BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0762 (PAB0762) DE:PROLYL ENDOPEPTIDASE
(614 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||E75094 prolyl endopeptidase PAB0762 - Pyrococcus abyssi (st... 1263 0.0
pir||JC4084 prolyl endopeptidase (EC 3.4.-.-) - Pyrococcus furio... 1121 0.0
pir||B71071 probable prolyl endopeptidase - Pyrococcus horikoshi... 1106 0.0
pir||B75267 prolyl endopeptidase - Deinococcus radiodurans (stra... 286 4e-76
gb|AAD31004.1|AF127082_3 (AF127082) prolyl endopeptidase precurs... 263 3e-69
gb|AAD34991.1| (AF143951) prolyl endopeptidase [Aeromonas puncta... 254 2e-66
gb|AAF02211.1| (AF065429) prolyl endopeptidase [Aeromonas puncta... 253 4e-66
pdb|1QFM|A Chain A, Prolyl Oligopeptidase From Porcine Muscle 249 5e-65
sp|P23687|PPCE_PIG PROLYL ENDOPEPTIDASE (POST-PROLINE CLEAVING E... 249 9e-65
gi|4506043 prolyl endopeptidase [Homo sapiens] >gi|1346769|sp|P4... 247 3e-64
pdb|1E5T|A Chain A, Prolyl Oligopeptidase From Porcine Brain, Mu... 247 4e-64
pir||JN0585 prolyl oligopeptidase (EC 3.4.21.26) - Aeromonas hyd... 246 5e-64
sp|Q06903|PPCE_AERHY PROLYL ENDOPEPTIDASE (POST-PROLINE CLEAVING... 246 5e-64
dbj|BAA86936.1| (AB020018) prolyl endopeptidase [Homo sapiens] 246 6e-64
pir||JC2257 prolyl oligopeptidase (EC 3.4.21.26) - human >gi|904... 243 3e-63
pir||JC5877 prolyl oligopeptidase (EC 3.4.21.26) - bovine >gi|51... 241 2e-62
gi|6755152 prolyl endopeptidase [Mus musculus] >gi|7435601|pir||... 241 2e-62
gb|AAF52942.1| (AE003628) CG5355 gene product [Drosophila melano... 241 2e-62
gb|AAG10464.1|AF279106_26 (AF279106) predicted prolyl endopeptid... 239 8e-62
sp|P27028|PPCE_FLAME PROLYL ENDOPEPTIDASE PRECURSOR (POST-PROLIN... 239 8e-62
dbj|BAA25544.1| (AB012759) rPOP [Rattus norvegicus] 237 3e-61
sp|P27195|PPCF_FLAME PROLYL ENDOPEPTIDASE PRECURSOR (POST-PROLIN... 236 5e-61
pir||A38086 prolyl oligopeptidase (EC 3.4.21.26) precursor - Fla... 236 5e-61
dbj|BAA34052.1| (AB010298) prolyl oligopeptidase [Sphingomonas c... 233 6e-60
emb|CAB40787.1| (AJ238018) prolyl oligopeptidase [Dictyostelium ... 221 2e-56
gb|AAF88151.1|AC026234_2 (AC026234) Contains similarity to a rPO... 220 3e-56
gb|AAF57241.1| (AE003782) CG2528 gene product [Drosophila melano... 207 3e-52
gi|11419026 prolyl endopeptidase [Homo sapiens] 194 3e-48
pir||C81033 prolyl oligopeptidase family protein NMB1877 [import... 185 2e-45
pir||B70528 probable peptidase - Mycobacterium tuberculosis (str... 183 6e-45
pir||H81976 probable prolyl oligopeptidase (EC 3.4.21.26) NMA057... 181 2e-44
sp|Q59536|PTRB_MORLA PROTEASE II (OLIGOPEPTIDASE B) >gi|1084058|... 179 9e-44
sp|P55577|Y4NA_RHISN PROBABLE PEPTIDASE Y4NA >gi|2182536|gb|AAB9... 175 2e-42
emb|CAB39326.1| (AJ000250) hypothetical protein [Neisseria menin... 167 3e-40
sp|P81171|Y174_RICPR PROBABLE PEPTIDASE RP174 >gi|7467917|pir||B... 167 4e-40
gb|AAC80459.1| (AF078916) oligopeptidase B [Trypanosoma brucei b... 164 2e-39
gb|AAD24761.1|AF109875_1 (AF109875) oligopeptidase B [Leishmania... 160 5e-38
gb|AAC80228.1| (U69897) oligopeptidase B [Trypanosoma cruzi] 158 2e-37
pir||JQ1151 proteinase II (EC 3.4.21.-) - Escherichia coli >gi|2... 157 3e-37
sp|P24555|PTRB_ECOLI PROTEASE II (OLIGOPEPTIDASE B) >gi|7428207|... 157 3e-37
pir||D83481 probable oligopeptidase PA1304 [imported] - Pseudomo... 148 1e-34
gb|AAF43045.1|AF237705_1 (AF237705) oligopeptidase B [Salmonella... 148 2e-34
pir||B82677 peptidase XF1479 [imported] - Xylella fastidiosa (st... 145 1e-33
dbj|BAA20518.1| (AB004795) dipeptidyl aminopeptidase [Pseudomona... 142 1e-32
gb|AAF17627.1|AC009978_3 (AC009978) T23E18.7 [Arabidopsis thaliana] 141 2e-32
emb|CAB08412.1| (Z95151) PtrB [Mycobacterium leprae] 136 1e-30
pir||D71683 proteinase II (ptrB) RP281 - Rickettsia prowazekii >... 135 1e-30
gb|AAD50051.1|AC007980_16 (AC007980) Similar to oligopeptidases ... 133 6e-30
pir||A70709 probable ptrBa protein - Mycobacterium tuberculosis ... 130 4e-29
pir||E82506 proteinase II VCA0063 [imported] - Vibrio cholerae (... 130 4e-29
sp|P55656|Y4SO_RHISN PROBABLE PEPTIDASE Y4SO >gi|2182630|gb|AAB9... 104 3e-21
gb|AAF07357.1|AC011665_16 (AC011665) putative protease [Arabidop... 103 5e-21
dbj|BAB08935.1| (AB026640) protease-like [Arabidopsis thaliana] 87 4e-16
dbj|BAA23709.1| (AB007896) KIAA0436 [Homo sapiens] 86 1e-15
sp|P55627|Y4QF_RHISN PROBABLE PEPTIDASE Y4QF >gi|2182591|gb|AAB9... 81 3e-14
gb|AAF17628.1|AC009978_4 (AC009978) T23E18.8 [Arabidopsis thaliana] 81 4e-14
>pir||E75094 prolyl endopeptidase PAB0762 - Pyrococcus abyssi (strain Orsay)
>gi|5458570|emb|CAB50058.1| (AJ248286) PROLYL
ENDOPEPTIDASE [Pyrococcus abyssi]
Length = 614
Score = 1263 bits (3233), Expect = 0.0
Identities = 614/614 (100%), Positives = 614/614 (100%)
Query: 1 MEDPYIWMENLQDERVLKIVEEENRRFRELVGELSDKLFPEVWEYFSQPSIGMARITKRG 60
MEDPYIWMENLQDERVLKIVEEENRRFRELVGELSDKLFPEVWEYFSQPSIGMARITKRG
Sbjct: 1 MEDPYIWMENLQDERVLKIVEEENRRFRELVGELSDKLFPEVWEYFSQPSIGMARITKRG 60
Query: 61 IIVSYSEKDRVTVRWLGGEVIVDSKELEKELNDEVLLQGFTTDEDGKRLAYSFSIGGSDE 120
IIVSYSEKDRVTVRWLGGEVIVDSKELEKELNDEVLLQGFTTDEDGKRLAYSFSIGGSDE
Sbjct: 61 IIVSYSEKDRVTVRWLGGEVIVDSKELEKELNDEVLLQGFTTDEDGKRLAYSFSIGGSDE 120
Query: 121 GITRIIDLETGELLEEIKPSVWNIVFLDKGYYFARFYRKEKTPDGVNPPAERIFWKDEEG 180
GITRIIDLETGELLEEIKPSVWNIVFLDKGYYFARFYRKEKTPDGVNPPAERIFWKDEEG
Sbjct: 121 GITRIIDLETGELLEEIKPSVWNIVFLDKGYYFARFYRKEKTPDGVNPPAERIFWKDEEG 180
Query: 181 ERMVFGEGLTSGYFMSLRKSTDGKFAMLTLTYGWNKAEIYLGPIDKPEEWKKVYSADVPA 240
ERMVFGEGLTSGYFMSLRKSTDGKFAMLTLTYGWNKAEIYLGPIDKPEEWKKVYSADVPA
Sbjct: 181 ERMVFGEGLTSGYFMSLRKSTDGKFAMLTLTYGWNKAEIYLGPIDKPEEWKKVYSADVPA 240
Query: 241 EPIDVIDGKLYILTKEGKGLGKVIAVKDSEVEEIIPEGEFPLEWAVIVKDKILAGRLVHA 300
EPIDVIDGKLYILTKEGKGLGKVIAVKDSEVEEIIPEGEFPLEWAVIVKDKILAGRLVHA
Sbjct: 241 EPIDVIDGKLYILTKEGKGLGKVIAVKDSEVEEIIPEGEFPLEWAVIVKDKILAGRLVHA 300
Query: 301 SHKLEVYNLKGEKISEVEFDFPGSLYPLDKDDERALLRYTSFTVPYRIYEFKDELKIVEE 360
SHKLEVYNLKGEKISEVEFDFPGSLYPLDKDDERALLRYTSFTVPYRIYEFKDELKIVEE
Sbjct: 301 SHKLEVYNLKGEKISEVEFDFPGSLYPLDKDDERALLRYTSFTVPYRIYEFKDELKIVEE 360
Query: 361 RKVEGNFKVEEDFAISKDGTRVHYFIVKGEKDEKKAWVFGYGGFNISLTPRFFPQVIPFL 420
RKVEGNFKVEEDFAISKDGTRVHYFIVKGEKDEKKAWVFGYGGFNISLTPRFFPQVIPFL
Sbjct: 361 RKVEGNFKVEEDFAISKDGTRVHYFIVKGEKDEKKAWVFGYGGFNISLTPRFFPQVIPFL 420
Query: 421 KRGGIFVMANLRGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGYKVAAWGRSNGG 480
KRGGIFVMANLRGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGYKVAAWGRSNGG
Sbjct: 421 KRGGIFVMANLRGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGYKVAAWGRSNGG 480
Query: 481 LLVSATLVQRPDVMDVALIGYPVIDMLRFHKLYIGSVWIPEYGNPDDPKDREFLLKYSPY 540
LLVSATLVQRPDVMDVALIGYPVIDMLRFHKLYIGSVWIPEYGNPDDPKDREFLLKYSPY
Sbjct: 481 LLVSATLVQRPDVMDVALIGYPVIDMLRFHKLYIGSVWIPEYGNPDDPKDREFLLKYSPY 540
Query: 541 HNVRPQEYPPTLIYTGLHDDRVHPAHALKFFMKLKEVNAPVYLRVETKSGHMGASPETRA 600
HNVRPQEYPPTLIYTGLHDDRVHPAHALKFFMKLKEVNAPVYLRVETKSGHMGASPETRA
Sbjct: 541 HNVRPQEYPPTLIYTGLHDDRVHPAHALKFFMKLKEVNAPVYLRVETKSGHMGASPETRA 600
Query: 601 RELTDLLAFVLLHL 614
RELTDLLAFVLLHL
Sbjct: 601 RELTDLLAFVLLHL 614
>pir||JC4084 prolyl endopeptidase (EC 3.4.-.-) - Pyrococcus furiosus
>gi|475592|gb|AAA73423.1| (U08343) prolyl endopeptidase
[Pyrococcus furiosus]
Length = 616
Score = 1121 bits (2868), Expect = 0.0
Identities = 520/612 (84%), Positives = 577/612 (93%), Gaps = 1/612 (0%)
Query: 1 MEDPYIWMENLQDERVLKIVEEENRRFRELVGELSDKLFPEVWEYFSQPSIGMARITKRG 60
MEDPYIWMENL+DERVLKI+EEEN+RFRE +GELSDKLFPEVWE FSQP+IGMARITK+G
Sbjct: 1 MEDPYIWMENLEDERVLKIIEEENKRFREFIGELSDKLFPEVWEQFSQPTIGMARITKKG 60
Query: 61 IIVSYSEKDRVTVRWLGGEVIVDSKELEKELNDEVLLQGFTTDEDGKRLAYSFSIGGSDE 120
II SYSEKDRV ++W G+VIVDSKELE+E+ DEVLLQGFTTDE+G++LAYSFSIGG+DE
Sbjct: 61 IIASYSEKDRVVIKWFNGDVIVDSKELEREVGDEVLLQGFTTDEEGEKLAYSFSIGGADE 120
Query: 121 GITRIIDLETGELLEEIKPSVWNIVFLDKGYYFARFYRKEKTPDGVNPPAERIFWKDEEG 180
GITRIIDL+TGE++EEIKPS+WNI FL GYYF RFYRKEKTPDGVNPPA R+FWKD EG
Sbjct: 121 GITRIIDLKTGEVIEEIKPSIWNITFLKDGYYFTRFYRKEKTPDGVNPPAARMFWKDREG 180
Query: 181 ERMVFGEGLTSGYFMSLRKSTDGKFAMLTLTYGWNKAEIYLGPIDKPEEWKKVYSADVPA 240
ERMVFGEGLTSGYFMS+RKS+DGKFA++TLTYGWN+ E+Y+GPID P+EWKKVYSA VP
Sbjct: 181 ERMVFGEGLTSGYFMSIRKSSDGKFAIVTLTYGWNQGEVYIGPIDNPQEWKKVYSASVPV 240
Query: 241 EPIDVIDGKLYILTKEGKGLGKVIAVKDSEVEEIIPEGEFPLEWAVIVKDKILAGRLVHA 300
E IDV++GKLYILTKEGKGLGK+IA+K+ +++E+IPEGEFPLEWAVIV+DKILAGRLVHA
Sbjct: 241 EAIDVVNGKLYILTKEGKGLGKIIAIKNGKIDEVIPEGEFPLEWAVIVRDKILAGRLVHA 300
Query: 301 SHKLEVYNLKGEKISEVEFDFPGSLYPLDKDDERALLRYTSFTVPYRIYEFKDELKIVEE 360
S+KLEVY L GEKI E+ FD PGSLYPLDKD+ER LLRYTSFT+PYR+YEFKD+L+++EE
Sbjct: 301 SYKLEVYTLNGEKIKEITFDVPGSLYPLDKDEERVLLRYTSFTIPYRLYEFKDDLRLIEE 360
Query: 361 RKVEGNFKVEEDFAISKDGTRVHYFIVKGEKDEKKAWVFGYGGFNISLTPRFFPQVIPFL 420
RKVEG F+VEEDFA SKDGT+VHYFIVKGE+DEK+AWVFGYGGFNI+LTP FFPQVIPFL
Sbjct: 361 RKVEGEFRVEEDFATSKDGTKVHYFIVKGERDEKRAWVFGYGGFNIALTPMFFPQVIPFL 420
Query: 421 KRGGIFVMANLRGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGYKVAAWGRSNGG 480
KRGG F+MANLRGGSEYGEEWHRAGMRENKQNVFDDFIAVLEK KKEGYKVAAWGRSNGG
Sbjct: 421 KRGGTFIMANLRGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKRKKEGYKVAAWGRSNGG 480
Query: 481 LLVSATLVQRPDVMDVALIGYPVIDMLRFHKLYIGSVWIPEYGNPDDPKDREFLLKYSPY 540
LLVSATL QRPDVMD ALIGYPVIDMLRFHKLYIGSVWIPEYGNP+DPKDREFLLKYSPY
Sbjct: 481 LLVSATLTQRPDVMDSALIGYPVIDMLRFHKLYIGSVWIPEYGNPEDPKDREFLLKYSPY 540
Query: 541 HNVRP-QEYPPTLIYTGLHDDRVHPAHALKFFMKLKEVNAPVYLRVETKSGHMGASPETR 599
HNV P ++YPPTLIYTGLHDDRVHPAHALKFFMKLKE+ APVYLRVETKSGHMGASPETR
Sbjct: 541 HNVDPKKKYPPTLIYTGLHDDRVHPAHALKFFMKLKEIGAPVYLRVETKSGHMGASPETR 600
Query: 600 ARELTDLLAFVL 611
ARELTDLLAFVL
Sbjct: 601 ARELTDLLAFVL 612
>pir||B71071 probable prolyl endopeptidase - Pyrococcus horikoshii
>gi|3257681|dbj|BAA30364.1| (AP000005) 617aa long
hypothetical prolyl endopeptidase [Pyrococcus
horikoshii]
Length = 617
Score = 1106 bits (2830), Expect = 0.0
Identities = 513/615 (83%), Positives = 577/615 (93%), Gaps = 1/615 (0%)
Query: 1 MEDPYIWMENLQDERVLKIVEEENRRFRELVGELSDKLFPEVWEYFSQPSIGMARITKRG 60
+EDPYIWMENLQD RV +I+E EN++FRE +GELSDKLFPEVWEYFS P++ MA+ITKRG
Sbjct: 2 VEDPYIWMENLQDNRVREIIERENKKFREFIGELSDKLFPEVWEYFSIPTVTMAKITKRG 61
Query: 61 IIVSYSEKDRVTVRWLGGEVIVDSKELEKELNDEVLLQGFTTDEDGKRLAYSFSIGGSDE 120
IIVSY+EKDR +RWL G+VIVDSKE+E+E+ DEVLLQGFT D++G++LAYSFSIGG+DE
Sbjct: 62 IIVSYNEKDRSIIRWLDGDVIVDSKEIEREVGDEVLLQGFTADDEGEKLAYSFSIGGADE 121
Query: 121 GITRIIDLETGELLEEIKPSVWNIVFLDKGYYFARFYRKEKTPDGVNPPAERIFWKDEEG 180
GITRIIDL++GE++EEIKPS+WNI+FL GYYFARFYRKEKTPDGV+PPAER+FWKD+EG
Sbjct: 122 GITRIIDLKSGEVIEEIKPSIWNILFLKDGYYFARFYRKEKTPDGVDPPAERVFWKDKEG 181
Query: 181 ERMVFGEGLTSGYFMSLRKSTDGKFAMLTLTYGWNKAEIYLGPIDKPEEWKKVYSADVPA 240
E+MVFGEGLTSGYFM+LRKS+D KFAMLTL YGWN+ EIY+GPIDKP+EW+KVYSA VP
Sbjct: 182 EKMVFGEGLTSGYFMTLRKSSDDKFAMLTLNYGWNQGEIYVGPIDKPQEWRKVYSATVPV 241
Query: 241 EPIDVIDGKLYILTKEGKGLGKVIAVKDSEVEEIIPEGEFPLEWAVIVKDKILAGRLVHA 300
EP+D+++GKLYILT+EG+G+GKVIAVKD E+EE+IPEGEFPLEWAVIV DKI+AGRLVHA
Sbjct: 242 EPVDIVNGKLYILTREGRGMGKVIAVKDGEIEEVIPEGEFPLEWAVIVDDKIVAGRLVHA 301
Query: 301 SHKLEVYNLKGEKISEVEFDFPGSLYPLDKDDERALLRYTSFTVPYRIYEFKDELKIVEE 360
SH+LEVY LKGEKI EV FD PG+L+PLDK+++ LLRY SFT+PYR+YEFKD+L+I+EE
Sbjct: 302 SHRLEVYTLKGEKIEEVTFDIPGALHPLDKNNKEVLLRYISFTIPYRLYEFKDKLRIIEE 361
Query: 361 RKVEGNFKVEEDFAISKDGTRVHYFIVKGEKDEKKAWVFGYGGFNISLTPRFFPQVIPFL 420
RKVEG FKVEEDF +SKDGTR+HYFI+KGEKDEKKAWVFGYGGFNI+LTPRFFPQVIPFL
Sbjct: 362 RKVEGKFKVEEDFVVSKDGTRIHYFIIKGEKDEKKAWVFGYGGFNIALTPRFFPQVIPFL 421
Query: 421 KRGGIFVMANLRGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGYKVAAWGRSNGG 480
KRGG FVMANLRGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGYKVAAWGRSNGG
Sbjct: 422 KRGGTFVMANLRGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGYKVAAWGRSNGG 481
Query: 481 LLVSATLVQRPDVMDVALIGYPVIDMLRFHKLYIGSVWIPEYGNPDDPKDREFLLKYSPY 540
LLVSATL QRPD+MD ALIGYPVIDMLRFHKLYIGSVWIPEYGNPDDPKDREFLLKYSPY
Sbjct: 482 LLVSATLTQRPDIMDAALIGYPVIDMLRFHKLYIGSVWIPEYGNPDDPKDREFLLKYSPY 541
Query: 541 HNVRP-QEYPPTLIYTGLHDDRVHPAHALKFFMKLKEVNAPVYLRVETKSGHMGASPETR 599
HNV P ++YP TLIYTGLHDDRVHPAHALKFFMKLKEV APVYLRVETKSGHMGASPETR
Sbjct: 542 HNVDPNKKYPLTLIYTGLHDDRVHPAHALKFFMKLKEVGAPVYLRVETKSGHMGASPETR 601
Query: 600 ARELTDLLAFVLLHL 614
ARELTDLLAFVL L
Sbjct: 602 ARELTDLLAFVLKSL 616
>pir||B75267 prolyl endopeptidase - Deinococcus radiodurans (strain R1)
>gi|6460324|gb|AAF12044.1|AE002079_9 (AE002079) prolyl
endopeptidase [Deinococcus radiodurans]
Length = 686
Score = 286 bits (725), Expect = 4e-76
Identities = 217/672 (32%), Positives = 325/672 (48%), Gaps = 84/672 (12%)
Query: 3 DPYIWMENLQDERVLKIVEEENRRFRELVGELSDKL-----FPEVWEYFSQPSIGMA--- 54
DPY W+E+ + VE +N + + L + +W+Y P G+
Sbjct: 29 DPYRWLEDPDSPETRRWVEAQNAVTEDFLAALPARAAYRERLTALWDY---PRDGLPWER 85
Query: 55 -----RITKRGIIVSYSEKDRVTVRWLGGEVIVDSKELEKELNDEVLLQGFTTDEDGKRL 109
R G++ + + R E++ D L + V L G + +DG +L
Sbjct: 86 GGRYFRTFNPGLLNQPVLQTADSPRGPWHELL-DPNALSAD--GTVALMGASVSQDGTQL 142
Query: 110 AYSFSIGGSDEGITRIIDLETGELLEEIKPSVWN----IVFLDKGYYFARFYRKEKTPD- 164
AY+ GGSD ++ D+ +GE E P W+ +L G F FY P
Sbjct: 143 AYATQSGGSDWLTWQVRDVASGEDTGE--PLRWSKFSGAAWLPDGSGF--FYSAYDAPGE 198
Query: 165 -----GVNPPAERIFWK---DEEGERMVFGEGLTSGYFMSLRKSTDGKFAMLTLTYGWNK 216
G N +F + ++ + +V + + + DG W
Sbjct: 199 GEALTGANKNQRLMFHRLGTPQDADELVLERPDQPDWGFAAEVTEDG---------AWLA 249
Query: 217 AEIYLGPIDKPEEWKKVYSADVPAE--------------PIDVIDGK-LYILTKEGKGLG 261
+++LG K W + + P + DG L++ T E LG
Sbjct: 250 VQVWLGTSPKNLLWVRPLGKEGPGSGDFQPLVNDFQAMYQLVGSDGNTLFLQTDEDAPLG 309
Query: 262 KVIA--VKDSEVEEIIPEGEFPLEWAVIVKDKILAGRLVHASHKLEVYNLKGEKISEVEF 319
K++A ++ E +++PEG LE + V LA L ASH+L +Y+ GE+ E+E
Sbjct: 310 KLMAWNIRTGERRDLLPEGADKLEQVLTVPGGFLALTLHDASHRLTLYDRNGERQREIEL 369
Query: 320 DFPGSL-YPLDKDDERALLRYTSFTVPYRIYEFK---DELKIVEERKVE---GNFKVEED 372
G++ ++D + +TSF VP R Y K EL+ + + ++ ++V ++
Sbjct: 370 PALGTVSVSAEQDSSEVFVAFTSFLVPSRPYRLKLPGGELEPLADPALDFDAATYEVTQE 429
Query: 373 FAISKDGTRVHYFIVKGEKD-----EKKAWVFGYGGFNISLTPRFFPQVIPFLKRGGIFV 427
FA+SKDGTRV FIV KD + ++GYGGF+ISLTP F + +L+RGG+FV
Sbjct: 430 FAMSKDGTRVPMFIV-ARKDAPRDGSNRTLLYGYGGFSISLTPAFSASRLAWLERGGVFV 488
Query: 428 MANLRGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGY----KVAAWGRSNGGLLV 483
ANLRGG EYGE WH AG KQNVFDDF A E L ++G+ ++A G SNGGLLV
Sbjct: 489 QANLRGGGEYGEAWHEAGTLGRKQNVFDDFAACAEHLARQGWTRPERLAIQGGSNGGLLV 548
Query: 484 SATLVQRPDVMDVALIGYPVIDMLRFHKLYIGSVWIPEYGNPDDPKDREFLLKYSPYHNV 543
A++ QRP++ A+ V+DMLR+H IG W +YG DDP+ L YSP HN+
Sbjct: 549 GASITQRPELFGAAVAQVGVLDMLRYHLFTIGWAWASDYGRSDDPEMFATLHAYSPLHNL 608
Query: 544 RP-QEYPPTLIYTGLHDDRVHPAHALKFFMKLKEV---NAPVYLRVETKSGHMGASPETR 599
+ YP TLI TG HDDRV PAH+ KF +L+ V +AP +R++T++GH P
Sbjct: 609 KEGTRYPATLITTGDHDDRVVPAHSYKFAAELQRVQAGSAPTLIRIQTRAGHGAGKPTAL 668
Query: 600 A-RELTDLLAFV 610
E D+ AF+
Sbjct: 669 VIEEAADIWAFL 680
>gb|AAD31004.1|AF127082_3 (AF127082) prolyl endopeptidase precursor Pep [Myxococcus xanthus]
Length = 689
Score = 263 bits (666), Expect = 3e-69
Identities = 204/665 (30%), Positives = 321/665 (47%), Gaps = 72/665 (10%)
Query: 3 DPYIWMENLQDERVLKIVEEENRRFRELVGELSDK-----LFPEVWEYFSQPSIGMARIT 57
DPY W+E+ + V + +N RE + + + F E++ Y S R
Sbjct: 22 DPYRWLEDEKAPEVQTWMTAQNAHAREALAKFPGREALAARFKELF-YTDSVSTPSRRNG 80
Query: 58 KRGIIVSYSEKDRVTVRWLGGE-----VIVDSKELEKELNDEVLLQGFTTDEDGKRLAYS 112
+ + ++ +K++ + W GE V++D K+ V L + DGK++A++
Sbjct: 81 RFFYVRTHKDKEKAILYWRQGESGQEKVLLDPNGWSKD--GTVSLGTWAVSWDGKKVAFA 138
Query: 113 FSIGGSDEGITRIIDLETGE-----LLEEIKPSVWNIVFLDKGYYFARFYRKEKTPDGVN 167
+DE + +ID+++GE ++E K + KG+Y+
Sbjct: 139 QKPNAADEAVLHVIDVDSGEWSKVDVIEGGKYATPKWTPDSKGFYYEWLPTDPSIKVDER 198
Query: 168 PPAERIFWK----DEEGERMVFGEGLTSGYFMSLRKSTDGKFAMLTLTYGWNKAEIYLGP 223
P I + + + +V F+ S DGK+ + + GW++ ++Y
Sbjct: 199 PGYTTIRYHTLGTEPSKDTVVHERTGDPTTFLQSDLSRDGKYLFVYILRGWSENDVY--- 255
Query: 224 IDKPEEWKKVYSAD-------VPAE-PIDVIDGKLYILTKEGKGLGKVIAVKDSEV---- 271
WK+ D V A+ + + Y+LT EG +V V ++
Sbjct: 256 ------WKRPGEKDFRLLVKGVGAKYEVHAWKDRFYVLTDEGAPRQRVFEVDPAKPARAS 309
Query: 272 -EEIIPEGEFPLEWAV-IVKDKILAGRLVHASHKLEVYNLKGEKISEVEFDFPGSLYPL- 328
+EI+PE +V IV + L A+ ++ V LKG+ + V+ G+ L
Sbjct: 310 WKEIVPEDSSASLLSVSIVGGHLSLEYLKDATSEVRVATLKGKPVRTVQLPGVGAASNLM 369
Query: 329 ---DKDDERALLRYTSFTVPYRIYEF-----KDELKI-VEERKVEGNFKVEEDFAISKDG 379
D DD A +TSFT P +IY+ K EL V+ ++VE+ F SKDG
Sbjct: 370 GLEDLDD--AYYVFTSFTTPRQIYKTSVSTGKSELWAKVDVPMNPEQYQVEQVFYASKDG 427
Query: 380 TRVHYFIVKGEKDEKK-----AWVFGYGGFNISLTPRFFPQVIPFLKRGGIFVMANLRGG 434
T+V F+V KD K+ ++GYGGFN+++ F ++P+L GG++ +ANLRGG
Sbjct: 428 TKVPMFVVH-RKDLKRDGNAPTLLYGYGGFNVNMEANFRSSILPWLDAGGVYAVANLRGG 486
Query: 435 SEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGY----KVAAWGRSNGGLLVSATLVQR 490
EYG+ WH AG + KQNVFDDF A E L ++ Y ++A +G SNGGLLV A + QR
Sbjct: 487 GEYGKAWHDAGRLDKKQNVFDDFHAAAEYLVQQKYTQPKRLAIYGGSNGGLLVGAAMTQR 546
Query: 491 PDVMDVALIGYPVIDMLRFHKLYIGSVWIPEYGNPDDPKDREFLLKYSPYHNVRPQ-EYP 549
P++ + P++DM+R+H G WIPEYG + P+D + L YSPYH+VRP YP
Sbjct: 547 PELYGAVVCAVPLLDMVRYHLFGSGRTWIPEYGTAEKPEDFKTLHAYSPYHHVRPDVRYP 606
Query: 550 PTLIYTGLHDDRVHPAHALKFFMKLKEV---NAPVYLRVETKSGHMGASPETRARELT-D 605
L+ HDDRV P HA KF ++ A LR+E +GH GA +A E + D
Sbjct: 607 ALLMMAADHDDRVDPMHARKFVAAVQNSPGNPATALLRIEANAGHGGADQVAKAIESSVD 666
Query: 606 LLAFV 610
L +F+
Sbjct: 667 LYSFL 671
>gb|AAD34991.1| (AF143951) prolyl endopeptidase [Aeromonas punctata subsp.
punctata]
Length = 690
Score = 254 bits (642), Expect = 2e-66
Identities = 181/583 (31%), Positives = 295/583 (50%), Gaps = 60/583 (10%)
Query: 79 EVIVDSKELEKELNDEVLLQGFTTDEDGKRLAYSFSIGGSDEGITRIIDLETGELLE--- 135
EV +D L + L + DG+ LAYS S+ GSD ++D+E+ + LE
Sbjct: 112 EVFLDPNTLSPD--GTTALDQLSFSRDGRILAYSLSLAGSDWREIHLMDVESKQPLETPL 169
Query: 136 -EIKPSVWNIVFL-DKGYYFARFYRKEKTPDGVNPPAERIFWKD----EEGERMVFGEGL 189
++K S I +L ++G++++ + + + + ++++ +E +R+VFG
Sbjct: 170 KDVKFS--GISWLGNEGFFYSSYDKPDGSELSARTDQHKVYFHRLGTAQEDDRLVFGAIP 227
Query: 190 TSGY-FMSLRKSTDGKFAMLTLTYGWNKAEIYLGPIDKPEEWKKVYSADVPAEPIDVIDG 248
+ ++ + D +F +++ + +Y+ + + D+ A+ + ++D
Sbjct: 228 AQHHRYVGATVTEDDRFLLISAANSTSGNRLYVKDLSQENAPLLTVQGDLDAD-VSLVDN 286
Query: 249 K---LYILTKEGKGLGKVIAVKDSEVEEIIPEGEFPLEWAVIVKDK------------IL 293
K LY+LT +++ V + P W ++ ++ +
Sbjct: 287 KGSTLYLLTNRDAPNRRLVTVDAANPG--------PAHWRDLIPERHRVLTVHSGTAYLF 338
Query: 294 AGRLVHASHKLEVYNLKGEKISEVEFDFPGSLYPLD--KDDERALLRYTSFTVPYRIYEF 351
A +V A+ +E ++ +G+++ EV GS+ + DD + ++ P +Y F
Sbjct: 339 AEYMVDATAPVEQFDYEGKRVREVALPGLGSVSGFNGKHDDPALYFGFENYAQPPTLYRF 398
Query: 352 KDELKIVEERKVEG------NFKVEEDFAISKDGTRVHYFIV--KGEK--DEKKAWVFGY 401
+ + + + ++ E+ F SKDGTRV I KG K ++GY
Sbjct: 399 EPKSGAISLYRASAAPFKPEDYVSEQRFYQSKDGTRVPLIISYRKGLKLDGSNPTILYGY 458
Query: 402 GGFNISLTPRFFPQVIPFLKRGGIFVMANLRGGSEYGEEWHRAGMRENKQNVFDDFIAVL 461
GGF++SLTP F V +L GG++ +ANLRGG EYG+ WH AG ++NKQNVFDDFIA
Sbjct: 459 GGFDVSLTPSFSVSVANWLDLGGVYAVANLRGGGEYGQAWHLAGTQQNKQNVFDDFIAAA 518
Query: 462 EKLKKEGY----KVAAWGRSNGGLLVSATLVQRPDVMDVALIGYPVIDMLRFHKLYIGSV 517
E LK EGY ++A G SNGGLLV A + QRPD+M VAL V+DMLR+H G+
Sbjct: 519 EYLKAEGYTRTDRLAIRGGSNGGLLVGAVMTQRPDLMRVALPAVGVLDMLRYHTFTAGAG 578
Query: 518 WIPEYGNPDDPKDR-EFLLKYSPYHNVRP-QEYPPTLIYTGLHDDRVHPAHALKFFMKLK 575
W +YG D + ++L YSP HNVRP YP T++ T HDDRV PAH+ KF L+
Sbjct: 579 WAYDYGTSADSEAMFDYLKGYSPLHNVRPGVSYPSTMVTTADHDDRVVPAHSFKFAATLQ 638
Query: 576 EVNA---PVYLRVETKSGHMGASPETRARELT-DLLAFVLLHL 614
NA P +R+ET +GH +P + E + D+ AF L +
Sbjct: 639 ADNAGPHPQLIRIETNAGHGAGTPVAKLIEQSADIYAFTLYEM 681
>gb|AAF02211.1| (AF065429) prolyl endopeptidase [Aeromonas punctata subsp.
punctata]
Length = 690
Score = 253 bits (640), Expect = 4e-66
Identities = 181/583 (31%), Positives = 294/583 (50%), Gaps = 60/583 (10%)
Query: 79 EVIVDSKELEKELNDEVLLQGFTTDEDGKRLAYSFSIGGSDEGITRIIDLETGELLE--- 135
EV +D L + L + DG+ LAYS S+ GSD ++D+E+ + LE
Sbjct: 112 EVFLDPNTLSPD--GTTALDQLSFSRDGRILAYSLSLAGSDWREIHLMDVESKQPLETPL 169
Query: 136 -EIKPSVWNIVFL-DKGYYFARFYRKEKTPDGVNPPAERIFWKD----EEGERMVFGEGL 189
++K S I +L ++G++++ + + + + ++++ +E +R+VFG
Sbjct: 170 KDVKFS--GISWLGNEGFFYSSYDKPDGSELSARTDQHKVYFHRLGTAQEDDRLVFGAIP 227
Query: 190 TSGY-FMSLRKSTDGKFAMLTLTYGWNKAEIYLGPIDKPEEWKKVYSADVPAEPIDVIDG 248
+ ++ + D +F +++ + +Y+ + + D+ A+ + ++D
Sbjct: 228 AQHHRYVGATVTEDDRFLLISAANSTSGNRLYVKDLSQENAPLLTVQGDLDAD-VSLVDN 286
Query: 249 K---LYILTKEGKGLGKVIAVKDSEVEEIIPEGEFPLEWAVIVKDK------------IL 293
K LY+LT +++ V + P W ++ ++ +
Sbjct: 287 KGSTLYLLTNRDAPNRRLVTVDAANPG--------PAHWRDLIPERHRVLTVHSGSGYLF 338
Query: 294 AGRLVHASHKLEVYNLKGEKISEVEFDFPGSLYPLD--KDDERALLRYTSFTVPYRIYEF 351
A +V A+ +E ++ +G+++ EV GS+ + DD + ++ P +Y F
Sbjct: 339 AEYMVDATAPVEQFDYEGKRVREVALPGLGSVSGFNGKHDDPALYFGFENYAQPPTLYRF 398
Query: 352 KDELKIVEERKVEG------NFKVEEDFAISKDGTRVHYFIV--KGEK--DEKKAWVFGY 401
+ + + ++ E+ F SKDGTRV I KG K ++GY
Sbjct: 399 EPKSGAISLYSASAAPFKPEDYVSEQRFYQSKDGTRVPLIISYRKGLKLDGSNPTILYGY 458
Query: 402 GGFNISLTPRFFPQVIPFLKRGGIFVMANLRGGSEYGEEWHRAGMRENKQNVFDDFIAVL 461
GGF++SLTP F V +L GG++ +ANLRGG EYG+ WH AG ++NKQNVFDDFIA
Sbjct: 459 GGFDVSLTPSFSVSVANWLDLGGVYAVANLRGGGEYGQAWHLAGTQQNKQNVFDDFIAAA 518
Query: 462 EKLKKEGY----KVAAWGRSNGGLLVSATLVQRPDVMDVALIGYPVIDMLRFHKLYIGSV 517
E LK EGY ++A G SNGGLLV A + QRPD+M VAL V+DMLR+H G+
Sbjct: 519 EYLKAEGYTRTDRLAIRGGSNGGLLVGAVMTQRPDLMRVALPAVGVLDMLRYHTFTAGAG 578
Query: 518 WIPEYGNPDDPKDR-EFLLKYSPYHNVRP-QEYPPTLIYTGLHDDRVHPAHALKFFMKLK 575
W +YG D + ++L YSP HNVRP YP T++ T HDDRV PAH+ KF L+
Sbjct: 579 WAYDYGTSADSEAMFDYLKGYSPLHNVRPGVSYPSTMVTTADHDDRVVPAHSFKFAATLQ 638
Query: 576 EVNA---PVYLRVETKSGHMGASPETRARELT-DLLAFVLLHL 614
NA P +R+ET +GH +P + E + D+ AF L +
Sbjct: 639 ADNAGPHPQLIRIETNAGHGAGTPVAKLIEQSADIYAFTLYEM 681
>pdb|1QFM|A Chain A, Prolyl Oligopeptidase From Porcine Muscle
Length = 710
Score = 249 bits (630), Expect = 5e-65
Identities = 208/690 (30%), Positives = 331/690 (47%), Gaps = 97/690 (14%)
Query: 3 DPYIWMENLQDERVLKIVEEENR-------------RFRELVGELSDKL-----FPEVWE 44
DPY W+E+ E+ VE +N+ ++E + EL D F +
Sbjct: 26 DPYAWLEDPDSEQTKAFVEAQNKITVPFLEQXPIRGLYKERMTELYDYPKYSCHFKKGKR 85
Query: 45 YFSQPSIGMARITKRGIIVSYSEKDRVTVRWLGGEVIVDSKELEKELNDEVLLQGFTTDE 104
YF + G+ +R + V S + V +L ++ D + V L+G+ E
Sbjct: 86 YFYFYNTGLQN--QRVLYVQDSLEGEARV-FLDPNILSD--------DGTVALRGYAFSE 134
Query: 105 DGKRLAYSFSIGGSDEGITRIIDL----ETGELLEEIKPSVWNIVFLDKGYYFARFYRKE 160
DG+ AY S GSD + + + E ++LE +K S KG ++ + +++
Sbjct: 135 DGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFSXMAWTHDGKGMFYNAYPQQD 194
Query: 161 KTPDGVNPPA---ERIFWK---DEEGERMVFGEGLTSGYFMS-LRKSTDGKFAMLTLTYG 213
DG +++++ ++ E ++ E +M S DG++ +L++ G
Sbjct: 195 GKSDGTETSTNLHQKLYYHVLGTDQSEDILCAEFPDEPKWMGGAELSDDGRYVLLSIREG 254
Query: 214 WNKAEIYLGPIDKPEEWKKVYSADVPAEPIDVIDGKLYILTKEGKGLG----------KV 263
+ L D +E + + ID +G+ +T EG ++
Sbjct: 255 XDPVN-RLWYCDLQQESNGITGILKWVKLIDNFEGEYDYVTNEGTVFTFKTNRHSPNYRL 313
Query: 264 IAVKDSEVEE-----IIPEGEFP-LEWAVIVKDKILAGRLVH-ASHKLEVYNLKGEKISE 316
I + ++ EE ++PE E LEW V+ L +H + L++++L + +
Sbjct: 314 INIDFTDPEESKWKVLVPEHEKDVLEWVACVRSNFLVLCYLHDVKNTLQLHDLATGALLK 373
Query: 317 VEFDFP---GSL--YPLDKDDERALLRYTSFTVPYRIYEF---KDEL--KIVEERKVEG- 365
+ FP GS+ Y K D ++TSF P IY K+EL ++ E V+G
Sbjct: 374 I---FPLEVGSVVGYSGQKKDTEIFYQFTSFLSPGIIYHCDLTKEELEPRVFREVTVKGI 430
Query: 366 ---NFKVEEDFAISKDGTRVHYFIV--KGEK--DEKKAWVFGYGGFNISLTPRFFPQVIP 418
+++ + F SKDGT++ FIV KG K A+++GYGGFNIS+TP + +
Sbjct: 431 DASDYQTVQIFYPSKDGTKIPMFIVHKKGIKLDGSHPAFLYGYGGFNISITPNYSVSRLI 490
Query: 419 FLKR-GGIFVMANLRGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGY----KVAA 473
F++ GG+ +AN+RGG EYGE WH+ G+ NKQN FDDF E L KEGY ++
Sbjct: 491 FVRHMGGVLAVANIRGGGEYGETWHKGGILANKQNCFDDFQCAAEYLIKEGYTSPKRLTI 550
Query: 474 WGRSNGGLLVSATLVQRPDVMDVALIGYPVIDMLRFHKLYIGSVWIPEYGNPDDPKDREF 533
G SNGGLLV+ QRPD+ + V+DML+FHK IG W +YG D + E+
Sbjct: 551 NGGSNGGLLVATCANQRPDLFGCVIAQVGVMDMLKFHKYTIGHAWTTDYGXSDSKQHFEW 610
Query: 534 LLKYSPYHNVRPQE-----YPPTLIYTGLHDDRVHPAHALKFFMKLKEV-------NAPV 581
L+KYSP HNV+ E YP L+ T HDDRV P H+LKF L+ + N P+
Sbjct: 611 LIKYSPLHNVKLPEADDIQYPSMLLLTADHDDRVVPLHSLKFIATLQYIVGRSRKQNNPL 670
Query: 582 YLRVETKSGHMGASPETRA-RELTDLLAFV 610
+ V+TK+GH P + E++D+ AF+
Sbjct: 671 LIHVDTKAGHGAGKPTAKVIEEVSDMFAFI 700
>sp|P23687|PPCE_PIG PROLYL ENDOPEPTIDASE (POST-PROLINE CLEAVING ENZYME) (PE)
>gi|108383|pir||A37942 prolyl oligopeptidase (EC
3.4.21.26) - pig >gi|5107663|pdb|1QFS|A Chain A, Prolyl
Oligopeptidase From Porcine Muscle With Covalently Bound
Inhibitor Z-Pro-Prolinal >gi|164621|gb|AAA31110.1|
(M64227) prolyl endopeptidase [Sus scrofa]
Length = 710
Score = 249 bits (628), Expect = 9e-65
Identities = 208/690 (30%), Positives = 331/690 (47%), Gaps = 97/690 (14%)
Query: 3 DPYIWMENLQDERVLKIVEEENR-------------RFRELVGELSDKL-----FPEVWE 44
DPY W+E+ E+ VE +N+ ++E + EL D F +
Sbjct: 26 DPYAWLEDPDSEQTKAFVEAQNKITVPFLEQCPIRGLYKERMTELYDYPKYSCHFKKGKR 85
Query: 45 YFSQPSIGMARITKRGIIVSYSEKDRVTVRWLGGEVIVDSKELEKELNDEVLLQGFTTDE 104
YF + G+ +R + V S + V +L ++ D + V L+G+ E
Sbjct: 86 YFYFYNTGLQN--QRVLYVQDSLEGEARV-FLDPNILSD--------DGTVALRGYAFSE 134
Query: 105 DGKRLAYSFSIGGSDEGITRIIDL----ETGELLEEIKPSVWNIVFLDKGYYFARFYRKE 160
DG+ AY S GSD + + + E ++LE +K S KG ++ + +++
Sbjct: 135 DGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFSCMAWTHDGKGMFYNAYPQQD 194
Query: 161 KTPDGVNPPA---ERIFWK---DEEGERMVFGEGLTSGYFMS-LRKSTDGKFAMLTLTYG 213
DG +++++ ++ E ++ E +M S DG++ +L++ G
Sbjct: 195 GKSDGTETSTNLHQKLYYHVLGTDQSEDILCAEFPDEPKWMGGAELSDDGRYVLLSIREG 254
Query: 214 WNKAEIYLGPIDKPEEWKKVYSADVPAEPIDVIDGKLYILTKEGKGLG----------KV 263
+ L D +E + + ID +G+ +T EG ++
Sbjct: 255 CDPVN-RLWYCDLQQESNGITGILKWVKLIDNFEGEYDYVTNEGTVFTFKTNRHSPNYRL 313
Query: 264 IAVKDSEVEE-----IIPEGEFP-LEWAVIVKDKILAGRLVH-ASHKLEVYNLKGEKISE 316
I + ++ EE ++PE E LEW V+ L +H + L++++L + +
Sbjct: 314 INIDFTDPEESKWKVLVPEHEKDVLEWVACVRSNFLVLCYLHDVKNTLQLHDLATGALLK 373
Query: 317 VEFDFP---GSL--YPLDKDDERALLRYTSFTVPYRIYEF---KDEL--KIVEERKVEG- 365
+ FP GS+ Y K D ++TSF P IY K+EL ++ E V+G
Sbjct: 374 I---FPLEVGSVVGYSGQKKDTEIFYQFTSFLSPGIIYHCDLTKEELEPRVFREVTVKGI 430
Query: 366 ---NFKVEEDFAISKDGTRVHYFIV--KGEK--DEKKAWVFGYGGFNISLTPRFFPQVIP 418
+++ + F SKDGT++ FIV KG K A+++GYGGFNIS+TP + +
Sbjct: 431 DASDYQTVQIFYPSKDGTKIPMFIVHKKGIKLDGSHPAFLYGYGGFNISITPNYSVSRLI 490
Query: 419 FLKR-GGIFVMANLRGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGY----KVAA 473
F++ GG+ +AN+RGG EYGE WH+ G+ NKQN FDDF E L KEGY ++
Sbjct: 491 FVRHMGGVLAVANIRGGGEYGETWHKGGILANKQNCFDDFQCAAEYLIKEGYTSPKRLTI 550
Query: 474 WGRSNGGLLVSATLVQRPDVMDVALIGYPVIDMLRFHKLYIGSVWIPEYGNPDDPKDREF 533
G SNGGLLV+ QRPD+ + V+DML+FHK IG W +YG D + E+
Sbjct: 551 NGGSNGGLLVATCANQRPDLFGCVIAQVGVMDMLKFHKYTIGHAWTTDYGCSDSKQHFEW 610
Query: 534 LLKYSPYHNVRPQE-----YPPTLIYTGLHDDRVHPAHALKFFMKLKEV-------NAPV 581
L+KYSP HNV+ E YP L+ T HDDRV P H+LKF L+ + N P+
Sbjct: 611 LIKYSPLHNVKLPEADDIQYPSMLLLTADHDDRVVPLHSLKFIATLQYIVGRSRKQNNPL 670
Query: 582 YLRVETKSGHMGASPETRA-RELTDLLAFV 610
+ V+TK+GH P + E++D+ AF+
Sbjct: 671 LIHVDTKAGHGAGKPTAKVIEEVSDMFAFI 700
>gi|4506043 prolyl endopeptidase [Homo sapiens]
>gi|1346769|sp|P48147|PPCE_HUMAN PROLYL ENDOPEPTIDASE
(POST-PROLINE CLEAVING ENZYME) (PE)
>gi|7435602|pir||I38134 prolyl oligopeptidase - human
>gi|558596|emb|CAA52605.1| (X74496) prolyl
oligopeptidase [Homo sapiens] >gi|1585155|prf||2124300A
Pro oligopeptidase [Homo sapiens]
Length = 710
Score = 247 bits (624), Expect = 3e-64
Identities = 209/688 (30%), Positives = 331/688 (47%), Gaps = 93/688 (13%)
Query: 3 DPYIWMENLQDERVLKIVEEENR-------------RFRELVGELSDKL-----FPEVWE 44
DPY W+E+ E+ VE +N+ ++E + EL D F +
Sbjct: 26 DPYAWLEDPDSEQTKAFVEAQNKITVPFLEQCPIRGLYKERMTELYDYPKYSCHFKKGKR 85
Query: 45 YFSQPSIGMARITKRGIIVSYSEKDRVTVRWLGGEVIVDSKELEKELNDEVLLQGFTTDE 104
YF + G+ +R + V S + V +L ++ D + V L+G+ E
Sbjct: 86 YFYFYNTGLQN--QRVLYVQDSLEGEARV-FLDPNILSD--------DGTVALRGYAFSE 134
Query: 105 DGKRLAYSFSIGGSDEGITRIIDL----ETGELLEEIKPSVWNIVFLDKGYYFARFYRKE 160
DG+ AY S GSD + + + E ++LE +K S KG ++ + +++
Sbjct: 135 DGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFSCMAWTHDGKGMFYNSYPQQD 194
Query: 161 KTPDGVNPPA---ERIFWK---DEEGERMVFGEGLTSGYFMS-LRKSTDGKFAMLTLTYG 213
DG +++++ ++ E ++ E +M S DG++ +L++ G
Sbjct: 195 GKSDGTETSTNLHQKLYYHVLGTDQSEDILCAEFPDEPKWMGGAELSDDGRYVLLSIREG 254
Query: 214 WNKAEIYLGPIDKPEEWKKVYSADVPAEPIDVIDGKLYILTKEGKGLG----------KV 263
+ L D +E + + ID +G+ +T EG +V
Sbjct: 255 CDPVN-RLWYCDLQQESSGIAGILKWVKLIDNFEGEYDYVTNEGTVFTFKTNRQSPNYRV 313
Query: 264 IAV-----KDSEVEEIIPEGEFP-LEWAVIVKDKILAGRLVH-ASHKLEVYNLK-GEKIS 315
I + ++S+ + ++PE E LEW V+ L +H + L++++L G +
Sbjct: 314 INIDFWDPEESKWKVLVPEHEKDVLEWIACVRSNFLVLCYLHDVKNILQLHDLTTGALLK 373
Query: 316 EVEFDFPGSL--YPLDKDDERALLRYTSFTVPYRIYEF---KDEL--KIVEERKVEG--- 365
D GS+ Y K D ++TSF P IY K+EL ++ E V+G
Sbjct: 374 TFPLDV-GSIVGYSGQKKDTEIFYQFTSFLSPGIIYHCDLTKEELEPRVFREVTVKGIDA 432
Query: 366 -NFKVEEDFAISKDGTRVHYFIV--KGEK--DEKKAWVFGYGGFNISLTPRFFPQVIPFL 420
+++ + F SKDGT++ FIV KG K A+++GYGGFNIS+TP + + F+
Sbjct: 433 SDYQTVQIFYPSKDGTKIPMFIVHKKGIKLDGSHPAFLYGYGGFNISITPNYSVSRLIFV 492
Query: 421 KR-GGIFVMANLRGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGY----KVAAWG 475
+ GGI +AN+RGG EYGE WH+ G+ NKQN FDDF E L KEGY ++ G
Sbjct: 493 RHMGGILAVANIRGGGEYGETWHKGGILANKQNCFDDFQCAAEYLIKEGYTSPKRLTING 552
Query: 476 RSNGGLLVSATLVQRPDVMDVALIGYPVIDMLRFHKLYIGSVWIPEYGNPDDPKDREFLL 535
SNGGLLV+A QRPD+ + V+DML+FHK IG W +YG D + E+L+
Sbjct: 553 GSNGGLLVAACANQRPDLFGCVIAQVGVMDMLKFHKYTIGHAWTTDYGCSDSKQHFEWLV 612
Query: 536 KYSPYHNVRPQE-----YPPTLIYTGLHDDRVHPAHALKFFMKLKEV-------NAPVYL 583
KYSP HNV+ E YP L+ T HDDRV P H+LKF L+ + + P+ +
Sbjct: 613 KYSPLHNVKLPEADDIQYPSMLLLTADHDDRVVPLHSLKFIATLQYIVGRSRKQSNPLLI 672
Query: 584 RVETKSGHMGASPETRA-RELTDLLAFV 610
V+TK+GH P + E++D+ AF+
Sbjct: 673 HVDTKAGHGAGKPTAKVIEEVSDMFAFI 700
>pdb|1E5T|A Chain A, Prolyl Oligopeptidase From Porcine Brain, Mutant
Length = 710
Score = 247 bits (623), Expect = 4e-64
Identities = 208/690 (30%), Positives = 330/690 (47%), Gaps = 97/690 (14%)
Query: 3 DPYIWMENLQDERVLKIVEEENR-------------RFRELVGELSDKL-----FPEVWE 44
DPY W+E+ E+ VE +N+ ++E + EL D F +
Sbjct: 26 DPYAWLEDPDSEQTKAFVEAQNKITVPFLEQCPIRGLYKERMTELYDYPKYSCHFKKGKR 85
Query: 45 YFSQPSIGMARITKRGIIVSYSEKDRVTVRWLGGEVIVDSKELEKELNDEVLLQGFTTDE 104
YF + G+ +R + V S + V +L ++ D + V L+G+ E
Sbjct: 86 YFYFYNTGLQN--QRVLYVQDSLEGEARV-FLDPNILSD--------DGTVALRGYAFSE 134
Query: 105 DGKRLAYSFSIGGSDEGITRIIDL----ETGELLEEIKPSVWNIVFLDKGYYFARFYRKE 160
DG+ AY S GSD + + + E ++LE +K S KG ++ + +++
Sbjct: 135 DGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFSCMAWTHDGKGMFYNAYPQQD 194
Query: 161 KTPDGVNPPA---ERIFWK---DEEGERMVFGEGLTSGYFMS-LRKSTDGKFAMLTLTYG 213
DG +++++ ++ E ++ E +M S DG++ +L++ G
Sbjct: 195 GKSDGTETSTNLHQKLYYHVLGTDQSEDILCAEFPDEPKWMGGAELSDDGRYVLLSIREG 254
Query: 214 WNKAEIYLGPIDKPEEWKKVYSADVPAEPIDVIDGKLYILTKEGKGLG----------KV 263
+ L D +E + + ID +G+ +T EG ++
Sbjct: 255 TDPVN-RLWYCDLQQESNGITGILKWVKLIDNFEGEYDYVTNEGTVFTFKTNRHSPNYRL 313
Query: 264 IAVKDSEVEE-----IIPEGEFP-LEWAVIVKDKILAGRLVH-ASHKLEVYNLKGEKISE 316
I + ++ EE ++PE E LEW V+ L +H + L++++L + +
Sbjct: 314 INIDFTDPEESKWKVLVPEHEKDVLEWVACVRSNFLVLCYLHDVKNTLQLHDLATGALLK 373
Query: 317 VEFDFP---GSL--YPLDKDDERALLRYTSFTVPYRIYEF---KDEL--KIVEERKVEG- 365
+ FP GS+ Y K D +TSF P IY K+EL ++ E V+G
Sbjct: 374 I---FPLEVGSVVGYSGQKKDTEIFYCFTSFLSPGIIYHCDLTKEELEPRVFREVTVKGI 430
Query: 366 ---NFKVEEDFAISKDGTRVHYFIV--KGEK--DEKKAWVFGYGGFNISLTPRFFPQVIP 418
+++ + F SKDGT++ FIV KG K A+++GYGGFNIS+TP + +
Sbjct: 431 DASDYQTVQIFYPSKDGTKIPMFIVHKKGIKLDGSHPAFLYGYGGFNISITPNYSVSRLI 490
Query: 419 FLKR-GGIFVMANLRGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGY----KVAA 473
F++ GG+ +AN+RGG EYGE WH+ G+ NKQN FDDF E L KEGY ++
Sbjct: 491 FVRHMGGVLAVANIRGGGEYGETWHKGGILANKQNCFDDFQCAAEYLIKEGYTSPKRLTI 550
Query: 474 WGRSNGGLLVSATLVQRPDVMDVALIGYPVIDMLRFHKLYIGSVWIPEYGNPDDPKDREF 533
G SNGGLLV+ QRPD+ + V+DML+FHK IG W +YG D + E+
Sbjct: 551 NGGSNGGLLVATCANQRPDLFGCVIAQVGVMDMLKFHKYTIGHAWTTDYGCSDSKQHFEW 610
Query: 534 LLKYSPYHNVRPQE-----YPPTLIYTGLHDDRVHPAHALKFFMKLKEV-------NAPV 581
L+KYSP HNV+ E YP L+ T HDDRV P H+LKF L+ + N P+
Sbjct: 611 LIKYSPLHNVKLPEADDIQYPSMLLLTADHDDRVVPLHSLKFIATLQYIVGRSRKQNNPL 670
Query: 582 YLRVETKSGHMGASPETRA-RELTDLLAFV 610
+ V+TK+GH P + E++D+ AF+
Sbjct: 671 LIHVDTKAGHGAGMPTAKVIEEVSDMFAFI 700
>pir||JN0585 prolyl oligopeptidase (EC 3.4.21.26) - Aeromonas hydrophila
(strain JM83)
Length = 689
Score = 246 bits (622), Expect = 5e-64
Identities = 192/667 (28%), Positives = 322/667 (47%), Gaps = 68/667 (10%)
Query: 3 DPYIWMENLQDERVLKIVEEENRRFRELVGELSDK-----LFPEVWEYFSQPSIGMARIT 57
DPY W+E+ + V+ +NR ++ + ++ + W Y + +
Sbjct: 27 DPYRWLEDDRSPETEAWVKAQNRVTQDYLAQIPFRDAIKGKLATSWNYAKEGAPFREGRY 86
Query: 58 KRGIIVSYSEKDRVTVRWLGG---EVIVDSKELEKELNDEVLLQGFTTDEDGKRLAYSFS 114
+ V L G EV +D L + L + DGK LAYS S
Sbjct: 87 HYFFKNDGLQNQNVLCGQLAGKPAEVFLDPNLLSPD--GTTALDQLSFSRDGKTLAYSLS 144
Query: 115 IGGSDEGITRIIDLETGELLE----EIKPSVWNIVFL-DKGYYFARFYRKEKTPDGVNPP 169
+ GSD ++D+E+ + LE ++K S I +L ++G++++ + + + +
Sbjct: 145 LAGSDWREIHLMDVESKQPLETPLRDVKFS--GISWLGNEGFFYSSYDKPDGSELSARTD 202
Query: 170 AERIFWKD----EEGERMVFGEGLTSGY-FMSLRKSTDGKFAMLTLTYGWNKAEIYLGPI 224
++++ +E +R+VFG + ++ + D ++ +++ + +Y+ +
Sbjct: 203 QHKLYFHRLGTAQEEDRLVFGAIPAQRHRYVGATVTEDDRYLLISAADSTSGNRLYVKDL 262
Query: 225 DKPEEWKKVYSADVPAEPIDVIDGK---LYILTKEGKGLGKVIAVKDSEVEEIIPEGEFP 281
+ D+ A+ + ++D K LY+LT +++ V+ + P
Sbjct: 263 TREGAPLLTVQGDLAAD-VSLVDNKGSRLYLLTNRDAPNRRLVTVE--------ADNPGP 313
Query: 282 LEWAVIVKDK------------ILAGRLVHASHKLEVYNLKGEKISEVEFDFPGSLYPLD 329
+W ++ ++ + A +V A+ ++E ++ G+++ EV GS+ +
Sbjct: 314 EQWRDLIPERQQVLTVHSGGGYLFAEYMVDATARVEQFDHDGKRVREVGLPGLGSVSGFN 373
Query: 330 --KDDERALLRYTSFTVPYRIYEFKDELKIVEERKVEG------NFKVEEDFAISKDGTR 381
+DD + ++ P +Y+F+ + + ++ E+ F SKDGTR
Sbjct: 374 GKQDDPALYFGFENYAQPPTLYKFEPNSGAISLYRASAAPFKPEDYVSEQRFYRSKDGTR 433
Query: 382 VHYFIV--KGEK--DEKKAWVFGYGGFNISLTPRFFPQVIPFLKRGGIFVMANLRGGSEY 437
V I KG K ++GYGGF++SLTP F V +L GG++ +ANLRGG EY
Sbjct: 434 VPLIISYRKGLKLDGSNPTILYGYGGFDVSLTPSFSVSVANWLDLGGVYAVANLRGGGEY 493
Query: 438 GEEWHRAGMRENKQNVFDDFIAVLEKLKKEGY----KVAAWGRSNGGLLVSATLVQRPDV 493
G+ WH AG R NKQNVFDDFIA E LK EGY ++A G SNGGLLV A + QRPD+
Sbjct: 494 GQAWHLAGTRMNKQNVFDDFIAAAEYLKAEGYTRTDRLAIRGGSNGGLLVGAVMTQRPDL 553
Query: 494 MDVALIGYPVIDMLRFHKLYIGSVWIPEYGNPDDPKDR-EFLLKYSPYHNVRP-QEYPPT 551
M VA V+DMLR+H G+ W +YG D + ++L YSP H+VR YP T
Sbjct: 554 MRVACQAVGVLDMLRYHTFTAGAGWAYDYGTSADSEAMFDYLKGYSPLHSVRAGVSYPST 613
Query: 552 LIYTGLHDDRVHPAHALKFFMKLKEVNA---PVYLRVETKSGHMGASPETRARELT-DLL 607
L+ T HDDRV PAH+ KF L+ +A P +R+ET +GH +P + E + D+
Sbjct: 614 LVTTADHDDRVVPAHSFKFAATLQADDAGPHPQLIRIETNAGHGAGTPVAKLIEQSADIY 673
Query: 608 AFVLLHL 614
AF L +
Sbjct: 674 AFTLFEM 680
>sp|Q06903|PPCE_AERHY PROLYL ENDOPEPTIDASE (POST-PROLINE CLEAVING ENZYME) (PE)
>gi|216201|dbj|BAA03105.1| (D14005) prolyl endopeptidase
[Aeromonas hydrophila]
Length = 690
Score = 246 bits (622), Expect = 5e-64
Identities = 192/667 (28%), Positives = 322/667 (47%), Gaps = 68/667 (10%)
Query: 3 DPYIWMENLQDERVLKIVEEENRRFRELVGELSDK-----LFPEVWEYFSQPSIGMARIT 57
DPY W+E+ + V+ +NR ++ + ++ + W Y + +
Sbjct: 28 DPYRWLEDDRSPETEAWVKAQNRVTQDYLAQIPFRDAIKGKLATSWNYAKEGAPFREGRY 87
Query: 58 KRGIIVSYSEKDRVTVRWLGG---EVIVDSKELEKELNDEVLLQGFTTDEDGKRLAYSFS 114
+ V L G EV +D L + L + DGK LAYS S
Sbjct: 88 HYFFKNDGLQNQNVLCGQLAGKPAEVFLDPNLLSPD--GTTALDQLSFSRDGKTLAYSLS 145
Query: 115 IGGSDEGITRIIDLETGELLE----EIKPSVWNIVFL-DKGYYFARFYRKEKTPDGVNPP 169
+ GSD ++D+E+ + LE ++K S I +L ++G++++ + + + +
Sbjct: 146 LAGSDWREIHLMDVESKQPLETPLRDVKFS--GISWLGNEGFFYSSYDKPDGSELSARTD 203
Query: 170 AERIFWKD----EEGERMVFGEGLTSGY-FMSLRKSTDGKFAMLTLTYGWNKAEIYLGPI 224
++++ +E +R+VFG + ++ + D ++ +++ + +Y+ +
Sbjct: 204 QHKLYFHRLGTAQEEDRLVFGAIPAQRHRYVGATVTEDDRYLLISAADSTSGNRLYVKDL 263
Query: 225 DKPEEWKKVYSADVPAEPIDVIDGK---LYILTKEGKGLGKVIAVKDSEVEEIIPEGEFP 281
+ D+ A+ + ++D K LY+LT +++ V+ + P
Sbjct: 264 TREGAPLLTVQGDLAAD-VSLVDNKGSRLYLLTNRDAPNRRLVTVE--------ADNPGP 314
Query: 282 LEWAVIVKDK------------ILAGRLVHASHKLEVYNLKGEKISEVEFDFPGSLYPLD 329
+W ++ ++ + A +V A+ ++E ++ G+++ EV GS+ +
Sbjct: 315 EQWRDLIPERQQVLTVHSGGGYLFAEYMVDATARVEQFDHDGKRVREVGLPGLGSVSGFN 374
Query: 330 --KDDERALLRYTSFTVPYRIYEFKDELKIVEERKVEG------NFKVEEDFAISKDGTR 381
+DD + ++ P +Y+F+ + + ++ E+ F SKDGTR
Sbjct: 375 GKQDDPALYFGFENYAQPPTLYKFEPNSGAISLYRASAAPFKPEDYVSEQRFYRSKDGTR 434
Query: 382 VHYFIV--KGEK--DEKKAWVFGYGGFNISLTPRFFPQVIPFLKRGGIFVMANLRGGSEY 437
V I KG K ++GYGGF++SLTP F V +L GG++ +ANLRGG EY
Sbjct: 435 VPLIISYRKGLKLDGSNPTILYGYGGFDVSLTPSFSVSVANWLDLGGVYAVANLRGGGEY 494
Query: 438 GEEWHRAGMRENKQNVFDDFIAVLEKLKKEGY----KVAAWGRSNGGLLVSATLVQRPDV 493
G+ WH AG R NKQNVFDDFIA E LK EGY ++A G SNGGLLV A + QRPD+
Sbjct: 495 GQAWHLAGTRMNKQNVFDDFIAAAEYLKAEGYTRTDRLAIRGGSNGGLLVGAVMTQRPDL 554
Query: 494 MDVALIGYPVIDMLRFHKLYIGSVWIPEYGNPDDPKDR-EFLLKYSPYHNVRP-QEYPPT 551
M VA V+DMLR+H G+ W +YG D + ++L YSP H+VR YP T
Sbjct: 555 MRVACQAVGVLDMLRYHTFTAGAGWAYDYGTSADSEAMFDYLKGYSPLHSVRAGVSYPST 614
Query: 552 LIYTGLHDDRVHPAHALKFFMKLKEVNA---PVYLRVETKSGHMGASPETRARELT-DLL 607
L+ T HDDRV PAH+ KF L+ +A P +R+ET +GH +P + E + D+
Sbjct: 615 LVTTADHDDRVVPAHSFKFAATLQADDAGPHPQLIRIETNAGHGAGTPVAKLIEQSADIY 674
Query: 608 AFVLLHL 614
AF L +
Sbjct: 675 AFTLFEM 681
>dbj|BAA86936.1| (AB020018) prolyl endopeptidase [Homo sapiens]
Length = 710
Score = 246 bits (621), Expect = 6e-64
Identities = 207/688 (30%), Positives = 327/688 (47%), Gaps = 93/688 (13%)
Query: 3 DPYIWMENLQDERVLKIVEEENR-------------RFRELVGELSDKL-----FPEVWE 44
DPY W+E+ E+ VE +N+ ++E + EL D F +
Sbjct: 26 DPYAWLEDPDSEQTKAFVEAQNKITVPFLEQCPIRGLYKERMTELYDYPKYSCHFKKGKR 85
Query: 45 YFSQPSIGMARITKRGIIVSYSEKDRVTVRWLGGEVIVDSKELEKELNDEVLLQGFTTDE 104
YF + G+ +R + V S + V +L ++ D + V L+G+ E
Sbjct: 86 YFYFYNTGLQN--QRVLYVQDSLEGEARV-FLDPNILSD--------DGTVALRGYAFSE 134
Query: 105 DGKRLAYSFSIGGSDEGITRIIDL----ETGELLEEIKPSVWNIVFLDKGYYFARFYRKE 160
DG+ AY S GSD + + + E ++LE +K S KG ++ + +++
Sbjct: 135 DGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFSCMAWTHDGKGMFYNSYPQQD 194
Query: 161 KTPDGVNPPA---ERIFWK---DEEGERMVFGEGLTSGYFMS-LRKSTDGKFAMLTLTYG 213
DG +++++ ++ E ++ E +M S DG++ +L++ G
Sbjct: 195 GKSDGTETSTNLHQKLYYHVLGTDQSEDILCAEFPDEPKWMGGAELSDDGRYVLLSIREG 254
Query: 214 WNKAEIYLGPIDKPEEWKKVYSADVPAEPIDVIDGKLYILTKEGKGLG----------KV 263
+ L D +E + + ID +G+ +T EG +V
Sbjct: 255 CDPVN-RLWYCDLQQESSGIAGILKWVKLIDNFEGEYDYVTNEGAVFTFKTNRQSPNYRV 313
Query: 264 IAVKDSEVEE-----IIPEGEFP-LEWAVIVKDKILAGRLVH-ASHKLEVYNLK-GEKIS 315
I + + EE ++PE E LEW V+ L +H + L++++L G +
Sbjct: 314 INIDFRDPEESKWKVLVPEHEKDVLEWIACVRSNFLVLCYLHDVKNILQLHDLTTGALLK 373
Query: 316 EVEFDFPGSL--YPLDKDDERALLRYTSFTVPYRIYEF---KDEL--KIVEERKVEG--- 365
D GS+ Y K D ++TSF P IY K+EL ++ E V+G
Sbjct: 374 TFPLDV-GSIVGYSGQKKDTEIFYQFTSFLSPGIIYHCDLTKEELEPRVFREVTVKGIDA 432
Query: 366 -NFKVEEDFAISKDGTRVHYFIVKGEK----DEKKAWVFGYGGFNISLTPRFFPQVIPFL 420
+++ + F SKDGT++ FIV + A+++GYGGFNIS+TP + + F+
Sbjct: 433 SDYQTVQIFYPSKDGTKIPMFIVHKKSIKLDGSHPAFLYGYGGFNISITPNYSVSRLIFV 492
Query: 421 KR-GGIFVMANLRGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGY----KVAAWG 475
+ GGI +AN+RGG EYGE WH+ G+ NKQN FDDF E L KEGY ++ G
Sbjct: 493 RHMGGILAVANIRGGGEYGETWHKGGILANKQNCFDDFQCAAEYLIKEGYTSPKRLTING 552
Query: 476 RSNGGLLVSATLVQRPDVMDVALIGYPVIDMLRFHKLYIGSVWIPEYGNPDDPKDREFLL 535
SNGGLLV+A QRPD+ + V+DML+FHK IG W +YG D + E+L+
Sbjct: 553 GSNGGLLVAACANQRPDLFGCVIAQVGVMDMLKFHKYTIGHAWTTDYGCSDSKQHFEWLV 612
Query: 536 KYSPYHNVRPQE-----YPPTLIYTGLHDDRVHPAHALKFFMKLKEV-------NAPVYL 583
KYSP HNV+ E YP L+ T HDDRV P H+LKF L+ + + P+ +
Sbjct: 613 KYSPLHNVKLPEADDIQYPSMLLLTADHDDRVVPLHSLKFIATLQYIVGRSRKQSNPLLI 672
Query: 584 RVETKSGHMGASPETRA-RELTDLLAFV 610
V+TK+GH P + E++D+ AF+
Sbjct: 673 HVDTKAGHGAGKPTAKVIEEVSDMFAFI 700
>pir||JC2257 prolyl oligopeptidase (EC 3.4.21.26) - human
>gi|904214|dbj|BAA04661.1| (D21102) prolyl endopeptidase
[Homo sapiens]
Length = 710
Score = 243 bits (615), Expect = 3e-63
Identities = 207/688 (30%), Positives = 326/688 (47%), Gaps = 93/688 (13%)
Query: 3 DPYIWMENLQDERVLKIVEEENR-------------RFRELVGELSDKL-----FPEVWE 44
DPY W+E+ E+ VE +N+ ++E + EL D F +
Sbjct: 26 DPYAWLEDPDSEQTKAFVEAQNKITVPFLEQCPIRGLYKERMTELYDYPKYSCHFKKGKR 85
Query: 45 YFSQPSIGMARITKRGIIVSYSEKDRVTVRWLGGEVIVDSKELEKELNDEVLLQGFTTDE 104
YF + G+ +R + V S + V +L ++ D + V L+G+ E
Sbjct: 86 YFYFYNTGLQN--QRVLYVQDSLEGEARV-FLDPNILSD--------DGTVALRGYAFSE 134
Query: 105 DGKRLAYSFSIGGSDEGITRIIDL----ETGELLEEIKPSVWNIVFLDKGYYFARFYRKE 160
DG+ AY S GSD + + + E ++LE +K S KG ++ + +++
Sbjct: 135 DGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFSCMAWTHDGKGMFYNSYPQQD 194
Query: 161 KTPDGVNPPA---ERIFWK---DEEGERMVFGEGLTSGYFMS-LRKSTDGKFAMLTLTYG 213
DG +++++ ++ E ++ E +M S DG + +L++ G
Sbjct: 195 GKSDGTETSTNLHQKLYYHVLGTDQSEDILCAEFPDEPKWMGGAELSDDGCYVLLSIREG 254
Query: 214 WNKAEIYLGPIDKPEEWKKVYSADVPAEPIDVIDGKLYILTKEGKGLG----------KV 263
+ L D +E + + ID +G+ +T EG +V
Sbjct: 255 CDPVN-RLWYCDLQQESSGIAGILKWVKLIDNFEGEYDYVTNEGAVFTFKTNRQSPNYRV 313
Query: 264 IAVKDSEVEE-----IIPEGEFP-LEWAVIVKDKILAGRLVH-ASHKLEVYNLK-GEKIS 315
I + + EE ++PE E LEW V+ L +H + L++++L G +
Sbjct: 314 INIDFRDPEESKWKVLVPEHEKDVLEWIACVRSNFLVLCYLHDVKNILQLHDLTTGALLK 373
Query: 316 EVEFDFPGSL--YPLDKDDERALLRYTSFTVPYRIYEF---KDEL--KIVEERKVEG--- 365
D GS+ Y K D ++TSF P IY K+EL ++ E V+G
Sbjct: 374 TFPLDV-GSIVGYSGQKKDTEIFYQFTSFLSPGIIYHCDLTKEELEPRVFREVTVKGIDA 432
Query: 366 -NFKVEEDFAISKDGTRVHYFIVKGEK----DEKKAWVFGYGGFNISLTPRFFPQVIPFL 420
+++ + F SKDGT++ FIV + A+++GYGGFNIS+TP + + F+
Sbjct: 433 SDYQTVQLFYPSKDGTKIPMFIVHKKSIKLDGSHPAFLYGYGGFNISITPNYSVSRLIFV 492
Query: 421 KR-GGIFVMANLRGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGY----KVAAWG 475
+ GGI +AN+RGG EYGE WH+ G+ NKQN FDDF E L KEGY ++ G
Sbjct: 493 RHMGGILAVANIRGGGEYGETWHKGGILANKQNCFDDFQCAAEYLIKEGYTSPKRLTING 552
Query: 476 RSNGGLLVSATLVQRPDVMDVALIGYPVIDMLRFHKLYIGSVWIPEYGNPDDPKDREFLL 535
SNGGLLV+A QRPD+ + V+DML+FHK IG W +YG D + E+L+
Sbjct: 553 GSNGGLLVAACANQRPDLFGCVIAQVGVMDMLKFHKYTIGHAWTTDYGCSDSKQHFEWLV 612
Query: 536 KYSPYHNVRPQE-----YPPTLIYTGLHDDRVHPAHALKFFMKLKEV-------NAPVYL 583
KYSP HNV+ E YP L+ T HDDRV P H+LKF L+ + + P+ +
Sbjct: 613 KYSPLHNVKLPEADDIQYPSMLLLTADHDDRVVPLHSLKFIATLQYIVGRSRKQSNPLLI 672
Query: 584 RVETKSGHMGASPETRA-RELTDLLAFV 610
V+TK+GH P + E++D+ AF+
Sbjct: 673 HVDTKAGHGAGKPTAKVIEEVSDMFAFI 700
>pir||JC5877 prolyl oligopeptidase (EC 3.4.21.26) - bovine
>gi|5103285|dbj|BAA78907.1| (AB028866) prolyl
oligopeptidase [Bos taurus]
Length = 710
Score = 241 bits (609), Expect = 2e-62
Identities = 209/692 (30%), Positives = 330/692 (47%), Gaps = 101/692 (14%)
Query: 3 DPYIWMENLQDERVLKIVEEENR-------------RFRELVGELSDKL-----FPEVWE 44
DPY W+E+ E+ VE +N+ ++E + EL D F +
Sbjct: 26 DPYAWLEDPDSEQTKAFVEAQNKITVPFLEQCPIRGLYKERMTELYDYPKYSCNFKKGKR 85
Query: 45 YFSQPSIGMARITKRGIIVSYSEKDRVTVRWLGGE--VIVDSKELEKELNDEVLLQGFTT 102
YF + G+ +R + V S L GE V +D L + V L+G+
Sbjct: 86 YFYFYNTGLQN--QRVLYVQDS---------LEGEARVCLDPNTLSDD--GTVALRGYAF 132
Query: 103 DEDGKRLAYSFSIGGSDEGITRIIDL----ETGELLEEIKPSVWNIVFLDKGYYFARFYR 158
EDG+ +AY S GSD + + + E ++LE +K S KG ++ + +
Sbjct: 133 SEDGEYVAYGLSASGSDWVTIKFMKVDGAKELADVLERVKFSCMAWTHDGKGMFYNAYPQ 192
Query: 159 KEKTPDGVNPPA---ERIFWK---DEEGERMVFGEGLTSGYFMS-LRKSTDGKFAMLTLT 211
++ DG +++ + ++ E ++ E +M S DG++ +L++
Sbjct: 193 QDGKSDGTETSTNLHQKLCYHVLGTDQSEDILCAEFPDEPKWMGGAELSDDGRYVLLSIR 252
Query: 212 YGWNKAEIYLGPIDKPEEWKKVYSADVPAEPIDVIDGKLYILTKEGKGLG---------- 261
G + L D +E + + ID +G+ +T EG
Sbjct: 253 EGCDPVN-RLWYCDLHQEPNGITGILKWVKLIDNFEGEYDYVTNEGTVFTFKTNRHSPNY 311
Query: 262 KVIAVKDSEVEE-----IIPEGEFP-LEWAVIVKDKILAGRLVH-ASHKLEVYNLKGEKI 314
++I + ++ EE ++PE E LEW V+ L +H + L+++++ +
Sbjct: 312 RLINIDFTDPEESRWKVLVPEHEKDVLEWVACVRSNFLVLCYLHDVKNTLQLHDMATGAL 371
Query: 315 SEVEFDFP---GSL--YPLDKDDERALLRYTSFTVPYRIYEF---KDEL--KIVEERKVE 364
+ FP GS+ Y K D ++TSF P IY K+EL ++ E V+
Sbjct: 372 LKT---FPLEVGSVVGYSGQKKDTEIFYQFTSFLSPGIIYHCDLTKEELEPRVFREVTVK 428
Query: 365 G----NFKVEEDFAISKDGTRVHYFIV--KGEK--DEKKAWVFGYGGFNISLTPRFFPQV 416
G +++ + F SKDGT++ FIV KG K A+++GYGGFNIS+TP +
Sbjct: 429 GIDASDYQTVQIFYPSKDGTKIPMFIVHKKGIKLDGSHPAFLYGYGGFNISITPNYSVCR 488
Query: 417 IPFLKR-GGIFVMANLRGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGY----KV 471
+ F++ GG+ +AN+RGG EYGE WH+ G+ NKQN FDDF E L KEGY ++
Sbjct: 489 LIFVRHMGGVLAVANIRGGGEYGETWHKGGILANKQNCFDDFQCAAEYLIKEGYTSPKRL 548
Query: 472 AAWGRSNGGLLVSATLVQRPDVMDVALIGYPVIDMLRFHKLYIGSVWIPEYGNPDDPKDR 531
G SNGGLLV+ QRPD+ + V+DML+FHK IG W +YG D+ +
Sbjct: 549 TINGGSNGGLLVATCANQRPDLFGCVIAQVGVMDMLKFHKYTIGHAWTTDYGCSDNKQHF 608
Query: 532 EFLLKYSPYHNVRPQE-----YPPTLIYTGLHDDRVHPAHALKFFMKLKEV-------NA 579
E+L+KYSP HNV+ E YP L+ T HDDRV P H+ KF L+ + N
Sbjct: 609 EWLIKYSPLHNVKLPEADDIQYPSMLLLTADHDDRVVPLHSPKFIATLQHLVGRSRKQNN 668
Query: 580 PVYLRVETKSGHMGASPETRA-RELTDLLAFV 610
P+ + V+TK+GH P + E++D+ AF+
Sbjct: 669 PLLIHVDTKAGHGAGKPTAKVIEEVSDMFAFI 700
>gi|6755152 prolyl endopeptidase [Mus musculus] >gi|7435601|pir||JW0080 prolyl
endopeptidase (EC 3.4.-.-) - mouse
>gi|5689035|dbj|BAA83071.1| (AB022053) prolyl
oligopeptidase [Mus musculus]
>gi|6561876|dbj|BAA88239.1| (AB007631) Prolyl
endopeptidase [Mus musculus]
Length = 710
Score = 241 bits (609), Expect = 2e-62
Identities = 210/690 (30%), Positives = 329/690 (47%), Gaps = 97/690 (14%)
Query: 3 DPYIWMENLQDERVLKIVEEENR-------------RFRELVGELSDKL-----FPEVWE 44
DPY W+E+ E+ VE +N+ ++E + EL D F +
Sbjct: 26 DPYSWLEDPDSEQTKAFVEAQNKITVPFLEQCPIRGLYKERMTELYDYPKYSCHFKKGKR 85
Query: 45 YFSQPSIGMARITKRGIIVSYSEKDRVTVRWLGGE--VIVDSKELEKELNDEVLLQGFTT 102
YF + G+ +R + V S L GE V +D L + V L+G+
Sbjct: 86 YFYFYNTGLQN--QRVLYVQDS---------LEGEARVFLDPNTLSDD--GTVALRGYAF 132
Query: 103 DEDGKRLAYSFSIGGSDEGITRIIDL----ETGELLEEIKPSVWNIVFLDKGYYFARFYR 158
EDG+ AY S GSD + + + E ++LE +K + KG ++ + +
Sbjct: 133 SEDGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFTCMAWTHDGKGMFYNSYPQ 192
Query: 159 KEKTPDGVNPPA---ERIFWK---DEEGERMVFGEGLTSGYFMS-LRKSTDGKFAMLTLT 211
++ DG +++ + ++ E ++ E +M S DG++ +L++
Sbjct: 193 QDGKSDGTETSTNLHQKLCYHVLGTDQSEDILCAEFPDEPKWMGGAELSDDGRYVLLSIW 252
Query: 212 YGWNKAEIYLGPIDKPEEWKKVYSADVPAEPIDVIDGKLYILTKEGKGLG---------- 261
G + L D +E + + ID +G+ +T EG
Sbjct: 253 EGCDPVN-RLWYCDLQQEPNGITGILKWVKLIDNFEGEYDYVTNEGTVFTFKTNRNSPNY 311
Query: 262 KVIAVKDSEVEE-----IIPEGEFP-LEWAVIVKDKILAGRLVH-ASHKLEVYNLK-GEK 313
++I + ++ +E ++PE E LEW V+ L +H + L++++L G
Sbjct: 312 RLINIDFTDPDESKWKVLVPEHEKDVLEWVACVRSNFLVLCYLHDVKNILQLHDLTTGAL 371
Query: 314 ISEVEFDFPGSL--YPLDKDDERALLRYTSFTVPYRIYEF---KDELK--IVEERKVEG- 365
+ D GS+ Y K D ++TSF P IY K+EL+ + E V+G
Sbjct: 372 LKTFPLDV-GSVVGYSGRKKDSEIFYQFTSFLSPGVIYHCDLTKEELEPMVFREVTVKGI 430
Query: 366 ---NFKVEEDFAISKDGTRVHYFIV--KGEK--DEKKAWVFGYGGFNISLTPRFFPQVIP 418
+++ + F SKDGT++ FIV KG K A+++GYGGFNIS+TP + +
Sbjct: 431 DAADYQTIQIFYPSKDGTKIPMFIVHKKGIKLDGSHPAFLYGYGGFNISITPNYSVSRLI 490
Query: 419 FLKR-GGIFVMANLRGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGY----KVAA 473
F++ GG+ +AN+RGG EYGE WH+ G+ NKQN FDDF E L KEGY ++
Sbjct: 491 FVRHMGGVLAVANIRGGGEYGETWHKGGILANKQNCFDDFQCAAEYLIKEGYTSPKRLTI 550
Query: 474 WGRSNGGLLVSATLVQRPDVMDVALIGYPVIDMLRFHKLYIGSVWIPEYGNPDDPKDREF 533
G SNGGLLV+A QRPD+ + V+DML+FHK IG W +YG D + E+
Sbjct: 551 NGGSNGGLLVAACANQRPDLFGCVIAQVGVMDMLKFHKFTIGHAWTTDYGCSDTKQHFEW 610
Query: 534 LLKYSPYHNVRPQE-----YPPTLIYTGLHDDRVHPAHALKFFMKLKEV-------NAPV 581
LLKYSP HNV+ E YP L+ T HDDRV P H+LKF L+ + + P+
Sbjct: 611 LLKYSPLHNVKLPEADDIQYPSMLLLTADHDDRVVPLHSLKFIATLQYIVGRSRKQSNPL 670
Query: 582 YLRVETKSGHMGASPETRA-RELTDLLAFV 610
+ V+TK+GH P + E++D+ AF+
Sbjct: 671 LIHVDTKAGHGAGKPTAKVIEEVSDMFAFI 700
>gb|AAF52942.1| (AE003628) CG5355 gene product [Drosophila melanogaster]
Length = 717
Score = 241 bits (608), Expect = 2e-62
Identities = 210/687 (30%), Positives = 321/687 (46%), Gaps = 86/687 (12%)
Query: 1 MEDPYIWMENLQDERVLKIVEEENRRFRELV--GELSDKLFPEVWEYFSQPSIGMAR--- 55
++D Y W+E+ + V +N R + GE KL ++ + ++ P G
Sbjct: 29 IKDVYRWLEDPDSTETEEFVNAQNSISRPFLENGEEWKKLNTKLTKLWNYPKYGCPMRYG 88
Query: 56 -----ITKRGI---IVSYSEKDRVTVRWLGGE----VIVDSKELEKELNDEVLLQGFTTD 103
G+ V Y +K LG E V +D L ++ + + F+
Sbjct: 89 NYYYYFMNTGLQNQSVMYQQKS------LGDESESKVFLDPNTLSEDGTIALTQKAFS-- 140
Query: 104 EDGKRLAYSFSIGGSDEGITRIIDLETG----ELLEEIKPSVWNIVFLDKGYYFARFYRK 159
EDGK +AY S GSD I D ETG E+LE++K S + +KG+++ R+ +
Sbjct: 141 EDGKYMAYGLSESGSDWIKILIRDAETGKDLSEVLEKVKFSEISWTKDNKGFFYGRYPDQ 200
Query: 160 EKTPDGVNPPA---ERIFW----KDEEGERMVFGEGLTSGYFMSLRKSTDGKFAMLTLTY 212
+ DG +++++ + ++ + +V + + S GK+ +L +
Sbjct: 201 DGKTDGSETKQNENQKLYYHRVGESQDKDTLVVEFPEEPSWRIQSTVSDCGKYLILAIVK 260
Query: 213 GWNKAEIYLGPIDKPEEW-------KKVYSADVPAEPIDVIDGKLYILTKEGKGLGKVIA 265
++ + E K V + + I K++ T + +VIA
Sbjct: 261 DCRDNIVFYADLTPGAEITSKLNVKKIVEKFEADYDYITNEGSKIFFRTNKNAPNYQVIA 320
Query: 266 VK-----DSEVEEIIPEGEFP-LEWAVIV-KDKILAGRLVHASHKLEVYNLK-GEKISEV 317
+ + + E +I E + L+W V DK+L + L+V +LK G + E
Sbjct: 321 IDFNNSAEDKWETLIAEHKSDVLDWVKCVDNDKLLVCYIRDVKSVLQVNSLKDGTLLREF 380
Query: 318 EFDFPGSLYPL--DKDDERALLRYTSFTVPYRIY--EFKD---------ELKIVEERKVE 364
+ D G++ +K ++SF P IY +FK E+K+ E
Sbjct: 381 DLDI-GTIVGTSGEKKYSEIFYNFSSFLNPGSIYRYDFKTPDKSPSVFREIKLNLEGFRR 439
Query: 365 GNFKVEEDFAISKDGTRVHYFIVKGEKDE---KKAWVFGYGGFNISLTPRFFPQVIPFLK 421
++ VE+ F SKDGT+V FI++ ++D + ++GYGGFNIS+ P F + F+
Sbjct: 440 EDYAVEQIFYKSKDGTKVPMFIIRKKRDSVEPRPCLLYGYGGFNISMLPSFGLSGLMFID 499
Query: 422 R-GGIFVMANLRGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGY----KVAAWGR 476
G+ NLRGG EYGE+WH G NKQNVFDDF A E L + Y ++A G
Sbjct: 500 TFDGVLAYPNLRGGGEYGEKWHNGGRLLNKQNVFDDFQAAAEYLIENKYTTKDRLAIQGG 559
Query: 477 SNGGLLVSATLVQRPDVMDVALIGYPVIDMLRFHKLYIGSVWIPEYGNPDDPKDREFLLK 536
SNGGLLV + + QRPD+ A+ V+DMLRFHK IG W +YGNP + + + L K
Sbjct: 560 SNGGLLVGSCINQRPDLFGAAVAQVGVMDMLRFHKFTIGHAWCSDYGNPSEKEHFDNLYK 619
Query: 537 YSPYHNVR-----PQEYPPTLIYTGLHDDRVHPAHALKFFMKLKEV-------NAPVYLR 584
+SP HNV EYP TLI T HDDRV P H+LKF L+E PV LR
Sbjct: 620 FSPLHNVHTPKGAETEYPSTLILTADHDDRVSPLHSLKFIAALQEAVRDSEFQKNPVLLR 679
Query: 585 VETKSGHMGASPET-RARELTDLLAFV 610
V K+GH P + R E TD+L F+
Sbjct: 680 VYQKAGHGAGKPTSKRIEEATDILTFL 706
>gb|AAG10464.1|AF279106_26 (AF279106) predicted prolyl endopeptidase [uncultured
proteobacterium EBAC31A08]
Length = 704
Score = 239 bits (603), Expect = 8e-62
Identities = 193/664 (29%), Positives = 313/664 (47%), Gaps = 89/664 (13%)
Query: 1 MEDPYIWMENLQDERVLKIVEEENRRFRELVGELSDKL-----FPEVWEYFSQPSIGMAR 55
+ED Y WME+ E VE +N ++ +G+ K EVW+ SI M
Sbjct: 46 IEDAYRWMEDFTSEDSTDWVERQNNFTQKFIGQNKYKKSIAKNLDEVWD---TDSISMPY 102
Query: 56 ITKRGIIVSYSEKDRVTVRWLGGEVIVDSKELEKELNDEVLLQGFTTDEDG--------- 106
+ +++ W ++++ E E D VLL EDG
Sbjct: 103 QVNKKTFYYFNDGS-----WQQSKLMIKDCE---ECQDRVLLDPNQFSEDGTISLASTSV 154
Query: 107 ----KRLAYSFSIGGSDEGITRIIDLETGELLEE------IKPSVWNIVFLDKGYYFARF 156
LA+S S GGSD +++D+E+G+ L++ + W D G+Y+ ++
Sbjct: 155 SNDASLLAFSISDGGSDWRTWKVLDIESGKTLDDRIEWAKFSGASWEND--DSGFYYQKY 212
Query: 157 YR-KEKTPDGVNPPAERIFWK---DEEGERMVFGEGLTSGYFMSLRKSTDGKFAMLTLTY 212
E+ +N + +F K ++ + +V+ + + D K L++
Sbjct: 213 DEPSEELLKDINTAPKLMFHKIGTAQDEDVIVYENPEKPRWSWGISVVKDSKIKFLSIGE 272
Query: 213 GW---NKAEIYLGPIDKP-----EEWKKVYSADVPAEPIDVIDGKLYILTKEGKGLGKVI 264
G N+ + L P D+P +E YS ++ + + + E GKV+
Sbjct: 273 GTDERNRLYVQLSP-DQPFIPLIDELIGAYSF------LESKNDTFWFYSTENAANGKVV 325
Query: 265 A--VKDSEV--EEIIPEGEFPLEWAVIVKDKILAGRLVHASHKLEVYNLKGEKISEVEFD 320
+ +K+ E++ E + + + I+ LV ++ ++LKG +++ +
Sbjct: 326 SLTIKNGSFVWNEVVGESTNSISSVSFINNSIVVSYLVDTFTEVHFFDLKGAYKNKLATE 385
Query: 321 FPGSL--YPLDKDDERALLRYTSFTVPYRIYE-----------FKDELKIVEERKVEGNF 367
G++ + + +DE + +T+F P IY+ +K++LK + +F
Sbjct: 386 RKGTMGGFGGEIEDEVSYFSFTNFVTPREIYKINLTDMSQELFWKEDLKGHDSTLFTSDF 445
Query: 368 KVEEDFAISKDGTRV--HYFIVKGEKDEKKAWV--FGYGGFNISLTPRFFPQVIPFLKRG 423
K F SKDGT++ H K K + + +GYGGFNIS P F + ++ +G
Sbjct: 446 K----FFPSKDGTQIPIHLSYKKSLKIDSNTPILLYGYGGFNISRLPGFSKSYLTWMNQG 501
Query: 424 GIFVMANLRGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGY----KVAAWGRSNG 479
GI + NLRGG EYG+ WH AG NKQNVFDDF + L + A G SNG
Sbjct: 502 GIVAVVNLRGGGEYGDNWHDAGRLFNKQNVFDDFAYSAKFLHAQEIGSPSSTAIQGGSNG 561
Query: 480 GLLVSATLVQRPDVMDVALIGYPVIDMLRFHKLYIGSVWIPEYGNPDDPKDREFLLKYSP 539
GLLV+AT++Q P++ VA+ V+DMLRFHK IG W +YG+PD + E LL YSP
Sbjct: 562 GLLVAATMLQNPNLFKVAIPQVGVLDMLRFHKFTIGWAWESDYGSPDKKDEFENLLAYSP 621
Query: 540 YHNVRPQE-YPPTLIYTGLHDDRVHPAHALKFFMKLKE---VNAPVYLRVETKSGHMGAS 595
HN+ E YP TLI T DDRV P+H+ KF KL+E + P+ +R+E ++GH +
Sbjct: 622 LHNIVEGECYPTTLITTAKRDDRVVPSHSFKFAAKLQESQGCDNPILIRIEGRAGHGAGT 681
Query: 596 PETR 599
P+ +
Sbjct: 682 PKNK 685
>sp|P27028|PPCE_FLAME PROLYL ENDOPEPTIDASE PRECURSOR (POST-PROLINE CLEAVING ENZYME) (PE)
(VERSION 1) >gi|77550|pir||JX0194 prolyl oligopeptidase
(EC 3.4.21.26) - Flavobacterium meningosepticum
>gi|216707|dbj|BAA01755.1| (D10980) prolyl endopeptidase
[Chryseobacterium meningosepticum]
>gi|456523|emb|CAA45213.1| (X63674) prolyl endopeptidase
[Chryseobacterium meningosepticum]
Length = 705
Score = 239 bits (603), Expect = 8e-62
Identities = 188/671 (28%), Positives = 329/671 (49%), Gaps = 73/671 (10%)
Query: 1 MEDPYIWMENLQDERVLKIVEEENRRFRELVGELS-----DKLFPEVWEYFSQPSIGMAR 55
+ DPY W+E+ + E V++E + ++ + ++ K ++W Y ++
Sbjct: 45 VSDPYRWLEDDRAEDTKAWVQQEVKFTQDYLAQIPFRDQLKKQLMDIWNYEK-----ISA 99
Query: 56 ITKRGIIVSYSEKDRVTVRWL--------GGEVIVDSKELEKELNDEVLLQGFTTDEDGK 107
K+G +S+ D + + + EV +D + ++ + F ++ G
Sbjct: 100 PFKKGKYTYFSKNDGLQAQSVLYRKDAAGKTEVFLDPNKFSEKGTTSLASVSF--NKKGT 157
Query: 108 RLAYSFSIGGSDEGITRIIDLETGELLEEIKPSVW--NIVFL-DKGYYFARFYRKEKTP- 163
+AYS S GGSD I+D ET + L+E V I +L D+G++++ + + ++
Sbjct: 158 LVAYSISEGGSDWNKIIILDAETKKQLDETLLDVKFSGISWLGDEGFFYSSYDKPKEGSV 217
Query: 164 -DGVNPPAERIFWK---DEEGERMVFGEGLTSGYFMSLRKSTDGKFAMLTLTYGWNKAEI 219
G+ + F K + + ++ G ++ + D ++ +++ N E+
Sbjct: 218 LSGMTDKHKVYFHKLGTKQSQDELIIGGDKFPRRYIGAYVTDDQRYLVVSAANATNGNEL 277
Query: 220 YLGPIDKPEEWKKVYSA-DVPAEPIDVIDGKLYILTKEGKGLGKVIAV-----KDSEVEE 273
Y+ + ++ + + D D LY+ T + +++ K ++
Sbjct: 278 YIKDLKNKTDFIPIITGFDSNVNVADTDGDTLYLFTDKDAPNKRLVKTTIQNPKAETWKD 337
Query: 274 IIPEGEFPLE--------WAVIVKDKILAGRLVHASHKLEVYNLKGEKISEVEFDFPGSL 325
+I E PLE +A +KD I +++ Y+ G+ + ++ G+
Sbjct: 338 VIAETSEPLEINTGGGYFFATYMKDAI---------DQVKQYDKNGKLVRAIKLPGSGNA 388
Query: 326 --YPLDKDDERALLRYTSFTVPYRIYEFK---DELKIVEERKVE---GNFKVEEDFAISK 377
+ +K ++ +T++ P I+++ ++ ++ KV+ N+ E+ F S
Sbjct: 389 SGFGGEKTEKDLYYSFTNYITPPTIFKYNVTTGNSEVYQKPKVKFNPENYVSEQVFYTSS 448
Query: 378 DGTRVHYFIV--KGEKDEKK--AWVFGYGGFNISLTPRFFPQVIPFLKRGGIFVMANLRG 433
DGT++ I KG K + K ++ YGGFNISL P F +++ GGI+ + N+RG
Sbjct: 449 DGTKIPMMISYKKGLKKDGKNPTILYSYGGFNISLQPAFSVVNAIWMENGGIYAVPNIRG 508
Query: 434 GSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGYK----VAAWGRSNGGLLVSATLVQ 489
G EYG++WH AG + K+NVF+DFIA E L+K GY +A GRSNGGLLV AT+
Sbjct: 509 GGEYGKKWHDAGTKMQKKNVFNDFIAAGEYLQKNGYTSKEYMALSGRSNGGLLVGATMTM 568
Query: 490 RPDVMDVALIGYPVIDMLRFHKLYIGSVWIPEYGNPDDPKDR-EFLLKYSPYHNVRPQE- 547
RPD+ VA G V+DMLR++K G+ W +YG +D K+ E+L YSP HNV+
Sbjct: 569 RPDLAKVAFPGVGVLDMLRYNKFTAGAGWAYDYGTAEDSKEMFEYLKSYSPVHNVKAGTC 628
Query: 548 YPPTLIYTGLHDDRVHPAHALKFFMKLKEVNA---PVYLRVETKSGH-MGASPETRAREL 603
YP T++ T HDDRV PAH+ KF +L+ + P+ +R+ET +GH G S E E
Sbjct: 629 YPSTMVITSDHDDRVVPAHSFKFGSELQAKQSCKNPILIRIETNAGHGAGRSTEQVVAEN 688
Query: 604 TDLLAFVLLHL 614
DLL+F L +
Sbjct: 689 ADLLSFALYEM 699
>dbj|BAA25544.1| (AB012759) rPOP [Rattus norvegicus]
Length = 710
Score = 237 bits (598), Expect = 3e-61
Identities = 208/690 (30%), Positives = 328/690 (47%), Gaps = 97/690 (14%)
Query: 3 DPYIWMENLQDERVLKIVEEENR-------------RFRELVGELSDKL-----FPEVWE 44
DPY W+E+ E+ VE +N+ ++E + EL D F +
Sbjct: 26 DPYAWLEDPDSEQTKAFVEAQNKITVPFLEQCPIRGLYKERMTELYDYPKYSCHFKKGKR 85
Query: 45 YFSQPSIGMARITKRGIIVSYSEKDRVTVRWLGGE--VIVDSKELEKELNDEVLLQGFTT 102
YF + G+ +R + V S L GE V +D L + V L+G+
Sbjct: 86 YFYFYNTGLQN--QRVLYVQDS---------LEGEARVFLDPNTLSDD--GTVALRGYAF 132
Query: 103 DEDGKRLAYSFSIGGSDEGITRIIDL----ETGELLEEIKPSVWNIVFLDKGYYFARFYR 158
EDG+ AY S GSD + + + E ++LE +K + KG ++ + +
Sbjct: 133 SEDGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFTCMAWTHDGKGMFYNSYPQ 192
Query: 159 KEKTPDGVNPPA---ERIFWK---DEEGERMVFGEGLTSGYFM-SLRKSTDGKFAMLTLT 211
++ DG +++ + ++ E ++ E +M S DG++ +L++
Sbjct: 193 QDGKSDGTETSTNLHQKLCYHVLGTDQSEDVLCAEFPDEPKWMGGAELSDDGRYVLLSIW 252
Query: 212 YGWNKAEIYLGPIDKPEEWKKVYSADVPAEPIDVIDGKLYILTKEGKGLG---------- 261
G + L D + + + ID +G+ +T EG
Sbjct: 253 EGCDPVN-RLWYCDLQQGSNGINGILKWVKLIDNFEGEYDYITNEGTVFTFKTNRNSPNY 311
Query: 262 KVIAVKDSEVEE-----IIPEGEFP-LEWAVIVKDKILA-GRLVHASHKLEVYNL-KGEK 313
++I + ++ +E ++PE E LEW V+ L L + + L++++L G
Sbjct: 312 RLINIDFTDPDESKWKVLVPEHEKDVLEWVACVRSNFLVLCYLRNVKNILQLHDLTTGAL 371
Query: 314 ISEVEFDFPGSL--YPLDKDDERALLRYTSFTVPYRIYE---FKDEL--KIVEERKVEG- 365
+ D GS+ Y K D ++TSF P IY ++EL ++ E V+G
Sbjct: 372 LKTFPLDV-GSVVGYSGRKKDSEIFYQFTSFLSPGVIYHCDLTREELEPRVFREVTVKGI 430
Query: 366 ---NFKVEEDFAISKDGTRVHYFIV--KGEK--DEKKAWVFGYGGFNISLTPRFFPQVIP 418
+++ + F SKDGT++ FIV KG K A+++GYGGFNIS+TP + +
Sbjct: 431 DASDYQTIQVFYPSKDGTKIPMFIVHKKGIKLDGSHPAFLYGYGGFNISITPNYSVSRLI 490
Query: 419 FLKR-GGIFVMANLRGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGY----KVAA 473
F++ GG+ +AN+RGG EYGE WH+ G+ NKQN FDDF E L KEGY ++
Sbjct: 491 FVRHMGGVLAVANIRGGGEYGETWHKGGILANKQNCFDDFQCAAEYLIKEGYTTSKRLTI 550
Query: 474 WGRSNGGLLVSATLVQRPDVMDVALIGYPVIDMLRFHKLYIGSVWIPEYGNPDDPKDREF 533
G SNGGLLV+A QRPD+ + V+DML+FHK IG W +YG D + E+
Sbjct: 551 NGGSNGGLLVAACANQRPDLFGCVIAQVGVMDMLKFHKFTIGHAWTTDYGCSDSKQHFEW 610
Query: 534 LLKYSPYHNVRPQE-----YPPTLIYTGLHDDRVHPAHALKFFMKLKEV-------NAPV 581
LLKYSP HNV+ E YP L+ T HDDRV P H+LKF L+ + + P+
Sbjct: 611 LLKYSPLHNVKLPEADDIQYPSMLLLTADHDDRVVPLHSLKFIATLQYIVGRSRKQSNPL 670
Query: 582 YLRVETKSGHMGASPETRA-RELTDLLAFV 610
+ V+TK+GH P + E++D+ AF+
Sbjct: 671 LIHVDTKAGHGPGKPTAKVIEEVSDMFAFI 700
>sp|P27195|PPCF_FLAME PROLYL ENDOPEPTIDASE PRECURSOR (POST-PROLINE CLEAVING ENZYME) (PE)
(VERSION 2) >gi|148698|gb|AAA24925.1| (M81461) prolyl
endopeptidase [Chryseobacterium meningosepticum]
Length = 705
Score = 236 bits (596), Expect = 5e-61
Identities = 187/671 (27%), Positives = 330/671 (48%), Gaps = 73/671 (10%)
Query: 1 MEDPYIWMENLQDERVLKIVEEENRRFRELVGELS-----DKLFPEVWEYFSQPSIGMAR 55
+ DPY W+E+ + E V++E + ++ + ++ K ++W Y ++
Sbjct: 45 VSDPYRWLEDDRAEDTKAWVQQEVKFTQDYLAQIPFRGQIKKQLLDIWNYEK-----ISA 99
Query: 56 ITKRGIIVSYSEKDRVTVRWL--------GGEVIVDSKELEKELNDEVLLQGFTTDEDGK 107
K+G + + D + + + EV +D + + L + ++ G
Sbjct: 100 PFKKGKYTYFYKNDGLQAQSVLYRKDASGKTEVFLDPNKFSDK--GTTSLANLSFNKKGT 157
Query: 108 RLAYSFSIGGSDEGITRIIDLETGELLEEIKPSVW--NIVFL-DKGYYFARFYRKE--KT 162
+AYS S GGSD I+D ET + ++E V I +L D+G++++ + + +
Sbjct: 158 LVAYSISEGGSDWNKIIILDAETKKQIDETLLDVKFSGISWLGDEGFFYSSYDKPKDGSV 217
Query: 163 PDGVNPPAERIFWK---DEEGERMVFGEGLTSGYFMSLRKSTDGKFAMLTLTYGWNKAEI 219
G+ + F K + + ++ G ++S + D ++ +++ N E+
Sbjct: 218 LSGMTDKHKVYFHKLGTKQSQDELIIGGDKFPRRYLSGYVTEDQRYLVVSAANATNGNEL 277
Query: 220 YLGPIDKPEEWKKVYSA-DVPAEPIDVIDGKLYILTKEGKGLGKVIAV-----KDSEVEE 273
Y+ + ++ + + + +D L++ T + +++ K ++
Sbjct: 278 YIKDLKNKTDFIPIITGFESNVGLVDTDGDTLFLHTDKNAPNMRMVKTTIQNPKPETWKD 337
Query: 274 IIPEGEFPLE--------WAVIVKDKILAGRLVHASHKLEVYNLKGEKISEVEFDFPGSL 325
+I E P+ +A +KD A +++ Y+ G+ + E++ G+
Sbjct: 338 VIAETSEPMRVNSGGGYFFATYMKD---------ALSQIKQYDKTGKLVREIKLPGSGTA 388
Query: 326 --YPLDKDDERALLRYTSFTVPYRIYEFK---DELKIVEERKVE---GNFKVEEDFAISK 377
+ +K ++ +T++ P I++F + ++ ++ KV+ N+ E+ F S
Sbjct: 389 GGFGGEKTEKELYYSFTNYITPPTIFKFSIDSGKSEVYQKPKVKFNPENYVSEQVFYTSA 448
Query: 378 DGTRVHYFIV--KGEKDEKK--AWVFGYGGFNISLTPRFFPQVIPFLKRGGIFVMANLRG 433
DGT++ I KG K + K ++ YGGFNISL P F +++ GGI+ + N+RG
Sbjct: 449 DGTKIPMMISNKKGLKKDGKNPTILYSYGGFNISLQPAFSVVNAIWMENGGIYAVPNIRG 508
Query: 434 GSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGYK----VAAWGRSNGGLLVSATLVQ 489
G EYG++WH AG ++ K+NVF+DFIA E L+K GY +A GRSNGGLLV AT+
Sbjct: 509 GGEYGKKWHDAGTKQQKKNVFNDFIAAGEYLQKNGYTSKDYMALSGRSNGGLLVGATMTM 568
Query: 490 RPDVMDVALIGYPVIDMLRFHKLYIGSVWIPEYGNPDDPKDR-EFLLKYSPYHNVRPQE- 547
RPD+ VA G V+DMLR++K G+ W +YG +D K+ E+L YSP HNV+
Sbjct: 569 RPDLAKVAFPGVGVLDMLRYNKFTAGAGWAYDYGTAEDSKEMFEYLKSYSPVHNVKAGTC 628
Query: 548 YPPTLIYTGLHDDRVHPAHALKFFMKLKEVNA---PVYLRVETKSGH-MGASPETRAREL 603
YP T++ T HDDRV PAH+ KF +L+ A PV +R+ET +GH G S E E
Sbjct: 629 YPSTMVITSDHDDRVVPAHSFKFGAELQAKQACKNPVLIRIETNAGHGAGRSTEQVVMEN 688
Query: 604 TDLLAFVLLHL 614
DLL+F L +
Sbjct: 689 ADLLSFALYEM 699
>pir||A38086 prolyl oligopeptidase (EC 3.4.21.26) precursor - Flavobacterium
meningosepticum
Length = 705
Score = 236 bits (596), Expect = 5e-61
Identities = 187/671 (27%), Positives = 330/671 (48%), Gaps = 73/671 (10%)
Query: 1 MEDPYIWMENLQDERVLKIVEEENRRFRELVGELS-----DKLFPEVWEYFSQPSIGMAR 55
+ DPY W+E+ + E V++E + ++ + ++ K ++W Y ++
Sbjct: 45 VSDPYRWLEDDRAEDTKAWVQQEVKFTQDYLAQIPFRGQIKKQLLDIWNYEK-----ISA 99
Query: 56 ITKRGIIVSYSEKDRVTVRWL--------GGEVIVDSKELEKELNDEVLLQGFTTDEDGK 107
K+G + + D + + + EV +D + + L + ++ G
Sbjct: 100 PFKKGKYTYFYKNDGLQAQSVLYRKDASGKTEVFLDPNKFSDK--GTTSLANLSFNKKGT 157
Query: 108 RLAYSFSIGGSDEGITRIIDLETGELLEEIKPSVW--NIVFL-DKGYYFARFYRKE--KT 162
+AYS S GGSD I+D ET + ++E V I +L D+G++++ + + +
Sbjct: 158 LVAYSISEGGSDWNKIIILDAETKKQIDETLLDVKFSGISWLGDEGFFYSSYDKPKDGSV 217
Query: 163 PDGVNPPAERIFWK---DEEGERMVFGEGLTSGYFMSLRKSTDGKFAMLTLTYGWNKAEI 219
G+ + F K + + ++ G ++S + D ++ +++ N E+
Sbjct: 218 LSGMTDKHKVYFHKLGTKQSQDELIIGGDKFPRRYLSGYVTEDQRYLVVSAANATNGNEL 277
Query: 220 YLGPIDKPEEWKKVYSA-DVPAEPIDVIDGKLYILTKEGKGLGKVIAV-----KDSEVEE 273
Y+ + ++ + + + +D L++ T + +++ K ++
Sbjct: 278 YIKDLKNKTDFIPIITGFESNVGLVDTDGDTLFLHTDKNAPNMRMVKTTIQNPKPETWKD 337
Query: 274 IIPEGEFPLE--------WAVIVKDKILAGRLVHASHKLEVYNLKGEKISEVEFDFPGSL 325
+I E P+ +A +KD A +++ Y+ G+ + E++ G+
Sbjct: 338 VIAETSEPMRVNSGGGYFFATYMKD---------ALSQIKQYDKTGKLVREIKLPGSGTA 388
Query: 326 --YPLDKDDERALLRYTSFTVPYRIYEFK---DELKIVEERKVE---GNFKVEEDFAISK 377
+ +K ++ +T++ P I++F + ++ ++ KV+ N+ E+ F S
Sbjct: 389 GGFGGEKTEKELYYSFTNYITPPTIFKFSIDSGKSEVYQKPKVKFNPENYVSEQVFYTSA 448
Query: 378 DGTRVHYFIV--KGEKDEKK--AWVFGYGGFNISLTPRFFPQVIPFLKRGGIFVMANLRG 433
DGT++ I KG K + K ++ YGGFNISL P F +++ GGI+ + N+RG
Sbjct: 449 DGTKIPMMISYKKGLKKDGKNPTILYSYGGFNISLQPAFSVVNAIWMENGGIYAVPNIRG 508
Query: 434 GSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGYK----VAAWGRSNGGLLVSATLVQ 489
G EYG++WH AG ++ K+NVF+DFIA E L+K GY +A GRSNGGLLV AT+
Sbjct: 509 GGEYGKKWHDAGTKQQKKNVFNDFIAAGEYLQKNGYTSKDYMALSGRSNGGLLVGATMTM 568
Query: 490 RPDVMDVALIGYPVIDMLRFHKLYIGSVWIPEYGNPDDPKDR-EFLLKYSPYHNVRPQE- 547
RPD+ VA G V+DMLR++K G+ W +YG +D K+ E+L YSP HNV+
Sbjct: 569 RPDLAKVAFPGVGVLDMLRYNKFTAGAGWAYDYGTAEDSKEMFEYLKSYSPVHNVKAGTC 628
Query: 548 YPPTLIYTGLHDDRVHPAHALKFFMKLKEVNA---PVYLRVETKSGH-MGASPETRAREL 603
YP T++ T HDDRV PAH+ KF +L+ A PV +R+ET +GH G S E E
Sbjct: 629 YPSTMVITSDHDDRVVPAHSFKFGAELQAKQACKNPVLIRIETNAGHGAGRSTEQVVMEN 688
Query: 604 TDLLAFVLLHL 614
DLL+F L +
Sbjct: 689 ADLLSFALYEM 699
>dbj|BAA34052.1| (AB010298) prolyl oligopeptidase [Sphingomonas capsulata]
Length = 723
Score = 233 bits (587), Expect = 6e-60
Identities = 179/579 (30%), Positives = 277/579 (46%), Gaps = 59/579 (10%)
Query: 78 GEVIVDSKELEKELNDEVLLQGFTTDEDGKRLAYSFSIGGSDEGITRIIDLETGE-LLEE 136
G V++D K+ L + +DG+ LAYS GGSD + + + G+ L +E
Sbjct: 148 GRVLLDPNTWAKD--GATALDAWAASDDGRLLAYSVQDGGSDWRTVKFVGVADGKPLADE 205
Query: 137 IKPSVWN-IVFL-DKGYYFARFYRKEKTPDGVNPPAERIFWKDEEG-----ERMVFGEGL 189
+K ++ + +L + ++RF ++ + W G ++ VF
Sbjct: 206 LKWVKFSGLAWLGNDALLYSRFAEPKEGQAFQALNYNQTVWLHRLGTPQSADQPVFATPE 265
Query: 190 TSGYFMSLRKSTDGKFAMLTLTYGWNKAEIY---------LGPI-----DKPEEWKKVYS 235
S+DG++ ++T + G + +GP+ D +W
Sbjct: 266 LPKRGHGASVSSDGRWVVITSSEGTDPVNTVHVARVTNGKIGPVTALIPDLKAQW----- 320
Query: 236 ADVPAEPIDVIDGKLYILTKEGKGLGKVIAVKDS----EVEEIIPEGEFPLEWAVIVKDK 291
+ +D + +L+ ++ +G L K++ V S + ++PE + LE I ++
Sbjct: 321 -----DFVDGVGDQLWFVSGDGAPLKKIVRVDLSGSTPRFDTVVPESKDNLESVGIAGNR 375
Query: 292 ILAGRLVHASHKLEVYNLKGEKISEVEFDFPGSLYPLD--KDDERALLRYTSFTVPYRIY 349
+ A + A ++ ++L G+ V GS L D A L ++SFT P +
Sbjct: 376 LFASYIHDAKSQVLAFDLDGKPAGAVSLPGIGSASGLSGRPGDRHAYLSFSSFTQPATVL 435
Query: 350 EFKDEL-KIVEERKVE-----GNFKVEEDFAISKDGTRVHYFIVKGEKDEK---KAWVFG 400
K V +F+VE+ F SKDGT+V FIV+ KD K ++G
Sbjct: 436 ALDPATAKTTPWEPVHLTFDPADFRVEQVFYPSKDGTKVPMFIVR-RKDAKGPLPTLLYG 494
Query: 401 YGGFNISLTPRFFPQVIPFLKRGGIFVMANLRGGSEYGEEWHRAGMRENKQNVFDDFIAV 460
YGGFN++LTP F + ++ GG F +ANLRGG EYG+ WH AG R+ KQNVFDDFIA
Sbjct: 495 YGGFNVALTPWFSAGFMTWIDSGGAFALANLRGGGEYGDAWHDAGRRDKKQNVFDDFIAA 554
Query: 461 LEKLKKEG----YKVAAWGRSNGGLLVSATLVQRPDVMDVALIGYPVIDMLRFHKLYIGS 516
E L G + +A G SNGGLL+ A QRPD+ A V+DMLRF + G
Sbjct: 555 GEWLIANGVTPRHGLAIEGGSNGGLLIGAVTNQRPDLFAAASPAVGVMDMLRFDQFTAGR 614
Query: 517 VWIPEYGNPDDPKDREFLLKYSPYHNVRPQ-EYPPTLIYTGLHDDRVHPAHALKFFMKLK 575
W+ +YG P+ D L +YSPYHNVR +YP L+ T DDRV P H+LK+ L+
Sbjct: 615 YWVDDYGYPEKEADWRVLRRYSPYHNVRSGVDYPAILVTTADTDDRVVPGHSLKYTAALQ 674
Query: 576 EVNA---PVYLRVETKSGHMGASP-ETRARELTDLLAFV 610
P +R+ET++GH P + + E D+ AF+
Sbjct: 675 TAAIGPKPHLIRIETRAGHGSGKPIDKQIEETADVQAFL 713
>emb|CAB40787.1| (AJ238018) prolyl oligopeptidase [Dictyostelium discoideum]
Length = 760
Score = 221 bits (557), Expect = 2e-56
Identities = 199/734 (27%), Positives = 327/734 (44%), Gaps = 141/734 (19%)
Query: 3 DPYIWMENLQDERVLKIVEEENRRFRELVGE--LSDKLFPEVWEYFSQPSIGMARITKRG 60
DPY +E+ Q R K V+EEN+ R + + S+K+ E+ + + R +RG
Sbjct: 30 DPYRHLEDQQSPRTKKWVDEENKITRSFLDQDNTSEKISNEIMKMLNFERFDWFR--RRG 87
Query: 61 IIVSYSEKDRVTVRWLGGEVIVDSKELEKE--------------LNDEVL-------LQG 99
+ +S + + + +D + K+ LN L+
Sbjct: 88 SKLFFSRNPNTLNQNIIYLIDIDQISISKDGKSSAKGFENAIEFLNPNTYSKDGTWSLKS 147
Query: 100 FTTDEDGKRLAYSFSIGGSDE---GITRII---DLETGELLEEIKPSV-------WNIVF 146
F + G + +S+S GSD + +II +L+T + EE K + + +V
Sbjct: 148 FVISKSGDHVCFSYSKAGSDWEEIAVKKIITTNELKTNKDDEEEKEDLKKKNCLHYAVVD 207
Query: 147 L-----------------DKGYYFARFYRKEKTPDG---------------------VNP 168
L + G+ + R+ + EK D N
Sbjct: 208 LPDSINWCKFTSIKWDENETGFIYNRYPKPEKVSDDDKGTETDTNLNNKVYYHKLGDANE 267
Query: 169 PAERIFWKDEEGERMVFGEGLT---SGYFMSLRKSTDGKFAMLTLTYGWNKAEIYLGPID 225
+R+ ++ E + +FG + S F+S + + + + + N E
Sbjct: 268 SFDRVVFECPENPQWIFGTEFSHDHSSLFISAFRDCNVEHNLYVIR---NFQEAIAN--- 321
Query: 226 KPEEWKKVYSADVPAEPIDVI--------DGKLYILTKEGKGLGKVIAVKDSEVEEIIPE 277
K + + + D G+ + LT ++I+++ ++ + I+P
Sbjct: 322 -----KSAFKVEALIDNFDACYYYITNTKQGEYFFLTNLSAPFNRLISIQLNDDQPIVPN 376
Query: 278 GEFPLEWAVIVKDKILAGRLV--------------HASHKLEVYNLKGEKISEVEFDFPG 323
+ LE+ I+ +K V H +EVY+ G+ + +++ PG
Sbjct: 377 SKSKLEFKEIIPEKDYVLESVSRSSPEKFYVSYQKHVQDIIEVYDFNGKYLKDIKLPGPG 436
Query: 324 SL-YPLDKDDERALLRYTSFTVP---YRIYEFKDELKIVEERKVEG----NFKVEEDFAI 375
S + + + +++ P Y + DEL + +E +EG +++ ++ F
Sbjct: 437 SASLSATEYHDHIFINFSNLVSPSVTYYMDSKNDELLLFKEPHIEGFKSSDYECKQVFYE 496
Query: 376 S-KDGTRVHYFIVKGEKDE-----KKAWVFGYGGFNISLTPRFFPQVIPFLKR-GGIFVM 428
S KD T++ FI + + ++ GYGGFNIS T F + I FL + GIFV+
Sbjct: 497 SPKDKTKIPMFIAYKKTTDITSGNAPTYMTGYGGFNISYTQSFSIRNIYFLNKFNGIFVI 556
Query: 429 ANLRGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGY----KVAAWGRSNGGLLVS 484
AN+RGG EYG+ WH AG ++NKQN FDDFI E L KE Y ++A G SNGGLL+
Sbjct: 557 ANIRGGGEYGKAWHEAGSKKNKQNCFDDFIGAAEYLIKENYTNPNQLAVRGGSNGGLLMG 616
Query: 485 ATLVQRPDVMDVALIGYPVIDMLRFHKLYIGSVWIPEYGNPDDPKDREFLLKYSPYHNVR 544
A QRPD+ + V+DMLRFH IGS W+ +YG D+P D E L+KYSP +NV
Sbjct: 617 AISNQRPDLFKCVVADVGVMDMLRFHLHTIGSNWVSDYGRSDNPDDFEVLIKYSPLNNV- 675
Query: 545 PQE---YPPTLIYTGLHDDRVHPAHALKFFMKL-----KEVNAPVYLRVETKSGH-MGAS 595
P++ YP ++ TG HDDRV PAH+ KF +L K+V+ P+ +RV+ SGH G
Sbjct: 676 PKDSNPYPSIMLCTGDHDDRVIPAHSYKFISELQYQLGKKVDTPLLIRVDKDSGHGAGKG 735
Query: 596 PETRARELTDLLAF 609
E+ D+ F
Sbjct: 736 LSKPNNEIADIFNF 749
>gb|AAF88151.1|AC026234_2 (AC026234) Contains similarity to a rPOP protein from Rattus
norvegicus gi|3043760 and is a member of the prolyl
oligopeptidase family PF|00326. ESTs gb|AA651190,
gb|H36145 come from this gene. [Arabidopsis thaliana]
Length = 739
Score = 220 bits (555), Expect = 3e-56
Identities = 201/704 (28%), Positives = 317/704 (44%), Gaps = 116/704 (16%)
Query: 1 MEDPYIWMENLQDERVLKIVEEENRRFRELVG--ELSDKLFPEVWEYFSQPSIGMARITK 58
+ DPY W+E+ E V + VE++ + ++ E +KL + ++ P K
Sbjct: 31 VSDPYRWLEDPDAEEVKEFVEKQVQLSDSVLKSCETKEKLHDKFTKFIDYPRFDTP--FK 88
Query: 59 RGIIVSYSEKDRVTVRWL---------GGEVIVDSKELEKELNDEVLLQGFTTDEDGKRL 109
RG Y + + + E+++D L + V L + ED K L
Sbjct: 89 RGNSYFYFHNSGLQAQSVLHVQDDLESEAEILLDPNTLSDD--GTVSLNTLSISEDAKYL 146
Query: 110 AYSFSIGGSDEGITRIIDLETGEL----LEEIKPSVWNIVFLDKGYYFARFY--RKEKTP 163
AY S GSD +++ +E ++ L +K S KG++++R+ R+ +
Sbjct: 147 AYGLSSSGSDWVTIKVMKIEDKKVEPDSLSWVKFSGITWTHDGKGFFYSRYPAPREGEKI 206
Query: 164 D------------------GVNPPAERIFWKDEEGERMVFGEGLTSGYFMSLRKSTDGKF 205
D G + + + W+D++ + +FG +T DGK+
Sbjct: 207 DAGTETNSNLYHELYYHFLGTDQSEDVLCWRDQDNPKHMFGSKVTD----------DGKY 256
Query: 206 AMLTLTYGWNKA-EIY---LGPIDKPEEWKKVYSADVP-AEPIDVIDGKLYILTKEGKGL 260
++++ G + ++Y L + K E + + +P + ID D + YI + L
Sbjct: 257 LIMSIEEGCDPVNKVYHCDLSLLPKGLEGFRGSNTLLPFVKLIDTFDAQ-YIAIANDETL 315
Query: 261 GKVIAVKDSEVEEIIP-EGEFPLEWAVIVK---------------DKILAGRLVHASHKL 304
+ KD+ +++ + + P W ++ D+++ + H L
Sbjct: 316 FTFLTNKDAPKYKVVRVDLKEPSSWTDVIAEHEKDVLSTASAVNGDQLVVSYMSDVKHIL 375
Query: 305 EVYNLK-GEKISEVEFDFPGSLYPL--DKDDERALLRYTSFTVPYRIY-----EFKDELK 356
++ +LK G + + D GS+ + + D R+TSF P IY E+
Sbjct: 376 QIRDLKSGSLLHGLPVDI-GSVCGVFARRKDTTFFFRFTSFLTPGVIYICDLSHEAPEVT 434
Query: 357 IVEERKVEG----NFKVEEDFAISKDGTRVHYFIVKGEKDEK-----KAWVFGYGGFNIS 407
+ E V G F+V + F SKDGT + FIV KD K ++ YGGF+IS
Sbjct: 435 VFREIGVPGFDRTAFQVTQVFYPSKDGTDIPMFIV-ARKDIKLDGSHPCLLYAYGGFSIS 493
Query: 408 LTPRFFPQVIPFLKR--GGIFVMANLRGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLK 465
+TP FF L R G +F AN+RGG EYGEEWH++G NKQN FDDFI+ E L
Sbjct: 494 MTP-FFSATRIVLGRHLGTVFCFANIRGGGEYGEEWHKSGALANKQNCFDDFISGAEYLV 552
Query: 466 KEGY----KVAAWGRSNGGLLVSATLVQRPDVMDVALIGYPVIDMLRFHKLYIGSVWIPE 521
GY K+ G SNGG+LV A + QRPD+ AL V+DMLRFHK IG W E
Sbjct: 553 SAGYTQPRKLCIEGGSNGGILVGACINQRPDLFGCALAHVGVMDMLRFHKFTIGHAWTSE 612
Query: 522 YGNPDDPKDREFLLKYSPYHNV-RPQE--------YPPTLIYTGLHDDRVHPAHALKFFM 572
+G D ++ +L+KYSP HNV RP E YP T++ T HDDRV P H+ K
Sbjct: 613 FGCSDKEEEFHWLIKYSPLHNVKRPWEQKTDLFFQYPSTMLLTADHDDRVVPLHSYKLLA 672
Query: 573 KLK----------EVNAPVYLRVETKSGHMGASPETRARELTDL 606
++ P+ R+E K+GH P + + +L
Sbjct: 673 TMQYELGLSLENSPQTNPIIARIEVKAGHGAGRPTQKMCNVCEL 716
>gb|AAF57241.1| (AE003782) CG2528 gene product [Drosophila melanogaster]
Length = 723
Score = 207 bits (521), Expect = 3e-52
Identities = 175/533 (32%), Positives = 254/533 (46%), Gaps = 69/533 (12%)
Query: 104 EDGKRLAYSFSIGGSDEGITRIIDLETG----ELLEEIKPSVWNIVFLDKGYYFARFYRK 159
EDG +AY S GSD RI + + G E+LE++K S + KG+++ R+ +
Sbjct: 196 EDGAFMAYGLSESGSDWNKIRIRNTKEGIDLPEILEKVKFSNVSWTKDSKGFFYGRYTDQ 255
Query: 160 EKTPDGVNPPAERIFWKDEEGERMVFGEGLTSGYFM-------SLRKSTD----GKFAML 208
DG+ +E ++++ + GE + S R TD GK+ +L
Sbjct: 256 ----DGIFDGSETKLAENQKLYYHLLGESPHQDILIAEFPEHPSWRFKTDISDCGKYLIL 311
Query: 209 TLTYGWNKAEIYLGPIDKPEEWKKVYSADVPAEPI-DVIDGKLYILTKEGKGLG------ 261
++++ +Y + E K + ++ +PI D + +T EG L
Sbjct: 312 SISHTVRDNMLYYAELGSEE--KNAFQLEL--KPIVDKFEADFDYITNEGSNLYFHTNKD 367
Query: 262 ----KVIAVKDSEVEEI-----IPEGEFP-LEWAVIVK-DKILAGRLVHASHKLEVYNLK 310
+VI + + E IPE + LEWA V +K++ H L+ +L
Sbjct: 368 APNYRVIVIDVNNPAEEHWTTPIPEHKKDVLEWAKCVDGNKLVVCYNCDVKHILQARDLS 427
Query: 311 -GEKISEVEFDFPGSLYPLD--KDDERALLRYTSFTVPYRI--YEFKD---------ELK 356
G+ I + D GS+ + K + ++SF P I Y+F E+
Sbjct: 428 TGKLIRQFGLDI-GSINGISGKKSNSEIFYGFSSFLSPGIIFYYDFAKPSEKPTVLREIS 486
Query: 357 IVEERKVEGNFKVEEDFAISKDGTRVHYFIVKGEKD---EKKAWVFGYGGFNISLTPRFF 413
+ E N+ VE+ F S D T + FIV+ ++D + ++GYGGFN SL P F
Sbjct: 487 LNLEGFSRDNYSVEQVFYKSTDDTDIPMFIVQRKRDIAEPRPCLLYGYGGFNYSLMPSFG 546
Query: 414 PQVIPFLKR-GGIFVMANLRGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGY--- 469
+ F+ G+ NLRGG EYG EWH G +KQNVF+DF A E L K Y
Sbjct: 547 ILSLMFMDTFDGVLAFPNLRGGGEYGMEWHNGGRMLSKQNVFNDFQAAAEFLTKNNYTTK 606
Query: 470 -KVAAWGRSNGGLLVSATLVQRPDVMDVALIGYPVIDMLRFHKLYIGSVWIPEYGNPDDP 528
++A G SNGGLLV A + QRPD+ A+ V+DMLRFHK IG W +YGNPD+
Sbjct: 607 DRLAIQGASNGGLLVGACINQRPDLFGAAVAQVGVMDMLRFHKFTIGHAWCSDYGNPDEK 666
Query: 529 KDREFLLKYSPYHNVR-----PQEYPPTLIYTGLHDDRVHPAHALKFFMKLKE 576
L+K+SP HNV QEYP TLI T HDDRV P H+ KF L+E
Sbjct: 667 VHFANLIKFSPLHNVHIPLNPNQEYPSTLILTADHDDRVSPLHSYKFVAALQE 719
>gi|11419026 prolyl endopeptidase [Homo sapiens]
Length = 259
Score = 194 bits (487), Expect = 3e-48
Identities = 103/233 (44%), Positives = 141/233 (60%), Gaps = 18/233 (7%)
Query: 396 AWVFGYGGFNISLTPRFFPQVIPFLKR-GGIFVMANLRGGSEYGEEWHRAGMRENKQNVF 454
A+++GYGGFNIS+TP + + F++ GGI +AN+RGG EYGE WH+ G+ NKQN F
Sbjct: 17 AFLYGYGGFNISITPNYSVSRLIFVRHMGGILAVANIRGGGEYGETWHKGGILANKQNCF 76
Query: 455 DDFIAVLEKLKKEGY----KVAAWGRSNGGLLVSATLVQRPDVMDVALIGYPVIDMLRFH 510
DDF E L KEGY ++ G SNGGLLV+A QRPD+ + V+DML+FH
Sbjct: 77 DDFQCAAEYLIKEGYTSPKRLTINGGSNGGLLVAACANQRPDLFGCVIAQVGVMDMLKFH 136
Query: 511 KLYIGSVWIPEYGNPDDPKDREFLLKYSPYHNVRPQE-----YPPTLIYTGLHDDRVHPA 565
K IG W +YG D + E+L+KYSP HNV+ E YP L+ T HDDRV P
Sbjct: 137 KYTIGHAWTTDYGCSDSKQHFEWLVKYSPLHNVKLPEADDIQYPSMLLLTADHDDRVVPL 196
Query: 566 HALKFFMKLKEV-------NAPVYLRVETKSGHMGASPETRA-RELTDLLAFV 610
H+LKF L+ + + P+ + V+TK+GH P + E++D+ AF+
Sbjct: 197 HSLKFIATLQYIVGRSRKQSNPLLIHVDTKAGHGAGKPTAKVIEEVSDMFAFI 249
>pir||C81033 prolyl oligopeptidase family protein NMB1877 [imported] - Neisseria
meningitidis (group B strain MD58)
>gi|7227135|gb|AAF42211.1| (AE002537) prolyl
oligopeptidase family protein [Neisseria meningitidis
MC58]
Length = 671
Score = 185 bits (464), Expect = 2e-45
Identities = 172/599 (28%), Positives = 261/599 (42%), Gaps = 92/599 (15%)
Query: 79 EVIVDSKELEKELNDEVLLQGFT-TDEDGKRLAYSFSIGGSDEGITRIIDLETGELLEEI 137
+++ + ++ L D+V L G + E R + S GSD T +DLE GEL+E
Sbjct: 97 KILFSVADFDELLGDDVYLGGVSHLVEQPNRALLTLSKLGSDTAYTLEVDLEAGELVEG- 155
Query: 138 KPSVWNIVFLDKGYYFARFYRKEKTPDGVNPPAERIFWKDEEG--------ERMVFGEGL 189
G++F P G N + W+DE ER + G
Sbjct: 156 ------------GFHF---------PAGKN----HVSWRDENSVWVCPAWNERQLTQSGY 190
Query: 190 TSGYFMSLR-KSTDGKFAMLTL------TYGWNKAEIYLGPIDKPEE----WKKVY---S 235
++ R KS + + + W + PID E + K Y S
Sbjct: 191 PREVWLVERGKSFEESLPVYQIGEDGMMVNAWRYLDPQGSPIDLIEASDGFYTKTYLRVS 250
Query: 236 ADVPAEPIDV---------IDGKLYILTK-------EGKGLGKVIAVKDSEVEE------ 273
A+ A+P+++ + G L + + + G ++AVK + E
Sbjct: 251 AEGEAKPLNLPNDCDVVGYLAGHLLLTLRKDWNRANQSYPSGALVAVKLNRGELGAAQLL 310
Query: 274 IIPEGEFPLEWAVIVKDKILAGRLVHASHKLEVYNLKGEKISEVEFDF--PGSLYPLDKD 331
P+ LE K ++A L + +L+ + K EVE G+L D+
Sbjct: 311 FAPDETQALESVETTKRFVVASLLENVQGRLKAWRFADGKWQEVELPRLPSGALEMTDQP 370
Query: 332 --DERALLRYTSFTVPYRIYEFK---DELKIVEERKVE---GNFKVEEDFAISKDGTRVH 383
+ L + FT P ++ EL ++ + + V++ + S DG R+
Sbjct: 371 WGGDVVYLAASDFTTPLTLFALDLNVMELTVMRRQPQQFDSDGINVQQFWTTSADGERIP 430
Query: 384 YFIV-KGEKDEKKAWVFGYGGFNISLTPRFFPQVIPF-LKRGGIFVMANLRGGSEYGEEW 441
YF V K + V+ YGGF I P + + + L+ G FV+AN+RGG E+G W
Sbjct: 431 YFHVGKNAAPDMPTLVYAYGGFGIPELPHYLGSIGKYWLEEGNAFVLANIRGGGEFGPRW 490
Query: 442 HRAGMRENKQNVFDDFIAVLEKLKKEGYK----VAAWGRSNGGLLVSATLVQRPDVMDVA 497
H+A +K DD +AV+ L + G + G SNGGL+ +A V+ P +
Sbjct: 491 HQAAQGISKHKSVDDLLAVVRDLSERGISSPEHIGLQGGSNGGLITAAAFVREPQSIGAL 550
Query: 498 LIGYPVIDMLRFHKLYIGSVWIPEYGNPDDPKD-REFLLKYSPYHNVRPQ-EYPPTLIYT 555
+ P+ DM+R+ L GS W EYGNP + + L + SPYHN+ +YPP LI T
Sbjct: 551 VCEVPLTDMIRYPLLSAGSSWTDEYGNPQKYEVCKRRLGELSPYHNLSDGIDYPPALITT 610
Query: 556 GLHDDRVHPAHALKFFMKLKEVNAPVYLRVETKSGHMGASPETRARELTDLLAFVLLHL 614
L DDRVHPAHALKF+ KL+E +A +L GH G + RE D LA VLL L
Sbjct: 611 SLSDDRVHPAHALKFYAKLRETSAQSWLYSPDGGGHTGNGTQ---RESADELACVLLFL 666
>pir||B70528 probable peptidase - Mycobacterium tuberculosis (strain H37RV)
>gi|3261799|emb|CAB09571.1| (Z96796) hypothetical
protein Rv0457c [Mycobacterium tuberculosis]
Length = 673
Score = 183 bits (459), Expect = 6e-45
Identities = 109/323 (33%), Positives = 161/323 (49%), Gaps = 16/323 (4%)
Query: 289 KDKILAGRLVHASHKLEVY---NLKGEKISEVEFDFPGSLYPLDKDDERALLRYTSFTVP 345
+D++L L + ++E+ + + E +S + + D + L + F P
Sbjct: 329 RDRLLIVTLADVASRVEIATPGSWRREPLSGIPAATNTVIVSADSHGDEFFLDSSGFDTP 388
Query: 346 YRIYEFKDELKIVEERKVEG-----NFKVEEDFAISKDGTRVHYFIVKGEKDEKKAWVF- 399
R+ D+ ++ E + N V + FA S DGT + YF+V+ +
Sbjct: 389 SRLMRGTDDGRLAEIKSAPAFFDAENMAVTQYFATSDDGTSIPYFVVRRTDADNPGPTLL 448
Query: 400 -GYGGFNISLTPRFFPQVIP-FLKRGGIFVMANLRGGSEYGEEWHRAGMRENKQNVFDDF 457
GYGGF S TP + + +L RGG + +AN+RGG EYG WH MRE + V DF
Sbjct: 449 NGYGGFETSRTPTYDGVLGRLWLARGGTYALANIRGGGEYGPGWHTQAMREGRDKVAQDF 508
Query: 458 IAVLEKLKKEGYKVA----AWGRSNGGLLVSATLVQRPDVMDVALIGYPVIDMLRFHKLY 513
AV L G A A G SNGGLL+ L P+ + P++DM R+H L
Sbjct: 509 AAVATDLVTRGITTAEQLGARGGSNGGLLMGIMLTGYPEKFGALVCDVPLLDMKRYHLLL 568
Query: 514 IGSVWIPEYGNPDDPKDREFLLKYSPYHNVRP-QEYPPTLIYTGLHDDRVHPAHALKFFM 572
G+ W+ EYG+PD+P D +F+ +YSPY N+ ++YPP L+ T DDRVHP HA K
Sbjct: 569 AGASWMAEYGDPDNPDDWKFISEYSPYQNISANRKYPPVLMTTSTRDDRVHPGHARKMTA 628
Query: 573 KLKEVNAPVYLRVETKSGHMGAS 595
L+ PV+ + GH GA+
Sbjct: 629 ALQAAGHPVWYYENIEGGHAGAA 651
>pir||H81976 probable prolyl oligopeptidase (EC 3.4.21.26) NMA0579 [imported] -
Neisseria meningitidis (group A strain Z2491)
>gi|7379315|emb|CAB83870.1| (AL162753) putative prolyl
endopeptidase [Neisseria meningitidis Z2491]
Length = 671
Score = 181 bits (454), Expect = 2e-44
Identities = 169/599 (28%), Positives = 257/599 (42%), Gaps = 92/599 (15%)
Query: 79 EVIVDSKELEKELNDEVLLQGFT-TDEDGKRLAYSFSIGGSDEGITRIIDLETGELLEEI 137
+++ + ++ L D+V L G + E R + S G D T +DLE GEL+E
Sbjct: 97 KILFSVADFDELLGDDVYLGGVSHLVEQPNRALLTLSKSGGDTAYTLEVDLEAGELVEG- 155
Query: 138 KPSVWNIVFLDKGYYFARFYRKEKTPDGVNPPAERIFWKDEEG--------ERMVFGEGL 189
G++F P G N + W+DE ER + G
Sbjct: 156 ------------GFHF---------PAGKN----HVSWRDENSVWVCPAWDERQLTESGY 190
Query: 190 TSGYFMSLR-KSTDGKFAMLTLTY------GWNKAEIYLGPIDKPEE----WKKVY---S 235
++ R KS + + + W + PID E + K Y S
Sbjct: 191 PREVWLVERGKSFEESLPVYQIAEDGMMVNAWRYLDPQGSPIDLIEASDGFYTKTYLQVS 250
Query: 236 ADVPAEPIDV---------IDGKLYILTK-------EGKGLGKVIAVKDSEVEE------ 273
A+ A+P+++ + G L + + + G ++AVK + E
Sbjct: 251 AEGEAKPLNLPNDCDVVGYLAGHLLLTLRKDWHRANQSYPSGALVAVKLNRGELGAAQLL 310
Query: 274 IIPEGEFPLEWAVIVKDKILAGRLVHASHKLEVYNLKGEKISEVEFDF--PGSLYPLDKD 331
P LE K ++A L + +L+ + K E E G+L D+
Sbjct: 311 FAPNETQALESVETTKRFVVASLLENVQGRLKAWRFTDGKWQETELPRLPSGALEMTDQP 370
Query: 332 --DERALLRYTSFTVPYRIYEFK---DELKIVEERKVE---GNFKVEEDFAISKDGTRVH 383
+ L + FT P ++ EL ++ + + V++ + S DG R+
Sbjct: 371 WGGDVVYLAASDFTTPLTLFALDLNVMELTVMRRQPQQFDSDGINVQQFWTTSADGERIP 430
Query: 384 YFIV-KGEKDEKKAWVFGYGGFNISLTPRFFPQVIPF-LKRGGIFVMANLRGGSEYGEEW 441
YF V K + V+ YGGF I P + + + L+ G FV+AN+RGG E+G W
Sbjct: 431 YFHVGKNAAPDMPTLVYAYGGFGIPELPHYLGSIGKYWLEEGNAFVLANIRGGGEFGPRW 490
Query: 442 HRAGMRENKQNVFDDFIAVLEKLKKEGYK----VAAWGRSNGGLLVSATLVQRPDVMDVA 497
H+A +K DD +AV+ L + G + G SNGGL+ +A V+ P +
Sbjct: 491 HQAAQGISKHKSVDDLLAVVSDLSERGISSPEHIGLQGGSNGGLITAAAFVREPQSIGAL 550
Query: 498 LIGYPVIDMLRFHKLYIGSVWIPEYGNPDDPKD-REFLLKYSPYHNVRPQ-EYPPTLIYT 555
+ P+ DM+R+ L GS W EYGNP + + L + SPYHN+ +YPP LI T
Sbjct: 551 VCEVPLTDMIRYPLLSAGSSWTDEYGNPQKYEVCKRRLGELSPYHNLSDGIDYPPALITT 610
Query: 556 GLHDDRVHPAHALKFFMKLKEVNAPVYLRVETKSGHMGASPETRARELTDLLAFVLLHL 614
L DDRVHPAHALKF+ KL+E + +L GH G + RE D LA VLL L
Sbjct: 611 SLSDDRVHPAHALKFYAKLRETSPQSWLYSPDGGGHTGNGTQ---REAADELACVLLFL 666
>sp|Q59536|PTRB_MORLA PROTEASE II (OLIGOPEPTIDASE B) >gi|1084058|pir||JC4185 proteinase
II (EC 3.4.21.-) - Moraxella lacunata
>gi|551625|dbj|BAA07460.1| (D38405) protease II
[Moraxella lacunata]
Length = 690
Score = 179 bits (449), Expect = 9e-44
Identities = 180/679 (26%), Positives = 300/679 (43%), Gaps = 93/679 (13%)
Query: 2 EDPYIWMENLQDERVLKIVEEENRRFRELVGELSDKLFPEVWEYFSQ--PSIGMARITKR 59
ED Y W+++ + V++ +EEENR + E++ L ++ +++E P M +
Sbjct: 21 EDDYYWLKDRDNTEVIQYLEEENRYYHEIMRPLQEQT-EQIYESMVDRVPDSEMKVPVQH 79
Query: 60 GIIVSYSEKD---------------RVTVRWLGGEVIVDSKELEKELND-EVLLQGFTTD 103
G YS D R ++ EV++D EL +E + V +Q TTD
Sbjct: 80 GQFFYYSRLDKNKQYPIYARKQAASRALLQDATEEVVLDLNELAEEDDYLSVTVQRMTTD 139
Query: 104 EDGKRLAYSFSIGGSDEGITRIIDLETGELLEEIKPSVWNIVFLDKGYYFARFYRKEKTP 163
RLAY + G+D I DL TGELL + P+V+ ++ + Y T
Sbjct: 140 HS--RLAYLENRDGTDRYTIYIKDLNTGELLSDRVPNVY--IYGSMEWCRCGDYIFYTTV 195
Query: 164 DGVNPPAERIFWK-----DEEGERMVFGEGLTSGYFMSLRKSTDGKFAMLTLTYGWNKAE 218
D P + W+ D E + ++F E + + + KS GKF + Y +K
Sbjct: 196 DEHQRPCQ--LWRHRLGSDVESDELIFEEK-DDTFTLFISKSQSGKFIFV---YSSSKTT 249
Query: 219 IYLGPIDKPEEWKKVYSADVPAEPIDVIDGK--------------LYILTKEGKGLGKVI 264
+ ID D P P+ ++D + L ILT EG +++
Sbjct: 250 SEIHMID----------TDSPLSPLQLVDERRDGILYDVEHWEDDLLILTNEGALNFQLL 299
Query: 265 AVK----DSEVEEIIPEGEFPLEWAVIVKDKIL-AGRLVHASHKLEVYNLKGEKISEVEF 319
S+V + E L+ +DK+L AGR + +++ + ++ ++ +
Sbjct: 300 RCPLNDLSSKVNVVEYNEERYLQEMYPFRDKLLIAGR---ENGLTQIWVVHDGELQQISW 356
Query: 320 DFP----GSLYPLDKDDERALLRYTSFTVPYRIYEFK---DELKIVEERKVEGN-----F 367
D P L D L++Y S P + E + ++ V G F
Sbjct: 357 DEPLYTVAVLSEQSYDTNEVLIQYESLLTPKTTFGLNLQTGEKQCLQVAPVSGEYDRSQF 416
Query: 368 KVEEDFAISKDGTRVHYFIV--KGEKDEKKA--WVFGYGGFNISLTPRFFPQVIPFLKRG 423
+ E+ +A + G +V V +G D A ++GYG + + PRF P +P L++G
Sbjct: 417 RQEQLWATGRSGVKVPMTAVYLEGALDNGPAPLILYGYGSYGSNSDPRFDPYRLPLLEKG 476
Query: 424 GIFVMANLRGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGY----KVAAWGRSNG 479
+FV A +RGGSE G W+ G +NK+N F DFIA + L + Y K+AA G S G
Sbjct: 477 IVFVTAQVRGGSEMGRGWYEDGKMQNKRNTFTDFIAAAKHLIDQNYTSPTKMAARGGSAG 536
Query: 480 GLLVSATLVQRPDVMDVALIGYPVIDMLRF---HKLYIGSVWIPEYGNPDDPKDREFLLK 536
GLLV A ++ V + P +D++ + + ++ E+G+P +D ++
Sbjct: 537 GLLVGAVANMAGELFKVIVPAVPFVDVVTTMLDTSIPLTTLEWDEWGDPRKQEDYFYMKS 596
Query: 537 YSPYHNVRPQEYPPTLIYTGLHDDRVHPAHALKFFMKLKEV---NAPVYLRVETKSGHMG 593
YSPY NV ++YP I TG++D RV K+ +L+ V N + ++ +GH G
Sbjct: 597 YSPYDNVEAKDYPHMYITTGINDPRVGYFEPAKWVARLRAVKTDNNTLVMKTNMGAGHFG 656
Query: 594 ASPE-TRARELTDLLAFVL 611
S +E + AF+L
Sbjct: 657 KSGRFNHLKEAAESYAFIL 675
>sp|P55577|Y4NA_RHISN PROBABLE PEPTIDASE Y4NA >gi|2182536|gb|AAB91781.1| (AE000086) Y4nA
[Rhizobium sp. NGR234]
Length = 726
Score = 175 bits (438), Expect = 2e-42
Identities = 92/242 (38%), Positives = 138/242 (57%), Gaps = 12/242 (4%)
Query: 365 GNFKVEEDFAISKDGTRVHYFIVKGEKDEK-----KAWVFGYGGFNISLTPRFFPQVIP- 418
G + ++ +A SKDGT+V YF+V KD K ++ YGGF I + P + +
Sbjct: 462 GGLQAQQFWATSKDGTKVPYFLV-ARKDVKLDGTNPTILYAYGGFQIPMQPSYSAVLGKL 520
Query: 419 FLKRGGIFVMANLRGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGYK----VAAW 474
+L++GG + +AN+RGG E+G +WH AG++ N+Q V+DDF AV + L + +
Sbjct: 521 WLEKGGAYALANIRGGGEFGPKWHDAGLKTNRQRVYDDFQAVAQDLIAKKVTSTPHLGIM 580
Query: 475 GRSNGGLLVSATLVQRPDVMDVALIGYPVIDMLRFHKLYIGSVWIPEYGNPDDPKDREFL 534
G SNGGLL+ ++QRPD+ + +I P++DM+ F ++ G+ W EYG+PDDP + FL
Sbjct: 581 GGSNGGLLMGVQMIQRPDLWNAVVIQVPLLDMVNFTRMSAGASWQAEYGSPDDPVEGAFL 640
Query: 535 LKYSPYHNVRP-QEYPPTLIYTGLHDDRVHPAHALKFFMKLKEVNAPVYLRVETKSGHMG 593
SPYHNV+ YP T DDRV P HA K +++ P Y + GH
Sbjct: 641 RSISPYHNVKAGVAYPEPFFETSTKDDRVGPVHARKMAALFEDMGLPFYYYENIEGGHAA 700
Query: 594 AS 595
A+
Sbjct: 701 AA 702
>emb|CAB39326.1| (AJ000250) hypothetical protein [Neisseria meningitidis]
Length = 641
Score = 167 bits (419), Expect = 3e-40
Identities = 156/561 (27%), Positives = 242/561 (42%), Gaps = 89/561 (15%)
Query: 79 EVIVDSKELEKELNDEVLLQGFT-TDEDGKRLAYSFSIGGSDEGITRIIDLETGELLEEI 137
+++ + ++ L D+V L G + E R + S G D T +DLE GEL+E
Sbjct: 97 KILFSVADFDELLGDDVYLGGVSHLVEKPDRALLTLSKSGGDTAYTLEVDLEAGELVEG- 155
Query: 138 KPSVWNIVFLDKGYYFARFYRKEKTPDGVNPPAERIFWKDEEG--------ERMVFGEGL 189
G++F P G N + W+DE ER + G
Sbjct: 156 ------------GFHF---------PAGKN----HVSWRDENSVWVCPAWDERQLTESGY 190
Query: 190 TSGYFMSLR-KSTDGKFAMLTL------TYGWNKAEIYLGPIDKPEE----WKKVY---S 235
++ R KS + + + W + PID E + K Y S
Sbjct: 191 PREVWLVERGKSFEESLPVYQIGEDGMMVNAWRYLDPQGSPIDLIEASDGFYTKTYLQVS 250
Query: 236 ADVPAEPIDV---------IDGKLYILTK-------EGKGLGKVIAVKDSEVEE------ 273
A+ A+P+++ + G L + + + G ++AVK + E
Sbjct: 251 AEGEAKPLNLPADCDVVGYLAGHLLLTLRKDWHRANQSYPSGALVAVKLNRGEIGAAQLL 310
Query: 274 IIPEGEFPLEWAVIVKDKILAGRLVHASHKLEVYNLKGEKISEVEFDF--PGSLYPLDKD 331
P+ LE K ++A L + +L+ + K E E G+L D+
Sbjct: 311 FAPDETQALESVETTKRFVVASLLENVQGRLKAWRFTDGKWQEAELPRLPSGALEMTDQP 370
Query: 332 --DERALLRYTSFTVPYRIYEFK---DELKIVEERKVE---GNFKVEEDFAISKDGTRVH 383
+ L + FT P ++ EL ++ + + V++ + S DG R+
Sbjct: 371 WGGDVVYLAASDFTTPLTLFALDLNVMELTVMRRQPQQFDSDGINVQQFWTTSADGERIP 430
Query: 384 YFIV-KGEKDEKKAWVFGYGGFNISLTPRFFPQVIPF-LKRGGIFVMANLRGGSEYGEEW 441
YF V K + V+ YGGF I P + V + L+ G FV+AN+RGG E+G W
Sbjct: 431 YFHVGKNAAPDTPTLVYAYGGFGIPELPHYLGSVGKYWLEEGNAFVLANIRGGGEFGPRW 490
Query: 442 HRAGMRENKQNVFDDFIAVLEKLKKEGYK----VAAWGRSNGGLLVSATLVQRPDVMDVA 497
H+A +K DD +AV+ L + G + G SNGGL+ +A V+ P +
Sbjct: 491 HQAAQGISKHKSVDDLLAVVRDLSERGISSPQHIGLQGGSNGGLITAAAFVREPQSIGAL 550
Query: 498 LIGYPVIDMLRFHKLYIGSVWIPEYGNPDDPKDREFLL-KYSPYHNVRPQ-EYPPTLIYT 555
+ P+ DM+R+ L G+ W EYGNP + + L + SPYHN+ +YPP LI T
Sbjct: 551 VCEVPLTDMIRYPLLSAGASWTDEYGNPQKYEVCKCRLGELSPYHNLSDGIDYPPALITT 610
Query: 556 GLHDDRVHPAHALKFFMKLKE 576
L DDRVHPAHALKF+ KL+E
Sbjct: 611 SLSDDRVHPAHALKFYAKLRE 631
>sp|P81171|Y174_RICPR PROBABLE PEPTIDASE RP174 >gi|7467917|pir||B71728 probable peptidase
y4na (ppcE) RP174 - Rickettsia prowazekii
>gi|3860740|emb|CAA14641.1| (AJ235270) PROBABLE
PEPTIDASE Y4NA (ppcE) [Rickettsia prowazekii]
Length = 722
Score = 167 bits (418), Expect = 4e-40
Identities = 106/329 (32%), Positives = 174/329 (52%), Gaps = 23/329 (6%)
Query: 289 KDKILAGRLVHASHKLEVYNLKGEKISE---VEFDFPGSLYPLD--KDDERALLRYTSFT 343
KD++ + K+ + L+ E+ ++ ++ + +++ + +D+E AL+ +
Sbjct: 368 KDRVFLATYDNVVSKVVTFTLENEQWTKPVILKLPYQNAIFRMSSYEDEEEALITIENAI 427
Query: 344 VPYRIYEF--KDELKIVEERKVE---GNFKVEEDFAISKDGTRVHYFIV--KGEKDEKK- 395
VP IY + ELK++ + N+ +E+ A S DG ++ YFIV KG K + K
Sbjct: 428 VPPTIYLWVKTHELKVIRKALYSFDSENYVLEQKEATSFDGVKIPYFIVYKKGIKFDGKN 487
Query: 396 -AWVFGYGGFNISLTPRFFPQVIP--FLKRGGIFVMANLRGGSEYGEEWHRAGMRENKQN 452
+ YGGF + +P +F ++ ++K GG+ V+AN+RGG E+G EWH+A +Q
Sbjct: 488 PTLLEAYGGFQVINSP-YFSRIKNEVWVKNGGVSVLANIRGGGEFGPEWHKAAQGIKRQT 546
Query: 453 VFDDFIAVLEKLKKEGYKVAAW----GRSNGGLLVSATLVQRPDVMDVALIGYPVIDMLR 508
F+DF AV E+L K+ + G SNGGLLVS + QRP++ P++DM+R
Sbjct: 547 AFNDFFAVSEELIKQNITSPEYLGIKGGSNGGLLVSVAMTQRPELFGAIACEVPILDMIR 606
Query: 509 FHKLYIGSVWIPEYGNPDDPKDREFLLKYSPYHNVR-PQEYPPTLIYTGLHDDRVHPAHA 567
+ + G+ W+ EYG+P+ P D + KY+P N+ Q+YP LI + D RVHP H
Sbjct: 607 YKEFGAGNSWVTEYGDPEIPNDLLHIKKYAPLENLSLTQKYPTVLITDSVLDQRVHPWHG 666
Query: 568 LKF-FMKLKEVNAPVYLRVETKSGHMGAS 595
F ++ + N Y SGH S
Sbjct: 667 RIFEYVLAQNPNTKTYFLESRDSGHSSGS 695
>gb|AAC80459.1| (AF078916) oligopeptidase B [Trypanosoma brucei brucei]
Length = 715
Score = 164 bits (412), Expect = 2e-39
Identities = 138/409 (33%), Positives = 199/409 (47%), Gaps = 46/409 (11%)
Query: 250 LYILTKEGKGL-GKVIAVKDSEVEE----IIPEGEFPL--EWAVIVKDKILAGRLVHASH 302
L +LT + K + GKV+ K S + +IP + + AV K +L+GR +
Sbjct: 301 LIVLTNKDKCVNGKVVLTKRSAPTDWGTVLIPHDDKVTIDDVAVFAKFAVLSGRRDGLTR 360
Query: 303 ----KLEVYNL-KGEKISEVEFDFPGSLYPL------DKDDERALLRYTSFTVPYRIYE- 350
+L NL + E+ FD P + D LRY+S T P Y+
Sbjct: 361 VWTVRLGPDNLFSSATLKELHFDEPVFTAHVVCSQMKTYDASLLRLRYSSMTTPTVWYDE 420
Query: 351 --FKDELKIVEERKVEGNFKVEE-----DFAISKDGTRVHYFIVKGEKDEKK----AWVF 399
E K+V+ RKV G F+ + + A + DGT+V +V + K ++
Sbjct: 421 DVLSGERKVVKARKVGGGFESKNYVCRRELATAPDGTKVPISLVYDTSIDLKKPNPTMLY 480
Query: 400 GYGGFNISLTPRFFPQVIPFLKRGGIFVMANLRGGSEYGEEWHRAGMRE-NKQNVFDDFI 458
GYG + I + P F + +P++ RG I+ +A++RGG E G W+ G + K+N F DFI
Sbjct: 481 GYGSYGICIEPEFNSRFLPYVDRGMIYAIAHVRGGGEMGRTWYEVGGKYLTKRNTFMDFI 540
Query: 459 AVLEKLKKEGYKVAAW----GRSNGGLLVSATLVQRPDVMDVALIGYPVIDMLRFH---- 510
A E L G A GRS GGLLV A L RPD+ VAL G P +D++
Sbjct: 541 ACAEHLISSGLTTPAQLSCEGRSAGGLLVGAVLNMRPDLFHVALAGVPFVDVMTTMCDPS 600
Query: 511 -KLYIGSVWIPEYGNPDDPKDREFLLKYSPYHNVRPQEYPPTLIYTGLHDDRVHPAHALK 569
L G W E+GNP++ K +++ YSP NVR Q+YP +I GLHD RV K
Sbjct: 601 IPLTTGE-W-EEWGNPNEYKFFDYMNSYSPIDNVRAQDYPHLMIQAGLHDPRVAYWEPAK 658
Query: 570 FFMKLKEVNA---PVYLRVETKSGHMGASPETR-ARELTDLLAFVLLHL 614
+ KL+E+ V L+++ +SGH AS + RE AFVL HL
Sbjct: 659 WASKLRELKTDSNEVLLKMDLESGHFSASDRYKYLRENAIQQAFVLKHL 707
>gb|AAD24761.1|AF109875_1 (AF109875) oligopeptidase B [Leishmania major]
Length = 731
Score = 160 bits (400), Expect = 5e-38
Identities = 129/437 (29%), Positives = 203/437 (45%), Gaps = 59/437 (13%)
Query: 207 MLTLTYGWNKAEIYLGPIDKPEEWKKV---YSADVPAEPIDVIDGKLYILTKEGKGLGKV 263
+LT G ++ + P +P +W V +S DV E I V L + + GL ++
Sbjct: 315 ILTNEGGAVNHKLLIAPRGQPSDWSHVLVDHSEDVFMESIAVRSNYLVVAGRRA-GLTRI 373
Query: 264 IAVKDSEVEEIIPEGEFPLEWAVIVKDKILAGRLVHASHKLEVYNLKGEKISEVEFDFPG 323
+ + + G E V++++ I LV +
Sbjct: 374 WTMMADSQDGVFQAGTGLRE--VVMEEPIFTVHLVESQM--------------------- 410
Query: 324 SLYPLDKDDERALLRYTSFTVPYRIYEFKDE---LKIVEERKVEG-----NFKVEEDFAI 375
L+ ++ + Y+S P ++ + +V+ R+V G N+KVE FA
Sbjct: 411 ----LEYEEPTFRMEYSSLATPNTWFDVSPQDTLAPLVKVREVGGGFDAANYKVERRFAT 466
Query: 376 SKDGTRVHYFIVKGE----KDEKKAWVFGYGGFNISLTPRFFPQVIPFLKRGGIFVMANL 431
+ D T++ +V + + ++GYG + +S+ P+F Q +P+ RG IF +A++
Sbjct: 467 APDQTKIPLSVVCHKDLDMSQPQPCMLYGYGSYGLSMDPQFSIQHLPYCDRGMIFAIAHI 526
Query: 432 RGGSEYGEEWHRAGMRE-NKQNVFDDFIAVLEKLKKEGY----KVAAWGRSNGGLLVSAT 486
RGGSE G W+ G + K+N F DFIA E L ++A GRS GGLL+ A
Sbjct: 527 RGGSELGRAWYEIGAKYLTKRNTFSDFIAAAEFLVNAKLTTPSQLACEGRSAGGLLMGAV 586
Query: 487 LVQRPDVMDVALIGYPVIDMLRFH-----KLYIGSVWIPEYGNPDDPKDREFLLKYSPYH 541
L RPD+ VAL G P +D++ L G W E+GNP++ K +++L YSP
Sbjct: 587 LNMRPDLFKVALAGVPFVDVMTTMCDPSIPLTTGE-W-EEWGNPNEYKYYDYMLSYSPMD 644
Query: 542 NVRPQEYPPTLIYTGLHDDRVHPAHALKFFMKLKEV---NAPVYLRVETKSGHMGASPET 598
NVR QEYP ++ GLHD RV K+ KL+E N + L ++ +SGH A
Sbjct: 645 NVRAQEYPNIMVQCGLHDPRVAYWEPAKWVSKLRECKTDNNEILLNIDMESGHFSAKDRY 704
Query: 599 RA-RELTDLLAFVLLHL 614
+ +E AFV HL
Sbjct: 705 KFWKESAIQQAFVCKHL 721
>gb|AAC80228.1| (U69897) oligopeptidase B [Trypanosoma cruzi]
Length = 714
Score = 158 bits (396), Expect = 2e-37
Identities = 186/698 (26%), Positives = 297/698 (41%), Gaps = 114/698 (16%)
Query: 3 DPYIWM--ENLQDERVLKIVEEENRRFRELVGELSD---KLFPEVWEYFSQPSI------ 51
DP W+ ++ ++ V+ ++ E F E ++ D +F E + + + I
Sbjct: 37 DPLFWLRDDSRKNPEVIAHLKLEQAYFEERTADIKDFSETIFKEYFSHIKETDISAPYRY 96
Query: 52 -GMARITKRGIIVSYSEKDRVTVRWLGG-----EVIVDSKELEKELNDEVLLQGFTTDED 105
G T+ +SY RV + G +VI+D +L + + ++ + D
Sbjct: 97 DGYTYYTREVEGLSYKIHCRVPLGMTPGKSEDEQVILDENKLAEGKSFCMVHEVKPAPPD 156
Query: 106 GKRLAYS--------FSIGGSDEGITRIIDLETGELLEEIKPSVWNIVFLDKGYYFARFY 157
+AYS ++I +D +T +++ G++L S + + D R Y
Sbjct: 157 HNLVAYSVDYVGNEMYTIRFTDNAVTDVVEGTNGQILWGPNASCFFYITKDAA---ERNY 213
Query: 158 RKEKTPDGVNPPAERIFWKDE-------------EGERMVFGEG---LTSGYFMSLRKST 201
+ + G P +E + E +G ++ G G T + + LRK
Sbjct: 214 KIWRHIIG-RPQSEDVCLYTENDLLFSTAMAISGDGNTLIIGSGSFETTESHLLDLRKGN 272
Query: 202 DGKFAMLTLTYGWNKAEIYLGPIDKPEEWKKVYSADVPAEPIDVIDGKLYILTKEGKGL- 260
G E+ +P E Y ++ L ILT + +
Sbjct: 273 -----------GHTTLEMV-----RPRERGVRYDVELHGTET------LLILTNKDNCMN 310
Query: 261 GKVIAVKDSEVEE----IIPEGE--FPLEWAVIVKDKILAGRLVHASHKLEV------YN 308
GKV++ + + I+P E F E V K +L+GR + +
Sbjct: 311 GKVVSATRNTPSDWENVIVPHSEDVFIGEIGVFAKFVVLSGRRGGITRVWAMPVGSDGLF 370
Query: 309 LKGEKISEVEFD------FPGSLYPLDKDDERALLRYTSFTVP---YRIYEFKDELKIVE 359
G + EV FD FP + D E + YTS + P + ++ IV+
Sbjct: 371 RSGAFVQEVSFDEPVFTAFPVFSHMKMYDTETLRVSYTSMSTPTTWFDLHVVNGTRTIVK 430
Query: 360 ERKVEGNFKVEED-----FAISKDGTRVHYFIVKGEK-DEKKAW---VFGYGGFNISLTP 410
R+V GNF + FA + D T++ IV D K ++ YG + + P
Sbjct: 431 VREVLGNFDAKNYTCRRLFATAPDRTKIPLSIVHDVSLDMSKPHPTVLYAYGSYGACVEP 490
Query: 411 RFFPQVIPFLKRGGIFVMANLRGGSEYGEEWHRAGMRE-NKQNVFDDFIAVLEKLKKEGY 469
F + +P+L RG I+V+A++RGG E G W+ G + K+N F DFIA E L + G
Sbjct: 491 EFSVKYLPYLDRGVIYVIAHVRGGGEMGRAWYEVGAKYLTKRNTFSDFIACAEYLIEIGL 550
Query: 470 ----KVAAWGRSNGGLLVSATLVQRPDVMDVALIGYPVIDMLRFH-----KLYIGSVWIP 520
++A GRS GGLL+ A L RPD+ VAL G P +D++ L G W
Sbjct: 551 TTPSQLACEGRSAGGLLIGAVLNMRPDLFRVALAGVPFVDVMTTMCDPSIPLTTGE-W-E 608
Query: 521 EYGNPDDPKDREFLLKYSPYHNVRPQEYPPTLIYTGLHDDRV---HPAHALKFFMKLKEV 577
E+GNP++ K +++ YSP NVR Q+YP +I GLHD RV PA LK
Sbjct: 609 EWGNPNEYKFFDYMNSYSPVDNVRAQDYPHLMIQAGLHDPRVAYWEPAKWASKLRALKTD 668
Query: 578 NAPVYLRVETKSGHMGASPETRA-RELTDLLAFVLLHL 614
+ V L+++ +SGH S R RE++ AFVL HL
Sbjct: 669 SNEVLLKMDLESGHFSPSDRYRYWREMSFPQAFVLKHL 706
>pir||JQ1151 proteinase II (EC 3.4.21.-) - Escherichia coli
>gi|216624|dbj|BAA01750.1| (D10976) protease II
[Escherichia coli]
Length = 707
Score = 157 bits (394), Expect = 3e-37
Identities = 163/662 (24%), Positives = 288/662 (42%), Gaps = 81/662 (12%)
Query: 3 DPYIWM--ENLQDERVLKIVEEENRRFRELVGE---LSDKLFPEVWEYFSQPSIGMARIT 57
D Y W+ + VL +++EN ++ L D++ E+ + Q + I
Sbjct: 21 DNYYWLRDDTRSQPEVLDYLQQENSYGHRVMASQQALQDRILKEIIDRIPQREVSAPYI- 79
Query: 58 KRGI-----------IVSYSEKDRVTVRWLGGEVIVDSKELEKELNDEVLLQG---FTTD 103
K G Y + + W E ++D+ + + + E G T D
Sbjct: 80 KNGYRYRHIYEPGCEYAIYQRQSAFSEEWDEWETLLDANK--RAAHSEFYSMGGMAITPD 137
Query: 104 EDGKRLAYSFSIGGSDEGITRIIDLETG----ELLEEIKPSVWNIVFLDKGYYFARFYRK 159
LA F + GI R +LETG ELL+ ++PS V+ + + F Y
Sbjct: 138 NTIMALAEDF-LSRRQYGI-RFRNLETGNWYPELLDNVEPS---FVWANDSWIF---YYV 189
Query: 160 EKTPDGVNPPAERIFWKDEEG-----ERMVFGEGLTSGYFMSLRKSTDGKFAMLTLTYGW 214
K P + P W+ G +++++ E Y++SL K+T + ++ L
Sbjct: 190 RKHPVTLLPYQ---VWRHAIGTPASQDKLIYEEK-DDTYYVSLHKTTSKHYVVIHLASA- 244
Query: 215 NKAEIYLGPIDKPEEWKKVYSADVPAEP-----IDVIDGKLYILT-KEGK--GLGKVIAV 266
+E+ L + + V+ +P +D + Y+ + + GK GL +
Sbjct: 245 TTSEVRLLDAEMADAEPFVF---LPRRKDHEYSLDHYQHRFYLRSNRHGKNFGLYRTRMR 301
Query: 267 KDSEVEEIIPEGE-FPLEWAVIVKDKILAGRLVHASHKLEVYNLKGEKISEVEFDFPGSL 325
+ + EE+IP E LE + D ++ L N K ++ + FD P +
Sbjct: 302 DEQQWEELIPPRENIMLEGFTLFTDWLVVEERQRGLTSLRQINRKTREVIGIAFDDPAYV 361
Query: 326 ----YPLDKDDERALLRYTSFTVPYRIYEFK---DELKIVEERKVEG----NFKVEEDFA 374
Y + + R Y+S T P ++E E +++++ +V G N++ E +
Sbjct: 362 TWIAYNPEPETARLRYGYSSMTTPDTLFELDMDTGERRVLKQTEVPGFYAANYRSEHLWI 421
Query: 375 ISKDGTRVHYFIVKGEKDEKKAW----VFGYGGFNISLTPRFFPQVIPFLKRGGIFVMAN 430
+++DG V +V K +K V+GYG + S+ F + L RG ++ + +
Sbjct: 422 VARDGVEVPVSLVYHRKHFRKGHNPLLVYGYGSYGASIDADFSFSRLSLLDRGFVYAIVH 481
Query: 431 LRGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGYKVA----AWGRSNGGLLVSAT 486
+RGG E G++W+ G K+N F+D++ + L K GY A G S GG+L+
Sbjct: 482 VRGGGELGQQWYEDGKFLKKKNTFNDYLDACDALLKLGYGSPSLCYAMGGSAGGMLMGVA 541
Query: 487 LVQRPDVMDVALIGYPVIDMLRF---HKLYIGSVWIPEYGNPDDPKDREFLLKYSPYHNV 543
+ QRP++ + P +D++ + + + E+GNP DP+ E++ YSPY NV
Sbjct: 542 INQRPELFHGVIAQVPFVDVVTTMLDESIPLTTGEFEEWGNPQDPQYYEYMKSYSPYDNV 601
Query: 544 RPQEYPPTLIYTGLHDDRVHPAHALKFFMKLKEVNAPVYLRV---ETKSGHMGASPETRA 600
Q YP L+ TGLHD +V K+ KL+E+ +L + + SGH G S ++
Sbjct: 602 TAQAYPHLLVTTGLHDSQVQYWEPAKWVAKLRELKTDDHLLLLCTDMDSGHGGKSGRFKS 661
Query: 601 RE 602
E
Sbjct: 662 YE 663
>sp|P24555|PTRB_ECOLI PROTEASE II (OLIGOPEPTIDASE B) >gi|7428207|pir||E64946
oligopeptidase B (EC 3.4.21.83) - Escherichia coli
>gi|1736485|dbj|BAA15651.1| (D90827) Protease II (EC
3.4.21.83) (Oligopeptidase B). [Escherichia coli]
>gi|1788150|gb|AAC74915.1| (AE000278) protease II
[Escherichia coli K12]
Length = 686
Score = 157 bits (394), Expect = 3e-37
Identities = 163/662 (24%), Positives = 288/662 (42%), Gaps = 81/662 (12%)
Query: 3 DPYIWM--ENLQDERVLKIVEEENRRFRELVGE---LSDKLFPEVWEYFSQPSIGMARIT 57
D Y W+ + VL +++EN ++ L D++ E+ + Q + I
Sbjct: 21 DNYYWLRDDTRSQPEVLDYLQQENSYGHRVMASQQALQDRILKEIIDRIPQREVSAPYI- 79
Query: 58 KRGI-----------IVSYSEKDRVTVRWLGGEVIVDSKELEKELNDEVLLQG---FTTD 103
K G Y + + W E ++D+ + + + E G T D
Sbjct: 80 KNGYRYRHIYEPGCEYAIYQRQSAFSEEWDEWETLLDANK--RAAHSEFYSMGGMAITPD 137
Query: 104 EDGKRLAYSFSIGGSDEGITRIIDLETG----ELLEEIKPSVWNIVFLDKGYYFARFYRK 159
LA F + GI R +LETG ELL+ ++PS V+ + + F Y
Sbjct: 138 NTIMALAEDF-LSRRQYGI-RFRNLETGNWYPELLDNVEPS---FVWANDSWIF---YYV 189
Query: 160 EKTPDGVNPPAERIFWKDEEG-----ERMVFGEGLTSGYFMSLRKSTDGKFAMLTLTYGW 214
K P + P W+ G +++++ E Y++SL K+T + ++ L
Sbjct: 190 RKHPVTLLPYQ---VWRHAIGTPASQDKLIYEEK-DDTYYVSLHKTTSKHYVVIHLASA- 244
Query: 215 NKAEIYLGPIDKPEEWKKVYSADVPAEP-----IDVIDGKLYILT-KEGK--GLGKVIAV 266
+E+ L + + V+ +P +D + Y+ + + GK GL +
Sbjct: 245 TTSEVRLLDAEMADAEPFVF---LPRRKDHEYSLDHYQHRFYLRSNRHGKNFGLYRTRMR 301
Query: 267 KDSEVEEIIPEGE-FPLEWAVIVKDKILAGRLVHASHKLEVYNLKGEKISEVEFDFPGSL 325
+ + EE+IP E LE + D ++ L N K ++ + FD P +
Sbjct: 302 DEQQWEELIPPRENIMLEGFTLFTDWLVVEERQRGLTSLRQINRKTREVIGIAFDDPAYV 361
Query: 326 ----YPLDKDDERALLRYTSFTVPYRIYEFK---DELKIVEERKVEG----NFKVEEDFA 374
Y + + R Y+S T P ++E E +++++ +V G N++ E +
Sbjct: 362 TWIAYNPEPETARLRYGYSSMTTPDTLFELDMDTGERRVLKQTEVPGFYAANYRSEHLWI 421
Query: 375 ISKDGTRVHYFIVKGEKDEKKAW----VFGYGGFNISLTPRFFPQVIPFLKRGGIFVMAN 430
+++DG V +V K +K V+GYG + S+ F + L RG ++ + +
Sbjct: 422 VARDGVEVPVSLVYHRKHFRKGHNPLLVYGYGSYGASIDADFSFSRLSLLDRGFVYAIVH 481
Query: 431 LRGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGYKVA----AWGRSNGGLLVSAT 486
+RGG E G++W+ G K+N F+D++ + L K GY A G S GG+L+
Sbjct: 482 VRGGGELGQQWYEDGKFLKKKNTFNDYLDACDALLKLGYGSPSLCYAMGGSAGGMLMGVA 541
Query: 487 LVQRPDVMDVALIGYPVIDMLRF---HKLYIGSVWIPEYGNPDDPKDREFLLKYSPYHNV 543
+ QRP++ + P +D++ + + + E+GNP DP+ E++ YSPY NV
Sbjct: 542 INQRPELFHGVIAQVPFVDVVTTMLDESIPLTTGEFEEWGNPQDPQYYEYMKSYSPYDNV 601
Query: 544 RPQEYPPTLIYTGLHDDRVHPAHALKFFMKLKEVNAPVYLRV---ETKSGHMGASPETRA 600
Q YP L+ TGLHD +V K+ KL+E+ +L + + SGH G S ++
Sbjct: 602 TAQAYPHLLVTTGLHDSQVQYWEPAKWVAKLRELKTDDHLLLLCTDMDSGHGGKSGRFKS 661
Query: 601 RE 602
E
Sbjct: 662 YE 663
>pir||D83481 probable oligopeptidase PA1304 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9947241|gb|AAG04693.1|AE004560_1
(AE004560) probable oligopeptidase [Pseudomonas
aeruginosa]
Length = 683
Score = 148 bits (371), Expect = 1e-34
Identities = 99/294 (33%), Positives = 147/294 (49%), Gaps = 26/294 (8%)
Query: 328 LDKDDERALLRYTSFTVPYRIYEFK---DELKIVEERKVEGNFKVE-----EDFAISKDG 379
L+ D LRY + P ++ + ++++ VEG F + +A S DG
Sbjct: 367 LEFDSPCVRLRYEALNRPAQVRQLNLADGTQTVLKQTPVEGPFDADAYASRRIWASSGDG 426
Query: 380 TRVHYFIVKGEK--------DEKKAWVFGYGGFNISLTPRFFPQVIPFLKRGGIFVMANL 431
T+V +V ++ +++GYG + SL P F + L+RG +F +A++
Sbjct: 427 TQVPVSLVARKEVLDGIAAGRPAPLYLYGYGAYGHSLDPWFSHARLSLLERGFVFAIAHV 486
Query: 432 RGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGY----KVAAWGRSNGGLLVSATL 487
RGG E GE W+RAG E+KQN FDDFIA E L EGY +A G S GGLL+ A L
Sbjct: 487 RGGGELGEAWYRAGKLEHKQNSFDDFIACAEHLLAEGYCRPEGLAISGGSAGGLLIGAVL 546
Query: 488 VQRPDVMDVALIGYPVIDMLRF---HKLYIGSVWIPEYGNPDDPKDREFLLKYSPYHNVR 544
QRP + A+ P +D+L L + E+GNP +P+ + Y+PY NVR
Sbjct: 547 NQRPQLFGAAIAEVPFVDVLNSMLNPDLPLTVTEYDEWGNPQEPEVHARIAAYAPYENVR 606
Query: 545 PQEYPPTLIYTGLHDDRVHPAHALKFFMKLKEVNAP---VYLRVETKSGHMGAS 595
Q+YP L+ G +D RV A K+ KL+ + L+ + +GH G S
Sbjct: 607 AQDYPHLLVVAGYNDSRVQYWEAAKWVAKLRATRTDANLLLLKTDLGAGHGGMS 660
>gb|AAF43045.1|AF237705_1 (AF237705) oligopeptidase B [Salmonella enterica serovar
Typhimurium]
Length = 683
Score = 148 bits (370), Expect = 2e-34
Identities = 153/656 (23%), Positives = 278/656 (42%), Gaps = 69/656 (10%)
Query: 3 DPYIWM--ENLQDERVLKIVEEENRRFRELVGE---LSDKLFPEVWEYFSQPSIGMARIT 57
D Y W+ + VL + +EN R+++ L D+ E+ + + A
Sbjct: 21 DNYYWLRDDTRSQPEVLDYLHQENEYGRKVMTSQQALQDRTLKEIIDRIPPREVS-APYV 79
Query: 58 KRGI-----------IVSYSEKDRVTVRWLGGEVIVDSKELEKELNDEVLLQGFTTDEDG 106
K G Y + ++ W E ++D+ + ++ L G D
Sbjct: 80 KNGYRYRYIYEPGCEYAIYQRQSALSEEWDVWETLLDANQRAAH-SEFYTLGGLAITPDN 138
Query: 107 KRLAYSFSIGGSDEGITRIIDLETG----ELLEEIKPS-VWNIVFLDKGYYFARFYRKEK 161
+A + + R +LE+G ELL+ + P VW L Y+ R ++K
Sbjct: 139 TIMALAEDYLSRRQYGLRFRNLESGNWYPELLDNVAPEFVWANDSLT--LYYVRKHKKTL 196
Query: 162 TPDGVNPPAERIFWKDEEG-----ERMVFGEGLTSGYFMSLRKSTDGKFAMLTLTYGWNK 216
P V W+ G + +V+ E +++SL K+T + ++ L
Sbjct: 197 LPYQV--------WRHTIGTPSSQDELVYEEK-DDTFYVSLHKTTSQHYVVIHLASATTS 247
Query: 217 AEIYL-GPIDKPEEWKKVYSADVPAEPIDVIDGKLYILT-KEGK--GLGKVIAVKDSEVE 272
+ L + E + + +D K Y+ + + GK GL + ++ E
Sbjct: 248 EVLLLDAELADAEPFSFLPRRKDHEYSLDHYQHKFYLRSNRNGKNFGLYRTRVRNENAWE 307
Query: 273 EIIPEGE-FPLEWAVIVKDKILAGRLVHASHKLEVYNLKGEKISEVEFDFPGSL----YP 327
E+IP E LE + D ++ L N K ++ + FD P + Y
Sbjct: 308 ELIPPREHIMLEGFTLFTDWLVVEERQRGLTSLRQINRKTREVIGIAFDDPAYVTWLAYN 367
Query: 328 LDKDDERALLRYTSFTVPYRIYEFK---DELKIVEERKV----EGNFKVEEDFAISKDGT 380
+ + R Y+S T P ++E E +++++ +V G ++ E + ++DG
Sbjct: 368 PEPETSRLRYGYSSMTTPDTLFELDMDTGERRVLKQTEVPGFDSGCYQSEHLWITARDGV 427
Query: 381 RVHYFIVKGEKDEKKAW----VFGYGGFNISLTPRFFPQVIPFLKRGGIFVMANLRGGSE 436
V +V +K +K V+GYG + S+ F + L RG ++ + ++RGG E
Sbjct: 428 EVPVSLVYHQKYFRKGQNPLLVYGYGSYGSSIDADFSSSRLSLLDRGFVYAIVHVRGGGE 487
Query: 437 YGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGYKVAA----WGRSNGGLLVSATLVQRPD 492
G++W+ G K+N F+D++ + L K GY + G S GG+L+ + +RP+
Sbjct: 488 LGQQWYEDGKFLKKRNTFNDYLDACDALLKLGYGSPSLCYGMGGSAGGMLMGVAINERPE 547
Query: 493 VMDVALIGYPVIDMLRF---HKLYIGSVWIPEYGNPDDPKDREFLLKYSPYHNVRPQEYP 549
+ + P +D+L + + + E+GNP D + +++ YSPY NV+ Q+YP
Sbjct: 548 LFHGVIAQVPFVDVLTTMLDESIPLTTGEFEEWGNPQDIEYYDYMKSYSPYDNVKAQDYP 607
Query: 550 PTLIYTGLHDDRVHPAHALKFFMKLKEVNAP---VYLRVETKSGHMGASPETRARE 602
L+ TGLHD +V K+ KL+E+ + L + SGH G S ++ E
Sbjct: 608 HLLVTTGLHDSQVQYWEPAKWVAKLRELKTDQRLLLLCTDMDSGHGGKSGRFKSYE 663
>pir||B82677 peptidase XF1479 [imported] - Xylella fastidiosa (strain 9a5c)
>gi|9106503|gb|AAF84288.1|AE003977_11 (AE003977)
peptidase [Xylella fastidiosa]
Length = 763
Score = 145 bits (363), Expect = 1e-33
Identities = 101/298 (33%), Positives = 151/298 (49%), Gaps = 22/298 (7%)
Query: 339 YTSFTVPYRIYEFK---DELKIVEERKVEG----NFKVEEDFAISKDGTRVHYFIV--KG 389
YTS T P YEF E + ++++ V G + E + ++DG +V +V KG
Sbjct: 463 YTSLTTPATTYEFNVRTGERRQLKQQPVIGYDPSQYVTERLWVTARDGVKVPVSLVYRKG 522
Query: 390 EKDEKKA--WVFGYGGFNISLTPRFFPQVIPFLKRGGIFVMANLRGGSEYGEEWHRAGMR 447
K + A + + YG + +S P F V+ L RG ++ +A++RGG E G +W+ G
Sbjct: 523 FKKDGTAALYQYAYGSYGLSTDPGFNLPVVSLLDRGVVYAIAHIRGGQEMGRQWYDDGKL 582
Query: 448 ENKQNVFDDFIAVLEKLKKEGY----KVAAWGRSNGGLLVSATLVQRPDVMDVALIGYPV 503
+KQN F+DFI V L +GY +VAA G S GGLL+ Q P V + P
Sbjct: 583 LHKQNTFNDFIDVTRALVAQGYAAKGRVAAAGGSAGGLLMGVVANQAPSDYRVIVAQVPF 642
Query: 504 IDMLRF---HKLYIGSVWIPEYGNPDDPKDREFLLKYSPYHNVRPQEYPPTLIYTGLHDD 560
+D++ + + + E+GNP+ +++L YSPY NV Q YP + TGL D
Sbjct: 643 VDVVTTMLDPSIPLTTNEYDEWGNPEQKVYYDYMLTYSPYDNVVHQAYPALFVGTGLWDS 702
Query: 561 RVHPAHALKFFMKLKEVNA---PVYLRVETKSGHMGASPE-TRARELTDLLAFVLLHL 614
+V K+ KL++ N P+ RV +GH G S R +EL + AFVL HL
Sbjct: 703 QVQYWEPAKWVAKLRDENTGALPIVFRVNMDAGHGGKSGRFRRYQELAESYAFVLHHL 760
>dbj|BAA20518.1| (AB004795) dipeptidyl aminopeptidase [Pseudomonas sp.]
Length = 723
Score = 142 bits (354), Expect = 1e-32
Identities = 163/681 (23%), Positives = 288/681 (41%), Gaps = 85/681 (12%)
Query: 3 DPYIWM--ENLQDERVLKIVEEENRRFRELVGELS---DKLFPEV--------------- 42
D Y W+ + +++ +L + EN ++ L DKL+ EV
Sbjct: 48 DEYYWLRDDKRENKEMLAYLNAENAYTDAVMAPLKPLEDKLYDEVVARIKQDDASVPYRE 107
Query: 43 --WEYFSQPSIGM------ARITKRGIIVSYSEKDRVTVRWLGGEVIVDSKELEKELNDE 94
W Y+++ G R G+ + + G +V++D L D
Sbjct: 108 RGWWYYARFVTGKDYPVHARRKDGPGVDAVSIQAANAAGDFAGEQVLLDVNALGAG-KDY 166
Query: 95 VLLQGFTTDEDGKRLAYSFSIGGSDEGITRIIDLETGELLEE-IKPSVWNIVFLDKGYYF 153
+ + +D + LAY+ G + R +L+TGELL + + + N+V+ D G
Sbjct: 167 YNVGDYEVSQDNRLLAYADDTNGRRQYTIRFKNLDTGELLPDTVTNAEPNLVWSDDG--- 223
Query: 154 ARFYRKEKTPDGVNPPAER--IFWKDEEGERMVFGEGLTSGYFMSLRKSTDGKFAMLTLT 211
+ +K P+ + + + + +V+ E S ++M + +S D KF +++
Sbjct: 224 RTLFYVDKDPETLLSKRVKAHVLGTPASQDALVYEEEDDS-FYMGIGRSRDDKFICISVE 282
Query: 212 YGWNKAEIYLGPIDKPEEWKKVYSADVPAE-PIDVIDGKLYILTK-EGKGLGKVIAVKDS 269
+E+ P P + + + E D + + I T +G K++
Sbjct: 283 -STVSSEMRCTPAASPGVFTVLAPRERDVEYQADHLGDRWVIRTNADGATNFKIVTAPTD 341
Query: 270 EV------------EEIIPEGEFPLEWAVIVKDKILAGRLVHASHKLEVYNLKGE----K 313
+++ EG + +V ++ +A L V G K
Sbjct: 342 STSRKDWKDWVAHRDDVFVEGFELFDGFSVVAER------ANALESLRVIKADGSSDYVK 395
Query: 314 ISEVEFDFPGSLYPLDKDDERALLRYTSFTVPYRIYEFKD---ELKIVEERKVEG----N 366
E + S P + + YTS T P YE E + ++++ V G
Sbjct: 396 ADESAYSMGLSANP-ETGTDWLRYSYTSMTTPATTYEINTKTGERRQLKQQPVPGYDASK 454
Query: 367 FKVEEDFAISKDG-TRVHYFIVKGE---KDEKKAWV-FGYGGFNISLTPRFFPQVIPFLK 421
+ E +A ++DG T++ +V + +D K + + YG + S+ P F + L
Sbjct: 455 YVTERVWAPARDGKTKIPVTLVYRKDVARDGKAPMLQYAYGSYGASMDPNFSITNVSLLD 514
Query: 422 RGGIFVMANLRGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGY----KVAAWGRS 477
RG ++ +A++RGG E G W+ G NK N F DFI V + L KEGY +VAA G S
Sbjct: 515 RGVVYALAHIRGGQEMGRAWYDDGKLYNKINTFTDFIDVTDYLVKEGYAAKDRVAAMGGS 574
Query: 478 NGGLLVSATLVQRPDVMDVALIGYPVIDMLRF---HKLYIGSVWIPEYGNPDDPKDREFL 534
GGLL+ A P+ V L P +D++ + + + E+GNP++ +++
Sbjct: 575 AGGLLMGAVSNMAPEKYKVILTLVPFVDVVTTMLDPTIPLTTNEYDEWGNPEEKGYYDYI 634
Query: 535 LKYSPYHNVRPQEYPPTLIYTGLHDDRVHPAHALKFFMKLKEVN---APVYLRVETKSGH 591
L YSPY N++ + YP + TGL D +V K+ +L+++N PV R ++GH
Sbjct: 635 LTYSPYDNLQAKAYPAMFVGTGLWDSQVQYWEPAKYVARLRDLNTGKGPVVFRTNMEAGH 694
Query: 592 MGASPETRA-RELTDLLAFVL 611
G S R RE ++ AF+L
Sbjct: 695 GGKSGRFRQYRERAEMFAFML 715
>gb|AAF17627.1|AC009978_3 (AC009978) T23E18.7 [Arabidopsis thaliana]
Length = 650
Score = 141 bits (353), Expect = 2e-32
Identities = 156/570 (27%), Positives = 233/570 (40%), Gaps = 105/570 (18%)
Query: 3 DPYIWMENLQDERVLKIVE-------------EENRRFRELVGELSD-----KLFPEVWE 44
DPY W+E+ E V + V+ E + R+ + +L D F + +
Sbjct: 97 DPYRWLEDPDAEEVKEFVQSQVKLTDSVLEKCETKEKLRQNITKLIDHPRYDSPFRQGDK 156
Query: 45 YFSQPSIGMARITKRGIIVSYSEKDRVTVRWLGGEVIVDSKELEKELNDEVLLQGFTTDE 104
YF + G+ + ++ D EV++D L + V L F+ E
Sbjct: 157 YFYFHNTGLQA---QSVLYMQDNLDAEP------EVLLDPNTLSDD--GTVALNTFSVSE 205
Query: 105 DGKRLAYSFSIGGSDEGITRIIDLETGEL----LEEIKPSVWNIVFLDKGYYFARFYRKE 160
D K LAY S GSD +++ +E ++ L +K + KG+++ R+ +
Sbjct: 206 DAKYLAYGLSSSGSDWVTIKLMKIEDKKVEPDTLSWVKFTGITWTHDSKGFFYGRYPAPK 265
Query: 161 KTPD--------------------GVNPPAERIFWKDEEGERMVFGEGLTSG---YFMSL 197
+ D G + + + W+D E + +FG +T MS+
Sbjct: 266 EGEDIDAGTETNSNLYHELYYHFIGTDQSQDILCWRDNENPKYMFGAEVTDDGKYLIMSI 325
Query: 198 RKSTD--GKFAMLTLTYGWNKAEIYLGPIDKPEEWKKVYSADVPAEPIDVIDGKLYILTK 255
+S D K +T E + G K V + D I + LT
Sbjct: 326 GESCDPVNKLYYCDMTSLSGGLESFRGSSSFLPFIKLVDTFDAQYSVISNDETLFTFLTN 385
Query: 256 EGKGLGKVIAVKDSEVEEIIPEGEFPLEWAVIV----KDKILAGRLVHASHKLEVYNLKG 311
+ K++ V E P W +V KD + + V+ +H + Y
Sbjct: 386 KDAPKYKLVRVDLKE----------PNSWTDVVEEHEKDVLASACAVNGNHLVACYMSDV 435
Query: 312 EKISEVEFDFPGSLY---PLD----------KDDERALLRYTSFTVPYRIYEF-----KD 353
+ I ++ GSL PLD + D +TSF P IY+
Sbjct: 436 KHILQIRDLKSGSLLHQLPLDIGSVSDVSARRKDNTFFFSFTSFLTPGVIYKCDLANESP 495
Query: 354 ELKIVEERKVEG----NFKVEEDFAISKDGTRVHYFIVKGEKDEK-----KAWVFGYGGF 404
E+K+ E V G F+ + F SKDGT++ FIV +KD K ++ YGGF
Sbjct: 496 EVKVFREVTVPGFDREAFQAIQVFYPSKDGTKIPMFIV-AKKDIKLDGSHPCLLYAYGGF 554
Query: 405 NISLTPRFFPQVIPFLKR-GGIFVMANLRGGSEYGEEWHRAGMRENKQNVFDDFIAVLEK 463
NIS+TP F I K G +F AN+RGG EYGEEWH+AG KQN FDDFI+ E
Sbjct: 555 NISITPSFSASRIVLSKHLGVVFCFANIRGGGEYGEEWHKAGSLAKKQNCFDDFISGAEY 614
Query: 464 LKKEGY----KVAAWGRSNGGLLVSATLVQ 489
L GY K+ G SNGGLLV A + Q
Sbjct: 615 LVSAGYTQPSKLCIEGGSNGGLLVGACINQ 644
>emb|CAB08412.1| (Z95151) PtrB [Mycobacterium leprae]
Length = 724
Score = 136 bits (338), Expect = 1e-30
Identities = 165/677 (24%), Positives = 276/677 (40%), Gaps = 88/677 (12%)
Query: 3 DPYIWMENLQDERVLKIVEEENRRFRELVGELS---DKLFPEV----------------- 42
DPY W+ + + V+ ++ EN ++ L K+F E+
Sbjct: 30 DPYEWLRDNNNPEVVAYLDAENDYVNQMTAHLEPLQQKIFNEIKARTKENDLSVPTRQAN 89
Query: 43 WEYFSQPSIGMA-RITKRGIIVSYSEKDRVTV---RWLGGEVIVDSKELEKELNDEVLLQ 98
W Y+S+ G R+ R + S + + + GE ++ E E + L
Sbjct: 90 WWYYSRTFEGKQYRVQCRCPVASPDDWTPPALYENTEISGEQVLLDSNAEAEGHAFFALG 149
Query: 99 GFTTDEDGKRLAYSFSIGGSDEGITRIIDLETGELLEEIKPSVWNIVFLDKGYYFARFYR 158
F D LAYS G + R DL TGE + IV + G +A R
Sbjct: 150 TFMVSLDSNLLAYSVDFVGDERYTLRFKDLRTGERYPD------EIVGIGAGATWAADNR 203
Query: 159 --------KEKTPD-------GVNPPAERIFWKDEEGERMVFGEGLTSGY-FMSLRKSTD 202
+ + PD G P+E+++ + +E + G + Y F++ +
Sbjct: 204 TVYYLTLDESRRPDTVWRCRLGSGQPSEQVYHEADERFWLAVGLSRSEAYIFIAAGSAIT 263
Query: 203 GKFAMLTLTYGWNKAEIYLGPIDKPEEWKKVYSADVPAEPIDVIDG--KLYILTKEGKGL 260
++ T + + L D E YS V P ++ G + IL +G
Sbjct: 264 SEWRYADSTNPDAQFTVVLPRRDGIE-----YS--VEHAPSGLVGGQDRFLILHNDGAVN 316
Query: 261 GKVIAVKDSEVEE---IIPE-GEFPLEWAVIVKDKILAGRLVHASHKLEVYNLKGE---- 312
++ S E+ +IP + L+ A ++ A +++++ + +
Sbjct: 317 FTLVESPVSNPEQQRTLIPHRDDVRLDSADAFAGYLVVSYRREALPRVQLWPIDPDGSYG 376
Query: 313 KISEVEFDFPGSLYPLDKDDE----RALLRYTSFTVPYRIYEFK---DELKIVEERKVEG 365
+ E+ F+ L+ + + +R SF P R+Y+ E ++ E+ V G
Sbjct: 377 EPEEISFESELMWVSLEANSNWVSPKLRIRAGSFVTPVRVYDVDLATGERTLLREQPVLG 436
Query: 366 NFKVEE-----DFAISKDGTRVHYFIVKGE--KDEKKAWVFGYGGFNISLTPRFFPQVIP 418
+K E+ ++A + DGT + IV + A ++GYG + I + P F +
Sbjct: 437 GYKHEDYVERREWAQADDGTWIPVSIVHRAAIRFPAPAVLYGYGAYEICVDPSFSIPRLS 496
Query: 419 FLKRGGIFVMANLRGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEG----YKVAAW 474
L RG +FV+A++RGG E G W+ G K+N F DFI+V + L G ++ A
Sbjct: 497 LLDRGMMFVIAHVRGGGEMGRLWYEHGKLLEKKNTFTDFISVAKHLVDSGQTRSQELVAL 556
Query: 475 GRSNGGLLVSATLVQRPDVMDVALIGYPVIDMLRF---HKLYIGSVWIPEYGNP-DDPKD 530
G S GGLL+ PD+ L P +D L L + E+GNP D
Sbjct: 557 GGSAGGLLMGVVANIAPDLFTGILAQVPFVDPLTTMLDPSLPLTVTEWDEWGNPLIDSDF 616
Query: 531 REFLLKYSPYHNVRPQEYPPTLIYTGLHDDRVHPAHALKFFMKLKEVNA---PVYLRVET 587
++ YSPY NV ++YP L T LHD RVH K+ L+ + PV L+ +
Sbjct: 617 YSYIKSYSPYENVEAKQYPAILAMTSLHDTRVHYVEPAKWIAALRHTKSDGNPVLLKTQM 676
Query: 588 KSGHMGASPETRARELT 604
+GH G S +A + T
Sbjct: 677 AAGHAGISGRYKAWQET 693
>pir||D71683 proteinase II (ptrB) RP281 - Rickettsia prowazekii
>gi|3860842|emb|CAA14742.1| (AJ235271) PROTEASE II
(ptrB) [Rickettsia prowazekii]
Length = 684
Score = 135 bits (337), Expect = 1e-30
Identities = 89/317 (28%), Positives = 157/317 (49%), Gaps = 25/317 (7%)
Query: 318 EFDFPGSLYPLDKDDERALLRYTSFTVPYRIYEF---KDELKIVEERKVEGNF-----KV 369
+ F + + + +++ + Y+S P Y + K++L I++++++ F KV
Sbjct: 361 DVSFQANSFSTNFEEDNIRIDYSSLARPNTTYSYDFDKNKLTILKDQEIPSGFNPEEYKV 420
Query: 370 EEDFAISKDGTRVHYFIVKGEKDEKK-----AWVFGYGGFNISLTPRFFPQVIPFLKRGG 424
E FA +G +V + + KK ++ GYG + I++ F + RG
Sbjct: 421 ERIFA-DNEGVKVPITLFYKKSLFKKDGSNPLYLIGYGAYGITMPVNFRNIAVTLTNRGF 479
Query: 425 IFVMANLRGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGY----KVAAWGRSNGG 480
I+ +A++RGG + G +W+ A K+ F+DFIA L KE Y + G S GG
Sbjct: 480 IYAIAHIRGGDDLGHDWYEAAKFLTKKRTFEDFIACSRTLIKEKYTNNNNIVIAGGSAGG 539
Query: 481 LLVSATLVQRPDVMDVALIGYPVIDMLRF---HKLYIGSVWIPEYGNPDDPKDREFLLKY 537
+L+ L ++P++ A+ P +D+L L + + E+GNP + + +++ Y
Sbjct: 540 MLIGYVLNEKPEIYRAAIAHVPFVDVLNTMLDENLPLTLLEYNEWGNPKEQEYFDYIKSY 599
Query: 538 SPYHNVRPQEYPPTLIYTGLHDDRVHPAHALKFFMKLKEV---NAPVYLRVETKSGHMGA 594
SPY NV+ Q YP I G+ D RV K+ KL+E+ N P+ L++ +GH GA
Sbjct: 600 SPYDNVKTQNYPALFIRCGISDPRVGYWEPAKWVAKLRELKTDNNPLLLKINMDTGHQGA 659
Query: 595 SPE-TRARELTDLLAFV 610
+ +E+TD L F+
Sbjct: 660 AGRFDYLQEITDELVFI 676
>gb|AAD50051.1|AC007980_16 (AC007980) Similar to oligopeptidases [Arabidopsis thaliana]
Length = 710
Score = 133 bits (331), Expect = 6e-30
Identities = 89/281 (31%), Positives = 136/281 (47%), Gaps = 23/281 (8%)
Query: 338 RYTSFTVPYRIYEFKDELKIVEERKVE--------GNFKVEEDFAISKDGTRVHYFIVKG 389
+Y S P +Y++ + +K++ N+ E + + DGT++ IV
Sbjct: 403 KYCSMKTPPSVYDYDMDSGTSVVKKIDTVLGGFDASNYVTERKWVAASDGTQIPMSIVYN 462
Query: 390 EKDEK-----KAWVFGYGGFNISLTPRFFPQVIPFLKRGGIFVMANLRGGSEYGEEWHRA 444
+K K ++GYG + IS+ P F + L RG FV+A++RGG E G +W+
Sbjct: 463 KKLAKLDGSDPLLLYGYGSYEISVDPYFKASRLSLLDRGFTFVIAHVRGGGEMGRQWYEN 522
Query: 445 GMRENKQNVFDDFIAVLEKLKKEGY----KVAAWGRSNGGLLVSATLVQRPDVMDVALIG 500
G K+N F DFIA E+L + Y K+ GRS GGLL+ A + RPD+ V + G
Sbjct: 523 GKLLKKKNTFTDFIACAERLIELKYCSKEKLCMEGRSAGGLLMGAVVNMRPDLFKVVIAG 582
Query: 501 YPVIDMLRFHKLYIGSVWIPEYGNPDDPKDREF---LLKYSPYHNVRPQEYPPTLIYTGL 557
P +D+L + E+ DP+ EF + YSP NV Q YP L+ GL
Sbjct: 583 VPFVDVLTTMLDPTIPLTTSEWEEWGDPRKEEFYFYMKSYSPVDNVTAQNYPNMLVTAGL 642
Query: 558 HDDRVHPAHALKFFMKLKEV---NAPVYLRVETKSGHMGAS 595
+D RV + K+ KL+E+ N + + E +GH S
Sbjct: 643 NDPRVMYSEPGKWVAKLREMKTDNNVLLFKCELGAGHFSKS 683
>pir||A70709 probable ptrBa protein - Mycobacterium tuberculosis (strain H37RV)
>gi|1550660|emb|CAB02372.1| (Z80226) ptrBa
[Mycobacterium tuberculosis]
Length = 552
Score = 130 bits (324), Expect = 4e-29
Identities = 94/276 (34%), Positives = 133/276 (48%), Gaps = 21/276 (7%)
Query: 341 SFTVPYRIYEFK---DELKIVEERKVEGNFKVEE-----DFAISKDGTRVHYFIVKGEKD 392
SF P RIY+ E +++E+ V G ++ E+ D+A DGTR+ IV
Sbjct: 238 SFVTPVRIYDIDLVTGERTLLKEQPVLGGYRREDYVERRDWAYGDDGTRIPVSIVHRADI 297
Query: 393 E--KKAWVFGYGGFNISLTPRFFPQVIPFLKRGGIFVMANLRGGSEYGEEWHRAGMRENK 450
E A ++GYG + I PRF + L RG +FV+A++RGG E G W+ G +K
Sbjct: 298 EFPAPALIYGYGAYEICEDPRFSIARLSLLDRGMVFVVAHVRGGGEMGRLWYENGKLLDK 357
Query: 451 QNVFDDFIAVLEKLKKEG----YKVAAWGRSNGGLLVSATLVQRPDVMDVALIGYPVIDM 506
+N F DFIAV L G ++ A G S GGLL+ A PD+ L P +D
Sbjct: 358 KNTFTDFIAVARHLVDTGLTSQQQLVALGGSAGGLLMGAVANMAPDLFAGILAQVPFVDP 417
Query: 507 LRF---HKLYIGSVWIPEYGNP-DDPKDREFLLKYSPYHNVRPQEYPPTLIYTGLHDDRV 562
L L + E+GNP +D ++ YSPY NV Q+YP L T L+D RV
Sbjct: 418 LTTILDPSLPLTVTEWDEWGNPLNDSDVYAYVKSYSPYENVTAQKYPAILAMTSLNDTRV 477
Query: 563 HPAHALKFFMKLKEVNA---PVYLRVETKSGHMGAS 595
+ K+ L+ V L+ + +GH G S
Sbjct: 478 YYVEPAKWVAALRHAKTDGNSVLLKTQMHAGHGGIS 513
>pir||E82506 proteinase II VCA0063 [imported] - Vibrio cholerae (group O1 strain
N16961) >gi|9657446|gb|AAF95977.1| (AE004349) protease
II [Vibrio cholerae]
Length = 665
Score = 130 bits (324), Expect = 4e-29
Identities = 72/224 (32%), Positives = 120/224 (53%), Gaps = 9/224 (4%)
Query: 398 VFGYGGFNISLTPRFFPQVIPFLKRGGIFVMANLRGGSEYGEEWHRAGMRENKQNVFDDF 457
++GYG + +++ P F PQ++ L RG I+ +A++RGG GE WH+AG NKQN DDF
Sbjct: 434 LYGYGAYGVTMKPYFMPQIVSLLDRGMIYAIAHVRGGGYLGEAWHQAGAGLNKQNGIDDF 493
Query: 458 IAVLEKLK--KEGYK-VAAWGRSNGGLLVSATLVQRPDVMDVALIGYPVIDMLRF---HK 511
+A L ++G + + G S GG LV+A L Q+P++ A++ P +D+L
Sbjct: 494 LAAARYLTHFQQGERAIYTIGGSAGGTLVAAALNQQPNLFAGAVLQVPFVDVLASMSDTS 553
Query: 512 LYIGSVWIPEYGNPDDPKDREFLLKYSPYHNVRPQEYPPTLIYTGLHDDRVHPAHALKFF 571
+ + E+GNP P+ R+ + Y P N+R YPPTL+ G D+RV ++
Sbjct: 554 QALTAQQYQEWGNPQQPEQRQVMQAYDPLSNLRAAPYPPTLVNVGWWDNRVPYWEGARYL 613
Query: 572 MKLKEVN---APVYLRVETKSGHMGASPETRARELTDLLAFVLL 612
+L +V+ P L + ++GH + ++ + F+ L
Sbjct: 614 ARLSDVSQGAGPYLLSTDFQAGHASDRRQALEKQAREYAFFLTL 657
>sp|P55656|Y4SO_RHISN PROBABLE PEPTIDASE Y4SO >gi|2182630|gb|AAB91854.1| (AE000097) Y4sO
[Rhizobium sp. NGR234]
Length = 705
Score = 104 bits (257), Expect = 3e-21
Identities = 152/660 (23%), Positives = 253/660 (38%), Gaps = 73/660 (11%)
Query: 3 DPYIWMENLQDERVLKIVEEENRRFREL---VGELSDKLFPEVWEYFSQPSIGMARITKR 59
D Y W+ + +D VL +E EN E+ V EL L E+ + S
Sbjct: 27 DSYGWLRDREDPDVLAYLEAENHYADEVTSYVAELKADLIAEIEKRDSCDGAPPPFQVGF 86
Query: 60 GIIVSYSEKDRVTVRWLGGEVIVDSKELEKELND----EVL--LQGFTTDEDGKRLAYSF 113
S+ + W V +EL + N EV L +DG+ +A+SF
Sbjct: 87 FFYFQKSQSGLLHSAWWRRPVTGGPEELVFDPNTLPGAEVFYSLGALEPSDDGRYIAFSF 146
Query: 114 SIGGSDEGITRIIDLETGELLEEIKPSVWNIVFL--DKGYYFARFYRKEKTPDGVNPPAE 171
+ G++ R+ D+ G + +V+ ++ +F R + D V
Sbjct: 147 DLIGNERYELRVRDMTNGREIWRDPSRAGRLVWAADNRTLFFTRERADRRQHDRV----- 201
Query: 172 RIFWKDEEGERMVFGEGLTSGYFMSLRKSTDGKFAMLTLTYGWNK--------AEIYLGP 223
+ E G V E + + +R+S G + + + + AE++ P
Sbjct: 202 -VRLDVETGRSEVVFEEVNERLALVVRRSGSGAYLFIDVIITSDMSSRIQRAAAEVWCLP 260
Query: 224 IDKPEE-WKKVYSADVPAEPIDVIDGK--LYILTKEGKGLGKVIAVKD----SEVEEIIP 276
++P + W+++ + ++ E G L+ + G L V D S +E++P
Sbjct: 261 AERPTDMWRRILARELGHEIYAEHWGNEFLFRVNDTGPNLRLVRTAIDDTSPSRWQEVVP 320
Query: 277 E-GEFPLEWAVIVKDKILAGRLVHASHKLEVYNLKGE---KISEVEFDFP-------GSL 325
LE ++++ ++ +L ++ G I VE G
Sbjct: 321 HRAGITLEEIHVLEEHVIVLEREGIQPRLVAHHRNGRVGPSIVPVEHSCTVTVGLSAGGS 380
Query: 326 YPLDKDDERA---LLRYTSFTVPYRIYE---FKDELKIVEERKVEGN----FKVEEDFAI 375
Y + R + SF P + D+ K++ V G ++ A
Sbjct: 381 YSCARHPYRVSALTYKICSFVTPDIFIQHDLLTDKSKVLYRTLVSGFEPELYEARVVMAK 440
Query: 376 SKDGTRVHYFIV--KGEKDEKKAWVFGYGGFNISLTPRFF------PQVIPFLKRGGIFV 427
++DG V IV + ++ + YG + P FF + L RG F
Sbjct: 441 AEDGVEVPISIVARRDRGEDGPVLLNVYGCYGAQSLPAFFGWPSSMTARLSLLDRGVAFG 500
Query: 428 MANLRGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGYK----VAAWGRSNGGLLV 483
+ ++RGG E G WH A R+ K+ D IA E L + + + GRS GG V
Sbjct: 501 IVHVRGGGELGRAWHEAATRDQKRLTHTDLIAAAECLVEHRFASRDGIVIEGRSAGGGTV 560
Query: 484 SATLVQRPDVMDVALIGYPVIDMLRFH---KLYIGSVWIPEYGNPDDPKDREFLLKYSPY 540
A V RPD+ L P+ D++ L EYG+P D ++L Y PY
Sbjct: 561 LAAAVLRPDLFRAVLAEVPLADIIDTELDFTLPYALRETAEYGDPHLANDYQYLRSYDPY 620
Query: 541 HNVRP-QEYPPTLIYTGLHDDRV---HPA-HALKFFMKLKEVNAPVYLRVETKSGHMGAS 595
+N+ P + YPPT I LHD +V PA + + K + + + R GHMG S
Sbjct: 621 YNLTPDRRYPPTYIDAALHDSQVLYYQPARYVAQRRSKAVDRDPDLIFRTRMIGGHMGVS 680
>gb|AAF07357.1|AC011665_16 (AC011665) putative protease [Arabidopsis thaliana]
Length = 798
Score = 103 bits (255), Expect = 5e-21
Identities = 70/235 (29%), Positives = 106/235 (44%), Gaps = 17/235 (7%)
Query: 376 SKDGTRVHYFIVKG----EKDEKKAWVFGYGGFNISLTPRFFPQVIPFLKRGGIFVMANL 431
S DG V I+ +K E + GYG + L + + L RG + A++
Sbjct: 536 SHDGVEVPLTILYSREAWKKSESPGMLIGYGAYGEVLDKSWCTNRLSMLDRGWVIAFADV 595
Query: 432 RGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGY----KVAAWGRSNGGLLVSATL 487
RGG WH++G R KQN DFI + L ++GY +AA G S G +L +A +
Sbjct: 596 RGGGSGEFSWHKSGTRSLKQNSIQDFIYSAKYLVEKGYVHRHHLAAVGYSAGAILPAAAM 655
Query: 488 VQRPDVMDVALIGYPVIDMLRF---HKLYIGSVWIPEYGNPDDPKDREFLLKYSPYHNVR 544
P + ++ P +D+L L + + E+GNPD+ D +L YSPY +R
Sbjct: 656 NMHPSLFQAVILKVPFVDVLNTLSDPNLPLTLLDHEEFGNPDNQTDFGSILSYSPYDKIR 715
Query: 545 PQE-YPPTLIYTGLHDDRVHPAHALKFFMKLK-----EVNAPVYLRVETKSGHMG 593
YP L+ T HD RV K+ K++ + + V L+ GH G
Sbjct: 716 KDVCYPSMLVTTSFHDSRVGVWEGAKWVAKIRDSTCHDCSRAVILKTNMNGGHFG 770
>dbj|BAB08935.1| (AB026640) protease-like [Arabidopsis thaliana]
Length = 792
Score = 87.4 bits (213), Expect = 4e-16
Identities = 59/212 (27%), Positives = 102/212 (47%), Gaps = 11/212 (5%)
Query: 376 SKDGTRVHYFIV----KGEKDEKKAWVFGYGGFNISLTPRFFPQVIPFLKRGGIFVMANL 431
S DG V IV + E+++K + +G + L R+ ++ L RG + A++
Sbjct: 538 SHDGAMVPLSIVYSRAQKEENQKPGLLHVHGAYGEMLDKRWRSELKSLLDRGWVLAYADV 597
Query: 432 RGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKK----EGYKVAAWGRSNGGLLVSATL 487
RGG G++WH+ G K N D+I + L + E K+A WG S GGL+V++ +
Sbjct: 598 RGGGGKGKKWHQDGRGAKKLNSIKDYIQCAKYLVENNIVEENKLAGWGYSAGGLVVASAI 657
Query: 488 VQRPDVMDVALIGYPVID---MLRFHKLYIGSVWIPEYGNPDDPKDREFLLKYSPYHNVR 544
PD+ A++ P +D L + L + + E+G P D D + +YSPY N+
Sbjct: 658 NHCPDLFQAAVLKVPFLDPTHTLIYPILPLTAEDYEEFGYPGDINDFHAIREYSPYDNIP 717
Query: 545 PQEYPPTLIYTGLHDDRVHPAHALKFFMKLKE 576
P ++ T + R A K+ ++++
Sbjct: 718 KDVLYPAVLVTSSFNTRFGVWEAAKWVARVRD 749
>dbj|BAA23709.1| (AB007896) KIAA0436 [Homo sapiens]
Length = 689
Score = 86.2 bits (210), Expect = 1e-15
Identities = 125/538 (23%), Positives = 207/538 (38%), Gaps = 52/538 (9%)
Query: 79 EVIVDSKELEKELNDEVLLQGFTTDEDGKRLAYSFSIGGSDEGITRIIDLETGELLEEIK 138
EV+ + +EL+ D+ + D K +A S+ II L ++E
Sbjct: 105 EVLFNLEELKL---DQPFIDCIRVAPDEKYVAAKIRTEDSEASTCVIIKLSDQPVMEASF 161
Query: 139 PSVWNIVFL----DKGYYFARFYRKEKTPDGVNPPAERIFWKDEEGERMVFGEGLTSGYF 194
P+V + ++ D+ F F R + D F ++ ER F YF
Sbjct: 162 PNVSSFEWVKDEEDEDVLFYTFQRNLRCHDVYRAT----FGDNKRNER--FYTEKDPSYF 215
Query: 195 MSLRKSTDGKFAMLTLTYGWNKAEIYLGPIDKPEEW-------KKVYSADVPAEPIDVID 247
+ L + D +F + + NK + ID W K+++ ++ D
Sbjct: 216 VFLYLTKDSRFLTINIM---NKTTSEVWLIDGLSPWDPPVLIQKRIHGV---LYYVEHRD 269
Query: 248 GKLYILTKEGKGLGKVIAVKDSEVEEIIPEGEF---PLEWAVIVKDKILAGRLVHASHK- 303
+LYILT G+ + ++ I+ F VI D ++ H
Sbjct: 270 DELYILTNVGEPTEFKLMRTAADTPAIMNWDLFFTMKRNTKVIDLDMFKDHCVLFLKHSN 329
Query: 304 ---LEVYNLKGEKISEVEFD--FPGSLYPLDKDDERALLRYTSFTVPYRIYEFK-DELKI 357
+ V L + + ++ G + + D + + S P + Y +K E K+
Sbjct: 330 LLYVNVIGLADDSVRSLKLPPWACGFIMDTNSDPKNCPFQLCSPIRPPKYYTYKFAEGKL 389
Query: 358 VEERKVEGNF----KVEEDFAISKDGTRVHYFIVKGEKDE----KKAWVFGYGGFNISLT 409
EE E +V A SKDG V + E K V YG + + L
Sbjct: 390 FEETGHEDPITKTSRVLRLEAKSKDGKLVPMTVFHKTDSEDLQKKPLLVHVYGAYGMDLK 449
Query: 410 PRFFPQVIPFLKRGGIFVMANLRGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGY 469
F P+ + G I ++RGG E G +WH G K N D A ++ L +G+
Sbjct: 450 MNFRPERRVLVDDGWILAYCHVRGGGELGLQWHADGRLTKKLNGLADLEACIKTLHGQGF 509
Query: 470 K----VAAWGRSNGGLLVSATLVQRPDVMDVALIGYPVIDMLRF---HKLYIGSVWIPEY 522
S GG+L A P+++ + P +D+L L + + E+
Sbjct: 510 SQPSLTTLTAFSAGGVLAGALCNSNPELVRAVTLEAPFLDVLNTMMDTTLPLTLEELEEW 569
Query: 523 GNP-DDPKDREFLLKYSPYHNVRPQEYPPTLIYTGLHDDRVHPAHALKFFMKLKEVNA 579
GNP D K + ++ +Y PY N++PQ YP I +D+RV + + KLKE A
Sbjct: 570 GNPSSDEKHKNYIKRYCPYQNIKPQHYPSIHITAYENDERVPLKGIVSYTEKLKEAIA 627
>sp|P55627|Y4QF_RHISN PROBABLE PEPTIDASE Y4QF >gi|2182591|gb|AAB91830.1| (AE000092) Y4qF
[Rhizobium sp. NGR234]
Length = 754
Score = 81.1 bits (197), Expect = 3e-14
Identities = 91/399 (22%), Positives = 161/399 (39%), Gaps = 50/399 (12%)
Query: 223 PID--KPEEWKKV--YSADVPAEPIDVIDGKLYILTKEGKGLGKVIAVKDSEVEEIIPEG 278
PID P W++V + A V + I V++ L +L +EG + + V +I
Sbjct: 337 PIDDPSPSRWEEVVPHRAGVTIDEIHVLEQHLVLLEREGLRPRLISRNRSGRVGAVI--- 393
Query: 279 EFPLEWAVIVKDKILAGRLVHASHKLEVYNLKGEKI--SEVEFDFPGSLYPLDKDDERAL 336
P E + ++ + AG A+ + + K+ S F P + D ++R++
Sbjct: 394 -VPDEPSCTIRVGLSAGGCYSAAR----HPFRSSKLTYSVSSFVTPDTFIEHDFANDRSV 448
Query: 337 LRYTSFTVPYRIYEFKDELKIVEERKVEGNFKVEEDFAISKDGTRVHYFIV--KGEKDEK 394
+ + Y ++ + + E ++DG +V +V +
Sbjct: 449 VLCEARVPGYDATQYLATVVMAE----------------AEDGVQVPISLVARRDRTSPG 492
Query: 395 KAWVFGYGGFNISLTPRFFPQV------IPFLKRGGIFVMANLRGGSEYGEEWHRAGMRE 448
+ YG + I P F + L R F + ++RGG E G WH A R+
Sbjct: 493 PVLLSVYGCYGIPRLPSFLAWPSSMTARLSLLDREVAFGIVHVRGGGELGRPWHDAATRD 552
Query: 449 NKQNVFDDFIAVLEKLKKEGYK----VAAWGRSNGGLLVSATLVQRPDVMDVALIGYPVI 504
K+ D I+ E L + G+ V G+S GG V AT V RP++ + P+
Sbjct: 553 QKRITHTDLISATEGLIERGFATRDGVVIEGKSGGGGTVLATAVFRPNLFRAVVAEVPLA 612
Query: 505 DMLRFH---KLYIGSVWIPEYGNPDDPKDREFLLKYSPYHNVRPQ-EYPPTLIYTGLHDD 560
D++ + EYG+P D + +L Y PY+N+ P+ PPT + L D
Sbjct: 613 DIIDTQLDSTMPYTLKETAEYGDPQDAYEYRYLRSYDPYYNLSPERSLPPTYVDAALDDG 672
Query: 561 RVHPAHALKFFMKLK----EVNAPVYLRVETKSGHMGAS 595
+V ++ + + + + + R+ GH G S
Sbjct: 673 QVIYYQPARYVAQRRSCATDRDPDLVFRIRMVGGHSGPS 711
>gb|AAF17628.1|AC009978_4 (AC009978) T23E18.8 [Arabidopsis thaliana]
Length = 137
Score = 80.8 bits (196), Expect = 4e-14
Identities = 45/112 (40%), Positives = 60/112 (53%), Gaps = 19/112 (16%)
Query: 504 IDMLRFHKLYIGSVWIPEYGNPDDPKDREFLLKYSPYHNV-RPQE--------YPPTLIY 554
+DMLRFHK IG W +YG ++ ++ +L+KYSP HNV RP E YP T++
Sbjct: 1 MDMLRFHKFTIGHAWTSDYGCSENEEEFHWLIKYSPLHNVKRPWEQQTDHLVQYPSTMLL 60
Query: 555 TGLHDDRVHPAHALKFFMKLKEVNA----------PVYLRVETKSGHMGASP 596
T HDDRV P H+LK L+ V P+ R+E K+GH P
Sbjct: 61 TADHDDRVVPLHSLKLLATLQHVLCTSLDNSPQMNPIIGRIEVKAGHGAGRP 112
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.319 0.141 0.422
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 258503872
Number of Sequences: 2977
Number of extensions: 12415848
Number of successful extensions: 30036
Number of sequences better than 1.0e-10: 56
Number of HSP's better than 0.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 29734
Number of HSP's gapped (non-prelim): 91
length of query: 614
length of database: 189,106,746
effective HSP length: 55
effective length of query: 559
effective length of database: 156,189,961
effective search space: 87310188199
effective search space used: 87310188199
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 168 (69.9 bits)