BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB0739 (adkE) DE:adenylate kinase (adk) (EC 2.7.4.3) (220 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value sp|Q9UZN1|KAD_PYRAB ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 455 e-127 sp|O58844|KAD_PYRHO ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 430 e-120 gi|11498284 adenylate kinase (adk) [Archaeoglobus fulgidus] >gi|... 205 4e-52 sp|P16304|KAD_BACSU ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 195 4e-49 sp|P27142|KAD_BACST ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 194 1e-48 pir||T44404 adenylate kinase (EC 2.7.4.3) [imported] - Bacillus ... 182 2e-45 sp|P27143|KAD_LACLA ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 179 2e-44 sp|P43414|KAD_STRCO ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 175 3e-43 gb|AAG19963.1| (AE005078) adenylate kinase; Adk [Halobacterium s... 171 5e-42 pir||JC5039 adenylate kinase (EC 2.7.4.3) - Halobacterium salinarum 171 8e-42 pir||G83184 adenylate kinase PA3686 [imported] - Pseudomonas aer... 166 2e-40 pir||S50007 adenylate kinase (EC 2.7.4.3) - Streptomyces coelicolor 166 2e-40 sp|P33075|KAD1_SCHPO ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLAS... 164 6e-40 emb|CAA12055.1| (AJ224658) adenylate kinase [Neocallimastix fron... 162 2e-39 pir||PC4230 adenylate kinase (EC 2.7.4.3) - Streptomyces lividan... 162 2e-39 sp|P49974|KAD_STRLI ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 162 2e-39 sp|O66490|KAD_AQUAE ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 162 3e-39 sp|Q9Z409|KAD_PSEPU ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 160 2e-38 sp|Q9X1I8|KAD_THEMA ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 159 3e-38 emb|CAA12057.1| (AJ224660) adenylate kinase [Piromyces sp. E2] 158 6e-38 sp|P10772|KAD_PARDE ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 157 8e-38 sp|P24323|KAD_HAEIN ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 157 1e-37 pir||S15290 adenylate kinase (EC 2.7.4.3) - Haemophilus influenz... 157 1e-37 sp|P39068|KAD_BORPE ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 156 2e-37 gb|AAC41489.1| (L47154) adenylate kinase [Neisseria meningitidis... 155 3e-37 gb|AAC41506.1| (L47143) adenylate kinase [Neisseria meningitidis... 155 5e-37 pir||F81154 adenylate kinase NMB0823 [imported] - Neisseria meni... 155 5e-37 sp|P49980|KAD_NEIMA ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 154 9e-37 sp|P49979|KAD_NEIGO ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 153 1e-36 gb|AAC41492.1| (L47158) adenylate kinase [Neisseria meningitidis... 153 2e-36 emb|CAA12056.1| (AJ224659) adenylate kinase [Neocallimastix fron... 152 3e-36 emb|CAA68471.1| (Y00413) adenylate cyclase (AA 1 - 222) [Sacchar... 152 5e-36 sp|P49981|KAD_NEIMU ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 152 5e-36 sp|Q08480|KADB_ORYSA ADENYLATE KINASE B (ATP-AMP TRANSPHOSPHORYL... 151 6e-36 gb|AAC41510.1| (L47145) adenylate kinase [Neisseria meningitidis] 151 8e-36 gi|6320432 adenylate kinase; Adk1p [Saccharomyces cerevisiae] >g... 150 1e-35 pdb|1AKY| Atp:amp Phosphotransferase, Myokinase Mol_id: 1; Mol... 150 1e-35 pdb|3AKY| Atp:amp Phosphotransferase, Myokinase Mol_id: 1; Mol... 150 1e-35 sp|O69172|KAD_YERPE ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 150 1e-35 pir||KIPC adenylate kinase (EC 2.7.4.3) - Paracoccus denitrificans 149 3e-35 gb|AAD45371.1|AF163320_1 (AF163320) type 2 adenylate kinase [Cry... 149 3e-35 sp|P05082|KAD_ECOLI ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 147 9e-35 sp|P37407|KAD_SALTY ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 147 9e-35 gb|AAB40228.1| (U82664) adenylate kinase [Escherichia coli] 147 9e-35 emb|CAC18138.1| (AL451012) probable adenylate kinase [Neurospora... 147 1e-34 pir||C82255 adenylate kinase VC0986 [imported] - Vibrio cholerae... 146 3e-34 dbj|BAB09456.1| (AB012248) adenylate kinase [Arabidopsis thaliana] 145 3e-34 sp|O83604|KAD_TREPA ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 145 4e-34 gi|6321018 Adenylate kinase (mitochondrial GTP:AMP phosphotransf... 145 6e-34 sp|P33107|KAD_MICLU ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 144 8e-34 sp|P34346|KADX_CAEEL PROBABLE ADENYLATE KINASE ISOENZYME C29E4.8... 144 8e-34 sp|P08760|KAD3_BOVIN GTP:AMP PHOSPHOTRANSFERASE MITOCHONDRIAL (A... 144 1e-33 pdb|2AK3|A Chain A, Adenylate Kinase Isoenzyme-3 (Gtp: Amp Phosp... 144 1e-33 pdb|1DVR|A Chain A, Nucleoside Monophosphate Kinase, Myokinase M... 144 1e-33 sp|O51378|KAD_BORBU ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 144 1e-33 pdb|1E4V|A Chain A, Mutant G10v Of Adenylate Kinase From E. Coli... 144 1e-33 gi|4502013 adenylate kinase 2 isoform a; Adenylate kinase-2, mit... 143 1e-33 gi|7524346 adenylate kinase 2 isoform a; Adenylate kinase-2, mit... 143 1e-33 sp|Q08479|KADA_ORYSA ADENYLATE KINASE A (ATP-AMP TRANSPHOSPHORYL... 143 2e-33 sp|O82514|KAD_ARATH ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 142 3e-33 sp|P43412|KAD_YEREN ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 142 4e-33 dbj|BAB08805.1| (AB007649) adenylate kinase [Arabidopsis thaliana] 142 4e-33 sp|P57556|KAD_BUCAI ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 141 5e-33 sp|P29410|KAD2_RAT ADENYLATE KINASE ISOENZYME 2, MITOCHONDRIAL (... 141 9e-33 sp|Q9WTP7|KAD3_MOUSE GTP:AMP PHOSPHOTRANSFERASE MITOCHONDRIAL (A... 140 2e-32 pdb|1E4Y|A Chain A, Mutant P9l Of Adenylate Kinase From E. Coli,... 140 2e-32 pir||B29792 adenylate kinase (EC 2.7.4.3) 2B, mitochondrial - bo... 139 3e-32 sp|P08166|KAD2_BOVIN ADENYLATE KINASE ISOENZYME 2, MITOCHONDRIAL... 139 3e-32 pdb|1AK2| Adenylate Kinase Isoenzyme-2 >gi|1633467|pdb|2AK2| ... 139 3e-32 dbj|BAA91753.1| (AK001553) unnamed protein product [Homo sapiens... 139 3e-32 gi|8392883 adenylate kinase 2 [Mus musculus] >gi|6707706|sp|Q9WT... 138 4e-32 gb|AAF97187.1|AF268611_10 (AF268611) adenylate kinase [unculture... 137 1e-31 gi|7705272 adenylate kinase 3 alpha like [Homo sapiens] >gi|1113... 137 1e-31 gb|AAF54578.1| (AE003689) CG6612 gene product [Drosophila melano... 137 1e-31 gb|AAF47139.1| (AE003462) Adk2 gene product [Drosophila melanoga... 136 2e-31 sp|Q9PQP0|KAD_UREPA ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 136 2e-31 sp|P10251|KAD_MYCCA ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 136 3e-31 gi|6753022 adenylate kinase 4 [Mus musculus] >gi|6707708|sp|Q9WU... 134 7e-31 gi|8392885 adenylate kinase 4 [Rattus norvegicus] >gi|6707705|sp... 134 9e-31 gi|6978479 adenylate kinase 3 [Rattus norvegicus] >gi|266402|sp|... 134 1e-30 sp|Q9ZCS6|KAD_RICPR ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 133 1e-30 pir||B82825 adenylate kinase XF0275 [imported] - Xylella fastidi... 133 2e-30 gi|8051579 adenylate kinase 3; Adenylate kinase-3, mitochondrial... 132 3e-30 gi|11421812 adenylate kinase 3 [Homo sapiens] 132 3e-30 dbj|BAA77363.1| (AB020239) adenylate kinase 3 [Mus musculus] 132 3e-30 sp|Q59591|KAD_NEIAN ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 132 4e-30 sp|Q59596|KAD_NEIFL ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 131 1e-29 sp|Q59615|KAD_NEILA ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 131 1e-29 emb|CAB82091.1| (AL161803) adenylate kinase (fragment) [Streptom... 131 1e-29 dbj|BAA94761.1| (AB041773) adenylate kinase [Oryza sativa] 129 2e-29 sp|Q59594|KAD_NEICI ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 128 6e-29 sp|P49983|KADH_TRIVA ADENYLATE KINASE PRECURSOR (ATP-AMP TRANSPH... 127 8e-29 sp|Q9Z8U0|KAD_CHLPN ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 127 8e-29 sp|Q59627|KAD_NEIPO ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 127 1e-28 sp|Q9XD15|KAD_LEPIN ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) 127 1e-28 sp|P43188|KADC_MAIZE ADENYLATE KINASE, CHLOROPLAST (ATP-AMP TRAN... 126 2e-28 pir||T02575 adenylate kinase homolog T16B24.9 - Arabidopsis thal... 123 1e-27 dbj|BAB11331.1| (AB016886) contains similarity to adenylate kina... 123 2e-27 gb|AAD40604.1|AF115283_23 (AF115283) adenylate kinase [Leptospir... 122 4e-27 sp|Q09629|KADY_CAEEL PROBABLE ADENYLATE KINASE ISOENZYME ZK673.2... 122 5e-27 gi|10954728 adk gene homolog [Agrobacterium rhizogenes] >gi|8918... 121 6e-27 sp|P47417|KAD_MYCGE ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 120 1e-26 sp|O84130|KAD_CHLTR ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 120 2e-26 sp|Q9PKR0|KAD_CHLMU ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 119 3e-26 sp|O52352|KAD_MYCGA ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 118 4e-26 sp|O53796|KAD_MYCTU ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 115 5e-25 gb|AAC46846.1| (U19901) adenylate kinase [Giardia intestinalis] 114 8e-25 sp|P49982|KAD_GIALA ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 114 8e-25 gb|AAD39831.2| (AF156853) adenylate kinase [Leishmania donovani] 114 8e-25 sp|Q50299|KAD_MYCPN ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 113 1e-24 gb|AAC98046.1| (AC005896) putative adenylate kinase [Arabidopsis... 111 5e-24 sp|O33007|KAD_MYCLE ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 108 5e-23 gi|11429144 adenylate kinase 3 alpha like [Homo sapiens] 105 4e-22 gb|AAC47014.1| (U34075) nucleoside monophosphate kinase [Babesia... 104 9e-22 sp|O24706|KAD_SYNP6 ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 103 2e-21 emb|CAB89615.1| (AL354533) possible adenylate kinase [Leishmania... 102 4e-21 dbj|BAA85412.1| (AP000615) ESTs AU065232(E60855),C23624(S1554), ... 102 4e-21 gb|AAB59119.1| (M31102) adk gene product [Bacillus subtilis] 100 2e-20 sp|Q9RSK7|KAD_DEIRA ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 99 4e-20 pir||T21947 hypothetical protein F38B2.4 - Caenorhabditis elegan... 95 6e-19 sp|P73302|KAD_SYNY3 ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) 94 1e-18 emb|CAA35713.1| (X51329) Adk N-terminal (99 AA) [Bacillus subtilis] 91 1e-17 gb|AAG09688.1|AF183419_1 (AF183419) GTP:AMP phosphotransferase [... 90 3e-17 pir||T35552 adenylate kinase - Streptomyces coelicolor (fragment... 89 6e-17 pir||S74491 adenylate kinase (EC 2.7.4.3) 1 - Synechocystis sp. ... 88 1e-16 gb|AAD00547.1| (U83616) UMP-CMP kinase [Entamoeba histolytica] 87 2e-16 sp|P38372|KAD_BACHD ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 87 2e-16 sp|P25824|KAD_SCHMA ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE... 86 4e-16 emb|CAC12706.1| (AL136231) bA6J24.5 (Adenylate kinase 3 alpha) [... 82 4e-15 gb|AAC28787.1| (AF047722) adenylate kinase [Trypanosoma brucei r... 81 1e-14 gi|11424506 adenylate kinase 5 [Homo sapiens] 81 1e-14 gb|AAF49942.1| (AE003542) CG17146 gene product [Drosophila melan... 80 2e-14 gi|6912232 adenylate kinase 5 [Homo sapiens] >gi|9296996|sp|Q9Y6... 80 3e-14 dbj|BAA14303.1| (D90259) adenylate kinase [Escherichia coli] 76 3e-13 dbj|BAA28693.1| (AB005742) UMP-CMP kinase [Lentinula edodes] 76 4e-13 gb|AAF56560.1| (AE003754) Dak1 gene product [Drosophila melanoga... 76 4e-13 dbj|BAA86920.1| (AB025924) Dak1 [Drosophila melanogaster] >gi|64... 75 8e-13 pir||JC6572 cytidylate kinase (EC 2.7.4.14) - shiitake mushroom 73 2e-12 >sp|Q9UZN1|KAD_PYRAB ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|7434603|pir||E75090 adenylate kinase (EC 2.7.4.3) PAB0739 - Pyrococcus abyssi (strain Orsay) >gi|5458538|emb|CAB50026.1| (AJ248286) adenylate kinase (adk) (EC 2.7.4.3) [Pyrococcus abyssi] Length = 220 Score = 455 bits (1157), Expect = e-127 Identities = 220/220 (100%), Positives = 220/220 (100%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP Sbjct: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 Query: 61 DTIVNTLIISKLRRVRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVR 120 DTIVNTLIISKLRRVRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVR Sbjct: 61 DTIVNTLIISKLRRVRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVR 120 Query: 121 RISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPI 180 RISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPI Sbjct: 121 RISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPI 180 Query: 181 IKFYQKQGIYVRIDGHGSIDEVWERIRPLLDYIYNQENRR 220 IKFYQKQGIYVRIDGHGSIDEVWERIRPLLDYIYNQENRR Sbjct: 181 IKFYQKQGIYVRIDGHGSIDEVWERIRPLLDYIYNQENRR 220 >sp|O58844|KAD_PYRHO ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|7434605|pir||F71052 probable adenylate kinase - Pyrococcus horikoshii >gi|3257533|dbj|BAA30216.1| (AP000005) 220aa long hypothetical adenylate kinase [Pyrococcus horikoshii] Length = 220 Score = 430 bits (1093), Expect = e-120 Identities = 202/220 (91%), Positives = 215/220 (96%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 MNILIFGPPGSGKSTQARRITERYGLTYI+SGDIIRAEI +RTPLG+EME+YLSRGDLIP Sbjct: 1 MNILIFGPPGSGKSTQARRITERYGLTYISSGDIIRAEISSRTPLGLEMEKYLSRGDLIP 60 Query: 61 DTIVNTLIISKLRRVRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVR 120 DTIVNTLIISKLRRVRENFIMDGYPRTPEQVI LENYLYDHGIK+DVAIDI+ITKEESVR Sbjct: 61 DTIVNTLIISKLRRVRENFIMDGYPRTPEQVIALENYLYDHGIKIDVAIDIFITKEESVR 120 Query: 121 RISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPI 180 RISGRRICSKCGAVYH+EFNPPK+PGKCDICGG+LIQRPDDRPEIVEKRYDIY +NMEPI Sbjct: 121 RISGRRICSKCGAVYHIEFNPPKIPGKCDICGGDLIQRPDDRPEIVEKRYDIYMRNMEPI 180 Query: 181 IKFYQKQGIYVRIDGHGSIDEVWERIRPLLDYIYNQENRR 220 IKFYQKQGIYV+IDGHGSI+EVWERIRPLLDYIYN +RR Sbjct: 181 IKFYQKQGIYVKIDGHGSINEVWERIRPLLDYIYNTRSRR 220 >gi|11498284 adenylate kinase (adk) [Archaeoglobus fulgidus] >gi|9910707|sp|O29581|KAD_ARCFU ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|7434598|pir||D69334 adenylate kinase (EC 2.7.4.3) - Archaeoglobus fulgidus >gi|2649941|gb|AAB90565.1| (AE001058) adenylate kinase (adk) [Archaeoglobus fulgidus] Length = 217 Score = 205 bits (516), Expect = 4e-52 Identities = 92/215 (42%), Positives = 144/215 (66%), Gaps = 2/215 (0%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 MN++ GPPG+GK TQA+R++E+YG+ I++GD++R + T LG + + Y+ +G+L+P Sbjct: 1 MNLIFLGPPGAGKGTQAKRVSEKYGIPQISTGDMLREAVAKGTELGKKAKEYMDKGELVP 60 Query: 61 DTIVNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 D +V ++ +L++ + FI+DG+PRT Q L+ L + K+D I++ + +EE Sbjct: 61 DEVVIGIVKERLQQPDCEKGFILDGFPRTLAQAEALDEMLKELNKKIDAVINVVVPEEEV 120 Query: 119 VRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNME 178 V+RI+ RR C CGAVYH+ + PPK KCD CGGEL QR DD+ E V +RY +Y +N E Sbjct: 121 VKRITYRRTCRNCGAVYHLIYAPPKEDNKCDKCGGELYQRDDDKEETVRERYRVYKQNTE 180 Query: 179 PIIKFYQKQGIYVRIDGHGSIDEVWERIRPLLDYI 213 P+I +Y+K+GI +DG I+ VW+ I +L+ I Sbjct: 181 PLIDYYRKKGILYDVDGTKDIEGVWKEIEAILEKI 215 >sp|P16304|KAD_BACSU ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) (SUPEROXIDE-INDUCIBLE PROTEIN 16) (SOI16) >gi|80236|pir||JS0492 adenylate kinase (EC 2.7.4.3) - Bacillus subtilis >gi|216340|dbj|BAA00496.1| (D00619) adenylate kinase [Bacillus subtilis] >gi|1044985|gb|AAB06820.1| (L47971) adenylate kinase [Bacillus subtilis] >gi|2632404|emb|CAB11913.1| (Z99104) adenylate kinase [Bacillus subtilis] Length = 217 Score = 195 bits (490), Expect = 4e-49 Identities = 88/212 (41%), Positives = 135/212 (63%), Gaps = 2/212 (0%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 MN+++ G PG+GK TQ RI E YG+ +I++GD+ RA +K TPLG+E + Y+ +G+L+P Sbjct: 1 MNLVLMGLPGAGKGTQGERIVEDYGIPHISTGDMFRAAMKEETPLGLEAKSYIDKGELVP 60 Query: 61 DTIVNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 D + ++ +L + F++DG+PRT Q LE L ++G +D I+I + K+ Sbjct: 61 DEVTIGIVKERLGKDDCERGFLLDGFPRTVAQAEALEEILEEYGKPIDYVINIEVDKDVL 120 Query: 119 VRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNME 178 + R++GRRICS CG YH+ FNPPK PG CD GGEL QR DD E V KR ++ K + Sbjct: 121 MERLTGRRICSVCGTTYHLVFNPPKTPGICDKDGGELYQRADDNEETVSKRLEVNMKQTQ 180 Query: 179 PIIKFYQKQGIYVRIDGHGSIDEVWERIRPLL 210 P++ FY ++G ++G I +V+ ++ LL Sbjct: 181 PLLDFYSEKGYLANVNGQQDIQDVYADVKDLL 212 >sp|P27142|KAD_BACST ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|66939|pir||KIBSAF adenylate kinase (EC 2.7.4.3) - Bacillus stearothermophilus >gi|2392647|pdb|1ZIN| Adenylate Kinase With Bound Ap5a >gi|2392649|pdb|1ZIP| Bacillus Stearothermophilus Adenylate Kinase >gi|2392648|pdb|1ZIO| Phosphotransferase >gi|142446|gb|AAA22205.1| (M88104) adenylate kinase [Bacillus stearothermophilus] Length = 217 Score = 194 bits (487), Expect = 1e-48 Identities = 90/212 (42%), Positives = 137/212 (64%), Gaps = 2/212 (0%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 MN+++ G PG+GK TQA +I YG+ +I++GD+ RA +K TPLG++ ++Y+ RGDL+P Sbjct: 1 MNLVLMGLPGAGKGTQAEKIVAAYGIPHISTGDMFRAAMKEGTPLGLQAKQYMDRGDLVP 60 Query: 61 DTIVNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 D + ++ +L + + F++DG+PRT Q LE L D G KLD I I + ++ Sbjct: 61 DEVTIGIVRERLSKDDCQNGFLLDGFPRTVAQAEALETMLADIGRKLDYVIHIDVRQDVL 120 Query: 119 VRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNME 178 + R++GRRIC CGA YH+ F+PP PG CD CGGEL QR DD V R ++ K M+ Sbjct: 121 MERLTGRRICRNCGATYHLIFHPPAKPGVCDKCGGELYQRADDNEATVANRLEVNMKQMK 180 Query: 179 PIIKFYQKQGIYVRIDGHGSIDEVWERIRPLL 210 P++ FY+++G I+G +++V+ IR LL Sbjct: 181 PLVDFYEQKGYLRNINGEQDMEKVFADIRELL 212 >pir||T44404 adenylate kinase (EC 2.7.4.3) [imported] - Bacillus halodurans >gi|4512425|dbj|BAA75292.1| (AB017508) adk homologue (identity of 72% to B. subtilis ) [Bacillus halodurans] >gi|10172767|dbj|BAB03874.1| (AP001507) adenylate kinase [Bacillus halodurans] Length = 217 Score = 182 bits (458), Expect = 2e-45 Identities = 88/212 (41%), Positives = 135/212 (63%), Gaps = 2/212 (0%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 MN+++ G PG+GK TQA +I E+YG+ +I++GD+ RA +K T LG++ + Y+ G+L+P Sbjct: 1 MNLILMGLPGAGKGTQAEKIIEKYGIPHISTGDMFRAAMKNETELGLKAKSYMDAGELVP 60 Query: 61 DTIVNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 D + ++ +L + + F++DG+PRT Q LE+ L KLD I+I + ++ Sbjct: 61 DEVTIGIVRDRLSQDDCQNGFLLDGFPRTVAQAEALEDILASLDKKLDYVINIDVPEQLL 120 Query: 119 VRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNME 178 + R++GRR+ G YHV FNPPKV G CD+ G ELIQR DD+PE V+KR ++ K + Sbjct: 121 MDRLTGRRVSPTSGRTYHVIFNPPKVEGICDVDGSELIQRDDDKPETVKKRLEVNQKQAQ 180 Query: 179 PIIKFYQKQGIYVRIDGHGSIDEVWERIRPLL 210 P+I FY ++G I+G I V+E I LL Sbjct: 181 PLIDFYSEKGYLQNINGDQDISRVFEDINELL 212 >sp|P27143|KAD_LACLA ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|97972|pir||S17987 adenylate kinase (EC 2.7.4.3) - Lactococcus lactis subsp. lactis >gi|322101|pir||B44812 adenylate kinase (EC 2.7.4.3) - Lactococcus lactis >gi|44074|emb|CAA41940.1| (X59250) adenylate kinase [Lactococcus lactis] Length = 215 Score = 179 bits (450), Expect = 2e-44 Identities = 89/214 (41%), Positives = 131/214 (60%), Gaps = 4/214 (1%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 MN+LI G PG+GK TQA I + YG+ +I++GD+ RA +K T +G + ++ +G+L+P Sbjct: 1 MNLLIMGLPGAGKGTQAEFIVKNYGVNHISTGDMFRAAMKNETEMGKLAKSFIDKGELVP 60 Query: 61 DTIVNTLIISKLRR---VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEE 117 D + N ++ +L + F++DGYPRT +Q L+ L + GIKLD ++I + Sbjct: 61 DEVTNGIVKERLAQDDIKASGFLLDGYPRTIDQAHALDTMLEELGIKLDAVVNIVVNPNI 120 Query: 118 SVRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGG-ELIQRPDDRPEIVEKRYDIYSKN 176 V R+SGR IC CGA YH FNP KV G CD+CG +L QR DD PE V+ R D+ K Sbjct: 121 LVDRLSGRYICRNCGATYHKIFNPTKVEGTCDVCGSHDLYQRADDVPETVKNRLDVNIKE 180 Query: 177 MEPIIKFYQKQGIYVRIDGHGSIDEVWERIRPLL 210 PII+ Y + G+ I+G I +V + I+ +L Sbjct: 181 SAPIIEHYTELGLVKNIEGEQEISQVTDDIKKVL 214 >sp|P43414|KAD_STRCO ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|2924292|emb|CAA58138.1| (X83011) AdK adenylate kinase [Streptomyces coelicolor] Length = 217 Score = 175 bits (440), Expect = 3e-43 Identities = 84/208 (40%), Positives = 127/208 (60%), Gaps = 3/208 (1%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 M I++ GPPG+GK TQA R+ E + +I++GD+ RA I +T LG + Y++ G+L+P Sbjct: 1 MRIVLVGPPGAGKGTQATRLAETLHIPHISTGDLFRANISQQTELGKLAKSYMNAGNLVP 60 Query: 61 DTIVNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 D + + ++ + F++DG+PR Q L+ L G+KLD +D+ ++E Sbjct: 61 DEVTIAMAKDRMEQPDAEGGFLLDGFPRNVSQAEALDELLETEGMKLDAVLDLEAPEDEV 120 Query: 119 VRRISGRRIC-SKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNM 177 V+RI+GRR+C ++ V+HV + PPK G CD+CGGEL QR DD E V KR ++Y Sbjct: 121 VKRIAGRRVCRNEPKHVFHVTYTPPKKEGVCDVCGGELYQRDDDSEETVRKRLEVYHTQT 180 Query: 178 EPIIKFYQKQGIYVRIDGHGSIDEVWER 205 EPII +Y+ QG+ I G +DEV R Sbjct: 181 EPIIDYYKSQGLVATIAATGPVDEVTRR 208 >gb|AAG19963.1| (AE005078) adenylate kinase; Adk [Halobacterium sp. NRC-1] Length = 216 Score = 171 bits (430), Expect = 5e-42 Identities = 78/214 (36%), Positives = 131/214 (60%), Gaps = 10/214 (4%) Query: 2 NILIFGPPGSGKSTQARRITERYGLTYIASGDIIRA-EIKARTPLGIEMER---YLSRGD 57 N+L+ G PG+GK TQ+RR+ + +G+ ++ +GD +RA + K T L +E + Y+ G+ Sbjct: 5 NVLLLGAPGAGKGTQSRRLVDEFGVEHVTTGDALRANKTKDITHLDVEYDTPGAYMDAGE 64 Query: 58 LIPDTIVNTLIISKLRRVRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEE 117 L+PD +VN ++ + L + +++DGYPR Q L++ LDV + + + ++E Sbjct: 65 LVPDAVVNEIVKTALDDA-DGYVLDGYPRNESQTEYLDSIT-----DLDVVLYLDVDEDE 118 Query: 118 SVRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNM 177 V R++GRR+C CGA +HV FN P+ G CD CGG L QR DD E +R +Y +N Sbjct: 119 LVGRLTGRRVCEDCGATFHVSFNQPETEGVCDACGGSLYQREDDTEETARERITVYEENT 178 Query: 178 EPIIKFYQKQGIYVRIDGHGSIDEVWERIRPLLD 211 P+++++++QG+ +DG + DEVW + +D Sbjct: 179 APVVEYFREQGVLAEVDGERTPDEVWTDVAAAVD 212 >pir||JC5039 adenylate kinase (EC 2.7.4.3) - Halobacterium salinarum Length = 216 Score = 171 bits (428), Expect = 8e-42 Identities = 78/214 (36%), Positives = 131/214 (60%), Gaps = 10/214 (4%) Query: 2 NILIFGPPGSGKSTQARRITERYGLTYIASGDIIRA-EIKARTPLGIEMER---YLSRGD 57 N+L+ G PG+GK TQ+RR+ + +G+ ++ +GD +RA + K T L +E + Y+ G+ Sbjct: 5 NVLLLGAPGAGKGTQSRRLVDEFGVEHVTTGDALRANKTKDITHLDVEYDTPGAYMDAGE 64 Query: 58 LIPDTIVNTLIISKLRRVRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEE 117 L+PD +VN ++ + L + +++DGYPR Q L++ LDV + + + ++E Sbjct: 65 LVPDAVVNEIVKTALDDA-DGYVLDGYPRNESQTEYLDSIT-----DLDVVLYLDVDEDE 118 Query: 118 SVRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNM 177 V R++GRR+C CGA +HV FN P+ G CD CGG L QR DD E +R +Y +N Sbjct: 119 LVGRLTGRRVCEDCGATFHVSFNQPETEGVCDACGGSLYQREDDTLETARERITVYEENT 178 Query: 178 EPIIKFYQKQGIYVRIDGHGSIDEVWERIRPLLD 211 P+++++++QG+ +DG + DEVW + +D Sbjct: 179 APVVEYFREQGVLAEVDGERTPDEVWTDVAAAVD 212 >pir||G83184 adenylate kinase PA3686 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9949850|gb|AAG07074.1|AE004788_4 (AE004788) adenylate kinase [Pseudomonas aeruginosa] Length = 215 Score = 166 bits (416), Expect = 2e-40 Identities = 85/214 (39%), Positives = 129/214 (59%), Gaps = 12/214 (5%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 M +++ G PG+GK TQAR ITE++G+ I++GD++RA +KA +PLG +++ + G L+ Sbjct: 1 MRVILLGAPGAGKGTQARFITEKFGIPQISTGDMLRAAVKAGSPLGQQVKGVMDSGGLVS 60 Query: 61 DTIVNTLIISKLRRV--RENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 D I+ LI ++ + F+ DG+PRT Q L+ D G+ +D ++I + EE Sbjct: 61 DDIIIALIKERITEADCAKGFLFDGFPRTIPQAEALK----DAGVTIDHVVEIAVDDEEI 116 Query: 119 VRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNME 178 V RI+GRR+ G VYH E NPPKV GK D+ G ELIQR DD+ E V R +Y + Sbjct: 117 VSRIAGRRVHPASGRVYHTEHNPPKVAGKDDVTGEELIQREDDKEETVRHRLSVYHSQTK 176 Query: 179 PIIKFYQKQGI------YVRIDGHGSIDEVWERI 206 P++ FYQK Y I G GS++++ ++ Sbjct: 177 PLVDFYQKLSAAEGTPKYHSIAGVGSVEQITAKV 210 >pir||S50007 adenylate kinase (EC 2.7.4.3) - Streptomyces coelicolor Length = 205 Score = 166 bits (416), Expect = 2e-40 Identities = 78/192 (40%), Positives = 120/192 (61%), Gaps = 3/192 (1%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 M I++ GPPG+GK TQA R+ E + +I++GD+ RA I +T LG + Y++ G+L+P Sbjct: 1 MRIVLVGPPGAGKGTQATRLAETLHIPHISTGDLFRANISQQTELGKLAKSYMNAGNLVP 60 Query: 61 DTIVNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 D + + ++ + F++DG+PR Q L+ L G+KLD +D+ ++E Sbjct: 61 DEVTIAMAKDRMEQPDAEGGFLLDGFPRNVSQAEALDELLETEGMKLDAVLDLEAPEDEV 120 Query: 119 VRRISGRRIC-SKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNM 177 V+RI+GRR+C ++ V+HV + PPK G CD+CGGEL QR DD E V KR ++Y Sbjct: 121 VKRIAGRRVCRNEPKHVFHVTYTPPKKEGVCDVCGGELYQRDDDSEETVRKRLEVYHTQT 180 Query: 178 EPIIKFYQKQGI 189 EPII +Y+ QG+ Sbjct: 181 EPIIDYYKSQGL 192 >sp|P33075|KAD1_SCHPO ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|322891|pir||S31338 adenylate kinase (EC 2.7.4.3) 1 - fission yeast (Schizosaccharomyces pombe) >gi|476901|pir||A46718 adenylate kinase (EC 2.7.4.3) 1 - fission yeast (Schizosaccharomyces pombe) >gi|5536|emb|CAA49826.1| (X70363) adenylate kinase [Schizosaccharomyces pombe] >gi|1204204|emb|CAA93553.1| (Z69727) adenylate kinase [Schizosaccharomyces pombe] Length = 220 Score = 164 bits (412), Expect = 6e-40 Identities = 79/214 (36%), Positives = 132/214 (60%), Gaps = 3/214 (1%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 M +++ GPPG+GK TQA I ++YG+ ++A+GD++R+++ +T LG E ++ + +G L+ Sbjct: 4 MRLILVGPPGAGKGTQAPNIQKKYGIAHLATGDMLRSQVARQTELGKEAKKIMDQGGLVS 63 Query: 61 DTIVNTLIISKLRR---VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEE 117 D IV +I ++ + FI+DG+PRT Q L L + + L+ +++ + E Sbjct: 64 DDIVTGMIKDEILNNPECKNGFILDGFPRTVVQAEKLTALLDELKLDLNTVLELQVDDEL 123 Query: 118 SVRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNM 177 VRRI+GR + G YH+EFNPPKVP K D+ G LIQR DD + + KR Y + Sbjct: 124 LVRRITGRLVHPGSGRSYHLEFNPPKVPMKDDVTGEPLIQRSDDNADALRKRLVTYHEQT 183 Query: 178 EPIIKFYQKQGIYVRIDGHGSIDEVWERIRPLLD 211 P+++FY+K+G + +D ++VWE+I +L+ Sbjct: 184 TPVVEFYKKKGKWAAVDAAQKPEQVWEQIVAILE 217 >emb|CAA12055.1| (AJ224658) adenylate kinase [Neocallimastix frontalis] Length = 231 Score = 162 bits (407), Expect = 2e-39 Identities = 84/221 (38%), Positives = 129/221 (58%), Gaps = 2/221 (0%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 + ++I GPPGSGK TQA ++ + Y + ++A+GD++RA +KA TP+G+E ++ + G L+ Sbjct: 10 LRMVIMGPPGSGKGTQAPKVKDTYCICHLATGDMLRAAVKAGTPIGMEAKKIMDAGGLVS 69 Query: 61 DTIVNTLIISKL--RRVRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 D IV LI L + R FI+DG+PRT Q L+ L KLD AI++ + Sbjct: 70 DEIVVNLIKENLDTKACRNGFILDGFPRTVAQAQKLDEMLEQRNQKLDTAIELTVDDSLL 129 Query: 119 VRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNME 178 +RI+GR + G YH FNPPKV GK DI G LIQR DD ++KR Y K Sbjct: 130 FKRITGRLVHPASGRSYHKIFNPPKVEGKDDITGEPLIQRSDDTEAALKKRLVAYHKQTV 189 Query: 179 PIIKFYQKQGIYVRIDGHGSIDEVWERIRPLLDYIYNQENR 219 P+ ++Y+K+GI+ +D VW +++ + +Q ++ Sbjct: 190 PVAEYYKKKGIWRGVDASQPPAAVWAQMQAIFSERKSQSSK 230 >pir||PC4230 adenylate kinase (EC 2.7.4.3) - Streptomyces lividans (fragment) Length = 199 Score = 162 bits (407), Expect = 2e-39 Identities = 83/202 (41%), Positives = 118/202 (58%), Gaps = 8/202 (3%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 M I++ GPPG+GK TQA R+ E + +I++GD+ RA I +T LG + Y+ G+L+P Sbjct: 1 MRIVLVGPPGAGKGTQATRLAETLHIPHISTGDLFRANISQQTELGKLAKSYMDAGNLVP 60 Query: 61 DTIV----NTLIISKLRRVRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKE 116 D + T S R F++DG+PR Q L+ L +KLD +D+ ++ Sbjct: 61 DEVTIAMDRTAWSSPTPRA---FLLDGFPRNVSQAEALDELLETEDMKLDAVLDLEAPED 117 Query: 117 ESVRRISGRRICSKCGA-VYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSK 175 E V+RI+GRR+C A V+HV + PPK G CD+CGGEL QR DD E V KR ++Y Sbjct: 118 EVVKRIAGRRVCRNDSAHVFHVTYTPPKKEGVCDVCGGELYQRDDDSEETVRKRLEVYHT 177 Query: 176 NMEPIIKFYQKQGIYVRIDGHG 197 EPII +Y+ QG+ I G Sbjct: 178 QTEPIIDYYKSQGLVATIAATG 199 >sp|P49974|KAD_STRLI ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|862998|gb|AAC44591.1| (U27324) adenylate kinase [Streptomyces lividans] Length = 200 Score = 162 bits (407), Expect = 2e-39 Identities = 83/202 (41%), Positives = 118/202 (58%), Gaps = 8/202 (3%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 M I++ GPPG+GK TQA R+ E + +I++GD+ RA I +T LG + Y+ G+L+P Sbjct: 1 MRIVLVGPPGAGKGTQATRLAETLHIPHISTGDLFRANISQQTELGKLAKSYMDAGNLVP 60 Query: 61 DTIV----NTLIISKLRRVRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKE 116 D + T S R F++DG+PR Q L+ L +KLD +D+ ++ Sbjct: 61 DEVTIAMDRTAWSSPTPRA---FLLDGFPRNVSQAEALDELLETEDMKLDAVLDLEAPED 117 Query: 117 ESVRRISGRRICSKCGA-VYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSK 175 E V+RI+GRR+C A V+HV + PPK G CD+CGGEL QR DD E V KR ++Y Sbjct: 118 EVVKRIAGRRVCRNDSAHVFHVTYTPPKKEGVCDVCGGELYQRDDDSEETVRKRLEVYHT 177 Query: 176 NMEPIIKFYQKQGIYVRIDGHG 197 EPII +Y+ QG+ I G Sbjct: 178 QTEPIIDYYKSQGLVATIAATG 199 >sp|O66490|KAD_AQUAE ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|7434594|pir||G70307 adenylate kinase (EC 2.7.4.3) - Aquifex aeolicus >gi|2982815|gb|AAC06438.1| (AE000672) adenylate kinase [Aquifex aeolicus] Length = 206 Score = 162 bits (406), Expect = 3e-39 Identities = 80/205 (39%), Positives = 131/205 (63%), Gaps = 9/205 (4%) Query: 3 ILIF-GPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPD 61 IL+F GPPG+GK TQA+R+ + G +I++GDI+R ++ TPLG + + Y+ RG+L+PD Sbjct: 2 ILVFLGPPGAGKGTQAKRLAKEKGFVHISTGDILREAVQKGTPLGKKAKEYMERGELVPD 61 Query: 62 TIVNTLIISKLRRVRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVRR 121 ++ L I ++ N I DG+PRT +Q L+ L G+K+D + + E + R Sbjct: 62 DLIIAL-IEEVFPKHGNVIFDGFPRTVKQAEALDEMLEKKGLKVDHVLLFEVPDEVVIER 120 Query: 122 ISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPII 181 +SGRRI + G VYHV++NPP G ++IQR DD+PE+++KR ++Y + P+I Sbjct: 121 LSGRRINPETGEVYHVKYNPPPP-------GVKVIQREDDKPEVIKKRLEVYREQTAPLI 173 Query: 182 KFYQKQGIYVRIDGHGSIDEVWERI 206 ++Y+K+GI ID ++EV+ ++ Sbjct: 174 EYYKKKGILRIIDASKPVEEVYRQV 198 >sp|Q9Z409|KAD_PSEPU ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|4520134|dbj|BAA75818.1| (AB024426) adenylate kinase [Pseudomonas putida] Length = 216 Score = 160 bits (400), Expect = 2e-38 Identities = 77/215 (35%), Positives = 129/215 (59%), Gaps = 13/215 (6%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 M +++ G PG+GK TQA+ ITE++G+ I++GD++RA +KA TPLG+E+++ + G L+ Sbjct: 1 MRVILLGAPGAGKGTQAKFITEKFGIPQISTGDMLRAAVKAGTPLGLELKKVMDAGQLVS 60 Query: 61 DTIVNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 D ++ +L+ ++ + + DG+PRT Q + G+ +D ++I + EE Sbjct: 61 DELIISLVKERIAQPDCANGCLFDGFPRTIPQA----EAMVAAGVDIDAVVEIAVDDEEI 116 Query: 119 VRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNME 178 V R++GRR+ G YH+++NPPKV GK D G +LIQR DD+ E V R +Y + Sbjct: 117 VGRMAGRRVHLASGRTYHIQYNPPKVEGKDDETGEDLIQRDDDKEETVRHRLSVYHSQTK 176 Query: 179 PIIKFYQKQGI-------YVRIDGHGSIDEVWERI 206 P++ FYQK Y I+G GS++ + ++ Sbjct: 177 PLVDFYQKLSAANGGKPKYSHIEGVGSVEAITAKV 211 >sp|Q9X1I8|KAD_THEMA ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|7434608|pir||G72247 adenylate kinase - Thermotoga maritima (strain MSB8) >gi|4982043|gb|AAD36545.1|AE001798_10 (AE001798) adenylate kinase [Thermotoga maritima] Length = 220 Score = 159 bits (398), Expect = 3e-38 Identities = 79/213 (37%), Positives = 127/213 (59%), Gaps = 3/213 (1%) Query: 3 ILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTP-LGIEMERYLSRGDLIPD 61 ++ GPPG+GK T A+R+ E G+ +I++GDI R +K LG +++ + RG+L+PD Sbjct: 5 LVFLGPPGAGKGTYAKRLQEITGIPHISTGDIFRDIVKKENDELGKKIKEIMERGELVPD 64 Query: 62 TIVNTLIISKL--RRVRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESV 119 +VN ++ +L + FI+DGYPRT Q L+ +L +L A+ + +E V Sbjct: 65 ELVNEVVKRRLSEKDCERGFILDGYPRTVAQAEFLDGFLKTQNKELTAAVLFEVPEEVVV 124 Query: 120 RRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEP 179 +R++ RRIC KCG +Y++ PPK CD C +L+QR DD+ E V RY +Y + +P Sbjct: 125 QRLTARRICPKCGRIYNLISLPPKEDELCDDCKVKLVQREDDKEETVRHRYKVYLEKTQP 184 Query: 180 IIKFYQKQGIYVRIDGHGSIDEVWERIRPLLDY 212 +I +Y K+GI R+DG ID V + ++ + Sbjct: 185 VIDYYDKKGILKRVDGTIGIDNVIAEVLKIIGW 217 >emb|CAA12057.1| (AJ224660) adenylate kinase [Piromyces sp. E2] Length = 231 Score = 158 bits (395), Expect = 6e-38 Identities = 81/211 (38%), Positives = 123/211 (57%), Gaps = 2/211 (0%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 + ++I GPPGSGK TQA ++ + Y + ++A+GD++RA +KA TP+G+E ++ + G L+ Sbjct: 10 LRMVIMGPPGSGKGTQAPKVKDTYCICHLATGDMLRAAVKAGTPIGLEAKKIMDAGGLVS 69 Query: 61 DTIVNTLIISKL--RRVRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 D IV LI L + R FI+DG+PRT Q L+ L KLD AI++ + Sbjct: 70 DEIVVNLIKENLDTKACRNGFILDGFPRTVAQAEKLDEMLEQRNQKLDTAIELTVDDSLL 129 Query: 119 VRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNME 178 +RI+GR + G YH FN PKV GK DI G +IQR DD ++KR Y K Sbjct: 130 FKRITGRLVHPASGRSYHKIFNSPKVEGKDDITGEPIIQRSDDTEAALKKRLAAYHKQTV 189 Query: 179 PIIKFYQKQGIYVRIDGHGSIDEVWERIRPL 209 P+ +Y+K+GI+ +D VW +++ + Sbjct: 190 PVADYYKKKGIWRGVDASQPPAAVWAQMQAI 220 >sp|P10772|KAD_PARDE ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|1498049|gb|AAB06328.1| (U64203) adenylate kinase [Paracoccus denitrificans] Length = 218 Score = 157 bits (394), Expect = 8e-38 Identities = 82/214 (38%), Positives = 123/214 (57%), Gaps = 1/214 (0%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 +NI++ GPPG+GK TQARR+ + GL +++GD++R + T +G + + RG+L+ Sbjct: 3 INIILLGPPGAGKGTQARRLIDERGLVQLSTGDMLREARSSGTEMGKRVAEVMDRGELVT 62 Query: 61 DTIVNTLIISKLRRVRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVR 120 D IV LI KL + + FI DG+PRT Q L+ + + ++D I++ + V Sbjct: 63 DEIVIGLIREKLGQGGKGFIFDGFPRTLAQADALQALMAEMDQRIDAVIEMRVDDAALVS 122 Query: 121 RISGRRICSKCGAVYHVEFNPPKVPGKCDICGG-ELIQRPDDRPEIVEKRYDIYSKNMEP 179 RISGR C CG VYH P K PGKCD+CG +L +R DD E ++ R Y K P Sbjct: 123 RISGRFTCGNCGEVYHDVTKPTKEPGKCDVCGSTDLRRRADDNEESLKTRLMEYYKKTSP 182 Query: 180 IIKFYQKQGIYVRIDGHGSIDEVWERIRPLLDYI 213 +I +Y +G +DG IDEV ++ ++D I Sbjct: 183 LIGYYYVKGNLNPVDGLAEIDEVAAQVAKVMDKI 216 >sp|P24323|KAD_HAEIN ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|1073819|pir||I64062 adenylate kinase (EC 2.7.4.3) - Haemophilus influenzae (strain Rd KW20) >gi|1573319|gb|AAC22010.1| (U32719) adenylate kinase (adk) [Haemophilus influenzae Rd] Length = 214 Score = 157 bits (393), Expect = 1e-37 Identities = 81/217 (37%), Positives = 126/217 (57%), Gaps = 11/217 (5%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 M I++ G PG+GK TQA+ I ++G+ I++GD+ RA IKA T LG + + + G L+P Sbjct: 1 MKIILLGAPGAGKGTQAQFIMNKFGIPQISTGDMFRAAIKAGTELGKQAKALMDEGKLVP 60 Query: 61 DTIVNTLIISKLRRV--RENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 D + L+ ++ + F++DG+PRT Q L+ D G+K+D ++ + E Sbjct: 61 DELTVALVKDRIAQADCTNGFLLDGFPRTIPQADALK----DSGVKIDFVLEFDVPDEVI 116 Query: 119 VRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNME 178 V R+SGRR+ G YH+ +NPPKV GK D+ G +LI R DD+PE V R +Y K Sbjct: 117 VERMSGRRVHQASGRSYHIVYNPPKVEGKDDVTGEDLIIRADDKPETVLDRLAVYHKQTS 176 Query: 179 PIIKFYQKQG-----IYVRIDGHGSIDEVWERIRPLL 210 P+I +YQ + Y R+DG ++EV + + +L Sbjct: 177 PLIDYYQAEAKAGNTQYFRLDGTQKVEEVSQELDKIL 213 >pir||S15290 adenylate kinase (EC 2.7.4.3) - Haemophilus influenzae >gi|43591|emb|CAA40570.1| (X57315) adenylate kinase [Haemophilus influenzae] Length = 214 Score = 157 bits (393), Expect = 1e-37 Identities = 81/217 (37%), Positives = 126/217 (57%), Gaps = 11/217 (5%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 M I++ G PG+GK TQA+ I ++G+ I++GD+ RA IKA T LG + + + G L+P Sbjct: 1 MKIILLGAPGAGKGTQAQFIMNKFGIPQISTGDMFRAAIKAGTELGKQAKALMDEGKLVP 60 Query: 61 DTIVNTLIISKLRRV--RENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 D + L+ ++ + F++DG+PRT Q L+ D G+K+D ++ + E Sbjct: 61 DELTVALVKDRIAQADCANGFLLDGFPRTIPQADALK----DSGVKIDFVLEFDVPDEVI 116 Query: 119 VRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNME 178 V R+SGRR+ G YH+ +NPPKV GK D+ G +LI R DD+PE V R +Y K Sbjct: 117 VERMSGRRVHQASGRSYHIVYNPPKVEGKDDVTGEDLIIRADDKPETVLDRLAVYHKQTS 176 Query: 179 PIIKFYQKQG-----IYVRIDGHGSIDEVWERIRPLL 210 P+I +YQ + Y R+DG ++EV + + +L Sbjct: 177 PLIDYYQAEAKAGNTQYFRLDGTQKVEEVSQELDKIL 213 >sp|P39068|KAD_BORPE ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|628628|pir||S43016 adenylate kinase (EC 2.7.4.3) - Bordetella pertussis >gi|453621|emb|CAA82801.1| (Z29715) adenylate kinase [Bordetella pertussis] Length = 218 Score = 156 bits (391), Expect = 2e-37 Identities = 79/220 (35%), Positives = 125/220 (55%), Gaps = 14/220 (6%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 M +++ GPPG+GK TQA +T+ YG+ I++GD++RA +KA TPLG+E ++ + G L+ Sbjct: 1 MRLILLGPPGAGKGTQAAFLTQHYGIPQISTGDMLRAAVKAGTPLGLEAKKVMDAGGLVS 60 Query: 61 DTIVNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 D ++ L+ +L + ++ DG+PRT Q L++ GI LD ++I + + + Sbjct: 61 DDLIIGLVRDRLTQPDCANGYLFDGFPRTIPQADALKSA----GIALDYVVEIEVPESDI 116 Query: 119 VRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNME 178 + R+S RR+ G YHV FNPPK G D+ G L+QR DDR E V R ++Y Sbjct: 117 IERMSERRVHPASGRSYHVRFNPPKAEGVDDVTGEPLVQRDDDREETVRHRLNVYQNQTR 176 Query: 179 PIIKFYQKQG--------IYVRIDGHGSIDEVWERIRPLL 210 P++ +Y Y +I G GS+DE+ R+ L Sbjct: 177 PLVDYYSSWAQSDAAAAPKYRKISGVGSVDEIKSRLSQAL 216 >gb|AAC41489.1| (L47154) adenylate kinase [Neisseria meningitidis] >gi|1088376|gb|AAC41507.1| (L47144) adenylate kinase [Neisseria meningitidis] >gi|1088378|gb|AAC41508.1| (L47142) adenylate kinase [Neisseria meningitidis] >gi|1088384|gb|AAC41511.1| (L47147) adenylate kinase [Neisseria meningitidis] >gi|1088386|gb|AAC41512.1| (L47148) adenylate kinase [Neisseria meningitidis] >gi|1088388|gb|AAC41513.1| (L47150) adenylate kinase [Neisseria meningitidis] >gi|1088396|gb|AAC41517.1| (L47153) adenylate kinase [Neisseria meningitidis] Length = 215 Score = 155 bits (389), Expect = 3e-37 Identities = 79/209 (37%), Positives = 126/209 (59%), Gaps = 11/209 (5%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 M L+ G PG+GK TQA+ IT +G+ I++GD++RA IKA TPLG+E ++ + +G L+ Sbjct: 1 MKALLLGAPGAGKGTQAQFITAAFGIPQISTGDMLRAAIKAGTPLGLEAKKIIDKGGLVR 60 Query: 61 DTIVNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 D I+ ++ ++ + + F+ DG+PRT Q + + G+ LD ++I + Sbjct: 61 DDIIIGMVKERIAQDDCKNGFLFDGFPRTLAQA----EAMVEAGVDLDAVVEIDVPDSVI 116 Query: 119 VRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNME 178 V R+SGRR+ G YHV +NPPKV GK D+ G +LIQR DD+ E V+KR +Y + E Sbjct: 117 VDRMSGRRVHLASGRTYHVTYNPPKVEGKDDVTGEDLIQRDDDKEETVKKRLAVYHEQTE 176 Query: 179 PIIKFYQK-----QGIYVRIDGHGSIDEV 202 ++ FY K Y+++DG +++ V Sbjct: 177 VLVDFYSKLEGEHAPKYIKVDGTQAVEAV 205 >gb|AAC41506.1| (L47143) adenylate kinase [Neisseria meningitidis] >gi|1088380|gb|AAC41509.1| (L47146) adenylate kinase [Neisseria meningitidis] >gi|1088390|gb|AAC41514.1| (L47149) adenylate kinase [Neisseria meningitidis] >gi|1088394|gb|AAC41516.1| (L47152) adenylate kinase [Neisseria meningitidis] Length = 215 Score = 155 bits (387), Expect = 5e-37 Identities = 79/209 (37%), Positives = 125/209 (59%), Gaps = 11/209 (5%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 M L+ G PG+GK TQA+ IT +G+ I++GD++RA IKA TPLG+E ++ + G L+ Sbjct: 1 MKALLLGAPGAGKGTQAQFITAAFGIPQISTGDMLRAAIKAGTPLGLEAKKIIDEGGLVR 60 Query: 61 DTIVNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 D I+ ++ ++ + + F+ DG+PRT Q + + G+ LD ++I + Sbjct: 61 DDIIIGMVKERIAQDDCKNGFLFDGFPRTLAQA----EAMVEAGVDLDAVVEIDVPDSVI 116 Query: 119 VRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNME 178 V R+SGRR+ G YHV +NPPKV GK D+ G +LIQR DD+ E V+KR +Y + E Sbjct: 117 VDRMSGRRVHLASGRTYHVTYNPPKVEGKDDVTGEDLIQRDDDKEETVKKRLAVYHEQTE 176 Query: 179 PIIKFYQK-----QGIYVRIDGHGSIDEV 202 ++ FY K Y+++DG +++ V Sbjct: 177 VLVDFYSKLEGEHAPKYIKVDGTQAVEAV 205 >pir||F81154 adenylate kinase NMB0823 [imported] - Neisseria meningitidis (group B strain MD58) >gi|1088362|gb|AAC41500.1| (L47135) adenylate kinase [Neisseria meningitidis] >gi|7226058|gb|AAF41236.1| (AE002435) adenylate kinase [Neisseria meningitidis MC58] Length = 215 Score = 155 bits (387), Expect = 5e-37 Identities = 79/209 (37%), Positives = 125/209 (59%), Gaps = 11/209 (5%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 M L+ G PG+GK TQA+ IT +G+ I++GD++RA IKA TPLG+E ++ + G L+ Sbjct: 1 MKALLLGAPGAGKGTQAQFITAAFGIPQISTGDMLRAAIKAGTPLGLEAKKIIDEGGLVR 60 Query: 61 DTIVNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 D I+ ++ ++ + + F+ DG+PRT Q + + G+ LD ++I + Sbjct: 61 DDIIIGMVKERIAQDDCKNGFLFDGFPRTLAQA----EAMVEAGVDLDAVVEIDVPDSVI 116 Query: 119 VRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNME 178 V R+SGRR+ G YHV +NPPKV GK D+ G +LIQR DD+ E V+KR +Y + E Sbjct: 117 VDRMSGRRVHLASGRTYHVTYNPPKVEGKDDVTGEDLIQRDDDKEETVKKRLAVYHEQTE 176 Query: 179 PIIKFYQK-----QGIYVRIDGHGSIDEV 202 ++ FY K Y+++DG +++ V Sbjct: 177 VLVDFYSKLEGEHAPKYIKVDGTQAVEAV 205 >sp|P49980|KAD_NEIMA ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|2120884|pir||S61841 adenylate kinase (EC 2.7.4.3) [similarity] - Neisseria meningitidis (group B strain MD58, group A strain Z2491, strain P63, ATCC 43831) >gi|845612|gb|AAA99172.1| (L36469) adenylate kinase [Neisseria meningitidis] >gi|845614|gb|AAA99173.1| (L36470) adenylate kinase [Neisseria meningitidis] >gi|1088344|gb|AAC41491.1| (L47157) adenylate kinase [Neisseria meningitidis] >gi|1088348|gb|AAC41493.1| (L47155) adenylate kinase [Neisseria meningitidis] >gi|1088350|gb|AAC41494.1| (L47131) adenylate kinase [Neisseria meningitidis] >gi|1088354|gb|AAC41496.1| (L47133) adenylate kinase [Neisseria meningitidis] >gi|1088356|gb|AAC41497.1| (L47132) adenylate kinase [Neisseria meningitidis] >gi|1088358|gb|AAC41498.1| (L47134) adenylate kinase [Neisseria meningitidis] >gi|1088360|gb|AAC41499.1| (L47136) adenylate kinase [Neisseria meningitidis] >gi|1088364|gb|AAC41501.1| (L47137) adenylate kinase [Neisseria meningitidis] >gi|1088366|gb|AAC41502.1| (L47138) adenylate kinase [Neisseria meningitidis] >gi|1088368|gb|AAC41503.1| (L47139) adenylate kinase [Neisseria meningitidis] >gi|1088370|gb|AAC41504.1| (L47140) adenylate kinase [Neisseria meningitidis] >gi|1088372|gb|AAC41505.1| (L47141) adenylate kinase [Neisseria meningitidis] >gi|1088392|gb|AAC41515.1| (L47151) adenylate kinase [Neisseria meningitidis] >gi|7379734|emb|CAB84301.1| (AL162754) adenylate kinase [Neisseria meningitidis Z2491] Length = 215 Score = 154 bits (385), Expect = 9e-37 Identities = 79/209 (37%), Positives = 124/209 (58%), Gaps = 11/209 (5%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 M L+ G PG+GK TQA+ IT +G+ I++GD++RA IKA TPLG+E ++ + G L+ Sbjct: 1 MKALLLGAPGAGKGTQAQFITAAFGIPQISTGDMLRAAIKAGTPLGLEAKKIIDEGGLVR 60 Query: 61 DTIVNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 D I+ ++ ++ + + F+ DG+PRT Q + + G+ LD ++I + Sbjct: 61 DDIIIGMVKERIAQDDCKNGFLFDGFPRTLAQA----EAMVEAGVDLDAVVEIDVPDSVI 116 Query: 119 VRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNME 178 V R+SGRR+ G YHV +NPPKV GK D+ G +LIQR DD+ E V+KR +Y + E Sbjct: 117 VDRMSGRRVHLASGRTYHVTYNPPKVEGKDDVTGEDLIQRDDDKEETVKKRLAVYHEQTE 176 Query: 179 PIIKFYQK-----QGIYVRIDGHGSIDEV 202 ++ FY K Y+++DG ++ V Sbjct: 177 VLVDFYSKLEGEHAPKYIKVDGTQPVEAV 205 >sp|P49979|KAD_NEIGO ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|2120870|pir||S61843 adenylate kinase (EC 2.7.4.3) - Neisseria gonorrhoeae (strain CH-95) >gi|845616|gb|AAA99174.1| (L36471) adenylate kinase [Neisseria gonorrhoeae] Length = 215 Score = 153 bits (384), Expect = 1e-36 Identities = 78/209 (37%), Positives = 125/209 (59%), Gaps = 11/209 (5%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 M L+ G PG+GK TQA+ IT +G+ I++GD++RA IKA TPLG+E ++ + G L+ Sbjct: 1 MKALLLGAPGAGKGTQAQFITAAFGIPQISTGDMLRAAIKAGTPLGLEAKKIIDEGGLVR 60 Query: 61 DTIVNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 D I+ ++ ++ + + F+ DG+PRT Q + + G+ LD ++I ++ Sbjct: 61 DDIIIGMVKERIAQDDCKNGFLFDGFPRTLAQA----EAMVEAGVGLDAVVEIDVSDSVI 116 Query: 119 VRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNME 178 V R+SGRR+ G YHV +NPPK GK D+ G +LIQR DD+ E V+KR +Y + E Sbjct: 117 VDRMSGRRVHLASGRTYHVTYNPPKTEGKDDVTGEDLIQRDDDKEETVKKRLAVYHEQTE 176 Query: 179 PIIKFYQK-----QGIYVRIDGHGSIDEV 202 ++ FY K Y+++DG +++ V Sbjct: 177 VLVDFYSKLEGEHAPKYIKVDGTQAVEAV 205 >gb|AAC41492.1| (L47158) adenylate kinase [Neisseria meningitidis] >gi|1088352|gb|AAC41495.1| (L47130) adenylate kinase [Neisseria meningitidis] Length = 215 Score = 153 bits (383), Expect = 2e-36 Identities = 79/209 (37%), Positives = 123/209 (58%), Gaps = 11/209 (5%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 M L G PG+GK TQA+ IT +G+ I++GD++RA IKA TPLG+E ++ + G L+ Sbjct: 1 MKALFLGAPGAGKGTQAQFITAAFGIPQISTGDMLRAAIKAGTPLGLEAKKIIDEGGLVR 60 Query: 61 DTIVNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 D I+ ++ ++ + + F+ DG+PRT Q + + G+ LD ++I + Sbjct: 61 DDIIIGMVKERIAQDDCKNGFLFDGFPRTLAQA----EAMVEAGVDLDAVVEIDVPDSVI 116 Query: 119 VRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNME 178 V R+SGRR+ G YHV +NPPKV GK D+ G +LIQR DD+ E V+KR +Y + E Sbjct: 117 VDRMSGRRVHLASGRTYHVTYNPPKVEGKDDVTGEDLIQRDDDKEETVKKRLAVYHEQTE 176 Query: 179 PIIKFYQK-----QGIYVRIDGHGSIDEV 202 ++ FY K Y+++DG ++ V Sbjct: 177 VLVDFYSKLEGEHAPKYIKVDGTQPVEAV 205 >emb|CAA12056.1| (AJ224659) adenylate kinase [Neocallimastix frontalis] Length = 232 Score = 152 bits (381), Expect = 3e-36 Identities = 82/222 (36%), Positives = 129/222 (57%), Gaps = 7/222 (3%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 + +++ GPPGSGK TQA ++ + Y + ++A+GD++RA +KA TP+G+E ++ + G L+ Sbjct: 10 LRMVVMGPPGSGKGTQAPKVKDTYCICHLATGDMLRAAVKAGTPIGMEAKKIMDAGGLVS 69 Query: 61 DTIVNTLIISKL--RRVRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 D IV LI L + + FI+DG+PRT Q L+ L KLD AI++ + Sbjct: 70 DEIVVNLIKENLDTKACKNGFILDGFPRTVAQAQKLDEMLEQRNQKLDTAIELTVDDSLL 129 Query: 119 VRRISGRRICSKCGAVYHVEFNP-PKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNM 177 +RI+GR + G YH FNP KV GK DI G LIQR DD ++KR Y K Sbjct: 130 FKRITGRLVHPASGRSYHKIFNPNQKVEGKDDITGEPLIQRSDDTEAALKKRLVAYHKQT 189 Query: 178 EPIIKFYQKQGIYVRIDGHGSIDEVWERIRPLLDYIYNQENR 219 P+ +Y+K+GI+ +D VW +++ I++++N+ Sbjct: 190 VPVADYYKKKGIWRGVDASQPPAAVWAQMQA----IFSEKNK 227 >emb|CAA68471.1| (Y00413) adenylate cyclase (AA 1 - 222) [Saccharomyces cerevisiae] Length = 222 Score = 152 bits (379), Expect = 5e-36 Identities = 78/209 (37%), Positives = 121/209 (57%), Gaps = 3/209 (1%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 + +++ GPPG+GK TQA + ER+ ++A+GD++R++I T LG+E ++ + +G L+ Sbjct: 7 IRMVLIGPPGAGKGTQAPNLQERFHAAHLATGDMLRSQIAKGTQLGLEAKKIMDQGGLVS 66 Query: 61 DTIVNTLIISKLRR---VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEE 117 D I+ +I +L + FI+DG+PRT Q L+ L + G L+ AI++ + E Sbjct: 67 DDIMVNMIKDELTNNPACKNGFILDGFPRTIPQAEKLDQMLKEQGTPLEKAIELKVDDEL 126 Query: 118 SVRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNM 177 V RI+GR I + G YH FNPPK K D+ G L+QR DD + ++KR Y Sbjct: 127 LVARITGRLIHPRSGRSYHKIFNPPKEDMKDDVTGEALVQRSDDNADALKKRLAAYHAQT 186 Query: 178 EPIIKFYQKQGIYVRIDGHGSIDEVWERI 206 EPI+ FY+K GI+ +D VW I Sbjct: 187 EPIVDFYKKTGIWAGVDASQPPATVWADI 215 >sp|P49981|KAD_NEIMU ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|1088342|gb|AAC41490.1| (L47156) adenylate kinase [Neisseria mucosa] >gi|1354919|gb|AAB49195.1| (U57901) adenylate kinase [Neisseria mucosa] Length = 215 Score = 152 bits (379), Expect = 5e-36 Identities = 77/209 (36%), Positives = 124/209 (58%), Gaps = 11/209 (5%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 M +L+ G PG+GK TQA+ IT +G+ I++GD++RA IKA PLG+E ++ + G L+ Sbjct: 1 MKVLLLGAPGAGKGTQAQFITAAFGIPQISTGDMLRAAIKAGAPLGLEAKKIIDEGGLVR 60 Query: 61 DTIVNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 D I+ ++ ++ + + F+ DG+PRT Q + + G+ LD ++I + Sbjct: 61 DDIIIGMVKERIAQDDCKNGFLFDGFPRTLAQA----EAMVEAGVDLDAVVEIDVPDSVI 116 Query: 119 VRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNME 178 V R+SGRR+ G +HV +NPPKV GK D+ G +LIQR DD+ E V+KR +Y + E Sbjct: 117 VDRMSGRRVHLASGRTHHVTYNPPKVEGKDDVTGEDLIQRDDDKEETVKKRLAVYHEQTE 176 Query: 179 PIIKFYQK-----QGIYVRIDGHGSIDEV 202 ++ FY K Y+++DG ++ V Sbjct: 177 VLVDFYSKLEGEHAPKYIKVDGTQPVEAV 205 >sp|Q08480|KADB_ORYSA ADENYLATE KINASE B (ATP-AMP TRANSPHOSPHORYLASE) >gi|391879|dbj|BAA01181.1| (D10335) adenylate kinase-b [Oryza sativa] Length = 243 Score = 151 bits (378), Expect = 6e-36 Identities = 75/210 (35%), Positives = 123/210 (57%), Gaps = 2/210 (0%) Query: 3 ILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDT 62 +++ GPPGSGK TQ+ I + Y L ++A+GD++RA + A+TPLG++ + + +G+L+ D Sbjct: 33 LILVGPPGSGKGTQSPIIKDEYCLCHLATGDMLRAAVAAKTPLGVKAKEAMDKGELVSDD 92 Query: 63 IVNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVR 120 +V +I +++ ++ FI+DG+PRT Q L+ L G K+D ++ I Sbjct: 93 LVVGIIDEAMKKPSCQKGFILDGFPRTVVQAQKLDEMLEKKGTKVDKVLNFAIDDSILEE 152 Query: 121 RISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPI 180 RI+GR I G YH +F PPKVPG D+ G LIQR DD E+++ R + + K EP+ Sbjct: 153 RITGRWIHPSSGRSYHTKFAPPKVPGVDDVTGEPLIQRKDDTAEVLKSRLEAFHKQTEPV 212 Query: 181 IKFYQKQGIYVRIDGHGSIDEVWERIRPLL 210 I +Y K+ + + EV ++ +L Sbjct: 213 IDYYSKKALVANLHAEKPPKEVTAEVQKVL 242 >gb|AAC41510.1| (L47145) adenylate kinase [Neisseria meningitidis] Length = 215 Score = 151 bits (377), Expect = 8e-36 Identities = 78/209 (37%), Positives = 123/209 (58%), Gaps = 11/209 (5%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 M L+ G PG+GK TQA+ IT +G+ I++GD++RA IKA TPLG+E ++ + G L+ Sbjct: 1 MKALLLGAPGAGKGTQAQFITAAFGIPQISTGDMLRAAIKAGTPLGLEAKKIIDEGGLVR 60 Query: 61 DTIVNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 D I+ ++ ++ + + F+ DG+PRT Q + + G+ LD ++I + Sbjct: 61 DDIIIGMVKERIAQDDCKNGFLFDGFPRTLAQA----EAMVEAGVDLDAVVEIDVPDSVI 116 Query: 119 VRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNME 178 V R+SGRR+ G YHV +N PKV GK D+ G +LIQR DD+ E V+KR +Y + E Sbjct: 117 VDRMSGRRVHLASGRTYHVTYNSPKVEGKDDVTGEDLIQRDDDKEETVKKRLAVYHEQTE 176 Query: 179 PIIKFYQK-----QGIYVRIDGHGSIDEV 202 ++ FY K Y+++DG ++ V Sbjct: 177 VLVDFYSKLEGEHAPKYIKVDGTQPVEAV 205 >gi|6320432 adenylate kinase; Adk1p [Saccharomyces cerevisiae] >gi|125153|sp|P07170|KAD1_YEAST ADENYLATE KINASE CYTOSOLIC (ATP-AMP TRANSPHOSPHORYLASE) >gi|66937|pir||KIBYA adenylate kinase (EC 2.7.4.3) [validated] - yeast (Saccharomyces cerevisiae) >gi|3357|emb|CAA29624.1| (X06304) adenylate kinase (AA 1-222) [Saccharomyces cerevisiae] >gi|171032|gb|AAA66319.1| (M18455) adenylate kinase [Saccharomyces cerevisiae] >gi|532750|gb|AAC33143.1| (U13239) adenylate kinase [Saccharomyces cerevisiae] >gi|728682|emb|CAA88506.1| (Z48612) Adk1p [Saccharomyces cerevisiae] Length = 222 Score = 150 bits (376), Expect = 1e-35 Identities = 78/209 (37%), Positives = 120/209 (57%), Gaps = 3/209 (1%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 + +++ GPPG+GK TQA + ER+ ++A+GD++R++I T LG+E ++ + +G L+ Sbjct: 7 IRMVLIGPPGAGKGTQAPNLQERFHAAHLATGDMLRSQIAKGTQLGLEAKKIMDQGGLVS 66 Query: 61 DTIVNTLIISKLRR---VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEE 117 D I+ +I +L + FI+DG+PRT Q L+ L + G L+ AI++ + E Sbjct: 67 DDIMVNMIKDELTNNPACKNGFILDGFPRTIPQAEKLDQMLKEQGTPLEKAIELKVDDEL 126 Query: 118 SVRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNM 177 V RI+GR I G YH FNPPK K D+ G L+QR DD + ++KR Y Sbjct: 127 LVARITGRLIHPASGRSYHKIFNPPKEDMKDDVTGEALVQRSDDNADALKKRLAAYHAQT 186 Query: 178 EPIIKFYQKQGIYVRIDGHGSIDEVWERI 206 EPI+ FY+K GI+ +D VW I Sbjct: 187 EPIVDFYKKTGIWAGVDASQPPATVWADI 215 >pdb|1AKY| Atp:amp Phosphotransferase, Myokinase Mol_id: 1; Molecule: Adenylate Kinase; Chain: Null; Synonym: Atp:amp Phosphotransferase, Myokinase; Ec: 2.7.4.3; Heterogen: Ap5a; Heterogen: Imidazole >gi|1311097|pdb|2AKY| Atp:amp Phosphotransferase, Myokinase Mol_id: 1; Molecule: Adenylate Kinase; Chain: Null; Synonym: Atp:amp Phosphotransferase, Myokinase; Ec: 2.7.4.3; Heterogen: Ap5a; Heterogen: Mg Length = 221 Score = 150 bits (376), Expect = 1e-35 Identities = 78/209 (37%), Positives = 120/209 (57%), Gaps = 3/209 (1%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 + +++ GPPG+GK TQA + ER+ ++A+GD++R++I T LG+E ++ + +G L+ Sbjct: 6 IRMVLIGPPGAGKGTQAPNLQERFHAAHLATGDMLRSQIAKGTQLGLEAKKIMDQGGLVS 65 Query: 61 DTIVNTLIISKLRR---VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEE 117 D I+ +I +L + FI+DG+PRT Q L+ L + G L+ AI++ + E Sbjct: 66 DDIMVNMIKDELTNNPACKNGFILDGFPRTIPQAEKLDQMLKEQGTPLEKAIELKVDDEL 125 Query: 118 SVRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNM 177 V RI+GR I G YH FNPPK K D+ G L+QR DD + ++KR Y Sbjct: 126 LVARITGRLIHPASGRSYHKIFNPPKEDMKDDVTGEALVQRSDDNADALKKRLAAYHAQT 185 Query: 178 EPIIKFYQKQGIYVRIDGHGSIDEVWERI 206 EPI+ FY+K GI+ +D VW I Sbjct: 186 EPIVDFYKKTGIWAGVDASQPPATVWADI 214 >pdb|3AKY| Atp:amp Phosphotransferase, Myokinase Mol_id: 1; Molecule: Adenylate Kinase; Chain: Null; Synonym: Atp:amp Phosphotransferase, Myokinase; Ec: 2.7.4.3; Engineered: Yes; Mutation: I213f; Heterogen: Ap5a; Heterogen: Imidazole Length = 221 Score = 150 bits (375), Expect = 1e-35 Identities = 77/206 (37%), Positives = 119/206 (57%), Gaps = 3/206 (1%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 + +++ GPPG+GK TQA + ER+ ++A+GD++R++I T LG+E ++ + +G L+ Sbjct: 6 IRMVLIGPPGAGKGTQAPNLQERFHAAHLATGDMLRSQIAKGTQLGLEAKKIMDQGGLVS 65 Query: 61 DTIVNTLIISKLRR---VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEE 117 D I+ +I +L + FI+DG+PRT Q L+ L + G L+ AI++ + E Sbjct: 66 DDIMVNMIKDELTNNPACKNGFILDGFPRTIPQAEKLDQMLKEQGTPLEKAIELKVDDEL 125 Query: 118 SVRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNM 177 V RI+GR I G YH FNPPK K D+ G L+QR DD + ++KR Y Sbjct: 126 LVARITGRLIHPASGRSYHKIFNPPKEDMKDDVTGEALVQRSDDNADALKKRLAAYHAQT 185 Query: 178 EPIIKFYQKQGIYVRIDGHGSIDEVW 203 EPI+ FY+K GI+ +D VW Sbjct: 186 EPIVDFYKKTGIWAGVDASQPPATVW 211 >sp|O69172|KAD_YERPE ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|3153876|gb|AAC17436.1| (AF065382) adenylate kinase [Yersinia pestis] Length = 214 Score = 150 bits (375), Expect = 1e-35 Identities = 79/217 (36%), Positives = 128/217 (58%), Gaps = 11/217 (5%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 M I++ G PG+GK TQA+ I E+YG+ I++GD++RA +KA + LG++ + + G L+ Sbjct: 1 MRIILLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAVKAGSELGLKAKEIMDAGKLVT 60 Query: 61 DTIVNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 D +V L+ ++ + R+ F++DG+PRT Q ++ + GIK+D ++ + E Sbjct: 61 DELVIALVKERITQEDCRDGFLLDGFPRTIPQADAMK----EAGIKVDYVLEFDVPDELI 116 Query: 119 VRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNME 178 V RI GRR+ + G VYHV+FNPPKV K D+ G EL R DD+ V KR Y + Sbjct: 117 VERIVGRRVHAASGRVYHVKFNPPKVEDKDDVTGEELTIRKDDQEATVRKRLIEYHQQTA 176 Query: 179 PIIKFYQKQG-----IYVRIDGHGSIDEVWERIRPLL 210 P++ +Y K+ Y ++DG ++ EV + +L Sbjct: 177 PLVSYYHKEADAGNTQYFKLDGTRNVAEVSAELATIL 213 >pir||KIPC adenylate kinase (EC 2.7.4.3) - Paracoccus denitrificans Length = 217 Score = 149 bits (372), Expect = 3e-35 Identities = 80/214 (37%), Positives = 121/214 (56%), Gaps = 1/214 (0%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 +NI++ GPPG+GK TQARR+ + GL +++GD++R + T +G + + RG+L+ Sbjct: 2 INIILLGPPGAGKGTQARRLIDERGLVQLSTGDMLREARSSGTEMGKRVAEVMDRGELVT 61 Query: 61 DTIVNTLIISKLRRVRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVR 120 D IV LI KL + + FI DG+PRT Q L+ + + ++D I++ + V Sbjct: 62 DEIVIGLIREKLGQGGKGFIFDGFPRTLAQADALQALMAEMDQRIDAVIEMRVDDAALVS 121 Query: 121 RISGRRICSKCGAVYHVEFNPPKVPGKCDICGG-ELIQRPDDRPEIVEKRYDIYSKNMEP 179 RISGR CG VY P K PGKCD+CG +L +R DD E ++ R Y K P Sbjct: 122 RISGRFTHGNCGEVYGDVTKPTKEPGKCDVCGSTDLRRRADDNEESLKTRLMEYYKKTSP 181 Query: 180 IIKFYQKQGIYVRIDGHGSIDEVWERIRPLLDYI 213 +I +Y +G +DG IDEV ++ ++D I Sbjct: 182 LIGYYYVKGNLNPVDGLAEIDEVAAQVAKVMDKI 215 >gb|AAD45371.1|AF163320_1 (AF163320) type 2 adenylate kinase [Cryptosporidium parvum] Length = 220 Score = 149 bits (372), Expect = 3e-35 Identities = 80/212 (37%), Positives = 119/212 (55%), Gaps = 2/212 (0%) Query: 2 NILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPD 61 N+++ G PGSGK TQ I + YGL ++++GD++R IK T +G+E + + G+ + D Sbjct: 8 NLILIGAPGSGKGTQCEFIKKEYGLAHLSTGDMLREAIKNGTKIGLEAKSIIESGNFVGD 67 Query: 62 TIVNTLIISK--LRRVRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESV 119 IV L+ K L F++DG+PRT Q L L + G L I I E + Sbjct: 68 EIVLGLVKEKFDLGVCVNGFVLDGFPRTIPQAEGLAKILSEIGDSLTSVIYFEIDDSEII 127 Query: 120 RRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEP 179 RISGR G +YHV++NPPK PG D+ G L+ R DD E V+ R D++ K P Sbjct: 128 ERISGRCTHPASGRIYHVKYNPPKQPGIDDVTGEPLVWRDDDNAEAVKVRLDVFHKQTAP 187 Query: 180 IIKFYQKQGIYVRIDGHGSIDEVWERIRPLLD 211 ++KFY+ GI R++ EV E+I+ +L+ Sbjct: 188 LVKFYEDLGILKRVNAKLPPKEVTEQIKKILE 219 >sp|P05082|KAD_ECOLI ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|66938|pir||KIECA adenylate kinase (EC 2.7.4.3) [validated] - Escherichia coli >gi|493809|pdb|1AKE|A Chain A, Adenylate Kinase (E.C.2.7.4.3) Complex With The Inhibitor Ap5a >gi|493810|pdb|1AKE|B Chain B, Adenylate Kinase (E.C.2.7.4.3) Complex With The Inhibitor Ap5a >gi|576003|pdb|1ANK|A Chain A, Adenylate Kinase (Adk) (E.C.2.7.4.3) >gi|576004|pdb|1ANK|B Chain B, Adenylate Kinase (Adk) (E.C.2.7.4.3) >gi|1633462|pdb|4AKE|A Chain A, Adenylate Kinase >gi|1633463|pdb|4AKE|B Chain B, Adenylate Kinase >gi|1942106|pdb|2ECK|A Chain A, Structure Of Phosphotransferase >gi|1942107|pdb|2ECK|B Chain B, Structure Of Phosphotransferase >gi|40904|emb|CAA26840.1| (X03038) adenylate kinase (adk) (aa 1-214) [Escherichia coli] >gi|145301|gb|AAA23461.1| (M38777) adk ORF [Escherichia coli] >gi|1786680|gb|AAC73576.1| (AE000153) adenylate kinase activity; pleiotropic effects on glycerol-3-phosphate acyltransferase activity [Escherichia coli K12] Length = 214 Score = 147 bits (368), Expect = 9e-35 Identities = 80/217 (36%), Positives = 126/217 (57%), Gaps = 11/217 (5%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 M I++ G PG+GK TQA+ I E+YG+ I++GD++RA +K+ + LG + + + G L+ Sbjct: 1 MRIILLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAVKSGSELGKQAKDIMDAGKLVT 60 Query: 61 DTIVNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 D +V L+ ++ + R F++DG+PRT Q ++ + GI +D ++ + E Sbjct: 61 DELVIALVKERIAQEDCRNGFLLDGFPRTIPQADAMK----EAGINVDYVLEFDVPDELI 116 Query: 119 VRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNME 178 V RI GRR+ + G VYHV+FNPPKV GK D+ G EL R DD+ E V KR Y + Sbjct: 117 VDRIVGRRVHAPSGRVYHVKFNPPKVEGKDDVTGEELTTRKDDQEETVRKRLVEYHQMTA 176 Query: 179 PIIKFYQKQG-----IYVRIDGHGSIDEVWERIRPLL 210 P+I +Y K+ Y ++DG + EV + +L Sbjct: 177 PLIGYYSKEAEAGNTKYAKVDGTKPVAEVRADLEKIL 213 >sp|P37407|KAD_SALTY ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|425196|gb|AAA65969.1| (L26246) adenylate kinase [Salmonella typhimurium] Length = 214 Score = 147 bits (368), Expect = 9e-35 Identities = 79/217 (36%), Positives = 128/217 (58%), Gaps = 11/217 (5%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 M I++ G PG+GK TQA+ I E+YG+ I++GD++RA +K+ + LG + + + G L+ Sbjct: 1 MRIILLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAVKSGSELGKQAKDIMDAGKLVT 60 Query: 61 DTIVNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 D +V L+ ++ + R F++DG+PRT Q ++ + GI +D ++ + E Sbjct: 61 DELVIALVKERIAQEDCRNGFLLDGFPRTIPQADAMK----EAGIVVDYVLEFDVPDELI 116 Query: 119 VRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNME 178 V RI GRR+ + G VYHV+FNPPKV GK D+ G +L R DD+ E V KR Y + Sbjct: 117 VDRIVGRRVHAASGRVYHVKFNPPKVEGKDDVTGEDLTTRKDDQEETVRKRLVEYHQMTA 176 Query: 179 PIIKFYQKQG-----IYVRIDGHGSIDEVWERIRPLL 210 P+I +YQK+ Y ++DG ++ +V + +L Sbjct: 177 PLIGYYQKEAEAGNTKYAKVDGTQAVADVRAALEKIL 213 >gb|AAB40228.1| (U82664) adenylate kinase [Escherichia coli] Length = 233 Score = 147 bits (368), Expect = 9e-35 Identities = 80/217 (36%), Positives = 126/217 (57%), Gaps = 11/217 (5%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 M I++ G PG+GK TQA+ I E+YG+ I++GD++RA +K+ + LG + + + G L+ Sbjct: 20 MRIILLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAVKSGSELGKQAKDIMDAGKLVT 79 Query: 61 DTIVNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 D +V L+ ++ + R F++DG+PRT Q ++ + GI +D ++ + E Sbjct: 80 DELVIALVKERIAQEDCRNGFLLDGFPRTIPQADAMK----EAGINVDYVLEFDVPDELI 135 Query: 119 VRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNME 178 V RI GRR+ + G VYHV+FNPPKV GK D+ G EL R DD+ E V KR Y + Sbjct: 136 VDRIVGRRVHAPSGRVYHVKFNPPKVEGKDDVTGEELTTRKDDQEETVRKRLVEYHQMTA 195 Query: 179 PIIKFYQKQG-----IYVRIDGHGSIDEVWERIRPLL 210 P+I +Y K+ Y ++DG + EV + +L Sbjct: 196 PLIGYYSKEAEAGNTKYAKVDGTKPVAEVRADLEKIL 232 >emb|CAC18138.1| (AL451012) probable adenylate kinase [Neurospora crassa] Length = 236 Score = 147 bits (367), Expect = 1e-34 Identities = 76/212 (35%), Positives = 121/212 (56%), Gaps = 3/212 (1%) Query: 3 ILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDT 62 +++ GPPG+GK TQA +I E++ ++A+GD++RA++ T LG + ++ ++ G L+ D Sbjct: 1 MVLMGPPGAGKGTQAPKIKEKFNCCHLATGDMLRAQVAKGTALGKQAKKIMNEGGLVSDD 60 Query: 63 IVNTLIISKLRRVRE---NFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESV 119 IV +I +L +E FI+DG+PRT Q L+ L + + L A+++ I V Sbjct: 61 IVIGMIKDELENNKECQGGFILDGFPRTVPQAEGLDAMLRERNLPLQHAVELKIDDSLLV 120 Query: 120 RRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEP 179 RI+GR + G YH FNPPK K DI G L+QR DD E + KR + Y K P Sbjct: 121 ARITGRLVHPASGRSYHRIFNPPKDDMKDDITGEPLVQRSDDNAEALRKRLETYHKQTAP 180 Query: 180 IIKFYQKQGIYVRIDGHGSIDEVWERIRPLLD 211 ++ +YQ GI+ ID +VW+ + + + Sbjct: 181 VVGYYQNTGIWKAIDASQEPAQVWKSLLAIFE 212 >pir||C82255 adenylate kinase VC0986 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9655447|gb|AAF94147.1| (AE004180) adenylate kinase [Vibrio cholerae] Length = 214 Score = 146 bits (364), Expect = 3e-34 Identities = 77/209 (36%), Positives = 122/209 (57%), Gaps = 11/209 (5%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 M I++ G PG+GK TQA+ I E++G+ I++GD++RA IKA T LG + + + G L+ Sbjct: 1 MRIILLGAPGAGKGTQAQFIMEKFGIPQISTGDMLRAAIKAGTELGKQAKAVIDAGQLVS 60 Query: 61 DTIVNTLIISKLRRV--RENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 D I+ LI ++ + + F++DG+PRT Q L+ + GI +D I+ + + Sbjct: 61 DDIILGLIKERIAQADCEKGFLLDGFPRTIPQADGLK----EMGINVDYVIEFDVADDVI 116 Query: 119 VRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNME 178 V R++GRR G YHV +NPPKV GK D+ G +L+ R DD+ E V R ++Y Sbjct: 117 VERMAGRRAHLPSGRTYHVVYNPPKVEGKDDVTGEDLVIREDDKEETVRARLNVYHTQTA 176 Query: 179 PIIKFYQKQGI-----YVRIDGHGSIDEV 202 P+I++Y K+ Y++ DG + EV Sbjct: 177 PLIEYYGKEAAAGKTQYLKFDGTKQVSEV 205 >dbj|BAB09456.1| (AB012248) adenylate kinase [Arabidopsis thaliana] Length = 248 Score = 145 bits (363), Expect = 3e-34 Identities = 72/210 (34%), Positives = 123/210 (58%), Gaps = 2/210 (0%) Query: 3 ILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDT 62 ++ GPPGSGK TQ+ I + + L ++++GD++RA + A+TPLG++ + + +G+L+ D Sbjct: 37 LVFIGPPGSGKGTQSPVIKDEFCLCHLSTGDMLRAAVAAKTPLGVKAKEAMDKGELVSDD 96 Query: 63 IVNTLIISKLRRVR--ENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVR 120 +V ++ + R + + FI+DG+PRT Q L+ L G ++D ++ I Sbjct: 97 LVVGIMDEAMNRPKCQKGFILDGFPRTVTQAEKLDEMLNRRGAQIDKVLNFAIDDSVLEE 156 Query: 121 RISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPI 180 RI+GR I G YH +F PPKVPG D+ G LIQR DD +++ R D + K +P+ Sbjct: 157 RITGRWIHPSSGRSYHTKFAPPKVPGVDDLTGEPLIQRKDDNADVLRSRLDAFHKQTQPV 216 Query: 181 IKFYQKQGIYVRIDGHGSIDEVWERIRPLL 210 I +Y K+ V I + +EV + ++ ++ Sbjct: 217 IDYYAKKENLVNIPAEKAPEEVTKVVKKVV 246 >sp|O83604|KAD_TREPA ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|7434604|pir||D71306 probable adenylate kinase (adk) - syphilis spirochete >gi|3322887|gb|AAC65567.1| (AE001234) adenylate kinase (adk) [Treponema pallidum] Length = 211 Score = 145 bits (362), Expect = 4e-34 Identities = 76/204 (37%), Positives = 117/204 (57%), Gaps = 7/204 (3%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 M + GPPG+GK T A I+ R G+ +I++G I+RA I+ +T LG ++++ + G L+ Sbjct: 1 MRFVFLGPPGAGKGTLAGEISGRCGVVHISTGGILRAAIQKQTALGKKVQKVVEVGGLVD 60 Query: 61 DTIVNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 D V L+ ++ V FI+DG+PRT Q LE+ + +D A+ I + + Sbjct: 61 DQTVTELVRERVSHEDVVSGFILDGFPRTVTQARCLEDI-----VPIDYAVSIVVPDDVL 115 Query: 119 VRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNME 178 V R++GRR+CS CG+ YHV F PK G CD C G L+ R DD+ + +R Y E Sbjct: 116 VARLTGRRVCSACGSSYHVLFAQPKREGVCDRCRGVLVVREDDKMSAILQRLTAYRAQAE 175 Query: 179 PIIKFYQKQGIYVRIDGHGSIDEV 202 PI+ FY ++G V ++G I +V Sbjct: 176 PIVHFYSERGKLVSLNGAPPISDV 199 >gi|6321018 Adenylate kinase (mitochondrial GTP:AMP phosphotransferase); Adk2p [Saccharomyces cerevisiae] >gi|125155|sp|P26364|KAD2_YEAST ADENYLATE KINASE 2 (ATP-AMP TRANSPHOSPHORYLASE) >gi|101181|pir||S23568 adenylate kinase (EC 2.7.4.3) ADK2 - yeast (Saccharomyces cerevisiae) >gi|4097|emb|CAA46254.1| (X65126) adenylate kinase [Saccharomyces cerevisiae] >gi|171046|gb|AAA34418.1| (M77757) adenylate kinase 2 [Saccharomyces cerevisiae] >gi|603411|gb|AAB64697.1| (U18922) Adk2p: adenylate kinase 2 [Saccharomyces cerevisiae] Length = 225 Score = 145 bits (361), Expect = 6e-34 Identities = 74/204 (36%), Positives = 120/204 (58%), Gaps = 6/204 (2%) Query: 1 MNILIFGPPGSGKSTQARRITERYG-LTYIASGDIIRAEIKARTPLGIEMERYLSRGDLI 59 + +L+ G PGSGK TQ R+ ++ L+ I+SGDI+R EIK+ + LG E Y+++G L+ Sbjct: 15 LRLLLLGAPGSGKGTQTSRLLKQIPQLSSISSGDILRQEIKSESTLGREATTYIAQGKLL 74 Query: 60 PDTIVNTLIISKLRRV-----RENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYIT 114 PD ++ LI +L + +++DG+PRT Q L+ L H L++ +++ + Sbjct: 75 PDDLITRLITFRLSALGWLKPSAMWLLDGFPRTTAQASALDELLKQHDASLNLVVELDVP 134 Query: 115 KEESVRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYS 174 + + RI R + G VY++++NPPKVPG DI G L +R DD E+ +KR + Y Sbjct: 135 ESTILERIENRYVHVPSGRVYNLQYNPPKVPGLDDITGEPLTKRLDDTAEVFKKRLEEYK 194 Query: 175 KNMEPIIKFYQKQGIYVRIDGHGS 198 K EP+ +Y+K GI+ + G S Sbjct: 195 KTNEPLKDYYKKSGIFGTVSGETS 218 >sp|P33107|KAD_MICLU ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|322067|pir||S17070 adenylate kinase (EC 2.7.4.3) - Micrococcus luteus >gi|44436|emb|CAA35568.1| (X17524) Adk protein [Micrococcus luteus] Length = 205 Score = 144 bits (360), Expect = 8e-34 Identities = 76/215 (35%), Positives = 117/215 (54%), Gaps = 32/215 (14%) Query: 3 ILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDT 62 +L+ GPPGSGK TQA RI ++ G+ I++GDI R +K+ TPLG+E +RY+ GD +PD Sbjct: 4 MLLMGPPGSGKGTQATRIADKLGIVPISTGDIFRHNVKSMTPLGVEAKRYIDNGDFVPDE 63 Query: 63 IVNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVR 120 + N ++ ++ + F++DGYPRT QV L+ L + G L +++ + EE V Sbjct: 64 VTNRMVADRIAQADAEHGFLLDGYPRTKGQVEALDAMLAEAGQSLSAVVELEVPDEELVE 123 Query: 121 RISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPI 180 R+ R E+ R DD E++E R D+Y + E + Sbjct: 124 RLLKR---------------------------AEIEGRADDTQEVIEHRLDLYHRETESV 156 Query: 181 IKFYQKQGIYVRIDGHGSIDEVWERIRPLLDYIYN 215 I+ Y ++GI R+DG G ID+V ER LL +Y+ Sbjct: 157 IQEYVERGIVARVDGTGQIDDVTER---LLQAVYS 188 >sp|P34346|KADX_CAEEL PROBABLE ADENYLATE KINASE ISOENZYME C29E4.8 (ATP-AMP TRANSPHOSPHORYLASE) >gi|630556|pir||S44766 adenylate kinase (EC 2.7.4.3) - Caenorhabditis elegans >gi|388577|gb|AAA27957.1| (L23651) homology with adenylate kinase; putative [Caenorhabditis elegans] Length = 248 Score = 144 bits (360), Expect = 8e-34 Identities = 75/201 (37%), Positives = 114/201 (56%), Gaps = 2/201 (0%) Query: 4 LIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDTI 63 + GPPGSGK TQA ++Y ++A+GD++RAE+ + + G E++ + G L+ D + Sbjct: 30 IFIGPPGSGKGTQAPAFAQKYFSCHLATGDLLRAEVASGSEFGKELKATMDAGKLVSDEV 89 Query: 64 VNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVRR 121 V LI KL + + FI+DG+PRT Q L+ L LD ++ I + VRR Sbjct: 90 VCKLIEQKLEKPECKYGFILDGFPRTSGQAEKLDEILERRKTPLDTVVEFNIADDLLVRR 149 Query: 122 ISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPII 181 I+GR G YH+EF PPKVP K D+ G LI+R DD E + KR Y + P++ Sbjct: 150 ITGRLFHIASGRSYHLEFKPPKVPMKDDLTGEPLIRRSDDNEETLRKRLVQYHQMTVPLV 209 Query: 182 KFYQKQGIYVRIDGHGSIDEV 202 +Y+K G++V +D + +V Sbjct: 210 DYYKKHGVHVAVDAAKPMTDV 230 >sp|P08760|KAD3_BOVIN GTP:AMP PHOSPHOTRANSFERASE MITOCHONDRIAL (AK3) >gi|108504|pir||A34442 nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) 3, mitochondrial - bovine >gi|163528|gb|AAA30705.1| (M25757) GTP:AMP phosphotransferase (EC 2.7.4.10) [Bos taurus] >gi|217576|dbj|BAA01210.1| (D10376) mitochondrial adenylate kinase isozyme 3 [Bos taurus] Length = 227 Score = 144 bits (359), Expect = 1e-33 Identities = 72/207 (34%), Positives = 122/207 (58%), Gaps = 7/207 (3%) Query: 5 IFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDTIV 64 I G PGSGK T + RIT+ + L +++SGD++R + T +G+ + ++ +G LIPD ++ Sbjct: 12 IMGAPGSGKGTVSSRITKHFELKHLSSGDLLRDNMLRGTEIGVLAKTFIDQGKLIPDDVM 71 Query: 65 NTLIISKLRRVRE-NFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVRRIS 123 L++ +L+ + + N+++DG+PRT Q L D ++D I++ + E +R++ Sbjct: 72 TRLVLHELKNLTQYNWLLDGFPRTLPQAEAL-----DRAYQIDTVINLNVPFEVIKQRLT 126 Query: 124 GRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPIIKF 183 R I G VY++EFNPPK G D+ G L+QR DDRPE V KR Y EP++++ Sbjct: 127 ARWIHPGSGRVYNIEFNPPKTMGIDDLTGEPLVQREDDRPETVVKRLKAYEAQTEPVLEY 186 Query: 184 YQKQGIYVRIDGHGSIDEVWERIRPLL 210 Y+K+G+ G +++W + L Sbjct: 187 YRKKGVLETFSG-TETNKIWPHVYAFL 212 >pdb|2AK3|A Chain A, Adenylate Kinase Isoenzyme-3 (Gtp: Amp Phosphotransferase) (E.C.2.7.4.10) >gi|1065286|pdb|2AK3|B Chain B, Adenylate Kinase Isoenzyme-3 (Gtp: Amp Phosphotransferase) (E.C.2.7.4.10) Length = 226 Score = 144 bits (359), Expect = 1e-33 Identities = 72/207 (34%), Positives = 122/207 (58%), Gaps = 7/207 (3%) Query: 5 IFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDTIV 64 I G PGSGK T + RIT+ + L +++SGD++R + T +G+ + ++ +G LIPD ++ Sbjct: 11 IMGAPGSGKGTVSSRITKHFELKHLSSGDLLRDNMLRGTEIGVLAKTFIDQGKLIPDDVM 70 Query: 65 NTLIISKLRRVRE-NFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVRRIS 123 L++ +L+ + + N+++DG+PRT Q L D ++D I++ + E +R++ Sbjct: 71 TRLVLHELKNLTQYNWLLDGFPRTLPQAEAL-----DRAYQIDTVINLNVPFEVIKQRLT 125 Query: 124 GRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPIIKF 183 R I G VY++EFNPPK G D+ G L+QR DDRPE V KR Y EP++++ Sbjct: 126 ARWIHPGSGRVYNIEFNPPKTMGIDDLTGEPLVQREDDRPETVVKRLKAYEAQTEPVLEY 185 Query: 184 YQKQGIYVRIDGHGSIDEVWERIRPLL 210 Y+K+G+ G +++W + L Sbjct: 186 YRKKGVLETFSG-TETNKIWPHVYAFL 211 >pdb|1DVR|A Chain A, Nucleoside Monophosphate Kinase, Myokinase Mol_id: 1; Molecule: Adenylate Kinase; Chain: A, B; Synonym: Atp:amp-Phosphotransferase, Myokinase; Ec: 2.7.4.3; Engineered: Yes; Mutation: D89v, R165i >gi|1421659|pdb|1DVR|B Chain B, Nucleoside Monophosphate Kinase, Myokinase Mol_id: 1; Molecule: Adenylate Kinase; Chain: A, B; Synonym: Atp:amp-Phosphotransferase, Myokinase; Ec: 2.7.4.3; Engineered: Yes; Mutation: D89v, R165i Length = 220 Score = 144 bits (359), Expect = 1e-33 Identities = 76/209 (36%), Positives = 118/209 (56%), Gaps = 3/209 (1%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 + +++ GPPG+GK TQA + ER+ ++A+GD++R++I T LG+E ++ + +G L+ Sbjct: 5 IRMVLIGPPGAGKGTQAPNLQERFHAAHLATGDMLRSQIAKGTQLGLEAKKIMDQGGLVS 64 Query: 61 DTIVNTLIISKLRR---VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEE 117 D I+ +I +L + FI+ G+PRT Q L+ L + G L+ AI++ + E Sbjct: 65 DDIMVNMIKDELTNNPACKNGFILVGFPRTIPQAEKLDQMLKEQGTPLEKAIELKVDDEL 124 Query: 118 SVRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNM 177 V RI+GR I G YH FNPPK K D+ G L+Q DD + ++KR Y Sbjct: 125 LVARITGRLIHPASGRSYHKIFNPPKEDMKDDVTGEALVQISDDNADALKKRLAAYHAQT 184 Query: 178 EPIIKFYQKQGIYVRIDGHGSIDEVWERI 206 EPI+ FY+K GI+ +D VW I Sbjct: 185 EPIVDFYKKTGIWAGVDASQPPATVWADI 213 >sp|O51378|KAD_BORBU ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|7434602|pir||H70151 adenylate kinase (adk) homolog - Lyme disease spirochete >gi|2688315|gb|AAC66782.1| (AE001146) adenylate kinase (adk) [Borrelia burgdorferi] Length = 211 Score = 144 bits (359), Expect = 1e-33 Identities = 73/208 (35%), Positives = 122/208 (58%), Gaps = 7/208 (3%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 M ++ GPPGSGK T ++ I+ + +I++GD+ R I T LG E+++ + RG+L+P Sbjct: 1 MGLVFLGPPGSGKGTISKIISNEFKYQHISTGDLFRENILNSTALGQEIKKIVERGELVP 60 Query: 61 DTIVNTLIISKLRRVREN--FIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 D I ++ K++ +++N FI+DG+PR Q L+ +L + I I+ I +E Sbjct: 61 DLITIKIVEDKIKAIKKNKDFILDGFPRNICQAEALDKFLPNVKI-----INFLIDEELV 115 Query: 119 VRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNME 178 ++R+SGRRIC C ++++ K G CD+CGG+L QR DD+ E ++ R Y + Sbjct: 116 IKRLSGRRICKSCNNIFNIYTLTTKKNGICDVCGGDLYQREDDKEECLKTRLKEYKLQTK 175 Query: 179 PIIKFYQKQGIYVRIDGHGSIDEVWERI 206 P+I+FY K +D IDE+ ++I Sbjct: 176 PLIEFYSKCSRLNNVDASVKIDEIKKKI 203 >pdb|1E4V|A Chain A, Mutant G10v Of Adenylate Kinase From E. Coli, Modified In The Gly-Loop >gi|10121072|pdb|1E4V|B Chain B, Mutant G10v Of Adenylate Kinase From E. Coli, Modified In The Gly-Loop Length = 214 Score = 144 bits (359), Expect = 1e-33 Identities = 79/217 (36%), Positives = 125/217 (57%), Gaps = 11/217 (5%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 M I++ G P +GK TQA+ I E+YG+ I++GD++RA +K+ + LG + + + G L+ Sbjct: 1 MRIILLGAPVAGKGTQAQFIMEKYGIPQISTGDMLRAAVKSGSELGKQAKDIMDAGKLVT 60 Query: 61 DTIVNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 D +V L+ ++ + R F++DG+PRT Q ++ + GI +D ++ + E Sbjct: 61 DELVIALVKERIAQEDCRNGFLLDGFPRTIPQADAMK----EAGINVDYVLEFDVPDELI 116 Query: 119 VRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNME 178 V RI GRR+ + G VYHV+FNPPKV GK D+ G EL R DD+ E V KR Y + Sbjct: 117 VDRIVGRRVHAPSGRVYHVKFNPPKVEGKDDVTGEELTTRKDDQEETVRKRLVEYHQMTA 176 Query: 179 PIIKFYQKQG-----IYVRIDGHGSIDEVWERIRPLL 210 P+I +Y K+ Y ++DG + EV + +L Sbjct: 177 PLIGYYSKEAEAGNTKYAKVDGTKPVAEVRADLEKIL 213 >gi|4502013 adenylate kinase 2 isoform a; Adenylate kinase-2, mitochondrial [Homo sapiens] >gi|11423967|ref|XP_001762.1| adenylate kinase 2 isoform a [Homo sapiens] >gi|1708596|sp|P54819|KAD2_HUMAN ADENYLATE KINASE ISOENZYME 2, MITOCHONDRIAL (ATP-AMP TRANSPHOSPHORYLASE) >gi|7434597|pir||G02248 adenylate kinase (EC 2.7.4.3) 2 - human >gi|1209687|gb|AAC52061.1| (U39945) adenylate kinase 2 [Homo sapiens] >gi|1813880|gb|AAB41790.1| (U84371) adenylate kinase 2A [Homo sapiens] Length = 239 Score = 143 bits (358), Expect = 1e-33 Identities = 77/205 (37%), Positives = 119/205 (57%), Gaps = 2/205 (0%) Query: 4 LIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDTI 63 ++ GPPG+GK TQA R+ E + + ++A+GD++RA + + + LG +++ + G L+ D + Sbjct: 19 VLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEM 78 Query: 64 VNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVRR 121 V LI L + F++DG+PRT Q L++ + KLD I+ I +RR Sbjct: 79 VVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRR 138 Query: 122 ISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPII 181 I+GR I K G YH EFNPPK P K DI G LI+R DD + ++ R Y P+I Sbjct: 139 ITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTTPLI 198 Query: 182 KFYQKQGIYVRIDGHGSIDEVWERI 206 ++Y+K+GI+ ID + D V+ I Sbjct: 199 EYYRKRGIHSAIDASQTPDVVFASI 223 >gi|7524346 adenylate kinase 2 isoform a; Adenylate kinase-2, mitochondrial [Homo sapiens] >gi|11423963|ref|XP_001763.1| adenylate kinase 2 isoform b [Homo sapiens] >gi|7434595|pir||JC5893 adenylate kinase (EC 2.7.4.3) 2B - human >gi|1477653|gb|AAC13881.1| (U54645) adenylate kinase 2B [Homo sapiens] Length = 232 Score = 143 bits (358), Expect = 1e-33 Identities = 77/205 (37%), Positives = 119/205 (57%), Gaps = 2/205 (0%) Query: 4 LIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDTI 63 ++ GPPG+GK TQA R+ E + + ++A+GD++RA + + + LG +++ + G L+ D + Sbjct: 19 VLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEM 78 Query: 64 VNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVRR 121 V LI L + F++DG+PRT Q L++ + KLD I+ I +RR Sbjct: 79 VVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRR 138 Query: 122 ISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPII 181 I+GR I K G YH EFNPPK P K DI G LI+R DD + ++ R Y P+I Sbjct: 139 ITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTTPLI 198 Query: 182 KFYQKQGIYVRIDGHGSIDEVWERI 206 ++Y+K+GI+ ID + D V+ I Sbjct: 199 EYYRKRGIHSAIDASQTPDVVFASI 223 >sp|Q08479|KADA_ORYSA ADENYLATE KINASE A (ATP-AMP TRANSPHOSPHORYLASE) >gi|391877|dbj|BAA01180.1| (D10334) adenylate kinase-a [Oryza sativa] Length = 241 Score = 143 bits (357), Expect = 2e-33 Identities = 72/210 (34%), Positives = 119/210 (56%), Gaps = 2/210 (0%) Query: 3 ILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDT 62 +++ GPPG GK TQ+ I + + L ++A+GD++RA + A+TPLGI+ + + +G+L+ D Sbjct: 31 VILVGPPGCGKGTQSPLIKDEFCLCHLATGDMLRAAVAAKTPLGIKAKEAMDKGELVSDD 90 Query: 63 IVNTLIISKLRRV--RENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVR 120 +V +I +++ ++ FI+DG+PRT Q L+ L G K+D ++ I Sbjct: 91 LVVGIIDEAMKKTSCQKGFILDGFPRTVVQAQKLDEMLAKQGTKIDKVLNFAIDDAILEE 150 Query: 121 RISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPI 180 RI+GR I G YH +F PPK PG D+ G LIQR DD +++ R + + +P+ Sbjct: 151 RITGRWIHPSSGRSYHTKFAPPKTPGLDDVTGEPLIQRKDDTAAVLKSRLEAFHVQTKPV 210 Query: 181 IKFYQKQGIYVRIDGHGSIDEVWERIRPLL 210 I +Y K+GI + EV ++ L Sbjct: 211 IDYYTKKGIVANLHAEKPPKEVTVEVQKAL 240 >sp|O82514|KAD_ARATH ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|3746809|gb|AAC78478.1| (AF082882) adenylate kinase [Arabidopsis thaliana] Length = 246 Score = 142 bits (355), Expect = 3e-33 Identities = 68/210 (32%), Positives = 118/210 (55%), Gaps = 2/210 (0%) Query: 3 ILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDT 62 ++ GPPGSGK TQ+ + + Y L ++++GD++RA + ++TPLG++ + + +G+L+ D Sbjct: 36 LIFIGPPGSGKGTQSPVVKDEYCLCHLSTGDMLRAAVASKTPLGVKAKEAMEKGELVSDD 95 Query: 63 IVNTLIISKLRRVR--ENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVR 120 +V +I + + + + FI+DG+PRT Q L+ L G ++D + + + Sbjct: 96 LVVGIIDEAMNKPKCQKGFILDGFPRTVTQAEKLDEMLKRRGTEIDKVSTLLLMTQSLEE 155 Query: 121 RISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPI 180 RI+GR I G YH +F PPK PG DI G LIQR DD ++++ R + +P+ Sbjct: 156 RITGRWIHPSSGRSYHTKFAPPKTPGVDDITGEPLIQRKDDNADVLKSRLAAFHSQTQPV 215 Query: 181 IKFYQKQGIYVRIDGHGSIDEVWERIRPLL 210 I +Y K+ + I + EV ++ L Sbjct: 216 IDYYAKKAVLTNIQAEKAPQEVTSEVKKAL 245 >sp|P43412|KAD_YEREN ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|2117903|pir||S70734 adenylate kinase (EC 2.7.4.3) - Yersinia enterocolitica >gi|633690|emb|CAA87696.1| (Z47767) adenylate kinase [Yersinia enterocolitica] Length = 214 Score = 142 bits (354), Expect = 4e-33 Identities = 75/217 (34%), Positives = 125/217 (57%), Gaps = 11/217 (5%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 M I++ G PG+GK TQA+ I E+YG+ + +GD++RA +KA + LG++ + + G L+ Sbjct: 1 MRIILLGAPGAGKGTQAQFIMEKYGIPQMCTGDMLRAAVKAGSELGLKAKEIMDAGKLVT 60 Query: 61 DTIVNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 +V L+ ++ + R+ F++ G+PRT Q ++ + GIK+D ++ + E Sbjct: 61 HELVIALVKERITQDDCRDGFLLHGFPRTIPQADAMK----EAGIKVDYVLEFDVPDELI 116 Query: 119 VRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNME 178 V RI GRR+ + G VYH++FNPPKV K D+ G EL R DD+ V KR Y + Sbjct: 117 VDRIVGRRVHAASGRVYHIKFNPPKVEDKDDVTGEELTIRKDDQEATVRKRLVEYHQQTA 176 Query: 179 PIIKFYQKQG-----IYVRIDGHGSIDEVWERIRPLL 210 P++ +Y+K+ Y ++DG + EV + +L Sbjct: 177 PLVSYYRKEADAGNTQYFKLDGTRKVAEVSAELATIL 213 >dbj|BAB08805.1| (AB007649) adenylate kinase [Arabidopsis thaliana] Length = 246 Score = 142 bits (354), Expect = 4e-33 Identities = 69/210 (32%), Positives = 118/210 (55%), Gaps = 2/210 (0%) Query: 3 ILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDT 62 ++ GPPGSGK TQ+ + + Y L ++++GD++RA + ++TPLG++ + + +G+L+ D Sbjct: 36 LIFIGPPGSGKGTQSPVVKDEYCLCHLSTGDMLRAAVASKTPLGVKAKEAMEKGELVSDD 95 Query: 63 IVNTLIISKLRRVR--ENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVR 120 +V +I + + + + FI+DG+PRT Q L+ L G ++D ++ I Sbjct: 96 LVVGIIDEAMNKPKCQKGFILDGFPRTVTQAEKLDEMLKRRGTEIDKVLNFAIDDAILEE 155 Query: 121 RISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPI 180 RI+GR I G YH +F PPK PG DI G LIQR DD ++++ R + +P+ Sbjct: 156 RITGRWIHPSSGRSYHTKFAPPKTPGVDDITGEPLIQRKDDNADVLKSRLAAFHSQTQPV 215 Query: 181 IKFYQKQGIYVRIDGHGSIDEVWERIRPLL 210 I +Y K+ + I + EV ++ L Sbjct: 216 IDYYAKKAVLTNIQAEKAPQEVTSEVKKAL 245 >sp|P57556|KAD_BUCAI ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|10039147|dbj|BAB13181.1| (AP001119) adenylate kinase [Buchnera sp. APS] Length = 215 Score = 141 bits (353), Expect = 5e-33 Identities = 76/217 (35%), Positives = 129/217 (59%), Gaps = 11/217 (5%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 M I++ G PG+GK TQ + ITE+Y + I++GD++R + + +G+ ++ + G L+ Sbjct: 1 MRIILLGAPGTGKGTQGKFITEKYKIPQISTGDMLRESVVLKNKIGMIIKNIIEEGKLVS 60 Query: 61 DTIVNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 D IV LI +++++ FI+DG+PRT +Q + YL IK+D ++ I E Sbjct: 61 DEIVCHLIKNRIKKHDCINGFILDGFPRTIQQAL----YLSKKNIKIDYVLEFIIPHEYI 116 Query: 119 VRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNME 178 + RISGRRI + G +YHV+F PPK+ K D+ G LI R DD E ++KR + Y K + Sbjct: 117 LERISGRRIHIQSGRIYHVKFKPPKIKDKDDLTGQTLITRKDDTKEGIKKRLEEYKKVHD 176 Query: 179 PIIKFY---QKQG--IYVRIDGHGSIDEVWERIRPLL 210 P++++Y +K+G + +ID S + +++ +L Sbjct: 177 PLVQYYIHEKKRGNIKFFQIDAMLSFSSIRKKLETIL 213 >sp|P29410|KAD2_RAT ADENYLATE KINASE ISOENZYME 2, MITOCHONDRIAL (ATP-AMP TRANSPHOSPHORYLASE) >gi|484520|pir||JQ1944 adenylate kinase (EC 2.7.4.3) 2, mitochondrial - rat >gi|220796|dbj|BAA02378.1| (D13061) adenylate kinase 2 [Rattus norvegicus] Length = 239 Score = 141 bits (351), Expect = 9e-33 Identities = 74/205 (36%), Positives = 120/205 (58%), Gaps = 2/205 (0%) Query: 4 LIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDTI 63 ++ GPPG+GK TQA ++ E + + ++A+GD++RA + + + LG +++ + G L+ D + Sbjct: 19 VLLGPPGAGKGTQAPKLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEM 78 Query: 64 VNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVRR 121 V LI L + F++DG+PRT +Q L++ + KLD I+ I +RR Sbjct: 79 VVELIEKNLETPSCKNGFLLDGFPRTVKQAEMLDDLMDKRKEKLDSVIEFSIQDSLLIRR 138 Query: 122 ISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPII 181 I+GR I K G YH EFNPPK K DI G LI+R DD + ++ R + Y P++ Sbjct: 139 ITGRLIHPKSGRSYHEEFNPPKEAMKDDITGEPLIRRSDDNEKALKTRLEAYHTQTTPLV 198 Query: 182 KFYQKQGIYVRIDGHGSIDEVWERI 206 ++Y+K+GI+ ID + D V+ I Sbjct: 199 EYYRKRGIHCAIDASQTPDVVFASI 223 >sp|Q9WTP7|KAD3_MOUSE GTP:AMP PHOSPHOTRANSFERASE MITOCHONDRIAL (AK3) >gi|4760600|dbj|BAA77360.1| (AB020203) adenylate kinase isozyme 3 [Mus musculus] Length = 219 Score = 140 bits (349), Expect = 2e-32 Identities = 72/208 (34%), Positives = 122/208 (58%), Gaps = 7/208 (3%) Query: 4 LIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDTI 63 +I G PGSGK T + RIT+ + L +++SGD++R + T +G+ + ++ +G LIPD + Sbjct: 3 VIMGAPGSGKGTVSSRITKHFELKHLSSGDLLRQNMLQGTEIGVLAKTFIDQGKLIPDDV 62 Query: 64 VNTLIISKLRRVRE-NFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVRRI 122 + L + +L+ + + ++++DG+PRT Q L D ++D I++ + E +R+ Sbjct: 63 MTRLALHELKTLTQCSWLLDGFPRTLPQAEAL-----DKVYQIDTVINLNVPFEVIKQRL 117 Query: 123 SGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPIIK 182 + R I G VY++EFNPPK G D+ G LIQR DD+PE V KR Y EP+++ Sbjct: 118 TARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEAQTEPVLQ 177 Query: 183 FYQKQGIYVRIDGHGSIDEVWERIRPLL 210 +YQK+G+ G +++W + L Sbjct: 178 YYQKKGVLETFSG-TETNKIWPHVYSFL 204 >pdb|1E4Y|A Chain A, Mutant P9l Of Adenylate Kinase From E. Coli, Modified In The Gly-Loop >gi|10121074|pdb|1E4Y|B Chain B, Mutant P9l Of Adenylate Kinase From E. Coli, Modified In The Gly-Loop Length = 214 Score = 140 bits (349), Expect = 2e-32 Identities = 78/217 (35%), Positives = 124/217 (56%), Gaps = 11/217 (5%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 M I++ G +GK TQA+ I E+YG+ I++GD++RA +K+ + LG + + + G L+ Sbjct: 1 MRIILLGALVAGKGTQAQFIMEKYGIPQISTGDMLRAAVKSGSELGKQAKDIMDAGKLVT 60 Query: 61 DTIVNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 D +V L+ ++ + R F++DG+PRT Q ++ + GI +D ++ + E Sbjct: 61 DELVIALVKERIAQEDCRNGFLLDGFPRTIPQADAMK----EAGINVDYVLEFDVPDELI 116 Query: 119 VRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNME 178 V RI GRR+ + G VYHV+FNPPKV GK D+ G EL R DD+ E V KR Y + Sbjct: 117 VDRIVGRRVHAPSGRVYHVKFNPPKVEGKDDVTGEELTTRKDDQEETVRKRLVEYHQMTA 176 Query: 179 PIIKFYQKQG-----IYVRIDGHGSIDEVWERIRPLL 210 P+I +Y K+ Y ++DG + EV + +L Sbjct: 177 PLIGYYSKEAEAGNTKYAKVDGTKPVAEVRADLEKIL 213 >pir||B29792 adenylate kinase (EC 2.7.4.3) 2B, mitochondrial - bovine >gi|162636|gb|AAA30365.1| (M16225) adenylate kinase (EC 2.7.4.3) [Bos taurus] >gi|217607|dbj|BAA14109.1| (D90069) adenylate kinase 2B [Bos taurus] Length = 234 Score = 139 bits (347), Expect = 3e-32 Identities = 73/205 (35%), Positives = 119/205 (57%), Gaps = 2/205 (0%) Query: 4 LIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDTI 63 ++ GPPG+GK TQA ++ + + + ++A+GD++RA + + + LG +++ + G L+ D + Sbjct: 21 VLLGPPGAGKGTQAPKLAKNFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEM 80 Query: 64 VNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVRR 121 V LI L + F++DG+PRT Q L++ + KLD I+ I +RR Sbjct: 81 VLELIEKNLETPPCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRR 140 Query: 122 ISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPII 181 I+GR I + G YH EFNPPK P K DI G LI+R DD + ++ R + Y P++ Sbjct: 141 ITGRLIHPQSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNKKALKIRLEAYHTQTTPLV 200 Query: 182 KFYQKQGIYVRIDGHGSIDEVWERI 206 ++Y K+GI+ ID + D V+ I Sbjct: 201 EYYSKRGIHSAIDASQTPDVVFASI 225 >sp|P08166|KAD2_BOVIN ADENYLATE KINASE ISOENZYME 2, MITOCHONDRIAL (ATP-AMP TRANSPHOSPHORYLASE) >gi|89816|pir||JS0422 adenylate kinase (EC 2.7.4.3) 2A, mitochondrial - bovine >gi|162634|gb|AAA30364.1| (M16224) adenylate kinase (EC 2.7.4.3) [Bos taurus] >gi|217606|dbj|BAA14110.1| (D90069) adenylate kinase 2A [Bos taurus] Length = 241 Score = 139 bits (347), Expect = 3e-32 Identities = 73/205 (35%), Positives = 119/205 (57%), Gaps = 2/205 (0%) Query: 4 LIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDTI 63 ++ GPPG+GK TQA ++ + + + ++A+GD++RA + + + LG +++ + G L+ D + Sbjct: 21 VLLGPPGAGKGTQAPKLAKNFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEM 80 Query: 64 VNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVRR 121 V LI L + F++DG+PRT Q L++ + KLD I+ I +RR Sbjct: 81 VLELIEKNLETPPCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRR 140 Query: 122 ISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPII 181 I+GR I + G YH EFNPPK P K DI G LI+R DD + ++ R + Y P++ Sbjct: 141 ITGRLIHPQSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNKKALKIRLEAYHTQTTPLV 200 Query: 182 KFYQKQGIYVRIDGHGSIDEVWERI 206 ++Y K+GI+ ID + D V+ I Sbjct: 201 EYYSKRGIHSAIDASQTPDVVFASI 225 >pdb|1AK2| Adenylate Kinase Isoenzyme-2 >gi|1633467|pdb|2AK2| Adenylate Kinase Isoenzyme-2 Length = 233 Score = 139 bits (347), Expect = 3e-32 Identities = 73/205 (35%), Positives = 119/205 (57%), Gaps = 2/205 (0%) Query: 4 LIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDTI 63 ++ GPPG+GK TQA ++ + + + ++A+GD++RA + + + LG +++ + G L+ D + Sbjct: 20 VLLGPPGAGKGTQAPKLAKNFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEM 79 Query: 64 VNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVRR 121 V LI L + F++DG+PRT Q L++ + KLD I+ I +RR Sbjct: 80 VLELIEKNLETPPCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRR 139 Query: 122 ISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPII 181 I+GR I + G YH EFNPPK P K DI G LI+R DD + ++ R + Y P++ Sbjct: 140 ITGRLIHPQSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNKKALKIRLEAYHTQTTPLV 199 Query: 182 KFYQKQGIYVRIDGHGSIDEVWERI 206 ++Y K+GI+ ID + D V+ I Sbjct: 200 EYYSKRGIHSAIDASQTPDVVFASI 224 >dbj|BAA91753.1| (AK001553) unnamed protein product [Homo sapiens] >gi|7023534|dbj|BAA91996.1| (AK001951) unnamed protein product [Homo sapiens] Length = 227 Score = 139 bits (347), Expect = 3e-32 Identities = 72/221 (32%), Positives = 126/221 (56%), Gaps = 7/221 (3%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 + +I G PGSGK T + RIT + L +++SGD++R + T +G+ + ++ +G LIP Sbjct: 8 LRAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTEIGVLAKAFIDQGKLIP 67 Query: 61 DTIVNTLIISKLRRVRE-NFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESV 119 D ++ L + +L+ + + ++++DG+PRT Q L D ++D I++ + E Sbjct: 68 DDVMTRLALHELKNLTQYSWLLDGFPRTLPQAEAL-----DRAYQIDTVINLNVPFEVIK 122 Query: 120 RRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEP 179 +R++ R I G VY++EFNPPK G D+ G LIQR DD+PE V KR Y +P Sbjct: 123 QRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQTKP 182 Query: 180 IIKFYQKQGIYVRIDGHGSIDEVWERIRPLLDYIYNQENRR 220 ++++YQK+G+ G +++W + L Q +++ Sbjct: 183 VLEYYQKKGVLETFSG-TETNKIWPYVYAFLQTKVPQRSQK 222 >gi|8392883 adenylate kinase 2 [Mus musculus] >gi|6707706|sp|Q9WTP6|KAD2_MOUSE ADENYLATE KINASE ISOENZYME 2, MITOCHONDRIAL (ATP-AMP TRANSPHOSPHORYLASE) >gi|4760598|dbj|BAA77359.1| (AB020202) adenylate kinase isozyme 2 [Mus musculus] Length = 232 Score = 138 bits (345), Expect = 4e-32 Identities = 73/205 (35%), Positives = 118/205 (56%), Gaps = 2/205 (0%) Query: 4 LIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDTI 63 ++ GPPG+GK TQA ++ E + + ++A+GD++RA + + + L +++ + G L+ D + Sbjct: 19 VLLGPPGAGKGTQAPKLAENFCVCHLATGDMLRAMVASGSELRKKLKATMDAGKLVSDEM 78 Query: 64 VNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVRR 121 V LI L + F++DG+PRT Q L+ + +LD I+ I +RR Sbjct: 79 VVELIEKNLETPSCKNGFLLDGFPRTVRQAEMLDELMEKRKEELDSVIEFSIQDSLLIRR 138 Query: 122 ISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPII 181 I+GR I K G YH EFNPPK P K DI G LI+R DD + ++ R + Y P++ Sbjct: 139 ITGRLIRPKSGRFYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKTRLEAYYTQTTPLV 198 Query: 182 KFYQKQGIYVRIDGHGSIDEVWERI 206 ++Y+K+GI+ ID + D V+ I Sbjct: 199 EYYRKRGIHCAIDASQTPDIVFASI 223 >gb|AAF97187.1|AF268611_10 (AF268611) adenylate kinase [uncultured marine group II euryarchaeote 37F11] Length = 216 Score = 137 bits (342), Expect = 1e-31 Identities = 74/204 (36%), Positives = 112/204 (54%), Gaps = 8/204 (3%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 +NI++FGPPG+GK TQA+R+ + GL +++GD++RA +KA T +GIE + Y+ +G L+P Sbjct: 10 LNIVLFGPPGAGKGTQAQRMMDATGLPQVSTGDMLRAAVKAGTSVGIEAKSYMDKGALVP 69 Query: 61 DTIVNTLIISKLR--RVRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 D+++ LI +L + + DG+PRT Q L +++ + I + E Sbjct: 70 DSVIIDLIRDRLHDDDAKNGVMFDGFPRTVPQAEALSEI-----VEVSAVLAIDVPDERI 124 Query: 119 VRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNME 178 V RI GR C CG VYH FNP + G C +R DD E V R + Y Sbjct: 125 VERICGRYSCGTCGTVYHDTFNPIQ-NGICGCGSFTEKRRADDVEETVLARLEAYHTQTS 183 Query: 179 PIIKFYQKQGIYVRIDGHGSIDEV 202 P+ FY+ GI+ +DG ID + Sbjct: 184 PLADFYRAAGIFHHVDGDRDIDVI 207 >gi|7705272 adenylate kinase 3 alpha like [Homo sapiens] >gi|11130641|sp|Q9UIJ7|KAD3_HUMAN GTP:AMP PHOSPHOTRANSFERASE MITOCHONDRIAL (AK3) (AK3-ALPHA) >gi|6518533|dbj|BAA87913.1| (AB021870) adenylate kinase 3 alpha [Homo sapiens] Length = 227 Score = 137 bits (341), Expect = 1e-31 Identities = 71/221 (32%), Positives = 124/221 (55%), Gaps = 7/221 (3%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 + +I G PGSGK T + RIT + L +++ GD++R + T +G+ + ++ +G LIP Sbjct: 8 LRAVIMGAPGSGKGTVSSRITTHFELKHLSRGDLLRDNMLRGTEIGVLAQAFIDQGKLIP 67 Query: 61 DTIVNTLIISKLRRVRE-NFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESV 119 D + L + +L+ + + ++++DG+PRT Q L D ++D I++ + E Sbjct: 68 DYVTTRLALHELKNLTQYSWLLDGFPRTLPQAEAL-----DRAYQIDTVINLNVPFEVIK 122 Query: 120 RRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEP 179 +R++ R I G VY++EFNPPK G D+ G LIQR DD+PE V KR Y +P Sbjct: 123 QRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQTKP 182 Query: 180 IIKFYQKQGIYVRIDGHGSIDEVWERIRPLLDYIYNQENRR 220 ++++YQK+G+ G +++W + L Q +++ Sbjct: 183 VLEYYQKKGVLETFSG-TETNKIWPYVYAFLQTKVPQRSQK 222 >gb|AAF54578.1| (AE003689) CG6612 gene product [Drosophila melanogaster] Length = 216 Score = 137 bits (341), Expect = 1e-31 Identities = 72/213 (33%), Positives = 120/213 (55%), Gaps = 11/213 (5%) Query: 4 LIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDTI 63 +I G PGSGK T + I + +G +I++GDI+R I T LG + ++Y++ G L+PD I Sbjct: 9 VIIGAPGSGKGTISELICKNHGCVHISTGDILRQNIIKNTELGKKAKQYIAEGKLVPDAI 68 Query: 64 VNTLIISKLRRV-RENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVRRI 122 V +++++ V ++I+DG+PR Q L ++D I + + + R+ Sbjct: 69 VTKTMLARITEVGNRSYILDGFPRNIAQAEALAARE-----QIDAVITLDVPHSVIIDRV 123 Query: 123 SGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPIIK 182 R I + G VY++ F PKVPGK D+ G L+QR DD+P +V KR ++Y + M P+I Sbjct: 124 KNRWIHAPSGRVYNIGFKNPKVPGKDDVTGEPLMQREDDKPHVVAKRLELYDEVMSPVIA 183 Query: 183 FYQKQGIYVRIDGHGSIDEVWERIRPLLDYIYN 215 +Y+K+G+ G E+W P+++ N Sbjct: 184 WYEKKGLVATFKGK-QTKEIW----PMMELFLN 211 >gb|AAF47139.1| (AE003462) Adk2 gene product [Drosophila melanogaster] Length = 237 Score = 136 bits (340), Expect = 2e-31 Identities = 78/221 (35%), Positives = 125/221 (56%), Gaps = 20/221 (9%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 +N ++ GPPGSGK TQ + + ++++GD++RAEI + + LG E+++ + G L+ Sbjct: 19 INAILLGPPGSGKGTQ-------FCVCHLSTGDMLRAEISSGSKLGAELKKVMDAGKLVS 71 Query: 61 DTIVNTLIISKLRR--VRENFIMDGYPRT---PEQVIT-LENYLYDHGIKLDVAIDIYIT 114 D +V +I S L + + F++DG+PRT E+V T L+ L LD I+ I Sbjct: 72 DDLVVDMIDSNLDKPECKNGFLLDGFPRTVVQAEKVATRLDTLLDKRKTNLDAVIEFAID 131 Query: 115 KEESVRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYS 174 VRRI+GR I G YH EF PPK P D+ G LI+R DD E ++KR + Y Sbjct: 132 DSLLVRRITGRLIHQASGRSYHEEFAPPKKPMTDDVTGEPLIRRSDDNAEALKKRLEAYH 191 Query: 175 KNMEPIIKFYQKQGIYVRIDG-------HGSIDEVWERIRP 208 K +P++ +Y +G++ ++D +ID +++R RP Sbjct: 192 KQTKPLVDYYGLRGLHFKVDAAKKSSDVFSTIDSIFQRKRP 232 >sp|Q9PQP0|KAD_UREPA ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|11260823|pir||D82917 adenylate kinase UU251 [imported] - Ureaplasma urealyticum >gi|6899221|gb|AAF30660.1|AE002122_29 (AE002122) adenylate kinase [Ureaplasma urealyticum] Length = 213 Score = 136 bits (339), Expect = 2e-31 Identities = 74/214 (34%), Positives = 122/214 (56%), Gaps = 9/214 (4%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERY-LSRGDLI 59 M IL+ GPPGSGK + + +T+ L ++++G++ RA +K + L +++ +S G L+ Sbjct: 1 MKILLIGPPGSGKGSVSELLTKNNTLKHVSTGNLFRAILKEDSELARKIKEINVSGGKLV 60 Query: 60 PDTIVNTLI---ISKLRRVRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKE 116 PD I N + I +L + ++FI+DGYPRT Q + LE Y LD + I + Sbjct: 61 PDEITNQVAKSAIDELIKNEQSFILDGYPRTINQALALEQYC-----NLDYIFYLDIDHQ 115 Query: 117 ESVRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKN 176 E ++R++GR +C KC +Y++ F P+V G CD L QR DD + V R D Y K Sbjct: 116 ELMKRLTGRWMCPKCAGIYNIHFKKPQVHGLCDNDQATLYQRADDHADAVSIRLDEYDKL 175 Query: 177 MEPIIKFYQKQGIYVRIDGHGSIDEVWERIRPLL 210 P+IK Y+ +++I+ + I++V++ I L Sbjct: 176 TLPLIKHYETNPRFIKINANQPIEDVYKNINNYL 209 >sp|P10251|KAD_MYCCA ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|66941|pir||KIYMC adenylate kinase (EC 2.7.4.3) - Mycoplasma capricolum >gi|44229|emb|CAA29724.1| (X06414) adenylate kinase (AA 1-213) [Mycoplasma capricolum] Length = 213 Score = 136 bits (338), Expect = 3e-31 Identities = 67/208 (32%), Positives = 116/208 (55%), Gaps = 1/208 (0%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 MNI++ G PG GK TQA ++ + +++GD++R EI T LG++ + Y++ G +P Sbjct: 1 MNIMLLGAPGCGKGTQAEQLVNKLNFIQVSTGDLMRKEISLNTTLGLKCQEYMNAGKYVP 60 Query: 61 DTIVNTLIISKLRRVRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVR 120 D IVN ++ L+ + I DGYPRT EQ LE L + K+D I + ++ ++ Sbjct: 61 DQIVNQIVNQFLQYNNDKLIFDGYPRTLEQAKLLEKMLDLYNKKIDYVFYIDVNEQILIK 120 Query: 121 RISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPI 180 RI+ R +C C A +++E PK G CD +L++R DD + V+ R Y + P+ Sbjct: 121 RITNRLVCPLCKASFNLETRKPKQEGLCDFDNTKLVKRSDDSLDKVKIRLQTYKEQTLPL 180 Query: 181 IKFYQKQGIYVRIDGHG-SIDEVWERIR 207 I +++ ++ I S ++V+ +I+ Sbjct: 181 IDYFKTNSKFIEIKADNLSAEQVFNQIK 208 >gi|6753022 adenylate kinase 4 [Mus musculus] >gi|6707708|sp|Q9WUR9|KAD4_MOUSE ADENYLATE KINASE ISOENZYME 4, MITOCHONDRIAL (ATP-AMP TRANSPHOSPHORYLASE) >gi|4877395|dbj|BAA77760.1| (D85036) adenylate kinase 4 [Mus musculus] Length = 223 Score = 134 bits (335), Expect = 7e-31 Identities = 72/210 (34%), Positives = 120/210 (56%), Gaps = 7/210 (3%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 + +I GPPGSGK T RI + +GL +++SG ++R +K T +G ++YL +G L+P Sbjct: 6 LRAVILGPPGSGKGTVCERIAQNFGLQHLSSGHLLRENLKTGTEVGDVAKQYLEKGLLVP 65 Query: 61 DTIVNTLIISKLR-RVRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESV 119 D ++ L++S+L R +++++DG+PRT Q L+ +D+ I + I E Sbjct: 66 DHVITRLMMSELETRSAQHWLLDGFPRTLVQAEALDGIC-----DVDLVISLNIPFETLK 120 Query: 120 RRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEP 179 R+S R I G VY+++FNPP+V G DI G L+Q+ DD+PE V R Y +P Sbjct: 121 DRLSRRWIHPSSGRVYNLDFNPPQVQGIDDITGEPLVQQEDDKPEAVAARLRRYKDAAKP 180 Query: 180 IIKFYQKQGIYVRIDGHGSIDEVWERIRPL 209 +I+ Y+ +G+ + G + +W + L Sbjct: 181 VIELYKSRGVLHQFSG-TETNRIWPYVYTL 209 >gi|8392885 adenylate kinase 4 [Rattus norvegicus] >gi|6707705|sp|Q9WUS0|KAD4_RAT ADENYLATE KINASE ISOENZYME 4, MITOCHONDRIAL (ATP-AMP TRANSPHOSPHORYLASE) >gi|4877399|dbj|BAA77761.1| (D87809) adenylate kinase 4 [Rattus norvegicus] Length = 223 Score = 134 bits (334), Expect = 9e-31 Identities = 72/210 (34%), Positives = 120/210 (56%), Gaps = 7/210 (3%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 + +I GPPGSGK T RI + +GL +++SG ++R +K T +G ++YL +G L+P Sbjct: 6 LRAVILGPPGSGKGTVCERIAQNFGLQHLSSGHLLRENLKTNTEVGDVAKQYLEKGLLVP 65 Query: 61 DTIVNTLIISKLR-RVRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESV 119 D ++ L++S+L R +++++DG+PRT Q L D +D+ I + I E Sbjct: 66 DHVITRLMMSELETRSAQHWLLDGFPRTLVQAEAL-----DRICDVDLVISLNIPFETLK 120 Query: 120 RRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEP 179 R+S R I G VY+++FNPP+V G DI G L+Q+ DD+PE + R Y +P Sbjct: 121 DRLSRRWIHPSSGRVYNLDFNPPQVLGVDDITGEPLVQQEDDKPEALAARLRRYKDAAKP 180 Query: 180 IIKFYQKQGIYVRIDGHGSIDEVWERIRPL 209 +I+ Y+ +G+ + G + +W + L Sbjct: 181 VIELYKSRGVLHQFSG-TETNRIWPYVYTL 209 >gi|6978479 adenylate kinase 3 [Rattus norvegicus] >gi|266402|sp|P29411|KAD3_RAT GTP:AMP PHOSPHOTRANSFERASE MITOCHONDRIAL (AK3) >gi|484521|pir||JQ1945 nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) 3, mitochondrial - rat >gi|450312|dbj|BAA02379.1| (D13062) adenylate kinase 3 [Rattus norvegicus] Length = 227 Score = 134 bits (333), Expect = 1e-30 Identities = 69/196 (35%), Positives = 114/196 (57%), Gaps = 6/196 (3%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 + +I G PGSGK T + RIT+ + L +++SGD++R + T + + + ++ +G LIP Sbjct: 8 LRAVIMGAPGSGKGTGSSRITKHFELKHLSSGDLLRQNMLQGTEIAVLAKSFIDQGKLIP 67 Query: 61 DTIVNTLIISKLRRVRE-NFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESV 119 D + L + +L+ + + ++++DG+PRT Q L D ++D I++ + E Sbjct: 68 DDDMTRLALHELKNLTQCSWLLDGFPRTLPQAEAL-----DRVYQIDTVINLNVPFEVIK 122 Query: 120 RRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEP 179 R++ R I G VY++EFNPPK G D+ G LIQR DD+PE V KR Y EP Sbjct: 123 LRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEAQTEP 182 Query: 180 IIKFYQKQGIYVRIDG 195 ++++YQK+G+ G Sbjct: 183 VLQYYQKKGVLETFSG 198 >sp|Q9ZCS6|KAD_RICPR ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|7434606|pir||D71669 adenylate kinase (adk) RP638 - Rickettsia prowazekii >gi|3861178|emb|CAA15078.1| (AJ235272) ADENYLATE KINASE (adk) [Rickettsia prowazekii] Length = 213 Score = 133 bits (332), Expect = 1e-30 Identities = 70/213 (32%), Positives = 115/213 (53%), Gaps = 6/213 (2%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 M ++ GPPG+GK TQ ++I ++ L +IA GDI R IK T + Y+ +G LIP Sbjct: 1 MIVIFLGPPGAGKGTQGKKIAKKIDLPHIAVGDIFRTIIKTSTSEAELINNYVKQGALIP 60 Query: 61 DTIVNTLIISKL--RRVRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 + IVN +I L + + +I+DGYPR EQ E ++ IK+ I + E Sbjct: 61 NEIVNQVIKVFLLSSKYKNGYILDGYPRNLEQAKFFEAFIQKPQIKI---IYFDVADELL 117 Query: 119 VRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQ-RPDDRPEIVEKRYDIYSKNM 177 ++R+ GR C CG +Y++ F PK+ CD+C + R DD E+++KR +Y Sbjct: 118 IKRVLGRYSCKNCGKIYNIHFLQPKIEHVCDVCSSSVFDYRKDDNKEVIKKRIKVYKTET 177 Query: 178 EPIIKFYQKQGIYVRIDGHGSIDEVWERIRPLL 210 P+I +Y+ G + ++ + + E+ I+ +L Sbjct: 178 YPLIDYYKNSGNFYIVNANKNEQEIENDIQKIL 210 >pir||B82825 adenylate kinase XF0275 [imported] - Xylella fastidiosa (strain 9a5c) >gi|9105094|gb|AAF83088.1|AE003881_1 (AE003881) adenylate kinase [Xylella fastidiosa] Length = 198 Score = 133 bits (331), Expect = 2e-30 Identities = 71/208 (34%), Positives = 117/208 (56%), Gaps = 29/208 (13%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 M +++ GPPGSGK TQA ++ E + +I++GD++R+E+ A TPLG++ ++ +++GDL+ Sbjct: 12 MRLVLLGPPGSGKGTQAAQMKETLQIPHISTGDLLRSEVVAGTPLGLQAKQVMAQGDLVS 71 Query: 61 DTIVNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 D I+ ++ S+L V + FI+DGYPR Q L+ L G L+ + + + + Sbjct: 72 DAILIGMLESRLSHTDVVKGFILDGYPRNLSQAAALDGLLAKLGHPLNAVVQLEVPTDVL 131 Query: 119 VRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNME 178 V RI+GR + R DD P+ V KR +Y+ + Sbjct: 132 VERIAGR---------------------------AQAEGREDDTPDAVRKRLQVYNDSTA 164 Query: 179 PIIKFYQKQGIYVRIDGHGSIDEVWERI 206 P+I FYQ++GI +R+DG G +DEV +RI Sbjct: 165 PVIGFYQQRGILLRVDGVGRLDEVSQRI 192 >gi|8051579 adenylate kinase 3; Adenylate kinase-3, mitochondrial; GTP:AMP phosphotransferase [Homo sapiens] >gi|125157|sp|P27144|KAD4_HUMAN ADENYLATE KINASE ISOENZYME 4, MITOCHONDRIAL (ATP-AMP TRANSPHOSPHORYLASE) >gi|1070480|pir||KIHUA3 nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) 3 - human >gi|28577|emb|CAA43088.1| (X60673) nucleoside-triphosphate--adenylate kinase [Homo sapiens] Length = 223 Score = 132 bits (330), Expect = 3e-30 Identities = 72/210 (34%), Positives = 121/210 (57%), Gaps = 7/210 (3%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 + +I GPPGSGK T +RI + +GL +++SG +R IKA T +G ++Y+ + L+P Sbjct: 6 LRAVILGPPGSGKGTVCQRIAQNFGLQHLSSGHFLRENIKASTEVGEMAKQYIEKSLLVP 65 Query: 61 DTIVNTLIISKLRRVR-ENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESV 119 D ++ L++S+L R +++++DG+PRT Q L D ++D+ I + I E Sbjct: 66 DHVITRLMMSELENRRGQHWLLDGFPRTLGQAEAL-----DKICEVDLVISLNIPFETLK 120 Query: 120 RRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEP 179 R+S R I G VY+++FNPP V G D+ G L+Q+ DD+PE V R Y +P Sbjct: 121 DRLSRRWIHPPSGRVYNLDFNPPHVHGIDDVTGEPLVQQEDDKPEAVAARLRQYKDVAKP 180 Query: 180 IIKFYQKQGIYVRIDGHGSIDEVWERIRPL 209 +I+ Y+ +G+ + G +++W + L Sbjct: 181 VIELYKSRGVLHQFSG-TETNKIWPYVYTL 209 >gi|11421812 adenylate kinase 3 [Homo sapiens] Length = 284 Score = 132 bits (330), Expect = 3e-30 Identities = 72/210 (34%), Positives = 121/210 (57%), Gaps = 7/210 (3%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 + +I GPPGSGK T +RI + +GL +++SG +R IKA T +G ++Y+ + L+P Sbjct: 67 LRAVILGPPGSGKGTVCQRIAQNFGLQHLSSGHFLRENIKASTEVGEMAKQYIEKSLLVP 126 Query: 61 DTIVNTLIISKLRRVR-ENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESV 119 D ++ L++S+L R +++++DG+PRT Q L D ++D+ I + I E Sbjct: 127 DHVITRLMMSELENRRGQHWLLDGFPRTLGQAEAL-----DKICEVDLVISLNIPFETLK 181 Query: 120 RRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEP 179 R+S R I G VY+++FNPP V G D+ G L+Q+ DD+PE V R Y +P Sbjct: 182 DRLSRRWIHPPSGRVYNLDFNPPHVHGIDDVTGEPLVQQEDDKPEAVAARLRQYKDVAKP 241 Query: 180 IIKFYQKQGIYVRIDGHGSIDEVWERIRPL 209 +I+ Y+ +G+ + G +++W + L Sbjct: 242 VIELYKSRGVLHQFSG-TETNKIWPYVYTL 270 >dbj|BAA77363.1| (AB020239) adenylate kinase 3 [Mus musculus] Length = 223 Score = 132 bits (329), Expect = 3e-30 Identities = 72/210 (34%), Positives = 119/210 (56%), Gaps = 7/210 (3%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 + +I GPPGSGK T RI + +GL +++SG ++R +K T +G ++YL +G L+P Sbjct: 6 LRAVILGPPGSGKGTVCERIAQNFGLQHLSSGHLLRENLKTGTEVGDVAKQYLEKGLLVP 65 Query: 61 DTIVNTLIISKLR-RVRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESV 119 D + L++S+L R +++++DG+PRT Q L+ +D+ I + I E Sbjct: 66 DHAITRLMMSELETRSAQHWLLDGFPRTLVQAEALDGIC-----DVDLVISLNIPFETLK 120 Query: 120 RRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEP 179 R+S R I G VY+++FNPP+V G DI G L+Q+ DD+PE V R Y +P Sbjct: 121 DRLSRRWIHPSSGRVYNLDFNPPQVQGIDDITGEPLVQQEDDKPEAVAARLRRYKDAAKP 180 Query: 180 IIKFYQKQGIYVRIDGHGSIDEVWERIRPL 209 +I+ Y+ +G+ + G + +W + L Sbjct: 181 VIELYKNRGMLHQFSG-TETNRIWPYVYTL 209 >sp|Q59591|KAD_NEIAN ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|1354897|gb|AAB49184.1| (U57713) adenylate kinase [Neisseria animalis] Length = 174 Score = 132 bits (328), Expect = 4e-30 Identities = 65/169 (38%), Positives = 102/169 (59%), Gaps = 6/169 (3%) Query: 20 ITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDTIVNTLIISKLRR--VRE 77 IT +G+ I++GD++RA IKA TPLG+E ++ + G L+ D I+ ++ ++ + + Sbjct: 2 ITAAFGIPQISTGDMLRAAIKAGTPLGLEAKKIIDEGGLVRDDIIIGMVKERIAQDDCKN 61 Query: 78 NFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVRRISGRRICSKCGAVYHV 137 F+ DG+PRT Q + + G+ LD ++I + V R+SGRR+ G YH+ Sbjct: 62 GFLFDGFPRTLAQA----EAMVEAGVDLDAVVEIDVPDSVIVDRMSGRRVHLASGRTYHI 117 Query: 138 EFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPIIKFYQK 186 +NPPKV GK D+ G +LIQR DD+ E V+KR D+Y E ++ FY K Sbjct: 118 AYNPPKVEGKDDVTGEDLIQRDDDKEETVKKRLDVYHGQTEVLVGFYSK 166 >sp|Q59596|KAD_NEIFL ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|1354901|gb|AAB49186.1| (U57711) adenylate kinase [Neisseria flavescens] Length = 174 Score = 131 bits (325), Expect = 1e-29 Identities = 65/169 (38%), Positives = 102/169 (59%), Gaps = 6/169 (3%) Query: 20 ITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDTIVNTLIISKLRR--VRE 77 IT +G+ I++GD++RA IKA TPLG+E ++ + G L+ D I+ ++ ++ + + Sbjct: 2 ITAAFGIPQISTGDMLRAAIKAGTPLGLEAKKIIDEGGLVRDDIIIGMVKERIAQDDCKN 61 Query: 78 NFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVRRISGRRICSKCGAVYHV 137 F+ DG+PRT Q + + G+ LD ++I + V R+SGRR+ G YHV Sbjct: 62 GFLFDGFPRTLAQA----EAIVEAGVDLDAVVEIDVPDSVIVDRMSGRRVHLASGRTYHV 117 Query: 138 EFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPIIKFYQK 186 +NPPKV GK D+ G +LIQR DD+ E V+KR +Y + E ++ FY K Sbjct: 118 TYNPPKVEGKDDVTGEDLIQRDDDKEETVKKRLAVYHEQTEVLVDFYSK 166 >sp|Q59615|KAD_NEILA ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|2497484|sp|Q59628|KAD_NEIPH ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|1354903|gb|AAB49187.1| (U57709) adenylate kinase [Neisseria lactamica] >gi|1354907|gb|AAB49189.1| (U57712) adenylate kinase [Neisseria pharyngis var. flava] Length = 174 Score = 131 bits (325), Expect = 1e-29 Identities = 65/169 (38%), Positives = 102/169 (59%), Gaps = 6/169 (3%) Query: 20 ITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDTIVNTLIISKLRR--VRE 77 IT +G+ I++GD++RA IKA TPLG+E ++ + G L+ D I+ ++ ++ + + Sbjct: 2 ITAAFGIPQISTGDMLRAAIKAGTPLGLEAKKIIDEGGLVRDDIIIGMVKERIAQDDCKN 61 Query: 78 NFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVRRISGRRICSKCGAVYHV 137 F+ DG+PRT Q + + G+ LD ++I + V R+SGRR+ G YHV Sbjct: 62 GFLFDGFPRTLAQA----EAMVEAGVDLDAVVEIDVPDSVIVDRMSGRRVHLASGRTYHV 117 Query: 138 EFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPIIKFYQK 186 +NPPKV GK D+ G +LIQR DD+ E V+KR +Y + E ++ FY K Sbjct: 118 TYNPPKVEGKDDVTGEDLIQRDDDKEETVKKRLAVYHEQTEVLVDFYSK 166 >emb|CAB82091.1| (AL161803) adenylate kinase (fragment) [Streptomyces coelicolor A3(2)] Length = 157 Score = 131 bits (325), Expect = 1e-29 Identities = 61/157 (38%), Positives = 98/157 (61%), Gaps = 3/157 (1%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 M I++ GPPG+GK TQA R+ E + +I++GD+ RA I +T LG + Y++ G+L+P Sbjct: 1 MRIVLVGPPGAGKGTQATRLAETLHIPHISTGDLFRANISQQTELGKLAKSYMNAGNLVP 60 Query: 61 DTIVNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 D + + ++ + F++DG+PR Q L+ L G+KLD +D+ ++E Sbjct: 61 DEVTIAMAKDRMEQPDAEGGFLLDGFPRNVSQAEALDELLETEGMKLDAVLDLEAPEDEV 120 Query: 119 VRRISGRRIC-SKCGAVYHVEFNPPKVPGKCDICGGE 154 V+RI+GRR+C ++ V+HV + PPK G CD+CGGE Sbjct: 121 VKRIAGRRVCRNEPKHVFHVTYTPPKKEGVCDVCGGE 157 >dbj|BAA94761.1| (AB041773) adenylate kinase [Oryza sativa] Length = 209 Score = 129 bits (322), Expect = 2e-29 Identities = 64/179 (35%), Positives = 105/179 (57%), Gaps = 2/179 (1%) Query: 3 ILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDT 62 +++ GPPG GK TQ+ I + + L ++A+GD++RA + A+TPLGI+ + + +G+L+ D Sbjct: 31 VILVGPPGCGKGTQSPLIKDEFCLCHLATGDMLRAAVAAKTPLGIKAKEAMDKGELVSDD 90 Query: 63 IVNTLIISKLRRV--RENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVR 120 +V +I +++ ++ FI+DG+PRT Q L+ L G K+D ++ I Sbjct: 91 LVVGIIDEAMKKTSCQKGFILDGFPRTVVQAQKLDEMLAKQGTKIDKVLNFAIDDAILEE 150 Query: 121 RISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEP 179 RI+GR I G YH +F PPK PG D+ G LIQR DD +++ R + + +P Sbjct: 151 RITGRWIHPSSGRSYHTKFAPPKTPGLDDVTGEPLIQRKDDTAAVLKSRLEAFHVQTKP 209 >sp|Q59594|KAD_NEICI ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|1354899|gb|AAB49185.1| (U57710) adenylate kinase [Neisseria cinerea] Length = 174 Score = 128 bits (318), Expect = 6e-29 Identities = 64/169 (37%), Positives = 101/169 (58%), Gaps = 6/169 (3%) Query: 20 ITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDTIVNTLIISKLRR--VRE 77 IT + + I++GD++RA IKA TPLG+E ++ + G L+ D I+ ++ ++ + + Sbjct: 2 ITAAFDIPQISTGDMLRAAIKAGTPLGLEAKKIIDEGGLVRDDIIIGMVKERIAQDDCKN 61 Query: 78 NFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVRRISGRRICSKCGAVYHV 137 F+ DG+PRT Q + + G+ LD ++I + V R+SGRR+ G YHV Sbjct: 62 GFLFDGFPRTLAQA----EAMVEAGVDLDAVVEIDVPDSVIVDRMSGRRVHLASGRTYHV 117 Query: 138 EFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPIIKFYQK 186 +NPPKV GK D+ G +LIQR DD+ E V+KR +Y + E ++ FY K Sbjct: 118 TYNPPKVEGKDDVTGEDLIQRDDDKEETVKKRLAVYHEQTEVLVDFYSK 166 >sp|P49983|KADH_TRIVA ADENYLATE KINASE PRECURSOR (ATP-AMP TRANSPHOSPHORYLASE) (AK) >gi|463923|gb|AAC46483.1| (U07203) adenylate kinase proprotein [Trichomonas vaginalis] >gi|1092412|prf||2023338A adenylate kinase [Trichomonas vaginalis] Length = 229 Score = 127 bits (317), Expect = 8e-29 Identities = 75/212 (35%), Positives = 115/212 (53%), Gaps = 5/212 (2%) Query: 3 ILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDT 62 ++ FGPPG GK TQA+ + + + L I++GD +RAEI+ +TPLG ++ + G L+ D Sbjct: 18 VVFFGPPGVGKGTQAKLLEKEFNLYQISTGDALRAEIRGQTPLGKRVKGIIESGGLVDDD 77 Query: 63 IVNTLIISKLRRVREN--FIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVR 120 + ++ + +++ +N +I DG PRT QV L+ L G L + + + +E Sbjct: 78 TIMDILQACMQKNTDNNGYIFDGIPRTIGQVEKLDALLAKMGTPLTHVLYLSVNIDELRE 137 Query: 121 RISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPI 180 R+ GR G VYH NPPK P DI G LI R DD PE+ +R + Y +P Sbjct: 138 RVCGRLFHPGSGRVYHKVTNPPKKPMTDDITGEPLIIRKDDTPEVFNQRMNQYFGTFQPC 197 Query: 181 IKFYQKQGIY--VRIDGHGSIDEVWERIRPLL 210 I +Y K+GI +DG ID V +++ L Sbjct: 198 IDYYSKKGILQTFPVDGQ-PIDVVHKKLHAAL 228 >sp|Q9Z8U0|KAD_CHLPN ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|7434607|pir||H72100 adenylate kinase CP0518 [imported] - Chlamydophila pneumoniae (strains CWL029 and AR39) >gi|4376519|gb|AAD18397.1| (AE001610) Adenylate Kinase [Chlamydophila pneumoniae CWL029] >gi|4760698|dbj|BAA77386.1| (AB022016) adenylate kinase [Chlamydophila pneumoniae] >gi|7189434|gb|AAF38344.1| (AE002211) adenylate kinase [Chlamydophila pneumoniae AR39] >gi|8978617|dbj|BAA98454.1| (AP002545) adenylate kinase [Chlamydophila pneumoniae J138] Length = 213 Score = 127 bits (317), Expect = 8e-29 Identities = 70/205 (34%), Positives = 115/205 (55%), Gaps = 7/205 (3%) Query: 4 LIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDTI 63 +I GPPGSGK TQ++ + R GL +I++GD++RA I+ TP G++ + YL +G +P Sbjct: 8 IIMGPPGSGKGTQSQYLANRIGLPHISTGDLLRAIIREGTPNGLKAKAYLDKGAFVPSDF 67 Query: 64 VNTLIISKL--RRVRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVRR 121 V ++ KL + + I+DG+PRT +Q L+++L D V I + I+++E ++R Sbjct: 68 VWEILKEKLQSQACSKGCIIDGFPRTLDQAHLLDSFLMDVHSNYTV-IFLEISEDEILKR 126 Query: 122 ISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPII 181 + R +C C +Y N + +C C LI+R DD PEI+++R Y + P+I Sbjct: 127 VCSRFLCPSCSRIY----NTSQGHTECPDCHVPLIRRSDDTPEIIKERLTKYQERTAPVI 182 Query: 182 KFYQKQGIYVRIDGHGSIDEVWERI 206 +Y G R+ D V+E I Sbjct: 183 AYYDSLGKLCRVSSENKEDLVFEDI 207 >sp|Q59627|KAD_NEIPO ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|1354905|gb|AAB49188.1| (U57708) adenylate kinase [Neisseria polysaccharea] Length = 174 Score = 127 bits (315), Expect = 1e-28 Identities = 64/169 (37%), Positives = 101/169 (58%), Gaps = 6/169 (3%) Query: 20 ITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDTIVNTLIISKLRR--VRE 77 IT +G+ I++GD++RA IKA T LG+E ++ + G L+ D I+ ++ ++ + + Sbjct: 2 ITAAFGIPQISTGDMLRAAIKAGTLLGLEAKKIIDEGGLVRDDIIIGMVKERIAQDDCKN 61 Query: 78 NFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVRRISGRRICSKCGAVYHV 137 F+ DG+PRT Q + + G+ LD ++I + V R+SGRR+ G YHV Sbjct: 62 GFLFDGFPRTLAQA----EAMVEAGVDLDAVVEIDVPDSVIVDRMSGRRVHLASGRTYHV 117 Query: 138 EFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPIIKFYQK 186 +NPPKV GK D+ G +LIQR DD+ E V+KR +Y + E ++ FY K Sbjct: 118 TYNPPKVEGKDDVTGEDLIQRDDDKEETVKKRLAVYHEQTEVLVDFYSK 166 >sp|Q9XD15|KAD_LEPIN ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) Length = 187 Score = 127 bits (315), Expect = 1e-28 Identities = 68/208 (32%), Positives = 113/208 (53%), Gaps = 29/208 (13%) Query: 2 NILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPD 61 NI+ GPPG+GK TQA+ + ER + I++GDI+R +K +T +GIE +RY+ GDL+PD Sbjct: 3 NIIFMGPPGAGKGTQAKILCERLSIPQISTGDILREAVKNQTAMGIEAKRYMDAGDLVPD 62 Query: 62 TIVNTLIISKLRRV--RENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESV 119 ++V +I ++R + F++DG+PRT EQ L+ L + G +D AI++ + E + Sbjct: 63 SVVIGIIKDRIREADCKNGFLLDGFPRTVEQAEALDTLLKNEGKSIDKAINLQVPDAELL 122 Query: 120 RRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEP 179 +R+ GR E+ R DD ++ R D Y+K P Sbjct: 123 KRLLGR---------------------------AEIEGRADDNEVTIKNRLDNYNKKTLP 155 Query: 180 IIKFYQKQGIYVRIDGHGSIDEVWERIR 207 ++ FY + +++G GS++EV I+ Sbjct: 156 LLDFYATRKKLSQVNGVGSLEEVTSLIQ 183 >sp|P43188|KADC_MAIZE ADENYLATE KINASE, CHLOROPLAST (ATP-AMP TRANSPHOSPHORYLASE) >gi|629863|pir||S45634 adenylate kinase (EC 2.7.4.3), chloroplast - maize >gi|3114421|pdb|1ZAK|A Chain A, Adenylate Kinase From Maize In Complex With The Inhibitor P1,P5-Bis(Adenosine-5'-)pentaphosphate (Ap5a) >gi|3114422|pdb|1ZAK|B Chain B, Adenylate Kinase From Maize In Complex With The Inhibitor P1,P5-Bis(Adenosine-5'-)pentaphosphate (Ap5a) Length = 222 Score = 126 bits (314), Expect = 2e-28 Identities = 74/221 (33%), Positives = 126/221 (56%), Gaps = 13/221 (5%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 + ++I G P SGK TQ I +Y L +I++GD++RAEI A + G + ++ +G L+P Sbjct: 6 LKVMISGAPASGKGTQCELIKTKYQLAHISAGDLLRAEIAAGSENGKRAKEFMEKGQLVP 65 Query: 61 DTIVNTLIISKLRR--VREN-FIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEE 117 D IV ++ +LR+ +EN +++DGYPR+ Q + LE I+ D I + + E Sbjct: 66 DEIVVNMVKERLRQPDAQENGWLLDGYPRSYSQAMALETL----EIRPDTFILLDVPDEL 121 Query: 118 SVRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNM 177 V R+ GRR+ G +YH++++PP + + L QR DD E V+ R + Y +N+ Sbjct: 122 LVERVVGRRLDPVTGKIYHLKYSPP----ENEEIASRLTQRFDDTEEKVKLRLETYYQNI 177 Query: 178 EPIIKFYQKQGIYVRIDGHGSIDEVWERIRPLLDYIYNQEN 218 E ++ Y + I V++ G ++D V+ +I LL I ++N Sbjct: 178 ESLLSTY--ENIIVKVQGDATVDAVFAKIDELLGSILEKKN 216 >pir||T02575 adenylate kinase homolog T16B24.9 - Arabidopsis thaliana >gi|3402678|gb|AAC28981.1| (AC004697) putative adenylate kinase [Arabidopsis thaliana] Length = 295 Score = 123 bits (307), Expect = 1e-27 Identities = 69/220 (31%), Positives = 120/220 (54%), Gaps = 24/220 (10%) Query: 4 LIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDTI 63 + G PG GK T A R++ G+ +IA+GD++R E+ + L +++ ++ G L+PD Sbjct: 68 VFLGCPGVGKGTYASRLSSLLGVPHIATGDLVREELSSSGLLSSQLKELVNHGKLVPDEF 127 Query: 64 VNTLIISKLRRVRE----NFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESV 119 + +L+ +L+ ++ +I+DG+PRT Q LE +D+ I++ + +E + Sbjct: 128 IISLLSKRLQAGKDKGESGYILDGFPRTVTQAEILEGV-----TNIDLVINLKLREEALL 182 Query: 120 RRISGRRICSKCGAVYHVE-------------FNPPKVPGKCDICGGELIQRPDDRPEIV 166 + GRRICS+CG Y+V + PP +P C +LI R DD E+V Sbjct: 183 AKCLGRRICSECGGNYNVACIDIKGDDDTPRMYMPPLLPP--PNCESKLISRADDTEEVV 240 Query: 167 EKRYDIYSKNMEPIIKFYQKQGIYVRIDGHGSIDEVWERI 206 ++R IY+K +P+ +FY+K+G + + G I E W R+ Sbjct: 241 KERLRIYNKMTQPVEEFYKKRGKLLEFELPGGIPESWARL 280 >dbj|BAB11331.1| (AB016886) contains similarity to adenylate kinase~gene_id:MCA23.18 [Arabidopsis thaliana] Length = 283 Score = 123 bits (305), Expect = 2e-27 Identities = 67/221 (30%), Positives = 125/221 (56%), Gaps = 13/221 (5%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 + I+I G P SGK TQ IT +YGL +I++GD++RAEI + + G + ++ +G L+P Sbjct: 65 LKIMISGAPASGKGTQCELITHKYGLVHISAGDLLRAEIASGSENGRRAKEHMEKGQLVP 124 Query: 61 DTIVNTLIISKLRRV---RENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEE 117 D IV ++ +L + ++ +++DGYPR+ Q L+ + G + D+ I + + +E Sbjct: 125 DEIVVMMVKDRLSQTDSEQKGWLLDGYPRSASQATALKGF----GFQPDLFIVLEVPEEI 180 Query: 118 SVRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNM 177 + R+ GRR+ G +YH++++PP+ + L QR DD E + R +++N+ Sbjct: 181 LIERVVGRRLDPVTGKIYHLKYSPPET----EEIAVRLTQRFDDTEEKAKLRLKTHNQNV 236 Query: 178 EPIIKFYQKQGIYVRIDGHGSIDEVWERIRPLLDYIYNQEN 218 ++ Y I ++I+G+ S +EV+ +I L + + N Sbjct: 237 SDVLSMY--DDITIKIEGNRSKEEVFAQIDSSLSELLQERN 275 >gb|AAD40604.1|AF115283_23 (AF115283) adenylate kinase [Leptospira interrogans] Length = 181 Score = 122 bits (303), Expect = 4e-27 Identities = 66/203 (32%), Positives = 110/203 (53%), Gaps = 29/203 (14%) Query: 7 GPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDTIVNT 66 GPPG+GK TQA+ + ER + I++GDI+R +K +T +GIE +RY+ GDL+PD++V Sbjct: 2 GPPGAGKGTQAKILCERLSIPQISTGDILREAVKNQTAMGIEAKRYMDAGDLVPDSVVIG 61 Query: 67 LIISKLRRV--RENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVRRISG 124 +I ++R + F++DG+PRT EQ L+ L + G +D AI++ + E ++R+ G Sbjct: 62 IIKDRIREADCKNGFLLDGFPRTVEQAEALDTLLKNEGKSIDKAINLQVPDAELLKRLLG 121 Query: 125 RRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPIIKFY 184 R E+ R DD ++ R D Y+K P++ FY Sbjct: 122 R---------------------------AEIEGRADDNEVTIKNRLDNYNKKTLPLLDFY 154 Query: 185 QKQGIYVRIDGHGSIDEVWERIR 207 + +++G GS++EV I+ Sbjct: 155 ATRKKLSQVNGVGSLEEVTSLIQ 177 >sp|Q09629|KADY_CAEEL PROBABLE ADENYLATE KINASE ISOENZYME ZK673.2 (ATP-AMP TRANSPHOSPHORYLASE) >gi|7511272|pir||T27960 hypothetical protein ZK673.2 - Caenorhabditis elegans >gi|3881762|emb|CAA88479.1| (Z48585) contains similarity to Pfam domain: PF00406 (Adenylate kinase), Score=179.5, E-value=1.7e-50, N=1~cDNA EST EMBL:Z14633 comes from this gene~cDNA EST yk116g6.5 comes from this gene~cDNA EST yk116g6.3 comes from this gene~cDNA EST yk505a4.3 come> Length = 222 Score = 122 bits (302), Expect = 5e-27 Identities = 60/199 (30%), Positives = 109/199 (54%), Gaps = 8/199 (4%) Query: 3 ILIFGPPGSGKSTQARRITERY---GLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLI 59 +L+ G GSGK T AR + + G Y A+GD IR I T G+ + +L++G+ + Sbjct: 4 VLLSGAAGSGKGTIARMLVREFEPLGFNYFAAGDFIRDHIARGTEFGVRAQSFLNKGEHV 63 Query: 60 PDTIVNTLIISKLRRVRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESV 119 PD+I+N I++++ + ++DGYPR Q+ +E L++ +++ + ++ + Sbjct: 64 PDSILNGAILAEMLKAGPRVVLDGYPRNMSQLKMVEEQA-----PLNLIVELKVPRKVLI 118 Query: 120 RRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEP 179 R+S + + G Y++E NPPK GK DI G L +R D+ E+ +R ++Y K Sbjct: 119 DRLSKQLVHPASGRAYNLEVNPPKEEGKDDITGEPLFKRSTDQLEVARRRLEVYDKTENK 178 Query: 180 IIKFYQKQGIYVRIDGHGS 198 ++ +Y+KQ + + G S Sbjct: 179 VLDYYKKQNKCITMSGESS 197 >gi|10954728 adk gene homolog [Agrobacterium rhizogenes] >gi|8918728|dbj|BAA97793.1| (AB039932) adk gene homolog [Agrobacterium rhizogenes] >gi|10567392|dbj|BAB16201.1| (AP002086) adk gene homolog [Agrobacterium rhizogenes] Length = 194 Score = 121 bits (301), Expect = 6e-27 Identities = 71/213 (33%), Positives = 112/213 (52%), Gaps = 28/213 (13%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 M +++ GPPGSGK TQA+RI E+ G+ ++++GDI+RAE+KA TPLG+ + ++ G L+ Sbjct: 1 MRLILMGPPGSGKGTQAKRICEKLGIPHLSTGDILRAEVKAGTPLGLAVAATMAAGGLVS 60 Query: 61 DTIVNTLIISKLR--RVRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 D V+ ++ S++ + F++DG+PRT Q L+ L +H L I++ + +EE Sbjct: 61 DDTVSAIVASRIAGPEAQRGFVLDGFPRTISQAAALDQSLGEH--SLTAVIELVVPEEEL 118 Query: 119 VRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNME 178 RI RR GA QR DD +E R Y Sbjct: 119 YDRIC-RRAAESAGA-----------------------QRADDNAATLELRLKAYRAETL 154 Query: 179 PIIKFYQKQGIYVRIDGHGSIDEVWERIRPLLD 211 + +FY+ + Y +IDG + +EV RI LL+ Sbjct: 155 SVSEFYKGRSPYFQIDGLAAPEEVTARILELLE 187 >sp|P47417|KAD_MYCGE ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|1361442|pir||I64218 adenylate kinase (EC 2.7.4.3) - Mycoplasma genitalium >gi|3844765|gb|AAC71389.1| (U39696) adenylate kinase (adk) [Mycoplasma genitalium] Length = 214 Score = 120 bits (299), Expect = 1e-26 Identities = 63/210 (30%), Positives = 116/210 (55%), Gaps = 8/210 (3%) Query: 4 LIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDTI 63 +I GPPG+GK T + +++ L +IASGD+ R IK ++ +G ++ +S+G + D Sbjct: 9 IILGPPGAGKGTVCKLLSKTTKLVHIASGDLFREAIKNQSVIGRKIAAIISQGGYVDDAT 68 Query: 64 VNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITK-EESVR 120 N L+ + + FI+DGYPRT Q+ L L +D+ ++ ++ + + Sbjct: 69 TNQLVYEYITTNPLPNGFILDGYPRTENQLDFLNIKL-----TIDMVFELVVSDLNKLIT 123 Query: 121 RISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPI 180 RI R IC+ C +VY++ F P V CD C +L++R DD +V+ R ++Y + ++PI Sbjct: 124 RIDNRVICNNCNSVYNLLFQKPLVENSCDQCSAKLVKRSDDNKAVVKARMELYQQTIQPI 183 Query: 181 IKFYQKQGIYVRIDGHGSIDEVWERIRPLL 210 ++ + + V+ID ++E + I+ + Sbjct: 184 HTYFFNKQLLVQIDCFLPLEEQLKTIKQFI 213 >sp|O84130|KAD_CHLTR ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|7434610|pir||D71554 probable adenylate cyclase - Chlamydia trachomatis (serotype D, strain UW3/Cx) >gi|3328527|gb|AAC67719.1| (AE001286) adenylate kinase [Chlamydia trachomatis] Length = 245 Score = 120 bits (297), Expect = 2e-26 Identities = 68/219 (31%), Positives = 114/219 (52%), Gaps = 20/219 (9%) Query: 3 ILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDT 62 ++I G PGSGK TQ++ + + L +I+SGD++R + TPL E++ YL +G L+PDT Sbjct: 8 LIIMGAPGSGKGTQSKLLASQLSLLHISSGDLLRDAVSKDTPLSQEIKSYLDQGKLLPDT 67 Query: 63 IVNTLI---------------ISKLRRVRENFIMDGYPRTPEQVITLENYLYDHGIKLDV 107 +V L+ +S L R + I+DG+PRT Q L +L + V Sbjct: 68 LVWKLVHEKLDEFQQDTLLRRLSFLSRSENSAILDGFPRTVTQAKLLHEFLSSYFPNYKV 127 Query: 108 AIDIYITKEESVRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVE 167 + + I+ EE + R++ R IC C +Y N + C C ELI+R DD E++ Sbjct: 128 IL-LDISDEEVLNRLTSRYICPACQGIY----NEQQGFSSCPKCSVELIRRSDDTLEVIL 182 Query: 168 KRYDIYSKNMEPIIKFYQKQGIYVRIDGHGSIDEVWERI 206 R Y + +P++ +Y ++ + ID + +V++ I Sbjct: 183 DRIQTYKQETQPVLDYYTEKQKLITIDANAPTQQVFQSI 221 >sp|Q9PKR0|KAD_CHLMU ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|11260850|pir||B81706 adenylate kinase TC0404 [imported] - Chlamydia muridarum (strain Nigg) >gi|7190446|gb|AAF39261.1| (AE002307) adenylate kinase [Chlamydia muridarum] Length = 253 Score = 119 bits (295), Expect = 3e-26 Identities = 67/219 (30%), Positives = 112/219 (50%), Gaps = 20/219 (9%) Query: 3 ILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDT 62 ++I G PGSGK TQ++ + + L +I+SGD++R + TPLG E++ YL +G L+PD Sbjct: 8 LIIMGAPGSGKGTQSKLLASQLSLQHISSGDLLRNAVSQNTPLGQEIKSYLDQGKLLPDQ 67 Query: 63 IVNTLI---------------ISKLRRVRENFIMDGYPRTPEQVITLENYLYDHGIKLDV 107 +V L+ +S L R I+DG+PRT Q L +L + + Sbjct: 68 LVWKLVHEKLDELQQDTLLRKLSFLSRSENGAILDGFPRTVAQAKLLNEFLCSYFPDYKI 127 Query: 108 AIDIYITKEESVRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVE 167 + + I+ EE + R++ R IC C +Y N + +C C EL +R DD PE++ Sbjct: 128 IL-LDISDEEVLNRLTSRYICPSCQGIY----NKQQGFSRCPKCLVELTRRSDDTPEVIL 182 Query: 168 KRYDIYSKNMEPIIKFYQKQGIYVRIDGHGSIDEVWERI 206 R Y + +P++ +Y + ID + +V++ I Sbjct: 183 DRIQTYKQETQPVLDYYAALQRLITIDANAPTQQVFKNI 221 >sp|O52352|KAD_MYCGA ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|2766523|gb|AAB95407.1| (AF036708) adenylate kinase [Mycoplasma gallisepticum] Length = 214 Score = 118 bits (294), Expect = 4e-26 Identities = 65/218 (29%), Positives = 121/218 (54%), Gaps = 13/218 (5%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKA-RTPLGIEMERYLSRGDLI 59 + ++ G PG+GK T + + E++G +I+SGD+ R K +T L E++ Y++ G + Sbjct: 2 IRLIFLGAPGTGKGTISSYLKEQHGFFHISSGDLFRFYAKEEKTALAEEIKSYINNGLYV 61 Query: 60 PDTIVNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYL-YDHGIKLDVAIDIYITKE 116 PD + N + + ++ I DGYPRT Q ++ + + H I L + Sbjct: 62 PDELTNRTVADFYHKNQSQDKIIFDGYPRTLNQCEYIDEIIKFTHVILLQPT-----DWD 116 Query: 117 ESVRRISGRRICSKCGAVYH---VEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIY 173 + R+S RR C +C +Y+ V+F P KV CD+C ELI R DD P +V R ++Y Sbjct: 117 MIINRLSSRRSCPQCKRIYNINSVDFKP-KVANLCDLCKVELIHRKDDDPSVVSTRINVY 175 Query: 174 SKNMEPIIKFYQKQGIYVRIDGHGSIDEVWERIRPLLD 211 ++ +P+I++Y+K+ + +D + S +E+++ + +++ Sbjct: 176 NEQTKPVIEYYKKKNLLHLVDANKSFEELYKLVLEIVN 213 >sp|O53796|KAD_MYCTU ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|7434593|pir||H70822 probable adenylate kinase - Mycobacterium tuberculosis (strain H37RV) >gi|2911007|emb|CAA17500.1| (AL021958) adk [Mycobacterium tuberculosis] >gi|4191722|gb|AAD09879.1| (U77912) adenylate kinase [Mycobacterium bovis] Length = 181 Score = 115 bits (285), Expect = 5e-25 Identities = 62/207 (29%), Positives = 103/207 (48%), Gaps = 35/207 (16%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 M +L+ GPPG+GK TQA ++ E+ G+ I++G++ R I+ T LG+E +RYL GDL+P Sbjct: 1 MRVLLLGPPGAGKGTQAVKLAEKLGIPQISTGELFRRNIEEGTKLGVEAKRYLDAGDLVP 60 Query: 61 DTIVNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 + N L+ +L FI+DGYPR+ EQ L L G +D ++ +++E Sbjct: 61 SDLTNELVDDRLNNPDAANGFILDGYPRSVEQAKALHEMLERRGTDIDAVLEFRVSEEVL 120 Query: 119 VRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNME 178 + R+ GR R DD +++ R +Y Sbjct: 121 LERLKGR-------------------------------GRADDTDDVILNRMKVYRDETA 149 Query: 179 PIIKFYQKQGIYVRIDGHGSIDEVWER 205 P++++Y+ Q +D G++DEV+ R Sbjct: 150 PLLEYYRDQ--LKTVDAVGTMDEVFAR 174 >gb|AAC46846.1| (U19901) adenylate kinase [Giardia intestinalis] Length = 247 Score = 114 bits (283), Expect = 8e-25 Identities = 60/203 (29%), Positives = 119/203 (58%), Gaps = 14/203 (6%) Query: 3 ILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDT 62 +++ G PG+GK TQA+ + +Y L +I+ G+++R E+ +P+ +++ Y+S+G L+PD+ Sbjct: 30 LVLLGAPGAGKGTQAKHLVSKYSLKHISPGNLLREEMNRNSPITAQIKDYVSKGQLVPDS 89 Query: 63 IVNTLIISKLRRVRE-NFIMDGYPRTPEQVITLENY--LYDHGIKLDVAIDIYITKEESV 119 IV LI + + + + N+++DG+PR+ Q L L+ I +++ + +E V Sbjct: 90 IVIKLIENHIATIGDSNWLLDGFPRSESQAAALRASPDLFPTHI-----VELKVDQEAVV 144 Query: 120 RRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEP 179 +R+ GRR G YH+ ++PP P D ++ R DDR +++ +R+ +Y++N + Sbjct: 145 QRLGGRRFDPITGNTYHIIYDPPP-PDIAD----RVVVRTDDREDVIRERFRVYAENKDL 199 Query: 180 IIKFYQKQGIYVRIDGHGSIDEV 202 + K + + + +G +IDEV Sbjct: 200 VDKVFNHSVVSINCEGQ-TIDEV 221 >sp|P49982|KAD_GIALA ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) (AK) Length = 248 Score = 114 bits (283), Expect = 8e-25 Identities = 60/203 (29%), Positives = 119/203 (58%), Gaps = 14/203 (6%) Query: 3 ILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDT 62 +++ G PG+GK TQA+ + +Y L +I+ G+++R E+ +P+ +++ Y+S+G L+PD+ Sbjct: 30 LVLLGAPGAGKGTQAKHLVSKYSLKHISPGNLLREEMNRNSPITAQIKDYVSKGQLVPDS 89 Query: 63 IVNTLIISKLRRVRE-NFIMDGYPRTPEQVITLENY--LYDHGIKLDVAIDIYITKEESV 119 IV LI + + + + N+++DG+PR+ Q L L+ I +++ + +E V Sbjct: 90 IVIKLIENHIATIGDSNWLLDGFPRSESQAAALRASPDLFPTHI-----VELKVDQEAVV 144 Query: 120 RRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEP 179 +R+ GRR G YH+ ++PP P D ++ R DDR +++ +R+ +Y++N + Sbjct: 145 QRLGGRRFDPITGNTYHIIYDPPP-PDIAD----RVVVRTDDREDVIRERFRVYAENKDL 199 Query: 180 IIKFYQKQGIYVRIDGHGSIDEV 202 + K + + + +G +IDEV Sbjct: 200 VDKVFNHSVVSINCEGQ-TIDEV 221 >gb|AAD39831.2| (AF156853) adenylate kinase [Leishmania donovani] Length = 229 Score = 114 bits (283), Expect = 8e-25 Identities = 60/217 (27%), Positives = 116/217 (52%), Gaps = 7/217 (3%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIK-ARTPLGIEMERYLSRGDLI 59 M I++ GPP GK+T A + ERYGL Y+++ + +R ++ + ++++ + +LI Sbjct: 1 MKIVMEGPPQGGKTTVASVVKERYGLCYVSTSEAVRNAVRLGNSAYSSQLKQLIDNDELI 60 Query: 60 PDTIVNTLIISKLRRVR--ENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEE 117 PD++ ++ RR F++DG+PRT +Q +++ +K+D+ +++ I+ +E Sbjct: 61 PDSLEVKVVCEATRRPDCVNGFVLDGFPRTRKQSRMMQDL---ENVKVDIVVELEISDKE 117 Query: 118 SVRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNM 177 R GR K G +YH +NPP GK D G L+Q +D PE + +R Y + + Sbjct: 118 LQTRFGGRWYHPKSGRIYHTFYNPPLNAGKDDYTGEPLVQHSEDTPERIRQRMSQYRQQL 177 Query: 178 EPIIKFYQKQGIYVRIDGHGSIDEVWERIRPLLDYIY 214 + + +V ++ G+++ V + +LD +Y Sbjct: 178 SEVRSTFVGNA-WVTVEASGNVESVRNNVFAVLDPLY 213 >sp|Q50299|KAD_MYCPN ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|2127604|pir||S62823 adenylate kinase (EC 2.7.4.3) - Mycoplasma pneumoniae (strain ATCC 29342) >gi|2146037|pir||S73972 adenylate kinase - Mycoplasma pneumoniae (SGC3) (ATCC 29342) >gi|1215703|gb|AAC43696.1| (U34795) Adk [Mycoplasma pneumoniae] >gi|1674351|gb|AAB96294.1| (AE000061) adenylate kinase [Mycoplasma pneumoniae] Length = 215 Score = 113 bits (281), Expect = 1e-24 Identities = 62/212 (29%), Positives = 112/212 (52%), Gaps = 10/212 (4%) Query: 4 LIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDTI 63 L G PG GK T A+++ GL ++++GDI R+ ++ + L + Y+++G +PD + Sbjct: 8 LFLGAPGVGKGTLAKQVANTTGLFHLSTGDIFRSVMQEQGALSQTLAHYMNQGLYVPDEL 67 Query: 64 VNT----LIISKLRRVRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES- 118 N + + + + FI+DGYPRT Q+ L++ L +LD + ++ + Sbjct: 68 TNQTFWHFVTTHQNELHKGFILDGYPRTLNQLEFLQSKL-----QLDQVFHLKLSDPQVL 122 Query: 119 VRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNME 178 V RI R +C CG+VY+ + PP +CD C L R DD ++ KR +Y ++ Sbjct: 123 VARILNRLVCPSCGSVYNKQSKPPLKANQCDRCHATLQARNDDTEAVILKRLTLYEDTVK 182 Query: 179 PIIKFYQKQGIYVRIDGHGSIDEVWERIRPLL 210 P+I+ + KQGI I+ +++ ++ L+ Sbjct: 183 PLIEAFTKQGILTVIEAQLPLEQQVNLVQQLV 214 >gb|AAC98046.1| (AC005896) putative adenylate kinase [Arabidopsis thaliana] Length = 284 Score = 111 bits (276), Expect = 5e-24 Identities = 66/218 (30%), Positives = 114/218 (52%), Gaps = 20/218 (9%) Query: 4 LIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDTI 63 + G PG GK T A R++ G+ +IA+GD++R E+ + PL ++ +++G L+ D I Sbjct: 55 VFLGCPGVGKGTYASRLSTLLGVPHIATGDLVREELASSGPLSQKLSEIVNQGKLVSDEI 114 Query: 64 VNTLIISKLR----RVRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESV 119 + L+ +L R FI+DG+PRT Q L + +D+ +++ + +E V Sbjct: 115 IVDLLSKRLEAGEARGESGFILDGFPRTMRQAEILGDV-----TDIDLVVNLKLPEEVLV 169 Query: 120 RRISGRRICSKCGAVYHV-EFNPPKVPGKCDI----------CGGELIQRPDDRPEIVEK 168 + GRR CS+CG ++V N G+ I C +L+ R DD E+V+ Sbjct: 170 DKCLGRRTCSQCGKGFNVAHINLKGENGRPGISMDPLLPPHQCMSKLVTRADDTEEVVKA 229 Query: 169 RYDIYSKNMEPIIKFYQKQGIYVRIDGHGSIDEVWERI 206 R IY++ +P+ ++Y+ +G + D G I E W R+ Sbjct: 230 RLRIYNETSQPLEEYYRTKGKLMEFDLPGGIPESWPRL 267 >sp|O33007|KAD_MYCLE ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|11260845|pir||T45390 adenylate kinase [imported] - Mycobacterium leprae >gi|2344858|emb|CAB11460.1| (Z98756) adenylate kinase [Mycobacterium leprae] Length = 181 Score = 108 bits (268), Expect = 5e-23 Identities = 61/207 (29%), Positives = 103/207 (49%), Gaps = 35/207 (16%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 M +++ GPPG+GK TQA+R+ E+ G+ I++G++ R I+ T LG E ++YL GDL+P Sbjct: 1 MRVVLLGPPGAGKGTQAQRLAEKLGIPQISTGELFRRNIEKDTKLGHEAKKYLDAGDLVP 60 Query: 61 DTIVNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 + N L+ +L + + FI+DGYPR+ EQ L L G +D ++ +++ Sbjct: 61 ADLTNQLVDDRLNKSDTVDGFILDGYPRSLEQAKALHEMLERRGTDIDAVLEFRVSQAVV 120 Query: 119 VRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNME 178 + R+ GR R DD ++V R +IY Sbjct: 121 LERLKGR-------------------------------GRADDTDDVVINRMNIYRDETR 149 Query: 179 PIIKFYQKQGIYVRIDGHGSIDEVWER 205 ++++Y + ID G++DEV+ R Sbjct: 150 SLLEYYSSE--LKTIDAIGTMDEVFAR 174 >gi|11429144 adenylate kinase 3 alpha like [Homo sapiens] Length = 179 Score = 105 bits (260), Expect = 4e-22 Identities = 55/177 (31%), Positives = 99/177 (55%), Gaps = 7/177 (3%) Query: 45 LGIEMERYLSRGDLIPDTIVNTLIISKLRRVRE-NFIMDGYPRTPEQVITLENYLYDHGI 103 +G+ + ++ +G LIPD ++ L + +L+ + + ++++DG+PRT Q L D Sbjct: 4 IGVLAKAFIDQGKLIPDDVMTRLALHELKNLTQYSWLLDGFPRTLPQAEAL-----DRAY 58 Query: 104 KLDVAIDIYITKEESVRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRP 163 ++D I++ + E +R++ R I G VY++EFNPPK G D+ G LIQR DD+P Sbjct: 59 QIDTVINLNVPFEVIKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKP 118 Query: 164 EIVEKRYDIYSKNMEPIIKFYQKQGIYVRIDGHGSIDEVWERIRPLLDYIYNQENRR 220 E V KR Y +P++++YQK+G+ G +++W + L Q +++ Sbjct: 119 ETVIKRLKAYEDQTKPVLEYYQKKGVLETFSG-TETNKIWPYVYAFLQTKVPQRSQK 174 >gb|AAC47014.1| (U34075) nucleoside monophosphate kinase [Babesia bovis] >gi|1256578|gb|AAC48309.1| (U34076) nucleoside monophosphate kinase [Babesia bovis] Length = 241 Score = 104 bits (257), Expect = 9e-22 Identities = 60/191 (31%), Positives = 105/191 (54%), Gaps = 12/191 (6%) Query: 3 ILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDT 62 +L FG PG+GK T R + + +++SGDI+R EI+ + LG ++ + G D Sbjct: 14 LLFFGAPGTGKGTFGRLLASDLNIDHVSSGDILRKEIQRDSILGRREKKIVESGLYADDD 73 Query: 63 IVNTLIISKLRRVRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVRRI 122 + +++ ++L + I+DG PRT Q L++ I L +++D+ + + V+R+ Sbjct: 74 TICSIVSAELALASRSLILDGIPRTAAQAQFLKSISLKSNIPL-ISVDLTLDRNILVKRL 132 Query: 123 SGRRICSKCGAVYHV------EFN-PPKVPGKCDI--CGG--ELIQRPDDRPEIVEKRYD 171 GRR C++C + Y++ E+ PP +P K D+ C G +L QRPDD EI++ R Sbjct: 133 LGRRHCAQCNSSYNICTISSGEYEMPPLLPSKADLLKCNGCAKLHQRPDDTEEIIQNRLL 192 Query: 172 IYSKNMEPIIK 182 Y KN + + + Sbjct: 193 TYEKNHKEVFR 203 >sp|O24706|KAD_SYNP6 ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|2446909|dbj|BAA22468.1| (AB000111) adenylate kinase [Synechococcus sp.] Length = 186 Score = 103 bits (254), Expect = 2e-21 Identities = 56/206 (27%), Positives = 106/206 (51%), Gaps = 33/206 (16%) Query: 3 ILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDT 62 ++ GPPG+GK TQA + E+ L +I++G+++RA + A+TPLGIE + Y+ RG+L+PD+ Sbjct: 4 LIFLGPPGAGKGTQAVVVAEQLQLAHISTGELLRAAVTAQTPLGIEAKGYMDRGELVPDS 63 Query: 63 IVNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVR 120 +V L+ +L++ +I+DG+PR Q L L + ++D A+++ + + Sbjct: 64 LVLGLVRDRLQQPDTANGWILDGFPRNRSQAEALNLLLTEINQQVDRAVNLDVPDPVIIE 123 Query: 121 RISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPI 180 R+ R R DD ++ +R ++Y + P+ Sbjct: 124 RMLAR-------------------------------GRADDTESVIRRRLEVYREQTAPL 152 Query: 181 IKFYQKQGIYVRIDGHGSIDEVWERI 206 I F++ + + IDG+ + V +R+ Sbjct: 153 IDFFRDRQQLLAIDGNSEVAAVTDRL 178 >emb|CAB89615.1| (AL354533) possible adenylate kinase [Leishmania major] Length = 269 Score = 102 bits (252), Expect = 4e-21 Identities = 62/203 (30%), Positives = 107/203 (52%), Gaps = 17/203 (8%) Query: 3 ILIFGPPGSGKSTQARRITERYGLT------YIASGDIIRAEIKARTPLGIEMERYLSRG 56 +++ GPP SGK TQAR I Y +++SGD++RAE+ T LG E ++ RG Sbjct: 55 VVLAGPPASGKGTQARHICSYYKRAIGKKPVHVSSGDLLRAEVAQGTHLGKIAENFMQRG 114 Query: 57 DLIPDTIVNTLIISKLRR---VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYI 113 +L+PD+++ ++I ++L + V +++DG+PRT Q I L+ G+ + + + Sbjct: 115 ELVPDSLIISIIRNRLTQEDAVMNGWLLDGFPRTRSQAIALD----AAGLCPRIFVVLDT 170 Query: 114 TKEESVRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIY 173 + R+ GRR G +YH+++NPP P L R DD E++ R + Y Sbjct: 171 PDDVLFGRVEGRRTDPVTGIIYHLKYNPP--PENDTALLERLQHRDDDTREVLGPRLETY 228 Query: 174 SKNMEPIIKFYQKQGIYVRIDGH 196 +E ++ +Y I +DG+ Sbjct: 229 HSMVEGLLDYY--GSIMYHVDGN 249 >dbj|BAA85412.1| (AP000615) ESTs AU065232(E60855),C23624(S1554), AU078241(E60855) correspond to a region of the predicted gene.; similar to putative adenylate kinase. (AC005896) [Oryza sativa] Length = 323 Score = 102 bits (252), Expect = 4e-21 Identities = 66/255 (25%), Positives = 120/255 (46%), Gaps = 54/255 (21%) Query: 4 LIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEME------------- 50 + G PG GK T A R++ G+ +IA+GD++R E+ + PL +++ Sbjct: 64 VFLGCPGVGKGTYASRLSRLLGVPHIATGDLVRDELASSGPLSVQVRPSVHRFSARIRPS 123 Query: 51 -----------------RYLSRGDLIPDTIVNTLIISKLRRVREN----FIMDGYPRTPE 89 +++G L+ D I+ L+ +L++ E FI+DG+PRT + Sbjct: 124 CKSLIWIWFFRSSGSLAEIVNQGKLVSDEIIINLLSKRLKKGEEQGESGFILDGFPRTVK 183 Query: 90 QVITLENYLYDHGIKLDVAIDIYITKEESVRRISGRRICSKCGAVYHVE----------- 138 Q L+ +D+ +++ + ++ V + GRRIC +CG +++ Sbjct: 184 QAEILDGVT-----DIDMVVNLKLREDVLVEKCLGRRICGQCGKNFNLACIDVKGENGLP 238 Query: 139 --FNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPIIKFYQKQGIYVRIDGH 196 + P +P + C +LI R DD E+V R IY+ +P+ FY++QG + D Sbjct: 239 PIYMAPLLPP--NNCMSKLITRADDTEEVVRNRLQIYNDMSQPVEGFYRQQGKLLEFDLP 296 Query: 197 GSIDEVWERIRPLLD 211 G I E W ++ +L+ Sbjct: 297 GGIPESWPKLLHVLN 311 >gb|AAB59119.1| (M31102) adk gene product [Bacillus subtilis] Length = 116 Score = 100 bits (246), Expect = 2e-20 Identities = 45/115 (39%), Positives = 74/115 (64%), Gaps = 2/115 (1%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 MN+++ G PG+GK TQ RI E YG+ +I++GD+ RA +K TPLG+E + Y+ +G+L+P Sbjct: 1 MNLVLMGLPGAGKGTQGERIVEDYGIPHISTGDMFRAAMKEETPLGLEAKSYIDKGELVP 60 Query: 61 DTIVNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYI 113 D + ++ +L + F++DG+PRT Q LE L ++G +D I+I + Sbjct: 61 DEVTIGIVKERLGKDDCERGFLLDGFPRTVAQAEALEEILEEYGKPIDYVINIEV 115 >sp|Q9RSK7|KAD_DEIRA ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|7471085|pir||H75314 adenylate kinase - Deinococcus radiodurans (strain R1) >gi|6459913|gb|AAF11666.1|AE002046_12 (AE002046) adenylate kinase [Deinococcus radiodurans] Length = 197 Score = 99.1 bits (243), Expect = 4e-20 Identities = 60/205 (29%), Positives = 98/205 (47%), Gaps = 22/205 (10%) Query: 3 ILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDT 62 ++ GPPG+GK TQA R+ + + L +++GDI+R + T LG + + G L+PD Sbjct: 9 VIFLGPPGAGKGTQAARLAQEHQLVQLSTGDILRDHVARGTALGQQAGPLMEAGQLVPDE 68 Query: 63 IVNTLIISKLRRVRE-NFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVRR 121 ++ LI +L + I DG+PRT Q L+ L + G + + + + + R Sbjct: 69 LLIALIRDRLADMEPVRVIFDGFPRTQAQAEALDLLLEELGAPVSAVPLLEVPDQVLIDR 128 Query: 122 ISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPII 181 I R G+ + G R DD E KR +Y + +P+I Sbjct: 129 IVDR--------------------GRQAVAEGR-APRADDNEETARKRQQVYREQTQPLI 167 Query: 182 KFYQKQGIYVRIDGHGSIDEVWERI 206 +Y ++G +DG G+ DEV+ERI Sbjct: 168 DYYARRGHLYTVDGLGTPDEVYERI 192 >pir||T21947 hypothetical protein F38B2.4 - Caenorhabditis elegans >gi|3876832|emb|CAA90364.1| (Z50045) contains similarity to Pfam domain: PF00406 (Adenylate kinase), Score=278.8, E-value=2.2e-80, N=1~cDNA EST yk242b5.3 comes from this gene~cDNA EST yk242b5.5 comes from this gene~cDNA EST yk254c8.3 comes from this gene~cDNA EST yk254c8.5 comes > Length = 210 Score = 95.2 bits (233), Expect = 6e-19 Identities = 58/211 (27%), Positives = 105/211 (49%), Gaps = 35/211 (16%) Query: 5 IFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDTIV 64 I G PGSGK TQ +I +YGLT+++SGD++R E+K+ +P G ++ + G L+P +V Sbjct: 25 IVGGPGSGKGTQCDKIVAKYGLTHLSSGDLLRDEVKSGSPRGAQLTAIMESGALVPLEVV 84 Query: 65 NTLI----ISKLRRVRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVR 120 L+ + + + + F++DGYPR Q E+ + + KL + D + +E V+ Sbjct: 85 LDLVKEAMLKAIEKGSKGFLIDGYPREVAQGQQFESEIQE--AKLVLFFD--VAEETLVK 140 Query: 121 RISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPI 180 R+ R + R DD + ++KR + + P+ Sbjct: 141 RLLHR---------------------------AQTSGRADDNADTIKKRLHTFVTSTAPV 173 Query: 181 IKFYQKQGIYVRIDGHGSIDEVWERIRPLLD 211 + +Y+ +G VRI+ GS+D+++ + LD Sbjct: 174 VDYYESKGKLVRINAEGSVDDIFAVVVANLD 204 >sp|P73302|KAD_SYNY3 ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) Length = 185 Score = 94.0 bits (230), Expect = 1e-18 Identities = 55/210 (26%), Positives = 100/210 (47%), Gaps = 33/210 (15%) Query: 3 ILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDT 62 ++ G PGSGK TQA + E G+ +I++GD++R I T LG + + Y+ +G+L+PD Sbjct: 5 LIFLGAPGSGKGTQAVGLAETLGIPHISTGDMLRQAIADGTELGNQAKGYMDKGELVPDQ 64 Query: 63 IVNTLIISKL--RRVRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVR 120 ++ LI +L + + +I+DG+PR Q I L+ L + G + I++ + E V Sbjct: 65 LILGLIEERLGHKDAKAGWILDGFPRNVNQAIFLDELLVNIGHRTHWVINLKVPDEVIVE 124 Query: 121 RISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPI 180 R+ R R DD + R +Y++ P+ Sbjct: 125 RLLAR-------------------------------GRADDNETTIRNRLLVYTEQTAPL 153 Query: 181 IKFYQKQGIYVRIDGHGSIDEVWERIRPLL 210 + +YQ+QG +DG+ ++ + + L+ Sbjct: 154 MAYYQEQGKLYSLDGNQPVEAIATNLEKLV 183 >emb|CAA35713.1| (X51329) Adk N-terminal (99 AA) [Bacillus subtilis] Length = 99 Score = 90.9 bits (222), Expect = 1e-17 Identities = 40/97 (41%), Positives = 64/97 (65%), Gaps = 2/97 (2%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 MN+++ G PG+GK TQ RI E YG+ +I++GD+ RA +K TPLG+E + Y+ +G+L+P Sbjct: 1 MNLVLMGLPGAGKGTQGERIVEDYGIPHISTGDMFRAAMKEETPLGLEAKSYIDKGELVP 60 Query: 61 DTIVNTLIISKLRR--VRENFIMDGYPRTPEQVITLE 95 D + ++ +L + F++DG+PRT Q LE Sbjct: 61 DEVTIGIVKERLGKDDCERGFLLDGFPRTVAQAEALE 97 >gb|AAG09688.1|AF183419_1 (AF183419) GTP:AMP phosphotransferase [Homo sapiens] Length = 157 Score = 89.7 bits (219), Expect = 3e-17 Identities = 49/155 (31%), Positives = 85/155 (54%), Gaps = 7/155 (4%) Query: 67 LIISKLRRVRE-NFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVRRISGR 125 L + +L+ + + ++++DG+PRT Q L D ++D I++ + E +R++ R Sbjct: 4 LALHELKNLTQYSWLLDGFPRTLPQAEAL-----DRAYQIDTVINLNVPFEVIKQRLTAR 58 Query: 126 RICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPIIKFYQ 185 I G VY++EFNPPK G D+ G LIQR DD+PE V KR Y +P++++YQ Sbjct: 59 WIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQTKPVLEYYQ 118 Query: 186 KQGIYVRIDGHGSIDEVWERIRPLLDYIYNQENRR 220 K+G+ G +++W + L Q +++ Sbjct: 119 KKGVLETFSG-TETNKIWPYVYAFLQTKVPQRSQK 152 >pir||T35552 adenylate kinase - Streptomyces coelicolor (fragment) >gi|3449235|emb|CAA20379.1| (AL031317) adenylate kinase [Streptomyces coelicolor A3(2)] Length = 94 Score = 88.5 bits (216), Expect = 6e-17 Identities = 41/85 (48%), Positives = 54/85 (63%), Gaps = 1/85 (1%) Query: 122 ISGRRIC-SKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPI 180 I+GRR+C ++ V+HV + PPK G CD+CGGEL QR DD E V KR ++Y EPI Sbjct: 1 IAGRRVCRNEPKHVFHVTYTPPKKEGVCDVCGGELYQRDDDSEETVRKRLEVYHTQTEPI 60 Query: 181 IKFYQKQGIYVRIDGHGSIDEVWER 205 I +Y+ QG+ I G +DEV R Sbjct: 61 IDYYKSQGLVATIAATGPVDEVTRR 85 >pir||S74491 adenylate kinase (EC 2.7.4.3) 1 - Synechocystis sp. (strain PCC 6803) >gi|1651715|dbj|BAA16643.1| (D90899) adenylate kinase [Synechocystis sp.] Length = 181 Score = 87.8 bits (214), Expect = 1e-16 Identities = 58/208 (27%), Positives = 99/208 (46%), Gaps = 33/208 (15%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 M +++ G PGSGKSTQ+ +++ L I+ G I+R I TPLGI+ + Y+ RGDL+P Sbjct: 1 MRLVMLGGPGSGKSTQSHNLSQELKLPVISMGGILREAIANATPLGIKAKPYVERGDLLP 60 Query: 61 DTIVNTLIISKLRRV--RENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 D ++ I +L + + +I++GYPRT Q L+ L D G LD A+ + I + Sbjct: 61 DPMMIEFIQQRLVQEDGGQGWILEGYPRTAFQAEELDFLLEDLGQPLDWALYLKIDEATM 120 Query: 119 VRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNME 178 V R R + DD PE + R + + Sbjct: 121 VERSLNRSLF-------------------------------DDHPEAITTRIGKFHEYTV 149 Query: 179 PIIKFYQKQGIYVRIDGHGSIDEVWERI 206 P++++Y + + ++ + +D+V + I Sbjct: 150 PLLEYYAAKQNLLTVNAYPEVDQVTKLI 177 >gb|AAD00547.1| (U83616) UMP-CMP kinase [Entamoeba histolytica] Length = 202 Score = 86.6 bits (211), Expect = 2e-16 Identities = 51/208 (24%), Positives = 103/208 (49%), Gaps = 33/208 (15%) Query: 3 ILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKAR-TPLGIEMERYLSRGDLIPD 61 + G PG+GK TQ ++I +Y +T++++GD++RAE+K + G ++ + G ++P Sbjct: 9 LFCLGGPGAGKGTQCQKIINKYPITHLSAGDLLRAEVKREGSQNGQLIQTLIKEGKIVPA 68 Query: 62 TIVNTLIISKLRRVREN-FIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYI--TKEES 118 + L+++ +R FI+DG+PR E +L + + +D A+ ++I ++E Sbjct: 69 AVTVELLLNAIRNDEHKVFIIDGFPRNAENKEAW--FLQANKVNIDTALCVFIDVSEETM 126 Query: 119 VRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNME 178 + RI R + S R DD + + KR+ Y Sbjct: 127 INRIHKRSVNS---------------------------GRVDDNDDSLMKRFRTYKSETL 159 Query: 179 PIIKFYQKQGIYVRIDGHGSIDEVWERI 206 P+I+ ++ + +R+ G GS+D+++ +I Sbjct: 160 PVIESFENENKLLRVSGEGSVDDIFNKI 187 >sp|P38372|KAD_BACHD ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|348302|pir||C44859 adenylate kinase (EC 2.7.4.3) - Bacillus sp. (strain C125) (fragment) >gi|2160219|dbj|BAA01192.1| (D10360) adenylate kinase [Bacillus sp.] Length = 107 Score = 86.6 bits (211), Expect = 2e-16 Identities = 39/100 (39%), Positives = 66/100 (66%), Gaps = 2/100 (2%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 MN+ + G PG+GK TQA +I E+YG+ +I++GD+ RA +K T LG++ + Y+ G+L+P Sbjct: 1 MNLNLMGLPGAGKGTQAEKIIEKYGIPHISTGDMFRAAMKNETELGLKAKSYMDAGELVP 60 Query: 61 DTIVNTLIISKLRR--VRENFIMDGYPRTPEQVITLENYL 98 D + ++ +L + + F++DG+PRT Q LE+ L Sbjct: 61 DEVTIGIVRDRLSQDDCQNGFLLDGFPRTVAQAEALEDIL 100 >sp|P25824|KAD_SCHMA ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) (AK) >gi|161048|gb|AAA29907.1| (M80542) nucleoside monophosphate kinase [Schistosoma mansoni] Length = 197 Score = 85.8 bits (209), Expect = 4e-16 Identities = 50/204 (24%), Positives = 103/204 (49%), Gaps = 28/204 (13%) Query: 3 ILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDT 62 I + G PGSGK TQ ++ +++ +++SGD++RAE+++ +P G E++ + RG+L+P Sbjct: 12 IFVLGGPGSGKGTQCEKLVQKFHFNHLSSGDLLRAEVQSGSPKGKELKAMMERGELVPLE 71 Query: 63 IVNTLIISKLRRVRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVRRI 122 +V L+ + ++ R P ++ D GIK + Sbjct: 72 VVLALLKEAMINWLTKIVISLSIRYPREL--------DQGIKFE---------------- 107 Query: 123 SGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPIIK 182 + +C C V + + + +V K + E R DD E + KR+ +++ +P+I+ Sbjct: 108 --KEVC-PCLCVINFDVS-EEVMRKRLLKRAETSNRVDDNEETIVKRFRTFNELTKPVIE 163 Query: 183 FYQKQGIYVRIDGHGSIDEVWERI 206 Y++Q + ID G++D +++++ Sbjct: 164 HYKQQNKVITIDASGTVDAIFDKV 187 >emb|CAC12706.1| (AL136231) bA6J24.5 (Adenylate kinase 3 alpha) [Homo sapiens] Length = 136 Score = 82.3 bits (200), Expect = 4e-15 Identities = 45/137 (32%), Positives = 72/137 (51%), Gaps = 6/137 (4%) Query: 84 YPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVRRISGRRICSKCGAVYHVEFNPPK 143 +PRT Q L D ++D I++ + E +R++ R I G VY++EFNPPK Sbjct: 1 FPRTLPQAEAL-----DRAYQIDTVINLNVPFEVIKQRLTARWIHPASGRVYNIEFNPPK 55 Query: 144 VPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPIIKFYQKQGIYVRIDGHGSIDEVW 203 G D+ G LIQR DD+PE V KR Y +P++++YQK+G+ G +++W Sbjct: 56 TVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQTKPVLEYYQKKGVLETFSG-TETNKIW 114 Query: 204 ERIRPLLDYIYNQENRR 220 + L Q +++ Sbjct: 115 PYVYAFLQTKVPQRSQK 131 >gb|AAC28787.1| (AF047722) adenylate kinase [Trypanosoma brucei rhodesiense] Length = 209 Score = 80.8 bits (196), Expect = 1e-14 Identities = 46/153 (30%), Positives = 83/153 (54%), Gaps = 8/153 (5%) Query: 1 MNILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIP 60 + I I GP GSGK TQ + I +R G+ I+SG ++ +++ + Y+SRG+ +P Sbjct: 50 LQIFIAGPAGSGKRTQCKNIADRLGVVLISSGQVLTRGVESGSETSQLAHSYVSRGERVP 109 Query: 61 DTIVNTLIISKLRR---VRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEE 117 DT+V+ ++ +L + + ++++GYPR +Q +E + G+ V I + + ++ Sbjct: 110 DTLVSMIMKDRLSQSDACEKGWLVEGYPRNAQQAQAVE----ECGVIPQVFILLDLPEDL 165 Query: 118 SVRRISGRRICSKCGAVYHVEFNPPKVPGKCDI 150 S RR+ RR YH+ NPP G+C + Sbjct: 166 SFRRLEHRRYDPATNKXYHMLDNPPP-GGRCRV 197 >gi|11424506 adenylate kinase 5 [Homo sapiens] Length = 197 Score = 80.8 bits (196), Expect = 1e-14 Identities = 60/224 (26%), Positives = 102/224 (44%), Gaps = 52/224 (23%) Query: 3 ILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDT 62 I I G PGSGK TQ ++ E+YG T++++G+++R E+ + + + + RGDL+P Sbjct: 14 IFIIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELASESERSKLIRDIMERGDLVPSG 73 Query: 63 IVNTLI----ISKLRRVRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 IV L+ ++ L R F++DGYPR +Q EE Sbjct: 74 IVLELLKEAMVASLGDTR-GFLIDGYPREVKQ------------------------GEEF 108 Query: 119 VRRISGRR--ICSKCGAVYHVEFNPPKVPGKCDICGGELIQRP------DDRPEIVEKRY 170 RRI + IC C A D L+QR DD + + KR Sbjct: 109 GRRIGDPQLVICMDCSA---------------DTMTNRLLQRSRSSLPVDDTTKTIAKRL 153 Query: 171 DIYSKNMEPIIKFYQKQGIYVRIDGHGSIDEVWERIRPLLDYIY 214 + Y + P+I +Y+ + +I+ G+ ++V+ ++ +D I+ Sbjct: 154 EAYYRASIPVIAYYETKTQLHKINAEGTPEDVFLQLCTAIDSIF 197 >gb|AAF49942.1| (AE003542) CG17146 gene product [Drosophila melanogaster] Length = 201 Score = 80.4 bits (195), Expect = 2e-14 Identities = 51/220 (23%), Positives = 104/220 (47%), Gaps = 34/220 (15%) Query: 3 ILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDT 62 I I G PG GK TQ +I E+YG T+++SGD++R E+ + + G +++ ++ G L+ + Sbjct: 7 IWILGGPGCGKGTQCAKIVEKYGFTHLSSGDLLRNEVASGSDKGRQLQAVMASGGLVSND 66 Query: 63 IVNTLIISKLRRVR---ENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESV 119 V +L+ + R + + F++DGYPR Q I E + D+A+ +++ V Sbjct: 67 EVLSLLNDAITRAKGSSKGFLIDGYPRQKNQGIEFEARI----APADLALYFECSEDTMV 122 Query: 120 RRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEP 179 +RI R S ++R DD + + R + +N Sbjct: 123 QRIMARAAAS-------------------------AVKRDDDNEKTIRARLLTFKQNTNA 157 Query: 180 IIKFYQKQGIYVRIDGHGSIDEVWERIRPLLDYIYNQENR 219 I++ Y+ + + I+ +D+++ + +D + ++ + Sbjct: 158 ILELYEPKTL--TINAERDVDDIFLEVVQAIDCVLKKKQQ 195 >gi|6912232 adenylate kinase 5 [Homo sapiens] >gi|9296996|sp|Q9Y6K8|KAD5_HUMAN ADENYLATE KINASE ISOENZYME 5 (ATP-AMP TRANSPHOSPHORYLASE) >gi|4691541|gb|AAD27956.1|AF062595_1 (AF062595) adenylate kinase 5 [Homo sapiens] Length = 198 Score = 79.6 bits (193), Expect = 3e-14 Identities = 60/223 (26%), Positives = 101/223 (44%), Gaps = 52/223 (23%) Query: 3 ILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEIKARTPLGIEMERYLSRGDLIPDT 62 I I G PGSGK TQ ++ E+YG T++++G+++R E+ + + + + RGDL+P Sbjct: 14 IFIIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELASESERSKLIRDIMERGDLVPSG 73 Query: 63 IVNTLI----ISKLRRVRENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEES 118 IV L+ ++ L R F++DGYPR +Q EE Sbjct: 74 IVLELLKEAMVASLGDTR-GFLIDGYPREVKQ------------------------GEEF 108 Query: 119 VRRISGRR--ICSKCGAVYHVEFNPPKVPGKCDICGGELIQRP------DDRPEIVEKRY 170 RRI + IC C A D L+QR DD + + KR Sbjct: 109 GRRIGDPQLVICMDCSA---------------DTMTNRLLQRSRSSLPVDDTTKTIAKRL 153 Query: 171 DIYSKNMEPIIKFYQKQGIYVRIDGHGSIDEVWERIRPLLDYI 213 + Y + P+I +Y+ + +I+ G+ ++V+ ++ +D I Sbjct: 154 EAYYRASIPVIAYYETKTQLHKINAEGTPEDVFLQLCTAIDSI 196 >dbj|BAA14303.1| (D90259) adenylate kinase [Escherichia coli] Length = 107 Score = 76.1 bits (184), Expect = 3e-13 Identities = 42/103 (40%), Positives = 57/103 (54%), Gaps = 5/103 (4%) Query: 113 ITKEESVRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDI 172 + E V RI GRR+ + G VYHV+FNPPKV GK D+ G EL R DD+ E V KR Sbjct: 4 VPDELIVDRIVGRRVHAPSGRVYHVKFNPPKVEGKDDVTGEELTTRKDDQEETVRKRLVE 63 Query: 173 YSKNMEPIIKFYQKQG-----IYVRIDGHGSIDEVWERIRPLL 210 Y + P+I +Y K+ Y ++DG + EV + +L Sbjct: 64 YHQMTAPLIGYYSKEAEAGNTKYAKVDGTKPVAEVRADLEKIL 106 >dbj|BAA28693.1| (AB005742) UMP-CMP kinase [Lentinula edodes] Length = 227 Score = 75.7 bits (183), Expect = 4e-13 Identities = 56/219 (25%), Positives = 101/219 (45%), Gaps = 45/219 (20%) Query: 3 ILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEI-KARTPLGIEMERYLSRGDLIPD 61 I + G PG+GK TQ R+ E + +++++GD++RAE + + G ++ + G ++P Sbjct: 28 IFVLGGPGAGKGTQCARLVEDFSFSHLSAGDLLRAEQHREGSEYGQLIQTCIKEGSIVPM 87 Query: 62 TIVNTLIISKL------RRVREN-------FIMDGYPRTPEQVITLENYLYDHGIKLDVA 108 + L+ + + RR E F++DG+PR +Q E + +D G K Sbjct: 88 EVTVKLLENAMTATLAERRSGEGWTDGQGRFLIDGFPRKMDQA---EKFEHDVG-KATAV 143 Query: 109 IDIYITKEESVRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEK 168 + T+E + R+ R G+ R DD E ++K Sbjct: 144 LFFSTTQEVMLDRLLER---------------------------GKTSGREDDNVESIKK 176 Query: 169 RYDIYSKNMEPIIKFYQKQGIYVRIDGHGSIDEVWERIR 207 R++ Y + P+I+ Y+K G + ID SI+EV ++ R Sbjct: 177 RFNTYKEQTMPVIEHYEKLGKVIEIDSSVSIEEVHQKTR 215 >gb|AAF56560.1| (AE003754) Dak1 gene product [Drosophila melanogaster] Length = 253 Score = 75.7 bits (183), Expect = 4e-13 Identities = 51/209 (24%), Positives = 97/209 (46%), Gaps = 29/209 (13%) Query: 3 ILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAE-IKARTPLGIEMERYLSRGDLIPD 61 + + G PG+GK TQ RI +R+ T++++GD++R E + + G +E Y+ G ++P Sbjct: 66 VFVLGGPGAGKGTQCSRIVDRFQFTHLSAGDLLREERSREGSEFGNLIEDYIRNGKIVPV 125 Query: 62 TIVNTLIISKLRRV-RENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVR 120 + +L+ + ++ + F++DG+PR + L+ + K+D ++ Sbjct: 126 EVTCSLLENAMKASGKSRFLIDGFPRNQD---NLDGWNRQMSEKVDFQFVLFFD------ 176 Query: 121 RISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPI 180 G +C K +C G R DD + ++KR Y+ + PI Sbjct: 177 --CGEDVCVK----------------RCLGRGQSGSGRTDDNLDSLKKRISTYNNDSLPI 218 Query: 181 IKFYQKQGIYVRIDGHGSIDEVWERIRPL 209 IKF++ G RID +EV+ + + Sbjct: 219 IKFFEGAGQVKRIDASPDAEEVFGEVEKI 247 >dbj|BAA86920.1| (AB025924) Dak1 [Drosophila melanogaster] >gi|6451558|dbj|BAA86921.1| (AB025925) Dak1L [Drosophila melanogaster] Length = 196 Score = 74.9 bits (181), Expect = 8e-13 Identities = 51/209 (24%), Positives = 96/209 (45%), Gaps = 29/209 (13%) Query: 3 ILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAE-IKARTPLGIEMERYLSRGDLIPD 61 + + G PG+GK TQ RI +R+ T++++GD++R E + + G +E Y+ G ++P Sbjct: 9 VFVLGGPGAGKGTQCSRIVDRFQFTHLSAGDLLREERSREGSEFGNLIEDYIRNGKIVPV 68 Query: 62 TIVNTLIISKLRRV-RENFIMDGYPRTPEQVITLENYLYDHGIKLDVAIDIYITKEESVR 120 + +L+ + ++ + F++DG+PR + L+ + K+D + Sbjct: 69 EVTCSLLENAMKASGKSRFLIDGFPRNQDN---LDGWNRQMSEKVDFQFVFFFD------ 119 Query: 121 RISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEKRYDIYSKNMEPI 180 G +C K +C G R DD + ++KR Y+ + PI Sbjct: 120 --CGEDVCVK----------------RCLGRGQSGSGRTDDNLDSLKKRISTYNNDSLPI 161 Query: 181 IKFYQKQGIYVRIDGHGSIDEVWERIRPL 209 IKF++ G RID +EV+ + + Sbjct: 162 IKFFEGAGQVKRIDASPDAEEVFGEVEKI 190 >pir||JC6572 cytidylate kinase (EC 2.7.4.14) - shiitake mushroom Length = 227 Score = 73.4 bits (177), Expect = 2e-12 Identities = 54/219 (24%), Positives = 99/219 (44%), Gaps = 45/219 (20%) Query: 3 ILIFGPPGSGKSTQARRITERYGLTYIASGDIIRAEI-KARTPLGIEMERYLSRGDLIPD 61 I + G PG+GK TQ R+ E + +++++GD++RAE + + G ++ + G +P Sbjct: 28 IFVLGGPGAGKGTQCARLVEDFSFSHLSAGDLLRAEQHREGSEYGQLIQTCIKEGSTVPM 87 Query: 62 TIVNTLIISKL------RRVREN-------FIMDGYPRTPEQVITLENYLYDHGIKLDVA 108 + L+ + + RR E F++DG+PR +Q E H + A Sbjct: 88 EVTVKLLENAMTATLAERRSGEGWTDGQGRFLIDGFPRKMDQAEKFE-----HDVGKATA 142 Query: 109 IDIYITKEESVRRISGRRICSKCGAVYHVEFNPPKVPGKCDICGGELIQRPDDRPEIVEK 168 + + T +E + R+ + G+ R DD E ++K Sbjct: 143 VKFFSTTQE----VMLDRLLER----------------------GKTSGREDDNVESIKK 176 Query: 169 RYDIYSKNMEPIIKFYQKQGIYVRIDGHGSIDEVWERIR 207 R++ Y + P+I+ Y+K G + ID SI+EV ++ R Sbjct: 177 RFNTYKEQTMPVIEHYEKLGKVIEIDSSVSIEEVHQKTR 215 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.322 0.144 0.429 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 90922768 Number of Sequences: 2977 Number of extensions: 3879499 Number of successful extensions: 15181 Number of sequences better than 1.0e-10: 165 Number of HSP's better than 0.0 without gapping: 106 Number of HSP's successfully gapped in prelim test: 59 Number of HSP's that attempted gapping in prelim test: 14785 Number of HSP's gapped (non-prelim): 193 length of query: 220 length of database: 189,106,746 effective HSP length: 51 effective length of query: 169 effective length of database: 158,583,909 effective search space: 26800680621 effective search space used: 26800680621 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.8 bits) S2: 163 (67.9 bits)