BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0744 (lhr-2) DE:large helicase-related protein (lhr-2)
(867 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||D75091 large helicase-related protein (lhr-2) PAB0744 - Pyr... 1710 0.0
sp|Q57742|HELX_METJA PUTATIVE ATP-DEPENDENT HELICASE MJ0294 >gi|... 987 0.0
gi|11500031 large helicase-related protein (lhr-2) [Archaeoglobu... 968 0.0
pir||G71051 probable ATP-dependent helicase LHR - Pyrococcus hor... 931 0.0
sp|O27830|HELX_METTH PUTATIVE ATP-DEPENDENT HELICASE MTH1802 >gi... 872 0.0
pir||C72521 hypothetical protein APE2144 - Aeropyrum pernix (str... 868 0.0
sp|P95949|HELX_SULSO PUTATIVE ATP-DEPENDENT HELICASE C04010 >gi|... 841 0.0
gb|AAK40467.1| ATP-dependent helicase [Sulfolobus solfataricus] 841 0.0
emb|CAC11727.1| (AL445064) hypothetical protein [Thermoplasma ac... 764 0.0
pir||F83237 probable ATP-dependent DNA helicase PA3272 [imported... 457 e-127
pir||T35694 ATP dependent DNA helicase - Streptomyces coelicolor... 416 e-115
pir||A70982 probable ATP-dependent helicase lhr - Mycobacterium ... 404 e-111
sp|P30015|LHR_ECOLI PROBABLE ATP-DEPENDENT HELICASE LHR (LARGE H... 376 e-103
pir||C71004 probable ATP-dependent helicase - Pyrococcus horikos... 373 e-102
gi|11498749 large helicase-related protein (lhr-1) [Archaeoglobu... 358 2e-97
pir||B75127 large helicase-related protein (lhr-1) PAB1817 - Pyr... 348 1e-94
emb|CAC11967.1| (AL445065) Large helicase related protein [Therm... 315 2e-84
gb|AAG19610.1| (AE005050) ATP-dependent helicase; HelA [Halobact... 303 4e-81
gb|AAK40723.1| ATP-dependent helicase [Sulfolobus solfataricus] 282 8e-75
pir||G72526 hypothetical protein APE2188 - Aeropyrum pernix (str... 277 3e-73
gb|AAK41239.1| ATP-dependent helicase [Sulfolobus solfataricus] 266 9e-70
pir||A69140 ATP-dependent helicase - Methanobacterium thermoauto... 182 2e-44
pir||T35049 probable ATP-dependent helicase - Streptomyces coeli... 153 9e-36
gb|AAK40384.1| ATP-dependent helicase [Sulfolobus solfataricus] 151 3e-35
pir||F71092 ATP-dependent RNA helicase homolog PH1003 - Pyrococc... 132 2e-29
pir||E64496 ATP-dependent RNA helicase homolog MJ1574 - Methanoc... 126 9e-28
sp|P50830|YPRA_BACSU HYPOTHETICAL HELICASE IN PONA-COTD INTERGEN... 121 4e-26
gi|6320497 Ydr291wp [Saccharomyces cerevisiae] >gi|2131417|pir||... 114 4e-24
dbj|BAB05483.1| (AP001513) ATP-dependent RNA helicase [Bacillus ... 114 4e-24
pir||B75073 ATP-dependent RNA helicase homolog PAB1722 - Pyrococ... 112 1e-23
gi|11499982 ATP-dependent RNA helicase, putative [Archaeoglobus ... 109 1e-22
pir||T43854 helicase [imported] - Pyrococcus furiosus >gi|337450... 108 3e-22
pir||E71073 hypothetical protein PH1280 - Pyrococcus horikoshii ... 104 6e-21
pir||T36671 probable helicase - Streptomyces coelicolor >gi|4539... 102 2e-20
pir||B75135 DNA helicase related protein PAB0592 - Pyrococcus ab... 100 8e-20
pir||F69164 ATP-dependent RNA helicase homolog MTH492 - Methanob... 99 2e-19
gi|11500032 SKI2-family helicase [Archaeoglobus fulgidus] 99 2e-19
pir||B70564 hypothetical protein Rv3649 - Mycobacterium tubercul... 96 2e-18
gi|9755332 C4 zinc finger DNA-binding protein of low sequence sp... 94 6e-18
gb|AAD30595.1|AC007369_5 (AC007369) Putative RNA helicase [Arabi... 92 2e-17
pir||T00936 ATP-dependent RNA helicase homolog T24P15.18 - Arabi... 91 5e-17
pir||S61610 HFM1 protein - yeast (Saccharomyces cerevisiae) >gi|... 89 2e-16
pir||H70414 conserved hypothetical protein aq_1328 - Aquifex aeo... 88 5e-16
pir||T39188 probable U5 snRNP-specific 200kd protein - fission y... 87 8e-16
sp|P51979|HFM1_YEAST HFM1 PROTEIN >gi|780546|gb|AAA93159.1| (U22... 87 1e-15
dbj|BAB10376.1| (AB006696) RNA helicase [Arabidopsis thaliana] 85 3e-15
gi|6321856 RRP3 is a DEAD box gene homologous to eIF-4a which en... 85 4e-15
gi|6321020 putative ATP-dependent RNA helicase; Brr2p [Saccharom... 85 4e-15
pir||T38420 probable dna helicases - fission yeast (Schizosaccha... 83 9e-15
pir||H64474 hypothetical protein MJ1401 - Methanococcus jannasch... 82 3e-14
pir||E72775 probable helicase APE0191 - Aeropyrum pernix (strain... 82 3e-14
gb|AAG20465.1| (AE005119) DNA repair protein; Rad24b [Halobacter... 81 5e-14
dbj|BAB14698.1| (AK023840) unnamed protein product [Homo sapiens] 80 1e-13
pir||C64440 DNA repair protein RAD24 homolog (intein-containing)... 80 1e-13
pir||C69187 conserved hypothetical protein MTH656 - Methanobacte... 80 1e-13
dbj|BAB14906.1| (AK024391) unnamed protein product [Homo sapiens] 78 3e-13
emb|CAC11964.1| (AL445065) DNA helicase related protein [Thermop... 78 3e-13
dbj|BAB01770.1| (AB022215) DEAD-Box RNA helicase-like protein [A... 78 4e-13
emb|CAA94089.1| (Z70200) U5 snRNP-specific 200kD protein [Homo s... 77 7e-13
dbj|BAA91812.1| (AK001652) unnamed protein product [Homo sapiens] 77 7e-13
dbj|BAB12216.1| (AB047802) vasa homolog [Ciona savignyi] 76 2e-12
dbj|BAB12217.1| (AB047803) vasa homolog [Ciona savignyi] 76 2e-12
gi|6321963 DEAD-box protein; Dbp8p [Saccharomyces cerevisiae] >g... 76 2e-12
gb|AAF55204.1| (AE003709) CG5205 gene product [Drosophila melano... 75 3e-12
dbj|BAA19572.1| (D86601) DEAD family RNA helicase; germ cell spe... 74 6e-12
pir||T40504 atp-dependent, dead box, rna helicase - fission yeas... 74 6e-12
pir||S01676 ATP-dependent RNA helicase homolog - fruit fly (Dros... 73 1e-11
pir||A31922 ATP-dependent RNA helicase homolog - fruit fly (Dros... 73 1e-11
prf||1413329A gene vasa [Drosophila melanogaster] 73 1e-11
sp|P09052|VASA_DROME VASA PROTEIN >gi|7446078|pir||A58768 ATP-de... 73 1e-11
gb|AAF39890.1| (AC006661) contains similarity to Pfam families P... 72 3e-11
pir||B45065 probable helicase - Escherichia coli (fragment) 71 4e-11
emb|CAA09374.1| (AJ010840) ATP-dependent RNA helicase [Homo sapi... 71 4e-11
gi|4759030 RecQ protein-like 4; RecQ protein 4 [Homo sapiens] >g... 71 4e-11
gb|AAF44917.1|AE003406_122 (AE003416) symbol=vas; synonym=BG:DS0... 71 4e-11
dbj|BAA34994.1| (AB017003) DjVLGB [Dugesia japonica] 71 5e-11
sp|P25888|RHLE_ECOLI PUTATIVE ATP-DEPENDENT RNA HELICASE RHLE >g... 71 7e-11
>pir||D75091 large helicase-related protein (lhr-2) PAB0744 - Pyrococcus abyssi
(strain Orsay) >gi|5458545|emb|CAB50033.1| (AJ248286)
large helicase-related protein (lhr-2) [Pyrococcus
abyssi]
Length = 867
Score = 1710 bits (4381), Expect = 0.0
Identities = 867/867 (100%), Positives = 867/867 (100%)
Query: 1 MMSEIKWANREYSDEEIYSILDPIVREWFKRKFKSFTPPQRYAIVEIHKGENVLISSPTG 60
MMSEIKWANREYSDEEIYSILDPIVREWFKRKFKSFTPPQRYAIVEIHKGENVLISSPTG
Sbjct: 1 MMSEIKWANREYSDEEIYSILDPIVREWFKRKFKSFTPPQRYAIVEIHKGENVLISSPTG 60
Query: 61 SGKTLSAFLAIISELISLGRRGKLEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQE 120
SGKTLSAFLAIISELISLGRRGKLEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQE
Sbjct: 61 SGKTLSAFLAIISELISLGRRGKLEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQE 120
Query: 121 LNEEIPEIRVAVRTSDTSSYEKSKMLKMPPHILITTPESLAIALNAPRFREKLRDVKWVI 180
LNEEIPEIRVAVRTSDTSSYEKSKMLKMPPHILITTPESLAIALNAPRFREKLRDVKWVI
Sbjct: 121 LNEEIPEIRVAVRTSDTSSYEKSKMLKMPPHILITTPESLAIALNAPRFREKLRDVKWVI 180
Query: 181 VDEVHALAENKRGSHLALTLERLRELTKRDFVRIGLSATIHPLEEVAKFVFGFSDDGKPR 240
VDEVHALAENKRGSHLALTLERLRELTKRDFVRIGLSATIHPLEEVAKFVFGFSDDGKPR
Sbjct: 181 VDEVHALAENKRGSHLALTLERLRELTKRDFVRIGLSATIHPLEEVAKFVFGFSDDGKPR 240
Query: 241 PGLIVDVSFAKKTKITVESVVEDLVYTPANVLNEALYRRIGELVRSRKTTLIFTNTRSGA 300
PGLIVDVSFAKKTKITVESVVEDLVYTPANVLNEALYRRIGELVRSRKTTLIFTNTRSGA
Sbjct: 241 PGLIVDVSFAKKTKITVESVVEDLVYTPANVLNEALYRRIGELVRSRKTTLIFTNTRSGA 300
Query: 301 ERVAYHLKKMFPEWEDKIEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTI 360
ERVAYHLKKMFPEWEDKIEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTI
Sbjct: 301 ERVAYHLKKMFPEWEDKIEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTI 360
Query: 361 DLVILIGSPKSVNRALQRIGRAGHRLHEVSEGVILALDRDDLVEVTVLAHNARKRKLDRI 420
DLVILIGSPKSVNRALQRIGRAGHRLHEVSEGVILALDRDDLVEVTVLAHNARKRKLDRI
Sbjct: 361 DLVILIGSPKSVNRALQRIGRAGHRLHEVSEGVILALDRDDLVEVTVLAHNARKRKLDRI 420
Query: 421 KIPKNPLDVLVQHLLGMALERVWEVEEAYKVVRRAYPYHDLPFEDFINVLKYLAGEFSGL 480
KIPKNPLDVLVQHLLGMALERVWEVEEAYKVVRRAYPYHDLPFEDFINVLKYLAGEFSGL
Sbjct: 421 KIPKNPLDVLVQHLLGMALERVWEVEEAYKVVRRAYPYHDLPFEDFINVLKYLAGEFSGL 480
Query: 481 EERKVYAKIWLENGKFGKRGKMTRAIYYMNTGTIPDEAKIDVFTMDKKYIGTVEEEFAER 540
EERKVYAKIWLENGKFGKRGKMTRAIYYMNTGTIPDEAKIDVFTMDKKYIGTVEEEFAER
Sbjct: 481 EERKVYAKIWLENGKFGKRGKMTRAIYYMNTGTIPDEAKIDVFTMDKKYIGTVEEEFAER 540
Query: 541 LIPGDIFVLAGRTYEFVKSRGNKIYVIPREGVKPTIPSWFSEMLPLSFDLALDIQKFRRE 600
LIPGDIFVLAGRTYEFVKSRGNKIYVIPREGVKPTIPSWFSEMLPLSFDLALDIQKFRRE
Sbjct: 541 LIPGDIFVLAGRTYEFVKSRGNKIYVIPREGVKPTIPSWFSEMLPLSFDLALDIQKFRRE 600
Query: 601 VKSLLNDEDAELKLMEKYGIDEITAKAIISYFREQANYSVIPDDETVLVEIVKEGNVVKY 660
VKSLLNDEDAELKLMEKYGIDEITAKAIISYFREQANYSVIPDDETVLVEIVKEGNVVKY
Sbjct: 601 VKSLLNDEDAELKLMEKYGIDEITAKAIISYFREQANYSVIPDDETVLVEIVKEGNVVKY 660
Query: 661 FFHTLIGRRANDALSRAFAYLISKRKRCNVGMAITDNGFMLKVPRDKELSQEEVLELFQV 720
FFHTLIGRRANDALSRAFAYLISKRKRCNVGMAITDNGFMLKVPRDKELSQEEVLELFQV
Sbjct: 661 FFHTLIGRRANDALSRAFAYLISKRKRCNVGMAITDNGFMLKVPRDKELSQEEVLELFQV 720
Query: 721 ENLRETLKRALDNTELLKRRFRHVANRGLLVLRRYMGRKKSLSRQQMNAQTLLNFLKRNY 780
ENLRETLKRALDNTELLKRRFRHVANRGLLVLRRYMGRKKSLSRQQMNAQTLLNFLKRNY
Sbjct: 721 ENLRETLKRALDNTELLKRRFRHVANRGLLVLRRYMGRKKSLSRQQMNAQTLLNFLKRNY 780
Query: 781 PEFPLLKEVYREILEDKMDIENAELFLKWIKEGKVKIVVEEHSYPSPFAFNLEVVGASDV 840
PEFPLLKEVYREILEDKMDIENAELFLKWIKEGKVKIVVEEHSYPSPFAFNLEVVGASDV
Sbjct: 781 PEFPLLKEVYREILEDKMDIENAELFLKWIKEGKVKIVVEEHSYPSPFAFNLEVVGASDV 840
Query: 841 VLMEDRRELIRQLHQKIMAIIASQGQD 867
VLMEDRRELIRQLHQKIMAIIASQGQD
Sbjct: 841 VLMEDRRELIRQLHQKIMAIIASQGQD 867
>sp|Q57742|HELX_METJA PUTATIVE ATP-DEPENDENT HELICASE MJ0294 >gi|2129094|pir||G64336
large helicase related protein LHR homolog -
Methanococcus jannaschii >gi|1591016|gb|AAB98279.1|
(U67484) large helicase-related protein (LHR), probably
RNA helicase [Methanococcus jannaschii]
Length = 841
Score = 987 bits (2525), Expect = 0.0
Identities = 508/865 (58%), Positives = 665/865 (76%), Gaps = 25/865 (2%)
Query: 2 MSEIKWANREYSDEEIYSILDPIVREWFKRKFKSFTPPQRYAIVEIHKGENVLISSPTGS 61
M +++ +EYSDEEIY IL+ V+EWFKRK+K+FTPPQRYAI EIH+G+NVLI SPTGS
Sbjct: 1 MGRVEYLKKEYSDEEIYEILEKPVKEWFKRKYKTFTPPQRYAIKEIHEGKNVLICSPTGS 60
Query: 62 GKTLSAFLAIISELISLGRRGKLEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQEL 121
GKTLSAFLA I+ELI L KLED+IY +YVSPLRALNNDI RNL+EPL+EI ++++E+
Sbjct: 61 GKTLSAFLAGINELIKLSMENKLEDRIYILYVSPLRALNNDIERNLKEPLKEIYDVAKEI 120
Query: 122 NEEIPEIRVAVRTSDTSSYEKSKMLKMPPHILITTPESLAIALNAPRFREKLRDVKWVIV 181
E+ EIRVAVRTSDT+S +K +MLK PPHILITTPESLAIALN+P+F + L +K+VIV
Sbjct: 121 GIELDEIRVAVRTSDTTSSQKQRMLKKPPHILITTPESLAIALNSPKFSQLLSGIKYVIV 180
Query: 182 DEVHALAENKRGSHLALTLERLRELTKRDFVRIGLSATIHPLEEVAKFVFGFSDDGKPRP 241
DE+HAL NKRG HL+L+LERL + +F+RIGLSATIHPL EVAKF+ G R
Sbjct: 181 DEIHALT-NKRGVHLSLSLERLNRIA--NFIRIGLSATIHPLTEVAKFLV-----GNGRD 232
Query: 242 GLIVDVSFAKKTKITVESVVEDLVYTPANVLNEALYRRIGELVRSRKTTLIFTNTRSGAE 301
IVDVS+ K+ +I V S V+D +YTP+ +++ LY + +L+ KTTLIFTNTRS E
Sbjct: 233 CYIVDVSYKKEIEIKVISPVDDFIYTPSEEISKRLYNLLKKLIEEHKTTLIFTNTRSATE 292
Query: 302 RVAYHLKKMFPEWEDKIEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTID 361
RVA++LK++ E K+E HHSSLSRE RLEVEE+LK+GE+++ +SSTSLELG+DIG+ID
Sbjct: 293 RVAFYLKQLGVE---KVETHHSSLSREHRLEVEEKLKKGEIRVCISSTSLELGVDIGSID 349
Query: 362 LVILIGSPKSVNRALQRIGRAGHRLHEVSEGVILALDRDDLVEVTVLAHNARKRKLDRIK 421
LVIL+GSPKSV+RALQRIGR+GHRLHE S+G+I+ DRDDLVE VLA++A+ K+DRI
Sbjct: 350 LVILLGSPKSVSRALQRIGRSGHRLHEKSKGIIIPFDRDDLVENVVLAYDAKIGKIDRIH 409
Query: 422 IPKNPLDVLVQHLLGMALERVWEVEEAYKVVRRAYPYHDLPFEDFINVLKYLAGEFSGLE 481
IPKN LDVL QHL+GMALE+VW+V+EAY ++++AYPY DL +DF++VL YLAG G+E
Sbjct: 410 IPKNCLDVLAQHLVGMALEKVWDVDEAYNLIKKAYPYKDLSKKDFLDVLNYLAG---GIE 466
Query: 482 ERKVYAKIWLENGKFGKRGKMTRAIYYMNTGTIPDEAKIDVFTMDKKYIGTVEEEFAERL 541
E+ VYAKIWL++ KFGKRGK RAIYYMN GTIPDE +DV D KY+G VEEEFAE+L
Sbjct: 467 EKNVYAKIWLKDNKFGKRGKSVRAIYYMNVGTIPDETAVDVIA-DGKYVGEVEEEFAEKL 525
Query: 542 IPGDIFVLAGRTYEFVKSRGNKIYVIPREGVKPTIPSWFSEMLPLSFDLALDIQKFRREV 601
+ GDIFVL G+TY+++ RGNKI V KPTIP+WFSE LPL++DLALDI+KFR+EV
Sbjct: 526 MKGDIFVLGGKTYKYLGGRGNKIRVKEVFDEKPTIPAWFSEQLPLAYDLALDIEKFRKEV 585
Query: 602 KSLLNDEDAELKLMEKYGIDEITAKAIISYFREQANYSVIPDDETVLVEIVKEGNVVKYF 661
S D E ++ EKY IDE TAKAI +Y EQ ++++PDDE VL+E E Y
Sbjct: 586 LS----SDIE-EIREKYDIDEKTAKAIKNYMDEQNKFAIVPDDEKVLIENFDEEKRRYYI 640
Query: 662 FHTLIGRRANDALSRAFAYLISKRKRCNVGMAITDNGFMLKVPRDKELSQEEVLELFQVE 721
FH + GRRAN+AL+RAFA ISK K+CNV +++ D GF L +P+++++ + ++ ELF ++
Sbjct: 641 FHFVAGRRANEALARAFANYISKIKKCNVRISVNDYGFALILPKNRKIKRADITELFNLD 700
Query: 722 NLRETLKRALDNTELLKRRFRHVANRGLLVLRRYMGRKKSLSRQQMNAQTLLNFLKRNYP 781
++ +K +++ +E+LKRRFRHVA RG ++LRRYM RK S+ RQQ NA+ LL + K
Sbjct: 701 VVK-NVKESIERSEILKRRFRHVATRGFMILRRYMNRKISVDRQQFNAEMLLKYCKE--V 757
Query: 782 EFPLLKEVYREILEDKMDIENAELFLKWIKEGKVKIVVEEHSYPSPFAFNLEVVGASDVV 841
PL +E REILED +DI+NA + + IK K+ + E PSPFAFNL V +SDV+
Sbjct: 758 NHPLYRETLREILEDSLDIDNALDYFEKIKRRKIYYL--ELPSPSPFAFNLVVSASSDVI 815
Query: 842 LMEDRRELIRQLHQKIMAIIASQGQ 866
MED++++I +LH+K+M I+ +G+
Sbjct: 816 FMEDKKKMIAELHKKVMEFISMKGK 840
>gi|11500031 large helicase-related protein (lhr-2) [Archaeoglobus fulgidus]
Length = 862
Score = 968 bits (2474), Expect = 0.0
Identities = 493/857 (57%), Positives = 640/857 (74%), Gaps = 10/857 (1%)
Query: 10 REYSDEEIYSILDPIVREWFKRKFKSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFL 69
+ YSDEEI + L P+VREWF K+ FTPPQ+YAIVE KG NVLI+SPTGSGKTL+AFL
Sbjct: 6 KPYSDEEILNSLHPLVREWFLSKYSEFTPPQKYAIVEAFKGRNVLITSPTGSGKTLAAFL 65
Query: 70 AIISELISLGRRGKLEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIR 129
A IS L+ +G+LED++Y VYVSPL+ALNNDIR+NLEEPL+EI L+++ ++ +IR
Sbjct: 66 AAISMLVEKAEKGELEDRVYVVYVSPLKALNNDIRKNLEEPLEEIYALAEKKGIKLQKIR 125
Query: 130 VAVRTSDTSSYEKSKMLKMPPHILITTPESLAIALNAPRFREKLRDVKWVIVDEVHALAE 189
AVRT DT + EK K + PPHILITTPE+LAI L +P+F + L +V+++IVDE+HA+AE
Sbjct: 126 AAVRTGDTDAAEKQKQARKPPHILITTPETLAIVLCSPKFSKSLTNVRFLIVDEIHAIAE 185
Query: 190 NKRGSHLALTLERLRELTKRDFVRIGLSATIHPLEEVAKFVFGFSDDGKPRPGLIVDVSF 249
NKRG HL L++ERL+ + + + VRIGLSATI PLEE+A+F+ G+ + G+ R +I DV+F
Sbjct: 186 NKRGVHLTLSMERLQRIQEGEMVRIGLSATISPLEEIARFLVGY-NYGEERDCVIADVTF 244
Query: 250 AKKTKITVESVVEDLVYTPANVLNEALYRRIGELVRSRKTTLIFTNTRSGAERVAYHLKK 309
K I V S + D A +++ LY + E V+S KTTLIFTNTRS ERV YHLKK
Sbjct: 245 EKPMDIKVVSPINDFFSASAEEISDRLYDLLAEYVKSSKTTLIFTNTRSATERVVYHLKK 304
Query: 310 MFPEWEDKIEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILIGSP 369
++ I+AHHSSLS+EVRLEVE LK GEL+ +VSSTSLELGIDIG IDLVIL+GSP
Sbjct: 305 RLKDF--PIKAHHSSLSKEVRLEVENELKNGELRCVVSSTSLELGIDIGYIDLVILLGSP 362
Query: 370 KSVNRALQRIGRAGHRLHEVSEGVILALDRDDLVEVTVLAHNARKRKLDRIKIPKNPLDV 429
KS+NRALQRIGR+GHRLHEVS G I+ +D+DDLVE TVLA AR+R+LDR+KIP+ LDV
Sbjct: 363 KSINRALQRIGRSGHRLHEVSVGRIVVVDQDDLVECTVLAKEARERRLDRVKIPRKCLDV 422
Query: 430 LVQHLLGMALERVWEVEEAYKVVRRAYPYHDLPFEDFINVLKYLAGEFSGLEERKVYAKI 489
L QH++GMA+E+VW V+EA ++R AYPY +L E+F++VL+YL+G FS LE++KVYAKI
Sbjct: 423 LCQHVVGMAIEKVWSVDEALALIRNAYPYRELTREEFLSVLRYLSGNFSELEKKKVYAKI 482
Query: 490 WL--ENGKFGKRGKMTRAIYYMNTGTIPDEAKIDVFTMDKKYIGTVEEEFAERLIPGDIF 547
W E G FG+RGKM R IYY+NTGTIPDE + V T D K +G VEEEFAE L+PGDIF
Sbjct: 483 WFDEEEGVFGRRGKMIRPIYYLNTGTIPDEVAVKVITKDGKRVGKVEEEFAENLLPGDIF 542
Query: 548 VLAGRTYEFVKSRGNKIYVIPREGVKPTIPSWFSEMLPLSFDLALDIQKFRREVKSLLND 607
VLAG+T+ F+K++G I V EG KPT+PSWFSE LPLS+DLA I+KFR ++ +L
Sbjct: 543 VLAGKTFRFLKAKGMSIIVEEVEGEKPTVPSWFSEQLPLSYDLAERIRKFRGWMEEMLEK 602
Query: 608 EDAE---LKLMEKYGIDEITAKAIISYFREQANYSVIPDDETVLVEIVKEGNVVKYFFHT 664
+ E LME + I+ A AI YF EQ +S IP D ++VE E YFFHT
Sbjct: 603 KSREEIIAILMENFEIERNAANAIYRYFMEQKLFSEIPTDSKLVVE-KYEAERNYYFFHT 661
Query: 665 LIGRRANDALSRAFAYLISKRKRCNVGMAITDNGFMLKVPRDKELSQEEVLELFQVENLR 724
LIGRRAN A++R FAY K CNV M I DNGF+L +P K LS E+ LF +
Sbjct: 662 LIGRRANSAIARVFAYRAGLIKNCNVQMGINDNGFVLILPSYKRLSDAEIEGLFVIPEFE 721
Query: 725 ETLKRALDNTELLKRRFRHVANRGLLVLRRYMGRKKSLSRQQMNAQTLLNFLKRNYPEFP 784
L++ALD TE+L+RRFRHVA R L++LR YMGR+KS+ RQQ +A ++L+FL+R YP+FP
Sbjct: 722 GHLRKALDRTEILRRRFRHVAVRSLMILRNYMGREKSVWRQQFSADSILSFLRRYYPDFP 781
Query: 785 LLKEVYREILEDKMDIENAELFLKWIKEGKVKIVVEEHSYPSPFAFNLEVVGASDVVLME 844
+LKE YREI+ED M+IE+A FL + ++++V+ YPSPFAFN+ ++G DVVLME
Sbjct: 782 VLKETYREIMEDAMNIEDAMEFLAKVGR-EMELVIVRTPYPSPFAFNMYLLGEQDVVLME 840
Query: 845 DRRELIRQLHQKIMAII 861
DRR+++++LH+K+M +I
Sbjct: 841 DRRKILKELHEKVMGVI 857
>pir||G71051 probable ATP-dependent helicase LHR - Pyrococcus horikoshii
>gi|3257526|dbj|BAA30209.1| (AP000005) 1352aa long
hypothetical ATP-dependent helicase LHR [Pyrococcus
horikoshii]
Length = 1352
Score = 931 bits (2381), Expect = 0.0
Identities = 453/515 (87%), Positives = 492/515 (94%)
Query: 347 SSTSLELGIDIGTIDLVILIGSPKSVNRALQRIGRAGHRLHEVSEGVILALDRDDLVEVT 406
SSTSLELGIDIGTIDLV+L+GSPKSVNRALQRIGRAGHRLHEVS G+ILALDRDDLVEVT
Sbjct: 822 SSTSLELGIDIGTIDLVVLVGSPKSVNRALQRIGRAGHRLHEVSRGIILALDRDDLVEVT 881
Query: 407 VLAHNARKRKLDRIKIPKNPLDVLVQHLLGMALERVWEVEEAYKVVRRAYPYHDLPFEDF 466
VLAHNAR RKLDRIKIPKNPLDVLVQH+LGMALE+VWE+EEAY+VVRRAYPYH+LPF DF
Sbjct: 882 VLAHNARNRKLDRIKIPKNPLDVLVQHILGMALEKVWEIEEAYRVVRRAYPYHELPFSDF 941
Query: 467 INVLKYLAGEFSGLEERKVYAKIWLENGKFGKRGKMTRAIYYMNTGTIPDEAKIDVFTMD 526
+NVLKYLAGE+SGLEE++VYAKIWLENGKFG+RGKMTRAIYYMNTGTIPDEAKIDVFT+D
Sbjct: 942 MNVLKYLAGEYSGLEEKRVYAKIWLENGKFGRRGKMTRAIYYMNTGTIPDEAKIDVFTLD 1001
Query: 527 KKYIGTVEEEFAERLIPGDIFVLAGRTYEFVKSRGNKIYVIPREGVKPTIPSWFSEMLPL 586
KKYIGTVEEEFAERL+PGDIFVLAGRTYEFVKSRGNKIYVIPREG KPTIPSWFSEMLPL
Sbjct: 1002 KKYIGTVEEEFAERLMPGDIFVLAGRTYEFVKSRGNKIYVIPREGAKPTIPSWFSEMLPL 1061
Query: 587 SFDLALDIQKFRREVKSLLNDEDAELKLMEKYGIDEITAKAIISYFREQANYSVIPDDET 646
SFDLA+DIQ+FR EVK LL + AE LM+KYGID +TAKAIISYFREQA YS+IPDDET
Sbjct: 1062 SFDLAIDIQRFRGEVKKLLTSKRAESLLMKKYGIDNVTAKAIISYFREQAKYSIIPDDET 1121
Query: 647 VLVEIVKEGNVVKYFFHTLIGRRANDALSRAFAYLISKRKRCNVGMAITDNGFMLKVPRD 706
VLVEIV+EGNV KYFFHTLIGRRANDALSRAFAY+ISK+K+CNVG+AITDNGFMLKVP D
Sbjct: 1122 VLVEIVREGNVTKYFFHTLIGRRANDALSRAFAYMISKKKKCNVGIAITDNGFMLKVPVD 1181
Query: 707 KELSQEEVLELFQVENLRETLKRALDNTELLKRRFRHVANRGLLVLRRYMGRKKSLSRQQ 766
KEL + E+LELF VENLRE LKRALDNTELLKRRFRHVANRGLL+LRRYMGR+KSLSRQQ
Sbjct: 1182 KELKEGEILELFYVENLREILKRALDNTELLKRRFRHVANRGLLILRRYMGREKSLSRQQ 1241
Query: 767 MNAQTLLNFLKRNYPEFPLLKEVYREILEDKMDIENAELFLKWIKEGKVKIVVEEHSYPS 826
MNAQTLLNFLK+N+P FPLLKEVYREI+EDKMDIENAELFLKWIKEGK+K+ V EH YPS
Sbjct: 1242 MNAQTLLNFLKKNHPNFPLLKEVYREIMEDKMDIENAELFLKWIKEGKIKVTVREHPYPS 1301
Query: 827 PFAFNLEVVGASDVVLMEDRRELIRQLHQKIMAII 861
PFAFNLEV+GASDVVLMEDRRELI++LH+KIMAII
Sbjct: 1302 PFAFNLEVIGASDVVLMEDRRELIKELHKKIMAII 1336
Score = 592 bits (1509), Expect = e-168
Identities = 291/346 (84%), Positives = 322/346 (92%)
Query: 1 MMSEIKWANREYSDEEIYSILDPIVREWFKRKFKSFTPPQRYAIVEIHKGENVLISSPTG 60
MM ++WA R+Y+D+EIYSILDP+VREWFKRKF SFTPPQRYAIVEIHKGENVLISSPTG
Sbjct: 1 MMGNVRWAKRKYTDDEIYSILDPLVREWFKRKFNSFTPPQRYAIVEIHKGENVLISSPTG 60
Query: 61 SGKTLSAFLAIISELISLGRRGKLEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQE 120
SGKTLSAFLAIISELISLGR+GKLEDKIYCVY+SPLRALNNDIRRNLEEPL+EI+EL+QE
Sbjct: 61 SGKTLSAFLAIISELISLGRKGKLEDKIYCVYISPLRALNNDIRRNLEEPLREIKELAQE 120
Query: 121 LNEEIPEIRVAVRTSDTSSYEKSKMLKMPPHILITTPESLAIALNAPRFREKLRDVKWVI 180
L EEIPEIR+AVRTSDTSSYEKSKM+K PPHILITTPESLAIALNAP+FRE+LRDV+WVI
Sbjct: 121 LGEEIPEIRIAVRTSDTSSYEKSKMVKKPPHILITTPESLAIALNAPKFRERLRDVRWVI 180
Query: 181 VDEVHALAENKRGSHLALTLERLRELTKRDFVRIGLSATIHPLEEVAKFVFGFSDDGKPR 240
VDEVHALAENKRGSHLALTLERLREL RDFVRIGLSATIHPLEEVAKFVFGF+DDG PR
Sbjct: 181 VDEVHALAENKRGSHLALTLERLRELVGRDFVRIGLSATIHPLEEVAKFVFGFNDDGTPR 240
Query: 241 PGLIVDVSFAKKTKITVESVVEDLVYTPANVLNEALYRRIGELVRSRKTTLIFTNTRSGA 300
GLIVDVSFAK+T+I VESVVEDL+YT A L+ ALY R+ EL+R KTTLIFTNTRSGA
Sbjct: 241 SGLIVDVSFAKQTEIKVESVVEDLIYTDAETLSNALYNRLAELIRKHKTTLIFTNTRSGA 300
Query: 301 ERVAYHLKKMFPEWEDKIEAHHSSLSREVRLEVEERLKRGELKIIV 346
ERVA++LKK FPE++ IE HHSSLSREVRL+VEE+LKRGEL+ +V
Sbjct: 301 ERVAFNLKKRFPEFKGLIETHHSSLSREVRLDVEEKLKRGELRAVV 346
>sp|O27830|HELX_METTH PUTATIVE ATP-DEPENDENT HELICASE MTH1802 >gi|7446115|pir||H69107
ATP-dependent helicase - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2622934|gb|AAB86268.1| (AE000934) ATP-dependent
helicase [Methanobacterium thermoautotrophicum]
Length = 862
Score = 872 bits (2229), Expect = 0.0
Identities = 469/864 (54%), Positives = 605/864 (69%), Gaps = 18/864 (2%)
Query: 5 IKWANREYSDEEIYSILDPIVREWFKRKFKSFTPPQRYAIVEIHKGENVLISSPTGSGKT 64
IK R Y+ EI+SIL P V EWF+R F FT QRYAI++IH+G NVL+SSPTGSGKT
Sbjct: 2 IKKQERMYTSGEIHSILHPWVSEWFRRTFDDFTEAQRYAIMDIHRGRNVLVSSPTGSGKT 61
Query: 65 LSAFLAIISELISLGRRGKLEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEE 124
L+AFL+IISEL L G+LED +YC+Y+SPL+AL+NDI RNLEEPL IR+++ +
Sbjct: 62 LTAFLSIISELTRLADDGELEDSVYCIYISPLKALDNDIERNLEEPLSAIRDIAAGEGRD 121
Query: 125 IPEIRVAVRTSDTSSYEKSKMLKMPPHILITTPESLAIALNAPRFREKLRDVKWVIVDEV 184
+ EIR AVRT DT+SYE+S+MLK PPHILITTPE+L+I L AP+FREKL V++VIVDE+
Sbjct: 122 L-EIRKAVRTGDTTSYERSRMLKKPPHILITTPETLSILLVAPKFREKLSTVRYVIVDEI 180
Query: 185 HALAENKRGSHLALTLERLRELTKRDFVRIGLSATIHPLEEVAKFVFGFSDDGKPRPGLI 244
H+LA+NKRG HL+L+LERL+ L DF RIGLSAT+HPLE VA+F+ G+S G R LI
Sbjct: 181 HSLADNKRGVHLSLSLERLQHLVG-DFTRIGLSATVHPLERVARFLVGYSY-GSERECLI 238
Query: 245 VDVSFAKKTKITVESVVEDLVYTPANVLNEALYRRIGELVRSRKTTLIFTNTRSGAERVA 304
VDVS+ K+ I + V+D+V + ALY + +L+ +TTLIFTNTRSG E V
Sbjct: 239 VDVSYLKELDIDLICPVDDIVAADPEEIGNALYDILHDLIEDHRTTLIFTNTRSGTESVV 298
Query: 305 YHLKKMFPEW--EDKIEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDL 362
Y+LK FPE + I AHHSSLSRE+RLE EE+LKRGELK +VSSTSLELGIDIG IDL
Sbjct: 299 YNLKSRFPESYSDSNIMAHHSSLSREIRLETEEKLKRGELKAVVSSTSLELGIDIGYIDL 358
Query: 363 VILIGSPKSVNRALQRIGRAGHRLHEVSEGVILALDRDDLVEVTVLAHNARKRKLDRIKI 422
V+L+ SPKSV+RALQRIGR+GH+LH+ S+G I+ +DRDDLVE +++ NA + K+D IK+
Sbjct: 359 VVLLSSPKSVSRALQRIGRSGHQLHQRSKGRIVVVDRDDLVECSLILKNALEGKIDSIKV 418
Query: 423 PKNPLDVLVQHLLGMALERVWEVEEAYKVVRRAYPYHDLPFEDFINVLKYLAGEFSGLEE 482
P+N LDVL QH+ GMA+E W+++ A V+R +Y Y +L ED+++VL YLAGE+ LEE
Sbjct: 419 PENCLDVLAQHIYGMAIENPWDIDHALAVIRNSYCYRNLSREDYLSVLSYLAGEYVELEE 478
Query: 483 RKVYAKIWLENGK--FGKRGKMTRAIYYMNTGTIPDEAKIDVFTMDKKYIGTVEEEFAER 540
R VYAKIW++ K FGKRGK+ R +Y N GTIPD + V K +G +EE+F E+
Sbjct: 479 RYVYAKIWVDYDKNQFGKRGKLARMLYSTNIGTIPDRSAA-VVKCGGKVVGRIEEDFMEK 537
Query: 541 LIPGDIFVLAGRTYEFVKSRGNKIYVIPREGVKPTIPSWFSEMLPLSFDLALDIQKFRRE 600
L GD FVL GR Y F +RG + V P G PTIPSWFSE LPLSFDLALDIQ+FR
Sbjct: 538 LRKGDTFVLGGRIYRFNYARGMTVNVTPASG-PPTIPSWFSEQLPLSFDLALDIQRFRDI 596
Query: 601 VKSLL-----NDEDAELKLMEKYGIDEITAKAIISYFREQANYSVIPDDETVLVEIVKEG 655
+ DE E +M +DE A +I YFREQ Y+ IP +LVE
Sbjct: 597 MDGKFQYGRSRDEIMEF-IMSYLHVDERAASSIYEYFREQYLYAGIPSIRRMLVEYYTGF 655
Query: 656 NVVKYF-FHTLIGRRANDALSRAFAYLISKRKRCNVGMAITDNGFMLKVPRDKELSQEEV 714
K+ FH+L GRR NDA+SRA AY+I++R R +V ++++DNGF L + ++ E
Sbjct: 656 GGRKFIVFHSLFGRRVNDAISRAVAYVIARRYRRDVMISVSDNGFYLS--SEGKMGGLEA 713
Query: 715 LELFQVENLRETLKRALDNTELLKRRFRHVANRGLLVLRRYMGRKKSLSRQQMNAQTLLN 774
+ ENLR LK+ALD TE L RFRH A R L++LRRY G +KS+ RQQ+ + LL
Sbjct: 714 FRELEPENLRNVLKKALDRTETLASRFRHCAGRALMILRRYRGEEKSVGRQQVRGKILLK 773
Query: 775 FLKRNYPEFPLLKEVYREILEDKMDIENAELFLKWIKEGKVKIVVEEHSYPSPFAFNLEV 834
F+ +FP+L+E RE++ED MDIENA L+WI++G ++I PSPFAFNL
Sbjct: 774 FVSELDDKFPILEEARREVMEDYMDIENAIRVLEWIRDGDMEIKQINTRIPSPFAFNLVA 833
Query: 835 VGASDVVLMEDRRELIRQLHQKIM 858
G DV+ EDR E IR++HQ I+
Sbjct: 834 QGYLDVLKYEDRIEFIRRMHQAII 857
>pir||C72521 hypothetical protein APE2144 - Aeropyrum pernix (strain K1)
>gi|5105843|dbj|BAA81155.1| (AP000063) 880aa long
hypothetical protein [Aeropyrum pernix]
Length = 880
Score = 868 bits (2218), Expect = 0.0
Identities = 463/860 (53%), Positives = 613/860 (70%), Gaps = 21/860 (2%)
Query: 20 ILDPIVREWFKRKFKSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAIISELISLG 79
+L P V EWF+ + SFT PQR AI + +G++VLI+SPTG+GKTL+AFL +I E++ L
Sbjct: 1 MLRPYVAEWFRSTYGSFTEPQRQAIPLVKQGKSVLITSPTGTGKTLAAFLGVIDEILFLM 60
Query: 80 RRGKLEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRTSDTSS 139
E I VYVSPLRALNNDIRRNLEEPL+ I E ++E+ E P ++VAVRTSDT+
Sbjct: 61 ENRWEEKGILAVYVSPLRALNNDIRRNLEEPLRGIEEKAREMGLEPPRVKVAVRTSDTTP 120
Query: 140 YEKSKMLKMPPHILITTPESLAIALNAPRFREKLRDVKWVIVDEVHALAENKRGSHLALT 199
YEK KM+K PPHILITTPESLA AL AP+FRE+L VKWV++DE+H LA NKRG+HL ++
Sbjct: 121 YEKQKMVKDPPHILITTPESLAAALAAPKFRERLSTVKWVVLDEIHELASNKRGAHLMVS 180
Query: 200 LERLRELTK----RDFVRIGLSATIHPLEEVAKFVFGFSDDGKPRPGLIVDVSFAKKTKI 255
+ERL EL + + RIGLSATI PL+ VA F+ GF D+G+PR IVD FAK I
Sbjct: 181 VERLEELVREAGGKPLRRIGLSATIAPLDVVANFLGGFDDEGRPREVHIVDARFAKPIDI 240
Query: 256 TVESVVEDLVYTPANVLNEALYRRIGELVRSRKTTLIFTNTRSGAERVAYHLKKMFPE-- 313
V + DL+ P + +NEA+YR+I ELV+ +TTLIFTNTRS ERV + LK++ +
Sbjct: 241 KVITPDVDLLRDPPDKINEAIYRKIAELVKQHRTTLIFTNTRSATERVVHKLKQILVKEG 300
Query: 314 --WEDKIEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILIGSPKS 371
ED+IEAHHSSLSR +RL+VEERLKRGELK++VSSTSLELGIDIG IDLVIL+ SPKS
Sbjct: 301 IASEDQIEAHHSSLSRNLRLDVEERLKRGELKVVVSSTSLELGIDIGYIDLVILLSSPKS 360
Query: 372 VNRALQRIGRAGHRLHEVSEGVILALDRDDLVEVTVLAHNARKRKLDRIKIPKNPLDVLV 431
V+R LQR+GRAGHR+ +VS+G ++ +DRDDLVE +VLA A K+ +DR++IP PLDVL
Sbjct: 361 VSRLLQRVGRAGHRIRDVSKGRLIVVDRDDLVECSVLADCAMKKFIDRVRIPMKPLDVLA 420
Query: 432 QHLLGMALERVWEVEEAYKVVRRAYPYHDLPFEDFINVLKYLAGEFSGLEERKVYAKIWL 491
QH++GM++E+ W +E+AY+VV+RAY + DL FE+F++V+++LAG+ GLE VY+KIWL
Sbjct: 421 QHIVGMSIEKKWRLEDAYRVVKRAYNFKDLSFEEFMSVVRFLAGK-HGLEGEGVYSKIWL 479
Query: 492 --ENGKFGKRGKMTRAIYYMNTGTIPDEAKIDVFTMDKKYIGTVEEEFAERLIPGDIFVL 549
E G FG++ K R IY +N G IPDE KI V+T D KY+G +EEEF E L+PGD+FVL
Sbjct: 480 DEEEGLFGRK-KSARMIYLLNVGVIPDETKIRVYTRDGKYVGDLEEEFVEILVPGDVFVL 538
Query: 550 AGRTYEFVKSRGNKIYVIPREGVKPTIPSWFSEMLPLSFDLALDIQKFRREVKSLL--ND 607
GRTY F+KS G ++ V + +PT+PSWFSEMLPLSFD AL + +FRR +L N
Sbjct: 539 GGRTYRFLKSEGLRVIVERADDARPTVPSWFSEMLPLSFDSALKVGEFRRVFSALASSNP 598
Query: 608 EDAELKLMEKYGIDEITAKAIISYFREQANY-SVIPDDETVLVEIVKEGNVVKYFFHTLI 666
A KL+++Y ++E A I+ Y EQ Y V+P D+ VL+E + FHTL
Sbjct: 599 RAAVEKLVKEYYLEERAAATIVEYILEQLGYIGVVPSDKLVLIEYFPYEDGWGIVFHTLF 658
Query: 667 GRRANDALSRAFAYLISKRKRCNVGMAITDNGFMLKVPR----DKELSQEEVLELFQVEN 722
GRR NDALSRA+A +S+R V +A+TDNGFML V D L E+++ EN
Sbjct: 659 GRRVNDALSRAYAVALSRRIGLPVRVAVTDNGFMLTVSEAGKPDASL-LEKLIRDVTPEN 717
Query: 723 LRETLKRALDNTELLKRRFRHVANRGLLVLRRYMGRKKSLSRQQMNAQTLLNFLKRNYPE 782
+R L+ A+ TEL+KRRF+HVA R +VLRRY G++ S R Q+N+Q LL +
Sbjct: 718 IRGILEEAISRTELMKRRFKHVAARMFIVLRRYKGKEVSPERLQLNSQKLLEVFLEEMKD 777
Query: 783 FPLLKEVYREILEDKMDIENAELFLKWIKEGKVKIVVE-EHSYPSPFAFNLEVVGASDVV 841
P ++E +REILED MDI A L+WI++G+++IV++ YPSP A ++ V G SDVV
Sbjct: 778 SPPIRETFREILEDYMDIGAAGKVLEWIRKGEIEIVIKGPLPYPSPMAHSIVVRGYSDVV 837
Query: 842 LMEDRRELIRQLHQKIMAII 861
LMEDRR+++ L +K++ I
Sbjct: 838 LMEDRRKMLMILREKVLEYI 857
>sp|P95949|HELX_SULSO PUTATIVE ATP-DEPENDENT HELICASE C04010 >gi|7446117|pir||S75377
probable helicase LHR - Sulfolobus solfataricus
>gi|1707782|emb|CAA69580.1| (Y08257) ATP-dependent
helicase [Sulfolobus solfataricus]
Length = 875
Score = 841 bits (2150), Expect = 0.0
Identities = 442/869 (50%), Positives = 615/869 (69%), Gaps = 25/869 (2%)
Query: 12 YSDEEIYSILDPIVREWFKRKFKSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAI 71
YSDEEIY++L P V +WF++K+ +FTPPQR AI I + NVL+SSPTGSGKTL+AFL I
Sbjct: 7 YSDEEIYNLLRPYVAKWFRQKYTTFTPPQRAAIPLIKQNYNVLVSSPTGSGKTLAAFLGI 66
Query: 72 ISELISLGRRGKLEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVA 131
+ L LG +LEDK+Y +Y+SPLRALNND++RNL EPL E+R++ N ++P++RV
Sbjct: 67 LDSLFELGDNNELEDKVYAIYISPLRALNNDMQRNLLEPLNELRQV----NSKLPDVRVG 122
Query: 132 VRTSDTSSYEKSKMLKMPPHILITTPESLAIALNAPRFREKLRDVKWVIVDEVHALAENK 191
+RTSDT+ YEK KMLK PPHILITTPES I++ +P+F +KL DVKW+IVDE+H LA +K
Sbjct: 123 IRTSDTTPYEKQKMLKKPPHILITTPESFGISITSPKFSQKLTDVKWIIVDEIHELANSK 182
Query: 192 RGSHLALTLERLREL-TKRDFVRIGLSATIHPLEEVAKFVFGFSDDGKPRPGLIVDVSFA 250
RG++L+ LE R L TK++FVRIGLSAT+ PLEEVA+F+ G K R IVD F
Sbjct: 183 RGAYLSAMLELFRNLITKKEFVRIGLSATVSPLEEVAQFLVG-----KDREYRIVDARFV 237
Query: 251 KKTKITVESVVEDLVYTPANVLNEALYRRIGELVRSRKTTLIFTNTRSGAERVAYHLKKM 310
K I V S V+DLV++ + +++ +Y+ I V+ +TTLIFTNTR ERVAY L+K+
Sbjct: 238 KPVDIKVISPVKDLVHSSESEVDKGIYKTILNEVKKHRTTLIFTNTRHATERVAYKLRKL 297
Query: 311 FPEWE----DKIEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILI 366
+ D IEAHHSSLSR+VRL+VEE+LK+G LK++VSSTSLELGIDIG IDLVIL+
Sbjct: 298 AENEKVFDVDAIEAHHSSLSRDVRLDVEEKLKKGILKVVVSSTSLELGIDIGYIDLVILL 357
Query: 367 GSPKSVNRALQRIGRAGHRLHEVSEGVILALDRDDLVEVTVLAHNARKRKLDRIKIPKNP 426
SPKSV+R LQRIGRAGH + +S+G ++ +DRDDLVE +VLA AR RK+D I IPKNP
Sbjct: 358 SSPKSVSRLLQRIGRAGHHIRSISKGRVIVVDRDDLVECSVLAKLARDRKIDSIHIPKNP 417
Query: 427 LDVLVQHLLGMALERVWEVEEAYKVVRRAYPYHDLPFEDFINVLKYLAGEFSGLEERKVY 486
LDVL Q ++ +L + ++ +K++RR+Y + DL D+ VL+YL+G+F G+E + VY
Sbjct: 418 LDVLSQIIVSASLISPIDRDDLFKILRRSYNFSDLSESDYSLVLRYLSGDFFGVELKNVY 477
Query: 487 AKIWLENGKFGKRGKMTRAIYYMNTGTIPDEAKIDVFTMDKKYIGTVEEEFAERLIPGDI 546
AKI ++ K K +R I+Y N+GTIPDEA I V T + +Y+G +EEEF E L PGDI
Sbjct: 478 AKIRIKEEKIIYPKKGSRLIFYTNSGTIPDEAMISVVTENNRYVGNLEEEFVEILSPGDI 537
Query: 547 FVLAGRTYEFVKSRGNKIYVIPREGVKPTIPSWFSEMLPLSFDLALDIQKFRREVKSLLN 606
FVL+GRTYEF+ S+G+K+ V G +PT+PSWFSEMLPL+++ AL+I KFRRE+ ++
Sbjct: 538 FVLSGRTYEFIGSKGSKVIVKEAMGQRPTVPSWFSEMLPLAYESALEIGKFRREIAEMIK 597
Query: 607 DEDAELKLME----KYGIDEITAKAIISYFREQANYS--VIPDDETVLVEIV-KEGNVVK 659
+++E +Y ID+ + +I +Y EQ ++ +P D +L+EI E +
Sbjct: 598 KGVTHNEIIESISKEYEIDKHASMSIYTYILEQYLFTNGKVPSDNLILIEIYDDEEGIRN 657
Query: 660 YFFHTLIGRRANDALSRAFAYLISKRKRCNVGMAITDNGFMLKVPRDK--ELSQEEVLEL 717
Y FH L GRRA DALSRAFAY++S+ +V +++TDNGF L V RD + + + + E
Sbjct: 658 YIFHALYGRRALDALSRAFAYVVSEELDTDVRVSVTDNGFALSVKRDVPFDYNIKSLFEK 717
Query: 718 FQVENLRETLKRALDNTELLKRRFRHVANRGLLVLRRYMGRKKSLSRQQMNAQTLLNFLK 777
+N+ + + RA+ TE+LKRRFRH A R ++LRRY GR+ +L R+++N++ LL +
Sbjct: 718 ITPDNVYDIVTRAVMRTEMLKRRFRHCAERSFMILRRYKGRETNLERRELNSEILLKAI- 776
Query: 778 RNYPEFPLLKEVYREILEDKMDIENAELFLKWIKEGKVKI-VVEEHSYPSPFAFNLEVVG 836
R FP++KE REILED MDI A+ LK I ++K+ V + PSPF+ ++ + G
Sbjct: 777 REIGNFPVMKETIREILEDHMDILRAKEILKKIASQEIKVDVFGPTNIPSPFSHSIILKG 836
Query: 837 ASDVVLMEDRRELIRQLHQKIMAIIASQG 865
SDVVL EDRREL+++LH++++ + +G
Sbjct: 837 HSDVVLAEDRRELLKKLHERVVEFLRQKG 865
>gb|AAK40467.1| ATP-dependent helicase [Sulfolobus solfataricus]
Length = 875
Score = 841 bits (2150), Expect = 0.0
Identities = 442/869 (50%), Positives = 615/869 (69%), Gaps = 25/869 (2%)
Query: 12 YSDEEIYSILDPIVREWFKRKFKSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAI 71
YSDEEIY++L P V +WF++K+ +FTPPQR AI I + NVL+SSPTGSGKTL+AFL I
Sbjct: 7 YSDEEIYNLLRPYVAKWFRQKYTTFTPPQRAAIPLIKQNYNVLVSSPTGSGKTLAAFLGI 66
Query: 72 ISELISLGRRGKLEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVA 131
+ L LG +LEDK+Y +Y+SPLRALNND++RNL EPL E+R++ N ++P++RV
Sbjct: 67 LDSLFELGDNNELEDKVYAIYISPLRALNNDMQRNLLEPLNELRQV----NSKLPDVRVG 122
Query: 132 VRTSDTSSYEKSKMLKMPPHILITTPESLAIALNAPRFREKLRDVKWVIVDEVHALAENK 191
+RTSDT+ YEK KMLK PPHILITTPES I++ +P+F +KL DVKW+IVDE+H LA +K
Sbjct: 123 IRTSDTTPYEKQKMLKKPPHILITTPESFGISITSPKFSQKLTDVKWIIVDEIHELANSK 182
Query: 192 RGSHLALTLERLREL-TKRDFVRIGLSATIHPLEEVAKFVFGFSDDGKPRPGLIVDVSFA 250
RG++L+ LE R L TK++FVRIGLSAT+ PLEEVA+F+ G K R IVD F
Sbjct: 183 RGAYLSAMLELFRNLITKKEFVRIGLSATVSPLEEVAQFLVG-----KDREYRIVDARFV 237
Query: 251 KKTKITVESVVEDLVYTPANVLNEALYRRIGELVRSRKTTLIFTNTRSGAERVAYHLKKM 310
K I V S V+DLV++ + +++ +Y+ I V+ +TTLIFTNTR ERVAY L+K+
Sbjct: 238 KPVDIKVISPVKDLVHSSESEVDKGIYKTILNEVKKHRTTLIFTNTRHATERVAYKLRKL 297
Query: 311 FPEWE----DKIEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILI 366
+ D IEAHHSSLSR+VRL+VEE+LK+G LK++VSSTSLELGIDIG IDLVIL+
Sbjct: 298 AENEKVFDVDAIEAHHSSLSRDVRLDVEEKLKKGILKVVVSSTSLELGIDIGYIDLVILL 357
Query: 367 GSPKSVNRALQRIGRAGHRLHEVSEGVILALDRDDLVEVTVLAHNARKRKLDRIKIPKNP 426
SPKSV+R LQRIGRAGH + +S+G ++ +DRDDLVE +VLA AR RK+D I IPKNP
Sbjct: 358 SSPKSVSRLLQRIGRAGHHIRSISKGRVIVVDRDDLVECSVLAKLARDRKIDSIHIPKNP 417
Query: 427 LDVLVQHLLGMALERVWEVEEAYKVVRRAYPYHDLPFEDFINVLKYLAGEFSGLEERKVY 486
LDVL Q ++ +L + ++ +K++RR+Y + DL D+ VL+YL+G+F G+E + VY
Sbjct: 418 LDVLSQIIVSASLISPIDRDDLFKILRRSYNFSDLSESDYSLVLRYLSGDFFGVELKNVY 477
Query: 487 AKIWLENGKFGKRGKMTRAIYYMNTGTIPDEAKIDVFTMDKKYIGTVEEEFAERLIPGDI 546
AKI ++ K K +R I+Y N+GTIPDEA I V T + +Y+G +EEEF E L PGDI
Sbjct: 478 AKIRIKEEKIIYPKKGSRLIFYTNSGTIPDEAMISVVTENNRYVGNLEEEFVEILSPGDI 537
Query: 547 FVLAGRTYEFVKSRGNKIYVIPREGVKPTIPSWFSEMLPLSFDLALDIQKFRREVKSLLN 606
FVL+GRTYEF+ S+G+K+ V G +PT+PSWFSEMLPL+++ AL+I KFRRE+ ++
Sbjct: 538 FVLSGRTYEFIGSKGSKVIVKEAMGQRPTVPSWFSEMLPLAYESALEIGKFRREIAEMIK 597
Query: 607 DEDAELKLME----KYGIDEITAKAIISYFREQANYS--VIPDDETVLVEIV-KEGNVVK 659
+++E +Y ID+ + +I +Y EQ ++ +P D +L+EI E +
Sbjct: 598 KGVTHNEIIESISKEYEIDKHASMSIYTYILEQYLFTNGKVPSDNLILIEIYDDEEGIRN 657
Query: 660 YFFHTLIGRRANDALSRAFAYLISKRKRCNVGMAITDNGFMLKVPRDK--ELSQEEVLEL 717
Y FH L GRRA DALSRAFAY++S+ +V +++TDNGF L V RD + + + + E
Sbjct: 658 YIFHALYGRRALDALSRAFAYVVSEELDTDVRVSVTDNGFALSVKRDVPFDYNIKSLFEK 717
Query: 718 FQVENLRETLKRALDNTELLKRRFRHVANRGLLVLRRYMGRKKSLSRQQMNAQTLLNFLK 777
+N+ + + RA+ TE+LKRRFRH A R ++LRRY GR+ +L R+++N++ LL +
Sbjct: 718 ITPDNVYDIVTRAVMRTEMLKRRFRHCAERSFMILRRYKGRETNLERRELNSEILLKAI- 776
Query: 778 RNYPEFPLLKEVYREILEDKMDIENAELFLKWIKEGKVKI-VVEEHSYPSPFAFNLEVVG 836
R FP++KE REILED MDI A+ LK I ++K+ V + PSPF+ ++ + G
Sbjct: 777 REIGNFPVMKETIREILEDHMDILRAKEILKKIASQEIKVDVFGPTNIPSPFSHSIILKG 836
Query: 837 ASDVVLMEDRRELIRQLHQKIMAIIASQG 865
SDVVL EDRREL+++LH++++ + +G
Sbjct: 837 HSDVVLAEDRRELLKKLHERVVEFLRQKG 865
>emb|CAC11727.1| (AL445064) hypothetical protein [Thermoplasma acidophilum]
Length = 1690
Score = 764 bits (1952), Expect = 0.0
Identities = 398/853 (46%), Positives = 572/853 (66%), Gaps = 17/853 (1%)
Query: 10 REYSDEEIYSILDPIVREWFKRKFKSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFL 69
R + E+ + LD V +WF + S T PQ+YAI IH G NVL+SSPTG+GKT++AFL
Sbjct: 6 RLFRIEDFFPFLDTHVSKWFNSNYSSLTEPQKYAIPLIHSGRNVLVSSPTGTGKTMTAFL 65
Query: 70 AIISELISLGRRGKLEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIR 129
II+EL+SL + G+LED++YCVY+SPL+AL NDI +NL+ PL I + ++P +R
Sbjct: 66 TIINELVSLAKEGRLEDRVYCVYISPLKALANDINKNLKFPLDGIYSIMDSEGIKVPRVR 125
Query: 130 VAVRTSDTSSYEKSKMLKMPPHILITTPESLAIALNAPRFREKLRDVKWVIVDEVHALAE 189
++VR+ DT+ E+ KM++ PPHILITTPES ++AL++P+ RE LR+V++VI+DE+H ++
Sbjct: 126 ISVRSGDTTESERQKMVRKPPHILITTPESFSLALSSPKMRENLRNVRYVIIDEIHEISS 185
Query: 190 NKRGSHLALTLERLRELTKRDFVRIGLSATIHPLEEVAKFVFGFSDDGKPRPGLIVDVSF 249
KRGS L+ LERL L VRIGLSAT P+EE+AK++ GF + K RP IV+V
Sbjct: 186 TKRGSLLSANLERL-NLISPGMVRIGLSATQSPIEEIAKYLVGFEGE-KARPCEIVEVRG 243
Query: 250 AKKTKITVESVVEDLVYTPANVLNEALYRRIGELVRSRKTTLIFTNTRSGAERVAYHLKK 309
K + + V DL V N+ +Y I +LV+ +TTLIFTNTRSG E VA LK
Sbjct: 244 EKHLDLRTITPVPDLTRVSYEVANDRMYDIIADLVKQYRTTLIFTNTRSGTEHVAMRLKS 303
Query: 310 MFPEWEDKIEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILIGSP 369
E +EAHHSS+ ++ RLEVE +LK GEL+ +++STSLELGIDIG IDLVI IGSP
Sbjct: 304 RGIE---SLEAHHSSMGKDQRLEVENKLKNGELRCVITSTSLELGIDIGFIDLVIQIGSP 360
Query: 370 KSVNRALQRIGRAGHRLHEVSEGVILALDRDDLVEVTVLAHNARKRKLDRIKIPKNPLDV 429
KSV++ LQRIGR+GH + E+S+G+ + DDLVE VL A R++DR+ IPKNPLDV
Sbjct: 361 KSVSKGLQRIGRSGHGVDELSKGIFIVFTLDDLVECAVLTKAAYSRQIDRVDIPKNPLDV 420
Query: 430 LVQHLLGMALERVWEVEEAYKVVRRAYPYHDLPFEDFINVLKYLAGEFSGLEERKVYAKI 489
L Q L+GM+LERVW +EEAY ++R +Y +H+L E+F+ + YL+GE LE +Y K+
Sbjct: 421 LAQILVGMSLERVWRIEEAYDLLRNSYTFHELSHEEFMMTMDYLSGE---LESLSIYPKV 477
Query: 490 WL--ENGKFGKRGKMTRAIYYMNTGTIPDEAKIDVFTMDKKYIGTVEEEFAERLIPGDIF 547
WL E G FGK+ + TR IY+MN GTIPDEA K +G + ++F ERL GD+F
Sbjct: 478 WLDREAGTFGKK-RSTRMIYFMNVGTIPDEANYKAINEKGKNVGELSDKFVERLKTGDVF 536
Query: 548 VLAGRTYEFVKSRGNKIYVIPREGVKPTIPSWFSEMLPLSFDLALDIQKFRREVKSLL-N 606
VL RTY F K+ N++YV G+KPT+PSW EMLP S+DL + I +FR + S++ +
Sbjct: 537 VLGARTYIFEKTVRNRVYVRSVTGMKPTVPSWTGEMLPRSYDLGVMIGQFRDRIASMIGS 596
Query: 607 DEDAELKLMEKYGIDEITAKAIISYFREQANYSVIPDDETVLVEIVKEGN-VVKYFFHTL 665
ED L+ +Y +DE A++IISY + Q Y IP + L+E +E + V FH
Sbjct: 597 GEDPTEMLINEYHVDENGARSIISYIKAQIEYG-IPTENRALIEGYQESDGVYGLIFHVP 655
Query: 666 IGRRANDALSRAFAYLISKRKRCNVGMAITDNGFMLKVPRDKELSQEEVLELFQVENLRE 725
+GR+ NDALSRA+A IS + N + ITD+GF++ ++++ EE ++ N R+
Sbjct: 656 LGRKVNDALSRAYALAISNKYGSNTRITITDDGFIIYT--ERKIPIEEAVKTVNSSNFRD 713
Query: 726 TLKRALDNTELLKRRFRHVANRGLLVLRRYMGRKKSLSRQQMNAQTLLNFLKRNYPEFPL 785
++R++ NTEL K+RFRH A R L+VLR Y G S++RQQ+ + LLN L++ + +F +
Sbjct: 714 LVRRSIANTELFKQRFRHCAARSLMVLRSYKGYDISVARQQLRSDRLLNELQK-HEDFSI 772
Query: 786 LKEVYREILEDKMDIENAELFLKWIKEGKVKIVVEEHSYPSPFAFNLEVVGASDVVLMED 845
++E YREI+ED MD+ AE ++K + + ++ SPF++ + + G+SD+V+MED
Sbjct: 773 IRETYREIMEDLMDVPRAEQYVKSVMDSHSYMIRNYTRETSPFSYGMIMAGSSDIVMMED 832
Query: 846 RRELIRQLHQKIM 858
R +++R L +++
Sbjct: 833 RSKMLRDLQSRML 845
>pir||F83237 probable ATP-dependent DNA helicase PA3272 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9949397|gb|AAG06660.1|AE004749_9 (AE004749) probable
ATP-dependent DNA helicase [Pseudomonas aeruginosa]
Length = 1448
Score = 457 bits (1164), Expect = e-127
Identities = 302/853 (35%), Positives = 446/853 (51%), Gaps = 36/853 (4%)
Query: 23 PIVREWFKRKFKSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAIISELI--SLGR 80
P+VR+WF+R F + TP Q A I +G + L+++PTGSGKTL+AFLA I L+ L
Sbjct: 23 PVVRQWFERHFAAPTPAQVEAWPAIREGLSTLVAAPTGSGKTLTAFLAAIDALVVEGLAA 82
Query: 81 RGKLEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRTSDTSSY 140
G+L D VYVSPL+AL+NDIR NLE+PL IRE L +IR AVRT DT
Sbjct: 83 GGELADATQVVYVSPLKALSNDIRINLEQPLAGIREELARLGLPDVDIRSAVRTGDTPQV 142
Query: 141 EKSKMLKMPPHILITTPESLAIALNAPRFREKLRDVKWVIVDEVHALAENKRGSHLALTL 200
E+ M K PPHIL+TTPESL I L + R+ L V+ VIVDE+HALA +KRGSHLAL+L
Sbjct: 143 ERGAMRKRPPHILVTTPESLYILLGSESGRQMLAGVRSVIVDEIHALAGSKRGSHLALSL 202
Query: 201 ERLRELTKRDFVRIGLSATIHPLEEVAKFVFGFSDDGKPRPGLIVDVSFAKKTKITVESV 260
ERL+ L R +RIGLSAT P+E+VA+F+ G S + + IVDV + + + +E
Sbjct: 203 ERLQALCPRPLLRIGLSATQKPIEKVARFLVGASGNPRDPACRIVDVGYTRPRDLGIEVP 262
Query: 261 VEDLVYTPANVLNEALYRRIGELVRSRKTTLIFTNTRSGAERVAYHLKKMFPEWEDKIEA 320
L +N E +Y R+ L +TTL+F NTR AERV L + ++ A
Sbjct: 263 PVALEAVMSNDTWELVYDRLAHLAGEHRTTLVFVNTRRMAERVTRFLAERL--GSRQVAA 320
Query: 321 HHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILIGSPKSVNRALQRIG 380
HH SL++E+RL+ E+RLK G+LK++V++ SLELGIDIG ++LV + SP+S+ LQR+G
Sbjct: 321 HHGSLAKELRLDAEQRLKAGQLKVLVATASLELGIDIGDVELVCQLSSPRSIAAFLQRVG 380
Query: 381 RAGHRLHEVSEGVILALDRDDLVEVTVLAHNARKRKLDRIKIPKNPLDVLVQHLLGMALE 440
R+GH + +G + RDDLVE L + R+ +LD + +P+ PLDVL Q ++
Sbjct: 381 RSGHSVGGTPKGRLFPTSRDDLVECAALLDSVRRGELDSLVLPRQPLDVLAQQIVAEVAC 440
Query: 441 RVWEVEEAYKVVRRAYPYHDLPFEDFINVLKYLA-GEFSGLEERKVYAKIWLENGKF-GK 498
+ W ++ Y++V RA PY L E F VL+ LA G S L R Y NG G+
Sbjct: 441 QEWREDDLYRLVIRAEPYAGLERERFDEVLRMLAEGYHSRLGVRGAYLHRDALNGLLRGR 500
Query: 499 RGKMTRAIYYMNTGTIPDEAKIDVFTMDK-KYIGTVEEEFAERLIPGDIFVLAGRTYEFV 557
RG A+ + GTIPD V + +GTV E+FA + GD+F L +Y +
Sbjct: 501 RGARLTAL--TSGGTIPDTGDYSVLLEPQGLLVGTVNEDFAVESLAGDVFQLGNTSYRII 558
Query: 558 KSRGNKIYVIPREGVKPTIPSWFSEMLPLSFDLALDIQKFRREVKSLLND---------- 607
+ ++ V +G P IP W E S +L+ + + R + LL +
Sbjct: 559 RIEPGRVRVEDAQGQPPNIPFWLGEAPGRSDELSASVARLRDTLDELLGEGQALPEGRRL 618
Query: 608 EDAELKLMEKYGIDEITAKAIISYF-REQANYSVIPDDETVLVE-IVKEGNVVKYFFHTL 665
E A L G+D+ A+ I+ Y R + +P +++E E ++ H+
Sbjct: 619 EPAIAWLGATLGLDDGAARQIVEYLARARQALGGLPGSRRLVLERFFDESGGMQLIIHSP 678
Query: 666 IGRRANDALSRAFAYLISKRKRCNVGMAITDNGFMLKVPRDKELSQEEVLELFQVENLRE 725
G R N A A + + A T++ +L + +EV +
Sbjct: 679 HGSRLNRAWGLALRKRFCRSFNFELQAAATEDAIILSLSTSHSFPLDEVWRYLHSASAEH 738
Query: 726 TLKRALDNTELLKRRFRHVANRGLLVLRRYMGRKKSLSRQQMNAQTLLNFL--------- 776
L +A+ + L R+R L + R GRK +M ++ LL +
Sbjct: 739 LLVQAVLDAPLFGVRWRWNLTTSLGLPRYAGGRKVPPQLLRMKSEDLLASVFPDQVACLE 798
Query: 777 ----KRNYPEFPLLKEVYREILEDKMDIENAELFLKWIKEGKVKIVVEEHSYPSPFAFNL 832
+R P+ PL+ + + L + MD E L+ ++ G V ++ + P+P A
Sbjct: 799 NIVGEREVPDHPLVAQTLDDCLHEAMDCEGWLALLRDMESGAVDLLARD--LPAPSALAA 856
Query: 833 EVVGASDVVLMED 845
E++ A ++D
Sbjct: 857 EILTARPYAYLDD 869
>pir||T35694 ATP dependent DNA helicase - Streptomyces coelicolor
>gi|3294249|emb|CAA19862.1| (AL031031) ATP dependent DNA
helicase [Streptomyces coelicolor A3(2)]
Length = 1690
Score = 416 bits (1057), Expect = e-115
Identities = 312/924 (33%), Positives = 461/924 (49%), Gaps = 97/924 (10%)
Query: 23 PIVREWFKRKFKSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAIISELISLGRRG 82
P R WF F + T Q A I +G +VL+ +PTGSGKTL+AFLA + +L S
Sbjct: 14 PATRGWFTGAFSAPTSAQAGAWQAISQGSDVLVVAPTGSGKTLAAFLAALDQLTSTPPPA 73
Query: 83 KLEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRTSDTSSYEK 142
+ + +YVSPL+AL D+ RNL PL IR+ S L PE++V +R+ DT + E+
Sbjct: 74 DPKKRCRVLYVSPLKALAVDVERNLRSPLTGIRQESVRLGLPEPEVKVGIRSGDTPAAER 133
Query: 143 SKMLKMPPHILITTPESLAIALNAPRFREKLRDVKWVIVDEVHALAENKRGSHLALTLER 202
+ PP ILITTPESL + L + R+ L ++ VI+DEVHA+A KRG+HLALTLER
Sbjct: 134 RALSTRPPDILITTPESLFLMLTSAT-RDALTGIETVILDEVHAVAGTKRGAHLALTLER 192
Query: 203 LRELTKRDFVRIGLSATIHPLEEVAKFVFGFSDDGKPRPGL-IVDVSFAKKTKITVESVV 261
L EL + RIGLSAT+ P++EVA+F+ PR + IV K+ ++V V
Sbjct: 193 LDELLPKPARRIGLSATVRPVDEVARFL-------APRGRVEIVQPESGKEFDLSVVVPV 245
Query: 262 EDLVY---TPANVLNEALYR---------RIGELVRSRKTTLIFTNTRSGAERVAYHLKK 309
EDL +P NE R RI +LV+S ++T++F N+R AER+ L +
Sbjct: 246 EDLGELGGSPVAEGNEGAERPSIWPHVEERITDLVQSHRSTIVFANSRRLAERLCNRLNE 305
Query: 310 M---------FPEWEDKIE-----------------AHHSSLSREVRLEVEERLKRGELK 343
+ E E AHH S+S+E R VEE LK G L
Sbjct: 306 IAYERATGEPLDEHHSPAELMGGSGAAQGAPPVIARAHHGSVSKEQRALVEEDLKAGRLP 365
Query: 344 IIVSSTSLELGIDIGTIDLVILIGSPKSVNRALQRIGRAGHRLHEVSEGVILALDRDDLV 403
+V+++SLELGID+G +DLV+ + SP SV LQR+GRAGH++ VS GV+ R DLV
Sbjct: 366 AVVATSSLELGIDMGAVDLVVQVESPPSVASGLQRVGRAGHQVGAVSTGVVFPKYRGDLV 425
Query: 404 EVTVLAHNARKRKLDRIKIPKNPLDVLVQHLLGMALERVWEVEEAYKVVRRAYPYHDLPF 463
+ V+ R ++ ++IP NPLDVL Q L+ M W+V++ VRRA P+ LP
Sbjct: 426 QSAVVTERMRSGAIEALRIPANPLDVLAQQLVAMTALDTWQVDDLLTTVRRAAPFASLPE 485
Query: 464 EDFINVLKYLAGE-----FSGLEERKVYAKIWLENGKFGKRGKMTRAIYYMNTGTIPDEA 518
F VL LAG F+ L R V+ ++ G+ G A+ + GTIPD
Sbjct: 486 SAFTAVLDMLAGRYPSDAFAELRPRVVWDRV--AGTVTGRPGAQRLAV--TSGGTIPDRG 541
Query: 519 KIDVFT--MDKK----YIGTVEEEFAERLIPGDIFVLAGRTYEFVKSRGNKIYVIPREGV 572
VF D K +G ++EE GD+F L ++ +++ V P GV
Sbjct: 542 LFGVFLAGADPKKGGGRVGELDEEMVYESRVGDVFTLGTSSWRIEDITRDRVLVSPAPGV 601
Query: 573 KPTIPSWFSEMLPLSFDLALDIQKFRREVKSLLNDEDAELKLMEKYGIDEITAKAIISYF 632
+P W + L +L + F REV S L+ EDA L+L+ G+D A ++SY
Sbjct: 602 PGRLPFWKGDQLGRPLELGRALGAFLREVGS-LSKEDARLRLVTA-GLDAWAADNVLSYL 659
Query: 633 REQAN-YSVIPDDETVLVEIVK-EGNVVKYFFHTLIGRRANDALSRAFAYLISKRKRCNV 690
EQ +PDD T++VE + E + H+ G + + + A +S+R +
Sbjct: 660 DEQREACGHVPDDRTIVVERFRDELGDWRVVVHSPFGAQVHAPWALALGARLSERYGMDA 719
Query: 691 GMAITDNGFMLKVPRDKELSQEEVLE----------------------LFQVENLRETLK 728
+ D+G +L++P D +L + L+ +F + +
Sbjct: 720 QVMHADDGIVLRLP-DADLMGLDFLDQDPAKPGLEYDAEKAPVGAADVVFDKGEVDRVVT 778
Query: 729 RALDNTELLKRRFRHVANRGLLVLRRYMGRKKSLSRQQMNAQTLLNFLKRNYPEFPLLKE 788
+ + L RFR A R LL+ RR G++ L +Q+ A LL + Y FP++ E
Sbjct: 779 DQVGGSALFASRFRECAARALLLPRRSPGKRTPLWQQRQRAAQLLE-VASEYGSFPIVLE 837
Query: 789 VYREILEDKMDIENAELFLKWIKEGKVKIVVEEHSYPSPFAFNL------EVVGASDVVL 842
RE L+D D+ + ++ KV++V PSPFA +L + + D L
Sbjct: 838 AVRECLQDVFDVPGLVELMGDVETRKVRLVEVTTPEPSPFARSLLFGYVAQFLYEGDSPL 897
Query: 843 MEDRRELIRQLHQKIMAIIASQGQ 866
E RR L +++A + Q +
Sbjct: 898 AE-RRAAALSLDSRLLAELLGQAE 920
>pir||A70982 probable ATP-dependent helicase lhr - Mycobacterium tuberculosis
(strain H37RV) >gi|1877351|emb|CAB07060.1| (Z92771) lhr
[Mycobacterium tuberculosis]
Length = 1513
Score = 404 bits (1026), Expect = e-111
Identities = 278/866 (32%), Positives = 436/866 (50%), Gaps = 59/866 (6%)
Query: 12 YSDEEIYSILDPIVREWFKRKFKSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAI 71
++ S + R+WF F + T Q A I G+N L+ +PTGSGKTL+AFL
Sbjct: 3 FAQPSALSRFSALTRDWFTSTFAAPTAAQASAWAAIADGDNTLVIAPTGSGKTLAAFLWA 62
Query: 72 ISELISLGRRGKLEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVA 131
+ L + +YVSPL+AL D+ RNL PL + L++ P+IRV
Sbjct: 63 LDSLAGSEPMSERPAATRVLYVSPLKALAVDVERNLRTPLAGLTRLAERQGLPAPQIRVG 122
Query: 132 VRTSDTSSYEKSKMLKMPPHILITTPESLAIALNAPRFREKLRDVKWVIVDEVHALAENK 191
VR+ DT + +++ PP +LITTPESL + L + R+ L V+ VI+DE+HA+A K
Sbjct: 123 VRSGDTPPALRRQLVSQPPDVLITTPESLFLMLTSAA-RQTLTGVQTVIIDEIHAIAATK 181
Query: 192 RGSHLALTLERLRELT-KRDFVRIGLSATIHPLEEVAKFVFGFSDDGKPRPGLIVDVSFA 250
RG+HLAL+LERL +L+ +R RIGLSAT+ P EE+A+F+ G S P IV A
Sbjct: 182 RGAHLALSLERLDDLSSRRRAQRIGLSATVRPPEELARFLSGQS------PTTIVAPPAA 235
Query: 251 KKTKITVESVVEDLVYTPANVLNEALYRRIGELVRSRKTTLIFTNTRSGAERVAYHLKKM 310
K +++V+ V D+ N + + R+ +L+ S +T++F N+R AER+ L ++
Sbjct: 236 KTVELSVQVPVPDMANLTDNTIWPDVEARLVDLIESHNSTIVFANSRRLAERLTARLNEI 295
Query: 311 F---------PEWEDKI----------------------EAHHSSLSREVRLEVEERLKR 339
P+ ++ AHH S+S+E R VEE LKR
Sbjct: 296 HAARCGIELAPDTNQQVAGGAPAHIMGSGQTFGAPPVLARAHHGSISKEQRAVVEEDLKR 355
Query: 340 GELKIIVSSTSLELGIDIGTIDLVILIGSPKSVNRALQRIGRAGHRLHEVSEGVILALDR 399
G+LK +V+++SLELGID+G +DLVI + +P SV LQRIGRAGH++ E+S GV+ R
Sbjct: 356 GQLKAVVATSSLELGIDMGAVDLVIQVQAPPSVASGLQRIGRAGHQVGEISRGVLFPKHR 415
Query: 400 DDLVEVTVLAHNARKRKLDRIKIPKNPLDVLVQHLLGMALERVWEVEEAYKVVRRAYPYH 459
DL+ V +++ +++P NPLD+L QH + A + + + VRRA P+
Sbjct: 416 TDLLGCAVSVQRMLAGEIETMRVPANPLDILAQHTVAAAALEPLDADAWFDTVRRAAPFA 475
Query: 460 DLP---FEDFINVL--KYLAGEFSGLEERKVYAKIWLENGKFGKRGKMTRAIYYMNTGTI 514
LP FE +++L KY + EF+ L R VY + + G R R + + G I
Sbjct: 476 TLPRSLFEATLDLLSGKYPSTEFAELRPRLVYDR---DTGTLTARPGAQR-LAVTSGGAI 531
Query: 515 PDEAKIDVF--TMDKKYIGTVEEEFAERLIPGDIFVLAGRTYEFVKSRGNKIYVIPREGV 572
PD V+ T +G ++EE PGD+ L ++ + +++ VIP G
Sbjct: 532 PDRGLFAVYLATERPSRVGELDEEMVYESRPGDVISLGATSWRITEITHDRVLVIPAPGQ 591
Query: 573 KPTIPSWFSEMLPLSFDLALDIQKFRREVKSLLNDEDAELKLMEKYGIDEITAKAIISYF 632
+P W + +L + E+ +L D A G D+ +
Sbjct: 592 PARLPFWRGDDAGRPAELGAALGALTGELAAL--DRTAFGTRCAGLGFDDYATDNLWRLL 649
Query: 633 REQAN-YSVIPDDETVLVEIVK-EGNVVKYFFHTLIGRRANDALSRAFAYLISKRKRCNV 690
+Q +V+P D T+LVE + E + H+ G R + L+ A + R +
Sbjct: 650 DDQRTATAVVPTDSTLLVERFRDELGDWRVILHSPYGLRVHGPLALAVGRRLRDRYGIDE 709
Query: 691 GMAITDNGFMLKVPRDKELSQEE----VLELFQVENLRETLKRALDNTELLKRRFRHVAN 746
+DNG ++++P ++ L +F + + + + + L RFR A
Sbjct: 710 KPTASDNGIVVRLPDTVSAGEDSPPGAELFVFDADEIDPIVTTEVAGSALFASRFRESAA 769
Query: 747 RGLLVLRRYMGRKKSLSRQQMNAQTLLNFLKRNYPEFPLLKEVYREILEDKMDIENAELF 806
R LL+ RR+ GR+ L +Q+ A LL + R YP+FP++ E RE L+D D+
Sbjct: 770 RALLLPRRHPGRRSPLWQQRQRAARLLE-VARKYPDFPIVLETVRECLQDVYDVPILVEL 828
Query: 807 LKWIKEGKVKIVVEEHSYPSPFAFNL 832
+ I + +V++ E + PSPFA +L
Sbjct: 829 MARIAQRRVRVAEAETAKPSPFAASL 854
>sp|P30015|LHR_ECOLI PROBABLE ATP-DEPENDENT HELICASE LHR (LARGE HELICASE-RELATED
PROTEIN) >gi|7466703|pir||G64922 probable ATP-dependent
helicase lhr (EC 3.6.1.-) - Escherichia coli
>gi|993028|gb|AAC37009.1| (L01622) RNA helicase-like
protein [Escherichia coli] >gi|1742726|dbj|BAA15419.1|
(D90809) Probable ATP-dependent helicase Lhr (EC
3.6.1.-) (Large helicase- related protein). [Escherichia
coli] >gi|1787942|gb|AAC74725.1| (AE000260) member of
ATP-dependent helicase superfamily II [Escherichia coli
K12]
Length = 1538
Score = 376 bits (956), Expect = e-103
Identities = 282/912 (30%), Positives = 447/912 (48%), Gaps = 85/912 (9%)
Query: 20 ILDPIVREWFKRKFKSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAIISELISLG 79
+ P R+WF R FK T Q + E+ L+ +PTGSGKTL+AFL + L G
Sbjct: 14 VFSPATRDWFLRAFKQPTAVQPQTWHVAARSEHALVIAPTGSGKTLAAFLYALDRLFREG 73
Query: 80 ----RRGKLEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRTS 135
R +Y+SP++AL D++RNL+ PL+ I + + E +RV +RT
Sbjct: 74 GEDTREAHKRKTSRILYISPIKALGTDVQRNLQIPLKGIADERRRRGETEVNLRVGIRTG 133
Query: 136 DTSSYEKSKMLKMPPHILITTPESLAIALNAPRFREKLRDVKWVIVDEVHALAENKRGSH 195
DT + E+SK+ + PP ILITTPESL + L + R RE LR V+ VI+DEVHA+A +KRG+H
Sbjct: 134 DTPAQERSKLTRNPPDILITTPESLYLMLTS-RARETLRGVETVIIDEVHAVAGSKRGAH 192
Query: 196 LALTLERLRELTKRDFVRIGLSATIHPLEEVAKFVFGFSDDGKPRPGLIVDVSFAKKTKI 255
LAL+LERL L RIGLSAT+ +VA F+ G RP +V+ + +I
Sbjct: 193 LALSLERLDALLHTSAQRIGLSATVRSASDVAAFL------GGDRPVTVVNPPAMRHPQI 246
Query: 256 TVESVV---EDLVYTPANVLNEALYRRIGEL-----------VRSRKTTLIFTNTRSGAE 301
+ V +D+ + ++ R G + V ++T++FTN+R AE
Sbjct: 247 RIVVPVANMDDVSSVASGTGEDSHAGREGSIWPYIETGILDEVLRHRSTIVFTNSRGLAE 306
Query: 302 RVAYHLKKMFPEWEDK-----------------------------IEAHHSSLSREVRLE 332
++ L +++ + +HH S+S+E R
Sbjct: 307 KLTARLNELYAARLQRSPSIAVDAAHFESTSGATSNRVQSSDVFIARSHHGSVSKEQRAI 366
Query: 333 VEERLKRGELKIIVSSTSLELGIDIGTIDLVILIGSPKSVNRALQRIGRAGHRLHEVSEG 392
E+ LK GEL+ +V+++SLELGID+G +DLVI + +P SV LQRIGRAGH++ VS+G
Sbjct: 367 TEQALKSGELRCVVATSSLELGIDMGAVDLVIQVATPLSVASGLQRIGRAGHQVGGVSKG 426
Query: 393 VILALDRDDLVEVTVLAHNARKRKLDRIKIPKNPLDVLVQHLLGMALERVWEVEEAYKVV 452
+ R DLV+ V+ +L+ + P NPLDVL Q + A +V+E Y V
Sbjct: 427 LFFPRTRRDLVDSAVIVECMFAGRLENLTPPHNPLDVLAQQTVAAAAMDALQVDEWYSRV 486
Query: 453 RRAYPYHDLP---FEDFINVL--KYLAGEFSGLEERKVYAKIWLENGKFGKR-GKMTRAI 506
RRA P+ DLP F+ +++L +Y +G+FS + V+ + E G R G A+
Sbjct: 487 RRAAPWKDLPRRVFDATLDMLSGRYPSGDFSAFRPKLVWNR---ETGILTARPGAQLLAV 543
Query: 507 YYMNTGTIPDEAKIDVFTMD------KKYIGTVEEEFAERLIPGDIFVLAGRTYEFVKSR 560
+ GTIPD V + + +G ++EE DI L ++ +
Sbjct: 544 --TSGGTIPDRGMYSVLLPEGEEKAGSRRVGELDEEMVYESRVNDIITLGATSWRIQQIT 601
Query: 561 GNKIYVIPREGVKPTIPSWFSEMLPLSFDLALDIQKFRREVKSLLNDEDAELKLMEKYGI 620
+++ V P G +P W E +L I F LL D + +
Sbjct: 602 RDQVIVTPAPGRSARLPFWRGEGNGRPAELGEMIGDFLH----LLADGAFFSGTIPPWLA 657
Query: 621 DEITAKAIISYFREQANYS-VIPDDETVLVEIVK-EGNVVKYFFHTLIGRRANDALSRAF 678
+E T I EQ N + ++P +++E + E + H+ GRR ++ + A
Sbjct: 658 EENTIANIQGLIEEQRNATGIVPGSRHLVLERCRDEIGDWRIILHSPYGRRVHEPWAVAI 717
Query: 679 AYLISKRKRCNVGMAITDNGFMLKVPRDKELSQEEVLELFQVENLRETLKRALDNTELLK 738
A I + + +D+G + ++P + + LF+ E L + ++ A+ ++ L
Sbjct: 718 AGRIHALWGADASVVASDDGIVARIPDTDGKLPDAAIFLFEPEKLLQIVREAVGSSALFA 777
Query: 739 RRFRHVANRGLLVLRRYMGRKKSLSRQQMNAQTLLNFLKRNYPEFPLLKEVYREILEDKM 798
RFR A R LL+ R G + L +Q++ A LL + + YP+FP++ E RE L+D
Sbjct: 778 ARFRECAARALLMPGRTPGHRTPLWQQRLRASQLLE-IAQGYPDFPVILETLRECLQDVY 836
Query: 799 DIENAELFLKWIKEGKVKIVVEEHSYPSPFAFNL------EVVGASDVVLMEDRRELIRQ 852
D+ E ++ + G+++I + PSPFA +L E + SD L E RR +
Sbjct: 837 DLPALERLMRRLNGGEIQISDVTTTTPSPFATSLLFGYVAEFMYQSDAPLAE-RRASVLS 895
Query: 853 LHQKIMAIIASQ 864
L +++ + Q
Sbjct: 896 LDSELLRNLLGQ 907
>pir||C71004 probable ATP-dependent helicase - Pyrococcus horikoshii
>gi|3257752|dbj|BAA30435.1| (AP000006) 912aa long
hypothetical ATP-dependent helicase [Pyrococcus
horikoshii]
Length = 912
Score = 373 bits (948), Expect = e-102
Identities = 263/855 (30%), Positives = 449/855 (51%), Gaps = 100/855 (11%)
Query: 24 IVREWFKRKFKSFTPPQRYAIVEIH-KGENVLISSPTGSGKTLSAFLAIISELISLGRRG 82
++++ K KF Q A I+ +GE+VLI +PTGSGKT +A + +I+ ++ R
Sbjct: 4 VLKKAIKEKFGKLNKLQIQAFKAIYGEGESVLIIAPTGSGKTEAAIIPVINSILKDNLR- 62
Query: 83 KLEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRTSDTSSYEK 142
I C+Y++PL+ALN D+ L+ ++ ++ I+V VR DT +
Sbjct: 63 ----PISCLYIAPLKALNRDL-------LERLKWWGEKTG-----IKVEVRHGDTPQSMR 106
Query: 143 SKMLKMPPHILITTPESLAIALNAPRFREKLRDVKWVIVDEVHALAENKRGSHLALTLER 202
+K +K PPHILITTPESL L R+ L +VK+VIVDE+ L +NKRG L L L+R
Sbjct: 107 AKQVKNPPHILITTPESLPAILTTKSLRKYLENVKFVIVDEITELVDNKRGIQLILNLKR 166
Query: 203 LRELTKRDFVRIGLSATIHPLEEVAKFVFGFSDDGKPRPGLIVDVSFAKKTKITV----- 257
L + DF+RIGLSAT+ EE+ ++ I+ K+ K V
Sbjct: 167 LSLIA--DFIRIGLSATVGNEEEIREWF---------EAKRIIKPHLKKRYKFKVLYPQP 215
Query: 258 ---ESVVEDLVYTPANVLNEALYRRIGELVRSRKTTLIFTNTRSGAERVAYHLKKMFPEW 314
+ + + + P +V R + E+V K LIF NTR AE + + LK W
Sbjct: 216 KPEDQELAEKLKVPGDVATRL--RTLWEIVEKYKKALIFVNTRQFAEILGHRLKT----W 269
Query: 315 EDKIEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILIGSPKSVNR 374
+E HH SLS+E R+E E +LK G++K ++ ++S+ELGIDIG +D+VI SP+ VNR
Sbjct: 270 GKPVEVHHGSLSKEARIEAERKLKEGKIKALICTSSMELGIDIGDVDVVIQYMSPRQVNR 329
Query: 375 ALQRIGRAGHRLHEVSEGVILALDRDDLVEVTVLAHNARKRKLDRIKIPKNPLDVLVQHL 434
+QR GR+ HRL EVSE I+ +D ++ V+A A + KL+ +K +N LDVL +
Sbjct: 330 LIQRAGRSRHRLWEVSEAYIITTGVEDYLQGLVIAKRALEGKLEGVKPYENALDVLAHFI 389
Query: 435 LGMALE-RVWEVEEAYKVVRRAYPYHDLPFEDFINVLKYL--AGEFSGLEERKVYAKIWL 491
+G+ +E R ++ E Y++ + YPY L +ED++ VL+ L AG E+R
Sbjct: 390 VGLLIEYRDLKINEPYRLAKDTYPYRKLRWEDYLRVLEILEEAGIIKRHEDRL------- 442
Query: 492 ENGKFGKRGKMTRAIYYMNTGTIPDEAKIDVF-TMDKKYIGTVEEEFAERLIPGDIFVLA 550
+ G+ + Y+ N TIPDE V + K IG ++E F L G F++
Sbjct: 443 ------RLGRKSFKYYFENLSTIPDEVSYKVIDVVSGKLIGRLDENFVINLEEGIEFIMH 496
Query: 551 GRTYEFVKSRGNKIYVIPREGVKPTIPSWFSEMLPLSFDLALDIQKFRREVKSLLNDEDA 610
G+++ ++ + + I V E ++ IPSW E++P+ +++A+++ + RRE L+ D++
Sbjct: 497 GKSWLVLEIKDDVIKVRESENIEGAIPSWEGELIPVPYEVAIEVGRLRRE---LVQDKER 553
Query: 611 ELKLMEKYGIDEITAKAIISYFREQANYSVIPDDETVLVEIVKEGNVVKYFFHTLIGRRA 670
++L++ G++ + I+ R + N +IP D +L+ + +V H+ G +
Sbjct: 554 AIRLIK--GVEFEEKELDIARERLKEN-DLIPSDRDILISVFPNLVIV----HSDFGNKT 606
Query: 671 NDALSRAFAYLISKRKRCNVGMAITDNGFMLKVPRDKELSQEEVLELFQVE-NLRETLKR 729
N+ L+R +S + NG ++ P +++ +E+ ++ +++ N+RE + R
Sbjct: 607 NEGLARYILAFLSLKYGKIFSARTQSNGIIITTP--FKMNPDEIKDILRIKGNVREIISR 664
Query: 730 ALDNTELLKRRFRHVANRGLLVLRRYMGRKKSLSRQQMNAQTLLNFLKRNYPEFPLLKEV 789
AL ++ + + + +VA R MG + +R + ++R + + + E
Sbjct: 665 ALKDSPIYRWKMLNVAKR--------MGALRKDAR--------IKKVERLFEDTIIEVET 708
Query: 790 YREILEDKMDIENAELFLKWIKEGKVKI---VVEEHSYPSPFAFNLEVVGASDVVLME-- 844
+ EI DK+D+E LK IK+G++++ ++EE P + LE + LM
Sbjct: 709 FNEIFHDKVDVERVNTVLKKIKDGEIRVKGRILEE-----PTSLELEYMRLRGEFLMTSP 763
Query: 845 -DRRELIRQLHQKIM 858
D +E+ +K++
Sbjct: 764 LDEKEIELLFKEKLL 778
>gi|11498749 large helicase-related protein (lhr-1) [Archaeoglobus fulgidus]
>gi|7446074|pir||D69393 large helicase-related protein
(lhr-1) homolog - Archaeoglobus fulgidus
>gi|2649437|gb|AAB90094.1| (AE001024) large
helicase-related protein (lhr-1) [Archaeoglobus
fulgidus]
Length = 892
Score = 358 bits (908), Expect = 2e-97
Identities = 254/832 (30%), Positives = 435/832 (51%), Gaps = 77/832 (9%)
Query: 34 KSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAIISELISLGRRGKLEDKIYCVYV 93
+ T Q A +I G++VLI +PTGSGKT +A + I ++ + + + I +Y+
Sbjct: 16 EELTELQLEAFRKILSGKDVLIIAPTGSGKTEAAIIPIFEAMLKMEK----PEGIVAIYI 71
Query: 94 SPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRTSDTSSYEKSKMLKMPPHIL 153
+PLRALN D+ L+ IR +++ L IRV VR DT ++++ + PPH+L
Sbjct: 72 TPLRALNRDM-------LRRIRGIAEFLG-----IRVDVRHGDTPDSQRARQSRKPPHLL 119
Query: 154 ITTPESLAIALNAPRFREKLRDVKWVIVDEVHALAENKRGSHLALTLERLRELTKRDFVR 213
ITTPE+ I R+ L++V++V+VDE+H L +++RG L++ LERLRE+ + F
Sbjct: 120 ITTPETFQILFLGKNLRKALKNVRYVVVDEIHELIDSERGVQLSVALERLREMAR--FQT 177
Query: 214 IGLSATIHPLEEVAKFVFGFSD--DGKPRPGLIVDVSFAKKTKITVESVVEDLVYTPANV 271
IGLSAT+ + V++FV ++ + K ++V K V+ + + A +
Sbjct: 178 IGLSATVSRPKLVSRFVGADAEVLEWKAEKEYEIEV-----VKPEVDEKLAAKLGVDAEI 232
Query: 272 LNEALYRRIGELVRSRKTTLIFTNTRSGAERVAYHLKKMFPEWEDKIEAHHSSLSREVRL 331
E + I + V+ + LIF NTR AE + LKK+ +E HH SLSRE R+
Sbjct: 233 AGELKF--IADAVKEHGSALIFVNTRQTAEALGIKLKKLID-----VEVHHGSLSRETRV 285
Query: 332 EVEERLKRGELKIIVSSTSLELGIDIGTIDLVILIGSPKSVNRALQRIGRAGHRLHEVSE 391
E EER +GEL ++ ++S+ELGIDIG ++LV+ SP+ R +QR+GR+GH L VS+
Sbjct: 286 EAEERFAKGELDALICTSSMELGIDIGHVNLVVQYNSPRQAVRLVQRVGRSGHGLGRVSK 345
Query: 392 GVILALDRDDLVEVTVLAHNARKRKLDRIKIPKNPLDVLVQHLLGMALE--RVWEVEEAY 449
G ++A DD++E V+ A++ L+ +I DVL + +ALE R+ + E+A+
Sbjct: 346 GYVVASSFDDILESAVIVRRAKEGLLEDAEIHFKSFDVLANQICALALEYGRI-DAEKAH 404
Query: 450 KVVRRAYPYHDLPFEDFINVLKYLAGEFSGLEERKVYAKIWLENGKFGKRGKMTRAIYYM 509
++V+RA+PY +L FE+F V +LA KI+ + G+ G R + TR +Y
Sbjct: 405 RIVKRAFPYRNLTFEEFDEVCNFLAR----------IGKIFYDEGEIGAR-RNTRRYFYE 453
Query: 510 NTGTIPDEAKIDVFTMDK-KYIGTVEEEFAERLIPGDIFVLAGRTYEFVKSRGNKIYVIP 568
N IPDE V + K IG+++E F G+IF + G + + +++ +
Sbjct: 454 NISMIPDEKHYRVVDVSSGKTIGSLDESFLS-TFSGEIFAMKGELWRVLSV--DEVVRVE 510
Query: 569 REGVKPTIPSWFSEMLPLSFDLALDIQKFRREVKSLL--NDEDAELKLMEKYGIDEITAK 626
+ IPSW E +P+ F++A ++ R + L+ E A LK + G + K
Sbjct: 511 PVSAEGEIPSWVGEEIPVPFEVAQEVGMLRNWLAGLIKAKGEKAALKALGAKGDVSVVVK 570
Query: 627 AIISYFREQANYS-VIPDDETVLVEIVKEGNVVKYFFHTLIGRRANDALSRAFAYLISKR 685
+ REQ +P D + +E + VV F G + N+ L R A L++ R
Sbjct: 571 TL----REQIEKGFAVPYDSHITIEGSENVVVVNACF----GHKVNETLGRILALLLTAR 622
Query: 686 KRCNVGMAITDNGFMLKVPRDKELSQEEVLELFQVENLRETLKRALDNTELLKRRFRHVA 745
+ +V + I + + +K+ K E +L+ Q E + +RA+ +T L++ + + A
Sbjct: 623 RGSSVAVEI--DPYRIKLSPAKPEEVESILKSIQPEAVESLAERAVFDTRLMQWKVVNAA 680
Query: 746 NRGLLVLRRYMGRKKSLSRQQMNAQTLLNFLKRNYPEFPLLKEVYREILEDKMDIENAEL 805
+ ++ ++ LSR +N ++L+ LK + P+ +E REI +KMD+E
Sbjct: 681 RK-----FGFLSKEDELSR--INVRSLVVKLK----DTPIYREALREIFVEKMDVERTAE 729
Query: 806 FLKWIKEGKVKIVVEEHSYPSPFAFNLEVVGASDVVLMEDRRELIRQLHQKI 857
++ I G++++ V P A A D++ ++ ++R +++
Sbjct: 730 VVEKISSGEIEVSVYNELSPISLAARQR---AMDILAVKSSEAILRAFRERL 778
>pir||B75127 large helicase-related protein (lhr-1) PAB1817 - Pyrococcus abyssi
(strain Orsay) >gi|5458242|emb|CAB49731.1| (AJ248285)
large helicase-related protein (lhr-1) [Pyrococcus
abyssi]
Length = 912
Score = 348 bits (884), Expect = 1e-94
Identities = 252/809 (31%), Positives = 421/809 (51%), Gaps = 90/809 (11%)
Query: 24 IVREWFKRKFKSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAIISELISLGRRGK 83
++++ K KF+ Q A I +G++VLI +PTGSGKT +A L +++ ++ G
Sbjct: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGL--- 60
Query: 84 LEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRTSDTSSYEKS 143
I C+Y++PL+ALN D+ L+ E IR+ VR DT+ Y ++
Sbjct: 61 --PPISCLYIAPLKALNRDLLERLK------------WWEAKTGIRIDVRHGDTTQYRRA 106
Query: 144 KMLKMPPHILITTPESLAIALNAPRFREKLRDVKWVIVDEVHALAENKRGSHLALTLERL 203
K ++ PPH+LITTPE+L L R L++V++V+VDEV L +NKRG+ L L L+RL
Sbjct: 107 KQVRNPPHVLITTPETLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRL 166
Query: 204 RELTKRDFVRIGLSATIHPLEEVAKFVFGFSDDGKPRPGLIVDVSFAKKTKITV------ 257
+ DF+RIGLSAT+ EEV +++ G + KP K+ K V
Sbjct: 167 SLIA--DFIRIGLSATVGNEEEVKEWL-GVDEIVKP--------PLKKRYKFKVLFPRPR 215
Query: 258 --ESVVEDLVYTPANVLNEALYRRIGELVRSRKTTLIFTNTRSGAERVAYHLKKMFPEWE 315
+ + +L+ V A R + E+V K L+F NTR AE +A+ LK W
Sbjct: 216 PEDKELAELLRVDVEVA--ARLRTLWEIVEKHKRVLVFVNTRQFAEVLAHRLKT----WG 269
Query: 316 DKIEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILIGSPKSVNRA 375
+E HH SLS+E R+E E +LK G++K ++ ++S+ELGIDIG +D VI SP+ VNR
Sbjct: 270 KPVEVHHGSLSKEARIEAERKLKEGKVKALICTSSMELGIDIGEVDAVIQYMSPRQVNRL 329
Query: 376 LQRIGRAGHRLHEVSEGVILALDRDDLVEVTVLAHNARKRKLDRIKIPKNPLDVLVQHLL 435
+QR GR+ HRL EVSE I+A +D ++ ++A A + KL+RIK +N LDVL ++
Sbjct: 330 IQRAGRSKHRLLEVSEAYIIATGVEDYLQSLIIAKRAIEGKLERIKPYENALDVLAHFIV 389
Query: 436 GMALE-RVWEVEEAYKVVRRAYPYHDLPFEDFINVLKYLAGEFSGLEERKVYAKIWLENG 494
G+ +E + V E Y++ + YPY +L +E ++ V+ L E +G+ R E G
Sbjct: 390 GLLIEYQKLNVHEPYRMAKETYPYRNLKWEHYLEVINVL--EDAGIIRR--------EEG 439
Query: 495 KFGKRGKMTRAIYYMNTGTIPDEAKIDVFTMDK-KYIGTVEEEFAERLIPGDIFVLAGRT 553
K G+ Y+ N TIPDE V + K IG ++E F L G F++ GR+
Sbjct: 440 IL-KLGRRAFKYYFDNLSTIPDEVSYKVVDIGSGKVIGRLDENFVMDLEEGMEFIMHGRS 498
Query: 554 YEFVKSRGNKIYVIPR--EGVKPTIPSWFSEMLPLSFDLALDIQKFRREVKSLLNDEDAE 611
+ ++ G + + R E ++ IPSW E++P+ +++A ++ + RR +LL D
Sbjct: 499 WLVLEIDGENLIIKVRESENIEGAIPSWEGELIPVPYEVAREVGRLRR---TLLYDPRKA 555
Query: 612 LKLMEKYGIDEITAKAIISYFREQANYSVIPDDETVLVEIVKEGNVVKYFFHTLIGRRAN 671
L++ G+ E + + ++IP D +++ ++ + ++ H+ +G + N
Sbjct: 556 PDLIK--GV-EFNGEELELALNSLKQNTLIPSDRDIIITVLPDTVII----HSDLGNKVN 608
Query: 672 DALSR-AFAYLISKRKRCNVGMAITDNGFMLKVPRDKELSQEEVLE-LFQVENLRETLKR 729
+ +SR +L SK R + + +++ EV E L + + + + +
Sbjct: 609 EGISRYILGFLYSKYGRV---FTAKSQAHSIIIHAPFKMNPNEVKEILLKDYDTKTIISK 665
Query: 730 ALDNTELLKRRFRHVANRGLLVLRRYMGRKKSLSRQQMNAQTLLNFLKRNYPEFPLLK-E 788
+ ++ + + + +VA R MG +R + N Q L E +++ E
Sbjct: 666 TIRDSTVYRWKMINVAKR--------MGALSKRARIR-NVQKLF--------EGTIIEVE 708
Query: 789 VYREILEDKMDIENAELFLKWIKEGKVKI 817
E+ DK+D++ E LK I +G+++I
Sbjct: 709 TLNEVFHDKVDVQKVEEVLKLIAKGEIRI 737
>emb|CAC11967.1| (AL445065) Large helicase related protein [Thermoplasma
acidophilum]
Length = 894
Score = 315 bits (798), Expect = 2e-84
Identities = 243/810 (30%), Positives = 401/810 (49%), Gaps = 99/810 (12%)
Query: 12 YSDEEIYSILDPIVREWFKRKFKSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAI 71
Y DE I ++L R T PQ I + +G+NVL+ SPTGSGKT +A L +
Sbjct: 7 YLDERIIAMLRD-------RGITDPTDPQEQIIPLVLEGKNVLLLSPTGSGKTEAAVLPV 59
Query: 72 ISELISLGRRGKLEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVA 131
++ + K++ +Y++PLRALN DI L + + +EL I V
Sbjct: 60 FQRILR-----EKPKKVFALYITPLRALNRDI-------LSRLVDYGRELG-----IDVQ 102
Query: 132 VRTSDTSSYEKSKMLKMPPHILITTPESLAIALNAPRFREKLRDVKWVIVDEVHALAENK 191
VR SD S +K +M + PP IL+TTPESL I LN R + +V+ VIVDE+H AEN+
Sbjct: 103 VRHSDMSDADKRRMAESPPDILVTTPESLQILLNGKNLRRFIANVRVVIVDELHDAAENE 162
Query: 192 RGSHLALTLERLRELTKRDFVRIGLSATIHPLEEVAKFVFGFSDDGKPRPGLIVDVSFAK 251
RGS L+L LERLR+L +F RIGLSAT+ ++A+F+ +G I+ + K
Sbjct: 163 RGSQLSLALERLRDLAG-NFQRIGLSATVGNPGDLARFLV---PNGTCE---IISTTLKK 215
Query: 252 KTKITV----ESVVEDLVYTPANVLNEALYRRIGELVRSRKTTLIFTNTRSGAERVAYHL 307
I V ES ED + ++ +L+ +L+F N R AE +A+ L
Sbjct: 216 NMSIDVMVPDESSEEDAEVMGCDRQYAGAILKVWDLINRHAGSLVFVNRRFVAEDLAFRL 275
Query: 308 KKMFPEWEDKIEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILIG 367
K F E + HH SLS+E R E K GE+K ++ ++SLELGID+GT + VI
Sbjct: 276 KLKFGEIP--VLVHHGSLSKETREFAERSFKNGEVKALICTSSLELGIDVGTANAVIQFN 333
Query: 368 SPKSVNRALQRIGRAGHRLHEVSEGVILALDRDDLVEVTVLAHNARKRKLDRIKIPKNPL 427
SP+ +N+ +QRIGR+ H + + S+G ++ D ++ E + + + K++ ++I KN L
Sbjct: 334 SPRQINKMIQRIGRSEHWIGKTSKGYVVCTDVIEMEEAIAIVDSIAEGKIENVQIMKNSL 393
Query: 428 DVLVQHLLG-MALERVWEVEEAYKVVRRAYPYHDLPFEDFINVLKYLAGEFSGLEERKVY 486
L +L + + V+ ++ V+R+Y Y DLP++++ +V+ +LA
Sbjct: 394 STLANQILSEINAQGKVNVKNFFETVKRSYAYADLPWDEYYSVVSFLAST---------- 443
Query: 487 AKIWLENGKFGKRGKMTRAIYYMNTGTIPDEAKIDVFTMDKKYIGTVEEEF-AERLIPGD 545
K+WLE+ G+R + T Y N IP E V K+IGT++E + A + G
Sbjct: 444 RKLWLEDELMGRR-RNTLKYYIENISMIPSEKNYKVIDTGGKFIGTLDERYVASEIDAGS 502
Query: 546 IFVLAGRTYEFVKSRGNKIYVIPREGVKPTI-PSWFSEMLPLSFDLALDIQKFRREVKSL 604
FV+ G T+ V+ ++I V P I P W E +P+ +D+ + R+ +S+
Sbjct: 503 YFVMRGNTWRVVRIDHDRILV--ESFFTPAIAPRWTGEDIPVLYDVVQRVSA-NRKSRSI 559
Query: 605 LN--DEDAELKLMEKYGIDEITA-KAIISYFREQANYSVIPDDETVLVEIVKEGNVVKYF 661
LN D+ + KL E Y D T + II F ++ ++++I
Sbjct: 560 LNYIDDASARKLEEWYQNDIATVDRVIIESFNDE-----------IIIQI---------- 598
Query: 662 FHTLIGRRANDALSRAFAYLISKRKRCNVGMAITDNGFMLKVPRDKELSQEEVLELFQ-- 719
L+G R N AL+ + +++ +V M + L+ R ++ E+V+ + +
Sbjct: 599 ---LLGTRGNFALAEILSNVLTSITGESVEMDFSPYHIYLRTSR--KIYAEDVMRMIKSI 653
Query: 720 -VENLRETLKRALDNTELLKRRFRHVANRGLLVLRRYMGRKKSLSRQQMNAQTL-LNFLK 777
+ENL ++ + + K F Y RK + + + + + ++ +
Sbjct: 654 NLENLNSYIRSSASRSRFFKSVF------------LYEARKFGIISEDADLERIRVDKIM 701
Query: 778 RNYPEFPLLKEVYREILEDKMDIENAELFL 807
Y E + ++ R+++ D MDI+ F+
Sbjct: 702 DAYSESVVFEDSIRKLINDYMDIDAITSFI 731
>gb|AAG19610.1| (AE005050) ATP-dependent helicase; HelA [Halobacterium sp. NRC-1]
Length = 946
Score = 303 bits (769), Expect = 4e-81
Identities = 244/806 (30%), Positives = 378/806 (46%), Gaps = 64/806 (7%)
Query: 30 KRKFKSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAIISELISLGRRGKLEDKIY 89
+R F + T PQR A+ + G N L+ +PTG+GKT +A L + L+S G D
Sbjct: 25 ERGFTTPTEPQRRAVPALADGRNGLVVAPTGTGKTETAMLPVFDALVS---DGGPPDGFG 81
Query: 90 CVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRTSDTSSYEKSKMLKMP 149
+YV+PLRALN D+R L+ E + V VR DT+ Y++ + P
Sbjct: 82 ALYVTPLRALNRDMRERLD------------WWGETLGLEVDVRHGDTTDYQRRQQATDP 129
Query: 150 PHILITTPESLAIALNAPRFREKLRDVKWVIVDEVHALAENKRGSHLALTLERLRELTKR 209
P +L+TTPE+L L R+ L DV+ V+VDEVH LA KRG+ LA+ LERL E+ R
Sbjct: 130 PDVLVTTPETLQAMLTGSTLRDGLADVEHVVVDEVHELAGAKRGAQLAIGLERLVEVAGR 189
Query: 210 DFVRIGLSATIHPLEEVAKFVFGFSDDGKPRPGLIVDVSFAKKTKITV---ESVVEDLVY 266
RIGLSAT+ E+ F+ G + +VSF + E + +L+
Sbjct: 190 -VQRIGLSATVGDPHEIGAFLTGGRGCEIIEVDVTSNVSFEVREPAVTDADERLASELLT 248
Query: 267 TPANVLNEALYRRIGELVRSRKTTLIFTNTRSGAERVAYHLKKMFPEWEDKIEAHHSSLS 326
TPA + R I E+V + LIF NTR AE L F E + I HH SLS
Sbjct: 249 TPAMASH---VRAIREIVDRHDSVLIFVNTRQTAEA----LGSRFKELDANIGVHHGSLS 301
Query: 327 REVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILIGSPKSVNRALQRIGRAGHRL 386
++ R++VE+R K G+L ++ ++S+ELGID+G ID V+ SP+ V R LQR+GRAGH
Sbjct: 302 KDARIDVEDRFKSGDLDGLLCTSSMELGIDVGGIDHVVQYNSPREVKRLLQRVGRAGHSR 361
Query: 387 HEVSEGVILALDRDDLVEVTVLAHNARKRKLDRIKIPKNPLDVLVQHLLGMALERVWEVE 446
VSEG ++ DD +E +A A + ++ ++ LD + ++G+ ++ V E E
Sbjct: 362 DAVSEGTVITGSTDDTLEALAVADRANEGAVEDTQVHHGSLDTVANQIVGVVMD-VGETE 420
Query: 447 --EAYKVVRRAYPYHDLPFEDFINVLKYLAGEFSGLEERKVYAKIWLENGKFGKRGKMTR 504
AY ++ RAYP+ L E F V L R VY E+ T
Sbjct: 421 AWHAYNIITRAYPFKQLTEETFRAVAMELH------RNRVVYVD---EDDDTISTSGGTW 471
Query: 505 AIYYMNTGTIPDEAKIDVFTM-DKKYIGTVEEEFAERLI-PGDIFVLAGRTYEF--VKSR 560
YY N IPDE +V+ M + +GT++E F PG FV G + +
Sbjct: 472 QYYYANLSMIPDEETYEVYDMAGGRQVGTLDERFVVNFAEPGATFVQRGEMWRITNIDED 531
Query: 561 GNKIYVIPREGVKPTIPSWFSEMLPLSFDLALDIQKFR----REVKSLLNDEDAELKLME 616
++ V P E +PSW + +P+ + +A + R R++ + + +
Sbjct: 532 DQQVEVSPIEDPAGEVPSWTGQEIPVPYAVAQAVGGMRATGGRQLGTGTPKDAVARDVAA 591
Query: 617 KYGIDEITAKAIISYFREQANY--SVIPDDETVLVEIVKEGNVVKYFFHTLIGRRANDAL 674
+Y TA + + + +P E ++VE VV F G N+ L
Sbjct: 592 RYPTTHRTAGSALDRMARHVTEQDAPVPSAERIVVEQAGSTVVVNACF----GHEVNETL 647
Query: 675 SRAFAYLISKRKRCNVGMAITDNGFMLKVP-RDKELSQEEVLELFQVENLRETLKRALDN 733
R + L+ ++ +VG+ L+VP R VL +++ L+ +L
Sbjct: 648 GRLVSALLGQQTGSSVGLDAGPYRIELEVPSRVSATDVVAVLRDTDPDHVAGLLELSLKQ 707
Query: 734 TELLKRRFRHVANRGLLVLRRYMGRKKSLSRQQMNAQTLLNFLKRNYPEFPLLKEVYREI 793
+E LK VA + L+R+ G R + LL L+ P+ +E RE+
Sbjct: 708 SETLKFTLAQVAAK-FGALKRWKG------RDGVGLSRLLGALEGT----PVYEEAIREV 756
Query: 794 LEDKMDIENAELFLKWIKEGKVKIVV 819
+D+ A L ++ G++ + +
Sbjct: 757 FHTTLDVARASDVLARVQSGELGVEI 782
>gb|AAK40723.1| ATP-dependent helicase [Sulfolobus solfataricus]
Length = 913
Score = 282 bits (715), Expect = 8e-75
Identities = 225/811 (27%), Positives = 399/811 (48%), Gaps = 101/811 (12%)
Query: 30 KRKFKSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAIISELISLGRRGKLEDKIY 89
K ++ TP Q+ AI ++ G+NVLI +PTG GKT +A L I + +KI
Sbjct: 14 KLGYEDLTPIQKIAIPKVLSGKNVLIIAPTGYGKTEAAILPIFYTIFK-----DKPEKIS 68
Query: 90 CVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRTSDTSSYEKSKMLKMP 149
+Y++PLRALN D+ L R L + N I V VR D+S E+ ++L P
Sbjct: 69 TLYITPLRALNRDLELRL-------RRLGEAFN-----ISVNVRHGDSSQKERKEILDNP 116
Query: 150 PHILITTPESLAIALNAPRFREKLRDVKWVIVDEVHALAENKRGSHLALTLERLRELTKR 209
P +L+ TPE+L + FR+ ++KW+I+DE+ + + KRG L++ ++R++++ R
Sbjct: 117 PDVLLVTPETLLYLVLNDTFRKYFTNLKWIIIDELQEMLDEKRGIELSVLIQRIKKIATR 176
Query: 210 DFVR-IGLSATIHPLEEVAKFVFGFSDDGKPRPGLI-------VDVSFAKKTKITVESVV 261
+ ++ IG+SATI +E +++ +G+ I VD+ K K + V
Sbjct: 177 NKIQLIGISATIGDVEIAKRYL---DREGEVEIANINAIKDIKVDLILPKVEKKDADLAV 233
Query: 262 EDLVYTPANVLNEALYRRIGELVRSRKTTLIFTNTRSGAERVAYHLKKMFPEWEDKIEAH 321
+ L P + A ++ E++++ K +IFTNTR +E +A ++ + KI +H
Sbjct: 234 K-LGLRPDTI---ARLEKLNEIIKNNKPIIIFTNTRETSEFIA---NQLMSNYSLKIASH 286
Query: 322 HSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILIGSPKSVNRALQRIGR 381
H SLSRE+R++ E K G + IV+++SLELGIDIG I+LV+ SP+ V R +QR+GR
Sbjct: 287 HGSLSREIRIKTENDFKNGNIDAIVATSSLELGIDIGRINLVVQYMSPRQVIRLIQRVGR 346
Query: 382 AGHRLHEVSEG-VILALDRDDLVEVTVLAHNARKRKLDRIKIPKNPLDVLVQHLLGMALE 440
+GH++ S G VI + D D++E + L++ +NPLDV + GM LE
Sbjct: 347 SGHKIGRTSIGYVIPSEDLFDILECRAIIEALYSGYLEKPLFEENPLDVAAHEIAGMVLE 406
Query: 441 RVWEVEEAYKVVRRAYPYHDLPFEDFINVLKYLAGEFSGLEERKVYAKIWLENGKFGKRG 500
+E +++R ++ + + E F NV++ LE K+ + E+G
Sbjct: 407 GYKNPKEMMEILRNSFYFENFTDEMFENVIEL-------LESAKIVKR--REDGSLFPSR 457
Query: 501 KMTRAIYYMNTGTIPDEAK----IDVFTMDKKYIGTVEEEFAERLIPGDIFVLAGRTYEF 556
++ + YY T IPD + ID T K IGT++E+F L +F+L R ++
Sbjct: 458 RIWK--YYYTTNMIPDSIRSYIVIDHATNMK--IGTLDEDFVVTLDEDSVFILGSRLWKV 513
Query: 557 VKSRGNKIYVIPREGVKPTIPSWFSEMLPLSFDLALDIQKFRREVKSLLNDEDAELKLME 616
V ++I+V E +PSWF E +P+ ++A + ++ V+ E
Sbjct: 514 VSIENDRIFVERAELKNGILPSWFGESIPVEKEIARKVYEYIYAVEK------------E 561
Query: 617 KYGIDEITAKAIISYFREQANYSVIPDDETVLVEIVKEGNVVKYFFHTLIGRRANDALSR 676
K ++ + ++ + ++ + PD +LVEIVK ++ H+ G R N+ L
Sbjct: 562 KRETEDNSLAEVVREYMKRGYPELRPD--LILVEIVKNNLII---VHSPFGSRGNNTLGA 616
Query: 677 AFAYLISKRKRCNV-------GMAITDNGFMLKVPRDKELSQEEVLELFQVENLRETLKR 729
+ ++ K+ +AI+ +L + ++ L ++ + E LK+
Sbjct: 617 IISVMLDVEKQTKTTYRADPYHIAISS---VLPITKNDMEKIVSTLNSTPIDRIIEILKK 673
Query: 730 ALDNTELLKRRFRHVANRGLLVLRRY--MGRKKSLSRQQMNAQTLLNFLKRNYPEFPLLK 787
+ + K + L+ ++R+ + +K + TL + + + Y + + +
Sbjct: 674 GIKESPQFKWKL-------LVEIKRFGMIDPEKEI--------TLTSSIIKAYGDTIIGE 718
Query: 788 EVYREILEDKMDIENAELFLKWIKEGKVKIV 818
E +E+L D+E +K +K KIV
Sbjct: 719 EAVKELLVKNYDVE----IIKELKNYNWKIV 745
>pir||G72526 hypothetical protein APE2188 - Aeropyrum pernix (strain K1)
>gi|5105887|dbj|BAA81199.1| (AP000063) 977aa long
hypothetical protein [Aeropyrum pernix]
Length = 977
Score = 277 bits (702), Expect = 3e-73
Identities = 249/822 (30%), Positives = 391/822 (47%), Gaps = 93/822 (11%)
Query: 33 FKSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAIISELISLGRRGKLEDK--IYC 90
+KS P Q A I++G N L+ +PTGSGKT +A +++ L R G++ +
Sbjct: 48 YKSLLPIQEKAFPIIYRGLNALVVAPTGSGKTEAALAPLLARL----RNGRVASGGGVKV 103
Query: 91 VYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRTSDTSSYEKSKMLKMPP 150
VYV+PLRALN D+ +E + V VR DT + + L+ PP
Sbjct: 104 VYVTPLRALNRDLEGRVERLAG------------LFGYTVQVRHGDTVQSSRRRFLERPP 151
Query: 151 HILITTPESLAIALNAPRFREKLRDVKWVIVDEVHALAENKRGSHLALTLERLRELTKRD 210
I+ITTPESLA+ L R +E L+ + V+VDE+H L E+KRG L+L LE+L + R
Sbjct: 152 DIVITTPESLALLLTVKRAKEVLKQARAVVVDEIHELMESKRGVELSLNLEKLELMAGRR 211
Query: 211 FVRIGLSATI--HPLEEVAKFVFGFSDDGKPRPGLIVDVSFAKKTKITVESVVEDLVYTP 268
RIGLSAT+ H L A + G R +V + K+ + V V ++ +
Sbjct: 212 LQRIGLSATVSRHSLYRAASLL------GAGRHVSMVLDTSPKEYDVRVVVVGDEGRFWE 265
Query: 269 ANVLNEALYRRIGELVRSR-KTTLIFTNTRSGAERVAYHLKKMFPEWEDKIEAHHSSLSR 327
+V + I ELV+ + LIF NTRS E +A+ L + E +++ AHH SLSR
Sbjct: 266 NSV------KAIAELVKGEGGSVLIFANTRSTVETLAFALSR---ELGEEVPAHHGSLSR 316
Query: 328 EVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILIGSPKSVNRALQRIGRAGHRLH 387
VR VE K G +K IV+++SLELGID+G + LV+ SP+ V +QR GR+GHR
Sbjct: 317 HVRERVERDFKEGRVKAIVATSSLELGIDVGRVALVVQFLSPRQVTAMVQRAGRSGHRFG 376
Query: 388 EVSEGVILALDR-DDLVEVTVLAHNARKRKLDRIKIPKNPLDVLVQHLLGMALE-RVWEV 445
E S VI+ +D +++E V+A A K L+ I IPK P D L + G A++ +
Sbjct: 377 ERSRAVIVTIDNVFEVLESHVIAFRAMKGDLEDISIPKKPYDALAHFMAGAAIDSEPPTL 436
Query: 446 EEAYKVVRRAYPYHDLPFEDFINVLKYLAGEFSGLEERKVYAKIWLENGKFGKRGKMTRA 505
E YK+ PY DL E+ + + L+ + +V + G GK G+ +R
Sbjct: 437 EGVYKLAVSTAPYEDLKMEEVEEIARVLS-------DVRV-----IRLGPGGKLGRSSRT 484
Query: 506 I-YYMNTGTIPDEAKIDVF-TMDKKYIGTVEEEFAE-RLIPGD------IFVLAGRTYEF 556
Y+ IPDE V + + +G V E F + RL+ VL G+ ++
Sbjct: 485 YSYFYRVSMIPDEKTFKVHDVVSGRDVGEVGERFIQLRLMKASDPRSKPYIVLGGKVWKI 544
Query: 557 --VKSRGNKIYVIPREGVKPTIPSWFSEMLPLSFDLALDIQKFRREVKSLLNDEDAELKL 614
V K+ V P V+ IP+W E++P+ F +A ++ + +ND +A +L
Sbjct: 545 LEVDIDAGKVLVSPEGEVEGAIPAWEGELIPVDFKVAREVCSI---MSLAMNDMEAGARL 601
Query: 615 MEKYGIDEITAKAIISYFREQANY--SVIPDDETVLVEIVKEGNVVKYFFHTLIGRRAND 672
+ +DE + ++ E +V+ V+ E EG + Y +G R N
Sbjct: 602 LRARRLDEKAMERVLDVLGETGRLWGTVLSWRRPVVEE--AEGLAILY---ACLGSRGNF 656
Query: 673 ALSRAFAYLISKRKRCNVGMAI--TDNGFMLKVPRDKELSQEEVLELFQVENLRETLKRA 730
ALS L+SK +V + + K P + L + V + +TL +
Sbjct: 657 ALS----LLLSKLMEGSVAVEFHYIPYAIVFKSPASRGLGR-------LVAHSLKTLAK- 704
Query: 731 LDNTELLKRRFRHVANRGLLVLRRYMGRKKSLSRQQMNAQTLLNFLKRNYPEF---PLLK 787
L+ E L + V ++R Y K+ + +A L+ +++ P+
Sbjct: 705 LEPAERLGMLYDAVRRSRAYLVRFYQVAKR-MGVVDPDATLSLDIIRKMADAMQGTPVDI 763
Query: 788 EVYREILEDKMDIENAELFLKWIKEGKVKIVVEEHSYPSPFA 829
E +E++ +K+DI+ FL + + + V E SP A
Sbjct: 764 ETVKELVHEKLDIDALNRFLDDVSD----VAVVELQRLSPLA 801
>gb|AAK41239.1| ATP-dependent helicase [Sulfolobus solfataricus]
Length = 933
Score = 266 bits (672), Expect = 9e-70
Identities = 221/818 (27%), Positives = 399/818 (48%), Gaps = 90/818 (11%)
Query: 21 LDPIVREWFKRK-FKSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAIISELISLG 79
LD +R+ + K + T Q + I G N L+ +PTG GKT +A L I++ ++
Sbjct: 5 LDQRLRKLIEEKNWMKLTRVQEMSFEPISNGYNTLVIAPTGYGKTEAALLPILNRMLK-- 62
Query: 80 RRGKLED--KIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRTSDT 137
ED + +Y++PL+AL ND+ ++ + L + E+P+
Sbjct: 63 -----EDVKPVTVIYITPLKALINDLLYRIDWWASRLGFLVNRKHGEVPQ---------- 107
Query: 138 SSYEKSKMLKMPPHILITTPESLAIALN-APRFREKLRDVKWVIVDEVHALAENKRGSHL 196
EK+ LK PHI++TTPE L I L+ A RFRE ++VKWV+VDE+H L +KRG+ L
Sbjct: 108 --KEKNLRLKRIPHIIVTTPEGLEIDLDWASRFREHYKNVKWVVVDEIHELINSKRGTQL 165
Query: 197 ALTLERLRELTKRDFVRIGLSATIHPLEEVAKFVFGFSDDGKPRPGLIVDVSFAKKTKIT 256
++ LERL+ DF RIGLSAT+ ++VA+F+FG S+ R I+ ++ + +I
Sbjct: 166 SILLERLKYFIGYDFQRIGLSATVSDEDKVAQFLFGSSE----RKMKIIRLNDTRNFEIK 221
Query: 257 VESVVEDLVYTPANVLNEALYRRIGELVRSRKTTLIFTNTRSGAERVAYHLKKMFPEWED 316
+ + D + L ++ +I +L+ K TL+FTN+R ER+ L+K+
Sbjct: 222 INKLGNDNSF----ALWKSAAEKINQLI--EKPTLVFTNSRFSTERLHEELEKL---GNK 272
Query: 317 KIEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILIGSPKSVNRAL 376
+I HHSS+SR+++ E L+ G K +V + +LELGI +G I VI++ P SV+ L
Sbjct: 273 EIYVHHSSVSRDLKNLAEGELRNGNAKAVVCTKTLELGIHVGDIKKVIMLRPPTSVSSFL 332
Query: 377 QRIGRAGHRLHEVSEGVILALDRDDLVEVTVLAHNARKRKLDRIKIPKNPLDVLVQHLLG 436
QR+GR+GH +H V +G I+ D++E L +A+ K+++ I + LDV+ + ++G
Sbjct: 333 QRLGRSGHIVHGVPKGEIICFYDFDVLESLALYLSAKDGKMEKPFI-DDGLDVVAREIVG 391
Query: 437 MALE-RVWEVEEAYKVVRRAYPYHDLPFEDFINVLKYLAG------EFSGLEERKVYAKI 489
M L+ + +EE + ++R Y Y +L ++++ YL E + L+ + + KI
Sbjct: 392 MILQNQKMSIEEIFNIIRGTYIYRNLELSKLLDLVNYLVKNNIIKIEENYLKLGQGFFKI 451
Query: 490 WLENGKFGKRGKMTRAIYYMNTGTIPDEAKIDVFTMDKKYIGTVEEEFAERLI-PGDIFV 548
W +F + K + + ++ + + + +G ++ + + + DI
Sbjct: 452 W----RFNRDAKNSWGKDFSEFFSLINNDETFSLKHNGITVGEIDAVYVYKHVRANDIIR 507
Query: 549 LAGRTYEF--VKSRGNKIYVIPREGVKPTIPSWFSEMLPLSFDLALDIQKFRREVKSLLN 606
++G+ ++ + N I V P + IP W E + S + I+K
Sbjct: 508 ISGKFWKVLRINMHKNTIDVTPANEGEGEIPIWKGENMSKSPLIVNYIRKIMENFN---- 563
Query: 607 DEDAELKLMEKYGIDEITAKAIISYFREQANYSV-IPDDETVLVEIVKEGNVVKYFFHTL 665
E L +D+ + ++II F + IP + +LVE ++ ++ + +
Sbjct: 564 ----EYYLTMNEIMDKNSKESIIKIFENYRKLGLKIPSRDVILVENKED----EWLYTVV 615
Query: 666 IGRRANDALSRAFAYLISKRKRCNVGMAITDNGFMLKVPRDKELSQEEVLELFQVENLRE 725
I R ++ LS YL++K+ N + GF +K ++LF+
Sbjct: 616 IDERISNTLSHILLYLVTKKYTLNASSRSSIYGFSIK---------GTPVDLFK------ 660
Query: 726 TLKRALDNTELLKRRFRHVANRGLLVLRRYMGRKKSLSRQQMNAQTLLNFLKRNYPEFPL 785
D + R+ + R +L Y+ K + + + +N + + L
Sbjct: 661 ------DIINMNDRKIIKIILRSILRSPLYIATLKEI-QPSFGKISKINTKEDKF----L 709
Query: 786 LKEVYREILEDKMDIENAELFLKWIKEGKVKIVVEEHS 823
+KE R+ ++ I+ F++ ++EGK+KIV E++
Sbjct: 710 IKEALRQTIKRYFTIKKTLEFIRRVREGKIKIVYTENA 747
>pir||A69140 ATP-dependent helicase - Methanobacterium thermoautotrophicum
(strain Delta H) >gi|2621366|gb|AAB84818.1| (AE000816)
ATP-dependent helicase [Methanobacterium
thermoautotrophicum]
Length = 702
Score = 182 bits (457), Expect = 2e-44
Identities = 190/677 (28%), Positives = 313/677 (46%), Gaps = 98/677 (14%)
Query: 21 LDPIVREWFKRK--FKSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAIISELISL 78
L+P +R + + ++S Q+ A+ I +GE+ LI +PT SGKT +A + + + ++S
Sbjct: 6 LNPRLRHFLANRLGWRSLRDVQKSALEAIGRGEDTLIVAPTASGKTEAALIPVFNSILSE 65
Query: 79 GRRGKLEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRTSDTS 138
G + +YVSPL+AL ND+ LE N E+ + D
Sbjct: 66 GL-----PPVSMLYVSPLKALINDMHSRLEL-------WGNHFNLEVMKWH-----GDVP 108
Query: 139 SYEKSKMLKMPPHILITTPESLAIALNAPRFREKLR---DVKWVIVDEVHALAENKRGSH 195
+ K + +K P IL+ TPESL + + EK R +++++IVDE+H E RG
Sbjct: 109 ANRKRRFIKNPSDILLITPESLEVMMINRSRAEKERILGNLRYIIVDEIHQFIEADRGVQ 168
Query: 196 LALTLERLRELTKRDFVRIGLSATIHPLEEVAKFVFGFSDDGKPRPGLIVDVSFAKKTKI 255
L L RL T RIGLSAT+ EEV ++ P ++ D
Sbjct: 169 LNSLLARLERYTGVRPQRIGLSATVGNPEEVLNWM-------SPSGAVVRD--------- 212
Query: 256 TVESVVEDLVYTPANVLNEALYRRIGELVR--SRKTTLIFTNTRSGAERVAYHLKKMFPE 313
T E ++ ++ E + ++ E++R + K LIF +R AE+ ++K
Sbjct: 213 TAERKLQYRIF-------ELNHHKLIEVLRRFTGKKVLIFVPSRRDAEKYYNIIRKCL-- 263
Query: 314 WEDKIEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILIGSPKSVN 373
+ + HHSS++R+ R E EER + +V++++LELGID+G ID+VI I SP SVN
Sbjct: 264 -DVDVFIHHSSINRDSREEAEERFRSVSAAFMVNTSTLELGIDVGDIDVVIHIRSPTSVN 322
Query: 374 RALQRIGRAGHRLHEVSEGVILALDRDDLVEVTVLAHNARKRKLDRIKIPKNPLDVLVQH 433
R LQR GR+G R + I+ +++ L ++V A A +L+ ++IP PLD+
Sbjct: 323 RFLQRTGRSGRR--RGLQRTIIFQEKEALTALSV-ASLALSGRLEDLRIPVRPLDIYFHQ 379
Query: 434 LLGMALERVWEVE-----EAYKVVRRAYPYHDLPFEDFINVLKYLAGEFSGLEERKVYAK 488
+ L V+E+E + Y+ + RA+ + DL +DF ++++++ + +V+
Sbjct: 380 I----LSSVFELEKPTPGDIYRGLGRAHVFSDLDADDFRHLVEFMVEN----DFLRVHGP 431
Query: 489 IWLENGKFGKR-GKMTRAIYYMNTGTIPDEAKIDVFTMDKKYIGTVEEEFAERLIP-GDI 546
F K GKM +Y P + V K IG+++ F + G
Sbjct: 432 YIHHGFNFEKTFGKMNFLEFYT---VFPPNYEFTV-KHRTKVIGSLDSFFVVTYLKVGRG 487
Query: 547 FVLAGRTYEFVKSRGNKIYVIPREGVKP-----TIPSWFSEMLPLSFDLALDIQKFRREV 601
F+L G + VK ++ +++ VKP IP W S P +F++A R
Sbjct: 488 FILGGEKW-VVKDIDHERFIV---RVKPCTRDAEIPDWSSGGAPTTFEVA------RHVY 537
Query: 602 KSLLNDEDAELKLMEKYGIDEITAKAIISYFREQANYSVIPDDETVLVEIVKEGNVVKYF 661
LL D D L G + E ++ +IP V+ G ++
Sbjct: 538 DILLGDFDRGLLRWLDPGSQARVQSCMEMASAEGLDHGMIP---------VRIGERIE-- 586
Query: 662 FHTLIGRRANDALSRAF 678
+T G R N +S F
Sbjct: 587 INTFAGERVNALISDVF 603
>pir||T35049 probable ATP-dependent helicase - Streptomyces coelicolor
>gi|3483040|emb|CAA20551.1| (AL031371) putative
ATP-dependent helicase [Streptomyces coelicolor A3(2)]
Length = 731
Score = 153 bits (382), Expect = 9e-36
Identities = 129/444 (29%), Positives = 209/444 (47%), Gaps = 36/444 (8%)
Query: 11 EYSDEEIYSILDPIVREWFKRK--FKSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAF 68
E ++ LDP+V + P QR AI + +GE+ ++ +PT GKT +A
Sbjct: 9 ETEGADVLDRLDPVVLHHIVNTLGWSDLRPLQRAAITPLMEGEDAVLLAPTAGGKTEAAC 68
Query: 69 LAIISELISLGRRGKLEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEI 128
++S + G +Y+ PL+AL N++ ++ Q +
Sbjct: 69 FPLLSAMAEQKWTGTS-----VLYLCPLKALLNNLVSRVDTYTQWLGR------------ 111
Query: 129 RVAVRTSDTSSYEKSKMLKMPPHILITTPESLAIALNAPR--FREKLRDVKWVIVDEVHA 186
R A+ DT ++ ++ P +L+TTPESL L + L V+ V+VDEVHA
Sbjct: 112 RAALWHGDTKESQRQRIRTEAPDVLLTTPESLEAMLIGVKTDHARLLGSVRAVVVDEVHA 171
Query: 187 LAENKRGSHLALTLERLRELTKRDFVRIGLSATIHPLEEVAKFVFGFSDDGKP----RPG 242
A + RG HL LERL ++T R RIGLSAT+ +++ ++ G + + PG
Sbjct: 172 FAGDDRGWHLLAVLERLEQVTGRPIQRIGLSATVGNPDQLLDWLQGAGVETRAGRVVAPG 231
Query: 243 LIVDV-----SFAKKTKITVESVVEDLVYTPANVLNEALYRRIGELVRSRKTTLIFTNTR 297
+ + S K T V ++ L+ A + I L R K L+F ++R
Sbjct: 232 VTLPAFEAVGSDRKPTAEEVPRPAGEVELDYVGSLDNAA-KLIATLHRGEKR-LVFCDSR 289
Query: 298 SGAERVAYHLKKMFPEWEDKIEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDI 357
+ E++ L+ E + H+SLS + R E+ +IVS+++LELGID+
Sbjct: 290 AQVEQLGAALRAR----EVTVFLSHASLSVDERTRSEQAFAEARDCVIVSTSTLELGIDV 345
Query: 358 GTIDLVILIGSPKSVNRALQRIGRAGHRLHEVSEGVILALDRDDLVEVTVLAHNARKRKL 417
G +D VI I SP +V LQRIGR G R V + L +D L++ L + +
Sbjct: 346 GDLDRVIQIDSPATVASFLQRIGRTGRRAGTVRNCLFLTTRKDTLLQAAGLLLLWSRGWV 405
Query: 418 DRIKIPKNPLDVLVQHLLGMALER 441
+ +K P P ++ Q LL + L++
Sbjct: 406 EPVKPPPEPRHLVAQQLLAVTLQQ 429
>gb|AAK40384.1| ATP-dependent helicase [Sulfolobus solfataricus]
Length = 739
Score = 151 bits (378), Expect = 3e-35
Identities = 125/400 (31%), Positives = 198/400 (49%), Gaps = 47/400 (11%)
Query: 46 EIHKGENVLISSPTGSGKTLSAFLAIISELISLGRRGKLEDKIYCVYVSPLRALNNDIRR 105
+I ENV+I S TG+GKT AFL I +L G R V V P +AL D
Sbjct: 66 KIKNKENVMIISGTGTGKT-EAFLIPILDLALKGERS--------VLVYPTKALARD--- 113
Query: 106 NLEEPLQEIRELSQELNEEIPEIRVAVRTSDTSSYEKSKMLKMPPHILITTPESLAIALN 165
L + +L++EL + V + DT E+ ++ + PPHILIT P+ + + L
Sbjct: 114 ----QLTRVYKLARELG-----LNVGIFDGDTPEKERERLYRNPPHILITNPDMIHLGLA 164
Query: 166 -APRFREKLRDVKWVIVDEVHALAENKRGSHLALTLERLRELTKRDFVRIGLSATIHPLE 224
+ RFR LR I DEVH E G+H+ +R++E K D + SAT+ +
Sbjct: 165 LSTRFRFLLRTADHFIFDEVHVY-EGVLGAHIRNLADRIKEF-KNDIHIVASSATVGATK 222
Query: 225 EVAKFVFGFSDDGKPRPGLIVDVSFAKKTKITVESVVEDLVYTPANVLNEALYRRIGE-L 283
+ + +FG G I++ ++ I + S+++ N L + L
Sbjct: 223 YLFEELFGVE-------GEIIE-GIRRRKGIAIHSIIDS-----GNSSRWTLAAYLAAVL 269
Query: 284 VRSRKTTLIFTNTRSGAERVAYHLKKMFPEWEDKIEAHHSSLSREVRLEVEERLKRGELK 343
V++ L+FT+++ AE VA K+ + +E H + L E R++VEE+L+ GEL
Sbjct: 270 VKNGLKVLVFTDSQQMAELVA----KIADRFRVNLEVHRAGLIAEERIKVEEKLRNGELD 325
Query: 344 IIVSSTSLELGIDIGTIDLVILIGSPKSVNRALQRIGRAGHRLHEVSEGVILALDRDDLV 403
+V++ +LELGIDIGTID VI+ +P S + +QR GRAG R + G++ + DD +
Sbjct: 326 GVVATPTLELGIDIGTIDAVIMAENPPSYTKYVQRAGRAGRR---NNAGLVFTILGDDPI 382
Query: 404 EVTVLAHNAR--KRKLDRIKIPKNPLDVLVQHLLGMALER 441
+ L H RK+ + ++V+ H L E+
Sbjct: 383 DSYYLRHPEEFFTRKIQALTFDPTNIEVIKIHALAYLAEK 422
>pir||F71092 ATP-dependent RNA helicase homolog PH1003 - Pyrococcus horikoshii
>gi|3257417|dbj|BAA30100.1| (AP000004) 873aa long
hypothetical helicase [Pyrococcus horikoshii]
Length = 873
Score = 132 bits (329), Expect = 2e-29
Identities = 150/574 (26%), Positives = 252/574 (43%), Gaps = 102/574 (17%)
Query: 25 VREWFKRKFKSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAIISELISLGRRGKL 84
V E KR Q A+ ++ G+NV++S+PT SGK+ L I +
Sbjct: 36 VNELVKRLGFRLYSHQVKALNLLYSGKNVVVSTPTASGKSEIFRLFIFDSFLE------- 88
Query: 85 EDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRTSDTSSYEKSK 144
+ V P RAL N+ + + E++ +++ ++ T D E+ K
Sbjct: 89 NPSSTFLLVYPTRALINNQMEKFDNENKVFAEITGM------KVKASILTGDVDWSERKK 142
Query: 145 MLKMPPHILITTPESLAIALNAPRFREK---LRDVKWVIVDEVHALAENKRGSHLALTLE 201
+++ P+++ TTP+ L + PR+ E L+++K ++VDE+H GS++A
Sbjct: 143 IVRNKPNVIFTTPDMLHHTI-LPRWLEYKWLLKNLKLLVVDELHTY-RGVFGSNVAYVFR 200
Query: 202 R----LRELTKRDFVRIGLSATIHPLEEVAKFVFGF-----SDDGKPRPGLIVDVSFAKK 252
R LR L + + LSAT+ +E A+ FGF ++ G P P +
Sbjct: 201 RVFFRLRRLNSSPLI-LALSATLRNPKEFAESFFGFEFEEVTEAGNPSPRRYI------- 252
Query: 253 TKITVESVVEDLVYTPANVLNEALYRR-IGELVRSRKTTLIFTNTRSGAERVAYHLKKMF 311
+++ P E L ++ I +L+R+ TL+F ++R G ER+ +F
Sbjct: 253 -----------IMFEPKRFSGEQLIKQVIDKLIRNNVKTLVFFDSRKGTERIMRMF--LF 299
Query: 312 PEWEDKIEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILIGSPK- 370
E+ DKI + +L++ R ++E + G LK+++++ +LELGID+G +D VI G P
Sbjct: 300 SEFFDKITTYKGTLTKLERWKIERDFREGNLKVLLATNALELGIDVGDLDAVINYGIPSD 359
Query: 371 SVNRALQRIGRAGHRLHEVS-EGVIL---ALDRDDLVEVTVLAHNARKRKLDRI------ 420
+ +QR GRAG + V+ G+IL LD L K +D+I
Sbjct: 360 GLFSLIQRFGRAGRDPNRVAINGIILRKNGLDYYYKEHFDELVEGIEKGLVDKIPVNLGN 419
Query: 421 -KIPKNPLDVLVQHLLGMALERVWEVEEAYKVVRRAYPYHDLPFEDFINVLKY-LAGEFS 478
KI K L L+ L + + E+ E + V DL E ++ K + G+F
Sbjct: 420 EKIAKKHLHYLLSELGVVGKD---EIPEYWVKV-----LEDLKHEGIVDEYKNPITGKFE 471
Query: 479 -GLEERKVYAKI---------------WLENGKFGKRG-KMTRAIYYMNT-GTIPDEAKI 520
+ + VY+ I W+ KRG ++ R I Y+ G I +E
Sbjct: 472 VRVRKPAVYSSIRTASDESFFLVIDEGWIRRTLRRKRGIELLRFINYLKARGLIIEEVD- 530
Query: 521 DVFTMDKKYIGTVEEEFAERLIPGDIFVLAGRTY 554
E EF L+PG ++ GR Y
Sbjct: 531 -------------EVEFHRSLLPGMVYPSRGRLY 551
>pir||E64496 ATP-dependent RNA helicase homolog MJ1574 - Methanococcus
jannaschii >gi|1592195|gb|AAB99590.1| (U67597)
ATP-dependent RNA helicase, eIF-4A family, putative
[Methanococcus jannaschii]
Length = 684
Score = 126 bits (314), Expect = 9e-28
Identities = 112/402 (27%), Positives = 201/402 (49%), Gaps = 48/402 (11%)
Query: 6 KWANREYSDEEIYSILDPIVREWFKRKFKSFTPPQRYAIVEIHKGENVLISSPTGSGKTL 65
+++N ++ ++EI ++D + + + + K A+ ++ ++V++++ T SGK+
Sbjct: 24 RFSNFKFKNKEINELIDALGFKLYLHQVK--------ALKYLYNKKDVVVTTSTASGKSE 75
Query: 66 SAFLAIISELISLGRRGKLEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEI 125
LAI +S +D+ +Y P RAL N N E EL ++ +
Sbjct: 76 IFRLAIFDNFLS-----NPDDRYLLIY--PTRALIN----NQYEKFSMENELFYKITNK- 123
Query: 126 PEIRVAVRTSDTSSYEKSKMLKMPPHILITTPESL--AIALNAPRFREKLRDVKWVIVDE 183
++ + T D ++ ++LK P++L TTP+ L I N + L+++K ++VDE
Sbjct: 124 -RVKAEILTGDVGLEKRREILKDKPNVLFTTPDMLHYQILKNHNNYLWLLKNLKLLVVDE 182
Query: 184 VHALAENKRGSHLALTLERLRELTKR---DFVRIGLSATIHPLEEVAKFVFGFSDDGKPR 240
+H G+++ +RL +L KR + + LSAT+ +E K +F R
Sbjct: 183 LHVY-RGVFGTNMVYVFKRLLKLLKRLNNNLQILCLSATLKNPKEFVKLLFN-------R 234
Query: 241 PGLIVDVSFAKKTKITVESVVEDLVYTPANVLNEALYRRIGE-LVRSRKTTLIFTNTRSG 299
+VD S+ ++ + + P N+ N+ L RR+ E LV + TL+F +TR
Sbjct: 235 DFEVVDKSYNPSSRKYLA------ILEPKNLDNKQLLRRLIENLVDNNIKTLVFFDTRKE 288
Query: 300 AERVAYHL--KKMFPEWEDKIEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDI 357
E++ L K+F K+ + +L + VR E+EE+ K GE+ ++++ +LELGIDI
Sbjct: 289 TEKLMRFLLNSKVFY----KLSTYKGTLPKYVREEIEEKFKNGEILALLTTNALELGIDI 344
Query: 358 GTIDLVILIG-SPKSVNRALQRIGRAGHRLHEVSEGVILALD 398
G +D VI G P + +QR GRAG R E ++L D
Sbjct: 345 GDLDAVINYGIPPDGIFSLIQRFGRAGRRDKEALNIIVLRKD 386
>sp|P50830|YPRA_BACSU HYPOTHETICAL HELICASE IN PONA-COTD INTERGENIC REGION
>gi|7446091|pir||B69941 ATP-dependent RNA helicase
homolog yprA - Bacillus subtilis
>gi|1146178|gb|AAB38468.1| (L47838) helicase [Bacillus
subtilis] >gi|2634641|emb|CAB14139.1| (Z99115) similar
to ATP-dependent helicase [Bacillus subtilis]
Length = 749
Score = 121 bits (300), Expect = 4e-26
Identities = 111/436 (25%), Positives = 201/436 (45%), Gaps = 49/436 (11%)
Query: 30 KRKFKSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAIISELISLGRRGKLEDKIY 89
KR Q A + KGE+++ +PT SGKTL L ++ + ++
Sbjct: 49 KRGIDELYTHQYSAFQYVQKGESIVTVTPTASGKTLCYNLPVLQSIAQ-------DETNR 101
Query: 90 CVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRT----SDTSSYEKSKM 145
+Y+ P +AL D + ELNE I E+ + +++ DTS + K+
Sbjct: 102 ALYLFPTKALAQDQK--------------SELNEIIDEMGIDIKSFTYDGDTSPAIRQKV 147
Query: 146 LKMPPHILITTPESL--AIALNAPRFREKLRDVKWVIVDEVHALAENKRGSHLALTLERL 203
K HI+IT P+ L AI + ++ ++K++++DE+H GSH+A + RL
Sbjct: 148 RKAG-HIVITNPDMLHSAILPHHTKWVSLFENLKYIVIDELHTY-RGVFGSHVANVIRRL 205
Query: 204 RELTK---RDFVRIGLSATIHPLEEVAKFVFGFSDDGKPRPGLIVDVSFAKKTKITVESV 260
+ + + D V I SATI +E+ + + G +P +VD + A +
Sbjct: 206 KRICRFYGSDPVFICTSATIANPKELGEQLTG-------KPMRLVDDNGAPSGRKHFVFY 258
Query: 261 VEDLVYTPANVLNEA---LYRRIGELVRSRKTTLIFTNTRSGAERVAYHLKKMFPE--WE 315
+V P N+ A + E ++++ T++F +R E + H++++ +
Sbjct: 259 NPPIVNKPLNIRRSATAEVNELAKEFLKNKVQTIVFARSRVRVEIILSHIQELVKKEIGT 318
Query: 316 DKIEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILIGSPKSVNRA 375
I + + R E+E L+ G++ +VS+ +LELG+DIG + + ++ G P SV A
Sbjct: 319 KSIRGYRGGYLPKERREIERGLREGDILGVVSTNALELGVDIGQLQVCVMTGYPGSVASA 378
Query: 376 LQRIGRAGHRLHEVSEGVILALDRDDLVEVTVLAHNAR--KRKLDRIKIPKNPLDVLVQH 433
Q+ GRAG R E +I+ + ++ ++ H R + +I L +LV H
Sbjct: 379 WQQAGRAGRR---HGESLIIMVANSTPIDQYIVRHPEYFFNRSPESARINPENLIILVDH 435
Query: 434 LLGMALERVWEVEEAY 449
L A E + +E +
Sbjct: 436 LKCAAYELPFRADEEF 451
>gi|6320497 Ydr291wp [Saccharomyces cerevisiae] >gi|2131417|pir||S70120
ATP-dependent RNA helicase homolog YDR291w - yeast
(Saccharomyces cerevisiae) >gi|1230655|gb|AAB64466.1|
(U51031) Ydr291wp [Saccharomyces cerevisiae]
Length = 1077
Score = 114 bits (283), Expect = 4e-24
Identities = 109/395 (27%), Positives = 187/395 (46%), Gaps = 47/395 (11%)
Query: 34 KSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAIISELISLGRRGKLEDKIYCVYV 93
++F Q AI +H+GENV+I++ T SGK+L LA I L+ + + +Y+
Sbjct: 289 ENFYSHQADAINSLHQGENVIITTSTSSGKSLIYQLAAIDLLLK-------DPESTFMYI 341
Query: 94 SPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRTSDTSSYEKSKMLKMPPHIL 153
P +AL D +R + L +I EL + V DT E++ + K ++
Sbjct: 342 FPTKALAQDQKRAFKVILSKIPELKNAV--------VDTYDGDTEPEERAYIRKNA-RVI 392
Query: 154 ITTPESL--AIALNAPRFREKLRDVKWVIVDEVHALAENKRGSHLALTLERLRELTKRDF 211
T P+ + +I N +R L +K V+VDE+H + + GSH+AL + RL L +
Sbjct: 393 FTNPDMIHTSILPNHANWRHFLYHLKLVVVDELH-IYKGLFGSHVALVMRRLLRLCHCFY 451
Query: 212 VRIGL-----SATIHPLEEVAKFVFGFSD------DGKPRPGLIVDVSFAKKTKITVESV 260
GL SAT+ + K +FG ++ DG P + AK + +
Sbjct: 452 ENSGLQFISCSATLKSPVQHMKDMFGINEVTLIHEDGSP--------TGAKHLVVWNPPI 503
Query: 261 VEDLVYTPANVLNEALYRRIGELVRSRKTTLIFTNTRSGAERVAYHLKKMFPEW--ED-- 316
+ N + E+ + + +L+ + T+ F R E + ++ +F E ED
Sbjct: 504 LPQHERKRENFIRESA-KILVQLILNNVRTIAFCYVRRVCELLMKEVRNIFIETGREDLV 562
Query: 317 -KIEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILIGSPKSVNRA 375
++ ++ S R ++E + G LK ++S+ +LELGIDIG +D V++ G P S+
Sbjct: 563 TEVMSYRGGYSASDRRKIEREMFHGNLKAVISTNALELGIDIGGLDAVLMCGFPLSMANF 622
Query: 376 LQRIGRAGHRLHEVSEGVILALDRDDLVEVTVLAH 410
Q+ GRAG R ++ + L + D V+ +AH
Sbjct: 623 HQQSGRAGRR---NNDSLTLVVASDSPVDQHYVAH 654
>dbj|BAB05483.1| (AP001513) ATP-dependent RNA helicase [Bacillus halodurans]
Length = 764
Score = 114 bits (283), Expect = 4e-24
Identities = 112/437 (25%), Positives = 204/437 (46%), Gaps = 50/437 (11%)
Query: 21 LDPIVREWF-KRKFKSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAIISELISLG 79
LD +RE KR Q A KGE+V+ +PT SGKTL L ++ ++
Sbjct: 43 LDIRIREALEKRGIGQLYTHQNTAYECSEKGEHVVAVTPTASGKTLCYNLPVLQQI---- 98
Query: 80 RRGKLEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQEL----NEEIPEIRVAVRTS 135
+ ++ +Y+ P +AL D + L E ++E+ +S + + P IR AVR +
Sbjct: 99 ---RRDESSRALYLFPTKALAQDQKSELNEIIEEMG-ISVKCFTYDGDTAPNIRQAVRKA 154
Query: 136 DTSSYEKSKMLKMPPHILITTPESL--AIALNAPRFREKLRDVKWVIVDEVHALAENKRG 193
H++IT P+ L AI + ++ ++K+V++DE+H G
Sbjct: 155 G--------------HVVITNPDMLHSAILPHHTKWVAFFENLKYVVIDELHTY-RGVFG 199
Query: 194 SHLALTLERLRELTK---RDFVRIGLSATIHPLEEVAKFVFGFSDDGKPRPGLIVDVSFA 250
SH+A + RL+ + + + I SATI +E+A + G + ++D + A
Sbjct: 200 SHVANVIRRLKRIARYYGSEPTFICTSATIANPQELASQLTGHNVR-------LIDNNGA 252
Query: 251 KKTKITVESVVEDLVYTPANVLNEA---LYRRIGELVRSRKTTLIFTNTRSGAERVAYHL 307
K +V P N+ A + R + + + T++F +R E + HL
Sbjct: 253 PSGKKHFVFYNPPVVNEPLNIRKSATVEVNRLAKKFLENNIQTIVFARSRVRVEVILSHL 312
Query: 308 KKMFPE--WEDKIEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVIL 365
+++ + + + + + R E+E L+ G++ +VS+ +LELG+DIG + + I+
Sbjct: 313 QELTKKKIGQQAVRGYRGGYLPKQRREIERGLRNGDIIGVVSTNALELGVDIGQLQVCIM 372
Query: 366 IGSPKSVNRALQRIGRAGHRLHEVSEGVILALDRDDLVEVTVLAH--NARKRKLDRIKIP 423
G P S+ A Q+ GRAG R H E + L + ++ ++ H ++ + ++I
Sbjct: 373 TGYPGSIASAWQQSGRAGRRQH---ESLTLLVAGSSPIDQYMIQHPDYFLEKSPESVRIN 429
Query: 424 KNPLDVLVQHLLGMALE 440
++ L +LV HL A E
Sbjct: 430 RDNLIILVDHLKCAAYE 446
>pir||B75073 ATP-dependent RNA helicase homolog PAB1722 - Pyrococcus abyssi
(strain Orsay) >gi|5458399|emb|CAB49887.1| (AJ248286)
SIMILAR TO SEVERAL DNA HELICASES [Pyrococcus abyssi]
Length = 872
Score = 112 bits (278), Expect = 1e-23
Identities = 142/598 (23%), Positives = 260/598 (42%), Gaps = 113/598 (18%)
Query: 43 AIVEIHKGENVLISSPTGSGKTLSAFLAIISELISLGRRGKLEDKIYCVYVSPLRALNND 102
A+ ++ G+NV++S+PT SGK+ L I E + + + + P RAL N
Sbjct: 53 ALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFLE-------DSSSTFLLIYPTRALIN- 104
Query: 103 IRRNLEEPLQEIRELSQELNEEIPEIRVAVRTSDTSSYEKSKMLKMPPHILITTPESLAI 162
N E + E+ ++ ++ ++ T D E+ ++ + P+++ TTP+ L
Sbjct: 105 ---NQLEKFERENEIFSKITGR--KVGNSILTGDVELSERRRIRREKPNVIFTTPDMLHY 159
Query: 163 ALNAPR---FREKLRDVKWVIVDEVHALAENKRGSHLALTLERLRELTKRDFVR---IGL 216
L PR ++ +++K ++VDE+H + GS++A RL +R V + L
Sbjct: 160 NL-LPRWLDYKWLFKNLKLLVVDELH-IYRGVFGSNVAYVFRRLFLRLRRLKVNPRILAL 217
Query: 217 SATIHPLEEVAKFVFGF-----SDDGKPRPGLIVDVSFAKKTKITVESVVEDLVYTPANV 271
SAT+ ++ A+ FGF ++ G P P + +++ P
Sbjct: 218 SATLKNPKDFAEKFFGFEFEEVTEAGNPSPKRYI------------------IMFEPTRF 259
Query: 272 LNEALYRRIGE-LVRSRKTTLIFTNTRSGAERVAYHL--KKMFPEWEDKIEAHHSSLSRE 328
E L R+I E LV + TL+F ++R G ER+ K+F + I + +L++
Sbjct: 260 SGEQLIRQIVERLVENDVKTLVFFDSRKGTERIMRMFLGSKVF----NLITTYKGTLTKL 315
Query: 329 VRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILIGSPK-SVNRALQRIGRAGHRLH 387
R +E + G+LK ++++ +LELGID+G +D VI G P + +QR GRAG +
Sbjct: 316 ERWRIESDFREGKLKALLTTNALELGIDVGDLDAVINYGIPSDGLFSLIQRFGRAGRDPN 375
Query: 388 EVS-EGVIL---ALDRDDLVEVTVLAHNARKR-------KLDRIKIPKNPLDVLVQHLLG 436
V+ G++L LD L K LD +I K L L+ L
Sbjct: 376 RVAINGIVLRRNGLDYYYKEHFEELVEGIEKGLVEGIPVNLDNERIAKKHLHYLLSEL-- 433
Query: 437 MALERVWEVEEAYKVVRRAYPYHDLPFEDFINVLKYLAGEFSGLEERKVYAKI------- 489
+ V E+ E +++ R + E+++N L +++ +Y+ I
Sbjct: 434 -GVVDVNEIPEHWRIALRPLKEEGI-VEEYLNPLTNKVE--IRIKKPAIYSSIRSTSDES 489
Query: 490 --------WLENGKFGKR-GKMTRAIYYMNT-GTIPDEAKIDVFTMDKKYIGTVEEEFAE 539
W+ + K G++ R + Y+ G I +E E EF
Sbjct: 490 FFLVKDEGWIRSSLVRKSGGELLRFVNYLKARGFIIEEVD--------------EVEFYR 535
Query: 540 RLIPGDIFVLAGRTYEFV-KSRGNKIYVIPREGVKPTIPSWFSEMLPLSFDLALDIQK 596
L+PG ++ GR + + K +K + + F++ +P++ D+ ++ K
Sbjct: 536 SLLPGMVYPSRGRLFMVIDKINVDKFHFV------------FAQEIPMNEDVETNVHK 581
>gi|11499982 ATP-dependent RNA helicase, putative [Archaeoglobus fulgidus]
>gi|7446072|pir||G69550 ATP-dependent RNA helicase
homolog AF2406 - Archaeoglobus fulgidus
>gi|2650686|gb|AAB91259.1| (AE001109) ATP-dependent RNA
helicase, putative [Archaeoglobus fulgidus]
Length = 766
Score = 109 bits (271), Expect = 1e-22
Identities = 120/448 (26%), Positives = 205/448 (44%), Gaps = 67/448 (14%)
Query: 10 REYSDEEIYSILDPIVREWFKRKFKSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFL 69
RE EE+ + + KR P Q+ A++ + +G +V+I++PTG GKT + +
Sbjct: 60 REKPTEELDFLPSELASCLRKRGIGRLYPFQKEAMIRLMEGRDVVITAPTGFGKTEAFAV 119
Query: 70 AIISELISLGRRGKLEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIR 129
++ + G+ + P +AL D ++I+ + L +R
Sbjct: 120 PMLWRALHGGK---------AMVFYPTKALARDQE-------EKIKFYTSSLG-----LR 158
Query: 130 VAVRTSDTSSYEKSKMLKMPPHILITTPESLAIAL-NAPRFREKLRDVKWVIVDEVHALA 188
D+ E+ +L I++T P+ + L N P FR R++ ++ VDE+H
Sbjct: 159 AVRFDGDSGREERRAVLSGKCDIILTNPDMVDYHLRNTPAFRRICRELSFIAVDELHTYT 218
Query: 189 ENKRGSHLALTLERLRELTKRDFVRIGLSATIHPLEEVAKFVFGFSDDGKPRPGLIVDVS 248
GS++ ++RL +F SAT+ E A+ +F R ++V
Sbjct: 219 -GVLGSNMHYLVKRLSRFA--EFQIACASATLSNAAEFAEELFD-------RDFVLVSGE 268
Query: 249 FAKKTKITVESVVEDLVYTPANVLNEALYRRIGELV---RSRKTTLIFTNTRSGAERVAY 305
K T + YTP+ LY + E+V R+RK ++F N+ E +
Sbjct: 269 HRKGTLHLI------FRYTPS------LYSAVREIVTALRNRKI-IVFGNSYKSVETINL 315
Query: 306 HLKKMFPEWEDKIEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVIL 365
L++ K H S L +EVR EVE + KRGE+ I+VS+ +LELG+DIG +D+V+
Sbjct: 316 ILRRHGL----KSAIHKSGLPKEVREEVEAKFKRGEINIVVSTPTLELGVDIGDVDVVVS 371
Query: 366 IGSPKSVNRALQRIGRAGHRLHEVSEGVILALDRDDLVEVTVLAHNARKRKLDRIK---- 421
P + +QR+GRAG + E S GV++ L DD + R + D K
Sbjct: 372 ELVP--YGQMIQRVGRAGRKGQE-SVGVVI-LREDDSISTYY-----RTKPEDYFKEEAN 422
Query: 422 --IPKNPLDVLVQHLLGMALERVWEVEE 447
+ ++ +V+ L+ M +E+ +EE
Sbjct: 423 GYVERHNEEVMKFQLISMCIEKPVRLEE 450
>pir||T43854 helicase [imported] - Pyrococcus furiosus
>gi|3374506|dbj|BAA32016.1| (AB016521) helicase
[Pyrococcus furiosus]
Length = 720
Score = 108 bits (267), Expect = 3e-22
Identities = 125/432 (28%), Positives = 191/432 (43%), Gaps = 97/432 (22%)
Query: 14 DEEIYSILDPIVREWFKRKFKSFTPPQRYAIVE-IHKGENVLISSPTGSGKTLSAFLAII 72
DE I S L +R +SF PPQ A+ I +G+N LIS PT SGKTL A +A++
Sbjct: 9 DERIKSTLK-------ERGIESFYPPQAEALKSGILEGKNALISIPTASGKTLIAEIAMV 61
Query: 73 SELISLGRRGKLEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAV 132
+++ G + VY+ PL+AL EE QE ++ E +RVA+
Sbjct: 62 HRILTQGGKA--------VYIVPLKAL-------AEEKFQEFQDW------EKIGLRVAM 100
Query: 133 RTSDTSSYEKSKMLKMPPHILITTPESLAIALNAPRFREKLRDVKWVIVDEVHALAENKR 192
T D S K + L I+ T + ++ + + ++DVK ++ DE+H + R
Sbjct: 101 ATGDYDS--KDEWLGKYDIIIATAEKFDSLLRHGSSW---IKDVKILVADEIHLIGSRDR 155
Query: 193 GSHLALTLERLRELTKRDFVRIGLSATIHPLEEVAKFVFG--FSDDGKP---RPGLIVDV 247
G+ L + L + L K IGLSATI EE+A+++ D +P R G+
Sbjct: 156 GATLEVILAHM--LGKAQI--IGLSATIGNPEELAEWLNAELIVSDWRPVKLRRGVFYQG 211
Query: 248 SFA-KKTKITVESVVEDLVYTPANVLNEALYRRIGELVRSRKTTLIFTNTRSGAERVAYH 306
+ I S E+LVY + +R +K LIF N R AERVA
Sbjct: 212 FVTWEDGSIDRFSSWEELVY---------------DAIRKKKGALIFVNMRRKAERVALE 256
Query: 307 LKKMFP------------EWEDKIEA-----------------HHSSLSREVRLEVEERL 337
L K E D +E HH+ L R+ R+ VEE
Sbjct: 257 LSKKVKSLLTKPEIRALNELADSLEENPTNEKLAKAIRGGVAFHHAGLGRDERVLVEENF 316
Query: 338 KRGELKIIVSSTSLELGIDIGTIDLVIL-------IGSPK-SVNRALQRIGRAGH-RLHE 388
++G +K +V++ +L GI+ ++I G + + Q +GRAG + E
Sbjct: 317 RKGIIKAVVATPTLSAGINTPAFRVIIRDIWRYSDFGMERIPIIEVHQMLGRAGRPKYDE 376
Query: 389 VSEGVILALDRD 400
V EG+I++ D
Sbjct: 377 VGEGIIVSTSDD 388
>pir||E71073 hypothetical protein PH1280 - Pyrococcus horikoshii
>gi|3257700|dbj|BAA30383.1| (AP000005) 715aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 715
Score = 104 bits (256), Expect = 6e-21
Identities = 118/428 (27%), Positives = 184/428 (42%), Gaps = 97/428 (22%)
Query: 14 DEEIYSILDPIVREWFKRKFKSFTPPQRYAIVE-IHKGENVLISSPTGSGKTLSAFLAII 72
DE I +L KR PPQ A+ I KGEN LI+ PT SGKTL A +AI+
Sbjct: 9 DERIKEVLK-------KRGISELYPPQAEALTSGILKGENALIAIPTASGKTLIAEIAIV 61
Query: 73 SELISLGRRGKLEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAV 132
+ L+ G + VY+ PL+AL EE +E ++ +EL ++VA+
Sbjct: 62 NRLLKEGGKA--------VYLVPLKAL-------AEEKFKEFKDW-EELG-----LKVAM 100
Query: 133 RTSDTSSYEKSKMLKMPPHILITTPESLAIALNAPRFREKLRDVKWVIVDEVHALAENKR 192
T D Y+ I+I T E L +R+VK ++VDE+H + R
Sbjct: 101 ATGD---YDSKDEWLGGYDIIIATAEKFDSLLR--HGSSWIRNVKVLVVDEIHLIGSRDR 155
Query: 193 GSHLALTLERLRELTKRDFVRIGLSATIHPLEEVAKFVFG--FSDDGKP---RPGLIVD- 246
G+ L + ++ + IGLSATI EE+A+++ D +P R G+
Sbjct: 156 GATLEFIITQMLNRAQI----IGLSATIGNPEELAEWLNAKLIKSDWRPVKLRRGVFYQG 211
Query: 247 VSFAKKTKITVESVVEDLVYTPANVLNEALYRRIGELVRSRKTTLIFTNTRSGAERVAYH 306
F + K + E+LVY + ++ K +L+F N R AE+ A
Sbjct: 212 FVFWEDGKTEKFNSWEELVY---------------DAIKRSKGSLVFVNMRRKAEKTALE 256
Query: 307 LKKMFPEWEDKIEA-----------------------------HHSSLSREVRLEVEERL 337
L K + K E HH+ L RE R+ VEE
Sbjct: 257 LSKKIRNFLTKKELRELKELAESLEENPTNEKLAKALQGGVAFHHAGLGREERVLVEENF 316
Query: 338 KRGELKIIVSSTSLELGIDIGTIDLVIL-------IGSPK-SVNRALQRIGRAGH-RLHE 388
K+G +K++V++ +L GI+ +++ G + + Q +GRAG + E
Sbjct: 317 KKGLIKVVVATPTLSAGINTPAFRVIVRDTWRYSEFGMERIPILEIQQMMGRAGRPKYDE 376
Query: 389 VSEGVILA 396
V E +I++
Sbjct: 377 VGEAIIVS 384
>pir||T36671 probable helicase - Streptomyces coelicolor
>gi|4539568|emb|CAB38487.1| (AL035636) putative helicase
[Streptomyces coelicolor A3(2)]
Length = 815
Score = 102 bits (251), Expect = 2e-20
Identities = 112/412 (27%), Positives = 191/412 (46%), Gaps = 47/412 (11%)
Query: 50 GENVLISSPTGSGKTLSAFLAIISELISLGRRGKLEDKIYCVYVSPLRALNNDIRRNLEE 109
G++V++++ T SGK+L+ + ++S L+ G +Y++P +AL D R+
Sbjct: 105 GDSVVVATGTASGKSLAYLVPVLSALVD-GSEAPNGRGATTLYLAPTKALAADQCRS--- 160
Query: 110 PLQEIRELSQELNEEIPEIRVAVRTSDTSSYEKSKMLKMPPHILITTPESL--AIALNAP 167
++ELSQ L + R AV DT +E+ + ++ ++T P+ L I + P
Sbjct: 161 ----VKELSQPLGTSV---RAAVYDGDTP-FEEREWIRQYGTYVLTNPDMLHRGILPSHP 212
Query: 168 RFREKLRDVKWVIVDEVHALAENKRGSHLALTLERLRELTKR---DFVRIGLSATIHPLE 224
R+ L+ +K+V++DE H GSH+A L RLR L R V + SAT
Sbjct: 213 RWSSFLKALKYVVIDECHTY-RGVFGSHVAQVLRRLRRLCARYGASPVFLLASATAAEPS 271
Query: 225 EVAKFVFGF-----SDDGKPRPGLIVDVSFAKKTKITVES---VVEDLVYTPANVLNEAL 276
A+ + G +DD PR L+ + T++ E V A++L +
Sbjct: 272 VAARRLTGLPVIEVADDASPRGELVFALWEPPLTELEGEKGAPVRRTATAEAADLLTD-- 329
Query: 277 YRRIGELVRSRKTTLIFTNTRSGAERVAYHLKKMFPEWE----DKIEAHHSSLSREVRLE 332
L ++ F +R GAE ++ ++ E + ++ A+ E R
Sbjct: 330 ------LTVQGMRSITFVRSRRGAELISVIAQERLAEVDRSLAGRVAAYRGGYLPEERRA 383
Query: 333 VEERLKRGELKIIVSSTSLELGIDIGTIDLVILIGSPKSVNRALQRIGRAGHRLHEVSEG 392
+E L G+L + ++ +LELG+DI +D V++ G P + Q+ GRAG R + +
Sbjct: 384 LERALHSGDLLGLAATNALELGLDISGLDAVVIAGYPGTRASLWQQAGRAG-RAGQGALA 442
Query: 393 VILALDRDDLVEVTVLAHNAR----KRKLDRIKIPKNPLDVLVQHLLGMALE 440
V++A RDD ++ T L H+ + + P NP VL HL A E
Sbjct: 443 VLVA--RDDPLD-TFLVHHPEALFDQPVESTVLDPDNPY-VLAPHLCAAAAE 490
>pir||B75135 DNA helicase related protein PAB0592 - Pyrococcus abyssi (strain
Orsay) >gi|5458306|emb|CAB49795.1| (AJ248285) DNA
HELICASE RELATED PROTEIN [Pyrococcus abyssi]
Length = 715
Score = 100 bits (246), Expect = 8e-20
Identities = 120/472 (25%), Positives = 200/472 (41%), Gaps = 87/472 (18%)
Query: 30 KRKFKSFTPPQRYAIVE-IHKGENVLISSPTGSGKTLSAFLAIISELISLGRRGKLEDKI 88
+R + PPQ A+ + +GEN+L++ PT SGKTL A +AI ++L+ G +
Sbjct: 18 ERGIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLEEGGK------- 70
Query: 89 YCVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRTSDTSSYEKSKMLKM 148
VY+ PL+AL EE +E ++ E ++VA+ T D Y+
Sbjct: 71 -AVYIVPLKAL-------AEEKFREFKDW------ERLGLKVAMATGD---YDSKDEWLG 113
Query: 149 PPHILITTPESLAIALNAPRFREKLRDVKWVIVDEVHALAENKRGSHLALTLERLRELTK 208
I+I T E L +RDVK +++DE+H + RG+ L + ++ +
Sbjct: 114 KYDIIIATAEKFDSLLR--HGSSWIRDVKMLVIDEIHLIGSRDRGATLEFIITQMLGRAQ 171
Query: 209 RDFVRIGLSATIHPLEEVAKFVFG--FSDDGKPRPGLIVDVSFAKKTKITVESVVEDLVY 266
IGLSATI EE+A+++ D +P V K ED
Sbjct: 172 ----IIGLSATIGNPEELAEWLNAKLIRSDWRP-------VKLRKGVFYQGFVFWEDGGS 220
Query: 267 TPANVLNEALYRRIGELVRSRKTTLIFTNTRSGAERVAYHLKKMFPEWEDKIEA------ 320
N E +Y + V+ K L+F N R AE+ A L K + D+ E
Sbjct: 221 ERYNSWEELVY----DAVKKGKGALVFVNMRRKAEKTALELAKKVKNYLDRKELRELREL 276
Query: 321 -----------------------HHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDI 357
HH+ L R+ R+ VE+ ++G +K++V++ +L GI+
Sbjct: 277 AESLEENPTNEKLAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINT 336
Query: 358 GTIDLVIL-------IGSPK-SVNRALQRIGRAGH-RLHEVSEGVILALDRDDLVEVTVL 408
++I G + V Q +GRAG R EV E +I++ E +++
Sbjct: 337 PAFRVIIRDTWRYSEFGMERIPVLEVQQMMGRAGRPRYDEVGEAIIVSTTE----EPSLV 392
Query: 409 AHNARKRKLDRIKIPKNPLDVLVQHLLGM-ALERVWEVEEAYKVVRRAYPYH 459
+ K K +++ + +L +L + A E +E Y + R + H
Sbjct: 393 IDHYIKGKPEKLFSQLSNESILRSQILALIATFGYSEFKEIYDFLERTFYAH 444
>pir||F69164 ATP-dependent RNA helicase homolog MTH492 - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2621563|gb|AAB84998.1| (AE000833) ATP-dependent RNA
helicase, eIF-4A family [Methanobacterium
thermoautotrophicum]
Length = 822
Score = 99.1 bits (243), Expect = 2e-19
Identities = 100/366 (27%), Positives = 170/366 (46%), Gaps = 53/366 (14%)
Query: 40 QRYAIVEIHKGENVLISSPTGSGKTLSAFLAIISELISLGRRGKLEDKIYCVYVSPLRAL 99
QR A+ I +G N+LI++PT SGKTL+ L I+ L L +Y+ P++AL
Sbjct: 57 QREALDAIREGMNILITTPTASGKTLAFNLPIMETLT-------LNPDATALYIYPVKAL 109
Query: 100 NNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRTSDTSSYEKSKMLKMPPHILITTPES 159
+ D L + EL EL ++ + DT E+ ++ +++T P
Sbjct: 110 SRD-------QLGVLEELESELGLKL---NPSTYDGDTPR-ERRPWIRENSRVILTNPHQ 158
Query: 160 LAIALN-APRFREKLRDVKWVIVDEVHALAENKRGSHLALTLERLREL-----TKRDFVR 213
L L ++R ++++V++DE H GS++AL L RLR + ++ FV
Sbjct: 159 LHRILPWHHQWRRFYSNLRYVVIDEAHQY-RGVFGSNVALLLRRLRRICRYYGSEPQFVL 217
Query: 214 IGLSATIHPLEEVAKFVFGF-----SDDGKPR--PGLIVDVSFAKK----TKITVESVVE 262
SAT+ E ++ + G SDD P I+ + K+ + +++
Sbjct: 218 A--SATLANPAEFSRKLTGLDFRVISDDTSPSGPKHFILYNPYRKRGDPSAHLETSAILS 275
Query: 263 DLVYTPANVLNEALYRRIGELVRSRKTTLIFTNTRSGAERVAYHLKKMFPEWEDKIEAHH 322
LV L + R++ ELV TR E++ +K+ D++ ++
Sbjct: 276 YLVLRGVQTLCFTISRKMAELV-----------TRWTREQLDRENRKLV----DRVTSYR 320
Query: 323 SSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILIGSPKSVNRALQRIGRA 382
+ E R +E LK G L + ++ +LELGIDIG++D VI+ G P ++ Q+ GRA
Sbjct: 321 AGYLAEQRRRIEADLKEGRLLGVTATNALELGIDIGSLDAVIISGYPGTMISTWQQAGRA 380
Query: 383 GHRLHE 388
G L +
Sbjct: 381 GRNLKD 386
>gi|11500032 SKI2-family helicase [Archaeoglobus fulgidus]
Length = 691
Score = 99.1 bits (243), Expect = 2e-19
Identities = 107/414 (25%), Positives = 182/414 (43%), Gaps = 93/414 (22%)
Query: 38 PPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAIISELISLGRRGKLEDKIYCVYVSPLR 97
PPQ A+ ++ G+N+L++ PT +GKTL A +A++ E I G+ +YV PLR
Sbjct: 28 PPQAEAVEKVFSGKNLLLAMPTAAGKTLLAEMAMVREAIKGGK---------SLYVVPLR 78
Query: 98 ALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRTSDTSSYEKSKMLKMPPHILITTP 157
AL + + ++ E +R+ + T D YE I++TT
Sbjct: 79 ALAGEKYESFKK-------------WEKIGLRIGISTGD---YESRDEHLGDCDIIVTTS 122
Query: 158 ESLAIALNAPRFREKLRDVKWVIVDEVHALAENKRGSHLALTLERLRELTKRDFVRIGLS 217
E A +L R ++ V ++VDE+H L KRG+ L + + ++R + K V IGLS
Sbjct: 123 EK-ADSLIRNR-ASWIKAVSCLVVDEIHLLDSEKRGATLEILVTKMRRMNKALRV-IGLS 179
Query: 218 ATIHPLEEVAKFVFG--FSDDGKPRPGL----------IVDVSFAKKTKITVESVVEDLV 265
AT + E+A+++ + D +P P + + D +F+ ++ E +VE+ V
Sbjct: 180 ATAPNVTEIAEWLDADYYVSDWRPVPLVEGVLCEGTLELFDGAFSTSRRVKFEELVEECV 239
Query: 266 YTPANVLNEALYRRIGELVRSRKTTLIFTNTRSGAERVAYHL--------------KKMF 311
V L+F +TR GAE+ A L K +
Sbjct: 240 AENGGV-------------------LVFESTRRGAEKTAVKLSAITAKYVENEGLEKAIL 280
Query: 312 PEWEDKIEA------------HHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGT 359
E E ++ HH+ L R VE+ +RG +K++V++ +L G+++
Sbjct: 281 EENEGEMSRKLAECVRKGAAFHHAGLLNGQRRVVEDAFRRGNIKVVVATPTLAAGVNLPA 340
Query: 360 IDLVI-----LIGSPK--SVNRALQRIGRAGH-RLHEVSEGVILALDRDDLVEV 405
+++ G K V+ Q GRAG + E E +I+ RD + V
Sbjct: 341 RRVIVRSLYRFDGYSKRIKVSEYKQMAGRAGRPGMDERGEAIIIVGKRDREIAV 394
>pir||B70564 hypothetical protein Rv3649 - Mycobacterium tuberculosis (strain
H37RV) >gi|2105045|emb|CAB08839.1| (Z95436) hypothetical
protein Rv3649 [Mycobacterium tuberculosis]
Length = 771
Score = 96.0 bits (235), Expect = 2e-18
Identities = 107/412 (25%), Positives = 186/412 (44%), Gaps = 53/412 (12%)
Query: 48 HKGENVLISSPTGSGKTLSAFLAIISELISLGRRGKLEDKIYCVYVSPLRALNNDIRRNL 107
+ G +V+I + SGK+L+ L +++ L + + + +Y+SP +AL +D R
Sbjct: 71 YAGRHVVIGTGPASGKSLAYQLLVLNALAT-------DSRARALYLSPTKALGHDQLR-- 121
Query: 108 EEPLQEIRELSQELNEEIPEIRVAVRTS--DTSSYEKSKMLKMPPHILITTPES--LAIA 163
+ L +P + T+ S E + + L + PE L++
Sbjct: 122 ---------AAHALAAAVPRLADVAPTAYDGDSPDEVRRFARERSRWLFSNPEMTHLSVL 172
Query: 164 LNAPRFREKLRDVKWVIVDEVHALAENKRGSHLALTLERLRELTKR----DFVRIGLSAT 219
N R+ LR++++VIVDE H GS++A+ L RL L R V + T
Sbjct: 173 RNHARWAVLLRNLRFVIVDECHYY-RGVFGSNVAMVLRRLLRLCARYSAHPTVIFASATT 231
Query: 220 IHP----LEEVAKFVFGFSDDGKPRPGLIVDVSFAKKTKITVESVVEDLVYTPANVLNEA 275
P + + + V ++DG PR V + + + + + E + EA
Sbjct: 232 ASPGATAADLIGQPVVEVTEDGSPRGARTVALW---EPALRSDVIGEHGAPVRRSAGAEA 288
Query: 276 LYRRIGELVRSRKTTLIFTNTRSGAERVAY----HLKKMFPEWEDKIEAHHSSLSREVRL 331
R + +L+ TL F +R AE A L + PE D + ++ + E R
Sbjct: 289 A-RVMADLIVEGAQTLTFVRSRRAAELTALGARARLVDIAPELSDTVASYRAGYLAEDRS 347
Query: 332 EVEERLKRGELKIIVSSTSLELGIDIGTIDLVILIGSPKSVNRALQRIGRAGHRLHEVSE 391
+ + L G+L+ + ++ +LELG+DI +D V+L G P +V Q+ GR+G R +
Sbjct: 348 ALHQALAEGQLRGLATTNALELGVDIAGLDAVVLAGFPGTVASFWQQAGRSGRR----GQ 403
Query: 392 GVILAL-DRDDLVEVTVLAHNAR--KRKLDRIKI-PKNPLDVLVQHLLGMAL 439
G ++ L RDD ++ ++ H A + ++R+ I P NP HLLG L
Sbjct: 404 GALVVLIARDDPLDTYLVHHPAALLDKPVERVVIDPVNP------HLLGPQL 449
>gi|9755332 C4 zinc finger DNA-binding protein of low sequence specificity in
vitro; Probable 119 kD DNA/RNA helicase family member;
Hfm1p [Saccharomyces cerevisiae]
Length = 1187
Score = 94.0 bits (230), Expect = 6e-18
Identities = 124/465 (26%), Positives = 202/465 (42%), Gaps = 74/465 (15%)
Query: 32 KFKSFTPPQRYAIVEIHKG-ENVLISSPTGSGKTLSAFLAIISELISLGRRGKLEDKIYC 90
KF F Q A I++ EN +ISSPTGSGKT+ LAI+ LI KI
Sbjct: 135 KFTEFNKMQSEAFPSIYESNENCIISSPTGSGKTVLFELAIL-RLIKETNSDTNNTKI-- 191
Query: 91 VYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRTSDTSSYEKSKMLKMPP 150
+Y++P ++L ++ +N + V + TSDTS E K K
Sbjct: 192 IYIAPTKSLCYEMYKN--------------WFPSFVNLSVGMLTSDTSFLETEKAKKC-- 235
Query: 151 HILITTPESLAIALNAPRFREKLRD-VKWVIVDEVHALAENKRGSHLALTLERLRELTKR 209
+I+ITTPE + +L + VK V+VDE+H + E KRG+ L + L R+ + +
Sbjct: 236 NIIITTPEKWDLLTRRWSDYSRLFELVKLVLVDEIHTIKE-KRGASLEVILTRMNTMC-Q 293
Query: 210 DFVRIGLSATIHPLEEVAKFVFGFSDDGKPRPGLIVDVSFAKKTKITVESVVEDLVYTPA 269
+ + LSAT+ +E++A ++ +++ P L D S+ ++ + V +
Sbjct: 294 NIRFVALSATVPNIEDLALWL--KTNNELPANILSFDESY---RQVQLTKFVYGYSFNCK 348
Query: 270 N-VLNEALYR----RIGELVRSRKTTLIFTNTRSGAERVAYHL----------KKMFPEW 314
N +A+Y I E + LIF TR+ A L K+
Sbjct: 349 NDFQKDAIYNSKLIEIIEKHADNRPVLIFCPTRASTISTAKFLLNNHIFSKSKKRCNHNP 408
Query: 315 EDK---------IEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVIL 365
DK I HH+ +S E R VE+ G + I+ S+++L +G+++ +++
Sbjct: 409 SDKILNECMQQGIAFHHAGISLEDRTAVEKEFLAGSINILCSTSTLAVGVNLPA--YLVI 466
Query: 366 IGSPKSVNRA----------LQRIGRAGHRLHEVSEGVILALDRDDLVEVTVLAHNARKR 415
I KS N + LQ IGRAG E ++ D L H
Sbjct: 467 IKGTKSWNSSEIQEYSDLDVLQMIGRAGRPQFETHGCAVIMTDSKMKQTYENLIHGT--- 523
Query: 416 KLDRIKIPKNPLDV-LVQHLLG-MALERVWEVEEAYKVVRRAYPY 458
+ ++ L + L++HL +LE V+ +E A +R + Y
Sbjct: 524 -----DVLESSLHLNLIEHLAAETSLETVYSIETAVNWLRNTFFY 563
>gb|AAD30595.1|AC007369_5 (AC007369) Putative RNA helicase [Arabidopsis thaliana]
Length = 2171
Score = 92.1 bits (225), Expect = 2e-17
Identities = 111/445 (24%), Positives = 198/445 (43%), Gaps = 76/445 (17%)
Query: 5 IKWANREYS-DEEIYSILDPIVREWFKRKFKSFTPPQRYAI----VEIHKGENVLISSPT 59
+ W +++ +E++ I + + +W + FK R + K EN+L+ +PT
Sbjct: 472 VPWVSKKVDRNEKLVKITE--MPDWAQPAFKGMQQLNRVQSKVYDTALFKAENILLCAPT 529
Query: 60 GSGKTLSAFLAIISEL-ISLGRRGKLEDKIY-CVYVSPLRALNNDIRRNLEEPLQEIREL 117
G+GKT A L I+ +L ++ G Y VYV+P++AL ++ NL L++ +
Sbjct: 530 GAGKTNVAMLTILQQLEMNRNTDGTYNHGDYKIVYVAPMKALVAEVVGNLSNRLKDYGVI 589
Query: 118 SQELNEEIPEIRVAVRTSDTSSYEKSKMLKMPPHILITTPESLAIALNAPRFREKLRDVK 177
+EL+ + ++ E+++ I++TTPE I R + V+
Sbjct: 590 VRELSGD--------QSLTGREIEETQ-------IIVTTPEKWDIITRKSGDRTYTQLVR 634
Query: 178 WVIVDEVHALAENKRG---SHLALTLERLRELTKRDFVRIGLSATIHPLEEVAKFV---- 230
+I+DE+H L +N+ S +A TL ++ E TK + +GLSAT+ E+VA F+
Sbjct: 635 LLIIDEIHLLHDNRGPVLESIVARTLRQI-ETTKENIRLVGLSATLPNYEDVALFLRVDL 693
Query: 231 ----FGFSDDGKPRPGLIVDVSFAKKTKITVESVVEDLVYTPANVLNEALYRRIGELVRS 286
F F +P P + + K + ++ DL Y VL A ++ V S
Sbjct: 694 KKGLFKFDRSYRPVPLHQQYIGISVKKPLQRFQLMNDLCYQ--KVLAGAGKHQVLIFVHS 751
Query: 287 RK----TTLIFTNTRSGAERVAYHLKK------MFPEWEDKIE-------------AHHS 323
RK T +T + ++ LK+ + ED ++ HH+
Sbjct: 752 RKETSKTARAIRDTAMANDTLSRFLKEDSVTRDVLHSHEDIVKNSDLKDILPYGFAIHHA 811
Query: 324 SLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVI-------------LIGSPK 370
LSR R VE +G ++++VS+ +L G+++ ++I + SP
Sbjct: 812 GLSRGDREIVETLFSQGHVQVLVSTATLAWGVNLPAHTVIIKGTQVYNPEKGAWMELSPL 871
Query: 371 SVNRALQRIGRAGHRLHEVSEGVIL 395
V + L R GR + H EG+I+
Sbjct: 872 DVMQMLGRAGRPQYDQH--GEGIII 894
>pir||T00936 ATP-dependent RNA helicase homolog T24P15.18 - Arabidopsis thaliana
>gi|2673917|gb|AAB88651.1| (AC002561) putative U5 small
nuclear ribonucleoprotein-specific protein [Arabidopsis
thaliana]
Length = 2172
Score = 90.9 bits (222), Expect = 5e-17
Identities = 105/443 (23%), Positives = 193/443 (42%), Gaps = 72/443 (16%)
Query: 5 IKWANREY-SDEEIYSILDPIVREWFKRKFKSFTPPQRYAI----VEIHKGENVLISSPT 59
+ W ++++ S+E++ I D + EW + F+ R + K +N+L+ +PT
Sbjct: 473 VPWVSKKFDSNEKLVKISD--LPEWAQPAFRGMQQLNRVQSKVYGTALFKADNILLCAPT 530
Query: 60 GSGKTLSAFLAIISEL-ISLGRRGKLEDKIY-CVYVSPLRALNNDIRRNLEEPLQEIREL 117
G+GKT A L I+ +L +++ G Y VYV+P++AL + E+
Sbjct: 531 GAGKTNVAVLTILHQLGLNMNPGGTFNHGNYKIVYVAPMKAL--------------VAEV 576
Query: 118 SQELNEEIPEIRVAVRTSDTSSYEKSKMLKMPPHILITTPESLAIALNAPRFREKLRDVK 177
L++ + + V V+ + +K I++TTPE I R + V+
Sbjct: 577 VDSLSQRLKDFGVTVKELSGDQSLTGQEIK-ETQIIVTTPEKWDIITRKSGDRTYTQLVR 635
Query: 178 WVIVDEVHALAENK---RGSHLALTLERLRELTKRDFVRIGLSATIHPLEEVAKF----- 229
+I+DE+H L +N+ S +A TL ++ E TK +GLSAT+ ++VA F
Sbjct: 636 LLIIDEIHLLDDNRGPVLESIVARTLRQI-ESTKEHIRLVGLSATLPNCDDVASFLRVDL 694
Query: 230 ---VFGFSDDGKPRP-----------------GLIVDVSFAKKTKITVESVVEDLVYTPA 269
+F F +P P L+ D+ + K + + V V++
Sbjct: 695 KNGLFIFDRSYRPVPLGQQYIGINVKKPLRRFQLMNDICYQKVVAVAGKHQVLIFVHSRK 754
Query: 270 NVLNEALYRRIGELVRSRKTTLIFTNTRSGAERVAYHLKKMFPEWEDK------IEAHHS 323
A R I + + T F S + + L + + K HH+
Sbjct: 755 ETAKTA--RAIRDTAMANDTLSRFLKEDSQSREILKCLAGLLKNNDLKELLPYGFAIHHA 812
Query: 324 SLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVI---LIGSPK-------SVN 373
L+R R VE + + G L++++S+ +L G+++ ++I + +P+ S
Sbjct: 813 GLTRTDREIVENQFRWGNLQVLISTATLAWGVNLPAHTVIIKGTQVYNPERGEWMELSPL 872
Query: 374 RALQRIGRAGH-RLHEVSEGVIL 395
+Q IGRAG + + EG+I+
Sbjct: 873 DVMQMIGRAGRPQYDQQGEGIII 895
>pir||S61610 HFM1 protein - yeast (Saccharomyces cerevisiae)
>gi|1150588|emb|CAA64136.1| (X94357) ORF NRE1041;
EMBL:SC22156;U22156 [Saccharomyces cerevisiae]
>gi|1322927|emb|CAA96971.1| (Z72773) ORF YGL251c
[Saccharomyces cerevisiae]
Length = 1046
Score = 89.3 bits (218), Expect = 2e-16
Identities = 118/445 (26%), Positives = 194/445 (43%), Gaps = 73/445 (16%)
Query: 51 ENVLISSPTGSGKTLSAFLAIISELISLGRRGKLEDKIYCVYVSPLRALNNDIRRNLEEP 110
EN +ISSPTGSGKT+ LAI+ LI KI +Y++P ++L ++ +N
Sbjct: 14 ENCIISSPTGSGKTVLFELAIL-RLIKETNSDTNNTKI--IYIAPTKSLCYEMYKN---- 66
Query: 111 LQEIRELSQELNEEIPEIRVAVRTSDTSSYEKSKMLKMPPHILITTPESLAIALNAPRFR 170
+ V + TSDTS E K K +I+ITTPE +
Sbjct: 67 ----------WFPSFVNLSVGMLTSDTSFLETEKAKKC--NIIITTPEKWDLLTRRWSDY 114
Query: 171 EKLRD-VKWVIVDEVHALAENKRGSHLALTLERLRELTKRDFVRIGLSATIHPLEEVAKF 229
+L + VK V+VDE+H + E KRG+ L + L R+ + ++ + LSAT+ +E++A +
Sbjct: 115 SRLFELVKLVLVDEIHTIKE-KRGASLEVILTRMNTMC-QNIRFVALSATVPNIEDLALW 172
Query: 230 VFGFSDDGKPRPGLIVDVSFAKKTKITVESVVEDLVYTPAN-VLNEALYR----RIGELV 284
+ +++ P L D S+ ++ + V + N +A+Y I E
Sbjct: 173 L--KTNNELPANILSFDESY---RQVQLTKFVYGYSFNCKNDFQKDAIYNSKLIEIIEKH 227
Query: 285 RSRKTTLIFTNTRSGAERVAYHL----------KKMFPEWEDK---------IEAHHSSL 325
+ LIF TR+ A L K+ DK I HH+ +
Sbjct: 228 ADNRPVLIFCPTRASTISTAKFLLNNHIFSKSKKRCNHNPSDKILNECMQQGIAFHHAGI 287
Query: 326 SREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILIGSPKSVNRA---------- 375
S E R VE+ G + I+ S+++L +G+++ +++I KS N +
Sbjct: 288 SLEDRTAVEKEFLAGSINILCSTSTLAVGVNLPA--YLVIIKGTKSWNSSEIQEYSDLDV 345
Query: 376 LQRIGRAGHRLHEVSEGVILALDRDDLVEVTVLAHNARKRKLDRIKIPKNPLDV-LVQHL 434
LQ IGRAG E ++ D L H + ++ L + L++HL
Sbjct: 346 LQMIGRAGRPQFETHGCAVIMTDSKMKQTYENLIHGT--------DVLESSLHLNLIEHL 397
Query: 435 LG-MALERVWEVEEAYKVVRRAYPY 458
+LE V+ +E A +R + Y
Sbjct: 398 AAETSLETVYSIETAVNWLRNTFFY 422
>pir||H70414 conserved hypothetical protein aq_1328 - Aquifex aeolicus
>gi|2983748|gb|AAC07309.1| (AE000734) hypothetical
protein [Aquifex aeolicus]
Length = 764
Score = 87.8 bits (214), Expect = 5e-16
Identities = 139/581 (23%), Positives = 257/581 (43%), Gaps = 122/581 (20%)
Query: 14 DEEI-YSILDPIVREWFKRKFKSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAII 72
DE I Y +L+PI ++K ++G N L+S+PT +GK+L+AFL +
Sbjct: 42 DERIPYELLNPIQTLFYKE----------------YEGGNALVSAPTSAGKSLTAFLFL- 84
Query: 73 SELISLGRRGKLEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAV 132
RGK K V+ +P R+L + E E+REL ++ +V V
Sbjct: 85 --------RGKEGIK---VFTAPTRSL-------VYEKASELRELFRK--------KVEV 118
Query: 133 RTSDTSSYEKSKMLKMPPHILITTPESLAIALNAPRFREKLRDVKWVIVDEVHALAENKR 192
RT + +E K +K +++ T ESLA+AL + + + V++DE+H L
Sbjct: 119 RTGEV--FELYKEIKS--EVVVATYESLALALR--NRASWIEEARGVVIDEIHQLM---- 168
Query: 193 GSHLALTLERLRELTKRDFVRIGLSATIHPLEEVAKFVFG---FSDDGKPRP---GLIVD 246
GS + E + L ++ +GLSAT+ E++AK++ +P P +I
Sbjct: 169 GSRGWILEEIITFLLDGNYEILGLSATLPGAEQLAKWIKAELFIESRWRPVPLERKIIPL 228
Query: 247 VSFAKKTKITVESVVEDLVYTPANVLNEALYRRIGELVRSRKTTLIFTNTRS-------- 298
+ F + TK+ + ++ + AN L ALY L + + ++F + +S
Sbjct: 229 IKFEEFTKLPKGATQDEKI---ANKLLGALYT----LKKPDEQVILFVHKKSVGWNVLEI 281
Query: 299 -GAERVAYHLKKMFPEWEDKIEA----HHSSLSREVRLEVEERLKRGELKIIVSSTSLEL 353
E++ + E E++ E H++ + +E R E+E+ + G+L ++V++++L
Sbjct: 282 ANREKIGIMNETTPFEKEEREEVELAFHNADVPKEERDEIEKAFREGKLPVLVATSTLAY 341
Query: 354 GIDIGTIDLVILIGSPKSVNR-----------ALQRIGRAGH-RLHEVSEGVILALDRDD 401
G+++ ++I + S R LQ GRAG + E IL +
Sbjct: 342 GVNLPADTVIISVRSFYDRERRQRKFFPDVLDILQMEGRAGRLGIKEKGYSYILPYGAKE 401
Query: 402 LVEVTVLAHNAR---KRKLDRIKIPKNPLDVLVQHLLGMALERVWEVEEAYKVVRRAYPY 458
L+ + K L + + + L VL +L + ++E E K + R Y
Sbjct: 402 ENLAKALSEKLKEEFKPYLREVFLSEEKLKVLSLFIL---VGFLYEGENFRKFLERTYSL 458
Query: 459 HDLPFEDFINVLKYLAGEFSGLEERKVYAKIWLENGKFGKRGKMT-RAIYYMNTGTIPDE 517
+L + I+ +VY WL++ + ++GK++ +A++ + +G P
Sbjct: 459 KELAYSPQID---------------EVYE--WLKDKGYIEKGKLSDKALFCVRSGMPP-- 499
Query: 518 AKIDVFTMDKKYIGTVEEEFAERLIPGDIFVLAGRTYEFVK 558
+ F + +KY+G E + L+ F Y+FVK
Sbjct: 500 INYEEF-LRRKYLGLEEIVYIRPLLFTKKF---DGLYDFVK 536
>pir||T39188 probable U5 snRNP-specific 200kd protein - fission yeast
(Schizosaccharomyces pombe) >gi|6014422|emb|CAB57421.1|
(AL121764) putative U5 snRNP-specific 200kd protein
[Schizosaccharomyces pombe]
Length = 2176
Score = 87.0 bits (212), Expect = 8e-16
Identities = 102/400 (25%), Positives = 169/400 (41%), Gaps = 81/400 (20%)
Query: 51 ENVLISSPTGSGKTLSAFLAIISELISLGRRGKLEDKIY------CVYVSPLRALNNDIR 104
EN+L+ +PTG+GKT A L I++EL ++ ED + VY++PL+AL ++
Sbjct: 536 ENILLCAPTGAGKTNVAMLCILNEL----QKHLREDLSFNLQNFKIVYIAPLKALVQEMV 591
Query: 105 RNLEEPLQEIRELSQELNEEIPEIRVAVRTSDTSSYEKSKMLKMPPHILITTPESLAIAL 164
N + L IRVA T D+ + +K I++TTPE I
Sbjct: 592 NNFSKRLTPY------------NIRVAELTGDS---QLTKQQISETQIIVTTPEKWDIIT 636
Query: 165 NAPRFREKLRDVKWVIVDEVHALAENKRGSHLALTLERL---RELTKRDFVRIGLSATIH 221
+ V+ VI+DEVH L ++RG L + R+ +E T +GLSAT+
Sbjct: 637 RKANDLSYVNLVRLVIIDEVH-LLHDERGPVLESIVARIFRHQEETLEQVRLVGLSATLP 695
Query: 222 PLEEVAKFVFGFSDDGKPRPGLIVDVSFAKKTKITVE--SVVEDLVYTPANVLNEALYRR 279
+VA F+ P+ GL S + + E + E + NEA Y +
Sbjct: 696 NYTDVASFL-----HVDPKKGLFYFDSTYRPCPLKQEFIGITEKTPFKRMQTTNEACYEK 750
Query: 280 IGELVRSRKTTLIFTNTRSGAERVAYHLKKMFPEWED---------------KIEA---- 320
+ + + LIF ++R + A ++ E E + EA
Sbjct: 751 VMQHA-GKNQVLIFVHSRKETAKTARFIRDKALEEETIGHLLRSDAASREILRAEADSTS 809
Query: 321 --------------HHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVI-- 364
HH+ + RE R E+ G ++++VS+ +L G+++ ++I
Sbjct: 810 DENLKDLLPYGFAIHHAGMRREDRQTSEDLFADGTIQVLVSTATLAWGVNLPAHTVIIKG 869
Query: 365 -LIGSPK-------SVNRALQRIGRAGH-RLHEVSEGVIL 395
+ SP+ S LQ +GRAG + EG+I+
Sbjct: 870 TQVYSPEKGIWTELSPQDVLQMLGRAGRPQFDTYGEGIII 909
>sp|P51979|HFM1_YEAST HFM1 PROTEIN >gi|780546|gb|AAA93159.1| (U22156) Hfm1p
[Saccharomyces cerevisiae]
Length = 1048
Score = 86.6 bits (211), Expect = 1e-15
Identities = 117/438 (26%), Positives = 191/438 (42%), Gaps = 73/438 (16%)
Query: 51 ENVLISSPTGSGKTLSAFLAIISELISLGRRGKLEDKIYCVYVSPLRALNNDIRRNLEEP 110
EN +ISSPTGSGKT+ LAI+ LI KI +Y++P ++L ++ +N
Sbjct: 14 ENCIISSPTGSGKTVLFELAIL-RLIKETNSDTNNTKI--IYIAPTKSLCYEMYKN---- 66
Query: 111 LQEIRELSQELNEEIPEIRVAVRTSDTSSYEKSKMLKMPPHILITTPESLAIALNAPRFR 170
+ V + TSDTS E K K +I+ITTPE +
Sbjct: 67 ----------WFPSFVNLSVGMLTSDTSFLETEKAKKC--NIIITTPEKWDLLTRRWSDY 114
Query: 171 EKLRD-VKWVIVDEVHALAENKRGSHLALTLERLRELTKRDFVRIGLSATIHPLEEVAKF 229
+L + VK V+VDE+H + E KRG+ L + L R+ + ++ + LSAT+ +E++A +
Sbjct: 115 SRLFELVKLVLVDEIHTIKE-KRGASLEVILTRMNTMC-QNIRFVALSATVPNIEDLALW 172
Query: 230 VFGFSDDGKPRPGLIVDVSFAKKTKITVESVVEDLVYTPAN-VLNEALYR----RIGELV 284
+ +++ P L D S+ ++ + V + N +A+Y I E
Sbjct: 173 L--KTNNELPANILSFDESY---RQVQLTKFVYGYSFNCKNDFQKDAIYNSKLIEIIEKH 227
Query: 285 RSRKTTLIFTNTRSGAERVAYHL----------KKMFPEWEDK---------IEAHHSSL 325
+ LIF TR+ A L K+ DK I HH+ +
Sbjct: 228 ADNRPVLIFCPTRASTISTAKFLLNNHIFSKSKKRCNHNPSDKILNECMQQGIAFHHAGI 287
Query: 326 SREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILIGSPKSVNRA---------- 375
S E R VE+ G + I+ S+++L +G+++ +++I KS N +
Sbjct: 288 SLEDRTAVEKEFLAGSINILCSTSTLAVGVNLPA--YLVIIKGTKSWNSSEIQEYSDLDV 345
Query: 376 LQRIGRAGHRLHEVSEGVILALDRDDLVEVTVLAHNARKRKLDRIKIPKNPLDV-LVQHL 434
LQ IGRAG E ++ D L H + ++ L + L++HL
Sbjct: 346 LQMIGRAGRPQFETHGCAVIMTDSKMKQTYENLIHGT--------DVLESSLHLNLIEHL 397
Query: 435 LG-MALERVWEVEEAYKV 451
+LE V+ +E A V
Sbjct: 398 AAETSLETVYSIETAAAV 415
>dbj|BAB10376.1| (AB006696) RNA helicase [Arabidopsis thaliana]
Length = 2157
Score = 85.0 bits (207), Expect = 3e-15
Identities = 91/396 (22%), Positives = 168/396 (41%), Gaps = 67/396 (16%)
Query: 48 HKGENVLISSPTGSGKTLSAFLAIISELISLGRRGKL-EDKIYCVYVSPLRALNNDIRRN 106
H EN+L+ +PTG+GKT A ++++ E+ R G L +++ VYV+P++AL ++
Sbjct: 521 HTNENILVCAPTGAGKTNIAMISVLHEIKQHFRDGYLHKNEFKIVYVAPMKALAAEVTSA 580
Query: 107 LEEPLQEIRELSQELNEEIPEIRVAVRTSDTSSYEKSKMLKMPPHILITTPESLAIALNA 166
L + + +EL T + +K +++TTPE +
Sbjct: 581 FSRRLAPLNMVVKEL---------------TGDMQLTKTELEETQMIVTTPEKWDVITRK 625
Query: 167 PRFREKLRDVKWVIVDEVHALAENKRGSHLALTLERLREL-TKRDFVRI-GLSATIHPLE 224
VK +I+DEVH L +++ AL LR++ + + +RI GLSAT+
Sbjct: 626 SSDMSMSMLVKLLIIDEVHLLNDDRGAVIEALVARTLRQVESTQTMIRIVGLSATLPSYL 685
Query: 225 EVAKFVFGFSDDGKPRPGLIVDVSFAKKTKITVESVVEDLVYTPAN-VLNEALYRRIGEL 283
+VA+F+ +D G D S+ + + + N +LNE Y+++ +
Sbjct: 686 QVAQFLRVNTDTGL----FYFDSSYRPVPLAQQYIGITEHNFAARNELLNEICYKKVVDS 741
Query: 284 VRSRKTTLIFTNTRSGAERVAYHLKKMFPEWE--------------------------DK 317
++ +IF ++R + A L + ++E D
Sbjct: 742 IKQGHQAMIFVHSRKDTSKTAEKLVDLARQYETLDLFTNETHPQFQLMKKDVMKSRNKDL 801
Query: 318 IE-------AHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVI------ 364
++ HH+ + R R E G LK++V + +L G+++ +VI
Sbjct: 802 VKFFEAGFGIHHAGMLRSDRTLTERLFSDGLLKVLVCTATLAWGVNLPAHTVVIKGTQLY 861
Query: 365 --LIGSPKSVNR--ALQRIGRAGH-RLHEVSEGVIL 395
G K + +Q GRAG + + EG+I+
Sbjct: 862 DAKAGGWKDLGMLDVMQIFGRAGRPQFDKSGEGIII 897
>gi|6321856 RRP3 is a DEAD box gene homologous to eIF-4a which encodes an
RNA-dependent ATPase possessing helicase activity which
is not specific for RNA; Rrp3p [Saccharomyces
cerevisiae] >gi|731667|sp|P38712|RRP3_YEAST
ATP-DEPENDENT RRNA HELICASE RRP3 >gi|626623|pir||S46713
ATP-dependent RNA helicase YHR065c [similarity] - yeast
(Saccharomyces cerevisiae) >gi|487961|gb|AAB68392.1|
(U00061) Yhr065cp [Saccharomyces cerevisiae]
Length = 543
Score = 84.7 bits (206), Expect = 4e-15
Identities = 96/395 (24%), Positives = 168/395 (42%), Gaps = 53/395 (13%)
Query: 37 TPPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAIISELISLGRRGKLEDKIYCVYVSPL 96
TP Q AI +G +++ + TGSGKT + + I++ L ++ Y ++P
Sbjct: 147 TPIQSKAIPPALEGHDIIGLAQTGSGKTAAFAIPILNRL------WHDQEPYYACILAPT 200
Query: 97 RALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRTSDTSSYEKSKMLKMPPHILITT 156
R L Q+I+E L + +R + ++++ L PHI+I T
Sbjct: 201 REL-----------AQQIKETFDSLGS-LMGVRSTCIVGGMNMMDQARDLMRKPHIIIAT 248
Query: 157 PESLAIAL-NAPRFREKLRDVKWVIVDEVHALAENKRGSHLALTLERLRELTKRDFVRIG 215
P L L N F LR +K++++DE L + + G L L+
Sbjct: 249 PGRLMDHLENTKGF--SLRKLKFLVMDEADRLLDMEFGPVLDRILK-------------- 292
Query: 216 LSATIHPLEEVAKFVFGFSDDGK----PRPGLIVDVSFAKKTKI-TVESVVEDLVYTPAN 270
I P +E ++F + K R L V A K TV+++V+ L+ P
Sbjct: 293 ----IIPTQERTTYLFSATMTSKIDKLQRASLTNPVKCAVSNKYQTVDTLVQTLMVVPGG 348
Query: 271 VLNEALYRRIGELVRSRKTTLIFTNTRSGAERVAYHLKKMFPEWEDKIEAHHSSLSREVR 330
+ N L + E + KT +IFT T++ AER++ + E A H L++ R
Sbjct: 349 LKNTYLIYLLNEFIG--KTMIIFTRTKANAERLSGLCNLL----EFSATALHGDLNQNQR 402
Query: 331 LEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILIGSPKSVNRALQRIGRAGHRLHEVS 390
+ + K G+ I+V++ G+DI ++D+V+ P + R+GR R
Sbjct: 403 MGSLDLFKAGKRSILVATDVAARGLDIPSVDIVVNYDIPVDSKSYIHRVGRTA-RAGRSG 461
Query: 391 EGVILALDRDDLVEVTVLAHNARKRKLDRIKIPKN 425
+ + L D +E+ + +KL + + KN
Sbjct: 462 KSISLVSQYD--LELILRIEEVLGKKLPKESVDKN 494
>gi|6321020 putative ATP-dependent RNA helicase; Brr2p [Saccharomyces
cerevisiae] >gi|731380|sp|P32639|BRR2_YEAST PRE-MRNA
SPLICING HELICASE BRR2 >gi|1077724|pir||S50675 pre-mRNA
splicing helicase BRR2 - yeast (Saccharomyces
cerevisiae) >gi|603413|gb|AAB64699.1| (U18922) Brr2p:
Putative ATP-dependent RNA helicase [Saccharomyces
cerevisiae] >gi|1699380|gb|AAB37500.1|
Rss1p=ATP-dependent RNA helicase homolog [Saccharomyces
cerevisiae, Peptide Mutant, 2163 aa]
Length = 2163
Score = 84.7 bits (206), Expect = 4e-15
Identities = 109/438 (24%), Positives = 184/438 (41%), Gaps = 75/438 (17%)
Query: 11 EYSDEEIYSILDPIVREWFKRKFKSFTPPQRYAIVEIHKGE-NVLISSPTGSGKTLSAFL 69
+Y +EI S+ D + + S P Q +G+ N+LI +PTGSGKT A L
Sbjct: 474 DYELKEITSLPDWCQEAFPSSETTSLNPIQSKVFHAAFEGDSNMLICAPTGSGKTNIALL 533
Query: 70 AIISELIS--LGRRGKLEDKIY-CVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIP 126
++ L + KL + VY++PL+AL +++RE + L
Sbjct: 534 TVLKALSHHYNPKTKKLNLSAFKIVYIAPLKALVQ----------EQVREFQRRL--AFL 581
Query: 127 EIRVAVRTSDTSSYEKSKMLKMPPHILITTPESLAIALNAPRFREKLRDVKWVIVDEVHA 186
I+VA T D+ S+ +L++TPE I + V+ +I+DE+H
Sbjct: 582 GIKVAELTGDS---RLSRKQIDETQVLVSTPEKWDITTRNSNNLAIVELVRLLIIDEIHL 638
Query: 187 LAENKRGSHLALTLERLRELTK--RDFVR-IGLSATIHPLEEVAKFVFGFSDDGKPRPGL 243
L ++ RG L + R +K +++ R IGLSAT+ E+V +F+ P+ GL
Sbjct: 639 LHDD-RGPVLESIVARTFWASKYGQEYPRIIGLSATLPNYEDVGRFL------RVPKEGL 691
Query: 244 IVDVSFAKKTKITVE--SVVEDLVYTPANVLNEALYRRIGELVRSRKTTLIFTNTRSGAE 301
S + ++ + + E +N+A Y ++ E + ++F ++R
Sbjct: 692 FYFDSSFRPCPLSQQFCGIKERNSLKKLKAMNDACYEKVLESINEGNQIIVFVHSRKETS 751
Query: 302 RVAYHLKKMFPE---------------------------------WEDKIEAHHSSLSRE 328
R A LK F E E I HH+ L+R
Sbjct: 752 RTATWLKNKFAEENITHKLTKNDAGSKQILKTEAANVLDPSLRKLIESGIGTHHAGLTRS 811
Query: 329 VRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVIL---IGSPK-------SVNRALQR 378
R E+ G L+++V + +L G+++ ++I + SP+ S LQ
Sbjct: 812 DRSLSEDLFADGLLQVLVCTATLAWGVNLPAHTVIIKGTDVYSPEKGSWEQLSPQDVLQM 871
Query: 379 IGRAGH-RLHEVSEGVIL 395
+GRAG R EG+I+
Sbjct: 872 LGRAGRPRYDTFGEGIII 889
>pir||T38420 probable dna helicases - fission yeast (Schizosaccharomyces pombe)
(fragment) >gi|2656007|emb|CAB16187.1| (Z99126)
DEAD/DEAH box helicase [Schizosaccharomyces pombe]
Length = 643
Score = 83.5 bits (203), Expect = 9e-15
Identities = 88/353 (24%), Positives = 161/353 (44%), Gaps = 45/353 (12%)
Query: 40 QRYAIVEIHKGENVLISSPTGSGKTLSAFLAIISELISLGRRGKLEDKIYCVYVSPLRAL 99
Q AI + G +V++S+ T SGK+L + I+ L+ +++ +V P ++L
Sbjct: 316 QADAINHLWNGFHVIVSTSTSSGKSLIYQIPILQSLLE-------DNQSTAFFVFPTKSL 368
Query: 100 NNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRTSDTSSYEKSKMLKMPPHILITTPES 159
D +++L + L + L IRV DT + +++ +I+ T P+
Sbjct: 369 AQDQKKSLIDILSYMPTLKN--------IRVDTFDGDTPLESRESIIRSA-NIIFTNPDM 419
Query: 160 L--AIALNAPRFREKLRDVKWVIVDEVHALAENKRGSHLALTLERLRELTK----RDFVR 213
L I NA R+ +++K ++DE H G H+A L R+R + + +
Sbjct: 420 LHQTILPNANRWYYFFKNLKLFVLDEAHVY-NGIFGVHVAFVLRRMRRIAEYFGNSQYRF 478
Query: 214 IGLSATIH-PLEEVAKFVFGFSDDGKPRPGLIVDVSFAKKTKITVESVVEDLVYTPANVL 272
+ SATI PL+ + K +FG + I +++ + + V+ + Y
Sbjct: 479 VSCSATIEDPLQHMKK-IFGVDN--------IKLINYTSSPSGSKKFVMWNPPYVDPKHP 529
Query: 273 NEALYRRIGE-------LVRSRKTTLIFTNTRSGAER----VAYHLK-KMFPEWEDKIEA 320
++ I E R T++F R E V LK K + KI++
Sbjct: 530 DDGKKSAISEASKLLIKFAEKRVRTIVFCRVRKTCESLMRLVRQELKTKQKGDLLSKIQS 589
Query: 321 HHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILIGSPKSVN 373
+ + + + R ++E + G+L I+++ +LELGIDIG++D VI IG P S++
Sbjct: 590 YRAGYTVQERRKIESEMFNGKLYGIIATNALELGIDIGSLDAVITIGFPYSLS 642
>pir||H64474 hypothetical protein MJ1401 - Methanococcus jannaschii
>gi|1592049|gb|AAB99409.1| (U67580) putative ATP
dependent RNA helicase [Methanococcus jannaschii]
Length = 808
Score = 81.9 bits (199), Expect = 3e-14
Identities = 109/403 (27%), Positives = 183/403 (45%), Gaps = 56/403 (13%)
Query: 4 EIKWANREYSDEEIYSILDPIVREWFKRKFKSFTPPQRYAI-VEIHKGENVLISSPTGSG 62
E K N + + +I L I++ R + P Q ++ + G+++LI S T SG
Sbjct: 183 EDKIENYKIDELDIPEELKEIIKS---RGIEELLPVQTLSVKAGLLNGDDLLIISATSSG 239
Query: 63 KTLSAFLAIISELISLGRRGKLEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQELN 122
KTL LA I LI G++ +++ PL AL N + E +E ++L
Sbjct: 240 KTLIGELAGIKNLIKTGKK--------FLFLVPLVALAN-------QKYLEFKERYEKLG 284
Query: 123 EEIPEIRVAV-RTSDTSSYEKSKMLKMPPHILITTPESLAIALNAPRFREKLRDVKWVIV 181
++ +RV + R E S + I++ T E + + R L+D+ V++
Sbjct: 285 FKV-SLRVGLGRIGKKVDVETS----LDADIIVGTYEGIDYLIRTKR----LKDIGTVVI 335
Query: 182 DEVHALAENKRGSHLALTLERLRELTKRDFVRIGLSATIHPLEEVAKFVFG--FSDDGKP 239
DE+H+L +RG+ L + RLR L K + +I LSATI +E+AK + +G+P
Sbjct: 336 DEIHSLNLEERGARLDGLIGRLRFLFK-EAQKIYLSATIGNPKELAKQLNAKLVLYNGRP 394
Query: 240 RPGLIVDVSFAKKTKITVESVVEDLVYTPANVLNEALYRRIGELVR--SRKTTLIFTNTR 297
P L + F K + N++ E + R + + R LIFT +R
Sbjct: 395 VP-LERHIIFCKND------------FAKLNIIKEIVKREWQNISKFGYRGQCLIFTYSR 441
Query: 298 SGAERVAYHLKKMFPEWEDKIEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDI 357
AE +A LK K E +H + R +VE+ +++ +V++ +L G+D
Sbjct: 442 KRAEYLAKALKSK----GIKAEFYHGGMEYIKRRKVEDDFANQKIQCVVTTAALSAGVDF 497
Query: 358 --GTIDLVILIGSPKSVNRA--LQRIGRAGHR-LHEVSEGVIL 395
T+ L L +N A Q GRAG + +HE+ + +L
Sbjct: 498 PASTVILESLAMGADWLNPAEFQQMCGRAGRKGMHEIGKVYLL 540
>pir||E72775 probable helicase APE0191 - Aeropyrum pernix (strain K1)
>gi|5103582|dbj|BAA79103.1| (AP000058) 702aa long
hypothetical helicase [Aeropyrum pernix]
Length = 702
Score = 81.9 bits (199), Expect = 3e-14
Identities = 107/405 (26%), Positives = 180/405 (44%), Gaps = 87/405 (21%)
Query: 47 IHKGENVLISSPTGSGKTLSAFLAIISELISLGRRGKLEDKIYCVYVSPLRALNNDIRRN 106
+ KGEN+++++PTGSGKT A +AI++ L G R Y+ PL+++ + +
Sbjct: 7 VEKGENLVVAAPTGSGKTFIALVAIVNSLARAGGR--------AFYLVPLKSVAYEKYTS 58
Query: 107 ---LEEPLQEIRELSQELNEEIPEIRVAVRTSDTSSYEK-SKMLKMPPHILITTPESLAI 162
L +++ + E PE V + T YEK +L++ P SLA
Sbjct: 59 FSILSRMGLKLKISVGDFREGPPEAPVVIAT-----YEKFDSLLRVSP--------SLA- 104
Query: 163 ALNAPRFREKLRDVKWVIVDEVHALAENKRGSHLALTLERLRELTKRDFVRIGLSATIHP 222
R+V +IVDE+H++++ KRG L + R+ + + +GLSAT+
Sbjct: 105 -----------RNVSVLIVDEIHSVSDPKRGPILESIVSRML-ASAGEAQLVGLSATVPN 152
Query: 223 LEEVAKFVFGFSDDGKPRPGLIVDVSFAKKTKI------------------------TVE 258
E+A+++ G + RP + + F K+ K+ +E
Sbjct: 153 AGEIAEWIGGKIVESSWRPVPLREYVF-KEYKLYSPTGGLREVPRVYGLYDLDLAAEAIE 211
Query: 259 SVVEDLVYT----PANVLNEALYRRIGELVRSRKTTLIFTNTRSGAE----RVAYHLKKM 310
+ LV+T A L + +R+G + SR+ +++ S AE VA L +
Sbjct: 212 DGGQALVFTYSRRRAVTLAKRAAKRLGRRLSSREAR-VYSAEASRAEGAPRSVAEELASL 270
Query: 311 FPEWEDKIEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVI------ 364
I HH+ L +R VEE + G +K++ S+ +L G+++ +VI
Sbjct: 271 IAA---GIAYHHAGLPPSLRKTVEEAFRAGAVKVVYSTPTLAAGVNLPARRVVIDSYYRY 327
Query: 365 --LIGSPKSVNRALQRIGRAGH-RLHEVSEGVILA--LDR-DDLV 403
P V Q GRAG L E E +I+A LDR +DL+
Sbjct: 328 EAGFREPIRVAEYKQMAGRAGRPGLDEFGEAIIVAERLDRPEDLI 372
>gb|AAG20465.1| (AE005119) DNA repair protein; Rad24b [Halobacterium sp. NRC-1]
Length = 783
Score = 81.1 bits (197), Expect = 5e-14
Identities = 108/410 (26%), Positives = 174/410 (42%), Gaps = 63/410 (15%)
Query: 38 PPQRYAIVE-IHKGENVLISSPTGSGKTLSAFLAIISELISLGRRGKLEDKIYCVYVSPL 96
PPQ A+ + +G N++ S PT SGKTL A LA++S + G +Y+ PL
Sbjct: 27 PPQAEAVERGVTEGANLVASVPTASGKTLIAQLAMLSAIAEGGDSPTFSGDGTALYIVPL 86
Query: 97 RALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRTSDTSSYEKSKMLKMPPHILITT 156
RAL E +QE E ++V S T +YE+ I++ T
Sbjct: 87 RALAG--------------EKAQEF-EAFERFGLSVGVS-TGNYERDGARLADNDIVVAT 130
Query: 157 PESL-AIALNAPRFREKLRDVKWVIVDEVHALAENKRGSHLALTLERLRELTKRDFVRIG 215
E + ++ N + + D+ V+ DEVH + ++ RG L +TL +LR+ D +
Sbjct: 131 SEKVDSLVRNGAGW---IDDLSCVVADEVHLVDDDHRGPTLEVTLAKLRQQV-ADLQVVA 186
Query: 216 LSATIHPLEEVAKFVFGFSDDGKPRP---------GLIVDVSFAKKTKITVES------V 260
LSAT+ E+A ++ D RP G + + +++V S V
Sbjct: 187 LSATVGNAGELAAWLDAELVDSDWRPIELRTGVHYGQSLHYDDGTQAELSVGSGSQTAAV 246
Query: 261 VEDLVYTPANVLNEALYRRIGELVRSRKTTLIFTNTRSGAER-----VAYHLK-----KM 310
V D + + L RR E +R+ + N S AER +A ++ +
Sbjct: 247 VADTLADDGSTLVFVNSRRNAE-ASARRLADVTGNALSSAERERLADIAAEIRGVSDTET 305
Query: 311 FPEWEDKIEA----HHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILI 366
E D + + HH+ L+RE R VEE + +K + ++ +L G++ +V+
Sbjct: 306 SDELADAVASGAAFHHAGLAREHRELVEEAFRDRLVKAVSATPTLAAGVNTPARRVVVRD 365
Query: 367 G----------SPKSVNRALQRIGRAGH-RLHEVSEGVILALDRDDLVEV 405
P V Q GRAG L E V+LA D+L E+
Sbjct: 366 WQRYDGTAGGMQPLDVLEVHQMFGRAGRPGLDPYGEAVLLANSHDELEEL 415
>dbj|BAB14698.1| (AK023840) unnamed protein product [Homo sapiens]
Length = 774
Score = 80.0 bits (194), Expect = 1e-13
Identities = 91/395 (23%), Positives = 168/395 (42%), Gaps = 63/395 (15%)
Query: 47 IHKGENVLISSPTGSGKTLSAFLAIISELIS-LGRRGKLE-DKIYCVYVSPLRALNNDIR 104
+ EN+L+ +PTG+GKT A + ++ E+ + G + D +Y++P+R+L
Sbjct: 168 LETAENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIYIAPMRSL----- 222
Query: 105 RNLEEPLQEIRELSQELNEEIPEIRVAVRTSDTSSYEKSKMLKMPPHILITTPESLAIAL 164
++E+ + + + V T ++ SK I++ TPE I
Sbjct: 223 ---------VQEMVGSFGKRLATYGITVAEL-TGDHQLSKEEISATQIIVCTPEKWDIIT 272
Query: 165 NAPRFREKLRDVKWVIVDEVHALAENKRGSHLALTLERLR--ELTKRDFVRIGLSATIHP 222
R + V+ +I+DE+H L +++ AL +R E+T+ D IGLSAT+
Sbjct: 273 RKGGERTYTQLVRLIILDEIHLLHDDRGPVLEALVARAIRNIEMTQEDVRLIGLSATLPN 332
Query: 223 LEEVAKFV--------FGFSDDGKPRPGLIVDVSFAKKTKITVESVVEDLVYTPANVLNE 274
E+VA F+ F F + +P P V +K I ++ ++VY ++
Sbjct: 333 YEDVATFLRVDPAKGLFYFDNSFRPVPLERTYVGITEKKAIKRFQIMNEIVYE--KIMEH 390
Query: 275 ALYRRIGELVRSRKTTL-----------------IFTNTRSGAERVAYHLKKMFPEWEDK 317
A ++ V SRK T +F S + V + E K
Sbjct: 391 AGKNQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELK 450
Query: 318 ------IEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVI---LIGS 368
HH+ ++R R VE+ ++++VS+ +L G+++ ++I + S
Sbjct: 451 DLLLYGFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYS 510
Query: 369 PK-------SVNRALQRIGRAGHRLHEV-SEGVIL 395
P+ LQ +GRAG ++ EG+++
Sbjct: 511 PEKGRWTELGALDILQMLGRAGRPQYDTKGEGILI 545
>pir||C64440 DNA repair protein RAD24 homolog (intein-containing) -
Methanococcus jannaschii >gi|1499976|gb|AAB99126.1|
(U67555) putative SKI2-family helicase [Methanococcus
jannaschii]
Length = 1195
Score = 80.0 bits (194), Expect = 1e-13
Identities = 94/354 (26%), Positives = 158/354 (44%), Gaps = 74/354 (20%)
Query: 38 PPQRYAIVE--IHKGENVLISSPTGSGKTLSAFLAIISELISLGRRGKLEDKIYCVYVSP 95
PPQ+ A+ + K +N LIS PT SGKTL +A+I+ L+ G + K +++ P
Sbjct: 18 PPQKKALERGLLDKNKNFLISIPTASGKTLIGEMALINHLLD-GNKNPTNKK--GIFIVP 74
Query: 96 LRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRTSDTSSYEKSKMLKMPPHILIT 155
L+AL E +E + + +R+A+ D Y++ + L H++IT
Sbjct: 75 LKAL-------ASEKYEEFKSKYERYG-----LRIALSIGD---YDEDEDLS-KYHLIIT 118
Query: 156 TPESLAIALNAPRFREK---LRDVKWVIVDEVHALAENKRGSHLALTLERLRELTKRDFV 212
T E L +R K + DV V+VDE+H + + RG L + L +L+E +
Sbjct: 119 TAEKL-----DSLWRHKIDWINDVSVVVVDEIHLINDETRGGTLEILLTKLKEFNVQ--- 170
Query: 213 RIGLSATIHPLEEVAKFVFG--FSDDGKPRPGLIVDVSFAKKTKITVESVVEDLVYTPAN 270
IGLSATI +E+A+++ DD +P V++ +E + ++ A
Sbjct: 171 IIGLSATIGNPDELAEWLNAELIVDDWRP-----VELKKGIYKNEAIEFINGEIREIKA- 224
Query: 271 VLNEALYRRIGELVRSRKTTLIFTNTRSGA--ERVAYHLKKMFPEWEDKIEA-------- 320
V N +Y + + V+ L+F NT+ A E +LKK E E+KI
Sbjct: 225 VDNNDIYNLVVDCVKEGGCCLVFCNTKRNAVNEAKKLNLKKFLTE-EEKIRLKEIAEEIL 283
Query: 321 -----------------------HHSSLSREVRLEVEERLKRGELKIIVSSTSL 351
HH+ L+ + R VE+ ++ +K+I + +L
Sbjct: 284 SILEPPTEMCKTLAECILNGSAFHHAGLTYQHRKIVEDAFRKRLIKVICCTPTL 337
>pir||C69187 conserved hypothetical protein MTH656 - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2621738|gb|AAB85161.1| (AE000845) ATP-dependent RNA
helicase related protein [Methanobacterium
thermoautotrophicum]
Length = 837
Score = 80.0 bits (194), Expect = 1e-13
Identities = 109/393 (27%), Positives = 168/393 (42%), Gaps = 62/393 (15%)
Query: 25 VREWFKRKFKS-----FTPPQRYAI-VEIHKGENVLISSPTGSGKTLSAFLAIISELISL 78
V E FKR K P Q A+ + +GE++++ S T SGKTL A LA I +
Sbjct: 207 VPEKFKRMLKREGNTVLRPVQVLAVDAGLLEGEDLMVVSATASGKTLIAELAGIPRALG- 265
Query: 79 GRRGKLEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRTSDTS 138
G + +Y++PL AL N R+ ++ L I +R D
Sbjct: 266 GEK--------FIYLTPLVALANQKYRDFRRRYSPLK-----LKTAIKVGMSRIRARDEL 312
Query: 139 SYEKSKMLKMPPHILITTPESLAIALNAPRFREKLRDVKWVIVDEVHALAENKRGSHLAL 198
++ + K I++ T E + L A R L DV V++DE+H L + +RGS L
Sbjct: 313 RIPETDVSKAD--IVVGTYEGMDYILRAGR-SGILGDVGVVVIDEIHTLEDEERGSRLKG 369
Query: 199 TLERLRELTKRDFVRIGLSATIHPLEEVAKFVFGF---SDDGKPRPGLIVDVSFAKKTKI 255
++R+R L D I LSAT+ EVA FG D +P P
Sbjct: 370 MIKRIRRLFP-DAQIIALSATVKNNLEVAS-EFGLRLVEYDRRPVP-------------- 413
Query: 256 TVESVVEDLVYTPANVLNEALYRRIGELVRS-------RKTTLIFTNTRSGAERVAYHLK 308
+ LV++ + L R+ E S R T++FTN+R +A +L
Sbjct: 414 ----LERHLVFSRGEEDKKNLILRLAEREFSTESEKGFRGQTIVFTNSRRKTRLIADYLT 469
Query: 309 KMFPEWEDKIEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLV---IL 365
+ + A+H+ LS R +E EL IV++ +L G+D +V +L
Sbjct: 470 RR----GVRAAAYHAGLSYRERQRIERAFASQELAAIVTTAALAAGVDFPASQVVFETLL 525
Query: 366 IGSPKSV-NRALQRIGRAGHRLHEVSEGVILAL 397
+G+ + N Q +GRAG + GV+ L
Sbjct: 526 MGNRWLMPNEFAQMLGRAGRPSYH-DRGVVYVL 557
>dbj|BAB14906.1| (AK024391) unnamed protein product [Homo sapiens]
Length = 1811
Score = 78.4 bits (190), Expect = 3e-13
Identities = 91/394 (23%), Positives = 168/394 (42%), Gaps = 69/394 (17%)
Query: 51 ENVLISSPTGSGKTLSAFLAIISELIS-LGRRGKLE-DKIYCVYVSPLRALNNDIRRNLE 108
EN+L+ +PTG+GKT A + ++ E+ + G + D +Y++P+R+L
Sbjct: 172 ENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIYIAPMRSL--------- 222
Query: 109 EPLQEIRELSQELNEEIPEIRVAVRTSDTSSYEKSKMLKMPPHILITTPESLAIALNAPR 168
++E+ + + + V T ++ K I++ TPE I
Sbjct: 223 -----VQEMVGSFGKRLATYGITVAEL-TGDHQLCKEEISATQIIVCTPEKWDIITRKGG 276
Query: 169 FREKLRDVKWVIVDEVHALAENKRGSHLALTLERLR--ELTKRDFVRIGLSATIHPLEEV 226
R + V+ +I+DE+H L +++ AL +R E+T+ D IGLSAT+ E+V
Sbjct: 277 ERTYTQLVRLIILDEIHLLHDDRGPVLEALVARAIRNIEMTQEDVRLIGLSATLPNYEDV 336
Query: 227 AKFV--------FGFSDDGKPRPGLIVDVSFAKKTKITVESVVEDLVYTPANVLNEALYR 278
A F+ F F + +P P V +K I ++ ++VY ++ A
Sbjct: 337 ATFLRVDPAKGLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYE--KIMEHAGKN 394
Query: 279 RIGELVRSRKTTL-----------------IFTNTRSGAERVA---------YHLKKMFP 312
++ V SRK T +F S + V LK + P
Sbjct: 395 QVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLP 454
Query: 313 EWEDKIEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVI---LIGSP 369
HH+ ++R R VE+ ++++VS+ +L G+++ ++I + SP
Sbjct: 455 YG---FAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSP 511
Query: 370 KSVN-------RALQRIGRAGHRLHEV-SEGVIL 395
+ + LQ +GRAG ++ EG+++
Sbjct: 512 EKGHWTELGALDILQMLGRAGRPQYDTKGEGILI 545
>emb|CAC11964.1| (AL445065) DNA helicase related protein [Thermoplasma acidophilum]
Length = 674
Score = 78.4 bits (190), Expect = 3e-13
Identities = 79/341 (23%), Positives = 147/341 (42%), Gaps = 63/341 (18%)
Query: 40 QRYAIVEIHKGENVLISSPTGSGKTLSAFLAIISELISLGRRGKLEDKIYCVYVSPLRAL 99
QR AI +I KG NV++S PT +GKTL A+ AI + + +Y+ PLR+L
Sbjct: 27 QRMAIEQIRKGRNVVVSVPTAAGKTLIAYSAIYE---------TFQRNLKSIYIVPLRSL 77
Query: 100 NNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRTSDTSSYEKSKMLKMPPHILITTPES 159
+++ ELS+ + ++ + V+ S + +K +++T+ ++
Sbjct: 78 ----------AMEKFSELSR-----LRDLGLKVKMSIGDYDDSPDFIKRYDAVILTSEKA 122
Query: 160 LAIALNAPRFREKLRDVKWVIVDEVHALAENKRGSHLALTLERLRELTKRDFVRIGLSAT 219
++ + P L DV +++DE+H + + RG L T+ + D + LSAT
Sbjct: 123 DSLLHHDPYI---LNDVGLLVLDEIHTIGDESRGPTLE-TVASIARYVNPDVRILALSAT 178
Query: 220 IHPLEEVAKFVFG--FSDDGKPRPGLIVDVSFAKKTKITVESVVEDLVYTPANVLNEALY 277
+ E+A ++ D +P P KT I + L ++
Sbjct: 179 VSNAMELASWLDASLIKSDFRPVP---------LKTGILYR---DQLYLDGKRRSGVSIN 226
Query: 278 RRIGELVRSRKTTLIFTNTRSGAERVAYHLKKMFPE-------------WEDKIEA---- 320
+ I E V L+F ++R AE A L ++F ++D +
Sbjct: 227 QIIRETVEDNGQVLMFVSSRKKAEDTARDLAQIFGSDANIKISSDETNVYDDMLNEILPR 286
Query: 321 ----HHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDI 357
HH+ LS + R +E + +K+IV++ +L G+++
Sbjct: 287 GVAFHHAGLSNDQRAFIEREFRARRIKVIVATPTLAAGVNL 327
>dbj|BAB01770.1| (AB022215) DEAD-Box RNA helicase-like protein [Arabidopsis
thaliana]
Length = 616
Score = 78.0 bits (189), Expect = 4e-13
Identities = 83/401 (20%), Positives = 167/401 (40%), Gaps = 34/401 (8%)
Query: 24 IVREWFKRKFKSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAIISELISLGRRGK 83
IV+ + + P Q+ + +G +++ + TG+GKTL+ + II ++I +
Sbjct: 115 IVKALSSKGIEKLFPIQKAVLEPAMEGRDMIGRARTGTGKTLAFGIPIIDKIIKYNAKHG 174
Query: 84 LEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRTSDTSSYEKS 143
C+ ++P R L R++ +E E P + T ++
Sbjct: 175 RGRNPLCLVLAPTREL--------------ARQVEKEFRESAPSLDTICLYGGTPIGQQM 220
Query: 144 KMLKMPPHILITTPESLAIALNAPRFREKLRDVKWVIVDEVHALAENKRGSHLALTLERL 203
+ L + + TP + + R L +V++V++DE + + + + LE+L
Sbjct: 221 RQLDYGVDVAVGTPGRVIDLMK--RGALNLSEVQFVVLDEADQMLQVGFAEDVEIILEKL 278
Query: 204 RELTKRDFVRIGLSATIHPLEEVAKFVFGFSDDGKPRPGLIVDVSFAKKTKITVESVVED 263
E + + + I L + K++ + L+ D IT S++ D
Sbjct: 279 PEKRQSMMFSATMPSWIRSLTK--KYL-----NNPLTVDLVGDSDQKLADGITTYSIIAD 331
Query: 264 LVYTPANVLNEALYRRIGELVRSRKTTLIFTNTRSGAERVAYHLKKMFPEWEDKIEAHHS 323
Y A+++ + E + K ++FT T+ A+R++Y L + F K EA H
Sbjct: 332 S-YGRASIIGPL----VTEHAKGGKC-IVFTQTKRDADRLSYALARSF-----KCEALHG 380
Query: 324 SLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILIGSPKSVNRALQRIGRAG 383
+S+ R + G I+V++ G+D+ +DL+I P + + R GR G
Sbjct: 381 DISQSQRERTLAGFRDGHFNILVATDVAARGLDVPNVDLIIHYELPNNTETFVHRTGRTG 440
Query: 384 HRLHEVSEGVILALDRDDLVEVTVLAHNARKRKLDRIKIPK 424
+ S +I + D+ V++ +R +L I + +
Sbjct: 441 RAGKKGSAILIYSQDQSRAVKIIEREVGSRFTELPSIAVER 481
>emb|CAA94089.1| (Z70200) U5 snRNP-specific 200kD protein [Homo sapiens]
Length = 1701
Score = 77.3 bits (187), Expect = 7e-13
Identities = 90/394 (22%), Positives = 167/394 (41%), Gaps = 69/394 (17%)
Query: 51 ENVLISSPTGSGKTLSAFLAIISELIS-LGRRGKLE-DKIYCVYVSPLRALNNDIRRNLE 108
EN+L+ +PTG+GKT A + ++ E+ + G + D +Y++P+R+L
Sbjct: 62 ENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIYIAPMRSL--------- 112
Query: 109 EPLQEIRELSQELNEEIPEIRVAVRTSDTSSYEKSKMLKMPPHILITTPESLAIALNAPR 168
++E+ + + + V T ++ K I++ TPE I
Sbjct: 113 -----VQEMVGSFGKRLATYGITVAEL-TGDHQLCKEEISATQIIVCTPEKWDIITRKGG 166
Query: 169 FREKLRDVKWVIVDEVHALAENKRGSHLALTLERLR--ELTKRDFVRIGLSATIHPLEEV 226
R + V+ +++DE+H L +++ AL +R E+T+ D IGLSAT+ E+V
Sbjct: 167 ERTYTQLVRLIVLDEIHLLHDDRGPVLEALVARAIRNIEMTQEDVRLIGLSATLPNYEDV 226
Query: 227 AKFV--------FGFSDDGKPRPGLIVDVSFAKKTKITVESVVEDLVYTPANVLNEALYR 278
A F+ F F + +P P V +K I ++ ++VY ++ A
Sbjct: 227 ATFLRVDPAKGLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYE--KIMEHAGKN 284
Query: 279 RIGELVRSRKTTL-----------------IFTNTRSGAERVA---------YHLKKMFP 312
++ V SRK T +F S + V LK + P
Sbjct: 285 QVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLP 344
Query: 313 EWEDKIEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVI---LIGSP 369
HH+ ++R R VE+ ++++VS+ +L G+++ ++I + SP
Sbjct: 345 YG---FAIHHAGMTRVDRTLVEDLFGDKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSP 401
Query: 370 K-------SVNRALQRIGRAGHRLHEV-SEGVIL 395
+ LQ +GRAG ++ EG+++
Sbjct: 402 EKGRWTELGALDILQMLGRAGRPQYDTKGEGILI 435
>dbj|BAA91812.1| (AK001652) unnamed protein product [Homo sapiens]
Length = 491
Score = 77.3 bits (187), Expect = 7e-13
Identities = 88/375 (23%), Positives = 154/375 (40%), Gaps = 43/375 (11%)
Query: 15 EEIYSILDPIVREWFKRKFKSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAIISE 74
++ Y I +++ F+ TP Q AI + G +L S+PTGSGKTL+ + I+ +
Sbjct: 59 DQEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQ 118
Query: 75 LISLGRRGKLEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRT 134
L +G + +SP R L + I R E+ ++S+ I I A
Sbjct: 119 LKQPANKG-----FRALIISPTRELASQIHR-------ELIKISEGTGFRIHMIHKAAVA 166
Query: 135 SDTSSYEKSKMLKMPPHILITTPESLAIALNAPRFREKLRDVKWVIVDEVHALAENKRGS 194
+ + SK IL+TTP L L L V+W++VDE L E+ +
Sbjct: 167 AKKFGPKSSKKF----DILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTG 222
Query: 195 HLALTLERLRELTKRDFVRIGLSATIHPLEEV---AKFVFGFSDDGKPRPGLIVDVSFAK 251
+ I L+ T H + A F + K ++ VS
Sbjct: 223 F------------RDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKLNLDNVISVSIGA 270
Query: 252 KTKITVESVVEDLVYTPANVLNEALYRRIGELVRS--RKTTLIFTNTRSGAERVAYHLKK 309
+ VE+V ++L++ + + ELV+ L+F + A+ + + L
Sbjct: 271 RNS-AVETVEQELLFVGSET---GKLLAVRELVKKGFNPPVLVFVQSIERAKELFHEL-- 324
Query: 310 MFPEWED-KIEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILIGS 368
+E ++ H+ +++ R + G++ +++ + L GID ++LVI
Sbjct: 325 ---IYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDF 381
Query: 369 PKSVNRALQRIGRAG 383
P S + RIGR G
Sbjct: 382 PTSSVEYIHRIGRTG 396
>dbj|BAB12216.1| (AB047802) vasa homolog [Ciona savignyi]
Length = 688
Score = 76.1 bits (184), Expect = 2e-12
Identities = 84/370 (22%), Positives = 157/370 (41%), Gaps = 28/370 (7%)
Query: 16 EIYSILDPIVREWFKRKFKSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAIISEL 75
E+ + + ++ + ++ TP Q+Y+I I+ +++ + TGSGKT + L ++++L
Sbjct: 234 EVAGLPETVLANVKRANYERPTPVQKYSIPIINADRDLMACAQTGSGKTAAFLLPVLTKL 293
Query: 76 ISLGRRGKLEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRTS 135
I+ G L+ + +P + R + + E R+ S+ +R V
Sbjct: 294 ITNG----LQSSQFSEKQTPRAIVVGPTRELIYQIFLEARKFSRG-----TVVRPVVAYG 344
Query: 136 DTSSYEKSKMLKMPPHILITTPESLAIALNAPRFREKLRDVKWVIVDEVHALAENKRGSH 195
TS + + L+ HILI TP L +N R L V++VI+DE + + +
Sbjct: 345 GTSMNHQIRDLQRGCHILIATPGRLMDFIN--RGLVGLDHVEFVILDEADRMLDMGFETE 402
Query: 196 LALTLERLRELTKRDFVRIGLSATIHPLEEVAKFVFGFSDDGKPRPGLIVDVSFAKKTKI 255
+ +K D + SAT +E+ + F L D F ++
Sbjct: 403 IRKLASSPGMPSKSDRHTLMFSATFP--DEIQRLAHDF---------LREDFLFLTVGRV 451
Query: 256 --TVESVVEDLVYTPANVLNEALYRRIGELVRSRKTTLIFTNTRSGAERVAYHLKKMFPE 313
V + ++ + L I ++ +R TL+F T+ GA+ +A L + E
Sbjct: 452 GGACTDVTQSIIQVDQDDKRAKLLELISDVAETRSRTLVFVETKRGADFLACMLSQ---E 508
Query: 314 WEDKIEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILIGSPKSVN 373
H L +E R + K I+++++ G+DI ++ VI PK ++
Sbjct: 509 GCPTTSIHGDRLQQE-REQALRDFKSAVCPILIATSVAARGLDIPKVEHVINYDMPKEID 567
Query: 374 RALQRIGRAG 383
+ RIGR G
Sbjct: 568 EYVHRIGRTG 577
>dbj|BAB12217.1| (AB047803) vasa homolog [Ciona savignyi]
Length = 770
Score = 76.1 bits (184), Expect = 2e-12
Identities = 84/370 (22%), Positives = 157/370 (41%), Gaps = 28/370 (7%)
Query: 16 EIYSILDPIVREWFKRKFKSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAIISEL 75
E+ + + ++ + ++ TP Q+Y+I I+ +++ + TGSGKT + L ++++L
Sbjct: 316 EVAGLPETVLANVKRANYERPTPVQKYSIPIINADRDLMACAQTGSGKTAAFLLPVLTKL 375
Query: 76 ISLGRRGKLEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRTS 135
I+ G L+ + +P + R + + E R+ S+ +R V
Sbjct: 376 ITNG----LQSSQFSEKQTPRAIVVGPTRELIYQIFLEARKFSRG-----TVVRPVVAYG 426
Query: 136 DTSSYEKSKMLKMPPHILITTPESLAIALNAPRFREKLRDVKWVIVDEVHALAENKRGSH 195
TS + + L+ HILI TP L +N R L V++VI+DE + + +
Sbjct: 427 GTSMNHQIRDLQRGCHILIATPGRLMDFIN--RGLVGLDHVEFVILDEADRMLDMGFETE 484
Query: 196 LALTLERLRELTKRDFVRIGLSATIHPLEEVAKFVFGFSDDGKPRPGLIVDVSFAKKTKI 255
+ +K D + SAT +E+ + F L D F ++
Sbjct: 485 IRKLASSPGMPSKSDRHTLMFSATFP--DEIQRLAHDF---------LREDFLFLTVGRV 533
Query: 256 --TVESVVEDLVYTPANVLNEALYRRIGELVRSRKTTLIFTNTRSGAERVAYHLKKMFPE 313
V + ++ + L I ++ +R TL+F T+ GA+ +A L + E
Sbjct: 534 GGACTDVTQSIIQVDQDDKRAKLLELISDVAETRSRTLVFVETKRGADFLACMLSQ---E 590
Query: 314 WEDKIEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILIGSPKSVN 373
H L +E R + K I+++++ G+DI ++ VI PK ++
Sbjct: 591 GCPTTSIHGDRLQQE-REQALRDFKSAVCPILIATSVAARGLDIPKVEHVINYDMPKEID 649
Query: 374 RALQRIGRAG 383
+ RIGR G
Sbjct: 650 EYVHRIGRTG 659
>gi|6321963 DEAD-box protein; Dbp8p [Saccharomyces cerevisiae]
>gi|731740|sp|P38719|DBP8_YEAST PROBABLE ATP-DEPENDENT
RNA HELICASE DBP8 >gi|626175|pir||S48908 helicase
homolog - yeast (Saccharomyces cerevisiae)
>gi|458901|gb|AAB68014.1| (U00027) Yhr169wp
[Saccharomyces cerevisiae]
Length = 431
Score = 75.7 bits (183), Expect = 2e-12
Identities = 88/366 (24%), Positives = 150/366 (40%), Gaps = 31/366 (8%)
Query: 37 TPPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAIISELISLGRRGKLEDKIYCVYVSPL 96
T Q+ I +I +G + + + TGSGKT+ AF + S G ++ V ++P
Sbjct: 26 TAIQKACIPKILEGRDCIGGAKTGSGKTI-AFAGPMLTKWSEDPSG-----MFGVVLTPT 79
Query: 97 RALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRTSDTSSYEKSKMLKMPPHILITT 156
R L I ++ L +N IRV+V S +++ L+ PH +I T
Sbjct: 80 RELAMQIA-------EQFTALGSSMN-----IRVSVIVGGESIVQQALDLQRKPHFIIAT 127
Query: 157 PESLA--IALNAPRFREKLRDVKWVIVDEVHALAENKRGSHLALTLERLRELTKRDFVRI 214
P LA I + L K++++DE L + HLA + L KR +
Sbjct: 128 PGRLAHHIMSSGDDTVGGLMRAKYLVLDEADILLTSTFADHLATCISALPPKDKRQTLLF 187
Query: 215 GLSATIHPLEEVAKFVFGFSDDGKPRPGLIVDVSFAKKTKITVESVVEDLVYTPANVLNE 274
+ T ++V GKP P V I +E + P +V
Sbjct: 188 TATIT----DQVKSLQNAPVQKGKP-PLFAYQVESVDNVAIPSTLKIE-YILVPEHVKEA 241
Query: 275 ALYRRIGELVRSRKTTLIFTNTRSGAERVAYHLKKMFPEWEDKIEAHHSSLSREVRLEVE 334
LY+ + KT +IF N AE + LK++ E ++ + HS + ++ R
Sbjct: 242 YLYQLLTCEEYENKTAIIFVNRTMTAEILRRTLKQL----EVRVASLHSQMPQQERTNSL 297
Query: 335 ERLKRGELKIIVSSTSLELGIDIGTIDLVILIGSPKSVNRALQRIGRAGHRLHEVSEGVI 394
R + +I++++ G+DI T++LV+ P + + R GR R + + +
Sbjct: 298 HRFRANAARILIATDVASRGLDIPTVELVVNYDIPSDPDVFIHRSGRTA-RAGRIGDAIS 356
Query: 395 LALDRD 400
RD
Sbjct: 357 FVTQRD 362
>gb|AAF55204.1| (AE003709) CG5205 gene product [Drosophila melanogaster]
Length = 1809
Score = 74.9 bits (181), Expect = 3e-12
Identities = 87/358 (24%), Positives = 151/358 (41%), Gaps = 57/358 (15%)
Query: 45 VEIHKGENVLISSPTGSGKTLSAFLAIISELISLGRRGKL-EDKIYCVYVSPLRALNNDI 103
V H EN+L+ +PTG+GKT A L+I+ + +G + D+ VY++P++AL ++
Sbjct: 123 VAYHSNENMLVCAPTGAGKTNVAMLSIVHTIRCHLEQGVINRDEFKIVYIAPMKALAAEM 182
Query: 104 RRNLEEPLQEIRELSQELNEEIPEIRVAVRTSDTSSYEKSKMLKMPPHILITTPESLAIA 163
N + L+ ++ +EL T + +K IL+TTPE +
Sbjct: 183 VDNFSKRLKSLQIAVREL---------------TGDIQLTKAEMAATQILVTTPEKWDVV 227
Query: 164 LNAPRFREKLRD-VKWVIVDEVHALAENKRGSHLALTLERLREL--TKRDFVRI-GLSAT 219
L V+ +I+DEVH L +RG + + R L + + +RI GLSAT
Sbjct: 228 TRKGSGDVALISLVELLIIDEVH-LLHGERGPVVEALVARTLRLVESSQSMIRIVGLSAT 286
Query: 220 IHPLEEVAKF--------VFGFSDDGKPRPGLIVDVSFAKKTKI---------------- 255
+ +VA F +F F +P P +D +F +
Sbjct: 287 LPNYIDVAHFLRVNPMKGLFYFDSRFRPVP---LDTNFVGIKSVKQLQQIADMDQCCYQK 343
Query: 256 TVESVVED---LVYTPANVLNEALYRRIGELVRSRKTTLIFTNTRSGAERVAYHL----- 307
VE V E +V+ A I EL + T+ +F S A +A
Sbjct: 344 CVEMVQEGHQIMVFVHARNATVRTANVIRELAQQNNTSALFLPKDSAAHGLATRSIQRSR 403
Query: 308 -KKMFPEWEDKIEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVI 364
K++ + + HH+ + R R VE+ G + ++V + +L G+++ ++I
Sbjct: 404 NKQLVELFSCGLAMHHAGMLRADRQMVEKYFVEGHISVLVCTATLAWGVNLPAHAVII 461
>dbj|BAA19572.1| (D86601) DEAD family RNA helicase; germ cell specific in Bombyx 5th
instar larva, a material factor [Bombyx mori]
Length = 601
Score = 74.1 bits (179), Expect = 6e-12
Identities = 93/376 (24%), Positives = 159/376 (41%), Gaps = 55/376 (14%)
Query: 20 ILDPIVREWFKRKFKSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAIISELIS-- 77
+LD +++ +++ TP Q+ AI I G +++ + TGSGKT + + II+ L+
Sbjct: 191 VLDNVLKAGYRKP----TPIQKNAIPIIMSGRDLMGCAQTGSGKTAAFLVPIINMLLQDP 246
Query: 78 ---LGRRGKLEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRT 134
+ G + ++ + VSP R L I E R+ S ++VAV
Sbjct: 247 KDLISENGCAQPQV--IIVSPTRELTLQI-------FNEARKFSYG-----SVLKVAVAY 292
Query: 135 SDTSSYEKSKMLKMPPHILITTPESLAIALNAPRFREKLRDVKWVIVDEVHALAENKRGS 194
T+ + + HIL+ TP L + R R V++V++DE A+
Sbjct: 293 GGTAVRHQGDNIARGCHILVATPGRLHDFVE--RNRVSFGSVRFVVLDE----ADRMLDM 346
Query: 195 HLALTLERLR------ELTKRDFVRIGLSATIHPLEEVAKFVFGFSDDGKPRPGLIVDVS 248
++E++ E TKR + SAT E++ F ++ L V V
Sbjct: 347 GFMPSIEKMMLHPTMVETTKRQTLMF--SATFP--EDIQHLAGRFLNNY-----LFVAVG 397
Query: 249 FAKKTKITVESV-VEDLVYTPANVLNEALYRRIGELVRSRKTTLIFTNTRSGAERVAYHL 307
VE + +E Y N L + + G K L+F T+ A+ +A
Sbjct: 398 IVGGASTDVEQIFIEVTKYEKRNSLKQLIEENDG------KRILVFVETKRNADFIA--- 448
Query: 308 KKMFPEWEDKIEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILIG 367
M E + + H + R E + K G+ I+V++ G+DI +D+V+
Sbjct: 449 -AMLSEQQLLTSSIHGDRMQREREEALQNFKSGKHCILVATAVAARGLDIKNVDIVVNYD 507
Query: 368 SPKSVNRALQRIGRAG 383
PKS++ + RIGR G
Sbjct: 508 LPKSIDEYVHRIGRTG 523
>pir||T40504 atp-dependent, dead box, rna helicase - fission yeast
(Schizosaccharomyces pombe) >gi|3560140|emb|CAA20727.1|
(AL031534) atp-dependent, dead box, rna helicase
[Schizosaccharomyces pombe]
Length = 648
Score = 74.1 bits (179), Expect = 6e-12
Identities = 102/441 (23%), Positives = 179/441 (40%), Gaps = 53/441 (12%)
Query: 7 WANREYSDEEIYSILDPIVREWFKRKFKSFTPPQRYAIVEIHKGENVLISSPTGSGKTLS 66
WA+ S E + S+ K F P Q I E G +++ + TGSGKTL+
Sbjct: 124 WAHFSLSPEMLGSLS--------KAGFSKPMPIQSLVIPEASIGFDIIGKADTGSGKTLA 175
Query: 67 AFLAIISELISLGRRGKLEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIP 126
+ I+ + R + + V+P R L + I ++ E L + P
Sbjct: 176 FGIPILEHCL----RNVDAKYVQALVVAPTRELAHQICQHFE------------LIKPSP 219
Query: 127 EIRVAVRTSDTSSYEKSKMLKMPPHILITTPESLAIALNAPRFREKLRDVKWVIVDEVHA 186
IRV T + ++ ++L PH+++ TP L +N + +K +++DE
Sbjct: 220 NIRVMSITGGLAVQKQQRLLNKHPHVVVATPGRLWSVINENNLTGNFKKIKCLVLDEADR 279
Query: 187 LAENKRGSHLALTLERLRELTKRDFVRIGLSATIHP--LEEVAKFVFGFSDD--GKPRPG 242
L + L+ LE L SAT + + K + G + P
Sbjct: 280 LLQKSHFEELSKLLEILGNPMHTQRQTFIFSATFDEGLQQRLKKNMKGNITEKYNSPMEN 339
Query: 243 LIVDVSFAKKTKI--------TVESVVEDLVYTPANVLNEALYRRIGELVRSRKTTLIFT 294
++ +V F K K V+E L+ + LY I +R T++F
Sbjct: 340 MLKEVRFFGKPKFLDANPQSAVASRVLEGLIECAPAEKDLYLYYLI---MRYPGKTMVFA 396
Query: 295 NTRSGAERVAYHLKKMFPEWEDKIEAH--HSSLSREVRLEVEERLKRGELKIIVSSTSLE 352
N +R+ L ++ K+ ++ H+ L ++ RL+ E+ K ++V +
Sbjct: 397 NGIEDIKRITPFLNEL------KVPSYPLHAQLDQKKRLQSLEKFKNNPKGVLVCTDVAA 450
Query: 353 LGIDIGTIDLVILIGSPKSVNRALQRIGRAGHRLHEVSEGV-ILALDRDDLVEVTVLAHN 411
GIDI ++ VI P + + + R GR R +E +GV IL +L ++ L +
Sbjct: 451 RGIDIPSVTHVIHYHVPHTADMYVHRSGRTA-RANE--DGVSILMCGPKELSQLKRLCYR 507
Query: 412 ARKRKLDRIKIP--KNPLDVL 430
+K+ I P + LD+L
Sbjct: 508 LKKKIETFINFPVDMSILDIL 528
>pir||S01676 ATP-dependent RNA helicase homolog - fruit fly (Drosophila
melanogaster)
Length = 660
Score = 73.4 bits (177), Expect = 1e-11
Identities = 87/365 (23%), Positives = 155/365 (41%), Gaps = 41/365 (11%)
Query: 22 DPIVREWFKRKFKSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAIISELISLGRR 81
D I+ K FK TP Q+ +I I G +++ + TGSGKT + L I+S+L+
Sbjct: 254 DIIIDNVNKSGFKIPTPIQKCSIPVISSGRDLMACAQTGSGKTAAFLLPILSKLLEDPHE 313
Query: 82 GKLEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRTSDTSSYE 141
+L + V VSP R L I E R+ + E +++ + TS
Sbjct: 314 LEL-GRPQVVIVSPTRELAIQI-------FNEARKFAFE-----SYLKIGIVYGGTSFRH 360
Query: 142 KSKMLKMPPHILITTPESLAIALNAPRFREKLRDVKWVIVDEVHALAENKRGSHLALTLE 201
+++ + H++I TP L ++ R D ++V++DE +
Sbjct: 361 QNECITRGCHVVIATPGRLLDFVD--RTFITFEDTRFVVLDEA----------------D 402
Query: 202 RLREL-TKRDFVRIGLSATIHPLEEVAKFVFGFSDDGKPRPGLIVDVSFAKKTKITVESV 260
R+ ++ D RI T+ P + F F ++ + G + + F V
Sbjct: 403 RMLDMGFSEDMRRIMTHVTMRPEHQTLMFSATFPEEIQRMAGEFLKLRFVAIG--IVGGR 460
Query: 261 VEDLVYTPANVLNEALYRRIGELVRSRKT-TLIFTNTRSGAERVAYHL-KKMFPEWEDKI 318
D+ T V A ++ E++ + T++F T+ GA+ +A L +K FP
Sbjct: 461 CSDVKQTIYEVNKYAKRSKLIEILSEQADGTIVFVETKRGADFLASFLSEKEFP-----T 515
Query: 319 EAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILIGSPKSVNRALQR 378
+ H + R + K G +K++++++ G+DI I VI P ++ + R
Sbjct: 516 TSIHGDRLQSQREQALRDFKNGSMKVLIATSVASRGLDIKNIKHVINYDMPSKIDDYVHR 575
Query: 379 IGRAG 383
IGR G
Sbjct: 576 IGRTG 580
>pir||A31922 ATP-dependent RNA helicase homolog - fruit fly (Drosophila
melanogaster) >gi|158796|gb|AAA29013.1| (M23560) Mab4611
antigen (vasa) [Drosophila melanogaster]
Length = 648
Score = 73.0 bits (176), Expect = 1e-11
Identities = 87/369 (23%), Positives = 155/369 (41%), Gaps = 48/369 (13%)
Query: 22 DPIVREWFKRKFKSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAIISELISLGRR 81
D I+ K +K TP Q+ +I I G +++ + TGSGKT + L I+S+L+
Sbjct: 241 DIIIDNVNKSGYKIPTPIQKCSIPVISSGRDLMACAQTGSGKTAAFLLPILSKLLEDPHE 300
Query: 82 GKLEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRTSDTSSYE 141
+L C+ VSP R L I E R+ + E +++ + TS
Sbjct: 301 LELGRPQVCI-VSPTRELAIQI-------FNEARKFAFE-----SYLKIGIVYGGTSFRH 347
Query: 142 KSKMLKMPPHILITTPESLAIALNAPRFREKLRDVKWVIVDEVHALAENKRGSHLALTLE 201
+++ + H++I TP L ++ R D ++V++DE +
Sbjct: 348 QNECITRGCHVVIATPGRLLDFVD--RTFITFEDTRFVVLDEA----------------D 389
Query: 202 RLRELT-KRDFVRIGLSATIHPLEEVAKFVFGFSDDGKPRPGLIVDVSFAKKTKITVESV 260
R+ ++ D RI T+ P + F F ++ + G F K +
Sbjct: 390 RMLDMGFSEDMRRIMTHVTMRPEHQTLMFSATFPEEIQRMAG-----EFLKNYVFVAIGI 444
Query: 261 V----EDLVYTPANVLNEALYRRIGELVRSRKT-TLIFTNTRSGAERVAYHL-KKMFPEW 314
V D+ T V A ++ E++ + T++F T+ GA+ +A L +K FP
Sbjct: 445 VGGACSDVKQTIYEVNKYAKRSKLIEILSEQADGTIVFVETKRGADFLASFLSEKEFPT- 503
Query: 315 EDKIEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILIGSPKSVNR 374
+ H + R + K G +K++++++ G+DI I VI P ++
Sbjct: 504 ----TSIHGDRLQSQREQALRDFKNGSMKVLIATSVASRGLDIKNIKHVINYDMPSKIDD 559
Query: 375 ALQRIGRAG 383
+ RIGR G
Sbjct: 560 YVHRIGRTG 568
>prf||1413329A gene vasa [Drosophila melanogaster]
Length = 660
Score = 73.0 bits (176), Expect = 1e-11
Identities = 87/368 (23%), Positives = 157/368 (42%), Gaps = 47/368 (12%)
Query: 22 DPIVREWFKRKFKSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAIISELISLGRR 81
D I+ K FK TP Q+ +I I G +++ + TGSGKT + L I+S+L+
Sbjct: 254 DIIIDNVNKSGFKIPTPIQKCSIPVISSGRDLMACAQTGSGKTAAFLLPILSKLLEDPHE 313
Query: 82 GKLEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRTSDTSSYE 141
+L + V VSP R L I E R+ + E +++ + TS
Sbjct: 314 LEL-GRPQVVIVSPTRELAIQI-------FNEARKFAFE-----SYLKIGIVYGGTSFRH 360
Query: 142 KSKMLKMPPHILITTPESLAIALNAPRFREKLRDVKWVIVDEVHALAENKRGSHLALTLE 201
+++ + H++I TP L ++ R D ++V++DE +
Sbjct: 361 QNECITRGCHVVIATPGRLLDFVD--RTFITFEDTRFVVLDEA----------------D 402
Query: 202 RLREL-TKRDFVRIGLSATIHPLEEVAKFVFGFSDDGKPRPGLIVDVSFAKKTKITVESV 260
R+ ++ D RI T+ P + F F ++ + G + + F V
Sbjct: 403 RMLDMGFSEDMRRIMTHVTMRPEHQTLMFSATFPEEIQRMAGEFLKLRFVAIG--IVGGR 460
Query: 261 VEDLVYTPANVLNEALYRRIGELVRSRKT-TLIFTNTRSGAERVAYHL-KKMFPEWE--- 315
D+ T V A ++ E++ + T++F T+ GA+ +A L +K FP
Sbjct: 461 CSDVKQTIYEVNKYAKRSKLIEILSEQADGTIVFVETKRGADFLASFLSEKEFPTTSIRG 520
Query: 316 DKIEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILIGSPKSVNRA 375
D++++ R+ K G +K++++++ G+DI I VI P ++
Sbjct: 521 DRLQSQREQALRD--------FKNGSMKVLIATSVASRGLDIKNIKHVINYDMPSKIDDY 572
Query: 376 LQRIGRAG 383
+ RIGR G
Sbjct: 573 VHRIGRTG 580
>sp|P09052|VASA_DROME VASA PROTEIN >gi|7446078|pir||A58768 ATP-dependent RNA helicase
homolog - fruit fly (Drosophila melanogaster)
>gi|1054723|emb|CAA31405.1| (X12945) vasa [Drosophila
melanogaster]
Length = 661
Score = 73.0 bits (176), Expect = 1e-11
Identities = 86/365 (23%), Positives = 155/365 (41%), Gaps = 40/365 (10%)
Query: 22 DPIVREWFKRKFKSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAIISELISLGRR 81
D I+ K FK TP Q+ +I I G +++ + TGSGKT + L I+S+L+
Sbjct: 254 DIIIDNVNKSGFKIPTPIQKCSIPVISSGRDLMACAQTGSGKTAAFLLPILSKLLEDPHE 313
Query: 82 GKLEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRTSDTSSYE 141
+L + V VSP R L I E R+ + E +++ + TS
Sbjct: 314 LEL-GRPQVVIVSPTRELAIQI-------FNEARKFAFE-----SYLKIGIVYGGTSFRH 360
Query: 142 KSKMLKMPPHILITTPESLAIALNAPRFREKLRDVKWVIVDEVHALAENKRGSHLALTLE 201
+++ + H++I TP L ++ R D ++V++DE +
Sbjct: 361 QNECITRGCHVVIATPGRLLDFVD--RTFITFEDTRFVVLDEA----------------D 402
Query: 202 RLREL-TKRDFVRIGLSATIHPLEEVAKFVFGFSDDGKPRPGLIVDVSFAKKTKITVESV 260
R+ ++ D RI T+ P + F F ++ + G + ++ V
Sbjct: 403 RMLDMGFSEDMRRIMTHVTMRPEHQTLMFSATFPEEIQRMAGEFLK-NYVSVAIGIVGGA 461
Query: 261 VEDLVYTPANVLNEALYRRIGELVRSRKT-TLIFTNTRSGAERVAYHL-KKMFPEWEDKI 318
D+ T V A ++ E++ + T++F T+ GA+ +A L +K FP
Sbjct: 462 CSDVKQTIYEVNKYAKRSKLIEILSEQADGTIVFVETKRGADFLASFLSEKEFP-----T 516
Query: 319 EAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILIGSPKSVNRALQR 378
+ H + R + K G +K++++++ G+DI I VI P ++ + R
Sbjct: 517 TSIHGDRLQSQREQALRDFKNGSMKVLIATSVASRGLDIKNIKHVINYDMPSKIDDYVHR 576
Query: 379 IGRAG 383
IGR G
Sbjct: 577 IGRTG 581
>gb|AAF39890.1| (AC006661) contains similarity to Pfam families PF00270 (DEAD/DEAH
box helicase, score=162.5, E=1.8e-50, N=2) and PF00271
(Helicases conserved C-terminal domain, score=104.4,
E=2.2e-27, N=1) [Caenorhabditis elegans]
Length = 696
Score = 71.8 bits (173), Expect = 3e-11
Identities = 92/427 (21%), Positives = 176/427 (40%), Gaps = 46/427 (10%)
Query: 15 EEIYSILDPIVREWFKRKFKSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAIISE 74
E++ D I++ F K F+ R+ +I K + TG+GKTL+ + I+ +
Sbjct: 150 EKLLKFNDKILK--FPLKINKFSRKIRFFYRKIKKTTEEKCCARTGTGKTLAFAIPILQK 207
Query: 75 LISLGRRGKLEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRT 134
L S+ G IY + ++P R L +I E L + I ++ +V
Sbjct: 208 L-SVDPYG-----IYALILTPTREL-----------AFQIAEQFTALGKPIT-LKCSVIV 249
Query: 135 SDTSSYEKSKMLKMPPHILITTPESLA--IALNAPRFREKLRDVKWVIVDEVHALAENKR 192
S +++ L PH+++ TP LA I + + + +++ ++DE + E +
Sbjct: 250 GGRSLIHQARELSERPHVVVATPGRLADLIESDPDTIAKVFKKIQFFVLDEADRMLEGQY 309
Query: 193 GSHLALTLERLRELTKRDFVRIGLSATIHPLEEVA-KFVFGFSDDGKPRPGLIVDVSFAK 251
L E + E + + ++ I+ L V+ + + F D GK
Sbjct: 310 NDQLKPIFESISEKRQTLLLSATITNNINMLHRVSTRKPYFFEDKGKD------------ 357
Query: 252 KTKITVESVVEDLVYTPANVLNEALYRRIGELVRS--RKTTLIFTNTRSGAERVAYHLKK 309
+ TV+ + + V P V + L + + + +IF T + +AY
Sbjct: 358 -DESTVDRLEQKYVVCPVAVKDAYLVYVVKNYSEKNPKSSVMIFAQTCRECQALAY---- 412
Query: 310 MFPEWEDKIEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILIGSP 369
MF ++ + HS + ++ RL + L++I+ + G+DI +DLV+ P
Sbjct: 413 MFEGLGFRVGSLHSQIPQKQRLAALSAFRSKTLQVIICTDVASRGLDIPHVDLVVNHNVP 472
Query: 370 KSVNRALQRIGRAGHRLHEVSEGVILALDRDDLVEVTVLAHNARKRKLDRIKI-PKNPLD 428
+ + R+GR+ R + D VE+ +KLD +K+ PK+
Sbjct: 473 QCPKTYIHRVGRSA-RAGRFGSALSFVTQYD--VELLQAVEQVIGKKLDELKVSPKHVTK 529
Query: 429 VLVQHLL 435
+ Q L+
Sbjct: 530 YVTQVLV 536
>pir||B45065 probable helicase - Escherichia coli (fragment)
Length = 130
Score = 71.4 bits (172), Expect = 4e-11
Identities = 40/117 (34%), Positives = 60/117 (51%), Gaps = 4/117 (3%)
Query: 20 ILDPIVREWFKRKFKSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAIISELISLG 79
+ P R+WF R FK T Q + E+ L+ +PTGSGKTL+AFL + L G
Sbjct: 14 VFSPATRDWFLRAFKQPTAVQPQTWHVAARSEHALVIAPTGSGKTLAAFLYALDRLFREG 73
Query: 80 ----RRGKLEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAV 132
R +Y+SP++AL D++RNL+ PL+ I + + E +RV +
Sbjct: 74 GEDTREAHKRKTSRILYISPIKALGTDVQRNLQIPLKGIADERRRRGETEVNLRVGI 130
>emb|CAA09374.1| (AJ010840) ATP-dependent RNA helicase [Homo sapiens]
Length = 420
Score = 71.4 bits (172), Expect = 4e-11
Identities = 84/354 (23%), Positives = 142/354 (39%), Gaps = 37/354 (10%)
Query: 33 FKSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAIISELISLGRRGKLEDKIYCVY 92
F+ TP Q AI + G +L S+PTGSGKTL+ + I+ +L +G +
Sbjct: 6 FQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLKQPANKG-----FRALI 60
Query: 93 VSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRTSDTSSYEKSKMLKMPPHI 152
+SP R L + I R E+ ++S+ I I A + + SK I
Sbjct: 61 ISPTRELASQIHR-------ELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKF----DI 109
Query: 153 LITTPESLAIALNAPRFREKLRDVKWVIVDEVHALAENKRGSHLALTLERLRELTKRDFV 212
L+TTP L L L V+W++VDE L E+ + T
Sbjct: 110 LVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVR 169
Query: 213 RIGLSATIHPLEEVAKFVFGFSDDGKPRPGLIVDVSFAKKTKITVESVVEDLVYTPANVL 272
R SA +H + + G + V VE+V ++L++ +
Sbjct: 170 RAMFSAILHMM----------LNSGANSTWTMSSVCPFGARNSAVETVEQELLFVGSET- 218
Query: 273 NEALYRRIGELVRS--RKTTLIFTNTRSGAERVAYHLKKMFPEWED-KIEAHHSSLSREV 329
+ ELV+ L+F + A+ + + L +E ++ H+ +++
Sbjct: 219 --GKLLAVRELVKKGFNPPVLVFVQSIERAKELFHEL-----IYEGINVDVIHAERTQQQ 271
Query: 330 RLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILIGSPKSVNRALQRIGRAG 383
R + G++ +++ + L GID ++LVI P S + RIGR G
Sbjct: 272 RDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTG 325
>gi|4759030 RecQ protein-like 4; RecQ protein 4 [Homo sapiens]
>gi|4191810|dbj|BAA74453.1| (AB006532) DNA helicase
[Homo sapiens] >gi|6440969|dbj|BAA86899.1| (AB026546)
RECQL4 helicase [Homo sapiens]
Length = 1208
Score = 71.4 bits (172), Expect = 4e-11
Identities = 89/395 (22%), Positives = 162/395 (40%), Gaps = 58/395 (14%)
Query: 34 KSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAIISELISLGRRGKLEDKIYCVYV 93
++F P Q A++ I G + L+ PTG+GK+L L + RR + V
Sbjct: 479 QAFRPGQERAVMRILSGISTLLVLPTGAGKSLCYQLPALL----YSRRSPC----LTLVV 530
Query: 94 SPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRTSDTSSYEKSKMLKMPPHIL 153
SPL +L +D L L+ S ++ + +R + H+L
Sbjct: 531 SPLLSLMDDQVSGLPPCLKAACIHSGMTRKQRESVLQKIRAAQV-------------HVL 577
Query: 154 ITTPESLAIALNAPRFREKLRDVKWVIVDEVHALAE---NKRGSHLALTLERLRELTKRD 210
+ TPE+L A P + L V + +DE H L++ N R +L + +
Sbjct: 578 MLTPEALVGAGGLPPAAQ-LPPVAFACIDEAHCLSQWSHNFRPCYLRVCKVLRERMGVHC 636
Query: 211 FVRIGLSATIHPLEEVAKF--VFGFSDDGKPRP---GLIVDVSFAKKTKITVESVVEDLV 265
F+ + +AT +VA+ V D P P L + VS + T + ++++
Sbjct: 637 FLGLTATATRRTASDVAQHLAVAEEPDLHGPAPVPTNLHLSVSMDRDTDQALLTLLQ--- 693
Query: 266 YTPANVLNEALYRRIGELVRSRKTTLIFTNTRSGAERVAYHLKK-MFPEW---------E 315
G+ ++ + +I+ N R ER+A L+ + W +
Sbjct: 694 ---------------GKRFQNLDSIIIYCNRREDTERIAALLRTCLHAAWVPGSGGRAPK 738
Query: 316 DKIEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILIGSPKSVNRA 375
EA+H+ + R V+ +G+L+++V++ + +G+D + V+ +G P S
Sbjct: 739 TTAEAYHAGMCSRERRRVQRAFMQGQLRVVVATVAFGMGLDRPDVRAVLHLGLPPSFESY 798
Query: 376 LQRIGRAGHRLHEVSEGVILALDRDDLVEVTVLAH 410
+Q +GRAG + L +DL E+ H
Sbjct: 799 VQAVGRAGRDGQPAHCHLFLQPQGEDLRELRRHVH 833
>gb|AAF44917.1|AE003406_122 (AE003416) symbol=vas; synonym=BG:DS00929.14; cDNA=method:''sim4'',
score:''1000.0'', desc:''LD06084 LD Drosophila
melanogaster embryo BlueScript Drosophila melanogaster
cDNA clone LD06084 5prime, mRNA sequence:AA246989'';
match=method:''sim4'', score:>
>gi|7298204|gb|AAF53438.1| (AE003646) vas gene product
[Drosophila melanogaster]
Length = 661
Score = 71.4 bits (172), Expect = 4e-11
Identities = 87/369 (23%), Positives = 155/369 (41%), Gaps = 48/369 (13%)
Query: 22 DPIVREWFKRKFKSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAIISELISLGRR 81
D I+ K +K TP Q+ +I I G +++ + TGSGKT + L I+S+L+
Sbjct: 254 DIIIDNVNKSGYKIPTPIQKCSIPVISSGRDLMACAQTGSGKTAAFLLPILSKLLEDPHE 313
Query: 82 GKLEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRTSDTSSYE 141
+L + V VSP R L I E R+ + E +++ + TS
Sbjct: 314 LEL-GRPQVVIVSPTRELAIQI-------FNEARKFAFE-----SYLKIGIVYGGTSFRH 360
Query: 142 KSKMLKMPPHILITTPESLAIALNAPRFREKLRDVKWVIVDEVHALAENKRGSHLALTLE 201
+++ + H++I TP L ++ R D ++V++DE +
Sbjct: 361 QNECITRGCHVVIATPGRLLDFVD--RTFITFEDTRFVVLDEA----------------D 402
Query: 202 RLRELT-KRDFVRIGLSATIHPLEEVAKFVFGFSDDGKPRPGLIVDVSFAKKTKITVESV 260
R+ ++ D RI T+ P + F F ++ + G F K +
Sbjct: 403 RMLDMGFSEDMRRIMTHVTMRPEHQTLMFSATFPEEIQRMAG-----EFLKNYVFVAIGI 457
Query: 261 V----EDLVYTPANVLNEALYRRIGELVRSRKT-TLIFTNTRSGAERVAYHL-KKMFPEW 314
V D+ T V A ++ E++ + T++F T+ GA+ +A L +K FP
Sbjct: 458 VGGACSDVKQTIYEVNKYAKRSKLIEILSEQADGTIVFVETKRGADFLASFLSEKEFPT- 516
Query: 315 EDKIEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILIGSPKSVNR 374
+ H + R + K G +K++++++ G+DI I VI P ++
Sbjct: 517 ----TSIHGDRLQSQREQALRDFKNGSMKVLIATSVASRGLDIKNIKHVINYDMPSKIDD 572
Query: 375 ALQRIGRAG 383
+ RIGR G
Sbjct: 573 YVHRIGRTG 581
>dbj|BAA34994.1| (AB017003) DjVLGB [Dugesia japonica]
Length = 781
Score = 71.0 bits (171), Expect = 5e-11
Identities = 88/396 (22%), Positives = 168/396 (42%), Gaps = 42/396 (10%)
Query: 21 LDPIVRE-WFKRKFKSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAIISELISLG 79
LDP +R ++ TP Q+ AI I + +++ + TGSGKT + + II+ L+
Sbjct: 191 LDPTIRNNILLASYQRPTPIQKNAIPAILEHRDIMACAQTGSGKTAAFLIPIINHLVCQD 250
Query: 80 RRGKLEDKIY---CVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRTSD 136
+ K C+ ++P R L +Q + E SQ+ + P +R V
Sbjct: 251 LNQQRYSKTAYPKCLILAPTREL----------AIQILSE-SQKFSLNTP-LRSCVVYGG 298
Query: 137 TSSYEKSKMLKMPPHILITTPESLAIALNAPRFREKLRDVKWVIVDEVHALAENKRGSHL 196
++ + + ++M H+L+ TP L + + L K++++DE + + +
Sbjct: 299 ADTHSQIREVQMGCHLLVATPGRLVDFIEKNKI--SLEFCKYIVLDEADRMLDMGFEPQI 356
Query: 197 ALTLERLRELTKRDFVRIGLSATIHPLEEVAKFVFGFSDDGKPRPGLIVDVSFAKKTKI- 255
+E + + + SAT +E+ K F + + F ++
Sbjct: 357 RKIIEESNMPSGINRQTLMFSATFP--KEIQKLAADF----------LYNYIFMTVGRVG 404
Query: 256 -TVESVVEDLVY-TPANVLNEALYRRIGELVRSRKTTLIFTNTRSGAERVA-YHLKKMFP 312
T +S+ ++++Y T LN + I LIF T+ GA+ +A + L K +P
Sbjct: 405 STSDSIKQEIIYMTDVEKLN--YLKNIFNTTAPNTLILIFVETKKGADSLARFLLSKGYP 462
Query: 313 EWEDKIEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILIGSPKSV 372
I S + RE L + + G+ I+V++ G+DI + VI P +
Sbjct: 463 V--SSIHGDRSQVEREAALSM---FRNGQCPILVATAVAARGLDIPNVKHVINYDLPSDI 517
Query: 373 NRALQRIGRAGHRLHEVSEGVILALDRDDLVEVTVL 408
+ RIGR G RL +D+++ + + ++
Sbjct: 518 EEYVHRIGRTG-RLGNHGRATSFYVDKNNNIAIDLV 552
>sp|P25888|RHLE_ECOLI PUTATIVE ATP-DEPENDENT RNA HELICASE RHLE >gi|7446107|pir||E64816
probable ATP-dependent RNA helicase rhlE - Escherichia
coli >gi|560801|gb|AAA53653.1| (L02123) ATP-dependent
RNA helicase [Escherichia coli]
>gi|1651360|dbj|BAA35463.1| (D90717) Putative
ATP-dependent RNA helicase RhlE. [Escherichia coli]
>gi|1787016|gb|AAC73884.1| (AE000182) putative
ATP-dependent RNA helicase [Escherichia coli K12]
>gi|4062355|dbj|BAA35457.1| (D90716) Putative
ATP-dependent RNA helicase RhlE. [Escherichia coli]
Length = 454
Score = 70.6 bits (170), Expect = 7e-11
Identities = 96/406 (23%), Positives = 170/406 (41%), Gaps = 49/406 (12%)
Query: 24 IVREWFKRKFKSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAIISELISLGRRGK 83
I+R ++ ++ TP Q+ AI + +G +++ S+ TG+GKT L ++ LI+ K
Sbjct: 12 ILRAVAEQGYREPTPIQQQAIPAVLEGRDLMASAQTGTGKTAGFTLPLLQHLITRQPHAK 71
Query: 84 LEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRTSDTSSYEKS 143
+ + ++P R L I N +R+ S+ LN IR V S +
Sbjct: 72 GRRPVRALILTPTRELAAQIGEN-------VRDYSKYLN-----IRSLVVFGGVSINPQM 119
Query: 144 KMLKMPPHILITTPESLAIALNAPRFREKLRDVKWVIVDEVHALAENKRGSHLALTLERL 203
L+ +L+ TP L + + KL V+ +++DE + + + +
Sbjct: 120 MKLRGGVDVLVATPGRLLDLEH--QNAVKLDQVEILVLDEADRMLD------MGFIHDIR 171
Query: 204 RELTKRDFVRIGLSATIHPLEEVAKFVFGFSDDGKPRPGLI----VDVSFAKKTKITVES 259
R LTK R L F FSDD K + +++ A++ + +
Sbjct: 172 RVLTKLPAKRQNL-----------LFSATFSDDIKALAEKLLHNPLEIEVARRNTAS-DQ 219
Query: 260 VVEDLVYTPANVLNEALYRRIGELVRSRKTTLIFTNTRSGAERVAYHLKKMFPEWEDKIE 319
V + + + E L IG+ + + L+FT T+ GA +A L K D I
Sbjct: 220 VTQHVHFVDKKRKRELLSHMIGK--GNWQQVLVFTRTKHGANHLAEQLNK------DGIR 271
Query: 320 --AHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILIGSPKSVNRALQ 377
A H + S+ R K G+++++V++ G+DI + V+ P +
Sbjct: 272 SAAIHGNKSQGARTRALADFKSGDIRVLVATDIAARGLDIEELPHVVNYELPNVPEDYVH 331
Query: 378 RIGRAGHRLHEVSEGVILALDRDDLVEVTVLAHNARKRKLDRIKIP 423
RIGR G + G L+L D ++ K+++ RI IP
Sbjct: 332 RIGRTG---RAAATGEALSLVCVDEHKLLRDIEKLLKKEIPRIAIP 374
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.320 0.138 0.388
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 306033929
Number of Sequences: 2977
Number of extensions: 13013872
Number of successful extensions: 41505
Number of sequences better than 1.0e-10: 77
Number of HSP's better than 0.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 53
Number of HSP's that attempted gapping in prelim test: 41166
Number of HSP's gapped (non-prelim): 108
length of query: 867
length of database: 189,106,746
effective HSP length: 60
effective length of query: 807
effective length of database: 153,197,526
effective search space: 123630403482
effective search space used: 123630403482
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 169 (70.2 bits)