GI + M A A V+++
Sbjct: 1334 GIVLQPWMGSAAMAASSVSVV 1354
>sp|P73241|ATCS_SYNY3 CATION-TRANSPORTING ATPASE PACS >gi|7428303|pir||S75354 probable
copper-transporting ATPase (EC 3.6.1.-) sll1920 -
Synechocystis sp. (strain PCC 6803)
>gi|1652345|dbj|BAA17268.1| (D90904) cation-transporting
ATPase [Synechocystis sp.]
Length = 745
Score = 285 bits (721), Expect = 1e-75
Identities = 207/699 (29%), Positives = 362/699 (51%), Gaps = 67/699 (9%)
Query: 6 LKLEGLDCASCAYEIEEALRK-EGFKFAVVNFATKEAIIEGDIEKAKEVIKKVEPDVEVV 64
L+LEG+ CA+CA IE A+ K G + VNFA ++A++ E +++ + V
Sbjct: 7 LQLEGMRCAACASSIERAIAKVPGVQSCQVNFALEQAVVSYHGETTPQIL------TDAV 60
Query: 65 EEVHIHDHAHGE--------------FEKRTIYFIGISLVLF------TIGILMRYYYAI 104
E H + F + + + IS VLF +G+ + ++ I
Sbjct: 61 ERAGYHARVLKQQVLSSQQTEDRKPVFSAKLVTGLVISAVLFFGSLPMMLGVNIPHFPHI 120
Query: 105 DNTLVFGLFLAS---------YLISGWKVLK--SAIVNSLN--GNVFDENFLIAVATIGA 151
+ LA+ + WK ++ SA +++L G + +A+
Sbjct: 121 FHDPWLQWLLATPVQFWSGAEFYRGAWKSVRTRSATMDTLVALGTSAAYFYSVAITLFPQ 180
Query: 152 FLIKE------YPEGVAVMLFYVI-GEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTV 204
+L + Y E AV++ ++ G L+ A ++ +I+ L+ L+ + A + R
Sbjct: 181 WLTSQGLAAHVYFEAAAVVITLILLGRSLEQRARRETSAAIRKLMGLQPQTALVKRGEHW 240
Query: 205 VKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMI 264
V EL + D++ V+PGEK+PVDGV++ G S+VD S +TGES P G E++ +
Sbjct: 241 ETVAIAELAINDVVRVRPGEKIPVDGVVVAGNSTVDESLVTGESFPVDKTVGTEVIGATL 300
Query: 265 NLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIAT 324
N +G L ++V++ +S +++I++LV+ A A KA + F+ R H++ P V+ +A
Sbjct: 301 NKSGSLDIQVSKLGQDSVLAQIIQLVQQAQASKAPIQHFVDRITHWFVPTVIVVAIAAFC 360
Query: 325 VPPLVFKESFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDAL 384
+ L + T V + +L+I+CPCAL L+ P G G+ A+ G+LIK ++ L+
Sbjct: 361 IWWLT-TGNITLAVLTLVEVLIIACPCALGLATPTSVMVGTGKGAEYGVLIKEASSLEMA 419
Query: 385 KDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEE---ILRFAALAEAHSNHPIAKA-IRE 440
+ + + DKTGTLT+G VT T + + EE ++++AA E +S HP+A+A +
Sbjct: 420 EKLTAIVLDKTGTLTQGKPSVTNFFTLSPTSTEESLQLIQWAASVEQYSEHPLAEAVVNY 479
Query: 441 AYGKEINEAEITEYEEIAGHGVRARIDSVEVMVGNDKLLHRSNI---EHDTC-------- 489
++++ EI ++ IAG GV + + +G L + EH
Sbjct: 480 GQSQQVSLLEIDNFQAIAGCGVAGQWQGQWIRLGTSNWLTDLGVTGTEHQPWQSQAQQWE 539
Query: 490 KVKGTIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAK 549
K + T+ + +D + + I+D IK + V+ LK+LG+ V M+TGD++ A+ IA
Sbjct: 540 KEQKTVIWLAVDTEVKALLAIADAIKPSSPQVVQALKKLGL-SVYMLTGDNQATAQAIAD 598
Query: 550 QLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSD 609
+G+ A++ P DK + +E+L+ +KGN + VGDGINDAP LA+ADVG+A+G G+D
Sbjct: 599 TVGIRHVLAQVRPGDKAQQVEQLQ-QKGN-IVAMVGDGINDAPALAQADVGIAIGT-GTD 655
Query: 610 AAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFA 648
AI +D+ ++ + AI+++R T + +N+ FA
Sbjct: 656 VAIAASDITLIAGDLQGILTAIKLSRATMGNIRQNLFFA 694
>gb|AAC15948.1| (U82820) metal transporting ATPase Mta72 [Mycobacterium
tuberculosis]
Length = 680
Score = 284 bits (719), Expect = 2e-75
Identities = 177/567 (31%), Positives = 310/567 (54%), Gaps = 32/567 (5%)
Query: 143 LIAVATIGAFLIKEYPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANL-VRD 201
L++ AT+ + +++E + V+ IGE+LQD+ + ++RR+I LL + A + + D
Sbjct: 121 LVSAATVASLILRENVVALTVLWLLNIGEYLQDLTLRRTRRAISELLRGNQDTAWVRLTD 180
Query: 202 -------GTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVK 254
T ++V + +++GD ++V +PVDG +++G + V+ SA+TGE++P +V
Sbjct: 181 PSAGSDAATEIQVPIDTVQIGDEVVVHEHVAIPVDGEVVDGEAIVNQSAITGENLPVSVV 240
Query: 255 EGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPA 314
G + +G + + G + VR +++T+ RI+ VE A +A + F+ + P
Sbjct: 241 VGTRVHAGSVVVRGRVVVRAHAVGNQTTIGRIISRVEEAQLDRAPIQTVGENFSRRFVPT 300
Query: 315 VVGIATLIATVPPLVFKESFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGIL 374
+ +++ + L+ T V RA+ +L+I+CPCA+ LS P IG A+ GIL
Sbjct: 301 ----SFIVSAIALLI-----TGDVRRAMTMLLIACPCAVGLSTPTAISAAIGNGARRGIL 351
Query: 375 IKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTE-EEILRFAALAEAHSNHP 433
IKG ++L+ + FDKTGTLT G VT I + E E++L +AA +E HS HP
Sbjct: 352 IKGGSHLEQAGRVDAIVFDKTGTLTVGRPVVTNIVAMHKDWEPEQVLAYAASSEIHSRHP 411
Query: 434 IAKA-IREAYGKEINEAEITEYEEIAGHGVRARIDSVEVMVGNDKLLHRSNIE------- 485
+A+A IR + I+ E E + G G+R D +++G+ LL +
Sbjct: 412 LAEAVIRSTEERRISIPPHEECEVLVGLGMRTWADGRTLLLGSPSLLRAEKVRVSKKASE 471
Query: 486 --HDTCKVKGTIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDV 543
+ T + +DG G I + DE++ +A + +L+ G+R++VM+TGD ++
Sbjct: 472 WVDKLRRQAETPLLLAVDGTLVGLISLRDEVRPEAAQVLTKLRANGIRRIVMLTGDHPEI 531
Query: 544 AEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLV-FVGDGINDAPVLARADVGVA 602
A+ +A +LG+D + AE++PEDK+ + +L+ + G +V VGDGINDAP LA AD+G+A
Sbjct: 532 AQVVADELGIDEWRAEVMPEDKLAAVRELQDD---GYVVGMVGDGINDAPALAAADIGIA 588
Query: 603 MGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGLGIFG 662
MG G+D A+ETADV + +D +L + + ++ +N ++ V A + +G G
Sbjct: 589 MGLAGTDVAVETADVALANDDLHRLLDVGDLGERAVDVIRQNYGMSIAVNAAGLLIGAGG 648
Query: 663 KATMWEAVFADVGVALIAVFNAMRVLR 689
+ A ++ V N+ R++R
Sbjct: 649 ALSPVLAAILHNASSVAVVANSSRLIR 675
>sp|Q59385|ATCU_ECOLI PROBABLE COPPER-TRANSPORTING ATPASE >gi|7428302|pir||C64779
probable copper-transporting ATPase (EC 3.6.1.-) -
Escherichia coli >gi|1773166|gb|AAB40238.1| (U82664)
probable copper-transporting atpase [Escherichia coli]
>gi|1786691|gb|AAC73586.1| (AE000154) putative ATPase
[Escherichia coli K12]
Length = 834
Score = 284 bits (718), Expect = 3e-75
Identities = 221/742 (29%), Positives = 370/742 (49%), Gaps = 69/742 (9%)
Query: 4 RKLKLEGLDCASCAYEIEEALRK-EGFKFAVVNFATKEAIIEGDI--EKAKEVIKKVEPD 60
++L L G+ CASC ++ AL+ G A VN A + A++ G + + ++K
Sbjct: 101 QQLLLSGMSCASCVTRVQNALQSVPGVTQARVNLAERTALVMGSASPQDLVQAVEKAGYG 160
Query: 61 VEVVEEVHIHDHAHGEFEKRTIY-FIGISLVLFTIGILMRYYYAIDNT-----------L 108
E +E+ E T+ F ++V +GI + + I + L
Sbjct: 161 AEAIEDDAKRRERQQETAVATMKRFRWQAIVALAVGIPVMVWGMIGDNMMVTADNRSLWL 220
Query: 109 VFGLF-LASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKE----------- 156
V GL LA + +G +SA + LNG + L+A+ T A+L
Sbjct: 221 VIGLITLAVMVFAGGHFYRSAWKSLLNGAATMDT-LVALGTGVAWLYSMSVNLWPQWFPM 279
Query: 157 -----YPEGVAVMLFYV-IGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPE 210
Y E A+++ + +G L+ A +S ++++ LL L A LV D V
Sbjct: 280 EARHLYYEASAMIIGLINLGHMLEARARQRSSKALEKLLDLTPPTARLVTDEGEKSVPLA 339
Query: 211 ELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLL 270
E++ G ++ + G++VPVDG I +G + +D + LTGE +P+ EGD + +G + G +
Sbjct: 340 EVQPGMLLRLTTGDRVPVDGEITQGEAWLDEAMLTGEPIPQQKGEGDSVHAGTVVQDGSV 399
Query: 271 KVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATV----- 325
R + S +T+SRI+ +V A + K + + + + + P VV IA + A +
Sbjct: 400 LFRASAVGSHTTLSRIIRMVRQAQSSKPEIGQLADKISAVFVPVVVVIALVSAAIWYFFG 459
Query: 326 --PPLVFKESFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDA 383
P +V+ + A +L+I+CPCAL L+ P+ G+GRAA+ G+L++ ++ L
Sbjct: 460 PAPQIVYT------LVIATTVLIIACPCALGLATPMSIISGVGRAAEFGVLVRDADALQR 513
Query: 384 LKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYG 443
V FDKTGTLT+G +V ++T E + LR AA E S+HP+A+AI + G
Sbjct: 514 ASTLDTVVFDKTGTLTEGKPQVVAVKTFADVDEAQALRLAAALEQGSSHPLARAILDKAG 573
Query: 444 KEINEAEITEYEEIAGHGVRARIDSVEVMVGNDKLLHRSNIEHDTCKVK--------GTI 495
++ ++ + + G GV + +++GN LL+ + + + T
Sbjct: 574 -DMQLPQVNGFRTLRGLGVSGEAEGHALLLGNQALLNEQQVGTKAIEAEITAQASQGATP 632
Query: 496 AHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDG 555
+ +DG+ + + D ++ D+ A++ L + G R +VM+TGD+ A IAK+ G+D
Sbjct: 633 VLLAVDGKAVALLAVRDPLRSDSVAALQRLHKAGYR-LVMLTGDNPTTANAIAKEAGIDE 691
Query: 556 FYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETA 615
A +LP+ K + I+ L+ E ++ VGDGINDAP LA+ADVG+AMG GSD AIETA
Sbjct: 692 VIAGVLPDGKAEAIKHLQSE--GRQVAMVGDGINDAPALAQADVGIAMGG-GSDVAIETA 748
Query: 616 DVVIMDDKPSKLPKAIQIARKTQRIVWENIIFA-----LGVKLAFIGLGIFGKATMWEAV 670
+ +M + A+ I+R T + +N++ A +G+ +A L F T+ V
Sbjct: 749 AITLMRHSLMGVADALAISRATLHNMKQNLLGAFIYNSIGIPVAAGILWPF-TGTLLNPV 807
Query: 671 FADVGVAL---IAVFNAMRVLR 689
A +AL V NA R+LR
Sbjct: 808 VAGAAMALSSITVVSNANRLLR 829
>gi|6978561 ATPase, Cu++ transporting, beta polypeptide (same as Wilson disease)
[Rattus norvegicus] >gi|3121725|sp|Q64535|AT7B_RAT
COPPER-TRANSPORTING ATPASE 2 (COPPER PUMP 2)
>gi|2143667|pir||I58124 copper-transporting ATPase (EC
3.6.1.-) beta chain - rat >gi|555676|gb|AAA62157.1|
(U08344) copper-transporting ATPase [Rattus norvegicus]
Length = 1451
Score = 283 bits (716), Expect = 5e-75
Identities = 233/800 (29%), Positives = 391/800 (48%), Gaps = 131/800 (16%)
Query: 5 KLKLEGLDCASCAYEIEEAL-RKEGFKFAVVNFATKEAIIEGDIE--KAKEVIKKVEPDV 61
+L + G+ CASC + IE L R G +A V AT +A ++ D E +++IK +E
Sbjct: 560 ELIITGMTCASCVHNIESKLTRTNGITYASVALATSKAHVKFDPEIIGPRDIIKVIEEIG 619
Query: 62 EVVEEVHIHDHAHGEFEKRTI----------YFIGISLVLFTIGILM-----RYYYAIDN 106
H + +AH K I GI ++ I +L+ +D+
Sbjct: 620 FHASLAHRNPNAHHLDHKTEIKQWKKSFLCSLVFGIPVMGLMIYMLIPSSKPHETMVLDH 679
Query: 107 TLVFGLFLASYL----------ISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFL--- 153
++ GL + + + + GW A SL + + LI +AT A+
Sbjct: 680 NIIPGLSVLNLIFFILCTFVQFLGGWYFYVQAY-KSLRHKSANMDVLIVLATTIAYAYSL 738
Query: 154 ------IKEYPEGVAV---------MLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANL 198
I E E V +F +G +L+ +A K+ ++ L++L+A A +
Sbjct: 739 VILVVAIAEKAEKSPVTFFDTPPMLFVFIALGRWLEHVAKSKTSEALAKLMSLQATEATV 798
Query: 199 V---RDGTVVK---VKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRT 252
V D +++ V E ++ GDII V PG K PVDG ++EG + D S +TGE+MP T
Sbjct: 799 VTLGEDNLILREEQVPMELVQRGDIIKVVPGGKFPVDGKVLEGNTMADESLITGEAMPVT 858
Query: 253 VKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYT 312
K G +++G IN G + ++ T +++T+++I++LVE A KA ++ RF+ Y+
Sbjct: 859 KKPGSIVIAGSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGYFV 918
Query: 313 PAVVGIATLIATVPPLVFKESF----------------TSWVYR-----ALVILVISCPC 351
P ++ I+TL V ++ F T + R ++ +L I+CPC
Sbjct: 919 PFIIIISTLTLVVWIIIGFVDFGIVQKYFPSPSKHISQTEVIIRFAFQTSITVLCIACPC 978
Query: 352 ALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTK---I 408
+L L+ P G G AA+ G+LIKG L+ V FDKTGT+T GV +V + +
Sbjct: 979 SLGLATPTAVMVGTGVAAQNGVLIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRFLLL 1038
Query: 409 ETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKEINEAEI---TEYEEIAGHGVRAR 465
+ ++L AEA S HP+ A+ + +E+ + T+++ + G G+ +
Sbjct: 1039 VDVATLSLRKVLAVVGTAEASSEHPLGVAVTKYCKEELGTETLGYSTDFQAVPGCGISCK 1098
Query: 466 IDSVE------------------------------VMVGNDKLLHRSNIEHDTC------ 489
+ +VE V++GN + + R+ + +
Sbjct: 1099 VSNVESILAHRGPTAHPIGVGNPPIGEGTGPQTFSVLIGNREWMRRNGLTISSDISDAMT 1158
Query: 490 --KVKGTIAHVV-IDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEE 546
++KG A +V IDG G I I+D +K +A LA LK +GV V ++TGD+R A
Sbjct: 1159 DHEMKGQTAILVAIDGVLCGMIAIADAVKPEAALASITLKSMGV-DVALITGDNRKTARA 1217
Query: 547 IAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGAL 606
IA Q+G++ +AE+LP KV +++L+ KG K+ VGDG+ND+P LA+ADVG+A+G
Sbjct: 1218 IATQVGINKVFAEVLPSHKVAKVQELQN-KGK-KVAMVGDGVNDSPALAQADVGIAIGT- 1274
Query: 607 GSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFAL-----GVKLA---FIGL 658
G+D AI+ ADVV++ + + +I ++++T R + N++ AL G+ +A F+ +
Sbjct: 1275 GTDVAIDAADVVLIRNDLLDVVASIHLSKRTVRRIRVNLVLALIYNMVGIPIAAGVFMPI 1334
Query: 659 GIFGKATMWEAVFADVGVAL 678
GI + M A + V V L
Sbjct: 1335 GIVLQPWMGSAAASSVSVVL 1354
>gi|6680758 ATPase, Cu++ transporting, beta polypeptide; Wilson protein [Mus
musculus] >gi|1209657|gb|AAC52852.1| (U38477)
copper-transporting P-type ATPase [Mus musculus]
Length = 1462
Score = 282 bits (714), Expect = 9e-75
Identities = 226/808 (27%), Positives = 391/808 (47%), Gaps = 145/808 (17%)
Query: 5 KLKLEGLDCASCAYEIEEAL-RKEGFKFAVVNFATKEAIIEGDIEKA--KEVIKKVEPDV 61
+L + G+ CASC + IE L R G +A V AT +A ++ D E +++IK
Sbjct: 569 ELIITGMTCASCVHNIESKLTRTNGITYASVALATSKAHVKFDPEIVGPRDIIK------ 622
Query: 62 EVVEEVHIH-------------DHAHGEFEKRTIYFIGISLVLFTIGILM---------R 99
++EE+ H DH + + + + + +G+++ +
Sbjct: 623 -IIEEIGFHASLAQRNPNAHHLDHKTEIKQWKKSFLCSLVFGIPVMGLMVYMLIPSSTPQ 681
Query: 100 YYYAIDNTLVFGLFLASYL----------ISGWKVLKSAIVNSLNGNVFDENFLIAVATI 149
+D+ ++ GL + + + + GW A SL + + LI +AT
Sbjct: 682 ETMVLDHNIIPGLSVLNLIFFILCTFVQFLGGWYFYVQAY-KSLRHRSANMDVLIVLATT 740
Query: 150 GAFLIKEYPEGVAV------------------MLFYVIGEFLQDMAVDKSRRSIKALLAL 191
A+ VAV +F +G +L+ +A K+ ++ L++L
Sbjct: 741 IAYAYSLVILVVAVAEKAEKSPVTFFDTPPMLFVFIALGRWLEHVAKSKTSEALAKLMSL 800
Query: 192 KAEYANLV---RDGTVVK---VKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALT 245
+A A +V D +++ V E ++ GD+I V PG K PVDG ++EG + D S +T
Sbjct: 801 QATEATVVTLGEDNLILREEQVPMELVQRGDVIKVVPGGKFPVDGKVLEGNTMADESLIT 860
Query: 246 GESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFIT 305
GE+MP T K G +++G IN G + ++ T +++T+++I++LVE A KA ++
Sbjct: 861 GEAMPVTKKPGSIVIAGSINAHGSVLLKATHVGNDTTLAQIVKLVEEAQMSKAPIQQLAD 920
Query: 306 RFAHYYTPAVVGIATLIATVPPLVFKESF----------------TSWVYR-----ALVI 344
RF+ Y+ P ++ I+TL V ++ F T + R ++ +
Sbjct: 921 RFSGYFVPFIIIISTLTLVVWIVIGFVDFGVVQKYFPSPSKHISQTEVIIRFAFQTSITV 980
Query: 345 LVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFK 404
L I+CPC+L L+ P G G AA+ G+LIKG L+ V FDKTGT+T GV +
Sbjct: 981 LCIACPCSLGLATPTAVMVGTGVAAQNGVLIKGGKPLEMAHKIKTVMFDKTGTITHGVPR 1040
Query: 405 VTKIETRNGFTE---EEILRFAALAEAHSNHPIAKAIREAYGKEINEAEI---TEYEEIA 458
V + ++L AEA S HP+ A+ + +E+ + T+++ +
Sbjct: 1041 VMRFLLLADVATLPLRKVLAVVGTAEASSEHPLGVAVTKYCKEELGTETLGYSTDFQAVP 1100
Query: 459 GHGVRARIDSVE------------------------------VMVGNDKLLHRSNIEHDT 488
G G+ ++ +VE V++GN + + R+ + +
Sbjct: 1101 GCGISCKVSNVEGILARSDLTAHPVGVGNPPTGEGAGPQTFSVLIGNREWMRRNGLTISS 1160
Query: 489 C--------KVKGTIAHVV-IDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGD 539
++KG A +V IDG G I I+D +K +A LA+ LK +GV V ++TGD
Sbjct: 1161 DISDAMTDHEMKGQTAILVAIDGVLCGMIAIADAVKPEAALAIYTLKSMGV-DVALITGD 1219
Query: 540 SRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADV 599
+R A IA Q+G++ +AE+LP KV +++L+ E K+ VGDG+ND+P LA+ADV
Sbjct: 1220 NRKTARAIATQVGINKVFAEVLPSHKVAKVQELQNE--GKKVAMVGDGVNDSPALAQADV 1277
Query: 600 GVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFAL-----GVKLA 654
G+A+G G+D AIE ADVV++ + + +I ++++T R + N++ AL G+ +A
Sbjct: 1278 GIAIGT-GTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIRVNLVLALIYNMVGIPIA 1336
Query: 655 ---FIGLGIFGKATMWEAVFADVGVALI 679
F+ +GI + M A A V+++
Sbjct: 1337 AGVFMPIGIVLQPWMGSAAMAASSVSVV 1364
>emb|CAB65641.1| (AL136149) probable cation-transporting ATPase. [Streptomyces
coelicolor A3(2)]
Length = 762
Score = 280 bits (710), Expect = 3e-74
Identities = 183/538 (34%), Positives = 291/538 (54%), Gaps = 20/538 (3%)
Query: 161 VAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKP-EELKVGDIII 219
V V LF + G +L+ A + +++AL L + VRDGT + P EEL+VG + +
Sbjct: 211 VGVPLFVLAGRYLEARARRGTGAALRALAELAVKEV-AVRDGTGGRRIPIEELRVGQVFV 269
Query: 220 VKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELS 279
V+PGE+V DG ++EG+S+VD S +TGES P V G +++G +N+ GLL VR T +
Sbjct: 270 VRPGERVATDGTVVEGSSAVDLSLVTGESEPAEVAPGTAVIAGGVNVGGLLAVRATAVGA 329
Query: 280 ESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPP--LVFKESFTSW 337
++ ++RI LV A A KA+ ++ + A + P V+ TL ATV L +
Sbjct: 330 DTRLARITHLVTEAQAGKARAQRLADKVAGVFVPVVL---TLAATVLGFWLGAGADPQAA 386
Query: 338 VYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGT 397
+ ++ +LV++CPCAL L+ P GR A+ G+L+ G L+ L+ +V DKTGT
Sbjct: 387 ITASVAVLVVACPCALGLATPTALMAATGRGAQLGVLVSGPQALEGLRHIDVVVLDKTGT 446
Query: 398 LTKGVFKVTKIETR-NGFTEEEILRFAALAEAHSNHPIAKAIREAYGKEI----NEAEIT 452
LT G V ++ G EE+ +R A E S HP+ +A+ AY + + E+T
Sbjct: 447 LTSGHMSVARVTAMPRGIGEEQAVRLAGAVEQGSEHPLGQAV-TAYARRTMPTGSLPEVT 505
Query: 453 EYEEIAGHGVRARIDS--VEVMVGNDKL-LHRSNIEHDTCKVKGTIAHVVIDGQYAGYIV 509
++ + G GVR R++ VEV +D+L + T V +DG G I
Sbjct: 506 DFAALPGRGVRGRVEGRLVEVTAPDDELPVPLDEAMSGAESAAHTPVVVRVDGVTEGLIE 565
Query: 510 ISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKII 569
+ D ++ ++ AV L+RLGVR V+ TGD A +A L +D +A PEDK +++
Sbjct: 566 VGDVLRPGSYRAVDRLRRLGVRP-VLATGDREAPARAVATALRIDDVHARRTPEDKARLV 624
Query: 570 EKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPK 629
+L +E ++ VGDG+NDA LA AD+G+AMG G+DAAI ADV ++ L
Sbjct: 625 RELREE--GHRVAVVGDGVNDAAALAGADLGIAMGT-GTDAAIGAADVTLVRGDIDALAD 681
Query: 630 AIQIARKTQRIVWENIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIAVFNAMRV 687
A++++R T + N+++A G + + + G + A +L+ V N++R+
Sbjct: 682 AVRLSRSTLATIRVNLLWAFGYNVVTMPPAMVGLLSPMPAAAVMSVSSLLVVGNSLRL 739
>pir||S40525 copper-transporting ATPase (EC 3.6.1.-) beta chain - human
Length = 1411
Score = 280 bits (709), Expect = 3e-74
Identities = 232/811 (28%), Positives = 389/811 (47%), Gaps = 146/811 (18%)
Query: 5 KLKLEGLDCASCAYEIEEAL-RKEGFKFAVVNFATKEAIIEGDIEKAKEVIKKVEPDVEV 63
+L + G+ CASC + IE L R G +A V AT +A+++ D E I + +
Sbjct: 536 ELTITGMTCASCVHNIESKLTRTNGITYASVALATSKALVKFDPE-----IIGPRDIIII 590
Query: 64 VEEVHIH-------DHAHGEFEKRTI----------YFIGISLVLFTIGILM-----RYY 101
+EE+ H +AH K I GI ++ I +L+
Sbjct: 591 IEEIGFHASLAQRNPNAHHLDHKMEIKQWKKSFLCSLVFGIPVMALMIYMLIPSNEPHQS 650
Query: 102 YAIDNTLVFGLFLASY----------LISGWKVLKSAIVNSLNGNVFDENFLIAVATIGA 151
+D+ ++ GL + + L+ GW A SL + + LI +AT A
Sbjct: 651 MVLDHNIIPGLSILNLIFFILCTFVQLLGGWYFYVQAY-KSLGHRSANMDVLIVLATSIA 709
Query: 152 FLIKEYPEGVAV------------------MLFYVIGEFLQDMAVDKSRRSIKALLALKA 193
++ VAV +F +G +L+ +A K+ ++ L++L+A
Sbjct: 710 YVYSLVILVVAVAEKAERSPVTFFDTPPMLFVFIALGRWLEHLAKSKTSEALAKLMSLQA 769
Query: 194 EYANLV---RDGTVVK---VKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGE 247
A +V D +++ V E ++ GDI+ V PG K PVDG ++EG + D S +TGE
Sbjct: 770 TEATVVTLGEDNLIIREEQVPMELVQRGDIVKVVPGGKFPVDGKVLEGNTMADESLITGE 829
Query: 248 SMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRF 307
+MP T K G +++G IN G + ++ T +++T+++I++LVE A KA ++ RF
Sbjct: 830 AMPVTKKPGSTVIAGSINAHGSVPIKATHVGNDTTLAQIVKLVEEAQMSKAPIQQLADRF 889
Query: 308 AHYYTPAVVGIATLIATVPPLVFKESF-------------------TSWV--YRALVILV 346
+ Y+ P ++ ++TL V ++ F W ++ +L
Sbjct: 890 SGYFVPFIIIMSTLTLVVWIVIGFIDFGVVQRYFPNPNKHISQTEVIIWFAFQTSITVLC 949
Query: 347 ISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVT 406
I+CPC+L L+ P G G AA+ GILIKG L+ V FDKTGT+ GV +V
Sbjct: 950 IACPCSLGLATPTAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKTGTIIHGVPRVM 1009
Query: 407 KIETRNGFTE---EEILRFAALAEAHSNHPIAKAIREAYGKEINEAEI---TEYEEIAGH 460
++ ++L AEA S HP+ A+ + +E+ + T+++ + G
Sbjct: 1010 RVLLLGDVATLPLRKVLAVVGTAEASSEHPLGVAVTKYCKEELGTETLGYCTDFQAVPGC 1069
Query: 461 GVRARIDSVE-----------------------------------VMVGNDKLLHRSN-- 483
G+ ++ + E V++GN + L R+
Sbjct: 1070 GIGCKVSNAEDILAHSERPLSAPASHLNEAGSLPAEKDAAPQTFSVLIGNREWLRRNGLT 1129
Query: 484 IEHDTC------KVKGTIAHVV-IDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMV 536
I D ++KG A +V IDG G I I+D +K++A LAV L+ +GV VV++
Sbjct: 1130 ISSDVSDAMTDHEMKGQTAILVAIDGVLCGMIAIADAVKQEAALAVHTLQSMGV-DVVLI 1188
Query: 537 TGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLAR 596
TGD+R A IA Q+G++ +A +LP KV +++L+ KG K+ VGDG+ND+P LA+
Sbjct: 1189 TGDNRKTARAIATQVGINKVFAGVLPSHKVAKVQELQN-KGK-KVAMVGDGVNDSPALAQ 1246
Query: 597 ADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFAL-----GV 651
AD+GVA+G G+D AIE ADVV++ + + +I ++++T R + N++ AL G+
Sbjct: 1247 ADMGVAIGT-GTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIRINLVLALIYNLVGI 1305
Query: 652 KLA---FIGLGIFGKATMWEAVFADVGVALI 679
+A F+ +GI + M A A V+++
Sbjct: 1306 PIAAGVFMPIGIVLQPWMGSAAMAASSVSVV 1336
>prf||2001422A Cu transporting ATPase P [Homo sapiens]
Length = 1411
Score = 280 bits (709), Expect = 3e-74
Identities = 232/811 (28%), Positives = 389/811 (47%), Gaps = 146/811 (18%)
Query: 5 KLKLEGLDCASCAYEIEEAL-RKEGFKFAVVNFATKEAIIEGDIEKAKEVIKKVEPDVEV 63
+L + G+ CASC + IE L R G +A V AT +A+++ D E I + +
Sbjct: 536 ELTITGMTCASCVHNIESKLTRTNGITYASVALATSKALVKFDPE-----IIGPRDIIII 590
Query: 64 VEEVHIH-------DHAHGEFEKRTI----------YFIGISLVLFTIGILM-----RYY 101
+EE+ H +AH K I GI ++ I +L+
Sbjct: 591 IEEIGFHASLAQRNPNAHHLDHKMEIKQWKKSFLCSLVFGIPVMALMIYMLIPSNEPHQS 650
Query: 102 YAIDNTLVFGLFLASY----------LISGWKVLKSAIVNSLNGNVFDENFLIAVATIGA 151
+D+ ++ GL + + L+ GW A SL + + LI +AT A
Sbjct: 651 MVLDHNIIPGLSILNLIFFILCTFVQLLGGWYFYVQAY-KSLGHRSANMDVLIVLATSIA 709
Query: 152 FLIKEYPEGVAV------------------MLFYVIGEFLQDMAVDKSRRSIKALLALKA 193
++ VAV +F +G +L+ +A K+ ++ L++L+A
Sbjct: 710 YVYSLVILVVAVAEKAERSPVTFFDTPPMLFVFIALGRWLEHLAKSKTSEALAKLMSLQA 769
Query: 194 EYANLV---RDGTVVK---VKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGE 247
A +V D +++ V E ++ GDI+ V PG K PVDG ++EG + D S +TGE
Sbjct: 770 TEATVVTLGEDNLIIREEQVPMELVQRGDIVKVVPGGKFPVDGKVLEGNTMADESLITGE 829
Query: 248 SMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRF 307
+MP T K G +++G IN G + ++ T +++T+++I++LVE A KA ++ RF
Sbjct: 830 AMPVTKKPGSTVIAGSINAHGSVPIKATHVGNDTTLAQIVKLVEEAQMSKAPIQQLADRF 889
Query: 308 AHYYTPAVVGIATLIATVPPLVFKESF-------------------TSWV--YRALVILV 346
+ Y+ P ++ ++TL V ++ F W ++ +L
Sbjct: 890 SGYFVPFIIIMSTLTLVVWIVIGFIDFGVVQRYFPNPNKHISQTEVIIWFAFQTSITVLC 949
Query: 347 ISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVT 406
I+CPC+L L+ P G G AA+ GILIKG L+ V FDKTGT+ GV +V
Sbjct: 950 IACPCSLGLATPTAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKTGTIIHGVPRVM 1009
Query: 407 KIETRNGFTE---EEILRFAALAEAHSNHPIAKAIREAYGKEINEAEI---TEYEEIAGH 460
++ ++L AEA S HP+ A+ + +E+ + T+++ + G
Sbjct: 1010 RVLLLGDVATLPLRKVLAVVGTAEASSEHPLGVAVTKYCKEELGTETLGYCTDFQAVPGC 1069
Query: 461 GVRARIDSVE-----------------------------------VMVGNDKLLHRSN-- 483
G+ ++ + E V++GN + L R+
Sbjct: 1070 GIGCKVSNAEDILAHSERPLSAPASHLNEAGSLPAEKDAAPQTFSVLIGNREWLRRNGLT 1129
Query: 484 IEHDTC------KVKGTIAHVV-IDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMV 536
I D ++KG A +V IDG G I I+D +K++A LAV L+ +GV VV++
Sbjct: 1130 ISSDVSDAMTDHEMKGQTAILVAIDGVLCGMIAIADAVKQEAALAVHTLQSMGV-DVVLI 1188
Query: 537 TGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLAR 596
TGD+R A IA Q+G++ +A +LP KV +++L+ KG K+ VGDG+ND+P LA+
Sbjct: 1189 TGDNRKTARAIATQVGINKVFAGVLPSHKVAKVQELQN-KGK-KVAMVGDGVNDSPALAQ 1246
Query: 597 ADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFAL-----GV 651
AD+GVA+G G+D AIE ADVV++ + + +I ++++T R + N++ AL G+
Sbjct: 1247 ADMGVAIGT-GTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIRINLVLALIYNLVGI 1305
Query: 652 KLA---FIGLGIFGKATMWEAVFADVGVALI 679
+A F+ +GI + M A A V+++
Sbjct: 1306 PIAAGVFMPIGIVLQPWMGSAAMAASSVSVV 1336
>pir||S76487 probable copper-transporting ATPase (EC 3.6.1.-) - Synechocystis
sp. (strain PCC 6803) >gi|1653704|dbj|BAA18616.1|
(D90915) cation-transporting P-type ATPase
[Synechocystis sp.]
Length = 780
Score = 280 bits (709), Expect = 3e-74
Identities = 209/719 (29%), Positives = 358/719 (49%), Gaps = 81/719 (11%)
Query: 6 LKLEGLDCASCAYEIEEALRK-EGFKFAVVNFATKEAIIEGDIEKAK-EVIKKVEPDVEV 63
L + G+ CA C +E L + G + VN T A++ + EK + + I +
Sbjct: 28 LDVGGMKCAGCVAAVERQLDQLTGVTDSCVNLVTAVAVVRYEPEKIQPQAIAEHLSQRGF 87
Query: 64 VEEVHIHDHAHG---------EFEKRTIYFIGISLVLFTIG-----------ILMRYYYA 103
++ H HG E + + + I+LVL + ++ +++
Sbjct: 88 PSQIR---HGHGAIPATIGEKETRENVNWGLTIALVLLLLSGLGHLSHFGGPMIPFFHHP 144
Query: 104 IDN----TLVFGLFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIK---- 155
I + TL + + GW+ L+ N N L+A+ T A+L
Sbjct: 145 IFHWSLATLAIAIPGREIFLDGWRGLRFGHANM--------NTLVALGTGSAYLTSCIAW 196
Query: 156 ---------EYPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRDG---- 202
+ E V ++ ++G L+ A K++ ++ LLAL+ A LV G
Sbjct: 197 AWPGLGWECFFDEPVMLLGMLLLGRTLESKARQKAKSALTELLALQPSLARLVGRGEDQG 256
Query: 203 -TVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILS 261
T +++ E+++VG+ + V PGEK+PVDG+++ G + VD S LTGES+P D +++
Sbjct: 257 ETGIEIPVEQVRVGEWVQVLPGEKIPVDGILVAGKTLVDESLLTGESLPVAKNVDDAVIA 316
Query: 262 GMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATL 321
G N +G + + T +E+T++RI++LVE A +KA ++ + A ++ V+ IA +
Sbjct: 317 GAWNQSGAIIIAATHIGAETTLARIIQLVETAQTQKAPMQRLADQVAGWFAYGVLAIALV 376
Query: 322 IATVPPLVFKESFTSWV------------YRALVILVISCPCALVLSIPLGYFGGIGRAA 369
+V + F V ++ +LV++CPCAL L+ P G A
Sbjct: 377 TLGFWAMVGQSLFPEMVADTGLSPLLLALKLSVSVLVVACPCALGLATPTAILVGTSLGA 436
Query: 370 KEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAH 429
++GILIKG N L+ L+ +++AFDKTGTLT+G ++T T E+L AA E
Sbjct: 437 EQGILIKGGNILEILQRTTVMAFDKTGTLTQGNLQLTDAVPVADITGIELLTLAASVEQG 496
Query: 430 SNHPIAKA-IREAYGKEINEAEITEYEEIAGHGVRARIDSVEVMVGNDKLLHRSNI---- 484
+ HP+A+ I A G E+ E E E AG GV+ ++VGN + L +
Sbjct: 497 TRHPLAQGLISSAQGLELLPVENIETE--AGQGVQGWYQGDRLLVGNQQWLMEQGVMGEP 554
Query: 485 ----EHDTCKVKG-TIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGD 539
D +G T+ V + Q G++ + D ++ +A + +LK+ G+ +++TGD
Sbjct: 555 QWQTAVDQLLDQGKTVIFVARNQQLQGFLALRDTLRPEAKATIAQLKQWGIAP-LLLTGD 613
Query: 540 SRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADV 599
+A+ IA ++G++ F A++ P+ KV I+ ++ + VGDGINDAP LA+ADV
Sbjct: 614 HPAIAQAIAMEVGIEEFQAQMTPQAKVAKIKAMQGFNPVSVIAMVGDGINDAPALAQADV 673
Query: 600 GVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGL 658
G+++ + A+ETADVV+M S + KA+ ++R T + +N+++ALG L I L
Sbjct: 674 GISLSG-ATAVAMETADVVLMRSHLSDVLKALTLSRSTVAKIKQNLLWALGYNLLAIPL 731
>gb|AAB02268.1| (U58330) probable copper-transporting atpase [Escherichia coli]
Length = 834
Score = 280 bits (709), Expect = 3e-74
Identities = 221/742 (29%), Positives = 368/742 (48%), Gaps = 69/742 (9%)
Query: 4 RKLKLEGLDCASCAYEIEEALRK-EGFKFAVVNFATKEAIIEGD---------IEKAKEV 53
++L L G+ CASC ++ AL+ G A VN A + A++ G +EKA
Sbjct: 101 QQLLLSGMSCASCVTRVQNALQSVPGVTQARVNLAERTALVMGSASPQDLVQAVEKAGYG 160
Query: 54 IKKVEPDVEVVEEVHIHDH-AHGEFEKRTIYFIGISLVLFTIGILM-RYYYAIDNT---L 108
K+++ + A F + I + + + + G++ DN L
Sbjct: 161 AKRLKMTLNAASASKKPPSLAMKRFRWQAIVALAVGIPVMVWGMIGDNMMVTADNRSLWL 220
Query: 109 VFGLF-LASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKE----------- 156
V GL LA + +G +SA + LNG + L+A+ T A+L
Sbjct: 221 VIGLITLAVMVFAGGHFYRSAWKSLLNGAATMDT-LVALGTGVAWLYSMSVNLWPQWFPM 279
Query: 157 -----YPEGVAVMLFYV-IGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPE 210
Y E A+++ + +G L+ A +S ++++ LL L A LV D V
Sbjct: 280 EARHLYYEASAMIIGLINLGHMLEARARQRSSKALEKLLDLTPPTARLVTDEGEKSVPLA 339
Query: 211 ELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLL 270
E++ G ++ + G++VPVDG I +G + +D + LTGE +P+ EGD + +G + G +
Sbjct: 340 EVQPGMLLRLTTGDRVPVDGEITQGEAWLDEAMLTGEPIPQQKGEGDSVHAGTVVQDGSV 399
Query: 271 KVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATV----- 325
R + S +T+SRI+ +V A + K + + + + + P VV IA + A +
Sbjct: 400 LFRASAVGSHTTLSRIIRMVRQAQSSKPEIGQLADKISAVFVPVVVVIALVSAAIWYFFG 459
Query: 326 --PPLVFKESFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDA 383
P +V+ + A +L+I+CPCAL L+ P+ G+GRAA+ G+L++ + L
Sbjct: 460 PAPQIVYT------LVIATTVLIIACPCALGLATPMSIISGVGRAAEFGVLVRDRDALQR 513
Query: 384 LKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYG 443
V FDKTGTLT+G +V ++T E + LR AA E S+HP+A+AI + G
Sbjct: 514 ASTLDTVVFDKTGTLTEGKPQVVAVKTFADVDEAQALRLAAALEQGSSHPLARAILDKAG 573
Query: 444 KEINEAEITEYEEIAGHGVRARIDSVEVMVGNDKLLHRSNIEHDTCKVK--------GTI 495
++ ++ + + G GV + +++GN LL+ + + + T
Sbjct: 574 -DMRLPQVNGFRTLRGLGVSGEAEGHALLLGNQALLNEQQVGTKAIEAEITAQASQGATP 632
Query: 496 AHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDG 555
+ +DG+ + + D ++ D+ A++ L + G R +VM+TGD+ A IAK+ G+D
Sbjct: 633 VLLAVDGKAVALLAVRDPLRSDSVAALQRLHKAGYR-LVMLTGDNPTTANAIAKEAGIDE 691
Query: 556 FYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETA 615
A +LP+ K + I+ L+ E ++ VGDGINDAP LA+ADVG+AMG GSD AIETA
Sbjct: 692 VIAGVLPDGKAEAIKHLQSE--GRQVAMVGDGINDAPALAQADVGIAMGG-GSDVAIETA 748
Query: 616 DVVIMDDKPSKLPKAIQIARKTQRIVWENIIFA-----LGVKLAFIGLGIFGKATMWEAV 670
+ +M + A+ I+R T + +N++ A +G+ +A L F T+ V
Sbjct: 749 AITLMRHSLMGVADALAISRATLHNMKQNLLGAFIYNSIGIPVAAGILWPF-TGTLLNPV 807
Query: 671 FADVGVAL---IAVFNAMRVLR 689
A +AL V NA R+LR
Sbjct: 808 VAGAAMALSSITVVSNANRLLR 829
>pir||T36946 probable cation-transporting ATPase - Streptomyces coelicolor
>gi|5748626|emb|CAB53131.1| (AL109962) putative
cation-transporting ATPase [Streptomyces coelicolor
A3(2)]
Length = 776
Score = 278 bits (704), Expect = 1e-73
Identities = 179/554 (32%), Positives = 283/554 (50%), Gaps = 19/554 (3%)
Query: 143 LIAVATIGAFL-IKEYPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRD 201
LIAV +G L + EY GV + L G L+ A ++ + ALLA A
Sbjct: 81 LIAVLALGGTLAVGEYLAGVLIALMLATGRTLEGAAQRRASHDLHALLAHAPRSARRRTG 140
Query: 202 GTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILS 261
VV+V E+ GD ++V PGE VPVDG + + +D S LTGE + T + G+ S
Sbjct: 141 DGVVRVPLSEITAGDALVVGPGEVVPVDGRVESTEAVLDESVLTGEPLQVTRQRGEGARS 200
Query: 262 GMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATL 321
G +N G +R T +ST + I+ L + A A A + R+A ++ P + A L
Sbjct: 201 GAVNAGGAFDLRATAIEQDSTYAGIVRLAQQAGAESAPVVRLADRYAAWFLPLALATAAL 260
Query: 322 IATVPPLVFKESFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYL 381
V + RA+ +LV++ PC L+L+ P+ G+ RA++ G++++ L
Sbjct: 261 AWLV---------SGSAVRAVAVLVVATPCPLLLAAPVAVVSGLSRASRRGVVVRDGGAL 311
Query: 382 DALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIRE- 440
+ L A + DKTGTLT G V + G E+LR AA + S H +A+AI +
Sbjct: 312 ENLGRARTLLLDKTGTLTVGRPCVLDVVAAPGHVPAEVLRVAASLDQLSPHVLAQAIVDA 371
Query: 441 AYGKEINEAEITEYEEIAGHGVRARIDSVEVMVG-NDKLLHRSN----IEHDTCKVKGTI 495
A + + + TE E G G ++ V +G +D R N + + ++
Sbjct: 372 ARTRRLELSAPTEVTEEPGRGASGVVEGHRVFIGRDDPTRARPNWAKAVGNRALLDGASV 431
Query: 496 AHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDG 555
A + +D + G +++ D ++ DA AV+ L+ G+ ++VM+TGD A+E+A LGLDG
Sbjct: 432 AWLTVDERLTGAVLLRDALRRDAPHAVRRLRSAGIERLVMLTGDRAATAQEVAAVLGLDG 491
Query: 556 FYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETA 615
AEL P DKV + E+ + V VGDG+NDAP LA AD+GVAMGA G+ A+ E A
Sbjct: 492 VRAELGPADKVAAV---RGEREHAVTVMVGDGVNDAPALAAADIGVAMGARGTTASSEAA 548
Query: 616 DVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGLGIFGKATMWEAVFADVG 675
D+V+ D+ +L A+ IA++++RI ++ + + + L + G G
Sbjct: 549 DIVLTTDRVDRLADAVVIAQRSRRIAVQSALGGMLLSLGAMAAAALGLIQPAAGALLQEG 608
Query: 676 VALIAVFNAMRVLR 689
+ + + NA+R LR
Sbjct: 609 IDVAVILNALRALR 622
>sp|P05425|COPB_ENTHR COPPER/POTASSIUM-TRANSPORTING ATPASE B >gi|538894|pir||B45995
copper-transporting ATPase (EC 3.6.1.-) copB -
Enterococcus hirae >gi|290643|gb|AAA61836.1| (L13292)
ATPase [Enterococcus hirae]
Length = 745
Score = 277 bits (702), Expect = 2e-73
Identities = 184/567 (32%), Positives = 311/567 (54%), Gaps = 35/567 (6%)
Query: 127 SAIVNSLNGNVFDENFLIAVATIGAFLIKEYPEGVAVMLFYVIGEFLQDMAVDKSRRSIK 186
S I N +N + +F +AT+ + +ML +G +++ AV + +++
Sbjct: 189 SFIANLINPHTHVMDFFWELATL-----------IVIML---LGHWIEMNAVSNASDALQ 234
Query: 187 ALLALKAEYAN-LVRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALT 245
L L E L +DGT V +E+ GD +IV+ G+K+P DG I +G + VD SA+T
Sbjct: 235 KLAELLPESVKRLKKDGTEETVSLKEVHEGDRLIVRAGDKMPTDGTIDKGHTIVDESAVT 294
Query: 246 GESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFIT 305
GES + GD ++ G IN G +++ VT +++++E+V A K+K E
Sbjct: 295 GESKGVKKQVGDSVIGGSINGDGTIEITVTGTGENGYLAKVMEMVRKAQGEKSKLEFLSD 354
Query: 306 RFAH--YYTPAVVGIATLIATVPPLVFKESFTSWVYRALVILVISCPCALVLSIPLGYFG 363
+ A +Y VVGI IA +F + + R + + +I+CP AL L+IPL
Sbjct: 355 KVAKWLFYVALVVGIIAFIA----WLFLANLPDALERMVTVFIIACPHALGLAIPLVVAR 410
Query: 364 GIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRN-GFTEEEILRF 422
AAK G+L+K N ++ D ++ DKTGTLT+G F VT IE + + EEEIL++
Sbjct: 411 STSIAAKNGLLLKNRNAMEQANDLDVIMLDKTGTLTQGKFTVTGIEILDEAYQEEEILKY 470
Query: 423 AALAEAHSNHPIAKAIRE-AYGKEINEAEITEYEEIAGHGVRARIDSVEVMVGNDKLLHR 481
EAH+NHP+A I K+I + E + +AG G+ A ++ +V + N+K R
Sbjct: 471 IGALEAHANHPLAIGIMNYLKEKKITPYQAQEQKNLAGVGLEATVEDKDVKIINEKEAKR 530
Query: 482 SNIEHDTCKVK------GTIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVM 535
++ D ++K T++ +V+ + I + D IK +A ++ +K + VM
Sbjct: 531 LGLKIDPERLKNYEAQGNTVSFLVVSDKLVAVIALGDVIKPEAKEFIQAIKEKNIIP-VM 589
Query: 536 VTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEK-LEKEKGNGKLVFVGDGINDAPVL 594
+TGD+ A+ +A+ LG++ +Y LLP+DK I+++ L++ K K++ VGDGINDAP L
Sbjct: 590 LTGDNPKAAQAVAEYLGINEYYGGLLPDDKEAIVQRYLDQGK---KVIMVGDGINDAPSL 646
Query: 595 ARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLA 654
ARA +G+A+GA G+D AI++ADVV+ + P + +++A++T+R + +N+ + G +
Sbjct: 647 ARATIGMAIGA-GTDIAIDSADVVLTNSDPKDILHFLELAKETRRKMIQNLWWGAGYNII 705
Query: 655 FIGLGIFGKATMWEAVFADVGVALIAV 681
I L A + + VG L+++
Sbjct: 706 AIPLAAGILAPIGLILSPAVGAVLMSL 732
>sp|P77868|Y290_HAEIN PROBABLE CATION-TRANSPORTING ATPASE HI0290
>gi|1573258|gb|AAC21955.1| (U32715)
potassium/copper-transporting ATPase, putative
[Haemophilus influenzae Rd]
Length = 722
Score = 277 bits (701), Expect = 3e-73
Identities = 202/716 (28%), Positives = 366/716 (50%), Gaps = 44/716 (6%)
Query: 6 LKLEGLDCASCAYEIEEALRKEGF-KFAVVNFATKEAIIEGDIEKAKE-----VIKKV-- 57
+++ G+ C SCA IE+ L K+ F + A VNFA +EA + D +A E +I K
Sbjct: 13 IQIGGMTCQSCANRIEKVLNKKPFVQQAGVNFAAEEAQVVFDATQASEAQIIEIIHKTGF 72
Query: 58 EPDVEVVEEVHIHDHAHGEFEKRTIYFIGISLVLFTIGILMRYYYAIDNTLVFGLFLASY 117
++ E+ I ++ + ++ I I ++ +G++ + + + F +
Sbjct: 73 SAHIKQANELPIEENTSIPWRLIVLWIINIPFLIGMLGMIGGSHNLMLPPI--WQFALAS 130
Query: 118 LISGWKVLK--SAIVNSLNGNVFDENFLIAVATIGAFLIKEY---------------PEG 160
++ W + + S+ G + + + L++ T+ +L +
Sbjct: 131 IVQLWLAIPFYRGAIGSIRGGLTNMDVLVSTGTLTIYLYSAFMLFYHANHAMGHVYFEAS 190
Query: 161 VAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIV 220
V V+ F +G+FL+D S S+ LL L + ++R+ +++ +++ +G+II
Sbjct: 191 VMVIGFVSLGKFLEDRTKKHSLNSLSMLLQLTPKKVTVLRNEKWIEIALDQVNIGEIIRA 250
Query: 221 KPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSE 280
GE++ DGVI G D S LTGES P ++G ++L+G + G + R + S+
Sbjct: 251 NQGERIAADGVIESGNGWCDESHLTGESRPEEKQKGGKVLAGAMVTEGSIIYRANQLGSQ 310
Query: 281 STVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKESFTSWVYR 340
+ + ++ + +A KA +F + + P V+ I+ + + ++ +S +S ++
Sbjct: 311 TLLGDMMNALSDAQGSKAPIARFADKVTSVFVPVVLVISLVTFALTYILTNDSVSSLIH- 369
Query: 341 ALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTK 400
A+ +LVI+CPCAL L+ P G+G+A G+ K + ++ V DKTGTLTK
Sbjct: 370 AVSVLVIACPCALGLATPAAIMVGLGKAVNAGVWFKDAAAMEETAHVDTVVLDKTGTLTK 429
Query: 401 GVFKVTKIETRNG--FTEEEILRFAALAEAHSNHPIAKAIREAYGKEINEAEITEYEEI- 457
G +++ + ++E+++ RFAA E +NHPIAKAI +A ++ E + ++
Sbjct: 430 GELEISALWQPQSAVYSEDDLYRFAAAVERQANHPIAKAIVQAAEXKMLEIPTALFSKME 489
Query: 458 AGHGVRARIDSV-EVMVGNDK---LLHRSNIEHDTCKVKGTIAHVVIDGQYAGYIVISDE 513
G G++A ++ V + VG L+ N+E D ++ +A V I+ + G ++D
Sbjct: 490 VGQGIQAELEQVGTIKVGKPDYCGLILPKNLE-DIWQIASIVA-VSINDEPIGAFALTDT 547
Query: 514 IKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLE 573
+K D+ A++ L++ + VV+++GD + V + IAKQLG+ + +L P DK + I+KL
Sbjct: 548 LKNDSLHAIQRLQQQNI-DVVIMSGDQQSVVDYIAKQLGIKKAFGKLTPRDKAEQIQKL- 605
Query: 574 KEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQI 633
K+ G+ + VGDGINDAP LA A+V AM + SD A +TA +M ++L A+ I
Sbjct: 606 KDLGH-IVAMVGDGINDAPALASANVSFAMKS-SSDIAEQTASATLMQHSVNQLVDALFI 663
Query: 634 ARKTQRIVWENIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIAVFNAMRVLR 689
AR T + + +N+ FAL + I L FG + A +AL ++ M LR
Sbjct: 664 ARATLKNIKQNLFFALIYNILGIPLAAFG---FLSPIIAGAAMALSSISVLMNALR 716
>dbj|BAA96520.1| (AB044355) ORFG [Pseudomonas syringae]
Length = 794
Score = 276 bits (699), Expect = 5e-73
Identities = 214/721 (29%), Positives = 353/721 (48%), Gaps = 63/721 (8%)
Query: 6 LKLEGLDCASCAYEIEEALRK-EGFKFAVVNFATKEA--------IIEGDIEKAKEVIKK 56
L + G+ CASC +E ALRK G VN AT++A ++ I + +
Sbjct: 72 LSITGMTCASCVNRVERALRKVPGVGEVSVNLATEQAHVTAIAGTSVQALIAAVRNAGYQ 131
Query: 57 VEPDVEVVEEVHIHDHAHGEFEKRTIYFIGISLVL------FTIGILMRYY--YAIDNTL 108
+P V + + LVL I I++ + +A+ +
Sbjct: 132 AQPPTTKVPAAENTRLTQERWALIAALLLAAPLVLPMLLQPLGIHIMLPVWLQFALATPV 191
Query: 109 VFGLFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEYP---------- 158
F L A + + WK L++ GN+ + L+A+ T A+ + Y
Sbjct: 192 QF-LLGARFYRAAWKALRAR-----TGNM---DLLVALGTSAAYGLSVYQAVTAVPGQFP 242
Query: 159 ----EGVAVMLFYV-IGEFLQDMAVDKSRRSIKALLALKAEYA-NLVRDGTVVKVKPEEL 212
E AV++ V +G++L+ A ++ +I+AL L+ E A L DG +V +L
Sbjct: 243 HLYLEAAAVVIGLVRLGKYLESRAKRQTGEAIRALQGLRPERALRLEADGREQEVAVADL 302
Query: 213 KVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKV 272
++ + + V+PGE++PVDG+I G S D + ++GES P + GD+++ G IN G L V
Sbjct: 303 RLKERVRVRPGERIPVDGLIETGDSYADEALISGESRPVAKQAGDKVIGGSINGEGTLIV 362
Query: 273 RVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKE 332
+VT ES ++RI+ LVE+A A KA ++ + + + + P V+GIA L+ V L+
Sbjct: 363 QVTALGGESVLARIIRLVEDAQAAKAPIQRLVDKVSEIFVPVVLGIA-LLTLVGWLLAGS 421
Query: 333 SFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAF 392
+ + + A+ +LVI+CPCAL L+ P G G AA+ GILIK + L+ VAF
Sbjct: 422 DWETALINAVAVLVIACPCALGLATPTAIMAGTGVAARHGILIKDAQTLEVAHAVQAVAF 481
Query: 393 DKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKE-INEAEI 451
DKTGTLT G + + + E E L A + S HP+ +A+ A + ++
Sbjct: 482 DKTGTLTSGEPHLVHMAVAS-IPEAEALALAGRLQRGSEHPLGRAVLAACSERGLDTPMA 540
Query: 452 TEYEEIAGHGVRARIDSVEVMVGNDKLLHRSNIEHDTCKVKG--------TIAHVVIDG- 502
+ G GV+ ++ ++ +GN + L +E T++ ++ G
Sbjct: 541 DSVRALPGRGVQGSVEGRQLALGNGRWLEELGLEPGALAEHAQLWDAEGRTLSWLIELGA 600
Query: 503 --QYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAEL 560
+ + D +K A AV L + ++TGD+ A + A Q G++ +A++
Sbjct: 601 APRVLALLAFGDALKPGAQQAVAALAARQISS-HLITGDTWSSARQTAAQTGIENIHAQV 659
Query: 561 LPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIM 620
LP +K ++ L K KG ++ VGDGINDAP LA ADVG+AMG+ G+D A+ A + ++
Sbjct: 660 LPAEKAAVVAGL-KAKGT-RVAMVGDGINDAPALAAADVGIAMGS-GTDVAMHAAGITLL 716
Query: 621 DDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIA 680
P +P A+ IAR T R + +N+ +A + I L FG + + VFA +A +
Sbjct: 717 RSDPRLVPAALDIARCTHRKIRQNLFWAFVYNVIGIPLAAFG---LLDPVFAGAAMAFSS 773
Query: 681 V 681
V
Sbjct: 774 V 774
>sp|Q10877|CTPB_MYCTU CATION-TRANSPORTING P-TYPE ATPASE B >gi|7436407|pir||G70751
probable ctpB protein - Mycobacterium tuberculosis
(strain H37RV) >gi|1405774|emb|CAA98939.1| (Z74410) ctpB
[Mycobacterium tuberculosis] >gi|1518362|emb|CAA68915.1|
(Y07638) P-type ATPase [Mycobacterium tuberculosis]
Length = 752
Score = 276 bits (699), Expect = 5e-73
Identities = 218/743 (29%), Positives = 351/743 (46%), Gaps = 70/743 (9%)
Query: 4 RKLKLE--GLDCASCAYEIEEALRKEGFKFAVVNFATKEAIIEGDIEKAKEVIKKVE--- 58
R+++L+ G+ CA+CA +E L K A VNFAT+ A I+ A E+ VE
Sbjct: 15 RRIRLDVLGMSCAACASRVETKLNKIPGVRASVNFATRVATIDAVGMAADELCGVVEKAG 74
Query: 59 ----PDVEVVEEVHIHDHAHGEFEKRTIYFIGISLVLFT-IGILMRYYYAIDNTLVFG-- 111
P E G +R + + ++ VLF + L + + + V G
Sbjct: 75 YHAAPHTETTVLDKRTKDPDGAHARRLLRRLLVAAVLFVPLADLSTLFAIVPSARVPGWG 134
Query: 112 ---LFLASYLIS--GWKVLKSAIVNSLNGNVFDENFLIAVATIGAF-------------- 152
LA+ +++ W A+ N+ + E LI+V + A
Sbjct: 135 YILTALAAPVVTWAAWPFHSVALRNARHRTTSMET-LISVGIVAATAWSLSSVFGDQPPR 193
Query: 153 --------------LIKEYPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAE-YAN 197
+ E GV V F + G + + A K+ +++AL L A+ A
Sbjct: 194 EGSGIWRAILNSDSIYLEVAAGVTV--FVLAGRYFEARAKSKAGSALRALAELGAKNVAV 251
Query: 198 LVRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGD 257
L+ DG + + ELK + +PGE + DGV+++G++++D SA+TGE+ P
Sbjct: 252 LLPDGAELVIPASELKKRQRFVTRPGETIAADGVVVDGSAAIDMSAMTGEAKPVRAYPAA 311
Query: 258 EILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVG 317
++ G + + G L + T +++ + ++ LVE A +KA+ ++ A + P V
Sbjct: 312 SVVGGTVVMDGRLVIEATAVGADTQFAAMVRLVEQAQTQKARAQRLADHIAGVFVPVVFV 371
Query: 318 IATLIATVPPLVFKESFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKG 377
IA L A LV L +LVI+CPCAL L+ P GR A+ GI IKG
Sbjct: 372 IAGL-AGAAWLVSGAGADRAFSVTLGVLVIACPCALGLATPTAMMVASGRGAQLGIFIKG 430
Query: 378 SNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGFT----EEEILRFAALAEAHSNHP 433
L+ ++ V FDKTGTLT G V+ + T EE+L AA E+ S H
Sbjct: 431 YRALETIRSIDTVVFDKTGTLTVGQLAVSTVTMAGSGTSERDREEVLGLAAAVESASEHA 490
Query: 434 IAKAIREAYGKEINEAEITEYEEIAGHGVRARIDSVEVMVGNDKLLHRSNIEHDTCKVKG 493
+A AI A + + + +AG GV + V VG + R+ HD V
Sbjct: 491 MAAAIVAA---SPDPGPVNGFVAVAGCGVSGEVGGHHVEVGKPSWITRTTPCHDAALVSA 547
Query: 494 ---------TIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVA 544
T+ V +DG + I+D +K+ A AV L+ G+R +++TGD+R A
Sbjct: 548 RLDGESRGETVVFVSVDGVVRAALTIADTLKDSAAAAVAALRSRGLR-TILLTGDNRAAA 606
Query: 545 EEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMG 604
+ +A Q+G+D A++LPE KV +I++L +E + VGDGIND P L AD+G+A+G
Sbjct: 607 DAVAAQVGIDSAVADMLPEGKVDVIQRLREE--GHTVAMVGDGINDGPALVGADLGLAIG 664
Query: 605 ALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGLGIFGKA 664
G+D A+ AD++++ D + +P+A+ +AR T R + N+I+A G +A I + G
Sbjct: 665 R-GTDVALGAADIILVRDDLNTVPQALDLARATMRTIRMNMIWAFGYNVAAIPIAAAGLL 723
Query: 665 TMWEAVFADVGVALIAVFNAMRV 687
A A + V N++R+
Sbjct: 724 NPLIAGAAMAFSSFFVVSNSLRL 746
>pir||H69200 heavy-metal transporting CPx-type ATPase - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2621844|gb|AAB85258.1| (AE000854) heavy-metal
transporting CPx-type ATPase [Methanobacterium
thermoautotrophicum]
Length = 675
Score = 276 bits (698), Expect = 6e-73
Identities = 210/646 (32%), Positives = 339/646 (51%), Gaps = 44/646 (6%)
Query: 70 HDHAHGEFEKRTIYFIGISLVLFTIGIL----MRYYYAIDNTLVFGLFLASYLISGWKVL 125
H H ++ +R I + +++ + +G L + + + LV L A +L G+ L
Sbjct: 31 HGHHEEDYRRRFIICLLMTIPVILLGELPTGNVLFSFEGSEFLVLILSSAIFLYGGYPFL 90
Query: 126 KSAIVNSLNGNVFDENFLIAVATIGAFLIKEYPEGVAV----MLFYV----------IGE 171
+ ++ L+ LIAVA A+ Y GV + M+F+V +G
Sbjct: 91 RGSL-RELSSRTPGMMTLIAVAITVAYT---YSLGVILGLEGMVFFVELVTLIDVMLLGH 146
Query: 172 FLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGV 231
+++ ++ + +++ L L A+LV DG V V LK GDI++V+ GE+VP DG
Sbjct: 147 WIEMRSIMSASGAVERLAGLLPRRAHLVVDGKVEDVDVSTLKPGDIVVVRSGERVPSDGT 206
Query: 232 IIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVE 291
+I G S V+ S LTGES P GD ++ G IN G L V V R ES +S+I+ELV
Sbjct: 207 VIRGESHVNESLLTGESRPIKKVPGDGVIGGSINTGGSLTVEVERVGEESFISQIIELVG 266
Query: 292 NASARKAKTEKFITRFAHYYTPAVV--GIATLIATVPPLVFKESFTSWVYRALVILVISC 349
A + +T+ + A + T + G+ T IA + + F S + RA+ ++V +C
Sbjct: 267 RAQEGRTRTQVLADKAAFWLTSIALLGGLLTFIAW--SWLGMDVFFS-LERAVTLMVTAC 323
Query: 350 PCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIE 409
P AL L+IPL +A GILI+ + +D +V FDKTGTLT G +T +
Sbjct: 324 PHALGLAIPLVIAVSTAISAGRGILIRNRESFENARDPDVVVFDKTGTLTMGELGITDVI 383
Query: 410 TRNGFTEE-EILRFAALAEAHSNHPIAKAIREAYGKEINEAEITEYEEIAGHGVRARIDS 468
+ + +E EIL +AA E+ S+HPIA+ I EA + + + + + G GV ++
Sbjct: 384 SFDPEMDEGEILSYAAAVESGSSHPIARGIVEAVAEVL---PVENFNSLEGRGVMGHVNG 440
Query: 469 VEVMV---GNDKLLHRSNIEHDTCKVKG---TIAHVVIDGQYAGYIVISDEIKEDAHLAV 522
V V G + L S + ++ G T V++D + G I ++D I+ +A AV
Sbjct: 441 SVVKVLSYGYTEELGFSISDPRVDELIGQAKTTVFVIVDDELRGCIALADMIRPEAREAV 500
Query: 523 KELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLV 582
L+ GVR +M+TGDS VA +A ++G+D + AEL+P +K I KL++E ++V
Sbjct: 501 GILRSRGVR-CLMLTGDSSAVAGWVASEVGIDDYMAELIPIEKYDEIRKLQEE--GLRVV 557
Query: 583 FVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVW 642
VGDG+NDAP L +AD+GVA+GA G+D AIE+ADVV++ P + + +A T +
Sbjct: 558 MVGDGVNDAPALVQADIGVAIGA-GTDVAIESADVVLVRSNPLDVVDLMDLAAATYSKMK 616
Query: 643 ENIIFALGVKLAFIGLG---IFGKATMWEAVFADVGVALIAVFNAM 685
EN+I+A G + + L ++G+ + + ++L V A+
Sbjct: 617 ENLIWATGYNVIALPLAAGVLYGQGIILSPAMGAILMSLSTVIVAL 662
>sp|Q9X5V3|ATCU_RHILV COPPER-TRANSPORTING ATPASE >gi|4633808|gb|AAD26860.1|AF127795_2
(AF127795) copper transporter ActP [Rhizobium
leguminosarum bv. viciae]
Length = 841
Score = 275 bits (697), Expect = 8e-73
Identities = 175/509 (34%), Positives = 282/509 (55%), Gaps = 22/509 (4%)
Query: 157 YPEGVAVMLFYV-IGEFLQDMAVDKSRRSIKALLALKAEYANLV-RDGTVVKVKPEELKV 214
Y E AV++ V +G+ L+ A +++ +I+ALL L + A + +G V +++ V
Sbjct: 291 YFEAAAVIVALVFVGQVLELKARERTGSAIRALLDLAPKTARRIDAEGNESDVPVDDINV 350
Query: 215 GDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRV 274
D + V+PGE+VPVDG ++EG S+VD S ++GE +P +GD + G IN G +
Sbjct: 351 ADRLRVRPGERVPVDGSVLEGQSTVDESMISGEPLPVEKSKGDPLTGGTINKNGTFVMSA 410
Query: 275 TRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLI----ATVPPLVF 330
+ +++ +SRI+++V A +A + + R + + PAVV +A L A + P
Sbjct: 411 EKVGADTVLSRIVDMVAKAQRSRAPIQGAVDRVSAVFVPAVVAVALLAFLAWAAIGP--- 467
Query: 331 KESFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIV 390
+ + + A+ +L+I+CPCAL L+ P+ GR A EG+LIK + L+ +
Sbjct: 468 EPRMANGLLAAVAVLIIACPCALGLATPMSIMIATGRGAGEGVLIKDAEALERFSKGDTL 527
Query: 391 AFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAI-REAYGKEINEA 449
DKTGTLT+G K+T I E+ +L AA E S HP+A+AI A + +
Sbjct: 528 IVDKTGTLTEGKPKLTDIAAFGRVGEDRLLSLAASLERGSEHPLAEAIVSGAEERGVPFV 587
Query: 450 EITEYEEIAGHGVRARIDSVEVMVGNDKLLHRSNIE-----HDTCKVKG---TIAHVVID 501
E+T +E G GV+ D V +GN +L I+ T ++G T+ VV D
Sbjct: 588 EVTGFEAKTGKGVQGIADGTMVALGNSAMLADLGIDPAALSEKTEALRGDGKTVMFVVFD 647
Query: 502 GQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELL 561
G AG + ++D IK A++ L G+ K++M TGD+ A +AK LG+D A++L
Sbjct: 648 GALAGLVAVADRIKPTTAAAIQALHDSGL-KIIMATGDNERTARAVAKSLGIDEVRADVL 706
Query: 562 PEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMD 621
PE K +I++L + KG + GDG+NDAP LA ADVG+AMG G+D A+E+A + ++
Sbjct: 707 PEGKKALIDEL-RSKG-AIIAMAGDGVNDAPALAAADVGIAMGT-GADVAMESAGITLVK 763
Query: 622 DKPSKLPKAIQIARKTQRIVWENIIFALG 650
+ + +A ++A T R + +N+ FA G
Sbjct: 764 GDLTGIVRARRLAEATMRNIRQNLGFAFG 792
>gb|AAD29109.1|AF082565_1 (AF082565) ATP dependent copper transporter [Arabidopsis thaliana]
>gi|4760380|gb|AAD29115.1| (AF091112) ATP dependent
copper transporter [Arabidopsis thaliana]
>gi|6850337|gb|AAC79141.2| (AC002342) ATP dependent
copper transporter (RAN1) [Arabidopsis thaliana]
>gi|9758383|dbj|BAB08832.1| (AB016874) ATP dependent
copper transporter [Arabidopsis thaliana]
Length = 1001
Score = 275 bits (697), Expect = 8e-73
Identities = 185/603 (30%), Positives = 308/603 (50%), Gaps = 62/603 (10%)
Query: 117 YLISGWKVLKSAIVN-------SLNGNVFDENFLIAVATIGAFLIKEYPEGVAVML-FYV 168
+ ++ W+ L++ N + + F + + F Y + A+++ F +
Sbjct: 355 FYVAAWRALRNGSTNMDVLVALGTSASYFYSVGALLYGAVTGFWSPTYFDASAMLITFVL 414
Query: 169 IGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEE------LKVGDIIIVKP 222
+G++L+ +A K+ ++K L+ L A L+ +G K+ E ++ GD + V P
Sbjct: 415 LGKYLESLAKGKTSDAMKKLVQLTPATAILLTEGKGGKLVGEREIDALLIQPGDTLKVHP 474
Query: 223 GEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSEST 282
G K+P DGV++ G+S V+ S +TGES+P + + ++ G IN+ G L ++ T+ S++
Sbjct: 475 GAKIPADGVVVWGSSYVNESMVTGESVPVSKEVDSPVIGGTINMHGALHMKATKVGSDAV 534
Query: 283 VSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATL----------IATVPPLVFKE 332
+S+I+ LVE A KA +KF A + P V+ +A + P E
Sbjct: 535 LSQIISLVETAQMSKAPIQKFADYVASIFVPVVITLALFTLVGWSIGGAVGAYPDEWLPE 594
Query: 333 SFTSWVYR---ALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASI 389
+ T +V+ ++ ++VI+CPCAL L+ P G A G+LIKG + L+
Sbjct: 595 NGTHFVFSLMFSISVVVIACPCALGLATPTAVMVATGVGATNGVLIKGGDALEKAHKVKY 654
Query: 390 VAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAI----------- 438
V FDKTGTLT+G VT + + E L A AEA S HP+AKAI
Sbjct: 655 VIFDKTGTLTQGKATVTTTKVFSEMDRGEFLTLVASAEASSEHPLAKAIVAYARHFHFFD 714
Query: 439 -----REAYGKEINEA----EITEYEEIAGHGVRARIDSVEVMVGNDKLL---------H 480
E K++ + + +++ + G G++ ++ ++VGN KL+ H
Sbjct: 715 ESTEDGETNNKDLQNSGWLLDTSDFSALPGKGIQCLVNEKMILVGNRKLMSENAINIPDH 774
Query: 481 RSNIEHDTCKVKGTIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDS 540
D + T V +G+ G + I+D +K +A L V+ L R+GVR +MVTGD+
Sbjct: 775 VEKFVEDLEESGKTGVIVAYNGKLVGVMGIADPLKREAALVVEGLLRMGVRP-IMVTGDN 833
Query: 541 RDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVG 600
A +AK++G++ AE++P K +I L+K+ + VGDGIND+P LA ADVG
Sbjct: 834 WRTARAVAKEVGIEDVRAEVMPAGKADVIRSLQKD--GSTVAMVGDGINDSPALAAADVG 891
Query: 601 VAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGL-- 658
+A+GA G+D AIE AD V+M + + AI ++RKT + N +FA+ + I +
Sbjct: 892 MAIGA-GTDVAIEAADYVLMRNNLEDVITAIDLSRKTLTRIRLNYVFAMAYNVVSIPIAA 950
Query: 659 GIF 661
G+F
Sbjct: 951 GVF 953
>pir||A29576 H+/K+-exchanging ATPase (EC 3.6.1.36) - Enterococcus faecalis
Length = 583
Score = 275 bits (696), Expect = 1e-72
Identities = 177/535 (33%), Positives = 299/535 (55%), Gaps = 22/535 (4%)
Query: 159 EGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYAN-LVRDGTVVKVKPEELKVGDI 217
E +++ ++G +++ AV + +++ L L E L +DGT V +E+ GD
Sbjct: 46 ELATLIVIMLLGHWIEMNAVSNASDALQKLAELLPESVKRLKKDGTEETVSLKEVHEGDR 105
Query: 218 IIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRE 277
+IV+ G+K+P DG I +G + VD SA+TGES + GD ++ G IN G +++ VT
Sbjct: 106 LIVRAGDKMPTDGTIDKGHTIVDESAVTGESKGVKKQVGDSVIGGSINGDGTIEITVTGT 165
Query: 278 LSESTVSRILELVENASARKAKTEKFITRFAH--YYTPAVVGIATLIATVPPLVFKESFT 335
E +++E+V A K+K E + A +Y VVGI IA + F +
Sbjct: 166 -GEMVTCKVMEMVRKAQGEKSKLEFLSDKVAKWLFYVALVVGIIAFIAWL----FLANLP 220
Query: 336 SWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKT 395
+ R + + +I+CP AL L+IPL AAK G+L+K N ++ D ++ DKT
Sbjct: 221 DALERMVTVFIIACPHALGLAIPLVVARSTSIAAKNGLLLKNRNAMEQANDLDVIMLDKT 280
Query: 396 GTLTKGVFKVTKIETRN-GFTEEEILRFAALAEAHSNHPIAKAIRE-AYGKEINEAEITE 453
GTLT+G F VT IE + + EEEIL++ EAH+NHP+A I K+I + E
Sbjct: 281 GTLTQGKFTVTGIEILDEAYQEEEILKYIGALEAHANHPLAIGIMNYLKEKKITPYQAQE 340
Query: 454 YEEIAGHGVRARIDSVEVMVGNDKLLHRSNIEHDTCKVK------GTIAHVVIDGQYAGY 507
+ +AG G+ A ++ +V + N+K R ++ D ++K T++ +V+ +
Sbjct: 341 QKNLAGVGLEATVEDKDVKIINEKEAKRLGLKIDPERLKNYEAQGNTVSFLVVSDKLVAV 400
Query: 508 IVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVK 567
I + D IK +A ++ +K + VM+TGD+ A+ +A+ LG++ +Y LLP+DK
Sbjct: 401 IALGDVIKPEAKEFIQAIKEKNIIP-VMLTGDNPKAAQAVAEYLGINEYYGGLLPDDKEA 459
Query: 568 IIEK-LEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSK 626
I+++ L++ K K++ VGDGINDAP LARA +G+A+GA G+D AI++ADVV+ + P
Sbjct: 460 IVQRYLDQGK---KVIMVGDGINDAPSLARATIGMAIGA-GTDIAIDSADVVLTNSDPKD 515
Query: 627 LPKAIQIARKTQRIVWENIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIAV 681
+ +++A++T+R + +N+ + G + I L A + + VG L+++
Sbjct: 516 ILHFLELAKETRRKMIQNLWWGAGYNIIAIPLAAGILAPIGLILSPAVGAVLMSL 570
>pir||A82200 cation transport ATPase, E1-E2 family VC1437 [imported] - Vibrio
cholerae (group O1 strain N16961)
>gi|9655936|gb|AAF94594.1| (AE004222) cation transport
ATPase, E1-E2 family [Vibrio cholerae]
Length = 790
Score = 274 bits (694), Expect = 2e-72
Identities = 202/714 (28%), Positives = 353/714 (49%), Gaps = 51/714 (7%)
Query: 6 LKLEGLDCASCAYEIEEALRKE-GFKFAVVNFATKEAIIEGDIEKAKEVIKKVEPDVEVV 64
L L+G+ CA+CA+ IE+ L E G VN T A++ D + K + V + +
Sbjct: 94 LSLDGVSCAACAWLIEKQLHTEPGVVSIRVNTTTNRALLSWD--RTKTQLSHVLAQIHKL 151
Query: 65 E------EVHIHDHAHGEFEKRTIYFIGIS------LVLFTIGILMRYYYAIDNTLVFGL 112
E H+ + + K +Y +GI+ +++ + + + + +D
Sbjct: 152 GYKAAPFEADKHEAQYHDAMKTYLYRLGIAGLASMQVMMLAVALYLEAFGDLDAEFKNYF 211
Query: 113 FLASYLISGWKVLKSAIV------NSLNGNVFDENFLIAVATIGAFLI----------KE 156
S + + +L SA+ S+ G + +++A I A++ +
Sbjct: 212 RWVSLIFATPVLLYSALPFYLNAWRSIRGRTLGMDVPVSLALIFAYIASLVATITEQGEV 271
Query: 157 YPEGVAVMLFYV-IGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVG 215
+ E +++ F++ +G FL+ A K+ + LL L A + DG V VK LK G
Sbjct: 272 FFESISMFTFFLLVGRFLEMRARRKAAAASGNLLKLIPAIATTL-DGQQVPVKT--LKPG 328
Query: 216 DIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVT 275
D + V PGE +P DG II +D S LTGES+P GD + +G +N +RVT
Sbjct: 329 DCVRVLPGEHIPADGEIINNRVHIDESMLTGESLPVVKATGDHVFAGTLNGDESFDLRVT 388
Query: 276 RELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKESFT 335
++S +S I+ L ++A + K K + A Y+ ++ IA V E
Sbjct: 389 ASKADSVISNIVRLQDDAQSSKPKIAEIADIVARYFVAIILVIAAGTWFFWHQVRPED-A 447
Query: 336 SWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKT 395
W+ L +LV +CPCAL L+ P G++++ ++ + L + + DKT
Sbjct: 448 FWIM--LSVLVATCPCALSLATPTALTCATSSMGSVGVMLRKNHVFETLCKVNHLVIDKT 505
Query: 396 GTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKEINEAEITEYE 455
GTLT G +++ +ET + T+E L AA E+H+NHPIAKA R + + ++E
Sbjct: 506 GTLTHGNIEISTVETLDSLTKESCLAIAAELESHANHPIAKAFRPYKAENVT---VSEVR 562
Query: 456 EIAGHGVRARIDSVEVMVGNDKLLHRSNIEHDTCKVKGTIAHVVIDGQYAGYIVISDEIK 515
I G G+ +V +G+ + + + ++ + +DG++ D I+
Sbjct: 563 NIIGSGMEGVFAGQKVKIGSAEFVLGNPLDS-----AHNCVFLSLDGRHVATFHYRDPIR 617
Query: 516 EDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKE 575
++A +++ G+ K+ ++TGDS+ A+ +A ++ +D A+ PEDK+ + +L K
Sbjct: 618 KEAKAFIEKFHAAGI-KITLLTGDSQTNAQSVANEMQIDKVVAQAKPEDKLTYLRELNK- 675
Query: 576 KGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIAR 635
+ VGDGINDAP LA A + VAMG G+D A +AD+V++ D+ KL +A ++A
Sbjct: 676 --TDVTMMVGDGINDAPTLAGAHISVAMGG-GTDVAKASADMVLIGDRLDKLLEARELAL 732
Query: 636 KTQRIVWENIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIAVFNAMRVLR 689
KT++I+ EN+ ++LG L + L + G + AV G ++I V N++R+L+
Sbjct: 733 KTRKIIRENLAWSLGYNLLILPLAVAGLVAPYIAVVGMSGSSIIVVTNSLRLLK 786
>gb|AAG19186.1| (AE005015) molybdenum-binding protein; YvgX [Halobacterium sp.
NRC-1]
Length = 857
Score = 273 bits (691), Expect = 4e-72
Identities = 205/749 (27%), Positives = 355/749 (47%), Gaps = 98/749 (13%)
Query: 6 LKLEGLDCASCAYEIEEALRKE-GFKFAVVNFATKEAI---------------------- 42
+ + G+ CA+CA IE+A+ G NFAT +A
Sbjct: 76 IPVHGMTCANCAQTIEDAVADAPGVLDVSANFATDDAHLTYVPAAFDRDAVHAAITDAGY 135
Query: 43 --IEGDIEKAKEVIKKVEPDVEVVEEVHIHDHAHGEFEKRTIYFIGISLVLFTIGILMRY 100
I+ D + + + A G + F LF ++
Sbjct: 136 DPIDADSDTGASTQTAADEARDAERRRQRIRLAFGAVLSAPLLFFVADTFLFGGAVVPDS 195
Query: 101 YYAIDNTLVFG-----LFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIK 155
+ T+ FG L Y++ G L ++ + + + L+A+ + A++
Sbjct: 196 FTVGGLTIPFGWAEFALATPVYVVLGRSFLSNSYAALVRNGTANMDVLVALGSTTAYVYS 255
Query: 156 -------------EYPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLV-RD 201
+ +++F +G +L+ + ++ +++ LL ++A A LV D
Sbjct: 256 LASLLGVLAGGGLYFDTAALILVFITLGNYLEARSKSQASDALRELLEMEANTARLVDAD 315
Query: 202 GTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILS 261
G ++ ++++VGD + VKPGE++P DGV++ G S+VD S +TGES+P + GD+++
Sbjct: 316 GETREIPADDVEVGDRLKVKPGEQIPTDGVVVSGESAVDESMVTGESVPVSKAPGDDVVG 375
Query: 262 GMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIAT- 320
IN G+L V+ T+ +++ + +I+ V +A +R+ ++ R + Y+ PAV+ A
Sbjct: 376 ATINENGVLVVQATKVGADTAIQQIVTTVRDAQSRQPDIQRLADRISAYFVPAVIANAVF 435
Query: 321 -----------------------LIATVPPLVFKESFTSWVYRALVILVISCPCALVLSI 357
L++ P V F V+ + V+ I+CPCAL L+
Sbjct: 436 WGAVWWFAPGLLADVVSALPLWGLVSGGPAAVGTGEFAVVVFASAVL--IACPCALGLAT 493
Query: 358 PLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIE-------- 409
P G AK G+L +G + L+ + + V FDKTGTLT G ++T +E
Sbjct: 494 PAATMIGTSIGAKHGVLFQGGDVLERVTELDAVVFDKTGTLTTGAMELTDVEAVAAVPDG 553
Query: 410 ---TRN--GFTEEEILRFAALAEAHSNHPIAKAI-REAYGKEINEAEITEYEEIAGHGVR 463
TR+ E+ +LR AA AE++S HP+ AI A + ++ + +E + G G+
Sbjct: 554 GTATRSDAAVDEDAVLRLAAAAESNSEHPLGTAIVAGAEDRGLDVPAVDAFENVPGKGIV 613
Query: 464 ARIDSVEVMVGNDKLLHRSNIE-------HDTCKVKGTIAHVV-IDGQYAGYIVISDEIK 515
A +D V VGN LL ++I+ + + +G A +V +D + AG + +D +K
Sbjct: 614 ATVDGRRVRVGNRALLTSADIDPAPAADAMERLEREGKTAMLVAVDDRVAGVVADADTVK 673
Query: 516 EDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGL--DGFYAELLPEDKVKIIEKLE 573
+A V L+ G+ V M+TGD+ A +A +G+ + A +LP +K ++ +
Sbjct: 674 PEAAATVDALQDRGL-DVHMITGDNERTARAVAADVGVSPEHVRAGVLPGEKADAVDAI- 731
Query: 574 KEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQI 633
+ G+ + VGDG+NDAP LA A VG A+G+ G+D AIE ADV +M D P+ + +AI+I
Sbjct: 732 -QAGDADAMMVGDGVNDAPALATAHVGAAIGS-GTDVAIEAADVTLMRDDPADVIQAIRI 789
Query: 634 ARKTQRIVWENIIFALGVKLAFIGLGIFG 662
T + +N+ +ALG A I L G
Sbjct: 790 GEGTLAKIKQNLFWALGYNTAMIPLASLG 818
>pir||F81845 probable cation-transporting ATPase NMA1539 [imported] - Neisseria
meningitidis (group A strain Z2491)
>gi|7380180|emb|CAB84766.1| (AL162756) putative
cation-transporting ATPase [Neisseria meningitidis
Z2491]
Length = 725
Score = 273 bits (690), Expect = 6e-72
Identities = 216/731 (29%), Positives = 357/731 (48%), Gaps = 61/731 (8%)
Query: 5 KLKLEGLDCASCAYEIEEALRKEGF-KFAVVNFATKEAIIEGDIEKAK--EVIKKVEPD- 60
+ ++EG+ C +CA IE+ L K+ F + A VNFA++EA + D K ++ K +E
Sbjct: 6 RFQIEGMTCQACASRIEKVLNKKDFVESAGVNFASEEAQVVFDDSKTSVADIAKIIEKTG 65
Query: 61 ---VEVVEEVHIHDHAHGEFEKRT--IYFIGISLVLFTIGILM------RYYYAIDNTLV 109
E E+ A R + I I ++ +G+++ R+ + + L
Sbjct: 66 YGAKEKTEDTLPQPEAEHHIGWRLWLLLAINIPFLIGMVGMMLKGLNWTRHDWMLSPLLQ 125
Query: 110 FGLFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEY------------ 157
F L L KSA S+ G + + + L+ + T+ +L Y
Sbjct: 126 FALASVVQLWLAVPFYKSAWA-SIKGGLANMDVLVTIGTVSIYLYSVYMLFFSPHAAYGM 184
Query: 158 -----PEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEEL 212
G+ V+ F +G+FL+ S S+ LL L N+ RDG ++ +++
Sbjct: 185 AHVYFEVGIMVIGFVSLGKFLEHRTKKSSLNSLGLLLKLTPTQVNVQRDGEWRQLPIDQV 244
Query: 213 KVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKV 272
++GD+I GE++ DG+I G+ D S LTGES P K G ++L+G + G +
Sbjct: 245 QIGDLIRANHGERIAADGIIESGSGWADESHLTGESNPEEKKAGGKVLAGALMTEGSVVY 304
Query: 273 RVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKE 332
R + S++ + ++ + A KA + + A + PAVVGIA L+ + + K
Sbjct: 305 RAAQLGSQTLLGDMMNALSEAQGSKAPIARVADKAAAVFVPAVVGIA-LLTFIATWLIKG 363
Query: 333 SFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAF 392
+T + A+ +LVI+CPCAL L+ P G+G+A K GI K + ++ V
Sbjct: 364 DWTLALMHAVAVLVIACPCALGLATPAAIMVGMGKAVKHGIWFKDAAAMEEAAHVDAVVL 423
Query: 393 DKTGTLTKGVFKVTKI--ETRNGFTEEEILRFAALAEAHSNHPIAKAI---REAYGKEIN 447
DKTGTLT+G +V + +GF E+ + R AA E ++ HP+A+AI +A G EI
Sbjct: 424 DKTGTLTEGKPQVAAVYCVPDSGFDEDALYRIAAAVEQNAAHPLARAIVSAAQARGLEIP 483
Query: 448 EAEITEYEEIAGHGVRARIDSVE-VMVGNDKL--LHRSNIEHDTCKVKGTIAHVVIDGQY 504
A+ + I G G+ A + V G + L ++ +A V ++G+
Sbjct: 484 TAQ--NAQTIVGAGITAEVKGAGLVKAGKAEFAELTLPKFSDGVWEIASVVA-VSVNGKP 540
Query: 505 AGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPED 564
G ++D +K D A+ LK+ + V +++GD++ E +AKQLG+ + + P D
Sbjct: 541 IGAFALADALKADTAEAIGRLKKHNI-DVYIMSGDNQGTVEYVAKQLGIAHAFGNMSPRD 599
Query: 565 KVKIIEKLEKEKGNGKLV-FVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDK 623
K ++KL K GK V VGDGINDAP LA A+V AM G+D A TA +M
Sbjct: 600 KAAEVQKL---KAAGKTVAMVGDGINDAPALAAANVSFAMKG-GADVAEHTASATLMQHS 655
Query: 624 PSKLPKAIQIARKTQRIVWENIIFA-----LGVKLAFIGLGIFGKATMWEAVFADVGVAL 678
++L A+ ++R T + + +N+ FA LG+ LA +G F + A A V++
Sbjct: 656 VNQLADALSVSRATLKNIKQNLFFAFFYNILGIPLAALG---FLNPVIAGAAMAASSVSV 712
Query: 679 IAVFNAMRVLR 689
++ NA+R+ R
Sbjct: 713 LS--NALRLKR 721
>emb|CAC07984.1| (AJ278983) CopF Cu-ATPase [Ralstonia metallidurans]
Length = 751
Score = 272 bits (687), Expect = 1e-71
Identities = 193/655 (29%), Positives = 334/655 (50%), Gaps = 58/655 (8%)
Query: 45 GDIEKAKEVIKKVEPDVEVVEEVHIHDHAHGEFEKRTIYFIGISLVLFTIGI----LMRY 100
G+ K ++ + PD+E E + D F +R + + ++ V+F + + L
Sbjct: 70 GNCPKCGMALEPLLPDIEDGENPELTD-----FRRRFWWTLPLTAVVFVLAMFGSRLGLM 124
Query: 101 YYAIDNTLVFGLFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFL------- 153
+ + + F L L +GW + + + +N + + LI + T A++
Sbjct: 125 SPDMQSWMEFVLATPVVLWAGWPFFERCLQSFVNRSP-NMWTLIGLGTGAAYIYSVVATI 183
Query: 154 --------------IKEYPEGVAVML-FYVIGEFLQDMAVDKSRRSIKALLALKAEYANL 198
I Y E AV++ ++G+ L+ A ++ +IK+LL L + A
Sbjct: 184 APGVFPPAFAAHGRIGVYFEAAAVIISLTLLGQLLELKARSQTSAAIKSLLGLAPKTARR 243
Query: 199 V-RDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGD 257
+ DG V + VGD++ V+PGEKVPVDGV+ EG+SS+D S +TGE MP + + GD
Sbjct: 244 IGTDGQEEDVALNHVHVGDLLRVRPGEKVPVDGVVTEGSSSIDESMITGEPMPVSKRAGD 303
Query: 258 EILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVG 317
++ IN +G L +R + +++ +S+I+++V A KA ++ R A + AV+G
Sbjct: 304 HVIGATINTSGSLIIRSEKVGAQTMLSQIVQMVAQAQRSKAPMQRMADRVAGVFVLAVIG 363
Query: 318 IATLIATVPPLVFKESFTSW--VYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILI 375
+A L F S + + A+ +L+I+CPCAL L+ P+ G+ A G+L
Sbjct: 364 VAAATFLAWGL-FAPSRVGYLALINAVAVLIIACPCALGLATPMSIMVASGKGAANGVLF 422
Query: 376 KGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIA 435
+ + ++ L+ + + DKTGTLT+G + NG+ +EE+L AA + S HP+A
Sbjct: 423 RDAAAIENLRKVTALIVDKTGTLTEGRPAFARSVGINGYGDEEVLWLAASLDQGSEHPLA 482
Query: 436 KAIREA---YGKEINEAEITEYEEIAGHGVRARIDSVEVMVGNDKLLHRSNIEHDTCKVK 492
A+ A G + +AE +E G GVR ++ + +GN L+ ++ + + +
Sbjct: 483 AALVSAARDAGLTLEKAE--NFESSTGIGVRGKVGGERLAIGNTALMEEERVQVEPLRAQ 540
Query: 493 --------GTIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVA 544
++ ++ +DG AG + +SD IK A++ L+ G+R V+M TGD A
Sbjct: 541 AEDLRAQGASVMYLSVDGTLAGLLAVSDPIKHSTPEALQSLRDEGIR-VIMATGDGLATA 599
Query: 545 EEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMG 604
+ +A L +D F E+ P DK+ ++ +L + + GDGINDAP LA+ADVG+AMG
Sbjct: 600 KAVATNLNIDEFRGEVKPADKLALVTQL--QDAGDVVAMAGDGINDAPALAKADVGIAMG 657
Query: 605 ALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIF-----ALGVKLA 654
G+D A+ +A V ++ + +A ++ T R + +N+ F ALGV LA
Sbjct: 658 T-GTDVAMNSAQVTLVKGDLRGIARARNLSEATIRNMKQNLAFAFVYNALGVPLA 711
>pir||D81097 cation transport ATPase, E1-E2 family NMB1325 [imported] -
Neisseria meningitidis (group B strain MD58)
>gi|7226567|gb|AAF41700.1| (AE002480) cation transport
ATPase, E1-E2 family [Neisseria meningitidis MC58]
Length = 720
Score = 270 bits (684), Expect = 3e-71
Identities = 214/725 (29%), Positives = 356/725 (48%), Gaps = 54/725 (7%)
Query: 5 KLKLEGLDCASCAYEIEEALRKEGF-KFAVVNFATKEAIIEGDIEKAK--EVIKKVEPD- 60
+ ++EG+ C +CA IE+ L K+ F + A VNFA++EA + D K ++ K +E
Sbjct: 6 RFQIEGMTCQACASRIEKVLNKKDFVESAGVNFASEEAQVVFDDSKTSVADIAKIIEKTG 65
Query: 61 ---VEVVEEVHIHDHAHGEFEKRT--IYFIGISLVLFTIGILM-RYYYAIDNTLVFGLFL 114
E E+ A R ++ I + ++ G+++ R+ + I F L
Sbjct: 66 YGAKEKTEDTLPQPEAEHHIGWRLWLLFTINVPFLIGMAGMMIGRHDWMIPPLWQFALAS 125
Query: 115 ASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEY----------------- 157
L KSA S+ G + + + L+ + T+ +L Y
Sbjct: 126 VVQLWLAIPFYKSAWA-SIKGGLANMDVLVTIGTVSIYLYSVYMLFFSPHAAYGMAHVYF 184
Query: 158 PEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDI 217
GV V+ F +G+FL+ S S+ LL L N+ R+G ++ +++++GD+
Sbjct: 185 EVGVMVIGFVSLGKFLEHRTKKSSLNSLGLLLKLTPTQVNVQRNGEWKQLPIDQVQIGDL 244
Query: 218 IIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRE 277
I GE++ DG+I G+ D S LTGES P K G ++L+G + G + R T+
Sbjct: 245 IRANHGERIAADGIIESGSGWADESHLTGESNPEEKKAGGKVLAGALMTEGSVVYRATQL 304
Query: 278 LSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKESFTSW 337
S++ + ++ + A KA + + A + PAVVGIA L V L+ K +T
Sbjct: 305 GSQTQLGDMMNALSEAQGSKAPIARVADKAAAVFVPAVVGIALLTFIVTWLI-KGDWTVA 363
Query: 338 VYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGT 397
+ A+ +LVI+CPCAL L+ P G+G+A K GI K + ++ V DKTGT
Sbjct: 364 LMHAVAVLVIACPCALGLATPAAIMVGMGKAVKHGIWFKDAAAMEEAAHVDAVVLDKTGT 423
Query: 398 LTKGVFKVTKI--ETRNGFTEEEILRFAALAEAHSNHPIAKAI---REAYGKEINEAEIT 452
LT+G +V + +GF E+ + R AA E ++ HP+A+AI +A G +I A+
Sbjct: 424 LTEGSPQVAAVYCVPDSGFDEDALYRIAAAVEQNAAHPLARAIVSAAQARGLDIPAAQ-- 481
Query: 453 EYEEIAGHGVRARIDSVEVMVGNDKLLHRSNIEH--DTCKVKGTIAHVVIDGQYAGYIVI 510
+ + G G+ A ++ V ++ + D +I V +D + G +
Sbjct: 482 NAQTVVGAGITAEVEGVGLVKAGKAEFAELALPKFLDGVWDIASIVAVSVDNKPIGAFAL 541
Query: 511 SDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIE 570
+D +K D A+ LK+ + V +++GD++ E +AKQLG+ + + P DK ++
Sbjct: 542 ADALKADTAEAIGRLKKHNI-DVYIMSGDNQGTVEYVAKQLGIAHAFGNMSPRDKAAEVQ 600
Query: 571 KLEKEKGNGKLV-FVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPK 629
KL K GK V VGDGINDAP LA A+V AM G+D A TA +M ++L
Sbjct: 601 KL---KAAGKTVAMVGDGINDAPALAAANVSFAMKG-GADVAEHTASATLMQHSVNQLAD 656
Query: 630 AIQIARKTQRIVWENIIFA-----LGVKLAFIGLGIFGKATMWEAVFADVGVALIAVFNA 684
A+ +++ T + + +N+ FA LG+ LA +G F + A A V++++ NA
Sbjct: 657 ALLVSQATLKNIKQNLFFAFFYNILGIPLAALG---FLNPVIAGAAMAASSVSVLS--NA 711
Query: 685 MRVLR 689
+R+ R
Sbjct: 712 LRLKR 716
>sp|P46840|CTPB_MYCLE CATION-TRANSPORTING P-TYPE ATPASE B >gi|1076024|pir||S49521
cation-transporting P-type ATPase - Mycobacterium leprae
>gi|7436395|pir||S77653 cation-transporting ATPase (EC
3.6.1.-) ctpB, P-type - Mycobacterium leprae
>gi|559912|emb|CAA86363.1| (Z46257) cation-transporting
P-type ATPase [Mycobacterium leprae]
Length = 750
Score = 269 bits (680), Expect = 8e-71
Identities = 217/737 (29%), Positives = 353/737 (47%), Gaps = 70/737 (9%)
Query: 5 KLKLEGLDCASCAYEIEEALRKEGFKFAVVNFATKEAIIEGDIEKAKEVIKKVEPDVEVV 64
+L + G+ CA+CA +E L K A VNFAT+ A I+ ++ A + ++ +V+
Sbjct: 20 QLDVAGMLCAACASRVETKLNKIPGVRASVNFATRVATIDA-VDVAVDELR------QVI 72
Query: 65 EEVHIHDHAHGE-----------FEKRTIYFIGISLVLFTIGILMRYYYAIDNTLVF--- 110
E+ AH E + + + + ++ +LF + +AI T F
Sbjct: 73 EQAGYRATAHAESAVEEIDPDADYARNLLRRLIVAALLFVPLADLSTMFAIVPTNRFPGW 132
Query: 111 GLFLASYLI-----SGWKVLKSAIVNSLNGNVFDENFLIA--VATIG-----AFLIKE-- 156
G L + + W + A+ N+ E + A +A G F+ KE
Sbjct: 133 GYLLTALAAPIVTWAAWPFHRVALRNARYRAASMETLISAGILAATGWSLSTIFVDKEPR 192
Query: 157 ----------------YPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYAN-LV 199
+ V +F + G F + A K+ +++AL A A+ L+
Sbjct: 193 QTHGIWQAILHSDSIYFEVAAGVTVFVLAGRFFEARAKSKAGSALRALAARGAKNVEVLL 252
Query: 200 RDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEI 259
+G + + ELK +V+PGE + DGV+I+GT+++D SA+TGE+ P +
Sbjct: 253 PNGAELTIPAGELKKQQHFLVRPGETITADGVVIDGTATIDMSAITGEARPVHASPASTV 312
Query: 260 LSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIA 319
+ G L G L + T ++ + ++ LVE+A +KA+ + R A + P V IA
Sbjct: 313 VGGTTVLDGRLVIEATAVGGDTQFAAMVRLVEDAQVQKARVQHLADRIAAVFVPMVFVIA 372
Query: 320 TLIATVPPLVFKESFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSN 379
L A L+ S L +LVI+CPC L L+ P GR A+ GI IKG
Sbjct: 373 GL-AGASWLLAGASPDRAFSVVLGVLVIACPCTLGLATPTAMMVASGRGAQLGIFIKGYR 431
Query: 380 YLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIR 439
L+ + V FDKTGTLT G V+ + + G+ E+L A+ EA S H +A AI
Sbjct: 432 ALETINAIDTVVFDKTGTLTLGQLSVSTVTSTGGWCSGEVLALASAVEAASEHSVATAIV 491
Query: 440 EAYGKEINEAEITEYEEIAGHGVRARIDSVEVMVGNDKLLHRSNIEHDTC--------KV 491
AY + + ++ AG GV + V +G + R N D ++
Sbjct: 492 AAYA---DPRPVADFVAFAGCGVSGVVAEHHVKIGKPSWVTR-NAPCDVVLESARRRRRI 547
Query: 492 KG-TIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQ 550
G T+ V +DG G + I+D +K+ A A+ L G+ +++TGD++ A +A Q
Sbjct: 548 TGETVVFVSVDGVACGAVAIADTVKDSAADAISALCSRGLH-TILLTGDNQAAARAVAAQ 606
Query: 551 LGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDA 610
+G+D A++LPE KV +I++L +++G+ + VGDGIND P LA AD+G+AMG G+D
Sbjct: 607 VGIDTVIADMLPEAKVDVIQRL-RDQGH-TVAMVGDGINDGPALACADLGLAMGR-GTDV 663
Query: 611 AIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGLGIFGKATMWEAV 670
AI AD++++ D +P A+ +AR T R + N+I+A G +A I + G A
Sbjct: 664 AIGAADLILVRDSLGVVPVALDLARATMRTIRINMIWAFGYNVAAIPIASSGLLNPLIAG 723
Query: 671 FADVGVALIAVFNAMRV 687
A + V N++R+
Sbjct: 724 AAMAFSSFFVVSNSLRL 740
>gb|AAK43003.1| Copper-transporting ATPase [Sulfolobus solfataricus]
Length = 695
Score = 268 bits (679), Expect = 1e-70
Identities = 215/710 (30%), Positives = 367/710 (51%), Gaps = 60/710 (8%)
Query: 5 KLKLEGLDCASCAYEIEEALRK-EGFKFAVVNFATKEAIIEGDIEK-AKEVIKKVEPDVE 62
K + G+ CA CA IE+ L+K EG V + E ++ D + E+IKK ++E
Sbjct: 11 KFYVGGMACAFCASTIEKGLKKIEGVNEVKVVLESSEVFVKYDNSLVSSEIIKK---EIE 67
Query: 63 -----VVEEVHIHDHAHGEFEKRTIYFIGISLVLFTIGILMRYYYAIDNTLVFGLFLASY 117
V + D + +R+I ++ +L + YY I + L +
Sbjct: 68 KLGYYVSDRSLFSDELLKDSRRRSIISWSLTTLLGLL-YFFEYYNIIFRVTIILLVTTNL 126
Query: 118 LISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIK-----EYPEGVAVMLF------ 166
+ K A +++ + +E+ L VA I ++++ E+ + + LF
Sbjct: 127 FYIALPIYKGAS-HAIGKGILNEHVLYGVAGISSYILGIVGFLEFNKNLFGFLFISSLLT 185
Query: 167 --YVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIVKPGE 224
++ ++ + +K +++ ++ L+ YA+L+ V K LK GDI+IVKPGE
Sbjct: 186 SLHLSAGWMGAILNNKVEKALHKVIELRPPYAHLINGEDVPVTK---LKKGDIVIVKPGE 242
Query: 225 KVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVS 284
K+P+DGV+++G S V + +TGES P + +GD ++ G N +G LKV++T + + S +S
Sbjct: 243 KIPLDGVVVDGESEVSEAIITGESEPVSKGKGDFVIGGSTNGSGYLKVKITEDYNNSYLS 302
Query: 285 RILELVENASARKAKTEKFITR-FAHYYTP--AVVGIATLIA--TVPPLVFKESFTSWVY 339
+I+ LV + +K+ F + + P + I T+IA L+ K+ + +
Sbjct: 303 KIIGLVNYSKQKKSAILTFFDKVIDKIWVPLALAISIITVIAWGLYGILIGKDLWLYGII 362
Query: 340 RALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLT 399
L++ I+ PCA+ S P + +G++IK SN + +K+ + FDKTGTLT
Sbjct: 363 NGLLVSTIAYPCAIGFSSPSMALSLYEKMLHKGMIIKNSNVYEKIKEIDTIIFDKTGTLT 422
Query: 400 KGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKE--INEAEITEYEEI 457
G VT+ + L +AA EA S+HPIAKAI + Y KE + E+ +++EI
Sbjct: 423 YGTPIVTQF-----IGDSLSLAYAASVEALSSHPIAKAIVK-YAKEQGVKILEVKDFKEI 476
Query: 458 AGHGVRARIDSVEVMVGNDKLLHRSNIEHDTCKVKGTIAHVVIDGQYAGYIVISDEIKED 517
+G GVR +I +DK++ E++ IA V I+G+ ISD + +
Sbjct: 477 SGIGVRGKI--------SDKIIEVKKAENN-----NDIA-VYINGEPIASFNISDVPRPN 522
Query: 518 AHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKG 577
+++LK G+ K+++++GD D +E++K+L + +Y+ L PEDKV+IIEKL K+ G
Sbjct: 523 LKDYLEKLKNEGL-KIIILSGDKEDKVKELSKELNIQEYYSNLSPEDKVRIIEKL-KQNG 580
Query: 578 NGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKT 637
N K++ +GDG+NDA LA ADV VAMG G D + AD++++ + L I+ ++
Sbjct: 581 N-KVLMIGDGVNDAAALALADVSVAMGN-GVDISKNVADIILVSNDIGTLLGLIKNRKRL 638
Query: 638 QRIVWENIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIAVFNAMRV 687
+ N+I AL I L IFG TM A+ + ++L ++F RV
Sbjct: 639 SNAIPSNVILALTYNGIGIPLAIFGILTMKFAMIIMI-LSLFSIFINSRV 687
>gb|AAF19707.1|AC008047_14 (AC008047) F2K11.18 [Arabidopsis thaliana]
Length = 1191
Score = 268 bits (677), Expect = 2e-70
Identities = 202/619 (32%), Positives = 316/619 (50%), Gaps = 64/619 (10%)
Query: 91 LFTIGILMRYYYAIDNTLVFG--LFLASY--LISGWKVLKSAIVNSLNGNVFDENF-LIA 145
+ T+G ++R A V G + SY L G + I N F + ++
Sbjct: 334 MLTVGEIIRCVLATPVQFVIGWRFYTGSYKALRRGSANMDVLIALGTNAAYFYSLYTVLR 393
Query: 146 VATIGAFLIKEYPEGVAVML-FYVIGEFLQDMAVDKSRRSIKALLALKAEYANLV---RD 201
AT F ++ E A+++ F ++G++L+ MA K+ ++I L+ L + A L+ ++
Sbjct: 394 AATSPDFKGVDFFETSAMLISFIILGKYLEVMAKGKTSQAIAKLMNLAPDTAILLSLDKE 453
Query: 202 GTVV---KVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDE 258
G V ++ ++ D+I + PG KV DG +I G S V+ S +TGE+ P ++GD
Sbjct: 454 GNVTGEEEIDGRLIQKNDVIKIVPGAKVASDGYVIWGQSHVNESMITGEARPVAKRKGDT 513
Query: 259 ILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVV-- 316
++ G +N G+L V+VTR SES +++I+ LVE+A KA +K R + ++ P V+
Sbjct: 514 VIGGTLNENGVLHVKVTRVGSESALAQIVRLVESAQLAKAPVQKLADRISKFFVPLVIFL 573
Query: 317 GIATLIA-------------TVPPLVFKESFTSWVYRALVILVISCPCALVLSIPLGYFG 363
+T +A +P + +SF + + ++VI+CPCAL L+ P
Sbjct: 574 SFSTWLAWFLAGKLHWYPESWIPSSM--DSFELALQFGISVMVIACPCALGLATPTAVMV 631
Query: 364 GIGRAAKEGILIKGSNYLDALKDASIV------------AFDKTGTLTKGVFKVTKIETR 411
G G A +G+LIKG L+ S+V FDKTGTLT G V K +
Sbjct: 632 GTGVGASQGVLIKGGQALERAHKVSLVCSNLVYGFVNCIVFDKTGTLTMGKPVVVKTKLL 691
Query: 412 NGFTEEEILRFAALAEAHSNHPIAKAIREAYGKEINE-------AEITEYEEIAGHGVRA 464
E A E +S HP+AKAI E Y K+ + E ++ I G GV+A
Sbjct: 692 KNMVLREFYELVAATEVNSEHPLAKAIVE-YAKKFRDDEENPAWPEACDFVSITGKGVKA 750
Query: 465 RIDSVEVMVGNDKLL--HRSNIEHDTCKVKG-------TIAHVVIDGQYAGYIVISDEIK 515
+ E+MVGN L+ H+ I D ++ T V I+ + G + +SD +K
Sbjct: 751 TVKGREIMVGNKNLMNDHKVIIPDDAEELLADSEDMAQTGILVSINSELIGVLSVSDPLK 810
Query: 516 EDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKE 575
A A+ LK + + K +MVTGD+ A IA+++G+D AE PE K EK+++
Sbjct: 811 PSAREAISILKSMNI-KSIMVTGDNWGTANSIAREVGIDSVIAEAKPEQKA---EKVKEL 866
Query: 576 KGNGKLV-FVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIA 634
+ G +V VGDGIND+P L ADVG+A+GA G+D AIE AD+V+M + AI ++
Sbjct: 867 QAAGHVVAMVGDGINDSPALVAADVGMAIGA-GTDIAIEAADIVLMKSNLEDVITAIDLS 925
Query: 635 RKTQRIVWENIIFALGVKL 653
RKT + N ++ALG L
Sbjct: 926 RKTFSRIRLNYVWALGYNL 944
>pir||C71250 probable cation-transporting ATPase, P-type - syphilis spirochete
>gi|3323366|gb|AAC26590.1| (AE001271)
cation-transporting ATPase, P-type [Treponema pallidum]
Length = 792
Score = 266 bits (674), Expect = 4e-70
Identities = 190/586 (32%), Positives = 310/586 (52%), Gaps = 51/586 (8%)
Query: 147 ATIGAFLIKEYPEGVAVMLFYV-IGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTV- 204
A + ++ Y E A+++ V +G++L ++ ++ R++ LL +K + A ++R +V
Sbjct: 205 ALVSHYVADLYFESAAMIVTLVTVGKYLSALSKGRTSRALTQLLDIKPKTARVIRQVSVP 264
Query: 205 -----------------------VKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDT 241
+++ +++ VGD ++VK GE VPVDG+I G +++D
Sbjct: 265 RGASPSSPTTASAASAHETHEIEIEIPAQDVLVGDTVLVKAGELVPVDGIITSGQATLDE 324
Query: 242 SALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTE 301
S +TGES+P GD ++S + TG LK R R +T+++I+ LVE +A K
Sbjct: 325 SNVTGESIPVEKGRGDSVISASLVSTGFLKFRAERVGEHTTLAQIISLVEKTAASKVPVT 384
Query: 302 KFITRFAHYYTPAVVGIATLIATVPPLVFKESFTSWVYRALVILVISCPCALVLSIPLGY 361
K + + Y+ P++V + +L++ L S A+ +LVISCPC L L++P
Sbjct: 385 KLVDAVSAYFVPSIVAL-SLLSGCAWLCAGASAEFAFSIAVTVLVISCPCVLGLAVPTAL 443
Query: 362 FGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRN-GFTEEEIL 420
G+ A+ GILIK + + ++AFDKTGTLT G ++ I T + + EE+IL
Sbjct: 444 MVATGKGAQMGILIKSAQVFQQMARTKVIAFDKTGTLTLGRPTLSHIHTLHPTYNEEDIL 503
Query: 421 RFAALAEAHSNHPIAKAIR-EAYGKEINEAEITEYEEIAGHGVRARIDSVE----VMVGN 475
A E S HP+A AI A K + IT++ G G+RAR+ VMVGN
Sbjct: 504 HLAYSLEVCSGHPLAAAISVAAQRKGMTPLAITDFNSEQGLGLRARLVHTSYAKTVMVGN 563
Query: 476 DKLLHRSNIE------HDTCKVKGTIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLG 529
+++ +I+ + ++ T V D G + +SD +K + A+ L + G
Sbjct: 564 ARMMVAHSIDGMDTYLSPSHNLEETPLFVAADKNLVGVLFVSDPVKVHSSAAIGALHKRG 623
Query: 530 VRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLV-FVGDGI 588
+ + +M+TGD + VA IA + G+ AELLP DK + I L K +G +V VGDG+
Sbjct: 624 I-QTLMLTGDVKHVAHTIAARCGVKKSKAELLPHDKEREISAL---KASGMMVAMVGDGV 679
Query: 589 NDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFA 648
NDAP LA ADVG+A+GA GSD A+E+ADVV+M + + + ++ T R + +N+ +A
Sbjct: 680 NDAPALASADVGIAIGA-GSDIAVESADVVLMRNCIRDVVTLVDLSIATVRNMKQNLFWA 738
Query: 649 -----LGVKLAF-IGLGIFGKATMWEAVFADVGVALIAVF-NAMRV 687
LGV LA +G FG A + ++ ++V NA+R+
Sbjct: 739 FFYNTLGVPLAAGLGYPFFGLRLTPMLAAAAMSLSSVSVLCNALRL 784
>sp|P46839|CTPA_MYCLE CATION-TRANSPORTING P-TYPE ATPASE A >gi|1076023|pir||S49516 cation
transporting P-type ATPase - Mycobacterium leprae
>gi|7436394|pir||S77652 cation-transporting ATPase (EC
3.6.1.-) ctpA, P-type - Mycobacterium leprae
>gi|559907|emb|CAA86358.1| (Z46257) cation transporting
P-type ATPase [Mycobacterium leprae]
Length = 780
Score = 265 bits (669), Expect = 2e-69
Identities = 171/533 (32%), Positives = 278/533 (52%), Gaps = 16/533 (3%)
Query: 163 VMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVR-DGTVVKVKPEELKVGDIIIVK 221
+ +F + G++ A + ++ AL AL A+ A +++ DG+ + + EL +V+
Sbjct: 200 ITVFVLAGKYYTARAKSHASIALLALAALSAKDAAVLQPDGSEMVIPANELNEQQRFVVR 259
Query: 222 PGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSES 281
PG+ + DG++I+G+++V S +TGE+ P V G +++ G + L G L V E+
Sbjct: 260 PGQTIAADGLVIDGSATVSMSPITGEAKPVRVNPGAQVIGGTVVLNGRLIVEAAAVGDET 319
Query: 282 TVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKESFTSWVYRA 341
++ ++ LVE A + A ++ R A + P V +A L +E V A
Sbjct: 320 QLAGMVRLVEQAQQQNANAQRLADRIASVFVPCVFAVAALDRCWMA-DRRERTRPSVLGA 378
Query: 342 LVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKG 401
+ +LVI+CPCAL L+ P GR A+ GIL+KG +A + V FDKTGTLT G
Sbjct: 379 IAVLVIACPCALGLATPTAMMVASGRGAQLGILLKGHESFEATRAVDTVVFDKTGTLTTG 438
Query: 402 VFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKEINEAEITEYEEIAGHG 461
KV+ + G+ E+L+ AA E+ S H +A AI + + + + GHG
Sbjct: 439 QLKVSAVTAAPGWQANEVLQMAATVESASEHAVALAIA---ASTTHREPVANFRAVPGHG 495
Query: 462 VRARIDSVEVMVGNDK-LLHRSN-----IEHDTCKVKG-TIAHVVIDGQYAGYIVISDEI 514
V + V VG + R N +++G T V IDG+ G I ++D +
Sbjct: 496 VSGTVAERAVRVGKPSWIASRCNSTTLVTARRNAELRGETAVFVEIDGEQCGVIAVADAV 555
Query: 515 KEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEK 574
K A AV L G R ++TGD+ A +A ++G+D A++LPEDKV +IE+L +
Sbjct: 556 KASAADAVAALHDRGFR-TALLTGDNPASAAAVASRIGIDEVIADILPEDKVDVIEQL-R 613
Query: 575 EKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIA 634
++G+ + VGDGIND P LARAD+G+A+G G+D AI AD++++ D +P + +A
Sbjct: 614 DRGH-VVAMVGDGINDGPALARADLGMAIGR-GTDVAIGAADIILVRDNLDVVPITLDLA 671
Query: 635 RKTQRIVWENIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIAVFNAMRV 687
T R + N+++A G +A I + G A A + V N++R+
Sbjct: 672 AATMRTIKFNMVWAFGYNIAAIPIAAAGLLNPLVAGAAMAFSSFFVVSNSLRL 724
>dbj|BAA23769.1| (D89981) metal-transporting P-type ATPase [Arabidopsis thaliana]
Length = 949
Score = 264 bits (668), Expect = 2e-69
Identities = 189/614 (30%), Positives = 319/614 (51%), Gaps = 59/614 (9%)
Query: 94 IGILMRYYYAIDNT-LVFGLFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAF 152
+G+ + +AI +T L L + L G K++ I + L G+ + N L+ + + +F
Sbjct: 272 LGVNAPWIHAIHSTGFHVSLCLITLLGPGRKLVLDGIKSLLKGSP-NMNTLVGLGALSSF 330
Query: 153 LIKE-------------YPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLV 199
+ + E V ++ F ++G L+ A K+ + LL++ A A L+
Sbjct: 331 SVSSLAAMIPKLGWKTFFEEPVMLIAFVLLGRNLEQRAKIKATSDMTGLLSVLASKARLL 390
Query: 200 RDG----TVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKE 255
DG + V+V L VGD++++ PG++VP DGV+ G S++D S+ TGE +P T +
Sbjct: 391 LDGDLQNSTVEVPCNSLSVGDLVVILPGDRVPADGVVKSGRSTIDESSFTGEPLPVTKES 450
Query: 256 GDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAV 315
G ++ +G INL G L V V R E+ V I+ LVE A +R+A ++ + + A +T V
Sbjct: 451 GSQVAAGSINLNGTLTVEVHRSGGETAVGDIIRLVEEAQSREAPVQQLVDKVAGRFTYGV 510
Query: 316 VGIATLIAT---------VPPLVFKESFTSWVYR-ALVILVISCPCALVLSIPLGYFGGI 365
+ ++ T +P + S S + + +LV++CPCAL L+ P G
Sbjct: 511 MALSAATFTFWNLFGAHVLPSALHNGSPMSLALQLSCSVLVVACPCALGLATPTAMLVGT 570
Query: 366 GRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKI--------ETRNGFTEE 417
A+ G+L++G + L+ V FDKTGTLTKG VT++ + ++E
Sbjct: 571 SLGARRGLLLRGGDILEKFSLVDTVVFDKTGTLTKGHPVVTEVIIPENPRHNLNDTWSEV 630
Query: 418 EILRFAALAEAHSNHPIAKAI---REAYGKEINEAEITEYEEIAGHGVRARIDSVEVMVG 474
E+L AA E+++ HP+ KAI A + +AE + E G G A +++ V VG
Sbjct: 631 EVLMLAAAVESNTTHPVGKAIVKAARARNCQTMKAEDGTFTEEPGSGAVAIVNNKRVTVG 690
Query: 475 NDKLLHRSNI---------EHDTCKVKGTIAHVVIDGQYAGYIVISDEIKEDAHLAVKEL 525
+ + R EH+ ++ ++ +D A I D+++EDA V+ L
Sbjct: 691 TLEWVKRHGATGNSLLALEEHEI--NNQSVVYIGVDNTLAAVIRFEDKVREDAAQVVENL 748
Query: 526 KRLGVRKVVMVTGDSRDVAEEIAKQLGL--DGFYAELLPEDKVKIIEKLEKEKGNGKLV- 582
R G+ V M++GD R+ A +A +G+ + A + P +K I +L+K K K+V
Sbjct: 749 TRQGI-DVYMLSGDKRNAANYVASVVGINHERVIAGVKPAEKKNFINELQKNK---KIVA 804
Query: 583 FVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVW 642
VGDGINDA LA ++VGVAMG G+ AA E + VV+M ++ ++L A++++R+T + V
Sbjct: 805 MVGDGINDAAALASSNVGVAMGG-GAGAASEVSPVVLMGNRLTQLLDAMELSRQTMKTVK 863
Query: 643 ENIIFALGVKLAFI 656
+N+ +A G + I
Sbjct: 864 QNLWWAFGYNIVGI 877
>pir||T40072 P Type Copper ATPase - fission yeast (Schizosaccharomyces pombe)
>gi|3006137|emb|CAA18378.1| (AL022299) P Type Copper
ATPase [Schizosaccharomyces pombe]
Length = 904
Score = 264 bits (667), Expect = 3e-69
Identities = 179/546 (32%), Positives = 286/546 (51%), Gaps = 53/546 (9%)
Query: 163 VMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIVKP 222
++ F +G +L+ A + ++ LL+L A ++ D +++ + ++ GD+I+VKP
Sbjct: 286 LLTFVTLGRYLESKAKGSTSAALSQLLSLAPSSATIIEDNEQIEILADLIERGDLILVKP 345
Query: 223 GEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSEST 282
GE +PVDG ++EG+S VD S+++GE +P DE+LSG N G L V+ T+ ES
Sbjct: 346 GEIIPVDGTVVEGSSYVDESSVSGEPVPVHKTIDDELLSGTANGNGRLLVKATKSPRESQ 405
Query: 283 VSRILELVENASARKAKTEKFITRFAHYYTPAVVGIA----------TLIATVPPLVFKE 332
++ I++LV+ A A ++F R A + P +V ++ T ++ P VF +
Sbjct: 406 LAVIVDLVQRAQISHAPIQQFADRVAGIFVPVIVALSISTFTFWFLFTKYSSKYPSVFDD 465
Query: 333 ---SFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASI 389
F + + ++V++CPCAL LS P G G A GI+IKG L+ L
Sbjct: 466 PMGKFAVCLKLTISVVVVACPCALGLSTPTAVMVGTGVGALNGIIIKGGEILERLNQVDT 525
Query: 390 VAFDKTGTLTKGVFKVTKIETRNGFTEEEIL--------RFAALAEAHSNHPIAKAIREA 441
V FDKTGTLT G VT I + EE+L F +E+ S HPI KAI E
Sbjct: 526 VVFDKTGTLTVGKLSVTDISIVDNL--EELLDIPKNIFWAFVKASESSSEHPIGKAITEK 583
Query: 442 YGK--EINEAEITEYEEIAGHGV----RARIDSVEVMVGNDKLLHRSNI---EHDTCKVK 492
+ +++E I + + G GV R + + ++GN LL +N+ + K+K
Sbjct: 584 ASEFTDVSEIGIESFNAVPGEGVDVVLRWKERTFHALLGNSLLLEHNNVSIPDDFDSKLK 643
Query: 493 ------GTIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEE 546
T + IDGQ+ G++ D+++ D++ V LK+LG +KV ++TGD + A
Sbjct: 644 LSSSSGLTCVRIAIDGQFVGFLGCMDQVRPDSYQTVSALKQLG-KKVCLLTGDQKATARR 702
Query: 547 IAKQLGLD--GFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMG 604
+A+ L +D YAE +P K +II+KL+ +K + VGDGIND+P L ADVG+A
Sbjct: 703 VAQGLEIDFSDVYAEAVPSQKAEIIQKLKDQK--HCVAMVGDGINDSPSLVLADVGIA-P 759
Query: 605 ALGSDAAIETADV------VIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLA---F 655
GS A+E+ADV V++D S + + R +VW I + + +A F
Sbjct: 760 INGSGIALESADVILVRKGVLLDTAVSFDLSRVIVKRIKMNLVWACIYNFVMIPIAMGFF 819
Query: 656 IGLGIF 661
+ GI+
Sbjct: 820 LPWGIY 825
>gi|4502321 ATPase, Cu++ transporting, alpha polypeptide (Menkes syndrome);
ATPase, Cu++ transporting, alpha polypeptide [Homo
sapiens] >gi|179253|gb|AAA35580.1| (L06133)
Cu++-transporting P-type ATPase [Homo sapiens]
Length = 1500
Score = 263 bits (664), Expect = 6e-69
Identities = 233/846 (27%), Positives = 391/846 (45%), Gaps = 182/846 (21%)
Query: 5 KLKLEGLDCASCAYEIEEALRKE-GFKFAVVNFATKEAIIEGDIE--KAKEVIKKVEP-- 59
+L + G+ CASC ++IE +L K G + V AT +A I+ D E +++I +E
Sbjct: 567 ELVVRGMTCASCVHKIESSLTKHRGILYCSVALATNKAHIKYDPEIIGPRDIIHTIESLG 626
Query: 60 -DVEVVEEVHIHDHAHGEFEKR--------TIYFIGISLVLFTIGILMRYYYA------- 103
+ +V++ H + E R +++F + L T ++M +++A
Sbjct: 627 FEASLVKKDRSASHLDHKREIRQWRRSFLVSLFFCIPVMGLMTYMMVMDHHFATLHHNQN 686
Query: 104 ------------------------IDNTLVFGLFLASYLISGWKVLKSAIVNSLNGNVFD 139
+ N L F L + GW A +L +
Sbjct: 687 MSKEEMINLHSSMFLERQILPGLSVMNLLSFLLCVPVQFFGGWYFYIQAY-KALKHKTAN 745
Query: 140 ENFLIAVATIGAF-------LIKEYPEGVA-----------VMLFYVIGEFLQDMAVDKS 181
+ LI +AT AF L+ Y + +F +G +L+ +A K+
Sbjct: 746 MDVLIVLATTIAFAYSLIILLVAMYERAKVNPITFFDTPPMLFVFIALGRWLEHIAKGKT 805
Query: 182 RRSIKALLALKAEYANLVR-DGTVVKVKPEELKV-----GDIIIVKPGEKVPVDGVIIEG 235
++ L++L+A A +V D + + E++ V GDII V PG K PVDG +IEG
Sbjct: 806 SEALAKLISLQATEATIVTLDSDNILLSEEQVDVELVQRGDIIKVVPGGKFPVDGRVIEG 865
Query: 236 TSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASA 295
S VD S +TGE+MP K G +++G IN G L + T +++T+S+I++LVE A
Sbjct: 866 HSMVDESLITGEAMPVAKKPGSTVIAGSINQNGSLLICATHVGADTTLSQIVKLVEEAQT 925
Query: 296 RKAKTEKFITRFAHYYTPAV--VGIATLIATV--------------PPLVFKESFTSWVY 339
KA ++F + + Y+ P + V IATL+ + P S T +
Sbjct: 926 SKAPIQQFADKLSGYFVPFIVFVSIATLLVWIVIGFLNFEIVETYFPGYNRSISRTETII 985
Query: 340 R-----ALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDK 394
R ++ +L I+CPC+L L+ P G G A+ GILIKG L+ +V FDK
Sbjct: 986 RFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKVKVVVFDK 1045
Query: 395 TGTLTKG---VFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKEINEAEI 451
TGT+T G V +V + N + +IL AE++S HP+ AI + +E++ +
Sbjct: 1046 TGTITHGTPVVNQVKVLTESNRISHHKILAIVGTAESNSEHPLGTAITKYCKQELDTETL 1105
Query: 452 ---TEYEEIAGHGVRARIDSVEVMVGNDKLLHRS--NIEHDTCK------------VKGT 494
+++ + G G+ ++ ++E LLH++ NIE + K T
Sbjct: 1106 GTCIDFQVVPGCGISCKVTNIE------GLLHKNNWNIEDNNIKNASLVQIDASNEQSST 1159
Query: 495 IAHVVID-------------------------------------------GQYAGYIVIS 511
+ ++ID G+ A + +
Sbjct: 1160 SSSMIIDAQISNALNAQQHKVLIGNREWMIRNGLVINNDVNDFMTEHERKGRTAVLVAVD 1219
Query: 512 DE----------IKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELL 561
DE +K +A LA+ LK +G+ +VV++TGD+ A IA Q+G+ +AE+L
Sbjct: 1220 DELCGLIAIADTVKPEAELAIHILKSMGL-EVVLMTGDNSKTARSIASQVGITKVFAEVL 1278
Query: 562 PEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMD 621
P KV +++L++E ++ VGDGIND+P LA A+VG+A+G G+D AIE ADVV++
Sbjct: 1279 PSHKVAKVKQLQEE--GKRVAMVGDGINDSPALAMANVGIAIGT-GTDVAIEAADVVLIR 1335
Query: 622 DKPSKLPKAIQIARKTQRIVWENIIFAL-----GVKLA---FIGLGIFGKATMWEAVFAD 673
+ + +I ++RKT + + N +FAL G+ +A F+ +G+ + M A A
Sbjct: 1336 NDLLDVVASIDLSRKTVKRIRINFVFALIYNLVGIPIAAGVFMPIGLVLQPWMGSAAMAA 1395
Query: 674 VGVALI 679
V+++
Sbjct: 1396 SSVSVV 1401
>sp|Q04656|AT7A_HUMAN COPPER-TRANSPORTING ATPASE 1 (COPPER PUMP 1) (MENKES
DISEASE-ASSOCIATED PROTEIN) >gi|480034|pir||S36149
copper-transporting ATPase (EC 3.6.1.-) alpha chain -
human >gi|8546838|emb|CAB94714.1| (X82336) Menkes disease
[Homo sapiens]
Length = 1500
Score = 263 bits (664), Expect = 6e-69
Identities = 233/846 (27%), Positives = 391/846 (45%), Gaps = 182/846 (21%)
Query: 5 KLKLEGLDCASCAYEIEEALRKE-GFKFAVVNFATKEAIIEGDIE--KAKEVIKKVEP-- 59
+L + G+ CASC ++IE +L K G + V AT +A I+ D E +++I +E
Sbjct: 567 ELVVRGMTCASCVHKIESSLTKHRGILYCSVALATNKAHIKYDPEIIGPRDIIHTIESLG 626
Query: 60 -DVEVVEEVHIHDHAHGEFEKR--------TIYFIGISLVLFTIGILMRYYYA------- 103
+ +V++ H + E R +++F + L T ++M +++A
Sbjct: 627 FEASLVKKDRSASHLDHKREIRQWRRSFLVSLFFCIPVMGLMTYMMVMDHHFATLHHNQN 686
Query: 104 ------------------------IDNTLVFGLFLASYLISGWKVLKSAIVNSLNGNVFD 139
+ N L F L + GW A +L +
Sbjct: 687 MSKEEMINLHSSMFLERQILPGLSVMNLLSFLLCVPVQFFGGWYFYIQAY-KALKHKTAN 745
Query: 140 ENFLIAVATIGAF-------LIKEYPEGVA-----------VMLFYVIGEFLQDMAVDKS 181
+ LI +AT AF L+ Y + +F +G +L+ +A K+
Sbjct: 746 MDVLIVLATTIAFAYSLIILLVAMYERAKVNPITFFDTPPMLFVFIALGRWLEHIAKGKT 805
Query: 182 RRSIKALLALKAEYANLVR-DGTVVKVKPEELKV-----GDIIIVKPGEKVPVDGVIIEG 235
++ L++L+A A +V D + + E++ V GDII V PG K PVDG +IEG
Sbjct: 806 SEALAKLISLQATEATIVTLDSDNILLSEEQVDVELVQRGDIIKVVPGGKFPVDGRVIEG 865
Query: 236 TSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASA 295
S VD S +TGE+MP K G +++G IN G L + T +++T+S+I++LVE A
Sbjct: 866 HSMVDESLITGEAMPVAKKPGSTVIAGSINQNGSLLICATHVGADTTLSQIVKLVEEAQT 925
Query: 296 RKAKTEKFITRFAHYYTPAV--VGIATLIATV--------------PPLVFKESFTSWVY 339
KA ++F + + Y+ P + V IATL+ + P S T +
Sbjct: 926 SKAPIQQFADKLSGYFVPFIVFVSIATLLVWIVIGFLNFEIVETYFPGYNRSISRTETII 985
Query: 340 R-----ALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDK 394
R ++ +L I+CPC+L L+ P G G A+ GILIKG L+ +V FDK
Sbjct: 986 RFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKVKVVVFDK 1045
Query: 395 TGTLTKG---VFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKEINEAEI 451
TGT+T G V +V + N + +IL AE++S HP+ AI + +E++ +
Sbjct: 1046 TGTITHGTPVVNQVKVLTESNRISHHKILAIVGTAESNSEHPLGTAITKYCKQELDTETL 1105
Query: 452 ---TEYEEIAGHGVRARIDSVEVMVGNDKLLHRS--NIEHDTCK------------VKGT 494
+++ + G G+ ++ ++E LLH++ NIE + K T
Sbjct: 1106 GTCIDFQVVPGCGISCKVTNIE------GLLHKNNWNIEDNNIKNASLVQIDASNEQSST 1159
Query: 495 IAHVVID-------------------------------------------GQYAGYIVIS 511
+ ++ID G+ A + +
Sbjct: 1160 SSSMIIDAQISNALNAQQHKVLIGNREWMIRNGLVINNDVNDFMTEHERKGRTAVLVAVD 1219
Query: 512 DE----------IKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELL 561
DE +K +A LA+ LK +G+ +VV++TGD+ A IA Q+G+ +AE+L
Sbjct: 1220 DELCGLIAIADTVKPEAELAIHILKSMGL-EVVLMTGDNSKTARSIASQVGITKVFAEVL 1278
Query: 562 PEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMD 621
P KV +++L++E ++ VGDGIND+P LA A+VG+A+G G+D AIE ADVV++
Sbjct: 1279 PSHKVAKVKQLQEE--GKRVAMVGDGINDSPALAMANVGIAIGT-GTDVAIEAADVVLIR 1335
Query: 622 DKPSKLPKAIQIARKTQRIVWENIIFAL-----GVKLA---FIGLGIFGKATMWEAVFAD 673
+ + +I ++RKT + + N +FAL G+ +A F+ +G+ + M A A
Sbjct: 1336 NDLLDVVASIDLSRKTVKRIRINFVFALIYNLVGIPIAAGVFMPIGLVLQPWMGSAAMAA 1395
Query: 674 VGVALI 679
V+++
Sbjct: 1396 SSVSVV 1401
>emb|CAA20565.1| (AL031394) metal-transporting P-type ATPase (fragment) [Arabidopsis
thaliana]
Length = 870
Score = 262 bits (663), Expect = 8e-69
Identities = 188/614 (30%), Positives = 318/614 (51%), Gaps = 59/614 (9%)
Query: 94 IGILMRYYYAIDNT-LVFGLFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAF 152
+G+ + +AI +T L L + L G K++ I + L G+ + N L+ + + +F
Sbjct: 193 LGVNAPWIHAIHSTGFHVSLCLITLLGPGRKLVLDGIKSLLKGSP-NMNTLVGLGALSSF 251
Query: 153 LIKE-------------YPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLV 199
+ + E V ++ F ++G L+ A K+ + LL++ A L+
Sbjct: 252 SVSSLAAMIPKLGWKTFFEEPVMLIAFVLLGRNLEQRAKIKATSDMTGLLSVLPSKARLL 311
Query: 200 RDG----TVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKE 255
DG + V+V L VGD++++ PG++VP DGV+ G S++D S+ TGE +P T +
Sbjct: 312 LDGDLQNSTVEVPCNSLSVGDLVVILPGDRVPADGVVKSGRSTIDESSFTGEPLPVTKES 371
Query: 256 GDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAV 315
G ++ +G INL G L V V R E+ V I+ LVE A +R+A ++ + + A +T V
Sbjct: 372 GSQVAAGSINLNGTLTVEVHRSGGETAVGDIIRLVEEAQSREAPVQQLVDKVAGRFTYGV 431
Query: 316 VGIATLIAT---------VPPLVFKESFTSWVYR-ALVILVISCPCALVLSIPLGYFGGI 365
+ ++ T +P + S S + + +LV++CPCAL L+ P G
Sbjct: 432 MALSAATFTFWNLFGAHVLPSALHNGSPMSLALQLSCSVLVVACPCALGLATPTAMLVGT 491
Query: 366 GRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKI--------ETRNGFTEE 417
A+ G+L++G + L+ V FDKTGTLTKG VT++ + ++E
Sbjct: 492 SLGARRGLLLRGGDILEKFSLVDTVVFDKTGTLTKGHPVVTEVIIPENPRHNLNDTWSEV 551
Query: 418 EILRFAALAEAHSNHPIAKAI---REAYGKEINEAEITEYEEIAGHGVRARIDSVEVMVG 474
E+L AA E+++ HP+ KAI A + +AE + E G G A +++ V VG
Sbjct: 552 EVLMLAAAVESNTTHPVGKAIVKAARARNCQTMKAEDGTFTEEPGSGAVAIVNNKRVTVG 611
Query: 475 NDKLLHRSNI---------EHDTCKVKGTIAHVVIDGQYAGYIVISDEIKEDAHLAVKEL 525
+ + R EH+ ++ ++ +D A I D+++EDA V+ L
Sbjct: 612 TLEWVKRHGATGNSLLALEEHEI--NNQSVVYIGVDNTLAAVIRFEDKVREDAAQVVENL 669
Query: 526 KRLGVRKVVMVTGDSRDVAEEIAKQLGL--DGFYAELLPEDKVKIIEKLEKEKGNGKLV- 582
R G+ V M++GD R+ A +A +G+ + A + P +K I +L+K K K+V
Sbjct: 670 TRQGI-DVYMLSGDKRNAANYVASVVGINHERVIAGVKPAEKKNFINELQKNK---KIVA 725
Query: 583 FVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVW 642
VGDGINDA LA ++VGVAMG G+ AA E + VV+M ++ ++L A++++R+T + V
Sbjct: 726 MVGDGINDAAALASSNVGVAMGG-GAGAASEVSPVVLMGNRLTQLLDAMELSRQTMKTVK 784
Query: 643 ENIIFALGVKLAFI 656
+N+ +A G + I
Sbjct: 785 QNLWWAFGYNIVGI 798
>pir||T06003 metal-transporting ATPase, P-type (EC 3.6.1.-) - Arabidopsis
thaliana >gi|4490319|emb|CAB38810.1| (AL035678)
metal-transporting P-type ATPase [Arabidopsis thaliana]
>gi|7270300|emb|CAB80069.1| (AL161583)
metal-transporting P-type ATPase [Arabidopsis thaliana]
Length = 949
Score = 262 bits (663), Expect = 8e-69
Identities = 188/614 (30%), Positives = 318/614 (51%), Gaps = 59/614 (9%)
Query: 94 IGILMRYYYAIDNT-LVFGLFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAF 152
+G+ + +AI +T L L + L G K++ I + L G+ + N L+ + + +F
Sbjct: 272 LGVNAPWIHAIHSTGFHVSLCLITLLGPGRKLVLDGIKSLLKGSP-NMNTLVGLGALSSF 330
Query: 153 LIKE-------------YPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLV 199
+ + E V ++ F ++G L+ A K+ + LL++ A L+
Sbjct: 331 SVSSLAAMIPKLGWKTFFEEPVMLIAFVLLGRNLEQRAKIKATSDMTGLLSVLPSKARLL 390
Query: 200 RDG----TVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKE 255
DG + V+V L VGD++++ PG++VP DGV+ G S++D S+ TGE +P T +
Sbjct: 391 LDGDLQNSTVEVPCNSLSVGDLVVILPGDRVPADGVVKSGRSTIDESSFTGEPLPVTKES 450
Query: 256 GDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAV 315
G ++ +G INL G L V V R E+ V I+ LVE A +R+A ++ + + A +T V
Sbjct: 451 GSQVAAGSINLNGTLTVEVHRSGGETAVGDIIRLVEEAQSREAPVQQLVDKVAGRFTYGV 510
Query: 316 VGIATLIAT---------VPPLVFKESFTSWVYR-ALVILVISCPCALVLSIPLGYFGGI 365
+ ++ T +P + S S + + +LV++CPCAL L+ P G
Sbjct: 511 MALSAATFTFWNLFGAHVLPSALHNGSPMSLALQLSCSVLVVACPCALGLATPTAMLVGT 570
Query: 366 GRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKI--------ETRNGFTEE 417
A+ G+L++G + L+ V FDKTGTLTKG VT++ + ++E
Sbjct: 571 SLGARRGLLLRGGDILEKFSLVDTVVFDKTGTLTKGHPVVTEVIIPENPRHNLNDTWSEV 630
Query: 418 EILRFAALAEAHSNHPIAKAI---REAYGKEINEAEITEYEEIAGHGVRARIDSVEVMVG 474
E+L AA E+++ HP+ KAI A + +AE + E G G A +++ V VG
Sbjct: 631 EVLMLAAAVESNTTHPVGKAIVKAARARNCQTMKAEDGTFTEEPGSGAVAIVNNKRVTVG 690
Query: 475 NDKLLHRSNI---------EHDTCKVKGTIAHVVIDGQYAGYIVISDEIKEDAHLAVKEL 525
+ + R EH+ ++ ++ +D A I D+++EDA V+ L
Sbjct: 691 TLEWVKRHGATGNSLLALEEHEI--NNQSVVYIGVDNTLAAVIRFEDKVREDAAQVVENL 748
Query: 526 KRLGVRKVVMVTGDSRDVAEEIAKQLGL--DGFYAELLPEDKVKIIEKLEKEKGNGKLV- 582
R G+ V M++GD R+ A +A +G+ + A + P +K I +L+K K K+V
Sbjct: 749 TRQGI-DVYMLSGDKRNAANYVASVVGINHERVIAGVKPAEKKNFINELQKNK---KIVA 804
Query: 583 FVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVW 642
VGDGINDA LA ++VGVAMG G+ AA E + VV+M ++ ++L A++++R+T + V
Sbjct: 805 MVGDGINDAAALASSNVGVAMGG-GAGAASEVSPVVLMGNRLTQLLDAMELSRQTMKTVK 863
Query: 643 ENIIFALGVKLAFI 656
+N+ +A G + I
Sbjct: 864 QNLWWAFGYNIVGI 877
>gb|AAK42770.1| Cation transporting ATPase (pacS) [Sulfolobus solfataricus]
Length = 755
Score = 261 bits (661), Expect = 1e-68
Identities = 196/687 (28%), Positives = 343/687 (49%), Gaps = 78/687 (11%)
Query: 19 EIEEALRKEGFKFAVVNFATKEAI-------IEGDIEKAKEVIK------------KVEP 59
E+ +A+RK G+ A F K + IE E K V+ + P
Sbjct: 73 ELVKAVRKAGYDVATEKFTIKLNVNPEEMPKIERKFENVKGVVDVKSNPGLGIVSVEYNP 132
Query: 60 DVEVVEEVHIHDHAHGEF------EKRTIYF--------IGISLVLFTIGILMRYYYAID 105
+ EE+ GE EK +Y + + ++ + L+ +++ I
Sbjct: 133 ETTTPEEILKEAGVKGEIVNEQRSEKSILYKDFHDLLRRLAVGIIFTPLTYLLPFFFGIL 192
Query: 106 NTLVFGLFLASYLISG-WKVLKSAIVN-----SLNGNVFDENFLIAVATIGAFLIKEYPE 159
++ + G ++ LK+ N SL N+ +L ++ F Y +
Sbjct: 193 VSIAVQFYSGLRFHKGAYRALKNKTTNMDVLVSLASNIL---WLSSIFLHNTF----YAD 245
Query: 160 GVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIII 219
++ F ++G+ L+ K I+ Y ++DG VV ELKVGD++I
Sbjct: 246 ASLLITFILVGKTLEAYIKAKMSAEIRI-----EPYKATLKDGRVVN--SNELKVGDVVI 298
Query: 220 VKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELS 279
V+ GE++P DG+I G V+ + LTGE P K+GD +L+G I + G L+V VTR
Sbjct: 299 VRAGERIPADGIIENGEGEVNEAILTGEQKPVLKKKGDNVLAGGILVNGYLEVYVTRNWD 358
Query: 280 ESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKESFTSWVY 339
S + ++ E V A + + + + + + P V+ I+ L V V + S +
Sbjct: 359 RSYIVQVTESVRGAYNTRVSIQNLVDKVSSIFVPIVISISALTFLVWKFVLDYNLYSSLL 418
Query: 340 RALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLT 399
++ +L +CPCAL L+ P+ + RA K GI+I+ + + +++ ++ DKTGT+T
Sbjct: 419 FSVAVLAAACPCALGLASPMAMLVSVRRALKRGIIIRDGSIFEEMRNINVAILDKTGTVT 478
Query: 400 KGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKEINEAEITEYEEIAG 459
+G + + ++ F E L AA+AE+ S HPIAKA + + EI ++EE G
Sbjct: 479 EGEYVIV---SKKEFI-EGALNLAAIAESRSIHPIAKAFHK---MNVRAGEIEQFEEFPG 531
Query: 460 HGVRARIDSVEVMVGNDKLLHRSNIEHDTCKVKGTIAHVVIDGQYAGYIVISDEIKEDAH 519
G+ AR++ +V+VG+ + R N + + +G I + I+G G + I D++++DA
Sbjct: 532 RGIYARVNGNDVIVGSKDFV-RDNCNWNV-EDEGDI-FICINGNAGGIVNIRDKLRDDAK 588
Query: 520 LAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNG 579
+ LK G+R +++ TGDS + A+EI K+LG++ EL P+DK +++++L +E GN
Sbjct: 589 KVISYLKGRGIR-IIIATGDSSNYADEIGKELGVE-VRKELTPDDKAELVKEL-RENGN- 644
Query: 580 KLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQ- 638
K++F+GDGIND+ + AD+G+A+ + G+D A VV+ + L I + +T+
Sbjct: 645 KVMFIGDGINDSIAMREADIGIAISS-GTDLAKSAGKVVV-----NSLDDIIGLFEQTEL 698
Query: 639 --RIVWENIIFALGVKLAFIGL--GIF 661
R + EN+ +A G A I + G+F
Sbjct: 699 AVRKIKENLAWAFGYNTAIIPIAAGVF 725
>gb|AAD16009.1| (AF120492) night-specific ATPase [Rattus norvegicus]
Length = 665
Score = 259 bits (654), Expect = 9e-68
Identities = 180/570 (31%), Positives = 300/570 (52%), Gaps = 81/570 (14%)
Query: 187 ALLALKAEYANLVRDGTVVK---VKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSA 243
+L A +A L D +++ V E ++ GDII V PG K PVDG ++EG + D S
Sbjct: 2 SLQATEATVVTLGEDNLILREEQVPMELVQRGDIIKVVPGGKFPVDGKVLEGNTMADESL 61
Query: 244 LTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKF 303
+TGE+MP T K G +++G IN G + ++ T +++T+++I++LVE A KA ++
Sbjct: 62 ITGEAMPVTKKPGSIVIAGSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKAPIQQL 121
Query: 304 ITRFAHYYTPAVVGIATLIATVPPLVFKESF----------------TSWVYR-----AL 342
RF+ Y+ P ++ I+TL V ++ F T + R ++
Sbjct: 122 ADRFSGYFVPFIIIISTLTLVVWIIIGFVDFGIVQKYFPSPSKHISQTEVIIRFAFQTSI 181
Query: 343 VILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGV 402
+L I+CPC+L L+ P G G AA+ G+LIKG L+ V FDKTGT+T GV
Sbjct: 182 TVLCIACPCSLGLATPTAVMVGTGVAAQNGVLIKGGKPLEMAHKIKTVMFDKTGTITHGV 241
Query: 403 FKVTK---IETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKEINEAEI---TEYEE 456
+V + + + ++L AEA S HP+ A+ + +E+ + T+++
Sbjct: 242 PRVMRFLLLVDVATLSLRKVLAVVGTAEASSEHPLGVAVTKYCKEELGTETLGYSTDFQA 301
Query: 457 IAGHGVRARIDSVE------------------------------VMVGNDKLLHRSNIEH 486
+ G G+ ++ +VE V++GN + + R+ +
Sbjct: 302 VPGCGISCKVSNVESILAHRGPTAHPIGVGNPPIGEGTGPQTFSVLIGNREWMRRNGLTI 361
Query: 487 DTC--------KVKGTIAHVV-IDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVT 537
+ ++KG A +V IDG G I I+D +K +A LA+ LK +GV V ++T
Sbjct: 362 SSDISDAMTDHEMKGQTAILVAIDGVLCGMIAIADAVKPEAALAIYTLKSMGV-DVALIT 420
Query: 538 GDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARA 597
GD+R A IA Q+G++ +AE+LP KV +++L+ KG K+ VGDG+ND+P LA+A
Sbjct: 421 GDNRKTARAIATQVGINKVFAEVLPSHKVAKVQELQN-KGK-KVAMVGDGVNDSPALAQA 478
Query: 598 DVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFAL-----GVK 652
DVG+A+G G+D AIE ADVV++ + + +I ++++T R + N++ AL G+
Sbjct: 479 DVGIAIGT-GTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIRVNLVLALIYNMVGIP 537
Query: 653 LA---FIGLGIFGKATMWEAVFADVGVALI 679
+A F+ +GI + M A A V+++
Sbjct: 538 IAAGVFMPIGIVLQPWMGSAAMAASSVSVV 567
>gi|6320475 Cu(2+)-transporting ATPase; Ccc2p [Saccharomyces cerevisiae]
>gi|728935|sp|P38995|ATU2_YEAST PROBABLE
COPPER-TRANSPORTING ATPASE (CU2+-ATPASE)
>gi|1362274|pir||S55353 probable copper-transporting
ATPase (EC 3.6.1.-) - yeast (Saccharomyces cerevisiae)
>gi|538515|gb|AAC37425.1| (L36317) Cu++-transporting
P-type ATPase [Saccharomyces cerevisiae]
>gi|1230642|gb|AAB64451.1| (U51030) Ccc2p: Probable
Copper-transporting ATPase (Swiss Prot. accession number
P38995). [Saccharomyces cerevisiae]
Length = 1004
Score = 257 bits (650), Expect = 3e-67
Identities = 164/575 (28%), Positives = 301/575 (51%), Gaps = 46/575 (8%)
Query: 157 YPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRD---GTVVKVKPEELK 213
+ + ++ + IG++L+ +A ++ ++ L+ L +++ D ++ E L+
Sbjct: 373 FDTSIMIISYISIGKYLETLAKSQTSTALSKLIQLTPSVCSIISDVERNETKEIPIELLQ 432
Query: 214 VGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVR 273
V DI+ +KPG K+P DG+I G S +D S +TGES+ K G +++G +N G R
Sbjct: 433 VNDIVEIKPGMKIPADGIITRGESEIDESLMTGESILVPKKTGFPVIAGSVNGPGHFYFR 492
Query: 274 VTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATL----------IA 323
T E+ ++ I+++++ A KA + + A + P ++ +A L I+
Sbjct: 493 TTTVGEETKLANIIKVMKEAQLSKAPIQGYADYLASIFVPGILILAVLTFFIWCFILNIS 552
Query: 324 TVPPLVF-----KESFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGS 378
PP+ F ++F + A +++++CPCAL L+ P G G A+ G+LIKG
Sbjct: 553 ANPPVAFTANTKADNFFICLQTATSVVIVACPCALGLATPTAIMVGTGVGAQNGVLIKGG 612
Query: 379 NYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGFT----EEEILRFAALAEAHSNHPI 434
L+ + FDKTGTLT G V K + + E+E+L E+ S+HP+
Sbjct: 613 EVLEKFNSITTFVFDKTGTLTTGFMVVKKFLKDSNWVGNVDEDEVLACIKATESISDHPV 672
Query: 435 AKA-IREAYGKEINE---AEITEYEEIAGHGVRARI----DSVEVMVGNDKL-----LHR 481
+KA IR G N+ A + E E + G G+ ++ ++ ++ +GN+ L L +
Sbjct: 673 SKAIIRYCDGLNCNKALNAVVLESEYVLGKGIVSKCQVNGNTYDICIGNEALILEDALKK 732
Query: 482 SNIEHDTCKVKGTIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSR 541
S + T+++V ++G G I+DE+K D++ V+ L+R G + M+TGD+
Sbjct: 733 SGFINSNVDQGNTVSYVSVNGHVFGLFEINDEVKHDSYATVQYLQRNGY-ETYMITGDNN 791
Query: 542 DVAEEIAKQLGL--DGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADV 599
A+ +A+++G+ + Y+++ P K +++K++ ++GN K+ VGDGINDAP LA +D+
Sbjct: 792 SAAKRVAREVGISFENVYSDVSPTGKCDLVKKIQDKEGNNKVAVVGDGINDAPALALSDL 851
Query: 600 GVAMGALGSDAAIETADVVIM------DDKPSKLPKAIQIARKTQRIVWENIIFALGVKL 653
G+A+ + G++ AIE AD+VI+ + L AI I+ KT + + N+ +AL +
Sbjct: 852 GIAI-STGTEIAIEAADIVILCGNDLNTNSLRGLANAIDISLKTFKRIKLNLFWALCYNI 910
Query: 654 AFIGLGIFGKATMWEAVFADVGVALIAVFNAMRVL 688
I + + G W + L F+++ V+
Sbjct: 911 FMIPIAM-GVLIPWGITLPPMLAGLAMAFSSVSVV 944
>emb|CAB08162.2| (Z94801) Menkes Disease (ATP7A) [Homo sapiens]
Length = 1376
Score = 257 bits (650), Expect = 3e-67
Identities = 223/808 (27%), Positives = 375/808 (45%), Gaps = 174/808 (21%)
Query: 5 KLKLEGLDCASCAYEIEEALRKE-GFKFAVVNFATKEAIIEGDIE--KAKEVIKKVEP-- 59
+L + G+ CASC ++IE +L K G + V AT +A I+ D E +++I +E
Sbjct: 567 ELVVRGMTCASCVHKIESSLTKHRGILYCSVALATNKAHIKYDPEIIGPRDIIHTIEGLG 626
Query: 60 -DVEVVEEVHIHDHAHGEFEKR--------TIYFIGISLVLFTIGILMRYYYA------- 103
+ +V++ H + E R +++F + L ++M +++A
Sbjct: 627 FEASLVKKDRSASHLDHKREIRQWRRSFLVSLFFCIPVMGLMIYMMVMDHHFATLHHNQN 686
Query: 104 ------------------------IDNTLVFGLFLASYLISGWKVLKSAIVNSLNGNVFD 139
+ N L F L + + GW A +L +
Sbjct: 687 MSKEEMINLHSSMFLERQILPGLSVMNLLSFLLCVPVQVFGGWYFYIQAY-KALKHKTAN 745
Query: 140 ENFLIAVATIGAF-------LIKEYPEGVA-----------VMLFYVIGEFLQDMAVDKS 181
+ LI +AT AF L+ Y + +F +G +L+ +A K+
Sbjct: 746 MDVLIVLATTIAFAYSLIILLVAMYERAKVNPITFFDTPPMLFVFIALGRWLEHIAKGKT 805
Query: 182 RRSIKALLALKAEYANLVR-DGTVVKVKPEELKV-----GDIIIVKPGEKVPVDGVIIEG 235
++ L++L+A A +V D + ++ E++ V GDII V PG K PVDG +IEG
Sbjct: 806 SEALAKLISLQATEATIVTLDSDNILLREEQVDVELVQRGDIIKVVPGGKFPVDGRVIEG 865
Query: 236 TSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASA 295
S VD S +TGE+MP K G +++G IN G L + T +++T+S+I++LVE A
Sbjct: 866 HSMVDESLITGEAMPVAKKPGSTVIAGSINQNGSLLICATHVGADTTLSQIVKLVEEAQT 925
Query: 296 RKAKTEKFITRFAHYYTPAV--VGIATLIATV--------------PPLVFKESFTSWVY 339
KA ++F + + Y+ P + V IATL+ + P S T +
Sbjct: 926 SKAPIQQFADKLSGYFVPFIVFVSIATLLVWIVIGFLNFEIVETYFPGYNRSISRTETII 985
Query: 340 R-----ALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDK 394
R ++ +L I+CPC+L L+ P G G A+ GILIKG L+ +V FDK
Sbjct: 986 RFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKVKVVVFDK 1045
Query: 395 TGTLTKG---VFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKEINEAEI 451
TGT+T G V +V + N + +IL AE++S HP+ AI + +E++ +
Sbjct: 1046 TGTITHGTPVVNQVKVLTESNRISHHKILAIVGTAESNSEHPLGTAITKYCKQELDTETL 1105
Query: 452 ---TEYEEIAGHGVRARIDSVEVMVGNDKLLHRS--NIEHDTCK------------VKGT 494
+++ + G G+ ++ ++E LLH++ NIE + K T
Sbjct: 1106 GTCIDFQVVPGCGISCKVTNIE------GLLHKNNWNIEDNNIKNASLVQIDASNEQSST 1159
Query: 495 IAHVVIDGQYA---------------------GYIVISD--------------------- 512
+ ++ID Q + G ++ +D
Sbjct: 1160 SSSMIIDAQISSALNAQQYKVLIGNREWMIRNGLVINNDVNDFMTEHERKGRTAVLVAVD 1219
Query: 513 -----------EIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELL 561
+K +A LA+ LK +G+ +VV++TGD+ A IA Q+G+ +AE+L
Sbjct: 1220 GELCGLIAIADTVKPEAELAIHILKSMGL-EVVLMTGDNSKTARSIASQVGITKVFAEVL 1278
Query: 562 PEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMD 621
P KV +++L++E ++ VGDGIND+P LA A+VG+A+G G+D AIE ADVV++
Sbjct: 1279 PSHKVAKVKQLQEE--GKRVAMVGDGINDSPALAMANVGIAIGT-GTDVAIEAADVVLIR 1335
Query: 622 DKPSKLPKAIQIARKTQRIVWENIIFAL 649
D + +I ++R+T + + N +FAL
Sbjct: 1336 DDLLDVVASIDLSRETVKRIRINFVFAL 1363
>sp|Q9ZM69|COPA_HELPJ COPPER-TRANSPORTING ATPASE >gi|7436385|pir||A71941
copper-transporting p-type ATPase - Helicobacter pylori
(strain J99) >gi|4154885|gb|AAD05935.1| (AE001471)
COPPER-TRANSPORTING P-TYPE ATPASE [Helicobacter pylori
J99]
Length = 745
Score = 256 bits (648), Expect = 5e-67
Identities = 208/744 (27%), Positives = 366/744 (48%), Gaps = 80/744 (10%)
Query: 2 MPRKLKLEGLDCASCAYEIEEALRKEGF-KFAVVNFATKEAIIEGDIEKAKEVIKKVEPD 60
M +EG+ C +C+ IE +L ++ F K V+ K A IE + + ++
Sbjct: 1 MKESFYIEGMTCTACSSGIERSLGRKSFVKKIEVSLLNKSANIEFNENETN-----LDEI 55
Query: 61 VEVVEEVHIHDHAHGEFEKRTIYFIGISLVLFTIGILMRYYYAIDNTLVFGLFLAS---- 116
+++E++ EK+ + + L L I L Y ++ L L S
Sbjct: 56 FKLIEKLGYSPKKTLAEEKKEFFSPNVKLALAVIFTLFVVYLSMGAMLSPSLLPESLLTI 115
Query: 117 -----YLISGWKVLKSAIVNSLNGNVFDENF------------LIAVATIGAFLIK---- 155
+L + +++ + IV L + + + F LIA+ T A +
Sbjct: 116 NHHSNFLNACLQLIGALIVMHLGRDFYIQGFKALWHRQPNMSSLIAIGTSAALISSLWQL 175
Query: 156 ----------------EYPEGVAVMLFYV-IGEFLQDMAVDKSRRSIKALLALKAEYANL 198
Y E V V+L +V +G+ +++++ DK+ +++AL+ + A
Sbjct: 176 YLVYTNHYTDQWSYGHYYFESVCVILMFVMVGKRIENVSKDKALDAMQALMKNAPKTALK 235
Query: 199 VRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDE 258
+ + ++V + + VGDI+ V PG + VDG IIEG +D S L+GE++P K GD+
Sbjct: 236 MHNNQQIEVLVDSIVVGDILKVLPGSAIAVDGEIIEGEGELDESMLSGEALPVYKKVGDK 295
Query: 259 ILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGI 318
+ SG +N ++ T++ ST+S+I+E++ NA + KA+ + + + + P+V+ I
Sbjct: 296 VFSGTLNSNTSFLMKATQDNKNSTLSQIIEMIHNAQSSKAEISRLADKVSSVFVPSVIAI 355
Query: 319 ATLIATVPPLVFKESFTSWVYRALV-----ILVISCPCALVLSIPLGYFGGIGRAAKEGI 373
A L V ++ + W +R + +LVISCPCAL L+ P+ +A+ G+
Sbjct: 356 AVLAFVVWLIIAPKPDFWWNFRTALEVFVSVLVISCPCALGLATPMSILVANQKASSLGL 415
Query: 374 LIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHP 433
K + L+ + + + FDKTGTLT G V I + E+L A+ E S H
Sbjct: 416 FFKDAKSLEKARLVNTIVFDKTGTLTNGKPVVKSIHSNIELL--ELLSLASSIEKSSEHV 473
Query: 434 IAKAIREAYGKEINE--AEITEYEEIAGHGVRARID----SVEVMVGNDKLLHRSNIEHD 487
IAK I E Y KE N +I+E + G G+ A++D + VGN + + N
Sbjct: 474 IAKGIVE-YAKERNAPLKDISEVKVKTGFGISAKVDYQGAKEIIKVGNSEFFNPIN---- 528
Query: 488 TCKVKGTIAHVVI-------DGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDS 540
T ++K V + + + G V+ D K+ + ++K LG+ +++GD+
Sbjct: 529 TLEIKENGILVFVGRAINEKEDELLGAFVLEDLPKKGVKEHIAQIKNLGI-NTFLLSGDN 587
Query: 541 RDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVG 600
R+ ++ A +LG+DG+ + P+DK+ I++L KEKG ++ VGDG+NDAP LA +DV
Sbjct: 588 RENVKKCALELGIDGYISNAKPQDKLNKIKEL-KEKGR-IVMMVGDGLNDAPSLAMSDVA 645
Query: 601 VAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGL-- 658
V M A GSD +++ AD+V ++ + AI++++ T + + EN+ +A FI L
Sbjct: 646 VVM-AKGSDVSVQAADIVSFNNDIKSVYSAIKLSQATIKNIKENLFWAFCYNSVFIPLAC 704
Query: 659 GIFGKAT-MWEAVFADVGVALIAV 681
G+ KA M A + ++L +V
Sbjct: 705 GVLYKANIMLSPAIAGLAMSLSSV 728
>gb|AAA96010.1| (U27382) Menkes disease gene [Homo sapiens]
Length = 1447
Score = 256 bits (647), Expect = 6e-67
Identities = 231/846 (27%), Positives = 389/846 (45%), Gaps = 182/846 (21%)
Query: 5 KLKLEGLDCASCAYEIEEALRKE-GFKFAVVNFATKEAIIEGDIE--KAKEVIKKVEP-- 59
+L + G+ CASC ++IE +L K G + V AT +A I+ D E +++I +E
Sbjct: 567 ELVVRGMTCASCVHKIESSLTKHRGILYCSVALATNKAHIKYDPEIIGPRDIIHTIESLG 626
Query: 60 -DVEVVEEVHIHDHAHGEFEKR--------TIYFIGISLVLFTIGILMRYYYA------- 103
+ +V++ H + E R +++F + L ++M +++A
Sbjct: 627 FEASLVKKDRSASHLDHKREIRQWRRSFLVSLFFCIPVMGLMIYMMVMDHHFATLHHNQN 686
Query: 104 ------------------------IDNTLVFGLFLASYLISGWKVLKSAIVNSLNGNVFD 139
+ N L F L + GW A +L +
Sbjct: 687 MSKEEMINLHSSMFLERQILPGLSVMNLLSFLLCVPVQFFGGWYFYIQAY-KALKHKTAN 745
Query: 140 ENFLIAVATIGAF-------LIKEYPEGVA-----------VMLFYVIGEFLQDMAVDKS 181
+ LI +AT AF L+ Y + +F +G +L+ +A K+
Sbjct: 746 MDVLIVLATTIAFXYSLIILLVAMYERAKVNPITFFDTPPMLFVFIALGRWLEHIAKGKT 805
Query: 182 RRSIKALLALKAEYANLVR-DGTVVKVKPEELKV-----GDIIIVKPGEKVPVDGVIIEG 235
++ L++L+A A +V D + + E++ V GDII V PG K PVDG +IEG
Sbjct: 806 SEALAKLISLQATEATIVTLDSDNILLSEEQVDVELVQRGDIIKVVPGGKFPVDGRVIEG 865
Query: 236 TSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASA 295
S VD S +TGE+MP K G +++G IN G L + T +++T+S+I++LVE A
Sbjct: 866 HSMVDESLITGEAMPVAKKPGSTVIAGSINQNGSLLICATHVGADTTLSQIVKLVEEAQT 925
Query: 296 RKAKTEKFITRFAHYYTPAV--VGIATLIATV--------------PPLVFKESFTSWVY 339
KA ++F + + Y+ P + V IATL+ + P S T +
Sbjct: 926 SKAPIQQFADKLSGYFVPFIVFVSIATLLVWIVIGFLNFEIVETYFPGYNRSISRTETII 985
Query: 340 R-----ALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDK 394
R ++ +L I+CP +L L+ P G G A+ GILIKG L+ +V FDK
Sbjct: 986 RFAFQASITVLCIACPXSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKVKVVVFDK 1045
Query: 395 TGTLTKG---VFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKEINEAEI 451
TGT+T G V +V + N + +IL AE++S HP+ AI + +E++ +
Sbjct: 1046 TGTITHGTPVVNQVKVLTESNRISHHKILAIVGTAESNSEHPLGTAITKYCKQELDTETL 1105
Query: 452 ---TEYEEIAGHGVRARIDSVEVMVGNDKLLHRS--NIEHDTCK------------VKGT 494
+++ + G G+ ++ ++E LLH++ NIE + K T
Sbjct: 1106 GTCIDFQVVPGCGISCKVTNIE------GLLHKNNWNIEDNNIKNASLVQIDASNEQSST 1159
Query: 495 IAHVVID-------------------------------------------GQYAGYIVIS 511
+ ++ID G+ A + +
Sbjct: 1160 SSSMIIDAQISNALNAQQHKVLIGNREWMIRNGLVINNDVNDFMTEHERKGRTAVLVAVD 1219
Query: 512 DE----------IKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELL 561
DE +K +A LA+ LK +G+ +VV++TGD+ A IA Q+G+ +AE+L
Sbjct: 1220 DELCGLIAIADTVKPEAELAIHILKSMGL-EVVLMTGDNSKTARSIASQVGITKVFAEVL 1278
Query: 562 PEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMD 621
P KV +++L++E ++ VGDGIND+P LA A+VG+A+G G+D AIE ADVV++
Sbjct: 1279 PSHKVAKVKQLQEE--GKRVAMVGDGINDSPALAMANVGIAIGT-GTDVAIEAADVVLIR 1335
Query: 622 DKPSKLPKAIQIARKTQRIVWENIIFAL-----GVKLA---FIGLGIFGKATMWEAVFAD 673
+ + +I ++RKT + + N +FAL G+ +A F+ +G+ + M A A
Sbjct: 1336 NDLLDVVASIDLSRKTVKRIRINFVFALIYNLVGIPIAAGVFMPIGLVLQPWMGSAAMAA 1395
Query: 674 VGVALI 679
V+++
Sbjct: 1396 SSVSVV 1401
>pir||JC2464 probable copper-transporting ATPase (EC 3.6.1.-) HRA-1 -
Enterobacteriaceae spp >gi|643613|gb|AAA62113.1|
(U16658) histidine rich P type ATPase [Escherichia coli]
Length = 731
Score = 254 bits (642), Expect = 2e-66
Identities = 192/635 (30%), Positives = 329/635 (51%), Gaps = 42/635 (6%)
Query: 68 HIHDHAHGEFEKRTIYFI--GISLVLFT--IGILMRYYYAIDNTLVFGLFLASYL-ISGW 122
H H H HG F+ + + GI+++L T +GI + + V LA+ L I G
Sbjct: 87 HAHHH-HGSFKDIFLKSLPLGIAILLITPLMGIQLPFQIIFPYADVVAAVLATILYIFGG 145
Query: 123 KVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEYP----------------EGVAVMLF 166
K + N V LI + ++ Y E ++L
Sbjct: 146 KPFLMGAKDEFNSKVPGMMSLITLGITVSYAYSVYAVAARYVTGEPVMDFFFEFTTLILI 205
Query: 167 YVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKP-EELKVGDIIIVKPGEK 225
++G +++ A+ ++ + KAL L + A++V + ++ +P +L+VGD+I V+ GE
Sbjct: 206 MLLGHWIEMKALGEAGNAQKALAELVPKDAHVVLEDDSIETRPVADLQVGDLIRVQAGEN 265
Query: 226 VPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSR 285
VP DG I G S V+ + +TGES P GDE++ G N G+L V + + +S +S+
Sbjct: 266 VPADGTIQRGESRVNEALVTGESKPIEKNPGDEVIGGSTNGDGVLYVEIKQTGDKSFISQ 325
Query: 286 ILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKESFTSWVYRALVIL 345
+ L+ A ++ ++ E + A + V IA LIA V +V + T+ ++ + L
Sbjct: 326 VQTLISQAQSQPSRAENLAQKVAGWLFYIAV-IAALIALVIWMVIADVPTAVIF-TVTTL 383
Query: 346 VISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKV 405
VI+CP AL L+IPL A G+L+K + L+ +A ++ DKTGTLT G FKV
Sbjct: 384 VIACPHALGLAIPLVTARSTSLGASRGLLVKDRDALELTTNADVMVLDKTGTLTTGEFKV 443
Query: 406 TKIETRNG-FTEEEILRFAALAEAHSNHPIAKA-IREAYGKEINEAEITEYEEIAGHGVR 463
+E N +T++EI+ + E S+HPIA++ I A + I + ++G GV
Sbjct: 444 LDVELFNDKYTKDEIVALLSGIEGGSSHPIAQSIISYAEQQGIRPVSFDSIDVMSGAGVE 503
Query: 464 ARIDSVEVMVGNDKLLHRSNIEHDTCKVKGTIAHVVIDGQYAGYIVISDEIKEDAHLAVK 523
+ + + + K R N++ D K TI+ +V + + G + + DE+K + ++
Sbjct: 504 GQANGHRYQLISQKAYGR-NLDMDIPK-GATISVLVENDEAIGAVALGDELKPTSKDLIQ 561
Query: 524 ELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVF 583
LK+ ++ +M TGD+ A+ A+ LG+D + A P+DK +++EKL+ E K++
Sbjct: 562 ALKKNKIQP-IMATGDNEKAAQGAAEILGID-YLANQSPQDKYELVEKLKAE--GKKVIM 617
Query: 584 VGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWE 643
VGDG+NDAP LA ADVG+A+GA G+ A+++AD+++ P + I++A+KT R + E
Sbjct: 618 VGDGVNDAPSLALADVGIAIGA-GTQVALDSADIILTQYSPGDIASFIELAQKTTRKMKE 676
Query: 644 NIIFALGVKLAFIGLGIFGKATMWEAVFADVGVAL 678
N+++ G FI + I + A +G+ L
Sbjct: 677 NLVWGAGYN--FIAIPIAA------GILAPIGITL 703
>emb|CAB16773.1| (Z99707) Cu2+-transporting ATPase-like protein [Arabidopsis
thaliana] >gi|7270710|emb|CAB80393.1| (AL161591)
Cu2+-transporting ATPase-like protein [Arabidopsis
thaliana]
Length = 819
Score = 252 bits (637), Expect = 9e-66
Identities = 176/628 (28%), Positives = 298/628 (47%), Gaps = 56/628 (8%)
Query: 114 LASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEYPEGVAVMLFYVIGEFL 173
+ + + G A+++ G V + + L+A+A + + EG ++ + +
Sbjct: 160 IVGFPLVGVSASLDALMDIAGGKV-NIHVLMALAAFASVFMGNALEGGLLLAMFNLAHIA 218
Query: 174 QDMAVDKSRRSIKALLALKAEYANLVR----------DGTVVKVKPEELKVGDIIIVKPG 223
++ +S +K L + A L+ D + V ++VG ++V G
Sbjct: 219 EEFFTSRSMVDVKELKESNPDSALLIEVHNGNVPNISDLSYKSVPVHSVEVGSYVLVGTG 278
Query: 224 EKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTV 283
E VPVD + +G++++ LTGE P K GD + G NL G + V+ T+ ++ST+
Sbjct: 279 EIVPVDCEVYQGSATITIEHLTGEVKPLEAKAGDRVPGGARNLDGRMIVKATKAWNDSTL 338
Query: 284 SRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKESFTSW------ 337
++I++L E A + K K ++++ F Y+ VV ++ IA + P +FK F S
Sbjct: 339 NKIVQLTEEAHSNKPKLQRWLDEFGENYSKVVVVLSLAIAFLGPFLFKWPFLSTAACRGS 398
Query: 338 VYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGT 397
VYRAL ++V + PCAL ++ PL Y I A++GIL+KG+ LDAL +AFDKTGT
Sbjct: 399 VYRALGLMVAASPCALAVA-PLAYATAISSCARKGILLKGAQVLDALASCHTIAFDKTGT 457
Query: 398 LTKGVFKVTKIETRNGF---------------TEEEILRFAALAEAHSNHPIAKAIRE-A 441
LT G IE G E+E L AA E + HPI +A+ + +
Sbjct: 458 LTTGGLTCKAIEPIYGHQGGTNSSVITCCIPNCEKEALAVAAAMEKGTTHPIGRAVVDHS 517
Query: 442 YGKEINEAEITEYEEIAGHGVRARIDSVEVMVGNDKLLHRS-----------NIEHDTCK 490
GK++ + +E G G+ A ++ V+ + +L S E ++ +
Sbjct: 518 VGKDLPSIFVESFEYFPGRGLTATVNGVKTVAEESRLRKASLGSIEFITSLFKSEDESKQ 577
Query: 491 VKGTI---------AHVVID-GQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDS 540
+K + H + Q I + D+ + + ELK +V+M+TGD
Sbjct: 578 IKDAVNASSYGKDFVHAALSVDQKVTLIHLEDQPRPGVSGVIAELKSWARLRVMMLTGDH 637
Query: 541 RDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVG 600
A +A +G+ Y L PEDK+ ++ + +E G G L+ VG+GINDAP LA A VG
Sbjct: 638 DSSAWRVANAVGITEVYCNLKPEDKLNHVKNIAREAGGG-LIMVGEGINDAPALAAATVG 696
Query: 601 VAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGLGI 660
+ + S AI AD++++ D + +P + +R+T +V +N+ AL +
Sbjct: 697 IVLAQRASATAIAVADILLLRDNITGVPFCVAKSRQTTSLVKQNVALALTSIFLAALPSV 756
Query: 661 FGKATMWEAVFADVGVALIAVFNAMRVL 688
G +W V G L+ N++R L
Sbjct: 757 LGFVPLWLTVLLHEGGTLLVCLNSVRGL 784
>sp|Q59467|COA2_HELPY COPPER-TRANSPORTING ATPASE >gi|1477772|gb|AAB05475.1| (U59625) CopA
[Helicobacter pylori]
Length = 741
Score = 252 bits (636), Expect = 1e-65
Identities = 205/736 (27%), Positives = 363/736 (48%), Gaps = 68/736 (9%)
Query: 2 MPRKLKLEGLDCASCAYEIEEALRKEGF-KFAVVNFATKEAIIEGDIEKAKEVIKKVEPD 60
M +EG+ C +C+ IE +L ++ F K V+ K A IE + + ++
Sbjct: 1 MKESFYIEGMTCTACSSGIERSLGRKSFVKKIEVSLLNKSANIEFNENETN-----LDEI 55
Query: 61 VEVVEEVHIHDHAHGEFEKRTIYFIGISLVLFTIGILMRYYYAIDNTLVFGLFLAS---- 116
+++E++ EK+ + + L L I L Y ++ L L S
Sbjct: 56 FKLIEKLGYSPKKTLAEEKKEFFSPNVKLALAVIFTLFVVYLSMGAMLSPSLLPESLLTI 115
Query: 117 -----YLISGWKVLKSAIVNSLNGNVFDENF------------LIAVATIGAFLIK---- 155
+L + +++ + IV L + + + F LIA+ T A +
Sbjct: 116 NNHSNFLNACLQLIGTLIVMHLGRDFYIQGFKALWHRQPNMSSLIAIGTSAALISSLWQL 175
Query: 156 ------------EYPEGVAVMLFYV-IGEFLQDMAVDKSRRSIKALLALKAEYANLVRDG 202
Y E V V+L +V +G+ +++++ DK+ +++AL+ + A + +
Sbjct: 176 YFVYTSQWSYGHYYFESVCVILMFVMVGKRIENVSKDKALDAMQALMKNAPKTALKMHNN 235
Query: 203 TVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSG 262
++V + + VGDI+ V PG + VDG IIEG +D S L+GE++P K GD++ SG
Sbjct: 236 QQIEVLVDSIVVGDILKVLPGSAIAVDGEIIEGEGELDESMLSGEALPVYKKVGDKVFSG 295
Query: 263 MINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLI 322
N ++ T++ ST+S+I+E++ NA + KA+ + + + + P+V+ IA L
Sbjct: 296 TFNSHTSFLMKATQDNKNSTLSQIVEMIHNAQSSKAEISRLADKVSSVFVPSVIAIAILA 355
Query: 323 ATVPPLVFKESFTSWVYRALV-----ILVISCPCALVLSIPLGYFGGIGRAAKEGILIKG 377
V ++ + W + + +LVISCPCAL L+ P+ +A+ G+ K
Sbjct: 356 FVVWLIIAPKPDFWWNFGIALEVFVSVLVISCPCALGLATPMSILVANQKASSLGLFFKD 415
Query: 378 SNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKA 437
+ L+ + + + FDKTGTLT G V + + E+L A E S H IAK
Sbjct: 416 AKSLEKARLVNTIVFDKTGTLTNGKPVVKSVHSNIELL--ELLSLAGSIEKSSEHVIAKG 473
Query: 438 IREAYGKEINE--AEITEYEEIAGHGVRARID----SVEVMVGNDKLLHRSN-IEHDTCK 490
I E Y KE N E++E + G G+ A+ D + VGN + + N +E
Sbjct: 474 IVE-YAKEHNAPLKEMSEVKVKTGFGISAKTDYQGAKEVIKVGNSEFFNPINALEIQENG 532
Query: 491 VKGTIAHVVI--DGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIA 548
+ + V+ + + G V+ D K+ + ++K+LG+ +++GD+R+ ++ A
Sbjct: 533 ILVFVGRVISEKEDELLGAFVLEDLPKKGVKEHIAQIKKLGI-NTFLLSGDNRENVKKCA 591
Query: 549 KQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGS 608
+LG+DG+ + P+DK+ I++L KEKG ++ VGDG+NDAP LA +DV V M A GS
Sbjct: 592 LELGIDGYISNAKPQDKLNKIKEL-KEKGQ-IVMMVGDGLNDAPSLAMSDVAVVM-AKGS 648
Query: 609 DAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGL--GIFGKAT- 665
D +++ AD+V ++ + AI++++ T + + EN+ +A FI L G+ KA
Sbjct: 649 DVSVQAADIVSFNNDIKSVYSAIKLSQATIKNIKENLFWAFCYNSVFIPLACGVLYKANI 708
Query: 666 MWEAVFADVGVALIAV 681
M A + ++L +V
Sbjct: 709 MLSPAIAGLAMSLSSV 724
>sp|O33533|FIXI_RHILV NITROGEN FIXATION PROTEIN FIXI (E1-E2 TYPE CATION ATPASE FIXI)
>gi|2398784|emb|CAA04807.1| (AJ001522) FixI protein
[Rhizobium leguminosarum]
Length = 761
Score = 251 bits (635), Expect = 2e-65
Identities = 173/536 (32%), Positives = 277/536 (51%), Gaps = 20/536 (3%)
Query: 157 YPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVR-DGTVVKVKPEELKVG 215
+ V+++ F +IG L + +K+R +I L L A L+ DG+ + EE+ G
Sbjct: 217 FDASVSLLFFLLIGRTLDHIMREKARAAINGLARLAPRGALLINPDGSRRYIAVEEIAAG 276
Query: 216 DIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVT 275
D I + GE+VPVDG+++ G S +D S +TGES P TV E+ SG +NLTG L +R T
Sbjct: 277 DEISIAAGERVPVDGIVVSGESDLDLSIVTGESSPVTVASDSEVSSGAMNLTGSLVLRAT 336
Query: 276 RELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKESFT 335
R S +S I+ L+E A +A+ + R A Y+P V L+A V L +
Sbjct: 337 RIAKNSLLSEIIGLMEAAEGGRARYRRIADRAATLYSPVV----HLLALVSFLAWGFLGG 392
Query: 336 SWVYRALV---ILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAF 392
W LV +L+I+CPCAL L++P+ G ++GI++K + L+ L + VAF
Sbjct: 393 DWKQAMLVAVAVLIITCPCALGLAVPVVQVVAAGELFRKGIMVKDGSALERLAETDTVAF 452
Query: 393 DKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKA-IREAYGKEINEAEI 451
DKTGTLT G ++ +++ +E A AHS HP+++A +R+ I+ +
Sbjct: 453 DKTGTLTMGSSRLVRVDA----MDESAAAIARGLAAHSRHPLSRALVRDTETAPISFDRV 508
Query: 452 TEYEEIAGHGVRARIDSVEVMVGNDKLLHRSNIEHDTCKVKGTIAHVVIDGQYAGYIVIS 511
T EI G G+ AR + +GN ++ T + + +G
Sbjct: 509 T---EIPGGGLEARNGADIYRLGNAAFACGTSFVPRTADSPFSEVVLSKNGVDLARFFFD 565
Query: 512 DEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEK 571
D ++ A A+ L G+ + ++V+GD + V + A LG+D L P+ KV+ ++
Sbjct: 566 DTLRPGACEAIDRLDAAGL-ETLIVSGDRQTVVDNTAHALGIDRALGSLTPKQKVEECQR 624
Query: 572 LEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAI 631
L E +++ VGDGINDAP LA A V +A A SD + AD+V D+ +P+AI
Sbjct: 625 LNGE--GRRVLMVGDGINDAPALAAAHVSMA-PATASDIGRQAADLVFFIDRLDAVPEAI 681
Query: 632 QIARKTQRIVWENIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIAVFNAMRV 687
+AR++ ++ +N A+G + + + I G AT A A ++I V NA+R+
Sbjct: 682 AVARRSASLIRQNFALAIGYNVLAVPIAIAGLATPLIAAVAMSTSSIIVVTNALRL 737
>pir||E81320 probable cation-transporting ATPase Cj1155c [imported] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6968588|emb|CAB73409.1| (AL139077) putative
cation-transporting ATPase [Campylobacter jejuni]
Length = 785
Score = 250 bits (633), Expect = 3e-65
Identities = 195/717 (27%), Positives = 357/717 (49%), Gaps = 50/717 (6%)
Query: 6 LKLEGLDCASCAYEIEEALRK-EGFKFAVVNFATKEAIIEGDIEKAKEVIKKVEPDVEVV 64
L + G++CA+C + E+ L K EG +N +A I D E++ +++ + +
Sbjct: 82 LMIHGIECAACVWLNEKILTKQEGILELDINHLNHKARIVFD-EQSISLVQILRLIESIG 140
Query: 65 EEVHIHDHAHG----EFEKRTIY---FIGISLVLFTIGILMRYYYAI--------DNTLV 109
+ +D + + KR Y + I+ V+ + I + Y + L
Sbjct: 141 YKASAYDASKASKKADLLKREFYSKLVVAIACVMNIMWIAVAKYAGFFSGMDKDTKDILN 200
Query: 110 FGLFL----------ASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKE--- 156
F F+ + + S +K LK +N ++ V L V ++ A +
Sbjct: 201 FAEFILCSPVLFYTGSHFYKSAFKTLKMHSLN-MDVLVISGASLAYVYSLWAMFFRVGEV 259
Query: 157 YPEGVAVMLFYV-IGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVG 215
Y + VA+++ +V IG++L+ + ++ +I L + V + +++ +G
Sbjct: 260 YFDSVAMIICFVFIGKYLEMFSKKRALDTIDGLNDFLQNEVLVFNGKEFVSKEVQKVCLG 319
Query: 216 DIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVT 275
D I++K G+K+ +DG+ G SVDTS+L GE+ P+ +++ DEI S I L G ++ T
Sbjct: 320 DRILLKTGDKILIDGICKSGEMSVDTSSLNGENTPKLIQKEDEIFSACIVLDGSVEYEAT 379
Query: 276 RELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKESFT 335
+ +S +S+I++L+E AS++KAK E + Y++ V+ IA + +ESF
Sbjct: 380 KFYKDSKLSQIIQLLELASSKKAKLESLVNSLLAYFSRTVLLIAFICFAFWFFYKEESFE 439
Query: 336 SWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKT 395
+ A+ +L+I+CPCAL L+ P+ +GRA K+ IL K S+ ++ L V FDKT
Sbjct: 440 ISLVNAIAVLIIACPCALALATPVSNLVALGRALKKHILFKSSSVIEDLSKCDCVVFDKT 499
Query: 396 GTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKEINEAEITEYE 455
G LTK ++ ++ E+ F L++ + I +++ K++N + ++
Sbjct: 500 GILTKIELELKEVFLDKALDLNELYNFVKLSKHPISQNIVLYLKQKGAKDLN-LDFKKHS 558
Query: 456 EIAGHGVRARIDSVEVMVGNDKLLHRSNI---EHDTCKVKGTIAHVVI--DGQYAGYIVI 510
I G+ A ++ ++ G+ K L I E D H + +G+ +
Sbjct: 559 SIQAKGLSAELNEGLLLGGSSKFLQEKGIVAKEFDN-------THFIFAKEGKILAFFEF 611
Query: 511 SDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIE 570
++E A + LK+ +++++++GD + E+IAK+L + + A LPEDK+K IE
Sbjct: 612 DSVLREGAKELIAYLKK-EKKELMILSGDHQKAVEKIAKKLEIQNYQASCLPEDKMKTIE 670
Query: 571 KLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKA 630
L K N K++FVGDG+NDA L A V + + GSD AIE++DV+++ + L KA
Sbjct: 671 NLSK---NYKVLFVGDGVNDALALKYASVSMTLRE-GSDLAIESSDVLLLKNDLLSLKKA 726
Query: 631 IQIARKTQRIVWENIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIAVFNAMRV 687
I++++ T +I+ +N+ F+L I L G A + ++I V NA+R+
Sbjct: 727 IKLSKNTFKIIKQNLAFSLFYNACTIPLAFLGMINPLFAAISMSFSSIIVVLNALRI 783
>pir||D81129 cation transport ATPase, E1-E2 family NMB1042 [imported] -
Neisseria meningitidis (group B strain MD58)
>gi|7226281|gb|AAF41440.1| (AE002454) cation transport
ATPase, E1-E2 family [Neisseria meningitidis MC58]
Length = 823
Score = 249 bits (629), Expect = 8e-65
Identities = 195/727 (26%), Positives = 355/727 (48%), Gaps = 58/727 (7%)
Query: 6 LKLEGLDCASCAYEIEEAL-RKEGFKFAVVNFATKEAIIEGDIEKAK--EVIKKVEPDVE 62
L L G+ CA+C + IE+ L R +G +N++T + D K + +++ K+
Sbjct: 95 LMLGGITCAACVWLIEQQLLRTDGIVRIDLNYSTHRCRVVWDDGKIRLSDILLKIRQIGY 154
Query: 63 VVEEVHIHDHAHGEFEKRTIYFIGISLVLFTIGILMRYYYAIDNTLVFGLFLASYL-ISG 121
++R Y + +++ +G++ +A+ L G +L I
Sbjct: 155 TAAPYDAQKIEAANQKERKQYIVRLAVA--GLGMMQTMMFALPTYLYGGDIEPDFLQILH 212
Query: 122 WK--------VLKSAI------VNSLNGNVFDENFLIAVATIGAFLIKEYP--------- 158
W V A+ + L + I VA I F+ Y
Sbjct: 213 WGGFLMVLPVVFYCAVPFYQGALRDLKNRRVGMDTPITVAIIMTFIAGVYSLATNAGQGM 272
Query: 159 --EGVAVMLFYVIG-EFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPE----E 211
E +A++LF+++G F++ +A K+ + + L+ L + + + D + E +
Sbjct: 273 YFESIAMLLFFLLGGRFMEHIARRKAGDAAERLVKLIPAFCHHMPDYPDTQETCEAAVVK 332
Query: 212 LKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLK 271
LK GDI++VKPGE +PVDG ++EG+S+V+ S LTGES+P +++ +G +N L
Sbjct: 333 LKAGDIVLVKPGETIPVDGTVLEGSSAVNESMLTGESLPVAKMPSEKVTAGTLNTQSPLI 392
Query: 272 VRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLV-- 329
+R R + +S I+ L++ A A+K +T + ++A + L+ VP +
Sbjct: 393 IRTDRTGGGTRLSHIVRLLDRALAQKPRTAELAEQYASSFI-----FGELLLAVPVFIGW 447
Query: 330 --FKESFTS-WVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKD 386
+ ++ T+ W+ + +LVI+CPCAL L+ P G A+EGILI G ++ L
Sbjct: 448 TLYADAHTALWI--TVALLVITCPCALSLATPTALAASTGTLAREGILIGGKQAIETLAQ 505
Query: 387 ASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKEI 446
+ + FDKTGTLT+G V +I G E +L A E S HP+A+AI +
Sbjct: 506 TTDIIFDKTGTLTQGKPAVRRISLLRGTDEAFVLAVAQALEQQSEHPLARAILNCRISDG 565
Query: 447 NEAEITEYEEI--AGHGVRARI----DSVEVMVGNDKLLHRSNIEHDTCKVKGTIAHVVI 500
+ +I + + G GV A++ ++ +G + + + + G+ ++
Sbjct: 566 SVPDIAIKQRLNRIGEGVGAQLTVNGETQVWALGRASYVAEISGKEPQTEGGGSAVYLGS 625
Query: 501 DGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAEL 560
+ ++D +K+ A AV++L + + +++GD E A+ LG+ + A+
Sbjct: 626 QSGFQAVFYLTDPLKDSAAEAVRQLAGKNL-TLHILSGDRETAVAETARALGVAHYRAQA 684
Query: 561 LPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIM 620
+PEDK++ ++ L+KE K++ +GDGINDAPVLA+ADV A A G+D A + AD+V++
Sbjct: 685 MPEDKLEYVKALQKE--GKKVLMIGDGINDAPVLAQADVSAA-AAGGTDIARDGADIVLL 741
Query: 621 DDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIA 680
++ + + AR+T+ I+ +N+I+A + + L + G W A +L
Sbjct: 742 NEDLRTVAHLLDQARRTRHIIRQNLIWAGAYNIIAVPLAVLGYVQPWIAALGMSFSSLAV 801
Query: 681 VFNAMRV 687
+ NA+R+
Sbjct: 802 LGNALRL 808
>emb|CAB90352.1| (AJ400906) putative metal ATPase [Arabidopsis thaliana]
Length = 819
Score = 249 bits (629), Expect = 8e-65
Identities = 175/628 (27%), Positives = 297/628 (46%), Gaps = 56/628 (8%)
Query: 114 LASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEYPEGVAVMLFYVIGEFL 173
+ + + G A+++ G V + + L+A+A + + EG ++ + +
Sbjct: 160 IVGFPLVGVSASLDALMDIAGGKV-NIHVLMALAAFASVFMGNALEGGLLLAMFNLAHIA 218
Query: 174 QDMAVDKSRRSIKALLALKAEYANLVR----------DGTVVKVKPEELKVGDIIIVKPG 223
++ +S +K L + A L+ D + V ++VG ++V G
Sbjct: 219 EEFFTSRSMVDVKELKESNPDSALLIEVHNGNVPNISDLSYKSVPVHSVEVGSYVLVGTG 278
Query: 224 EKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTV 283
E VPVD + +G++++ LTGE P K GD + G NL G + V+ T+ ++ST+
Sbjct: 279 EIVPVDCEVYQGSATITIEHLTGEVKPLEAKAGDRVPGGARNLDGRMIVKATKAWNDSTL 338
Query: 284 SRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKESFTSW------ 337
++I++L E A + K K ++++ F Y+ VV ++ IA + P +FK F S
Sbjct: 339 NKIVQLTEEAHSNKPKLQRWLDEFGENYSKVVVVLSLAIAFLGPFLFKWPFLSTAACRGS 398
Query: 338 VYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGT 397
VYRAL ++V + PCAL ++ PL Y I A++GIL+KG+ LDAL +AFDKTGT
Sbjct: 399 VYRALGLMVAASPCALAVA-PLAYATAISSCARKGILLKGAQVLDALASCHTIAFDKTGT 457
Query: 398 LTKGVFKVTKIETRNGF---------------TEEEILRFAALAEAHSNHPIAKAIRE-A 441
LT G IE G E+E L AA E + HPI +A+ + +
Sbjct: 458 LTTGGLTCKAIEPIYGHQGGTNSSVITCCIPNCEKEALAVAAAMEKGTTHPIGRAVVDHS 517
Query: 442 YGKEINEAEITEYEEIAGHGVRARIDSVEVMVGNDKLLHRS-----------NIEHDTCK 490
GK++ + +E G G+ A ++ V+ + +L S E ++ +
Sbjct: 518 VGKDLPSIFVESFEYFPGRGLTATVNGVKTVAEESRLRKASLGSIEFITSLFKSEDESKQ 577
Query: 491 VKGTI---------AHVVID-GQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDS 540
+K + H + Q I + D+ + + ELK +V+M+TGD
Sbjct: 578 IKDAVNASSYGKDFVHAALSVDQKVTLIHLEDQPRPGVSGVIAELKSWARLRVMMLTGDH 637
Query: 541 RDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVG 600
A +A +G+ Y L EDK+ ++ + +E G G L+ VG+GINDAP LA A VG
Sbjct: 638 DSSAWRVANAVGITEVYCNLKSEDKLNHVKNIAREAGGG-LIMVGEGINDAPALAAATVG 696
Query: 601 VAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGLGI 660
+ + S AI AD++++ D + +P + +R+T +V +N+ AL +
Sbjct: 697 IVLAQRASATAIAVADILLLRDNITGVPFCVAKSRQTTSLVKQNVALALTSIFLAALPSV 756
Query: 661 FGKATMWEAVFADVGVALIAVFNAMRVL 688
G +W V G L+ N++R L
Sbjct: 757 LGFVPLWLTVLLHEGGTLLVCLNSVRGL 784
>pir||C81835 probable P-type cation-transporting ATPase NMA1444 [imported] -
Neisseria meningitidis (group A strain Z2491)
>gi|7380097|emb|CAB84680.1| (AL162756) putative P-type
cation-transporting ATPase [Neisseria meningitidis
Z2491]
Length = 823
Score = 249 bits (628), Expect = 1e-64
Identities = 195/727 (26%), Positives = 354/727 (47%), Gaps = 58/727 (7%)
Query: 6 LKLEGLDCASCAYEIEEAL-RKEGFKFAVVNFATKEAIIEGDIEKAK--EVIKKVEPDVE 62
L L G+ CA+C + IE+ L R +G +N++T + D K + +++ K+
Sbjct: 95 LMLGGITCAACVWLIEQQLLRTDGIVRIDLNYSTHRCRVVWDDGKIRLSDILLKIRQIGY 154
Query: 63 VVEEVHIHDHAHGEFEKRTIYFIGISLVLFTIGILMRYYYAIDNTLVFGLFLASYL-ISG 121
++R Y + +++ +G++ +A+ L G +L I
Sbjct: 155 TAAPYDAQKIEAANQKERKQYIVRLAVA--GLGMMQTMMFALPTYLYGGDIEPDFLQILH 212
Query: 122 WK--------VLKSAI------VNSLNGNVFDENFLIAVATIGAFLIKEYP--------- 158
W V A+ + L + I VA I F+ Y
Sbjct: 213 WGGFLMVLPVVFYCAVPFYQGALRDLKNRRVGMDTPITVAIIMTFIAGVYSLATNAGQGM 272
Query: 159 --EGVAVMLFYVIG-EFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPE----E 211
E +A++LF+++G F++ +A K+ + + L+ L + + + D + E +
Sbjct: 273 YFESIAMLLFFLLGGRFMEHIARRKAGDAAERLVKLIPAFCHHMPDYPDTQETCEAAVVK 332
Query: 212 LKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLK 271
LK GDI++VKPGE +PVDG ++EG+S+V+ S LTGES+P +++ +G +N L
Sbjct: 333 LKAGDIVLVKPGETIPVDGTVLEGSSAVNESMLTGESLPVAKMPSEKVTAGTLNTQSPLI 392
Query: 272 VRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLV-- 329
+R R + +S I+ L++ A A+K +T + ++A + L+ VP +
Sbjct: 393 IRTDRTGGGTRLSHIVRLLDRALAQKPRTAELAEQYASSFI-----FGELLLAVPVFIGW 447
Query: 330 --FKESFTS-WVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKD 386
+ ++ T+ W+ + +LVI+CPCAL L+ P G A+EGILI G ++ L
Sbjct: 448 TLYADAHTALWI--TVALLVITCPCALSLATPTALAASTGTLAREGILIGGKQAIETLAQ 505
Query: 387 ASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKEI 446
+ + FDKTGTLT+G V +I G E +L A E S HP+A+AI +
Sbjct: 506 TTDIIFDKTGTLTQGKPAVRRISLLRGTDEAFVLAVAQALEQQSEHPLARAILNCRISDG 565
Query: 447 NEAEITEYEEI--AGHGVRARI----DSVEVMVGNDKLLHRSNIEHDTCKVKGTIAHVVI 500
+ +I + + G GV A++ ++ +G + + + + G+ ++
Sbjct: 566 SVPDIAIKQRLNRIGEGVGAQLTVNGETQVWALGRASYVAEISGKEPQTEGGGSAVYLGS 625
Query: 501 DGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAEL 560
+ + D +K+ A AV++L + + +++GD E A+ LG+ + A+
Sbjct: 626 QSGFQAVFYLQDPLKDSAAEAVRQLAGKNL-TLHILSGDRETAVAETARALGVAHYRAQA 684
Query: 561 LPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIM 620
+PEDK++ ++ L+KE K++ +GDGINDAPVLA+ADV A A G+D A + AD+V++
Sbjct: 685 MPEDKLEYVKALQKE--GKKVLMIGDGINDAPVLAQADVSAA-AAGGTDIARDGADIVLL 741
Query: 621 DDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIA 680
++ + + AR+T+ I+ +N+I+A + + L + G W A +L
Sbjct: 742 NEDLRTVAHLLDQARRTRHIIRQNLIWAGAYNIIAVPLAVLGYVQPWIAALGMSFSSLAV 801
Query: 681 VFNAMRV 687
+ NA+R+
Sbjct: 802 LGNALRL 808
>sp|O08462|COA3_HELPY COPPER-TRANSPORTING ATPASE >gi|2199521|gb|AAB66380.1| (U97567)
copper transporter ATPase [Helicobacter pylori]
Length = 745
Score = 248 bits (626), Expect = 2e-64
Identities = 205/744 (27%), Positives = 363/744 (48%), Gaps = 80/744 (10%)
Query: 2 MPRKLKLEGLDCASCAYEIEEALRKEGF-KFAVVNFATKEAIIEGDIEKAKEVIKKVEPD 60
M +EG+ C +C+ IE +L ++ F K V+ K A IE + + ++
Sbjct: 1 MKESFYIEGMTCTACSSGIERSLGRKSFVKKIEVSLLNKSANIEFNENETN-----LDEI 55
Query: 61 VEVVEEVHIHDHAHGEFEKRTIYFIGISLVLFTIGILMRYYYAIDNTLVFGLFLAS---- 116
+++E++ EK+ + + L L I L Y ++ L L S
Sbjct: 56 FKLIEKLGYSPKKTLAEEKKEFFSPNVKLALAVIFTLFVVYLSMGAMLSPSLLPESLLAI 115
Query: 117 -----YLISGWKVLKSAIVNSLNGNVFDENF------------LIAVATIGAFLIK---- 155
+L + +++ + IV L + + + F LIA+ T A +
Sbjct: 116 NNHSNFLNACLQLIGALIVMHLGRDFYIQGFKALWHRQPNMSSLIAIGTSAALISSLWQL 175
Query: 156 ----------------EYPEGVAVMLFYV-IGEFLQDMAVDKSRRSIKALLALKAEYANL 198
Y E V V+L +V +G+ +++++ DK+ +++AL+ + A
Sbjct: 176 YLVYTNHYTDQWSYGHYYFESVCVILMFVMVGKRIENVSKDKALDAMQALMKNAPKTALK 235
Query: 199 VRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDE 258
+++ ++V + + VGDI+ V PG + VDG IIEG +D S L+GE++P K GD+
Sbjct: 236 MQNNQQIEVLVDSIVVGDILKVLPGSAIAVDGEIIEGEGELDESMLSGEALPVYKKVGDK 295
Query: 259 ILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGI 318
+ SG +N ++ T+ ST+S+I+E++ NA + KA+ + + + + P+V+ I
Sbjct: 296 VFSGTLNSHTSFLMKATQNNKNSTLSQIIEMIHNAQSSKAEISRLADKVSSVFVPSVIAI 355
Query: 319 ATLIATVPPLVFKESFTSWVYRALV-----ILVISCPCALVLSIPLGYFGGIGRAAKEGI 373
A L V ++ + W + + +LVISCPCAL L+ P+ +A+ G+
Sbjct: 356 AILAFVVWLIIAPKPDFWWNFGIALEVFVSVLVISCPCALGLATPMSILVANQKASSLGL 415
Query: 374 LIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHP 433
K + L+ + + + FDKTGTLT G V + ++ E+L A E S H
Sbjct: 416 FFKDAKSLEKARLVNTIVFDKTGTLTNGKPVVKSVHSKIELL--ELLSLAGSIEKSSEHV 473
Query: 434 IAKAIREAYGKEINE--AEITEYEEIAGHGVRARID----SVEVMVGNDKLLHRSNIEHD 487
IAK I E Y KE N E++E + G G+ A+ D + VGN + + N
Sbjct: 474 IAKGIVE-YAKERNAPLKEMSEVKVKTGFGISAKTDYQGIKEIIKVGNSEFFNPIN---- 528
Query: 488 TCKVKGTIAHVVI-------DGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDS 540
T ++K V + + + G V+ D K+ + ++K LG+ +++GD+
Sbjct: 529 TLEIKENGILVFVGRAISEKEDELLGVFVLEDLPKKGVKEHIAQIKNLGI-NTFLLSGDN 587
Query: 541 RDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVG 600
R+ ++ A +LG+DG+ + P+DK+ I++L KE+G ++ VGDG+NDAP LA DV
Sbjct: 588 RENVKKCALELGIDGYISNAKPQDKLNKIKEL-KEQGQ-IVMMVGDGLNDAPSLAMNDVA 645
Query: 601 VAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGL-- 658
V M A GSD +++ AD+V ++ + AI++++ T + + EN+ +A FI L
Sbjct: 646 VVM-AKGSDVSVQAADIVSFNNDIKSVYSAIKLSQATIKNIKENLFWAFCYNSVFIPLAC 704
Query: 659 GIFGKAT-MWEAVFADVGVALIAV 681
G+ KA M A + ++L +V
Sbjct: 705 GVLYKANIMLSPAIAGLAMSLSSV 728
>pir||D72491 probable heavy-metal transporting ATPase APE2571 - Aeropyrum pernix
(strain K1) >gi|5106277|dbj|BAA81588.1| (AP000064) 621aa
long hypothetical heavy-metal transporting ATPase
[Aeropyrum pernix]
Length = 621
Score = 248 bits (626), Expect = 2e-64
Identities = 190/636 (29%), Positives = 315/636 (48%), Gaps = 48/636 (7%)
Query: 62 EVVEEVHIHDHAHGEFEKRTIYFIGISLVLFTIGILMRYYYAIDNTLVFGLFLASYLISG 121
E VEE H +G EK G+ VL LM + I + L++ + ++S
Sbjct: 19 EEVEEAH---GDYGHVEKEIFMVNGLLSVLG----LMLLFLGIQEVSIASLWVITLILSI 71
Query: 122 WKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKE--YPEGVAVMLFYVIGEFLQDMAVD 179
V + + L + +A +G L EG+ +ML Y E L+
Sbjct: 72 AAVRELVLERRLTVELL-------MAIVGFILAYHGIVFEGLIIMLLYSFAETLEAQVEK 124
Query: 180 KSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSV 239
+ R ++ L + +VRDG++ +V ++K GD+++V+ GE VPVDGV+++ T
Sbjct: 125 LALRRLEEAKRLIPKRVRVVRDGSIEEVDASQVKPGDVVLVRKGEAVPVDGVLLD-TGVF 183
Query: 240 DTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAK 299
D +TGES P TV+ G I SG IN+ +KV+ + EST+ RI+ K
Sbjct: 184 DLRLITGESEPVTVEGGRAIESGAINVGQPVKVKAVKSPLESTIQRIVSSALELLREKGA 243
Query: 300 TEKFITRFAHYYTPAVVG--IATLIATVPPLVFKESFTSWVYRALVILVISCPCALVLSI 357
T++ I R A Y V+G IA I P +++V+L+ CP A +++
Sbjct: 244 TQRLIDRLAPYMIVIVIGAFIAAYITLGPE------------KSVVLLLAGCPSAFIIAS 291
Query: 358 PLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIET-RNGFTE 416
I A GI+ +G L+A V DKTGT+T G K +++ R ++
Sbjct: 292 SAATSYSIATLATRGIVARGGRSLEAAGKIKAVVLDKTGTITMGTLKPSRVVVLRGAASQ 351
Query: 417 EEILRFAALAEAHSNHPIAKAIREAYGKEINEAEITEYEEIAGHGVRARIDSVEVMVGND 476
+ +L A A + S HP++ AI + N + + EE+ G G+RA + +++G++
Sbjct: 352 DGLLNLVAAAASTSLHPLSIAIARRWRPMGN---VEKVEEVPGRGLRAVVSGRTLLLGSE 408
Query: 477 KLLHRS---NIEHDTCKVKGTIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKV 533
+ L E+ AHV DG I +S+E+ E A+ E+KR+G+ +
Sbjct: 409 RFLEEEVGYRPENPCVDEVPVFAHV--DGTTLA-ICMSEEVDEKTKAAINEMKRMGL-NL 464
Query: 534 VMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPV 593
V+ +GD R+ E+IA++LG+D ++AEL PEDK++I+ K+ ++ + +GDG+ND
Sbjct: 465 VLASGDRRNKVEKIARELGIDEYHAELKPEDKLEIVSKVREK--YDPVSMIGDGVNDLEA 522
Query: 594 LARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKL 653
LA +D+GVA+G + DA AD V+++ + P+ ++ R + ++ A VKL
Sbjct: 523 LAASDLGVAVGNI--DAVRNLADAVLVNG-VADAPRLYRMGRSYLAGLKAGLVAATIVKL 579
Query: 654 AFIGLGIFGKATMW-EAVFADVGVALIAVFNAMRVL 688
A I LGI G +W A+ D G +I A+ V+
Sbjct: 580 AVIILGIGGSIPLWLVALLGDDGSTIIGSVAAVAVI 615
>pir||C81321 probable cation-transporting ATPase Cj1161c [imported] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6968594|emb|CAB73415.1| (AL139077) putative
cation-transporting ATPase [Campylobacter jejuni]
Length = 699
Score = 247 bits (624), Expect = 3e-64
Identities = 183/672 (27%), Positives = 346/672 (51%), Gaps = 51/672 (7%)
Query: 5 KLKLEGLDCASCAYEIEEALRK-EGFKFAVVNFATKEAI-IEGDIEKAKEVIKKVEP-DV 61
++K+ + C +C+ IE A +K +G K A V++ + + D +K K++I K++
Sbjct: 5 RIKIGKMTCVNCSNAIERACKKIDGVKDASVSYVNSSGVFLLEDQKKRKDIIAKIKNLGF 64
Query: 62 EVVEEVHIHD----HAHGEFEKRTIYFIGISLVLFTIGILMRYYYAIDNTLVFGLFLASY 117
E++E+ + H E K + I +S+++ + ++ ++ + + F Y
Sbjct: 65 EILEDEQSLNAYKAKKHLELRKNLLLSIVLSVIIMYFEMFVKSSFSQNIQMALSFFGIFY 124
Query: 118 LISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAF---------LIKE----YPEGVAVM 164
G A + + N+ D N L+A+ T+ AF + KE + + ++
Sbjct: 125 C--GRDFFSHAFLGFKSKNL-DMNTLVALGTLSAFVYSFLVYLQIFKEEDLYFSGAMMII 181
Query: 165 LFYVIGEFLQDMAVDKSRRSIKALLALKAEYAN-LVRDGTVVKVKPEELKVGDIIIVKPG 223
F ++G++L+ A K++ + L + + L+ D ++ ++ +K GD+++VK G
Sbjct: 182 SFVLLGKYLESKAKFKAQDYQRILENIDTKKTKILLEDESIKEISSSFVKSGDVLLVKEG 241
Query: 224 EKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTV 283
E + DGV++ G++ +D S L GE +P KEGDE+ +G + L G L+++ ++ +ST+
Sbjct: 242 ESIVADGVVLLGSAELDMSFLNGEFLPVLKKEGDEVQAGAVVLNGALRIKANKKAMDSTL 301
Query: 284 SRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKESFTSWVYRALV 343
+I LV A + K+ + + Y+ ++ A L+ V K + +
Sbjct: 302 EQIKNLVFEAGSIKSPLANLADQISKYFVGGIIFFAFLVFVF--WVLKADLNTAFLHSCA 359
Query: 344 ILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVF 403
+L+ISCPCAL L+ P+ AAK ILIK L+ L FDKTGTLTK
Sbjct: 360 VLLISCPCALGLATPIALVVASANAAKNFILIKNPAALEKLALVKYAFFDKTGTLTKENL 419
Query: 404 KVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKEINEAEITEYEEIAGHGVR 463
+ K + ++++ + + E+ S+HPIAKA+ + + ++ E I G G++
Sbjct: 420 SIFK----HNLSKDDFDKLCQI-ESLSSHPIAKALHKDHFFDLK----GEGRVIVGSGIK 470
Query: 464 ARIDSVEVMVGNDKLLHRSNIE-------HDTCKVKGTIAHVVIDGQYAGYIVISDEIKE 516
+ D+ +VGN + LH + I+ DT K + + + + G +++S+ +K+
Sbjct: 471 YKEDNDNYLVGNAQFLHENEIDTKESDIFFDTFK-EYVRVYFAKNKKCLGGVLLSNALKD 529
Query: 517 DAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEK 576
A V LK+ + K +++GD E+IAK+L +D F+A+L E+K++II+K +
Sbjct: 530 GAKELVLNLKKQNL-KTFILSGDHVKNVEKIAKELQIDEFHAQLKSEEKLQIIQKFK--- 585
Query: 577 GNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARK 636
K +FVGDGINDA L+ A V ++ + ++ A +T D +++ D S + K ++A+K
Sbjct: 586 ---KTLFVGDGINDAAALSAASVSMSF-SKANELAKKTGDFILIKDDLSAIFKCFKLAKK 641
Query: 637 TQRIVWENIIFA 648
T+ I+ N+ +A
Sbjct: 642 TRGIIKLNLFWA 653
>sp|P55989|COPA_HELPY COPPER-TRANSPORTING ATPASE >gi|7428305|pir||H64653
copper-transporting ATPase (EC 3.6.1.-), P-type -
Helicobacter pylori (strain 26695)
>gi|2314221|gb|AAD08117.1| (AE000614)
copper-transporting ATPase, P-type (copA) [Helicobacter
pylori 26695]
Length = 745
Score = 246 bits (622), Expect = 5e-64
Identities = 205/744 (27%), Positives = 362/744 (48%), Gaps = 80/744 (10%)
Query: 2 MPRKLKLEGLDCASCAYEIEEALRKEGF-KFAVVNFATKEAIIEGDIEKAKEVIKKVEPD 60
M +EG+ C +C+ IE +L ++ F K V+ K A IE D + ++
Sbjct: 1 MKESFYIEGMTCTACSSGIERSLGRKSFVKKIEVSLLNKSANIEFDENQTN-----LDEI 55
Query: 61 VEVVEEVHIHDHAHGEFEKRTIYFIGISLVLFTIGILMRYYYAIDNTLVFGLFLAS---- 116
+++E++ EK+ + + L L I L Y ++ L L S
Sbjct: 56 FKLIEKLGYSPKKALTKEKKEFFSPNVKLALAVIFTLFVVYLSMGAMLSPSLLPESLLAI 115
Query: 117 -----YLISGWKVLKSAIVNSLNGNVFDENF------------LIAVATIGAFLIK---- 155
+L + +++ + IV L + + + F LIA+ T A +
Sbjct: 116 DNHSNFLNACLQLIGALIVMHLGRDFYIQGFKALWHRQPNMSSLIAIGTSAALISSLWQL 175
Query: 156 ----------------EYPEGVAVMLFYV-IGEFLQDMAVDKSRRSIKALLALKAEYANL 198
Y E V V+L +V +G+ +++++ DK+ +++AL+ + A
Sbjct: 176 YLVYTNHYTDQWSYGHYYFESVCVILMFVMVGKRIENVSKDKALDAMQALMKNAPKTALK 235
Query: 199 VRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDE 258
+++ ++V + + VGDI+ V PG + VDG IIEG +D S L+GE++P K GD+
Sbjct: 236 MQNNQQIEVLVDSIVVGDILKVLPGSAIAVDGEIIEGEGELDESMLSGEALPVYKKVGDK 295
Query: 259 ILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGI 318
+ SG N ++ T+ ST+S+I+E++ NA + KA+ + + + + P+V+ I
Sbjct: 296 VFSGTFNSHTSFLMKATQNNKNSTLSQIIEMIYNAQSSKAEISRLADKVSSVFVPSVIAI 355
Query: 319 ATLIATVPPLVFKESFTSWVYRALV-----ILVISCPCALVLSIPLGYFGGIGRAAKEGI 373
+ L V ++ + W + + +LVISCPCAL L+ P+ +A+ G+
Sbjct: 356 SILAFVVWLIIAPKPDFWWNFGIALEVFVSVLVISCPCALGLATPMSILVANQKASSLGL 415
Query: 374 LIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHP 433
K + L+ + + + FDKTGTLT G V + ++ E+L A E S H
Sbjct: 416 FFKDAKSLEKARLVNTIVFDKTGTLTNGKPVVKSVHSKIELL--ELLSLALSIEKSSEHV 473
Query: 434 IAKAIREAYGKEINE--AEITEYEEIAGHGVRARID----SVEVMVGNDKLLHRSNIEHD 487
IAK I E Y KE N E++ + G G+ A+ D + VGN + + N
Sbjct: 474 IAKGIVE-YAKEHNAPLKEMSGVKVKTGFGISAKTDYQGTKEIIKVGNSEFFNPIN---- 528
Query: 488 TCKVKGTIAHVVI-------DGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDS 540
T ++K V + + + G V+ D K+ + ++K LG+ +++GD+
Sbjct: 529 TLEIKENGILVFVGRAISEKEDELLGAFVLEDLPKKGVKEHIAQIKNLGI-NTFLLSGDN 587
Query: 541 RDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVG 600
R+ ++ A +LG+DG+ + P+DK+ I++L KEKG ++ VGDG+NDAP LA +DV
Sbjct: 588 RENVQKCAFELGIDGYISNAKPQDKLNKIKEL-KEKGQ-IVMMVGDGLNDAPSLAMSDVA 645
Query: 601 VAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGL-- 658
V M A GSD +++ AD+V ++ + AI++++ T + + EN+ +A FI L
Sbjct: 646 VVM-AKGSDVSVQAADIVSFNNDIKSVYSAIKLSQATIKNIKENLFWAFCYNSVFIPLAC 704
Query: 659 GIFGKAT-MWEAVFADVGVALIAV 681
G+ KA M A + ++L +V
Sbjct: 705 GVLYKANLMLSPAIAGLAMSLSSV 728
>sp|P77871|COA1_HELPY COPPER-TRANSPORTING ATPASE
Length = 745
Score = 245 bits (620), Expect = 9e-64
Identities = 211/743 (28%), Positives = 363/743 (48%), Gaps = 78/743 (10%)
Query: 2 MPRKLKLEGLDCASCAYEIEEALRKEGF-KFAVVNFATKEAIIEGDIEKAK--EVIKKVE 58
M +EG+ C +C+ IE +L ++ F K VN K A IE + + E+ K +E
Sbjct: 1 MKESFYIEGMTCTACSSGIERSLGRKSFVKKIEVNLLNKSANIEFNENETNLDEIFKLIE 60
Query: 59 -----PDVEVVEEVHIHDHAHGEFEKR---TIYFIGISL-VLFTIGILMRYYYAIDN--- 106
P + EE + + T++ + +S+ + + +L + AIDN
Sbjct: 61 KLGYSPKKTLAEEKKEFFSPNVKLALAVIFTLFVVYLSMGAMLSPSLLPKSLLAIDNHSN 120
Query: 107 ----------TLVFGLFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIK- 155
TL+ + + I G+K L N + LIA+ T A +
Sbjct: 121 FLNACLQLIGTLIVMHWGRDFYIQGFKALWHRQPNMSS--------LIAIGTSAALISSL 172
Query: 156 -------------------EYPEGVAVMLFYV-IGEFLQDMAVDKSRRSIKALLALKAEY 195
Y E V V+L +V +G+ +++++ DK+ +++AL+ +
Sbjct: 173 WQLYLVYTDHYTDQWSYGHYYFESVCVILMFVMVGKRIENVSKDKALDAMQALMKNAPKT 232
Query: 196 ANLVRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKE 255
A +++ ++V + + VGDI+ V PG + VDG IIEG +D S L+GE++P K
Sbjct: 233 ALKIQNDQQIEVLVDSIVVGDILKVLPGTLIAVDGEIIEGEGELDESMLSGEALPVYKKV 292
Query: 256 GDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAV 315
GD++ SG N ++ T+ ST+S+I+E++ NA + KA+ + + + + P+V
Sbjct: 293 GDKVFSGTFNSHTSFLMKATQNNKNSTLSQIVEMIHNAQSSKAEISRLADKVSSVFVPSV 352
Query: 316 VGIATLIATVPPLVFKESFTSWVYRALV-----ILVISCPCALVLSIPLGYFGGIGRAAK 370
+ IA L V ++ + W + + +LVISCPCAL L+ + +A+
Sbjct: 353 IAIAILAFVVWLIIAPKPDFWWNFGIALEVFVSVLVISCPCALGLATLMSILVANQKASS 412
Query: 371 EGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHS 430
G+ K + L+ + + + FDKTGTLT G V + ++ E+L A E S
Sbjct: 413 LGLFFKDAKSLEKARLVNTIVFDKTGTLTNGKPVVKSVHSKIELL--ELLSLANSIEKSS 470
Query: 431 NHPIAKAIREAYGKEINE--AEITEYEEIAGHGVRARID----SVEVMVGNDKLLHRSN- 483
H IAK I E Y KE N E++E + G G+ A+ D + VGN + + N
Sbjct: 471 EHVIAKGIVE-YAKEHNAPLKEMSEVKVKTGFGISAKTDYQGTKEIIKVGNSEFFNPINT 529
Query: 484 --IEHDTCKVKGTIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSR 541
I+ + V A + + G V+ D K+ V ++K LG+ +++GD+R
Sbjct: 530 LEIQENGILVLVGRAINEKEDELLGAFVLEDLPKKGVKEHVAQIKNLGI-NTFLLSGDNR 588
Query: 542 DVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGV 601
+ ++ A +LG+DG+ + P+DK+ I++L KEKG ++ VGDG+NDAP LA +DV V
Sbjct: 589 ENVKKCALELGIDGYISNAKPQDKLNKIKEL-KEKGR-IVMMVGDGLNDAPSLAMSDVAV 646
Query: 602 AMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGL--G 659
M A GSD +++ AD+V ++ + AI++++ T + + EN+ +A FI L G
Sbjct: 647 VM-AKGSDVSVQAADIVSFNNDIKSVYSAIKLSQATIKNIKENLFWAFCYNSVFIPLACG 705
Query: 660 IFGKAT-MWEAVFADVGVALIAV 681
+ KA M A + ++L +V
Sbjct: 706 VLYKANIMLSPAIAGLAMSLSSV 728
>sp|P18398|FIXI_RHIME NITROGEN FIXATION PROTEIN FIXI (E1-E2 TYPE CATION ATPASE FIXI)
>gi|95193|pir||C32052 FixI protein - Rhizobium meliloti
>gi|49414|emb|CAA79907.1| (Z21854) FixI [Sinorhizobium
meliloti] >gi|152212|gb|AAA26273.1| (M24144) nitrogen
fixation protein fixI [Sinorhizobium meliloti]
Length = 757
Score = 243 bits (615), Expect = 3e-63
Identities = 170/535 (31%), Positives = 277/535 (51%), Gaps = 18/535 (3%)
Query: 157 YPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVR-DGTVVKVKPEELKVG 215
+ V ++ F +IG L M ++R +I L L A +V DG+ +E+ G
Sbjct: 218 FDASVTLLFFLLIGRTLDHMMRGRARTAISGLARLSPRGATVVHPDGSREYRAVDEINPG 277
Query: 216 DIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVT 275
D +IV GE+VPVDG ++ GTS +D S + GES P V GD + +G +NLTG L + T
Sbjct: 278 DRLIVAAGERVPVDGRVLSGTSDLDRSVVNGESSPTVVTTGDTVQAGTLNLTGPLTLEAT 337
Query: 276 RELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKESFT 335
+S ++ I+ L+E A +A+ + R A YY+PA V + L+ V ++ +
Sbjct: 338 AAARDSFIAEIIGLMEAAEGGRARYRRIADRAARYYSPA-VHLLALLTFVGWMLVEGDVR 396
Query: 336 SWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKT 395
+ A+ +L+I+CPCAL L++P+ GR + G+++K + ++ L + V DKT
Sbjct: 397 HAMLVAVAVLIITCPCALGLAVPVVQVVAAGRLFQGGVMVKDGSAMERLAEIDTVLLDKT 456
Query: 396 GTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKEINEAEITEYE 455
GTLT G ++ + + + AA+A HS HPIA AI+ + G A +
Sbjct: 457 GTLTIG---KPRLVNAHEISPGRLATAAAIA-VHSRHPIAVAIQNSAGAASPIA--GDIR 510
Query: 456 EIAGHGVRARI-DSVEVMVGNDKLLHRSNIEHDTCKVKGTIAHVVIDGQYAGYIVISDEI 514
EI G G+ + D V + D + S + + + A + +D + D+
Sbjct: 511 EIPGAGIEVKTEDGVYRLGSRDFAVGGSGPDG-----RQSEAILSLDFRELACFRFEDQP 565
Query: 515 KEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEK 574
+ + +++ L RLG+ ++ +GD V +A LG+ +YAEL P +KV++
Sbjct: 566 RPASRESIEALGRLGIATGIL-SGDRAPVVAALASSLGISNWYAELSPREKVQVC-AAAA 623
Query: 575 EKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIA 634
E G+ LV VGDGINDAPVL A V +A A +D + AD V M ++ S +P AI+ +
Sbjct: 624 EAGHKALV-VGDGINDAPVLRAAHVSMA-PATAADVGRQAADFVFMHERLSAVPFAIETS 681
Query: 635 RKTQRIVWENIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIAVFNAMRVLR 689
R +++ +N A+G + + + I G AT A A +L+ VFNA+R+ R
Sbjct: 682 RHAGQLIRQNFALAIGYNVIAVPIAILGYATPLVAAVAMSSSSLVVVFNALRLKR 736
>emb|CAC12269.1| (AL445066) heavy-metal transporting P-type ATPase related protein
[Thermoplasma acidophilum]
Length = 672
Score = 243 bits (613), Expect = 6e-63
Identities = 187/632 (29%), Positives = 316/632 (49%), Gaps = 74/632 (11%)
Query: 96 ILMRYYY--AIDNTLVFGLFLASYLISGWKVLKSAI--VNSLNGNVFDENFLIAVATIGA 151
+++ Y Y A+ + ++ L L SG + AI + + +GN+ + L+++ + A
Sbjct: 62 LVLTYIYTGALRDIILLVLSLPVVFYSGTQFYPGAISAIRTRSGNM---DLLVSLGILTA 118
Query: 152 FL----IKEYPEGVAVMLFY-----------VIGEFLQDMAVDKSRRSIKALLALKAEYA 196
F + +P + + Y + G +++ + K+ + LL+L E
Sbjct: 119 FFFSVFVSFFPHAIPHSMVYFDSSDFIVSLILTGSYVESLVKAKASDAGNRLLSLIPETV 178
Query: 197 NLVRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEG 256
+LV DG +V ++ ++ +++ V+PGE VPVDG++ G++ VD+S +TGES+P TV G
Sbjct: 179 HLVSDGGIVDIESSKISPENLVEVRPGETVPVDGIVERGSADVDSSMITGESLPITVNPG 238
Query: 257 DEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVV 316
++ SGM +L G + VRV STV +I ++ AS+ + K ++ F+ Y+ P V+
Sbjct: 239 SKVSSGMKDLNGTIVVRVQAVGPNSTVGKIYSFIKMASSGRTKIQRIADVFSSYFVPVVL 298
Query: 317 GIAT---------LIATVPPLVFKESFTSWVYRALVILVISCPCALVLSIPLGYFGGIGR 367
AT L + P + + S+V ++VI+CPCA+ L+ P+
Sbjct: 299 AAATASFLFWFFYLRSIGDPYFIETAILSFV----SVIVIACPCAIGLAGPITLLIASEG 354
Query: 368 AAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAE 427
+ + GIL+K + +D + + V FDKTGTLT + ++ N + E L AA E
Sbjct: 355 SFEAGILVKNAGAMDRVTKVNRVVFDKTGTLT-----LPEMYVLNYSGDTEALMMAAAIE 409
Query: 428 AHSNHPIAKAIREAYGKEINEAEITEYEEIAGHGVRARIDSVEVMVGNDKLLHRSNIEHD 487
+HSNHP+A+AI + Y I+ + + +E+ G G +E M K+ S D
Sbjct: 410 SHSNHPVARAIVQ-YAGNISHKDADQVKEMPGSG-------IEGMCCGHKISVISGENGD 461
Query: 488 TCKVKGTIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGD-SRDVAEE 546
+ +DG G + I +I+ +A + E+K G+ K+ ++TGD SRD A
Sbjct: 462 --------LRITVDGTVRGVLKIGSKIRPEAEETIAEMKEKGM-KISVLTGDRSRDSASA 512
Query: 547 IAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGAL 606
+ + +G+D L PEDK II K ++ ++FVGDGIND + +ADVGVAMG+
Sbjct: 513 V-ESIGVDEVLTGLSPEDKAAIIRKY--QEAGDYVMFVGDGINDVMAIDQADVGVAMGS- 568
Query: 607 GSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFAL-----------GVKLAF 655
GSD D V++ + + I+ KT V +NII+A+ GV +
Sbjct: 569 GSDITRSQGDFVLLRNDLRAILSIFDISSKTISKVKQNIIWAISYNSALIPVAAGVLVPI 628
Query: 656 IGLGIFGKATMWEAVFADVGVALIAVFNAMRV 687
G GI+ M A FA + V N++R+
Sbjct: 629 FGAGIYSFLPML-AAFAMGMSSSTVVLNSIRL 659
>sp|P37385|ATSY_SYNP7 PROBABLE COPPER-TRANSPORTING ATPASE SYNA >gi|436954|gb|AAB82020.1|
(U04356) copper transporting P-ATPase [Synechococcus
PCC7942]
Length = 790
Score = 235 bits (594), Expect = 1e-60
Identities = 180/632 (28%), Positives = 314/632 (49%), Gaps = 64/632 (10%)
Query: 116 SYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKE------YPEGVAVMLFYVI 169
S L +GW+ L+ N +N V +A++ A L + + E V ++ F ++
Sbjct: 152 SILQAGWQGLRCGAPN-MNSLVLLGTGSAYLASLVALLWPQLGWVCFFDEPVMLLGFILL 210
Query: 170 GEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKP-----------EELKVGDII 218
G L++ A +S+ +++ LLAL+ E L+ + + + +L+ GD +
Sbjct: 211 GRTLEEQARFRSQAALQNLLALQPETTQLLTAPSSIAPQDLLEAPAQIWPVAQLRAGDYV 270
Query: 219 IVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTREL 278
V PG+++PVDG I+ G S++DT+ LTGE +P+ + GD + +G +NL+ L +R +
Sbjct: 271 QVLPGDRIPVDGCIVAGQSTLDTAMLTGEPLPQPCQVGDRVCAGTLNLSHRLVIRAEQTG 330
Query: 279 SESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLI----ATVP----PLVF 330
S++ ++ I+ V A RKA ++F A + V IA L AT+ P V
Sbjct: 331 SQTRLAAIVRCVAEAQQRKAPVQRFADAIAGRFVYGVCAIAALTFGFWATLGSRWWPQVL 390
Query: 331 KESFTSWVYRA-----------------------LVILVISCPCALVLSIPLGYFGGIGR 367
++ + A + +LV++CPCAL L+ P G
Sbjct: 391 QQPLPGLLIHAPHHGMEMAHPHSHSPLLLALTLAISVLVVACPCALGLATPTAILVATGL 450
Query: 368 AAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAE 427
AA++GIL++G + L+ L FDKTGTLT+G F++ +I+ + +L++AA E
Sbjct: 451 AAEQGILVRGGDVLEQLARIKHFVFDKTGTLTQGQFELIEIQPLADVDPDRLLQWAAALE 510
Query: 428 AHSNHPIAKAIREAYGKEINEAEI--TEYEEIAGHGVRARIDSVEVMVGNDKLLHRSNIE 485
A S HP+A A++ A + N A I ++ +++ G GV D + +GN + + +
Sbjct: 511 ADSRHPLATALQTA-AQAANLAPIAASDRQQVPGLGVSGTCDGRSLRLGNPTWVQVATAK 569
Query: 486 HDTCKVKGTIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAE 545
T T + D Q + D+ + +A V+ L+ G V +++GD + A
Sbjct: 570 LPTGSAAATSIWLADDQQLLACFWLQDQPRPEAAEVVQALRSRGA-TVQILSGDRQTTAV 628
Query: 546 EIAKQLGLDG--FYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAM 603
+A+QLGL+ AE+LPEDK I L+ + + +GDGINDAP LA A VG+++
Sbjct: 629 ALAQQLGLESETVVAEVLPEDKAAAIAALQSQ--GDAVAMIGDGINDAPALATAAVGISL 686
Query: 604 GALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGLG---- 659
A GSD A ++A +++ D+ + A +++ R + +N+ +ALG + + L
Sbjct: 687 AA-GSDIAQDSAGLLLSRDRLDSVLVAWNLSQMGLRTIRQNLTWALGYNVVMLPLAAGAF 745
Query: 660 --IFGKATMWEAVFADVGVALIAVFNAMRVLR 689
+G A A + V+ +AV + +LR
Sbjct: 746 LPAYGLALTPAIAGACMAVSSLAVVSNSLLLR 777
>gb|AAB67320.1| (L33259) adenosine triphosphatase [Helicobacter pylori]
Length = 745
Score = 234 bits (590), Expect = 3e-60
Identities = 206/744 (27%), Positives = 358/744 (47%), Gaps = 80/744 (10%)
Query: 2 MPRKLKLEGLDCASCAYEIEEALRKEGF-KFAVVNFATKEAIIEGDIEKAK--EVIKKVE 58
M +EG+ C +C+ IE +L ++ F K VN K A IE + + E+ K +E
Sbjct: 1 MKESFYIEGMTCTACSSGIERSLGRKSFVKKIEVNLLNKSANIEFNENETNLDEIFKLIE 60
Query: 59 -----PDVEVVEEVHIHDHAHGEFEKR---TIYFIGISL-VLFTIGILMRYYYAIDN--- 106
P + EE + + T++ + +S+ + + +L + AIDN
Sbjct: 61 KLGYSPKKTLAEEKKEFFSPNVKLALAVIFTLFVVYLSMGAMLSPSLLPKSLLAIDNHSN 120
Query: 107 ----------TLVFGLFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIK- 155
TL+ + + I G+K L N + LIA+ T A +
Sbjct: 121 FLNACLQLIGTLIVMHWGRDFYIQGFKALWHRQPNMSS--------LIAIGTSAALISSL 172
Query: 156 -------------------EYPEGVAVMLFYV-IGEFLQDMAVDKSRRSIKALLALKAEY 195
Y E V V+L +V +G+ +++++ DK+ +++AL+ +
Sbjct: 173 WQLYLVYTDHYTDQWSYGHYYFESVCVILMFVMVGKRIENVSKDKALDAMQALMKNAPKT 232
Query: 196 ANLVRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKE 255
A +++ ++V + + VGDI+ V PG + VDG IIEG +D S L+GE++P K
Sbjct: 233 ALKIQNDQQIEVLVDSIVVGDILKVLPGTLIAVDGEIIEGEGELDESMLSGEALPVYKKV 292
Query: 256 GDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAV 315
GD++ SG N ++ T+ ST+S+I+E++ NA + KA+ + + + + P+V
Sbjct: 293 GDKVFSGTFNSHTSFLMKATQNNKNSTLSQIVEMIHNAQSSKAEISRLADKVSSVFVPSV 352
Query: 316 VGIATLIATVPPLVFKESFTSWVYRALV-----ILVISCPCALVLSIPLGYFGGIGRAAK 370
+ IA L V ++ + W + + +LVISCP + + ++
Sbjct: 353 IAIAILAFVVWLIIAPKPDFWWNFGIALEVFVSVLVISCPSCFRIGYAMSILVANQKSEF 412
Query: 371 EGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHS 430
I+ K + L+ + + + FDKTGTLT G V + ++ E+L A E S
Sbjct: 413 FRIIFKDAKSLEKARLVNTIVFDKTGTLTNGKPVVKSVHSKIELL--ELLSLANSIEKSS 470
Query: 431 NHPIAKAIREAYGKEINE--AEITEYEEIAGHGVRARID----SVEVMVGNDKLLHRSNI 484
H IAK I E Y KE N E++E + G G+ A+ D + VGN + + N
Sbjct: 471 EHVIAKGIVE-YAKEHNAPLKEMSEVKVKTGFGISAKTDYQGTKEIIKVGNSEFFNPINT 529
Query: 485 ----EHDTCKVKGTIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDS 540
E+ + G + D + G V+ D K+ V ++K LG+ +++GD+
Sbjct: 530 LEIQENGNFSLVGRAINEKED-ELLGAFVLEDLPKKGVKEHVAQIKNLGI-NTFLLSGDN 587
Query: 541 RDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVG 600
R+ ++ A +LG+DG+ + P+DK+ I++L KEKG ++ VGDG+NDAP LA +DV
Sbjct: 588 RENVKKCALELGIDGYISNAKPQDKLNKIKEL-KEKGR-IVMMVGDGLNDAPSLAMSDVA 645
Query: 601 VAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGL-- 658
V M A GSD +++ AD+V ++ + AI++++ T + + EN+ +A FI L
Sbjct: 646 VVM-AKGSDVSVQAADIVSFNNDIKSVYSAIKLSQATIKNIKENLFWAFCYNSVFIPLAC 704
Query: 659 GIFGKAT-MWEAVFADVGVALIAV 681
G+ KA M A + ++L +V
Sbjct: 705 GVLYKANIMLSPAIAGLAMSLSSV 728
>gb|AAF63680.1|AF172726_3 (AF172726) copper P-type ATPase AtkB [Lactobacillus sakei]
Length = 680
Score = 233 bits (588), Expect = 5e-60
Identities = 158/521 (30%), Positives = 271/521 (51%), Gaps = 31/521 (5%)
Query: 159 EGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYAN-LVRDGTVVKVKPEELKVGDI 217
E +++ ++G +++ AV + ++ + AL A LV+DG V ++L+ G
Sbjct: 139 ELATLIVIMLLGHWIEMNAVMSAGSPMEKMAALLPGQAQVLVQDGQQHAVDLKDLQEGQT 198
Query: 218 IIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRE 277
++V GEKVP DG+++ G S V+ S +TGE+ K GD+++ G +N G L V+VT
Sbjct: 199 VLVAAGEKVPADGLVVNGQSQVNESLVTGEAKAVAKKTGDQVIGGTVNGDGTLTVKVTGT 258
Query: 278 LSESTVSRILELVENASARKAKTEKFITRFAHY--YTPAVVGIATLIATVPPLVFKESFT 335
++++++L++ A K+K E + A Y Y V GI I+ F
Sbjct: 259 GESGYLAQVMKLIKQAQQEKSKVEGLADKVAKYLFYAALVAGIIAFIS----WFFLADLN 314
Query: 336 SWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKT 395
+ R + + +I+CP AL L+IPL AA G+LI+ ++ ++V DKT
Sbjct: 315 TAFERMVTVFIIACPHALGLAIPLVVARSTAIAATNGLLIRNRQAIEVADQITMVLMDKT 374
Query: 396 GTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIREAY--GKEINEAEITE 453
GTLT+G FKV ++ ++ +++ + E HS+HP+A I AY ++I ++
Sbjct: 375 GTLTQGAFKVNAVQPTGEMSKTQLMAYMGALERHSSHPLATGIL-AYNDAEKITMSQAEN 433
Query: 454 YEEIAGHGVRARIDSVEVMVGNDKLLHRSNIEHDTCKVKGTIAHVVIDGQYAGYI----- 508
+ I G G+ I+ + L I DT + A G Y+
Sbjct: 434 VQTIQGIGLTGAIEGQTYQIVTADYLQEKQIAFDTAAFETLAA----KGNSISYLNSRSN 489
Query: 509 VISD------EIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLP 562
+ D ++K +A +K LK+ ++ VM+TGD++ VAE++A+QL A L P
Sbjct: 490 CLRDWSRKGVQLKPEALTFIKALKKRHIQP-VMLTGDNQQVAEKVAQQLVGMTVQANLKP 548
Query: 563 EDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDD 622
EDK +++ + KG ++ VGDG+NDAP L RAD+G+A+GA G+D AI++ADV+++
Sbjct: 549 EDKEALVQDYQ-AKGE-VVLMVGDGVNDAPSLTRADIGIAIGA-GTDVAIDSADVILVKS 605
Query: 623 KPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGL--GIF 661
P+ + + +A T R + +N+ + G + I L G+F
Sbjct: 606 NPNDIMHFLNLAHATSRKMTQNLWWGAGYNILAIPLAGGLF 646
>gb|AAF44624.1|AF202779_3 (AF202779) RdxI [Rhodobacter sphaeroides]
Length = 737
Score = 232 bits (586), Expect = 9e-60
Identities = 164/529 (31%), Positives = 264/529 (49%), Gaps = 19/529 (3%)
Query: 162 AVML--FYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIII 219
AVML F + G +L +R + + L AL+ A L+RDG V V EL GD++
Sbjct: 224 AVMLTFFLLAGRYLDHRTRAVARSAAEELAALEVPRAMLLRDGEEVTVPIAELAAGDLVR 283
Query: 220 VKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELS 279
V+PG ++PVDGV+ EG S +D S LTGES+P + +G +NLTG L VRVT
Sbjct: 284 VRPGGRMPVDGVVAEGFSELDRSLLTGESLPVPAGPETVVSAGEVNLTGPLTVRVTAAGR 343
Query: 280 ESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKESFTSWVY 339
+S++ R+ +LV A + K + R + Y+P V ++ V + K + +
Sbjct: 344 DSSLHRMADLVAVAESAKTRYTSLAERASRLYSPLVHILSFTAFGVWMWITKGDVRTSIN 403
Query: 340 RALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLT 399
+ +L+I+CPCAL L++P GR ++G+LIK L+ L + V FDKTGTLT
Sbjct: 404 ISAAVLIITCPCALGLAVPAVVTAASGRLFRKGLLIKDGTALERLAEVDTVVFDKTGTLT 463
Query: 400 KGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIR-EAYGKEINEAEITEYEEIA 458
G + T + T L AA A S HP+A A+ A G+ + A +T+ E+
Sbjct: 464 LGTPEPTNLAT----LPPADLTLAAALAASSAHPLAMALALAARGQGVQPAAVTDLREVP 519
Query: 459 GHGVRARIDSVEVMVGNDKLLHRSNIEHDTCKVKGTIAHVVIDGQYAGYIVISDEIKEDA 518
G G+ R++ V +G E + A + G I SD ++ A
Sbjct: 520 GFGIEGRLEGRTVRLG--------RAEWVGAAPEPVTATYLSTGAATRAITFSDRLRPGA 571
Query: 519 HLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGN 578
AV+ L G +++++++GD+ E+A +LG+ + + LP +K + + L E
Sbjct: 572 EEAVRALAGQG-KRILLLSGDTEGAVAELAGRLGIGEWRSGQLPAEKAQRVADLTAE--G 628
Query: 579 GKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQ 638
+++ VGDG+ND LA A V ++ A DAA +D+V++ + + A +I+ K
Sbjct: 629 RRVLMVGDGLNDTAALAAAHVSIS-PASALDAARVASDIVLLGKDMAPIADAARISVKAT 687
Query: 639 RIVWENIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIAVFNAMRV 687
+ + EN + + + L + G AT A A ++ NA+RV
Sbjct: 688 KRIRENFAISAAYNVVAVPLALVGLATPLAAALAMSLSSISVSLNALRV 736
>gb|AAF64237.1|AF249736_1 (AF249736) heavy metal transporter [Pseudomonas putida]
Length = 342
Score = 229 bits (577), Expect = 1e-58
Identities = 137/346 (39%), Positives = 204/346 (58%), Gaps = 16/346 (4%)
Query: 355 LSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGF 414
+S P+ G+ AA++GILIKG YL+ + +A DKTGT+T G T +
Sbjct: 1 ISTPVTIVSGLAAAARKGILIKGGVYLEGGRQLDFLALDKTGTITHGKPVQTDAKILEPL 60
Query: 415 TEEEILRFAALAEAHSNHPIAKAIREAYGKEINEA--EITEYEEIAGHGVRARIDSVEVM 472
E AA S+HP+++AI + +GKE A E+ ++ +AG GVR I
Sbjct: 61 FEGRAQALAASLGERSDHPVSRAIAQ-FGKEQGLALSEVDDFAALAGRGVRGTIAGEVYH 119
Query: 473 VGNDKLLHRSNI-------EHDTCKVKGTIAHVVID--GQYAGYIVISDEIKEDAHLAVK 523
+GN +L+ + + D + +G +++D G A + V +D +KE + A+
Sbjct: 120 LGNHRLVEELGLCSPELEAQLDALERQGKTVVLLLDRSGPLALFAV-ADTVKESSRQAIA 178
Query: 524 ELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVF 583
EL LG+ K VM+TGD+ A+ IA +G+D LLP DK+K IE L + ++
Sbjct: 179 ELHELGI-KTVMLTGDNPHTAQAIATVVGIDRAEGNLLPGDKLKSIETLYAQ--GHRVGM 235
Query: 584 VGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWE 643
VGDGINDAP LARA++G AM A G+D AIETADV +MDD K+P ++++R++ I+ +
Sbjct: 236 VGDGINDAPALARAEIGFAMAAAGTDTAIETADVALMDDDLRKIPAFVRLSRQSAAILMQ 295
Query: 644 NIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIAVFNAMRVLR 689
NI+ ALG+K F+ + G ATMW AVFAD+GV+L+ VFN +R+LR
Sbjct: 296 NIVLALGIKAIFLAITFAGMATMWMAVFADMGVSLLVVFNGLRLLR 341
>pir||F83451 probable cation-transporting P-type ATPase PA1549 [imported] -
Pseudomonas aeruginosa (strain PAO1)
>gi|9947509|gb|AAG04938.1|AE004583_3 (AE004583) probable
cation-transporting P-type ATPase [Pseudomonas
aeruginosa]
Length = 811
Score = 228 bits (574), Expect = 2e-58
Identities = 166/536 (30%), Positives = 272/536 (49%), Gaps = 32/536 (5%)
Query: 165 LFYVIGEFLQDMAVDKSRRSIKALL-ALKAEYANLVRDGTVVKVKPEELKVGDIIIVKPG 223
LF + G +L+ A +++ S L+ L A L ++ EL+VGD ++V PG
Sbjct: 284 LFLLAGRYLERRARERTAASTAQLVNLLPASCLRLDAANQGERILLSELRVGDRVLVPPG 343
Query: 224 EKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTV 283
+P DGVI++G SSVD S LTGE +P + GD + G +N+ G L V V +S +
Sbjct: 344 AVLPADGVILDGQSSVDESLLTGEYLPHPRQAGDTVTGGTLNVEGPLTVEVGALGDDSRL 403
Query: 284 SRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKESFTSWVYRALV 343
S I+ L+E A A K + + + A ++ V+ +A A V L ++ + L
Sbjct: 404 SAIVRLLERAQADKPRLAELADKVAQWFLLIVLLVA---AAVGALWWQVDHQRAFWVVLS 460
Query: 344 ILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVF 403
+LV +CPCAL L+ P G K G+LI + L+ L V FDKTGTLT+G
Sbjct: 461 LLVATCPCALSLATPTALTAATGSLHKLGLLITRGHVLEGLNHIDTVIFDKTGTLTEGRL 520
Query: 404 KVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKEINEAEITEYEEIAGH--- 460
+ ++ + L AA E S HPIA+ A+G+ A + +A H
Sbjct: 521 TLKQVLPLRDLDADRCLALAAALENRSEHPIAR----AFGRAPEAA-----DSVASHPGL 571
Query: 461 GVRARIDSVEVMVGNDKLLHRSNIEHD-TCKVKGTIAHVVIDGQYAG---YIVISDEIKE 516
G+ ++ + +G + SN+ T + G ++ G G + + D ++
Sbjct: 572 GLEGLVEGRRLRIGQAAFV--SNLGGSATPAMPGDSGQWLLLGDEQGPLAWFGLDDRLRS 629
Query: 517 DAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEK 576
DA + K G R ++++GD+ + +A +LG+D L P+DK+ ++E+L E
Sbjct: 630 DAPALLAACKARGWR-TLLLSGDASPMVASVAAELGIDEARGGLTPDDKLAMLERLHGE- 687
Query: 577 GNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARK 636
+++ +GDG+ND PVLA AD+ VAMG+ +D A +AD V++ ++ L + ++AR+
Sbjct: 688 -GRRVLMLGDGVNDVPVLAGADISVAMGS-ATDLAKTSADAVLLSNRLDSLVQTFRLARR 745
Query: 637 TQRIVWENIIFAL---GVKLAFIGLGIFGKATMWEAVFADVGVALIAVFNAMRVLR 689
T+ I+ EN+ +A G+ L F LG W A+ V +L+ V NA+R+ R
Sbjct: 746 TRHIIIENLAWASLYNGLVLPFAALGWITPG--WAAIGMSVS-SLLVVVNALRLTR 798
>pir||S60899 probable adenosinetriphosphatase (EC 3.6.1.3) - Helicobacter pylori
Length = 611
Score = 225 bits (567), Expect = 1e-57
Identities = 165/544 (30%), Positives = 287/544 (52%), Gaps = 27/544 (4%)
Query: 157 YPEGVAVMLFYV-IGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVG 215
Y E V V+L +V +G+ +++++ DK+ +++AL+ + A +++ ++V + + VG
Sbjct: 59 YFESVCVILMFVMVGKRIENVSKDKALDAMQALMKNAPKTALKIQNDQQIEVLVDSIVVG 118
Query: 216 DIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVT 275
DI+ V PG + VDG IIEG +D S L+GE++P K GD++ SG N ++ T
Sbjct: 119 DILKVLPGTLIAVDGEIIEGEGELDESMLSGEALPVYKKVGDKVFSGTFNSHTSFLMKAT 178
Query: 276 RELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKESFT 335
+ ST+S+I+E++ NA + KA+ + + + + P+V+ IA L V ++ +
Sbjct: 179 QNNKNSTLSQIVEMIHNAQSSKAEISRLADKVSSVFVPSVIAIAILAFVVWLIIAPKPDF 238
Query: 336 SWVYRALV-----ILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIV 390
W + + +LVISCP + + ++ I+ K + L+ + + +
Sbjct: 239 WWNFGIALEVFVSVLVISCPSCFRIGYAMSILVANQKSEFFRIIFKDAKSLEKARLVNTI 298
Query: 391 AFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKEINE-- 448
FDKTGTLT G V + ++ E+L A E S H IAK I E Y KE N
Sbjct: 299 VFDKTGTLTNGKPVVKSVHSKIELL--ELLSLANSIEKSSEHVIAKGIVE-YAKEHNAPL 355
Query: 449 AEITEYEEIAGHGVRARID----SVEVMVGNDKLLHRSNI----EHDTCKVKGTIAHVVI 500
E++E + G G+ A+ D + VGN + + N E+ + G +
Sbjct: 356 KEMSEVKVKTGFGISAKTDYQGTKEIIKVGNSEFFNPINTLEIQENGNFSLVGRAINEKE 415
Query: 501 DGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAEL 560
D + G V+ D K+ V ++K LG+ +++GD+R+ ++ A +LG+DG+ +
Sbjct: 416 D-ELLGAFVLEDLPKKGVKEHVAQIKNLGI-NTFLLSGDNRENVKKCALELGIDGYISNA 473
Query: 561 LPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIM 620
P+DK+ I++L KEKG ++ VGDG+NDAP LA +DV V M A GSD +++ AD+V
Sbjct: 474 KPQDKLNKIKEL-KEKGR-IVMMVGDGLNDAPSLAMSDVAVVM-AKGSDVSVQAADIVSF 530
Query: 621 DDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGL--GIFGKAT-MWEAVFADVGVA 677
++ + AI++++ T + + EN+ +A FI L G+ KA M A + ++
Sbjct: 531 NNDIKSVYSAIKLSQATIKNIKENLFWAFCYNSVFIPLACGVLYKANIMLSPAIAGLAMS 590
Query: 678 LIAV 681
L +V
Sbjct: 591 LSSV 594
>gb|AAC46114.1| (AF016223) CPx-type cation ATPase homolog [Rhodobacter capsulatus]
Length = 694
Score = 224 bits (566), Expect = 2e-57
Identities = 195/719 (27%), Positives = 336/719 (46%), Gaps = 64/719 (8%)
Query: 6 LKLEGLDCASCAYEIEEALRKE-GFKFAVVNFATKEAIIEGDIEKAKEVIKKVEPDVEVV 64
L L CA C ++E + + G + A VN K ++ + + E + VE ++
Sbjct: 2 LSLPTAHCAVCITDVEREMEAQPGVRSARVNLTLKRVSVDAEAGVSAETL--VEALAKIG 59
Query: 65 EEVHIHDH---AHGEFEKR---------TIYFIGISLVLFTIGIL---------MRYYYA 103
E + D + E +KR F ++++L +I + M ++ +
Sbjct: 60 YEAYELDPGMLSATETDKRGRDLLMRIGVAGFAMMNIMLLSIAVWSGAEAATRDMFHWIS 119
Query: 104 IDNTLVFGLFLAS-YLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEYPE--- 159
L +F+ + S W LK VN +V LI ++I F +
Sbjct: 120 AAIALPTVVFVGQPFFASAWGGLKHGRVNM---DVPISLALILASSISIFETMHHGHHAY 176
Query: 160 -GVAVML--FYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGD 216
AVML F ++G +L +R + + L A++ A+L+R+G V +LK GD
Sbjct: 177 FDAAVMLSFFLLVGRYLDYRTRAVARSAAEELAAVEVPRAHLLREGVETIVPVADLKPGD 236
Query: 217 IIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTR 276
I V+PG ++P DG + GTS D S LTGE++P V G + +G +NLTG L +RVT
Sbjct: 237 SIRVRPGGRIPADGEVTSGTSETDRSLLTGETLPVYVGPGTMLSAGEVNLTGPLTLRVTA 296
Query: 277 ELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIA------TLIATVPPLVF 330
+S++ R+ +LV A + K + R A Y+P V ++ + AT L F
Sbjct: 297 AGKDSSLHRMADLVAMAESAKTRYTTLAERAARAYSPLVHALSFSAFGYWMWATGGDLRF 356
Query: 331 KESFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIV 390
+ ++ +L+I+CPCAL L++P G+ ++G+LIK L+ L + V
Sbjct: 357 AVNISA------AVLIITCPCALGLAVPAVITAASGKLFRKGLLIKDGTALERLAEVDTV 410
Query: 391 AFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKA-IREAYGKEINEA 449
FDKTGTLT G + ++T EEE L AA S+HP+A+A + A ++I
Sbjct: 411 VFDKTGTLTMGAPVLEGLDT----IEEETLSVAAALAQASSHPLARALVAAAEARDIRPV 466
Query: 450 EITEYEEIAGHGVRARIDSVEVMVGNDKLLHRSNIEHDTCKVKGTIAHVVIDGQYAGYIV 509
+ + E+ G G+ R+ ++ + +G + + + T H+ +
Sbjct: 467 VLDDLREVPGFGIEGRLGALALRLGRADWVGAAPCD-------STATHLRLGAAEPVTFR 519
Query: 510 ISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKII 569
SD ++ A AV L G ++V+MV+GD +A +L ++ LP +K ++
Sbjct: 520 FSDHLRLGAAEAVALLTAQG-KRVLMVSGDVETAVSALAGKLASPNGHSGALPAEKAALV 578
Query: 570 EKLEKEKGNG-KLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLP 628
L G G +++ VGDG+ND LA A V ++ A DAA +D+V++ + +
Sbjct: 579 ADL---MGQGRRVLMVGDGLNDTAALAAAHVSIS-PASALDAARTASDIVLLGADLAPVG 634
Query: 629 KAIQIARKTQRIVWENIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIAVFNAMRV 687
A++IA + +R + +N + + + + L + G AT A A ++ N+MR+
Sbjct: 635 DALRIAGQARRRIKDNFVISAAYNVVAVPLALVGLATPLAAALAMSTSSITVSLNSMRL 693
>sp|Q59207|FIXI_BRAJA NITROGEN FIXATION PROTEIN FIXI (E1-E2 TYPE CATION ATPASE FIXI)
>gi|1200219|emb|CAA64889.1| (X95634) P-type ATPase
[Bradyrhizobium japonicum] >gi|3021320|emb|CAA06285.1|
(AJ005001) FixI protein [Bradyrhizobium japonicum]
Length = 730
Score = 222 bits (561), Expect = 7e-57
Identities = 186/715 (26%), Positives = 331/715 (46%), Gaps = 50/715 (6%)
Query: 6 LKLEGLDCASCAYEIEEALRK-EGFKFAVVNFATKEAIIEGD---------IEKAKEVIK 55
L +EG+ CA C +IE L A VN + +E I++ +E+
Sbjct: 23 LAVEGVHCAGCMAKIERGLSAIPDVTLARVNLTDRRVALEWKAGTLDPGRFIDRLEELGY 82
Query: 56 KVEPDVEVVEEVHIHDHAHGEFEKRTI---YFIGISLVLFTIGIL----------MRYYY 102
K P E + + A F R + F +++++ +I + R ++
Sbjct: 83 KAYPFE--TESAEVAEVAESRFLLRCLGVAAFATMNVMMLSIPVWSGNVSDMLPEQRDFF 140
Query: 103 AIDNTLVFGLFLASY-----LISGWKVLKSAIVNS---LNGNVFDENFLIAVATIGAFLI 154
+ L+ L A+Y S W+ L + N ++ V + V TI
Sbjct: 141 HWLSALI-ALPAAAYAGQPFFRSAWRALSAKTTNMDVPISIGVILALGMSVVETIHHAEH 199
Query: 155 KEYPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYA-NLVRDGTVVKVKPEELK 213
+ + ++ F ++G FL ++R L ALKAE A V + +V +
Sbjct: 200 AYFDAAIMLLTFLLVGRFLDQNMRRRTRAVAGNLAALKAETAAKFVGPDEISQVPVAAIS 259
Query: 214 VGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVR 273
GDI++++PGE+ VDG +IEG S +D S +TGE++ T ++G + +G +N++G L+VR
Sbjct: 260 PGDIVLLRPGERCAVDGTVIEGRSEIDQSLITGETLYVTAEQGTPVYAGSMNISGTLRVR 319
Query: 274 VTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKES 333
V+ + ++ I L++NA +++ + R + Y P VV LI + ++ S
Sbjct: 320 VSAASEATLLAEIARLLDNALQARSRYMRLADRASRLYAP-VVHATALITILGWVIAGAS 378
Query: 334 FTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFD 393
+ + + +L+I+CPCAL L+IP G K G+L+ + ++ L +A V FD
Sbjct: 379 WHDAIVTGVAVLIITCPCALGLAIPTVQTVASGAMFKSGVLLNSGDAIERLAEADHVIFD 438
Query: 394 KTGTLTKGVFKVTKIETRNGF-TEEEILRFAALAEAHSNHPIAKAIREAYGKEINEAEIT 452
KTGTLT + +E N +I A S+HP+A A+ +A G + I
Sbjct: 439 KTGTLT-----LPDLEVMNAADIPADIFELAGRLALSSHHPVAAAVAQAAGA---RSPIV 490
Query: 453 EYEEIAGHGVRARIDSVEVMVGNDKLLHRSNIEHDTCKVKGTIAHVVIDGQYAGYIV-IS 511
E AG GVRA +D E+ +G + D ++ + V +I+ +
Sbjct: 491 GAVEEAGQGVRADVDGAEIRLGRPSFCGAEALVGDGTRLDPEASIVAFSKGAEKFILWVR 550
Query: 512 DEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEK 571
++ DA + LK + + +++GD + A L + + A + P DK+ IE+
Sbjct: 551 QGLRPDAQAVIAALKARNI-GIEILSGDREPAVKAAAHALAIPEWRAGVTPADKIARIEE 609
Query: 572 LEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAI 631
L++ +++ VGDG+NDAP LA A V ++ + + TAD+V + + + AI
Sbjct: 610 LKRR--GARVLMVGDGMNDAPSLAAAHVSMS-PISAAHLSQATADLVFLGRPLAPVAAAI 666
Query: 632 QIARKTQRIVWENIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIAVFNAMR 686
ARK ++ +N+ A+G + + + I G T A A G +++ + N++R
Sbjct: 667 DSARKALHLMRQNLWLAIGYNVLAVPVAISGVVTPLIAAAAMSGSSILVMLNSLR 721
>gb|AAA62114.1| (U16659) histidine rich P type ATPase [Escherichia coli]
Length = 721
Score = 221 bits (558), Expect = 2e-56
Identities = 161/578 (27%), Positives = 289/578 (49%), Gaps = 31/578 (5%)
Query: 109 VFGLFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEYPEGVAVMLFYV 168
+ L S L++ W + + +VN+ +F AT+ ++
Sbjct: 156 MMSLVSLSLLVTFWYSIYALVVNTFWPTAHVMDFFWEFATLTVIML-------------- 201
Query: 169 IGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIVKPGEKVPV 228
+G ++ A ++ + L AL A++ + + LK ++ V GE P
Sbjct: 202 LGHRIETAATMEAGDATAKLRALLPNTAHVQHGDHFMDMPVSALKPDMVVQVLAGEAFPA 261
Query: 229 DGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILE 288
DGVI+ G S VD S +TGES K G ++ G IN G L V+VT ++S + ++
Sbjct: 262 DGVILSGESQVDESLMTGESRLIDKKPGVSVVGGTINGNGTLLVKVTHVGAQSFIGKLQS 321
Query: 289 LVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVF--KESFTSWVYRALVILV 346
+ + + K++ E + A Y + +A LIA + +++ + A+ +LV
Sbjct: 322 TLAASQSAKSRVETIADQVASY----LFWVALLIAGLSLMIWTPTHGLGFAINIAVTVLV 377
Query: 347 ISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVT 406
I+CP AL L++PL AA +GILIK L + + V DKTGTLT G FKV
Sbjct: 378 IACPHALGLAVPLVIQRTKAIAATQGILIKNHKALSSANHLTYVLMDKTGTLTTGQFKVM 437
Query: 407 KIETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKEINEAEI---TEYEEIAGHGVR 463
++ T N F ++E L A +A S HP+A+ I +Y K+ +A + T+ E +AG+G+
Sbjct: 438 QVVTDN-FDQKEALGIMAALDAQSTHPLAQGI-VSYAKQ-QQAPVLSATDVENMAGYGIA 494
Query: 464 ARIDSVEVMVGNDKLLHRSNIEHDTCKVKGTIAHVVIDGQYAGYIVISDEIKEDAHLAVK 523
++ ++ +++ L +I + GTI +++ + DEIK +
Sbjct: 495 GMVNDKHYLLVSERYLKDHHIHYTPLVADGTIYYLLQHDHVVAAVAQGDEIKATTPTFIN 554
Query: 524 ELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVF 583
LK + ++VTGD+ VA+ +A QLG+ +A++ P++K+ +++ +K+ G+++
Sbjct: 555 YLKAQHLIP-ILVTGDNAQVAQAVADQLGITEIHAQVSPQEKIALVKDYQKQ---GQVMM 610
Query: 584 VGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWE 643
+GDGINDAP LA+AD+ VA+GA G+ A AD V++ ++ + +++A++ R E
Sbjct: 611 IGDGINDAPALAQADLSVAIGA-GTQVAQAAADTVLIANQLPTIIDFLKLAKRADRKQIE 669
Query: 644 NIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIAV 681
N+ + G + + L AT + +G L+++
Sbjct: 670 NLWWGAGYNIIALPLAAGALATFGIMLNPMIGAILMSL 707
>pir||JC2465 copper-transporting ATPase (EC 3.6.1.-) HRA-2 - Enterobacteriaceae
spp
Length = 708
Score = 221 bits (558), Expect = 2e-56
Identities = 161/578 (27%), Positives = 289/578 (49%), Gaps = 31/578 (5%)
Query: 109 VFGLFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEYPEGVAVMLFYV 168
+ L S L++ W + + +VN+ +F AT+ ++
Sbjct: 143 MMSLVSLSLLVTFWYSIYALVVNTFWPTAHVMDFFWEFATLTVIML-------------- 188
Query: 169 IGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIVKPGEKVPV 228
+G ++ A ++ + L AL A++ + + LK ++ V GE P
Sbjct: 189 LGHRIETAATMEAGDATAKLRALLPNTAHVQHGDHFMDMPVSALKPDMVVQVLAGEAFPA 248
Query: 229 DGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILE 288
DGVI+ G S VD S +TGES K G ++ G IN G L V+VT ++S + ++
Sbjct: 249 DGVILSGESQVDESLMTGESRLIDKKPGVSVVGGTINGNGTLLVKVTHVGAQSFIGKLQS 308
Query: 289 LVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVF--KESFTSWVYRALVILV 346
+ + + K++ E + A Y + +A LIA + +++ + A+ +LV
Sbjct: 309 TLAASQSAKSRVETIADQVASY----LFWVALLIAGLSLMIWTPTHGLGFAINIAVTVLV 364
Query: 347 ISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVT 406
I+CP AL L++PL AA +GILIK L + + V DKTGTLT G FKV
Sbjct: 365 IACPHALGLAVPLVIQRTKAIAATQGILIKNHKALSSANHLTYVLMDKTGTLTTGQFKVM 424
Query: 407 KIETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKEINEAEI---TEYEEIAGHGVR 463
++ T N F ++E L A +A S HP+A+ I +Y K+ +A + T+ E +AG+G+
Sbjct: 425 QVVTDN-FDQKEALGIMAALDAQSTHPLAQGI-VSYAKQ-QQAPVLSATDVENMAGYGIA 481
Query: 464 ARIDSVEVMVGNDKLLHRSNIEHDTCKVKGTIAHVVIDGQYAGYIVISDEIKEDAHLAVK 523
++ ++ +++ L +I + GTI +++ + DEIK +
Sbjct: 482 GMVNDKHYLLVSERYLKDHHIHYTPLVADGTIYYLLQHDHVVAAVAQGDEIKATTPTFIN 541
Query: 524 ELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVF 583
LK + ++VTGD+ VA+ +A QLG+ +A++ P++K+ +++ +K+ G+++
Sbjct: 542 YLKAQHLIP-ILVTGDNAQVAQAVADQLGITEIHAQVSPQEKIALVKDYQKQ---GQVMM 597
Query: 584 VGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWE 643
+GDGINDAP LA+AD+ VA+GA G+ A AD V++ ++ + +++A++ R E
Sbjct: 598 IGDGINDAPALAQADLSVAIGA-GTQVAQAAADTVLIANQLPTIIDFLKLAKRADRKQIE 656
Query: 644 NIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIAV 681
N+ + G + + L AT + +G L+++
Sbjct: 657 NLWWGAGYNIIALPLAAGALATFGIMLNPMIGAILMSL 694
>pir||D82919 copper-transporting P-type ATPase UU203 [imported] - Ureaplasma
urealyticum >gi|6899169|gb|AAF30610.1|AE002120_2
(AE002120) copper-transporting P-type ATPase [Ureaplasma
urealyticum]
Length = 709
Score = 217 bits (546), Expect = 4e-55
Identities = 164/633 (25%), Positives = 306/633 (47%), Gaps = 64/633 (10%)
Query: 85 IGISLVLFTIGILMR--YYYAIDNTLVFG--LFLASYLIS---GWKVLKSAIVNSLNGNV 137
I I L++F + + + +ID ++G +F+ S I G+ K A
Sbjct: 33 ISIPLMVFEMLFMFKSNLILSIDGYFIYGWIVFVLSIFIVFGLGFSFFKGAFFEVFKWKK 92
Query: 138 FDENFLIAVATIGAFLIKEYP-----------------EGVAVMLFYVIGEFLQDMAVDK 180
+ L+ ++T AF+ Y ++ +G+ + D K
Sbjct: 93 PGMSLLVVISTCVAFIYSTYSLISNTIIYEPKLHGFFETACMIIATMSVGQLVSDRIKLK 152
Query: 181 SRRSIKALLALKAEYANLVRDGT--VVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSS 238
+ + +++L L+ + N T V + + K+ + +VK GE VP+DGV+ +
Sbjct: 153 ANQDLQSLNNLQVKKYNSYDLNTKQVSEKVVFQAKINEYALVKKGEIVPLDGVLYSQIAE 212
Query: 239 VDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKA 298
VD S+LTGE+ P ++I++G IN+ ++T+ ++ST+ +I+ V ++ K
Sbjct: 213 VDESSLTGEARPILKTINNDIIAGSINVGDNFIFKITKLYNDSTIKKIINGVNQIASSKP 272
Query: 299 KTEKFITRFAHYYTPAVVGIATLI----ATVP-----PLVF---------KESFTSWVYR 340
K + + + ++TP ++ +A L A VP P+ F + Y
Sbjct: 273 KIQVVADKISLWFTPFILLMAILAFLLQAFVPSIQELPIAFLNLHGSNNDSNLYEKAAYV 332
Query: 341 ALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTK 400
A+ +LVISCPCA +++PL G G AK GI SN + +K + +AFDKTGTLT
Sbjct: 333 AVSVLVISCPCAFGIAVPLAVLIGAGHGAKSGITFNNSNIFEKIKKVNAIAFDKTGTLTY 392
Query: 401 GVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAI--REAYGKEINEAEITEYEEIA 458
G K++ + ++ L E S HP+AK+ + ++ + +E+A
Sbjct: 393 G-----KLQLKQVIGNDQFLDLIYQMELISLHPLAKSFVTYAIINNIVMSTKLIDIKEVA 447
Query: 459 GHGVRAR-IDSVEVMVGNDKLLHRSNIEHDTCKVKGTIAHVV--------IDGQYAGYIV 509
G G+ A+ +D + ++ + + + K + + + I+ + +V
Sbjct: 448 GVGIIAKDVDGNIYELTSEHYANENQFDFSLINQKSSTSTNLLASNIIFSINKKVQSILV 507
Query: 510 ISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKII 569
DEI+ DA+ +K L + + M+TGDS +VA++IAK+LG+ FYA++ PE+K II
Sbjct: 508 FEDEIRADAYETIKVLHENNI-ETYMITGDSFNVAQKIAKELGIKHFYAQVKPEEKANII 566
Query: 570 EKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPK 629
+K++ ++ +++VGDGIND L +A+V +++G + A AD+ ++ + K
Sbjct: 567 KKIQNDQKT--VMYVGDGINDLLALKQANVSISIGET-NKATNAVADISLIKPDILNIYK 623
Query: 630 AIQIARKTQRIVWENIIFALGVKLAFIGLGIFG 662
I++ + T+ + ++++A G L FI L + G
Sbjct: 624 VIKLTKITKMFIVSSLLWAFGYNLIFIPLALIG 656
>dbj|BAA83939.1| (AB024559) YKVW [Bacillus halodurans]
Length = 329
Score = 213 bits (536), Expect = 6e-54
Identities = 127/337 (37%), Positives = 199/337 (58%), Gaps = 20/337 (5%)
Query: 365 IGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAA 424
I A++GIL+KG +L+ L +AFDKTGTLTKG +VT + R+G T+EE+L +
Sbjct: 1 ISNGARKGILLKGGVHLENLGQLRAIAFDKTGTLTKGTPEVTDVIVRDGMTKEELLTYVV 60
Query: 425 LAEAHSNHPIAKAI-REAYGKEINEAEITEYEEIAGHGVRARIDSVEVMVGNDKLLHRSN 483
E +SNHP+A AI R A ++ + E++AG GV A ++ + +G + +
Sbjct: 61 SIEKYSNHPLASAIVRHASTCMNDQLKPVNMEDVAGFGVSAYLNGISWKIGKADFVGKVE 120
Query: 484 IEHDTCKVKGTIA-HVVIDGQ----------YAGYIVISDEIKEDAHLAVKELKRLGVRK 532
E + KG +A + +G+ AG I + D++++D A+++L++ G+R
Sbjct: 121 AE----QFKGGVATRLAEEGKTIVFARDEQGIAGVIALKDQVRKDTLAAIQQLQKAGIR- 175
Query: 533 VVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAP 592
+M+TGDS A IAK+ G+D + AE LPE KV ++KL ++ G + VGDGINDAP
Sbjct: 176 TIMLTGDSEKTAAAIAKESGIDTYVAECLPETKVDEMKKL--KQAYGTVAMVGDGINDAP 233
Query: 593 VLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVK 652
LA A VG+AMG G+D A+ETADVV+M + ++ +AIQ+++K RIV +NI+F++ V
Sbjct: 234 ALATASVGIAMGE-GTDVALETADVVLMKNHLPRIAEAIQLSKKMNRIVKQNIVFSIVVI 292
Query: 653 LAFIGLGIFGKATMWEAVFADVGVALIAVFNAMRVLR 689
LA I + V G ++ + N +R+LR
Sbjct: 293 LALIASNFMQFLHLPMGVIGHEGSTILVILNGLRLLR 329
>gb|AAG20331.1| (AE005106) heavy-metal transporting CPx-type ATPase; Cpx
[Halobacterium sp. NRC-1]
Length = 801
Score = 207 bits (521), Expect = 4e-52
Identities = 189/740 (25%), Positives = 322/740 (42%), Gaps = 74/740 (10%)
Query: 6 LKLEGLDCASCAYEIE-EALRKEGFKFAVVNFATKEAIIEGDIEKA-KEVIKKVEPDVEV 63
L + G+ CA+C +E +A EG + A ++ T+ + D E +E ++ +
Sbjct: 71 LSVSGMHCATCEAFVEAQATDTEGVRAASASYPTETLKVTYDPETVDREAVRAAVDGLGY 130
Query: 64 VEEVHIHDHAHGEFEKRTIY-----FIGISLVLFTIGILMRYYYAIDNT---LVFGLFLA 115
D A + E F G+ +L+ + L Y + + L G
Sbjct: 131 SATERDGDAAADDDESEVGRLLVGGFFGMMTMLWYVLFLYPAYLDVPSAAQLLDLGGLAG 190
Query: 116 SYLIS-------------GWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKE------ 156
SYL++ G+ + + A V SL + + L+ +A A++
Sbjct: 191 SYLLANVWLMATVVLAYTGYPLFRGAYV-SLRAGHPNMDLLVGIAAGAAYVFSTATILTG 249
Query: 157 -----YPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVR-DGTVVKVKPE 210
+ + V+L +G++ + + + L + + A R DG V E
Sbjct: 250 GREVYFDVAIVVVLAVTVGDYYEGRVKRAAAGRLADLTEERVDDATRRRADGATETVAIE 309
Query: 211 ELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLL 270
EL+ GD ++V GE++PVDGV+ G+++VD S +TGES P GD+ + G + G L
Sbjct: 310 ELQAGDEVVVGTGERIPVDGVVTSGSATVDESLVTGESTPVGATPGDDAVGGAVVTDGRL 369
Query: 271 KVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVF 330
V V + + ST+ R++ ++ + + + ++ + R A + P VV +A + L
Sbjct: 370 VVAVGDD-AASTLDRVVRVLWDVQSARPGVQRLVDRVAAVFVPLVVVLAGVAGGWHLLAG 428
Query: 331 KESFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIV 390
+ + L +LV+SCPCAL L+ PL G+ A G+++ + +A V
Sbjct: 429 GAAANEALLVGLSVLVVSCPCALGLATPLAVARGVQEALDGGVVVTDVSAFEAAPAVDTV 488
Query: 391 AFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKEINEAE 450
FDKTGTLT G +V R+ ++ +L AA E +++HP+A AI + +
Sbjct: 489 VFDKTGTLTTGEMRV-----RDVVGDDGVLARAAAVEQYADHPVAAAITD---DATPAGD 540
Query: 451 ITEYEEIAGHGV-----------RARIDSVEVMVGNDKLLHRSN--------IEHDTCKV 491
I ++E + G GV A D+ V+ GN L +
Sbjct: 541 IDDFERVPGRGVAGSLAVRPDGAAAAADAPRVVAGNRALFDDRGWRVPEAYAERAGDARA 600
Query: 492 KGTI-AHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQ 550
G + V DG+ G +V D +++ V L G R VV+VTGD + A
Sbjct: 601 NGNVPVFVGWDGEARGVVVAGDRPRDEWTDVVSTLDADG-RDVVVVTGDDPEAAARFRDH 659
Query: 551 LGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAM--GALGS 608
+ +A + PE K + + L + + VGDG+NDAP LA AD+GVA+ AL +
Sbjct: 660 DAIAAVFAGVPPEGKTEAVRSLRAD--GDTVAMVGDGVNDAPALAAADLGVALDHAALAA 717
Query: 609 DAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGLGIFGKATMWE 668
DA AD V+ + +P+ + T + +N+ +A + L + G
Sbjct: 718 DA----ADAVVTTEDLGAVPRVFALTDATNGRIRQNLAWAFCYNAIAVPLAVAGVLNPLF 773
Query: 669 AVFADVGVALIAVFNAMRVL 688
A A +L+ V N+ R L
Sbjct: 774 AAGAMTVSSLLVVGNSTRSL 793
>pir||A81338 H+/K+-exchanging ATPase (EC 3.6.1.36) B chain Cj0677 [imported] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6968135|emb|CAB72951.1| (AL139076)
potassium-transporting ATPase B chain [Campylobacter
jejuni]
Length = 681
Score = 201 bits (505), Expect = 3e-50
Identities = 158/564 (28%), Positives = 272/564 (48%), Gaps = 60/564 (10%)
Query: 102 YAIDNTLVFGLFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEYPEGV 161
+ + N ++F + + S L ++ S NGN + + I + I +
Sbjct: 29 FMVKNPVMFMVEVGSILT----LILSIFPTLFNGNSDERIYNILITFI-----------L 73
Query: 162 AVMLFYVIGEFLQDMAVDKSRRSIKALLALK--AEYANLVRDGTVVKVKPEELKVGDIII 219
++LF+ F + +A + + L K ++ ++ DG+ + ELK+GDI++
Sbjct: 74 FIILFFA--NFAESIAEGRGKAQAATLRQSKKDSKARHIKSDGSEEMLNSSELKIGDIVL 131
Query: 220 VKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDE---ILSGMINLTGLLKVRVTR 276
VK GE +P DG IIEGT+SVD SA+TGES P + G + + G LT LK+++
Sbjct: 132 VKAGELIPNDGEIIEGTASVDESAITGESAPVMREAGGDFSSVTGGTTVLTDFLKIKILV 191
Query: 277 ELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKESF-- 334
ES + +++ LVE A+ +K E + V+ ++ L+ V F +
Sbjct: 192 GAGESFLDKMINLVEGAARQKTPNEIALNTLL-----IVLSLSFLMVVVSLYPFMQFLGV 246
Query: 335 ---TSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVA 391
SW+ LV L+ + L+ +I + G+ R + ++ +++ D +
Sbjct: 247 SLPISWLVALLVCLIPTTIGGLLSAIGI---AGMDRVTRFNVIALSGKAVESCGDVDTMI 303
Query: 392 FDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAK---AIREAYGKEINE 448
DKTGT+T G + G ++EE+++ L+ P K A+ + G E+
Sbjct: 304 LDKTGTITFGNRLANEFYEVQGISKEEMIKACVLSSLKDETPEGKSIVALAQKMGYELEG 363
Query: 449 AEITEYEEIAGH----GV---------RARIDSVEVMVGNDKLLHRSNIEHDTCKVK--- 492
+I E+ E + GV + D++ + S++E ++
Sbjct: 364 NDIKEFIEFSAQNRMSGVDLQDNTKIRKGAFDAIRAYISEMNGKIPSDLETKVMEISNLG 423
Query: 493 GTIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLG 552
GT V + + G I + D +K EL+++G+ K +M TGD+ A I K+ G
Sbjct: 424 GTPLVVCKNEKILGVIYLKDTVKPGLKERFDELRKMGI-KTLMCTGDNPLTAATITKEAG 482
Query: 553 LDGFYAELLPEDKVKIIEKLEKEKGNGKLV-FVGDGINDAPVLARADVGVAMGALGSDAA 611
LDGF AE PEDK+K I +KE+ GK+V GDG NDAPVL +ADVG+AM + G+ AA
Sbjct: 483 LDGFIAECKPEDKIKAI---KKEQAQGKIVAMTGDGTNDAPVLTQADVGIAMNS-GTQAA 538
Query: 612 IETADVVIMDDKPSKLPKAIQIAR 635
E A+++ +D P+K+ + ++I +
Sbjct: 539 KEAANMIDLDSNPTKILEVVEIGK 562
>sp|O32328|ATKB_CLOAB POTASSIUM-TRANSPORTING ATPASE B CHAIN (ATP PHOSPHOHYDROLASE
[POTASSIUM-TRANSPORTING] B CHAIN)
>gi|11267157|pir||T46843 H+/K+-exchanging ATPase (EC
3.6.1.36) chain B [imported] - Clostridium
acetobutylicum >gi|2275250|gb|AAC45478.1| (U44892) KdpB
[Clostridium acetobutylicum]
Length = 685
Score = 198 bits (498), Expect = 2e-49
Identities = 159/569 (27%), Positives = 277/569 (47%), Gaps = 71/569 (12%)
Query: 124 VLKSAIVNS---LNGNVFDENFLIAVATIGAFL-----------------IKEYPEGVAV 163
+LK AI+ S + +N ++ V +G F+ ++ Y V +
Sbjct: 13 ILKEAIIESFKKIKPKYMMKNPVMFVVEVGFFVTILLTIFPSIFGDKGHNLRVYNLIVTI 72
Query: 164 MLFYVI--GEFLQDMAVDKSRRSIKALLALKAE-YANLV-RDGTVVKVKPEELKVGDIII 219
+LF + F + +A + + AL + + A L+ +DG++ + ELK GD+++
Sbjct: 73 ILFITVLFANFAESVAEGRGKAQADALKKTRKDTIAKLIGKDGSIKTINANELKKGDVVL 132
Query: 220 VKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILS---GMINLTGLLKVRVTR 276
V+ G+ +P DG +++G +SVD SA+TGES P + G + S G ++ LKV +T
Sbjct: 133 VENGDVIPNDGEVVDGVASVDESAITGESAPVMKEPGGDFASVTGGTKVVSDWLKVEITA 192
Query: 277 ELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFK--ESF 334
ES + +++ LVE AS +K E + T ++ + L+A P + +
Sbjct: 193 TPGESFLDKMINLVEGASRQKTPNEIALNTILVSLT--LIFLIVLVALYPMATYTGVKIP 250
Query: 335 TSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDK 394
S + R LV L+ + AL+ +I + G+ R + ++ ++A D + DK
Sbjct: 251 MSTLIRLLVCLIPTTIGALLSAIGI---AGMDRVTRFNVIAMSGKAVEACGDVDTMILDK 307
Query: 395 TGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKEI------NE 448
TGT+T G T G +++++ ++ + + P K+I E GK++ +
Sbjct: 308 TGTITYGNRLAADFITVGGADKQKLIDYSVMCSLKDDTPEGKSIVE-LGKQLGITIDTKK 366
Query: 449 AEITEYEEI--------------------AGHGVRARIDSVEVMVGNDKLLHRSNIEHDT 488
E E+EE A ++ R+ ++ ++ D +
Sbjct: 367 YESIEFEEFTAQTRMSGIKLENGTAVKKGAYDAIKKRVQELKGVIPKD----LDEAVNKV 422
Query: 489 CKVKGTIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIA 548
K+ GT V +D + G I + D +K + L+ +G+ K +M TGD+ A IA
Sbjct: 423 AKLGGTPLVVCVDNKIYGVIYLKDTVKPGLVERFERLREIGI-KTIMCTGDNPLTAATIA 481
Query: 549 KQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLV-FVGDGINDAPVLARADVGVAMGALG 607
K+ G+DGF AE PEDK IE ++KE+ GKLV GDG NDAP LA+ADVG+AM + G
Sbjct: 482 KEAGVDGFIAECKPEDK---IEAIKKEQDEGKLVAMTGDGTNDAPALAQADVGLAMNS-G 537
Query: 608 SDAAIETADVVIMDDKPSKLPKAIQIARK 636
+ AA E A++V +D P+K+ + ++I ++
Sbjct: 538 TTAAKEAANMVDLDSDPTKVLEVVEIGKQ 566
>sp|P73867|ATKB_SYNY3 POTASSIUM-TRANSPORTING ATPASE B CHAIN (ATP PHOSPHOHYDROLASE
[POTASSIUM-TRANSPORTING] B CHAIN)
>gi|7436341|pir||S75067 H+/K+-exchanging ATPase (EC
3.6.1.36) chain B - Synechocystis sp. (strain PCC 6803)
>gi|1653012|dbj|BAA17929.1| (D90910)
potassium-transporting ATPase B chain [Synechocystis
sp.]
Length = 690
Score = 187 bits (469), Expect = 5e-46
Identities = 159/560 (28%), Positives = 268/560 (47%), Gaps = 46/560 (8%)
Query: 163 VMLFYVI-GEFLQDMAVDKSRRSIKALLALKAE-YAN-LVRDGTVVKVKPEELKVGDIII 219
++LF V+ F + +A + + AL + + + YA ++ DG++ V L+ GD I+
Sbjct: 87 ILLFTVLFANFAEAVAEGRGKAQADALRSTQTQTYAQRILADGSLEMVSSTHLRKGDRIV 146
Query: 220 VKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTGLLK----VRVT 275
V G+ +P DG ++EG +SVD SA+TGES P + G ++ S + T ++ +RVT
Sbjct: 147 VSVGDIIPADGEVLEGVASVDESAITGESAPVLKEPGSDVASSVTGGTRIISDELIIRVT 206
Query: 276 RELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKESFT 335
+ + + R+++LVE A K E +T T + ++AT+PP
Sbjct: 207 ADPGKGFIDRMIDLVEGAERSKTPNEIALTVLLAVLT---LVFLIVVATLPPPANYIDSP 263
Query: 336 SWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKT 395
+ + +LV P + + G+ R A+ ++ ++A D + + DKT
Sbjct: 264 VSITLLIALLVALIPTTIGGLLSAIGIAGMDRVAQFNVVATSGRAVEACGDINTLVLDKT 323
Query: 396 GTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAI---REAYGKEIN----E 448
GT+T G NG + +E+ A A P K+I E G ++ +
Sbjct: 324 GTITLGNRLAETFLPVNGHSLKEVAAIALAASIFDTTPEGKSIVRLAEKMGATLDFDRQQ 383
Query: 449 AEITEYE---EIAGHGV-------RARIDSVEVMVGNDKLLHRSNIEHDTCKVK---GTI 495
AE E+ ++G + + +D++ V + + ++ KV GT
Sbjct: 384 AEGVEFSARTRMSGTDLPDGSEVRKGAVDAIRGFVRSRGGKSPTGLDEAYGKVSHLGGTP 443
Query: 496 AHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDG 555
V + + G I + D IK +L+R+GVR VM+TGD+R A IAK+ G+D
Sbjct: 444 LAVCRNDEIYGVIYLKDIIKPGIQERFNQLRRMGVR-TVMLTGDNRITASVIAKEAGVDD 502
Query: 556 FYAELLPEDKVKIIEKLEKEKGNGKLV-FVGDGINDAPVLARADVGVAMGALGSDAAIET 614
F AE PEDK+++I ++E+ GKLV GDG NDAP LA+A+VG+AM + G+ AA E
Sbjct: 503 FIAEATPEDKIQVI---QQEQAAGKLVAMTGDGTNDAPALAQANVGLAMNS-GTQAAKEA 558
Query: 615 ADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLA---------FIGLGIFGKAT 665
A++V +D P+KL + I ++ F+L +A F G+GI G
Sbjct: 559 ANMVDLDSDPTKLIDLVTIGKQLLITRGALTTFSLANDIAKYFAIIPAMFAGIGI-GALN 617
Query: 666 MWEAVFADVGVALIAVFNAM 685
+ + V ++NA+
Sbjct: 618 IMDLKSPQSAVLSALIYNAL 637
>pir||E71813 probable component of cation transport for cbb3-type oxidase -
Helicobacter pylori (strain J99)
>gi|4156001|gb|AAD06962.1| (AE001561) putative component
of cation transport for cbb3-type oxidase [Helicobacter
pylori J99]
Length = 788
Score = 186 bits (468), Expect = 6e-46
Identities = 174/721 (24%), Positives = 322/721 (44%), Gaps = 56/721 (7%)
Query: 6 LKLEGLDCASCAYEIEEAL-RKEGFKFAVVNFATKEAIIEGDIE-KAKEVIKKVEPDVEV 63
L LE C +C + ++ L R +G K VNF T I D KE+I+K+E
Sbjct: 86 LLLEKTHCNACLWLNQKVLERLKGVKKVSVNFTTHHLQIVFDKSLNPKEIIQKIESLGYG 145
Query: 64 VEEVHIHDHAHGEFEKRTIYFIGISLVLFTIGILM------------------RYYYAID 105
+ + ++ +++ Y + +S+ F LM Y +D
Sbjct: 146 AKIYNAQNYTLKAQKEQRSYLLTLSVGFFATMNLMFIAIAKYASYGSASYGGANYGGGMD 205
Query: 106 NTLVFGLFLASYLIS-------GWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEYP 158
+ L L S +S G +K A NG V + ++ + AF+ Y
Sbjct: 206 KLMQRNLDLVSLFLSLLVLVVVGRFFIKGAFYGLKNG-VLGMDLSVSFGALSAFVYSLYA 264
Query: 159 ---------EGVAVMLFYVIG-EFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVK 208
E + +L V G +FL+ A + AL + + +V +G ++
Sbjct: 265 MLVSQETYFEASSTILTLVFGSKFLELKARLFANEKCLALESHEIHSVIVVENGKQIEKH 324
Query: 209 PEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTG 268
P+++ +G ++ V G K+ +DGV++ ++SVD S ++GE P + D IL G +N+
Sbjct: 325 PKDVAIGSVVWVPSGAKIALDGVLLN-SASVDASLISGEFKPLELGVNDPILGGYVNVGV 383
Query: 269 LLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPL 328
+V+ S +S +LE ++ + K E + A ++ AV+ +A + +
Sbjct: 384 PFSYQVSATFQNSRLSSLLETLKKSFLEKPLIESSANKIADIFSKAVLFLAFVSFLLWQF 443
Query: 329 VFKESFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDAS 388
+F + + +LVISCPCA L+ P+ IG I+ K + +L+ L
Sbjct: 444 GLGGNFEKALMVCISVLVISCPCAFALATPIALV--IGVFKNPLIVFKEALFLETLAKVK 501
Query: 389 IVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKEINE 448
+ DKTGTLT+ + + F E + E +++ I K + G E++
Sbjct: 502 KIFIDKTGTLTQKEVLLKEKIIHEEFDERLLKSLLKTREHLAHNAILKTLD---GDEVDL 558
Query: 449 AEITEYEEIAGHGVRARIDSVEVMVGNDKLLHRSNIEHDTCKVKGTIAHVVIDGQYAGYI 508
+I E HG++A + ++VG+ K L+ ++ + + +
Sbjct: 559 EKI----EFFAHGLKASYQNETLLVGSLKFLNAMGVDLKVKESANIMVGFAKNKTLCALF 614
Query: 509 VISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKI 568
++ + +K +A ++ L+ G+ ++ +++GD+ +E AK+LG+ ++A L PEDK +I
Sbjct: 615 ILEERLKANAKEVIQALQNQGL-ELEILSGDNESSVKECAKKLGISKYHAHLTPEDKAQI 673
Query: 569 IEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLP 628
I + G VGDG NDA LA V++G S + D++++++ S L
Sbjct: 674 ISSYK-----GVCAMVGDGNNDA--LALKQASVSLGFEKSALSKSACDILLLEEDLSLLE 726
Query: 629 KAIQIARKTQRIVWENIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIAVFNAMRVL 688
KA A+K ++V +NI+ +L I + + G A + G +L+ V N++R+
Sbjct: 727 KAFHNAQKVYQVVLQNIVLSLIYNAILIPVAMLGYINPLIASLSMSGSSLLVVLNSLRLK 786
Query: 689 R 689
R
Sbjct: 787 R 787
>dbj|BAA07831.1| (D43776) P-type ATPase [Saccharomyces cerevisiae]
Length = 1232
Score = 185 bits (465), Expect = 1e-45
Identities = 142/544 (26%), Positives = 267/544 (48%), Gaps = 39/544 (7%)
Query: 142 FLIAVATIGAFLIKE-------YPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAE 194
++ ++ + G F++ + ++ ++G F+ ++A ++ +SI ++ +L+A
Sbjct: 653 YIFSIVSFGYFVVGRPLSTEQFFETSSLLVTLIMVGRFVSELARHRAVKSI-SVRSLQAS 711
Query: 195 YANLV-RDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTV 253
A LV + G ++ L+ GDI V P ++P DG +I G+S VD + +TGESMP
Sbjct: 712 SAILVDKTGKETEINIRLLQYGDIFKVLPDSRIPTDGTVISGSSEVDEALITGESMPVPK 771
Query: 254 KEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTP 313
K +++G +N TG L V++++ +T+S I +V+ A K K + + A Y+ P
Sbjct: 772 KCQSIVVAGSVNGTGTLFVKLSKLPGNNTISTIATMVDEAKLTKPKIQNIADKIASYFVP 831
Query: 314 AVVGIATLI----ATVPPLVFKESFTSWVYRALV----ILVISCPCALVLSIPLGYFGGI 365
++GI + V V K+S + V +A++ +L++SCPC + L++P+ +
Sbjct: 832 TIIGITVVTFCVWIAVGIRVEKQSRSDAVIQAIIYAITVLIVSCPCVIGLAVPIVFVIAS 891
Query: 366 GRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAAL 425
G AAK G++ K + ++ + S V FDKTGTLT+G V ET G L
Sbjct: 892 GVAAKRGVIFKSAESIEVAHNTSHVVFDKTGTLTEGKLTVVH-ETVRGDRHNSQSLLLGL 950
Query: 426 AEAHSNHPIAKAIREAYGKE--INEAEITEYEEIAGHGVR-ARIDSVEVMVGNDKLLHRS 482
E HP++ AI +Y KE ++ ++ + + G V +++ GN + L +
Sbjct: 951 TEG-IKHPVSMAI-ASYLKEKGVSAQNVSNTKAVTGKRVEGTSYSGLKLQGGNCRWLGHN 1008
Query: 483 NIEHDTCKVKG---TIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGD 539
N + D K ++ ++G + D ++ DA + L++ G+ + +++GD
Sbjct: 1009 N-DPDVRKALEQGYSVFCFSVNGSVTAVYALEDSLRADAVCTINLLRQRGI-SLHILSGD 1066
Query: 540 SRDVAEEIAKQLGLD--GFYAELLPEDKVKIIEKL--------EKEKGNGKLVFVGDGIN 589
+A +LG++ + P +K + I+ + + +VF GDG N
Sbjct: 1067 DDGAVRSMAARLGIESSNIRSHATPAEKSEYIKDIVEGRNCDSSSQSKRPVVVFCGDGTN 1126
Query: 590 DAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFAL 649
DA L +A +GV + GS+ A ADVV++ K + + I +++K V N +++
Sbjct: 1127 DAIGLTQATIGVHINE-GSEVAKLAADVVMLKPKLNNILTMITVSQKAMFRVKLNFLWSF 1185
Query: 650 GVKL 653
L
Sbjct: 1186 TYNL 1189
>gi|6319772 Putative P-type Cu(2+)-transporting ATPase; Pca1p [Saccharomyces
cerevisiae] >gi|584790|sp|P38360|ATU1_YEAST PROBABLE
COPPER-TRANSPORTING ATPASE (CU2+-ATPASE)
>gi|626795|pir||S46177 probable Ca2+-transporting ATPase
(EC 3.6.1.38) - yeast (Saccharomyces cerevisiae)
>gi|536754|emb|CAA85260.1| (Z36164) ORF YBR295w
[Saccharomyces cerevisiae] >gi|547580|emb|CAA82529.1|
(Z29332) cation transporting ATPase [Saccharomyces
cerevisiae]
Length = 1216
Score = 185 bits (464), Expect = 2e-45
Identities = 142/544 (26%), Positives = 267/544 (48%), Gaps = 39/544 (7%)
Query: 142 FLIAVATIGAFLIKE-------YPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAE 194
++ ++ + G F++ + ++ ++G F+ ++A ++ +SI ++ +L+A
Sbjct: 637 YIFSIVSFGYFVVGRPLSTEQFFETSSLLVTLIMVGRFVSELARHRAVKSI-SVRSLQAS 695
Query: 195 YANLV-RDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTV 253
A LV + G ++ L+ GDI V P ++P DG +I G+S VD + +TGESMP
Sbjct: 696 SAILVDKTGKETEINIRLLQYGDIFKVLPDSRIPTDGTVISGSSEVDEALITGESMPVPK 755
Query: 254 KEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTP 313
K +++G +N TG L V++++ +T+S I +V+ A K K + + A Y+ P
Sbjct: 756 KCQSIVVAGSVNGTGTLFVKLSKLPGNNTISTIATMVDEAKLTKPKIQNIADKIASYFVP 815
Query: 314 AVVGIATLI----ATVPPLVFKESFTSWVYRALV----ILVISCPCALVLSIPLGYFGGI 365
++GI + V V K+S + V +A++ +L++SCPC + L++P+ +
Sbjct: 816 TIIGITVVTFCVWIAVGIRVEKQSRSDAVIQAIIYAITVLIVSCPCVIGLAVPIVFVIAS 875
Query: 366 GRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAAL 425
G AAK G++ K + ++ + S V FDKTGTLT+G V ET G L
Sbjct: 876 GVAAKRGVIFKSAESIEVAHNTSHVVFDKTGTLTEGKLTVVH-ETVRGDRHNSQSLLLGL 934
Query: 426 AEAHSNHPIAKAIREAYGKE--INEAEITEYEEIAGHGVR-ARIDSVEVMVGNDKLLHRS 482
E HP++ AI +Y KE ++ ++ + + G V +++ GN + L +
Sbjct: 935 TEG-IKHPVSMAI-ASYLKEKGVSAQNVSNTKAVTGKRVEGTSYSGLKLQGGNCRWLGHN 992
Query: 483 NIEHDTCKVKG---TIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGD 539
N + D K ++ ++G + D ++ DA + L++ G+ + +++GD
Sbjct: 993 N-DPDVRKALEQGYSVFCFSVNGSVTAVYALEDSLRADAVSTINLLRQRGI-SLHILSGD 1050
Query: 540 SRDVAEEIAKQLGLD--GFYAELLPEDKVKIIEKL--------EKEKGNGKLVFVGDGIN 589
+A +LG++ + P +K + I+ + + +VF GDG N
Sbjct: 1051 DDGAVRSMAARLGIESSNIRSHATPAEKSEYIKDIVEGRNCDSSSQSKRPVVVFCGDGTN 1110
Query: 590 DAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFAL 649
DA L +A +GV + GS+ A ADVV++ K + + I +++K V N +++
Sbjct: 1111 DAIGLTQATIGVHINE-GSEVAKLAADVVMLKPKLNNILTMITVSQKAMFRVKLNFLWSF 1169
Query: 650 GVKL 653
L
Sbjct: 1170 TYNL 1173
>dbj|BAA84774.1| (AB017790) ATPase 7B [Rattus norvegicus]
Length = 1124
Score = 182 bits (458), Expect = 9e-45
Identities = 155/561 (27%), Positives = 262/561 (46%), Gaps = 85/561 (15%)
Query: 5 KLKLEGLDCASCAYEIEEAL-RKEGFKFAVVNFATKEAIIEGDIE--KAKEVIKKVEPDV 61
+L + G+ CASC + IE L R G +A V AT +A ++ D E +++IK +E
Sbjct: 559 ELIITGMTCASCVHNIESKLTRTNGITYASVALATSKAHVKFDPEIIGPRDIIKVIEEIG 618
Query: 62 EVVEEVHIHDHAHGEFEKRTI----------YFIGISLVLFTIGILM-----RYYYAIDN 106
H + +AH K I GI ++ I +L+ +D+
Sbjct: 619 FHASLAHRNPNAHHLDHKTEIKQWKKSFLCSLVFGIPVMGLMIYMLIPSSKPHETMVLDH 678
Query: 107 TLVFGLFLASYL----------ISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAF---- 152
++ GL + + + + GW A SL + + LI +AT A+
Sbjct: 679 NIIPGLSVLNLIFFILCTFVQFLGGWYFYVQA-YKSLRHKSANMDVLIVLATTIAYAYSL 737
Query: 153 -----LIKEYPEGVAV---------MLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANL 198
I E E V +F +G +L+ +A K+ ++ L++L+A A +
Sbjct: 738 VILVVAIAEKAEKSPVTFFDTPPMLFVFIALGRWLEHVAKSKTSEALAKLMSLQATEATV 797
Query: 199 V---RDGTVVK---VKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRT 252
V D +++ V E ++ GDII V PG K PVDG ++EG + D S +TGE+MP T
Sbjct: 798 VTLGEDNLILREEQVPMELVQRGDIIKVVPGGKFPVDGKVLEGNTMADESLITGEAMPVT 857
Query: 253 VKEGDEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYT 312
K G +++G IN G + ++ T +++T+++I++LVE A KA ++ RF+ Y+
Sbjct: 858 KKPGSIVIAGSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGYFV 917
Query: 313 PAVVGIATLIATVPPLVFKESF----------------TSWVYR-----ALVILVISCPC 351
P ++ I+TL V ++ F T + R ++ +L I+CPC
Sbjct: 918 PFIIIISTLTLVVWIIIGFVDFGIVQKYFPSPSKHISQTEVIIRFAFQTSITVLCIACPC 977
Query: 352 ALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTK---I 408
+L L+ P G G AA+ G+LIKG L+ V FDKTGT+T GV +V + +
Sbjct: 978 SLGLATPTAVMVGTGVAAQNGVLIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRFLLL 1037
Query: 409 ETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKEINEAEI---TEYEEIAGHGVRAR 465
+ ++L AEA S HP+ A+ + +E+ + T+++ + G G+ +
Sbjct: 1038 VDVATLSLRKVLAVVGTAEASSEHPLGVAVTKYCKEELGTETLGYSTDFQAVPGCGISCK 1097
Query: 466 IDSVEVMVGNDKLLHRSNIEH 486
+ +VE + L HR H
Sbjct: 1098 VSNVESI-----LAHRGPTAH 1113
>pir||A64453 H+-transporting ATPase (EC 3.6.1.35) - Methanococcus jannaschii
>gi|1591857|gb|AAB99229.1| (U67563) plasma membrane
ATPase 1 (aha1) [Methanococcus jannaschii]
Length = 805
Score = 178 bits (448), Expect = 1e-43
Identities = 185/624 (29%), Positives = 289/624 (45%), Gaps = 97/624 (15%)
Query: 142 FLIAVATIGAFLIKEYPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRD 201
++I +A I + +IK + + V +++ ++ + K+ I+ L A A ++RD
Sbjct: 61 WMIEIAAILSAIIKHWVDFVIILILLLVNGVVGFWEEYKAENVIEFLKQKMALNARVLRD 120
Query: 202 GTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTSSV-DTSALTGESMPRTVKEGDEIL 260
G + +EL GD++ ++ G+ VP D ++++G V D SALTGES+P K GD
Sbjct: 121 GKWQIIPAKELVPGDVVRIRIGDIVPADIILVDGDYLVVDESALTGESLPVEKKIGDIAY 180
Query: 261 SGMI----NLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTP-AV 315
SG I +TG++K TV +LVE A + + +K I + Y AV
Sbjct: 181 SGSIVKKGEMTGIVKATGLNTYFGKTV----KLVEKAE-KVSSYQKMIIKIGDYLIVLAV 235
Query: 316 VGIATLIATVPPLVFKESFTSWVYRALVILVISCPCAL--VLSIPLGYFGGIGRAAKEGI 373
+ IA ++A L +S ALV+ V + P A+ VLSI + G AK+
Sbjct: 236 ILIAIMVAV--ELFRGKSLIETAQFALVLAVSAIPAAMPAVLSITMAI--GALNLAKKDA 291
Query: 374 LIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALA------- 426
++K ++ L I+ DKTGTLTK +I NGF++E+++ FAALA
Sbjct: 292 IVKKLVAIEELAGVDILCSDKTGTLTKNQLVCGEIIALNGFSKEDVVLFAALASREEDAD 351
Query: 427 ----------------EAHSNHPIAKAIREAYGKEINEAEITEYEEIAGHGVRARIDSVE 470
E N+ I K I + EAE+T EE ++ +
Sbjct: 352 AIDMAILNEAKKLGLMEKIKNYKIKKFIPFDPVIKRTEAEVTNDEEFKVSKGAPQV--IL 409
Query: 471 VMVGNDKLLHR------SNIEHDTCKVKGTIAHVVIDGQYAGYIVISDEIKEDAHLAVKE 524
+ D+ L R + + + G + +AG I + D +EDA LAVK+
Sbjct: 410 DLCNADEELRRKVEEIVDKLAENGYRALGVAVYKNGRWHFAGIIPLYDPPREDAPLAVKK 469
Query: 525 LKRLGVRKVVMVTGDSRDVAEEIAKQLGL------------------------------- 553
+K LGV + MVTGD +A+ IA+ LG+
Sbjct: 470 IKELGV-IIKMVTGDHVAIAKNIARMLGIGDKIISISELLKKLKRGEIKEEKFDEIVEEA 528
Query: 554 DGFYAELLPEDKVKIIEKLEKEKGNGKLV-FVGDGINDAPVLARADVGVAMGALGSDAAI 612
DGF AE+ PE K KI++ L+K G LV GDG+NDAP L +AD G+A+ + +DAA
Sbjct: 529 DGF-AEVFPEHKYKIVDSLQK---RGHLVAMTGDGVNDAPALKKADCGIAV-SNATDAAR 583
Query: 613 ETADVVIMDDKPSKLPKAIQIARKT-QRI-------VWENIIFALGVKLAFIGLGIFGKA 664
AD+V++ S + AIQ AR+ QR+ + E I V+L + LGI+
Sbjct: 584 AAADIVLLSPGISVIVDAIQEARRIFQRMESYVIYRITETIRILFFVELCILILGIYPIT 643
Query: 665 TMW---EAVFADVGVALIAVFNAM 685
+ A+ D+ + IA N +
Sbjct: 644 ALMIVLLAILNDIPILAIAYDNVV 667
>pir||G64707 cation-transporting ATPase, P-type - Helicobacter pylori (strain
26695) >gi|2314677|gb|AAD08539.1| (AE000648)
cation-transporting ATPase, P-type (copA) [Helicobacter
pylori 26695]
Length = 788
Score = 178 bits (446), Expect = 2e-43
Identities = 170/722 (23%), Positives = 320/722 (43%), Gaps = 58/722 (8%)
Query: 6 LKLEGLDCASCAYEIEEAL-RKEGFKFAVVNFATK--EAIIEGDIEKAKEVIKKVEPDVE 62
L LE C +C + ++ L R G K VNF T + + E + KE+I+K+E
Sbjct: 86 LLLEKTHCNACLWLNQKVLERLSGVKKVSVNFTTHHLQIVFEKSLNP-KEIIQKIESLGY 144
Query: 63 VVEEVHIHDHAHGEFEKRTIYFIGISLVLFTIGILM------------------RYYYAI 104
+ + ++ +++ Y + +S+ F LM Y +
Sbjct: 145 GAKIYNAQNYTLKAQKEQRSYLLTLSVGFFATMNLMFIAIAKYASYGGASYGGANYGAGM 204
Query: 105 DNTLVFGLFLASYLIS-------GWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEY 157
D + L L S +S G +K A NG V + ++ + AF+ Y
Sbjct: 205 DKLMQRNLDLVSLFLSLLVLVVVGRFFIKGAFYGLKNG-VLGMDLSVSFGALSAFVYSVY 263
Query: 158 P---------EGVAVMLFYVIG-EFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKV 207
E + +L V G +FL+ A + AL + + +V +G +
Sbjct: 264 AMLVSQETYFEASSTILTLVFGSKFLELKARLFANEKCLALESHEIHSVIVVENGKQTEK 323
Query: 208 KPEELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLT 267
P+++ +G ++ V G K+ +DGV++ +SVD S ++GE P + D IL G +N+
Sbjct: 324 HPKDVAIGSVVWVPSGAKIALDGVLLNN-ASVDASLISGEFKPLELGVNDPILGGYVNVG 382
Query: 268 GLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPP 327
+V+ S +S +LE ++ + K E + A ++ AV+ +A + +
Sbjct: 383 VPFSYQVSANFQNSRLSGLLETLKKSFLEKPLIESSANQIADIFSKAVLFLAFVSFLLWQ 442
Query: 328 LVFKESFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDA 387
+F + + +LVISCPCA L+ P+ IG I+ K + +L+ L
Sbjct: 443 FGLGGNFEKALMVCISVLVISCPCAFALATPIALV--IGVFKNPLIVFKEALFLETLAKV 500
Query: 388 SIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKEIN 447
+ DKTGTLT+ K ++ + + E + +L + + + ++ G E++
Sbjct: 501 KKIFIDKTGTLTQ---KEVLLKEKIIYEEFDGRLLKSLLKVREHLAHSAILKSLDGDEVS 557
Query: 448 EAEITEYEEIAGHGVRARIDSVEVMVGNDKLLHRSNIEHDTCKVKGTIAHVVIDGQYAGY 507
+I E HG++A + ++VG+ K L ++ + + +
Sbjct: 558 LEKI----EFFAHGLKASYQNETLLVGSLKFLGSMGVDIPMKESANIMVGFAKNETLCAL 613
Query: 508 IVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVK 567
++ + +K +A V+ L+ G+ ++ +++GD+ +E AK+LG+ ++A L PEDK +
Sbjct: 614 FILEERLKANAKEVVQALQNKGL-ELEILSGDNESSVKECAKKLGISNYHAHLTPEDKAQ 672
Query: 568 IIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKL 627
I + G VGDG NDA LA V++G S + D++++++ S L
Sbjct: 673 TISSYK-----GVCAMVGDGNNDA--LALKQASVSLGFEKSALSKSACDILLLEEDLSLL 725
Query: 628 PKAIQIARKTQRIVWENIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIAVFNAMRV 687
KA A+K ++V +NI+ +L I + + G A + +L+ V N++R+
Sbjct: 726 KKAFDNAQKVYQVVLQNIVLSLIYNAILIPVAMLGYINPLIASLSMSASSLLVVLNSLRL 785
Query: 688 LR 689
R
Sbjct: 786 KR 787
>gb|AAB05680.1| (U49498) Orf2; similar to Staphylococcus aureus SwissProt Accession
Number P20021 and to Bacillus firmus SwissProt Accession
Number P30336 [Legionella pneumophila]
Length = 389
Score = 152 bits (381), Expect = 1e-35
Identities = 90/271 (33%), Positives = 151/271 (55%), Gaps = 22/271 (8%)
Query: 109 VFGLF--LASYLI----SGWKVLKSAIVNSLNGN-------------VFDENFLIAVATI 149
VF LF LA+Y + S W ++ + + L+G+ + N L+ +A
Sbjct: 119 VFALFSELAAYFLGTEQSTWSIIPALLAMVLSGSPTFKKGWLALRTKAMNINSLMLIAIS 178
Query: 150 GAFLIKEYPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKP 209
GA LI E+PE V + + + E ++ ++DK+R +I++L+ + E A + D + P
Sbjct: 179 GAVLIGEWPEAAMVTVLFALAERIERYSLDKARLAIRSLMQIAPEVARVKMDNGQWQTMP 238
Query: 210 -EELKVGDIIIVKPGEKVPVDGVIIEGTSSVDTSALTGESMPRTVKEGDEILSGMINLTG 268
EE+ + + V+PGE++P+DGV+I G S+V+ + +TGESMP V GDE+ +G +N G
Sbjct: 239 VEEVPLEAVFRVRPGERIPLDGVVISGQSTVNQAPITGESMP-VVNRGDEVFAGSLNELG 297
Query: 269 LLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPL 328
+V+VT+ ++ +++I + +E A A + + T P+ LIA PPL
Sbjct: 298 AFEVQVTKASGDTLLAKIGKAIEQAQAERRQLNVLWTNLPSITHPSW-SYRILIALFPPL 356
Query: 329 VFKESFTSWVYRALVILVISCPCALVLSIPL 359
F W+Y+AL +LVI+CPCALV+S P+
Sbjct: 357 ALGYPFYDWLYKALTLLVIACPCALVISTPV 387
>gb|AAB06958.1| (U65004) P-type proton motive membrane ATPase [Pneumocystis
carinii]
Length = 927
Score = 147 bits (368), Expect = 3e-34
Identities = 166/628 (26%), Positives = 271/628 (42%), Gaps = 97/628 (15%)
Query: 142 FLIAVATIGAFLIKEYPE-GV--AVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANL 198
F++ A I A ++++ + GV A++L F+Q+ +K LALKA +
Sbjct: 127 FVMEAAAILAASLQDWVDFGVICALLLLNAFVGFIQEFQAGSIVDELKKTLALKA---TV 183
Query: 199 VRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVII--EGTSSVDTSALTGESMPRTVKEG 256
+RDG ++ ++ EE+ GDI+ ++ G VP DG I+ E VD S++TGES+ +G
Sbjct: 184 LRDGRLIDIEAEEVVPGDILQLEEGSIVPADGRIVTEEAYIQVDQSSITGESLAVDKHKG 243
Query: 257 DEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVV 316
D I S + G + VT + V LV AS + R VV
Sbjct: 244 DNIYSSSVVKRGETFMVVTATGDGTFVGHAASLVNKASCGTGHFTDVLNRIGTILLVLVV 303
Query: 317 GIATLIATVPPLVFKESFTSWVYR-ALVILVISCPCALVLSIPLGYFGGIGRAAKEGILI 375
TL ++ S T + + L I +I P L + G AK+ ++
Sbjct: 304 --FTLFVVYISAFYRSSTTITILKYTLAITIIGVPVGLPAVVTTTMAVGAAYLAKKKAIV 361
Query: 376 KGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIA 435
+ + +++L I+ DKTGTLTK + + T G + +E++ A LA + +
Sbjct: 362 QKLSAIESLAGVEILCSDKTGTLTKNDLSLAEPYTVEGISCDELMLTACLAASRKKKGL- 420
Query: 436 KAIREAYGKEIN-----EAEITEYEEIAGH-------GVRARIDSVE----VMVGNDKLL 479
AI +A+ K + + I++Y + H V A ++S V L
Sbjct: 421 DAIDKAFLKALRNYPVVRSAISKYNLVEFHPFDPVSKKVTAIVESPSGERIACVKGAPLF 480
Query: 480 HRSNIEHD-------TCKVKGTIAHVVIDG---------------QYAGYIVISDEIKED 517
+E D K +A G + G + SD + D
Sbjct: 481 VLRTVEEDQPVPEDIQNAYKDKVAEFASRGYRSLGIARKTGNSNWEILGIMPCSDPPRCD 540
Query: 518 AHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGL------------------------ 553
+ E RLG+R + M+TGD+ +A+E A+QLG+
Sbjct: 541 TARTISEAIRLGLR-IKMLTGDAVGIAKETARQLGMGTNVYNAERLGLGGGGDMPGSEVY 599
Query: 554 ------DGFYAELLPEDKVKIIEKLEKEKGNGKLV-FVGDGINDAPVLARADVGVAMGAL 606
DGF AE+ P+ K ++E L++ G LV GDG+NDAP L +AD G+A+
Sbjct: 600 DFVEAADGF-AEVFPQHKYNVVEILQQ---RGYLVAMTGDGVNDAPSLKKADTGIAVEG- 654
Query: 607 GSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKL---AFIGLG--IF 661
SDAA AD+V + S + A++ +R+ ++ +++ + + L F+GL IF
Sbjct: 655 ASDAARSAADIVFLAPGLSAIIDALKTSRQIFHRMYAYVVYRIALSLHLEIFLGLWIVIF 714
Query: 662 GKATMWE-----AVFADVGVALIAVFNA 684
+ E A+FAD+ IA NA
Sbjct: 715 NHLMILELVVFIAIFADIATLAIAYDNA 742
>sp|Q07421|PMA1_AJECA PLASMA MEMBRANE ATPASE (PROTON PUMP) >gi|409249|gb|AAB53772.1|
(L07305) ATPase [Ajellomyces capsulatus]
>gi|740012|prf||2004293A H ATPase [Ajellomyces
capsulatus]
Length = 916
Score = 139 bits (348), Expect = 7e-32
Identities = 159/637 (24%), Positives = 274/637 (42%), Gaps = 115/637 (18%)
Query: 142 FLIAVATIGAFLIKEYPE-GV--AVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANL 198
F++ A I A ++++ + GV A++L F+Q+ +K LALKA +
Sbjct: 122 FVMEAAAILAAGLEDWVDFGVICALLLLNACVGFVQEFQAGSIVDELKKTLALKAV---V 178
Query: 199 VRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGVII--EGTSSVDTSALTGESMPRTVKEG 256
+R+G + +V+ E+ GDI+ V+ G +P DG I+ E VD SA+TGES+ +G
Sbjct: 179 LRNGRLTEVEAPEVVPGDILQVEEGTIIPADGRIVTEEAFLQVDQSAITGESLAVDKHKG 238
Query: 257 DEILSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVV 316
D + G + +T + V R LV ASA ++T +
Sbjct: 239 DTCYASSAVKRGEAFMVITATGDNTFVGRGPALVNAASAGTG-----------HFTEVLN 287
Query: 317 GIATLIATVPPLVFKESFTSWVYRA----------LVILVISCPCALVLSIPLGYFGGIG 366
GI T++ + L + S YR+ L I +I P L + G
Sbjct: 288 GIGTVLLILVILTLLVVWVSSFYRSNSIVTILEFTLAITIIGVPVGLPAVVTTTMAVGAA 347
Query: 367 RAAKEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALA 426
AK+ +++ + +++L I+ DKTGTLTK + + +G E+++ A LA
Sbjct: 348 YLAKKKAIVQKLSAIESLAGVEILCSDKTGTLTKNKLSLAEPYCVSGVDPEDLMLTACLA 407
Query: 427 EAHSNHPIAKAIREAYGKEIN-----EAEITEYEEIAGH---GVRARIDSVEVMVGNDK- 477
+ I AI +A+ K + ++ +T+Y+ + H V ++ +V + ++
Sbjct: 408 ASRKKKGI-DAIDKAFLKSLRYYPRAKSVLTQYKVLEFHPFDPVSKKVSAVVLSPQGERI 466
Query: 478 -------LLHRSNIEHD-------TCKVKGTIAHVVIDG---------------QYAGYI 508
L +E D K +A G + G +
Sbjct: 467 TCVKGAPLSVLKTVEEDHPIPDEVDSAYKNKVAEFATRGFRSLGVARKRGEGSWEILGIM 526
Query: 509 VISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGL--------------- 553
SD + D + E K LG+ + M+TGD+ +A E ++QLGL
Sbjct: 527 PCSDPPRHDTAKTINEAKTLGL-SIKMLTGDAVGIARETSRQLGLGTNVYNAERLGLGGG 585
Query: 554 ---------------DGFYAELLPEDKVKIIEKLEKEKGNGKLV-FVGDGINDAPVLARA 597
DGF AE+ P+ K ++E L++ G LV GDG+NDAP L +A
Sbjct: 586 GTMPGSEVYDFVEAADGF-AEVFPQHKYNVVEILQQ---RGYLVAMTGDGVNDAPSLKKA 641
Query: 598 DVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFA--------- 648
D G+A+ SDAA AD+V + S + A++ +R+ ++ +++
Sbjct: 642 DTGIAVEG-ASDAARSAADIVFLAPGLSAIIDALKTSRQIFHRMYAYVVYRIALSLHLEI 700
Query: 649 -LGVKLAFIGLGIFGKATMWEAVFADVGVALIAVFNA 684
LG+ +A + + + ++ A+FAD+ IA NA
Sbjct: 701 FLGLWIAILNTSLNLQLVVFIAIFADIATLAIAYDNA 737
>emb|CAB40585.1| (AJ010131) ykvW [Bacillus cereus]
Length = 225
Score = 137 bits (342), Expect = 4e-31
Identities = 75/217 (34%), Positives = 129/217 (58%), Gaps = 4/217 (1%)
Query: 473 VGNDKLLHRSNIEHDTCKVKGTIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRK 532
+G + + I K T+ ++ + G I + D ++++ A++EL+ +GV +
Sbjct: 10 IGEETKTFHNGISASLEKEGKTVVYISDEDGILGLIALKDTLRQETIAAIRELQSIGV-E 68
Query: 533 VVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAP 592
+M+TGD+ + A+ IA + + +YA LPE KV+ I+KL+++ G + VGDGINDAP
Sbjct: 69 AIMITGDNEETAKAIASESNIKEYYASCLPETKVETIKKLKEKYGT--VAMVGDGINDAP 126
Query: 593 VLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVK 652
LA A +GVAMG G+D A+ETADVV+M ++ S+L +AI+++++ RIV +N+IF+L V
Sbjct: 127 ALATASIGVAMGE-GTDVALETADVVLMKNELSRLSQAIRLSKRMNRIVKQNVIFSLAVI 185
Query: 653 LAFIGLGIFGKATMWEAVFADVGVALIAVFNAMRVLR 689
I + V G ++ + N +R+L+
Sbjct: 186 AMLICSNFLQFLALPFGVIGHEGSTILVILNGLRLLK 222
>sp|P49380|PMA1_KLULA PLASMA MEMBRANE ATPASE (PROTON PUMP) >gi|598435|gb|AAA69688.1|
(L37875) proton-ATPase [Kluyveromyces lactis]
Length = 899
Score = 134 bits (335), Expect = 2e-30
Identities = 154/607 (25%), Positives = 263/607 (42%), Gaps = 116/607 (19%)
Query: 169 IGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIVKPGEKVPV 228
I E+ VD+ ++++ A A ++RDG +V+V E+ GDI+ ++ G +P
Sbjct: 141 IQEYQAGSIVDELKKTL-------ANSAVVIRDGNLVEVPSNEVVPGDILQLEDGVVIPA 193
Query: 229 DGVIIEGTS--SVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRVTRELSESTVSRI 286
DG ++ +D SA+TGES+ + GD S G + VT + V R
Sbjct: 194 DGRLVTEDCFIQIDQSAITGESLAVDKRFGDSTFSSSTVKRGEAFMIVTATGDSTFVGRA 253
Query: 287 LELVENASARKAKTEKFITRFAHYYTPAVVGIAT----LIATVPPLVFKESF--TSWVYR 340
LV A+A ++T + GI T L+ LV+ SF T+ + R
Sbjct: 254 AALVNKAAAGSG-----------HFTEVLNGIGTILLILVIVTLLLVWVASFYRTNKIVR 302
Query: 341 ----ALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTG 396
L I ++ P L + G AK+ +++ + +++L I+ DKTG
Sbjct: 303 ILRYTLAITIVGVPVGLPAVVTTTMAVGAAYLAKKQAIVQKLSAIESLAGVEILCSDKTG 362
Query: 397 TLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKEI-----NEAEI 451
TLTK + + T G ++++ A LA + + AI +A+ K + +A +
Sbjct: 363 TLTKNKLSLHEPYTVEGVDPDDLMLTACLAASRKKKGL-DAIDKAFLKSLISYPRAKAAL 421
Query: 452 TEYEEIAGH-------GVRARIDSVE----VMVGNDKLLHRSNIEHD-------TCKVKG 493
T+Y+ + H V A ++S E + V L +E + +
Sbjct: 422 TKYKLLEFHPFDPVSKKVTAIVESPEGERIICVKGAPLFVLKTVEEEHPIPEDVRENYEN 481
Query: 494 TIAHVVIDG---------------QYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTG 538
+A + G + G + D ++D V E + LG+R V M+TG
Sbjct: 482 KVAELASRGFRALGVARKRGEGHWEILGVMPCMDPPRDDTAQTVNEARHLGLR-VKMLTG 540
Query: 539 DSRDVAEEIAKQLGL------------------------------DGFYAELLPEDKVKI 568
D+ +A+E +QLGL DGF AE+ P+ K +
Sbjct: 541 DAVGIAKETCRQLGLGTNIYNAERLGLGGGGDMPGSELADFVENADGF-AEVFPQHKYNV 599
Query: 569 IEKLEKEKGNGKLV-FVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKL 627
+E L++ G LV GDG+NDAP L +AD G+A+ +DAA AD+V + S +
Sbjct: 600 VEILQQ---RGYLVAMTGDGVNDAPSLKKADTGIAVEG-ATDAARSAADIVFLAPGLSAI 655
Query: 628 PKAIQIARKTQRIVWENIIFALGVKL---AFIGL--GIFGKA-----TMWEAVFADVGVA 677
A++ +R+ ++ +++ + + L F+GL I ++ ++ A+FADV
Sbjct: 656 IDALKTSRQIFHRMYSYVVYRIALSLHLEIFLGLWIAILNRSLNIDLVVFIAIFADVATL 715
Query: 678 LIAVFNA 684
IA NA
Sbjct: 716 AIAYDNA 722
>sp|Q08436|PMA3_NICPL PLASMA MEMBRANE ATPASE 3 (PROTON PUMP 3) >gi|170295|gb|AAA34098.1|
(M80490) plasma membrane H+ ATPase [Nicotiana
plumbaginifolia]
Length = 956
Score = 132 bits (330), Expect = 9e-30
Identities = 145/610 (23%), Positives = 261/610 (42%), Gaps = 100/610 (16%)
Query: 156 EYPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVG 215
++ + V ++ +I + + + + + AL+A A A ++RDG + L G
Sbjct: 96 DWQDFVGIITLLIINSTISFIEENNAGNAAAALMARLAPKAKVLRDGKWKEEDAAVLVPG 155
Query: 216 DIIIVKPGEKVPVDGVIIEGTS-SVDTSALTGESMPRTVKEGDEILSGMINLTGLLKVRV 274
DII +K G+ +P D ++EG +D SALTGES+P T GD + SG G ++ V
Sbjct: 156 DIISIKLGDIIPADARLLEGDPLKIDQSALTGESLPVTKGPGDGVYSGSTCKQGEIEAVV 215
Query: 275 TRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAV-VGIATLIATVPPLVFKES 333
+ + LV++ + + +K +T ++ ++ VG+ I + P+ ++
Sbjct: 216 IATGVHTFFGKAAHLVDSTN-QVGHFQKVLTAIGNFCICSIAVGMIIEIIVMYPIQHRK- 273
Query: 334 FTSWVYRALVILVISCPCAL--VLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVA 391
+ + LV+L+ P A+ VLS+ + G R A++G + K ++ + ++
Sbjct: 274 YRPGIDNLLVLLIGGIPIAMPTVLSVTMAI--GSHRLAQQGAITKRMTAIEEMAGMDVLC 331
Query: 392 FDKTGTLTKGVFKVTK--IET-RNGFTEEEILRFAALAEAHSNHPIAKA----------- 437
DKTGTLT V K IE G + ++ AA A N A
Sbjct: 332 SDKTGTLTLNKLTVDKYLIEVFARGVDADTVVLMAARASRTENQDAIDAAIVGMLADPKE 391
Query: 438 ----IREAYGKEINEAE-ITEYEEIAGHGVRARIDSVEVMVGNDKLLHRSNIEHDTCKVK 492
IRE + N + T + G G R+ +++LH + H+ ++
Sbjct: 392 ARAGIREIHFLPFNPTDKRTALTYLDGEGKMHRVSK----GAPEQILH---LAHNKSDIE 444
Query: 493 GTIAHVVID----------------------------GQYAGYIVISDEIKEDAHLAVKE 524
+ H VID Q+ + + D + D+ ++
Sbjct: 445 RRV-HAVIDKFAERGLRSLAVAYQEVPEGRKESAGGPWQFIALLPLFDPPRHDSAETIRR 503
Query: 525 LKRLGVRKVVMVTGDSRDVAEEIAKQLGL------------------------------- 553
LGV V M+TGD + +E ++LG+
Sbjct: 504 ALNLGV-NVKMITGDQLAIGKETGRRLGMGTNMYPSSALLGQTKDESISALPVDELIEKA 562
Query: 554 DGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPVLARADVGVAMGALGSDAAIE 613
DGF A + PE K +I+++L+ K + GDG+NDAP L +AD+G+A+ +DAA
Sbjct: 563 DGF-AGVFPEHKYEIVKRLQARKHICGM--TGDGVNDAPALKKADIGIAVDD-ATDAARS 618
Query: 614 TADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGLGIFGKATMWEAVFAD 673
+D+V+ + S + A+ +R + + I+A+ + + + LG A +W+ F
Sbjct: 619 ASDIVLTEPGLSVIISAVLTSRAIFQRMKNYTIYAVSITIRIV-LGFMLLALIWQFDFPP 677
Query: 674 VGVALIAVFN 683
V +IA+ N
Sbjct: 678 FMVLIIAILN 687
>sp|P54679|PMA1_DICDI PROBABLE PLASMA MEMBRANE ATPASE (PROTON PUMP) (PAT2)
>gi|7489894|pir||T30580 P-type ATPase - slime mold
(Dictyostelium discoideum) >gi|1370073|emb|CAA66931.1|
(X98286) P-type ATPase [Dictyostelium discoideum]
Length = 1058
Score = 132 bits (328), Expect = 2e-29
Identities = 151/636 (23%), Positives = 259/636 (39%), Gaps = 126/636 (19%)
Query: 141 NFLIAVATIGAFLIKEYPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVR 200
++ + VA I + + ++ + + + ++ + + + + +++AL +R
Sbjct: 221 SWTMEVAAIVSIALLDWVDFILICALLLLNATIGFIEENTAGNAVEALKNSLVSQIRCMR 280
Query: 201 DGTVVKVKPEELKVGDIIIVKPGEKVPVDGVIIEGTS-SVDTSALTGESMPRTVKEGDEI 259
DG V + +L GD++++K G +P D +IE +D S+LTGES+P T K GDE+
Sbjct: 281 DGEWVMLPSPDLVPGDVVMLKIGAIIPADCRVIEAEQVKIDQSSLTGESLPVTKKIGDEV 340
Query: 260 LSGMINLTGLLKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIA 319
SG G K VT + R LV+ + I R + + + I
Sbjct: 341 YSGSAMKQGEAKCVVTATGVNTFFGRAANLVQETEGHGHL--QVILRNIGLFCISFIAIW 398
Query: 320 TLIATVPPLVFKESFTSWV--------YRALVILVISCPCAL--VLSIPLGYFGGIGRAA 369
L+ + + + + V ALV+LV P A+ VLS+ + G + +
Sbjct: 399 VLVELLVDFLGYDGYCHGVGGGRCLPLNNALVLLVGGIPIAMPTVLSVTMAI--GATQLS 456
Query: 370 KEGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKIETRNGFTEEEIL--RFAALAE 427
K+ ++ ++ L I+ DKTGTLT + V + +E+I+ F A +E
Sbjct: 457 KKKAIVSRLASIEELAAMDILCSDKTGTLTLNILTVDEPLPVGDTPKEDIVFHAFLACSE 516
Query: 428 A--------------------------------HSNHPIAKA------------------ 437
A HS I K
Sbjct: 517 AKTKMQSIRQSQTIVVIPIQMLTTLVMKSLNITHSTQKIKKQWVFVNANGKQFKTAKGAP 576
Query: 438 ---IREAYG-KEINEAEITEYEEIAGHGVRARIDSVEVMVGNDKLLHRSNIEHDTCKVKG 493
+REA K++ EA E E +A G RA SV + K+ H
Sbjct: 577 QIILREADNYKQVGEAVEKEIENLADRGYRALGVSVSYDAPDFKVWH------------- 623
Query: 494 TIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGL 553
+ G I + D + D +K +GV V M+TGD +A+E A++LG+
Sbjct: 624 ----------FEGLIPLFDPPRHDTEDTIKRALEMGV-SVKMITGDQLAIAKETARRLGM 672
Query: 554 DGF-------------------------YAELLPEDKVKIIEKLEKEKGNGKLVFVGDGI 588
G +AE+ PE K K++++L+K K + GDG+
Sbjct: 673 GGNLFTIPYLENNDLGISEGEVIEMADGFAEMWPEHKYKVVDQLQKRKH--VVGMTGDGV 730
Query: 589 NDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFA 648
NDAP L +A +G+A+ A +DAA +D+V+ S + AI +RK + + +I++
Sbjct: 731 NDAPALKKAQIGIAV-AGATDAARSVSDIVLTSSGLSVIIDAIISSRKIFQRMRNYVIYS 789
Query: 649 LGVKLAFIGLGIFGKATM-WEAVFADVGVALIAVFN 683
+ + FG T+ W F + +IA+ N
Sbjct: 790 VAATVRI--CTTFGILTVAWNFKFPTIATVIIAILN 823
>sp|P09627|PMA1_SCHPO PLASMA MEMBRANE ATPASE 1 (PROTON PUMP 1) >gi|67968|pir||PXZP1P
H+-transporting ATPase (EC 3.6.1.35) 1, plasma membrane
- fission yeast (Schizosaccharomyces pombe)
>gi|173429|gb|AAA35324.1| (J03498) H+-ATPase
[Schizosaccharomyces pombe] >gi|6179667|emb|CAB59886.1|
(AL132769) plasma membrane atpase 1 (EC 3.6.1.35)
[Schizosaccharomyces pombe]
Length = 919
Score = 131 bits (326), Expect = 3e-29
Identities = 155/615 (25%), Positives = 269/615 (43%), Gaps = 117/615 (19%)
Query: 163 VMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIVKP 222
+ML V+G F+Q+ +K LALKA ++R+G V +++ E+ GDI+ +
Sbjct: 149 LMLNAVVG-FVQEYQAGSIVDELKKSLALKAV---VIREGQVHELEANEVVPGDILKLDE 204
Query: 223 GEKVPVDGVII--EGTSSVDTSALTGESMPRTVKEGDEIL--SGMINLTGLLKVRVTREL 278
G + DG ++ + VD SA+TGES+ GD SG+ GL+ V T +
Sbjct: 205 GTIICADGRVVTPDVHLQVDQSAITGESLAVDKHYGDPTFASSGVKRGEGLMVVTATGD- 263
Query: 279 SESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFKESFTSWV 338
+ V R LV A+ ++T + GI T++ + L +T+
Sbjct: 264 -STFVGRAASLVNAAAGGTG-----------HFTEVLNGIGTILLVLVLLTLFCIYTAAF 311
Query: 339 YRA----------LVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDAS 388
YR+ L I +I P L + G A++ +++ + +++L
Sbjct: 312 YRSVRLARLLEYTLAITIIGVPVGLPAVVTTTMAVGAAYLAEKQAIVQKLSAIESLAGVE 371
Query: 389 IVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAALAEAHSNHPIAKAIREAYGKEINE 448
++ DKTGTLTK + + T +G + ++++ A LA + + AI +A+ K +
Sbjct: 372 VLCSDKTGTLTKNKLSLGEPFTVSGVSGDDLVLTACLAASRKRKGL-DAIDKAFLKALKN 430
Query: 449 -----AEITEYEEI-------AGHGVRARIDSVE----VMVGNDKLLHRSNIEHD----- 487
+ +T+Y+ I V A + + + V L +E D
Sbjct: 431 YPGPRSMLTKYKVIEFQPFDPVSKKVTAYVQAPDGTRITCVKGAPLWVLKTVEEDHPIPE 490
Query: 488 --TCKVKGTIAHVV------------IDGQY---AGYIVISDEIKEDAHLAVKELKRLGV 530
K + + I+GQ+ G + SD + D + E KRLG+
Sbjct: 491 DVLSAYKDKVGDLASRGYRSLGVARKIEGQHWEIMGIMPCSDPPRHDTARTISEAKRLGL 550
Query: 531 RKVVMVTGDSRDVAEEIAKQLGL------------------------------DGFYAEL 560
R V M+TGD+ D+A+E A+QLG+ DGF E+
Sbjct: 551 R-VKMLTGDAVDIAKETARQLGMGTNIYNAERLGLTGGGNMPGSEVYDFVEAADGF-GEV 608
Query: 561 LPEDKVKIIEKLEKEKGNGKLV-FVGDGINDAPVLARADVGVAMGALGSDAAIETADVVI 619
P+ K +++ L++ G LV GDG+NDAP L +AD G+A+ +DAA AD+V
Sbjct: 609 FPQHKYAVVDILQQR---GYLVAMTGDGVNDAPSLKKADTGIAVEG-ATDAARSAADIVF 664
Query: 620 MDDKPSKLPKAIQIARKTQRIVWENIIFALGVKL---AFIGLGIFGK-------ATMWEA 669
+ S + A++ +R+ ++ +++ + + L F+GL + + ++ A
Sbjct: 665 LAPGLSAIIDALKTSRQIFHRMYSYVVYRIALSLHLEIFLGLWLIIRNQLLNLELVVFIA 724
Query: 670 VFADVGVALIAVFNA 684
+FADV IA NA
Sbjct: 725 IFADVATLAIAYDNA 739
>pir||T05728 probable cadmium-transporting ATPase - soybean
>gi|2565259|gb|AAB81947.1| (AF019115) putative
cadmium-transporting ATPase [Glycine max]
Length = 329
Score = 120 bits (297), Expect = 7e-26
Identities = 79/284 (27%), Positives = 137/284 (47%), Gaps = 23/284 (8%)
Query: 427 EAHSNHPIAKAIRE-AYGKEINEAEITEYEEIAGHGVRARIDSVEVMVGNDKLLHRS--- 482
E + HPI +A+ + + GK++ + +E G G+ A ++S+E G KLL S
Sbjct: 2 EKGTTHPIGRAVVDHSEGKDLPSISVESFEYFPGRGLTATVNSIESGTGGAKLLKASLGS 61
Query: 483 --------NIEHDTCKVKGTI---------AHVVID-GQYAGYIVISDEIKEDAHLAVKE 524
E ++ K+K + H + Q I + D + ++E
Sbjct: 62 IDFITSFCQSEVESEKIKEAVNTSSYGSEYVHAALSVNQKVTLIHLEDRPRPGVSNVIQE 121
Query: 525 LKRLGVRKVVMVTGDSRDVAEEIAKQLGLDGFYAELLPEDKVKIIEKLEKEKGNGKLVFV 584
L+ +V+M+TGD A +A +G++ F+ L PEDK+ ++ + ++ G G L+ V
Sbjct: 122 LQDEAKFRVMMLTGDHESSARRVASAVGINEFHCNLKPEDKLSHVKDISRDMGGG-LIMV 180
Query: 585 GDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWEN 644
G+GINDAP LA A VG+ + S AI ADV+++ + S +P I +R+T ++ +N
Sbjct: 181 GEGINDAPALAAATVGIVLAHRASATAIAVADVLLLRENISAVPFCIAKSRQTTSLIKQN 240
Query: 645 IIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIAVFNAMRVL 688
+ AL + + G +W V G L+ N++R L
Sbjct: 241 VALALTSIVMASLPSVLGFLPLWLTVLLHEGGTLLVCLNSVRAL 284
>gi|11497808 A. fulgidus predicted coding region AF0191 [Archaeoglobus fulgidus]
>gi|7483382|pir||G69273 hypothetical protein AF0191 -
Archaeoglobus fulgidus >gi|2650466|gb|AAB91053.1|
(AE001093) A. fulgidus predicted coding region AF0191
[Archaeoglobus fulgidus]
Length = 86
Score = 118 bits (292), Expect = 3e-25
Identities = 59/87 (67%), Positives = 72/87 (81%), Gaps = 1/87 (1%)
Query: 603 MGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVKLAFIGLGIFG 662
MGA+ S AAIE DVVIMDD+PSK+ +AI++A++TQ++VWENI+ AL VK FI LG G
Sbjct: 1 MGAMRS-AAIEVVDVVIMDDRPSKVARAIRLAKRTQKVVWENIVLALAVKGFFISLGAMG 59
Query: 663 KATMWEAVFADVGVALIAVFNAMRVLR 689
ATMWEAVFADVGV LIAV N+MR+LR
Sbjct: 60 MATMWEAVFADVGVTLIAVMNSMRLLR 86
>sp|P07893|ATSY_SYNP6 PROBABLE COPPER-TRANSPORTING ATPASE SYNA >gi|79650|pir||S10839
hypothetical protein 5 - Synechococcus sp. (PCC 6301)
(fragment) >gi|48026|emb|CAA29364.1| (X05925) VRF 5 (293
AA) [Synechococcus PCC6301]
Length = 293
Score = 105 bits (260), Expect = 1e-21
Identities = 82/283 (28%), Positives = 144/283 (49%), Gaps = 15/283 (5%)
Query: 417 EEILRFAALAEAHSNHPIAKAIREAYGKEINEAEI--TEYEEIAGHGVRARIDSVEVMVG 474
+ +L++AA EA S HP+A A++ A + N A I ++ +++ G GV D + +G
Sbjct: 3 DRLLQWAAALEADSRHPLATALQTA-AQAANLAPIAASDRQQVPGLGVSGTCDGRSLRLG 61
Query: 475 NDKLLHRSNIEHDTCKVKGTIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVV 534
N + + + T T + D Q + D+ + +A V+ L+ G V
Sbjct: 62 NPTWVQVATAKLPTGSAAATSIWLADDQQLLACFWLQDQPRPEAAEVVQALRSRGAT-VQ 120
Query: 535 MVTGDSRDVAEEIAKQLGLDG--FYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAP 592
+++GD + A +A+QLGL+ AE+LPEDK I L+ + + +GDGINDAP
Sbjct: 121 ILSGDRQTTAVALAQQLGLESETVVAEVLPEDKAAAIAALQSQ--GDAVAMIGDGINDAP 178
Query: 593 VLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKTQRIVWENIIFALGVK 652
LA A VG+++ A GSD A ++A +++ D+ + A +++ R + +N+ +ALG
Sbjct: 179 ALATAAVGISLAA-GSDIAQDSAGLLLSRDRLDSVLVAWNLSQMGLRTIRQNLTWALGYN 237
Query: 653 LAFIGLG------IFGKATMWEAVFADVGVALIAVFNAMRVLR 689
+ + L +G A A + V+ +AV + +LR
Sbjct: 238 VVMLPLAAGAFLPAYGLALTPAIAGACMAVSSLAVVSNSLLLR 280
>pir||T31853 hypothetical protein C02E7.1 - Caenorhabditis elegans
>gi|2315419|gb|AAC24161.1| (AF016446) strong similarity
to the cation transport ATPase family (E1-E2 ATPases)
[Caenorhabditis elegans]
Length = 1050
Score = 88.5 bits (216), Expect = 2e-16
Identities = 81/318 (25%), Positives = 150/318 (46%), Gaps = 26/318 (8%)
Query: 112 LFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEYPEGVAVMLFYVIGE 171
LFL + W ++ A SL ++D + L + +G F+I V + + ++
Sbjct: 95 LFLRQFKNLLWILMFGAAALSLVAYIYDPSDLTNLC-VGIFII------VIIFVMCIVSF 147
Query: 172 FLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIVKPGEKVPVDGV 231
F + V+ R + ++L+ L + ++RDG + PEEL VGDI++V+ G KVP D
Sbjct: 148 FEEKKGVEVVR-AFQSLMPLSCQ---VIRDGVEQTLNPEELVVGDIVVVRSGCKVPADIR 203
Query: 232 IIEGTS-SVDTSALTGESMP-----------RTVKEGDEI-LSGMINLTGLLKVRVTREL 278
+I T ++TS++TGE+ P ++ E I +G + G V R
Sbjct: 204 VIACTDFYLETSSITGEAEPLEFNSAMADQKTSIFESYNIAFNGSFCVDGEGYGIVIRTG 263
Query: 279 SESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVPPLVFK--ESFTS 336
+ + +I + + +K K + I RF + T + +A +I +V + K +
Sbjct: 264 ERTVIGQIASMTLDQKEQKCKFQVEIGRFVKFITVMAIIMAVIIFSVGLGINKGHDVIRY 323
Query: 337 WVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDASIVAFDKTG 396
+V L++++ + P L ++ R AK+ + +K +D++ +++A DKTG
Sbjct: 324 FVTGFLMVIIANVPQGLPTTVTTELTIIARRMAKKNVFLKKLEKIDSVGATTLIASDKTG 383
Query: 397 TLTKGVFKVTKIETRNGF 414
TLTK VT + N +
Sbjct: 384 TLTKNCMTVTDLWYNNSY 401
>dbj|BAA75381.1| (AB013371) YkvW [Bacillus halodurans]
Length = 185
Score = 84.3 bits (205), Expect = 4e-15
Identities = 44/140 (31%), Positives = 84/140 (59%), Gaps = 1/140 (0%)
Query: 87 ISLVLFTIGILMRYYYAIDNTLVFGLFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAV 146
+S +L +G++ + + LF +S +I G+ + K+ N + FD L+ V
Sbjct: 47 VSALLLLVGVVSYFMKGERHLWTVSLFASSIVIGGYSLFKAGFYNLIRLR-FDMKTLMTV 105
Query: 147 ATIGAFLIKEYPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVK 206
A IGA LI E+ EG V++ + I E L+ ++D++R+SI++L+ + + A + R+G +
Sbjct: 106 AVIGAALIGEWLEGAVVVILFAISEALERFSMDRARQSIRSLVDMAPKEALVRRNGEELV 165
Query: 207 VKPEELKVGDIIIVKPGEKV 226
+ E ++VGDI+++KPG+K+
Sbjct: 166 IPVEAIEVGDIMLIKPGQKL 185
>sp|P78036|ATCL_MYCPN PROBABLE CATION-TRANSPORTING P-TYPE ATPASE >gi|2146336|pir||S73948
Mg2+-transporting ATPase (EC 3.6.1.-) mgtA, P-type 1 -
Mycoplasma pneumoniae (strain ATCC 29342)
>gi|1674325|gb|AAB96270.1| (AE000059)
cation-transporting P-type ATPase [Mycoplasma
pneumoniae]
Length = 872
Score = 77.3 bits (187), Expect = 5e-13
Identities = 75/337 (22%), Positives = 153/337 (45%), Gaps = 33/337 (9%)
Query: 107 TLVFGLFLASYLISGWKVLKSAIVNSLNGN-VFDENFLIAVATIGAFLIKEYPEGVAVML 165
+LV L L + ++S L AI++ +N N +FD N +I E+ + +++
Sbjct: 42 SLVVILLLVATILS----LVVAIISGVNANWLFDHNLVI-----------EWTQPFVILI 86
Query: 166 FYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIVKPGEK 225
+ + + K+++S L +L + + R+ +V + E+ VGDII ++ G+
Sbjct: 87 TVLANSLIGSIQEFKAQKSAHTLKSLTQPFTRVFREEGLVSLPVGEVVVGDIIFLEAGDI 146
Query: 226 VPVDGVIIEGTS-SVDTSALTGESMPRTVKEGDEILSGMINLTGLL-----------KVR 273
+P DG +++ S LTGES+P + G++ T LL
Sbjct: 147 IPADGKVLQANHLRCMESFLTGESVPVDKSVVNTGGKGLLEQTNLLFSGAQVVFGSGVFE 206
Query: 274 VTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIATVP--PLVFK 331
VT + V +I++ V++++ + + ++ + + +++ +G+ ++ V L F
Sbjct: 207 VTAVGLNTQVGQIVKTVDSSATKLSPLQQKLEKVGKWFSWFGLGLFVVVFLVQLGLLGFH 266
Query: 332 ESFTSW---VYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKDAS 388
+W + A+ ++V P LV I + + + + K+ +IK ++ L
Sbjct: 267 NFSANWSIALIGAIALVVAIIPEGLVTFINVIFALSVQKLTKQKAIIKYLAAIETLGGVQ 326
Query: 389 IVAFDKTGTLTKGVFKVTKIETRNGFTEEEILRFAAL 425
I+ DKTGTLT+ KV + T+ ++ R L
Sbjct: 327 IICTDKTGTLTQNKMKVVDYFCFSNTTQTDLARALCL 363
Score = 70.2 bits (169), Expect = 7e-11
Identities = 49/195 (25%), Positives = 92/195 (47%), Gaps = 28/195 (14%)
Query: 494 TIAHVVIDGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSRDVAEEIAKQLGL 553
T+ + + + G + + D + ++ A+ + + + M+TGD A IAK+LG+
Sbjct: 478 TVNELESELDFLGSVSLQDPPRIESKAAIMACHQANITPI-MITGDHLKTATAIAKELGI 536
Query: 554 --------------------DGFYAELLPEDKVKIIEKLEKEKGNGKLVFVGDGINDAPV 593
+A + P+ K++I+ ++ + GDG+NDAP
Sbjct: 537 LTDERQAILGVDLDPAKIMEYRVFARVTPQQKLEIVNAWKQ--AGYTVAVTGDGVNDAPA 594
Query: 594 LARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIARKT----QRIVWENIIFAL 649
L +DVG MG G D A + ADV+I DD + + I+ RKT +R+++ + ++
Sbjct: 595 LVTSDVGCCMGQTGVDIAKDAADVIISDDNFATIVNGIEQGRKTFLTCKRVLFNLFLTSI 654
Query: 650 -GVKLAFIGLGIFGK 663
G + +GL + G+
Sbjct: 655 AGTIVVLLGLFVLGE 669
>gb|AAB52420.1| (U93845) Arabidopsis thaliana ER-type calcium pump protein,
complete sequence >gi|2078292|gb|AAC68819.1| (U96455)
ER-type Ca2+-pumping ATPase; ECA1p [Arabidopsis
thaliana] >gi|7106179|gb|AAF36087.1| (AF116533)
endoplasmic reticulum-type calcium-transporting ATPase 1
[Arabidopsis thaliana]
>gi|8439887|gb|AAF75073.1|AC007583_9 (AC007583) Strong
similarity to ER-type calcium pump protein from
Arabidopsis thaliana gb|U93845. ESTs gb|AA042787 and
gb|AI992578 come from this gene
Length = 1061
Score = 76.5 bits (185), Expect = 9e-13
Identities = 81/338 (23%), Positives = 146/338 (42%), Gaps = 40/338 (11%)
Query: 105 DNTLVFGLFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEYPEGVAVM 164
+ T +F L L + + ++L +A V S FD + G I + E + +
Sbjct: 67 EGTSIFKLILEQFNDTLVRILLAAAVISFVLAFFDGD------EGGEMGITAFVEPLVIF 120
Query: 165 LFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKP-EELKVGDIIIVKPG 223
L ++ + + ++++AL ++++ A ++RDGT V P +EL GDI+ ++ G
Sbjct: 121 LILIVNAIVGIWQETNAEKALEALKEIQSQQATVMRDGTKVSSLPAKELVPGDIVELRVG 180
Query: 224 EKVPVDG---VIIEGTSSVDTSALTGES--MPRTVKEGDE----------ILSGMINLTG 268
+KVP D +I T V+ +LTGES + +T K DE + +G + G
Sbjct: 181 DKVPADMRVVALISSTLRVEQGSLTGESEAVSKTTKHVDENADIQGKKCMVFAGTTVVNG 240
Query: 269 LLKVRVTRELSESTVSRILELVENASARKAKT--EKFITRFAHYYTPAVVGIATLIATVP 326
VT + + R+ ++ A+ + T +K + F T + I L+ +
Sbjct: 241 NCICLVTDTGMNTEIGRVHSQIQEAAQHEEDTPLKKKLNEFGEVLTMIIGLICALVWLIN 300
Query: 327 -------------PLVFKESFTSWVYR---ALVILVISCPCALVLSIPLGYFGGIGRAAK 370
P FK SF Y A+ + V + P L I G + A+
Sbjct: 301 VKYFLSWEYVDGWPRNFKFSFEKCTYYFEIAVALAVAAIPEGLPAVITTCLALGTRKMAQ 360
Query: 371 EGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKI 408
+ L++ ++ L +++ DKTGTLT V+K+
Sbjct: 361 KNALVRKLPSVETLGCTTVICSDKTGTLTTNQMAVSKL 398
>gb|AAF75088.1|AC007583_24 (AC007583) Strong similarity to ER-type calcium pump protein from
Arabidopsis thaliana gb|U93845. It is a member of
Na+/K+ ATPase C-terminus PF|00690 and a member of E1-E2
ATPase PF|00122
Length = 1061
Score = 76.5 bits (185), Expect = 9e-13
Identities = 81/338 (23%), Positives = 146/338 (42%), Gaps = 40/338 (11%)
Query: 105 DNTLVFGLFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEYPEGVAVM 164
+ T +F L L + + ++L +A V S FD + G I + E + +
Sbjct: 67 EGTSIFKLILEQFNDTLVRILLAAAVISFVLAFFDGD------EGGEMGITAFVEPLVIF 120
Query: 165 LFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKP-EELKVGDIIIVKPG 223
L ++ + + ++++AL ++++ A ++RDGT V P +EL GDI+ ++ G
Sbjct: 121 LILIVNAIVGIWQETNAEKALEALKEIQSQQATVMRDGTKVSSLPAKELVPGDIVELRVG 180
Query: 224 EKVPVDG---VIIEGTSSVDTSALTGES--MPRTVKEGDE----------ILSGMINLTG 268
+KVP D +I T V+ +LTGES + +T K DE + +G + G
Sbjct: 181 DKVPADMRVVALISSTLRVEQGSLTGESEAVSKTTKHVDENADIQGKKCMVFAGTTVVNG 240
Query: 269 LLKVRVTRELSESTVSRILELVENASARKAKT--EKFITRFAHYYTPAVVGIATLIATVP 326
VT + + R+ ++ A+ + T +K + F T + I L+ +
Sbjct: 241 NCICLVTDTGMNTEIGRVHSQIQEAAQHEEDTPLKKKLNEFGEVLTMIIGLICALVWLIN 300
Query: 327 -------------PLVFKESFTSWVYR---ALVILVISCPCALVLSIPLGYFGGIGRAAK 370
P FK SF Y A+ + V + P L I G + A+
Sbjct: 301 VKYFLSWEYVDGWPRNFKFSFEKCTYYFEIAVALAVAAIPEGLPAVITTCLALGTRKMAQ 360
Query: 371 EGILIKGSNYLDALKDASIVAFDKTGTLTKGVFKVTKI 408
+ L++ ++ L +++ DKTGTLT V+K+
Sbjct: 361 KNALVRKLPSVETLGCTTVICSDKTGTLTTNQMAVSKL 398
>emb|CAA17934.1| (AL022118) putative cation-transporting ATPase [Mycobacterium leprae]
Length = 1609
Score = 73.0 bits (176), Expect = 1e-11
Identities = 67/231 (29%), Positives = 101/231 (43%), Gaps = 37/231 (16%)
Query: 486 HDTCKVKGTIAHVVI----DGQYAGYIVISDEIKEDAHLAVKELKRLGVRKVVMVTGDSR 541
HDT T A V D + GYI ++D + + ++ L G R VV++TGD
Sbjct: 1208 HDTTDDNDTDADAVDAAAHDLELVGYIGLADTARPSSRPLIEALVTAG-RNVVLITGDHP 1266
Query: 542 DVAEEIAKQLGLDG--------------------------FYAELLPEDKVKIIEKLEKE 575
A IA+QLGL +A + PE KV+I+ L++
Sbjct: 1267 ITARAIAQQLGLRSDARVVNGTELIGLDEDACAELAADVQVFARVSPEQKVQIVAALQR- 1325
Query: 576 KGNGKLV-FVGDGINDAPVLARADVGVAMGALGSDAAIETADVVIMDDKPSKLPKAIQIA 634
G++ VGDG NDA + ADVG+ + GS AA AD+V+ DD L A+
Sbjct: 1326 --CGQVTAMVGDGANDAAAIRMADVGIGVSGRGSSAARGAADIVLTDDDLGVLLDALVEG 1383
Query: 635 RKTQRIVWENIIFALGVKLAFIGLGIFGKATMWEAVFADVGVALIAVFNAM 685
R V + + +G + + I G T++ A A VG + + N +
Sbjct: 1384 RSMWAGVRDAVTILVGGNVGEVVFTIIG--TVFGAGRAPVGTRQLLLVNLL 1432
>emb|CAA04499.2| (AJ001045) P-type cation-transporting ATPase [Blastocladiella
emersonii]
Length = 1080
Score = 73.0 bits (176), Expect = 1e-11
Identities = 79/328 (24%), Positives = 144/328 (43%), Gaps = 41/328 (12%)
Query: 97 LMRYY---YAIDNTLVFGLFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFL 153
L+RY A+ N L+ +YL+ G + + N++ + L+AVA + AF+
Sbjct: 69 LLRYLECLLALFNFLLLVAAAFTYLLYGLDPVSNY------ANIYTGSILVAVAFLNAFI 122
Query: 154 IKEYPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELK 213
E+ Q V KS +++A L + A VR G +V V +L
Sbjct: 123 -----------------EYYQ---VAKSEAALRAFLDMIPAKATAVRGGQLVVVPASDLV 162
Query: 214 VGDIIIVKPGEKVPVDGVIIE-GTSSVDTSALTGESMPR------TVKEGDEILSGMINL 266
GD++ V+ G+K+P D + + VD ++LTGES P+ T + E + N
Sbjct: 163 KGDVVFVRMGDKMPADVFLFKTADMKVDNASLTGESEPQDRSPVNTHEAALEATNLAFNS 222
Query: 267 TGLLKVR----VTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLI 322
T ++ V R ++ + +I + + + R + + I F + V A +
Sbjct: 223 TLVVAGEGYGIVVRTGDDTVIGQIANMTQTETKRMSPLTEEIEAFVKFIGSLAVLCAIIF 282
Query: 323 ATVPPLVFKESFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLD 382
+ L + S+ + A+ +LV P L ++ + R A + +L+K ++
Sbjct: 283 FIIAQLKTNDIGISFNF-AVGVLVAWVPEGLPGTVTMLLTIAAKRMAGQQVLVKDLTGVE 341
Query: 383 ALKDASIVAFDKTGTLTKGVFKVTKIET 410
L +++A DKTGTLT+ V+ + T
Sbjct: 342 TLGAITLLATDKTGTLTRNQMTVSNVWT 369
>pir||T43025 Na+/K+-exchanging ATPase (EC 3.6.1.37) alpha chain -
Blastocladiella emersonii
Length = 1080
Score = 73.0 bits (176), Expect = 1e-11
Identities = 79/328 (24%), Positives = 144/328 (43%), Gaps = 41/328 (12%)
Query: 97 LMRYY---YAIDNTLVFGLFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFL 153
L+RY A+ N L+ +YL+ G + + N++ + L+AVA + AF+
Sbjct: 69 LLRYLECLLALFNFLLLVAAAFTYLLYGLDPVSNY------ANIYTGSILVAVAFLNAFI 122
Query: 154 IKEYPEGVAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELK 213
E+ Q V KS +++A L + A VR G +V V +L
Sbjct: 123 -----------------EYYQ---VAKSEAALRAFLDMIPAKATAVRGGQLVVVPASDLV 162
Query: 214 VGDIIIVKPGEKVPVDGVIIE-GTSSVDTSALTGESMPR------TVKEGDEILSGMINL 266
GD++ V+ G+K+P D + + VD ++LTGES P+ T + E + N
Sbjct: 163 KGDVVFVRMGDKMPADVFLFKTADMKVDNASLTGESEPQDRSPVNTHEAALEATNLAFNS 222
Query: 267 TGLLKVR----VTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLI 322
T ++ V R ++ + +I + + + R + + I F + V A +
Sbjct: 223 TLVVAGEGYGIVVRTGDDTVIGQIANMTQTETKRMSPLTEEIEAFVKFIGSLAVLCAIIF 282
Query: 323 ATVPPLVFKESFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLD 382
+ L + S+ + A+ +LV P L ++ + R A + +L+K ++
Sbjct: 283 FIIAQLKTNDIGISFNF-AVGVLVAWVPEGLPGTVTMLLTIAAKRMAGQQVLVKDLTGVE 341
Query: 383 ALKDASIVAFDKTGTLTKGVFKVTKIET 410
L +++A DKTGTLT+ V+ + T
Sbjct: 342 TLGAITLLATDKTGTLTRNQMTVSNVWT 369
>sp|P50996|ATHA_CANFA POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN (PROTON PUMP) (GASTRIC
H+/K+ ATPASE ALPHA SUBUNIT) >gi|163959|gb|AAA30848.1|
(L11568) H+,K+-ATPase [Canis familiaris]
Length = 1034
Score = 71.8 bits (173), Expect = 2e-11
Identities = 74/322 (22%), Positives = 131/322 (39%), Gaps = 33/322 (10%)
Query: 101 YYAIDNTLVFGLFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEYPEG 160
Y L GL ++ + ++ AI S D+N +A+A I ++
Sbjct: 99 YVKFARQLAGGLQCLMWVAAAICLIAFAIQASEGDLTTDDNLYLALALIAVVVVTG---- 154
Query: 161 VAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIV 220
F EF KS I + L + A ++RDG ++ ++L VGD++ +
Sbjct: 155 ----CFGYYQEF-------KSTNIIASFKNLVPQQATVIRDGDKFQINADQLVVGDLVEM 203
Query: 221 KPGEKVPVDGVIIEGTS-SVDTSALTGESMPRT----------VKEGDEILSGMINLTGL 269
K G++VP D I++ VD S+LTGES P+T ++ + L + L G
Sbjct: 204 KGGDRVPADIRILQAQGCKVDNSSLTGESEPQTRSPECTHESPLETRNIALFSTMCLEGT 263
Query: 270 LKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIAT---VP 326
+ V + + RI L K I ++ + G+A L V
Sbjct: 264 AQGLVVNTGDRTIIGRIASLASGVENEKTP----IAIEIEHFVDIIAGLAILFGATFFVV 319
Query: 327 PLVFKESFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKD 386
+ +F + + I+V P L+ ++ + R A + ++K ++ L
Sbjct: 320 AMCIGYTFLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGS 379
Query: 387 ASIVAFDKTGTLTKGVFKVTKI 408
S++ DKTGTLT+ V+ +
Sbjct: 380 KSVICSDKTGTLTQNSMTVSNL 401
>pir||JN0903 H+/K+-exchanging ATPase (EC 3.6.1.36) alpha chain - dog
Length = 1034
Score = 69.9 bits (168), Expect = 9e-11
Identities = 73/322 (22%), Positives = 130/322 (39%), Gaps = 33/322 (10%)
Query: 101 YYAIDNTLVFGLFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEYPEG 160
Y L GL ++ + ++ AI S D+N +A+A I ++
Sbjct: 99 YVKFARQLAGGLQCLMWVAAAICLIAFAIQASEGDLTTDDNLYLALALIAVVVVTG---- 154
Query: 161 VAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIV 220
F EF KS I + L + A ++RDG ++ ++L VGD++ +
Sbjct: 155 ----CFGYYQEF-------KSTNIIASFKNLVPQQATVIRDGDKFQINADQLVVGDLVEM 203
Query: 221 KPGEKVPVDGVIIEGTS-SVDTSALTGESMPRT----------VKEGDEILSGMINLTGL 269
K G++VP D I++ VD S+LTGES P+T ++ + + L G
Sbjct: 204 KGGDRVPADIRILQAQGCKVDNSSLTGESEPQTRSPECTHESPLETRNIAFFSTMCLEGT 263
Query: 270 LKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIAT---VP 326
+ V + + RI L K I ++ + G+A L V
Sbjct: 264 AQGLVVNTGDRTIIGRIASLASGVENEKTP----IAIEIEHFVDIIAGLAILFGATFFVV 319
Query: 327 PLVFKESFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKD 386
+ +F + + I+V P L+ ++ + R A + ++K ++ L
Sbjct: 320 AMCIGYTFLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGS 379
Query: 387 ASIVAFDKTGTLTKGVFKVTKI 408
S++ DKTGTLT+ V+ +
Sbjct: 380 TSVICSDKTGTLTQNRMTVSHL 401
>gi|9055170 ATPase, H+/K+ transporting, alpha polypeptide [Mus musculus]
>gi|2118224|pir||I49143 gastric H(+)-K(+)-ATPase alpha
subunit - mouse >gi|596068|gb|AAA79514.1| (U17282)
gastric H(+)-K(+)-ATPase alpha subunit [Mus musculus]
>gi|1096609|prf||2112198B Na channel:SUBUNIT=gamma [Homo
sapiens]
Length = 1033
Score = 69.9 bits (168), Expect = 9e-11
Identities = 74/322 (22%), Positives = 129/322 (39%), Gaps = 33/322 (10%)
Query: 101 YYAIDNTLVFGLFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEYPEG 160
Y L GL ++ + ++ AI S D+N +AVA I ++
Sbjct: 98 YVKFARQLAGGLQCLMWVAAAICLIAFAIQASEGDLTTDDNLYLAVALIAVVVVTG---- 153
Query: 161 VAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIV 220
F EF KS I + L + A ++RDG ++ ++L VGD++ +
Sbjct: 154 ----CFGYYQEF-------KSTNIIASFKNLVPQQATVIRDGDKFQINADQLVVGDLVEM 202
Query: 221 KPGEKVPVDGVIIEGTS-SVDTSALTGESMPRT----------VKEGDEILSGMINLTGL 269
K G++VP D I+ VD S+LTGES P+T ++ + + L G
Sbjct: 203 KGGDRVPADIRILSAQGCKVDNSSLTGESEPQTRSPECTHESPLETRNIAFFSTMCLEGT 262
Query: 270 LKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIAT---VP 326
+ V + + RI L K I ++ + G+A L V
Sbjct: 263 AQGLVVSTGDRTIIGRIASLASGVENEKTP----IAIEIEHFVDIIAGLAILFGATFFVV 318
Query: 327 PLVFKESFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKD 386
+ +F + + I+V P L+ ++ + R A + ++K ++ L
Sbjct: 319 AMCIGYTFLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGS 378
Query: 387 ASIVAFDKTGTLTKGVFKVTKI 408
S++ DKTGTLT+ V+ +
Sbjct: 379 TSVICSDKTGTLTQNRMTVSHL 400
>gi|11426740 ATPase, H+/K+ exchanging, alpha polypeptide [Homo sapiens]
>gi|1905895|gb|AAB50172.1| (AD000090) human gastric
H,K-ATPase catalytic subunit [Homo sapiens]
Length = 1035
Score = 69.9 bits (168), Expect = 9e-11
Identities = 72/322 (22%), Positives = 130/322 (40%), Gaps = 33/322 (10%)
Query: 101 YYAIDNTLVFGLFLASYLISGWKVLKSAIVNSLNGNVFDENFLIAVATIGAFLIKEYPEG 160
Y L GL ++ + ++ AI S D+N +A+A I ++
Sbjct: 100 YVKFARQLAGGLQCLMWVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTG---- 155
Query: 161 VAVMLFYVIGEFLQDMAVDKSRRSIKALLALKAEYANLVRDGTVVKVKPEELKVGDIIIV 220
F EF KS I + L + A ++RDG ++ ++L VGD++ +
Sbjct: 156 ----CFGYYQEF-------KSTNIIASFKNLVPQQATVIRDGDKFQINADQLVVGDLVEM 204
Query: 221 KPGEKVPVDGVIIEGTS-SVDTSALTGESMPRT----------VKEGDEILSGMINLTGL 269
K G++VP D I+ VD S+LTGES P+T ++ + + L G
Sbjct: 205 KGGDRVPADIRILAAQGCKVDNSSLTGESEPQTRSPECTHESPLETRNIAFFSTMCLEGT 264
Query: 270 LKVRVTRELSESTVSRILELVENASARKAKTEKFITRFAHYYTPAVVGIATLIAT---VP 326
++ V + + RI L K I ++ + G+A L +
Sbjct: 265 VQGLVVNTGDRTIIGRIASLASGVENEKTP----IAIEIEHFVDIIAGLAILFGATFFIV 320
Query: 327 PLVFKESFTSWVYRALVILVISCPCALVLSIPLGYFGGIGRAAKEGILIKGSNYLDALKD 386
+ +F + + I+V P L+ ++ + R A + ++K ++ L
Sbjct: 321 AMCIGYTFLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGS 380
Query: 387 ASIVAFDKTGTLTKGVFKVTKI 408
S++ DKTGTLT+ V+ +
Sbjct: 381 TSVICSDKTGTLTQNRMTVSHL 402
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.320 0.139 0.386
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 232555644
Number of Sequences: 2977
Number of extensions: 9549700
Number of successful extensions: 34641
Number of sequences better than 1.0e-10: 381
Number of HSP's better than 0.0 without gapping: 154
Number of HSP's successfully gapped in prelim test: 227
Number of HSP's that attempted gapping in prelim test: 32697
Number of HSP's gapped (non-prelim): 894
length of query: 689
length of database: 189,106,746
effective HSP length: 60
effective length of query: 629
effective length of database: 153,197,526
effective search space: 96361243854
effective search space used: 96361243854
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 168 (69.9 bits)