BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0746 (PAB0746) DE:OVCA1=CANDIDATE TUMOR SUPPRESSOR related
(339 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||B75092 conserved hypothetical protein PAB0746 - Pyrococcus ... 689 0.0
pir||B71051 conserved hypothetical protein PH1105 - Pyrococcus h... 564 e-160
gi|11499391 conserved hypothetical protein [Archaeoglobus fulgid... 238 7e-62
pir||C69042 conserved hypothetical protein MTH1319 - Methanobact... 238 7e-62
gb|AAG19302.1| (AE005026) Vng0854c [Halobacterium sp. NRC-1] 213 2e-54
gb|AAK40633.1| Conserved hypothetical protein [Sulfolobus solfat... 185 6e-46
sp|Q57907|Y483_METJA HYPOTHETICAL PROTEIN MJ0483 >gi|2128012|pir... 168 7e-41
emb|CAC11400.1| (AL445063) hypothetical protein [Thermoplasma ac... 161 2e-38
pir||E72739 conserved hypothetical protein APE0447 - Aeropyrum p... 145 6e-34
sp|P49958|YKY5_CAEEL HYPOTHETICAL 45.0 KDA PROTEIN C14B1.5 IN CH... 127 2e-28
gb|AAF50025.1| (AE003544) CG11652 gene product [Drosophila melan... 126 3e-28
dbj|BAB10164.1| (AB016880) gb|AAF50025.1~gene_id:MTG10.5~similar... 120 3e-26
gi|6322088 Yil103wp [Saccharomyces cerevisiae] >gi|731852|sp|P40... 118 1e-25
pir||T40335 hypothetical protein SPBC3B8.05 - fission yeast (Sc... 114 1e-24
gb|AAB36421.1| OVCA1=candidate tumor suppressor [human, fetal br... 106 5e-22
gi|11425095 diptheria toxin resistance protein required for diph... 105 7e-22
gi|4503361 diptheria toxin resistance protein required for dipht... 93 5e-18
>pir||B75092 conserved hypothetical protein PAB0746 - Pyrococcus abyssi (strain
Orsay) >gi|5458551|emb|CAB50039.1| (AJ248286)
OVCA1=CANDIDATE TUMOR SUPPRESSOR related [Pyrococcus
abyssi]
Length = 339
Score = 689 bits (1758), Expect = 0.0
Identities = 339/339 (100%), Positives = 339/339 (100%)
Query: 1 MLHEIPKEEILNELRKLRAKRVLIQSPEGLRKEAEELAEFLEDNGIDAILHGEINYGACD 60
MLHEIPKEEILNELRKLRAKRVLIQSPEGLRKEAEELAEFLEDNGIDAILHGEINYGACD
Sbjct: 1 MLHEIPKEEILNELRKLRAKRVLIQSPEGLRKEAEELAEFLEDNGIDAILHGEINYGACD 60
Query: 61 PADYEAKLLNCDVLIHLGHSYMKLHLEVPTIFVPAFAKVNVVDALKENIDEIRKLGRKII 120
PADYEAKLLNCDVLIHLGHSYMKLHLEVPTIFVPAFAKVNVVDALKENIDEIRKLGRKII
Sbjct: 61 PADYEAKLLNCDVLIHLGHSYMKLHLEVPTIFVPAFAKVNVVDALKENIDEIRKLGRKII 120
Query: 121 LVTTAQHIHQLKEAREFLERMGFLVIIGRGDSRIAWPGQVLGCNYSSAKEDGDGILFIGS 180
LVTTAQHIHQLKEAREFLERMGFLVIIGRGDSRIAWPGQVLGCNYSSAKEDGDGILFIGS
Sbjct: 121 LVTTAQHIHQLKEAREFLERMGFLVIIGRGDSRIAWPGQVLGCNYSSAKEDGDGILFIGS 180
Query: 181 GTFHPLGLAISTKKRVLAINPYSGDFKWIDWERFIRKRWAQIAKAYDARSFGVIVSTKKG 240
GTFHPLGLAISTKKRVLAINPYSGDFKWIDWERFIRKRWAQIAKAYDARSFGVIVSTKKG
Sbjct: 181 GTFHPLGLAISTKKRVLAINPYSGDFKWIDWERFIRKRWAQIAKAYDARSFGVIVSTKKG 240
Query: 241 QLRLAEAKRILKLLREHGRRARLIVMNDVNYYKLEGFPFDAYVVVACPRIALDDYEAWRK 300
QLRLAEAKRILKLLREHGRRARLIVMNDVNYYKLEGFPFDAYVVVACPRIALDDYEAWRK
Sbjct: 241 QLRLAEAKRILKLLREHGRRARLIVMNDVNYYKLEGFPFDAYVVVACPRIALDDYEAWRK 300
Query: 301 PVLTPKEVEILLGLREDYEFDEILGGERSGDEPIGISVH 339
PVLTPKEVEILLGLREDYEFDEILGGERSGDEPIGISVH
Sbjct: 301 PVLTPKEVEILLGLREDYEFDEILGGERSGDEPIGISVH 339
>pir||B71051 conserved hypothetical protein PH1105 - Pyrococcus horikoshii
>gi|3257521|dbj|BAA30204.1| (AP000005) 342aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 342
Score = 564 bits (1439), Expect = e-160
Identities = 274/339 (80%), Positives = 304/339 (88%)
Query: 1 MLHEIPKEEILNELRKLRAKRVLIQSPEGLRKEAEELAEFLEDNGIDAILHGEINYGACD 60
MLHEIPK EIL EL+++ AKRVLIQSPEGLR+EAEELA FLE+N I+ LHGEINYGACD
Sbjct: 1 MLHEIPKSEILKELKRIGAKRVLIQSPEGLRREAEELAGFLEENNIEVFLHGEINYGACD 60
Query: 61 PADYEAKLLNCDVLIHLGHSYMKLHLEVPTIFVPAFAKVNVVDALKENIDEIRKLGRKII 120
PAD EAKL+ CD LIHLGHSYMKL LEVPTIFVPAFA+V+VV+ALKENI EI+KLGRKII
Sbjct: 61 PADREAKLVGCDALIHLGHSYMKLPLEVPTIFVPAFARVSVVEALKENIGEIKKLGRKII 120
Query: 121 LVTTAQHIHQLKEAREFLERMGFLVIIGRGDSRIAWPGQVLGCNYSSAKEDGDGILFIGS 180
+ TTAQHIHQLKEA+EFLE GF V IGRGDSRI+WPGQVLGCNYS AK G+GILFIGS
Sbjct: 121 VTTTAQHIHQLKEAKEFLESEGFEVSIGRGDSRISWPGQVLGCNYSVAKVRGEGILFIGS 180
Query: 181 GTFHPLGLAISTKKRVLAINPYSGDFKWIDWERFIRKRWAQIAKAYDARSFGVIVSTKKG 240
G FHPLGLA++T+K+VLAI+PY+ F WID ERFIRKRWAQIAKA DA+ FGVIVS KKG
Sbjct: 181 GIFHPLGLAVATRKKVLAIDPYTKAFSWIDPERFIRKRWAQIAKAMDAKKFGVIVSIKKG 240
Query: 241 QLRLAEAKRILKLLREHGRRARLIVMNDVNYYKLEGFPFDAYVVVACPRIALDDYEAWRK 300
QLRLAEAKRI+KLL++HGR ARLIVMNDVNY+KLEGFPF+AYVVVACPR+ LDDY AWRK
Sbjct: 241 QLRLAEAKRIVKLLKKHGREARLIVMNDVNYHKLEGFPFEAYVVVACPRVPLDDYGAWRK 300
Query: 301 PVLTPKEVEILLGLREDYEFDEILGGERSGDEPIGISVH 339
PVLTPKEVEILLGLRE+YEFDEILGG R DEP GIS+H
Sbjct: 301 PVLTPKEVEILLGLREEYEFDEILGGPRESDEPFGISIH 339
>gi|11499391 conserved hypothetical protein [Archaeoglobus fulgidus]
>gi|7429972|pir||B69475 conserved hypothetical protein
AF1803 - Archaeoglobus fulgidus
>gi|2648743|gb|AAB89446.1| (AE000978) conserved
hypothetical protein [Archaeoglobus fulgidus]
Length = 310
Score = 238 bits (601), Expect = 7e-62
Identities = 135/321 (42%), Positives = 196/321 (61%), Gaps = 20/321 (6%)
Query: 5 IPKEEILNELRKLRAKRVLIQSPEGLRKEAEELAEFLEDNGIDAILHGEINYGACDPADY 64
IP E++ N AK+V IQ P+GL++ A E+A+ +ED G D ++ GE ++GACD
Sbjct: 6 IPFEKLGN------AKKVGIQLPDGLKRRAIEIAQLIEDRGYDVVISGETSFGACD---I 56
Query: 65 EAKLLNC-DVLIHLGHSYMKLHLEVPTIFVPAFAKVNVVDALKENIDEIRKLGRKIILVT 123
+ +L DVL+H H+ + V ++VP F + N LK +DE R+I L+
Sbjct: 57 DLSILEVVDVLLHFAHTPILKDERV--VYVPYFIEYNPKIDLK--VDE-----RRIALIA 107
Query: 124 TAQHIHQLKEAREFLERMGFLVIIGRGDSRIAWPGQVLGCNYSSAK-EDGDGILFIGSGT 182
TAQ++H+L E E+L G+ V IG R+ +PGQVLGCNYS + + D ++FIG G
Sbjct: 108 TAQYVHKLPEVAEWLRGKGYEVEIGSPRGRVVYPGQVLGCNYSVLRGSNADAVVFIGDGL 167
Query: 183 FHPLGLAISTKKRVLAINPYSGDFKWIDWERFIRKRWAQIAKAYDARSFGVIVSTKKGQL 242
FH G A+ TKK+V A NP SG+ K +D F +KR+ +++K G++VS+K GQ
Sbjct: 168 FHATGAAMYTKKKVYAYNPLSGELKEVDARNFEKKRYLEVSKCVGKSKAGILVSSKPGQR 227
Query: 243 RLAEAKRILKLLREHGRRARLIVMNDVNYYKLEGFPFDAYVVVACPRIALDDYEAWRKPV 302
RL A+++ K+ RE+G +I +N+V +L PFD YV ACPRIA DD + KPV
Sbjct: 228 RLRLAEKLKKIGRENGLFCSIIYLNNVRAEELYNLPFDFYVNTACPRIAYDDGARFEKPV 287
Query: 303 LTPKEVEILLGLREDYEFDEI 323
++P+E E+LLGLRE DEI
Sbjct: 288 ISPQEFELLLGLRESIAMDEI 308
>pir||C69042 conserved hypothetical protein MTH1319 - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2622425|gb|AAB85797.1| (AE000896) conserved protein
[Methanobacterium thermoautotrophicum]
Length = 330
Score = 238 bits (601), Expect = 7e-62
Identities = 135/332 (40%), Positives = 209/332 (62%), Gaps = 11/332 (3%)
Query: 2 LHEIPKEEILNELRKLRAKRVLIQSPEGLRKEAEELAEFLE-DNGIDAILHGEINYGACD 60
L+ + E ++ E+RK A V +Q PEGL+ A ELAE +E + G A++ + +GACD
Sbjct: 3 LYRLETERVIGEIRKRNAGVVGLQFPEGLKMRAVELAEQIESETGATAVISADPCFGACD 62
Query: 61 PADYEAKLLNCDVLIHLGHSYMKLHLEVPTIFVPAFAKVNVVDALKENIDEIRKLGRKII 120
+D + + + D+++H GH+ + L EVP IF+ A + V V + ++E D + R+I
Sbjct: 63 VSDRKMRDM-VDLIVHYGHTPLPLDYEVPVIFIEAASSVEVGEVIREAADRLSG-HRRIG 120
Query: 121 LVTTAQHIHQLKEAREFLERMGFLVIIGRGDSRIAWPGQVLGCNYSSAK-EDGDGILFIG 179
+ TTAQH+H L +AR LE GF V+ G G + GQVLGCN+S+ + D D LF+G
Sbjct: 121 IATTAQHLHLLDQARSLLEERGFEVVTGEGVNTAR--GQVLGCNFSAIRGTDADAYLFLG 178
Query: 180 SGTFHPLGLAISTKKRVLAINPYSGDFKWIDW--ERFIRKRWAQIAKAYDARSFGVIVST 237
SG FHPLG+ + T + V+ +PY G+ + I+ +R +R R+A+I++A DA +GV+VS+
Sbjct: 179 SGNFHPLGIKLFTGREVVVADPYHGEVRDIEEFADRVLRVRFARISRASDASRWGVVVSS 238
Query: 238 KKGQLRLAEAKRILKLLREHGRRARLIVMNDVNYYKLEGF-PFDAYVVVACPRIALDDYE 296
K GQ+R A + K L E GR A +++ +++ L F +A+VV ACPRIA+DD +
Sbjct: 239 KAGQMRFELALMVKKKLEEAGREALILLAENISPAALLPFRELEAFVVTACPRIAIDDSQ 298
Query: 297 AWRKPVLTPKEVEILLGLR--EDYEFDEILGG 326
+ +P+L P E+EI+LG R +DY DEI+ G
Sbjct: 299 LYDRPLLNPSELEIVLGERSWDDYTLDEIIHG 330
>gb|AAG19302.1| (AE005026) Vng0854c [Halobacterium sp. NRC-1]
Length = 344
Score = 213 bits (537), Expect = 2e-54
Identities = 132/325 (40%), Positives = 191/325 (58%), Gaps = 19/325 (5%)
Query: 8 EEILNELRKLRAKRVLIQSPEGLRKE----AEELAEFLEDNGIDAILHGEINYGACDPAD 63
+ I++E+ + A++V +Q PEGL++ A++L L+D I +L G+ YGACD
Sbjct: 30 DRIVDEVERKDAEKVGLQFPEGLKRRGPAVADDLRARLDDTRI--MLSGQPCYGACDLDT 87
Query: 64 YEAKLLNCDVLIHLGHSYMKLHLEVPTIFVPAFAKVNVVDALKENIDEIRKLGRKIILVT 123
Y + DV +H GHS MK + I+VP F+ V+V ++E DE+ + LVT
Sbjct: 88 YLMR--RTDVFVHFGHSPMKESDSI--IYVPLFSNVDVEPIMQEARDELHD--GDVGLVT 141
Query: 124 TAQHIHQLKEAREFLERMGFLVIIGRGDSRIAWPGQVLGCNYSSAKEDGDGILFIGSGTF 183
TAQH++Q +E R +LE G+ V RGD R+ GQVLGCNY+SA D D +L++G G F
Sbjct: 142 TAQHMNQFEEMRTWLEERGYTVHTRRGDDRLTNEGQVLGCNYASADIDADQVLYVGGGKF 201
Query: 184 HPLGLAIS-TKKRVLAINPYSGDFKWIDWERFIRKRWAQIAKAYDARSFGVIVSTKKGQL 242
HPLGLA+ +K V+ +P + D E+F+++R+A + KA DA +GVI TK GQ
Sbjct: 202 HPLGLAMEHPEKNVVIADPVNNAVSIADAEQFLKERYASVHKAMDAEQWGVIFCTKIGQG 261
Query: 243 RLAEAKRILKLLREHGRRARLIVMNDVNYYKLEGFPFDAYVVVACPRIALDDYEAWRKPV 302
R +A+ I+ E+ A LI M++V +L F DA+V CPRI DD + KP+
Sbjct: 262 RFDQAEEIV----ENNDNAYLITMDEVTPDRLMNFDMDAFVNTGCPRITTDDGPQFHKPM 317
Query: 303 LTPKEVEILLGLR--EDYEFDEILG 325
LTP E EI +G + ED FD G
Sbjct: 318 LTPGEYEIAVGNKPLEDLSFDTFHG 342
>gb|AAK40633.1| Conserved hypothetical protein [Sulfolobus solfataricus]
Length = 333
Score = 185 bits (465), Expect = 6e-46
Identities = 108/322 (33%), Positives = 183/322 (56%), Gaps = 10/322 (3%)
Query: 1 MLHEIPKEEILNELRKLRAKRVLIQSPEGLRKEAEELAEFLEDN--GIDAILHGEINYGA 58
M + +E ++ E+R+ AKRVL+Q PEGL+ + ++ + L + ++ I+ GE ++GA
Sbjct: 1 MSYNFEEERVIKEIREKNAKRVLLQFPEGLKYFSIDIVKKLREKLPNVNFIISGEPSWGA 60
Query: 59 CDPADYEAKLLNCDVLIHLGHS-YMKLHLEVPTIFVPAFAKVNVVD-ALKENIDEIRKL- 115
CD A+ EA+ +N D++IH GH+ Y + + PTIF+ A + +++ + AL ++I K
Sbjct: 61 CDIAEDEAQQVNADLIIHFGHTPYTWYYPKFPTIFINAESNLDISENALHSLENDISKYN 120
Query: 116 GRKIILVTTAQHIHQLKEAREFLERMGFLVIIGRGDSRIAWPGQVLGCNYSSAKEDGDGI 175
GRKI L T QH+ L + + FLE G+ ++IG+ +R + GQVLGC+Y +A+ + D
Sbjct: 121 GRKISLTATLQHVRLLSKIKSFLEDKGYDIVIGKPSNRFMFDGQVLGCDYKAAEVEADIY 180
Query: 176 LFIGSGTFHPLGLAISTKKRVLAINPYSGDFKWI--DWERFIRKRWAQIAKAYDARSFGV 233
+ + G FH LGL ++T K + ++PY + I D + ++ R+ +I +A D RS+ +
Sbjct: 181 VIVSGGLFHALGLGLATNKPTIKLDPYLQKSEDITNDVRKILKVRYGKILQALDKRSWVI 240
Query: 234 IVSTKKGQLRLAEAKRILKLLREHGRRARLIVMNDVNYYKLEGFP---FDAYVVVACPRI 290
I K GQ R K L E G + + L D ++V +CPR+
Sbjct: 241 IQGVKVGQNRPNMIKYFYDKLTEKGYDVFTVTNKVLTLDILRNLDRNYIDVFLVTSCPRL 300
Query: 291 ALDDYEAWRKPVLTPKEVEILL 312
+DD + KPVLTP E ++++
Sbjct: 301 PIDDLYNYEKPVLTPGEAKMII 322
>sp|Q57907|Y483_METJA HYPOTHETICAL PROTEIN MJ0483 >gi|2128012|pir||C64360 conserved
hypothetical protein MJ0483 - Methanococcus jannaschii
>gi|1591186|gb|AAB98474.1| (U67498) conserved
hypothetical protein [Methanococcus jannaschii]
Length = 340
Score = 168 bits (422), Expect = 7e-41
Identities = 113/342 (33%), Positives = 179/342 (52%), Gaps = 44/342 (12%)
Query: 2 LHEIPKEEILNELRKLRAK--RVLIQSPEGLR----KEAEELAEFLEDNGI--DAILHGE 53
L + E ++ E+ L +V+ Q+PEGL+ KE E++ ++ + I + L G
Sbjct: 18 LFNLETERVIREIENLNKNNPKVIFQAPEGLKLKVEKEIEKIKQYFKQKNINIEIYLWGN 77
Query: 54 INYGACDPADYEAKLLNCDVLIHLGHSYMKL-HLEVPTIFVPAFAKVN------VVDALK 106
+GACD D K LN D++IH GH + + E+ T+F+PA+ N +++ +K
Sbjct: 78 TCFGACDLIDNHVKNLNVDLIIHYGHEKLSYANPEIKTLFIPAYHIFNKDEEEKILNDIK 137
Query: 107 ENIDEIRKLGRKIILVTTAQHIHQLKEAREFLERMGFLVIIGRGDSRIAWPGQVLGCNYS 166
I++ + G+K+ + TT Q+ LK+ P +LGC
Sbjct: 138 NFIEKHKSGGKKVAIATTIQYKKLLKDFN---------------------PSIILGCR-- 174
Query: 167 SAKEDGDGILFIGSGTFHPLGLAISTKKRVLAINPYSGDFKWIDWE---RFIRKRWAQIA 223
++GD ILF+G+G FHPL +A +K V NP S F I E +FI+KR I+
Sbjct: 175 GEVKEGDVILFVGTGRFHPLMIAYKYQKEVFIYNPLSKCFDKISEEEINKFIKKRILAIS 234
Query: 224 KAY--DARSFGVIVSTKKGQLRLAEAKRILKLLREHGRRARLIVMNDVNYYKLEGFPFDA 281
K + GV++STKKGQ R I+KLL E+ I++++++ L + D
Sbjct: 235 KLLLNKPKKVGVVLSTKKGQCRKRVFDEIIKLLEENDVNYLPILVDNISPDILF-YDVDC 293
Query: 282 YVVVACPRIALDDYEAWRKPVLTPKEVEILLGLREDYEFDEI 323
Y++VACPRI LDDY ++KP+ TP+E ++ L Y+FDEI
Sbjct: 294 YIIVACPRIVLDDYILYKKPIYTPEEFKLFLKNSFKYKFDEI 335
>emb|CAC11400.1| (AL445063) hypothetical protein [Thermoplasma acidophilum]
Length = 349
Score = 161 bits (402), Expect = 2e-38
Identities = 106/334 (31%), Positives = 176/334 (51%), Gaps = 17/334 (5%)
Query: 8 EEILNELRKLRAKRVLIQSPEGLRKEAEELAEFLEDNGIDAILHGEINYGACD--PADYE 65
EE LR++ A+++L+Q P+GL+ A + +L D IL YGACD P+
Sbjct: 24 EEADRRLREIGARKILLQLPDGLKPYAFDYFTYLSQR-YDVILSSSPVYGACDIGPSYLY 82
Query: 66 AKLLNCDVLIHLGHSYMK-LHLEVPTIFVPAFAKVNVVDALKENIDEIRKLGRKIILVTT 124
++ D ++ +GHS M+ + P IF+ + V+V D E + R++G L+ +
Sbjct: 83 DRV---DAIVQVGHSIMRNVKYPRPVIFIEHYRTVDVEDINTEALKNYRRIG----LIYS 135
Query: 125 AQHIHQLKEAREFLERMGFLVIIGRGDSRIAWPGQVLGCNYSSA---KEDGDGILFIGSG 181
Q+ + LE GF VIIGR D R+ + GQVLGCN+SS + + + + + +G
Sbjct: 136 IQYRPVADRVKRILESKGFEVIIGRSDRRMTYDGQVLGCNFSSVHSVEAEVEAFVIVSTG 195
Query: 182 TFHPLGLAISTKKRVLAINPYSGDFKWIDWER--FIRKRWAQIAKAYDARSFGVIVSTKK 239
+FH LG IST++ V ++ + ++ E FIRKR+AQI +A DA+ +V T+
Sbjct: 196 SFHALGSQISTERPVFLLDLNEMSLRSMEKEADTFIRKRYAQIYRAMDAKRICFLVDTRI 255
Query: 240 GQLRLAEAKRILKLLREHGRRARLIVMNDVNYYKLEGFPFDAYVVVACPRIALDDYEAWR 299
GQ R A+ ++ R+ G+ A L ++++ ++ D V CPR+ +DD + +
Sbjct: 256 GQRREKLARMLMDRARDLGKEAVLAYTDNISDQDIQNMGCDLAVYTGCPRVPIDDQDRFT 315
Query: 300 KPVLTPKEVEI-LLGLREDYEFDEILGGERSGDE 332
PVLTP E + + Y DEI+ + D+
Sbjct: 316 VPVLTPAEFSMAFFKSSKRYVLDEIVSVDEFTDQ 349
>pir||E72739 conserved hypothetical protein APE0447 - Aeropyrum pernix (strain
K1) >gi|5104093|dbj|BAA79409.1| (AP000059) 340aa long
hypothetical protein [Aeropyrum pernix]
Length = 340
Score = 145 bits (363), Expect = 6e-34
Identities = 101/327 (30%), Positives = 168/327 (50%), Gaps = 21/327 (6%)
Query: 15 RKLRAKRVLIQSPEGLRKEAEELAEFLED---NGIDAILHGEINYGACDPADYEAKL-LN 70
R+ A+R+++Q PEG+ + +A+ E+ LH + +GACD E +
Sbjct: 12 RRRGARRIVLQLPEGMLQYGLYIAKCFEEMLGGAAQVYLHADPTFGACDLHYGELDTTVR 71
Query: 71 CDVLIHLGHS-------YMKLHLEVPTIFVPAFAKVNV-VDALKENIDEI--RKLGRKII 120
D+++H+GHS + L ++V A +K + +DAL+E + R R++
Sbjct: 72 PDLIVHVGHSPYPAELAHEGLEPRGRVVYVRALSKSQLPLDALREAAGLLASRYGVRRVG 131
Query: 121 LVTTAQHIHQLKEAREFLERMGFLVIIGRGDSRIAWPGQVLGCNYSSAKE-DGDGILFIG 179
+ TTAQH H ++A E L G V + G QVLGC+Y A+ DG +++G
Sbjct: 132 IATTAQHTHLAEKAAEVLRGEGLEVAVPPGLRPYFGAAQVLGCDYRLARGVRADGFVYVG 191
Query: 180 SGTFHPLGLAISTKKRVLAINPYSGDFKWI--DWERFIRKRWAQIAKAYDARSFGVIVST 237
G FHPLGL ++T K V+ ++PY G + + + E+ R R +++++ AR +G+IV
Sbjct: 192 GGVFHPLGLYLATLKPVVQVDPYRGVSEDLTREGEKLYRSRLYRVSQSIGARRWGIIVGL 251
Query: 238 KKGQLRLAEAKRILKLLREHGRRARLIVMNDVNYYKLEGFP---FDAYVVVACPRIALDD 294
K GQ R +++ + + G L+ +L F+A+ V +CPR+ DD
Sbjct: 252 KSGQYRPWLVEKLARAIESAGGEYLLVASEVTTLSQLVAIDNPWFEAFTVTSCPRLPTDD 311
Query: 295 YEAWRKPVLTPKEVEILL-GLREDYEF 320
+ ++ KPVLTP E + L G E Y F
Sbjct: 312 FWSYEKPVLTPGEAMMALEGRLEPYRF 338
>sp|P49958|YKY5_CAEEL HYPOTHETICAL 45.0 KDA PROTEIN C14B1.5 IN CHROMOSOME III
>gi|7495975|pir||T19272 hypothetical protein C14B1.5 -
Caenorhabditis elegans >gi|3874296|emb|CAA85493.1|
(Z37139) contains similarity to Pfam domain: PF01866
(Putative diphthamide synthesis protein), Score=651.6,
E-value=1.3e-192, N=1~cDNA EST yk376a7.5 comes from this
gene~cDNA EST yk463e3.3 comes from this gene~cDNA EST
yk340h11.5 comes from this gene~c>
Length = 396
Score = 127 bits (315), Expect = 2e-28
Identities = 95/324 (29%), Positives = 161/324 (49%), Gaps = 25/324 (7%)
Query: 4 EIPKEEILNELRKLRAKRVLIQSPEGLRKEAEELAEFLED-NGIDAILHGEINYGACDPA 62
E+PK + ++R +K V +Q PEGL A +A+ LE G D ++ G++ YGAC
Sbjct: 35 EVPKT--IWKIRSTESKYVALQFPEGLIMYACVIADILEKYTGCDTVIMGDVTYGACCVD 92
Query: 63 DYEAKLLNCDVLIHLGHSYMKLHLEVPTIFVPAFAKVNV-------VDALKENIDEIRKL 115
DY AK + CD+L+H GHS + + ++ + VN+ +D +KEN
Sbjct: 93 DYTAKSMGCDLLVHYGHSCL-VPIQNTDGIAMLYVFVNIHINLSHLIDCVKENFQ----- 146
Query: 116 GRKIILVTTAQHIHQLKEAREFLERMGFLVIIGRGDSRIAWPGQVLGCNYSSAKEDG--- 172
G+++++V+T Q I L+ R + + I + PG+VLGC +S + D
Sbjct: 147 GKRLVVVSTVQFIPSLQTLRTTFNKDDSSIRIDIPQCKPLSPGEVLGC--TSPRLDASKY 204
Query: 173 DGILFIGSGTFHPLGLAISTKK-RVLAINPYSGDF--KWIDWERFIRKRWAQIAKAYDAR 229
D I+++G G FH + I + +PYS ++ D + + R I A
Sbjct: 205 DAIVYLGDGRFHLESIMIHNPEIEAFQYDPYSRKLTREFYDHDLMRKNRIGSIEIARKCT 264
Query: 230 SFGVIVSTKKGQLRLAEAKRILKLLREHGRRARLIVMNDVNYYKLEGFP-FDAYVVVACP 288
+FG+I T Q L + + L G++ ++++++ KL FP D +V VACP
Sbjct: 265 TFGLIQGTLGRQGNLKVVEELEAQLERKGKKFLRVLLSEIFPEKLAMFPEVDCWVQVACP 324
Query: 289 RIALDDYEAWRKPVLTPKEVEILL 312
R+++D + KP+L P E+ + L
Sbjct: 325 RLSIDWGTQFPKPLLYPFELAVAL 348
>gb|AAF50025.1| (AE003544) CG11652 gene product [Drosophila melanogaster]
Length = 454
Score = 126 bits (314), Expect = 3e-28
Identities = 93/311 (29%), Positives = 158/311 (49%), Gaps = 16/311 (5%)
Query: 14 LRKLRAKRVLIQSPEGLRKEAEELAEFLED-NGIDAILHGEINYGACDPADYEAKLLNCD 72
+R+++AKRV +Q PEGL A +++ +E D ++ G++ YGAC DY AK L D
Sbjct: 71 IREMKAKRVALQLPEGLLMYAMVISDIVERFTSADTVIMGDVTYGACCVDDYTAKALGAD 130
Query: 73 VLIHLGHSYM-----KLHLEVPTIFVP-AFAKVNVVDALKENIDEIRKLGRKIILVTTAQ 126
+L+H GHS + ++V IFV ++ +D++K N R +I LV+T Q
Sbjct: 131 LLVHYGHSCLIPVDQTCGIKVLYIFVDIKIDPLHFLDSVKLN---FRPEVGQIALVSTIQ 187
Query: 127 HIHQLKEAREFLERMGFLVIIGRGDSRIAWPGQVLGCNYSSAKEDGDGILFIGSGTFHPL 186
+ L+ A L+ G+ VI+ + ++ PG++LGC E I+++G G FH
Sbjct: 188 FVTTLQAASTELKAAGYDVIVPQ--AKPLSPGEILGCTSPQLPETTKMIIYLGDGRFHLE 245
Query: 187 GLAISTK-KRVLAINPYSGDF--KWIDWERFIRKRWAQIAKAYDARSFGVIVSTKKGQLR 243
I+ + +PY F + D R + +A AR G+I+ T Q
Sbjct: 246 SAMIANPLLKAYKYDPYEKKFTTEQYDHSAMQNLRLDAVQRAKKARRIGIILGTLGRQGS 305
Query: 244 LAEAKRILKLLREHGRRARLIVMNDVNYYKLEGF-PFDAYVVVACPRIALDDYEAWRKPV 302
+ + K L G ++++++ KL F DA+V +ACPR+++D A+ +P+
Sbjct: 306 SRVHRFLEKRLHAKGIETTTLLLSEIFPQKLALFADIDAFVQIACPRLSIDWGSAFSQPL 365
Query: 303 LTPKEVEILLG 313
L P E+ ++LG
Sbjct: 366 LNPYELSVVLG 376
>dbj|BAB10164.1| (AB016880) gb|AAF50025.1~gene_id:MTG10.5~similar to unknown protein
[Arabidopsis thaliana]
Length = 468
Score = 120 bits (297), Expect = 3e-26
Identities = 91/313 (29%), Positives = 155/313 (49%), Gaps = 15/313 (4%)
Query: 14 LRKLRAKRVLIQSPEGLRKEAEELAEFLED--NGIDAILHGEINYGACDPADYEAKLLNC 71
++ AKR+ +Q PEGL A L++ + G++ YGAC D+ A L
Sbjct: 73 IKTSNAKRIALQLPEGLLMYALTLSDIFTSFAGASHCFVLGDVTYGACCVDDFSACALGA 132
Query: 72 DVLIHLGHSYMKL--HLEVPTIFVPAFAKVNVVDALKENIDEIRKLGRKIILVTTAQHIH 129
D+LIH GHS + ++P ++V +++V L + + IIL T Q
Sbjct: 133 DLLIHYGHSCLVPIDSTKIPCLYVFVEIQIDVKCLLNTIHLNLASDVKNIILAGTIQFTS 192
Query: 130 QLKEAREFLERMGFLVIIGRGDSRIAWPGQVLGCNYSSAKEDGDG----ILFIGSGTFHP 185
++ + LE+ GF V+I + A G+VLGC K D ++F+ G FH
Sbjct: 193 AIRAVKPELEKQGFNVLIPQSKPLSA--GEVLGCTAPKVKTVEDCKDQVLVFVADGRFHL 250
Query: 186 LGLAISTKK-RVLAINPYSGDF--KWIDWERFIRKRWAQIAKAYDARSFGVIVSTKKGQL 242
I+ K + +PY G + D + R IA+A +A+++G+++ T Q
Sbjct: 251 EAFMIANPKIKAFRYDPYLGKLFLEEYDHKGMRETRMRAIARAREAKTWGIVLGTLGRQG 310
Query: 243 RLAEAKRILKLLREHGRRARLIVMNDVNYYKLEGFP--FDAYVVVACPRIALDDYEAWRK 300
+R+ K + E G + +++M++++ ++ F DA+V +ACPR+++D EA+ K
Sbjct: 311 NPKILERLEKKMMEKGIDSTVVLMSELSPTRVALFEDSVDAWVQIACPRLSIDWGEAFLK 370
Query: 301 PVLTPKEVEILLG 313
P+LT E EI LG
Sbjct: 371 PLLTTFEAEIALG 383
>gi|6322088 Yil103wp [Saccharomyces cerevisiae] >gi|731852|sp|P40487|YIK3_YEAST
HYPOTHETICAL 48.3 KDA PROTEIN IN MOB1-SGA1 INTERGENIC
REGION >gi|626372|pir||S48469 probable membrane protein
YIL103w - yeast (Saccharomyces cerevisiae)
>gi|558703|emb|CAA86277.1| (Z38125) orf, len: 425, CAI:
0.19 [Saccharomyces cerevisiae]
Length = 425
Score = 118 bits (292), Expect = 1e-25
Identities = 95/320 (29%), Positives = 161/320 (49%), Gaps = 16/320 (5%)
Query: 14 LRKLRAKRVLIQSPEGLRKEAEELAEFLEDN-GIDAILHGEINYGACDPADYEAKLLNCD 72
+RK AKR+ +Q PEGL + +++ LE G++ ++ G+++YGAC D+ A+ L+CD
Sbjct: 87 IRKYNAKRIALQMPEGLLIYSLIISDILEQFCGVETLVMGDVSYGACCIDDFTARALDCD 146
Query: 73 VLIHLGHSYMKLHLEVPTIFV-PAFAKVNV-VDALKENIDEIRKLGRKIILVTTAQH--- 127
++H HS + + ++V I V F +N+ D + + + + G +I T Q
Sbjct: 147 FIVHYAHSCL-VPIDVTKIKVLYVFVTINIQEDHIIKTLQKNFPKGSRIATFGTIQFNPA 205
Query: 128 IHQLKEAREFLERMGFLVIIGRGDSRIAWPGQVLGCNYSSA-KEDGDGILFIGSGTFHPL 186
+H +++ + L ++ I + G+VLGC KE D ++FIG G FH
Sbjct: 206 VHSVRD--KLLNDEEHMLYIIPPQIKPLSRGEVLGCTSERLDKEQYDAMVFIGDGRFHLE 263
Query: 187 GLAISTKK-RVLAINPYSGDF--KWIDWERFIRKRWAQIAKAYDARSFGVIVSTKKGQLR 243
I + +PY+ F + D ++ + R I A + FG+I+ Q
Sbjct: 264 SAMIHNPEIPAFKYDPYNRKFTREGYDQKQLVEVRAEAIEVARKGKVFGLILGALGRQGN 323
Query: 244 LAEAKRILKLLREHGRRARLIVMNDVNYYKLEGF-PFDAYVVVACPRIALDDYEAWRKPV 302
L K + K L G+ I++++V KL F D +V VACPR+++D A+ KP+
Sbjct: 324 LNTVKNLEKNLIAAGKTVVKIILSEVFPQKLAMFDQIDVFVQVACPRLSIDWGYAFNKPL 383
Query: 303 LTPKEVEILLGLREDYEFDE 322
LTP E +L L++D F E
Sbjct: 384 LTPYEASVL--LKKDVMFSE 401
>pir||T40335 hypothetical protein SPBC3B8.05 - fission yeast
(Schizosaccharomyces pombe) >gi|2995340|emb|CAA18294.1|
(AL022244) hypothetical protein [Schizosaccharomyces
pombe]
Length = 436
Score = 114 bits (283), Expect = 1e-24
Identities = 95/329 (28%), Positives = 160/329 (47%), Gaps = 28/329 (8%)
Query: 14 LRKLRAKRVLIQSPEGLRKEAEELAEFLEDN-GIDAILHGEINYGACDPADYEAKLLNCD 72
+R +AKRV +Q PEGL L++ E ++ I+ G++ YGAC D+ A+ L+CD
Sbjct: 84 IRLRKAKRVALQLPEGLLMFGCILSDIFEQFCQVETIVMGDVTYGACCIDDFTARALDCD 143
Query: 73 VLIHLGHSYMKLHLEVPTIFVPAFAKV-----NVVDALKENIDEIRKLGRKIILVTTAQH 127
L+H GHS + + P + F + +VV +LK N+ ++ LV T Q
Sbjct: 144 FLVHYGHSCLIPVDQTPIKVLYVFVDIKIDLQHVVSSLKHNLPS----NSRLALVGTIQF 199
Query: 128 IHQLKEAREFLE------RMGFLVIIGRGDSRIAWPGQVLGCNYSSAKEDG--DGILFIG 179
+ L ++ L+ + GF V+I + ++ PG+ LGC S E G D +++IG
Sbjct: 200 VGSLNSIKDALQIQDEDGKGGFYVVIPQ--AKPLSPGEALGCT-SPYIEKGSVDALIYIG 256
Query: 180 SGTFHPLGLAISTKK-RVLAINPYSGDFKWIDW--ERFIRKRWAQIAKAYDARSFGVIVS 236
G FH + I+ +PYS + E R++ + KA A+ FG+I
Sbjct: 257 DGRFHLESVMIANPDLPAYRYDPYSHKLSIESYAHEEMKSIRYSAVEKARTAKKFGLIQG 316
Query: 237 TKKGQLRLAEAKRILKLLREHGRRARLIVMNDVNYYKLEGF-PFDAYVVVACPRIALDDY 295
T Q + + LR++ + ++M+++ +L F DA++ VACPR+++D
Sbjct: 317 TLGRQGSPKVLENLKNTLRKNNKDFVCVLMSEIFPSRLGQFSDIDAWIQVACPRLSIDWG 376
Query: 296 EAWRKPVLTPKEVEILLGL---REDYEFD 321
A+ P+LTP E + +E Y D
Sbjct: 377 YAFPAPLLTPYEASAAFNVVPWKEVYPMD 405
>gb|AAB36421.1| OVCA1=candidate tumor suppressor [human, fetal brain, Peptide, 443
aa]
Length = 443
Score = 106 bits (261), Expect = 5e-22
Identities = 89/319 (27%), Positives = 157/319 (48%), Gaps = 17/319 (5%)
Query: 4 EIPKEEILNELRKLRAKRVLIQSPEGLRKEAEELAEFLED-NGIDAILHGEINYGACDPA 62
EIPK + +++ +AK+V +Q PEGL A + + LE + ++ G++ YGAC
Sbjct: 61 EIPKT--IWRIQQAQAKKVALQMPEGLLLFACTIVDILERFTEAEVMVMGDVTYGACCVD 118
Query: 63 DYEAKLLNCDVLIHLGHSYMKLHLEVPTIFVPAFAKVNVVDALKENIDEIRKL---GRKI 119
D+ A+ L D L+H GHS + F + V++ +D +R +
Sbjct: 119 DFTARALGADFLVHYGHSCLMPMDTSAQDFRVLYVFVDIRIDTTHLLDSLRLTFPPATAL 178
Query: 120 ILVTTAQHIHQLKEAREFLERMGFLVIIGRGDSRIAWPGQVLGCNYSSAKEDGDGILFIG 179
LV+T Q + L+ A + L + + V + + + PG++LGC + + ++++G
Sbjct: 179 ALVSTIQFVSTLQAAAQEL-KAEYRVSVPQ--CKPLSPGEILGCTSPRLSREVEAVVYLG 235
Query: 180 SGTFHPLGLAISTKK-RVLAINPYSG--DFKWIDWERFIRKRWAQIAKAYDARSFGVIVS 236
G FH + I+ +PYS + D +R R IA A A+S+G+I+
Sbjct: 236 DGRFHLESVMIANPNVPAYRYDPYSKVLSREHYDHQRMQAARQEAIATARSAKSWGLILG 295
Query: 237 T--KKGQLRLAEAKRILKLLREHGRRARLIVMNDVNYYKLEGFP-FDAYVVVACPRIALD 293
T ++G ++ E + LR G ++++++ KL P D +V VACPR+++D
Sbjct: 296 TLGRQGSPKILE--HLESRLRALGLSFVRLLLSEIFPSKLSLLPEVDVWVQVACPRLSID 353
Query: 294 DYEAWRKPVLTPKEVEILL 312
A+ KP+LTP E + L
Sbjct: 354 WGTAFPKPLLTPYEAAVAL 372
>gi|11425095 diptheria toxin resistance protein required for diphthamide
biosynthesis (Saccharomyces)-like 1 [Homo sapiens]
Length = 420
Score = 105 bits (260), Expect = 7e-22
Identities = 89/319 (27%), Positives = 158/319 (48%), Gaps = 17/319 (5%)
Query: 4 EIPKEEILNELRKLRAKRVLIQSPEGLRKEAEELAEFLED-NGIDAILHGEINYGACDPA 62
EIPK + +++ +AK+V +Q PEGL A + + LE + ++ G++ YGAC
Sbjct: 38 EIPKT--IWRIQQAQAKKVALQMPEGLLLFACTIVDILERFTEAEVMVMGDVTYGACCVD 95
Query: 63 DYEAKLLNCDVLIHLGHSYMKLHLEVPTIFVPAFAKVNVVDALKENIDEIRKL---GRKI 119
D+ A+ L D L+H GHS + F + V++ +D +R +
Sbjct: 96 DFTARALGADFLVHYGHSCLIPMDTSAQDFRVLYVFVDIRIDTTHLLDSLRLTFPPATAL 155
Query: 120 ILVTTAQHIHQLKEAREFLERMGFLVIIGRGDSRIAWPGQVLGCNYSSAKEDGDGILFIG 179
LV+T Q + L+ A + L + + V + + + PG++LGC ++ + ++++G
Sbjct: 156 ALVSTIQFVSTLQAAAQEL-KAEYRVSVPQ--CKPLSPGEILGCTSPRLSKEVEAVVYLG 212
Query: 180 SGTFHPLGLAISTKK-RVLAINPYSG--DFKWIDWERFIRKRWAQIAKAYDARSFGVIVS 236
G FH + I+ +PYS + D +R R IA A A+S+G+I+
Sbjct: 213 DGRFHLESVMIANPNVPAYRYDPYSKVLSREHYDHQRMQAARQEAIATARSAKSWGLILG 272
Query: 237 T--KKGQLRLAEAKRILKLLREHGRRARLIVMNDVNYYKLEGFP-FDAYVVVACPRIALD 293
T ++G ++ E + LR G ++++++ KL P D +V VACPR+++D
Sbjct: 273 TLGRQGSPKILE--HLESRLRALGLSFVRLLLSEIFPSKLSLLPEVDVWVQVACPRLSID 330
Query: 294 DYEAWRKPVLTPKEVEILL 312
A+ KP+LTP E + L
Sbjct: 331 WGTAFPKPLLTPYEAAVAL 349
>gi|4503361 diptheria toxin resistance protein required for diphthamide
biosynthesis (Saccharomyces)-like 1; diptheria toxin
resistance protein required for diphthamide biosynthesis
(Saccharomyces)-like [Homo sapiens]
>gi|1438781|gb|AAB36297.1| (S81752) DPH2L=candidate
tumor suppressor gene {ovarian cancer critical region of
deletion} [human, 9 week fetal and placental tissues,
Peptide, 363 aa] [Homo sapiens]
>gi|1490415|gb|AAD10198.1| (U34880) DPH2L [Homo sapiens]
Length = 363
Score = 92.8 bits (227), Expect = 5e-18
Identities = 81/296 (27%), Positives = 142/296 (47%), Gaps = 15/296 (5%)
Query: 27 PEGLRKEAEELAEFLED-NGIDAILHGEINYGACDPADYEAKLLNCDVLIHLGHSYMKLH 85
PEGL A + + LE + ++ G++ YGAC D+ A+ L D L+H GHS +
Sbjct: 2 PEGLLLFACTIVDILERFTEAEVMVMGDVTYGACCVDDFTARALGADFLVHYGHSCLIPM 61
Query: 86 LEVPTIFVPAFAKVNVVDALKENIDEIRKL---GRKIILVTTAQHIHQLKEAREFLERMG 142
F + V++ +D +R + LV+T Q + L+ A + L +
Sbjct: 62 DTSAQDFRVLYVFVDIRIDTTHLLDSLRLTFPPATALALVSTIQFVSTLQAAAQEL-KAE 120
Query: 143 FLVIIGRGDSRIAWPGQVLGCNYSSAKEDGDGILFIGSGTFHPLGLAISTKK-RVLAINP 201
+ V + + + PG++LGC ++ + ++++G G FH + I+ +P
Sbjct: 121 YRVSVPQ--CKPLSPGEILGCTSPRLSKEVEAVVYLGDGRFHLESVMIANPNVPAYRYDP 178
Query: 202 YSG--DFKWIDWERFIRKRWAQIAKAYDARSFGVIVST--KKGQLRLAEAKRILKLLREH 257
YS + D +R R IA A A+S+G+I+ T ++G ++ E + LR
Sbjct: 179 YSKVLSREHYDHQRMQAARQEAIATARSAKSWGLILGTLGRQGSPKILE--HLESRLRAL 236
Query: 258 GRRARLIVMNDVNYYKLEGFP-FDAYVVVACPRIALDDYEAWRKPVLTPKEVEILL 312
G ++++++ KL P D +V VACPR+++D A KP+LTP E + L
Sbjct: 237 GLSFVRLLLSEIFPSKLSLLPEVDVWVQVACPRLSIDWGTASPKPLLTPYEAAVAL 292
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.322 0.142 0.424
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 129612979
Number of Sequences: 2977
Number of extensions: 5677081
Number of successful extensions: 14174
Number of sequences better than 1.0e-10: 17
Number of HSP's better than 0.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 14118
Number of HSP's gapped (non-prelim): 17
length of query: 339
length of database: 189,106,746
effective HSP length: 53
effective length of query: 286
effective length of database: 157,386,935
effective search space: 45012663410
effective search space used: 45012663410
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.9 bits)
S2: 165 (68.7 bits)