BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0646 (aspS) DE:aspartyl-tRNA synthetase (aspS)
(438 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||A75071 aspartyl-tRNA synthetase (asps) PAB0646 - Pyrococcus... 889 0.0
sp|O58776|SYD_PYRHO ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 844 0.0
sp|Q52428|SYD_PYRKO ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 773 0.0
pdb|1B8A|A Chain A, Aspartyl-Trna Synthetase >gi|4388837|pdb|1B8... 770 0.0
gi|11498525 aspartyl-tRNA synthetase (aspS) [Archaeoglobus fulgi... 527 e-149
sp|Q58950|SYD_METJA ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 514 e-145
sp|O26328|SYD_METTH ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 495 e-139
sp|O24822|SYD_HALVO ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 412 e-114
sp|Q9Y9U7|SYD_AERPE ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 404 e-112
pir||C72527 probable aspartyl-tRNA synthetase APE2192 - Aeropyru... 397 e-109
emb|CAC12075.1| (AL445066) aspartyl-tRNA synthetase related prot... 390 e-107
gb|AAK40519.1| Aspartyl-tRNA synthetase (aspS) [Sulfolobus solfa... 383 e-105
sp|O07683|SYD_HALSA ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 370 e-101
gb|AAF61689.1| (AF219996) aspartyl-tRNA synthetase 2 [Thermus th... 326 2e-88
pir||H75443 aspartyl-tRNA synthetase, non-discriminating - Deino... 318 9e-86
pir||D75212 asparagine--tRNA ligase (EC 6.1.1.22) PAB2203 - Pyro... 305 8e-82
pir||B71248 asparagine--tRNA ligase (EC 6.1.1.22) - Pyrococcus h... 301 9e-81
pir||T04810 aspartate--tRNA ligase homolog F10M23.210 - Arabidop... 292 5e-78
emb|CAC11659.1| (AL445064) probable asparaginyl--tRNA synthetase... 281 1e-74
gi|4557513 aspartyl-tRNA synthetase [Homo sapiens] >gi|135098|sp... 276 3e-73
gi|6323011 Aspartyl-tRNA synthetase, cytosolic; Dps1p [Saccharom... 275 7e-73
pdb|1ASZ|A Chain A, Aspartyl Trna Synthetase (Asprs) (E.C.6.1.1.... 275 7e-73
pdb|1EOV|A Chain A, Free Aspartyl-Trna Synthetase (Asprs) (E.C. ... 275 7e-73
gi|11429379 aspartyl-tRNA synthetase [Homo sapiens] 275 7e-73
sp|P15178|SYD_RAT ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGA... 275 9e-73
sp|P39772|SYN_BACSU ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRN... 275 9e-73
pir||T40867 aspartate--tRNA ligase (EC 6.1.1.12) [similarity] - ... 273 2e-72
pir||T10672 aspartate--tRNA ligase homolog F6E21.100 - Arabidops... 273 3e-72
gb|AAF58445.1| (AE003820) Aats-asp gene product [Drosophila mela... 265 6e-70
gb|AAD21582.1| (AF113612) aspartyl tRNA synthetase [Drosophila m... 263 3e-69
sp|Q03577|SYD_CAEEL PROBABLE ASPARTYL-TRNA SYNTHETASE (ASPARTATE... 259 6e-68
pir||S71074 asparagine--tRNA ligase (EC 6.1.1.22) asnS2 - Lactob... 254 2e-66
pir||S71072 asparagine--tRNA ligase (EC 6.1.1.22) asnS1 - Lactob... 252 4e-66
sp|P54262|SYN_LACDE ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRN... 252 4e-66
dbj|BAB05415.1| (AP001512) asparaginyl-tRNA synthetase [Bacillus... 250 3e-65
sp|P54263|SYN_THETH ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRN... 228 1e-58
sp|Q19722|SYN_CAEEL PROBABLE ASPARAGINYL-TRNA SYNTHETASE, CYTOPL... 196 4e-49
gb|AAD55420.1|AF181634_1 (AF181634) BcDNA.GH06451 [Drosophila me... 192 8e-48
gi|4758762 asparaginyl-tRNA synthetase [Homo sapiens] >gi|391505... 191 1e-47
gi|11426051 asparaginyl-tRNA synthetase [Homo sapiens] 191 1e-47
sp|P75521|SYN_MYCPN ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRN... 190 2e-47
gi|6321807 Asparaginyl-tRNA synthetase; Ded81p [Saccharomyces ce... 189 6e-47
sp|P47359|SYN_MYCGE ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRN... 189 7e-47
sp|P43829|SYN_HAEIN ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRN... 183 4e-45
pir||A82901 asparaginyl-tRNA synthetase UU365 [imported] - Ureap... 181 1e-44
sp|P10723|SYN_BRUMA ASPARAGINYL-TRNA SYNTHETASE, CYTOPLASMIC (AS... 181 2e-44
sp|P17242|SYN_ECOLI ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRN... 180 3e-44
pir||T39675 asparaginyl-trna synthetase - fission yeast (Schizo... 180 3e-44
emb|CAB91185.1| (AL355921) asparaginyl-trna synthetase, mitochon... 180 4e-44
pir||A28209 60K filarial antigen - nematode (Brugia malayi) >gi|... 179 5e-44
sp|P52276|SYN_SYNY3 PROBABLE ASPARAGINYL-TRNA SYNTHETASE (ASPARA... 178 1e-43
pir||E82217 asparaginyl-tRNA synthetase VC1297 [imported] - Vibr... 178 1e-43
sp|O67589|SYD_AQUAE ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 171 1e-41
emb|CAA10904.1| (AJ222644) asparaginyl-tRNA synthetase [Arabidop... 171 2e-41
sp|O51128|SYN_BORBU ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRN... 168 2e-40
pir||F82540 asparaginyl-tRNA synthetase XF2563 [imported] - Xyle... 166 6e-40
sp|O32038|SYD_BACSU ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 160 3e-38
sp|P56459|SYD_HELPY ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 159 8e-38
sp|P57441|SYN_BUCAI ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRN... 157 2e-37
sp|Q9X1F4|SYD_THEMA ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 157 2e-37
sp|Q9ZLL9|SYD_HELPJ ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 155 7e-37
sp|P36419|SYD_THETH ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 153 3e-36
sp|O83618|SYN_TREPA ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRN... 151 1e-35
pir||H82627 aspartyl-tRNA synthetase XF1856 [imported] - Xylella... 150 2e-35
pir||H71612 asparagine--tRNA ligase (EC 6.1.1.22) (OO, TP) PFB05... 150 2e-35
gb|AAD46681.1|AF170909_1 (AF170909) SYNC1 protein [Arabidopsis t... 148 1e-34
pir||E83524 aspartyl-tRNA synthetase PA0963 [imported] - Pseudom... 148 2e-34
dbj|BAB04971.1| (AP001511) aspartyl-tRNA synthetase [Bacillus ha... 146 3e-34
sp|P41255|SYK_THETH LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 146 4e-34
pir||D82910 aspartyl-tRNA synthetase UU286 [imported] - Ureaplas... 143 3e-33
gi|6319872 Asn-tRNA synthetase; Ycr024cp [Saccharomyces cerevisi... 142 9e-33
gb|AAD55509.1|AC008148_19 (AC008148) Similar to asparaginyl-tRN... 141 1e-32
sp|P73443|SYK_SYNY3 LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 140 3e-32
sp|P56126|SYK_HELPY LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 140 3e-32
pir||D75406 aspartyl-tRNA synthetase, discriminating - Deinococc... 140 3e-32
pir||D83183 lysyl-tRNA synthetase PA3700 [imported] - Pseudomona... 140 3e-32
sp|O87821|SYK_RHIME LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 139 4e-32
sp|P73851|SYD_SYNY3 ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 139 4e-32
gb|AAF57921.1| (AE003804) CG6796 gene product [Drosophila melano... 139 6e-32
sp|P75068|SYD_MYCPN ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 138 1e-31
pir||A42609 lysine--tRNA ligase (EC 6.1.1.6) - Campylobacter jej... 137 3e-31
sp|P41258|SYK_CAMJE LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 137 3e-31
sp|P57512|SYK_BUCAI LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 137 3e-31
dbj|BAB15655.1| (AK027094) unnamed protein product [Homo sapiens] 137 3e-31
pir||F82234 aspartyl-tRNA synthetase VC1166 [imported] - Vibrio ... 136 4e-31
sp|P14825|SYK2_ECOLI LYSYL-TRNA SYNTHETASE, HEAT INDUCIBLE (LYSI... 136 6e-31
pdb|1E1O|A Chain A, Lysyl-Trna Synthetase (Lysu) Hexagonal For, ... 136 6e-31
sp|O67258|SYK_AQUAE LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 134 2e-30
sp|P47282|SYD_MYCGE ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 134 3e-30
sp|Q9ZMP8|SYK_HELPJ LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 134 3e-30
pir||G81412 aspartate--tRNA ligase (EC 6.1.1.12) Cj0640c [import... 134 3e-30
gb|AAK40448.1| Lysyl-tRNA synthetase (lysS) [Sulfolobus solfatar... 132 6e-30
sp|P95970|SYK_SULSO LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 132 6e-30
sp|P43825|SYK_HAEIN LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 132 7e-30
pir||G81195 aspartyl-tRNA synthetase NMB0466 [imported] - Neisse... 132 1e-29
sp|P13030|SYK1_ECOLI LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE)... 131 1e-29
sp|Q9KGG4|SYK_BACHD LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 131 1e-29
pdb|1BBU|A Chain A, Lysyl-Trna Synthetase (Lyss) Complexed With ... 131 1e-29
emb|CAC11748.1| (AL445064) asparagine--tRNA ligase related prote... 131 2e-29
sp|Q9RHV9|SYK_BACST LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 131 2e-29
pir||F81831 aspartate--tRNA ligase (EC 6.1.1.12) NMA2019 [import... 131 2e-29
pir||JC7205 lysine-tRNA ligase (AMP forming) (EC 6.1.1.6) - Baci... 131 2e-29
emb|CAC08476.1| (AL392189) aspartyl-tRNA synthetase [Streptomyce... 130 3e-29
sp|P37477|SYK_BACSU LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 130 4e-29
sp|Q53638|SYK_STAAU LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 130 4e-29
pir||S77851 probable aspartate--tRNA ligase (EC 6.1.1.12) - Myco... 129 6e-29
sp|Q9X231|SYK_THEMA LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 128 1e-28
pir||E81660 aspartyl-tRNA synthetase TC0829 [imported] - Chlamyd... 128 1e-28
sp|Q43990|SYK_ACICA LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 127 2e-28
sp|P43817|SYD_HAEIN ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 127 2e-28
sp|Q9ZE17|SYD_RICPR ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 126 6e-28
gb|AAF46510.1| (AE003447) CG12141 gene product [Drosophila melan... 126 6e-28
pir||B81858 lysine--tRNA ligase (EC 6.1.1.6) NMA1638 [imported] ... 126 6e-28
sp|Q49158|SYK_MYCFE LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 125 1e-27
sp|O84546|SYD_CHLTR ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 125 1e-27
pir||C81086 lysyl-tRNA synthetase, heat inducible NMB1425 [impor... 125 1e-27
sp|P21889|SYD_ECOLI ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 122 6e-27
sp|O83950|SYD_TREPA ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 122 6e-27
pdb|1C0A|A Chain A, Crystal Structure Of The E. Coli Aspartyl-Tr... 122 6e-27
sp|P57401|SYD_BUCAI ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 122 6e-27
sp|Q50649|SYD_MYCTU ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 121 1e-26
sp|Q9Z7P2|SYD_CHLPN ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 120 3e-26
sp|O51402|SYD_BORBU ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 120 4e-26
sp|Q9PEB6|SYK_XYLFA LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 119 7e-26
gb|AAA24096.1| (M30630) lysyl-tRNA synthetase (lysU) (E.C. 6.1.1... 118 1e-25
sp|P36429|SYD_MYCLE ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 118 2e-25
pir||S69892 lysine--tRNA ligase (EC 6.1.1.6) - Mycoplasma hominis 116 4e-25
sp|P37879|SYK_CRILO LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 116 4e-25
dbj|BAA06688.1| (D31890) similar to lysyl tRNA synthetase. [Homo... 116 6e-25
gi|5031815 lysyl-tRNA synthetase; lysine tRNA ligase [Homo sapie... 116 6e-25
sp|Q15046|SYK_HUMAN LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 116 6e-25
gb|AAG30114.1|AF285758_1 (AF285758) lysyl-tRNA synthetase [Homo ... 116 6e-25
sp|P81432|SYD_BUCAP ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LI... 115 8e-25
sp|Q22099|SYK_CAEEL PROBABLE LYSYL-TRNA SYNTHETASE (LYSINE--TRNA... 114 2e-24
emb|CAA39699.1| (X56259) lysine--tRNA ligase [Saccharomyces cere... 114 2e-24
gi|6320242 lysyl-tRNA synthetase; Krs1p [Saccharomyces cerevisia... 113 3e-24
sp|Q9PR83|SYK_UREPA LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 113 4e-24
sp|P46191|SYK_MYCHO LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 112 7e-24
dbj|BAA35676.1| (D90730) Asparaginyl-tRNA synthetase (EC 6.1.1.... 112 7e-24
emb|CAA10905.1| (AJ222645) asparaginyl-tRNA synthetase [Arabidop... 111 1e-23
gb|AAD46682.1|AF170910_1 (AF170910) SYNC2 protein [Arabidopsis t... 111 1e-23
gb|AAF02166.1|AC009853_26 (AC009853) putative asparaginyl-tRNA s... 111 1e-23
pir||T04993 probable aspartate--tRNA ligase (EC 6.1.1.12) T16L1.... 110 3e-23
emb|CAB89697.1| (AJ276418) putative lysyl tRNA synthetase [Xanth... 110 4e-23
sp|Q9KU60|SYK_VIBCH LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 109 5e-23
gb|AAF53577.2| (AE003652) CG17938 gene product [Drosophila melan... 107 3e-22
sp|P47382|SYK_MYCGE LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 106 7e-22
pir||S70779 asparagine--tRNA ligase (EC 6.1.1.22) - Xenorhabdus ... 99 9e-20
dbj|BAA99139.1| (AP002548) lysyl tRNA synthetase [Chlamydophila ... 98 2e-19
sp|Q9Z6X5|SYK_CHLPN LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) ... 98 3e-19
pir||T41563 hypothetical protein SPCC736.06 - fission yeast (Sc... 96 8e-19
pir||E70155 aspartate--tRNA ligase (EC 6.1.1.12) aspS - Lyme dis... 91 2e-17
pir||S77842 probable asparagine--tRNA ligase (EC 6.1.1.22) - Myc... 89 8e-17
gi|6325153 Aspartyl-tRNA synthetase, mitochondrial; Msd1p [Sacch... 89 1e-16
dbj|BAA90843.1| (AB031211) LysS [Bacillus halodurans] 85 2e-15
sp|Q56112|SYN_SALTI ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRN... 83 6e-15
pir||C75215 asparaginyl-tRNA synthetase related protein PAB2356 ... 75 1e-12
pir||E82050 lysyl-tRNA synthetase-related protein VC2655 [import... 71 2e-11
sp|Q9Z614|SYK3_BUCAP PUTATIVE LYSYL-TRNA SYNTHETASE (LYSINE--TRN... 70 4e-11
gb|AAD12351.1| (U01814) unknown [Mycoplasma genitalium] 69 7e-11
>pir||A75071 aspartyl-tRNA synthetase (asps) PAB0646 - Pyrococcus abyssi
(strain Orsay) >gi|5458382|emb|CAB49870.1| (AJ248286)
aspartyl-tRNA synthetase (aspS) [Pyrococcus abyssi]
Length = 438
Score = 889 bits (2271), Expect = 0.0
Identities = 438/438 (100%), Positives = 438/438 (100%)
Query: 1 MLRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF 60
MLRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF
Sbjct: 1 MLRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF 60
Query: 61 KLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTR 120
KLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTR
Sbjct: 61 KLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTR 120
Query: 121 LDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKY 180
LDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKY
Sbjct: 121 LDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKY 180
Query: 181 FENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESE 240
FENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESE
Sbjct: 181 FENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESE 240
Query: 241 EEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIP 300
EEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIP
Sbjct: 241 EEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIP 300
Query: 301 WGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGV 360
WGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGV
Sbjct: 301 WGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGV 360
Query: 361 EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDI 420
EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDI
Sbjct: 361 EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDI 420
Query: 421 GNIREVILFPRDRRRLVP 438
GNIREVILFPRDRRRLVP
Sbjct: 421 GNIREVILFPRDRRRLVP 438
>sp|O58776|SYD_PYRHO ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|7437590|pir||G71094 aspartate--tRNA ligase (EC
6.1.1.12) - Pyrococcus horikoshii
>gi|3257434|dbj|BAA30117.1| (AP000004) 438aa long
hypothetical aspartyl-tRNA synthetase [Pyrococcus
horikoshii]
Length = 438
Score = 844 bits (2157), Expect = 0.0
Identities = 409/438 (93%), Positives = 429/438 (97%)
Query: 1 MLRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF 60
MLRTHYS+EITEELNGK+VKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKV QEIF
Sbjct: 1 MLRTHYSNEITEELNGKRVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVSQEIF 60
Query: 61 KLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTR 120
KLIPKLNSEDVIVVEGIVNFTPKAKLGFE+IPEKLEVIS+AKTPLPLDPTGKVKAELDTR
Sbjct: 61 KLIPKLNSEDVIVVEGIVNFTPKAKLGFEVIPEKLEVISRAKTPLPLDPTGKVKAELDTR 120
Query: 121 LDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKY 180
LDNRFMDLRNP+VM+IFKIRSSVFRA REFFY EGFIEIHTPKIIATATEGGTELFPLKY
Sbjct: 121 LDNRFMDLRNPKVMAIFKIRSSVFRAVREFFYSEGFIEIHTPKIIATATEGGTELFPLKY 180
Query: 181 FENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESE 240
FE DAFLAQSPQLYKQMMM+TGLDKVFEI PIFRAEEHNTTRHLNEAWSIDAEMAFIE+E
Sbjct: 181 FERDAFLAQSPQLYKQMMMATGLDKVFEIAPIFRAEEHNTTRHLNEAWSIDAEMAFIENE 240
Query: 241 EEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIP 300
EVMDLLERLI YVINYVRE+NEKELK LEFELNEPK+PFPRITYD+ALEILSDLGKEIP
Sbjct: 241 GEVMDLLERLISYVINYVREHNEKELKTLEFELNEPKRPFPRITYDKALEILSDLGKEIP 300
Query: 301 WGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGV 360
WGEDIDTEGEKLLGKYM ENEGA+LYFIYRYPSEAKPFYIMKY++KPEVC+AFDLEYRGV
Sbjct: 301 WGEDIDTEGEKLLGKYMAENEGADLYFIYRYPSEAKPFYIMKYDEKPEVCRAFDLEYRGV 360
Query: 361 EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDI 420
EISSGGQREHRHD+L+EQI+EKGLNP+SFEFYL+AFEYGMPPHGGFGLGAERLIMRMLDI
Sbjct: 361 EISSGGQREHRHDVLLEQIKEKGLNPKSFEFYLKAFEYGMPPHGGFGLGAERLIMRMLDI 420
Query: 421 GNIREVILFPRDRRRLVP 438
GNIREVILFPRDRRRLVP
Sbjct: 421 GNIREVILFPRDRRRLVP 438
>sp|Q52428|SYD_PYRKO ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|2129413|pir||JC4352 aspartate--tRNA ligase (EC
6.1.1.12) - Pyrococcus sp >gi|1136773|dbj|BAA08115.1|
(D45167) aspartyl-tRNA synthetase [Pyrococcus sp.]
Length = 438
Score = 773 bits (1975), Expect = 0.0
Identities = 364/438 (83%), Positives = 408/438 (93%)
Query: 1 MLRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF 60
M RTHYSSEITEELNG+KVKVAGWV EVKDLGGIKF+WIRDR+GIVQ+TAPKKKV E+F
Sbjct: 1 MYRTHYSSEITEELNGQKVKVAGWVWEVKDLGGIKFLWIRDRDGIVQITAPKKKVDPELF 60
Query: 61 KLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTR 120
KLIPKL SEDV+ VEG+VNFTPKAKLGFEI+PEK+ V+++A+TPLPLDPTGKVKAELDTR
Sbjct: 61 KLIPKLRSEDVVAVEGVVNFTPKAKLGFEILPEKIVVLNRAETPLPLDPTGKVKAELDTR 120
Query: 121 LDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKY 180
LDNRFMDLR P VM+IFKIRSSVF+A R+FF++ GFIEIHTPKIIATATEGGTELFP+KY
Sbjct: 121 LDNRFMDLRRPEVMAIFKIRSSVFKAVRDFFHENGFIEIHTPKIIATATEGGTELFPMKY 180
Query: 181 FENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESE 240
FE DAFLAQSPQLYKQ+MM++GLD+V+EI PIFRAEEHNTTRHLNEAWSID+EMAFIE E
Sbjct: 181 FEEDAFLAQSPQLYKQIMMASGLDRVYEIAPIFRAEEHNTTRHLNEAWSIDSEMAFIEDE 240
Query: 241 EEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIP 300
EEVM LERL+ + INYVRE+N KEL IL FEL EPK PFPR++YD+ALEIL DLGKEIP
Sbjct: 241 EEVMSFLERLVAHAINYVREHNAKELDILNFELEEPKLPFPRVSYDKALEILGDLGKEIP 300
Query: 301 WGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGV 360
WGEDIDTEGE+LLGKYM+ENE A LYF+Y+YPSEAKPFYIMKY++KPE+C+AFDLEYRGV
Sbjct: 301 WGEDIDTEGERLLGKYMMENENAPLYFLYQYPSEAKPFYIMKYDNKPEICRAFDLEYRGV 360
Query: 361 EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDI 420
EISSGGQREHRHDILVEQI+EKGLNPESFEFYL+AF YGMPPHGGFGLGAER+I +MLD+
Sbjct: 361 EISSGGQREHRHDILVEQIKEKGLNPESFEFYLKAFRYGMPPHGGFGLGAERVIKQMLDL 420
Query: 421 GNIREVILFPRDRRRLVP 438
NIREVILFPRDRRRL P
Sbjct: 421 PNIREVILFPRDRRRLTP 438
>pdb|1B8A|A Chain A, Aspartyl-Trna Synthetase >gi|4388837|pdb|1B8A|B Chain B,
Aspartyl-Trna Synthetase
Length = 438
Score = 770 bits (1967), Expect = 0.0
Identities = 362/438 (82%), Positives = 408/438 (92%)
Query: 1 MLRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF 60
M RTHYSSEITEELNG+KVKVAGWV EVKDLGGIKF+WIRDR+GIVQ+TAPKKKV E+F
Sbjct: 1 MYRTHYSSEITEELNGQKVKVAGWVWEVKDLGGIKFLWIRDRDGIVQITAPKKKVDPELF 60
Query: 61 KLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTR 120
KLIPKL SEDV+ VEG+VNFTPKAKLGFEI+PEK+ V+++A+TPLPLDPTGKVKAELDTR
Sbjct: 61 KLIPKLRSEDVVAVEGVVNFTPKAKLGFEILPEKIVVLNRAETPLPLDPTGKVKAELDTR 120
Query: 121 LDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKY 180
L+NRFMDLR P VM+IFKIRSSVF+A R+FF++ GFIEIHTPKIIATATEGGTELFP+KY
Sbjct: 121 LNNRFMDLRRPEVMAIFKIRSSVFKAVRDFFHENGFIEIHTPKIIATATEGGTELFPMKY 180
Query: 181 FENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESE 240
FE DAFLA+SPQLYK++MM++GLD+V+EI PIFRAEEHNTTRHLNEAWSID+EMAFIE E
Sbjct: 181 FEEDAFLAESPQLYKEIMMASGLDRVYEIAPIFRAEEHNTTRHLNEAWSIDSEMAFIEDE 240
Query: 241 EEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIP 300
EEVM LERL+ + INYVRE+N KEL IL FEL EPK PFPR++YD+ALEIL DLGKEIP
Sbjct: 241 EEVMSFLERLVAHAINYVREHNAKELDILNFELEEPKLPFPRVSYDKALEILGDLGKEIP 300
Query: 301 WGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGV 360
WGEDIDTEGE+LLGKYM+ENE A LYF+Y+YPSEAKPFYIMKY++KPE+C+AFDLEYRGV
Sbjct: 301 WGEDIDTEGERLLGKYMMENENAPLYFLYQYPSEAKPFYIMKYDNKPEICRAFDLEYRGV 360
Query: 361 EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDI 420
EISSGGQREHRHDILVEQI+EKGLNPESFEFYL+AF YGMPPHGGFGLGAERLI +MLD+
Sbjct: 361 EISSGGQREHRHDILVEQIKEKGLNPESFEFYLKAFRYGMPPHGGFGLGAERLIKQMLDL 420
Query: 421 GNIREVILFPRDRRRLVP 438
NIREVILFPRDRRRL P
Sbjct: 421 PNIREVILFPRDRRRLTP 438
>gi|11498525 aspartyl-tRNA synthetase (aspS) [Archaeoglobus fulgidus]
>gi|3122883|sp|O29342|SYD_ARCFU ASPARTYL-TRNA SYNTHETASE
(ASPARTATE--TRNA LIGASE) (ASPRS) >gi|7437591|pir||H69364
aspartyl-tRNA synthetase (aspS) homolog - Archaeoglobus
fulgidus >gi|2649677|gb|AAB90318.1| (AE001040)
aspartyl-tRNA synthetase (aspS) [Archaeoglobus fulgidus]
Length = 430
Score = 527 bits (1344), Expect = e-149
Identities = 262/433 (60%), Positives = 326/433 (74%), Gaps = 6/433 (1%)
Query: 6 YSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPK 65
Y++++ E+ G+KV + GWV EV+DLGG+ FI +RDREGIVQ+T P+K V +++FKL K
Sbjct: 4 YTADVKPEMEGQKVTLYGWVHEVRDLGGLVFILLRDREGIVQITLPRKFVSKQVFKLAKK 63
Query: 66 LNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRF 125
+ E VI V G V KA G EIIPE +EV+++A PLPL+ T KV AELDTRLD+RF
Sbjct: 64 IRRESVIAVTGEVRREEKAPGGVEIIPESIEVLNEADAPLPLEVTEKVPAELDTRLDHRF 123
Query: 126 MDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDA 185
MDLR PRV +IF+IR V ++ REF +EGFIE+HTPKI++TATEGGTELFP+ YFE +A
Sbjct: 124 MDLRRPRVQAIFRIRHQVMQSVREFLSEEGFIEVHTPKIVSTATEGGTELFPISYFEKEA 183
Query: 186 FLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMD 245
FL QSPQLYKQ++M+ G +KVFEIGPIFRAEEHNTTRHLNEA SID EM+F + VMD
Sbjct: 184 FLNQSPQLYKQVLMAAGFEKVFEIGPIFRAEEHNTTRHLNEAISIDIEMSFTD-HNGVMD 242
Query: 246 LLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIPWGEDI 305
+LERL+ V V E E+ L LE L P+ PFPRITYDEA EI + G+EIPWGED+
Sbjct: 243 VLERLVQRVYEDVAEKCERYLGWLEVSLEIPELPFPRITYDEAREIAARKGEEIPWGEDL 302
Query: 306 DTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSG 365
T KL+G+ M LYFI +P+E+KPFY M YED+PE+ K+FDL + +E+SSG
Sbjct: 303 STNALKLVGEEM-----GGLYFITDWPTESKPFYAMPYEDRPEISKSFDLMHGWLELSSG 357
Query: 366 GQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIRE 425
QR H +D+LVE I+ KG+ PESF FYL AF YGMPPH G+GLGAERLIM ML + N+RE
Sbjct: 358 AQRIHLYDMLVESIKAKGMEPESFGFYLEAFRYGMPPHAGWGLGAERLIMSMLGLKNVRE 417
Query: 426 VILFPRDRRRLVP 438
+LFPRDR RLVP
Sbjct: 418 AVLFPRDRHRLVP 430
>sp|Q58950|SYD_METJA ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|2127776|pir||B64494 aspartate--tRNA ligase (EC
6.1.1.12) - Methanococcus jannaschii
>gi|1592183|gb|AAB99575.1| (U67596) aspartyl-tRNA
synthetase (aspS) [Methanococcus jannaschii]
Length = 438
Score = 514 bits (1310), Expect = e-145
Identities = 253/436 (58%), Positives = 324/436 (74%), Gaps = 6/436 (1%)
Query: 3 RTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKL 62
RTHYS++I E++G++V + GWV ++ LG I F+ +RDREG VQ+ APK+KV E+F
Sbjct: 9 RTHYSADIKPEMDGQEVIIMGWVHSIRALGKIIFVILRDREGTVQIVAPKQKVGDELFSQ 68
Query: 63 IPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLD 122
I KL +EDVI V+G V KA GFEI+P +LEVI+ AK PLPLDP KV AELDTRL+
Sbjct: 69 IKKLGAEDVIAVKGKVIANEKAPNGFEILPLELEVINTAKRPLPLDPAEKVPAELDTRLE 128
Query: 123 NRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFE 182
NRF+DLR P+V +IFKIRS + ++ R Y EGFIE++TPK++A+ TEGGTELFP+ YFE
Sbjct: 129 NRFLDLRRPKVQAIFKIRSEMLKSVRNTLYNEGFIEVNTPKLVASCTEGGTELFPISYFE 188
Query: 183 NDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEE 242
+AFL QSPQLYKQM+M+TGLD+VFEI PIFRAEEHNT RHLNEA SID EMAF + +++
Sbjct: 189 REAFLGQSPQLYKQMLMATGLDRVFEIAPIFRAEEHNTRRHLNEATSIDIEMAFAD-DKD 247
Query: 243 VMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIPWG 302
MD+LE+++ V EN +KE++ L E P + F RITYDEA++I + G EI WG
Sbjct: 248 AMDILEKVVYNAFVDVYENRKKEIETLGIEFELPPEKFDRITYDEAIDIANAKGVEISWG 307
Query: 303 EDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEI 362
ED+ E EK +G+ E EG LYFI +PSE +PFY M E P +CKAFDL Y+ +EI
Sbjct: 308 EDLSREAEKAIGE---EMEG--LYFITDWPSEIRPFYTMPDEKNPNICKAFDLMYKDLEI 362
Query: 363 SSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGN 422
SSG QR H +D+LVE I++KGLNP+ F +YL AF+YGMPPH G+GLGA+R M + N
Sbjct: 363 SSGAQRIHLYDLLVENIKKKGLNPDGFTYYLEAFKYGMPPHAGWGLGADRFTMVLTQQEN 422
Query: 423 IREVILFPRDRRRLVP 438
IRE +LFPRDR+RL P
Sbjct: 423 IRECVLFPRDRQRLTP 438
>sp|O26328|SYD_METTH ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|7437592|pir||A69128 aspartate--tRNA ligase (EC
6.1.1.12) - Methanobacterium thermoautotrophicum (strain
Delta H) >gi|2621273|gb|AAB84732.1| (AE000809)
aspartyl-tRNA synthetase [Methanobacterium
thermoautotrophicum]
Length = 437
Score = 495 bits (1262), Expect = e-139
Identities = 246/436 (56%), Positives = 320/436 (72%), Gaps = 6/436 (1%)
Query: 3 RTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKL 62
RTHYS +I E++G +V V GWV E++DLGGI F+ +RDR+G++Q+TAP KK+ +++FK
Sbjct: 8 RTHYSKDIEPEMDGDEVTVMGWVHEIRDLGGIIFVLLRDRDGLIQITAPSKKIEKDLFKS 67
Query: 63 IPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLD 122
I KL E V+ G V + KA GFEIIP L+V++ +K PLPLDPT KVKAE+DTRLD
Sbjct: 68 IRKLKKESVVAFGGTVQESGKAPGGFEIIPSFLKVLNISKQPLPLDPTEKVKAEIDTRLD 127
Query: 123 NRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFE 182
RF+DLR P V +IFKI+S + + R F ++GF+EI+TPK++A+ATEGGTELFP+ YFE
Sbjct: 128 ARFLDLRKPSVSAIFKIKSRMLHSVRVFLEEQGFLEINTPKLVASATEGGTELFPITYFE 187
Query: 183 NDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEE 242
+AFL QSPQLYKQ+MMSTGLD+V+EI PIFRAEEH+T RHLNE SID E +F++ E+
Sbjct: 188 REAFLGQSPQLYKQIMMSTGLDRVYEIAPIFRAEEHDTLRHLNEVISIDIEASFVD-HED 246
Query: 243 VMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIPWG 302
VM +LE L++ VI V E+ L+ L L P+ PF R+ YDEA+E+++ G + G
Sbjct: 247 VMKILENLVVRVIEDVNEHCTDALETLGRTLEVPETPFERLEYDEAVEMVNSKGVPMKHG 306
Query: 303 EDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEI 362
ED+ EK LG+ M +G YFI +P+ KPFY+M ED PE AFDL YR +EI
Sbjct: 307 EDLPRAAEKALGEIM---DG--YYFITSWPTAIKPFYVMPDEDDPERSHAFDLMYRDLEI 361
Query: 363 SSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGN 422
SSG R H+HD+LVE+I+ +GLNP+SFE YL AFEYGMPPH G+GLGAER M + + N
Sbjct: 362 SSGAMRVHQHDLLVEKIKRQGLNPDSFESYLSAFEYGMPPHAGWGLGAERFNMTLTGLKN 421
Query: 423 IREVILFPRDRRRLVP 438
IRE +LFPRDRRRL P
Sbjct: 422 IRETVLFPRDRRRLTP 437
>sp|O24822|SYD_HALVO ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|3298338|dbj|BAA31457.1| (AB010464) aspartyl tRNA
synthetase [Haloferax volcanii]
Length = 433
Score = 412 bits (1048), Expect = e-114
Identities = 217/428 (50%), Positives = 289/428 (66%), Gaps = 12/428 (2%)
Query: 16 GKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVE 75
G V VAGWV EV+DLGGI F+ +RD G +QV K ++ ++ + ++ E VI V
Sbjct: 13 GDTVTVAGWVHEVRDLGGIAFLILRDTSGKIQVKFEKDEMDDDLVETGLGVHRESVISVT 72
Query: 76 GIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPRVMS 135
G V+ P+A G E+ PE L+VI++A+ LPLDP+GKV AEL TRLDNR +DLR V +
Sbjct: 73 GEVDEEPRAPTGVEVTPESLDVIAEAEAQLPLDPSGKVDAELSTRLDNRTLDLRKDEVKA 132
Query: 136 IFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFLAQSPQLYK 195
IF+IR+ V RA R+ F EI+TPKI+AT TEGGTELFP+ YF +AF+ QSPQL+K
Sbjct: 133 IFEIRAEVQRAVRDKFRDLRATEINTPKIVATGTEGGTELFPITYFGQEAFMNQSPQLFK 192
Query: 196 QMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYVI 255
Q+M+ +GL++VFE+GPIFRAEEHNT RHLNEA SID E AFI+ E MD+ E ++
Sbjct: 193 QLMVGSGLERVFEVGPIFRAEEHNTPRHLNEATSIDFESAFID-HTEAMDVCEAVVTAAY 251
Query: 256 NYVRENNEKELKIL----EFELNEPKKPFPRIT-YDEALEILSDLGKEIPWGEDIDTEGE 310
V EN + EL+ L EFE P+ P + A + +L +++ WG+D+ TEGE
Sbjct: 252 EAVEENCQDELEALGLEEEFE-RRPRVPAAHLRGGHRAHQRTGELDEQLVWGDDLPTEGE 310
Query: 311 KLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSGGQREH 370
K LG+ + E YFI +PSE KPFYI ++D + FD+ + +E+ SGGQREH
Sbjct: 311 KALGE-----DVGEHYFITDWPSEIKPFYIKDHDDDETLSTGFDMMHPNMELVSGGQREH 365
Query: 371 RHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFP 430
R D LV ++GL+P++FE+Y + F+YGMPPH GFGLG ERLIM ML + NIRE +LFP
Sbjct: 366 RFDHLVAGFEQQGLDPDAFEYYTKMFKYGMPPHAGFGLGGERLIMTMLGLENIREAVLFP 425
Query: 431 RDRRRLVP 438
RDR+RL P
Sbjct: 426 RDRQRLSP 433
>sp|Q9Y9U7|SYD_AERPE ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
Length = 442
Score = 404 bits (1028), Expect = e-112
Identities = 198/443 (44%), Positives = 294/443 (65%), Gaps = 6/443 (1%)
Query: 1 MLRTHYSSEIT---EELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQ 57
ML+ + ++I E L G +V+V GW ++DLG +KFI +RDR G++Q T + + P+
Sbjct: 1 MLKDRFIADIIASKESLVGGRVRVCGWAYRIRDLGRLKFILVRDRSGVIQATVKRGESPE 60
Query: 58 EIFKLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAEL 117
+ + L E V+ VEG + P + G E+ E+LEV+S PLPL+ G KA L
Sbjct: 61 DALRAAEDLKLESVVCVEGELRQAPTRE-GVEVKVERLEVLSTPVEPLPLEVEGSEKASL 119
Query: 118 DTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFP 177
TRL R++D+RNP V +IF++ + V + R++++ +GF+EI TPKI+A TE G E+FP
Sbjct: 120 PTRLKYRWLDIRNPMVSAIFELEAMVAKVFRDYYWSQGFVEIFTPKIVAAGTESGAEVFP 179
Query: 178 LKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFI 237
+ YF+ AFLAQSPQ YKQ + GL++VFEIGP+FRAE H+T+RHLNE S+D E+ FI
Sbjct: 180 VVYFDKTAFLAQSPQFYKQFAVIAGLERVFEIGPVFRAEPHHTSRHLNEYHSLDIEVGFI 239
Query: 238 ESEEEVMDLLERLILYVINYVRENNEKELKILEFELNE-PKKPFPRITYDEALEILSD-L 295
ES +VM+ +E + ++ + E+ + L++ EL P P+I +A EIL +
Sbjct: 240 ESYNDVMNYVEGFMRAIVRMLEEDGRRVLELYGVELPRIPASGIPKIPLRKAYEILEEKY 299
Query: 296 GKEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDL 355
GK++ +GED+D+EGE+L+G Y E ++ FI YP + +PFY M+ +D+P +FDL
Sbjct: 300 GKKVEYGEDLDSEGERLMGAYAGEELDSDFVFIVEYPWKVRPFYTMRKDDEPSWTYSFDL 359
Query: 356 EYRGVEISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIM 415
YRG+EI +GGQREHR+ L+E +R+KGL+ ESF+FYL F++G PPHGG G+G ER++M
Sbjct: 360 LYRGLEIVTGGQREHRYHRLLENLRDKGLDAESFQFYLDFFKHGAPPHGGAGMGLERIVM 419
Query: 416 RMLDIGNIREVILFPRDRRRLVP 438
+ L + NIRE + PRD R+ P
Sbjct: 420 QTLKLENIREARMLPRDTERITP 442
>pir||C72527 probable aspartyl-tRNA synthetase APE2192 - Aeropyrum pernix
(strain K1) >gi|5105891|dbj|BAA81203.1| (AP000063) 421aa
long hypothetical aspartyl-tRNA synthetase [Aeropyrum
pernix]
Length = 421
Score = 397 bits (1010), Expect = e-109
Identities = 191/422 (45%), Positives = 283/422 (66%), Gaps = 3/422 (0%)
Query: 19 VKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVEGIV 78
++V GW ++DLG +KFI +RDR G++Q T + + P++ + L E V+ VEG +
Sbjct: 1 MRVCGWAYRIRDLGRLKFILVRDRSGVIQATVKRGESPEDALRAAEDLKLESVVCVEGEL 60
Query: 79 NFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPRVMSIFK 138
P + G E+ E+LEV+S PLPL+ G KA L TRL R++D+RNP V +IF+
Sbjct: 61 RQAPTRE-GVEVKVERLEVLSTPVEPLPLEVEGSEKASLPTRLKYRWLDIRNPMVSAIFE 119
Query: 139 IRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFLAQSPQLYKQMM 198
+ + V + R++++ +GF+EI TPKI+A TE G E+FP+ YF+ AFLAQSPQ YKQ
Sbjct: 120 LEAMVAKVFRDYYWSQGFVEIFTPKIVAAGTESGAEVFPVVYFDKTAFLAQSPQFYKQFA 179
Query: 199 MSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYVINYV 258
+ GL++VFEIGP+FRAE H+T+RHLNE S+D E+ FIES +VM+ +E + ++ +
Sbjct: 180 VIAGLERVFEIGPVFRAEPHHTSRHLNEYHSLDIEVGFIESYNDVMNYVEGFMRAIVRML 239
Query: 259 RENNEKELKILEFELNE-PKKPFPRITYDEALEILSD-LGKEIPWGEDIDTEGEKLLGKY 316
E+ + L++ EL P P+I +A EIL + GK++ +GED+D+EGE+L+G Y
Sbjct: 240 EEDGRRVLELYGVELPRIPASGIPKIPLRKAYEILEEKYGKKVEYGEDLDSEGERLMGAY 299
Query: 317 MLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSGGQREHRHDILV 376
E ++ FI YP + +PFY M+ +D+P +FDL YRG+EI +GGQREHR+ L+
Sbjct: 300 AGEELDSDFVFIVEYPWKVRPFYTMRKDDEPSWTYSFDLLYRGLEIVTGGQREHRYHRLL 359
Query: 377 EQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRRRL 436
E +R+KGL+ ESF+FYL F++G PPHGG G+G ER++M+ L + NIRE + PRD R+
Sbjct: 360 ENLRDKGLDAESFQFYLDFFKHGAPPHGGAGMGLERIVMQTLKLENIREARMLPRDTERI 419
Query: 437 VP 438
P
Sbjct: 420 TP 421
>emb|CAC12075.1| (AL445066) aspartyl-tRNA synthetase related protein [Thermoplasma
acidophilum]
Length = 428
Score = 390 bits (991), Expect = e-107
Identities = 194/434 (44%), Positives = 286/434 (65%), Gaps = 11/434 (2%)
Query: 6 YSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPK 65
Y + + +G KV V GW+QE + + I F+ IRD G +Q T + +I K +
Sbjct: 5 YIDTLRDHEDGAKVVVYGWMQEARIMKNISFLMIRDNTGTIQATFKNDEATLDIIK---R 61
Query: 66 LNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRF 125
+N E ++ V+G VN +K G EI + ++++A+ PLPL V+A+L+TRL++RF
Sbjct: 62 INRESIVRVDGSVNKKSISKAGIEISGTSISIVNEAEAPLPLPVVDPVQADLETRLNSRF 121
Query: 126 MDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDA 185
MDLR + +IF+I S++ R++ + + FIE+HTPKI+A ATEGG++LFP++YFE DA
Sbjct: 122 MDLRKRNISAIFRIESALLWGIRQYLHSQKFIEVHTPKIVAAATEGGSDLFPVRYFEKDA 181
Query: 186 FLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMD 245
+L QSPQLYK+++MS G D+VFE+GP FRAEEHNTTRHLNE SID EM+F + + M
Sbjct: 182 YLNQSPQLYKEVLMSAGFDRVFEVGPAFRAEEHNTTRHLNEFTSIDIEMSFAD-HNDAMA 240
Query: 246 LLERLILYVI-NYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIPWGED 304
+LE I I N VREN E + + L ++ P+ PFPRITY++ +++L G + +G+D
Sbjct: 241 MLENAIRSGIENAVRENAE-DFESLGISISVPETPFPRITYEQCIDLLQKDGIDFTFGDD 299
Query: 305 IDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISS 364
+ + +G + + YFI +PS +PFY M + P + +FDL+YR +E++S
Sbjct: 300 FSPDQLRTIG-----SRFSGFYFITEWPSSVRPFYTMPKSEDPRLTNSFDLQYREIEVTS 354
Query: 365 GGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIR 424
G QR H +L+++ EK L+ +SF+FY+ AF+YGMPPH G+GLG ERL M +L + NIR
Sbjct: 355 GAQRVHDPKMLIQRFNEKKLDVKSFQFYVDAFKYGMPPHAGWGLGLERLTMILLGLNNIR 414
Query: 425 EVILFPRDRRRLVP 438
E LFPRDR R+VP
Sbjct: 415 ETTLFPRDRTRIVP 428
>gb|AAK40519.1| Aspartyl-tRNA synthetase (aspS) [Sulfolobus solfataricus]
Length = 429
Score = 383 bits (972), Expect = e-105
Identities = 191/438 (43%), Positives = 292/438 (66%), Gaps = 9/438 (2%)
Query: 1 MLRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF 60
M RTH SE+ +L+G +VKVAGWV V++LGG FI +RD+ GI Q+ K +
Sbjct: 1 MFRTHLVSELNPKLDGSEVKVAGWVHNVRNLGGKIFILLRDKSGIGQIVVEKGN---NAY 57
Query: 61 KLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTR 120
+ + E IVV G+V +A G E+ + +E++S A++PLPLD TGKVKA++DTR
Sbjct: 58 DKVINIGLESTIVVNGVVKADARAPNGVEVHAKDIEILSYARSPLPLDVTGKVKADIDTR 117
Query: 121 LDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKY 180
L R +DLR + ++ KI+S ++ RE YK GF+E+ TPKIIA+ATEGG +LFP+ Y
Sbjct: 118 LRERLLDLRRLEMQAVLKIQSVAVKSFRETLYKHGFVEVFTPKIIASATEGGAQLFPVLY 177
Query: 181 FENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESE 240
F +AFLAQSPQLYK+ +++ +++VFEI P +RAEE +T HL+E S+D EMAF +
Sbjct: 178 FGKEAFLAQSPQLYKE-LLAGAIERVFEIAPAWRAEESDTPYHLSEFISMDVEMAFAD-Y 235
Query: 241 EEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIP 300
++M L+E++I +IN V+ E ELKIL + + P +++Y +A+E+L G I
Sbjct: 236 NDIMALIEQIIYNMINDVKRECENELKILNYTPPNVRIPIKKVSYSDAIELLKSKGVNIK 295
Query: 301 WGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGV 360
+G+DI T ++L + E +LYF+ +P ++PFY + +D P++ ++FDL +R +
Sbjct: 296 FGDDIGTPELRVLYNELKE----DLYFVTDWPWLSRPFYTKQKKDNPQLSESFDLIFRWL 351
Query: 361 EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDI 420
EI SG R H ++L ++ +GLNPESFEF+L+ F+YGMPPH GFG+G R+++ + +
Sbjct: 352 EIVSGSSRNHVKEVLENSLKVRGLNPESFEFFLKWFDYGMPPHAGFGMGLARVMLMLTGL 411
Query: 421 GNIREVILFPRDRRRLVP 438
+++EV+ FPRD++RL P
Sbjct: 412 QSVKEVVPFPRDKKRLTP 429
>sp|O07683|SYD_HALSA ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|11271301|pir||T48900 aspartate--tRNA ligase (EC
6.1.1.12) [imported] - Halobacterium salinarum
>gi|2209068|dbj|BAA20527.1| (D82887) aspartyl-tRNA
synthetase [Halobacterium salinarum]
>gi|10580067|gb|AAG19001.1| (AE005000) aspartyl-tRNA
synthetase; AspS [Halobacterium sp. NRC-1]
Length = 436
Score = 370 bits (940), Expect = e-101
Identities = 186/439 (42%), Positives = 286/439 (64%), Gaps = 4/439 (0%)
Query: 1 MLRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF 60
ML Y ++T + +G+ +AG V E++DLGGI F+ +RD G +QV A + P ++F
Sbjct: 1 MLERTYIEDVTPDDDGEDTTIAGHVHELRDLGGILFVIVRDATGRLQVVAKEDDTP-DLF 59
Query: 61 KLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTR 120
+ L+SEDV+ V G + + +A G E+ P +L V+S+A ++ + V A+L TR
Sbjct: 60 ETAEGLSSEDVVQVTGTLEASDQAPGGVELAPTELTVVSEATDVPSIEISKDVDADLSTR 119
Query: 121 LDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKY 180
LD R +D+R P ++F +RS A ++FY F E+ TP++ EGG +LFP+ Y
Sbjct: 120 LDERHLDVRKPSTKAVFSLRSKAMGAMTDWFYDNRFEEVDTPELSTAGAEGGADLFPVVY 179
Query: 181 FENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESE 240
++ +A+L+QSPQLYKQ+++++G+D++FE+G FRAE+ T+RH++E D E+ ++E
Sbjct: 180 YDKEAYLSQSPQLYKQILVASGVDRLFEVGHAFRAEDFGTSRHVSEIAMFDVELGYVEDH 239
Query: 241 EEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIP 300
+VMD+ E + + I +V E+ ++EL L +L+ P+ FPRIT++EA EIL+D +P
Sbjct: 240 HDVMDVQEESLRHTIRHVVEHAQRELDELGSDLSVPEADFPRITFEEAREILADEYDHVP 299
Query: 301 WGE-DIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRG 359
+ D+DT+GE+LLG+Y E +G F+ YP E K +Y + + FDL YRG
Sbjct: 300 EDDNDLDTKGERLLGEY-FEEQGHPAVFVVGYPDE-KFYYRQDVDGDDVASRKFDLLYRG 357
Query: 360 VEISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLD 419
E+SSGGQREH + L ++RE+G+ PE+FEFYL AF YG+PPHGG+GLG +RLI ++
Sbjct: 358 QELSSGGQREHDIERLTAKMREQGVEPENFEFYLDAFRYGVPPHGGYGLGIDRLIQQLAG 417
Query: 420 IGNIREVILFPRDRRRLVP 438
+ NI+E ILFPRD RL P
Sbjct: 418 LDNIKEAILFPRDPDRLEP 436
>gb|AAF61689.1| (AF219996) aspartyl-tRNA synthetase 2 [Thermus thermophilus]
Length = 422
Score = 326 bits (828), Expect = 2e-88
Identities = 173/425 (40%), Positives = 267/425 (62%), Gaps = 17/425 (4%)
Query: 16 GKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVE 75
G++V++ G++ +DLG I+F+ +RDR G+VQV K+P +P E + V
Sbjct: 13 GQEVELLGFLHWRRDLGRIQFLLLRDRSGVVQVVTGGLKLP------LP----ESALRVR 62
Query: 76 GIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLD-PTGKVKAELDTRLDNRFMDLRNPRVM 134
G+V KA G E+ +++EV+S A P P++ P + +A DT L+ R++ LR +
Sbjct: 63 GLVVENAKAPGGLEVQAKEVEVLSPALEPTPVEIPKEEWRANPDTLLEYRYVTLRGEKAR 122
Query: 135 SIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFLAQSPQLY 194
+ K+++++ R R + ++ F EI TPK++ EGG+ LF + YFE A+LAQSPQLY
Sbjct: 123 APLKVQAALVRGFRRYLDRQDFTEIFTPKVVRAGAEGGSGLFGVDYFEKRAYLAQSPQLY 182
Query: 195 KQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYV 254
KQ+M+ ++V+E+ P++R EEH+T+RHLNE S+D EM FI EE++M L E L+ +
Sbjct: 183 KQIMVGV-FERVYEVAPVWRMEEHHTSRHLNEYLSLDVEMGFIADEEDLMRLEEALLAEM 241
Query: 255 INYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSD-LGKEIPWGEDIDTEGEKLL 313
+ E+++L + PR+T+ EA IL + LG P G+D+ E E+LL
Sbjct: 242 LEEALNTAGDEIRLLGATWPSFPQDIPRLTHAEAKRILKEELG--YPVGQDLSEEAERLL 299
Query: 314 GKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSGGQREHRHD 373
G+Y E G++ F+ RYP +PFY Y ++ ++FDL +RG+EI+SGGQR HR++
Sbjct: 300 GEYAKERWGSDWLFVTRYPRSVRPFYT--YPEEDGTTRSFDLLFRGLEITSGGQRIHRYE 357
Query: 374 ILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDR 433
L+E ++ KG++PE+F YL F+YGMPPHGGF +GAERL ++L + N+R FPRDR
Sbjct: 358 ELLESLKAKGMDPEAFHGYLEVFKYGMPPHGGFAIGAERLTQKLLGLPNVRYARAFPRDR 417
Query: 434 RRLVP 438
RL P
Sbjct: 418 HRLTP 422
>pir||H75443 aspartyl-tRNA synthetase, non-discriminating - Deinococcus
radiodurans (strain R1)
>gi|6458780|gb|AAF10623.1|AE001956_4 (AE001956)
aspartyl-tRNA synthetase, non-discriminating
[Deinococcus radiodurans]
Length = 435
Score = 318 bits (806), Expect = 9e-86
Identities = 177/438 (40%), Positives = 257/438 (58%), Gaps = 20/438 (4%)
Query: 10 ITEEL---NGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKL 66
+T EL G+ VK+ G+V +DLGG++F+ +RD G+ Q +P
Sbjct: 9 LTRELPQHEGQTVKLQGFVHARRDLGGVQFLVLRDVTGVTQCVGSGLTLPL--------- 59
Query: 67 NSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLD-PTGKVKAELDTRLDNRF 125
+E + V G V PKA GFE+ E VIS A P++ P + +T LD R
Sbjct: 60 -AESSVEVVGKVKAHPKAPGGFEVQVEDFRVISAATEATPVEIPKMEWNVNPETMLDYRV 118
Query: 126 MDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDA 185
+ +R + + K+++ + A R EGF EI TPKI++ EGG LFP+ YF + A
Sbjct: 119 VTVRGLKERAALKVQAELVDAFRAHLRGEGFTEISTPKIVSAGAEGGANLFPIDYFGHPA 178
Query: 186 FLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMD 245
+LAQSPQLYKQ+M+ ++VFE+ ++RAEEH T+RHLNE S+D EM FIE EE+VM
Sbjct: 179 YLAQSPQLYKQIMVGV-FERVFEVAAVYRAEEHATSRHLNEYLSLDVEMGFIEDEEDVMG 237
Query: 246 LLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIPWGEDI 305
L RL+ ++ +R ++ E ++L + + PRIT +A +++++ G+D+
Sbjct: 238 LENRLLASIMERLRATSQAEFELLGATIPDVPAHIPRITLMDARQLVTEKYGHPVGGKDL 297
Query: 306 DTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMK--YED---KPEVCKAFDLEYRGV 360
D E E+LL ++ E EG++ F+ +YP A+PFY ED EV + FDL +RG+
Sbjct: 298 DPEAERLLSQHFAETEGSDFVFVTKYPRAARPFYAHPELNEDGSVNGEVTRGFDLLFRGI 357
Query: 361 EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDI 420
EI+SGGQR H + +L++ I L PES E Y F+YGMPPHGGF +GAERL ++L I
Sbjct: 358 EITSGGQRIHDYGMLMDSIAAYKLKPESLEGYTEVFKYGMPPHGGFAIGAERLTAKLLGI 417
Query: 421 GNIREVILFPRDRRRLVP 438
N+R FPRDR RL P
Sbjct: 418 ANVRYARAFPRDRHRLTP 435
>pir||D75212 asparagine--tRNA ligase (EC 6.1.1.22) PAB2203 - Pyrococcus abyssi
(strain Orsay) >gi|5457656|emb|CAB49147.1| (AJ248283)
ASPARAGINYL-TRNA SYNTHETASE (EC 6.1.1.22)
(ASPARAGINE--TRNA LIGASE) (ASNRS) [Pyrococcus abyssi]
Length = 434
Score = 305 bits (772), Expect = 8e-82
Identities = 170/445 (38%), Positives = 266/445 (59%), Gaps = 18/445 (4%)
Query: 1 MLRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF 60
M+ Y +I EL+GK+VK+AGWV +G F+WIRD GI+Q K V +++F
Sbjct: 1 MIEKTYCQDIKPELDGKRVKLAGWVYSNMRVGKKIFLWIRDSTGIIQTVIAKNVVGEDVF 60
Query: 61 KLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVI-SKAKTPLPLDPTGKVKAELDT 119
+ KL E ++VEGIV +A G E+ EKL+VI + ++ P+P +P +A +
Sbjct: 61 ETAKKLGRESSVIVEGIVKADERAPGGAEVHVEKLKVIQAVSEFPIPENPE---QASPEL 117
Query: 120 RLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLK 179
LD R + +R+P+V +I +++ ++ A RE+ +EG+ E+ P ++ A EGG LF LK
Sbjct: 118 LLDYRHLHIRSPKVSAIMRVKETLIMAAREWLLREGWHEVFPPILVTGAVEGGATLFKLK 177
Query: 180 YFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIES 239
YF+ A+L+QS QLY + + GL+KV+ + P FRAE+ T RHL E W ++ E A+++
Sbjct: 178 YFDKVAYLSQSAQLYLEAAI-FGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDL 236
Query: 240 EEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKK---PFPRITYDEALEILSDLG 296
++M + E L+ Y++ E +KE+++ +L K PFPRI+YDEA+EIL G
Sbjct: 237 -WDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIEILQSKG 295
Query: 297 KEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDL- 355
+I WG+D+ + E+ +L E +F+Y YP K FY+ + + P A D+
Sbjct: 296 VKIEWGDDMGADEER-----VLTQEFDRPFFVYGYPKHIKAFYMKEDPNDPRKVLAADML 350
Query: 356 --EYRGVEISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERL 413
E G EI G +RE +D LV++I+E+G++P+ +E+YL +YG PH GFGLG ERL
Sbjct: 351 APEGYG-EIIGGSEREDNYDKLVQRIKEEGMDPKDYEWYLDLRKYGSVPHSGFGLGVERL 409
Query: 414 IMRMLDIGNIREVILFPRDRRRLVP 438
+ +L + +IR LFPR R+ P
Sbjct: 410 VAWVLKLDHIRWATLFPRTPARIYP 434
>pir||B71248 asparagine--tRNA ligase (EC 6.1.1.22) - Pyrococcus horikoshii
>gi|3256630|dbj|BAA29313.1| (AP000001) 434aa long
hypothetical asparaginyl-tRNA synthetase [Pyrococcus
horikoshii]
Length = 434
Score = 301 bits (763), Expect = 9e-81
Identities = 172/445 (38%), Positives = 259/445 (57%), Gaps = 18/445 (4%)
Query: 1 MLRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF 60
M+ Y E+ EL+GKKV++AGWV +G F+WIRD GIVQ K V +E F
Sbjct: 1 MIEKVYCQEVKPELDGKKVRLAGWVYTNMRVGKKIFLWIRDSTGIVQAVVAKNVVGEETF 60
Query: 61 KLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVI-SKAKTPLPLDPTGKVKAELDT 119
+ KL E ++VEGIV +A G E+ EKLEVI + ++ P+P +P +A +
Sbjct: 61 EKAKKLGRESSVIVEGIVKADERAPGGAEVHVEKLEVIQAVSEFPIPENPE---QASPEL 117
Query: 120 RLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLK 179
LD R + +R P+ +I K++ ++ A RE+ K+G+ E+ P ++ A EGG LF LK
Sbjct: 118 LLDYRHLHIRTPKASAIMKVKETLIMAAREWLLKDGWHEVFPPILVTGAVEGGATLFKLK 177
Query: 180 YFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIES 239
YF+ A+L+QS QLY + + GL+KV+ + P FRAE+ T RHL E W ++ E A+++
Sbjct: 178 YFDKYAYLSQSAQLYLEAAI-FGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDL 236
Query: 240 EEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKK---PFPRITYDEALEILSDLG 296
++M + E L+ Y++ E +KE+++ +L K PFPRI+YDEA++IL G
Sbjct: 237 -WDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAIDILQSKG 295
Query: 297 KEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDL- 355
+ WG+D+ + E+ +L E +F+Y YP K FY+ + + P A D+
Sbjct: 296 VNVEWGDDLGADEER-----VLTEEFDRPFFVYGYPKHIKAFYMKEDPNDPRKVLASDML 350
Query: 356 --EYRGVEISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERL 413
E G EI G QRE +D L+ +I E+G++P+ +E+YL YG PH GFGLG ERL
Sbjct: 351 APEGYG-EIIGGSQREDDYDKLLNRILEEGMDPKDYEWYLDLRRYGSVPHSGFGLGVERL 409
Query: 414 IMRMLDIGNIREVILFPRDRRRLVP 438
+ +L + +IR LFPR RL P
Sbjct: 410 VAWVLKLDHIRWAALFPRTPARLYP 434
>pir||T04810 aspartate--tRNA ligase homolog F10M23.210 - Arabidopsis thaliana
>gi|4455210|emb|CAB36533.1| (AL035440) putative
aspartate-tRNA ligase [Arabidopsis thaliana]
>gi|7269540|emb|CAB79542.1| (AL161566) putative
aspartate-tRNA ligase [Arabidopsis thaliana]
Length = 504
Score = 292 bits (740), Expect = 5e-78
Identities = 166/442 (37%), Positives = 253/442 (56%), Gaps = 25/442 (5%)
Query: 8 SEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLN 67
S + EE+ G +V + G + + + +G F+ +R+ VQ + +V + K + +L+
Sbjct: 77 SNLVEEIVGSEVSIRGRLHKNRLVGTKLFVILRESGFTVQCVVEETRVGANMIKFVKQLS 136
Query: 68 SEDVIVVEGIVNFTPKAKLG----FEIIPEKLEVISKAKTPLPLDPTGKVKAELD----- 118
E V+ + G+V+ K G EI K+ +S++ LPL ++E D
Sbjct: 137 RESVVELIGVVSHPKKPLTGTTQQVEIHVRKMYCLSRSLPNLPLVVEDAARSESDIEKSG 196
Query: 119 --TRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELF 176
TRL+NR +D+R P +IF+I+ V A RE+ +GF+EIHTPK+IA ++EGG+ +F
Sbjct: 197 KDTRLNNRVLDIRTPANQAIFRIQCQVQIAFREYLQSKGFLEIHTPKLIAGSSEGGSAVF 256
Query: 177 PLKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAF 236
L Y A LAQSPQL+KQM + + +VFE+GP+FRAE+ T RHL E +D EM
Sbjct: 257 RLDYKGQPACLAQSPQLHKQMAICGDMRRVFEVGPVFRAEDSFTHRHLCEFVGLDVEMEI 316
Query: 237 IESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLG 296
E+MDL+ L ++ + E KEL+ + +K +P + EA E + LG
Sbjct: 317 RMHYSEIMDLVGELFPFIFTKIEERCPKELESV-------RKQYPFQSLKEAGEEVDPLG 369
Query: 297 KEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLE 356
D++TE E+ LG+ +LE E Y ++RYPS +PFY M YE+ +FD+
Sbjct: 370 -------DLNTESERKLGQLVLEKYKTEFYMLHRYPSAVRPFYTMPYENDSNYSNSFDVF 422
Query: 357 YRGVEISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMR 416
RG EI SG QR H ++L ++ RE G++ ++ Y+ AF YG PPHGGFG+G ER++M
Sbjct: 423 IRGEEIMSGAQRIHDPELLEKRARECGIDVKTISTYIDAFRYGAPPHGGFGVGLERVVML 482
Query: 417 MLDIGNIREVILFPRDRRRLVP 438
+ + NIR+ LFPRD +RL P
Sbjct: 483 LCALNNIRKTSLFPRDSQRLTP 504
>emb|CAC11659.1| (AL445064) probable asparaginyl--tRNA synthetase [Thermoplasma
acidophilum]
Length = 429
Score = 281 bits (711), Expect = 1e-74
Identities = 158/433 (36%), Positives = 250/433 (57%), Gaps = 17/433 (3%)
Query: 11 TEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSED 70
T+ G KV + GWV ++ GG+ F+ +RD GI+Q TA K ++P++++ I L E
Sbjct: 9 TKAYVGSKVSIRGWVYRIRSSGGVTFVVVRDSSGIIQCTARKNELPEDVYDTISSLGIES 68
Query: 71 VIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRN 130
+ G + ++ G+EI + V K + P K + E + LDNR + LR+
Sbjct: 69 SVEFHGTLKEDRRSPSGYEIAVDSFRVYQKND----VFPITKDQGE-EFLLDNRHLWLRS 123
Query: 131 PRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFLAQS 190
S+ KIRS++FR+ +FFY+ G+ ++ TP +++TA EGG+ LF + +F +L QS
Sbjct: 124 REFTSVLKIRSTIFRSFADFFYENGYYQVQTPFMVSTAVEGGSTLFKVDFFGEPIYLNQS 183
Query: 191 PQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERL 250
Q Y + M+ + L+KVF I P FRAE+ T RHL E W +AE+A+I++ E+MD+ ER+
Sbjct: 184 AQFYLETMIYS-LEKVFTIAPSFRAEKSRTRRHLTEYWHAEAEVAWIDN-NEMMDIEERM 241
Query: 251 ILYVINYVRENNEKELKILEFE---LNEPKKPFPRITYDEALEILSDLGKEIPWGEDIDT 307
I Y+++ V E+NE ELK+L + L K PFPRI Y E +++ + +G + +G+D+
Sbjct: 242 IYYIVSRVTEDNEDELKMLNRDPEVLKAMKPPFPRIRYSEIIKVANSIGLPLKYGDDLGA 301
Query: 308 EGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKP-EVCKAFDLEYRGV-EISSG 365
+ E+ + + F+ YP + KPFY+ + P EV L G EI G
Sbjct: 302 DEER-----QITMKYDRPIFVTNYPKDLKPFYMPVDPENPGEVLNHDMLAPEGYGEIIGG 356
Query: 366 GQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIRE 425
QR +D L+++IRE L+ ++ +Y+ +YG PH GFGLG +RL M ++ + NIRE
Sbjct: 357 SQRIWNYDELMQRIREANLDESAYYWYVDLRKYGSVPHSGFGLGLDRLAMWIMHLDNIRE 416
Query: 426 VILFPRDRRRLVP 438
I +PR RR P
Sbjct: 417 AIPYPRTIRRTKP 429
>gi|4557513 aspartyl-tRNA synthetase [Homo sapiens]
>gi|135098|sp|P14868|SYD_HUMAN ASPARTYL-TRNA SYNTHETASE
(ASPARTATE--TRNA LIGASE) (ASPRS) >gi|68530|pir||SYHUDT
aspartate--tRNA ligase (EC 6.1.1.12) [similarity] -
human >gi|179102|gb|AAA35567.1| (J05032) aspartyl-tRNA
synthetase [Homo sapiens]
Length = 500
Score = 276 bits (699), Expect = 3e-73
Identities = 158/426 (37%), Positives = 240/426 (56%), Gaps = 24/426 (5%)
Query: 36 FIWIRDREGIVQ-VTAPKKKVPQEIFKLIPKLNSEDVIVVEGIVNFTPKAKLG------F 88
F+ +R ++ VQ + A +++ K +N E ++ VEG+V + K+G
Sbjct: 76 FLVLRQQQFNVQALVAVGDHASKQMVKFAANINKESIVDVEGVVRKVNQ-KIGSCTQQDV 134
Query: 89 EIIPEKLEVISKAKTPLPL------------DPTGKVKAELDTRLDNRFMDLRNPRVMSI 136
E+ +K+ VIS A+ LPL + G+ DTRLDNR +DLR ++
Sbjct: 135 ELHVQKIYVISLAEPRLPLQLDDAVRPEQEGEEEGRATVNQDTRLDNRVIDLRTSTSQAV 194
Query: 137 FKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFLAQSPQLYKQ 196
F+++S + RE +GF+EI TPKII+ A+EGG +F + YF+N+A+LAQSPQLYKQ
Sbjct: 195 FRLQSGICHLFRETLINKGFVEIQTPKIISAASEGGANVFTVSYFKNNAYLAQSPQLYKQ 254
Query: 197 MMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYVIN 256
M + +KVF IGP+FRAE+ NT RHL E +D EMAF EVM+ + ++ +
Sbjct: 255 MCICADFEKVFSIGPVFRAEDSNTHRHLTEFVGLDIEMAFNYHYHEVMEEIADTMVQIFK 314
Query: 257 YVRENNEKELKILEFELN-EPKK---PFPRITYDEALEILSDLGKEIPWGEDIDTEGEKL 312
++E + E++ + + EP K P R+ Y EAL +L + G E+ +D+ T EKL
Sbjct: 315 GLQERFQTEIQTVNKQFPCEPFKFLEPTLRLEYCEALAMLREAGVEMGDEDDLSTPNEKL 374
Query: 313 LGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSGGQREHRH 372
LG + E + Y + +YP +PFY M P+ K++D+ RG EI SG QR H
Sbjct: 375 LGHLVKEKYDTDFYILDKYPLAVRPFYTMPDPRNPKQSKSYDMFMRGEEILSGAQRIHDP 434
Query: 373 DILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRD 432
+L E+ G + E + Y+ +F +G PPH G G+G ER+ M L + N+R+ +FPRD
Sbjct: 435 QLLTERALHHGNDLEKIKAYIDSFRFGAPPHAGGGIGLERVTMLFLGLHNVRQTSMFPRD 494
Query: 433 RRRLVP 438
+RL P
Sbjct: 495 PKRLTP 500
>gi|6323011 Aspartyl-tRNA synthetase, cytosolic; Dps1p [Saccharomyces
cerevisiae] >gi|135100|sp|P04802|SYDC_YEAST
ASPARTYL-TRNA SYNTHETASE, CYTOPLASMIC (ASPARTATE--TRNA
LIGASE) (ASPRS) >gi|68532|pir||SYBYDC aspartate--tRNA
ligase (EC 6.1.1.12), cytosolic [validated] - yeast
(Saccharomyces cerevisiae) >gi|3370|emb|CAA27269.1|
(X03606) AspRS (aa 1-557) [Saccharomyces cerevisiae]
>gi|3411|emb|CAA29865.1| (X06665) aspartyl tRNA synthase
[Saccharomyces cerevisiae] >gi|1297012|emb|CAA66172.1|
(X97560) aspartyl-tRNA synthetase [Saccharomyces
cerevisiae] >gi|1360191|emb|CAA97464.1| (Z73123) ORF
YLL018c [Saccharomyces cerevisiae]
Length = 557
Score = 275 bits (696), Expect = 7e-73
Identities = 165/451 (36%), Positives = 244/451 (53%), Gaps = 29/451 (6%)
Query: 17 KKVKVAGWVQEVKDLGG-IKFIWIRDREGIVQVTAPKKK---VPQEIFKLIPKLNSEDVI 72
K+V V + G + F+ +R + ++Q K + + + K LN E ++
Sbjct: 107 KEVLFRARVHNTRQQGATLAFLTLRQQASLIQGLVKANKEGTISKNMVKWAGSLNLESIV 166
Query: 73 VVEGIVNFTPK-----AKLGFEIIPEKLEVISKAKTPLP--LDPTGKVKAE--------- 116
+V GIV + EI K+ IS+ LP L+ + +AE
Sbjct: 167 LVRGIVKKVDEPIKSATVQNLEIHITKIYTISETPEALPILLEDASRSEAEAEAAGLPVV 226
Query: 117 -LDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTEL 175
LDTRLD R +DLR +IF+I++ V RE+ + F E+HTPK++ +EGG+ +
Sbjct: 227 NLDTRLDYRVIDLRTVTNQAIFRIQAGVCELFREYLATKKFTEVHTPKLLGAPSEGGSSV 286
Query: 176 FPLKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMA 235
F + YF+ A+LAQSPQ KQ ++ ++V+EIGP+FRAE NT RH+ E +D EMA
Sbjct: 287 FEVTYFKGKAYLAQSPQFNKQQLIVADFERVYEIGPVFRAENSNTHRHMTEFTGLDMEMA 346
Query: 236 FIESEEEVMDLLERLILYVINYV--RENNEKELKILEFELNEPKKP----FPRITYDEAL 289
F E EV+D L L +++ + + R +E EL ++ + E K P R+TY E +
Sbjct: 347 FEEHYHEVLDTLSELFVFIFSELPKRFAHEIELVRKQYPVEEFKLPKDGKMVRLTYKEGI 406
Query: 290 EILSDLGKEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEV 349
E+L GKEI ED+ TE EK LGK + + + Y + ++P E +PFY M P+
Sbjct: 407 EMLRAAGKEIGDFEDLSTENEKFLGKLVRDKYDTDFYILDKFPLEIRPFYTMPDPANPKY 466
Query: 350 CKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPE--SFEFYLRAFEYGMPPHGGFG 407
++D RG EI SG QR H H +L E+++ GL+PE + Y F YG PPH G G
Sbjct: 467 SNSYDFFMRGEEILSGAQRIHDHALLQERMKAHGLSPEDPGLKDYCDGFSYGCPPHAGGG 526
Query: 408 LGAERLIMRMLDIGNIREVILFPRDRRRLVP 438
+G ER++M LD+ NIR LFPRD +RL P
Sbjct: 527 IGLERVVMFYLDLKNIRRASLFPRDPKRLRP 557
>pdb|1ASZ|A Chain A, Aspartyl Trna Synthetase (Asprs) (E.C.6.1.1.12) Complexed
With Transfer Ribonucleic Acid (Trnaasp) And Atp
>gi|1064988|pdb|1ASZ|B Chain B, Aspartyl Trna Synthetase
(Asprs) (E.C.6.1.1.12) Complexed With Transfer
Ribonucleic Acid (Trnaasp) And Atp
>gi|1064982|pdb|1ASY|A Chain A, Aspartyl Trna Synthetase
(Asprs) (E.C.6.1.1.12) Complexed With Transfer
Ribonucleic Acid (Trnaasp) >gi|1064984|pdb|1ASY|B Chain
B, Aspartyl Trna Synthetase (Asprs) (E.C.6.1.1.12)
Complexed With Transfer Ribonucleic Acid (Trnaasp)
Length = 490
Score = 275 bits (696), Expect = 7e-73
Identities = 165/451 (36%), Positives = 244/451 (53%), Gaps = 29/451 (6%)
Query: 17 KKVKVAGWVQEVKDLGG-IKFIWIRDREGIVQVTAPKKK---VPQEIFKLIPKLNSEDVI 72
K+V V + G + F+ +R + ++Q K + + + K LN E ++
Sbjct: 40 KEVLFRARVHNTRQQGATLAFLTLRQQASLIQGLVKANKEGTISKNMVKWAGSLNLESIV 99
Query: 73 VVEGIVNFTPK-----AKLGFEIIPEKLEVISKAKTPLP--LDPTGKVKAE--------- 116
+V GIV + EI K+ IS+ LP L+ + +AE
Sbjct: 100 LVRGIVKKVDEPIKSATVQNLEIHITKIYTISETPEALPILLEDASRSEAEAEAAGLPVV 159
Query: 117 -LDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTEL 175
LDTRLD R +DLR +IF+I++ V RE+ + F E+HTPK++ +EGG+ +
Sbjct: 160 NLDTRLDYRVIDLRTVTNQAIFRIQAGVCELFREYLATKKFTEVHTPKLLGAPSEGGSSV 219
Query: 176 FPLKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMA 235
F + YF+ A+LAQSPQ KQ ++ ++V+EIGP+FRAE NT RH+ E +D EMA
Sbjct: 220 FEVTYFKGKAYLAQSPQFNKQQLIVADFERVYEIGPVFRAENSNTHRHMTEFTGLDMEMA 279
Query: 236 FIESEEEVMDLLERLILYVINYV--RENNEKELKILEFELNEPKKP----FPRITYDEAL 289
F E EV+D L L +++ + + R +E EL ++ + E K P R+TY E +
Sbjct: 280 FEEHYHEVLDTLSELFVFIFSELPKRFAHEIELVRKQYPVEEFKLPKDGKMVRLTYKEGI 339
Query: 290 EILSDLGKEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEV 349
E+L GKEI ED+ TE EK LGK + + + Y + ++P E +PFY M P+
Sbjct: 340 EMLRAAGKEIGDFEDLSTENEKFLGKLVRDKYDTDFYILDKFPLEIRPFYTMPDPANPKY 399
Query: 350 CKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPE--SFEFYLRAFEYGMPPHGGFG 407
++D RG EI SG QR H H +L E+++ GL+PE + Y F YG PPH G G
Sbjct: 400 SNSYDFFMRGEEILSGAQRIHDHALLQERMKAHGLSPEDPGLKDYCDGFSYGCPPHAGGG 459
Query: 408 LGAERLIMRMLDIGNIREVILFPRDRRRLVP 438
+G ER++M LD+ NIR LFPRD +RL P
Sbjct: 460 IGLERVVMFYLDLKNIRRASLFPRDPKRLRP 490
>pdb|1EOV|A Chain A, Free Aspartyl-Trna Synthetase (Asprs) (E.C. 6.1.1.12) From
Yeast
Length = 487
Score = 275 bits (696), Expect = 7e-73
Identities = 165/451 (36%), Positives = 244/451 (53%), Gaps = 29/451 (6%)
Query: 17 KKVKVAGWVQEVKDLGG-IKFIWIRDREGIVQVTAPKKK---VPQEIFKLIPKLNSEDVI 72
K+V V + G + F+ +R + ++Q K + + + K LN E ++
Sbjct: 37 KEVLFRARVHNTRQQGATLAFLTLRQQASLIQGLVKANKEGTISKNMVKWAGSLNLESIV 96
Query: 73 VVEGIVNFTPK-----AKLGFEIIPEKLEVISKAKTPLP--LDPTGKVKAE--------- 116
+V GIV + EI K+ IS+ LP L+ + +AE
Sbjct: 97 LVRGIVKKVDEPIKSATVQNLEIHITKIYTISETPEALPILLEDASRSEAEAEAAGLPVV 156
Query: 117 -LDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTEL 175
LDTRLD R +DLR +IF+I++ V RE+ + F E+HTPK++ +EGG+ +
Sbjct: 157 NLDTRLDYRVIDLRTVTNQAIFRIQAGVCELFREYLATKKFTEVHTPKLLGAPSEGGSSV 216
Query: 176 FPLKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMA 235
F + YF+ A+LAQSPQ KQ ++ ++V+EIGP+FRAE NT RH+ E +D EMA
Sbjct: 217 FEVTYFKGKAYLAQSPQFNKQQLIVADFERVYEIGPVFRAENSNTHRHMTEFTGLDMEMA 276
Query: 236 FIESEEEVMDLLERLILYVINYV--RENNEKELKILEFELNEPKKP----FPRITYDEAL 289
F E EV+D L L +++ + + R +E EL ++ + E K P R+TY E +
Sbjct: 277 FEEHYHEVLDTLSELFVFIFSELPKRFAHEIELVRKQYPVEEFKLPKDGKMVRLTYKEGI 336
Query: 290 EILSDLGKEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEV 349
E+L GKEI ED+ TE EK LGK + + + Y + ++P E +PFY M P+
Sbjct: 337 EMLRAAGKEIGDFEDLSTENEKFLGKLVRDKYDTDFYILDKFPLEIRPFYTMPDPANPKY 396
Query: 350 CKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPE--SFEFYLRAFEYGMPPHGGFG 407
++D RG EI SG QR H H +L E+++ GL+PE + Y F YG PPH G G
Sbjct: 397 SNSYDFFMRGEEILSGAQRIHDHALLQERMKAHGLSPEDPGLKDYCDGFSYGCPPHAGGG 456
Query: 408 LGAERLIMRMLDIGNIREVILFPRDRRRLVP 438
+G ER++M LD+ NIR LFPRD +RL P
Sbjct: 457 IGLERVVMFYLDLKNIRRASLFPRDPKRLRP 487
>gi|11429379 aspartyl-tRNA synthetase [Homo sapiens]
Length = 484
Score = 275 bits (696), Expect = 7e-73
Identities = 157/426 (36%), Positives = 239/426 (55%), Gaps = 24/426 (5%)
Query: 36 FIWIRDREGIVQ-VTAPKKKVPQEIFKLIPKLNSEDVIVVEGIVNFTPKAKLG------F 88
F+ +R ++ VQ + A +++ K +N E ++ VEG+V + K+G
Sbjct: 60 FLVLRQQQFNVQALVAVGDHASKQMVKFAANINKESIVDVEGVVRKVNQ-KIGSCTQQDV 118
Query: 89 EIIPEKLEVISKAKTPLPL------------DPTGKVKAELDTRLDNRFMDLRNPRVMSI 136
E+ +K+ VIS A+ LPL + G+ DTRLDNR +DLR ++
Sbjct: 119 ELHVQKIYVISLAEPRLPLQLDDAVRPEAEGEEEGRATVNQDTRLDNRVIDLRTSTSQAV 178
Query: 137 FKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFLAQSPQLYKQ 196
F+++S + RE +GF+EI TPKII+ A+EGG +F + YF+N+A+LAQSPQLYKQ
Sbjct: 179 FRLQSGICHLFRETLINKGFVEIQTPKIISAASEGGANVFTVSYFKNNAYLAQSPQLYKQ 238
Query: 197 MMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYVIN 256
M + +KVF IGP+FRAE+ NT RHL E +D EMAF EVM+ + ++ +
Sbjct: 239 MCICADFEKVFSIGPVFRAEDSNTHRHLTEFVGLDIEMAFNYHYHEVMEEIADTMVQIFK 298
Query: 257 YVRENNEKELKILEFELN-EPKK---PFPRITYDEALEILSDLGKEIPWGEDIDTEGEKL 312
++E + E++ + + EP K P R+ Y EAL +L + G E+ +D+ T EKL
Sbjct: 299 GLQERFQTEIQTVNKQFPCEPFKFLEPTLRLEYCEALAMLREAGVEMGDEDDLSTPNEKL 358
Query: 313 LGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSGGQREHRH 372
LG + E + Y + +YP +PFY M P+ ++D+ RG EI SG QR H
Sbjct: 359 LGHLVKEKYDTDFYILDKYPLAVRPFYTMPDPRNPKQSNSYDMFMRGEEILSGAQRIHDP 418
Query: 373 DILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRD 432
+L E+ G + E + Y+ +F +G PPH G G+G ER+ M L + N+R+ +FPRD
Sbjct: 419 QLLTERALHHGTDLEKIKAYIDSFRFGAPPHAGGGIGLERVTMLFLGLHNVRQTSMFPRD 478
Query: 433 RRRLVP 438
+RL P
Sbjct: 479 PKRLTP 484
>sp|P15178|SYD_RAT ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|68531|pir||SYRTDT aspartate--tRNA ligase (EC
6.1.1.12) - rat >gi|203066|gb|AAA40789.1| (J04487)
aspartyl-tRNA synthetase [Rattus norvegicus]
>gi|1773257|gb|AAC52981.1| (U30812) aspartyl-tRNA
synthetase [Rattus norvegicus]
Length = 501
Score = 275 bits (695), Expect = 9e-73
Identities = 164/453 (36%), Positives = 250/453 (54%), Gaps = 24/453 (5%)
Query: 9 EITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQ-VTAPKKKVPQEIFKLIPKLN 67
++T + + V V V + G F+ +R ++ VQ + A +++ K +N
Sbjct: 50 DLTVQKADEVVWVRARVHTSRAKGKQCFLVLRQQQFNVQALVAVGDHASKQMVKFAANIN 109
Query: 68 SEDVIVVEGIVNFTPKAKLG------FEIIPEKLEVISKAKTPLPL------------DP 109
E +I VEGIV + K+G E+ +K+ VIS A+ LPL +
Sbjct: 110 KESIIDVEGIVRKVNQ-KIGSCTQQDVELHVQKIYVISLAEPRLPLQLDDAIRPEVEGEE 168
Query: 110 TGKVKAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATAT 169
G+ DTRLDNR +DLR +IF ++S + RE +GF+EI TPKII+ A+
Sbjct: 169 DGRATVNQDTRLDNRIIDLRTSTSQAIFHLQSGICHLFRETLINKGFVEIQTPKIISAAS 228
Query: 170 EGGTELFPLKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWS 229
EGG +F + YF+++A+LAQSPQLYKQM + +KVF IGP+FRAE+ NT RHL E
Sbjct: 229 EGGANVFTVSYFKSNAYLAQSPQLYKQMCICADFEKVFCIGPVFRAEDSNTHRHLTEFVG 288
Query: 230 IDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELN-EPKK---PFPRITY 285
+D EMAF EV++ + ++ + ++E + E++ + + EP K P R+ Y
Sbjct: 289 LDIEMAFNYHYHEVVEEIADTLVQIFKGLQERFQTEIQTVNKQFPCEPFKFLEPTLRLEY 348
Query: 286 DEALEILSDLGKEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYED 345
EAL +L + G E+ ED+ T EKLLG+ + E + Y + +YP +PFY M
Sbjct: 349 CEALAMLREAGVEMDDEEDLSTPNEKLLGRLVKEKYDTDFYVLDKYPLAVRPFYTMPDPR 408
Query: 346 KPEVCKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGG 405
P+ ++D+ RG EI SG QR H +L E+ G++ E + Y+ +F +G PPH G
Sbjct: 409 NPKQSNSYDMFMRGEEILSGAQRIHDPQLLTERALHHGIDLEKIKAYIDSFRFGAPPHAG 468
Query: 406 FGLGAERLIMRMLDIGNIREVILFPRDRRRLVP 438
G+G ER+ M L + N+R+ +FPRD +RL P
Sbjct: 469 GGIGLERVTMLFLGLHNVRQTSMFPRDPKRLTP 501
>sp|P39772|SYN_BACSU ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRNA LIGASE) (ASNRS)
>gi|7437578|pir||B69591 asparagine--tRNA ligase (EC
6.1.1.22) asnS - Bacillus subtilis
>gi|1146247|gb|AAB38455.1| (L47709) asparaginyl-tRNA
synthetase [Bacillus subtilis]
>gi|2634654|emb|CAB14152.1| (Z99115) asparaginyl-tRNA
synthetase [Bacillus subtilis]
Length = 430
Score = 275 bits (695), Expect = 9e-73
Identities = 161/430 (37%), Positives = 243/430 (56%), Gaps = 19/430 (4%)
Query: 16 GKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVE 75
G++V + WV + G I F+ +RD G +Q K +V + IF+ + E + ++
Sbjct: 13 GEEVTIGAWVANKRSSGKIAFLQLRDGTGFIQGVVVKAEVEESIFQTAKSVTQETSLYIK 72
Query: 76 GIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPRVMS 135
GIV ++ LG+E+ +EVI +A T P+ P + + +D+R + LR+ R +
Sbjct: 73 GIVKEDERSPLGYELAVTDIEVIHEA-TDYPITPK---EHGTEFLMDHRHLWLRSKRQHA 128
Query: 136 IFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFLAQSPQLYK 195
I KIR+ + RAT EFF EGF+++ P + +A EG TELF KYF+ DA+L+QS QLY
Sbjct: 129 IMKIRNEIIRATYEFFNNEGFVKVDPPILTGSAPEGTTELFATKYFDEDAYLSQSGQLYM 188
Query: 196 QMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYVI 255
+ + L KVF GP FRAE+ T RHL E W I+ EMAF+E EE + + E + +++
Sbjct: 189 E-AAAMALGKVFSFGPTFRAEKSKTKRHLIEFWMIEPEMAFVEFEEN-LQVQENYVSFIV 246
Query: 256 NYVRENNEKELKIL---EFELNEPKKPFPRITYDEALEILSDLG-KEIPWGEDIDTEGEK 311
V +N + EL L +L + K PFPRITYDEA+E L + G +I WG+D E
Sbjct: 247 QSVLKNCKIELNTLGRDTSKLEQIKAPFPRITYDEAIEFLKEKGFDDIEWGDDFGAPHET 306
Query: 312 LLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDL---EYRGVEISSGGQR 368
+ ++ + FI RYP+ KPFY+ D+ +V DL E G EI G +R
Sbjct: 307 AIAEHY-----DKPVFITRYPTSLKPFYMQPASDREDVVLCADLIAPEGYG-EIIGGSER 360
Query: 369 EHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVIL 428
H ++L +++E GL+ +++++Y +YG PH GFGLG ER + + ++RE I
Sbjct: 361 IHDMELLESRLKEHGLDSDAYKWYAELRKYGSVPHSGFGLGLERTVAWISGAPHVRETIP 420
Query: 429 FPRDRRRLVP 438
FPR RL P
Sbjct: 421 FPRLLNRLYP 430
>pir||T40867 aspartate--tRNA ligase (EC 6.1.1.12) [similarity] - fission yeast
(Schizosaccharomyces pombe) >gi|3618213|emb|CAA20876.1|
(AL031579) aspartyl-trna synthetase, cytoplasmic
[Schizosaccharomyces pombe]
Length = 580
Score = 273 bits (692), Expect = 2e-72
Identities = 165/485 (34%), Positives = 260/485 (53%), Gaps = 54/485 (11%)
Query: 8 SEITEELNGKKVKVAGWVQEVKDLGG-IKFIWIRDREGIVQVTAPKKK--VPQEIFKLIP 64
S+I+ + +G+ V + V + G + F +R + +Q A K + +++ K
Sbjct: 96 SDISAKNDGQTVLLRARVYTSRLQGNKMCFFSLRQKYDTIQALAVVNKDTISKQMVKWCG 155
Query: 65 KLNSEDVIVVEGIVNFTPK-----AKLGFEIIPEKLEVISKAKTPLP--LDPTGK----- 112
++ E +++VEGIV +P+ EI + VIS K LP ++ G+
Sbjct: 156 SISLESIVLVEGIVKKSPEIIKSATVQDAEIHISSIYVISPIKKNLPFLVEDAGRSEEQI 215
Query: 113 --------------VKAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIE 158
V+ LDTRLDNR +DLR P +IF I++ + +A REF F E
Sbjct: 216 RESEENAAEGDSKFVRVNLDTRLDNRVLDLRTPTNQAIFDIQAGICQAFREFLLSNSFNE 275
Query: 159 IHTPKIIATATEGGTELFPLKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEH 218
IHTPK+ ++EGG+ +F ++YF+ D FL+QSPQLYKQM+++ ++VFEIGP+FRAE+
Sbjct: 276 IHTPKMSGASSEGGSNVFKIQYFKTDGFLSQSPQLYKQMLIAADRERVFEIGPVFRAEDS 335
Query: 219 NTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKK 278
NT RH+ E +D EMAF E EVM+ +E+L LY+ +RE K++ ++ +
Sbjct: 336 NTYRHMTEFTGLDLEMAFNEHYHEVMEFIEKLFLYIFKTIREKYAKQVAVVRQQYPSEDF 395
Query: 279 PFP-----RITYDEALEILSDLGK-------------------EIPWGEDIDTEGEKLLG 314
P R + +A+++L + G E P +D T E+ LG
Sbjct: 396 ILPDADRIRFHFKDAVKLLKEAGYRKQLVPGQKVPEDEEFHYCEDPEFDDFSTPEERALG 455
Query: 315 KYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSGGQREHRHDI 374
+ + E + Y I +YPS +PFY M + P ++D +G EI SG QR H ++
Sbjct: 456 QIVREKYHTDFYVIDKYPSSVRPFYTMPDPEDPRYSNSYDFFMKGQEIMSGAQRIHDPEL 515
Query: 375 LVEQIREKGLNPE-SFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDR 433
LVE+++ G++P+ + Y+ AF G PPH G G+G ER++M L++ NIR FPRD
Sbjct: 516 LVERMKALGVSPDVGLQQYIDAFAIGCPPHAGGGIGLERVVMFYLNLPNIRLASSFPRDP 575
Query: 434 RRLVP 438
+RL+P
Sbjct: 576 KRLLP 580
>pir||T10672 aspartate--tRNA ligase homolog F6E21.100 - Arabidopsis thaliana
>gi|7270020|emb|CAB79836.1| (AL161578) aspartate--tRNA
ligase-like protein [Arabidopsis thaliana]
Length = 558
Score = 273 bits (690), Expect = 3e-72
Identities = 163/460 (35%), Positives = 254/460 (54%), Gaps = 29/460 (6%)
Query: 8 SEITEELNGKKVKVAGWVQEVKDLGG-IKFIWIRDREGIVQVT---APKKKVPQEIFKLI 63
S++ EE+ +V + G V + + F+ +R+ VQ + K KV + K +
Sbjct: 99 SDLVEEMLESEVLIRGRVHTNRPTSNKLGFVVLRESGSTVQCVVSQSEKTKVGANMVKYL 158
Query: 64 PKLNSEDVIVVEGIVNFTPKAKLG----FEIIPEKLEVISKAKTPLPLD----------- 108
+L+ E + V G+V + G EI K+ I+K+ LPL
Sbjct: 159 KQLSRESFVDVIGVVTLPKEPLTGTTQQVEIQVRKVYCINKSLAKLPLSVEDAARSEADI 218
Query: 109 ------PTGKVKAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTP 162
P+ + DTRL+ R +DLR P +IF+++ V A RE + F+ IHTP
Sbjct: 219 EASLQTPSPAARVNQDTRLNYRVLDLRTPANQAIFQLQYEVEYAFREKLRFKNFVGIHTP 278
Query: 163 KIIATATEGGTELFPLKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTR 222
K++A ++EGG+ +F L+Y A LAQSPQL+KQM + L +VFE+GP+FRAE+ T R
Sbjct: 279 KLMAGSSEGGSAVFRLEYKGQPACLAQSPQLHKQMAICGDLRRVFEVGPVFRAEDSFTHR 338
Query: 223 HLNEAWSIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELN-EPKKPFP 281
HL E +D EM + E+MDL++ L +++ + E +KEL+ + + EP K P
Sbjct: 339 HLCEFVGLDVEMEIRKHYSEIMDLVDELFVFIFTSLNERCKKELQAVGKQYPFEPLKFLP 398
Query: 282 ---RITYDEALEILSDLGKEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPF 338
R+T++E +++L + G E+ D++TE E+ LG+ +LE E Y ++RYP +PF
Sbjct: 399 KTLRLTFEEGVQMLKEAGVEVDPLGDLNTESERKLGQLVLEKYNTEFYILHRYPKAVRPF 458
Query: 339 YIMKYEDKPEVCKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEY 398
Y M D P +FD+ RG EI SG QR H ++L ++ E G++ ++ Y+ +F Y
Sbjct: 459 YTMTCADNPLYSNSFDVFIRGEEIISGAQRVHIPEVLEQRAGECGIDVKTISTYIDSFRY 518
Query: 399 GMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRRRLVP 438
G P HGGFG+G ER++M + NIR+ LFPRD +RL P
Sbjct: 519 GAPLHGGFGVGLERVVMLFCALNNIRKTSLFPRDPQRLSP 558
>gb|AAF58445.1| (AE003820) Aats-asp gene product [Drosophila melanogaster]
Length = 531
Score = 265 bits (671), Expect = 6e-70
Identities = 157/457 (34%), Positives = 245/457 (53%), Gaps = 29/457 (6%)
Query: 8 SEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQ-VTAPKKKVPQEIFKLIPKL 66
SE++ ++ V V G V + G F+ +R + VQ + A + +++ K +
Sbjct: 78 SELSGQVGKGLVWVRGRVHTSRAKGKQCFLILRQQSSTVQCILAVGDVISKQMVKFAGNI 137
Query: 67 NSEDVIVVEGI-VNFTPK----AKLGFEIIPEKLEVISKAKTPLPL------------DP 109
E +I ++ V + K + E+ E++ VIS+AK LPL D
Sbjct: 138 PKESIIDIQAKPVAVSSKIESCTEQSLELSVEQIFVISQAKAQLPLQIEDASRPENADDA 197
Query: 110 TG-KVKAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATA 168
G ++ DTRLDNR +DLR P +IF++ + V R R+ ++GF EIHTPKII+ A
Sbjct: 198 EGLNIRVNQDTRLDNRVLDLRTPANQAIFRLEAGVCRLFRDILTEQGFTEIHTPKIISAA 257
Query: 169 TEGGTELFPLKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAW 228
+EGG +F + YF++ A+LAQSPQLYKQM ++ DKV+ +G +FRAE+ NT RHL E
Sbjct: 258 SEGGANVFTVSYFKDSAYLAQSPQLYKQMAIAADFDKVYTVGAVFRAEDSNTHRHLTEFV 317
Query: 229 SIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKEL-------KILEFELNEPKKPFP 281
+D EMAF EV+ + + +R+ KE+ K+ F+ EP
Sbjct: 318 GLDLEMAFKYHYHEVLHTIGNTFTSIFKGLRDKYAKEIESVGQQYKVDAFKFLEPPL--- 374
Query: 282 RITYDEALEILSDLGKEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIM 341
+ + + + +L + G E ED+ T EKLLG+ + + Y + ++P +PFY M
Sbjct: 375 ILQFADGVAMLREAGVETGDEEDLSTPNEKLLGRLVKAKYDTDFYILDKFPLAIRPFYTM 434
Query: 342 KYEDKPEVCKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMP 401
+ P ++D+ RG EI SG QR H + L+E+ + G++ Y+ +F YG P
Sbjct: 435 PDPNNPVYSNSYDMFMRGEEILSGAQRIHDPEYLIERAKHHGIDTSKIAAYIESFRYGCP 494
Query: 402 PHGGFGLGAERLIMRMLDIGNIREVILFPRDRRRLVP 438
PH G G+G ER++M L + NIR+ +FPRD +RL P
Sbjct: 495 PHAGGGIGMERVVMLYLGLDNIRKTSMFPRDPKRLTP 531
>gb|AAD21582.1| (AF113612) aspartyl tRNA synthetase [Drosophila melanogaster]
Length = 531
Score = 263 bits (665), Expect = 3e-69
Identities = 156/457 (34%), Positives = 244/457 (53%), Gaps = 29/457 (6%)
Query: 8 SEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQ-VTAPKKKVPQEIFKLIPKL 66
SE++ ++ V V G V + G F+ +R + VQ + A + +++ K +
Sbjct: 78 SELSGQVGKGLVWVRGRVHTSRAKGKQCFLILRQQSSTVQCILAVGDVISKQMVKFAGNI 137
Query: 67 NSEDVIVVEGI-VNFTPK----AKLGFEIIPEKLEVISKAKTPLPL------------DP 109
E +I ++ V + K + E+ E++ VIS+AK LPL D
Sbjct: 138 PKESIIDIQAKPVAVSSKIESCTEQSLELSVEQIFVISQAKAQLPLQIEDASRPENADDA 197
Query: 110 TG-KVKAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATA 168
G ++ DTRLDNR +DLR P +IF++ + V R R+ ++GF EIHTPKII+ A
Sbjct: 198 EGLNIRVNQDTRLDNRVLDLRTPANQAIFRLEAGVCRLFRDILTEQGFTEIHTPKIISAA 257
Query: 169 TEGGTELFPLKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAW 228
+EGG +F + YF++ A+LAQSPQLYKQM ++ DKV+ +G +FRAE+ NT RHL E
Sbjct: 258 SEGGANVFTVSYFKDSAYLAQSPQLYKQMAIAADFDKVYTVGAVFRAEDSNTHRHLTEFV 317
Query: 229 SIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKEL-------KILEFELNEPKKPFP 281
+D EMAF EV+ + + +R+ KE+ K+ F+ EP
Sbjct: 318 GLDLEMAFKYHYHEVLHTIGNTFTSIFKGLRDKYAKEIESVGQQYKVDAFKFLEPPL--- 374
Query: 282 RITYDEALEILSDLGKEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIM 341
+ + + + +L + G E ED+ T EKLLG+ + + Y + ++P +PFY M
Sbjct: 375 ILQFADGVAMLREAGVETGDEEDLSTPNEKLLGRLVKAKYDTDFYILDKFPLAIRPFYTM 434
Query: 342 KYEDKPEVCKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMP 401
+ P ++D+ RG EI SG QR H + L+E+ + G++ Y+ +F YG P
Sbjct: 435 PDPNNPVYSNSYDMFMRGEEILSGAQRIHDPEYLIERAKHHGIDTSKIAAYIESFRYGCP 494
Query: 402 PHGGFGLGAERLIMRMLDIGNIREVILFPRDRRRLVP 438
PH G G+G ER++M L + NIR+ + PRD +RL P
Sbjct: 495 PHAGGGIGMERVVMLYLGLDNIRKTSMLPRDPKRLTP 531
>sp|Q03577|SYD_CAEEL PROBABLE ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|280519|pir||S28278 aspartate--tRNA ligase (EC
6.1.1.12) [similarity] - Caenorhabditis elegans
>gi|3873792|emb|CAA79536.1| (Z19152) putative
Aspartyl-tRNA synthetase, contains similarity to Pfam
domain: PF00152 (tRNA synthetases class II (D, K and
N)), Score=579.2, E-value=8.2e-171, N=1; PF01336
(Aspartyl-tRNA synthetase (AspRS), N terminus),
Score=345.6, E-value=1.7e-100,>
Length = 531
Score = 259 bits (654), Expect = 6e-68
Identities = 153/452 (33%), Positives = 240/452 (52%), Gaps = 32/452 (7%)
Query: 17 KKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTA-PKKKVPQEIFKLIPKLNSEDVIVVE 75
K V V G + + G F+ +R VQV +K+ +++ K + ++ E ++ V
Sbjct: 82 KDVWVRGRIHTTRSKGKNCFLVLRQGVYTVQVAMFMNEKISKQMLKFVSSISKESIVDVY 141
Query: 76 GIVNFTPK-----AKLGFEIIPEKLEVISKAKTPLPLD--------PTGKVKAE------ 116
+N + E++ +++ V+S + LPL PT + KA
Sbjct: 142 ATINKVDNPIESCTQKDVELLAQQVFVVSTSAPKLPLQIEDASRRAPTDEEKASEQENQL 201
Query: 117 ----LDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGG 172
LDTRLDNR +DLR P +IF+I++ + R GF+EI PKII+ +EGG
Sbjct: 202 AVVNLDTRLDNRVIDLRTPTSHAIFRIQAGICNQFRNILDVRGFVEIMAPKIISAPSEGG 261
Query: 173 TELFPLKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDA 232
+F + YF+ A+LAQSPQLYKQM ++ +KV+ IGP+FRAE+ NT RH+ E +D
Sbjct: 262 ANVFEVSYFKGSAYLAQSPQLYKQMAIAGDFEKVYTIGPVFRAEDSNTHRHMTEFVGLDL 321
Query: 233 EMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFP------RITYD 286
EMAF EVM+ + ++ + +++N + E+ + + P +PF + Y
Sbjct: 322 EMAFNFHYHEVMETIAEVLTQMFKGLQQNYQDEIAAVGNQY--PAEPFQFCEPPLILKYP 379
Query: 287 EALEILSDLGKEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDK 346
+A+ +L + G EI +D+ T EK LGK + E + Y + ++P +PFY M
Sbjct: 380 DAITLLRENGIEIGDEDDLSTPVEKFLGKLVKEKYSTDFYVLDKFPLSVRPFYTMPDAHD 439
Query: 347 PEVCKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGF 406
++D+ RG EI SG QR H D+LVE+ + ++ + Y+ +F+YG PPH G
Sbjct: 440 ERYSNSYDMFMRGEEILSGAQRIHDADMLVERAKHHQVDLAKIQSYIDSFKYGCPPHAGG 499
Query: 407 GLGAERLIMRMLDIGNIREVILFPRDRRRLVP 438
G+G ER+ M L + NIR LFPRD +RL P
Sbjct: 500 GIGLERVTMLFLGLHNIRLASLFPRDPKRLTP 531
>pir||S71074 asparagine--tRNA ligase (EC 6.1.1.22) asnS2 - Lactobacillus
delbrueckii subsp. bulgaricus
>gi|1495654|emb|CAA61604.1| (X89439) asparagine--tRNA
ligase [Lactobacillus delbrueckii]
Length = 432
Score = 254 bits (641), Expect = 2e-66
Identities = 149/428 (34%), Positives = 237/428 (54%), Gaps = 17/428 (3%)
Query: 17 KKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVEG 76
++V++ W+ + + G I F+ +RD Q K V +E+F+ L E + G
Sbjct: 16 EEVRMHVWLTDKRSSGKIVFLQLRDGTAFFQGVVRKNDVSEEVFEAAKGLRQEASFYLTG 75
Query: 77 IVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPRVMSI 136
++ ++ G+EI LEV+S + P + +D LD+R + LR+ R +I
Sbjct: 76 TIHEDARSHFGYEIQISDLEVVSNNEGY----PITNKEHGIDFLLDHRHLWLRSRRPFAI 131
Query: 137 FKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFLAQSPQLYKQ 196
+IR+ +F+AT +FF EGF++ P ++ +A EG TELF + YF +DA+L+QS QLY +
Sbjct: 132 MQIRNRIFKATVDFFENEGFVKFDAPLLMHSAPEGTTELFHIDYFNHDAYLSQSGQLYGE 191
Query: 197 MMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYVIN 256
+ + K+F GP FRAE T RHL E W ++ EMA++ ++E +DL ER + YV+
Sbjct: 192 -VGAEAFGKIFTFGPTFRAEASKTRRHLTEFWMMEPEMAWMH-QDESLDLQERFLSYVVG 249
Query: 257 YVRENNEKELKILEFELNEPKKP----FPRITYDEALEILSDLGKEIPWGEDIDTEGEKL 312
V E+ E EL IL +L++ + + R++YD+A+++L + GK+ WG+D E
Sbjct: 250 QVLEHCEYELSILGRDLDKLRPAAEGNYTRLSYDDAVKMLQEAGKDFKWGDDFGAPDEAF 309
Query: 313 LGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEY-RGV-EISSGGQREH 370
L + + +FI YP KPFY+ K + P D+E G EI G +RE
Sbjct: 310 LSE-----QFDRPFFIVNYPVAIKPFYMKKNPENPLTYLCADVEAPEGYGEIMGGSEREA 364
Query: 371 RHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFP 430
+D L QI E GLN + + +YL +YG PH GFG+G ER+I + + ++RE + FP
Sbjct: 365 DYDTLKAQIEEAGLNLDDYSWYLDLRKYGSVPHSGFGMGFERVIAWICKLDHVREAVPFP 424
Query: 431 RDRRRLVP 438
R R+ P
Sbjct: 425 RMINRMQP 432
>pir||S71072 asparagine--tRNA ligase (EC 6.1.1.22) asnS1 - Lactobacillus
delbrueckii subsp. bulgaricus
Length = 432
Score = 252 bits (638), Expect = 4e-66
Identities = 148/428 (34%), Positives = 237/428 (54%), Gaps = 17/428 (3%)
Query: 17 KKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVEG 76
++V++ W+ + + G I F+ +RD Q K V +E+F+ L E + G
Sbjct: 16 EEVRMHVWLADKRSSGKIVFLQLRDGTAFFQGVVRKNDVSEEVFEAAKGLRQEASFYLTG 75
Query: 77 IVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPRVMSI 136
++ ++ G+EI LEV+S + P + +D LD+R + LR+ R +I
Sbjct: 76 TIHEDARSHFGYEIQISDLEVVSNNEGY----PITNKEHGIDFLLDHRHLWLRSRRPFAI 131
Query: 137 FKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFLAQSPQLYKQ 196
+IR+ +F+AT +FF EGF++ P ++ +A EG TELF + YF +DA+L+QS QLY +
Sbjct: 132 MQIRNRIFKATVDFFENEGFVKFDAPLLMHSAPEGTTELFHIDYFNHDAYLSQSGQLYGE 191
Query: 197 MMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYVIN 256
+ + K+F GP FRAE T RHL E W ++ EMA++ ++E +DL ER + YV+
Sbjct: 192 -VGAEAFGKIFTFGPTFRAEASKTRRHLTEFWMMEPEMAWMH-QDESLDLQERFLSYVVG 249
Query: 257 YVRENNEKELKILEFELNEPKKP----FPRITYDEALEILSDLGKEIPWGEDIDTEGEKL 312
V E+ E EL IL ++++ + + R++YD+A+++L + GK+ WG+D E
Sbjct: 250 QVLEHCEYELSILGRDVDKLRPAAEGNYTRLSYDDAVKMLQEAGKDFKWGDDFGAPDEAF 309
Query: 313 LGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEY-RGV-EISSGGQREH 370
L + + +FI YP KPFY+ K + P D+E G EI G +RE
Sbjct: 310 LSE-----QFDRPFFIVNYPVAIKPFYMKKNPENPLTYLCADVEAPEGYGEIMGGSEREA 364
Query: 371 RHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFP 430
+D L QI E GLN + + +YL +YG PH GFG+G ER+I + + ++RE + FP
Sbjct: 365 DYDTLKAQIEEAGLNLDDYSWYLDLRKYGSVPHSGFGMGFERVIAWICKLDHVREAVPFP 424
Query: 431 RDRRRLVP 438
R R+ P
Sbjct: 425 RMINRMQP 432
>sp|P54262|SYN_LACDE ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRNA LIGASE) (ASNRS)
>gi|2145612|pir||S73326 asparagine--tRNA ligase (EC
6.1.1.22) asnS1 - Lactobacillus delbrueckii
>gi|1321875|emb|CAA61603.1| (X89438) asparagine--tRNA
ligase [Lactobacillus delbrueckii]
Length = 432
Score = 252 bits (638), Expect = 4e-66
Identities = 148/428 (34%), Positives = 237/428 (54%), Gaps = 17/428 (3%)
Query: 17 KKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVEG 76
++V++ W+ + + G I F+ +RD Q K V +E+F+ L E + G
Sbjct: 16 EEVRMHVWLTDKRSSGKIVFLQLRDGTAFFQGVVRKNDVSEEVFEAAKGLRQEASFYLTG 75
Query: 77 IVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPRVMSI 136
++ ++ G+EI LEV+S + P + +D LD+R + LR+ R +I
Sbjct: 76 TIHEDARSHFGYEIQISDLEVVSNNEGY----PITNKEHGIDFLLDHRHLWLRSRRPFAI 131
Query: 137 FKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFLAQSPQLYKQ 196
+IR+ +F+AT +FF EGF++ P ++ +A EG TELF + YF +DA+L+QS QLY +
Sbjct: 132 MQIRNRIFKATVDFFENEGFVKFDAPLLMHSAPEGTTELFHIDYFNHDAYLSQSGQLYGE 191
Query: 197 MMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYVIN 256
+ + K+F GP FRAE T RHL E W ++ EMA++ ++E +DL ER + YV+
Sbjct: 192 -VGAEAFGKIFTFGPTFRAEASKTRRHLTEFWMMEPEMAWMH-QDESLDLQERFLSYVVG 249
Query: 257 YVRENNEKELKILEFELNEPKKP----FPRITYDEALEILSDLGKEIPWGEDIDTEGEKL 312
V E+ E EL IL ++++ + + R++YD+A+++L + GK+ WG+D E
Sbjct: 250 QVLEHCEYELSILGRDVDKLRPAAEGNYTRLSYDDAVKMLQEAGKDFKWGDDFGAPDEAF 309
Query: 313 LGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEY-RGV-EISSGGQREH 370
L + + +FI YP KPFY+ K + P D+E G EI G +RE
Sbjct: 310 LSE-----QFDRPFFIVNYPVAIKPFYMKKNPENPLTYLCADVEAPEGYGEIMGGSEREA 364
Query: 371 RHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFP 430
+D L QI E GLN + + +YL +YG PH GFG+G ER+I + + ++RE + FP
Sbjct: 365 DYDTLKAQIEEAGLNLDDYSWYLDLRKYGSVPHSGFGMGFERVIAWICKLDHVREAVPFP 424
Query: 431 RDRRRLVP 438
R R+ P
Sbjct: 425 RMINRMQP 432
>dbj|BAB05415.1| (AP001512) asparaginyl-tRNA synthetase [Bacillus halodurans]
Length = 430
Score = 250 bits (631), Expect = 3e-65
Identities = 150/429 (34%), Positives = 237/429 (54%), Gaps = 19/429 (4%)
Query: 17 KKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVEG 76
++V + W+ + G I F+ +RD G +Q K +V E F+ L E + V G
Sbjct: 14 QEVTLGAWLANKRSSGKIAFLQLRDGTGFIQGVVVKAEVGDEWFQKAKNLTQESSLYVTG 73
Query: 77 IVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPRVMSI 136
IV +A G+E+ ++I +A T P+ P + + +D+R + +R+ + ++
Sbjct: 74 IVRKDERAPSGYELTVTSFDIIHEA-TDYPITPK---EHGTEFLMDHRHLWIRSRKQHAV 129
Query: 137 FKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFLAQSPQLYKQ 196
+IR+ + RAT EFF++ GF+++ P + +A EG TELF KYF+ DAFL+QS QLY +
Sbjct: 130 LRIRNEIIRATYEFFHENGFVKVDPPILTGSAPEGTTELFHTKYFDEDAFLSQSGQLYME 189
Query: 197 MMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYVIN 256
+ +VF GP FRAE+ T RHL E W I+ EMAF+E EE +++ E + Y++
Sbjct: 190 -AAALAFGRVFSFGPTFRAEKSKTRRHLIEFWMIEPEMAFVEFEES-LEIQENYVAYIVQ 247
Query: 257 YVRENNEKELKILEFE---LNEPKKPFPRITYDEALEILSDLG-KEIPWGEDIDTEGEKL 312
V ++ ELK L + L + PFPRI+YD+A++ L + G +I WG+D E
Sbjct: 248 SVLKHCAIELKTLGRDTSVLESIQAPFPRISYDDAIKFLHEKGFDDIEWGDDFGAPHETA 307
Query: 313 LGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDL---EYRGVEISSGGQRE 369
+ ++ + FI YP+ KPFY+ ++ +V DL E G EI G QR
Sbjct: 308 IAEHF-----DKPVFITHYPTSLKPFYMEPDPNRDDVVLCADLIAPEGYG-EIIGGSQRI 361
Query: 370 HRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILF 429
+D+L +++ E L+ +++ +YL +YG PH GFGLG ER + + G++RE I F
Sbjct: 362 SDYDLLKKRLEEHDLSLDAYAWYLDLRKYGSVPHSGFGLGLERTVGWISGAGHVRETIPF 421
Query: 430 PRDRRRLVP 438
PR RL P
Sbjct: 422 PRLLNRLYP 430
>sp|P54263|SYN_THETH ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRNA LIGASE) (ASNRS)
>gi|1004327|emb|CAA62491.1| (X91009) asparaginyl-tRNA
synthetase [Thermus thermophilus]
Length = 438
Score = 228 bits (575), Expect = 1e-58
Identities = 147/436 (33%), Positives = 236/436 (53%), Gaps = 25/436 (5%)
Query: 17 KKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVEG 76
++V++ GW+ + + G I F+ +RD G +Q T + +VP+ +F+ L E + V G
Sbjct: 14 QEVELRGWLYQRRSKGKIHFLILRDGTGFLQATVVQGEVPEAVFREADHLPQETALRVWG 73
Query: 77 IVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPRVMSI 136
V +A GFE+ L+V+S+ + P+ P + +D +D+R + LR+ R ++
Sbjct: 74 RVREDRRAPGGFELAVRDLQVVSRPQGEYPIGPK---EHGIDFLMDHRHLWLRHRRPFAV 130
Query: 137 FKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFEND-AFLAQSPQLYK 195
+IR + RA EFF + GF+ P + +A EG TELF ++ F+ + A+L+QS QLY
Sbjct: 131 MRIRDELERAIHEFFGERGFLRFDAPILTPSAVEGTTELFEVELFDGEKAYLSQSGQLYA 190
Query: 196 QMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYVI 255
+ + KV+ GP FRAE T RHL E W ++ E+AF+ EE M L E L+ +++
Sbjct: 191 EAG-ALAFAKVYTFGPTFRAERSKTRRHLLEFWMVEPEVAFMTHEEN-MALQEELVSFLV 248
Query: 256 NYVRENNEKELKIL--EFELNEPKKP--FPRITYDEALEILSDLGKE------IPWGEDI 305
V E +EL++L + + EP +PR+TY EA+ +++ + +E +P+GED
Sbjct: 249 ARVLERRSRELEMLGRDPKALEPAAEGHYPRLTYKEAVALVNRIAQEDPEVPPLPYGEDF 308
Query: 306 DTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDL---EYRGVEI 362
E L + F+ RYP+ K FY+ + PE+ DL E G EI
Sbjct: 309 GAPHEAALSRRF-----DRPVFVERYPARIKAFYMEPDPEDPELVLNDDLLRPEGYG-EI 362
Query: 363 SSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGN 422
G QR H ++L +I+E GL E +++YL +G PH GFGLG ER + + + +
Sbjct: 363 IGGSQRIHDLELLRRKIQEFGLPEEVYDWYLDLRRFGSVPHSGFGLGLERTVAWICGLAH 422
Query: 423 IREVILFPRDRRRLVP 438
+RE I FPR R+ P
Sbjct: 423 VREAIPFPRMYTRMRP 438
>sp|Q19722|SYN_CAEEL PROBABLE ASPARAGINYL-TRNA SYNTHETASE, CYTOPLASMIC (ASPARAGINE--TRNA
LIGASE) (ASNRS) >gi|7499656|pir||T21253 hypothetical
protein F22D6.3 - Caenorhabditis elegans
>gi|3876241|emb|CAA95808.1| (Z71262) predicted using
Genefinder~Similarity to Brugia asparaginyl-tRNA
synthetase (SW:63KD_BRUMA), contains similarity to Pfam
domain: PF00152 (tRNA synthetases class II (D, K and
N)), Score=452.1, E-value=1.6e-132, N=1~cDNA EST
EMBL:Z14941 comes fr>
Length = 545
Score = 196 bits (493), Expect = 4e-49
Identities = 134/435 (30%), Positives = 225/435 (50%), Gaps = 24/435 (5%)
Query: 17 KKVKVAGWVQEVKDLG-GIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVE 75
++V + WV ++ G + F+ +RD G +Q K + + + L++E + V
Sbjct: 122 QRVSIKAWVHRLRRQGKSLMFLVLRDGYGFLQCVLNDKLC--QSYDAVT-LSTETSVQVY 178
Query: 76 GIVNFTPKAKL---GFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPR 132
GI+ P K G E+ + EVI KA +D A +D LDNR + +R
Sbjct: 179 GIIKALPDGKSAPDGHELTVDYWEVIGKAPAG-GIDNVLNESAGVDVMLDNRHLVIRGEN 237
Query: 133 VMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFLAQSPQ 192
I +IR++ RA R+ F+ G+ E+ P ++ T EGG+ LF L Y+ A+L QS Q
Sbjct: 238 ASRILRIRAAATRAMRDHFFAAGYTEVAPPTLVQTQVEGGSTLFGLDYYGEPAYLTQSSQ 297
Query: 193 LYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLIL 252
LY + + L V+ I +RAE+ T RHL+E ++AE AFI + +++MD +E L+
Sbjct: 298 LYLE-TCNAALGDVYCISQSYRAEKSRTRRHLSEYQHVEAECAFI-TFDQLMDRIEALVC 355
Query: 253 YVINYVREN--NEKELKILEFELNEPKKPFPRITYDEALE------ILSDLGKEIPWGED 304
++ + + + ++ + P +PF R+ Y EA+E + +++G++ +GED
Sbjct: 356 DTVDRLLADPVTKSLIEFVNPGYKAPARPFKRMPYKEAIEWLQKNDVRNEMGEKFVYGED 415
Query: 305 IDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGV-EIS 363
I E + M + G + + R+P K FY+ + D E+ ++ DL GV EI
Sbjct: 416 IAEAAE----RRMTDTIGVPI-LLNRFPHGIKAFYMPRCADDNELTESVDLLMPGVGEIV 470
Query: 364 SGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNI 423
G R + D L+ + GL+ +++ +Y+ +YG PHGG+GLG ER I + D +I
Sbjct: 471 GGSMRIWKEDQLLAAFEKGGLDSKNYYWYMDQRKYGSVPHGGYGLGLERFICWLTDTNHI 530
Query: 424 REVILFPRDRRRLVP 438
R+V L+PR R P
Sbjct: 531 RDVCLYPRFVGRCAP 545
>gb|AAD55420.1|AF181634_1 (AF181634) BcDNA.GH06451 [Drosophila melanogaster]
>gi|7298549|gb|AAF53768.1| (AE003661) BcDNA:GH06451 gene
product [Drosophila melanogaster]
Length = 558
Score = 192 bits (482), Expect = 8e-48
Identities = 137/433 (31%), Positives = 227/433 (51%), Gaps = 23/433 (5%)
Query: 18 KVKVAGWVQEVKDLG-GIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVEG 76
+VKV GWV ++ G + FI +RD G +Q ++ Q L L++E +V+ G
Sbjct: 137 RVKVYGWVHRLRRQGKSLIFITLRDGTGFLQCVL-NDQLCQTYDALT--LSTESSVVLFG 193
Query: 77 IVNFTPKAKL---GFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPRV 133
+ P+ K G E+ + E+I A P D +A+ D +LDNR + +R
Sbjct: 194 TLKLVPEGKTAPGGHELNVDYWELIGLAP-PGGADAILNEEAQPDVQLDNRHIMIRGENT 252
Query: 134 MSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFLAQSPQL 193
+ K+RS V +A R + G+ E+ P ++ T EGG+ LF LKYF +A+L QS QL
Sbjct: 253 SKVLKMRSVVTQAFRGHYEARGYNEVTPPTLVQTQVEGGSTLFKLKYFGEEAYLTQSSQL 312
Query: 194 YKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILY 253
Y + + L VF I +RAE+ T RHL E ++AE F+ + ++++D LE L+
Sbjct: 313 YLETCL-PALGDVFTISQSYRAEQSRTRRHLAEYTHVEAECPFL-TFDDLLDRLEDLVCD 370
Query: 254 VINYVRENNEKEL-KILEFELNEPKKPFPRITYDEALE------ILSDLGKEIPWGEDID 306
V++ V ++ L K L + P+KPF R+ Y++A++ + D G +GEDI
Sbjct: 371 VVDRVLKSPWGYLVKELNPDFKPPQKPFRRMNYEDAIKWLKENNVTKDDGTFYEFGEDIP 430
Query: 307 TEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGV-EISSG 365
E+ + + E + R+P+E K FY+ + ++ + ++ D+ V EI G
Sbjct: 431 EAPER-----KMTDTINEPIMLCRFPAEIKSFYMQRCKEDQRLTESVDVLLPNVGEIVGG 485
Query: 366 GQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIRE 425
R + + L++ + +G++P+ + +Y YG PHGG+GLG ER + +L+ +IRE
Sbjct: 486 SMRIYDSEELLKGYKREGIDPQPYYWYTDQRVYGTMPHGGYGLGLERFLCWLLNRYHIRE 545
Query: 426 VILFPRDRRRLVP 438
V L+PR R P
Sbjct: 546 VCLYPRFLDRCRP 558
>gi|4758762 asparaginyl-tRNA synthetase [Homo sapiens]
>gi|3915059|sp|O43776|SYN_HUMAN ASPARAGINYL-TRNA
SYNTHETASE, CYTOPLASMIC (ASPARAGINE--TRNA LIGASE)
(ASNRS) >gi|2764505|emb|CAA04008.1| (AJ000334)
asparaginyl-tRNA synthetase [Homo sapiens]
>gi|3894218|dbj|BAA34600.1| (D84273) Asparaginyl tRNA
Synthetase [Homo sapiens]
Length = 548
Score = 191 bits (481), Expect = 1e-47
Identities = 134/439 (30%), Positives = 224/439 (50%), Gaps = 23/439 (5%)
Query: 12 EELNGKKVKVAGWVQEVKDLG-GIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSED 70
E G++VKV GWV ++ G + F+ +RD G +Q + L L++E
Sbjct: 121 EGYRGQRVKVFGWVHRLRRQGKNLMFLVLRDGTGYLQCVLADELCQCYNGVL---LSTES 177
Query: 71 VIVVEGIVNFTPKAKL---GFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMD 127
+ V G++N TPK K G E+ + E+I A D ++++D +L+NR M
Sbjct: 178 SVAVYGMLNLTPKGKQAPGGHELSCDFWELIGLAPAG-GADNLINEESDVDVQLNNRHMM 236
Query: 128 LRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFL 187
+R + I K RS V R R+ F+ G+ E+ P ++ T EGG LF L YF +AFL
Sbjct: 237 IRGENMSKILKARSMVTRCFRDHFFDRGYYEVTPPTLVQTQVEGGATLFKLDYFGEEAFL 296
Query: 188 AQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLL 247
QS QLY + + L VF I +RAE+ T RHL E ++AE F+ + +++++ L
Sbjct: 297 TQSSQLYLETCL-PALGDVFCIAQSYRAEQSRTRRHLAEYTHVEAECPFL-TFDDLLNRL 354
Query: 248 ERLILYVINYVRENNEKEL-KILEFELNEPKKPFPRITYDEAL------EILSDLGKEIP 300
E L+ V++ + ++ + L PK+PF R+ Y +A+ ++ + G
Sbjct: 355 EDLVCDVVDRILKSPAGSIVHELNPNFQPPKRPFKRMNYSDAIVWLKEHDVKKEDGTFYE 414
Query: 301 WGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGV 360
+GEDI E+L+ + E + R+P E K FY+ + + + ++ D+ V
Sbjct: 415 FGEDIPEAPERLMTDTI-----NEPILLCRFPVEIKSFYMQRCPEDSRLTESVDVLMPNV 469
Query: 361 -EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLD 419
EI G R + ++ + +G++P + +Y +YG PHGG+GLG ER + +L+
Sbjct: 470 GEIVGGSMRIFDSEEILAGYKREGIDPTPYYWYTDQRKYGTCPHGGYGLGLERFLTWILN 529
Query: 420 IGNIREVILFPRDRRRLVP 438
+IR+V L+PR +R P
Sbjct: 530 RYHIRDVCLYPRFVQRCTP 548
>gi|11426051 asparaginyl-tRNA synthetase [Homo sapiens]
Length = 572
Score = 191 bits (481), Expect = 1e-47
Identities = 134/439 (30%), Positives = 224/439 (50%), Gaps = 23/439 (5%)
Query: 12 EELNGKKVKVAGWVQEVKDLG-GIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSED 70
E G++VKV GWV ++ G + F+ +RD G +Q + L L++E
Sbjct: 145 EGYRGQRVKVFGWVHRLRRQGKNLMFLVLRDGTGYLQCVLADELCQCYNGVL---LSTES 201
Query: 71 VIVVEGIVNFTPKAKL---GFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMD 127
+ V G++N TPK K G E+ + E+I A D ++++D +L+NR M
Sbjct: 202 SVAVYGMLNLTPKGKQAPGGHELSCDFWELIGLAPAG-GADNLINEESDVDVQLNNRHMM 260
Query: 128 LRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFL 187
+R + I K RS V R R+ F+ G+ E+ P ++ T EGG LF L YF +AFL
Sbjct: 261 IRGENMSKILKARSMVTRCFRDHFFDRGYYEVTPPTLVQTQVEGGATLFKLDYFGEEAFL 320
Query: 188 AQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLL 247
QS QLY + + L VF I +RAE+ T RHL E ++AE F+ + +++++ L
Sbjct: 321 TQSSQLYLETCL-PALGDVFCIAQSYRAEQSRTRRHLAEYTHVEAECPFL-TFDDLLNRL 378
Query: 248 ERLILYVINYVRENNEKEL-KILEFELNEPKKPFPRITYDEAL------EILSDLGKEIP 300
E L+ V++ + ++ + L PK+PF R+ Y +A+ ++ + G
Sbjct: 379 EDLVCDVVDRILKSPAGSIVHELNPNFQPPKRPFKRMNYSDAIVWLKEHDVKKEDGTFYE 438
Query: 301 WGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGV 360
+GEDI E+L+ + E + R+P E K FY+ + + + ++ D+ V
Sbjct: 439 FGEDIPEAPERLMTDTI-----NEPILLCRFPVEIKSFYMQRCPEDSRLTESVDVLMPNV 493
Query: 361 -EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLD 419
EI G R + ++ + +G++P + +Y +YG PHGG+GLG ER + +L+
Sbjct: 494 GEIVGGSMRIFDSEEILAGYKREGIDPTPYYWYTDQRKYGTCPHGGYGLGLERFLTWILN 553
Query: 420 IGNIREVILFPRDRRRLVP 438
+IR+V L+PR +R P
Sbjct: 554 RYHIRDVCLYPRFVQRCTP 572
>sp|P75521|SYN_MYCPN ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRNA LIGASE) (ASNRS)
>gi|2146064|pir||S73906 asparagine--tRNA ligase (EC
6.1.1.22) asnS - Mycoplasma pneumoniae (strain ATCC
29342) >gi|1674281|gb|AAB96228.1| (AE000057)
asparaginyl-tRNA synthetase [Mycoplasma pneumoniae]
Length = 455
Score = 190 bits (479), Expect = 2e-47
Identities = 129/443 (29%), Positives = 222/443 (49%), Gaps = 33/443 (7%)
Query: 13 ELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVI 72
+ KK+K+ GW++ + I F+ + D ++ + A K+ E+F L ++ +
Sbjct: 15 QFKNKKIKLTGWLKNKRTSANIIFLEVNDGSTLLNLQAVVKQDQPELFALAESISLASAV 74
Query: 73 VVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPR 132
V G V TPK+K E++ +++ V+S A+ PL K + L+ +N ++ +R
Sbjct: 75 SVSGTVALTPKSKQPLELVVKQINVLSTARADYPLQ---KKEHSLEFFRNNAYLRVRART 131
Query: 133 VMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLK----YFENDAFLA 188
+I K+RS + +A ++F+K F+ +H+P + + EG E F LK +F +L
Sbjct: 132 YFAIMKVRSLLSQAIFDYFFKNDFVLVHSPILTSNDCEGAGETFELKQGKEFFNKTTYLT 191
Query: 189 QSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLE 248
S Q + + KVF GP FRAE+ +T+RHL+E W I+ E+AF + ++++ L+E
Sbjct: 192 VSGQ-FGAECYAQAFKKVFTFGPTFRAEKSHTSRHLSEFWMIEPEVAF-ANLKDLIKLIE 249
Query: 249 RLILYVINYVRENNEKELKILEFELN----------EPKKPFPRITYDEALEILSDLG-- 296
+ VI V + ++EL LE + + K F + Y +ALEIL
Sbjct: 250 STVKTVIKQVMQKAKQELDFLEKQFDVKLMERLKQITSTKNFHVLEYTKALEILKTAQAS 309
Query: 297 -------KEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEV 349
++ +G D+ TE E+ L + N+ F+ YP + K FY MK
Sbjct: 310 GQANFEVQDFNFGLDLKTEHERFLCEQHFHNQPV---FVINYPKDFKAFY-MKQNADGRT 365
Query: 350 CKAFDLEYRGV-EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGL 408
A DL + + EI G +RE + LVE+ + ++ ++ +YL ++G GFGL
Sbjct: 366 VGAVDLLFPQIGEICGGSEREGNLEKLVERCQAMQIDTQTLNWYLDMRKWGYFASAGFGL 425
Query: 409 GAERLIMRMLDIGNIREVILFPR 431
G +RL+ + + NIR+ I FPR
Sbjct: 426 GFDRLLAYICGLENIRDAIPFPR 448
>gi|6321807 Asparaginyl-tRNA synthetase; Ded81p [Saccharomyces cerevisiae]
>gi|731638|sp|P38707|SYNC_YEAST ASPARAGINYL-TRNA
SYNTHETASE, CYTOPLASMIC (ASPARAGINE--TRNA LIGASE)
(ASNRS) >gi|626599|pir||S46775 hypothetical protein
YHR019c - yeast (Saccharomyces cerevisiae)
>gi|500693|gb|AAB68874.1| (U10399) Ded81p:
Asparaginyl-tRNA synthetase [Saccharomyces cerevisiae]
Length = 554
Score = 189 bits (475), Expect = 6e-47
Identities = 129/439 (29%), Positives = 232/439 (52%), Gaps = 29/439 (6%)
Query: 16 GKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQ-VTAPKKKVPQEIFKLIPKLNSEDVIVV 74
G++VKV+GW+ ++ + F+ +RD G +Q V + + Q+ L E + +
Sbjct: 129 GQRVKVSGWIHRLRSNKKVIFVVLRDGSGFIQCVLSGDLALAQQTLDL----TLESTVTL 184
Query: 75 EGIVNFTPKAKL---GFEIIPEKLEVISKAKTPLPLDP-TGKVKAELDTRL--DNRFMDL 128
G + P+ K G E+ + EV+ A P D T K+ D L D R + L
Sbjct: 185 YGTIVKLPEGKTAPGGVELNVDYYEVVGLA--PGGEDSFTNKIAEGSDPSLLLDQRHLAL 242
Query: 129 RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFLA 188
R + ++ K+R+++ ++ R + +E E+ P ++ T EGG+ LF + Y+ +A+L
Sbjct: 243 RGDALSAVMKVRAALLKSVRRVYDEEHLTEVTPPCMVQTQVEGGSTLFKMNYYGEEAYLT 302
Query: 189 QSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLE 248
QS QLY + +++ L V+ I FRAE+ +T RHL+E I+AE+AF+ + ++++ +E
Sbjct: 303 QSSQLYLETCLAS-LGDVYTIQESFRAEKSHTRRHLSEYTHIEAELAFL-TFDDLLQHIE 360
Query: 249 RLILYVINYVREN--NEKELKILEFELNEPKKPFPRITYDEAL------EILSDLGKEIP 300
LI+ + YV E+ +K L PK PF R+ Y +A+ +I ++ G++
Sbjct: 361 TLIVKSVQYVLEDPIAGPLVKQLNPNFKAPKAPFMRLQYKDAITWLNEHDIKNEEGEDFK 420
Query: 301 WGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGV 360
+G+DI E + M + G + F+ R+P E K FY+ + D P V ++ D+ V
Sbjct: 421 FGDDIAEAAE----RKMTDTIGVPI-FLTRFPVEIKSFYMKRCSDDPRVTESVDVLMPNV 475
Query: 361 -EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLD 419
EI+ G R D L+ + +G++ +++ +++ +YG PHGG+G+G ER++ + D
Sbjct: 476 GEITGGSMRIDDMDELMAGFKREGIDTDAYYWFIDQRKYGTCPHGGYGIGTERILAWLCD 535
Query: 420 IGNIREVILFPRDRRRLVP 438
+R+ L+PR R P
Sbjct: 536 RFTVRDCSLYPRFSGRCKP 554
>sp|P47359|SYN_MYCGE ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRNA LIGASE) (ASNRS)
>gi|1361447|pir||E64212 asparagine--tRNA ligase (EC
6.1.1.22) - Mycoplasma genitalium
>gi|3844702|gb|AAC71331.1| (U39691) asparaginyl-tRNA
synthetase (asnS) [Mycoplasma genitalium]
Length = 456
Score = 189 bits (474), Expect = 7e-47
Identities = 135/444 (30%), Positives = 220/444 (49%), Gaps = 34/444 (7%)
Query: 13 ELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGI--VQVTAPKKKVPQEIFKLIPKLNSED 70
+ N K++K++GWV+ + I F+ I D I +Q ++ PQ +F L+ +N
Sbjct: 15 KFNNKQIKLSGWVKNKRASANIIFLAISDGSSINTLQAVVKQEDNPQ-VFSLLQTVNLAS 73
Query: 71 VIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRN 130
++V G + TPKAK E+ +++ ++++A++ PL K + + N + +R
Sbjct: 74 AVMVWGEIILTPKAKQPLELKLKQVSLLAQAESDYPLQ---KKEHSQEFFRSNAHLRVRA 130
Query: 131 PRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLK----YFENDAF 186
++ KIRS + A E+F+K FI + +P + + EG E F +K +F F
Sbjct: 131 KTYFAVMKIRSVLSHAIFEYFFKNDFILVQSPILTSNDCEGAGETFVIKDSETFFNKTTF 190
Query: 187 LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDL 246
L S Q + + KVF GP FRAE+ +T RHL+E W I+ E+AF ++ +M L
Sbjct: 191 LTVSGQFGAEAF-AQAFKKVFTFGPTFRAEKSHTNRHLSEFWMIEPEIAFANLKD-LMQL 248
Query: 247 LERLILYVINYVRENNEKELKILEFELNEP----------KKPFPRITYDEALEIL---S 293
++ LI ++I V EN EL +L + + K FP I Y +AL IL S
Sbjct: 249 IQNLIKFLIKKVMENASDELNVLAKQFSNDIISNLKTIISTKKFPIIEYSKALAILKESS 308
Query: 294 DLGK------EIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKP 347
D K + +G D+ TE E+ L + +N+ F+ YP E K FY+ D
Sbjct: 309 DTKKTNFELNDFSFGIDLKTEHERFLCEQYFQNQPL---FVINYPKELKAFYMKTNTDNK 365
Query: 348 EVCKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFG 407
V L + EI G +RE + L + + ++ +S +YL ++G GFG
Sbjct: 366 TVAAVDLLLPKIGEICGGSERESDLNQLKNRCQSLNIDTKSLNWYLDMRKWGYFASAGFG 425
Query: 408 LGAERLIMRMLDIGNIREVILFPR 431
LG +RL+ + + NIR+ I FPR
Sbjct: 426 LGFDRLLAYICGLENIRDAIPFPR 449
>sp|P43829|SYN_HAEIN ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRNA LIGASE) (ASNRS)
>gi|1073865|pir||B64115 asparagine--tRNA ligase (EC
6.1.1.22) - Haemophilus influenzae (strain Rd KW20)
>gi|1574761|gb|AAC22949.1| (U32810) asparaginyl-tRNA
synthetase (asnS) [Haemophilus influenzae Rd]
Length = 477
Score = 183 bits (459), Expect = 4e-45
Identities = 135/459 (29%), Positives = 218/459 (47%), Gaps = 53/459 (11%)
Query: 16 GKKVKVAGWVQEVKDL-GGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVV 74
G+ V V GWV+ +D G+ F+ + D + A + I +L + ++V
Sbjct: 28 GETVTVRGWVRTRRDSKAGLSFLAVYDGSCFDPIQAIINNDIENYESEILRLTTGCSVIV 87
Query: 75 EGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPRVM 134
G V +P E+ EK+EV + P P + ++ + + R +
Sbjct: 88 TGKVVESPAEGQAVELQAEKVEVTGFVEDP-DTYPMAAKRHSIEYLREVAHLRPRTNIIG 146
Query: 135 SIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLK--------------- 179
++ ++R + +A FF+++GF + TP I A+ TEG E+F +
Sbjct: 147 AVARVRHCLSQAIHRFFHEQGFYWVATPLITASDTEGAGEMFRVSTLDLENLPRSENGKV 206
Query: 180 -----YFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEM 234
+F ++FL S QL + + L K++ GP FRAE NTTRHL E W ++ E+
Sbjct: 207 DFSQDFFGKESFLTVSGQLNGETY-ACALSKIYTFGPTFRAENSNTTRHLAEFWMVEPEV 265
Query: 235 AFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEP---------KKPFPRITY 285
AF + L E ++ YV V + +L+ E +++ F +I Y
Sbjct: 266 AFATLADNAK-LAEDMLKYVFRAVLAERKDDLQFFEKHVDKDVITRLENFVNSDFAQIDY 324
Query: 286 DEALEILSDLGKE----IPWGEDIDTEGEKLLGKYMLENEGAELYF-----IYRYPSEAK 336
+A+++L GK+ + WG D+ +E E+ L AE YF + YP + K
Sbjct: 325 TDAIDVLLKSGKKFEFPVSWGIDLSSEHERFL---------AEEYFKSPVVVKNYPKDIK 375
Query: 337 PFYIMKYEDKPEVCKAFDLEYRGV-EISSGGQREHRHDILVEQIREKGLNPESFEFYLRA 395
FY M+ D + A D+ G+ EI G QRE R ++L +++ E GLNP+ + +Y
Sbjct: 376 AFY-MRLNDDEKTVAAMDVLAPGIGEIIGGSQREERLEVLDKRMEEMGLNPDDYWWYRDL 434
Query: 396 FEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRR 434
+YG PH GFGLG ERLI+ + + NIR+VI FPR R
Sbjct: 435 RKYGSVPHSGFGLGFERLIVYVTGVQNIRDVIPFPRAPR 473
>pir||A82901 asparaginyl-tRNA synthetase UU365 [imported] - Ureaplasma
urealyticum >gi|6899346|gb|AAF30774.1|AE002133_7
(AE002133) asparaginyl-tRNA synthetase [Ureaplasma
urealyticum]
Length = 454
Score = 181 bits (455), Expect = 1e-44
Identities = 126/447 (28%), Positives = 216/447 (48%), Gaps = 32/447 (7%)
Query: 13 ELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVI 72
+L G+K+++ WV+ +D I F+ + D + + A + + ++ I +
Sbjct: 15 KLEGQKIQIKAWVRSNRDSKKIGFLVLNDGSSLTNLQAVYRVDKIDNYEEIAAARMWAAV 74
Query: 73 VVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPR 132
V+EG++ TP AK E+ +++ ++ L L+T N + R
Sbjct: 75 VIEGVIKLTPTAKQPLELEVLNAQILKQSDEDFLLSNND---LNLETLRLNAHLRPRTNL 131
Query: 133 VMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFLAQSPQ 192
+I K+R+++ A EF + + + P EG E F ++ F+N+ F +
Sbjct: 132 FHAIMKVRATLAFAVHEFMNQNEYSWLAAPLFTGNDAEGAGETFSIQKFDNEEFFGKQTH 191
Query: 193 L-----YKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLL 247
L + + V+ GP FRAE+ +T RHL E W I+ EMAF++ + + D++
Sbjct: 192 LSVTGQLQAEAYAQAFGNVYTFGPTFRAEKSHTNRHLAEFWMIEPEMAFVDLKG-MQDIV 250
Query: 248 ERLILYVINYVRENNEKELKILEFELNEP---------KKPFPRITYDEALEILSDLGK- 297
E L+ +VI V E N++EL+ L +E + F RI Y +A++IL+D K
Sbjct: 251 EDLVKHVIKAVLEKNQQELEFLAQRNDENLIKKLQKVVESKFERIEYKDAVKILADAVKN 310
Query: 298 -------EIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVC 350
EI +G D+ +E E+ YM E F+ YP + K FY MK D +
Sbjct: 311 GHQFENNEIFFGMDLGSEHER----YMCETYHQGPVFLQNYPKDIKAFY-MKLNDDQQTV 365
Query: 351 KAFDLEYRGV-EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLG 409
+ DL GV E+ G QRE ++ L+++ +E + ES ++YL +G GFG+G
Sbjct: 366 ASTDLLIPGVGELVGGSQREDSYEKLLKRCQELKMPIESLQWYLDLRRFGYYMSSGFGIG 425
Query: 410 AERLIMRMLDIGNIREVILFPRDRRRL 436
ERL+M + + NI++ I FPR ++
Sbjct: 426 FERLVMYVTGVNNIKDTIPFPRSHGQI 452
>sp|P10723|SYN_BRUMA ASPARAGINYL-TRNA SYNTHETASE, CYTOPLASMIC (ASPARAGINE--TRNA LIGASE)
(ASNRS) (POTENTIALLY PROTECTIVE 63 KD ANTIGEN)
>gi|627105|pir||A54510 63K antigen - nematode (Brugia
malayi) >gi|156057|gb|AAA27852.1| (J03971) 63 kd antigen
[Brugia malayi]
Length = 548
Score = 181 bits (454), Expect = 2e-44
Identities = 129/435 (29%), Positives = 224/435 (50%), Gaps = 24/435 (5%)
Query: 17 KKVKVAGWVQEVKDLG-GIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVE 75
++V + GW+ ++ G + F +RD G +QV K+ Q L +N+E + +
Sbjct: 125 ERVCIKGWIHRMRRQGKSLMFFILRDGTGFLQVLL-MDKLCQTYDALT--VNTECTVEIY 181
Query: 76 GIVNFTPKAKL---GFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPR 132
G + P+ K G E+I + ++I A P +D +A +D LDNR + +R
Sbjct: 182 GAIKEVPEGKEAPNGHELIADFWKIIGNAP-PGGIDNVLNEEASVDKMLDNRHLVIRGEN 240
Query: 133 VMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFLAQSPQ 192
++ ++R++ RA RE FY G++E+ P ++ T EGG+ LF L YF +FL QS Q
Sbjct: 241 AAALLRLRAAATRAMREHFYNAGYLEVAPPTLVQTQVEGGSTLFNLDYFGEQSFLTQSSQ 300
Query: 193 LYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLIL 252
LY + + T L VF + + + + + L E ++AE FI + +++M+ +E L+
Sbjct: 301 LYLETCIPT-LGDVFLHCSVLQGGKISHSSTLAEYAHVEAECPFI-TLDDLMEKIEELVC 358
Query: 253 YVINYVRENNE--KELKILEFELNEPKKPFPRITYDEALEIL------SDLGKEIPWGED 304
++ + + E K L+ + + P++PF R+ Y +A++ L ++ G +GED
Sbjct: 359 DTVDRLLADEEAKKLLEHINPKFQPPERPFLRMEYKDAIKWLQEHNVENEFGNTFTYGED 418
Query: 305 IDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGV-EIS 363
I E ++M + + + R+PSE K FY+ + + ++ DL GV EI
Sbjct: 419 IAEAAE----RFMTDTINKPI-LLNRFPSEIKAFYMQRDAQDNTLTESVDLLMPGVGEIV 473
Query: 364 SGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNI 423
G R + D L + + ++P+ + +YL YG PHGG+GLG ER I + + +I
Sbjct: 474 GGSMRIWKFDELSKAFKNVEIDPKPYYWYLDQRLYGTCPHGGYGLGLERFICWLTNTNHI 533
Query: 424 REVILFPRDRRRLVP 438
R+V L+PR R VP
Sbjct: 534 RDVCLYPRFVGRCVP 548
>sp|P17242|SYN_ECOLI ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRNA LIGASE) (ASNRS)
>gi|68529|pir||SYECNT asparagine--tRNA ligase (EC
6.1.1.22) - Escherichia coli >gi|41000|emb|CAA48274.1|
(X68192) Asparaginyl-tRNA synthetase [Escherichia coli]
>gi|147935|gb|AAA24666.1| (M33145) asparaginyl-tRNA
synthetase (asnS) [Escherichia coli]
>gi|1651455|dbj|BAA35682.1| (D90731) Asparaginyl-tRNA
synthetase (EC 6.1.1.22) (asparagine-tRNA ligase)
(asnRS). [Escherichia coli] >gi|1787161|gb|AAC74016.1|
(AE000195) asparagine tRNA synthetase [Escherichia coli
K12]
Length = 466
Score = 180 bits (452), Expect = 3e-44
Identities = 133/452 (29%), Positives = 213/452 (46%), Gaps = 43/452 (9%)
Query: 18 KVKVAGWVQEVKDL-GGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVEG 76
+V V GWV+ +D GI F+ + D V A + + +L + ++V G
Sbjct: 19 EVTVRGWVRTRRDSKAGISFLAVYDGSCFDPVQAVINNSLPNYNEDVLRLTTGCSVIVTG 78
Query: 77 IVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPRVMSI 136
V +P FEI K+EV + P P + ++ + + R + ++
Sbjct: 79 KVVASPGQGQQFEIQASKVEVAGWVEDP-DTYPMAAKRHSIEYLREVAHLRPRTNLIGAV 137
Query: 137 FKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLK----------------- 179
++R ++ +A FF ++GF + TP I A+ TEG E+F +
Sbjct: 138 ARVRHTLAQALHRFFNEQGFFWVSTPLITASDTEGAGEMFRVSTLDLENLPRNDQGKVDF 197
Query: 180 ---YFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAF 236
+F ++FL S QL + + L K++ GP FRAE NT+RHL E W ++ E+AF
Sbjct: 198 DKDFFGKESFLTVSGQLNGETY-ACALSKIYTFGPTFRAENSNTSRHLAEFWMLEPEVAF 256
Query: 237 IESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEP---------KKPFPRITYDE 287
+ + L E ++ YV V E ++K +++ + F ++ Y +
Sbjct: 257 ANLND-IAGLAEAMLKYVFKAVLEERADDMKFFAERVDKDAVSRLERFIEADFAQVDYTD 315
Query: 288 ALEILSDLGKE----IPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKY 343
A+ IL + G++ + WG D+ +E E+ Y+ E + YP + K FY+
Sbjct: 316 AVTILENCGRKFENPVYWGVDLSSEHER----YLAEEHFKAPVVVKNYPKDIKAFYMRLN 371
Query: 344 EDKPEVCKAFDLEYRGV-EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPP 402
ED V A D+ G+ EI G QRE R D+L E++ E GLN E + +Y YG P
Sbjct: 372 EDGKTVA-AMDVLAPGIGEIIGGSQREERLDVLDERMLEMGLNKEDYWWYRDLRRYGTVP 430
Query: 403 HGGFGLGAERLIMRMLDIGNIREVILFPRDRR 434
H GFGLG ERLI + + N+R+VI FPR R
Sbjct: 431 HSGFGLGFERLIAYVTGVQNVRDVIPFPRTPR 462
>pir||T39675 asparaginyl-trna synthetase - fission yeast (Schizosaccharomyces
pombe) >gi|3850088|emb|CAA21915.1| (AL033389)
asparaginyl-trna synthetase, cytoplasmic
[Schizosaccharomyces pombe]
Length = 568
Score = 180 bits (452), Expect = 3e-44
Identities = 127/438 (28%), Positives = 211/438 (47%), Gaps = 29/438 (6%)
Query: 18 KVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVEGI 77
+V+V GWV ++ GI FI +RD G +Q K + + I L E + + G+
Sbjct: 143 RVRVNGWVHRMRTQKGIIFIILRDGTGFLQCVLSGKVYDRASYDFI-NLGPESTVCLYGV 201
Query: 78 VNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGK--------VKAELDTRLDNRFMDLR 129
+ P+ K P E++ L PTG+ +AE LD R + +R
Sbjct: 202 IKELPEGKSA----PGNHELVVDYYQILHAAPTGEEAFTNRLNAEAEPSYLLDQRHLVIR 257
Query: 130 NPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFLAQ 189
S+ K+R+ RA R+ F E+ P ++ T EGG LF Y+ DA+L Q
Sbjct: 258 GETASSVLKVRARALRAMRDTFENLKMTEVTPPCMVQTQVEGGATLFKFNYYGQDAYLTQ 317
Query: 190 SPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLER 249
S QLY + + L V+ I FRAE+ T RHL+E ++ E+ F+ + E ++++E
Sbjct: 318 SSQLYLEAAL-PALGSVYTIQESFRAEKSLTRRHLSEFTHVEFELPFV-NFGEFLEIIEE 375
Query: 250 LILYVINYVREN--NEKELKILEFELNEPKKPFPRITYDEALE------ILSDLGKEIPW 301
I I+ + ++ +K L + +P +PF R++Y++A++ IL+ G++ +
Sbjct: 376 FICQTIDRLLDDPIATPLIKQLNPDFVKPSRPFMRLSYEDAIKYLNEHNILTPEGEQHKF 435
Query: 302 GEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGV- 360
G+DI E + M + ++ Y +P E K FY+ + D+PE+ ++ D V
Sbjct: 436 GDDIAEAAE----RKMTDQINRPIFLTY-FPLEIKSFYMKRVVDRPELTESVDCLMPNVG 490
Query: 361 EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDI 420
EI G R L+ + +G++P + ++ +YG HGG GLG ER + + D
Sbjct: 491 EIVGGSMRISDIQELLAAYKREGIDPAPYYWFTEQRKYGTTEHGGCGLGLERFLAWLCDR 550
Query: 421 GNIREVILFPRDRRRLVP 438
+RE LFPR R P
Sbjct: 551 YTVRECCLFPRFTERCTP 568
>emb|CAB91185.1| (AL355921) asparaginyl-trna synthetase, mitochondrial
[Schizosaccharomyces pombe]
Length = 441
Score = 180 bits (451), Expect = 4e-44
Identities = 136/447 (30%), Positives = 219/447 (48%), Gaps = 61/447 (13%)
Query: 15 NGKKVKVAGWVQEVKDLGGIKFIWIRD---REGIVQVTAPKKKVPQEIFKLIPKLNSEDV 71
NG+ + + GWV+ ++ L + F + D ++ + VT+P++ KL+
Sbjct: 19 NGELISINGWVRSIRKLKNVCFAMVSDGTCQQALQVVTSPEQS---------KKLSYGAS 69
Query: 72 IVVEGIVNFTPKAKLG---FEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRF--M 126
+ +EG + + AKLG +E++ EK+++ + D K L T + + +
Sbjct: 70 VNIEGQLAVSKNAKLGLQQYELLAEKIKIYGQIND----DNYPIQKKHLTTEMLRQIPHL 125
Query: 127 DLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLK------- 179
LR + IF++RS +A R+FF + F E + P I ++ EG E+F L
Sbjct: 126 RLRTAKQGEIFRLRSDSLKALRQFFSSKDFTETNPPIITSSDCEGAGEVFTLTPQETHKN 185
Query: 180 ----------YFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWS 229
+F+ AFL S QL+ + + + GL +V+ I P FRAE+ +T+RHL E W
Sbjct: 186 KSFERDDQKHFFDRPAFLTVSTQLHLEAL-ALGLSRVYTISPAFRAEQSHTSRHLAEFWM 244
Query: 230 IDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEAL 289
++AE+AF+ S ++ L+E +I Y +N + E N ++ KP+ +TY EA+
Sbjct: 245 LEAEVAFMTSLSQLTSLMEDMIKYTLNSLMEQNYH-----RDHWDQLLKPWKCMTYSEAI 299
Query: 290 EILSDLGK--EIP--WGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYED 345
E LS + K + P WG D+ +E E KY+ E F+ YP + KPFY+
Sbjct: 300 EELSAVKKTWKYPPKWGNDLSSEHE----KYLCEILHKTPVFVTDYPQKIKPFYMK--SS 353
Query: 346 KPEVCKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGG 405
P+ A DL V +GG H + E P ++YL +Y PHGG
Sbjct: 354 GPDTVAAVDLLVPQVGELAGGSLRKDH------LDEYKTYPPELQWYLDLMKYSNAPHGG 407
Query: 406 FGLGAERLIMRML-DIGNIREVILFPR 431
FGLG ERLI + + N++E I FPR
Sbjct: 408 FGLGIERLIAFLEGENTNVKETIPFPR 434
>pir||A28209 60K filarial antigen - nematode (Brugia malayi)
>gi|156053|gb|AAA27849.1| (J03266) 63kd antigen [Brugia
malayi]
Length = 548
Score = 179 bits (450), Expect = 5e-44
Identities = 128/435 (29%), Positives = 224/435 (51%), Gaps = 24/435 (5%)
Query: 17 KKVKVAGWVQEVKDLG-GIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVE 75
++V + GW+ ++ G + F +RD G +QV K+ Q L +N+E + +
Sbjct: 125 ERVCIKGWIHRMRRQGKSLMFFILRDGTGFLQVLL-MDKLCQTYDALT--VNTECTVEIY 181
Query: 76 GIVNFTPKAKL---GFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPR 132
G + P+ K G E+I + ++I A + +D +A +D LDNR + +R
Sbjct: 182 GAIKEVPEGKEAPNGHELIADFWKIIGNAPSG-GIDNVLNEEASVDKMLDNRHLVIRGEN 240
Query: 133 VMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFLAQSPQ 192
++ ++R++ RA RE FY G++E+ P ++ T EGG+ LF L YF +FL QS Q
Sbjct: 241 AAALLRLRAAATRAMREHFYNAGYVEVAPPTLVQTQVEGGSTLFNLDYFGEQSFLTQSSQ 300
Query: 193 LYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLIL 252
LY + + T L VF + + + + + L E ++AE FI + +++M+ +E L+
Sbjct: 301 LYLETCIPT-LGDVFLHCSVLQGGKISHSSTLAEYAHVEAECPFI-TLDDLMEKIEELVC 358
Query: 253 YVINYVRENNE--KELKILEFELNEPKKPFPRITYDEALEIL------SDLGKEIPWGED 304
++ + + E K L+ + + P++PF R+ Y +A++ L ++ G +GED
Sbjct: 359 DTVDRLLADEEAKKLLEHINPKFQPPERPFLRMEYKDAIKWLQEHNVENEFGNTFTYGED 418
Query: 305 IDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGV-EIS 363
I E ++M + + + R+PSE K FY+ + + ++ DL GV EI
Sbjct: 419 IAEAAE----RFMTDTINKPI-LLNRFPSEIKAFYMQRDAKDNTLTESVDLLMPGVGEIV 473
Query: 364 SGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNI 423
G R + D L + + ++P+ + +YL YG PHGG+GLG ER I + + +I
Sbjct: 474 GGSMRIWKFDELSKAFKNVEIDPKPYYWYLDQRLYGTCPHGGYGLGLERFICWLTNTNHI 533
Query: 424 REVILFPRDRRRLVP 438
R+V L+PR R VP
Sbjct: 534 RDVCLYPRFVGRCVP 548
>sp|P52276|SYN_SYNY3 PROBABLE ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRNA LIGASE)
(ASNRS) >gi|7437579|pir||S75997 asparagine--tRNA ligase
(EC 6.1.1.22) - Synechocystis sp. (strain PCC 6803)
>gi|1001357|dbj|BAA10844.1| (D64006) asparaginyl-tRNA
synthetase [Synechocystis sp.]
Length = 513
Score = 178 bits (447), Expect = 1e-43
Identities = 123/446 (27%), Positives = 207/446 (45%), Gaps = 40/446 (8%)
Query: 18 KVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVEGI 77
+V V GW++ + L F+ + D + + + +L+ +L + +VVEG
Sbjct: 69 QVMVQGWLRTKRTLKDFSFVEVNDGSSLANLQVVLDGSLADYDRLLSQLQTGAALVVEGK 128
Query: 78 VNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPRVMSIF 137
+ +P E+ KLE++ A P K + + + R + ++
Sbjct: 129 LAPSPGKGQRVELKATKLELLGGADPGSY--PLQKKRHSFEFLRTIGHLRPRTNTIGAVM 186
Query: 138 KIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLK------------------ 179
++R++ A +FF + GF+ +HTP I A+ EG +LF +
Sbjct: 187 RVRNACATAIHQFFQERGFLWVHTPIITASDCEGAGDLFKVTTLDLQRVPKNGEGIDYSQ 246
Query: 180 -YFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIE 238
+F A+L S QL ++M + V+ GP FRAE NT+RHL E W ++ EMAF +
Sbjct: 247 DFFGKQAYLTVSGQLEAEVM-ALAFQNVYTFGPTFRAENSNTSRHLAEFWMVEPEMAFCD 305
Query: 239 SEEEVMDLLERLILYVINYVRENNEKELKILEFELNEP---------KKPFPRITYDEAL 289
E + E + Y+ +V E ++++ + ++ F +TY EA+
Sbjct: 306 LEGD-RQWAEEFLKYIFKFVLEKCPEDMEFFDQRIDNTVLATADNIINNEFAWLTYSEAI 364
Query: 290 EILSDLGKE----IPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYED 345
++L ++ + WG D+ +E E+ Y+ E + YP + K FY+ +D
Sbjct: 365 KLLEKADQKFEYPVAWGVDLQSEHER----YLAETVFKRPTIVTDYPKDIKAFYMRLNDD 420
Query: 346 KPEVCKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGG 405
V L + EI G QRE R DIL ++++E+G+ E +YL YG PH G
Sbjct: 421 GKTVAAMDILAPKIGEIIGGSQREERLDILTQRMQEQGVPEEDLWWYLDLRRYGSVPHAG 480
Query: 406 FGLGAERLIMRMLDIGNIREVILFPR 431
FGLG ER++ M + NIR+VI FPR
Sbjct: 481 FGLGFERIVQFMTGMANIRDVIPFPR 506
>pir||E82217 asparaginyl-tRNA synthetase VC1297 [imported] - Vibrio cholerae
(group O1 strain N16961) >gi|9655785|gb|AAF94456.1|
(AE004209) asparaginyl-tRNA synthetase [Vibrio cholerae]
Length = 481
Score = 178 bits (447), Expect = 1e-43
Identities = 131/465 (28%), Positives = 215/465 (46%), Gaps = 48/465 (10%)
Query: 10 ITEELNGK-----KVKVAGWVQEVKDL-GGIKFIWIRDREGIVQVTAPKKKVPQEIFKLI 63
+ + L+GK +V V GW++ +D GI F+ I D + A +
Sbjct: 21 VNDVLSGKLAVDSEVTVRGWIRTRRDSKAGISFLAIYDGSCFNPIQAVVPNNLNNYDNEV 80
Query: 64 PKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDN 123
KL + + V G + +P + FE+ ++V+ + P K + ++ +
Sbjct: 81 LKLTTGCSVEVTGKIVESPASGQAFELAASDVKVVGWVEDA-DTYPMAKTRHSIEYLREV 139
Query: 124 RFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLK---- 179
+ R + ++ ++R+ + +A F++++G+ + P I A+ EG E+F +
Sbjct: 140 AHLRPRTNVIGAVARVRNCLAQAIHRFYHEQGYFWVSAPLITASDAEGAGEMFRVSTLDM 199
Query: 180 ----------------YFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRH 223
+F + FL S QL + + + KV+ GP FRAE NT+RH
Sbjct: 200 ENLPRTDAGKVDYNQDFFGKETFLTVSGQLNAEAY-ACAISKVYTFGPTFRAENSNTSRH 258
Query: 224 LNEAWSIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEP------- 276
L E W ++ E+AF + V L E ++ YV V +L+ +N
Sbjct: 259 LAEFWMVEPEVAFADLNT-VAKLAEDMLKYVFKAVLAERRDDLEFFNDRINNEVIARLEQ 317
Query: 277 --KKPFPRITYDEALEILSDLGKE----IPWGEDIDTEGEKLLGKYMLENEGAELYFIYR 330
+ F ++ Y +A+EIL + GK + WG D+ +E E+ L E +
Sbjct: 318 FVESDFAQVDYTDAIEILKNCGKTFEFPVEWGIDLASEHERFLA----EEHFKAPVIVKN 373
Query: 331 YPSEAKPFYIMKYEDKPEVCKAFDLEYRGV-EISSGGQREHRHDILVEQIREKGLNPESF 389
YP + K FY+ ED V A D+ G+ EI G QRE R DIL ++RE G++PE
Sbjct: 374 YPKDIKAFYMRMNEDGKTVA-AMDVLAPGIGEIIGGSQREERLDILDARMREFGIDPEHM 432
Query: 390 EFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRR 434
++Y YG PH GFGLG ERL+ + +GN+R+VI FPR R
Sbjct: 433 DWYRDLRRYGTVPHAGFGLGFERLVSYVTGMGNVRDVIPFPRTPR 477
>sp|O67589|SYD_AQUAE ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|7437585|pir||D70445 aspartate--tRNA ligase (EC
6.1.1.12) - Aquifex aeolicus >gi|2984003|gb|AAC07548.1|
(AE000750) aspartyl-tRNA synthetase [Aquifex aeolicus]
Length = 603
Score = 171 bits (430), Expect = 1e-41
Identities = 122/302 (40%), Positives = 169/302 (55%), Gaps = 36/302 (11%)
Query: 3 RTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKL 62
RT Y E++EE GK+VK+AGWV + GG+ FI +RDREGIVQV +K P E +++
Sbjct: 10 RTKYCGEVSEEDIGKEVKLAGWVHRKRHHGGVIFIDLRDREGIVQVVVEEKTNP-EAYEV 68
Query: 63 IPKLNSEDVIVVEGIV------NFTPKAKLGF-EIIPEKLEVISKAKT-PLPLDPTGKVK 114
KL SE VI V G V PK K G+ E++ +++ V + ++ P P++ V
Sbjct: 69 ADKLKSEYVIGVVGKVRKRPEGTENPKLKTGYVEVVADRILVFNTSEALPFPVEEETHVS 128
Query: 115 AELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGG-- 172
E T+L R++DLR + + R V++ TR FF KEGFIEI TP + + EG
Sbjct: 129 EE--TKLKYRYIDLRRESMKNNLIFRHRVYQITRNFFTKEGFIEIETPFLTKSTPEGARD 186
Query: 173 ----TELFPLKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAW 228
+ L P K++ L QSPQL+KQ++M G D+ F+I FR E+ R E
Sbjct: 187 FLVPSRLHPGKFYA----LPQSPQLFKQILMIAGFDRYFQIVKCFRDEDLRADRQ-PEFT 241
Query: 229 SIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEA 288
ID EM+F+ SEEEVMD+ ERLI + KEL +E K PF RI+Y EA
Sbjct: 242 QIDYEMSFV-SEEEVMDVAERLIATLF--------KELLGVEL-----KTPFERISYREA 287
Query: 289 LE 290
+E
Sbjct: 288 ME 289
Score = 70.2 bits (169), Expect = 4e-11
Identities = 74/303 (24%), Positives = 123/303 (40%), Gaps = 63/303 (20%)
Query: 194 YKQMMMSTGLDK--------VFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMD 245
Y++ M G DK + E+ IF+ + + EA I + F S +
Sbjct: 284 YREAMEKYGTDKPDRRFGLELIELTDIFKNTAFKVFKSVVEAGGIIKAINFKGS-----N 338
Query: 246 LLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIP----- 300
L + I + +V+ K L ++ E ++ P + +E + L + K P
Sbjct: 339 LSRKEIDELTKFVQSLGAKGLAWIKVEKDKLTSPIVKFFTEEETQKLLERTKAEPGDVIL 398
Query: 301 WGEDIDTEGEKLLG--------KYMLENEGA-ELYFIYRYP------------SEAKPFY 339
+ D K+LG KY L +E ++++I +P S PF
Sbjct: 399 FSADKKEMVYKILGNLRLHLGKKYKLIDESKWDVFWIVDFPLMEWDEEEERFVSLHHPFT 458
Query: 340 IMKYEDKPEV--------------------CKAFDLEYRGVEISSGGQREHRHDILVEQI 379
+ + E+ P++ +A+D+ G EI G R HR DI
Sbjct: 459 MPREENIPKLKEALEEEDLEKKKEIVHSVRARAYDMVLNGEEIGGGSIRIHRRDIQEVVF 518
Query: 380 REKGLNP----ESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRRR 435
+ G+ E F F L A +YG PPHGG G +R++ ML + +IR+ I FP+ +R
Sbjct: 519 KLLGIGEVEAQEKFGFLLEALKYGAPPHGGLAFGLDRVVALMLGLDSIRDTIAFPKTQRG 578
Query: 436 LVP 438
+ P
Sbjct: 579 ICP 581
>emb|CAA10904.1| (AJ222644) asparaginyl-tRNA synthetase [Arabidopsis thaliana]
Length = 566
Score = 171 bits (428), Expect = 2e-41
Identities = 128/460 (27%), Positives = 215/460 (45%), Gaps = 52/460 (11%)
Query: 16 GKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIP-KLNSEDVIVV 74
G+ + + GWV+ ++ + FI I D + + + ++ + + + V
Sbjct: 108 GQSLNIMGWVRTLRSQSSVTFIEINDGSCLSNLQCVMTSDAEGYDQVESGSILTGASVSV 167
Query: 75 EGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPRVM 134
+G + + K E+ EK+ V+ + + P+ + L T+ R R
Sbjct: 168 QGTIVASQGTKQKVELKVEKIIVVGECDSSYPIQKKRVSREFLRTKAHLR---PRTNTFG 224
Query: 135 SIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLK--------------- 179
++ ++R+++ AT +FF + GF+ + +P I A+ EG E F +
Sbjct: 225 AVARVRNTLAYATHKFFQESGFVWVASPIITASDCEGAGEQFCVTTLIPSSHEYTDTSID 284
Query: 180 ---------------YFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHL 224
+F AFL S QL + +T L V+ GP FRAE NT+RHL
Sbjct: 285 AIPKTKGGLIDWSQDFFGKPAFLTVSGQLNGETY-ATALSDVYTFGPTFRAENSNTSRHL 343
Query: 225 NEAWSIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNE--------- 275
E W I+ E+AF + +++ M + YV+ YV +N +++++ + + +
Sbjct: 344 AEFWMIEPELAFADLDDD-MACATAYLQYVVKYVLDNCKEDMEFFDTWIEKGIIRRLSDV 402
Query: 276 PKKPFPRITYDEALEILSDLGKE----IPWGEDIDTEGEKLLGKYMLENEGAELYFIYRY 331
+K F ++ Y +A+EIL K+ + WG D+ +E E+ + + E G I Y
Sbjct: 403 AEKEFLQLGYTDAIEILLKANKKFDFPVKWGLDLQSEHERYITE---EAFGGRPVIIRDY 459
Query: 332 PSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPESFEF 391
P E K FY+ + +D V L R E+ G QRE R ++L ++ E LN ES+ +
Sbjct: 460 PKEIKAFYMRENDDGKTVAAMDMLVPRIGELIGGSQREERLEVLEARLDELKLNKESYWW 519
Query: 392 YLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPR 431
YL YG PH GFGLG ERL+ + I NIR+VI FPR
Sbjct: 520 YLDLRRYGSVPHAGFGLGFERLVQFVTGIDNIRDVIPFPR 559
>sp|O51128|SYN_BORBU ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRNA LIGASE) (ASNRS)
>gi|7437580|pir||E70112 asparagine--tRNA ligase (EC
6.1.1.22) asnS - Lyme disease spirochete
>gi|2687998|gb|AAC66501.1| (AE001123) asparaginyl-tRNA
synthetase (asnS) [Borrelia burgdorferi]
Length = 466
Score = 168 bits (420), Expect = 2e-40
Identities = 130/452 (28%), Positives = 205/452 (44%), Gaps = 43/452 (9%)
Query: 19 VKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF-KLIPKLNSEDVIVVEGI 77
V + GW++ + G I FI I D + + A + + K + KL + I + G+
Sbjct: 22 VTINGWIRTKRSNGKIGFIEINDGSTLKGIQAVINEEENQFSEKDLKKLTTGTSISLTGL 81
Query: 78 VNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPRVMSIF 137
+ +P +EI VI + T P K + + + + +R +I
Sbjct: 82 LVESPAKGQNYEIKTHSFNVIGE--TDPETYPLQKKRHSFEFLREIPHLRIRTNTFGAIA 139
Query: 138 KIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLK------------------ 179
++R+ + E+F K GF I+TP I + EG E+F +
Sbjct: 140 RVRNKISYKIHEYFQKNGFFYINTPIITSNDGEGAGEMFRVSTLKFNKLNNALSNIDFKD 199
Query: 180 -YFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIE 238
+F +AFL+ + QL+ + + L K++ GP FRAE NTTRH +E W I+ EMAF +
Sbjct: 200 DFFGKEAFLSVTGQLHGEAY-AMALSKIYTFGPTFRAENSNTTRHASEFWMIEPEMAFYK 258
Query: 239 SEEEVMDLLERLILYVINYVRENNEKELKILEFEL---------NEPKKPFPRITYDEAL 289
+ + L E L+ Y+++ + +++ LE + N F ITY +A+
Sbjct: 259 LNDNIA-LAEDLLKYLLSSILNECSQDMDFLENYIEKGLIKKLENVINSNFEVITYTKAI 317
Query: 290 EILSDLGKEIP----WGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYED 345
EIL + K WG D+ T+ E+ Y+ E + + YP K FY+ +D
Sbjct: 318 EILENSKKNFEIKPYWGIDLQTDHER----YLTEETFKKPVVVIDYPKNFKAFYMKANKD 373
Query: 346 KPEVCKAFDLEYRGV-EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHG 404
V K D+ + EI G +RE L +I+E LN E +YL +G PH
Sbjct: 374 NKTV-KGMDILVPKIGEIIGGSEREDDLQKLENRIKELNLNIEHLNWYLDLRRFGSAPHS 432
Query: 405 GFGLGAERLIMRMLDIGNIREVILFPRDRRRL 436
GFGLG ERL+ I NIR+ I FPR + L
Sbjct: 433 GFGLGLERLVQYSTGISNIRDSIPFPRTPKNL 464
>pir||F82540 asparaginyl-tRNA synthetase XF2563 [imported] - Xylella fastidiosa
(strain 9a5c) >gi|9107777|gb|AAF85360.1|AE004064_2
(AE004064) asparaginyl-tRNA synthetase [Xylella
fastidiosa]
Length = 466
Score = 166 bits (415), Expect = 6e-40
Identities = 128/455 (28%), Positives = 211/455 (46%), Gaps = 51/455 (11%)
Query: 16 GKKVKVAGWVQEVKDL-GGIKFIWIRDRE--GIVQVTAPKKKVPQEIFKLIPKLNSEDVI 72
G +V V GWV+ +D G+ F+ + D +QV P E + KL + +
Sbjct: 17 GSEVTVRGWVRTRRDSKAGLSFVSVSDGSCFAAIQVVTPAHLPNYETE--VRKLTTGCAV 74
Query: 73 VVEGIVNFTPKAKLGFEIIPEKLEVISKAKTP--LPLDPTGKVKAELDTRLDNRFMDLRN 130
+V G + + FEI + +EV+ + P P+ P + L+ + + R
Sbjct: 75 IVIGTLAPSLGQGQQFEIQAQSIEVVGWVEDPETYPIQPK---QHSLEFLREVAHLRPRT 131
Query: 131 PRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLK----------- 179
++ +IR + +A FF++ G+ I TP I + EG ++F +
Sbjct: 132 NLFGAVARIRHCLSQAVHRFFHENGYYWITTPIITTSDAEGAGQMFRVSTLDLVNLPRTE 191
Query: 180 ---------YFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSI 230
+F + FL S QL + + L KV+ GP FRAE +T RHL E W I
Sbjct: 192 TGGIDFSHDFFGKETFLTVSGQLNVEAY-ALALSKVYTFGPTFRAENSHTPRHLAEFWMI 250
Query: 231 DAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEP---------KKPFP 281
+ E+AF + E+ + E+ + ++ V E +L + + + K PF
Sbjct: 251 EPEIAFADLAEDAR-VAEQFLKFLFKTVLEERTDDLAFITERVEKTTISKLEGFIKSPFE 309
Query: 282 RITYDEALEILSDLGKE----IPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKP 337
RI Y +A+++L GK+ + WG D+ TE E+ ++ E + YP K
Sbjct: 310 RIEYTDAIKLLERSGKKFDFPVEWGLDLQTEHER----WLTEKHIGRPVVVTNYPEHIKA 365
Query: 338 FYIMKYEDKPEVCKAFDLEYRGV-EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAF 396
FY M+ D + A D+ G+ EI G QRE R ++L ++ + GL+P +++Y
Sbjct: 366 FY-MRLNDDGKTVAAMDVLAPGIGEIIGGSQREERLEMLDIRMAQFGLDPTHYQWYRDFR 424
Query: 397 EYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPR 431
YG PH GFGLG ERL++ + + NIR+ I +PR
Sbjct: 425 RYGSVPHAGFGLGFERLMVYVCGLSNIRDAIPYPR 459
>sp|O32038|SYD_BACSU ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|7437581|pir||D69591 aspartate--tRNA ligase (EC
6.1.1.12) aspS - Bacillus subtilis
>gi|2635219|emb|CAB14714.1| (Z99118) aspartyl-tRNA
synthetase [Bacillus subtilis]
Length = 592
Score = 160 bits (401), Expect = 3e-38
Identities = 104/296 (35%), Positives = 165/296 (55%), Gaps = 25/296 (8%)
Query: 3 RTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKL 62
RT+Y +ITE+ G+ V + GWVQ+ +DLGG+ FI +RDR GIVQV V +E +
Sbjct: 4 RTYYCGDITEKAIGESVTLKGWVQKRRDLGGLIFIDLRDRTGIVQVVF-NPDVSKEALAI 62
Query: 63 IPKLNSEDVIVVEGIV------NFTPKAKLG-FEIIPEKLEVISKAKTPLPLDPTGKVKA 115
+ +E V+ ++G V P K G EI + + V++ AKTP +
Sbjct: 63 AEGIRNEYVLDIQGKVVAREEGTVNPNLKTGAIEIHADGVNVLNAAKTPPFAISDQAEEV 122
Query: 116 ELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTE- 174
D RL +R++DLR P + ++R +V +A R F + GF++I TP + + EG +
Sbjct: 123 SEDVRLKHRYLDLRRPAMFQTMQLRHNVTKAVRSFLDENGFLDIETPILTGSTPEGARDY 182
Query: 175 LFPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAE 233
L P + E + + L QSPQL+KQ++M +G+++ ++I FR E+ R E ID E
Sbjct: 183 LVPSRVHEGEFYALPQSPQLFKQLLMVSGIERYYQIARCFRDEDLRADRQ-PEFTQIDIE 241
Query: 234 MAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEAL 289
M+F+ S+E++M L E ++ V +RE +EL++ P PR+TYDEA+
Sbjct: 242 MSFM-SQEDIMSLAEEMMAKV---MRETKGEELQL----------PLPRMTYDEAM 283
>sp|P56459|SYD_HELPY ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|7437582|pir||A64597 aspartate--tRNA ligase (EC
6.1.1.12) - Helicobacter pylori (strain 26695)
>gi|2313739|gb|AAD07682.1| (AE000576) aspartyl-tRNA
synthetase (aspS) [Helicobacter pylori 26695]
Length = 577
Score = 159 bits (397), Expect = 8e-38
Identities = 111/299 (37%), Positives = 164/299 (54%), Gaps = 32/299 (10%)
Query: 2 LRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTA-PKKKVPQEIF 60
+R+H+ +EI+E+ GK VKVAGW +D GG+ FI +RD+ G+VQ+ P K ++
Sbjct: 1 MRSHFCTEISEKDVGKIVKVAGWCNTYRDHGGVVFIDLRDKSGLVQLVCDPSSKAYEKAL 60
Query: 61 KLIPKLNSEDVIVVEGIVNF------TPKAKLG-FEIIPEKLEVISKAKTPLPLDPTGKV 113
++ SE V+V +G V PK K G EI+ E+L + +K+ TP P++ G
Sbjct: 61 EV----RSEFVLVAKGKVRLRGAGLENPKLKTGKIEIVLEELIIENKSATP-PIE-IGNK 114
Query: 114 KAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGT 173
D RL R++DLR+P IFK+RS V TR ++GF+EI TP + T EG
Sbjct: 115 HVNEDLRLKYRYLDLRSPNSYEIFKLRSEVALITRNTLAQKGFLEIETPILSKTTPEGAR 174
Query: 174 E-LFPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSID 231
+ L P + E + F L QSPQL+KQ++M G+D+ F+I FR E+ R E ID
Sbjct: 175 DYLVPSRVHEGEFFALPQSPQLFKQLLMVGGMDRYFQIARCFRDEDLRADRQ-PEFTQID 233
Query: 232 AEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALE 290
AEM+F + E +VM ++E L+ + V + KPF R+ Y EA+E
Sbjct: 234 AEMSFCD-ENDVMGVVEDLLQEIFKAVG--------------HTISKPFKRMPYKEAME 277
>sp|P57441|SYN_BUCAI ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRNA LIGASE) (ASNRS)
>gi|10039030|dbj|BAB13064.1| (AP001119) asparaginyl-tRNA
synthetase [Buchnera sp. APS]
Length = 466
Score = 157 bits (394), Expect = 2e-37
Identities = 130/448 (29%), Positives = 197/448 (43%), Gaps = 43/448 (9%)
Query: 19 VKVAGWVQEVKDL-GGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVEGI 77
+ V GWV+ + G FI I D + +K I L + +++ G
Sbjct: 20 ITVCGWVRNRRSSKSGFSFITIYDGSCFNSIQVIANNTLPNYYKEILHLTTGCSVMLSGK 79
Query: 78 VNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPRVMSIF 137
+ + K +EI +K++V+ + P P K + + + R + +I
Sbjct: 80 LILSIGDKQKYEIQLKKIKVLGWVENPETY-PISSKKHSTEYLREVAHLRSRTNLIGAIA 138
Query: 138 KIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLK------------------ 179
+IR+ + + FFYKE + + TP I + TEG E+F +
Sbjct: 139 RIRNYILHSLHHFFYKEKYYWVPTPIITSLNTEGAGEMFRVSTLDMENIPKNLDSSVDFK 198
Query: 180 --YFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFI 237
+F ++FL S QL + + L KV+ GP FRAE NT RHL E W ++ E AF
Sbjct: 199 KDFFGKESFLTVSGQLNLETY-ACSLSKVYTFGPTFRAENSNTGRHLAEFWMLEVESAFT 257
Query: 238 ESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEP---------KKPFPRITYDEA 288
+ + + D E ++ YV + + ++ LE N F RI Y E
Sbjct: 258 DLND-ISDFAECMLKYVCKSLLKKCITDINFLENYTNSNIVDRLEKFLLVDFVRIDYVEV 316
Query: 289 LEILSD----LGKEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYE 344
+ IL D + G D+ +E E+ +++EN + YP E K FY+
Sbjct: 317 INILLDSKIKFNNSVFLGIDLSSEHER----FLVENYFKIPVIVKNYPKELKAFYMRLNN 372
Query: 345 DKPEVCKAFDLEYRGV-EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPH 403
DK V A D+ V E+ G QRE R IL E++ E GL E + +Y YG PH
Sbjct: 373 DKKTVA-AIDILVPNVGELIGGSQREERIAILDERLLELGLKKEDYWWYRDLRRYGTVPH 431
Query: 404 GGFGLGAERLIMRMLDIGNIREVILFPR 431
GFG+G ERLI I NIR++I FPR
Sbjct: 432 SGFGMGFERLISYFTGITNIRDLIPFPR 459
>sp|Q9X1F4|SYD_THEMA ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|7437606|pir||F72252 aspartate--tRNA ligase (EC
6.1.1.12) - Thermotoga maritima (strain MSB8)
>gi|4982006|gb|AAD36510.1|AE001796_2 (AE001796)
aspartyl-tRNA synthetase [Thermotoga maritima]
Length = 579
Score = 157 bits (393), Expect = 2e-37
Identities = 104/303 (34%), Positives = 166/303 (54%), Gaps = 38/303 (12%)
Query: 1 MLRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF 60
MLRTH E+ GKKVK+ GWV ++DLGG++FI +RDR G Q+ V E +
Sbjct: 1 MLRTHTCGELRATDEGKKVKLCGWVDRIRDLGGVRFIDLRDRYGETQIVC---DVNSEAY 57
Query: 61 KLIPKLNSEDVIVVEGIVNFTPKAKLG-------FEIIPEKLEVISKAKTPLPLDPTGKV 113
++ +L E V++VEG V P+ E++ E++E++S A PLP P
Sbjct: 58 SVVDELTRESVVLVEGTVRKRPEGTENPNIETGEIEVVAERIEILSLA-DPLPFYPGETP 116
Query: 114 KAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGG- 172
K E+ RL R++DLR+ R+ +R + + R++F + GF+EI TP + + EG
Sbjct: 117 KEEM--RLKYRYIDLRSERMKRNIILRYRISKIIRDYFDELGFLEIETPFLTRSTPEGAR 174
Query: 173 -----TELFPLKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEA 227
+ L P K++ L QSPQL+KQ++M +G D+ F+I FR E+ R E
Sbjct: 175 DFLVPSRLRPGKFYA----LPQSPQLFKQILMISGFDRYFQIVRCFRDEDLRADRQ-PEF 229
Query: 228 WSIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDE 287
+D EM+F++ E+V+++ E ++ V +E++ +LK+ PF RI YD+
Sbjct: 230 TQVDVEMSFVD-VEDVLNVSEGMVSRVF---KESSGIDLKV----------PFDRIPYDD 275
Query: 288 ALE 290
A+E
Sbjct: 276 AME 278
Score = 71.8 bits (173), Expect = 1e-11
Identities = 42/110 (38%), Positives = 57/110 (51%), Gaps = 5/110 (4%)
Query: 327 FIYRYPSEAKPFYIMKYEDKPEV-CKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLN 385
F+ R+ P +D +V KA+DL G E+ G R HR DI + GL+
Sbjct: 440 FVARHHPFTMPVLETLGDDYTKVRAKAYDLVINGYEVGGGSIRIHRRDIQEKIFELLGLS 499
Query: 386 PES----FEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPR 431
E F F+L AF YG+PPHGG G +RL+ + +IREVI FP+
Sbjct: 500 EEEAQKKFGFFLEAFRYGVPPHGGIAFGLDRLVSIIAGESSIREVIAFPK 549
>sp|Q9ZLL9|SYD_HELPJ ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|7437600|pir||C71916 aspartate--tRNA ligase (EC
6.1.1.12) - Helicobacter pylori (strain J99)
>gi|4155111|gb|AAD06143.1| (AE001489) ASPARTYL-TRNA
SYNTHETASE [Helicobacter pylori J99]
Length = 579
Score = 155 bits (389), Expect = 7e-37
Identities = 108/299 (36%), Positives = 163/299 (54%), Gaps = 32/299 (10%)
Query: 2 LRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQ-VTAPKKKVPQEIF 60
+R+H+ +EI+E+ GK +KVAGW +D GG+ FI +RD+ G+VQ V P K ++
Sbjct: 1 MRSHFCTEISEKDVGKTIKVAGWCNTYRDHGGVVFIDLRDKSGLVQLVCDPSSKAYEKAL 60
Query: 61 KLIPKLNSEDVIVVEGIVNF------TPKAKLG-FEIIPEKLEVISKAKTPLPLDPTGKV 113
++ SE V+V +G PK K G EI+ E+L + +K+ TP P++ G
Sbjct: 61 ----EVRSEFVLVAKGKARLRGAGLENPKLKTGKIEIVLEELVIENKSATP-PIE-IGNK 114
Query: 114 KAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGT 173
D RL R++DLR+ IFK+RS V TR ++GF+EI TP + T EG
Sbjct: 115 SVNEDLRLKYRYLDLRSLNAYEIFKLRSEVALITRNALAQKGFLEIETPILSKTTPEGAR 174
Query: 174 E-LFPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSID 231
+ L P + E + F L QSPQL+KQ++M G+D+ F+I FR E+ R E ID
Sbjct: 175 DYLVPSRVHEGEFFALPQSPQLFKQLLMVGGMDRYFQIARCFRDEDLRADRQ-PEFTQID 233
Query: 232 AEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALE 290
AEM+F + E++VM ++E L+ + + + KPF R+ Y EA+E
Sbjct: 234 AEMSFCD-EDDVMGVVEDLLQEIFKAIG--------------HTISKPFKRMPYKEAME 277
Score = 69.1 bits (166), Expect = 1e-10
Identities = 40/112 (35%), Positives = 61/112 (53%), Gaps = 8/112 (7%)
Query: 331 YPSEAKPFYIMKY---EDKPEV-CKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNP 386
Y + PF + K ED E+ A+D+ GVE+ G R H+ ++ + + +N
Sbjct: 440 YHAAHHPFTMPKNIECEDIEEIEAHAYDVVLNGVELGGGSIRIHKEEMQKKVFEKININE 499
Query: 387 ES----FEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRR 434
E F F L A ++G PPHGGF +G +RLIM M +IR+VI FP+ ++
Sbjct: 500 EEAQKKFGFLLEALKFGAPPHGGFAIGFDRLIMLMTKSNSIRDVIAFPKTQK 551
>sp|P36419|SYD_THETH ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|420805|pir||S33743 aspartate--tRNA ligase (EC
6.1.1.12) - Thermus aquaticus >gi|9257069|pdb|1EFW|A
Chain A, Crystal Structure Of Aspartyl-Trna Synthetase
From Thermus Thermophilus Complexed To Trnaasp From
Escherichia Coli >gi|9257070|pdb|1EFW|B Chain B, Crystal
Structure Of Aspartyl-Trna Synthetase From Thermus
Thermophilus Complexed To Trnaasp From Escherichia Coli
>gi|396501|emb|CAA50282.1| (X70943) aspartyl-tRNA
synthetase [Thermus thermophilus]
Length = 580
Score = 153 bits (383), Expect = 3e-36
Identities = 106/321 (33%), Positives = 170/321 (52%), Gaps = 30/321 (9%)
Query: 1 MLRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF 60
M RTHY+ + E G++V + GWV +DLGG+ F+ +RDREG+VQ+ A +
Sbjct: 1 MRRTHYAGSLRETHVGEEVVLEGWVNRRRDLGGLIFLDLRDREGLVQLVA---HPASPAY 57
Query: 61 KLIPKLNSEDVIVVEGIVNFTPK-----AKLGFEIIPEKLEVISKAKT-PLPLDPTGKVK 114
++ E V+ +G+V P+ A E+ LEV+++AKT P P+D + +
Sbjct: 58 ATAERVRPEWVVRAKGLVRLRPEPNPRLATGRVEVELSALEVLAEAKTPPFPVDAGWRGE 117
Query: 115 AELDT----RLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATE 170
E + RL R++DLR R+ ++R V +A +F +EGF+++ TP + + E
Sbjct: 118 EEKEASEELRLKYRYLDLRRRRMQENLRLRHRVIKAIWDFLDREGFVQVETPFLTKSTPE 177
Query: 171 GGTELFPLKYFENDAF--LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAW 228
G + E F L QSPQL+KQM+M GLD+ F+I FR E+ R +
Sbjct: 178 GARDFLVPYRHEPGLFYALPQSPQLFKQMLMVAGLDRYFQIARCFRDEDLRADRQ-PDFT 236
Query: 229 SIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEA 288
+D EM+F+E E+V++L ERL+ +V RE EL + PFPR++Y+EA
Sbjct: 237 QLDLEMSFVE-VEDVLELNERLMAHVF---REALGVELPL----------PFPRLSYEEA 282
Query: 289 LEILSDLGKEIPWGEDIDTEG 309
+E ++ +G ++ G
Sbjct: 283 MERYGSDKPDLRFGLELKEVG 303
>sp|O83618|SYN_TREPA ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRNA LIGASE) (ASNRS)
>gi|7437574|pir||F71302 asparagine--tRNA ligase (EC
6.1.1.22) (asnS) - syphilis spirochete
>gi|3322907|gb|AAC65585.1| (AE001236) asparaginyl-tRNA
synthetase (asnS) [Treponema pallidum]
Length = 523
Score = 151 bits (378), Expect = 1e-35
Identities = 127/516 (24%), Positives = 217/516 (41%), Gaps = 99/516 (19%)
Query: 10 ITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDRE--GIVQVTAP-------------KKK 54
+T +G+ V GWV+ ++ FI + D +QVT P ++
Sbjct: 12 LTHPPSGQHECVHGWVRSKRETKRAVFISLSDGSCPDTLQVTVPLPECSASLSSGAQAEQ 71
Query: 55 VP---------QEIFKLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPL 105
+P + + + + ++ + I EG + +P A E+ L V+ +A P
Sbjct: 72 IPNVRDAVLQGETLAQTLKRVTTGACIRAEGALVPSPGAGQALELRACNLTVLGEA--PA 129
Query: 106 PLDPTGKVKAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKII 165
P K + + + R + ++RS++ A FF + F +HTP I
Sbjct: 130 ETYPLQKKSHSFEFLRAHAHLRARTSTFAACARVRSALAGAVHRFFSERHFQYVHTPIIT 189
Query: 166 ATATEGGTELFPLKYFEN----------------------DAFLAQSPQLYKQMMM---- 199
A+ EG ELF + F+ D F ++ +L +
Sbjct: 190 ASDCEGAGELFRVTTFDPVRIAREAHAAGAAGNPYALTYADDFFGKAARLTVSGQLQGEA 249
Query: 200 -STGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYVINYV 258
+ L +++ GP FRAE NT+RHL+E W ++ E+AF + MD+ E + Y++
Sbjct: 250 YALALTRIYTFGPTFRAENSNTSRHLSEFWMVEPEIAFARITD-CMDVAEEFLAYLLRAA 308
Query: 259 RENNEKELKILEFELNE-----------------------------------PKKPFPRI 283
++ +++ L+ + + P R+
Sbjct: 309 LKDCAQDIAFLDERAAQHARSARGDTPLAARSTARTPPVRTPGQLTRMLEDVARAPATRL 368
Query: 284 TYDEALEILSDLGKE----IPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFY 339
TY EA+++L + G+ + WG D+ +E E L + + +Y YP E K FY
Sbjct: 369 TYTEAIKLLENSGRSFEFPVRWGCDLQSEHECFLTEEVFHGP----VIVYDYPKEIKAFY 424
Query: 340 IMKYEDKPEVCKAFDLEYRGV-EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEY 398
MK ++ DL G+ EI G +RE + ++L +IR G +P + +Y +
Sbjct: 425 -MKLNADGTTVRSMDLLVPGLGEIMGGSEREEQFEVLCARIRASGFDPHDYRWYTDLRRF 483
Query: 399 GMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRR 434
G PH GFGLG ERL+ + +GNIR+VI FPR R
Sbjct: 484 GTAPHAGFGLGFERLLQYVTGLGNIRDVIPFPRTPR 519
>pir||H82627 aspartyl-tRNA synthetase XF1856 [imported] - Xylella fastidiosa
(strain 9a5c) >gi|9106945|gb|AAF84662.1|AE004007_1
(AE004007) aspartyl-tRNA synthetase [Xylella fastidiosa]
Length = 589
Score = 150 bits (376), Expect = 2e-35
Identities = 106/298 (35%), Positives = 156/298 (51%), Gaps = 28/298 (9%)
Query: 2 LRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQ---E 58
+RTH+ I E L G V +AGW ++LGG+ FI +RD EGIVQVT + + Q E
Sbjct: 1 MRTHFCGLIDETLIGHTVTLAGWTDVARNLGGVCFIDLRDHEGIVQVTVDSRAIDQNNSE 60
Query: 59 IFKLIPKLNSEDVIVVEGIV----NFTPKAKLG-FEIIPEKLEVISKAKTPLPLDPTGKV 113
+FK+ L+ EDV+ VEG+V K K G E+I K+++++KA PLP
Sbjct: 61 LFKVASGLSYEDVLQVEGVVCARHAVNDKIKTGKVEVIATKIKILNKA-APLPFH--AHE 117
Query: 114 KAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGT 173
D RL R++DLR P + + + R + +A R GF +I TP + EG
Sbjct: 118 NPGEDIRLKYRYLDLRRPEMQRMQRTRIKLVQALRRHLDMHGFQDIETPILTKATPEGAR 177
Query: 174 E-LFPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSID 231
+ L P + + + L QSPQL+KQ++M G D+ ++I FR E R L E +D
Sbjct: 178 DFLVPARMHPGEFYALPQSPQLFKQILMVAGFDRYYQIARCFRDEALRADRQL-EFTQLD 236
Query: 232 AEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEAL 289
E AF+ SE +V D +E +I V KE+ +E + FPR+T+ EA+
Sbjct: 237 MEFAFV-SERDVQDFVEEMIRRVF--------KEVAGIELDTT-----FPRMTWTEAM 280
>pir||H71612 asparagine--tRNA ligase (EC 6.1.1.22) (OO, TP) PFB0525w - malaria
parasite (Plasmodium falciparum)
>gi|3845207|gb|AAC71894.1| (AE001400) asparaginyl-tRNA
synthetase (OO, TP) [Plasmodium falciparum]
Length = 610
Score = 150 bits (376), Expect = 2e-35
Identities = 93/265 (35%), Positives = 140/265 (52%), Gaps = 19/265 (7%)
Query: 180 YFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIES 239
+F AFL S QL + + S+ + V+ GP FRAE +T+RHL E W I+ E+AF +
Sbjct: 345 FFSKQAFLTVSGQLSLENLCSS-MGDVYTFGPTFRAENSHTSRHLAEFWMIEPEIAFADL 403
Query: 240 EEEVMDLLERLILYVINYVRENNEKELKILEFEL---------NEPKKPFPRITYDEALE 290
+ M+L E I Y I+YV NN ++ E + N + F +ITY A+E
Sbjct: 404 YDN-MELAEAYIKYCIDYVLNNNFHDIYYFEENVETNLIKRLKNILNEDFAKITYTNAIE 462
Query: 291 ILSDLGK----EIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDK 346
IL + ++ WG D+ +E E+ + + + + +Y YP + K FY+ ED
Sbjct: 463 ILQNYSDSFEVKVEWGMDLQSEHERFIAEKIFKKP----VIVYNYPKDLKAFYMKLNEDN 518
Query: 347 PEVCKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGF 406
V L + E+ G QRE + L + I+EK LN +S+ +Y + +YG PH GF
Sbjct: 519 KTVAAMDVLVPKIGEVIGGSQREDNLERLDKMIKEKKLNIDSYWWYRQLRQYGSHPHAGF 578
Query: 407 GLGAERLIMRMLDIGNIREVILFPR 431
GLG ERLIM + + NI++ I FPR
Sbjct: 579 GLGFERLIMLVTGVDNIKDTIPFPR 603
>gb|AAD46681.1|AF170909_1 (AF170909) SYNC1 protein [Arabidopsis thaliana]
>gi|10176772|dbj|BAB09886.1| (AB013392) SYNC1 protein
[Arabidopsis thaliana]
Length = 572
Score = 148 bits (370), Expect = 1e-34
Identities = 91/268 (33%), Positives = 142/268 (52%), Gaps = 22/268 (8%)
Query: 180 YFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIES 239
+F AFL S QL + + L V+ GP FRAE +T+RHL E W ++ E+AF +
Sbjct: 304 FFGRQAFLTVSGQLQVETY-ACALSNVYTFGPTFRAENSHTSRHLAEFWMVEPEIAFADL 362
Query: 240 EEEVMDLLERLILYVINYVRENNEKELKILEFELNE---------PKKPFPRITYDEALE 290
E++ M+ E + Y+ N++ E +++++ + PF RITY +A+E
Sbjct: 363 EDD-MNCAEAYVKYMCNWLLEKCYADMELMAKNFDSGCIDRLKLVASTPFGRITYTKAIE 421
Query: 291 ILSDL---GKE----IPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKY 343
+L + GKE + WG D+ +E E+ L + + + +Y YP K FY+
Sbjct: 422 LLEEAVAKGKEFDNNVEWGIDLASEHERYLTEVLFQKP----LIVYNYPKGIKAFYMRLN 477
Query: 344 EDKPEVCKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPH 403
+D+ V L + E+ G QRE R+D++ ++I E GL E +E+YL YG H
Sbjct: 478 DDEKTVAAMDVLVPKVGELIGGSQREERYDVIKKRIEEMGLPIEPYEWYLDLRRYGTVKH 537
Query: 404 GGFGLGAERLIMRMLDIGNIREVILFPR 431
GFGLG ER+I+ + NIR+VI FPR
Sbjct: 538 CGFGLGFERMILFATGLDNIRDVIPFPR 565
>pir||E83524 aspartyl-tRNA synthetase PA0963 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9946870|gb|AAG04352.1|AE004530_5
(AE004530) aspartyl-tRNA synthetase [Pseudomonas
aeruginosa]
Length = 591
Score = 148 bits (369), Expect = 2e-34
Identities = 94/299 (31%), Positives = 161/299 (53%), Gaps = 30/299 (10%)
Query: 1 MLRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF 60
M+R+HY ++ E L+G++V + GWV +D GG+ F+ +RDREG+ QV + E F
Sbjct: 1 MMRSHYCGQLNESLDGQEVTLCGWVHRRRDHGGVIFLDVRDREGLAQVVFDPDRA--ETF 58
Query: 61 KLIPKLNSEDVIVVEGIVNFTPK-------AKLGFEIIPEKLEVISKAKT-PLPLDPTGK 112
++ SE V+ + G V P+ A E++ +LEV+++A+T P PLD
Sbjct: 59 AKADRVRSEFVVKITGKVRLRPEGARNPNMASGSIEVLGYELEVLNQAETPPFPLDEYSD 118
Query: 113 VKAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGG 172
V E TRL RF+DLR P + + K+R+ + + R + GF+++ TP + EG
Sbjct: 119 VGEE--TRLRYRFIDLRRPEMAAKLKLRARITSSIRRYLDDNGFLDVETPILGRPTPEGA 176
Query: 173 TE-LFPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSI 230
+ L P + + F L QSPQL+KQ++M G D+ ++I FR E+ R E I
Sbjct: 177 RDYLVPSRTYPGHFFALPQSPQLFKQLLMVAGFDRYYQIAKCFRDEDLRADRQ-PEFTQI 235
Query: 231 DAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEAL 289
D E +F++ E +++ + E+++ + ++L+ E +E FP + ++EA+
Sbjct: 236 DIETSFLD-ESDIIGITEKMVRQLFK----------EVLDVEFDE----FPHMPFEEAM 279
>dbj|BAB04971.1| (AP001511) aspartyl-tRNA synthetase [Bacillus halodurans]
Length = 595
Score = 146 bits (366), Expect = 3e-34
Identities = 95/296 (32%), Positives = 161/296 (54%), Gaps = 26/296 (8%)
Query: 3 RTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKL 62
RTH+ +++EE ++V++ GWVQ +DLG + F+ +RDR G+VQ+ + QE +
Sbjct: 4 RTHHCGQLSEEQVNERVQLKGWVQRRRDLGQVIFVDLRDRSGVVQLVF-NSDISQEALET 62
Query: 63 IPKLNSEDVIVVEGIV------NFTPKAKLG-FEIIPEKLEVISKAKTPLPLDPTGKVKA 115
K+ +E V+ VEG+V K G E+ E+L +++KAK+ LP A
Sbjct: 63 AEKVRNEYVLDVEGVVLKRDPSTVNDKIATGTIEVHVERLTILNKAKS-LPFQIEANTDA 121
Query: 116 ELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTE- 174
D RL R++DLR P + K+R + R+F + F EI TP + + EG +
Sbjct: 122 SEDIRLKYRYLDLRRPDMQETMKLRHQTTKLIRDFLDGQEFFEIETPMLTKSTPEGARDY 181
Query: 175 LFPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAE 233
L P + + + L QSPQ++KQ++M +G ++ ++I FR E+ R E ID E
Sbjct: 182 LVPSRVHHGEFYALPQSPQIFKQLLMVSGFERYYQIVRCFRDEDLRADRQ-PEFTQIDIE 240
Query: 234 MAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEAL 289
+F++ +E+++ + E ++ ++ KE+K L+ L PFPR+TYD+A+
Sbjct: 241 TSFMD-KEDLLTMTENMMAKIM--------KEVKGLDVAL-----PFPRMTYDDAM 282
>sp|P41255|SYK_THETH LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|1072959|pir||A55589 lysine--tRNA ligase (EC 6.1.1.6)
- Thermus aquaticus >gi|486665|emb|CAA50039.1| (X70708)
lysine--tRNA ligase [Thermus thermophilus]
Length = 492
Score = 146 bits (365), Expect = 4e-34
Identities = 132/447 (29%), Positives = 221/447 (48%), Gaps = 52/447 (11%)
Query: 17 KKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVEG 76
++V VAG + ++ +G + F + D G +Q+ + P+ ++L+ KL+ D++ V G
Sbjct: 52 EEVAVAGRLVALRRMGKVTFAHLLDETGRIQLYFQRDLTPK--YELLKKLDVGDILGVRG 109
Query: 77 IVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLR-NPRVMS 135
FT K E+ + L+ K+ PL + + R R++DL NP V
Sbjct: 110 HP-FTTKTG---EVTVKVLDWTPLVKSLHPLPDKWHGLRDKEVRYRQRYLDLIVNPEVRE 165
Query: 136 IFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFEN----DAFLAQSP 191
+F+ RS + R R FF +GF+E+ TP I T GG E P K + N + +L S
Sbjct: 166 VFRRRSEIVRYIRRFFEAKGFLEVETP--ILQPTTGGAEARPFKTYHNALDHEFYLRISL 223
Query: 192 QLYKQMMMSTGLDKVFEIGPIFRAE--EHNTTRHLNEAWSIDAEMAFIESEEEVMDLLER 249
+LY + ++ G +KVFEIG FR E +HN H E ++A A+ + ++ + L+E
Sbjct: 224 ELYLKRLLVGGYEKVFEIGRNFRNEGIDHN---HNPEFTMLEAYWAYADYQD-MAGLVEE 279
Query: 250 LILYVINYVRENNEKEL--KILEFELNEPKKPFPRITYDEALEILS-------DLGKEIP 300
L+ ++ ++ ++E ++L F K PF RI++ EAL+ + DL +
Sbjct: 280 LLSGLVLHLFGSHEVPYQGRVLNF-----KPPFRRISFVEALKEKAGLPFDPLDLERLRL 334
Query: 301 WGEDIDTEG---------EKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCK 351
W + E +KL G Y+ E E + F++ +P P ++ +KP + +
Sbjct: 335 WADAHHPELSQVPNYKLLDKLFGIYV-EPELQDPTFVFDFPLAISPL-AKRHREKPGLVE 392
Query: 352 AFDLEYRGVEISS-----GGQREHRHDILVEQIREKGLN---PESFEFYLRAFEYGMPPH 403
+DL G+E++ + R L + R K + PE E +L A EYGMPP
Sbjct: 393 RWDLYAGGMELAPCYSELNDPLDQRERFLEQARRRKEGDEEAPEPDEDFLLALEYGMPPA 452
Query: 404 GGFGLGAERLIMRMLDIGNIREVILFP 430
G GLG +RL M + D ++R+V+LFP
Sbjct: 453 AGLGLGIDRLAMLLTDQPSLRDVLLFP 479
>pir||D82910 aspartyl-tRNA synthetase UU286 [imported] - Ureaplasma urealyticum
>gi|6899259|gb|AAF30695.1|AE002125_6 (AE002125)
aspartyl-tRNA synthetase [Ureaplasma urealyticum]
Length = 578
Score = 143 bits (358), Expect = 3e-33
Identities = 102/300 (34%), Positives = 157/300 (52%), Gaps = 27/300 (9%)
Query: 6 YSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPK 65
Y I EE K V + GWV++V+ +G + F+ ++DR GIVQ+ A K +F + +
Sbjct: 4 YCGYIGEEHLEKNVILNGWVKKVRKMGNLVFVDLKDRFGIVQIFATKS---DGVFNELTQ 60
Query: 66 LNSEDVIVVEGIV----NFTPKAKLG-FEIIPEKLEVISKAKTPLPLDPTGKVKAELDTR 120
L+ EDVI VEG+V N K G FEI +K+ + SKAKTP PL + A + R
Sbjct: 61 LSREDVINVEGLVLLRKNPNNDLKTGRFEIHVKKILIYSKAKTP-PLIIEDETDANEEIR 119
Query: 121 LDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKY 180
R++DLR + IF++RS V++A R + Y + FIE TP + EG + +
Sbjct: 120 FRYRYLDLRRDVNLKIFELRSKVYQAFRNYLYSQDFIETETPILAKPTPEGARDFYVPTR 179
Query: 181 FENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESE 240
L QSPQ +KQ++M G K F+I FR E+ + R E +D E++F + E
Sbjct: 180 TRKFYALPQSPQTFKQLLMVAGFQKYFQITKCFRDEDLRSDRQ-PEFTQVDIELSFAD-E 237
Query: 241 EEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIP 300
E+ L+E L+ YV + + +L PF R++Y++A ++D G + P
Sbjct: 238 IEIQTLIENLLKYVFK----------QTINVDLT---TPFMRMSYEQA---INDYGSDKP 281
>gi|6319872 Asn-tRNA synthetase; Ycr024cp [Saccharomyces cerevisiae]
>gi|135160|sp|P25345|SYNM_YEAST ASPARAGINYL-TRNA
SYNTHETASE, MITOCHONDRIAL PRECURSOR (ASPARAGINE--TRNA
LIGASE) (ASNRS) >gi|83213|pir||S19435 hypothetical
protein YCR024c - yeast (Saccharomyces cerevisiae)
>gi|1907168|emb|CAA42316.1| (X59720) YCR024c, len:492
[Saccharomyces cerevisiae]
Length = 492
Score = 142 bits (354), Expect = 9e-33
Identities = 117/461 (25%), Positives = 203/461 (43%), Gaps = 58/461 (12%)
Query: 19 VKVAGWVQEVKDLGGIKFIWIRDREGI--VQVTAPKKKVPQEIFKLIPKLNSEDVIVVEG 76
+ + GW++ ++ L I F+ ++D + +++ P + F I K + + +
Sbjct: 34 ISINGWIKSIRLLKRIAFLDLQDGTSVNPLRIVIPLTNTDEVQFLKILK-TGQTLSISNA 92
Query: 77 IVNFTPKAKLGFEII----PEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPR 132
TP K FE+ + ++++ PL + L + ++ R
Sbjct: 93 TWQSTPNRKQPFELQIKNPVKSIKLVGPVSENYPLQKKYQTLRYLRSLPTLKY---RTAY 149
Query: 133 VMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLK---------YFEN 183
+ +I ++RS V +F K F ++ P + + EG ELF + YF
Sbjct: 150 LSAILRLRSFVEFQFMLYFQKNHFTKVSPPILTSNDCEGAGELFQVSTNTSPTASSYFGK 209
Query: 184 DAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEV 243
+L S QL+ +++ + L + + + P FRAE+ +T RHL+E W ++ EM F+ S E+
Sbjct: 210 PTYLTVSTQLHLEIL-ALSLSRCWTLSPCFRAEKSDTPRHLSEFWMLEVEMCFVNSVNEL 268
Query: 244 MDLLERLILYVINYVRENNEKEL-----------KILEFELNEP------------KKPF 280
+E I ++I +N ++ L E +N+ + +
Sbjct: 269 TSFVETTIKHIIKACIDNQQELLPKQFISSQENNASSELSINQETQQIKTRWEDLINEKW 328
Query: 281 PRITYDEALEILSDLGKEI-------PWGEDIDTEGEKLL-GKYMLENEGAELYFIYRYP 332
ITY A+EIL E+ WG+ + TE EK L G+Y F+ YP
Sbjct: 329 HNITYTNAIEILKKRHNEVSHFKYEPKWGQPLQTEHEKFLAGEYF-----KSPVFVTDYP 383
Query: 333 SEAKPFYIMKYEDKPEVCKAFDLEYRGV-EISSGGQREHRHDILVEQIREKGLNPE-SFE 390
KPFY+ + + FDL G+ EI G RE +D L +++ +G+N +
Sbjct: 384 RLCKPFYMKQNSTPDDTVGCFDLLVPGMGEIIGGSLREDDYDKLCREMKARGMNRSGELD 443
Query: 391 FYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPR 431
+Y+ + G PHGGFGLG ER I + NI++ I F R
Sbjct: 444 WYVSLRKEGSAPHGGFGLGFERFISYLYGNHNIKDAIPFYR 484
>gb|AAD55509.1|AC008148_19 (AC008148) Similar to asparaginyl-tRNA synthetases [Arabidopsis
thaliana]
Length = 571
Score = 141 bits (353), Expect = 1e-32
Identities = 89/269 (33%), Positives = 140/269 (51%), Gaps = 22/269 (8%)
Query: 180 YFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIES 239
+F AFL S QL + + L V+ GP FRAE +T+RHL E W ++ E+AF +
Sbjct: 301 FFGRQAFLTVSGQLQVETY-ACALSSVYTFGPTFRAENSHTSRHLAEFWMVEPEIAFADI 359
Query: 240 EEEVMDLLERLILYVINYVRENNEKELKILEFELNE---------PKKPFPRITYDEALE 290
++ M+ E + Y+ ++ + ++++++ ++E K F R+TY EA+E
Sbjct: 360 HDD-MNCAEAYVKYMCKWLMDKCGDDMELMDKNVDEGCTKRLNMVAKASFKRVTYTEAIE 418
Query: 291 ILSDL---GK-----EIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMK 342
L GK ++ WG D+ +E E+ L + + + +Y YP K FY+
Sbjct: 419 RLEKAVAQGKVVFDNKVEWGIDLASEHERYLTEVEFDQKPI---IVYNYPKGIKAFYMRL 475
Query: 343 YEDKPEVCKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPP 402
+D+ V L + E+ G QRE R+D++ ++I E GL E +E+YL YG
Sbjct: 476 NDDEKTVAAMDVLVPKVGELIGGSQREERYDVIKQRIEEMGLPMEPYEWYLDLRRYGTVK 535
Query: 403 HGGFGLGAERLIMRMLDIGNIREVILFPR 431
H GFGLG ER+I I NIR+VI FPR
Sbjct: 536 HCGFGLGFERMIQFATGIDNIRDVIPFPR 564
>sp|P73443|SYK_SYNY3 LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|7437569|pir||S77380 lysine--tRNA ligase (EC 6.1.1.6)
- Synechocystis sp. (strain PCC 6803)
>gi|1652562|dbj|BAA17483.1| (D90906) lysyl-tRNA
synthetase [Synechocystis sp.]
Length = 510
Score = 140 bits (350), Expect = 3e-32
Identities = 135/475 (28%), Positives = 222/475 (46%), Gaps = 62/475 (13%)
Query: 4 THYSSEITEEL----NGK----KVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKV 55
TH + ++ E NG+ KV +AG + + +G + F ++D G +Q+ K+++
Sbjct: 39 THQAQDLQETYRDLSNGEEVDLKVAIAGRILARRVMGKLAFFTLQDESGTIQLYLEKQRL 98
Query: 56 PQEI------FKLIPKLNSE-DVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLD 108
+ + F L+ K+ D++ V G + T K +L + + V++K+ PLP
Sbjct: 99 TEHMPELENAFNLLKKITDVGDILGVTGTLKRTEKGELSVYV--QTYAVLTKSLLPLPDK 156
Query: 109 PTGKVKAELDTRLDNRFMDLR-NPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIAT 167
G E R R++DL NP V F+ R+ + A R + K+GFIEI TP +
Sbjct: 157 WHGLTDTE--KRYRQRYVDLIVNPTVRQTFRRRAQITAAIRRYLDKQGFIEIETP--VLQ 212
Query: 168 ATEGGTELFPLKYFENDA----FLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRH 223
GG E P N +L + +L+ + ++ G +KVFE+G IFR E +TRH
Sbjct: 213 GESGGAEARPFITHHNTLGMPLYLRIATELHLKRLVVGGFEKVFELGRIFR-NEGVSTRH 271
Query: 224 LNEAWSIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRI 283
E SI+ A+++ E +M L E L+ V + + E +L P K RI
Sbjct: 272 NPEFTSIEVYQAYVDYNE-MMALTEALVTTAAQAVLGTLKITYQGEEIDLTPPWK---RI 327
Query: 284 TYDEALEI--------LSDL----------GKEIPWGEDIDTEGEKLLGKYMLENEGAEL 325
T EA+++ +DL G +P ED + G L + + EG +
Sbjct: 328 TMHEAVQLETGIDFSQFTDLETAKQAATKAGIGVP--EDCPSLGHLLNHAFEQKVEGTLM 385
Query: 326 Y--FIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSGGQR-----EHRHDILVEQ 378
FI +P E P + KP + + F+L G E+++ + R + +
Sbjct: 386 QPTFIIDFPVEISPL-AKPHRSKPGLVERFELFVYGRELANSFSELTDPIDQRSRLEAQA 444
Query: 379 IREKGLNPESF---EFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFP 430
++ + E+ E +L A EYGMPP GG G+G +RL+M + D +IR+VI FP
Sbjct: 445 AKKAAGDLEAHSVDEDFLTALEYGMPPTGGLGIGIDRLVMLLTDSPSIRDVIAFP 499
>sp|P56126|SYK_HELPY LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|7437568|pir||F64542 lysine--tRNA ligase (EC 6.1.1.6)
- Helicobacter pylori (strain 26695)
>gi|2313270|gb|AAD07251.1| (AE000538) lysyl-tRNA
synthetase (lysS) [Helicobacter pylori 26695]
Length = 501
Score = 140 bits (350), Expect = 3e-32
Identities = 119/443 (26%), Positives = 211/443 (46%), Gaps = 43/443 (9%)
Query: 21 VAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVEGIVNF 80
+ G V+ ++ +G FI + D I+QV + ++ E L L D+++V+G
Sbjct: 60 IVGRVKLLRLMGKACFIKVEDESTILQVYVSQNELNDEFKSLKKHLEVGDIVLVKGFPFA 119
Query: 81 TPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLR-NPRVMSIFKI 139
T +L + + ++SK PLP G ++++ R R++DL NP V +FK
Sbjct: 120 TKTGELSIHAL--EFHILSKTIVPLPEKFHGL--SDIELRYRQRYLDLIVNPSVKDVFKK 175
Query: 140 RSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFEN----DAFLAQSPQLYK 195
RS + + R+FF EGF+E+ TP + GG P + N + +L +P+LY
Sbjct: 176 RSLIVSSVRKFFEMEGFLEVETPMM--HPIPGGANARPFITYHNALEVERYLRIAPELYL 233
Query: 196 QMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYVI 255
+ ++ G + VFEI FR E + + H E I+ A+ + E++++L +RL Y++
Sbjct: 234 KRLIVGGFEAVFEINRNFRNEGMDHS-HNPEFTMIEFYWAY-HTYEDLIELSKRLFDYLL 291
Query: 256 NYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIPWGED----------I 305
+ +++ +E + N+ I+Y +ALE + + K+I ED I
Sbjct: 292 KTLNLDSKIIYNDMEVDFNQTSV----ISYLDALETIGGISKDILEKEDRLLAYLLEQGI 347
Query: 306 DTEGEKLLGK-------YMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYR 358
E GK + +E++ F+ +YP E P + + P + F+L
Sbjct: 348 KVEPNLTYGKLLAEAFDHFVEHQLINPTFVTQYPIEISPL-ARRNDSNPNIADRFELFIA 406
Query: 359 GVEISSGGQREH----RHDILVEQIREKGLNPESFEF----YLRAFEYGMPPHGGFGLGA 410
G EI++G + + + Q+ EK E ++ Y+ A +GMPP G G+G
Sbjct: 407 GKEIANGFSELNDPLDQLERFKNQVAEKEKGDEEAQYMDEDYVWALAHGMPPTAGQGIGI 466
Query: 411 ERLIMRMLDIGNIREVILFPRDR 433
+RL+M + +I++VILFP R
Sbjct: 467 DRLVMLLTGAKSIKDVILFPAMR 489
>pir||D75406 aspartyl-tRNA synthetase, discriminating - Deinococcus radiodurans
(strain R1) >gi|6459100|gb|AAF10918.1|AE001981_3
(AE001981) aspartyl-tRNA synthetase, discriminating
[Deinococcus radiodurans]
Length = 577
Score = 140 bits (350), Expect = 3e-32
Identities = 94/297 (31%), Positives = 157/297 (52%), Gaps = 26/297 (8%)
Query: 1 MLRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF 60
M RT ++ + + V + GWV +DLGG+ F+ +RDR G VQV + F
Sbjct: 2 MKRTSLIGQLGQAQQQQTVTLQGWVSRRRDLGGLIFLELRDRSGTVQVQV---EPDSPAF 58
Query: 61 KLIPKLNSEDVIVVEGIVNFTPKAK-----LGFEIIPEKLEVISKAKTPLPLDPTGKVKA 115
+L +E V +EG P+++ FE+I +++V++ AKTP G+ A
Sbjct: 59 AEADRLRAEYVAEIEGTFQPRPESQRKGGLADFEVIASRVKVLNAAKTPPFELDKGESVA 118
Query: 116 ELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTE- 174
E D RL R++DLR P + +RS A EF EGFI++ TP + + EG +
Sbjct: 119 E-DIRLKYRYLDLRRPEMQRALMLRSKAVTAVTEFLDAEGFIQVETPMLTKSTPEGARDF 177
Query: 175 LFPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAE 233
L P + + + L QSPQL+KQ++M G D+ +++ FR E+ R + +D E
Sbjct: 178 LVPSRLNPGEFYALPQSPQLFKQLLMIAGFDRYYQLARCFRDEDLRADRQ-PDFTQLDME 236
Query: 234 MAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALE 290
M+F+E +++V+++ ERL+ +V ++L+ EL PFPR++Y +A++
Sbjct: 237 MSFVE-QDDVLEVQERLLAHVFR----------RVLDVEL---PLPFPRMSYFDAMD 279
Score = 72.6 bits (175), Expect = 8e-12
Identities = 37/88 (42%), Positives = 51/88 (57%), Gaps = 4/88 (4%)
Query: 351 KAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPES----FEFYLRAFEYGMPPHGGF 406
+A+DL G EI G R H ++ + + G + E+ F F+L A EYG PPHGG
Sbjct: 463 QAYDLVMNGFEIGGGSVRIHDPEVQAKMFQAIGFSEEAAREKFGFFLDALEYGTPPHGGI 522
Query: 407 GLGAERLIMRMLDIGNIREVILFPRDRR 434
G +RL+M M G+IREVI FP++ R
Sbjct: 523 AWGFDRLLMLMSGAGSIREVIAFPKNNR 550
>pir||D83183 lysyl-tRNA synthetase PA3700 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9949865|gb|AAG07088.1|AE004789_8
(AE004789) lysyl-tRNA synthetase [Pseudomonas
aeruginosa]
Length = 501
Score = 140 bits (350), Expect = 3e-32
Identities = 136/465 (29%), Positives = 212/465 (45%), Gaps = 49/465 (10%)
Query: 2 LRTHYSSEITEELNGKK--VKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEI 59
L+ Y+ + EEL VKVAG + L FI ++D +QV +K +P+E
Sbjct: 50 LQKQYADKTKEELEAAAIPVKVAGRIM----LNRGSFIVLQDSSERLQVYVNRKTLPEET 105
Query: 60 FKLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDT 119
I + D+I EG++ + K L ++ +L ++K+ PLP G E
Sbjct: 106 LAEIKTWDLGDIIGAEGVLARSGKGDLYVDMTSVRL--LTKSLRPLPDKHHGLTDTE--Q 161
Query: 120 RLDNRFMDLR-NPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPL 178
R R++DL N F++RS V R F + GF+E+ TP + GG P
Sbjct: 162 RYRQRYVDLMVNEETRHTFRVRSQVIAHIRRFLSERGFLEVETPML--QTIPGGAAAKPF 219
Query: 179 KYFENDA----FLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEM 234
+ N FL +P+LY + ++ G +KVFEI FR E +TRH E ++
Sbjct: 220 ETHHNALDMAMFLRIAPELYLKRLVVGGFEKVFEINRNFR-NEGVSTRHNPEFTMLEFYQ 278
Query: 235 AFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRIT-YDEALEI-- 291
A+ + E+ MDL E L + V + F EP F R++ +D L+
Sbjct: 279 AYADYEDN-MDLTEELFRELAQSVLGTTDVPYGDKVFHFGEP---FVRLSVFDSILKYNP 334
Query: 292 ------LSDLGKEIPWGEDIDTE--GEKLLGKY-------MLENEGAELYFIYRYPSEAK 336
L+D+ K + + G + LGK ++E++ + +FI RYP E
Sbjct: 335 EITAADLNDVEKARAIAKKAGAKVLGHEGLGKLQVMIFEELVEHKLEQPHFITRYPFEVS 394
Query: 337 PFYIMKYEDKPEVCKAFDLEYRGVEISSG----GQREHRHDILVEQIREKGLNPESFEFY 392
P ED P V F+L G EI++ E + + + Q++EK + Y
Sbjct: 395 PLARRNDED-PSVTDRFELFIGGREIANAYSELNDAEDQAERFMLQVKEKDAGDDEAMHY 453
Query: 393 ----LRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDR 433
+ A EYGMPP G G+G +RL+M + + +IR+VILFP R
Sbjct: 454 DADFINALEYGMPPTAGEGIGIDRLVMLLTNSPSIRDVILFPHMR 498
>sp|O87821|SYK_RHIME LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|3582260|gb|AAC35210.1| (M27221) lysyl-tRNA
synthetase [Sinorhizobium meliloti]
Length = 498
Score = 139 bits (348), Expect = 4e-32
Identities = 131/459 (28%), Positives = 218/459 (46%), Gaps = 59/459 (12%)
Query: 15 NGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVV 74
+G+ V VAG V ++ G F+ + D G +Q+ + K P+E L+P ++ D+I V
Sbjct: 59 SGETVTVAGRVFSSRNSG--MFMDLHDASGKIQIFSHKDTAPEEARALLPMIDLGDIIGV 116
Query: 75 EGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLR-NPRV 133
G V T + +L + +++ ++ K+ P+P G A+++TR R++D+ N
Sbjct: 117 TGEVRRTKRGEL--TVNAKEITMLCKSLLPMPEKYHGL--ADIETRYRKRYLDIMVNEES 172
Query: 134 MSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFEN----DAFLAQ 189
F+ RS + + R F EGF+E+ TP + GG P K N D +L
Sbjct: 173 KLRFQQRSRIVSSLRRFLEDEGFMEVETPML--QPIYGGATAEPFKTHHNTLKLDMYLRI 230
Query: 190 SPQLYKQMMMSTGL-DKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLE 248
+ +LY ++ +GL DKVFEI FR E +TRH E ++ A+ + E+ VM L+E
Sbjct: 231 AAELYLNAILVSGLTDKVFEINRNFR-NEGVSTRHNPEFTMMECYWAYADYED-VMGLVE 288
Query: 249 RLILYVINYVRENNEKEL--KILEFELNEPKKPFPRITY------------------DEA 288
R+ + V E E K L F K PFPR++ +EA
Sbjct: 289 RMFETLALAVHGKTEFEFGDKQLSF-----KGPFPRVSMPAASRTRPESISLPLKSDEEA 343
Query: 289 LEILSDLGKEIP----WGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYE 344
+ D G EI WGE + E+ + +++ + +P + PF +
Sbjct: 344 RQAARDAGVEIEKDATWGEVLAFLFEEKVEATLIQPA-----HVIHFPKDISPF-AKEVP 397
Query: 345 DKPEVCKAFDLEYRGVEISSGGQR-----EHRHDIL--VEQIREKGLNPESF-EFYLRAF 396
+P + + F+ G EI + E R ++ +EQ +G ++ E +L A
Sbjct: 398 GEPRLVERFETYCNGWEIGNAFSELNDPVEQRARMVEQMEQAHARGEKEKTLDEDFLDAM 457
Query: 397 EYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRRR 435
+ GMPP GG G+G +RLIM + + +IR++ILFP R++
Sbjct: 458 DQGMPPAGGLGIGVDRLIMLLTNSPSIRDIILFPARRQK 496
>sp|P73851|SYD_SYNY3 ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|7437584|pir||S75048 aspartate--tRNA ligase (EC
6.1.1.12) - Synechocystis sp. (strain PCC 6803)
>gi|1652993|dbj|BAA17910.1| (D90910) aspartyl-tRNA
synthetase [Synechocystis sp.]
Length = 599
Score = 139 bits (348), Expect = 4e-32
Identities = 92/300 (30%), Positives = 157/300 (51%), Gaps = 28/300 (9%)
Query: 2 LRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFK 61
+RTHY ++ G+ V + GWV +D GG+ F+ +RDR+GIVQ+ + + P +
Sbjct: 1 MRTHYCGDLRTTHLGETVTLYGWVDRRRDHGGVIFLDLRDRQGIVQIASSPDQTPAS-YP 59
Query: 62 LIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKA---------KTPLPLDPTGK 112
+ L +E V+ V G+V+ P L +I ++E+ + + + P +
Sbjct: 60 VAEGLRNEYVVQVTGVVSKRPPESLNEKIPTGEIEIYADSIILLNGVNQQLPFVVSSHEA 119
Query: 113 VKAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFY-KEGFIEIHTPKIIATATEG 171
+ D RL R++DLR R+ ++R V +A R F +E F+EI TP + + EG
Sbjct: 120 EQVREDVRLKYRYLDLRRARLSQNLQLRHQVVKAMRRFLEDQENFLEIETPILTRSTPEG 179
Query: 172 GTE-LFPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWS 229
+ L P + + + L QSPQL+KQ++M G+D+ ++I FR E+ R E
Sbjct: 180 ARDYLVPSRVNPGEWYALPQSPQLFKQLLMVAGMDRYYQIARCFRDEDLRADRQ-PEFTQ 238
Query: 230 IDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEAL 289
+D EM+F+ +EE++DL E LI ++ V+ ++ P +PFPR+TY E++
Sbjct: 239 LDMEMSFM-GQEEILDLNEALICHIFKVVK------------NIDLP-RPFPRLTYQESM 284
Score = 70.6 bits (170), Expect = 3e-11
Identities = 36/88 (40%), Positives = 52/88 (58%), Gaps = 4/88 (4%)
Query: 351 KAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPES----FEFYLRAFEYGMPPHGGF 406
+A+DL GVEI G R ++ ++ + GL+PE F F L AFEYG PPHGG
Sbjct: 478 QAYDLVMNGVEIGGGSLRIYQREVQEKVFATIGLSPEEAHEKFGFLLDAFEYGTPPHGGI 537
Query: 407 GLGAERLIMRMLDIGNIREVILFPRDRR 434
G +RL+M + +IR+VI FP+ ++
Sbjct: 538 AYGLDRLVMLLAKEDSIRDVIAFPKTQQ 565
>gb|AAF57921.1| (AE003804) CG6796 gene product [Drosophila melanogaster]
Length = 460
Score = 139 bits (347), Expect = 6e-32
Identities = 112/445 (25%), Positives = 202/445 (45%), Gaps = 44/445 (9%)
Query: 16 GKKVKVAGWVQEVKDLGGIKFIWIRD--REGIVQVTAPKKKVPQEIFKLIPKLNSEDVIV 73
G + + GW++ V+ L F+ I D QV P+ Q L VI
Sbjct: 24 GDSLAIQGWIKNVRRLKNNTFLDINDGSTSSRFQVVVPRTPENQH-------LAPGSVIA 76
Query: 74 VEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPRV 133
G + P FE+ ++E++++ + + K K + ++ + R V
Sbjct: 77 AVGKIQVAPNGS--FELHANQVEMLAEGRLQEGYPFSPKQKHPPEYVREHLHLRSRVDFV 134
Query: 134 MSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLK-------------- 179
+ ++R +A ++ + F++I+TP + EG E+F ++
Sbjct: 135 AAQMRVRHKAQKAIHDYMDDQDFVQINTPLLTTNDCEGAGEVFRVQPDSQDLLKQMNRPN 194
Query: 180 ------YFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAE 233
YF++ FL+ S QL+ + M + GL K + + P FRAE + HL E + +AE
Sbjct: 195 IPMEQSYFDSKVFLSVSGQLHLEAM-TYGLGKTYTLSPAFRAENSKSPLHLAEFYMFEAE 253
Query: 234 MAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEP------KKPFPRITYDE 287
+A +E E++ +E+++ V N + E + ++L + N + P+ ++YDE
Sbjct: 254 LAHLEEMEKLAQFIEQMLKSVTNRLLETSGEDLSFCQRNSNSNSDLPWLQVPWKIMSYDE 313
Query: 288 ALEILSDLGKEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKP 347
AL++L + + ++ K +++ + GA + F+ +P++ KPFY+ P
Sbjct: 314 ALQVLQENKDSLKTPISLNEGFSKDQELFLVAHCGAPV-FVVDWPAQQKPFYMKVSRSNP 372
Query: 348 EVCKAFDLEYRGV-EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGF 406
A DL V E+ G RE IL + P+ E+Y+ +YG P GGF
Sbjct: 373 NRVHALDLLMPAVGELCGGSLRESDPAIL----KSHPHLPKDLEWYVDLRKYGGVPTGGF 428
Query: 407 GLGAERLIMRMLDIGNIREVILFPR 431
G+G ER + + + NIR+VI FPR
Sbjct: 429 GMGFERYLQLVTGVKNIRDVIPFPR 453
>sp|P75068|SYD_MYCPN ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|2146065|pir||S73434 aspartate--tRNA ligase (EC
6.1.1.12) aspS - Mycoplasma pneumoniae (strain ATCC
29342) >gi|1673765|gb|AAB95756.1| (AE000013)
aspartyl-tRNA synthetase [Mycoplasma pneumoniae]
Length = 557
Score = 138 bits (344), Expect = 1e-31
Identities = 95/303 (31%), Positives = 156/303 (51%), Gaps = 27/303 (8%)
Query: 6 YSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPK 65
+ +T E K V +AGWV+ +K LG + F+ + D+ +QVT K+ +
Sbjct: 14 FIGNLTSEHLNKTVTIAGWVKRIKKLGELNFVIVGDKTNTIQVTCKNKEQ-------VKY 66
Query: 66 LNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRF 125
L ED+++V+G + + FEI + + +K+KTP PL K A + RL R+
Sbjct: 67 LTREDLVIVKGKLKRLDSVR--FEITNPTITLFAKSKTP-PLIIEDKTDALEEVRLRYRY 123
Query: 126 MDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTE-LFPLKYFEND 184
+DLR P + +R V A R + + GFIE+ TP + + EG + L P + E+
Sbjct: 124 LDLRRPVMQKRLALRHKVTLAVRNWLDQMGFIEVETPTLTKSTPEGARDFLVPARIREHS 183
Query: 185 AF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEV 243
+ L QSPQ+YKQ++M G +K F+I ++R E+ R E ID E+AF ++E V
Sbjct: 184 FYALPQSPQIYKQLLMVGGTEKYFQIAHVYRDEDSRKDRQ-PEHTQIDLEVAFY-TKEMV 241
Query: 244 MDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIPWGE 303
MDL++RL + V ++L +L KKPFP + + EA ++ +G
Sbjct: 242 MDLIQRLFVDVFR----------QVLNIKL---KKPFPVLKFAEAFNRFGSDKPDLRYGF 288
Query: 304 DID 306
+++
Sbjct: 289 ELE 291
Score = 74.9 bits (181), Expect = 2e-12
Identities = 36/102 (35%), Positives = 64/102 (62%), Gaps = 2/102 (1%)
Query: 333 SEAKPFYIMKYED-KPE-VCKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPESFE 390
S +P +++ +E+ K E + + +DL G E+ SG R H ++ ++ G++P+ F
Sbjct: 427 SNPQPQWLVNFENHKAEALSEQYDLVLNGFELGSGSIRIHDPEVQTRLMQSLGVDPQQFG 486
Query: 391 FYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRD 432
F + A++YG P H G GLG +RL+M + ++ NIREV+ FP++
Sbjct: 487 FVMEAYQYGAPVHAGMGLGLDRLMMIINNVDNIREVMAFPKN 528
>pir||A42609 lysine--tRNA ligase (EC 6.1.1.6) - Campylobacter jejuni
>gi|144208|gb|AAA23029.1| (M63448) transfer RNA-Lys
synthetase [Campylobacter jejuni]
Length = 501
Score = 137 bits (341), Expect = 3e-31
Identities = 124/446 (27%), Positives = 214/446 (47%), Gaps = 47/446 (10%)
Query: 21 VAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPK-LNSEDVIVVEGIVN 79
VAG ++ ++ G F I D + +Q+ K V +E++ ++ K L D+++V+G
Sbjct: 60 VAGRLKLLRIAGKSIFANIEDEDTNLQIYFSKDSVGEELYTILKKNLEVGDIVLVKGFPF 119
Query: 80 FTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDL-RNPRVMSIFK 138
T + F + ++++ +KA PLP G +++ R R++D+ N V F
Sbjct: 120 VTKTGE--FSLHASEVKLATKAIVPLPEKYHGLT--DIEQRYRKRYVDMIMNVEVRKDFL 175
Query: 139 IRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFEN----DAFLAQSPQLY 194
+RS V R FF +GF+E+ TP + A GG P F N + FL +P+LY
Sbjct: 176 VRSKVVSLIRHFFENKGFLEVETPMMHPIA--GGANAKPFVTFHNSLGVERFLRIAPELY 233
Query: 195 KQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYV 254
+ ++ G + VFEI FR E + T H E +I+ A+ + +++MDL E L +
Sbjct: 234 LKRLIVGGFEAVFEINRCFRNEGMDLT-HNPEFTTIEFYWAY-HNYKDLMDLTEELFALL 291
Query: 255 INYVRENNEKEL--KILEFELNEPKKPFPRITYDEALEILSDLGKEIPWGED-----IDT 307
++ + E K++ F KPF RITY +AL L +++ ++ +
Sbjct: 292 LDKLNLGKTIEFDGKMINFS-----KPFERITYKDALCKYGGLDRDLIEDKEKILTKLKA 346
Query: 308 EGEKLLGKYMLENEGAELY------------FIYRYPSEAKPFYIMKYEDKPEVCKAFDL 355
+G + K L + AEL+ F+ +P P ED ++ + F+L
Sbjct: 347 DGFEANEKLELGHLQAELFDNYVEEKLINPTFVIDFPISISPLSRRSDEDS-QIAERFEL 405
Query: 356 EYRGVEISSGGQREH----RHDILVEQIREKGLNPESF----EFYLRAFEYGMPPHGGFG 407
G E+++G + +++ ++QI K E E ++ A YGMPP G G
Sbjct: 406 FICGRELANGFNELNDPLDQYERFLKQIEAKNAGDEEACEMDEDFVNALGYGMPPTAGQG 465
Query: 408 LGAERLIMRMLDIGNIREVILFPRDR 433
+G +RL+M + + +IR+VILFP R
Sbjct: 466 IGIDRLVMLLTNKKSIRDVILFPAMR 491
>sp|P41258|SYK_CAMJE LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|11271343|pir||G81383 lysine--tRNA ligase (EC
6.1.1.6) Cj0401 [imported] - Campylobacter jejuni
(strain NCTC 11168) >gi|6967875|emb|CAB74237.1|
(AL139075) lysyl-tRNA synthetase [Campylobacter jejuni]
Length = 501
Score = 137 bits (341), Expect = 3e-31
Identities = 124/446 (27%), Positives = 214/446 (47%), Gaps = 47/446 (10%)
Query: 21 VAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPK-LNSEDVIVVEGIVN 79
VAG ++ ++ G F I D + +Q+ K V +E++ ++ K L D+++V+G
Sbjct: 60 VAGRLKLLRIAGKSIFANIEDEDTNLQIYFSKDSVGEELYTILKKNLEVGDIVLVKGFPF 119
Query: 80 FTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDL-RNPRVMSIFK 138
T + F + ++++ +KA PLP G +++ R R++D+ N V F
Sbjct: 120 VTKTGE--FSLHASEVKLATKAIVPLPEKYHGLT--DIEQRYRKRYVDMIMNVEVRKDFL 175
Query: 139 IRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFEN----DAFLAQSPQLY 194
+RS V R FF +GF+E+ TP + A GG P F N + FL +P+LY
Sbjct: 176 VRSKVVSLIRHFFENKGFLEVETPMMHPIA--GGANAKPFVTFHNSLGVERFLRIAPELY 233
Query: 195 KQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYV 254
+ ++ G + VFEI FR E + T H E +I+ A+ + +++MDL E L +
Sbjct: 234 LKRLIVGGFEAVFEINRCFRNEGMDLT-HNPEFTTIEFYWAY-HNYKDLMDLTEELFALL 291
Query: 255 INYVRENNEKEL--KILEFELNEPKKPFPRITYDEALEILSDLGKEIPWGED-----IDT 307
++ + E K++ F KPF RITY +AL L +++ ++ +
Sbjct: 292 LDKLNLGKTIEFDGKMINFS-----KPFERITYKDALCKYGGLDRDLIEDKEKILTKLKA 346
Query: 308 EGEKLLGKYMLENEGAELY------------FIYRYPSEAKPFYIMKYEDKPEVCKAFDL 355
+G + K L + AEL+ F+ +P P ED ++ + F+L
Sbjct: 347 DGFEANEKLELGHLQAELFDNYVEEKLINPTFVIDFPISISPLSRRSDEDS-QIAERFEL 405
Query: 356 EYRGVEISSGGQREH----RHDILVEQIREKGLNPESF----EFYLRAFEYGMPPHGGFG 407
G E+++G + +++ ++QI K E E ++ A YGMPP G G
Sbjct: 406 FICGRELANGFNELNDPLDQYERFLKQIEAKNAGDEEACEMDEDFVNALGYGMPPTAGQG 465
Query: 408 LGAERLIMRMLDIGNIREVILFPRDR 433
+G +RL+M + + +IR+VILFP R
Sbjct: 466 IGIDRLVMLLTNKKSIRDVILFPAMR 491
>sp|P57512|SYK_BUCAI LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|10039101|dbj|BAB13135.1| (AP001119) lysyl-tRNA
synthetase [Buchnera sp. APS]
Length = 506
Score = 137 bits (341), Expect = 3e-31
Identities = 120/445 (26%), Positives = 210/445 (46%), Gaps = 44/445 (9%)
Query: 18 KVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVEGI 77
+V +AG + + + +G F ++D EG +Q+ +KK+ + ++ D+ + G+
Sbjct: 67 EVSIAGRMVQRRIMGKASFFTLQDIEGKIQIYINEKKISSDFYRF--HFKKWDIGDILGV 124
Query: 78 VNFTPKAKLG-FEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDL-RNPRVMS 135
+ K K G I + + +++K+ PLP G E+ R R++DL N ++ S
Sbjct: 125 IGTLFKTKTGELSIYCKNVTILNKSLKPLPDKFHGLSNQEI--RYRKRYLDLISNNKLYS 182
Query: 136 IFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDA----FLAQSP 191
IFK RS++ A R F + F+E+ TP + GG P + N+ +L +P
Sbjct: 183 IFKNRSNIITAIRNFMIENDFLEVETPML--QNIPGGANARPFITYHNEIDSQMYLRIAP 240
Query: 192 QLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLI 251
+LY + ++ G +++FE+ FR E + RH E ++A +A+ + E++M+L E L
Sbjct: 241 ELYLKKLIIGGFERIFELNRNFR-NEGVSARHNPEFTMMEAYIAY-SNYEDMMELTENLF 298
Query: 252 LYVINYVRENNEKELKILEFELNEPKKPFPRITY-DEALEI--------LSDLGKEIPWG 302
+ ++ ++N+ F+ ++P F R+T D LE L D K +
Sbjct: 299 KSITKFLFQDNKIIFNNNNFDFSQP---FRRLTMTDSILEFNSTITSSDLKDFYKIREFA 355
Query: 303 EDIDTEGEKLLGKYMLENEGAELY---------FIYRYPSEAKPFYIMKYEDKPEVCKAF 353
+ I + EK G +E E E FI +YP E P + + + F
Sbjct: 356 KSIGIKVEKKWGCGQIETEIFEKTVEKKLIQPTFITQYPVEVSPL-ARRNDINLNITDRF 414
Query: 354 DLEYRGVEISSGGQR----EHRHDILVEQIREKGLNPESFEFY----LRAFEYGMPPHGG 405
+L G EI +G E + + QI++ FY + A +YG+PP G
Sbjct: 415 ELFIGGYEIGNGFSELNDVEDQKTRFLNQIQKSNKEDNKNLFYDKEYIEALKYGLPPTSG 474
Query: 406 FGLGAERLIMRMLDIGNIREVILFP 430
G+G +RLIM + + +IR+VILFP
Sbjct: 475 LGIGIDRLIMILTNQISIRDVILFP 499
>dbj|BAB15655.1| (AK027094) unnamed protein product [Homo sapiens]
Length = 250
Score = 137 bits (341), Expect = 3e-31
Identities = 90/251 (35%), Positives = 133/251 (52%), Gaps = 26/251 (10%)
Query: 199 MSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYVINYV 258
MS +VF GP FRAE + RHL E + I+AE++F++S +++M ++E L V
Sbjct: 1 MSGAFTQVFTFGPTFRAENSQSRRHLAEFYMIEAEISFVDSLQDLMQVIEELFKATTMMV 60
Query: 259 RENNEKELKI------------LEFELNEPKKPFPRITYDEALEILSDLGKEIP----WG 302
+++++ LE L K F I+Y EA+EIL + WG
Sbjct: 61 LSKCPEDVELCHKFIAPGQKDRLEHML---KNNFLIISYTEAVEILKQASQNFTFTPEWG 117
Query: 303 EDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPE-VCKAFDLEYRGV- 360
D+ TE EK Y++++ G F+ YP KPFY+ ED P+ A DL GV
Sbjct: 118 ADLRTEHEK----YLVKHCGNIPVFVINYPLTLKPFYMRDNEDGPQHTVAAVDLLVPGVG 173
Query: 361 EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDI 420
E+ GG RE R+ L E++ GL E +++YL +G PHGGFG+G ER + +L +
Sbjct: 174 ELFGGGLREERYHFLEERLARSGLT-EVYQWYLDLRRFGSVPHGGFGIGFERYLQCILGV 232
Query: 421 GNIREVILFPR 431
NI++VI FPR
Sbjct: 233 DNIKDVIPFPR 243
>pir||F82234 aspartyl-tRNA synthetase VC1166 [imported] - Vibrio cholerae (group
O1 strain N16961) >gi|9655641|gb|AAF94325.1| (AE004196)
aspartyl-tRNA synthetase [Vibrio cholerae]
Length = 591
Score = 136 bits (340), Expect = 4e-31
Identities = 96/297 (32%), Positives = 154/297 (51%), Gaps = 30/297 (10%)
Query: 2 LRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFK 61
+R+HY + + L G+ V++ GWV +DLGG+ FI +RDREGIVQV ++F
Sbjct: 1 MRSHYCGHLNKSLVGQTVELCGWVNRRRDLGGLIFIDMRDREGIVQVVVDPDMA--DVFA 58
Query: 62 LIPKLNSEDVIVVEGIVNFTPKAKLG-------FEIIPEKLEVISKAKTPLPLDPTGKVK 114
+ +L SE I + G V P++++ E++ LE+I+++ LPLD K
Sbjct: 59 VANQLRSEFCIKLTGEVRARPESQVNKEMATGEVELLARSLEIINRSDV-LPLDFNQKNS 117
Query: 115 AELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTE 174
E RL R++DLR P + K+R+ R F GF++I TP + EG +
Sbjct: 118 EE--QRLKYRYLDLRRPEMSDRIKLRAKASSFVRRFLDTHGFLDIETPVLTKATPEGARD 175
Query: 175 -LFPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDA 232
L P + + + L QSPQL+KQ++M +G D+ ++I FR E+ R E ID
Sbjct: 176 YLVPSRVHKGSFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQ-PEFTQIDI 234
Query: 233 EMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEAL 289
E +F+ + E+V + E++I E L++L +L + FP + Y EA+
Sbjct: 235 ETSFM-TAEQVRAVTEKMI----------REMWLELLNVDLGD----FPIMPYSEAM 276
>sp|P14825|SYK2_ECOLI LYSYL-TRNA SYNTHETASE, HEAT INDUCIBLE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|1361209|pir||S56358 lysine--tRNA ligase (EC 6.1.1.6)
- Escherichia coli >gi|7428467|pir||SYECKU lysine--tRNA
ligase (EC 6.1.1.6), thermoinducible - Escherichia coli
>gi|398703|emb|CAA34542.1| (X16542) lysyl-tRNA
synthetase (AA 1-505) [Escherichia coli]
>gi|536974|gb|AAA97029.1| (U14003) lysyl-tRNA synthetase
[Escherichia coli] >gi|1790571|gb|AAC77090.1| (AE000485)
lysine tRNA synthetase, inducible; heat shock protein
[Escherichia coli K12]
Length = 505
Score = 136 bits (338), Expect = 6e-31
Identities = 128/473 (27%), Positives = 209/473 (44%), Gaps = 54/473 (11%)
Query: 3 RTHYSSEITEELNGK----------KVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPK 52
R H S ++ EE + K +V VAG + + +G F+ ++D G +Q+ +
Sbjct: 42 RDHTSDQLHEEFDAKDNQELESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVAR 101
Query: 53 KKVPQEIFK-LIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTG 111
+P+ ++ K + D+I G + T +L +L +++KA PLP G
Sbjct: 102 DSLPEGVYNDQFKKWDLGDIIGARGTLFKTQTGELSIHCT--ELRLLTKALRPLPDKFHG 159
Query: 112 KVKAELDTRLDNRFMDL-RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATE 170
E+ R R++DL N + F +RS + A R+F GF+E+ TP +
Sbjct: 160 LQDQEV--RYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMM--QVIP 215
Query: 171 GGTELFPLKYFEN----DAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNE 226
GG P N D +L +P+LY + ++ G ++VFEI FR E + RH E
Sbjct: 216 GGASARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFR-NEGISVRHNPE 274
Query: 227 AWSIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYD 286
++ MA+ + + +++L E L + V + F+ KPF ++T
Sbjct: 275 FTMMELYMAYADYHD-LIELTESLFRTLAQEVLGTTKVTYGEHVFDFG---KPFEKLTMR 330
Query: 287 EALEILS-----------DLGKEIPWGEDIDTEGEKLLGKYMLE--NEGAELY-----FI 328
EA++ D K + I E LG+ + E +E AE + FI
Sbjct: 331 EAIKKYRPETDMADLDNFDAAKALAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQPTFI 390
Query: 329 YRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSG----GQREHRHDILVEQIREKGL 384
YP+E P + + PE+ F+ G EI +G E + + EQ+ K
Sbjct: 391 TEYPAEVSPL-ARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAA 449
Query: 385 NPESFEFY----LRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDR 433
+ FY + A EYG+PP G G+G +R+IM + IR+VILFP R
Sbjct: 450 GDDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMIMLFTNSHTIRDVILFPAMR 502
>pdb|1E1O|A Chain A, Lysyl-Trna Synthetase (Lysu) Hexagonal For, Complexed With
L >gi|9954997|pdb|1E1T|A Chain A, Lysyl-Trna Synthetase
(Lysu) Hexagonal Form Complexed With T Lysyl_adenylate
Intermediate >gi|9954998|pdb|1E22|A Chain A, Lysyl-Trna
Synthetase (Lysu) Hexagonal Form Complexed With Lysine
And The Non-Hydrolysable Atp Analogue Amp-Pcp
>gi|9954999|pdb|1E24|A Chain A, Lysyl-Trna Synthetase
(Lysu) Hexagonal Form Complexed With Lysine And Atp And
Mn2+ >gi|1311301|pdb|1LYL|A Chain A, Lysyl-Trna
Synthetase (Lysu) (E.C.6.1.1.6) Complexed With Lysine
>gi|1311305|pdb|1LYL|C Chain C, Lysyl-Trna Synthetase
(Lysu) (E.C.6.1.1.6) Complexed With Lysine
>gi|1311303|pdb|1LYL|B Chain B, Lysyl-Trna Synthetase
(Lysu) (E.C.6.1.1.6) Complexed With Lysine
Length = 504
Score = 136 bits (338), Expect = 6e-31
Identities = 128/473 (27%), Positives = 209/473 (44%), Gaps = 54/473 (11%)
Query: 3 RTHYSSEITEELNGK----------KVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPK 52
R H S ++ EE + K +V VAG + + +G F+ ++D G +Q+ +
Sbjct: 41 RDHTSDQLHEEFDAKDNQELESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVAR 100
Query: 53 KKVPQEIFK-LIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTG 111
+P+ ++ K + D+I G + T +L +L +++KA PLP G
Sbjct: 101 DSLPEGVYNDQFKKWDLGDIIGARGTLFKTQTGELSIHCT--ELRLLTKALRPLPDKFHG 158
Query: 112 KVKAELDTRLDNRFMDL-RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATE 170
E+ R R++DL N + F +RS + A R+F GF+E+ TP +
Sbjct: 159 LQDQEV--RYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMM--QVIP 214
Query: 171 GGTELFPLKYFEN----DAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNE 226
GG P N D +L +P+LY + ++ G ++VFEI FR E + RH E
Sbjct: 215 GGASARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFR-NEGISVRHNPE 273
Query: 227 AWSIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYD 286
++ MA+ + + +++L E L + V + F+ KPF ++T
Sbjct: 274 FTMMELYMAYADYHD-LIELTESLFRTLAQEVLGTTKVTYGEHVFDFG---KPFEKLTMR 329
Query: 287 EALEILS-----------DLGKEIPWGEDIDTEGEKLLGKYMLE--NEGAELY-----FI 328
EA++ D K + I E LG+ + E +E AE + FI
Sbjct: 330 EAIKKYRPETDMADLDNFDAAKALAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQPTFI 389
Query: 329 YRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSG----GQREHRHDILVEQIREKGL 384
YP+E P + + PE+ F+ G EI +G E + + EQ+ K
Sbjct: 390 TEYPAEVSPL-ARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAA 448
Query: 385 NPESFEFY----LRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDR 433
+ FY + A EYG+PP G G+G +R+IM + IR+VILFP R
Sbjct: 449 GDDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMIMLFTNSHTIRDVILFPAMR 501
>sp|O67258|SYK_AQUAE LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|7437570|pir||G70403 lysine--tRNA ligase (EC 6.1.1.6)
- Aquifex aeolicus >gi|2983651|gb|AAC07218.1| (AE000728)
lysyl-tRNA synthetase [Aquifex aeolicus]
Length = 597
Score = 134 bits (334), Expect = 2e-30
Identities = 119/447 (26%), Positives = 215/447 (47%), Gaps = 40/447 (8%)
Query: 15 NGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPK-LNSEDVIV 73
N + V +AG + ++ +G F I+D G +Q+ K + +E K ++ D++
Sbjct: 150 NFRPVSLAGRLVSMRSMGKAIFGHIQDLTGKIQIYLKKDVIGEEKLKFFNDYIDVGDIVG 209
Query: 74 VEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDL-RNPR 132
V G + T +L E+ E+ ++++K+ PLP G +++ R R++DL NP
Sbjct: 210 VRGKLFRTNTGELTVEV--EEYQLLAKSLHPLPEKWHGL--KDVEVRYRQRYLDLIANPE 265
Query: 133 VMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPL--KYFENDAFLAQS 190
IF +R+ + R+FF GFIE+ TP + A+ F + E + +L +
Sbjct: 266 ARRIFMLRTKLITEMRKFFEMHGFIEVETPILQPIASGANARPFVTYHNFLETELYLRIA 325
Query: 191 PQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERL 250
P+LY + ++ G +V+EIG FR E + T H E ++ A+ + + ++ E +
Sbjct: 326 PELYLKRLIVGGFPRVYEIGKNFRNESVDRT-HNPEFTMVEFYAAYWDYHD-LIKFTEDM 383
Query: 251 ILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEAL---------------EILSDL 295
+Y++ + ++K E+EL+ PF ++ Y + L E L L
Sbjct: 384 FVYLLE--KTLGTLKVKYGEWELDF-SPPFKKVRYFDLLKEKTGKDKDFFLKDLEGLRKL 440
Query: 296 GKEIPWGEDIDTEGEKLLGKY---MLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKA 352
KE+ + KLL K + E + + F+ +P P ED P++ +
Sbjct: 441 AKELEIPDVERMTHAKLLDKVFEKVAEEDLIQPTFVIDFPKILSPLAKTHRED-PDLVER 499
Query: 353 FDLEYRGVEISSGGQREH----RHDILVEQIREKGLNPESF----EFYLRAFEYGMPPHG 404
F+L E+++ + + + +EQ++EK + E E ++RA EYGMPP
Sbjct: 500 FELIIARYEVANAYTELNDPFDQKERFLEQLKEKQMGDEEAMDMDEDFIRALEYGMPPTA 559
Query: 405 GFGLGAERLIMRMLDIGNIREVILFPR 431
G G+G +RL+M + + +IREVILFP+
Sbjct: 560 GEGIGIDRLVMILANTDSIREVILFPQ 586
>sp|P47282|SYD_MYCGE ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|1361448|pir||I64203 aspartate--tRNA ligase (EC
6.1.1.12) - Mycoplasma genitalium
>gi|3844646|gb|AAC71252.1| (U39683) aspartyl-tRNA
synthetase (aspS) [Mycoplasma genitalium]
Length = 550
Score = 134 bits (333), Expect = 3e-30
Identities = 91/297 (30%), Positives = 152/297 (50%), Gaps = 28/297 (9%)
Query: 11 TEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSED 70
TE+LN K + + GW++ +K LG I FI + D+ G +QVT K + I +L ED
Sbjct: 14 TEQLN-KTIVIIGWIKRIKKLGEINFIIVGDKSGTIQVTCKDK-------EQIQQLTRED 65
Query: 71 VIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRN 130
+++V+ + + FE+I +++ SK+KTP PL + A + RL R++DLR
Sbjct: 66 IVIVKAKLQRLDSVR--FELINPTIKLFSKSKTP-PLIIEDETDALEEVRLKYRYLDLRR 122
Query: 131 PRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAF--LA 188
+ +R A R +F ++GFIEI TP + + EG + D F L
Sbjct: 123 RLMQKRLLLRHQFILAIRNWFNQQGFIEIETPTLSKSTPEGAQDFLVPARIRKDCFYALV 182
Query: 189 QSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLE 248
QSPQ+YKQ++M G++K F+I ++R E+ R E ID E++F +++ +M+L+E
Sbjct: 183 QSPQIYKQLLMIAGVEKYFQIARVYRDEDSRKDRQ-PEHTQIDFEISFC-NQKMIMNLVE 240
Query: 249 RLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIPWGEDI 305
+L V L + + ++ KK FP + E E ++ +G +I
Sbjct: 241 KLFFSVF----------LDVFQIKI---KKTFPVFKFSELFERFGSDKPDLRYGFEI 284
Score = 69.5 bits (167), Expect = 7e-11
Identities = 38/102 (37%), Positives = 55/102 (53%), Gaps = 2/102 (1%)
Query: 333 SEAKPFYIMKYEDKPE--VCKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPESFE 390
S+ K +I +E + + FDL G EI SG R + + + ++P F
Sbjct: 421 SKPKQEWIDNFESNKNEALSEQFDLVLNGFEIGSGSIRINDPIVQKRLMNSLNIDPNKFA 480
Query: 391 FYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRD 432
F L A++YG P HGG GLG +RL+M + NIREVI FP++
Sbjct: 481 FLLEAYQYGAPVHGGMGLGIDRLMMILNQTDNIREVIAFPKN 522
>sp|Q9ZMP8|SYK_HELPJ LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|7437567|pir||F71965 lysine--tRNA ligase (EC 6.1.1.6)
- Helicobacter pylori (strain J99)
>gi|4154685|gb|AAD05751.1| (AE001455) LYSYL-TRNA
SYNTHETASE [Helicobacter pylori J99]
Length = 501
Score = 134 bits (333), Expect = 3e-30
Identities = 119/443 (26%), Positives = 207/443 (45%), Gaps = 43/443 (9%)
Query: 21 VAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVEGIVNF 80
V G V+ ++ +G FI I D I+Q + ++ E L L D+++V+G
Sbjct: 60 VVGRVKLLRLMGKACFIKIEDESAILQAYVSQNELNDEFKSLKKHLEVGDIVLVKGFPFA 119
Query: 81 TPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLR-NPRVMSIFKI 139
T +L + + ++SK PLP G ++++ R R++DL NP V +FK
Sbjct: 120 TKTGELSIHAL--EFHILSKTIVPLPEKFHGL--SDIELRYRQRYLDLIVNPGVKDVFKK 175
Query: 140 RSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFEN----DAFLAQSPQLYK 195
RS + + R+FF EGF+E+ TP + GG P + N + +L +P+LY
Sbjct: 176 RSLIVSSVRKFFEMEGFLEVETPMM--HPIPGGANARPFITYHNALEIERYLRIAPELYL 233
Query: 196 QMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYVI 255
+ ++ G + VFEI FR E + + H E I+ A+ + E++++L +RL Y++
Sbjct: 234 KRLIVGGFEAVFEINRNFRNEGMDHS-HNPEFTMIEFYWAY-HTYEDLIELSKRLFDYLL 291
Query: 256 NYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIPWGED----------I 305
+ +++ +E + N+ I+Y +ALE + + K I ED I
Sbjct: 292 KTLNLDSKIIYNDMEVDFNQTSV----ISYLDALETIGGISKGILEKEDRLLAYLLEQGI 347
Query: 306 DTEGEKLLGK-------YMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYR 358
E GK + +E++ F+ YP E P + + P + F+L
Sbjct: 348 KVEPNLTHGKLLAEAFDHFVEHKLINPTFVTEYPIEISPL-ARRNDSNPNIADRFELFIA 406
Query: 359 GVEISSGGQREH----RHDILVEQIREKGLNPESFEF----YLRAFEYGMPPHGGFGLGA 410
G EI++G + + + Q+ EK E ++ Y+ A + MPP G G+G
Sbjct: 407 GKEIANGFSELNDPLDQLERFKNQVAEKEKGDEEAQYMDEDYVWALAHEMPPTAGQGIGI 466
Query: 411 ERLIMRMLDIGNIREVILFPRDR 433
+RL+M + +I++VILFP R
Sbjct: 467 DRLVMLLTGAKSIKDVILFPAMR 489
>pir||G81412 aspartate--tRNA ligase (EC 6.1.1.12) Cj0640c [imported] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6968107|emb|CAB75276.1| (AL139075) aspartyl-tRNA
synthetase [Campylobacter jejuni]
Length = 583
Score = 134 bits (333), Expect = 3e-30
Identities = 91/298 (30%), Positives = 150/298 (49%), Gaps = 28/298 (9%)
Query: 2 LRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFK 61
+R+HY++++ G+ VK+ GWV +D GG+ FI +RDR GI+Q+ +E +
Sbjct: 1 MRSHYNTDLGISHVGQSVKLCGWVNSYRDHGGVIFIDLRDRSGIIQLVCDPND-SKEAHE 59
Query: 62 LIPKLNSEDVIVVEGIVN------FTPKAKLG-FEIIPEKLEVISKAKTPLPLDPTGKVK 114
+ +E V++ EG + PK K G E++ KL + +++ P V
Sbjct: 60 IASNARNEFVLITEGTIRPRGEGLVNPKLKTGEIEVVVSKLTIENESAVPPFAIADESVN 119
Query: 115 AELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTE 174
EL RL RF+DLRNP++ F +RS A R GF+E+ TP + EG +
Sbjct: 120 EEL--RLKYRFLDLRNPKLYENFALRSKACIAARNSLANMGFLEVETPILTKATPEGARD 177
Query: 175 -LFPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDA 232
L P + + + + L QSPQL+KQ++M +G D+ F+I FR E+ R E ID
Sbjct: 178 YLVPSRVHQGEFYALPQSPQLFKQLLMCSGFDRYFQIAKCFRDEDLRADRQ-PEFTQIDV 236
Query: 233 EMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALE 290
EM+F E +++V+ + E + + + E + PF ++ Y +A+E
Sbjct: 237 EMSFCE-QKDVIKVAETFLKDIFKACGK--------------EIQTPFRQMQYKDAME 279
>gb|AAK40448.1| Lysyl-tRNA synthetase (lysS) [Sulfolobus solfataricus]
Length = 494
Score = 132 bits (330), Expect = 6e-30
Identities = 124/449 (27%), Positives = 215/449 (47%), Gaps = 58/449 (12%)
Query: 19 VKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVEGIV 78
+ AG V ++ G F+ I D +Q+ ++ ++ K + D+I V+G +
Sbjct: 56 ISTAGRVANIRRHGKASFVDIFDEGEKLQLYMRVDELKEKYDKFFIYVGRGDIIGVKGDL 115
Query: 79 NFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMD-LRNPRVMSIF 137
+T K +L ++ + +++SKA ++P K + R +R++D L N
Sbjct: 116 FYTMKGELS--LLVKDYQLLSKAL----IEPPDWSKLSPEFRYAHRYVDFLYNDNARKAM 169
Query: 138 KIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLK----YFENDAFLAQSPQL 193
+IR ++ R REF Y +GFIE+ TP I GG P K Y D +L + +L
Sbjct: 170 EIRYTIIREIREFLYSKGFIEVETP--IVQPVYGGALAKPFKTHVNYLNEDWYLRIALEL 227
Query: 194 YKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILY 253
Y + + G +KVFEIG +FR E+ + T H E ++ A+ + + +M+L E L+
Sbjct: 228 YLKRYIIGGFNKVFEIGKVFRNEDIDVT-HNPEFTLLELYWAYADYND-IMNLTEDLLKS 285
Query: 254 VINYVRENNEKELKILEFELNEPKKPFPRIT-YDEALEILSDLGKEIPWGEDIDTEGEKL 312
V+ V N ++ ++E++ + PF RI+ YD EIL GK++ D E ++L
Sbjct: 286 VVKKV--TNSTKIVYGKYEIDF-EGPFKRISMYDSLSEIL---GKDVE--SMSDNELKEL 337
Query: 313 LGKYMLENEGAELY---------------------FIYRYPSEAKPFYIMKYEDKPEVCK 351
+ KY L G + FI YP E P + +KP + +
Sbjct: 338 MKKYNLTPRGNQYVRGLMIEKLFDKLVTPTLTNPTFITDYPIETTPL-CKPHRNKPGLVE 396
Query: 352 AFDLEYRGVEISSGGQREHRHDILVEQI----------REKGLNPESFEFYLRAFEYGMP 401
F++ G+E+++ E IL +++ ++ +P +F +RA YGMP
Sbjct: 397 RFEMFIAGMEVANA-YTELNDPILQDKLFREEQEMFRRGDEEAHPYDKDF-VRALSYGMP 454
Query: 402 PHGGFGLGAERLIMRMLDIGNIREVILFP 430
P GG G+G +R++M + + +I+EVI FP
Sbjct: 455 PTGGLGIGIDRIVMLVTNNYSIKEVIPFP 483
>sp|P95970|SYK_SULSO LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|7437603|pir||S75398 lysine--tRNA ligase (EC 6.1.1.6)
- Sulfolobus solfataricus >gi|1707804|emb|CAA69561.1|
(Y08257) lysyl tRNA synthetase [Sulfolobus solfataricus]
Length = 494
Score = 132 bits (330), Expect = 6e-30
Identities = 124/449 (27%), Positives = 215/449 (47%), Gaps = 58/449 (12%)
Query: 19 VKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVEGIV 78
+ AG V ++ G F+ I D +Q+ ++ ++ K + D+I V+G +
Sbjct: 56 ISTAGRVANIRRHGKASFVDIFDEGEKLQLYMRVDELKEKYDKFFIYVGRGDIIGVKGDL 115
Query: 79 NFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMD-LRNPRVMSIF 137
+T K +L ++ + +++SKA ++P K + R +R++D L N
Sbjct: 116 FYTMKGELS--LLVKDYQLLSKAL----IEPPDWSKLSPEFRYAHRYVDFLYNDNARKAM 169
Query: 138 KIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLK----YFENDAFLAQSPQL 193
+IR ++ R REF Y +GFIE+ TP I GG P K Y D +L + +L
Sbjct: 170 EIRYTIIREIREFLYSKGFIEVETP--IVQPVYGGALAKPFKTHVNYLNEDWYLRIALEL 227
Query: 194 YKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILY 253
Y + + G +KVFEIG +FR E+ + T H E ++ A+ + + +M+L E L+
Sbjct: 228 YLKRYIIGGFNKVFEIGKVFRNEDIDVT-HNPEFTLLELYWAYADYND-IMNLTEDLLKS 285
Query: 254 VINYVRENNEKELKILEFELNEPKKPFPRIT-YDEALEILSDLGKEIPWGEDIDTEGEKL 312
V+ V N ++ ++E++ + PF RI+ YD EIL GK++ D E ++L
Sbjct: 286 VVKKV--TNSTKIVYGKYEIDF-EGPFKRISMYDSLSEIL---GKDVE--SMSDNELKEL 337
Query: 313 LGKYMLENEGAELY---------------------FIYRYPSEAKPFYIMKYEDKPEVCK 351
+ KY L G + FI YP E P + +KP + +
Sbjct: 338 MKKYNLTPRGNQYVRGLMIEKLFDKLVTPTLTNPTFITDYPIETTPL-CKPHRNKPGLVE 396
Query: 352 AFDLEYRGVEISSGGQREHRHDILVEQI----------REKGLNPESFEFYLRAFEYGMP 401
F++ G+E+++ E IL +++ ++ +P +F +RA YGMP
Sbjct: 397 RFEMFIAGMEVANA-YTELNDPILQDKLFREEQEMFRRGDEEAHPYDKDF-VRALSYGMP 454
Query: 402 PHGGFGLGAERLIMRMLDIGNIREVILFP 430
P GG G+G +R++M + + +I+EVI FP
Sbjct: 455 PTGGLGIGIDRIVMLVTNNYSIKEVIPFP 483
>sp|P43825|SYK_HAEIN LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|1074993|pir||D64110 lysine--tRNA ligase (EC 6.1.1.6)
- Haemophilus influenzae (strain Rd KW20)
>gi|1574141|gb|AAC22865.1| (U32800) lysyl-tRNA
synthetase (lysU) [Haemophilus influenzae Rd]
Length = 502
Score = 132 bits (329), Expect = 7e-30
Identities = 130/470 (27%), Positives = 216/470 (45%), Gaps = 48/470 (10%)
Query: 2 LRTHYSSEITEELNGK--KVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEI 59
L Y +E E L K +V+VAG + + +G FI I+D G +Q+ + +P+ +
Sbjct: 45 LHNQYDAEDGEILKEKGIEVQVAGRIMTRRAMGKATFITIQDMSGKIQLYVARDNLPEGV 104
Query: 60 FKL-IPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELD 118
+K + + D++ ++G + T +L + ++++++KA PLP G E+
Sbjct: 105 YKDDVGTWDLGDIVGIKGTLFKTKTDEL--TVKTTEVQLLTKALRPLPDKFHGLTDQEV- 161
Query: 119 TRLDNRFMDL-RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFP 177
R R++DL N F IRS V RE+F +GF+E+ TP + GG P
Sbjct: 162 -RYRQRYLDLISNEESRRTFIIRSKVVAGIREYFISKGFMEVETPML--QVIPGGASARP 218
Query: 178 LKYFEN----DAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAE 233
N D +L +P+LY + ++ G ++VFE+ FR E + RH E ++
Sbjct: 219 FVTHHNALDVDMYLRIAPELYLKRLVVGGFERVFELNRNFR-NEGVSVRHNPEFTMLEYY 277
Query: 234 MAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEAL---- 289
A+ + + +MD E L+ + + + LEF+ KPF RIT +A
Sbjct: 278 QAYADYHD-LMDNTEELLRKLAIDILGTTIVKYGDLEFDFG---KPFERITLHDATIKYG 333
Query: 290 -------EILSDLGKEIPWGEDIDTEGEKLLGKYMLEN----EGAELY-----FIYRYPS 333
E L D + E + E +K G + N E AE + F+ P+
Sbjct: 334 ADKGIVKEDLYDFDRAKATAERLGIEVQKSWGLGSIVNAIFEEVAEHHLIQPTFLNGSPA 393
Query: 334 EAKPFYIMKYEDKPEVCKAFDLEYRGVEISSG----GQREHRHDILVEQIREKGLNPESF 389
E P + ++ PEV F+L G EI +G E +++ Q+ K +
Sbjct: 394 EISPL-ARRNDENPEVTDRFELFIGGREIGNGFSELNDAEDQNERFDAQVAAKEAGDDEA 452
Query: 390 EF----YLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRRR 435
F ++ A E+G+PP G GLG +RL M + +IR+VILFP R++
Sbjct: 453 MFKDEDFVVALEHGLPPTAGEGLGIDRLAMLYANAPSIRDVILFPAMRQK 502
>pir||G81195 aspartyl-tRNA synthetase NMB0466 [imported] - Neisseria
meningitidis (group B strain MD58)
>gi|7225693|gb|AAF40903.1| (AE002403) aspartyl-tRNA
synthetase [Neisseria meningitidis MC58]
Length = 602
Score = 132 bits (328), Expect = 1e-29
Identities = 96/297 (32%), Positives = 148/297 (49%), Gaps = 29/297 (9%)
Query: 2 LRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFK 61
+RT+Y I+E+ + V V GWV +D GG+ FI +RDREGIVQV E F
Sbjct: 1 MRTNYCGLISEQYLDQTVTVKGWVHRRRDHGGVIFIDLRDREGIVQVVIDPD--TPEAFA 58
Query: 62 LIPKLNSEDVIVVEGIVNFTPKAKLG-------FEIIPEKLEVISKAKTPLPLDPTGKVK 114
+E V+ + G V P+ EI+ +++EV++ A TP P +
Sbjct: 59 AADSSRNEYVLSITGRVRNRPEGTTNDKMISGKIEILAKEIEVLNAAATP-PFQIDDENI 117
Query: 115 AELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTE 174
+E + RL NR +DLR P + ++R V R + +GFI+I TP + + EG +
Sbjct: 118 SE-NVRLTNRVIDLRRPVMQRNLRLRYQVAMGVRRYLDAQGFIDIETPMLTRSTPEGARD 176
Query: 175 -LFPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDA 232
L P + + F L QSPQL+KQ++M G D+ ++I FR E+ R E ID
Sbjct: 177 YLVPSRVHPGEFFALPQSPQLFKQLLMVAGFDRYYQITKCFRDEDLRADRQ-PEFTQIDL 235
Query: 233 EMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEAL 289
E +F+ +E+E+MD+ E + ++ + LN FPR+ Y EA+
Sbjct: 236 ETSFL-NEDEIMDITEGM--------------AKQVFKDALNVDLGDFPRMPYSEAM 277
>sp|P13030|SYK1_ECOLI LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|7428466|pir||SYECKT lysine--tRNA ligase (EC 6.1.1.6)
- Escherichia coli >gi|146341|gb|AAA23959.1| (J03795)
herC protein [Escherichia coli]
>gi|887840|gb|AAA83071.1| (U28375) lysyl tRNA synthetase
(LysRS), constitutive [Escherichia coli]
>gi|1789256|gb|AAC75928.1| (AE000372) lysine tRNA
synthetase, constitutive; suppressor of ColE1 mutation
in primer RNA [Escherichia coli K12]
Length = 505
Score = 131 bits (327), Expect = 1e-29
Identities = 124/473 (26%), Positives = 210/473 (44%), Gaps = 54/473 (11%)
Query: 3 RTHYSSEITEELNGKK----------VKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPK 52
R H S ++ E +GK+ V VAG + + +G F+ ++D G +Q+ +
Sbjct: 42 RDHTSDQLHAEFDGKENEELEALNIEVAVAGRMMTRRIMGKASFVTLQDVGGRIQLYVAR 101
Query: 53 KKVPQEIF-KLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTG 111
+P+ ++ + K + D++ +G + T +L +L +++KA PLP G
Sbjct: 102 DDLPEGVYNEQFKKWDLGDILGAKGKLFKTKTGELSIHCT--ELRLLTKALRPLPDKFHG 159
Query: 112 KVKAELDTRLDNRFMDL-RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATE 170
E R R++DL N + FK+RS + R+F GF+E+ TP +
Sbjct: 160 LQDQE--ARYRQRYLDLISNDESRNTFKVRSQILSGIRQFMVNRGFMEVETPMM--QVIP 215
Query: 171 GGTELFPLKYFEN----DAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNE 226
GG P N D +L +P+LY + ++ G ++VFEI FR E + RH E
Sbjct: 216 GGAAARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFR-NEGISVRHNPE 274
Query: 227 AWSIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYD 286
++ MA+ + ++ +++L E L + + E + + KPF ++T
Sbjct: 275 FTMMELYMAYADYKD-LIELTESLFRTLAQDILGKTEVTYGDVTLDFG---KPFEKLTMR 330
Query: 287 EALEILS-----------DLGKEIPWGEDIDTEGEKLLGKYMLE--NEGAELY-----FI 328
EA++ D K I I E LG+ + E E AE + FI
Sbjct: 331 EAIKKYRPETDMADLDNFDSAKAIAESIGIHVEKSWGLGRIVTEIFEEVAEAHLIQPTFI 390
Query: 329 YRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSG----GQREHRHDILVEQIREKGL 384
YP+E P + + PE+ F+ G EI +G E + ++Q+ K
Sbjct: 391 TEYPAEVSPL-ARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAQRFLDQVAAKDA 449
Query: 385 NPESFEFY----LRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDR 433
+ FY + A E+G+PP G G+G +R++M + IR+VILFP R
Sbjct: 450 GDDEAMFYDEDYVTALEHGLPPTAGLGIGIDRMVMLFTNSHTIRDVILFPAMR 502
>sp|Q9KGG4|SYK_BACHD LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|10172710|dbj|BAB03817.1| (AP001507) lysyl-tRNA
synthetase [Bacillus halodurans]
Length = 501
Score = 131 bits (327), Expect = 1e-29
Identities = 126/475 (26%), Positives = 224/475 (46%), Gaps = 56/475 (11%)
Query: 2 LRTHYSSEITEELNGK--KVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEI 59
++ Y ++ EEL + +V +AG V + G F I+D G +Q+ K V +
Sbjct: 42 MKEKYDAKSKEELEEETHEVVLAGRVMTKRGKGKAGFAHIQDLTGQIQIYVRKDAVGDKS 101
Query: 60 FKLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDT 119
+ L ++ D++ V+G+ T +L ++ + ++++K+ PLP D +K +++
Sbjct: 102 YDLFTSIDIGDIVGVKGVAFKTKVGELSVKV--QDFQLLTKSLRPLP-DKYHGLK-DVEQ 157
Query: 120 RLDNRFMDLR-NPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPL 178
R R++DL NP V F +RS + ++ R + G++E+ TP + + GG P
Sbjct: 158 RYRQRYLDLIVNPEVRDTFVLRSKILQSMRRYLDDRGYLEVETPTM--HSIPGGASARPF 215
Query: 179 KYFEN----DAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEM 234
N ++ + +L+ + ++ G++KV+EIG +FR E +TRH E I+
Sbjct: 216 VTHHNALDMTLYMRIAIELHLKRLIVGGMEKVYEIGRVFR-NEGVSTRHNPEFTMIELYE 274
Query: 235 AFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELN-EPKKPFPRITYDEALEILS 293
A+ + + +M+L E LI ++ V + E E+N EPK + R+ EA++
Sbjct: 275 AYADYND-IMELTELLIAHIAKDVLGTTT--ITYGEHEVNLEPK--WRRVHMVEAIK--E 327
Query: 294 DLGKEIPWGEDIDTEGEKLLGKY--------------------MLENEGAELYFIYRYPS 333
+ G + W E D E L ++ +E + + F+Y +P
Sbjct: 328 ETGVDF-WNEMSDEEARALAKEHNVPVKETMTYGHVVNEFFEHFVEEKLIQPTFVYGHPV 386
Query: 334 EAKPFYIMKYEDKPEVCKAFDLEYRGVEISSG--------GQREHRHDILVEQIREKGLN 385
P K D P F+L G E ++ QR LVE RE+G +
Sbjct: 387 AISPL-AKKNPDDPRFTDRFELFIVGREHANAFSELNDPIDQRHRFEQQLVE--REQGDD 443
Query: 386 PESF--EFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRRRLVP 438
E ++ + EYGMPP GG G+G +RL+M + + +IR+V+LFP+ R + P
Sbjct: 444 EAHMMDEDFVESLEYGMPPTGGLGIGIDRLVMLLTNSPSIRDVLLFPQMRHKDSP 498
>pdb|1BBU|A Chain A, Lysyl-Trna Synthetase (Lyss) Complexed With Lysine
>gi|11513776|pdb|1BBW|A Chain A, Lysyl-Trna Synthetase
(Lyss)
Length = 504
Score = 131 bits (327), Expect = 1e-29
Identities = 124/473 (26%), Positives = 210/473 (44%), Gaps = 54/473 (11%)
Query: 3 RTHYSSEITEELNGKK----------VKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPK 52
R H S ++ E +GK+ V VAG + + +G F+ ++D G +Q+ +
Sbjct: 41 RDHTSDQLHAEFDGKENEELEALNIEVAVAGRMMTRRIMGKASFVTLQDVGGRIQLYVAR 100
Query: 53 KKVPQEIF-KLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTG 111
+P+ ++ + K + D++ +G + T +L +L +++KA PLP G
Sbjct: 101 DDLPEGVYNEQFKKWDLGDILGAKGKLFKTKTGELSIHCT--ELRLLTKALRPLPDKFHG 158
Query: 112 KVKAELDTRLDNRFMDL-RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATE 170
E R R++DL N + FK+RS + R+F GF+E+ TP +
Sbjct: 159 LQDQE--ARYRQRYLDLISNDESRNTFKVRSQILSGIRQFMVNRGFMEVETPMM--QVIP 214
Query: 171 GGTELFPLKYFEN----DAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNE 226
GG P N D +L +P+LY + ++ G ++VFEI FR E + RH E
Sbjct: 215 GGAAARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFR-NEGISVRHNPE 273
Query: 227 AWSIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYD 286
++ MA+ + ++ +++L E L + + E + + KPF ++T
Sbjct: 274 FTMMELYMAYADYKD-LIELTESLFRTLAQDILGKTEVTYGDVTLDFG---KPFEKLTMR 329
Query: 287 EALEILS-----------DLGKEIPWGEDIDTEGEKLLGKYMLE--NEGAELY-----FI 328
EA++ D K I I E LG+ + E E AE + FI
Sbjct: 330 EAIKKYRPETDMADLDNFDSAKAIAESIGIHVEKSWGLGRIVTEIFEEVAEAHLIQPTFI 389
Query: 329 YRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSG----GQREHRHDILVEQIREKGL 384
YP+E P + + PE+ F+ G EI +G E + ++Q+ K
Sbjct: 390 TEYPAEVSPL-ARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAQRFLDQVAAKDA 448
Query: 385 NPESFEFY----LRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDR 433
+ FY + A E+G+PP G G+G +R++M + IR+VILFP R
Sbjct: 449 GDDEAMFYDEDYVTALEHGLPPTAGLGIGIDRMVMLFTNSHTIRDVILFPAMR 501
>emb|CAC11748.1| (AL445064) asparagine--tRNA ligase related protein [Thermoplasma
acidophilum]
Length = 329
Score = 131 bits (326), Expect = 2e-29
Identities = 96/324 (29%), Positives = 161/324 (49%), Gaps = 29/324 (8%)
Query: 116 ELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEG-GTE 174
E++T ++ L P + K++SS+ T EF + GFIE+ P II+ T+
Sbjct: 20 EINTLIEEISEHLEKPELYHALKVQSSIRSITSEFLKERGFIEV-PPVIISVLTDPLNHP 78
Query: 175 LFP--LKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHN---TTRHLNEAWS 229
+F + Y+ L +S ++ + +++ D++F P R EE + T RHL E
Sbjct: 79 VFDPTIDYYGYKYSLTKS-MIFHKHLLTKHFDRIFTFSPNIRLEEEDKVKTGRHLAEFTQ 137
Query: 230 IDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEAL 289
+D EM S +EVM L E +I+ + ++ +NE++LK +L P KPF RI Y +A
Sbjct: 138 LDLEMKGA-SRDEVMSLGEDMIIDLFKKIKRSNEEDLKFFGRDLRIPSKPFKRIAYLDAY 196
Query: 290 EILSDLGKEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEV 349
+ +GED + ++L +E E ++I P E + FY + +P +
Sbjct: 197 K---------QYGEDFE---------HILSSEMKEPFWIIDIPLEKREFYDREDPSRPGI 238
Query: 350 CKAFDLEY-RGV-EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFG 407
DL Y G E SGG+RE+ ++++I KG E F++Y+ + G+ P GFG
Sbjct: 239 LVDMDLIYPEGFGEALSGGEREYELSRIIDRIHRKGQTEEQFKWYIEFAKEGLMPSAGFG 298
Query: 408 LGAERLIMRMLDIGNIREVILFPR 431
+G ERL + + I + FP+
Sbjct: 299 IGIERLTRFICGLERIEDAHPFPK 322
>sp|Q9RHV9|SYK_BACST LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|6681368|dbj|BAA88691.1| (AB012100) lysyl-tRNA
synthetase [Bacillus stearothermophilus]
Length = 494
Score = 131 bits (325), Expect = 2e-29
Identities = 127/478 (26%), Positives = 224/478 (46%), Gaps = 62/478 (12%)
Query: 3 RTHYSSEI--------TEELNGKKVKVA--GWVQEVKDLGGIKFIWIRDREGIVQVTAPK 52
RTH + E+ EEL ++++VA G + + +G F I+D G +Q+ +
Sbjct: 34 RTHKAEELFELYGDLSKEELEEQQIEVAVAGRIMTKRGMGKAGFAHIQDVTGQIQIYVRQ 93
Query: 53 KKVPQEIFKLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGK 112
V ++ ++L + D++ V G + T +L ++ E ++KA PLP G
Sbjct: 94 DDVGEQQYELFKISDLGDIVGVRGTMFKTKVGELSIKV--SSYEFLTKALRPLPEKYHGL 151
Query: 113 VKAELDTRLDNRFMDL-RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEG 171
+++ R R++DL NP F RS + ++ R + G++E+ TP + A A G
Sbjct: 152 --KDIEQRYRQRYLDLIMNPESKKTFITRSLIIQSMRRYLDSHGYLEVETPMMHAVA--G 207
Query: 172 GTELFPLKYFEN----DAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEA 227
G P N ++ + +L+ + ++ GL+KV+EIG +FR E +TRH E
Sbjct: 208 GAAARPFITHHNALDMTLYMRIAIELHLKRLIVGGLEKVYEIGRVFR-NEGISTRHNPEF 266
Query: 228 WSIDAEMAFIESEEEVMDLLERLILYV---------INYVRENNEKELKILEFELNEPKK 278
++ A+ + + +M L E LI ++ I Y + + + + K
Sbjct: 267 TMLELYEAYADFRD-IMKLTENLIAHIATEVLGTTKIQYGEHLVDLTPEWRRLHMVDAIK 325
Query: 279 PFPRITY------DEALEILSDLGKEIP----WGEDIDTEGEKLLGKYMLENEGAELYFI 328
+ + + +EA E+ + G E+ +G ++ E+ +E++ + FI
Sbjct: 326 EYVGVDFWRQMSDEEARELAKEHGVEVAPHMTFGHIVNEFFEQ-----KVEDKLIQPTFI 380
Query: 329 YRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSG--------GQREHRHDILVEQIR 380
Y +P E P K D P F+L G E ++ QR+ + L E R
Sbjct: 381 YGHPVEISPL-AKKNPDDPRFTDRFELFIVGREHANAFTELNDPIDQRQRFEEQLKE--R 437
Query: 381 EKGLNPESFEF---YLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRRR 435
E+G N E+ E +L A EYGMPP GG G+G +RL+M + + +IR+V+LFP+ R +
Sbjct: 438 EQG-NDEAHEMDEDFLEALEYGMPPTGGLGIGVDRLVMLLTNSPSIRDVLLFPQMRHK 494
>pir||F81831 aspartate--tRNA ligase (EC 6.1.1.12) NMA2019 [imported] - Neisseria
meningitidis (group A strain Z2491)
>gi|7380648|emb|CAB85238.1| (AL162757) aspartyl-tRNA
synthetase [Neisseria meningitidis Z2491]
Length = 602
Score = 131 bits (325), Expect = 2e-29
Identities = 97/297 (32%), Positives = 148/297 (49%), Gaps = 29/297 (9%)
Query: 2 LRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFK 61
+RT+Y I+E+ + V V GWV +D GG+ FI +RDREGIVQV E F
Sbjct: 1 MRTNYCGLISEQYLDQTVTVKGWVHRRRDHGGVIFIDLRDREGIVQVVIDPD--TPEAFA 58
Query: 62 LIPKLNSEDVIVVEGIVNFTPKAKLG-------FEIIPEKLEVISKAKTPLPLDPTGKVK 114
+E V+ + G V P+ EI+ +++EV++ A TP P +
Sbjct: 59 AADSARNEYVLSITGRVRNRPEGTTNDKMISGKIEILAKEIEVLNAAATP-PFQIDDENI 117
Query: 115 AELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTE 174
+E + RL NR +DLR P + ++R V R + +GFI+I TP + + EG +
Sbjct: 118 SE-NVRLTNRVIDLRRPVMQRNLRLRYQVAMGVRRYLDAQGFIDIETPMLTRSTPEGARD 176
Query: 175 -LFPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDA 232
L P + + F L QSPQL+KQ++M G D+ ++I FR E+ R E ID
Sbjct: 177 YLVPSRVHPGEFFALPQSPQLFKQLLMVAGFDRYYQITKCFRDEDLRADRQ-PEFTQIDL 235
Query: 233 EMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEAL 289
E +F+ +E+E+MD+ E + V L +L + FPR+ Y EA+
Sbjct: 236 ETSFL-NEDEIMDITEGMAKQVFK----------DALGVDLGD----FPRMPYSEAM 277
>pir||JC7205 lysine-tRNA ligase (AMP forming) (EC 6.1.1.6) - Bacillus
stearothermophilus
Length = 493
Score = 131 bits (325), Expect = 2e-29
Identities = 127/478 (26%), Positives = 224/478 (46%), Gaps = 62/478 (12%)
Query: 3 RTHYSSEI--------TEELNGKKVKVA--GWVQEVKDLGGIKFIWIRDREGIVQVTAPK 52
RTH + E+ EEL ++++VA G + + +G F I+D G +Q+ +
Sbjct: 33 RTHKAEELFELYGDLSKEELEEQQIEVAVAGRIMTKRGMGKAGFAHIQDVTGQIQIYVRQ 92
Query: 53 KKVPQEIFKLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGK 112
V ++ ++L + D++ V G + T +L ++ E ++KA PLP G
Sbjct: 93 DDVGEQQYELFKISDLGDIVGVRGTMFKTKVGELSIKV--SSYEFLTKALRPLPEKYHGL 150
Query: 113 VKAELDTRLDNRFMDL-RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEG 171
+++ R R++DL NP F RS + ++ R + G++E+ TP + A A G
Sbjct: 151 --KDIEQRYRQRYLDLIMNPESKKTFITRSLIIQSMRRYLDSHGYLEVETPMMHAVA--G 206
Query: 172 GTELFPLKYFEN----DAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEA 227
G P N ++ + +L+ + ++ GL+KV+EIG +FR E +TRH E
Sbjct: 207 GAAARPFITHHNALDMTLYMRIAIELHLKRLIVGGLEKVYEIGRVFR-NEGISTRHNPEF 265
Query: 228 WSIDAEMAFIESEEEVMDLLERLILYV---------INYVRENNEKELKILEFELNEPKK 278
++ A+ + + +M L E LI ++ I Y + + + + K
Sbjct: 266 TMLELYEAYADFRD-IMKLTENLIAHIATEVLGTTKIQYGEHLVDLTPEWRRLHMVDAIK 324
Query: 279 PFPRITY------DEALEILSDLGKEIP----WGEDIDTEGEKLLGKYMLENEGAELYFI 328
+ + + +EA E+ + G E+ +G ++ E+ +E++ + FI
Sbjct: 325 EYVGVDFWRQMSDEEARELAKEHGVEVAPHMTFGHIVNEFFEQ-----KVEDKLIQPTFI 379
Query: 329 YRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSG--------GQREHRHDILVEQIR 380
Y +P E P K D P F+L G E ++ QR+ + L E R
Sbjct: 380 YGHPVEISPL-AKKNPDDPRFTDRFELFIVGREHANAFTELNDPIDQRQRFEEQLKE--R 436
Query: 381 EKGLNPESFEF---YLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRRR 435
E+G N E+ E +L A EYGMPP GG G+G +RL+M + + +IR+V+LFP+ R +
Sbjct: 437 EQG-NDEAHEMDEDFLEALEYGMPPTGGLGIGVDRLVMLLTNSPSIRDVLLFPQMRHK 493
>emb|CAC08476.1| (AL392189) aspartyl-tRNA synthetase [Streptomyces coelicolor]
Length = 587
Score = 130 bits (324), Expect = 3e-29
Identities = 92/296 (31%), Positives = 148/296 (49%), Gaps = 26/296 (8%)
Query: 3 RTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKL 62
R+H E+ G V+++GW+ +DLGGI FI +RD GI Q+ A + E ++
Sbjct: 5 RSHTCGELRSSDVGTDVRLSGWLHNRRDLGGILFIDLRDHYGITQLVA---RPGTEAYEA 61
Query: 63 IPKLNSEDVIVVEGIV------NFTPKAKLG-FEIIPEKLEVISKAKTPLPLDPTGKVKA 115
+ KL E + V+G V N P G E+ ++E++ A+ PLP +
Sbjct: 62 LDKLTKESTVRVDGKVVSRGADNINPDLPTGEVEVEVGEVELLGAAQ-PLPFTINTEDGV 120
Query: 116 ELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTEL 175
+ RL+ RF+DLR R+ +R+SV + R GF E+ TP + AT+ EG +
Sbjct: 121 NEERRLEYRFLDLRRERMHRNIMLRTSVISSIRSKMVALGFNEMATPILTATSPEGARDF 180
Query: 176 FPLKYFENDAFLA--QSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAE 233
F A Q+PQ +KQ++M +G D+ F+I P FR E+ R E + +D E
Sbjct: 181 VVPSRLHAGRFYALPQAPQQFKQLLMISGFDRYFQIAPCFRDEDARADRSPGEFYQLDVE 240
Query: 234 MAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEAL 289
M+F+E +E+V +E+L+ + + N + + PFPRI + EA+
Sbjct: 241 MSFVE-QEDVFRPIEQLMTEL--FEEFGNGRHV----------TSPFPRIPFREAM 283
>sp|P37477|SYK_BACSU LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|2127132|pir||S66111 lysine--tRNA ligase (EC 6.1.1.6)
lysS - Bacillus subtilis >gi|467470|dbj|BAA05316.1|
(D26185) lysyl-tRNA thynthetase [Bacillus subtilis]
>gi|2632349|emb|CAB11858.1| (Z99104) lysyl-tRNA
synthetase [Bacillus subtilis]
Length = 499
Score = 130 bits (323), Expect = 4e-29
Identities = 130/475 (27%), Positives = 220/475 (45%), Gaps = 56/475 (11%)
Query: 3 RTHYSSEIT--------EELNGKKVKV--AGWVQEVKDLGGIKFIWIRDREGIVQVTAPK 52
RTH S E+ EEL K ++V AG + + G F ++D EG +Q+ K
Sbjct: 39 RTHQSQEVISAYQDLTKEELEEKAIEVTIAGRMMTKRGKGKAGFAHLQDLEGQIQIYVRK 98
Query: 53 KKVPQEIFKLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGK 112
V + +++ + D+I V G V T +L + E+++KA PLP D
Sbjct: 99 DSVGDDQYEIFKSSDLGDLIGVTGKVFKTNVGELSVKAT--SFELLTKALRPLP-DKYHG 155
Query: 113 VKAELDTRLDNRFMDLR-NPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEG 171
+K +++ R R++DL NP F RS + +A R + G++E+ TP + + G
Sbjct: 156 LK-DVEQRYRQRYLDLIVNPDSKHTFITRSKIIQAMRRYLDDHGYLEVETPTM--HSIPG 212
Query: 172 GTELFPLKYFEN----DAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEA 227
G P N ++ + +L+ + ++ GL+KV+EIG +FR E +TRH E
Sbjct: 213 GASARPFITHHNALDIPLYMRIAIELHLKRLIVGGLEKVYEIGRVFR-NEGVSTRHNPEF 271
Query: 228 WSIDAEMAFIESEEEVMDLLERLILYV---------INYVRENNEKELKILEFELNEPKK 278
I+ A+ + ++ +M L E L+ ++ I Y E + + + + + K
Sbjct: 272 TMIELYEAYADYKD-IMSLTENLVAHIAQEVLGTTTIQYGEEQIDLKPEWKRIHMVDAVK 330
Query: 279 PFPRITYDEALEILSDLGKEIPWGEDIDTEGEKLLGKYM-------LENEGAELYFIYRY 331
+ + E E+ + +E +++ + +G + +E + FIY +
Sbjct: 331 EATGVDFWE--EVTVEQAREYAKEHEVEIKDSMTVGHIINEFFEQKIEETLIQPTFIYGH 388
Query: 332 PSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSG--------GQREHRHDILVEQIREKG 383
P E P ED P F+L G E ++ QRE L E RE G
Sbjct: 389 PVEISPLAKKNPED-PRFTDRFELFIVGREHANAFTELNDPIDQRERFEAQLKE--REAG 445
Query: 384 LNPESF---EFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRRR 435
N E+ E ++ A EYGMPP GG G+G +RL+M + + +IR+V+LFP+ R+R
Sbjct: 446 -NDEAHLMDEDFVEALEYGMPPTGGLGIGIDRLVMLLTNAPSIRDVLLFPQMRQR 499
>sp|Q53638|SYK_STAAU LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|567884|gb|AAA53114.1| (L36472) lysyl-tRNA synthetase
[Staphylococcus aureus]
Length = 495
Score = 130 bits (323), Expect = 4e-29
Identities = 118/457 (25%), Positives = 213/457 (45%), Gaps = 42/457 (9%)
Query: 9 EITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNS 68
E+ E+ V +AG + + G F ++D G +Q+ K +V + F L +
Sbjct: 51 ELVEKEADSHVAIAGRLMTKRGKGKAGFAHVQDLAGQIQIYVRKDQVGDDEFDLWKNADL 110
Query: 69 EDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDL 128
D++ VEG++ T +L + +K +++K+ PLP G +++ R R++DL
Sbjct: 111 GDIVGVEGVMFKTNTGELSVKA--KKFTLLTKSLRPLPDKFHGL--QDIEQRYRQRYLDL 166
Query: 129 -RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDA-- 185
N F RS + + R + +GF+E+ TP + A F + DA
Sbjct: 167 ITNEDSTRTFINRSKIIQEMRNYLNNKGFLEVETPMMHQIAGGAAARPFVTHHNALDATL 226
Query: 186 FLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMD 245
++ + +L+ + ++ GL+KV+EIG +FR E +TRH E I+ A+ + + +MD
Sbjct: 227 YMRIAIELHLKRLIVGGLEKVYEIGRVFR-NEGVSTRHNPEFTMIELYEAYADYHD-IMD 284
Query: 246 LLERLILYVINYVR--------------ENNEKELKILEFELNEPKKPFPRITYDEALEI 291
L E ++ ++ N V E+ L I++ F + DE +
Sbjct: 285 LTESMVRHIANEVLGSAKVQYNGETIDLESAWTRLHIVDAVKEATGVDFYEVKSDEERKA 344
Query: 292 LS-----DLGKEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDK 346
L+ ++ + +G ++ E+ + + +++ FIY +P+E P ED
Sbjct: 345 LAKEHGIEIKDTMKYGHILNEFFEQKVEETLIQPT-----FIYGHPTEISPLAKKNPED- 398
Query: 347 PEVCKAFDLEYRG-------VEISSGGQREHRHDI-LVEQIREKGLNPESFEFYLRAFEY 398
P F+L G E++ ++ R + LVE+ + E E Y+ A EY
Sbjct: 399 PRFTDRFELFIVGREHANRFTELNDPIDQKGRFEAQLVEKAQGNDEAHEMDEDYIEALEY 458
Query: 399 GMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRRR 435
GMPP GG G+G +RL+M + D +IR+V+LFP R++
Sbjct: 459 GMPPTGGLGIGIDRLVMLLTDSPSIRDVLLFPYMRQK 495
>pir||S77851 probable aspartate--tRNA ligase (EC 6.1.1.12) - Mycoplasma
capricolum
Length = 524
Score = 129 bits (321), Expect = 6e-29
Identities = 98/301 (32%), Positives = 155/301 (50%), Gaps = 34/301 (11%)
Query: 1 MLRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF 60
M RTH E+T + +KV + GWV++++ LG + FI ++DR GI Q+ + QE
Sbjct: 1 MKRTHTCGELTLQNVDQKVILQGWVKKIRKLGAMVFIDLKDRYGITQLV-----IEQENI 55
Query: 61 KLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISK--------AKTPLPLDPTGK 112
LI L +E VI + GIV + + E+I ++EVI K TP L+
Sbjct: 56 NLINNLKNEYVIEISGIV--VKRKSVNKELITGEIEVIVKDLLVINKSELTPFVLE--ND 111
Query: 113 VKAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGG 172
V DTRL R++DLR + + IR+ + R + F+E+ TP + EG
Sbjct: 112 VNVNEDTRLTYRYLDLRRQVMQNNLIIRAKINHIIRNYLTDLNFLEVETPYFAKSTPEGA 171
Query: 173 TE-LFPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSI 230
L P + +N + L QSPQL+KQ++M +G+D+ ++I FR E+ R E +
Sbjct: 172 RHFLVPSRLNKNKFYALPQSPQLFKQLLMISGIDRYYQIVRCFRDEDLRIDRQ-PEFTQL 230
Query: 231 DAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALE 290
D EM+F S E+VM + E LI ++ KE+K E K+P R++Y +A++
Sbjct: 231 DLEMSFATS-EDVMQISESLIKKIL--------KEVKNFEI-----KEPLLRLSYKDAID 276
Query: 291 I 291
+
Sbjct: 277 L 277
>sp|Q9X231|SYK_THEMA LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|7437571|pir||C72221 lysine--tRNA ligase (EC 6.1.1.6)
- Thermotoga maritima (strain MSB8)
>gi|4982282|gb|AAD36772.1|AE001810_11 (AE001810)
lysyl-tRNA synthetase [Thermotoga maritima]
Length = 502
Score = 128 bits (318), Expect = 1e-28
Identities = 130/445 (29%), Positives = 204/445 (45%), Gaps = 36/445 (8%)
Query: 12 EELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPK-LNSED 70
E L +K+ AG V ++ G F ++D G +Q V +E L + + D
Sbjct: 48 EVLESEKLSFAGRVMSIRHHGKTAFFHMKDDTGRIQAYIKADSVGKEKMDLFKRHVKIGD 107
Query: 71 VIVVEGIVNFTPKAKLG-FEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLR 129
+ V G F K+K G I ++ ++SKA PLP G E+ R R+++L
Sbjct: 108 FVGVRG---FPFKSKTGELTIYVQEYTLLSKALRPLPEKWHGIKDKEIIYR--QRYLELI 162
Query: 130 -NPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFP----LKYFEND 184
N + FK R R REF GFIE+ TP I GG E P L F+ D
Sbjct: 163 VNDEAIERFKKRFKAVRVIREFLNSRGFIEVETP--ILHYVTGGAEARPFVTHLNVFDID 220
Query: 185 AFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVM 244
+L +P+LY + ++ G +K++EIG FR E + +H E SI+ A+ + + +M
Sbjct: 221 MYLRIAPELYLKRLIVGGFEKIYEIGKNFR-NEGISYKHSPEFTSIEIYQAYADYND-MM 278
Query: 245 DLLERLILYVINYVRENNEKELKILEFELNEP-KKPFPRITYDEAL--EILSD-----LG 296
DL E LI+ V+ + + E + P K+ R E L +IL D L
Sbjct: 279 DLTEELIVEVVKRTCGTLKISYQGKEIDFTPPWKRVRMRDFLKEKLGVDILEDPDEVLLK 338
Query: 297 KEIPWGEDIDTEGEK-LLGKY--MLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAF 353
K G +++ + L+ K ++E E FI +P P ++ + P + + F
Sbjct: 339 KLEEHGVELEIKNRAHLIDKLRDLVEEELVNPTFIIDHPVVISPL-AKRHREDPRLTERF 397
Query: 354 DLEYRGVEISSGGQREH----RHDILVEQIREKGLNPESFEF----YLRAFEYGMPPHGG 405
+L G EI++ + ++ +EQ + + E ++RA EYGMPP GG
Sbjct: 398 ELIIFGREIANAFSELNDPVDQYQRFLEQAKMREEGDEEAHMMDLDFVRALEYGMPPTGG 457
Query: 406 FGLGAERLIMRMLDIGNIREVILFP 430
G+G +RL M + D IR+VI FP
Sbjct: 458 LGIGLDRLFMFITDSPTIRDVIPFP 482
>pir||E81660 aspartyl-tRNA synthetase TC0829 [imported] - Chlamydia muridarum
(strain Nigg) >gi|7190856|gb|AAF39629.1| (AE002349)
aspartyl-tRNA synthetase [Chlamydia muridarum]
Length = 582
Score = 128 bits (318), Expect = 1e-28
Identities = 97/304 (31%), Positives = 161/304 (52%), Gaps = 40/304 (13%)
Query: 3 RTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKL 62
RTH +E++ G+ V+++GWV ++ GG+ FI +RDR GI Q+ +++ P E+ +L
Sbjct: 4 RTHKCNELSLNHVGEHVRLSGWVHRYRNHGGVVFIDLRDRFGITQIVCRQEENP-ELHRL 62
Query: 63 IPKLNSEDVIVVEGIVNFTPKAKLG-----------FEIIPEKLEVISKAKTPLPLDPTG 111
+ ++ SE V+ VEG+V A+LG E+ LEV+S+A+ LP +
Sbjct: 63 MDQVRSEWVLCVEGLV----CARLGGMENPNLVTGSIEVEVSHLEVLSRAQN-LPFSISD 117
Query: 112 K-VKAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATE 170
+ + + RL R++D+R ++ R V A R++ ++GF E+ TP + + E
Sbjct: 118 EHINVNEELRLTYRYLDMRRGDIVDRLMCRHKVMLACRQYLDEQGFTEVVTPVLGKSTPE 177
Query: 171 GGTE-LFPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAW 228
G + L P + + + + L QSPQL+KQ++M GLD+ F+I FR E+ R E
Sbjct: 178 GARDYLVPSRIYPGNFYALPQSPQLFKQILMVGGLDRYFQIATCFRDEDLRADRQ-PEFS 236
Query: 229 SIDAEMAFIESEEEVMDLLERLI--LYVINYVRENNEKELKILEFELNEPKKPFPRITYD 286
ID EM+F E++ ++E L+ L+ + + EL I PF R+TY
Sbjct: 237 QIDMEMSF-GGPEDLFPIVEELVTRLFAVKGI------ELSI----------PFQRMTYQ 279
Query: 287 EALE 290
EA E
Sbjct: 280 EAKE 283
>sp|Q43990|SYK_ACICA LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|1359473|emb|CAA86924.1| (Z46863) lysyl-tRNA-synthase
[Acinetobacter sp. ADP1]
Length = 509
Score = 127 bits (317), Expect = 2e-28
Identities = 128/479 (26%), Positives = 212/479 (43%), Gaps = 65/479 (13%)
Query: 3 RTHYSSEITEELNG-----------KKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAP 51
R HY++++ E+ VKVAG V L F+ I+D G +Q+
Sbjct: 48 REHYAADLQEQFKDIDKAQIEGSDKTYVKVAGRVM----LNRGSFMVIQDMTGRIQLYVD 103
Query: 52 KKKVPQEIFKLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTG 111
+K +P + + I L+ D+I EG + + K L + E E+++K+ PLP G
Sbjct: 104 RKGLPADTLETIKSLDLGDIIAAEGYIGRSGKGDLYVHL--EGFELLTKSLRPLPDKFHG 161
Query: 112 KVKAELDTRLDNRFMDLR-NPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATE 170
E R R++DL N F+IR+ V R F + F+E+ TP +
Sbjct: 162 LTDTEAKYR--KRYLDLIVNEETRKTFEIRAQVVAGIRAFLTNQRFMEVETPMM--HVIP 217
Query: 171 GGTELFPLKYFEN----DAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNE 226
GG P N + +L +P+LY + ++ G ++VFEI FR E +TRH E
Sbjct: 218 GGASAQPFVTHHNALDMELYLRIAPELYLKRLVVGGFERVFEINRNFR-NEGVSTRHNPE 276
Query: 227 AWSIDAEMAFIESEEEVM---DLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRI 283
I+ A+ + ++ + ++LE+L L ++ E+ K PF +I
Sbjct: 277 FTMIEFYQAYADYKDLMQLTENMLEKLALDILGTTDVPYGDEVYSF-------KGPFKKI 329
Query: 284 T-YDEALEILSDLGKE--------IPWGEDIDTEGEKL---LGKYM-------LENEGAE 324
+ +D LE D E + +D+ E K LGK +E + +
Sbjct: 330 SMFDAILEHNPDFTPENVNDREFLAKFTQDVLKEQVKPGFGLGKLQTIVFEETVETKLRQ 389
Query: 325 LYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSGGQREH----RHDILVEQIR 380
FI YP+E P + +D P + F+ G E+++G + + + Q+
Sbjct: 390 PTFITEYPAETSPL-ARRNDDNPHITDRFEFFIGGRELANGFSELNDPIDQAERFQAQVA 448
Query: 381 EKGLNPESFEFY----LRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRRR 435
EK + Y + A EYG+PP G G+G +RL+M + +IR+V+LFP RR+
Sbjct: 449 EKDAGDDEAMHYDADFIEALEYGLPPTAGQGIGIDRLVMIFANAPSIRDVLLFPHMRRK 507
>sp|P43817|SYD_HAEIN ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|1073870|pir||E64061 aspartate--tRNA ligase (EC
6.1.1.12) - Haemophilus influenzae (strain Rd KW20)
>gi|1573287|gb|AAC21981.1| (U32717) aspartyl-tRNA
synthetase (aspS) [Haemophilus influenzae Rd]
Length = 588
Score = 127 bits (316), Expect = 2e-28
Identities = 86/259 (33%), Positives = 134/259 (51%), Gaps = 14/259 (5%)
Query: 1 MLRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF 60
M+RTHY + G+ V ++GWV +DLGG+ FI +RDR+GIVQV K Q+
Sbjct: 1 MMRTHYCGALNRNNIGQDVTLSGWVHRRRDLGGLIFIDMRDRDGIVQVCFDPKY--QDAL 58
Query: 61 KLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISK------AKTPLPLDPTGKVK 114
L +E I ++G V P ++ + ++EV++K A LPLD
Sbjct: 59 TAAAGLRNEFCIQIKGEVIARPDNQINKNMATGEVEVLAKELRIYNASDVLPLDFNQNNT 118
Query: 115 AELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTE 174
E RL R++DLR P + K R+ + R F GF++I TP + EG +
Sbjct: 119 EE--QRLKYRYLDLRRPEMAQRLKTRAKITSFVRRFMDDNGFLDIETPMLTKATPEGARD 176
Query: 175 -LFPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDA 232
L P + + + L QSPQL+KQ++M +G D+ ++I FR E+ R E ID
Sbjct: 177 YLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQ-PEFTQIDV 235
Query: 233 EMAFIESEEEVMDLLERLI 251
E +F+ + EV +++ER++
Sbjct: 236 ETSFL-TAPEVREIMERMV 253
>sp|Q9ZE17|SYD_RICPR ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|7437607|pir||F71724 aspartate--tRNA ligase (EC
6.1.1.12) - Rickettsia prowazekii
>gi|3860712|emb|CAA14613.1| (AJ235270) ASPARAGINYL-TRNA
SYNTHETASE (aspS) [Rickettsia prowazekii]
Length = 605
Score = 126 bits (313), Expect = 6e-28
Identities = 86/295 (29%), Positives = 148/295 (50%), Gaps = 23/295 (7%)
Query: 3 RTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKL 62
RTH +E+ G++VK++GWV +D G + FI +RD GI Q+ + Q++
Sbjct: 5 RTHNCNELQLSNVGQEVKLSGWVHRRRDHGNLVFIDLRDHYGITQIVFTDQN--QQLMYD 62
Query: 63 IPKLNSEDVIVVEGIV------NFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAE 116
+L E VI V G V K G+ + ++ A +PLP + +A
Sbjct: 63 ASRLCYESVITVSGTVVARSLDTINNKLPTGYVEVLAMECIVESASSPLPFVINNEKEAP 122
Query: 117 LDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTE-L 175
++RL +RF+DLR ++ + +RS V R GF E+ TP + +++ EG + L
Sbjct: 123 EESRLKHRFLDLRREKLHNNIILRSQVIAHIRHLMIARGFTELQTPILTSSSPEGARDFL 182
Query: 176 FPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEM 234
P + + L Q+PQ +KQ++M G D+ F+I P FR E+ R E + +D EM
Sbjct: 183 VPSRIHPGKFYALPQAPQQFKQLLMVAGFDRYFQIAPCFRDEDARADRSPGEFYQLDLEM 242
Query: 235 AFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEAL 289
+F+ ++E++ + +E +LY + + + N+ PF RI Y+E++
Sbjct: 243 SFV-TQEDIFNTIEP-VLYDL-FTKFTNK----------TVSNTPFVRIPYNESM 284
>gb|AAF46510.1| (AE003447) CG12141 gene product [Drosophila melanogaster]
Length = 572
Score = 126 bits (313), Expect = 6e-28
Identities = 133/464 (28%), Positives = 209/464 (44%), Gaps = 56/464 (12%)
Query: 12 EELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGI-VQVTAPKKKVPQEI-FKL-IPKLNS 68
E L K+ VAG V +++ G + EG+ VQV A K E F++ KL
Sbjct: 100 ETLENVKLSVAGRVHAIRESGAKLIFYDLRGEGVKVQVMASAKSYKSEADFEIDTSKLRR 159
Query: 69 EDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDL 128
D+I V G T K +L ++P +++++S LP G E TR R++DL
Sbjct: 160 GDIIGVVGHPGKTKKGELS--VMPSEIKLLSPCLHMLPHLHFGLKDKE--TRYRQRYLDL 215
Query: 129 -RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDA-- 185
N V F+IR+ + R+F + GF+EI TP + A GG P ND
Sbjct: 216 ILNNNVREKFQIRAKIISYVRQFLDRLGFLEIETPMMNMIA--GGATAKPFVTHHNDLKM 273
Query: 186 --FLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEV 243
F+ +P+LY +M++ GLD+V+EIG FR E + T H E + + MA+ + + +
Sbjct: 274 DLFMRIAPELYHKMLVVGGLDRVYEIGRQFRNEGIDLT-HNPEFTTCEFYMAYADYAD-I 331
Query: 244 MDLLERLILYVINYVR------------ENNEKEL------------KILEFELNEPKKP 279
MD+ E+L+ ++ +R E E+EL K LE +L
Sbjct: 332 MDITEQLVSGMVKAIRGSYKVIYHPEGPEGPEQELDFTPPFKRVSMIKTLEEKLQVKFPA 391
Query: 280 FPRITYDEALEILSDLGK----EIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEA 335
E + LS L E P +KL+G++ +E FI +P
Sbjct: 392 ADTFNSPETNQFLSQLCAKHQVECPAPRTTARLLDKLVGEF-IEEFCVNPTFICEHPQIM 450
Query: 336 KPFYIMKYEDK-PEVCKAFDLEYRGVEISSGGQREH----RHDILVEQIREKGLNPESFE 390
P + KY P + + F+L EI + + + + +Q +K + +
Sbjct: 451 SP--LAKYHRSIPGLTERFELFVAKKEICNAYTELNDPVVQRERFEQQASDKAAGDDEAQ 508
Query: 391 F----YLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFP 430
+ + EYG+PP GGFG+G +RL M + D NI+EV+LFP
Sbjct: 509 LVDENFCTSLEYGLPPTGGFGMGIDRLAMFLTDSNNIKEVLLFP 552
>pir||B81858 lysine--tRNA ligase (EC 6.1.1.6) NMA1638 [imported] - Neisseria
meningitidis (group A strain Z2491)
>gi|7380280|emb|CAB84866.1| (AL162756) lysyl-tRNA
synthetase [Neisseria meningitidis Z2491]
Length = 503
Score = 126 bits (313), Expect = 6e-28
Identities = 129/465 (27%), Positives = 210/465 (44%), Gaps = 45/465 (9%)
Query: 2 LRTHYSSEITEELN--GKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEI 59
L Y EEL+ G VKVAG + + +G F I+D G +Q+ K V QE+
Sbjct: 49 LHAQYGEIGKEELDPQGIPVKVAGRMMLKRQMGKASFATIQDVSGQIQLYLNNKGVSQEV 108
Query: 60 FKLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDT 119
+ D++ EG + T +L + + ++SK+ PLP G ++ +T
Sbjct: 109 LDDFNHWDLGDIVGAEGTLFKTNHGELTVRV--SGIRLLSKSLRPLPDKHKGL--SDQET 164
Query: 120 RLDNRFMDL-RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPL 178
+ R++DL N + F RS + ++ R F E ++E+ TP + GG P
Sbjct: 165 KYRQRYVDLIANEESRNTFIKRSQIIQSVRNFMVGEHYLEVETPMM--HPIPGGATAKPF 222
Query: 179 KYFEN----DAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEM 234
N +L +P+LY + ++ GL++VFEI FR E + RH E I+
Sbjct: 223 VTHHNALDIPLYLRIAPELYLKRLVVGGLERVFEINRSFR-NEGMSVRHNPEFTMIEFYE 281
Query: 235 AFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALE---- 290
AF + E +M + E +I + V E +L + PF R+T EA++
Sbjct: 282 AFSDYER-MMQMAEDIIRNASHTVNGTANITYNGKEVDL---ESPFERLTILEAIKKYNP 337
Query: 291 -ILSDLGKEIPW-GEDIDTEGEKL-----LGKYML-------ENEGAELYFIYRYPSEAK 336
+ + W ++I GE L +G L E + FI YP E
Sbjct: 338 HYTDEQLNDAEWLKKEIVKHGESLPPSPGIGSLQLALFEGCAEGKLWNPTFIVDYPVEVS 397
Query: 337 PFYIMKYEDKPEVCKAFDLEYRGVEISSG----GQREHRHDILVEQIREKGL-NPESFEF 391
P + K + + F+L G E+++G E + + Q+ +K + E+ +
Sbjct: 398 PL-ARASDTKQGLTERFELFVVGRELANGYSELNDPEDQAERFKAQVAQKDAGDDEAMHY 456
Query: 392 ---YLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDR 433
Y+RA E+G+PP GG G+G +RL+M + D IR+VILFP+ R
Sbjct: 457 DADYIRAMEFGLPPTGGCGIGIDRLVMLLTDSQTIRDVILFPQMR 501
>sp|Q49158|SYK_MYCFE LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|1263074|gb|AAC43988.1| (U50826) lysyl-tRNA
synthetase [Mycoplasma fermentans]
Length = 488
Score = 125 bits (310), Expect = 1e-27
Identities = 125/463 (26%), Positives = 226/463 (47%), Gaps = 48/463 (10%)
Query: 2 LRTHYSSEITEELNGKKVK--VAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEI 59
L Y EEL KKVK ++G + + F+ ++DR+G +QV KK+ P E+
Sbjct: 41 LNKKYGQFAREELEAKKVKKNISGRLITARG----PFLVLKDRKGTIQVYFNKKENP-EL 95
Query: 60 FKLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDT 119
K++ + D++ V G++ T ++ + + +++++KA PLP G E
Sbjct: 96 TKIVETFDLGDILWVRGLLMKTHTCEM--TVRAQDIQLLTKALKPLPDKFHGLTDTE--E 151
Query: 120 RLDNRFMDL-RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPL 178
R +R++DL NP + F +R+ + + R++F K ++E TP + + + F
Sbjct: 152 RYRHRYLDLITNPESRNTFIMRTKIVQWIRDYFNKLDYLEAETPFLHDYLSGAAAKPFTT 211
Query: 179 KY--FENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAF 236
+ D L + ++ + ++ G ++V+E+G IFR E ++TT H E +I+ A+
Sbjct: 212 HHNSLNQDFVLRIATEIPLKKLVVGGFERVYEMGRIFRNEGYDTT-HNPEFTTIEFYEAY 270
Query: 237 IESEEEVMDLLERLIL----------YVINYVRENNEKELK---ILEFELNEPKKPFPRI 283
+ E +M+ E LI +V N V + K K +++ + K F +I
Sbjct: 271 -SNVEGMMNRTETLIKELCKKIGKSKFVTNGVEVDLSKPFKRVNMIDEVSKKTGKNFRKI 329
Query: 284 TYDEALEILSDLGKEIPWGEDIDTEGEKLLGKY--MLENEGAELYFIYRYPSEAKPFYIM 341
T +EA+E+ +I E T G + Y ++E + F+Y +P E P +
Sbjct: 330 TLEEAIEVAKAYKIKI---EKFFTIGHIINALYEELVEPTLIQPTFLYGHPIEISP--LS 384
Query: 342 KYEDKPEVCKAFDL-----EYRGV--EISSGGQREHRHDILVEQIREKGLNPESFEF--- 391
D P + +L EY + E+S + R + +E+ + KG N E+ +
Sbjct: 385 AKSDDPRFTERAELFINTKEYANMYTELSDPIDQLERFESQLEE-KNKG-NDEASDIDYD 442
Query: 392 YLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRR 434
++ A EYGMPP GG G+G +RL+M + + +IR+V+LFP +R
Sbjct: 443 FVDALEYGMPPTGGCGIGIDRLVMLLTETDSIRDVLLFPTLKR 485
>sp|O84546|SYD_CHLTR ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|7437586|pir||G71500 aspartate--tRNA ligase (EC
6.1.1.12) - Chlamydia trachomatis (serotype D, strain
UW3/Cx) >gi|3328981|gb|AAC68144.1| (AE001325) Aspartyl
tRNA Synthetase [Chlamydia trachomatis]
Length = 582
Score = 125 bits (310), Expect = 1e-27
Identities = 92/296 (31%), Positives = 156/296 (52%), Gaps = 28/296 (9%)
Query: 3 RTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKL 62
RTH +E++ + G+ V+++GWV ++ GG+ FI +RD GI Q+ +++ P E+ +L
Sbjct: 4 RTHKCNELSLDHVGEHVRLSGWVHRYRNHGGVVFIDLRDCFGITQIVCRQEENP-ELHQL 62
Query: 63 IPKLNSEDVIVVEGIV------NFTPKAKLG-FEIIPEKLEVISKAKTPLPLDPTGK-VK 114
+ ++ SE V+ VEG+V P G E+ LEV+S+A+ LP + + +
Sbjct: 63 MDQVRSEWVLCVEGLVCARLEGMENPNLVTGSIEVEVSSLEVLSRAQN-LPFSISDEHIN 121
Query: 115 AELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTE 174
+ RL R++D+R ++ R V A R++ ++GF E+ TP + + EG +
Sbjct: 122 VNEELRLTYRYLDMRRGDILDRLMCRHKVMLACRQYLDEQGFTEVVTPILGKSTPEGARD 181
Query: 175 -LFPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDA 232
L P + + + + L QSPQL+KQ++M GLD+ F+I FR E+ R E ID
Sbjct: 182 YLVPSRIYPGNFYALPQSPQLFKQILMVGGLDRYFQIATCFRDEDLRADRQ-PEFTQIDM 240
Query: 233 EMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEA 288
EM+F E++ ++E L+ ++ + E K PF R+TY EA
Sbjct: 241 EMSF-GGPEDLFPVVEELV--------------ARLFAVKGIELKAPFLRMTYQEA 281
>pir||C81086 lysyl-tRNA synthetase, heat inducible NMB1425 [imported] -
Neisseria meningitidis (group B strain MD58)
>gi|7226664|gb|AAF41786.1| (AE002491) lysyl-tRNA
synthetase, heat inducible [Neisseria meningitidis MC58]
Length = 503
Score = 125 bits (310), Expect = 1e-27
Identities = 129/465 (27%), Positives = 209/465 (44%), Gaps = 45/465 (9%)
Query: 2 LRTHYSSEITEELN--GKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEI 59
L Y EEL+ G VKVAG + + +G F I+D G +Q+ K V QE+
Sbjct: 49 LHAQYGEIGKEELDPQGIPVKVAGRMMLKRQMGKASFATIQDVSGQIQLYLNNKGVSQEV 108
Query: 60 FKLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDT 119
+ D++ EG + T +L + + ++SK+ PLP G ++ +T
Sbjct: 109 LDDFNHWDLGDIVGAEGTLFKTNHGELTVRV--SGIRLLSKSLRPLPDKHKGL--SDQET 164
Query: 120 RLDNRFMDL-RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPL 178
+ R++DL N + F RS + ++ R F E ++E+ TP + GG P
Sbjct: 165 KYRQRYVDLIANEESRNTFIKRSQIIQSVRNFMVGEHYLEVETPMM--HPIPGGATAKPF 222
Query: 179 KYFEN----DAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEM 234
N +L +P+LY + ++ GL++VFEI FR E + RH E I+
Sbjct: 223 VTHHNALDIPLYLRIAPELYLKRLVVGGLERVFEINRSFR-NEGMSVRHNPEFTMIEFYE 281
Query: 235 AFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALE---- 290
AF + E +M + E +I V E +L + PF R+T EA++
Sbjct: 282 AFSDYER-MMQMAEDIIRNASRTVNGTANITYNGKEVDL---ESPFERLTILEAIKKYNP 337
Query: 291 -ILSDLGKEIPW-GEDIDTEGEKL-----LGKYML-------ENEGAELYFIYRYPSEAK 336
+ + W ++I GE L +G L E + FI YP E
Sbjct: 338 HYTDEQLNDAEWLKKEIVKHGESLPPSPGIGSLQLALFEGCAEGKLWNPTFIVDYPVEVS 397
Query: 337 PFYIMKYEDKPEVCKAFDLEYRGVEISSG----GQREHRHDILVEQIREKGL-NPESFEF 391
P + K + + F+L G E+++G E + + Q+ +K + E+ +
Sbjct: 398 PL-ARASDTKQGLTERFELFVVGRELANGYSELNDPEDQAERFKAQVVQKDAGDDEAMHY 456
Query: 392 ---YLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDR 433
Y+RA E+G+PP GG G+G +RL+M + D IR+VILFP+ R
Sbjct: 457 DADYIRAMEFGLPPTGGCGIGIDRLVMLLTDSQTIRDVILFPQMR 501
>sp|P21889|SYD_ECOLI ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|68534|pir||SYECD aspartate--tRNA ligase (EC
6.1.1.12) - Escherichia coli >gi|9256904|pdb|1EQR|A
Chain A, Crystal Structure Of Free Aspartyl-Trna
Synthetase From Escherichia Coli >gi|9256905|pdb|1EQR|B
Chain B, Crystal Structure Of Free Aspartyl-Trna
Synthetase From Escherichia Coli >gi|9256906|pdb|1EQR|C
Chain C, Crystal Structure Of Free Aspartyl-Trna
Synthetase From Escherichia Coli
>gi|41015|emb|CAA37856.1| (X53863) aspartate-tRNA ligase
[Escherichia coli] >gi|1736513|dbj|BAA15677.1| (D90829)
Aspartate--tRNA ligase (EC 6.1.1.12) [Escherichia coli]
>gi|1788173|gb|AAC74936.1| (AE000280) aspartate tRNA
synthetase [Escherichia coli K12]
Length = 590
Score = 122 bits (304), Expect = 6e-27
Identities = 85/258 (32%), Positives = 134/258 (50%), Gaps = 15/258 (5%)
Query: 2 LRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFK 61
+RT Y ++ G++V + GWV +DLG + FI +RDREGIVQV + + K
Sbjct: 1 MRTEYCGQLRLSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGIVQVFFDPDRA--DALK 58
Query: 62 LIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKT------PLPLDPTGKVKA 115
L +L +E I V G V + + ++ ++EV++ + T LPLD + V
Sbjct: 59 LASELRNEFCIQVTGTVRARDEKNINRDMATGEIEVLASSLTIINRADVLPLD-SNHVNT 117
Query: 116 ELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTE- 174
E + RL R++DLR P + K R+ + R F GF++I TP + EG +
Sbjct: 118 E-EARLKYRYLDLRRPEMAQRLKTRAKITSLVRRFMDDHGFLDIETPMLTKATPEGARDY 176
Query: 175 LFPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAE 233
L P + + + L QSPQL+KQ++M +G D+ ++I FR E+ R E ID E
Sbjct: 177 LVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQ-PEFTQIDVE 235
Query: 234 MAFIESEE--EVMDLLER 249
+F+ + + EVM+ L R
Sbjct: 236 TSFMTAPQVREVMEALVR 253
>sp|O83950|SYD_TREPA ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|7437587|pir||A71256 aspartate--tRNA ligase (EC
6.1.1.12) - syphilis spirochete
>gi|3323310|gb|AAC65942.1| (AE001266) aspartyl-tRNA
synthetase (aspS) [Treponema pallidum]
Length = 602
Score = 122 bits (304), Expect = 6e-27
Identities = 90/283 (31%), Positives = 141/283 (49%), Gaps = 24/283 (8%)
Query: 16 GKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVE 75
G V + GWV + G + F +RDR GIVQV +++ ++ + ++ E + VE
Sbjct: 32 GTVVVLNGWVHRKRSHGTVSFFNMRDRSGIVQVIVSQEE-NASLWSTVNRIRLECCLAVE 90
Query: 76 GIVNFTPKAKLGFEIIPEKLEVISKA------KTPLPLDPTGKVKAELDTRLDNRFMDLR 129
G+V P + + + ++EV ++ LP V A D RL R++DLR
Sbjct: 91 GVVRERPPSMINRALHTGEVEVHARTLYVLSENAVLPFRVDDVVHAHEDIRLKYRYLDLR 150
Query: 130 NPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTE-LFPLKYFENDAF-L 187
+ R+ +RS V A R+F +GFIEI TP I + EG + + P + + L
Sbjct: 151 SQRMQERIALRSRVALAIRQFLSMKGFIEIETPTFICSTPEGARDFVVPSRVCPGRFYAL 210
Query: 188 AQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLL 247
QSPQLYKQ++M G D+ F++ +R E+ R E ID EM+F+ S ++VM +
Sbjct: 211 PQSPQLYKQLLMVAGFDRYFQLARCYRDEDARGDRQ-PEFTQIDLEMSFV-SRDDVMRVN 268
Query: 248 ERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALE 290
E ++ YV R + EL FPR+TY +AL+
Sbjct: 269 EDMLRYVF---RTSIGVELPTF----------FPRLTYAQALD 298
>pdb|1C0A|A Chain A, Crystal Structure Of The E. Coli Aspartyl-Trna Synthetase
: Trnaasp : Aspartyl-Adenylate Complex
Length = 585
Score = 122 bits (304), Expect = 6e-27
Identities = 85/258 (32%), Positives = 134/258 (50%), Gaps = 15/258 (5%)
Query: 2 LRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFK 61
+RT Y ++ G++V + GWV +DLG + FI +RDREGIVQV + + K
Sbjct: 1 MRTEYCGQLRLSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGIVQVFFDPDRA--DALK 58
Query: 62 LIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKT------PLPLDPTGKVKA 115
L +L +E I V G V + + ++ ++EV++ + T LPLD + V
Sbjct: 59 LASELRNEFCIQVTGTVRARDEKNINRDMATGEIEVLASSLTIINRADVLPLD-SNHVNT 117
Query: 116 ELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTE- 174
E + RL R++DLR P + K R+ + R F GF++I TP + EG +
Sbjct: 118 E-EARLKYRYLDLRRPEMAQRLKTRAKITSLVRRFMDDHGFLDIETPMLTKATPEGARDY 176
Query: 175 LFPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAE 233
L P + + + L QSPQL+KQ++M +G D+ ++I FR E+ R E ID E
Sbjct: 177 LVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQ-PEFTQIDVE 235
Query: 234 MAFIESEE--EVMDLLER 249
+F+ + + EVM+ L R
Sbjct: 236 TSFMTAPQVREVMEALVR 253
>sp|P57401|SYD_BUCAI ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|10038990|dbj|BAB13024.1| (AP001119) aspartyl-tRNA
synthetase [Buchnera sp. APS]
Length = 586
Score = 122 bits (304), Expect = 6e-27
Identities = 97/298 (32%), Positives = 159/298 (52%), Gaps = 30/298 (10%)
Query: 2 LRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFK 61
+RT Y I KKVK+ GWV +V++LG F+ +RD G+VQV K +IFK
Sbjct: 1 MRTKYCGNIRISHVNKKVKLCGWVHKVRNLGQFIFVDMRDYTGLVQVIFELKN--YKIFK 58
Query: 62 LIPKLNSEDVIVVEGIV------NFTPKAKLG-FEIIPEKLEVISKAKTPLPLDPTGKVK 114
L +E I V G V N K + G EI+ L +++ +K+ LPL+ T +
Sbjct: 59 KALNLRNEFCIQVFGTVQKREKKNQNIKIRTGEIEILANVLNILNTSKS-LPLNFTQENN 117
Query: 115 AELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTE 174
D+RL R++DLR+ ++ KIR+ + R F K+ F++I TP + + EG +
Sbjct: 118 D--DSRLKYRYLDLRSFDILENLKIRNKITYLIRNFMTKKNFLDIETPILTKSTPEGARD 175
Query: 175 -LFPLK-YFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDA 232
L P + ++ L QSPQL+KQ++M +G+D+ ++I FR E+ + R E ID
Sbjct: 176 YLVPSRNHYGKFYALPQSPQLFKQILMISGIDRYYQIVKCFRDEDLRSDRQ-PEFTQIDI 234
Query: 233 EMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALE 290
E++F+ S +++ +L+E LI + +R N K+ FP+I++ EA++
Sbjct: 235 EVSFM-SAKKIRNLVENLIKKLWLEIRNINLKK--------------FPQISFHEAMK 277
>sp|Q50649|SYD_MYCTU ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|7437588|pir||C70724 aspartate--tRNA ligase (EC
6.1.1.12) - Mycobacterium tuberculosis (strain H37RV)
>gi|1478240|emb|CAB01271.1| (Z77724) aspS [Mycobacterium
tuberculosis]
Length = 596
Score = 121 bits (301), Expect = 1e-26
Identities = 94/306 (30%), Positives = 146/306 (46%), Gaps = 45/306 (14%)
Query: 1 MLRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF 60
+LR+H + + E G++V +AGWV +D GG+ FI +RD GI QV + E+
Sbjct: 3 VLRSHAAGLLREGDAGQQVTLAGWVARRRDHGGVIFIDLRDASGIAQVVF-RDPQDTEVL 61
Query: 61 KLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKT------PLPL---DPTG 111
+L +E + V G+V P+ EI ++EV + + T PLP +P G
Sbjct: 62 AQAHRLRAEFCVSVAGVVEIRPEGNANPEIATGEIEVNATSLTVLGECAPLPFQLDEPAG 121
Query: 112 KVKAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEG 171
+ + RL R++DLR + ++RS V A R + F+EI TP I + EG
Sbjct: 122 E-----ELRLKYRYLDLRRDDPAAAIRLRSRVNAAARAVLARHDFVEIETPTITRSTPEG 176
Query: 172 GTE-LFPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWS 229
+ L P + + L QSPQL+KQ++M G+++ ++I +R E+ R E
Sbjct: 177 ARDFLVPARLHPGSFYALPQSPQLFKQLLMVAGMERYYQIARCYRDEDFRADRQ-PEFTQ 235
Query: 230 IDAEMAFIESE------EEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRI 283
+D EM+F+++E EEV+ L LI Y I P PRI
Sbjct: 236 LDMEMSFVDAEDIIAISEEVLTELWALIGYRI---------------------PTPIPRI 274
Query: 284 TYDEAL 289
Y EA+
Sbjct: 275 GYAEAM 280
>sp|Q9Z7P2|SYD_CHLPN ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|7437604|pir||G72052 aspartate--tRNA ligase (EC
6.1.1.12) - Chlamydophila pneumoniae (strains CWL029 and
AR39) >gi|4376961|gb|AAD18801.1| (AE001648) Aspartyl
tRNA Synthetase [Chlamydophila pneumoniae CWL029]
>gi|7189021|gb|AAF37971.1| (AE002172) aspartyl-tRNA
synthetase [Chlamydophila pneumoniae AR39]
>gi|8979034|dbj|BAA98869.1| (AP002547) aspartyl tRNA
synthetase [Chlamydophila pneumoniae J138]
Length = 584
Score = 120 bits (298), Expect = 3e-26
Identities = 93/309 (30%), Positives = 155/309 (50%), Gaps = 20/309 (6%)
Query: 3 RTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKL 62
RTH +E+T G+ V++AGWV ++ GG+ FI +RDR GI Q+ + + P E+ +
Sbjct: 4 RTHRCNELTSNHIGENVQLAGWVHRYRNHGGVVFIDLRDRFGITQIVCREDEQP-ELHQR 62
Query: 63 IPKLNSEDVIVVEGIV------NFTPKAKLG-FEIIPEKLEVISKAKTPLPLD-PTGKVK 114
+ + SE V+ V G V P G E+ EV+SK++ LP +
Sbjct: 63 LDAVRSEWVLSVRGKVCPRLAGMENPNLATGHIEVEVASFEVLSKSQN-LPFSIADDHIN 121
Query: 115 AELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTE 174
+ RL+ R++D+R ++ R V A R F +GF EI TP + + EG +
Sbjct: 122 VNEELRLEYRYLDMRRGDIIEKLLCRHQVMLACRNFMDAQGFTEIVTPVLGKSTPEGARD 181
Query: 175 -LFPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDA 232
L P + + + L QSPQL+KQ++M GLD+ F+I FR E+ R E ID
Sbjct: 182 YLVPSRIYPGKFYALPQSPQLFKQLLMVGGLDRYFQIATCFRDEDLRADRQ-PEFAQIDI 240
Query: 233 EMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPF----PRITYDEA 288
EM+F ++ ++++ ++E+L+ + + + E L + + E K + P + +D
Sbjct: 241 EMSFGDT-QDLLPIIEQLVATL--FATQGIEIPLPLAKMTYQEAKDSYGTDKPDLRFDLK 297
Query: 289 LEILSDLGK 297
L+ D K
Sbjct: 298 LKDCRDYAK 306
>sp|O51402|SYD_BORBU ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
Length = 586
Score = 120 bits (297), Expect = 4e-26
Identities = 85/298 (28%), Positives = 144/298 (47%), Gaps = 29/298 (9%)
Query: 1 MLRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF 60
M + +E+ E+L KKV++ WV++++ G F+ IRDR QV ++K +
Sbjct: 1 MFKVIKCNELNEKLIDKKVEINAWVKKIRHHGKFIFLNIRDRYEKAQVLVNEEK----LL 56
Query: 61 KLIPKLNSEDVIVVEGIVNFTPKAKLG-------FEIIPEKLEVISKAKTPLPLDPTGKV 113
K+ K+ E I ++G++ P + FEI+ + +E+ISK LP
Sbjct: 57 KIAEKIKLEYCIKIQGLLIKRPPNMINANMKTGHFEILAKNIEIISKCNE-LPFMIEDDN 115
Query: 114 KAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGT 173
A +++L+ R++DLR + + +R R F K F+E+ TP + + EG
Sbjct: 116 NASENSKLEYRYLDLRRDSLKNKIILRCQATHLIRNFLIKRKFLELETPTFVKSTPEGAR 175
Query: 174 ELFPLKYFENDAFLA--QSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSID 231
+ +F A QSPQLYKQ++M G DK F+I +R E+ R E +D
Sbjct: 176 DFVIPSRIHKGSFYALPQSPQLYKQLIMIAGFDKYFQIARCYRDEDSRGDRQ-PEFTQLD 234
Query: 232 AEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEAL 289
EM+F++ +E + L+E ++ + +N PKK F +ITY +A+
Sbjct: 235 LEMSFVK-KENIFKLIENMLFLIFKNC------------ININLPKK-FKKITYKKAM 278
Score = 69.1 bits (166), Expect = 1e-10
Identities = 39/103 (37%), Positives = 56/103 (53%), Gaps = 6/103 (5%)
Query: 336 KPFYIMKYEDKPE--VCKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPES----F 389
K YI E P+ + + +DL GVE+ SG R H ++ + G E F
Sbjct: 453 KKQYIANLEKNPKKTIGEIYDLVLNGVELGSGSIRIHNKELQQRIFKIIGFQKEKSEDRF 512
Query: 390 EFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRD 432
F+L+A EYG P HGG +G +RLIM M +I++VILFP++
Sbjct: 513 GFFLKALEYGAPNHGGIAIGIDRLIMLMTKSTSIKDVILFPKN 555
>sp|Q9PEB6|SYK_XYLFA LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|11271299|pir||E82721 lysyl-tRNA synthetase XF1112
[imported] - Xylella fastidiosa (strain 9a5c)
>gi|9106069|gb|AAF83922.1|AE003947_2 (AE003947)
lysyl-tRNA synthetase [Xylella fastidiosa]
Length = 506
Score = 119 bits (295), Expect = 7e-26
Identities = 123/452 (27%), Positives = 203/452 (44%), Gaps = 49/452 (10%)
Query: 13 ELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVI 72
E +G +V++AG + + +G F I+D G +Q+ + ++ + L+ D+I
Sbjct: 64 EASGDRVRMAGRLMAKRLMGKASFAQIQDESGRIQLLIQSNVLGEDSYAAFKVLDVGDII 123
Query: 73 VVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDL-RNP 131
VEG + T +L ++ L +++KA PLP G +++ R R++DL P
Sbjct: 124 AVEGGLTRTRTGELSVKV--NVLRLLTKALRPLPDKWHG--LTDVEQRYRQRYVDLIVTP 179
Query: 132 RVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFEN----DAFL 187
IF RS + RA R + F+E+ TP + GG P + N + +L
Sbjct: 180 ESREIFIKRSKIIRALRTWLDARLFLEVETP--MMHYIPGGAAAKPFVTYHNALDLELYL 237
Query: 188 AQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLL 247
+P+LY + ++ GL++V+EI FR E +TRH E ++ A+ + EVMDL
Sbjct: 238 RVAPELYLKRLVVGGLERVYEINRNFR-NEGVSTRHNPEFTMLELYEAY-STYHEVMDLA 295
Query: 248 ERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIPWGEDIDT 307
E +I V + + +L F R DEA + EI E D
Sbjct: 296 ETMIRDTAQSVLGTTQVIWDGAQIDLG---PIFRRWRMDEA---VCHHNPEISVAECTDR 349
Query: 308 E-------------------GEKLLGKY--MLENEGAELYFIYRYPSEAKPFYIMKYEDK 346
+ G LL + +E+ + FI +P E P + + +
Sbjct: 350 DALLLHCERLKIKVKSSYGWGRLLLSIFEATVEHTLIQPTFITDHPVEISPL-ARESDIE 408
Query: 347 PEVCKAFDLEYRGVEISSG----GQREHRHDILVEQIREK-GLNPESFEF---YLRAFEY 398
P F+L G EI++G E + +Q+ K G + E+ + Y+RA EY
Sbjct: 409 PGYTDRFELFINGKEIANGFSELNDPEEQAMRFQKQVEAKEGGDDEAMYYDADYIRALEY 468
Query: 399 GMPPHGGFGLGAERLIMRMLDIGNIREVILFP 430
GM P GG G+G +RL+M + +IR+V+LFP
Sbjct: 469 GMAPTGGLGIGVDRLVMLLTGSTSIRDVLLFP 500
>gb|AAA24096.1| (M30630) lysyl-tRNA synthetase (lysU) (E.C. 6.1.1.6) [Escherichia
coli]
Length = 501
Score = 118 bits (293), Expect = 1e-25
Identities = 119/472 (25%), Positives = 197/472 (41%), Gaps = 56/472 (11%)
Query: 3 RTHYSSEITEELNGK----------KVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPK 52
R H S ++ EE + K +V VAG + + +G F+ ++D G +Q+ +
Sbjct: 42 RDHTSDQLHEEFDAKDNQELESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVAR 101
Query: 53 KKVPQEIFKLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGK 112
+P+ ++ K I+ G + T +L +L +++KA PLP G
Sbjct: 102 DSLPEGVYNDQFKKWDLGDIIGAGTLFKTQTGELSIHCT--ELRLLTKALRPLPDKFHGL 159
Query: 113 VKAELDTRLDNRFMDL-RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEG 171
E+ R R++DL N + F +RS + A R+F GF+E+ TP + G
Sbjct: 160 QDQEV--RYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMM--QVIPG 215
Query: 172 GTELFPLKYFEN----DAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEA 227
G P N D + +P+LY + ++ G ++VFE RH E
Sbjct: 216 GASARPFITHHNALDLDMYARIAPELYLKRLVVGGFERVFE----HVTRNEGIRRHNPEF 271
Query: 228 WSIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDE 287
++ MA+ + + +++L E L + V + F+ KPF ++T E
Sbjct: 272 TMMELYMAYADYHD-LIELTESLFRTLAQEVLGTTKVTYGEHVFDFG---KPFEKLTMRE 327
Query: 288 ALEI---------LSDLGKEIPWGEDIDTEGEKLLG---------KYMLENEGAELYFIY 329
A++ L + E I EK G ++E + FI
Sbjct: 328 AIKKYRPETDMADLDNFDARKALAESIGITVEKSWGLGRSVTEIFDEVVEGHVIQPSFIT 387
Query: 330 RYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSG----GQREHRHDILVEQIREKGLN 385
YP+E P + + PE+ F+ G EI +G E + + EQ+ K
Sbjct: 388 EYPAEVSPL-ARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAG 446
Query: 386 PESFEFY----LRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDR 433
+ FY + A EYG+PP G G+G +R+IM + IR+VILFP R
Sbjct: 447 DDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMIMLFTNSHTIRDVILFPAMR 498
>sp|P36429|SYD_MYCLE ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS) (ANTIGEN
T5) >gi|541455|pir||S42047 aspartate--tRNA ligase (EC
6.1.1.12) - Mycobacterium leprae
>gi|581332|emb|CAA54735.1| (X77655) aspartyl-tRNA
synthetase [Mycobacterium leprae]
>gi|3136016|emb|CAA19094.1| (AL023591) aspartyl-tRNA
synthetase [Mycobacterium leprae]
>gi|3335328|gb|AAC27132.1|S82268_1 (S82268)
aspartyl-tRNA synthetase [Mycobacterium leprae]
Length = 589
Score = 118 bits (292), Expect = 2e-25
Identities = 90/306 (29%), Positives = 141/306 (45%), Gaps = 48/306 (15%)
Query: 1 MLRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIF 60
MLR+H + + + G++V +AGWV +D GG+ FI +RD GI Q + ++
Sbjct: 1 MLRSHGAGVLRKSDAGQQVTLAGWVSRRRDHGGVIFIDLRDSSGITQAVFRE----PDVL 56
Query: 61 KLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKT------PLPL---DPTG 111
+L +E I V G+V P+ EI +EV + + T PLP +P G
Sbjct: 57 AQAHRLRAEFCIAVSGVVEIRPEGNANAEIPTGDIEVNATSLTVLGESAPLPFQLDEPAG 116
Query: 112 KVKAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEG 171
+ + RL R++DLR S ++RS V R + F+EI TP I + EG
Sbjct: 117 E-----ELRLKYRYLDLRRDGPGSAIRLRSKVNATARAVLARHDFVEIETPTITRSTPEG 171
Query: 172 GTELFPLKYFENDAF--LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWS 229
+ F L QSPQL+KQ++M G+++ ++I +R E+ R E
Sbjct: 172 ARDFLVPARLRPGTFYALPQSPQLFKQLLMVAGMERYYQIAHCYRDEDFRADRQ-PEFTQ 230
Query: 230 IDAEMAFIESE------EEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRI 283
+D EM+F+++E EE++ L LI Y I P PRI
Sbjct: 231 LDMEMSFVDAEDVIAISEEILTELWMLIGYHI---------------------PAPIPRI 269
Query: 284 TYDEAL 289
+Y +A+
Sbjct: 270 SYADAM 275
>pir||S69892 lysine--tRNA ligase (EC 6.1.1.6) - Mycoplasma hominis
Length = 488
Score = 116 bits (289), Expect = 4e-25
Identities = 115/429 (26%), Positives = 200/429 (45%), Gaps = 50/429 (11%)
Query: 36 FIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKL 95
FI ++D G +Q+ A KK + + K ++ D++ V G ++ T L I + +
Sbjct: 72 FIVLQDNCGQMQIYANKKTLNESSAKTFSLMDFGDILSVRGTLSKTNTDAL--VIKAQDI 129
Query: 96 EVISKAKTPLPLDPTGKVKAELDTRLDNRFMDL-RNPRVMSIFKIRSSVFRATREFFYKE 154
+++K+ PLP G V E R R++DL N + + F +R+ + + RE+F
Sbjct: 130 VLLTKSLKPLPDKFHGLVDPE--ERRRQRYVDLIMNEKTRNTFVMRTQIIKGIREYFDSL 187
Query: 155 GFIEIHTPKIIATATEGGTELFPLKYFEN----DAFLAQSPQLYKQMMMSTGLDKVFEIG 210
+IE+ TP I GG P F N + +L + +L + ++ GLD+V+EIG
Sbjct: 188 NYIEVDTP--ILNPILGGAAAKPFITFYNALNRNFYLRIATELPLKKLIVGGLDRVYEIG 245
Query: 211 PIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILE 270
IFR E +TT H E SI+ F E+ ++ ++ER + + + N KE+K
Sbjct: 246 RIFRNEGVDTT-HNPEFTSIE----FYEAYSDLWGMMERTEGVFKHLINKFNIKEVKFNG 300
Query: 271 FELNEPKKPFPRITYDEAL-------------EILSDLGKE--------IPWGEDIDTEG 309
F++ PF R+ +A+ E + +L K+ +G I+
Sbjct: 301 FDITF-NFPFKRVNMIDAISEKINVDIRKLNEEQMFELAKKHGIKIEKFFRYGHIINELF 359
Query: 310 EKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAF----DLEYRGVEISSG 365
EK + + ++E F+Y +P E P + +DK +A E+ +
Sbjct: 360 EKYVEETLIEPT-----FVYGHPIEISPLAAIDPDDKRFTLRAELFIGTKEFANMFTELN 414
Query: 366 GQREHRHDILVEQIREKGLNPESFEF---YLRAFEYGMPPHGGFGLGAERLIMRMLDIGN 422
+ + + ++ N E+ E ++ A EYGMPP GG G+G +RLIM + +
Sbjct: 415 DPIDQLQRFENQLLEKENGNEEANEIDWDFVNALEYGMPPTGGSGIGIDRLIMLLTQNDS 474
Query: 423 IREVILFPR 431
IR+V+LFP+
Sbjct: 475 IRDVVLFPQ 483
>sp|P37879|SYK_CRILO LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|543180|pir||S43187 lysine--tRNA ligase (EC 6.1.1.6)
- long-tailed hamster >gi|469122|emb|CAA83505.1|
(Z31711) Lysyl tRNA Synthetase [Cricetulus
longicaudatus]
Length = 597
Score = 116 bits (289), Expect = 4e-25
Identities = 127/470 (27%), Positives = 207/470 (44%), Gaps = 68/470 (14%)
Query: 12 EELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGI-VQVTAPKK--KVPQEIFKLIPKLNS 68
+ L +KVAG + + GG + EG+ +QV A + K +E ++ KL
Sbjct: 119 DHLTDITLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFVRINNKLRR 178
Query: 69 EDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDL 128
D+I V+G T K +L IIP ++ ++S LP G E TR R++DL
Sbjct: 179 GDIIGVQGNPGKTKKGELS--IIPYEITLLSPCLHMLPHLHFGLKDKE--TRYRQRYLDL 234
Query: 129 -RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDA-- 185
N V F +R+ + R F + GF+EI TP + GG P + N+
Sbjct: 235 ILNDFVRQKFIVRAKIITYIRSFLDELGFLEIETPMM--NIIPGGAVAKPFITYHNELDM 292
Query: 186 --FLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEV 243
++ +P+LY +M++ G+D+V+EIG FR E + T H E + + MA+ + + +
Sbjct: 293 NLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLT-HNPEFTTCEFYMAYADYHD-L 350
Query: 244 MDLLERLIL---------YVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSD 294
M++ E+++ Y I Y + E E ++F PF RI+ E LE
Sbjct: 351 MEITEKMLSGMVKSITGSYKITYHPDGPEGEAYEIDFT-----PPFRRISMVEELE--KA 403
Query: 295 LGKEIPWGEDIDTEG--------------------------EKLLGKYMLENEGAELYFI 328
LG ++P +TE +KL+G++ LE FI
Sbjct: 404 LGVKLPETSLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEF-LEVTCINPTFI 462
Query: 329 YRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSG----GQREHRHDILVEQIREKGL 384
+P P + K + + F+L EI + + + EQ + K
Sbjct: 463 CDHPQIMSPL-AKWHRSKEGLTERFELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAA 521
Query: 385 NPESFEF----YLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFP 430
+ F + A EYG+PP G+G+G +R+ M + D NI+EV+LFP
Sbjct: 522 GDDEAMFIDENFCTALEYGLPPTAGWGMGIDRVTMFLTDSNNIKEVLLFP 571
>dbj|BAA06688.1| (D31890) similar to lysyl tRNA synthetase. [Homo sapiens]
Length = 601
Score = 116 bits (287), Expect = 6e-25
Identities = 127/470 (27%), Positives = 205/470 (43%), Gaps = 68/470 (14%)
Query: 12 EELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGI-VQVTAPKK--KVPQEIFKLIPKLNS 68
+ L +KVAG + + GG + EG+ +QV A + K +E + KL
Sbjct: 123 DHLTDITLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFIHINNKLRR 182
Query: 69 EDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDL 128
D+I V+G T K +L IIP ++ ++S LP G E TR R++DL
Sbjct: 183 GDIIGVQGNPGKTKKGELS--IIPYEITLLSPCLHMLPHLHFGLKDKE--TRYRQRYLDL 238
Query: 129 -RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDA-- 185
N V F IRS + R F + GF+EI TP + GG P + N+
Sbjct: 239 ILNDFVRQKFIIRSKIITYIRSFLDELGFLEIETPMM--NIIPGGAVAKPFITYHNELDM 296
Query: 186 --FLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEV 243
++ +P+LY +M++ G+D+V+EIG FR E + T H E + + MA+ + + +
Sbjct: 297 NLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLT-HNPEFTTCEFYMAYADYHD-L 354
Query: 244 MDLLERLIL---------YVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSD 294
M++ E+++ Y + Y + E + ++F PF RI E LE
Sbjct: 355 MEITEKMVSGMVKHITGSYKVTYHPDGPEGQAYDVDFT-----PPFRRINMVEELE--KA 407
Query: 295 LGKEIPWGEDIDTEG--------------------------EKLLGKYMLENEGAELYFI 328
LG ++P +TE +KL+G++ LE FI
Sbjct: 408 LGMKLPETNLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEF-LEVTCINPTFI 466
Query: 329 YRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSG----GQREHRHDILVEQIREKGL 384
+P P + K + + F+L EI + + + EQ + K
Sbjct: 467 CDHPQIMSPL-AKWHRSKEGLTERFELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAA 525
Query: 385 NPESFEF----YLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFP 430
+ F + A EYG+PP G+G+G +R+ M + D NI+EV+LFP
Sbjct: 526 GDDEAMFIDENFCTALEYGLPPTAGWGMGIDRVAMFLTDSNNIKEVLLFP 575
>gi|5031815 lysyl-tRNA synthetase; lysine tRNA ligase [Homo sapiens]
>gi|11525803|ref|XP_007820.1| lysyl-tRNA synthetase
[Homo sapiens] >gi|2366752|dbj|BAA22084.1| (D32053)
Lysyl tRNA Synthetase [Homo sapiens]
Length = 597
Score = 116 bits (287), Expect = 6e-25
Identities = 127/470 (27%), Positives = 205/470 (43%), Gaps = 68/470 (14%)
Query: 12 EELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGI-VQVTAPKK--KVPQEIFKLIPKLNS 68
+ L +KVAG + + GG + EG+ +QV A + K +E + KL
Sbjct: 119 DHLTDITLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFIHINNKLRR 178
Query: 69 EDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDL 128
D+I V+G T K +L IIP ++ ++S LP G E TR R++DL
Sbjct: 179 GDIIGVQGNPGKTKKGELS--IIPYEITLLSPCLHMLPHLHFGLKDKE--TRYRQRYLDL 234
Query: 129 -RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDA-- 185
N V F IRS + R F + GF+EI TP + GG P + N+
Sbjct: 235 ILNDFVRQKFIIRSKIITYIRSFLDELGFLEIETPMM--NIIPGGAVAKPFITYHNELDM 292
Query: 186 --FLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEV 243
++ +P+LY +M++ G+D+V+EIG FR E + T H E + + MA+ + + +
Sbjct: 293 NLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLT-HNPEFTTCEFYMAYADYHD-L 350
Query: 244 MDLLERLIL---------YVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSD 294
M++ E+++ Y + Y + E + ++F PF RI E LE
Sbjct: 351 MEITEKMVSGMVKHITGSYKVTYHPDGPEGQAYDVDFT-----PPFRRINMVEELE--KA 403
Query: 295 LGKEIPWGEDIDTEG--------------------------EKLLGKYMLENEGAELYFI 328
LG ++P +TE +KL+G++ LE FI
Sbjct: 404 LGMKLPETNLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEF-LEVTCINPTFI 462
Query: 329 YRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSG----GQREHRHDILVEQIREKGL 384
+P P + K + + F+L EI + + + EQ + K
Sbjct: 463 CDHPQIMSPL-AKWHRSKEGLTERFELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAA 521
Query: 385 NPESFEF----YLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFP 430
+ F + A EYG+PP G+G+G +R+ M + D NI+EV+LFP
Sbjct: 522 GDDEAMFIDENFCTALEYGLPPTAGWGMGIDRVAMFLTDSNNIKEVLLFP 571
>sp|Q15046|SYK_HUMAN LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS) (KIAA0070)
Length = 597
Score = 116 bits (287), Expect = 6e-25
Identities = 127/470 (27%), Positives = 205/470 (43%), Gaps = 68/470 (14%)
Query: 12 EELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGI-VQVTAPKK--KVPQEIFKLIPKLNS 68
+ L +KVAG + + GG + EG+ +QV A + K +E + KL
Sbjct: 119 DHLTDITLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFIHINNKLRR 178
Query: 69 EDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDL 128
D+I V+G T K +L IIP ++ ++S LP G E TR R++DL
Sbjct: 179 GDIIGVQGNPGKTKKGELS--IIPYEITLLSPCLHMLPHLHFGLKDKE--TRYRQRYLDL 234
Query: 129 -RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDA-- 185
N V F IRS + R F + GF+EI TP + GG P + N+
Sbjct: 235 ILNDFVRQKFIIRSKIITYIRSFLDELGFLEIETPMM--NIIPGGAVAKPFITYHNELDM 292
Query: 186 --FLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEV 243
++ +P+LY +M++ G+D+V+EIG FR E + T H E + + MA+ + + +
Sbjct: 293 NLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLT-HNPEFTTCEFYMAYADYHD-L 350
Query: 244 MDLLERLIL---------YVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSD 294
M++ E+++ Y + Y + E + ++F PF RI E LE
Sbjct: 351 MEITEKMVSGMVKHITGSYKVTYHPDGPEGQAYDVDFT-----PPFRRINMVEELE--KA 403
Query: 295 LGKEIPWGEDIDTEG--------------------------EKLLGKYMLENEGAELYFI 328
LG ++P +TE +KL+G++ LE FI
Sbjct: 404 LGMKLPETNLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEF-LEVTCINPTFI 462
Query: 329 YRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSG----GQREHRHDILVEQIREKGL 384
+P P + K + + F+L EI + + + EQ + K
Sbjct: 463 CDHPQIMSPL-AKWHRSKEGLTERFELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAA 521
Query: 385 NPESFEF----YLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFP 430
+ F + A EYG+PP G+G+G +R+ M + D NI+EV+LFP
Sbjct: 522 GDDEAMFIDENFCTALEYGLPPTAGWGMGIDRVAMFLTDSNNIKEVLLFP 571
>gb|AAG30114.1|AF285758_1 (AF285758) lysyl-tRNA synthetase [Homo sapiens]
Length = 625
Score = 116 bits (287), Expect = 6e-25
Identities = 127/470 (27%), Positives = 205/470 (43%), Gaps = 68/470 (14%)
Query: 12 EELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGI-VQVTAPKK--KVPQEIFKLIPKLNS 68
+ L +KVAG + + GG + EG+ +QV A + K +E + KL
Sbjct: 147 DHLTDITLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFIHINNKLRR 206
Query: 69 EDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDL 128
D+I V+G T K +L IIP ++ ++S LP G E TR R++DL
Sbjct: 207 GDIIGVQGNPGKTKKGELS--IIPYEITLLSPCLHMLPHLHFGLKDKE--TRYRQRYLDL 262
Query: 129 -RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDA-- 185
N V F IRS + R F + GF+EI TP + GG P + N+
Sbjct: 263 ILNDFVRQKFIIRSKIITYIRSFLDELGFLEIETPMM--NIIPGGAVAKPFITYHNELDM 320
Query: 186 --FLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEV 243
++ +P+LY +M++ G+D+V+EIG FR E + T H E + + MA+ + + +
Sbjct: 321 NLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLT-HNPEFTTCEFYMAYADYHD-L 378
Query: 244 MDLLERLIL---------YVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSD 294
M++ E+++ Y + Y + E + ++F PF RI E LE
Sbjct: 379 MEITEKMVSGMVKHITGSYKVTYHPDGPEGQAYDVDFT-----PPFRRINMVEELE--KA 431
Query: 295 LGKEIPWGEDIDTEG--------------------------EKLLGKYMLENEGAELYFI 328
LG ++P +TE +KL+G++ LE FI
Sbjct: 432 LGMKLPETNLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEF-LEVTCINPTFI 490
Query: 329 YRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSG----GQREHRHDILVEQIREKGL 384
+P P + K + + F+L EI + + + EQ + K
Sbjct: 491 CDHPQIMSPL-AKWHRSKEGLTERFELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAA 549
Query: 385 NPESFEF----YLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFP 430
+ F + A EYG+PP G+G+G +R+ M + D NI+EV+LFP
Sbjct: 550 GDDEAMFIDENFCTALEYGLPPTAGWGMGIDRVAMFLTDSNNIKEVLLFP 599
>sp|P81432|SYD_BUCAP ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|2947034|gb|AAC05432.1| (L43549) aspartyl-tRNA
synthetase [Buchnera aphidicola]
Length = 584
Score = 115 bits (286), Expect = 8e-25
Identities = 91/296 (30%), Positives = 152/296 (50%), Gaps = 28/296 (9%)
Query: 2 LRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFK 61
+RT Y I K V + GWV ++++ FI +RD GIVQ+ KK ++F
Sbjct: 1 MRTKYCGNIRIIDLHKSVILCGWVHKIRNFSQFIFIDMRDWTGIVQLVFEKKN--NKVFT 58
Query: 62 LIPKLNSEDVIVVEGIV-----NFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAE 116
L +E I V GIV N EI+ K++V + +K LPLD + +
Sbjct: 59 KAVNLKNESCIQVIGIVKKRNANNNNLDTGEIEILVNKIKVFNISKN-LPLDYSNN--SN 115
Query: 117 LDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTE-L 175
D RL R++DLR ++ KIR+ + R F + F++I TP + + EG + L
Sbjct: 116 DDIRLKYRYLDLRRSELLENLKIRNKITHLIRIFMENKNFLDIETPFLTKSTPEGARDYL 175
Query: 176 FPLKYFENDAF-LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEM 234
P + + + + L QSPQL+KQ++M +G+DK ++I FR E+ + R E ID E
Sbjct: 176 VPSRNYPGNFYALPQSPQLFKQILMISGIDKYYQIVKCFRDEDLRSDRQ-PEFTQIDIEA 234
Query: 235 AFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALE 290
+F+ S ++ +L+E LI + LK++ + LN+ FP+I++ ++++
Sbjct: 235 SFV-SSTKIRNLVETLIKKI----------WLKVINYNLNK----FPKISFYDSMK 275
>sp|Q22099|SYK_CAEEL PROBABLE LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|7437595|pir||T16780 hypothetical protein T02G5.9 -
Caenorhabditis elegans >gi|1086773|gb|AAA82396.1|
(U41105) coded for by C. elegans cDNA yk124d11.3; coded
for by C. elegans cDNA yk48a4.3; coded for by C. elegans
cDNA yk124d11.5; coded for by C. elegans cDNA cm7h5;
coded for by C. elegans cDNA cm7a10; similar to class
II aminoacyl-tRNA synthetases [>
Length = 572
Score = 114 bits (282), Expect = 2e-24
Identities = 125/479 (26%), Positives = 208/479 (43%), Gaps = 63/479 (13%)
Query: 4 THYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGI-VQVTAPKKKVPQEI--F 60
T Y+ E++ + V VAG + ++ G + EG +Q+ A K ++
Sbjct: 90 TKYTPLEKEQVVEEIVSVAGRIHSKRESGSKLVFYDIHGEGTHIQIMANAKFHTGDVDFV 149
Query: 61 KLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTR 120
L ++ D++ G T +L +IP ++ ++ LP G EL R
Sbjct: 150 TLHDRIKRGDIVGFTGRATRTKAGELS--LIPNEILQLTPCLHMLPHSHFGLKDKEL--R 205
Query: 121 LDNRFMDL-RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLK 179
R++DL NPRV F IRS + R + GF+E+ TP I GG P
Sbjct: 206 FRKRYLDLILNPRVKDNFVIRSKIITFLRRYLDNLGFLEVETP--IMNQIAGGATAKPFI 263
Query: 180 YFENDA----FLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMA 235
ND FL +P+LY +M++ G+D+V+E+G +FR E + T H E + + MA
Sbjct: 264 THHNDLDMNLFLRVAPELYHKMLVVGGIDRVYEVGRLFRNEGIDLT-HNPEFTTCEFYMA 322
Query: 236 FIESEEEVM---DLLERLIL-----YVINYVRENNEKELKILEFELNEPKK--------- 278
+ + E+ + DLL +++ Y I Y N + E + P K
Sbjct: 323 YADYEDVIQLTEDLLSSMVMSIKGTYKIEY-HPNGPNTEPVYEVDFTPPFKRVHMYDGLA 381
Query: 279 -------PFPRITY-DEALEILSDLGKEIPWGEDIDTEG--------EKLLGKYMLENEG 322
P P + +EA E+ L ++ ++D +KL+G+Y LE+
Sbjct: 382 EKLGATLPDPSTLHTEEAREVFDKLCRD----NNVDCSAPRTTARLLDKLVGEY-LESTF 436
Query: 323 AELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSGGQREH----RHDILVEQ 378
F+ +P P + P + + F+L EI++ + + +Q
Sbjct: 437 ISPTFLIGHPQIMSPL-AKWHRSIPGLTERFELFAVTREIANAYTELNDPITQRQRFEQQ 495
Query: 379 IREKGLNPESF----EFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDR 433
++K + E + A EYG+PP GG+G+G +RL M + D NI+EV+LFP R
Sbjct: 496 AKDKDAGDDEAQMIDETFCNALEYGLPPTGGWGMGIDRLSMILTDNNNIKEVLLFPAMR 554
>emb|CAA39699.1| (X56259) lysine--tRNA ligase [Saccharomyces cerevisiae]
Length = 591
Score = 114 bits (282), Expect = 2e-24
Identities = 127/474 (26%), Positives = 208/474 (43%), Gaps = 71/474 (14%)
Query: 12 EELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGI-VQVTAPKKKV--PQEIFKLIPKLNS 68
E L +KV +AG + ++ G ++ +G+ VQ+ + + P+ K L
Sbjct: 117 ETLPEEKVSIAGRIHAKRESGSKLKFYVLHGDGVEVQLMSQLQDYHDPESYEKDHDLLKR 176
Query: 69 EDVIVVEGIVNFTPKAKLG---FEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRF 125
D++ VEG V T K G + ++++++ LP D G E TR R+
Sbjct: 177 GDIVGVEGYVGRTQPKKGGEGEVSVFVSRVQLLTPCLHMLPADHFGFKDQE--TRYRKRY 234
Query: 126 MDL-RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFEND 184
+DL N + F RS + R R+F + FIE+ TP + A GG P ND
Sbjct: 235 LDLIMNKDARNRFITRSEIIRYIRKFLDQRKFIEVETPMMNVIA--GGATAKPFITHHND 292
Query: 185 A----FLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESE 240
++ +P+L+ + ++ GLD+V+EIG FR E + T H E + + F ++
Sbjct: 293 LDMDMYMRIAPELFLKQLVVGGLDRVYEIGRQFRNEGIDMT-HNPEFTTCE----FYQAY 347
Query: 241 EEVMDLLERLILYVINYVRENNEKEL---------KILEFELNEPKKPFPRITYDEALEI 291
+V DL++ L V+E + E ELN +P+ RI E LE
Sbjct: 348 ADVYDLMDMTELMFSEMVKEITGSYIIKYHPDPADPAKELELNF-SRPWKRINMIEELEK 406
Query: 292 LSDLGKEIPWGEDIDTEG--------------------------EKLLGKYMLENEGAEL 325
+ ++ + P G+ + T +KL+G+ LE+
Sbjct: 407 VFNV--KFPSGDQLHTAETGEFLKKVLADNKLECPPPLTNARMLDKLVGE--LEDTCINP 462
Query: 326 YFIYRYPSEAKPFYIMKYE-DKPEVCKAFDLEYRGVEISSGGQREH----RHDILVEQIR 380
FI+ +P P + KY D+P +C+ F++ EI + + + EQ R
Sbjct: 463 TFIFGHPQMMSP--LAKYSRDQPGLCERFEVFVATKEICNAYTELNDPFDQRARFEEQAR 520
Query: 381 EKGLNPESF----EFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFP 430
+K + E + A EYG+PP GG+G G +RL M + D IREV+LFP
Sbjct: 521 QKDQGDDEAQLVDETFCNALEYGLPPTGGWGCGIDRLAMFLTDSNTIREVLLFP 574
>gi|6320242 lysyl-tRNA synthetase; Krs1p [Saccharomyces cerevisiae]
>gi|135139|sp|P15180|SYKC_YEAST LYSYL-TRNA SYNTHETASE,
CYTOPLASMIC (LYSINE--TRNA LIGASE) (LYSRS)
>gi|68528|pir||SYBYKT lysine--tRNA ligase (EC 6.1.1.6) -
yeast (Saccharomyces cerevisiae)
>gi|171799|gb|AAA66916.1| (J04186) lysyl-tRNA synthetase
[Saccharomyces cerevisiae] >gi|1122359|emb|CAA92376.1|
(Z68196) Krs1p [Saccharomyces cerevisiae]
>gi|1431484|emb|CAA98863.1| (Z74333) ORF YDR037w
[Saccharomyces cerevisiae]
Length = 591
Score = 113 bits (281), Expect = 3e-24
Identities = 127/472 (26%), Positives = 208/472 (43%), Gaps = 67/472 (14%)
Query: 12 EELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGI-VQVTAPKKKV--PQEIFKLIPKLNS 68
E L +KV +AG + ++ G ++ +G+ VQ+ + + P K L
Sbjct: 117 ETLPEEKVSIAGRIHAKRESGSKLKFYVLHGDGVEVQLMSQLQDYCDPDSYEKDHDLLKR 176
Query: 69 EDVIVVEGIVNFTPKAKLG---FEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRF 125
D++ VEG V T K G + ++++++ LP D G E TR R+
Sbjct: 177 GDIVGVEGYVGRTQPKKGGEGEVSVFVSRVQLLTPCLHMLPADHFGFKDQE--TRYRKRY 234
Query: 126 MDL-RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFEND 184
+DL N + F RS + R R F + FIE+ TP + A GG P ND
Sbjct: 235 LDLIMNKDARNRFITRSEIIRYIRRFLDQRKFIEVETPMMNVIA--GGATAKPFITHHND 292
Query: 185 A----FLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESE 240
++ +P+L+ + ++ GLD+V+EIG FR E + T H E + + F ++
Sbjct: 293 LDMDMYMRIAPELFLKQLVVGGLDRVYEIGRQFRNEGIDMT-HNPEFTTCE----FYQAY 347
Query: 241 EEVMDLLERLILYVINYVRE---------NNEKELKILEFELNEPKKPFPRITYDEALEI 291
+V DL++ L V+E + + E ELN +P+ RI E LE
Sbjct: 348 ADVYDLMDMTELMFSEMVKEITGSYIIKYHPDPADPAKELELNF-SRPWKRINMIEELEK 406
Query: 292 LSDLGKEIPWGEDIDT-EGEKLLGKYMLENE--------GAELY---------------F 327
+ ++ + P G+ + T E + L K +++N+ A + F
Sbjct: 407 VFNV--KFPSGDQLHTAETGEFLKKILVDNKLECPPPLTNARMLDKLVGELEDTCINPTF 464
Query: 328 IYRYPSEAKPFYIMKY-EDKPEVCKAFDLEYRGVEISSG----GQREHRHDILVEQIREK 382
I+ +P P + KY D+P +C+ F++ EI + + EQ R+K
Sbjct: 465 IFGHPQMMSP--LAKYSRDQPGLCERFEVFVATKEICNAYTELNDPFDQRARFEEQARQK 522
Query: 383 GLNPESF----EFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFP 430
+ E + A EYG+PP GG+G G +RL M + D IREV+LFP
Sbjct: 523 DQGDDEAQLVDETFCNALEYGLPPTGGWGCGIDRLAMFLTDSNTIREVLLFP 574
>sp|Q9PR83|SYK_UREPA LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|11271293|pir||G82937 lysyl-tRNA synthetase UU062
[imported] - Ureaplasma urealyticum
>gi|6899012|gb|AAF30467.1|AE002106_1 (AE002106)
lysyl-tRNA synthetase [Ureaplasma urealyticum]
Length = 493
Score = 113 bits (280), Expect = 4e-24
Identities = 114/457 (24%), Positives = 206/457 (44%), Gaps = 48/457 (10%)
Query: 5 HYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIP 64
++S E ++ +K+ +AG + ++ GI I+D +Q+ KK V E+F
Sbjct: 47 NFSKEELHNMDLEKLTLAGRLIGIRQTFGI----IQDFSAKLQIYINKKNVAPEVFSTFK 102
Query: 65 KLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNR 124
L+ D+I +EG+ T ++ + + +++K+ LP G V E+ R R
Sbjct: 103 SLDIGDIIELEGVAMKTNSDEITLNV--TNIRLVAKSLKVLPEKYHGLVDEEIKAR--QR 158
Query: 125 FMDL-RNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKY--F 181
++DL N + F RS + R R + +GF E+ TP + + F +
Sbjct: 159 YLDLIVNDETKNTFIKRSLIIREMRNWLDNKGFFEVETPVLQDILSGAAARPFITHHNTL 218
Query: 182 ENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEE 241
+ +L + ++ + + G +KV+EIG IFR E ++T H E S++ +A+++
Sbjct: 219 NKEYYLRIATEIALKKCIIGGFEKVYEIGRIFRNEGMDST-HNPEFTSVELYIAYVDL-W 276
Query: 242 EVMDLLERLILYVINYVRENNEKELKILEFELNEPKKP--------------FPRITYDE 287
+M L E LI ++ + N + +LN+P K F + DE
Sbjct: 277 YIMQLTEDLIRHIATKLNLLN-PTFRGFSIDLNKPFKKAHMVDLINEYVGVNFFEVKSDE 335
Query: 288 -ALEILSD-----LGKEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIM 341
A+E+ L + +G ++ E +E + E F+Y +P + P
Sbjct: 336 QAIELAKKHHVKLLDHQKNFGHIVNAFFET-----FVEEKLVEPTFVYGHPLQVSPL-TK 389
Query: 342 KYEDKPEVCKAFDLEYRGVEISSGGQREH----RHDILVEQIREKGL-NPESFEF---YL 393
K + P F+L E ++ + +++ + Q+ E L N E+ E ++
Sbjct: 390 KNQSDPRFVDRFELFICQKEFANAYSEINDPIDQYERFIAQLEEAKLGNDEASELDMEFI 449
Query: 394 RAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFP 430
A EYGMPP GG G+G +RL+M + +IR V+LFP
Sbjct: 450 EALEYGMPPTGGLGIGVDRLVMLLTSNDSIRNVLLFP 486
>sp|P46191|SYK_MYCHO LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|581319|emb|CAA52877.1| (X74912) putative lysyl-tRNA
synthetase [Mycoplasma hominis]
Length = 488
Score = 112 bits (278), Expect = 7e-24
Identities = 112/429 (26%), Positives = 198/429 (46%), Gaps = 50/429 (11%)
Query: 36 FIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKL 95
FI ++D G +Q+ A KK + + K ++ D++ V G ++ T L + + +
Sbjct: 72 FIVLQDNCGQMQIYANKKTLNESSAKTFSLMDFGDILSVRGTLSKTNTDALVMKA--QDM 129
Query: 96 EVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLR-NPRVMSIFKIRSSVFRATREFFYKE 154
++K+ PLP G V E R R++DL N + + F +R+ + + RE+F
Sbjct: 130 VTLTKSLKPLPDKFHGLVDPE--ERRRQRYVDLMMNEKTRNTFVMRTQIIKGIREYFDSL 187
Query: 155 GFIEIHTPKIIATATEGGTELFPLKYFEN----DAFLAQSPQLYKQMMMSTGLDKVFEIG 210
+IE+ TP I GG P F N + +L + +L + ++ GLD+V+EIG
Sbjct: 188 NYIEVDTP--ILNPMLGGAAAKPFITFYNATNRNFYLRIATELPLKKLIVGGLDRVYEIG 245
Query: 211 PIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILE 270
+FR E +TT H E SI+ F E+ ++ ++ER + + + N KE+K
Sbjct: 246 RMFRNEGVDTT-HNPEFTSIE----FYEAYSDLWGMMERTEGVFKHLMNKFNIKEVKFNG 300
Query: 271 FELNEPKKPFPRITYDEAL-------------EILSDLGKE--------IPWGEDIDTEG 309
F++ PF R+ +A+ E + +L K+ +G I+
Sbjct: 301 FDMTF-NFPFKRVNMIDAMSEKINVDIRKLNEEQMFELAKKHGIKIEKFFRYGHIINELF 359
Query: 310 EKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDL----EYRGVEISSG 365
EK + + ++E F+Y +P E P + +DK +A E+ +
Sbjct: 360 EKYVEETLMEPT-----FVYGHPIEISPTAAIDPDDKRFTTRAETFIGTKEFANMFTELN 414
Query: 366 GQREHRHDILVEQIREKGLNPESFEF---YLRAFEYGMPPHGGFGLGAERLIMRMLDIGN 422
+ + + ++ N E+ E ++ A EYGMPP GG G+G +R IM + +
Sbjct: 415 DPIDQLQRFENQLLEKENGNEEANEIDWDFVNALEYGMPPTGGSGMGIDRTIMTLTQNDS 474
Query: 423 IREVILFPR 431
IR+V+LFP+
Sbjct: 475 IRDVVLFPQ 483
>dbj|BAA35676.1| (D90730) Asparaginyl-tRNA synthetase (EC 6.1.1.22)
(asparagine-tRNA ligase) (asnRS). [Escherichia coli]
Length = 221
Score = 112 bits (278), Expect = 7e-24
Identities = 73/223 (32%), Positives = 112/223 (49%), Gaps = 20/223 (8%)
Query: 226 EAWSIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEP--------- 276
E W ++ E+AF + + L E ++ YV V E ++K +++
Sbjct: 1 EFWMLEPEVAFANLND-IAGLAEAMLKYVFKAVLEERADDMKFFAERVDKDAVSRLERFI 59
Query: 277 KKPFPRITYDEALEILSDLGKE----IPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYP 332
+ F ++ Y +A+ IL + G++ + WG D+ +E E+ Y+ E + YP
Sbjct: 60 EADFAQVDYTDAVTILENCGRKFENPVYWGVDLSSEHER----YLAEEHFKAPVVVKNYP 115
Query: 333 SEAKPFYIMKYEDKPEVCKAFDLEYRGV-EISSGGQREHRHDILVEQIREKGLNPESFEF 391
+ K FY+ ED V A D+ G+ EI G QRE R D+L E++ E GLN E + +
Sbjct: 116 KDIKAFYMRLNEDGKTVA-AMDVLAPGIGEIIGGSQREERLDVLDERMLEMGLNKEDYWW 174
Query: 392 YLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRR 434
Y YG PH GFGLG ERLI + + N+R+VI FPR R
Sbjct: 175 YRDLRRYGTVPHSGFGLGFERLIAYVTGVQNVRDVIPFPRTPR 217
>emb|CAA10905.1| (AJ222645) asparaginyl-tRNA synthetase [Arabidopsis thaliana]
Length = 276
Score = 111 bits (276), Expect = 1e-23
Identities = 76/271 (28%), Positives = 127/271 (46%), Gaps = 22/271 (8%)
Query: 176 FPLKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMA 235
F +F D +L S + + + S L KV+ GP F A++ + RHL E W+++ EMA
Sbjct: 6 FSKDFFGRDTYLTASGRFHLESYASA-LGKVYTFGPRFIADKIDNARHLAEKWNVETEMA 64
Query: 236 FIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEP---------KKPFPRITYD 286
F E ++ MD + ++ YV EN ++++K + +++ R +Y
Sbjct: 65 FAELDD-AMDCADEYFKFLCKYVLENRDEDMKFISKRVDKTITTRLEATASSSLLRFSYT 123
Query: 287 EALEIL-----SDLGKEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIM 341
E + +L + + WG + TE L + + ++ YP K FY+
Sbjct: 124 EVISLLQKATTTKFETKPEWGVALTTEHLSYLTDEIYKGP----VIVHTYPKAIKQFYVR 179
Query: 342 KYEDKPEVCKAFDLEYRGVEIS-SGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGM 400
+DK V AFDL V + +G Q E R +IL +I E G E FE+YL +G
Sbjct: 180 LNDDKKTVA-AFDLVVPKVGVVITGSQNEERFEILDARIGESGFTREKFEWYLDLRRHGT 238
Query: 401 PPHGGFGLGAERLIMRMLDIGNIREVILFPR 431
H G L E++++ + +I++ I FPR
Sbjct: 239 VKHSGISLSMEQMLLYATGLPDIKDAIPFPR 269
>gb|AAD46682.1|AF170910_1 (AF170910) SYNC2 protein [Arabidopsis thaliana]
Length = 638
Score = 111 bits (276), Expect = 1e-23
Identities = 76/271 (28%), Positives = 127/271 (46%), Gaps = 22/271 (8%)
Query: 176 FPLKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMA 235
F +F D +L S + + + S L KV+ GP F A++ + RHL E W+++ EMA
Sbjct: 368 FSKDFFGRDTYLTASGRFHLESYASA-LGKVYTFGPRFIADKIDNARHLAEKWNVETEMA 426
Query: 236 FIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEP---------KKPFPRITYD 286
F E ++ MD + ++ YV EN ++++K + +++ R +Y
Sbjct: 427 FAELDD-AMDCADEYFKFLCKYVLENRDEDMKFISKRVDKTITTRLEATASSSLLRFSYT 485
Query: 287 EALEIL-----SDLGKEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIM 341
E + +L + + WG + TE L + + ++ YP K FY+
Sbjct: 486 EVISLLQKATTTKFETKPEWGVALTTEHLSYLTDEIYKGP----VIVHTYPKAIKQFYVR 541
Query: 342 KYEDKPEVCKAFDLEYRGVEIS-SGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGM 400
+DK V AFDL V + +G Q E R +IL +I E G E FE+YL +G
Sbjct: 542 LNDDKKTVA-AFDLVVPKVGVVITGSQNEERFEILDARIGESGFTREKFEWYLDLRRHGT 600
Query: 401 PPHGGFGLGAERLIMRMLDIGNIREVILFPR 431
H G L E++++ + +I++ I FPR
Sbjct: 601 VKHSGISLSMEQMLLYATGLPDIKDAIPFPR 631
>gb|AAF02166.1|AC009853_26 (AC009853) putative asparaginyl-tRNA synthetase [Arabidopsis
thaliana]
Length = 638
Score = 111 bits (276), Expect = 1e-23
Identities = 76/271 (28%), Positives = 127/271 (46%), Gaps = 22/271 (8%)
Query: 176 FPLKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMA 235
F +F D +L S + + + S L KV+ GP F A++ + RHL E W+++ EMA
Sbjct: 368 FSKDFFGRDTYLTASGRFHLESYASA-LGKVYTFGPRFIADKIDNARHLAEKWNVETEMA 426
Query: 236 FIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEP---------KKPFPRITYD 286
F E ++ MD + ++ YV EN ++++K + +++ R +Y
Sbjct: 427 FAELDD-AMDCADEYFKFLCKYVLENRDEDMKFISKRVDKTITTRLEATASSSLLRFSYT 485
Query: 287 EALEIL-----SDLGKEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIM 341
E + +L + + WG + TE L + + ++ YP K FY+
Sbjct: 486 EVISLLQKATTTKFETKPEWGVALTTEHLSYLTDEIYKGP----VIVHTYPKAIKQFYVR 541
Query: 342 KYEDKPEVCKAFDLEYRGVEIS-SGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGM 400
+DK V AFDL V + +G Q E R +IL +I E G E FE+YL +G
Sbjct: 542 LNDDKKTVA-AFDLVVPKVGVVITGSQNEERFEILDARIGESGFTREKFEWYLDLRRHGT 600
Query: 401 PPHGGFGLGAERLIMRMLDIGNIREVILFPR 431
H G L E++++ + +I++ I FPR
Sbjct: 601 VKHSGISLSMEQMLLYATGLPDIKDAIPFPR 631
>pir||T04993 probable aspartate--tRNA ligase (EC 6.1.1.12) T16L1.250 -
Arabidopsis thaliana >gi|3549678|emb|CAA20589.1|
(AL031394) putative aspartate--tRNA ligase [Arabidopsis
thaliana] >gi|7270325|emb|CAB80093.1| (AL161584)
putative aspartate--tRNA ligase [Arabidopsis thaliana]
Length = 636
Score = 110 bits (273), Expect = 3e-23
Identities = 95/300 (31%), Positives = 146/300 (48%), Gaps = 50/300 (16%)
Query: 3 RTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKL 62
RT E++ GK+V + GWV + GG+ F+ +RD GIVQV + P E L
Sbjct: 75 RTELCGELSVNDVGKRVHLCGWVALHRVHGGLTFLNLRDHTGIVQVRTLPDEFP-EAHGL 133
Query: 63 IPKLNSEDVIVVEGIVNFTP------KAKLGF-EIIPEKLEVISKAKTPLPLDPT----G 111
I + E V++VEG V P K K GF E++ E +E+++ +T LP T
Sbjct: 134 INDMRLEYVVLVEGTVRSRPNESVNKKMKTGFVEVVAEHVEILNPVRTKLPFLVTTADEN 193
Query: 112 KVKAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFY-KEGFIEIHTPKIIATATE 170
K + + RL R +DLR ++ + +R +V + R + + GFIE T
Sbjct: 194 KDLIKEEIRLRFRCLDLRRQQMKNNIVLRHNVVKLIRRYLEDRHGFIESGT--------- 244
Query: 171 GGTELFPLKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSI 230
++ L QSPQL+KQM+M +G DK ++I FR E+ R E +
Sbjct: 245 ---------FYA----LPQSPQLFKQMLMVSGFDKYYQIARCFRDEDLRADRQ-PEFTQL 290
Query: 231 DAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALE 290
D EMAF+ E+++ L E LI V + E+K ++ PFPR+TY +A++
Sbjct: 291 DMEMAFMPM-EDMLKLNEDLIRKVFS--------EIKGIQL-----PDPFPRLTYADAMD 336
>emb|CAB89697.1| (AJ276418) putative lysyl tRNA synthetase [Xanthomonas campestris
pv. campestris]
Length = 505
Score = 110 bits (272), Expect = 4e-23
Identities = 124/476 (26%), Positives = 208/476 (43%), Gaps = 63/476 (13%)
Query: 2 LRTHYSSEITEELN-------------GKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQV 48
+RTH++ ++ E + VK+AG + + +G F I+D G VQ+
Sbjct: 40 VRTHFAGDLQAEFAEAETWTAEALEAADRSVKLAGRLMAKRVMGKASFAQIQDESGRVQL 99
Query: 49 TAPKKKVPQEIFKLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLD 108
+ V + + + D++ VEG + T +L + L +++K+ PLP
Sbjct: 100 FL-QGNVLGDAYTAFKGWDVGDIVAVEGGLTRTKTGELSVKATA--LRLLTKSLRPLPDK 156
Query: 109 PTGKVKAELDTRLDNRFMDLR-NPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIAT 167
G ++++ R R++DL P +F RS + RA R + F+E+ TP +
Sbjct: 157 WHGL--SDVEQRYRQRYVDLIVTPEAREVFIKRSKIIRAIRAWLDARRFLEVETPMM--H 212
Query: 168 ATEGGTELFPLKYFEN----DAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRH 223
GG P N D +L +P+LY + ++ GL++V+EI FR E +TRH
Sbjct: 213 YIPGGATAKPFTTHHNALDLDLYLRVAPELYLKRLVVGGLERVYEINRNFR-NEGVSTRH 271
Query: 224 LNEAWSIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRI 283
E ++ A+ + E+MDL E++I V + + +L F R
Sbjct: 272 NPEFTMLELYEAY-ATYHEIMDLTEQVIRDTAQGVLGTTQVSWDGADIDL---APAFRRW 327
Query: 284 TYDEALEILSDLGKEIPWGEDIDTEG-----EKL---------LGKYML-------ENEG 322
DEA+ EI + D E+L GK +L E+
Sbjct: 328 RMDEAVR---HHNPEISAADCTDRAALLRHCERLKIKVKPSYGWGKLLLEIFESTVEHTL 384
Query: 323 AELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSG----GQREHRHDILVEQ 378
+ FI +P E P + +P F+L G E+++G E + Q
Sbjct: 385 VQPTFITDHPVEVSPL-ARASDTEPGYTDRFELFINGKELANGFSELNDPEDQAARFQAQ 443
Query: 379 IREK-GLNPESFEF---YLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFP 430
++ K G + E+ + Y+RA EYGM P GG G+G +RL+M + +IR+V+LFP
Sbjct: 444 VQAKDGGDDEAMHYDADYIRALEYGMAPTGGLGIGIDRLVMLLTGSTSIRDVLLFP 499
>sp|Q9KU60|SYK_VIBCH LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|11271287|pir||A82296 lysyl-tRNA synthetase, heat
inducible VC0664 [imported] - Vibrio cholerae (group O1
strain N16961) >gi|9655101|gb|AAF93829.1| (AE004152)
lysyl-tRNA synthetase, heat inducible [Vibrio cholerae]
Length = 512
Score = 109 bits (271), Expect = 5e-23
Identities = 125/463 (26%), Positives = 202/463 (42%), Gaps = 53/463 (11%)
Query: 7 SSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKL 66
S E E LN V +AG V + F+ I++ G +Q A K+V QE+ L
Sbjct: 64 SKEELEALN-HVVSIAGRVMAKRG----PFLVIQETSGRIQAYA-SKEVQQELKDKYQGL 117
Query: 67 NSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFM 126
+ D+I V+G ++ + K L + E+ ++++KA PLP G E+ R R++
Sbjct: 118 DIGDIIGVQGALHKSGKGDLYVNM--EQFQLLTKALRPLPEKFHGLTDQEM--RYRQRYV 173
Query: 127 DLR-NPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFEN-- 183
DL N + F +RS V A R F + F+E+ TP + GG P N
Sbjct: 174 DLIVNENSRNAFIVRSKVMSAIRNFMISKQFMEVETPMM--HVIPGGASARPFITHHNAL 231
Query: 184 --DAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEE 241
+L +P+LY + ++ G D+VFEI FR E + RH E ++ MA+ + +
Sbjct: 232 DMPMYLRIAPELYLKRLVVGGFDRVFEINRNFR-NEGLSPRHNPEFTMMEFYMAYAD-YK 289
Query: 242 EVMDLLERLILYVI------------NYVRENNEKELKILEFELNEPKKP----FPRITY 285
++MDL E L+ V + E K ++ F+ + P +T
Sbjct: 290 DLMDLTEELLSSVALEVLGSTSMPYGEHTVEFGGKYARMSMFDAIKHYNPNHAQIQALTE 349
Query: 286 DEALEILSDLGKEIPWGEDIDTEGEKLLGKYMLENEG-------AELYFIYRYPSEAKPF 338
++ DL I +D E G+ + E G + FI YP++ P
Sbjct: 350 EDIQN--RDLMVSIAKSVHVDVEPFWTCGQLLEEIFGETAEPKLMQPTFITGYPADISPL 407
Query: 339 YIMKYEDKPEVCKAFDLEYRGVEISSG----GQREHRHDILVEQIREKGLNPESFEF--- 391
+ +D P F+ G E+++G E + Q+ K + F
Sbjct: 408 -ARRSDDNPFFTDRFEFFIGGREVANGFSELNDAEDQDARFKAQVEAKESGDDEAMFYDA 466
Query: 392 -YLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDR 433
Y+ A E+G+PP G G+G +RL+M + + IR+VILFP R
Sbjct: 467 DYITALEHGLPPTAGQGIGIDRLVMLLTNTHTIRDVILFPAMR 509
>gb|AAF53577.2| (AE003652) CG17938 gene product [Drosophila melanogaster]
Length = 1160
Score = 107 bits (264), Expect = 3e-22
Identities = 92/298 (30%), Positives = 145/298 (47%), Gaps = 31/298 (10%)
Query: 3 RTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKL 62
RTH E+T +KV + GW+ E + + KF +RD G QV K E +
Sbjct: 483 RTHNCGELTSNDINEKVVICGWL-EFQRMN--KFFILRDAYGQTQVLLSPKTYGLEEYAE 539
Query: 63 IPKLNSEDVIVVEGIV------NFTPKAKLGF-EIIPEKLEVISKAKTPLPLDPTGKVKA 115
+ E ++ VEG V PK + G E+ +K+ V++ AK LP + +A
Sbjct: 540 TG-VPIESIVRVEGTVIPRPAATINPKMQTGHVEVEADKVVVLNPAKKNLPFEIRKFNRA 598
Query: 116 ELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKE-GFIEIHTPKIIATATEGGTE 174
RL +R++DLR + ++RS+V RE+ GF+E+ TP + T GG +
Sbjct: 599 GERLRLTHRYLDLRFNDMQHNLRLRSAVIMKMREYLINYLGFVEVETPTLFRR-TPGGAQ 657
Query: 175 LF--PLKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDA 232
F P + + L QSPQ +KQM+MS G+D+ F++ +R E R E +D
Sbjct: 658 EFVVPTRKAGHFYSLVQSPQQFKQMLMSGGIDRYFQVARCYRDEATRPDRQ-PEFTQLDI 716
Query: 233 EMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALE 290
E++F S +++M L+E + Y + K+ L+ PF RITY+EA+E
Sbjct: 717 ELSF-TSRDDIMQLIEETLRY-------SWPKDFPRLQ-------TPFRRITYEEAME 759
>sp|P47382|SYK_MYCGE LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|1361711|pir||A64215 lysine--tRNA ligase (EC 6.1.1.6)
- Mycoplasma genitalium >gi|3844726|gb|AAC71353.1|
(U39693) lysyl-tRNA synthetase (lysS) [Mycoplasma
genitalium]
Length = 490
Score = 106 bits (261), Expect = 7e-22
Identities = 120/458 (26%), Positives = 205/458 (44%), Gaps = 57/458 (12%)
Query: 12 EELNGKK-VKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSED 70
EEL K V +AG + ++ F+ I+D +G VQ+ KK P+ ++ D
Sbjct: 51 EELKKKATVSLAGRIIAIRQT----FLIIQDFDGQVQLYINKKIHPKLFDYFNEFVDIGD 106
Query: 71 VIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLR- 129
IVV G T L + E++++I+K P G +++TR RF+DL
Sbjct: 107 QIVVSGKPMLTKTKVLTLAV--EEMKIIAKCLLVPPEKWHGLT--DIETRARKRFLDLTY 162
Query: 130 NPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFEN----DA 185
N + +F R+ + ++ R F + GFIE+ TP + A GG P K N D
Sbjct: 163 NLAMRDVFLKRTKIIKSIRSFLDQNGFIEVETPTLQAVL--GGANAKPFKTHYNALKADF 220
Query: 186 FLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMD 245
+L + ++ + ++ G +KV+E+G +FR E +TT H E SI+ A+ + E ++
Sbjct: 221 YLRIANEIALKKLIIGGFNKVYEMGKMFRNEGVDTT-HNPEFTSIEIYQAYADFEVMLV- 278
Query: 246 LLERLILYVINYVREN----NEKELKILEFELNEPKKPFPRITYDEALEILSDLG-KEIP 300
L+E+LI + + + N K + + K PF +IT E ++ ++ + +
Sbjct: 279 LVEKLIQSLCESLNQFSFNWNNKTINL--------KTPFHKITMVELIKKVTGIDFNSVK 330
Query: 301 WGEDIDTEGEK-----------------LLGKYMLENEGAELYFIYRYPSEAKPFYIMKY 343
+ EK L + E E F+ YP P +
Sbjct: 331 DDQSAILLAEKHHVKLAKHQQNKQHIINLFFEQFCEQTLIEPTFVTHYPKAVSPL-AKQD 389
Query: 344 EDKPEVCKAFDLEYRGVEISSGGQREH----RHDILVEQIREKGL-NPESFEF---YLRA 395
PE + F+L G EI++ + + +Q+ EK L N E+ E +L A
Sbjct: 390 PSNPEFTQRFELFINGKEIANAYSELNDPLEQRKRFEQQLEEKQLGNDETSELDESFLEA 449
Query: 396 FEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDR 433
+GM G G+G +RL+M + + +IR+V+ FP+ R
Sbjct: 450 LSFGMVNTAGLGIGIDRLVMLLCECNSIRDVVFFPQLR 487
>pir||S70779 asparagine--tRNA ligase (EC 6.1.1.22) - Xenorhabdus nematophilus
(fragment)
Length = 192
Score = 99.1 bits (243), Expect = 9e-20
Identities = 59/160 (36%), Positives = 86/160 (52%), Gaps = 10/160 (6%)
Query: 280 FPRITYDEALEILSDLGKEIP----WGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEA 335
F ++ Y +A++IL + G++ WG D+ +E E+ Y+ E + YP
Sbjct: 27 FIQLDYTDAIKILENCGQKFENPYFWGVDLSSEHER----YLAEKHFEAPVIMKNYPKNI 82
Query: 336 KPFYIMKYEDKPEVCKAFDLEYRGV-EISSGGQREHRHDILVEQIREKGLNPESFEFYLR 394
K FY+ ED V A D+ G+ EI G QRE R D+L +++ E GLN E + +Y
Sbjct: 83 KAFYMRMNEDGKTVA-AMDVLAPGIGEIIGGSQREERLDMLDKRLEEMGLNKEDYWWYRD 141
Query: 395 AFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRR 434
YG PH GFGLG ERL+ + + N+R+VI FPR R
Sbjct: 142 LRRYGTVPHAGFGLGFERLVAYVTGVANVRDVIPFPRTPR 181
>dbj|BAA99139.1| (AP002548) lysyl tRNA synthetase [Chlamydophila pneumoniae J138]
Length = 527
Score = 97.9 bits (240), Expect = 2e-19
Identities = 117/477 (24%), Positives = 216/477 (44%), Gaps = 60/477 (12%)
Query: 7 SSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVP----QEIFKL 62
+SE + +V+ AG + + +G F I D +QV ++ E ++
Sbjct: 55 NSEAAMSRSTPRVRFAGRLVLFRAMGKNAFGQILDHNQTIQVMFNREFTSVHGLSEDAEI 114
Query: 63 IP------KLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAE 116
P KL+ D++ ++G + FT +L ++ E + ++ K+ LP G ++
Sbjct: 115 TPIKFIEKKLDLGDILGIDGYLFFTHSGEL--TVLVETVTLLCKSLLSLPDKHAGL--SD 170
Query: 117 LDTRLDNRFMDLRNPRVMS-IFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTEL 175
+ R R++DL + R +S F RS + + R + GF+E+ TP I GG E
Sbjct: 171 KEVRYRKRWLDLISSREVSDTFVKRSYIIKLIRNYMDAHGFLEVETP--ILQNIYGGAEA 228
Query: 176 FP----LKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSID 231
P ++ ++ FL S ++ + ++ G +++E+G +FR E + T H E I+
Sbjct: 229 KPFTTTMEALHSETFLRISLEIALKKILVGGAPRIYELGKVFRNEGIDRT-HNPEFTMIE 287
Query: 232 AEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEP-----KKPFPRITYD 286
A A+++ +EVM +E L+ +++ V N++ + + + P K P+ R+T
Sbjct: 288 AYAAYMD-YKEVMVFVENLVEHLVRAV--NHDNTSLVYSYWKHGPQEVDFKAPWIRMTMK 344
Query: 287 EAL--------EILSD------LGKEIPWGEDIDTEGEK------LLGKYMLENEGAELY 326
E++ ++ SD L K+ + E + L + + +N A +
Sbjct: 345 ESIATYAGIDVDVHSDQKLKEILKKKTTFPETAFATASRGMLIAALFDELVSDNLIAP-H 403
Query: 327 FIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEI----SSGGQREHRHDILVEQIREK 382
I +P E P + F+ G E+ S + ++L +Q +K
Sbjct: 404 HITDHPVETTPLCKTLRSGDTAFVERFESFCLGKELCNAYSELNDPIRQRELLEQQHTKK 463
Query: 383 GLNPES-----FEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRR 434
L P+S E +L A GMPP GGFG+G +RL+M + + +IR+V+ FP RR
Sbjct: 464 ELLPDSECHPIDEEFLEALCQGMPPAGGFGIGVDRLVMILTNAASIRDVLYFPVMRR 520
>sp|Q9Z6X5|SYK_CHLPN LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|7437608|pir||E72016 lysine--tRNA ligase (EC 6.1.1.6)
[similarity] - Chlamydophila pneumoniae (strains CWL029
and AR39) >gi|4377254|gb|AAD19069.1| (AE001673) Lysyl
tRNA Synthetase [Chlamydophila pneumoniae CWL029]
>gi|7189844|gb|AAF38715.1| (AE002251) lysyl-tRNA
synthetase [Chlamydophila pneumoniae AR39]
Length = 527
Score = 97.5 bits (239), Expect = 3e-19
Identities = 117/477 (24%), Positives = 216/477 (44%), Gaps = 60/477 (12%)
Query: 7 SSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVP----QEIFKL 62
+SE + +V+ AG + + +G F I D +QV ++ E ++
Sbjct: 55 NSEAAMSRSTPRVRFAGRLVLFRAMGKNAFGQILDHNQTIQVMFNREFTSVHGLSEDAEI 114
Query: 63 IP------KLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAE 116
P KL+ D++ ++G + FT +L ++ E + ++ K+ LP G ++
Sbjct: 115 TPIKFIEKKLDLGDILGIDGYLFFTHSGEL--TVLVETVTLLCKSLLSLPDKHAGL--SD 170
Query: 117 LDTRLDNRFMDLRNPRVMS-IFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTEL 175
+ R R++DL + R +S F RS + + R + GF+E+ TP I GG E
Sbjct: 171 KEVRYRKRWLDLISSREVSDTFVKRSYIIKLIRNYMDAHGFLEVETP--ILQNIYGGAEA 228
Query: 176 FP----LKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSID 231
P ++ ++ FL S ++ + ++ G +++E+G +FR E + T H E I+
Sbjct: 229 KPFTTTMEALHSEMFLRISLEIALKKILVGGAPRIYELGKVFRNEGIDRT-HNPEFTMIE 287
Query: 232 AEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEP-----KKPFPRITYD 286
A A+++ +EVM +E L+ +++ V N++ + + + P K P+ R+T
Sbjct: 288 AYAAYMD-YKEVMVFVENLVEHLVRAV--NHDNTSLVYSYWKHGPQEVDFKAPWIRMTMK 344
Query: 287 EAL--------EILSD------LGKEIPWGEDIDTEGEK------LLGKYMLENEGAELY 326
E++ ++ SD L K+ + E + L + + +N A +
Sbjct: 345 ESIATYAGIDVDVHSDQKLKEILKKKTTFPETAFATASRGMLIAALFDELVSDNLIAP-H 403
Query: 327 FIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEI----SSGGQREHRHDILVEQIREK 382
I +P E P + F+ G E+ S + ++L +Q +K
Sbjct: 404 HITDHPVETTPLCKTLRSGDTAFVERFESFCLGKELCNAYSELNDPIRQRELLEQQHTKK 463
Query: 383 GLNPES-----FEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRR 434
L P+S E +L A GMPP GGFG+G +RL+M + + +IR+V+ FP RR
Sbjct: 464 ELLPDSECHPIDEEFLEALCQGMPPAGGFGIGVDRLVMILTNAASIRDVLYFPVMRR 520
>pir||T41563 hypothetical protein SPCC736.06 - fission yeast
(Schizosaccharomyces pombe) >gi|3845470|emb|CAA19270.1|
(AL023705) aspartyl-trna synthetase [Schizosaccharomyces
pombe]
Length = 611
Score = 96.0 bits (235), Expect = 8e-19
Identities = 83/308 (26%), Positives = 141/308 (44%), Gaps = 51/308 (16%)
Query: 14 LNGKKVKVAGWV-------------QEVKDLGGI--------KFIWIRDREGIVQVTAPK 52
L G KV + GW+ +++D G K I + RE +V T
Sbjct: 13 LVGTKVSIQGWLVATSRQVSKSISFHQLRDTHGTILQLLSTDKIILQQKREPLVSSTDFS 72
Query: 53 KKVPQEIFKLIPKLNSEDVIVVEGIVNFTPKAKLG----FEIIPEKLEVISKAKTPLPLD 108
++ + + + + E V+ V G + P+ FE+ E +++++ AK L L
Sbjct: 73 QQKSTSVMRTLSSIPPESVVQVTGKLQRRPEHDRRPGNEFELHVEDVKLLNVAKN-LQLF 131
Query: 109 PTGKVKAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATA 168
P G K + +L NR + LR P+ S + RS + FF F E+ TP + +
Sbjct: 132 P-GDEKPGMRIQLANRHIQLRAPKYNSYLRQRSRLAYQVHSFFNDREFCEVETPLLFKST 190
Query: 169 TEGGTE------LFPLKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTR 222
EG E L P K++ L QSPQ YKQ++M++G+ ++I FR E+ R
Sbjct: 191 PEGAREFVVPSRLNPGKFYA----LPQSPQQYKQILMASGIGNYYQIARCFRDEDLRFDR 246
Query: 223 HLNEAWSIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPR 282
E ID EM+F++ E+M+++E L++ ++++ K + + KPF
Sbjct: 247 Q-PEFTQIDLEMSFVDKPHEIMEVVEDLLVRLVSFA-----KGITL--------AKPFQH 292
Query: 283 ITYDEALE 290
ITY A++
Sbjct: 293 ITYQHAID 300
>pir||E70155 aspartate--tRNA ligase (EC 6.1.1.12) aspS - Lyme disease spirochete
>gi|2688349|gb|AAB91506.1| (AE001149) aspartyl-tRNA
synthetase (aspS) [Borrelia burgdorferi]
Length = 506
Score = 91.3 bits (223), Expect = 2e-17
Identities = 61/204 (29%), Positives = 99/204 (47%), Gaps = 18/204 (8%)
Query: 88 FEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRAT 147
FEI+ + +E+ISK LP A +++L+ R++DLR + + +R
Sbjct: 11 FEILAKNIEIISKCNE-LPFMIEDDNNASENSKLEYRYLDLRRDSLKNKIILRCQATHLI 69
Query: 148 REFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFLA--QSPQLYKQMMMSTGLDK 205
R F K F+E+ TP + + EG + +F A QSPQLYKQ++M G DK
Sbjct: 70 RNFLIKRKFLELETPTFVKSTPEGARDFVIPSRIHKGSFYALPQSPQLYKQLIMIAGFDK 129
Query: 206 VFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKE 265
F+I +R E+ R E +D EM+F++ +E + L+E ++ +
Sbjct: 130 YFQIARCYRDEDSRGDRQ-PEFTQLDLEMSFVK-KENIFKLIENMLFLIFKNC------- 180
Query: 266 LKILEFELNEPKKPFPRITYDEAL 289
+N PKK F +ITY +A+
Sbjct: 181 -----ININLPKK-FKKITYKKAM 198
Score = 69.1 bits (166), Expect = 1e-10
Identities = 39/103 (37%), Positives = 56/103 (53%), Gaps = 6/103 (5%)
Query: 336 KPFYIMKYEDKPE--VCKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPES----F 389
K YI E P+ + + +DL GVE+ SG R H ++ + G E F
Sbjct: 373 KKQYIANLEKNPKKTIGEIYDLVLNGVELGSGSIRIHNKELQQRIFKIIGFQKEKSEDRF 432
Query: 390 EFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRD 432
F+L+A EYG P HGG +G +RLIM M +I++VILFP++
Sbjct: 433 GFFLKALEYGAPNHGGIAIGIDRLIMLMTKSTSIKDVILFPKN 475
>pir||S77842 probable asparagine--tRNA ligase (EC 6.1.1.22) - Mycoplasma
capricolum (fragment) >gi|530408|emb|CAA83705.1|
(Z33026) Asn-tRNA synthetase [Mycoplasma capricolum]
Length = 172
Score = 89.3 bits (218), Expect = 8e-17
Identities = 60/167 (35%), Positives = 85/167 (49%), Gaps = 14/167 (8%)
Query: 280 FPRITYDEALEILSDLG--------KEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRY 331
F TY EA+EIL +I +G D+ TE E+ Y+ E F+ Y
Sbjct: 10 FKVTTYTEAIEILKQAVANGHKFEVSDIEFGLDLGTEHER----YICEQVNKAPTFVTNY 65
Query: 332 PSEAKPFYIMKYEDKPEVCKAFDLEYRGV-EISSGGQREHRHDILVEQIREKGLNPESFE 390
P E K FY+ + ED V A DL G+ E+ G QRE ++ L+++ +E ++ + E
Sbjct: 66 PKEIKAFYMKQNEDNKTVA-AVDLLVPGIGELVGGSQREDNYEKLIKRCKEVNIDIDQLE 124
Query: 391 FYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRRRLV 437
+Y YG GFGLG ERLIM + NIR+VI FPR + L+
Sbjct: 125 WYNNLRLYGYYKSAGFGLGFERLIMYITGASNIRDVIPFPRTPKNLL 171
>gi|6325153 Aspartyl-tRNA synthetase, mitochondrial; Msd1p [Saccharomyces
cerevisiae] >gi|135101|sp|P15179|SYDM_YEAST
ASPARTYL-TRNA SYNTHETASE, MITOCHONDRIAL (ASPARTATE--TRNA
LIGASE) (ASPRS) >gi|2144551|pir||SYBYDM aspartate--tRNA
ligase (EC 6.1.1.12), mitochondrial - yeast
(Saccharomyces cerevisiae) >gi|172872|gb|AAA35137.1|
(M26020) aspartyl-tRNA synthetase [Saccharomyces
cerevisiae] >gi|173036|gb|AAA35173.1| (M24418)
mitochondrial aspartyl-tRNA synthetase [Saccharomyces
cerevisiae] >gi|1151223|gb|AAB68196.1| (U43281) Msd1p
[Saccharomyces cerevisiae]
Length = 658
Score = 88.5 bits (216), Expect = 1e-16
Identities = 78/256 (30%), Positives = 126/256 (48%), Gaps = 37/256 (14%)
Query: 15 NGKKVKVAGWVQEVKDLGGIKFIW--IRDREG-IVQVTAPKKKVPQEIFKLIPKLNSEDV 71
+G+K+ + GW+++ G I+ +RD G I+Q+ K L+ EDV
Sbjct: 46 SGQKIVLNGWIEQKPKRVGKNLIFGLLRDSNGDIIQLVDNKS--------LLKGFTLEDV 97
Query: 72 IVVEGIVNFTPKAKLGFEIIPE---KLEVISKAKTPLPLDPTGKVKAEL-DTRL------ 121
+ GI++ K KL E E +LE I+ L+ + K A++ D +L
Sbjct: 98 VQAVGILSL--KRKLSNEDADEYEVQLEDITV------LNASNKKPAQMQDFKLSAIYPP 149
Query: 122 DNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTE-LFPLKY 180
+ R++ LRNP+ K RSS+ + R F F E+ TP + EG E L P +
Sbjct: 150 EFRYLQLRNPKYQDFLKKRSSISKEIRNSFNNFDFTEVETPMLFKATPEGAREFLVPTRT 209
Query: 181 FENDA-----FLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMA 235
+D L QSPQ YKQ++M++G++K +++ FR E+ R E +D EMA
Sbjct: 210 KRSDGKPSFYALDQSPQQYKQLLMASGVNKYYQMARCFRDEDLRADRQ-PEFTQVDMEMA 268
Query: 236 FIESEEEVMDLLERLI 251
F S E+VM ++E+ +
Sbjct: 269 FANS-EDVMKIIEKTV 283
>dbj|BAA90843.1| (AB031211) LysS [Bacillus halodurans]
Length = 310
Score = 84.7 bits (206), Expect = 2e-15
Identities = 87/319 (27%), Positives = 146/319 (45%), Gaps = 49/319 (15%)
Query: 155 GFIEIHTPKIIATATEGGTELFPLKYFEN----DAFLAQSPQLYKQMMMSTGLDKVFEIG 210
G++E+ TP + + GG P N ++ + +L+ + ++ G++KV+EIG
Sbjct: 3 GYLEVETPTM--HSIPGGASARPFVTHHNALDMTLYMRIAIELHLKRLIVGGMEKVYEIG 60
Query: 211 PIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILE 270
+FR E +TRH E I+ A+ + + +M+L E LI ++ V + E
Sbjct: 61 RVFR-NEGVSTRHNPEFTMIELYEAYADYND-IMELTELLIAHIAKDVLGTTT--ITYGE 116
Query: 271 FELN-EPKKPFPRITYDEALEILSDLGKEIPWGEDIDTEGEKLLGKY------------- 316
E+N EPK + R+ EA++ + G + W E D E L ++
Sbjct: 117 HEVNLEPK--WRRVHMVEAIK--EETGVDF-WNEMSDEEARALAKEHNVPVKETMTYGHV 171
Query: 317 -------MLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSG---- 365
+E + + F+Y +P P K D P F+L G E ++
Sbjct: 172 VNEFFEHFVEEKLIQPTFVYGHPVAISPL-AKKNPDDPRFTDRFELFIVGREHANAFSEL 230
Query: 366 ----GQREHRHDILVEQIREKGLNPESF--EFYLRAFEYGMPPHGGFGLGAERLIMRMLD 419
QR LVE RE+G + E ++ + EYGMPP GG G+G +RL+M + +
Sbjct: 231 NDPIDQRHRFEQQLVE--REQGDDEAHMMDEDFVESLEYGMPPTGGLGIGIDRLVMLLTN 288
Query: 420 IGNIREVILFPRDRRRLVP 438
+IR+V+LFP+ R + P
Sbjct: 289 SPSIRDVLLFPQMRHKDSP 307
>sp|Q56112|SYN_SALTI ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRNA LIGASE) (ASNRS)
>gi|1435180|emb|CAA61904.1| (X89757) asparaginyl-tRNA
synthetase [Salmonella typhi]
Length = 109
Score = 83.1 bits (202), Expect = 6e-15
Identities = 48/105 (45%), Positives = 60/105 (56%), Gaps = 2/105 (1%)
Query: 331 YPSEAKPFYIMKYEDKPEVCKAFDLEYRGV-EISSGGQREHRHDILVEQIREKGLNPESF 389
YP E K FY+ ED V A D+ G+ EI G QRE R D+L ++ E GLN E +
Sbjct: 2 YPKEIKAFYMRLNEDGKTVA-AMDVLAPGIGEIIGGSQREERLDVLDARMAEMGLNKEDY 60
Query: 390 EFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRR 434
+Y YG PH GFGLG ERLI + + N+R+VI FPR R
Sbjct: 61 WWYSDLRRYGTVPHSGFGLGFERLIAYVTGVQNVRDVIPFPRTPR 105
>pir||C75215 asparaginyl-tRNA synthetase related protein PAB2356 - Pyrococcus
abyssi (strain Orsay) >gi|5457679|emb|CAB49170.1|
(AJ248283) asparaginyl-tRNA synthetase related protein
[Pyrococcus abyssi]
Length = 294
Score = 75.3 bits (182), Expect = 1e-12
Identities = 76/252 (30%), Positives = 113/252 (44%), Gaps = 44/252 (17%)
Query: 187 LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTT--RHLNEAWSIDAEMAFIESEEEVM 244
L S L+KQ+ ++ GL+K+F + P R E RH E +D E+ + ++ VM
Sbjct: 72 LTHSMILHKQLAIAMGLEKIFVLSPNIRLESRRKDDGRHSYEFTQLDFEIEGAKMKD-VM 130
Query: 245 DLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIPWGED 304
L+E LI + E +E FPR + + + D+ +E E
Sbjct: 131 RLIEELIYGLFRKAEEWTGRE--------------FPRARHFKVYDY-KDILEEFGSDEK 175
Query: 305 IDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPE--VCKAFDL--EYRGV 360
E E E ++I P E FY D+ E V K +DL Y
Sbjct: 176 ASMEME-------------EPFWIVNIPRE---FY-----DREENGVWKNYDLILPYGYG 214
Query: 361 EISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYG-MPPHGGFGLGAERLIMRMLD 419
E+SSGG+RE ++ +V +IR GL +SF YL G + P G G+G ERL+ ++
Sbjct: 215 EVSSGGEREWEYEKIVAKIRAAGLKEDSFRPYLEIARAGKLKPSAGAGIGVERLVRFIVG 274
Query: 420 IGNIREVILFPR 431
+I EV FPR
Sbjct: 275 AKHIAEVQPFPR 286
>pir||E82050 lysyl-tRNA synthetase-related protein VC2655 [imported] - Vibrio
cholerae (group O1 strain N16961)
>gi|9657247|gb|AAF95796.1| (AE004331) lysyl-tRNA
synthetase-related protein [Vibrio cholerae]
Length = 349
Score = 71.4 bits (172), Expect = 2e-11
Identities = 88/326 (26%), Positives = 148/326 (44%), Gaps = 40/326 (12%)
Query: 134 MSIFKIRSSVFRATREFFYKEGFIEIHTPKII-ATATEGGTELFPLK-----YFENDAF- 186
+S K R+++ R REFF + +E+ TP + AT T+ F + Y + A
Sbjct: 37 ISQLKQRATLLRQIREFFAERNVLEVETPAMSHATVTDIHLHTFKTEFVGPGYAKGSALH 96
Query: 187 LAQSPQLYKQMMMSTGLDKVFEIGPIFRAEE----HNTTRHLNEAWSIDAEMAFIESEEE 242
L SP+ + + +++ G ++++G FR EE HN + E + I + + E
Sbjct: 97 LMTSPEFHMKRLLAAGSGCIYQLGKAFRNEENGRYHNPEFTMLEWYRIGFDHHALMDE-- 154
Query: 243 VMDLLERLILYVINYVREN-NEKELKILEF-ELNEPKKPFPRITYDEALEILSDLGKEIP 300
MD L +L+L + R E L +L L E + ++ A LSD+ +
Sbjct: 155 -MDALLQLVLRCGSAERMTYQEAFLNVLGVCPLEEEMRELKQVA---ATLGLSDIAEP-- 208
Query: 301 WGEDIDTEGEKLLGKYMLENEGAELY--FIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYR 358
ED DT + LL +E + ++ F+Y +P+ + D P V F++ ++
Sbjct: 209 -EEDRDTLLQ-LLFSIGIEPKIGQITPAFVYDFPASQAALAKINPAD-PRVADRFEVYFK 265
Query: 359 GVEISSGGQREHRHDILVEQIR----------EKGLNPESFEFYL-RAFEYGMPPHGGFG 407
G+E+++G H D EQ+ E GL + +++L A E G+P G
Sbjct: 266 GIELANGF---HELDNPAEQLARFKADNAKRLEMGLTEQPIDYHLIAALEAGLPECAGVA 322
Query: 408 LGAERLIMRMLDIGNIREVILFPRDR 433
LG +RLIM L +I +V FP R
Sbjct: 323 LGIDRLIMLALGEDHIDKVTAFPFPR 348
>sp|Q9Z614|SYK3_BUCAP PUTATIVE LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS) (GX)
>gi|4378708|gb|AAD19636.1| (AF108665) lysyl-tRNA
synthetase homolog [Buchnera aphidicola]
Length = 324
Score = 70.2 bits (169), Expect = 4e-11
Identities = 76/325 (23%), Positives = 149/325 (45%), Gaps = 49/325 (15%)
Query: 140 RSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPL--KYF-------ENDAFLAQS 190
RS + R FF K+ +E+ TP I++ + L P YF + + +L S
Sbjct: 17 RSKIIADIRSFFLKKNIMEVETP-ILSQSGVTDVNLMPFITNYFSFNDNIKKKNLWLITS 75
Query: 191 PQLYKQMMMSTGLDKVFEIGPIFRAEE----HNTTRHLNEAWSIDAEMAFIESEEEVMDL 246
P+ + + ++S G +++I FR +E HN + E + + M E++++
Sbjct: 76 PEYHMKRLLSAGSGSIYQICRSFRNQEFGQYHNPEFTMLEWYQLSCSM------EKMIEE 129
Query: 247 LERLILYVINYVRENN-------EKELKI--LEFELNEPKKPFPRITYDEALEILSDLGK 297
++ ++N+ + + K LKI L L+E + + + + + +DL +
Sbjct: 130 IDFFFQKILNFNKADKISYQEVFMKFLKIDPLSTSLSELFQCYKKFNLKNLIYLENDLNQ 189
Query: 298 EIPWGEDIDT-EGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLE 356
I E+I T + + LGK + F+Y +PSE + +D V + F++
Sbjct: 190 LI---ENIFTLQIQPFLGK-------EKPLFVYHFPSEQACLASINKKDS-RVSERFEIF 238
Query: 357 YRGVEISSGGQR-----EHRHDILVEQIREKGLN-PESF--EFYLRAFEYGMPPHGGFGL 408
++G+E+ +G E R + + + +N PE +++L A +G+P G +
Sbjct: 239 FKGIELGNGFHELTDYFEQRKRFIKDNRKRCDMNLPEQKIDDYFLDAIHHGLPTCSGVAI 298
Query: 409 GAERLIMRMLDIGNIREVILFPRDR 433
G +RLIM L+ +I +V+ F +R
Sbjct: 299 GLDRLIMIALNKNSIDQVMSFSFER 323
>gb|AAD12351.1| (U01814) unknown [Mycoplasma genitalium]
Length = 177
Score = 69.5 bits (167), Expect = 7e-11
Identities = 38/102 (37%), Positives = 55/102 (53%), Gaps = 2/102 (1%)
Query: 333 SEAKPFYIMKYEDKPE--VCKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPESFE 390
S+ K +I +E + + FDL G EI SG R + + + ++P F
Sbjct: 48 SKPKQEWIDNFESNKNEALSEQFDLVLNGFEIGSGSIRINDPIVQKRLMNSLNIDPNKFA 107
Query: 391 FYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRD 432
F L A++YG P HGG GLG +RL+M + NIREVI FP++
Sbjct: 108 FLLEAYQYGAPVHGGMGLGIDRLMMILNQTDNIREVIAFPKN 149
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.320 0.141 0.408
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 167256269
Number of Sequences: 2977
Number of extensions: 7505725
Number of successful extensions: 18700
Number of sequences better than 1.0e-10: 177
Number of HSP's better than 0.0 without gapping: 53
Number of HSP's successfully gapped in prelim test: 124
Number of HSP's that attempted gapping in prelim test: 18101
Number of HSP's gapped (non-prelim): 247
length of query: 438
length of database: 189,106,746
effective HSP length: 56
effective length of query: 382
effective length of database: 155,591,474
effective search space: 59435943068
effective search space used: 59435943068
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 166 (69.1 bits)