BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0657 (PAB0657) DE:HIT-LIKE PROTEIN
(147 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||D75073 hit-like protein PAB0657 - Pyrococcus abyssi (strain... 305 1e-82
pir||D71092 hypothetical protein PH1001 - Pyrococcus horikoshii ... 213 6e-55
pir||E75192 hit family protein (hit). PAB2301 - Pyrococcus abyss... 113 1e-24
pir||F71224 hypothetical protein PH0057 - Pyrococcus horikoshii ... 112 2e-24
gi|11499793 HIT family protein (hit) [Archaeoglobus fulgidus] >g... 103 9e-22
sp|Q58276|Y866_METJA HYPOTHETICAL HIT-LIKE PROTEIN MJ0866 >gi|28... 98 7e-20
gb|AAK40588.1| HIT-like protein, hypothetical (hit) [Sulfolobus... 97 1e-19
pir||G72766 probable hit-like protein APE0122 - Aeropyrum pernix... 96 2e-19
pir||B64408 histidine triad (HIT) protein MJ0866 - Methanococcus... 95 3e-19
pir||D70485 hypothetical protein aq_2159 - Aquifex aeolicus >gi|... 92 2e-18
gb|AAG17335.1|AF265558_2 (AF265558) unknown [Mycobacterium smegm... 90 1e-17
pir||D70571 hypothetical protein Rv2613c - Mycobacterium tubercu... 88 4e-17
emb|CAB09619.1| (Z96801) hypothetical protein MLCL581.17c [Mycob... 87 8e-17
gb|AAG20065.1| (AE005086) histidine triad protein; Hit2 [Halobac... 83 2e-15
gb|AAG20321.1| (AE005106) histidine triad protein; Hit1 [Halobac... 80 2e-14
gb|AAK42339.1| Histidine triad (Hit) family protein, putative [S... 80 2e-14
sp|P95937|YHIT_SULSO HYPOTHETICAL HIT-LIKE PROTEIN C01039 >gi|74... 80 2e-14
emb|CAC12267.1| (AL445066) histidine triad (HIT) related protein... 78 5e-14
pir||F83481 probable HIT family protein PA1306 [imported] - Pseu... 77 1e-13
emb|CAB70932.1| (AL137778) hypothetical HIT family protein SCL2.... 76 2e-13
dbj|BAB04908.1| (AP001511) Hit-like protein involved in cell-cyc... 74 1e-12
gi|6320511 member of the histidine triad family; Hnt2p [Saccharo... 73 2e-12
sp|P49776|APH1_SCHPO BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE (ASYMMET... 72 4e-12
pir||F81395 HIT-like protein Cj0499 [imported] - Campylobacter j... 71 5e-12
dbj|BAB06462.1| (AP001516) cell-cycle regulation histidine triad... 71 5e-12
sp|Q11066|YHIT_MYCTU HYPOTHETICAL HIT-LIKE PROTEIN RV1262C >gi|7... 70 1e-11
emb|CAB92785.1| (Z29068) putative HIT-like protein [Mycoplasma h... 70 1e-11
sp|P94252|YHIT_BORBU HYPOTHETICAL HIT-LIKE PROTEIN BB0379 >gi|17... 69 2e-11
pir||B70147 protein kinase C inhibitor homolog - Lyme disease sp... 69 2e-11
sp|P75504|YHIT_MYCPN HYPOTHETICAL 16.1 KDA PROTEIN HIT-LIKE PROT... 67 9e-11
pir||D71903 hit family protein - Helicobacter pylori (strain J99... 67 9e-11
>pir||D75073 hit-like protein PAB0657 - Pyrococcus abyssi (strain Orsay)
>gi|5458401|emb|CAB49889.1| (AJ248286) HIT-LIKE PROTEIN
[Pyrococcus abyssi]
Length = 147
Score = 305 bits (774), Expect = 1e-82
Identities = 147/147 (100%), Positives = 147/147 (100%)
Query: 1 MECPFCHPKPENVVYEDKFIRILLDNYPANPGHLLVVPKRHVTSIGNLTEDEKLALLKGI 60
MECPFCHPKPENVVYEDKFIRILLDNYPANPGHLLVVPKRHVTSIGNLTEDEKLALLKGI
Sbjct: 1 MECPFCHPKPENVVYEDKFIRILLDNYPANPGHLLVVPKRHVTSIGNLTEDEKLALLKGI 60
Query: 61 ELAVKALKRALKADGFNVGINIGKAAGQTVDHIHIHVIPRYEGDCDYPEGGIRKAVLNFP 120
ELAVKALKRALKADGFNVGINIGKAAGQTVDHIHIHVIPRYEGDCDYPEGGIRKAVLNFP
Sbjct: 61 ELAVKALKRALKADGFNVGINIGKAAGQTVDHIHIHVIPRYEGDCDYPEGGIRKAVLNFP 120
Query: 121 DENLRNTKNRLSSKEIERIRRVLNGSE 147
DENLRNTKNRLSSKEIERIRRVLNGSE
Sbjct: 121 DENLRNTKNRLSSKEIERIRRVLNGSE 147
>pir||D71092 hypothetical protein PH1001 - Pyrococcus horikoshii
>gi|3257415|dbj|BAA30098.1| (AP000004) 150aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 150
Score = 213 bits (538), Expect = 6e-55
Identities = 99/149 (66%), Positives = 123/149 (82%), Gaps = 4/149 (2%)
Query: 1 MECPFCHPKPENVVYEDKFIRILLDNYPANPGHLLVVPKRHVTSIGNLTEDEKLALLKGI 60
M+CPFC+P EN++YED IRILLDNYPANPGHLL+VP+RHVT + L+E EK +LL+GI
Sbjct: 1 MKCPFCNPIKENILYEDDTIRILLDNYPANPGHLLIVPRRHVTKLEELSEGEKASLLRGI 60
Query: 61 ELAVKALKRALKADGFNVGINIGKAAGQTVDHIHIHVIPRYEGDCDYPEGGIRKAVLNFP 120
E+A++ALK+ L DGFNVGINIGKAAGQTV+H+HIHVIPR+ DC YP+GGIRKAVL+
Sbjct: 61 EIAIEALKKTLNPDGFNVGINIGKAAGQTVEHLHIHVIPRFNNDCKYPKGGIRKAVLDVK 120
Query: 121 DENL----RNTKNRLSSKEIERIRRVLNG 145
DENL R TKNRL +++E +RR L+G
Sbjct: 121 DENLEDEERWTKNRLPREKVEELRRALHG 149
>pir||E75192 hit family protein (hit). PAB2301 - Pyrococcus abyssi (strain
Orsay) >gi|5457497|emb|CAB48988.1| (AJ248283) HIT FAMILY
PROTEIN (HIT). [Pyrococcus abyssi]
Length = 185
Score = 113 bits (280), Expect = 1e-24
Identities = 52/112 (46%), Positives = 76/112 (67%), Gaps = 7/112 (6%)
Query: 3 CPFCHPKPEN------VVYEDKFIRILLDNYPANPGHLLVVPKRHVTSIGNLTEDEKLAL 56
C FC EN ++Y K I+++NYP NPGH++V P RHV SI +LTE+E L +
Sbjct: 38 CIFCDFPKENRDRERLILYRGKHAFIIMNNYPYNPGHVMVAPYRHVASIEDLTEEEMLEI 97
Query: 57 LKGIELAVKALKRALKADGFNVGINIGKAAGQTVD-HIHIHVIPRYEGDCDY 107
+K L +KA+++ +K DGFN+G NIGK AG VD H+H+H++PR+ GD ++
Sbjct: 98 MKLAALIMKAIRKVMKPDGFNLGFNIGKVAGAGVDGHVHLHIVPRWNGDTNF 149
>pir||F71224 hypothetical protein PH0057 - Pyrococcus horikoshii
>gi|3256442|dbj|BAA29125.1| (AP000001) 168aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 168
Score = 112 bits (277), Expect = 2e-24
Identities = 51/112 (45%), Positives = 76/112 (67%), Gaps = 7/112 (6%)
Query: 3 CPFCHPKPEN------VVYEDKFIRILLDNYPANPGHLLVVPKRHVTSIGNLTEDEKLAL 56
C FC EN ++Y K I+++NYP NPGH++V P RHV SI +LT++E L +
Sbjct: 21 CIFCDFPKENRDKERLILYRGKHAFIIMNNYPYNPGHVMVAPYRHVASIEDLTDEEMLEI 80
Query: 57 LKGIELAVKALKRALKADGFNVGINIGKAAGQTVD-HIHIHVIPRYEGDCDY 107
+K L +KA+++ +K DGFN+G NIGK AG VD H+H+H++PR+ GD ++
Sbjct: 81 MKLAALIMKAIRKVMKPDGFNLGFNIGKVAGAGVDGHVHLHIVPRWNGDTNF 132
>gi|11499793 HIT family protein (hit) [Archaeoglobus fulgidus]
>gi|7434503|pir||C69526 histidine triad protein AF2211 -
Archaeoglobus fulgidus >gi|2648315|gb|AAB89043.1|
(AE000953) HIT family protein (hit) [Archaeoglobus
fulgidus]
Length = 160
Score = 103 bits (255), Expect = 9e-22
Identities = 47/113 (41%), Positives = 73/113 (64%), Gaps = 7/113 (6%)
Query: 2 ECPFCHPKPEN------VVYEDKFIRILLDNYPANPGHLLVVPKRHVTSIGNLTEDEKLA 55
EC FC EN ++Y K ++++ P NPGH++V P RH+ SI ++TE+E +
Sbjct: 20 ECVFCTAPKENRDRENLILYRGKTCYVIMNRNPYNPGHVMVNPYRHIPSIEDMTEEEIVE 79
Query: 56 LLKGIELAVKALKRALKADGFNVGINIGKAAGQTV-DHIHIHVIPRYEGDCDY 107
+K + L++KA++ + DGFNVG+NIGK AG + H+HIHV+PR+ GD +
Sbjct: 80 AMKLVRLSLKAIREVMNPDGFNVGVNIGKVAGAGIAAHLHIHVVPRWNGDTSF 132
>sp|Q58276|Y866_METJA HYPOTHETICAL HIT-LIKE PROTEIN MJ0866 >gi|2826341|gb|AAB98871.1|
(U67530) HIT family protein (hit) [Methanococcus
jannaschii]
Length = 129
Score = 97.5 bits (239), Expect = 7e-20
Identities = 51/118 (43%), Positives = 69/118 (58%), Gaps = 5/118 (4%)
Query: 3 CPFCH----PKPENVVYEDKFIRILLDNYPANPGHLLVVPKRHVTSIGNLTEDEKLALLK 58
C FC P VVYED+ + LD P N GH LVVPK+H + +DE +K
Sbjct: 2 CIFCKIINGEIPAKVVYEDEHVLAFLDINPRNKGHTLVVPKKHYERFDEMPDDELCNFIK 61
Query: 59 GIELAVKALKRALKADGFNVGINIGKAAGQTVDHIHIHVIPRYEGDCDYPEGGIRKAV 116
G++ V+ LK+ L DG+N+ N G+ AGQ V+H+H H+IPRYEGD + + G K V
Sbjct: 62 GVKKTVEVLKK-LGFDGYNIVNNNGRVAGQEVNHVHFHIIPRYEGDGEVVKFGEVKNV 118
>gb|AAK40588.1| HIT-like protein, hypothetical (hit) [Sulfolobus solfataricus]
Length = 171
Score = 96.7 bits (237), Expect = 1e-19
Identities = 53/147 (36%), Positives = 86/147 (58%), Gaps = 10/147 (6%)
Query: 2 ECPFCHP-KPEN-----VVYEDKFIRILLDNYPANPGHLLVVPKRHVTSIGNLTEDEKLA 55
EC FC K EN +VY K I+L+ +P N H++VVP RHV S+ L+ DE L
Sbjct: 23 ECLFCRVIKEENDEQNYIVYRGKHAFIILNAFPYNTAHVMVVPYRHVPSVELLSNDEALD 82
Query: 56 LLKGIELAVKALKRALKADGFNVGINIGKAAGQTVD-HIHIHVIPRYEGDCDYPEGGIRK 114
+ +A++A++ DGFN+G+NIG+ AG ++ HIH+H++PR+ GD ++
Sbjct: 83 IFTLSTIAIRAIRDIYAPDGFNIGVNIGRVAGAGIESHIHVHIVPRWNGDSNFMPVIFNT 142
Query: 115 AVLNFPDENLRNTKNRLSSKEIERIRR 141
V+ E L +T +L++K E +++
Sbjct: 143 KVM---PETLSDTFKKLNTKVNEIMKK 166
>pir||G72766 probable hit-like protein APE0122 - Aeropyrum pernix (strain K1)
>gi|5103512|dbj|BAA79033.1| (AP000058) 184aa long
hypothetical hit-like protein [Aeropyrum pernix]
Length = 184
Score = 96.0 bits (235), Expect = 2e-19
Identities = 42/96 (43%), Positives = 63/96 (64%), Gaps = 1/96 (1%)
Query: 13 VVYEDKFIRILLDNYPANPGHLLVVPKRHVTSIGNLTEDEKLALLKGIELAVKALKRALK 72
+VY ++L+ YP N GH++V P RHV + +LT DE + + K + +VKALKR
Sbjct: 55 IVYRGSLSYVILNKYPYNSGHIMVTPYRHVAELEDLTMDEIVEMAKLVRASVKALKRVYA 114
Query: 73 ADGFNVGINIGKAAGQTV-DHIHIHVIPRYEGDCDY 107
GFN+G+NIG+AAG + H HIH++PR+ GD ++
Sbjct: 115 PHGFNIGVNIGEAAGAGIAGHFHIHIVPRWRGDSNF 150
>pir||B64408 histidine triad (HIT) protein MJ0866 - Methanococcus jannaschii
Length = 129
Score = 95.2 bits (233), Expect = 3e-19
Identities = 50/118 (42%), Positives = 68/118 (57%), Gaps = 5/118 (4%)
Query: 3 CPFCH----PKPENVVYEDKFIRILLDNYPANPGHLLVVPKRHVTSIGNLTEDEKLALLK 58
C FC P VVYED+ + LD P N GH LVVPK+H + +DE +K
Sbjct: 2 CIFCKIINGEIPAKVVYEDEHVLAFLDINPRNKGHTLVVPKKHYERFDEMPDDELCNFIK 61
Query: 59 GIELAVKALKRALKADGFNVGINIGKAAGQTVDHIHIHVIPRYEGDCDYPEGGIRKAV 116
G++ V+ LK+ L DG+N+ N G+ AGQ V+H+H H+IPRY GD + + G K V
Sbjct: 62 GVKKTVEVLKK-LGFDGYNIVNNNGRVAGQEVNHVHFHIIPRYXGDGEVVKFGEVKNV 118
>pir||D70485 hypothetical protein aq_2159 - Aquifex aeolicus
>gi|2984367|gb|AAC07886.1| (AE000776) putative protein
[Aquifex aeolicus]
Length = 191
Score = 92.4 bits (226), Expect = 2e-18
Identities = 55/153 (35%), Positives = 89/153 (57%), Gaps = 16/153 (10%)
Query: 3 CPFCHP---KPEN-----VVYEDKFIRILLDNYPANPGHLLVVPKRHVTSIGNLTEDEKL 54
C CH PE +VY+ K I+L+ YP N GHL++VP +H+ + + E+ L
Sbjct: 45 CFLCHALSQPPEKWKEVLLVYKGKNAFIILNKYPYNTGHLMIVPVKHIGNYEEVDEETAL 104
Query: 55 ALLKGIELAVKALKRALKADGFNVGINIGKAAGQTV-DHIHIHVIPRYEGDCDYPEGGIR 113
+ K +++++KALK+ K GFNVG N G+ AG + +HIH+HV+PR+ GD ++ +
Sbjct: 105 EMHKLLQVSLKALKKEYKPHGFNVGYNFGRPAGAGLEEHIHLHVVPRWNGDTNFMPVLAQ 164
Query: 114 KAVLNFPDENLRNTKNRLSSKEIERIRRVLNGS 146
V++ E+L +T +R+ + I VLN S
Sbjct: 165 TKVIS---EDLYSTYDRVK----KAIEEVLNES 190
>gb|AAG17335.1|AF265558_2 (AF265558) unknown [Mycobacterium smegmatis]
Length = 205
Score = 89.7 bits (219), Expect = 1e-17
Identities = 40/96 (41%), Positives = 66/96 (68%), Gaps = 1/96 (1%)
Query: 13 VVYEDKFIRILLDNYPANPGHLLVVPKRHVTSIGNLTEDEKLALLKGIELAVKALKRALK 72
+V K + +L+ YP NPGHL+VVP R V+ + +LTEDE L+ + A++ +K +
Sbjct: 65 MVARGKRVYAVLNLYPYNPGHLMVVPYRRVSELEDLTEDESSELMAFTQKAIRVIKAVSR 124
Query: 73 ADGFNVGINIGKAAGQTV-DHIHIHVIPRYEGDCDY 107
GFNVG+N+G +AG ++ +H+H+HV+PR+ GD ++
Sbjct: 125 PHGFNVGLNLGSSAGGSLAEHLHMHVVPRWGGDANF 160
>pir||D70571 hypothetical protein Rv2613c - Mycobacterium tuberculosis (strain
H37RV) >gi|2104300|emb|CAB08629.1| (Z95387) hypothetical
protein Rv2613c [Mycobacterium tuberculosis]
Length = 195
Score = 88.2 bits (215), Expect = 4e-17
Identities = 39/96 (40%), Positives = 65/96 (67%), Gaps = 1/96 (1%)
Query: 13 VVYEDKFIRILLDNYPANPGHLLVVPKRHVTSIGNLTEDEKLALLKGIELAVKALKRALK 72
VV K + +L+ YP NPGHL+VVP R V+ + +LT+ E L+ + A++ +K +
Sbjct: 71 VVARGKLVYAVLNLYPYNPGHLMVVPYRRVSELEDLTDLESAELMAFTQKAIRVIKNVSR 130
Query: 73 ADGFNVGINIGKAAGQTV-DHIHIHVIPRYEGDCDY 107
GFNVG+N+G +AG ++ +H+H+HV+PR+ GD ++
Sbjct: 131 PHGFNVGLNLGTSAGGSLAEHLHVHVVPRWGGDANF 166
>emb|CAB09619.1| (Z96801) hypothetical protein MLCL581.17c [Mycobacterium leprae]
Length = 186
Score = 87.4 bits (213), Expect = 8e-17
Identities = 38/96 (39%), Positives = 65/96 (67%), Gaps = 1/96 (1%)
Query: 13 VVYEDKFIRILLDNYPANPGHLLVVPKRHVTSIGNLTEDEKLALLKGIELAVKALKRALK 72
VV + + +L+ YP NPGHL+VVP R V+ + +LT+ E L+ + A++ +K +
Sbjct: 50 VVARGELVYAVLNLYPYNPGHLMVVPYRQVSELEDLTDAESAELMTFTQKAIRVIKNVSR 109
Query: 73 ADGFNVGINIGKAAGQTV-DHIHIHVIPRYEGDCDY 107
GFNVG+N+G +AG ++ +H+H+HV+PR+ GD ++
Sbjct: 110 PHGFNVGLNLGTSAGGSLAEHLHVHVVPRWGGDANF 145
>gb|AAG20065.1| (AE005086) histidine triad protein; Hit2 [Halobacterium sp. NRC-1]
Length = 181
Score = 82.7 bits (201), Expect = 2e-15
Identities = 42/115 (36%), Positives = 61/115 (52%), Gaps = 8/115 (6%)
Query: 1 MECPFC------HPKPENVVYEDKFIRILLDNYPANPGHLLVVPKRHVTSIGNLTEDEKL 54
++C FC H + VV ++L+NYP NPGH +V+P H G+L D L
Sbjct: 23 VDCVFCAFPGREHARQHLVVARTDHAAVMLNNYPYNPGHCMVIPDVHTGDYGDLDADTLL 82
Query: 55 ALLKGIELAVKALKRALKADGFNVGINI--GKAAGQTVDHIHIHVIPRYEGDCDY 107
+ + + AL AL D FN G+N+ G A G DH+H HV+PR+ GD ++
Sbjct: 83 DHARLKQATLDALDAALGPDAFNTGLNLGGGAAGGSIGDHLHTHVVPRWNGDTNF 137
>gb|AAG20321.1| (AE005106) histidine triad protein; Hit1 [Halobacterium sp. NRC-1]
Length = 142
Score = 79.6 bits (193), Expect = 2e-14
Identities = 39/107 (36%), Positives = 56/107 (51%), Gaps = 4/107 (3%)
Query: 2 ECPFCH----PKPENVVYEDKFIRILLDNYPANPGHLLVVPKRHVTSIGNLTEDEKLALL 57
+C FC P VV+ED LD P PGH LV+PK H ++ + D+ A+
Sbjct: 4 DCVFCQIIADEIPARVVHEDADTLAFLDATPMAPGHTLVIPKTHAATLADTPGDDATAVF 63
Query: 58 KGIELAVKALKRALKADGFNVGINIGKAAGQTVDHIHIHVIPRYEGD 104
+ + ++ A+ AD +G N G AAGQ V H+H H+IPR+ D
Sbjct: 64 ETLHALAPTVEAAVDADATTIGFNNGTAAGQEVPHVHGHIIPRFADD 110
>gb|AAK42339.1| Histidine triad (Hit) family protein, putative [Sulfolobus
solfataricus]
Length = 139
Score = 79.6 bits (193), Expect = 2e-14
Identities = 38/94 (40%), Positives = 54/94 (57%)
Query: 13 VVYEDKFIRILLDNYPANPGHLLVVPKRHVTSIGNLTEDEKLALLKGIELAVKALKRALK 72
+VY + + LD +P PGH LVVP+ H + ++ED L + A+K+ALK
Sbjct: 16 IVYSNDRVVAFLDKFPITPGHTLVVPRTHYENFLEISEDVIPYLCTAVRKISIAVKKALK 75
Query: 73 ADGFNVGINIGKAAGQTVDHIHIHVIPRYEGDCD 106
ADG + NIGK+AGQ V H H H++P + D D
Sbjct: 76 ADGIRILTNIGKSAGQVVFHSHFHIVPTWSQDPD 109
>sp|P95937|YHIT_SULSO HYPOTHETICAL HIT-LIKE PROTEIN C01039 >gi|7434514|pir||S74070
histidine triad (HIT) protein c0139 - Sulfolobus
solfataricus >gi|1707769|emb|CAA69441.1| (Y08256) HIT
protein [Sulfolobus solfataricus]
Length = 139
Score = 79.6 bits (193), Expect = 2e-14
Identities = 38/94 (40%), Positives = 54/94 (57%)
Query: 13 VVYEDKFIRILLDNYPANPGHLLVVPKRHVTSIGNLTEDEKLALLKGIELAVKALKRALK 72
+VY + + LD +P PGH LVVP+ H + ++ED L + A+K+ALK
Sbjct: 16 IVYSNDRVVAFLDKFPITPGHTLVVPRTHYENFLEISEDVIPYLCTAVRKISIAVKKALK 75
Query: 73 ADGFNVGINIGKAAGQTVDHIHIHVIPRYEGDCD 106
ADG + NIGK+AGQ V H H H++P + D D
Sbjct: 76 ADGIRILTNIGKSAGQVVFHSHFHIVPTWSQDPD 109
>emb|CAC12267.1| (AL445066) histidine triad (HIT) related protein [Thermoplasma
acidophilum]
Length = 147
Score = 78.0 bits (189), Expect = 5e-14
Identities = 44/134 (32%), Positives = 70/134 (51%), Gaps = 10/134 (7%)
Query: 3 CPFCHP----KPENVVYEDKFIRILLDNYPANPGHLLVVPKRHVTSIGNLTEDEKLALLK 58
C FC+ + +V E+ + +DN P PGH+LV+PK H +I ++ + +
Sbjct: 7 CVFCNEIITKRNAAIVAENDMVISFMDNAPVEPGHILVIPKEHFENIFDIDSRYYIEVQL 66
Query: 59 GIELAVKALKRALKADGFNVGINIGKAAGQTVDHIHIHVIPRYEGDCDYPEGGIRKAVLN 118
+ KA+ +A+ ADG N+G N G A Q V H H+HVIPR+ CD P + LN
Sbjct: 67 MAKRVAKAVMKAMGADGINIGQNNGWCANQRVMHFHVHVIPRW---CDKP---FKWGRLN 120
Query: 119 FPDENLRNTKNRLS 132
++L T +++
Sbjct: 121 VSFDDLSETARKIA 134
>pir||F83481 probable HIT family protein PA1306 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9947243|gb|AAG04695.1|AE004560_3 (AE004560) probable
HIT family protein [Pseudomonas aeruginosa]
Length = 153
Score = 76.9 bits (186), Expect = 1e-13
Identities = 41/109 (37%), Positives = 64/109 (58%), Gaps = 5/109 (4%)
Query: 1 MECPFCH----PKPENVVYEDKFIRILLDNYPANPGHLLVVPKRHVTSIGNLTEDEKLAL 56
M+C FC +P + ++ED+ +LLD +P P H+L+V + H + +L+ + AL
Sbjct: 6 MDCVFCAIAGGREPAHRLFEDEHFIVLLDIFPLRPAHVLIVAREHALHLSDLSAAARDAL 65
Query: 57 LKGIELAVKALKRA-LKADGFNVGINIGKAAGQTVDHIHIHVIPRYEGD 104
L E +AL+RA +G N+ +N G AA Q V H+H+H+IPR GD
Sbjct: 66 LALAERIGRALRRAGFGVEGINLLLNDGVAANQHVAHLHLHLIPRRRGD 114
>emb|CAB70932.1| (AL137778) hypothetical HIT family protein SCL2.20c [Streptomyces
coelicolor A3(2)]
Length = 186
Score = 76.1 bits (184), Expect = 2e-13
Identities = 41/111 (36%), Positives = 62/111 (54%), Gaps = 6/111 (5%)
Query: 3 CPFCHPKPEN-----VVYEDKFIRILLDNYPANPGHLLVVPKRHVTSIGNLTEDEKLALL 57
CPFC ++ +V + + +L+ YP N GHL++VP RHV L E L
Sbjct: 44 CPFCSIPAKSDEDGLIVRRGEHVYAVLNLYPYNGGHLMIVPYRHVADYTELNAVETAELA 103
Query: 58 KGIELAVKALKRALKADGFNVGINIGKAAGQTV-DHIHIHVIPRYEGDCDY 107
+ + A+ AL+ A A GFN+G+N G AG + H+H HV+PR+ GD ++
Sbjct: 104 ELTKQAMTALRAASGAQGFNLGMNQGAVAGAGIAAHLHQHVVPRWGGDTNF 154
>dbj|BAB04908.1| (AP001511) Hit-like protein involved in cell-cycle regulation
[Bacillus halodurans]
Length = 142
Score = 73.7 bits (178), Expect = 1e-12
Identities = 41/107 (38%), Positives = 57/107 (52%), Gaps = 5/107 (4%)
Query: 3 CPFCH----PKPENVVYEDKFIRILLDNYPANPGHLLVVPKRHVTSIGNLTEDEKLALLK 58
C FC P VYED + LD GH LV+PK H ++ L+E+ +L
Sbjct: 7 CIFCKIIAGEIPSATVYEDDHVYAFLDISQVTKGHTLVIPKVHKRNVFELSEEIASSLFA 66
Query: 59 GIELAVKALKRALKADGFNVGINIGKAAGQTVDHIHIHVIPRY-EGD 104
+ +A+ A + G N+ N G+AAGQTV H H+H++PRY EGD
Sbjct: 67 AVPKISRAINDAFQPIGMNIVNNNGEAAGQTVFHYHLHLLPRYGEGD 113
>gi|6320511 member of the histidine triad family; Hnt2p [Saccharomyces
cerevisiae] >gi|1723425|sp|P49775|HNT2_YEAST HIT FAMILY
PROTEIN 2 >gi|2131421|pir||S61191 asymmetrical hydrolase
homolog YDR305c - yeast (Saccharomyces cerevisiae)
>gi|849222|gb|AAB64741.1| (U28374) Hnt2p: yeast homolog
of histidine triad nucleotide-binding protein (HINT)
[Saccharomyces cerevisiae]
Length = 217
Score = 73.0 bits (176), Expect = 2e-12
Identities = 38/93 (40%), Positives = 55/93 (58%), Gaps = 1/93 (1%)
Query: 11 ENVVYEDKFIRILLDNYPANPGHLLVVPKRH-VTSIGNLTEDEKLALLKGIELAVKALKR 69
E V Y+ K+ L++ P PGH+L+VP R V ++ +LT E K ++L + +K
Sbjct: 25 EQVFYKSKYTYALVNLKPIVPGHVLIVPLRTTVLNLSDLTMPESQDYFKTLQLIHRFIKW 84
Query: 70 ALKADGFNVGINIGKAAGQTVDHIHIHVIPRYE 102
KAD NV I G AGQ+V H+H H+IPRY+
Sbjct: 85 QYKADSINVAIQDGPEAGQSVPHLHTHIIPRYK 117
>sp|P49776|APH1_SCHPO BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE (ASYMMETRICAL) (DIADENOSINE
5',5'''-P1,P4-TETRAPHOSPHATE ASYMMETRICAL HYDROLASE)
(DIADENOSINE TETRAPHOSPHATASE) (AP4A HYDROLASE)
(AP4AASE) >gi|2130186|pir||S64700
bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) (EC
3.6.1.17) - fission yeast (Schizosaccharomyces pombe)
>gi|7490436|pir||T41374 diadenosine tetraphosphatase -
fission yeast (Schizosaccharomyces pombe)
>gi|965075|gb|AAC49143.1| (U32615) diadenosine
5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase
[Schizosaccharomyces pombe] >gi|2213545|emb|CAB09779.1|
(Z97052) diadenosine tetraphosphatase
[Schizosaccharomyces pombe]
Length = 182
Score = 71.8 bits (173), Expect = 4e-12
Identities = 34/97 (35%), Positives = 51/97 (52%)
Query: 8 PKPENVVYEDKFIRILLDNYPANPGHLLVVPKRHVTSIGNLTEDEKLALLKGIELAVKAL 67
P V Y K ++ P PGH+LV+P+R V + +LT E L + + +
Sbjct: 11 PVGSQVFYRTKLSAAFVNLKPILPGHVLVIPQRAVPRLKDLTPSELTDLFTSVRKVQQVI 70
Query: 68 KRALKADGFNVGINIGKAAGQTVDHIHIHVIPRYEGD 104
++ A N+GI G AGQTV H+H+H+IPR + D
Sbjct: 71 EKVFSASASNIGIQDGVDAGQTVPHVHVHIIPRKKAD 107
>pir||F81395 HIT-like protein Cj0499 [imported] - Campylobacter jejuni (strain
NCTC 11168) >gi|6967970|emb|CAB75137.1| (AL139075)
HIT-like protein [Campylobacter jejuni]
Length = 161
Score = 71.4 bits (172), Expect = 5e-12
Identities = 36/113 (31%), Positives = 61/113 (53%), Gaps = 8/113 (7%)
Query: 3 CPFCH-------PKPENVVYEDKFIRILLDNYPANPGHLLVVPKRHVTSIGNLTEDEKLA 55
CPFC + V++ K +++ YP + GH +V+P H I NL+++
Sbjct: 20 CPFCDCANKIKSDEELGVIFRAKHCFGVMNRYPYSAGHFMVIPYIHEEHIENLSDEIWQE 79
Query: 56 LLKGIELAVKALKRALKADGFNVGINIGKAAGQTVD-HIHIHVIPRYEGDCDY 107
+ + L VK LK + A+G N+G+N+ K AG + H H H++PR+ GD ++
Sbjct: 80 MSYFVRLGVKILKEQIHANGVNIGMNLSKDAGAGIAFHCHYHLVPRWSGDTNF 132
>dbj|BAB06462.1| (AP001516) cell-cycle regulation histidine triad (Hit family)
[Bacillus halodurans]
Length = 169
Score = 71.4 bits (172), Expect = 5e-12
Identities = 36/92 (39%), Positives = 55/92 (59%), Gaps = 2/92 (2%)
Query: 9 KPENVVYEDKFIRILLDNYPANPGHLLVVPKRHVTSIGNLTEDEKLALLKGIELAVKALK 68
+P +VVYED+ + +LD+ P + GH L+ PK HV I ++ + A++KG+ + VKA+K
Sbjct: 38 RPVHVVYEDQLVCGILDHDPFHEGHTLLFPKAHVIEIEDVNQKTANAIMKGVTIVVKAIK 97
Query: 69 RALKADGFNVGINIGKAAGQTVDHIHIHVIPR 100
G + N G+ +DH HIHVIPR
Sbjct: 98 ALYNPAGITICQNGGEF--NDLDHYHIHVIPR 127
>sp|Q11066|YHIT_MYCTU HYPOTHETICAL HIT-LIKE PROTEIN RV1262C >gi|7434515|pir||F70753
hypothetical protein Rv1262c - Mycobacterium
tuberculosis (strain H37RV) >gi|3261595|emb|CAB00913.1|
(Z77137) hypothetical protein Rv1262c [Mycobacterium
tuberculosis]
Length = 144
Score = 69.9 bits (168), Expect = 1e-11
Identities = 44/109 (40%), Positives = 57/109 (51%), Gaps = 6/109 (5%)
Query: 1 MECPFCH----PKPENVVYEDKFIRILLDNYPANPGHLLVVPKRHVTSIGNLTEDEKLAL 56
M C FC P +YED +LD P GH LV+PKRH + + T E LA
Sbjct: 1 MPCVFCAIIAGEAPAIRIYEDGGYLAILDIRPFTRGHTLVLPKRHTVDLTD-TPPEALAD 59
Query: 57 LKGIELAVKALKRALK-ADGFNVGINIGKAAGQTVDHIHIHVIPRYEGD 104
+ I + RA K AD ++ IN G+AA QTV H+H+HV+P GD
Sbjct: 60 MVAIGQRIARAARATKLADATHIAINDGRAAFQTVFHVHLHVLPPRNGD 108
>emb|CAB92785.1| (Z29068) putative HIT-like protein [Mycoplasma hominis]
Length = 106
Score = 69.9 bits (168), Expect = 1e-11
Identities = 40/94 (42%), Positives = 58/94 (61%), Gaps = 4/94 (4%)
Query: 10 PENVVYEDKFIRILLDNYPANPGHLLVVPKRHVTSIGNLTEDEKLA--LLKGIELAVKAL 67
P ++YED+ D P + GH LV K H T++ ++ +D+ L+ +LK ELA+K +
Sbjct: 15 PAKIIYEDEKFIAFEDIKPVDKGHFLVTVKNHATNLYDI-DDQTLSSLILKSRELALKRV 73
Query: 68 KRALKADGFNVGINIGKAAGQTVDHIHIHVIPRY 101
K L A GFN+ IN +A QTV IH+H+IPRY
Sbjct: 74 KE-LGATGFNLIINNNLSADQTVFRIHVHIIPRY 106
>sp|P94252|YHIT_BORBU HYPOTHETICAL HIT-LIKE PROTEIN BB0379
>gi|1753229|gb|AAC44716.1|AAC44716 (U49938) protein
kinase C1 inhibitor Pkci [Borrelia burgdorferi]
Length = 139
Score = 69.5 bits (167), Expect = 2e-11
Identities = 41/109 (37%), Positives = 54/109 (48%), Gaps = 6/109 (5%)
Query: 2 ECPFCH----PKPENVVYEDKFIRILLDNYPANPGHLLVVPKRHVTSIGNLTEDEKLALL 57
+C FC P VYED + LD P GH LV+PK H S+ N+ + +L
Sbjct: 3 DCIFCKIINKELPSYKVYEDDLVLAFLDINPLTVGHTLVIPKEHSESLLNMDDKFNERVL 62
Query: 58 KGIELAVKALKRALKA--DGFNVGINIGKAAGQTVDHIHIHVIPRYEGD 104
K + ALKR + G N+ +G AGQ V H H HVIPR++ D
Sbjct: 63 KVCKKISNALKRINSSIYGGINIYSALGAGAGQEVFHTHFHVIPRFKND 111
>pir||B70147 protein kinase C inhibitor homolog - Lyme disease spirochete
>gi|2688285|gb|AAC66761.1| (AE001143) protein kinase C1
inhibitor (pkcI) [Borrelia burgdorferi]
Length = 149
Score = 69.5 bits (167), Expect = 2e-11
Identities = 41/109 (37%), Positives = 54/109 (48%), Gaps = 6/109 (5%)
Query: 2 ECPFCH----PKPENVVYEDKFIRILLDNYPANPGHLLVVPKRHVTSIGNLTEDEKLALL 57
+C FC P VYED + LD P GH LV+PK H S+ N+ + +L
Sbjct: 13 DCIFCKIINKELPSYKVYEDDLVLAFLDINPLTVGHTLVIPKEHSESLLNMDDKFNERVL 72
Query: 58 KGIELAVKALKRALKA--DGFNVGINIGKAAGQTVDHIHIHVIPRYEGD 104
K + ALKR + G N+ +G AGQ V H H HVIPR++ D
Sbjct: 73 KVCKKISNALKRINSSIYGGINIYSALGAGAGQEVFHTHFHVIPRFKND 121
>sp|P75504|YHIT_MYCPN HYPOTHETICAL 16.1 KDA PROTEIN HIT-LIKE PROTEIN (A65_ORF144)
>gi|2146255|pir||S73888 histidine triad protein
A65_orf144 - Mycoplasma pneumoniae (strain ATCC 29342)
>gi|1674261|gb|AAB96210.1| (AE000055) nucleotidyl
hydrolases/transferase [Mycoplasma pneumoniae]
Length = 144
Score = 67.1 bits (161), Expect = 9e-11
Identities = 41/106 (38%), Positives = 60/106 (55%), Gaps = 8/106 (7%)
Query: 3 CPFCHPKPENV----VYEDKFIRILLDNYPANPGHLLVVPKRHVTSIGNLTEDEKLALLK 58
C FC NV V E++ LD +P GH LV+PK+H + + T+DE L +
Sbjct: 12 CIFCGIVEGNVKSFKVGENEHAFAFLDAFPVADGHTLVIPKKHAVNYSS-TDDESLKAVS 70
Query: 59 GI--ELAVKALKRALKADGFNVGINIGKAAGQTVDHIHIHVIPRYE 102
+ E+A+K L++ L+ G N +N G AGQ V H H+HV+P+YE
Sbjct: 71 LLAKEMALK-LQQRLQPAGLNYVVNEGAKAGQEVFHYHMHVVPKYE 115
>pir||D71903 hit family protein - Helicobacter pylori (strain J99)
>gi|4155223|gb|AAD06245.1| (AE001499) HIT FAMILY PROTEIN
[Helicobacter pylori J99]
Length = 161
Score = 67.1 bits (161), Expect = 9e-11
Identities = 38/113 (33%), Positives = 66/113 (57%), Gaps = 9/113 (7%)
Query: 3 CPFC----HPKPEN---VVYEDKFIRILLDNYPANPGHLLVVPKRHVTSIGNLTEDEKLA 55
C FC +P ++ V+Y + + ++++ YP NPGHLL+VP H S+ L + L
Sbjct: 20 CVFCGISQNPTKDSENRVLYRNSDLFVVMNAYPYNPGHLLIVPHAHQASVELLDLNTWLN 79
Query: 56 LLKGIELAVKALKRALKADGFNVGINIGKAAGQTV-DHIHIHVIPRYEGDCDY 107
+ +KAL A A G N+G+N+ + AG + +H+H+H++PR+ GD ++
Sbjct: 80 MNALAPKILKAL-YAYGAQGINLGLNLHRNAGAGIPEHLHMHLVPRFLGDSNF 131
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.319 0.141 0.417
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 57363498
Number of Sequences: 2977
Number of extensions: 2310033
Number of successful extensions: 5296
Number of sequences better than 1.0e-10: 31
Number of HSP's better than 0.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 5256
Number of HSP's gapped (non-prelim): 31
length of query: 147
length of database: 189,106,746
effective HSP length: 51
effective length of query: 96
effective length of database: 158,583,909
effective search space: 15224055264
effective search space used: 15224055264
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 161 (67.1 bits)