BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB0646 (aspS) DE:aspartyl-tRNA synthetase (aspS)
         (438 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||A75071 aspartyl-tRNA synthetase (asps) PAB0646 - Pyrococcus...   889  0.0
sp|O58776|SYD_PYRHO ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI...   844  0.0
sp|Q52428|SYD_PYRKO ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI...   773  0.0
pdb|1B8A|A Chain A, Aspartyl-Trna Synthetase >gi|4388837|pdb|1B8...   770  0.0
gi|11498525 aspartyl-tRNA synthetase (aspS) [Archaeoglobus fulgi...   527  e-149
sp|Q58950|SYD_METJA ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI...   514  e-145
sp|O26328|SYD_METTH ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI...   495  e-139
sp|O24822|SYD_HALVO ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI...   412  e-114
sp|Q9Y9U7|SYD_AERPE ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI...   404  e-112
pir||C72527 probable aspartyl-tRNA synthetase APE2192 - Aeropyru...   397  e-109
emb|CAC12075.1| (AL445066) aspartyl-tRNA synthetase related prot...   390  e-107
gb|AAK40519.1| Aspartyl-tRNA synthetase (aspS) [Sulfolobus solfa...   383  e-105
sp|O07683|SYD_HALSA ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI...   370  e-101
gb|AAF61689.1| (AF219996) aspartyl-tRNA synthetase 2 [Thermus th...   326  2e-88
pir||H75443 aspartyl-tRNA synthetase, non-discriminating - Deino...   318  9e-86
pir||D75212 asparagine--tRNA ligase (EC 6.1.1.22) PAB2203 - Pyro...   305  8e-82
pir||B71248 asparagine--tRNA ligase (EC 6.1.1.22) - Pyrococcus h...   301  9e-81
pir||T04810 aspartate--tRNA ligase homolog F10M23.210 - Arabidop...   292  5e-78
emb|CAC11659.1| (AL445064) probable asparaginyl--tRNA synthetase...   281  1e-74
gi|4557513 aspartyl-tRNA synthetase [Homo sapiens] >gi|135098|sp...   276  3e-73
gi|6323011 Aspartyl-tRNA synthetase, cytosolic; Dps1p [Saccharom...   275  7e-73
pdb|1ASZ|A Chain A, Aspartyl Trna Synthetase (Asprs) (E.C.6.1.1....   275  7e-73
pdb|1EOV|A Chain A, Free Aspartyl-Trna Synthetase (Asprs) (E.C. ...   275  7e-73
gi|11429379 aspartyl-tRNA synthetase [Homo sapiens]                   275  7e-73
sp|P15178|SYD_RAT ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGA...   275  9e-73
sp|P39772|SYN_BACSU ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRN...   275  9e-73
pir||T40867 aspartate--tRNA ligase (EC 6.1.1.12) [similarity] - ...   273  2e-72
pir||T10672 aspartate--tRNA ligase homolog F6E21.100 - Arabidops...   273  3e-72
gb|AAF58445.1| (AE003820) Aats-asp gene product [Drosophila mela...   265  6e-70
gb|AAD21582.1| (AF113612) aspartyl tRNA synthetase [Drosophila m...   263  3e-69
sp|Q03577|SYD_CAEEL PROBABLE ASPARTYL-TRNA SYNTHETASE (ASPARTATE...   259  6e-68
pir||S71074 asparagine--tRNA ligase (EC 6.1.1.22) asnS2 - Lactob...   254  2e-66
pir||S71072 asparagine--tRNA ligase (EC 6.1.1.22) asnS1 - Lactob...   252  4e-66
sp|P54262|SYN_LACDE ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRN...   252  4e-66
dbj|BAB05415.1| (AP001512) asparaginyl-tRNA synthetase [Bacillus...   250  3e-65
sp|P54263|SYN_THETH ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRN...   228  1e-58
sp|Q19722|SYN_CAEEL PROBABLE ASPARAGINYL-TRNA SYNTHETASE, CYTOPL...   196  4e-49
gb|AAD55420.1|AF181634_1 (AF181634) BcDNA.GH06451 [Drosophila me...   192  8e-48
gi|4758762 asparaginyl-tRNA synthetase [Homo sapiens] >gi|391505...   191  1e-47
gi|11426051 asparaginyl-tRNA synthetase [Homo sapiens]                191  1e-47
sp|P75521|SYN_MYCPN ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRN...   190  2e-47
gi|6321807 Asparaginyl-tRNA synthetase; Ded81p [Saccharomyces ce...   189  6e-47
sp|P47359|SYN_MYCGE ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRN...   189  7e-47
sp|P43829|SYN_HAEIN ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRN...   183  4e-45
pir||A82901 asparaginyl-tRNA synthetase UU365 [imported] - Ureap...   181  1e-44
sp|P10723|SYN_BRUMA ASPARAGINYL-TRNA SYNTHETASE, CYTOPLASMIC (AS...   181  2e-44
sp|P17242|SYN_ECOLI ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRN...   180  3e-44
pir||T39675 asparaginyl-trna synthetase - fission yeast  (Schizo...   180  3e-44
emb|CAB91185.1| (AL355921) asparaginyl-trna synthetase, mitochon...   180  4e-44
pir||A28209 60K filarial antigen - nematode (Brugia malayi) >gi|...   179  5e-44
sp|P52276|SYN_SYNY3 PROBABLE ASPARAGINYL-TRNA SYNTHETASE (ASPARA...   178  1e-43
pir||E82217 asparaginyl-tRNA synthetase VC1297 [imported] - Vibr...   178  1e-43
sp|O67589|SYD_AQUAE ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI...   171  1e-41
emb|CAA10904.1| (AJ222644) asparaginyl-tRNA synthetase [Arabidop...   171  2e-41
sp|O51128|SYN_BORBU ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRN...   168  2e-40
pir||F82540 asparaginyl-tRNA synthetase XF2563 [imported] - Xyle...   166  6e-40
sp|O32038|SYD_BACSU ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI...   160  3e-38
sp|P56459|SYD_HELPY ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI...   159  8e-38
sp|P57441|SYN_BUCAI ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRN...   157  2e-37
sp|Q9X1F4|SYD_THEMA ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI...   157  2e-37
sp|Q9ZLL9|SYD_HELPJ ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI...   155  7e-37
sp|P36419|SYD_THETH ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI...   153  3e-36
sp|O83618|SYN_TREPA ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRN...   151  1e-35
pir||H82627 aspartyl-tRNA synthetase XF1856 [imported] - Xylella...   150  2e-35
pir||H71612 asparagine--tRNA ligase (EC 6.1.1.22) (OO, TP) PFB05...   150  2e-35
gb|AAD46681.1|AF170909_1 (AF170909) SYNC1 protein [Arabidopsis t...   148  1e-34
pir||E83524 aspartyl-tRNA synthetase PA0963 [imported] - Pseudom...   148  2e-34
dbj|BAB04971.1| (AP001511) aspartyl-tRNA synthetase [Bacillus ha...   146  3e-34
sp|P41255|SYK_THETH LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ...   146  4e-34
pir||D82910 aspartyl-tRNA synthetase UU286 [imported] - Ureaplas...   143  3e-33
gi|6319872 Asn-tRNA synthetase; Ycr024cp [Saccharomyces cerevisi...   142  9e-33
gb|AAD55509.1|AC008148_19 (AC008148) Similar to  asparaginyl-tRN...   141  1e-32
sp|P73443|SYK_SYNY3 LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ...   140  3e-32
sp|P56126|SYK_HELPY LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ...   140  3e-32
pir||D75406 aspartyl-tRNA synthetase, discriminating - Deinococc...   140  3e-32
pir||D83183 lysyl-tRNA synthetase PA3700 [imported] - Pseudomona...   140  3e-32
sp|O87821|SYK_RHIME LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ...   139  4e-32
sp|P73851|SYD_SYNY3 ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI...   139  4e-32
gb|AAF57921.1| (AE003804) CG6796 gene product [Drosophila melano...   139  6e-32
sp|P75068|SYD_MYCPN ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI...   138  1e-31
pir||A42609 lysine--tRNA ligase (EC 6.1.1.6) - Campylobacter jej...   137  3e-31
sp|P41258|SYK_CAMJE LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ...   137  3e-31
sp|P57512|SYK_BUCAI LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ...   137  3e-31
dbj|BAB15655.1| (AK027094) unnamed protein product [Homo sapiens]     137  3e-31
pir||F82234 aspartyl-tRNA synthetase VC1166 [imported] - Vibrio ...   136  4e-31
sp|P14825|SYK2_ECOLI LYSYL-TRNA SYNTHETASE, HEAT INDUCIBLE (LYSI...   136  6e-31
pdb|1E1O|A Chain A, Lysyl-Trna Synthetase (Lysu) Hexagonal For, ...   136  6e-31
sp|O67258|SYK_AQUAE LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ...   134  2e-30
sp|P47282|SYD_MYCGE ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI...   134  3e-30
sp|Q9ZMP8|SYK_HELPJ LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ...   134  3e-30
pir||G81412 aspartate--tRNA ligase (EC 6.1.1.12) Cj0640c [import...   134  3e-30
gb|AAK40448.1| Lysyl-tRNA synthetase (lysS) [Sulfolobus solfatar...   132  6e-30
sp|P95970|SYK_SULSO LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ...   132  6e-30
sp|P43825|SYK_HAEIN LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ...   132  7e-30
pir||G81195 aspartyl-tRNA synthetase NMB0466 [imported] - Neisse...   132  1e-29
sp|P13030|SYK1_ECOLI LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE)...   131  1e-29
sp|Q9KGG4|SYK_BACHD LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ...   131  1e-29
pdb|1BBU|A Chain A, Lysyl-Trna Synthetase (Lyss) Complexed With ...   131  1e-29
emb|CAC11748.1| (AL445064) asparagine--tRNA ligase related prote...   131  2e-29
sp|Q9RHV9|SYK_BACST LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ...   131  2e-29
pir||F81831 aspartate--tRNA ligase (EC 6.1.1.12) NMA2019 [import...   131  2e-29
pir||JC7205 lysine-tRNA ligase (AMP forming) (EC 6.1.1.6) - Baci...   131  2e-29
emb|CAC08476.1| (AL392189) aspartyl-tRNA synthetase [Streptomyce...   130  3e-29
sp|P37477|SYK_BACSU LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ...   130  4e-29
sp|Q53638|SYK_STAAU LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ...   130  4e-29
pir||S77851 probable aspartate--tRNA ligase (EC 6.1.1.12) - Myco...   129  6e-29
sp|Q9X231|SYK_THEMA LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ...   128  1e-28
pir||E81660 aspartyl-tRNA synthetase TC0829 [imported] - Chlamyd...   128  1e-28
sp|Q43990|SYK_ACICA LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ...   127  2e-28
sp|P43817|SYD_HAEIN ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI...   127  2e-28
sp|Q9ZE17|SYD_RICPR ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI...   126  6e-28
gb|AAF46510.1| (AE003447) CG12141 gene product [Drosophila melan...   126  6e-28
pir||B81858 lysine--tRNA ligase (EC 6.1.1.6) NMA1638 [imported] ...   126  6e-28
sp|Q49158|SYK_MYCFE LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ...   125  1e-27
sp|O84546|SYD_CHLTR ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI...   125  1e-27
pir||C81086 lysyl-tRNA synthetase, heat inducible NMB1425 [impor...   125  1e-27
sp|P21889|SYD_ECOLI ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI...   122  6e-27
sp|O83950|SYD_TREPA ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI...   122  6e-27
pdb|1C0A|A Chain A, Crystal Structure Of The E. Coli Aspartyl-Tr...   122  6e-27
sp|P57401|SYD_BUCAI ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI...   122  6e-27
sp|Q50649|SYD_MYCTU ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI...   121  1e-26
sp|Q9Z7P2|SYD_CHLPN ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI...   120  3e-26
sp|O51402|SYD_BORBU ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI...   120  4e-26
sp|Q9PEB6|SYK_XYLFA LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ...   119  7e-26
gb|AAA24096.1| (M30630) lysyl-tRNA synthetase (lysU) (E.C. 6.1.1...   118  1e-25
sp|P36429|SYD_MYCLE ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI...   118  2e-25
pir||S69892 lysine--tRNA ligase (EC 6.1.1.6) - Mycoplasma hominis     116  4e-25
sp|P37879|SYK_CRILO LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ...   116  4e-25
dbj|BAA06688.1| (D31890) similar to lysyl tRNA synthetase. [Homo...   116  6e-25
gi|5031815 lysyl-tRNA synthetase; lysine tRNA ligase [Homo sapie...   116  6e-25
sp|Q15046|SYK_HUMAN LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ...   116  6e-25
gb|AAG30114.1|AF285758_1 (AF285758) lysyl-tRNA synthetase [Homo ...   116  6e-25
sp|P81432|SYD_BUCAP ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI...   115  8e-25
sp|Q22099|SYK_CAEEL PROBABLE LYSYL-TRNA SYNTHETASE (LYSINE--TRNA...   114  2e-24
emb|CAA39699.1| (X56259) lysine--tRNA ligase [Saccharomyces cere...   114  2e-24
gi|6320242 lysyl-tRNA synthetase; Krs1p [Saccharomyces cerevisia...   113  3e-24
sp|Q9PR83|SYK_UREPA LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ...   113  4e-24
sp|P46191|SYK_MYCHO LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ...   112  7e-24
dbj|BAA35676.1| (D90730) Asparaginyl-tRNA synthetase (EC  6.1.1....   112  7e-24
emb|CAA10905.1| (AJ222645) asparaginyl-tRNA synthetase [Arabidop...   111  1e-23
gb|AAD46682.1|AF170910_1 (AF170910) SYNC2 protein [Arabidopsis t...   111  1e-23
gb|AAF02166.1|AC009853_26 (AC009853) putative asparaginyl-tRNA s...   111  1e-23
pir||T04993 probable aspartate--tRNA ligase (EC 6.1.1.12) T16L1....   110  3e-23
emb|CAB89697.1| (AJ276418) putative lysyl tRNA synthetase [Xanth...   110  4e-23
sp|Q9KU60|SYK_VIBCH LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ...   109  5e-23
gb|AAF53577.2| (AE003652) CG17938 gene product [Drosophila melan...   107  3e-22
sp|P47382|SYK_MYCGE LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ...   106  7e-22
pir||S70779 asparagine--tRNA ligase (EC 6.1.1.22) - Xenorhabdus ...    99  9e-20
dbj|BAA99139.1| (AP002548) lysyl tRNA synthetase [Chlamydophila ...    98  2e-19
sp|Q9Z6X5|SYK_CHLPN LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ...    98  3e-19
pir||T41563 hypothetical protein SPCC736.06 - fission yeast  (Sc...    96  8e-19
pir||E70155 aspartate--tRNA ligase (EC 6.1.1.12) aspS - Lyme dis...    91  2e-17
pir||S77842 probable asparagine--tRNA ligase (EC 6.1.1.22) - Myc...    89  8e-17
gi|6325153 Aspartyl-tRNA synthetase, mitochondrial; Msd1p [Sacch...    89  1e-16
dbj|BAA90843.1| (AB031211) LysS [Bacillus halodurans]                  85  2e-15
sp|Q56112|SYN_SALTI ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRN...    83  6e-15
pir||C75215 asparaginyl-tRNA synthetase related protein PAB2356 ...    75  1e-12
pir||E82050 lysyl-tRNA synthetase-related protein VC2655 [import...    71  2e-11
sp|Q9Z614|SYK3_BUCAP PUTATIVE LYSYL-TRNA SYNTHETASE (LYSINE--TRN...    70  4e-11
gb|AAD12351.1| (U01814) unknown [Mycoplasma genitalium]                69  7e-11

>pir||A75071 aspartyl-tRNA synthetase (asps) PAB0646 - Pyrococcus abyssi
           (strain Orsay) >gi|5458382|emb|CAB49870.1| (AJ248286)
           aspartyl-tRNA synthetase (aspS) [Pyrococcus abyssi]
           Length = 438
           
 Score =  889 bits (2271), Expect = 0.0
 Identities = 438/438 (100%), Positives = 438/438 (100%)

Query: 1   MLRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF 60
           MLRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF
Sbjct: 1   MLRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF 60

Query: 61  KLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTR 120
           KLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTR
Sbjct: 61  KLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTR 120

Query: 121 LDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKY 180
           LDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKY
Sbjct: 121 LDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKY 180

Query: 181 FENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESE 240
           FENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESE
Sbjct: 181 FENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESE 240

Query: 241 EEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIP 300
           EEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIP
Sbjct: 241 EEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIP 300

Query: 301 WGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGV 360
           WGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGV
Sbjct: 301 WGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGV 360

Query: 361 EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDI 420
           EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDI
Sbjct: 361 EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDI 420

Query: 421 GNIREVILFPRDRRRLVP 438
           GNIREVILFPRDRRRLVP
Sbjct: 421 GNIREVILFPRDRRRLVP 438


>sp|O58776|SYD_PYRHO ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
           >gi|7437590|pir||G71094 aspartate--tRNA ligase (EC
           6.1.1.12) - Pyrococcus horikoshii
           >gi|3257434|dbj|BAA30117.1| (AP000004) 438aa long
           hypothetical aspartyl-tRNA synthetase [Pyrococcus
           horikoshii]
           Length = 438
           
 Score =  844 bits (2157), Expect = 0.0
 Identities = 409/438 (93%), Positives = 429/438 (97%)

Query: 1   MLRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF 60
           MLRTHYS+EITEELNGK+VKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKV QEIF
Sbjct: 1   MLRTHYSNEITEELNGKRVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVSQEIF 60

Query: 61  KLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTR 120
           KLIPKLNSEDVIVVEGIVNFTPKAKLGFE+IPEKLEVIS+AKTPLPLDPTGKVKAELDTR
Sbjct: 61  KLIPKLNSEDVIVVEGIVNFTPKAKLGFEVIPEKLEVISRAKTPLPLDPTGKVKAELDTR 120

Query: 121 LDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKY 180
           LDNRFMDLRNP+VM+IFKIRSSVFRA REFFY EGFIEIHTPKIIATATEGGTELFPLKY
Sbjct: 121 LDNRFMDLRNPKVMAIFKIRSSVFRAVREFFYSEGFIEIHTPKIIATATEGGTELFPLKY 180

Query: 181 FENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESE 240
           FE DAFLAQSPQLYKQMMM+TGLDKVFEI PIFRAEEHNTTRHLNEAWSIDAEMAFIE+E
Sbjct: 181 FERDAFLAQSPQLYKQMMMATGLDKVFEIAPIFRAEEHNTTRHLNEAWSIDAEMAFIENE 240

Query: 241 EEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIP 300
            EVMDLLERLI YVINYVRE+NEKELK LEFELNEPK+PFPRITYD+ALEILSDLGKEIP
Sbjct: 241 GEVMDLLERLISYVINYVREHNEKELKTLEFELNEPKRPFPRITYDKALEILSDLGKEIP 300

Query: 301 WGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGV 360
           WGEDIDTEGEKLLGKYM ENEGA+LYFIYRYPSEAKPFYIMKY++KPEVC+AFDLEYRGV
Sbjct: 301 WGEDIDTEGEKLLGKYMAENEGADLYFIYRYPSEAKPFYIMKYDEKPEVCRAFDLEYRGV 360

Query: 361 EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDI 420
           EISSGGQREHRHD+L+EQI+EKGLNP+SFEFYL+AFEYGMPPHGGFGLGAERLIMRMLDI
Sbjct: 361 EISSGGQREHRHDVLLEQIKEKGLNPKSFEFYLKAFEYGMPPHGGFGLGAERLIMRMLDI 420

Query: 421 GNIREVILFPRDRRRLVP 438
           GNIREVILFPRDRRRLVP
Sbjct: 421 GNIREVILFPRDRRRLVP 438


>sp|Q52428|SYD_PYRKO ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
           >gi|2129413|pir||JC4352 aspartate--tRNA ligase (EC
           6.1.1.12) - Pyrococcus sp >gi|1136773|dbj|BAA08115.1|
           (D45167) aspartyl-tRNA synthetase [Pyrococcus sp.]
           Length = 438
           
 Score =  773 bits (1975), Expect = 0.0
 Identities = 364/438 (83%), Positives = 408/438 (93%)

Query: 1   MLRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF 60
           M RTHYSSEITEELNG+KVKVAGWV EVKDLGGIKF+WIRDR+GIVQ+TAPKKKV  E+F
Sbjct: 1   MYRTHYSSEITEELNGQKVKVAGWVWEVKDLGGIKFLWIRDRDGIVQITAPKKKVDPELF 60

Query: 61  KLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTR 120
           KLIPKL SEDV+ VEG+VNFTPKAKLGFEI+PEK+ V+++A+TPLPLDPTGKVKAELDTR
Sbjct: 61  KLIPKLRSEDVVAVEGVVNFTPKAKLGFEILPEKIVVLNRAETPLPLDPTGKVKAELDTR 120

Query: 121 LDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKY 180
           LDNRFMDLR P VM+IFKIRSSVF+A R+FF++ GFIEIHTPKIIATATEGGTELFP+KY
Sbjct: 121 LDNRFMDLRRPEVMAIFKIRSSVFKAVRDFFHENGFIEIHTPKIIATATEGGTELFPMKY 180

Query: 181 FENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESE 240
           FE DAFLAQSPQLYKQ+MM++GLD+V+EI PIFRAEEHNTTRHLNEAWSID+EMAFIE E
Sbjct: 181 FEEDAFLAQSPQLYKQIMMASGLDRVYEIAPIFRAEEHNTTRHLNEAWSIDSEMAFIEDE 240

Query: 241 EEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIP 300
           EEVM  LERL+ + INYVRE+N KEL IL FEL EPK PFPR++YD+ALEIL DLGKEIP
Sbjct: 241 EEVMSFLERLVAHAINYVREHNAKELDILNFELEEPKLPFPRVSYDKALEILGDLGKEIP 300

Query: 301 WGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGV 360
           WGEDIDTEGE+LLGKYM+ENE A LYF+Y+YPSEAKPFYIMKY++KPE+C+AFDLEYRGV
Sbjct: 301 WGEDIDTEGERLLGKYMMENENAPLYFLYQYPSEAKPFYIMKYDNKPEICRAFDLEYRGV 360

Query: 361 EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDI 420
           EISSGGQREHRHDILVEQI+EKGLNPESFEFYL+AF YGMPPHGGFGLGAER+I +MLD+
Sbjct: 361 EISSGGQREHRHDILVEQIKEKGLNPESFEFYLKAFRYGMPPHGGFGLGAERVIKQMLDL 420

Query: 421 GNIREVILFPRDRRRLVP 438
            NIREVILFPRDRRRL P
Sbjct: 421 PNIREVILFPRDRRRLTP 438


>pdb|1B8A|A Chain A, Aspartyl-Trna Synthetase >gi|4388837|pdb|1B8A|B Chain B,
           Aspartyl-Trna Synthetase
           Length = 438
           
 Score =  770 bits (1967), Expect = 0.0
 Identities = 362/438 (82%), Positives = 408/438 (92%)

Query: 1   MLRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF 60
           M RTHYSSEITEELNG+KVKVAGWV EVKDLGGIKF+WIRDR+GIVQ+TAPKKKV  E+F
Sbjct: 1   MYRTHYSSEITEELNGQKVKVAGWVWEVKDLGGIKFLWIRDRDGIVQITAPKKKVDPELF 60

Query: 61  KLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTR 120
           KLIPKL SEDV+ VEG+VNFTPKAKLGFEI+PEK+ V+++A+TPLPLDPTGKVKAELDTR
Sbjct: 61  KLIPKLRSEDVVAVEGVVNFTPKAKLGFEILPEKIVVLNRAETPLPLDPTGKVKAELDTR 120

Query: 121 LDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKY 180
           L+NRFMDLR P VM+IFKIRSSVF+A R+FF++ GFIEIHTPKIIATATEGGTELFP+KY
Sbjct: 121 LNNRFMDLRRPEVMAIFKIRSSVFKAVRDFFHENGFIEIHTPKIIATATEGGTELFPMKY 180

Query: 181 FENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESE 240
           FE DAFLA+SPQLYK++MM++GLD+V+EI PIFRAEEHNTTRHLNEAWSID+EMAFIE E
Sbjct: 181 FEEDAFLAESPQLYKEIMMASGLDRVYEIAPIFRAEEHNTTRHLNEAWSIDSEMAFIEDE 240

Query: 241 EEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIP 300
           EEVM  LERL+ + INYVRE+N KEL IL FEL EPK PFPR++YD+ALEIL DLGKEIP
Sbjct: 241 EEVMSFLERLVAHAINYVREHNAKELDILNFELEEPKLPFPRVSYDKALEILGDLGKEIP 300

Query: 301 WGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGV 360
           WGEDIDTEGE+LLGKYM+ENE A LYF+Y+YPSEAKPFYIMKY++KPE+C+AFDLEYRGV
Sbjct: 301 WGEDIDTEGERLLGKYMMENENAPLYFLYQYPSEAKPFYIMKYDNKPEICRAFDLEYRGV 360

Query: 361 EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDI 420
           EISSGGQREHRHDILVEQI+EKGLNPESFEFYL+AF YGMPPHGGFGLGAERLI +MLD+
Sbjct: 361 EISSGGQREHRHDILVEQIKEKGLNPESFEFYLKAFRYGMPPHGGFGLGAERLIKQMLDL 420

Query: 421 GNIREVILFPRDRRRLVP 438
            NIREVILFPRDRRRL P
Sbjct: 421 PNIREVILFPRDRRRLTP 438


>gi|11498525 aspartyl-tRNA synthetase (aspS) [Archaeoglobus fulgidus]
           >gi|3122883|sp|O29342|SYD_ARCFU ASPARTYL-TRNA SYNTHETASE
           (ASPARTATE--TRNA LIGASE) (ASPRS) >gi|7437591|pir||H69364
           aspartyl-tRNA synthetase (aspS) homolog - Archaeoglobus
           fulgidus >gi|2649677|gb|AAB90318.1| (AE001040)
           aspartyl-tRNA synthetase (aspS) [Archaeoglobus fulgidus]
           Length = 430
           
 Score =  527 bits (1344), Expect = e-149
 Identities = 262/433 (60%), Positives = 326/433 (74%), Gaps = 6/433 (1%)

Query: 6   YSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPK 65
           Y++++  E+ G+KV + GWV EV+DLGG+ FI +RDREGIVQ+T P+K V +++FKL  K
Sbjct: 4   YTADVKPEMEGQKVTLYGWVHEVRDLGGLVFILLRDREGIVQITLPRKFVSKQVFKLAKK 63

Query: 66  LNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRF 125
           +  E VI V G V    KA  G EIIPE +EV+++A  PLPL+ T KV AELDTRLD+RF
Sbjct: 64  IRRESVIAVTGEVRREEKAPGGVEIIPESIEVLNEADAPLPLEVTEKVPAELDTRLDHRF 123

Query: 126 MDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDA 185
           MDLR PRV +IF+IR  V ++ REF  +EGFIE+HTPKI++TATEGGTELFP+ YFE +A
Sbjct: 124 MDLRRPRVQAIFRIRHQVMQSVREFLSEEGFIEVHTPKIVSTATEGGTELFPISYFEKEA 183

Query: 186 FLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMD 245
           FL QSPQLYKQ++M+ G +KVFEIGPIFRAEEHNTTRHLNEA SID EM+F +    VMD
Sbjct: 184 FLNQSPQLYKQVLMAAGFEKVFEIGPIFRAEEHNTTRHLNEAISIDIEMSFTD-HNGVMD 242

Query: 246 LLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIPWGEDI 305
           +LERL+  V   V E  E+ L  LE  L  P+ PFPRITYDEA EI +  G+EIPWGED+
Sbjct: 243 VLERLVQRVYEDVAEKCERYLGWLEVSLEIPELPFPRITYDEAREIAARKGEEIPWGEDL 302

Query: 306 DTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSG 365
            T   KL+G+ M       LYFI  +P+E+KPFY M YED+PE+ K+FDL +  +E+SSG
Sbjct: 303 STNALKLVGEEM-----GGLYFITDWPTESKPFYAMPYEDRPEISKSFDLMHGWLELSSG 357

Query: 366 GQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIRE 425
            QR H +D+LVE I+ KG+ PESF FYL AF YGMPPH G+GLGAERLIM ML + N+RE
Sbjct: 358 AQRIHLYDMLVESIKAKGMEPESFGFYLEAFRYGMPPHAGWGLGAERLIMSMLGLKNVRE 417

Query: 426 VILFPRDRRRLVP 438
            +LFPRDR RLVP
Sbjct: 418 AVLFPRDRHRLVP 430


>sp|Q58950|SYD_METJA ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
           >gi|2127776|pir||B64494 aspartate--tRNA ligase (EC
           6.1.1.12) - Methanococcus jannaschii
           >gi|1592183|gb|AAB99575.1| (U67596) aspartyl-tRNA
           synthetase (aspS) [Methanococcus jannaschii]
           Length = 438
           
 Score =  514 bits (1310), Expect = e-145
 Identities = 253/436 (58%), Positives = 324/436 (74%), Gaps = 6/436 (1%)

Query: 3   RTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKL 62
           RTHYS++I  E++G++V + GWV  ++ LG I F+ +RDREG VQ+ APK+KV  E+F  
Sbjct: 9   RTHYSADIKPEMDGQEVIIMGWVHSIRALGKIIFVILRDREGTVQIVAPKQKVGDELFSQ 68

Query: 63  IPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLD 122
           I KL +EDVI V+G V    KA  GFEI+P +LEVI+ AK PLPLDP  KV AELDTRL+
Sbjct: 69  IKKLGAEDVIAVKGKVIANEKAPNGFEILPLELEVINTAKRPLPLDPAEKVPAELDTRLE 128

Query: 123 NRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFE 182
           NRF+DLR P+V +IFKIRS + ++ R   Y EGFIE++TPK++A+ TEGGTELFP+ YFE
Sbjct: 129 NRFLDLRRPKVQAIFKIRSEMLKSVRNTLYNEGFIEVNTPKLVASCTEGGTELFPISYFE 188

Query: 183 NDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEE 242
            +AFL QSPQLYKQM+M+TGLD+VFEI PIFRAEEHNT RHLNEA SID EMAF + +++
Sbjct: 189 REAFLGQSPQLYKQMLMATGLDRVFEIAPIFRAEEHNTRRHLNEATSIDIEMAFAD-DKD 247

Query: 243 VMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIPWG 302
            MD+LE+++      V EN +KE++ L  E   P + F RITYDEA++I +  G EI WG
Sbjct: 248 AMDILEKVVYNAFVDVYENRKKEIETLGIEFELPPEKFDRITYDEAIDIANAKGVEISWG 307

Query: 303 EDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEI 362
           ED+  E EK +G+   E EG  LYFI  +PSE +PFY M  E  P +CKAFDL Y+ +EI
Sbjct: 308 EDLSREAEKAIGE---EMEG--LYFITDWPSEIRPFYTMPDEKNPNICKAFDLMYKDLEI 362

Query: 363 SSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGN 422
           SSG QR H +D+LVE I++KGLNP+ F +YL AF+YGMPPH G+GLGA+R  M +    N
Sbjct: 363 SSGAQRIHLYDLLVENIKKKGLNPDGFTYYLEAFKYGMPPHAGWGLGADRFTMVLTQQEN 422

Query: 423 IREVILFPRDRRRLVP 438
           IRE +LFPRDR+RL P
Sbjct: 423 IRECVLFPRDRQRLTP 438


>sp|O26328|SYD_METTH ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
           >gi|7437592|pir||A69128 aspartate--tRNA ligase (EC
           6.1.1.12) - Methanobacterium thermoautotrophicum (strain
           Delta H) >gi|2621273|gb|AAB84732.1| (AE000809)
           aspartyl-tRNA synthetase [Methanobacterium
           thermoautotrophicum]
           Length = 437
           
 Score =  495 bits (1262), Expect = e-139
 Identities = 246/436 (56%), Positives = 320/436 (72%), Gaps = 6/436 (1%)

Query: 3   RTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKL 62
           RTHYS +I  E++G +V V GWV E++DLGGI F+ +RDR+G++Q+TAP KK+ +++FK 
Sbjct: 8   RTHYSKDIEPEMDGDEVTVMGWVHEIRDLGGIIFVLLRDRDGLIQITAPSKKIEKDLFKS 67

Query: 63  IPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLD 122
           I KL  E V+   G V  + KA  GFEIIP  L+V++ +K PLPLDPT KVKAE+DTRLD
Sbjct: 68  IRKLKKESVVAFGGTVQESGKAPGGFEIIPSFLKVLNISKQPLPLDPTEKVKAEIDTRLD 127

Query: 123 NRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFE 182
            RF+DLR P V +IFKI+S +  + R F  ++GF+EI+TPK++A+ATEGGTELFP+ YFE
Sbjct: 128 ARFLDLRKPSVSAIFKIKSRMLHSVRVFLEEQGFLEINTPKLVASATEGGTELFPITYFE 187

Query: 183 NDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEE 242
            +AFL QSPQLYKQ+MMSTGLD+V+EI PIFRAEEH+T RHLNE  SID E +F++  E+
Sbjct: 188 REAFLGQSPQLYKQIMMSTGLDRVYEIAPIFRAEEHDTLRHLNEVISIDIEASFVD-HED 246

Query: 243 VMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIPWG 302
           VM +LE L++ VI  V E+    L+ L   L  P+ PF R+ YDEA+E+++  G  +  G
Sbjct: 247 VMKILENLVVRVIEDVNEHCTDALETLGRTLEVPETPFERLEYDEAVEMVNSKGVPMKHG 306

Query: 303 EDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEI 362
           ED+    EK LG+ M   +G   YFI  +P+  KPFY+M  ED PE   AFDL YR +EI
Sbjct: 307 EDLPRAAEKALGEIM---DG--YYFITSWPTAIKPFYVMPDEDDPERSHAFDLMYRDLEI 361

Query: 363 SSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGN 422
           SSG  R H+HD+LVE+I+ +GLNP+SFE YL AFEYGMPPH G+GLGAER  M +  + N
Sbjct: 362 SSGAMRVHQHDLLVEKIKRQGLNPDSFESYLSAFEYGMPPHAGWGLGAERFNMTLTGLKN 421

Query: 423 IREVILFPRDRRRLVP 438
           IRE +LFPRDRRRL P
Sbjct: 422 IRETVLFPRDRRRLTP 437


>sp|O24822|SYD_HALVO ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
           >gi|3298338|dbj|BAA31457.1| (AB010464) aspartyl tRNA
           synthetase [Haloferax volcanii]
           Length = 433
           
 Score =  412 bits (1048), Expect = e-114
 Identities = 217/428 (50%), Positives = 289/428 (66%), Gaps = 12/428 (2%)

Query: 16  GKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVE 75
           G  V VAGWV EV+DLGGI F+ +RD  G +QV   K ++  ++ +    ++ E VI V 
Sbjct: 13  GDTVTVAGWVHEVRDLGGIAFLILRDTSGKIQVKFEKDEMDDDLVETGLGVHRESVISVT 72

Query: 76  GIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPRVMS 135
           G V+  P+A  G E+ PE L+VI++A+  LPLDP+GKV AEL TRLDNR +DLR   V +
Sbjct: 73  GEVDEEPRAPTGVEVTPESLDVIAEAEAQLPLDPSGKVDAELSTRLDNRTLDLRKDEVKA 132

Query: 136 IFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFLAQSPQLYK 195
           IF+IR+ V RA R+ F      EI+TPKI+AT TEGGTELFP+ YF  +AF+ QSPQL+K
Sbjct: 133 IFEIRAEVQRAVRDKFRDLRATEINTPKIVATGTEGGTELFPITYFGQEAFMNQSPQLFK 192

Query: 196 QMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYVI 255
           Q+M+ +GL++VFE+GPIFRAEEHNT RHLNEA SID E AFI+   E MD+ E ++    
Sbjct: 193 QLMVGSGLERVFEVGPIFRAEEHNTPRHLNEATSIDFESAFID-HTEAMDVCEAVVTAAY 251

Query: 256 NYVRENNEKELKIL----EFELNEPKKPFPRIT-YDEALEILSDLGKEIPWGEDIDTEGE 310
             V EN + EL+ L    EFE   P+ P   +     A +   +L +++ WG+D+ TEGE
Sbjct: 252 EAVEENCQDELEALGLEEEFE-RRPRVPAAHLRGGHRAHQRTGELDEQLVWGDDLPTEGE 310

Query: 311 KLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSGGQREH 370
           K LG+     +  E YFI  +PSE KPFYI  ++D   +   FD+ +  +E+ SGGQREH
Sbjct: 311 KALGE-----DVGEHYFITDWPSEIKPFYIKDHDDDETLSTGFDMMHPNMELVSGGQREH 365

Query: 371 RHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFP 430
           R D LV    ++GL+P++FE+Y + F+YGMPPH GFGLG ERLIM ML + NIRE +LFP
Sbjct: 366 RFDHLVAGFEQQGLDPDAFEYYTKMFKYGMPPHAGFGLGGERLIMTMLGLENIREAVLFP 425

Query: 431 RDRRRLVP 438
           RDR+RL P
Sbjct: 426 RDRQRLSP 433


>sp|Q9Y9U7|SYD_AERPE ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
           Length = 442
           
 Score =  404 bits (1028), Expect = e-112
 Identities = 198/443 (44%), Positives = 294/443 (65%), Gaps = 6/443 (1%)

Query: 1   MLRTHYSSEIT---EELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQ 57
           ML+  + ++I    E L G +V+V GW   ++DLG +KFI +RDR G++Q T  + + P+
Sbjct: 1   MLKDRFIADIIASKESLVGGRVRVCGWAYRIRDLGRLKFILVRDRSGVIQATVKRGESPE 60

Query: 58  EIFKLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAEL 117
           +  +    L  E V+ VEG +   P  + G E+  E+LEV+S    PLPL+  G  KA L
Sbjct: 61  DALRAAEDLKLESVVCVEGELRQAPTRE-GVEVKVERLEVLSTPVEPLPLEVEGSEKASL 119

Query: 118 DTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFP 177
            TRL  R++D+RNP V +IF++ + V +  R++++ +GF+EI TPKI+A  TE G E+FP
Sbjct: 120 PTRLKYRWLDIRNPMVSAIFELEAMVAKVFRDYYWSQGFVEIFTPKIVAAGTESGAEVFP 179

Query: 178 LKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFI 237
           + YF+  AFLAQSPQ YKQ  +  GL++VFEIGP+FRAE H+T+RHLNE  S+D E+ FI
Sbjct: 180 VVYFDKTAFLAQSPQFYKQFAVIAGLERVFEIGPVFRAEPHHTSRHLNEYHSLDIEVGFI 239

Query: 238 ESEEEVMDLLERLILYVINYVRENNEKELKILEFELNE-PKKPFPRITYDEALEILSD-L 295
           ES  +VM+ +E  +  ++  + E+  + L++   EL   P    P+I   +A EIL +  
Sbjct: 240 ESYNDVMNYVEGFMRAIVRMLEEDGRRVLELYGVELPRIPASGIPKIPLRKAYEILEEKY 299

Query: 296 GKEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDL 355
           GK++ +GED+D+EGE+L+G Y  E   ++  FI  YP + +PFY M+ +D+P    +FDL
Sbjct: 300 GKKVEYGEDLDSEGERLMGAYAGEELDSDFVFIVEYPWKVRPFYTMRKDDEPSWTYSFDL 359

Query: 356 EYRGVEISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIM 415
            YRG+EI +GGQREHR+  L+E +R+KGL+ ESF+FYL  F++G PPHGG G+G ER++M
Sbjct: 360 LYRGLEIVTGGQREHRYHRLLENLRDKGLDAESFQFYLDFFKHGAPPHGGAGMGLERIVM 419

Query: 416 RMLDIGNIREVILFPRDRRRLVP 438
           + L + NIRE  + PRD  R+ P
Sbjct: 420 QTLKLENIREARMLPRDTERITP 442


>pir||C72527 probable aspartyl-tRNA synthetase APE2192 - Aeropyrum pernix
           (strain K1) >gi|5105891|dbj|BAA81203.1| (AP000063) 421aa
           long hypothetical aspartyl-tRNA synthetase [Aeropyrum
           pernix]
           Length = 421
           
 Score =  397 bits (1010), Expect = e-109
 Identities = 191/422 (45%), Positives = 283/422 (66%), Gaps = 3/422 (0%)

Query: 19  VKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVEGIV 78
           ++V GW   ++DLG +KFI +RDR G++Q T  + + P++  +    L  E V+ VEG +
Sbjct: 1   MRVCGWAYRIRDLGRLKFILVRDRSGVIQATVKRGESPEDALRAAEDLKLESVVCVEGEL 60

Query: 79  NFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPRVMSIFK 138
              P  + G E+  E+LEV+S    PLPL+  G  KA L TRL  R++D+RNP V +IF+
Sbjct: 61  RQAPTRE-GVEVKVERLEVLSTPVEPLPLEVEGSEKASLPTRLKYRWLDIRNPMVSAIFE 119

Query: 139 IRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFLAQSPQLYKQMM 198
           + + V +  R++++ +GF+EI TPKI+A  TE G E+FP+ YF+  AFLAQSPQ YKQ  
Sbjct: 120 LEAMVAKVFRDYYWSQGFVEIFTPKIVAAGTESGAEVFPVVYFDKTAFLAQSPQFYKQFA 179

Query: 199 MSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYVINYV 258
           +  GL++VFEIGP+FRAE H+T+RHLNE  S+D E+ FIES  +VM+ +E  +  ++  +
Sbjct: 180 VIAGLERVFEIGPVFRAEPHHTSRHLNEYHSLDIEVGFIESYNDVMNYVEGFMRAIVRML 239

Query: 259 RENNEKELKILEFELNE-PKKPFPRITYDEALEILSD-LGKEIPWGEDIDTEGEKLLGKY 316
            E+  + L++   EL   P    P+I   +A EIL +  GK++ +GED+D+EGE+L+G Y
Sbjct: 240 EEDGRRVLELYGVELPRIPASGIPKIPLRKAYEILEEKYGKKVEYGEDLDSEGERLMGAY 299

Query: 317 MLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSGGQREHRHDILV 376
             E   ++  FI  YP + +PFY M+ +D+P    +FDL YRG+EI +GGQREHR+  L+
Sbjct: 300 AGEELDSDFVFIVEYPWKVRPFYTMRKDDEPSWTYSFDLLYRGLEIVTGGQREHRYHRLL 359

Query: 377 EQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRRRL 436
           E +R+KGL+ ESF+FYL  F++G PPHGG G+G ER++M+ L + NIRE  + PRD  R+
Sbjct: 360 ENLRDKGLDAESFQFYLDFFKHGAPPHGGAGMGLERIVMQTLKLENIREARMLPRDTERI 419

Query: 437 VP 438
            P
Sbjct: 420 TP 421


>emb|CAC12075.1| (AL445066) aspartyl-tRNA synthetase related protein [Thermoplasma
           acidophilum]
           Length = 428
           
 Score =  390 bits (991), Expect = e-107
 Identities = 194/434 (44%), Positives = 286/434 (65%), Gaps = 11/434 (2%)

Query: 6   YSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPK 65
           Y   + +  +G KV V GW+QE + +  I F+ IRD  G +Q T    +   +I K   +
Sbjct: 5   YIDTLRDHEDGAKVVVYGWMQEARIMKNISFLMIRDNTGTIQATFKNDEATLDIIK---R 61

Query: 66  LNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRF 125
           +N E ++ V+G VN    +K G EI    + ++++A+ PLPL     V+A+L+TRL++RF
Sbjct: 62  INRESIVRVDGSVNKKSISKAGIEISGTSISIVNEAEAPLPLPVVDPVQADLETRLNSRF 121

Query: 126 MDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDA 185
           MDLR   + +IF+I S++    R++ + + FIE+HTPKI+A ATEGG++LFP++YFE DA
Sbjct: 122 MDLRKRNISAIFRIESALLWGIRQYLHSQKFIEVHTPKIVAAATEGGSDLFPVRYFEKDA 181

Query: 186 FLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMD 245
           +L QSPQLYK+++MS G D+VFE+GP FRAEEHNTTRHLNE  SID EM+F +   + M 
Sbjct: 182 YLNQSPQLYKEVLMSAGFDRVFEVGPAFRAEEHNTTRHLNEFTSIDIEMSFAD-HNDAMA 240

Query: 246 LLERLILYVI-NYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIPWGED 304
           +LE  I   I N VREN E + + L   ++ P+ PFPRITY++ +++L   G +  +G+D
Sbjct: 241 MLENAIRSGIENAVRENAE-DFESLGISISVPETPFPRITYEQCIDLLQKDGIDFTFGDD 299

Query: 305 IDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISS 364
              +  + +G     +  +  YFI  +PS  +PFY M   + P +  +FDL+YR +E++S
Sbjct: 300 FSPDQLRTIG-----SRFSGFYFITEWPSSVRPFYTMPKSEDPRLTNSFDLQYREIEVTS 354

Query: 365 GGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIR 424
           G QR H   +L+++  EK L+ +SF+FY+ AF+YGMPPH G+GLG ERL M +L + NIR
Sbjct: 355 GAQRVHDPKMLIQRFNEKKLDVKSFQFYVDAFKYGMPPHAGWGLGLERLTMILLGLNNIR 414

Query: 425 EVILFPRDRRRLVP 438
           E  LFPRDR R+VP
Sbjct: 415 ETTLFPRDRTRIVP 428


>gb|AAK40519.1| Aspartyl-tRNA synthetase (aspS) [Sulfolobus solfataricus]
           Length = 429
           
 Score =  383 bits (972), Expect = e-105
 Identities = 191/438 (43%), Positives = 292/438 (66%), Gaps = 9/438 (2%)

Query: 1   MLRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF 60
           M RTH  SE+  +L+G +VKVAGWV  V++LGG  FI +RD+ GI Q+   K       +
Sbjct: 1   MFRTHLVSELNPKLDGSEVKVAGWVHNVRNLGGKIFILLRDKSGIGQIVVEKGN---NAY 57

Query: 61  KLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTR 120
             +  +  E  IVV G+V    +A  G E+  + +E++S A++PLPLD TGKVKA++DTR
Sbjct: 58  DKVINIGLESTIVVNGVVKADARAPNGVEVHAKDIEILSYARSPLPLDVTGKVKADIDTR 117

Query: 121 LDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKY 180
           L  R +DLR   + ++ KI+S   ++ RE  YK GF+E+ TPKIIA+ATEGG +LFP+ Y
Sbjct: 118 LRERLLDLRRLEMQAVLKIQSVAVKSFRETLYKHGFVEVFTPKIIASATEGGAQLFPVLY 177

Query: 181 FENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESE 240
           F  +AFLAQSPQLYK+ +++  +++VFEI P +RAEE +T  HL+E  S+D EMAF +  
Sbjct: 178 FGKEAFLAQSPQLYKE-LLAGAIERVFEIAPAWRAEESDTPYHLSEFISMDVEMAFAD-Y 235

Query: 241 EEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIP 300
            ++M L+E++I  +IN V+   E ELKIL +     + P  +++Y +A+E+L   G  I 
Sbjct: 236 NDIMALIEQIIYNMINDVKRECENELKILNYTPPNVRIPIKKVSYSDAIELLKSKGVNIK 295

Query: 301 WGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGV 360
           +G+DI T   ++L   + E    +LYF+  +P  ++PFY  + +D P++ ++FDL +R +
Sbjct: 296 FGDDIGTPELRVLYNELKE----DLYFVTDWPWLSRPFYTKQKKDNPQLSESFDLIFRWL 351

Query: 361 EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDI 420
           EI SG  R H  ++L   ++ +GLNPESFEF+L+ F+YGMPPH GFG+G  R+++ +  +
Sbjct: 352 EIVSGSSRNHVKEVLENSLKVRGLNPESFEFFLKWFDYGMPPHAGFGMGLARVMLMLTGL 411

Query: 421 GNIREVILFPRDRRRLVP 438
            +++EV+ FPRD++RL P
Sbjct: 412 QSVKEVVPFPRDKKRLTP 429


>sp|O07683|SYD_HALSA ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
           >gi|11271301|pir||T48900 aspartate--tRNA ligase (EC
           6.1.1.12) [imported] - Halobacterium salinarum
           >gi|2209068|dbj|BAA20527.1| (D82887) aspartyl-tRNA
           synthetase [Halobacterium salinarum]
           >gi|10580067|gb|AAG19001.1| (AE005000) aspartyl-tRNA
           synthetase; AspS [Halobacterium sp. NRC-1]
           Length = 436
           
 Score =  370 bits (940), Expect = e-101
 Identities = 186/439 (42%), Positives = 286/439 (64%), Gaps = 4/439 (0%)

Query: 1   MLRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF 60
           ML   Y  ++T + +G+   +AG V E++DLGGI F+ +RD  G +QV A +   P ++F
Sbjct: 1   MLERTYIEDVTPDDDGEDTTIAGHVHELRDLGGILFVIVRDATGRLQVVAKEDDTP-DLF 59

Query: 61  KLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTR 120
           +    L+SEDV+ V G +  + +A  G E+ P +L V+S+A     ++ +  V A+L TR
Sbjct: 60  ETAEGLSSEDVVQVTGTLEASDQAPGGVELAPTELTVVSEATDVPSIEISKDVDADLSTR 119

Query: 121 LDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKY 180
           LD R +D+R P   ++F +RS    A  ++FY   F E+ TP++     EGG +LFP+ Y
Sbjct: 120 LDERHLDVRKPSTKAVFSLRSKAMGAMTDWFYDNRFEEVDTPELSTAGAEGGADLFPVVY 179

Query: 181 FENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESE 240
           ++ +A+L+QSPQLYKQ+++++G+D++FE+G  FRAE+  T+RH++E    D E+ ++E  
Sbjct: 180 YDKEAYLSQSPQLYKQILVASGVDRLFEVGHAFRAEDFGTSRHVSEIAMFDVELGYVEDH 239

Query: 241 EEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIP 300
            +VMD+ E  + + I +V E+ ++EL  L  +L+ P+  FPRIT++EA EIL+D    +P
Sbjct: 240 HDVMDVQEESLRHTIRHVVEHAQRELDELGSDLSVPEADFPRITFEEAREILADEYDHVP 299

Query: 301 WGE-DIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRG 359
             + D+DT+GE+LLG+Y  E +G    F+  YP E K +Y    +      + FDL YRG
Sbjct: 300 EDDNDLDTKGERLLGEY-FEEQGHPAVFVVGYPDE-KFYYRQDVDGDDVASRKFDLLYRG 357

Query: 360 VEISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLD 419
            E+SSGGQREH  + L  ++RE+G+ PE+FEFYL AF YG+PPHGG+GLG +RLI ++  
Sbjct: 358 QELSSGGQREHDIERLTAKMREQGVEPENFEFYLDAFRYGVPPHGGYGLGIDRLIQQLAG 417

Query: 420 IGNIREVILFPRDRRRLVP 438
           + NI+E ILFPRD  RL P
Sbjct: 418 LDNIKEAILFPRDPDRLEP 436


>gb|AAF61689.1| (AF219996) aspartyl-tRNA synthetase 2 [Thermus thermophilus]
           Length = 422
           
 Score =  326 bits (828), Expect = 2e-88
 Identities = 173/425 (40%), Positives = 267/425 (62%), Gaps = 17/425 (4%)

Query: 16  GKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVE 75
           G++V++ G++   +DLG I+F+ +RDR G+VQV     K+P      +P    E  + V 
Sbjct: 13  GQEVELLGFLHWRRDLGRIQFLLLRDRSGVVQVVTGGLKLP------LP----ESALRVR 62

Query: 76  GIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLD-PTGKVKAELDTRLDNRFMDLRNPRVM 134
           G+V    KA  G E+  +++EV+S A  P P++ P  + +A  DT L+ R++ LR  +  
Sbjct: 63  GLVVENAKAPGGLEVQAKEVEVLSPALEPTPVEIPKEEWRANPDTLLEYRYVTLRGEKAR 122

Query: 135 SIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFLAQSPQLY 194
           +  K+++++ R  R +  ++ F EI TPK++    EGG+ LF + YFE  A+LAQSPQLY
Sbjct: 123 APLKVQAALVRGFRRYLDRQDFTEIFTPKVVRAGAEGGSGLFGVDYFEKRAYLAQSPQLY 182

Query: 195 KQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYV 254
           KQ+M+    ++V+E+ P++R EEH+T+RHLNE  S+D EM FI  EE++M L E L+  +
Sbjct: 183 KQIMVGV-FERVYEVAPVWRMEEHHTSRHLNEYLSLDVEMGFIADEEDLMRLEEALLAEM 241

Query: 255 INYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSD-LGKEIPWGEDIDTEGEKLL 313
           +         E+++L        +  PR+T+ EA  IL + LG   P G+D+  E E+LL
Sbjct: 242 LEEALNTAGDEIRLLGATWPSFPQDIPRLTHAEAKRILKEELG--YPVGQDLSEEAERLL 299

Query: 314 GKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSGGQREHRHD 373
           G+Y  E  G++  F+ RYP   +PFY   Y ++    ++FDL +RG+EI+SGGQR HR++
Sbjct: 300 GEYAKERWGSDWLFVTRYPRSVRPFYT--YPEEDGTTRSFDLLFRGLEITSGGQRIHRYE 357

Query: 374 ILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDR 433
            L+E ++ KG++PE+F  YL  F+YGMPPHGGF +GAERL  ++L + N+R    FPRDR
Sbjct: 358 ELLESLKAKGMDPEAFHGYLEVFKYGMPPHGGFAIGAERLTQKLLGLPNVRYARAFPRDR 417

Query: 434 RRLVP 438
            RL P
Sbjct: 418 HRLTP 422


>pir||H75443 aspartyl-tRNA synthetase, non-discriminating - Deinococcus
           radiodurans (strain R1)
           >gi|6458780|gb|AAF10623.1|AE001956_4 (AE001956)
           aspartyl-tRNA synthetase, non-discriminating
           [Deinococcus radiodurans]
           Length = 435
           
 Score =  318 bits (806), Expect = 9e-86
 Identities = 177/438 (40%), Positives = 257/438 (58%), Gaps = 20/438 (4%)

Query: 10  ITEEL---NGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKL 66
           +T EL    G+ VK+ G+V   +DLGG++F+ +RD  G+ Q       +P          
Sbjct: 9   LTRELPQHEGQTVKLQGFVHARRDLGGVQFLVLRDVTGVTQCVGSGLTLPL--------- 59

Query: 67  NSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLD-PTGKVKAELDTRLDNRF 125
            +E  + V G V   PKA  GFE+  E   VIS A    P++ P  +     +T LD R 
Sbjct: 60  -AESSVEVVGKVKAHPKAPGGFEVQVEDFRVISAATEATPVEIPKMEWNVNPETMLDYRV 118

Query: 126 MDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDA 185
           + +R  +  +  K+++ +  A R     EGF EI TPKI++   EGG  LFP+ YF + A
Sbjct: 119 VTVRGLKERAALKVQAELVDAFRAHLRGEGFTEISTPKIVSAGAEGGANLFPIDYFGHPA 178

Query: 186 FLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMD 245
           +LAQSPQLYKQ+M+    ++VFE+  ++RAEEH T+RHLNE  S+D EM FIE EE+VM 
Sbjct: 179 YLAQSPQLYKQIMVGV-FERVFEVAAVYRAEEHATSRHLNEYLSLDVEMGFIEDEEDVMG 237

Query: 246 LLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIPWGEDI 305
           L  RL+  ++  +R  ++ E ++L   + +     PRIT  +A +++++       G+D+
Sbjct: 238 LENRLLASIMERLRATSQAEFELLGATIPDVPAHIPRITLMDARQLVTEKYGHPVGGKDL 297

Query: 306 DTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMK--YED---KPEVCKAFDLEYRGV 360
           D E E+LL ++  E EG++  F+ +YP  A+PFY      ED     EV + FDL +RG+
Sbjct: 298 DPEAERLLSQHFAETEGSDFVFVTKYPRAARPFYAHPELNEDGSVNGEVTRGFDLLFRGI 357

Query: 361 EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDI 420
           EI+SGGQR H + +L++ I    L PES E Y   F+YGMPPHGGF +GAERL  ++L I
Sbjct: 358 EITSGGQRIHDYGMLMDSIAAYKLKPESLEGYTEVFKYGMPPHGGFAIGAERLTAKLLGI 417

Query: 421 GNIREVILFPRDRRRLVP 438
            N+R    FPRDR RL P
Sbjct: 418 ANVRYARAFPRDRHRLTP 435


>pir||D75212 asparagine--tRNA ligase (EC 6.1.1.22) PAB2203 - Pyrococcus abyssi
           (strain Orsay) >gi|5457656|emb|CAB49147.1| (AJ248283)
           ASPARAGINYL-TRNA SYNTHETASE (EC 6.1.1.22)
           (ASPARAGINE--TRNA LIGASE) (ASNRS) [Pyrococcus abyssi]
           Length = 434
           
 Score =  305 bits (772), Expect = 8e-82
 Identities = 170/445 (38%), Positives = 266/445 (59%), Gaps = 18/445 (4%)

Query: 1   MLRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF 60
           M+   Y  +I  EL+GK+VK+AGWV     +G   F+WIRD  GI+Q    K  V +++F
Sbjct: 1   MIEKTYCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVF 60

Query: 61  KLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVI-SKAKTPLPLDPTGKVKAELDT 119
           +   KL  E  ++VEGIV    +A  G E+  EKL+VI + ++ P+P +P    +A  + 
Sbjct: 61  ETAKKLGRESSVIVEGIVKADERAPGGAEVHVEKLKVIQAVSEFPIPENPE---QASPEL 117

Query: 120 RLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLK 179
            LD R + +R+P+V +I +++ ++  A RE+  +EG+ E+  P ++  A EGG  LF LK
Sbjct: 118 LLDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLK 177

Query: 180 YFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIES 239
           YF+  A+L+QS QLY +  +  GL+KV+ + P FRAE+  T RHL E W ++ E A+++ 
Sbjct: 178 YFDKVAYLSQSAQLYLEAAI-FGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDL 236

Query: 240 EEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKK---PFPRITYDEALEILSDLG 296
             ++M + E L+ Y++    E  +KE+++   +L   K    PFPRI+YDEA+EIL   G
Sbjct: 237 -WDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIEILQSKG 295

Query: 297 KEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDL- 355
            +I WG+D+  + E+     +L  E    +F+Y YP   K FY+ +  + P    A D+ 
Sbjct: 296 VKIEWGDDMGADEER-----VLTQEFDRPFFVYGYPKHIKAFYMKEDPNDPRKVLAADML 350

Query: 356 --EYRGVEISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERL 413
             E  G EI  G +RE  +D LV++I+E+G++P+ +E+YL   +YG  PH GFGLG ERL
Sbjct: 351 APEGYG-EIIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERL 409

Query: 414 IMRMLDIGNIREVILFPRDRRRLVP 438
           +  +L + +IR   LFPR   R+ P
Sbjct: 410 VAWVLKLDHIRWATLFPRTPARIYP 434


>pir||B71248 asparagine--tRNA ligase (EC 6.1.1.22) - Pyrococcus horikoshii
           >gi|3256630|dbj|BAA29313.1| (AP000001) 434aa long
           hypothetical asparaginyl-tRNA synthetase [Pyrococcus
           horikoshii]
           Length = 434
           
 Score =  301 bits (763), Expect = 9e-81
 Identities = 172/445 (38%), Positives = 259/445 (57%), Gaps = 18/445 (4%)

Query: 1   MLRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF 60
           M+   Y  E+  EL+GKKV++AGWV     +G   F+WIRD  GIVQ    K  V +E F
Sbjct: 1   MIEKVYCQEVKPELDGKKVRLAGWVYTNMRVGKKIFLWIRDSTGIVQAVVAKNVVGEETF 60

Query: 61  KLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVI-SKAKTPLPLDPTGKVKAELDT 119
           +   KL  E  ++VEGIV    +A  G E+  EKLEVI + ++ P+P +P    +A  + 
Sbjct: 61  EKAKKLGRESSVIVEGIVKADERAPGGAEVHVEKLEVIQAVSEFPIPENPE---QASPEL 117

Query: 120 RLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLK 179
            LD R + +R P+  +I K++ ++  A RE+  K+G+ E+  P ++  A EGG  LF LK
Sbjct: 118 LLDYRHLHIRTPKASAIMKVKETLIMAAREWLLKDGWHEVFPPILVTGAVEGGATLFKLK 177

Query: 180 YFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIES 239
           YF+  A+L+QS QLY +  +  GL+KV+ + P FRAE+  T RHL E W ++ E A+++ 
Sbjct: 178 YFDKYAYLSQSAQLYLEAAI-FGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDL 236

Query: 240 EEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKK---PFPRITYDEALEILSDLG 296
             ++M + E L+ Y++    E  +KE+++   +L   K    PFPRI+YDEA++IL   G
Sbjct: 237 -WDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIDILQSKG 295

Query: 297 KEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDL- 355
             + WG+D+  + E+     +L  E    +F+Y YP   K FY+ +  + P    A D+ 
Sbjct: 296 VNVEWGDDLGADEER-----VLTEEFDRPFFVYGYPKHIKAFYMKEDPNDPRKVLASDML 350

Query: 356 --EYRGVEISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERL 413
             E  G EI  G QRE  +D L+ +I E+G++P+ +E+YL    YG  PH GFGLG ERL
Sbjct: 351 APEGYG-EIIGGSQREDDYDKLLNRILEEGMDPKDYEWYLDLRRYGSVPHSGFGLGVERL 409

Query: 414 IMRMLDIGNIREVILFPRDRRRLVP 438
           +  +L + +IR   LFPR   RL P
Sbjct: 410 VAWVLKLDHIRWAALFPRTPARLYP 434


>pir||T04810 aspartate--tRNA ligase homolog F10M23.210 - Arabidopsis thaliana
           >gi|4455210|emb|CAB36533.1| (AL035440) putative
           aspartate-tRNA ligase [Arabidopsis thaliana]
           >gi|7269540|emb|CAB79542.1| (AL161566) putative
           aspartate-tRNA ligase [Arabidopsis thaliana]
           Length = 504
           
 Score =  292 bits (740), Expect = 5e-78
 Identities = 166/442 (37%), Positives = 253/442 (56%), Gaps = 25/442 (5%)

Query: 8   SEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLN 67
           S + EE+ G +V + G + + + +G   F+ +R+    VQ    + +V   + K + +L+
Sbjct: 77  SNLVEEIVGSEVSIRGRLHKNRLVGTKLFVILRESGFTVQCVVEETRVGANMIKFVKQLS 136

Query: 68  SEDVIVVEGIVNFTPKAKLG----FEIIPEKLEVISKAKTPLPLDPTGKVKAELD----- 118
            E V+ + G+V+   K   G     EI   K+  +S++   LPL      ++E D     
Sbjct: 137 RESVVELIGVVSHPKKPLTGTTQQVEIHVRKMYCLSRSLPNLPLVVEDAARSESDIEKSG 196

Query: 119 --TRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELF 176
             TRL+NR +D+R P   +IF+I+  V  A RE+   +GF+EIHTPK+IA ++EGG+ +F
Sbjct: 197 KDTRLNNRVLDIRTPANQAIFRIQCQVQIAFREYLQSKGFLEIHTPKLIAGSSEGGSAVF 256

Query: 177 PLKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAF 236
            L Y    A LAQSPQL+KQM +   + +VFE+GP+FRAE+  T RHL E   +D EM  
Sbjct: 257 RLDYKGQPACLAQSPQLHKQMAICGDMRRVFEVGPVFRAEDSFTHRHLCEFVGLDVEMEI 316

Query: 237 IESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLG 296
                E+MDL+  L  ++   + E   KEL+ +       +K +P  +  EA E +  LG
Sbjct: 317 RMHYSEIMDLVGELFPFIFTKIEERCPKELESV-------RKQYPFQSLKEAGEEVDPLG 369

Query: 297 KEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLE 356
                  D++TE E+ LG+ +LE    E Y ++RYPS  +PFY M YE+      +FD+ 
Sbjct: 370 -------DLNTESERKLGQLVLEKYKTEFYMLHRYPSAVRPFYTMPYENDSNYSNSFDVF 422

Query: 357 YRGVEISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMR 416
            RG EI SG QR H  ++L ++ RE G++ ++   Y+ AF YG PPHGGFG+G ER++M 
Sbjct: 423 IRGEEIMSGAQRIHDPELLEKRARECGIDVKTISTYIDAFRYGAPPHGGFGVGLERVVML 482

Query: 417 MLDIGNIREVILFPRDRRRLVP 438
           +  + NIR+  LFPRD +RL P
Sbjct: 483 LCALNNIRKTSLFPRDSQRLTP 504


>emb|CAC11659.1| (AL445064) probable asparaginyl--tRNA synthetase [Thermoplasma
           acidophilum]
           Length = 429
           
 Score =  281 bits (711), Expect = 1e-74
 Identities = 158/433 (36%), Positives = 250/433 (57%), Gaps = 17/433 (3%)

Query: 11  TEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSED 70
           T+   G KV + GWV  ++  GG+ F+ +RD  GI+Q TA K ++P++++  I  L  E 
Sbjct: 9   TKAYVGSKVSIRGWVYRIRSSGGVTFVVVRDSSGIIQCTARKNELPEDVYDTISSLGIES 68

Query: 71  VIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRN 130
            +   G +    ++  G+EI  +   V  K      + P  K + E +  LDNR + LR+
Sbjct: 69  SVEFHGTLKEDRRSPSGYEIAVDSFRVYQKND----VFPITKDQGE-EFLLDNRHLWLRS 123

Query: 131 PRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFLAQS 190
               S+ KIRS++FR+  +FFY+ G+ ++ TP +++TA EGG+ LF + +F    +L QS
Sbjct: 124 REFTSVLKIRSTIFRSFADFFYENGYYQVQTPFMVSTAVEGGSTLFKVDFFGEPIYLNQS 183

Query: 191 PQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERL 250
            Q Y + M+ + L+KVF I P FRAE+  T RHL E W  +AE+A+I++  E+MD+ ER+
Sbjct: 184 AQFYLETMIYS-LEKVFTIAPSFRAEKSRTRRHLTEYWHAEAEVAWIDN-NEMMDIEERM 241

Query: 251 ILYVINYVRENNEKELKILEFE---LNEPKKPFPRITYDEALEILSDLGKEIPWGEDIDT 307
           I Y+++ V E+NE ELK+L  +   L   K PFPRI Y E +++ + +G  + +G+D+  
Sbjct: 242 IYYIVSRVTEDNEDELKMLNRDPEVLKAMKPPFPRIRYSEIIKVANSIGLPLKYGDDLGA 301

Query: 308 EGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKP-EVCKAFDLEYRGV-EISSG 365
           + E+      +  +     F+  YP + KPFY+    + P EV     L   G  EI  G
Sbjct: 302 DEER-----QITMKYDRPIFVTNYPKDLKPFYMPVDPENPGEVLNHDMLAPEGYGEIIGG 356

Query: 366 GQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIRE 425
            QR   +D L+++IRE  L+  ++ +Y+   +YG  PH GFGLG +RL M ++ + NIRE
Sbjct: 357 SQRIWNYDELMQRIREANLDESAYYWYVDLRKYGSVPHSGFGLGLDRLAMWIMHLDNIRE 416

Query: 426 VILFPRDRRRLVP 438
            I +PR  RR  P
Sbjct: 417 AIPYPRTIRRTKP 429


>gi|4557513 aspartyl-tRNA synthetase [Homo sapiens]
           >gi|135098|sp|P14868|SYD_HUMAN ASPARTYL-TRNA SYNTHETASE
           (ASPARTATE--TRNA LIGASE) (ASPRS) >gi|68530|pir||SYHUDT
           aspartate--tRNA ligase (EC 6.1.1.12) [similarity] -
           human >gi|179102|gb|AAA35567.1| (J05032) aspartyl-tRNA
           synthetase [Homo sapiens]
           Length = 500
           
 Score =  276 bits (699), Expect = 3e-73
 Identities = 158/426 (37%), Positives = 240/426 (56%), Gaps = 24/426 (5%)

Query: 36  FIWIRDREGIVQ-VTAPKKKVPQEIFKLIPKLNSEDVIVVEGIVNFTPKAKLG------F 88
           F+ +R ++  VQ + A      +++ K    +N E ++ VEG+V    + K+G       
Sbjct: 76  FLVLRQQQFNVQALVAVGDHASKQMVKFAANINKESIVDVEGVVRKVNQ-KIGSCTQQDV 134

Query: 89  EIIPEKLEVISKAKTPLPL------------DPTGKVKAELDTRLDNRFMDLRNPRVMSI 136
           E+  +K+ VIS A+  LPL            +  G+     DTRLDNR +DLR     ++
Sbjct: 135 ELHVQKIYVISLAEPRLPLQLDDAVRPEQEGEEEGRATVNQDTRLDNRVIDLRTSTSQAV 194

Query: 137 FKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFLAQSPQLYKQ 196
           F+++S +    RE    +GF+EI TPKII+ A+EGG  +F + YF+N+A+LAQSPQLYKQ
Sbjct: 195 FRLQSGICHLFRETLINKGFVEIQTPKIISAASEGGANVFTVSYFKNNAYLAQSPQLYKQ 254

Query: 197 MMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYVIN 256
           M +    +KVF IGP+FRAE+ NT RHL E   +D EMAF     EVM+ +   ++ +  
Sbjct: 255 MCICADFEKVFSIGPVFRAEDSNTHRHLTEFVGLDIEMAFNYHYHEVMEEIADTMVQIFK 314

Query: 257 YVRENNEKELKILEFELN-EPKK---PFPRITYDEALEILSDLGKEIPWGEDIDTEGEKL 312
            ++E  + E++ +  +   EP K   P  R+ Y EAL +L + G E+   +D+ T  EKL
Sbjct: 315 GLQERFQTEIQTVNKQFPCEPFKFLEPTLRLEYCEALAMLREAGVEMGDEDDLSTPNEKL 374

Query: 313 LGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSGGQREHRH 372
           LG  + E    + Y + +YP   +PFY M     P+  K++D+  RG EI SG QR H  
Sbjct: 375 LGHLVKEKYDTDFYILDKYPLAVRPFYTMPDPRNPKQSKSYDMFMRGEEILSGAQRIHDP 434

Query: 373 DILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRD 432
            +L E+    G + E  + Y+ +F +G PPH G G+G ER+ M  L + N+R+  +FPRD
Sbjct: 435 QLLTERALHHGNDLEKIKAYIDSFRFGAPPHAGGGIGLERVTMLFLGLHNVRQTSMFPRD 494

Query: 433 RRRLVP 438
            +RL P
Sbjct: 495 PKRLTP 500


>gi|6323011 Aspartyl-tRNA synthetase, cytosolic; Dps1p [Saccharomyces
           cerevisiae] >gi|135100|sp|P04802|SYDC_YEAST
           ASPARTYL-TRNA SYNTHETASE, CYTOPLASMIC (ASPARTATE--TRNA
           LIGASE) (ASPRS) >gi|68532|pir||SYBYDC aspartate--tRNA
           ligase (EC 6.1.1.12), cytosolic [validated] - yeast
           (Saccharomyces cerevisiae) >gi|3370|emb|CAA27269.1|
           (X03606) AspRS (aa 1-557) [Saccharomyces cerevisiae]
           >gi|3411|emb|CAA29865.1| (X06665) aspartyl tRNA synthase
           [Saccharomyces cerevisiae] >gi|1297012|emb|CAA66172.1|
           (X97560) aspartyl-tRNA synthetase [Saccharomyces
           cerevisiae] >gi|1360191|emb|CAA97464.1| (Z73123) ORF
           YLL018c [Saccharomyces cerevisiae]
           Length = 557
           
 Score =  275 bits (696), Expect = 7e-73
 Identities = 165/451 (36%), Positives = 244/451 (53%), Gaps = 29/451 (6%)

Query: 17  KKVKVAGWVQEVKDLGG-IKFIWIRDREGIVQVTAPKKK---VPQEIFKLIPKLNSEDVI 72
           K+V     V   +  G  + F+ +R +  ++Q      K   + + + K    LN E ++
Sbjct: 107 KEVLFRARVHNTRQQGATLAFLTLRQQASLIQGLVKANKEGTISKNMVKWAGSLNLESIV 166

Query: 73  VVEGIVNFTPK-----AKLGFEIIPEKLEVISKAKTPLP--LDPTGKVKAE--------- 116
           +V GIV    +          EI   K+  IS+    LP  L+   + +AE         
Sbjct: 167 LVRGIVKKVDEPIKSATVQNLEIHITKIYTISETPEALPILLEDASRSEAEAEAAGLPVV 226

Query: 117 -LDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTEL 175
            LDTRLD R +DLR     +IF+I++ V    RE+   + F E+HTPK++   +EGG+ +
Sbjct: 227 NLDTRLDYRVIDLRTVTNQAIFRIQAGVCELFREYLATKKFTEVHTPKLLGAPSEGGSSV 286

Query: 176 FPLKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMA 235
           F + YF+  A+LAQSPQ  KQ ++    ++V+EIGP+FRAE  NT RH+ E   +D EMA
Sbjct: 287 FEVTYFKGKAYLAQSPQFNKQQLIVADFERVYEIGPVFRAENSNTHRHMTEFTGLDMEMA 346

Query: 236 FIESEEEVMDLLERLILYVINYV--RENNEKELKILEFELNEPKKP----FPRITYDEAL 289
           F E   EV+D L  L +++ + +  R  +E EL   ++ + E K P      R+TY E +
Sbjct: 347 FEEHYHEVLDTLSELFVFIFSELPKRFAHEIELVRKQYPVEEFKLPKDGKMVRLTYKEGI 406

Query: 290 EILSDLGKEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEV 349
           E+L   GKEI   ED+ TE EK LGK + +    + Y + ++P E +PFY M     P+ 
Sbjct: 407 EMLRAAGKEIGDFEDLSTENEKFLGKLVRDKYDTDFYILDKFPLEIRPFYTMPDPANPKY 466

Query: 350 CKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPE--SFEFYLRAFEYGMPPHGGFG 407
             ++D   RG EI SG QR H H +L E+++  GL+PE    + Y   F YG PPH G G
Sbjct: 467 SNSYDFFMRGEEILSGAQRIHDHALLQERMKAHGLSPEDPGLKDYCDGFSYGCPPHAGGG 526

Query: 408 LGAERLIMRMLDIGNIREVILFPRDRRRLVP 438
           +G ER++M  LD+ NIR   LFPRD +RL P
Sbjct: 527 IGLERVVMFYLDLKNIRRASLFPRDPKRLRP 557


>pdb|1ASZ|A Chain A, Aspartyl Trna Synthetase (Asprs) (E.C.6.1.1.12) Complexed
           With Transfer Ribonucleic Acid (Trnaasp) And Atp
           >gi|1064988|pdb|1ASZ|B Chain B, Aspartyl Trna Synthetase
           (Asprs) (E.C.6.1.1.12) Complexed With Transfer
           Ribonucleic Acid (Trnaasp) And Atp
           >gi|1064982|pdb|1ASY|A Chain A, Aspartyl Trna Synthetase
           (Asprs) (E.C.6.1.1.12) Complexed With Transfer
           Ribonucleic Acid (Trnaasp) >gi|1064984|pdb|1ASY|B Chain
           B, Aspartyl Trna Synthetase (Asprs) (E.C.6.1.1.12)
           Complexed With Transfer Ribonucleic Acid (Trnaasp)
           Length = 490
           
 Score =  275 bits (696), Expect = 7e-73
 Identities = 165/451 (36%), Positives = 244/451 (53%), Gaps = 29/451 (6%)

Query: 17  KKVKVAGWVQEVKDLGG-IKFIWIRDREGIVQVTAPKKK---VPQEIFKLIPKLNSEDVI 72
           K+V     V   +  G  + F+ +R +  ++Q      K   + + + K    LN E ++
Sbjct: 40  KEVLFRARVHNTRQQGATLAFLTLRQQASLIQGLVKANKEGTISKNMVKWAGSLNLESIV 99

Query: 73  VVEGIVNFTPK-----AKLGFEIIPEKLEVISKAKTPLP--LDPTGKVKAE--------- 116
           +V GIV    +          EI   K+  IS+    LP  L+   + +AE         
Sbjct: 100 LVRGIVKKVDEPIKSATVQNLEIHITKIYTISETPEALPILLEDASRSEAEAEAAGLPVV 159

Query: 117 -LDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTEL 175
            LDTRLD R +DLR     +IF+I++ V    RE+   + F E+HTPK++   +EGG+ +
Sbjct: 160 NLDTRLDYRVIDLRTVTNQAIFRIQAGVCELFREYLATKKFTEVHTPKLLGAPSEGGSSV 219

Query: 176 FPLKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMA 235
           F + YF+  A+LAQSPQ  KQ ++    ++V+EIGP+FRAE  NT RH+ E   +D EMA
Sbjct: 220 FEVTYFKGKAYLAQSPQFNKQQLIVADFERVYEIGPVFRAENSNTHRHMTEFTGLDMEMA 279

Query: 236 FIESEEEVMDLLERLILYVINYV--RENNEKELKILEFELNEPKKP----FPRITYDEAL 289
           F E   EV+D L  L +++ + +  R  +E EL   ++ + E K P      R+TY E +
Sbjct: 280 FEEHYHEVLDTLSELFVFIFSELPKRFAHEIELVRKQYPVEEFKLPKDGKMVRLTYKEGI 339

Query: 290 EILSDLGKEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEV 349
           E+L   GKEI   ED+ TE EK LGK + +    + Y + ++P E +PFY M     P+ 
Sbjct: 340 EMLRAAGKEIGDFEDLSTENEKFLGKLVRDKYDTDFYILDKFPLEIRPFYTMPDPANPKY 399

Query: 350 CKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPE--SFEFYLRAFEYGMPPHGGFG 407
             ++D   RG EI SG QR H H +L E+++  GL+PE    + Y   F YG PPH G G
Sbjct: 400 SNSYDFFMRGEEILSGAQRIHDHALLQERMKAHGLSPEDPGLKDYCDGFSYGCPPHAGGG 459

Query: 408 LGAERLIMRMLDIGNIREVILFPRDRRRLVP 438
           +G ER++M  LD+ NIR   LFPRD +RL P
Sbjct: 460 IGLERVVMFYLDLKNIRRASLFPRDPKRLRP 490


>pdb|1EOV|A Chain A, Free Aspartyl-Trna Synthetase (Asprs) (E.C. 6.1.1.12) From
           Yeast
           Length = 487
           
 Score =  275 bits (696), Expect = 7e-73
 Identities = 165/451 (36%), Positives = 244/451 (53%), Gaps = 29/451 (6%)

Query: 17  KKVKVAGWVQEVKDLGG-IKFIWIRDREGIVQVTAPKKK---VPQEIFKLIPKLNSEDVI 72
           K+V     V   +  G  + F+ +R +  ++Q      K   + + + K    LN E ++
Sbjct: 37  KEVLFRARVHNTRQQGATLAFLTLRQQASLIQGLVKANKEGTISKNMVKWAGSLNLESIV 96

Query: 73  VVEGIVNFTPK-----AKLGFEIIPEKLEVISKAKTPLP--LDPTGKVKAE--------- 116
           +V GIV    +          EI   K+  IS+    LP  L+   + +AE         
Sbjct: 97  LVRGIVKKVDEPIKSATVQNLEIHITKIYTISETPEALPILLEDASRSEAEAEAAGLPVV 156

Query: 117 -LDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTEL 175
            LDTRLD R +DLR     +IF+I++ V    RE+   + F E+HTPK++   +EGG+ +
Sbjct: 157 NLDTRLDYRVIDLRTVTNQAIFRIQAGVCELFREYLATKKFTEVHTPKLLGAPSEGGSSV 216

Query: 176 FPLKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMA 235
           F + YF+  A+LAQSPQ  KQ ++    ++V+EIGP+FRAE  NT RH+ E   +D EMA
Sbjct: 217 FEVTYFKGKAYLAQSPQFNKQQLIVADFERVYEIGPVFRAENSNTHRHMTEFTGLDMEMA 276

Query: 236 FIESEEEVMDLLERLILYVINYV--RENNEKELKILEFELNEPKKP----FPRITYDEAL 289
           F E   EV+D L  L +++ + +  R  +E EL   ++ + E K P      R+TY E +
Sbjct: 277 FEEHYHEVLDTLSELFVFIFSELPKRFAHEIELVRKQYPVEEFKLPKDGKMVRLTYKEGI 336

Query: 290 EILSDLGKEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEV 349
           E+L   GKEI   ED+ TE EK LGK + +    + Y + ++P E +PFY M     P+ 
Sbjct: 337 EMLRAAGKEIGDFEDLSTENEKFLGKLVRDKYDTDFYILDKFPLEIRPFYTMPDPANPKY 396

Query: 350 CKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPE--SFEFYLRAFEYGMPPHGGFG 407
             ++D   RG EI SG QR H H +L E+++  GL+PE    + Y   F YG PPH G G
Sbjct: 397 SNSYDFFMRGEEILSGAQRIHDHALLQERMKAHGLSPEDPGLKDYCDGFSYGCPPHAGGG 456

Query: 408 LGAERLIMRMLDIGNIREVILFPRDRRRLVP 438
           +G ER++M  LD+ NIR   LFPRD +RL P
Sbjct: 457 IGLERVVMFYLDLKNIRRASLFPRDPKRLRP 487


>gi|11429379 aspartyl-tRNA synthetase [Homo sapiens]
           Length = 484
           
 Score =  275 bits (696), Expect = 7e-73
 Identities = 157/426 (36%), Positives = 239/426 (55%), Gaps = 24/426 (5%)

Query: 36  FIWIRDREGIVQ-VTAPKKKVPQEIFKLIPKLNSEDVIVVEGIVNFTPKAKLG------F 88
           F+ +R ++  VQ + A      +++ K    +N E ++ VEG+V    + K+G       
Sbjct: 60  FLVLRQQQFNVQALVAVGDHASKQMVKFAANINKESIVDVEGVVRKVNQ-KIGSCTQQDV 118

Query: 89  EIIPEKLEVISKAKTPLPL------------DPTGKVKAELDTRLDNRFMDLRNPRVMSI 136
           E+  +K+ VIS A+  LPL            +  G+     DTRLDNR +DLR     ++
Sbjct: 119 ELHVQKIYVISLAEPRLPLQLDDAVRPEAEGEEEGRATVNQDTRLDNRVIDLRTSTSQAV 178

Query: 137 FKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFLAQSPQLYKQ 196
           F+++S +    RE    +GF+EI TPKII+ A+EGG  +F + YF+N+A+LAQSPQLYKQ
Sbjct: 179 FRLQSGICHLFRETLINKGFVEIQTPKIISAASEGGANVFTVSYFKNNAYLAQSPQLYKQ 238

Query: 197 MMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYVIN 256
           M +    +KVF IGP+FRAE+ NT RHL E   +D EMAF     EVM+ +   ++ +  
Sbjct: 239 MCICADFEKVFSIGPVFRAEDSNTHRHLTEFVGLDIEMAFNYHYHEVMEEIADTMVQIFK 298

Query: 257 YVRENNEKELKILEFELN-EPKK---PFPRITYDEALEILSDLGKEIPWGEDIDTEGEKL 312
            ++E  + E++ +  +   EP K   P  R+ Y EAL +L + G E+   +D+ T  EKL
Sbjct: 299 GLQERFQTEIQTVNKQFPCEPFKFLEPTLRLEYCEALAMLREAGVEMGDEDDLSTPNEKL 358

Query: 313 LGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSGGQREHRH 372
           LG  + E    + Y + +YP   +PFY M     P+   ++D+  RG EI SG QR H  
Sbjct: 359 LGHLVKEKYDTDFYILDKYPLAVRPFYTMPDPRNPKQSNSYDMFMRGEEILSGAQRIHDP 418

Query: 373 DILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRD 432
            +L E+    G + E  + Y+ +F +G PPH G G+G ER+ M  L + N+R+  +FPRD
Sbjct: 419 QLLTERALHHGTDLEKIKAYIDSFRFGAPPHAGGGIGLERVTMLFLGLHNVRQTSMFPRD 478

Query: 433 RRRLVP 438
            +RL P
Sbjct: 479 PKRLTP 484


>sp|P15178|SYD_RAT ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
           >gi|68531|pir||SYRTDT aspartate--tRNA ligase (EC
           6.1.1.12) - rat >gi|203066|gb|AAA40789.1| (J04487)
           aspartyl-tRNA synthetase [Rattus norvegicus]
           >gi|1773257|gb|AAC52981.1| (U30812) aspartyl-tRNA
           synthetase [Rattus norvegicus]
           Length = 501
           
 Score =  275 bits (695), Expect = 9e-73
 Identities = 164/453 (36%), Positives = 250/453 (54%), Gaps = 24/453 (5%)

Query: 9   EITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQ-VTAPKKKVPQEIFKLIPKLN 67
           ++T +   + V V   V   +  G   F+ +R ++  VQ + A      +++ K    +N
Sbjct: 50  DLTVQKADEVVWVRARVHTSRAKGKQCFLVLRQQQFNVQALVAVGDHASKQMVKFAANIN 109

Query: 68  SEDVIVVEGIVNFTPKAKLG------FEIIPEKLEVISKAKTPLPL------------DP 109
            E +I VEGIV    + K+G       E+  +K+ VIS A+  LPL            + 
Sbjct: 110 KESIIDVEGIVRKVNQ-KIGSCTQQDVELHVQKIYVISLAEPRLPLQLDDAIRPEVEGEE 168

Query: 110 TGKVKAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATAT 169
            G+     DTRLDNR +DLR     +IF ++S +    RE    +GF+EI TPKII+ A+
Sbjct: 169 DGRATVNQDTRLDNRIIDLRTSTSQAIFHLQSGICHLFRETLINKGFVEIQTPKIISAAS 228

Query: 170 EGGTELFPLKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWS 229
           EGG  +F + YF+++A+LAQSPQLYKQM +    +KVF IGP+FRAE+ NT RHL E   
Sbjct: 229 EGGANVFTVSYFKSNAYLAQSPQLYKQMCICADFEKVFCIGPVFRAEDSNTHRHLTEFVG 288

Query: 230 IDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELN-EPKK---PFPRITY 285
           +D EMAF     EV++ +   ++ +   ++E  + E++ +  +   EP K   P  R+ Y
Sbjct: 289 LDIEMAFNYHYHEVVEEIADTLVQIFKGLQERFQTEIQTVNKQFPCEPFKFLEPTLRLEY 348

Query: 286 DEALEILSDLGKEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYED 345
            EAL +L + G E+   ED+ T  EKLLG+ + E    + Y + +YP   +PFY M    
Sbjct: 349 CEALAMLREAGVEMDDEEDLSTPNEKLLGRLVKEKYDTDFYVLDKYPLAVRPFYTMPDPR 408

Query: 346 KPEVCKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGG 405
            P+   ++D+  RG EI SG QR H   +L E+    G++ E  + Y+ +F +G PPH G
Sbjct: 409 NPKQSNSYDMFMRGEEILSGAQRIHDPQLLTERALHHGIDLEKIKAYIDSFRFGAPPHAG 468

Query: 406 FGLGAERLIMRMLDIGNIREVILFPRDRRRLVP 438
            G+G ER+ M  L + N+R+  +FPRD +RL P
Sbjct: 469 GGIGLERVTMLFLGLHNVRQTSMFPRDPKRLTP 501


>sp|P39772|SYN_BACSU ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRNA LIGASE) (ASNRS)
           >gi|7437578|pir||B69591 asparagine--tRNA ligase (EC
           6.1.1.22) asnS - Bacillus subtilis
           >gi|1146247|gb|AAB38455.1| (L47709) asparaginyl-tRNA
           synthetase [Bacillus subtilis]
           >gi|2634654|emb|CAB14152.1| (Z99115) asparaginyl-tRNA
           synthetase [Bacillus subtilis]
           Length = 430
           
 Score =  275 bits (695), Expect = 9e-73
 Identities = 161/430 (37%), Positives = 243/430 (56%), Gaps = 19/430 (4%)

Query: 16  GKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVE 75
           G++V +  WV   +  G I F+ +RD  G +Q    K +V + IF+    +  E  + ++
Sbjct: 13  GEEVTIGAWVANKRSSGKIAFLQLRDGTGFIQGVVVKAEVEESIFQTAKSVTQETSLYIK 72

Query: 76  GIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPRVMS 135
           GIV    ++ LG+E+    +EVI +A T  P+ P    +   +  +D+R + LR+ R  +
Sbjct: 73  GIVKEDERSPLGYELAVTDIEVIHEA-TDYPITPK---EHGTEFLMDHRHLWLRSKRQHA 128

Query: 136 IFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFLAQSPQLYK 195
           I KIR+ + RAT EFF  EGF+++  P +  +A EG TELF  KYF+ DA+L+QS QLY 
Sbjct: 129 IMKIRNEIIRATYEFFNNEGFVKVDPPILTGSAPEGTTELFATKYFDEDAYLSQSGQLYM 188

Query: 196 QMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYVI 255
           +   +  L KVF  GP FRAE+  T RHL E W I+ EMAF+E EE  + + E  + +++
Sbjct: 189 E-AAAMALGKVFSFGPTFRAEKSKTKRHLIEFWMIEPEMAFVEFEEN-LQVQENYVSFIV 246

Query: 256 NYVRENNEKELKIL---EFELNEPKKPFPRITYDEALEILSDLG-KEIPWGEDIDTEGEK 311
             V +N + EL  L     +L + K PFPRITYDEA+E L + G  +I WG+D     E 
Sbjct: 247 QSVLKNCKIELNTLGRDTSKLEQIKAPFPRITYDEAIEFLKEKGFDDIEWGDDFGAPHET 306

Query: 312 LLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDL---EYRGVEISSGGQR 368
            + ++       +  FI RYP+  KPFY+    D+ +V    DL   E  G EI  G +R
Sbjct: 307 AIAEHY-----DKPVFITRYPTSLKPFYMQPASDREDVVLCADLIAPEGYG-EIIGGSER 360

Query: 369 EHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVIL 428
            H  ++L  +++E GL+ +++++Y    +YG  PH GFGLG ER +  +    ++RE I 
Sbjct: 361 IHDMELLESRLKEHGLDSDAYKWYAELRKYGSVPHSGFGLGLERTVAWISGAPHVRETIP 420

Query: 429 FPRDRRRLVP 438
           FPR   RL P
Sbjct: 421 FPRLLNRLYP 430


>pir||T40867 aspartate--tRNA ligase (EC 6.1.1.12) [similarity] - fission yeast
           (Schizosaccharomyces pombe) >gi|3618213|emb|CAA20876.1|
           (AL031579) aspartyl-trna synthetase, cytoplasmic
           [Schizosaccharomyces pombe]
           Length = 580
           
 Score =  273 bits (692), Expect = 2e-72
 Identities = 165/485 (34%), Positives = 260/485 (53%), Gaps = 54/485 (11%)

Query: 8   SEITEELNGKKVKVAGWVQEVKDLGG-IKFIWIRDREGIVQVTAPKKK--VPQEIFKLIP 64
           S+I+ + +G+ V +   V   +  G  + F  +R +   +Q  A   K  + +++ K   
Sbjct: 96  SDISAKNDGQTVLLRARVYTSRLQGNKMCFFSLRQKYDTIQALAVVNKDTISKQMVKWCG 155

Query: 65  KLNSEDVIVVEGIVNFTPK-----AKLGFEIIPEKLEVISKAKTPLP--LDPTGK----- 112
            ++ E +++VEGIV  +P+          EI    + VIS  K  LP  ++  G+     
Sbjct: 156 SISLESIVLVEGIVKKSPEIIKSATVQDAEIHISSIYVISPIKKNLPFLVEDAGRSEEQI 215

Query: 113 --------------VKAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIE 158
                         V+  LDTRLDNR +DLR P   +IF I++ + +A REF     F E
Sbjct: 216 RESEENAAEGDSKFVRVNLDTRLDNRVLDLRTPTNQAIFDIQAGICQAFREFLLSNSFNE 275

Query: 159 IHTPKIIATATEGGTELFPLKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEH 218
           IHTPK+   ++EGG+ +F ++YF+ D FL+QSPQLYKQM+++   ++VFEIGP+FRAE+ 
Sbjct: 276 IHTPKMSGASSEGGSNVFKIQYFKTDGFLSQSPQLYKQMLIAADRERVFEIGPVFRAEDS 335

Query: 219 NTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKK 278
           NT RH+ E   +D EMAF E   EVM+ +E+L LY+   +RE   K++ ++  +      
Sbjct: 336 NTYRHMTEFTGLDLEMAFNEHYHEVMEFIEKLFLYIFKTIREKYAKQVAVVRQQYPSEDF 395

Query: 279 PFP-----RITYDEALEILSDLGK-------------------EIPWGEDIDTEGEKLLG 314
             P     R  + +A+++L + G                    E P  +D  T  E+ LG
Sbjct: 396 ILPDADRIRFHFKDAVKLLKEAGYRKQLVPGQKVPEDEEFHYCEDPEFDDFSTPEERALG 455

Query: 315 KYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSGGQREHRHDI 374
           + + E    + Y I +YPS  +PFY M   + P    ++D   +G EI SG QR H  ++
Sbjct: 456 QIVREKYHTDFYVIDKYPSSVRPFYTMPDPEDPRYSNSYDFFMKGQEIMSGAQRIHDPEL 515

Query: 375 LVEQIREKGLNPE-SFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDR 433
           LVE+++  G++P+   + Y+ AF  G PPH G G+G ER++M  L++ NIR    FPRD 
Sbjct: 516 LVERMKALGVSPDVGLQQYIDAFAIGCPPHAGGGIGLERVVMFYLNLPNIRLASSFPRDP 575

Query: 434 RRLVP 438
           +RL+P
Sbjct: 576 KRLLP 580


>pir||T10672 aspartate--tRNA ligase homolog F6E21.100 - Arabidopsis thaliana
           >gi|7270020|emb|CAB79836.1| (AL161578) aspartate--tRNA
           ligase-like protein [Arabidopsis thaliana]
           Length = 558
           
 Score =  273 bits (690), Expect = 3e-72
 Identities = 163/460 (35%), Positives = 254/460 (54%), Gaps = 29/460 (6%)

Query: 8   SEITEELNGKKVKVAGWVQEVKDLGG-IKFIWIRDREGIVQVT---APKKKVPQEIFKLI 63
           S++ EE+   +V + G V   +     + F+ +R+    VQ     + K KV   + K +
Sbjct: 99  SDLVEEMLESEVLIRGRVHTNRPTSNKLGFVVLRESGSTVQCVVSQSEKTKVGANMVKYL 158

Query: 64  PKLNSEDVIVVEGIVNFTPKAKLG----FEIIPEKLEVISKAKTPLPLD----------- 108
            +L+ E  + V G+V    +   G     EI   K+  I+K+   LPL            
Sbjct: 159 KQLSRESFVDVIGVVTLPKEPLTGTTQQVEIQVRKVYCINKSLAKLPLSVEDAARSEADI 218

Query: 109 ------PTGKVKAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTP 162
                 P+   +   DTRL+ R +DLR P   +IF+++  V  A RE    + F+ IHTP
Sbjct: 219 EASLQTPSPAARVNQDTRLNYRVLDLRTPANQAIFQLQYEVEYAFREKLRFKNFVGIHTP 278

Query: 163 KIIATATEGGTELFPLKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTR 222
           K++A ++EGG+ +F L+Y    A LAQSPQL+KQM +   L +VFE+GP+FRAE+  T R
Sbjct: 279 KLMAGSSEGGSAVFRLEYKGQPACLAQSPQLHKQMAICGDLRRVFEVGPVFRAEDSFTHR 338

Query: 223 HLNEAWSIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELN-EPKKPFP 281
           HL E   +D EM   +   E+MDL++ L +++   + E  +KEL+ +  +   EP K  P
Sbjct: 339 HLCEFVGLDVEMEIRKHYSEIMDLVDELFVFIFTSLNERCKKELQAVGKQYPFEPLKFLP 398

Query: 282 ---RITYDEALEILSDLGKEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPF 338
              R+T++E +++L + G E+    D++TE E+ LG+ +LE    E Y ++RYP   +PF
Sbjct: 399 KTLRLTFEEGVQMLKEAGVEVDPLGDLNTESERKLGQLVLEKYNTEFYILHRYPKAVRPF 458

Query: 339 YIMKYEDKPEVCKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEY 398
           Y M   D P    +FD+  RG EI SG QR H  ++L ++  E G++ ++   Y+ +F Y
Sbjct: 459 YTMTCADNPLYSNSFDVFIRGEEIISGAQRVHIPEVLEQRAGECGIDVKTISTYIDSFRY 518

Query: 399 GMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRRRLVP 438
           G P HGGFG+G ER++M    + NIR+  LFPRD +RL P
Sbjct: 519 GAPLHGGFGVGLERVVMLFCALNNIRKTSLFPRDPQRLSP 558


>gb|AAF58445.1| (AE003820) Aats-asp gene product [Drosophila melanogaster]
           Length = 531
           
 Score =  265 bits (671), Expect = 6e-70
 Identities = 157/457 (34%), Positives = 245/457 (53%), Gaps = 29/457 (6%)

Query: 8   SEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQ-VTAPKKKVPQEIFKLIPKL 66
           SE++ ++    V V G V   +  G   F+ +R +   VQ + A    + +++ K    +
Sbjct: 78  SELSGQVGKGLVWVRGRVHTSRAKGKQCFLILRQQSSTVQCILAVGDVISKQMVKFAGNI 137

Query: 67  NSEDVIVVEGI-VNFTPK----AKLGFEIIPEKLEVISKAKTPLPL------------DP 109
             E +I ++   V  + K     +   E+  E++ VIS+AK  LPL            D 
Sbjct: 138 PKESIIDIQAKPVAVSSKIESCTEQSLELSVEQIFVISQAKAQLPLQIEDASRPENADDA 197

Query: 110 TG-KVKAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATA 168
            G  ++   DTRLDNR +DLR P   +IF++ + V R  R+   ++GF EIHTPKII+ A
Sbjct: 198 EGLNIRVNQDTRLDNRVLDLRTPANQAIFRLEAGVCRLFRDILTEQGFTEIHTPKIISAA 257

Query: 169 TEGGTELFPLKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAW 228
           +EGG  +F + YF++ A+LAQSPQLYKQM ++   DKV+ +G +FRAE+ NT RHL E  
Sbjct: 258 SEGGANVFTVSYFKDSAYLAQSPQLYKQMAIAADFDKVYTVGAVFRAEDSNTHRHLTEFV 317

Query: 229 SIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKEL-------KILEFELNEPKKPFP 281
            +D EMAF     EV+  +      +   +R+   KE+       K+  F+  EP     
Sbjct: 318 GLDLEMAFKYHYHEVLHTIGNTFTSIFKGLRDKYAKEIESVGQQYKVDAFKFLEPPL--- 374

Query: 282 RITYDEALEILSDLGKEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIM 341
            + + + + +L + G E    ED+ T  EKLLG+ +      + Y + ++P   +PFY M
Sbjct: 375 ILQFADGVAMLREAGVETGDEEDLSTPNEKLLGRLVKAKYDTDFYILDKFPLAIRPFYTM 434

Query: 342 KYEDKPEVCKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMP 401
              + P    ++D+  RG EI SG QR H  + L+E+ +  G++      Y+ +F YG P
Sbjct: 435 PDPNNPVYSNSYDMFMRGEEILSGAQRIHDPEYLIERAKHHGIDTSKIAAYIESFRYGCP 494

Query: 402 PHGGFGLGAERLIMRMLDIGNIREVILFPRDRRRLVP 438
           PH G G+G ER++M  L + NIR+  +FPRD +RL P
Sbjct: 495 PHAGGGIGMERVVMLYLGLDNIRKTSMFPRDPKRLTP 531


>gb|AAD21582.1| (AF113612) aspartyl tRNA synthetase [Drosophila melanogaster]
           Length = 531
           
 Score =  263 bits (665), Expect = 3e-69
 Identities = 156/457 (34%), Positives = 244/457 (53%), Gaps = 29/457 (6%)

Query: 8   SEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQ-VTAPKKKVPQEIFKLIPKL 66
           SE++ ++    V V G V   +  G   F+ +R +   VQ + A    + +++ K    +
Sbjct: 78  SELSGQVGKGLVWVRGRVHTSRAKGKQCFLILRQQSSTVQCILAVGDVISKQMVKFAGNI 137

Query: 67  NSEDVIVVEGI-VNFTPK----AKLGFEIIPEKLEVISKAKTPLPL------------DP 109
             E +I ++   V  + K     +   E+  E++ VIS+AK  LPL            D 
Sbjct: 138 PKESIIDIQAKPVAVSSKIESCTEQSLELSVEQIFVISQAKAQLPLQIEDASRPENADDA 197

Query: 110 TG-KVKAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATA 168
            G  ++   DTRLDNR +DLR P   +IF++ + V R  R+   ++GF EIHTPKII+ A
Sbjct: 198 EGLNIRVNQDTRLDNRVLDLRTPANQAIFRLEAGVCRLFRDILTEQGFTEIHTPKIISAA 257

Query: 169 TEGGTELFPLKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAW 228
           +EGG  +F + YF++ A+LAQSPQLYKQM ++   DKV+ +G +FRAE+ NT RHL E  
Sbjct: 258 SEGGANVFTVSYFKDSAYLAQSPQLYKQMAIAADFDKVYTVGAVFRAEDSNTHRHLTEFV 317

Query: 229 SIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKEL-------KILEFELNEPKKPFP 281
            +D EMAF     EV+  +      +   +R+   KE+       K+  F+  EP     
Sbjct: 318 GLDLEMAFKYHYHEVLHTIGNTFTSIFKGLRDKYAKEIESVGQQYKVDAFKFLEPPL--- 374

Query: 282 RITYDEALEILSDLGKEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIM 341
            + + + + +L + G E    ED+ T  EKLLG+ +      + Y + ++P   +PFY M
Sbjct: 375 ILQFADGVAMLREAGVETGDEEDLSTPNEKLLGRLVKAKYDTDFYILDKFPLAIRPFYTM 434

Query: 342 KYEDKPEVCKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMP 401
              + P    ++D+  RG EI SG QR H  + L+E+ +  G++      Y+ +F YG P
Sbjct: 435 PDPNNPVYSNSYDMFMRGEEILSGAQRIHDPEYLIERAKHHGIDTSKIAAYIESFRYGCP 494

Query: 402 PHGGFGLGAERLIMRMLDIGNIREVILFPRDRRRLVP 438
           PH G G+G ER++M  L + NIR+  + PRD +RL P
Sbjct: 495 PHAGGGIGMERVVMLYLGLDNIRKTSMLPRDPKRLTP 531


>sp|Q03577|SYD_CAEEL PROBABLE ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
           >gi|280519|pir||S28278 aspartate--tRNA ligase (EC
           6.1.1.12) [similarity] - Caenorhabditis elegans
           >gi|3873792|emb|CAA79536.1| (Z19152) putative
           Aspartyl-tRNA synthetase, contains similarity to Pfam
           domain: PF00152 (tRNA synthetases class II (D, K and
           N)), Score=579.2, E-value=8.2e-171, N=1; PF01336
           (Aspartyl-tRNA synthetase (AspRS), N terminus),
           Score=345.6, E-value=1.7e-100,>
           Length = 531
           
 Score =  259 bits (654), Expect = 6e-68
 Identities = 153/452 (33%), Positives = 240/452 (52%), Gaps = 32/452 (7%)

Query: 17  KKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTA-PKKKVPQEIFKLIPKLNSEDVIVVE 75
           K V V G +   +  G   F+ +R     VQV     +K+ +++ K +  ++ E ++ V 
Sbjct: 82  KDVWVRGRIHTTRSKGKNCFLVLRQGVYTVQVAMFMNEKISKQMLKFVSSISKESIVDVY 141

Query: 76  GIVNFTPK-----AKLGFEIIPEKLEVISKAKTPLPLD--------PTGKVKAE------ 116
             +N          +   E++ +++ V+S +   LPL         PT + KA       
Sbjct: 142 ATINKVDNPIESCTQKDVELLAQQVFVVSTSAPKLPLQIEDASRRAPTDEEKASEQENQL 201

Query: 117 ----LDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGG 172
               LDTRLDNR +DLR P   +IF+I++ +    R      GF+EI  PKII+  +EGG
Sbjct: 202 AVVNLDTRLDNRVIDLRTPTSHAIFRIQAGICNQFRNILDVRGFVEIMAPKIISAPSEGG 261

Query: 173 TELFPLKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDA 232
             +F + YF+  A+LAQSPQLYKQM ++   +KV+ IGP+FRAE+ NT RH+ E   +D 
Sbjct: 262 ANVFEVSYFKGSAYLAQSPQLYKQMAIAGDFEKVYTIGPVFRAEDSNTHRHMTEFVGLDL 321

Query: 233 EMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFP------RITYD 286
           EMAF     EVM+ +  ++  +   +++N + E+  +  +   P +PF        + Y 
Sbjct: 322 EMAFNFHYHEVMETIAEVLTQMFKGLQQNYQDEIAAVGNQY--PAEPFQFCEPPLILKYP 379

Query: 287 EALEILSDLGKEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDK 346
           +A+ +L + G EI   +D+ T  EK LGK + E    + Y + ++P   +PFY M     
Sbjct: 380 DAITLLRENGIEIGDEDDLSTPVEKFLGKLVKEKYSTDFYVLDKFPLSVRPFYTMPDAHD 439

Query: 347 PEVCKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGF 406
                ++D+  RG EI SG QR H  D+LVE+ +   ++    + Y+ +F+YG PPH G 
Sbjct: 440 ERYSNSYDMFMRGEEILSGAQRIHDADMLVERAKHHQVDLAKIQSYIDSFKYGCPPHAGG 499

Query: 407 GLGAERLIMRMLDIGNIREVILFPRDRRRLVP 438
           G+G ER+ M  L + NIR   LFPRD +RL P
Sbjct: 500 GIGLERVTMLFLGLHNIRLASLFPRDPKRLTP 531


>pir||S71074 asparagine--tRNA ligase (EC 6.1.1.22) asnS2 - Lactobacillus
           delbrueckii subsp. bulgaricus
           >gi|1495654|emb|CAA61604.1| (X89439) asparagine--tRNA
           ligase [Lactobacillus delbrueckii]
           Length = 432
           
 Score =  254 bits (641), Expect = 2e-66
 Identities = 149/428 (34%), Positives = 237/428 (54%), Gaps = 17/428 (3%)

Query: 17  KKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVEG 76
           ++V++  W+ + +  G I F+ +RD     Q    K  V +E+F+    L  E    + G
Sbjct: 16  EEVRMHVWLTDKRSSGKIVFLQLRDGTAFFQGVVRKNDVSEEVFEAAKGLRQEASFYLTG 75

Query: 77  IVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPRVMSI 136
            ++   ++  G+EI    LEV+S  +      P    +  +D  LD+R + LR+ R  +I
Sbjct: 76  TIHEDARSHFGYEIQISDLEVVSNNEGY----PITNKEHGIDFLLDHRHLWLRSRRPFAI 131

Query: 137 FKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFLAQSPQLYKQ 196
            +IR+ +F+AT +FF  EGF++   P ++ +A EG TELF + YF +DA+L+QS QLY +
Sbjct: 132 MQIRNRIFKATVDFFENEGFVKFDAPLLMHSAPEGTTELFHIDYFNHDAYLSQSGQLYGE 191

Query: 197 MMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYVIN 256
            + +    K+F  GP FRAE   T RHL E W ++ EMA++  ++E +DL ER + YV+ 
Sbjct: 192 -VGAEAFGKIFTFGPTFRAEASKTRRHLTEFWMMEPEMAWMH-QDESLDLQERFLSYVVG 249

Query: 257 YVRENNEKELKILEFELNEPKKP----FPRITYDEALEILSDLGKEIPWGEDIDTEGEKL 312
            V E+ E EL IL  +L++ +      + R++YD+A+++L + GK+  WG+D     E  
Sbjct: 250 QVLEHCEYELSILGRDLDKLRPAAEGNYTRLSYDDAVKMLQEAGKDFKWGDDFGAPDEAF 309

Query: 313 LGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEY-RGV-EISSGGQREH 370
           L +     +    +FI  YP   KPFY+ K  + P      D+E   G  EI  G +RE 
Sbjct: 310 LSE-----QFDRPFFIVNYPVAIKPFYMKKNPENPLTYLCADVEAPEGYGEIMGGSEREA 364

Query: 371 RHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFP 430
            +D L  QI E GLN + + +YL   +YG  PH GFG+G ER+I  +  + ++RE + FP
Sbjct: 365 DYDTLKAQIEEAGLNLDDYSWYLDLRKYGSVPHSGFGMGFERVIAWICKLDHVREAVPFP 424

Query: 431 RDRRRLVP 438
           R   R+ P
Sbjct: 425 RMINRMQP 432


>pir||S71072 asparagine--tRNA ligase (EC 6.1.1.22) asnS1 - Lactobacillus
           delbrueckii subsp. bulgaricus
           Length = 432
           
 Score =  252 bits (638), Expect = 4e-66
 Identities = 148/428 (34%), Positives = 237/428 (54%), Gaps = 17/428 (3%)

Query: 17  KKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVEG 76
           ++V++  W+ + +  G I F+ +RD     Q    K  V +E+F+    L  E    + G
Sbjct: 16  EEVRMHVWLADKRSSGKIVFLQLRDGTAFFQGVVRKNDVSEEVFEAAKGLRQEASFYLTG 75

Query: 77  IVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPRVMSI 136
            ++   ++  G+EI    LEV+S  +      P    +  +D  LD+R + LR+ R  +I
Sbjct: 76  TIHEDARSHFGYEIQISDLEVVSNNEGY----PITNKEHGIDFLLDHRHLWLRSRRPFAI 131

Query: 137 FKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFLAQSPQLYKQ 196
            +IR+ +F+AT +FF  EGF++   P ++ +A EG TELF + YF +DA+L+QS QLY +
Sbjct: 132 MQIRNRIFKATVDFFENEGFVKFDAPLLMHSAPEGTTELFHIDYFNHDAYLSQSGQLYGE 191

Query: 197 MMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYVIN 256
            + +    K+F  GP FRAE   T RHL E W ++ EMA++  ++E +DL ER + YV+ 
Sbjct: 192 -VGAEAFGKIFTFGPTFRAEASKTRRHLTEFWMMEPEMAWMH-QDESLDLQERFLSYVVG 249

Query: 257 YVRENNEKELKILEFELNEPKKP----FPRITYDEALEILSDLGKEIPWGEDIDTEGEKL 312
            V E+ E EL IL  ++++ +      + R++YD+A+++L + GK+  WG+D     E  
Sbjct: 250 QVLEHCEYELSILGRDVDKLRPAAEGNYTRLSYDDAVKMLQEAGKDFKWGDDFGAPDEAF 309

Query: 313 LGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEY-RGV-EISSGGQREH 370
           L +     +    +FI  YP   KPFY+ K  + P      D+E   G  EI  G +RE 
Sbjct: 310 LSE-----QFDRPFFIVNYPVAIKPFYMKKNPENPLTYLCADVEAPEGYGEIMGGSEREA 364

Query: 371 RHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFP 430
            +D L  QI E GLN + + +YL   +YG  PH GFG+G ER+I  +  + ++RE + FP
Sbjct: 365 DYDTLKAQIEEAGLNLDDYSWYLDLRKYGSVPHSGFGMGFERVIAWICKLDHVREAVPFP 424

Query: 431 RDRRRLVP 438
           R   R+ P
Sbjct: 425 RMINRMQP 432


>sp|P54262|SYN_LACDE ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRNA LIGASE) (ASNRS)
           >gi|2145612|pir||S73326 asparagine--tRNA ligase (EC
           6.1.1.22) asnS1 - Lactobacillus delbrueckii
           >gi|1321875|emb|CAA61603.1| (X89438) asparagine--tRNA
           ligase [Lactobacillus delbrueckii]
           Length = 432
           
 Score =  252 bits (638), Expect = 4e-66
 Identities = 148/428 (34%), Positives = 237/428 (54%), Gaps = 17/428 (3%)

Query: 17  KKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVEG 76
           ++V++  W+ + +  G I F+ +RD     Q    K  V +E+F+    L  E    + G
Sbjct: 16  EEVRMHVWLTDKRSSGKIVFLQLRDGTAFFQGVVRKNDVSEEVFEAAKGLRQEASFYLTG 75

Query: 77  IVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPRVMSI 136
            ++   ++  G+EI    LEV+S  +      P    +  +D  LD+R + LR+ R  +I
Sbjct: 76  TIHEDARSHFGYEIQISDLEVVSNNEGY----PITNKEHGIDFLLDHRHLWLRSRRPFAI 131

Query: 137 FKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFLAQSPQLYKQ 196
            +IR+ +F+AT +FF  EGF++   P ++ +A EG TELF + YF +DA+L+QS QLY +
Sbjct: 132 MQIRNRIFKATVDFFENEGFVKFDAPLLMHSAPEGTTELFHIDYFNHDAYLSQSGQLYGE 191

Query: 197 MMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYVIN 256
            + +    K+F  GP FRAE   T RHL E W ++ EMA++  ++E +DL ER + YV+ 
Sbjct: 192 -VGAEAFGKIFTFGPTFRAEASKTRRHLTEFWMMEPEMAWMH-QDESLDLQERFLSYVVG 249

Query: 257 YVRENNEKELKILEFELNEPKKP----FPRITYDEALEILSDLGKEIPWGEDIDTEGEKL 312
            V E+ E EL IL  ++++ +      + R++YD+A+++L + GK+  WG+D     E  
Sbjct: 250 QVLEHCEYELSILGRDVDKLRPAAEGNYTRLSYDDAVKMLQEAGKDFKWGDDFGAPDEAF 309

Query: 313 LGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEY-RGV-EISSGGQREH 370
           L +     +    +FI  YP   KPFY+ K  + P      D+E   G  EI  G +RE 
Sbjct: 310 LSE-----QFDRPFFIVNYPVAIKPFYMKKNPENPLTYLCADVEAPEGYGEIMGGSEREA 364

Query: 371 RHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFP 430
            +D L  QI E GLN + + +YL   +YG  PH GFG+G ER+I  +  + ++RE + FP
Sbjct: 365 DYDTLKAQIEEAGLNLDDYSWYLDLRKYGSVPHSGFGMGFERVIAWICKLDHVREAVPFP 424

Query: 431 RDRRRLVP 438
           R   R+ P
Sbjct: 425 RMINRMQP 432


>dbj|BAB05415.1| (AP001512) asparaginyl-tRNA synthetase [Bacillus halodurans]
           Length = 430
           
 Score =  250 bits (631), Expect = 3e-65
 Identities = 150/429 (34%), Positives = 237/429 (54%), Gaps = 19/429 (4%)

Query: 17  KKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVEG 76
           ++V +  W+   +  G I F+ +RD  G +Q    K +V  E F+    L  E  + V G
Sbjct: 14  QEVTLGAWLANKRSSGKIAFLQLRDGTGFIQGVVVKAEVGDEWFQKAKNLTQESSLYVTG 73

Query: 77  IVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPRVMSI 136
           IV    +A  G+E+     ++I +A T  P+ P    +   +  +D+R + +R+ +  ++
Sbjct: 74  IVRKDERAPSGYELTVTSFDIIHEA-TDYPITPK---EHGTEFLMDHRHLWIRSRKQHAV 129

Query: 137 FKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFLAQSPQLYKQ 196
            +IR+ + RAT EFF++ GF+++  P +  +A EG TELF  KYF+ DAFL+QS QLY +
Sbjct: 130 LRIRNEIIRATYEFFHENGFVKVDPPILTGSAPEGTTELFHTKYFDEDAFLSQSGQLYME 189

Query: 197 MMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYVIN 256
              +    +VF  GP FRAE+  T RHL E W I+ EMAF+E EE  +++ E  + Y++ 
Sbjct: 190 -AAALAFGRVFSFGPTFRAEKSKTRRHLIEFWMIEPEMAFVEFEES-LEIQENYVAYIVQ 247

Query: 257 YVRENNEKELKILEFE---LNEPKKPFPRITYDEALEILSDLG-KEIPWGEDIDTEGEKL 312
            V ++   ELK L  +   L   + PFPRI+YD+A++ L + G  +I WG+D     E  
Sbjct: 248 SVLKHCAIELKTLGRDTSVLESIQAPFPRISYDDAIKFLHEKGFDDIEWGDDFGAPHETA 307

Query: 313 LGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDL---EYRGVEISSGGQRE 369
           + ++       +  FI  YP+  KPFY+    ++ +V    DL   E  G EI  G QR 
Sbjct: 308 IAEHF-----DKPVFITHYPTSLKPFYMEPDPNRDDVVLCADLIAPEGYG-EIIGGSQRI 361

Query: 370 HRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILF 429
             +D+L +++ E  L+ +++ +YL   +YG  PH GFGLG ER +  +   G++RE I F
Sbjct: 362 SDYDLLKKRLEEHDLSLDAYAWYLDLRKYGSVPHSGFGLGLERTVGWISGAGHVRETIPF 421

Query: 430 PRDRRRLVP 438
           PR   RL P
Sbjct: 422 PRLLNRLYP 430


>sp|P54263|SYN_THETH ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRNA LIGASE) (ASNRS)
           >gi|1004327|emb|CAA62491.1| (X91009) asparaginyl-tRNA
           synthetase [Thermus thermophilus]
           Length = 438
           
 Score =  228 bits (575), Expect = 1e-58
 Identities = 147/436 (33%), Positives = 236/436 (53%), Gaps = 25/436 (5%)

Query: 17  KKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVEG 76
           ++V++ GW+ + +  G I F+ +RD  G +Q T  + +VP+ +F+    L  E  + V G
Sbjct: 14  QEVELRGWLYQRRSKGKIHFLILRDGTGFLQATVVQGEVPEAVFREADHLPQETALRVWG 73

Query: 77  IVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPRVMSI 136
            V    +A  GFE+    L+V+S+ +   P+ P    +  +D  +D+R + LR+ R  ++
Sbjct: 74  RVREDRRAPGGFELAVRDLQVVSRPQGEYPIGPK---EHGIDFLMDHRHLWLRHRRPFAV 130

Query: 137 FKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFEND-AFLAQSPQLYK 195
            +IR  + RA  EFF + GF+    P +  +A EG TELF ++ F+ + A+L+QS QLY 
Sbjct: 131 MRIRDELERAIHEFFGERGFLRFDAPILTPSAVEGTTELFEVELFDGEKAYLSQSGQLYA 190

Query: 196 QMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYVI 255
           +   +    KV+  GP FRAE   T RHL E W ++ E+AF+  EE  M L E L+ +++
Sbjct: 191 EAG-ALAFAKVYTFGPTFRAERSKTRRHLLEFWMVEPEVAFMTHEEN-MALQEELVSFLV 248

Query: 256 NYVRENNEKELKIL--EFELNEPKKP--FPRITYDEALEILSDLGKE------IPWGEDI 305
             V E   +EL++L  + +  EP     +PR+TY EA+ +++ + +E      +P+GED 
Sbjct: 249 ARVLERRSRELEMLGRDPKALEPAAEGHYPRLTYKEAVALVNRIAQEDPEVPPLPYGEDF 308

Query: 306 DTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDL---EYRGVEI 362
               E  L +           F+ RYP+  K FY+    + PE+    DL   E  G EI
Sbjct: 309 GAPHEAALSRRF-----DRPVFVERYPARIKAFYMEPDPEDPELVLNDDLLRPEGYG-EI 362

Query: 363 SSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGN 422
             G QR H  ++L  +I+E GL  E +++YL    +G  PH GFGLG ER +  +  + +
Sbjct: 363 IGGSQRIHDLELLRRKIQEFGLPEEVYDWYLDLRRFGSVPHSGFGLGLERTVAWICGLAH 422

Query: 423 IREVILFPRDRRRLVP 438
           +RE I FPR   R+ P
Sbjct: 423 VREAIPFPRMYTRMRP 438


>sp|Q19722|SYN_CAEEL PROBABLE ASPARAGINYL-TRNA SYNTHETASE, CYTOPLASMIC (ASPARAGINE--TRNA
           LIGASE) (ASNRS) >gi|7499656|pir||T21253 hypothetical
           protein F22D6.3 - Caenorhabditis elegans
           >gi|3876241|emb|CAA95808.1| (Z71262) predicted using
           Genefinder~Similarity to Brugia asparaginyl-tRNA
           synthetase (SW:63KD_BRUMA), contains similarity to Pfam
           domain: PF00152 (tRNA synthetases class II (D, K and
           N)), Score=452.1, E-value=1.6e-132, N=1~cDNA EST
           EMBL:Z14941 comes fr>
           Length = 545
           
 Score =  196 bits (493), Expect = 4e-49
 Identities = 134/435 (30%), Positives = 225/435 (50%), Gaps = 24/435 (5%)

Query: 17  KKVKVAGWVQEVKDLG-GIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVE 75
           ++V +  WV  ++  G  + F+ +RD  G +Q     K    + +  +  L++E  + V 
Sbjct: 122 QRVSIKAWVHRLRRQGKSLMFLVLRDGYGFLQCVLNDKLC--QSYDAVT-LSTETSVQVY 178

Query: 76  GIVNFTPKAKL---GFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPR 132
           GI+   P  K    G E+  +  EVI KA     +D      A +D  LDNR + +R   
Sbjct: 179 GIIKALPDGKSAPDGHELTVDYWEVIGKAPAG-GIDNVLNESAGVDVMLDNRHLVIRGEN 237

Query: 133 VMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFLAQSPQ 192
              I +IR++  RA R+ F+  G+ E+  P ++ T  EGG+ LF L Y+   A+L QS Q
Sbjct: 238 ASRILRIRAAATRAMRDHFFAAGYTEVAPPTLVQTQVEGGSTLFGLDYYGEPAYLTQSSQ 297

Query: 193 LYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLIL 252
           LY +   +  L  V+ I   +RAE+  T RHL+E   ++AE AFI + +++MD +E L+ 
Sbjct: 298 LYLE-TCNAALGDVYCISQSYRAEKSRTRRHLSEYQHVEAECAFI-TFDQLMDRIEALVC 355

Query: 253 YVINYVREN--NEKELKILEFELNEPKKPFPRITYDEALE------ILSDLGKEIPWGED 304
             ++ +  +   +  ++ +      P +PF R+ Y EA+E      + +++G++  +GED
Sbjct: 356 DTVDRLLADPVTKSLIEFVNPGYKAPARPFKRMPYKEAIEWLQKNDVRNEMGEKFVYGED 415

Query: 305 IDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGV-EIS 363
           I    E    + M +  G  +  + R+P   K FY+ +  D  E+ ++ DL   GV EI 
Sbjct: 416 IAEAAE----RRMTDTIGVPI-LLNRFPHGIKAFYMPRCADDNELTESVDLLMPGVGEIV 470

Query: 364 SGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNI 423
            G  R  + D L+    + GL+ +++ +Y+   +YG  PHGG+GLG ER I  + D  +I
Sbjct: 471 GGSMRIWKEDQLLAAFEKGGLDSKNYYWYMDQRKYGSVPHGGYGLGLERFICWLTDTNHI 530

Query: 424 REVILFPRDRRRLVP 438
           R+V L+PR   R  P
Sbjct: 531 RDVCLYPRFVGRCAP 545


>gb|AAD55420.1|AF181634_1 (AF181634) BcDNA.GH06451 [Drosophila melanogaster]
           >gi|7298549|gb|AAF53768.1| (AE003661) BcDNA:GH06451 gene
           product [Drosophila melanogaster]
           Length = 558
           
 Score =  192 bits (482), Expect = 8e-48
 Identities = 137/433 (31%), Positives = 227/433 (51%), Gaps = 23/433 (5%)

Query: 18  KVKVAGWVQEVKDLG-GIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVEG 76
           +VKV GWV  ++  G  + FI +RD  G +Q      ++ Q    L   L++E  +V+ G
Sbjct: 137 RVKVYGWVHRLRRQGKSLIFITLRDGTGFLQCVL-NDQLCQTYDALT--LSTESSVVLFG 193

Query: 77  IVNFTPKAKL---GFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPRV 133
            +   P+ K    G E+  +  E+I  A  P   D     +A+ D +LDNR + +R    
Sbjct: 194 TLKLVPEGKTAPGGHELNVDYWELIGLAP-PGGADAILNEEAQPDVQLDNRHIMIRGENT 252

Query: 134 MSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFLAQSPQL 193
             + K+RS V +A R  +   G+ E+  P ++ T  EGG+ LF LKYF  +A+L QS QL
Sbjct: 253 SKVLKMRSVVTQAFRGHYEARGYNEVTPPTLVQTQVEGGSTLFKLKYFGEEAYLTQSSQL 312

Query: 194 YKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILY 253
           Y +  +   L  VF I   +RAE+  T RHL E   ++AE  F+ + ++++D LE L+  
Sbjct: 313 YLETCL-PALGDVFTISQSYRAEQSRTRRHLAEYTHVEAECPFL-TFDDLLDRLEDLVCD 370

Query: 254 VINYVRENNEKEL-KILEFELNEPKKPFPRITYDEALE------ILSDLGKEIPWGEDID 306
           V++ V ++    L K L  +   P+KPF R+ Y++A++      +  D G    +GEDI 
Sbjct: 371 VVDRVLKSPWGYLVKELNPDFKPPQKPFRRMNYEDAIKWLKENNVTKDDGTFYEFGEDIP 430

Query: 307 TEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGV-EISSG 365
              E+      + +   E   + R+P+E K FY+ + ++   + ++ D+    V EI  G
Sbjct: 431 EAPER-----KMTDTINEPIMLCRFPAEIKSFYMQRCKEDQRLTESVDVLLPNVGEIVGG 485

Query: 366 GQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIRE 425
             R +  + L++  + +G++P+ + +Y     YG  PHGG+GLG ER +  +L+  +IRE
Sbjct: 486 SMRIYDSEELLKGYKREGIDPQPYYWYTDQRVYGTMPHGGYGLGLERFLCWLLNRYHIRE 545

Query: 426 VILFPRDRRRLVP 438
           V L+PR   R  P
Sbjct: 546 VCLYPRFLDRCRP 558


>gi|4758762 asparaginyl-tRNA synthetase [Homo sapiens]
           >gi|3915059|sp|O43776|SYN_HUMAN ASPARAGINYL-TRNA
           SYNTHETASE, CYTOPLASMIC (ASPARAGINE--TRNA LIGASE)
           (ASNRS) >gi|2764505|emb|CAA04008.1| (AJ000334)
           asparaginyl-tRNA synthetase [Homo sapiens]
           >gi|3894218|dbj|BAA34600.1| (D84273) Asparaginyl tRNA
           Synthetase [Homo sapiens]
           Length = 548
           
 Score =  191 bits (481), Expect = 1e-47
 Identities = 134/439 (30%), Positives = 224/439 (50%), Gaps = 23/439 (5%)

Query: 12  EELNGKKVKVAGWVQEVKDLG-GIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSED 70
           E   G++VKV GWV  ++  G  + F+ +RD  G +Q     +        L   L++E 
Sbjct: 121 EGYRGQRVKVFGWVHRLRRQGKNLMFLVLRDGTGYLQCVLADELCQCYNGVL---LSTES 177

Query: 71  VIVVEGIVNFTPKAKL---GFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMD 127
            + V G++N TPK K    G E+  +  E+I  A      D     ++++D +L+NR M 
Sbjct: 178 SVAVYGMLNLTPKGKQAPGGHELSCDFWELIGLAPAG-GADNLINEESDVDVQLNNRHMM 236

Query: 128 LRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFL 187
           +R   +  I K RS V R  R+ F+  G+ E+  P ++ T  EGG  LF L YF  +AFL
Sbjct: 237 IRGENMSKILKARSMVTRCFRDHFFDRGYYEVTPPTLVQTQVEGGATLFKLDYFGEEAFL 296

Query: 188 AQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLL 247
            QS QLY +  +   L  VF I   +RAE+  T RHL E   ++AE  F+ + +++++ L
Sbjct: 297 TQSSQLYLETCL-PALGDVFCIAQSYRAEQSRTRRHLAEYTHVEAECPFL-TFDDLLNRL 354

Query: 248 ERLILYVINYVRENNEKEL-KILEFELNEPKKPFPRITYDEAL------EILSDLGKEIP 300
           E L+  V++ + ++    +   L      PK+PF R+ Y +A+      ++  + G    
Sbjct: 355 EDLVCDVVDRILKSPAGSIVHELNPNFQPPKRPFKRMNYSDAIVWLKEHDVKKEDGTFYE 414

Query: 301 WGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGV 360
           +GEDI    E+L+   +      E   + R+P E K FY+ +  +   + ++ D+    V
Sbjct: 415 FGEDIPEAPERLMTDTI-----NEPILLCRFPVEIKSFYMQRCPEDSRLTESVDVLMPNV 469

Query: 361 -EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLD 419
            EI  G  R    + ++   + +G++P  + +Y    +YG  PHGG+GLG ER +  +L+
Sbjct: 470 GEIVGGSMRIFDSEEILAGYKREGIDPTPYYWYTDQRKYGTCPHGGYGLGLERFLTWILN 529

Query: 420 IGNIREVILFPRDRRRLVP 438
             +IR+V L+PR  +R  P
Sbjct: 530 RYHIRDVCLYPRFVQRCTP 548


>gi|11426051 asparaginyl-tRNA synthetase [Homo sapiens]
           Length = 572
           
 Score =  191 bits (481), Expect = 1e-47
 Identities = 134/439 (30%), Positives = 224/439 (50%), Gaps = 23/439 (5%)

Query: 12  EELNGKKVKVAGWVQEVKDLG-GIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSED 70
           E   G++VKV GWV  ++  G  + F+ +RD  G +Q     +        L   L++E 
Sbjct: 145 EGYRGQRVKVFGWVHRLRRQGKNLMFLVLRDGTGYLQCVLADELCQCYNGVL---LSTES 201

Query: 71  VIVVEGIVNFTPKAKL---GFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMD 127
            + V G++N TPK K    G E+  +  E+I  A      D     ++++D +L+NR M 
Sbjct: 202 SVAVYGMLNLTPKGKQAPGGHELSCDFWELIGLAPAG-GADNLINEESDVDVQLNNRHMM 260

Query: 128 LRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFL 187
           +R   +  I K RS V R  R+ F+  G+ E+  P ++ T  EGG  LF L YF  +AFL
Sbjct: 261 IRGENMSKILKARSMVTRCFRDHFFDRGYYEVTPPTLVQTQVEGGATLFKLDYFGEEAFL 320

Query: 188 AQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLL 247
            QS QLY +  +   L  VF I   +RAE+  T RHL E   ++AE  F+ + +++++ L
Sbjct: 321 TQSSQLYLETCL-PALGDVFCIAQSYRAEQSRTRRHLAEYTHVEAECPFL-TFDDLLNRL 378

Query: 248 ERLILYVINYVRENNEKEL-KILEFELNEPKKPFPRITYDEAL------EILSDLGKEIP 300
           E L+  V++ + ++    +   L      PK+PF R+ Y +A+      ++  + G    
Sbjct: 379 EDLVCDVVDRILKSPAGSIVHELNPNFQPPKRPFKRMNYSDAIVWLKEHDVKKEDGTFYE 438

Query: 301 WGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGV 360
           +GEDI    E+L+   +      E   + R+P E K FY+ +  +   + ++ D+    V
Sbjct: 439 FGEDIPEAPERLMTDTI-----NEPILLCRFPVEIKSFYMQRCPEDSRLTESVDVLMPNV 493

Query: 361 -EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLD 419
            EI  G  R    + ++   + +G++P  + +Y    +YG  PHGG+GLG ER +  +L+
Sbjct: 494 GEIVGGSMRIFDSEEILAGYKREGIDPTPYYWYTDQRKYGTCPHGGYGLGLERFLTWILN 553

Query: 420 IGNIREVILFPRDRRRLVP 438
             +IR+V L+PR  +R  P
Sbjct: 554 RYHIRDVCLYPRFVQRCTP 572


>sp|P75521|SYN_MYCPN ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRNA LIGASE) (ASNRS)
           >gi|2146064|pir||S73906 asparagine--tRNA ligase (EC
           6.1.1.22) asnS - Mycoplasma pneumoniae (strain ATCC
           29342) >gi|1674281|gb|AAB96228.1| (AE000057)
           asparaginyl-tRNA synthetase [Mycoplasma pneumoniae]
           Length = 455
           
 Score =  190 bits (479), Expect = 2e-47
 Identities = 129/443 (29%), Positives = 222/443 (49%), Gaps = 33/443 (7%)

Query: 13  ELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVI 72
           +   KK+K+ GW++  +    I F+ + D   ++ + A  K+   E+F L   ++    +
Sbjct: 15  QFKNKKIKLTGWLKNKRTSANIIFLEVNDGSTLLNLQAVVKQDQPELFALAESISLASAV 74

Query: 73  VVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPR 132
            V G V  TPK+K   E++ +++ V+S A+   PL    K +  L+   +N ++ +R   
Sbjct: 75  SVSGTVALTPKSKQPLELVVKQINVLSTARADYPLQ---KKEHSLEFFRNNAYLRVRART 131

Query: 133 VMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLK----YFENDAFLA 188
             +I K+RS + +A  ++F+K  F+ +H+P + +   EG  E F LK    +F    +L 
Sbjct: 132 YFAIMKVRSLLSQAIFDYFFKNDFVLVHSPILTSNDCEGAGETFELKQGKEFFNKTTYLT 191

Query: 189 QSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLE 248
            S Q +     +    KVF  GP FRAE+ +T+RHL+E W I+ E+AF  + ++++ L+E
Sbjct: 192 VSGQ-FGAECYAQAFKKVFTFGPTFRAEKSHTSRHLSEFWMIEPEVAF-ANLKDLIKLIE 249

Query: 249 RLILYVINYVRENNEKELKILEFELN----------EPKKPFPRITYDEALEILSDLG-- 296
             +  VI  V +  ++EL  LE + +             K F  + Y +ALEIL      
Sbjct: 250 STVKTVIKQVMQKAKQELDFLEKQFDVKLMERLKQITSTKNFHVLEYTKALEILKTAQAS 309

Query: 297 -------KEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEV 349
                  ++  +G D+ TE E+ L +    N+     F+  YP + K FY MK       
Sbjct: 310 GQANFEVQDFNFGLDLKTEHERFLCEQHFHNQPV---FVINYPKDFKAFY-MKQNADGRT 365

Query: 350 CKAFDLEYRGV-EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGL 408
             A DL +  + EI  G +RE   + LVE+ +   ++ ++  +YL   ++G     GFGL
Sbjct: 366 VGAVDLLFPQIGEICGGSEREGNLEKLVERCQAMQIDTQTLNWYLDMRKWGYFASAGFGL 425

Query: 409 GAERLIMRMLDIGNIREVILFPR 431
           G +RL+  +  + NIR+ I FPR
Sbjct: 426 GFDRLLAYICGLENIRDAIPFPR 448


>gi|6321807 Asparaginyl-tRNA synthetase; Ded81p [Saccharomyces cerevisiae]
           >gi|731638|sp|P38707|SYNC_YEAST ASPARAGINYL-TRNA
           SYNTHETASE, CYTOPLASMIC (ASPARAGINE--TRNA LIGASE)
           (ASNRS) >gi|626599|pir||S46775 hypothetical protein
           YHR019c - yeast (Saccharomyces cerevisiae)
           >gi|500693|gb|AAB68874.1| (U10399) Ded81p:
           Asparaginyl-tRNA synthetase [Saccharomyces cerevisiae]
           Length = 554
           
 Score =  189 bits (475), Expect = 6e-47
 Identities = 129/439 (29%), Positives = 232/439 (52%), Gaps = 29/439 (6%)

Query: 16  GKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQ-VTAPKKKVPQEIFKLIPKLNSEDVIVV 74
           G++VKV+GW+  ++    + F+ +RD  G +Q V +    + Q+   L      E  + +
Sbjct: 129 GQRVKVSGWIHRLRSNKKVIFVVLRDGSGFIQCVLSGDLALAQQTLDL----TLESTVTL 184

Query: 75  EGIVNFTPKAKL---GFEIIPEKLEVISKAKTPLPLDP-TGKVKAELDTRL--DNRFMDL 128
            G +   P+ K    G E+  +  EV+  A  P   D  T K+    D  L  D R + L
Sbjct: 185 YGTIVKLPEGKTAPGGVELNVDYYEVVGLA--PGGEDSFTNKIAEGSDPSLLLDQRHLAL 242

Query: 129 RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFLA 188
           R   + ++ K+R+++ ++ R  + +E   E+  P ++ T  EGG+ LF + Y+  +A+L 
Sbjct: 243 RGDALSAVMKVRAALLKSVRRVYDEEHLTEVTPPCMVQTQVEGGSTLFKMNYYGEEAYLT 302

Query: 189 QSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLE 248
           QS QLY +  +++ L  V+ I   FRAE+ +T RHL+E   I+AE+AF+ + ++++  +E
Sbjct: 303 QSSQLYLETCLAS-LGDVYTIQESFRAEKSHTRRHLSEYTHIEAELAFL-TFDDLLQHIE 360

Query: 249 RLILYVINYVREN--NEKELKILEFELNEPKKPFPRITYDEAL------EILSDLGKEIP 300
            LI+  + YV E+      +K L      PK PF R+ Y +A+      +I ++ G++  
Sbjct: 361 TLIVKSVQYVLEDPIAGPLVKQLNPNFKAPKAPFMRLQYKDAITWLNEHDIKNEEGEDFK 420

Query: 301 WGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGV 360
           +G+DI    E    + M +  G  + F+ R+P E K FY+ +  D P V ++ D+    V
Sbjct: 421 FGDDIAEAAE----RKMTDTIGVPI-FLTRFPVEIKSFYMKRCSDDPRVTESVDVLMPNV 475

Query: 361 -EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLD 419
            EI+ G  R    D L+   + +G++ +++ +++   +YG  PHGG+G+G ER++  + D
Sbjct: 476 GEITGGSMRIDDMDELMAGFKREGIDTDAYYWFIDQRKYGTCPHGGYGIGTERILAWLCD 535

Query: 420 IGNIREVILFPRDRRRLVP 438
              +R+  L+PR   R  P
Sbjct: 536 RFTVRDCSLYPRFSGRCKP 554


>sp|P47359|SYN_MYCGE ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRNA LIGASE) (ASNRS)
           >gi|1361447|pir||E64212 asparagine--tRNA ligase (EC
           6.1.1.22) - Mycoplasma genitalium
           >gi|3844702|gb|AAC71331.1| (U39691) asparaginyl-tRNA
           synthetase (asnS) [Mycoplasma genitalium]
           Length = 456
           
 Score =  189 bits (474), Expect = 7e-47
 Identities = 135/444 (30%), Positives = 220/444 (49%), Gaps = 34/444 (7%)

Query: 13  ELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGI--VQVTAPKKKVPQEIFKLIPKLNSED 70
           + N K++K++GWV+  +    I F+ I D   I  +Q    ++  PQ +F L+  +N   
Sbjct: 15  KFNNKQIKLSGWVKNKRASANIIFLAISDGSSINTLQAVVKQEDNPQ-VFSLLQTVNLAS 73

Query: 71  VIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRN 130
            ++V G +  TPKAK   E+  +++ ++++A++  PL    K +   +    N  + +R 
Sbjct: 74  AVMVWGEIILTPKAKQPLELKLKQVSLLAQAESDYPLQ---KKEHSQEFFRSNAHLRVRA 130

Query: 131 PRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLK----YFENDAF 186
               ++ KIRS +  A  E+F+K  FI + +P + +   EG  E F +K    +F    F
Sbjct: 131 KTYFAVMKIRSVLSHAIFEYFFKNDFILVQSPILTSNDCEGAGETFVIKDSETFFNKTTF 190

Query: 187 LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDL 246
           L  S Q   +   +    KVF  GP FRAE+ +T RHL+E W I+ E+AF   ++ +M L
Sbjct: 191 LTVSGQFGAEAF-AQAFKKVFTFGPTFRAEKSHTNRHLSEFWMIEPEIAFANLKD-LMQL 248

Query: 247 LERLILYVINYVRENNEKELKILEFELNEP----------KKPFPRITYDEALEIL---S 293
           ++ LI ++I  V EN   EL +L  + +             K FP I Y +AL IL   S
Sbjct: 249 IQNLIKFLIKKVMENASDELNVLAKQFSNDIISNLKTIISTKKFPIIEYSKALAILKESS 308

Query: 294 DLGK------EIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKP 347
           D  K      +  +G D+ TE E+ L +   +N+     F+  YP E K FY+    D  
Sbjct: 309 DTKKTNFELNDFSFGIDLKTEHERFLCEQYFQNQPL---FVINYPKELKAFYMKTNTDNK 365

Query: 348 EVCKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFG 407
            V     L  +  EI  G +RE   + L  + +   ++ +S  +YL   ++G     GFG
Sbjct: 366 TVAAVDLLLPKIGEICGGSERESDLNQLKNRCQSLNIDTKSLNWYLDMRKWGYFASAGFG 425

Query: 408 LGAERLIMRMLDIGNIREVILFPR 431
           LG +RL+  +  + NIR+ I FPR
Sbjct: 426 LGFDRLLAYICGLENIRDAIPFPR 449


>sp|P43829|SYN_HAEIN ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRNA LIGASE) (ASNRS)
           >gi|1073865|pir||B64115 asparagine--tRNA ligase (EC
           6.1.1.22) - Haemophilus influenzae (strain Rd KW20)
           >gi|1574761|gb|AAC22949.1| (U32810) asparaginyl-tRNA
           synthetase (asnS) [Haemophilus influenzae Rd]
           Length = 477
           
 Score =  183 bits (459), Expect = 4e-45
 Identities = 135/459 (29%), Positives = 218/459 (47%), Gaps = 53/459 (11%)

Query: 16  GKKVKVAGWVQEVKDL-GGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVV 74
           G+ V V GWV+  +D   G+ F+ + D      + A      +     I +L +   ++V
Sbjct: 28  GETVTVRGWVRTRRDSKAGLSFLAVYDGSCFDPIQAIINNDIENYESEILRLTTGCSVIV 87

Query: 75  EGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPRVM 134
            G V  +P      E+  EK+EV    + P    P    +  ++   +   +  R   + 
Sbjct: 88  TGKVVESPAEGQAVELQAEKVEVTGFVEDP-DTYPMAAKRHSIEYLREVAHLRPRTNIIG 146

Query: 135 SIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLK--------------- 179
           ++ ++R  + +A   FF+++GF  + TP I A+ TEG  E+F +                
Sbjct: 147 AVARVRHCLSQAIHRFFHEQGFYWVATPLITASDTEGAGEMFRVSTLDLENLPRSENGKV 206

Query: 180 -----YFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEM 234
                +F  ++FL  S QL  +   +  L K++  GP FRAE  NTTRHL E W ++ E+
Sbjct: 207 DFSQDFFGKESFLTVSGQLNGETY-ACALSKIYTFGPTFRAENSNTTRHLAEFWMVEPEV 265

Query: 235 AFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEP---------KKPFPRITY 285
           AF    +    L E ++ YV   V    + +L+  E  +++             F +I Y
Sbjct: 266 AFATLADNAK-LAEDMLKYVFRAVLAERKDDLQFFEKHVDKDVITRLENFVNSDFAQIDY 324

Query: 286 DEALEILSDLGKE----IPWGEDIDTEGEKLLGKYMLENEGAELYF-----IYRYPSEAK 336
            +A+++L   GK+    + WG D+ +E E+ L         AE YF     +  YP + K
Sbjct: 325 TDAIDVLLKSGKKFEFPVSWGIDLSSEHERFL---------AEEYFKSPVVVKNYPKDIK 375

Query: 337 PFYIMKYEDKPEVCKAFDLEYRGV-EISSGGQREHRHDILVEQIREKGLNPESFEFYLRA 395
            FY M+  D  +   A D+   G+ EI  G QRE R ++L +++ E GLNP+ + +Y   
Sbjct: 376 AFY-MRLNDDEKTVAAMDVLAPGIGEIIGGSQREERLEVLDKRMEEMGLNPDDYWWYRDL 434

Query: 396 FEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRR 434
            +YG  PH GFGLG ERLI+ +  + NIR+VI FPR  R
Sbjct: 435 RKYGSVPHSGFGLGFERLIVYVTGVQNIRDVIPFPRAPR 473


>pir||A82901 asparaginyl-tRNA synthetase UU365 [imported] - Ureaplasma
           urealyticum >gi|6899346|gb|AAF30774.1|AE002133_7
           (AE002133) asparaginyl-tRNA synthetase [Ureaplasma
           urealyticum]
           Length = 454
           
 Score =  181 bits (455), Expect = 1e-44
 Identities = 126/447 (28%), Positives = 216/447 (48%), Gaps = 32/447 (7%)

Query: 13  ELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVI 72
           +L G+K+++  WV+  +D   I F+ + D   +  + A  +    + ++ I        +
Sbjct: 15  KLEGQKIQIKAWVRSNRDSKKIGFLVLNDGSSLTNLQAVYRVDKIDNYEEIAAARMWAAV 74

Query: 73  VVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPR 132
           V+EG++  TP AK   E+     +++ ++     L         L+T   N  +  R   
Sbjct: 75  VIEGVIKLTPTAKQPLELEVLNAQILKQSDEDFLLSNND---LNLETLRLNAHLRPRTNL 131

Query: 133 VMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFLAQSPQ 192
             +I K+R+++  A  EF  +  +  +  P       EG  E F ++ F+N+ F  +   
Sbjct: 132 FHAIMKVRATLAFAVHEFMNQNEYSWLAAPLFTGNDAEGAGETFSIQKFDNEEFFGKQTH 191

Query: 193 L-----YKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLL 247
           L      +    +     V+  GP FRAE+ +T RHL E W I+ EMAF++ +  + D++
Sbjct: 192 LSVTGQLQAEAYAQAFGNVYTFGPTFRAEKSHTNRHLAEFWMIEPEMAFVDLKG-MQDIV 250

Query: 248 ERLILYVINYVRENNEKELKILEFELNEP---------KKPFPRITYDEALEILSDLGK- 297
           E L+ +VI  V E N++EL+ L    +E          +  F RI Y +A++IL+D  K 
Sbjct: 251 EDLVKHVIKAVLEKNQQELEFLAQRNDENLIKKLQKVVESKFERIEYKDAVKILADAVKN 310

Query: 298 -------EIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVC 350
                  EI +G D+ +E E+    YM E       F+  YP + K FY MK  D  +  
Sbjct: 311 GHQFENNEIFFGMDLGSEHER----YMCETYHQGPVFLQNYPKDIKAFY-MKLNDDQQTV 365

Query: 351 KAFDLEYRGV-EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLG 409
            + DL   GV E+  G QRE  ++ L+++ +E  +  ES ++YL    +G     GFG+G
Sbjct: 366 ASTDLLIPGVGELVGGSQREDSYEKLLKRCQELKMPIESLQWYLDLRRFGYYMSSGFGIG 425

Query: 410 AERLIMRMLDIGNIREVILFPRDRRRL 436
            ERL+M +  + NI++ I FPR   ++
Sbjct: 426 FERLVMYVTGVNNIKDTIPFPRSHGQI 452


>sp|P10723|SYN_BRUMA ASPARAGINYL-TRNA SYNTHETASE, CYTOPLASMIC (ASPARAGINE--TRNA LIGASE)
           (ASNRS) (POTENTIALLY PROTECTIVE 63 KD ANTIGEN)
           >gi|627105|pir||A54510 63K antigen - nematode (Brugia
           malayi) >gi|156057|gb|AAA27852.1| (J03971) 63 kd antigen
           [Brugia malayi]
           Length = 548
           
 Score =  181 bits (454), Expect = 2e-44
 Identities = 129/435 (29%), Positives = 224/435 (50%), Gaps = 24/435 (5%)

Query: 17  KKVKVAGWVQEVKDLG-GIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVE 75
           ++V + GW+  ++  G  + F  +RD  G +QV     K+ Q    L   +N+E  + + 
Sbjct: 125 ERVCIKGWIHRMRRQGKSLMFFILRDGTGFLQVLL-MDKLCQTYDALT--VNTECTVEIY 181

Query: 76  GIVNFTPKAKL---GFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPR 132
           G +   P+ K    G E+I +  ++I  A  P  +D     +A +D  LDNR + +R   
Sbjct: 182 GAIKEVPEGKEAPNGHELIADFWKIIGNAP-PGGIDNVLNEEASVDKMLDNRHLVIRGEN 240

Query: 133 VMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFLAQSPQ 192
             ++ ++R++  RA RE FY  G++E+  P ++ T  EGG+ LF L YF   +FL QS Q
Sbjct: 241 AAALLRLRAAATRAMREHFYNAGYLEVAPPTLVQTQVEGGSTLFNLDYFGEQSFLTQSSQ 300

Query: 193 LYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLIL 252
           LY +  + T L  VF    + +  + + +  L E   ++AE  FI + +++M+ +E L+ 
Sbjct: 301 LYLETCIPT-LGDVFLHCSVLQGGKISHSSTLAEYAHVEAECPFI-TLDDLMEKIEELVC 358

Query: 253 YVINYVRENNE--KELKILEFELNEPKKPFPRITYDEALEIL------SDLGKEIPWGED 304
             ++ +  + E  K L+ +  +   P++PF R+ Y +A++ L      ++ G    +GED
Sbjct: 359 DTVDRLLADEEAKKLLEHINPKFQPPERPFLRMEYKDAIKWLQEHNVENEFGNTFTYGED 418

Query: 305 IDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGV-EIS 363
           I    E    ++M +     +  + R+PSE K FY+ +      + ++ DL   GV EI 
Sbjct: 419 IAEAAE----RFMTDTINKPI-LLNRFPSEIKAFYMQRDAQDNTLTESVDLLMPGVGEIV 473

Query: 364 SGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNI 423
            G  R  + D L +  +   ++P+ + +YL    YG  PHGG+GLG ER I  + +  +I
Sbjct: 474 GGSMRIWKFDELSKAFKNVEIDPKPYYWYLDQRLYGTCPHGGYGLGLERFICWLTNTNHI 533

Query: 424 REVILFPRDRRRLVP 438
           R+V L+PR   R VP
Sbjct: 534 RDVCLYPRFVGRCVP 548


>sp|P17242|SYN_ECOLI ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRNA LIGASE) (ASNRS)
           >gi|68529|pir||SYECNT asparagine--tRNA ligase (EC
           6.1.1.22) - Escherichia coli >gi|41000|emb|CAA48274.1|
           (X68192) Asparaginyl-tRNA synthetase [Escherichia coli]
           >gi|147935|gb|AAA24666.1| (M33145) asparaginyl-tRNA
           synthetase (asnS) [Escherichia coli]
           >gi|1651455|dbj|BAA35682.1| (D90731) Asparaginyl-tRNA
           synthetase (EC  6.1.1.22) (asparagine-tRNA ligase)
           (asnRS). [Escherichia coli] >gi|1787161|gb|AAC74016.1|
           (AE000195) asparagine tRNA synthetase [Escherichia coli
           K12]
           Length = 466
           
 Score =  180 bits (452), Expect = 3e-44
 Identities = 133/452 (29%), Positives = 213/452 (46%), Gaps = 43/452 (9%)

Query: 18  KVKVAGWVQEVKDL-GGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVEG 76
           +V V GWV+  +D   GI F+ + D      V A          + + +L +   ++V G
Sbjct: 19  EVTVRGWVRTRRDSKAGISFLAVYDGSCFDPVQAVINNSLPNYNEDVLRLTTGCSVIVTG 78

Query: 77  IVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPRVMSI 136
            V  +P     FEI   K+EV    + P    P    +  ++   +   +  R   + ++
Sbjct: 79  KVVASPGQGQQFEIQASKVEVAGWVEDP-DTYPMAAKRHSIEYLREVAHLRPRTNLIGAV 137

Query: 137 FKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLK----------------- 179
            ++R ++ +A   FF ++GF  + TP I A+ TEG  E+F +                  
Sbjct: 138 ARVRHTLAQALHRFFNEQGFFWVSTPLITASDTEGAGEMFRVSTLDLENLPRNDQGKVDF 197

Query: 180 ---YFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAF 236
              +F  ++FL  S QL  +   +  L K++  GP FRAE  NT+RHL E W ++ E+AF
Sbjct: 198 DKDFFGKESFLTVSGQLNGETY-ACALSKIYTFGPTFRAENSNTSRHLAEFWMLEPEVAF 256

Query: 237 IESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEP---------KKPFPRITYDE 287
               + +  L E ++ YV   V E    ++K     +++          +  F ++ Y +
Sbjct: 257 ANLND-IAGLAEAMLKYVFKAVLEERADDMKFFAERVDKDAVSRLERFIEADFAQVDYTD 315

Query: 288 ALEILSDLGKE----IPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKY 343
           A+ IL + G++    + WG D+ +E E+    Y+ E        +  YP + K FY+   
Sbjct: 316 AVTILENCGRKFENPVYWGVDLSSEHER----YLAEEHFKAPVVVKNYPKDIKAFYMRLN 371

Query: 344 EDKPEVCKAFDLEYRGV-EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPP 402
           ED   V  A D+   G+ EI  G QRE R D+L E++ E GLN E + +Y     YG  P
Sbjct: 372 EDGKTVA-AMDVLAPGIGEIIGGSQREERLDVLDERMLEMGLNKEDYWWYRDLRRYGTVP 430

Query: 403 HGGFGLGAERLIMRMLDIGNIREVILFPRDRR 434
           H GFGLG ERLI  +  + N+R+VI FPR  R
Sbjct: 431 HSGFGLGFERLIAYVTGVQNVRDVIPFPRTPR 462


>pir||T39675 asparaginyl-trna synthetase - fission yeast  (Schizosaccharomyces
           pombe) >gi|3850088|emb|CAA21915.1| (AL033389)
           asparaginyl-trna synthetase, cytoplasmic
           [Schizosaccharomyces pombe]
           Length = 568
           
 Score =  180 bits (452), Expect = 3e-44
 Identities = 127/438 (28%), Positives = 211/438 (47%), Gaps = 29/438 (6%)

Query: 18  KVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVEGI 77
           +V+V GWV  ++   GI FI +RD  G +Q     K   +  +  I  L  E  + + G+
Sbjct: 143 RVRVNGWVHRMRTQKGIIFIILRDGTGFLQCVLSGKVYDRASYDFI-NLGPESTVCLYGV 201

Query: 78  VNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGK--------VKAELDTRLDNRFMDLR 129
           +   P+ K      P   E++      L   PTG+         +AE    LD R + +R
Sbjct: 202 IKELPEGKSA----PGNHELVVDYYQILHAAPTGEEAFTNRLNAEAEPSYLLDQRHLVIR 257

Query: 130 NPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFLAQ 189
                S+ K+R+   RA R+ F      E+  P ++ T  EGG  LF   Y+  DA+L Q
Sbjct: 258 GETASSVLKVRARALRAMRDTFENLKMTEVTPPCMVQTQVEGGATLFKFNYYGQDAYLTQ 317

Query: 190 SPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLER 249
           S QLY +  +   L  V+ I   FRAE+  T RHL+E   ++ E+ F+ +  E ++++E 
Sbjct: 318 SSQLYLEAAL-PALGSVYTIQESFRAEKSLTRRHLSEFTHVEFELPFV-NFGEFLEIIEE 375

Query: 250 LILYVINYVREN--NEKELKILEFELNEPKKPFPRITYDEALE------ILSDLGKEIPW 301
            I   I+ + ++      +K L  +  +P +PF R++Y++A++      IL+  G++  +
Sbjct: 376 FICQTIDRLLDDPIATPLIKQLNPDFVKPSRPFMRLSYEDAIKYLNEHNILTPEGEQHKF 435

Query: 302 GEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGV- 360
           G+DI    E    + M +     ++  Y +P E K FY+ +  D+PE+ ++ D     V 
Sbjct: 436 GDDIAEAAE----RKMTDQINRPIFLTY-FPLEIKSFYMKRVVDRPELTESVDCLMPNVG 490

Query: 361 EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDI 420
           EI  G  R      L+   + +G++P  + ++    +YG   HGG GLG ER +  + D 
Sbjct: 491 EIVGGSMRISDIQELLAAYKREGIDPAPYYWFTEQRKYGTTEHGGCGLGLERFLAWLCDR 550

Query: 421 GNIREVILFPRDRRRLVP 438
             +RE  LFPR   R  P
Sbjct: 551 YTVRECCLFPRFTERCTP 568


>emb|CAB91185.1| (AL355921) asparaginyl-trna synthetase, mitochondrial
           [Schizosaccharomyces pombe]
           Length = 441
           
 Score =  180 bits (451), Expect = 4e-44
 Identities = 136/447 (30%), Positives = 219/447 (48%), Gaps = 61/447 (13%)

Query: 15  NGKKVKVAGWVQEVKDLGGIKFIWIRD---REGIVQVTAPKKKVPQEIFKLIPKLNSEDV 71
           NG+ + + GWV+ ++ L  + F  + D   ++ +  VT+P++           KL+    
Sbjct: 19  NGELISINGWVRSIRKLKNVCFAMVSDGTCQQALQVVTSPEQS---------KKLSYGAS 69

Query: 72  IVVEGIVNFTPKAKLG---FEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRF--M 126
           + +EG +  +  AKLG   +E++ EK+++  +       D     K  L T +  +   +
Sbjct: 70  VNIEGQLAVSKNAKLGLQQYELLAEKIKIYGQIND----DNYPIQKKHLTTEMLRQIPHL 125

Query: 127 DLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLK------- 179
            LR  +   IF++RS   +A R+FF  + F E + P I ++  EG  E+F L        
Sbjct: 126 RLRTAKQGEIFRLRSDSLKALRQFFSSKDFTETNPPIITSSDCEGAGEVFTLTPQETHKN 185

Query: 180 ----------YFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWS 229
                     +F+  AFL  S QL+ + + + GL +V+ I P FRAE+ +T+RHL E W 
Sbjct: 186 KSFERDDQKHFFDRPAFLTVSTQLHLEAL-ALGLSRVYTISPAFRAEQSHTSRHLAEFWM 244

Query: 230 IDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEAL 289
           ++AE+AF+ S  ++  L+E +I Y +N + E N           ++  KP+  +TY EA+
Sbjct: 245 LEAEVAFMTSLSQLTSLMEDMIKYTLNSLMEQNYH-----RDHWDQLLKPWKCMTYSEAI 299

Query: 290 EILSDLGK--EIP--WGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYED 345
           E LS + K  + P  WG D+ +E E    KY+ E       F+  YP + KPFY+     
Sbjct: 300 EELSAVKKTWKYPPKWGNDLSSEHE----KYLCEILHKTPVFVTDYPQKIKPFYMK--SS 353

Query: 346 KPEVCKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGG 405
            P+   A DL    V   +GG     H      + E    P   ++YL   +Y   PHGG
Sbjct: 354 GPDTVAAVDLLVPQVGELAGGSLRKDH------LDEYKTYPPELQWYLDLMKYSNAPHGG 407

Query: 406 FGLGAERLIMRML-DIGNIREVILFPR 431
           FGLG ERLI  +  +  N++E I FPR
Sbjct: 408 FGLGIERLIAFLEGENTNVKETIPFPR 434


>pir||A28209 60K filarial antigen - nematode (Brugia malayi)
           >gi|156053|gb|AAA27849.1| (J03266) 63kd antigen [Brugia
           malayi]
           Length = 548
           
 Score =  179 bits (450), Expect = 5e-44
 Identities = 128/435 (29%), Positives = 224/435 (51%), Gaps = 24/435 (5%)

Query: 17  KKVKVAGWVQEVKDLG-GIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVE 75
           ++V + GW+  ++  G  + F  +RD  G +QV     K+ Q    L   +N+E  + + 
Sbjct: 125 ERVCIKGWIHRMRRQGKSLMFFILRDGTGFLQVLL-MDKLCQTYDALT--VNTECTVEIY 181

Query: 76  GIVNFTPKAKL---GFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPR 132
           G +   P+ K    G E+I +  ++I  A +   +D     +A +D  LDNR + +R   
Sbjct: 182 GAIKEVPEGKEAPNGHELIADFWKIIGNAPSG-GIDNVLNEEASVDKMLDNRHLVIRGEN 240

Query: 133 VMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFLAQSPQ 192
             ++ ++R++  RA RE FY  G++E+  P ++ T  EGG+ LF L YF   +FL QS Q
Sbjct: 241 AAALLRLRAAATRAMREHFYNAGYVEVAPPTLVQTQVEGGSTLFNLDYFGEQSFLTQSSQ 300

Query: 193 LYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLIL 252
           LY +  + T L  VF    + +  + + +  L E   ++AE  FI + +++M+ +E L+ 
Sbjct: 301 LYLETCIPT-LGDVFLHCSVLQGGKISHSSTLAEYAHVEAECPFI-TLDDLMEKIEELVC 358

Query: 253 YVINYVRENNE--KELKILEFELNEPKKPFPRITYDEALEIL------SDLGKEIPWGED 304
             ++ +  + E  K L+ +  +   P++PF R+ Y +A++ L      ++ G    +GED
Sbjct: 359 DTVDRLLADEEAKKLLEHINPKFQPPERPFLRMEYKDAIKWLQEHNVENEFGNTFTYGED 418

Query: 305 IDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGV-EIS 363
           I    E    ++M +     +  + R+PSE K FY+ +      + ++ DL   GV EI 
Sbjct: 419 IAEAAE----RFMTDTINKPI-LLNRFPSEIKAFYMQRDAKDNTLTESVDLLMPGVGEIV 473

Query: 364 SGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNI 423
            G  R  + D L +  +   ++P+ + +YL    YG  PHGG+GLG ER I  + +  +I
Sbjct: 474 GGSMRIWKFDELSKAFKNVEIDPKPYYWYLDQRLYGTCPHGGYGLGLERFICWLTNTNHI 533

Query: 424 REVILFPRDRRRLVP 438
           R+V L+PR   R VP
Sbjct: 534 RDVCLYPRFVGRCVP 548


>sp|P52276|SYN_SYNY3 PROBABLE ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRNA LIGASE)
           (ASNRS) >gi|7437579|pir||S75997 asparagine--tRNA ligase
           (EC 6.1.1.22) - Synechocystis sp.  (strain PCC 6803)
           >gi|1001357|dbj|BAA10844.1| (D64006) asparaginyl-tRNA
           synthetase [Synechocystis sp.]
           Length = 513
           
 Score =  178 bits (447), Expect = 1e-43
 Identities = 123/446 (27%), Positives = 207/446 (45%), Gaps = 40/446 (8%)

Query: 18  KVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVEGI 77
           +V V GW++  + L    F+ + D   +  +         +  +L+ +L +   +VVEG 
Sbjct: 69  QVMVQGWLRTKRTLKDFSFVEVNDGSSLANLQVVLDGSLADYDRLLSQLQTGAALVVEGK 128

Query: 78  VNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPRVMSIF 137
           +  +P      E+   KLE++  A       P  K +   +       +  R   + ++ 
Sbjct: 129 LAPSPGKGQRVELKATKLELLGGADPGSY--PLQKKRHSFEFLRTIGHLRPRTNTIGAVM 186

Query: 138 KIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLK------------------ 179
           ++R++   A  +FF + GF+ +HTP I A+  EG  +LF +                   
Sbjct: 187 RVRNACATAIHQFFQERGFLWVHTPIITASDCEGAGDLFKVTTLDLQRVPKNGEGIDYSQ 246

Query: 180 -YFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIE 238
            +F   A+L  S QL  ++M +     V+  GP FRAE  NT+RHL E W ++ EMAF +
Sbjct: 247 DFFGKQAYLTVSGQLEAEVM-ALAFQNVYTFGPTFRAENSNTSRHLAEFWMVEPEMAFCD 305

Query: 239 SEEEVMDLLERLILYVINYVRENNEKELKILEFELNEP---------KKPFPRITYDEAL 289
            E +     E  + Y+  +V E   ++++  +  ++              F  +TY EA+
Sbjct: 306 LEGD-RQWAEEFLKYIFKFVLEKCPEDMEFFDQRIDNTVLATADNIINNEFAWLTYSEAI 364

Query: 290 EILSDLGKE----IPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYED 345
           ++L    ++    + WG D+ +E E+    Y+ E        +  YP + K FY+   +D
Sbjct: 365 KLLEKADQKFEYPVAWGVDLQSEHER----YLAETVFKRPTIVTDYPKDIKAFYMRLNDD 420

Query: 346 KPEVCKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGG 405
              V     L  +  EI  G QRE R DIL ++++E+G+  E   +YL    YG  PH G
Sbjct: 421 GKTVAAMDILAPKIGEIIGGSQREERLDILTQRMQEQGVPEEDLWWYLDLRRYGSVPHAG 480

Query: 406 FGLGAERLIMRMLDIGNIREVILFPR 431
           FGLG ER++  M  + NIR+VI FPR
Sbjct: 481 FGLGFERIVQFMTGMANIRDVIPFPR 506


>pir||E82217 asparaginyl-tRNA synthetase VC1297 [imported] - Vibrio cholerae
           (group O1 strain N16961) >gi|9655785|gb|AAF94456.1|
           (AE004209) asparaginyl-tRNA synthetase [Vibrio cholerae]
           Length = 481
           
 Score =  178 bits (447), Expect = 1e-43
 Identities = 131/465 (28%), Positives = 215/465 (46%), Gaps = 48/465 (10%)

Query: 10  ITEELNGK-----KVKVAGWVQEVKDL-GGIKFIWIRDREGIVQVTAPKKKVPQEIFKLI 63
           + + L+GK     +V V GW++  +D   GI F+ I D      + A            +
Sbjct: 21  VNDVLSGKLAVDSEVTVRGWIRTRRDSKAGISFLAIYDGSCFNPIQAVVPNNLNNYDNEV 80

Query: 64  PKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDN 123
            KL +   + V G +  +P +   FE+    ++V+   +      P  K +  ++   + 
Sbjct: 81  LKLTTGCSVEVTGKIVESPASGQAFELAASDVKVVGWVEDA-DTYPMAKTRHSIEYLREV 139

Query: 124 RFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLK---- 179
             +  R   + ++ ++R+ + +A   F++++G+  +  P I A+  EG  E+F +     
Sbjct: 140 AHLRPRTNVIGAVARVRNCLAQAIHRFYHEQGYFWVSAPLITASDAEGAGEMFRVSTLDM 199

Query: 180 ----------------YFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRH 223
                           +F  + FL  S QL  +   +  + KV+  GP FRAE  NT+RH
Sbjct: 200 ENLPRTDAGKVDYNQDFFGKETFLTVSGQLNAEAY-ACAISKVYTFGPTFRAENSNTSRH 258

Query: 224 LNEAWSIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEP------- 276
           L E W ++ E+AF +    V  L E ++ YV   V      +L+     +N         
Sbjct: 259 LAEFWMVEPEVAFADLNT-VAKLAEDMLKYVFKAVLAERRDDLEFFNDRINNEVIARLEQ 317

Query: 277 --KKPFPRITYDEALEILSDLGKE----IPWGEDIDTEGEKLLGKYMLENEGAELYFIYR 330
             +  F ++ Y +A+EIL + GK     + WG D+ +E E+ L     E        +  
Sbjct: 318 FVESDFAQVDYTDAIEILKNCGKTFEFPVEWGIDLASEHERFLA----EEHFKAPVIVKN 373

Query: 331 YPSEAKPFYIMKYEDKPEVCKAFDLEYRGV-EISSGGQREHRHDILVEQIREKGLNPESF 389
           YP + K FY+   ED   V  A D+   G+ EI  G QRE R DIL  ++RE G++PE  
Sbjct: 374 YPKDIKAFYMRMNEDGKTVA-AMDVLAPGIGEIIGGSQREERLDILDARMREFGIDPEHM 432

Query: 390 EFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRR 434
           ++Y     YG  PH GFGLG ERL+  +  +GN+R+VI FPR  R
Sbjct: 433 DWYRDLRRYGTVPHAGFGLGFERLVSYVTGMGNVRDVIPFPRTPR 477


>sp|O67589|SYD_AQUAE ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
           >gi|7437585|pir||D70445 aspartate--tRNA ligase (EC
           6.1.1.12) - Aquifex aeolicus >gi|2984003|gb|AAC07548.1|
           (AE000750) aspartyl-tRNA synthetase [Aquifex aeolicus]
           Length = 603
           
 Score =  171 bits (430), Expect = 1e-41
 Identities = 122/302 (40%), Positives = 169/302 (55%), Gaps = 36/302 (11%)

Query: 3   RTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKL 62
           RT Y  E++EE  GK+VK+AGWV   +  GG+ FI +RDREGIVQV   +K  P E +++
Sbjct: 10  RTKYCGEVSEEDIGKEVKLAGWVHRKRHHGGVIFIDLRDREGIVQVVVEEKTNP-EAYEV 68

Query: 63  IPKLNSEDVIVVEGIV------NFTPKAKLGF-EIIPEKLEVISKAKT-PLPLDPTGKVK 114
             KL SE VI V G V         PK K G+ E++ +++ V + ++  P P++    V 
Sbjct: 69  ADKLKSEYVIGVVGKVRKRPEGTENPKLKTGYVEVVADRILVFNTSEALPFPVEEETHVS 128

Query: 115 AELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGG-- 172
            E  T+L  R++DLR   + +    R  V++ TR FF KEGFIEI TP +  +  EG   
Sbjct: 129 EE--TKLKYRYIDLRRESMKNNLIFRHRVYQITRNFFTKEGFIEIETPFLTKSTPEGARD 186

Query: 173 ----TELFPLKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAW 228
               + L P K++     L QSPQL+KQ++M  G D+ F+I   FR E+    R   E  
Sbjct: 187 FLVPSRLHPGKFYA----LPQSPQLFKQILMIAGFDRYFQIVKCFRDEDLRADRQ-PEFT 241

Query: 229 SIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEA 288
            ID EM+F+ SEEEVMD+ ERLI  +         KEL  +E      K PF RI+Y EA
Sbjct: 242 QIDYEMSFV-SEEEVMDVAERLIATLF--------KELLGVEL-----KTPFERISYREA 287

Query: 289 LE 290
           +E
Sbjct: 288 ME 289


 Score = 70.2 bits (169), Expect = 4e-11
 Identities = 74/303 (24%), Positives = 123/303 (40%), Gaps = 63/303 (20%)

Query: 194 YKQMMMSTGLDK--------VFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMD 245
           Y++ M   G DK        + E+  IF+       + + EA  I   + F  S     +
Sbjct: 284 YREAMEKYGTDKPDRRFGLELIELTDIFKNTAFKVFKSVVEAGGIIKAINFKGS-----N 338

Query: 246 LLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIP----- 300
           L  + I  +  +V+    K L  ++ E ++   P  +   +E  + L +  K  P     
Sbjct: 339 LSRKEIDELTKFVQSLGAKGLAWIKVEKDKLTSPIVKFFTEEETQKLLERTKAEPGDVIL 398

Query: 301 WGEDIDTEGEKLLG--------KYMLENEGA-ELYFIYRYP------------SEAKPFY 339
           +  D      K+LG        KY L +E   ++++I  +P            S   PF 
Sbjct: 399 FSADKKEMVYKILGNLRLHLGKKYKLIDESKWDVFWIVDFPLMEWDEEEERFVSLHHPFT 458

Query: 340 IMKYEDKPEV--------------------CKAFDLEYRGVEISSGGQREHRHDILVEQI 379
           + + E+ P++                     +A+D+   G EI  G  R HR DI     
Sbjct: 459 MPREENIPKLKEALEEEDLEKKKEIVHSVRARAYDMVLNGEEIGGGSIRIHRRDIQEVVF 518

Query: 380 REKGLNP----ESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRRR 435
           +  G+      E F F L A +YG PPHGG   G +R++  ML + +IR+ I FP+ +R 
Sbjct: 519 KLLGIGEVEAQEKFGFLLEALKYGAPPHGGLAFGLDRVVALMLGLDSIRDTIAFPKTQRG 578

Query: 436 LVP 438
           + P
Sbjct: 579 ICP 581


>emb|CAA10904.1| (AJ222644) asparaginyl-tRNA synthetase [Arabidopsis thaliana]
           Length = 566
           
 Score =  171 bits (428), Expect = 2e-41
 Identities = 128/460 (27%), Positives = 215/460 (45%), Gaps = 52/460 (11%)

Query: 16  GKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIP-KLNSEDVIVV 74
           G+ + + GWV+ ++    + FI I D   +  +        +   ++    + +   + V
Sbjct: 108 GQSLNIMGWVRTLRSQSSVTFIEINDGSCLSNLQCVMTSDAEGYDQVESGSILTGASVSV 167

Query: 75  EGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPRVM 134
           +G +  +   K   E+  EK+ V+ +  +  P+      +  L T+   R    R     
Sbjct: 168 QGTIVASQGTKQKVELKVEKIIVVGECDSSYPIQKKRVSREFLRTKAHLR---PRTNTFG 224

Query: 135 SIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLK--------------- 179
           ++ ++R+++  AT +FF + GF+ + +P I A+  EG  E F +                
Sbjct: 225 AVARVRNTLAYATHKFFQESGFVWVASPIITASDCEGAGEQFCVTTLIPSSHEYTDTSID 284

Query: 180 ---------------YFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHL 224
                          +F   AFL  S QL  +   +T L  V+  GP FRAE  NT+RHL
Sbjct: 285 AIPKTKGGLIDWSQDFFGKPAFLTVSGQLNGETY-ATALSDVYTFGPTFRAENSNTSRHL 343

Query: 225 NEAWSIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNE--------- 275
            E W I+ E+AF + +++ M      + YV+ YV +N +++++  +  + +         
Sbjct: 344 AEFWMIEPELAFADLDDD-MACATAYLQYVVKYVLDNCKEDMEFFDTWIEKGIIRRLSDV 402

Query: 276 PKKPFPRITYDEALEILSDLGKE----IPWGEDIDTEGEKLLGKYMLENEGAELYFIYRY 331
            +K F ++ Y +A+EIL    K+    + WG D+ +E E+ + +   E  G     I  Y
Sbjct: 403 AEKEFLQLGYTDAIEILLKANKKFDFPVKWGLDLQSEHERYITE---EAFGGRPVIIRDY 459

Query: 332 PSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPESFEF 391
           P E K FY+ + +D   V     L  R  E+  G QRE R ++L  ++ E  LN ES+ +
Sbjct: 460 PKEIKAFYMRENDDGKTVAAMDMLVPRIGELIGGSQREERLEVLEARLDELKLNKESYWW 519

Query: 392 YLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPR 431
           YL    YG  PH GFGLG ERL+  +  I NIR+VI FPR
Sbjct: 520 YLDLRRYGSVPHAGFGLGFERLVQFVTGIDNIRDVIPFPR 559


>sp|O51128|SYN_BORBU ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRNA LIGASE) (ASNRS)
           >gi|7437580|pir||E70112 asparagine--tRNA ligase (EC
           6.1.1.22) asnS - Lyme disease spirochete
           >gi|2687998|gb|AAC66501.1| (AE001123) asparaginyl-tRNA
           synthetase (asnS) [Borrelia burgdorferi]
           Length = 466
           
 Score =  168 bits (420), Expect = 2e-40
 Identities = 130/452 (28%), Positives = 205/452 (44%), Gaps = 43/452 (9%)

Query: 19  VKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF-KLIPKLNSEDVIVVEGI 77
           V + GW++  +  G I FI I D   +  + A   +   +   K + KL +   I + G+
Sbjct: 22  VTINGWIRTKRSNGKIGFIEINDGSTLKGIQAVINEEENQFSEKDLKKLTTGTSISLTGL 81

Query: 78  VNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPRVMSIF 137
           +  +P     +EI      VI +  T     P  K +   +   +   + +R     +I 
Sbjct: 82  LVESPAKGQNYEIKTHSFNVIGE--TDPETYPLQKKRHSFEFLREIPHLRIRTNTFGAIA 139

Query: 138 KIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLK------------------ 179
           ++R+ +     E+F K GF  I+TP I +   EG  E+F +                   
Sbjct: 140 RVRNKISYKIHEYFQKNGFFYINTPIITSNDGEGAGEMFRVSTLKFNKLNNALSNIDFKD 199

Query: 180 -YFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIE 238
            +F  +AFL+ + QL+ +   +  L K++  GP FRAE  NTTRH +E W I+ EMAF +
Sbjct: 200 DFFGKEAFLSVTGQLHGEAY-AMALSKIYTFGPTFRAENSNTTRHASEFWMIEPEMAFYK 258

Query: 239 SEEEVMDLLERLILYVINYVRENNEKELKILEFEL---------NEPKKPFPRITYDEAL 289
             + +  L E L+ Y+++ +     +++  LE  +         N     F  ITY +A+
Sbjct: 259 LNDNIA-LAEDLLKYLLSSILNECSQDMDFLENYIEKGLIKKLENVINSNFEVITYTKAI 317

Query: 290 EILSDLGKEIP----WGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYED 345
           EIL +  K       WG D+ T+ E+    Y+ E    +   +  YP   K FY+   +D
Sbjct: 318 EILENSKKNFEIKPYWGIDLQTDHER----YLTEETFKKPVVVIDYPKNFKAFYMKANKD 373

Query: 346 KPEVCKAFDLEYRGV-EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHG 404
              V K  D+    + EI  G +RE     L  +I+E  LN E   +YL    +G  PH 
Sbjct: 374 NKTV-KGMDILVPKIGEIIGGSEREDDLQKLENRIKELNLNIEHLNWYLDLRRFGSAPHS 432

Query: 405 GFGLGAERLIMRMLDIGNIREVILFPRDRRRL 436
           GFGLG ERL+     I NIR+ I FPR  + L
Sbjct: 433 GFGLGLERLVQYSTGISNIRDSIPFPRTPKNL 464


>pir||F82540 asparaginyl-tRNA synthetase XF2563 [imported] - Xylella fastidiosa
           (strain 9a5c) >gi|9107777|gb|AAF85360.1|AE004064_2
           (AE004064) asparaginyl-tRNA synthetase [Xylella
           fastidiosa]
           Length = 466
           
 Score =  166 bits (415), Expect = 6e-40
 Identities = 128/455 (28%), Positives = 211/455 (46%), Gaps = 51/455 (11%)

Query: 16  GKKVKVAGWVQEVKDL-GGIKFIWIRDRE--GIVQVTAPKKKVPQEIFKLIPKLNSEDVI 72
           G +V V GWV+  +D   G+ F+ + D      +QV  P      E    + KL +   +
Sbjct: 17  GSEVTVRGWVRTRRDSKAGLSFVSVSDGSCFAAIQVVTPAHLPNYETE--VRKLTTGCAV 74

Query: 73  VVEGIVNFTPKAKLGFEIIPEKLEVISKAKTP--LPLDPTGKVKAELDTRLDNRFMDLRN 130
           +V G +  +      FEI  + +EV+   + P   P+ P    +  L+   +   +  R 
Sbjct: 75  IVIGTLAPSLGQGQQFEIQAQSIEVVGWVEDPETYPIQPK---QHSLEFLREVAHLRPRT 131

Query: 131 PRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLK----------- 179
               ++ +IR  + +A   FF++ G+  I TP I  +  EG  ++F +            
Sbjct: 132 NLFGAVARIRHCLSQAVHRFFHENGYYWITTPIITTSDAEGAGQMFRVSTLDLVNLPRTE 191

Query: 180 ---------YFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSI 230
                    +F  + FL  S QL  +   +  L KV+  GP FRAE  +T RHL E W I
Sbjct: 192 TGGIDFSHDFFGKETFLTVSGQLNVEAY-ALALSKVYTFGPTFRAENSHTPRHLAEFWMI 250

Query: 231 DAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEP---------KKPFP 281
           + E+AF +  E+   + E+ + ++   V E    +L  +   + +          K PF 
Sbjct: 251 EPEIAFADLAEDAR-VAEQFLKFLFKTVLEERTDDLAFITERVEKTTISKLEGFIKSPFE 309

Query: 282 RITYDEALEILSDLGKE----IPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKP 337
           RI Y +A+++L   GK+    + WG D+ TE E+    ++ E        +  YP   K 
Sbjct: 310 RIEYTDAIKLLERSGKKFDFPVEWGLDLQTEHER----WLTEKHIGRPVVVTNYPEHIKA 365

Query: 338 FYIMKYEDKPEVCKAFDLEYRGV-EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAF 396
           FY M+  D  +   A D+   G+ EI  G QRE R ++L  ++ + GL+P  +++Y    
Sbjct: 366 FY-MRLNDDGKTVAAMDVLAPGIGEIIGGSQREERLEMLDIRMAQFGLDPTHYQWYRDFR 424

Query: 397 EYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPR 431
            YG  PH GFGLG ERL++ +  + NIR+ I +PR
Sbjct: 425 RYGSVPHAGFGLGFERLMVYVCGLSNIRDAIPYPR 459


>sp|O32038|SYD_BACSU ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
           >gi|7437581|pir||D69591 aspartate--tRNA ligase (EC
           6.1.1.12) aspS - Bacillus subtilis
           >gi|2635219|emb|CAB14714.1| (Z99118) aspartyl-tRNA
           synthetase [Bacillus subtilis]
           Length = 592
           
 Score =  160 bits (401), Expect = 3e-38
 Identities = 104/296 (35%), Positives = 165/296 (55%), Gaps = 25/296 (8%)

Query: 3   RTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKL 62
           RT+Y  +ITE+  G+ V + GWVQ+ +DLGG+ FI +RDR GIVQV      V +E   +
Sbjct: 4   RTYYCGDITEKAIGESVTLKGWVQKRRDLGGLIFIDLRDRTGIVQVVF-NPDVSKEALAI 62

Query: 63  IPKLNSEDVIVVEGIV------NFTPKAKLG-FEIIPEKLEVISKAKTPLPLDPTGKVKA 115
              + +E V+ ++G V         P  K G  EI  + + V++ AKTP         + 
Sbjct: 63  AEGIRNEYVLDIQGKVVAREEGTVNPNLKTGAIEIHADGVNVLNAAKTPPFAISDQAEEV 122

Query: 116 ELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTE- 174
             D RL +R++DLR P +    ++R +V +A R F  + GF++I TP +  +  EG  + 
Sbjct: 123 SEDVRLKHRYLDLRRPAMFQTMQLRHNVTKAVRSFLDENGFLDIETPILTGSTPEGARDY 182

Query: 175 LFPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAE 233
           L P +  E + + L QSPQL+KQ++M +G+++ ++I   FR E+    R   E   ID E
Sbjct: 183 LVPSRVHEGEFYALPQSPQLFKQLLMVSGIERYYQIARCFRDEDLRADRQ-PEFTQIDIE 241

Query: 234 MAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEAL 289
           M+F+ S+E++M L E ++  V   +RE   +EL++          P PR+TYDEA+
Sbjct: 242 MSFM-SQEDIMSLAEEMMAKV---MRETKGEELQL----------PLPRMTYDEAM 283


>sp|P56459|SYD_HELPY ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
           >gi|7437582|pir||A64597 aspartate--tRNA ligase (EC
           6.1.1.12) - Helicobacter pylori  (strain 26695)
           >gi|2313739|gb|AAD07682.1| (AE000576) aspartyl-tRNA
           synthetase (aspS) [Helicobacter pylori 26695]
           Length = 577
           
 Score =  159 bits (397), Expect = 8e-38
 Identities = 111/299 (37%), Positives = 164/299 (54%), Gaps = 32/299 (10%)

Query: 2   LRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTA-PKKKVPQEIF 60
           +R+H+ +EI+E+  GK VKVAGW    +D GG+ FI +RD+ G+VQ+   P  K  ++  
Sbjct: 1   MRSHFCTEISEKDVGKIVKVAGWCNTYRDHGGVVFIDLRDKSGLVQLVCDPSSKAYEKAL 60

Query: 61  KLIPKLNSEDVIVVEGIVNF------TPKAKLG-FEIIPEKLEVISKAKTPLPLDPTGKV 113
           ++     SE V+V +G V         PK K G  EI+ E+L + +K+ TP P++  G  
Sbjct: 61  EV----RSEFVLVAKGKVRLRGAGLENPKLKTGKIEIVLEELIIENKSATP-PIE-IGNK 114

Query: 114 KAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGT 173
               D RL  R++DLR+P    IFK+RS V   TR    ++GF+EI TP +  T  EG  
Sbjct: 115 HVNEDLRLKYRYLDLRSPNSYEIFKLRSEVALITRNTLAQKGFLEIETPILSKTTPEGAR 174

Query: 174 E-LFPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSID 231
           + L P +  E + F L QSPQL+KQ++M  G+D+ F+I   FR E+    R   E   ID
Sbjct: 175 DYLVPSRVHEGEFFALPQSPQLFKQLLMVGGMDRYFQIARCFRDEDLRADRQ-PEFTQID 233

Query: 232 AEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALE 290
           AEM+F + E +VM ++E L+  +   V               +   KPF R+ Y EA+E
Sbjct: 234 AEMSFCD-ENDVMGVVEDLLQEIFKAVG--------------HTISKPFKRMPYKEAME 277


>sp|P57441|SYN_BUCAI ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRNA LIGASE) (ASNRS)
           >gi|10039030|dbj|BAB13064.1| (AP001119) asparaginyl-tRNA
           synthetase [Buchnera sp. APS]
           Length = 466
           
 Score =  157 bits (394), Expect = 2e-37
 Identities = 130/448 (29%), Positives = 197/448 (43%), Gaps = 43/448 (9%)

Query: 19  VKVAGWVQEVKDL-GGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVEGI 77
           + V GWV+  +    G  FI I D      +           +K I  L +   +++ G 
Sbjct: 20  ITVCGWVRNRRSSKSGFSFITIYDGSCFNSIQVIANNTLPNYYKEILHLTTGCSVMLSGK 79

Query: 78  VNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPRVMSIF 137
           +  +   K  +EI  +K++V+   + P    P    K   +   +   +  R   + +I 
Sbjct: 80  LILSIGDKQKYEIQLKKIKVLGWVENPETY-PISSKKHSTEYLREVAHLRSRTNLIGAIA 138

Query: 138 KIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLK------------------ 179
           +IR+ +  +   FFYKE +  + TP I +  TEG  E+F +                   
Sbjct: 139 RIRNYILHSLHHFFYKEKYYWVPTPIITSLNTEGAGEMFRVSTLDMENIPKNLDSSVDFK 198

Query: 180 --YFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFI 237
             +F  ++FL  S QL  +   +  L KV+  GP FRAE  NT RHL E W ++ E AF 
Sbjct: 199 KDFFGKESFLTVSGQLNLETY-ACSLSKVYTFGPTFRAENSNTGRHLAEFWMLEVESAFT 257

Query: 238 ESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEP---------KKPFPRITYDEA 288
           +  + + D  E ++ YV   + +    ++  LE   N              F RI Y E 
Sbjct: 258 DLND-ISDFAECMLKYVCKSLLKKCITDINFLENYTNSNIVDRLEKFLLVDFVRIDYVEV 316

Query: 289 LEILSD----LGKEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYE 344
           + IL D        +  G D+ +E E+    +++EN       +  YP E K FY+    
Sbjct: 317 INILLDSKIKFNNSVFLGIDLSSEHER----FLVENYFKIPVIVKNYPKELKAFYMRLNN 372

Query: 345 DKPEVCKAFDLEYRGV-EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPH 403
           DK  V  A D+    V E+  G QRE R  IL E++ E GL  E + +Y     YG  PH
Sbjct: 373 DKKTVA-AIDILVPNVGELIGGSQREERIAILDERLLELGLKKEDYWWYRDLRRYGTVPH 431

Query: 404 GGFGLGAERLIMRMLDIGNIREVILFPR 431
            GFG+G ERLI     I NIR++I FPR
Sbjct: 432 SGFGMGFERLISYFTGITNIRDLIPFPR 459


>sp|Q9X1F4|SYD_THEMA ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
           >gi|7437606|pir||F72252 aspartate--tRNA ligase (EC
           6.1.1.12) - Thermotoga maritima  (strain MSB8)
           >gi|4982006|gb|AAD36510.1|AE001796_2 (AE001796)
           aspartyl-tRNA synthetase [Thermotoga maritima]
           Length = 579
           
 Score =  157 bits (393), Expect = 2e-37
 Identities = 104/303 (34%), Positives = 166/303 (54%), Gaps = 38/303 (12%)

Query: 1   MLRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF 60
           MLRTH   E+     GKKVK+ GWV  ++DLGG++FI +RDR G  Q+      V  E +
Sbjct: 1   MLRTHTCGELRATDEGKKVKLCGWVDRIRDLGGVRFIDLRDRYGETQIVC---DVNSEAY 57

Query: 61  KLIPKLNSEDVIVVEGIVNFTPKAKLG-------FEIIPEKLEVISKAKTPLPLDPTGKV 113
            ++ +L  E V++VEG V   P+            E++ E++E++S A  PLP  P    
Sbjct: 58  SVVDELTRESVVLVEGTVRKRPEGTENPNIETGEIEVVAERIEILSLA-DPLPFYPGETP 116

Query: 114 KAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGG- 172
           K E+  RL  R++DLR+ R+     +R  + +  R++F + GF+EI TP +  +  EG  
Sbjct: 117 KEEM--RLKYRYIDLRSERMKRNIILRYRISKIIRDYFDELGFLEIETPFLTRSTPEGAR 174

Query: 173 -----TELFPLKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEA 227
                + L P K++     L QSPQL+KQ++M +G D+ F+I   FR E+    R   E 
Sbjct: 175 DFLVPSRLRPGKFYA----LPQSPQLFKQILMISGFDRYFQIVRCFRDEDLRADRQ-PEF 229

Query: 228 WSIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDE 287
             +D EM+F++  E+V+++ E ++  V    +E++  +LK+          PF RI YD+
Sbjct: 230 TQVDVEMSFVD-VEDVLNVSEGMVSRVF---KESSGIDLKV----------PFDRIPYDD 275

Query: 288 ALE 290
           A+E
Sbjct: 276 AME 278


 Score = 71.8 bits (173), Expect = 1e-11
 Identities = 42/110 (38%), Positives = 57/110 (51%), Gaps = 5/110 (4%)

Query: 327 FIYRYPSEAKPFYIMKYEDKPEV-CKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLN 385
           F+ R+     P      +D  +V  KA+DL   G E+  G  R HR DI  +     GL+
Sbjct: 440 FVARHHPFTMPVLETLGDDYTKVRAKAYDLVINGYEVGGGSIRIHRRDIQEKIFELLGLS 499

Query: 386 PES----FEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPR 431
            E     F F+L AF YG+PPHGG   G +RL+  +    +IREVI FP+
Sbjct: 500 EEEAQKKFGFFLEAFRYGVPPHGGIAFGLDRLVSIIAGESSIREVIAFPK 549


>sp|Q9ZLL9|SYD_HELPJ ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
           >gi|7437600|pir||C71916 aspartate--tRNA ligase (EC
           6.1.1.12) - Helicobacter pylori  (strain J99)
           >gi|4155111|gb|AAD06143.1| (AE001489) ASPARTYL-TRNA
           SYNTHETASE [Helicobacter pylori J99]
           Length = 579
           
 Score =  155 bits (389), Expect = 7e-37
 Identities = 108/299 (36%), Positives = 163/299 (54%), Gaps = 32/299 (10%)

Query: 2   LRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQ-VTAPKKKVPQEIF 60
           +R+H+ +EI+E+  GK +KVAGW    +D GG+ FI +RD+ G+VQ V  P  K  ++  
Sbjct: 1   MRSHFCTEISEKDVGKTIKVAGWCNTYRDHGGVVFIDLRDKSGLVQLVCDPSSKAYEKAL 60

Query: 61  KLIPKLNSEDVIVVEGIVNF------TPKAKLG-FEIIPEKLEVISKAKTPLPLDPTGKV 113
               ++ SE V+V +G           PK K G  EI+ E+L + +K+ TP P++  G  
Sbjct: 61  ----EVRSEFVLVAKGKARLRGAGLENPKLKTGKIEIVLEELVIENKSATP-PIE-IGNK 114

Query: 114 KAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGT 173
               D RL  R++DLR+     IFK+RS V   TR    ++GF+EI TP +  T  EG  
Sbjct: 115 SVNEDLRLKYRYLDLRSLNAYEIFKLRSEVALITRNALAQKGFLEIETPILSKTTPEGAR 174

Query: 174 E-LFPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSID 231
           + L P +  E + F L QSPQL+KQ++M  G+D+ F+I   FR E+    R   E   ID
Sbjct: 175 DYLVPSRVHEGEFFALPQSPQLFKQLLMVGGMDRYFQIARCFRDEDLRADRQ-PEFTQID 233

Query: 232 AEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALE 290
           AEM+F + E++VM ++E L+  +   +               +   KPF R+ Y EA+E
Sbjct: 234 AEMSFCD-EDDVMGVVEDLLQEIFKAIG--------------HTISKPFKRMPYKEAME 277


 Score = 69.1 bits (166), Expect = 1e-10
 Identities = 40/112 (35%), Positives = 61/112 (53%), Gaps = 8/112 (7%)

Query: 331 YPSEAKPFYIMKY---EDKPEV-CKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNP 386
           Y +   PF + K    ED  E+   A+D+   GVE+  G  R H+ ++  +   +  +N 
Sbjct: 440 YHAAHHPFTMPKNIECEDIEEIEAHAYDVVLNGVELGGGSIRIHKEEMQKKVFEKININE 499

Query: 387 ES----FEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRR 434
           E     F F L A ++G PPHGGF +G +RLIM M    +IR+VI FP+ ++
Sbjct: 500 EEAQKKFGFLLEALKFGAPPHGGFAIGFDRLIMLMTKSNSIRDVIAFPKTQK 551


>sp|P36419|SYD_THETH ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
           >gi|420805|pir||S33743 aspartate--tRNA ligase (EC
           6.1.1.12) - Thermus aquaticus >gi|9257069|pdb|1EFW|A
           Chain A, Crystal Structure Of Aspartyl-Trna Synthetase
           From Thermus Thermophilus Complexed To Trnaasp From
           Escherichia Coli >gi|9257070|pdb|1EFW|B Chain B, Crystal
           Structure Of Aspartyl-Trna Synthetase From Thermus
           Thermophilus Complexed To Trnaasp From Escherichia Coli
           >gi|396501|emb|CAA50282.1| (X70943) aspartyl-tRNA
           synthetase [Thermus thermophilus]
           Length = 580
           
 Score =  153 bits (383), Expect = 3e-36
 Identities = 106/321 (33%), Positives = 170/321 (52%), Gaps = 30/321 (9%)

Query: 1   MLRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF 60
           M RTHY+  + E   G++V + GWV   +DLGG+ F+ +RDREG+VQ+ A         +
Sbjct: 1   MRRTHYAGSLRETHVGEEVVLEGWVNRRRDLGGLIFLDLRDREGLVQLVA---HPASPAY 57

Query: 61  KLIPKLNSEDVIVVEGIVNFTPK-----AKLGFEIIPEKLEVISKAKT-PLPLDPTGKVK 114
               ++  E V+  +G+V   P+     A    E+    LEV+++AKT P P+D   + +
Sbjct: 58  ATAERVRPEWVVRAKGLVRLRPEPNPRLATGRVEVELSALEVLAEAKTPPFPVDAGWRGE 117

Query: 115 AELDT----RLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATE 170
            E +     RL  R++DLR  R+    ++R  V +A  +F  +EGF+++ TP +  +  E
Sbjct: 118 EEKEASEELRLKYRYLDLRRRRMQENLRLRHRVIKAIWDFLDREGFVQVETPFLTKSTPE 177

Query: 171 GGTELFPLKYFENDAF--LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAW 228
           G  +       E   F  L QSPQL+KQM+M  GLD+ F+I   FR E+    R   +  
Sbjct: 178 GARDFLVPYRHEPGLFYALPQSPQLFKQMLMVAGLDRYFQIARCFRDEDLRADRQ-PDFT 236

Query: 229 SIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEA 288
            +D EM+F+E  E+V++L ERL+ +V    RE    EL +          PFPR++Y+EA
Sbjct: 237 QLDLEMSFVE-VEDVLELNERLMAHVF---REALGVELPL----------PFPRLSYEEA 282

Query: 289 LEILSDLGKEIPWGEDIDTEG 309
           +E       ++ +G ++   G
Sbjct: 283 MERYGSDKPDLRFGLELKEVG 303


>sp|O83618|SYN_TREPA ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRNA LIGASE) (ASNRS)
           >gi|7437574|pir||F71302 asparagine--tRNA ligase (EC
           6.1.1.22) (asnS) - syphilis spirochete
           >gi|3322907|gb|AAC65585.1| (AE001236) asparaginyl-tRNA
           synthetase (asnS) [Treponema pallidum]
           Length = 523
           
 Score =  151 bits (378), Expect = 1e-35
 Identities = 127/516 (24%), Positives = 217/516 (41%), Gaps = 99/516 (19%)

Query: 10  ITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDRE--GIVQVTAP-------------KKK 54
           +T   +G+   V GWV+  ++     FI + D      +QVT P              ++
Sbjct: 12  LTHPPSGQHECVHGWVRSKRETKRAVFISLSDGSCPDTLQVTVPLPECSASLSSGAQAEQ 71

Query: 55  VP---------QEIFKLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPL 105
           +P         + + + + ++ +   I  EG +  +P A    E+    L V+ +A  P 
Sbjct: 72  IPNVRDAVLQGETLAQTLKRVTTGACIRAEGALVPSPGAGQALELRACNLTVLGEA--PA 129

Query: 106 PLDPTGKVKAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKII 165
              P  K     +    +  +  R     +  ++RS++  A   FF +  F  +HTP I 
Sbjct: 130 ETYPLQKKSHSFEFLRAHAHLRARTSTFAACARVRSALAGAVHRFFSERHFQYVHTPIIT 189

Query: 166 ATATEGGTELFPLKYFEN----------------------DAFLAQSPQLYKQMMM---- 199
           A+  EG  ELF +  F+                       D F  ++ +L     +    
Sbjct: 190 ASDCEGAGELFRVTTFDPVRIAREAHAAGAAGNPYALTYADDFFGKAARLTVSGQLQGEA 249

Query: 200 -STGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYVINYV 258
            +  L +++  GP FRAE  NT+RHL+E W ++ E+AF    +  MD+ E  + Y++   
Sbjct: 250 YALALTRIYTFGPTFRAENSNTSRHLSEFWMVEPEIAFARITD-CMDVAEEFLAYLLRAA 308

Query: 259 RENNEKELKILEFELNE-----------------------------------PKKPFPRI 283
            ++  +++  L+    +                                    + P  R+
Sbjct: 309 LKDCAQDIAFLDERAAQHARSARGDTPLAARSTARTPPVRTPGQLTRMLEDVARAPATRL 368

Query: 284 TYDEALEILSDLGKE----IPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFY 339
           TY EA+++L + G+     + WG D+ +E E  L + +          +Y YP E K FY
Sbjct: 369 TYTEAIKLLENSGRSFEFPVRWGCDLQSEHECFLTEEVFHGP----VIVYDYPKEIKAFY 424

Query: 340 IMKYEDKPEVCKAFDLEYRGV-EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEY 398
            MK        ++ DL   G+ EI  G +RE + ++L  +IR  G +P  + +Y     +
Sbjct: 425 -MKLNADGTTVRSMDLLVPGLGEIMGGSEREEQFEVLCARIRASGFDPHDYRWYTDLRRF 483

Query: 399 GMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRR 434
           G  PH GFGLG ERL+  +  +GNIR+VI FPR  R
Sbjct: 484 GTAPHAGFGLGFERLLQYVTGLGNIRDVIPFPRTPR 519


>pir||H82627 aspartyl-tRNA synthetase XF1856 [imported] - Xylella fastidiosa
           (strain 9a5c) >gi|9106945|gb|AAF84662.1|AE004007_1
           (AE004007) aspartyl-tRNA synthetase [Xylella fastidiosa]
           Length = 589
           
 Score =  150 bits (376), Expect = 2e-35
 Identities = 106/298 (35%), Positives = 156/298 (51%), Gaps = 28/298 (9%)

Query: 2   LRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQ---E 58
           +RTH+   I E L G  V +AGW    ++LGG+ FI +RD EGIVQVT   + + Q   E
Sbjct: 1   MRTHFCGLIDETLIGHTVTLAGWTDVARNLGGVCFIDLRDHEGIVQVTVDSRAIDQNNSE 60

Query: 59  IFKLIPKLNSEDVIVVEGIV----NFTPKAKLG-FEIIPEKLEVISKAKTPLPLDPTGKV 113
           +FK+   L+ EDV+ VEG+V        K K G  E+I  K+++++KA  PLP       
Sbjct: 61  LFKVASGLSYEDVLQVEGVVCARHAVNDKIKTGKVEVIATKIKILNKA-APLPFH--AHE 117

Query: 114 KAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGT 173
               D RL  R++DLR P +  + + R  + +A R      GF +I TP +     EG  
Sbjct: 118 NPGEDIRLKYRYLDLRRPEMQRMQRTRIKLVQALRRHLDMHGFQDIETPILTKATPEGAR 177

Query: 174 E-LFPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSID 231
           + L P +    + + L QSPQL+KQ++M  G D+ ++I   FR E     R L E   +D
Sbjct: 178 DFLVPARMHPGEFYALPQSPQLFKQILMVAGFDRYYQIARCFRDEALRADRQL-EFTQLD 236

Query: 232 AEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEAL 289
            E AF+ SE +V D +E +I  V         KE+  +E +       FPR+T+ EA+
Sbjct: 237 MEFAFV-SERDVQDFVEEMIRRVF--------KEVAGIELDTT-----FPRMTWTEAM 280


>pir||H71612 asparagine--tRNA ligase (EC 6.1.1.22) (OO, TP) PFB0525w - malaria
           parasite (Plasmodium falciparum)
           >gi|3845207|gb|AAC71894.1| (AE001400) asparaginyl-tRNA
           synthetase (OO, TP) [Plasmodium falciparum]
           Length = 610
           
 Score =  150 bits (376), Expect = 2e-35
 Identities = 93/265 (35%), Positives = 140/265 (52%), Gaps = 19/265 (7%)

Query: 180 YFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIES 239
           +F   AFL  S QL  + + S+ +  V+  GP FRAE  +T+RHL E W I+ E+AF + 
Sbjct: 345 FFSKQAFLTVSGQLSLENLCSS-MGDVYTFGPTFRAENSHTSRHLAEFWMIEPEIAFADL 403

Query: 240 EEEVMDLLERLILYVINYVRENNEKELKILEFEL---------NEPKKPFPRITYDEALE 290
            +  M+L E  I Y I+YV  NN  ++   E  +         N   + F +ITY  A+E
Sbjct: 404 YDN-MELAEAYIKYCIDYVLNNNFHDIYYFEENVETNLIKRLKNILNEDFAKITYTNAIE 462

Query: 291 ILSDLGK----EIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDK 346
           IL +       ++ WG D+ +E E+ + + + +        +Y YP + K FY+   ED 
Sbjct: 463 ILQNYSDSFEVKVEWGMDLQSEHERFIAEKIFKKP----VIVYNYPKDLKAFYMKLNEDN 518

Query: 347 PEVCKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGF 406
             V     L  +  E+  G QRE   + L + I+EK LN +S+ +Y +  +YG  PH GF
Sbjct: 519 KTVAAMDVLVPKIGEVIGGSQREDNLERLDKMIKEKKLNIDSYWWYRQLRQYGSHPHAGF 578

Query: 407 GLGAERLIMRMLDIGNIREVILFPR 431
           GLG ERLIM +  + NI++ I FPR
Sbjct: 579 GLGFERLIMLVTGVDNIKDTIPFPR 603


>gb|AAD46681.1|AF170909_1 (AF170909) SYNC1 protein [Arabidopsis thaliana]
           >gi|10176772|dbj|BAB09886.1| (AB013392) SYNC1 protein
           [Arabidopsis thaliana]
           Length = 572
           
 Score =  148 bits (370), Expect = 1e-34
 Identities = 91/268 (33%), Positives = 142/268 (52%), Gaps = 22/268 (8%)

Query: 180 YFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIES 239
           +F   AFL  S QL  +   +  L  V+  GP FRAE  +T+RHL E W ++ E+AF + 
Sbjct: 304 FFGRQAFLTVSGQLQVETY-ACALSNVYTFGPTFRAENSHTSRHLAEFWMVEPEIAFADL 362

Query: 240 EEEVMDLLERLILYVINYVRENNEKELKILEFELNE---------PKKPFPRITYDEALE 290
           E++ M+  E  + Y+ N++ E    +++++    +             PF RITY +A+E
Sbjct: 363 EDD-MNCAEAYVKYMCNWLLEKCYADMELMAKNFDSGCIDRLKLVASTPFGRITYTKAIE 421

Query: 291 ILSDL---GKE----IPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKY 343
           +L +    GKE    + WG D+ +E E+ L + + +        +Y YP   K FY+   
Sbjct: 422 LLEEAVAKGKEFDNNVEWGIDLASEHERYLTEVLFQKP----LIVYNYPKGIKAFYMRLN 477

Query: 344 EDKPEVCKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPH 403
           +D+  V     L  +  E+  G QRE R+D++ ++I E GL  E +E+YL    YG   H
Sbjct: 478 DDEKTVAAMDVLVPKVGELIGGSQREERYDVIKKRIEEMGLPIEPYEWYLDLRRYGTVKH 537

Query: 404 GGFGLGAERLIMRMLDIGNIREVILFPR 431
            GFGLG ER+I+    + NIR+VI FPR
Sbjct: 538 CGFGLGFERMILFATGLDNIRDVIPFPR 565


>pir||E83524 aspartyl-tRNA synthetase PA0963 [imported] - Pseudomonas aeruginosa
           (strain PAO1) >gi|9946870|gb|AAG04352.1|AE004530_5
           (AE004530) aspartyl-tRNA synthetase [Pseudomonas
           aeruginosa]
           Length = 591
           
 Score =  148 bits (369), Expect = 2e-34
 Identities = 94/299 (31%), Positives = 161/299 (53%), Gaps = 30/299 (10%)

Query: 1   MLRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF 60
           M+R+HY  ++ E L+G++V + GWV   +D GG+ F+ +RDREG+ QV     +   E F
Sbjct: 1   MMRSHYCGQLNESLDGQEVTLCGWVHRRRDHGGVIFLDVRDREGLAQVVFDPDRA--ETF 58

Query: 61  KLIPKLNSEDVIVVEGIVNFTPK-------AKLGFEIIPEKLEVISKAKT-PLPLDPTGK 112
               ++ SE V+ + G V   P+       A    E++  +LEV+++A+T P PLD    
Sbjct: 59  AKADRVRSEFVVKITGKVRLRPEGARNPNMASGSIEVLGYELEVLNQAETPPFPLDEYSD 118

Query: 113 VKAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGG 172
           V  E  TRL  RF+DLR P + +  K+R+ +  + R +    GF+++ TP +     EG 
Sbjct: 119 VGEE--TRLRYRFIDLRRPEMAAKLKLRARITSSIRRYLDDNGFLDVETPILGRPTPEGA 176

Query: 173 TE-LFPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSI 230
            + L P + +    F L QSPQL+KQ++M  G D+ ++I   FR E+    R   E   I
Sbjct: 177 RDYLVPSRTYPGHFFALPQSPQLFKQLLMVAGFDRYYQIAKCFRDEDLRADRQ-PEFTQI 235

Query: 231 DAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEAL 289
           D E +F++ E +++ + E+++  +            ++L+ E +E    FP + ++EA+
Sbjct: 236 DIETSFLD-ESDIIGITEKMVRQLFK----------EVLDVEFDE----FPHMPFEEAM 279


>dbj|BAB04971.1| (AP001511) aspartyl-tRNA synthetase [Bacillus halodurans]
           Length = 595
           
 Score =  146 bits (366), Expect = 3e-34
 Identities = 95/296 (32%), Positives = 161/296 (54%), Gaps = 26/296 (8%)

Query: 3   RTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKL 62
           RTH+  +++EE   ++V++ GWVQ  +DLG + F+ +RDR G+VQ+      + QE  + 
Sbjct: 4   RTHHCGQLSEEQVNERVQLKGWVQRRRDLGQVIFVDLRDRSGVVQLVF-NSDISQEALET 62

Query: 63  IPKLNSEDVIVVEGIV------NFTPKAKLG-FEIIPEKLEVISKAKTPLPLDPTGKVKA 115
             K+ +E V+ VEG+V          K   G  E+  E+L +++KAK+ LP        A
Sbjct: 63  AEKVRNEYVLDVEGVVLKRDPSTVNDKIATGTIEVHVERLTILNKAKS-LPFQIEANTDA 121

Query: 116 ELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTE- 174
             D RL  R++DLR P +    K+R    +  R+F   + F EI TP +  +  EG  + 
Sbjct: 122 SEDIRLKYRYLDLRRPDMQETMKLRHQTTKLIRDFLDGQEFFEIETPMLTKSTPEGARDY 181

Query: 175 LFPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAE 233
           L P +    + + L QSPQ++KQ++M +G ++ ++I   FR E+    R   E   ID E
Sbjct: 182 LVPSRVHHGEFYALPQSPQIFKQLLMVSGFERYYQIVRCFRDEDLRADRQ-PEFTQIDIE 240

Query: 234 MAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEAL 289
            +F++ +E+++ + E ++  ++        KE+K L+  L     PFPR+TYD+A+
Sbjct: 241 TSFMD-KEDLLTMTENMMAKIM--------KEVKGLDVAL-----PFPRMTYDDAM 282


>sp|P41255|SYK_THETH LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
           >gi|1072959|pir||A55589 lysine--tRNA ligase (EC 6.1.1.6)
           - Thermus aquaticus >gi|486665|emb|CAA50039.1| (X70708)
           lysine--tRNA ligase [Thermus thermophilus]
           Length = 492
           
 Score =  146 bits (365), Expect = 4e-34
 Identities = 132/447 (29%), Positives = 221/447 (48%), Gaps = 52/447 (11%)

Query: 17  KKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVEG 76
           ++V VAG +  ++ +G + F  + D  G +Q+   +   P+  ++L+ KL+  D++ V G
Sbjct: 52  EEVAVAGRLVALRRMGKVTFAHLLDETGRIQLYFQRDLTPK--YELLKKLDVGDILGVRG 109

Query: 77  IVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLR-NPRVMS 135
              FT K     E+  + L+     K+  PL        + + R   R++DL  NP V  
Sbjct: 110 HP-FTTKTG---EVTVKVLDWTPLVKSLHPLPDKWHGLRDKEVRYRQRYLDLIVNPEVRE 165

Query: 136 IFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFEN----DAFLAQSP 191
           +F+ RS + R  R FF  +GF+E+ TP  I   T GG E  P K + N    + +L  S 
Sbjct: 166 VFRRRSEIVRYIRRFFEAKGFLEVETP--ILQPTTGGAEARPFKTYHNALDHEFYLRISL 223

Query: 192 QLYKQMMMSTGLDKVFEIGPIFRAE--EHNTTRHLNEAWSIDAEMAFIESEEEVMDLLER 249
           +LY + ++  G +KVFEIG  FR E  +HN   H  E   ++A  A+ + ++ +  L+E 
Sbjct: 224 ELYLKRLLVGGYEKVFEIGRNFRNEGIDHN---HNPEFTMLEAYWAYADYQD-MAGLVEE 279

Query: 250 LILYVINYVRENNEKEL--KILEFELNEPKKPFPRITYDEALEILS-------DLGKEIP 300
           L+  ++ ++  ++E     ++L F     K PF RI++ EAL+  +       DL +   
Sbjct: 280 LLSGLVLHLFGSHEVPYQGRVLNF-----KPPFRRISFVEALKEKAGLPFDPLDLERLRL 334

Query: 301 WGEDIDTEG---------EKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCK 351
           W +    E          +KL G Y+ E E  +  F++ +P    P    ++ +KP + +
Sbjct: 335 WADAHHPELSQVPNYKLLDKLFGIYV-EPELQDPTFVFDFPLAISPL-AKRHREKPGLVE 392

Query: 352 AFDLEYRGVEISS-----GGQREHRHDILVEQIREKGLN---PESFEFYLRAFEYGMPPH 403
            +DL   G+E++          + R   L +  R K  +   PE  E +L A EYGMPP 
Sbjct: 393 RWDLYAGGMELAPCYSELNDPLDQRERFLEQARRRKEGDEEAPEPDEDFLLALEYGMPPA 452

Query: 404 GGFGLGAERLIMRMLDIGNIREVILFP 430
            G GLG +RL M + D  ++R+V+LFP
Sbjct: 453 AGLGLGIDRLAMLLTDQPSLRDVLLFP 479


>pir||D82910 aspartyl-tRNA synthetase UU286 [imported] - Ureaplasma urealyticum
           >gi|6899259|gb|AAF30695.1|AE002125_6 (AE002125)
           aspartyl-tRNA synthetase [Ureaplasma urealyticum]
           Length = 578
           
 Score =  143 bits (358), Expect = 3e-33
 Identities = 102/300 (34%), Positives = 157/300 (52%), Gaps = 27/300 (9%)

Query: 6   YSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPK 65
           Y   I EE   K V + GWV++V+ +G + F+ ++DR GIVQ+ A K      +F  + +
Sbjct: 4   YCGYIGEEHLEKNVILNGWVKKVRKMGNLVFVDLKDRFGIVQIFATKS---DGVFNELTQ 60

Query: 66  LNSEDVIVVEGIV----NFTPKAKLG-FEIIPEKLEVISKAKTPLPLDPTGKVKAELDTR 120
           L+ EDVI VEG+V    N     K G FEI  +K+ + SKAKTP PL    +  A  + R
Sbjct: 61  LSREDVINVEGLVLLRKNPNNDLKTGRFEIHVKKILIYSKAKTP-PLIIEDETDANEEIR 119

Query: 121 LDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKY 180
              R++DLR    + IF++RS V++A R + Y + FIE  TP +     EG  + +    
Sbjct: 120 FRYRYLDLRRDVNLKIFELRSKVYQAFRNYLYSQDFIETETPILAKPTPEGARDFYVPTR 179

Query: 181 FENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESE 240
                 L QSPQ +KQ++M  G  K F+I   FR E+  + R   E   +D E++F + E
Sbjct: 180 TRKFYALPQSPQTFKQLLMVAGFQKYFQITKCFRDEDLRSDRQ-PEFTQVDIELSFAD-E 237

Query: 241 EEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIP 300
            E+  L+E L+ YV            + +  +L     PF R++Y++A   ++D G + P
Sbjct: 238 IEIQTLIENLLKYVFK----------QTINVDLT---TPFMRMSYEQA---INDYGSDKP 281


>gi|6319872 Asn-tRNA synthetase; Ycr024cp [Saccharomyces cerevisiae]
           >gi|135160|sp|P25345|SYNM_YEAST ASPARAGINYL-TRNA
           SYNTHETASE, MITOCHONDRIAL PRECURSOR (ASPARAGINE--TRNA
           LIGASE) (ASNRS) >gi|83213|pir||S19435 hypothetical
           protein YCR024c - yeast (Saccharomyces cerevisiae)
           >gi|1907168|emb|CAA42316.1| (X59720) YCR024c, len:492
           [Saccharomyces cerevisiae]
           Length = 492
           
 Score =  142 bits (354), Expect = 9e-33
 Identities = 117/461 (25%), Positives = 203/461 (43%), Gaps = 58/461 (12%)

Query: 19  VKVAGWVQEVKDLGGIKFIWIRDREGI--VQVTAPKKKVPQEIFKLIPKLNSEDVIVVEG 76
           + + GW++ ++ L  I F+ ++D   +  +++  P     +  F  I K   + + +   
Sbjct: 34  ISINGWIKSIRLLKRIAFLDLQDGTSVNPLRIVIPLTNTDEVQFLKILK-TGQTLSISNA 92

Query: 77  IVNFTPKAKLGFEII----PEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPR 132
               TP  K  FE+      + ++++       PL    +    L +    ++   R   
Sbjct: 93  TWQSTPNRKQPFELQIKNPVKSIKLVGPVSENYPLQKKYQTLRYLRSLPTLKY---RTAY 149

Query: 133 VMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLK---------YFEN 183
           + +I ++RS V      +F K  F ++  P + +   EG  ELF +          YF  
Sbjct: 150 LSAILRLRSFVEFQFMLYFQKNHFTKVSPPILTSNDCEGAGELFQVSTNTSPTASSYFGK 209

Query: 184 DAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEV 243
             +L  S QL+ +++ +  L + + + P FRAE+ +T RHL+E W ++ EM F+ S  E+
Sbjct: 210 PTYLTVSTQLHLEIL-ALSLSRCWTLSPCFRAEKSDTPRHLSEFWMLEVEMCFVNSVNEL 268

Query: 244 MDLLERLILYVINYVRENNEKEL-----------KILEFELNEP------------KKPF 280
              +E  I ++I    +N ++ L              E  +N+              + +
Sbjct: 269 TSFVETTIKHIIKACIDNQQELLPKQFISSQENNASSELSINQETQQIKTRWEDLINEKW 328

Query: 281 PRITYDEALEILSDLGKEI-------PWGEDIDTEGEKLL-GKYMLENEGAELYFIYRYP 332
             ITY  A+EIL     E+        WG+ + TE EK L G+Y          F+  YP
Sbjct: 329 HNITYTNAIEILKKRHNEVSHFKYEPKWGQPLQTEHEKFLAGEYF-----KSPVFVTDYP 383

Query: 333 SEAKPFYIMKYEDKPEVCKAFDLEYRGV-EISSGGQREHRHDILVEQIREKGLNPE-SFE 390
              KPFY+ +     +    FDL   G+ EI  G  RE  +D L  +++ +G+N     +
Sbjct: 384 RLCKPFYMKQNSTPDDTVGCFDLLVPGMGEIIGGSLREDDYDKLCREMKARGMNRSGELD 443

Query: 391 FYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPR 431
           +Y+   + G  PHGGFGLG ER I  +    NI++ I F R
Sbjct: 444 WYVSLRKEGSAPHGGFGLGFERFISYLYGNHNIKDAIPFYR 484


>gb|AAD55509.1|AC008148_19 (AC008148) Similar to  asparaginyl-tRNA synthetases [Arabidopsis
           thaliana]
           Length = 571
           
 Score =  141 bits (353), Expect = 1e-32
 Identities = 89/269 (33%), Positives = 140/269 (51%), Gaps = 22/269 (8%)

Query: 180 YFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIES 239
           +F   AFL  S QL  +   +  L  V+  GP FRAE  +T+RHL E W ++ E+AF + 
Sbjct: 301 FFGRQAFLTVSGQLQVETY-ACALSSVYTFGPTFRAENSHTSRHLAEFWMVEPEIAFADI 359

Query: 240 EEEVMDLLERLILYVINYVRENNEKELKILEFELNE---------PKKPFPRITYDEALE 290
            ++ M+  E  + Y+  ++ +    ++++++  ++E          K  F R+TY EA+E
Sbjct: 360 HDD-MNCAEAYVKYMCKWLMDKCGDDMELMDKNVDEGCTKRLNMVAKASFKRVTYTEAIE 418

Query: 291 ILSDL---GK-----EIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMK 342
            L      GK     ++ WG D+ +E E+ L +   + +      +Y YP   K FY+  
Sbjct: 419 RLEKAVAQGKVVFDNKVEWGIDLASEHERYLTEVEFDQKPI---IVYNYPKGIKAFYMRL 475

Query: 343 YEDKPEVCKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPP 402
            +D+  V     L  +  E+  G QRE R+D++ ++I E GL  E +E+YL    YG   
Sbjct: 476 NDDEKTVAAMDVLVPKVGELIGGSQREERYDVIKQRIEEMGLPMEPYEWYLDLRRYGTVK 535

Query: 403 HGGFGLGAERLIMRMLDIGNIREVILFPR 431
           H GFGLG ER+I     I NIR+VI FPR
Sbjct: 536 HCGFGLGFERMIQFATGIDNIRDVIPFPR 564


>sp|P73443|SYK_SYNY3 LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
           >gi|7437569|pir||S77380 lysine--tRNA ligase (EC 6.1.1.6)
           - Synechocystis sp. (strain PCC 6803)
           >gi|1652562|dbj|BAA17483.1| (D90906) lysyl-tRNA
           synthetase [Synechocystis sp.]
           Length = 510
           
 Score =  140 bits (350), Expect = 3e-32
 Identities = 135/475 (28%), Positives = 222/475 (46%), Gaps = 62/475 (13%)

Query: 4   THYSSEITEEL----NGK----KVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKV 55
           TH + ++ E      NG+    KV +AG +   + +G + F  ++D  G +Q+   K+++
Sbjct: 39  THQAQDLQETYRDLSNGEEVDLKVAIAGRILARRVMGKLAFFTLQDESGTIQLYLEKQRL 98

Query: 56  PQEI------FKLIPKLNSE-DVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLD 108
            + +      F L+ K+    D++ V G +  T K +L   +  +   V++K+  PLP  
Sbjct: 99  TEHMPELENAFNLLKKITDVGDILGVTGTLKRTEKGELSVYV--QTYAVLTKSLLPLPDK 156

Query: 109 PTGKVKAELDTRLDNRFMDLR-NPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIAT 167
             G    E   R   R++DL  NP V   F+ R+ +  A R +  K+GFIEI TP  +  
Sbjct: 157 WHGLTDTE--KRYRQRYVDLIVNPTVRQTFRRRAQITAAIRRYLDKQGFIEIETP--VLQ 212

Query: 168 ATEGGTELFPLKYFENDA----FLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRH 223
              GG E  P     N      +L  + +L+ + ++  G +KVFE+G IFR  E  +TRH
Sbjct: 213 GESGGAEARPFITHHNTLGMPLYLRIATELHLKRLVVGGFEKVFELGRIFR-NEGVSTRH 271

Query: 224 LNEAWSIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRI 283
             E  SI+   A+++  E +M L E L+      V    +   +  E +L  P K   RI
Sbjct: 272 NPEFTSIEVYQAYVDYNE-MMALTEALVTTAAQAVLGTLKITYQGEEIDLTPPWK---RI 327

Query: 284 TYDEALEI--------LSDL----------GKEIPWGEDIDTEGEKLLGKYMLENEGAEL 325
           T  EA+++         +DL          G  +P  ED  + G  L   +  + EG  +
Sbjct: 328 TMHEAVQLETGIDFSQFTDLETAKQAATKAGIGVP--EDCPSLGHLLNHAFEQKVEGTLM 385

Query: 326 Y--FIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSGGQR-----EHRHDILVEQ 378
              FI  +P E  P     +  KP + + F+L   G E+++         + R  +  + 
Sbjct: 386 QPTFIIDFPVEISPL-AKPHRSKPGLVERFELFVYGRELANSFSELTDPIDQRSRLEAQA 444

Query: 379 IREKGLNPESF---EFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFP 430
            ++   + E+    E +L A EYGMPP GG G+G +RL+M + D  +IR+VI FP
Sbjct: 445 AKKAAGDLEAHSVDEDFLTALEYGMPPTGGLGIGIDRLVMLLTDSPSIRDVIAFP 499


>sp|P56126|SYK_HELPY LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
           >gi|7437568|pir||F64542 lysine--tRNA ligase (EC 6.1.1.6)
           - Helicobacter pylori  (strain 26695)
           >gi|2313270|gb|AAD07251.1| (AE000538) lysyl-tRNA
           synthetase (lysS) [Helicobacter pylori 26695]
           Length = 501
           
 Score =  140 bits (350), Expect = 3e-32
 Identities = 119/443 (26%), Positives = 211/443 (46%), Gaps = 43/443 (9%)

Query: 21  VAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVEGIVNF 80
           + G V+ ++ +G   FI + D   I+QV   + ++  E   L   L   D+++V+G    
Sbjct: 60  IVGRVKLLRLMGKACFIKVEDESTILQVYVSQNELNDEFKSLKKHLEVGDIVLVKGFPFA 119

Query: 81  TPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLR-NPRVMSIFKI 139
           T   +L    +  +  ++SK   PLP    G   ++++ R   R++DL  NP V  +FK 
Sbjct: 120 TKTGELSIHAL--EFHILSKTIVPLPEKFHGL--SDIELRYRQRYLDLIVNPSVKDVFKK 175

Query: 140 RSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFEN----DAFLAQSPQLYK 195
           RS +  + R+FF  EGF+E+ TP +      GG    P   + N    + +L  +P+LY 
Sbjct: 176 RSLIVSSVRKFFEMEGFLEVETPMM--HPIPGGANARPFITYHNALEVERYLRIAPELYL 233

Query: 196 QMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYVI 255
           + ++  G + VFEI   FR E  + + H  E   I+   A+  + E++++L +RL  Y++
Sbjct: 234 KRLIVGGFEAVFEINRNFRNEGMDHS-HNPEFTMIEFYWAY-HTYEDLIELSKRLFDYLL 291

Query: 256 NYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIPWGED----------I 305
             +  +++     +E + N+       I+Y +ALE +  + K+I   ED          I
Sbjct: 292 KTLNLDSKIIYNDMEVDFNQTSV----ISYLDALETIGGISKDILEKEDRLLAYLLEQGI 347

Query: 306 DTEGEKLLGK-------YMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYR 358
             E     GK       + +E++     F+ +YP E  P    + +  P +   F+L   
Sbjct: 348 KVEPNLTYGKLLAEAFDHFVEHQLINPTFVTQYPIEISPL-ARRNDSNPNIADRFELFIA 406

Query: 359 GVEISSGGQREH----RHDILVEQIREKGLNPESFEF----YLRAFEYGMPPHGGFGLGA 410
           G EI++G    +    + +    Q+ EK    E  ++    Y+ A  +GMPP  G G+G 
Sbjct: 407 GKEIANGFSELNDPLDQLERFKNQVAEKEKGDEEAQYMDEDYVWALAHGMPPTAGQGIGI 466

Query: 411 ERLIMRMLDIGNIREVILFPRDR 433
           +RL+M +    +I++VILFP  R
Sbjct: 467 DRLVMLLTGAKSIKDVILFPAMR 489


>pir||D75406 aspartyl-tRNA synthetase, discriminating - Deinococcus radiodurans
           (strain R1) >gi|6459100|gb|AAF10918.1|AE001981_3
           (AE001981) aspartyl-tRNA synthetase, discriminating
           [Deinococcus radiodurans]
           Length = 577
           
 Score =  140 bits (350), Expect = 3e-32
 Identities = 94/297 (31%), Positives = 157/297 (52%), Gaps = 26/297 (8%)

Query: 1   MLRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF 60
           M RT    ++ +    + V + GWV   +DLGG+ F+ +RDR G VQV     +     F
Sbjct: 2   MKRTSLIGQLGQAQQQQTVTLQGWVSRRRDLGGLIFLELRDRSGTVQVQV---EPDSPAF 58

Query: 61  KLIPKLNSEDVIVVEGIVNFTPKAK-----LGFEIIPEKLEVISKAKTPLPLDPTGKVKA 115
               +L +E V  +EG     P+++       FE+I  +++V++ AKTP      G+  A
Sbjct: 59  AEADRLRAEYVAEIEGTFQPRPESQRKGGLADFEVIASRVKVLNAAKTPPFELDKGESVA 118

Query: 116 ELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTE- 174
           E D RL  R++DLR P +     +RS    A  EF   EGFI++ TP +  +  EG  + 
Sbjct: 119 E-DIRLKYRYLDLRRPEMQRALMLRSKAVTAVTEFLDAEGFIQVETPMLTKSTPEGARDF 177

Query: 175 LFPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAE 233
           L P +    + + L QSPQL+KQ++M  G D+ +++   FR E+    R   +   +D E
Sbjct: 178 LVPSRLNPGEFYALPQSPQLFKQLLMIAGFDRYYQLARCFRDEDLRADRQ-PDFTQLDME 236

Query: 234 MAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALE 290
           M+F+E +++V+++ ERL+ +V            ++L+ EL     PFPR++Y +A++
Sbjct: 237 MSFVE-QDDVLEVQERLLAHVFR----------RVLDVEL---PLPFPRMSYFDAMD 279


 Score = 72.6 bits (175), Expect = 8e-12
 Identities = 37/88 (42%), Positives = 51/88 (57%), Gaps = 4/88 (4%)

Query: 351 KAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPES----FEFYLRAFEYGMPPHGGF 406
           +A+DL   G EI  G  R H  ++  +  +  G + E+    F F+L A EYG PPHGG 
Sbjct: 463 QAYDLVMNGFEIGGGSVRIHDPEVQAKMFQAIGFSEEAAREKFGFFLDALEYGTPPHGGI 522

Query: 407 GLGAERLIMRMLDIGNIREVILFPRDRR 434
             G +RL+M M   G+IREVI FP++ R
Sbjct: 523 AWGFDRLLMLMSGAGSIREVIAFPKNNR 550


>pir||D83183 lysyl-tRNA synthetase PA3700 [imported] - Pseudomonas aeruginosa
           (strain PAO1) >gi|9949865|gb|AAG07088.1|AE004789_8
           (AE004789) lysyl-tRNA synthetase [Pseudomonas
           aeruginosa]
           Length = 501
           
 Score =  140 bits (350), Expect = 3e-32
 Identities = 136/465 (29%), Positives = 212/465 (45%), Gaps = 49/465 (10%)

Query: 2   LRTHYSSEITEELNGKK--VKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEI 59
           L+  Y+ +  EEL      VKVAG +     L    FI ++D    +QV   +K +P+E 
Sbjct: 50  LQKQYADKTKEELEAAAIPVKVAGRIM----LNRGSFIVLQDSSERLQVYVNRKTLPEET 105

Query: 60  FKLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDT 119
              I   +  D+I  EG++  + K  L  ++   +L  ++K+  PLP    G    E   
Sbjct: 106 LAEIKTWDLGDIIGAEGVLARSGKGDLYVDMTSVRL--LTKSLRPLPDKHHGLTDTE--Q 161

Query: 120 RLDNRFMDLR-NPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPL 178
           R   R++DL  N      F++RS V    R F  + GF+E+ TP +      GG    P 
Sbjct: 162 RYRQRYVDLMVNEETRHTFRVRSQVIAHIRRFLSERGFLEVETPML--QTIPGGAAAKPF 219

Query: 179 KYFENDA----FLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEM 234
           +   N      FL  +P+LY + ++  G +KVFEI   FR  E  +TRH  E   ++   
Sbjct: 220 ETHHNALDMAMFLRIAPELYLKRLVVGGFEKVFEINRNFR-NEGVSTRHNPEFTMLEFYQ 278

Query: 235 AFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRIT-YDEALEI-- 291
           A+ + E+  MDL E L   +   V    +       F   EP   F R++ +D  L+   
Sbjct: 279 AYADYEDN-MDLTEELFRELAQSVLGTTDVPYGDKVFHFGEP---FVRLSVFDSILKYNP 334

Query: 292 ------LSDLGKEIPWGEDIDTE--GEKLLGKY-------MLENEGAELYFIYRYPSEAK 336
                 L+D+ K     +    +  G + LGK        ++E++  + +FI RYP E  
Sbjct: 335 EITAADLNDVEKARAIAKKAGAKVLGHEGLGKLQVMIFEELVEHKLEQPHFITRYPFEVS 394

Query: 337 PFYIMKYEDKPEVCKAFDLEYRGVEISSG----GQREHRHDILVEQIREKGLNPESFEFY 392
           P      ED P V   F+L   G EI++        E + +  + Q++EK    +    Y
Sbjct: 395 PLARRNDED-PSVTDRFELFIGGREIANAYSELNDAEDQAERFMLQVKEKDAGDDEAMHY 453

Query: 393 ----LRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDR 433
               + A EYGMPP  G G+G +RL+M + +  +IR+VILFP  R
Sbjct: 454 DADFINALEYGMPPTAGEGIGIDRLVMLLTNSPSIRDVILFPHMR 498


>sp|O87821|SYK_RHIME LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
           >gi|3582260|gb|AAC35210.1| (M27221) lysyl-tRNA
           synthetase [Sinorhizobium meliloti]
           Length = 498
           
 Score =  139 bits (348), Expect = 4e-32
 Identities = 131/459 (28%), Positives = 218/459 (46%), Gaps = 59/459 (12%)

Query: 15  NGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVV 74
           +G+ V VAG V   ++ G   F+ + D  G +Q+ + K   P+E   L+P ++  D+I V
Sbjct: 59  SGETVTVAGRVFSSRNSG--MFMDLHDASGKIQIFSHKDTAPEEARALLPMIDLGDIIGV 116

Query: 75  EGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLR-NPRV 133
            G V  T + +L   +  +++ ++ K+  P+P    G   A+++TR   R++D+  N   
Sbjct: 117 TGEVRRTKRGEL--TVNAKEITMLCKSLLPMPEKYHGL--ADIETRYRKRYLDIMVNEES 172

Query: 134 MSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFEN----DAFLAQ 189
              F+ RS +  + R F   EGF+E+ TP +      GG    P K   N    D +L  
Sbjct: 173 KLRFQQRSRIVSSLRRFLEDEGFMEVETPML--QPIYGGATAEPFKTHHNTLKLDMYLRI 230

Query: 190 SPQLYKQMMMSTGL-DKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLE 248
           + +LY   ++ +GL DKVFEI   FR  E  +TRH  E   ++   A+ + E+ VM L+E
Sbjct: 231 AAELYLNAILVSGLTDKVFEINRNFR-NEGVSTRHNPEFTMMECYWAYADYED-VMGLVE 288

Query: 249 RLILYVINYVRENNEKEL--KILEFELNEPKKPFPRITY------------------DEA 288
           R+   +   V    E E   K L F     K PFPR++                   +EA
Sbjct: 289 RMFETLALAVHGKTEFEFGDKQLSF-----KGPFPRVSMPAASRTRPESISLPLKSDEEA 343

Query: 289 LEILSDLGKEIP----WGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYE 344
            +   D G EI     WGE +    E+ +   +++        +  +P +  PF   +  
Sbjct: 344 RQAARDAGVEIEKDATWGEVLAFLFEEKVEATLIQPA-----HVIHFPKDISPF-AKEVP 397

Query: 345 DKPEVCKAFDLEYRGVEISSGGQR-----EHRHDIL--VEQIREKGLNPESF-EFYLRAF 396
            +P + + F+    G EI +         E R  ++  +EQ   +G   ++  E +L A 
Sbjct: 398 GEPRLVERFETYCNGWEIGNAFSELNDPVEQRARMVEQMEQAHARGEKEKTLDEDFLDAM 457

Query: 397 EYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRRR 435
           + GMPP GG G+G +RLIM + +  +IR++ILFP  R++
Sbjct: 458 DQGMPPAGGLGIGVDRLIMLLTNSPSIRDIILFPARRQK 496


>sp|P73851|SYD_SYNY3 ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
           >gi|7437584|pir||S75048 aspartate--tRNA ligase (EC
           6.1.1.12) - Synechocystis sp.  (strain PCC 6803)
           >gi|1652993|dbj|BAA17910.1| (D90910) aspartyl-tRNA
           synthetase [Synechocystis sp.]
           Length = 599
           
 Score =  139 bits (348), Expect = 4e-32
 Identities = 92/300 (30%), Positives = 157/300 (51%), Gaps = 28/300 (9%)

Query: 2   LRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFK 61
           +RTHY  ++     G+ V + GWV   +D GG+ F+ +RDR+GIVQ+ +   + P   + 
Sbjct: 1   MRTHYCGDLRTTHLGETVTLYGWVDRRRDHGGVIFLDLRDRQGIVQIASSPDQTPAS-YP 59

Query: 62  LIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKA---------KTPLPLDPTGK 112
           +   L +E V+ V G+V+  P   L  +I   ++E+ + +         + P  +     
Sbjct: 60  VAEGLRNEYVVQVTGVVSKRPPESLNEKIPTGEIEIYADSIILLNGVNQQLPFVVSSHEA 119

Query: 113 VKAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFY-KEGFIEIHTPKIIATATEG 171
            +   D RL  R++DLR  R+    ++R  V +A R F   +E F+EI TP +  +  EG
Sbjct: 120 EQVREDVRLKYRYLDLRRARLSQNLQLRHQVVKAMRRFLEDQENFLEIETPILTRSTPEG 179

Query: 172 GTE-LFPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWS 229
             + L P +    + + L QSPQL+KQ++M  G+D+ ++I   FR E+    R   E   
Sbjct: 180 ARDYLVPSRVNPGEWYALPQSPQLFKQLLMVAGMDRYYQIARCFRDEDLRADRQ-PEFTQ 238

Query: 230 IDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEAL 289
           +D EM+F+  +EE++DL E LI ++   V+             ++ P +PFPR+TY E++
Sbjct: 239 LDMEMSFM-GQEEILDLNEALICHIFKVVK------------NIDLP-RPFPRLTYQESM 284


 Score = 70.6 bits (170), Expect = 3e-11
 Identities = 36/88 (40%), Positives = 52/88 (58%), Gaps = 4/88 (4%)

Query: 351 KAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPES----FEFYLRAFEYGMPPHGGF 406
           +A+DL   GVEI  G  R ++ ++  +     GL+PE     F F L AFEYG PPHGG 
Sbjct: 478 QAYDLVMNGVEIGGGSLRIYQREVQEKVFATIGLSPEEAHEKFGFLLDAFEYGTPPHGGI 537

Query: 407 GLGAERLIMRMLDIGNIREVILFPRDRR 434
             G +RL+M +    +IR+VI FP+ ++
Sbjct: 538 AYGLDRLVMLLAKEDSIRDVIAFPKTQQ 565


>gb|AAF57921.1| (AE003804) CG6796 gene product [Drosophila melanogaster]
           Length = 460
           
 Score =  139 bits (347), Expect = 6e-32
 Identities = 112/445 (25%), Positives = 202/445 (45%), Gaps = 44/445 (9%)

Query: 16  GKKVKVAGWVQEVKDLGGIKFIWIRD--REGIVQVTAPKKKVPQEIFKLIPKLNSEDVIV 73
           G  + + GW++ V+ L    F+ I D       QV  P+    Q        L    VI 
Sbjct: 24  GDSLAIQGWIKNVRRLKNNTFLDINDGSTSSRFQVVVPRTPENQH-------LAPGSVIA 76

Query: 74  VEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPRV 133
             G +   P     FE+   ++E++++ +       + K K   +   ++  +  R   V
Sbjct: 77  AVGKIQVAPNGS--FELHANQVEMLAEGRLQEGYPFSPKQKHPPEYVREHLHLRSRVDFV 134

Query: 134 MSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLK-------------- 179
            +  ++R    +A  ++   + F++I+TP +     EG  E+F ++              
Sbjct: 135 AAQMRVRHKAQKAIHDYMDDQDFVQINTPLLTTNDCEGAGEVFRVQPDSQDLLKQMNRPN 194

Query: 180 ------YFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAE 233
                 YF++  FL+ S QL+ + M + GL K + + P FRAE   +  HL E +  +AE
Sbjct: 195 IPMEQSYFDSKVFLSVSGQLHLEAM-TYGLGKTYTLSPAFRAENSKSPLHLAEFYMFEAE 253

Query: 234 MAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEP------KKPFPRITYDE 287
           +A +E  E++   +E+++  V N + E + ++L   +   N        + P+  ++YDE
Sbjct: 254 LAHLEEMEKLAQFIEQMLKSVTNRLLETSGEDLSFCQRNSNSNSDLPWLQVPWKIMSYDE 313

Query: 288 ALEILSDLGKEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKP 347
           AL++L +    +     ++    K    +++ + GA + F+  +P++ KPFY+      P
Sbjct: 314 ALQVLQENKDSLKTPISLNEGFSKDQELFLVAHCGAPV-FVVDWPAQQKPFYMKVSRSNP 372

Query: 348 EVCKAFDLEYRGV-EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGF 406
               A DL    V E+  G  RE    IL    +     P+  E+Y+   +YG  P GGF
Sbjct: 373 NRVHALDLLMPAVGELCGGSLRESDPAIL----KSHPHLPKDLEWYVDLRKYGGVPTGGF 428

Query: 407 GLGAERLIMRMLDIGNIREVILFPR 431
           G+G ER +  +  + NIR+VI FPR
Sbjct: 429 GMGFERYLQLVTGVKNIRDVIPFPR 453


>sp|P75068|SYD_MYCPN ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
           >gi|2146065|pir||S73434 aspartate--tRNA ligase (EC
           6.1.1.12) aspS - Mycoplasma pneumoniae (strain ATCC
           29342) >gi|1673765|gb|AAB95756.1| (AE000013)
           aspartyl-tRNA synthetase [Mycoplasma pneumoniae]
           Length = 557
           
 Score =  138 bits (344), Expect = 1e-31
 Identities = 95/303 (31%), Positives = 156/303 (51%), Gaps = 27/303 (8%)

Query: 6   YSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPK 65
           +   +T E   K V +AGWV+ +K LG + F+ + D+   +QVT   K+        +  
Sbjct: 14  FIGNLTSEHLNKTVTIAGWVKRIKKLGELNFVIVGDKTNTIQVTCKNKEQ-------VKY 66

Query: 66  LNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRF 125
           L  ED+++V+G +      +  FEI    + + +K+KTP PL    K  A  + RL  R+
Sbjct: 67  LTREDLVIVKGKLKRLDSVR--FEITNPTITLFAKSKTP-PLIIEDKTDALEEVRLRYRY 123

Query: 126 MDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTE-LFPLKYFEND 184
           +DLR P +     +R  V  A R +  + GFIE+ TP +  +  EG  + L P +  E+ 
Sbjct: 124 LDLRRPVMQKRLALRHKVTLAVRNWLDQMGFIEVETPTLTKSTPEGARDFLVPARIREHS 183

Query: 185 AF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEV 243
            + L QSPQ+YKQ++M  G +K F+I  ++R E+    R   E   ID E+AF  ++E V
Sbjct: 184 FYALPQSPQIYKQLLMVGGTEKYFQIAHVYRDEDSRKDRQ-PEHTQIDLEVAFY-TKEMV 241

Query: 244 MDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIPWGE 303
           MDL++RL + V            ++L  +L   KKPFP + + EA         ++ +G 
Sbjct: 242 MDLIQRLFVDVFR----------QVLNIKL---KKPFPVLKFAEAFNRFGSDKPDLRYGF 288

Query: 304 DID 306
           +++
Sbjct: 289 ELE 291


 Score = 74.9 bits (181), Expect = 2e-12
 Identities = 36/102 (35%), Positives = 64/102 (62%), Gaps = 2/102 (1%)

Query: 333 SEAKPFYIMKYED-KPE-VCKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPESFE 390
           S  +P +++ +E+ K E + + +DL   G E+ SG  R H  ++    ++  G++P+ F 
Sbjct: 427 SNPQPQWLVNFENHKAEALSEQYDLVLNGFELGSGSIRIHDPEVQTRLMQSLGVDPQQFG 486

Query: 391 FYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRD 432
           F + A++YG P H G GLG +RL+M + ++ NIREV+ FP++
Sbjct: 487 FVMEAYQYGAPVHAGMGLGLDRLMMIINNVDNIREVMAFPKN 528


>pir||A42609 lysine--tRNA ligase (EC 6.1.1.6) - Campylobacter jejuni
           >gi|144208|gb|AAA23029.1| (M63448) transfer RNA-Lys
           synthetase [Campylobacter jejuni]
           Length = 501
           
 Score =  137 bits (341), Expect = 3e-31
 Identities = 124/446 (27%), Positives = 214/446 (47%), Gaps = 47/446 (10%)

Query: 21  VAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPK-LNSEDVIVVEGIVN 79
           VAG ++ ++  G   F  I D +  +Q+   K  V +E++ ++ K L   D+++V+G   
Sbjct: 60  VAGRLKLLRIAGKSIFANIEDEDTNLQIYFSKDSVGEELYTILKKNLEVGDIVLVKGFPF 119

Query: 80  FTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDL-RNPRVMSIFK 138
            T   +  F +   ++++ +KA  PLP    G    +++ R   R++D+  N  V   F 
Sbjct: 120 VTKTGE--FSLHASEVKLATKAIVPLPEKYHGLT--DIEQRYRKRYVDMIMNVEVRKDFL 175

Query: 139 IRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFEN----DAFLAQSPQLY 194
           +RS V    R FF  +GF+E+ TP +   A  GG    P   F N    + FL  +P+LY
Sbjct: 176 VRSKVVSLIRHFFENKGFLEVETPMMHPIA--GGANAKPFVTFHNSLGVERFLRIAPELY 233

Query: 195 KQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYV 254
            + ++  G + VFEI   FR E  + T H  E  +I+   A+  + +++MDL E L   +
Sbjct: 234 LKRLIVGGFEAVFEINRCFRNEGMDLT-HNPEFTTIEFYWAY-HNYKDLMDLTEELFALL 291

Query: 255 INYVRENNEKEL--KILEFELNEPKKPFPRITYDEALEILSDLGKEIPWGED-----IDT 307
           ++ +      E   K++ F      KPF RITY +AL     L +++   ++     +  
Sbjct: 292 LDKLNLGKTIEFDGKMINFS-----KPFERITYKDALCKYGGLDRDLIEDKEKILTKLKA 346

Query: 308 EGEKLLGKYMLENEGAELY------------FIYRYPSEAKPFYIMKYEDKPEVCKAFDL 355
           +G +   K  L +  AEL+            F+  +P    P      ED  ++ + F+L
Sbjct: 347 DGFEANEKLELGHLQAELFDNYVEEKLINPTFVIDFPISISPLSRRSDEDS-QIAERFEL 405

Query: 356 EYRGVEISSGGQREH----RHDILVEQIREKGLNPESF----EFYLRAFEYGMPPHGGFG 407
              G E+++G    +    +++  ++QI  K    E      E ++ A  YGMPP  G G
Sbjct: 406 FICGRELANGFNELNDPLDQYERFLKQIEAKNAGDEEACEMDEDFVNALGYGMPPTAGQG 465

Query: 408 LGAERLIMRMLDIGNIREVILFPRDR 433
           +G +RL+M + +  +IR+VILFP  R
Sbjct: 466 IGIDRLVMLLTNKKSIRDVILFPAMR 491


>sp|P41258|SYK_CAMJE LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
           >gi|11271343|pir||G81383 lysine--tRNA ligase (EC
           6.1.1.6) Cj0401 [imported] - Campylobacter jejuni
           (strain NCTC 11168) >gi|6967875|emb|CAB74237.1|
           (AL139075) lysyl-tRNA synthetase [Campylobacter jejuni]
           Length = 501
           
 Score =  137 bits (341), Expect = 3e-31
 Identities = 124/446 (27%), Positives = 214/446 (47%), Gaps = 47/446 (10%)

Query: 21  VAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPK-LNSEDVIVVEGIVN 79
           VAG ++ ++  G   F  I D +  +Q+   K  V +E++ ++ K L   D+++V+G   
Sbjct: 60  VAGRLKLLRIAGKSIFANIEDEDTNLQIYFSKDSVGEELYTILKKNLEVGDIVLVKGFPF 119

Query: 80  FTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDL-RNPRVMSIFK 138
            T   +  F +   ++++ +KA  PLP    G    +++ R   R++D+  N  V   F 
Sbjct: 120 VTKTGE--FSLHASEVKLATKAIVPLPEKYHGLT--DIEQRYRKRYVDMIMNVEVRKDFL 175

Query: 139 IRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFEN----DAFLAQSPQLY 194
           +RS V    R FF  +GF+E+ TP +   A  GG    P   F N    + FL  +P+LY
Sbjct: 176 VRSKVVSLIRHFFENKGFLEVETPMMHPIA--GGANAKPFVTFHNSLGVERFLRIAPELY 233

Query: 195 KQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYV 254
            + ++  G + VFEI   FR E  + T H  E  +I+   A+  + +++MDL E L   +
Sbjct: 234 LKRLIVGGFEAVFEINRCFRNEGMDLT-HNPEFTTIEFYWAY-HNYKDLMDLTEELFALL 291

Query: 255 INYVRENNEKEL--KILEFELNEPKKPFPRITYDEALEILSDLGKEIPWGED-----IDT 307
           ++ +      E   K++ F      KPF RITY +AL     L +++   ++     +  
Sbjct: 292 LDKLNLGKTIEFDGKMINFS-----KPFERITYKDALCKYGGLDRDLIEDKEKILTKLKA 346

Query: 308 EGEKLLGKYMLENEGAELY------------FIYRYPSEAKPFYIMKYEDKPEVCKAFDL 355
           +G +   K  L +  AEL+            F+  +P    P      ED  ++ + F+L
Sbjct: 347 DGFEANEKLELGHLQAELFDNYVEEKLINPTFVIDFPISISPLSRRSDEDS-QIAERFEL 405

Query: 356 EYRGVEISSGGQREH----RHDILVEQIREKGLNPESF----EFYLRAFEYGMPPHGGFG 407
              G E+++G    +    +++  ++QI  K    E      E ++ A  YGMPP  G G
Sbjct: 406 FICGRELANGFNELNDPLDQYERFLKQIEAKNAGDEEACEMDEDFVNALGYGMPPTAGQG 465

Query: 408 LGAERLIMRMLDIGNIREVILFPRDR 433
           +G +RL+M + +  +IR+VILFP  R
Sbjct: 466 IGIDRLVMLLTNKKSIRDVILFPAMR 491


>sp|P57512|SYK_BUCAI LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
           >gi|10039101|dbj|BAB13135.1| (AP001119) lysyl-tRNA
           synthetase [Buchnera sp. APS]
           Length = 506
           
 Score =  137 bits (341), Expect = 3e-31
 Identities = 120/445 (26%), Positives = 210/445 (46%), Gaps = 44/445 (9%)

Query: 18  KVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVEGI 77
           +V +AG + + + +G   F  ++D EG +Q+   +KK+  + ++        D+  + G+
Sbjct: 67  EVSIAGRMVQRRIMGKASFFTLQDIEGKIQIYINEKKISSDFYRF--HFKKWDIGDILGV 124

Query: 78  VNFTPKAKLG-FEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDL-RNPRVMS 135
           +    K K G   I  + + +++K+  PLP    G    E+  R   R++DL  N ++ S
Sbjct: 125 IGTLFKTKTGELSIYCKNVTILNKSLKPLPDKFHGLSNQEI--RYRKRYLDLISNNKLYS 182

Query: 136 IFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDA----FLAQSP 191
           IFK RS++  A R F  +  F+E+ TP +      GG    P   + N+     +L  +P
Sbjct: 183 IFKNRSNIITAIRNFMIENDFLEVETPML--QNIPGGANARPFITYHNEIDSQMYLRIAP 240

Query: 192 QLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLI 251
           +LY + ++  G +++FE+   FR  E  + RH  E   ++A +A+  + E++M+L E L 
Sbjct: 241 ELYLKKLIIGGFERIFELNRNFR-NEGVSARHNPEFTMMEAYIAY-SNYEDMMELTENLF 298

Query: 252 LYVINYVRENNEKELKILEFELNEPKKPFPRITY-DEALEI--------LSDLGKEIPWG 302
             +  ++ ++N+       F+ ++P   F R+T  D  LE         L D  K   + 
Sbjct: 299 KSITKFLFQDNKIIFNNNNFDFSQP---FRRLTMTDSILEFNSTITSSDLKDFYKIREFA 355

Query: 303 EDIDTEGEKLLGKYMLENEGAELY---------FIYRYPSEAKPFYIMKYEDKPEVCKAF 353
           + I  + EK  G   +E E  E           FI +YP E  P    + +    +   F
Sbjct: 356 KSIGIKVEKKWGCGQIETEIFEKTVEKKLIQPTFITQYPVEVSPL-ARRNDINLNITDRF 414

Query: 354 DLEYRGVEISSGGQR----EHRHDILVEQIREKGLNPESFEFY----LRAFEYGMPPHGG 405
           +L   G EI +G       E +    + QI++         FY    + A +YG+PP  G
Sbjct: 415 ELFIGGYEIGNGFSELNDVEDQKTRFLNQIQKSNKEDNKNLFYDKEYIEALKYGLPPTSG 474

Query: 406 FGLGAERLIMRMLDIGNIREVILFP 430
            G+G +RLIM + +  +IR+VILFP
Sbjct: 475 LGIGIDRLIMILTNQISIRDVILFP 499


>dbj|BAB15655.1| (AK027094) unnamed protein product [Homo sapiens]
           Length = 250
           
 Score =  137 bits (341), Expect = 3e-31
 Identities = 90/251 (35%), Positives = 133/251 (52%), Gaps = 26/251 (10%)

Query: 199 MSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYVINYV 258
           MS    +VF  GP FRAE   + RHL E + I+AE++F++S +++M ++E L       V
Sbjct: 1   MSGAFTQVFTFGPTFRAENSQSRRHLAEFYMIEAEISFVDSLQDLMQVIEELFKATTMMV 60

Query: 259 RENNEKELKI------------LEFELNEPKKPFPRITYDEALEILSDLGKEIP----WG 302
                +++++            LE  L   K  F  I+Y EA+EIL    +       WG
Sbjct: 61  LSKCPEDVELCHKFIAPGQKDRLEHML---KNNFLIISYTEAVEILKQASQNFTFTPEWG 117

Query: 303 EDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPE-VCKAFDLEYRGV- 360
            D+ TE EK    Y++++ G    F+  YP   KPFY+   ED P+    A DL   GV 
Sbjct: 118 ADLRTEHEK----YLVKHCGNIPVFVINYPLTLKPFYMRDNEDGPQHTVAAVDLLVPGVG 173

Query: 361 EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDI 420
           E+  GG RE R+  L E++   GL  E +++YL    +G  PHGGFG+G ER +  +L +
Sbjct: 174 ELFGGGLREERYHFLEERLARSGLT-EVYQWYLDLRRFGSVPHGGFGIGFERYLQCILGV 232

Query: 421 GNIREVILFPR 431
            NI++VI FPR
Sbjct: 233 DNIKDVIPFPR 243


>pir||F82234 aspartyl-tRNA synthetase VC1166 [imported] - Vibrio cholerae (group
           O1 strain N16961) >gi|9655641|gb|AAF94325.1| (AE004196)
           aspartyl-tRNA synthetase [Vibrio cholerae]
           Length = 591
           
 Score =  136 bits (340), Expect = 4e-31
 Identities = 96/297 (32%), Positives = 154/297 (51%), Gaps = 30/297 (10%)

Query: 2   LRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFK 61
           +R+HY   + + L G+ V++ GWV   +DLGG+ FI +RDREGIVQV         ++F 
Sbjct: 1   MRSHYCGHLNKSLVGQTVELCGWVNRRRDLGGLIFIDMRDREGIVQVVVDPDMA--DVFA 58

Query: 62  LIPKLNSEDVIVVEGIVNFTPKAKLG-------FEIIPEKLEVISKAKTPLPLDPTGKVK 114
           +  +L SE  I + G V   P++++         E++   LE+I+++   LPLD   K  
Sbjct: 59  VANQLRSEFCIKLTGEVRARPESQVNKEMATGEVELLARSLEIINRSDV-LPLDFNQKNS 117

Query: 115 AELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTE 174
            E   RL  R++DLR P +    K+R+      R F    GF++I TP +     EG  +
Sbjct: 118 EE--QRLKYRYLDLRRPEMSDRIKLRAKASSFVRRFLDTHGFLDIETPVLTKATPEGARD 175

Query: 175 -LFPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDA 232
            L P +  +   + L QSPQL+KQ++M +G D+ ++I   FR E+    R   E   ID 
Sbjct: 176 YLVPSRVHKGSFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQ-PEFTQIDI 234

Query: 233 EMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEAL 289
           E +F+ + E+V  + E++I           E  L++L  +L +    FP + Y EA+
Sbjct: 235 ETSFM-TAEQVRAVTEKMI----------REMWLELLNVDLGD----FPIMPYSEAM 276


>sp|P14825|SYK2_ECOLI LYSYL-TRNA SYNTHETASE, HEAT INDUCIBLE (LYSINE--TRNA LIGASE) (LYSRS)
           >gi|1361209|pir||S56358 lysine--tRNA ligase (EC 6.1.1.6)
           - Escherichia coli >gi|7428467|pir||SYECKU lysine--tRNA
           ligase (EC 6.1.1.6), thermoinducible - Escherichia coli
           >gi|398703|emb|CAA34542.1| (X16542) lysyl-tRNA
           synthetase (AA 1-505) [Escherichia coli]
           >gi|536974|gb|AAA97029.1| (U14003) lysyl-tRNA synthetase
           [Escherichia coli] >gi|1790571|gb|AAC77090.1| (AE000485)
           lysine tRNA synthetase, inducible; heat shock protein
           [Escherichia coli K12]
           Length = 505
           
 Score =  136 bits (338), Expect = 6e-31
 Identities = 128/473 (27%), Positives = 209/473 (44%), Gaps = 54/473 (11%)

Query: 3   RTHYSSEITEELNGK----------KVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPK 52
           R H S ++ EE + K          +V VAG +   + +G   F+ ++D  G +Q+   +
Sbjct: 42  RDHTSDQLHEEFDAKDNQELESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVAR 101

Query: 53  KKVPQEIFK-LIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTG 111
             +P+ ++     K +  D+I   G +  T   +L       +L +++KA  PLP    G
Sbjct: 102 DSLPEGVYNDQFKKWDLGDIIGARGTLFKTQTGELSIHCT--ELRLLTKALRPLPDKFHG 159

Query: 112 KVKAELDTRLDNRFMDL-RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATE 170
               E+  R   R++DL  N +    F +RS +  A R+F    GF+E+ TP +      
Sbjct: 160 LQDQEV--RYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMM--QVIP 215

Query: 171 GGTELFPLKYFEN----DAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNE 226
           GG    P     N    D +L  +P+LY + ++  G ++VFEI   FR  E  + RH  E
Sbjct: 216 GGASARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFR-NEGISVRHNPE 274

Query: 227 AWSIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYD 286
              ++  MA+ +  + +++L E L   +   V    +       F+     KPF ++T  
Sbjct: 275 FTMMELYMAYADYHD-LIELTESLFRTLAQEVLGTTKVTYGEHVFDFG---KPFEKLTMR 330

Query: 287 EALEILS-----------DLGKEIPWGEDIDTEGEKLLGKYMLE--NEGAELY-----FI 328
           EA++              D  K +     I  E    LG+ + E  +E AE +     FI
Sbjct: 331 EAIKKYRPETDMADLDNFDAAKALAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQPTFI 390

Query: 329 YRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSG----GQREHRHDILVEQIREKGL 384
             YP+E  P    + +  PE+   F+    G EI +G       E + +   EQ+  K  
Sbjct: 391 TEYPAEVSPL-ARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAA 449

Query: 385 NPESFEFY----LRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDR 433
             +   FY    + A EYG+PP  G G+G +R+IM   +   IR+VILFP  R
Sbjct: 450 GDDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMIMLFTNSHTIRDVILFPAMR 502


>pdb|1E1O|A Chain A, Lysyl-Trna Synthetase (Lysu) Hexagonal For, Complexed With
           L >gi|9954997|pdb|1E1T|A Chain A, Lysyl-Trna Synthetase
           (Lysu) Hexagonal Form Complexed With T Lysyl_adenylate
           Intermediate >gi|9954998|pdb|1E22|A Chain A, Lysyl-Trna
           Synthetase (Lysu) Hexagonal Form Complexed With Lysine
           And The Non-Hydrolysable Atp Analogue Amp-Pcp
           >gi|9954999|pdb|1E24|A Chain A, Lysyl-Trna Synthetase
           (Lysu) Hexagonal Form Complexed With Lysine And Atp And
           Mn2+ >gi|1311301|pdb|1LYL|A Chain A, Lysyl-Trna
           Synthetase (Lysu) (E.C.6.1.1.6) Complexed With Lysine
           >gi|1311305|pdb|1LYL|C Chain C, Lysyl-Trna Synthetase
           (Lysu) (E.C.6.1.1.6) Complexed With Lysine
           >gi|1311303|pdb|1LYL|B Chain B, Lysyl-Trna Synthetase
           (Lysu) (E.C.6.1.1.6) Complexed With Lysine
           Length = 504
           
 Score =  136 bits (338), Expect = 6e-31
 Identities = 128/473 (27%), Positives = 209/473 (44%), Gaps = 54/473 (11%)

Query: 3   RTHYSSEITEELNGK----------KVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPK 52
           R H S ++ EE + K          +V VAG +   + +G   F+ ++D  G +Q+   +
Sbjct: 41  RDHTSDQLHEEFDAKDNQELESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVAR 100

Query: 53  KKVPQEIFK-LIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTG 111
             +P+ ++     K +  D+I   G +  T   +L       +L +++KA  PLP    G
Sbjct: 101 DSLPEGVYNDQFKKWDLGDIIGARGTLFKTQTGELSIHCT--ELRLLTKALRPLPDKFHG 158

Query: 112 KVKAELDTRLDNRFMDL-RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATE 170
               E+  R   R++DL  N +    F +RS +  A R+F    GF+E+ TP +      
Sbjct: 159 LQDQEV--RYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMM--QVIP 214

Query: 171 GGTELFPLKYFEN----DAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNE 226
           GG    P     N    D +L  +P+LY + ++  G ++VFEI   FR  E  + RH  E
Sbjct: 215 GGASARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFR-NEGISVRHNPE 273

Query: 227 AWSIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYD 286
              ++  MA+ +  + +++L E L   +   V    +       F+     KPF ++T  
Sbjct: 274 FTMMELYMAYADYHD-LIELTESLFRTLAQEVLGTTKVTYGEHVFDFG---KPFEKLTMR 329

Query: 287 EALEILS-----------DLGKEIPWGEDIDTEGEKLLGKYMLE--NEGAELY-----FI 328
           EA++              D  K +     I  E    LG+ + E  +E AE +     FI
Sbjct: 330 EAIKKYRPETDMADLDNFDAAKALAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQPTFI 389

Query: 329 YRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSG----GQREHRHDILVEQIREKGL 384
             YP+E  P    + +  PE+   F+    G EI +G       E + +   EQ+  K  
Sbjct: 390 TEYPAEVSPL-ARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAA 448

Query: 385 NPESFEFY----LRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDR 433
             +   FY    + A EYG+PP  G G+G +R+IM   +   IR+VILFP  R
Sbjct: 449 GDDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMIMLFTNSHTIRDVILFPAMR 501


>sp|O67258|SYK_AQUAE LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
           >gi|7437570|pir||G70403 lysine--tRNA ligase (EC 6.1.1.6)
           - Aquifex aeolicus >gi|2983651|gb|AAC07218.1| (AE000728)
           lysyl-tRNA synthetase [Aquifex aeolicus]
           Length = 597
           
 Score =  134 bits (334), Expect = 2e-30
 Identities = 119/447 (26%), Positives = 215/447 (47%), Gaps = 40/447 (8%)

Query: 15  NGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPK-LNSEDVIV 73
           N + V +AG +  ++ +G   F  I+D  G +Q+   K  + +E  K     ++  D++ 
Sbjct: 150 NFRPVSLAGRLVSMRSMGKAIFGHIQDLTGKIQIYLKKDVIGEEKLKFFNDYIDVGDIVG 209

Query: 74  VEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDL-RNPR 132
           V G +  T   +L  E+  E+ ++++K+  PLP    G    +++ R   R++DL  NP 
Sbjct: 210 VRGKLFRTNTGELTVEV--EEYQLLAKSLHPLPEKWHGL--KDVEVRYRQRYLDLIANPE 265

Query: 133 VMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPL--KYFENDAFLAQS 190
              IF +R+ +    R+FF   GFIE+ TP +   A+      F     + E + +L  +
Sbjct: 266 ARRIFMLRTKLITEMRKFFEMHGFIEVETPILQPIASGANARPFVTYHNFLETELYLRIA 325

Query: 191 PQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERL 250
           P+LY + ++  G  +V+EIG  FR E  + T H  E   ++   A+ +  + ++   E +
Sbjct: 326 PELYLKRLIVGGFPRVYEIGKNFRNESVDRT-HNPEFTMVEFYAAYWDYHD-LIKFTEDM 383

Query: 251 ILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEAL---------------EILSDL 295
            +Y++   +     ++K  E+EL+    PF ++ Y + L               E L  L
Sbjct: 384 FVYLLE--KTLGTLKVKYGEWELDF-SPPFKKVRYFDLLKEKTGKDKDFFLKDLEGLRKL 440

Query: 296 GKEIPWGEDIDTEGEKLLGKY---MLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKA 352
            KE+   +       KLL K    + E +  +  F+  +P    P      ED P++ + 
Sbjct: 441 AKELEIPDVERMTHAKLLDKVFEKVAEEDLIQPTFVIDFPKILSPLAKTHRED-PDLVER 499

Query: 353 FDLEYRGVEISSGGQREH----RHDILVEQIREKGLNPESF----EFYLRAFEYGMPPHG 404
           F+L     E+++     +    + +  +EQ++EK +  E      E ++RA EYGMPP  
Sbjct: 500 FELIIARYEVANAYTELNDPFDQKERFLEQLKEKQMGDEEAMDMDEDFIRALEYGMPPTA 559

Query: 405 GFGLGAERLIMRMLDIGNIREVILFPR 431
           G G+G +RL+M + +  +IREVILFP+
Sbjct: 560 GEGIGIDRLVMILANTDSIREVILFPQ 586


>sp|P47282|SYD_MYCGE ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
           >gi|1361448|pir||I64203 aspartate--tRNA ligase (EC
           6.1.1.12) - Mycoplasma genitalium
           >gi|3844646|gb|AAC71252.1| (U39683) aspartyl-tRNA
           synthetase (aspS) [Mycoplasma genitalium]
           Length = 550
           
 Score =  134 bits (333), Expect = 3e-30
 Identities = 91/297 (30%), Positives = 152/297 (50%), Gaps = 28/297 (9%)

Query: 11  TEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSED 70
           TE+LN K + + GW++ +K LG I FI + D+ G +QVT   K       + I +L  ED
Sbjct: 14  TEQLN-KTIVIIGWIKRIKKLGEINFIIVGDKSGTIQVTCKDK-------EQIQQLTRED 65

Query: 71  VIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRN 130
           +++V+  +      +  FE+I   +++ SK+KTP PL    +  A  + RL  R++DLR 
Sbjct: 66  IVIVKAKLQRLDSVR--FELINPTIKLFSKSKTP-PLIIEDETDALEEVRLKYRYLDLRR 122

Query: 131 PRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAF--LA 188
             +     +R     A R +F ++GFIEI TP +  +  EG  +         D F  L 
Sbjct: 123 RLMQKRLLLRHQFILAIRNWFNQQGFIEIETPTLSKSTPEGAQDFLVPARIRKDCFYALV 182

Query: 189 QSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLE 248
           QSPQ+YKQ++M  G++K F+I  ++R E+    R   E   ID E++F  +++ +M+L+E
Sbjct: 183 QSPQIYKQLLMIAGVEKYFQIARVYRDEDSRKDRQ-PEHTQIDFEISFC-NQKMIMNLVE 240

Query: 249 RLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIPWGEDI 305
           +L   V           L + + ++   KK FP   + E  E       ++ +G +I
Sbjct: 241 KLFFSVF----------LDVFQIKI---KKTFPVFKFSELFERFGSDKPDLRYGFEI 284


 Score = 69.5 bits (167), Expect = 7e-11
 Identities = 38/102 (37%), Positives = 55/102 (53%), Gaps = 2/102 (1%)

Query: 333 SEAKPFYIMKYEDKPE--VCKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPESFE 390
           S+ K  +I  +E      + + FDL   G EI SG  R +   +    +    ++P  F 
Sbjct: 421 SKPKQEWIDNFESNKNEALSEQFDLVLNGFEIGSGSIRINDPIVQKRLMNSLNIDPNKFA 480

Query: 391 FYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRD 432
           F L A++YG P HGG GLG +RL+M +    NIREVI FP++
Sbjct: 481 FLLEAYQYGAPVHGGMGLGIDRLMMILNQTDNIREVIAFPKN 522


>sp|Q9ZMP8|SYK_HELPJ LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
           >gi|7437567|pir||F71965 lysine--tRNA ligase (EC 6.1.1.6)
           - Helicobacter pylori  (strain J99)
           >gi|4154685|gb|AAD05751.1| (AE001455) LYSYL-TRNA
           SYNTHETASE [Helicobacter pylori J99]
           Length = 501
           
 Score =  134 bits (333), Expect = 3e-30
 Identities = 119/443 (26%), Positives = 207/443 (45%), Gaps = 43/443 (9%)

Query: 21  VAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVEGIVNF 80
           V G V+ ++ +G   FI I D   I+Q    + ++  E   L   L   D+++V+G    
Sbjct: 60  VVGRVKLLRLMGKACFIKIEDESAILQAYVSQNELNDEFKSLKKHLEVGDIVLVKGFPFA 119

Query: 81  TPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLR-NPRVMSIFKI 139
           T   +L    +  +  ++SK   PLP    G   ++++ R   R++DL  NP V  +FK 
Sbjct: 120 TKTGELSIHAL--EFHILSKTIVPLPEKFHGL--SDIELRYRQRYLDLIVNPGVKDVFKK 175

Query: 140 RSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFEN----DAFLAQSPQLYK 195
           RS +  + R+FF  EGF+E+ TP +      GG    P   + N    + +L  +P+LY 
Sbjct: 176 RSLIVSSVRKFFEMEGFLEVETPMM--HPIPGGANARPFITYHNALEIERYLRIAPELYL 233

Query: 196 QMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYVI 255
           + ++  G + VFEI   FR E  + + H  E   I+   A+  + E++++L +RL  Y++
Sbjct: 234 KRLIVGGFEAVFEINRNFRNEGMDHS-HNPEFTMIEFYWAY-HTYEDLIELSKRLFDYLL 291

Query: 256 NYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIPWGED----------I 305
             +  +++     +E + N+       I+Y +ALE +  + K I   ED          I
Sbjct: 292 KTLNLDSKIIYNDMEVDFNQTSV----ISYLDALETIGGISKGILEKEDRLLAYLLEQGI 347

Query: 306 DTEGEKLLGK-------YMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYR 358
             E     GK       + +E++     F+  YP E  P    + +  P +   F+L   
Sbjct: 348 KVEPNLTHGKLLAEAFDHFVEHKLINPTFVTEYPIEISPL-ARRNDSNPNIADRFELFIA 406

Query: 359 GVEISSGGQREH----RHDILVEQIREKGLNPESFEF----YLRAFEYGMPPHGGFGLGA 410
           G EI++G    +    + +    Q+ EK    E  ++    Y+ A  + MPP  G G+G 
Sbjct: 407 GKEIANGFSELNDPLDQLERFKNQVAEKEKGDEEAQYMDEDYVWALAHEMPPTAGQGIGI 466

Query: 411 ERLIMRMLDIGNIREVILFPRDR 433
           +RL+M +    +I++VILFP  R
Sbjct: 467 DRLVMLLTGAKSIKDVILFPAMR 489


>pir||G81412 aspartate--tRNA ligase (EC 6.1.1.12) Cj0640c [imported] -
           Campylobacter jejuni (strain NCTC 11168)
           >gi|6968107|emb|CAB75276.1| (AL139075) aspartyl-tRNA
           synthetase [Campylobacter jejuni]
           Length = 583
           
 Score =  134 bits (333), Expect = 3e-30
 Identities = 91/298 (30%), Positives = 150/298 (49%), Gaps = 28/298 (9%)

Query: 2   LRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFK 61
           +R+HY++++     G+ VK+ GWV   +D GG+ FI +RDR GI+Q+        +E  +
Sbjct: 1   MRSHYNTDLGISHVGQSVKLCGWVNSYRDHGGVIFIDLRDRSGIIQLVCDPND-SKEAHE 59

Query: 62  LIPKLNSEDVIVVEGIVN------FTPKAKLG-FEIIPEKLEVISKAKTPLPLDPTGKVK 114
           +     +E V++ EG +         PK K G  E++  KL + +++  P        V 
Sbjct: 60  IASNARNEFVLITEGTIRPRGEGLVNPKLKTGEIEVVVSKLTIENESAVPPFAIADESVN 119

Query: 115 AELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTE 174
            EL  RL  RF+DLRNP++   F +RS    A R      GF+E+ TP +     EG  +
Sbjct: 120 EEL--RLKYRFLDLRNPKLYENFALRSKACIAARNSLANMGFLEVETPILTKATPEGARD 177

Query: 175 -LFPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDA 232
            L P +  + + + L QSPQL+KQ++M +G D+ F+I   FR E+    R   E   ID 
Sbjct: 178 YLVPSRVHQGEFYALPQSPQLFKQLLMCSGFDRYFQIAKCFRDEDLRADRQ-PEFTQIDV 236

Query: 233 EMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALE 290
           EM+F E +++V+ + E  +  +     +              E + PF ++ Y +A+E
Sbjct: 237 EMSFCE-QKDVIKVAETFLKDIFKACGK--------------EIQTPFRQMQYKDAME 279


>gb|AAK40448.1| Lysyl-tRNA synthetase (lysS) [Sulfolobus solfataricus]
           Length = 494
           
 Score =  132 bits (330), Expect = 6e-30
 Identities = 124/449 (27%), Positives = 215/449 (47%), Gaps = 58/449 (12%)

Query: 19  VKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVEGIV 78
           +  AG V  ++  G   F+ I D    +Q+     ++ ++  K    +   D+I V+G +
Sbjct: 56  ISTAGRVANIRRHGKASFVDIFDEGEKLQLYMRVDELKEKYDKFFIYVGRGDIIGVKGDL 115

Query: 79  NFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMD-LRNPRVMSIF 137
            +T K +L   ++ +  +++SKA     ++P    K   + R  +R++D L N       
Sbjct: 116 FYTMKGELS--LLVKDYQLLSKAL----IEPPDWSKLSPEFRYAHRYVDFLYNDNARKAM 169

Query: 138 KIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLK----YFENDAFLAQSPQL 193
           +IR ++ R  REF Y +GFIE+ TP  I     GG    P K    Y   D +L  + +L
Sbjct: 170 EIRYTIIREIREFLYSKGFIEVETP--IVQPVYGGALAKPFKTHVNYLNEDWYLRIALEL 227

Query: 194 YKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILY 253
           Y +  +  G +KVFEIG +FR E+ + T H  E   ++   A+ +  + +M+L E L+  
Sbjct: 228 YLKRYIIGGFNKVFEIGKVFRNEDIDVT-HNPEFTLLELYWAYADYND-IMNLTEDLLKS 285

Query: 254 VINYVRENNEKELKILEFELNEPKKPFPRIT-YDEALEILSDLGKEIPWGEDIDTEGEKL 312
           V+  V   N  ++   ++E++  + PF RI+ YD   EIL   GK++      D E ++L
Sbjct: 286 VVKKV--TNSTKIVYGKYEIDF-EGPFKRISMYDSLSEIL---GKDVE--SMSDNELKEL 337

Query: 313 LGKYMLENEGAELY---------------------FIYRYPSEAKPFYIMKYEDKPEVCK 351
           + KY L   G +                       FI  YP E  P     + +KP + +
Sbjct: 338 MKKYNLTPRGNQYVRGLMIEKLFDKLVTPTLTNPTFITDYPIETTPL-CKPHRNKPGLVE 396

Query: 352 AFDLEYRGVEISSGGQREHRHDILVEQI----------REKGLNPESFEFYLRAFEYGMP 401
            F++   G+E+++    E    IL +++           ++  +P   +F +RA  YGMP
Sbjct: 397 RFEMFIAGMEVANA-YTELNDPILQDKLFREEQEMFRRGDEEAHPYDKDF-VRALSYGMP 454

Query: 402 PHGGFGLGAERLIMRMLDIGNIREVILFP 430
           P GG G+G +R++M + +  +I+EVI FP
Sbjct: 455 PTGGLGIGIDRIVMLVTNNYSIKEVIPFP 483


>sp|P95970|SYK_SULSO LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
           >gi|7437603|pir||S75398 lysine--tRNA ligase (EC 6.1.1.6)
           - Sulfolobus solfataricus >gi|1707804|emb|CAA69561.1|
           (Y08257) lysyl tRNA synthetase [Sulfolobus solfataricus]
           Length = 494
           
 Score =  132 bits (330), Expect = 6e-30
 Identities = 124/449 (27%), Positives = 215/449 (47%), Gaps = 58/449 (12%)

Query: 19  VKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVEGIV 78
           +  AG V  ++  G   F+ I D    +Q+     ++ ++  K    +   D+I V+G +
Sbjct: 56  ISTAGRVANIRRHGKASFVDIFDEGEKLQLYMRVDELKEKYDKFFIYVGRGDIIGVKGDL 115

Query: 79  NFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMD-LRNPRVMSIF 137
            +T K +L   ++ +  +++SKA     ++P    K   + R  +R++D L N       
Sbjct: 116 FYTMKGELS--LLVKDYQLLSKAL----IEPPDWSKLSPEFRYAHRYVDFLYNDNARKAM 169

Query: 138 KIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLK----YFENDAFLAQSPQL 193
           +IR ++ R  REF Y +GFIE+ TP  I     GG    P K    Y   D +L  + +L
Sbjct: 170 EIRYTIIREIREFLYSKGFIEVETP--IVQPVYGGALAKPFKTHVNYLNEDWYLRIALEL 227

Query: 194 YKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILY 253
           Y +  +  G +KVFEIG +FR E+ + T H  E   ++   A+ +  + +M+L E L+  
Sbjct: 228 YLKRYIIGGFNKVFEIGKVFRNEDIDVT-HNPEFTLLELYWAYADYND-IMNLTEDLLKS 285

Query: 254 VINYVRENNEKELKILEFELNEPKKPFPRIT-YDEALEILSDLGKEIPWGEDIDTEGEKL 312
           V+  V   N  ++   ++E++  + PF RI+ YD   EIL   GK++      D E ++L
Sbjct: 286 VVKKV--TNSTKIVYGKYEIDF-EGPFKRISMYDSLSEIL---GKDVE--SMSDNELKEL 337

Query: 313 LGKYMLENEGAELY---------------------FIYRYPSEAKPFYIMKYEDKPEVCK 351
           + KY L   G +                       FI  YP E  P     + +KP + +
Sbjct: 338 MKKYNLTPRGNQYVRGLMIEKLFDKLVTPTLTNPTFITDYPIETTPL-CKPHRNKPGLVE 396

Query: 352 AFDLEYRGVEISSGGQREHRHDILVEQI----------REKGLNPESFEFYLRAFEYGMP 401
            F++   G+E+++    E    IL +++           ++  +P   +F +RA  YGMP
Sbjct: 397 RFEMFIAGMEVANA-YTELNDPILQDKLFREEQEMFRRGDEEAHPYDKDF-VRALSYGMP 454

Query: 402 PHGGFGLGAERLIMRMLDIGNIREVILFP 430
           P GG G+G +R++M + +  +I+EVI FP
Sbjct: 455 PTGGLGIGIDRIVMLVTNNYSIKEVIPFP 483


>sp|P43825|SYK_HAEIN LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
           >gi|1074993|pir||D64110 lysine--tRNA ligase (EC 6.1.1.6)
           - Haemophilus influenzae  (strain Rd KW20)
           >gi|1574141|gb|AAC22865.1| (U32800) lysyl-tRNA
           synthetase (lysU) [Haemophilus influenzae Rd]
           Length = 502
           
 Score =  132 bits (329), Expect = 7e-30
 Identities = 130/470 (27%), Positives = 216/470 (45%), Gaps = 48/470 (10%)

Query: 2   LRTHYSSEITEELNGK--KVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEI 59
           L   Y +E  E L  K  +V+VAG +   + +G   FI I+D  G +Q+   +  +P+ +
Sbjct: 45  LHNQYDAEDGEILKEKGIEVQVAGRIMTRRAMGKATFITIQDMSGKIQLYVARDNLPEGV 104

Query: 60  FKL-IPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELD 118
           +K  +   +  D++ ++G +  T   +L   +   ++++++KA  PLP    G    E+ 
Sbjct: 105 YKDDVGTWDLGDIVGIKGTLFKTKTDEL--TVKTTEVQLLTKALRPLPDKFHGLTDQEV- 161

Query: 119 TRLDNRFMDL-RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFP 177
            R   R++DL  N      F IRS V    RE+F  +GF+E+ TP +      GG    P
Sbjct: 162 -RYRQRYLDLISNEESRRTFIIRSKVVAGIREYFISKGFMEVETPML--QVIPGGASARP 218

Query: 178 LKYFEN----DAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAE 233
                N    D +L  +P+LY + ++  G ++VFE+   FR  E  + RH  E   ++  
Sbjct: 219 FVTHHNALDVDMYLRIAPELYLKRLVVGGFERVFELNRNFR-NEGVSVRHNPEFTMLEYY 277

Query: 234 MAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEAL---- 289
            A+ +  + +MD  E L+  +   +      +   LEF+     KPF RIT  +A     
Sbjct: 278 QAYADYHD-LMDNTEELLRKLAIDILGTTIVKYGDLEFDFG---KPFERITLHDATIKYG 333

Query: 290 -------EILSDLGKEIPWGEDIDTEGEKLLGKYMLEN----EGAELY-----FIYRYPS 333
                  E L D  +     E +  E +K  G   + N    E AE +     F+   P+
Sbjct: 334 ADKGIVKEDLYDFDRAKATAERLGIEVQKSWGLGSIVNAIFEEVAEHHLIQPTFLNGSPA 393

Query: 334 EAKPFYIMKYEDKPEVCKAFDLEYRGVEISSG----GQREHRHDILVEQIREKGLNPESF 389
           E  P    + ++ PEV   F+L   G EI +G       E +++    Q+  K    +  
Sbjct: 394 EISPL-ARRNDENPEVTDRFELFIGGREIGNGFSELNDAEDQNERFDAQVAAKEAGDDEA 452

Query: 390 EF----YLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRRR 435
            F    ++ A E+G+PP  G GLG +RL M   +  +IR+VILFP  R++
Sbjct: 453 MFKDEDFVVALEHGLPPTAGEGLGIDRLAMLYANAPSIRDVILFPAMRQK 502


>pir||G81195 aspartyl-tRNA synthetase NMB0466 [imported] - Neisseria
           meningitidis (group B strain MD58)
           >gi|7225693|gb|AAF40903.1| (AE002403) aspartyl-tRNA
           synthetase [Neisseria meningitidis MC58]
           Length = 602
           
 Score =  132 bits (328), Expect = 1e-29
 Identities = 96/297 (32%), Positives = 148/297 (49%), Gaps = 29/297 (9%)

Query: 2   LRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFK 61
           +RT+Y   I+E+   + V V GWV   +D GG+ FI +RDREGIVQV         E F 
Sbjct: 1   MRTNYCGLISEQYLDQTVTVKGWVHRRRDHGGVIFIDLRDREGIVQVVIDPD--TPEAFA 58

Query: 62  LIPKLNSEDVIVVEGIVNFTPKAKLG-------FEIIPEKLEVISKAKTPLPLDPTGKVK 114
                 +E V+ + G V   P+            EI+ +++EV++ A TP P     +  
Sbjct: 59  AADSSRNEYVLSITGRVRNRPEGTTNDKMISGKIEILAKEIEVLNAAATP-PFQIDDENI 117

Query: 115 AELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTE 174
           +E + RL NR +DLR P +    ++R  V    R +   +GFI+I TP +  +  EG  +
Sbjct: 118 SE-NVRLTNRVIDLRRPVMQRNLRLRYQVAMGVRRYLDAQGFIDIETPMLTRSTPEGARD 176

Query: 175 -LFPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDA 232
            L P +    + F L QSPQL+KQ++M  G D+ ++I   FR E+    R   E   ID 
Sbjct: 177 YLVPSRVHPGEFFALPQSPQLFKQLLMVAGFDRYYQITKCFRDEDLRADRQ-PEFTQIDL 235

Query: 233 EMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEAL 289
           E +F+ +E+E+MD+ E +                ++ +  LN     FPR+ Y EA+
Sbjct: 236 ETSFL-NEDEIMDITEGM--------------AKQVFKDALNVDLGDFPRMPYSEAM 277


>sp|P13030|SYK1_ECOLI LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
           >gi|7428466|pir||SYECKT lysine--tRNA ligase (EC 6.1.1.6)
           - Escherichia coli >gi|146341|gb|AAA23959.1| (J03795)
           herC protein [Escherichia coli]
           >gi|887840|gb|AAA83071.1| (U28375) lysyl tRNA synthetase
           (LysRS), constitutive [Escherichia coli]
           >gi|1789256|gb|AAC75928.1| (AE000372) lysine tRNA
           synthetase, constitutive; suppressor of ColE1 mutation
           in primer RNA [Escherichia coli K12]
           Length = 505
           
 Score =  131 bits (327), Expect = 1e-29
 Identities = 124/473 (26%), Positives = 210/473 (44%), Gaps = 54/473 (11%)

Query: 3   RTHYSSEITEELNGKK----------VKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPK 52
           R H S ++  E +GK+          V VAG +   + +G   F+ ++D  G +Q+   +
Sbjct: 42  RDHTSDQLHAEFDGKENEELEALNIEVAVAGRMMTRRIMGKASFVTLQDVGGRIQLYVAR 101

Query: 53  KKVPQEIF-KLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTG 111
             +P+ ++ +   K +  D++  +G +  T   +L       +L +++KA  PLP    G
Sbjct: 102 DDLPEGVYNEQFKKWDLGDILGAKGKLFKTKTGELSIHCT--ELRLLTKALRPLPDKFHG 159

Query: 112 KVKAELDTRLDNRFMDL-RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATE 170
               E   R   R++DL  N    + FK+RS +    R+F    GF+E+ TP +      
Sbjct: 160 LQDQE--ARYRQRYLDLISNDESRNTFKVRSQILSGIRQFMVNRGFMEVETPMM--QVIP 215

Query: 171 GGTELFPLKYFEN----DAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNE 226
           GG    P     N    D +L  +P+LY + ++  G ++VFEI   FR  E  + RH  E
Sbjct: 216 GGAAARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFR-NEGISVRHNPE 274

Query: 227 AWSIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYD 286
              ++  MA+ + ++ +++L E L   +   +    E     +  +     KPF ++T  
Sbjct: 275 FTMMELYMAYADYKD-LIELTESLFRTLAQDILGKTEVTYGDVTLDFG---KPFEKLTMR 330

Query: 287 EALEILS-----------DLGKEIPWGEDIDTEGEKLLGKYMLE--NEGAELY-----FI 328
           EA++              D  K I     I  E    LG+ + E   E AE +     FI
Sbjct: 331 EAIKKYRPETDMADLDNFDSAKAIAESIGIHVEKSWGLGRIVTEIFEEVAEAHLIQPTFI 390

Query: 329 YRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSG----GQREHRHDILVEQIREKGL 384
             YP+E  P    + +  PE+   F+    G EI +G       E +    ++Q+  K  
Sbjct: 391 TEYPAEVSPL-ARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAQRFLDQVAAKDA 449

Query: 385 NPESFEFY----LRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDR 433
             +   FY    + A E+G+PP  G G+G +R++M   +   IR+VILFP  R
Sbjct: 450 GDDEAMFYDEDYVTALEHGLPPTAGLGIGIDRMVMLFTNSHTIRDVILFPAMR 502


>sp|Q9KGG4|SYK_BACHD LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
           >gi|10172710|dbj|BAB03817.1| (AP001507) lysyl-tRNA
           synthetase [Bacillus halodurans]
           Length = 501
           
 Score =  131 bits (327), Expect = 1e-29
 Identities = 126/475 (26%), Positives = 224/475 (46%), Gaps = 56/475 (11%)

Query: 2   LRTHYSSEITEELNGK--KVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEI 59
           ++  Y ++  EEL  +  +V +AG V   +  G   F  I+D  G +Q+   K  V  + 
Sbjct: 42  MKEKYDAKSKEELEEETHEVVLAGRVMTKRGKGKAGFAHIQDLTGQIQIYVRKDAVGDKS 101

Query: 60  FKLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDT 119
           + L   ++  D++ V+G+   T   +L  ++  +  ++++K+  PLP D    +K +++ 
Sbjct: 102 YDLFTSIDIGDIVGVKGVAFKTKVGELSVKV--QDFQLLTKSLRPLP-DKYHGLK-DVEQ 157

Query: 120 RLDNRFMDLR-NPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPL 178
           R   R++DL  NP V   F +RS + ++ R +    G++E+ TP +   +  GG    P 
Sbjct: 158 RYRQRYLDLIVNPEVRDTFVLRSKILQSMRRYLDDRGYLEVETPTM--HSIPGGASARPF 215

Query: 179 KYFEN----DAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEM 234
               N      ++  + +L+ + ++  G++KV+EIG +FR  E  +TRH  E   I+   
Sbjct: 216 VTHHNALDMTLYMRIAIELHLKRLIVGGMEKVYEIGRVFR-NEGVSTRHNPEFTMIELYE 274

Query: 235 AFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELN-EPKKPFPRITYDEALEILS 293
           A+ +  + +M+L E LI ++   V       +   E E+N EPK  + R+   EA++   
Sbjct: 275 AYADYND-IMELTELLIAHIAKDVLGTTT--ITYGEHEVNLEPK--WRRVHMVEAIK--E 327

Query: 294 DLGKEIPWGEDIDTEGEKLLGKY--------------------MLENEGAELYFIYRYPS 333
           + G +  W E  D E   L  ++                     +E +  +  F+Y +P 
Sbjct: 328 ETGVDF-WNEMSDEEARALAKEHNVPVKETMTYGHVVNEFFEHFVEEKLIQPTFVYGHPV 386

Query: 334 EAKPFYIMKYEDKPEVCKAFDLEYRGVEISSG--------GQREHRHDILVEQIREKGLN 385
              P    K  D P     F+L   G E ++          QR      LVE  RE+G +
Sbjct: 387 AISPL-AKKNPDDPRFTDRFELFIVGREHANAFSELNDPIDQRHRFEQQLVE--REQGDD 443

Query: 386 PESF--EFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRRRLVP 438
                 E ++ + EYGMPP GG G+G +RL+M + +  +IR+V+LFP+ R +  P
Sbjct: 444 EAHMMDEDFVESLEYGMPPTGGLGIGIDRLVMLLTNSPSIRDVLLFPQMRHKDSP 498


>pdb|1BBU|A Chain A, Lysyl-Trna Synthetase (Lyss) Complexed With Lysine
           >gi|11513776|pdb|1BBW|A Chain A, Lysyl-Trna Synthetase
           (Lyss)
           Length = 504
           
 Score =  131 bits (327), Expect = 1e-29
 Identities = 124/473 (26%), Positives = 210/473 (44%), Gaps = 54/473 (11%)

Query: 3   RTHYSSEITEELNGKK----------VKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPK 52
           R H S ++  E +GK+          V VAG +   + +G   F+ ++D  G +Q+   +
Sbjct: 41  RDHTSDQLHAEFDGKENEELEALNIEVAVAGRMMTRRIMGKASFVTLQDVGGRIQLYVAR 100

Query: 53  KKVPQEIF-KLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTG 111
             +P+ ++ +   K +  D++  +G +  T   +L       +L +++KA  PLP    G
Sbjct: 101 DDLPEGVYNEQFKKWDLGDILGAKGKLFKTKTGELSIHCT--ELRLLTKALRPLPDKFHG 158

Query: 112 KVKAELDTRLDNRFMDL-RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATE 170
               E   R   R++DL  N    + FK+RS +    R+F    GF+E+ TP +      
Sbjct: 159 LQDQE--ARYRQRYLDLISNDESRNTFKVRSQILSGIRQFMVNRGFMEVETPMM--QVIP 214

Query: 171 GGTELFPLKYFEN----DAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNE 226
           GG    P     N    D +L  +P+LY + ++  G ++VFEI   FR  E  + RH  E
Sbjct: 215 GGAAARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFR-NEGISVRHNPE 273

Query: 227 AWSIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYD 286
              ++  MA+ + ++ +++L E L   +   +    E     +  +     KPF ++T  
Sbjct: 274 FTMMELYMAYADYKD-LIELTESLFRTLAQDILGKTEVTYGDVTLDFG---KPFEKLTMR 329

Query: 287 EALEILS-----------DLGKEIPWGEDIDTEGEKLLGKYMLE--NEGAELY-----FI 328
           EA++              D  K I     I  E    LG+ + E   E AE +     FI
Sbjct: 330 EAIKKYRPETDMADLDNFDSAKAIAESIGIHVEKSWGLGRIVTEIFEEVAEAHLIQPTFI 389

Query: 329 YRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSG----GQREHRHDILVEQIREKGL 384
             YP+E  P    + +  PE+   F+    G EI +G       E +    ++Q+  K  
Sbjct: 390 TEYPAEVSPL-ARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAQRFLDQVAAKDA 448

Query: 385 NPESFEFY----LRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDR 433
             +   FY    + A E+G+PP  G G+G +R++M   +   IR+VILFP  R
Sbjct: 449 GDDEAMFYDEDYVTALEHGLPPTAGLGIGIDRMVMLFTNSHTIRDVILFPAMR 501


>emb|CAC11748.1| (AL445064) asparagine--tRNA ligase related protein [Thermoplasma
           acidophilum]
           Length = 329
           
 Score =  131 bits (326), Expect = 2e-29
 Identities = 96/324 (29%), Positives = 161/324 (49%), Gaps = 29/324 (8%)

Query: 116 ELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEG-GTE 174
           E++T ++     L  P +    K++SS+   T EF  + GFIE+  P II+  T+     
Sbjct: 20  EINTLIEEISEHLEKPELYHALKVQSSIRSITSEFLKERGFIEV-PPVIISVLTDPLNHP 78

Query: 175 LFP--LKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHN---TTRHLNEAWS 229
           +F   + Y+     L +S  ++ + +++   D++F   P  R EE +   T RHL E   
Sbjct: 79  VFDPTIDYYGYKYSLTKS-MIFHKHLLTKHFDRIFTFSPNIRLEEEDKVKTGRHLAEFTQ 137

Query: 230 IDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEAL 289
           +D EM    S +EVM L E +I+ +   ++ +NE++LK    +L  P KPF RI Y +A 
Sbjct: 138 LDLEMKGA-SRDEVMSLGEDMIIDLFKKIKRSNEEDLKFFGRDLRIPSKPFKRIAYLDAY 196

Query: 290 EILSDLGKEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEV 349
           +          +GED +         ++L +E  E ++I   P E + FY  +   +P +
Sbjct: 197 K---------QYGEDFE---------HILSSEMKEPFWIIDIPLEKREFYDREDPSRPGI 238

Query: 350 CKAFDLEY-RGV-EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFG 407
               DL Y  G  E  SGG+RE+    ++++I  KG   E F++Y+   + G+ P  GFG
Sbjct: 239 LVDMDLIYPEGFGEALSGGEREYELSRIIDRIHRKGQTEEQFKWYIEFAKEGLMPSAGFG 298

Query: 408 LGAERLIMRMLDIGNIREVILFPR 431
           +G ERL   +  +  I +   FP+
Sbjct: 299 IGIERLTRFICGLERIEDAHPFPK 322


>sp|Q9RHV9|SYK_BACST LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
           >gi|6681368|dbj|BAA88691.1| (AB012100) lysyl-tRNA
           synthetase [Bacillus stearothermophilus]
           Length = 494
           
 Score =  131 bits (325), Expect = 2e-29
 Identities = 127/478 (26%), Positives = 224/478 (46%), Gaps = 62/478 (12%)

Query: 3   RTHYSSEI--------TEELNGKKVKVA--GWVQEVKDLGGIKFIWIRDREGIVQVTAPK 52
           RTH + E+         EEL  ++++VA  G +   + +G   F  I+D  G +Q+   +
Sbjct: 34  RTHKAEELFELYGDLSKEELEEQQIEVAVAGRIMTKRGMGKAGFAHIQDVTGQIQIYVRQ 93

Query: 53  KKVPQEIFKLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGK 112
             V ++ ++L    +  D++ V G +  T   +L  ++     E ++KA  PLP    G 
Sbjct: 94  DDVGEQQYELFKISDLGDIVGVRGTMFKTKVGELSIKV--SSYEFLTKALRPLPEKYHGL 151

Query: 113 VKAELDTRLDNRFMDL-RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEG 171
              +++ R   R++DL  NP     F  RS + ++ R +    G++E+ TP + A A  G
Sbjct: 152 --KDIEQRYRQRYLDLIMNPESKKTFITRSLIIQSMRRYLDSHGYLEVETPMMHAVA--G 207

Query: 172 GTELFPLKYFEN----DAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEA 227
           G    P     N      ++  + +L+ + ++  GL+KV+EIG +FR  E  +TRH  E 
Sbjct: 208 GAAARPFITHHNALDMTLYMRIAIELHLKRLIVGGLEKVYEIGRVFR-NEGISTRHNPEF 266

Query: 228 WSIDAEMAFIESEEEVMDLLERLILYV---------INYVRENNEKELKILEFELNEPKK 278
             ++   A+ +  + +M L E LI ++         I Y     +   +     + +  K
Sbjct: 267 TMLELYEAYADFRD-IMKLTENLIAHIATEVLGTTKIQYGEHLVDLTPEWRRLHMVDAIK 325

Query: 279 PFPRITY------DEALEILSDLGKEIP----WGEDIDTEGEKLLGKYMLENEGAELYFI 328
            +  + +      +EA E+  + G E+     +G  ++   E+      +E++  +  FI
Sbjct: 326 EYVGVDFWRQMSDEEARELAKEHGVEVAPHMTFGHIVNEFFEQ-----KVEDKLIQPTFI 380

Query: 329 YRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSG--------GQREHRHDILVEQIR 380
           Y +P E  P    K  D P     F+L   G E ++          QR+   + L E  R
Sbjct: 381 YGHPVEISPL-AKKNPDDPRFTDRFELFIVGREHANAFTELNDPIDQRQRFEEQLKE--R 437

Query: 381 EKGLNPESFEF---YLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRRR 435
           E+G N E+ E    +L A EYGMPP GG G+G +RL+M + +  +IR+V+LFP+ R +
Sbjct: 438 EQG-NDEAHEMDEDFLEALEYGMPPTGGLGIGVDRLVMLLTNSPSIRDVLLFPQMRHK 494


>pir||F81831 aspartate--tRNA ligase (EC 6.1.1.12) NMA2019 [imported] - Neisseria
           meningitidis (group A strain Z2491)
           >gi|7380648|emb|CAB85238.1| (AL162757) aspartyl-tRNA
           synthetase [Neisseria meningitidis Z2491]
           Length = 602
           
 Score =  131 bits (325), Expect = 2e-29
 Identities = 97/297 (32%), Positives = 148/297 (49%), Gaps = 29/297 (9%)

Query: 2   LRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFK 61
           +RT+Y   I+E+   + V V GWV   +D GG+ FI +RDREGIVQV         E F 
Sbjct: 1   MRTNYCGLISEQYLDQTVTVKGWVHRRRDHGGVIFIDLRDREGIVQVVIDPD--TPEAFA 58

Query: 62  LIPKLNSEDVIVVEGIVNFTPKAKLG-------FEIIPEKLEVISKAKTPLPLDPTGKVK 114
                 +E V+ + G V   P+            EI+ +++EV++ A TP P     +  
Sbjct: 59  AADSARNEYVLSITGRVRNRPEGTTNDKMISGKIEILAKEIEVLNAAATP-PFQIDDENI 117

Query: 115 AELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTE 174
           +E + RL NR +DLR P +    ++R  V    R +   +GFI+I TP +  +  EG  +
Sbjct: 118 SE-NVRLTNRVIDLRRPVMQRNLRLRYQVAMGVRRYLDAQGFIDIETPMLTRSTPEGARD 176

Query: 175 -LFPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDA 232
            L P +    + F L QSPQL+KQ++M  G D+ ++I   FR E+    R   E   ID 
Sbjct: 177 YLVPSRVHPGEFFALPQSPQLFKQLLMVAGFDRYYQITKCFRDEDLRADRQ-PEFTQIDL 235

Query: 233 EMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEAL 289
           E +F+ +E+E+MD+ E +   V              L  +L +    FPR+ Y EA+
Sbjct: 236 ETSFL-NEDEIMDITEGMAKQVFK----------DALGVDLGD----FPRMPYSEAM 277


>pir||JC7205 lysine-tRNA ligase (AMP forming) (EC 6.1.1.6) - Bacillus
           stearothermophilus
           Length = 493
           
 Score =  131 bits (325), Expect = 2e-29
 Identities = 127/478 (26%), Positives = 224/478 (46%), Gaps = 62/478 (12%)

Query: 3   RTHYSSEI--------TEELNGKKVKVA--GWVQEVKDLGGIKFIWIRDREGIVQVTAPK 52
           RTH + E+         EEL  ++++VA  G +   + +G   F  I+D  G +Q+   +
Sbjct: 33  RTHKAEELFELYGDLSKEELEEQQIEVAVAGRIMTKRGMGKAGFAHIQDVTGQIQIYVRQ 92

Query: 53  KKVPQEIFKLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGK 112
             V ++ ++L    +  D++ V G +  T   +L  ++     E ++KA  PLP    G 
Sbjct: 93  DDVGEQQYELFKISDLGDIVGVRGTMFKTKVGELSIKV--SSYEFLTKALRPLPEKYHGL 150

Query: 113 VKAELDTRLDNRFMDL-RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEG 171
              +++ R   R++DL  NP     F  RS + ++ R +    G++E+ TP + A A  G
Sbjct: 151 --KDIEQRYRQRYLDLIMNPESKKTFITRSLIIQSMRRYLDSHGYLEVETPMMHAVA--G 206

Query: 172 GTELFPLKYFEN----DAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEA 227
           G    P     N      ++  + +L+ + ++  GL+KV+EIG +FR  E  +TRH  E 
Sbjct: 207 GAAARPFITHHNALDMTLYMRIAIELHLKRLIVGGLEKVYEIGRVFR-NEGISTRHNPEF 265

Query: 228 WSIDAEMAFIESEEEVMDLLERLILYV---------INYVRENNEKELKILEFELNEPKK 278
             ++   A+ +  + +M L E LI ++         I Y     +   +     + +  K
Sbjct: 266 TMLELYEAYADFRD-IMKLTENLIAHIATEVLGTTKIQYGEHLVDLTPEWRRLHMVDAIK 324

Query: 279 PFPRITY------DEALEILSDLGKEIP----WGEDIDTEGEKLLGKYMLENEGAELYFI 328
            +  + +      +EA E+  + G E+     +G  ++   E+      +E++  +  FI
Sbjct: 325 EYVGVDFWRQMSDEEARELAKEHGVEVAPHMTFGHIVNEFFEQ-----KVEDKLIQPTFI 379

Query: 329 YRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSG--------GQREHRHDILVEQIR 380
           Y +P E  P    K  D P     F+L   G E ++          QR+   + L E  R
Sbjct: 380 YGHPVEISPL-AKKNPDDPRFTDRFELFIVGREHANAFTELNDPIDQRQRFEEQLKE--R 436

Query: 381 EKGLNPESFEF---YLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRRR 435
           E+G N E+ E    +L A EYGMPP GG G+G +RL+M + +  +IR+V+LFP+ R +
Sbjct: 437 EQG-NDEAHEMDEDFLEALEYGMPPTGGLGIGVDRLVMLLTNSPSIRDVLLFPQMRHK 493


>emb|CAC08476.1| (AL392189) aspartyl-tRNA synthetase [Streptomyces coelicolor]
           Length = 587
           
 Score =  130 bits (324), Expect = 3e-29
 Identities = 92/296 (31%), Positives = 148/296 (49%), Gaps = 26/296 (8%)

Query: 3   RTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKL 62
           R+H   E+     G  V+++GW+   +DLGGI FI +RD  GI Q+ A   +   E ++ 
Sbjct: 5   RSHTCGELRSSDVGTDVRLSGWLHNRRDLGGILFIDLRDHYGITQLVA---RPGTEAYEA 61

Query: 63  IPKLNSEDVIVVEGIV------NFTPKAKLG-FEIIPEKLEVISKAKTPLPLDPTGKVKA 115
           + KL  E  + V+G V      N  P    G  E+   ++E++  A+ PLP     +   
Sbjct: 62  LDKLTKESTVRVDGKVVSRGADNINPDLPTGEVEVEVGEVELLGAAQ-PLPFTINTEDGV 120

Query: 116 ELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTEL 175
             + RL+ RF+DLR  R+     +R+SV  + R      GF E+ TP + AT+ EG  + 
Sbjct: 121 NEERRLEYRFLDLRRERMHRNIMLRTSVISSIRSKMVALGFNEMATPILTATSPEGARDF 180

Query: 176 FPLKYFENDAFLA--QSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAE 233
                     F A  Q+PQ +KQ++M +G D+ F+I P FR E+    R   E + +D E
Sbjct: 181 VVPSRLHAGRFYALPQAPQQFKQLLMISGFDRYFQIAPCFRDEDARADRSPGEFYQLDVE 240

Query: 234 MAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEAL 289
           M+F+E +E+V   +E+L+  +  +    N + +            PFPRI + EA+
Sbjct: 241 MSFVE-QEDVFRPIEQLMTEL--FEEFGNGRHV----------TSPFPRIPFREAM 283


>sp|P37477|SYK_BACSU LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
           >gi|2127132|pir||S66111 lysine--tRNA ligase (EC 6.1.1.6)
           lysS - Bacillus subtilis >gi|467470|dbj|BAA05316.1|
           (D26185) lysyl-tRNA thynthetase [Bacillus subtilis]
           >gi|2632349|emb|CAB11858.1| (Z99104) lysyl-tRNA
           synthetase [Bacillus subtilis]
           Length = 499
           
 Score =  130 bits (323), Expect = 4e-29
 Identities = 130/475 (27%), Positives = 220/475 (45%), Gaps = 56/475 (11%)

Query: 3   RTHYSSEIT--------EELNGKKVKV--AGWVQEVKDLGGIKFIWIRDREGIVQVTAPK 52
           RTH S E+         EEL  K ++V  AG +   +  G   F  ++D EG +Q+   K
Sbjct: 39  RTHQSQEVISAYQDLTKEELEEKAIEVTIAGRMMTKRGKGKAGFAHLQDLEGQIQIYVRK 98

Query: 53  KKVPQEIFKLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGK 112
             V  + +++    +  D+I V G V  T   +L  +      E+++KA  PLP D    
Sbjct: 99  DSVGDDQYEIFKSSDLGDLIGVTGKVFKTNVGELSVKAT--SFELLTKALRPLP-DKYHG 155

Query: 113 VKAELDTRLDNRFMDLR-NPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEG 171
           +K +++ R   R++DL  NP     F  RS + +A R +    G++E+ TP +   +  G
Sbjct: 156 LK-DVEQRYRQRYLDLIVNPDSKHTFITRSKIIQAMRRYLDDHGYLEVETPTM--HSIPG 212

Query: 172 GTELFPLKYFEN----DAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEA 227
           G    P     N      ++  + +L+ + ++  GL+KV+EIG +FR  E  +TRH  E 
Sbjct: 213 GASARPFITHHNALDIPLYMRIAIELHLKRLIVGGLEKVYEIGRVFR-NEGVSTRHNPEF 271

Query: 228 WSIDAEMAFIESEEEVMDLLERLILYV---------INYVRENNEKELKILEFELNEPKK 278
             I+   A+ + ++ +M L E L+ ++         I Y  E  + + +     + +  K
Sbjct: 272 TMIELYEAYADYKD-IMSLTENLVAHIAQEVLGTTTIQYGEEQIDLKPEWKRIHMVDAVK 330

Query: 279 PFPRITYDEALEILSDLGKEIPWGEDIDTEGEKLLGKYM-------LENEGAELYFIYRY 331
               + + E  E+  +  +E     +++ +    +G  +       +E    +  FIY +
Sbjct: 331 EATGVDFWE--EVTVEQAREYAKEHEVEIKDSMTVGHIINEFFEQKIEETLIQPTFIYGH 388

Query: 332 PSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSG--------GQREHRHDILVEQIREKG 383
           P E  P      ED P     F+L   G E ++          QRE     L E  RE G
Sbjct: 389 PVEISPLAKKNPED-PRFTDRFELFIVGREHANAFTELNDPIDQRERFEAQLKE--REAG 445

Query: 384 LNPESF---EFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRRR 435
            N E+    E ++ A EYGMPP GG G+G +RL+M + +  +IR+V+LFP+ R+R
Sbjct: 446 -NDEAHLMDEDFVEALEYGMPPTGGLGIGIDRLVMLLTNAPSIRDVLLFPQMRQR 499


>sp|Q53638|SYK_STAAU LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
           >gi|567884|gb|AAA53114.1| (L36472) lysyl-tRNA synthetase
           [Staphylococcus aureus]
           Length = 495
           
 Score =  130 bits (323), Expect = 4e-29
 Identities = 118/457 (25%), Positives = 213/457 (45%), Gaps = 42/457 (9%)

Query: 9   EITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNS 68
           E+ E+     V +AG +   +  G   F  ++D  G +Q+   K +V  + F L    + 
Sbjct: 51  ELVEKEADSHVAIAGRLMTKRGKGKAGFAHVQDLAGQIQIYVRKDQVGDDEFDLWKNADL 110

Query: 69  EDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDL 128
            D++ VEG++  T   +L  +   +K  +++K+  PLP    G    +++ R   R++DL
Sbjct: 111 GDIVGVEGVMFKTNTGELSVKA--KKFTLLTKSLRPLPDKFHGL--QDIEQRYRQRYLDL 166

Query: 129 -RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDA-- 185
             N      F  RS + +  R +   +GF+E+ TP +   A       F   +   DA  
Sbjct: 167 ITNEDSTRTFINRSKIIQEMRNYLNNKGFLEVETPMMHQIAGGAAARPFVTHHNALDATL 226

Query: 186 FLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMD 245
           ++  + +L+ + ++  GL+KV+EIG +FR  E  +TRH  E   I+   A+ +  + +MD
Sbjct: 227 YMRIAIELHLKRLIVGGLEKVYEIGRVFR-NEGVSTRHNPEFTMIELYEAYADYHD-IMD 284

Query: 246 LLERLILYVINYVR--------------ENNEKELKILEFELNEPKKPFPRITYDEALEI 291
           L E ++ ++ N V               E+    L I++         F  +  DE  + 
Sbjct: 285 LTESMVRHIANEVLGSAKVQYNGETIDLESAWTRLHIVDAVKEATGVDFYEVKSDEERKA 344

Query: 292 LS-----DLGKEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDK 346
           L+     ++   + +G  ++   E+ + + +++       FIY +P+E  P      ED 
Sbjct: 345 LAKEHGIEIKDTMKYGHILNEFFEQKVEETLIQPT-----FIYGHPTEISPLAKKNPED- 398

Query: 347 PEVCKAFDLEYRG-------VEISSGGQREHRHDI-LVEQIREKGLNPESFEFYLRAFEY 398
           P     F+L   G        E++    ++ R +  LVE+ +      E  E Y+ A EY
Sbjct: 399 PRFTDRFELFIVGREHANRFTELNDPIDQKGRFEAQLVEKAQGNDEAHEMDEDYIEALEY 458

Query: 399 GMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRRR 435
           GMPP GG G+G +RL+M + D  +IR+V+LFP  R++
Sbjct: 459 GMPPTGGLGIGIDRLVMLLTDSPSIRDVLLFPYMRQK 495


>pir||S77851 probable aspartate--tRNA ligase (EC 6.1.1.12) - Mycoplasma
           capricolum
           Length = 524
           
 Score =  129 bits (321), Expect = 6e-29
 Identities = 98/301 (32%), Positives = 155/301 (50%), Gaps = 34/301 (11%)

Query: 1   MLRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF 60
           M RTH   E+T +   +KV + GWV++++ LG + FI ++DR GI Q+      + QE  
Sbjct: 1   MKRTHTCGELTLQNVDQKVILQGWVKKIRKLGAMVFIDLKDRYGITQLV-----IEQENI 55

Query: 61  KLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISK--------AKTPLPLDPTGK 112
            LI  L +E VI + GIV    +  +  E+I  ++EVI K          TP  L+    
Sbjct: 56  NLINNLKNEYVIEISGIV--VKRKSVNKELITGEIEVIVKDLLVINKSELTPFVLE--ND 111

Query: 113 VKAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGG 172
           V    DTRL  R++DLR   + +   IR+ +    R +     F+E+ TP    +  EG 
Sbjct: 112 VNVNEDTRLTYRYLDLRRQVMQNNLIIRAKINHIIRNYLTDLNFLEVETPYFAKSTPEGA 171

Query: 173 TE-LFPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSI 230
              L P +  +N  + L QSPQL+KQ++M +G+D+ ++I   FR E+    R   E   +
Sbjct: 172 RHFLVPSRLNKNKFYALPQSPQLFKQLLMISGIDRYYQIVRCFRDEDLRIDRQ-PEFTQL 230

Query: 231 DAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALE 290
           D EM+F  S E+VM + E LI  ++        KE+K  E      K+P  R++Y +A++
Sbjct: 231 DLEMSFATS-EDVMQISESLIKKIL--------KEVKNFEI-----KEPLLRLSYKDAID 276

Query: 291 I 291
           +
Sbjct: 277 L 277


>sp|Q9X231|SYK_THEMA LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
           >gi|7437571|pir||C72221 lysine--tRNA ligase (EC 6.1.1.6)
           - Thermotoga maritima  (strain MSB8)
           >gi|4982282|gb|AAD36772.1|AE001810_11 (AE001810)
           lysyl-tRNA synthetase [Thermotoga maritima]
           Length = 502
           
 Score =  128 bits (318), Expect = 1e-28
 Identities = 130/445 (29%), Positives = 204/445 (45%), Gaps = 36/445 (8%)

Query: 12  EELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPK-LNSED 70
           E L  +K+  AG V  ++  G   F  ++D  G +Q       V +E   L  + +   D
Sbjct: 48  EVLESEKLSFAGRVMSIRHHGKTAFFHMKDDTGRIQAYIKADSVGKEKMDLFKRHVKIGD 107

Query: 71  VIVVEGIVNFTPKAKLG-FEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLR 129
            + V G   F  K+K G   I  ++  ++SKA  PLP    G    E+  R   R+++L 
Sbjct: 108 FVGVRG---FPFKSKTGELTIYVQEYTLLSKALRPLPEKWHGIKDKEIIYR--QRYLELI 162

Query: 130 -NPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFP----LKYFEND 184
            N   +  FK R    R  REF    GFIE+ TP  I     GG E  P    L  F+ D
Sbjct: 163 VNDEAIERFKKRFKAVRVIREFLNSRGFIEVETP--ILHYVTGGAEARPFVTHLNVFDID 220

Query: 185 AFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVM 244
            +L  +P+LY + ++  G +K++EIG  FR  E  + +H  E  SI+   A+ +  + +M
Sbjct: 221 MYLRIAPELYLKRLIVGGFEKIYEIGKNFR-NEGISYKHSPEFTSIEIYQAYADYND-MM 278

Query: 245 DLLERLILYVINYVRENNEKELKILEFELNEP-KKPFPRITYDEAL--EILSD-----LG 296
           DL E LI+ V+       +   +  E +   P K+   R    E L  +IL D     L 
Sbjct: 279 DLTEELIVEVVKRTCGTLKISYQGKEIDFTPPWKRVRMRDFLKEKLGVDILEDPDEVLLK 338

Query: 297 KEIPWGEDIDTEGEK-LLGKY--MLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAF 353
           K    G +++ +    L+ K   ++E E     FI  +P    P    ++ + P + + F
Sbjct: 339 KLEEHGVELEIKNRAHLIDKLRDLVEEELVNPTFIIDHPVVISPL-AKRHREDPRLTERF 397

Query: 354 DLEYRGVEISSGGQREH----RHDILVEQIREKGLNPESFEF----YLRAFEYGMPPHGG 405
           +L   G EI++     +    ++   +EQ + +    E        ++RA EYGMPP GG
Sbjct: 398 ELIIFGREIANAFSELNDPVDQYQRFLEQAKMREEGDEEAHMMDLDFVRALEYGMPPTGG 457

Query: 406 FGLGAERLIMRMLDIGNIREVILFP 430
            G+G +RL M + D   IR+VI FP
Sbjct: 458 LGIGLDRLFMFITDSPTIRDVIPFP 482


>pir||E81660 aspartyl-tRNA synthetase TC0829 [imported] - Chlamydia muridarum
           (strain Nigg) >gi|7190856|gb|AAF39629.1| (AE002349)
           aspartyl-tRNA synthetase [Chlamydia muridarum]
           Length = 582
           
 Score =  128 bits (318), Expect = 1e-28
 Identities = 97/304 (31%), Positives = 161/304 (52%), Gaps = 40/304 (13%)

Query: 3   RTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKL 62
           RTH  +E++    G+ V+++GWV   ++ GG+ FI +RDR GI Q+   +++ P E+ +L
Sbjct: 4   RTHKCNELSLNHVGEHVRLSGWVHRYRNHGGVVFIDLRDRFGITQIVCRQEENP-ELHRL 62

Query: 63  IPKLNSEDVIVVEGIVNFTPKAKLG-----------FEIIPEKLEVISKAKTPLPLDPTG 111
           + ++ SE V+ VEG+V     A+LG            E+    LEV+S+A+  LP   + 
Sbjct: 63  MDQVRSEWVLCVEGLV----CARLGGMENPNLVTGSIEVEVSHLEVLSRAQN-LPFSISD 117

Query: 112 K-VKAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATE 170
           + +    + RL  R++D+R   ++     R  V  A R++  ++GF E+ TP +  +  E
Sbjct: 118 EHINVNEELRLTYRYLDMRRGDIVDRLMCRHKVMLACRQYLDEQGFTEVVTPVLGKSTPE 177

Query: 171 GGTE-LFPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAW 228
           G  + L P + +  + + L QSPQL+KQ++M  GLD+ F+I   FR E+    R   E  
Sbjct: 178 GARDYLVPSRIYPGNFYALPQSPQLFKQILMVGGLDRYFQIATCFRDEDLRADRQ-PEFS 236

Query: 229 SIDAEMAFIESEEEVMDLLERLI--LYVINYVRENNEKELKILEFELNEPKKPFPRITYD 286
            ID EM+F    E++  ++E L+  L+ +  +      EL I          PF R+TY 
Sbjct: 237 QIDMEMSF-GGPEDLFPIVEELVTRLFAVKGI------ELSI----------PFQRMTYQ 279

Query: 287 EALE 290
           EA E
Sbjct: 280 EAKE 283


>sp|Q43990|SYK_ACICA LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
           >gi|1359473|emb|CAA86924.1| (Z46863) lysyl-tRNA-synthase
           [Acinetobacter sp. ADP1]
           Length = 509
           
 Score =  127 bits (317), Expect = 2e-28
 Identities = 128/479 (26%), Positives = 212/479 (43%), Gaps = 65/479 (13%)

Query: 3   RTHYSSEITEELNG-----------KKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAP 51
           R HY++++ E+                VKVAG V     L    F+ I+D  G +Q+   
Sbjct: 48  REHYAADLQEQFKDIDKAQIEGSDKTYVKVAGRVM----LNRGSFMVIQDMTGRIQLYVD 103

Query: 52  KKKVPQEIFKLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTG 111
           +K +P +  + I  L+  D+I  EG +  + K  L   +  E  E+++K+  PLP    G
Sbjct: 104 RKGLPADTLETIKSLDLGDIIAAEGYIGRSGKGDLYVHL--EGFELLTKSLRPLPDKFHG 161

Query: 112 KVKAELDTRLDNRFMDLR-NPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATE 170
               E   R   R++DL  N      F+IR+ V    R F   + F+E+ TP +      
Sbjct: 162 LTDTEAKYR--KRYLDLIVNEETRKTFEIRAQVVAGIRAFLTNQRFMEVETPMM--HVIP 217

Query: 171 GGTELFPLKYFEN----DAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNE 226
           GG    P     N    + +L  +P+LY + ++  G ++VFEI   FR  E  +TRH  E
Sbjct: 218 GGASAQPFVTHHNALDMELYLRIAPELYLKRLVVGGFERVFEINRNFR-NEGVSTRHNPE 276

Query: 227 AWSIDAEMAFIESEEEVM---DLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRI 283
              I+   A+ + ++ +    ++LE+L L ++         E+          K PF +I
Sbjct: 277 FTMIEFYQAYADYKDLMQLTENMLEKLALDILGTTDVPYGDEVYSF-------KGPFKKI 329

Query: 284 T-YDEALEILSDLGKE--------IPWGEDIDTEGEKL---LGKYM-------LENEGAE 324
           + +D  LE   D   E          + +D+  E  K    LGK         +E +  +
Sbjct: 330 SMFDAILEHNPDFTPENVNDREFLAKFTQDVLKEQVKPGFGLGKLQTIVFEETVETKLRQ 389

Query: 325 LYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSGGQREH----RHDILVEQIR 380
             FI  YP+E  P    + +D P +   F+    G E+++G    +    + +    Q+ 
Sbjct: 390 PTFITEYPAETSPL-ARRNDDNPHITDRFEFFIGGRELANGFSELNDPIDQAERFQAQVA 448

Query: 381 EKGLNPESFEFY----LRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRRR 435
           EK    +    Y    + A EYG+PP  G G+G +RL+M   +  +IR+V+LFP  RR+
Sbjct: 449 EKDAGDDEAMHYDADFIEALEYGLPPTAGQGIGIDRLVMIFANAPSIRDVLLFPHMRRK 507


>sp|P43817|SYD_HAEIN ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
           >gi|1073870|pir||E64061 aspartate--tRNA ligase (EC
           6.1.1.12) - Haemophilus influenzae (strain Rd KW20)
           >gi|1573287|gb|AAC21981.1| (U32717) aspartyl-tRNA
           synthetase (aspS) [Haemophilus influenzae Rd]
           Length = 588
           
 Score =  127 bits (316), Expect = 2e-28
 Identities = 86/259 (33%), Positives = 134/259 (51%), Gaps = 14/259 (5%)

Query: 1   MLRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF 60
           M+RTHY   +     G+ V ++GWV   +DLGG+ FI +RDR+GIVQV    K   Q+  
Sbjct: 1   MMRTHYCGALNRNNIGQDVTLSGWVHRRRDLGGLIFIDMRDRDGIVQVCFDPKY--QDAL 58

Query: 61  KLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISK------AKTPLPLDPTGKVK 114
                L +E  I ++G V   P  ++   +   ++EV++K      A   LPLD      
Sbjct: 59  TAAAGLRNEFCIQIKGEVIARPDNQINKNMATGEVEVLAKELRIYNASDVLPLDFNQNNT 118

Query: 115 AELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTE 174
            E   RL  R++DLR P +    K R+ +    R F    GF++I TP +     EG  +
Sbjct: 119 EE--QRLKYRYLDLRRPEMAQRLKTRAKITSFVRRFMDDNGFLDIETPMLTKATPEGARD 176

Query: 175 -LFPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDA 232
            L P +  +   + L QSPQL+KQ++M +G D+ ++I   FR E+    R   E   ID 
Sbjct: 177 YLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQ-PEFTQIDV 235

Query: 233 EMAFIESEEEVMDLLERLI 251
           E +F+ +  EV +++ER++
Sbjct: 236 ETSFL-TAPEVREIMERMV 253


>sp|Q9ZE17|SYD_RICPR ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
           >gi|7437607|pir||F71724 aspartate--tRNA ligase (EC
           6.1.1.12) - Rickettsia prowazekii
           >gi|3860712|emb|CAA14613.1| (AJ235270) ASPARAGINYL-TRNA
           SYNTHETASE (aspS) [Rickettsia prowazekii]
           Length = 605
           
 Score =  126 bits (313), Expect = 6e-28
 Identities = 86/295 (29%), Positives = 148/295 (50%), Gaps = 23/295 (7%)

Query: 3   RTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKL 62
           RTH  +E+     G++VK++GWV   +D G + FI +RD  GI Q+    +   Q++   
Sbjct: 5   RTHNCNELQLSNVGQEVKLSGWVHRRRDHGNLVFIDLRDHYGITQIVFTDQN--QQLMYD 62

Query: 63  IPKLNSEDVIVVEGIV------NFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAE 116
             +L  E VI V G V          K   G+  +     ++  A +PLP     + +A 
Sbjct: 63  ASRLCYESVITVSGTVVARSLDTINNKLPTGYVEVLAMECIVESASSPLPFVINNEKEAP 122

Query: 117 LDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTE-L 175
            ++RL +RF+DLR  ++ +   +RS V    R      GF E+ TP + +++ EG  + L
Sbjct: 123 EESRLKHRFLDLRREKLHNNIILRSQVIAHIRHLMIARGFTELQTPILTSSSPEGARDFL 182

Query: 176 FPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEM 234
            P +      + L Q+PQ +KQ++M  G D+ F+I P FR E+    R   E + +D EM
Sbjct: 183 VPSRIHPGKFYALPQAPQQFKQLLMVAGFDRYFQIAPCFRDEDARADRSPGEFYQLDLEM 242

Query: 235 AFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEAL 289
           +F+ ++E++ + +E  +LY + + +  N+               PF RI Y+E++
Sbjct: 243 SFV-TQEDIFNTIEP-VLYDL-FTKFTNK----------TVSNTPFVRIPYNESM 284


>gb|AAF46510.1| (AE003447) CG12141 gene product [Drosophila melanogaster]
           Length = 572
           
 Score =  126 bits (313), Expect = 6e-28
 Identities = 133/464 (28%), Positives = 209/464 (44%), Gaps = 56/464 (12%)

Query: 12  EELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGI-VQVTAPKKKVPQEI-FKL-IPKLNS 68
           E L   K+ VAG V  +++ G     +    EG+ VQV A  K    E  F++   KL  
Sbjct: 100 ETLENVKLSVAGRVHAIRESGAKLIFYDLRGEGVKVQVMASAKSYKSEADFEIDTSKLRR 159

Query: 69  EDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDL 128
            D+I V G    T K +L   ++P +++++S     LP    G    E  TR   R++DL
Sbjct: 160 GDIIGVVGHPGKTKKGELS--VMPSEIKLLSPCLHMLPHLHFGLKDKE--TRYRQRYLDL 215

Query: 129 -RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDA-- 185
             N  V   F+IR+ +    R+F  + GF+EI TP +   A  GG    P     ND   
Sbjct: 216 ILNNNVREKFQIRAKIISYVRQFLDRLGFLEIETPMMNMIA--GGATAKPFVTHHNDLKM 273

Query: 186 --FLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEV 243
             F+  +P+LY +M++  GLD+V+EIG  FR E  + T H  E  + +  MA+ +  + +
Sbjct: 274 DLFMRIAPELYHKMLVVGGLDRVYEIGRQFRNEGIDLT-HNPEFTTCEFYMAYADYAD-I 331

Query: 244 MDLLERLILYVINYVR------------ENNEKEL------------KILEFELNEPKKP 279
           MD+ E+L+  ++  +R            E  E+EL            K LE +L      
Sbjct: 332 MDITEQLVSGMVKAIRGSYKVIYHPEGPEGPEQELDFTPPFKRVSMIKTLEEKLQVKFPA 391

Query: 280 FPRITYDEALEILSDLGK----EIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEA 335
                  E  + LS L      E P         +KL+G++ +E       FI  +P   
Sbjct: 392 ADTFNSPETNQFLSQLCAKHQVECPAPRTTARLLDKLVGEF-IEEFCVNPTFICEHPQIM 450

Query: 336 KPFYIMKYEDK-PEVCKAFDLEYRGVEISSGGQREH----RHDILVEQIREKGLNPESFE 390
            P  + KY    P + + F+L     EI +     +    + +   +Q  +K    +  +
Sbjct: 451 SP--LAKYHRSIPGLTERFELFVAKKEICNAYTELNDPVVQRERFEQQASDKAAGDDEAQ 508

Query: 391 F----YLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFP 430
                +  + EYG+PP GGFG+G +RL M + D  NI+EV+LFP
Sbjct: 509 LVDENFCTSLEYGLPPTGGFGMGIDRLAMFLTDSNNIKEVLLFP 552


>pir||B81858 lysine--tRNA ligase (EC 6.1.1.6) NMA1638 [imported] - Neisseria
           meningitidis (group A strain Z2491)
           >gi|7380280|emb|CAB84866.1| (AL162756) lysyl-tRNA
           synthetase [Neisseria meningitidis Z2491]
           Length = 503
           
 Score =  126 bits (313), Expect = 6e-28
 Identities = 129/465 (27%), Positives = 210/465 (44%), Gaps = 45/465 (9%)

Query: 2   LRTHYSSEITEELN--GKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEI 59
           L   Y     EEL+  G  VKVAG +   + +G   F  I+D  G +Q+    K V QE+
Sbjct: 49  LHAQYGEIGKEELDPQGIPVKVAGRMMLKRQMGKASFATIQDVSGQIQLYLNNKGVSQEV 108

Query: 60  FKLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDT 119
                  +  D++  EG +  T   +L   +    + ++SK+  PLP    G   ++ +T
Sbjct: 109 LDDFNHWDLGDIVGAEGTLFKTNHGELTVRV--SGIRLLSKSLRPLPDKHKGL--SDQET 164

Query: 120 RLDNRFMDL-RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPL 178
           +   R++DL  N    + F  RS + ++ R F   E ++E+ TP +      GG    P 
Sbjct: 165 KYRQRYVDLIANEESRNTFIKRSQIIQSVRNFMVGEHYLEVETPMM--HPIPGGATAKPF 222

Query: 179 KYFEN----DAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEM 234
               N      +L  +P+LY + ++  GL++VFEI   FR  E  + RH  E   I+   
Sbjct: 223 VTHHNALDIPLYLRIAPELYLKRLVVGGLERVFEINRSFR-NEGMSVRHNPEFTMIEFYE 281

Query: 235 AFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALE---- 290
           AF + E  +M + E +I    + V           E +L   + PF R+T  EA++    
Sbjct: 282 AFSDYER-MMQMAEDIIRNASHTVNGTANITYNGKEVDL---ESPFERLTILEAIKKYNP 337

Query: 291 -ILSDLGKEIPW-GEDIDTEGEKL-----LGKYML-------ENEGAELYFIYRYPSEAK 336
               +   +  W  ++I   GE L     +G   L       E +     FI  YP E  
Sbjct: 338 HYTDEQLNDAEWLKKEIVKHGESLPPSPGIGSLQLALFEGCAEGKLWNPTFIVDYPVEVS 397

Query: 337 PFYIMKYEDKPEVCKAFDLEYRGVEISSG----GQREHRHDILVEQIREKGL-NPESFEF 391
           P      + K  + + F+L   G E+++G       E + +    Q+ +K   + E+  +
Sbjct: 398 PL-ARASDTKQGLTERFELFVVGRELANGYSELNDPEDQAERFKAQVAQKDAGDDEAMHY 456

Query: 392 ---YLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDR 433
              Y+RA E+G+PP GG G+G +RL+M + D   IR+VILFP+ R
Sbjct: 457 DADYIRAMEFGLPPTGGCGIGIDRLVMLLTDSQTIRDVILFPQMR 501


>sp|Q49158|SYK_MYCFE LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
           >gi|1263074|gb|AAC43988.1| (U50826) lysyl-tRNA
           synthetase [Mycoplasma fermentans]
           Length = 488
           
 Score =  125 bits (310), Expect = 1e-27
 Identities = 125/463 (26%), Positives = 226/463 (47%), Gaps = 48/463 (10%)

Query: 2   LRTHYSSEITEELNGKKVK--VAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEI 59
           L   Y     EEL  KKVK  ++G +   +      F+ ++DR+G +QV   KK+ P E+
Sbjct: 41  LNKKYGQFAREELEAKKVKKNISGRLITARG----PFLVLKDRKGTIQVYFNKKENP-EL 95

Query: 60  FKLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDT 119
            K++   +  D++ V G++  T   ++   +  + +++++KA  PLP    G    E   
Sbjct: 96  TKIVETFDLGDILWVRGLLMKTHTCEM--TVRAQDIQLLTKALKPLPDKFHGLTDTE--E 151

Query: 120 RLDNRFMDL-RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPL 178
           R  +R++DL  NP   + F +R+ + +  R++F K  ++E  TP +    +    + F  
Sbjct: 152 RYRHRYLDLITNPESRNTFIMRTKIVQWIRDYFNKLDYLEAETPFLHDYLSGAAAKPFTT 211

Query: 179 KY--FENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAF 236
            +     D  L  + ++  + ++  G ++V+E+G IFR E ++TT H  E  +I+   A+
Sbjct: 212 HHNSLNQDFVLRIATEIPLKKLVVGGFERVYEMGRIFRNEGYDTT-HNPEFTTIEFYEAY 270

Query: 237 IESEEEVMDLLERLIL----------YVINYVRENNEKELK---ILEFELNEPKKPFPRI 283
             + E +M+  E LI           +V N V  +  K  K   +++    +  K F +I
Sbjct: 271 -SNVEGMMNRTETLIKELCKKIGKSKFVTNGVEVDLSKPFKRVNMIDEVSKKTGKNFRKI 329

Query: 284 TYDEALEILSDLGKEIPWGEDIDTEGEKLLGKY--MLENEGAELYFIYRYPSEAKPFYIM 341
           T +EA+E+      +I   E   T G  +   Y  ++E    +  F+Y +P E  P  + 
Sbjct: 330 TLEEAIEVAKAYKIKI---EKFFTIGHIINALYEELVEPTLIQPTFLYGHPIEISP--LS 384

Query: 342 KYEDKPEVCKAFDL-----EYRGV--EISSGGQREHRHDILVEQIREKGLNPESFEF--- 391
              D P   +  +L     EY  +  E+S    +  R +  +E+ + KG N E+ +    
Sbjct: 385 AKSDDPRFTERAELFINTKEYANMYTELSDPIDQLERFESQLEE-KNKG-NDEASDIDYD 442

Query: 392 YLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRR 434
           ++ A EYGMPP GG G+G +RL+M + +  +IR+V+LFP  +R
Sbjct: 443 FVDALEYGMPPTGGCGIGIDRLVMLLTETDSIRDVLLFPTLKR 485


>sp|O84546|SYD_CHLTR ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
           >gi|7437586|pir||G71500 aspartate--tRNA ligase (EC
           6.1.1.12) - Chlamydia trachomatis (serotype D, strain
           UW3/Cx) >gi|3328981|gb|AAC68144.1| (AE001325) Aspartyl
           tRNA Synthetase [Chlamydia trachomatis]
           Length = 582
           
 Score =  125 bits (310), Expect = 1e-27
 Identities = 92/296 (31%), Positives = 156/296 (52%), Gaps = 28/296 (9%)

Query: 3   RTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKL 62
           RTH  +E++ +  G+ V+++GWV   ++ GG+ FI +RD  GI Q+   +++ P E+ +L
Sbjct: 4   RTHKCNELSLDHVGEHVRLSGWVHRYRNHGGVVFIDLRDCFGITQIVCRQEENP-ELHQL 62

Query: 63  IPKLNSEDVIVVEGIV------NFTPKAKLG-FEIIPEKLEVISKAKTPLPLDPTGK-VK 114
           + ++ SE V+ VEG+V         P    G  E+    LEV+S+A+  LP   + + + 
Sbjct: 63  MDQVRSEWVLCVEGLVCARLEGMENPNLVTGSIEVEVSSLEVLSRAQN-LPFSISDEHIN 121

Query: 115 AELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTE 174
              + RL  R++D+R   ++     R  V  A R++  ++GF E+ TP +  +  EG  +
Sbjct: 122 VNEELRLTYRYLDMRRGDILDRLMCRHKVMLACRQYLDEQGFTEVVTPILGKSTPEGARD 181

Query: 175 -LFPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDA 232
            L P + +  + + L QSPQL+KQ++M  GLD+ F+I   FR E+    R   E   ID 
Sbjct: 182 YLVPSRIYPGNFYALPQSPQLFKQILMVGGLDRYFQIATCFRDEDLRADRQ-PEFTQIDM 240

Query: 233 EMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEA 288
           EM+F    E++  ++E L+               ++   +  E K PF R+TY EA
Sbjct: 241 EMSF-GGPEDLFPVVEELV--------------ARLFAVKGIELKAPFLRMTYQEA 281


>pir||C81086 lysyl-tRNA synthetase, heat inducible NMB1425 [imported] -
           Neisseria meningitidis (group B strain MD58)
           >gi|7226664|gb|AAF41786.1| (AE002491) lysyl-tRNA
           synthetase, heat inducible [Neisseria meningitidis MC58]
           Length = 503
           
 Score =  125 bits (310), Expect = 1e-27
 Identities = 129/465 (27%), Positives = 209/465 (44%), Gaps = 45/465 (9%)

Query: 2   LRTHYSSEITEELN--GKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEI 59
           L   Y     EEL+  G  VKVAG +   + +G   F  I+D  G +Q+    K V QE+
Sbjct: 49  LHAQYGEIGKEELDPQGIPVKVAGRMMLKRQMGKASFATIQDVSGQIQLYLNNKGVSQEV 108

Query: 60  FKLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDT 119
                  +  D++  EG +  T   +L   +    + ++SK+  PLP    G   ++ +T
Sbjct: 109 LDDFNHWDLGDIVGAEGTLFKTNHGELTVRV--SGIRLLSKSLRPLPDKHKGL--SDQET 164

Query: 120 RLDNRFMDL-RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPL 178
           +   R++DL  N    + F  RS + ++ R F   E ++E+ TP +      GG    P 
Sbjct: 165 KYRQRYVDLIANEESRNTFIKRSQIIQSVRNFMVGEHYLEVETPMM--HPIPGGATAKPF 222

Query: 179 KYFEN----DAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEM 234
               N      +L  +P+LY + ++  GL++VFEI   FR  E  + RH  E   I+   
Sbjct: 223 VTHHNALDIPLYLRIAPELYLKRLVVGGLERVFEINRSFR-NEGMSVRHNPEFTMIEFYE 281

Query: 235 AFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALE---- 290
           AF + E  +M + E +I      V           E +L   + PF R+T  EA++    
Sbjct: 282 AFSDYER-MMQMAEDIIRNASRTVNGTANITYNGKEVDL---ESPFERLTILEAIKKYNP 337

Query: 291 -ILSDLGKEIPW-GEDIDTEGEKL-----LGKYML-------ENEGAELYFIYRYPSEAK 336
               +   +  W  ++I   GE L     +G   L       E +     FI  YP E  
Sbjct: 338 HYTDEQLNDAEWLKKEIVKHGESLPPSPGIGSLQLALFEGCAEGKLWNPTFIVDYPVEVS 397

Query: 337 PFYIMKYEDKPEVCKAFDLEYRGVEISSG----GQREHRHDILVEQIREKGL-NPESFEF 391
           P      + K  + + F+L   G E+++G       E + +    Q+ +K   + E+  +
Sbjct: 398 PL-ARASDTKQGLTERFELFVVGRELANGYSELNDPEDQAERFKAQVVQKDAGDDEAMHY 456

Query: 392 ---YLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDR 433
              Y+RA E+G+PP GG G+G +RL+M + D   IR+VILFP+ R
Sbjct: 457 DADYIRAMEFGLPPTGGCGIGIDRLVMLLTDSQTIRDVILFPQMR 501


>sp|P21889|SYD_ECOLI ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
           >gi|68534|pir||SYECD aspartate--tRNA ligase (EC
           6.1.1.12) - Escherichia coli >gi|9256904|pdb|1EQR|A
           Chain A, Crystal Structure Of Free Aspartyl-Trna
           Synthetase From Escherichia Coli >gi|9256905|pdb|1EQR|B
           Chain B, Crystal Structure Of Free Aspartyl-Trna
           Synthetase From Escherichia Coli >gi|9256906|pdb|1EQR|C
           Chain C, Crystal Structure Of Free Aspartyl-Trna
           Synthetase From Escherichia Coli
           >gi|41015|emb|CAA37856.1| (X53863) aspartate-tRNA ligase
           [Escherichia coli] >gi|1736513|dbj|BAA15677.1| (D90829)
           Aspartate--tRNA ligase (EC 6.1.1.12) [Escherichia coli]
           >gi|1788173|gb|AAC74936.1| (AE000280) aspartate tRNA
           synthetase [Escherichia coli K12]
           Length = 590
           
 Score =  122 bits (304), Expect = 6e-27
 Identities = 85/258 (32%), Positives = 134/258 (50%), Gaps = 15/258 (5%)

Query: 2   LRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFK 61
           +RT Y  ++     G++V + GWV   +DLG + FI +RDREGIVQV     +   +  K
Sbjct: 1   MRTEYCGQLRLSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGIVQVFFDPDRA--DALK 58

Query: 62  LIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKT------PLPLDPTGKVKA 115
           L  +L +E  I V G V    +  +  ++   ++EV++ + T       LPLD +  V  
Sbjct: 59  LASELRNEFCIQVTGTVRARDEKNINRDMATGEIEVLASSLTIINRADVLPLD-SNHVNT 117

Query: 116 ELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTE- 174
           E + RL  R++DLR P +    K R+ +    R F    GF++I TP +     EG  + 
Sbjct: 118 E-EARLKYRYLDLRRPEMAQRLKTRAKITSLVRRFMDDHGFLDIETPMLTKATPEGARDY 176

Query: 175 LFPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAE 233
           L P +  +   + L QSPQL+KQ++M +G D+ ++I   FR E+    R   E   ID E
Sbjct: 177 LVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQ-PEFTQIDVE 235

Query: 234 MAFIESEE--EVMDLLER 249
            +F+ + +  EVM+ L R
Sbjct: 236 TSFMTAPQVREVMEALVR 253


>sp|O83950|SYD_TREPA ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
           >gi|7437587|pir||A71256 aspartate--tRNA ligase (EC
           6.1.1.12) - syphilis spirochete
           >gi|3323310|gb|AAC65942.1| (AE001266) aspartyl-tRNA
           synthetase (aspS) [Treponema pallidum]
           Length = 602
           
 Score =  122 bits (304), Expect = 6e-27
 Identities = 90/283 (31%), Positives = 141/283 (49%), Gaps = 24/283 (8%)

Query: 16  GKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVE 75
           G  V + GWV   +  G + F  +RDR GIVQV   +++    ++  + ++  E  + VE
Sbjct: 32  GTVVVLNGWVHRKRSHGTVSFFNMRDRSGIVQVIVSQEE-NASLWSTVNRIRLECCLAVE 90

Query: 76  GIVNFTPKAKLGFEIIPEKLEVISKA------KTPLPLDPTGKVKAELDTRLDNRFMDLR 129
           G+V   P + +   +   ++EV ++          LP      V A  D RL  R++DLR
Sbjct: 91  GVVRERPPSMINRALHTGEVEVHARTLYVLSENAVLPFRVDDVVHAHEDIRLKYRYLDLR 150

Query: 130 NPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTE-LFPLKYFENDAF-L 187
           + R+     +RS V  A R+F   +GFIEI TP  I +  EG  + + P +      + L
Sbjct: 151 SQRMQERIALRSRVALAIRQFLSMKGFIEIETPTFICSTPEGARDFVVPSRVCPGRFYAL 210

Query: 188 AQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLL 247
            QSPQLYKQ++M  G D+ F++   +R E+    R   E   ID EM+F+ S ++VM + 
Sbjct: 211 PQSPQLYKQLLMVAGFDRYFQLARCYRDEDARGDRQ-PEFTQIDLEMSFV-SRDDVMRVN 268

Query: 248 ERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALE 290
           E ++ YV    R +   EL             FPR+TY +AL+
Sbjct: 269 EDMLRYVF---RTSIGVELPTF----------FPRLTYAQALD 298


>pdb|1C0A|A Chain A, Crystal Structure Of The E. Coli Aspartyl-Trna Synthetase
           : Trnaasp : Aspartyl-Adenylate Complex
           Length = 585
           
 Score =  122 bits (304), Expect = 6e-27
 Identities = 85/258 (32%), Positives = 134/258 (50%), Gaps = 15/258 (5%)

Query: 2   LRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFK 61
           +RT Y  ++     G++V + GWV   +DLG + FI +RDREGIVQV     +   +  K
Sbjct: 1   MRTEYCGQLRLSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGIVQVFFDPDRA--DALK 58

Query: 62  LIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKT------PLPLDPTGKVKA 115
           L  +L +E  I V G V    +  +  ++   ++EV++ + T       LPLD +  V  
Sbjct: 59  LASELRNEFCIQVTGTVRARDEKNINRDMATGEIEVLASSLTIINRADVLPLD-SNHVNT 117

Query: 116 ELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTE- 174
           E + RL  R++DLR P +    K R+ +    R F    GF++I TP +     EG  + 
Sbjct: 118 E-EARLKYRYLDLRRPEMAQRLKTRAKITSLVRRFMDDHGFLDIETPMLTKATPEGARDY 176

Query: 175 LFPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAE 233
           L P +  +   + L QSPQL+KQ++M +G D+ ++I   FR E+    R   E   ID E
Sbjct: 177 LVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQ-PEFTQIDVE 235

Query: 234 MAFIESEE--EVMDLLER 249
            +F+ + +  EVM+ L R
Sbjct: 236 TSFMTAPQVREVMEALVR 253


>sp|P57401|SYD_BUCAI ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
           >gi|10038990|dbj|BAB13024.1| (AP001119) aspartyl-tRNA
           synthetase [Buchnera sp. APS]
           Length = 586
           
 Score =  122 bits (304), Expect = 6e-27
 Identities = 97/298 (32%), Positives = 159/298 (52%), Gaps = 30/298 (10%)

Query: 2   LRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFK 61
           +RT Y   I      KKVK+ GWV +V++LG   F+ +RD  G+VQV    K    +IFK
Sbjct: 1   MRTKYCGNIRISHVNKKVKLCGWVHKVRNLGQFIFVDMRDYTGLVQVIFELKN--YKIFK 58

Query: 62  LIPKLNSEDVIVVEGIV------NFTPKAKLG-FEIIPEKLEVISKAKTPLPLDPTGKVK 114
               L +E  I V G V      N   K + G  EI+   L +++ +K+ LPL+ T +  
Sbjct: 59  KALNLRNEFCIQVFGTVQKREKKNQNIKIRTGEIEILANVLNILNTSKS-LPLNFTQENN 117

Query: 115 AELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTE 174
              D+RL  R++DLR+  ++   KIR+ +    R F  K+ F++I TP +  +  EG  +
Sbjct: 118 D--DSRLKYRYLDLRSFDILENLKIRNKITYLIRNFMTKKNFLDIETPILTKSTPEGARD 175

Query: 175 -LFPLK-YFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDA 232
            L P + ++     L QSPQL+KQ++M +G+D+ ++I   FR E+  + R   E   ID 
Sbjct: 176 YLVPSRNHYGKFYALPQSPQLFKQILMISGIDRYYQIVKCFRDEDLRSDRQ-PEFTQIDI 234

Query: 233 EMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALE 290
           E++F+ S +++ +L+E LI  +   +R  N K+              FP+I++ EA++
Sbjct: 235 EVSFM-SAKKIRNLVENLIKKLWLEIRNINLKK--------------FPQISFHEAMK 277


>sp|Q50649|SYD_MYCTU ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
           >gi|7437588|pir||C70724 aspartate--tRNA ligase (EC
           6.1.1.12) - Mycobacterium tuberculosis (strain H37RV)
           >gi|1478240|emb|CAB01271.1| (Z77724) aspS [Mycobacterium
           tuberculosis]
           Length = 596
           
 Score =  121 bits (301), Expect = 1e-26
 Identities = 94/306 (30%), Positives = 146/306 (46%), Gaps = 45/306 (14%)

Query: 1   MLRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF 60
           +LR+H +  + E   G++V +AGWV   +D GG+ FI +RD  GI QV   +     E+ 
Sbjct: 3   VLRSHAAGLLREGDAGQQVTLAGWVARRRDHGGVIFIDLRDASGIAQVVF-RDPQDTEVL 61

Query: 61  KLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKT------PLPL---DPTG 111
               +L +E  + V G+V   P+     EI   ++EV + + T      PLP    +P G
Sbjct: 62  AQAHRLRAEFCVSVAGVVEIRPEGNANPEIATGEIEVNATSLTVLGECAPLPFQLDEPAG 121

Query: 112 KVKAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEG 171
           +     + RL  R++DLR     +  ++RS V  A R    +  F+EI TP I  +  EG
Sbjct: 122 E-----ELRLKYRYLDLRRDDPAAAIRLRSRVNAAARAVLARHDFVEIETPTITRSTPEG 176

Query: 172 GTE-LFPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWS 229
             + L P +      + L QSPQL+KQ++M  G+++ ++I   +R E+    R   E   
Sbjct: 177 ARDFLVPARLHPGSFYALPQSPQLFKQLLMVAGMERYYQIARCYRDEDFRADRQ-PEFTQ 235

Query: 230 IDAEMAFIESE------EEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRI 283
           +D EM+F+++E      EEV+  L  LI Y I                       P PRI
Sbjct: 236 LDMEMSFVDAEDIIAISEEVLTELWALIGYRI---------------------PTPIPRI 274

Query: 284 TYDEAL 289
            Y EA+
Sbjct: 275 GYAEAM 280


>sp|Q9Z7P2|SYD_CHLPN ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
           >gi|7437604|pir||G72052 aspartate--tRNA ligase (EC
           6.1.1.12) - Chlamydophila pneumoniae (strains CWL029 and
           AR39) >gi|4376961|gb|AAD18801.1| (AE001648) Aspartyl
           tRNA Synthetase [Chlamydophila pneumoniae CWL029]
           >gi|7189021|gb|AAF37971.1| (AE002172) aspartyl-tRNA
           synthetase [Chlamydophila pneumoniae AR39]
           >gi|8979034|dbj|BAA98869.1| (AP002547) aspartyl tRNA
           synthetase [Chlamydophila pneumoniae J138]
           Length = 584
           
 Score =  120 bits (298), Expect = 3e-26
 Identities = 93/309 (30%), Positives = 155/309 (50%), Gaps = 20/309 (6%)

Query: 3   RTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKL 62
           RTH  +E+T    G+ V++AGWV   ++ GG+ FI +RDR GI Q+   + + P E+ + 
Sbjct: 4   RTHRCNELTSNHIGENVQLAGWVHRYRNHGGVVFIDLRDRFGITQIVCREDEQP-ELHQR 62

Query: 63  IPKLNSEDVIVVEGIV------NFTPKAKLG-FEIIPEKLEVISKAKTPLPLD-PTGKVK 114
           +  + SE V+ V G V         P    G  E+     EV+SK++  LP       + 
Sbjct: 63  LDAVRSEWVLSVRGKVCPRLAGMENPNLATGHIEVEVASFEVLSKSQN-LPFSIADDHIN 121

Query: 115 AELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTE 174
              + RL+ R++D+R   ++     R  V  A R F   +GF EI TP +  +  EG  +
Sbjct: 122 VNEELRLEYRYLDMRRGDIIEKLLCRHQVMLACRNFMDAQGFTEIVTPVLGKSTPEGARD 181

Query: 175 -LFPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDA 232
            L P + +    + L QSPQL+KQ++M  GLD+ F+I   FR E+    R   E   ID 
Sbjct: 182 YLVPSRIYPGKFYALPQSPQLFKQLLMVGGLDRYFQIATCFRDEDLRADRQ-PEFAQIDI 240

Query: 233 EMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPF----PRITYDEA 288
           EM+F ++ ++++ ++E+L+  +  +  +  E  L + +    E K  +    P + +D  
Sbjct: 241 EMSFGDT-QDLLPIIEQLVATL--FATQGIEIPLPLAKMTYQEAKDSYGTDKPDLRFDLK 297

Query: 289 LEILSDLGK 297
           L+   D  K
Sbjct: 298 LKDCRDYAK 306


>sp|O51402|SYD_BORBU ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
           Length = 586
           
 Score =  120 bits (297), Expect = 4e-26
 Identities = 85/298 (28%), Positives = 144/298 (47%), Gaps = 29/298 (9%)

Query: 1   MLRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF 60
           M +    +E+ E+L  KKV++  WV++++  G   F+ IRDR    QV   ++K    + 
Sbjct: 1   MFKVIKCNELNEKLIDKKVEINAWVKKIRHHGKFIFLNIRDRYEKAQVLVNEEK----LL 56

Query: 61  KLIPKLNSEDVIVVEGIVNFTPKAKLG-------FEIIPEKLEVISKAKTPLPLDPTGKV 113
           K+  K+  E  I ++G++   P   +        FEI+ + +E+ISK    LP       
Sbjct: 57  KIAEKIKLEYCIKIQGLLIKRPPNMINANMKTGHFEILAKNIEIISKCNE-LPFMIEDDN 115

Query: 114 KAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGT 173
            A  +++L+ R++DLR   + +   +R       R F  K  F+E+ TP  + +  EG  
Sbjct: 116 NASENSKLEYRYLDLRRDSLKNKIILRCQATHLIRNFLIKRKFLELETPTFVKSTPEGAR 175

Query: 174 ELFPLKYFENDAFLA--QSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSID 231
           +          +F A  QSPQLYKQ++M  G DK F+I   +R E+    R   E   +D
Sbjct: 176 DFVIPSRIHKGSFYALPQSPQLYKQLIMIAGFDKYFQIARCYRDEDSRGDRQ-PEFTQLD 234

Query: 232 AEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEAL 289
            EM+F++ +E +  L+E ++  +                  +N PKK F +ITY +A+
Sbjct: 235 LEMSFVK-KENIFKLIENMLFLIFKNC------------ININLPKK-FKKITYKKAM 278


 Score = 69.1 bits (166), Expect = 1e-10
 Identities = 39/103 (37%), Positives = 56/103 (53%), Gaps = 6/103 (5%)

Query: 336 KPFYIMKYEDKPE--VCKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPES----F 389
           K  YI   E  P+  + + +DL   GVE+ SG  R H  ++     +  G   E     F
Sbjct: 453 KKQYIANLEKNPKKTIGEIYDLVLNGVELGSGSIRIHNKELQQRIFKIIGFQKEKSEDRF 512

Query: 390 EFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRD 432
            F+L+A EYG P HGG  +G +RLIM M    +I++VILFP++
Sbjct: 513 GFFLKALEYGAPNHGGIAIGIDRLIMLMTKSTSIKDVILFPKN 555


>sp|Q9PEB6|SYK_XYLFA LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
           >gi|11271299|pir||E82721 lysyl-tRNA synthetase XF1112
           [imported] - Xylella fastidiosa (strain 9a5c)
           >gi|9106069|gb|AAF83922.1|AE003947_2 (AE003947)
           lysyl-tRNA synthetase [Xylella fastidiosa]
           Length = 506
           
 Score =  119 bits (295), Expect = 7e-26
 Identities = 123/452 (27%), Positives = 203/452 (44%), Gaps = 49/452 (10%)

Query: 13  ELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVI 72
           E +G +V++AG +   + +G   F  I+D  G +Q+      + ++ +     L+  D+I
Sbjct: 64  EASGDRVRMAGRLMAKRLMGKASFAQIQDESGRIQLLIQSNVLGEDSYAAFKVLDVGDII 123

Query: 73  VVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDL-RNP 131
            VEG +  T   +L  ++    L +++KA  PLP    G    +++ R   R++DL   P
Sbjct: 124 AVEGGLTRTRTGELSVKV--NVLRLLTKALRPLPDKWHG--LTDVEQRYRQRYVDLIVTP 179

Query: 132 RVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFEN----DAFL 187
               IF  RS + RA R +     F+E+ TP  +     GG    P   + N    + +L
Sbjct: 180 ESREIFIKRSKIIRALRTWLDARLFLEVETP--MMHYIPGGAAAKPFVTYHNALDLELYL 237

Query: 188 AQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLL 247
             +P+LY + ++  GL++V+EI   FR  E  +TRH  E   ++   A+  +  EVMDL 
Sbjct: 238 RVAPELYLKRLVVGGLERVYEINRNFR-NEGVSTRHNPEFTMLELYEAY-STYHEVMDLA 295

Query: 248 ERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIPWGEDIDT 307
           E +I      V    +      + +L      F R   DEA   +     EI   E  D 
Sbjct: 296 ETMIRDTAQSVLGTTQVIWDGAQIDLG---PIFRRWRMDEA---VCHHNPEISVAECTDR 349

Query: 308 E-------------------GEKLLGKY--MLENEGAELYFIYRYPSEAKPFYIMKYEDK 346
           +                   G  LL  +   +E+   +  FI  +P E  P    + + +
Sbjct: 350 DALLLHCERLKIKVKSSYGWGRLLLSIFEATVEHTLIQPTFITDHPVEISPL-ARESDIE 408

Query: 347 PEVCKAFDLEYRGVEISSG----GQREHRHDILVEQIREK-GLNPESFEF---YLRAFEY 398
           P     F+L   G EI++G       E +     +Q+  K G + E+  +   Y+RA EY
Sbjct: 409 PGYTDRFELFINGKEIANGFSELNDPEEQAMRFQKQVEAKEGGDDEAMYYDADYIRALEY 468

Query: 399 GMPPHGGFGLGAERLIMRMLDIGNIREVILFP 430
           GM P GG G+G +RL+M +    +IR+V+LFP
Sbjct: 469 GMAPTGGLGIGVDRLVMLLTGSTSIRDVLLFP 500


>gb|AAA24096.1| (M30630) lysyl-tRNA synthetase (lysU) (E.C. 6.1.1.6) [Escherichia
           coli]
           Length = 501
           
 Score =  118 bits (293), Expect = 1e-25
 Identities = 119/472 (25%), Positives = 197/472 (41%), Gaps = 56/472 (11%)

Query: 3   RTHYSSEITEELNGK----------KVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPK 52
           R H S ++ EE + K          +V VAG +   + +G   F+ ++D  G +Q+   +
Sbjct: 42  RDHTSDQLHEEFDAKDNQELESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVAR 101

Query: 53  KKVPQEIFKLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGK 112
             +P+ ++    K      I+  G +  T   +L       +L +++KA  PLP    G 
Sbjct: 102 DSLPEGVYNDQFKKWDLGDIIGAGTLFKTQTGELSIHCT--ELRLLTKALRPLPDKFHGL 159

Query: 113 VKAELDTRLDNRFMDL-RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEG 171
              E+  R   R++DL  N +    F +RS +  A R+F    GF+E+ TP +      G
Sbjct: 160 QDQEV--RYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMM--QVIPG 215

Query: 172 GTELFPLKYFEN----DAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEA 227
           G    P     N    D +   +P+LY + ++  G ++VFE             RH  E 
Sbjct: 216 GASARPFITHHNALDLDMYARIAPELYLKRLVVGGFERVFE----HVTRNEGIRRHNPEF 271

Query: 228 WSIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDE 287
             ++  MA+ +  + +++L E L   +   V    +       F+     KPF ++T  E
Sbjct: 272 TMMELYMAYADYHD-LIELTESLFRTLAQEVLGTTKVTYGEHVFDFG---KPFEKLTMRE 327

Query: 288 ALEI---------LSDLGKEIPWGEDIDTEGEKLLG---------KYMLENEGAELYFIY 329
           A++          L +        E I    EK  G           ++E    +  FI 
Sbjct: 328 AIKKYRPETDMADLDNFDARKALAESIGITVEKSWGLGRSVTEIFDEVVEGHVIQPSFIT 387

Query: 330 RYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSG----GQREHRHDILVEQIREKGLN 385
            YP+E  P    + +  PE+   F+    G EI +G       E + +   EQ+  K   
Sbjct: 388 EYPAEVSPL-ARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAG 446

Query: 386 PESFEFY----LRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDR 433
            +   FY    + A EYG+PP  G G+G +R+IM   +   IR+VILFP  R
Sbjct: 447 DDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMIMLFTNSHTIRDVILFPAMR 498


>sp|P36429|SYD_MYCLE ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS) (ANTIGEN
           T5) >gi|541455|pir||S42047 aspartate--tRNA ligase (EC
           6.1.1.12) - Mycobacterium leprae
           >gi|581332|emb|CAA54735.1| (X77655) aspartyl-tRNA
           synthetase [Mycobacterium leprae]
           >gi|3136016|emb|CAA19094.1| (AL023591) aspartyl-tRNA
           synthetase [Mycobacterium leprae]
           >gi|3335328|gb|AAC27132.1|S82268_1 (S82268)
           aspartyl-tRNA synthetase [Mycobacterium leprae]
           Length = 589
           
 Score =  118 bits (292), Expect = 2e-25
 Identities = 90/306 (29%), Positives = 141/306 (45%), Gaps = 48/306 (15%)

Query: 1   MLRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF 60
           MLR+H +  + +   G++V +AGWV   +D GG+ FI +RD  GI Q    +     ++ 
Sbjct: 1   MLRSHGAGVLRKSDAGQQVTLAGWVSRRRDHGGVIFIDLRDSSGITQAVFRE----PDVL 56

Query: 61  KLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKT------PLPL---DPTG 111
               +L +E  I V G+V   P+     EI    +EV + + T      PLP    +P G
Sbjct: 57  AQAHRLRAEFCIAVSGVVEIRPEGNANAEIPTGDIEVNATSLTVLGESAPLPFQLDEPAG 116

Query: 112 KVKAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEG 171
           +     + RL  R++DLR     S  ++RS V    R    +  F+EI TP I  +  EG
Sbjct: 117 E-----ELRLKYRYLDLRRDGPGSAIRLRSKVNATARAVLARHDFVEIETPTITRSTPEG 171

Query: 172 GTELFPLKYFENDAF--LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWS 229
             +           F  L QSPQL+KQ++M  G+++ ++I   +R E+    R   E   
Sbjct: 172 ARDFLVPARLRPGTFYALPQSPQLFKQLLMVAGMERYYQIAHCYRDEDFRADRQ-PEFTQ 230

Query: 230 IDAEMAFIESE------EEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRI 283
           +D EM+F+++E      EE++  L  LI Y I                       P PRI
Sbjct: 231 LDMEMSFVDAEDVIAISEEILTELWMLIGYHI---------------------PAPIPRI 269

Query: 284 TYDEAL 289
           +Y +A+
Sbjct: 270 SYADAM 275


>pir||S69892 lysine--tRNA ligase (EC 6.1.1.6) - Mycoplasma hominis
           Length = 488
           
 Score =  116 bits (289), Expect = 4e-25
 Identities = 115/429 (26%), Positives = 200/429 (45%), Gaps = 50/429 (11%)

Query: 36  FIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKL 95
           FI ++D  G +Q+ A KK + +   K    ++  D++ V G ++ T    L   I  + +
Sbjct: 72  FIVLQDNCGQMQIYANKKTLNESSAKTFSLMDFGDILSVRGTLSKTNTDAL--VIKAQDI 129

Query: 96  EVISKAKTPLPLDPTGKVKAELDTRLDNRFMDL-RNPRVMSIFKIRSSVFRATREFFYKE 154
            +++K+  PLP    G V  E   R   R++DL  N +  + F +R+ + +  RE+F   
Sbjct: 130 VLLTKSLKPLPDKFHGLVDPE--ERRRQRYVDLIMNEKTRNTFVMRTQIIKGIREYFDSL 187

Query: 155 GFIEIHTPKIIATATEGGTELFPLKYFEN----DAFLAQSPQLYKQMMMSTGLDKVFEIG 210
            +IE+ TP  I     GG    P   F N    + +L  + +L  + ++  GLD+V+EIG
Sbjct: 188 NYIEVDTP--ILNPILGGAAAKPFITFYNALNRNFYLRIATELPLKKLIVGGLDRVYEIG 245

Query: 211 PIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILE 270
            IFR E  +TT H  E  SI+    F E+  ++  ++ER      + + + N KE+K   
Sbjct: 246 RIFRNEGVDTT-HNPEFTSIE----FYEAYSDLWGMMERTEGVFKHLINKFNIKEVKFNG 300

Query: 271 FELNEPKKPFPRITYDEAL-------------EILSDLGKE--------IPWGEDIDTEG 309
           F++     PF R+   +A+             E + +L K+          +G  I+   
Sbjct: 301 FDITF-NFPFKRVNMIDAISEKINVDIRKLNEEQMFELAKKHGIKIEKFFRYGHIINELF 359

Query: 310 EKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAF----DLEYRGVEISSG 365
           EK + + ++E       F+Y +P E  P   +  +DK    +A       E+  +     
Sbjct: 360 EKYVEETLIEPT-----FVYGHPIEISPLAAIDPDDKRFTLRAELFIGTKEFANMFTELN 414

Query: 366 GQREHRHDILVEQIREKGLNPESFEF---YLRAFEYGMPPHGGFGLGAERLIMRMLDIGN 422
              +       + + ++  N E+ E    ++ A EYGMPP GG G+G +RLIM +    +
Sbjct: 415 DPIDQLQRFENQLLEKENGNEEANEIDWDFVNALEYGMPPTGGSGIGIDRLIMLLTQNDS 474

Query: 423 IREVILFPR 431
           IR+V+LFP+
Sbjct: 475 IRDVVLFPQ 483


>sp|P37879|SYK_CRILO LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
           >gi|543180|pir||S43187 lysine--tRNA ligase (EC 6.1.1.6)
           - long-tailed hamster >gi|469122|emb|CAA83505.1|
           (Z31711) Lysyl tRNA Synthetase [Cricetulus
           longicaudatus]
           Length = 597
           
 Score =  116 bits (289), Expect = 4e-25
 Identities = 127/470 (27%), Positives = 207/470 (44%), Gaps = 68/470 (14%)

Query: 12  EELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGI-VQVTAPKK--KVPQEIFKLIPKLNS 68
           + L    +KVAG +   +  GG    +    EG+ +QV A  +  K  +E  ++  KL  
Sbjct: 119 DHLTDITLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFVRINNKLRR 178

Query: 69  EDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDL 128
            D+I V+G    T K +L   IIP ++ ++S     LP    G    E  TR   R++DL
Sbjct: 179 GDIIGVQGNPGKTKKGELS--IIPYEITLLSPCLHMLPHLHFGLKDKE--TRYRQRYLDL 234

Query: 129 -RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDA-- 185
             N  V   F +R+ +    R F  + GF+EI TP +      GG    P   + N+   
Sbjct: 235 ILNDFVRQKFIVRAKIITYIRSFLDELGFLEIETPMM--NIIPGGAVAKPFITYHNELDM 292

Query: 186 --FLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEV 243
             ++  +P+LY +M++  G+D+V+EIG  FR E  + T H  E  + +  MA+ +  + +
Sbjct: 293 NLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLT-HNPEFTTCEFYMAYADYHD-L 350

Query: 244 MDLLERLIL---------YVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSD 294
           M++ E+++          Y I Y  +  E E   ++F       PF RI+  E LE    
Sbjct: 351 MEITEKMLSGMVKSITGSYKITYHPDGPEGEAYEIDFT-----PPFRRISMVEELE--KA 403

Query: 295 LGKEIPWGEDIDTEG--------------------------EKLLGKYMLENEGAELYFI 328
           LG ++P     +TE                           +KL+G++ LE       FI
Sbjct: 404 LGVKLPETSLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEF-LEVTCINPTFI 462

Query: 329 YRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSG----GQREHRHDILVEQIREKGL 384
             +P    P     +  K  + + F+L     EI +          +  +  EQ + K  
Sbjct: 463 CDHPQIMSPL-AKWHRSKEGLTERFELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAA 521

Query: 385 NPESFEF----YLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFP 430
             +   F    +  A EYG+PP  G+G+G +R+ M + D  NI+EV+LFP
Sbjct: 522 GDDEAMFIDENFCTALEYGLPPTAGWGMGIDRVTMFLTDSNNIKEVLLFP 571


>dbj|BAA06688.1| (D31890) similar to lysyl tRNA synthetase. [Homo sapiens]
           Length = 601
           
 Score =  116 bits (287), Expect = 6e-25
 Identities = 127/470 (27%), Positives = 205/470 (43%), Gaps = 68/470 (14%)

Query: 12  EELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGI-VQVTAPKK--KVPQEIFKLIPKLNS 68
           + L    +KVAG +   +  GG    +    EG+ +QV A  +  K  +E   +  KL  
Sbjct: 123 DHLTDITLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFIHINNKLRR 182

Query: 69  EDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDL 128
            D+I V+G    T K +L   IIP ++ ++S     LP    G    E  TR   R++DL
Sbjct: 183 GDIIGVQGNPGKTKKGELS--IIPYEITLLSPCLHMLPHLHFGLKDKE--TRYRQRYLDL 238

Query: 129 -RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDA-- 185
             N  V   F IRS +    R F  + GF+EI TP +      GG    P   + N+   
Sbjct: 239 ILNDFVRQKFIIRSKIITYIRSFLDELGFLEIETPMM--NIIPGGAVAKPFITYHNELDM 296

Query: 186 --FLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEV 243
             ++  +P+LY +M++  G+D+V+EIG  FR E  + T H  E  + +  MA+ +  + +
Sbjct: 297 NLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLT-HNPEFTTCEFYMAYADYHD-L 354

Query: 244 MDLLERLIL---------YVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSD 294
           M++ E+++          Y + Y  +  E +   ++F       PF RI   E LE    
Sbjct: 355 MEITEKMVSGMVKHITGSYKVTYHPDGPEGQAYDVDFT-----PPFRRINMVEELE--KA 407

Query: 295 LGKEIPWGEDIDTEG--------------------------EKLLGKYMLENEGAELYFI 328
           LG ++P     +TE                           +KL+G++ LE       FI
Sbjct: 408 LGMKLPETNLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEF-LEVTCINPTFI 466

Query: 329 YRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSG----GQREHRHDILVEQIREKGL 384
             +P    P     +  K  + + F+L     EI +          +  +  EQ + K  
Sbjct: 467 CDHPQIMSPL-AKWHRSKEGLTERFELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAA 525

Query: 385 NPESFEF----YLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFP 430
             +   F    +  A EYG+PP  G+G+G +R+ M + D  NI+EV+LFP
Sbjct: 526 GDDEAMFIDENFCTALEYGLPPTAGWGMGIDRVAMFLTDSNNIKEVLLFP 575


>gi|5031815 lysyl-tRNA synthetase; lysine tRNA ligase [Homo sapiens]
           >gi|11525803|ref|XP_007820.1| lysyl-tRNA synthetase
           [Homo sapiens] >gi|2366752|dbj|BAA22084.1| (D32053)
           Lysyl tRNA Synthetase [Homo sapiens]
           Length = 597
           
 Score =  116 bits (287), Expect = 6e-25
 Identities = 127/470 (27%), Positives = 205/470 (43%), Gaps = 68/470 (14%)

Query: 12  EELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGI-VQVTAPKK--KVPQEIFKLIPKLNS 68
           + L    +KVAG +   +  GG    +    EG+ +QV A  +  K  +E   +  KL  
Sbjct: 119 DHLTDITLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFIHINNKLRR 178

Query: 69  EDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDL 128
            D+I V+G    T K +L   IIP ++ ++S     LP    G    E  TR   R++DL
Sbjct: 179 GDIIGVQGNPGKTKKGELS--IIPYEITLLSPCLHMLPHLHFGLKDKE--TRYRQRYLDL 234

Query: 129 -RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDA-- 185
             N  V   F IRS +    R F  + GF+EI TP +      GG    P   + N+   
Sbjct: 235 ILNDFVRQKFIIRSKIITYIRSFLDELGFLEIETPMM--NIIPGGAVAKPFITYHNELDM 292

Query: 186 --FLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEV 243
             ++  +P+LY +M++  G+D+V+EIG  FR E  + T H  E  + +  MA+ +  + +
Sbjct: 293 NLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLT-HNPEFTTCEFYMAYADYHD-L 350

Query: 244 MDLLERLIL---------YVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSD 294
           M++ E+++          Y + Y  +  E +   ++F       PF RI   E LE    
Sbjct: 351 MEITEKMVSGMVKHITGSYKVTYHPDGPEGQAYDVDFT-----PPFRRINMVEELE--KA 403

Query: 295 LGKEIPWGEDIDTEG--------------------------EKLLGKYMLENEGAELYFI 328
           LG ++P     +TE                           +KL+G++ LE       FI
Sbjct: 404 LGMKLPETNLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEF-LEVTCINPTFI 462

Query: 329 YRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSG----GQREHRHDILVEQIREKGL 384
             +P    P     +  K  + + F+L     EI +          +  +  EQ + K  
Sbjct: 463 CDHPQIMSPL-AKWHRSKEGLTERFELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAA 521

Query: 385 NPESFEF----YLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFP 430
             +   F    +  A EYG+PP  G+G+G +R+ M + D  NI+EV+LFP
Sbjct: 522 GDDEAMFIDENFCTALEYGLPPTAGWGMGIDRVAMFLTDSNNIKEVLLFP 571


>sp|Q15046|SYK_HUMAN LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS) (KIAA0070)
           Length = 597
           
 Score =  116 bits (287), Expect = 6e-25
 Identities = 127/470 (27%), Positives = 205/470 (43%), Gaps = 68/470 (14%)

Query: 12  EELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGI-VQVTAPKK--KVPQEIFKLIPKLNS 68
           + L    +KVAG +   +  GG    +    EG+ +QV A  +  K  +E   +  KL  
Sbjct: 119 DHLTDITLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFIHINNKLRR 178

Query: 69  EDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDL 128
            D+I V+G    T K +L   IIP ++ ++S     LP    G    E  TR   R++DL
Sbjct: 179 GDIIGVQGNPGKTKKGELS--IIPYEITLLSPCLHMLPHLHFGLKDKE--TRYRQRYLDL 234

Query: 129 -RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDA-- 185
             N  V   F IRS +    R F  + GF+EI TP +      GG    P   + N+   
Sbjct: 235 ILNDFVRQKFIIRSKIITYIRSFLDELGFLEIETPMM--NIIPGGAVAKPFITYHNELDM 292

Query: 186 --FLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEV 243
             ++  +P+LY +M++  G+D+V+EIG  FR E  + T H  E  + +  MA+ +  + +
Sbjct: 293 NLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLT-HNPEFTTCEFYMAYADYHD-L 350

Query: 244 MDLLERLIL---------YVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSD 294
           M++ E+++          Y + Y  +  E +   ++F       PF RI   E LE    
Sbjct: 351 MEITEKMVSGMVKHITGSYKVTYHPDGPEGQAYDVDFT-----PPFRRINMVEELE--KA 403

Query: 295 LGKEIPWGEDIDTEG--------------------------EKLLGKYMLENEGAELYFI 328
           LG ++P     +TE                           +KL+G++ LE       FI
Sbjct: 404 LGMKLPETNLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEF-LEVTCINPTFI 462

Query: 329 YRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSG----GQREHRHDILVEQIREKGL 384
             +P    P     +  K  + + F+L     EI +          +  +  EQ + K  
Sbjct: 463 CDHPQIMSPL-AKWHRSKEGLTERFELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAA 521

Query: 385 NPESFEF----YLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFP 430
             +   F    +  A EYG+PP  G+G+G +R+ M + D  NI+EV+LFP
Sbjct: 522 GDDEAMFIDENFCTALEYGLPPTAGWGMGIDRVAMFLTDSNNIKEVLLFP 571


>gb|AAG30114.1|AF285758_1 (AF285758) lysyl-tRNA synthetase [Homo sapiens]
           Length = 625
           
 Score =  116 bits (287), Expect = 6e-25
 Identities = 127/470 (27%), Positives = 205/470 (43%), Gaps = 68/470 (14%)

Query: 12  EELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGI-VQVTAPKK--KVPQEIFKLIPKLNS 68
           + L    +KVAG +   +  GG    +    EG+ +QV A  +  K  +E   +  KL  
Sbjct: 147 DHLTDITLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFIHINNKLRR 206

Query: 69  EDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDL 128
            D+I V+G    T K +L   IIP ++ ++S     LP    G    E  TR   R++DL
Sbjct: 207 GDIIGVQGNPGKTKKGELS--IIPYEITLLSPCLHMLPHLHFGLKDKE--TRYRQRYLDL 262

Query: 129 -RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDA-- 185
             N  V   F IRS +    R F  + GF+EI TP +      GG    P   + N+   
Sbjct: 263 ILNDFVRQKFIIRSKIITYIRSFLDELGFLEIETPMM--NIIPGGAVAKPFITYHNELDM 320

Query: 186 --FLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEV 243
             ++  +P+LY +M++  G+D+V+EIG  FR E  + T H  E  + +  MA+ +  + +
Sbjct: 321 NLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLT-HNPEFTTCEFYMAYADYHD-L 378

Query: 244 MDLLERLIL---------YVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSD 294
           M++ E+++          Y + Y  +  E +   ++F       PF RI   E LE    
Sbjct: 379 MEITEKMVSGMVKHITGSYKVTYHPDGPEGQAYDVDFT-----PPFRRINMVEELE--KA 431

Query: 295 LGKEIPWGEDIDTEG--------------------------EKLLGKYMLENEGAELYFI 328
           LG ++P     +TE                           +KL+G++ LE       FI
Sbjct: 432 LGMKLPETNLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEF-LEVTCINPTFI 490

Query: 329 YRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSG----GQREHRHDILVEQIREKGL 384
             +P    P     +  K  + + F+L     EI +          +  +  EQ + K  
Sbjct: 491 CDHPQIMSPL-AKWHRSKEGLTERFELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAA 549

Query: 385 NPESFEF----YLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFP 430
             +   F    +  A EYG+PP  G+G+G +R+ M + D  NI+EV+LFP
Sbjct: 550 GDDEAMFIDENFCTALEYGLPPTAGWGMGIDRVAMFLTDSNNIKEVLLFP 599


>sp|P81432|SYD_BUCAP ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
           >gi|2947034|gb|AAC05432.1| (L43549) aspartyl-tRNA
           synthetase [Buchnera aphidicola]
           Length = 584
           
 Score =  115 bits (286), Expect = 8e-25
 Identities = 91/296 (30%), Positives = 152/296 (50%), Gaps = 28/296 (9%)

Query: 2   LRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFK 61
           +RT Y   I      K V + GWV ++++     FI +RD  GIVQ+   KK    ++F 
Sbjct: 1   MRTKYCGNIRIIDLHKSVILCGWVHKIRNFSQFIFIDMRDWTGIVQLVFEKKN--NKVFT 58

Query: 62  LIPKLNSEDVIVVEGIV-----NFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAE 116
               L +E  I V GIV     N         EI+  K++V + +K  LPLD +    + 
Sbjct: 59  KAVNLKNESCIQVIGIVKKRNANNNNLDTGEIEILVNKIKVFNISKN-LPLDYSNN--SN 115

Query: 117 LDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTE-L 175
            D RL  R++DLR   ++   KIR+ +    R F   + F++I TP +  +  EG  + L
Sbjct: 116 DDIRLKYRYLDLRRSELLENLKIRNKITHLIRIFMENKNFLDIETPFLTKSTPEGARDYL 175

Query: 176 FPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEM 234
            P + +  + + L QSPQL+KQ++M +G+DK ++I   FR E+  + R   E   ID E 
Sbjct: 176 VPSRNYPGNFYALPQSPQLFKQILMISGIDKYYQIVKCFRDEDLRSDRQ-PEFTQIDIEA 234

Query: 235 AFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALE 290
           +F+ S  ++ +L+E LI  +           LK++ + LN+    FP+I++ ++++
Sbjct: 235 SFV-SSTKIRNLVETLIKKI----------WLKVINYNLNK----FPKISFYDSMK 275


>sp|Q22099|SYK_CAEEL PROBABLE LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
           >gi|7437595|pir||T16780 hypothetical protein T02G5.9 -
           Caenorhabditis elegans >gi|1086773|gb|AAA82396.1|
           (U41105) coded for by C. elegans cDNA yk124d11.3; coded
           for by C. elegans cDNA yk48a4.3; coded for by C. elegans
           cDNA yk124d11.5; coded for by C. elegans cDNA cm7h5;
           coded for by C. elegans cDNA cm7a10;  similar to class
           II aminoacyl-tRNA synthetases [>
           Length = 572
           
 Score =  114 bits (282), Expect = 2e-24
 Identities = 125/479 (26%), Positives = 208/479 (43%), Gaps = 63/479 (13%)

Query: 4   THYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGI-VQVTAPKKKVPQEI--F 60
           T Y+    E++  + V VAG +   ++ G     +    EG  +Q+ A  K    ++   
Sbjct: 90  TKYTPLEKEQVVEEIVSVAGRIHSKRESGSKLVFYDIHGEGTHIQIMANAKFHTGDVDFV 149

Query: 61  KLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTR 120
            L  ++   D++   G    T   +L   +IP ++  ++     LP    G    EL  R
Sbjct: 150 TLHDRIKRGDIVGFTGRATRTKAGELS--LIPNEILQLTPCLHMLPHSHFGLKDKEL--R 205

Query: 121 LDNRFMDL-RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLK 179
              R++DL  NPRV   F IRS +    R +    GF+E+ TP  I     GG    P  
Sbjct: 206 FRKRYLDLILNPRVKDNFVIRSKIITFLRRYLDNLGFLEVETP--IMNQIAGGATAKPFI 263

Query: 180 YFENDA----FLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMA 235
              ND     FL  +P+LY +M++  G+D+V+E+G +FR E  + T H  E  + +  MA
Sbjct: 264 THHNDLDMNLFLRVAPELYHKMLVVGGIDRVYEVGRLFRNEGIDLT-HNPEFTTCEFYMA 322

Query: 236 FIESEEEVM---DLLERLIL-----YVINYVRENNEKELKILEFELNEPKK--------- 278
           + + E+ +    DLL  +++     Y I Y   N      + E +   P K         
Sbjct: 323 YADYEDVIQLTEDLLSSMVMSIKGTYKIEY-HPNGPNTEPVYEVDFTPPFKRVHMYDGLA 381

Query: 279 -------PFPRITY-DEALEILSDLGKEIPWGEDIDTEG--------EKLLGKYMLENEG 322
                  P P   + +EA E+   L ++     ++D           +KL+G+Y LE+  
Sbjct: 382 EKLGATLPDPSTLHTEEAREVFDKLCRD----NNVDCSAPRTTARLLDKLVGEY-LESTF 436

Query: 323 AELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSGGQREH----RHDILVEQ 378
               F+  +P    P     +   P + + F+L     EI++     +    +     +Q
Sbjct: 437 ISPTFLIGHPQIMSPL-AKWHRSIPGLTERFELFAVTREIANAYTELNDPITQRQRFEQQ 495

Query: 379 IREKGLNPESF----EFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDR 433
            ++K    +      E +  A EYG+PP GG+G+G +RL M + D  NI+EV+LFP  R
Sbjct: 496 AKDKDAGDDEAQMIDETFCNALEYGLPPTGGWGMGIDRLSMILTDNNNIKEVLLFPAMR 554


>emb|CAA39699.1| (X56259) lysine--tRNA ligase [Saccharomyces cerevisiae]
           Length = 591
           
 Score =  114 bits (282), Expect = 2e-24
 Identities = 127/474 (26%), Positives = 208/474 (43%), Gaps = 71/474 (14%)

Query: 12  EELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGI-VQVTAPKKKV--PQEIFKLIPKLNS 68
           E L  +KV +AG +   ++ G     ++   +G+ VQ+ +  +    P+   K    L  
Sbjct: 117 ETLPEEKVSIAGRIHAKRESGSKLKFYVLHGDGVEVQLMSQLQDYHDPESYEKDHDLLKR 176

Query: 69  EDVIVVEGIVNFTPKAKLG---FEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRF 125
            D++ VEG V  T   K G     +   ++++++     LP D  G    E  TR   R+
Sbjct: 177 GDIVGVEGYVGRTQPKKGGEGEVSVFVSRVQLLTPCLHMLPADHFGFKDQE--TRYRKRY 234

Query: 126 MDL-RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFEND 184
           +DL  N    + F  RS + R  R+F  +  FIE+ TP +   A  GG    P     ND
Sbjct: 235 LDLIMNKDARNRFITRSEIIRYIRKFLDQRKFIEVETPMMNVIA--GGATAKPFITHHND 292

Query: 185 A----FLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESE 240
                ++  +P+L+ + ++  GLD+V+EIG  FR E  + T H  E  + +    F ++ 
Sbjct: 293 LDMDMYMRIAPELFLKQLVVGGLDRVYEIGRQFRNEGIDMT-HNPEFTTCE----FYQAY 347

Query: 241 EEVMDLLERLILYVINYVRENNEKEL---------KILEFELNEPKKPFPRITYDEALEI 291
            +V DL++   L     V+E     +            E ELN   +P+ RI   E LE 
Sbjct: 348 ADVYDLMDMTELMFSEMVKEITGSYIIKYHPDPADPAKELELNF-SRPWKRINMIEELEK 406

Query: 292 LSDLGKEIPWGEDIDTEG--------------------------EKLLGKYMLENEGAEL 325
           + ++  + P G+ + T                            +KL+G+  LE+     
Sbjct: 407 VFNV--KFPSGDQLHTAETGEFLKKVLADNKLECPPPLTNARMLDKLVGE--LEDTCINP 462

Query: 326 YFIYRYPSEAKPFYIMKYE-DKPEVCKAFDLEYRGVEISSGGQREH----RHDILVEQIR 380
            FI+ +P    P  + KY  D+P +C+ F++     EI +     +    +     EQ R
Sbjct: 463 TFIFGHPQMMSP--LAKYSRDQPGLCERFEVFVATKEICNAYTELNDPFDQRARFEEQAR 520

Query: 381 EKGLNPESF----EFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFP 430
           +K    +      E +  A EYG+PP GG+G G +RL M + D   IREV+LFP
Sbjct: 521 QKDQGDDEAQLVDETFCNALEYGLPPTGGWGCGIDRLAMFLTDSNTIREVLLFP 574


>gi|6320242 lysyl-tRNA synthetase; Krs1p [Saccharomyces cerevisiae]
           >gi|135139|sp|P15180|SYKC_YEAST LYSYL-TRNA SYNTHETASE,
           CYTOPLASMIC (LYSINE--TRNA LIGASE) (LYSRS)
           >gi|68528|pir||SYBYKT lysine--tRNA ligase (EC 6.1.1.6) -
           yeast (Saccharomyces cerevisiae)
           >gi|171799|gb|AAA66916.1| (J04186) lysyl-tRNA synthetase
           [Saccharomyces cerevisiae] >gi|1122359|emb|CAA92376.1|
           (Z68196) Krs1p [Saccharomyces cerevisiae]
           >gi|1431484|emb|CAA98863.1| (Z74333) ORF YDR037w
           [Saccharomyces cerevisiae]
           Length = 591
           
 Score =  113 bits (281), Expect = 3e-24
 Identities = 127/472 (26%), Positives = 208/472 (43%), Gaps = 67/472 (14%)

Query: 12  EELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGI-VQVTAPKKKV--PQEIFKLIPKLNS 68
           E L  +KV +AG +   ++ G     ++   +G+ VQ+ +  +    P    K    L  
Sbjct: 117 ETLPEEKVSIAGRIHAKRESGSKLKFYVLHGDGVEVQLMSQLQDYCDPDSYEKDHDLLKR 176

Query: 69  EDVIVVEGIVNFTPKAKLG---FEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRF 125
            D++ VEG V  T   K G     +   ++++++     LP D  G    E  TR   R+
Sbjct: 177 GDIVGVEGYVGRTQPKKGGEGEVSVFVSRVQLLTPCLHMLPADHFGFKDQE--TRYRKRY 234

Query: 126 MDL-RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFEND 184
           +DL  N    + F  RS + R  R F  +  FIE+ TP +   A  GG    P     ND
Sbjct: 235 LDLIMNKDARNRFITRSEIIRYIRRFLDQRKFIEVETPMMNVIA--GGATAKPFITHHND 292

Query: 185 A----FLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESE 240
                ++  +P+L+ + ++  GLD+V+EIG  FR E  + T H  E  + +    F ++ 
Sbjct: 293 LDMDMYMRIAPELFLKQLVVGGLDRVYEIGRQFRNEGIDMT-HNPEFTTCE----FYQAY 347

Query: 241 EEVMDLLERLILYVINYVRE---------NNEKELKILEFELNEPKKPFPRITYDEALEI 291
            +V DL++   L     V+E         + +      E ELN   +P+ RI   E LE 
Sbjct: 348 ADVYDLMDMTELMFSEMVKEITGSYIIKYHPDPADPAKELELNF-SRPWKRINMIEELEK 406

Query: 292 LSDLGKEIPWGEDIDT-EGEKLLGKYMLENE--------GAELY---------------F 327
           + ++  + P G+ + T E  + L K +++N+         A +                F
Sbjct: 407 VFNV--KFPSGDQLHTAETGEFLKKILVDNKLECPPPLTNARMLDKLVGELEDTCINPTF 464

Query: 328 IYRYPSEAKPFYIMKY-EDKPEVCKAFDLEYRGVEISSG----GQREHRHDILVEQIREK 382
           I+ +P    P  + KY  D+P +C+ F++     EI +          +     EQ R+K
Sbjct: 465 IFGHPQMMSP--LAKYSRDQPGLCERFEVFVATKEICNAYTELNDPFDQRARFEEQARQK 522

Query: 383 GLNPESF----EFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFP 430
               +      E +  A EYG+PP GG+G G +RL M + D   IREV+LFP
Sbjct: 523 DQGDDEAQLVDETFCNALEYGLPPTGGWGCGIDRLAMFLTDSNTIREVLLFP 574


>sp|Q9PR83|SYK_UREPA LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
           >gi|11271293|pir||G82937 lysyl-tRNA synthetase UU062
           [imported] - Ureaplasma urealyticum
           >gi|6899012|gb|AAF30467.1|AE002106_1 (AE002106)
           lysyl-tRNA synthetase [Ureaplasma urealyticum]
           Length = 493
           
 Score =  113 bits (280), Expect = 4e-24
 Identities = 114/457 (24%), Positives = 206/457 (44%), Gaps = 48/457 (10%)

Query: 5   HYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIP 64
           ++S E    ++ +K+ +AG +  ++   GI    I+D    +Q+   KK V  E+F    
Sbjct: 47  NFSKEELHNMDLEKLTLAGRLIGIRQTFGI----IQDFSAKLQIYINKKNVAPEVFSTFK 102

Query: 65  KLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNR 124
            L+  D+I +EG+   T   ++   +    + +++K+   LP    G V  E+  R   R
Sbjct: 103 SLDIGDIIELEGVAMKTNSDEITLNV--TNIRLVAKSLKVLPEKYHGLVDEEIKAR--QR 158

Query: 125 FMDL-RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKY--F 181
           ++DL  N    + F  RS + R  R +   +GF E+ TP +    +      F   +   
Sbjct: 159 YLDLIVNDETKNTFIKRSLIIREMRNWLDNKGFFEVETPVLQDILSGAAARPFITHHNTL 218

Query: 182 ENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEE 241
             + +L  + ++  +  +  G +KV+EIG IFR E  ++T H  E  S++  +A+++   
Sbjct: 219 NKEYYLRIATEIALKKCIIGGFEKVYEIGRIFRNEGMDST-HNPEFTSVELYIAYVDL-W 276

Query: 242 EVMDLLERLILYVINYVRENNEKELKILEFELNEPKKP--------------FPRITYDE 287
            +M L E LI ++   +   N    +    +LN+P K               F  +  DE
Sbjct: 277 YIMQLTEDLIRHIATKLNLLN-PTFRGFSIDLNKPFKKAHMVDLINEYVGVNFFEVKSDE 335

Query: 288 -ALEILSD-----LGKEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIM 341
            A+E+        L  +  +G  ++   E       +E +  E  F+Y +P +  P    
Sbjct: 336 QAIELAKKHHVKLLDHQKNFGHIVNAFFET-----FVEEKLVEPTFVYGHPLQVSPL-TK 389

Query: 342 KYEDKPEVCKAFDLEYRGVEISSGGQREH----RHDILVEQIREKGL-NPESFEF---YL 393
           K +  P     F+L     E ++     +    +++  + Q+ E  L N E+ E    ++
Sbjct: 390 KNQSDPRFVDRFELFICQKEFANAYSEINDPIDQYERFIAQLEEAKLGNDEASELDMEFI 449

Query: 394 RAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFP 430
            A EYGMPP GG G+G +RL+M +    +IR V+LFP
Sbjct: 450 EALEYGMPPTGGLGIGVDRLVMLLTSNDSIRNVLLFP 486


>sp|P46191|SYK_MYCHO LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
           >gi|581319|emb|CAA52877.1| (X74912) putative lysyl-tRNA
           synthetase [Mycoplasma hominis]
           Length = 488
           
 Score =  112 bits (278), Expect = 7e-24
 Identities = 112/429 (26%), Positives = 198/429 (46%), Gaps = 50/429 (11%)

Query: 36  FIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKL 95
           FI ++D  G +Q+ A KK + +   K    ++  D++ V G ++ T    L  +   + +
Sbjct: 72  FIVLQDNCGQMQIYANKKTLNESSAKTFSLMDFGDILSVRGTLSKTNTDALVMKA--QDM 129

Query: 96  EVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLR-NPRVMSIFKIRSSVFRATREFFYKE 154
             ++K+  PLP    G V  E   R   R++DL  N +  + F +R+ + +  RE+F   
Sbjct: 130 VTLTKSLKPLPDKFHGLVDPE--ERRRQRYVDLMMNEKTRNTFVMRTQIIKGIREYFDSL 187

Query: 155 GFIEIHTPKIIATATEGGTELFPLKYFEN----DAFLAQSPQLYKQMMMSTGLDKVFEIG 210
            +IE+ TP  I     GG    P   F N    + +L  + +L  + ++  GLD+V+EIG
Sbjct: 188 NYIEVDTP--ILNPMLGGAAAKPFITFYNATNRNFYLRIATELPLKKLIVGGLDRVYEIG 245

Query: 211 PIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILE 270
            +FR E  +TT H  E  SI+    F E+  ++  ++ER      + + + N KE+K   
Sbjct: 246 RMFRNEGVDTT-HNPEFTSIE----FYEAYSDLWGMMERTEGVFKHLMNKFNIKEVKFNG 300

Query: 271 FELNEPKKPFPRITYDEAL-------------EILSDLGKE--------IPWGEDIDTEG 309
           F++     PF R+   +A+             E + +L K+          +G  I+   
Sbjct: 301 FDMTF-NFPFKRVNMIDAMSEKINVDIRKLNEEQMFELAKKHGIKIEKFFRYGHIINELF 359

Query: 310 EKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDL----EYRGVEISSG 365
           EK + + ++E       F+Y +P E  P   +  +DK    +A       E+  +     
Sbjct: 360 EKYVEETLMEPT-----FVYGHPIEISPTAAIDPDDKRFTTRAETFIGTKEFANMFTELN 414

Query: 366 GQREHRHDILVEQIREKGLNPESFEF---YLRAFEYGMPPHGGFGLGAERLIMRMLDIGN 422
              +       + + ++  N E+ E    ++ A EYGMPP GG G+G +R IM +    +
Sbjct: 415 DPIDQLQRFENQLLEKENGNEEANEIDWDFVNALEYGMPPTGGSGMGIDRTIMTLTQNDS 474

Query: 423 IREVILFPR 431
           IR+V+LFP+
Sbjct: 475 IRDVVLFPQ 483


>dbj|BAA35676.1| (D90730) Asparaginyl-tRNA synthetase (EC  6.1.1.22)
           (asparagine-tRNA ligase) (asnRS). [Escherichia coli]
           Length = 221
           
 Score =  112 bits (278), Expect = 7e-24
 Identities = 73/223 (32%), Positives = 112/223 (49%), Gaps = 20/223 (8%)

Query: 226 EAWSIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEP--------- 276
           E W ++ E+AF    + +  L E ++ YV   V E    ++K     +++          
Sbjct: 1   EFWMLEPEVAFANLND-IAGLAEAMLKYVFKAVLEERADDMKFFAERVDKDAVSRLERFI 59

Query: 277 KKPFPRITYDEALEILSDLGKE----IPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYP 332
           +  F ++ Y +A+ IL + G++    + WG D+ +E E+    Y+ E        +  YP
Sbjct: 60  EADFAQVDYTDAVTILENCGRKFENPVYWGVDLSSEHER----YLAEEHFKAPVVVKNYP 115

Query: 333 SEAKPFYIMKYEDKPEVCKAFDLEYRGV-EISSGGQREHRHDILVEQIREKGLNPESFEF 391
            + K FY+   ED   V  A D+   G+ EI  G QRE R D+L E++ E GLN E + +
Sbjct: 116 KDIKAFYMRLNEDGKTVA-AMDVLAPGIGEIIGGSQREERLDVLDERMLEMGLNKEDYWW 174

Query: 392 YLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRR 434
           Y     YG  PH GFGLG ERLI  +  + N+R+VI FPR  R
Sbjct: 175 YRDLRRYGTVPHSGFGLGFERLIAYVTGVQNVRDVIPFPRTPR 217


>emb|CAA10905.1| (AJ222645) asparaginyl-tRNA synthetase [Arabidopsis thaliana]
           Length = 276
           
 Score =  111 bits (276), Expect = 1e-23
 Identities = 76/271 (28%), Positives = 127/271 (46%), Gaps = 22/271 (8%)

Query: 176 FPLKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMA 235
           F   +F  D +L  S + + +   S  L KV+  GP F A++ +  RHL E W+++ EMA
Sbjct: 6   FSKDFFGRDTYLTASGRFHLESYASA-LGKVYTFGPRFIADKIDNARHLAEKWNVETEMA 64

Query: 236 FIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEP---------KKPFPRITYD 286
           F E ++  MD  +    ++  YV EN ++++K +   +++               R +Y 
Sbjct: 65  FAELDD-AMDCADEYFKFLCKYVLENRDEDMKFISKRVDKTITTRLEATASSSLLRFSYT 123

Query: 287 EALEIL-----SDLGKEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIM 341
           E + +L     +    +  WG  + TE    L   + +        ++ YP   K FY+ 
Sbjct: 124 EVISLLQKATTTKFETKPEWGVALTTEHLSYLTDEIYKGP----VIVHTYPKAIKQFYVR 179

Query: 342 KYEDKPEVCKAFDLEYRGVEIS-SGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGM 400
             +DK  V  AFDL    V +  +G Q E R +IL  +I E G   E FE+YL    +G 
Sbjct: 180 LNDDKKTVA-AFDLVVPKVGVVITGSQNEERFEILDARIGESGFTREKFEWYLDLRRHGT 238

Query: 401 PPHGGFGLGAERLIMRMLDIGNIREVILFPR 431
             H G  L  E++++    + +I++ I FPR
Sbjct: 239 VKHSGISLSMEQMLLYATGLPDIKDAIPFPR 269


>gb|AAD46682.1|AF170910_1 (AF170910) SYNC2 protein [Arabidopsis thaliana]
           Length = 638
           
 Score =  111 bits (276), Expect = 1e-23
 Identities = 76/271 (28%), Positives = 127/271 (46%), Gaps = 22/271 (8%)

Query: 176 FPLKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMA 235
           F   +F  D +L  S + + +   S  L KV+  GP F A++ +  RHL E W+++ EMA
Sbjct: 368 FSKDFFGRDTYLTASGRFHLESYASA-LGKVYTFGPRFIADKIDNARHLAEKWNVETEMA 426

Query: 236 FIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEP---------KKPFPRITYD 286
           F E ++  MD  +    ++  YV EN ++++K +   +++               R +Y 
Sbjct: 427 FAELDD-AMDCADEYFKFLCKYVLENRDEDMKFISKRVDKTITTRLEATASSSLLRFSYT 485

Query: 287 EALEIL-----SDLGKEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIM 341
           E + +L     +    +  WG  + TE    L   + +        ++ YP   K FY+ 
Sbjct: 486 EVISLLQKATTTKFETKPEWGVALTTEHLSYLTDEIYKGP----VIVHTYPKAIKQFYVR 541

Query: 342 KYEDKPEVCKAFDLEYRGVEIS-SGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGM 400
             +DK  V  AFDL    V +  +G Q E R +IL  +I E G   E FE+YL    +G 
Sbjct: 542 LNDDKKTVA-AFDLVVPKVGVVITGSQNEERFEILDARIGESGFTREKFEWYLDLRRHGT 600

Query: 401 PPHGGFGLGAERLIMRMLDIGNIREVILFPR 431
             H G  L  E++++    + +I++ I FPR
Sbjct: 601 VKHSGISLSMEQMLLYATGLPDIKDAIPFPR 631


>gb|AAF02166.1|AC009853_26 (AC009853) putative asparaginyl-tRNA synthetase [Arabidopsis
           thaliana]
           Length = 638
           
 Score =  111 bits (276), Expect = 1e-23
 Identities = 76/271 (28%), Positives = 127/271 (46%), Gaps = 22/271 (8%)

Query: 176 FPLKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMA 235
           F   +F  D +L  S + + +   S  L KV+  GP F A++ +  RHL E W+++ EMA
Sbjct: 368 FSKDFFGRDTYLTASGRFHLESYASA-LGKVYTFGPRFIADKIDNARHLAEKWNVETEMA 426

Query: 236 FIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEP---------KKPFPRITYD 286
           F E ++  MD  +    ++  YV EN ++++K +   +++               R +Y 
Sbjct: 427 FAELDD-AMDCADEYFKFLCKYVLENRDEDMKFISKRVDKTITTRLEATASSSLLRFSYT 485

Query: 287 EALEIL-----SDLGKEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIM 341
           E + +L     +    +  WG  + TE    L   + +        ++ YP   K FY+ 
Sbjct: 486 EVISLLQKATTTKFETKPEWGVALTTEHLSYLTDEIYKGP----VIVHTYPKAIKQFYVR 541

Query: 342 KYEDKPEVCKAFDLEYRGVEIS-SGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGM 400
             +DK  V  AFDL    V +  +G Q E R +IL  +I E G   E FE+YL    +G 
Sbjct: 542 LNDDKKTVA-AFDLVVPKVGVVITGSQNEERFEILDARIGESGFTREKFEWYLDLRRHGT 600

Query: 401 PPHGGFGLGAERLIMRMLDIGNIREVILFPR 431
             H G  L  E++++    + +I++ I FPR
Sbjct: 601 VKHSGISLSMEQMLLYATGLPDIKDAIPFPR 631


>pir||T04993 probable aspartate--tRNA ligase (EC 6.1.1.12) T16L1.250 -
           Arabidopsis thaliana >gi|3549678|emb|CAA20589.1|
           (AL031394) putative aspartate--tRNA ligase [Arabidopsis
           thaliana] >gi|7270325|emb|CAB80093.1| (AL161584)
           putative aspartate--tRNA ligase [Arabidopsis thaliana]
           Length = 636
           
 Score =  110 bits (273), Expect = 3e-23
 Identities = 95/300 (31%), Positives = 146/300 (48%), Gaps = 50/300 (16%)

Query: 3   RTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKL 62
           RT    E++    GK+V + GWV   +  GG+ F+ +RD  GIVQV     + P E   L
Sbjct: 75  RTELCGELSVNDVGKRVHLCGWVALHRVHGGLTFLNLRDHTGIVQVRTLPDEFP-EAHGL 133

Query: 63  IPKLNSEDVIVVEGIVNFTP------KAKLGF-EIIPEKLEVISKAKTPLPLDPT----G 111
           I  +  E V++VEG V   P      K K GF E++ E +E+++  +T LP   T     
Sbjct: 134 INDMRLEYVVLVEGTVRSRPNESVNKKMKTGFVEVVAEHVEILNPVRTKLPFLVTTADEN 193

Query: 112 KVKAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFY-KEGFIEIHTPKIIATATE 170
           K   + + RL  R +DLR  ++ +   +R +V +  R +   + GFIE  T         
Sbjct: 194 KDLIKEEIRLRFRCLDLRRQQMKNNIVLRHNVVKLIRRYLEDRHGFIESGT--------- 244

Query: 171 GGTELFPLKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSI 230
                    ++     L QSPQL+KQM+M +G DK ++I   FR E+    R   E   +
Sbjct: 245 ---------FYA----LPQSPQLFKQMLMVSGFDKYYQIARCFRDEDLRADRQ-PEFTQL 290

Query: 231 DAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALE 290
           D EMAF+   E+++ L E LI  V +        E+K ++        PFPR+TY +A++
Sbjct: 291 DMEMAFMPM-EDMLKLNEDLIRKVFS--------EIKGIQL-----PDPFPRLTYADAMD 336


>emb|CAB89697.1| (AJ276418) putative lysyl tRNA synthetase [Xanthomonas campestris
           pv. campestris]
           Length = 505
           
 Score =  110 bits (272), Expect = 4e-23
 Identities = 124/476 (26%), Positives = 208/476 (43%), Gaps = 63/476 (13%)

Query: 2   LRTHYSSEITEELN-------------GKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQV 48
           +RTH++ ++  E                + VK+AG +   + +G   F  I+D  G VQ+
Sbjct: 40  VRTHFAGDLQAEFAEAETWTAEALEAADRSVKLAGRLMAKRVMGKASFAQIQDESGRVQL 99

Query: 49  TAPKKKVPQEIFKLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLD 108
              +  V  + +      +  D++ VEG +  T   +L  +     L +++K+  PLP  
Sbjct: 100 FL-QGNVLGDAYTAFKGWDVGDIVAVEGGLTRTKTGELSVKATA--LRLLTKSLRPLPDK 156

Query: 109 PTGKVKAELDTRLDNRFMDLR-NPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIAT 167
             G   ++++ R   R++DL   P    +F  RS + RA R +     F+E+ TP +   
Sbjct: 157 WHGL--SDVEQRYRQRYVDLIVTPEAREVFIKRSKIIRAIRAWLDARRFLEVETPMM--H 212

Query: 168 ATEGGTELFPLKYFEN----DAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRH 223
              GG    P     N    D +L  +P+LY + ++  GL++V+EI   FR  E  +TRH
Sbjct: 213 YIPGGATAKPFTTHHNALDLDLYLRVAPELYLKRLVVGGLERVYEINRNFR-NEGVSTRH 271

Query: 224 LNEAWSIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRI 283
             E   ++   A+  +  E+MDL E++I      V    +      + +L      F R 
Sbjct: 272 NPEFTMLELYEAY-ATYHEIMDLTEQVIRDTAQGVLGTTQVSWDGADIDL---APAFRRW 327

Query: 284 TYDEALEILSDLGKEIPWGEDIDTEG-----EKL---------LGKYML-------ENEG 322
             DEA+        EI   +  D        E+L          GK +L       E+  
Sbjct: 328 RMDEAVR---HHNPEISAADCTDRAALLRHCERLKIKVKPSYGWGKLLLEIFESTVEHTL 384

Query: 323 AELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSG----GQREHRHDILVEQ 378
            +  FI  +P E  P      + +P     F+L   G E+++G       E +      Q
Sbjct: 385 VQPTFITDHPVEVSPL-ARASDTEPGYTDRFELFINGKELANGFSELNDPEDQAARFQAQ 443

Query: 379 IREK-GLNPESFEF---YLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFP 430
           ++ K G + E+  +   Y+RA EYGM P GG G+G +RL+M +    +IR+V+LFP
Sbjct: 444 VQAKDGGDDEAMHYDADYIRALEYGMAPTGGLGIGIDRLVMLLTGSTSIRDVLLFP 499


>sp|Q9KU60|SYK_VIBCH LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
           >gi|11271287|pir||A82296 lysyl-tRNA synthetase, heat
           inducible VC0664 [imported] - Vibrio cholerae (group O1
           strain N16961) >gi|9655101|gb|AAF93829.1| (AE004152)
           lysyl-tRNA synthetase, heat inducible [Vibrio cholerae]
           Length = 512
           
 Score =  109 bits (271), Expect = 5e-23
 Identities = 125/463 (26%), Positives = 202/463 (42%), Gaps = 53/463 (11%)

Query: 7   SSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKL 66
           S E  E LN   V +AG V   +      F+ I++  G +Q  A  K+V QE+      L
Sbjct: 64  SKEELEALN-HVVSIAGRVMAKRG----PFLVIQETSGRIQAYA-SKEVQQELKDKYQGL 117

Query: 67  NSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFM 126
           +  D+I V+G ++ + K  L   +  E+ ++++KA  PLP    G    E+  R   R++
Sbjct: 118 DIGDIIGVQGALHKSGKGDLYVNM--EQFQLLTKALRPLPEKFHGLTDQEM--RYRQRYV 173

Query: 127 DLR-NPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFEN-- 183
           DL  N    + F +RS V  A R F   + F+E+ TP +      GG    P     N  
Sbjct: 174 DLIVNENSRNAFIVRSKVMSAIRNFMISKQFMEVETPMM--HVIPGGASARPFITHHNAL 231

Query: 184 --DAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEE 241
               +L  +P+LY + ++  G D+VFEI   FR  E  + RH  E   ++  MA+ +  +
Sbjct: 232 DMPMYLRIAPELYLKRLVVGGFDRVFEINRNFR-NEGLSPRHNPEFTMMEFYMAYAD-YK 289

Query: 242 EVMDLLERLILYVI------------NYVRENNEKELKILEFELNEPKKP----FPRITY 285
           ++MDL E L+  V              +  E   K  ++  F+  +   P       +T 
Sbjct: 290 DLMDLTEELLSSVALEVLGSTSMPYGEHTVEFGGKYARMSMFDAIKHYNPNHAQIQALTE 349

Query: 286 DEALEILSDLGKEIPWGEDIDTEGEKLLGKYMLENEG-------AELYFIYRYPSEAKPF 338
           ++      DL   I     +D E     G+ + E  G        +  FI  YP++  P 
Sbjct: 350 EDIQN--RDLMVSIAKSVHVDVEPFWTCGQLLEEIFGETAEPKLMQPTFITGYPADISPL 407

Query: 339 YIMKYEDKPEVCKAFDLEYRGVEISSG----GQREHRHDILVEQIREKGLNPESFEF--- 391
              + +D P     F+    G E+++G       E +      Q+  K    +   F   
Sbjct: 408 -ARRSDDNPFFTDRFEFFIGGREVANGFSELNDAEDQDARFKAQVEAKESGDDEAMFYDA 466

Query: 392 -YLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDR 433
            Y+ A E+G+PP  G G+G +RL+M + +   IR+VILFP  R
Sbjct: 467 DYITALEHGLPPTAGQGIGIDRLVMLLTNTHTIRDVILFPAMR 509


>gb|AAF53577.2| (AE003652) CG17938 gene product [Drosophila melanogaster]
           Length = 1160
           
 Score =  107 bits (264), Expect = 3e-22
 Identities = 92/298 (30%), Positives = 145/298 (47%), Gaps = 31/298 (10%)

Query: 3   RTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKL 62
           RTH   E+T     +KV + GW+ E + +   KF  +RD  G  QV    K    E +  
Sbjct: 483 RTHNCGELTSNDINEKVVICGWL-EFQRMN--KFFILRDAYGQTQVLLSPKTYGLEEYAE 539

Query: 63  IPKLNSEDVIVVEGIV------NFTPKAKLGF-EIIPEKLEVISKAKTPLPLDPTGKVKA 115
              +  E ++ VEG V         PK + G  E+  +K+ V++ AK  LP +     +A
Sbjct: 540 TG-VPIESIVRVEGTVIPRPAATINPKMQTGHVEVEADKVVVLNPAKKNLPFEIRKFNRA 598

Query: 116 ELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKE-GFIEIHTPKIIATATEGGTE 174
               RL +R++DLR   +    ++RS+V    RE+     GF+E+ TP +    T GG +
Sbjct: 599 GERLRLTHRYLDLRFNDMQHNLRLRSAVIMKMREYLINYLGFVEVETPTLFRR-TPGGAQ 657

Query: 175 LF--PLKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDA 232
            F  P +   +   L QSPQ +KQM+MS G+D+ F++   +R E     R   E   +D 
Sbjct: 658 EFVVPTRKAGHFYSLVQSPQQFKQMLMSGGIDRYFQVARCYRDEATRPDRQ-PEFTQLDI 716

Query: 233 EMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALE 290
           E++F  S +++M L+E  + Y       +  K+   L+        PF RITY+EA+E
Sbjct: 717 ELSF-TSRDDIMQLIEETLRY-------SWPKDFPRLQ-------TPFRRITYEEAME 759


>sp|P47382|SYK_MYCGE LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
           >gi|1361711|pir||A64215 lysine--tRNA ligase (EC 6.1.1.6)
           - Mycoplasma genitalium >gi|3844726|gb|AAC71353.1|
           (U39693) lysyl-tRNA synthetase (lysS) [Mycoplasma
           genitalium]
           Length = 490
           
 Score =  106 bits (261), Expect = 7e-22
 Identities = 120/458 (26%), Positives = 205/458 (44%), Gaps = 57/458 (12%)

Query: 12  EELNGKK-VKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSED 70
           EEL  K  V +AG +  ++      F+ I+D +G VQ+   KK  P+        ++  D
Sbjct: 51  EELKKKATVSLAGRIIAIRQT----FLIIQDFDGQVQLYINKKIHPKLFDYFNEFVDIGD 106

Query: 71  VIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLR- 129
            IVV G    T    L   +  E++++I+K     P    G    +++TR   RF+DL  
Sbjct: 107 QIVVSGKPMLTKTKVLTLAV--EEMKIIAKCLLVPPEKWHGLT--DIETRARKRFLDLTY 162

Query: 130 NPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFEN----DA 185
           N  +  +F  R+ + ++ R F  + GFIE+ TP + A    GG    P K   N    D 
Sbjct: 163 NLAMRDVFLKRTKIIKSIRSFLDQNGFIEVETPTLQAVL--GGANAKPFKTHYNALKADF 220

Query: 186 FLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMD 245
           +L  + ++  + ++  G +KV+E+G +FR E  +TT H  E  SI+   A+ + E  ++ 
Sbjct: 221 YLRIANEIALKKLIIGGFNKVYEMGKMFRNEGVDTT-HNPEFTSIEIYQAYADFEVMLV- 278

Query: 246 LLERLILYVINYVREN----NEKELKILEFELNEPKKPFPRITYDEALEILSDLG-KEIP 300
           L+E+LI  +   + +     N K + +        K PF +IT  E ++ ++ +    + 
Sbjct: 279 LVEKLIQSLCESLNQFSFNWNNKTINL--------KTPFHKITMVELIKKVTGIDFNSVK 330

Query: 301 WGEDIDTEGEK-----------------LLGKYMLENEGAELYFIYRYPSEAKPFYIMKY 343
             +      EK                 L  +   E    E  F+  YP    P    + 
Sbjct: 331 DDQSAILLAEKHHVKLAKHQQNKQHIINLFFEQFCEQTLIEPTFVTHYPKAVSPL-AKQD 389

Query: 344 EDKPEVCKAFDLEYRGVEISSGGQREH----RHDILVEQIREKGL-NPESFEF---YLRA 395
              PE  + F+L   G EI++     +    +     +Q+ EK L N E+ E    +L A
Sbjct: 390 PSNPEFTQRFELFINGKEIANAYSELNDPLEQRKRFEQQLEEKQLGNDETSELDESFLEA 449

Query: 396 FEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDR 433
             +GM    G G+G +RL+M + +  +IR+V+ FP+ R
Sbjct: 450 LSFGMVNTAGLGIGIDRLVMLLCECNSIRDVVFFPQLR 487


>pir||S70779 asparagine--tRNA ligase (EC 6.1.1.22) - Xenorhabdus nematophilus
           (fragment)
           Length = 192
           
 Score = 99.1 bits (243), Expect = 9e-20
 Identities = 59/160 (36%), Positives = 86/160 (52%), Gaps = 10/160 (6%)

Query: 280 FPRITYDEALEILSDLGKEIP----WGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEA 335
           F ++ Y +A++IL + G++      WG D+ +E E+    Y+ E        +  YP   
Sbjct: 27  FIQLDYTDAIKILENCGQKFENPYFWGVDLSSEHER----YLAEKHFEAPVIMKNYPKNI 82

Query: 336 KPFYIMKYEDKPEVCKAFDLEYRGV-EISSGGQREHRHDILVEQIREKGLNPESFEFYLR 394
           K FY+   ED   V  A D+   G+ EI  G QRE R D+L +++ E GLN E + +Y  
Sbjct: 83  KAFYMRMNEDGKTVA-AMDVLAPGIGEIIGGSQREERLDMLDKRLEEMGLNKEDYWWYRD 141

Query: 395 AFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRR 434
              YG  PH GFGLG ERL+  +  + N+R+VI FPR  R
Sbjct: 142 LRRYGTVPHAGFGLGFERLVAYVTGVANVRDVIPFPRTPR 181


>dbj|BAA99139.1| (AP002548) lysyl tRNA synthetase [Chlamydophila pneumoniae J138]
           Length = 527
           
 Score = 97.9 bits (240), Expect = 2e-19
 Identities = 117/477 (24%), Positives = 216/477 (44%), Gaps = 60/477 (12%)

Query: 7   SSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVP----QEIFKL 62
           +SE     +  +V+ AG +   + +G   F  I D    +QV   ++        E  ++
Sbjct: 55  NSEAAMSRSTPRVRFAGRLVLFRAMGKNAFGQILDHNQTIQVMFNREFTSVHGLSEDAEI 114

Query: 63  IP------KLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAE 116
            P      KL+  D++ ++G + FT   +L   ++ E + ++ K+   LP    G   ++
Sbjct: 115 TPIKFIEKKLDLGDILGIDGYLFFTHSGEL--TVLVETVTLLCKSLLSLPDKHAGL--SD 170

Query: 117 LDTRLDNRFMDLRNPRVMS-IFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTEL 175
            + R   R++DL + R +S  F  RS + +  R +    GF+E+ TP  I     GG E 
Sbjct: 171 KEVRYRKRWLDLISSREVSDTFVKRSYIIKLIRNYMDAHGFLEVETP--ILQNIYGGAEA 228

Query: 176 FP----LKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSID 231
            P    ++   ++ FL  S ++  + ++  G  +++E+G +FR E  + T H  E   I+
Sbjct: 229 KPFTTTMEALHSETFLRISLEIALKKILVGGAPRIYELGKVFRNEGIDRT-HNPEFTMIE 287

Query: 232 AEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEP-----KKPFPRITYD 286
           A  A+++  +EVM  +E L+ +++  V  N++    +  +  + P     K P+ R+T  
Sbjct: 288 AYAAYMD-YKEVMVFVENLVEHLVRAV--NHDNTSLVYSYWKHGPQEVDFKAPWIRMTMK 344

Query: 287 EAL--------EILSD------LGKEIPWGEDIDTEGEK------LLGKYMLENEGAELY 326
           E++        ++ SD      L K+  + E       +      L  + + +N  A  +
Sbjct: 345 ESIATYAGIDVDVHSDQKLKEILKKKTTFPETAFATASRGMLIAALFDELVSDNLIAP-H 403

Query: 327 FIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEI----SSGGQREHRHDILVEQIREK 382
            I  +P E  P             + F+    G E+    S       + ++L +Q  +K
Sbjct: 404 HITDHPVETTPLCKTLRSGDTAFVERFESFCLGKELCNAYSELNDPIRQRELLEQQHTKK 463

Query: 383 GLNPES-----FEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRR 434
            L P+S      E +L A   GMPP GGFG+G +RL+M + +  +IR+V+ FP  RR
Sbjct: 464 ELLPDSECHPIDEEFLEALCQGMPPAGGFGIGVDRLVMILTNAASIRDVLYFPVMRR 520


>sp|Q9Z6X5|SYK_CHLPN LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
           >gi|7437608|pir||E72016 lysine--tRNA ligase (EC 6.1.1.6)
           [similarity] - Chlamydophila pneumoniae (strains CWL029
           and AR39) >gi|4377254|gb|AAD19069.1| (AE001673) Lysyl
           tRNA Synthetase [Chlamydophila pneumoniae CWL029]
           >gi|7189844|gb|AAF38715.1| (AE002251) lysyl-tRNA
           synthetase [Chlamydophila pneumoniae AR39]
           Length = 527
           
 Score = 97.5 bits (239), Expect = 3e-19
 Identities = 117/477 (24%), Positives = 216/477 (44%), Gaps = 60/477 (12%)

Query: 7   SSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVP----QEIFKL 62
           +SE     +  +V+ AG +   + +G   F  I D    +QV   ++        E  ++
Sbjct: 55  NSEAAMSRSTPRVRFAGRLVLFRAMGKNAFGQILDHNQTIQVMFNREFTSVHGLSEDAEI 114

Query: 63  IP------KLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAE 116
            P      KL+  D++ ++G + FT   +L   ++ E + ++ K+   LP    G   ++
Sbjct: 115 TPIKFIEKKLDLGDILGIDGYLFFTHSGEL--TVLVETVTLLCKSLLSLPDKHAGL--SD 170

Query: 117 LDTRLDNRFMDLRNPRVMS-IFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTEL 175
            + R   R++DL + R +S  F  RS + +  R +    GF+E+ TP  I     GG E 
Sbjct: 171 KEVRYRKRWLDLISSREVSDTFVKRSYIIKLIRNYMDAHGFLEVETP--ILQNIYGGAEA 228

Query: 176 FP----LKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSID 231
            P    ++   ++ FL  S ++  + ++  G  +++E+G +FR E  + T H  E   I+
Sbjct: 229 KPFTTTMEALHSEMFLRISLEIALKKILVGGAPRIYELGKVFRNEGIDRT-HNPEFTMIE 287

Query: 232 AEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEP-----KKPFPRITYD 286
           A  A+++  +EVM  +E L+ +++  V  N++    +  +  + P     K P+ R+T  
Sbjct: 288 AYAAYMD-YKEVMVFVENLVEHLVRAV--NHDNTSLVYSYWKHGPQEVDFKAPWIRMTMK 344

Query: 287 EAL--------EILSD------LGKEIPWGEDIDTEGEK------LLGKYMLENEGAELY 326
           E++        ++ SD      L K+  + E       +      L  + + +N  A  +
Sbjct: 345 ESIATYAGIDVDVHSDQKLKEILKKKTTFPETAFATASRGMLIAALFDELVSDNLIAP-H 403

Query: 327 FIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEI----SSGGQREHRHDILVEQIREK 382
            I  +P E  P             + F+    G E+    S       + ++L +Q  +K
Sbjct: 404 HITDHPVETTPLCKTLRSGDTAFVERFESFCLGKELCNAYSELNDPIRQRELLEQQHTKK 463

Query: 383 GLNPES-----FEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRR 434
            L P+S      E +L A   GMPP GGFG+G +RL+M + +  +IR+V+ FP  RR
Sbjct: 464 ELLPDSECHPIDEEFLEALCQGMPPAGGFGIGVDRLVMILTNAASIRDVLYFPVMRR 520


>pir||T41563 hypothetical protein SPCC736.06 - fission yeast
           (Schizosaccharomyces pombe) >gi|3845470|emb|CAA19270.1|
           (AL023705) aspartyl-trna synthetase [Schizosaccharomyces
           pombe]
           Length = 611
           
 Score = 96.0 bits (235), Expect = 8e-19
 Identities = 83/308 (26%), Positives = 141/308 (44%), Gaps = 51/308 (16%)

Query: 14  LNGKKVKVAGWV-------------QEVKDLGGI--------KFIWIRDREGIVQVTAPK 52
           L G KV + GW+              +++D  G         K I  + RE +V  T   
Sbjct: 13  LVGTKVSIQGWLVATSRQVSKSISFHQLRDTHGTILQLLSTDKIILQQKREPLVSSTDFS 72

Query: 53  KKVPQEIFKLIPKLNSEDVIVVEGIVNFTPKAKLG----FEIIPEKLEVISKAKTPLPLD 108
           ++    + + +  +  E V+ V G +   P+        FE+  E +++++ AK  L L 
Sbjct: 73  QQKSTSVMRTLSSIPPESVVQVTGKLQRRPEHDRRPGNEFELHVEDVKLLNVAKN-LQLF 131

Query: 109 PTGKVKAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATA 168
           P G  K  +  +L NR + LR P+  S  + RS +      FF    F E+ TP +  + 
Sbjct: 132 P-GDEKPGMRIQLANRHIQLRAPKYNSYLRQRSRLAYQVHSFFNDREFCEVETPLLFKST 190

Query: 169 TEGGTE------LFPLKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTR 222
            EG  E      L P K++     L QSPQ YKQ++M++G+   ++I   FR E+    R
Sbjct: 191 PEGAREFVVPSRLNPGKFYA----LPQSPQQYKQILMASGIGNYYQIARCFRDEDLRFDR 246

Query: 223 HLNEAWSIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPR 282
              E   ID EM+F++   E+M+++E L++ ++++      K + +         KPF  
Sbjct: 247 Q-PEFTQIDLEMSFVDKPHEIMEVVEDLLVRLVSFA-----KGITL--------AKPFQH 292

Query: 283 ITYDEALE 290
           ITY  A++
Sbjct: 293 ITYQHAID 300


>pir||E70155 aspartate--tRNA ligase (EC 6.1.1.12) aspS - Lyme disease spirochete
           >gi|2688349|gb|AAB91506.1| (AE001149) aspartyl-tRNA
           synthetase (aspS) [Borrelia burgdorferi]
           Length = 506
           
 Score = 91.3 bits (223), Expect = 2e-17
 Identities = 61/204 (29%), Positives = 99/204 (47%), Gaps = 18/204 (8%)

Query: 88  FEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRAT 147
           FEI+ + +E+ISK    LP        A  +++L+ R++DLR   + +   +R       
Sbjct: 11  FEILAKNIEIISKCNE-LPFMIEDDNNASENSKLEYRYLDLRRDSLKNKIILRCQATHLI 69

Query: 148 REFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFLA--QSPQLYKQMMMSTGLDK 205
           R F  K  F+E+ TP  + +  EG  +          +F A  QSPQLYKQ++M  G DK
Sbjct: 70  RNFLIKRKFLELETPTFVKSTPEGARDFVIPSRIHKGSFYALPQSPQLYKQLIMIAGFDK 129

Query: 206 VFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKE 265
            F+I   +R E+    R   E   +D EM+F++ +E +  L+E ++  +           
Sbjct: 130 YFQIARCYRDEDSRGDRQ-PEFTQLDLEMSFVK-KENIFKLIENMLFLIFKNC------- 180

Query: 266 LKILEFELNEPKKPFPRITYDEAL 289
                  +N PKK F +ITY +A+
Sbjct: 181 -----ININLPKK-FKKITYKKAM 198


 Score = 69.1 bits (166), Expect = 1e-10
 Identities = 39/103 (37%), Positives = 56/103 (53%), Gaps = 6/103 (5%)

Query: 336 KPFYIMKYEDKPE--VCKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPES----F 389
           K  YI   E  P+  + + +DL   GVE+ SG  R H  ++     +  G   E     F
Sbjct: 373 KKQYIANLEKNPKKTIGEIYDLVLNGVELGSGSIRIHNKELQQRIFKIIGFQKEKSEDRF 432

Query: 390 EFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRD 432
            F+L+A EYG P HGG  +G +RLIM M    +I++VILFP++
Sbjct: 433 GFFLKALEYGAPNHGGIAIGIDRLIMLMTKSTSIKDVILFPKN 475


>pir||S77842 probable asparagine--tRNA ligase (EC 6.1.1.22) - Mycoplasma
           capricolum (fragment) >gi|530408|emb|CAA83705.1|
           (Z33026) Asn-tRNA synthetase [Mycoplasma capricolum]
           Length = 172
           
 Score = 89.3 bits (218), Expect = 8e-17
 Identities = 60/167 (35%), Positives = 85/167 (49%), Gaps = 14/167 (8%)

Query: 280 FPRITYDEALEILSDLG--------KEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRY 331
           F   TY EA+EIL             +I +G D+ TE E+    Y+ E       F+  Y
Sbjct: 10  FKVTTYTEAIEILKQAVANGHKFEVSDIEFGLDLGTEHER----YICEQVNKAPTFVTNY 65

Query: 332 PSEAKPFYIMKYEDKPEVCKAFDLEYRGV-EISSGGQREHRHDILVEQIREKGLNPESFE 390
           P E K FY+ + ED   V  A DL   G+ E+  G QRE  ++ L+++ +E  ++ +  E
Sbjct: 66  PKEIKAFYMKQNEDNKTVA-AVDLLVPGIGELVGGSQREDNYEKLIKRCKEVNIDIDQLE 124

Query: 391 FYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRRRLV 437
           +Y     YG     GFGLG ERLIM +    NIR+VI FPR  + L+
Sbjct: 125 WYNNLRLYGYYKSAGFGLGFERLIMYITGASNIRDVIPFPRTPKNLL 171


>gi|6325153 Aspartyl-tRNA synthetase, mitochondrial; Msd1p [Saccharomyces
           cerevisiae] >gi|135101|sp|P15179|SYDM_YEAST
           ASPARTYL-TRNA SYNTHETASE, MITOCHONDRIAL (ASPARTATE--TRNA
           LIGASE) (ASPRS) >gi|2144551|pir||SYBYDM aspartate--tRNA
           ligase (EC 6.1.1.12), mitochondrial - yeast
           (Saccharomyces cerevisiae) >gi|172872|gb|AAA35137.1|
           (M26020) aspartyl-tRNA synthetase [Saccharomyces
           cerevisiae] >gi|173036|gb|AAA35173.1| (M24418)
           mitochondrial aspartyl-tRNA synthetase [Saccharomyces
           cerevisiae] >gi|1151223|gb|AAB68196.1| (U43281) Msd1p
           [Saccharomyces cerevisiae]
           Length = 658
           
 Score = 88.5 bits (216), Expect = 1e-16
 Identities = 78/256 (30%), Positives = 126/256 (48%), Gaps = 37/256 (14%)

Query: 15  NGKKVKVAGWVQEVKDLGGIKFIW--IRDREG-IVQVTAPKKKVPQEIFKLIPKLNSEDV 71
           +G+K+ + GW+++     G   I+  +RD  G I+Q+   K         L+     EDV
Sbjct: 46  SGQKIVLNGWIEQKPKRVGKNLIFGLLRDSNGDIIQLVDNKS--------LLKGFTLEDV 97

Query: 72  IVVEGIVNFTPKAKLGFEIIPE---KLEVISKAKTPLPLDPTGKVKAEL-DTRL------ 121
           +   GI++   K KL  E   E   +LE I+       L+ + K  A++ D +L      
Sbjct: 98  VQAVGILSL--KRKLSNEDADEYEVQLEDITV------LNASNKKPAQMQDFKLSAIYPP 149

Query: 122 DNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTE-LFPLKY 180
           + R++ LRNP+     K RSS+ +  R  F    F E+ TP +     EG  E L P + 
Sbjct: 150 EFRYLQLRNPKYQDFLKKRSSISKEIRNSFNNFDFTEVETPMLFKATPEGAREFLVPTRT 209

Query: 181 FENDA-----FLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMA 235
             +D       L QSPQ YKQ++M++G++K +++   FR E+    R   E   +D EMA
Sbjct: 210 KRSDGKPSFYALDQSPQQYKQLLMASGVNKYYQMARCFRDEDLRADRQ-PEFTQVDMEMA 268

Query: 236 FIESEEEVMDLLERLI 251
           F  S E+VM ++E+ +
Sbjct: 269 FANS-EDVMKIIEKTV 283


>dbj|BAA90843.1| (AB031211) LysS [Bacillus halodurans]
           Length = 310
           
 Score = 84.7 bits (206), Expect = 2e-15
 Identities = 87/319 (27%), Positives = 146/319 (45%), Gaps = 49/319 (15%)

Query: 155 GFIEIHTPKIIATATEGGTELFPLKYFEN----DAFLAQSPQLYKQMMMSTGLDKVFEIG 210
           G++E+ TP +   +  GG    P     N      ++  + +L+ + ++  G++KV+EIG
Sbjct: 3   GYLEVETPTM--HSIPGGASARPFVTHHNALDMTLYMRIAIELHLKRLIVGGMEKVYEIG 60

Query: 211 PIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILE 270
            +FR  E  +TRH  E   I+   A+ +  + +M+L E LI ++   V       +   E
Sbjct: 61  RVFR-NEGVSTRHNPEFTMIELYEAYADYND-IMELTELLIAHIAKDVLGTTT--ITYGE 116

Query: 271 FELN-EPKKPFPRITYDEALEILSDLGKEIPWGEDIDTEGEKLLGKY------------- 316
            E+N EPK  + R+   EA++   + G +  W E  D E   L  ++             
Sbjct: 117 HEVNLEPK--WRRVHMVEAIK--EETGVDF-WNEMSDEEARALAKEHNVPVKETMTYGHV 171

Query: 317 -------MLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSG---- 365
                   +E +  +  F+Y +P    P    K  D P     F+L   G E ++     
Sbjct: 172 VNEFFEHFVEEKLIQPTFVYGHPVAISPL-AKKNPDDPRFTDRFELFIVGREHANAFSEL 230

Query: 366 ----GQREHRHDILVEQIREKGLNPESF--EFYLRAFEYGMPPHGGFGLGAERLIMRMLD 419
                QR      LVE  RE+G +      E ++ + EYGMPP GG G+G +RL+M + +
Sbjct: 231 NDPIDQRHRFEQQLVE--REQGDDEAHMMDEDFVESLEYGMPPTGGLGIGIDRLVMLLTN 288

Query: 420 IGNIREVILFPRDRRRLVP 438
             +IR+V+LFP+ R +  P
Sbjct: 289 SPSIRDVLLFPQMRHKDSP 307


>sp|Q56112|SYN_SALTI ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRNA LIGASE) (ASNRS)
           >gi|1435180|emb|CAA61904.1| (X89757) asparaginyl-tRNA
           synthetase [Salmonella typhi]
           Length = 109
           
 Score = 83.1 bits (202), Expect = 6e-15
 Identities = 48/105 (45%), Positives = 60/105 (56%), Gaps = 2/105 (1%)

Query: 331 YPSEAKPFYIMKYEDKPEVCKAFDLEYRGV-EISSGGQREHRHDILVEQIREKGLNPESF 389
           YP E K FY+   ED   V  A D+   G+ EI  G QRE R D+L  ++ E GLN E +
Sbjct: 2   YPKEIKAFYMRLNEDGKTVA-AMDVLAPGIGEIIGGSQREERLDVLDARMAEMGLNKEDY 60

Query: 390 EFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRR 434
            +Y     YG  PH GFGLG ERLI  +  + N+R+VI FPR  R
Sbjct: 61  WWYSDLRRYGTVPHSGFGLGFERLIAYVTGVQNVRDVIPFPRTPR 105


>pir||C75215 asparaginyl-tRNA synthetase related protein PAB2356 - Pyrococcus
           abyssi (strain Orsay) >gi|5457679|emb|CAB49170.1|
           (AJ248283) asparaginyl-tRNA synthetase related protein
           [Pyrococcus abyssi]
           Length = 294
           
 Score = 75.3 bits (182), Expect = 1e-12
 Identities = 76/252 (30%), Positives = 113/252 (44%), Gaps = 44/252 (17%)

Query: 187 LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTT--RHLNEAWSIDAEMAFIESEEEVM 244
           L  S  L+KQ+ ++ GL+K+F + P  R E       RH  E   +D E+   + ++ VM
Sbjct: 72  LTHSMILHKQLAIAMGLEKIFVLSPNIRLESRRKDDGRHSYEFTQLDFEIEGAKMKD-VM 130

Query: 245 DLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIPWGED 304
            L+E LI  +     E   +E              FPR  + +  +   D+ +E    E 
Sbjct: 131 RLIEELIYGLFRKAEEWTGRE--------------FPRARHFKVYDY-KDILEEFGSDEK 175

Query: 305 IDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPE--VCKAFDL--EYRGV 360
              E E             E ++I   P E   FY     D+ E  V K +DL   Y   
Sbjct: 176 ASMEME-------------EPFWIVNIPRE---FY-----DREENGVWKNYDLILPYGYG 214

Query: 361 EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYG-MPPHGGFGLGAERLIMRMLD 419
           E+SSGG+RE  ++ +V +IR  GL  +SF  YL     G + P  G G+G ERL+  ++ 
Sbjct: 215 EVSSGGEREWEYEKIVAKIRAAGLKEDSFRPYLEIARAGKLKPSAGAGIGVERLVRFIVG 274

Query: 420 IGNIREVILFPR 431
             +I EV  FPR
Sbjct: 275 AKHIAEVQPFPR 286


>pir||E82050 lysyl-tRNA synthetase-related protein VC2655 [imported] - Vibrio
           cholerae (group O1 strain N16961)
           >gi|9657247|gb|AAF95796.1| (AE004331) lysyl-tRNA
           synthetase-related protein [Vibrio cholerae]
           Length = 349
           
 Score = 71.4 bits (172), Expect = 2e-11
 Identities = 88/326 (26%), Positives = 148/326 (44%), Gaps = 40/326 (12%)

Query: 134 MSIFKIRSSVFRATREFFYKEGFIEIHTPKII-ATATEGGTELFPLK-----YFENDAF- 186
           +S  K R+++ R  REFF +   +E+ TP +  AT T+     F  +     Y +  A  
Sbjct: 37  ISQLKQRATLLRQIREFFAERNVLEVETPAMSHATVTDIHLHTFKTEFVGPGYAKGSALH 96

Query: 187 LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEE----HNTTRHLNEAWSIDAEMAFIESEEE 242
           L  SP+ + + +++ G   ++++G  FR EE    HN    + E + I  +   +  E  
Sbjct: 97  LMTSPEFHMKRLLAAGSGCIYQLGKAFRNEENGRYHNPEFTMLEWYRIGFDHHALMDE-- 154

Query: 243 VMDLLERLILYVINYVREN-NEKELKILEF-ELNEPKKPFPRITYDEALEILSDLGKEIP 300
            MD L +L+L   +  R    E  L +L    L E  +   ++    A   LSD+ +   
Sbjct: 155 -MDALLQLVLRCGSAERMTYQEAFLNVLGVCPLEEEMRELKQVA---ATLGLSDIAEP-- 208

Query: 301 WGEDIDTEGEKLLGKYMLENEGAELY--FIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYR 358
             ED DT  + LL    +E +  ++   F+Y +P+       +   D P V   F++ ++
Sbjct: 209 -EEDRDTLLQ-LLFSIGIEPKIGQITPAFVYDFPASQAALAKINPAD-PRVADRFEVYFK 265

Query: 359 GVEISSGGQREHRHDILVEQIR----------EKGLNPESFEFYL-RAFEYGMPPHGGFG 407
           G+E+++G    H  D   EQ+           E GL  +  +++L  A E G+P   G  
Sbjct: 266 GIELANGF---HELDNPAEQLARFKADNAKRLEMGLTEQPIDYHLIAALEAGLPECAGVA 322

Query: 408 LGAERLIMRMLDIGNIREVILFPRDR 433
           LG +RLIM  L   +I +V  FP  R
Sbjct: 323 LGIDRLIMLALGEDHIDKVTAFPFPR 348


>sp|Q9Z614|SYK3_BUCAP PUTATIVE LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS) (GX)
           >gi|4378708|gb|AAD19636.1| (AF108665) lysyl-tRNA
           synthetase homolog [Buchnera aphidicola]
           Length = 324
           
 Score = 70.2 bits (169), Expect = 4e-11
 Identities = 76/325 (23%), Positives = 149/325 (45%), Gaps = 49/325 (15%)

Query: 140 RSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPL--KYF-------ENDAFLAQS 190
           RS +    R FF K+  +E+ TP I++ +      L P    YF       + + +L  S
Sbjct: 17  RSKIIADIRSFFLKKNIMEVETP-ILSQSGVTDVNLMPFITNYFSFNDNIKKKNLWLITS 75

Query: 191 PQLYKQMMMSTGLDKVFEIGPIFRAEE----HNTTRHLNEAWSIDAEMAFIESEEEVMDL 246
           P+ + + ++S G   +++I   FR +E    HN    + E + +   M      E++++ 
Sbjct: 76  PEYHMKRLLSAGSGSIYQICRSFRNQEFGQYHNPEFTMLEWYQLSCSM------EKMIEE 129

Query: 247 LERLILYVINYVRENN-------EKELKI--LEFELNEPKKPFPRITYDEALEILSDLGK 297
           ++     ++N+ + +         K LKI  L   L+E  + + +      + + +DL +
Sbjct: 130 IDFFFQKILNFNKADKISYQEVFMKFLKIDPLSTSLSELFQCYKKFNLKNLIYLENDLNQ 189

Query: 298 EIPWGEDIDT-EGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLE 356
            I   E+I T + +  LGK        +  F+Y +PSE      +  +D   V + F++ 
Sbjct: 190 LI---ENIFTLQIQPFLGK-------EKPLFVYHFPSEQACLASINKKDS-RVSERFEIF 238

Query: 357 YRGVEISSGGQR-----EHRHDILVEQIREKGLN-PESF--EFYLRAFEYGMPPHGGFGL 408
           ++G+E+ +G        E R   + +  +   +N PE    +++L A  +G+P   G  +
Sbjct: 239 FKGIELGNGFHELTDYFEQRKRFIKDNRKRCDMNLPEQKIDDYFLDAIHHGLPTCSGVAI 298

Query: 409 GAERLIMRMLDIGNIREVILFPRDR 433
           G +RLIM  L+  +I +V+ F  +R
Sbjct: 299 GLDRLIMIALNKNSIDQVMSFSFER 323


>gb|AAD12351.1| (U01814) unknown [Mycoplasma genitalium]
           Length = 177
           
 Score = 69.5 bits (167), Expect = 7e-11
 Identities = 38/102 (37%), Positives = 55/102 (53%), Gaps = 2/102 (1%)

Query: 333 SEAKPFYIMKYEDKPE--VCKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPESFE 390
           S+ K  +I  +E      + + FDL   G EI SG  R +   +    +    ++P  F 
Sbjct: 48  SKPKQEWIDNFESNKNEALSEQFDLVLNGFEIGSGSIRINDPIVQKRLMNSLNIDPNKFA 107

Query: 391 FYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRD 432
           F L A++YG P HGG GLG +RL+M +    NIREVI FP++
Sbjct: 108 FLLEAYQYGAPVHGGMGLGIDRLMMILNQTDNIREVIAFPKN 149


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.320    0.141    0.408 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 167256269
Number of Sequences: 2977
Number of extensions: 7505725
Number of successful extensions: 18700
Number of sequences better than 1.0e-10: 177
Number of HSP's better than  0.0 without gapping: 53
Number of HSP's successfully gapped in prelim test: 124
Number of HSP's that attempted gapping in prelim test: 18101
Number of HSP's gapped (non-prelim): 247
length of query: 438
length of database: 189,106,746
effective HSP length: 56
effective length of query: 382
effective length of database: 155,591,474
effective search space: 59435943068
effective search space used: 59435943068
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 166 (69.1 bits)