BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0754 (PAB0754) DE:MACROLIDE-EFFLUX DETERMINANT related
(398 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||D75093 macrolide-efflux determinant related PAB0754 - Pyroc... 774 0.0
pir||C71050 probable macrolide-efflux determinant - Pyrococcus h... 583 e-165
pir||B75087 multidrug resistance protein (multidrug-ef flux tran... 374 e-102
pir||D72388 hypothetical protein TM0342 - Thermotoga maritima (s... 264 1e-69
pir||H72265 hypothetical protein TM1336 - Thermotoga maritima (s... 174 1e-42
gb|AAB41436.1| (U83667) macrolide-efflux determinant [Streptococ... 128 1e-28
dbj|BAA89223.1| (AB011259) macrolide-efflux pump [Streptococcus ... 128 1e-28
gb|AAC44785.1| (U70055) macrolide-efflux protein [Streptococcus ... 116 4e-25
emb|CAA63510.1| (X92946) macrolide efflux protein [Lactococcus l... 108 1e-22
dbj|BAB07605.1| (AP001520) multidrug-efflux transporter [Bacillu... 101 1e-20
dbj|BAB04012.1| (AP001508) unknown conserved protein [Bacillus h... 100 4e-20
emb|CAA03986.1| (AJ000283) Tap protein [Mycobacterium fortuitum] 96 9e-19
pir||E69804 multidrug resistance protein homolog yfiS - Bacillus... 96 9e-19
gb|AAF74725.1|AF251288_2 (AF251288) MefEn2 [Bacteroides fragilis] 92 1e-17
emb|CAA10866.1| (AJ222587) YkuC protein [Bacillus subtilis] 88 2e-16
pir||H69864 macrolide-efflux protein homolog ykuC - Bacillus sub... 87 3e-16
sp|Q11060|YC58_MYCTU HYPOTHETICAL 43.3 KDA PROTEIN RV1258C >gi|7... 87 5e-16
dbj|BAB05758.1| (AP001514) unknown conserved protein in others [... 84 3e-15
pir||T28700 hypothetical protein - Streptomyces coelicolor >gi|3... 82 1e-14
pir||C70046 macrolide-efflux protein homolog yvqJ - Bacillus sub... 81 3e-14
gi|10954847 Hypothetical gene [Agrobacterium tumefaciens] >gi|64... 77 3e-13
pir||T45097 hypothetical protein [imported] - Mycobacterium smeg... 76 7e-13
emb|CAC11332.1| (AL445063) hypothetical membrane protein [Thermo... 76 9e-13
gb|AAD45543.1|U70376_8 (U70376) SpcT [Streptomyces flavopersicus] 75 2e-12
pir||A83308 probable MFS transporter PA2701 [imported] - Pseudom... 73 8e-12
pir||G75408 probable transport protein - Deinococcus radiodurans... 70 5e-11
>pir||D75093 macrolide-efflux determinant related PAB0754 - Pyrococcus abyssi
(strain Orsay) >gi|5458561|emb|CAB50049.1| (AJ248286)
MACROLIDE-EFFLUX DETERMINANT related [Pyrococcus abyssi]
Length = 398
Score = 774 bits (1976), Expect = 0.0
Identities = 398/398 (100%), Positives = 398/398 (100%)
Query: 1 MTKLGRDFWLFAVGRWISIAGWAIQDVAIPLYVLDKTGSGTMMSLFVMAELIPRILVNPI 60
MTKLGRDFWLFAVGRWISIAGWAIQDVAIPLYVLDKTGSGTMMSLFVMAELIPRILVNPI
Sbjct: 1 MTKLGRDFWLFAVGRWISIAGWAIQDVAIPLYVLDKTGSGTMMSLFVMAELIPRILVNPI 60
Query: 61 AGVIGDRYNRKYLMVGFDLIRGVLLFFVLFFNLLELEQLLVIQVIMSIFGSFFAAGTSGM 120
AGVIGDRYNRKYLMVGFDLIRGVLLFFVLFFNLLELEQLLVIQVIMSIFGSFFAAGTSGM
Sbjct: 61 AGVIGDRYNRKYLMVGFDLIRGVLLFFVLFFNLLELEQLLVIQVIMSIFGSFFAAGTSGM 120
Query: 121 FPDLVPKDRLMQANSILQMGTQVINIVSPVIGGAIYGLGGIKAAIFINAISFFGSGLFEI 180
FPDLVPKDRLMQANSILQMGTQVINIVSPVIGGAIYGLGGIKAAIFINAISFFGSGLFEI
Sbjct: 121 FPDLVPKDRLMQANSILQMGTQVINIVSPVIGGAIYGLGGIKAAIFINAISFFGSGLFEI 180
Query: 181 SIRYEWKGKGEKFAILREFLDGIKLIKSSKPLLILGSLSIILNALFSPLFAIVFPYIVRV 240
SIRYEWKGKGEKFAILREFLDGIKLIKSSKPLLILGSLSIILNALFSPLFAIVFPYIVRV
Sbjct: 181 SIRYEWKGKGEKFAILREFLDGIKLIKSSKPLLILGSLSIILNALFSPLFAIVFPYIVRV 240
Query: 241 VLRLSSIQFGSVQTALTLGMLLGNLIIASILKNSAGKHFMKAILIQELFILIVPFTPKLS 300
VLRLSSIQFGSVQTALTLGMLLGNLIIASILKNSAGKHFMKAILIQELFILIVPFTPKLS
Sbjct: 241 VLRLSSIQFGSVQTALTLGMLLGNLIIASILKNSAGKHFMKAILIQELFILIVPFTPKLS 300
Query: 301 YPRNYLVILTSAFAIGFFNVLVNIPIMTKLQTIVPREYRARFFSTLETLSMGATPLGMII 360
YPRNYLVILTSAFAIGFFNVLVNIPIMTKLQTIVPREYRARFFSTLETLSMGATPLGMII
Sbjct: 301 YPRNYLVILTSAFAIGFFNVLVNIPIMTKLQTIVPREYRARFFSTLETLSMGATPLGMII 360
Query: 361 VGPTIDKLGYFSVSITLTIVGIAISVYYWLRYSRILKL 398
VGPTIDKLGYFSVSITLTIVGIAISVYYWLRYSRILKL
Sbjct: 361 VGPTIDKLGYFSVSITLTIVGIAISVYYWLRYSRILKL 398
>pir||C71050 probable macrolide-efflux determinant - Pyrococcus horikoshii
>gi|3257514|dbj|BAA30197.1| (AP000005) 403aa long
hypothetical macrolide-efflux determinant [Pyrococcus
horikoshii]
Length = 403
Score = 583 bits (1486), Expect = e-165
Identities = 279/396 (70%), Positives = 337/396 (84%), Gaps = 3/396 (0%)
Query: 4 LGRDFWLFAVGRWISIAGWAIQDVAIPLYVLDKTGSGTMMSLFVMAELIPRILVNPIAGV 63
LGRDFWLF+VGRWIS AGW IQDVA+PLYVLDKTGSGTMMS FVMAELIPRI++NP+AGV
Sbjct: 3 LGRDFWLFSVGRWISTAGWTIQDVAVPLYVLDKTGSGTMMSAFVMAELIPRIILNPLAGV 62
Query: 64 IGDRYNRKYLMVGFDLIRGVLLFFVLFFNLLELEQLLVIQVIMSIFGSFFAAGTSGMFPD 123
IGDRYNRK+LMVGFDL RGVLLF ++ N+LEL +LL++QVIMS GSFF+AGTS MFPD
Sbjct: 63 IGDRYNRKHLMVGFDLARGVLLFLIIALNMLELRELLIVQVIMSAMGSFFSAGTSAMFPD 122
Query: 124 LVPKDRLMQANSILQMGTQVINIVSPVIGGAIYGLGGIKAAIFINAISFFGSGLFEISIR 183
LVPK+ LMQANSILQMGTQVIN++SP +GG IYGLGGI+AAI +NAISFFGSGLFEI IR
Sbjct: 123 LVPKEELMQANSILQMGTQVINVISPALGGLIYGLGGIRAAILVNAISFFGSGLFEILIR 182
Query: 184 YEWKGKGEKFAI---LREFLDGIKLIKSSKPLLILGSLSIILNALFSPLFAIVFPYIVRV 240
YEW+ K K I + EFL+ + LIK+S+ L ++ S S+ILNAL +PLFA+VFPY+VRV
Sbjct: 183 YEWRRKAGKLTITKVVEEFLEALNLIKNSQMLTVIISFSVILNALLNPLFAVVFPYMVRV 242
Query: 241 VLRLSSIQFGSVQTALTLGMLLGNLIIASILKNSAGKHFMKAILIQELFILIVPFTPKLS 300
V++LS+ QFG+VQT+LTLGML+GNLIIA IL+ SA KH KA+ IQE F+L++PFTP+L
Sbjct: 243 VVKLSAFQFGTVQTSLTLGMLVGNLIIAGILRESATKHIFKALAIQEFFLLMIPFTPRLY 302
Query: 301 YPRNYLVILTSAFAIGFFNVLVNIPIMTKLQTIVPREYRARFFSTLETLSMGATPLGMII 360
YP NY ILT F IG FNVLVNIPI+TKLQ VP EYRAR FSTLETL M ATP+GM +
Sbjct: 303 YPENYFAILTIVFIIGVFNVLVNIPILTKLQREVPEEYRARIFSTLETLVMSATPVGMAL 362
Query: 361 VGPTIDKLGYFSVSITLTIVGIAISVYYWLRYSRIL 396
+GP +DKLGY V+++LT++GI I++YYW+RYS++L
Sbjct: 363 IGPAVDKLGYLRVTLSLTLIGILITLYYWVRYSKLL 398
>pir||B75087 multidrug resistance protein (multidrug-ef flux transporter)
PAB0724 - Pyrococcus abyssi (strain Orsay)
>gi|5458511|emb|CAB49999.1| (AJ248286) MULTIDRUG
RESISTANCE PROTEIN (MULTIDRUG-EF FLUX TRANSPORTER)
[Pyrococcus abyssi]
Length = 418
Score = 374 bits (949), Expect = e-102
Identities = 191/395 (48%), Positives = 272/395 (68%), Gaps = 10/395 (2%)
Query: 4 LGRDFWLFAVGRWISIAGWAIQDVAIPLYVLDKTGSGTMMSLFVMAELIPRILVNPIAGV 63
+ R+FWLF GR+IS GWAIQ+VA+PLYVLD T S +M+LFV+A+LIP I+ PIAGV
Sbjct: 1 MNRNFWLFVAGRFISQLGWAIQEVALPLYVLDVTHSAKIMTLFVLADLIPSIITTPIAGV 60
Query: 64 IGDRYNRKYLMVGFDLIRGVLLFFVLFFNLLELEQLLVIQVIMSIFGSFFAAGTSGMFPD 123
GDRY+RK +MVGFDLIRGVLLF V+ FN L + LLV+QVIM+I +FF+AGT M+PD
Sbjct: 61 FGDRYDRKKIMVGFDLIRGVLLFLVIAFNFLTIRCLLVVQVIMAIMNAFFSAGTGAMYPD 120
Query: 124 LVPKDRLMQANSILQMGTQVINIVSPVIGGAIYGLGGIKAAIFINAISFFGSGLFEISIR 183
LV + L +ANSI+ + + +V P IGG +YG GGIK AI +NAISFFGSGLFEI I+
Sbjct: 121 LVKPEELERANSIVMSASIISRLVGPAIGGFVYGFGGIKLAILMNAISFFGSGLFEIFIK 180
Query: 184 YEWKGKG-EKFA-ILREFLDGIKLIKSSKPLLILGSLSIILNALFSPLFAIVFPYIVRVV 241
YEWK + E F+ +R+ +G+K I S+ + L L I+LNAL +P +I++PY +R +
Sbjct: 181 YEWKTRNIEGFSDFVRDIKEGLKFIMSNSFISTLIGLVILLNALGAPFASIIYPYAMREI 240
Query: 242 LRLSSIQFGSVQTALTLGMLLGNLIIASILKNSAGKHFMKAIL----IQELFILIVPFTP 297
L+ SS QFG V++A LG L+GNLI+ + L AG++ + L ++ +FILI+ +P
Sbjct: 241 LKFSSQQFGLVESAFMLGALIGNLIVGAFLGAKAGRYIFRLFLVNGAVELIFILII--SP 298
Query: 298 KLSYPRN--YLVILTSAFAIGFFNVLVNIPIMTKLQTIVPREYRARFFSTLETLSMGATP 355
L+ PRN ++++L +G ++N+P+ +KLQ VP E R R FST+E L+ A P
Sbjct: 299 FLALPRNSAFMLLLVLGATMGMAGAMINVPLASKLQRAVPSEIRGRVFSTMEMLARIANP 358
Query: 356 LGMIIVGPTIDKLGYFSVSITLTIVGIAISVYYWL 390
L +++VGP +D +G + + L + + +YYW+
Sbjct: 359 LSLVVVGPLVDTIGAWKTASFLWLGSGVVILYYWI 393
>pir||D72388 hypothetical protein TM0342 - Thermotoga maritima (strain MSB8)
>gi|4980843|gb|AAD35428.1|AE001715_4 (AE001715)
permease, putative [Thermotoga maritima]
Length = 413
Score = 264 bits (668), Expect = 1e-69
Identities = 156/396 (39%), Positives = 235/396 (58%), Gaps = 15/396 (3%)
Query: 6 RDFWLFAVGRWISIAGWAIQDVAIPLYVLDKTGSGTMMSLFVMAELIPRILVNPIAGVIG 65
R+F+L A+GR++SI G ++Q VAIPL+VLD T SG+ ++L +A ++PRIL PIAG++G
Sbjct: 9 RNFFLLALGRFVSILGSSVQAVAIPLFVLDLTHSGSAVALMTVAYMVPRILFTPIAGIVG 68
Query: 66 DRYNRKYLMVGFDLIRGVLLFF---VLFFNLLELEQLLVIQVIMSIFGSFFAAGTSGMFP 122
DR +RK+LMV D +RG L+ F + F N + L L V Q+ M+I + F T MFP
Sbjct: 69 DRGDRKFLMVSMDFLRGFLICFLALLAFRNSITLPVLYVSQIAMAIMDNLFDIPTGAMFP 128
Query: 123 DLVPKDRLMQANSILQMGTQVINIVSPVIGGAIYGLGGIKAAIFINAISFFGSGLFEISI 182
D+VP+D LM+ANSI+ M I+ P +GG IYG GI +N +SF S + EI I
Sbjct: 129 DIVPQDFLMRANSIMGMVRIFPQILGPALGGVIYGFYGIAIVFLVNGVSFVLSAISEIFI 188
Query: 183 RYEWK--GKGEKFA-ILREFLDGIKLIKSSKPLLILGSLSIILNALFSPLFAIVFPYIVR 239
Y K K KF+ IL + +G I + + + + ++ LN L SPLF +V+PY +R
Sbjct: 189 VYSRKVEKKPAKFSQILEDLKEGFLFIWNHELIRTILIFALFLNLLISPLFMVVYPYTIR 248
Query: 240 VVLRLSSIQFGSVQTALTLGMLLGNLIIASIL-KNSAGKHFMKAILIQELFILIVPFTPK 298
V++ S+ +FG ++T+ TLG LLGN +IAS L K + K +I + EL I+ + F
Sbjct: 249 EVMKFSAQEFGFLETSFTLGALLGNFLIASYLSKKNMWKAMKISIFLFELPIVFLGFLVM 308
Query: 299 LSYPRNYLVILTSAF----AIGFFNVLVNIPIMTKLQTIVPREYRARFFSTLETLSMGAT 354
+ N LV+ + F +GF N ++N+P+ T Q + P RAR FS L ++ G T
Sbjct: 309 PDFSLNRLVLFSLFFITFLIMGFLNPIINVPLDTAFQKMTPSHIRARAFSFLILVANGVT 368
Query: 355 PLGMIIVGPTIDKLG----YFSVSITLTIVGIAISV 386
PLG ++ G +D++ Y+ V +V + + V
Sbjct: 369 PLGSVLYGYLVDRVPVHFLYYVVGALSFLVAVLLLV 404
>pir||H72265 hypothetical protein TM1336 - Thermotoga maritima (strain MSB8)
>gi|4981896|gb|AAD36408.1|AE001788_3 (AE001788)
permease, putative [Thermotoga maritima]
Length = 390
Score = 174 bits (437), Expect = 1e-42
Identities = 108/386 (27%), Positives = 204/386 (51%), Gaps = 14/386 (3%)
Query: 4 LGRDFWLFAVGRWISIAGWAIQDVAIPLYVLDKTGSGTMMSLFVMAELIPRILVNPIAGV 63
+ R+ LFA G ++S+ G I VA+ ++ KTGS + LF+++ +P I+V+P AG
Sbjct: 1 MNRNLLLFASGSFVSLIGTRIYQVALAWWLYSKTGSSEYVGLFMISSFLPAIIVSPFAGT 60
Query: 64 IGDRYNRKYLMVGFDLIRGVL---LFFVLFFNLLELEQLLVIQVIMSIFGSFFAAGTSGM 120
+ DR++R+ +MV D++RGVL LF + +F+ L + LL++ V++S+F SFF +
Sbjct: 61 VVDRHSRRNMMVVMDILRGVLFMYLFLMEYFSELTMALLLIVTVLVSVFDSFFNPAVDSL 120
Query: 121 FPDLVPKDRLMQANSILQMGTQVINIVSPVIGGAIYGLGGIKAAIFINAISFFGSGLFEI 180
PDLV K+ L++ANS+ ++ + I+ P +G + + G+ I IN++SF SG+FE+
Sbjct: 121 LPDLVRKENLVRANSLYRLLKNLSKILGPALGSLLLKVVGLAGVILINSLSFLISGIFEM 180
Query: 181 SIRYE---WKGKGEKFAILREFLDGIKLIKSSKPLLILGSLSIILNALFSPLFAIVFPYI 237
I+ E K ++ + ++ + I+S + +L+ + I+N + ++ ++
Sbjct: 181 FIKVEEKHLKKVSKERNMWQDIKSALLYIRSVRFILVTILVIAIMNFFTGSMHVLLPEHV 240
Query: 238 VRVVLRLSSIQFGSVQTALTLGMLLGNLIIASILKNSAGKHFMKAILIQELFILIVPFTP 297
+ L S +G++ + L+ G L+ ++A+I ++ K ++ L + + T
Sbjct: 241 SK--LGKSEWVYGTLMSMLSFGGLIVTFLMATIRTRASVKTLGLNLVGYGLAVFVFAMT- 297
Query: 298 KLSYPRNYLVILTSAFAIGFFNVLVNIPIMTKLQTIVPREYRARFFSTLETLSMGATPLG 357
N+ ++ F IG F L NI ++T LQ +P E R + FS + +S P+
Sbjct: 298 -----GNHWLMFAMYFLIGIFQTLFNINVITLLQLAIPEEMRGKIFSLISAVSFSLLPVS 352
Query: 358 MIIVGPTIDKLGYFSVSITLTIVGIA 383
G + + IT ++ IA
Sbjct: 353 YGFFGFLSSYVATAHIFITTSMALIA 378
>gb|AAB41436.1| (U83667) macrolide-efflux determinant [Streptococcus pneumoniae]
Length = 405
Score = 128 bits (319), Expect = 1e-28
Identities = 101/388 (26%), Positives = 182/388 (46%), Gaps = 14/388 (3%)
Query: 6 RDFWLFAVGRWISIAGWAIQDVAIPLYVLDKTGSGTMMSLFVMAELIPRILVNPIAGVIG 65
R F+ G+ +S+ AI +AI Y+ +KTGS ++S+ + +P ++ P GV+
Sbjct: 9 RKFYAIWAGQAVSLITSAILQMAIIFYLTEKTGSAMVLSMASLVGFLPYAILGPAIGVLV 68
Query: 66 DRYNRKYLMVGFDLI---RGVLLFFVLFFNLLELEQLLVIQVIMSIFGSFFAAGTSGMFP 122
DR++RK +M+G DLI G +L V F L + ++++ I SI +F + + P
Sbjct: 69 DRHDRKKIMIGADLIIAAAGAVLAIVAFCMELPVWMIMIVLFIRSIGTAFHTPALNAVTP 128
Query: 123 DLVPKDRLMQANSILQMGTQVINIVSPVIGGAIYGLGGIKAAIFINAISFFGSGLFEISI 182
LVP+++L + Q + IVSP + +Y + + A I I+ + + + +
Sbjct: 129 LLVPEEQLTKCAGYSQSLQSISYIVSPAVAALLYSVWDLNAIIAIDVLGAVIASITVAIV 188
Query: 183 RYEWKGKGEKFA---ILREFLDGIKLIKSSKPLLILGSLSIILNALFSPLFAIVFPYIVR 239
R G + +RE +G+ +++ +K L L L + ++ P+ A+ FP I
Sbjct: 189 RIPKLGNQVQSLEPNFIREMKEGVVVLRQNKGLFALLLLGTLYTFVYMPINAL-FPLISM 247
Query: 240 VVLRLSSIQFGSVQTALTLGMLLGNLIIASILKNSAGKHFMKAILIQELFILIVPFTPKL 299
+ + + + GML G L++ + KH + ++ FI+
Sbjct: 248 EHFNGTPVHISITEISFAFGMLAGGLLLGRL--GGFEKHVL--LITSSFFIMGTSLAVSG 303
Query: 300 SYPRNYLVILTSAFAIGFFNVLVNIPIMTKL-QTIVPREYRARFFSTLETLSMGATPLGM 358
P N VI AI +V + T L Q + EY R FS + ++ A P+G+
Sbjct: 304 ILPPNGFVIFVVCCAIMGLSVPFYSGVQTALFQEKIKPEYLGRVFSLIGSIMSLAMPIGL 363
Query: 359 IIVGPTIDKLG--YFSVSITLTIVGIAI 384
I+ G DK+G ++ + + I+GIAI
Sbjct: 364 ILSGFFADKIGVNHWFLLSGILIIGIAI 391
>dbj|BAA89223.1| (AB011259) macrolide-efflux pump [Streptococcus pneumoniae]
Length = 402
Score = 128 bits (319), Expect = 1e-28
Identities = 101/388 (26%), Positives = 182/388 (46%), Gaps = 14/388 (3%)
Query: 6 RDFWLFAVGRWISIAGWAIQDVAIPLYVLDKTGSGTMMSLFVMAELIPRILVNPIAGVIG 65
R F+ G+ +S+ AI +AI Y+ +KTGS ++S+ + +P ++ P GV+
Sbjct: 9 RKFYAIWAGQAVSLITSAILQMAIIFYLTEKTGSAMVLSMASLVGFLPYAILGPAIGVLV 68
Query: 66 DRYNRKYLMVGFDLI---RGVLLFFVLFFNLLELEQLLVIQVIMSIFGSFFAAGTSGMFP 122
DR++RK +M+G DLI G +L V F L + ++++ I SI +F + + P
Sbjct: 69 DRHDRKKIMIGADLIIAAAGAVLAIVAFCMELPVWMIMIVLFIRSIGTAFHTPALNAVTP 128
Query: 123 DLVPKDRLMQANSILQMGTQVINIVSPVIGGAIYGLGGIKAAIFINAISFFGSGLFEISI 182
LVP+++L + Q + IVSP + +Y + + A I I+ + + + +
Sbjct: 129 LLVPEEQLTKCAGYSQSLQSISYIVSPAVAALLYSVWDLNAIIAIDVLGAVIASITVAIV 188
Query: 183 RYEWKGKGEKFA---ILREFLDGIKLIKSSKPLLILGSLSIILNALFSPLFAIVFPYIVR 239
R G + +RE +G+ +++ +K L L L + ++ P+ A+ FP I
Sbjct: 189 RIPKLGNQVQSLEPNFIREMKEGVVVLRQNKGLFALLLLGTLYTFVYMPINAL-FPLISM 247
Query: 240 VVLRLSSIQFGSVQTALTLGMLLGNLIIASILKNSAGKHFMKAILIQELFILIVPFTPKL 299
+ + + + GML G L++ + KH + ++ FI+
Sbjct: 248 EHFNGTPVHISITEISFAFGMLAGGLLLGRL--GGFEKHVL--LITSSFFIMGTSLAVSG 303
Query: 300 SYPRNYLVILTSAFAIGFFNVLVNIPIMTKL-QTIVPREYRARFFSTLETLSMGATPLGM 358
P N VI AI +V + T L Q + EY R FS + ++ A P+G+
Sbjct: 304 ILPPNGFVIFVVCCAIMGLSVPFYSGVQTALFQEKIKPEYLGRVFSLIGSIMSLAMPIGL 363
Query: 359 IIVGPTIDKLG--YFSVSITLTIVGIAI 384
I+ G DK+G ++ + + I+GIAI
Sbjct: 364 ILSGFFADKIGVNHWFLLSGILIIGIAI 391
>gb|AAC44785.1| (U70055) macrolide-efflux protein [Streptococcus pyogenes]
>gi|10119927|gb|AAG12998.1|AF227520_4 (AF227520)
macrolide-efflux protein A [Streptococcus pneumoniae]
Length = 405
Score = 116 bits (288), Expect = 4e-25
Identities = 99/388 (25%), Positives = 184/388 (46%), Gaps = 18/388 (4%)
Query: 8 FWLFAVGRWISIAGWAIQDVAIPLYVLDKTGSGTMMSLFVMAELIPRILVNPIAGVIGDR 67
F+ G+ +S+ AI +AI Y+ +KTGS ++S+ + +P + P GV+ DR
Sbjct: 11 FYTIWAGQAVSLITSAILQMAIIFYLTEKTGSAMVLSMASLLGFLPYAVFGPAIGVLVDR 70
Query: 68 YNRKYLMVGFDLI---RGVLLFFVLFFNLLELEQLLVIQVIMSIFGSFFAAGTSGMFPDL 124
++RK +M+G DLI G +L V F+ L + ++++ I SI +F + + P L
Sbjct: 71 HDRKKIMIGADLIIAAAGSVLTIVAFYMELPVWMVMIVLFIRSIGTAFHTPALNAVTPLL 130
Query: 125 VPKDRLMQANSILQMGTQVINIVSPVIGGAIYGLGGIKAAIFINAISFFGSGLFEISIRY 184
VP+++L + Q + IVSP + +Y + + A I I+ + + + +R
Sbjct: 131 VPEEQLTKCAGYSQSLQSISYIVSPAVAALLYSVWELNAIIAIDVLGAVIASITVAIVRI 190
Query: 185 EWKGKGEKFA---ILREFLDGIKLIKSSKPLLILGSLSIILNALFSPLFAIVFPYIVRVV 241
G + +RE +G+ +++ +K L L + + ++ P+ A+ FP I
Sbjct: 191 PKLGDRVQSLDPNFIREMQEGMAVLRQNKGLFALLLVGTLYMFVYMPINAL-FPLISMDY 249
Query: 242 LRLSSIQFGSVQTALTLGMLLGNLIIASILKNSAGKHFMKAILI-QELFILIVPFTPKLS 300
+ + + + GML+G L++ G + + +LI +F++ + T
Sbjct: 250 FNGTPVHISITEISFASGMLIGGLLLGLF-----GNYQKRILLITASIFMMGISLTISGL 304
Query: 301 YPRNYLVILTSAFAIGFFNVLVNIPIMTKL-QTIVPREYRARFFSTLETLSMGATPLGMI 359
P++ I AI +V + T L Q + EY R FS ++ A P+G+I
Sbjct: 305 LPQSGFFIFVVCCAIMGLSVPFYSGVQTALFQEKIKPEYLGRVFSLTGSIMSLAMPIGLI 364
Query: 360 IVGPTIDKLG---YFSVSITLTIVGIAI 384
+ D++G +F +S TL I+ IAI
Sbjct: 365 LSALFADRIGVNHWFLLSGTL-IICIAI 391
>emb|CAA63510.1| (X92946) macrolide efflux protein [Lactococcus lactis]
Length = 418
Score = 108 bits (268), Expect = 1e-22
Identities = 87/384 (22%), Positives = 176/384 (45%), Gaps = 11/384 (2%)
Query: 6 RDFWLFAVGRWISIAGWAIQDVAIPLYVLDKTGSGTMMSLFVMAELIPRILVNPIAGVIG 65
++F+LF +G+ ++ I AI Y+ +TG +++++ + ++P L++P G
Sbjct: 11 KNFYLFLIGQLLTGVTSMIVQYAIIWYLTLETGEESVLAIATLVGMLPMALLSPFVGPFI 70
Query: 66 DRYNRKYLMVGFDLIRGVLLFFVLFF----NLLELEQLLVIQVIMSIFGSFFAAGTSGMF 121
DR N+K+L++ +D + V+ + + ++ L + V I ++ + +
Sbjct: 71 DRINKKFLLISYDAVVAVIALGLFIYGINNDVYPLWMVFVTIGIRAVAQTAQMPTVQSIM 130
Query: 122 PDLVPKDRLMQANSILQMGTQVINIVSPVIGGAIYGLGGIKAAIFINAISF-FGSGLFEI 180
P +VP+D + + N + +I IVSP IG + I I ++ I F G+G+ +
Sbjct: 131 PTMVPEDEITRVNGQFGIIQSLIVIVSPGIGAFMVATMPIHWVILLDVIGFILGAGMLLL 190
Query: 181 SIRYEWKGKGEKFAILREFLDGIKLIKSSKPLLILGSLSIILNALFSPLFAIVFPYIVRV 240
E +GEK +++R+ L+G K+++ +KP+ + + + LF P ++ +P +
Sbjct: 191 VRIPEVASQGEKISVIRDTLEGFKILRENKPMWKMTLIGALFMLLFMPAMSL-YPLVTTK 249
Query: 241 VLRLSSIQFGSVQTALTLGMLLGNLIIASILKNSAGKHF-MKAILIQELFILIVPFTP-K 298
+ + G V+ ML+G+ + K + + A LI L I F P
Sbjct: 250 YFGGTIVHAGWVEVLFAAAMLIGSFAVGIFGKTKDRMPWIIAAYLIIGLSIGGSGFLPGN 309
Query: 299 LSYPRNYLVILTSAFAIGFFNVLVNIPIMTKLQTIVPREYRARFFSTLETLSMGATPLGM 358
++ +LV+ A +G +N+ I Q +Y R + L A P+G+
Sbjct: 310 MNGFWVFLVLNVFAGIVGQIYTTMNMAI---TQQSFEAQYLGRVMGIVSALMSIAGPVGL 366
Query: 359 IIVGPTIDKLGYFSVSITLTIVGI 382
I P + +G ++ + GI
Sbjct: 367 IFAAPVAESIGVQNMLVIAGFGGI 390
>dbj|BAB07605.1| (AP001520) multidrug-efflux transporter [Bacillus halodurans]
Length = 411
Score = 101 bits (250), Expect = 1e-20
Identities = 91/401 (22%), Positives = 169/401 (41%), Gaps = 17/401 (4%)
Query: 6 RDFWLFAVGRWISIAGWAIQDVAIPLYVLDKTGSGTMMSLFVMAELIPRILVNPIAGVIG 65
R F + + + +S G + + T S MS +A +IP++L N +AG
Sbjct: 8 RPFVVLWIAQSVSALGGTFTTFTVSWLMYQLTDSLVAMSGVWIAFMIPKLLTNLVAGPYL 67
Query: 66 DRYNRKYLMVGFDLIRGVLLF---FVLFFNLLELEQLLVIQVIMSIFGSFFAAGTSGMFP 122
DR+ K +MV + IR V F +L ++L L++ V+ I F
Sbjct: 68 DRFQYKVVMVASEWIRAVAFFVPTVLLVGDMLTAPVLIMAAVLTGIAEPLFRPAGMAYVA 127
Query: 123 DLVPKDRLMQANSILQMGTQVINIVSPVIGGAIYGLGGIKAAIFINAISFFGSGLFEISI 182
++P+ L + NSIL+ Q++ ++ P +GG + L G + I+ SG + +
Sbjct: 128 HILPEKHLQRGNSILEGTMQIVMLIGPALGGGLIVLVGPLPLLVFIVIALTVSGFLLLML 187
Query: 183 RYEWKGK-GEKFAILREFLDGIKLIKSSKPLLILGSLSIILNALFSPLFAIVFPYIVRVV 241
+ K ++ + L F +G+ K L +G L +++N + PY++
Sbjct: 188 DRVHRAKTNDRASWLTMFKEGMSFYKVYPVLFSVGLLMMMINFSSGAALPMFLPYVLE-H 246
Query: 242 LRLSSIQFGSVQTALTLGMLLGNLIIASILKNSAGKHFMKAILIQELFILIVPFTPKLSY 301
L + Q+G + +LGM+LG+ + + M L F+++ L +
Sbjct: 247 LHGTEFQYGLFMSVYSLGMVLGSFLCGLYPPPKNLRRVMLGYLTVSSFLMMA-----LGF 301
Query: 302 PRNYLVILTSAFAIGFFNVLVNIPIMTKLQTIVPREYRARFFSTLETLSMGATPLGMIIV 361
+ + + A GFF + I T Q VP R R F+ L+ A PLG +
Sbjct: 302 ITSIWIAIGIATMQGFFAMAFTINNTTFYQRRVPEHLRGRVFTVRALLAQSAIPLGAGVG 361
Query: 362 GPTIDKLGYFSVSITL-------TIVGIAISVYYWLRYSRI 395
G + + + + L T++ ++V+Y L + +
Sbjct: 362 GLLAEAYRFQVLFLILGGLMLVSTLLAWRMNVFYQLNHQPV 402
>dbj|BAB04012.1| (AP001508) unknown conserved protein [Bacillus halodurans]
Length = 418
Score = 100 bits (246), Expect = 4e-20
Identities = 93/387 (24%), Positives = 171/387 (44%), Gaps = 24/387 (6%)
Query: 8 FWLFAVGRWISIAGWAIQDVAIPLYVLDKTGSGTMMSLFVMAELIPRILVNPIAGVIGDR 67
F L V S ++I + YV+D+ G T + + +MA +PR+L+ I GV+ DR
Sbjct: 26 FLLLWVASIFSGLSFSIYFLTKSWYVVDELGLKTFLGVVLMAMTVPRVLLMMIGGVLADR 85
Query: 68 YNRKYLMVGFDLIRGVLLF--FVL-FFNLLELEQLLVIQVIMSIFGSFFAAGTSGMFPDL 124
+ R +M + R VLLF F+L F ++ + L+ + I +FF + P +
Sbjct: 86 FRRSTIMFCSLITRSVLLFGMFILQFLGVINIWTLIGFAFCIGILDAFFWPANYAILPSI 145
Query: 125 VPKDRLMQANSILQMGTQVINIVSPVIGGAIYGLGGIKAAIFINAISFFGSG---LFEIS 181
V KD L +ANS LQ + I+ P+I G + + + IF+ + G +F +
Sbjct: 146 VKKDHLTRANSFLQSTNHLTLIIGPMIAGWLITITAYE-WIFVTIMCLLIIGAILIFRVK 204
Query: 182 IRYEWKGKGEKFAILREFLDGIKLIKSSKPLLILGSLSIILNALFSPLFAIVFPYIVRVV 241
++ + L++ +G ++ S LL L +S+ +N + + P IV
Sbjct: 205 EPFDKPETKRLPSPLKDLTEGYSYLRHSPVLLSLMWMSVFVNFFITGPGTMAIPLIVEER 264
Query: 242 LRLSSIQFGSVQTALTLGMLLGNLIIASI-LKNSAGKHFMKAILIQELFILIVPFTPKLS 300
L+ ++ +++ + G++LG ++I I L++ G + + + + I ++ L
Sbjct: 265 LKGDPLELSYLESTIAGGLILGAIMIGIINLRSKRGLLIIIRLTVMGVAIALLGQVVSLW 324
Query: 301 YPRNYLVILTSAFAIGFFNVLVNIPIMTKLQTIVPREYRARFFSTLETLSMGATPLGMII 360
L IL +IG +IP +Q + R + T S G PL
Sbjct: 325 QAIFVLAILGMGISIG------DIPARAVVQEKTDFDKIGRVMGMMSTASSGLIPL---- 374
Query: 361 VGPTIDKLGYFSVSITLTIVGIAISVY 387
G SV+++L + +I +Y
Sbjct: 375 ------SYGMTSVALSLNLSISSILLY 395
>emb|CAA03986.1| (AJ000283) Tap protein [Mycobacterium fortuitum]
Length = 409
Score = 95.6 bits (234), Expect = 9e-19
Identities = 97/381 (25%), Positives = 173/381 (44%), Gaps = 27/381 (7%)
Query: 20 AGWAIQDVAIPLYVLDKTGSGTMMSLFVMAELIPRILVNPIAGVIGDRYNRKYLMVGFDL 79
AG I VA P VL GS S+ MA +P ++ IAG D R+ + + DL
Sbjct: 21 AGNGITIVAFPWLVLQHNGSALDASIVAMAGTLPLLVATLIAGAAVDYLGRRRVSMISDL 80
Query: 80 IRGVLLFFVLFFNLL---ELEQLLVIQVIMSIFGSFFAAGTSG---MFPDLVPKD--RLM 131
+ + + V L+ + + V+ V+ + F AG + M P+ + L
Sbjct: 81 LSALSVAAVPVLALIFGVDAVNVAVLAVLAGLGAFFDPAGMTARETMLPEAAGRAGWTLD 140
Query: 132 QANSILQMGTQVINIVSPVIGGAIYG-LGGIKAAIFINAISFFGSGLFEISIRYEWKGKG 190
ANS+ + + IV P IGG + LGGI +++ A +F S L +R E G
Sbjct: 141 HANSVYEAVFNLGYIVGPGIGGLMIATLGGINT-MWVTAGAFCCSILAISVLRLEGAGAP 199
Query: 191 EKF----AILREFLDGIKLIKSSKPLLILGSLSIILNALFSPLFAIVFPYIVRVVLRLSS 246
++ A+L ++G++ + + L L + ++ L+ P+ +++FP R
Sbjct: 200 DRSVLTEAVLAGIVEGLRFVWYTPVLRTLAIVDLVATGLYMPMESVLFPKYFTD--RNEP 257
Query: 247 IQFGSVQTALTLGMLLGNLIIASILKNSAGKHFM-KAILIQELFILIVPFTPKLSYPRNY 305
+ G V AL++G LLG L A + + + + M A++ + + ++ F P L
Sbjct: 258 TELGWVLMALSIGGLLGALGYAVMSRYMSRRATMLTAVITLGVAMTVIAFLPPLP----- 312
Query: 306 LVILTSAFAIGFFNVLVNIPIMTKLQTIVPREYRARFFSTLETLSMGATPLGMIIVGPTI 365
+IL +GF + +QT P+ R R + +L+ A PLG+I+ GP
Sbjct: 313 -LILVLCAIVGFVYGPIAPIYNYVMQTTAPQHLRGRVVGVMGSLAYAAGPLGLILAGPLA 371
Query: 366 DKLG----YFSVSITLTIVGI 382
D G + ++S+ + ++G+
Sbjct: 372 DAAGLHATFLALSLPMLLLGV 392
>pir||E69804 multidrug resistance protein homolog yfiS - Bacillus subtilis
>gi|2633162|emb|CAB12667.1| (Z99108) similar to
multidrug resistance protein [Bacillus subtilis]
>gi|2804523|dbj|BAA24459.1| (D85082) YfiS [Bacillus
subtilis]
Length = 417
Score = 95.6 bits (234), Expect = 9e-19
Identities = 94/369 (25%), Positives = 158/369 (42%), Gaps = 12/369 (3%)
Query: 18 SIAGWAIQDVAIPLYVLDKTGSGTMMSLFVMAELIPRILVNPIAGVIGDRYNRKYLMVGF 77
S+ W + L S MSL +M+ +P I++ P++G++ DR++RK +M
Sbjct: 23 SLGDWLHILAVLTLAAFQLHASPLDMSLLMMSFALPVIVLGPVSGLLADRFDRKTIMFLS 82
Query: 78 DLIRGVLLFFVLFFNLLELEQLLVIQVIMSIFGSFFAAGTSGMFPDLVPKDRLMQANSIL 137
++ R + + ++ + EL QL V+ + S F S F +G +L P+ + QA S+
Sbjct: 83 EIGRALTVISCVYVS--ELWQLYVLLSVQSCFSSLFLPAKNGKLKELAPEAHIQQAVSVS 140
Query: 138 QMGTQVINIVSPVIGGAIYGLGGIKAAIFINAISFFGSGLFEISI-RYEWKGKG----EK 192
+ I P +GG + I + +INA +FF S + + R + K EK
Sbjct: 141 SIIDNSSKIFGPALGGTLIAAFSIHSVFYINAGAFFLSAVILFFLPRDAFLQKANTPQEK 200
Query: 193 FAILREFLDGIKLIKSSKPLLILGSLSIILNALFSPLFAIVFPYIVRVVLRLSSIQFGSV 252
A L +G++ +K PLL+ G L+ + + ++R G
Sbjct: 201 TAALTSIKEGLQFLK-RMPLLLTGLLTACVVLFVLQIGDSQAIILIRSFSGAPPELAGWC 259
Query: 253 QTALTLGMLLGNLIIASILKNSAGKHFMKAILIQELFILIVPFTPKLSYPRNYLVILTSA 312
GMLL I S +F L+ L PF + L I +
Sbjct: 260 MAVSGAGMLLTAAITGRRRITSYLLYFSAGTLLLGLATGGAPFLSGMGIAGITLFIF-AF 318
Query: 313 FAIGFFNVLVNIPIMTKLQTIVPREYRARFFSTLETLSMGATPLGMIIVGPTIDKLGYFS 372
F +G LV+IP +QT VP +Y R F +++ + A+ LGM G + +G
Sbjct: 319 FIMGAAFGLVHIPFQILVQTTVPVDYSGRVFGAIQSATTLASILGMAGGGVLAEWIG--- 375
Query: 373 VSITLTIVG 381
VS+ + G
Sbjct: 376 VSLAFLVCG 384
>gb|AAF74725.1|AF251288_2 (AF251288) MefEn2 [Bacteroides fragilis]
Length = 401
Score = 92.1 bits (225), Expect = 1e-17
Identities = 82/369 (22%), Positives = 164/369 (44%), Gaps = 10/369 (2%)
Query: 10 LFAVGRWISIAGWAIQDVAIPLYVLDKTGSGTMMSLFVMAELIPRILVNPIAGVIGDRYN 69
+ +G+ ISI I +I ++ ++ S T +SL ++A +P+ ++ AGV DR+N
Sbjct: 10 VIGIGQLISILTSTIVGFSIIFWISNEFKSPTALSLAILAGFLPQFVLGLFAGVYVDRWN 69
Query: 70 RKYLMVGFDLIRG---VLLFFVLFFNLLELEQLLVIQVIMSIFGSFFAAGTSGMFPDLVP 126
RK M DL + LF V+ +L ++ SI +F A P LVP
Sbjct: 70 RKKTMFYSDLFIAFCTLCLFIVITKGYKDLSFFYLLTACRSIGSTFHAPALQASIPLLVP 129
Query: 127 KDRLMQANSILQMGTQVINIVSPVIGGAIYGLGGIKAAIFINAISFFGSGLFEISIRYEW 186
K L++ + + +++PV+G ++ I+ + I+ I + L + ++
Sbjct: 130 KHHLVRVSGLYHSIQSFSEVIAPVVGASLVVWLPIQYILLIDVIGAVAACLTLLCVQIPS 189
Query: 187 KGKGEKFA-ILREFLDGIKLIKSSKPLLILGSLSIILNALFSPLFAIVFPYIVRVVLRLS 245
K + +E + + ++ + +L L ++ + P+F + FP++ + +
Sbjct: 190 LQKTKVLPDFKKELTEWLHTLRRTMGILPLFVCFTLVTFVLMPVFTL-FPFMTLLHFNGN 248
Query: 246 SIQFGSVQTALTLGMLLGNLIIA-SILKNSAGKHFMKAILIQELFILIVPFTPKLSYPRN 304
+Q G V+ G LLG L++A LK+ A +I L+++ + P ++
Sbjct: 249 ILQMGVVEMGWGSGALLGGLVLACKALKSKQTLVMHTAYVILGLYLISASYLPSSAFIGF 308
Query: 305 YLVILTSAFAIGFFNVLVNIPIMTKLQTIVPREYRARFFSTLETLSMGATPLGMIIVGPT 364
+ T A ++ L + +Q + + R FS + +LS + LG++ G
Sbjct: 309 VCLTFTGGIAYSIYHAL----FIAIIQQNLASDMLGRTFSLIFSLSTFPSMLGIVASGYW 364
Query: 365 IDKLGYFSV 373
++ G SV
Sbjct: 365 VEAWGITSV 373
>emb|CAA10866.1| (AJ222587) YkuC protein [Bacillus subtilis]
Length = 430
Score = 88.2 bits (215), Expect = 2e-16
Identities = 100/387 (25%), Positives = 167/387 (42%), Gaps = 36/387 (9%)
Query: 21 GWAIQDVAIPLYVLDKTGSGTMMSLFVMAEL---IPRILVNPIAGVIGDRYNRKYLMVGF 77
G + ++A ++LD+ S S +AEL +P I V I GV+ DR++RK +
Sbjct: 22 GTTVGNMAFAFFLLDRFSS--QPSYTTLAELMYSLPTIFVFLIVGVVADRFDRKKVAENC 79
Query: 78 DLIRG---VLLFFVLFFNLLELEQLLVIQVIMSIFGSFFAAGTSGMFPDLVPKDRLMQAN 134
D IR V+LFF LF + L + I I S FF + + ++PK+ +A
Sbjct: 80 DWIRAGLTVVLFFTLFTGNIPL--VFCILFIRSAVTKFFFPAENSLVQAILPKEHYAKAA 137
Query: 135 SILQMGTQVINIVSPVIGGAIYGLGGIKAAIFINAISFFGSGLFEISIR----------- 183
+ QM + + IG +Y GI+ AI ++ +SF SGL S R
Sbjct: 138 GLNQMLFSIFMVFGVGIGAFMYNTIGIEGAIILDFVSFIISGLLIRSCRIPKEARQPNGA 197
Query: 184 YEWKGKGEKFAILREFLDGIKLIKSSKPLLILGSLSIILNALFSPLFAIVFPYIVRVVLR 243
+ W+ K +I +F +GI I +K L L + + FA++ + ++ L
Sbjct: 198 FSWRKTSVKDSI-NDFREGILYILKNKLLASL-IFGFFIFGFVNGGFAVLPMFTMKYGLA 255
Query: 244 LSSIQFGSVQTALTLGM-LLGNLIIASILKNSAGKHFMKAILIQELFILIVPFTPKLSYP 302
++ + + LG LL +I +++ HF+ +I I +LI L Y
Sbjct: 256 PDRYEWHTSVFTIALGFGLLAGSVIGTLISKKVKPHFLMSIPIFIAGLLIF----VLGYT 311
Query: 303 RNYLVILTSAFAIGFFNVLVNIPIMTKLQTIVPREYRAR-------FFSTLETLSMGATP 355
V +AFA+G +NI I + IV + R F ++L++G
Sbjct: 312 NILWVYYAAAFALGMCIGPINIAIGGWMPKIVHPKLMGRVSGMQDPFMMFAQSLTLGLVA 371
Query: 356 LGMIIVGPTIDKLGYFSVSITLTIVGI 382
L ID L Y+ + + + +V I
Sbjct: 372 LLFPKFVSNIDYL-YYGMGVIILLVFI 397
>pir||H69864 macrolide-efflux protein homolog ykuC - Bacillus subtilis
>gi|2633774|emb|CAB13276.1| (Z99111) similar to
macrolide-efflux protein [Bacillus subtilis]
Length = 430
Score = 87.4 bits (213), Expect = 3e-16
Identities = 100/387 (25%), Positives = 167/387 (42%), Gaps = 36/387 (9%)
Query: 21 GWAIQDVAIPLYVLDKTGSGTMMSLFVMAEL---IPRILVNPIAGVIGDRYNRKYLMVGF 77
G + ++A ++LD+ S S +AEL +P I V I GV+ DR++RK +
Sbjct: 22 GTTVGNMAFAFFLLDRFSS--QPSYTTLAELMYSLPTIFVFLIVGVVPDRFDRKKVAENC 79
Query: 78 DLIRG---VLLFFVLFFNLLELEQLLVIQVIMSIFGSFFAAGTSGMFPDLVPKDRLMQAN 134
D IR V+LFF LF + L + I I S FF + + ++PK+ +A
Sbjct: 80 DWIRAGLTVVLFFTLFTGNIPL--VFCILFIRSAVTKFFFPAENSLVQAILPKEHYAKAA 137
Query: 135 SILQMGTQVINIVSPVIGGAIYGLGGIKAAIFINAISFFGSGLFEISIR----------- 183
+ QM + + IG +Y GI+ AI ++ +SF SGL S R
Sbjct: 138 GLNQMLFSIFMVFGVGIGAFMYNTIGIEGAIILDFVSFIISGLLIRSCRIPKEARQPNGP 197
Query: 184 YEWKGKGEKFAILREFLDGIKLIKSSKPLLILGSLSIILNALFSPLFAIVFPYIVRVVLR 243
+ W+ K +I +F +GI I +K L L + + FA++ + ++ L
Sbjct: 198 FSWRKTSVKDSI-NDFREGILYILKNKLLASL-IFGFFIFGFVNGGFAVLPMFTMKYGLA 255
Query: 244 LSSIQFGSVQTALTLGM-LLGNLIIASILKNSAGKHFMKAILIQELFILIVPFTPKLSYP 302
++ + + LG LL +I +++ HF+ +I I +LI L Y
Sbjct: 256 PDRYEWHTSVFTIALGFGLLAGSVIGTLISKKVKPHFLMSIPIFIAGLLIF----VLGYT 311
Query: 303 RNYLVILTSAFAIGFFNVLVNIPIMTKLQTIVPREYRAR-------FFSTLETLSMGATP 355
V +AFA+G +NI I + IV + R F ++L++G
Sbjct: 312 NILWVYYAAAFALGMCIGPINIAIGGWMPKIVHPKLMGRVSGMQDPFMMFAQSLTLGLVA 371
Query: 356 LGMIIVGPTIDKLGYFSVSITLTIVGI 382
L ID L Y+ + + + +V I
Sbjct: 372 LLFPKFVSNIDYL-YYGMGVIILLVFI 397
>sp|Q11060|YC58_MYCTU HYPOTHETICAL 43.3 KDA PROTEIN RV1258C >gi|7477990|pir||B70753
probable efflux protein - Mycobacterium tuberculosis
(strain H37RV) >gi|1480328|emb|CAB00894.1| (Z77137)
hypothetical protein Rv1258c [Mycobacterium
tuberculosis]
Length = 419
Score = 86.6 bits (211), Expect = 5e-16
Identities = 85/376 (22%), Positives = 160/376 (41%), Gaps = 21/376 (5%)
Query: 17 ISIAGWAIQDVAIPLYVLDKTGSGTMMSLFVMAELIPRILVNPIAGVIGDRYNRKYLMVG 76
++ AG + VA P VL + GS S+ A ++P + +AG D + R+ + +
Sbjct: 18 MAAAGDGVSIVAFPWLVLQREGSAGQASIVASATMLPLLFATLVAGTAVDYFGRRRVSMV 77
Query: 77 FDLIRGVLLF---FVLFFNLLELEQLLVIQVIMSIFGSFFAAGTS---GMFPDLVPKD-- 128
D + G + V + + +LV+ V+ ++ +F AG + M P+ +
Sbjct: 78 ADALSGAAVAGVPLVAWGYGGDAVNVLVLAVLAALAAAFGPAGMTARDSMLPEAAARAGW 137
Query: 129 RLMQANSILQMGTQVINIVSPVIGGAIYGLGGIKAAIFINAISFFGSGLFEISIRYEWKG 188
L + N + + IV P IGG + G ++I A +F S L +++ E G
Sbjct: 138 SLDRINGAYEAILNLAFIVGPAIGGLMIATVGGITTMWITATAFGLSILAIAALQLEGAG 197
Query: 189 K----GEKFAILREFLDGIKLIKSSKPLLILGSLSIILNALFSPLFAIVFPYIVRVVLRL 244
K ++ +G++ + + + L LG + + + AL+ P+ +++FP
Sbjct: 198 KPHHTSRPQGLVSGIAEGLRFVWNLRVLRTLGMIDLTVTALYLPMESVLFPKY--FTDHQ 255
Query: 245 SSIQFGSVQTALTLGMLLGNLIIASILKNSAGKHFMK-AILIQELFILIVPFTPKLSYPR 303
+Q G A+ G L+G L A + + M A+L L +++ F P L
Sbjct: 256 QPVQLGWALMAIAGGGLVGALGYAVLAIRVPRRVTMSTAVLTLGLASMVIAFLPPLP--- 312
Query: 304 NYLVILTSAFAIGFFNVLVNIPIMTKLQTIVPREYRARFFSTLETLSMGATPLGMIIVGP 363
VI+ +G + +QT + R R + +L+ A PLG+++ GP
Sbjct: 313 ---VIMVLCAVVGLVYGPIQPIYNYVIQTRAAQHLRGRVVGVMTSLAYAAGPLGLLLAGP 369
Query: 364 TIDKLGYFSVSITLTI 379
D G + + L +
Sbjct: 370 LTDAAGLHATFLALAL 385
>dbj|BAB05758.1| (AP001514) unknown conserved protein in others [Bacillus
halodurans]
Length = 418
Score = 83.9 bits (204), Expect = 3e-15
Identities = 78/340 (22%), Positives = 153/340 (44%), Gaps = 13/340 (3%)
Query: 8 FWLFAVGRWISIAGWAIQDVAIPLYVLDKTGSGTMMSLFVMAELIPRILVNPIAGVIGDR 67
FW+ A + +S + + I V ++ S +++L ++ IP+I+ +AGV D
Sbjct: 15 FWVLA--QIVSPIAESFAALLITWTVWQQSSSTGILALTLLLAAIPQIIFGVVAGVATDW 72
Query: 68 YNRKYLMVGFDLIRGV---LLFFVLFFNLLELEQLLVIQVIMSIFGSFFAAGTSGMFPDL 124
+NRK++++ ++IR V LL + F LL ++ + F P +
Sbjct: 73 FNRKHIVMLCNVIRAVIMILLGMLAFSQLLNELVFMLASFSLGFLRLFAMTAYRAAMPGI 132
Query: 125 VPKDRLMQANSILQMGTQVINIVSPVIGGAIYGLGGIKAAIFINAISFFGSGLFEISIRY 184
V D+LM+AN+I ++ PV G L + +NAI F S I +
Sbjct: 133 VHSDQLMKANAITNSCRMAFWLIGPVFAGFCLTLLNTGQIMIMNAILFIVSVFLLIPVHI 192
Query: 185 -EWKGKGEKFAILREFLDGIKLIKSSKPLLILGSLSIILNALFSPLFAIVFPYIVRVVLR 243
+ K + + + ++ G++L+ + L+ ++ F A + +V +
Sbjct: 193 KQAKVEQHQKHMFKDIAVGLRLVTQDR-LIYSVLMTFAAFTCFGRGIAHLGNLMVSNEIG 251
Query: 244 LSSIQFGSVQTALTLGMLLGNLIIASILKNSAGKHFMKAILIQELFILIVPFTPKLSYPR 303
L S FG + +A G L+ L++A + ++ + M A L+ + L +PF+ L P
Sbjct: 252 LDSSGFGILSSADGFGYLIAGLLLARLSIKNSFRTMMLAWLLGGIVFLFMPFSSALWLP- 310
Query: 304 NYLVILTSAFAIGFFNVLVNIPIMTKLQTIVPREYRARFF 343
++L F +G V++P++T +Q V ++ + F
Sbjct: 311 --FILL---FIVGMSQPFVDVPLVTMIQKRVADQHLGKVF 345
>pir||T28700 hypothetical protein - Streptomyces coelicolor
>gi|3127851|emb|CAA18917.1| (AL023496) hypothetical
protein [Streptomyces coelicolor A3(2)]
Length = 630
Score = 81.9 bits (199), Expect = 1e-14
Identities = 93/401 (23%), Positives = 162/401 (40%), Gaps = 37/401 (9%)
Query: 3 KLGRDFWLFAVGRWISIAGWAIQDVAIPLYVLDKTGSGTMMSLFVMAELIPRILVNPIAG 62
+LG F LF S I +A+PL L + S + +A +P ++ AG
Sbjct: 16 RLGPPFRLFQSAVVSSDLADGIYKIAVPLLALGISRSAVAVGAVGLAVRLPWLIATLPAG 75
Query: 63 VIGDRYNRKYLMVGFDLIRGVLLFFVLFF---NLLELEQLLVIQVIMSIFGSFFAAGTSG 119
V+ DRY + +M +R L+ + + L L L+V ++ G F
Sbjct: 76 VLADRYPPRSVMRWASAVRLPLVAAMCALAATDRLPLWALVVTAFLIGCAGIFVDVAAQS 135
Query: 120 MFPDLVPKDRLMQANSILQMGTQVI--NIVSPVIGGAIYGL---GGIKAAIFINAISFFG 174
P LVP +L +AN+ LQ TQ+ ++ P +GG + L GG+ + + ++ +G
Sbjct: 136 QLPRLVPVGQLPKANASLQ-STQMFLAQLIGPALGGYVVALGSGGGLAVVVALYVVTVWG 194
Query: 175 SGLFEISIRYEWKG---------------KGEKFAILREFLDGIKLIKSSKPLLILGSLS 219
GL ++ G + +++ E +G++ + L L + +
Sbjct: 195 LGLLPAAVEQAAAGHARPATGPARAGGGRRSSFGSLVAELGEGLRYFRGRGDLARLATAA 254
Query: 220 IILNALFSPLFAIVFPYIVRV-VLRLSSIQFGSVQTALTLGMLLGNLIIASILKNSAGKH 278
+ N +S ++ + VR L LS +G + T L +G +L L+ IL
Sbjct: 255 AVNNLSYSMCLTMLPLWAVRPGRLGLSETGYGLLLTFLAVGSILAGLVTGRILDAVGDGP 314
Query: 279 FMK--AILIQELFI-LIVPFTPKLSYPRNYLVILTSAFAIGFFNVLVNIPIMTKLQTIVP 335
M+ A L+ F+ L VP P VI F G +++ N+ + + Q +P
Sbjct: 315 VMRFGAPLLGLCFLALAVPAVP---------VIALGLFVYGLVSMVWNVTVTSYRQATIP 365
Query: 336 REYRARFFSTLETLSMGATPLGMIIVGPTIDKLGYFSVSIT 376
R + L+ G P G + G G V +T
Sbjct: 366 LPLFGRVNAAYRWLTWGVIPFGSLFGGTLAATAGTTWVFLT 406
>pir||C70046 macrolide-efflux protein homolog yvqJ - Bacillus subtilis
>gi|2635811|emb|CAB15304.1| (Z99120) similar to
macrolide-efflux protein [Bacillus subtilis]
>gi|2832815|emb|CAA11739.1| (AJ223978) putative
macrolide-efflux determinant, YvqJ [Bacillus subtilis]
Length = 422
Score = 80.8 bits (196), Expect = 3e-14
Identities = 82/397 (20%), Positives = 161/397 (39%), Gaps = 23/397 (5%)
Query: 6 RDFWLFAVGRWISIAGWAIQDVAIPLYVLDKTGSGTM-MSLFVMAELIPRILVNPIAGVI 64
R+F R + I+G +I L+ L G G + +L + +P ++ P+ G
Sbjct: 13 RNFNYLFFSRIVKISGDMFAFNSI-LWFLIYDGKGAIGTALLIAVTFLPEAVLAPVTGPF 71
Query: 65 GDRYNRKYLMVGFDLIRGVLLFFVL---FFNLLELEQLLVIQVIMSIFGSFFAAGTSGMF 121
+ K+ M DL R ++ + F L ++ + ++ S G+ + + +
Sbjct: 72 MKQTTLKFWMYFSDLTRAAIVLIIPLCHFAGFSPLWFVMTLMIVHSATGAAYNPASIALI 131
Query: 122 PDLVPKDRLMQANSILQMGTQVINIVSPVIGGAIYGLGGIKAAIFINAISFFGSGLFEIS 181
P +V + + +AN++LQ Q++ + + + GA + I + + SG +
Sbjct: 132 PQIVNEQGIQKANAVLQSSAQIVRLGAVTLCGAFLTFISPSYTMLIALVLYLVSGFLVLF 191
Query: 182 IRYEWKGKGEKFAILRE-------FLDGIKLIKSSKPLLILGSLSIILNALFSPLFAIVF 234
I+Y + A++ + G +L++ + L L I +N +P A+
Sbjct: 192 IKYTAVESQSESAVVTQRGTYIGRLKRGFRLVRKHQILYPLAIYCIFMNFAAAPWEALSA 251
Query: 235 PYIVRVVLRLSSIQFGSVQTALTLGMLLGNLIIASILKNSAGKHFMKAILIQELFILIVP 294
Y+ L I + ++ G L ++A + N G F+ A +I+ I
Sbjct: 252 VYVAE-DLNGQPIVYSLLKATTAAGAFLLGFVLAKVKVNRYGLLFVTAGIIEGFAFFITG 310
Query: 295 FTPKLSYPRNYLVILTSAFAIGFFNVLVNIPIMTKLQTIVPREYRARFFSTLETLSMGAT 354
L ++ +AF G VN+P T +QT V E + + ++ + +S +
Sbjct: 311 MNTFLP------LVFFAAFTFGAAVSAVNVPEYTIIQTSVDSEDQPQVYAVIHMISNISI 364
Query: 355 PLGMIIVGPTIDKLGYFSV----SITLTIVGIAISVY 387
P G +I G + G V I I GI I ++
Sbjct: 365 PAGAVICGYAANAFGSGKVIAVGGIVEIIAGIGILLF 401
>gi|10954847 Hypothetical gene [Agrobacterium tumefaciens]
>gi|6498200|dbj|BAA87652.1| (AB016260) Hypothetical gene
[Agrobacterium tumefaciens]
Length = 405
Score = 77.3 bits (187), Expect = 3e-13
Identities = 77/362 (21%), Positives = 155/362 (42%), Gaps = 15/362 (4%)
Query: 27 VAIPLYVLDKTGSGTMMSLFVMAELIPRILVNPIAGVIGDRYNRKYLMVGFDLIRGVLLF 86
+ + L+VL + S + A ++P ++V+PIAGV+ DR + V D+I +
Sbjct: 35 LTLVLFVLARFSSPALAGWLTFAAIVPGLMVSPIAGVLLDRVGPT-IAVRIDMIASAIFI 93
Query: 87 FVL----FFNLLELEQLLVIQVIMSIFGSFFAAGTSGMFPDLVPKDRLMQANSILQMGTQ 142
+ + N L + ++ S+ G AAGT + P LVP L +AN++
Sbjct: 94 AAISTVSWLNWTTPPVLFFLVILFSLAGPLGAAGTRTLLPRLVPSHALDRANALDTAVYA 153
Query: 143 VINIVSPVIGGAIYGLGGIKAAIFINAISFFGSGLFEISIRYEWKGKGEKFAILREFLDG 202
V+++V P + G I G ++A+ + A+ + G+ + + + + +R+ L+G
Sbjct: 154 VVDVVGPAMAGIIVAWLGPESAMSMIALFYAGAAICMSLVPLLPGLASGQASFMRQTLEG 213
Query: 203 IKLIKSSKPLLILGSLSIILNALFSPLFAIVFPYIV-RVVLRLSSIQFGSVQTALTLGML 261
I+++ L L + + L+ +V ++ + S G + A+ +
Sbjct: 214 IQIVARQPTLRGLAISYSMYQITWGVLYVVVPVFVANHYDTSIGSSVTGFLWAAMGIAGG 273
Query: 262 LGNLIIASILKNSAGKHFMKAILIQELFILIVPFTPKLSYPRNYLVILTSAFAIGFFNVL 321
+G L I +H M AI + + P + + + ++ + G +
Sbjct: 274 IGALFAGHIRTTGRERHIM-AIGMVITALAAWPVAAEFGFGGLAIGLMLA----GVMSGP 328
Query: 322 VNIPIMTKLQTIVPREYRARFFSTLETLSMGATPLGMIIVGPTIDKLGYFSVSITLTIVG 381
+++ ++T Q + R S +L++ PLG + G I S+S T + G
Sbjct: 329 IDVALLTLRQRRTDPQQLGRVMSISMSLNLAGFPLGSALAGMVITS----SLSTTFVLAG 384
Query: 382 IA 383
IA
Sbjct: 385 IA 386
>pir||T45097 hypothetical protein [imported] - Mycobacterium smegmatis
>gi|2073532|gb|AAC45274.1| (U46844) orf4; putative
transporter; Method: conceptual translation supplied by
author [Mycobacterium smegmatis]
Length = 412
Score = 76.1 bits (184), Expect = 7e-13
Identities = 74/365 (20%), Positives = 161/365 (43%), Gaps = 21/365 (5%)
Query: 6 RDFWLFAVGRWISIAGWAIQDVAIPLYVLDKTGSGTMMSLFVMAELIPRILVNPIAGVIG 65
RD+ +A+G+ IS++G +Q + VL+ T S ++ + V + +P +L +AGV+
Sbjct: 19 RDYRRYALGQTISVSGTWMQKLTQAWLVLELTDSPLLLGVTVAGQQLPTLLFTTLAGVLA 78
Query: 66 DRYNRKYLMVGFDL---IRGVLLFFVLFFNLLELEQLLVIQVIMSIFGSFFAAGTSGMFP 122
DRY+++ +++ L + ++L +++ +++ + +L V +
Sbjct: 79 DRYSKRTILLWTALGGMLPALVLGVLVWIDVVNIWIVLAAAVAQGFADAVDKPARLTFVN 138
Query: 123 DLVPKDRLMQA---NSILQMGTQVINIVSPVIGGAIYGLGGIKAAIFINAISFFGSGLFE 179
D+ + L A NSI+Q + I P + G + G+ A+ F+NA S+ +
Sbjct: 139 DIATPETLANAVTLNSIIQNSGK---IAGPAVAGVLISAVGVSASFFLNAASYLPVVIAL 195
Query: 180 ISIRYEWKGKGEKFAILREFLDGIKLIKSSKPLLILGSLSIILNALFSPLFAIVFPYIVR 239
+ IR + + ++ + S++P + + + ++ L + + ++ P + R
Sbjct: 196 LLIRPHAPVITGNVSAKGHLGETLRYV-SARPHIAAALVLMAVSGLLAFNWNVLLPTLAR 254
Query: 240 VVLRLSSIQFGSVQTALTLGMLLGNLIIASILKNSAGKHFMKAILIQELFIL--IVPFTP 297
+ G T++ +G + G L +A +L+ ++ + ++ L ++P T
Sbjct: 255 DTFGGDARVVGFAFTSMGVGAVFGGLALAGVLRGTSKWLILNGCVLGAALALTGLMP-TV 313
Query: 298 KLSYPRNYLVILTSAFAIGFFNVLVNIPIMTKLQTIVPREYRARFFSTLETLSMGATPLG 357
++Y F +G +V T LQ R R S L + G TP+G
Sbjct: 314 TIAY--------ALLFVVGAASVTFRSTATTLLQLYSDPGVRGRIISLLVLATNGTTPVG 365
Query: 358 MIIVG 362
++G
Sbjct: 366 GPMIG 370
>emb|CAC11332.1| (AL445063) hypothetical membrane protein [Thermoplasma acidophilum]
Length = 402
Score = 75.7 bits (183), Expect = 9e-13
Identities = 90/395 (22%), Positives = 164/395 (40%), Gaps = 34/395 (8%)
Query: 6 RDFWLFAVGRWISIAGWAIQDVAIPLYVLDKTGSGTMMSLFVMAELIPRILVNPIAGVIG 65
R+F L IS G + ++ I +L TG + L P +L + +
Sbjct: 15 RNFQLTVANAAISRFGLSAYNLVIIWVILQVTGKPALAGLADSMMTFPLMLSIVVGSFVD 74
Query: 66 DRYNRKYLMVGFDLIRGVLLFFVLFFNLLELEQLLVIQVIMSIFGSFFAAG--------- 116
+ +K L + +IR VLL F+LF + + + +SIF + F G
Sbjct: 75 RMWLKKELAISAAVIRVVLLLFILF----AIHTGKDLYIAVSIFAATFILGFTSDVIDSV 130
Query: 117 TSGMFPDLVPKDRLMQANSILQMGTQVINIVSPVIGGAIYGLGGIKAAIFINAISFFGSG 176
S + +D+ +S + T + V ++ G I LG I++ + + I F S
Sbjct: 131 RSSWMKAFLREDQYKAGSSEMSSATMIAQGVGFILSGIIIALGDIRSFLVLTLI-FLISI 189
Query: 177 LFEISIRYEWKGKGEKFAILREFLDGIKLIKSS---KPLLILGSLSIILNALFSPLFAIV 233
L ++IR+ G + I +GIKL + ++I+G ++ + AI+
Sbjct: 190 LPILAIRHARYGGTD--TIQNYIKEGIKLAIGDGRIREVIIIG----LIGNFIVGMAAIM 243
Query: 234 FPYIVRVVLRLSSIQFGSVQTALTLGMLLGNLIIASILKNSAGKHFMKAILIQELFILIV 293
F +V+V RL +I + L G+ +G++ + I N + I I I+ +
Sbjct: 244 FISLVQVGFRLPAIYVSMIFGVLVFGIAIGSVAGSKITGN------VGRISIAMYAIVGI 297
Query: 294 PFTPKLSYPRNYLVILTSAFAIGFFNVLVNIPIMTKLQTIVPREYRARFFSTLETLSMGA 353
F +S +N L+ + +F G + N+ + T L I+P + AR T + A
Sbjct: 298 SFF-SISLVKNALLAVPPSFIAGMAMGIENVAVNTSLMRIIPIDMMARIQGAFNTFGIAA 356
Query: 354 TPLGMIIVGPTIDKLG----YFSVSITLTIVGIAI 384
T + I+ G G + V +++ +V I
Sbjct: 357 TAVSSIVGGFLYQSAGRIYSFMIVGVSMILVSALI 391
>gb|AAD45543.1|U70376_8 (U70376) SpcT [Streptomyces flavopersicus]
Length = 433
Score = 74.5 bits (180), Expect = 2e-12
Identities = 92/388 (23%), Positives = 159/388 (40%), Gaps = 23/388 (5%)
Query: 10 LFAVGRWISIAGWAIQDVAIPLY-VLDKTGSGTMMSLFVMAELIPRILVNPIAGVIGDRY 68
LF ++ G A V +PL VL +L P ++ AG + +R
Sbjct: 30 LFLGSHALNETGAAATLVVLPLTAVLSLDAQAWQTALIQTFHFAPYLVFGLPAGAVVERL 89
Query: 69 NRKYLMVGFDLIRGVLLFFVLF---FNLLELEQLLVIQVIMSIFGSFFAAGTSGMFPDLV 125
+ +M+G DL+R V L + N L L L + +++ F P L+
Sbjct: 90 RPRRVMIGADLLRFVALMSLPVAWALNALSLPHLYAVALLLGGAQLFGDIADQSYLPHLL 149
Query: 126 PKDRLMQANSILQMGTQVINIVSPVIGGAIYGLGGIKAAIFINAISFFGSGLFEISIRY- 184
KDRL Q NS LQM + P IGG G A+ +N ++ S L I
Sbjct: 150 VKDRLFQGNSNLQMIRATAELGGPGIGGVAVQWLGTHLAVAVNGLASALSALLLWRIPVP 209
Query: 185 EWKGKGEKFAILREFLDGIKLIKSSKPLLILGSLSIILNALFSPLFAIVFPYIVRVVLRL 244
+ + ++R+ GI ++ L +L + + N + S A+ ++ +VV +
Sbjct: 210 DAQPAAPSHGLVRQTWHGISVLLRHPVLRLLALSASLNNLILSAALALDVVFLNQVV-GV 268
Query: 245 SSIQFGSVQTALTLGMLLGNLIIASILKN-SAGKHFMKAILIQELFILIVPFTPKLSYPR 303
++ G + A +G L+G + + + +G+ + A+ + F+ ++P T
Sbjct: 269 TAGLVGFLLAAGAVGALIGAWLAPRLTRALGSGRTAVLAVPVAAPFMFLIPLTGD----- 323
Query: 304 NYLVILTSAFAIGFFNVLVNIPI-----MTKLQTIVPREYRARFFSTLETLSMGATPLGM 358
+ V L FA+G + + I + +T Q + P E +R + GA PLG
Sbjct: 324 GWRVAL---FALGHIAISIGITVFNIMQVTYRQQVCPPELLSRMAAMFRWAVWGAAPLGA 380
Query: 359 IIVGPTIDKLGYFSVSITLTIVGIAISV 386
G +G V TL I+ A+ V
Sbjct: 381 TAGGALAASVG---VRDTLWILAGALMV 405
>pir||A83308 probable MFS transporter PA2701 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9948775|gb|AAG06089.1|AE004698_5
(AE004698) probable MFS transporter [Pseudomonas
aeruginosa]
Length = 529
Score = 72.6 bits (175), Expect = 8e-12
Identities = 81/364 (22%), Positives = 153/364 (41%), Gaps = 23/364 (6%)
Query: 9 WLFAVGRWISIAGWAIQDVAIPLYVLDKTGSGTMMSLFVMAELIPRILVNPIAGVIGDRY 68
WL+ +I W + +V + + S ++L +A +P + AG + D
Sbjct: 19 WLWLASIASNIGTW-MHEVGAGWLMTSLSASPLNVALVQVAGSLPMFFLALPAGALADIV 77
Query: 69 NRKYLMVGFDLIRGVLLFFVLFFNLLELEQ---LLVIQVIMSIFGSFFAAGTSGMFPDLV 125
+++ ++G L ++ + LL+L LL + + M I + S P+LV
Sbjct: 78 DKRRYLLGVQLWMALVATLLASLTLLQLTSVWLLLGLTLCMGIGTALMMPAWSATTPELV 137
Query: 126 PKDRLMQANSILQMGTQVINIVSPVIGGAIYGLGGIKAAIFINAISFFGSGLFEISIRYE 185
KD L A ++ +G + V P I G + L G +NA+SFF I++
Sbjct: 138 GKDELPAAVALSSVGVNLARAVGPAIAGVLVSLVGPWLTFALNALSFFA----VIAVLLA 193
Query: 186 WKGKGEKFAILREFLDGI-----KLIKSSKPL--LILGSLSIILNALFSPLFAIVFPYIV 238
WK + + E L G + +SS+PL +++ +++ L A + P IV
Sbjct: 194 WKREAVPSVLPAERLFGALRAGWRYSRSSRPLQSVLVRAVAFFLGASAG---MSLLPLIV 250
Query: 239 RVVLRLSSIQFGSVQTALTLGMLLGNLIIASILKNSAGKHFMKAILIQELFILIVPFTPK 298
R L +++ FG + ++ +G +LG + + + + +L L+ L++
Sbjct: 251 RGELHGNAMDFGLLLGSVGVGAVLGAAFLPRLRERLGSDRLV--LLSSVLYALVL---VA 305
Query: 299 LSYPRNYLVILTSAFAIGFFNVLVNIPIMTKLQTIVPREYRARFFSTLETLSMGATPLGM 358
L+ RN +++ G + V + QT VP RAR + + G+ G
Sbjct: 306 LALLRNLYLLVPVMLLSGAAWIAVLSSLQVAAQTSVPAWVRARALAVYILVFFGSMAAGG 365
Query: 359 IIVG 362
+ G
Sbjct: 366 ALWG 369
>pir||G75408 probable transport protein - Deinococcus radiodurans (strain R1)
>gi|6459076|gb|AAF10896.1|AE001979_2 (AE001979)
transport protein, putative [Deinococcus radiodurans]
Length = 430
Score = 69.9 bits (168), Expect = 5e-11
Identities = 81/416 (19%), Positives = 165/416 (39%), Gaps = 42/416 (10%)
Query: 6 RDFWLFAVGRWISIAGWAIQDVAIPLYVLDKTG-SGTMMSLFVMAELIPRILVNPIAGVI 64
R +W + +S+ G +Q A VL+ +G S ++ +A+ +P +L++ AG +
Sbjct: 22 RRYWF---SQLLSLIGSWMQSTAQQYLVLELSGNSSAALAQVTIAQFLPSLLLSLFAGAV 78
Query: 65 GDRYNRKYLMVGFDLI---RGVLLFFVLFFNLLELEQLLVIQVIMSIFGSFFAAGTSGMF 121
DR R+ +++ + + L + + ++V I I +F M
Sbjct: 79 VDRVPRRRVLLTTQITLMTTAIALAVTTHQGSVSVPLVMVFAFISGIANAFDMPARQTMV 138
Query: 122 PDLVPKDRLMQANSILQMGTQVINIVSPVIGGAIYGLG-------------GIKAAIFIN 168
D VP++++ A ++ + V + + G + LG + ++N
Sbjct: 139 VDFVPREQVSNAVALNSLSFNVSRTIGQALFGVVAALGVSLLAGGNPDSVARLALPFYLN 198
Query: 169 AISFFGSGLFEISIRYEWKGKGEKFAILREFLDGIKLIKSS----KPLLILGSLSI-ILN 223
+SF ++ + + +++ + +G++ +K+ +L++G+LS+ ++N
Sbjct: 199 VVSFLVVLFVIATLPFPPVQERGNHSMVDDVREGLRYVKTHPGVRNVMLLVGALSLTVIN 258
Query: 224 ALFSPLFAIVFPYIVRVVLRLSSIQFGSVQTALTLGMLLGNLIIASILKNSAGKHFMKAI 283
F ++ PY RVV FG + +G + G L AS K + ++
Sbjct: 259 ------FNVIIPYYARVVYGAREATFGLLSAGFGIGAMAGALWQAS--KPNPVRNLRLGA 310
Query: 284 LIQELFILIVPFTPKLSYPRNYLVILTSAFAIGFFNVLVNIPIMTKLQTIVPREYRARFF 343
+ L L + P + + L A GF + I + +Q +P R R
Sbjct: 311 TLVMLSSLALSAVPSAA------LALPVLAACGFGMLTFLISANSTVQLSIPDALRGRVM 364
Query: 344 STLETLSMGATPLGMIIVGPTIDKLGYFSVS---ITLTIVGIAISVYYWLRYSRIL 396
S + +G P G + I + G +TL ++G W R R L
Sbjct: 365 SLYSFVLVGMGPAGAALASTLISREGPLGPRWGLVTLVVLGAIALALLWTRLPREL 420
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.330 0.147 0.429
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 131705607
Number of Sequences: 2977
Number of extensions: 5205089
Number of successful extensions: 19568
Number of sequences better than 1.0e-10: 26
Number of HSP's better than 0.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 19514
Number of HSP's gapped (non-prelim): 28
length of query: 398
length of database: 189,106,746
effective HSP length: 53
effective length of query: 345
effective length of database: 157,386,935
effective search space: 54298492575
effective search space used: 54298492575
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (21.8 bits)
S2: 166 (69.1 bits)