BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0761 (PAB0761) DE:TRANSPORT PROTEIN, permease
(372 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||D75094 transport protein, permease PAB0761 - Pyrococcus aby... 715 0.0
pir||H71070 hypothetical protein PH1260 - Pyrococcus horikoshii ... 618 e-176
sp|O34456|EXUT_BACSU HEXURONATE TRANSPORTER >gi|7428807|pir||A69... 130 3e-29
pir||D71144 hypothetical protein PH0367 - Pyrococcus horikoshii ... 116 5e-25
gb|AAG28456.1|AF195244_3 (AF195244) putative transporter [Pyroco... 111 1e-23
gb|AAD46810.1|AF157643_4 (AF157643) putative transporter protein... 107 2e-22
gb|AAK41360.1| Transport membrane protein (permease) [Sulfolobus... 106 6e-22
emb|CAC12461.1| (AL445067) transport membrane protein (permease)... 104 2e-21
pir||A83133 probable MFS transporter PA4096 [imported] - Pseudom... 104 2e-21
gb|AAG20513.1| (AE005123) D-lactate dehydrogenase; Dld [Halobact... 104 2e-21
pir||T44249 transport protein homolog [imported] - Arthrobacter ... 104 2e-21
gi|11498512 conserved hypothetical protein [Archaeoglobus fulgid... 101 1e-20
pir||D71112 hypothetical protein PH0667 - Pyrococcus horikoshii ... 99 1e-19
sp|P31457|DGOT_ECOLI D-GALACTONATE TRANSPORTER 95 1e-18
pir||D65171 hypothetical 48.8 kD protein in ibpA-gyrB intergenic... 95 1e-18
gb|AAD10060.1| (AF113952) multidrug-efflux transporter [Campylob... 95 1e-18
pir||D81282 probable efflux protein Cj1375 [imported] - Campylob... 95 1e-18
pir||E75048 multidrug resistance protein PAB0913 - Pyrococcus ab... 94 2e-18
pir||D83160 nitrite extrusion protein 1 PA3877 [imported] - Pseu... 90 3e-17
pir||F83064 probable MFS transporter PA4654 [imported] - Pseudom... 90 5e-17
pir||S74046 probable sugar transport protein c0110 - Sulfolobus ... 90 5e-17
gb|AAK42313.1| Sugar transport related protein [Sulfolobus solfa... 90 5e-17
pir||A83383 probable MFS transporter PA2114 [imported] - Pseudom... 89 6e-17
pir||F71713 glycerol-3-phosphate transporter (glpT) RP054 - Rick... 88 2e-16
pir||T46710 multidrug resistance transporter [imported] - Lister... 87 2e-16
pir||G71118 hypothetical protein PH0718 - Pyrococcus horikoshii ... 87 2e-16
sp|P94131|MUCK_ACICA CIS,CIS-MUCONATE TRANSPORT PROTEIN >gi|1842... 86 6e-16
pir||E75042 transporter (major facilitator family) related PAB08... 86 7e-16
pir||S56504 hypothetical 46.6K protein (leuX-fecE intergenic reg... 85 1e-15
sp|P39352|YJHB_ECOLI HYPOTHETICAL METABOLITE TRANSPORT PROTEIN I... 85 1e-15
pir||D83518 cis,cis-muconate transporter MucK PA1019 [imported] ... 85 2e-15
gi|11497979 oxalate/formate antiporter (oxlT-2) [Archaeoglobus f... 85 2e-15
dbj|BAB05122.1| (AP001511) multidrug resistance protein [Bacillu... 85 2e-15
sp|P27669|UHPC_SALTY REGULATORY PROTEIN UHPC >gi|421217|pir||C41... 84 2e-15
gb|AAB48105.1| (U41818) PhlE [Pseudomonas fluorescens] 84 3e-15
pir||G64494 quinolone resistance protein norA homolog - Methanoc... 84 3e-15
sp|O51798|MMLH_ALCEU PROBABLE 4-METHYLMUCONOLACTONE TRANSPORTER ... 84 3e-15
sp|P39637|YWFA_BACSU HYPOTHETICAL 44.5 KD PROTEIN IN ROCC-PTA IN... 83 5e-15
sp|P42609|EXUT_ECOLI HEXURONATE TRANSPORTER >gi|7428805|pir||B65... 83 6e-15
sp|P42613|GARP_ECOLI PROBABLE GALACTARATE TRANSPORTER (D-GALACTA... 83 6e-15
gb|AAA57897.1| (U18997) ORF_o472 [Escherichia coli] 82 8e-15
pir||B83017 probable MFS transporter PA5030 [imported] - Pseudom... 81 2e-14
gi|11498923 multidrug resistance protein [Archaeoglobus fulgidus... 80 3e-14
pir||T47026 hypothetical protein [imported] - Yersinia pestis >g... 80 3e-14
sp|P39398|YJJL_ECOLI HYPOTHETICAL 49.4 KD PROTEIN IN TSR-MDOB IN... 80 3e-14
pir||D75358 probable fosmidomycin resistance protein - Deinococc... 80 4e-14
pir||D72302 hypothetical protein TM1021 - Thermotoga maritima (s... 80 5e-14
gb|AAF58060.1| (AE003808) CG8428 gene product [Drosophila melano... 80 5e-14
gb|AAK41596.1| Transport membrane protein (permease) [Sulfolobus... 79 7e-14
sp|P37948|GLPT_BACSU GLYCEROL-3-PHOSPHATE TRANSPORTER (G-3-P TRA... 78 1e-13
sp|P46907|NARK_BACSU NITRITE EXTRUSION PROTEIN (NITRITE FACILITA... 78 1e-13
dbj|BAB13277.1| (AP001119) hypothetical protein [Buchnera sp. APS] 78 2e-13
gb|AAA16158.1| (M80252) norA1199 protein [Staphylococcus aureus]... 78 2e-13
sp|Q46916|GUDP_ECOLI PROBABLE GLUCARATE TRANSPORTER (D-GLUCARATE... 78 2e-13
pir||A64668 chloramphenicol resistance protein homolog HP1185 - ... 77 3e-13
emb|CAC13963.1| (AJ012115) multidrug efflux transporter [Listeri... 77 3e-13
gb|AAG34371.1|AF197465_3 (AF197465) putative nitrate/nitrite tra... 77 3e-13
dbj|BAA36484.1| (AB019536) NorA [Staphylococcus aureus] 77 4e-13
emb|CAB76354.1| (AL158061) putative transmembrane transport prot... 77 4e-13
gb|AAK42961.1| Proline/betaine transporter, putative [Sulfolobus... 76 5e-13
gi|11498744 multidrug resistance protein [Archaeoglobus fulgidus... 76 5e-13
emb|CAA07482.1| (AJ007367) multi-drug resistance efflux pump [St... 76 5e-13
emb|CAB61680.1| (AL133213) putative transmembrane transport prot... 76 5e-13
pir||F69814 fosmidmycin resistance protein homolog yfnC - Bacill... 76 6e-13
gb|AAB31949.1| (S74031) NorA {ISP794, quinolone resistance} [Sta... 76 6e-13
sp|P21191|NORA_STAAU QUINOLONE RESISTANCE NORA PROTEIN >gi|97835... 76 8e-13
pir||D83117 probable MFS transporter PA4233 [imported] - Pseudom... 76 8e-13
pir||B82991 glycerol-3-phosphate transporter PA5235 [imported] -... 76 8e-13
sp|P42237|GUDP_BACSU PROBABLE GLUCARATE TRANSPORTER (D-GLUCARATE... 75 2e-12
pir||F83233 probable MFS transporter PA3303 [imported] - Pseudom... 75 2e-12
pir||H71846 hypothetical protein jhp1111 - Helicobacter pylori (... 74 2e-12
gb|AAG23889.1| (AY008833) TcaB [Staphylococcus aureus] 74 2e-12
gb|AAK42828.1| Permease [Sulfolobus solfataricus] 73 4e-12
sp|O34691|YCEI_BACSU HYPOTHETICAL METABOLITE TRANSPORT PROTEIN I... 73 4e-12
sp|Q43975|PCAK_ACICA 4-HYDROXYBENZOATE TRANSPORTER >gi|3172116|g... 73 4e-12
pir||S56583 hypothetical protein f261b - Escherichia coli >gi|53... 73 5e-12
pir||E69783 bicyclomycin resistance protein homolog ydgK - Bacil... 73 5e-12
dbj|BAB04893.1| (AP001511) multidrug-efflux transporter [Bacillu... 73 5e-12
gb|AAK41760.1| Transport protein [Sulfolobus solfataricus] 73 7e-12
gb|AAC45758.1| (U40014) nitrate transporter [Staphylococcus carn... 73 7e-12
gi|11499136 conserved hypothetical protein [Archaeoglobus fulgid... 72 1e-11
pir||E83385 hypothetical protein PA2091 [imported] - Pseudomonas... 72 1e-11
dbj|BAB06030.1| (AP001515) unknown conserved protein [Bacillus h... 72 1e-11
emb|CAC08554.1| (AL121673) bA305P22.2 (novel protein) [Homo sapi... 72 1e-11
sp|P44535|YDEA_HAEIN HYPOTHETICAL PROTEIN HI0135 >gi|1074278|pir... 71 2e-11
gb|AAC15508.1| (L49465) hypothetical metabolite transport protei... 71 2e-11
pir||F71848 probable transporter - Helicobacter pylori (strain J... 71 2e-11
pir||B83180 probable MFS transporter PA3718 [imported] - Pseudom... 71 2e-11
dbj|BAB07028.1| (AP001518) multidrug resistance protein [Bacillu... 71 2e-11
gb|AAB81315.1| (U89712) putative 3-(3-hydroxyphenyl) propionate ... 71 2e-11
pir||E64667 multidrug-efflux transporter - Helicobacter pylori (... 71 2e-11
emb|CAB93456.1| (AL357591) putative integral membrane transport ... 71 2e-11
emb|CAB71269.1| (AL138598) putative integral membrane efflux pro... 71 3e-11
pir||E81862 probable integral membrane transporter NMA1673 [impo... 71 3e-11
gb|AAG19033.1| (AE005003) multidrug resistance protein homolog; ... 71 3e-11
sp|Q51955|PCAK_PSEPU 4-HYDROXYBENZOATE TRANSPORTER >gi|1147822|g... 70 4e-11
gb|AAK42225.1| Metabolite transport protein [Sulfolobus solfatar... 70 4e-11
pir||S74875 quinolone resistance protein norA - Synechocystis sp... 70 4e-11
gb|AAB70881.1| (U86689) exuT [Pectobacterium chrysanthemi] 70 4e-11
gb|AAK41393.1| Transport protein, permease [Sulfolobus solfatari... 70 5e-11
sp|P13924|TCR_STRAG TETRACYCLINE RESISTANCE PROTEIN >gi|581578|e... 70 5e-11
pir||T37042 probable nitrate/nitrite transport protein - Strepto... 70 5e-11
pir||B81080 drug resistance translocase family protein NMB1461 [... 69 6e-11
pir||G83322 hypothetical protein PA2589 [imported] - Pseudomonas... 69 6e-11
pir||F82177 probable multidrug resistance protein VC1618 [import... 69 8e-11
>pir||D75094 transport protein, permease PAB0761 - Pyrococcus abyssi (strain
Orsay) >gi|5458569|emb|CAB50057.1| (AJ248286) TRANSPORT
PROTEIN, permease [Pyrococcus abyssi]
Length = 372
Score = 715 bits (1826), Expect = 0.0
Identities = 372/372 (100%), Positives = 372/372 (100%)
Query: 1 MEKLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPA 60
MEKLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPA
Sbjct: 1 MEKLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPA 60
Query: 61 GYIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISE 120
GYIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISE
Sbjct: 61 GYIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISE 120
Query: 121 LFRERKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIK 180
LFRERKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIK
Sbjct: 121 LFRERKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIK 180
Query: 181 GEPIKVEGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYLVSRGVGMEKASLMFSMLS 240
GEPIKVEGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYLVSRGVGMEKASLMFSMLS
Sbjct: 181 GEPIKVEGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYLVSRGVGMEKASLMFSMLS 240
Query: 241 LVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSVGGIMT 300
LVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSVGGIMT
Sbjct: 241 LVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSVGGIMT 300
Query: 301 AYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVI 360
AYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVI
Sbjct: 301 AYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVI 360
Query: 361 IGLDLRKTSYKG 372
IGLDLRKTSYKG
Sbjct: 361 IGLDLRKTSYKG 372
>pir||H71070 hypothetical protein PH1260 - Pyrococcus horikoshii
>gi|3257679|dbj|BAA30362.1| (AP000005) 372aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 372
Score = 618 bits (1577), Expect = e-176
Identities = 307/371 (82%), Positives = 346/371 (92%)
Query: 1 MEKLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPA 60
M+KLIILILISLGWIFNYSHRMAVPSLAPI+MK+L INN E+GLLMT+LLLPYSLIQVPA
Sbjct: 1 MQKLIILILISLGWIFNYSHRMAVPSLAPILMKELSINNTEVGLLMTALLLPYSLIQVPA 60
Query: 61 GYIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISE 120
GYIGDKIGRKKLLT+SILGYS+SSALIVL R+YWDLV +RALYGFFAGLYYAPAT+LISE
Sbjct: 61 GYIGDKIGRKKLLTLSILGYSISSALIVLARNYWDLVAIRALYGFFAGLYYAPATSLISE 120
Query: 121 LFRERKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIK 180
LFRE+KGSALGFFM+GPAIGSGITPLIVVPVAL L+WR +FLVLSIMSSIVG+LL++ +K
Sbjct: 121 LFREKKGSALGFFMIGPAIGSGITPLIVVPVALMLNWRLSFLVLSIMSSIVGVLLVLTVK 180
Query: 181 GEPIKVEGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYLVSRGVGMEKASLMFSMLS 240
GEP++VE KF IP+GV LLSLANFLGLGAFFAMLTFLVSYLVS+GV +++ASLMFS+LS
Sbjct: 181 GEPVEVERAKFSIPKGVLLLSLANFLGLGAFFAMLTFLVSYLVSKGVDIKEASLMFSILS 240
Query: 241 LVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSVGGIMT 300
LVG+ GS+ AGFLYD+ GKVSV LAY LN LLTFL+IV P+PL LIPLGLVLYSVGGI+T
Sbjct: 241 LVGVFGSVTAGFLYDYAGKVSVFLAYLLNFLLTFLIIVFPTPLLLIPLGLVLYSVGGIIT 300
Query: 301 AYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVI 360
AYT+EKA + NLGVVMGFVNMVGFFGAT GPY+VGFLID+LGYS ALLSVPLAYLVSA+I
Sbjct: 301 AYTAEKAEKSNLGVVMGFVNMVGFFGATTGPYVVGFLIDKLGYSRALLSVPLAYLVSALI 360
Query: 361 IGLDLRKTSYK 371
I +D+RKTSYK
Sbjct: 361 IIVDIRKTSYK 371
>sp|O34456|EXUT_BACSU HEXURONATE TRANSPORTER >gi|7428807|pir||A69853 hexuronate
transporter homolog yjmG - Bacillus subtilis
>gi|2612908|gb|AAC46332.1| (AF015825) hexuronate
transporter-like protein [Bacillus subtilis]
>gi|2633590|emb|CAB13093.1| (Z99110) similar to
hexuronate transporter [Bacillus subtilis]
Length = 422
Score = 130 bits (323), Expect = 3e-29
Identities = 104/397 (26%), Positives = 183/397 (45%), Gaps = 37/397 (9%)
Query: 2 EKLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAG 61
+KL +++ + L + NY R A+ AP I DL ++ ++GL+ +S + Y++ G
Sbjct: 5 DKLPVILFLFLAGVINYLDRSALSIAAPFIQDDLTLSATQMGLIFSSFSIGYAIFNFLGG 64
Query: 62 YIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISEL 121
D+ G K L ++++ +SL S + L + L+ +R L+G G A +++
Sbjct: 65 VASDRYGAKLTLFVAMVVWSLFSGAVALAFGFVSLLIIRILFGMGEGPLSATINKMVNNW 124
Query: 122 F-RERKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIK 180
F ++ S +G G +G I+ IV +A+ SW+ +F+++ I+ I +L +K
Sbjct: 125 FPPTQRASVIGVTNSGTPLGGAISGPIVGMIAVAFSWKVSFVLIMIIGLIWAVLWFKFVK 184
Query: 181 GEP---------IKVE-GVKFKIPRGVFLLSLANFLGLGAFFA-------MLTFLVSYLV 223
+P IK E KIP +L AFFA LT+ SYLV
Sbjct: 185 EKPQETIKEAPAIKAETSPGEKIPLTFYLKQKTVLFTAFAFFAYNYILFFFLTWFPSYLV 244
Query: 224 -SRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSP 282
RG+ +E S++ + ++G +G GF+ D++ K + + + + + S
Sbjct: 245 DERGLSVESMSVITVIPWILGFIGLAAGGFVSDYVYKKTARKGVLFSRKVVLVTCLFSSA 304
Query: 283 LFLIPLGLV----------------LYSVGGIMTAYTSEKASRENLGVVMGFVNMVGFFG 326
+ + GLV LY G I A + + N+G V GF++ +
Sbjct: 305 VLIGFAGLVATTAGAVTLVALSVFFLYLTGAIYWAVIQDVVDQNNVGSVGGFMHFLANTA 364
Query: 327 ATIGPYIVGFLIDRLG-YSLA-LLSVPLAYLVSAVII 361
IGP + GF++D+ G +S A LL+ LA S +I
Sbjct: 365 GIIGPALTGFIVDQTGTFSGAFLLAGGLAVFASLAVI 401
>pir||D71144 hypothetical protein PH0367 - Pyrococcus horikoshii
>gi|3256758|dbj|BAA29441.1| (AP000002) 457aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 457
Score = 116 bits (287), Expect = 5e-25
Identities = 105/402 (26%), Positives = 181/402 (44%), Gaps = 54/402 (13%)
Query: 5 IILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIG 64
I +IL+ L F + + +P IMK+ GI ++G + + + +LI + G +
Sbjct: 21 ISIILLVLMATFLMADQNLLPPNYQQIMKEFGIGETQMGFVSSIFVATSALITIIWGMLA 80
Query: 65 DKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRE 124
D RKKLL I +L + L YW L+T+R L G G +LI+++F E
Sbjct: 81 DIKQRKKLLVIGVLLGEIPCFLTAYVHSYWQLLTMRFLTGIGIGSIIPIGYSLIADMFEE 140
Query: 125 RKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKGEPI 184
K G+ + A G G +++ +T SWR F++ ++ + I+ L + I EP
Sbjct: 141 EK-RGRGYSYIETAFGFGTLFGMIIAGVIT-SWRTPFIIAAVPNFILAPLFYI-IAEEPR 197
Query: 185 KVEG---VKFKIPRGV--------------------FLLSLANFLGLGAFFAMLTFLVSY 221
+ EG ++ I +G L+ L +G + ++ +L+S+
Sbjct: 198 RGEGEREIRVLIEKGYEYAYKLSLEAVKKSLKTRTNILIFLQGIIGTVPWGILMYWLISF 257
Query: 222 L-VSRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIP 280
L V+RG+ + A+ M ++ + +LGS+ GF+ D+ + + FL ++
Sbjct: 258 LQVTRGMDKQTATFMLLIIGIASVLGSLFGGFVGDYFETRKRGGRAVITGIAIFLGMIAA 317
Query: 281 SPLFLIP----------LGLVLYSV---------GGIMTAYTSEKASRENLGVVMGFVNM 321
L L P LGL +YS+ G + A S+ E+ G V G N+
Sbjct: 318 IGLILYPLPSKLNTIHWLGLTVYSILFIQFVSYAGPNVRAIVSQVNLPEDRGTVFGLFNI 377
Query: 322 VGFFGATIGPYIVGFLID---RLGYSLALLSVPLAYLVSAVI 360
+ G IGP + GFLI+ ++GY + PLAY + +I
Sbjct: 378 LDNVGKAIGPVLGGFLIETLVQMGY-----TKPLAYQYTLLI 414
>gb|AAG28456.1|AF195244_3 (AF195244) putative transporter [Pyrococcus furiosus]
Length = 443
Score = 111 bits (275), Expect = 1e-23
Identities = 104/403 (25%), Positives = 185/403 (45%), Gaps = 48/403 (11%)
Query: 1 MEKLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPA 60
+ + + ++L+ L F + + +P IMK+ GI ++GL+ + + +LI +
Sbjct: 4 IRRRVSIVLLILMAAFLMADQNLLPPNYQQIMKEFGIGETQMGLVSSIFVATSALITIIW 63
Query: 61 GYIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISE 120
G + D RKKLL I +L + L + YW L+ +R L G G +LI++
Sbjct: 64 GMLADIKQRKKLLVIGVLLGEIPCFLTAYVQTYWQLLAMRFLTGIGIGSIIPIGYSLIAD 123
Query: 121 LFRERKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIK 180
+F E K G+ + A G G T ++ + SWR F++ ++ + I+ L + I
Sbjct: 124 MFEEEK-RGRGYSYIETAFGFG-TLFGMIIAGMIASWRTPFIIAAVPNFILAPLFYI-IA 180
Query: 181 GEPIKVEG---VKFKIPRGV--------------------FLLSLANFLGLGAFFAMLTF 217
EP + G ++ I +G L+ L +G + +L +
Sbjct: 181 EEPKRGAGEKEIRALIEKGYEYTYRLNLEAIRKSFQTKTNILIFLQGIIGTVPWGILLYW 240
Query: 218 LVSYL-VSRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHL------GKVSVL-LAYALN 269
LVS+L V+RG+ A+ + ++ + + GS++ GF+ D+ G+ ++ +A L
Sbjct: 241 LVSFLQVTRGMDKSTATFVLLIIGIASVFGSLLGGFVGDYFEAKRRGGRATITGIAIFLG 300
Query: 270 SLLTFLVIVIPSPLFLIP---LGLVLYSV---------GGIMTAYTSEKASRENLGVVMG 317
L + +I+ P P L +GL +YS+ G + A S+ E+ G V G
Sbjct: 301 MLASIGLILYPLPSKLSTVHWIGLAIYSILFIQFVSYAGPNVRAIVSQVNLPEDRGTVFG 360
Query: 318 FVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVI 360
N++ G IGP GFLI+ L S+ + PLAY + +I
Sbjct: 361 LFNILDNVGKAIGPLFGGFLIETL-KSMGYME-PLAYQYTLLI 401
>gb|AAD46810.1|AF157643_4 (AF157643) putative transporter protein [Mycobacterium smegmatis]
Length = 413
Score = 107 bits (265), Expect = 2e-22
Identities = 105/412 (25%), Positives = 189/412 (45%), Gaps = 55/412 (13%)
Query: 5 IILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIG 64
++L+L+++ NY R ++ P I +D I+ GLL+++ Y+ +Q+PAG++
Sbjct: 4 LLLLLVTV----NYVDRGSLSVALPAIKEDFHISAEVTGLLLSAFFWAYAAMQIPAGWLI 59
Query: 65 DKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELF-- 122
D+ G +KL+T + G+ ++AL + + + R L G PA ++ +F
Sbjct: 60 DRFGPRKLITAACTGWGTATALSGMAPNIGTMAVARGLIG-VTEAPIMPAGGKLNAVFLT 118
Query: 123 RERKGSALGFFMVGPAIGSGITPL-IVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKG 181
+ +G G +GS + + + T SWR+AF++ ++ ++GI AI+
Sbjct: 119 EKERGRGATILDAGAPLGSAVGGIAFAALIGATGSWRWAFIIAGAVTVLLGIWAWRAIRD 178
Query: 182 EP---IKVE-------------------------GVKFKIPRGVFLLSLANFLGL-GAFF 212
P KV+ G+ + + F A +LG G F+
Sbjct: 179 TPEEHPKVDEAEREYLVSAHREESARHQSTGERAGLVYYMKYRSFWAMCAGWLGFNGVFY 238
Query: 213 AMLTFLVSYLVSRGVGMEKASLMFSMLSLV--GILGSIIAGFLYDHLGKVSVLLAYALNS 270
+LT+ +L S G E ++ +S ++ G +G II G L D L + + S
Sbjct: 239 GLLTWGPLFL-SESKGFELEAIGWSTFAIFGSGFVGEIIGGQLADRLKEKGYGTNRVMRS 297
Query: 271 LLTFL----------VIVIPSPL-FLIPLGLVLYSVG--GIMTAYTSEKASRENLGVVMG 317
LL F V+++PSPL ++ L VL+ + G+ + S RE+ GV+ G
Sbjct: 298 LLGFAGMCVVAGLVGVVLMPSPLAAVLLLSTVLFFLRWVGLFWSVPSILGGREDAGVLGG 357
Query: 318 FVNMVGFFGATIGPYIVGFLIDRLG-YSLALL-SVPLAYLVSAVIIGLDLRK 367
+N+ G + P VGF++ G Y+ ALL V +++A ++ LD K
Sbjct: 358 AMNLAGNISGFVTPMAVGFIVGATGAYTWALLYFVGAGVIMTAAVLILDYSK 409
>gb|AAK41360.1| Transport membrane protein (permease) [Sulfolobus solfataricus]
Length = 378
Score = 106 bits (261), Expect = 6e-22
Identities = 85/352 (24%), Positives = 159/352 (45%), Gaps = 19/352 (5%)
Query: 6 ILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGD 65
++ L + + +Y R+ +AP+ L E ++ L Y L+Q+P+G + D
Sbjct: 6 VIFLSASSFFLSYFSRVTWSIVAPL--STLKTTTTEDSIIFALFFLGYILVQIPSGMLAD 63
Query: 66 KIGRKKLLTISILGYS----LSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISEL 121
+I LL +S+LG + +SS ++ +Y L GF AG Y L+S
Sbjct: 64 RISANHLLFLSLLGVAITSFISSTFPLIMLEY----VASFLMGFSAGWIYPITVKLLSAS 119
Query: 122 FRERK-GSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIK 180
F R A+ + + + + +I+ +ALT W ++F ++ +S I+GIL ++ +
Sbjct: 120 FDSRDLPIAMSIYSISWPLSIVASGVIIPFLALTFGWEFSFYFITALSIILGILALLYLP 179
Query: 181 GEPIKVEGVKFK---IPRGVFLLSLANFLGLGAFFAMLTFLVSYLVSRGVGMEKASLMFS 237
+ +KFK + +S+ FL ++ ++ +L YL+S A +++S
Sbjct: 180 SLKLSKSIIKFKDVVKDKNSIYISVGGFLFYLTYWILVLYLYKYLLSVVGNEYTAGIIYS 239
Query: 238 MLSLVGILGSIIAGFLYDHLGK----VSVLLAYALNSLL-TFLVIVIPSPLFLIPLGLVL 292
+L GI +I+AG++ LG +S + Y+ + LL +F VI + + LG
Sbjct: 240 FTALTGIFSTILAGYIIKSLGVKRTFLSFITLYSFSLLLFSFSKNVIVIGIDALALGFFR 299
Query: 293 YSVGGIMTAYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYS 344
+ + + + +E G V G N F +G I LI+ Y+
Sbjct: 300 FVITPTSSTAVAVIGGKERSGSVTGLANFFWQFSGIVGSIIAPLLINLFTYT 351
>emb|CAC12461.1| (AL445067) transport membrane protein (permease) related protein
[Thermoplasma acidophilum]
Length = 382
Score = 104 bits (257), Expect = 2e-21
Identities = 78/351 (22%), Positives = 168/351 (47%), Gaps = 14/351 (3%)
Query: 1 MEKLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPA 60
M KL L + S + +Y R++ L+ + A+ G + Y ++Q+P+
Sbjct: 1 MAKLYPLFVGSASFFLSYYVRLSWTILS--VYMPFKPTVAQEGFAFAIFFVGYVIVQIPS 58
Query: 61 GYIGDKIGRKKLLTISILGYSLSSALIVLTRDY-WDLVTVRALYGFFAGLYYAPATALIS 119
G+I D+ ++++S++G ++S+ + L+ D W+ V+ + G AG Y + +++
Sbjct: 59 GFISDRYSGGIVISLSLIGLAVSAIMSALSPDIEWEYVS-SLIMGLTAGWVYPASINVMN 117
Query: 120 ELFRERKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGIL---LM 176
+RE + +G++ + + ++ ++ +AL + W++ + +I S ++ I+ L
Sbjct: 118 HYYRENRSVYIGYYSIAWPLAIVLSGFMLPYLALKIGWQWGYYSSAIASIVIAIMAFSLK 177
Query: 177 VAIKGEPIKVEGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYLVSRGVGMEKASLMF 236
G I +K R V LLS FL +++++ + Y VS G+ + +F
Sbjct: 178 TEHSGYSIDPSLIK---NRDVLLLSFGGFLFFISYWSLTLYAYKYFVSIGISPVISGFVF 234
Query: 237 SMLSLVGILGSIIAGFLYDHLG-KVSVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSV 295
S +++ G+ + ++G++ +G K +V+++ ++ I + + LI + LV+
Sbjct: 235 SSMAITGLFSTSLSGYIISRIGTKNAVVISLVAYGIIILAFSFIRNAVLLIVISLVMGFF 294
Query: 296 GGIMT---AYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGY 343
I+T + S + RE G V G NM +GP + LI +G+
Sbjct: 295 RFIITPGNSGLSIEIGRERAGSVSGIANMFWQSSGIVGPIVSSALILDVGF 345
>pir||A83133 probable MFS transporter PA4096 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9950297|gb|AAG07483.1|AE004826_1
(AE004826) probable MFS transporter [Pseudomonas
aeruginosa]
Length = 419
Score = 104 bits (257), Expect = 2e-21
Identities = 99/392 (25%), Positives = 191/392 (48%), Gaps = 32/392 (8%)
Query: 5 IILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIG 64
++L ++ L + F + R+A+ L P + ++L ++N+ +G+L + L L +++ G
Sbjct: 13 VLLCVLFLTFGFVFFDRLALSFLFPFMEQELQLSNSHLGMLSSVLALAWAVSGALVGAWS 72
Query: 65 DKIG-RKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFR 123
D+ G RK LL ++++ +SL SAL L + L+ R + G G + +L+ E
Sbjct: 73 DRRGQRKPLLIVAVILFSLCSALSGLVGGFLSLLLFRGIMGLAEGPILPLSQSLMVEASS 132
Query: 124 -ERKGSALGFFMVGPA--IGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIK 180
R+G +G A +G+ I P ++V +A L WR+AF+V + ++ L+ ++
Sbjct: 133 PHRRGLNMGLLQGSAAGLLGAVIGPPLLVALAEALGWRHAFIVSLLPGLLIAWLIWRHVR 192
Query: 181 GEPIKVE----------GVKFKI--PRGVFLLSLANFLGLGAFFAMLTFLVSYLV-SRGV 227
+P + + G + + R + L +L + + + F +++F ++LV +RG
Sbjct: 193 PDPPRAQRPAPRAEEAKGKRLALLKSRNILLCTLISCVFVTWFIVLISFTPTFLVNARGF 252
Query: 228 GMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIV-IPSPLFLI 286
+ S L + ++ + D +G+ L+A++L + L ++ P+ L
Sbjct: 253 SPATMGRLMSCLGVAWVVWGFAVPAISDRIGRRPTLVAFSLLAACCPLALLYAPNATSLG 312
Query: 287 PLGLVLYSVGGIMTAY----TSEKASR----ENLGVVMGFVNMVGFFGATIGPYIVGFLI 338
L L+ Y+ G T + +E SR LG++MG +VG F + P + GF
Sbjct: 313 LLLLLTYTGLGCFTLFMATIPAETVSRGVIATALGLIMGLGELVGGF---LAPTVAGFAA 369
Query: 339 DRLGYSLAL-LSVPLAYLVSAVIIGLDLRKTS 369
DR G S+ + +S A L A + L LR+T+
Sbjct: 370 DRFGLSIVMWMSCGGALL--AAFLSLFLRETA 399
>gb|AAG20513.1| (AE005123) D-lactate dehydrogenase; Dld [Halobacterium sp. NRC-1]
Length = 353
Score = 104 bits (257), Expect = 2e-21
Identities = 95/347 (27%), Positives = 160/347 (45%), Gaps = 24/347 (6%)
Query: 34 DLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSLSSALIVLTRDY 93
D+ I N + G T+L Y+L+Q P+G + D + RK LL + S ++ R Y
Sbjct: 8 DIHITNTKAGFAFTTLWGLYALLQYPSGRLSDALSRKTLLVTGLGMASGGFVVLATARSY 67
Query: 94 WDLVTVRALYGFFAGLYYAPATALISELFRERKGSALGFFMVGPAIGSGITPLIVVPVAL 153
L+ A+ G AGLY A AL+++L+ ++G A G +G G++ + VAL
Sbjct: 68 AALLVGAAIVGTGAGLYPTAARALVADLYSTKQGRAFGLHTASGDLG-GMSAAGIAAVAL 126
Query: 154 TL-SWRYAFLVLSIMSSIVGILLMV------AIKGEPIKVEGVKFKIPRGVFLLSLANFL 206
L SWRYAF+ + +++ V I L V + + V ++ G +
Sbjct: 127 ALLSWRYAFVPIVCLTAAVAIALHVWSRESYVFERRSLAVRDTAARLLSGTQFRWILVAY 186
Query: 207 GLGAFF--AMLTFLVSYLVSRGVGMEKA----SLMFSMLSLVGILGSIIAGFLYDHLGKV 260
L AF A+ FL ++ G E A ++ F L VG + AG L D + +
Sbjct: 187 TLYAFTWQAIAAFLPTFFTD---GKEFAPVVGTVAFGALFAVGAIAKPTAGTLSDTISRR 243
Query: 261 SVLL-AYALNSLLTFLVIVIPSPLFLIPLGLVLYSVG-----GIMTAYTSEKASRENLGV 314
++ + A L + V+V+PSP+ + +V+++ G +M +Y + E+ G
Sbjct: 244 ALAVGALVLGAAALSAVVVVPSPVAAVG-AVVVFAAGLLAFPPVMQSYLMDAFPPESAGG 302
Query: 315 VMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVII 361
+G + V +GP VG + Y +A + A +V+AVII
Sbjct: 303 DLGAMRTVYIGLGALGPTYVGAVSTAANYEIAFWGLVGALIVAAVII 349
>pir||T44249 transport protein homolog [imported] - Arthrobacter sp. (strain
TE1826) >gi|3116222|dbj|BAA25927.1| (AB007122)
transporter [Arthrobacter sp.]
Length = 405
Score = 104 bits (256), Expect = 2e-21
Identities = 86/364 (23%), Positives = 166/364 (44%), Gaps = 17/364 (4%)
Query: 21 RMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGY 80
RMA L P + + L ++ ++G+L TS + Y + + AG + K G KKL+ + L
Sbjct: 26 RMAYGILMPFMKESLSLSYQQMGMLGTSTAIGYLSLVLFAGILAAKWGSKKLVVLGNLLV 85
Query: 81 SLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRERKGSALGFFMVGPAIG 140
+ + + ++ + L G A Y P ++ F R+G +GF + G +G
Sbjct: 86 AFGLLYLSWAQSFFACLAGMILLGIGAAFTYTPVVNIVVGWFPNRRGMMIGFVISGLGLG 145
Query: 141 SGITPLIVVPVALTLS---WRYAFLVLSIMSSIVGILLMVAIKGEP---IKVEGVKFKIP 194
S I ++ S WRY +LV SI++ I ++ ++ P K
Sbjct: 146 SLIASALIPFFTAWYSDNGWRYLWLVFSIIAFISAVVSYFILRDPPEVSRKTAAKSHSFL 205
Query: 195 RGVFL----LSLANFLGLGAFFAML--TFLVSYLVSRGVGMEKASLMFSMLSLVGILGSI 248
R V+L + +A GL F ++ +FL S+++ G+ A + S+ S++ I
Sbjct: 206 RDVYLNHKVILVAVIYGLIGFAYLIPQSFLFSFILDTGINSYSAGQLMSLGSIMSIFSGP 265
Query: 249 IAGFLYDHLG-KVSVLLAYALNSLLTFLVIVIPSPLFLIPL----GLVLYSVGGIMTAYT 303
+ G + D +G K+S+L+ L ++ + I P+ L + G+ + + ++ A +
Sbjct: 266 LWGAVSDKIGRKMSLLVTLLLGAVSVIIPIGFPTYLGFVICQFLWGINVVGMLSLIQALS 325
Query: 304 SEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVIIGL 363
+E+ + V +G+ + G GP + G++ID G +L + L+ A ++ L
Sbjct: 326 TEQVHQSYAPVALGYTTVYFAVGQLAGPGLGGWMIDHFGGIPPVLFLCSGLLILAFLLSL 385
Query: 364 DLRK 367
+ K
Sbjct: 386 QVNK 389
>gi|11498512 conserved hypothetical protein [Archaeoglobus fulgidus]
>gi|7483062|pir||C69363 conserved hypothetical protein
AF0907 - Archaeoglobus fulgidus
>gi|2649701|gb|AAB90333.1| (AE001041) conserved
hypothetical protein [Archaeoglobus fulgidus]
Length = 419
Score = 101 bits (250), Expect = 1e-20
Identities = 92/382 (24%), Positives = 162/382 (42%), Gaps = 34/382 (8%)
Query: 14 WIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLL 73
+ F Y HR + LA +M++ + +G+L ++ PY L+Q+P GY+ D G +
Sbjct: 31 YFFVYFHRTSSAILATTLMEEFAVTALAVGVLSSAYFYPYGLMQIPVGYLSDTKGPRLTT 90
Query: 74 TISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRERKGSAL-GF 132
T+ L + + L ++ ++ V R L G Y P L+S FR + + L G
Sbjct: 91 TVFTLLAFVGTVLFAVSPNFEVAVLGRFLIGIGVSGVYIPTIKLLSRWFRVDEFATLTGV 150
Query: 133 FMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKGEPIKV-----E 187
+G+ ++ + + WR FL + ++ ++ + + ++ P V E
Sbjct: 151 LFAVGNMGALVSAYPLATMVSLFGWRVTFLFIGAITFVLALSCWIFVRDSPGGVLEKSRE 210
Query: 188 GVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSY---------LVSRGVGMEKASLMFSM 238
G +F V +L+ +L + F ++ Y + G+ E+A + M
Sbjct: 211 GGRFATNFRVVVLNPVVWLIATSAFLRYGIVMGYQGLWGGPYLMDVYGMQREEAGGVLMM 270
Query: 239 LSLVGILGSIIAGFLYD--------HLGKVSVLLAYALNSLLTFLVIVIPSPLFLIPLGL 290
+ L ILG+ I GFL D L + + + L+ F + L+ I +
Sbjct: 271 VGLGTILGAPIIGFLSDKVFRTRKWFLVAAGIGFTFTMAPLVFFTASLTVFQLYAISFLI 330
Query: 291 VLYSVGG-IMTAYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLG------- 342
L+S G + A E E G+ VN+ FFG + +G+L+D +G
Sbjct: 331 GLFSAAGPVAYALIKESYPLEVTGLATSIVNVFPFFGGALFQVFMGYLMDTVGMVDGSYP 390
Query: 343 ---YSLALLSVPLAYLVSAVII 361
YSLA A +VSAV+I
Sbjct: 391 PEAYSLAFSFCLAASVVSAVLI 412
>pir||D71112 hypothetical protein PH0667 - Pyrococcus horikoshii
>gi|3257075|dbj|BAA29758.1| (AP000003) 413aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 413
Score = 98.7 bits (242), Expect = 1e-19
Identities = 104/387 (26%), Positives = 169/387 (42%), Gaps = 41/387 (10%)
Query: 7 LILISLGWIF-NYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGD 65
+ ++G F N + + P L + MK +G +GLL L ++ Q P GY+ D
Sbjct: 31 ITFFAIGMFFANLAWGIGYPYLT-VYMKIIGGTMFLVGLLSVIYNLTSAIFQYPFGYLSD 89
Query: 66 KIGRKK-LLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPA-TALISELFR 123
KIG++K + + +L + L++ L+++R G G +APA +ALISEL
Sbjct: 90 KIGKRKPFIILGVLFSGTTYVLVIFISTPILLLSLRGTQGAL-GASFAPAHSALISEL-S 147
Query: 124 ERKGSALGFFM----VGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAI 179
R GS GFF +G +G+ + IV V + + AFL SI+S +V IL + +
Sbjct: 148 TRVGSMFGFFNFVENMGFMVGNFLGGYIVKKVGI----KSAFLATSIVS-LVSILFLTQV 202
Query: 180 KGEPIKVEGV-------------KFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYLVSRG 226
K K + + K ++ F + + LG +L + S V
Sbjct: 203 KERERKKKNIGSFLPIREGRESEKVEMKSSAFKMLMKGELGAFYLSVLLAMIASGEVYAT 262
Query: 227 V--------GMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIV 278
V G E + + SL LGS++ G L D G+ L +LTF+
Sbjct: 263 VPVYFQEKFGEEFVGFLLGIDSLAAALGSLLIGRLIDKYGEKVFYKLAILGYILTFIGYA 322
Query: 279 IPSPLFLIPLGLVLYSVGGIM-----TAYTSEKASRENLGVVMGFVNMVGFFGATIGPYI 333
+ + ++ L +L V M + Y + + G MG +N + G IGP I
Sbjct: 323 WATTIIIMALVSLLSGVKWAMITSSASTYVARRVPHRERGQGMGLLNTMMTLGWVIGPLI 382
Query: 334 VGFLIDRLGYSLALLSVPLAYLVSAVI 360
G + D G+S+ L S L +VS ++
Sbjct: 383 GGLIADNFGFSVMLYSTTLPLIVSFLL 409
>sp|P31457|DGOT_ECOLI D-GALACTONATE TRANSPORTER
Length = 430
Score = 95.2 bits (233), Expect = 1e-18
Identities = 83/404 (20%), Positives = 171/404 (41%), Gaps = 47/404 (11%)
Query: 3 KLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGY 62
+ + L++I + + Y R + + I ++ GI AE+G + ++ Y+L Q+P G+
Sbjct: 14 RYLTLVMIFITVVICYVDRANLAVASAHIQEEFGITKAEMGYVFSAFAWLYTLCQIPGGW 73
Query: 63 IGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELF 122
D++G + I+I G+S+++ L+ +RA+ G F + +++ F
Sbjct: 74 FLDRVGSRVTYFIAIFGWSVATLFQGFATGLMSLIGLRAITGIFEAPAFPTNNRMVTSWF 133
Query: 123 RE-RKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLV---LSIMSSIVGILLM-- 176
E + SA+GF+ G +G +++ + LSW + F+V + I+ S++ +
Sbjct: 134 PEHERASAVGFYTSGQFVGLAFLTPLLIWIQEMLSWHWVFIVTGGIGIIWSLIWFKVYQP 193
Query: 177 -------------------------VAIKGE---PIKVEGVKFKIPRGVFLLSLANFLGL 208
+K E P+ + K R + + L F
Sbjct: 194 PRLTKGISKAELDYIRDGGGLVDGDAPVKKEARQPLTAKDWKLVFHRKLIGVYLGQFAVA 253
Query: 209 GAFFAMLTFLVSYLV-SRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYA 267
+ LT+ +YL +G+ KA M ++ L +G +++G++ D L + L +A
Sbjct: 254 STLWFFLTWFPNYLTQEKGITALKAGFMTTVPFLAAFVGVLLSGWVADLLVRKGFSLGFA 313
Query: 268 LNSLLTFLVIV---------IPSPLFLIPLGLVLYSVGG---IMTAYTSEKASRENLGVV 315
+ + +++ P+ ++ L + + G I + S A +G+
Sbjct: 314 RKTPIICGLLISTCIMGANYTNDPMMIMCLMALAFFGNGFASITWSLVSSLAPMRLIGLT 373
Query: 316 MGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAV 359
G N G G P +VG+L G++ AL+ + L+ A+
Sbjct: 374 GGVFNFAGGLGGITVPLVVGYLAQGYGFAPALVYISAVALIGAL 417
>pir||D65171 hypothetical 48.8 kD protein in ibpA-gyrB intergenic region -
Escherichia coli >gi|290540|gb|AAA62043.1| (L10328) f445
[Escherichia coli] >gi|1790126|gb|AAC76714.1| (AE000446)
D-galactonate transport [Escherichia coli K12]
Length = 445
Score = 95.2 bits (233), Expect = 1e-18
Identities = 83/404 (20%), Positives = 171/404 (41%), Gaps = 47/404 (11%)
Query: 3 KLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGY 62
+ + L++I + + Y R + + I ++ GI AE+G + ++ Y+L Q+P G+
Sbjct: 29 RYLTLVMIFITVVICYVDRANLAVASAHIQEEFGITKAEMGYVFSAFAWLYTLCQIPGGW 88
Query: 63 IGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELF 122
D++G + I+I G+S+++ L+ +RA+ G F + +++ F
Sbjct: 89 FLDRVGSRVTYFIAIFGWSVATLFQGFATGLMSLIGLRAITGIFEAPAFPTNNRMVTSWF 148
Query: 123 RE-RKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLV---LSIMSSIVGILLM-- 176
E + SA+GF+ G +G +++ + LSW + F+V + I+ S++ +
Sbjct: 149 PEHERASAVGFYTSGQFVGLAFLTPLLIWIQEMLSWHWVFIVTGGIGIIWSLIWFKVYQP 208
Query: 177 -------------------------VAIKGE---PIKVEGVKFKIPRGVFLLSLANFLGL 208
+K E P+ + K R + + L F
Sbjct: 209 PRLTKGISKAELDYIRDGGGLVDGDAPVKKEARQPLTAKDWKLVFHRKLIGVYLGQFAVA 268
Query: 209 GAFFAMLTFLVSYLV-SRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYA 267
+ LT+ +YL +G+ KA M ++ L +G +++G++ D L + L +A
Sbjct: 269 STLWFFLTWFPNYLTQEKGITALKAGFMTTVPFLAAFVGVLLSGWVADLLVRKGFSLGFA 328
Query: 268 LNSLLTFLVIV---------IPSPLFLIPLGLVLYSVGG---IMTAYTSEKASRENLGVV 315
+ + +++ P+ ++ L + + G I + S A +G+
Sbjct: 329 RKTPIICGLLISTCIMGANYTNDPMMIMCLMALAFFGNGFASITWSLVSSLAPMRLIGLT 388
Query: 316 MGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAV 359
G N G G P +VG+L G++ AL+ + L+ A+
Sbjct: 389 GGVFNFAGGLGGITVPLVVGYLAQGYGFAPALVYISAVALIGAL 432
>gb|AAD10060.1| (AF113952) multidrug-efflux transporter [Campylobacter jejuni]
Length = 431
Score = 94.8 bits (232), Expect = 1e-18
Identities = 92/355 (25%), Positives = 166/355 (45%), Gaps = 29/355 (8%)
Query: 22 MAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYS 81
+ +P L+ +K G N +GLL+ L ++Q+P G + DKIGRKK + I ++ +
Sbjct: 21 IVLPVLSLYALKLEGANEFLVGLLVGVYALTQMILQMPFGILSDKIGRKKTMLIGLIIFI 80
Query: 82 LSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISE-LFRERKGSALGFFMVGPAIG 140
+ S + + + ++ R L G AG A ATA+IS+ + E +G A+ ++G IG
Sbjct: 81 IGSLICSFAENIYTMLLGRMLQG--AGAIGAVATAMISDFITEENRGKAMA--VMGSFIG 136
Query: 141 SGITPLIVVPVALTLSWRYAFLV-LSIMSSIVGILLMVAIKGEPIKVEGVKFKIP----- 194
+V+ ++ W + L LS S++ I+L+ + + K+ K P
Sbjct: 137 LSFAASMVISPLMSAKWGLSSLFDLSAALSLLCIILLYTVVPKENKITHENEKTPFFHLI 196
Query: 195 --RGVFLLSLANF----LGLGAFFAMLTFLVSYLVSRGVGMEKASLMFSMLSLVGILGSI 248
+ + L++L NF L AF ++ LV +L G +K +++S + G +
Sbjct: 197 KQKNLALMNLTNFMQKMLMSIAFLSIPIILVKHL---GFASDKLWIVYSASMVAGFIAMG 253
Query: 249 IAGFLYDHLGKV-SVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSVG-----GIMTAY 302
AG L + G +LL + +L++L + + + +V++ +G IM +
Sbjct: 254 FAGSLGEKRGLAKQILLLGIVFFILSYLFFAFSNSIDFFIIAVVIFFIGFNLHEPIMQSC 313
Query: 303 TSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFL--IDRLGYSLALLSVPLAYL 355
S+ G +G N G+ G+ IG I G +D L LA++ V LA +
Sbjct: 314 ASKFCKVHEKGAALGLFNAFGYGGSFIGGIIGGIFLHLDTLNL-LAIILVILALI 367
>pir||D81282 probable efflux protein Cj1375 [imported] - Campylobacter jejuni
(strain NCTC 11168) >gi|6968809|emb|CAB73802.1|
(AL139078) putative efflux protein [Campylobacter
jejuni]
Length = 431
Score = 94.8 bits (232), Expect = 1e-18
Identities = 92/355 (25%), Positives = 166/355 (45%), Gaps = 29/355 (8%)
Query: 22 MAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYS 81
+ +P L+ +K G N +GLL+ L ++Q+P G + DKIGRKK + I ++ +
Sbjct: 21 IVLPVLSLYALKLEGANEFLVGLLVGVYALTQMILQMPFGILSDKIGRKKTMLIGLIIFI 80
Query: 82 LSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISE-LFRERKGSALGFFMVGPAIG 140
+ S + + + ++ R L G AG A ATA+IS+ + E +G A+ ++G IG
Sbjct: 81 IGSLICSFAENIYTMLLGRMLQG--AGAIGAVATAMISDFITEENRGKAMA--VMGSFIG 136
Query: 141 SGITPLIVVPVALTLSWRYAFLV-LSIMSSIVGILLMVAIKGEPIKVEGVKFKIP----- 194
+V+ ++ W + L LS S++ I+L+ + + K+ K P
Sbjct: 137 LSFAASMVISPLMSAKWGLSSLFDLSAALSLLCIILLYTVVPKENKITHENEKTPFFHLI 196
Query: 195 --RGVFLLSLANF----LGLGAFFAMLTFLVSYLVSRGVGMEKASLMFSMLSLVGILGSI 248
+ + L++L NF L AF ++ LV +L G +K +++S + G +
Sbjct: 197 KQKNLALMNLTNFMQKMLMSIAFLSIPIILVKHL---GFASDKLWIVYSASMVAGFIAMG 253
Query: 249 IAGFLYDHLGKV-SVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSVG-----GIMTAY 302
AG L + G +LL + +L++L + + + +V++ +G IM +
Sbjct: 254 FAGSLGEKKGLAKQILLLGIVFFILSYLFFAFSNSIDFFIIAVVIFFIGFNLHEPIMQSC 313
Query: 303 TSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFL--IDRLGYSLALLSVPLAYL 355
S+ G +G N G+ G+ IG I G +D L LA++ V LA +
Sbjct: 314 ASKFCKVHEKGAALGLFNAFGYGGSFIGGIIGGIFLHLDTLNL-LAIILVILALI 367
>pir||E75048 multidrug resistance protein PAB0913 - Pyrococcus abyssi (strain
Orsay) >gi|5458795|emb|CAB50282.1| (AJ248287) multidrug
resistance protein [Pyrococcus abyssi]
Length = 410
Score = 94.4 bits (231), Expect = 2e-18
Identities = 99/383 (25%), Positives = 171/383 (43%), Gaps = 42/383 (10%)
Query: 7 LILISLGWIF-NYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGD 65
+++ ++G F +++ + P L + MK +G +GLL L ++ Q P GY+ D
Sbjct: 28 ILMFAIGMFFADFAWGLGFPYLG-VYMKLIGGTMFLVGLLSVVYNLTSTIFQYPFGYLSD 86
Query: 66 KIGRKK-LLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPA-TALISELFR 123
K G++K + + IL + L+ L L+ +RA G G APA +ALISEL
Sbjct: 87 KTGKRKPFIILGILASGTTYGLVALITSPILLLGLRAFQGAL-GASLAPAHSALISEL-S 144
Query: 124 ERKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIK--- 180
R GS GFF +G + TL + F++ S++S ++GIL ++ IK
Sbjct: 145 PRIGSMFGFFGFVENLGFMAGNFAGGYIVKTLGMKMMFIITSLVS-LIGILFLLKIKERG 203
Query: 181 -----------------GEPIKVEGVKFKIPR----GVFLLS-LANFLGLGAFFAMLTFL 218
+ ++++ + FK G+F ++ L + GA +A
Sbjct: 204 RAKAGGDRLIIVKEGRESDRVELKEIAFKKLMKGRLGIFYVAVLLAMIASGAVYAT---- 259
Query: 219 VSYLVSRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIV 278
VS G E +F + SL L ++I G L D G+ + ++TF+
Sbjct: 260 VSVYFEEKFGEEFVGYLFGIDSLSAALSALIIGRLIDKYGEKLFFRLSLVGYIITFMGYA 319
Query: 279 IPSPLFLIPLGLVLYSVGGIM-----TAYTSEKASRENLGVVMGFVNMVGFFGATIGPYI 333
+ + + ++ L +L + M + Y + + G MG +N + G IGP I
Sbjct: 320 LANSVIIMALISILSGLKWTMLTNSSSTYVARRVPTSERGQGMGLLNTMMTLGWVIGPLI 379
Query: 334 VGFLIDRLGYSLALLS-VPLAYL 355
G L D G+++ L S VP+ +L
Sbjct: 380 GGILADNFGFAVMLYSTVPILFL 402
>pir||D83160 nitrite extrusion protein 1 PA3877 [imported] - Pseudomonas
aeruginosa (strain PAO1) >gi|2765452|emb|CAA75538.1|
(Y15252) nitrate extrusion protein [Pseudomonas
aeruginosa] >gi|9950057|gb|AAG07264.1|AE004805_2
(AE004805) nitrite extrusion protein 1 [Pseudomonas
aeruginosa]
Length = 431
Score = 90.5 bits (221), Expect = 3e-17
Identities = 88/374 (23%), Positives = 154/374 (40%), Gaps = 39/374 (10%)
Query: 6 ILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGD 65
+L + +L + N++ + I +LG++ ++ GL++ +L SL+++P G I D
Sbjct: 11 VLGMSTLSFAVNFAVWTMFSIIGIRIKDELGLSESQFGLMVALPILTGSLVRLPLGLITD 70
Query: 66 KIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELF-RE 124
+ G + + I +L ++ + YW + V L+ AG +A A S F +E
Sbjct: 71 RFGGRIVFFIHMLLVAIPIYGLAFASQYWHYL-VLGLFVGLAGGSFAVGIAYTSAWFEKE 129
Query: 125 RKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKGEPI 184
R+G+A+G F G A G+ IT L+ + + WR V S+ + +L + +P
Sbjct: 130 RQGTAMGIFGAGNA-GAAITNLVAPMIVVAFGWRMVPQVYSVAMLVTAVLFWLFTWTDPA 188
Query: 185 KVEGVKFKIPR-------------GVFLLSLANFLGLGAFFAMLTFLVSYLVSR-GVGME 230
++G R V+ L F G F A+ +L Y ++ G+ ++
Sbjct: 189 HLKGAAEASQRPNLAKQLAPLAELRVWRFGLYYFFVFGGFVALALWLPKYYIAEYGLDLK 248
Query: 231 KASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLI---- 286
AS + + +L L + G+ DH G SV L+ + P I
Sbjct: 249 TASFITMLFTLPSGLIRALGGWFSDHYGARSVNWGVFWVCLVCLFFLSYPQTTMTIHGIQ 308
Query: 287 ---PLGL--------VLYSVGGIMTAYTSEKASR-------ENLGVVMGFVNMVGFFGAT 328
LG+ L V GI + R N+G V G V ++G G
Sbjct: 309 GDLSLGIGLNVWLFTFLVFVVGIAQGFGKASVYRIIHDYYPSNMGTVGGMVGVIGGLGGF 368
Query: 329 IGPYIVGFLIDRLG 342
P + G+ D +G
Sbjct: 369 CLPILFGYAADHIG 382
>pir||F83064 probable MFS transporter PA4654 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9950908|gb|AAG08041.1|AE004879_7
(AE004879) probable MFS transporter [Pseudomonas
aeruginosa]
Length = 457
Score = 89.7 bits (219), Expect = 5e-17
Identities = 104/419 (24%), Positives = 183/419 (42%), Gaps = 73/419 (17%)
Query: 9 LISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLM-TSLLLPYSLIQVPAGYIGDKI 67
++ + ++ ++ R + L I +DL I++ E+ LLM S L Y+L +P G + D
Sbjct: 20 ILMVAYVLSFIDRQILNLLVGPIRRDLAISDTEMSLLMGLSFALFYTLCGIPLGRMADNR 79
Query: 68 GRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELF-RERK 126
R+ L+ +L +S +A L R YW +T R G A +LI++ F RER+
Sbjct: 80 SRRGLILFGVLVWSAMTAACGLARSYWQFLTFRVGVGVGEAALSPAAYSLIADSFPRERR 139
Query: 127 GSALGFFMVGPAIGSGITPL---IVVPVALTLS------------WRYAFLVLSIMSSIV 171
+A+ + +G +GSG+ L +V+ A W+ FL+L + ++
Sbjct: 140 ATAISVYSMGIYLGSGLAFLLGGLVIKFASAQGDVHLPLFGEVRPWQLIFLILG-AAGVL 198
Query: 172 GILLMVAIKGEPIKVEGVKFKIPRGV----------------FLLSLANFLGLGAFFAML 215
LL++AI+ + G +P G F + +F G G+ +
Sbjct: 199 FCLLLLAIREPARRGVGAGVAVPLGEVGAYLRANRKTVLCHNFGFACLSFAGYGSGAWVP 258
Query: 216 TFLVSYLVSRGVGMEKASLMF-SMLSLVGILGSIIAGFLYDHLGK---------VSVLLA 265
TF V + G +++ S++++ G LG + G L D+ K V +L A
Sbjct: 259 TFFVR---THGWDAGHVGVVYGSIVAVFGCLGIVFGGRLADYWAKRGRSDANMRVGLLAA 315
Query: 266 YA----------LNSLLTFLVIVIPSPLFL-IPLGLVLYSVGGIMTAYTSEKASRENLGV 314
+A L++ ++ P+ FL +P G+ ++ IM +AS L V
Sbjct: 316 WAVIPFTLVYPLLDNANWAAALMAPTVFFLSMPFGVAPAAIQEIMPNSMRGQASAIYLFV 375
Query: 315 VMGFVNMVGFFGATIGPYIVGFLID-------RLGYSLALLSVPLAYLVSAVIIGLDLR 366
V FG +GP V + D L YSL L+++ A L + V++G+ L+
Sbjct: 376 VT-------LFGLGVGPTAVALVTDFVFADDMALRYSLLLVTL-AAVLGAVVLLGIGLK 426
>pir||S74046 probable sugar transport protein c0110 - Sulfolobus solfataricus
>gi|1707740|emb|CAA69460.1| (Y08256) sugar transporter
[Sulfolobus solfataricus]
Length = 423
Score = 89.7 bits (219), Expect = 5e-17
Identities = 93/401 (23%), Positives = 178/401 (44%), Gaps = 41/401 (10%)
Query: 8 ILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKI 67
I+ S G++ + ++ A II+K+ + + GLL+ + L+ + G++ DK+
Sbjct: 17 IVTSAGFLLDGYDLNSISFAATIILKEFSLTTVKYGLLLAASLIGMIPGSIVFGWLSDKM 76
Query: 68 GRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRERK- 126
GR K++ + + + + L +++++ +L R L G G Y ++ L+SEL R
Sbjct: 77 GRSKIMGLDLFFFLVFGILTAISQNFVELFISRLLLGIGIGGDYPISSTLMSELSPSRSR 136
Query: 127 ----GSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKGE 182
++ + VG AI SGI L ++P + WRY FL+ +++S + +L + I+
Sbjct: 137 GRYLTGSVAMYWVGVAI-SGIATLFLLPTG-SYFWRYVFLIGALISVPIILLRLRLIESP 194
Query: 183 PIKVEGVKFKIP-----------RGVFLLSLANFLGLGAFFAMLTFLVSYLVSRGVGMEK 231
V K I RGV L L + F + FL + + G+G+
Sbjct: 195 RWLVSTGKANIKEINREIENKGVRGVVDLFKGKLLKITFFVTSVWFLFD-VAAYGIGLYY 253
Query: 232 ASLMFSM--------------LSLVGILGSIIAGFLYDHLG-KVSVLLAYALNSLLTFLV 276
+L+ ++ +LG IIA L D LG +V +L+ +LL +L
Sbjct: 254 PALLEEFAFPSKYEVVLGTLAIAAASVLGYIIAELLVDSLGRRVVLLVGLGFMTLLLYLG 313
Query: 277 IV------IPSPLFLIPLGLVLYSVGGIMTAYTSEKASRENLGVVMGFVNMVGFFGATIG 330
+ I P F+ + L ++ G + Y +E + GF + G+ +G
Sbjct: 314 GIYKFTGGILVPYFMSFVALEQWA-GAVTLFYPTELYPTPVRAIGQGFATAISRVGSVLG 372
Query: 331 PYIVGFLIDRLGYSLALLSVPLAYLVSAVIIGLDLRKTSYK 371
+ L ++G+ +L+ L++ +I L ++T+ K
Sbjct: 373 VFYFPILTKQMGFFNSLIMFGSVCLIAFIISILLSKETAKK 413
>gb|AAK42313.1| Sugar transport related protein [Sulfolobus solfataricus]
Length = 423
Score = 89.7 bits (219), Expect = 5e-17
Identities = 93/401 (23%), Positives = 178/401 (44%), Gaps = 41/401 (10%)
Query: 8 ILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKI 67
I+ S G++ + ++ A II+K+ + + GLL+ + L+ + G++ DK+
Sbjct: 17 IVTSAGFLLDGYDLNSISFAATIILKEFSLTTVKYGLLLAASLIGMIPGSIVFGWLSDKM 76
Query: 68 GRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRERK- 126
GR K++ + + + + L +++++ +L R L G G Y ++ L+SEL R
Sbjct: 77 GRSKIMGLDLFFFLVFGILTAISQNFVELFISRLLLGIGIGGDYPISSTLMSELSPSRSR 136
Query: 127 ----GSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKGE 182
++ + VG AI SGI L ++P + WRY FL+ +++S + +L + I+
Sbjct: 137 GRYLTGSVAMYWVGVAI-SGIATLFLLPTG-SYFWRYVFLIGALISVPIILLRLRLIESP 194
Query: 183 PIKVEGVKFKIP-----------RGVFLLSLANFLGLGAFFAMLTFLVSYLVSRGVGMEK 231
V K I RGV L L + F + FL + + G+G+
Sbjct: 195 RWLVSTGKANIKEINREIENKGVRGVVDLFKGKLLKITFFVTSVWFLFD-VAAYGIGLYY 253
Query: 232 ASLMFSM--------------LSLVGILGSIIAGFLYDHLG-KVSVLLAYALNSLLTFLV 276
+L+ ++ +LG IIA L D LG +V +L+ +LL +L
Sbjct: 254 PALLEEFAFPSKYEVVLGTLAIAAASVLGYIIAELLVDSLGRRVVLLVGLGFMTLLLYLG 313
Query: 277 IV------IPSPLFLIPLGLVLYSVGGIMTAYTSEKASRENLGVVMGFVNMVGFFGATIG 330
+ I P F+ + L ++ G + Y +E + GF + G+ +G
Sbjct: 314 GIYKFTGGILVPYFMSFVALEQWA-GAVTLFYPTELYPTPVRAIGQGFATAISRVGSVLG 372
Query: 331 PYIVGFLIDRLGYSLALLSVPLAYLVSAVIIGLDLRKTSYK 371
+ L ++G+ +L+ L++ +I L ++T+ K
Sbjct: 373 VFYFPILTKQMGFFNSLIMFGSVCLIAFIISILLSKETAKK 413
>pir||A83383 probable MFS transporter PA2114 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9948128|gb|AAG05502.1|AE004638_12
(AE004638) probable MFS transporter [Pseudomonas
aeruginosa]
Length = 423
Score = 89.3 bits (218), Expect = 6e-17
Identities = 91/370 (24%), Positives = 164/370 (43%), Gaps = 28/370 (7%)
Query: 29 PIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSLSSALIV 88
P ++ GI E G + T LL + AG + D+IGR L +++L ++ + L
Sbjct: 51 PTLIALWGIGTGEAGFIHTMTLLASAAGGWIAGILSDRIGRVLTLQLTVLWFAFFTFLCG 110
Query: 89 LTRDYWDLVTVRALYGFFAGLYYAPATALISELFRER-KGSALGFFMVGPAIGSGITPLI 147
L ++Y L+ R L GF G + LI E+ + R +G A+G G AIG G+T ++
Sbjct: 111 LAQNYEQLLVARTLMGFGFGGEWTAGAVLIGEVIKARDRGKAVGLVQSGWAIGWGLTAIL 170
Query: 148 VVPVALTL----SWRYAFLVLSIMSSIVGILLMVAIKGEPI------------KVEGVKF 191
+ L +WR A +L ++ ++ +++ +K I KV +
Sbjct: 171 YSLMFSLLPPEEAWR-ALFMLGLLPALFVLVVRRLVKEPEIYREARQRNQGADKVSFYEI 229
Query: 192 KIPRGVFLLSLANFL---GLGAFFAMLTFLVSYL-VSRGVGMEKASLMFSMLSLVGILGS 247
P + + A+ L LG ++A+ +L ++L RG+ + S +M+ L +G
Sbjct: 230 FAPGMLSITLRASLLTTGALGGYYAITAWLPTFLKTERGLTVLGTSGYLAMVILGSYVGY 289
Query: 248 IIAGFLYDHLGKVSVLLAYALNS-----LLTFLVIVIPSPLFL-IPLGLVLYSVGGIMTA 301
+++ FL D +G+ + +A+ S L T L + + L+L PLG + M +
Sbjct: 290 VVSAFLTDLIGRKKNFVLFAVGSFTVVLLYTQLPVSNGAMLWLGFPLGFFASGIFSGMGS 349
Query: 302 YTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVII 361
+ +E G GF G A + P ++G L +L L + + ++
Sbjct: 350 FLTELFPTRIRGSGQGFCYNAGRAIAALFPMLIGMLGQKLSLGLGIGAFAAVSYGVVILA 409
Query: 362 GLDLRKTSYK 371
L L +T K
Sbjct: 410 ALSLPETRGK 419
>pir||F71713 glycerol-3-phosphate transporter (glpT) RP054 - Rickettsia
prowazekii >gi|3860624|emb|CAA14525.1| (AJ235270)
GLYCEROL-3-PHOSPHATE TRANSPORTER (glpT) [Rickettsia
prowazekii]
Length = 429
Score = 87.8 bits (214), Expect = 2e-16
Identities = 86/410 (20%), Positives = 170/410 (40%), Gaps = 44/410 (10%)
Query: 3 KLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGY 62
++ IL I +G+ Y R P I + G+ +IG ++T+ + Y + + G+
Sbjct: 23 RIRILYSIVIGYATFYFCRQNFNIATPAIREYFGVTKTQIGWILTAASIMYGVSKACNGF 82
Query: 63 IGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELF 122
I DK+ + + + +L + + LI + W + + +F + + PAT +++ F
Sbjct: 83 ISDKVNARIFMVLGLLFVGIITILIGFSDFLWLIGILWIASNWFQSMGWPPATKMLTHWF 142
Query: 123 RERK-GSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKG 181
++ G+ IG + + + WR AF V +++ + + L ++
Sbjct: 143 AAKELGTKWAIGATSNQIGGALAMISCGYLIDKFDWRAAFFVPGLVACVASLFLYNRLRN 202
Query: 182 EPIK-----VEGVKFKIPRG---------------------VFLLSLAN----FLGLGAF 211
P + VE K P ++ + LAN + G
Sbjct: 203 SPKEVGLSTVEEYKEYPPEAIGNYERLLTKQLLKMVFCNKLIWYVCLANMFVYIIRSGVI 262
Query: 212 FAMLTFLVSYLVSRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHL-----GKVSVLLAY 266
+ TFL R + A L + ++GI G++IAG L D L G ++ +
Sbjct: 263 YWAPTFLKDL---RNISFVNAGLQIGLYEMIGIPGALIAGILSDKLFQGRRGPIASICMI 319
Query: 267 ALNSLLT-FLVIVIPSPLF-LIPLGLVLYSVGG---IMTAYTSEKASRENLGVVMGFVNM 321
L LL F + I S L ++ L L+ + V G ++ ++ ++R+ +G G +
Sbjct: 320 LLTLLLVLFWKVPIQSELLSILILALIGFFVAGPQLLVGIAAADFSTRQAVGTANGLSGL 379
Query: 322 VGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVIIGLDLRKTSYK 371
G+ GA I VG++ D G++ + ++ L+ V+ L ++ K
Sbjct: 380 FGYLGAAIAGVGVGWISDNYGWNGVFIFFSISALLGGVLFALTWNHSAEK 429
>pir||T46710 multidrug resistance transporter [imported] - Listeria
monocytogenes >gi|4914624|emb|CAB43715.1| (AJ009627)
multidrug resistance transporter [Listeria
monocytogenes]
Length = 397
Score = 87.4 bits (213), Expect = 2e-16
Identities = 83/363 (22%), Positives = 153/363 (41%), Gaps = 20/363 (5%)
Query: 24 VPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSLS 83
V L P I + +G +++++ +L T+ + +++ +P G + K+G KKL+ I + ++
Sbjct: 28 VDPLLPSIAESIGASHSQVEMLFTAYIFTMAIMMIPIGIVAGKMGDKKLIVIGLFIVTIF 87
Query: 84 SALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRERKGSALGFFMVGPAIGSGI 143
+ L L+ L RA +GF ++ A A ++ L E G A+G + +G
Sbjct: 88 ALLCGLSDTIGALSIFRAGWGFGNSMFMATAMTMLIAL-SETPGHAIGIYEASMGLGMAF 146
Query: 144 TPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKGEPIKV-----EGVKFKIPRGVF 198
PL+ + +SWRY F + + I +L++ +K EP KV E + I + +
Sbjct: 147 GPLL-GGILGNISWRYPFFATACLIFIAFLLILFKVK-EPKKVAPAPTEKNEVAIKQMLH 204
Query: 199 LLSLANFL-----GLGAFFAMLTFLVSYLVSRGVGMEKASLMFSMLSLVGILGS------ 247
L FL G+ ++ T L + G+ + +F L LGS
Sbjct: 205 LFKYRPFLQIAFSGMFYYYCFFTILAYSPLVLGLSAIQIGFVFFAWGLCLALGSAKVSHA 264
Query: 248 IIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSVGGIMTAYTSEKA 307
+ F + K S+L + +LL F+ ++ GL+L + T E +
Sbjct: 265 LEIRFNSKQILKGSLLACAVILALLGFIDNTAVDIGLIVISGLILGINNALFTTTVMEHS 324
Query: 308 SRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVIIGLDLRK 367
V G N V + GA P G L + LG + + + L ++ + L+
Sbjct: 325 PYAR-SVTSGAYNFVRWLGAAFAPLCSGLLSEALGMKMPFIVASIICLAGMGLLFIKLKP 383
Query: 368 TSY 370
+
Sbjct: 384 AHF 386
>pir||G71118 hypothetical protein PH0718 - Pyrococcus horikoshii
>gi|3257126|dbj|BAA29809.1| (AP000003) 398aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 398
Score = 87.4 bits (213), Expect = 2e-16
Identities = 89/379 (23%), Positives = 167/379 (43%), Gaps = 27/379 (7%)
Query: 6 ILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGD 65
+ +L + ++ + S M P + + L + G +M + SL +V GYI D
Sbjct: 17 VFLLGLVSFLNDMSSEMIAPIVPTYLTDILKMGKLASGSIMGLIESLSSLFKVIFGYISD 76
Query: 66 KIGRKKLLTISILGYSLSS---ALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELF 122
++K T LGY LS+ + LT +WD +T+R L G+ AP ALI+E
Sbjct: 77 VFRKRK--TFVALGYLLSTIAKGALALTHSWWDFLTLRILDRIGKGIRTAPRDALIAESS 134
Query: 123 RERK-GSALGFFMVGPAIGSGITPLIVVPVALTLS-------WRYAFLVLSIMSSIVGIL 174
+ K G + GF + +G+ PL+ V + LS +RY FL+ +I +I G+L
Sbjct: 135 EKGKSGKSFGFHRMMDTLGAVTGPLVAVGLLALLSKYPKELAYRYIFLISAIPGAI-GVL 193
Query: 175 LMVAIKGEPIKVEGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYLVSR----GVGME 230
+++ + + + K K + L FL + A A+ + ++ + + G +
Sbjct: 194 IVIFLVKDRGGIVKKKIKEISSLKSPHLRAFLAVVAIAALGRYSYAFTLWKVKELGYSIF 253
Query: 231 KASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIPLGL 290
+ +++ +++ L + G D +GK ++ + L L+ L ++ L
Sbjct: 254 QGLEFYALFNVIYALAAYPIGSYSDKVGKKKIITTGFGIAGLASLLFAYSKSLAMLMLAF 313
Query: 291 VLYSV-----GGIMTAYTSEKASRENLGVVMGFVNMVGFFGATIGP--YIVGFLIDRLGY 343
+LY V I AY ++ A G ++G + V FG + P IVG+L
Sbjct: 314 ILYGVYMAIEDTIPRAYMADLAKEYEKGTIIGMYHTV--FGIFVFPASIIVGYLWQTYSL 371
Query: 344 SLALLSVPLAYLVSAVIIG 362
+ L + ++ +++G
Sbjct: 372 EIGFLYASVMNFIAMILMG 390
>sp|P94131|MUCK_ACICA CIS,CIS-MUCONATE TRANSPORT PROTEIN >gi|1842056|gb|AAC27117.1|
(U87258) cis,cis-muconate transport protein MucK
[Acinetobacter sp. ADP1]
Length = 413
Score = 86.2 bits (210), Expect = 6e-16
Identities = 89/369 (24%), Positives = 160/369 (43%), Gaps = 32/369 (8%)
Query: 31 IMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSLSSALIVLT 90
I + ++ E G+L + L ++ + G+ D+ GR +++ ISIL +S+ + + LT
Sbjct: 43 IKAEFNLSTVEAGMLGSFTLAGMAIGGIFGGWACDRFGRVRIVVISILTFSILTCGLGLT 102
Query: 91 RDYWDLVTVRALYGFFAGLYYAPATALISELFRER-KGSALGFFMVGPAIGSGITPLIVV 149
+ + +R G Y L++E + + + LG G +G + L+
Sbjct: 103 QSFIQFGVLRFFASLGLGSLYIACNTLMAEYVPTKYRTTVLGTLQAGWTVGYIVATLLAG 162
Query: 150 PVALTLSWRYAFLVLSIMSSIVGILLMVAI---------------KGEPIKVEGVKF--- 191
+ WR F V +I+ ++ +L+ + + E +K K
Sbjct: 163 WLIPDHGWRVLFYV-AIIPVLMAVLMHFFVPEPAAWQQSRLAPSKQTETVKTSAFKLIFQ 221
Query: 192 -KIPRGVFLL--SLANFLGLGAFFAMLTFLVSYLVSRGVGMEKASLMFSMLSLVG--ILG 246
K R +F+L A FL G ++ + ++ SYL S +GM+ + M+ ILG
Sbjct: 222 DKRNRNMFILWALTAGFLQFG-YYGVNNWMPSYLESE-LGMKFKEMTAYMVGTYTAMILG 279
Query: 247 SIIAGFLYDHLGKVSVLLAYALNSLLTF-LVIVIPSP---LFLIPLGLVLYSVG-GIMTA 301
I+AGF+ D LG+ A+ + + L++ SP L+L+ + LY + G+
Sbjct: 280 KILAGFMADKLGRRFTYAFGAIGTAIFLPLIVFYNSPDNILYLLVIFGFLYGIPYGVNAT 339
Query: 302 YTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVII 361
Y +E G +G VG GA I P +GFL L + + AY + VI
Sbjct: 340 YMTESFPTAIRGTAIGGAYNVGRLGAAIAPATIGFLASGGSIGLGFVVMGAAYFICGVIP 399
Query: 362 GLDLRKTSY 370
L +++ Y
Sbjct: 400 ALFIKEKQY 408
>pir||E75042 transporter (major facilitator family) related PAB0874 - Pyrococcus
abyssi (strain Orsay) >gi|5458747|emb|CAB50234.1|
(AJ248287) TRANSPORTER (MAJOR FACILITATOR FAMILY)
related [Pyrococcus abyssi]
Length = 392
Score = 85.8 bits (209), Expect = 7e-16
Identities = 92/392 (23%), Positives = 177/392 (44%), Gaps = 41/392 (10%)
Query: 6 ILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGD 65
+ +L + ++ + S M P + + L I G +M + SL +V GYI D
Sbjct: 13 VFLLGLVSFLNDMSSEMIAPIVPSYLTDILKIGKLASGSIMGLIESLSSLFKVLFGYISD 72
Query: 66 KIGRKKLLTISILGY---SLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELF 122
K ++K LGY ++S + +T +WD + +R L G+ AP ALI+E
Sbjct: 73 KFRKRKAFVA--LGYLISTISKGALAVTHSWWDFLILRILDRIGKGIRTAPRDALIAESS 130
Query: 123 RERK-GSALGFFMVGPAIGSGITPLIVVPVAL-------TLSWRYAFLVLSIMSSIVG-- 172
+ K G + GF + +G+ PL+ + + L++RY FL+ S + ++G
Sbjct: 131 EKGKSGKSFGFHRMMDTLGAVAGPLVAMGLLALLANYPKELAYRYIFLI-SAVPGVIGVL 189
Query: 173 -ILLMVAIKGEPI--KVEGVK-FKIPRGVFLLSLANFLGLGAFFAMLTFL----VSYLVS 224
+LL+V KG + K++G+ K L + LG + T + Y V
Sbjct: 190 IVLLLVKDKGSEVKKKIKGISALKSSNLRIFLVIVAIAALGRYSYAFTLWKAEELGYSVF 249
Query: 225 RGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLG-KVSVLLAYALNSLLTFLVIVIPSPL 283
+G+G +++ +++ L + G+ D +G K+ + + + + L + L+ + L
Sbjct: 250 QGLG------FYALFNVIYALSAYPIGYYSDKVGKKIIITIGFGIAGLAS-LIFAYANNL 302
Query: 284 FLIPLGLVLYSV-----GGIMTAYTSEKASRENLGVVMGFVNMVGFFGATIGP--YIVGF 336
+ L VLY + I AY ++ A G V+G + V FG + P IVG+
Sbjct: 303 PTLLLAFVLYGLYMAIEDTIPRAYMADLAKEFEKGTVIGAYHTV--FGVFVFPASIIVGY 360
Query: 337 LIDRLGYSLALLSVPLAYLVSAVIIGLDLRKT 368
L ++ L + +++ +++ L ++++
Sbjct: 361 LWQTYSLTVGFLYSAVMNVIAMIMMALLIKES 392
>pir||S56504 hypothetical 46.6K protein (leuX-fecE intergenic region) -
Escherichia coli >gi|537120|gb|AAA97175.1| (U14003) TTG
start codon [Escherichia coli]
>gi|1790730|gb|AAC77235.1| (AE000498) putative transport
protein [Escherichia coli K12]
Length = 425
Score = 85.4 bits (208), Expect = 1e-15
Identities = 89/390 (22%), Positives = 168/390 (42%), Gaps = 41/390 (10%)
Query: 12 LGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKK 71
LG++F+ M + + II DLGI + + L+ T + + G + DK GRK
Sbjct: 42 LGYVFDGFDFMMIFYILHIIKADLGITDIQATLIGTVAFIARPIGGGFFGAMADKYGRKP 101
Query: 72 LLTISILGYSLSSALIVLTRDYWDLVTVRALYGF-FAGLYYAPATALISELFRERKGSAL 130
++ +I YS+ + L + + + L R + G +G Y +T + + + A
Sbjct: 102 MMMWAIFIYSVGTGLSGIATNLYMLAVCRFIVGLGMSGEYACASTYAVESWPKNLQSKAS 161
Query: 131 GFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAI-KGEPIKVEGV 189
F + G ++G+ I I+ A WR +F + ++ +LL++ I K P E +
Sbjct: 162 AFLVSGFSVGNIIAAQIIPQFAEVYGWRNSFFI-----GLLPVLLVLWIRKSAPESQEWI 216
Query: 190 KFKI-PRGVFL-------------LSLANFLGLGAFFAMLTFLVSYLVSRGVGMEKASLM 235
+ K + FL + L F GA + + L SYL GV S +
Sbjct: 217 EDKYKDKSTFLSVFRKPHLSISMIVFLVCFCLFGANWPINGLLPSYLADNGVNTVVISTL 276
Query: 236 FSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIP------LG 289
++ L + G+I GF+ D K+ V A+ + + +F+ + PLF I +G
Sbjct: 277 MTIAGLGTLTGTIFFGFVGD---KIGVKKAFVVGLITSFIFL---CPLFFISVKNSSLIG 330
Query: 290 LVLY-------SVGGIMTAYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLG 342
L L+ + G++ + + + G+ G + +G G P + ++ G
Sbjct: 331 LCLFGLMFTNLGIAGLVPKFIYDYFPTKLRGLGTGLIYNLGATGGMAAPVLATYISGYYG 390
Query: 343 YSLALLSVPLAY-LVSAVIIGLDLRKTSYK 371
++L V +A+ + +++G D+ YK
Sbjct: 391 LGVSLFIVTVAFSALLILLVGFDIPGKIYK 420
>sp|P39352|YJHB_ECOLI HYPOTHETICAL METABOLITE TRANSPORT PROTEIN IN LEUX-FECE INTERGENIC
REGION
Length = 405
Score = 85.4 bits (208), Expect = 1e-15
Identities = 89/390 (22%), Positives = 168/390 (42%), Gaps = 41/390 (10%)
Query: 12 LGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKK 71
LG++F+ M + + II DLGI + + L+ T + + G + DK GRK
Sbjct: 22 LGYVFDGFDFMMIFYILHIIKADLGITDIQATLIGTVAFIARPIGGGFFGAMADKYGRKP 81
Query: 72 LLTISILGYSLSSALIVLTRDYWDLVTVRALYGF-FAGLYYAPATALISELFRERKGSAL 130
++ +I YS+ + L + + + L R + G +G Y +T + + + A
Sbjct: 82 MMMWAIFIYSVGTGLSGIATNLYMLAVCRFIVGLGMSGEYACASTYAVESWPKNLQSKAS 141
Query: 131 GFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAI-KGEPIKVEGV 189
F + G ++G+ I I+ A WR +F + ++ +LL++ I K P E +
Sbjct: 142 AFLVSGFSVGNIIAAQIIPQFAEVYGWRNSFFI-----GLLPVLLVLWIRKSAPESQEWI 196
Query: 190 KFKI-PRGVFL-------------LSLANFLGLGAFFAMLTFLVSYLVSRGVGMEKASLM 235
+ K + FL + L F GA + + L SYL GV S +
Sbjct: 197 EDKYKDKSTFLSVFRKPHLSISMIVFLVCFCLFGANWPINGLLPSYLADNGVNTVVISTL 256
Query: 236 FSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIP------LG 289
++ L + G+I GF+ D K+ V A+ + + +F+ + PLF I +G
Sbjct: 257 MTIAGLGTLTGTIFFGFVGD---KIGVKKAFVVGLITSFIFL---CPLFFISVKNSSLIG 310
Query: 290 LVLY-------SVGGIMTAYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLG 342
L L+ + G++ + + + G+ G + +G G P + ++ G
Sbjct: 311 LCLFGLMFTNLGIAGLVPKFIYDYFPTKLRGLGTGLIYNLGATGGMAAPVLATYISGYYG 370
Query: 343 YSLALLSVPLAY-LVSAVIIGLDLRKTSYK 371
++L V +A+ + +++G D+ YK
Sbjct: 371 LGVSLFIVTVAFSALLILLVGFDIPGKIYK 400
>pir||D83518 cis,cis-muconate transporter MucK PA1019 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9946930|gb|AAG04408.1|AE004534_6 (AE004534)
cis,cis-muconate transporter MucK [Pseudomonas
aeruginosa]
Length = 451
Score = 84.7 bits (206), Expect = 2e-15
Identities = 92/402 (22%), Positives = 164/402 (39%), Gaps = 37/402 (9%)
Query: 4 LIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYI 63
LI + LG + + M + + + G++N E G L + L ++ + G+
Sbjct: 20 LIAFVFCFLGLLADGVDLMFLAYSLNSLKAEFGLSNFEAGSLGSLTLAGMAVGGIYGGWC 79
Query: 64 GDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFR 123
D+ GR +++T +I+ +S+ +AL+ LT++YW +R + G + L+SE
Sbjct: 80 CDRFGRVRVVTWTIVLFSIGTALLGLTQNYWQFALIRFVASLGLGSLFVACNILMSECVG 139
Query: 124 ER-KGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKGE 182
R + + L G +G + L+ + WR F ++ ++V + L +
Sbjct: 140 TRYRTTILAAMQAGWTVGYLVATLLAGQIIPEFGWRTLFFT-AVAPALVCLALRPWVPES 198
Query: 183 PIKVE------------------------GVKFKIP--RGVFLL-SLANFLGLGAFFAML 215
P + G P RG+FLL SL + L ++
Sbjct: 199 PSWLAAQAGRQRPGAAPQSHAEAGGAGPLGRMLGDPETRGMFLLWSLTSCFLLFGYYGTN 258
Query: 216 TFLVSYLVSRGVGMEKASLMFSMLSLVG--ILGSIIAGFLYDHLGKVSVLLAYALNSLLT 273
++ SYL S +GM S+ M+ ILG + AG D G+ A A+ S
Sbjct: 259 NWMPSYLESE-LGMNFKSMTGYMVGTYSAMILGKVAAGVCADLFGRRLTFAAGAIGSAAF 317
Query: 274 FLVIVI---PSPL--FLIPLGLVLYSVGGIMTAYTSEKASRENLGVVMGFVNMVGFFGAT 328
+IV PS + LI G + G++ Y +E S G +G +G GA
Sbjct: 318 MPLIVFYHSPSNILWILITFGFIYGVPVGVLATYMTESFSTRVRGSAVGTAYNLGRIGAA 377
Query: 329 IGPYIVGFLIDRLGYSLALLSVPLAYLVSAVIIGLDLRKTSY 370
+ P +G L + L + + Y+++ +I L + Y
Sbjct: 378 VAPAGIGLLATHVSIGAGFLVMGITYVLTGLIPALFIADRLY 419
>gi|11497979 oxalate/formate antiporter (oxlT-2) [Archaeoglobus fulgidus]
>gi|7448836|pir||G69295 oxalate/formate antiporter
(oxlT-2) homolog - Archaeoglobus fulgidus
>gi|2650264|gb|AAB90866.1| (AE001079) oxalate/formate
antiporter (oxlT-2) [Archaeoglobus fulgidus]
Length = 397
Score = 84.7 bits (206), Expect = 2e-15
Identities = 92/371 (24%), Positives = 155/371 (40%), Gaps = 38/371 (10%)
Query: 31 IMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTIS----ILGYSLSSAL 86
+M G + L + LL ++L+ VPAG D+IG +K+ + +G+ LS +
Sbjct: 31 LMNTFGWSKTIASLPFSIFLLIFALMMVPAGRTQDRIGPRKVAMLGGVLLGVGFLLSGLI 90
Query: 87 IVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRERKGSALGFFMVGPAIGSGITPL 146
+ YW + + + G GL YA + + F ER G A G + +G G++ L
Sbjct: 91 ESIQSPYWLIFSYGVIAGAGCGLGYACPIPVARKWFPERVGLATGLVV----MGFGMSAL 146
Query: 147 IVVPVALTLSWRY----AFLVLSIMSSIVGIL----------LMVAIKGEPIKVEGVKFK 192
I P+ L Y F +L ++ IV + L P KVE V K
Sbjct: 147 IFAPLERILIDTYGISTTFYILGVILLIVAVFAASLLSNPPELPAVQASNPAKVEVVTGK 206
Query: 193 IPRG---------VFLLSLANFLGLGAFFAMLTFLVSYLVSRGVGMEKASLMFSMLSLVG 243
G ++L L+ F A ++ + Y RG+ A+ S+LS+
Sbjct: 207 PELGPSEMLRDYRFYVLWLSFFFMALAGLMVIGHIAPYAQERGLEPLAAAFAVSILSVAN 266
Query: 244 ILGSIIAGFLYDHLGKVSVLLAYAL---NSLLTFLVIVIPSPLFLIPLGLVLYSVG---G 297
+G AG L D +G+ + L +L+ F + + I ++ ++ G
Sbjct: 267 AVGRPGAGALSDKIGRAMTMFVLFLIQGITLIAFPHVALTLITIYICAAIIGFNYGANFS 326
Query: 298 IMTAYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLG-YSLALLSVPLAYLV 356
+ + T + +NLGV G V G +GP + G++ D G Y +A L + L+
Sbjct: 327 LFPSATGDFFGTKNLGVNYGLVFTSYGVGGLVGPIMAGYVFDVTGSYEIAFLVAGVLALI 386
Query: 357 SAVIIGLDLRK 367
+A + L RK
Sbjct: 387 AAFMSFLLRRK 397
>dbj|BAB05122.1| (AP001511) multidrug resistance protein [Bacillus halodurans]
Length = 403
Score = 84.7 bits (206), Expect = 2e-15
Identities = 98/407 (24%), Positives = 184/407 (45%), Gaps = 73/407 (17%)
Query: 2 EKLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAG 61
+ L+ ++L + + M +P L P I + G++ + G L+TS +P +L+ +G
Sbjct: 6 DTLLYVVLGMAPLLMVLGNSMFIPML-PTIQAEWGLSVVQGGWLLTSFTVPAALLIPISG 64
Query: 62 YIGDKIGRKK--LLTISILGYSL---SSALIVLTRDYWDLVTVRALYGFFAGLYYAPATA 116
+ ++ G+K+ L ++ ILG S A+++ TR +W L+T R + G G +
Sbjct: 65 ILSERYGQKRIGLASLVILGTGCVLSSIAVVIETRPFWLLLTGRIIQGLGTGGLTPISLM 124
Query: 117 LISELFR-ERKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMS--SIVGI 173
+ SELF +++ ALGF V IG I+P I+ + L SW Y+F+VL ++ + VG
Sbjct: 125 VASELFSGKKRNEALGFLEVSNGIGKIISP-IIGGLILLASWYYSFVVLFALALLAFVGF 183
Query: 174 LLMVAIKGEPIK------------------VEGVKFKIPRGV-----------FLLSLAN 204
+V EP K E K +P + +L +++N
Sbjct: 184 YTLV---NEPKKHETTLSARAYTKKLSQSLQENWKMFVPIFIIGSLGMLILFGYLFAVSN 240
Query: 205 FLG------LGAFFA---MLTFLVSYLVSRGVGMEKASLMFSMLSLVGILGSIIAGFLYD 255
+G G A +L + S+ SR + E AS F +VG +++ G ++
Sbjct: 241 MIGEVSPFWKGVILAVPFLLFAVASFWTSRWLTPEFAS--FQKAMMVGT--TLMTGAMF- 295
Query: 256 HLGKVSVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSVGGIMTAYTSEKASRENLGVV 315
L+ + + + F+++ LF + LG+ + A T+ + V+
Sbjct: 296 -------LMLWQHDRTILFMLV----SLFSLGLGMFFPPASAAVAALTNNVSR----SVI 340
Query: 316 MGFVNMVGFFGATIGPYIVGFLIDR--LGYSLALLSVPLAYLVSAVI 360
M +M F G +GP I GF ++R ++++ + L++ + V+
Sbjct: 341 MPLYSMARFLGVAVGPVIFGFWLERNISIHTMSFFIISLSFFIMCVL 387
>sp|P27669|UHPC_SALTY REGULATORY PROTEIN UHPC >gi|421217|pir||C41853 hexose phosphate
transport system regulatory protein uhpC - Salmonella
typhimurium >gi|154410|gb|AAA27245.1| (M89480)
hexosephosphate transport protein [Salmonella
typhimurium]
Length = 442
Score = 84.3 bits (205), Expect = 2e-15
Identities = 81/398 (20%), Positives = 170/398 (42%), Gaps = 43/398 (10%)
Query: 6 ILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGD 65
ILI I LG+ Y R + + AP I+ + ++IGLL T + Y + + +G + D
Sbjct: 31 ILITIWLGYALFYFTRKSFNAAAPEILASGILTRSDIGLLATLFYITYGVSKFVSGIVSD 90
Query: 66 KIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELF-RE 124
+ + + I ++ + + L + W + AL FF G L++ + R
Sbjct: 91 RSNARYFMGIGLIATGVVNILFGFSTSLWAFALLWALNAFFQGFGSPVCARLLTAWYSRT 150
Query: 125 RKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKGEPI 184
+G + +G + PL++ VAL WR +V +++ VG++L ++ P
Sbjct: 151 ERGGWWALWNTAHNVGGALIPLVMAAVALHYGWRVGMMVAGLLAIGVGMVLCWRLRDRPQ 210
Query: 185 KV----------EGVKFKIPRGVFLLS----LANFLGLGAFFAMLT--FLVSYLV----- 223
+ + ++ + LS LA ++ L + +L+ +++ Y+V
Sbjct: 211 AIGLPPVGDWRHDALEVAQQQEGAGLSRKEILAKYVLLNPYIWLLSLCYVLVYVVRAAIN 270
Query: 224 ---------SRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGK-----------VSVL 263
+ GV + A+ SM L G +G+++AG+ D L +L
Sbjct: 271 DWGNLYMSETLGVDLVTANTAVSMFELGGFIGALVAGWGSDKLFNGNRGPMNLIFAAGIL 330
Query: 264 LAYALNSLLTFLVIVIPSPLFLIPLGLVLYSVGGIMTAYTSEKASRENLGVVMGFVNMVG 323
L+ L+ F V+ + F G ++ ++ +E + +E G GFV +
Sbjct: 331 LSVGSLWLMPFASYVMQAACF-FTTGFFVFGPQMLIGMAAAECSHKEAAGAATGFVGLFA 389
Query: 324 FFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVII 361
+ GA++ + + +++ ++ + +A +SA+++
Sbjct: 390 YLGASLSGWPLAKVLEIWHWTGFFAVIAIAAGISALLL 427
>gb|AAB48105.1| (U41818) PhlE [Pseudomonas fluorescens]
Length = 423
Score = 83.9 bits (204), Expect = 3e-15
Identities = 99/394 (25%), Positives = 178/394 (45%), Gaps = 35/394 (8%)
Query: 3 KLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGY 62
++++L+ +S G + R + L P+IM DL ++ ++GLL L + + G
Sbjct: 17 RMVVLLSLSFGLVG--LDRFIIMPLFPVIMHDLALDYQDLGLLSAILAFAWGGSALFMGV 74
Query: 63 IGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELF 122
++G K+LL +SI SL + L LV +RAL G G + P + ++++
Sbjct: 75 AIRRLGTKQLLVLSITLVSLLAGASALISSLMGLVLLRALMGICEGA-FTPVSIIVTDEV 133
Query: 123 RE--RKGSALGFFM-VGPAIGSGITPLIV-VPVALTLSWRYAFLVLSIMSSIVGILLMVA 178
+ R+G LG + P IG + PL+ V + SWR F ++S+ +V L
Sbjct: 134 SQPCRRGLNLGIQQALFPIIGLCLGPLLAGVLFEMFGSWRAVFAIISLPGLLVAWYLYRT 193
Query: 179 IKGEP-------IKVEGVKFK--IPRGVFLLSLANFLG-LGAFFAMLTFLVSYLVS-RGV 227
+ ++ G +++ + G L++A L L F + L SYL +
Sbjct: 194 YQPSQAPHPRPLVEPSGSQWRTALSSGNVRLNIALMLCILTCQFVLCALLPSYLTDVLHL 253
Query: 228 GMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVL-LAYALNSLLTFLVIV---IPSPL 283
+++ S + L G G ++ L D LG+ V+ + + +++LL L+I+ +P L
Sbjct: 254 SNFSMAMIISAIGLGGFFGQLVIPGLSDQLGRKPVVSICFLISTLLVGLLIISPPLPWLL 313
Query: 284 FL-------IPLGLVLYSVGGIMTAYTSEKASRENLGVVMGFVNMVG-FFGATIGPYIVG 335
FL I L+ +VG + TSE L G V G G + P + G
Sbjct: 314 FLQLFFLSFINFSLICITVGPL----TSESVPPSLLATATGLVVGCGEILGGGVAPVVAG 369
Query: 336 FLIDRLGYSLALLSVPLAYLVSAVIIGLDLRKTS 369
++ G + A+L + LA + ++ L L++ S
Sbjct: 370 YIAVNWGLT-AILFLALAGSLMGGLLSLRLKEAS 402
>pir||G64494 quinolone resistance protein norA homolog - Methanococcus
jannaschii >gi|1592184|gb|AAB99579.1| (U67596)
multidrug-efflux transporter (bmr1) [Methanococcus
jannaschii]
Length = 386
Score = 83.9 bits (204), Expect = 3e-15
Identities = 89/370 (24%), Positives = 156/370 (42%), Gaps = 40/370 (10%)
Query: 1 MEKLIILILISLGWIFNYSHRMAVPSLAPIIM---KDLGINNAEIGLLMTSLLLPYSLIQ 57
+EK + +I WI ++ + V +API+ + LG N EIGL+ S L ++ Q
Sbjct: 4 LEKNVFVI-----WITTFTTMLGVGFIAPIMAIYAQTLGATNLEIGLIFGSFALARTVAQ 58
Query: 58 VPAGYIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATAL 117
+P G + D G+K + Y +S+ + + VR G F+ A +
Sbjct: 59 IPVGVLSDIYGKKFFIVCGTFFYGVSTLMYNFVSTVLGFLIVRIFTGIFSAFVTPVAGSY 118
Query: 118 ISELF-RERKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFL---VLSIMSSIVGI 173
I+ + + R G +G F +G GI P I +A + F L I+++I+
Sbjct: 119 IAAIAPKTRLGEYMGIFNSAITLGFGIGPFIGGILADMYGIKMPFYFCGFLGILAAIISY 178
Query: 174 LLMVAI----KGEPIKV---------EGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVS 220
+ + I E I V E +K + F+++++N + +A +L
Sbjct: 179 MKLEDIVFNKNKEKIDVKKISTLFSFEFLKNRNFSSSFIINVSNVMINAGIYA---YLAL 235
Query: 221 YLVSRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLA--------YALNSLL 272
Y ++ + + + M ++ +++ L G LYD LG + +++ Y L++
Sbjct: 236 YAINYNITISQVGFMIALTNILMALLQRSFGKLYDKLGNIMIIIGIFIISFGMYLLSTST 295
Query: 273 TFLVIVIPSPLFLIPLGLVLYSVGGIMTAYTSEKASRENLGVVMGFVNMVGFFGATIGPY 332
TFL I+ + L +I +G + S A R+ G MG G IG
Sbjct: 296 TFLTIL--ASLTIIAVGSSISSTATTSLAVKDIPTHRK--GEAMGLFTTSINIGMFIGAV 351
Query: 333 IVGFLIDRLG 342
GFL D LG
Sbjct: 352 SFGFLADILG 361
>sp|O51798|MMLH_ALCEU PROBABLE 4-METHYLMUCONOLACTONE TRANSPORTER
>gi|2808585|emb|CAA67957.1| (X99639) transport protein
[Ralstonia eutropha]
Length = 428
Score = 83.9 bits (204), Expect = 3e-15
Identities = 80/339 (23%), Positives = 151/339 (43%), Gaps = 43/339 (12%)
Query: 13 GWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKL 72
GW + L P + G+ AE+G+L T L+ ++ AG + D+ GR ++
Sbjct: 22 GWALDSFDMQMFSFLLPALTLTWGLTKAEVGVLGTVALVVTAIGGWGAGILSDRYGRARI 81
Query: 73 LTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRER-KGSALG 131
L ++I+ ++L L + Y L+ R L G G +A AL++E+ R +G A+G
Sbjct: 82 LVLAIIWFTLFGVLAGFAQSYQQLLIARTLQGLGFGGEWAVGAALMAEVIDSRHRGKAIG 141
Query: 132 F----FMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKGEPIKVE 187
F F +G A+ + L++ + ++WR AF I+ +++ + + +K +
Sbjct: 142 FVQSGFALGWALAVVVATLLLAWLPKEMAWRVAFW-SGIIPALIVLFIRRHVKDSSMFER 200
Query: 188 GVKFKIPR----GVF------LLSLANFLGLG---AFFAMLTFLVSYLVSRGVGMEKASL 234
+ + PR VF L+L++ L +G +A+L +L S L R V +
Sbjct: 201 ARQSRAPRASLSSVFNRKYARTLALSSVLVIGLQAGCYAILVWLPSLLNQRQVAAGSMIV 260
Query: 235 MFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYS 294
+++ G + L D +G+ L+ LL+ ++ L+PL L +
Sbjct: 261 TVFIMAFGSFCGFAVTADLSDRIGRRPTLI------LLSVCAWIVTVSYMLLPLNTTLTA 314
Query: 295 VGGIMTAYTSEKASRENLGVVMGFVNMVGFFGATIGPYI 333
+ LG ++GF + +G F A +GP++
Sbjct: 315 I----------------LGFLVGF-SAIGMF-AALGPFL 335
>sp|P39637|YWFA_BACSU HYPOTHETICAL 44.5 KD PROTEIN IN ROCC-PTA INTERGENIC REGION
>gi|629086|pir||S39734 chloramphenicol resistance
homolog ywfA - Bacillus subtilis
>gi|414003|emb|CAA51635.1| (X73124) ipa-79d [Bacillus
subtilis] >gi|2636311|emb|CAB15802.1| (Z99123) alternate
gene name: ipa-79d~similar to chloramphenicol resistance
[Bacillus subtilis]
Length = 412
Score = 83.1 bits (202), Expect = 5e-15
Identities = 83/393 (21%), Positives = 174/393 (44%), Gaps = 37/393 (9%)
Query: 4 LIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYI 63
L++ + +++G S + + L P + K ++++ +L S+ + +I + A +
Sbjct: 17 LLLALALTMGVFAAGSEELVISPLLPDLAKAF---SSDVSVLALSISIYGVMIFIGAPLL 73
Query: 64 ---GDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISE 120
GDK R+ L ++ + + + + L ++ + RAL G AG + A A++ +
Sbjct: 74 VPLGDKYSRELSLLAGLMIFIIGTVICALAQNIFFFFLGRALSGLAAGAFVPTAYAVVGD 133
Query: 121 LFRER-KGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAI 179
+G +G + ++ + + L WR+ F + ++M +V +L+++ +
Sbjct: 134 RVPYTYRGKVMGLIVSSWSLALIFGVPLGSFIGGVLHWRWTFWIFALMGVLVVLLILLEM 193
Query: 180 KG-------------EPIKVEGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYLVSRG 226
+ EP K+PR +++ F + F+ M +FL +YL
Sbjct: 194 RRHAQHKNSGKEEIEEPAGTFRDALKVPRVPVYITIT-FCNMIGFYGMYSFLGTYLQDVF 252
Query: 227 VGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKV-SVLLAYALNSLLTFLVIVIPSPLFL 285
G A+ +F M+ +G S+I G + D +GK+ S+L+A + S+L + P+ +FL
Sbjct: 253 TGGNTAAGLFIMIYGIGFSMSVITGKIADRIGKMRSLLIALGVISVLLACLPYAPASMFL 312
Query: 286 IPLGLVLYSVGGIMTAYT-------SEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLI 338
+ L ++ G+M + T S + G VM F ++ T+G ++G +
Sbjct: 313 LIASLFIW---GLMQSLTVTLLSTILSDCSERHRGKVMVFYSLASNLAVTLGSALMGPVY 369
Query: 339 DRLGYSLALLSVPLAYLVSAVIIGLDLRKTSYK 371
GY+ L + ++G L +YK
Sbjct: 370 VAYGYAAVGL-----ICAAITVLGFVLSVFAYK 397
>sp|P42609|EXUT_ECOLI HEXURONATE TRANSPORTER >gi|7428805|pir||B65098 hexuronate
transporter - Escherichia coli (strain K-12)
>gi|1160319|dbj|BAA02588.1| (D13328) aldohexuronate
transport system [Escherichia coli]
>gi|2367193|gb|AAC76128.1| (AE000391) transport of
hexuronates [Escherichia coli K12]
Length = 472
Score = 82.7 bits (201), Expect = 6e-15
Identities = 82/398 (20%), Positives = 171/398 (42%), Gaps = 42/398 (10%)
Query: 6 ILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGD 65
++ L++LG + Y R V + AP +M++L I+ + ++ + Y+++Q AGY+ D
Sbjct: 51 MIALVTLGTVLGYLTRNTVAAAAPTLMEELNISTQQYSYIIAAYSAAYTVMQPVAGYVLD 110
Query: 66 KIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRER 125
+G K + + +++ L + L R G SE F +
Sbjct: 111 VLGTKIGYAMFAVLWAVFCGATALAGSWGGLAVARGAVGAAEAAMIPAGLKASSEWFPAK 170
Query: 126 KGS-ALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMV------- 177
+ S A+G+F VG +IG+ I P +VV + SW+ AF++ +S I + ++
Sbjct: 171 ERSIAVGYFNVGSSIGAMIAPPLVVWAIVMHSWQMAFIISGALSFIWAMAWLIFYKHPRD 230
Query: 178 -----------AIKGEPIKVE-GVKFKIPRGVFL-------LSLANFLGLGAFFAMLTFL 218
I G+ + + K+ G L ++L FL A+ ++
Sbjct: 231 QKHLTDEERDYIINGQEAQHQVSTAKKMSVGQILRNRQFWGIALPRFLAEPAWGTFNAWI 290
Query: 219 VSYLVS-RGVGMEKASLMFSMLSLVGILGSIIAGF---LYDHLGKVSVLLAYALNSLLTF 274
++ G +++ ++ M L LG I+ G+ L+ V+++++ + L
Sbjct: 291 PLFMFKVYGFNLKEIAMFAWMPMLFADLGCILGGYLPPLFQRWFGVNLIVSRKMVVTLGA 350
Query: 275 LVIVIPSPLFLIP---LGLVLYSVGGI--------MTAYTSEKASRENLGVVMGFVNMVG 323
++++ P + L + ++L +GG + +S+ R + G M
Sbjct: 351 VLMIGPGMIGLFTNPYVAIMLLCIGGFAHQALSGALITLSSDVFGRNEVATANGLTGMSA 410
Query: 324 FFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVII 361
+ +T+ +VG L D +G+S + + L+ A++I
Sbjct: 411 WLASTLFALVVGALADTIGFSPLFAVLAVFDLLGALVI 448
>sp|P42613|GARP_ECOLI PROBABLE GALACTARATE TRANSPORTER (D-GALACTARATE PERMEASE)
>gi|7442469|pir||C65102 hypothetical 49.0 kD protein in
rnpB-sohA intergenic region - Escherichia coli
>gi|606067|gb|AAA57930.1| (U18997) ORF_f444 [Escherichia
coli] >gi|1789515|gb|AAC76161.1| (AE000394) putative
transport protein [Escherichia coli K12]
Length = 444
Score = 82.7 bits (201), Expect = 6e-15
Identities = 88/413 (21%), Positives = 175/413 (42%), Gaps = 56/413 (13%)
Query: 3 KLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGY 62
+ +IL++I + NY+ R + + K+L ++ +G + ++ Y L+Q+P G+
Sbjct: 16 RYLILLIIFIVTAVNYADRATLSIAGTEVAKELQLSAVSMGYIFSAFGWAYLLMQIPGGW 75
Query: 63 IGDKIGRKKLLTISILGYSLSSAL---IVLTRDYW---DLVTVRALYGFFAGLYYAPATA 116
+ DK G KK+ T S+ +SL + L + + W + +R + GF +
Sbjct: 76 LLDKFGSKKVYTYSLFFWSLFTFLQGFVDMFPLAWAGISMFFMRFMLGFSEAPSFPANAR 135
Query: 117 LISELF-RERKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILL 175
+++ F + +G+A F + ++ + W + F V+ ++ ++ L
Sbjct: 136 IVAAWFPTKERGTASAIFNSAQYFSLALFSPLLGWLTFAWGWEHVFTVMGVIGFVLTALW 195
Query: 176 MVAIKGEP----IKVEGVKFKIPRGVFL---------------------LSLANFLGLGA 210
+ I + E +KF G + L+N + LG
Sbjct: 196 IKLIHNPTDHPRMSAEELKFISENGAVVDMDHKKPGSAAASGPKLHYIKQLLSNRMMLGV 255
Query: 211 FFA----------MLTFLVSYLV-SRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGK 259
FF LT+ YLV +G+ + K L+ S+ +L G G ++ G D+L K
Sbjct: 256 FFGQYFINTITWFFLTWFPIYLVQEKGMSILKVGLVASIPALCGFAGGVLGGVFSDYLIK 315
Query: 260 VSVLLAYA------LNSLLTFLVIVI----PSPLFLIPLGLVLY--SVGGIMTAYTSEKA 307
+ L A L LL +I+ + L ++ + L + G + S+ A
Sbjct: 316 RGLSLTLARKLPIVLGMLLASTIILCNYTNNTTLVVMLMALAFFGKGFGALGWPVISDTA 375
Query: 308 SRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRL-GYSLALLSVPLAYLVSAV 359
+E +G+ G N+ G + + P ++G+L+ L ++ AL+ V + L++ V
Sbjct: 376 PKEIVGLCGGVFNVFGNVASIVTPLVIGYLVSELHSFNAALVFVGCSALMAMV 428
>gb|AAA57897.1| (U18997) ORF_o472 [Escherichia coli]
Length = 472
Score = 82.3 bits (200), Expect = 8e-15
Identities = 82/398 (20%), Positives = 171/398 (42%), Gaps = 42/398 (10%)
Query: 6 ILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGD 65
++ L++LG + Y R V + AP +M++L I+ + ++ + Y+++Q AGY+ D
Sbjct: 51 MIALVTLGTVLGYLTRNTVAARAPTLMEELNISTQQYSYIIAAYSAAYTVMQPVAGYVLD 110
Query: 66 KIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRER 125
+G K + + +++ L + L R G SE F +
Sbjct: 111 VLGTKIGYAMFAVLWAVFCGATALAGSWGGLAVARGAVGAAEAAMIPAGLKASSEWFPAK 170
Query: 126 KGS-ALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMV------- 177
+ S A+G+F VG +IG+ I P +VV + SW+ AF++ +S I + ++
Sbjct: 171 ERSIAVGYFNVGSSIGAMIAPPLVVWAIVMHSWQMAFIISGALSFIWAMAWLIFYKHPRD 230
Query: 178 -----------AIKGEPIKVE-GVKFKIPRGVFL-------LSLANFLGLGAFFAMLTFL 218
I G+ + + K+ G L ++L FL A+ ++
Sbjct: 231 QKHLTDEERDYIINGQEAQHQVSTAKKMSVGQILRNRQFWGIALPRFLAEPAWGTFNAWI 290
Query: 219 VSYLVS-RGVGMEKASLMFSMLSLVGILGSIIAGF---LYDHLGKVSVLLAYALNSLLTF 274
++ G +++ ++ M L LG I+ G+ L+ V+++++ + L
Sbjct: 291 PLFMFKVYGFNLKEIAMFAWMPMLFADLGCILGGYLPPLFQRWFGVNLIVSRKMVVTLGA 350
Query: 275 LVIVIPSPLFLIP---LGLVLYSVGGI--------MTAYTSEKASRENLGVVMGFVNMVG 323
++++ P + L + ++L +GG + +S+ R + G M
Sbjct: 351 VLMIGPGMIGLFTNPYVAIMLLCIGGFAHQALSGALITLSSDVFGRNEVATANGLTGMSA 410
Query: 324 FFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVII 361
+ +T+ +VG L D +G+S + + L+ A++I
Sbjct: 411 WLASTLFALVVGALADTIGFSPLFAVLAVFDLLGALVI 448
>pir||B83017 probable MFS transporter PA5030 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9951319|gb|AAG08415.1|AE004916_4
(AE004916) probable MFS transporter [Pseudomonas
aeruginosa]
Length = 438
Score = 81.1 bits (197), Expect = 2e-14
Identities = 87/362 (24%), Positives = 166/362 (45%), Gaps = 21/362 (5%)
Query: 24 VPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSLS 83
+ + P++ K I+ AE L ++ +L + G I D IGRK ++ +S+L +L
Sbjct: 66 IQPMMPVLSKAFSISAAESSLALSVATAMLALGLLVTGPISDAIGRKPVMVVSLLAAALF 125
Query: 84 SALIVLTRDYWDLVTVRALYGF-FAGLYYAPATALISELFRERKGSALGFFMVGPAIGSG 142
+ + + ++ +RAL G +GL T L E+ + G ++G ++ G AIG
Sbjct: 126 TLGSAVMPTWHGVLLMRALVGLSLSGLAAVAMTYLSEEIHPQHIGLSMGLYIGGNAIGGM 185
Query: 143 ITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAI------KGEPIK----VEGVKFK 192
LI + +SW A VL ++ + ++ + + P+K + G +
Sbjct: 186 SGRLISGVLVDFISWHAALAVLGGLALVAALVFWRVLPESKHFRPAPLKPATLLNGYRLH 245
Query: 193 I-PRGVFLLSLANFLGLGAFFAMLTFLVSYLVSRGVGMEKASL-MFSMLSLVGILGSIIA 250
G+ L L FL +G+F + ++ L++ M +A + + S++ L GI S
Sbjct: 246 FRDAGLPWLFLIGFLLMGSFVTLFNYIGYRLLAEPYHMSQAVVGVLSVVYLSGIYSSAWV 305
Query: 251 GFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSVG-----GIMTAYTSE 305
G L D LG+ VL A L +L L++ + P+ L+ GL+L++ G + +++
Sbjct: 306 GSLADKLGRRKVLWAVIL-LMLGGLLLTLFEPIPLMLAGLLLFTFGFFGAHSVASSWIGR 364
Query: 306 KASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVIIGLDL 365
+A R G + G+++ + G G++ L + + LV AV++ L L
Sbjct: 365 RALRAK-GQASSLYLFSYYVGSSLAGTLGGVFWHYYGWNGIGLFIG-SLLVVAVLVSLHL 422
Query: 366 RK 367
+
Sbjct: 423 AR 424
>gi|11498923 multidrug resistance protein [Archaeoglobus fulgidus]
>gi|7483887|pir||D69415 multidrug resistance protein
homolog - Archaeoglobus fulgidus
>gi|2649251|gb|AAB89920.1| (AE001012) multidrug
resistance protein [Archaeoglobus fulgidus]
Length = 371
Score = 80.4 bits (195), Expect = 3e-14
Identities = 86/365 (23%), Positives = 146/365 (39%), Gaps = 19/365 (5%)
Query: 7 LILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDK 66
++ + L F Y+ V + P LG + L ++ P G + +
Sbjct: 1 MLRLILSGFFAYASLSCVIPIIPSYASSLGASVFLSAFAAGVFALFPAIAMTPFGMLSEV 60
Query: 67 IGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRE-R 125
GR++ L + L+S L + + LV R L+G + LY AL++++ E R
Sbjct: 61 YGRRRFLVAGAVTSLLASLLYLQSSTAELLVFSRTLHGLGSALYIPSINALVADISEESR 120
Query: 126 KGSALG--------FFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMV 177
+G A+G F GP G ++ V L+ LV S + + + +
Sbjct: 121 RGEAMGKLQTALMLGFFAGPLAGGFVSDFFGVKAVFLLA-----LVFSAAALVPVVGVRE 175
Query: 178 AIKGEPIKVEGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVS-YLVSRGVGMEKASLMF 236
KG I G +F PR + L F+G+ ++ F + Y + ++A L+
Sbjct: 176 RSKGGEI---GKQFIFPRKLAPLFAVMFVGMATGSSLALFAIPFYAPELNISQQQAGLLV 232
Query: 237 SMLSLVGILGSIIAGFLYDHLGK-VSVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSV 295
++L L + + AG L D G+ V+ LL + L F P + L
Sbjct: 233 AVLFLFSAIIRVPAGILADRAGRNVTALLGMVVTGLGLFSAFKPDFPFLFLASLLCGAGN 292
Query: 296 GGIMTAYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYL 355
G + TA + + EN G MG N V G G + GF+ L + +L + A L
Sbjct: 293 GIVNTAVFAAASDYENRGYAMGVANTVLNAGIFAGTTLAGFMAGFLSFQSMMLILAAATL 352
Query: 356 VSAVI 360
+ + I
Sbjct: 353 LFSPI 357
>pir||T47026 hypothetical protein [imported] - Yersinia pestis
>gi|4106614|emb|CAA21369.1| (AL031866) ORF46, len= 409
aa, similar to many transport protein, eg: AEMML_1
Ralstonia eutropha, (428 aa), 44.2 % identity in 407 aa
overlap, Fasta scores: opt: 1217E(): 0, or U32790_4
Haemophilus influenzae Rd section 1 (407 aa), 33.0%
identity in 40>
Length = 409
Score = 80.4 bits (195), Expect = 3e-14
Identities = 84/362 (23%), Positives = 155/362 (42%), Gaps = 27/362 (7%)
Query: 13 GWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKL 72
GW + M + +M I+ + G+L T LL ++ AG + D+ GR ++
Sbjct: 21 GWALDALDFMVFTFVIATLMALWQIDAGQAGMLSTVTLLFSAIGGWGAGILADRYGRVRI 80
Query: 73 LTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFR-ERKGSALG 131
L I+IL +SL + LI +++ + +RAL G G +A + L+ E+ R E +G A+G
Sbjct: 81 LQITILWFSLCTVLIGFAQNFEHVFILRALQGLGFGGEWAVGSVLMGEIVRAEHRGKAVG 140
Query: 132 FFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKGEPIKVEGVKF 191
G AIG G L+ + LS +A+ L + + +L++ K P +K
Sbjct: 141 TVQSGWAIGWGAAALLYTLMFSVLSEEWAWRALFWIGVLPALLVLYIRKNVPEPALFLKS 200
Query: 192 K-------------------IPRGVFLLSLANFLGLGAFFAMLTFLVSYL-VSRGVGMEK 231
+ + + L SL G ++A+ T+L ++L + R + +
Sbjct: 201 RHEQQAKDRRVSSFAIFSPALLKTTVLASLLCTGVQGGYYAITTWLPTFLKLERNLSVIG 260
Query: 232 ASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLT---FLVIVIPSPLFLI-- 286
++ +G I +L D LG+ + L+ ++L S +T + + + + L+
Sbjct: 261 TGGYLMVIIFGSFVGYICGAYLTDKLGRRANLIIFSLLSCITIFAYTQLTLTNTQMLVLG 320
Query: 287 -PLGLVLYSVGGIMTAYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYSL 345
PLG + M A+ +E GF G + P +VG+L +
Sbjct: 321 FPLGFSASGIFSGMGAFLTELFPSAVRATGQGFTYSFGRAVGALFPGLVGYLSQSSSLAF 380
Query: 346 AL 347
A+
Sbjct: 381 AI 382
>sp|P39398|YJJL_ECOLI HYPOTHETICAL 49.4 KD PROTEIN IN TSR-MDOB INTERGENIC REGION
>gi|7428806|pir||F65250 hypothetical 49.4 kD protein in
tsr-mdoB intergenic region - Escherichia coli
>gi|2367379|gb|AAC77312.1| (AE000506) putative transport
protein, cryptic, orf, joins former yjiZ and yjjL
[Escherichia coli K12]
Length = 453
Score = 80.4 bits (195), Expect = 3e-14
Identities = 86/395 (21%), Positives = 166/395 (41%), Gaps = 65/395 (16%)
Query: 7 LILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDK 66
++L+ + NY R ++ I ++LG++ EIG L++ L Y + Q+P G + D+
Sbjct: 44 MLLLFFAAVINYLDRSSLSVANLTIREELGLSATEIGALLSVFSLAYGIAQLPCGPLLDR 103
Query: 67 IGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFR-ER 125
G + +L + + +SL A+ + ++ V VR G +I++ F +
Sbjct: 104 KGPRLMLGLGMFFWSLFQAMSGMVHNFTQFVLVRIGMGIGEAPMNPCGVKVINDWFNIKE 163
Query: 126 KGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGI-LLMVAIKGEPI 184
+G +GFF IG ++P I+ + L + WR F+ + ++ + I M+ E +
Sbjct: 164 RGRPMGFFNAASTIGVAVSPPILAAMMLVMGWRGMFITIGVLGIFLAIGWYMLYRNREHV 223
Query: 185 KVEGVK-----------------FKIPRGVFLL-----SLANFLGLG-AFFAMLTFLVSY 221
++ V+ F R +F + F G+ + L +L Y
Sbjct: 224 ELTAVEQAYLNAGSVNARRDPLSFAEWRSLFRNRTMWGMMLGFSGINYTAWLYLAWLPGY 283
Query: 222 L-VSRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHL----------GKVSVLLAYALNS 270
L + + ++ LM ++ L G G ++ G++ D L K+ ++ ++
Sbjct: 284 LQTAYNLDLKSTGLMAAIPFLFGAAGMLVNGYVTDWLVKGGMAPIKSRKICIIAGMFCSA 343
Query: 271 LLTFL----------VIVIPSPLFLIPL------GLVLYSVGGIMTAYTSEKASRENLGV 314
T + V++I LF I GL+ +V MTA ++G
Sbjct: 344 AFTLIVPQATTSMTAVLLIGMALFCIHFAGTSCWGLIHVAVASRMTA---------SVGS 394
Query: 315 VMGFVNMVGFFGATIGPYIVGFLIDRL-GYSLALL 348
+ F + F A+ P I GF++D + LAL+
Sbjct: 395 IQNFAS---FICASFAPIITGFIVDTTHSFRLALI 426
>pir||D75358 probable fosmidomycin resistance protein - Deinococcus radiodurans
(strain R1) >gi|6459517|gb|AAF11300.1|AE002016_2
(AE002016) fosmidomycin resistance protein, putative
[Deinococcus radiodurans]
Length = 409
Score = 80.0 bits (194), Expect = 4e-14
Identities = 82/379 (21%), Positives = 162/379 (42%), Gaps = 34/379 (8%)
Query: 6 ILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGD 65
I + ++ G N ++ + L P + G+ A + LL + L S++Q G +G+
Sbjct: 36 IALAVTAGHFINDAYGAMLTPLTPALQSKYGVTIAAVTLLSSVFSLTSSVLQPLLGIVGE 95
Query: 66 KIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELF-RE 124
+I R+ + L + L+ + L+ + A+ GF +G ++ +A +++ +
Sbjct: 96 RIDRRYAAALGPLMTGVGLTLMGFVPWFGALILLVAVAGFGSGFFHPAGSAYVAQNSPAD 155
Query: 125 RKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKGEPI 184
++G F G G + P+ L W +++ +++ + V
Sbjct: 156 KRGLWASIFSAGGTAGMALGPVFAGVGLTHLPW------FALIGAVIAAVTFVVTPSGAQ 209
Query: 185 KVEGVKFKIPRGVFLLSLANFLGLG--------AFFAMLTFLVSYLVSRGVGMEKASLMF 236
K + V G+F L G+ + AML F+ L++RG G +
Sbjct: 210 KAKRVGLAEYAGIFRGPLVWLWGMAVLRSLASMGYNAMLPFM---LMARGFGAREVGTTL 266
Query: 237 SMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPL--FLIPLGLVLYS 294
++ ++ G I+ G L D G+ VL A L+++ F V+++ SP + PL ++
Sbjct: 267 AIYAVASAFGGILGGRLSDKYGRTPVLRAAILSTIPFFAVLILSSPADWWFYPL---TFA 323
Query: 295 VGGIMTA------YTSEKASRENLGVVMGFVNMVGFFGATIG--PYIVGFLIDRLGYSLA 346
VG + A T+++ + +++ V M+GF G ++VG L D A
Sbjct: 324 VGAAVNASIPVGVVTAQEYAPQHVAVASSI--MMGFSWGIAGVLVFVVGALADVTTPQTA 381
Query: 347 LLSVPLAYLVSAVIIGLDL 365
L+ LA L+ + +I L
Sbjct: 382 ALA-SLALLIPSALIAYRL 399
>pir||D72302 hypothetical protein TM1021 - Thermotoga maritima (strain MSB8)
>gi|2695718|emb|CAA04933.1| (AJ001694) putative membrane
protein [Thermotoga maritima]
>gi|4981562|gb|AAD36098.1|AE001764_1 (AE001764)
permease, putative [Thermotoga maritima]
Length = 422
Score = 79.6 bits (193), Expect = 5e-14
Identities = 96/404 (23%), Positives = 169/404 (41%), Gaps = 53/404 (13%)
Query: 1 MEKLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPA 60
M + ILIL+ L N + P++ I ++ I +A+IGL+ +S + +L+ +
Sbjct: 1 MAVIFILILMVL---LNADQMVMSPNIGAI-EQEFNITDAQIGLVASSFTVIGALVSLVW 56
Query: 61 GYIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISE 120
GY+ D+ RK LL SIL + + +R Y +L RAL G G + ++I +
Sbjct: 57 GYLADRYSRKNLLIYSILVGEIPCLMSAFSRSYGELFFWRALTGIGVGASFPIVYSMIGD 116
Query: 121 LFRE-RKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAI 179
+F E ++G + +IGS + ++ + WR F+ +S+ + +L + +
Sbjct: 117 MFDEVKRGKVVALISSAISIGSVLGMIVGGFLGPKYGWRVPFIAVSVPNIFFAVLSIFVL 176
Query: 180 K-----------GEPIK--------------VEGVKFKIPRGVFLLSLANFLGLGAFFAM 214
K GE ++ + VK K +F +A + G A+
Sbjct: 177 KEPKRGAFEKGIGELVQSGYEYPKAPKLSDYAKLVKVKTNLLLFFQGIAGTIPWG---AI 233
Query: 215 LTFLVSYL-VSRGVGMEKASLMFSMLSLVGILGSIIAGF----LYDHLGKVSVLLAYALN 269
FLV + RG+ +E A+L+F + L I+G I+ G +Y L
Sbjct: 234 PYFLVEFFRRERGLSVETATLVFLVFGLGNIVGIILGGLWGASIYAKSRPFLPLFCSITT 293
Query: 270 SLLTFLVIV----IPSPLFLIPLGLVLYSVGGI-------MTAYTSEKASRENLGVVMGF 318
+L TF ++ + S L L+ LG + + M +E R G +
Sbjct: 294 ALGTFFTVMTLDYMGSLLVLMLLGFIASFTASLTGPNVKFMLLNVNEPQER---GRIFSI 350
Query: 319 VNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAY-LVSAVII 361
N+ G G + G + LG A L V + L+ AV++
Sbjct: 351 FNLTDSLGTGFGKFAGGVMSVALGSLGAALKVSAYFWLICAVLL 394
>gb|AAF58060.1| (AE003808) CG8428 gene product [Drosophila melanogaster]
Length = 552
Score = 79.6 bits (193), Expect = 5e-14
Identities = 79/365 (21%), Positives = 148/365 (39%), Gaps = 44/365 (12%)
Query: 15 IFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLT 74
+ NY R + + + D I N GLL T ++ Y + GY+GD+ R ++
Sbjct: 125 LINYMDRFTIAGVLTDVRNDFDIGNDSAGLLQTVFVISYMVCAPIFGYLGDRYSRPWIMA 184
Query: 75 ISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELF-RERKGSALGFF 133
+ + +S ++ L + + + RAL G Y A +IS+LF + + L F
Sbjct: 185 VGVGLWSTTTLLGSFMKQFGWFIAFRALVGIGEASYSTIAPTIISDLFVHDMRSKMLALF 244
Query: 134 MVGPAIGSGITPLIVVPVA-LTLSWRYAFLVLSIMSSIVGILLMVAIKGEPIK------- 185
+GSG+ ++ A L WR+A V I+ IV + L++ IK +P++
Sbjct: 245 YFAIPVGSGLGYIVGSKTAHLANDWRWALRVTPIL-GIVAVFLILLIK-DPVRGHSEGSH 302
Query: 186 -------VEGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYLVSRGVGME-------- 230
+ +K + F+LS A F + L + + G+ M+
Sbjct: 303 NLEATTYKQDIKALVRNRSFMLSTAGFTCVAFVAGALAWWGPSFIYLGMKMQPGNENIVQ 362
Query: 231 -----KASLMFSMLSLVGI-LGSIIAGFL---YDHLGKVSVLLAYALNSLLTFLVIVIPS 281
K L+ + L+G+ LGS +A L Y++ + +++ + F +V+P
Sbjct: 363 DDISYKFGLVAMLAGLIGVPLGSFLAQRLRGRYENCDPYICAVGLFISAPMVFAALVVPQ 422
Query: 282 P------LFLIPLGLVLYSVGGIMTAYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVG 335
F+ + L I+ + N GV+ + G G +G ++
Sbjct: 423 TSESLCFFFVFVAQVALNLCWSIVADILLVRCVAFNFGVI---TMLAGLLGVPLGSFLSQ 479
Query: 336 FLIDR 340
+L+ R
Sbjct: 480 YLVKR 484
>gb|AAK41596.1| Transport membrane protein (permease) [Sulfolobus solfataricus]
Length = 374
Score = 79.2 bits (192), Expect = 7e-14
Identities = 74/363 (20%), Positives = 159/363 (43%), Gaps = 14/363 (3%)
Query: 10 ISLGWIFNYSH---RMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDK 66
I +GWI + R++ ++ I +N+ +IGL+ T+ + Y L +P G I D+
Sbjct: 5 IIVGWIGTFLQLFLRLSWGVISLPIALLFHLNSIQIGLVATAFYIGYVLSSIPWGLIIDR 64
Query: 67 IGRKKLLT-ISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRER 125
IG + + SI+ ++ L + DY L+ + G + A +++ +
Sbjct: 65 IGPSRAVEYASIILVGMNLLLFLYLTDYTILLIAYLIEGLITASIFPSAMKIVAVSYSHS 124
Query: 126 KGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGIL---LMVAIKGE 182
+V A I L ++ L WR+ +L +++ ++ IL +++ G
Sbjct: 125 SKFTFYVALVESAGPITIITLGIIASFLLHLWRFIYLAMAVSFGLIAILSHFSRISVSGT 184
Query: 183 PIKVEGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYLV-SRGVGMEKASLMFSMLSL 241
IK + + R + + +L L + + T++ LV RG+ ++L + +
Sbjct: 185 EIK-RSFRVILNRKITMATLVRLGELWSTWGTTTWIFPMLVLYRGISPTLSALFLLLFGV 243
Query: 242 VGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIP----LGLVLYSVGG 297
++G + L + G +V+L + ++ +I+ + + ++P LG+ +S
Sbjct: 244 GQLVGILSVEKLVERFGDSNVILINLIGFIILTFLIIFSNDIDILPEAFLLGIFSFSYRP 303
Query: 298 IMTAYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRL-GYSLALLSVPLAYLV 356
+ + A + G +GF N V G I P VG ++ +S+++L++ ++
Sbjct: 304 PTDSLIMKIAGESSAGTSIGFANAVSQIGTMIAPSFVGLVLYLTHSFSISMLALDAGCVI 363
Query: 357 SAV 359
S V
Sbjct: 364 SIV 366
>sp|P37948|GLPT_BACSU GLYCEROL-3-PHOSPHATE TRANSPORTER (G-3-P TRANSPORTER) (G-3-P
PERMEASE) >gi|2119807|pir||I40417 glycerol-3-phosphate
transport protein glpT - Bacillus subtilis
>gi|403372|emb|CAA81291.1| (Z26522) glycerol 3-phosphate
permease [Bacillus subtilis] >gi|2632500|emb|CAB12008.1|
(Z99105) glycerol-3-phosphate permease [Bacillus
subtilis] >gi|3599636|dbj|BAA33111.1| (AB006424) ybeE
[Bacillus subtilis]
Length = 444
Score = 78.4 bits (190), Expect = 1e-13
Identities = 79/408 (19%), Positives = 170/408 (41%), Gaps = 48/408 (11%)
Query: 3 KLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGY 62
+L + I I +G+ Y R P + + G + E+GL++ ++ + Y + G
Sbjct: 27 RLQVFIGIFIGYAGYYLLRKNFAFAIPYLQEQ-GFSKTELGLVLAAVSIAYGFSKFIMGM 85
Query: 63 IGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALY----GFFAGLYYAPATALI 118
+ D+ + L + ++ + L V VT+ ++ G+F G+ + P +
Sbjct: 86 VSDRCNPRYFLATGLFLSAIVNILFVSMPWVTSSVTIMFIFMFINGWFQGMGWPPCGRTM 145
Query: 119 SELFR-ERKGSALGFFMVGPAIGSGI-TPLIVVPVALTLSWRYAFLVLSIMSSIVGILLM 176
+ F +G+ + + V IG GI PL+ + +A+ ++W+ F +I++ I+ L++
Sbjct: 146 AHWFSISERGTKMSIWNVAHNIGGGILAPLVTLGIAMFVTWKSVFFFPAIIAIIISFLIV 205
Query: 177 VAIKGEPIK-----VEGVKFKIPRGVF---------------LLSLANFLGLGAFFAMLT 216
+ ++ P +E + P+ F + FL AF +
Sbjct: 206 LLVRDTPQSCGLPPIEEYRNDYPKHAFKNQEKELTTKEILFQYVLNNKFLWYIAFANVFV 265
Query: 217 FLVSYLV----------SRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAY 266
+ V Y V ++G E + + + GI G+I+ G++ D K A
Sbjct: 266 YFVRYGVVDWAPTYLTEAKGFSPEDSRWSYFLYEYAGIPGTILCGWISDRFFKSRRAPAG 325
Query: 267 ALNSLLTFLVIVI------PSPLF----LIPLGLVLYSVGGIMTAYTSEKASRENLGVVM 316
L F+ +++ +PL LI +G ++Y ++ + A ++ G
Sbjct: 326 VLFMAGVFIAVLVYWLNPAGNPLVDNIALISIGFLIYGPVMLIGLQAIDLAPKKAAGTAA 385
Query: 317 GFVNMVGFF-GATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVIIGL 363
G G+ G+ I+GF++DR ++ + + + +++ V + L
Sbjct: 386 GLTGFFGYIGGSAFANAIMGFVVDRFNWNGGFIMLISSCILAIVFLAL 433
>sp|P46907|NARK_BACSU NITRITE EXTRUSION PROTEIN (NITRITE FACILITATOR)
>gi|2127151|pir||S60080 nitrite extrusion protein narK -
Bacillus subtilis >gi|971337|emb|CAA90041.1| (Z49884)
nitrite extrusion protein [Bacillus subtilis]
>gi|2636269|emb|CAB15760.1| (Z99123) nitrite extrusion
protein [Bacillus subtilis] >gi|1586090|prf||2203266A
dissimilatory nitrate reductase [Bacillus subtilis]
Length = 395
Score = 78.4 bits (190), Expect = 1e-13
Identities = 81/374 (21%), Positives = 159/374 (41%), Gaps = 23/374 (6%)
Query: 5 IILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIG 64
I L L SL + + + + SL I D+ ++ EI L+ ++ SL+++P GY+
Sbjct: 7 IQLSLQSLSLVAGFMVWVLISSLISQITLDIHLSKGEISLVTAIPVILGSLLRIPLGYLT 66
Query: 65 DKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRE 124
++ G + + +S + I + +DL+ G ++ T+L +E
Sbjct: 67 NRFGARLMFMVSFILLLFPVFWISIADSLFDLIAGGFFLGIGGAVFSIGVTSLPKYYPKE 126
Query: 125 RKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKGEPI 184
+ G G + G IG+ +T +A + W+ + I+ ++ +L ++
Sbjct: 127 KHGVVNGIYGAG-NIGTAVTTFAAPVIAQAVGWKSTVQMYLILLAVFALLHVLFGDRHEK 185
Query: 185 KVE-GVKFKIP-----RGVFLLSLANFLGLGAFFAMLTFLVSYLVSR-GVGMEKASLMFS 237
KV+ VK +I ++ LSL F+ GAF A +L ++LV G+ A L +
Sbjct: 186 KVKVSVKTQIKAVYRNHVLWFLSLFYFITFGAFVAFTIYLPNFLVEHFGLNPADAGLRTA 245
Query: 238 MLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSVGG 297
V L GFL D + + +L+ L+ +++ + L G + +V
Sbjct: 246 GFIAVSTLLRPAGGFLADKMSPLRILMFVFTGLTLSGIILSFSPTIGLYTFGSLTVAVCS 305
Query: 298 ---------IMTAYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLG-YSLAL 347
++ Y S++A G+ G V+ +G G P I+ + G Y++
Sbjct: 306 GIGNGTVFKLVPFYFSKQA-----GIANGIVSAMGGLGGFFPPLILASVFQATGQYAIGF 360
Query: 348 LSVPLAYLVSAVII 361
+++ L S V++
Sbjct: 361 MALSEVALASFVLV 374
>dbj|BAB13277.1| (AP001119) hypothetical protein [Buchnera sp. APS]
Length = 410
Score = 78.0 bits (189), Expect = 2e-13
Identities = 85/388 (21%), Positives = 176/388 (44%), Gaps = 28/388 (7%)
Query: 5 IILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIG 64
+IL L S G+ +S V S+ P+ K + AE L +++ + SL + G +
Sbjct: 26 VILALFSGGFA-TFSILYCVQSILPMFSKQFYLTPAESSLALSAATITMSLGMLFTGPLS 84
Query: 65 DKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGF-FAGLYYAPATALISELFR 123
D IGRK +++ S+ ++ + + + + +V +RAL G +G+ T + E+
Sbjct: 85 DIIGRKSIMSTSLFIAAMLTMICSMMTSWISIVLLRALTGLALSGVVAVAMTYISEEIHP 144
Query: 124 ERKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGI---------- 173
+G ++ G IG + L+ +A SW + +V+ + S I
Sbjct: 145 NSLSFCMGLYISGNTIGGFLGRLLSSILAEKFSWSISLMVIGLFSFISSCFFLYFLPPSK 204
Query: 174 -LLMVAIKGEPIKVEGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYLVSRGVGMEKA 232
L V+I R +F L + F+ +G+F + ++ L+ + ++
Sbjct: 205 NFLSVSINFHKCLHRFYLQLKNRVLFFLFIIGFILMGSFVTIFNYIGYRLMLEPFFLCQS 264
Query: 233 SL-MFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIPLGLV 291
S+ + S + L G+ S AG L + + ++L+ +L ++ L I + LF+I LGL+
Sbjct: 265 SIGLLSTIYLTGVYSSPKAGVLINKYNRNNILIV-SLMLMIIGLFITQYNQLFIIILGLI 323
Query: 292 LYSVGGIMTAYTSEKA---SRENLGVVMGFVNMVGFF--GATIGPYIVGFL---IDRLGY 343
++S GG ++++ + S N+ + + F+ G+++ GF + LG
Sbjct: 324 IFS-GGFFASHSTASSWVGSYSNIAKIQATSLYLFFYYLGSSVFGTFGGFFWFHMQWLGI 382
Query: 344 SLALLSVPLAYLVSAVIIGLDLRKTSYK 371
S+ ++++ L V + L++ ++K
Sbjct: 383 SVFIITM----LFFGVFLSFKLKQKNFK 406
>gb|AAA16158.1| (M80252) norA1199 protein [Staphylococcus aureus]
>gi|153055|gb|AAA26658.1| (M97169) norA [Staphylococcus
aureus]
Length = 388
Score = 77.6 bits (188), Expect = 2e-13
Identities = 85/366 (23%), Positives = 167/366 (45%), Gaps = 41/366 (11%)
Query: 1 MEKLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPA 60
M K I+++ ++ IF + +P L P+ +KDLG+ +++GLL+ + L +I
Sbjct: 1 MNKQILVLYFNIFLIF-LGIGLVIPVL-PVYLKDLGLTGSDLGLLVAAFALSQMIISPFG 58
Query: 61 GYIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISE 120
G + DK+G+K ++ I ++ +S+S + + +++ L+ R + G AG+ T LI++
Sbjct: 59 GTLADKLGKKLIICIGLILFSVSEFMFAIGQNFLILMLSRVIGGMSAGMVMPGVTGLIAD 118
Query: 121 LF-RERKGSALGF--------FMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIV 171
+ +K G+ F++GP IG + V+ + + +A L I++ I+
Sbjct: 119 ISPSHQKAKNFGYMSAIINSGFILGPGIGG-----FMAEVSHRMPFYFAG-ALGILAFIM 172
Query: 172 GILLM-----VAIKG----EPIKVEGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYL 222
I+L+ V+ G EP + + +K+ +L+L GL AF L S
Sbjct: 173 SIVLIHDPKKVSTNGFQKLEPQLLTKINWKVFITPVILTLVLSFGLSAF----ETLYSLY 228
Query: 223 VSRGVGMEKASLMFSMLSLVGILGSIIAGFLYD----HLGKVSVLLAYALNSLLTFLVIV 278
+ V + ++ GI G++ + +D + +++ + + S++ +++V
Sbjct: 229 TADKVNYSPKDISIAITG-GGIFGALFQIYFFDKFMKYFSELTFIAWSLIYSVIVLVLLV 287
Query: 279 IPSPLFLIPLGLVLYSVGGIM-----TAYTSEKASRENLGVVMGFVNMVGFFGATIGPYI 333
I + I + + +G M T Y S A + G G + G IGP I
Sbjct: 288 IADGYWTIMVISFVVFIGFDMIRPAITNYFSNIAG-DRQGFAGGLNSTFTSMGNFIGPLI 346
Query: 334 VGFLID 339
G L D
Sbjct: 347 AGALFD 352
>sp|Q46916|GUDP_ECOLI PROBABLE GLUCARATE TRANSPORTER (D-GLUCARATE PERMEASE)
>gi|7442470|pir||A65061 hypothetical protein b2789 -
Escherichia coli >gi|882684|gb|AAB40439.1| (U29581)
ORF_f450 [Escherichia coli] >gi|1789152|gb|AAC75831.1|
(AE000362) putative transport protein [Escherichia coli
K12]
Length = 450
Score = 77.6 bits (188), Expect = 2e-13
Identities = 86/427 (20%), Positives = 184/427 (42%), Gaps = 63/427 (14%)
Query: 6 ILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGD 65
I++++ + FNY R + + KD+G++ +G + ++ Y + Q+P G++ D
Sbjct: 21 IVVMLFIVTSFNYGDRATLSIAGSEMAKDIGLDPVGMGYVFSAFSWAYVIGQIPGGWLLD 80
Query: 66 KIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALY--GFFAGLYYAPA----TALIS 119
+ G K++ SI +S+ + L + + AL+ F GL AP+ + +++
Sbjct: 81 RFGSKRVYFWSIFIWSMFTLLQGFVDIFSGFGIIVALFTLRFLVGLAEAPSFPGNSRIVA 140
Query: 120 ELF-RERKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVA 178
F + +G+A+ F + I I+ + + W + F + + ++ + +
Sbjct: 141 AWFPAQERGTAVSIFNSAQYFATVIFAPIMGWLTHEVGWSHVFFFMGGLGIVISFIWLKV 200
Query: 179 IKGEPIKVEGV----------------------KFKIPRGVFLLSLANFLG----LGAF- 211
I EP + GV K K+P V + LG +G +
Sbjct: 201 IH-EPNQHPGVNKKELEYIAAGGALINMDQQNTKVKVPFSVKWGQIKQLLGSRMMIGVYI 259
Query: 212 ---------FAMLTFLVSYLV-SRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHL---- 257
+ +T+ YLV +RG+ + KA + S+ ++ G +G ++ G + D L
Sbjct: 260 GQYCINALTYFFITWFPVYLVQARGMSILKAGFVASVPAVCGFIGGVLGGIISDWLMRRT 319
Query: 258 ------GKVSVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLY--SVGGIMTAYTSEKASR 309
K +++ L+ ++ F V + + + L + +G + A ++ A +
Sbjct: 320 GSLNIARKTPIVMGMLLSMVMVFCNYVNVEWMIIGFMALAFFGKGIGALGWAVMADTAPK 379
Query: 310 ENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLG-YSLALLSVPLAYLVSA----VIIGLD 364
E G+ G NM G + P +G+++ G ++ AL+ V + L++ V++G D
Sbjct: 380 EISGLSGGLFNMFGNISGIVTPIAIGYIVGTTGSFNGALIYVGVHALIAVLSYLVLVG-D 438
Query: 365 LRKTSYK 371
+++ K
Sbjct: 439 IKRIELK 445
>pir||A64668 chloramphenicol resistance protein homolog HP1185 - Helicobacter
pylori (strain 26695) >gi|2314345|gb|AAD08231.1|
(AE000624) conserved hypothetical integral membrane
protein [Helicobacter pylori 26695]
Length = 391
Score = 77.3 bits (187), Expect = 3e-13
Identities = 67/297 (22%), Positives = 136/297 (45%), Gaps = 22/297 (7%)
Query: 14 WIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLL 73
+IFN + + V L+ I K + +A +GL++T+ SL +P + KI RK+LL
Sbjct: 24 FIFNTTEFVPVALLSDIA-KSFEMESATVGLMITAYAWVVSLGSLPLMLLSAKIERKRLL 82
Query: 74 TISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELF-RERKGSALGF 132
+ LS L L ++W L+ R F ++++ +L+ + R +K ALG
Sbjct: 83 LFLFALFILSHILSALAWNFWVLLLSRMGIAFAHSIFWSITASLVIRVAPRNKKQQALGL 142
Query: 133 FMVGPAIGSGITPLIVVP----VALTLSWRYAFLVLSIMSSIVGILLMVAIKGEPIKVEG 188
A+GS + ++ +P + L WR F V+ +++++ +L+ + P + G
Sbjct: 143 L----ALGSSLAMILGLPLGRIIGQILDWRSTFGVIGGVATLIALLMWKLLPHLPSRNAG 198
Query: 189 VKFKIP--------RGVFLLSLANFLGLGAFFAMLTFLVSYLVS-RGVGMEKASLMFSML 239
+P G++LL + + + F +++ +++ + +LM +
Sbjct: 199 TLASVPVLMKRPLLMGIYLLVI---MVISGHFTTYSYIEPFIIQISQFSPDITTLMLFVF 255
Query: 240 SLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSVG 296
L G++GS + G LY + + A L L+ V + +++ L + L+ +G
Sbjct: 256 GLAGVVGSFLFGRLYAKNSRKFIAFAMVLVICPQLLLFVFKNLEWVVFLQIFLWGIG 312
>emb|CAC13963.1| (AJ012115) multidrug efflux transporter [Listeria monocytogenes]
Length = 392
Score = 77.3 bits (187), Expect = 3e-13
Identities = 82/364 (22%), Positives = 153/364 (41%), Gaps = 21/364 (5%)
Query: 24 VPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSLS 83
V L P I + +G +++++ +L T+ + +++ +P G + K+G KL+ I + ++
Sbjct: 22 VDPLLPSIAESIGASHSQVEMLFTAYIFTMAIMMIPIGIVAGKMGYIKLIVIGLFIVTIF 81
Query: 84 SALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRERKGSALGFFMVGPAIGSGI 143
+ L L+ L RA +GF ++ A A ++ L R R G A+G + +
Sbjct: 82 ALLCGLSDTIGALSIFRAGWGFGNSMFMATAMTMLIALSRPR-GHAIGIYEASMGLEMAF 140
Query: 144 TPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKGEPIKV-----EGVKFKIPRGVF 198
PL+ + +SWRY + + I +L++ +K EP KV E + I + +
Sbjct: 141 GPLL-GGILGNISWRYPCFATACLIFIAFLLILFKVK-EPKKVAPAPREKNEVAIKQMLH 198
Query: 199 LLSLANFLGLG--------AFFAMLTF--LVSYLVSRGVGMEKASLMFSMLSLV--GILG 246
L FL + FF +L + LV +L+S L + LV +
Sbjct: 199 LFKYRPFLQIAFSGMFYYYCFFTILAYSPLVPWLISNSNWFCIFCLGIMLWHLVQRKVSH 258
Query: 247 SIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSVGGIMTAYTSEK 306
++ F + K S+L + +LL F+ ++ GL+L + T E
Sbjct: 259 ALEIRFNSKQILKGSLLACAVILALLGFIDNTAVDIGLIVISGLILGINNALFTTTVMEH 318
Query: 307 ASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVIIGLDLR 366
+ V G N V + GA P G L + LG + + + L ++ + L+
Sbjct: 319 SPYAR-SVTSGAYNFVRWLGAAFAPLCSGLLSEALGMKMPFIVASIICLAGMGLLFIKLK 377
Query: 367 KTSY 370
+
Sbjct: 378 PAHF 381
>gb|AAG34371.1|AF197465_3 (AF197465) putative nitrate/nitrite transporter; NarD [Pseudomonas
fluorescens]
Length = 421
Score = 77.3 bits (187), Expect = 3e-13
Identities = 86/370 (23%), Positives = 155/370 (41%), Gaps = 34/370 (9%)
Query: 5 IILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIG 64
++L + +L + + M L I + L +N + GLL + +L SL+++P G +
Sbjct: 9 LVLGMSTLAFTVCFMVWMMFAVLGVPIKELLALNETQFGLLAATPVLTGSLVRLPLGLLT 68
Query: 65 DKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELF-R 123
D+ G + + + +L L LI L YW + V L+ AG ++ A +++ F +
Sbjct: 69 DRFGGRIVFFLLMLACVLPLYLITLATAYWQFL-VLGLFVGLAGGSFSVGIAYVAKWFDK 127
Query: 124 ERKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGIL--LMVAIKG 181
+ +G A+G F G A G+ +T + + +W V S + I +L + A K
Sbjct: 128 QNQGFAMGVFGAGNA-GAAVTKFLAPALIAFGTWHLVPKVFSAILFITALLFWFLTAEKK 186
Query: 182 EPIKVEG------VKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYLVSR-GVGMEKASL 234
E G +K V+ + G + A+ ++ Y V G ++ A+L
Sbjct: 187 EHRNAGGATLREQLKSLKDPAVWRYCQYYSIVFGGYVALALWMTKYYVQEYGFSLQSAAL 246
Query: 235 MFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIPL--GLVL 292
+ + SL G + + G++ D G SV S + ++ P + G+V
Sbjct: 247 LAACFSLPGGVLRAVGGWMSDRWGAQSVTWWVLWVSWICLFLLSYPQTQLQVQTVNGIVD 306
Query: 293 YSVGGIMT-----------AYTSEKAS---------RENLGVVMGFVNMVGFFGATIGPY 332
+ +G T A+ KAS +N+G V G V + G G + P
Sbjct: 307 FHIGLNATLFPVILFVMGIAFAFGKASVFKYIANNYPQNMGAVSGIVGLAGGLGGFVLPI 366
Query: 333 IVGFLIDRLG 342
+ G L+D G
Sbjct: 367 MFGALVDLTG 376
>dbj|BAA36484.1| (AB019536) NorA [Staphylococcus aureus]
Length = 388
Score = 76.9 bits (186), Expect = 4e-13
Identities = 84/366 (22%), Positives = 167/366 (44%), Gaps = 41/366 (11%)
Query: 1 MEKLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPA 60
M K I ++ ++ IF + +P L P+ +KDLG+ +++GLL+ + L +I
Sbjct: 1 MNKQIFVLYFNIFLIF-LGIGLVIPVL-PVYLKDLGLTGSDLGLLVAAFALSQMIISPFG 58
Query: 61 GYIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISE 120
G + DK+G+K ++ I ++ +S+S + + ++ L+ R + G AG+ T LI++
Sbjct: 59 GTLADKLGKKLIICIGLILFSVSEFMFAVGHNFSVLMLSRVIGGMSAGMVMPGVTGLIAD 118
Query: 121 LF-RERKGSALGF--------FMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIV 171
+ +K G+ F++GP IG + V+ + + +A L I++ I+
Sbjct: 119 VSPSHQKAKNFGYMSAIINSGFILGPGIGG-----FMAEVSHRMPFYFAG-ALGILAFIM 172
Query: 172 GILLMVAIKG---------EPIKVEGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYL 222
++L+ K EP + + +K+ +L+L GL AF + + SY
Sbjct: 173 SVVLIHDPKKSTTSGFQKLEPQLLTKINWKVFITPAILTLVLAFGLSAFETLYSLYTSYK 232
Query: 223 VSRGVGMEKASLMFSMLSLVGILGSIIAGFLYD----HLGKVSVLLAYALNSLLTFLVIV 278
V+ + S+ ++ GI G++ + +D + +++ + + S++ +++V
Sbjct: 233 VN--YSPKDISI---AITGGGIFGALFQIYFFDKFMKYFSELTFIAWSLIYSVIVLVLLV 287
Query: 279 IPSPLFLIPLGLVLYSVGGIM-----TAYTSEKASRENLGVVMGFVNMVGFFGATIGPYI 333
I + I + + +G M T Y S A + G G + G IGP I
Sbjct: 288 IADGYWTIMVISFVVFIGFDMIRPAITNYFSNIAG-DRQGFAGGLNSTFTSMGNFIGPLI 346
Query: 334 VGFLID 339
G L D
Sbjct: 347 AGALFD 352
>emb|CAB76354.1| (AL158061) putative transmembrane transport protein. [Streptomyces
coelicolor A3(2)]
Length = 422
Score = 76.9 bits (186), Expect = 4e-13
Identities = 74/336 (22%), Positives = 158/336 (47%), Gaps = 26/336 (7%)
Query: 26 SLAPIIMKD--LGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSLS 83
++ P ++K LG+ + + T L+ ++ V G + D++GR++LL S++ +S+
Sbjct: 42 AIIPTLLKTHHLGMTAGDATTIATLSLVGVAIGAVCVGPLADRLGRRRLLIGSVVLFSVL 101
Query: 84 SALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISE-LFRERKGSALGFFMVGPAIGSG 142
+ ++ L +R L G G + +++E + R+ A M G G+
Sbjct: 102 TVVVPLANSVAMFAALRLLAGLGLGACMPVSLTMMAEHMPASRRARASTLTMTGYHTGAV 161
Query: 143 ITPLIVVPVALTLSWRYAFLVLSIMSSIVGIL----LMVAIKGEPIKVEGVKFKIP---- 194
IT L+ + V T +W F +L ++ ++ + L + E + +G + ++P
Sbjct: 162 ITSLLALQV--TDNWEILFYLLGVVGLVIAAIQWFKLPESAAFERARRDGAQ-RVPFTEL 218
Query: 195 ------RGVFLLSLANFLGLGAFFAMLTFLVSYLVSRGVGMEKASLMFSMLSLVGILGSI 248
R + +A+F+GL + + T+L + G + A +L++ G++G +
Sbjct: 219 LKPAYLRAGIGIWVASFMGLLLVYGLNTWLPKLMNDAGYPVPTAVTQLLVLNIGGVVGLV 278
Query: 249 IAGFLYDHLG-KVSVLLAYALNSL-LTFLVIVIPSPLFLIPL----GLVLYSVGGIMTAY 302
+ G++ D G K + ++ +A++ L L L + + S L L + G+ ++S ++ AY
Sbjct: 279 LGGYVADRRGIKGTTMVWFAVSVLMLGCLSVKMASDLLLNVVVFFTGVFVFSAMVLVYAY 338
Query: 303 TSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLI 338
+ G +G + +G G+ +GP I G L+
Sbjct: 339 VTHFYPASVRGTALGSASGIGRIGSIVGPSITGALV 374
>gb|AAK42961.1| Proline/betaine transporter, putative [Sulfolobus solfataricus]
Length = 446
Score = 76.5 bits (185), Expect = 5e-13
Identities = 98/414 (23%), Positives = 182/414 (43%), Gaps = 69/414 (16%)
Query: 12 LGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPA-------GYIG 64
+G++ + + S+AP++ K + + A + +++L YSL + G +G
Sbjct: 19 IGFLLDSYDLTMILSIAPVLAKVI-LPPASPLIATFNIILSYSLTIIFRPLGSAIFGNLG 77
Query: 65 DKIGRKKLLTISILGYSLSSALIVLTRDYWD--------LVTVRALYGFFAGLYYAPATA 116
DKIGR+ L I++LG ++SAL Y V +R G FAG Y+
Sbjct: 78 DKIGRRADLIITVLGLGITSALTSALPTYAQAGILSFVLFVLIRVAVGIFAGGEYSAGHP 137
Query: 117 LISELFRER-----KGSALGFFMVGPAIGSGITPLIV----VPVALTLSWRYAFLVLSIM 167
E + G G F G A+ + I + + V +WRY FL +++
Sbjct: 138 FAMEWTPYKWRGFISGLVQGGFSFGAALAAVIEGIFIGIYGVSGVEEFAWRYVFLT-AVI 196
Query: 168 SSIVGILLMVAIKGEPIKVEGVK-------------FKIP-RGVFLLSLANFLGLGAF-F 212
+ + + + +A+K P+ E VK FK P R FL +A G+ F +
Sbjct: 197 PAFIALAVRLAMKETPV-FEDVKKKNLIRRTPLADLFKAPYRRDFLQVMAYMTGMFFFAY 255
Query: 213 AMLTFLVSYL--VSRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNS 270
A+ F+ + L + +A+ ++S+ + G++I G L ++G+ + + + S
Sbjct: 256 ALFAFVPTILEHSPSTFSLGEANYIYSIGTYAAFAGALIFGTLSQYVGRRRLTIIW---S 312
Query: 271 LLTFLVIV---------------IPSPLFLIPLGLVLYSVGGIMTAYTSE--KASRENLG 313
++TF++ + I + LF I +G++ GI+ Y SE KAS G
Sbjct: 313 IITFVIAIPIYYGLITAAIAGNAITAMLFSIIIGIITQGPWGIIPIYLSERFKASMRASG 372
Query: 314 VVMGF---VNMVGFFGATIGPYIVGFLIDRLGY-SLALLSVPLAYLVSAVIIGL 363
V G+ + + G+F + P + +L L + S + ++ A+I+G+
Sbjct: 373 VGFGYSSGIFLGGWFSIYV-PLMHNYLFKSLDTPNNVWFSTAVLLMIGALIVGI 425
>gi|11498744 multidrug resistance protein [Archaeoglobus fulgidus]
>gi|7483888|pir||G69392 multidrug resistance protein
homolog - Archaeoglobus fulgidus
>gi|2649446|gb|AAB90102.1| (AE001025) multidrug
resistance protein [Archaeoglobus fulgidus]
Length = 451
Score = 76.5 bits (185), Expect = 5e-13
Identities = 82/344 (23%), Positives = 140/344 (39%), Gaps = 31/344 (9%)
Query: 29 PIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSLSSALIV 88
P I K+ I+ +G + T+ LL + VP G I D GRKK+ + +L +SL S L
Sbjct: 30 PAIGKEFQIDAITLGWIATAYLLAAGMFSVPFGRIADIAGRKKVFVVGLLVFSLGSILSA 89
Query: 89 LTRDYWDLVTVRALYGFFAGLYYAPATALISELF-RERKGSALGFFMVGPAIGSGITPLI 147
+ + L+ R L G + +A + A+++ +F + +G A+G G + P+
Sbjct: 90 IPPNAEMLIAFRVLQGVGGAMIFATSVAILTSVFPPQERGKAIGINTGAVYTGLSLGPIG 149
Query: 148 VVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKGEPIKVEGVKFKIPRGVFLLSLANFLG 207
+ L WR F+ + I+ V ++GE G KF + ++ FL
Sbjct: 150 GGFLTQNLGWRSLFIANGALGFFALIVASVYLRGEWADARGEKFDLAGSAIYAAMLFFLI 209
Query: 208 LG------AFFAMLTFLVSYLVSR---------GVGMEKASLMFSMLSLVGIL---GSII 249
G AF + L V V + ++L FS+ SL +L +
Sbjct: 210 YGFSEFSVAFIVLGAILALIFVVYENRQEHPVFAVRLLLSNLTFSLSSLAALLNYAATFA 269
Query: 250 AGFLYDHLGKVSVLLAYALN-SLLTFLVIVIPSPLFLIPLGLVLYSVGGIMTAYTSEKAS 308
GFL +S+ L Y T +I++ P + + + G I +
Sbjct: 270 VGFL------MSLYLQYVKGFDAQTAGLILVSQP---VVMAIFAPIAGWISDRIEPRVVA 320
Query: 309 RENLGV-VMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVP 351
+ V + + G G T I+ +L+ LG+ +AL S P
Sbjct: 321 STGMAVTTLSLILFAGINGETALSNIITYLM-LLGFGIALFSSP 363
>emb|CAA07482.1| (AJ007367) multi-drug resistance efflux pump [Streptococcus
pneumoniae]
Length = 399
Score = 76.5 bits (185), Expect = 5e-13
Identities = 91/384 (23%), Positives = 162/384 (41%), Gaps = 43/384 (11%)
Query: 10 ISLGWIFNY----SHRMAVPSLAPIIMKDLGINNAEI----GLLMTSLLLPYSLIQVPAG 61
+ + W N+ S + VP + PI +++LG+ + ++ GL ++ + +L G
Sbjct: 10 LRIAWFGNFLTGASISLVVPFM-PIFVENLGVGSQQVAFYAGLAISVSAISAALFSPIWG 68
Query: 62 YIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALI-SE 120
+ DK GRK ++ + L +++ + + + L+ +R L G FAG + ATALI S+
Sbjct: 69 ILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYWLIFLRLLNGVFAG-FVPNATALIASQ 127
Query: 121 LFRERKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIK 180
+ +E+ GSALG G G+ P I +A R FL++ + IL + IK
Sbjct: 128 VPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAELFGIRTVFLLVGSFLFLAAILTICFIK 187
Query: 181 GE----------PIKVEGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYLVSRG---- 226
+ P K K P + L L +F+ + ++ L Y+ G
Sbjct: 188 EDFQPVAKEKAIPTKELFTSVKYPYLLLNLFLTSFVIQFSAQSIGPILALYVRDLGQTEN 247
Query: 227 ----VGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIV-IPS 281
G+ +S+ FS + G++G L D +G +L+ S++ +L+ S
Sbjct: 248 LLFVSGLIVSSMGFSSMMSAGVMGK-----LGDKVGNHRLLVVAQFYSVIIYLLCANASS 302
Query: 282 PL------FLIPLGLVLYSVGGIMTAYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVG 335
PL FL LG G + A S+ + + V F + + G +GP
Sbjct: 303 PLQLGLYRFLFGLGTGALIPG--VNALLSKMTPKAGISRVFAFNQVFFYLGGVVGPMAGS 360
Query: 336 FLIDRLGYSLALLSVPLAYLVSAV 359
+ + GY + L S +
Sbjct: 361 AVAGQFGYHAVFYATSLCVAFSCL 384
>emb|CAB61680.1| (AL133213) putative transmembrane transport protein. [Streptomyces
coelicolor A3(2)]
Length = 440
Score = 76.5 bits (185), Expect = 5e-13
Identities = 88/361 (24%), Positives = 155/361 (42%), Gaps = 34/361 (9%)
Query: 36 GINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSLSSALIVLTRDYWD 95
G+++ + GLL T L+ ++ AG + D++GR + L ++++ Y++ + +Y
Sbjct: 72 GLDSGQTGLLTTVTLVVSAIGGALAGVLADRVGRVRALLLTVITYAVFTVACGFAPNYET 131
Query: 96 LVTVRALYGFFAGLYYAPATALISELFRE-RKGSALG----FFMVGPAIGSGITPLIVVP 150
L+ RAL G G +A L++E +G LG + VG A+ + L+
Sbjct: 132 LLVFRALQGLGFGGEWAVGAILVAEYASPGHRGRTLGAIQSSWAVGWALAVVVYTLVFSL 191
Query: 151 VALTLSWRYAFLVLSIMSSIVGILLMVAIKGEPIKVEGVKFKIPRGVF------------ 198
L+WR F ++ + +V + + +++ P E + RG F
Sbjct: 192 AGDDLAWRVMFWTGALPALLV-VWVRRSVQDAPRAAEAREKGTGRGSFAAIFKPGTADSP 250
Query: 199 -LLSLANFLGL------GAFFAMLTFLVSYLV-SRGVGMEKASLMFSMLSLVGILGSIIA 250
LL + F L G ++ + T++ +YL R + + + L LG +
Sbjct: 251 GLLRVTLFASLLSTGVQGGYYTLATWVPTYLKDERDLSVVGTGGYLTFLISGAFLGYLTG 310
Query: 251 GFLYDHLGKVSVLLAYALNSLLTFLVIV-IP---SPLFLI---PLGLVLYSVGGIMTAYT 303
G L D LG+ + +AL S + L IP L L+ PLG + ++ +Y
Sbjct: 311 GVLTDVLGRRRNIWLFALLSAVCILAYANIPRGADTLLLVLGFPLGFCMSAIFSGFGSYL 370
Query: 304 SEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAV-IIG 362
SE G GF G + P VGFL D G AL+ + Y ++A+ ++G
Sbjct: 371 SELYPTAVRGAGQGFTYNTGRAVGAVFPTTVGFLADSWGVGGALVFGAIGYGIAALALLG 430
Query: 363 L 363
L
Sbjct: 431 L 431
>pir||F69814 fosmidmycin resistance protein homolog yfnC - Bacillus subtilis
>gi|2116761|dbj|BAA20112.1| (D86418) YfnC [Bacillus
subtilis] >gi|2633045|emb|CAB12551.1| (Z99107) similar
to fosmidmycin resistance protein [Bacillus subtilis]
>gi|2633056|emb|CAB12561.1| (Z99108) similar to
fosmidmycin resistance protein [Bacillus subtilis]
Length = 409
Score = 76.1 bits (184), Expect = 6e-13
Identities = 78/377 (20%), Positives = 157/377 (40%), Gaps = 45/377 (11%)
Query: 6 ILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGD 65
ILI+I + + N S + +P++ PI+ + + + ++G++ +L + S++Q G+ D
Sbjct: 22 ILIIIGICHMLNDSLQAVIPAMFPILERSMSLTFTQLGIIAFTLNMVSSVMQPVVGWYTD 81
Query: 66 KIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRER 125
K R L + + L + + ++ G + +++ + + +
Sbjct: 82 KRPRPYALPVGLTASMLGILGLAFAPSFITILCCVFFIGLGSAIFHPEGSRVAYMAAGTK 141
Query: 126 KGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIK----- 180
+G A + VG G + PLI + + L ++ + ++++++ + LM K
Sbjct: 142 RGLAQSIYQVGGNSGQAMAPLITALILVPLG-QFGAVWFTLVAALAVMFLMYIAKWYASR 200
Query: 181 -GEPIKVEGVKFKIPRG--------------VFLL--------SLANFLGLGAFFAMLTF 217
G + G + K +FL+ ++ NF F+AM T+
Sbjct: 201 LGSLAQKSGKQKKTAENTAITKSVVSALIIIIFLIFARSWYTSAIGNFY---TFYAMDTY 257
Query: 218 LVSYLVSRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVI 277
VS +++A + L G +G+ + G L D GK V+L L S +V+
Sbjct: 258 HVS--------IQQAQSYIFVFLLFGAIGTFLGGPLADRFGKRFVILGSLLCSAPLAIVL 309
Query: 278 VIPSPLF----LIPLGLVLYSVGGIMTAYTSEKASRENLGVVMGFVNMVGFFGATIGPYI 333
P+ L +GLVL S + Y E + +G + G + F IG
Sbjct: 310 PFAGPVLAYGVLALIGLVLMSSFSVTVVYAQELVPGK-IGTMSGLTVGLAFGMGAIGAVA 368
Query: 334 VGFLIDRLGYSLALLSV 350
+G LID G + ++++
Sbjct: 369 LGALIDAAGLTPTMIAI 385
>gb|AAB31949.1| (S74031) NorA {ISP794, quinolone resistance} [Staphylococcus
aureus, NCTC 8325, Peptide Insertion, 388 aa]
Length = 388
Score = 76.1 bits (184), Expect = 6e-13
Identities = 86/366 (23%), Positives = 163/366 (44%), Gaps = 41/366 (11%)
Query: 1 MEKLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPA 60
M K I ++ ++ IF + +P L P+ +KDLG+ +++GLL+ + L +I
Sbjct: 1 MNKQIFVLYFNIFLIF-LGIGLVIPVL-PVYLKDLGLTGSDLGLLVAAFALSQMIISPFG 58
Query: 61 GYIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISE 120
G + DK+G+K ++ I ++ +S+S + + ++ L+ R + G AG+ T LI++
Sbjct: 59 GTLADKLGKKLIICIGLILFSVSEFMFAVGHNFSVLMLSRVIGGMSAGMVMPGVTGLIAD 118
Query: 121 LF-RERKGSALGF--------FMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIV 171
+ +K G+ F++GP IG + V+ + + +A L I++ I+
Sbjct: 119 ISPSHQKAKNFGYMSAIINSGFILGPGIGG-----FMAEVSHRMPFYFAG-ALGILAFIM 172
Query: 172 GILLMVAIKG---------EPIKVEGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYL 222
I+L+ K EP + + +K+ +L+L GL AF L S
Sbjct: 173 SIVLIHDPKKSTTSGFQKLEPQLLTKINWKVFITPVILTLVLSFGLSAF----ETLYSLY 228
Query: 223 VSRGVGMEKASLMFSMLSLVGILGSIIAGFLYD----HLGKVSVLLAYALNSLLTFLVIV 278
+ V + ++ GI G++ + +D + +++ + L S++ +++V
Sbjct: 229 TADKVNYSPKDISIAITG-GGIFGALFQIYFFDKFMKYFSELTFIAWSLLYSVVVLILLV 287
Query: 279 IPSPLFLIPLGLVLYSVGGIM-----TAYTSEKASRENLGVVMGFVNMVGFFGATIGPYI 333
+ + I L + +G M T Y S A E G G + G IGP I
Sbjct: 288 FANDYWSIMLISFVVFIGFDMIRPAITNYFSNIAG-ERQGFAGGLNSTFTSMGNFIGPLI 346
Query: 334 VGFLID 339
G L D
Sbjct: 347 AGALFD 352
>sp|P21191|NORA_STAAU QUINOLONE RESISTANCE NORA PROTEIN >gi|97835|pir||A37838 norA
protein - Staphylococcus aureus
>gi|216975|dbj|BAA14147.1| (D90119) ORF for norA
[Staphylococcus aureus]
Length = 388
Score = 75.7 bits (183), Expect = 8e-13
Identities = 86/366 (23%), Positives = 163/366 (44%), Gaps = 41/366 (11%)
Query: 1 MEKLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPA 60
M K I ++ ++ IF + +P L P+ +KDLG+ +++GLL+ + L +I
Sbjct: 1 MNKQIFVLYFNIFLIF-LGIGLVIPVL-PVYLKDLGLTGSDLGLLVAAFALSQMIISPFG 58
Query: 61 GYIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISE 120
G + DK+G+K ++ I ++ +S+S + + ++ L+ R + G AG+ T LI++
Sbjct: 59 GTLADKLGKKLIICIGLILFSVSEFMFAVGHNFSVLMLSRVIGGMSAGMVMPGVTGLIAD 118
Query: 121 LF-RERKGSALGF--------FMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIV 171
+ +K G+ F++GP IG + V+ + + +A L I++ I+
Sbjct: 119 ISPSHQKAKNFGYMSAIINSGFILGPGIGG-----FMAEVSHRMPFYFAG-ALGILAFIM 172
Query: 172 GILLMVAIKG---------EPIKVEGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYL 222
I+L+ K EP + + +K+ +L+L GL AF L S
Sbjct: 173 SIVLIHDPKKSTTSGFQKLEPQLLTKINWKVFITPVILTLVLSFGLSAF----ETLYSLY 228
Query: 223 VSRGVGMEKASLMFSMLSLVGILGSIIAGFLYD----HLGKVSVLLAYALNSLLTFLVIV 278
+ V + ++ GI G++ + +D + +++ + L S++ +++V
Sbjct: 229 TADKVNYSPKDISIAITG-GGIFGALFQIYFFDKFMKYFSELTFIAWSLLYSVVVLILLV 287
Query: 279 IPSPLFLIPLGLVLYSVGGIM-----TAYTSEKASRENLGVVMGFVNMVGFFGATIGPYI 333
+ + I L + +G M T Y S A E G G + G IGP I
Sbjct: 288 FANGYWSIMLISFVVFIGFDMIRPAITNYFSNIAG-ERQGFAGGLNSTFTSMGNFIGPLI 346
Query: 334 VGFLID 339
G L D
Sbjct: 347 AGALFD 352
>pir||D83117 probable MFS transporter PA4233 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9950449|gb|AAG07621.1|AE004840_7
(AE004840) probable MFS transporter [Pseudomonas
aeruginosa]
Length = 462
Score = 75.7 bits (183), Expect = 8e-13
Identities = 83/358 (23%), Positives = 155/358 (43%), Gaps = 45/358 (12%)
Query: 22 MAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYS 81
M +P LA G A IGL + + L +++Q+P G I D+IGR+ ++ + +L ++
Sbjct: 33 MVLPVLATYGQDLAGATPALIGLAIGAYGLTQAILQIPFGTISDRIGRRPVIVVGLLIFA 92
Query: 82 LSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRERKGSALGFFMVGPAIG- 140
+AL W ++ R L G AG A AL+S+L RE+ + M+G +IG
Sbjct: 93 AGAALAANADSIWGVIAGRVLQG--AGAISAAVMALLSDLTREQHRTK-AMAMIGMSIGV 149
Query: 141 SGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKGEPIKV-------------- 186
S +++ PV L + + ++VG+LL++ +P +
Sbjct: 150 SFAVAMVLGPVLTHLFGLHGLFWFTAGMALVGLLLILFFVPQPDHMTQHRESSVARQALL 209
Query: 187 ----EGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYLVSRGVGMEKASLMFSMLSLV 242
G ++ G+ +L + + + +F A+ LV G+ E+ ++ LV
Sbjct: 210 PTLKHGDLLRLDAGILIL---HAILMASFVALPLALVH---EGGLPKEQHWWVYLTALLV 263
Query: 243 GILGSIIAGFLYDHLGKVSVLLAYALNSLLT--FLVIVIPSPLFLIPLGLVLYSVGGIMT 300
G G + + ++ +L A+ +LL +V L ++ +G V++ T
Sbjct: 264 GFFGMVPFIIYAEKKRRMKRVLTGAVATLLACELFFLVFGHSLAMLVVGTVVF-----FT 318
Query: 301 AYTSEKASRENL----------GVVMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALL 348
A+ +AS +L G MG + F GA +G + G++ G S+ +
Sbjct: 319 AFNLLEASLPSLVSKVSPAGGKGTAMGVYSTSQFLGAALGGILGGWMFQHGGLSMVFI 376
>pir||B82991 glycerol-3-phosphate transporter PA5235 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9951544|gb|AAG08620.1|AE004936_3 (AE004936)
glycerol-3-phosphate transporter [Pseudomonas
aeruginosa]
Length = 448
Score = 75.7 bits (183), Expect = 8e-13
Identities = 83/407 (20%), Positives = 174/407 (42%), Gaps = 52/407 (12%)
Query: 10 ISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGR 69
I +G+ Y R P +++D G + ++G+ M+++ + Y L + G + D+
Sbjct: 34 IFIGYAGYYLLRKNFSLAMPYLIED-GYSRGQLGVAMSAIAIAYGLSKFIMGLVSDRSNP 92
Query: 70 KKLLTISILGYSLSSALIVLTRDYWDLVTVRALY------GFFAGLYYAPA-TALISELF 122
+ L +L ++ + + +W +V ++ G+ G+ + P+ ++
Sbjct: 93 RVFLPFGLL--VSAAVMFIFGFAHWATSSVAIMFVLLFINGWAQGMGWPPSGRTMVHWWS 150
Query: 123 RERKGSALGFFMVGPAIGSG-ITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKG 181
++ +GS + + V +G G I PL ++ +AL WR AF V +I++ V + A++
Sbjct: 151 QKERGSVVSVWNVAHNVGGGLIGPLFLLGLALFGDWRSAFYVPAIVAVGVAVFAYFAMRD 210
Query: 182 EPIK-----VEGVKFKIPRG------------------------VFLLSLANFLGLGAFF 212
P +E K P G ++ ++LAN +
Sbjct: 211 TPQSCGLPPIEKHKDDYPEGYDEHHERELSTKEIFVTYVLRNKLLWYIALANVFVYLLRY 270
Query: 213 AMLTFLVSYL-VSRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVS------VLLA 265
+L + +YL ++ ++K+S + GI G+++ G+L D L K + V +
Sbjct: 271 GVLDWAPTYLKEAKHFNVDKSSWAYFFYEWAGIPGTLLCGWLSDKLFKGNRGATGVVFMI 330
Query: 266 YALNSLLTFLVIVIPSPLF----LIPLGLVLYSVGGIMTAYTSEKASRENLGVVMGFVNM 321
L + + +P LI +G ++Y ++ E A ++ G GF +
Sbjct: 331 LVTVGTLIYWLNPAGNPAIDMAALIMIGFLIYGPVMLIGLQALELAPKKAAGTAAGFTGL 390
Query: 322 VGFFGATIGP-YIVGFLIDRLGYSLALLSVPLAYLVSAVIIGLDLRK 367
G+ G ++ +VG+ +D G+ + A L++ + + L LRK
Sbjct: 391 FGYLGGSVAANALVGYTVDHFGWDGGFKLLIGACLLAILFLCLTLRK 437
>sp|P42237|GUDP_BACSU PROBABLE GLUCARATE TRANSPORTER (D-GLUCARATE PERMEASE)
>gi|7428803|pir||H69752 probalble glucarate transporter
- Bacillus subtilis >gi|709999|dbj|BAA06469.1| (D30808)
glucarate dehydratase [Bacillus subtilis]
>gi|2632534|emb|CAB12042.1| (Z99105) similar to
glucarate transporter [Bacillus subtilis]
Length = 455
Score = 74.5 bits (180), Expect = 2e-12
Identities = 87/408 (21%), Positives = 168/408 (40%), Gaps = 53/408 (12%)
Query: 6 ILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGD 65
I+ ++ L NY+ R + + DLG+++ +G + ++ Y + Q+P G++ D
Sbjct: 21 IVFMLFLVTSINYADRATLSITGDSVQHDLGLDSVAMGYVFSAFGWAYVIGQLPGGWLLD 80
Query: 66 KIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYG--FFAGLYYAPA-----TALI 118
+ G K ++ +SI +S + L + + L+ F GL AP+ +
Sbjct: 81 RFGSKTIIALSIFFWSFFTLLQGAIGFFSAGTAIILLFALRFLVGLSEAPSFPGNGRVVA 140
Query: 119 SELFRERKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVA 178
S +G+A FF I P ++ + + W F+V+ I ++ ++ +
Sbjct: 141 SWFPSSERGTASAFFNSAQYFAIVIFPPLMGWLTHSFGWHSVFVVMGIAGILLAVIWLKT 200
Query: 179 I---KGEPIKVEGVKFKIPRGVFLLS--------------------LANFLGLGAFFA-- 213
+ K P E I +G L+S L N + +G + A
Sbjct: 201 VYEPKKHPKVNEAELAYIEQGGGLISMDDSKSKQETESKWPYIKQLLTNRMLIGVYIAQY 260
Query: 214 --------MLTFLVSYLV-SRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLL 264
LT+ YLV +RG+ + +A + S+ +L G G ++ G + D L K L
Sbjct: 261 CITTLTYFFLTWFPVYLVQARGMSILEAGFVASLPALCGFAGGVLGGIVSDILLKKGRSL 320
Query: 265 AYA------LNSLLTFLVIVI----PSPLFLIPLGLVLY--SVGGIMTAYTSEKASRENL 312
+A LL+ +IV + L ++ + L + G + A S+ + +E
Sbjct: 321 TFARKVPIIAGMLLSCSMIVCNYTDSAWLVVVIMSLAFFGKGFGALGWAVVSDTSPKECA 380
Query: 313 GVVMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVI 360
G+ G N G + P I+G++++ G L A ++A++
Sbjct: 381 GLSGGLFNTFGNIASITTPIIIGYIVNATGSFNGALVFVGANAIAAIL 428
>pir||F83233 probable MFS transporter PA3303 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9949431|gb|AAG06691.1|AE004752_7
(AE004752) probable MFS transporter [Pseudomonas
aeruginosa]
Length = 391
Score = 74.5 bits (180), Expect = 2e-12
Identities = 88/371 (23%), Positives = 168/371 (44%), Gaps = 17/371 (4%)
Query: 7 LILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDK 66
L+L+SL + + P + +DL ++ + G L T L ++L G++ +
Sbjct: 5 LLLLSLTTFAAGLAESILIGILPPLAEDLRVSISLAGQLTTLFSLGFALAAPLLGWLTRR 64
Query: 67 IGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRE-R 125
I R++LL ++L ++LS+AL L Y L+ R GL A+ L +EL +
Sbjct: 65 IERRRLLLATLLLFALSNALAALAPGYLGLLLARLGMSACCGLLIVLASLLAAELAAPAQ 124
Query: 126 KGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIK----G 181
+G A+G +G + + V ++ WR+ F +++ S + +LL + G
Sbjct: 125 RGRAIGLIFMGISGSLVFGVPLGVQISDWFGWRWIFAGIAVYSLPLCLLLWRYLPQRQAG 184
Query: 182 EPIKVEGVKFKIPR-GVFLLSLANFLGLGAFFAMLTFLVSYLVSR-GV-GMEKASLMFSM 238
+ EG ++ + ++L L + L LG F + + YL S G+ + SL+ +
Sbjct: 185 DLPGREGYLRQLRQPALWLAQLVSILLLGGHFTLFAYFTPYLASMAGIRSPSEISLILLL 244
Query: 239 LSLVGILGSIIAGFLYDHLG-KVSVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSVGG 297
+ L + G I G+L DHLG + ++ L A +L V + + +P+ +V ++
Sbjct: 245 IGLAALSGGYIGGWLADHLGHRRALRLVPAAFALALAAVPLSLGSIGFLPVLMVWSAISW 304
Query: 298 IMTAYTSEKASRE-----NLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPL 352
+++ R + GV + M G +G + G ++ LG + A V L
Sbjct: 305 MISPVVQSFLLRSDPASGSAGVALNTSAM--HLGVGLGAALGGLVVAALGVA-ATPWVGL 361
Query: 353 AYLVSAVIIGL 363
A +++A+ L
Sbjct: 362 ALVLAALACAL 372
>pir||H71846 hypothetical protein jhp1111 - Helicobacter pylori (strain J99)
>gi|4155710|gb|AAD06692.1| (AE001539) putative
[Helicobacter pylori J99]
Length = 391
Score = 74.1 bits (179), Expect = 2e-12
Identities = 67/297 (22%), Positives = 135/297 (44%), Gaps = 22/297 (7%)
Query: 14 WIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLL 73
+IFN + + V L+ I K + +A +GL++T+ SL +P + KI RK+LL
Sbjct: 24 FIFNTTEFVPVALLSDIA-KSFEMESATVGLMITAYAWVVSLGSLPLMLLSAKIERKRLL 82
Query: 74 TISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELF-RERKGSALGF 132
+ S L L ++W L+ R F ++++ +L+ + R +K ALG
Sbjct: 83 LFLFALFIFSHILSALAWNFWVLLLSRMGIAFAHSIFWSITASLVIRVAPRNKKQQALGL 142
Query: 133 FMVGPAIGSGITPLIVVP----VALTLSWRYAFLVLSIMSSIVGILLMVAIKGEPIKVEG 188
A+GS + ++ +P + L WR F V+ +++++ +L+ + P + G
Sbjct: 143 L----ALGSSLAMILGLPLGRIIGQILDWRSTFGVIGGVATLIMLLMWKLLPHLPSRNAG 198
Query: 189 VKFKIP--------RGVFLLSLANFLGLGAFFAMLTFLVSYLVS-RGVGMEKASLMFSML 239
+P G++LL + + + F +++ +++ + +LM +
Sbjct: 199 TLASVPILMKRPLLVGIYLLVI---MVISGHFTTYSYIEPFIIQISQFSPDITTLMLFVF 255
Query: 240 SLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSVG 296
L G++GS + G LY + + A L L+ V + ++I L + L+ +G
Sbjct: 256 GLAGVVGSFLFGRLYAKNSRKFIAFAMVLVICPQLLLFVFKNLEWVIFLQIFLWGIG 312
>gb|AAG23889.1| (AY008833) TcaB [Staphylococcus aureus]
Length = 402
Score = 74.1 bits (179), Expect = 2e-12
Identities = 88/362 (24%), Positives = 162/362 (44%), Gaps = 41/362 (11%)
Query: 4 LIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYI 63
+ I+IL SL I S M +P L P I D + L ++ ++ + + AG I
Sbjct: 13 IFIIILGSLTAIGALSIDMFLPGL-PDIRHDFQTTTSNAQLTLSMFMIGLAFGNLFAGPI 71
Query: 64 GDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFR 123
D GR+K L I+++ ++L+S IV + W +V +R L G G + A+ S+++
Sbjct: 72 SDSTGRRKPLIIAMIIFTLASLGIVFVHNIWLMVALRFLQGVTGGAAAVISRAIASDMY- 130
Query: 124 ERKGSALGFFMVGPAIGSGITPLI---VVPVALTLS-WRYAFLVLSIMS--SIVGILLMV 177
G+ L FM + +GI P++ + + L S WR F++L+I ++G LL V
Sbjct: 131 --SGNELTKFMALLMLVNGIAPVVAPTIGGIILNYSVWRMVFVILTIFGFVMVIGSLLKV 188
Query: 178 AIKGEPIKV------EGVKFKIPRGVFLLSLANF----LGLGAFFAMLTFLVS---YLVS 224
E + V G+K LL F L G F +L +S +++
Sbjct: 189 P---ESLTVTNRESSSGLKTMFKNFKILLKTPRFVLPMLIQGMTFVILFTYISASPFIIQ 245
Query: 225 RGVGME--KASLMFSMLSLVGILGSIIAGFLYDHLGKVSVL----LAYALNSLLTFLVIV 278
+ GM + S MF+ + + I+ S + G+L D + ++ + + +L +V++
Sbjct: 246 KIYGMTAIQFSWMFAGIGITLIISSQLTGYLVDFIDSQKLMRGMTMIQIIGVILVTIVLL 305
Query: 279 IPSPLFLIPLGLVLY--SVGGIMT-----AYTSEKASRENLGVVMGFVNMVGFFGATIGP 331
+++ +G ++ V G+ T A + R + ++G V + FG P
Sbjct: 306 NHWNFWILAIGFIILIAPVTGVATLGFTIAMDESSSGRGSSSSLLGLVQFL--FGGVASP 363
Query: 332 YI 333
+
Sbjct: 364 LV 365
>gb|AAK42828.1| Permease [Sulfolobus solfataricus]
Length = 419
Score = 73.4 bits (177), Expect = 4e-12
Identities = 91/410 (22%), Positives = 169/410 (41%), Gaps = 61/410 (14%)
Query: 5 IILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIG 64
I+LI+ +L I +Y R + + P++ + I++ E G++ Y ++ GY
Sbjct: 9 IVLIIFAL-IIVDYIDRGLINTALPVLKSEFHISSFEAGIIGDGFTFGYLIMNPLVGYFL 67
Query: 65 DKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRE 124
DK G K++ + + + A+ V + + R L G + + T +++ R+
Sbjct: 68 DKYGPKRVFSRFAILWGAVQAINVFAFSTFYFIVTRVLLGIGEAVGFPGVTKIVANWLRK 127
Query: 125 RKGSALGFFMVGPAIGSGIT-------PLIVVPVALTLSWRYAFLVLSIMSSIVGIL--- 174
+ A G + + GI L + L+WR FLV +++ I+ I+
Sbjct: 128 DE-KARGGTISDSGVNLGIVFGSLFMLGLFAIIPNQELAWRLGFLVSGLLAIILAIILGR 186
Query: 175 LMVAIKGEPIKVE--------------GVKFKIPRGVFLLSLANFLG--------LGAFF 212
L+ + + K+ GVK K+P +L S N+ G G FF
Sbjct: 187 LLYDLPEQHPKISKEELDYILSGREKVGVKTKLPLSYWLRS-KNYWGYMQGLGAQAGIFF 245
Query: 213 AMLTFLVSYL-----VSRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYA 267
+ T+L YL +S +E +L++S G +G ++ G++ D L K + L +
Sbjct: 246 GLFTWLPLYLFYARHLSLSFTLEYTALIWSF----GFIGELVGGYVVDKLIKRNPNLGFK 301
Query: 268 LNSLLTFLVI--------VIPSPLFLIPLGLVLYSV---GGIMTAYTSEKASRENLGVVM 316
+ ++ L + +I SP+ + + +V + GI A S S E G
Sbjct: 302 VGFAVSSLAVTIGLAAATLISSPIEAVEILMVTFFFLRWSGIQWAAPSFLVSTELAGQFG 361
Query: 317 GFVNMVGFFGATIGPYIVGFLID-----RLGYSLALLSVPLAYLVSAVII 361
G + I P + G ++ LG + L+ + L Y + VII
Sbjct: 362 GHIGFWETLWGIIVPIVFGATVEVTKAYLLGMEI-LIGIGLIYFIGTVII 410
>sp|O34691|YCEI_BACSU HYPOTHETICAL METABOLITE TRANSPORT PROTEIN IN RAPJ-OPUAA INTERGENIC
REGION >gi|7475934|pir||C69757 transporter homolog yceI
- Bacillus subtilis >gi|2415746|dbj|BAA22256.1|
(AB000617) YceI [Bacillus subtilis]
>gi|2632581|emb|CAB12089.1| (Z99105) similar to
transporter [Bacillus subtilis]
Length = 400
Score = 73.4 bits (177), Expect = 4e-12
Identities = 91/398 (22%), Positives = 176/398 (43%), Gaps = 47/398 (11%)
Query: 6 ILILISLGWIFN------YSHRMAVP----SLAPIIMKDLGINNAEIGLLMTSLLLPYSL 55
+L + LGW+F+ S +A +L+P MK +G N+ IG+ + L
Sbjct: 12 LLGVAGLGWLFDAMDVGILSFIIAALHVEWNLSPEEMKWIGSVNS-IGMAAGAFLF---- 66
Query: 56 IQVPAGYIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPAT 115
G + D+IGRKK+ I++L +S+ S + + +R + G G A+
Sbjct: 67 -----GLLADRIGRKKVFIITLLCFSIGSGISAFVTSLSAFLILRFVIGMGLGGELPVAS 121
Query: 116 ALISE-LFRERKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGIL 174
L+SE + E++G + A+G LI V + W+ A L+L+ +++ +
Sbjct: 122 TLVSEAVVPEKRGRVIVLLESFWAVGWLAAALISYFVIPSFGWQ-AALLLTALTAFYALY 180
Query: 175 LMVAIKGEPIKVEGVKFK---------------IPRGVFLLSLANFLGLGAFFAMLTFLV 219
L ++ P K E + K R +LS+ F + +++ M +L
Sbjct: 181 LRTSLPDSP-KYESLSAKKRSMWENVKSVWARQYIRPTVMLSIVWFCVVFSYYGMFLWLP 239
Query: 220 SYLVSRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSL-LTFLVIV 278
S ++ +G M ++ +++L + G A +L + G+ +L+ Y + + +
Sbjct: 240 SVMLLKGFSMIQSFEYVLLMTLAQLPGYFSAAWLIEKAGRKWILVVYLIGTAGSAYFFGT 299
Query: 279 IPSPLFLIPLGLVL--YSVG--GIMTAYTSEKASRENLGVVMGFVNMVGFFGATIGPYIV 334
S L+ G++L +++G G++ AYT E+ G G G GP +V
Sbjct: 300 ADSLSLLLTAGVLLSFFNLGAWGVLYAYTPEQYPTAIRATGSGTTAAFGRIGGIFGPLLV 359
Query: 335 GFLIDR-LGYSLALLSVPLAYLVSA---VIIGLDLRKT 368
G L R + +S+ +A L++ +I+G + ++T
Sbjct: 360 GTLAARHISFSVIFSIFCIAILLAVACILIMGKETKQT 397
>sp|Q43975|PCAK_ACICA 4-HYDROXYBENZOATE TRANSPORTER >gi|3172116|gb|AAC37151.1| (L05770)
putative transport protein [Acinetobacter sp. ADP1]
Length = 457
Score = 73.4 bits (177), Expect = 4e-12
Identities = 84/395 (21%), Positives = 164/395 (41%), Gaps = 57/395 (14%)
Query: 23 AVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSL 82
A+ +AP + +D G++ +++G +M++ L + + +G D+ GRK +L++S+L +
Sbjct: 54 AMGFIAPALAQDWGVDRSQLGPVMSAALGGMIIGALVSGPTADRFGRKIVLSMSMLVFGG 113
Query: 83 SSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRERKGSALGFFM-----VGP 137
+ + + LV R L G G AT L SE R S L M +G
Sbjct: 114 FTLACAYSTNLDSLVIFRFLTGIGLGAAMPNATTLFSEYCPARIRSLLVTCMFCGYNLGM 173
Query: 138 AIGSGITPLIVVPVA-----LTLSWRYAFLVLSIMSSIVGILLMVAIKGE---------- 182
AIG I+ ++ L W L+L ++ + + +KG+
Sbjct: 174 AIGGFISSWLIPAFGWHSLFLLGGWAPLILMLLVIFFLPESYRFLIVKGKNTKKVRQILS 233
Query: 183 ---PIKVEGV-KFKIP----------------------RGVFLLSLANFLGLGAFFAMLT 216
P KV+GV +F +P +G LL + F+GL + + +
Sbjct: 234 RIAPQKVQGVTEFHVPEEKVEAGTKKGVFGMLFSAKYVKGTVLLWVTYFMGLVMIYLLTS 293
Query: 217 FLVSYLVSRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLV 276
+L + + G +E+A+ + + G+L ++ G+ D ++ + L + + F V
Sbjct: 294 WLPTLMRETGASLERAAFLGGLFQFGGVLSALFIGWAMDRFNPNRIIAGFYLAAGI-FAV 352
Query: 277 IVIPS-------PLFLIPLGLVLYSVGGIMTAYTSEKASRENLGVVMGFVNMVGFFGATI 329
IV S LF++ G+ + M ++ + + +++ +G FGA
Sbjct: 353 IVGQSLSNPTLLALFILCAGIAVNGAQSSMPVLSARFYPTQCRATGVAWMSGIGRFGAVF 412
Query: 330 GPYIVGFLIDR---LGYSLALLSVPLAYLVSAVII 361
G +I L+ L++L +P A+ +
Sbjct: 413 GAWIGAVLLGNNWSFTMILSMLIIPARAAAIAIFV 447
>pir||S56583 hypothetical protein f261b - Escherichia coli
>gi|537199|gb|AAA97254.1| (U14003) ORF_f261b
[Escherichia coli]
Length = 261
Score = 73.0 bits (176), Expect = 5e-12
Identities = 41/168 (24%), Positives = 82/168 (48%), Gaps = 1/168 (0%)
Query: 7 LILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDK 66
++L+ + NY R ++ I ++LG++ EIG L++ L Y + Q+P G + D+
Sbjct: 44 MLLLFFAAVINYLDRSSLSVANLTIREELGLSATEIGALLSVFSLAYGIAQLPCGPLLDR 103
Query: 67 IGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFR-ER 125
G + +L + + +SL A+ + ++ V VR G +I++ F +
Sbjct: 104 KGPRLMLGLGMFFWSLFQAMSGMVHNFTQFVLVRIGMGIGEAPMNPCGVKVINDWFNIKE 163
Query: 126 KGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGI 173
+G +GFF IG ++P I+ + L + WR F+ + ++ + I
Sbjct: 164 RGRPMGFFNAASTIGVAVSPPILAAMMLVMGWRGMFITIGVLGIFLAI 211
>pir||E69783 bicyclomycin resistance protein homolog ydgK - Bacillus subtilis
>gi|1881374|dbj|BAA19401.1| (AB001488) SIMILAR TO
BICYCLOMYCIN RESISTANCE PROTEIN. [Bacillus subtilis]
>gi|2632881|emb|CAB12387.1| (Z99107) similar to
bicyclomycin resistance protein [Bacillus subtilis]
Length = 402
Score = 73.0 bits (176), Expect = 5e-12
Identities = 88/366 (24%), Positives = 160/366 (43%), Gaps = 37/366 (10%)
Query: 22 MAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYS 81
M +PS P I KDL + + + L +T+ L+ ++ Q+ G + D GR+K L I I ++
Sbjct: 30 MYLPSF-PEIAKDLSASASLVQLSLTACLVGLTIGQLIVGPVSDAQGRRKPLLICIFLFA 88
Query: 82 LSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRERKGSA-LGFFMVGPAIG 140
LSS L+ + LV R L GF A + A++ ++F R+ S MV A+
Sbjct: 89 LSSLFCALSPNITTLVAARFLQGFTASAGLVLSRAIVRDVFTGRELSKFFSLLMVITAVA 148
Query: 141 SGITP-----LIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIK-------------GE 182
+ P ++++P A +W F VL I+ ++ +L+ + +K G
Sbjct: 149 PMVAPMTGGAILLLPFA---TWHTIFHVLMIIGFLLVLLIALRLKETLPLEKRIPSSIGT 205
Query: 183 PIKVEGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYLVSRGVGMEKASLMFSMLSLV 242
+K G K + F+ G+F + Y GV + S++F + L
Sbjct: 206 SVKTMGSLLKDRSFMGYALTVGFIHGGSFAYVSGTPFVYQDIYGVSPQVFSILFGINGLA 265
Query: 243 GILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVI----VIPSPLFLIPLGLVLYSVGGI 298
I GS I G + + S+L + +++ V+ +I PL + + + +Y +
Sbjct: 266 IISGSFIIGRFGGIIHEKSLLRIAVITAMIATAVLLTMTMIHGPLATLVISIFIYMITIG 325
Query: 299 MTAYTSEKASRENLGVVMGFVNMVGFFGATIG--PYIVGFLIDRLGYSLALLSVPLAYL- 355
M ++ + E G + G A +G P ++G ++ L +VP+ +
Sbjct: 326 MVLTSTFTLAMEKQG------HRAGSASALLGMLPLLLGSIVSPLVGINETTAVPMGAIM 379
Query: 356 -VSAVI 360
V+AVI
Sbjct: 380 FVTAVI 385
>dbj|BAB04893.1| (AP001511) multidrug-efflux transporter [Bacillus halodurans]
Length = 399
Score = 73.0 bits (176), Expect = 5e-12
Identities = 78/369 (21%), Positives = 158/369 (42%), Gaps = 48/369 (13%)
Query: 3 KLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGY 62
K ++++++++ ++ + +P L P ++ G ++ E+GLL+ L+ G
Sbjct: 7 KPLLMLMVNM-FVVMMGIGLVIPIL-PYYIEAFGASSVELGLLIAIFSFMQFLLAPFWGR 64
Query: 63 IGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISE-L 121
+ DK+GRK L+ + + G++++ + +W L R L G F A A +S+
Sbjct: 65 LSDKVGRKPLIAVGMFGFAVAEFIFAFATQFWMLFVSRILAGAFGSAVMPAAMAYVSDRT 124
Query: 122 FRERKGSALGF--------FMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGI 173
E++G +G +VGP IG + + L + +F + + S++ +
Sbjct: 125 SEEKRGHGMGLLGASMALGIVVGPGIGGWLAEFSLATPFLFAGFAASF---AAIFSLLWL 181
Query: 174 LLMVAIKGEPIKVEGVK--------FKIPRGVFL-------LSLANFLGLGAFFAMLTFL 218
+ ++ +VE V + P G L LANF + FA+ F
Sbjct: 182 PESLPLEKRKTEVEPVNQFVQMWQAVRSPIGFLLFLVFGLSFGLANFQTIFGIFALHRFH 241
Query: 219 VSYLVSRGVGMEKASLMFSMLSLVGILGSI----IAGFLYDHLGKVSVLLAYALNSLLTF 274
+ S + ++ L GI+G+I + G L + G+ V+L S + F
Sbjct: 242 YN-----------PSEVGFIMVLTGIVGAIAQGSLVGRLTERYGEEKVVLGSLSLSGIGF 290
Query: 275 LVIVIPSPLFLIPLGLVLYSVGG--IMTAYTS--EKASRENLGVVMGFVNMVGFFGATIG 330
L++++ + + L+ +G + A S K + + G++MG N + G +G
Sbjct: 291 LIMMLAFNYWTVIATTCLFFLGNSILRPAVQSFLSKMAGDQQGMIMGLNNSILSLGNVVG 350
Query: 331 PYIVGFLID 339
+ G L +
Sbjct: 351 ALLAGLLFE 359
>gb|AAK41760.1| Transport protein [Sulfolobus solfataricus]
Length = 430
Score = 72.6 bits (175), Expect = 7e-12
Identities = 102/415 (24%), Positives = 175/415 (41%), Gaps = 63/415 (15%)
Query: 12 LGWIFNYSHRMAVPSLAPIIMK-----DLGINNAEIGLLMTSLLLPYSLIQVPAG----- 61
LGW+ + +A +A I K +GI +GL+ T + P G
Sbjct: 18 LGWLMDGYTSIAYALVAVTISKIFFPSTIGI----LGLIATFGGFAVGALARPVGSLVFG 73
Query: 62 -YIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALY--------GFFAGLYYA 112
+IGDKIGRK +L ++ILG+SL ++ L Y + L+ G FAG Y
Sbjct: 74 NFIGDKIGRKNMLVLTILGFSLIASSKALLPSYETAGILAPLFLYIILFAEGMFAGAEYG 133
Query: 113 PATALISELFRERKGSALGFFMVGPAIGSGITPLIVVPVAL----------TLSWRYAFL 162
T L E K +G F V G+G + +V AL TL WR F
Sbjct: 134 GGTTLALESVPVGKRGFIGSF-VQSGFGTGYFVISLVYSALYSMFGNEGFQTLGWRVLF- 191
Query: 163 VLSIMSSIVGILLMVAIKGEPI----KVEGVKFKIP-RGVFLLSLANFL-GL----GAFF 212
I+ ++ +++ PI K KIP + +F +S ++ L GL G +
Sbjct: 192 ATCILPGLITLIIRKMTDESPIFKDMKSGNEVVKIPIKELFKMSYSSVLIGLMITSGLLY 251
Query: 213 ---AMLTFLVSYLVSRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHL--GKVSVLLAYA 267
A +F + L +G+ L ++++LV + G GFL D + G+ +L Y+
Sbjct: 252 INTATFSFYPTVLTIQGIPGTIVGLSVAIINLVSLFGVWFGGFLADVIKRGRKVPMLIYS 311
Query: 268 LNSLLTFLVIVIPSPLFLIPLGLVLYS--------VGGIMTAYTSEKASRENLGVVMGFV 319
+ + T ++ L + L +++S + + A+ +E+ S++ +GF
Sbjct: 312 IIFIFTVYPVLYLGLLKNVYLSTIVFSLQAFLEAMIFSTLPAFLAEQFSKKYRTTGVGFT 371
Query: 320 NMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAV--IIGLDLRKTSYKG 372
G G G + + + Y L S + +++ + I+G+ L K +Y G
Sbjct: 372 YNGGAIG---GGFAISATLALSTYLGLLYSWSINIIIAGIIMIMGIVLAKETYTG 423
>gb|AAC45758.1| (U40014) nitrate transporter [Staphylococcus carnosus]
Length = 388
Score = 72.6 bits (175), Expect = 7e-12
Identities = 82/364 (22%), Positives = 164/364 (44%), Gaps = 45/364 (12%)
Query: 24 VPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSLS 83
+ L P+I +D+ I +++I +++ ++ S++++P GY+ + IG K + S + L
Sbjct: 27 IAPLMPMISQDIKITSSQISIVLAIPVILGSVLRIPFGYLTNIIGAKWVFFSSFI--ILL 84
Query: 84 SALIVLTRDYWDLVTVRALYGFFAG----LYYAPATALISELFRERKGSALGFFMVGPAI 139
+ +L++ V + L GFF G ++ T++ +++ G A G + +G +
Sbjct: 85 FPIFLLSQA--QSVNMLMLAGFFLGVGGAVFSVGVTSIPKYFPKDKVGLANGIYGMG-NL 141
Query: 140 GSGITPLIVVPVALTLSWRYAF-LVLSIMSSIVGILLMVAIKGEPIKVEGVKFKIP---- 194
G+ ++ + P+A + W+ L L +M+ ++ + EP K KIP
Sbjct: 142 GTAVSSFLAPPIAGAIGWQSTVRLYLIVMAVFAIVMFFLGDAKEP------KVKIPLVAQ 195
Query: 195 -------RGVFLLSLANFLGLGAFFAMLTFLVSYLVSR------GVGMEKASLMFSMLSL 241
+ LS F+ G+F A FL YLV G+ +A + ++ +
Sbjct: 196 TKDLLKDLRTYYLSFWYFITFGSFVAFGIFLPKYLVDHYELTTVDAGI-RAGIFIAIATF 254
Query: 242 VGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSV-----G 296
+ LG II D + V L L ++ +++ I + + L +G + SV
Sbjct: 255 LRPLGGIIG----DKIDAVKALKVDFLFMIIGAIILGIANDMILFTVGCLTVSVCAGIGN 310
Query: 297 GIMTAYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYS-LALLSVPLAYL 355
G++ + +E GV G V+M+G G P ++ ++ G S LA + + L +
Sbjct: 311 GLVFKLVPQYFQKE-AGVANGIVSMMGGLGGFFPPLVITYVTSITGTSHLAFIFLALFGV 369
Query: 356 VSAV 359
++ V
Sbjct: 370 LALV 373
>gi|11499136 conserved hypothetical protein [Archaeoglobus fulgidus]
>gi|7430263|pir||D69442 conserved hypothetical protein
AF1541 - Archaeoglobus fulgidus
>gi|2649020|gb|AAB89705.1| (AE000996) conserved
hypothetical protein [Archaeoglobus fulgidus]
Length = 372
Score = 71.8 bits (173), Expect = 1e-11
Identities = 86/375 (22%), Positives = 168/375 (43%), Gaps = 22/375 (5%)
Query: 1 MEKLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPA 60
M+ ++++ L+SL Y S+ + G+ A IGL+ +++ +
Sbjct: 5 MKFILLMGLVSLFGDITYE---GARSIVGPYLATFGLTAAAIGLITGFGEFAGYGLRLLS 61
Query: 61 GYIGDKIGRKKLLTISILGYSLSSALIVLT-RDYWDLVTVRALYGFFAGLYYAPAT-ALI 118
GYI D+ G LLT LGYSL A+ +L +YW + + + PA A++
Sbjct: 62 GYIADRTGNYWLLTF--LGYSLILAIPLLAFANYWWIAALLIVAERLGKAIRTPARDAML 119
Query: 119 SELFRE-RKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMV 177
S ++ +G+ G +G+ I PLIV +++ AF+ L + + +V + L
Sbjct: 120 SFATKQVGRGTGFGIHEAMDQVGAVIGPLIVFSALAGYTFKEAFIALFLPALLVILFLFA 179
Query: 178 AIKGEP----IKVEGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYLVSRGVGMEKAS 233
K P ++E + ++ +L SL FL + F + L+SY ++ V ++
Sbjct: 180 TWKLYPTPQRFEIEEQESRVEGSFWLYSLFVFLSVAGFLSFP--LLSYHLAGYVDLKLIP 237
Query: 234 LMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLI----PLG 289
L++++ + + ++I+G YD +G +++L L L+ L+ + PS + ++ G
Sbjct: 238 LLYALAMGIDAISALISGRCYDRIGLKTLMLVPLLTPLI--LLALHPSIIGVLVGVAAWG 295
Query: 290 LVLYSVGGIMTAYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYSLA--L 347
V+ I A ++ + G N V G ++G+L D L +
Sbjct: 296 AVMGMHEAITRAAVADLTGVKKRSTAYGVFNTVFGVAMLAGGAVLGYLYDISAALLVGFV 355
Query: 348 LSVPLAYLVSAVIIG 362
L V +A + +++G
Sbjct: 356 LVVEVAAFATLLMLG 370
>pir||E83385 hypothetical protein PA2091 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9948103|gb|AAG05479.1|AE004636_10
(AE004636) hypothetical protein [Pseudomonas aeruginosa]
Length = 427
Score = 71.8 bits (173), Expect = 1e-11
Identities = 80/355 (22%), Positives = 147/355 (40%), Gaps = 27/355 (7%)
Query: 31 IMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSLSSALIVLT 90
I DL + + L +T L L +L G++ D+ G + L+ +L A + L
Sbjct: 56 IAADLDWDRGQSALPVTLLGLAVALSSPLKGWLVDRWGARALVLPLTAALALCLASLALA 115
Query: 91 RDYWDLVTVRALYGFFAGLYYAPATALISELFRERKGSALGFFMVGPAIGSGITPLIVVP 150
R W L + AL G P ++ F R+G+A G +G +G + +
Sbjct: 116 RSGWQLYLLFALLGLLTP-GNIPYARILGGWFERRRGAAYGILGLGFGVGGPLALYLGSA 174
Query: 151 VALTLSWRYAFLVLSIMSSIVGILLMVAIKGE----------------PIKVEGVKFKIP 194
WR FLV ++ ++ + L+ A+ E P G ++
Sbjct: 175 CIDAFGWRATFLVYGLLEGLLALPLLYALFRERPGDLPQARRTPADALPGATPGQAWR-- 232
Query: 195 RGVFLLSLAN-FLGLGAFFAMLTFLVSYLVSRGVGMEKASLMFSMLSLVGILGSIIAGFL 253
F L + N LG+ A ++ V L RG+ E A+ + + L + I+ G+L
Sbjct: 233 SADFWLIVGNLILGVFAVTGVMVHGVPLLQERGLSREVATDVLAALWVGMIVSQPALGYL 292
Query: 254 YDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSVG-----GIMTAYTSEKAS 308
D + L +AL + L L++++ P L+ + L +G G + S
Sbjct: 293 LDRYDTPRIALPFALLAALGLLLLLLGGPPALLWGAVFLIGLGAGGETGTTQYFVSRYFG 352
Query: 309 RENLGVVMGFVNMVGF-FGATIGPYIVGFLIDRLG-YSLALLSVPLAYLVSAVII 361
+ V+ G + F ++G +++G+ DR G Y+ + L + A+ V+A ++
Sbjct: 353 LRHFSVIYGSIQPFTFAIAISLGSWLLGYFYDRAGSYAGSTLVLLGAFGVAAGLL 407
>dbj|BAB06030.1| (AP001515) unknown conserved protein [Bacillus halodurans]
Length = 391
Score = 71.8 bits (173), Expect = 1e-11
Identities = 91/387 (23%), Positives = 169/387 (43%), Gaps = 30/387 (7%)
Query: 7 LILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDK 66
+I S+ + +SH + +P L+P I + LG IGL+++S + ++P G + D
Sbjct: 11 VIFYSVSFFLWFSHFVYLPILSPYI-EFLGGKYVYIGLVLSSYGFMQFVCRLPIGIVSDL 69
Query: 67 IGRKKLLTISILGYSLSSALIVLTRDYWDLVTV-RALYGFFAGLYYAPATALISELFRER 125
+ R+K I +G S +S + ++ LV + RAL G A + T L S F +
Sbjct: 70 LKRRKPFIIFGMGTSAASCFLFALTEHLGLVLLARALAGVAAATWVV-FTVLFSSCFTDS 128
Query: 126 K----GSALGFFMV-GPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIK 180
+ S++ F +V +G ++ +V +L W F + ++S + L ++ +
Sbjct: 129 RVHEAMSSISFIVVLAQLLGMIVSGFLVD----SLGWHAPFWIGGLLSLLGATLALLIYE 184
Query: 181 -----GEPIKVEGVKFKIPRGVFLLSLANFLGLGA----FFAMLTFLVSYLVSRGVGMEK 231
G P+++ + I LL +FL + A F M FL +Y G+ +
Sbjct: 185 PNVKAGAPVQLGDLSSVIREP--LLLKVSFLSIIAHSIIFTTMFGFLPTYATRIGLNTQG 242
Query: 232 ASLMFSMLSLVGILGSIIAG-FLYDHLGKVSVL-LAYALNSLLTFLVIVIPS--PLFLIP 287
S + + +G++ G + LGK + L +A+ + T L +I + PL ++
Sbjct: 243 LSFIVFAFMIPHAIGTLFLGNVIVPRLGKWNALNVAFLGTVVFTLLTPMIDTKVPLMVVQ 302
Query: 288 --LGLVLYSVGGIMTAYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYSL 345
G L + ++ + E +RE MG + G GP++ G L LG ++
Sbjct: 303 GFNGFFLGILFPLLLGMSIESIAREKRATAMGVYQALYAVGMFTGPFLAGILSASLGLAV 362
Query: 346 AL-LSVPLAYLVSAVIIGLDLRKTSYK 371
LA L S ++ R+ Y+
Sbjct: 363 GFYFCAGLALLASILVFVWKRRRAVYR 389
>emb|CAC08554.1| (AL121673) bA305P22.2 (novel protein) [Homo sapiens]
Length = 456
Score = 71.8 bits (173), Expect = 1e-11
Identities = 84/375 (22%), Positives = 155/375 (40%), Gaps = 52/375 (13%)
Query: 12 LGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKK 71
LG Y R ++P + +D G N E G++++S Y L QV G++GD+IG +K
Sbjct: 52 LGTCLLYCARSSMPICTVSMSQDFGWNKKEAGIVLSSFFWGYCLTQVVGGHLGDRIGGEK 111
Query: 72 LLTISILGY----SLSSALIVLTRDYWDLVTV-RALYGFFAGLYYAPATALISELFRERK 126
++ +S + +++ L L+ + +T R L G G+Y+ T+L+S+ RE +
Sbjct: 112 VILLSASAWGSITAVTPLLAHLSSAHLAFMTFSRILMGLLQGVYFPALTSLLSQKVRESE 171
Query: 127 ----------GSALGFFMVGPAIGS------GITPLIVVPVALTLSWRYAFLVLSIMSSI 170
GS G + G A+GS G + LTL W + +
Sbjct: 172 RAFTYSIVGAGSQFGTLLTG-AVGSLLLEWYGWQSIFYFSGGLTLLWVWYVYRYLLSEKD 230
Query: 171 VGILLMVAIKGEPI----KVEGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYLVSRG 226
+ + L V + P+ +V + V+ ++ +FF +L++L ++
Sbjct: 231 LILALGVLAQSRPVSRHNRVPWRRLFRKPAVWAAVVSQLSAACSFFILLSWLPTFF--EE 288
Query: 227 VGMEKASLMFSMLS-LVGILGSIIAGFLYDHLGK------------------VSVLLAYA 267
+ +F+++ LV I S+ +GFL DHL +S + A
Sbjct: 289 TFPDAKGWIFNVVPWLVAIPASLFSGFLSDHLINQGYRAITVRKLMQGMGLGLSSVFALC 348
Query: 268 LNSLLTFLVIVIPSPLFLIPLGLVLYSVGGIMTAYTSEKASRENLGVVMGFVNMVGFFGA 327
L +F V+ +GL ++ GI + + + G + G N G
Sbjct: 349 LGHTSSFCESVV---FASASIGLQTFNHSGI--SVNIQDLAPSCAGFLFGVANTAGALAG 403
Query: 328 TIGPYIVGFLIDRLG 342
+G + G+L++ G
Sbjct: 404 VVGVCLGGYLMETTG 418
>sp|P44535|YDEA_HAEIN HYPOTHETICAL PROTEIN HI0135 >gi|1074278|pir||E64143 chloramphenicol
resistance protein homolog HI0135 - Haemophilus
influenzae (strain Rd KW20) >gi|1573088|gb|AAC21806.1|
(U32699) conserved hypothetical transmembrane protein
[Haemophilus influenzae Rd]
Length = 396
Score = 71.4 bits (172), Expect = 2e-11
Identities = 81/370 (21%), Positives = 159/370 (42%), Gaps = 42/370 (11%)
Query: 6 ILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGD 65
+LI+ G+IFN + + V L+ I + + A+ GL+MT ++ +PA
Sbjct: 15 VLIMACAGFIFNTTEFVPVAMLSDIA-QSFDMQTADTGLMMTVYAWTVLIMSLPAMLATG 73
Query: 66 KIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELF-RE 124
+ RK LL + + + L V+ ++W L+ R ++++ +L+ + +
Sbjct: 74 NMERKSLLIKLFIIFIVGHILSVIAWNFWILLLARMCIALAHSVFWSITASLVMRISPKH 133
Query: 125 RKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKGEPI 184
+K ALG +G A+ + + I V + WR F ++++++ + L++ + P
Sbjct: 134 KKTQALGMLAIGTALATILGLPIGRIVGQLVGWRVTFGIIAVLALSIMFLIIRLLPNLPS 193
Query: 185 KVEGVKFKIP----RGVFL-LSLANFLGLGAFFAMLTFLVSYLVSRG-VGMEKASLMFSM 238
K G +P R + L L + + + A F T++ +++ G + A+ + +
Sbjct: 194 KNAGSIASLPLLAKRPLLLWLYVTTAIVISAHFTAYTYIEPFMIDVGHLDPNFATAVLLV 253
Query: 239 LSLVGILGSIIAGFLYDHLGKVSV-----LLAYALNSLL--TFLVIVIPSPLFLIPLGL- 290
GI S++ LY + LL ++L LL T +I + S +F+ +G+
Sbjct: 254 FGFSGIAASLLFNRLYRFAPTKFIVVSMSLLMFSLLLLLFSTKTIIAMFSLVFIWGIGIS 313
Query: 291 ----------------------VLYSVGGIMTAYTSEKASRENLGVVMGFVNMVGFFGAT 328
+YS GI A A NL +N +G+ GA
Sbjct: 314 CIGLSLQMRVLKLAPDATDVATAIYS--GIFNAGIGAGALFGNLATTYLGLNEIGYTGAA 371
Query: 329 IGPYIVGFLI 338
+G ++GF+I
Sbjct: 372 LG--LIGFII 379
>gb|AAC15508.1| (L49465) hypothetical metabolite transport protein [Pseudomonas
fluorescens]
Length = 405
Score = 71.4 bits (172), Expect = 2e-11
Identities = 78/330 (23%), Positives = 137/330 (40%), Gaps = 38/330 (11%)
Query: 61 GYIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISE 120
G++ D+IGRKK+L ++L + + S Y L+ VR + G G AL +E
Sbjct: 66 GWVADRIGRKKILVGAVLLFGVFSLCTAYVESYSSLLLVRFMTGLGLGAALPNLIALCAE 125
Query: 121 LFRER-KGSALGFFMVGPAIG---------------------SGITPLIVVP-VALTLSW 157
ER +G+A+ G +G G+TPL+VVP +AL L
Sbjct: 126 AVSERHRGTAISVMYCGVPLGGALAAVVAMFSSEHWQTTFIIGGLTPLLVVPLMALLLPE 185
Query: 158 RYAFLVLSIMSSIVGILLMVAIKGEPIKVEGVKFKIPRGVFLLSLANFLGLGAFFAMLTF 217
AF + ++ A+ GE R L L+ F L + +L +
Sbjct: 186 STAFRQQHVTTASPRSSTAQALFGE---------GRARCTLALWLSYFFTLTVMYMLLNW 236
Query: 218 LVSYLVSRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLL---AYALNSL--L 272
L S L+ +G +A ++ + ++ G +GS++ G + D + V+L A L +L +
Sbjct: 237 LPSLLLEQGFTKPQAGMVQMLFNIGGAMGSLLGGVMLDRCNGLKVVLFVYAGVLAALAGV 296
Query: 273 TFLVIVIPSPLFLIPLGLVLYSVGGIMTAYTSEKASRENLGVVMGFVNMVGFFGATIGPY 332
V ++P + +GL + + ++ A +G +G G+ GP
Sbjct: 297 GLSVGIVPMAIAGFAVGLFVMAAQLVLYALAPPSYPTSVRATGVGAAVAIGRLGSVAGPL 356
Query: 333 IVG-FLIDRLGYSLALLSVPLAYLVSAVII 361
G L G + LL+ +++A+ I
Sbjct: 357 AAGQILAAGAGTTGVLLATSPGLVIAALSI 386
>pir||F71848 probable transporter - Helicobacter pylori (strain J99)
>gi|4155704|gb|AAD06687.1| (AE001538) putative
transporter [Helicobacter pylori J99]
Length = 443
Score = 71.4 bits (172), Expect = 2e-11
Identities = 80/350 (22%), Positives = 159/350 (44%), Gaps = 39/350 (11%)
Query: 42 IGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRA 101
+GL + L + Q P G + DKIGRK ++ + +L + + S + + D LV R
Sbjct: 41 VGLAVGGAYLTQIIFQTPMGILSDKIGRKVVVMVCLLLFLIGSLVCFVANDIITLVIGRF 100
Query: 102 LYGFFA--GLYYAPATALISELFRERKGSALGFFM-----VGPAIGSGITPLIVVPVALT 154
+ G A G+ A + E R + + +G F+ + AIG G+ VA
Sbjct: 101 IQGMGALGGVVSAMVADEVKEEERTKAMAIMGAFIFISFTISMAIGPGV-------VAFL 153
Query: 155 LSWRYAFLVLSIMSSIVGILLMVAIKGEP---IKVEGVKFKIP--RGVFLLSLANFLGLG 209
++ FL+ +I+ +++ +L+++ +K P +++ +K P + ++LL L++F
Sbjct: 154 GGAKWLFLLTAIL-TLLSLLMLLKVKDAPKISYQIKNIKAYQPNSKALYLLYLSSFFE-K 211
Query: 210 AFFAMLTFLVSYLVSRGVGMEKASLMFSML--SLVGILGSIIAGFLYDHLGK-VSVLLAY 266
F ++ L+ + +++ L+ + +L+G+L IA + + K V+L+
Sbjct: 212 MFMTLIFVLIPLALVNEFHKDESFLILVYVPGALLGVLSMGIASVMAEKYNKPKGVMLSG 271
Query: 267 ALNSLLTFLVIVIPSP------LFLIPLGLVLYSVG-----GIMTAYTSEKASRENLGVV 315
L ++++L + + L+L +G+ + +G IM + S+ A G V
Sbjct: 272 VLLFIVSYLCLFLADSSFLGKYLWLFIVGVAFFFIGFATLEPIMQSLASKFAKVHEKGKV 331
Query: 316 MGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVIIGLDL 365
+G G+ G+ +G G LG S + L + +I GL L
Sbjct: 332 LGQFTTFGYLGSFVGGVSGGLSYHHLGVS----NTSLIIVALGLIWGLSL 377
>pir||B83180 probable MFS transporter PA3718 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9949884|gb|AAG07105.1|AE004791_2
(AE004791) probable MFS transporter [Pseudomonas
aeruginosa]
Length = 413
Score = 71.4 bits (172), Expect = 2e-11
Identities = 82/350 (23%), Positives = 157/350 (44%), Gaps = 22/350 (6%)
Query: 29 PIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSLSSALIV 88
P + + G + A + +M++ + AG + + G ++LLT + +S L
Sbjct: 43 PSLQRSFGGDLAALSWIMSAFPFVGVFGGIAAGLLVRRWGDRRLLTGGLAILGGASLLGA 102
Query: 89 LTRDYWDLVTVRALYGFFAGLYYAPATALISELFRERKGSALGFFMVGPAIGSGITPLIV 148
+D+ L+ R + G + A A++ + E + S + F + +G L +
Sbjct: 103 SMQDFTWLLATRFVEGLGFLIVVVAAPAVLHRITSETRRSVV--FGLWSTFMAGGIALSM 160
Query: 149 VPVALTLSWRYAFLVLSIMSSIVGILLMVAIKGEP-IKVEGVK-------FKIPRGVFLL 200
+ L WR + + +++ + +LL +++ + + GV+ K+P + LL
Sbjct: 161 LFGPLLADWRADWQLSALLVLVAALLLPLSVPADDGCRAAGVRPAGLGTLLKVP-AITLL 219
Query: 201 SLANFLGLGAFFAMLTFLVSYLVSR-GVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGK 259
+L FFA++TFL +L+ R GV +E A L+ + + LG++ AGF+ +
Sbjct: 220 ALGFTTYNLQFFALMTFLPVFLMQRLGVALETAGLIGAAIVAANALGNVAAGFILSRGIR 279
Query: 260 VSVLLAY-ALNSLLT---FLVIVIPSPLFLIPLGLVLYSVGGIMTAYTSEKASRENLG-- 313
LLA A+ LT F +P L I LG V +V G++ A +
Sbjct: 280 PGALLASTAILMGLTGAAFFHAAMPG-LLAIALGFVFSAVAGMLPTTVLATAPLASPAPS 338
Query: 314 ---VVMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVI 360
+ +G+V + G IGP ++G ++ R +S A+ + +A AV+
Sbjct: 339 LTPLAIGWVMQGNYLGQVIGPLLIGLIVSRFDWSGAIGLMLVAGAAGAVL 388
>dbj|BAB07028.1| (AP001518) multidrug resistance protein [Bacillus halodurans]
Length = 403
Score = 71.4 bits (172), Expect = 2e-11
Identities = 84/385 (21%), Positives = 165/385 (42%), Gaps = 33/385 (8%)
Query: 6 ILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVP-AGYIG 64
++ L S+ + + M +P L PII ++L I++ ++ LL+T + ++I +P AGY+
Sbjct: 9 LMSLASIPLVMTLGNSMLIPVL-PIIERELDISSLQVSLLITVYSV-VAIIFIPIAGYLS 66
Query: 65 DKIGRKKLLTISIL-----GYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALIS 119
D IGRKK++ S++ G A Y ++ R L G A L+
Sbjct: 67 DIIGRKKVIIPSLILAAIGGVISGFAAWKSPSPYTMILVGRLLQGIGAAGAAPIVMPLVG 126
Query: 120 ELFRERK--GSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMV 177
+LF++ K LG G ++P++ +A T+ W F + + +L++
Sbjct: 127 DLFQQEKEVSRGLGIIETSNTFGKVLSPILGAYLA-TIVWYLPFWAIPLFCLFSILLMLF 185
Query: 178 AIKGEPIKVEGVKFKI------------PRGVFLLSLANFLGLGAFFAMLTFLVSYLVSR 225
+K E E V F+ R ++ + + + + F +L +L + L R
Sbjct: 186 LVKTEKETKEPVPFQTFIQTIKTIFKREGRWLYAVFVVGCICMFLLFGILFYLSTMLEER 245
Query: 226 G--VGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLV--IVIPS 281
G++K ++ L+ + I ++ + K+ + L +LLT I+
Sbjct: 246 YQIEGVKKGVVLAIPLAALCIASLATGRWIEEDKAKMKWMSVLGL-ALLTASTAWIIFSE 304
Query: 282 PLFLIPLGLVLYSVGGIMT-----AYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGF 336
++++ GL + +G MT A +E +E G + N + F G GP +
Sbjct: 305 SIYVLLAGLFISGIGIGMTLPSLDALVTEGIHKEQRGTITSLYNSMRFVGVAFGPPLFAL 364
Query: 337 LIDRLGYSLALLSVPLAYLVSAVII 361
L+ +++ A+L +I+
Sbjct: 365 LMKTSHSITFMVNAITAFLTMLLIL 389
>gb|AAB81315.1| (U89712) putative 3-(3-hydroxyphenyl) propionate transport protein;
HppK [Rhodococcus globerulus]
Length = 453
Score = 71.0 bits (171), Expect = 2e-11
Identities = 52/171 (30%), Positives = 86/171 (49%), Gaps = 4/171 (2%)
Query: 27 LAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSLSSAL 86
+AP + K I++ EIG L+++ ++ +L + + DKIGR++L ++G ++ AL
Sbjct: 40 VAPHLGKSWDISSVEIGYLLSAGIIGTALGAIFISPLADKIGRRRLAIWCLVGITVGMAL 99
Query: 87 IVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRE-RKGSALGFFMVGPAIGSGITP 145
+ L+ RA G G A L+SE + R+G+ALG + VG +G +
Sbjct: 100 SACAVNVPQLIAFRAFAGLGIGGLVANLNVLVSEFSSDKRRGTALGIYGVGYPLGGAVGG 159
Query: 146 LIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKGEPIKVEGVKFKIPRG 196
I + WR AF+ +I I I+L+V IK P +E + K P G
Sbjct: 160 AISGVLISVFDWRSAFIFGTI---ITAIMLVVVIKTLPESIEFLIEKRPVG 207
>pir||E64667 multidrug-efflux transporter - Helicobacter pylori (strain 26695)
>gi|2314341|gb|AAD08227.1| (AE000624) multidrug-efflux
transporter [Helicobacter pylori 26695]
Length = 443
Score = 71.0 bits (171), Expect = 2e-11
Identities = 81/350 (23%), Positives = 159/350 (45%), Gaps = 39/350 (11%)
Query: 42 IGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRA 101
+GL + L + Q P G + DKIGRK ++ + +L + S + + D LV R
Sbjct: 41 VGLAVGGAYLTQIVFQTPMGILSDKIGRKVVVMVCLLLFLAGSLVCFIANDIVWLVIGRF 100
Query: 102 LYGFFA--GLYYAPATALISELFRERKGSALGFFM-----VGPAIGSGITPLIVVPVALT 154
+ G A G+ A + E R + + +G F+ + AIG G+ VA
Sbjct: 101 IQGMGALGGVISAMVADEVKEEERTKAMAIMGAFIFISFTISMAIGPGV-------VAFL 153
Query: 155 LSWRYAFLVLSIMSSIVGILLMVAIKGEP---IKVEGVKFKIP--RGVFLLSLANFLGLG 209
++ FL+ +I+ +++ +L+++ +K P +++ +K P + ++LL L++F
Sbjct: 154 GGAKWLFLLTAIL-TLLSLLMLLKVKDAPKISYQIKNIKAYQPNSKALYLLYLSSFFE-K 211
Query: 210 AFFAMLTFLVSYLVSRGVGMEKASLMFSML--SLVGILGSIIAGFLYDHLGK-VSVLLAY 266
AF ++ L+ + +++ L+ + +L+G+L IA + + K V+L+
Sbjct: 212 AFMTLIFVLIPLALVNEFHKDESFLILVYVPGALLGVLSMGIASVMAEKYNKPKGVMLSG 271
Query: 267 ALNSLLTFLVIVIPSP------LFLIPLGLVLYSVG-----GIMTAYTSEKASRENLGVV 315
L ++++L + + L+L +G+ + +G IM + S+ A G V
Sbjct: 272 VLLFIVSYLCLFLADSSFLGKYLWLFIVGVAFFFIGFATLEPIMQSLASKFAKVHEKGKV 331
Query: 316 MGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVIIGLDL 365
+G G+ G+ +G G LG S + L + +I GL L
Sbjct: 332 LGQFTTFGYLGSFVGGVSGGLSYHHLGVS----NTSLIVVALGLIWGLSL 377
>emb|CAB93456.1| (AL357591) putative integral membrane transport protein
[Streptomyces coelicolor A3(2)]
Length = 462
Score = 71.0 bits (171), Expect = 2e-11
Identities = 87/349 (24%), Positives = 158/349 (44%), Gaps = 57/349 (16%)
Query: 61 GYIGDKIGRKKLLTISILGYSLSSALIVLTRDY-----WD---LVTVRALYGFFAGLYYA 112
G +GD++GR+K+L ++++ + + I L Y W L+ R + GF G YA
Sbjct: 98 GPLGDRVGRQKVLAVTMIMMAAGTFAIGLIPSYATIGVWAPVLLLAARLVQGFSTGGEYA 157
Query: 113 PATALISELFRERKGSALGFF-----MVGPAIGSGITPLIVVPVA----LTLSWRYAFLV 163
A+ I+E +++ LG + + G G+G+ L+ ++ ++ WR FL+
Sbjct: 158 GASTFIAEYAPDKRRGFLGSWLEFGTLAGYIGGAGLVTLMTALLSDGDLMSWGWRIPFLI 217
Query: 164 LSIMSSIVGILLMV------AIKGEPIKVEGVKFKIPRGVFLL----SLANFLGLGAFFA 213
M IVG+ L + A E K E + K+P + +L +GL F
Sbjct: 218 AGPM-GIVGLYLRMRLEETPAFAAEVAKAETARVKVPLREMVTGQWRALLLCVGLVLVFN 276
Query: 214 MLTF-LVSYLVSRGVGMEKASLMFSMLSLVGILGSII-----AGFLYDHLGKVSVLLAYA 267
+ + L+SY+ S K +L ++G++ ++ AG L D +G+ V+ A
Sbjct: 277 VTDYMLLSYMPSYLTSELKYDETHGLLVVLGVMTLMMVVQPFAGALTDRVGRRPVIAA-- 334
Query: 268 LNSLLTFLVIVIPSPLF-----LIPLGLVLYSVGGIMTAYTSEKAS--------RENLG- 313
FL++ +P+ L L+ + L + ++G ++ +T+ S R G
Sbjct: 335 --GCAGFLLLSVPALLLIREGSLLAVALGMGALGLLLVCFTASMPSALPALFPTRVRYGS 392
Query: 314 VVMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVIIG 362
+ +GF V FG T P +V LI G + +P YL++A ++G
Sbjct: 393 LSIGFNVSVSLFGGTT-PLVVTALIGATGD----MMMPAYYLMAAAVVG 436
>emb|CAB71269.1| (AL138598) putative integral membrane efflux protein. [Streptomyces
coelicolor A3(2)]
Length = 521
Score = 70.6 bits (170), Expect = 3e-11
Identities = 85/358 (23%), Positives = 154/358 (42%), Gaps = 42/358 (11%)
Query: 29 PIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSLSSALIV 88
P I KDL ++++ ++ S L + + + AG + D+ GRK+LL++ + ++L+S
Sbjct: 36 PSIQKDLDATSSQLQWMVDSYALAFGGLLLMAGGLSDRFGRKRLLSVGLGAFALTSLGAA 95
Query: 89 LTRDYWDLVTVRALYGFFAGLYYAPATALISELF-RERKGSALGFFMVGPAIGSGITPLI 147
+ L+T RAL G A L A+I ++F RE +G A+G + A+G + PL+
Sbjct: 96 FASNAEMLITFRALMGISAALMMPATLAIIKDVFPREEQGKAIGIWSGAAAVGVPLGPLV 155
Query: 148 VVPVALTLSWRYAFLV---LSIMSSIVGILLMVAIKGE---PIKVEGVKFKIPRGVFLL- 200
+ W FL+ L+ ++ I G L+ K E + + G + V ++
Sbjct: 156 SGLLLEHFWWGSMFLINVPLAAIALIGGAKLIPESKAEGHPGLDLVGALLSVAGLVAIVY 215
Query: 201 --------SLANFLGLGAFFAMLTFLVSYLVSRGVGMEKASLMFSMLSLVGILGSIIAGF 252
+ + LG+ F + +V+++ + + ML + L + G
Sbjct: 216 GLVEAPHNGWGDIITLGSLFVGVVLMVAFV------LWERKTAHPMLDVGLFLNARYGG- 268
Query: 253 LYDHLGKVSV-LLAYALNSLLTFLVIVIPSPLFLIPL--GLVLYSVGGIMTAYTSEKASR 309
G +++ ++ L S L L + S L L PL GL + ++G +M
Sbjct: 269 -----GALAIACTSFGLYSGLYLLTQYLQSVLELDPLGAGLRMLAIGTMMVGAPLSAKLV 323
Query: 310 ENLG----VVMGFVNMVGFFGATIG-------PYIVGFLIDRLGYSLALLSVPLAYLV 356
E G VV+G + G G ++G + LG +AL + A LV
Sbjct: 324 ERTGLKATVVVGLLLCAAGLGVLAGLSVDDETQALIGLAVFGLGMGIALPAAVDAILV 381
>pir||E81862 probable integral membrane transporter NMA1673 [imported] -
Neisseria meningitidis (group A strain Z2491)
>gi|7380315|emb|CAB84901.1| (AL162756) putative integral
membrane transporter [Neisseria meningitidis Z2491]
Length = 461
Score = 70.6 bits (170), Expect = 3e-11
Identities = 97/354 (27%), Positives = 154/354 (43%), Gaps = 43/354 (12%)
Query: 38 NNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLV 97
N +GL M L +L+Q+P G DK GRKK + + ++ ++ S L LV
Sbjct: 52 NKTLVGLAMGIYGLTQALLQLPLGIASDKFGRKKTIYVGLIVFAAGSFLAAAADTLPMLV 111
Query: 98 TVRALYGFFAGLYYAPATALISELFRERKGSALGFFMVGPAIGSGIT-PLIVVPV-ALTL 155
RA+ G AG A TAL+++L R+ + M+G +IG + L+V PV A +
Sbjct: 112 AARAIQG--AGAVSAAVTALLADLTRDGVRTR-AMAMIGLSIGLTFSVSLVVAPVIADAV 168
Query: 156 SWRYAFLVLSIMS-SIVGILLMVAIKGEPIKVE----------GVKFKIPR------GVF 198
R FL+ I++ + +G++ + E K+ G K R G+F
Sbjct: 169 GVRGLFLLTGILTVASIGVVAWMTPDPEVSKLHEDTQAQPSRIGEVLKNRRLLTLDFGIF 228
Query: 199 LLSLANFLGLGAFFAMLTFLVSYLVSRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLG 258
L A A F L F ++ L + K L ++ LV ++ II G + L
Sbjct: 229 ALHAAQM----ALFTALPFAMTQLGLEKIQHWKVYLPSTITGLVVMVPLIIVGETRNKLK 284
Query: 259 KVSVL----LAYALNSLLTFLVIVIPSPLFLIPLGLVLYSVG-----GIMTAYTSEKASR 309
+V +L +A A LL+ + + LI LV+Y +G + + S+ A
Sbjct: 285 QVFILGIACIAAAQLGLLSGM-----RSVGLITAYLVVYFIGFNVLEASLPSMVSKIAPS 339
Query: 310 ENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYS--LALLSV-PLAYLVSAVI 360
+ G MG N + G G G L + G+S A S+ L +LV AV+
Sbjct: 340 DLKGTAMGVYNTMQSLGLFAGGVAGGLLFQKYGFSGVFAFCSILMLLWLVIAVL 393
>gb|AAG19033.1| (AE005003) multidrug resistance protein homolog; YfmO1
[Halobacterium sp. NRC-1]
Length = 412
Score = 70.6 bits (170), Expect = 3e-11
Identities = 87/354 (24%), Positives = 144/354 (40%), Gaps = 24/354 (6%)
Query: 24 VPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSLS 83
V + P I K+LG ++ + L TS LL L + AG + +IG K + + I ++
Sbjct: 50 VDPILPSIAKELGADHFMVMFLFTSYLLVTGLANLVAGTLATRIGSKNTMLVGIGIVAVF 109
Query: 84 SALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRERKGSALGFFMVGPAIGSGI 143
+ L + +R +G L+ A A+I + G A+ + G
Sbjct: 110 AGGCALVSSVESMAVLRGFWGLGNALFTTTALAIIVGVSAGNSGRAITLYEAALGFGIAC 169
Query: 144 TPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKGEPIKV--EGVKFKI----PRGV 197
PL+ + SWR F S++ ++G + + EP EGV+ I GV
Sbjct: 170 GPLLGGFLG-AQSWRLPFAGTSVL-MLLGFVFVATTVTEPDTEGREGVRALIGTFRHTGV 227
Query: 198 FLLSLANFLGLGAFFAMLTFLVSYLVSRGVGMEKASLMFSMLSLVGILGS-IIAGFLYDH 256
++ L FF +L + + LV G + L+F L+ I+GS ++A L
Sbjct: 228 RTNAIVGMLYTYGFFTVLAY--TPLVLEGFTTMQIGLVFFAWGLLVIVGSAVLAPRLNAR 285
Query: 257 LGKVSVLLAYALNSLLTFLVI--VIPSPLFLIPLGLVLYSVGGIMTAYTSEKA---SREN 311
G V A AL + L + ++ SP+ L L + G++ A S A S +
Sbjct: 286 FGTPEVASA-ALTAFAALLCLMWLVSSPMVLAGLVVTAGLACGLLNANLSTLAMGISTHS 344
Query: 312 LGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVIIGLDL 365
G N + F G P + G++ G L +L+ A +I L L
Sbjct: 345 RPSASGAYNSLRFTGGAFAPIVAGYIGGNYG-------AALPFLLGAAVITLGL 391
>sp|Q51955|PCAK_PSEPU 4-HYDROXYBENZOATE TRANSPORTER >gi|1147822|gb|AAA85137.1| (U10895)
PcaK [Pseudomonas putida]
Length = 448
Score = 70.2 bits (169), Expect = 4e-11
Identities = 89/401 (22%), Positives = 164/401 (40%), Gaps = 71/401 (17%)
Query: 23 AVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISIL---G 79
A+ +AP + ++ GI+ A +G +M++ L+ + +G + D+ GRK +L ++L G
Sbjct: 47 AMGFIAPALSQEWGIDRASLGPVMSAALIGMVFGALGSGPLADRFGRKGVLVGAVLVFGG 106
Query: 80 YSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRERKGSALGF-----FM 134
+SL+SA + L+ +R L G G AT L+SE ER S L F
Sbjct: 107 FSLASA---YATNVDQLLVLRFLTGLGLGAGMPNATTLLSEYTPERLKSLLVTSMFCGFN 163
Query: 135 VGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIK-------------- 180
+G A G G ++P W ++ ++ ++ ++LMV +
Sbjct: 164 LGMA-GGGFISAKMIP---AYGWHSLLVIGGVLPLLLALVLMVWLPESARFLVVRNRGTD 219
Query: 181 ---------GEPIKVEGVKFKIPR--------------------GVFLLSLANFLGLGAF 211
+ E F +P G LL L F+GL
Sbjct: 220 KIRKTLSPIAPQVVAEAGSFSVPEQKAVAARSVFAVIFSGTYGLGTMLLWLTYFMGLVIV 279
Query: 212 FAMLTFLVSYLVSRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVL-LAYALNS 270
+ + ++L + + G ME+A+ + ++ G+L ++ G+ D V+ + Y L
Sbjct: 280 YLLTSWLPTLMRDSGASMEQAAFIGALFQFGGVLSAVGVGWAMDRYNPHKVIGIFYLLAG 339
Query: 271 LLTFLV------IVIPSPLFLIPLGLVLYSVGGIMTAYTSEKASRENLGVVMGFVNMVGF 324
+ + V I + + L LI G+ + M + + + + ++ +G
Sbjct: 340 VFAYAVGQSLGNITVLATLVLI-AGMCVNGAQSAMPSLAARFYPTQGRATGVSWMLGIGR 398
Query: 325 FGATIGPYIVGFLIDRLGYS----LALLSVPLAYLVSAVII 361
FGA +G + L+ LG++ L L VP A VI+
Sbjct: 399 FGAILGAWSGATLLG-LGWNFEQVLTALLVPAALATVGVIV 438
>gb|AAK42225.1| Metabolite transport protein [Sulfolobus solfataricus]
Length = 427
Score = 70.2 bits (169), Expect = 4e-11
Identities = 87/349 (24%), Positives = 150/349 (42%), Gaps = 43/349 (12%)
Query: 61 GYIGDKIGRKKLLTISILGYSLSSALIVLTRDY--------WDLVTVRALYGFFAGLYYA 112
G++GDKIGRK L I++ LSS L Y L +R L GF G +
Sbjct: 68 GHLGDKIGRKYTLIITMTLMGLSSLFTGLLPGYAILGVLAPTLLTILRLLQGFSLGGEFG 127
Query: 113 PATALISELFRERK-----GSALGFFMVGPAIGSG---ITPLIVVPVAL-TLSWRYAFLV 163
L +E K G A +GP + +G + I++P A ++ WR F++
Sbjct: 128 GGITLSAEFAEPGKRAFYTGIAQMAQGIGPLMATGLIFVFSSIMLPSAFASIGWRILFII 187
Query: 164 LSIMSSIVGILLMVAIKGEPI------KVEGVKFKIPRGVFLLSLANFLGLGAF------ 211
+ + +++G+++ + I P+ K E F + + LGLG
Sbjct: 188 GAFI-AVIGVMIRLKISESPVFKKVKEKNEISHFPLVDAFRIYWKRILLGLGFIIGGTTM 246
Query: 212 -FAMLTFLVSYLVS-RGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALN 269
+A F SYL + GV SL ++ +V + ++ L D +G+ +++A A+
Sbjct: 247 TYATSVFASSYLENVIGVPARLVSLALTIGYIVEAISILLFAMLADKVGRKPLMVATAVG 306
Query: 270 SLL---TFLVIVIPSPLFLIPLGLVLYSVGGIMTAYTSEKASRENLGVVMGFVNM----- 321
L+ + +++ LI L ++YSV G M+ A E + + +
Sbjct: 307 LLILVYPYFLLISTGQFSLILLAQIMYSVIGSMSTGAYATALTELFPTKVRYTALSFDYH 366
Query: 322 --VGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVIIGLDLRKT 368
V FG T P+I +LI GY LA + +A ++ +I L ++T
Sbjct: 367 VGVAVFGGTT-PFIASYLIYATGYKLAPVYWGIAGMILTLIAYLLYKET 414
>pir||S74875 quinolone resistance protein norA - Synechocystis sp. (strain PCC
6803) >gi|1652918|dbj|BAA17836.1| (D90909) quinolene
resistance protein NorA [Synechocystis sp.]
Length = 418
Score = 70.2 bits (169), Expect = 4e-11
Identities = 91/393 (23%), Positives = 165/393 (41%), Gaps = 31/393 (7%)
Query: 2 EKLIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAG 61
+K L+ S+ +F S +P+L P+ +D+G ++G +M S L ++ G
Sbjct: 15 QKTFALLFASV-LMFWLSLTALLPTL-PMYAQDVGATKQQVGWIMGSFALGLLGSRIWIG 72
Query: 62 YIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISEL 121
+ D+ GRK + I L +L+ +LT L+ +RA +G Y +L+ +L
Sbjct: 73 QLVDRRGRKIAIVIGALVVALAPLGYLLTATVGALMAIRAFHGICLAAYTTGYNSLVVDL 132
Query: 122 F-RERKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIK 180
+++G +G+ + IG G P + ++ ++ + + F+ S++ I +L + +
Sbjct: 133 SPPQQRGEIIGYMSLAVPIGMGFGPAVGAYISQSIGYEFLFIASSLLGFISLVLALQVRE 192
Query: 181 GEP---IKVEGVKFKIPR----GVFLLSLAN------FLGLGAFFAMLTFLVSYLVSRGV 227
P E V PR G L S + L +G F L + V
Sbjct: 193 NRPPDQSSAEDVFGDRPRPRSIGKLLTSRSMAVPTLVLLLIGLLFGNLATFLPLFVREID 252
Query: 228 GMEKASLMFSMLSLVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIP 287
A + +S+ ++ + + G L D G+ ++ + LL+ + + + +
Sbjct: 253 LATYAGVFYSVAAIASFVPRLFLGSLADTYGRGLFIVGSLICYLLSMVCLAQADNSWELL 312
Query: 288 LGLVLYSVG-GIM----TAYTSEKASRENLGVVMGFVNMVGFFGA-TIGPYIVGFLIDRL 341
L G GI+ A S+++S E G V V M GF G I I+G L +
Sbjct: 313 TAAALEGAGSGILLPTTIALISDRSSLEERGRVFS-VCMSGFDGGIAIAAPIMGVLNEIF 371
Query: 342 GY--------SLALLSVPLAYLVSAVIIGLDLR 366
GY LAL ++ + + S IG LR
Sbjct: 372 GYRHVFWLSGGLALAAIMVFGIFSNPTIGRSLR 404
>gb|AAB70881.1| (U86689) exuT [Pectobacterium chrysanthemi]
Length = 345
Score = 70.2 bits (169), Expect = 4e-11
Identities = 43/163 (26%), Positives = 78/163 (47%), Gaps = 1/163 (0%)
Query: 9 LISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIG 68
L+++G + Y R A+ + AP + + L I+ + ++ + Y+++Q AGY+ D +G
Sbjct: 14 LVTIGTVLGYLTRNAIAAAAPTLQEQLHISTQQYSYIIAAYSACYTIMQPVAGYVLDVLG 73
Query: 69 RKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRERKGS 128
K + + ++L A L + L R G SE F ++ S
Sbjct: 74 TKVGYAMFAILWALFCAGTALANSWGGLAVARGAVGMAEAAMIPAGLKASSEWFPAKERS 133
Query: 129 -ALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSI 170
A+G+F VG +IG + P +VV + SW+ AFL+ +S +
Sbjct: 134 VAVGYFNVGSSIGGMLAPPLVVWAIMAHSWQMAFLITGALSLV 176
>gb|AAK41393.1| Transport protein, permease [Sulfolobus solfataricus]
Length = 371
Score = 69.9 bits (168), Expect = 5e-11
Identities = 89/356 (25%), Positives = 162/356 (45%), Gaps = 24/356 (6%)
Query: 16 FNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTI 75
FN ++ + +L P++ + ++ EI L T + S+ Q G+ DK G K++ I
Sbjct: 16 FNSLYQYSWNALEPLLREGFNVSVVEIALGFTLFSVFSSVFQPIGGHFADKQGPKRIGVI 75
Query: 76 SILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELFRERKGSALGFFMV 135
S + ++ L+ + + ++ G+ Y A L + FRER G A G +
Sbjct: 76 SAILSAIGFLGTYLSPNIYVFFVSWSIGSIGEGILYGIAANLAMKWFRERMGFATGIVSM 135
Query: 136 GPAIGSGI-TPLIVVPVALTLSWRYAFLVLSI-MSSIVGILLMVAIKGEPIKVEGVKFKI 193
G IGS I P I +++ Y + L+I + IV + +++ I P K+ G +
Sbjct: 136 GFGIGSAIANPFI------SMAGNYRIVTLAIGLVEIVLLPILLYISDYPPKLSG---QT 186
Query: 194 PRGVFL--LSLANFLGLGAFFAMLTFLVSYLVSRGVGMEKASLMFSMLSLVGILGS---I 248
PR L +L LT L S L G G+ + L+ +++S++ +L
Sbjct: 187 PRQAVLSVKFWLIYLSFATSIVPLTVLSSELPILGKGLPQQELV-TLISILPLLSGGLRP 245
Query: 249 IAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSVGGIMTAYTSEKAS 308
I G++ D LG + + L +LT I + + LV ++ G ++T Y + S
Sbjct: 246 IFGYIADRLGILRT--TFLLTIVLTLGSISLLLGEIALSTILVGFAGGSLITLYFN--VS 301
Query: 309 RENLGVVMGFVNM-VGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVIIGL 363
E G VN + + G +G ++G +I L Y+++L + + Y +S +IG+
Sbjct: 302 TEIFGFKFSTVNSGILYTGKALGG-VLGSIIFALLYTISLRTSEI-YTLSCSLIGV 355
>sp|P13924|TCR_STRAG TETRACYCLINE RESISTANCE PROTEIN >gi|581578|emb|CAA33712.1| (X15669)
tetL protein (AA 1-458) [Streptococcus agalactiae]
Length = 458
Score = 69.9 bits (168), Expect = 5e-11
Identities = 85/369 (23%), Positives = 161/369 (43%), Gaps = 41/369 (11%)
Query: 6 ILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGD 65
ILI + + F+ + M + P I D A + T+ +L +S+ G + D
Sbjct: 15 ILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSD 74
Query: 66 KIGRKKLLTISILGYSLSSALIVLTRDYWDL-VTVRALYGFFAGLYYAPATALISELF-R 123
++G K+LL I+ S + + ++ L + R + G A + A +++ +
Sbjct: 75 QLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPK 134
Query: 124 ERKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLSIMSSIVGILLMVAIKGEP 183
E +G A G A+G G+ P IV +A + W Y L+L M +I+ + ++ + +
Sbjct: 135 ENRGKAFGLIGSIVAMGEGVGPAIVGMIAHYIHWSY--LLLIPMITIITVPFLMKLLKKE 192
Query: 184 IKVEGVKFKIPRGVFLLSLANFLGLGAFFAMLTFLVSYLVSRGVGMEKASLMFSMLSLVG 243
++++G F I +G+ L+S +G F ML F SY +S L+ S+LS +
Sbjct: 193 VRIKG-HFDI-KGIILMS------VGIVFFML-FTTSYSIS--------FLIVSVLSFL- 234
Query: 244 ILGSIIAGFLYDHLGKVS-VLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSVGGI--MT 300
H+ KV+ + L + F++ V+ G++ +V G M
Sbjct: 235 --------IFVKHIRKVTDPFVDPGLGKNILFMIGVLCG-------GIIFGTVAGFVSMV 279
Query: 301 AYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFLIDRLGYSLALLSVPLAYLVSAVI 360
Y + + + + + G I YI G L+DR G L +L++ + +L + +
Sbjct: 280 PYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRG-PLYVLNIGVTFLSVSFL 338
Query: 361 IGLDLRKTS 369
L +T+
Sbjct: 339 TAFFLLETT 347
>pir||T37042 probable nitrate/nitrite transport protein - Streptomyces
coelicolor >gi|5777686|emb|CAB53437.1| (AL109989)
putative nitrate/nitrite transporter protein
[Streptomyces coelicolor A3(2)]
Length = 412
Score = 69.9 bits (168), Expect = 5e-11
Identities = 92/383 (24%), Positives = 163/383 (42%), Gaps = 39/383 (10%)
Query: 5 IILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIG 64
++L L +LG+ N+ + L P L +++ + LL+ ++ SL ++P G +
Sbjct: 22 LMLALATLGFALNFWAWALLSPLGPRFKDSLDLSSFQQSLLVAVPVVVGSLGRIPVGALT 81
Query: 65 DKIGRKKLLTISILGYSLSSALIVLTRDYWDL-----VTVRALYGFFAGL---YYAPATA 116
D+ G + + + L SA ++ Y L +T + GF G+ +A
Sbjct: 82 DRFGGRVM-------FPLVSAATIVPVLYLGLAGHSSLTALLVGGFLLGIGGTAFAVGVP 134
Query: 117 LISELF-RERKGSALGFFMVGPAIGSGITPLIVVPVALTLSWRYAFLVLS---IMSSIVG 172
S F ER+G A+G F G G+ I+ L V + FLV + + ++V
Sbjct: 135 FTSAWFPPERRGLAIGIFGAGMG-GTAISALTTVKLVDAYGMANPFLVTAAVLAVYAVVA 193
Query: 173 ILLMVAIKGEPIKVEGVKFKIPRGVFL-----LSLANFLGLGAFFAMLTFLVSYLVSRGV 227
LL+ G + E + ++ L S + G + A +L +YL G
Sbjct: 194 ALLLRDAPGRTVPAESLGHRMAATCKLGITWQASALYAVAFGGYVAFSVYLPTYL-KTGY 252
Query: 228 GMEKASLMFSMLS--LVGILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPSPLFL 285
G+ +A M L+ + + G+L D LG V V LA +L +L + P+P L
Sbjct: 253 GLTQADAANRMAGFVLLAVAMRPMGGWLSDRLGPVKV-LAGSLAVVLAGALAQSPTPA-L 310
Query: 286 IPLGLVLY--------SVGGIMTAYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVGFL 337
+P+G + + + G + A + + +G V G V G G + P ++G L
Sbjct: 311 MPVGTIAFLAMAAALGAGSGAVFALVAFLSPANKVGSVTGMVGAAGGLGGFLPPLVMGTL 370
Query: 338 IDRLGYSLALLSVPLAYLVSAVI 360
G S A+ + LA + +A +
Sbjct: 371 YGSFG-SYAIGLILLAAVAAAAL 392
>pir||B81080 drug resistance translocase family protein NMB1461 [imported] -
Neisseria meningitidis (group B strain MD58)
>gi|7226703|gb|AAF41820.1| (AE002496) drug resistance
translocase family protein [Neisseria meningitidis MC58]
Length = 461
Score = 69.5 bits (167), Expect = 6e-11
Identities = 96/350 (27%), Positives = 152/350 (43%), Gaps = 35/350 (10%)
Query: 38 NNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLV 97
N +GL M L +L+Q+P G DK GRKK + ++ ++ S L LV
Sbjct: 52 NKTLVGLAMGIYGLTQALLQLPLGIASDKFGRKKTIYAGLVVFAAGSFLAAAADTLPMLV 111
Query: 98 TVRALYGFFAGLYYAPATALISELFRERKGSALGFFMVGPAIGSGIT-PLIVVPV-ALTL 155
RA+ G AG A TAL+++L R+ + M+G +IG + L+V PV A +
Sbjct: 112 AARAIQG--AGAVSAAVTALLADLTRDGVRTR-AMAMIGLSIGLTFSVSLVVAPVIADAV 168
Query: 156 SWRYAFLVLSIMSSI-VGILLMVAIKGEPIKVE----------GVKFKIPR------GVF 198
R F++ I++ I +G++ + E K+ G K R G+F
Sbjct: 169 GVRGLFMLTGILTVISIGVVAWMTPDPEVSKLHEDTQAQPSRIGEVLKNRRLLTLDFGIF 228
Query: 199 LLSLANFLGLGAFFAMLTFLVSYLVSRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLG 258
L A A F L F ++ L + K L ++ LV ++ II G + L
Sbjct: 229 ALHAAQM----ALFTALPFAMTQLGLEKIQHWKVYLPSTITGLVVMVPLIIVGETRNKLK 284
Query: 259 KVSVLLAYALNSLLTFLVIVIPSPLFLIPLGLVLYSVG-----GIMTAYTSEKASRENLG 313
+V VL + + L+ + S + LI LV+Y +G + + S+ A + G
Sbjct: 285 QVFVLGIVCIAAAQLGLLSGMRS-VGLITAYLVVYFIGFNVLEASLPSMVSKIAPSDLKG 343
Query: 314 VVMGFVNMVGFFGATIGPYIVGFLIDRLGYS--LALLSV-PLAYLVSAVI 360
MG N + G G G L + G+S A S+ L +LV AV+
Sbjct: 344 TAMGVYNTMQSLGLFAGGAAGGLLFQKYGFSGVFAFCSILMLLWLVIAVL 393
>pir||G83322 hypothetical protein PA2589 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9948652|gb|AAG05977.1|AE004687_6
(AE004687) hypothetical protein [Pseudomonas aeruginosa]
Length = 404
Score = 69.5 bits (167), Expect = 6e-11
Identities = 86/348 (24%), Positives = 143/348 (40%), Gaps = 31/348 (8%)
Query: 38 NNAEIGLLMTSLLLPYSLIQVPAGYIGDKIGRKKLLTISILGYSLSSALIVLTRDYWDLV 97
+ AE+ LL+T L ++ G++ D+ G ++ + SL + W L
Sbjct: 47 DRAEVSLLVTLFGLAVAITSPLKGWLIDRWGARRTMLGLTAALSLPLLGLAAVNAVWQLY 106
Query: 98 TVRALYGFFAGLYYAPATALISELFRERKGSALGFFMVGPAIGSGITPLIVVPVALTLSW 157
+ L G A P ++ FR+R G A G +G +G + L+ W
Sbjct: 107 ALFLLIGLLAP-GNLPYGRILGLWFRQRLGVAYGLLGLGFGVGGPLGLLVGHQSLEAWGW 165
Query: 158 RYAFLVLSIMSSIVGILLMVAIKGEPIKVEGVKFKIP----------------RGVFLLS 201
R AFLV ++ + + L+ + EP GV F L
Sbjct: 166 RGAFLVYGVLELGLALPLLAWLFREPAPDAGVAAGTAVAETALSGSTAPQAWRSASFWLV 225
Query: 202 LAN-FLGLGAFFAMLTFLVSYLVSRGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLGKV 260
L N L + ++T V LV RG+ +A S L + +L + G+L D +
Sbjct: 226 LGNQVLAVFVMSGIMTHGVPMLVERGLSRGEAGTALSALWVGMMLSQPLMGWLLDRVATP 285
Query: 261 SVLLAYALNSLL---TFLVIVIPSPLFLIPLGLVLYSVGGIMTAYTSEKA-----SRENL 312
V L +AL ++L FLV PS L+ L + L +GG + T++ +
Sbjct: 286 RVALPFALAAVLGMAWFLVGDTPSGLW---LAVFLVGLGGGGESGTTKYLLMRYFGLRSF 342
Query: 313 GVVMGFVNMVGF-FGATIGPYIVGFLIDRL-GYSLALLSVPLAYLVSA 358
GV+ G + F ++G Y++G+L DR GY A + A+ ++A
Sbjct: 343 GVIYGSIQPFTFALSISLGAYLLGWLYDRAEGYGTAEWVLLAAFSLAA 390
>pir||F82177 probable multidrug resistance protein VC1618 [imported] - Vibrio
cholerae (group O1 strain N16961)
>gi|9656131|gb|AAF94772.1| (AE004239) multidrug
resistance protein, putative [Vibrio cholerae]
Length = 405
Score = 69.1 bits (166), Expect = 8e-11
Identities = 85/373 (22%), Positives = 159/373 (41%), Gaps = 40/373 (10%)
Query: 4 LIILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYI 63
L + ++ G + + + P + ++ +I L + L SL VP
Sbjct: 10 LKVTFALAFGSFLVFCNLYLFQPMLPYLANHFAVSETQINWLFAASTLALSLCLVPWAVT 69
Query: 64 GDKIGRKKLLTISILGYSLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATA-LISELF 122
+ +GR+ ++ + + ++ +W LV RAL G + + A A ++ EL
Sbjct: 70 SEAVGRRLVMLTGLFAMPVIGLAMLYAEQFWFLVLTRALMGVALAAFASVAVAYMVEELS 129
Query: 123 RERKGSALGFFMVGPAIGSGITPLIVVPVAL-TLSWRYAFLVLSIMSSIVGILLMVAIKG 181
+ G A+G ++ ++G GIT I + L W++A + ++I +++G LL+ +
Sbjct: 130 PQAFGKAIGGYIAANSLG-GITGRIAGGLLTDALGWQHAVVAMAIF-TLLGALLVAYLL- 186
Query: 182 EPIKVEGVKFKIPRGVFL--------------LSLANFLGLGAFFAMLTFLVSYLVSRGV 227
PI+ FK RG+F L LA +G G FA+ L S + R V
Sbjct: 187 -PIQQH---FKPQRGLFFHHNRALVKHLQNRTLWLAMLIG-GVNFALFVNLYSVMGFRLV 241
Query: 228 GMEKASLMFSMLSLV------GILGSIIAGFLYDHLGKVSVLLAYALNSLLTFLVIVIPS 281
E SL + SL+ G L S + + ++ AL S+ L+ +I +
Sbjct: 242 A-EPYSLPIGIASLIFVCYLAGTLSSKLTANWNRRFSAIPGMMLGALISMAGMLIALIEA 300
Query: 282 -PLFLIPLGLVLYSVGGIMT-----AYTSEKASRENLGVVMGFVNMVGFFGATIGPYIVG 335
P L+ GL+L S G T A+ S+KA++ ++ + + G ++G + +
Sbjct: 301 IPAMLV--GLILISFGAFFTHTLAYAWVSQKATQAKATATALYL-VHYYIGGSLGGFYLL 357
Query: 336 FLIDRLGYSLALL 348
+ G+ + L
Sbjct: 358 YCWQHGGWEMVTL 370
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.329 0.147 0.421
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 122815260
Number of Sequences: 2977
Number of extensions: 5051200
Number of successful extensions: 21687
Number of sequences better than 1.0e-10: 105
Number of HSP's better than 0.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 102
Number of HSP's that attempted gapping in prelim test: 21444
Number of HSP's gapped (non-prelim): 153
length of query: 372
length of database: 189,106,746
effective HSP length: 54
effective length of query: 318
effective length of database: 156,788,448
effective search space: 49858726464
effective search space used: 49858726464
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (21.7 bits)
S2: 166 (69.1 bits)