BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB0757 (PAB0757) DE:THYMIDYLATE KINASE related (EC 2.7.4.9) (180 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||H75093 thymidylate kinase related PAB0757 - Pyrococcus abys... 357 4e-98 sp|O58998|YC55_PYRHO HYPOTHETICAL PROTEIN PH1255 >gi|7450212|pir... 320 6e-87 sp|Q58450|YA50_METJA HYPOTHETICAL PROTEIN MJ1050 >gi|2128644|pir... 142 3e-33 gi|11499583 conserved hypothetical protein [Archaeoglobus fulgid... 133 1e-30 sp|O27656|YG19_METTH HYPOTHETICAL PROTEIN MTH1619 >gi|7450210|pi... 109 3e-23 gi|6320035 Ydl166cp [Saccharomyces cerevisiae] >gi|6831740|sp|Q1... 90 1e-17 gb|AAF09498.1| (AF195950) unknown protein [Oryctolagus sp.] 90 1e-17 gb|AAK40785.1| Conserved hypothetical protein [Sulfolobus solfat... 90 1e-17 gb|AAG19442.1| (AE005037) Vng1031c [Halobacterium sp. NRC-1] 89 4e-17 gi|7706212 adrenal gland protein AD-004 [Homo sapiens] >gi|68317... 88 7e-17 pir||T41637 conserved hypothetical protein SPCC830.11c - fission... 78 8e-14 emb|CAC11710.1| (AL445064) conserved hypothetical protein [Therm... 77 1e-13 dbj|BAB10972.1| (AB015471) gene_id:K9B18.5~ref|NP_057367.1~simil... 75 4e-13 >pir||H75093 thymidylate kinase related PAB0757 - Pyrococcus abyssi (strain Orsay) >gi|5458565|emb|CAB50053.1| (AJ248286) THYMIDYLATE KINASE related (EC 2.7.4.9) [Pyrococcus abyssi] Length = 180 Score = 357 bits (907), Expect = 4e-98 Identities = 180/180 (100%), Positives = 180/180 (100%) Query: 1 MLIAITGTPGVGKTTIAKLLAEKLGYEYVNLRDFALEKGCGREVDGEVEVEIDELAYFVE 60 MLIAITGTPGVGKTTIAKLLAEKLGYEYVNLRDFALEKGCGREVDGEVEVEIDELAYFVE Sbjct: 1 MLIAITGTPGVGKTTIAKLLAEKLGYEYVNLRDFALEKGCGREVDGEVEVEIDELAYFVE 60 Query: 61 KELKDRNVVLDGHLSHLMPVDLVVVLRAHPRIIGERLRERGYSKEKIGENVEAELVDAIL 120 KELKDRNVVLDGHLSHLMPVDLVVVLRAHPRIIGERLRERGYSKEKIGENVEAELVDAIL Sbjct: 61 KELKDRNVVLDGHLSHLMPVDLVVVLRAHPRIIGERLRERGYSKEKIGENVEAELVDAIL 120 Query: 121 IEAIDEHENVIEVDTTNKTPEEIVEEIIGLIKSGVKRRVGIVDWSEVYDEIIPYLRLGGE 180 IEAIDEHENVIEVDTTNKTPEEIVEEIIGLIKSGVKRRVGIVDWSEVYDEIIPYLRLGGE Sbjct: 121 IEAIDEHENVIEVDTTNKTPEEIVEEIIGLIKSGVKRRVGIVDWSEVYDEIIPYLRLGGE 180 >sp|O58998|YC55_PYRHO HYPOTHETICAL PROTEIN PH1255 >gi|7450212|pir||B71070 hypothetical protein PH1255 - Pyrococcus horikoshii >gi|3257673|dbj|BAA30356.1| (AP000005) 180aa long hypothetical protein [Pyrococcus horikoshii] Length = 180 Score = 320 bits (812), Expect = 6e-87 Identities = 153/180 (85%), Positives = 172/180 (95%) Query: 1 MLIAITGTPGVGKTTIAKLLAEKLGYEYVNLRDFALEKGCGREVDGEVEVEIDELAYFVE 60 MLIAITGTPGVGKTT+AKLLA+KL YEYV+L+DFALEKGCGR V+ EVEVEIDELAYF+E Sbjct: 1 MLIAITGTPGVGKTTVAKLLAKKLNYEYVSLKDFALEKGCGRRVNDEVEVEIDELAYFIE 60 Query: 61 KELKDRNVVLDGHLSHLMPVDLVVVLRAHPRIIGERLRERGYSKEKIGENVEAELVDAIL 120 +ELK +N VLDGHLSHLMPVDLVVVLRAHP++IGERLRERGY +EKIGENVEAELVDA+L Sbjct: 61 RELKGKNAVLDGHLSHLMPVDLVVVLRAHPKLIGERLRERGYDREKIGENVEAELVDAVL 120 Query: 121 IEAIDEHENVIEVDTTNKTPEEIVEEIIGLIKSGVKRRVGIVDWSEVYDEIIPYLRLGGE 180 IEAI+EHENVIEVDTTNK+PE++VEEI+ LI SG+K+RVGIVDWSEVYDEIIPYLRLGGE Sbjct: 121 IEAIEEHENVIEVDTTNKSPEDVVEEIVSLINSGIKKRVGIVDWSEVYDEIIPYLRLGGE 180 >sp|Q58450|YA50_METJA HYPOTHETICAL PROTEIN MJ1050 >gi|2128644|pir||A64431 hypothetical protein MJ1050 - Methanococcus jannaschii >gi|1499895|gb|AAB99053.1| (U67548) conserved hypothetical protein [Methanococcus jannaschii] Length = 177 Score = 142 bits (354), Expect = 3e-33 Identities = 75/172 (43%), Positives = 117/172 (67%), Gaps = 8/172 (4%) Query: 1 MLIAITGTPGVGKTTIAKLLAEKLGYEYVNLRDFALEKGCGREVDGEVE---VEIDELAY 57 M IAITGTPGVGKTTI+K+L ++LG + +++ + + E D +++ ++ ++L Sbjct: 1 MRIAITGTPGVGKTTISKVLRDRLGIKVIDITEAVKKYKLYTEKDEDMDSYVIDFEKLEK 60 Query: 58 FVEK-ELKDRNVVLDGHLSHLMPVDLVVVLRAHPRIIGERLRERGYSKEKIGENVEAELV 116 F+++ E K++ ++LDGH+SHL+ D ++VLR +P II ERL +RGY +K+ EN++AE++ Sbjct: 61 FIDEIEEKEKTIILDGHVSHLLNPDYIIVLRCNPEIIKERLEKRGYKPKKVLENIQAEIL 120 Query: 117 DAILIEAIDEHENVIEVDTTNKTPEEIVEEIIGLIKSGVKRRVGIVDWSEVY 168 D L E+ V E+DTTN+ E IV+EII IK K R G+VDW+E Y Sbjct: 121 DVCLCES---KGKVYEIDTTNRDVENIVDEIIEAIKH-KKERKGVVDWTEKY 168 >gi|11499583 conserved hypothetical protein [Archaeoglobus fulgidus] >gi|3123135|sp|O28278|YK01_ARCFU HYPOTHETICAL PROTEIN AF2001 >gi|7450209|pir||H69499 conserved hypothetical protein AF2001 - Archaeoglobus fulgidus >gi|2648537|gb|AAB89254.1| (AE000964) conserved hypothetical protein [Archaeoglobus fulgidus] Length = 178 Score = 133 bits (331), Expect = 1e-30 Identities = 72/182 (39%), Positives = 120/182 (65%), Gaps = 12/182 (6%) Query: 1 MLIAITGTPGVGKTTIAKLLAEKLGYEYVNLRDFALEKGCG-REVDGEVEVEIDELAYFV 59 MLIA+TGTPG GK+++A+ L E+ GY+ + + A + GC E DGE+ ++++ LA + Sbjct: 1 MLIALTGTPGTGKSSVAERLRER-GYKVATVVELAEKHGCIIDEEDGEIVIDVESLAARI 59 Query: 60 EKELKDRNVVLDGHLSHLMPVDLVVVLRAHPRIIGERLRERGYSKEKIGENVEAELVDAI 119 + E +++GHLSHL+ D+ +VLR +P ++ ERL+ R +S+EK+ EN+EAE++D I Sbjct: 60 DFE-----GIVEGHLSHLLKPDVAIVLRCNPAVLRERLKGRNWSEEKLLENLEAEMLDVI 114 Query: 120 LIEAIDEHENVIEVDTTNKTPEEIVEEIIGLIKSGVKRR----VGIVDW-SEVYDEIIPY 174 L+EA++ V E+DTT + EE++E + +I+ + R G +DW SE+ D I + Sbjct: 115 LVEALEHASEVYEIDTTEMSLEEVIEAVEAIIRGDREARKRYKPGGIDWLSELEDRIEEF 174 Query: 175 LR 176 +R Sbjct: 175 MR 176 >sp|O27656|YG19_METTH HYPOTHETICAL PROTEIN MTH1619 >gi|7450210|pir||C69083 conserved hypothetical protein MTH1619 - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622745|gb|AAB86092.1| (AE000921) conserved protein (adenylate kinase related) [Methanobacterium thermoautotrophicum] Length = 171 Score = 109 bits (269), Expect = 3e-23 Identities = 69/169 (40%), Positives = 105/169 (61%), Gaps = 8/169 (4%) Query: 2 LIAITGTPGVGKTTIAKLLAEKLGYEYVNLRDFALEKG--CGRE-VDGEVEVEIDELAYF 58 +I ITGTPGVGKTT+A +L E+ G E ++L + +KG GR+ + G +E +I+ Sbjct: 1 MICITGTPGVGKTTLAGILRER-GLEVISLGELIRQKGFVLGRDPIRGYLEADIEAACSH 59 Query: 59 VEKELKDRNVVLDGHLSHLM-PVDLVVVLRAHPRIIGERLRERGYSKEKIGENVEAELVD 117 ++ E++ +VV +GHLSHL +V+VLR HP ++ RL RGY + K+ EN+EAE +D Sbjct: 60 LQ-EMEGLDVV-EGHLSHLCRSCSMVIVLRLHPEVLRGRLEGRGYPEGKVLENLEAEALD 117 Query: 118 AILIEAIDEH-ENVIEVDTTNKTPEEIVEEIIGLIKSGVKRRVGIVDWS 165 +EA + H E V EVDTT ++P E+ + I ++ G VD+S Sbjct: 118 VCTVEAFEIHGERVHEVDTTGRSPHEVADIITDIMNGSRVCPPGGVDFS 166 >gi|6320035 Ydl166cp [Saccharomyces cerevisiae] >gi|6831740|sp|Q12055|YDB6_YEAST HYPOTHETICAL 22.7 KDA PROTEIN IN CDC36-NRP1 INTERGENIC REGION >gi|2131352|pir||S61047 hypothetical protein YDL166c - yeast (Saccharomyces cerevisiae) >gi|1061273|emb|CAA91580.1| (Z67750) putative protein [Saccharomyces cerevisiae] >gi|1431264|emb|CAA98740.1| (Z74214) ORF YDL166c [Saccharomyces cerevisiae] Length = 197 Score = 90.5 bits (221), Expect = 1e-17 Identities = 53/156 (33%), Positives = 88/156 (55%), Gaps = 7/156 (4%) Query: 3 IAITGTPGVGKTTIAKLLAEKL-GYEYVNLRDFALEKGCGREVDGEVE---VEIDELAYF 58 I +TGTPG GK++ + L KL Y+Y N+ DFA + C D + V+ D+L Sbjct: 10 IIVTGTPGCGKSSTCEFLKNKLKDYKYYNISDFAKDNDCFEGYDEGRKSHIVDEDKLLDM 69 Query: 59 VEKELKDRNVVLDGHLSHLMP---VDLVVVLRAHPRIIGERLRERGYSKEKIGENVEAEL 115 +E L+ N ++D H++ + P +DLVVVLR + RL RGY KI EN++AE+ Sbjct: 70 LEPLLRQGNSIVDWHVNDVFPERLIDLVVVLRCDNSNLYSRLHARGYHDSKIEENLDAEI 129 Query: 116 VDAILIEAIDEHENVIEVDTTNKTPEEIVEEIIGLI 151 + + +A++ +E I V+ + T E++V + ++ Sbjct: 130 MGVVKQDAVESYEPHIVVELQSDTKEDMVSNVSRIV 165 >gb|AAF09498.1| (AF195950) unknown protein [Oryctolagus sp.] Length = 172 Score = 90.5 bits (221), Expect = 1e-17 Identities = 52/156 (33%), Positives = 85/156 (54%), Gaps = 6/156 (3%) Query: 3 IAITGTPGVGKTTIAKLLAEKLGYEYVNLRDFALEKGCGREVDGEVEVEI---DELAYFV 59 I +TGTPGVGKTT+ K LA + G +YVN+ D A E D E I D + + Sbjct: 6 ILLTGTPGVGKTTLGKELASRSGLKYVNVGDLAREGELYDGFDEEYNCPILDEDRVIDEL 65 Query: 60 EKELKDRNVVLDGHLSHLMP---VDLVVVLRAHPRIIGERLRERGYSKEKIGENVEAELV 116 + +++D V++D H P +V VLR ++ +RL RGYS++K+ +N++ E+ Sbjct: 66 DTQMRDGGVIVDYHGCDFFPERWFHIVFVLRTETSVLYKRLETRGYSEKKLNDNIQCEIF 125 Query: 117 DAILIEAIDEHENVIEVDTTNKTPEEIVEEIIGLIK 152 + EA++ ++ I + PEE+ E I ++K Sbjct: 126 QVLYEEAMESYKEEIVHQLPSNKPEELEENISQILK 161 >gb|AAK40785.1| Conserved hypothetical protein [Sulfolobus solfataricus] Length = 187 Score = 90.1 bits (220), Expect = 1e-17 Identities = 59/169 (34%), Positives = 96/169 (55%), Gaps = 11/169 (6%) Query: 1 MLIAITGTPGVGKTTIAKLLAEKLGYEYVNLRDFALEKGCGREVD---GEVEVEIDELAY 57 M+I +TGTPGVGKT +K L+E L Y++L F +E E D ++ D++ Sbjct: 1 MIIIVTGTPGVGKTVASKKLSEALNLNYLSLSQFVIENKLYTEYDELRQSYIIDEDKVKE 60 Query: 58 FVEKELKDRNVVLDG-HLSHLMPVDLVVVLRAHPRIIGERLRERGYSKEKIGENVEAELV 116 +EK + ++V++ + S + DLVVVLR +P + L+ RG++ K+ ENVEAE++ Sbjct: 61 ELEKIISTSHLVIETIYPSLVSTADLVVVLRKNPFSLYNELKGRGWADIKVAENVEAEIL 120 Query: 117 DAILIEAIDE-HENVIEVDTTNKTPEEIVEEIIGLIKSGVKRRVGIVDW 164 I EA + + V EVDTT + E+I+ +I+ K+ G ++W Sbjct: 121 GVISQEAREAFKDKVCEVDTTEMSTEQILNKILN------KQCDGPIEW 163 >gb|AAG19442.1| (AE005037) Vng1031c [Halobacterium sp. NRC-1] Length = 169 Score = 88.5 bits (216), Expect = 4e-17 Identities = 60/173 (34%), Positives = 96/173 (54%), Gaps = 13/173 (7%) Query: 1 MLIAITGTPGVGKTTIAKLLAEKLGYEYVNLRDFALEKGCGREVD---GEVEVEIDELA- 56 M +A+TGTPG GKTT L L ++N D +G VD G V++D + Sbjct: 1 MRVAVTGTPGTGKTTATGRLDTALDVAHLN--DLVGTEGLYDGVDADRGSKIVDVDAVRD 58 Query: 57 YFVEKELKDRNVVLDGHLSH-LMPVDLVVVLRAHPRIIGERLRERGYSKEKIGENVEAEL 115 +F +E +V+++ HL+H L +D VVVLR P + RL++RG S EK EN ++E Sbjct: 59 HFAGRE----DVLVESHLAHRLDDLDAVVVLRCAPETLATRLQDRGDSPEKAAENADSEA 114 Query: 116 VDAILIEAIDEH--ENVIEVDTTNKTPEEIVEEIIGLIKSGVKRRVGIVDWSE 166 + IL EA+ H + V E+DTT+++P+ + I ++ + G VD+++ Sbjct: 115 LAIILSEAVRGHGADAVYEIDTTDRSPDAVAAAIQAVLDGDREPSAGTVDYTD 167 >gi|7706212 adrenal gland protein AD-004 [Homo sapiens] >gi|6831735|sp|Q9Y3D8|AD04_HUMAN ADRENAL GLAND PROTEIN AD-004 (CGI-137) >gi|4929743|gb|AAD34132.1|AF151895_1 (AF151895) CGI-137 protein [Homo sapiens] >gi|6523801|gb|AAF14860.1|AF110777_1 (AF110777) adrenal gland protein AD-004 [Homo sapiens] Length = 172 Score = 87.8 bits (214), Expect = 7e-17 Identities = 52/163 (31%), Positives = 89/163 (53%), Gaps = 9/163 (5%) Query: 3 IAITGTPGVGKTTIAKLLAEKLGYEYVNLRDFALEKGCGREVDGEVEVEI---DELAYFV 59 I +TGTPGVGKTT+ K LA K G +Y+N+ D A E+ D E + I D + + Sbjct: 6 ILLTGTPGVGKTTLGKELASKSGLKYINVGDLAREEQLYDGYDEEYDCPILDEDRVVDEL 65 Query: 60 EKELKDRNVVLDGHLSHLMP---VDLVVVLRAHPRIIGERLRERGYSKEKIGENVEAELV 116 + ++++ V++D H P +V VLR ++ ERL RGY+++K+ +N++ E+ Sbjct: 66 DNQMREGGVIVDYHGCDFFPERWFHIVFVLRTDTNVLYERLETRGYNEKKLTDNIQCEIF 125 Query: 117 DAILIEAIDEHENVIEVDTTNKTPEEI---VEEIIGLIKSGVK 156 + EA ++ I + PEE+ V++I+ I+ +K Sbjct: 126 QVLYEEATASYKEEIVHQLPSNKPEELENNVDQILKWIEQWIK 168 >pir||T41637 conserved hypothetical protein SPCC830.11c - fission yeast (Schizosaccharomyces pombe) >gi|5738876|emb|CAB52884.1| (AL109850) conserved hypothetical protein [Schizosaccharomyces pombe] Length = 175 Score = 77.6 bits (188), Expect = 8e-14 Identities = 53/147 (36%), Positives = 79/147 (53%), Gaps = 6/147 (4%) Query: 3 IAITGTPGVGKTTIAKLLAEKLGYEYVNLRDFALEKGCGREVDGE---VEVEIDELAYFV 59 I I GTPG GKTT+A+ +AE E + + D E D + +V+ D++ ++ Sbjct: 11 IIICGTPGTGKTTLAEQVAETTELENICIGDVVKENHLHFGFDEKWKTYDVDEDKVLDYL 70 Query: 60 EKELKDRNVVLDGHLSHLMP---VDLVVVLRAHPRIIGERLRERGYSKEKIGENVEAELV 116 E +L ++D H L +DLVVVLR + ERL RGYS EKI EN EAE++ Sbjct: 71 EPKLLKGGCIIDWHTCGLFSEELIDLVVVLRTDHSKLWERLESRGYSLEKIQENNEAEIM 130 Query: 117 DAILIEAIDEHENVIEVDTTNKTPEEI 143 L EA + + I V+ +++ EE+ Sbjct: 131 QICLEEARESFDPKIVVELPSESIEEM 157 >emb|CAC11710.1| (AL445064) conserved hypothetical protein [Thermoplasma acidophilum] Length = 166 Score = 77.3 bits (187), Expect = 1e-13 Identities = 45/124 (36%), Positives = 76/124 (61%), Gaps = 7/124 (5%) Query: 2 LIAITGTPGVGKTTIAKLLAEKLGYEYVNLRDFALEKGCGREVDGEVEVEIDELAYFVEK 61 LI I+G PG GK+TI LL + LGY V A++ GC + G+ EV++D L+ + Sbjct: 19 LICISGIPGTGKSTICNLLND-LGYTCVEGNALAVKYGC---LSGD-EVDVDCLSDRMRS 73 Query: 62 ELKDRNVVLDGHLSHLMPVDLVVVLRAHPRIIGERLRERGYSKEKIGENVEAELVDAILI 121 + + ++ H +HL+P ++V++L A + +R+ +RGYS EKI EN++A+ D I Sbjct: 74 D--NFKGIVAAHYAHLLPCNIVIILEADESALRQRMMDRGYSPEKIDENLDAQRSDTIYA 131 Query: 122 EAID 125 E+++ Sbjct: 132 ESLE 135 >dbj|BAB10972.1| (AB015471) gene_id:K9B18.5~ref|NP_057367.1~similar to unknown protein [Arabidopsis thaliana] Length = 178 Score = 75.3 bits (182), Expect = 4e-13 Identities = 47/151 (31%), Positives = 74/151 (48%), Gaps = 6/151 (3%) Query: 3 IAITGTPGVGKTTIAKLLAEKLGYEYVNLRDFALEKGCGREVDGEVE---VEIDELAYFV 59 + ITGTPG GK+T A LAE Y+ + D EK D E+E + D + + Sbjct: 16 LLITGTPGTGKSTTASALAEATNLRYICIGDLVKEKEFYHGWDNELECHFINEDSVIDEL 75 Query: 60 EKELKDRNVVLDGHLSHLMP---VDLVVVLRAHPRIIGERLRERGYSKEKIGENVEAELV 116 + + + ++D H P D VVVLR ++ +RL RGYS K+ N++ E+ Sbjct: 76 DDAMIEGGNIVDYHGCDFFPQRWFDRVVVLRTENSVLYDRLTNRGYSGTKLSNNLQCEMY 135 Query: 117 DAILIEAIDEHENVIEVDTTNKTPEEIVEEI 147 +L EA D ++ I + + T E+I + Sbjct: 136 QVLLEEAHDSYDEEIVTELQSNTIEDISNNV 166 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.317 0.141 0.392 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 68765790 Number of Sequences: 2977 Number of extensions: 2963857 Number of successful extensions: 14069 Number of sequences better than 1.0e-10: 13 Number of HSP's better than 0.0 without gapping: 4 Number of HSP's successfully gapped in prelim test: 9 Number of HSP's that attempted gapping in prelim test: 14044 Number of HSP's gapped (non-prelim): 14 length of query: 180 length of database: 189,106,746 effective HSP length: 55 effective length of query: 125 effective length of database: 156,189,961 effective search space: 19523745125 effective search space used: 19523745125 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.5 bits) S2: 162 (67.5 bits)