BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB0761 (PAB0761) DE:TRANSPORT PROTEIN, permease
         (372 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||D75094 transport protein, permease PAB0761 - Pyrococcus aby...   715  0.0
pir||H71070 hypothetical protein PH1260 - Pyrococcus horikoshii ...   618  e-176
sp|O34456|EXUT_BACSU HEXURONATE TRANSPORTER >gi|7428807|pir||A69...   130  3e-29
pir||D71144 hypothetical protein PH0367 - Pyrococcus horikoshii ...   116  5e-25
gb|AAG28456.1|AF195244_3 (AF195244) putative transporter [Pyroco...   111  1e-23
gb|AAD46810.1|AF157643_4 (AF157643) putative transporter protein...   107  2e-22
gb|AAK41360.1| Transport membrane protein (permease) [Sulfolobus...   106  6e-22
emb|CAC12461.1| (AL445067) transport membrane protein (permease)...   104  2e-21
pir||A83133 probable MFS transporter PA4096 [imported] - Pseudom...   104  2e-21
gb|AAG20513.1| (AE005123) D-lactate dehydrogenase; Dld [Halobact...   104  2e-21
pir||T44249 transport protein homolog [imported] - Arthrobacter ...   104  2e-21
gi|11498512 conserved hypothetical protein [Archaeoglobus fulgid...   101  1e-20
pir||D71112 hypothetical protein PH0667 - Pyrococcus horikoshii ...    99  1e-19
sp|P31457|DGOT_ECOLI D-GALACTONATE TRANSPORTER                         95  1e-18
pir||D65171 hypothetical 48.8 kD protein in ibpA-gyrB intergenic...    95  1e-18
gb|AAD10060.1| (AF113952) multidrug-efflux transporter [Campylob...    95  1e-18
pir||D81282 probable efflux protein Cj1375 [imported] - Campylob...    95  1e-18
pir||E75048 multidrug resistance protein PAB0913 - Pyrococcus ab...    94  2e-18
pir||D83160 nitrite extrusion protein 1 PA3877 [imported] - Pseu...    90  3e-17
pir||F83064 probable MFS transporter PA4654 [imported] - Pseudom...    90  5e-17
pir||S74046 probable sugar transport protein c0110 - Sulfolobus ...    90  5e-17
gb|AAK42313.1| Sugar transport related protein [Sulfolobus solfa...    90  5e-17
pir||A83383 probable MFS transporter PA2114 [imported] - Pseudom...    89  6e-17
pir||F71713 glycerol-3-phosphate transporter (glpT) RP054 - Rick...    88  2e-16
pir||T46710 multidrug resistance transporter [imported] - Lister...    87  2e-16
pir||G71118 hypothetical protein PH0718 - Pyrococcus horikoshii ...    87  2e-16
sp|P94131|MUCK_ACICA CIS,CIS-MUCONATE TRANSPORT PROTEIN >gi|1842...    86  6e-16
pir||E75042 transporter (major facilitator family) related PAB08...    86  7e-16
pir||S56504 hypothetical 46.6K protein (leuX-fecE intergenic reg...    85  1e-15
sp|P39352|YJHB_ECOLI HYPOTHETICAL METABOLITE TRANSPORT PROTEIN I...    85  1e-15
pir||D83518 cis,cis-muconate transporter MucK PA1019 [imported] ...    85  2e-15
gi|11497979 oxalate/formate antiporter (oxlT-2) [Archaeoglobus f...    85  2e-15
dbj|BAB05122.1| (AP001511) multidrug resistance protein [Bacillu...    85  2e-15
sp|P27669|UHPC_SALTY REGULATORY PROTEIN UHPC >gi|421217|pir||C41...    84  2e-15
gb|AAB48105.1| (U41818) PhlE [Pseudomonas fluorescens]                 84  3e-15
pir||G64494 quinolone resistance protein norA homolog - Methanoc...    84  3e-15
sp|O51798|MMLH_ALCEU PROBABLE 4-METHYLMUCONOLACTONE TRANSPORTER ...    84  3e-15
sp|P39637|YWFA_BACSU HYPOTHETICAL 44.5 KD PROTEIN IN ROCC-PTA IN...    83  5e-15
sp|P42609|EXUT_ECOLI HEXURONATE TRANSPORTER >gi|7428805|pir||B65...    83  6e-15
sp|P42613|GARP_ECOLI PROBABLE GALACTARATE TRANSPORTER (D-GALACTA...    83  6e-15
gb|AAA57897.1| (U18997) ORF_o472 [Escherichia coli]                    82  8e-15
pir||B83017 probable MFS transporter PA5030 [imported] - Pseudom...    81  2e-14
gi|11498923 multidrug resistance protein [Archaeoglobus fulgidus...    80  3e-14
pir||T47026 hypothetical protein [imported] - Yersinia pestis >g...    80  3e-14
sp|P39398|YJJL_ECOLI HYPOTHETICAL 49.4 KD PROTEIN IN TSR-MDOB IN...    80  3e-14
pir||D75358 probable fosmidomycin resistance protein - Deinococc...    80  4e-14
pir||D72302 hypothetical protein TM1021 - Thermotoga maritima (s...    80  5e-14
gb|AAF58060.1| (AE003808) CG8428 gene product [Drosophila melano...    80  5e-14
gb|AAK41596.1| Transport membrane protein (permease) [Sulfolobus...    79  7e-14
sp|P37948|GLPT_BACSU GLYCEROL-3-PHOSPHATE TRANSPORTER (G-3-P TRA...    78  1e-13
sp|P46907|NARK_BACSU NITRITE EXTRUSION PROTEIN (NITRITE FACILITA...    78  1e-13
dbj|BAB13277.1| (AP001119) hypothetical protein [Buchnera sp. APS]     78  2e-13
gb|AAA16158.1| (M80252) norA1199 protein [Staphylococcus aureus]...    78  2e-13
sp|Q46916|GUDP_ECOLI PROBABLE GLUCARATE TRANSPORTER (D-GLUCARATE...    78  2e-13
pir||A64668 chloramphenicol resistance protein homolog HP1185 - ...    77  3e-13
emb|CAC13963.1| (AJ012115) multidrug efflux transporter [Listeri...    77  3e-13
gb|AAG34371.1|AF197465_3 (AF197465) putative nitrate/nitrite tra...    77  3e-13
dbj|BAA36484.1| (AB019536) NorA [Staphylococcus aureus]                77  4e-13
emb|CAB76354.1| (AL158061) putative transmembrane transport prot...    77  4e-13
gb|AAK42961.1| Proline/betaine transporter, putative [Sulfolobus...    76  5e-13
gi|11498744 multidrug resistance protein [Archaeoglobus fulgidus...    76  5e-13
emb|CAA07482.1| (AJ007367) multi-drug resistance efflux pump [St...    76  5e-13
emb|CAB61680.1| (AL133213) putative transmembrane transport prot...    76  5e-13
pir||F69814 fosmidmycin resistance protein homolog yfnC - Bacill...    76  6e-13
gb|AAB31949.1| (S74031) NorA {ISP794, quinolone resistance} [Sta...    76  6e-13
sp|P21191|NORA_STAAU QUINOLONE RESISTANCE NORA PROTEIN >gi|97835...    76  8e-13
pir||D83117 probable MFS transporter PA4233 [imported] - Pseudom...    76  8e-13
pir||B82991 glycerol-3-phosphate transporter PA5235 [imported] -...    76  8e-13
sp|P42237|GUDP_BACSU PROBABLE GLUCARATE TRANSPORTER (D-GLUCARATE...    75  2e-12
pir||F83233 probable MFS transporter PA3303 [imported] - Pseudom...    75  2e-12
pir||H71846 hypothetical protein jhp1111 - Helicobacter pylori (...    74  2e-12
gb|AAG23889.1| (AY008833) TcaB [Staphylococcus aureus]                 74  2e-12
gb|AAK42828.1| Permease [Sulfolobus solfataricus]                      73  4e-12
sp|O34691|YCEI_BACSU HYPOTHETICAL METABOLITE TRANSPORT PROTEIN I...    73  4e-12
sp|Q43975|PCAK_ACICA 4-HYDROXYBENZOATE TRANSPORTER >gi|3172116|g...    73  4e-12
pir||S56583 hypothetical protein f261b - Escherichia coli >gi|53...    73  5e-12
pir||E69783 bicyclomycin resistance protein homolog ydgK - Bacil...    73  5e-12
dbj|BAB04893.1| (AP001511) multidrug-efflux transporter [Bacillu...    73  5e-12
gb|AAK41760.1| Transport protein [Sulfolobus solfataricus]             73  7e-12
gb|AAC45758.1| (U40014) nitrate transporter [Staphylococcus carn...    73  7e-12
gi|11499136 conserved hypothetical protein [Archaeoglobus fulgid...    72  1e-11
pir||E83385 hypothetical protein PA2091 [imported] - Pseudomonas...    72  1e-11
dbj|BAB06030.1| (AP001515) unknown conserved protein [Bacillus h...    72  1e-11
emb|CAC08554.1| (AL121673) bA305P22.2 (novel protein) [Homo sapi...    72  1e-11
sp|P44535|YDEA_HAEIN HYPOTHETICAL PROTEIN HI0135 >gi|1074278|pir...    71  2e-11
gb|AAC15508.1| (L49465) hypothetical metabolite transport protei...    71  2e-11
pir||F71848 probable transporter - Helicobacter pylori (strain J...    71  2e-11
pir||B83180 probable MFS transporter PA3718 [imported] - Pseudom...    71  2e-11
dbj|BAB07028.1| (AP001518) multidrug resistance protein [Bacillu...    71  2e-11
gb|AAB81315.1| (U89712) putative 3-(3-hydroxyphenyl) propionate ...    71  2e-11
pir||E64667 multidrug-efflux transporter - Helicobacter pylori (...    71  2e-11
emb|CAB93456.1| (AL357591) putative integral membrane transport ...    71  2e-11
emb|CAB71269.1| (AL138598) putative integral membrane efflux pro...    71  3e-11
pir||E81862 probable integral membrane transporter NMA1673 [impo...    71  3e-11
gb|AAG19033.1| (AE005003) multidrug resistance protein homolog; ...    71  3e-11
sp|Q51955|PCAK_PSEPU 4-HYDROXYBENZOATE TRANSPORTER >gi|1147822|g...    70  4e-11
gb|AAK42225.1| Metabolite transport protein [Sulfolobus solfatar...    70  4e-11
pir||S74875 quinolone resistance protein norA - Synechocystis sp...    70  4e-11
gb|AAB70881.1| (U86689) exuT [Pectobacterium chrysanthemi]             70  4e-11
gb|AAK41393.1| Transport protein, permease [Sulfolobus solfatari...    70  5e-11
sp|P13924|TCR_STRAG TETRACYCLINE RESISTANCE PROTEIN >gi|581578|e...    70  5e-11
pir||T37042 probable nitrate/nitrite transport protein - Strepto...    70  5e-11
pir||B81080 drug resistance translocase family protein NMB1461 [...    69  6e-11
pir||G83322 hypothetical protein PA2589 [imported] - Pseudomonas...    69  6e-11
pir||F82177 probable multidrug resistance protein VC1618 [import...    69  8e-11

>pir||D75094 transport protein, permease PAB0761 - Pyrococcus abyssi  (strain
           Orsay) >gi|5458569|emb|CAB50057.1| (AJ248286) TRANSPORT
           PROTEIN, permease [Pyrococcus abyssi]
           Length = 372
           
 Score =  715 bits (1826), Expect = 0.0
 Identities = 372/372 (100%), Positives = 372/372 (100%)

Query: 1   MEKLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPA 60
           MEKLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPA
Sbjct: 1   MEKLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPA 60

Query: 61  GYIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISE 120
           GYIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISE
Sbjct: 61  GYIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISE 120

Query: 121 LFRERKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIK 180
           LFRERKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIK
Sbjct: 121 LFRERKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIK 180

Query: 181 GEPIKVEGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYLVSRGVGMEKASLMFSMLS 240
           GEPIKVEGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYLVSRGVGMEKASLMFSMLS
Sbjct: 181 GEPIKVEGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYLVSRGVGMEKASLMFSMLS 240

Query: 241 LVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSVGGIMT 300
           LVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSVGGIMT
Sbjct: 241 LVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSVGGIMT 300

Query: 301 AYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVI 360
           AYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVI
Sbjct: 301 AYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVI 360

Query: 361 IGLDLRKTSYKG 372
           IGLDLRKTSYKG
Sbjct: 361 IGLDLRKTSYKG 372


>pir||H71070 hypothetical protein PH1260 - Pyrococcus horikoshii
           >gi|3257679|dbj|BAA30362.1| (AP000005) 372aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 372
           
 Score =  618 bits (1577), Expect = e-176
 Identities = 307/371 (82%), Positives = 346/371 (92%)

Query: 1   MEKLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPA 60
           M+KLIILILISLGWIFNYSHRMAVPSLAPI+MK+L INN E+GLLMT+LLLPYSLIQVPA
Sbjct: 1   MQKLIILILISLGWIFNYSHRMAVPSLAPILMKELSINNTEVGLLMTALLLPYSLIQVPA 60

Query: 61  GYIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISE 120
           GYIGDKIGRKKLLT+SILGYS+SSALIVL R+YWDLV +RALYGFFAGLYYAPAT+LISE
Sbjct: 61  GYIGDKIGRKKLLTLSILGYSISSALIVLARNYWDLVAIRALYGFFAGLYYAPATSLISE 120

Query: 121 LFRERKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIK 180
           LFRE+KGSALGFFM+GPAIGSGITPLIVVPVAL L+WR +FLVLSIMSSIVG+LL++ +K
Sbjct: 121 LFREKKGSALGFFMIGPAIGSGITPLIVVPVALMLNWRLSFLVLSIMSSIVGVLLVLTVK 180

Query: 181 GEPIKVEGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYLVSRGVGMEKASLMFSMLS 240
           GEP++VE  KF IP+GV LLSLANFLGLGAFFAMLTFLVSYLVS+GV +++ASLMFS+LS
Sbjct: 181 GEPVEVERAKFSIPKGVLLLSLANFLGLGAFFAMLTFLVSYLVSKGVDIKEASLMFSILS 240

Query: 241 LVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSVGGIMT 300
           LVG+ GS+ AGFLYD+ GKVSV LAY LN LLTFL+IV P+PL LIPLGLVLYSVGGI+T
Sbjct: 241 LVGVFGSVTAGFLYDYAGKVSVFLAYLLNFLLTFLIIVFPTPLLLIPLGLVLYSVGGIIT 300

Query: 301 AYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVI 360
           AYT+EKA + NLGVVMGFVNMVGFFGAT GPY+VGFLID+LGYS ALLSVPLAYLVSA+I
Sbjct: 301 AYTAEKAEKSNLGVVMGFVNMVGFFGATTGPYVVGFLIDKLGYSRALLSVPLAYLVSALI 360

Query: 361 IGLDLRKTSYK 371
           I +D+RKTSYK
Sbjct: 361 IIVDIRKTSYK 371


>sp|O34456|EXUT_BACSU HEXURONATE TRANSPORTER >gi|7428807|pir||A69853 hexuronate
           transporter homolog yjmG - Bacillus subtilis
           >gi|2612908|gb|AAC46332.1| (AF015825) hexuronate
           transporter-like protein [Bacillus subtilis]
           >gi|2633590|emb|CAB13093.1| (Z99110) similar to
           hexuronate transporter [Bacillus subtilis]
           Length = 422
           
 Score =  130 bits (323), Expect = 3e-29
 Identities = 104/397 (26%), Positives = 183/397 (45%), Gaps = 37/397 (9%)

Query: 2   EKLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAG 61
           +KL +++ + L  + NY  R A+   AP I  DL ++  ++GL+ +S  + Y++     G
Sbjct: 5   DKLPVILFLFLAGVINYLDRSALSIAAPFIQDDLTLSATQMGLIFSSFSIGYAIFNFLGG 64

Query: 62  YIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISEL 121
              D+ G K  L ++++ +SL S  + L   +  L+ +R L+G   G   A    +++  
Sbjct: 65  VASDRYGAKLTLFVAMVVWSLFSGAVALAFGFVSLLIIRILFGMGEGPLSATINKMVNNW 124

Query: 122 F-RERKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIK 180
           F   ++ S +G    G  +G  I+  IV  +A+  SW+ +F+++ I+  I  +L    +K
Sbjct: 125 FPPTQRASVIGVTNSGTPLGGAISGPIVGMIAVAFSWKVSFVLIMIIGLIWAVLWFKFVK 184

Query: 181 GEP---------IKVE-GVKFKIPRGVFLLSLANFLGLGAFFA-------MLTFLVSYLV 223
            +P         IK E     KIP   +L          AFFA        LT+  SYLV
Sbjct: 185 EKPQETIKEAPAIKAETSPGEKIPLTFYLKQKTVLFTAFAFFAYNYILFFFLTWFPSYLV 244

Query: 224 -SRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSP 282
             RG+ +E  S++  +  ++G +G    GF+ D++ K +       +  +  +  +  S 
Sbjct: 245 DERGLSVESMSVITVIPWILGFIGLAAGGFVSDYVYKKTARKGVLFSRKVVLVTCLFSSA 304

Query: 283 LFLIPLGLV----------------LYSVGGIMTAYTSEKASRENLGVVMGFVNMVGFFG 326
           + +   GLV                LY  G I  A   +   + N+G V GF++ +    
Sbjct: 305 VLIGFAGLVATTAGAVTLVALSVFFLYLTGAIYWAVIQDVVDQNNVGSVGGFMHFLANTA 364

Query: 327 ATIGPYIVGFLIDRLG-YSLA-LLSVPLAYLVSAVII 361
             IGP + GF++D+ G +S A LL+  LA   S  +I
Sbjct: 365 GIIGPALTGFIVDQTGTFSGAFLLAGGLAVFASLAVI 401


>pir||D71144 hypothetical protein PH0367 - Pyrococcus horikoshii
           >gi|3256758|dbj|BAA29441.1| (AP000002) 457aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 457
           
 Score =  116 bits (287), Expect = 5e-25
 Identities = 105/402 (26%), Positives = 181/402 (44%), Gaps = 54/402 (13%)

Query: 5   IILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIG 64
           I +IL+ L   F  + +  +P     IMK+ GI   ++G + +  +   +LI +  G + 
Sbjct: 21  ISIILLVLMATFLMADQNLLPPNYQQIMKEFGIGETQMGFVSSIFVATSALITIIWGMLA 80

Query: 65  DKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRE 124
           D   RKKLL I +L   +   L      YW L+T+R L G   G       +LI+++F E
Sbjct: 81  DIKQRKKLLVIGVLLGEIPCFLTAYVHSYWQLLTMRFLTGIGIGSIIPIGYSLIADMFEE 140

Query: 125 RKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKGEPI 184
            K    G+  +  A G G    +++   +T SWR  F++ ++ + I+  L  + I  EP 
Sbjct: 141 EK-RGRGYSYIETAFGFGTLFGMIIAGVIT-SWRTPFIIAAVPNFILAPLFYI-IAEEPR 197

Query: 185 KVEG---VKFKIPRGV--------------------FLLSLANFLGLGAFFAMLTFLVSY 221
           + EG   ++  I +G                      L+ L   +G   +  ++ +L+S+
Sbjct: 198 RGEGEREIRVLIEKGYEYAYKLSLEAVKKSLKTRTNILIFLQGIIGTVPWGILMYWLISF 257

Query: 222 L-VSRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIP 280
           L V+RG+  + A+ M  ++ +  +LGS+  GF+ D+           +  +  FL ++  
Sbjct: 258 LQVTRGMDKQTATFMLLIIGIASVLGSLFGGFVGDYFETRKRGGRAVITGIAIFLGMIAA 317

Query: 281 SPLFLIP----------LGLVLYSV---------GGIMTAYTSEKASRENLGVVMGFVNM 321
             L L P          LGL +YS+         G  + A  S+    E+ G V G  N+
Sbjct: 318 IGLILYPLPSKLNTIHWLGLTVYSILFIQFVSYAGPNVRAIVSQVNLPEDRGTVFGLFNI 377

Query: 322 VGFFGATIGPYIVGFLID---RLGYSLALLSVPLAYLVSAVI 360
           +   G  IGP + GFLI+   ++GY     + PLAY  + +I
Sbjct: 378 LDNVGKAIGPVLGGFLIETLVQMGY-----TKPLAYQYTLLI 414


>gb|AAG28456.1|AF195244_3 (AF195244) putative transporter [Pyrococcus furiosus]
           Length = 443
           
 Score =  111 bits (275), Expect = 1e-23
 Identities = 104/403 (25%), Positives = 185/403 (45%), Gaps = 48/403 (11%)

Query: 1   MEKLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPA 60
           + + + ++L+ L   F  + +  +P     IMK+ GI   ++GL+ +  +   +LI +  
Sbjct: 4   IRRRVSIVLLILMAAFLMADQNLLPPNYQQIMKEFGIGETQMGLVSSIFVATSALITIIW 63

Query: 61  GYIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISE 120
           G + D   RKKLL I +L   +   L    + YW L+ +R L G   G       +LI++
Sbjct: 64  GMLADIKQRKKLLVIGVLLGEIPCFLTAYVQTYWQLLAMRFLTGIGIGSIIPIGYSLIAD 123

Query: 121 LFRERKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIK 180
           +F E K    G+  +  A G G T   ++   +  SWR  F++ ++ + I+  L  + I 
Sbjct: 124 MFEEEK-RGRGYSYIETAFGFG-TLFGMIIAGMIASWRTPFIIAAVPNFILAPLFYI-IA 180

Query: 181 GEPIKVEG---VKFKIPRGV--------------------FLLSLANFLGLGAFFAMLTF 217
            EP +  G   ++  I +G                      L+ L   +G   +  +L +
Sbjct: 181 EEPKRGAGEKEIRALIEKGYEYTYRLNLEAIRKSFQTKTNILIFLQGIIGTVPWGILLYW 240

Query: 218 LVSYL-VSRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHL------GKVSVL-LAYALN 269
           LVS+L V+RG+    A+ +  ++ +  + GS++ GF+ D+       G+ ++  +A  L 
Sbjct: 241 LVSFLQVTRGMDKSTATFVLLIIGIASVFGSLLGGFVGDYFEAKRRGGRATITGIAIFLG 300

Query: 270 SLLTFLVIVIPSPLFLIP---LGLVLYSV---------GGIMTAYTSEKASRENLGVVMG 317
            L +  +I+ P P  L     +GL +YS+         G  + A  S+    E+ G V G
Sbjct: 301 MLASIGLILYPLPSKLSTVHWIGLAIYSILFIQFVSYAGPNVRAIVSQVNLPEDRGTVFG 360

Query: 318 FVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVI 360
             N++   G  IGP   GFLI+ L  S+  +  PLAY  + +I
Sbjct: 361 LFNILDNVGKAIGPLFGGFLIETL-KSMGYME-PLAYQYTLLI 401


>gb|AAD46810.1|AF157643_4 (AF157643) putative transporter protein [Mycobacterium smegmatis]
           Length = 413
           
 Score =  107 bits (265), Expect = 2e-22
 Identities = 105/412 (25%), Positives = 189/412 (45%), Gaps = 55/412 (13%)

Query: 5   IILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIG 64
           ++L+L+++    NY  R ++    P I +D  I+    GLL+++    Y+ +Q+PAG++ 
Sbjct: 4   LLLLLVTV----NYVDRGSLSVALPAIKEDFHISAEVTGLLLSAFFWAYAAMQIPAGWLI 59

Query: 65  DKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELF-- 122
           D+ G +KL+T +  G+  ++AL  +  +   +   R L G        PA   ++ +F  
Sbjct: 60  DRFGPRKLITAACTGWGTATALSGMAPNIGTMAVARGLIG-VTEAPIMPAGGKLNAVFLT 118

Query: 123 RERKGSALGFFMVGPAIGSGITPL-IVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKG 181
            + +G        G  +GS +  +     +  T SWR+AF++   ++ ++GI    AI+ 
Sbjct: 119 EKERGRGATILDAGAPLGSAVGGIAFAALIGATGSWRWAFIIAGAVTVLLGIWAWRAIRD 178

Query: 182 EP---IKVE-------------------------GVKFKIPRGVFLLSLANFLGL-GAFF 212
            P    KV+                         G+ + +    F    A +LG  G F+
Sbjct: 179 TPEEHPKVDEAEREYLVSAHREESARHQSTGERAGLVYYMKYRSFWAMCAGWLGFNGVFY 238

Query: 213 AMLTFLVSYLVSRGVGMEKASLMFSMLSLV--GILGSIIAGFLYDHLGKVSVLLAYALNS 270
            +LT+   +L S   G E  ++ +S  ++   G +G II G L D L +        + S
Sbjct: 239 GLLTWGPLFL-SESKGFELEAIGWSTFAIFGSGFVGEIIGGQLADRLKEKGYGTNRVMRS 297

Query: 271 LLTFL----------VIVIPSPL-FLIPLGLVLYSVG--GIMTAYTSEKASRENLGVVMG 317
           LL F           V+++PSPL  ++ L  VL+ +   G+  +  S    RE+ GV+ G
Sbjct: 298 LLGFAGMCVVAGLVGVVLMPSPLAAVLLLSTVLFFLRWVGLFWSVPSILGGREDAGVLGG 357

Query: 318 FVNMVGFFGATIGPYIVGFLIDRLG-YSLALL-SVPLAYLVSAVIIGLDLRK 367
            +N+ G     + P  VGF++   G Y+ ALL  V    +++A ++ LD  K
Sbjct: 358 AMNLAGNISGFVTPMAVGFIVGATGAYTWALLYFVGAGVIMTAAVLILDYSK 409


>gb|AAK41360.1| Transport membrane protein (permease) [Sulfolobus solfataricus]
           Length = 378
           
 Score =  106 bits (261), Expect = 6e-22
 Identities = 85/352 (24%), Positives = 159/352 (45%), Gaps = 19/352 (5%)

Query: 6   ILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGD 65
           ++ L +  +  +Y  R+    +AP+    L     E  ++     L Y L+Q+P+G + D
Sbjct: 6   VIFLSASSFFLSYFSRVTWSIVAPL--STLKTTTTEDSIIFALFFLGYILVQIPSGMLAD 63

Query: 66  KIGRKKLLTISILGYS----LSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISEL 121
           +I    LL +S+LG +    +SS   ++  +Y        L GF AG  Y     L+S  
Sbjct: 64  RISANHLLFLSLLGVAITSFISSTFPLIMLEY----VASFLMGFSAGWIYPITVKLLSAS 119

Query: 122 FRERK-GSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIK 180
           F  R    A+  + +   +    + +I+  +ALT  W ++F  ++ +S I+GIL ++ + 
Sbjct: 120 FDSRDLPIAMSIYSISWPLSIVASGVIIPFLALTFGWEFSFYFITALSIILGILALLYLP 179

Query: 181 GEPIKVEGVKFK---IPRGVFLLSLANFLGLGAFFAMLTFLVSYLVSRGVGMEKASLMFS 237
              +    +KFK     +    +S+  FL    ++ ++ +L  YL+S       A +++S
Sbjct: 180 SLKLSKSIIKFKDVVKDKNSIYISVGGFLFYLTYWILVLYLYKYLLSVVGNEYTAGIIYS 239

Query: 238 MLSLVGILGSIIAGFLYDHLGK----VSVLLAYALNSLL-TFLVIVIPSPLFLIPLGLVL 292
             +L GI  +I+AG++   LG     +S +  Y+ + LL +F   VI   +  + LG   
Sbjct: 240 FTALTGIFSTILAGYIIKSLGVKRTFLSFITLYSFSLLLFSFSKNVIVIGIDALALGFFR 299

Query: 293 YSVGGIMTAYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYS 344
           + +    +   +    +E  G V G  N    F   +G  I   LI+   Y+
Sbjct: 300 FVITPTSSTAVAVIGGKERSGSVTGLANFFWQFSGIVGSIIAPLLINLFTYT 351


>emb|CAC12461.1| (AL445067) transport membrane protein (permease) related protein
           [Thermoplasma acidophilum]
           Length = 382
           
 Score =  104 bits (257), Expect = 2e-21
 Identities = 78/351 (22%), Positives = 168/351 (47%), Gaps = 14/351 (3%)

Query: 1   MEKLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPA 60
           M KL  L + S  +  +Y  R++   L+  +        A+ G       + Y ++Q+P+
Sbjct: 1   MAKLYPLFVGSASFFLSYYVRLSWTILS--VYMPFKPTVAQEGFAFAIFFVGYVIVQIPS 58

Query: 61  GYIGDKIGRKKLLTISILGYSLSSALIVLTRDY-WDLVTVRALYGFFAGLYYAPATALIS 119
           G+I D+     ++++S++G ++S+ +  L+ D  W+ V+   + G  AG  Y  +  +++
Sbjct: 59  GFISDRYSGGIVISLSLIGLAVSAIMSALSPDIEWEYVS-SLIMGLTAGWVYPASINVMN 117

Query: 120 ELFRERKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGIL---LM 176
             +RE +   +G++ +   +   ++  ++  +AL + W++ +   +I S ++ I+   L 
Sbjct: 118 HYYRENRSVYIGYYSIAWPLAIVLSGFMLPYLALKIGWQWGYYSSAIASIVIAIMAFSLK 177

Query: 177 VAIKGEPIKVEGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYLVSRGVGMEKASLMF 236
               G  I    +K    R V LLS   FL   +++++  +   Y VS G+    +  +F
Sbjct: 178 TEHSGYSIDPSLIK---NRDVLLLSFGGFLFFISYWSLTLYAYKYFVSIGISPVISGFVF 234

Query: 237 SMLSLVGILGSIIAGFLYDHLG-KVSVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSV 295
           S +++ G+  + ++G++   +G K +V+++     ++      I + + LI + LV+   
Sbjct: 235 SSMAITGLFSTSLSGYIISRIGTKNAVVISLVAYGIIILAFSFIRNAVLLIVISLVMGFF 294

Query: 296 GGIMT---AYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGY 343
             I+T   +  S +  RE  G V G  NM       +GP +   LI  +G+
Sbjct: 295 RFIITPGNSGLSIEIGRERAGSVSGIANMFWQSSGIVGPIVSSALILDVGF 345


>pir||A83133 probable MFS transporter PA4096 [imported] - Pseudomonas aeruginosa
           (strain PAO1) >gi|9950297|gb|AAG07483.1|AE004826_1
           (AE004826) probable MFS transporter [Pseudomonas
           aeruginosa]
           Length = 419
           
 Score =  104 bits (257), Expect = 2e-21
 Identities = 99/392 (25%), Positives = 191/392 (48%), Gaps = 32/392 (8%)

Query: 5   IILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIG 64
           ++L ++ L + F +  R+A+  L P + ++L ++N+ +G+L + L L +++     G   
Sbjct: 13  VLLCVLFLTFGFVFFDRLALSFLFPFMEQELQLSNSHLGMLSSVLALAWAVSGALVGAWS 72

Query: 65  DKIG-RKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFR 123
           D+ G RK LL ++++ +SL SAL  L   +  L+  R + G   G     + +L+ E   
Sbjct: 73  DRRGQRKPLLIVAVILFSLCSALSGLVGGFLSLLLFRGIMGLAEGPILPLSQSLMVEASS 132

Query: 124 -ERKGSALGFFMVGPA--IGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIK 180
             R+G  +G      A  +G+ I P ++V +A  L WR+AF+V  +   ++  L+   ++
Sbjct: 133 PHRRGLNMGLLQGSAAGLLGAVIGPPLLVALAEALGWRHAFIVSLLPGLLIAWLIWRHVR 192

Query: 181 GEPIKVE----------GVKFKI--PRGVFLLSLANFLGLGAFFAMLTFLVSYLV-SRGV 227
            +P + +          G +  +   R + L +L + + +  F  +++F  ++LV +RG 
Sbjct: 193 PDPPRAQRPAPRAEEAKGKRLALLKSRNILLCTLISCVFVTWFIVLISFTPTFLVNARGF 252

Query: 228 GMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIV-IPSPLFLI 286
                  + S L +  ++       + D +G+   L+A++L +    L ++  P+   L 
Sbjct: 253 SPATMGRLMSCLGVAWVVWGFAVPAISDRIGRRPTLVAFSLLAACCPLALLYAPNATSLG 312

Query: 287 PLGLVLYSVGGIMTAY----TSEKASR----ENLGVVMGFVNMVGFFGATIGPYIVGFLI 338
            L L+ Y+  G  T +     +E  SR      LG++MG   +VG F   + P + GF  
Sbjct: 313 LLLLLTYTGLGCFTLFMATIPAETVSRGVIATALGLIMGLGELVGGF---LAPTVAGFAA 369

Query: 339 DRLGYSLAL-LSVPLAYLVSAVIIGLDLRKTS 369
           DR G S+ + +S   A L  A  + L LR+T+
Sbjct: 370 DRFGLSIVMWMSCGGALL--AAFLSLFLRETA 399


>gb|AAG20513.1| (AE005123) D-lactate dehydrogenase; Dld [Halobacterium sp. NRC-1]
           Length = 353
           
 Score =  104 bits (257), Expect = 2e-21
 Identities = 95/347 (27%), Positives = 160/347 (45%), Gaps = 24/347 (6%)

Query: 34  DLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSLSSALIVLTRDY 93
           D+ I N + G   T+L   Y+L+Q P+G + D + RK LL   +   S    ++   R Y
Sbjct: 8   DIHITNTKAGFAFTTLWGLYALLQYPSGRLSDALSRKTLLVTGLGMASGGFVVLATARSY 67

Query: 94  WDLVTVRALYGFFAGLYYAPATALISELFRERKGSALGFFMVGPAIGSGITPLIVVPVAL 153
             L+   A+ G  AGLY   A AL+++L+  ++G A G       +G G++   +  VAL
Sbjct: 68  AALLVGAAIVGTGAGLYPTAARALVADLYSTKQGRAFGLHTASGDLG-GMSAAGIAAVAL 126

Query: 154 TL-SWRYAFLVLSIMSSIVGILLMV------AIKGEPIKVEGVKFKIPRGVFLLSLANFL 206
            L SWRYAF+ +  +++ V I L V        +   + V     ++  G     +    
Sbjct: 127 ALLSWRYAFVPIVCLTAAVAIALHVWSRESYVFERRSLAVRDTAARLLSGTQFRWILVAY 186

Query: 207 GLGAFF--AMLTFLVSYLVSRGVGMEKA----SLMFSMLSLVGILGSIIAGFLYDHLGKV 260
            L AF   A+  FL ++      G E A    ++ F  L  VG +    AG L D + + 
Sbjct: 187 TLYAFTWQAIAAFLPTFFTD---GKEFAPVVGTVAFGALFAVGAIAKPTAGTLSDTISRR 243

Query: 261 SVLL-AYALNSLLTFLVIVIPSPLFLIPLGLVLYSVG-----GIMTAYTSEKASRENLGV 314
           ++ + A  L +     V+V+PSP+  +   +V+++ G      +M +Y  +    E+ G 
Sbjct: 244 ALAVGALVLGAAALSAVVVVPSPVAAVG-AVVVFAAGLLAFPPVMQSYLMDAFPPESAGG 302

Query: 315 VMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVII 361
            +G +  V      +GP  VG +     Y +A   +  A +V+AVII
Sbjct: 303 DLGAMRTVYIGLGALGPTYVGAVSTAANYEIAFWGLVGALIVAAVII 349


>pir||T44249 transport protein homolog [imported] - Arthrobacter sp.  (strain
           TE1826) >gi|3116222|dbj|BAA25927.1| (AB007122)
           transporter [Arthrobacter sp.]
           Length = 405
           
 Score =  104 bits (256), Expect = 2e-21
 Identities = 86/364 (23%), Positives = 166/364 (44%), Gaps = 17/364 (4%)

Query: 21  RMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGY 80
           RMA   L P + + L ++  ++G+L TS  + Y  + + AG +  K G KKL+ +  L  
Sbjct: 26  RMAYGILMPFMKESLSLSYQQMGMLGTSTAIGYLSLVLFAGILAAKWGSKKLVVLGNLLV 85

Query: 81  SLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRERKGSALGFFMVGPAIG 140
           +     +   + ++  +    L G  A   Y P   ++   F  R+G  +GF + G  +G
Sbjct: 86  AFGLLYLSWAQSFFACLAGMILLGIGAAFTYTPVVNIVVGWFPNRRGMMIGFVISGLGLG 145

Query: 141 SGITPLIVVPVALTLS---WRYAFLVLSIMSSIVGILLMVAIKGEP---IKVEGVKFKIP 194
           S I   ++       S   WRY +LV SI++ I  ++    ++  P    K         
Sbjct: 146 SLIASALIPFFTAWYSDNGWRYLWLVFSIIAFISAVVSYFILRDPPEVSRKTAAKSHSFL 205

Query: 195 RGVFL----LSLANFLGLGAFFAML--TFLVSYLVSRGVGMEKASLMFSMLSLVGILGSI 248
           R V+L    + +A   GL  F  ++  +FL S+++  G+    A  + S+ S++ I    
Sbjct: 206 RDVYLNHKVILVAVIYGLIGFAYLIPQSFLFSFILDTGINSYSAGQLMSLGSIMSIFSGP 265

Query: 249 IAGFLYDHLG-KVSVLLAYALNSLLTFLVIVIPSPLFLIPL----GLVLYSVGGIMTAYT 303
           + G + D +G K+S+L+   L ++   + I  P+ L  +      G+ +  +  ++ A +
Sbjct: 266 LWGAVSDKIGRKMSLLVTLLLGAVSVIIPIGFPTYLGFVICQFLWGINVVGMLSLIQALS 325

Query: 304 SEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVIIGL 363
           +E+  +    V +G+  +    G   GP + G++ID  G    +L +    L+ A ++ L
Sbjct: 326 TEQVHQSYAPVALGYTTVYFAVGQLAGPGLGGWMIDHFGGIPPVLFLCSGLLILAFLLSL 385

Query: 364 DLRK 367
            + K
Sbjct: 386 QVNK 389


>gi|11498512 conserved hypothetical protein [Archaeoglobus fulgidus]
           >gi|7483062|pir||C69363 conserved hypothetical protein
           AF0907 - Archaeoglobus fulgidus
           >gi|2649701|gb|AAB90333.1| (AE001041) conserved
           hypothetical protein [Archaeoglobus fulgidus]
           Length = 419
           
 Score =  101 bits (250), Expect = 1e-20
 Identities = 92/382 (24%), Positives = 162/382 (42%), Gaps = 34/382 (8%)

Query: 14  WIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLL 73
           + F Y HR +   LA  +M++  +    +G+L ++   PY L+Q+P GY+ D  G +   
Sbjct: 31  YFFVYFHRTSSAILATTLMEEFAVTALAVGVLSSAYFYPYGLMQIPVGYLSDTKGPRLTT 90

Query: 74  TISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRERKGSAL-GF 132
           T+  L   + + L  ++ ++   V  R L G      Y P   L+S  FR  + + L G 
Sbjct: 91  TVFTLLAFVGTVLFAVSPNFEVAVLGRFLIGIGVSGVYIPTIKLLSRWFRVDEFATLTGV 150

Query: 133 FMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKGEPIKV-----E 187
                 +G+ ++   +  +     WR  FL +  ++ ++ +   + ++  P  V     E
Sbjct: 151 LFAVGNMGALVSAYPLATMVSLFGWRVTFLFIGAITFVLALSCWIFVRDSPGGVLEKSRE 210

Query: 188 GVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSY---------LVSRGVGMEKASLMFSM 238
           G +F     V +L+   +L   + F     ++ Y         +   G+  E+A  +  M
Sbjct: 211 GGRFATNFRVVVLNPVVWLIATSAFLRYGIVMGYQGLWGGPYLMDVYGMQREEAGGVLMM 270

Query: 239 LSLVGILGSIIAGFLYD--------HLGKVSVLLAYALNSLLTFLVIVIPSPLFLIPLGL 290
           + L  ILG+ I GFL D         L    +   + +  L+ F   +    L+ I   +
Sbjct: 271 VGLGTILGAPIIGFLSDKVFRTRKWFLVAAGIGFTFTMAPLVFFTASLTVFQLYAISFLI 330

Query: 291 VLYSVGG-IMTAYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLG------- 342
            L+S  G +  A   E    E  G+    VN+  FFG  +    +G+L+D +G       
Sbjct: 331 GLFSAAGPVAYALIKESYPLEVTGLATSIVNVFPFFGGALFQVFMGYLMDTVGMVDGSYP 390

Query: 343 ---YSLALLSVPLAYLVSAVII 361
              YSLA      A +VSAV+I
Sbjct: 391 PEAYSLAFSFCLAASVVSAVLI 412


>pir||D71112 hypothetical protein PH0667 - Pyrococcus horikoshii
           >gi|3257075|dbj|BAA29758.1| (AP000003) 413aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 413
           
 Score = 98.7 bits (242), Expect = 1e-19
 Identities = 104/387 (26%), Positives = 169/387 (42%), Gaps = 41/387 (10%)

Query: 7   LILISLGWIF-NYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGD 65
           +   ++G  F N +  +  P L  + MK +G     +GLL     L  ++ Q P GY+ D
Sbjct: 31  ITFFAIGMFFANLAWGIGYPYLT-VYMKIIGGTMFLVGLLSVIYNLTSAIFQYPFGYLSD 89

Query: 66  KIGRKK-LLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPA-TALISELFR 123
           KIG++K  + + +L    +  L++       L+++R   G   G  +APA +ALISEL  
Sbjct: 90  KIGKRKPFIILGVLFSGTTYVLVIFISTPILLLSLRGTQGAL-GASFAPAHSALISEL-S 147

Query: 124 ERKGSALGFFM----VGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAI 179
            R GS  GFF     +G  +G+ +   IV  V +    + AFL  SI+S +V IL +  +
Sbjct: 148 TRVGSMFGFFNFVENMGFMVGNFLGGYIVKKVGI----KSAFLATSIVS-LVSILFLTQV 202

Query: 180 KGEPIKVEGV-------------KFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYLVSRG 226
           K    K + +             K ++    F + +   LG      +L  + S  V   
Sbjct: 203 KERERKKKNIGSFLPIREGRESEKVEMKSSAFKMLMKGELGAFYLSVLLAMIASGEVYAT 262

Query: 227 V--------GMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIV 278
           V        G E    +  + SL   LGS++ G L D  G+        L  +LTF+   
Sbjct: 263 VPVYFQEKFGEEFVGFLLGIDSLAAALGSLLIGRLIDKYGEKVFYKLAILGYILTFIGYA 322

Query: 279 IPSPLFLIPLGLVLYSVGGIM-----TAYTSEKASRENLGVVMGFVNMVGFFGATIGPYI 333
             + + ++ L  +L  V   M     + Y + +      G  MG +N +   G  IGP I
Sbjct: 323 WATTIIIMALVSLLSGVKWAMITSSASTYVARRVPHRERGQGMGLLNTMMTLGWVIGPLI 382

Query: 334 VGFLIDRLGYSLALLSVPLAYLVSAVI 360
            G + D  G+S+ L S  L  +VS ++
Sbjct: 383 GGLIADNFGFSVMLYSTTLPLIVSFLL 409


>sp|P31457|DGOT_ECOLI D-GALACTONATE TRANSPORTER
           Length = 430
           
 Score = 95.2 bits (233), Expect = 1e-18
 Identities = 83/404 (20%), Positives = 171/404 (41%), Gaps = 47/404 (11%)

Query: 3   KLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGY 62
           + + L++I +  +  Y  R  +   +  I ++ GI  AE+G + ++    Y+L Q+P G+
Sbjct: 14  RYLTLVMIFITVVICYVDRANLAVASAHIQEEFGITKAEMGYVFSAFAWLYTLCQIPGGW 73

Query: 63  IGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELF 122
             D++G +    I+I G+S+++           L+ +RA+ G F    +     +++  F
Sbjct: 74  FLDRVGSRVTYFIAIFGWSVATLFQGFATGLMSLIGLRAITGIFEAPAFPTNNRMVTSWF 133

Query: 123 RE-RKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLV---LSIMSSIVGILLM-- 176
            E  + SA+GF+  G  +G      +++ +   LSW + F+V   + I+ S++   +   
Sbjct: 134 PEHERASAVGFYTSGQFVGLAFLTPLLIWIQEMLSWHWVFIVTGGIGIIWSLIWFKVYQP 193

Query: 177 -------------------------VAIKGE---PIKVEGVKFKIPRGVFLLSLANFLGL 208
                                      +K E   P+  +  K    R +  + L  F   
Sbjct: 194 PRLTKGISKAELDYIRDGGGLVDGDAPVKKEARQPLTAKDWKLVFHRKLIGVYLGQFAVA 253

Query: 209 GAFFAMLTFLVSYLV-SRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYA 267
              +  LT+  +YL   +G+   KA  M ++  L   +G +++G++ D L +    L +A
Sbjct: 254 STLWFFLTWFPNYLTQEKGITALKAGFMTTVPFLAAFVGVLLSGWVADLLVRKGFSLGFA 313

Query: 268 LNSLLTFLVIV---------IPSPLFLIPLGLVLYSVGG---IMTAYTSEKASRENLGVV 315
             + +   +++            P+ ++ L  + +   G   I  +  S  A    +G+ 
Sbjct: 314 RKTPIICGLLISTCIMGANYTNDPMMIMCLMALAFFGNGFASITWSLVSSLAPMRLIGLT 373

Query: 316 MGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAV 359
            G  N  G  G    P +VG+L    G++ AL+ +    L+ A+
Sbjct: 374 GGVFNFAGGLGGITVPLVVGYLAQGYGFAPALVYISAVALIGAL 417


>pir||D65171 hypothetical 48.8 kD protein in ibpA-gyrB intergenic region -
           Escherichia coli >gi|290540|gb|AAA62043.1| (L10328) f445
           [Escherichia coli] >gi|1790126|gb|AAC76714.1| (AE000446)
           D-galactonate transport [Escherichia coli K12]
           Length = 445
           
 Score = 95.2 bits (233), Expect = 1e-18
 Identities = 83/404 (20%), Positives = 171/404 (41%), Gaps = 47/404 (11%)

Query: 3   KLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGY 62
           + + L++I +  +  Y  R  +   +  I ++ GI  AE+G + ++    Y+L Q+P G+
Sbjct: 29  RYLTLVMIFITVVICYVDRANLAVASAHIQEEFGITKAEMGYVFSAFAWLYTLCQIPGGW 88

Query: 63  IGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELF 122
             D++G +    I+I G+S+++           L+ +RA+ G F    +     +++  F
Sbjct: 89  FLDRVGSRVTYFIAIFGWSVATLFQGFATGLMSLIGLRAITGIFEAPAFPTNNRMVTSWF 148

Query: 123 RE-RKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLV---LSIMSSIVGILLM-- 176
            E  + SA+GF+  G  +G      +++ +   LSW + F+V   + I+ S++   +   
Sbjct: 149 PEHERASAVGFYTSGQFVGLAFLTPLLIWIQEMLSWHWVFIVTGGIGIIWSLIWFKVYQP 208

Query: 177 -------------------------VAIKGE---PIKVEGVKFKIPRGVFLLSLANFLGL 208
                                      +K E   P+  +  K    R +  + L  F   
Sbjct: 209 PRLTKGISKAELDYIRDGGGLVDGDAPVKKEARQPLTAKDWKLVFHRKLIGVYLGQFAVA 268

Query: 209 GAFFAMLTFLVSYLV-SRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYA 267
              +  LT+  +YL   +G+   KA  M ++  L   +G +++G++ D L +    L +A
Sbjct: 269 STLWFFLTWFPNYLTQEKGITALKAGFMTTVPFLAAFVGVLLSGWVADLLVRKGFSLGFA 328

Query: 268 LNSLLTFLVIV---------IPSPLFLIPLGLVLYSVGG---IMTAYTSEKASRENLGVV 315
             + +   +++            P+ ++ L  + +   G   I  +  S  A    +G+ 
Sbjct: 329 RKTPIICGLLISTCIMGANYTNDPMMIMCLMALAFFGNGFASITWSLVSSLAPMRLIGLT 388

Query: 316 MGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAV 359
            G  N  G  G    P +VG+L    G++ AL+ +    L+ A+
Sbjct: 389 GGVFNFAGGLGGITVPLVVGYLAQGYGFAPALVYISAVALIGAL 432


>gb|AAD10060.1| (AF113952) multidrug-efflux transporter [Campylobacter jejuni]
           Length = 431
           
 Score = 94.8 bits (232), Expect = 1e-18
 Identities = 92/355 (25%), Positives = 166/355 (45%), Gaps = 29/355 (8%)

Query: 22  MAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYS 81
           + +P L+   +K  G N   +GLL+    L   ++Q+P G + DKIGRKK + I ++ + 
Sbjct: 21  IVLPVLSLYALKLEGANEFLVGLLVGVYALTQMILQMPFGILSDKIGRKKTMLIGLIIFI 80

Query: 82  LSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISE-LFRERKGSALGFFMVGPAIG 140
           + S +     + + ++  R L G  AG   A ATA+IS+ +  E +G A+   ++G  IG
Sbjct: 81  IGSLICSFAENIYTMLLGRMLQG--AGAIGAVATAMISDFITEENRGKAMA--VMGSFIG 136

Query: 141 SGITPLIVVPVALTLSWRYAFLV-LSIMSSIVGILLMVAIKGEPIKVEGVKFKIP----- 194
                 +V+   ++  W  + L  LS   S++ I+L+  +  +  K+     K P     
Sbjct: 137 LSFAASMVISPLMSAKWGLSSLFDLSAALSLLCIILLYTVVPKENKITHENEKTPFFHLI 196

Query: 195 --RGVFLLSLANF----LGLGAFFAMLTFLVSYLVSRGVGMEKASLMFSMLSLVGILGSI 248
             + + L++L NF    L   AF ++   LV +L   G   +K  +++S   + G +   
Sbjct: 197 KQKNLALMNLTNFMQKMLMSIAFLSIPIILVKHL---GFASDKLWIVYSASMVAGFIAMG 253

Query: 249 IAGFLYDHLGKV-SVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSVG-----GIMTAY 302
            AG L +  G    +LL   +  +L++L     + +    + +V++ +G      IM + 
Sbjct: 254 FAGSLGEKRGLAKQILLLGIVFFILSYLFFAFSNSIDFFIIAVVIFFIGFNLHEPIMQSC 313

Query: 303 TSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFL--IDRLGYSLALLSVPLAYL 355
            S+       G  +G  N  G+ G+ IG  I G    +D L   LA++ V LA +
Sbjct: 314 ASKFCKVHEKGAALGLFNAFGYGGSFIGGIIGGIFLHLDTLNL-LAIILVILALI 367


>pir||D81282 probable efflux protein Cj1375 [imported] - Campylobacter jejuni
           (strain NCTC 11168) >gi|6968809|emb|CAB73802.1|
           (AL139078) putative efflux protein [Campylobacter
           jejuni]
           Length = 431
           
 Score = 94.8 bits (232), Expect = 1e-18
 Identities = 92/355 (25%), Positives = 166/355 (45%), Gaps = 29/355 (8%)

Query: 22  MAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYS 81
           + +P L+   +K  G N   +GLL+    L   ++Q+P G + DKIGRKK + I ++ + 
Sbjct: 21  IVLPVLSLYALKLEGANEFLVGLLVGVYALTQMILQMPFGILSDKIGRKKTMLIGLIIFI 80

Query: 82  LSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISE-LFRERKGSALGFFMVGPAIG 140
           + S +     + + ++  R L G  AG   A ATA+IS+ +  E +G A+   ++G  IG
Sbjct: 81  IGSLICSFAENIYTMLLGRMLQG--AGAIGAVATAMISDFITEENRGKAMA--VMGSFIG 136

Query: 141 SGITPLIVVPVALTLSWRYAFLV-LSIMSSIVGILLMVAIKGEPIKVEGVKFKIP----- 194
                 +V+   ++  W  + L  LS   S++ I+L+  +  +  K+     K P     
Sbjct: 137 LSFAASMVISPLMSAKWGLSSLFDLSAALSLLCIILLYTVVPKENKITHENEKTPFFHLI 196

Query: 195 --RGVFLLSLANF----LGLGAFFAMLTFLVSYLVSRGVGMEKASLMFSMLSLVGILGSI 248
             + + L++L NF    L   AF ++   LV +L   G   +K  +++S   + G +   
Sbjct: 197 KQKNLALMNLTNFMQKMLMSIAFLSIPIILVKHL---GFASDKLWIVYSASMVAGFIAMG 253

Query: 249 IAGFLYDHLGKV-SVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSVG-----GIMTAY 302
            AG L +  G    +LL   +  +L++L     + +    + +V++ +G      IM + 
Sbjct: 254 FAGSLGEKKGLAKQILLLGIVFFILSYLFFAFSNSIDFFIIAVVIFFIGFNLHEPIMQSC 313

Query: 303 TSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFL--IDRLGYSLALLSVPLAYL 355
            S+       G  +G  N  G+ G+ IG  I G    +D L   LA++ V LA +
Sbjct: 314 ASKFCKVHEKGAALGLFNAFGYGGSFIGGIIGGIFLHLDTLNL-LAIILVILALI 367


>pir||E75048 multidrug resistance protein PAB0913 - Pyrococcus abyssi  (strain
           Orsay) >gi|5458795|emb|CAB50282.1| (AJ248287) multidrug
           resistance protein [Pyrococcus abyssi]
           Length = 410
           
 Score = 94.4 bits (231), Expect = 2e-18
 Identities = 99/383 (25%), Positives = 171/383 (43%), Gaps = 42/383 (10%)

Query: 7   LILISLGWIF-NYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGD 65
           +++ ++G  F +++  +  P L  + MK +G     +GLL     L  ++ Q P GY+ D
Sbjct: 28  ILMFAIGMFFADFAWGLGFPYLG-VYMKLIGGTMFLVGLLSVVYNLTSTIFQYPFGYLSD 86

Query: 66  KIGRKK-LLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPA-TALISELFR 123
           K G++K  + + IL    +  L+ L      L+ +RA  G   G   APA +ALISEL  
Sbjct: 87  KTGKRKPFIILGILASGTTYGLVALITSPILLLGLRAFQGAL-GASLAPAHSALISEL-S 144

Query: 124 ERKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIK--- 180
            R GS  GFF     +G          +  TL  +  F++ S++S ++GIL ++ IK   
Sbjct: 145 PRIGSMFGFFGFVENLGFMAGNFAGGYIVKTLGMKMMFIITSLVS-LIGILFLLKIKERG 203

Query: 181 -----------------GEPIKVEGVKFKIPR----GVFLLS-LANFLGLGAFFAMLTFL 218
                             + ++++ + FK       G+F ++ L   +  GA +A     
Sbjct: 204 RAKAGGDRLIIVKEGRESDRVELKEIAFKKLMKGRLGIFYVAVLLAMIASGAVYAT---- 259

Query: 219 VSYLVSRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIV 278
           VS       G E    +F + SL   L ++I G L D  G+        +  ++TF+   
Sbjct: 260 VSVYFEEKFGEEFVGYLFGIDSLSAALSALIIGRLIDKYGEKLFFRLSLVGYIITFMGYA 319

Query: 279 IPSPLFLIPLGLVLYSVGGIM-----TAYTSEKASRENLGVVMGFVNMVGFFGATIGPYI 333
           + + + ++ L  +L  +   M     + Y + +      G  MG +N +   G  IGP I
Sbjct: 320 LANSVIIMALISILSGLKWTMLTNSSSTYVARRVPTSERGQGMGLLNTMMTLGWVIGPLI 379

Query: 334 VGFLIDRLGYSLALLS-VPLAYL 355
            G L D  G+++ L S VP+ +L
Sbjct: 380 GGILADNFGFAVMLYSTVPILFL 402


>pir||D83160 nitrite extrusion protein 1 PA3877 [imported] - Pseudomonas
           aeruginosa (strain PAO1) >gi|2765452|emb|CAA75538.1|
           (Y15252) nitrate extrusion protein [Pseudomonas
           aeruginosa] >gi|9950057|gb|AAG07264.1|AE004805_2
           (AE004805) nitrite extrusion protein 1 [Pseudomonas
           aeruginosa]
           Length = 431
           
 Score = 90.5 bits (221), Expect = 3e-17
 Identities = 88/374 (23%), Positives = 154/374 (40%), Gaps = 39/374 (10%)

Query: 6   ILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGD 65
           +L + +L +  N++       +   I  +LG++ ++ GL++   +L  SL+++P G I D
Sbjct: 11  VLGMSTLSFAVNFAVWTMFSIIGIRIKDELGLSESQFGLMVALPILTGSLVRLPLGLITD 70

Query: 66  KIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELF-RE 124
           + G + +  I +L  ++    +     YW  + V  L+   AG  +A   A  S  F +E
Sbjct: 71  RFGGRIVFFIHMLLVAIPIYGLAFASQYWHYL-VLGLFVGLAGGSFAVGIAYTSAWFEKE 129

Query: 125 RKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKGEPI 184
           R+G+A+G F  G A G+ IT L+   + +   WR    V S+   +  +L  +    +P 
Sbjct: 130 RQGTAMGIFGAGNA-GAAITNLVAPMIVVAFGWRMVPQVYSVAMLVTAVLFWLFTWTDPA 188

Query: 185 KVEGVKFKIPR-------------GVFLLSLANFLGLGAFFAMLTFLVSYLVSR-GVGME 230
            ++G      R              V+   L  F   G F A+  +L  Y ++  G+ ++
Sbjct: 189 HLKGAAEASQRPNLAKQLAPLAELRVWRFGLYYFFVFGGFVALALWLPKYYIAEYGLDLK 248

Query: 231 KASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLI---- 286
            AS +  + +L   L   + G+  DH G  SV        L+    +  P     I    
Sbjct: 249 TASFITMLFTLPSGLIRALGGWFSDHYGARSVNWGVFWVCLVCLFFLSYPQTTMTIHGIQ 308

Query: 287 ---PLGL--------VLYSVGGIMTAYTSEKASR-------ENLGVVMGFVNMVGFFGAT 328
               LG+         L  V GI   +      R        N+G V G V ++G  G  
Sbjct: 309 GDLSLGIGLNVWLFTFLVFVVGIAQGFGKASVYRIIHDYYPSNMGTVGGMVGVIGGLGGF 368

Query: 329 IGPYIVGFLIDRLG 342
             P + G+  D +G
Sbjct: 369 CLPILFGYAADHIG 382


>pir||F83064 probable MFS transporter PA4654 [imported] - Pseudomonas aeruginosa
           (strain PAO1) >gi|9950908|gb|AAG08041.1|AE004879_7
           (AE004879) probable MFS transporter [Pseudomonas
           aeruginosa]
           Length = 457
           
 Score = 89.7 bits (219), Expect = 5e-17
 Identities = 104/419 (24%), Positives = 183/419 (42%), Gaps = 73/419 (17%)

Query: 9   LISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLM-TSLLLPYSLIQVPAGYIGDKI 67
           ++ + ++ ++  R  +  L   I +DL I++ E+ LLM  S  L Y+L  +P G + D  
Sbjct: 20  ILMVAYVLSFIDRQILNLLVGPIRRDLAISDTEMSLLMGLSFALFYTLCGIPLGRMADNR 79

Query: 68  GRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELF-RERK 126
            R+ L+   +L +S  +A   L R YW  +T R   G         A +LI++ F RER+
Sbjct: 80  SRRGLILFGVLVWSAMTAACGLARSYWQFLTFRVGVGVGEAALSPAAYSLIADSFPRERR 139

Query: 127 GSALGFFMVGPAIGSGITPL---IVVPVALTLS------------WRYAFLVLSIMSSIV 171
            +A+  + +G  +GSG+  L   +V+  A                W+  FL+L   + ++
Sbjct: 140 ATAISVYSMGIYLGSGLAFLLGGLVIKFASAQGDVHLPLFGEVRPWQLIFLILG-AAGVL 198

Query: 172 GILLMVAIKGEPIKVEGVKFKIPRGV----------------FLLSLANFLGLGAFFAML 215
             LL++AI+    +  G    +P G                 F  +  +F G G+   + 
Sbjct: 199 FCLLLLAIREPARRGVGAGVAVPLGEVGAYLRANRKTVLCHNFGFACLSFAGYGSGAWVP 258

Query: 216 TFLVSYLVSRGVGMEKASLMF-SMLSLVGILGSIIAGFLYDHLGK---------VSVLLA 265
           TF V    + G       +++ S++++ G LG +  G L D+  K         V +L A
Sbjct: 259 TFFVR---THGWDAGHVGVVYGSIVAVFGCLGIVFGGRLADYWAKRGRSDANMRVGLLAA 315

Query: 266 YA----------LNSLLTFLVIVIPSPLFL-IPLGLVLYSVGGIMTAYTSEKASRENLGV 314
           +A          L++      ++ P+  FL +P G+   ++  IM      +AS   L V
Sbjct: 316 WAVIPFTLVYPLLDNANWAAALMAPTVFFLSMPFGVAPAAIQEIMPNSMRGQASAIYLFV 375

Query: 315 VMGFVNMVGFFGATIGPYIVGFLID-------RLGYSLALLSVPLAYLVSAVIIGLDLR 366
           V         FG  +GP  V  + D        L YSL L+++  A L + V++G+ L+
Sbjct: 376 VT-------LFGLGVGPTAVALVTDFVFADDMALRYSLLLVTL-AAVLGAVVLLGIGLK 426


>pir||S74046 probable sugar transport protein c0110 - Sulfolobus solfataricus
           >gi|1707740|emb|CAA69460.1| (Y08256) sugar transporter
           [Sulfolobus solfataricus]
           Length = 423
           
 Score = 89.7 bits (219), Expect = 5e-17
 Identities = 93/401 (23%), Positives = 178/401 (44%), Gaps = 41/401 (10%)

Query: 8   ILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKI 67
           I+ S G++ +     ++   A II+K+  +   + GLL+ + L+      +  G++ DK+
Sbjct: 17  IVTSAGFLLDGYDLNSISFAATIILKEFSLTTVKYGLLLAASLIGMIPGSIVFGWLSDKM 76

Query: 68  GRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRERK- 126
           GR K++ + +  + +   L  +++++ +L   R L G   G  Y  ++ L+SEL   R  
Sbjct: 77  GRSKIMGLDLFFFLVFGILTAISQNFVELFISRLLLGIGIGGDYPISSTLMSELSPSRSR 136

Query: 127 ----GSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKGE 182
                 ++  + VG AI SGI  L ++P   +  WRY FL+ +++S  + +L +  I+  
Sbjct: 137 GRYLTGSVAMYWVGVAI-SGIATLFLLPTG-SYFWRYVFLIGALISVPIILLRLRLIESP 194

Query: 183 PIKVEGVKFKIP-----------RGVFLLSLANFLGLGAFFAMLTFLVSYLVSRGVGMEK 231
              V   K  I            RGV  L     L +  F   + FL   + + G+G+  
Sbjct: 195 RWLVSTGKANIKEINREIENKGVRGVVDLFKGKLLKITFFVTSVWFLFD-VAAYGIGLYY 253

Query: 232 ASLMFSM--------------LSLVGILGSIIAGFLYDHLG-KVSVLLAYALNSLLTFLV 276
            +L+                 ++   +LG IIA  L D LG +V +L+     +LL +L 
Sbjct: 254 PALLEEFAFPSKYEVVLGTLAIAAASVLGYIIAELLVDSLGRRVVLLVGLGFMTLLLYLG 313

Query: 277 IV------IPSPLFLIPLGLVLYSVGGIMTAYTSEKASRENLGVVMGFVNMVGFFGATIG 330
            +      I  P F+  + L  ++ G +   Y +E        +  GF   +   G+ +G
Sbjct: 314 GIYKFTGGILVPYFMSFVALEQWA-GAVTLFYPTELYPTPVRAIGQGFATAISRVGSVLG 372

Query: 331 PYIVGFLIDRLGYSLALLSVPLAYLVSAVIIGLDLRKTSYK 371
            +    L  ++G+  +L+      L++ +I  L  ++T+ K
Sbjct: 373 VFYFPILTKQMGFFNSLIMFGSVCLIAFIISILLSKETAKK 413


>gb|AAK42313.1| Sugar transport related protein [Sulfolobus solfataricus]
           Length = 423
           
 Score = 89.7 bits (219), Expect = 5e-17
 Identities = 93/401 (23%), Positives = 178/401 (44%), Gaps = 41/401 (10%)

Query: 8   ILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKI 67
           I+ S G++ +     ++   A II+K+  +   + GLL+ + L+      +  G++ DK+
Sbjct: 17  IVTSAGFLLDGYDLNSISFAATIILKEFSLTTVKYGLLLAASLIGMIPGSIVFGWLSDKM 76

Query: 68  GRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRERK- 126
           GR K++ + +  + +   L  +++++ +L   R L G   G  Y  ++ L+SEL   R  
Sbjct: 77  GRSKIMGLDLFFFLVFGILTAISQNFVELFISRLLLGIGIGGDYPISSTLMSELSPSRSR 136

Query: 127 ----GSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKGE 182
                 ++  + VG AI SGI  L ++P   +  WRY FL+ +++S  + +L +  I+  
Sbjct: 137 GRYLTGSVAMYWVGVAI-SGIATLFLLPTG-SYFWRYVFLIGALISVPIILLRLRLIESP 194

Query: 183 PIKVEGVKFKIP-----------RGVFLLSLANFLGLGAFFAMLTFLVSYLVSRGVGMEK 231
              V   K  I            RGV  L     L +  F   + FL   + + G+G+  
Sbjct: 195 RWLVSTGKANIKEINREIENKGVRGVVDLFKGKLLKITFFVTSVWFLFD-VAAYGIGLYY 253

Query: 232 ASLMFSM--------------LSLVGILGSIIAGFLYDHLG-KVSVLLAYALNSLLTFLV 276
            +L+                 ++   +LG IIA  L D LG +V +L+     +LL +L 
Sbjct: 254 PALLEEFAFPSKYEVVLGTLAIAAASVLGYIIAELLVDSLGRRVVLLVGLGFMTLLLYLG 313

Query: 277 IV------IPSPLFLIPLGLVLYSVGGIMTAYTSEKASRENLGVVMGFVNMVGFFGATIG 330
            +      I  P F+  + L  ++ G +   Y +E        +  GF   +   G+ +G
Sbjct: 314 GIYKFTGGILVPYFMSFVALEQWA-GAVTLFYPTELYPTPVRAIGQGFATAISRVGSVLG 372

Query: 331 PYIVGFLIDRLGYSLALLSVPLAYLVSAVIIGLDLRKTSYK 371
            +    L  ++G+  +L+      L++ +I  L  ++T+ K
Sbjct: 373 VFYFPILTKQMGFFNSLIMFGSVCLIAFIISILLSKETAKK 413


>pir||A83383 probable MFS transporter PA2114 [imported] - Pseudomonas aeruginosa
           (strain PAO1) >gi|9948128|gb|AAG05502.1|AE004638_12
           (AE004638) probable MFS transporter [Pseudomonas
           aeruginosa]
           Length = 423
           
 Score = 89.3 bits (218), Expect = 6e-17
 Identities = 91/370 (24%), Positives = 164/370 (43%), Gaps = 28/370 (7%)

Query: 29  PIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSLSSALIV 88
           P ++   GI   E G + T  LL  +     AG + D+IGR   L +++L ++  + L  
Sbjct: 51  PTLIALWGIGTGEAGFIHTMTLLASAAGGWIAGILSDRIGRVLTLQLTVLWFAFFTFLCG 110

Query: 89  LTRDYWDLVTVRALYGFFAGLYYAPATALISELFRER-KGSALGFFMVGPAIGSGITPLI 147
           L ++Y  L+  R L GF  G  +     LI E+ + R +G A+G    G AIG G+T ++
Sbjct: 111 LAQNYEQLLVARTLMGFGFGGEWTAGAVLIGEVIKARDRGKAVGLVQSGWAIGWGLTAIL 170

Query: 148 VVPVALTL----SWRYAFLVLSIMSSIVGILLMVAIKGEPI------------KVEGVKF 191
              +   L    +WR A  +L ++ ++  +++   +K   I            KV   + 
Sbjct: 171 YSLMFSLLPPEEAWR-ALFMLGLLPALFVLVVRRLVKEPEIYREARQRNQGADKVSFYEI 229

Query: 192 KIPRGVFLLSLANFL---GLGAFFAMLTFLVSYL-VSRGVGMEKASLMFSMLSLVGILGS 247
             P  + +   A+ L    LG ++A+  +L ++L   RG+ +   S   +M+ L   +G 
Sbjct: 230 FAPGMLSITLRASLLTTGALGGYYAITAWLPTFLKTERGLTVLGTSGYLAMVILGSYVGY 289

Query: 248 IIAGFLYDHLGKVSVLLAYALNS-----LLTFLVIVIPSPLFL-IPLGLVLYSVGGIMTA 301
           +++ FL D +G+    + +A+ S     L T L +   + L+L  PLG     +   M +
Sbjct: 290 VVSAFLTDLIGRKKNFVLFAVGSFTVVLLYTQLPVSNGAMLWLGFPLGFFASGIFSGMGS 349

Query: 302 YTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVII 361
           + +E       G   GF    G   A + P ++G L  +L   L + +         ++ 
Sbjct: 350 FLTELFPTRIRGSGQGFCYNAGRAIAALFPMLIGMLGQKLSLGLGIGAFAAVSYGVVILA 409

Query: 362 GLDLRKTSYK 371
            L L +T  K
Sbjct: 410 ALSLPETRGK 419


>pir||F71713 glycerol-3-phosphate transporter (glpT) RP054 - Rickettsia
           prowazekii >gi|3860624|emb|CAA14525.1| (AJ235270)
           GLYCEROL-3-PHOSPHATE TRANSPORTER (glpT) [Rickettsia
           prowazekii]
           Length = 429
           
 Score = 87.8 bits (214), Expect = 2e-16
 Identities = 86/410 (20%), Positives = 170/410 (40%), Gaps = 44/410 (10%)

Query: 3   KLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGY 62
           ++ IL  I +G+   Y  R       P I +  G+   +IG ++T+  + Y + +   G+
Sbjct: 23  RIRILYSIVIGYATFYFCRQNFNIATPAIREYFGVTKTQIGWILTAASIMYGVSKACNGF 82

Query: 63  IGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELF 122
           I DK+  +  + + +L   + + LI  +   W +  +     +F  + + PAT +++  F
Sbjct: 83  ISDKVNARIFMVLGLLFVGIITILIGFSDFLWLIGILWIASNWFQSMGWPPATKMLTHWF 142

Query: 123 RERK-GSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKG 181
             ++ G+          IG  +  +    +     WR AF V  +++ +  + L   ++ 
Sbjct: 143 AAKELGTKWAIGATSNQIGGALAMISCGYLIDKFDWRAAFFVPGLVACVASLFLYNRLRN 202

Query: 182 EPIK-----VEGVKFKIPRG---------------------VFLLSLAN----FLGLGAF 211
            P +     VE  K   P                       ++ + LAN     +  G  
Sbjct: 203 SPKEVGLSTVEEYKEYPPEAIGNYERLLTKQLLKMVFCNKLIWYVCLANMFVYIIRSGVI 262

Query: 212 FAMLTFLVSYLVSRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHL-----GKVSVLLAY 266
           +   TFL      R +    A L   +  ++GI G++IAG L D L     G ++ +   
Sbjct: 263 YWAPTFLKDL---RNISFVNAGLQIGLYEMIGIPGALIAGILSDKLFQGRRGPIASICMI 319

Query: 267 ALNSLLT-FLVIVIPSPLF-LIPLGLVLYSVGG---IMTAYTSEKASRENLGVVMGFVNM 321
            L  LL  F  + I S L  ++ L L+ + V G   ++    ++ ++R+ +G   G   +
Sbjct: 320 LLTLLLVLFWKVPIQSELLSILILALIGFFVAGPQLLVGIAAADFSTRQAVGTANGLSGL 379

Query: 322 VGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVIIGLDLRKTSYK 371
            G+ GA I    VG++ D  G++   +   ++ L+  V+  L    ++ K
Sbjct: 380 FGYLGAAIAGVGVGWISDNYGWNGVFIFFSISALLGGVLFALTWNHSAEK 429


>pir||T46710 multidrug resistance transporter [imported] - Listeria
           monocytogenes >gi|4914624|emb|CAB43715.1| (AJ009627)
           multidrug resistance transporter [Listeria
           monocytogenes]
           Length = 397
           
 Score = 87.4 bits (213), Expect = 2e-16
 Identities = 83/363 (22%), Positives = 153/363 (41%), Gaps = 20/363 (5%)

Query: 24  VPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSLS 83
           V  L P I + +G +++++ +L T+ +   +++ +P G +  K+G KKL+ I +   ++ 
Sbjct: 28  VDPLLPSIAESIGASHSQVEMLFTAYIFTMAIMMIPIGIVAGKMGDKKLIVIGLFIVTIF 87

Query: 84  SALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRERKGSALGFFMVGPAIGSGI 143
           + L  L+     L   RA +GF   ++ A A  ++  L  E  G A+G +     +G   
Sbjct: 88  ALLCGLSDTIGALSIFRAGWGFGNSMFMATAMTMLIAL-SETPGHAIGIYEASMGLGMAF 146

Query: 144 TPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKGEPIKV-----EGVKFKIPRGVF 198
            PL+   +   +SWRY F   + +  I  +L++  +K EP KV     E  +  I + + 
Sbjct: 147 GPLL-GGILGNISWRYPFFATACLIFIAFLLILFKVK-EPKKVAPAPTEKNEVAIKQMLH 204

Query: 199 LLSLANFL-----GLGAFFAMLTFLVSYLVSRGVGMEKASLMFSMLSLVGILGS------ 247
           L     FL     G+  ++   T L    +  G+   +   +F    L   LGS      
Sbjct: 205 LFKYRPFLQIAFSGMFYYYCFFTILAYSPLVLGLSAIQIGFVFFAWGLCLALGSAKVSHA 264

Query: 248 IIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSVGGIMTAYTSEKA 307
           +   F    + K S+L    + +LL F+         ++  GL+L     + T    E +
Sbjct: 265 LEIRFNSKQILKGSLLACAVILALLGFIDNTAVDIGLIVISGLILGINNALFTTTVMEHS 324

Query: 308 SRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVIIGLDLRK 367
                 V  G  N V + GA   P   G L + LG  +  +   +  L    ++ + L+ 
Sbjct: 325 PYAR-SVTSGAYNFVRWLGAAFAPLCSGLLSEALGMKMPFIVASIICLAGMGLLFIKLKP 383

Query: 368 TSY 370
             +
Sbjct: 384 AHF 386


>pir||G71118 hypothetical protein PH0718 - Pyrococcus horikoshii
           >gi|3257126|dbj|BAA29809.1| (AP000003) 398aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 398
           
 Score = 87.4 bits (213), Expect = 2e-16
 Identities = 89/379 (23%), Positives = 167/379 (43%), Gaps = 27/379 (7%)

Query: 6   ILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGD 65
           + +L  + ++ + S  M  P +   +   L +     G +M  +    SL +V  GYI D
Sbjct: 17  VFLLGLVSFLNDMSSEMIAPIVPTYLTDILKMGKLASGSIMGLIESLSSLFKVIFGYISD 76

Query: 66  KIGRKKLLTISILGYSLSS---ALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELF 122
              ++K  T   LGY LS+     + LT  +WD +T+R L     G+  AP  ALI+E  
Sbjct: 77  VFRKRK--TFVALGYLLSTIAKGALALTHSWWDFLTLRILDRIGKGIRTAPRDALIAESS 134

Query: 123 RERK-GSALGFFMVGPAIGSGITPLIVVPVALTLS-------WRYAFLVLSIMSSIVGIL 174
            + K G + GF  +   +G+   PL+ V +   LS       +RY FL+ +I  +I G+L
Sbjct: 135 EKGKSGKSFGFHRMMDTLGAVTGPLVAVGLLALLSKYPKELAYRYIFLISAIPGAI-GVL 193

Query: 175 LMVAIKGEPIKVEGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYLVSR----GVGME 230
           +++ +  +   +   K K    +    L  FL + A  A+  +  ++ + +    G  + 
Sbjct: 194 IVIFLVKDRGGIVKKKIKEISSLKSPHLRAFLAVVAIAALGRYSYAFTLWKVKELGYSIF 253

Query: 231 KASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIPLGL 290
           +    +++ +++  L +   G   D +GK  ++      + L  L+      L ++ L  
Sbjct: 254 QGLEFYALFNVIYALAAYPIGSYSDKVGKKKIITTGFGIAGLASLLFAYSKSLAMLMLAF 313

Query: 291 VLYSV-----GGIMTAYTSEKASRENLGVVMGFVNMVGFFGATIGP--YIVGFLIDRLGY 343
           +LY V       I  AY ++ A     G ++G  + V  FG  + P   IVG+L      
Sbjct: 314 ILYGVYMAIEDTIPRAYMADLAKEYEKGTIIGMYHTV--FGIFVFPASIIVGYLWQTYSL 371

Query: 344 SLALLSVPLAYLVSAVIIG 362
            +  L   +   ++ +++G
Sbjct: 372 EIGFLYASVMNFIAMILMG 390


>sp|P94131|MUCK_ACICA CIS,CIS-MUCONATE TRANSPORT PROTEIN >gi|1842056|gb|AAC27117.1|
           (U87258) cis,cis-muconate transport protein MucK
           [Acinetobacter sp. ADP1]
           Length = 413
           
 Score = 86.2 bits (210), Expect = 6e-16
 Identities = 89/369 (24%), Positives = 160/369 (43%), Gaps = 32/369 (8%)

Query: 31  IMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSLSSALIVLT 90
           I  +  ++  E G+L +  L   ++  +  G+  D+ GR +++ ISIL +S+ +  + LT
Sbjct: 43  IKAEFNLSTVEAGMLGSFTLAGMAIGGIFGGWACDRFGRVRIVVISILTFSILTCGLGLT 102

Query: 91  RDYWDLVTVRALYGFFAGLYYAPATALISELFRER-KGSALGFFMVGPAIGSGITPLIVV 149
           + +     +R       G  Y     L++E    + + + LG    G  +G  +  L+  
Sbjct: 103 QSFIQFGVLRFFASLGLGSLYIACNTLMAEYVPTKYRTTVLGTLQAGWTVGYIVATLLAG 162

Query: 150 PVALTLSWRYAFLVLSIMSSIVGILLMVAI---------------KGEPIKVEGVKF--- 191
            +     WR  F V +I+  ++ +L+   +               + E +K    K    
Sbjct: 163 WLIPDHGWRVLFYV-AIIPVLMAVLMHFFVPEPAAWQQSRLAPSKQTETVKTSAFKLIFQ 221

Query: 192 -KIPRGVFLL--SLANFLGLGAFFAMLTFLVSYLVSRGVGMEKASLMFSMLSLVG--ILG 246
            K  R +F+L    A FL  G ++ +  ++ SYL S  +GM+   +   M+      ILG
Sbjct: 222 DKRNRNMFILWALTAGFLQFG-YYGVNNWMPSYLESE-LGMKFKEMTAYMVGTYTAMILG 279

Query: 247 SIIAGFLYDHLGKVSVLLAYALNSLLTF-LVIVIPSP---LFLIPLGLVLYSVG-GIMTA 301
            I+AGF+ D LG+       A+ + +   L++   SP   L+L+ +   LY +  G+   
Sbjct: 280 KILAGFMADKLGRRFTYAFGAIGTAIFLPLIVFYNSPDNILYLLVIFGFLYGIPYGVNAT 339

Query: 302 YTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVII 361
           Y +E       G  +G    VG  GA I P  +GFL       L  + +  AY +  VI 
Sbjct: 340 YMTESFPTAIRGTAIGGAYNVGRLGAAIAPATIGFLASGGSIGLGFVVMGAAYFICGVIP 399

Query: 362 GLDLRKTSY 370
            L +++  Y
Sbjct: 400 ALFIKEKQY 408


>pir||E75042 transporter (major facilitator family) related PAB0874 - Pyrococcus
           abyssi (strain Orsay) >gi|5458747|emb|CAB50234.1|
           (AJ248287) TRANSPORTER (MAJOR FACILITATOR FAMILY)
           related [Pyrococcus abyssi]
           Length = 392
           
 Score = 85.8 bits (209), Expect = 7e-16
 Identities = 92/392 (23%), Positives = 177/392 (44%), Gaps = 41/392 (10%)

Query: 6   ILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGD 65
           + +L  + ++ + S  M  P +   +   L I     G +M  +    SL +V  GYI D
Sbjct: 13  VFLLGLVSFLNDMSSEMIAPIVPSYLTDILKIGKLASGSIMGLIESLSSLFKVLFGYISD 72

Query: 66  KIGRKKLLTISILGY---SLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELF 122
           K  ++K      LGY   ++S   + +T  +WD + +R L     G+  AP  ALI+E  
Sbjct: 73  KFRKRKAFVA--LGYLISTISKGALAVTHSWWDFLILRILDRIGKGIRTAPRDALIAESS 130

Query: 123 RERK-GSALGFFMVGPAIGSGITPLIVVPVAL-------TLSWRYAFLVLSIMSSIVG-- 172
            + K G + GF  +   +G+   PL+ + +          L++RY FL+ S +  ++G  
Sbjct: 131 EKGKSGKSFGFHRMMDTLGAVAGPLVAMGLLALLANYPKELAYRYIFLI-SAVPGVIGVL 189

Query: 173 -ILLMVAIKGEPI--KVEGVK-FKIPRGVFLLSLANFLGLGAFFAMLTFL----VSYLVS 224
            +LL+V  KG  +  K++G+   K       L +     LG +    T      + Y V 
Sbjct: 190 IVLLLVKDKGSEVKKKIKGISALKSSNLRIFLVIVAIAALGRYSYAFTLWKAEELGYSVF 249

Query: 225 RGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLG-KVSVLLAYALNSLLTFLVIVIPSPL 283
           +G+G       +++ +++  L +   G+  D +G K+ + + + +  L + L+    + L
Sbjct: 250 QGLG------FYALFNVIYALSAYPIGYYSDKVGKKIIITIGFGIAGLAS-LIFAYANNL 302

Query: 284 FLIPLGLVLYSV-----GGIMTAYTSEKASRENLGVVMGFVNMVGFFGATIGP--YIVGF 336
             + L  VLY +       I  AY ++ A     G V+G  + V  FG  + P   IVG+
Sbjct: 303 PTLLLAFVLYGLYMAIEDTIPRAYMADLAKEFEKGTVIGAYHTV--FGVFVFPASIIVGY 360

Query: 337 LIDRLGYSLALLSVPLAYLVSAVIIGLDLRKT 368
           L      ++  L   +  +++ +++ L ++++
Sbjct: 361 LWQTYSLTVGFLYSAVMNVIAMIMMALLIKES 392


>pir||S56504 hypothetical 46.6K protein (leuX-fecE intergenic region) -
           Escherichia coli >gi|537120|gb|AAA97175.1| (U14003) TTG
           start codon [Escherichia coli]
           >gi|1790730|gb|AAC77235.1| (AE000498) putative transport
           protein [Escherichia coli K12]
           Length = 425
           
 Score = 85.4 bits (208), Expect = 1e-15
 Identities = 89/390 (22%), Positives = 168/390 (42%), Gaps = 41/390 (10%)

Query: 12  LGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKK 71
           LG++F+    M +  +  II  DLGI + +  L+ T   +   +     G + DK GRK 
Sbjct: 42  LGYVFDGFDFMMIFYILHIIKADLGITDIQATLIGTVAFIARPIGGGFFGAMADKYGRKP 101

Query: 72  LLTISILGYSLSSALIVLTRDYWDLVTVRALYGF-FAGLYYAPATALISELFRERKGSAL 130
           ++  +I  YS+ + L  +  + + L   R + G   +G Y   +T  +    +  +  A 
Sbjct: 102 MMMWAIFIYSVGTGLSGIATNLYMLAVCRFIVGLGMSGEYACASTYAVESWPKNLQSKAS 161

Query: 131 GFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAI-KGEPIKVEGV 189
            F + G ++G+ I   I+   A    WR +F +      ++ +LL++ I K  P   E +
Sbjct: 162 AFLVSGFSVGNIIAAQIIPQFAEVYGWRNSFFI-----GLLPVLLVLWIRKSAPESQEWI 216

Query: 190 KFKI-PRGVFL-------------LSLANFLGLGAFFAMLTFLVSYLVSRGVGMEKASLM 235
           + K   +  FL             + L  F   GA + +   L SYL   GV     S +
Sbjct: 217 EDKYKDKSTFLSVFRKPHLSISMIVFLVCFCLFGANWPINGLLPSYLADNGVNTVVISTL 276

Query: 236 FSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIP------LG 289
            ++  L  + G+I  GF+ D   K+ V  A+ +  + +F+ +    PLF I       +G
Sbjct: 277 MTIAGLGTLTGTIFFGFVGD---KIGVKKAFVVGLITSFIFL---CPLFFISVKNSSLIG 330

Query: 290 LVLY-------SVGGIMTAYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLG 342
           L L+        + G++  +  +    +  G+  G +  +G  G    P +  ++    G
Sbjct: 331 LCLFGLMFTNLGIAGLVPKFIYDYFPTKLRGLGTGLIYNLGATGGMAAPVLATYISGYYG 390

Query: 343 YSLALLSVPLAY-LVSAVIIGLDLRKTSYK 371
             ++L  V +A+  +  +++G D+    YK
Sbjct: 391 LGVSLFIVTVAFSALLILLVGFDIPGKIYK 420


>sp|P39352|YJHB_ECOLI HYPOTHETICAL METABOLITE TRANSPORT PROTEIN IN LEUX-FECE INTERGENIC
           REGION
           Length = 405
           
 Score = 85.4 bits (208), Expect = 1e-15
 Identities = 89/390 (22%), Positives = 168/390 (42%), Gaps = 41/390 (10%)

Query: 12  LGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKK 71
           LG++F+    M +  +  II  DLGI + +  L+ T   +   +     G + DK GRK 
Sbjct: 22  LGYVFDGFDFMMIFYILHIIKADLGITDIQATLIGTVAFIARPIGGGFFGAMADKYGRKP 81

Query: 72  LLTISILGYSLSSALIVLTRDYWDLVTVRALYGF-FAGLYYAPATALISELFRERKGSAL 130
           ++  +I  YS+ + L  +  + + L   R + G   +G Y   +T  +    +  +  A 
Sbjct: 82  MMMWAIFIYSVGTGLSGIATNLYMLAVCRFIVGLGMSGEYACASTYAVESWPKNLQSKAS 141

Query: 131 GFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAI-KGEPIKVEGV 189
            F + G ++G+ I   I+   A    WR +F +      ++ +LL++ I K  P   E +
Sbjct: 142 AFLVSGFSVGNIIAAQIIPQFAEVYGWRNSFFI-----GLLPVLLVLWIRKSAPESQEWI 196

Query: 190 KFKI-PRGVFL-------------LSLANFLGLGAFFAMLTFLVSYLVSRGVGMEKASLM 235
           + K   +  FL             + L  F   GA + +   L SYL   GV     S +
Sbjct: 197 EDKYKDKSTFLSVFRKPHLSISMIVFLVCFCLFGANWPINGLLPSYLADNGVNTVVISTL 256

Query: 236 FSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIP------LG 289
            ++  L  + G+I  GF+ D   K+ V  A+ +  + +F+ +    PLF I       +G
Sbjct: 257 MTIAGLGTLTGTIFFGFVGD---KIGVKKAFVVGLITSFIFL---CPLFFISVKNSSLIG 310

Query: 290 LVLY-------SVGGIMTAYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLG 342
           L L+        + G++  +  +    +  G+  G +  +G  G    P +  ++    G
Sbjct: 311 LCLFGLMFTNLGIAGLVPKFIYDYFPTKLRGLGTGLIYNLGATGGMAAPVLATYISGYYG 370

Query: 343 YSLALLSVPLAY-LVSAVIIGLDLRKTSYK 371
             ++L  V +A+  +  +++G D+    YK
Sbjct: 371 LGVSLFIVTVAFSALLILLVGFDIPGKIYK 400


>pir||D83518 cis,cis-muconate transporter MucK PA1019 [imported] - Pseudomonas
           aeruginosa (strain PAO1)
           >gi|9946930|gb|AAG04408.1|AE004534_6 (AE004534)
           cis,cis-muconate transporter MucK [Pseudomonas
           aeruginosa]
           Length = 451
           
 Score = 84.7 bits (206), Expect = 2e-15
 Identities = 92/402 (22%), Positives = 164/402 (39%), Gaps = 37/402 (9%)

Query: 4   LIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYI 63
           LI  +   LG + +    M +      +  + G++N E G L +  L   ++  +  G+ 
Sbjct: 20  LIAFVFCFLGLLADGVDLMFLAYSLNSLKAEFGLSNFEAGSLGSLTLAGMAVGGIYGGWC 79

Query: 64  GDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFR 123
            D+ GR +++T +I+ +S+ +AL+ LT++YW    +R +     G  +     L+SE   
Sbjct: 80  CDRFGRVRVVTWTIVLFSIGTALLGLTQNYWQFALIRFVASLGLGSLFVACNILMSECVG 139

Query: 124 ER-KGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKGE 182
            R + + L     G  +G  +  L+   +     WR  F   ++  ++V + L   +   
Sbjct: 140 TRYRTTILAAMQAGWTVGYLVATLLAGQIIPEFGWRTLFFT-AVAPALVCLALRPWVPES 198

Query: 183 PIKVE------------------------GVKFKIP--RGVFLL-SLANFLGLGAFFAML 215
           P  +                         G     P  RG+FLL SL +   L  ++   
Sbjct: 199 PSWLAAQAGRQRPGAAPQSHAEAGGAGPLGRMLGDPETRGMFLLWSLTSCFLLFGYYGTN 258

Query: 216 TFLVSYLVSRGVGMEKASLMFSMLSLVG--ILGSIIAGFLYDHLGKVSVLLAYALNSLLT 273
            ++ SYL S  +GM   S+   M+      ILG + AG   D  G+     A A+ S   
Sbjct: 259 NWMPSYLESE-LGMNFKSMTGYMVGTYSAMILGKVAAGVCADLFGRRLTFAAGAIGSAAF 317

Query: 274 FLVIVI---PSPL--FLIPLGLVLYSVGGIMTAYTSEKASRENLGVVMGFVNMVGFFGAT 328
             +IV    PS +   LI  G +     G++  Y +E  S    G  +G    +G  GA 
Sbjct: 318 MPLIVFYHSPSNILWILITFGFIYGVPVGVLATYMTESFSTRVRGSAVGTAYNLGRIGAA 377

Query: 329 IGPYIVGFLIDRLGYSLALLSVPLAYLVSAVIIGLDLRKTSY 370
           + P  +G L   +      L + + Y+++ +I  L +    Y
Sbjct: 378 VAPAGIGLLATHVSIGAGFLVMGITYVLTGLIPALFIADRLY 419


>gi|11497979 oxalate/formate antiporter (oxlT-2) [Archaeoglobus fulgidus]
           >gi|7448836|pir||G69295 oxalate/formate antiporter
           (oxlT-2) homolog - Archaeoglobus fulgidus
           >gi|2650264|gb|AAB90866.1| (AE001079) oxalate/formate
           antiporter (oxlT-2) [Archaeoglobus fulgidus]
           Length = 397
           
 Score = 84.7 bits (206), Expect = 2e-15
 Identities = 92/371 (24%), Positives = 155/371 (40%), Gaps = 38/371 (10%)

Query: 31  IMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTIS----ILGYSLSSAL 86
           +M   G +     L  +  LL ++L+ VPAG   D+IG +K+  +      +G+ LS  +
Sbjct: 31  LMNTFGWSKTIASLPFSIFLLIFALMMVPAGRTQDRIGPRKVAMLGGVLLGVGFLLSGLI 90

Query: 87  IVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRERKGSALGFFMVGPAIGSGITPL 146
             +   YW + +   + G   GL YA    +  + F ER G A G  +    +G G++ L
Sbjct: 91  ESIQSPYWLIFSYGVIAGAGCGLGYACPIPVARKWFPERVGLATGLVV----MGFGMSAL 146

Query: 147 IVVPVALTLSWRY----AFLVLSIMSSIVGIL----------LMVAIKGEPIKVEGVKFK 192
           I  P+   L   Y     F +L ++  IV +           L       P KVE V  K
Sbjct: 147 IFAPLERILIDTYGISTTFYILGVILLIVAVFAASLLSNPPELPAVQASNPAKVEVVTGK 206

Query: 193 IPRG---------VFLLSLANFLGLGAFFAMLTFLVSYLVSRGVGMEKASLMFSMLSLVG 243
              G          ++L L+ F    A   ++  +  Y   RG+    A+   S+LS+  
Sbjct: 207 PELGPSEMLRDYRFYVLWLSFFFMALAGLMVIGHIAPYAQERGLEPLAAAFAVSILSVAN 266

Query: 244 ILGSIIAGFLYDHLGKVSVLLAYAL---NSLLTFLVIVIPSPLFLIPLGLVLYSVG---G 297
            +G   AG L D +G+   +    L    +L+ F  + +      I   ++ ++ G    
Sbjct: 267 AVGRPGAGALSDKIGRAMTMFVLFLIQGITLIAFPHVALTLITIYICAAIIGFNYGANFS 326

Query: 298 IMTAYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLG-YSLALLSVPLAYLV 356
           +  + T +    +NLGV  G V      G  +GP + G++ D  G Y +A L   +  L+
Sbjct: 327 LFPSATGDFFGTKNLGVNYGLVFTSYGVGGLVGPIMAGYVFDVTGSYEIAFLVAGVLALI 386

Query: 357 SAVIIGLDLRK 367
           +A +  L  RK
Sbjct: 387 AAFMSFLLRRK 397


>dbj|BAB05122.1| (AP001511) multidrug resistance protein [Bacillus halodurans]
           Length = 403
           
 Score = 84.7 bits (206), Expect = 2e-15
 Identities = 98/407 (24%), Positives = 184/407 (45%), Gaps = 73/407 (17%)

Query: 2   EKLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAG 61
           + L+ ++L     +    + M +P L P I  + G++  + G L+TS  +P +L+   +G
Sbjct: 6   DTLLYVVLGMAPLLMVLGNSMFIPML-PTIQAEWGLSVVQGGWLLTSFTVPAALLIPISG 64

Query: 62  YIGDKIGRKK--LLTISILGYSL---SSALIVLTRDYWDLVTVRALYGFFAGLYYAPATA 116
            + ++ G+K+  L ++ ILG      S A+++ TR +W L+T R + G   G     +  
Sbjct: 65  ILSERYGQKRIGLASLVILGTGCVLSSIAVVIETRPFWLLLTGRIIQGLGTGGLTPISLM 124

Query: 117 LISELFR-ERKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMS--SIVGI 173
           + SELF  +++  ALGF  V   IG  I+P I+  + L  SW Y+F+VL  ++  + VG 
Sbjct: 125 VASELFSGKKRNEALGFLEVSNGIGKIISP-IIGGLILLASWYYSFVVLFALALLAFVGF 183

Query: 174 LLMVAIKGEPIK------------------VEGVKFKIPRGV-----------FLLSLAN 204
             +V    EP K                   E  K  +P  +           +L +++N
Sbjct: 184 YTLV---NEPKKHETTLSARAYTKKLSQSLQENWKMFVPIFIIGSLGMLILFGYLFAVSN 240

Query: 205 FLG------LGAFFA---MLTFLVSYLVSRGVGMEKASLMFSMLSLVGILGSIIAGFLYD 255
            +G       G   A   +L  + S+  SR +  E AS  F    +VG   +++ G ++ 
Sbjct: 241 MIGEVSPFWKGVILAVPFLLFAVASFWTSRWLTPEFAS--FQKAMMVGT--TLMTGAMF- 295

Query: 256 HLGKVSVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSVGGIMTAYTSEKASRENLGVV 315
                  L+ +  +  + F+++     LF + LG+        + A T+  +      V+
Sbjct: 296 -------LMLWQHDRTILFMLV----SLFSLGLGMFFPPASAAVAALTNNVSR----SVI 340

Query: 316 MGFVNMVGFFGATIGPYIVGFLIDR--LGYSLALLSVPLAYLVSAVI 360
           M   +M  F G  +GP I GF ++R    ++++   + L++ +  V+
Sbjct: 341 MPLYSMARFLGVAVGPVIFGFWLERNISIHTMSFFIISLSFFIMCVL 387


>sp|P27669|UHPC_SALTY REGULATORY PROTEIN UHPC >gi|421217|pir||C41853 hexose phosphate
           transport system regulatory protein uhpC - Salmonella
           typhimurium >gi|154410|gb|AAA27245.1| (M89480)
           hexosephosphate transport protein [Salmonella
           typhimurium]
           Length = 442
           
 Score = 84.3 bits (205), Expect = 2e-15
 Identities = 81/398 (20%), Positives = 170/398 (42%), Gaps = 43/398 (10%)

Query: 6   ILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGD 65
           ILI I LG+   Y  R +  + AP I+    +  ++IGLL T   + Y + +  +G + D
Sbjct: 31  ILITIWLGYALFYFTRKSFNAAAPEILASGILTRSDIGLLATLFYITYGVSKFVSGIVSD 90

Query: 66  KIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELF-RE 124
           +   +  + I ++   + + L   +   W    + AL  FF G        L++  + R 
Sbjct: 91  RSNARYFMGIGLIATGVVNILFGFSTSLWAFALLWALNAFFQGFGSPVCARLLTAWYSRT 150

Query: 125 RKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKGEPI 184
            +G     +     +G  + PL++  VAL   WR   +V  +++  VG++L   ++  P 
Sbjct: 151 ERGGWWALWNTAHNVGGALIPLVMAAVALHYGWRVGMMVAGLLAIGVGMVLCWRLRDRPQ 210

Query: 185 KV----------EGVKFKIPRGVFLLS----LANFLGLGAFFAMLT--FLVSYLV----- 223
            +          + ++    +    LS    LA ++ L  +  +L+  +++ Y+V     
Sbjct: 211 AIGLPPVGDWRHDALEVAQQQEGAGLSRKEILAKYVLLNPYIWLLSLCYVLVYVVRAAIN 270

Query: 224 ---------SRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGK-----------VSVL 263
                    + GV +  A+   SM  L G +G+++AG+  D L               +L
Sbjct: 271 DWGNLYMSETLGVDLVTANTAVSMFELGGFIGALVAGWGSDKLFNGNRGPMNLIFAAGIL 330

Query: 264 LAYALNSLLTFLVIVIPSPLFLIPLGLVLYSVGGIMTAYTSEKASRENLGVVMGFVNMVG 323
           L+     L+ F   V+ +  F    G  ++    ++    +E + +E  G   GFV +  
Sbjct: 331 LSVGSLWLMPFASYVMQAACF-FTTGFFVFGPQMLIGMAAAECSHKEAAGAATGFVGLFA 389

Query: 324 FFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVII 361
           + GA++  + +  +++   ++     + +A  +SA+++
Sbjct: 390 YLGASLSGWPLAKVLEIWHWTGFFAVIAIAAGISALLL 427


>gb|AAB48105.1| (U41818) PhlE [Pseudomonas fluorescens]
           Length = 423
           
 Score = 83.9 bits (204), Expect = 3e-15
 Identities = 99/394 (25%), Positives = 178/394 (45%), Gaps = 35/394 (8%)

Query: 3   KLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGY 62
           ++++L+ +S G +     R  +  L P+IM DL ++  ++GLL   L   +    +  G 
Sbjct: 17  RMVVLLSLSFGLVG--LDRFIIMPLFPVIMHDLALDYQDLGLLSAILAFAWGGSALFMGV 74

Query: 63  IGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELF 122
              ++G K+LL +SI   SL +    L      LV +RAL G   G  + P + ++++  
Sbjct: 75  AIRRLGTKQLLVLSITLVSLLAGASALISSLMGLVLLRALMGICEGA-FTPVSIIVTDEV 133

Query: 123 RE--RKGSALGFFM-VGPAIGSGITPLIV-VPVALTLSWRYAFLVLSIMSSIVGILLMVA 178
            +  R+G  LG    + P IG  + PL+  V   +  SWR  F ++S+   +V   L   
Sbjct: 134 SQPCRRGLNLGIQQALFPIIGLCLGPLLAGVLFEMFGSWRAVFAIISLPGLLVAWYLYRT 193

Query: 179 IKGEP-------IKVEGVKFK--IPRGVFLLSLANFLG-LGAFFAMLTFLVSYLVS-RGV 227
            +          ++  G +++  +  G   L++A  L  L   F +   L SYL     +
Sbjct: 194 YQPSQAPHPRPLVEPSGSQWRTALSSGNVRLNIALMLCILTCQFVLCALLPSYLTDVLHL 253

Query: 228 GMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVL-LAYALNSLLTFLVIV---IPSPL 283
                +++ S + L G  G ++   L D LG+  V+ + + +++LL  L+I+   +P  L
Sbjct: 254 SNFSMAMIISAIGLGGFFGQLVIPGLSDQLGRKPVVSICFLISTLLVGLLIISPPLPWLL 313

Query: 284 FL-------IPLGLVLYSVGGIMTAYTSEKASRENLGVVMGFVNMVG-FFGATIGPYIVG 335
           FL       I   L+  +VG +    TSE      L    G V   G   G  + P + G
Sbjct: 314 FLQLFFLSFINFSLICITVGPL----TSESVPPSLLATATGLVVGCGEILGGGVAPVVAG 369

Query: 336 FLIDRLGYSLALLSVPLAYLVSAVIIGLDLRKTS 369
           ++    G + A+L + LA  +   ++ L L++ S
Sbjct: 370 YIAVNWGLT-AILFLALAGSLMGGLLSLRLKEAS 402


>pir||G64494 quinolone resistance protein norA homolog - Methanococcus
           jannaschii >gi|1592184|gb|AAB99579.1| (U67596)
           multidrug-efflux transporter (bmr1) [Methanococcus
           jannaschii]
           Length = 386
           
 Score = 83.9 bits (204), Expect = 3e-15
 Identities = 89/370 (24%), Positives = 156/370 (42%), Gaps = 40/370 (10%)

Query: 1   MEKLIILILISLGWIFNYSHRMAVPSLAPIIM---KDLGINNAEIGLLMTSLLLPYSLIQ 57
           +EK + +I     WI  ++  + V  +API+    + LG  N EIGL+  S  L  ++ Q
Sbjct: 4   LEKNVFVI-----WITTFTTMLGVGFIAPIMAIYAQTLGATNLEIGLIFGSFALARTVAQ 58

Query: 58  VPAGYIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATAL 117
           +P G + D  G+K  +      Y +S+ +          + VR   G F+      A + 
Sbjct: 59  IPVGVLSDIYGKKFFIVCGTFFYGVSTLMYNFVSTVLGFLIVRIFTGIFSAFVTPVAGSY 118

Query: 118 ISELF-RERKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFL---VLSIMSSIVGI 173
           I+ +  + R G  +G F     +G GI P I   +A     +  F     L I+++I+  
Sbjct: 119 IAAIAPKTRLGEYMGIFNSAITLGFGIGPFIGGILADMYGIKMPFYFCGFLGILAAIISY 178

Query: 174 LLMVAI----KGEPIKV---------EGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVS 220
           + +  I      E I V         E +K +     F+++++N +     +A   +L  
Sbjct: 179 MKLEDIVFNKNKEKIDVKKISTLFSFEFLKNRNFSSSFIINVSNVMINAGIYA---YLAL 235

Query: 221 YLVSRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLA--------YALNSLL 272
           Y ++  + + +   M ++ +++  L     G LYD LG + +++         Y L++  
Sbjct: 236 YAINYNITISQVGFMIALTNILMALLQRSFGKLYDKLGNIMIIIGIFIISFGMYLLSTST 295

Query: 273 TFLVIVIPSPLFLIPLGLVLYSVGGIMTAYTSEKASRENLGVVMGFVNMVGFFGATIGPY 332
           TFL I+  + L +I +G  + S      A       R+  G  MG        G  IG  
Sbjct: 296 TFLTIL--ASLTIIAVGSSISSTATTSLAVKDIPTHRK--GEAMGLFTTSINIGMFIGAV 351

Query: 333 IVGFLIDRLG 342
             GFL D LG
Sbjct: 352 SFGFLADILG 361


>sp|O51798|MMLH_ALCEU PROBABLE 4-METHYLMUCONOLACTONE TRANSPORTER
           >gi|2808585|emb|CAA67957.1| (X99639) transport protein
           [Ralstonia eutropha]
           Length = 428
           
 Score = 83.9 bits (204), Expect = 3e-15
 Identities = 80/339 (23%), Positives = 151/339 (43%), Gaps = 43/339 (12%)

Query: 13  GWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKL 72
           GW  +         L P +    G+  AE+G+L T  L+  ++    AG + D+ GR ++
Sbjct: 22  GWALDSFDMQMFSFLLPALTLTWGLTKAEVGVLGTVALVVTAIGGWGAGILSDRYGRARI 81

Query: 73  LTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRER-KGSALG 131
           L ++I+ ++L   L    + Y  L+  R L G   G  +A   AL++E+   R +G A+G
Sbjct: 82  LVLAIIWFTLFGVLAGFAQSYQQLLIARTLQGLGFGGEWAVGAALMAEVIDSRHRGKAIG 141

Query: 132 F----FMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKGEPIKVE 187
           F    F +G A+   +  L++  +   ++WR AF    I+ +++ + +   +K   +   
Sbjct: 142 FVQSGFALGWALAVVVATLLLAWLPKEMAWRVAFW-SGIIPALIVLFIRRHVKDSSMFER 200

Query: 188 GVKFKIPR----GVF------LLSLANFLGLG---AFFAMLTFLVSYLVSRGVGMEKASL 234
             + + PR     VF       L+L++ L +G     +A+L +L S L  R V      +
Sbjct: 201 ARQSRAPRASLSSVFNRKYARTLALSSVLVIGLQAGCYAILVWLPSLLNQRQVAAGSMIV 260

Query: 235 MFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYS 294
              +++     G  +   L D +G+   L+      LL+    ++     L+PL   L +
Sbjct: 261 TVFIMAFGSFCGFAVTADLSDRIGRRPTLI------LLSVCAWIVTVSYMLLPLNTTLTA 314

Query: 295 VGGIMTAYTSEKASRENLGVVMGFVNMVGFFGATIGPYI 333
           +                LG ++GF + +G F A +GP++
Sbjct: 315 I----------------LGFLVGF-SAIGMF-AALGPFL 335


>sp|P39637|YWFA_BACSU HYPOTHETICAL 44.5 KD PROTEIN IN ROCC-PTA INTERGENIC REGION
           >gi|629086|pir||S39734 chloramphenicol resistance
           homolog ywfA - Bacillus subtilis
           >gi|414003|emb|CAA51635.1| (X73124) ipa-79d [Bacillus
           subtilis] >gi|2636311|emb|CAB15802.1| (Z99123) alternate
           gene name: ipa-79d~similar to chloramphenicol resistance
           [Bacillus subtilis]
           Length = 412
           
 Score = 83.1 bits (202), Expect = 5e-15
 Identities = 83/393 (21%), Positives = 174/393 (44%), Gaps = 37/393 (9%)

Query: 4   LIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYI 63
           L++ + +++G     S  + +  L P + K     ++++ +L  S+ +   +I + A  +
Sbjct: 17  LLLALALTMGVFAAGSEELVISPLLPDLAKAF---SSDVSVLALSISIYGVMIFIGAPLL 73

Query: 64  ---GDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISE 120
              GDK  R+  L   ++ + + + +  L ++ +     RAL G  AG +   A A++ +
Sbjct: 74  VPLGDKYSRELSLLAGLMIFIIGTVICALAQNIFFFFLGRALSGLAAGAFVPTAYAVVGD 133

Query: 121 LFRER-KGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAI 179
                 +G  +G  +   ++       +   +   L WR+ F + ++M  +V +L+++ +
Sbjct: 134 RVPYTYRGKVMGLIVSSWSLALIFGVPLGSFIGGVLHWRWTFWIFALMGVLVVLLILLEM 193

Query: 180 KG-------------EPIKVEGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYLVSRG 226
           +              EP        K+PR    +++  F  +  F+ M +FL +YL    
Sbjct: 194 RRHAQHKNSGKEEIEEPAGTFRDALKVPRVPVYITIT-FCNMIGFYGMYSFLGTYLQDVF 252

Query: 227 VGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKV-SVLLAYALNSLLTFLVIVIPSPLFL 285
            G   A+ +F M+  +G   S+I G + D +GK+ S+L+A  + S+L   +   P+ +FL
Sbjct: 253 TGGNTAAGLFIMIYGIGFSMSVITGKIADRIGKMRSLLIALGVISVLLACLPYAPASMFL 312

Query: 286 IPLGLVLYSVGGIMTAYT-------SEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLI 338
           +   L ++   G+M + T           S  + G VM F ++      T+G  ++G + 
Sbjct: 313 LIASLFIW---GLMQSLTVTLLSTILSDCSERHRGKVMVFYSLASNLAVTLGSALMGPVY 369

Query: 339 DRLGYSLALLSVPLAYLVSAVIIGLDLRKTSYK 371
              GY+   L        +  ++G  L   +YK
Sbjct: 370 VAYGYAAVGL-----ICAAITVLGFVLSVFAYK 397


>sp|P42609|EXUT_ECOLI HEXURONATE TRANSPORTER >gi|7428805|pir||B65098 hexuronate
           transporter - Escherichia coli (strain K-12)
           >gi|1160319|dbj|BAA02588.1| (D13328) aldohexuronate
           transport system [Escherichia coli]
           >gi|2367193|gb|AAC76128.1| (AE000391) transport of
           hexuronates [Escherichia coli K12]
           Length = 472
           
 Score = 82.7 bits (201), Expect = 6e-15
 Identities = 82/398 (20%), Positives = 171/398 (42%), Gaps = 42/398 (10%)

Query: 6   ILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGD 65
           ++ L++LG +  Y  R  V + AP +M++L I+  +   ++ +    Y+++Q  AGY+ D
Sbjct: 51  MIALVTLGTVLGYLTRNTVAAAAPTLMEELNISTQQYSYIIAAYSAAYTVMQPVAGYVLD 110

Query: 66  KIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRER 125
            +G K    +  + +++      L   +  L   R   G              SE F  +
Sbjct: 111 VLGTKIGYAMFAVLWAVFCGATALAGSWGGLAVARGAVGAAEAAMIPAGLKASSEWFPAK 170

Query: 126 KGS-ALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMV------- 177
           + S A+G+F VG +IG+ I P +VV   +  SW+ AF++   +S I  +  ++       
Sbjct: 171 ERSIAVGYFNVGSSIGAMIAPPLVVWAIVMHSWQMAFIISGALSFIWAMAWLIFYKHPRD 230

Query: 178 -----------AIKGEPIKVE-GVKFKIPRGVFL-------LSLANFLGLGAFFAMLTFL 218
                       I G+  + +     K+  G  L       ++L  FL   A+     ++
Sbjct: 231 QKHLTDEERDYIINGQEAQHQVSTAKKMSVGQILRNRQFWGIALPRFLAEPAWGTFNAWI 290

Query: 219 VSYLVS-RGVGMEKASLMFSMLSLVGILGSIIAGF---LYDHLGKVSVLLAYALNSLLTF 274
             ++    G  +++ ++   M  L   LG I+ G+   L+     V+++++  +   L  
Sbjct: 291 PLFMFKVYGFNLKEIAMFAWMPMLFADLGCILGGYLPPLFQRWFGVNLIVSRKMVVTLGA 350

Query: 275 LVIVIPSPLFLIP---LGLVLYSVGGI--------MTAYTSEKASRENLGVVMGFVNMVG 323
           ++++ P  + L     + ++L  +GG         +   +S+   R  +    G   M  
Sbjct: 351 VLMIGPGMIGLFTNPYVAIMLLCIGGFAHQALSGALITLSSDVFGRNEVATANGLTGMSA 410

Query: 324 FFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVII 361
           +  +T+   +VG L D +G+S     + +  L+ A++I
Sbjct: 411 WLASTLFALVVGALADTIGFSPLFAVLAVFDLLGALVI 448


>sp|P42613|GARP_ECOLI PROBABLE GALACTARATE TRANSPORTER (D-GALACTARATE PERMEASE)
           >gi|7442469|pir||C65102 hypothetical 49.0 kD protein in
           rnpB-sohA intergenic region - Escherichia coli
           >gi|606067|gb|AAA57930.1| (U18997) ORF_f444 [Escherichia
           coli] >gi|1789515|gb|AAC76161.1| (AE000394) putative
           transport protein [Escherichia coli K12]
           Length = 444
           
 Score = 82.7 bits (201), Expect = 6e-15
 Identities = 88/413 (21%), Positives = 175/413 (42%), Gaps = 56/413 (13%)

Query: 3   KLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGY 62
           + +IL++I +    NY+ R  +      + K+L ++   +G + ++    Y L+Q+P G+
Sbjct: 16  RYLILLIIFIVTAVNYADRATLSIAGTEVAKELQLSAVSMGYIFSAFGWAYLLMQIPGGW 75

Query: 63  IGDKIGRKKLLTISILGYSLSSAL---IVLTRDYW---DLVTVRALYGFFAGLYYAPATA 116
           + DK G KK+ T S+  +SL + L   + +    W    +  +R + GF     +     
Sbjct: 76  LLDKFGSKKVYTYSLFFWSLFTFLQGFVDMFPLAWAGISMFFMRFMLGFSEAPSFPANAR 135

Query: 117 LISELF-RERKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILL 175
           +++  F  + +G+A   F         +   ++  +     W + F V+ ++  ++  L 
Sbjct: 136 IVAAWFPTKERGTASAIFNSAQYFSLALFSPLLGWLTFAWGWEHVFTVMGVIGFVLTALW 195

Query: 176 MVAIKGEP----IKVEGVKFKIPRGVFL---------------------LSLANFLGLGA 210
           +  I        +  E +KF    G  +                       L+N + LG 
Sbjct: 196 IKLIHNPTDHPRMSAEELKFISENGAVVDMDHKKPGSAAASGPKLHYIKQLLSNRMMLGV 255

Query: 211 FFA----------MLTFLVSYLV-SRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGK 259
           FF            LT+   YLV  +G+ + K  L+ S+ +L G  G ++ G   D+L K
Sbjct: 256 FFGQYFINTITWFFLTWFPIYLVQEKGMSILKVGLVASIPALCGFAGGVLGGVFSDYLIK 315

Query: 260 VSVLLAYA------LNSLLTFLVIVI----PSPLFLIPLGLVLY--SVGGIMTAYTSEKA 307
             + L  A      L  LL   +I+      + L ++ + L  +    G +     S+ A
Sbjct: 316 RGLSLTLARKLPIVLGMLLASTIILCNYTNNTTLVVMLMALAFFGKGFGALGWPVISDTA 375

Query: 308 SRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRL-GYSLALLSVPLAYLVSAV 359
            +E +G+  G  N+ G   + + P ++G+L+  L  ++ AL+ V  + L++ V
Sbjct: 376 PKEIVGLCGGVFNVFGNVASIVTPLVIGYLVSELHSFNAALVFVGCSALMAMV 428


>gb|AAA57897.1| (U18997) ORF_o472 [Escherichia coli]
           Length = 472
           
 Score = 82.3 bits (200), Expect = 8e-15
 Identities = 82/398 (20%), Positives = 171/398 (42%), Gaps = 42/398 (10%)

Query: 6   ILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGD 65
           ++ L++LG +  Y  R  V + AP +M++L I+  +   ++ +    Y+++Q  AGY+ D
Sbjct: 51  MIALVTLGTVLGYLTRNTVAARAPTLMEELNISTQQYSYIIAAYSAAYTVMQPVAGYVLD 110

Query: 66  KIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRER 125
            +G K    +  + +++      L   +  L   R   G              SE F  +
Sbjct: 111 VLGTKIGYAMFAVLWAVFCGATALAGSWGGLAVARGAVGAAEAAMIPAGLKASSEWFPAK 170

Query: 126 KGS-ALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMV------- 177
           + S A+G+F VG +IG+ I P +VV   +  SW+ AF++   +S I  +  ++       
Sbjct: 171 ERSIAVGYFNVGSSIGAMIAPPLVVWAIVMHSWQMAFIISGALSFIWAMAWLIFYKHPRD 230

Query: 178 -----------AIKGEPIKVE-GVKFKIPRGVFL-------LSLANFLGLGAFFAMLTFL 218
                       I G+  + +     K+  G  L       ++L  FL   A+     ++
Sbjct: 231 QKHLTDEERDYIINGQEAQHQVSTAKKMSVGQILRNRQFWGIALPRFLAEPAWGTFNAWI 290

Query: 219 VSYLVS-RGVGMEKASLMFSMLSLVGILGSIIAGF---LYDHLGKVSVLLAYALNSLLTF 274
             ++    G  +++ ++   M  L   LG I+ G+   L+     V+++++  +   L  
Sbjct: 291 PLFMFKVYGFNLKEIAMFAWMPMLFADLGCILGGYLPPLFQRWFGVNLIVSRKMVVTLGA 350

Query: 275 LVIVIPSPLFLIP---LGLVLYSVGGI--------MTAYTSEKASRENLGVVMGFVNMVG 323
           ++++ P  + L     + ++L  +GG         +   +S+   R  +    G   M  
Sbjct: 351 VLMIGPGMIGLFTNPYVAIMLLCIGGFAHQALSGALITLSSDVFGRNEVATANGLTGMSA 410

Query: 324 FFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVII 361
           +  +T+   +VG L D +G+S     + +  L+ A++I
Sbjct: 411 WLASTLFALVVGALADTIGFSPLFAVLAVFDLLGALVI 448


>pir||B83017 probable MFS transporter PA5030 [imported] - Pseudomonas aeruginosa
           (strain PAO1) >gi|9951319|gb|AAG08415.1|AE004916_4
           (AE004916) probable MFS transporter [Pseudomonas
           aeruginosa]
           Length = 438
           
 Score = 81.1 bits (197), Expect = 2e-14
 Identities = 87/362 (24%), Positives = 166/362 (45%), Gaps = 21/362 (5%)

Query: 24  VPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSLS 83
           +  + P++ K   I+ AE  L ++      +L  +  G I D IGRK ++ +S+L  +L 
Sbjct: 66  IQPMMPVLSKAFSISAAESSLALSVATAMLALGLLVTGPISDAIGRKPVMVVSLLAAALF 125

Query: 84  SALIVLTRDYWDLVTVRALYGF-FAGLYYAPATALISELFRERKGSALGFFMVGPAIGSG 142
           +    +   +  ++ +RAL G   +GL     T L  E+  +  G ++G ++ G AIG  
Sbjct: 126 TLGSAVMPTWHGVLLMRALVGLSLSGLAAVAMTYLSEEIHPQHIGLSMGLYIGGNAIGGM 185

Query: 143 ITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAI------KGEPIK----VEGVKFK 192
              LI   +   +SW  A  VL  ++ +  ++    +      +  P+K    + G +  
Sbjct: 186 SGRLISGVLVDFISWHAALAVLGGLALVAALVFWRVLPESKHFRPAPLKPATLLNGYRLH 245

Query: 193 I-PRGVFLLSLANFLGLGAFFAMLTFLVSYLVSRGVGMEKASL-MFSMLSLVGILGSIIA 250
               G+  L L  FL +G+F  +  ++   L++    M +A + + S++ L GI  S   
Sbjct: 246 FRDAGLPWLFLIGFLLMGSFVTLFNYIGYRLLAEPYHMSQAVVGVLSVVYLSGIYSSAWV 305

Query: 251 GFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSVG-----GIMTAYTSE 305
           G L D LG+  VL A  L  +L  L++ +  P+ L+  GL+L++ G      + +++   
Sbjct: 306 GSLADKLGRRKVLWAVIL-LMLGGLLLTLFEPIPLMLAGLLLFTFGFFGAHSVASSWIGR 364

Query: 306 KASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVIIGLDL 365
           +A R   G          + G+++   + G      G++   L +  + LV AV++ L L
Sbjct: 365 RALRAK-GQASSLYLFSYYVGSSLAGTLGGVFWHYYGWNGIGLFIG-SLLVVAVLVSLHL 422

Query: 366 RK 367
            +
Sbjct: 423 AR 424


>gi|11498923 multidrug resistance protein [Archaeoglobus fulgidus]
           >gi|7483887|pir||D69415 multidrug resistance protein
           homolog - Archaeoglobus fulgidus
           >gi|2649251|gb|AAB89920.1| (AE001012) multidrug
           resistance protein [Archaeoglobus fulgidus]
           Length = 371
           
 Score = 80.4 bits (195), Expect = 3e-14
 Identities = 86/365 (23%), Positives = 146/365 (39%), Gaps = 19/365 (5%)

Query: 7   LILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDK 66
           ++ + L   F Y+    V  + P     LG +            L  ++   P G + + 
Sbjct: 1   MLRLILSGFFAYASLSCVIPIIPSYASSLGASVFLSAFAAGVFALFPAIAMTPFGMLSEV 60

Query: 67  IGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRE-R 125
            GR++ L    +   L+S L + +     LV  R L+G  + LY     AL++++  E R
Sbjct: 61  YGRRRFLVAGAVTSLLASLLYLQSSTAELLVFSRTLHGLGSALYIPSINALVADISEESR 120

Query: 126 KGSALG--------FFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMV 177
           +G A+G         F  GP  G  ++    V     L+     LV S  + +  + +  
Sbjct: 121 RGEAMGKLQTALMLGFFAGPLAGGFVSDFFGVKAVFLLA-----LVFSAAALVPVVGVRE 175

Query: 178 AIKGEPIKVEGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVS-YLVSRGVGMEKASLMF 236
             KG  I   G +F  PR +  L    F+G+    ++  F +  Y     +  ++A L+ 
Sbjct: 176 RSKGGEI---GKQFIFPRKLAPLFAVMFVGMATGSSLALFAIPFYAPELNISQQQAGLLV 232

Query: 237 SMLSLVGILGSIIAGFLYDHLGK-VSVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSV 295
           ++L L   +  + AG L D  G+ V+ LL   +  L  F       P   +   L     
Sbjct: 233 AVLFLFSAIIRVPAGILADRAGRNVTALLGMVVTGLGLFSAFKPDFPFLFLASLLCGAGN 292

Query: 296 GGIMTAYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYL 355
           G + TA  +  +  EN G  MG  N V   G   G  + GF+   L +   +L +  A L
Sbjct: 293 GIVNTAVFAAASDYENRGYAMGVANTVLNAGIFAGTTLAGFMAGFLSFQSMMLILAAATL 352

Query: 356 VSAVI 360
           + + I
Sbjct: 353 LFSPI 357


>pir||T47026 hypothetical protein [imported] - Yersinia pestis
           >gi|4106614|emb|CAA21369.1| (AL031866) ORF46, len= 409
           aa, similar to many transport protein, eg: AEMML_1
           Ralstonia eutropha, (428 aa), 44.2 % identity in 407 aa
           overlap, Fasta scores: opt: 1217E(): 0, or U32790_4
           Haemophilus influenzae Rd section 1 (407 aa), 33.0%
           identity in 40>
           Length = 409
           
 Score = 80.4 bits (195), Expect = 3e-14
 Identities = 84/362 (23%), Positives = 155/362 (42%), Gaps = 27/362 (7%)

Query: 13  GWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKL 72
           GW  +    M    +   +M    I+  + G+L T  LL  ++    AG + D+ GR ++
Sbjct: 21  GWALDALDFMVFTFVIATLMALWQIDAGQAGMLSTVTLLFSAIGGWGAGILADRYGRVRI 80

Query: 73  LTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFR-ERKGSALG 131
           L I+IL +SL + LI   +++  +  +RAL G   G  +A  + L+ E+ R E +G A+G
Sbjct: 81  LQITILWFSLCTVLIGFAQNFEHVFILRALQGLGFGGEWAVGSVLMGEIVRAEHRGKAVG 140

Query: 132 FFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKGEPIKVEGVKF 191
               G AIG G   L+   +   LS  +A+  L  +  +  +L++   K  P     +K 
Sbjct: 141 TVQSGWAIGWGAAALLYTLMFSVLSEEWAWRALFWIGVLPALLVLYIRKNVPEPALFLKS 200

Query: 192 K-------------------IPRGVFLLSLANFLGLGAFFAMLTFLVSYL-VSRGVGMEK 231
           +                   + +   L SL      G ++A+ T+L ++L + R + +  
Sbjct: 201 RHEQQAKDRRVSSFAIFSPALLKTTVLASLLCTGVQGGYYAITTWLPTFLKLERNLSVIG 260

Query: 232 ASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLT---FLVIVIPSPLFLI-- 286
                 ++     +G I   +L D LG+ + L+ ++L S +T   +  + + +   L+  
Sbjct: 261 TGGYLMVIIFGSFVGYICGAYLTDKLGRRANLIIFSLLSCITIFAYTQLTLTNTQMLVLG 320

Query: 287 -PLGLVLYSVGGIMTAYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYSL 345
            PLG     +   M A+ +E           GF    G     + P +VG+L      + 
Sbjct: 321 FPLGFSASGIFSGMGAFLTELFPSAVRATGQGFTYSFGRAVGALFPGLVGYLSQSSSLAF 380

Query: 346 AL 347
           A+
Sbjct: 381 AI 382


>sp|P39398|YJJL_ECOLI HYPOTHETICAL 49.4 KD PROTEIN IN TSR-MDOB INTERGENIC REGION
           >gi|7428806|pir||F65250 hypothetical 49.4 kD protein in
           tsr-mdoB intergenic region - Escherichia coli
           >gi|2367379|gb|AAC77312.1| (AE000506) putative transport
           protein, cryptic, orf, joins former yjiZ and yjjL
           [Escherichia coli K12]
           Length = 453
           
 Score = 80.4 bits (195), Expect = 3e-14
 Identities = 86/395 (21%), Positives = 166/395 (41%), Gaps = 65/395 (16%)

Query: 7   LILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDK 66
           ++L+    + NY  R ++      I ++LG++  EIG L++   L Y + Q+P G + D+
Sbjct: 44  MLLLFFAAVINYLDRSSLSVANLTIREELGLSATEIGALLSVFSLAYGIAQLPCGPLLDR 103

Query: 67  IGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFR-ER 125
            G + +L + +  +SL  A+  +  ++   V VR   G            +I++ F  + 
Sbjct: 104 KGPRLMLGLGMFFWSLFQAMSGMVHNFTQFVLVRIGMGIGEAPMNPCGVKVINDWFNIKE 163

Query: 126 KGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGI-LLMVAIKGEPI 184
           +G  +GFF     IG  ++P I+  + L + WR  F+ + ++   + I   M+    E +
Sbjct: 164 RGRPMGFFNAASTIGVAVSPPILAAMMLVMGWRGMFITIGVLGIFLAIGWYMLYRNREHV 223

Query: 185 KVEGVK-----------------FKIPRGVFLL-----SLANFLGLG-AFFAMLTFLVSY 221
           ++  V+                 F   R +F        +  F G+    +  L +L  Y
Sbjct: 224 ELTAVEQAYLNAGSVNARRDPLSFAEWRSLFRNRTMWGMMLGFSGINYTAWLYLAWLPGY 283

Query: 222 L-VSRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHL----------GKVSVLLAYALNS 270
           L  +  + ++   LM ++  L G  G ++ G++ D L           K+ ++     ++
Sbjct: 284 LQTAYNLDLKSTGLMAAIPFLFGAAGMLVNGYVTDWLVKGGMAPIKSRKICIIAGMFCSA 343

Query: 271 LLTFL----------VIVIPSPLFLIPL------GLVLYSVGGIMTAYTSEKASRENLGV 314
             T +          V++I   LF I        GL+  +V   MTA         ++G 
Sbjct: 344 AFTLIVPQATTSMTAVLLIGMALFCIHFAGTSCWGLIHVAVASRMTA---------SVGS 394

Query: 315 VMGFVNMVGFFGATIGPYIVGFLIDRL-GYSLALL 348
           +  F +   F  A+  P I GF++D    + LAL+
Sbjct: 395 IQNFAS---FICASFAPIITGFIVDTTHSFRLALI 426


>pir||D75358 probable fosmidomycin resistance protein - Deinococcus radiodurans
           (strain R1) >gi|6459517|gb|AAF11300.1|AE002016_2
           (AE002016) fosmidomycin resistance protein, putative
           [Deinococcus radiodurans]
           Length = 409
           
 Score = 80.0 bits (194), Expect = 4e-14
 Identities = 82/379 (21%), Positives = 162/379 (42%), Gaps = 34/379 (8%)

Query: 6   ILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGD 65
           I + ++ G   N ++   +  L P +    G+  A + LL +   L  S++Q   G +G+
Sbjct: 36  IALAVTAGHFINDAYGAMLTPLTPALQSKYGVTIAAVTLLSSVFSLTSSVLQPLLGIVGE 95

Query: 66  KIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELF-RE 124
           +I R+    +  L   +   L+     +  L+ + A+ GF +G ++   +A +++    +
Sbjct: 96  RIDRRYAAALGPLMTGVGLTLMGFVPWFGALILLVAVAGFGSGFFHPAGSAYVAQNSPAD 155

Query: 125 RKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKGEPI 184
           ++G     F  G   G  + P+        L W       +++ +++  +  V       
Sbjct: 156 KRGLWASIFSAGGTAGMALGPVFAGVGLTHLPW------FALIGAVIAAVTFVVTPSGAQ 209

Query: 185 KVEGVKFKIPRGVFLLSLANFLGLG--------AFFAMLTFLVSYLVSRGVGMEKASLMF 236
           K + V      G+F   L    G+          + AML F+   L++RG G  +     
Sbjct: 210 KAKRVGLAEYAGIFRGPLVWLWGMAVLRSLASMGYNAMLPFM---LMARGFGAREVGTTL 266

Query: 237 SMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPL--FLIPLGLVLYS 294
           ++ ++    G I+ G L D  G+  VL A  L+++  F V+++ SP   +  PL    ++
Sbjct: 267 AIYAVASAFGGILGGRLSDKYGRTPVLRAAILSTIPFFAVLILSSPADWWFYPL---TFA 323

Query: 295 VGGIMTA------YTSEKASRENLGVVMGFVNMVGFFGATIG--PYIVGFLIDRLGYSLA 346
           VG  + A       T+++ + +++ V      M+GF     G   ++VG L D      A
Sbjct: 324 VGAAVNASIPVGVVTAQEYAPQHVAVASSI--MMGFSWGIAGVLVFVVGALADVTTPQTA 381

Query: 347 LLSVPLAYLVSAVIIGLDL 365
            L+  LA L+ + +I   L
Sbjct: 382 ALA-SLALLIPSALIAYRL 399


>pir||D72302 hypothetical protein TM1021 - Thermotoga maritima (strain MSB8)
           >gi|2695718|emb|CAA04933.1| (AJ001694) putative membrane
           protein [Thermotoga maritima]
           >gi|4981562|gb|AAD36098.1|AE001764_1 (AE001764)
           permease, putative [Thermotoga maritima]
           Length = 422
           
 Score = 79.6 bits (193), Expect = 5e-14
 Identities = 96/404 (23%), Positives = 169/404 (41%), Gaps = 53/404 (13%)

Query: 1   MEKLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPA 60
           M  + ILIL+ L    N    +  P++  I  ++  I +A+IGL+ +S  +  +L+ +  
Sbjct: 1   MAVIFILILMVL---LNADQMVMSPNIGAI-EQEFNITDAQIGLVASSFTVIGALVSLVW 56

Query: 61  GYIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISE 120
           GY+ D+  RK LL  SIL   +   +   +R Y +L   RAL G   G  +    ++I +
Sbjct: 57  GYLADRYSRKNLLIYSILVGEIPCLMSAFSRSYGELFFWRALTGIGVGASFPIVYSMIGD 116

Query: 121 LFRE-RKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAI 179
           +F E ++G  +       +IGS +  ++   +     WR  F+ +S+ +    +L +  +
Sbjct: 117 MFDEVKRGKVVALISSAISIGSVLGMIVGGFLGPKYGWRVPFIAVSVPNIFFAVLSIFVL 176

Query: 180 K-----------GEPIK--------------VEGVKFKIPRGVFLLSLANFLGLGAFFAM 214
           K           GE ++               + VK K    +F   +A  +  G   A+
Sbjct: 177 KEPKRGAFEKGIGELVQSGYEYPKAPKLSDYAKLVKVKTNLLLFFQGIAGTIPWG---AI 233

Query: 215 LTFLVSYL-VSRGVGMEKASLMFSMLSLVGILGSIIAGF----LYDHLGKVSVLLAYALN 269
             FLV +    RG+ +E A+L+F +  L  I+G I+ G     +Y        L      
Sbjct: 234 PYFLVEFFRRERGLSVETATLVFLVFGLGNIVGIILGGLWGASIYAKSRPFLPLFCSITT 293

Query: 270 SLLTFLVIV----IPSPLFLIPLGLVLYSVGGI-------MTAYTSEKASRENLGVVMGF 318
           +L TF  ++    + S L L+ LG +      +       M    +E   R   G +   
Sbjct: 294 ALGTFFTVMTLDYMGSLLVLMLLGFIASFTASLTGPNVKFMLLNVNEPQER---GRIFSI 350

Query: 319 VNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAY-LVSAVII 361
            N+    G   G +  G +   LG   A L V   + L+ AV++
Sbjct: 351 FNLTDSLGTGFGKFAGGVMSVALGSLGAALKVSAYFWLICAVLL 394


>gb|AAF58060.1| (AE003808) CG8428 gene product [Drosophila melanogaster]
           Length = 552
           
 Score = 79.6 bits (193), Expect = 5e-14
 Identities = 79/365 (21%), Positives = 148/365 (39%), Gaps = 44/365 (12%)

Query: 15  IFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLT 74
           + NY  R  +  +   +  D  I N   GLL T  ++ Y +     GY+GD+  R  ++ 
Sbjct: 125 LINYMDRFTIAGVLTDVRNDFDIGNDSAGLLQTVFVISYMVCAPIFGYLGDRYSRPWIMA 184

Query: 75  ISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELF-RERKGSALGFF 133
           + +  +S ++ L    + +   +  RAL G     Y   A  +IS+LF  + +   L  F
Sbjct: 185 VGVGLWSTTTLLGSFMKQFGWFIAFRALVGIGEASYSTIAPTIISDLFVHDMRSKMLALF 244

Query: 134 MVGPAIGSGITPLIVVPVA-LTLSWRYAFLVLSIMSSIVGILLMVAIKGEPIK------- 185
                +GSG+  ++    A L   WR+A  V  I+  IV + L++ IK +P++       
Sbjct: 245 YFAIPVGSGLGYIVGSKTAHLANDWRWALRVTPIL-GIVAVFLILLIK-DPVRGHSEGSH 302

Query: 186 -------VEGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYLVSRGVGME-------- 230
                   + +K  +    F+LS A F  +      L +     +  G+ M+        
Sbjct: 303 NLEATTYKQDIKALVRNRSFMLSTAGFTCVAFVAGALAWWGPSFIYLGMKMQPGNENIVQ 362

Query: 231 -----KASLMFSMLSLVGI-LGSIIAGFL---YDHLGKVSVLLAYALNSLLTFLVIVIPS 281
                K  L+  +  L+G+ LGS +A  L   Y++       +   +++ + F  +V+P 
Sbjct: 363 DDISYKFGLVAMLAGLIGVPLGSFLAQRLRGRYENCDPYICAVGLFISAPMVFAALVVPQ 422

Query: 282 P------LFLIPLGLVLYSVGGIMTAYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVG 335
                   F+    + L     I+      +    N GV+     + G  G  +G ++  
Sbjct: 423 TSESLCFFFVFVAQVALNLCWSIVADILLVRCVAFNFGVI---TMLAGLLGVPLGSFLSQ 479

Query: 336 FLIDR 340
           +L+ R
Sbjct: 480 YLVKR 484


>gb|AAK41596.1| Transport membrane protein (permease) [Sulfolobus solfataricus]
           Length = 374
           
 Score = 79.2 bits (192), Expect = 7e-14
 Identities = 74/363 (20%), Positives = 159/363 (43%), Gaps = 14/363 (3%)

Query: 10  ISLGWIFNYSH---RMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDK 66
           I +GWI  +     R++   ++  I     +N+ +IGL+ T+  + Y L  +P G I D+
Sbjct: 5   IIVGWIGTFLQLFLRLSWGVISLPIALLFHLNSIQIGLVATAFYIGYVLSSIPWGLIIDR 64

Query: 67  IGRKKLLT-ISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRER 125
           IG  + +   SI+   ++  L +   DY  L+    + G      +  A  +++  +   
Sbjct: 65  IGPSRAVEYASIILVGMNLLLFLYLTDYTILLIAYLIEGLITASIFPSAMKIVAVSYSHS 124

Query: 126 KGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGIL---LMVAIKGE 182
                   +V  A    I  L ++   L   WR+ +L +++   ++ IL     +++ G 
Sbjct: 125 SKFTFYVALVESAGPITIITLGIIASFLLHLWRFIYLAMAVSFGLIAILSHFSRISVSGT 184

Query: 183 PIKVEGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYLV-SRGVGMEKASLMFSMLSL 241
            IK    +  + R + + +L     L + +   T++   LV  RG+    ++L   +  +
Sbjct: 185 EIK-RSFRVILNRKITMATLVRLGELWSTWGTTTWIFPMLVLYRGISPTLSALFLLLFGV 243

Query: 242 VGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIP----LGLVLYSVGG 297
             ++G +    L +  G  +V+L   +  ++   +I+  + + ++P    LG+  +S   
Sbjct: 244 GQLVGILSVEKLVERFGDSNVILINLIGFIILTFLIIFSNDIDILPEAFLLGIFSFSYRP 303

Query: 298 IMTAYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRL-GYSLALLSVPLAYLV 356
              +   + A   + G  +GF N V   G  I P  VG ++     +S+++L++    ++
Sbjct: 304 PTDSLIMKIAGESSAGTSIGFANAVSQIGTMIAPSFVGLVLYLTHSFSISMLALDAGCVI 363

Query: 357 SAV 359
           S V
Sbjct: 364 SIV 366


>sp|P37948|GLPT_BACSU GLYCEROL-3-PHOSPHATE TRANSPORTER (G-3-P TRANSPORTER) (G-3-P
           PERMEASE) >gi|2119807|pir||I40417 glycerol-3-phosphate
           transport protein glpT - Bacillus subtilis
           >gi|403372|emb|CAA81291.1| (Z26522) glycerol 3-phosphate
           permease [Bacillus subtilis] >gi|2632500|emb|CAB12008.1|
           (Z99105) glycerol-3-phosphate permease [Bacillus
           subtilis] >gi|3599636|dbj|BAA33111.1| (AB006424) ybeE
           [Bacillus subtilis]
           Length = 444
           
 Score = 78.4 bits (190), Expect = 1e-13
 Identities = 79/408 (19%), Positives = 170/408 (41%), Gaps = 48/408 (11%)

Query: 3   KLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGY 62
           +L + I I +G+   Y  R       P + +  G +  E+GL++ ++ + Y   +   G 
Sbjct: 27  RLQVFIGIFIGYAGYYLLRKNFAFAIPYLQEQ-GFSKTELGLVLAAVSIAYGFSKFIMGM 85

Query: 63  IGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALY----GFFAGLYYAPATALI 118
           + D+   +  L   +   ++ + L V        VT+  ++    G+F G+ + P    +
Sbjct: 86  VSDRCNPRYFLATGLFLSAIVNILFVSMPWVTSSVTIMFIFMFINGWFQGMGWPPCGRTM 145

Query: 119 SELFR-ERKGSALGFFMVGPAIGSGI-TPLIVVPVALTLSWRYAFLVLSIMSSIVGILLM 176
           +  F    +G+ +  + V   IG GI  PL+ + +A+ ++W+  F   +I++ I+  L++
Sbjct: 146 AHWFSISERGTKMSIWNVAHNIGGGILAPLVTLGIAMFVTWKSVFFFPAIIAIIISFLIV 205

Query: 177 VAIKGEPIK-----VEGVKFKIPRGVF---------------LLSLANFLGLGAFFAMLT 216
           + ++  P       +E  +   P+  F                +    FL   AF  +  
Sbjct: 206 LLVRDTPQSCGLPPIEEYRNDYPKHAFKNQEKELTTKEILFQYVLNNKFLWYIAFANVFV 265

Query: 217 FLVSYLV----------SRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAY 266
           + V Y V          ++G   E +   + +    GI G+I+ G++ D   K     A 
Sbjct: 266 YFVRYGVVDWAPTYLTEAKGFSPEDSRWSYFLYEYAGIPGTILCGWISDRFFKSRRAPAG 325

Query: 267 ALNSLLTFLVIVI------PSPLF----LIPLGLVLYSVGGIMTAYTSEKASRENLGVVM 316
            L     F+ +++       +PL     LI +G ++Y    ++     + A ++  G   
Sbjct: 326 VLFMAGVFIAVLVYWLNPAGNPLVDNIALISIGFLIYGPVMLIGLQAIDLAPKKAAGTAA 385

Query: 317 GFVNMVGFF-GATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVIIGL 363
           G     G+  G+     I+GF++DR  ++   + +  + +++ V + L
Sbjct: 386 GLTGFFGYIGGSAFANAIMGFVVDRFNWNGGFIMLISSCILAIVFLAL 433


>sp|P46907|NARK_BACSU NITRITE EXTRUSION PROTEIN (NITRITE FACILITATOR)
           >gi|2127151|pir||S60080 nitrite extrusion protein narK -
           Bacillus subtilis >gi|971337|emb|CAA90041.1| (Z49884)
           nitrite extrusion protein [Bacillus subtilis]
           >gi|2636269|emb|CAB15760.1| (Z99123) nitrite extrusion
           protein [Bacillus subtilis] >gi|1586090|prf||2203266A
           dissimilatory nitrate reductase [Bacillus subtilis]
           Length = 395
           
 Score = 78.4 bits (190), Expect = 1e-13
 Identities = 81/374 (21%), Positives = 159/374 (41%), Gaps = 23/374 (6%)

Query: 5   IILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIG 64
           I L L SL  +  +   + + SL   I  D+ ++  EI L+    ++  SL+++P GY+ 
Sbjct: 7   IQLSLQSLSLVAGFMVWVLISSLISQITLDIHLSKGEISLVTAIPVILGSLLRIPLGYLT 66

Query: 65  DKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRE 124
           ++ G + +  +S +        I +    +DL+      G    ++    T+L     +E
Sbjct: 67  NRFGARLMFMVSFILLLFPVFWISIADSLFDLIAGGFFLGIGGAVFSIGVTSLPKYYPKE 126

Query: 125 RKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKGEPI 184
           + G   G +  G  IG+ +T      +A  + W+    +  I+ ++  +L ++       
Sbjct: 127 KHGVVNGIYGAG-NIGTAVTTFAAPVIAQAVGWKSTVQMYLILLAVFALLHVLFGDRHEK 185

Query: 185 KVE-GVKFKIP-----RGVFLLSLANFLGLGAFFAMLTFLVSYLVSR-GVGMEKASLMFS 237
           KV+  VK +I        ++ LSL  F+  GAF A   +L ++LV   G+    A L  +
Sbjct: 186 KVKVSVKTQIKAVYRNHVLWFLSLFYFITFGAFVAFTIYLPNFLVEHFGLNPADAGLRTA 245

Query: 238 MLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSVGG 297
               V  L     GFL D +  + +L+       L+ +++     + L   G +  +V  
Sbjct: 246 GFIAVSTLLRPAGGFLADKMSPLRILMFVFTGLTLSGIILSFSPTIGLYTFGSLTVAVCS 305

Query: 298 ---------IMTAYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLG-YSLAL 347
                    ++  Y S++A     G+  G V+ +G  G    P I+  +    G Y++  
Sbjct: 306 GIGNGTVFKLVPFYFSKQA-----GIANGIVSAMGGLGGFFPPLILASVFQATGQYAIGF 360

Query: 348 LSVPLAYLVSAVII 361
           +++    L S V++
Sbjct: 361 MALSEVALASFVLV 374


>dbj|BAB13277.1| (AP001119) hypothetical protein [Buchnera sp. APS]
           Length = 410
           
 Score = 78.0 bits (189), Expect = 2e-13
 Identities = 85/388 (21%), Positives = 176/388 (44%), Gaps = 28/388 (7%)

Query: 5   IILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIG 64
           +IL L S G+   +S    V S+ P+  K   +  AE  L +++  +  SL  +  G + 
Sbjct: 26  VILALFSGGFA-TFSILYCVQSILPMFSKQFYLTPAESSLALSAATITMSLGMLFTGPLS 84

Query: 65  DKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGF-FAGLYYAPATALISELFR 123
           D IGRK +++ S+   ++ + +  +   +  +V +RAL G   +G+     T +  E+  
Sbjct: 85  DIIGRKSIMSTSLFIAAMLTMICSMMTSWISIVLLRALTGLALSGVVAVAMTYISEEIHP 144

Query: 124 ERKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGI---------- 173
                 +G ++ G  IG  +  L+   +A   SW  + +V+ + S I             
Sbjct: 145 NSLSFCMGLYISGNTIGGFLGRLLSSILAEKFSWSISLMVIGLFSFISSCFFLYFLPPSK 204

Query: 174 -LLMVAIKGEPIKVEGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYLVSRGVGMEKA 232
             L V+I               R +F L +  F+ +G+F  +  ++   L+     + ++
Sbjct: 205 NFLSVSINFHKCLHRFYLQLKNRVLFFLFIIGFILMGSFVTIFNYIGYRLMLEPFFLCQS 264

Query: 233 SL-MFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIPLGLV 291
           S+ + S + L G+  S  AG L +   + ++L+  +L  ++  L I   + LF+I LGL+
Sbjct: 265 SIGLLSTIYLTGVYSSPKAGVLINKYNRNNILIV-SLMLMIIGLFITQYNQLFIIILGLI 323

Query: 292 LYSVGGIMTAYTSEKA---SRENLGVVMGFVNMVGFF--GATIGPYIVGFL---IDRLGY 343
           ++S GG   ++++  +   S  N+  +      + F+  G+++     GF    +  LG 
Sbjct: 324 IFS-GGFFASHSTASSWVGSYSNIAKIQATSLYLFFYYLGSSVFGTFGGFFWFHMQWLGI 382

Query: 344 SLALLSVPLAYLVSAVIIGLDLRKTSYK 371
           S+ ++++    L   V +   L++ ++K
Sbjct: 383 SVFIITM----LFFGVFLSFKLKQKNFK 406


>gb|AAA16158.1| (M80252) norA1199 protein [Staphylococcus aureus]
           >gi|153055|gb|AAA26658.1| (M97169) norA [Staphylococcus
           aureus]
           Length = 388
           
 Score = 77.6 bits (188), Expect = 2e-13
 Identities = 85/366 (23%), Positives = 167/366 (45%), Gaps = 41/366 (11%)

Query: 1   MEKLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPA 60
           M K I+++  ++  IF     + +P L P+ +KDLG+  +++GLL+ +  L   +I    
Sbjct: 1   MNKQILVLYFNIFLIF-LGIGLVIPVL-PVYLKDLGLTGSDLGLLVAAFALSQMIISPFG 58

Query: 61  GYIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISE 120
           G + DK+G+K ++ I ++ +S+S  +  + +++  L+  R + G  AG+     T LI++
Sbjct: 59  GTLADKLGKKLIICIGLILFSVSEFMFAIGQNFLILMLSRVIGGMSAGMVMPGVTGLIAD 118

Query: 121 LF-RERKGSALGF--------FMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIV 171
           +    +K    G+        F++GP IG       +  V+  + + +A   L I++ I+
Sbjct: 119 ISPSHQKAKNFGYMSAIINSGFILGPGIGG-----FMAEVSHRMPFYFAG-ALGILAFIM 172

Query: 172 GILLM-----VAIKG----EPIKVEGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYL 222
            I+L+     V+  G    EP  +  + +K+     +L+L    GL AF      L S  
Sbjct: 173 SIVLIHDPKKVSTNGFQKLEPQLLTKINWKVFITPVILTLVLSFGLSAF----ETLYSLY 228

Query: 223 VSRGVGMEKASLMFSMLSLVGILGSIIAGFLYD----HLGKVSVLLAYALNSLLTFLVIV 278
            +  V      +  ++    GI G++   + +D    +  +++ +    + S++  +++V
Sbjct: 229 TADKVNYSPKDISIAITG-GGIFGALFQIYFFDKFMKYFSELTFIAWSLIYSVIVLVLLV 287

Query: 279 IPSPLFLIPLGLVLYSVGGIM-----TAYTSEKASRENLGVVMGFVNMVGFFGATIGPYI 333
           I    + I +   +  +G  M     T Y S  A  +  G   G  +     G  IGP I
Sbjct: 288 IADGYWTIMVISFVVFIGFDMIRPAITNYFSNIAG-DRQGFAGGLNSTFTSMGNFIGPLI 346

Query: 334 VGFLID 339
            G L D
Sbjct: 347 AGALFD 352


>sp|Q46916|GUDP_ECOLI PROBABLE GLUCARATE TRANSPORTER (D-GLUCARATE PERMEASE)
           >gi|7442470|pir||A65061 hypothetical protein b2789 -
           Escherichia coli >gi|882684|gb|AAB40439.1| (U29581)
           ORF_f450 [Escherichia coli] >gi|1789152|gb|AAC75831.1|
           (AE000362) putative transport protein [Escherichia coli
           K12]
           Length = 450
           
 Score = 77.6 bits (188), Expect = 2e-13
 Identities = 86/427 (20%), Positives = 184/427 (42%), Gaps = 63/427 (14%)

Query: 6   ILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGD 65
           I++++ +   FNY  R  +      + KD+G++   +G + ++    Y + Q+P G++ D
Sbjct: 21  IVVMLFIVTSFNYGDRATLSIAGSEMAKDIGLDPVGMGYVFSAFSWAYVIGQIPGGWLLD 80

Query: 66  KIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALY--GFFAGLYYAPA----TALIS 119
           + G K++   SI  +S+ + L      +     + AL+   F  GL  AP+    + +++
Sbjct: 81  RFGSKRVYFWSIFIWSMFTLLQGFVDIFSGFGIIVALFTLRFLVGLAEAPSFPGNSRIVA 140

Query: 120 ELF-RERKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVA 178
             F  + +G+A+  F       + I   I+  +   + W + F  +  +  ++  + +  
Sbjct: 141 AWFPAQERGTAVSIFNSAQYFATVIFAPIMGWLTHEVGWSHVFFFMGGLGIVISFIWLKV 200

Query: 179 IKGEPIKVEGV----------------------KFKIPRGVFLLSLANFLG----LGAF- 211
           I  EP +  GV                      K K+P  V    +   LG    +G + 
Sbjct: 201 IH-EPNQHPGVNKKELEYIAAGGALINMDQQNTKVKVPFSVKWGQIKQLLGSRMMIGVYI 259

Query: 212 ---------FAMLTFLVSYLV-SRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHL---- 257
                    +  +T+   YLV +RG+ + KA  + S+ ++ G +G ++ G + D L    
Sbjct: 260 GQYCINALTYFFITWFPVYLVQARGMSILKAGFVASVPAVCGFIGGVLGGIISDWLMRRT 319

Query: 258 ------GKVSVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLY--SVGGIMTAYTSEKASR 309
                  K  +++   L+ ++ F   V    + +  + L  +   +G +  A  ++ A +
Sbjct: 320 GSLNIARKTPIVMGMLLSMVMVFCNYVNVEWMIIGFMALAFFGKGIGALGWAVMADTAPK 379

Query: 310 ENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLG-YSLALLSVPLAYLVSA----VIIGLD 364
           E  G+  G  NM G     + P  +G+++   G ++ AL+ V +  L++     V++G D
Sbjct: 380 EISGLSGGLFNMFGNISGIVTPIAIGYIVGTTGSFNGALIYVGVHALIAVLSYLVLVG-D 438

Query: 365 LRKTSYK 371
           +++   K
Sbjct: 439 IKRIELK 445


>pir||A64668 chloramphenicol resistance protein homolog HP1185 - Helicobacter
           pylori (strain 26695) >gi|2314345|gb|AAD08231.1|
           (AE000624) conserved hypothetical integral membrane
           protein [Helicobacter pylori 26695]
           Length = 391
           
 Score = 77.3 bits (187), Expect = 3e-13
 Identities = 67/297 (22%), Positives = 136/297 (45%), Gaps = 22/297 (7%)

Query: 14  WIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLL 73
           +IFN +  + V  L+ I  K   + +A +GL++T+     SL  +P   +  KI RK+LL
Sbjct: 24  FIFNTTEFVPVALLSDIA-KSFEMESATVGLMITAYAWVVSLGSLPLMLLSAKIERKRLL 82

Query: 74  TISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELF-RERKGSALGF 132
                 + LS  L  L  ++W L+  R    F   ++++   +L+  +  R +K  ALG 
Sbjct: 83  LFLFALFILSHILSALAWNFWVLLLSRMGIAFAHSIFWSITASLVIRVAPRNKKQQALGL 142

Query: 133 FMVGPAIGSGITPLIVVP----VALTLSWRYAFLVLSIMSSIVGILLMVAIKGEPIKVEG 188
                A+GS +  ++ +P    +   L WR  F V+  +++++ +L+   +   P +  G
Sbjct: 143 L----ALGSSLAMILGLPLGRIIGQILDWRSTFGVIGGVATLIALLMWKLLPHLPSRNAG 198

Query: 189 VKFKIP--------RGVFLLSLANFLGLGAFFAMLTFLVSYLVS-RGVGMEKASLMFSML 239
               +P         G++LL +   + +   F   +++  +++       +  +LM  + 
Sbjct: 199 TLASVPVLMKRPLLMGIYLLVI---MVISGHFTTYSYIEPFIIQISQFSPDITTLMLFVF 255

Query: 240 SLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSVG 296
            L G++GS + G LY    +  +  A  L      L+ V  +  +++ L + L+ +G
Sbjct: 256 GLAGVVGSFLFGRLYAKNSRKFIAFAMVLVICPQLLLFVFKNLEWVVFLQIFLWGIG 312


>emb|CAC13963.1| (AJ012115) multidrug efflux transporter [Listeria monocytogenes]
           Length = 392
           
 Score = 77.3 bits (187), Expect = 3e-13
 Identities = 82/364 (22%), Positives = 153/364 (41%), Gaps = 21/364 (5%)

Query: 24  VPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSLS 83
           V  L P I + +G +++++ +L T+ +   +++ +P G +  K+G  KL+ I +   ++ 
Sbjct: 22  VDPLLPSIAESIGASHSQVEMLFTAYIFTMAIMMIPIGIVAGKMGYIKLIVIGLFIVTIF 81

Query: 84  SALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRERKGSALGFFMVGPAIGSGI 143
           + L  L+     L   RA +GF   ++ A A  ++  L R R G A+G +     +    
Sbjct: 82  ALLCGLSDTIGALSIFRAGWGFGNSMFMATAMTMLIALSRPR-GHAIGIYEASMGLEMAF 140

Query: 144 TPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKGEPIKV-----EGVKFKIPRGVF 198
            PL+   +   +SWRY     + +  I  +L++  +K EP KV     E  +  I + + 
Sbjct: 141 GPLL-GGILGNISWRYPCFATACLIFIAFLLILFKVK-EPKKVAPAPREKNEVAIKQMLH 198

Query: 199 LLSLANFLGLG--------AFFAMLTF--LVSYLVSRGVGMEKASLMFSMLSLV--GILG 246
           L     FL +          FF +L +  LV +L+S         L   +  LV   +  
Sbjct: 199 LFKYRPFLQIAFSGMFYYYCFFTILAYSPLVPWLISNSNWFCIFCLGIMLWHLVQRKVSH 258

Query: 247 SIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSVGGIMTAYTSEK 306
           ++   F    + K S+L    + +LL F+         ++  GL+L     + T    E 
Sbjct: 259 ALEIRFNSKQILKGSLLACAVILALLGFIDNTAVDIGLIVISGLILGINNALFTTTVMEH 318

Query: 307 ASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVIIGLDLR 366
           +      V  G  N V + GA   P   G L + LG  +  +   +  L    ++ + L+
Sbjct: 319 SPYAR-SVTSGAYNFVRWLGAAFAPLCSGLLSEALGMKMPFIVASIICLAGMGLLFIKLK 377

Query: 367 KTSY 370
              +
Sbjct: 378 PAHF 381


>gb|AAG34371.1|AF197465_3 (AF197465) putative nitrate/nitrite transporter; NarD [Pseudomonas
           fluorescens]
           Length = 421
           
 Score = 77.3 bits (187), Expect = 3e-13
 Identities = 86/370 (23%), Positives = 155/370 (41%), Gaps = 34/370 (9%)

Query: 5   IILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIG 64
           ++L + +L +   +   M    L   I + L +N  + GLL  + +L  SL+++P G + 
Sbjct: 9   LVLGMSTLAFTVCFMVWMMFAVLGVPIKELLALNETQFGLLAATPVLTGSLVRLPLGLLT 68

Query: 65  DKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELF-R 123
           D+ G + +  + +L   L   LI L   YW  + V  L+   AG  ++   A +++ F +
Sbjct: 69  DRFGGRIVFFLLMLACVLPLYLITLATAYWQFL-VLGLFVGLAGGSFSVGIAYVAKWFDK 127

Query: 124 ERKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGIL--LMVAIKG 181
           + +G A+G F  G A G+ +T  +   +    +W     V S +  I  +L   + A K 
Sbjct: 128 QNQGFAMGVFGAGNA-GAAVTKFLAPALIAFGTWHLVPKVFSAILFITALLFWFLTAEKK 186

Query: 182 EPIKVEG------VKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYLVSR-GVGMEKASL 234
           E     G      +K      V+       +  G + A+  ++  Y V   G  ++ A+L
Sbjct: 187 EHRNAGGATLREQLKSLKDPAVWRYCQYYSIVFGGYVALALWMTKYYVQEYGFSLQSAAL 246

Query: 235 MFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIPL--GLVL 292
           + +  SL G +   + G++ D  G  SV       S +   ++  P     +    G+V 
Sbjct: 247 LAACFSLPGGVLRAVGGWMSDRWGAQSVTWWVLWVSWICLFLLSYPQTQLQVQTVNGIVD 306

Query: 293 YSVGGIMT-----------AYTSEKAS---------RENLGVVMGFVNMVGFFGATIGPY 332
           + +G   T           A+   KAS          +N+G V G V + G  G  + P 
Sbjct: 307 FHIGLNATLFPVILFVMGIAFAFGKASVFKYIANNYPQNMGAVSGIVGLAGGLGGFVLPI 366

Query: 333 IVGFLIDRLG 342
           + G L+D  G
Sbjct: 367 MFGALVDLTG 376


>dbj|BAA36484.1| (AB019536) NorA [Staphylococcus aureus]
           Length = 388
           
 Score = 76.9 bits (186), Expect = 4e-13
 Identities = 84/366 (22%), Positives = 167/366 (44%), Gaps = 41/366 (11%)

Query: 1   MEKLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPA 60
           M K I ++  ++  IF     + +P L P+ +KDLG+  +++GLL+ +  L   +I    
Sbjct: 1   MNKQIFVLYFNIFLIF-LGIGLVIPVL-PVYLKDLGLTGSDLGLLVAAFALSQMIISPFG 58

Query: 61  GYIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISE 120
           G + DK+G+K ++ I ++ +S+S  +  +  ++  L+  R + G  AG+     T LI++
Sbjct: 59  GTLADKLGKKLIICIGLILFSVSEFMFAVGHNFSVLMLSRVIGGMSAGMVMPGVTGLIAD 118

Query: 121 LF-RERKGSALGF--------FMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIV 171
           +    +K    G+        F++GP IG       +  V+  + + +A   L I++ I+
Sbjct: 119 VSPSHQKAKNFGYMSAIINSGFILGPGIGG-----FMAEVSHRMPFYFAG-ALGILAFIM 172

Query: 172 GILLMVAIKG---------EPIKVEGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYL 222
            ++L+   K          EP  +  + +K+     +L+L    GL AF  + +   SY 
Sbjct: 173 SVVLIHDPKKSTTSGFQKLEPQLLTKINWKVFITPAILTLVLAFGLSAFETLYSLYTSYK 232

Query: 223 VSRGVGMEKASLMFSMLSLVGILGSIIAGFLYD----HLGKVSVLLAYALNSLLTFLVIV 278
           V+     +  S+    ++  GI G++   + +D    +  +++ +    + S++  +++V
Sbjct: 233 VN--YSPKDISI---AITGGGIFGALFQIYFFDKFMKYFSELTFIAWSLIYSVIVLVLLV 287

Query: 279 IPSPLFLIPLGLVLYSVGGIM-----TAYTSEKASRENLGVVMGFVNMVGFFGATIGPYI 333
           I    + I +   +  +G  M     T Y S  A  +  G   G  +     G  IGP I
Sbjct: 288 IADGYWTIMVISFVVFIGFDMIRPAITNYFSNIAG-DRQGFAGGLNSTFTSMGNFIGPLI 346

Query: 334 VGFLID 339
            G L D
Sbjct: 347 AGALFD 352


>emb|CAB76354.1| (AL158061) putative transmembrane transport protein. [Streptomyces
           coelicolor A3(2)]
           Length = 422
           
 Score = 76.9 bits (186), Expect = 4e-13
 Identities = 74/336 (22%), Positives = 158/336 (47%), Gaps = 26/336 (7%)

Query: 26  SLAPIIMKD--LGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSLS 83
           ++ P ++K   LG+   +   + T  L+  ++  V  G + D++GR++LL  S++ +S+ 
Sbjct: 42  AIIPTLLKTHHLGMTAGDATTIATLSLVGVAIGAVCVGPLADRLGRRRLLIGSVVLFSVL 101

Query: 84  SALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISE-LFRERKGSALGFFMVGPAIGSG 142
           + ++ L         +R L G   G     +  +++E +   R+  A    M G   G+ 
Sbjct: 102 TVVVPLANSVAMFAALRLLAGLGLGACMPVSLTMMAEHMPASRRARASTLTMTGYHTGAV 161

Query: 143 ITPLIVVPVALTLSWRYAFLVLSIMSSIVGIL----LMVAIKGEPIKVEGVKFKIP---- 194
           IT L+ + V  T +W   F +L ++  ++  +    L  +   E  + +G + ++P    
Sbjct: 162 ITSLLALQV--TDNWEILFYLLGVVGLVIAAIQWFKLPESAAFERARRDGAQ-RVPFTEL 218

Query: 195 ------RGVFLLSLANFLGLGAFFAMLTFLVSYLVSRGVGMEKASLMFSMLSLVGILGSI 248
                 R    + +A+F+GL   + + T+L   +   G  +  A     +L++ G++G +
Sbjct: 219 LKPAYLRAGIGIWVASFMGLLLVYGLNTWLPKLMNDAGYPVPTAVTQLLVLNIGGVVGLV 278

Query: 249 IAGFLYDHLG-KVSVLLAYALNSL-LTFLVIVIPSPLFLIPL----GLVLYSVGGIMTAY 302
           + G++ D  G K + ++ +A++ L L  L + + S L L  +    G+ ++S   ++ AY
Sbjct: 279 LGGYVADRRGIKGTTMVWFAVSVLMLGCLSVKMASDLLLNVVVFFTGVFVFSAMVLVYAY 338

Query: 303 TSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLI 338
            +        G  +G  + +G  G+ +GP I G L+
Sbjct: 339 VTHFYPASVRGTALGSASGIGRIGSIVGPSITGALV 374


>gb|AAK42961.1| Proline/betaine transporter, putative [Sulfolobus solfataricus]
           Length = 446
           
 Score = 76.5 bits (185), Expect = 5e-13
 Identities = 98/414 (23%), Positives = 182/414 (43%), Gaps = 69/414 (16%)

Query: 12  LGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPA-------GYIG 64
           +G++ +      + S+AP++ K + +  A   +   +++L YSL  +         G +G
Sbjct: 19  IGFLLDSYDLTMILSIAPVLAKVI-LPPASPLIATFNIILSYSLTIIFRPLGSAIFGNLG 77

Query: 65  DKIGRKKLLTISILGYSLSSALIVLTRDYWD--------LVTVRALYGFFAGLYYAPATA 116
           DKIGR+  L I++LG  ++SAL      Y           V +R   G FAG  Y+    
Sbjct: 78  DKIGRRADLIITVLGLGITSALTSALPTYAQAGILSFVLFVLIRVAVGIFAGGEYSAGHP 137

Query: 117 LISELFRER-----KGSALGFFMVGPAIGSGITPLIV----VPVALTLSWRYAFLVLSIM 167
              E    +      G   G F  G A+ + I  + +    V      +WRY FL  +++
Sbjct: 138 FAMEWTPYKWRGFISGLVQGGFSFGAALAAVIEGIFIGIYGVSGVEEFAWRYVFLT-AVI 196

Query: 168 SSIVGILLMVAIKGEPIKVEGVK-------------FKIP-RGVFLLSLANFLGLGAF-F 212
            + + + + +A+K  P+  E VK             FK P R  FL  +A   G+  F +
Sbjct: 197 PAFIALAVRLAMKETPV-FEDVKKKNLIRRTPLADLFKAPYRRDFLQVMAYMTGMFFFAY 255

Query: 213 AMLTFLVSYL--VSRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNS 270
           A+  F+ + L        + +A+ ++S+ +     G++I G L  ++G+  + + +   S
Sbjct: 256 ALFAFVPTILEHSPSTFSLGEANYIYSIGTYAAFAGALIFGTLSQYVGRRRLTIIW---S 312

Query: 271 LLTFLVIV---------------IPSPLFLIPLGLVLYSVGGIMTAYTSE--KASRENLG 313
           ++TF++ +               I + LF I +G++     GI+  Y SE  KAS    G
Sbjct: 313 IITFVIAIPIYYGLITAAIAGNAITAMLFSIIIGIITQGPWGIIPIYLSERFKASMRASG 372

Query: 314 VVMGF---VNMVGFFGATIGPYIVGFLIDRLGY-SLALLSVPLAYLVSAVIIGL 363
           V  G+   + + G+F   + P +  +L   L   +    S  +  ++ A+I+G+
Sbjct: 373 VGFGYSSGIFLGGWFSIYV-PLMHNYLFKSLDTPNNVWFSTAVLLMIGALIVGI 425


>gi|11498744 multidrug resistance protein [Archaeoglobus fulgidus]
           >gi|7483888|pir||G69392 multidrug resistance protein
           homolog - Archaeoglobus fulgidus
           >gi|2649446|gb|AAB90102.1| (AE001025) multidrug
           resistance protein [Archaeoglobus fulgidus]
           Length = 451
           
 Score = 76.5 bits (185), Expect = 5e-13
 Identities = 82/344 (23%), Positives = 140/344 (39%), Gaps = 31/344 (9%)

Query: 29  PIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSLSSALIV 88
           P I K+  I+   +G + T+ LL   +  VP G I D  GRKK+  + +L +SL S L  
Sbjct: 30  PAIGKEFQIDAITLGWIATAYLLAAGMFSVPFGRIADIAGRKKVFVVGLLVFSLGSILSA 89

Query: 89  LTRDYWDLVTVRALYGFFAGLYYAPATALISELF-RERKGSALGFFMVGPAIGSGITPLI 147
           +  +   L+  R L G    + +A + A+++ +F  + +G A+G        G  + P+ 
Sbjct: 90  IPPNAEMLIAFRVLQGVGGAMIFATSVAILTSVFPPQERGKAIGINTGAVYTGLSLGPIG 149

Query: 148 VVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKGEPIKVEGVKFKIPRGVFLLSLANFLG 207
              +   L WR  F+    +     I+  V ++GE     G KF +       ++  FL 
Sbjct: 150 GGFLTQNLGWRSLFIANGALGFFALIVASVYLRGEWADARGEKFDLAGSAIYAAMLFFLI 209

Query: 208 LG------AFFAMLTFLVSYLVSR---------GVGMEKASLMFSMLSLVGIL---GSII 249
            G      AF  +   L    V            V +  ++L FS+ SL  +L    +  
Sbjct: 210 YGFSEFSVAFIVLGAILALIFVVYENRQEHPVFAVRLLLSNLTFSLSSLAALLNYAATFA 269

Query: 250 AGFLYDHLGKVSVLLAYALN-SLLTFLVIVIPSPLFLIPLGLVLYSVGGIMTAYTSEKAS 308
            GFL      +S+ L Y       T  +I++  P   + + +     G I         +
Sbjct: 270 VGFL------MSLYLQYVKGFDAQTAGLILVSQP---VVMAIFAPIAGWISDRIEPRVVA 320

Query: 309 RENLGV-VMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVP 351
              + V  +  +   G  G T    I+ +L+  LG+ +AL S P
Sbjct: 321 STGMAVTTLSLILFAGINGETALSNIITYLM-LLGFGIALFSSP 363


>emb|CAA07482.1| (AJ007367) multi-drug resistance efflux pump [Streptococcus
           pneumoniae]
           Length = 399
           
 Score = 76.5 bits (185), Expect = 5e-13
 Identities = 91/384 (23%), Positives = 162/384 (41%), Gaps = 43/384 (11%)

Query: 10  ISLGWIFNY----SHRMAVPSLAPIIMKDLGINNAEI----GLLMTSLLLPYSLIQVPAG 61
           + + W  N+    S  + VP + PI +++LG+ + ++    GL ++   +  +L     G
Sbjct: 10  LRIAWFGNFLTGASISLVVPFM-PIFVENLGVGSQQVAFYAGLAISVSAISAALFSPIWG 68

Query: 62  YIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALI-SE 120
            + DK GRK ++  + L  +++   +    + + L+ +R L G FAG +   ATALI S+
Sbjct: 69  ILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYWLIFLRLLNGVFAG-FVPNATALIASQ 127

Query: 121 LFRERKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIK 180
           + +E+ GSALG    G   G+   P I   +A     R  FL++     +  IL +  IK
Sbjct: 128 VPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAELFGIRTVFLLVGSFLFLAAILTICFIK 187

Query: 181 GE----------PIKVEGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYLVSRG---- 226
            +          P K      K P  +  L L +F+   +  ++   L  Y+   G    
Sbjct: 188 EDFQPVAKEKAIPTKELFTSVKYPYLLLNLFLTSFVIQFSAQSIGPILALYVRDLGQTEN 247

Query: 227 ----VGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIV-IPS 281
                G+  +S+ FS +   G++G      L D +G   +L+     S++ +L+     S
Sbjct: 248 LLFVSGLIVSSMGFSSMMSAGVMGK-----LGDKVGNHRLLVVAQFYSVIIYLLCANASS 302

Query: 282 PL------FLIPLGLVLYSVGGIMTAYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVG 335
           PL      FL  LG      G  + A  S+   +  +  V  F  +  + G  +GP    
Sbjct: 303 PLQLGLYRFLFGLGTGALIPG--VNALLSKMTPKAGISRVFAFNQVFFYLGGVVGPMAGS 360

Query: 336 FLIDRLGYSLALLSVPLAYLVSAV 359
            +  + GY     +  L    S +
Sbjct: 361 AVAGQFGYHAVFYATSLCVAFSCL 384


>emb|CAB61680.1| (AL133213) putative transmembrane transport protein. [Streptomyces
           coelicolor A3(2)]
           Length = 440
           
 Score = 76.5 bits (185), Expect = 5e-13
 Identities = 88/361 (24%), Positives = 155/361 (42%), Gaps = 34/361 (9%)

Query: 36  GINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSLSSALIVLTRDYWD 95
           G+++ + GLL T  L+  ++    AG + D++GR + L ++++ Y++ +       +Y  
Sbjct: 72  GLDSGQTGLLTTVTLVVSAIGGALAGVLADRVGRVRALLLTVITYAVFTVACGFAPNYET 131

Query: 96  LVTVRALYGFFAGLYYAPATALISELFRE-RKGSALG----FFMVGPAIGSGITPLIVVP 150
           L+  RAL G   G  +A    L++E      +G  LG     + VG A+   +  L+   
Sbjct: 132 LLVFRALQGLGFGGEWAVGAILVAEYASPGHRGRTLGAIQSSWAVGWALAVVVYTLVFSL 191

Query: 151 VALTLSWRYAFLVLSIMSSIVGILLMVAIKGEPIKVEGVKFKIPRGVF------------ 198
               L+WR  F   ++ + +V + +  +++  P   E  +    RG F            
Sbjct: 192 AGDDLAWRVMFWTGALPALLV-VWVRRSVQDAPRAAEAREKGTGRGSFAAIFKPGTADSP 250

Query: 199 -LLSLANFLGL------GAFFAMLTFLVSYLV-SRGVGMEKASLMFSMLSLVGILGSIIA 250
            LL +  F  L      G ++ + T++ +YL   R + +       + L     LG +  
Sbjct: 251 GLLRVTLFASLLSTGVQGGYYTLATWVPTYLKDERDLSVVGTGGYLTFLISGAFLGYLTG 310

Query: 251 GFLYDHLGKVSVLLAYALNSLLTFLVIV-IP---SPLFLI---PLGLVLYSVGGIMTAYT 303
           G L D LG+   +  +AL S +  L    IP     L L+   PLG  + ++     +Y 
Sbjct: 311 GVLTDVLGRRRNIWLFALLSAVCILAYANIPRGADTLLLVLGFPLGFCMSAIFSGFGSYL 370

Query: 304 SEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAV-IIG 362
           SE       G   GF    G     + P  VGFL D  G   AL+   + Y ++A+ ++G
Sbjct: 371 SELYPTAVRGAGQGFTYNTGRAVGAVFPTTVGFLADSWGVGGALVFGAIGYGIAALALLG 430

Query: 363 L 363
           L
Sbjct: 431 L 431


>pir||F69814 fosmidmycin resistance protein homolog yfnC - Bacillus subtilis
           >gi|2116761|dbj|BAA20112.1| (D86418) YfnC [Bacillus
           subtilis] >gi|2633045|emb|CAB12551.1| (Z99107) similar
           to fosmidmycin resistance protein [Bacillus subtilis]
           >gi|2633056|emb|CAB12561.1| (Z99108) similar to
           fosmidmycin resistance protein [Bacillus subtilis]
           Length = 409
           
 Score = 76.1 bits (184), Expect = 6e-13
 Identities = 78/377 (20%), Positives = 157/377 (40%), Gaps = 45/377 (11%)

Query: 6   ILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGD 65
           ILI+I +  + N S +  +P++ PI+ + + +   ++G++  +L +  S++Q   G+  D
Sbjct: 22  ILIIIGICHMLNDSLQAVIPAMFPILERSMSLTFTQLGIIAFTLNMVSSVMQPVVGWYTD 81

Query: 66  KIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRER 125
           K  R   L + +    L    +     +  ++      G  + +++   + +       +
Sbjct: 82  KRPRPYALPVGLTASMLGILGLAFAPSFITILCCVFFIGLGSAIFHPEGSRVAYMAAGTK 141

Query: 126 KGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIK----- 180
           +G A   + VG   G  + PLI   + + L  ++  +  ++++++  + LM   K     
Sbjct: 142 RGLAQSIYQVGGNSGQAMAPLITALILVPLG-QFGAVWFTLVAALAVMFLMYIAKWYASR 200

Query: 181 -GEPIKVEGVKFKIPRG--------------VFLL--------SLANFLGLGAFFAMLTF 217
            G   +  G + K                  +FL+        ++ NF     F+AM T+
Sbjct: 201 LGSLAQKSGKQKKTAENTAITKSVVSALIIIIFLIFARSWYTSAIGNFY---TFYAMDTY 257

Query: 218 LVSYLVSRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVI 277
            VS        +++A     +  L G +G+ + G L D  GK  V+L   L S    +V+
Sbjct: 258 HVS--------IQQAQSYIFVFLLFGAIGTFLGGPLADRFGKRFVILGSLLCSAPLAIVL 309

Query: 278 VIPSPLF----LIPLGLVLYSVGGIMTAYTSEKASRENLGVVMGFVNMVGFFGATIGPYI 333
               P+     L  +GLVL S   +   Y  E    + +G + G    + F    IG   
Sbjct: 310 PFAGPVLAYGVLALIGLVLMSSFSVTVVYAQELVPGK-IGTMSGLTVGLAFGMGAIGAVA 368

Query: 334 VGFLIDRLGYSLALLSV 350
           +G LID  G +  ++++
Sbjct: 369 LGALIDAAGLTPTMIAI 385


>gb|AAB31949.1| (S74031) NorA {ISP794, quinolone resistance} [Staphylococcus
           aureus, NCTC 8325, Peptide Insertion, 388 aa]
           Length = 388
           
 Score = 76.1 bits (184), Expect = 6e-13
 Identities = 86/366 (23%), Positives = 163/366 (44%), Gaps = 41/366 (11%)

Query: 1   MEKLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPA 60
           M K I ++  ++  IF     + +P L P+ +KDLG+  +++GLL+ +  L   +I    
Sbjct: 1   MNKQIFVLYFNIFLIF-LGIGLVIPVL-PVYLKDLGLTGSDLGLLVAAFALSQMIISPFG 58

Query: 61  GYIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISE 120
           G + DK+G+K ++ I ++ +S+S  +  +  ++  L+  R + G  AG+     T LI++
Sbjct: 59  GTLADKLGKKLIICIGLILFSVSEFMFAVGHNFSVLMLSRVIGGMSAGMVMPGVTGLIAD 118

Query: 121 LF-RERKGSALGF--------FMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIV 171
           +    +K    G+        F++GP IG       +  V+  + + +A   L I++ I+
Sbjct: 119 ISPSHQKAKNFGYMSAIINSGFILGPGIGG-----FMAEVSHRMPFYFAG-ALGILAFIM 172

Query: 172 GILLMVAIKG---------EPIKVEGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYL 222
            I+L+   K          EP  +  + +K+     +L+L    GL AF      L S  
Sbjct: 173 SIVLIHDPKKSTTSGFQKLEPQLLTKINWKVFITPVILTLVLSFGLSAF----ETLYSLY 228

Query: 223 VSRGVGMEKASLMFSMLSLVGILGSIIAGFLYD----HLGKVSVLLAYALNSLLTFLVIV 278
            +  V      +  ++    GI G++   + +D    +  +++ +    L S++  +++V
Sbjct: 229 TADKVNYSPKDISIAITG-GGIFGALFQIYFFDKFMKYFSELTFIAWSLLYSVVVLILLV 287

Query: 279 IPSPLFLIPLGLVLYSVGGIM-----TAYTSEKASRENLGVVMGFVNMVGFFGATIGPYI 333
             +  + I L   +  +G  M     T Y S  A  E  G   G  +     G  IGP I
Sbjct: 288 FANDYWSIMLISFVVFIGFDMIRPAITNYFSNIAG-ERQGFAGGLNSTFTSMGNFIGPLI 346

Query: 334 VGFLID 339
            G L D
Sbjct: 347 AGALFD 352


>sp|P21191|NORA_STAAU QUINOLONE RESISTANCE NORA PROTEIN >gi|97835|pir||A37838 norA
           protein - Staphylococcus aureus
           >gi|216975|dbj|BAA14147.1| (D90119) ORF for norA
           [Staphylococcus aureus]
           Length = 388
           
 Score = 75.7 bits (183), Expect = 8e-13
 Identities = 86/366 (23%), Positives = 163/366 (44%), Gaps = 41/366 (11%)

Query: 1   MEKLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPA 60
           M K I ++  ++  IF     + +P L P+ +KDLG+  +++GLL+ +  L   +I    
Sbjct: 1   MNKQIFVLYFNIFLIF-LGIGLVIPVL-PVYLKDLGLTGSDLGLLVAAFALSQMIISPFG 58

Query: 61  GYIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISE 120
           G + DK+G+K ++ I ++ +S+S  +  +  ++  L+  R + G  AG+     T LI++
Sbjct: 59  GTLADKLGKKLIICIGLILFSVSEFMFAVGHNFSVLMLSRVIGGMSAGMVMPGVTGLIAD 118

Query: 121 LF-RERKGSALGF--------FMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIV 171
           +    +K    G+        F++GP IG       +  V+  + + +A   L I++ I+
Sbjct: 119 ISPSHQKAKNFGYMSAIINSGFILGPGIGG-----FMAEVSHRMPFYFAG-ALGILAFIM 172

Query: 172 GILLMVAIKG---------EPIKVEGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYL 222
            I+L+   K          EP  +  + +K+     +L+L    GL AF      L S  
Sbjct: 173 SIVLIHDPKKSTTSGFQKLEPQLLTKINWKVFITPVILTLVLSFGLSAF----ETLYSLY 228

Query: 223 VSRGVGMEKASLMFSMLSLVGILGSIIAGFLYD----HLGKVSVLLAYALNSLLTFLVIV 278
            +  V      +  ++    GI G++   + +D    +  +++ +    L S++  +++V
Sbjct: 229 TADKVNYSPKDISIAITG-GGIFGALFQIYFFDKFMKYFSELTFIAWSLLYSVVVLILLV 287

Query: 279 IPSPLFLIPLGLVLYSVGGIM-----TAYTSEKASRENLGVVMGFVNMVGFFGATIGPYI 333
             +  + I L   +  +G  M     T Y S  A  E  G   G  +     G  IGP I
Sbjct: 288 FANGYWSIMLISFVVFIGFDMIRPAITNYFSNIAG-ERQGFAGGLNSTFTSMGNFIGPLI 346

Query: 334 VGFLID 339
            G L D
Sbjct: 347 AGALFD 352


>pir||D83117 probable MFS transporter PA4233 [imported] - Pseudomonas aeruginosa
           (strain PAO1) >gi|9950449|gb|AAG07621.1|AE004840_7
           (AE004840) probable MFS transporter [Pseudomonas
           aeruginosa]
           Length = 462
           
 Score = 75.7 bits (183), Expect = 8e-13
 Identities = 83/358 (23%), Positives = 155/358 (43%), Gaps = 45/358 (12%)

Query: 22  MAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYS 81
           M +P LA       G   A IGL + +  L  +++Q+P G I D+IGR+ ++ + +L ++
Sbjct: 33  MVLPVLATYGQDLAGATPALIGLAIGAYGLTQAILQIPFGTISDRIGRRPVIVVGLLIFA 92

Query: 82  LSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRERKGSALGFFMVGPAIG- 140
             +AL       W ++  R L G  AG   A   AL+S+L RE+  +     M+G +IG 
Sbjct: 93  AGAALAANADSIWGVIAGRVLQG--AGAISAAVMALLSDLTREQHRTK-AMAMIGMSIGV 149

Query: 141 SGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKGEPIKV-------------- 186
           S    +++ PV   L   +     +   ++VG+LL++    +P  +              
Sbjct: 150 SFAVAMVLGPVLTHLFGLHGLFWFTAGMALVGLLLILFFVPQPDHMTQHRESSVARQALL 209

Query: 187 ----EGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYLVSRGVGMEKASLMFSMLSLV 242
                G   ++  G+ +L   + + + +F A+   LV      G+  E+   ++    LV
Sbjct: 210 PTLKHGDLLRLDAGILIL---HAILMASFVALPLALVH---EGGLPKEQHWWVYLTALLV 263

Query: 243 GILGSIIAGFLYDHLGKVSVLLAYALNSLLT--FLVIVIPSPLFLIPLGLVLYSVGGIMT 300
           G  G +      +   ++  +L  A+ +LL      +V    L ++ +G V++      T
Sbjct: 264 GFFGMVPFIIYAEKKRRMKRVLTGAVATLLACELFFLVFGHSLAMLVVGTVVF-----FT 318

Query: 301 AYTSEKASRENL----------GVVMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALL 348
           A+   +AS  +L          G  MG  +   F GA +G  + G++    G S+  +
Sbjct: 319 AFNLLEASLPSLVSKVSPAGGKGTAMGVYSTSQFLGAALGGILGGWMFQHGGLSMVFI 376


>pir||B82991 glycerol-3-phosphate transporter PA5235 [imported] - Pseudomonas
           aeruginosa (strain PAO1)
           >gi|9951544|gb|AAG08620.1|AE004936_3 (AE004936)
           glycerol-3-phosphate transporter [Pseudomonas
           aeruginosa]
           Length = 448
           
 Score = 75.7 bits (183), Expect = 8e-13
 Identities = 83/407 (20%), Positives = 174/407 (42%), Gaps = 52/407 (12%)

Query: 10  ISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGR 69
           I +G+   Y  R       P +++D G +  ++G+ M+++ + Y L +   G + D+   
Sbjct: 34  IFIGYAGYYLLRKNFSLAMPYLIED-GYSRGQLGVAMSAIAIAYGLSKFIMGLVSDRSNP 92

Query: 70  KKLLTISILGYSLSSALIVLTRDYWDLVTVRALY------GFFAGLYYAPA-TALISELF 122
           +  L   +L    ++ + +    +W   +V  ++      G+  G+ + P+   ++    
Sbjct: 93  RVFLPFGLL--VSAAVMFIFGFAHWATSSVAIMFVLLFINGWAQGMGWPPSGRTMVHWWS 150

Query: 123 RERKGSALGFFMVGPAIGSG-ITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKG 181
           ++ +GS +  + V   +G G I PL ++ +AL   WR AF V +I++  V +    A++ 
Sbjct: 151 QKERGSVVSVWNVAHNVGGGLIGPLFLLGLALFGDWRSAFYVPAIVAVGVAVFAYFAMRD 210

Query: 182 EPIK-----VEGVKFKIPRG------------------------VFLLSLANFLGLGAFF 212
            P       +E  K   P G                        ++ ++LAN       +
Sbjct: 211 TPQSCGLPPIEKHKDDYPEGYDEHHERELSTKEIFVTYVLRNKLLWYIALANVFVYLLRY 270

Query: 213 AMLTFLVSYL-VSRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVS------VLLA 265
            +L +  +YL  ++   ++K+S  +      GI G+++ G+L D L K +      V + 
Sbjct: 271 GVLDWAPTYLKEAKHFNVDKSSWAYFFYEWAGIPGTLLCGWLSDKLFKGNRGATGVVFMI 330

Query: 266 YALNSLLTFLVIVIPSPLF----LIPLGLVLYSVGGIMTAYTSEKASRENLGVVMGFVNM 321
                 L + +    +P      LI +G ++Y    ++     E A ++  G   GF  +
Sbjct: 331 LVTVGTLIYWLNPAGNPAIDMAALIMIGFLIYGPVMLIGLQALELAPKKAAGTAAGFTGL 390

Query: 322 VGFFGATIGP-YIVGFLIDRLGYSLALLSVPLAYLVSAVIIGLDLRK 367
            G+ G ++    +VG+ +D  G+      +  A L++ + + L LRK
Sbjct: 391 FGYLGGSVAANALVGYTVDHFGWDGGFKLLIGACLLAILFLCLTLRK 437


>sp|P42237|GUDP_BACSU PROBABLE GLUCARATE TRANSPORTER (D-GLUCARATE PERMEASE)
           >gi|7428803|pir||H69752 probalble glucarate transporter
           - Bacillus subtilis >gi|709999|dbj|BAA06469.1| (D30808)
           glucarate dehydratase [Bacillus subtilis]
           >gi|2632534|emb|CAB12042.1| (Z99105) similar to
           glucarate transporter [Bacillus subtilis]
           Length = 455
           
 Score = 74.5 bits (180), Expect = 2e-12
 Identities = 87/408 (21%), Positives = 168/408 (40%), Gaps = 53/408 (12%)

Query: 6   ILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGD 65
           I+ ++ L    NY+ R  +      +  DLG+++  +G + ++    Y + Q+P G++ D
Sbjct: 21  IVFMLFLVTSINYADRATLSITGDSVQHDLGLDSVAMGYVFSAFGWAYVIGQLPGGWLLD 80

Query: 66  KIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYG--FFAGLYYAPA-----TALI 118
           + G K ++ +SI  +S  + L      +     +  L+   F  GL  AP+       + 
Sbjct: 81  RFGSKTIIALSIFFWSFFTLLQGAIGFFSAGTAIILLFALRFLVGLSEAPSFPGNGRVVA 140

Query: 119 SELFRERKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVA 178
           S      +G+A  FF         I P ++  +  +  W   F+V+ I   ++ ++ +  
Sbjct: 141 SWFPSSERGTASAFFNSAQYFAIVIFPPLMGWLTHSFGWHSVFVVMGIAGILLAVIWLKT 200

Query: 179 I---KGEPIKVEGVKFKIPRGVFLLS--------------------LANFLGLGAFFA-- 213
           +   K  P   E     I +G  L+S                    L N + +G + A  
Sbjct: 201 VYEPKKHPKVNEAELAYIEQGGGLISMDDSKSKQETESKWPYIKQLLTNRMLIGVYIAQY 260

Query: 214 --------MLTFLVSYLV-SRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLL 264
                    LT+   YLV +RG+ + +A  + S+ +L G  G ++ G + D L K    L
Sbjct: 261 CITTLTYFFLTWFPVYLVQARGMSILEAGFVASLPALCGFAGGVLGGIVSDILLKKGRSL 320

Query: 265 AYA------LNSLLTFLVIVI----PSPLFLIPLGLVLY--SVGGIMTAYTSEKASRENL 312
            +A         LL+  +IV      + L ++ + L  +    G +  A  S+ + +E  
Sbjct: 321 TFARKVPIIAGMLLSCSMIVCNYTDSAWLVVVIMSLAFFGKGFGALGWAVVSDTSPKECA 380

Query: 313 GVVMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVI 360
           G+  G  N  G   +   P I+G++++  G     L    A  ++A++
Sbjct: 381 GLSGGLFNTFGNIASITTPIIIGYIVNATGSFNGALVFVGANAIAAIL 428


>pir||F83233 probable MFS transporter PA3303 [imported] - Pseudomonas aeruginosa
           (strain PAO1) >gi|9949431|gb|AAG06691.1|AE004752_7
           (AE004752) probable MFS transporter [Pseudomonas
           aeruginosa]
           Length = 391
           
 Score = 74.5 bits (180), Expect = 2e-12
 Identities = 88/371 (23%), Positives = 168/371 (44%), Gaps = 17/371 (4%)

Query: 7   LILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDK 66
           L+L+SL           +  + P + +DL ++ +  G L T   L ++L     G++  +
Sbjct: 5   LLLLSLTTFAAGLAESILIGILPPLAEDLRVSISLAGQLTTLFSLGFALAAPLLGWLTRR 64

Query: 67  IGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRE-R 125
           I R++LL  ++L ++LS+AL  L   Y  L+  R       GL    A+ L +EL    +
Sbjct: 65  IERRRLLLATLLLFALSNALAALAPGYLGLLLARLGMSACCGLLIVLASLLAAELAAPAQ 124

Query: 126 KGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIK----G 181
           +G A+G   +G +        + V ++    WR+ F  +++ S  + +LL   +     G
Sbjct: 125 RGRAIGLIFMGISGSLVFGVPLGVQISDWFGWRWIFAGIAVYSLPLCLLLWRYLPQRQAG 184

Query: 182 EPIKVEGVKFKIPR-GVFLLSLANFLGLGAFFAMLTFLVSYLVSR-GV-GMEKASLMFSM 238
           +    EG   ++ +  ++L  L + L LG  F +  +   YL S  G+    + SL+  +
Sbjct: 185 DLPGREGYLRQLRQPALWLAQLVSILLLGGHFTLFAYFTPYLASMAGIRSPSEISLILLL 244

Query: 239 LSLVGILGSIIAGFLYDHLG-KVSVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSVGG 297
           + L  + G  I G+L DHLG + ++ L  A  +L    V +    +  +P+ +V  ++  
Sbjct: 245 IGLAALSGGYIGGWLADHLGHRRALRLVPAAFALALAAVPLSLGSIGFLPVLMVWSAISW 304

Query: 298 IMTAYTSEKASRE-----NLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPL 352
           +++        R      + GV +    M    G  +G  + G ++  LG + A   V L
Sbjct: 305 MISPVVQSFLLRSDPASGSAGVALNTSAM--HLGVGLGAALGGLVVAALGVA-ATPWVGL 361

Query: 353 AYLVSAVIIGL 363
           A +++A+   L
Sbjct: 362 ALVLAALACAL 372


>pir||H71846 hypothetical protein jhp1111 - Helicobacter pylori (strain J99)
           >gi|4155710|gb|AAD06692.1| (AE001539) putative
           [Helicobacter pylori J99]
           Length = 391
           
 Score = 74.1 bits (179), Expect = 2e-12
 Identities = 67/297 (22%), Positives = 135/297 (44%), Gaps = 22/297 (7%)

Query: 14  WIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLL 73
           +IFN +  + V  L+ I  K   + +A +GL++T+     SL  +P   +  KI RK+LL
Sbjct: 24  FIFNTTEFVPVALLSDIA-KSFEMESATVGLMITAYAWVVSLGSLPLMLLSAKIERKRLL 82

Query: 74  TISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELF-RERKGSALGF 132
                 +  S  L  L  ++W L+  R    F   ++++   +L+  +  R +K  ALG 
Sbjct: 83  LFLFALFIFSHILSALAWNFWVLLLSRMGIAFAHSIFWSITASLVIRVAPRNKKQQALGL 142

Query: 133 FMVGPAIGSGITPLIVVP----VALTLSWRYAFLVLSIMSSIVGILLMVAIKGEPIKVEG 188
                A+GS +  ++ +P    +   L WR  F V+  +++++ +L+   +   P +  G
Sbjct: 143 L----ALGSSLAMILGLPLGRIIGQILDWRSTFGVIGGVATLIMLLMWKLLPHLPSRNAG 198

Query: 189 VKFKIP--------RGVFLLSLANFLGLGAFFAMLTFLVSYLVS-RGVGMEKASLMFSML 239
               +P         G++LL +   + +   F   +++  +++       +  +LM  + 
Sbjct: 199 TLASVPILMKRPLLVGIYLLVI---MVISGHFTTYSYIEPFIIQISQFSPDITTLMLFVF 255

Query: 240 SLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSVG 296
            L G++GS + G LY    +  +  A  L      L+ V  +  ++I L + L+ +G
Sbjct: 256 GLAGVVGSFLFGRLYAKNSRKFIAFAMVLVICPQLLLFVFKNLEWVIFLQIFLWGIG 312


>gb|AAG23889.1| (AY008833) TcaB [Staphylococcus aureus]
           Length = 402
           
 Score = 74.1 bits (179), Expect = 2e-12
 Identities = 88/362 (24%), Positives = 162/362 (44%), Gaps = 41/362 (11%)

Query: 4   LIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYI 63
           + I+IL SL  I   S  M +P L P I  D     +   L ++  ++  +   + AG I
Sbjct: 13  IFIIILGSLTAIGALSIDMFLPGL-PDIRHDFQTTTSNAQLTLSMFMIGLAFGNLFAGPI 71

Query: 64  GDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFR 123
            D  GR+K L I+++ ++L+S  IV   + W +V +R L G   G     + A+ S+++ 
Sbjct: 72  SDSTGRRKPLIIAMIIFTLASLGIVFVHNIWLMVALRFLQGVTGGAAAVISRAIASDMY- 130

Query: 124 ERKGSALGFFMVGPAIGSGITPLI---VVPVALTLS-WRYAFLVLSIMS--SIVGILLMV 177
              G+ L  FM    + +GI P++   +  + L  S WR  F++L+I     ++G LL V
Sbjct: 131 --SGNELTKFMALLMLVNGIAPVVAPTIGGIILNYSVWRMVFVILTIFGFVMVIGSLLKV 188

Query: 178 AIKGEPIKV------EGVKFKIPRGVFLLSLANF----LGLGAFFAMLTFLVS---YLVS 224
               E + V       G+K        LL    F    L  G  F +L   +S   +++ 
Sbjct: 189 P---ESLTVTNRESSSGLKTMFKNFKILLKTPRFVLPMLIQGMTFVILFTYISASPFIIQ 245

Query: 225 RGVGME--KASLMFSMLSLVGILGSIIAGFLYDHLGKVSVL----LAYALNSLLTFLVIV 278
           +  GM   + S MF+ + +  I+ S + G+L D +    ++    +   +  +L  +V++
Sbjct: 246 KIYGMTAIQFSWMFAGIGITLIISSQLTGYLVDFIDSQKLMRGMTMIQIIGVILVTIVLL 305

Query: 279 IPSPLFLIPLGLVLY--SVGGIMT-----AYTSEKASRENLGVVMGFVNMVGFFGATIGP 331
                +++ +G ++    V G+ T     A     + R +   ++G V  +  FG    P
Sbjct: 306 NHWNFWILAIGFIILIAPVTGVATLGFTIAMDESSSGRGSSSSLLGLVQFL--FGGVASP 363

Query: 332 YI 333
            +
Sbjct: 364 LV 365


>gb|AAK42828.1| Permease [Sulfolobus solfataricus]
           Length = 419
           
 Score = 73.4 bits (177), Expect = 4e-12
 Identities = 91/410 (22%), Positives = 169/410 (41%), Gaps = 61/410 (14%)

Query: 5   IILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIG 64
           I+LI+ +L  I +Y  R  + +  P++  +  I++ E G++       Y ++    GY  
Sbjct: 9   IVLIIFAL-IIVDYIDRGLINTALPVLKSEFHISSFEAGIIGDGFTFGYLIMNPLVGYFL 67

Query: 65  DKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRE 124
           DK G K++ +   + +    A+ V     +  +  R L G    + +   T +++   R+
Sbjct: 68  DKYGPKRVFSRFAILWGAVQAINVFAFSTFYFIVTRVLLGIGEAVGFPGVTKIVANWLRK 127

Query: 125 RKGSALGFFMVGPAIGSGIT-------PLIVVPVALTLSWRYAFLVLSIMSSIVGIL--- 174
            +  A G  +    +  GI         L  +     L+WR  FLV  +++ I+ I+   
Sbjct: 128 DE-KARGGTISDSGVNLGIVFGSLFMLGLFAIIPNQELAWRLGFLVSGLLAIILAIILGR 186

Query: 175 LMVAIKGEPIKVE--------------GVKFKIPRGVFLLSLANFLG--------LGAFF 212
           L+  +  +  K+               GVK K+P   +L S  N+ G         G FF
Sbjct: 187 LLYDLPEQHPKISKEELDYILSGREKVGVKTKLPLSYWLRS-KNYWGYMQGLGAQAGIFF 245

Query: 213 AMLTFLVSYL-----VSRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYA 267
            + T+L  YL     +S    +E  +L++S     G +G ++ G++ D L K +  L + 
Sbjct: 246 GLFTWLPLYLFYARHLSLSFTLEYTALIWSF----GFIGELVGGYVVDKLIKRNPNLGFK 301

Query: 268 LNSLLTFLVI--------VIPSPLFLIPLGLVLYSV---GGIMTAYTSEKASRENLGVVM 316
           +   ++ L +        +I SP+  + + +V +      GI  A  S   S E  G   
Sbjct: 302 VGFAVSSLAVTIGLAAATLISSPIEAVEILMVTFFFLRWSGIQWAAPSFLVSTELAGQFG 361

Query: 317 GFVNMVGFFGATIGPYIVGFLID-----RLGYSLALLSVPLAYLVSAVII 361
           G +         I P + G  ++      LG  + L+ + L Y +  VII
Sbjct: 362 GHIGFWETLWGIIVPIVFGATVEVTKAYLLGMEI-LIGIGLIYFIGTVII 410


>sp|O34691|YCEI_BACSU HYPOTHETICAL METABOLITE TRANSPORT PROTEIN IN RAPJ-OPUAA INTERGENIC
           REGION >gi|7475934|pir||C69757 transporter homolog yceI
           - Bacillus subtilis >gi|2415746|dbj|BAA22256.1|
           (AB000617) YceI [Bacillus subtilis]
           >gi|2632581|emb|CAB12089.1| (Z99105) similar to
           transporter [Bacillus subtilis]
           Length = 400
           
 Score = 73.4 bits (177), Expect = 4e-12
 Identities = 91/398 (22%), Positives = 176/398 (43%), Gaps = 47/398 (11%)

Query: 6   ILILISLGWIFN------YSHRMAVP----SLAPIIMKDLGINNAEIGLLMTSLLLPYSL 55
           +L +  LGW+F+       S  +A      +L+P  MK +G  N+ IG+   + L     
Sbjct: 12  LLGVAGLGWLFDAMDVGILSFIIAALHVEWNLSPEEMKWIGSVNS-IGMAAGAFLF---- 66

Query: 56  IQVPAGYIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPAT 115
                G + D+IGRKK+  I++L +S+ S +          + +R + G   G     A+
Sbjct: 67  -----GLLADRIGRKKVFIITLLCFSIGSGISAFVTSLSAFLILRFVIGMGLGGELPVAS 121

Query: 116 ALISE-LFRERKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGIL 174
            L+SE +  E++G  +       A+G     LI   V  +  W+ A L+L+ +++   + 
Sbjct: 122 TLVSEAVVPEKRGRVIVLLESFWAVGWLAAALISYFVIPSFGWQ-AALLLTALTAFYALY 180

Query: 175 LMVAIKGEPIKVEGVKFK---------------IPRGVFLLSLANFLGLGAFFAMLTFLV 219
           L  ++   P K E +  K                 R   +LS+  F  + +++ M  +L 
Sbjct: 181 LRTSLPDSP-KYESLSAKKRSMWENVKSVWARQYIRPTVMLSIVWFCVVFSYYGMFLWLP 239

Query: 220 SYLVSRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSL-LTFLVIV 278
           S ++ +G  M ++     +++L  + G   A +L +  G+  +L+ Y + +    +    
Sbjct: 240 SVMLLKGFSMIQSFEYVLLMTLAQLPGYFSAAWLIEKAGRKWILVVYLIGTAGSAYFFGT 299

Query: 279 IPSPLFLIPLGLVL--YSVG--GIMTAYTSEKASRENLGVVMGFVNMVGFFGATIGPYIV 334
             S   L+  G++L  +++G  G++ AYT E+          G     G  G   GP +V
Sbjct: 300 ADSLSLLLTAGVLLSFFNLGAWGVLYAYTPEQYPTAIRATGSGTTAAFGRIGGIFGPLLV 359

Query: 335 GFLIDR-LGYSLALLSVPLAYLVSA---VIIGLDLRKT 368
           G L  R + +S+      +A L++    +I+G + ++T
Sbjct: 360 GTLAARHISFSVIFSIFCIAILLAVACILIMGKETKQT 397


>sp|Q43975|PCAK_ACICA 4-HYDROXYBENZOATE TRANSPORTER >gi|3172116|gb|AAC37151.1| (L05770)
           putative transport protein [Acinetobacter sp. ADP1]
           Length = 457
           
 Score = 73.4 bits (177), Expect = 4e-12
 Identities = 84/395 (21%), Positives = 164/395 (41%), Gaps = 57/395 (14%)

Query: 23  AVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSL 82
           A+  +AP + +D G++ +++G +M++ L    +  + +G   D+ GRK +L++S+L +  
Sbjct: 54  AMGFIAPALAQDWGVDRSQLGPVMSAALGGMIIGALVSGPTADRFGRKIVLSMSMLVFGG 113

Query: 83  SSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRERKGSALGFFM-----VGP 137
            +     + +   LV  R L G   G     AT L SE    R  S L   M     +G 
Sbjct: 114 FTLACAYSTNLDSLVIFRFLTGIGLGAAMPNATTLFSEYCPARIRSLLVTCMFCGYNLGM 173

Query: 138 AIGSGITPLIVVPVA-----LTLSWRYAFLVLSIMSSIVGILLMVAIKGE---------- 182
           AIG  I+  ++         L   W    L+L ++  +      + +KG+          
Sbjct: 174 AIGGFISSWLIPAFGWHSLFLLGGWAPLILMLLVIFFLPESYRFLIVKGKNTKKVRQILS 233

Query: 183 ---PIKVEGV-KFKIP----------------------RGVFLLSLANFLGLGAFFAMLT 216
              P KV+GV +F +P                      +G  LL +  F+GL   + + +
Sbjct: 234 RIAPQKVQGVTEFHVPEEKVEAGTKKGVFGMLFSAKYVKGTVLLWVTYFMGLVMIYLLTS 293

Query: 217 FLVSYLVSRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLV 276
           +L + +   G  +E+A+ +  +    G+L ++  G+  D      ++  + L + + F V
Sbjct: 294 WLPTLMRETGASLERAAFLGGLFQFGGVLSALFIGWAMDRFNPNRIIAGFYLAAGI-FAV 352

Query: 277 IVIPS-------PLFLIPLGLVLYSVGGIMTAYTSEKASRENLGVVMGFVNMVGFFGATI 329
           IV  S        LF++  G+ +      M   ++     +     + +++ +G FGA  
Sbjct: 353 IVGQSLSNPTLLALFILCAGIAVNGAQSSMPVLSARFYPTQCRATGVAWMSGIGRFGAVF 412

Query: 330 GPYIVGFLIDR---LGYSLALLSVPLAYLVSAVII 361
           G +I   L+         L++L +P      A+ +
Sbjct: 413 GAWIGAVLLGNNWSFTMILSMLIIPARAAAIAIFV 447


>pir||S56583 hypothetical protein f261b - Escherichia coli
           >gi|537199|gb|AAA97254.1| (U14003) ORF_f261b
           [Escherichia coli]
           Length = 261
           
 Score = 73.0 bits (176), Expect = 5e-12
 Identities = 41/168 (24%), Positives = 82/168 (48%), Gaps = 1/168 (0%)

Query: 7   LILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDK 66
           ++L+    + NY  R ++      I ++LG++  EIG L++   L Y + Q+P G + D+
Sbjct: 44  MLLLFFAAVINYLDRSSLSVANLTIREELGLSATEIGALLSVFSLAYGIAQLPCGPLLDR 103

Query: 67  IGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFR-ER 125
            G + +L + +  +SL  A+  +  ++   V VR   G            +I++ F  + 
Sbjct: 104 KGPRLMLGLGMFFWSLFQAMSGMVHNFTQFVLVRIGMGIGEAPMNPCGVKVINDWFNIKE 163

Query: 126 KGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGI 173
           +G  +GFF     IG  ++P I+  + L + WR  F+ + ++   + I
Sbjct: 164 RGRPMGFFNAASTIGVAVSPPILAAMMLVMGWRGMFITIGVLGIFLAI 211


>pir||E69783 bicyclomycin resistance protein homolog ydgK - Bacillus subtilis
           >gi|1881374|dbj|BAA19401.1| (AB001488) SIMILAR TO
           BICYCLOMYCIN RESISTANCE PROTEIN. [Bacillus subtilis]
           >gi|2632881|emb|CAB12387.1| (Z99107) similar to
           bicyclomycin resistance protein [Bacillus subtilis]
           Length = 402
           
 Score = 73.0 bits (176), Expect = 5e-12
 Identities = 88/366 (24%), Positives = 160/366 (43%), Gaps = 37/366 (10%)

Query: 22  MAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYS 81
           M +PS  P I KDL  + + + L +T+ L+  ++ Q+  G + D  GR+K L I I  ++
Sbjct: 30  MYLPSF-PEIAKDLSASASLVQLSLTACLVGLTIGQLIVGPVSDAQGRRKPLLICIFLFA 88

Query: 82  LSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRERKGSA-LGFFMVGPAIG 140
           LSS    L+ +   LV  R L GF A      + A++ ++F  R+ S      MV  A+ 
Sbjct: 89  LSSLFCALSPNITTLVAARFLQGFTASAGLVLSRAIVRDVFTGRELSKFFSLLMVITAVA 148

Query: 141 SGITP-----LIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIK-------------GE 182
             + P     ++++P A   +W   F VL I+  ++ +L+ + +K             G 
Sbjct: 149 PMVAPMTGGAILLLPFA---TWHTIFHVLMIIGFLLVLLIALRLKETLPLEKRIPSSIGT 205

Query: 183 PIKVEGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYLVSRGVGMEKASLMFSMLSLV 242
            +K  G   K    +       F+  G+F  +      Y    GV  +  S++F +  L 
Sbjct: 206 SVKTMGSLLKDRSFMGYALTVGFIHGGSFAYVSGTPFVYQDIYGVSPQVFSILFGINGLA 265

Query: 243 GILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVI----VIPSPLFLIPLGLVLYSVGGI 298
            I GS I G     + + S+L    + +++   V+    +I  PL  + + + +Y +   
Sbjct: 266 IISGSFIIGRFGGIIHEKSLLRIAVITAMIATAVLLTMTMIHGPLATLVISIFIYMITIG 325

Query: 299 MTAYTSEKASRENLGVVMGFVNMVGFFGATIG--PYIVGFLIDRLGYSLALLSVPLAYL- 355
           M   ++   + E  G      +  G   A +G  P ++G ++  L       +VP+  + 
Sbjct: 326 MVLTSTFTLAMEKQG------HRAGSASALLGMLPLLLGSIVSPLVGINETTAVPMGAIM 379

Query: 356 -VSAVI 360
            V+AVI
Sbjct: 380 FVTAVI 385


>dbj|BAB04893.1| (AP001511) multidrug-efflux transporter [Bacillus halodurans]
           Length = 399
           
 Score = 73.0 bits (176), Expect = 5e-12
 Identities = 78/369 (21%), Positives = 158/369 (42%), Gaps = 48/369 (13%)

Query: 3   KLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGY 62
           K ++++++++ ++      + +P L P  ++  G ++ E+GLL+        L+    G 
Sbjct: 7   KPLLMLMVNM-FVVMMGIGLVIPIL-PYYIEAFGASSVELGLLIAIFSFMQFLLAPFWGR 64

Query: 63  IGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISE-L 121
           + DK+GRK L+ + + G++++  +      +W L   R L G F       A A +S+  
Sbjct: 65  LSDKVGRKPLIAVGMFGFAVAEFIFAFATQFWMLFVSRILAGAFGSAVMPAAMAYVSDRT 124

Query: 122 FRERKGSALGF--------FMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGI 173
             E++G  +G          +VGP IG  +    +    L   +  +F   + + S++ +
Sbjct: 125 SEEKRGHGMGLLGASMALGIVVGPGIGGWLAEFSLATPFLFAGFAASF---AAIFSLLWL 181

Query: 174 LLMVAIKGEPIKVEGVK--------FKIPRGVFL-------LSLANFLGLGAFFAMLTFL 218
              + ++    +VE V          + P G  L         LANF  +   FA+  F 
Sbjct: 182 PESLPLEKRKTEVEPVNQFVQMWQAVRSPIGFLLFLVFGLSFGLANFQTIFGIFALHRFH 241

Query: 219 VSYLVSRGVGMEKASLMFSMLSLVGILGSI----IAGFLYDHLGKVSVLLAYALNSLLTF 274
            +            S +  ++ L GI+G+I    + G L +  G+  V+L     S + F
Sbjct: 242 YN-----------PSEVGFIMVLTGIVGAIAQGSLVGRLTERYGEEKVVLGSLSLSGIGF 290

Query: 275 LVIVIPSPLFLIPLGLVLYSVGG--IMTAYTS--EKASRENLGVVMGFVNMVGFFGATIG 330
           L++++    + +     L+ +G   +  A  S   K + +  G++MG  N +   G  +G
Sbjct: 291 LIMMLAFNYWTVIATTCLFFLGNSILRPAVQSFLSKMAGDQQGMIMGLNNSILSLGNVVG 350

Query: 331 PYIVGFLID 339
             + G L +
Sbjct: 351 ALLAGLLFE 359


>gb|AAK41760.1| Transport protein [Sulfolobus solfataricus]
           Length = 430
           
 Score = 72.6 bits (175), Expect = 7e-12
 Identities = 102/415 (24%), Positives = 175/415 (41%), Gaps = 63/415 (15%)

Query: 12  LGWIFNYSHRMAVPSLAPIIMK-----DLGINNAEIGLLMTSLLLPYSLIQVPAG----- 61
           LGW+ +    +A   +A  I K      +GI    +GL+ T        +  P G     
Sbjct: 18  LGWLMDGYTSIAYALVAVTISKIFFPSTIGI----LGLIATFGGFAVGALARPVGSLVFG 73

Query: 62  -YIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALY--------GFFAGLYYA 112
            +IGDKIGRK +L ++ILG+SL ++   L   Y     +  L+        G FAG  Y 
Sbjct: 74  NFIGDKIGRKNMLVLTILGFSLIASSKALLPSYETAGILAPLFLYIILFAEGMFAGAEYG 133

Query: 113 PATALISELFRERKGSALGFFMVGPAIGSGITPLIVVPVAL----------TLSWRYAFL 162
             T L  E     K   +G F V    G+G   + +V  AL          TL WR  F 
Sbjct: 134 GGTTLALESVPVGKRGFIGSF-VQSGFGTGYFVISLVYSALYSMFGNEGFQTLGWRVLF- 191

Query: 163 VLSIMSSIVGILLMVAIKGEPI----KVEGVKFKIP-RGVFLLSLANFL-GL----GAFF 212
              I+  ++ +++       PI    K      KIP + +F +S ++ L GL    G  +
Sbjct: 192 ATCILPGLITLIIRKMTDESPIFKDMKSGNEVVKIPIKELFKMSYSSVLIGLMITSGLLY 251

Query: 213 ---AMLTFLVSYLVSRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHL--GKVSVLLAYA 267
              A  +F  + L  +G+      L  ++++LV + G    GFL D +  G+   +L Y+
Sbjct: 252 INTATFSFYPTVLTIQGIPGTIVGLSVAIINLVSLFGVWFGGFLADVIKRGRKVPMLIYS 311

Query: 268 LNSLLTFLVIVIPSPLFLIPLGLVLYS--------VGGIMTAYTSEKASRENLGVVMGFV 319
           +  + T   ++    L  + L  +++S        +   + A+ +E+ S++     +GF 
Sbjct: 312 IIFIFTVYPVLYLGLLKNVYLSTIVFSLQAFLEAMIFSTLPAFLAEQFSKKYRTTGVGFT 371

Query: 320 NMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAV--IIGLDLRKTSYKG 372
              G  G   G + +   +    Y   L S  +  +++ +  I+G+ L K +Y G
Sbjct: 372 YNGGAIG---GGFAISATLALSTYLGLLYSWSINIIIAGIIMIMGIVLAKETYTG 423


>gb|AAC45758.1| (U40014) nitrate transporter [Staphylococcus carnosus]
           Length = 388
           
 Score = 72.6 bits (175), Expect = 7e-12
 Identities = 82/364 (22%), Positives = 164/364 (44%), Gaps = 45/364 (12%)

Query: 24  VPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSLS 83
           +  L P+I +D+ I +++I +++   ++  S++++P GY+ + IG K +   S +   L 
Sbjct: 27  IAPLMPMISQDIKITSSQISIVLAIPVILGSVLRIPFGYLTNIIGAKWVFFSSFI--ILL 84

Query: 84  SALIVLTRDYWDLVTVRALYGFFAG----LYYAPATALISELFRERKGSALGFFMVGPAI 139
             + +L++     V +  L GFF G    ++    T++     +++ G A G + +G  +
Sbjct: 85  FPIFLLSQA--QSVNMLMLAGFFLGVGGAVFSVGVTSIPKYFPKDKVGLANGIYGMG-NL 141

Query: 140 GSGITPLIVVPVALTLSWRYAF-LVLSIMSSIVGILLMVAIKGEPIKVEGVKFKIP---- 194
           G+ ++  +  P+A  + W+    L L +M+    ++  +    EP      K KIP    
Sbjct: 142 GTAVSSFLAPPIAGAIGWQSTVRLYLIVMAVFAIVMFFLGDAKEP------KVKIPLVAQ 195

Query: 195 -------RGVFLLSLANFLGLGAFFAMLTFLVSYLVSR------GVGMEKASLMFSMLSL 241
                     + LS   F+  G+F A   FL  YLV          G+ +A +  ++ + 
Sbjct: 196 TKDLLKDLRTYYLSFWYFITFGSFVAFGIFLPKYLVDHYELTTVDAGI-RAGIFIAIATF 254

Query: 242 VGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSV-----G 296
           +  LG II     D +  V  L    L  ++  +++ I + + L  +G +  SV      
Sbjct: 255 LRPLGGIIG----DKIDAVKALKVDFLFMIIGAIILGIANDMILFTVGCLTVSVCAGIGN 310

Query: 297 GIMTAYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYS-LALLSVPLAYL 355
           G++     +   +E  GV  G V+M+G  G    P ++ ++    G S LA + + L  +
Sbjct: 311 GLVFKLVPQYFQKE-AGVANGIVSMMGGLGGFFPPLVITYVTSITGTSHLAFIFLALFGV 369

Query: 356 VSAV 359
           ++ V
Sbjct: 370 LALV 373


>gi|11499136 conserved hypothetical protein [Archaeoglobus fulgidus]
           >gi|7430263|pir||D69442 conserved hypothetical protein
           AF1541 - Archaeoglobus fulgidus
           >gi|2649020|gb|AAB89705.1| (AE000996) conserved
           hypothetical protein [Archaeoglobus fulgidus]
           Length = 372
           
 Score = 71.8 bits (173), Expect = 1e-11
 Identities = 86/375 (22%), Positives = 168/375 (43%), Gaps = 22/375 (5%)

Query: 1   MEKLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPA 60
           M+ ++++ L+SL     Y       S+    +   G+  A IGL+          +++ +
Sbjct: 5   MKFILLMGLVSLFGDITYE---GARSIVGPYLATFGLTAAAIGLITGFGEFAGYGLRLLS 61

Query: 61  GYIGDKIGRKKLLTISILGYSLSSALIVLT-RDYWDLVTVRALYGFFAGLYYAPAT-ALI 118
           GYI D+ G   LLT   LGYSL  A+ +L   +YW +  +  +          PA  A++
Sbjct: 62  GYIADRTGNYWLLTF--LGYSLILAIPLLAFANYWWIAALLIVAERLGKAIRTPARDAML 119

Query: 119 SELFRE-RKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMV 177
           S   ++  +G+  G       +G+ I PLIV       +++ AF+ L + + +V + L  
Sbjct: 120 SFATKQVGRGTGFGIHEAMDQVGAVIGPLIVFSALAGYTFKEAFIALFLPALLVILFLFA 179

Query: 178 AIKGEP----IKVEGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYLVSRGVGMEKAS 233
             K  P     ++E  + ++    +L SL  FL +  F +    L+SY ++  V ++   
Sbjct: 180 TWKLYPTPQRFEIEEQESRVEGSFWLYSLFVFLSVAGFLSFP--LLSYHLAGYVDLKLIP 237

Query: 234 LMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLI----PLG 289
           L++++   +  + ++I+G  YD +G  +++L   L  L+  L+ + PS + ++      G
Sbjct: 238 LLYALAMGIDAISALISGRCYDRIGLKTLMLVPLLTPLI--LLALHPSIIGVLVGVAAWG 295

Query: 290 LVLYSVGGIMTAYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYSLA--L 347
            V+     I  A  ++    +      G  N V       G  ++G+L D     L   +
Sbjct: 296 AVMGMHEAITRAAVADLTGVKKRSTAYGVFNTVFGVAMLAGGAVLGYLYDISAALLVGFV 355

Query: 348 LSVPLAYLVSAVIIG 362
           L V +A   + +++G
Sbjct: 356 LVVEVAAFATLLMLG 370


>pir||E83385 hypothetical protein PA2091 [imported] - Pseudomonas aeruginosa
           (strain PAO1) >gi|9948103|gb|AAG05479.1|AE004636_10
           (AE004636) hypothetical protein [Pseudomonas aeruginosa]
           Length = 427
           
 Score = 71.8 bits (173), Expect = 1e-11
 Identities = 80/355 (22%), Positives = 147/355 (40%), Gaps = 27/355 (7%)

Query: 31  IMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSLSSALIVLT 90
           I  DL  +  +  L +T L L  +L     G++ D+ G + L+       +L  A + L 
Sbjct: 56  IAADLDWDRGQSALPVTLLGLAVALSSPLKGWLVDRWGARALVLPLTAALALCLASLALA 115

Query: 91  RDYWDLVTVRALYGFFAGLYYAPATALISELFRERKGSALGFFMVGPAIGSGITPLIVVP 150
           R  W L  + AL G        P   ++   F  R+G+A G   +G  +G  +   +   
Sbjct: 116 RSGWQLYLLFALLGLLTP-GNIPYARILGGWFERRRGAAYGILGLGFGVGGPLALYLGSA 174

Query: 151 VALTLSWRYAFLVLSIMSSIVGILLMVAIKGE----------------PIKVEGVKFKIP 194
                 WR  FLV  ++  ++ + L+ A+  E                P    G  ++  
Sbjct: 175 CIDAFGWRATFLVYGLLEGLLALPLLYALFRERPGDLPQARRTPADALPGATPGQAWR-- 232

Query: 195 RGVFLLSLAN-FLGLGAFFAMLTFLVSYLVSRGVGMEKASLMFSMLSLVGILGSIIAGFL 253
              F L + N  LG+ A   ++   V  L  RG+  E A+ + + L +  I+     G+L
Sbjct: 233 SADFWLIVGNLILGVFAVTGVMVHGVPLLQERGLSREVATDVLAALWVGMIVSQPALGYL 292

Query: 254 YDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSVG-----GIMTAYTSEKAS 308
            D      + L +AL + L  L++++  P  L+   + L  +G     G    + S    
Sbjct: 293 LDRYDTPRIALPFALLAALGLLLLLLGGPPALLWGAVFLIGLGAGGETGTTQYFVSRYFG 352

Query: 309 RENLGVVMGFVNMVGF-FGATIGPYIVGFLIDRLG-YSLALLSVPLAYLVSAVII 361
             +  V+ G +    F    ++G +++G+  DR G Y+ + L +  A+ V+A ++
Sbjct: 353 LRHFSVIYGSIQPFTFAIAISLGSWLLGYFYDRAGSYAGSTLVLLGAFGVAAGLL 407


>dbj|BAB06030.1| (AP001515) unknown conserved protein [Bacillus halodurans]
           Length = 391
           
 Score = 71.8 bits (173), Expect = 1e-11
 Identities = 91/387 (23%), Positives = 169/387 (43%), Gaps = 30/387 (7%)

Query: 7   LILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDK 66
           +I  S+ +   +SH + +P L+P I + LG     IGL+++S      + ++P G + D 
Sbjct: 11  VIFYSVSFFLWFSHFVYLPILSPYI-EFLGGKYVYIGLVLSSYGFMQFVCRLPIGIVSDL 69

Query: 67  IGRKKLLTISILGYSLSSALIVLTRDYWDLVTV-RALYGFFAGLYYAPATALISELFRER 125
           + R+K   I  +G S +S  +    ++  LV + RAL G  A  +    T L S  F + 
Sbjct: 70  LKRRKPFIIFGMGTSAASCFLFALTEHLGLVLLARALAGVAAATWVV-FTVLFSSCFTDS 128

Query: 126 K----GSALGFFMV-GPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIK 180
           +     S++ F +V    +G  ++  +V     +L W   F +  ++S +   L ++  +
Sbjct: 129 RVHEAMSSISFIVVLAQLLGMIVSGFLVD----SLGWHAPFWIGGLLSLLGATLALLIYE 184

Query: 181 -----GEPIKVEGVKFKIPRGVFLLSLANFLGLGA----FFAMLTFLVSYLVSRGVGMEK 231
                G P+++  +   I     LL   +FL + A    F  M  FL +Y    G+  + 
Sbjct: 185 PNVKAGAPVQLGDLSSVIREP--LLLKVSFLSIIAHSIIFTTMFGFLPTYATRIGLNTQG 242

Query: 232 ASLMFSMLSLVGILGSIIAG-FLYDHLGKVSVL-LAYALNSLLTFLVIVIPS--PLFLIP 287
            S +     +   +G++  G  +   LGK + L +A+    + T L  +I +  PL ++ 
Sbjct: 243 LSFIVFAFMIPHAIGTLFLGNVIVPRLGKWNALNVAFLGTVVFTLLTPMIDTKVPLMVVQ 302

Query: 288 --LGLVLYSVGGIMTAYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYSL 345
              G  L  +  ++   + E  +RE     MG    +   G   GP++ G L   LG ++
Sbjct: 303 GFNGFFLGILFPLLLGMSIESIAREKRATAMGVYQALYAVGMFTGPFLAGILSASLGLAV 362

Query: 346 AL-LSVPLAYLVSAVIIGLDLRKTSYK 371
                  LA L S ++     R+  Y+
Sbjct: 363 GFYFCAGLALLASILVFVWKRRRAVYR 389


>emb|CAC08554.1| (AL121673) bA305P22.2 (novel protein) [Homo sapiens]
           Length = 456
           
 Score = 71.8 bits (173), Expect = 1e-11
 Identities = 84/375 (22%), Positives = 155/375 (40%), Gaps = 52/375 (13%)

Query: 12  LGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKK 71
           LG    Y  R ++P     + +D G N  E G++++S    Y L QV  G++GD+IG +K
Sbjct: 52  LGTCLLYCARSSMPICTVSMSQDFGWNKKEAGIVLSSFFWGYCLTQVVGGHLGDRIGGEK 111

Query: 72  LLTISILGY----SLSSALIVLTRDYWDLVTV-RALYGFFAGLYYAPATALISELFRERK 126
           ++ +S   +    +++  L  L+  +   +T  R L G   G+Y+   T+L+S+  RE +
Sbjct: 112 VILLSASAWGSITAVTPLLAHLSSAHLAFMTFSRILMGLLQGVYFPALTSLLSQKVRESE 171

Query: 127 ----------GSALGFFMVGPAIGS------GITPLIVVPVALTLSWRYAFLVLSIMSSI 170
                     GS  G  + G A+GS      G   +      LTL W +      +    
Sbjct: 172 RAFTYSIVGAGSQFGTLLTG-AVGSLLLEWYGWQSIFYFSGGLTLLWVWYVYRYLLSEKD 230

Query: 171 VGILLMVAIKGEPI----KVEGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYLVSRG 226
           + + L V  +  P+    +V   +      V+   ++      +FF +L++L ++     
Sbjct: 231 LILALGVLAQSRPVSRHNRVPWRRLFRKPAVWAAVVSQLSAACSFFILLSWLPTFF--EE 288

Query: 227 VGMEKASLMFSMLS-LVGILGSIIAGFLYDHLGK------------------VSVLLAYA 267
              +    +F+++  LV I  S+ +GFL DHL                    +S + A  
Sbjct: 289 TFPDAKGWIFNVVPWLVAIPASLFSGFLSDHLINQGYRAITVRKLMQGMGLGLSSVFALC 348

Query: 268 LNSLLTFLVIVIPSPLFLIPLGLVLYSVGGIMTAYTSEKASRENLGVVMGFVNMVGFFGA 327
           L    +F   V+        +GL  ++  GI  +   +  +    G + G  N  G    
Sbjct: 349 LGHTSSFCESVV---FASASIGLQTFNHSGI--SVNIQDLAPSCAGFLFGVANTAGALAG 403

Query: 328 TIGPYIVGFLIDRLG 342
            +G  + G+L++  G
Sbjct: 404 VVGVCLGGYLMETTG 418


>sp|P44535|YDEA_HAEIN HYPOTHETICAL PROTEIN HI0135 >gi|1074278|pir||E64143 chloramphenicol
           resistance protein homolog HI0135 - Haemophilus
           influenzae (strain Rd KW20) >gi|1573088|gb|AAC21806.1|
           (U32699) conserved hypothetical transmembrane protein
           [Haemophilus influenzae Rd]
           Length = 396
           
 Score = 71.4 bits (172), Expect = 2e-11
 Identities = 81/370 (21%), Positives = 159/370 (42%), Gaps = 42/370 (11%)

Query: 6   ILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGD 65
           +LI+   G+IFN +  + V  L+ I  +   +  A+ GL+MT       ++ +PA     
Sbjct: 15  VLIMACAGFIFNTTEFVPVAMLSDIA-QSFDMQTADTGLMMTVYAWTVLIMSLPAMLATG 73

Query: 66  KIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELF-RE 124
            + RK LL    + + +   L V+  ++W L+  R        ++++   +L+  +  + 
Sbjct: 74  NMERKSLLIKLFIIFIVGHILSVIAWNFWILLLARMCIALAHSVFWSITASLVMRISPKH 133

Query: 125 RKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKGEPI 184
           +K  ALG   +G A+ + +   I   V   + WR  F ++++++  +  L++  +   P 
Sbjct: 134 KKTQALGMLAIGTALATILGLPIGRIVGQLVGWRVTFGIIAVLALSIMFLIIRLLPNLPS 193

Query: 185 KVEGVKFKIP----RGVFL-LSLANFLGLGAFFAMLTFLVSYLVSRG-VGMEKASLMFSM 238
           K  G    +P    R + L L +   + + A F   T++  +++  G +    A+ +  +
Sbjct: 194 KNAGSIASLPLLAKRPLLLWLYVTTAIVISAHFTAYTYIEPFMIDVGHLDPNFATAVLLV 253

Query: 239 LSLVGILGSIIAGFLYDHLGKVSV-----LLAYALNSLL--TFLVIVIPSPLFLIPLGL- 290
               GI  S++   LY       +     LL ++L  LL  T  +I + S +F+  +G+ 
Sbjct: 254 FGFSGIAASLLFNRLYRFAPTKFIVVSMSLLMFSLLLLLFSTKTIIAMFSLVFIWGIGIS 313

Query: 291 ----------------------VLYSVGGIMTAYTSEKASRENLGVVMGFVNMVGFFGAT 328
                                  +YS  GI  A     A   NL      +N +G+ GA 
Sbjct: 314 CIGLSLQMRVLKLAPDATDVATAIYS--GIFNAGIGAGALFGNLATTYLGLNEIGYTGAA 371

Query: 329 IGPYIVGFLI 338
           +G  ++GF+I
Sbjct: 372 LG--LIGFII 379


>gb|AAC15508.1| (L49465) hypothetical metabolite transport protein [Pseudomonas
           fluorescens]
           Length = 405
           
 Score = 71.4 bits (172), Expect = 2e-11
 Identities = 78/330 (23%), Positives = 137/330 (40%), Gaps = 38/330 (11%)

Query: 61  GYIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISE 120
           G++ D+IGRKK+L  ++L + + S        Y  L+ VR + G   G       AL +E
Sbjct: 66  GWVADRIGRKKILVGAVLLFGVFSLCTAYVESYSSLLLVRFMTGLGLGAALPNLIALCAE 125

Query: 121 LFRER-KGSALGFFMVGPAIG---------------------SGITPLIVVP-VALTLSW 157
              ER +G+A+     G  +G                      G+TPL+VVP +AL L  
Sbjct: 126 AVSERHRGTAISVMYCGVPLGGALAAVVAMFSSEHWQTTFIIGGLTPLLVVPLMALLLPE 185

Query: 158 RYAFLVLSIMSSIVGILLMVAIKGEPIKVEGVKFKIPRGVFLLSLANFLGLGAFFAMLTF 217
             AF    + ++        A+ GE            R    L L+ F  L   + +L +
Sbjct: 186 STAFRQQHVTTASPRSSTAQALFGE---------GRARCTLALWLSYFFTLTVMYMLLNW 236

Query: 218 LVSYLVSRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLL---AYALNSL--L 272
           L S L+ +G    +A ++  + ++ G +GS++ G + D    + V+L   A  L +L  +
Sbjct: 237 LPSLLLEQGFTKPQAGMVQMLFNIGGAMGSLLGGVMLDRCNGLKVVLFVYAGVLAALAGV 296

Query: 273 TFLVIVIPSPLFLIPLGLVLYSVGGIMTAYTSEKASRENLGVVMGFVNMVGFFGATIGPY 332
              V ++P  +    +GL + +   ++ A              +G    +G  G+  GP 
Sbjct: 297 GLSVGIVPMAIAGFAVGLFVMAAQLVLYALAPPSYPTSVRATGVGAAVAIGRLGSVAGPL 356

Query: 333 IVG-FLIDRLGYSLALLSVPLAYLVSAVII 361
             G  L    G +  LL+     +++A+ I
Sbjct: 357 AAGQILAAGAGTTGVLLATSPGLVIAALSI 386


>pir||F71848 probable transporter - Helicobacter pylori (strain J99)
           >gi|4155704|gb|AAD06687.1| (AE001538) putative
           transporter [Helicobacter pylori J99]
           Length = 443
           
 Score = 71.4 bits (172), Expect = 2e-11
 Identities = 80/350 (22%), Positives = 159/350 (44%), Gaps = 39/350 (11%)

Query: 42  IGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRA 101
           +GL +    L   + Q P G + DKIGRK ++ + +L + + S +  +  D   LV  R 
Sbjct: 41  VGLAVGGAYLTQIIFQTPMGILSDKIGRKVVVMVCLLLFLIGSLVCFVANDIITLVIGRF 100

Query: 102 LYGFFA--GLYYAPATALISELFRERKGSALGFFM-----VGPAIGSGITPLIVVPVALT 154
           + G  A  G+  A     + E  R +  + +G F+     +  AIG G+       VA  
Sbjct: 101 IQGMGALGGVVSAMVADEVKEEERTKAMAIMGAFIFISFTISMAIGPGV-------VAFL 153

Query: 155 LSWRYAFLVLSIMSSIVGILLMVAIKGEP---IKVEGVKFKIP--RGVFLLSLANFLGLG 209
              ++ FL+ +I+ +++ +L+++ +K  P    +++ +K   P  + ++LL L++F    
Sbjct: 154 GGAKWLFLLTAIL-TLLSLLMLLKVKDAPKISYQIKNIKAYQPNSKALYLLYLSSFFE-K 211

Query: 210 AFFAMLTFLVSYLVSRGVGMEKASLMFSML--SLVGILGSIIAGFLYDHLGK-VSVLLAY 266
            F  ++  L+   +      +++ L+   +  +L+G+L   IA  + +   K   V+L+ 
Sbjct: 212 MFMTLIFVLIPLALVNEFHKDESFLILVYVPGALLGVLSMGIASVMAEKYNKPKGVMLSG 271

Query: 267 ALNSLLTFLVIVIPSP------LFLIPLGLVLYSVG-----GIMTAYTSEKASRENLGVV 315
            L  ++++L + +         L+L  +G+  + +G      IM +  S+ A     G V
Sbjct: 272 VLLFIVSYLCLFLADSSFLGKYLWLFIVGVAFFFIGFATLEPIMQSLASKFAKVHEKGKV 331

Query: 316 MGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVIIGLDL 365
           +G     G+ G+ +G    G     LG S    +  L  +   +I GL L
Sbjct: 332 LGQFTTFGYLGSFVGGVSGGLSYHHLGVS----NTSLIIVALGLIWGLSL 377


>pir||B83180 probable MFS transporter PA3718 [imported] - Pseudomonas aeruginosa
           (strain PAO1) >gi|9949884|gb|AAG07105.1|AE004791_2
           (AE004791) probable MFS transporter [Pseudomonas
           aeruginosa]
           Length = 413
           
 Score = 71.4 bits (172), Expect = 2e-11
 Identities = 82/350 (23%), Positives = 157/350 (44%), Gaps = 22/350 (6%)

Query: 29  PIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSLSSALIV 88
           P + +  G + A +  +M++         + AG +  + G ++LLT  +     +S L  
Sbjct: 43  PSLQRSFGGDLAALSWIMSAFPFVGVFGGIAAGLLVRRWGDRRLLTGGLAILGGASLLGA 102

Query: 89  LTRDYWDLVTVRALYGFFAGLYYAPATALISELFRERKGSALGFFMVGPAIGSGITPLIV 148
             +D+  L+  R + G    +    A A++  +  E + S +  F +     +G   L +
Sbjct: 103 SMQDFTWLLATRFVEGLGFLIVVVAAPAVLHRITSETRRSVV--FGLWSTFMAGGIALSM 160

Query: 149 VPVALTLSWRYAFLVLSIMSSIVGILLMVAIKGEP-IKVEGVK-------FKIPRGVFLL 200
           +   L   WR  + + +++  +  +LL +++  +   +  GV+        K+P  + LL
Sbjct: 161 LFGPLLADWRADWQLSALLVLVAALLLPLSVPADDGCRAAGVRPAGLGTLLKVP-AITLL 219

Query: 201 SLANFLGLGAFFAMLTFLVSYLVSR-GVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGK 259
           +L        FFA++TFL  +L+ R GV +E A L+ + +     LG++ AGF+     +
Sbjct: 220 ALGFTTYNLQFFALMTFLPVFLMQRLGVALETAGLIGAAIVAANALGNVAAGFILSRGIR 279

Query: 260 VSVLLAY-ALNSLLT---FLVIVIPSPLFLIPLGLVLYSVGGIMTAYTSEKASRENLG-- 313
              LLA  A+   LT   F    +P  L  I LG V  +V G++       A   +    
Sbjct: 280 PGALLASTAILMGLTGAAFFHAAMPG-LLAIALGFVFSAVAGMLPTTVLATAPLASPAPS 338

Query: 314 ---VVMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVI 360
              + +G+V    + G  IGP ++G ++ R  +S A+  + +A    AV+
Sbjct: 339 LTPLAIGWVMQGNYLGQVIGPLLIGLIVSRFDWSGAIGLMLVAGAAGAVL 388


>dbj|BAB07028.1| (AP001518) multidrug resistance protein [Bacillus halodurans]
           Length = 403
           
 Score = 71.4 bits (172), Expect = 2e-11
 Identities = 84/385 (21%), Positives = 165/385 (42%), Gaps = 33/385 (8%)

Query: 6   ILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVP-AGYIG 64
           ++ L S+  +    + M +P L PII ++L I++ ++ LL+T   +  ++I +P AGY+ 
Sbjct: 9   LMSLASIPLVMTLGNSMLIPVL-PIIERELDISSLQVSLLITVYSV-VAIIFIPIAGYLS 66

Query: 65  DKIGRKKLLTISIL-----GYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALIS 119
           D IGRKK++  S++     G     A       Y  ++  R L G  A         L+ 
Sbjct: 67  DIIGRKKVIIPSLILAAIGGVISGFAAWKSPSPYTMILVGRLLQGIGAAGAAPIVMPLVG 126

Query: 120 ELFRERK--GSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMV 177
           +LF++ K     LG        G  ++P++   +A T+ W   F  + +      +L++ 
Sbjct: 127 DLFQQEKEVSRGLGIIETSNTFGKVLSPILGAYLA-TIVWYLPFWAIPLFCLFSILLMLF 185

Query: 178 AIKGEPIKVEGVKFKI------------PRGVFLLSLANFLGLGAFFAMLTFLVSYLVSR 225
            +K E    E V F+              R ++ + +   + +   F +L +L + L  R
Sbjct: 186 LVKTEKETKEPVPFQTFIQTIKTIFKREGRWLYAVFVVGCICMFLLFGILFYLSTMLEER 245

Query: 226 G--VGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLV--IVIPS 281
               G++K  ++   L+ + I       ++ +   K+  +    L +LLT     I+   
Sbjct: 246 YQIEGVKKGVVLAIPLAALCIASLATGRWIEEDKAKMKWMSVLGL-ALLTASTAWIIFSE 304

Query: 282 PLFLIPLGLVLYSVGGIMT-----AYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGF 336
            ++++  GL +  +G  MT     A  +E   +E  G +    N + F G   GP +   
Sbjct: 305 SIYVLLAGLFISGIGIGMTLPSLDALVTEGIHKEQRGTITSLYNSMRFVGVAFGPPLFAL 364

Query: 337 LIDRLGYSLALLSVPLAYLVSAVII 361
           L+        +++   A+L   +I+
Sbjct: 365 LMKTSHSITFMVNAITAFLTMLLIL 389


>gb|AAB81315.1| (U89712) putative 3-(3-hydroxyphenyl) propionate transport protein;
           HppK [Rhodococcus globerulus]
           Length = 453
           
 Score = 71.0 bits (171), Expect = 2e-11
 Identities = 52/171 (30%), Positives = 86/171 (49%), Gaps = 4/171 (2%)

Query: 27  LAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSLSSAL 86
           +AP + K   I++ EIG L+++ ++  +L  +    + DKIGR++L    ++G ++  AL
Sbjct: 40  VAPHLGKSWDISSVEIGYLLSAGIIGTALGAIFISPLADKIGRRRLAIWCLVGITVGMAL 99

Query: 87  IVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRE-RKGSALGFFMVGPAIGSGITP 145
                +   L+  RA  G   G   A    L+SE   + R+G+ALG + VG  +G  +  
Sbjct: 100 SACAVNVPQLIAFRAFAGLGIGGLVANLNVLVSEFSSDKRRGTALGIYGVGYPLGGAVGG 159

Query: 146 LIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKGEPIKVEGVKFKIPRG 196
            I   +     WR AF+  +I   I  I+L+V IK  P  +E +  K P G
Sbjct: 160 AISGVLISVFDWRSAFIFGTI---ITAIMLVVVIKTLPESIEFLIEKRPVG 207


>pir||E64667 multidrug-efflux transporter - Helicobacter pylori (strain 26695)
           >gi|2314341|gb|AAD08227.1| (AE000624) multidrug-efflux
           transporter [Helicobacter pylori 26695]
           Length = 443
           
 Score = 71.0 bits (171), Expect = 2e-11
 Identities = 81/350 (23%), Positives = 159/350 (45%), Gaps = 39/350 (11%)

Query: 42  IGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRA 101
           +GL +    L   + Q P G + DKIGRK ++ + +L +   S +  +  D   LV  R 
Sbjct: 41  VGLAVGGAYLTQIVFQTPMGILSDKIGRKVVVMVCLLLFLAGSLVCFIANDIVWLVIGRF 100

Query: 102 LYGFFA--GLYYAPATALISELFRERKGSALGFFM-----VGPAIGSGITPLIVVPVALT 154
           + G  A  G+  A     + E  R +  + +G F+     +  AIG G+       VA  
Sbjct: 101 IQGMGALGGVISAMVADEVKEEERTKAMAIMGAFIFISFTISMAIGPGV-------VAFL 153

Query: 155 LSWRYAFLVLSIMSSIVGILLMVAIKGEP---IKVEGVKFKIP--RGVFLLSLANFLGLG 209
              ++ FL+ +I+ +++ +L+++ +K  P    +++ +K   P  + ++LL L++F    
Sbjct: 154 GGAKWLFLLTAIL-TLLSLLMLLKVKDAPKISYQIKNIKAYQPNSKALYLLYLSSFFE-K 211

Query: 210 AFFAMLTFLVSYLVSRGVGMEKASLMFSML--SLVGILGSIIAGFLYDHLGK-VSVLLAY 266
           AF  ++  L+   +      +++ L+   +  +L+G+L   IA  + +   K   V+L+ 
Sbjct: 212 AFMTLIFVLIPLALVNEFHKDESFLILVYVPGALLGVLSMGIASVMAEKYNKPKGVMLSG 271

Query: 267 ALNSLLTFLVIVIPSP------LFLIPLGLVLYSVG-----GIMTAYTSEKASRENLGVV 315
            L  ++++L + +         L+L  +G+  + +G      IM +  S+ A     G V
Sbjct: 272 VLLFIVSYLCLFLADSSFLGKYLWLFIVGVAFFFIGFATLEPIMQSLASKFAKVHEKGKV 331

Query: 316 MGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVIIGLDL 365
           +G     G+ G+ +G    G     LG S    +  L  +   +I GL L
Sbjct: 332 LGQFTTFGYLGSFVGGVSGGLSYHHLGVS----NTSLIVVALGLIWGLSL 377


>emb|CAB93456.1| (AL357591) putative integral membrane transport protein
           [Streptomyces coelicolor A3(2)]
           Length = 462
           
 Score = 71.0 bits (171), Expect = 2e-11
 Identities = 87/349 (24%), Positives = 158/349 (44%), Gaps = 57/349 (16%)

Query: 61  GYIGDKIGRKKLLTISILGYSLSSALIVLTRDY-----WD---LVTVRALYGFFAGLYYA 112
           G +GD++GR+K+L ++++  +  +  I L   Y     W    L+  R + GF  G  YA
Sbjct: 98  GPLGDRVGRQKVLAVTMIMMAAGTFAIGLIPSYATIGVWAPVLLLAARLVQGFSTGGEYA 157

Query: 113 PATALISELFRERKGSALGFF-----MVGPAIGSGITPLIVVPVA----LTLSWRYAFLV 163
            A+  I+E   +++   LG +     + G   G+G+  L+   ++    ++  WR  FL+
Sbjct: 158 GASTFIAEYAPDKRRGFLGSWLEFGTLAGYIGGAGLVTLMTALLSDGDLMSWGWRIPFLI 217

Query: 164 LSIMSSIVGILLMV------AIKGEPIKVEGVKFKIPRGVFLL----SLANFLGLGAFFA 213
              M  IVG+ L +      A   E  K E  + K+P    +     +L   +GL   F 
Sbjct: 218 AGPM-GIVGLYLRMRLEETPAFAAEVAKAETARVKVPLREMVTGQWRALLLCVGLVLVFN 276

Query: 214 MLTF-LVSYLVSRGVGMEKASLMFSMLSLVGILGSII-----AGFLYDHLGKVSVLLAYA 267
           +  + L+SY+ S      K      +L ++G++  ++     AG L D +G+  V+ A  
Sbjct: 277 VTDYMLLSYMPSYLTSELKYDETHGLLVVLGVMTLMMVVQPFAGALTDRVGRRPVIAA-- 334

Query: 268 LNSLLTFLVIVIPSPLF-----LIPLGLVLYSVGGIMTAYTSEKAS--------RENLG- 313
                 FL++ +P+ L      L+ + L + ++G ++  +T+   S        R   G 
Sbjct: 335 --GCAGFLLLSVPALLLIREGSLLAVALGMGALGLLLVCFTASMPSALPALFPTRVRYGS 392

Query: 314 VVMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVIIG 362
           + +GF   V  FG T  P +V  LI   G     + +P  YL++A ++G
Sbjct: 393 LSIGFNVSVSLFGGTT-PLVVTALIGATGD----MMMPAYYLMAAAVVG 436


>emb|CAB71269.1| (AL138598) putative integral membrane efflux protein. [Streptomyces
           coelicolor A3(2)]
           Length = 521
           
 Score = 70.6 bits (170), Expect = 3e-11
 Identities = 85/358 (23%), Positives = 154/358 (42%), Gaps = 42/358 (11%)

Query: 29  PIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSLSSALIV 88
           P I KDL   ++++  ++ S  L +  + + AG + D+ GRK+LL++ +  ++L+S    
Sbjct: 36  PSIQKDLDATSSQLQWMVDSYALAFGGLLLMAGGLSDRFGRKRLLSVGLGAFALTSLGAA 95

Query: 89  LTRDYWDLVTVRALYGFFAGLYYAPATALISELF-RERKGSALGFFMVGPAIGSGITPLI 147
              +   L+T RAL G  A L      A+I ++F RE +G A+G +    A+G  + PL+
Sbjct: 96  FASNAEMLITFRALMGISAALMMPATLAIIKDVFPREEQGKAIGIWSGAAAVGVPLGPLV 155

Query: 148 VVPVALTLSWRYAFLV---LSIMSSIVGILLMVAIKGE---PIKVEGVKFKIPRGVFLL- 200
              +     W   FL+   L+ ++ I G  L+   K E    + + G    +   V ++ 
Sbjct: 156 SGLLLEHFWWGSMFLINVPLAAIALIGGAKLIPESKAEGHPGLDLVGALLSVAGLVAIVY 215

Query: 201 --------SLANFLGLGAFFAMLTFLVSYLVSRGVGMEKASLMFSMLSLVGILGSIIAGF 252
                      + + LG+ F  +  +V+++      + +      ML +   L +   G 
Sbjct: 216 GLVEAPHNGWGDIITLGSLFVGVVLMVAFV------LWERKTAHPMLDVGLFLNARYGG- 268

Query: 253 LYDHLGKVSV-LLAYALNSLLTFLVIVIPSPLFLIPL--GLVLYSVGGIMTAYTSEKASR 309
                G +++   ++ L S L  L   + S L L PL  GL + ++G +M          
Sbjct: 269 -----GALAIACTSFGLYSGLYLLTQYLQSVLELDPLGAGLRMLAIGTMMVGAPLSAKLV 323

Query: 310 ENLG----VVMGFVNMVGFFGATIG-------PYIVGFLIDRLGYSLALLSVPLAYLV 356
           E  G    VV+G +      G   G         ++G  +  LG  +AL +   A LV
Sbjct: 324 ERTGLKATVVVGLLLCAAGLGVLAGLSVDDETQALIGLAVFGLGMGIALPAAVDAILV 381


>pir||E81862 probable integral membrane transporter NMA1673 [imported] -
           Neisseria meningitidis (group A strain Z2491)
           >gi|7380315|emb|CAB84901.1| (AL162756) putative integral
           membrane transporter [Neisseria meningitidis Z2491]
           Length = 461
           
 Score = 70.6 bits (170), Expect = 3e-11
 Identities = 97/354 (27%), Positives = 154/354 (43%), Gaps = 43/354 (12%)

Query: 38  NNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLV 97
           N   +GL M    L  +L+Q+P G   DK GRKK + + ++ ++  S L         LV
Sbjct: 52  NKTLVGLAMGIYGLTQALLQLPLGIASDKFGRKKTIYVGLIVFAAGSFLAAAADTLPMLV 111

Query: 98  TVRALYGFFAGLYYAPATALISELFRERKGSALGFFMVGPAIGSGIT-PLIVVPV-ALTL 155
             RA+ G  AG   A  TAL+++L R+   +     M+G +IG   +  L+V PV A  +
Sbjct: 112 AARAIQG--AGAVSAAVTALLADLTRDGVRTR-AMAMIGLSIGLTFSVSLVVAPVIADAV 168

Query: 156 SWRYAFLVLSIMS-SIVGILLMVAIKGEPIKVE----------GVKFKIPR------GVF 198
             R  FL+  I++ + +G++  +    E  K+           G   K  R      G+F
Sbjct: 169 GVRGLFLLTGILTVASIGVVAWMTPDPEVSKLHEDTQAQPSRIGEVLKNRRLLTLDFGIF 228

Query: 199 LLSLANFLGLGAFFAMLTFLVSYLVSRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLG 258
            L  A      A F  L F ++ L    +   K  L  ++  LV ++  II G   + L 
Sbjct: 229 ALHAAQM----ALFTALPFAMTQLGLEKIQHWKVYLPSTITGLVVMVPLIIVGETRNKLK 284

Query: 259 KVSVL----LAYALNSLLTFLVIVIPSPLFLIPLGLVLYSVG-----GIMTAYTSEKASR 309
           +V +L    +A A   LL+ +       + LI   LV+Y +G       + +  S+ A  
Sbjct: 285 QVFILGIACIAAAQLGLLSGM-----RSVGLITAYLVVYFIGFNVLEASLPSMVSKIAPS 339

Query: 310 ENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYS--LALLSV-PLAYLVSAVI 360
           +  G  MG  N +   G   G    G L  + G+S   A  S+  L +LV AV+
Sbjct: 340 DLKGTAMGVYNTMQSLGLFAGGVAGGLLFQKYGFSGVFAFCSILMLLWLVIAVL 393


>gb|AAG19033.1| (AE005003) multidrug resistance protein homolog; YfmO1
           [Halobacterium sp. NRC-1]
           Length = 412
           
 Score = 70.6 bits (170), Expect = 3e-11
 Identities = 87/354 (24%), Positives = 144/354 (40%), Gaps = 24/354 (6%)

Query: 24  VPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSLS 83
           V  + P I K+LG ++  +  L TS LL   L  + AG +  +IG K  + + I   ++ 
Sbjct: 50  VDPILPSIAKELGADHFMVMFLFTSYLLVTGLANLVAGTLATRIGSKNTMLVGIGIVAVF 109

Query: 84  SALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRERKGSALGFFMVGPAIGSGI 143
           +    L      +  +R  +G    L+   A A+I  +     G A+  +      G   
Sbjct: 110 AGGCALVSSVESMAVLRGFWGLGNALFTTTALAIIVGVSAGNSGRAITLYEAALGFGIAC 169

Query: 144 TPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKGEPIKV--EGVKFKI----PRGV 197
            PL+   +    SWR  F   S++  ++G + +     EP     EGV+  I      GV
Sbjct: 170 GPLLGGFLG-AQSWRLPFAGTSVL-MLLGFVFVATTVTEPDTEGREGVRALIGTFRHTGV 227

Query: 198 FLLSLANFLGLGAFFAMLTFLVSYLVSRGVGMEKASLMFSMLSLVGILGS-IIAGFLYDH 256
              ++   L    FF +L +  + LV  G    +  L+F    L+ I+GS ++A  L   
Sbjct: 228 RTNAIVGMLYTYGFFTVLAY--TPLVLEGFTTMQIGLVFFAWGLLVIVGSAVLAPRLNAR 285

Query: 257 LGKVSVLLAYALNSLLTFLVI--VIPSPLFLIPLGLVLYSVGGIMTAYTSEKA---SREN 311
            G   V  A AL +    L +  ++ SP+ L  L +      G++ A  S  A   S  +
Sbjct: 286 FGTPEVASA-ALTAFAALLCLMWLVSSPMVLAGLVVTAGLACGLLNANLSTLAMGISTHS 344

Query: 312 LGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVIIGLDL 365
                G  N + F G    P + G++    G         L +L+ A +I L L
Sbjct: 345 RPSASGAYNSLRFTGGAFAPIVAGYIGGNYG-------AALPFLLGAAVITLGL 391


>sp|Q51955|PCAK_PSEPU 4-HYDROXYBENZOATE TRANSPORTER >gi|1147822|gb|AAA85137.1| (U10895)
           PcaK [Pseudomonas putida]
           Length = 448
           
 Score = 70.2 bits (169), Expect = 4e-11
 Identities = 89/401 (22%), Positives = 164/401 (40%), Gaps = 71/401 (17%)

Query: 23  AVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISIL---G 79
           A+  +AP + ++ GI+ A +G +M++ L+      + +G + D+ GRK +L  ++L   G
Sbjct: 47  AMGFIAPALSQEWGIDRASLGPVMSAALIGMVFGALGSGPLADRFGRKGVLVGAVLVFGG 106

Query: 80  YSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRERKGSALGF-----FM 134
           +SL+SA      +   L+ +R L G   G     AT L+SE   ER  S L       F 
Sbjct: 107 FSLASA---YATNVDQLLVLRFLTGLGLGAGMPNATTLLSEYTPERLKSLLVTSMFCGFN 163

Query: 135 VGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIK-------------- 180
           +G A G G     ++P      W    ++  ++  ++ ++LMV +               
Sbjct: 164 LGMA-GGGFISAKMIP---AYGWHSLLVIGGVLPLLLALVLMVWLPESARFLVVRNRGTD 219

Query: 181 ---------GEPIKVEGVKFKIPR--------------------GVFLLSLANFLGLGAF 211
                       +  E   F +P                     G  LL L  F+GL   
Sbjct: 220 KIRKTLSPIAPQVVAEAGSFSVPEQKAVAARSVFAVIFSGTYGLGTMLLWLTYFMGLVIV 279

Query: 212 FAMLTFLVSYLVSRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVL-LAYALNS 270
           + + ++L + +   G  ME+A+ + ++    G+L ++  G+  D      V+ + Y L  
Sbjct: 280 YLLTSWLPTLMRDSGASMEQAAFIGALFQFGGVLSAVGVGWAMDRYNPHKVIGIFYLLAG 339

Query: 271 LLTFLV------IVIPSPLFLIPLGLVLYSVGGIMTAYTSEKASRENLGVVMGFVNMVGF 324
           +  + V      I + + L LI  G+ +      M +  +     +     + ++  +G 
Sbjct: 340 VFAYAVGQSLGNITVLATLVLI-AGMCVNGAQSAMPSLAARFYPTQGRATGVSWMLGIGR 398

Query: 325 FGATIGPYIVGFLIDRLGYS----LALLSVPLAYLVSAVII 361
           FGA +G +    L+  LG++    L  L VP A     VI+
Sbjct: 399 FGAILGAWSGATLLG-LGWNFEQVLTALLVPAALATVGVIV 438


>gb|AAK42225.1| Metabolite transport protein [Sulfolobus solfataricus]
           Length = 427
           
 Score = 70.2 bits (169), Expect = 4e-11
 Identities = 87/349 (24%), Positives = 150/349 (42%), Gaps = 43/349 (12%)

Query: 61  GYIGDKIGRKKLLTISILGYSLSSALIVLTRDY--------WDLVTVRALYGFFAGLYYA 112
           G++GDKIGRK  L I++    LSS    L   Y          L  +R L GF  G  + 
Sbjct: 68  GHLGDKIGRKYTLIITMTLMGLSSLFTGLLPGYAILGVLAPTLLTILRLLQGFSLGGEFG 127

Query: 113 PATALISELFRERK-----GSALGFFMVGPAIGSG---ITPLIVVPVAL-TLSWRYAFLV 163
               L +E     K     G A     +GP + +G   +   I++P A  ++ WR  F++
Sbjct: 128 GGITLSAEFAEPGKRAFYTGIAQMAQGIGPLMATGLIFVFSSIMLPSAFASIGWRILFII 187

Query: 164 LSIMSSIVGILLMVAIKGEPI------KVEGVKFKIPRGVFLLSLANFLGLGAF------ 211
            + + +++G+++ + I   P+      K E   F +     +      LGLG        
Sbjct: 188 GAFI-AVIGVMIRLKISESPVFKKVKEKNEISHFPLVDAFRIYWKRILLGLGFIIGGTTM 246

Query: 212 -FAMLTFLVSYLVS-RGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALN 269
            +A   F  SYL +  GV     SL  ++  +V  +  ++   L D +G+  +++A A+ 
Sbjct: 247 TYATSVFASSYLENVIGVPARLVSLALTIGYIVEAISILLFAMLADKVGRKPLMVATAVG 306

Query: 270 SLL---TFLVIVIPSPLFLIPLGLVLYSVGGIMTAYTSEKASRENLGVVMGFVNM----- 321
            L+    + +++      LI L  ++YSV G M+      A  E     + +  +     
Sbjct: 307 LLILVYPYFLLISTGQFSLILLAQIMYSVIGSMSTGAYATALTELFPTKVRYTALSFDYH 366

Query: 322 --VGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVIIGLDLRKT 368
             V  FG T  P+I  +LI   GY LA +   +A ++  +I  L  ++T
Sbjct: 367 VGVAVFGGTT-PFIASYLIYATGYKLAPVYWGIAGMILTLIAYLLYKET 414


>pir||S74875 quinolone resistance protein norA - Synechocystis sp.  (strain PCC
           6803) >gi|1652918|dbj|BAA17836.1| (D90909) quinolene
           resistance protein NorA [Synechocystis sp.]
           Length = 418
           
 Score = 70.2 bits (169), Expect = 4e-11
 Identities = 91/393 (23%), Positives = 165/393 (41%), Gaps = 31/393 (7%)

Query: 2   EKLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAG 61
           +K   L+  S+  +F  S    +P+L P+  +D+G    ++G +M S  L     ++  G
Sbjct: 15  QKTFALLFASV-LMFWLSLTALLPTL-PMYAQDVGATKQQVGWIMGSFALGLLGSRIWIG 72

Query: 62  YIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISEL 121
            + D+ GRK  + I  L  +L+    +LT     L+ +RA +G     Y     +L+ +L
Sbjct: 73  QLVDRRGRKIAIVIGALVVALAPLGYLLTATVGALMAIRAFHGICLAAYTTGYNSLVVDL 132

Query: 122 F-RERKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIK 180
              +++G  +G+  +   IG G  P +   ++ ++ + + F+  S++  I  +L +   +
Sbjct: 133 SPPQQRGEIIGYMSLAVPIGMGFGPAVGAYISQSIGYEFLFIASSLLGFISLVLALQVRE 192

Query: 181 GEP---IKVEGVKFKIPR----GVFLLSLAN------FLGLGAFFAMLTFLVSYLVSRGV 227
             P      E V    PR    G  L S +        L +G  F  L   +   V    
Sbjct: 193 NRPPDQSSAEDVFGDRPRPRSIGKLLTSRSMAVPTLVLLLIGLLFGNLATFLPLFVREID 252

Query: 228 GMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIP 287
               A + +S+ ++   +  +  G L D  G+   ++   +  LL+ + +      + + 
Sbjct: 253 LATYAGVFYSVAAIASFVPRLFLGSLADTYGRGLFIVGSLICYLLSMVCLAQADNSWELL 312

Query: 288 LGLVLYSVG-GIM----TAYTSEKASRENLGVVMGFVNMVGFFGA-TIGPYIVGFLIDRL 341
               L   G GI+     A  S+++S E  G V   V M GF G   I   I+G L +  
Sbjct: 313 TAAALEGAGSGILLPTTIALISDRSSLEERGRVFS-VCMSGFDGGIAIAAPIMGVLNEIF 371

Query: 342 GY--------SLALLSVPLAYLVSAVIIGLDLR 366
           GY         LAL ++ +  + S   IG  LR
Sbjct: 372 GYRHVFWLSGGLALAAIMVFGIFSNPTIGRSLR 404


>gb|AAB70881.1| (U86689) exuT [Pectobacterium chrysanthemi]
           Length = 345
           
 Score = 70.2 bits (169), Expect = 4e-11
 Identities = 43/163 (26%), Positives = 78/163 (47%), Gaps = 1/163 (0%)

Query: 9   LISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIG 68
           L+++G +  Y  R A+ + AP + + L I+  +   ++ +    Y+++Q  AGY+ D +G
Sbjct: 14  LVTIGTVLGYLTRNAIAAAAPTLQEQLHISTQQYSYIIAAYSACYTIMQPVAGYVLDVLG 73

Query: 69  RKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRERKGS 128
            K    +  + ++L  A   L   +  L   R   G              SE F  ++ S
Sbjct: 74  TKVGYAMFAILWALFCAGTALANSWGGLAVARGAVGMAEAAMIPAGLKASSEWFPAKERS 133

Query: 129 -ALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSI 170
            A+G+F VG +IG  + P +VV   +  SW+ AFL+   +S +
Sbjct: 134 VAVGYFNVGSSIGGMLAPPLVVWAIMAHSWQMAFLITGALSLV 176


>gb|AAK41393.1| Transport protein, permease [Sulfolobus solfataricus]
           Length = 371
           
 Score = 69.9 bits (168), Expect = 5e-11
 Identities = 89/356 (25%), Positives = 162/356 (45%), Gaps = 24/356 (6%)

Query: 16  FNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTI 75
           FN  ++ +  +L P++ +   ++  EI L  T   +  S+ Q   G+  DK G K++  I
Sbjct: 16  FNSLYQYSWNALEPLLREGFNVSVVEIALGFTLFSVFSSVFQPIGGHFADKQGPKRIGVI 75

Query: 76  SILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRERKGSALGFFMV 135
           S +  ++      L+ + +      ++     G+ Y  A  L  + FRER G A G   +
Sbjct: 76  SAILSAIGFLGTYLSPNIYVFFVSWSIGSIGEGILYGIAANLAMKWFRERMGFATGIVSM 135

Query: 136 GPAIGSGI-TPLIVVPVALTLSWRYAFLVLSI-MSSIVGILLMVAIKGEPIKVEGVKFKI 193
           G  IGS I  P I      +++  Y  + L+I +  IV + +++ I   P K+ G   + 
Sbjct: 136 GFGIGSAIANPFI------SMAGNYRIVTLAIGLVEIVLLPILLYISDYPPKLSG---QT 186

Query: 194 PRGVFL--LSLANFLGLGAFFAMLTFLVSYLVSRGVGMEKASLMFSMLSLVGILGS---I 248
           PR   L       +L        LT L S L   G G+ +  L+ +++S++ +L      
Sbjct: 187 PRQAVLSVKFWLIYLSFATSIVPLTVLSSELPILGKGLPQQELV-TLISILPLLSGGLRP 245

Query: 249 IAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSVGGIMTAYTSEKAS 308
           I G++ D LG +     + L  +LT   I +      +   LV ++ G ++T Y +   S
Sbjct: 246 IFGYIADRLGILRT--TFLLTIVLTLGSISLLLGEIALSTILVGFAGGSLITLYFN--VS 301

Query: 309 RENLGVVMGFVNM-VGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVIIGL 363
            E  G     VN  + + G  +G  ++G +I  L Y+++L +  + Y +S  +IG+
Sbjct: 302 TEIFGFKFSTVNSGILYTGKALGG-VLGSIIFALLYTISLRTSEI-YTLSCSLIGV 355


>sp|P13924|TCR_STRAG TETRACYCLINE RESISTANCE PROTEIN >gi|581578|emb|CAA33712.1| (X15669)
           tetL protein (AA 1-458) [Streptococcus agalactiae]
           Length = 458
           
 Score = 69.9 bits (168), Expect = 5e-11
 Identities = 85/369 (23%), Positives = 161/369 (43%), Gaps = 41/369 (11%)

Query: 6   ILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGD 65
           ILI + +   F+  + M +    P I  D     A    + T+ +L +S+     G + D
Sbjct: 15  ILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSD 74

Query: 66  KIGRKKLLTISILGYSLSSALIVLTRDYWDL-VTVRALYGFFAGLYYAPATALISELF-R 123
           ++G K+LL   I+     S +  +   ++ L +  R + G  A  + A    +++    +
Sbjct: 75  QLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPK 134

Query: 124 ERKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKGEP 183
           E +G A G      A+G G+ P IV  +A  + W Y  L+L  M +I+ +  ++ +  + 
Sbjct: 135 ENRGKAFGLIGSIVAMGEGVGPAIVGMIAHYIHWSY--LLLIPMITIITVPFLMKLLKKE 192

Query: 184 IKVEGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYLVSRGVGMEKASLMFSMLSLVG 243
           ++++G  F I +G+ L+S      +G  F ML F  SY +S         L+ S+LS + 
Sbjct: 193 VRIKG-HFDI-KGIILMS------VGIVFFML-FTTSYSIS--------FLIVSVLSFL- 234

Query: 244 ILGSIIAGFLYDHLGKVS-VLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSVGGI--MT 300
                       H+ KV+   +   L   + F++ V+         G++  +V G   M 
Sbjct: 235 --------IFVKHIRKVTDPFVDPGLGKNILFMIGVLCG-------GIIFGTVAGFVSMV 279

Query: 301 AYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVI 360
            Y  +   + +   +   +   G     I  YI G L+DR G  L +L++ + +L  + +
Sbjct: 280 PYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRG-PLYVLNIGVTFLSVSFL 338

Query: 361 IGLDLRKTS 369
               L +T+
Sbjct: 339 TAFFLLETT 347


>pir||T37042 probable nitrate/nitrite transport protein - Streptomyces
           coelicolor >gi|5777686|emb|CAB53437.1| (AL109989)
           putative nitrate/nitrite transporter protein
           [Streptomyces coelicolor A3(2)]
           Length = 412
           
 Score = 69.9 bits (168), Expect = 5e-11
 Identities = 92/383 (24%), Positives = 163/383 (42%), Gaps = 39/383 (10%)

Query: 5   IILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIG 64
           ++L L +LG+  N+     +  L P     L +++ +  LL+   ++  SL ++P G + 
Sbjct: 22  LMLALATLGFALNFWAWALLSPLGPRFKDSLDLSSFQQSLLVAVPVVVGSLGRIPVGALT 81

Query: 65  DKIGRKKLLTISILGYSLSSALIVLTRDYWDL-----VTVRALYGFFAGL---YYAPATA 116
           D+ G + +       + L SA  ++   Y  L     +T   + GF  G+    +A    
Sbjct: 82  DRFGGRVM-------FPLVSAATIVPVLYLGLAGHSSLTALLVGGFLLGIGGTAFAVGVP 134

Query: 117 LISELF-RERKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLS---IMSSIVG 172
             S  F  ER+G A+G F  G   G+ I+ L  V +         FLV +    + ++V 
Sbjct: 135 FTSAWFPPERRGLAIGIFGAGMG-GTAISALTTVKLVDAYGMANPFLVTAAVLAVYAVVA 193

Query: 173 ILLMVAIKGEPIKVEGVKFKIPRGVFL-----LSLANFLGLGAFFAMLTFLVSYLVSRGV 227
            LL+    G  +  E +  ++     L      S    +  G + A   +L +YL   G 
Sbjct: 194 ALLLRDAPGRTVPAESLGHRMAATCKLGITWQASALYAVAFGGYVAFSVYLPTYL-KTGY 252

Query: 228 GMEKASLMFSMLS--LVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFL 285
           G+ +A     M    L+ +    + G+L D LG V V LA +L  +L   +   P+P  L
Sbjct: 253 GLTQADAANRMAGFVLLAVAMRPMGGWLSDRLGPVKV-LAGSLAVVLAGALAQSPTPA-L 310

Query: 286 IPLGLVLY--------SVGGIMTAYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFL 337
           +P+G + +        +  G + A  +  +    +G V G V   G  G  + P ++G L
Sbjct: 311 MPVGTIAFLAMAAALGAGSGAVFALVAFLSPANKVGSVTGMVGAAGGLGGFLPPLVMGTL 370

Query: 338 IDRLGYSLALLSVPLAYLVSAVI 360
               G S A+  + LA + +A +
Sbjct: 371 YGSFG-SYAIGLILLAAVAAAAL 392


>pir||B81080 drug resistance translocase family protein NMB1461 [imported] -
           Neisseria meningitidis (group B strain MD58)
           >gi|7226703|gb|AAF41820.1| (AE002496) drug resistance
           translocase family protein [Neisseria meningitidis MC58]
           Length = 461
           
 Score = 69.5 bits (167), Expect = 6e-11
 Identities = 96/350 (27%), Positives = 152/350 (43%), Gaps = 35/350 (10%)

Query: 38  NNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLV 97
           N   +GL M    L  +L+Q+P G   DK GRKK +   ++ ++  S L         LV
Sbjct: 52  NKTLVGLAMGIYGLTQALLQLPLGIASDKFGRKKTIYAGLVVFAAGSFLAAAADTLPMLV 111

Query: 98  TVRALYGFFAGLYYAPATALISELFRERKGSALGFFMVGPAIGSGIT-PLIVVPV-ALTL 155
             RA+ G  AG   A  TAL+++L R+   +     M+G +IG   +  L+V PV A  +
Sbjct: 112 AARAIQG--AGAVSAAVTALLADLTRDGVRTR-AMAMIGLSIGLTFSVSLVVAPVIADAV 168

Query: 156 SWRYAFLVLSIMSSI-VGILLMVAIKGEPIKVE----------GVKFKIPR------GVF 198
             R  F++  I++ I +G++  +    E  K+           G   K  R      G+F
Sbjct: 169 GVRGLFMLTGILTVISIGVVAWMTPDPEVSKLHEDTQAQPSRIGEVLKNRRLLTLDFGIF 228

Query: 199 LLSLANFLGLGAFFAMLTFLVSYLVSRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLG 258
            L  A      A F  L F ++ L    +   K  L  ++  LV ++  II G   + L 
Sbjct: 229 ALHAAQM----ALFTALPFAMTQLGLEKIQHWKVYLPSTITGLVVMVPLIIVGETRNKLK 284

Query: 259 KVSVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSVG-----GIMTAYTSEKASRENLG 313
           +V VL    + +    L+  + S + LI   LV+Y +G       + +  S+ A  +  G
Sbjct: 285 QVFVLGIVCIAAAQLGLLSGMRS-VGLITAYLVVYFIGFNVLEASLPSMVSKIAPSDLKG 343

Query: 314 VVMGFVNMVGFFGATIGPYIVGFLIDRLGYS--LALLSV-PLAYLVSAVI 360
             MG  N +   G   G    G L  + G+S   A  S+  L +LV AV+
Sbjct: 344 TAMGVYNTMQSLGLFAGGAAGGLLFQKYGFSGVFAFCSILMLLWLVIAVL 393


>pir||G83322 hypothetical protein PA2589 [imported] - Pseudomonas aeruginosa
           (strain PAO1) >gi|9948652|gb|AAG05977.1|AE004687_6
           (AE004687) hypothetical protein [Pseudomonas aeruginosa]
           Length = 404
           
 Score = 69.5 bits (167), Expect = 6e-11
 Identities = 86/348 (24%), Positives = 143/348 (40%), Gaps = 31/348 (8%)

Query: 38  NNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLV 97
           + AE+ LL+T   L  ++     G++ D+ G ++ +       SL    +      W L 
Sbjct: 47  DRAEVSLLVTLFGLAVAITSPLKGWLIDRWGARRTMLGLTAALSLPLLGLAAVNAVWQLY 106

Query: 98  TVRALYGFFAGLYYAPATALISELFRERKGSALGFFMVGPAIGSGITPLIVVPVALTLSW 157
            +  L G  A     P   ++   FR+R G A G   +G  +G  +  L+         W
Sbjct: 107 ALFLLIGLLAP-GNLPYGRILGLWFRQRLGVAYGLLGLGFGVGGPLGLLVGHQSLEAWGW 165

Query: 158 RYAFLVLSIMSSIVGILLMVAIKGEPIKVEGVKFKIP----------------RGVFLLS 201
           R AFLV  ++   + + L+  +  EP    GV                        F L 
Sbjct: 166 RGAFLVYGVLELGLALPLLAWLFREPAPDAGVAAGTAVAETALSGSTAPQAWRSASFWLV 225

Query: 202 LAN-FLGLGAFFAMLTFLVSYLVSRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKV 260
           L N  L +     ++T  V  LV RG+   +A    S L +  +L   + G+L D +   
Sbjct: 226 LGNQVLAVFVMSGIMTHGVPMLVERGLSRGEAGTALSALWVGMMLSQPLMGWLLDRVATP 285

Query: 261 SVLLAYALNSLL---TFLVIVIPSPLFLIPLGLVLYSVGGIMTAYTSEKA-----SRENL 312
            V L +AL ++L    FLV   PS L+   L + L  +GG   + T++          + 
Sbjct: 286 RVALPFALAAVLGMAWFLVGDTPSGLW---LAVFLVGLGGGGESGTTKYLLMRYFGLRSF 342

Query: 313 GVVMGFVNMVGF-FGATIGPYIVGFLIDRL-GYSLALLSVPLAYLVSA 358
           GV+ G +    F    ++G Y++G+L DR  GY  A   +  A+ ++A
Sbjct: 343 GVIYGSIQPFTFALSISLGAYLLGWLYDRAEGYGTAEWVLLAAFSLAA 390


>pir||F82177 probable multidrug resistance protein VC1618 [imported] - Vibrio
           cholerae (group O1 strain N16961)
           >gi|9656131|gb|AAF94772.1| (AE004239) multidrug
           resistance protein, putative [Vibrio cholerae]
           Length = 405
           
 Score = 69.1 bits (166), Expect = 8e-11
 Identities = 85/373 (22%), Positives = 159/373 (41%), Gaps = 40/373 (10%)

Query: 4   LIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYI 63
           L +   ++ G    + +      + P +     ++  +I  L  +  L  SL  VP    
Sbjct: 10  LKVTFALAFGSFLVFCNLYLFQPMLPYLANHFAVSETQINWLFAASTLALSLCLVPWAVT 69

Query: 64  GDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATA-LISELF 122
            + +GR+ ++   +    +    ++    +W LV  RAL G     + + A A ++ EL 
Sbjct: 70  SEAVGRRLVMLTGLFAMPVIGLAMLYAEQFWFLVLTRALMGVALAAFASVAVAYMVEELS 129

Query: 123 RERKGSALGFFMVGPAIGSGITPLIVVPVAL-TLSWRYAFLVLSIMSSIVGILLMVAIKG 181
            +  G A+G ++   ++G GIT  I   +    L W++A + ++I  +++G LL+  +  
Sbjct: 130 PQAFGKAIGGYIAANSLG-GITGRIAGGLLTDALGWQHAVVAMAIF-TLLGALLVAYLL- 186

Query: 182 EPIKVEGVKFKIPRGVFL--------------LSLANFLGLGAFFAMLTFLVSYLVSRGV 227
            PI+     FK  RG+F               L LA  +G G  FA+   L S +  R V
Sbjct: 187 -PIQQH---FKPQRGLFFHHNRALVKHLQNRTLWLAMLIG-GVNFALFVNLYSVMGFRLV 241

Query: 228 GMEKASLMFSMLSLV------GILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPS 281
             E  SL   + SL+      G L S +          +  ++  AL S+   L+ +I +
Sbjct: 242 A-EPYSLPIGIASLIFVCYLAGTLSSKLTANWNRRFSAIPGMMLGALISMAGMLIALIEA 300

Query: 282 -PLFLIPLGLVLYSVGGIMT-----AYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVG 335
            P  L+  GL+L S G   T     A+ S+KA++        ++ +  + G ++G + + 
Sbjct: 301 IPAMLV--GLILISFGAFFTHTLAYAWVSQKATQAKATATALYL-VHYYIGGSLGGFYLL 357

Query: 336 FLIDRLGYSLALL 348
           +     G+ +  L
Sbjct: 358 YCWQHGGWEMVTL 370


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.329    0.147    0.421 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 122815260
Number of Sequences: 2977
Number of extensions: 5051200
Number of successful extensions: 21687
Number of sequences better than 1.0e-10: 105
Number of HSP's better than  0.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 102
Number of HSP's that attempted gapping in prelim test: 21444
Number of HSP's gapped (non-prelim): 153
length of query: 372
length of database: 189,106,746
effective HSP length: 54
effective length of query: 318
effective length of database: 156,788,448
effective search space: 49858726464
effective search space used: 49858726464
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (21.7 bits)
S2: 166 (69.1 bits)