BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0770 (ugd) DE:UDP-glucose dehydrogenase (ugd)
(427 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||H75095 udp-glucose dehydrogenase (ugd) PAB0770 - Pyrococcus... 859 0.0
gi|11498204 UDP-glucose dehydrogenase (ugd-2) [Archaeoglobus ful... 653 0.0
gi|11497917 UDP-glucose dehydrogenase (ugd-1) [Archaeoglobus ful... 470 e-131
gb|AAG18685.1| (AE004973) UDP-glucose dehydrogenase; Ugd [Haloba... 377 e-103
pir||H70301 nucleotide sugar dehydrogenase - Aquifex aeolicus >g... 345 7e-94
gb|AAG19454.1| (AE005038) UDP-glucose dehydrogenase; Udg1 [Halob... 341 1e-92
gi|10956342 pXO1-95 [Bacillus anthracis] >gi|7474336|pir||G59102... 338 7e-92
pir||F69727 biosynthesis of teichuronic acid (UDP-glucose 6-dehy... 330 2e-89
pir||A70067 NDP-sugar dehydrogenase homolog ywqF - Bacillus subt... 320 2e-86
gb|AAG26472.1|AF285774_12 (AF285774) putative UDP-glucose dehydr... 317 1e-85
gb|AAD43344.1|AF159428_1 (AF159428) putative UDP-glucose dehydro... 309 5e-83
pir||S74698 UDP-glucose dehydrogenase - Synechocystis sp. (strai... 306 3e-82
gb|AAK41109.1| UDP-glucose 6-dehydrogenase (ugd) [Sulfolobus sol... 302 7e-81
emb|CAB57493.1| (Y18930) udp-glucose dehydrogenase [Sulfolobus s... 302 7e-81
sp|O54068|UDG_RHIME UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDRO... 301 1e-80
pir||T46573 UDPglucose 6-dehydrogenase (EC 1.1.1.22) [validated]... 301 1e-80
pir||H83203 GDP-mannose 6-dehydrogenase AlgD PA3540 [imported] -... 295 5e-79
sp|P11759|ALGD_PSEAE GDP-MANNOSE 6-DEHYDROGENASE (GMD) >gi|65967... 294 9e-79
pir||F82659 UDP-glucose dehydrogenase XF1606 [imported] - Xylell... 293 2e-78
sp|O05973|UDG_RICPR UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDRO... 291 1e-77
gb|AAF23790.1|AF213822_5 (AF213822) UDP-glucose dehydrogenase [Z... 290 2e-77
sp|O07299|ALGD_PSESH GDP-MANNOSE 6-DEHYDROGENASE (GMD) >gi|21607... 287 2e-76
sp|P51585|ALGD_AZOVI GDP-MANNOSE 6-DEHYDROGENASE (GMD) >gi|10019... 284 1e-75
pir||H83393 probable nucleotide sugar dehydrogenase PA2022 [impo... 276 4e-73
pir||B83202 probable nucleotide sugar dehydrogenase PA3559 [impo... 275 5e-73
pir||G69988 NDP-sugar dehydrogenase homolog ytcA - Bacillus subt... 273 3e-72
emb|CAA11569.1| (AJ223832) hypothetical protein [Mycobacterium a... 272 8e-72
emb|CAA72087.1| (Y11203) UDP-glucose dehydrogenase [Acetobacter ... 269 4e-71
emb|CAB58323.1| (AL121855) UDP-glucose/GDP-mannose family dehydr... 269 5e-71
pir||C70526 probable UDP-glucose dehydrogenase - Mycobacterium t... 261 8e-69
sp|O86422|UDG_PSEAE UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDRO... 241 1e-62
gb|AAD44217.2|AF143772_23 (AF143772) GdhgA [Mycobacterium avium] 240 2e-62
gb|AAD20371.1| (AF125999) UDP-D-glucose-dehydrogenase gdhgA [Myc... 239 5e-62
sp|Q58454|YA54_METJA HYPOTHETICAL PROTEIN MJ1054 >gi|2129344|pir... 226 5e-58
pir||JC2525 UDP-glucose dehydrogenase (EC 1.1.99.-) - Xanthomona... 224 1e-57
gb|AAF98561.1|AC013427_4 (AC013427) Strong similarity to UDP-Glu... 223 3e-57
dbj|BAB11006.1| (AB009054) UDP-glucose dehydrogenase [Arabidopsi... 214 1e-54
dbj|BAA99938.1| (AP001309) UDP-glucose dehydrogenase [Arabidopsi... 213 3e-54
sp|Q96558|UGDH_SOYBN UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDR... 213 4e-54
gb|AAF04455.1|AF053973_1 (AF053973) UDP-glucose dehydrogenase [P... 211 1e-53
pir||T51527 UDP-glucose dehydrogenase-like protein - Arabidopsis... 210 3e-53
sp|O70199|UGDH_RAT UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROG... 205 1e-51
gi|4507813 UDP-glucose dehydrogenase [Homo sapiens] >gi|11435916... 204 2e-51
gi|6678499 UDP-glucose dehydrogenase [Mus musculus] >gi|6136117|... 204 2e-51
sp|O02373|UGDH_DROME UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDR... 201 1e-50
gb|AAC97125.1| (AF001310) UDP-glucose dehydrogenase [Drosophila ... 201 1e-50
sp|P12378|UGDH_BOVIN UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDR... 201 1e-50
pir||JE0353 uridine diphosphoglucose dehydrogenase (EC 1.-.-.-) ... 200 3e-50
pir||E69211 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase -... 199 5e-50
pir||A54926 UDPglucose 6-dehydrogenase (EC 1.1.1.22) - bovine >g... 198 8e-50
sp|Q19905|UGDH_CAEEL PROBABLE UDP-GLUCOSE 6-DEHYDROGENASE (UDP-G... 196 6e-49
pir||G75173 udp-n-acetyl-d-mannosaminuronic acid dehydrogenase P... 189 4e-47
pir||F71153 probable Vi polysaccharide biosynthesis protein - Py... 184 1e-45
pir||F75096 udp-n-acetyl-d-mannosaminuronic acid dehydrogenase P... 181 1e-44
dbj|BAB07427.1| (AP001519) nucleotide sugar dehydrogenase [Bacil... 176 5e-43
pir||B71041 probable UDP-N-acetyl-D-mannosaminuronic acid dehydr... 175 1e-42
dbj|BAA77737.1| (AB008676) UDP-glucose-6-dehydrogenase [Escheric... 174 2e-42
pir||A81290 probable UDPglucose 6-dehydrogenase (EC 1.1.1.22) Cj... 174 2e-42
gb|AAG35229.1| (AF176369) UDP-glucose-6-dehydrogenase [Escherich... 173 3e-42
sp|P76373|UDG_ECOLI UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDRO... 172 8e-42
sp|Q57871|Y428_METJA HYPOTHETICAL PROTEIN MJ0428 >gi|2129342|pir... 170 3e-41
sp|O33952|UDG8_ECOLI UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDR... 170 3e-41
gb|AAD50493.1|AF172324_11 (AF172324) UDP-Glc-6-dehydrogenase Ugd... 170 3e-41
pir||S70888 nucleotide sugar dehydrogenase homolog - Vibrio chol... 169 4e-41
pir||T44338 hypothetical protein wbfV [imported] - Vibrio choler... 166 3e-40
emb|CAB43615.1| (AJ239004) uridine diphosphate glucose dehydroge... 165 8e-40
sp|Q45410|EPSD_BURSO NDP-N-ACETYL-D-GALACTOSAMINURONIC ACID DEHY... 163 4e-39
sp|Q47329|UDG5_ECOLI UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDR... 163 4e-39
emb|CAB05929.1| (Z83335) uridine diphosphate glucose dehydrogena... 163 4e-39
pir||H72358 lipopolysaccharide biosynthesis protein - Thermotoga... 163 4e-39
sp|Q04873|UDG_SALTY UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDRO... 162 9e-39
gb|AAC45348.1| (U90519) putative UDP-glucose dehydrogenase [Esch... 161 1e-38
gb|AAD10180.1| (AF026471) Cps2K [Streptococcus pneumoniae] 161 1e-38
sp|Q04872|UDG1_ECOLI UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDR... 160 3e-38
gb|AAF67264.1|AF169324_2 (AF169324) BcbB [Pasteurella multocida] 160 3e-38
sp|P37791|UDG_SHIFL UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDRO... 159 8e-38
pir||T44829 probable NDP-N-acetyl-D-galactosaminuronic acid dehy... 159 8e-38
pir||B82264 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase V... 155 7e-37
pir||F82417 UDP-glucose 6-dehydrogenase VCA0780 [imported] - Vib... 155 7e-37
gb|AAC46098.1| (U81973) Cap5O [Staphylococcus aureus] 155 1e-36
gi|9632145 PBCV-1 UDP-glucose dehydrogenase [Paramecium bursaria... 153 3e-36
gb|AAC67251.2| (AF067175) UDP-glucose dehydrogenase [Pasteurella... 153 3e-36
emb|CAB46919.2| (AJ242946) putative UDP-glucose dehydrogenase [S... 153 3e-36
gb|AAB49444.1| (U73374) Cap8O [Staphylococcus aureus] 150 2e-35
gb|AAF08248.1|AF170495_9 (AF170495) UDP-N-acetylglucosamine-2-ep... 148 1e-34
sp|Q07172|UDG_STRPY UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDRO... 141 1e-32
gb|AAD56735.1|AF125164_8 (AF125164) UDP-ManNAc dehydrogenase [Ba... 138 1e-31
pdb|1DLJ|A Chain A, The First Structure Of Udp-Glucose Dehydroge... 138 2e-31
pir||B49350 hypothetical protein 379 (nfrC 3' region) - Escheric... 137 3e-31
sp|P39861|CAPL_STAAU CAPL PROTEIN >gi|506708|gb|AAA64651.1| (U10... 136 5e-31
sp|P27829|WECC_ECOLI UDP-N-ACETYL-D-MANNOSAMINURONIC ACID DEHYDR... 136 5e-31
sp|Q57346|UDG_STRPN UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDRO... 132 7e-30
gb|AAC43311.1| (U15171) UDP-glucose dehydrogenase [Streptococcus... 132 9e-30
gb|AAF33466.1| (AF233324) 90% identity with E. coli UDP-N-acetyl... 129 6e-29
pir||S30681 hypothetical protein o379 - Escherichia coli >gi|148... 128 1e-28
sp|Q04972|VIPA_SALTI VI POLYSACCHARIDE BIOSYNTHESIS PROTEIN VIPA... 128 1e-28
emb|CAA78147.1| (Z12159) uridine diphosphate glucose dehydrogena... 128 1e-28
gb|AAF23997.1| (AF035937) WbpO [Pseudomonas aeruginosa] 127 2e-28
pir||T44509 Vi polysaccharide biosynthetic protein [imported] - ... 125 7e-28
pir||T44520 lipopolysaccharide biosynthesis protein [imported] -... 125 7e-28
gb|AAD40718.1|AF048749_14 (AF048749) putative UDP-glucose-6 dehy... 118 1e-25
pir||T44842 probable UDPglucose 6-dehydrogenase (EC 1.1.1.22) [i... 117 3e-25
pir||A83252 probable UDP-glucose/GDP-mannose dehydrogenase WbpA ... 116 4e-25
gb|AAA84869.1| (U34305) ORF1; Method: conceptual translation su... 116 5e-25
pir||S69821 NDP-sugar dehydrogenase homolog lmbL - Streptomyces ... 115 1e-24
pir||S44959 lmbL protein - Streptomyces lincolnensis 115 1e-24
pir||C82713 polysaccharide biosynthetic protein XF1183 [imported... 111 2e-23
emb|CAB82012.1| (AL161755) putative nucleotide-sugar dehydrogena... 108 1e-22
gb|AAC05135.1| (AF049126) UDP glucose 6-dehydrogenase [Homo sapi... 100 4e-20
gb|AAC12870.1| (AF044332) UDP-ManNAc dehydrogenase; RffD [Pectob... 87 5e-16
gb|AAD45294.1|AF156256_2 (AF156256) putative dehydrogenase [Vibr... 79 8e-14
>pir||H75095 udp-glucose dehydrogenase (ugd) PAB0770 - Pyrococcus abyssi
(strain Orsay) >gi|5458581|emb|CAB50069.1| (AJ248286)
UDP-glucose dehydrogenase (ugd) [Pyrococcus abyssi]
Length = 427
Score = 859 bits (2194), Expect = 0.0
Identities = 427/427 (100%), Positives = 427/427 (100%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG
Sbjct: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVK 120
KYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVK
Sbjct: 61 KYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVK 120
Query: 121 STVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDER 180
STVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDER
Sbjct: 121 STVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDER 180
Query: 181 TKKVLEKLYEPFNAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSWKVF 240
TKKVLEKLYEPFNAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSWKVF
Sbjct: 181 TKKVLEKLYEPFNAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSWKVF 240
Query: 241 EGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQPLKL 300
EGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQPLKL
Sbjct: 241 EGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQPLKL 300
Query: 301 IELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDPKAMENF 360
IELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDPKAMENF
Sbjct: 301 IELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDPKAMENF 360
Query: 361 KRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFESLDYSGKIVIDGRRVRSAEKTAK 420
KRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFESLDYSGKIVIDGRRVRSAEKTAK
Sbjct: 361 KRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFESLDYSGKIVIDGRRVRSAEKTAK 420
Query: 421 IYEGVCW 427
IYEGVCW
Sbjct: 421 IYEGVCW 427
>gi|11498204 UDP-glucose dehydrogenase (ugd-2) [Archaeoglobus fulgidus]
>gi|7431387|pir||D69324 UDP-glucose dehydrogenase
(ugd-2) homolog - Archaeoglobus fulgidus
>gi|2650028|gb|AAB90645.1| (AE001064) UDP-glucose
dehydrogenase (ugd-2) [Archaeoglobus fulgidus]
Length = 465
Score = 653 bits (1667), Expect = 0.0
Identities = 309/427 (72%), Positives = 380/427 (88%), Gaps = 4/427 (0%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
M ++I+GSGYVG+VTG+GF +LG+ ++F+DVDE KV ++N+++PPIYE GLEELM++ +G
Sbjct: 43 MKIAILGSGYVGIVTGIGFAELGHEIVFIDVDERKVEMLNSSKPPIYERGLEELMKKNRG 102
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVK 120
KY AT +YREA+ +S++TFI VGTPSK DG+IDL Y ++A+KEIGKALK DNFH+VVVK
Sbjct: 103 KYRATTDYREALESSELTFICVGTPSKGDGSIDLKYAESASKEIGKALKNNDNFHVVVVK 162
Query: 121 STVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDER 180
STV+PGTTE I+PI+EK SGKKAF+DFGLAMNPEFLREG A+ DF NPDRIVIGV+DER
Sbjct: 163 STVVPGTTEDKIKPIIEKESGKKAFEDFGLAMNPEFLREGNAVYDFFNPDRIVIGVKDER 222
Query: 181 TKKVLEKLYEPFNAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSWKVF 240
TK VLE+LY+PF+ PKL T+IKTAEMIKYASNAFLATKISFANEIGNICKKL ID +KVF
Sbjct: 223 TKSVLEELYKPFDCPKLITEIKTAEMIKYASNAFLATKISFANEIGNICKKLRIDVYKVF 282
Query: 241 EGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQPLKL 300
EGVGLDHRI+P FFR+GIGFGGSCFPKD++ALI+K+EELGE+P ILKAV++VNERQPLK+
Sbjct: 283 EGVGLDHRINPSFFRAGIGFGGSCFPKDVRALIRKSEELGENPKILKAVMEVNERQPLKM 342
Query: 301 IELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDPKAMENF 360
IELLKKH+PNL+ K+GVLGLAFKP+TDDVRE+RA ++K LLEEGA++IAYDPKA+ENF
Sbjct: 343 IELLKKHIPNLRGKKIGVLGLAFKPDTDDVRESRAIPIVKALLEEGAEIIAYDPKAIENF 402
Query: 361 KRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFESLDYSGKIVIDGRRVRSAEKTAK 420
++F+P Q+ YANSAE+V+ + D +LI+TEW++FE LDYSGKIVIDGRRV A K AK
Sbjct: 403 RKFFP----QVEYANSAEDVITKSDAVLIVTEWKEFEELDYSGKIVIDGRRVEKAMKEAK 458
Query: 421 IYEGVCW 427
IY+GVCW
Sbjct: 459 IYKGVCW 465
>gi|11497917 UDP-glucose dehydrogenase (ugd-1) [Archaeoglobus fulgidus]
>gi|7431386|pir||F69287 UDP-glucose dehydrogenase
(ugd-1) homolog - Archaeoglobus fulgidus
>gi|2650332|gb|AAB90929.1| (AE001084) UDP-glucose
dehydrogenase (ugd-1) [Archaeoglobus fulgidus]
Length = 324
Score = 470 bits (1197), Expect = e-131
Identities = 227/312 (72%), Positives = 277/312 (88%), Gaps = 1/312 (0%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
M VSIIG GYVGLVTG+GF +LGN V+FVD + K++ IN+ PPIYE GLEEL+++ +G
Sbjct: 1 MKVSIIGCGYVGLVTGLGFAELGNPVVFVDSNGSKIKSINDLIPPIYEPGLEELIKKNEG 60
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVK 120
K+YATN+Y EA+ NS+++FI VGTPSK DG++DL V+ A+ ++GKAL EK+ FH++VVK
Sbjct: 61 KFYATNDYFEALDNSEVSFICVGTPSKEDGSLDLRQVEEASSKLGKALAEKE-FHVIVVK 119
Query: 121 STVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDER 180
STVLPGTTE ++PI+EK SGKKAF DFGLAMNPEFLREG A++DF NPDRIVIGV+DER
Sbjct: 120 STVLPGTTENFVKPIIEKESGKKAFDDFGLAMNPEFLREGNAVEDFFNPDRIVIGVKDER 179
Query: 181 TKKVLEKLYEPFNAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSWKVF 240
TK VLE+LY+PF+ PKL T+IKTAEMIKYASNAFLATKISFANEIGNICKKLGID +KVF
Sbjct: 180 TKSVLEELYKPFDCPKLITEIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDVYKVF 239
Query: 241 EGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQPLKL 300
EGVGLDHRI+P FFR+GIGFGGSCFPKD++ALI+K+EELGED ILKAV++VNE+QPLK+
Sbjct: 240 EGVGLDHRINPSFFRAGIGFGGSCFPKDVRALIRKSEELGEDLQILKAVIEVNEKQPLKM 299
Query: 301 IELLKKHVPNLK 312
IELLKKH+P+L+
Sbjct: 300 IELLKKHIPDLR 311
>gb|AAG18685.1| (AE004973) UDP-glucose dehydrogenase; Ugd [Halobacterium sp. NRC-1]
Length = 430
Score = 377 bits (957), Expect = e-103
Identities = 196/436 (44%), Positives = 279/436 (63%), Gaps = 15/436 (3%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
M VSI+GSGYVG F +G+ V+ VD+D+ V IN + PI+E GL++L+ G
Sbjct: 1 MRVSIVGSGYVGTTVAACFTDMGHDVVNVDIDQDIVDAINAGKAPIHEPGLDDLLATHGG 60
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVK 120
A E +L +D+TF+ + TPSK DG+ID + ++ AA+ +G L+EKD H+VV K
Sbjct: 61 DTLAATTDYEDVLETDVTFLALPTPSKEDGSIDTSIIEAAAETLGDTLREKDGDHVVVTK 120
Query: 121 STVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDER 180
STV+P TT + PIL SGK+ D +AMNPEFLREG A++DF NPD+IV G E
Sbjct: 121 STVIPRTTTETLAPILADASGKQLGADLHVAMNPEFLREGTAVEDFQNPDKIVFGSDSET 180
Query: 181 TKKVLEKLYEPF----NAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDS 236
L ++++P +A + T ++ AEMIKYA+NAFLA+K+S N+IGNICK+ G+D+
Sbjct: 181 AIDTLHEIFKPLIEASDATVVETGVEEAEMIKYANNAFLASKVSLINDIGNICKEFGVDA 240
Query: 237 WKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQ 296
++V + +GLD RIS F RSG+G+GGSCF KD A+I A E G +P +L+A + VN+RQ
Sbjct: 241 YEVADAIGLDDRISERFLRSGLGWGGSCFGKDTNAIIHAATETGYEPAMLEAAVAVNDRQ 300
Query: 297 PLKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDPKA 356
P +L+ LL H +++ +V VLGLAFKP TDDVR++RA VI L E GA V AYDP A
Sbjct: 301 PERLLSLLDDH-GDVESERVAVLGLAFKPGTDDVRDSRAIPVINGLQERGANVAAYDPVA 359
Query: 357 MENFKRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFESLD-----YSGKIVIDGRR 411
EN + +PD I Y ++ ++ L + ++ T+W +F LD ++V+DGRR
Sbjct: 360 AENMRTHFPD----IEYTDAPQDALADASACVVCTDWDEFAVLDDEFDAMETRVVVDGRR 415
Query: 412 VRSAEKTAKIYEGVCW 427
+ + YEG+ W
Sbjct: 416 I-IERRDGLTYEGLTW 430
>pir||H70301 nucleotide sugar dehydrogenase - Aquifex aeolicus
>gi|2982765|gb|AAC06391.1| (AE000669) nucleotide sugar
dehydrogenase [Aquifex aeolicus]
Length = 437
Score = 345 bits (875), Expect = 7e-94
Identities = 192/433 (44%), Positives = 273/433 (62%), Gaps = 18/433 (4%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEF-- 58
M +S+IG GYVGLVT F LG+ V+ V+ KV ++ + PIYE GLEEL++E
Sbjct: 1 MKLSVIGGGYVGLVTAACFSHLGHEVLVVEKIPEKVELLRRGKSPIYEPGLEELLREGIN 60
Query: 59 KGKYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVV 118
+G+ T + +E I S++ FI VGTPS PDG+ DL+ V+ A+ K + D++ ++V
Sbjct: 61 EGRLSFTTDIKEGIEFSEVIFICVGTPSNPDGSADLSQVEEVARFTAKYM---DSYKLLV 117
Query: 119 VKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQD 178
KSTV GT V R + K+ +F +A NPEFLREG A+KDFL PDRIV+GV+
Sbjct: 118 NKSTVPVGTQRKVKRTVRLYLKNKEL--EFDVASNPEFLREGHAVKDFLEPDRIVVGVES 175
Query: 179 ERTKKVLEKLYEPFNA---PKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGID 235
ER K+VL ++Y+P P L T+ TAE+IKYASN FLATKISF N I ++C+K+G +
Sbjct: 176 ERAKEVLLEIYKPITDKGFPILITNPPTAEIIKYASNTFLATKISFINMISDLCEKVGAN 235
Query: 236 SWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNER 295
+V +G+G D RI F R+G+G+GGSC PKD KA I+ EELG D ILK L +NE
Sbjct: 236 VEEVAQGMGYDKRIGKEFLRAGLGWGGSCLPKDTKAFIRILEELGVDATILKGALGINES 295
Query: 296 QPLKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDPK 355
+ +L++ LK + LK + + GL+FKPNTDD+RE + V+++LL EGAK+ AYDPK
Sbjct: 296 RVDRLLQKLKDALWILKGKTIAIWGLSFKPNTDDIREAPSLKVVERLLREGAKIRAYDPK 355
Query: 356 AMENFKRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFESLDYSG-------KIVID 408
A ENFKR + + G + Y + + + + +LILTEW +F+ + I+ID
Sbjct: 356 ATENFKRVFIE-GEDLRYFDDKYKAVEGAEALLILTEWDEFKRANLERVKRLMELPIIID 414
Query: 409 GRRVRSAEKTAKI 421
GR + ++ +
Sbjct: 415 GRNIYDPQEVRNL 427
>gb|AAG19454.1| (AE005038) UDP-glucose dehydrogenase; Udg1 [Halobacterium sp.
NRC-1]
Length = 426
Score = 341 bits (865), Expect = 1e-92
Identities = 190/438 (43%), Positives = 281/438 (63%), Gaps = 23/438 (5%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
M+VSI+GSGYVG F +LG+ V+ VDVD V IN+ PI+E GL E + G
Sbjct: 1 MDVSIVGSGYVGTTIAACFAELGHTVVNVDVDADVVAAINDGDAPIHEPGLAERIDAHAG 60
Query: 61 -KYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVV 119
+ AT +Y EA+ ++D+TF+ + TP++ DG+ID + +++ A +G+AL D+ H+VVV
Sbjct: 61 TRLRATTDY-EAVRDTDVTFLALPTPAREDGSIDTSIMESGAASLGEALAGADD-HMVVV 118
Query: 120 KSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDE 179
KSTV+PGTTE V+ L F D LAMNPEFLR G A+ DF +PD++V G + +
Sbjct: 119 KSTVVPGTTEDVVESALVS----AGFDDPLLAMNPEFLRMGSAVDDFRHPDKVVFGARRD 174
Query: 180 RTKKVLEKLYEPF-----NAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGI 234
L ++EP +A + T ++ AEMIKYA+NAFLA+K+S N++GNICK+LG+
Sbjct: 175 AAYDQLHAVFEPLLADAGDATVVETGLREAEMIKYANNAFLASKVSLINDLGNICKELGV 234
Query: 235 DSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNE 294
D+++V + + D RIS F RSG+G+GGSCFPKD+ A+ A++ G +P +L+A ++VN+
Sbjct: 235 DAYEVADAIAEDDRISGRFLRSGVGWGGSCFPKDVAAITAAAKDAGYEPAMLEAAVEVND 294
Query: 295 RQPLKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDP 354
RQP +L+ LL HV ++ +V VLGL+FKP TDD+R TRA VI L + A V+AYDP
Sbjct: 295 RQPERLLSLLDGHV-DVAGERVAVLGLSFKPGTDDIRGTRAVPVIDGLQDREADVVAYDP 353
Query: 355 KAMENFKRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFESLD-----YSGKIVIDG 409
A E P+V +YA+SA L + +++T+W +F +LD + ++V+DG
Sbjct: 354 VAAEKMAEQRPEV----TYADSAAGALADAVGAVVVTDWDEFAALDDEFDAMAERVVVDG 409
Query: 410 RRVRSAEKTAKIYEGVCW 427
RRV + Y+G+ W
Sbjct: 410 RRVVDPQADL-TYDGLTW 426
>gi|10956342 pXO1-95 [Bacillus anthracis] >gi|7474336|pir||G59102 hypothetical
protein pXO1-95 - Bacillus anthracis virulence plasmid
pXO1 >gi|4894311|gb|AAD32399.1|AAD32399 (AF065404)
pXO1-95 [Bacillus anthracis]
Length = 443
Score = 338 bits (858), Expect = 7e-92
Identities = 181/395 (45%), Positives = 258/395 (64%), Gaps = 11/395 (2%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQE--F 58
MN+SI+G+GYVGLVTG+ ++G+ V +D+DE KV+ + PI+E LEELM+
Sbjct: 1 MNISIVGTGYVGLVTGVCLSEVGHNVTCIDIDEEKVKKMKLGYSPIFEPCLEELMKNNII 60
Query: 59 KGKYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVV 118
KG+ + T NY + ++I +I VGTP K DG+ DL+++K AA I + +K N I+V
Sbjct: 61 KGRLHFTTNYVDGADGAEIFYIAVGTPQKEDGSADLSFIKQAAINIARTIK---NDVIIV 117
Query: 119 VKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQD 178
VKSTV GT + IL+ + + NPEFLREG A+ D DRIVIG ++
Sbjct: 118 VKSTVPVGTNIYIKNLILKNLNYDVKVD---IISNPEFLREGSAVNDTFYGDRIVIGSEN 174
Query: 179 ERTKKVLEKLYEPFNAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSWK 238
+ + V+E++Y+PF P TDI++AEMIKYASN FLATKISF N I N+C+ +G D K
Sbjct: 175 KTSANVMEEVYKPFGTPIFKTDIQSAEMIKYASNTFLATKISFINGIANLCEMVGADVEK 234
Query: 239 VFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQPL 298
V +G+G D RI F +GIG+GGSCFPKD AL+K +E L +L++V+++N+ Q
Sbjct: 235 VAQGMGQDKRIGSQFLNAGIGYGGSCFPKDTHALVKVSESLQHKFHLLESVIKLNKNQQT 294
Query: 299 KLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDPKAME 358
LIE +KK ++ K+ +LGL+FKPNTDD+RE + + +KL+EEGA+VIAYDP A++
Sbjct: 295 VLIEKIKKRFGSIVGKKIALLGLSFKPNTDDLREAPSIPIARKLVEEGAQVIAYDPVAIK 354
Query: 359 NFKRFYPDVGRQISYANSAEEVLREVDVILILTEW 393
N + P +++ Y S E L E D+ L+LTEW
Sbjct: 355 NAREVLP---KEVHYVYSTMEALTEADIALVLTEW 386
>pir||F69727 biosynthesis of teichuronic acid (UDP-glucose 6-dehydrogenase) tuaD
- Bacillus subtilis >gi|2454559|gb|AAB94865.1|
(AF015609) UDP-glucose dehydrogenase [Bacillus subtilis]
>gi|2636084|emb|CAB15575.1| (Z99122) UDP-glucose
6-dehydrogenase [Bacillus subtilis]
Length = 461
Score = 330 bits (837), Expect = 2e-89
Identities = 181/424 (42%), Positives = 269/424 (62%), Gaps = 18/424 (4%)
Query: 3 VSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQE--FKG 60
+++IG+GYVGLV+G F ++GN+V+ D+DE K+R + N PIYE GL +L+++
Sbjct: 4 IAVIGTGYVGLVSGTCFAEIGNKVVCCDIDESKIRSLKNGVIPIYEPGLADLVEKNVLDQ 63
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVK 120
+ TN+ AI SDI +I VGTP G DLTYVK AAK IG+ L + + ++V K
Sbjct: 64 RLTFTNDIPSAIRASDIIYIAVGTPMSKTGEADLTYVKAAAKTIGEHL---NGYKVIVNK 120
Query: 121 STVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDER 180
STV GT + +++ I++K S K F + NPEFLREG A+ D +N +R VIG +
Sbjct: 121 STVPVGTGK-LVQSIVQKAS--KGRYSFDVVSNPEFLREGSAIHDTMNMERAVIGSTSHK 177
Query: 181 TKKVLEKLYEPFNAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSWKVF 240
++E+L++PF+AP + T++++AEMIKYA+NAFLATKISF N+I NIC+++G D KV
Sbjct: 178 AAAIIEELHQPFHAPVIKTNLESAEMIKYAANAFLATKISFINDIANICERVGADVSKVA 237
Query: 241 EGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQPLKL 300
+GVGLD RI F ++GIGFGGSCFPKD AL++ A+ G +++AV++ NE+Q + +
Sbjct: 238 DGVGLDSRIGRKFLKAGIGFGGSCFPKDTTALLQIAKSAGYPFKLIEAVIETNEKQRVHI 297
Query: 301 IELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDPKAMENF 360
++ L + ++K + VLGLAFKPNT+DVR A +I L + GA V AYDP A+
Sbjct: 298 VDKLLTVMGSVKGRTISVLGLAFKPNTNDVRSAPALDIIPMLQQLGAHVKAYDPIAIPEA 357
Query: 361 KRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFESLD-------YSGKIVIDGRRVR 413
+G Q+ Y + + D LILT+W + + ++ ++IDGR +
Sbjct: 358 SAI---LGEQVEYYTDVYAAMEDTDACLILTDWPEVKEMELVKVKTLLKQPVIIDGRNLF 414
Query: 414 SAEK 417
S E+
Sbjct: 415 SLEE 418
>pir||A70067 NDP-sugar dehydrogenase homolog ywqF - Bacillus subtilis
>gi|1894744|emb|CAB07444.1| (Z92952) product similar to
Pseudomonas aeruginosa GDP-mannose 6-dehydrogenase
protein [Bacillus subtilis] >gi|2636148|emb|CAB15640.1|
(Z99122) similar to NDP-sugar dehydrogenase [Bacillus
subtilis]
Length = 440
Score = 320 bits (811), Expect = 2e-86
Identities = 173/419 (41%), Positives = 254/419 (60%), Gaps = 18/419 (4%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQE--F 58
MN+++IG+GYVGLVTG+ ++G+ V +D+D K+ + PI+E GLEELM++
Sbjct: 1 MNITVIGTGYVGLVTGVSLSEIGHHVTCIDIDAHKIDEMRKGISPIFEPGLEELMRKNTA 60
Query: 59 KGKYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVV 118
G+ +Y + + +DI FI VGTP K DG +L + +AAK I K +K +VV
Sbjct: 61 DGRLNFETSYEKGLAQADIIFIAVGTPQKSDGHANLEQITDAAKRIAKHVKRDT---VVV 117
Query: 119 VKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQD 178
KSTV GT + +I ++ ++ + +A NPEFLREG A+ D + DRIVIG D
Sbjct: 118 TKSTVPVGTND-LINGLITEHLAEPV--SISVASNPEFLREGSAIYDTFHGDRIVIGTAD 174
Query: 179 ERTKKVLEKLYEPFNAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSWK 238
E+T LE+L+ PF P TDI++AEMIKYASNAFLATKISF NEI NIC+K+G D
Sbjct: 175 EKTANTLEELFRPFQIPIYQTDIRSAEMIKYASNAFLATKISFINEISNICEKVGADIEA 234
Query: 239 VFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQPL 298
V G+G D RI F ++GIG+GGSCFPKD AL++ A + D +LK+V++VN Q
Sbjct: 235 VAYGMGQDKRIGSQFLKAGIGYGGSCFPKDTNALVQIAGNVEHDFELLKSVIKVNNNQQA 294
Query: 299 KLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDPKAME 358
L++ + + + +LGL+FKPNTDD+RE + ++ +L A++ AYDP A+
Sbjct: 295 MLVDKALNRLGGVTGKTIALLGLSFKPNTDDMREAPSIVIADRLAALDARIRAYDPIAVS 354
Query: 359 NFKRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFESLDYSG-------KIVIDGR 410
+ K P + + Y + EE ++ D ++ILT+W D + + ++ DGR
Sbjct: 355 HAKHVLP---QAVEYKETIEEAVKGSDAVMILTDWADIKQFPLAAYQDLMETPLIFDGR 410
>gb|AAG26472.1|AF285774_12 (AF285774) putative UDP-glucose dehydrogenase [Bacteroides
fragilis]
Length = 440
Score = 317 bits (804), Expect = 1e-85
Identities = 177/434 (40%), Positives = 263/434 (59%), Gaps = 19/434 (4%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEF-- 58
M ++I+G+GYVGLVTG F ++G V VDV E K+ + PIYE GLE+++
Sbjct: 1 MKIAIVGTGYVGLVTGTCFSEMGVDVTCVDVIESKIDNLKKGIIPIYEPGLEDMVHRNYN 60
Query: 59 KGKYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVV 118
G+ T + + + ++ F VGTP DG+ DL YV A+ IGK + +++ +VV
Sbjct: 61 AGRLKFTTSLASCLNDVEVVFSAVGTPPDEDGSADLKYVLEVARTIGKTM---NHYVLVV 117
Query: 119 VKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQD 178
KSTV GT + V I + + +F +A NPEFL+EG A+ DF+ PDR+V+GV+
Sbjct: 118 TKSTVPVGTAQQVKATIRGELDKRGLNLEFDVASNPEFLKEGDAVDDFMKPDRVVVGVES 177
Query: 179 ERTKKVLEKLYEPF---NAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGID 235
ER K ++E+LY+PF N +FTDI +AEMIKYA+N+ LAT+ISF N+I N+C+ +G +
Sbjct: 178 ERAKSIMERLYKPFMMNNYRLIFTDIPSAEMIKYAANSMLATRISFMNDIANLCELVGAN 237
Query: 236 SWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNER 295
V +G+G D RI F G G+GGSCFPKD+KALIK A++ G +LKAV +VN
Sbjct: 238 VNMVRKGIGADSRIGSKFLYPGCGYGGSCFPKDVKALIKTADKNGYSMRVLKAVEEVNNS 297
Query: 296 QPLKLI-ELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDP 354
Q L +L++ NL ++ + GL+FKP TDD+RE A ++I K+L G V AYDP
Sbjct: 298 QKSILFNKLIRYFDGNLSGKRIALWGLSFKPETDDMREAPALVLIDKILSCGGLVKAYDP 357
Query: 355 KAMENFKRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFESLDY-------SGKIVI 407
A+E KR +G I YAN + + + D +L++TEW++F + + ++I
Sbjct: 358 IAVEECKR---RIGDSIEYANDMYDAVLDADALLLVTEWKEFRMPSWGVLKKTMNRALII 414
Query: 408 DGRRVRSAEKTAKI 421
DGR + ++ +
Sbjct: 415 DGRNIYDRQELQSV 428
>gb|AAD43344.1|AF159428_1 (AF159428) putative UDP-glucose dehydrogenase [Burkholderia
pseudomallei]
Length = 466
Score = 309 bits (782), Expect = 5e-83
Identities = 173/449 (38%), Positives = 270/449 (59%), Gaps = 31/449 (6%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFK- 59
M ++IIG+GYVGLVTG ++G+ V +DVD K+ ++NN PI+E GL+E++ +
Sbjct: 1 MKITIIGTGYVGLVTGACLAEIGHDVFCLDVDPRKIDILNNGGMPIHEPGLQEIIARTRA 60
Query: 60 -GKYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVV 118
G+ + + ++ + +I FI VGTP DG+ DL YV AA+ IG+ + + ++V
Sbjct: 61 AGRIAFSTDIEASVAHGEIQFIAVGTPPDEDGSADLQYVLEAARNIGRHMT---GYKVIV 117
Query: 119 VKSTVLPGTTEGVIRPILEKYSGK----KAFQDFGLAMNPEFLREGVALKDFLNPDRIVI 174
KSTV GT + V I E + + A F + NPEFL+EG A+ DF+ PDRI+I
Sbjct: 118 DKSTVPVGTAQRVRAVIDEALAARGLAGSAEHRFSVVSNPEFLKEGAAVDDFMRPDRIII 177
Query: 175 GVQDERT----KKVLEKLYEPFNAPK---LFTDIKTAEMIKYASNAFLATKISFANEIGN 227
GV D+ ++ ++KLY PFN ++ D+++AE KYA+NA LAT+ISF NE+ N
Sbjct: 178 GVDDDAAGAIAREKMKKLYAPFNRNHERTIYMDVRSAEFSKYAANAMLATRISFMNEMSN 237
Query: 228 ICKKLGIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILK 287
+ ++G D + G+G D RI HF +G+G+GGSCFPKD++ALI+ A E G+ IL+
Sbjct: 238 LADRVGADIEALRRGIGSDPRIGYHFLYAGVGYGGSCFPKDVQALIRTASENGQPLRILE 297
Query: 288 AVLQVNERQPLKLIELL-KKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEG 346
AV VN Q L++ + K++ +L V GLAFKPNTDD+RE + +I LL G
Sbjct: 298 AVEDVNHAQKNVLLDKIEKRYGADLAGRTFAVWGLAFKPNTDDMREAPSRRLIASLLARG 357
Query: 347 AKVIAYDPKAMENFKRFY-------PDVGRQISYANSAEEVLREVDVILILTEWRDFESL 399
A V AYDP A++ +R + D ++++ +SA++ L D ++I+TEW++F+S
Sbjct: 358 AMVRAYDPVALDEARRVFALDLHDGADALARLAFVDSADDALAGADALVIVTEWKEFKSP 417
Query: 400 DYS-------GKIVIDGRRVRSAEKTAKI 421
D++ ++ DGR + + A++
Sbjct: 418 DFAHLKSVLKAPVIFDGRNLYEPDAMAEL 446
>pir||S74698 UDP-glucose dehydrogenase - Synechocystis sp. (strain PCC 6803)
>gi|1651923|dbj|BAA16849.1| (D90901) UDP-glucose
dehydrogenase [Synechocystis sp.]
Length = 453
Score = 306 bits (776), Expect = 3e-82
Identities = 180/447 (40%), Positives = 265/447 (59%), Gaps = 38/447 (8%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELM--QEF 58
M V +IG+GYVGLVTG+ +G++VI VD +E KV+++ Q PIYE GL ELM
Sbjct: 1 MRVCVIGTGYVGLVTGVCLAHIGHQVICVDNNEEKVKLMRAGQSPIYEPGLSELMVANME 60
Query: 59 KGKYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVV 118
G+ T + + + S I FI VGTP+ DG+ D YV+ A+ IG+ L E+ + ++V
Sbjct: 61 SGRLVFTTDLGKGVQESAILFIAVGTPALEDGSSDTRYVEAVARSIGEHLDEQ--YRVIV 118
Query: 119 VKSTVLPGTTEGVIRPILE------KYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRI 172
KSTV G+ + V + E + +G+ +F + NPEFLREG A+ D NPDRI
Sbjct: 119 NKSTVPIGSGDWVRMIVTEGNEAHQQQTGQAIAVNFDVVSNPEFLREGSAVYDTFNPDRI 178
Query: 173 VIGVQDERTKKVLEKLYEPF------------NAPKLFTDIKTAEMIKYASNAFLATKIS 220
V+G + + ++ +LY P P + TD+ +AEMIKYA+NAFLATKIS
Sbjct: 179 VLGGNNPQALALMRELYTPLIERRVGENPELPPVPVVMTDLSSAEMIKYAANAFLATKIS 238
Query: 221 FANEIGNICKKLGIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELG 280
F NE+ NIC ++G D +V +G+GLD RI F +GIG+GGSCFPKD+ ALI A++ G
Sbjct: 239 FINEVANICDRVGADVTQVAQGIGLDSRIGSKFLNAGIGWGGSCFPKDVSALIHTAKDYG 298
Query: 281 EDPIILKAVLQVNERQPLKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIK 340
IL AV++VN+ Q L ++E L++ + LK +G+LGL FKP+TDD+R+ A +I+
Sbjct: 299 YTTSILNAVVEVNQVQRLIVVEKLQQELKILKGKVIGLLGLTFKPDTDDMRDAPALNIIQ 358
Query: 341 KLLEEGAKVIAYDPKAMENFKRFYPDVGRQIS---YANSAEEVLREVDVILILTEWRDFE 397
+L GAKV AYDP ++ V +S ++ + + D ++++TEW++F
Sbjct: 359 QLNRLGAKVKAYDPIVSQS------GVSHGLSGVKIESTPAMLADQCDALILVTEWQEFL 412
Query: 398 SLDY-------SGKIVIDGRRVRSAEK 417
LD+ ++IDGR EK
Sbjct: 413 KLDFPVLASRMHQAVIIDGRNFLDKEK 439
>gb|AAK41109.1| UDP-glucose 6-dehydrogenase (ugd) [Sulfolobus solfataricus]
Length = 409
Score = 302 bits (764), Expect = 7e-81
Identities = 175/423 (41%), Positives = 259/423 (60%), Gaps = 29/423 (6%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
M + ++G G VGLVTG G+ V+ VD+D+ KV+ + + PIYE GL+EL+ + K
Sbjct: 1 MRIGVVGLGVVGLVTGAVLADQGHEVVGVDIDQNKVKGLQCNRSPIYEPGLDELLLKNKN 60
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVK 120
++ T +Y A+ + DI FITV TP+ +G + YV +AAK + LK IVVVK
Sbjct: 61 RFLFTTDY-SALKDVDIVFITVATPTV-EGKNYIGYVLDAAKTMKPYLKRDA---IVVVK 115
Query: 121 STVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDER 180
STV+PGT+ V + I+E+ + NPEFL+EG A+ D + PDRIVIG +
Sbjct: 116 STVVPGTSRKV-KQIVERE----------VVANPEFLKEGSAVIDTIKPDRIVIGSDSKA 164
Query: 181 TKKVLEKLYEPFNAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKL-GIDSWKV 239
V+E L+ L T I+ AEMIKYA+N+FLATKISF NEI N+C+ + D +
Sbjct: 165 AGDVIENLWSFTKTVVLRTSIEEAEMIKYAANSFLATKISFINEIANLCEVIPNCDVNTI 224
Query: 240 FEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQPLK 299
+ +GLD RI+P+F +G+G+GGSCFPKD A A ELGE+ I++A ++VNE +P +
Sbjct: 225 AKAIGLDKRIAPYFLNAGLGYGGSCFPKDTLAFASFARELGEELKIVEAAIKVNEERPRR 284
Query: 300 LIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDPKAMEN 359
++++++ + LK + +LG+AFKPNTDD RE+ A + K L++ GA VIAYDPKA +
Sbjct: 285 AVKIMEELLGELKGKTICILGIAFKPNTDDTRESVALKIAKLLVDIGANVIAYDPKAKTS 344
Query: 360 FKRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFESLDY--SGKIVIDGRRVRSAEK 417
+ +S EE ++ D ++I TEW +F +++ K V+DGRRV K
Sbjct: 345 L----------VEMVSSKEECVKRSDGVIIATEWDEFRGIEHMLKDKAVLDGRRVLDPNK 394
Query: 418 TAK 420
++
Sbjct: 395 MSR 397
>emb|CAB57493.1| (Y18930) udp-glucose dehydrogenase [Sulfolobus solfataricus]
Length = 409
Score = 302 bits (764), Expect = 7e-81
Identities = 175/423 (41%), Positives = 259/423 (60%), Gaps = 29/423 (6%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
M + ++G G VGLVTG G+ V+ VD+D+ KV+ + + PIYE GL+EL+ + K
Sbjct: 1 MRIGVVGLGVVGLVTGAVLADQGHEVVGVDIDQNKVKGLQCNRSPIYEPGLDELLLKNKN 60
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVK 120
++ T +Y A+ + DI FITV TP+ +G + YV +AAK + LK IVVVK
Sbjct: 61 RFLFTTDY-SALKDVDIVFITVATPTV-EGKNYIGYVLDAAKTMKPYLKRDA---IVVVK 115
Query: 121 STVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDER 180
STV+PGT+ V + I+E+ + NPEFL+EG A+ D + PDRIVIG +
Sbjct: 116 STVVPGTSRKV-KQIVERE----------VVANPEFLKEGSAVIDTIKPDRIVIGSDSKA 164
Query: 181 TKKVLEKLYEPFNAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKL-GIDSWKV 239
V+E L+ L T I+ AEMIKYA+N+FLATKISF NEI N+C+ + D +
Sbjct: 165 AGDVIENLWSFTKTVVLRTSIEEAEMIKYAANSFLATKISFINEIANLCEVIPNCDVNTI 224
Query: 240 FEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQPLK 299
+ +GLD RI+P+F +G+G+GGSCFPKD A A ELGE+ I++A ++VNE +P +
Sbjct: 225 AKAIGLDKRIAPYFLNAGLGYGGSCFPKDTLAFASFARELGEELKIVEAAIKVNEERPRR 284
Query: 300 LIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDPKAMEN 359
++++++ + LK + +LG+AFKPNTDD RE+ A + K L++ GA VIAYDPKA +
Sbjct: 285 AVKIMEELLGELKGKTICILGIAFKPNTDDTRESVALKIAKLLVDIGANVIAYDPKAKTS 344
Query: 360 FKRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFESLDY--SGKIVIDGRRVRSAEK 417
+ +S EE ++ D ++I TEW +F +++ K V+DGRRV K
Sbjct: 345 L----------VEMVSSKEECVKRSDGVIIATEWDEFRGIEHMLKDKAVLDGRRVLDPNK 394
Query: 418 TAK 420
++
Sbjct: 395 MSR 397
>sp|O54068|UDG_RHIME UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH)
Length = 437
Score = 301 bits (762), Expect = 1e-80
Identities = 173/436 (39%), Positives = 260/436 (58%), Gaps = 27/436 (6%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQE--F 58
M +++IG+GYVGLV+G+ F G+ V+ VD DE K+ + Q PI+E GL+ L+
Sbjct: 1 MKITMIGAGYVGLVSGVCFADFGHDVVCVDKDEGKISALKKGQIPIFEPGLDHLVASNVA 60
Query: 59 KGKYYATNNYREAILNSDITFITVGTPSKP-DGTIDLTYVKNAAKEIGKALKEKDNFHIV 117
G+ T++ + A+ SD+ FI VGTPS+ DG DL+YV AA+EI L+ F +V
Sbjct: 61 SGRLNFTDDLKTAVAASDVVFIAVGTPSRRGDGHADLSYVYAAAREIAANLQ---GFTVV 117
Query: 118 VVKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQ 177
V KSTV GT + V R I E D + NPEFLREG A++DF PDRIVIGV
Sbjct: 118 VTKSTVPVGTGDEVERIIRETNPAA----DVTVVSNPEFLREGAAIEDFKRPDRIVIGVD 173
Query: 178 --DERTKKVLEKLYEPF---NAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKL 232
D R ++V+ ++Y P +P +FT +T+E+IKYA NAFLA KI+F NEI ++C+K+
Sbjct: 174 GSDGRAREVMTEVYRPLYLNQSPLVFTTRRTSELIKYAGNAFLAMKITFINEIADLCEKV 233
Query: 233 GIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQV 292
G + V G+GLD RI F +G G+GGSCFPKD AL+K A++ +++ + V
Sbjct: 234 GANVQDVARGIGLDGRIGSKFLHAGPGYGGSCFPKDTLALVKTAQDHDTPVRLVETTVAV 293
Query: 293 NERQPLKL-IELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIA 351
N+ + + +++ +++ K+ VLGL FKPNTDD+R++ A V++ L + GA+V
Sbjct: 294 NDNRKRAMGRKVIAAAGGDIRGSKIAVLGLTFKPNTDDMRDSPAIAVVQALQDAGARVTG 353
Query: 352 YDPKAMENFKRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFESLDY-------SGK 404
YDP+ MEN ++ + A E E D ++I+TEW +F +LD+
Sbjct: 354 YDPEGMENARKLI----EGLDCARDPYEAAAEADALVIITEWNEFRALDFDRLKSTMKTP 409
Query: 405 IVIDGRRVRSAEKTAK 420
+++D R + ++ AK
Sbjct: 410 LLVDLRNIYRKDEVAK 425
>pir||T46573 UDPglucose 6-dehydrogenase (EC 1.1.1.22) [validated] -
Sinorhizobium meliloti >gi|2959984|emb|CAA10918.1|
(AJ222661) UDP-glucose dehydrogenase [Sinorhizobium
meliloti]
Length = 437
Score = 301 bits (762), Expect = 1e-80
Identities = 174/436 (39%), Positives = 259/436 (58%), Gaps = 27/436 (6%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQE--F 58
M +++IG+GYVGLV+G+ F G+ V+ VD DE K+ + Q PI+E GL+ L+
Sbjct: 1 MKITMIGAGYVGLVSGVCFADFGHDVVCVDKDEGKISALKKGQIPIFEPGLDHLVASNVA 60
Query: 59 KGKYYATNNYREAILNSDITFITVGTPSKP-DGTIDLTYVKNAAKEIGKALKEKDNFHIV 117
G+ T++ + A+ SD+ FI VGTPS+ DG DL+YV AA+EI L+ F +V
Sbjct: 61 SGRLNFTDDLKTAVAASDVVFIAVGTPSRRGDGHADLSYVYAAAREIASNLQ---GFTVV 117
Query: 118 VVKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQ 177
V KSTV GT + V R I E D + NPEFLREG A++DF PDRIVIGV
Sbjct: 118 VTKSTVPVGTGDEVERIIRETNPAV----DVTVVSNPEFLREGAAIEDFKRPDRIVIGVD 173
Query: 178 --DERTKKVLEKLYEPF---NAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKL 232
D R ++V+ ++Y P +P +FT +T+E+IKYA NAFLA KI+F NEI ++C+K+
Sbjct: 174 GSDGRAREVMTEVYRPLYLNQSPLVFTTRRTSELIKYAGNAFLAMKITFINEIADLCEKV 233
Query: 233 GIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQV 292
G + V G+GLD RI F +G G+GGSCFPKD AL+K A++ +++ + V
Sbjct: 234 GANVQDVARGIGLDGRIGSKFLHAGPGYGGSCFPKDTLALVKTAQDHDTPVRLVETTVAV 293
Query: 293 NERQPLKL-IELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIA 351
N+ + + +++ +++ K VLGL FKPNTDD+R+T A V++ L + GA+V
Sbjct: 294 NDNRKRAMGRKVIAAAGGDIRGSKYAVLGLTFKPNTDDMRDTPAIAVVQALQDAGARVTG 353
Query: 352 YDPKAMENFKRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFESLDY-------SGK 404
YDP+ MEN ++ + A E E D ++I+TEW +F +LD+
Sbjct: 354 YDPEGMENARKLI----EGLDCARDPYEAAAEADALVIITEWNEFRALDFDRLKSTMKTP 409
Query: 405 IVIDGRRVRSAEKTAK 420
+++D R + ++ AK
Sbjct: 410 LLVDLRNIYRKDEVAK 425
>pir||H83203 GDP-mannose 6-dehydrogenase AlgD PA3540 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9949690|gb|AAG06928.1|AE004774_6 (AE004774)
GDP-mannose 6-dehydrogenase AlgD [Pseudomonas
aeruginosa]
Length = 436
Score = 295 bits (748), Expect = 5e-79
Identities = 171/443 (38%), Positives = 260/443 (58%), Gaps = 23/443 (5%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFK- 59
M +SI G GYVG V G+ VI VDV K+ +IN + PI E GLE L+Q+ +
Sbjct: 1 MRISIFGLGYVGAVCAGCLSARGHEVIGVDVSSTKIDLINQGKSPIVEPGLEALLQQGRQ 60
Query: 60 -GKYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVV 118
G+ T ++++A+L+SD++FI VGTPSK +G +DL Y++ +EIG A++EK H VV
Sbjct: 61 TGRLSGTTDFKKAVLDSDVSFICVGTPSKKNGDLDLGYIETVCREIGFAIREKSERHTVV 120
Query: 119 VKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQD 178
V+STVLPGT V+ P++E SGKKA DFG+ NPEFLRE A+KD+ P VIG D
Sbjct: 121 VRSTVLPGTVNNVVIPLIEDCSGKKAGVDFGVGTNPEFLRESTAIKDYDFPPMTVIGELD 180
Query: 179 ERTKKVLEKLYEPFNAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSWK 238
++T +LE++Y +AP + ++ AEMIKY N + A K++FANEIGNI K +G+D +
Sbjct: 181 KQTGDLLEEIYRELDAPIIRKTVEVAEMIKYTCNVWHAAKVTFANEIGNIAKAVGVDGRE 240
Query: 239 VFEGVGLDHR--ISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQ 296
V + + DH+ +S ++ R G FGGSC PKD++AL +A +L + +L ++++ N Q
Sbjct: 241 VMDVICQDHKLNLSRYYMRPGFAFGGSCLPKDVRALTYRASQLDVEHPMLGSLMRSNSNQ 300
Query: 297 PLKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDPKA 356
K +L+ H KVG+LGL+FK TDD+RE+ + + L+ +G ++ +D
Sbjct: 301 VQKAFDLITSH----DTRKVGLLGLSFKAGTDDLRESPLVELAEMLIGKGYELRIFDRNV 356
Query: 357 ---------MENFKRFYPDVGRQISYANSAEEVLREVDVILILTE---WRDFESLDYSGK 404
E + P V + + +EV+ DV+++ + D + SGK
Sbjct: 357 EYARVHGANKEYIESKIPHVSSLL--VSDLDEVVASSDVLVLGNGDELFVDLVNKTPSGK 414
Query: 405 IVIDGRRVRSAEKTAKIYEGVCW 427
++D TA+ EG+CW
Sbjct: 415 KLVDLVGFMPHTTTAQA-EGICW 436
>sp|P11759|ALGD_PSEAE GDP-MANNOSE 6-DEHYDROGENASE (GMD) >gi|65967|pir||DEPSGD GDPmannose
6-dehydrogenase (EC 1.1.1.132) - Pseudomonas aeruginosa
>gi|45268|emb|CAA68425.1| (Y00337) GDPmannose
dehydrogenase (AA 1-436) [Pseudomonas aeruginosa]
Length = 436
Score = 294 bits (746), Expect = 9e-79
Identities = 171/443 (38%), Positives = 259/443 (57%), Gaps = 23/443 (5%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFK- 59
M +SI G GYVG V G+ VI VDV K+ +IN + PI E GLE L+Q+ +
Sbjct: 1 MRISIFGLGYVGAVCAGCLSARGHEVIGVDVSSTKIDLINQGKSPIVEPGLEALLQQGRQ 60
Query: 60 -GKYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVV 118
G+ T ++++A+L+SD++FI VGTPSK +G +DL Y++ +EIG A++EK H VV
Sbjct: 61 TGRLSGTTDFKKAVLDSDVSFICVGTPSKKNGDLDLGYIETVCREIGFAIREKSERHTVV 120
Query: 119 VKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQD 178
V+STVLPGT V+ P++E SGKKA DFG+ NPEFLRE A+KD+ P VIG D
Sbjct: 121 VRSTVLPGTVNNVVIPLIEDCSGKKAGVDFGVGTNPEFLRESTAIKDYDFPPMTVIGELD 180
Query: 179 ERTKKVLEKLYEPFNAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSWK 238
++T +LE++Y +AP + ++ AEMIKY N + A K++FANEIGNI K +G+D +
Sbjct: 181 KQTGDLLEEIYRELDAPIIRKTVEVAEMIKYTCNVWHAAKVTFANEIGNIAKAVGVDGRE 240
Query: 239 VFEGVGLDHR--ISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQ 296
V + + DH+ +S ++ R G FGGSC PKD++AL +A +L + +L ++++ N Q
Sbjct: 241 VMDVICQDHKLNLSRYYMRPGFAFGGSCLPKDVRALTYRASQLDVEHPMLGSLMRSNSNQ 300
Query: 297 PLKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDPKA 356
K +L+ H KVG+LGL+FK TDD+RE+ + + L+ +G + +D
Sbjct: 301 VQKAFDLITSH----DTRKVGLLGLSFKAGTDDLRESPLVELAEMLIGKGYEFRIFDRNV 356
Query: 357 ---------MENFKRFYPDVGRQISYANSAEEVLREVDVILILTE---WRDFESLDYSGK 404
E + P V + + +EV+ DV+++ + D + SGK
Sbjct: 357 EYARVHGANKEYIESKIPHVSSLL--VSDLDEVVASSDVLVLGNGDELFVDLVNKTPSGK 414
Query: 405 IVIDGRRVRSAEKTAKIYEGVCW 427
++D TA+ EG+CW
Sbjct: 415 KLVDLVGFMPHTTTAQA-EGICW 436
>pir||F82659 UDP-glucose dehydrogenase XF1606 [imported] - Xylella fastidiosa
(strain 9a5c) >gi|9106655|gb|AAF84415.1|AE003988_2
(AE003988) UDP-glucose dehydrogenase [Xylella
fastidiosa]
Length = 450
Score = 293 bits (743), Expect = 2e-78
Identities = 176/446 (39%), Positives = 255/446 (56%), Gaps = 25/446 (5%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQ--EF 58
M V+I G+GYVGLVTG ++G+ V+ VD+++ KV +N PIYE GLE +++
Sbjct: 1 MRVAIFGTGYVGLVTGTCLAEVGHEVLCVDINQAKVDGLNCGVIPIYEPGLEPMVKANHA 60
Query: 59 KGKYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVV 118
G+ T + AI + +ITFI VGTP DG DL YV A+ IG+ + D IVV
Sbjct: 61 TGRLRFTTDSVAAIAHGEITFIAVGTPPDEDGAADLQYVLAVARTIGQCI---DRSTIVV 117
Query: 119 VKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQD 178
KSTV GT + V I + + F + NPEFL+EG A+ D + PDRIVIG +
Sbjct: 118 NKSTVPVGTADQVRAAIQHEMDVRGVDFKFEVVSNPEFLKEGDAVADCMRPDRIVIGARS 177
Query: 179 ERTKKVLEKLYEPFNAPK---LFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGID 235
+ +LY PFN + D+++AE+ KYA+NA LATKISF NE+ NI + +G D
Sbjct: 178 RDAVVRMRRLYAPFNRNHDRIVEMDVRSAELTKYAANAMLATKISFMNEVANIAEYVGAD 237
Query: 236 SWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNER 295
V +G+G D RI +F G+G+GGSCFPKD+KAL + A++ G DP +L AV VN
Sbjct: 238 IEYVRKGIGSDPRIGWYFIYPGVGYGGSCFPKDVKALARTAQQYGVDPKLLNAVEDVNHA 297
Query: 296 QPLKLIELLKKHV------PNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKV 349
Q L EL+ +H L V GLAFKPNTDD+RE + ++ +L + GA+V
Sbjct: 298 QKGHLFELMLRHYGCSGESTVLAGKTFAVWGLAFKPNTDDMREAPSCRLLVQLWKAGAQV 357
Query: 350 IAYDPKAMENFKRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFESLDY-------S 402
AYDP+AM+ +R + + + + +A L+ D ++++TEW+ F S D+
Sbjct: 358 RAYDPEAMQEARRIFGE-RDDLVFCETAYAALQCADALIVVTEWKQFRSPDFFVIRDALK 416
Query: 403 GKIVIDGRRV---RSAEKTAKIYEGV 425
++ DGR + + E+ Y G+
Sbjct: 417 DAVIFDGRNLYDPQEIEEAGLAYYGI 442
>sp|O05973|UDG_RICPR UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|7431391|pir||E71638 UDP-glucose
6-dehydrogenase (udg) RP779 - Rickettsia prowazekii
>gi|2073510|emb|CAA72478.1| (Y11785) UDP-glucose
dehydrogenase [Rickettsia prowazekii]
>gi|3861306|emb|CAA15205.1| (AJ235273) UDP-GLUCOSE
6-DEHYDROGENASE (udg) [Rickettsia prowazekii]
Length = 434
Score = 291 bits (736), Expect = 1e-77
Identities = 174/434 (40%), Positives = 255/434 (58%), Gaps = 24/434 (5%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEF-- 58
MN++ IGSGYVGLV+G+ LG+ V +D D+ K+ +N PIYE L+E ++
Sbjct: 1 MNITFIGSGYVGLVSGIIMGYLGHNVTCLDNDDVKISKLNKKILPIYEAKLDEYLKHALE 60
Query: 59 KGKYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVV 118
+ TN Y N D FITVGTPSK G DL YV +A ++ K + + ++V
Sbjct: 61 SDRLKFTNIYSNEFRNFDAIFITVGTPSKELGEADLKYVYDAVDKVSKHINKDC---LIV 117
Query: 119 VKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQD 178
+KSTV PG+ +I Y K F F +A NPEFLREG A++DFL PDRIV+GV +
Sbjct: 118 IKSTVPPGSCNNIIA-----YLKAKGFS-FNVASNPEFLREGSAVEDFLYPDRIVVGVNN 171
Query: 179 ERTKKVLEKLYEPF---NAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGID 235
+ ++ +L K+Y P A L T++ T+E+IKY SN+FLATKI+F NE+ ++C+K+G +
Sbjct: 172 KESEALLRKIYAPLIEQGAKFLVTNLVTSELIKYVSNSFLATKIAFINEMADLCEKIGAN 231
Query: 236 SWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNER 295
+ +GVGLD RI +F +G GFGGSCFPKD+ AL E D ILK+V++ N+
Sbjct: 232 IKDLSQGVGLDQRIGRNFLNAGPGFGGSCFPKDILALNNLVENHKIDCKILKSVIKSNKL 291
Query: 296 QPLKLIELLKKHVP-NLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDP 354
+P ++ + + +LK + +LGL +K TDDVR + A +I LL + V A+DP
Sbjct: 292 RPSNMVAKIATLLDGDLKGRNIAILGLTYKAGTDDVRASPAIEIITILLNKDVYVKAFDP 351
Query: 355 KAMENFKRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFESLDY-------SGKIVI 407
+EN K+ + + Y SA E + VD+I+I TEW +F+ L++ ++I
Sbjct: 352 IGLENAKKNLEH--KNLLYFASAVEACKSVDIIVIATEWSEFKELNWQEIYNLVKSPMII 409
Query: 408 DGRRVRSAEKTAKI 421
D R + E KI
Sbjct: 410 DLRNILDNEVMKKI 423
>gb|AAF23790.1|AF213822_5 (AF213822) UDP-glucose dehydrogenase [Zymomonas mobilis]
Length = 437
Score = 290 bits (735), Expect = 2e-77
Identities = 170/442 (38%), Positives = 264/442 (59%), Gaps = 28/442 (6%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEF-- 58
M +++IGSGYVGLV+G F +G+ VI VD D+ K+ ++ PIYE GL +++
Sbjct: 1 MRITMIGSGYVGLVSGACFSDIGHNVICVDHDQEKIALLQKGVMPIYEPGLADMVANNVK 60
Query: 59 KGKYYATNNYREAILNSDITFITVGTPSKP-DGTIDLTYVKNAAKEIGKALKEKDNFHIV 117
G+ +N+ ++ ++D FI VGTPS+ DG DL+YV AAKEI ++ + +V
Sbjct: 61 AGRLSFSNDLASSVKDADAVFIAVGTPSRRGDGHADLSYVFAAAKEIAASVSDNT---VV 117
Query: 118 VVKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQ 177
V KSTV GT + V R I E KK + +A NPEFLREG A+ DF PDRIVIG +
Sbjct: 118 VDKSTVPVGTGDEVERIIREIAPDKKIW----VASNPEFLREGAAIGDFKRPDRIVIGTE 173
Query: 178 DERTKKVLEKLYEPF---NAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGI 234
+ +++++++Y P +P LFT ++AE+IKYASNAFLATKI+F NE+ ++C+ +G
Sbjct: 174 NPEAREIMQEIYRPLYLNQSPILFTSRRSAELIKYASNAFLATKITFINEMADLCEAVGG 233
Query: 235 DSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNE 294
D V G+G D+RI F +G G+GGSCFPKD AL+K AE ++++V+ N
Sbjct: 234 DVQDVARGIGADNRIGSKFLHAGPGYGGSCFPKDTLALLKTAENFATPLRVVESVVTANN 293
Query: 295 -RQPLKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYD 353
R+ ++L+ +++ K+G+LGL FKPNTDD+R+ + +I+ L + GA + AYD
Sbjct: 294 IRKRAMARKVLQAIGKDMRGQKIGLLGLPFKPNTDDMRDAPSLALIQGLEDAGAIIHAYD 353
Query: 354 PKAMENFKRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFESLD-------YSGKIV 406
P+ M + P+V + + +V + + ++I+TEW F +LD ++
Sbjct: 354 PEGMVQARPLLPNV----IFEDEPYKVAEKAEALVIVTEWDAFRALDLKRIAGLLKTPLL 409
Query: 407 IDGRRV---RSAEKTAKIYEGV 425
+D R + A+K +Y G+
Sbjct: 410 LDLRNIYTEEEAKKAGLVYHGI 431
>sp|O07299|ALGD_PSESH GDP-MANNOSE 6-DEHYDROGENASE (GMD) >gi|2160786|gb|AAB58939.1|
(AF001555) GDP mannose dehydrogenase [Pseudomonas
syringae pv. phaseolicola]
Length = 438
Score = 287 bits (726), Expect = 2e-76
Identities = 172/445 (38%), Positives = 255/445 (56%), Gaps = 25/445 (5%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQE--F 58
M +SI G GYVG V G+ V+ VD+ K+ +INN + PI E GLEEL+Q+
Sbjct: 1 MRISIFGLGYVGAVCAGCLSARGHDVVGVDISSTKIDLINNGKSPIVEPGLEELLQKGIS 60
Query: 59 KGKYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVV 118
GK T ++ EAI +D++ I VGTPSK +G ++L Y+++ +EIG L++K H +V
Sbjct: 61 TGKLRGTTDFAEAIRATDLSMICVGTPSKKNGDLELDYIESVCREIGYVLRDKATRHTIV 120
Query: 119 VKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQD 178
V+STVLPGT V+ PILE SGKKA DFG+A+NPEFLRE A+KD+ P VIG D
Sbjct: 121 VRSTVLPGTVANVVIPILEDCSGKKAGVDFGVAVNPEFLRESTAIKDYDLPPMTVIGEFD 180
Query: 179 ERTKKVLEKLYEPFNAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSWK 238
+ + VL+ LYE +AP + DI AEMIKY N + ATK++FANEIGNI K +G+D +
Sbjct: 181 KASGDVLQSLYEELDAPIIRKDIAVAEMIKYTCNVWHATKVTFANEIGNIAKAVGVDGRE 240
Query: 239 VFEGVGLDH--RISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQ 296
V + V D +S ++ R G FGGSC PKD++AL +A L + +L ++++ N Q
Sbjct: 241 VMDVVCQDKALNLSQYYMRPGFAFGGSCLPKDVRALTYRASSLDVEAPLLNSLMRSNTSQ 300
Query: 297 PLKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDPKA 356
++ V + KV +LGL+FK TDD+RE+ + + L+ +G + +D
Sbjct: 301 VQNAFDM----VASYDTRKVALLGLSFKAGTDDLRESPLVELAEMLIGKGFDLSIFDSNV 356
Query: 357 ---------MENFKRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFESL---DYSGK 404
+ + P V ++ + ++V+ + DVI++ F +L GK
Sbjct: 357 EYARVHGANKDYIESKIPHVSSLLN--SDFDQVINDSDVIILGNRDERFRALANKTPEGK 414
Query: 405 IVID--GRRVRSAEKTAKIYEGVCW 427
VID G + + + EG+CW
Sbjct: 415 RVIDLVGFMTNATSEDGRA-EGICW 438
>sp|P51585|ALGD_AZOVI GDP-MANNOSE 6-DEHYDROGENASE (GMD) >gi|1001937|gb|AAB01487.1|
(U11240) GDP-mannose dehydrogenase [Azotobacter
vinelandii]
Length = 436
Score = 284 bits (719), Expect = 1e-75
Identities = 170/443 (38%), Positives = 255/443 (57%), Gaps = 23/443 (5%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEF-- 58
M +SI G GYVG V G+ V+ VD+ K+ +IN + PI E GL EL+ E
Sbjct: 1 MRISIFGLGYVGAVCAGCLSGRGHEVVGVDISAAKIDMINQGKSPIVEPGLGELLAEGVK 60
Query: 59 KGKYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVV 118
G+ T N EA+L ++++ + VGTPSK +G ++L Y++ +++G AL++K H VV
Sbjct: 61 TGRLRGTTNVTEAVLATELSMLCVGTPSKLNGDLELDYIEEVCRQMGSALRDKTERHTVV 120
Query: 119 VKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQD 178
V+STVLPGT V+ PILE++SGKKA DFG+A+NPEFLRE A+KD+ P VIG D
Sbjct: 121 VRSTVLPGTVHNVVIPILEEFSGKKAGVDFGVAVNPEFLRESTAIKDYNFPPMTVIGELD 180
Query: 179 ERTKKVLEKLYEPFNAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSWK 238
+ + + L +Y +AP + I AEMIKY N + ATK++FANEIGNI K G+D +
Sbjct: 181 KASGRRLASIYAELDAPIVRKGIAVAEMIKYTCNVWHATKVTFANEIGNIAKAAGVDGRE 240
Query: 239 VFEGVGLDHR--ISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQ 296
V E V +D++ +S ++ R G+ FGGSC PKD+ AL +A + ++ ++++ N Q
Sbjct: 241 VMEVVCMDNKLNLSQYYMRPGLAFGGSCLPKDVSALSYRAHLWDIEAPLISSLMRSNAAQ 300
Query: 297 PLKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDPKA 356
K +++ KH KV +LGL+FK TDD+RE+ + + L+ +G K+ +D
Sbjct: 301 VQKAYDMIDKH----GSRKVALLGLSFKAGTDDLRESPQLELAEMLIGKGFKLSIFDSNV 356
Query: 357 MENFKRFYPDVGRQIS---------YANSAEEVLREVDVILILTEWRDFESLDY---SGK 404
+ R + G I + ++V+ E DVI++ FE L +GK
Sbjct: 357 --EYARDHGANGHYIKNEIPHVSALLQSDLDKVVAEADVIVLGNADPRFEKLAKDVPAGK 414
Query: 405 IVIDGRRVRSAEKTAKIYEGVCW 427
VID ++TA EG+CW
Sbjct: 415 KVIDLVGF-MPQRTAGAAEGICW 436
>pir||H83393 probable nucleotide sugar dehydrogenase PA2022 [imported] -
Pseudomonas aeruginosa (strain PAO1)
>gi|9948026|gb|AAG05410.1|AE004628_8 (AE004628) probable
nucleotide sugar dehydrogenase [Pseudomonas aeruginosa]
Length = 453
Score = 276 bits (698), Expect = 4e-73
Identities = 165/443 (37%), Positives = 252/443 (56%), Gaps = 21/443 (4%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEF-- 58
M + +IG+GYVGLVT F ++GN+V V+ D +V + + PIYE GLE ++++
Sbjct: 1 MRLCVIGAGYVGLVTAACFAEMGNQVRCVERDRERVARLRRGEMPIYEPGLESILRDQLD 60
Query: 59 KGKYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVV 118
+ T + E + ++++ FI VGTP DG+ DL++V A+++G L++ IVV
Sbjct: 61 AARLTFTASLAEGLADAEVVFIAVGTPCGEDGSADLSHVLAVAEQLGAQLRQAC---IVV 117
Query: 119 VKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQD 178
KSTV GT E V I + ++ +A NPEFL+EG A+ DF PDR++IG +
Sbjct: 118 NKSTVPVGTAERVEEIIRLGLARRRKRFRVAVASNPEFLKEGSAVDDFRRPDRVIIGSAE 177
Query: 179 ERTKKVLEKLYEPF---NAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGID 235
+ + L +LY PF + L + AE KYA+NAFLATKISF NE+ +C G+D
Sbjct: 178 TQAGETLRQLYAPFLRNHERVLLMGRREAEFSKYAANAFLATKISFMNEMAGLCALTGVD 237
Query: 236 SWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNER 295
V G+G D RI HF +G G+GGSCFPKD++ALI+ AE+ G D IL+AV N R
Sbjct: 238 IEDVRRGMGSDKRIGTHFIYAGCGYGGSCFPKDVRALIRSAEQQGYDSQILRAVEARNAR 297
Query: 296 QPLKLIELL-KKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDP 354
Q L E L + + V + GLAFKP TDD+RE + ++++ LL G +V A+DP
Sbjct: 298 QKELLFETLGELFQGRWQGRTVALWGLAFKPGTDDLREAPSLVLLEALLRHGVRVRAHDP 357
Query: 355 KAMENFKRFYPD--VGRQISYANSAEEVLREVDVILILTEWRDFESLDYS-------GKI 405
A YP+ +++ +S + D ++++TEW+ F D+ +
Sbjct: 358 VANAGVAARYPEAVACARLTLHDSPYAAVEGADALVLVTEWKQFRQPDFQKIRGSMRTPL 417
Query: 406 VIDGRRVRSAEKTAK---IYEGV 425
++DGR + + + A+ IY+G+
Sbjct: 418 LVDGRNLYAPARMAELGFIYQGI 440
>pir||B83202 probable nucleotide sugar dehydrogenase PA3559 [imported] -
Pseudomonas aeruginosa (strain PAO1)
>gi|9949711|gb|AAG06947.1|AE004776_10 (AE004776)
probable nucleotide sugar dehydrogenase [Pseudomonas
aeruginosa]
Length = 464
Score = 275 bits (697), Expect = 5e-73
Identities = 164/433 (37%), Positives = 246/433 (55%), Gaps = 17/433 (3%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEF-- 58
M +S+ GSGYVGLV ++G+ V+ +D+D KV + IYE GL+ L++E
Sbjct: 1 MKISVFGSGYVGLVQAAVLAEVGHDVLCMDIDRNKVERLAQGLASIYEPGLDALLREGLD 60
Query: 59 KGKYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVV 118
G+ +++ R A+ + + FI VGTP DG DL V A I + ++ IVV
Sbjct: 61 SGRLRFSSDARLAVEHGRVQFIAVGTPPGEDGAADLGAVFVVADAIAEHRRKPV---IVV 117
Query: 119 VKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQD 178
KSTV GT + + I + +F + NPEFL+EG A+ D PDRIV+G +
Sbjct: 118 EKSTVPVGTGDRLRAHIERRLEADGRELEFEIVSNPEFLKEGSAVADCRRPDRIVVGCDN 177
Query: 179 ERTKKVLEKLYEPFNAPK---LFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGID 235
E ++V+ +LYEPFN LF +++AE+ KYA+N LATKISF N+I + + LG D
Sbjct: 178 EEVRQVMRELYEPFNRNHDRMLFMGLRSAELTKYAANGMLATKISFINQIAELAEHLGAD 237
Query: 236 SWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNER 295
V +G+G D RI HF G G+GGSCFPKD++ALI AE+ +L+AV +N R
Sbjct: 238 IEAVRQGIGADPRIGYHFIYPGCGYGGSCFPKDMRALIHSAEQAHCSSDLLQAVEAINRR 297
Query: 296 QPLKLIELLKK-HVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDP 354
Q KL E ++ + +L+ + GLAFKPNTDD+R+ + +++ L GA+V AYDP
Sbjct: 298 QKHKLFERIRVFYDGDLRGKTFALWGLAFKPNTDDMRDAPSRELMEALWRHGAQVRAYDP 357
Query: 355 KAMENFKRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFESLDY-------SGKIVI 407
+AM+ +R Y ++S + E L D ++I TEW+ F++ D+ ++
Sbjct: 358 EAMQETQRLYGH-DERLSLMGTPEATLGGADALVICTEWQQFKAPDFELLKERLKAPVIF 416
Query: 408 DGRRVRSAEKTAK 420
DGR + E+ A+
Sbjct: 417 DGRNLYDPERMAR 429
>pir||G69988 NDP-sugar dehydrogenase homolog ytcA - Bacillus subtilis
>gi|2293289|gb|AAC00367.1| (AF008220) YtcA [Bacillus
subtilis] >gi|2635570|emb|CAB15064.1| (Z99119) similar
to NDP-sugar dehydrogenase [Bacillus subtilis]
Length = 428
Score = 273 bits (690), Expect = 3e-72
Identities = 151/426 (35%), Positives = 243/426 (56%), Gaps = 23/426 (5%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
M + ++G+GYVGL +G+ +I D D K+ + P YE GL + + G
Sbjct: 1 MKICVVGAGYVGLTLSAALASIGHDMICTDKDVKKIGQLKKGVIPFYEPGLSDAILRC-G 59
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVK 120
++ + ++ + FI VGTP + DG+ D +++ ++ +A++ ++ ++ K
Sbjct: 60 NLSFSSEVKSSMEECPVIFIAVGTPPRSDGSADTKALQSVIGDLSEAIR---SYKTIITK 116
Query: 121 STVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDER 180
STV PGT E + + ++ K F + NPEFLREG AL D L+PD+ VIGVQ+E
Sbjct: 117 STVPPGTNENIAKQLIASGVSKNLFN---IVSNPEFLREGNALYDMLHPDKTVIGVQEED 173
Query: 181 --TKKVLEKLYEPFNAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSWK 238
+ +++ +Y+ + P + T + AE+IKYA+N FLA KISF NE+ IC+ D
Sbjct: 174 HVSAAIVKSIYKHIDTPFIVTSLAGAELIKYANNFFLAAKISFINEMARICEAYQSDISD 233
Query: 239 VFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQPL 298
+ +GLD RI HF ++GIG+GGSCFPKDL+AL A+E + +L+AV +N+ Q
Sbjct: 234 ISRAIGLDPRIGKHFLQAGIGYGGSCFPKDLQALQFAAQEKNTETFLLRAVQHINDTQLG 293
Query: 299 KLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDPKAME 358
I+ ++ L+ K VLG++FKPNTDD+R ++A ++++L E G V AYDP+A+
Sbjct: 294 LYIKKIQSFFETLQGKKAAVLGISFKPNTDDIRNSQAVRLMERLAELGCDVHAYDPEAV- 352
Query: 359 NFKRFYPDVGRQ-ISYANSAEEVLREVDVILILTEWRDFESLDY-------SGKIVIDGR 410
P+ RQ ++ + A + + E D + + TEW +F + D+ G++VIDGR
Sbjct: 353 -----LPEHLRQHVTQHSQAFDAIEESDFLFLATEWSEFLAFDWKKAADIMKGRLVIDGR 407
Query: 411 RVRSAE 416
V E
Sbjct: 408 NVLKKE 413
>emb|CAA11569.1| (AJ223832) hypothetical protein [Mycobacterium avium subsp.
silvaticum]
Length = 411
Score = 272 bits (687), Expect = 8e-72
Identities = 150/367 (40%), Positives = 220/367 (59%), Gaps = 25/367 (6%)
Query: 65 TNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVKSTVL 124
T + + I ++D+ FI V TP G DLTYV + A +IG + D + ++V KSTV
Sbjct: 42 TTDRQRGIEHADVIFIAVPTPMGESGAADLTYVFSVADDIGSYI---DRYKVIVDKSTVP 98
Query: 125 PGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDERTKKV 184
GT + + I K Q+F + NPEFL++G A+ DF+ PDR+VIG +R ++
Sbjct: 99 VGTADQITAIIRSKTD-----QEFDVVSNPEFLKQGKAIADFMQPDRVVIGSDSKRALRI 153
Query: 185 LEKLYEPFNA---PKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSWKVFE 241
+E+LYEPF P + D+++AEM KYA+N FLATKISF NE+ N+C+K G D V E
Sbjct: 154 MEELYEPFLRTFHPLIAIDVRSAEMAKYAANCFLATKISFINEMSNLCEKAGADISAVRE 213
Query: 242 GVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQPL--- 298
+G D RI F GIG+GGSC PKD++AL+ A+ LG D +L+AV +VN+ Q
Sbjct: 214 AIGADKRIGYDFLFPGIGYGGSCLPKDVRALLYTADCLGSDMHLLRAVERVNDEQKAALV 273
Query: 299 -KLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDPKAM 357
K+I NL +++G+ GL+FKP TDDVR + ++ +KL+E GA V A+DP+AM
Sbjct: 274 SKIITRFGGSEKNLDGLRIGLWGLSFKPQTDDVRAAPSLVIAEKLVEFGATVCAFDPEAM 333
Query: 358 ENFKRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFESLDYS-------GKIVIDGR 410
E K+ +G I YA + + ++ D +L+LTEW+ F+ +S G +V DGR
Sbjct: 334 EQTKKV---LGDSIEYAGNMYDAVQGADALLLLTEWKQFQRPSWSRVRSAMRGCVVFDGR 390
Query: 411 RVRSAEK 417
+ E+
Sbjct: 391 NIYDPER 397
>emb|CAA72087.1| (Y11203) UDP-glucose dehydrogenase [Acetobacter xylinus]
Length = 449
Score = 269 bits (681), Expect = 4e-71
Identities = 153/412 (37%), Positives = 237/412 (57%), Gaps = 23/412 (5%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEF-- 58
M +++IG GYVGLV+G F + G V V+ + ++ + + PIYE GL+ L++E
Sbjct: 1 MRIAMIGGGYVGLVSGTCFAEFGTDVAIVETNPDRLTALREGRIPIYEPGLDRLVEENVE 60
Query: 59 KGKYYATNNYREAILNSDITFITVGTPSKP-DGTIDLTYVKNAAKEIGKALKEKDNFHIV 117
G+ ++ A+ +D F+ VGTPS+ DG D +YV A ++I + D + ++
Sbjct: 61 AGRLTFGDDIAAAVKGADAVFVAVGTPSRRGDGQADTSYVYAAVEQIARVA---DGYTVI 117
Query: 118 VVKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQ 177
V KSTV GT R I + + DF +A NPEFLREG A++DF+ PDR++IG
Sbjct: 118 VTKSTVPVGTG----REIAQIIRKTRPDLDFDVASNPEFLREGNAIQDFMRPDRVIIGTD 173
Query: 178 D------ERTKKVLEKLYEPF---NAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNI 228
ER + +L KLY P P +FT ++TAE+IKY++N+FLA KI+F NEI ++
Sbjct: 174 QYKPEGTERAQNILRKLYRPLYLLETPIVFTGLETAELIKYSANSFLAMKITFINEISDL 233
Query: 229 CKKLGIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKA 288
C+K+G + V +GLD RI F GFGGSCFPKD +AL G +++
Sbjct: 234 CEKVGANVNDVARSIGLDGRIGKKFLHPSPGFGGSCFPKDTRALTAIGRNAGSPVRLIET 293
Query: 289 VLQVNERQPLKLIE-LLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGA 347
+ VNE++ + E ++ ++ + +GVLGL FKP TDD+RE + V+ L + GA
Sbjct: 294 TVAVNEQRMKDMGERVITFAGGDVSGLTIGVLGLTFKPETDDMREAASIPVLDMLDKGGA 353
Query: 348 KVIAYDPKAMENFKRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFESL 399
K+ A+DP M + P + + ++Y A + + D++++LTEW +F SL
Sbjct: 354 KIRAFDPAGMTTAR---PVLPQSVTYCTDALDAAKGADILVVLTEWNEFRSL 402
>emb|CAB58323.1| (AL121855) UDP-glucose/GDP-mannose family dehydrogenase
[Streptomyces coelicolor A3(2)]
Length = 441
Score = 269 bits (680), Expect = 5e-71
Identities = 168/449 (37%), Positives = 252/449 (55%), Gaps = 30/449 (6%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEF-- 58
M VS+ G GYVG V+ +G++V+ VDV++ KV ++N+ + P+ EE + EL+ E
Sbjct: 1 MRVSVFGLGYVGCVSAACLAGMGHQVVGVDVNQAKVDLVNDGKAPVVEERIGELIAEVVG 60
Query: 59 KGKYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNF---H 115
G AT + REAI+ S+I+ + VGTPS+P+G++ TY++ +EIG AL E+ H
Sbjct: 61 SGALRATGDVREAIMESEISLVCVGTPSEPNGSLCTTYLERVTEEIGTALAERGGGGGRH 120
Query: 116 IVVVKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIG 175
VV +ST+LPGT ++ PILEKY G A DFG+A+NPEFLREG +++DF +P + VIG
Sbjct: 121 TVVFRSTMLPGTCANLLVPILEKYVGGTAGVDFGVAVNPEFLREGTSVRDFFDPPKTVIG 180
Query: 176 VQDERTKKVLEKLYEPFNAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGID 235
D + LY+ + TAE IKYA NAF KI FANE+G +C LG+D
Sbjct: 181 ELDAAGGDAVLALYDSLPGEVFRVPVATAEAIKYADNAFHGLKIGFANELGAVCHALGVD 240
Query: 236 SWKVFEGVGLDHR--ISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVN 293
S +V + D + ISP + R G FGGSC PKDL++L+ A+ IL VL N
Sbjct: 241 SHQVMDVFLADRKLNISPAYLRPGFAFGGSCLPKDLRSLVHAAQRADVSVPILSHVLPSN 300
Query: 294 ERQPLKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYD 353
+ +EL+++ +VG+ GL+FKP TDD+RE+ + ++L +G + +D
Sbjct: 301 SAHLERAVELVER----TGKRRVGMFGLSFKPGTDDLRESPLVELAERLFGKGYDLRIHD 356
Query: 354 PKA---------MENFKRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFESLDY--- 401
E + P + + + A+S +EVL +V L+ T RD L
Sbjct: 357 ANVSLSRLLGANREYVETRLPHLAQLL--ADSVDEVLDHAEVCLVGT--RDPAVLSALPH 412
Query: 402 -SGKIVIDGRRVRSAE--KTAKIYEGVCW 427
+G ++ID + A+ +T Y G+ W
Sbjct: 413 GAGPLLIDLIHLPDADTRRTEPGYMGLAW 441
>pir||C70526 probable UDP-glucose dehydrogenase - Mycobacterium tuberculosis
(strain H37RV) >gi|2193943|emb|CAB09606.1| (Z96800) udgA
[Mycobacterium tuberculosis]
Length = 443
Score = 261 bits (661), Expect = 8e-69
Identities = 166/430 (38%), Positives = 239/430 (54%), Gaps = 32/430 (7%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQE--F 58
M S+ G+GY+G +G +LG+ V+ VD+D KV + P YE GL +L+ +
Sbjct: 1 MRCSVFGTGYLGATHAVGMAQLGHEVVGVDIDPGKVAKLAGGDIPFYEPGLRKLLTDNLA 60
Query: 59 KGKYYATNNYREAILNSDITFITVGTPSK-PDGTIDLTYVKNAAKEIGKALKEKDNFHIV 117
G+ T +Y A +D+ F+ VGTP K + DL +V + L I+
Sbjct: 61 AGRLRFTTDYDMAADFADVHFLGVGTPQKIGEYGADLRHVHAVIDALVPRLVRAS---IL 117
Query: 118 VVKSTVLPGTTEGVIRPILEKYSGKKAFQ--DFGLAMNPEFLREGVALKDFLNPDRIVIG 175
V KSTV GT L +G A + D +A NPEFLREG A+ D LNPDRIV+G
Sbjct: 118 VGKSTVPVGTAAE-----LGHRAGALAPRGVDVEIAWNPEFLREGFAVHDTLNPDRIVLG 172
Query: 176 VQDERTKK--VLEKLYEPFNA---PKLFTDIKTAEMIKYASNAFLATKISFANEIGNICK 230
VQD+ T+ + +LY P A P L TD++TAE++K ++NAFLATKISF N I +C+
Sbjct: 173 VQDDSTRAEVAVRELYAPLLAAGVPFLVTDLQTAELVKVSANAFLATKISFINAISEVCE 232
Query: 231 KLGIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPII--LKA 288
G D ++ + +G D RI +G+GFGG C PKD++A + +A ELG D + L+
Sbjct: 233 AAGADVSQLADALGYDPRIGRQCLNAGLGFGGGCLPKDIRAFMARAGELGADQALTFLRE 292
Query: 289 VLQVNERQPLKLIELLKKHV-PNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGA 347
V +N R+ K++EL +L + VLG AFKP +DDVR++ A V +L GA
Sbjct: 293 VDSINMRRRTKMVELATTACGGSLLGANIAVLGAAFKPESDDVRDSPALNVAGQLQLNGA 352
Query: 348 KVIAYDPKAMENFKRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFESLD------- 400
V YDPKA++N R +P ++YA S E D +L+LTEWR+F L+
Sbjct: 353 TVHVYDPKALDNAHRLFP----TLNYAVSVAEACERADAVLVLTEWREFIDLEPADLANR 408
Query: 401 YSGKIVIDGR 410
++++DGR
Sbjct: 409 VRARVIVDGR 418
>sp|O86422|UDG_PSEAE UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|3559950|emb|CAA09327.1| (AJ010734)
UDP-glucose 6-dehydrogenase [Pseudomonas aeruginosa]
Length = 452
Score = 241 bits (608), Expect = 1e-62
Identities = 142/342 (41%), Positives = 202/342 (58%), Gaps = 9/342 (2%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEF-- 58
M + +IG+GYVGLVT F ++GN+V V+ D +V + + PIYE GLE ++++
Sbjct: 1 MRLCVIGAGYVGLVTAACFAEMGNQVRCVERDRERVARLRRGEMPIYEPGLESILRDQLD 60
Query: 59 KGKYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVV 118
+ T + E + ++++ I VGTP DG+ DL++V A+++G L++ IVV
Sbjct: 61 AARLTFTASLAEGLADAEVVLIAVGTPCGEDGSADLSHVLAVAEQLGAQLRQAC---IVV 117
Query: 119 VKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQD 178
KSTV GT E V I + ++ +A NPEFL+EG A+ DF PDR++IG +
Sbjct: 118 NKSTVPVGTAERVEEIIRLGLARRRKRFRVAVASNPEFLKEGSAVDDFRRPDRVIIGSAE 177
Query: 179 ERTKKVLEKLYEPF---NAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGID 235
+ + L +LY PF + L + AE KYA+NAFLATKISF NE+ +C G+D
Sbjct: 178 TQAGETLRQLYAPFLRNHERVLLMGRREAEFSKYAANAFLATKISFMNEMAGLCALTGVD 237
Query: 236 SWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNER 295
V G+G D RI HF +G G+GGSCFPKD++ALI+ AE+ G D IL+AV N R
Sbjct: 238 IEDVRRGMGSDKRIGTHFIYAGCGYGGSCFPKDVRALIRSAEQQGYDSQILRAVEARNAR 297
Query: 296 QPLKLIELL-KKHVPNLKDMKVGVLGLAFKPNTDDVRETRAY 336
Q L E L + + V + GLAFKP TDD+RE RA+
Sbjct: 298 QKELLFETLGELFQGRWQGRTVALWGLAFKPGTDDLRERRAW 339
>gb|AAD44217.2|AF143772_23 (AF143772) GdhgA [Mycobacterium avium]
Length = 346
Score = 240 bits (607), Expect = 2e-62
Identities = 131/306 (42%), Positives = 188/306 (60%), Gaps = 13/306 (4%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFK- 59
+ +S++GSGYVGLVTG GN V+ VD+D+ K+ ++ PI+E GL EL+ +
Sbjct: 26 LKISVVGSGYVGLVTGACLADSGNDVVCVDIDQAKIDLLLAGGVPIFEPGLAELIARNRE 85
Query: 60 -GKYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVV 118
G T + + I ++D+ FI V TP G DLTYV + A +IG + D + ++V
Sbjct: 86 NGLIDFTTDRQRGIEHADVIFIAVPTPMGESGAADLTYVFSVADDIGSYI---DRYKVIV 142
Query: 119 VKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQD 178
KSTV GT + + I K Q+F + NPEFL++G A+ DF+ PDR+VIG
Sbjct: 143 DKSTVPVGTADQITAIIRSKTD-----QEFDVVSNPEFLKQGKAIADFMQPDRVVIGSDS 197
Query: 179 ERTKKVLEKLYEPFNA---PKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGID 235
+R +++E+LYEPF P + D+++AEM KYA+N FLATKISF NE+ N+C+K G D
Sbjct: 198 KRALRIMEELYEPFLRTFHPLIAIDVRSAEMAKYAANCFLATKISFINEMSNLCEKAGAD 257
Query: 236 SWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNER 295
V E +G D RI F GIG+GGSC PKD++AL+ A+ LG D +L+AV +VN+
Sbjct: 258 ISAVREAIGADKRIGYDFLFPGIGYGGSCLPKDVRALLYTADCLGSDMHLLRAVERVNDE 317
Query: 296 QPLKLI 301
Q L+
Sbjct: 318 QKAALV 323
>gb|AAD20371.1| (AF125999) UDP-D-glucose-dehydrogenase gdhgA [Mycobacterium avium]
Length = 346
Score = 239 bits (603), Expect = 5e-62
Identities = 130/306 (42%), Positives = 187/306 (60%), Gaps = 13/306 (4%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFK- 59
+ +S++GSGYVGLVTG GN V+ VD+D+ K+ ++ PI+E GL EL+ +
Sbjct: 26 LKISVVGSGYVGLVTGACLADSGNDVVCVDIDQAKIDLLLAGSVPIFEPGLAELIARNRE 85
Query: 60 -GKYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVV 118
G T + + I ++D+ FI V TP G DLTYV + A +IG + D + ++V
Sbjct: 86 NGLIDFTTDRQRGIEHADVIFIAVPTPMGESGAADLTYVFSVADDIGSYI---DRYKVIV 142
Query: 119 VKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQD 178
KSTV GT + + I K Q+F + NPEFL++G A+ DF+ PDR+VIG
Sbjct: 143 DKSTVPVGTADQITAIIRSKTD-----QEFDVVSNPEFLKQGKAIADFMQPDRVVIGSDS 197
Query: 179 ERTKKVLEKLYEPFNA---PKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGID 235
+R +++E+LYEPF P + D+++AEM KYA+N FLATKISF NE+ N+C+K G D
Sbjct: 198 KRALRIMEELYEPFLRTFHPLIAIDVRSAEMAKYAANCFLATKISFINEMSNLCEKAGAD 257
Query: 236 SWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNER 295
V E +G D RI F GIG+G SC PKD++AL+ A+ LG D +L+AV +VN+
Sbjct: 258 ISAVREAIGADKRIGYDFLFPGIGYGASCLPKDVRALLYTADCLGSDMHLLRAVERVNDE 317
Query: 296 QPLKLI 301
Q L+
Sbjct: 318 QKAALV 323
>sp|Q58454|YA54_METJA HYPOTHETICAL PROTEIN MJ1054 >gi|2129344|pir||E64431 UDPglucose
6-dehydrogenase (EC 1.1.1.22) (intein-containing) -
Methanococcus jannaschii >gi|1591706|gb|AAB99056.1|
(U67548) UDP-glucose dehydrogenase, putative
[Methanococcus jannaschii]
Length = 895
Score = 226 bits (569), Expect = 5e-58
Identities = 138/401 (34%), Positives = 229/401 (56%), Gaps = 36/401 (8%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
MN+S+IG+GYVGL+ +G + G V+ +D+DE KV+ +N + P+YEEGLE L+++
Sbjct: 1 MNISVIGTGYVGLIQAVGLAEFGFDVVGIDIDESKVKALNRGECPLYEEGLEGLLKKHVN 60
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVK 120
K + I +SD+ F+ VGTP DG DL ++ +A ++I + + +K+++ ++V+K
Sbjct: 61 KNLTFTTSYKPIKDSDVIFLCVGTPQDKDGNADLRFLFSAVEKIKETI-DKEDYKVIVIK 119
Query: 121 STVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDER 180
STV GT V + +L+ Y + + NPEFLREG+A+ DF NP+R+++G ++
Sbjct: 120 STVPVGTNRRV-KELLKDY-------NVDVVSNPEFLREGIAVYDFFNPERVILGFENLN 171
Query: 181 TKK---VLEKLYEPF---NAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGI 234
KK ++E++Y+ F N P + T+ +TAE+IKYASNAFLATKISF NE+ + K+
Sbjct: 172 NKKPIEIMEEVYKYFKDKNIPFVITNWETAELIKYASNAFLATKISFINELAKLSDKVKA 231
Query: 235 DSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNE 294
D + +GLD RI F +GIG+GGSCF D I + G + I K + ++ +
Sbjct: 232 DIKTISYAMGLDPRIGNKFLNAGIGYGGSCFHPDEVLFIDRGR--GLECITFKELFELED 289
Query: 295 RQPLKLIELLKKHVPNLKDMKVG--------VLGLAFKPNTDDVRETRAYIVIKKLLEEG 346
+ +K++ + + +LK +K+ ++ L F +++ T+ + V+ +LE+G
Sbjct: 290 KDNVKILSFDGEKL-SLKKLKLASKRYYNDDLITLRFNLGR-EIKITKDHPVV--ILEDG 345
Query: 347 AKVIAYDPKAMENFKRFYPDVGRQISYANSAEEVLREVDVI 387
I E K P Y N EE E+D++
Sbjct: 346 ELKIKLTSDVKEGDKVILP-------YGNFGEEREIEIDIL 379
Score = 106 bits (261), Expect = 7e-22
Identities = 73/181 (40%), Positives = 95/181 (52%), Gaps = 19/181 (10%)
Query: 263 SCFPKDLKALIKKAEELGEDPIILKAVLQVNERQPLKLIELLKKHVPNLKDMKVGVLGLA 322
+CFPKD+KALIK+ E +PI++KA VNE Q E +K + NL VLGLA
Sbjct: 714 NCFPKDVKALIKQFENNNIEPILIKATDIVNEEQIKWFFEKIKNYYGNLNGKTFAVLGLA 773
Query: 323 FKPNTDDVRETRAYIVIKKLLEEGAKVIAYD--PKAMENFKRFYP------DVGRQISYA 374
FKPNTDD+RE+RA +I LLE GA V +D KA EN Y G +
Sbjct: 774 FKPNTDDLRESRAIKLIDMLLESGAIVKGFDYVEKARENTINMYKLDKSKGFYGYNLYVL 833
Query: 375 NSAEEVLREVDVILILTEWRDFESLDY-------SGKIVIDGRRVRSAEKTAKI---YEG 424
+ E ++ VD I+I E+ DF D+ K+V DGR + EK K+ Y G
Sbjct: 834 DDLYETVKNVDGIIITVEY-DFNKEDWEKIGNLVKEKVVFDGRNILDVEKIKKLGFKYYG 892
Query: 425 V 425
V
Sbjct: 893 V 893
>pir||JC2525 UDP-glucose dehydrogenase (EC 1.1.99.-) - Xanthomonas campestris
pv. campestris >gi|747911|emb|CAA56166.1| (X79772)
UDP-glucose dehydrogenase [Xanthomonas campestris]
Length = 445
Score = 224 bits (566), Expect = 1e-57
Identities = 138/340 (40%), Positives = 191/340 (55%), Gaps = 14/340 (4%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQ--EF 58
M V+I G+GYVGLVTG ++G+ VI VD+D+ KV +N PIYE GLE +++
Sbjct: 1 MRVAIFGTGYVGLVTGTCLAEVGHHVICVDIDQAKVDGLNRGVIPIYEPGLEPMVKGNHA 60
Query: 59 KGKYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVV 118
G+ T + EAI + +ITFI VGTP DG+ DL YV A+ +G+ + D ++V
Sbjct: 61 SGRLRFTTDAAEAIAHGEITFIAVGTPPDEDGSADLQYVLAVARTVGRHI---DGPSVIV 117
Query: 119 VKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQD 178
KSTV T + V I E+ + +F + NPEFL+EG A+ D + PDRIVIG +
Sbjct: 118 NKSTVPVRTADKVRAAIQEELDARGVDHEFDVVSNPEFLKEGDAVADCMRPDRIVIGAKK 177
Query: 179 ERTKKVLEKLYEPFNAPK---LFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGID 235
+ +LY PFN + + D+++AE+ KYA+NA LATKISF NEI NI +++G D
Sbjct: 178 PAAIARMRRLYAPFNRNRDRIVEMDVRSAELTKYAANAMLATKISFMNEIANIAERVGAD 237
Query: 236 SWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNER 295
V G+G D RI HF + + K A E G P +L AV VN
Sbjct: 238 VEHVRNGIGSDPRIGWHFIYPVPATARA--SRRCAGARKTAHEYGMQPTLLNAVESVNNA 295
Query: 296 QPLKLIELLKKHVP----NLKDMKVGVLGLAFKPNTDDVR 331
Q L EL+++H ++ V GLAFKPNTDD+R
Sbjct: 296 QKGHLFELVQRHYADGNGSIAGKTFAVWGLAFKPNTDDMR 335
>gb|AAF98561.1|AC013427_4 (AC013427) Strong similarity to UDP-Glucose 6-Dehydrogenase from
Glycine max gb|6136119 and is a member of the
UDP-glucose/GDP-mannose dehydrogenase PF|00984 family.
ESTs gb|AV566422, gb|AV555903 come from this gene.
[Arabidopsis thaliana]
Length = 481
Score = 223 bits (563), Expect = 3e-57
Identities = 157/466 (33%), Positives = 242/466 (51%), Gaps = 53/466 (11%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGN---RVIFVDVDEWKVRVINNAQPPIYEEGLEELMQE 57
+ + IG+GYVG T M + L V+ VD+ E ++ N+ + PIYE GLE+++++
Sbjct: 2 VKICCIGAGYVGGPT-MAVMALKCPEIEVVVVDISEPRINAWNSDRLPIYEPGLEDVVKQ 60
Query: 58 FKGK-YYATNNYREAILNSDITFITVGTPSKPDG-----TIDLTYVKNAAKEIGKALKEK 111
+GK + + + + + SDI F++V TP+K G DLTY ++AA+ I K
Sbjct: 61 CRGKNLFFSTDVEKHVFESDIVFVSVNTPTKTQGLGAGKAADLTYWESAARMIADVSKSS 120
Query: 112 DNFHIVVVKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDR 171
IVV KSTV T E + + + G +F + NPEFL EG A+KD NPDR
Sbjct: 121 K---IVVEKSTVPVRTAEAIEKILTHNSKGI----EFQILSNPEFLAEGTAIKDLYNPDR 173
Query: 172 IVIGVQD----ERTKKVLEKLYEPFNAPK--LFTDIKTAEMIKYASNAFLATKISFANEI 225
++IG +D ++ K L +Y + + + T++ +AE+ K A+NAFLA +IS N +
Sbjct: 174 VLIGGRDTAAGQKAIKALRDVYAHWVPVEQIICTNLWSAELSKLAANAFLAQRISSVNAM 233
Query: 226 GNICKKLGIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAE--ELGEDP 283
+C+ G D +V VG D RI P F + +GFGGSCF KD+ LI E L E
Sbjct: 234 SALCEATGADVTQVAHAVGTDTRIGPKFLNASVGFGGSCFQKDILNLIYICECNGLPEAA 293
Query: 284 IILKAVLQVNERQPLKLIELLKKHVPN-LKDMKVGVLGLAFKPNTDDVRETRAYIVIKKL 342
K V++VN+ Q ++ + + N + K+ +LG AFK +T D RET A V +L
Sbjct: 294 NYWKQVVKVNDYQKIRFANRVVSSMFNTVSGKKIAILGFAFKKDTGDTRETPAIDVCNRL 353
Query: 343 LEEGAKVIAYDPKAME-------NFKRFYPD------------VGRQISYANSAEEVLRE 383
+ + AK+ YDP+ +E + RF D + Q++ + A E ++
Sbjct: 354 VADKAKLSIYDPQVLEEQIRRDLSMARFDWDHPVPLQQIKAEGISEQVNVVSDAYEATKD 413
Query: 384 VDVILILTEWRDFESLDY--------SGKIVIDGRRVRSAEKTAKI 421
+ +LTEW +F+SLD+ V DGR V A K +I
Sbjct: 414 AHGLCVLTEWDEFKSLDFKKIFDNMQKPAFVFDGRNVVDAVKLREI 459
>dbj|BAB11006.1| (AB009054) UDP-glucose dehydrogenase [Arabidopsis thaliana]
Length = 480
Score = 214 bits (540), Expect = 1e-54
Identities = 151/466 (32%), Positives = 242/466 (51%), Gaps = 54/466 (11%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKL---GNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQE 57
+ + IG+GYVG T M + L V VD+ ++ N+ Q PIYE GL++++++
Sbjct: 2 VKICCIGAGYVGGPT-MAVIALKCPDIEVAVVDISVPRINAWNSDQLPIYEPGLDDIVKQ 60
Query: 58 FKGK-YYATNNYREAILNSDITFITVGTPSKPDG-----TIDLTYVKNAAKEIGK-ALKE 110
+GK + + + + + +DI F++V TP+K G DLTY ++AA+ I ++ +
Sbjct: 61 CRGKNLFFSTDVEKHVREADIVFVSVNTPTKTTGLGAGKAADLTYWESAARMIADVSVSD 120
Query: 111 KDNFHIVVVKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPD 170
K IVV KSTV T E + + ++ G K F + NPEFL EG A+ D NPD
Sbjct: 121 K----IVVEKSTVPVKTAEAIEKILMHNSKGIK----FQILSNPEFLAEGTAIADLFNPD 172
Query: 171 RIVIGVQDE----RTKKVLEKLYEPF--NAPKLFTDIKTAEMIKYASNAFLATKISFANE 224
R++IG ++ + + L+++Y + + T++ +AE+ K A+NAFLA +IS N
Sbjct: 173 RVLIGGRETPEGFKAVQTLKEVYANWVPEGQIITTNLWSAELSKLAANAFLAQRISSVNA 232
Query: 225 IGNICKKLGIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKAL--IKKAEELGED 282
+ +C+ G D +V VG D RI F + +GFGGSCF KD+ L I + L E
Sbjct: 233 MSALCESTGADVTQVSYAVGTDSRIGSKFLNASVGFGGSCFQKDILNLVYICQCNGLPEV 292
Query: 283 PIILKAVLQVNERQPLKLIELLKKHVPN-LKDMKVGVLGLAFKPNTDDVRETRAYIVIKK 341
K V+++N+ Q + + + + N + + KV +LG AFK +T D RET A V K
Sbjct: 293 AEYWKQVIKINDYQKNRFVNRIVSSMFNTVSNKKVAILGFAFKKDTGDTRETPAIDVCKG 352
Query: 342 LLEEGAKVIAYDPKAME-------NFKRF-----------YPDVGRQISYANSAEEVLRE 383
LL + A++ YDP+ E + K+F P +Q+S A E ++
Sbjct: 353 LLGDKAQISIYDPQVTEEQIQRDLSMKKFDWDHPLHLQPMSPTTVKQVSVTWDAYEATKD 412
Query: 384 VDVILILTEWRDFESLDY--------SGKIVIDGRRVRSAEKTAKI 421
+ +LTEW +F+SLDY + DGR + + K +I
Sbjct: 413 AHAVCVLTEWDEFKSLDYQKIFDNMQKPAFIFDGRNIMNVNKLREI 458
>dbj|BAA99938.1| (AP001309) UDP-glucose dehydrogenase [Arabidopsis thaliana]
Length = 480
Score = 213 bits (537), Expect = 3e-54
Identities = 151/466 (32%), Positives = 241/466 (51%), Gaps = 54/466 (11%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKL---GNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQE 57
+ + IG+GYVG T M + L V VD+ ++ N+ PIYE GL++++++
Sbjct: 2 VKICCIGAGYVGGPT-MAVIALKCPDVEVAVVDISVPRINAWNSDTLPIYEPGLDDVVKQ 60
Query: 58 FKGK-YYATNNYREAILNSDITFITVGTPSKPDG-----TIDLTYVKNAAKEIGK-ALKE 110
+GK + + + + + +DI F++V TP+K G DLTY ++AA+ I ++ +
Sbjct: 61 CRGKNLFFSTDVEKHVREADIVFVSVNTPTKTRGLGAGKAADLTYWESAARMIADVSVSD 120
Query: 111 KDNFHIVVVKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPD 170
K IVV KSTV T E + + + G K F + NPEFL EG A+KD NPD
Sbjct: 121 K----IVVEKSTVPVKTAEAIEKILTHNSKGIK----FQILSNPEFLAEGTAIKDLFNPD 172
Query: 171 RIVIGVQDE----RTKKVLEKLYEPF--NAPKLFTDIKTAEMIKYASNAFLATKISFANE 224
R++IG ++ + + L+ +Y + + T++ +AE+ K A+NAFLA +IS N
Sbjct: 173 RVLIGGRETPEGFKAVQTLKNVYAHWVPEGQIITTNLWSAELSKLAANAFLAQRISSVNA 232
Query: 225 IGNICKKLGIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAE--ELGED 282
+ +C+ G D +V VG D RI P F S +GFGGSCF KD+ L+ E L E
Sbjct: 233 MSALCEATGADVTQVSYAVGTDSRIGPKFLNSSVGFGGSCFQKDILNLVYICECNGLPEV 292
Query: 283 PIILKAVLQVNERQPLKLIELLKKHVPN-LKDMKVGVLGLAFKPNTDDVRETRAYIVIKK 341
K V+++N+ Q + + + + N + + K+ VLG AFK +T D RET A V K
Sbjct: 293 AEYWKQVIKINDYQKSRFVNRVVSSMFNSVSNKKIAVLGFAFKKDTGDTRETPAIDVCKG 352
Query: 342 LLEEGAKVIAYDPKAME------------------NFKRFYPDVGRQISYANSAEEVLRE 383
LLE+ A++ YDP+ E + + P +Q++ A E ++
Sbjct: 353 LLEDKARLSIYDPQVTEDQIQRDLSMNKFDWDHPLHLQPMSPTTVKQVTVTWDAYEATKD 412
Query: 384 VDVILILTEWRDFESLDY--------SGKIVIDGRRVRSAEKTAKI 421
I I+TEW +F++LD+ V DGR + + +K +I
Sbjct: 413 AHGICIMTEWDEFKNLDFQKIFDNMQKPAFVFDGRNIMNLQKLREI 458
>sp|Q96558|UGDH_SOYBN UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|7431381|pir||T08818 probable UDPglucose
6-dehydrogenase (EC 1.1.1.22) - soybean
>gi|1518540|gb|AAB58398.1| (U53418) UDP-glucose
dehydrogenase [Glycine max]
Length = 480
Score = 213 bits (536), Expect = 4e-54
Identities = 150/465 (32%), Positives = 239/465 (51%), Gaps = 52/465 (11%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKL---GNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQE 57
+ + IG+GYVG T M + L V VD+ + ++ N+ Q PIYE GL+ ++++
Sbjct: 2 VKICCIGAGYVGGPT-MAVIALKCPSIEVAVVDISKSRIAAWNSDQLPIYEPGLDGVVKQ 60
Query: 58 FKGK-YYATNNYREAILNSDITFITVGTPSKPDG-----TIDLTYVKNAAKEIGKALKEK 111
+GK + + + + + +DI F++V TP+K G DLTY ++AA+ I K
Sbjct: 61 CRGKNLFFSTDVEKHVFEADIVFVSVNTPTKTQGLGAGKAADLTYWESAARMIADVSKSD 120
Query: 112 DNFHIVVVKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDR 171
IVV KSTV T E + + + G K F + NPEFL EG A+KD NPDR
Sbjct: 121 K---IVVEKSTVPVKTAEAIEKILTHNSKGIK----FQILSNPEFLAEGTAIKDLFNPDR 173
Query: 172 IVIGVQD----ERTKKVLEKLYEPFNAPK--LFTDIKTAEMIKYASNAFLATKISFANEI 225
++IG ++ ++ + L+ +Y + + L T++ +AE+ K A+NAFLA +IS N +
Sbjct: 174 VLIGGRETPEGQKAIQTLKDVYAQWVPEERILTTNLWSAELSKLAANAFLAQRISSVNAM 233
Query: 226 GNICKKLGIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAE--ELGEDP 283
+C+ G + +V VG D RI P F + +GFGGSCF KD+ L+ E L E
Sbjct: 234 SALCEATGANVQQVSYSVGTDSRIGPKFLNASVGFGGSCFQKDILNLVYICECNGLPEVA 293
Query: 284 IILKAVLQVNERQPLKLIELLKKHVPN-LKDMKVGVLGLAFKPNTDDVRETRAYIVIKKL 342
K V+++N+ Q + + + + N + + K+ +LG AFK +T D RET A V + L
Sbjct: 294 EYWKQVIKINDYQKSRFVNRVVASMFNTVSNKKIAILGFAFKKDTGDTRETPAIDVCQGL 353
Query: 343 LEEGAKVIAYDPKAME------------------NFKRFYPDVGRQISYANSAEEVLREV 384
L + A + YDP+ E + + P +++S A E ++
Sbjct: 354 LGDKANLSIYDPQVTEDQIQRDLSMNKFDWDHPIHLQPTSPTTVKKVSVVWDAYEATKDA 413
Query: 385 DVILILTEWRDFESLDY--------SGKIVIDGRRVRSAEKTAKI 421
+ ILTEW +F++LDY V DGR + A+K +I
Sbjct: 414 HGLCILTEWDEFKTLDYQKIFDNMQKPAFVFDGRNIVDADKLREI 458
>gb|AAF04455.1|AF053973_1 (AF053973) UDP-glucose dehydrogenase [Populus tremula x Populus
tremuloides]
Length = 481
Score = 211 bits (532), Expect = 1e-53
Identities = 154/467 (32%), Positives = 241/467 (50%), Gaps = 55/467 (11%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKL---GNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQE 57
+ + IG+GYVG T M + L V+ VD+ E ++ N+ Q PIYE GL ++++E
Sbjct: 2 VKICCIGAGYVGGPT-MAVIALKCPSIEVVVVDIWEPRIAAWNSDQLPIYEPGLYDVVKE 60
Query: 58 FKGK-YYATNNYREAILNSDITFITVGTPSKPDG-----TIDLTYVKNAAKEIGKALKEK 111
+G+ + + + + + +DI F++V TP+K G DLTY ++AA+ I K
Sbjct: 61 CRGRNLFFSKDVEKHVAEADIVFVSVNTPTKTQGLGAGKAADLTYWESAARTIADVSKSD 120
Query: 112 DNFHIVVVKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDR 171
IVV KSTV T E + + + G K F + NPEFL EG A+ D PDR
Sbjct: 121 K---IVVEKSTVPVKTAEAIEKILTHNSKGIK----FQILSNPEFLAEGTAIGDLFQPDR 173
Query: 172 IVIGVQD----ERTKKVLEKLYEPFNAPK---LFTDIKTAEMIKYASNAFLATKISFANE 224
++IG ++ ++ + L+ +Y + P+ L T++ +AE+ K A+NAFLA +IS N
Sbjct: 174 VLIGGRETPEGQKAIQALKDVYAHW-VPEDRILTTNLWSAELSKLAANAFLAQRISSVNA 232
Query: 225 IGNICKKLGIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAE--ELGED 282
+ +C+ G D +V VG D RI P F + +GFGGSCF KD+ L+ E L E
Sbjct: 233 MSALCEATGADVAEVSYAVGKDSRIGPKFLNASVGFGGSCFQKDILNLVYICECNGLPEV 292
Query: 283 PIILKAVLQVNERQPLKLIELLKKHVPN-LKDMKVGVLGLAFKPNTDDVRETRAYIVIKK 341
K V+++N+ Q + + + + N + K+ +LG AFK +T D RET A V +
Sbjct: 293 AEYWKQVIKINDYQKSRFVNRVVSSMFNTVSQKKIAILGFAFKKDTGDTRETPAIDVCQG 352
Query: 342 LLEEGAKVIAYDPKA----------MENFKRFYP---------DVGRQISYANSAEEVLR 382
LL + A + YDP+ M+ F +P Q++ + A E +
Sbjct: 353 LLGDKALLSIYDPQVQKEHIQRDLIMKKFDWDHPLHLQPKSASSAVEQVTVTSDAYEATK 412
Query: 383 EVDVILILTEWRDFESLDYS--------GKIVIDGRRVRSAEKTAKI 421
E + ILTEW +F++LDY+ V DGR V +A+K +I
Sbjct: 413 EAHGVCILTEWDEFKTLDYNKIYDNMQKPAFVFDGRNVVNADKLREI 459
>pir||T51527 UDP-glucose dehydrogenase-like protein - Arabidopsis thaliana
>gi|9755804|emb|CAC01748.1| (AL391143) UDP-glucose
dehydrogenase-like protein [Arabidopsis thaliana]
Length = 480
Score = 210 bits (529), Expect = 3e-53
Identities = 154/466 (33%), Positives = 239/466 (51%), Gaps = 54/466 (11%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKL---GNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQE 57
+ + IG+GYVG T M + L V VD+ ++ N+ Q PIYE GL++++++
Sbjct: 2 VKICCIGAGYVGGPT-MAVIALKCPSVEVAVVDISVPRINAWNSDQLPIYEPGLDDVVKQ 60
Query: 58 FKGK-YYATNNYREAILNSDITFITVGTPSKPDG-----TIDLTYVKNAAKEIGK-ALKE 110
+GK + + + + + +DI F++V TP+K G DLTY ++AA+ I ++ +
Sbjct: 61 CRGKNLFFSTDVEKHVREADIVFVSVNTPTKTRGLGAGKAADLTYWESAARMIADVSVSD 120
Query: 111 KDNFHIVVVKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPD 170
K IVV KSTV T E + + + G K F + NPEFL EG A++D PD
Sbjct: 121 K----IVVEKSTVPVKTAEAIEKILTHNSKGIK----FQILSNPEFLAEGTAIEDLFMPD 172
Query: 171 RIVIGVQDER----TKKVLEKLYEPFNAPK--LFTDIKTAEMIKYASNAFLATKISFANE 224
R++IG ++ K L+ +Y + + L T++ +AE+ K A+NAFLA +IS N
Sbjct: 173 RVLIGGRETTEGFAAVKALKDIYAQWVPEERILTTNLWSAELSKLAANAFLAQRISSVNA 232
Query: 225 IGNICKKLGIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAE--ELGED 282
+ +C+ G + +V VG D RI P F S +GFGGSCF KD+ L+ E L E
Sbjct: 233 MSALCEATGANVSEVSYAVGKDSRIGPKFLNSSVGFGGSCFQKDILNLVYICECNGLPEV 292
Query: 283 PIILKAVLQVNERQPLKLIELLKKHVPN-LKDMKVGVLGLAFKPNTDDVRETRAYIVIKK 341
K V+++N+ Q + + + + N + + K+ VLG AFK +T D RET A V K
Sbjct: 293 AEYWKQVIKINDYQKTRFVNRIVSSMFNTVSNKKIAVLGFAFKKDTGDTRETPAIDVCKG 352
Query: 342 LLEEGAKVIAYDPKAME------------------NFKRFYPDVGRQISYANSAEEVLRE 383
LL + A++ YDP+ E + + P +Q+S A A ++
Sbjct: 353 LLGDKARLSIYDPQVTEEQIQRDLTMNKFDWDHPLHLQPMSPTTVKQVSVAWDAYTATKD 412
Query: 384 VDVILILTEWRDFESLDY--------SGKIVIDGRRVRSAEKTAKI 421
I ILTEW +F+ LD+ V DGR V A+K +I
Sbjct: 413 AHGICILTEWDEFKKLDFQRIFENMQKPAFVFDGRNVVDADKLREI 458
>sp|O70199|UGDH_RAT UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|3133257|dbj|BAA28215.1| (AB013732)
UDP-glucose dehydrogeanse [Rattus norvegicus]
Length = 493
Score = 205 bits (515), Expect = 1e-51
Identities = 148/445 (33%), Positives = 228/445 (50%), Gaps = 42/445 (9%)
Query: 3 VSIIGSGYVGLVTGMGFVKLGN--RVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
+ IG+GYVG T ++ RV VDV+E ++ N+ PIYE GL+E+++ +G
Sbjct: 7 ICCIGAGYVGGPTCSVIARMCPEIRVTVVDVNEARINAWNSPTLPIYEPGLKEVVESCRG 66
Query: 61 K-YYATNNYREAILNSDITFITVGTPSKPDG-----TIDLTYVKNAAKEIGKALKEKDNF 114
K + + N +AI +D+ FI+V TP+K G DL Y++ A+ I ++ + +
Sbjct: 67 KNLFFSTNIDDAIREADLVFISVNTPTKTYGMGKGRAADLKYIEACARRI---VQNSNGY 123
Query: 115 HIVVVKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVI 174
IV KSTV E IR I + + K + + NPEFL EG A+KD NPDR++I
Sbjct: 124 KIVTEKSTVPVRAAES-IRRIFD--ANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLI 180
Query: 175 GVQD----ERTKKVLEKLYEPFNAPK---LFTDIKTAEMIKYASNAFLATKISFANEIGN 227
G + +R + L +YE + PK L T+ ++E+ K A+NAFLA +IS N I
Sbjct: 181 GGDETPEGQRAVQALCAVYEHW-VPKEKILTTNTWSSELSKLAANAFLAQRISSINSISA 239
Query: 228 ICKKLGIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELG--EDPII 285
+C+ G D +V +G+D RI F ++ +GFGG CF KD+ L+ E L E
Sbjct: 240 LCESTGADVEEVATAIGMDQRIGNKFLKASVGFGGGCFQKDVLNLVYLCEALNLPEVARY 299
Query: 286 LKAVLQVNERQPLKLIELLKKHVPN-LKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLE 344
+ V+ +N+ Q + + + N + D K+ +LG AFK +T D RE+ + + K L++
Sbjct: 300 WQQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMD 359
Query: 345 EGAKVIAYDPKAMEN---FKRFYP------DVGRQISYANSAEEVLREVDVILILTEWRD 395
EGA + YDPK +P V R ++ + E ++I TEW
Sbjct: 360 EGAHLHIYDPKVPREQIVVDLSHPGVSADDQVSRLVTISKDPYEACDGAHALVICTEWDM 419
Query: 396 FESLDY--------SGKIVIDGRRV 412
F+ LDY + DGRRV
Sbjct: 420 FKELDYERIHKRMLKPAFIFDGRRV 444
>gi|4507813 UDP-glucose dehydrogenase [Homo sapiens]
>gi|11435916|ref|XP_003427.1| UDP-glucose dehydrogenase
[Homo sapiens] >gi|6175086|sp|O60701|UGDH_HUMAN
UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE)
(UDP-GLCDH) (UDPGDH) >gi|3127127|gb|AAC36095.1|
(AF061016) UDP-glucose dehydrogenase [Homo sapiens]
>gi|3452405|emb|CAA07609.1| (AJ007702) UDPglucose
dehydrogenase [Homo sapiens] >gi|7025909|emb|CAB75891.1|
(AJ272274) UDP-glucose dehydrogenase [Homo sapiens]
Length = 494
Score = 204 bits (513), Expect = 2e-51
Identities = 148/445 (33%), Positives = 228/445 (50%), Gaps = 42/445 (9%)
Query: 3 VSIIGSGYVGLVTGMGFVKLGN--RVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
+ IG+GYVG T + RV VDV+E ++ N+ PIYE GL+E+++ +G
Sbjct: 7 ICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESCRG 66
Query: 61 K-YYATNNYREAILNSDITFITVGTPSKPDG-----TIDLTYVKNAAKEIGKALKEKDNF 114
K + + N +AI +D+ FI+V TP+K G DL Y++ A+ I ++ + +
Sbjct: 67 KNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRI---VQNSNGY 123
Query: 115 HIVVVKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVI 174
IV KSTV E IR I + + K + + NPEFL EG A+KD NPDR++I
Sbjct: 124 KIVTEKSTVPVRAAES-IRRIFD--ANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLI 180
Query: 175 GVQD----ERTKKVLEKLYEPFNAPK---LFTDIKTAEMIKYASNAFLATKISFANEIGN 227
G + +R + L +YE + P+ L T+ ++E+ K A+NAFLA +IS N I
Sbjct: 181 GGDETPEGQRAVQALCAVYEHW-VPREKILTTNTWSSELSKLAANAFLAQRISSINSISA 239
Query: 228 ICKKLGIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELG--EDPII 285
+C+ G D +V +G+D RI F ++ +GFGGSCF KD+ L+ E L E
Sbjct: 240 LCEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARY 299
Query: 286 LKAVLQVNERQPLKLIELLKKHVPN-LKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLE 344
+ V+ +N+ Q + + + N + D K+ +LG AFK +T D RE+ + + K L++
Sbjct: 300 WQQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMD 359
Query: 345 EGAKVIAYDPKAMEN---FKRFYP------DVGRQISYANSAEEVLREVDVILILTEWRD 395
EGA + YDPK +P V R ++ + E ++I TEW
Sbjct: 360 EGAHLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKDPYEACDGAHAVVICTEWDM 419
Query: 396 FESLDY--------SGKIVIDGRRV 412
F+ LDY + DGRRV
Sbjct: 420 FKELDYERIHKKMLKPAFIFDGRRV 444
>gi|6678499 UDP-glucose dehydrogenase [Mus musculus]
>gi|6136117|sp|O70475|UGDH_MOUSE UDP-GLUCOSE
6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|3127129|gb|AAC36096.1| (AF061017)
UDP-glucose dehydrogenase [Mus musculus]
Length = 493
Score = 204 bits (513), Expect = 2e-51
Identities = 148/445 (33%), Positives = 228/445 (50%), Gaps = 42/445 (9%)
Query: 3 VSIIGSGYVGLVTGMGFVKLGN--RVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
+ IG+GYVG T + RV VDV+E ++ N+ PIYE GL+E+++ +G
Sbjct: 7 ICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNEARINAWNSPTLPIYEPGLKEVVESCRG 66
Query: 61 K-YYATNNYREAILNSDITFITVGTPSKPDG-----TIDLTYVKNAAKEIGKALKEKDNF 114
K + + N +AI +D+ FI+V TP+K G DL Y++ A+ I ++ + +
Sbjct: 67 KNLFFSTNIDDAIREADLVFISVNTPTKTYGMGKGRAADLKYIEACARRI---VQNSNGY 123
Query: 115 HIVVVKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVI 174
IV KSTV E IR I + + K + + NPEFL EG A+KD NPDR++I
Sbjct: 124 KIVTEKSTVPVRAAES-IRRIFD--ANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLI 180
Query: 175 GVQD----ERTKKVLEKLYEPFNAPK---LFTDIKTAEMIKYASNAFLATKISFANEIGN 227
G + ++ + L +YE + PK L T+ ++E+ K A+NAFLA +IS N I
Sbjct: 181 GGDETPEGQKAVRALCAVYEHW-VPKEKILTTNTWSSELSKLAANAFLAQRISSINSISA 239
Query: 228 ICKKLGIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELG--EDPII 285
+C+ G D +V +G+D RI F ++ +GFGGSCF KD+ L+ E L E
Sbjct: 240 LCEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARY 299
Query: 286 LKAVLQVNERQPLKLIELLKKHVPN-LKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLE 344
+ V+ +N+ Q + + + N + D K+ +LG AFK +T D RE+ + + K L++
Sbjct: 300 WQQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMD 359
Query: 345 EGAKVIAYDPKAMEN---FKRFYP------DVGRQISYANSAEEVLREVDVILILTEWRD 395
EGA + YDPK +P V R ++ + E ++I TEW
Sbjct: 360 EGAHLHIYDPKVPREQIVVDLSHPGVSADDQVSRLVTISKDPYEACDGAHALVICTEWDM 419
Query: 396 FESLDY--------SGKIVIDGRRV 412
F+ LDY + DGRRV
Sbjct: 420 FKELDYERIHKKMLKPAFIFDGRRV 444
>sp|O02373|UGDH_DROME UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) (SUGARLESS PROTEIN) >gi|2149991|gb|AAB58714.1|
(AF000570) UDP-glucose dehydrogenase [Drosophila
melanogaster] >gi|2257994|gb|AAB63208.1| (AF007870)
UDP-glucose dehydrogenase [Drosophila melanogaster]
>gi|2266945|gb|AAB63462.1| (AF009013)
UDP-glucose-6-dehydrogenase [Drosophila melanogaster]
>gi|7295310|gb|AAF50631.1| (AE003560) sgl gene product
[Drosophila melanogaster]
Length = 476
Score = 201 bits (507), Expect = 1e-50
Identities = 153/457 (33%), Positives = 235/457 (50%), Gaps = 43/457 (9%)
Query: 1 MNVSIIGSGYVGLVT-GMGFVKLGNRVI-FVDVDEWKVRVINNAQPPIYEEGLEELMQEF 58
M V IG+GYVG T + +K + VI VD ++ N+ + PIYE GL+E++++
Sbjct: 1 MKVCCIGAGYVGGPTCAVMALKCPDIVITLVDKSSERIAQWNSDKLPIYEPGLDEVVKKC 60
Query: 59 KG-KYYATNNYREAILNSDITFITVGTPSKPDGT-----IDLTYVKNAAKEIGKALKEKD 112
+ + + + AI +D+ FI+V TP+K G DL YV++AA+ I + +
Sbjct: 61 RNVNLFFSTDIETAIKEADLIFISVNTPTKTCGNGKGRAADLKYVESAARMIAEIAQSNK 120
Query: 113 NFHIVVVKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRI 172
IVV KSTV E ++ + + +K + + NPEFL EG A+ D LN DR+
Sbjct: 121 ---IVVEKSTVPVRAAESIMHILR---ANQKPGIHYDILSNPEFLAEGTAINDLLNADRV 174
Query: 173 VIGVQDE-RTKKVLEKL---YEPFNAPK---LFTDIKTAEMIKYASNAFLATKISFANEI 225
+IG ++ + +EKL YE + PK L T+ ++E+ K A+NAFLA +IS N +
Sbjct: 175 LIGGEETPEGHQAVEKLSWIYEHW-IPKQNILTTNTWSSELSKLAANAFLAQRISSINSL 233
Query: 226 GNICKKLGIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELG--EDP 283
+C+ G D +V VGLD RI F ++ +GFGGSCF KD+ LI E L E
Sbjct: 234 SAVCEATGADVSEVARAVGLDSRIGSKFLQASVGFGGSCFQKDILNLIYICENLNLPEVA 293
Query: 284 IILKAVLQVNERQPLKLIELLKKHVPN-LKDMKVGVLGLAFKPNTDDVRETRAYIVIKKL 342
+ V+ +NE Q + + + + + N + D ++ +LG AFK NT D RET A V + L
Sbjct: 294 AYWQQVIDMNEYQKRRFSQKIIESLFNTVSDKRIAILGFAFKKNTGDTRETAAITVCQTL 353
Query: 343 LEEGAKVIAYDPKAMEN---FKRFYPDVGRQISYANSAEEV-------LREVDVILILTE 392
LEEGA + YDPK +P V A ++ +R ++I TE
Sbjct: 354 LEEGAALDIYDPKVEPEQIIDDLTHPSVTESPEKVKKAVQIHSDPYSAVRATHALVICTE 413
Query: 393 WRDFESLDY--------SGKIVIDGRRVRSAEKTAKI 421
W +F LD+ + DGR++ E+ +I
Sbjct: 414 WDEFVDLDFKRIYQSMMKPAYIFDGRKILDHERLQQI 450
>gb|AAC97125.1| (AF001310) UDP-glucose dehydrogenase [Drosophila melanogaster]
Length = 476
Score = 201 bits (506), Expect = 1e-50
Identities = 153/457 (33%), Positives = 234/457 (50%), Gaps = 43/457 (9%)
Query: 1 MNVSIIGSGYVGLVT-GMGFVKLGNRVI-FVDVDEWKVRVINNAQPPIYEEGLEELMQEF 58
M V IG+GYVG T + +K + VI VD ++ N+ + PIYE GL+E+++
Sbjct: 1 MKVCCIGAGYVGGPTCAVMALKCPDIVITLVDKSSERIAQWNSDKLPIYEPGLDEVVKRC 60
Query: 59 KG-KYYATNNYREAILNSDITFITVGTPSKPDGT-----IDLTYVKNAAKEIGKALKEKD 112
+ + + + AI +D+ FI+V TP+K G DL YV++AA+ I + +
Sbjct: 61 RNVNLFFSTDIETAIKEADLIFISVNTPTKTCGNGKGRAADLKYVESAARMIAEIAQSNK 120
Query: 113 NFHIVVVKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRI 172
IVV KSTV E ++ + + +K + + NPEFL EG A+ D LN DR+
Sbjct: 121 ---IVVEKSTVPVRAAESIMHILR---ANQKPGIHYDILSNPEFLAEGTAINDLLNADRV 174
Query: 173 VIGVQDE-RTKKVLEKL---YEPFNAPK---LFTDIKTAEMIKYASNAFLATKISFANEI 225
+IG ++ + +EKL YE + PK L T+ ++E+ K A+NAFLA +IS N +
Sbjct: 175 LIGGEETPEGHQAVEKLSWIYEHW-IPKQNILTTNTWSSELSKLAANAFLAQRISSINSL 233
Query: 226 GNICKKLGIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELG--EDP 283
+C+ G D +V VGLD RI F ++ +GFGGSCF KD+ LI E L E
Sbjct: 234 SAVCEATGADVSEVARAVGLDSRIGSKFLQASVGFGGSCFQKDILNLIYICENLNLPEVA 293
Query: 284 IILKAVLQVNERQPLKLIELLKKHVPN-LKDMKVGVLGLAFKPNTDDVRETRAYIVIKKL 342
+ V+ +NE Q + + + + + N + D ++ +LG AFK NT D RET A V + L
Sbjct: 294 AYWQQVIDMNEYQKRRFSQKIIESLFNTVSDKRIAILGFAFKKNTGDTRETAAITVCQTL 353
Query: 343 LEEGAKVIAYDPKAMEN---FKRFYPDVGRQISYANSAEEV-------LREVDVILILTE 392
LEEGA + YDPK +P V A ++ +R ++I TE
Sbjct: 354 LEEGAALDIYDPKVEPEQIIDDLTHPSVTESPEKVKKAVQIHSDPYSAVRATHALVICTE 413
Query: 393 WRDFESLDY--------SGKIVIDGRRVRSAEKTAKI 421
W +F LD+ + DGR++ E+ +I
Sbjct: 414 WDEFVDLDFKRIYQSMMKPAYIFDGRKILDHERLQQI 450
>sp|P12378|UGDH_BOVIN UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|3747091|gb|AAC64183.1| (AF095792)
UDP-glucose dehydrogenase [Bos taurus]
Length = 494
Score = 201 bits (506), Expect = 1e-50
Identities = 146/445 (32%), Positives = 226/445 (49%), Gaps = 42/445 (9%)
Query: 3 VSIIGSGYVGLVTGMGFVKLGN--RVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
+ IG+GYVG T + RV VD++E ++ N+ PIYE GL+E+++ +G
Sbjct: 7 ICCIGAGYVGGPTCSVIAHMCPEIRVTVVDINESRINAWNSPTLPIYEPGLKEVVESCRG 66
Query: 61 K-YYATNNYREAILNSDITFITVGTPSKPDG-----TIDLTYVKNAAKEIGKALKEKDNF 114
K + + N +AI +D+ FI+V TP+K G DL Y++ A+ I ++ +
Sbjct: 67 KNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRI---VQNSHGY 123
Query: 115 HIVVVKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVI 174
IV KSTV E IR I + + K + + NPEFL EG A+KD NPDR++I
Sbjct: 124 KIVTEKSTVPVRAAES-IRRIFD--ANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLI 180
Query: 175 GVQD----ERTKKVLEKLYEPFNAPK---LFTDIKTAEMIKYASNAFLATKISFANEIGN 227
G + +R + L +YE + P+ L T+ ++E+ K +NAFLA +IS N I
Sbjct: 181 GGDETPEGQRAVQALCAVYEHW-VPREKILTTNTWSSELSKLTANAFLAQRISSINSISA 239
Query: 228 ICKKLGIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELG--EDPII 285
+C+ G D +V +G+D RI F ++ +GFGGSCF KD+ L+ E L E
Sbjct: 240 LCEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARY 299
Query: 286 LKAVLQVNERQPLKLIELLKKHVPN-LKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLE 344
+ V+ +N+ Q + + + N + D K+ +LG AFK +T D RE+ + + K L++
Sbjct: 300 WQQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMD 359
Query: 345 EGAKVIAYDPKAMEN---FKRFYP------DVGRQISYANSAEEVLREVDVILILTEWRD 395
EGA + YDPK +P V R ++ + E ++I TEW
Sbjct: 360 EGAHLHIYDPKVPREQIVVDLSHPGVSKDDQVARLVTISKDPYEACDGAHAVVICTEWDM 419
Query: 396 FESLDY--------SGKIVIDGRRV 412
F+ LDY + DGRRV
Sbjct: 420 FKELDYERIHKKMLKPAFIFDGRRV 444
>pir||JE0353 uridine diphosphoglucose dehydrogenase (EC 1.-.-.-) - human
Length = 494
Score = 200 bits (503), Expect = 3e-50
Identities = 147/445 (33%), Positives = 226/445 (50%), Gaps = 42/445 (9%)
Query: 3 VSIIGSGYVGLVTGMGFVKLGN--RVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
+ IG+GYVG T + RV DV+E ++ N+ PIYE GL+E+++ +G
Sbjct: 7 ICCIGAGYVGGPTCSVIAHMCPEIRVTRRDVNESRINAWNSPTLPIYEPGLKEVVESCRG 66
Query: 61 K-YYATNNYREAILNSDITFITVGTPSKPDG-----TIDLTYVKNAAKEIGKALKEKDNF 114
K + + N +AI +D+ FI+V TP+K G DL Y++ A+ I ++ + +
Sbjct: 67 KNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRI---VQNSNGY 123
Query: 115 HIVVVKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVI 174
IV KSTV E IR I + + K + + NPEFL EG A+KD NPDR++I
Sbjct: 124 KIVTEKSTVPVRAAES-IRRIFD--ANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLI 180
Query: 175 GVQD----ERTKKVLEKLYEPFNAPK---LFTDIKTAEMIKYASNAFLATKISFANEIGN 227
G + +R + L +YE P+ L T+ ++E+ K A+NAFLA +IS N I
Sbjct: 181 GGDETPEGQRAVQALCAVYE-HEVPRERILTTNTWSSELSKLAANAFLAQRISSINSISA 239
Query: 228 ICKKLGIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELG--EDPII 285
+C+ G D +V +G+D RI F ++ +GFGGSCF KD+ L+ E L E
Sbjct: 240 LCEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARY 299
Query: 286 LKAVLQVNERQPLKLIELLKKHVPN-LKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLE 344
+ V+ +N+ Q + + + N + D K+ +LG AFK +T D RE+ + + K L++
Sbjct: 300 WQQVIDMNDYQRRRFASRIIDALFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMD 359
Query: 345 EGAKVIAYDPKAMEN---FKRFYP------DVGRQISYANSAEEVLREVDVILILTEWRD 395
EGA + YDPK +P V R ++ + E ++I TEW
Sbjct: 360 EGAHLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKDPYEACDGAHAVVICTEWDM 419
Query: 396 FESLDY--------SGKIVIDGRRV 412
F+ LDY + DGRRV
Sbjct: 420 FKELDYERIHKKMLKPAFIFDGRRV 444
>pir||E69211 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase -
Methanobacterium thermoautotrophicum (strain Delta H)
>gi|2621926|gb|AAB85334.1| (AE000860)
UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase
[Methanobacterium thermoautotrophicum]
Length = 431
Score = 199 bits (501), Expect = 5e-50
Identities = 139/426 (32%), Positives = 217/426 (50%), Gaps = 25/426 (5%)
Query: 3 VSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEF--KG 60
+++ G G++GL T F + G +V VD++ V +N + P+ E GL+EL+ E G
Sbjct: 6 IAVFGLGHIGLPTAALFARAGFKVTGVDINPETVEKVNIGRSPVLEPGLDELVAEVVGTG 65
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVK 120
AT + A S++ I V TP + T DL+ V +AA+ I + LK+ D +V+V+
Sbjct: 66 NLGATMDGERAAAESEVMIIVVPTPVNSENTSDLSAVISAAETISRGLKKGD---LVIVE 122
Query: 121 STVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDER 180
STV PG + V+ PILEK +G K +DFGLA PE L + N R++ G E
Sbjct: 123 STVPPGACQNVVLPILEK-TGLKVSEDFGLAYTPERALPNNTLHEMQNNARVIGGADPES 181
Query: 181 TKKVLEKLYEPFNAPKLFT--DIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSWK 238
++ LY + ++ D+ TAEM+K N + T I+ ANE+ IC+ LGID+
Sbjct: 182 ARRAAA-LYRRITSGEVIVVDDLMTAEMVKLMENTYRDTNIALANELAVICEALGIDAIN 240
Query: 239 VFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQPL 298
E R++ H G G GG C D +++ AE G +++ +VNE PL
Sbjct: 241 AIEAANHHPRVNIH--TPGPGVGGHCLSIDPYFIVEMAERKGVPARLIRTAREVNESMPL 298
Query: 299 KLIELLKKHVPN----LKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDP 354
++E++++ + + LK VG+LG+A+K + D RET ++ LL EGA+V+ DP
Sbjct: 299 HVLEIVRETLESRGKTLKGSNVGILGVAYKGDVADARETPTRPLVAALLSEGARVLVNDP 358
Query: 355 KAMENFKRFYPDVGRQISYAN-SAEEVLREVDVILIL--TEWRDFESLDYSGKIVIDGRR 411
P++ R + S EE L V+L+ TE+ + G I I R
Sbjct: 359 HVS-------PEIIRGMGVEPVSLEEALNSDCVVLMTDHTEYLEITPEMIPGGIFICTRP 411
Query: 412 VRSAEK 417
V E+
Sbjct: 412 VMDPER 417
>pir||A54926 UDPglucose 6-dehydrogenase (EC 1.1.1.22) - bovine
>gi|806944|gb|AAB32227.1| UDP-glucose dehydrogenase,
UDPGDH=52 kda subunit {EC 1.1.1.22} [cattle, liver,
Peptide, 468 aa]
Length = 468
Score = 198 bits (499), Expect = 8e-50
Identities = 144/445 (32%), Positives = 221/445 (49%), Gaps = 43/445 (9%)
Query: 3 VSIIGSGYVGLVTGMGFVKLGN--RVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
+ IG+GYVG T + RV VD++E ++ N+ PIYE GL+E+++ +G
Sbjct: 7 ICCIGAGYVGGPTCSVIAHMCPEIRVTVVDINESRINAWNSPTLPIYEPGLKEVVESCRG 66
Query: 61 K-YYATNNYREAILNSDITFITVGTPSKPDG-----TIDLTYVKNAAKEIGKALKEKDNF 114
K + + N +AI +D+ FI+V TP+K G DL Y++ A+ I ++ +
Sbjct: 67 KNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRI---VQNSHGY 123
Query: 115 HIVVVKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVI 174
IV KSTV E + R Q NPEFL EG A+KD NPDR++I
Sbjct: 124 KIVTEKSTVPVRAAESIRRIFDANTKPNLNLQ----VSNPEFLAEGTAIKDLKNPDRVLI 179
Query: 175 GVQD----ERTKKVLEKLYEPFNAPK---LFTDIKTAEMIKYASNAFLATKISFANEIGN 227
G + +R + L +YE + P+ L T+ ++E+ K +NAFLA +IS N I
Sbjct: 180 GGDETPEGQRAVQALCAVYEHW-VPREKILTTNTWSSELSKLTANAFLAQRISSINSISA 238
Query: 228 ICKKLGIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELG--EDPII 285
+C+ G D +V +G+D RI F ++ +GFGGSCF KD+ L+ E L E
Sbjct: 239 LCEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARY 298
Query: 286 LKAVLQVNERQPLKLIELLKKHVPN-LKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLE 344
+ V+ +N+ Q + + + N + D K+ +LG AFK +T D RE+ + + K L++
Sbjct: 299 WQQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMD 358
Query: 345 EGAKVIAYDPKAMEN---FKRFYP------DVGRQISYANSAEEVLREVDVILILTEWRD 395
EGA + YDPK +P V R ++ + E ++I TEW
Sbjct: 359 EGAHLHIYDPKVPREQIVVDLSHPGVSKDDQVARLVTISKDPYEACDGAHAVVICTEWDM 418
Query: 396 FESLDY--------SGKIVIDGRRV 412
F+ LDY + DGRRV
Sbjct: 419 FKELDYERIHKKMLKPAFIFDGRRV 443
>sp|Q19905|UGDH_CAEEL PROBABLE UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE)
(UDP-GLCDH) (UDPGDH) >gi|7500161|pir||T21550
hypothetical protein F29F11.1 - Caenorhabditis elegans
>gi|3876536|emb|CAA98269.1| (Z73974) Similarity to
Xanthomonas UDP-glucose dehydrogenase (TR:G747911),
contains similarity to Pfam domain: PF00984
(UDP-glucose/GDP-mannose dehydrogenase family),
Score=750.5, E-value=2.3e-222, N=1 [Caenorhabditis
elegans]
Length = 481
Score = 196 bits (492), Expect = 6e-49
Identities = 147/453 (32%), Positives = 232/453 (50%), Gaps = 50/453 (11%)
Query: 3 VSIIGSGYVGLVTGMGFVKLGNR-----VIFVDVDEWKVRVINNAQPPIYEEGLEELMQE 57
V +G+GYVG G + ++ V VD++ K+ N+ + PIYE GL+E++
Sbjct: 12 VVCVGAGYVG---GPTCAMIAHKCPHITVTVVDMNTAKIAEWNSDKLPIYEPGLDEIVFA 68
Query: 58 FKGK-YYATNNYREAILNSDITFITVGTPSKPDG-----TIDLTYVKNAAKEIGKALKEK 111
+G+ + +++ +AI +D+ FI+V TP+K G DL YV++ ++ I +
Sbjct: 69 ARGRNLFFSSDIPKAIAEADLIFISVNTPTKMYGRGKGMAPDLKYVESVSRTIAQYAGGP 128
Query: 112 DNFHIVVVKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDR 171
IVV KSTV E I IL + F + NPEFL EG A+KD NPDR
Sbjct: 129 K---IVVEKSTVPVKAAES-IGCILREAQKNNENLKFQVLSNPEFLAEGTAMKDLANPDR 184
Query: 172 IVIGVQD--ERTKKVLE--KLYEPFNAPK---LFTDIKTAEMIKYASNAFLATKISFANE 224
++IG + E + V E ++YE + P+ + T+ ++E+ K +NAFLA +IS N
Sbjct: 185 VLIGGESSPEGLQAVAELVRIYENW-VPRNRIITTNTWSSELSKLVANAFLAQRISSINS 243
Query: 225 IGNICKKLGIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPI 284
I +C+ G + +V VG D RI F ++ +GFGGSCF KD+ +L+ E L +
Sbjct: 244 ISAVCEATGAEISEVAHAVGYDTRIGSKFLQASVGFGGSCFQKDVLSLVYLCESLNLPQV 303
Query: 285 --ILKAVLQVNERQPLKLIELLKKHVPN-LKDMKVGVLGLAFKPNTDDVRETRAYIVIKK 341
+ V+ +N Q + + + + N + D K+ + G AFK NT D RE+ A VIK
Sbjct: 304 ADYWQGVININNWQRRRFADKIIAELFNTVTDKKIAIFGFAFKKNTGDTRESSAIHVIKH 363
Query: 342 LLEEGAKVIAYDPKAMEN-------FKRFYPDVGRQISYANSAEEVLREVDVILILTEWR 394
L+EE AK+ YDPK ++ DV R I+ + R I++LTEW
Sbjct: 364 LMEEHAKLSVYDPKVQKSQMLNDLASVTSAQDVERLITVESDPYAAARGAHAIVVLTEWD 423
Query: 395 DFESLDYS--------------GKIVIDGRRVR 413
+F L+YS G++++D + +R
Sbjct: 424 EFVELNYSQIHNDMQHPAAIFDGRLILDQKALR 456
>pir||G75173 udp-n-acetyl-d-mannosaminuronic acid dehydrogenase PAB0378 -
Pyrococcus abyssi (strain Orsay)
>gi|5457980|emb|CAB49470.1| (AJ248284)
UDP-N-ACETYL-D-MANNOSAMINURONIC ACID DEHYDROGENASE
[Pyrococcus abyssi]
Length = 418
Score = 189 bits (476), Expect = 4e-47
Identities = 145/443 (32%), Positives = 223/443 (49%), Gaps = 48/443 (10%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEF-- 58
M +++IG GY+GL T + F G+ VI D+ V +N I E + E ++E
Sbjct: 1 MRIAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVEPEIGERLREVVS 60
Query: 59 KGKYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVV 118
KGK AT++Y + + +D I V TP +G DLTY+++A K I K ++++ +VV
Sbjct: 61 KGKLRATSDYND-LKGADAFIICVQTPLS-NGVPDLTYLESAIKTIAKVIEKE---ALVV 115
Query: 119 VKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQD 178
++STV PGTTE + + +LE+ +G K +DF +A PE + G K+ + RI+ GV
Sbjct: 116 IESTVPPGTTERMAK-LLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYNSRIIGGV-S 173
Query: 179 ERTKKVLEKLYEPFNAPKLF-TDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSW 237
E+ + EKLY F ++F T TAEM+K N F I+ ANE + K G++ +
Sbjct: 174 EKASILAEKLYRSFVKGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVY 233
Query: 238 KVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQP 297
+ E R+ H R GIG GG C PKD L+ + ED +++ ++NE P
Sbjct: 234 EAIELANTHPRVKIH--RPGIGVGGHCLPKDPYLLLANVD---EDLGLIRKARKINESMP 288
Query: 298 ----LKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYD 353
L E L + + D V VLGLA+K +TDDVR + A IK + ++ +V YD
Sbjct: 289 RFAAKLLFEALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYD 348
Query: 354 PKAMENFKRFYPDVGRQISYANSA----EEVLREVDVILILTEWRDFESLDYS------- 402
P Y N EE ++ VD I+I T+ F +++
Sbjct: 349 P------------------YVNGTHTILEEAVKGVDAIIIATDHSMFREIEWDKLGNLMR 390
Query: 403 GKIVIDGRRVRSAEKTAKIYEGV 425
KI+IDGR + I++G+
Sbjct: 391 NKIIIDGRNLVKEPPKGFIFKGI 413
>pir||F71153 probable Vi polysaccharide biosynthesis protein - Pyrococcus
horikoshii >gi|3256832|dbj|BAA29515.1| (AP000002) 455aa
long hypothetical Vi polysaccharide biosynthesis protein
[Pyrococcus horikoshii]
Length = 455
Score = 184 bits (463), Expect = 1e-45
Identities = 137/434 (31%), Positives = 212/434 (48%), Gaps = 48/434 (11%)
Query: 3 VSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKGKY 62
+ I+G GYVGL + F K N VI D++ K+ + + Y E + + E
Sbjct: 20 IGIVGLGYVGLPLAVAFSKKFN-VIGYDINTKKIDSLKKRKS--YIEDVRD--DEINLNR 74
Query: 63 YATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVKST 122
N E + D ITV TP + D T DL+YVK+AA+ +G+ L+ V+++ST
Sbjct: 75 LQPTNDPEDLKKCDFIIITVPTPLREDKTPDLSYVKDAARTVGRILRRGQ---FVILEST 131
Query: 123 VLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDERTK 182
PGTTE V+ PILE+ SG K +DFG+A +PE + G N ++V G+ E T+
Sbjct: 132 TYPGTTEEVLIPILEEESGLKVIEDFGVAYSPERIDPGNKRYKIENTPKVVGGLTPEFTE 191
Query: 183 -------KVLEKLYEPFNAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGID 235
V+EK+ D KTAE +K N F I+ NE+ I +K+GID
Sbjct: 192 LASMLYGSVIEKIVP-------VKDCKTAEAVKMLENVFRNVNIALVNELALIFEKMGID 244
Query: 236 SWKVFEGVGLDHRISPHFFRS---GIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQV 292
W+V E + P+ F + G G GG C P D L +A++ G P ++ ++
Sbjct: 245 IWEVIEAA----KTKPYGFMAFYPGPGVGGHCIPVDPYYLSYRAKQFGIIPRFIETAGEI 300
Query: 293 NERQPLKLIEL----LKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAK 348
N P+ + L L+K ++ KV VLGLA+K + D RE+ A +I++L+E GA+
Sbjct: 301 NNYMPVHTVNLAETGLRKIGRKIRGAKVAVLGLAYKADISDTRESPAIKIIEELIERGAQ 360
Query: 349 VIAYDPKAMENFKRFYPDVGRQISYANSAEEVLREVDVILILTEWRDF-----ESLDYSG 403
V YDP +F + E++L+ D ++ +T+ F E L G
Sbjct: 361 VKVYDPYVKSVRTKF-----GTFRVTETLEDILKWSDCVIFVTDHSLFKEKMEEILKIFG 415
Query: 404 -----KIVIDGRRV 412
K+++D R +
Sbjct: 416 ETSTKKVIVDSRNI 429
>pir||F75096 udp-n-acetyl-d-mannosaminuronic acid dehydrogenase PAB0776 -
Pyrococcus abyssi (strain Orsay)
>gi|5458587|emb|CAB50075.1| (AJ248286)
UDP-N-ACETYL-D-MANNOSAMINURONIC ACID DEHYDROGENASE
[Pyrococcus abyssi]
Length = 448
Score = 181 bits (455), Expect = 1e-44
Identities = 141/445 (31%), Positives = 230/445 (51%), Gaps = 40/445 (8%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEE-GLEELMQEF- 58
+ +++ G G +GL F G +VI VD++E V +NN + I EE GL+EL+++
Sbjct: 21 VTIAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNV 80
Query: 59 -KGKYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIV 117
G+ AT + A +D+ I V T + G + L V + A++I K L++ D IV
Sbjct: 81 EAGRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGD---IV 137
Query: 118 VVKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQ 177
+ ++T+ PGTTE +I PILEK SG K DFGLA PE G A++D ++G
Sbjct: 138 ITEATMPPGTTESLI-PILEK-SGLK-LGDFGLAHAPERTMTGTAIRDITGQYPKIVGAS 194
Query: 178 DERTKKVLEKLYEPFNAPKL--FTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGID 235
DERT + + +YE N + + IK AE +K + I+ ANE+ C++ G+D
Sbjct: 195 DERTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLD 254
Query: 236 SWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNER 295
+ ++F H G G GG C P +I A++ + +++ ++N+
Sbjct: 255 AIEIFNAANTQPYC--HLHMPGAGVGGHCIPIYPWFVINLAKK--TNVRLIRTAREINDS 310
Query: 296 QPLKLIELLKKHVPN----LKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIA 351
P ++EL + + + +K K+ VLGL F+ + ++ A VI++L E GA+V A
Sbjct: 311 MPRHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYA 370
Query: 352 YDPK-AMENFKRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFESLDYS-------G 403
YDP E+ +RF +E ++VD I+I+T+ R+F++LD
Sbjct: 371 YDPLCTREDAERF----------GAKWKEDFKDVDAIVIVTDHREFKTLDLKEIAAEVRT 420
Query: 404 KIVIDGRRV---RSAEKTAKIYEGV 425
K+++DGR V A+K IY+GV
Sbjct: 421 KVIVDGRNVIHPEEAKKLGFIYKGV 445
>dbj|BAB07427.1| (AP001519) nucleotide sugar dehydrogenase [Bacillus halodurans]
Length = 388
Score = 176 bits (441), Expect = 5e-43
Identities = 123/397 (30%), Positives = 201/397 (49%), Gaps = 35/397 (8%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
MN++I G+GYVGL + + N VI D+ + KV +INN + PI + +EE + +
Sbjct: 1 MNITIAGTGYVGLSNAV-LLAQHNDVIAYDIVQEKVDMINNRKSPIVDREIEEFLATKEL 59
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVK 120
AT + +A D F+ + TP+ D + + I L N ++V+K
Sbjct: 60 NLTATTDKEKAF--KDAQFVVISTPTNYDPEKNYFDTSSVEAVISDVLSINPNA-VMVIK 116
Query: 121 STVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDER 180
ST+ G T R + E+++ K + +PEFLREG AL D L+P RIV+G + +R
Sbjct: 117 STIPVGYT----REVNERFNTKN------IIFSPEFLREGSALYDNLHPSRIVVGERTQR 166
Query: 181 TKKVLEKLYEPF---NAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSW 237
K L + N LFTD AE IK +N +LA +++F NE+ + + G+D+
Sbjct: 167 AKIFAALLVQGAIKENIDVLFTDSTEAEAIKLFANTYLAMRVAFFNELDSYAELKGLDAK 226
Query: 238 KVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQP 297
++ +GVGLD RI H+ G+GG C PKD K L+ E++ + I+ A++ N+ +
Sbjct: 227 QIIDGVGLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANFEDVPNN--IIGAIVDANDTRK 284
Query: 298 LKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDP--- 354
+ ++ K P + VG+ L K +D+ R++ V+ +L GA+V+ Y+P
Sbjct: 285 DHVANMILKREPKV----VGIYRLTMKTGSDNFRQSAILDVMTRLNNAGAEVVVYEPALD 340
Query: 355 -------KAMENFKRFYPDVGRQISYANSAEEVLREV 384
K +E+F F + AN + L+EV
Sbjct: 341 ATEFDGSKVIEDFAEF--KKMSDVIVANRLSDDLKEV 375
>pir||B71041 probable UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase -
Pyrococcus horikoshii >gi|3258047|dbj|BAA30730.1|
(AP000006) 418aa long hypothetical
UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase
[Pyrococcus horikoshii]
Length = 418
Score = 175 bits (438), Expect = 1e-42
Identities = 130/439 (29%), Positives = 214/439 (48%), Gaps = 40/439 (9%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFK- 59
M ++++G GY+GL T + F G V+ D+ ++ IN+ I E ++ ++E
Sbjct: 1 MRIAVLGLGYIGLPTAIMFASSGYDVVGYDIRSEVIKKINSGVAHIIEPEIDRRLKEVLS 60
Query: 60 -GKYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVV 118
GK T+ E + S++ I V TP D DL+Y++ A + + + + D +V+
Sbjct: 61 LGKLKVTDRV-EDLKGSNVFIICVQTPLSGDDP-DLSYLERAIRTVAEVM---DRGALVI 115
Query: 119 VKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQD 178
++ST+ PGTTE + R +LE +G + DF +A PE + G K+ + RI+ GV
Sbjct: 116 IESTIPPGTTEKMAR-LLENLTGLREGVDFYVAHAPERVMPGRIFKELVYNSRIIGGVS- 173
Query: 179 ERTKKVLEKLYEPFNAPKLF-TDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSW 237
E+ + EKLY F ++F T+ TAEM+K N F I+ ANE + + G++ +
Sbjct: 174 EKAANLAEKLYRSFVKGRIFLTNATTAEMVKLMENTFRDVNIALANEFALLAHQYGVNVY 233
Query: 238 KVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQP 297
+ E R+ H GIG GG C PKD L+ A+ ED +++ ++NER P
Sbjct: 234 EAIELANTHPRVKIH--TPGIGVGGHCLPKDPYLLLSNAK---EDFGLIRIARRINERMP 288
Query: 298 L----KLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYD 353
L E L+K + + VLGLA+K TDD R + A ++ + +V YD
Sbjct: 289 AFAAGLLFEALEKANIKPSEAIIAVLGLAYKGGTDDTRNSPALKFVEIIRNSVKEVRTYD 348
Query: 354 PKAMENFKRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFESLDYSG-------KIV 406
P +S E+V+ D I+I T+ +F+S+++ KI+
Sbjct: 349 PYVRGTH--------------DSLEKVVEGADAIVIATDHPEFKSVNWESIGKSMRHKII 394
Query: 407 IDGRRVRSAEKTAKIYEGV 425
IDGR + I+ G+
Sbjct: 395 IDGRNIIKEPPVGFIFRGI 413
>dbj|BAA77737.1| (AB008676) UDP-glucose-6-dehydrogenase [Escherichia coli]
>gi|11464509|gb|AAG35214.1| (AF176356)
UDP-glucose-6-dehydrogenase [Escherichia coli]
Length = 388
Score = 174 bits (437), Expect = 2e-42
Identities = 108/362 (29%), Positives = 196/362 (53%), Gaps = 23/362 (6%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
M ++I G+GYVGL G+ + + V+ +D+ +V ++N+ PI ++ +++ +Q K
Sbjct: 1 MKITISGTGYVGLSNGL-LIAQNHEVVALDILPSRVAMLNDRISPIVDKEIQQFLQSDKI 59
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVK 120
+ AT + EA ++D ++ + TP+ D + + ++ + + K + E + + ++V+K
Sbjct: 60 HFNATLDKNEAYRDAD--YVIIATPTDYDPKTNY-FNTSSVESVIKDVVEINPYAVMVIK 116
Query: 121 STVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDER 180
STV G TE + K ++ + +PEFLREG AL D L+P RIVIG + ER
Sbjct: 117 STVPVGFTEAM----------HKKYRTENIIFSPEFLREGKALYDNLHPSRIVIGERSER 166
Query: 181 TKKVLEKLYEPF---NAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSW 237
++ L E N P LFTD AE IK +N +LA ++++ NE+ + + LG++S
Sbjct: 167 AERFAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLNSR 226
Query: 238 KVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQP 297
++ EGV LD RI H+ G+GG C PKD K L+ + + + ++ A++ N +
Sbjct: 227 QIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNN--LISAIVDANRTRK 284
Query: 298 LKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDPKAM 357
+ + + + K VG+ L K +D+ R + ++K++ +G +VI Y+P
Sbjct: 285 ----DFIADAILSRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVIIYEPVMK 340
Query: 358 EN 359
E+
Sbjct: 341 ED 342
>pir||A81290 probable UDPglucose 6-dehydrogenase (EC 1.1.1.22) Cj1441c
[imported] - Campylobacter jejuni (strain NCTC 11168)
>gi|6968870|emb|CAB73865.1| (AL139078) putative
UDP-glucose 6-dehydrogenase [Campylobacter jejuni]
Length = 393
Score = 174 bits (437), Expect = 2e-42
Identities = 117/367 (31%), Positives = 191/367 (51%), Gaps = 31/367 (8%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLG-NRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFK 59
M + I+G GYVGL + F K N V+ +D+DE K++ INN + PI ++ +E+ +
Sbjct: 1 MKIVIVGIGYVGLANAILFSKNNENEVVLLDIDENKIQSINNHKSPIKDKLIEKFFVQNI 60
Query: 60 GKYYATNNYREAILNSDITFITVGTPSKPDGTI---DLTYVKNAAKEIGKALKEKDNFHI 116
K +AT+N +EA N+D F + TP+ D + D ++N K+I K + K N
Sbjct: 61 SKLHATSNIKEAYFNAD--FAVIATPTDYDEQLNFFDTRSIENVLKDI-KNINSKIN--- 114
Query: 117 VVVKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGV 176
V++KSTV G T+ + K+ F + +PEFLREG AL D L P RI+IG
Sbjct: 115 VIIKSTVPIGYTKTI----------KQKFNMSNIVFSPEFLREGSALYDSLYPSRIIIGD 164
Query: 177 QDERTKKVLE---KLYEPFNAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLG 233
+ K + + K E N + D AE +K SN +LA ++ F NE+ + +K
Sbjct: 165 KSVLGKTIGDLFLKNIEKKNVDIFYMDSDEAESVKLFSNTYLAMRVGFFNEVDSYARKHN 224
Query: 234 IDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVN 293
++S + +G+ D RI ++ G+GG C PKD K L+ + ++KA+++ N
Sbjct: 225 LNSADIIKGISADDRIGKYYNNPSFGYGGYCLPKDTKQLLANFYNIPNS--LIKAIVETN 282
Query: 294 ERQPLKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKV--IA 351
E + + +L+ + PN+ +G+ L K N+D+ R + +IK L E + + I
Sbjct: 283 EIRKKFITQLILEKKPNI----LGIYRLIMKQNSDNFRNSVIIDIIKYLQEYNSNIELII 338
Query: 352 YDPKAME 358
Y+P E
Sbjct: 339 YEPLVKE 345
>gb|AAG35229.1| (AF176369) UDP-glucose-6-dehydrogenase [Escherichia coli]
Length = 388
Score = 173 bits (434), Expect = 3e-42
Identities = 107/362 (29%), Positives = 196/362 (53%), Gaps = 23/362 (6%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
M ++I G+GYVGL G+ + + V+ +D+ +V ++N+ PI ++ +++ +Q K
Sbjct: 1 MKITISGTGYVGLSNGL-LIAQNHEVVALDILPSRVAMLNDRISPIVDKEIQQFLQSDKI 59
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVK 120
+ AT + EA ++D ++ + TP+ D + + ++ + + K + E + + ++V+K
Sbjct: 60 HFNATLDKNEAYRDAD--YVIIATPTDYDPKTNY-FNTSSVESVIKDVVEINPYAVMVIK 116
Query: 121 STVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDER 180
STV G TE + K ++ + +PEFLREG AL D L+P RIVIG + ER
Sbjct: 117 STVPVGFTEAM----------HKKYRTENIIFSPEFLREGKALYDNLHPSRIVIGERSER 166
Query: 181 TKKVLEKLYEPF---NAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSW 237
++ L E N P LFTD AE IK +N +LA ++++ NE+ + + LG+++
Sbjct: 167 AERFAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLNTR 226
Query: 238 KVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQP 297
++ EGV LD RI H+ G+GG C PKD K L+ + + + ++ A++ N +
Sbjct: 227 QIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNN--LISAIVDANRTRK 284
Query: 298 LKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDPKAM 357
+ + + + K VG+ L K +D+ R + ++K++ +G +VI Y+P
Sbjct: 285 ----DFIADAILSRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVIIYEPVMK 340
Query: 358 EN 359
E+
Sbjct: 341 ED 342
>sp|P76373|UDG_ECOLI UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|7431378|pir||C64968 hypothetical protein
b2028 - Escherichia coli (strain K-12)
>gi|1736716|dbj|BAA15868.1| (D90841) UDG protein.
[Escherichia coli] >gi|1788340|gb|AAC75089.1| (AE000294)
UDP-glucose 6-dehydrogenase [Escherichia coli K12]
Length = 388
Score = 172 bits (431), Expect = 8e-42
Identities = 107/362 (29%), Positives = 195/362 (53%), Gaps = 23/362 (6%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
M ++I G+GYVGL G+ + + V+ +D+ +V ++N+ PI ++ +++ +Q K
Sbjct: 1 MKITISGTGYVGLSNGL-LIAQNHEVVALDILPSRVAMLNDRISPIVDKEIQQFLQSDKI 59
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVK 120
+ AT + EA ++D ++ + TP+ D + + ++ + + K + E + + ++V+K
Sbjct: 60 HFNATLDKNEAYRDAD--YVIIATPTDYDPKTNY-FNTSSVESVIKDVVEINPYAVMVIK 116
Query: 121 STVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDER 180
STV G T + K ++ + +PEFLREG AL D L+P RIVIG + ER
Sbjct: 117 STVPVGFTAAM----------HKKYRTENIIFSPEFLREGKALYDNLHPSRIVIGERSER 166
Query: 181 TKKVLEKLYEPF---NAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSW 237
++ L E N P LFTD AE IK +N +LA ++++ NE+ + + LG++S
Sbjct: 167 AERFAALLQEGAIKQNIPMLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLNSR 226
Query: 238 KVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQP 297
++ EGV LD RI H+ G+GG C PKD K L+ + + + ++ A++ N +
Sbjct: 227 QIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNN--LISAIVDANRTRK 284
Query: 298 LKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDPKAM 357
+ + + + K VG+ L K +D+ R + ++K++ +G +VI Y+P
Sbjct: 285 ----DFIADAILSRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVIIYEPVMK 340
Query: 358 EN 359
E+
Sbjct: 341 ED 342
>sp|Q57871|Y428_METJA HYPOTHETICAL PROTEIN MJ0428 >gi|2129342|pir||D64353
UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase
homolog - Methanococcus jannaschii
>gi|1591131|gb|AAB98413.1| (U67494)
UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase
[Methanococcus jannaschii]
Length = 427
Score = 170 bits (426), Expect = 3e-41
Identities = 127/430 (29%), Positives = 224/430 (51%), Gaps = 49/430 (11%)
Query: 3 VSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKGKY 62
+ +IG GY+GL T G VI VD++E +V+ I ++ ++LM KG
Sbjct: 13 ICVIGLGYIGLPTASMLAIQGFDVIGVDINEKRVKEIKELS---FKTTEKDLMTLVKGAI 69
Query: 63 YATN-NYREAILNSDITFITVGTPS-KPDGT--IDLTYVKNAAKEIGKALKEKDNFHIVV 118
+ N + +D+ I V TP + DG DLTY+ A + I L +N ++++
Sbjct: 70 NSGNLKVQTKPEKADVFIICVPTPCIECDGEKKCDLTYLNKAIESIKPYL---ENGNLII 126
Query: 119 VKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQD 178
++ST+ PGTT+ + + + + KK + +A PE + G LK+ + DR++ GV D
Sbjct: 127 IESTIPPGTTDDIYKKLSKD---KKIY----VAHCPERVLPGSILKELVENDRVIGGV-D 178
Query: 179 ERTKKVLEKLYEPFNAPKLF-TDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSW 237
E++ ++ +++YE F K++ TD KTAEM+K N + I+ ANE I +++GI+ W
Sbjct: 179 EKSAEMAKEIYETFVTGKIYLTDAKTAEMVKLMENTYRDVNIALANEFAKIAEEIGINVW 238
Query: 238 KVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQP 297
+ E R+ + + G G GG C D +++K+ ++ +++ ++N+ P
Sbjct: 239 EAIELANKHPRV--NILKPGPGVGGHCISIDPWFIVEKS----KNAKLIRTARELNDSMP 292
Query: 298 LKLIELLKKHVPNLKDM-KVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDPKA 356
L ++E +KK + KD+ KV + G+ +K N DD RE+ A V+ KL++EG +V YD A
Sbjct: 293 LFVVEKIKKIIK--KDIGKVAIFGVTYKGNVDDTRESPAEKVVSKLIDEGFEVKCYDKYA 350
Query: 357 MENFKRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFESLD----------YSGKIV 406
+ YP NS +E + D+I+IL E ++++ D KI+
Sbjct: 351 RD---FIYP--------LNSLDEAVEGADIIVILAEHDEYKNFDKEDIKNIASKVKNKII 399
Query: 407 IDGRRVRSAE 416
+D + + + E
Sbjct: 400 LDTKNILNRE 409
>sp|O33952|UDG8_ECOLI UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|2586097|gb|AAC45829.1| (U78086)
hypothetical uridine-5'-diphosphoglucose dehydrogenase
[Escherichia coli]
Length = 388
Score = 170 bits (426), Expect = 3e-41
Identities = 107/362 (29%), Positives = 193/362 (52%), Gaps = 23/362 (6%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
M ++I G+GYVGL G+ + + V+ +D+ + KV ++N Q PI ++ +EE +
Sbjct: 1 MKITISGTGYVGLSNGI-LIAQNHEVVALDIVQAKVDMLNKKQSPIVDKEIEEYLATKDL 59
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVK 120
+ AT + +A N+D ++ + TP+ D + + ++ + + + + E + ++V+K
Sbjct: 60 NFRATTDKYDAYKNAD--YVIIATPTDYDPKTNY-FNTSSVEAVIRDVTEINPNAVMVIK 116
Query: 121 STVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDER 180
ST+ G T+ + K+ L +PEFLREG AL D L+P RIVIG + ER
Sbjct: 117 STIPVGFTKSI----------KERLGIDNLIFSPEFLREGKALYDNLHPSRIVIGERSER 166
Query: 181 TKKVLEKLYEPF---NAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSW 237
++ L E N P LFTD AE IK +N +LA ++++ NE+ + + LG+++
Sbjct: 167 AERFAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLNTR 226
Query: 238 KVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQP 297
++ EGV LD RI H+ G+GG C PKD K L+ + + + ++ A++ N +
Sbjct: 227 QIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNN--LISAIVDANRTRK 284
Query: 298 LKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDPKAM 357
+ + + + K VG+ L K +D+ R + ++K++ +G +VI Y+P
Sbjct: 285 ----DFIADAILSRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVIIYEPVMK 340
Query: 358 EN 359
E+
Sbjct: 341 ED 342
>gb|AAD50493.1|AF172324_11 (AF172324) UDP-Glc-6-dehydrogenase Ugd [Escherichia coli]
Length = 388
Score = 170 bits (426), Expect = 3e-41
Identities = 115/391 (29%), Positives = 206/391 (52%), Gaps = 30/391 (7%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
M ++I G+GYVGL G+ + + V+ +D+ + KV ++N Q PI ++ +EE +
Sbjct: 1 MKITISGTGYVGLSNGI-LIAQNHEVVALDIVQAKVDMLNKKQSPIVDKEIEEYLATKDL 59
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVK 120
+ AT + +A N+D ++ + TP+ D + + ++ + + + + E + ++++K
Sbjct: 60 NFRATTDKYDAYKNAD--YVIIATPTDYDPKTNY-FNTSSVEAVIRDVTEINPNAVMIIK 116
Query: 121 STVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDER 180
ST+ G TE + K+ F + +PEFLREG AL D L+P RIVIG Q +R
Sbjct: 117 STIPVGFTESI----------KERFGIENVIFSPEFLREGKALYDNLHPSRIVIGEQSDR 166
Query: 181 TKKVLEKLYEPF---NAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSW 237
++ L E + P LFTD AE IK +N +LA ++++ NE+ + + LG++S
Sbjct: 167 AERFAALLQEGAIKQDIPILFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLNSR 226
Query: 238 KVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQP 297
++ EGV LD RI H+ G+GG C PKD K L+ + + + ++ A++ N +
Sbjct: 227 QIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNN--LISAIVDANRTRK 284
Query: 298 LKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDPKAM 357
+ + + P + VGV L K +D++R + ++K++ + VI Y+P AM
Sbjct: 285 DFIADSILARKPKV----VGVYRLIMKSGSDNIRASSIQGIMKRIKAKCVPVIVYEP-AM 339
Query: 358 ENFKRFYPDVGRQISYANSAEEVLREVDVIL 388
+ F V R + + ++E DVI+
Sbjct: 340 KEDDFFRSRVVRDL------DAFVQEADVII 364
>pir||S70888 nucleotide sugar dehydrogenase homolog - Vibrio cholerae
>gi|1230584|gb|AAC46249.1| (U47057) nucleotide sugar
dehydrogenase [Vibrio cholerae O139]
>gi|3724323|dbj|BAA33612.1| (AB012956) probable
nucleotide sugar dehydrogenase [Vibrio cholerae]
>gi|1588978|prf||2209416H nucleotide sugar dehydrogenase
[Vibrio cholerae]
Length = 388
Score = 169 bits (425), Expect = 4e-41
Identities = 111/360 (30%), Positives = 188/360 (51%), Gaps = 29/360 (8%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
M +++ G+GYVGL M + ++VI VD+ KV ++NN Q PI ++ +E +
Sbjct: 1 MKIAVAGTGYVGLSNAM-LLAQHHQVIAVDIIAEKVAMLNNKQSPIVDQEIEYFLAHKTL 59
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPD---GTIDLTYVKNAAKEIGKALKEKDNFHIV 117
+ AT + + A N+D F+ + TP+ D + T V++ KE+ + ++
Sbjct: 60 DFQATLDKQSAYRNAD--FVIIATPTDYDPQTNYFNTTSVESVIKEVMAINPQA----VM 113
Query: 118 VVKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQ 177
V+KSTV G T + K+ + +PEFLREG AL D L+P RI++G +
Sbjct: 114 VIKSTVPVGYTARI----------KEQLGCDNILFSPEFLREGKALHDNLHPSRIIVGER 163
Query: 178 DERTKKVLEKLYEPF---NAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGI 234
ER + L E N P LFTD AE +K SN +LA ++++ NE+ + + G+
Sbjct: 164 SERAEVFANLLVEGAVKKNIPVLFTDSTEAEAVKLFSNTYLAMRVAYFNELDSYAEAHGL 223
Query: 235 DSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNE 294
D+ ++ EGVGLD RI H+ G+GG C PKD K L+ + + I+ A+++ N
Sbjct: 224 DARQIIEGVGLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYSSVPNN--IIGAIVEANR 281
Query: 295 RQPLKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDP 354
+ + + + K P + VG+ L K +D+ R + ++K++ +G +V+ Y+P
Sbjct: 282 TRKDFVADSIIKRQPKV----VGIYRLIMKAGSDNFRASSIQGIMKRIKAKGIEVVVYEP 337
>pir||T44338 hypothetical protein wbfV [imported] - Vibrio cholerae
>gi|3721692|dbj|BAA33642.1| (AB012957) probable
nucleotide sugar dehydrogenase [Vibrio cholerae]
Length = 388
Score = 166 bits (417), Expect = 3e-40
Identities = 110/360 (30%), Positives = 186/360 (51%), Gaps = 29/360 (8%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
M +++ G+GYVGL + + ++VI VD+ KV ++NN Q PI ++ +E +
Sbjct: 1 MKIAVAGTGYVGLSNAI-LLAQHHQVIAVDIIAEKVAMLNNKQSPIVDQEIEYFLAHKTL 59
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPD---GTIDLTYVKNAAKEIGKALKEKDNFHIV 117
+ AT + + A ++D F+ + TP+ D + T V++ KE+ + ++
Sbjct: 60 DFQATLDKQSAYRDAD--FVIIATPTDYDPQTNYFNTTSVESVIKEVMAINPQA----VM 113
Query: 118 VVKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQ 177
V+KSTV G T + K + +PEFLREG AL D L+P RI++G +
Sbjct: 114 VIKSTVPVGYTVRI----------KNQLGCDNILFSPEFLREGKALHDNLHPSRIIVGER 163
Query: 178 DERTKKVLEKLYEPF---NAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGI 234
ER K L E N P LFTD AE +K SN +LA ++++ NE+ + + G+
Sbjct: 164 SERAKVFANLLVEGAVKKNIPVLFTDSTEAEAVKLFSNTYLAMRVAYFNELDSYAEAHGL 223
Query: 235 DSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNE 294
D+ ++ EGVGLD RI H+ G+GG C PKD K L+ + I+ A+++ N
Sbjct: 224 DARQIIEGVGLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYSSVPNS--IIGAIVEANR 281
Query: 295 RQPLKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDP 354
+ + + + K P + VG+ L K +D+ R + ++K++ +G +V+ Y+P
Sbjct: 282 TRKDFVADSIIKRQPKV----VGIYRLIMKAGSDNFRASSIQGIMKRIKAKGIEVVVYEP 337
>emb|CAB43615.1| (AJ239004) uridine diphosphate glucose dehydrogenase [Streptococcus
pneumoniae]
Length = 412
Score = 165 bits (414), Expect = 8e-40
Identities = 122/420 (29%), Positives = 208/420 (49%), Gaps = 53/420 (12%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
M +++ G+GYVGL + + ++VI VD+ KV +IN + PI ++ +E+ + E
Sbjct: 1 MKIAVTGTGYVGLSIAV-LLAQHHQVIAVDIIPEKVELINQRKSPIQDDYIEKYLAEKDL 59
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVK 120
AT + +EA ++D F+ + P+ D + + +A + + + + + + I+V+K
Sbjct: 60 NLVATLDAKEAYKDAD--FVVIAAPTNYDPKKNF-FDTSAVESVIETVLKYNPDAIMVIK 116
Query: 121 STVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQ--D 178
STV G TE S +K FQ + +PEFLRE AL D L P RI++G +
Sbjct: 117 STVPVGYTE----------SARKKFQTENILFSPEFLRESKALYDNLYPSRIILGTDKNN 166
Query: 179 ERTKKVLEKLYEPFNAPKLFTDIKT-------AEMIKYASNAFLATKISFANEIGNICKK 231
ER V E L DI T AE +K +N +LA ++S+ NE+ +
Sbjct: 167 ERLVSVAETFAGLLQEGALKEDIDTLYMGFTEAEAVKLFANTYLALRVSYFNELDTYSEM 226
Query: 232 LGIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQ 291
G+D+ + +GVGLD RI H+ G+GG C PKD K L+ E++ E+ ++ A+++
Sbjct: 227 KGLDTQAIIDGVGLDPRIGSHYNNPSFGYGGYCLPKDTKQLLANYEDVPEE--LIGAIVR 284
Query: 292 VNER-------QPLKLIELLKKHVPNL------KDMKVGVLGLAFKPNTDDVRETRAYIV 338
N Q LK+++ N+ KD+ +G+ L K N+D+ R++ +
Sbjct: 285 SNSTRKDFIADQVLKMVDSYDYSAHNVFNERVEKDIIIGIYRLTMKSNSDNFRQSSIQGI 344
Query: 339 IKKLLEEGAKVIAYDP--------------KAMENFKRFYPDVGRQISYANSAEEVLREV 384
+K++ +G +V+ Y+P +E FKR + Y NS E+V +V
Sbjct: 345 MKRIKAKGVRVVIYEPTLESGSTFFGSSIINDLEEFKRLSNAIVAN-RYDNSLEDVKEKV 403
>sp|Q45410|EPSD_BURSO NDP-N-ACETYL-D-GALACTOSAMINURONIC ACID DEHYDROGENASE
>gi|7449841|pir||S77638 probable
UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase (EC
1.1.1.-) - Pseudomonas solanacearum
>gi|600868|gb|AAA91627.1| (U17898) EpsD [Ralstonia
solanacearum]
Length = 423
Score = 163 bits (408), Expect = 4e-39
Identities = 126/431 (29%), Positives = 212/431 (48%), Gaps = 34/431 (7%)
Query: 3 VSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKGKY 62
+S++G GY+GL T +I VD+++ V IN A+ I E L+ L++ +
Sbjct: 12 ISVVGLGYIGLPTATVLASRQRELIGVDINQHAVDTINQARIHIVEPDLDMLVRAAVSQG 71
Query: 63 Y--ATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVK 120
Y AT A D I V TP D DLTY++ AAK I LK D +VV++
Sbjct: 72 YLRATTEPEPA----DAFLIAVPTPFLEDKQPDLTYIEAAAKAIAPVLKRGD---LVVLE 124
Query: 121 STVLPGTTEGVIRPILEKYS--------GKKAFQDFGLAMNPEFLREGVALKDFLNPDRI 172
ST G TE + + E+ S G+++ D +A PE + G L++ + DRI
Sbjct: 125 STSPVGATEQLSAWLSEQRSDLSFPHQLGEES--DIRVAHCPERVLPGHVLRELVENDRI 182
Query: 173 VIGVQDERTKKVLEKLYEPFNAPK-LFTDIKTAEMIKYASNAFLATKISFANEIGNICKK 231
IG R + ++LYE F + + TD +TAEM K NAF I+FANE+ IC +
Sbjct: 183 -IGGMTPRCSQAAQRLYELFVRGRCIVTDARTAEMCKLTENAFRDVNIAFANELSMICDE 241
Query: 232 LGIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQ 291
+G++ W++ R+ + + G G GG C D ++ A E +++ +
Sbjct: 242 IGVNVWELISVANRHPRV--NILQPGPGVGGHCIAVDPWFIVDAAPESAR---LIRTARE 296
Query: 292 VNERQPLKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIA 351
VN+ +P +++ +K+ K+ + GL+FK N DD+RE+ A +++ ++++ +
Sbjct: 297 VNDAKPHYVLDRVKQAARRFKEPVIACFGLSFKANIDDLRESPAIEIVRTMVQQQLGTVL 356
Query: 352 YDPKAMENFKRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFESLD---YSGKIVID 408
+E + P + N AE L D++++L + + F LD ++VID
Sbjct: 357 ----VVEPHIKVLPASLEGVELLN-AEPALSRADIVVLLVDHQKFRKLDTDRLQSRVVID 411
Query: 409 GRRVRSAEKTA 419
R + SA++ A
Sbjct: 412 TRGMWSAKRLA 422
>sp|Q47329|UDG5_ECOLI UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|2126103|pir||S70197 UDP-glucose
dehydrogenase - Escherichia coli
>gi|735963|emb|CAA54708.1| (X77617) UDP-glucose
dehydrogenase [Escherichia coli]
Length = 392
Score = 163 bits (408), Expect = 4e-39
Identities = 107/357 (29%), Positives = 189/357 (51%), Gaps = 23/357 (6%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
+ +++ G+GYVGL G+ + + V+ D + KV ++N+ PI ++ +E +
Sbjct: 5 LKITVSGAGYVGLSNGI-LMAQNHEVVAFDTHQKKVDLLNDKLSPIEDKEIENYLSTKIL 63
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVK 120
+ AT N EA N++ ++ + TP+ D + + ++ + + + + E + I+VVK
Sbjct: 64 NFRATTNKYEAYKNAN--YVIIATPTNYDPGSNY-FDTSSVEAVIRDVTEINPNAIMVVK 120
Query: 121 STVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDER 180
STV G T+ + K+ + +PEFLREG AL D L+P RI+IG ER
Sbjct: 121 STVPVGFTKTI----------KEHLGINNIIFSPEFLREGRALYDNLHPSRIIIGECSER 170
Query: 181 TKKVLEKLYEPF---NAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSW 237
+++ E N P LFTD AE IK SN +LA +++F NE+ + + G+++
Sbjct: 171 AERLAVLFQEGAIKQNIPVLFTDSTEAEAIKLFSNTYLAMRVAFFNELDSYAESFGLNTR 230
Query: 238 KVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQP 297
++ +GV LD RI ++ G+GG C PKD K L+ + + ++ A++ N +
Sbjct: 231 QIIDGVCLDPRIGNYYNNPSFGYGGYCLPKDTKQLLANYQSVPNK--LISAIVDANRTRK 288
Query: 298 LKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDP 354
+ ++ KH P + VGV L K +D+ R++ +IK++ ++G KVI Y+P
Sbjct: 289 DFITNVILKHRPQV----VGVYRLIMKSGSDNFRDSSILGIIKRIKKKGVKVIIYEP 341
>emb|CAB05929.1| (Z83335) uridine diphosphate glucose dehydrogenase [Streptococcus
pneumoniae]
Length = 410
Score = 163 bits (408), Expect = 4e-39
Identities = 119/416 (28%), Positives = 208/416 (49%), Gaps = 51/416 (12%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
M +++ G+GYVGL + + ++V+ VD+ KV +IN + PI ++ +E+ + E +
Sbjct: 1 MKIAVAGTGYVGLFIAI-LLAQHHQVVAVDIIPEKVELINKKKSPIQDDYIEKYLAEKEL 59
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVK 120
+ AT N EA N+D FI + P+ D + + ++ + + +A+ + + I+++K
Sbjct: 60 NFVATLNAEEAYENAD--FIVIAAPTNYDPKKNF-FDTSSVEAVIEAVMKYNPDAIIIIK 116
Query: 121 STVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDER 180
STV G T+ V R L + +PEFLRE AL D L P RI+IG ++
Sbjct: 117 STVPVGYTKSVRRKFLTD----------NIMFSPEFLRESKALYDNLYPSRIIIGT--DK 164
Query: 181 TKKVLEKLYEPF-----------NAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNIC 229
K L K E F N L+ D AE +K +N +LA ++S+ NE+
Sbjct: 165 DDKDLVKSAEIFVKMLQEGAVKENIETLYMDFTEAEAVKLFANTYLALRVSYFNELDTYS 224
Query: 230 KKLGIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAV 289
+ G+D+ + +GV LD RI H+ G+GG C PKD K L+ ++ ++ ++ A+
Sbjct: 225 EMKGLDTQAIIDGVCLDPRIGSHYNNPSFGYGGYCLPKDTKQLLANYSDVPQE--MITAI 282
Query: 290 LQVNERQ----PLKLIELLKKHVPN-------LKDMKVGVLGLAFKPNTDDVRETRAYIV 338
+Q N + ++++L +V N K++ VG+ L K N+D+ R++ +
Sbjct: 283 VQSNRTRKDYIADRILDLAGSYVGNDFYKPDKEKEIVVGIYRLTMKSNSDNFRQSSIQGI 342
Query: 339 IKKLLEEGAKVIAYDPKAMENFKRFYPD----------VGRQISYANSAEEVLREV 384
+K+L +G +I Y+P +E+ FY Q+ AN +E L +V
Sbjct: 343 MKRLKAKGVTIIIYEP-TLESGTTFYGSQVVNDFEIFKKSSQVIVANRFDETLEDV 397
>pir||H72358 lipopolysaccharide biosynthesis protein - Thermotoga maritima
(strain MSB8) >gi|4981101|gb|AAD35668.1|AE001733_5
(AE001733) lipopolysaccharide biosynthesis protein
[Thermotoga maritima]
Length = 434
Score = 163 bits (408), Expect = 4e-39
Identities = 133/426 (31%), Positives = 215/426 (50%), Gaps = 34/426 (7%)
Query: 3 VSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQP---PIYEEGLEELMQEFK 59
+ +IG GYVGL + K G RV+ D+ + +V ++N + + +E L++L++ K
Sbjct: 13 LGVIGLGYVGLPLAVEKAKAGYRVLGFDIQKKRVDMVNRGENYIGDVVDEDLKDLVE--K 70
Query: 60 GKYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVV 119
G AT ++ E + N D+ I V TP DLTYV N AKEI K L + +VV+
Sbjct: 71 GMIRATTDFSE-MKNCDVVTICVPTPLGKYKEPDLTYVINTAKEIAKYLHRE---MLVVL 126
Query: 120 KSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDE 179
+ST PGTTE V+ PILE +G K +DF LA +PE + G + N ++V GV ++
Sbjct: 127 ESTTYPGTTEEVVLPILES-TGLKVGKDFYLAFSPERVDPGNKIYKTKNTPKVVGGVTEK 185
Query: 180 RTKKVLEKLYEPFNAPKLFT--DIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSW 237
T+ + + LYE + T + AEM K N F IS NE+ + +++GI+ W
Sbjct: 186 CTE-LAKILYENVLEAPVHTVSSPRAAEMAKVLENTFRLVNISLINEVAIVARRMGINIW 244
Query: 238 KVFEGVGL-DHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQ 296
+V + P F G G GG C P D L KA+E +++ ++N+
Sbjct: 245 EVIDAAATKPFGFMP--FYPGPGAGGHCIPIDPFYLAYKAKEYDVRLDLVEMAGEINDFM 302
Query: 297 P----LKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAY 352
P +++ ++L + L KV +LG+A+K + DD RE+ A V L ++ A V +
Sbjct: 303 PEYVVMRVQDILNERKKPLNGSKVLLLGVAYKGDIDDTRESPALKVWDHLEKKKAVVEFF 362
Query: 353 DPKAMENFKRFYPDVGRQISY---ANSAEEVLREVDVILILTEWR---DFESLDYSGKIV 406
DP + P+V R EE L+ VD+++I T + D++ + + +V
Sbjct: 363 DP--------YVPEVKRGDRIHRRVELTEEYLKGVDIVVITTAHKNGVDYDFVVKNAPVV 414
Query: 407 IDGRRV 412
D + +
Sbjct: 415 FDTKNI 420
>sp|Q04873|UDG_SALTY UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|485529|pir||S33671 hypothetical protein
(cld 3' region) - Salmonella choleraesuis
>gi|46959|emb|CAA78945.1| (Z17278) putative
UDP-D-glucose dehydrogenase [Salmonella enterica]
Length = 388
Score = 162 bits (405), Expect = 9e-39
Identities = 103/362 (28%), Positives = 193/362 (52%), Gaps = 23/362 (6%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
M ++I G+GYVGL G+ + + V+ +D+ +V ++N+ PI ++ +++ ++E
Sbjct: 1 MKITISGTGYVGLSNGL-LIAQHHDVVALDIVPSRVELLNDRISPIVDKEIQQFLKEDNI 59
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVK 120
++ AT + +A N+D ++ + TP+ D + + ++ + + + + + ++++K
Sbjct: 60 RFRATLDKFDAYQNAD--YVIIATPTDYDPKTNY-FNTSSVESVMQDVISINPAAVMIIK 116
Query: 121 STVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDER 180
STV G T + ++ F + +PEFLREG AL D L P RIVIG Q ER
Sbjct: 117 STVPVGFTAAM----------RQKFATENIIFSPEFLREGKALYDNLYPSRIVIGEQSER 166
Query: 181 TKKVLEKLYEPF---NAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSW 237
++ L E P LFTD AE IK +N +LA ++++ NE+ + + LG+++
Sbjct: 167 AREFAALLQEGAIKQEIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAETLGLNTR 226
Query: 238 KVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQP 297
++ EGV LD RI H+ G+GG C PKD K L+ + + + I+ A+++ N +
Sbjct: 227 QIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNN--IISAIVEANRTRK 284
Query: 298 LKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDPKAM 357
+ + + P + VG+ L K +D+ R + ++K++ +G +VI Y+P
Sbjct: 285 DFIADAILARKPKV----VGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVIIYEPVME 340
Query: 358 EN 359
E+
Sbjct: 341 ED 342
>gb|AAC45348.1| (U90519) putative UDP-glucose dehydrogenase [Escherichia coli]
Length = 388
Score = 161 bits (404), Expect = 1e-38
Identities = 105/362 (29%), Positives = 188/362 (51%), Gaps = 23/362 (6%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
M ++I G+GYVGL G+ + + V+ +D+ + KV ++N PI ++ ++E + E
Sbjct: 1 MKITISGTGYVGLSNGV-LIAQNHEVVALDIVQAKVDMLNQKISPIVDKEIQEYLAEKPL 59
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVK 120
+ AT + +A N+D ++ + TP+ D + + + + + + + E + ++++K
Sbjct: 60 NFRATTDKHDAYRNAD--YVIIATPTDYDPKTNY-FNTSTVEAVIRDVTEINPNAVMIIK 116
Query: 121 STVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDER 180
ST+ G T + K+ + +PEFLREG AL D L+P RIVIG + R
Sbjct: 117 STIPVGFTRDI----------KERLGIDNVIFSPEFLREGRALYDNLHPSRIVIGERSAR 166
Query: 181 TKKVLEKLYEPF---NAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSW 237
++ + L E + P LFTD AE IK +N +LA ++++ NE+ + + G++S
Sbjct: 167 AERFADLLKEGAIKQDIPTLFTDSTEAEAIKLFANTYLALRVAYFNELDSYAESQGLNSK 226
Query: 238 KVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQP 297
++ EGV LD RI H+ G+GG C PKD K L+ E + + I+ A++ N +
Sbjct: 227 QIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYESVPNN--IIAAIVDANRTRK 284
Query: 298 LKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDPKAM 357
+ + + K VGV L K +D+ R + ++K++ +G VI Y+P
Sbjct: 285 ----DFISDSILARKPKVVGVYRLIMKSGSDNFRASSIQGIMKRIKAKGIPVIIYEPVMQ 340
Query: 358 EN 359
E+
Sbjct: 341 ED 342
>gb|AAD10180.1| (AF026471) Cps2K [Streptococcus pneumoniae]
Length = 412
Score = 161 bits (404), Expect = 1e-38
Identities = 119/421 (28%), Positives = 204/421 (48%), Gaps = 55/421 (13%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
M +++ G+GYVGL + + ++V+ VD+ KV +IN + PI ++ +E+ + +
Sbjct: 1 MKIAVAGTGYVGLSIAV-LLSQQHQVMAVDIIPEKVELINQRKSPIQDDYIEKYLAKKDL 59
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVK 120
AT + +EA ++D F+ + P+ D + I ALK + I+V+K
Sbjct: 60 NLVATLDAKEAYQDAD--FVVIAAPTNYDPKKNFFDTSAVESVIETALKYNPDA-IMVIK 116
Query: 121 STVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDER 180
STV G TE S +K FQ + +PEFLRE AL D L P RI++G
Sbjct: 117 STVPVGYTE----------SARKKFQTENILFSPEFLRESKALYDNLYPSRIILGTDKNN 166
Query: 181 TK---------KVLEKLYEPFNAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKK 231
+ ++L++ N L+ AE +K +N +LA ++S+ NE+ +
Sbjct: 167 ERLVSAAETFARLLQEGALKENIDTLYMGFTEAEAVKLFANTYLALRVSYFNELDTYSEM 226
Query: 232 LGIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEEL-GEDPIILKAVL 290
G+D+ + +GVGLD RI H+ G+GG C PKD K L+ E++ GE ++ A++
Sbjct: 227 TGLDTQAIIDGVGLDPRIGSHYNNPSFGYGGYCLPKDTKQLLANYEDIPGE---LIGAIV 283
Query: 291 QVNER-------QPLKLIELLKKHVPNL------KDMKVGVLGLAFKPNTDDVRETRAYI 337
+ N Q LK+++ N+ KD+ +G+ L K N+D+ R++
Sbjct: 284 RSNSTRKDFIADQVLKMVDYYDYSAHNIFDERVEKDIIIGIYRLTMKSNSDNFRQSSIQG 343
Query: 338 VIKKLLEEGAKVIAYDP--------------KAMENFKRFYPDVGRQISYANSAEEVLRE 383
++K++ +G +V+ Y+P +E FKR + Y NS E+V +
Sbjct: 344 IMKRIKAKGVRVVIYEPTLESGSTFFGSSVINDLEEFKRLSNAIVAN-RYDNSLEDVKEK 402
Query: 384 V 384
V
Sbjct: 403 V 403
>sp|Q04872|UDG1_ECOLI UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|485526|pir||S33668 hypothetical protein
(gnd 3' region) - Escherichia coli
>gi|41110|emb|CAA78939.1| (Z17241) putative
UDP-D-glucose dehydrogenase [Escherichia coli]
Length = 388
Score = 160 bits (401), Expect = 3e-38
Identities = 114/385 (29%), Positives = 199/385 (51%), Gaps = 25/385 (6%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
M ++I G+GYVGL G+ + + V+ +D+ KV ++N + PI ++ +EE + +
Sbjct: 1 MKITISGTGYVGLSNGI-LIAQHHEVVALDIVPTKVEMLNQKKSPIVDKEIEEYLATKQL 59
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVK 120
+ AT + +A D T++ + TP+ D + + I + N ++V+K
Sbjct: 60 NFRATTDKYDAY--RDGTYVIIATPTDYDPKTNYFNTSSVESVIRDVVDINPNA-VMVIK 116
Query: 121 STVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDER 180
ST+ G T +L++ G + +PEFLREG AL D L+P RIVIG + ER
Sbjct: 117 STIPVGFTN-----LLKERLGID-----NIFFSPEFLREGRALYDNLHPSRIVIGERSER 166
Query: 181 TKKVLEKLYEPF---NAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSW 237
+ L E + P LFTD AE IK +N +LA ++++ NE+ + + LG++S
Sbjct: 167 AGRFAALLQEGAVKKDIPTLFTDSTEAEAIKLFANTYLALRVAYFNELDSYAESLGLNSR 226
Query: 238 KVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQP 297
++ EGV LD RI H+ G+GG C PKD K L+ + + I+ A++ N +
Sbjct: 227 QIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYASVPNN--IIGAIVDANRTRK 284
Query: 298 LKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDPKAM 357
+ + + P + VGV L K +D+ R + ++K++ +G VI Y+P +
Sbjct: 285 DFIADSILARKPKV----VGVYRLIMKSGSDNFRASSIQGIMKRIKAKGVPVIIYEPVMV 340
Query: 358 ENFKRFYPDVGRQI-SYANSAEEVL 381
E+ + F+ V R + ++ N A+ ++
Sbjct: 341 ED-EFFHSRVVRDLTAFKNEADIII 364
>gb|AAF67264.1|AF169324_2 (AF169324) BcbB [Pasteurella multocida]
Length = 422
Score = 160 bits (400), Expect = 3e-38
Identities = 129/418 (30%), Positives = 213/418 (50%), Gaps = 39/418 (9%)
Query: 3 VSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEF--KG 60
+S+IG GY+GL T F + +VI +D++E V IN + I E LE+++Q+ KG
Sbjct: 7 ISVIGLGYIGLPTAAVFAQHHVKVIGIDINEHAVNTINQGKIHIVESDLEQVVQQCVNKG 66
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDG-TIDLTYVKNAAKEIGKALKEKDNFHIVVV 119
A+ A D I V TP K + DL+Y+K+A K I LK+ D ++V+
Sbjct: 67 DLKASLTPEPA----DAFLIAVPTPFKGNNYEPDLSYIKSACKMISSVLKKGD---LIVL 119
Query: 120 KSTVLPGTTEGV------IRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIV 173
+ST GTTE + R L D +A PE + G +++ + DRI+
Sbjct: 120 ESTSPVGTTEKMAIWLSEFRHDLTFPQQLGELSDIRIAHCPERVLPGHVMRELIENDRII 179
Query: 174 IGVQDERTKKVLEKLYEPF-NAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKL 232
G+ + ++ ++ LY+ F + T+ +TAEM K NAF I+FANE+ IC KL
Sbjct: 180 GGMTPKCSQMAVD-LYKTFVKGDCIVTNSRTAEMCKLTENAFRDVNIAFANELSIICDKL 238
Query: 233 GIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQV 292
GI+ W++ R+ + + G G GG C D ++ K EL + ++ V
Sbjct: 239 GINVWELINLANRHPRV--NILQPGCGVGGHCIAVDPWFIVNKTPELAK---LIHTARLV 293
Query: 293 NERQP--------LKLIELLKKHVPN--LKDMKVGVLGLAFKPNTDDVRETRAYIVIKKL 342
N+ +P +IE L+K+ PN L+D+K+ LGLAFKP+ DD+RE+ A + K+L
Sbjct: 294 NDSKPEWVINQVNNAVIEALQKN-PNKTLQDIKIACLGLAFKPDIDDLRESPALKITKQL 352
Query: 343 LEE-GAKVIAYDPKAMENFKRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFESL 399
+ ++ A +P N + + Q +S ++ L DV+++L + ++F+ +
Sbjct: 353 AAKYPNQITAVEP----NIEALPEQLITQNIKHSSLQQALETCDVLVVLVDHKEFKEI 406
>sp|P37791|UDG_SHIFL UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|530776|emb|CAA50782.1| (X71970) frame shift
mutation between 15882 and 15885 [Shigella flexneri]
Length = 372
Score = 159 bits (397), Expect = 8e-38
Identities = 103/357 (28%), Positives = 186/357 (51%), Gaps = 39/357 (10%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
M ++I G+GYVGL G+ + + V+ +D+ +V ++N+ PI ++ +++ +Q K
Sbjct: 1 MKITISGTGYVGLSNGL-LIAQNHEVVALDILPSRVAMLNDRISPIVDKEIQQFLQSDKI 59
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVK 120
+ AT + EA ++D ++ + TP+ D + + ++ + + K + E + + ++V+K
Sbjct: 60 HFNATLDKNEAYRDAD--YVIIATPTDYDPKTNY-FNTSSVESVIKDVVEINPYAVMVIK 116
Query: 121 STVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDER 180
STV G T + K ++ + +PEFLREG AL D L+P RIVIG + ER
Sbjct: 117 STVPVGFTAAM----------HKKYRTENIIFSPEFLREGKALYDNLHPSRIVIGERSER 166
Query: 181 TKKVLEKLYEPF---NAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSW 237
++ L E N P LFTD AE IK +N +LA ++++ NE+ + + LG+++
Sbjct: 167 AERFAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLNTR 226
Query: 238 KVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQP 297
++ EGV LD RI H+ G+GG C PKD K L+ + + + ++ A++ N
Sbjct: 227 QIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNN--LISAIVDANR--- 281
Query: 298 LKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDP 354
K V + K +D+ R + ++K++ +G +VI Y+P
Sbjct: 282 -----------------KWWVFIVIMKSGSDNFRASSIQGIMKRIKAKGVEVIIYEP 321
>pir||T44829 probable NDP-N-acetyl-D-galactosaminuronic acid dehydrogenase
[imported] - Acinetobacter lwoffii
>gi|6009990|emb|CAB57197.1| (AJ243431) putative
NDP-N-acetyl-D-galactosaminuronic acid dehydrogenase
[Acinetobacter lwoffii]
Length = 417
Score = 159 bits (397), Expect = 8e-38
Identities = 127/429 (29%), Positives = 209/429 (48%), Gaps = 37/429 (8%)
Query: 2 NVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEF--K 59
++ +IG GY+GL T F G +V VDV++ V +IN + I E L+ L+++ +
Sbjct: 7 HICVIGLGYIGLPTAATFAAHGVKVTGVDVNQHAVDMINQGKVHIVEPDLDALVRDVVAQ 66
Query: 60 GKYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVV 119
GK A EA D + V TP K D DL Y++ A+K + LK + +V++
Sbjct: 67 GKLSAQLAPTEA----DAYIVAVPTPFKDDYQPDLKYIEAASKALAPFLKSGN---LVIL 119
Query: 120 KSTVLPGTTEGV------IRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIV 173
+ST TE + RP L K D +A PE + G L++ ++ DRI
Sbjct: 120 ESTSPVEATEQMSAWLSEARPDLSFPQQKGEEADILVAHCPERVLPGKVLQELISNDRI- 178
Query: 174 IGVQDERTKKVLEKLYEPF-NAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKL 232
IG R K LY+ F + T+ +TAEM K N+F I+FANE+ IC KL
Sbjct: 179 IGGMTPRCSKAACDLYKIFVKGACIETNARTAEMCKLTENSFRDVNIAFANELSVICDKL 238
Query: 233 GIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQV 292
I+ W++ R++ + G G GG C D ++ K E +++ +V
Sbjct: 239 DINVWELISLANRHPRVN--ILQPGPGVGGHCIAVDPWFIVAKTPEQAR---LIRTAREV 293
Query: 293 NERQPLKLIELLKKHVPN---------LKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLL 343
N+ +P +I+ +K + + ++D+ + GLAFKP+ DD+RE+ A + KKL
Sbjct: 294 NDAKPEWVIDQVKIKIADFLQANPTKTIQDVTIACYGLAFKPDIDDLRESPALEITKKLA 353
Query: 344 EEGAKVIAYDPKAMENFKRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFESLDYSG 403
E+G ++A +P N + I E ++ D+ LIL + R F+++++S
Sbjct: 354 EQGFNILAIEP----NIHELPAKLPSNIKLIALKEH--QQADIHLILVDHRQFKNMNFSF 407
Query: 404 KIVIDGRRV 412
V+D + +
Sbjct: 408 SYVVDTKGI 416
>pir||B82264 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase VC0918
[imported] - Vibrio cholerae (group O1 strain N16961)
>gi|9655375|gb|AAF94080.1| (AE004175)
UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase
[Vibrio cholerae]
Length = 413
Score = 155 bits (389), Expect = 7e-37
Identities = 126/424 (29%), Positives = 208/424 (48%), Gaps = 31/424 (7%)
Query: 3 VSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQE--FKG 60
VS+IG GY+GL T G V+ VDV+ V IN + I E L+ +++ G
Sbjct: 5 VSVIGLGYIGLPTAAVLASRGLDVVGVDVNAHAVDTINKGEIHIVEPDLDIVVRSAVMTG 64
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDG-TIDLTYVKNAAKEIGKALKEKDNFHIVVV 119
K AT A D + V TP K D DL+Y++ AAK I L + + +VV+
Sbjct: 65 KLKATLTAEPA----DAFLVAVPTPFKGDNHEPDLSYIEAAAKTIAPVLAKGN---LVVL 117
Query: 120 KSTVLPGTTEGVI------RPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIV 173
+ST GTTE + RP L K D +A PE + G L++ ++ DR++
Sbjct: 118 ESTSPVGTTEKLAQWLAEARPDLTFPQQKGIAADVKIAYCPERVLPGYVLQELVSNDRVI 177
Query: 174 IGVQDERTKKVLEKLYEPF-NAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKL 232
GV ++K + LY+ F + T+ +TAEM K N+F I+FANE+ +C KL
Sbjct: 178 GGVSKACSEKAVA-LYKTFVKGECIVTNARTAEMAKLTENSFRDVNIAFANELSLVCNKL 236
Query: 233 GIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQV 292
I+ W++ R+S G G GG C D ++ + + +++ +V
Sbjct: 237 KINVWELIRLANRHPRVS--ILNPGPGVGGHCIAVDPWFIVNSCPDEAQ---LIRTAREV 291
Query: 293 NERQPLKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLE-EGAKVIA 351
N+ +P +++ +K+ K + LGLAFK + DD+RE+ A + K L E + +++A
Sbjct: 292 NDGKPHWVVDQVKQAADQFKKPIIACLGLAFKADIDDLRESPALDITKHLAESKVGQLLA 351
Query: 352 YDPKAMENFKRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFESLD---YSGKIVID 408
+P N + +Q S E L +++++L + ++F++ D ++ K+VID
Sbjct: 352 VEP----NITELPSKLAKQGIELVSLERALELANIVVVLVDHKEFKAADKTEFAKKVVID 407
Query: 409 GRRV 412
R V
Sbjct: 408 TRGV 411
>pir||F82417 UDP-glucose 6-dehydrogenase VCA0780 [imported] - Vibrio cholerae
(group O1 strain N16961) >gi|9658204|gb|AAF96678.1|
(AE004406) UDP-glucose 6-dehydrogenase [Vibrio cholerae]
Length = 388
Score = 155 bits (389), Expect = 7e-37
Identities = 106/362 (29%), Positives = 182/362 (49%), Gaps = 23/362 (6%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
M ++I G+GYVGL G+ + N V+ +D+ +V +N+ PI + +E +Q
Sbjct: 1 MKIAIAGTGYVGLSNGI-LLAQHNEVVALDIVVSRVEQLNDKISPIADPEIESFLQHQPL 59
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVK 120
+ AT + R+A D F+ + TP+ D + + I L I+V+K
Sbjct: 60 NFRATCDKRDAY--QDAQFVVIATPTDYDPQTNHFDTRTVEAVIDDVLAINPQA-IMVIK 116
Query: 121 STVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDER 180
STV G T+ + K+ L +PEFLREG AL D L P RI++G + ER
Sbjct: 117 STVPVGYTKRI----------KQRLCCNNLIFSPEFLREGRALYDNLYPSRIIVGEKSER 166
Query: 181 TKK---VLEKLYEPFNAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSW 237
+ +L + + + P L T AE +K SN +LA ++SF NE+ + G+D+
Sbjct: 167 GQAFATLLAQGAKKMDIPILLTHSTEAEAVKLFSNTYLAMRVSFFNELDTYAETHGLDTK 226
Query: 238 KVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQP 297
++ EGVGLD RI H+ G+GG C PKD + L++ E++ + +++A++ N +
Sbjct: 227 QIIEGVGLDPRIGNHYNNPSFGYGGYCLPKDTRQLLRNFEDVPNN--LIRAIVDANTTRK 284
Query: 298 LKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDPKAM 357
+ + + N VG+ L K +D+ R + ++K++ +G +V+ Y+P
Sbjct: 285 ----DHIAFSILNRNPKVVGIYRLIMKSGSDNFRASSILGIMKRIKAQGVEVVIYEPVLN 340
Query: 358 EN 359
E+
Sbjct: 341 ES 342
>gb|AAC46098.1| (U81973) Cap5O [Staphylococcus aureus]
Length = 420
Score = 155 bits (387), Expect = 1e-36
Identities = 123/427 (28%), Positives = 212/427 (48%), Gaps = 44/427 (10%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEF-- 58
M ++++G GY+GL T + F K G V+ VD+++ + + N Q I E GL+E+ +E
Sbjct: 1 MKLTVVGLGYIGLPTSIMFAKHGVDVLGVDINQQTIDKLQNGQISIEEPGLQEVYEEVLS 60
Query: 59 KGKYYATNNYREAILNSDITFITVGTPSKPD--GTIDLTYVKNAAKEIGKALKEKDNFHI 116
GK + SD+ I V TP+ D + D++ V A I LK+ +
Sbjct: 61 SGKLKVSTTPEA----SDVFIIAVPTPNNDDQYRSCDISLVMRALDSILPFLKKGNT--- 113
Query: 117 VVVKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGV 176
++V+ST+ P T + ++P++E G +D L PE + G L++ ++ +RI+ GV
Sbjct: 114 IIVESTIAPKTMDDFVKPVIENL-GFTIGEDIYLVHCPERVLPGKILEELVHNNRIIGGV 172
Query: 177 QDERTKKVLE---KLYEPF-NAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKL 232
TK +E ++Y F + TD +TAEM K N + I+ ANE+ IC L
Sbjct: 173 ----TKACIEAGKRVYRTFVQGEMIETDARTAEMSKLMENTYRDVNIALANELTKICNNL 228
Query: 233 GIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQV 292
I+ V E R++ H + G G GG C D +I K E + +++ ++
Sbjct: 229 NINVLDVIEMANKHPRVNIH--QPGPGVGGHCLAVDPYFIIAKDPENAK---LIQTGREI 283
Query: 293 NERQPLKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEE-GAKVIA 351
N P +++ K+ + L KV V GL +K + DD+RE+ A+ + + L +E +V A
Sbjct: 284 NNSMPAYVVDTTKQIIKALSGNKVTVFGLTYKGDVDDIRESPAFDIYELLNQEPDIEVCA 343
Query: 352 YDPKAMENFKRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFESLDYS------GKI 405
YDP +F V +S+A +++ ++LIL++ +F++L S K+
Sbjct: 344 YDPHVELDF------VEHDMSHA------VKDASLVLILSDHSEFKNLSDSHFDKMKHKV 391
Query: 406 VIDGRRV 412
+ D + V
Sbjct: 392 IFDTKNV 398
>gi|9632145 PBCV-1 UDP-glucose dehydrogenase [Paramecium bursaria Chlorella
virus 1] >gi|7431390|pir||T18111 probable UDPglucose
6-dehydrogenase (EC 1.1.1.22) - Chlorella virus PBCV-1
>gi|2447087|gb|AAC96945.1| (U42580) PBCV-1 UDP-glucose
dehydrogenase [Paramecium bursaria Chlorella virus 1]
Length = 389
Score = 153 bits (384), Expect = 3e-36
Identities = 110/389 (28%), Positives = 187/389 (47%), Gaps = 31/389 (7%)
Query: 3 VSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKGKY 62
++++G GYVG + + N VI +D+ E +V++I N + PI ++ +EE ++
Sbjct: 4 IAVVGCGYVGTACAV-LLAQKNEVIVLDISEDRVQLIKNKKSPIEDKEIEEFLETKDLNL 62
Query: 63 YATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVKST 122
AT + A N++ F+ + TP+ D K+ IG +K +V+KST
Sbjct: 63 TATTDKVLAYENAE--FVIIATPTDYDVVTRYFNTKSVENVIGDVIKNTQTHPTIVIKST 120
Query: 123 VLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDERTK 182
+ G + V ++ F + +PEFLREG AL D L P RI++G
Sbjct: 121 IPIGFVDKV----------REQFDYQNIIFSPEFLREGRALYDNLYPSRIIVGDDSPIAL 170
Query: 183 KVLEKLYEPFN---APKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSWKV 239
K L E AP L + AE +K SN +LA ++++ NE+ G+++ ++
Sbjct: 171 KFANLLVEGSKTPLAPVLTMGTREAEAVKLFSNTYLAMRVAYFNELDTFAMSHGMNAKEI 230
Query: 240 FEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQPLK 299
+GV L+ RI + G+G CFPKD K L+ E + +D I+ A+++ NE +
Sbjct: 231 IDGVTLEPRIGQGYSNPSFGYGAYCFPKDTKQLLANFEGVPQD--IIGAIVESNETRK-- 286
Query: 300 LIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDPKAMEN 359
E++ V N VGV LA K +D+ R + ++++L +G + ++P +E
Sbjct: 287 --EVIVSEVENRFPTTVGVYKLAAKAGSDNFRSSAIVDIMERLANKGYHIKIFEP-TVEQ 343
Query: 360 FKRFYPDVGRQISYANSAEEVLREVDVIL 388
F+ F D N+ E DVI+
Sbjct: 344 FENFEVD--------NNLTTFATESDVII 364
>gb|AAC67251.2| (AF067175) UDP-glucose dehydrogenase [Pasteurella multocida]
Length = 390
Score = 153 bits (384), Expect = 3e-36
Identities = 106/384 (27%), Positives = 188/384 (48%), Gaps = 27/384 (7%)
Query: 3 VSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKGKY 62
++I G+GYVGL + + N VI +D+D+ KV +INN + PI ++ +E+ +Q
Sbjct: 4 ITIAGAGYVGLSNAVLLAQHHN-VILLDIDQNKVDLINNKKSPITDKEIEDFLQNKSLTM 62
Query: 63 YATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKE--IGKALKEKDNFHIVVVK 120
AT + A+ N+D F+ + TP+ D + Y + E I + L I++ K
Sbjct: 63 MATTDKEVALKNAD--FVIIATPT--DYNTETGYFNTSTVEAVIEQTLSINPQATIII-K 117
Query: 121 STVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDER 180
ST+ G TE + ++ F L +PEF+REG AL D L P RI++G +
Sbjct: 118 STIPVGFTENM----------REKFNTPNLIFSPEFVREGKALYDNLYPSRIIVGSTSYQ 167
Query: 181 TKKVLEKLYE---PFNAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSW 237
K + L + + LFT AE +K +N +LA +++F NE+ +++
Sbjct: 168 AKVFADMLTQCARKKDVTVLFTHNTEAEAVKLFANTYLAMRVAFFNELDTYASLHHLNTK 227
Query: 238 KVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQP 297
+ G+ D RI H+ G+GG C PKD K L+ ++ ++ +++A+++ NE +
Sbjct: 228 DIINGISTDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYADVPQN--LIEAIVKSNETRK 285
Query: 298 LKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDPKAM 357
+ V N K VG+ L K +D+ R + ++ L E G +++ Y+P
Sbjct: 286 ----RFITHDVLNKKPKTVGIYRLIMKSGSDNFRASAILDIMPHLKENGVEIVIYEPTLN 341
Query: 358 ENFKRFYPDVGRQISYANSAEEVL 381
+ YP + + + N ++ +L
Sbjct: 342 QQAFEDYPVINQLSEFINRSDVIL 365
>emb|CAB46919.2| (AJ242946) putative UDP-glucose dehydrogenase [Streptococcus
uberis]
Length = 401
Score = 153 bits (383), Expect = 3e-36
Identities = 108/374 (28%), Positives = 187/374 (49%), Gaps = 30/374 (8%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
M +++ GSGYVGL + + N V VD+ E KV +IN Q PI + +E ++E K
Sbjct: 1 MKIAVAGSGYVGLSLSV-LLAQKNPVTVVDIIEKKVNLINQKQSPIQDVDIENYLKEKKL 59
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVK 120
+ AT + +A ++DI + + TP+ D + + I KAL ++V+K
Sbjct: 60 QLRATLDADQAFRDADI--LIIATPTNYDVEKNFFDTSHVETVIEKALALNSQA-LLVIK 116
Query: 121 STVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDER 180
ST+ G I+ + +KY + + +PEFLRE ALKD L P RI++ +D+
Sbjct: 117 STI----PLGFIKKMRQKYQTDR------IIFSPEFLRESKALKDNLYPSRIIVSFEDDD 166
Query: 181 TKKVLE--KLYEPF--------NAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICK 230
+ +V+E K + + P LF AE +K +N +LA ++S+ NE+ +
Sbjct: 167 SMEVIEAAKTFAQLLKDGSLDKDVPVLFMGSAEAEAVKLFANTYLAMRVSYFNELDTYAE 226
Query: 231 KLGIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVL 290
K G+ + EGV D RI H+ G+GG C PKD K L+ + + + ++KA++
Sbjct: 227 KNGLRVDNIIEGVCHDRRIGIHYNNPSFGYGGYCLPKDTKQLLAGYDGIPQS--LIKAIV 284
Query: 291 QVNERQPLKLIELLKKHVPNL----KDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEG 346
N+ + + + + + ++ KD +G+ L K N+D+ RE+ +I +
Sbjct: 285 DSNKIRKEYIASQILQQLSDINVDPKDATIGIYRLIMKSNSDNFRESAIKDIIDHIKSYQ 344
Query: 347 AKVIAYDPKAMENF 360
++ Y+P E+F
Sbjct: 345 INIVLYEPMMNEDF 358
>gb|AAB49444.1| (U73374) Cap8O [Staphylococcus aureus]
Length = 420
Score = 150 bits (376), Expect = 2e-35
Identities = 124/427 (29%), Positives = 211/427 (49%), Gaps = 44/427 (10%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEF-- 58
M ++++G GY+GL T + F K G V+ VD+++ + + + Q I E GL+E+ +E
Sbjct: 1 MKLTVVGLGYIGLPTSIMFAKHGVDVLGVDINQQTIDKLQSGQISIEEPGLQEVYEEVLS 60
Query: 59 KGKYYATNNYREAILNSDITFITVGTPSKPD--GTIDLTYVKNAAKEIGKALKEKDNFHI 116
GK + SD+ I V TP+ D + D++ V A I L EK N
Sbjct: 61 SGKLKVSTTPEA----SDVFIIAVPTPNNDDQYRSCDISLVMRALDSILPFL-EKGN--T 113
Query: 117 VVVKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGV 176
++V+ST+ P T + ++P++E G +D L PE + G L++ ++ +RI+ GV
Sbjct: 114 IIVESTIAPKTMDDFVKPVIENL-GFTIGEDIYLVHCPERVLPGKILEELVHNNRIIGGV 172
Query: 177 QDERTKKVLEK---LYEPF-NAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKL 232
TK +E +Y F + TD +TAEM K N + I+ ANE+ IC L
Sbjct: 173 ----TKACIEAGKYVYRTFVQGEMIETDARTAEMSKLMENTYRDVNIALANELTKICNNL 228
Query: 233 GIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQV 292
I+ V E R++ H + G G GG C D +I K E + +++ ++
Sbjct: 229 NINVLVVIEMANKHPRVNIH--QPGPGVGGHCLAVDPYFIIAKDPENAK---LIQTGREI 283
Query: 293 NERQPLKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEE-GAKVIA 351
N P +++ K+ + L KV V GL +K + DD+RE+ A+ + + L +E +V A
Sbjct: 284 NNSMPAYVVDTTKQIIKALSGNKVTVFGLTYKGDVDDIRESPAFDIYELLNQEPDIEVCA 343
Query: 352 YDPKAMENFKRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFESLDYS------GKI 405
YDP +F V +S+A +++ ++LIL++ +F++L S K+
Sbjct: 344 YDPHVELDF------VEHDMSHA------VKDASLVLILSDHSEFKNLSDSHFDKMKHKV 391
Query: 406 VIDGRRV 412
+ D + V
Sbjct: 392 IFDTKNV 398
>gb|AAF08248.1|AF170495_9 (AF170495) UDP-N-acetylglucosamine-2-epimerase [Pasteurella
haemolytica]
Length = 423
Score = 148 bits (369), Expect = 1e-34
Identities = 127/415 (30%), Positives = 207/415 (49%), Gaps = 38/415 (9%)
Query: 3 VSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEF--KG 60
+S++G GY+GL T F + G VI VDV++ V IN + I E L+ + + G
Sbjct: 7 ISVVGLGYIGLPTATVFAQHGLNVIGVDVNQHAVDHINQGKIHIVEPDLDVAVHQCVSSG 66
Query: 61 KYYATNNYREAILNSDITFITVGTPSK-PDGTIDLTYVKNAAKEIGKALKEKDNFHIVVV 119
K AT A + I V TP K D DL+Y++ A K I L EK N +V++
Sbjct: 67 KLKATLTPEPA----EAFLIAVPTPFKGQDYEPDLSYIQAACKAIAPVL-EKGN--LVIL 119
Query: 120 KSTVLPGTTEGVIRPILEKYSGKKAF-------QDFGLAMNPEFLREGVALKDFLNPDRI 172
+ST G TE + + E Y + +F D +A PE + G + + + DRI
Sbjct: 120 ESTSPVGATEQMAEWLAE-YRPELSFPQQAGEDSDIRIAHCPERVLPGQVMHELIENDRI 178
Query: 173 VIGVQDERTKKVLEKLYEPF-NAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKK 231
V G+ ++ + + + LY+ F + T+ +TAEM K N+F I+FANE+ IC +
Sbjct: 179 VGGMTNKCSVQAVN-LYKTFVKGDCIVTNARTAEMCKLTENSFRDVNIAFANELSIICDR 237
Query: 232 LGIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQ 291
L I+ W++ R+ + + G G GG C D ++ K +L + I++ +
Sbjct: 238 LDINVWELIALANRHPRV--NILQPGCGVGGHCIAVDPWFIVNKTPDLAK---IIRTGRE 292
Query: 292 VNERQP--------LKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLL 343
VN+ +P +I L+K ++ +K+ LGLAFKP+ DD+RE+ A + +KL
Sbjct: 293 VNDHKPEWVISKMNEAVIYALQKTGKSIDQIKIACLGLAFKPDIDDLRESPALKITEKLA 352
Query: 344 EE-GAKVIAYDPKAMENFKRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFE 397
E+ +V A +P E K+ + IS S +E L DV+++L + +F+
Sbjct: 353 EKYPNQVFAVEPNVEELPKKL---ANKNISLI-SVDEALEVADVVVVLVDHSEFK 403
>sp|Q07172|UDG_STRPY UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|1075776|pir||A46089 UDPglucose
6-dehydrogenase (EC 1.1.1.22) - Streptococcus pyogenes
>gi|8569328|pdb|1DLI|A Chain A, The First Structure Of
Udp-Glucose Dehydrogenase (Udpgdh) Reveals The Catalytic
Residues Necessary For The Two-Fold Oxidation
>gi|295189|gb|AAA26899.1| (L08444) UDP-glucose
hydrogenase [Streptococcus pyogenes]
Length = 402
Score = 141 bits (353), Expect = 1e-32
Identities = 105/371 (28%), Positives = 179/371 (47%), Gaps = 38/371 (10%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
M +++ GSGYVGL G+ + L N V VD+ KV INN PI +E +E ++ +
Sbjct: 1 MKIAVAGSGYVGLSLGV-LLSLQNEVTIVDILPSKVDKINNGLSPIQDEYIEYYLKSKQL 59
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDGTI---DLTYVKNAAKEIGKALKEKDNFHIV 117
AT + + A +++ + + TP+ + I D +V+ KE+ N H
Sbjct: 60 SIKATLDSKAAYKEAEL--VIIATPTNYNSRINYFDTQHVETVIKEVLSV-----NSHAT 112
Query: 118 VVKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQ 177
++ + +P G I + +K FQ + +PEFLRE AL D L P RI++ +
Sbjct: 113 LIIKSTIP---IGFITEMRQK------FQTDRIIFSPEFLRESKALYDNLYPSRIIVSCE 163
Query: 178 DERTKKV----------LEKLYEPFNAPKLFTDIKTAEMIKYASNAFLATKISFANEIGN 227
+ + KV L+ + N P L AE +K +N +LA ++++ NE+
Sbjct: 164 ENDSPKVKADAEKFALLLKSAAKKNNVPVLIMGASEAEAVKLFANTYLALRVAYFNELDT 223
Query: 228 ICKKLGIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILK 287
+ ++S + +G+ D RI H+ G+GG C PKD K L+ + + +++
Sbjct: 224 YAESRKLNSHMIIQGISYDDRIGMHYNNPSFGYGGYCLPKDTKQLLANYNNIPQ--TLIE 281
Query: 288 AVLQVNERQ----PLKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLL 343
A++ N + ++I +LK+ +K VGV L K N+D+ RE+ VI L
Sbjct: 282 AIVSSNNVRKSYIAKQIINVLKEQESPVK--VVGVYRLIMKSNSDNFRESAIKDVIDILK 339
Query: 344 EEGAKVIAYDP 354
+ K+I Y+P
Sbjct: 340 SKDIKIIIYEP 350
>gb|AAD56735.1|AF125164_8 (AF125164) UDP-ManNAc dehydrogenase [Bacteroides fragilis]
Length = 408
Score = 138 bits (344), Expect = 1e-31
Identities = 115/417 (27%), Positives = 203/417 (48%), Gaps = 32/417 (7%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
M+ +G GY+GL T + K G +V VD++ V + N + I E G++++++E
Sbjct: 1 MDACFMGLGYIGLPTAIIAAKHGVKVTGVDINPKVVEMTNEGKLHIIEPGMQDILEEVVA 60
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVK 120
T + + SD F+ V TP K + D++YV+ A + I LKE D + V++
Sbjct: 61 NGMLTASTIPTV--SDAYFMVVPTPFKGNHEPDISYVEAATRAIIPFLKEGD---LYVIE 115
Query: 121 STVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDER 180
ST GTT G + ++ + + + +A PE + G + + ++ DR++ G+ +
Sbjct: 116 STSPVGTT-GKMADLIFSLRPELRCKIY-IAYCPERVLPGNVIYELVHNDRVIGGIDERS 173
Query: 181 TKKVLEKLYEPFNAPKLF-TDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSWKV 239
T K +E Y F KL TD KTAEM K N+ +I+FANE+ IC K GI+ W++
Sbjct: 174 TDKAIE-FYSQFVKGKLHKTDCKTAEMCKLTENSSRDVQIAFANELSLICDKAGINVWEL 232
Query: 240 FEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQPLK 299
+ R+ + + G GG C D A+ E II KA ++N +
Sbjct: 233 IDLANKHPRV--NILQPSCGVGGHCIAVD--PYFITADFPIESQIIAKA-REINNYKAFW 287
Query: 300 LI-----ELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLE--EGAKVIAY 352
E+LK + + + ++GLAFKP+ DD+RE A + K+++ A ++
Sbjct: 288 CAEKVENEMLKFEIKYGRKPIIAMMGLAFKPDIDDLREAPAKYITTKVMQSCNNADILVV 347
Query: 353 DPKAMENFKRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFESLDY-SGKIVID 408
+P +E+ ++ + ++ + D+I+ L F++L Y K+++D
Sbjct: 348 EPNVVEH----------KVFKLTNYKDAYAKADIIVFLVAHSVFKTLLYDDNKVILD 394
>pdb|1DLJ|A Chain A, The First Structure Of Udp-Glucose Dehydrogenase (Udpgdh)
Reveals The Catalytic Residues Necessary For The
Two-Fold Oxidation
Length = 402
Score = 138 bits (343), Expect = 2e-31
Identities = 104/371 (28%), Positives = 178/371 (47%), Gaps = 38/371 (10%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
M +++ GSGYVGL G+ + L N V VD+ KV INN PI +E +E ++ +
Sbjct: 1 MKIAVAGSGYVGLSLGV-LLSLQNEVTIVDILPSKVDKINNGLSPIQDEYIEYYLKSKQL 59
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDGTI---DLTYVKNAAKEIGKALKEKDNFHIV 117
AT + + A +++ + + TP+ + I D +V+ KE+ N H
Sbjct: 60 SIKATLDSKAAYKEAEL--VIIATPTNYNSRINYFDTQHVETVIKEVLSV-----NSHAT 112
Query: 118 VVKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQ 177
++ + +P G I + +K FQ + +PEFLRE AL D L P RI++ +
Sbjct: 113 LIIKSTIP---IGFITEMRQK------FQTDRIIFSPEFLRESKALYDNLYPSRIIVSCE 163
Query: 178 DERTKKV----------LEKLYEPFNAPKLFTDIKTAEMIKYASNAFLATKISFANEIGN 227
+ + KV L+ + N P L AE +K +N +LA ++++ NE+
Sbjct: 164 ENDSPKVKADAEKFALLLKSAAKKNNVPVLIMGASEAEAVKLFANTYLALRVAYFNELDT 223
Query: 228 ICKKLGIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILK 287
+ ++S + +G+ D RI H+ G+GG PKD K L+ + + +++
Sbjct: 224 YAESRKLNSHMIIQGISYDDRIGMHYNNPSFGYGGYSLPKDTKQLLANYNNIPQ--TLIE 281
Query: 288 AVLQVNERQ----PLKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLL 343
A++ N + ++I +LK+ +K VGV L K N+D+ RE+ VI L
Sbjct: 282 AIVSSNNVRKSYIAKQIINVLKEQESPVK--VVGVYRLIMKSNSDNFRESAIKDVIDILK 339
Query: 344 EEGAKVIAYDP 354
+ K+I Y+P
Sbjct: 340 SKDIKIIIYEP 350
>pir||B49350 hypothetical protein 379 (nfrC 3' region) - Escherichia coli
Length = 420
Score = 137 bits (341), Expect = 3e-31
Identities = 111/417 (26%), Positives = 202/417 (47%), Gaps = 38/417 (9%)
Query: 3 VSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQE-FKGK 61
+S+IG GY+GL T F +VI VD+++ V IN + I E L +++ +G
Sbjct: 6 ISVIGLGYIGLPTAAAFASRQKQVIGVDINQHAVDTINRGEIHIVEPDLASVVKTAVEGG 65
Query: 62 YYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVKS 121
+ + + +D I V TP K D D+TYV++AA+ I LK+ +V+++S
Sbjct: 66 FLRAST---TPVEADAWLIAVPTPFKGDHEPDMTYVESAARSIAPVLKKGA---LVILES 119
Query: 122 TVLPGTTEGV------IRPILE--KYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIV 173
T G+TE + +RP L + G++A D +A PE + G + + + DR++
Sbjct: 120 TSPVGSTEKMAEWLAEMRPDLTFPQQVGEQA--DVNIAYCPERVLPGQVMVELIKNDRVI 177
Query: 174 IGVQDERTKKVLEKLYEPF-NAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKL 232
G+ + + E LY+ F + T+ +TAEM K N+F I+FANE+ IC
Sbjct: 178 GGMTPVCSARASE-LYKIFLEGECVVTNSRTAEMCKLTENSFRDVNIAFANELSLICADQ 236
Query: 233 GIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQV 292
GI+ W++ R+ + + G G GG C D ++ + + +++ +V
Sbjct: 237 GINVWELIRLANRHPRV--NILQPGPGVGGHCIAVDPWFIVAQNPQQAR---LIRTAREV 291
Query: 293 NERQPLKLIELLKKHVPN--------LKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLE 344
N+ +P +I+ +K V + ++K+ GLAFKPN DD+RE+ A + + + +
Sbjct: 292 NDHKPFWVIDQVKAAVADCLAATDKRASELKIACFGLAFKPNIDDLRESPAMEIAELIAQ 351
Query: 345 -EGAKVIAYDPKAMENFKRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFESLD 400
+ + +P + K+ + +E L DV+++L + F+ ++
Sbjct: 352 WHSGETLVVEPNIHQLPKKL-----TGLCTLAQLDEALATADVLVMLVDHSQFKVIN 403
>sp|P39861|CAPL_STAAU CAPL PROTEIN >gi|506708|gb|AAA64651.1| (U10927) CapL
[Staphylococcus aureus]
Length = 424
Score = 136 bits (339), Expect = 5e-31
Identities = 119/407 (29%), Positives = 192/407 (46%), Gaps = 36/407 (8%)
Query: 2 NVSIIGSGYVGLVTGMGFVKLGNR--VIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFK 59
N++++G GYVGL + F GN+ VI D++E +++ + N Y+ E + K
Sbjct: 4 NIAVVGLGYVGLPVAVTF---GNKHKVIGFDINESRIKELKNN----YDRTNEVTENKLK 56
Query: 60 GKYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVV 119
+ E + +D I V TP DL + A++ +GK + IVV
Sbjct: 57 NTNIEYTSNAEDLKKADFIIIAVPTPIDKHNKPDLLPLLKASETVGKVITPDT---IVVY 113
Query: 120 KSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDE 179
+STV PG TE P+LEKYSG +DF + +PE + G + F ++V G
Sbjct: 114 ESTVYPGATEEECVPVLEKYSGLVCGKDFFVGYSPERINPGDKVHTFETITKVVSG---- 169
Query: 180 RTKKVLEKLYEPFNA-----PKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGI 234
+T +VLE + + +++ + IK AE K N I+ NE+ I KL I
Sbjct: 170 QTLEVLEIVADVYSSVVTAGVHKASSIKVAEAAKVIENTQRDVNIALMNELAIIFDKLDI 229
Query: 235 DSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNE 294
D+ +V + G F+ G+ GG C D L KA+E+G P ++ A ++N+
Sbjct: 230 DTNEVLKASGTKWNFLN--FKPGL-VGGHCIGVDPYYLTHKAQEVGHHPEVILAGRRIND 286
Query: 295 RQ----PLKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVI 350
+I+ L K ++ V VLGL FK N D+R T+ +I++L E G V
Sbjct: 287 NMAKYIASNVIKELLKQGLEVQGATVNVLGLTFKENCPDLRNTKVIHIIEELKEYGLNVT 346
Query: 351 AYDPKAMEN-FKRFYPDVGRQISYANSAEEVLREVDVILILTEWRDF 396
D +A +N K+F+ + ++ E L+ VDV+L +D+
Sbjct: 347 VNDVEADKNEAKKFF-----GLDLIDTKE--LKMVDVVLFAVPHKDY 386
>sp|P27829|WECC_ECOLI UDP-N-ACETYL-D-MANNOSAMINURONIC ACID DEHYDROGENASE (UDP-MANNACA
DEHYDROGENASE) >gi|7449840|pir||F65182 UDP-ManNAc
dehydrogenase - Escherichia coli
>gi|2367284|gb|AAC76792.1| (AE000455)
UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase;
synthesis of enterobacterial common antigen (ECA)
[Escherichia coli K12]
Length = 420
Score = 136 bits (339), Expect = 5e-31
Identities = 111/417 (26%), Positives = 202/417 (47%), Gaps = 38/417 (9%)
Query: 3 VSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQE-FKGK 61
+S+IG GY+GL T F +VI VD+++ V IN + I E L +++ +G
Sbjct: 6 ISVIGLGYIGLPTAAAFASRQKQVIGVDINQHAVDTINRGEIHIVEPDLASVVKTAVEGG 65
Query: 62 YYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVKS 121
+ + + +D I V TP K D D+TYV++AA+ I LK+ +V+++S
Sbjct: 66 FLRAST---TPVEADRWLIAVPTPFKGDHEPDMTYVESAARSIAPVLKKGA---LVILES 119
Query: 122 TVLPGTTEGV------IRPILE--KYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIV 173
T G+TE + +RP L + G++A D +A PE + G + + + DR++
Sbjct: 120 TSPVGSTEKMAEWLAEMRPDLTFPQQVGEQA--DVNIAYCPERVLPGQVMVELIKNDRVI 177
Query: 174 IGVQDERTKKVLEKLYEPF-NAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKL 232
G+ + + E LY+ F + T+ +TAEM K N+F I+FANE+ IC
Sbjct: 178 GGMTPVCSARASE-LYKIFLEGECVVTNSRTAEMCKLTENSFRDVNIAFANELSLICADQ 236
Query: 233 GIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQV 292
GI+ W++ R+ + + G G GG C D ++ + + +++ +V
Sbjct: 237 GINVWELIRLANRHPRV--NILQPGPGVGGHCIAVDPWFIVAQNPQQAR---LIRTAREV 291
Query: 293 NERQPLKLIELLKKHVPN--------LKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLE 344
N+ +P +I+ +K V + ++K+ GLAFKPN DD+RE+ A + + + +
Sbjct: 292 NDHKPFWVIDQVKAAVADCLAATDKRASELKIACFGLAFKPNIDDLRESPAMEIAELIAQ 351
Query: 345 -EGAKVIAYDPKAMENFKRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFESLD 400
+ + +P + K+ + +E L DV+++L + F+ ++
Sbjct: 352 WHSGETLVVEPNIHQLPKKL-----TGLCTLAQLDEALATADVLVMLVDHSQFKVIN 403
>sp|Q57346|UDG_STRPN UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|1658317|emb|CAA87403.1| (Z47210) uridine
diphosphate glucose dehydrogenase [Streptococcus
pneumoniae]
Length = 394
Score = 132 bits (329), Expect = 7e-30
Identities = 112/407 (27%), Positives = 194/407 (47%), Gaps = 49/407 (12%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
M ++I GSGYVGL + + + V +DV + KV INN + PI +E +E+ + E +
Sbjct: 1 MKIAIAGSGYVGLSLAV-LLAQHHEVKVIDVIKDKVESINNRKSPIKDEAIEKYLVEKEL 59
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIG-KALKEKDNFHIVVV 119
A+ + A + D+ + + TP+ D +DL ++ E K E ++ +V+
Sbjct: 60 NLEASLD--PAHVYKDVEYAIIATPTNYD--VDLNQFDTSSVEAAIKTCMEYNDTCTIVI 115
Query: 120 KSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQ-- 177
KST+ EG + + EK++ + + +PEFLRE AL D L P RIV+G
Sbjct: 116 KSTI----PEGYTKEVREKFNTDR------IIFSPEFLRESKALYDNLYPSRIVVGTDLD 165
Query: 178 -DERTKK------VLEKLYEPFNAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICK 230
E TK+ +L+ P L AE+ K SN +LAT++ + NEI +
Sbjct: 166 DSELTKRAWQFADLLKGGAIKEEVPILVVAFNEAEVAKLFSNTYLATRVRYFNEIDTYSE 225
Query: 231 KLGIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVL 290
G++ + + V D RI ++ G+GG C PKD K L ++ E+ ++ AV+
Sbjct: 226 VKGLNPKTIIDIVCYDPRIGSYYNNPSFGYGGYCLPKDTKQLKASFRDVPEN--LITAVV 283
Query: 291 QVNERQPLKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVI 350
Q N+ + + + P++ VG+ L K ++D+ R + V+++L G +++
Sbjct: 284 QSNKTRKDYIAGAILAKQPSV----VGIYRLIMKSDSDNFRSSAVKGVMERLDNYGKEIV 339
Query: 351 AYDP-------------KAMENFKRFYPDVGRQISYANSAEEVLREV 384
Y+P K+++ FK I AN + LR++
Sbjct: 340 IYEPTIECDTFMGYRVIKSLDEFKNI-----SDIVVANRMNDDLRDI 381
>gb|AAC43311.1| (U15171) UDP-glucose dehydrogenase [Streptococcus pneumoniae]
>gi|1095716|prf||2109359A UDP-glucose dehydrogenase
[Streptococcus pneumoniae]
Length = 394
Score = 132 bits (328), Expect = 9e-30
Identities = 112/407 (27%), Positives = 194/407 (47%), Gaps = 49/407 (12%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
M ++I GSGYVGL + + + V +DV + KV INN + PI +E +E+ + E +
Sbjct: 1 MKIAIAGSGYVGLSLAV-LLAQHHEVKVIDVIKDKVESINNRKSPIKDEAIEKYLVEKEL 59
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIG-KALKEKDNFHIVVV 119
A+ + A + D+ + + TP+ D +DL ++ E K E ++ +V+
Sbjct: 60 NLEASLD--PAHVYKDVEYAIIATPTNYD--VDLNQFDTSSVEAAIKTCMEYNDTCTIVI 115
Query: 120 KSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQ-- 177
KST+ EG + + EK++ + + +PEFLRE AL D L P RIV+G
Sbjct: 116 KSTI----PEGYTKEVREKFNTDR------IIFSPEFLRESKALYDNLYPSRIVVGTDLD 165
Query: 178 -DERTKK------VLEKLYEPFNAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICK 230
E TK+ +L+ P L AE+ K SN +LAT++++ NEI +
Sbjct: 166 DSELTKRAWQFADLLKGGAIKEEVPILVVAFNEAEVAKLFSNTYLATRVAYFNEIDTYSE 225
Query: 231 KLGIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVL 290
G++ + + V D RI + G+GG C PKD K L ++ E+ ++ AV+
Sbjct: 226 VKGLNPKTIIDIVCYDPRIGSDYNNPSFGYGGYCLPKDTKQLKASFRDVPEN--LITAVV 283
Query: 291 QVNERQPLKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVI 350
Q N+ + + + P++ VG+ L K ++D+ R + V+++L G +++
Sbjct: 284 QSNKTRKDYIAGAILAKQPSV----VGIYRLIMKSDSDNFRSSAVKGVMERLDNYGKEIV 339
Query: 351 AYDP-------------KAMENFKRFYPDVGRQISYANSAEEVLREV 384
Y+P K+++ FK I AN + LR++
Sbjct: 340 IYEPTIECDTFMGYRVIKSLDEFKNI-----SDIVVANRMNDDLRDI 381
>gb|AAF33466.1| (AF233324) 90% identity with E. coli
UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase
(WECC) (SP:P27829); contains similarity to Pfam family
PF00984 (UDP-glucose/GDP-mannose dehydrogenase family),
score=633.4, E=1.2e-186, N=1 [Salmonella typhimurium >
Length = 420
Score = 129 bits (321), Expect = 6e-29
Identities = 111/417 (26%), Positives = 194/417 (45%), Gaps = 40/417 (9%)
Query: 3 VSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEEL--MQEFKG 60
+S+IG GY+GL T F +VI VD+++ V +IN + I E L + M G
Sbjct: 6 ISVIGLGYIGLPTAAAFASRQKQVIGVDINQHAVDIINRGEIHIVEPALGNVVKMAVEGG 65
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVK 120
AT EA D I V TP K D D+ YV+ AAK I LK+ +V+++
Sbjct: 66 FLRATTTPVEA----DAYLIAVPTPFKGDHDPDMAYVEAAAKSIAPVLKKGA---LVILE 118
Query: 121 STVLPGTTEGVIRPI--------LEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRI 172
ST G TE + + + +G++A D +A PE + G + + + DR+
Sbjct: 119 STSPVGATEQMAGWLAGMRTDLTFPQQAGEQA--DVNIAYCPERVLPGQVMVELIKNDRV 176
Query: 173 VIGVQDERTKKVLEKLYEPF-NAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKK 231
+ G+ + + LY+ F + T+ +TAEM K N+F I+FANE+ IC +
Sbjct: 177 IGGMTPVCSARA-SALYKIFLEGECVVTNSRTAEMCKLTENSFRDVNIAFANELSLICAE 235
Query: 232 LGIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQ 291
GI+ W++ R+ + + G G GG C D ++ + + +++ +
Sbjct: 236 QGINVWELIRLANRHPRV--NILQPGPGVGGHCIAVDPWFIVAQNPQQAR---LIRTARE 290
Query: 292 VNERQPLKLIELLKKHVPN--------LKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLL 343
VN+ +P +++ +K V + ++K+ GLAFKPN DD+RE+ A + + +
Sbjct: 291 VNDGKPHWVVDQVKAAVTDCLAATDKRASEVKIACFGLAFKPNIDDLRESPAMGIAQSIA 350
Query: 344 E-EGAKVIAYDPKAMENFKRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFESL 399
+ + +P R P + + L DV+++L + +F+++
Sbjct: 351 RWHSGETLVVEPNI-----RQLPKKLDGLCTLAKLDAALAAADVLVMLVDHDEFKAI 402
>pir||S30681 hypothetical protein o379 - Escherichia coli
>gi|148190|gb|AAA67587.1| (M87049) possibly rffD;
(UDP-ManNAc dehydrogenase) [Escherichia coli]
Length = 379
Score = 128 bits (319), Expect = 1e-28
Identities = 103/351 (29%), Positives = 176/351 (49%), Gaps = 33/351 (9%)
Query: 3 VSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQE-FKGK 61
+S+IG GY+GL T F +VI VD+++ V IN + I E L +++ +G
Sbjct: 6 ISVIGLGYIGLPT-RAFASRQKQVIGVDINQHAVDTINRGEIHIVEPDLASVVKTAVEGG 64
Query: 62 YYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVKS 121
+ + + +D I V TP K D D+TYV++AA+ I LK+ +V+++S
Sbjct: 65 FLRAST---TPVEADRWLIAVPTPFKGDHEPDMTYVESAARSIAPVLKKGA---LVILES 118
Query: 122 TVLPGTTEGV------IRPILE--KYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIV 173
T G+TE + +RP L + G++A D +A PE + G + + + DR++
Sbjct: 119 TSPVGSTEKMAEWLAEMRPDLTFPQQVGEQA--DVNIAYCPERVLPGQVMVELIKNDRVI 176
Query: 174 IGVQDERTKKVLEKLYEPF-NAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKL 232
G+ + + E LY+ F + T+ +TAEM K N+F I+FANE+ IC
Sbjct: 177 GGMTPVCSARASE-LYKIFLEGECVVTNSRTAEMCKLTENSFRDVNIAFANELSLICADQ 235
Query: 233 GIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQV 292
GI+ W++ R+ + + G G GG C D ++ + + +++ +V
Sbjct: 236 GINVWELIRLANRHPRV--NILQPGPGVGGHCIAVDPWFIVAQNPQQAR---LIRTAREV 290
Query: 293 NERQPLKLIELLKKHVPN--------LKDMKVGVLGLAFKPNTDDVRETRA 335
N+ +P +I+ +K V + ++K+ GLAFKPN DD+RE+ A
Sbjct: 291 NDHKPFWVIDQVKAAVADCLAATDKRASELKIACFGLAFKPNIDDLRESPA 341
>sp|Q04972|VIPA_SALTI VI POLYSACCHARIDE BIOSYNTHESIS PROTEIN VIPA/TVIB
>gi|1361287|pir||B36892 Vi polysaccharide biosynthetic
protein VipA - Salmonella typhi
>gi|475033|dbj|BAA03192.1| (D14156) WcdA protein
[Salmonella typhi] >gi|581779|emb|CAA47991.1| (X67785)
wcdA; ORF2 in citation [1] [Salmonella typhi]
Length = 425
Score = 128 bits (319), Expect = 1e-28
Identities = 109/360 (30%), Positives = 167/360 (46%), Gaps = 17/360 (4%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
+ ++IIG GYVGL + F K +V+ DV++ ++ + N E EEL +
Sbjct: 7 VKIAIIGLGYVGLPLAVEFGK-SRQVVGFDVNKKRILELKNGVDVNLETTEEELRE---A 62
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVK 120
+Y + E I + ITV TP DLT + A++ +G L D IVV +
Sbjct: 63 RYLKFTSEIEKIKECNFYIITVPTPINTYKQPDLTPLIKASETVGTVLNRGD---IVVYE 119
Query: 121 STVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDER 180
STV PG TE PIL + SG QDF + +PE + G N +I G +
Sbjct: 120 STVYPGCTEEECVPILARMSGMTFNQDFYVGYSPERINPGDKKHRLTNIKKITSG-STAQ 178
Query: 181 TKKVLEKLYEPFNAPKLFT--DIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSWK 238
++++++Y+ + + IK AE K N I+ NE+ I +L ID+
Sbjct: 179 IAELIDEVYQQIISAGTYKAESIKVAEAAKVIENTQRDLNIALVNELAIIFNRLNIDTEA 238
Query: 239 VFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQ-- 296
V G P FR G+ GG C D L K++ +G P I+ A ++N+
Sbjct: 239 VLRAAGSKWNFLP--FRPGL-VGGHCIGVDPYYLTHKSQGIGYYPEIILAGRRLNDNMGN 295
Query: 297 --PLKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDP 354
+LI+ + K N++ V +LG FK N D+R TR V+K+L + KV +DP
Sbjct: 296 YVSEQLIKAMIKKGINVEGSSVLILGFTFKENCPDIRNTRIIDVVKELGKYSCKVDIFDP 355
>emb|CAA78147.1| (Z12159) uridine diphosphate glucose dehydrogenase [Streptococcus
pneumoniae] >gi|1586508|prf||2204223D UDP-Glucose
dehydrogenase [Streptococcus pneumoniae]
Length = 394
Score = 128 bits (318), Expect = 1e-28
Identities = 110/407 (27%), Positives = 193/407 (47%), Gaps = 49/407 (12%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
M ++I GSGYVGL + + + V +DV + KV INN + PI +E +E+ + E +
Sbjct: 1 MKIAIAGSGYVGLSLAV-LLAQHHEVKVIDVIKDKVESINNRKSPIKDEAIEKYLVEKEL 59
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIG-KALKEKDNFHIVVV 119
A+ + A + D+ + + TP+ D +DL ++ E K E ++ +V+
Sbjct: 60 NLEASLD--PAHVYKDVEYAIIATPTNYD--VDLNQFDTSSVEAAIKTCMEYNDTCTIVI 115
Query: 120 KSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQ-- 177
KST+ EG + + +K++ + + +PEFLRE AL D L P RIV+G
Sbjct: 116 KSTI----PEGYTKEVRDKFNTDR------IIFSPEFLRESKALYDNLYPSRIVVGTDLD 165
Query: 178 -DERTKK------VLEKLYEPFNAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICK 230
E TK+ +L+ P L AE+ K SN +LAT++ + NEI +
Sbjct: 166 DSELTKRAWQFADLLKGGAIKEEVPILVVAFNEAEVAKLFSNTYLATRVRYFNEIDTYSE 225
Query: 231 KLGIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVL 290
++ + + V D RI ++ G+GG C PKD K L ++ E+ ++ AV+
Sbjct: 226 VKELNPKTIIDIVCYDPRIGSYYNNPSFGYGGYCLPKDTKQLKASFRDVPEN--LITAVV 283
Query: 291 QVNERQPLKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVI 350
Q N+ + + + P++ VG+ L K ++D+ R + V+++L G +++
Sbjct: 284 QSNKTRKDYIAGAILAKQPSV----VGIYRLIMKSDSDNFRSSAVKGVMERLDNYGKEIV 339
Query: 351 AYDP-------------KAMENFKRFYPDVGRQISYANSAEEVLREV 384
Y+P K+++ FK I AN + LR++
Sbjct: 340 IYEPTIECDTFMGYRVIKSLDEFKNI-----SDIVVANRMNDDLRDI 381
>gb|AAF23997.1| (AF035937) WbpO [Pseudomonas aeruginosa]
Length = 422
Score = 127 bits (316), Expect = 2e-28
Identities = 101/360 (28%), Positives = 172/360 (47%), Gaps = 17/360 (4%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
+ V+++G GYVGL + F K V+ D+++ ++ + E EL + +
Sbjct: 4 LKVAVVGLGYVGLPLAVEFGKK-RTVVGFDINQGRIAELRQGIDSTLEVDAAELKEASEL 62
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVK 120
+ T N ++ + ++ +TV TP DLT + A++ IGK LK+ D IV+ +
Sbjct: 63 SF--TFNLQD-LQKCNVFIVTVPTPIDEHKQPDLTPLVKASESIGKVLKKGD---IVIYE 116
Query: 121 STVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDER 180
STV PG TE P+LEK+SG + +DF +PE + G + ++ G E
Sbjct: 117 STVYPGATEEDCVPVLEKFSGLRFNEDFFAGYSPERINPGDKEHRVSSIKKVTSGSTPE- 175
Query: 181 TKKVLEKLYEPF--NAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSWK 238
++++ LY + IK AE K N I+ NE+ I ++GID+
Sbjct: 176 IAELVDSLYREIITAGTHKASSIKVAEAAKVIENTQRDLNIALINELAIIFNRMGIDTEA 235
Query: 239 VFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQPL 298
V + G P FR G+ GG C D L KA+ +G P I+ A ++N+
Sbjct: 236 VLKAAGTKWNFMP--FRPGL-VGGHCIGVDPYYLTHKAQSIGYHPEIILAGRRLNDGMGA 292
Query: 299 ----KLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDP 354
+L++ + K ++ +V ++GL FK N D+R T+ ++++L E +V +DP
Sbjct: 293 YVVSQLVKAMLKRRIHVDGARVLLMGLTFKENCPDLRNTKVVDIVRELAEYNIQVDVFDP 352
>pir||T44509 Vi polysaccharide biosynthetic protein [imported] - Plesiomonas
shigelloides >gi|6009648|dbj|BAA85006.1| (AB025970)
ORF1P [Plesiomonas shigelloides]
>gi|10442655|gb|AAG17408.1|AF285970_2 (AF285970) WbgT
[Plesiomonas shigelloides]
Length = 437
Score = 125 bits (312), Expect = 7e-28
Identities = 106/358 (29%), Positives = 166/358 (45%), Gaps = 17/358 (4%)
Query: 3 VSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKGKY 62
+ IIG GYVGL + F K + F D+++ ++ + N E EL++ K Y
Sbjct: 21 IGIIGLGYVGLPLAVEFGKKVTTIGF-DINKSRIDELRNGHDSTLECSNLELLEATKLTY 79
Query: 63 YATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVKST 122
+ +A+ ++ +TV TP DLT + A++ +GK +K+ D +++ +ST
Sbjct: 80 ACS---LDALKECNVFIVTVPTPIDKHKQPDLTPLIKASETLGKIIKKGD---VIIYEST 133
Query: 123 VLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDERTK 182
V PG TE P++EK SG K DF +PE + G N ++ G + +
Sbjct: 134 VYPGATEEDCIPVVEKVSGLKFNIDFFAGYSPERINPGDKEHRVTNILKVTSGSTPDVAE 193
Query: 183 KV--LEKLYEPFNAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSWKVF 240
V L KL K + IK AE K N I+ NE+ I KLGID+ +V
Sbjct: 194 YVDQLYKLIITVGTHKA-SSIKVAEAAKVIENTQRDVNIALINELSIIFNKLGIDTLEVL 252
Query: 241 EGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQ---- 296
E G P FR G+ GG C D L KA+ +G P ++ A ++N+
Sbjct: 253 EAAGTKWNFLP--FRPGL-VGGHCIGVDPYYLTHKAQSVGYHPEMILAGRRLNDSMGQYV 309
Query: 297 PLKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDP 354
+L++ + K ++ V V+GL FK N D+R T+ +I +L E + DP
Sbjct: 310 VSQLVKKMLKQRIQVEGANVLVMGLTFKENCPDLRNTKVIDIISELKEYNINIDIIDP 367
>pir||T44520 lipopolysaccharide biosynthesis protein [imported] - Shigella
sonnei >gi|6009797|dbj|BAA85071.1| (AB028135) ORF1S
[Shigella sonnei] >gi|10442666|gb|AAG17418.1|AF285971_2
(AF285971) WbgT [Shigella sonnei]
Length = 437
Score = 125 bits (312), Expect = 7e-28
Identities = 106/358 (29%), Positives = 166/358 (45%), Gaps = 17/358 (4%)
Query: 3 VSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKGKY 62
+ IIG GYVGL + F K + F D+++ ++ + N E EL++ K Y
Sbjct: 21 IGIIGLGYVGLPLAVEFGKKVTTIGF-DINKSRIDELRNGHDSTLECSNLELLEATKLTY 79
Query: 63 YATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVKST 122
+ +A+ ++ +TV TP DLT + A++ +GK +K+ D +++ +ST
Sbjct: 80 ACS---LDALKECNVFIVTVPTPIDKHKQPDLTPLIKASETLGKIIKKGD---VIIYEST 133
Query: 123 VLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDERTK 182
V PG TE P++EK SG K DF +PE + G N ++ G + +
Sbjct: 134 VYPGATEEDCIPVVEKVSGLKFNIDFFAGYSPERINPGDKEHRVTNILKVTSGSTPDVAE 193
Query: 183 KV--LEKLYEPFNAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSWKVF 240
V L KL K + IK AE K N I+ NE+ I KLGID+ +V
Sbjct: 194 YVDQLYKLIITVGTHKA-SSIKVAEAAKVIENTQRDVNIALINELSIIFNKLGIDTLEVL 252
Query: 241 EGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQ---- 296
E G P FR G+ GG C D L KA+ +G P ++ A ++N+
Sbjct: 253 EAAGTKWNFLP--FRPGL-VGGHCIGVDPYYLTHKAQSVGYHPEMILAGRRLNDSMGQYV 309
Query: 297 PLKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDP 354
+L++ + K ++ V V+GL FK N D+R T+ +I +L E + DP
Sbjct: 310 VSQLVKKMLKQRIQVEGANVLVMGLTFKENCPDLRNTKVIDIISELKEYNINIDIIDP 367
>gb|AAD40718.1|AF048749_14 (AF048749) putative UDP-glucose-6 dehydrogenase [Bacteroides
fragilis]
Length = 425
Score = 118 bits (293), Expect = 1e-25
Identities = 108/410 (26%), Positives = 182/410 (44%), Gaps = 20/410 (4%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
+ +++IG GYVGL F + F D+++ +V +N+ E + L + +
Sbjct: 4 LKIAVIGLGYVGLPLARLFSTKYECIGF-DLNQSRVDALNSGHDMTLEVSDDLLRKALEN 62
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVK 120
+ T+N E I N + + V TP + DLT + A+ +GK + + D IVV +
Sbjct: 63 GFKCTSNIDE-ISNCNFYVVAVPTPVDLNNRPDLTPLIGASTTVGKVISKGD---IVVYE 118
Query: 121 STVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDER 180
STV PG TE P++E+ SG DF +PE + G ++ G E
Sbjct: 119 STVYPGVTEEECLPVVEEVSGLTYNVDFYAGYSPERINPGDKEHTVEKIKKVTSGSTPE- 177
Query: 181 TKKVLEKLYEP--FNAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSWK 238
+++ +Y N IK AE K N+ I+F NE+ I +GID+
Sbjct: 178 IADIVDSVYNSVLVNGTHKAPSIKVAEASKIIENSQRDVNIAFMNELSKIFNAMGIDTND 237
Query: 239 VFEGVGLDHRISPHFFRSGIGF-GGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQ- 296
V E +F + G GG C D LI+KA+ G P I+ A ++N+
Sbjct: 238 VIEAASSKW----NFIKLKPGLVGGHCISVDPYYLIQKAQVYGVLPRIMSAARRLNDGMG 293
Query: 297 ---PLKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYD 353
++I L+ K +KD K+ +LG FK + D+R T+ + L E + + YD
Sbjct: 294 DYVANQVIRLMNKKGILVKDSKILLLGFTFKEDCPDIRNTKVIDIYSTLHEYTSDITVYD 353
Query: 354 PKAMENFKRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFESLDYSG 403
A N + + G I A + ++ + D +++ ++F ++ G
Sbjct: 354 --AWANSAKVAHEYGISILTA-GLDNLVGQFDAVVLCVGHKEFRHMNIRG 400
>pir||T44842 probable UDPglucose 6-dehydrogenase (EC 1.1.1.22) [imported] -
Acinetobacter lwoffii >gi|6010003|emb|CAB57210.1|
(AJ243431) putative UDP-glucose dehydrogenase
[Acinetobacter lwoffii]
Length = 416
Score = 117 bits (290), Expect = 3e-25
Identities = 73/270 (27%), Positives = 133/270 (49%), Gaps = 15/270 (5%)
Query: 154 PEFLREGVALKDFLNPDRIVIGVQDERTKKVLEKL---YEPFNAPKLFTDIKTAEMIKYA 210
P+ ++EG AL+ F ++++G + ++ +++L + PF LF + AE K +
Sbjct: 133 PDIIQEGNALQSFTQAKQLIVGFTEPSAQQKVKELLRPFFPFEQQFLFMPVLDAEFTKLS 192
Query: 211 SNAFLATKISFANEIGNICKKLGIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLK 270
+ LAT+I N++ + +KLGID V +G+ D+RI + G GFGG F D+
Sbjct: 193 ISGMLATRI---NDLAVVAEKLGIDITSVRQGMAADNRIGTAYLSPGAGFGGENFSHDVL 249
Query: 271 ALIKKAEELGEDPIILKAVLQVNERQPLKLI-ELLKKHVPNLKDMKVGVLGLAFKPNTDD 329
L G +L V ++NE+Q L +L + +L + + G +FK NT
Sbjct: 250 TLANTVANTGVKSQLLAQVWEINEQQKEILFRKLWNYYHGDLHGKTIAIWGASFKENTSS 309
Query: 330 VRETRAYIVIKKLLEEGAKVIAYDPKAMENFKRFYPDVGRQISYANSAEEVLREVDVILI 389
++ + ++++K L +G KV +DP+A+E + Y + E L + +
Sbjct: 310 IQHSPIHLMLKALWAQGVKVQLHDPQALEEIQMIYGQ-RDDLILCQQQYEALENAHGLCV 368
Query: 390 LTEWRDFESLDY-------SGKIVIDGRRV 412
LT W+ + S D+ + +V+DGR +
Sbjct: 369 LTAWKQYWSPDFKQMMQRMAHPLVLDGRNI 398
>pir||A83252 probable UDP-glucose/GDP-mannose dehydrogenase WbpA PA3159
[imported] - Pseudomonas aeruginosa (strain PAO1)
>gi|1545847|gb|AAC45852.1| (U50396) WbpA [Pseudomonas
aeruginosa] >gi|9949274|gb|AAG06547.1|AE004739_9
(AE004739) probable UDP-glucose/GDP-mannose
dehydrogenase WbpA [Pseudomonas aeruginosa]
Length = 436
Score = 116 bits (289), Expect = 4e-25
Identities = 115/419 (27%), Positives = 192/419 (45%), Gaps = 24/419 (5%)
Query: 3 VSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKGKY 62
+ I+G GYVGL + + +G V+ +D+D+ KV +N Q I ++ + +
Sbjct: 18 IGIVGLGYVGLPLMLRYNAIGFDVLGIDIDDVKVDKLNAGQCYIEHIPQAKIAKARASGF 77
Query: 63 YATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVKST 122
AT ++ + D + V TP D+++V N + L+ +V ++ST
Sbjct: 78 EATTDFSR-VSECDALILCVPTPLNKYREPDMSFVINTTDALKPYLRVGQ---VVSLEST 133
Query: 123 VLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDERTK 182
PGTTE + P +++ G +D L +PE RE +F R + V T
Sbjct: 134 TYPGTTEEELLPRVQE-GGLVVGRDIYLVYSPE--REDPGNPNF--ETRTIPKVIGGHTP 188
Query: 183 KVLE---KLYEP-FNAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSWK 238
+ LE LYE + + K AEM K N A I NE+ + ++GID ++
Sbjct: 189 QCLEVGIALYEQAIDRVVPVSSTKAAEMTKLLENIHRAVNIGLVNEMKIVADRMGIDIFE 248
Query: 239 VFEGVGLD-HRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQP 297
V + +P++ G G GG C P D L KA E G ++ +VN+ P
Sbjct: 249 VVDAAATKPFGFTPYY--PGPGLGGHCIPIDPFYLTWKAREYGLHTRFIELSGEVNQAMP 306
Query: 298 L----KLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYD 353
KL++ L + LK +V VLG+A+K N DD+RE+ + + I +L+E ++AY
Sbjct: 307 EYVLGKLMDGLNEAGRALKGSRVLVLGIAYKKNVDDMRESPS-VEIMELIEAKGGMVAYS 365
Query: 354 PKAMENFKRFYPDVGRQISYANSAEEVLREVDVILILTEWR--DFESLDYSGKIVIDGR 410
+ F + S +AE + R D +++ T+ D+E + K+V+D R
Sbjct: 366 DPHVPVFPKMREHHFELSSEPLTAENLAR-FDAVVLATDHDKFDYELIKAEAKLVVDSR 423
>gb|AAA84869.1| (U34305) ORF1; Method: conceptual translation supplied by author
[Shigella sonnei]
Length = 416
Score = 116 bits (288), Expect = 5e-25
Identities = 103/358 (28%), Positives = 166/358 (45%), Gaps = 18/358 (5%)
Query: 3 VSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKGKY 62
+ IIG GYVGL + F K + F D+++ ++ + N E EL++ K Y
Sbjct: 10 IGIIGLGYVGLPLAVEFGKKVTTIGF-DINKSRIDELRNGHDSTLECSNLELLEATKLTY 68
Query: 63 YATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVKST 122
+ +A+ ++ +TV P DLT + A++ +GK +K+ D +++ +ST
Sbjct: 69 ACS---LDALKECNVFIVTVPAPIDKHKQPDLTPLIKASETLGKIIKKGD---VIIYEST 122
Query: 123 VLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDERTK 182
V PG TE P++EK SG K DF +PE + G N ++ G + +
Sbjct: 123 VYPGATEEDCIPVVEKVSGLKFNIDFFAGYSPERINPGDKEHRVTNILKVASGSTPDVAE 182
Query: 183 KV--LEKLYEPFNAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSWKVF 240
V L KL K + IK E ++ N I+ NE+ I KLGID+ +V
Sbjct: 183 YVDQLYKLIITVGTHKA-SSIK-VERLQSNVNTQRDVNIALINELSIIFNKLGIDTLEVL 240
Query: 241 EGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQ---- 296
E G + P FR G+ GG C D L KA+ +G P ++ A ++N+
Sbjct: 241 EAAGTKWNLLP--FRPGL-VGGHCIGVDPYYLTHKAQSVGYHPEMILAGRRLNDSMGQYV 297
Query: 297 PLKLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDP 354
+L++ + K ++ V V+GL FK N D+R T+ +I +L E + DP
Sbjct: 298 VSQLVKKMLKQRIQVEGANVLVMGLTFKENCPDLRNTKVIDIISELKEYNINIDIIDP 355
>pir||S69821 NDP-sugar dehydrogenase homolog lmbL - Streptomyces lincolnensis
>gi|581693|emb|CAA55758.1| (X79146) lmbL [Streptomyces
lincolnensis]
Length = 436
Score = 115 bits (284), Expect = 1e-24
Identities = 105/415 (25%), Positives = 187/415 (44%), Gaps = 27/415 (6%)
Query: 3 VSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEF--KG 60
V++ G ++G G + G V+ + E R A PP E G+ E+++ +G
Sbjct: 8 VAVCGLWHLGSTAAAGLLTHGRAVVAYEPQEHCGRRAA-ATPPTGEPGVGEVLRRGLREG 66
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVK 120
+ + E N+ + + + DG +D + A + ++
Sbjct: 67 RLRVADALAEWARNA-LCVLAYDSAVDADGGVDDARLAQAVAAFARHAPAGATLAVL--- 122
Query: 121 STVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDER 180
+ +P T+ R L + D L PE LR G A+ DF+ P R+V+G ++
Sbjct: 123 -SQVPAHTQCAWRRTLLAHR-----PDVNLVHIPENLRLGRAMDDFVAPARLVVGAEERC 176
Query: 181 TKKVLEKLYEPFNAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSWKVF 240
T + + P P T + AE++K+A+NA+L +SF NE+G + LG D V
Sbjct: 177 TAERTARSLFPRATPAYVT-LTEAELVKHATNAYLGMCVSFGNELGWLAAHLGADPQVVA 235
Query: 241 EGVGLDHRISPHF-FRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQPLK 299
+ D R++ G F G+ +DL AL + + G P VL VN+R
Sbjct: 236 RLLKADPRVADAAPLLPGAAFSGATLRRDLVALSRIGAKWGR-PEFFDTVLTVNDRHAAF 294
Query: 300 LIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDPKAMEN 359
++LL + NLKD ++ + GL +K +R++ +++ LL +GA+V+AYDP A +
Sbjct: 295 PLDLLGAELGNLKDRRIALAGLTYKAGHATLRDSLPLRLVRTLLTDGAEVVAYDPVAED- 353
Query: 360 FKRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFESLDYSG-----KIVIDG 409
DVG + A + + + + L+ + + D++G ++V+DG
Sbjct: 354 ---LPDDVGAR--RAATLADAVPAPNACLVAAALPELDGADWAGLRPAARLVVDG 403
>pir||S44959 lmbL protein - Streptomyces lincolnensis
Length = 436
Score = 115 bits (284), Expect = 1e-24
Identities = 105/415 (25%), Positives = 187/415 (44%), Gaps = 27/415 (6%)
Query: 3 VSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEF--KG 60
V++ G ++G G + G V+ + E R A PP E G+ E+++ +G
Sbjct: 8 VAVCGLWHLGSTAAAGLLTHGRAVVAYEPQEHCGRRAA-ATPPTGEPGVGEVLRRGLREG 66
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVK 120
+ + E N+ + + + DG +D + A + ++
Sbjct: 67 RLRVADALAEWARNA-LCVLAYDSAVDADGGVDDARLAQAVAAFARHAPAGATLAVL--- 122
Query: 121 STVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDER 180
+ +P T+ R L + D L PE LR G A+ DF+ P R+V+G ++
Sbjct: 123 -SQVPAHTQCAWRRTLLAHR-----PDVNLVHIPENLRLGRAMDDFVAPARLVVGAEERC 176
Query: 181 TKKVLEKLYEPFNAPKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSWKVF 240
T + + P P T + AE++K+A+NA+L +SF NE+G + LG D V
Sbjct: 177 TAERTARSLFPRATPAYVT-LTEAELVKHATNAYLGMCVSFGNELGWLAAHLGADPQVVA 235
Query: 241 EGVGLDHRISPHF-FRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQPLK 299
+ D R++ G F G+ +DL AL + + G P VL VN+R
Sbjct: 236 RLLKADPRVADAAPLLPGAAFSGATLRRDLVALSRIGAKWGR-PEFFDTVLTVNDRHAAF 294
Query: 300 LIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDPKAMEN 359
++LL + NLKD ++ + GL +K +R++ +++ LL +GA+V+AYDP A +
Sbjct: 295 PLDLLGAELGNLKDRRIALAGLTYKAGHATLRDSLPLRLVRTLLTDGAEVVAYDPVAED- 353
Query: 360 FKRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFESLDYSG-----KIVIDG 409
DVG + A + + + + L+ + + D++G ++V+DG
Sbjct: 354 ---LPDDVGAR--RAATLADAVPAPNACLVAAALPELDGADWAGLRPAARLVVDG 403
>pir||C82713 polysaccharide biosynthetic protein XF1183 [imported] - Xylella
fastidiosa (strain 9a5c)
>gi|9106151|gb|AAF83993.1|AE003952_4 (AE003952)
polysaccharide biosynthetic protein [Xylella fastidiosa]
Length = 433
Score = 111 bits (274), Expect = 2e-23
Identities = 106/360 (29%), Positives = 167/360 (45%), Gaps = 17/360 (4%)
Query: 3 VSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKGKY 62
++++G GYVGL + F + + F D+D +V+ + E LEEL +Y
Sbjct: 17 IAVVGLGYVGLPLAVAFGRQRPTLGF-DIDICRVQQLCAGHDITCEIELEELQAARHLRY 75
Query: 63 YATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVKST 122
+++ RE + + I ITV TP DL +++A+ + LK D +V+ +ST
Sbjct: 76 --SSDPRE-LSDCQIFIITVPTPIDVAEQPDLGPLRSASMLVASVLKPGD---LVIYEST 129
Query: 123 VLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDERTK 182
V PGTTE V P+LE SG DF +PE + G + + +I+ G + T
Sbjct: 130 VYPGTTEEVCVPLLEVGSGLCFNVDFHCGYSPERINPGDRKRRLQDICKIISGSTPDIT- 188
Query: 183 KVLEKLYEPFNAPKLF--TDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSWKVF 240
V++ LY + I+ AE K N I+ NE+ I +LGID+ V
Sbjct: 189 AVVDALYSQIIVAGTWCAPSIRVAEAAKVVENIQRDVNIALVNELALIFNRLGIDTLDVL 248
Query: 241 EGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNERQPL-- 298
E P FR G+ GG C D L+ K+E +G P ++ +VN R
Sbjct: 249 EAAETKWNFLP--FRPGL-VGGHCIGVDPYYLLHKSESVGYYPDLIHTARRVNSRVSWHV 305
Query: 299 --KLIELLKKHVPNLKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDPKA 356
+++ LL + + V VLG+ FK + D+R +RA +++ GA+V DP A
Sbjct: 306 VDRVVALLGELSVPMTRAVVLVLGVTFKEDCPDLRNSRALDLVRMFRTLGAQVDVCDPCA 365
>emb|CAB82012.1| (AL161755) putative nucleotide-sugar dehydrogenase [Streptomyces
coelicolor A3(2)]
Length = 405
Score = 108 bits (268), Expect = 1e-22
Identities = 92/342 (26%), Positives = 155/342 (44%), Gaps = 31/342 (9%)
Query: 80 ITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVKSTVLPGTTEGVIRPILEKY 139
I TP DG +DLT V+ AA+ + ++ V+++S V PGTTE +RP+LE+
Sbjct: 73 ICAPTPPGADGGLDLTQVEAAARTLAAHMRPHTT---VILESPVRPGTTEDFLRPLLEQG 129
Query: 140 SGKKAFQDFGLAMNPEFLREGVALKDF--LNPDRIVIGVQDERTKKVLEKLYEPFNAPKL 197
SG +A +DF LA +P + G +DF N +++ G+ T+ +
Sbjct: 130 SGLRAGRDFHLAYSPSRVDPG--NRDFTPANTPKVIGGLTPACTESAAAFYSRLTDKVVR 187
Query: 198 FTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDSWKVFEGVGLDHRISPHFFRSG 257
+ AE ++ F I+ NE+ +C LG+D W V H FR G
Sbjct: 188 ARGPREAETVQLLETNFRHVNIALVNEMAVLCDDLGVDLWDVLR-CAETKPFGFHAFRPG 246
Query: 258 IGFGGSCFPKDLKALIKKAEELGEDPIILKAV---LQVNERQPLKLIE----LLKKHVPN 310
G GG +DL G P L+ V QVN + P +++ LL +H +
Sbjct: 247 PGVGGHSVAQDL---------TGRAPHSLRMVELAQQVNAQMPRYVVQRAAALLNEHGKS 297
Query: 311 LKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDPKAMENFKRFYPDVGRQ 370
+ ++ +LG+ +K + D + T A + +L+ GA V +DP + R
Sbjct: 298 ARGARILLLGVTYKADLADQQATPAEEIATRLMSMGAAVSYHDPHIPS-----WNVADRP 352
Query: 371 ISYANSAEEVLREVDVILILTEWR--DFESLDYSGKIVIDGR 410
+ A+S E + D+ ++L + R D + L ++++D R
Sbjct: 353 VPRADSLYEAAADADLTILLQQHRTYDLQGLSVKAQLLLDTR 394
>gb|AAC05135.1| (AF049126) UDP glucose 6-dehydrogenase [Homo sapiens]
Length = 175
Score = 100 bits (246), Expect = 4e-20
Identities = 56/156 (35%), Positives = 88/156 (55%), Gaps = 3/156 (1%)
Query: 203 TAEMIKYASNAFLATKISFANEIGNICKKLGIDSWKVFEGVGLDHRISPHFFRSGIGFGG 262
++E+ K A+NAFLA +IS N I +C+ G D +V +G+D RI F ++ +GFGG
Sbjct: 2 SSELSKLAANAFLAQRISSINSISALCEATGADVEEVATAIGMDQRIGNKFLKASVGFGG 61
Query: 263 SCFPKDLKALIKKAEELG--EDPIILKAVLQVNERQPLKLIELLKKHVPN-LKDMKVGVL 319
SCF KD+ L+ E L E + V+ +N+ + + + N + D K+ +L
Sbjct: 62 SCFQKDVLNLVYLCEALNLPEVARYWQQVIDMNDYXRRRFASRIIDSLFNTVTDKKIAIL 121
Query: 320 GLAFKPNTDDVRETRAYIVIKKLLEEGAKVIAYDPK 355
G A K +T D RE+ + + K L++EGA + YDPK
Sbjct: 122 GFAVKKDTGDTRESSSIYISKYLMDEGAHLHIYDPK 157
>gb|AAC12870.1| (AF044332) UDP-ManNAc dehydrogenase; RffD [Pectobacterium
carotovorum subsp. atrosepticum]
Length = 287
Score = 86.6 bits (211), Expect = 5e-16
Identities = 71/279 (25%), Positives = 132/279 (46%), Gaps = 24/279 (8%)
Query: 147 DFGLAMNPEFLREGVALKDFLNPDRIVIGVQDERTKKVLEKLYEPF-NAPKLFTDIKTAE 205
D +A PE + G + + + DR++ G+ + + E LY F + T+ +TAE
Sbjct: 18 DINIAYCPERVLPGQVVVELIKNDRVIGGMTPVCSARASE-LYNIFLEGECVVTNSRTAE 76
Query: 206 MIKYASNAFLATKISFANEIGNICKKLGIDSWKVFEGVGLDHRISPHFFRSGIGFGGSCF 265
M K N+F I+FANE+ IC + I+ W++ R+ + + G G GG C
Sbjct: 77 MCKLTENSFRDVNIAFANELSLICAEQNINVWELIRLANRHPRV--NILQPGPGVGGHCI 134
Query: 266 PKDLKALIKKAEELGEDPIILKAVLQVNERQPLKLIELLKKHVPN--------LKDMKVG 317
D ++ + + ++ VN+ +PL +++ +K V + ++ V
Sbjct: 135 AVDPWFIVAQNPQQAR---LIHTARLVNDGKPLWVVDRVKAAVADYLAQTDKRASEVTVA 191
Query: 318 VLGLAFKPNTDDVRETRAYIVIKKLLEEGAKV-IAYDPKAMENFKRFYPDVGRQISYANS 376
GLAFKP+ DD+RE+ A + + + V + +P N K + Q+ ++
Sbjct: 192 CFGLAFKPDIDDLRESPAVGITSMIAQWNTGVTLVVEP----NVKHLPSVLAGQVKLVDT 247
Query: 377 AEEVLREVDVILILTEWRDFESL---DYSGKIVIDGRRV 412
+ L+E DV+++L + R F+++ D + VID + V
Sbjct: 248 S-SALKEADVLVMLVDHRQFKAINPDDVKQQWVIDTKGV 285
>gb|AAD45294.1|AF156256_2 (AF156256) putative dehydrogenase [Vibrio anguillarum]
Length = 237
Score = 79.2 bits (192), Expect = 8e-14
Identities = 71/239 (29%), Positives = 110/239 (45%), Gaps = 16/239 (6%)
Query: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEEGLEELMQEFKG 60
+ + IIG GYVGL + F K + V F D+++ +V +++ E EEL
Sbjct: 6 VKIGIIGLGYVGLPLAVEFGKKFSTVGF-DINQKRVAELHSGIDLTLECSEEELRSAPLL 64
Query: 61 KYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIVVVK 120
Y + E I + + +TV TP + T DL +K A++ + K + D IVV +
Sbjct: 65 SY---THQLEEIKDCNFYIVTVPTPITDEKTPDLNPLKKASEALAKVVSHGD---IVVFE 118
Query: 121 STVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQDER 180
STV PG TE V PI+EK SG +DF +PE + G D +N ++ +
Sbjct: 119 STVYPGATEEVCLPIIEKNSGLVFNRDFFAGYSPERINPG----DKVNRLTTIMKITSGS 174
Query: 181 TKKVLEKLYEPFNA-----PKLFTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGI 234
T +V + + + +++ IK AE K N I+ NE I +LGI
Sbjct: 175 TPEVADFVDQVYSSIVTAGTHKAPSIKVAEAAKVIENTQRDLNIAVINEFAKIFNRLGI 233
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.319 0.140 0.403
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 160534066
Number of Sequences: 2977
Number of extensions: 7086295
Number of successful extensions: 18582
Number of sequences better than 1.0e-10: 113
Number of HSP's better than 0.0 without gapping: 66
Number of HSP's successfully gapped in prelim test: 47
Number of HSP's that attempted gapping in prelim test: 18047
Number of HSP's gapped (non-prelim): 115
length of query: 427
length of database: 189,106,746
effective HSP length: 56
effective length of query: 371
effective length of database: 155,591,474
effective search space: 57724436854
effective search space used: 57724436854
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 166 (69.1 bits)