BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB0771 (PAB0771) DE:UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE (EC 2.7.7.9) (UDP-GLUCOSE PYROPHOSPHORYLASE) (UDPGP) (ALPHA-D-GLUCOSYL-1-PHOSPHATE URIDYLYLTRANSFERASE) (URIDINE DIPHOSPHOGLUCOSE PYROPHOSPHORYLASE). (291 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||A75096 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7... 568 e-161 dbj|BAB07371.1| (AP001519) UTP-glucose-1-phosphate uridylyltrans... 325 3e-88 pir||G69892 UTP--glucose-1-phosphate uridylyltransferase homolog... 325 3e-88 pir||D69184 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7... 315 5e-85 gi|10956341 pXO1-94 [Bacillus anthracis] >gi|7474335|pir||F59102... 312 2e-84 sp|Q05852|GTAB_BACSU UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERAS... 306 2e-82 dbj|BAB07436.1| (AP001519) UTP-glucose-1-phosphate uridylyltrans... 303 2e-81 sp|Q58730|YD34_METJA PUTATIVE UTP--GLUCOSE-1-PHOSPHATE URIDYLYLT... 294 6e-79 gb|AAG24457.1|AF312223_1 (AF312223) putative UTP-glucose-1-phosp... 289 2e-77 emb|CAA06172.1| (AJ004869) UTP-glucose-1-phosphate uridylyltrans... 289 2e-77 sp|Q54713|HASC_STRPY UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERAS... 287 1e-76 emb|CAB90754.1| (AJ400707) putative UDP-glucose pyrophosphorylas... 284 8e-76 dbj|BAA28714.1| (AB001562) glucose-1-phosphate uridylyltransfera... 283 2e-75 sp|Q54800|CAPC_STRPN UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERAS... 282 4e-75 pir||H70446 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7... 280 1e-74 gb|AAC43313.1| (U15171) glucose-1-phosphate uridylyltransferase ... 280 2e-74 sp|P47691|GALU_MYCGE UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERAS... 278 6e-74 pir||E71913 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7... 272 4e-72 emb|CAB59678.1| (AL132674) UTP-glucose-1-phosphate uridylyltrans... 271 6e-72 pir||F64600 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7... 268 5e-71 sp|P75124|GALU_MYCPN UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERAS... 264 8e-70 pir||D81930 probable UTP--glucose-1-phosphate uridylyltransferas... 262 4e-69 pir||C81175 UTP--glucose-1-phosphate uridylyltransferase NMB0638... 259 2e-68 pir||A83394 UTP--glucose-1-phosphate uridylyltransferase PA2023 ... 255 5e-67 pir||H82325 UTP--glucose-1-phosphate uridylyltransferase VC0395 ... 253 2e-66 pir||F81300 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7... 248 7e-65 pir||JC4985 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7... 247 1e-64 pir||D82558 UTP-glucose-1-phosphate uridylyltransferase XF2432 [... 245 4e-64 gb|AAF61451.1|AF139598_1 (AF139598) UDPG-pyrophosphorylase [Acet... 243 1e-63 dbj|BAB06022.1| (AP001515) UTP-glucose-1-phosphate uridylyltrans... 238 6e-62 emb|CAA09328.1| (AJ010734) UDP-glucose pyrophosphorylase [Pseudo... 237 1e-61 gb|AAD19415.1| (AF102543) UTP-glucose-1-phosphate uridyltransfer... 236 2e-61 sp|Q59633|GALU_PSEAE UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERAS... 234 1e-60 pir||T44841 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7... 233 2e-60 sp|P42407|YTDA_BACSU PUTATIVE UTP--GLUCOSE-1-PHOSPHATE URIDYLYLT... 229 4e-59 sp|P44878|GALU_HAEIN UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERAS... 225 4e-58 gb|AAC28326.1| (AF053017) UTP-glucose-1-phosphate uridylyltransf... 222 4e-57 gb|AAG23691.1|AF297520_3 (AF297520) UDP-glucose pyrophosphorylas... 219 4e-56 pir||S39959 exoN protein - Rhizobium meliloti >gi|397573|emb|CAA... 210 2e-53 sp|P25520|GALU_ECOLI UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERAS... 209 3e-53 sp|P27897|CELA_ACEXY UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERAS... 208 8e-53 sp|P33696|EXON_RHIME UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERAS... 205 4e-52 pir||S78541 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7... 194 1e-48 sp|P78083|GALF_ECOLI UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERAS... 192 4e-48 pir||G70125 probable UTP--glucose-1-phosphate uridylyltransferas... 192 4e-48 sp|P37776|GALF_SHIFL UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERAS... 189 3e-47 emb|CAC11046.1| (AJ286776) UTP-glucose-1-phosphate uridylyltrans... 189 3e-47 emb|CAC11047.1| (AJ286777) UTP-glucose-1-phosphate uridylyltrans... 189 4e-47 emb|CAC11048.1| (AJ286778) UTP-glucose-1-phosphate uridylyltrans... 189 4e-47 sp|P26390|GALF_SALTY UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERAS... 188 6e-47 pir||S15298 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7... 188 6e-47 sp|Q48447|GALF_KLEPN UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERAS... 188 8e-47 pir||A56146 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7... 188 8e-47 emb|CAC11027.1| (AJ286782) UTP-glucose-1-phosphate uridylyltrans... 187 1e-46 emb|CAC11044.1| (AJ286774) UTP-glucose-1-phosphate uridylyltrans... 187 1e-46 emb|CAC11038.1| (AJ286767) UTP-glucose-1-phosphate uridylyltrans... 186 2e-46 emb|CAC11039.1| (AJ286768) UTP-glucose-1-phosphate uridylyltrans... 186 2e-46 emb|CAC11043.1| (AJ286772) UTP-glucose-1-phosphate uridylyltrans... 186 2e-46 emb|CAC11042.1| (AJ286771) UTP-glucose-1-phosphate uridylyltrans... 186 3e-46 emb|CAC11030.1| (AJ286773) UTP-glucose-1-phosphate uridylyltrans... 186 3e-46 emb|CAC11028.1| (AJ286780) UTP-glucose-1-phosphate uridylyltrans... 185 4e-46 emb|CAC11029.1| (AJ286781) UTP-glucose-1-phosphate uridylyltrans... 185 4e-46 emb|CAC11034.1| (AJ286763) UTP-glucose-1-phosphate uridylyltrans... 185 5e-46 emb|CAC11040.1| (AJ286769) UTP-glucose-1-phosphate uridylyltrans... 185 7e-46 emb|CAC11035.1| (AJ286764) UTP-glucose-1-phosphate uridylyltrans... 184 9e-46 emb|CAC11045.1| (AJ286775) UTP-glucose-1-phosphate uridylyltrans... 184 9e-46 emb|CAC11049.1| (AJ286779) UTP-glucose-1-phosphate uridylyltrans... 184 9e-46 emb|CAC11031.1| (AJ286760) UTP-glucose-1-phosphate uridylyltrans... 183 1e-45 emb|CAC11033.1| (AJ286762) UTP-glucose-1-phosphate uridylyltrans... 180 1e-44 pir||D70601 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7... 173 2e-42 pir||T45453 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7... 168 6e-41 gb|AAD50483.1|AF172324_1 (AF172324) GalF [Escherichia coli] 150 1e-35 gb|AAB49385.1| (M84642) putative glucose-1-phosphate uridylyltra... 128 7e-29 pir||A75596 probable glucose-1-phosphate thymidylyltransferase -... 120 3e-26 pir||T48866 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.... 114 1e-24 pir||A69079 glucose-1-phosphate thymidylyltransferase homolog - ... 113 2e-24 pir||A75098 glucose-1-phosphate thymidylyltransferase (grad-3) P... 113 3e-24 gb|AAK41110.1| UTP-glucose-1-phosphate uridylyltransferase [Sulf... 111 7e-24 emb|CAB57491.1| (Y18930) UDP-glucose pyrophosphorylase [Sulfolob... 111 7e-24 gi|11497938 glucose-1-phosphate thymidylyltransferase (graD-2) [... 111 1e-23 gb|AAG19459.1| (AE005038) glucose-1-phosphate thymidylyltransfer... 111 1e-23 pir||F71151 probable glucose-1-phosphate thymidylyltransferase -... 110 2e-23 gb|AAA67589.1| (M87049) similar to Streptomyces griseus StrD pro... 109 4e-23 pir||S30683 hypothetical protein o292 - Escherichia coli 106 2e-22 pir||G72325 glucose-1-phosphate thymidylyltransferase - Thermoto... 105 6e-22 pir||S76366 hypothetical protein - Synechocystis sp. (strain PCC... 104 1e-21 sp|P39629|SPSI_BACSU SPORE COAT POLYSACCHARIDE BIOSYNTHESIS PROT... 104 2e-21 gb|AAG18650.1| (AE004970) glucose-1-phosphate thymidylyltransfer... 103 2e-21 gb|AAK41126.1| Sugar phosphate nucleotydyl transferase [Sulfolob... 103 3e-21 emb|CAB57473.1| (Y18930) glucose-1-phosphate thymidylyltransfera... 103 3e-21 pir||T46521 probable dTDP-1-glucose synthase [imported] - Strept... 102 4e-21 gb|AAK41974.1| Sugar phosphate nucleotydyl transferase [Sulfolob... 101 1e-20 gb|AAD12972.1| (AF078135) RmlA [Leptospira borgpetersenii] 100 2e-20 gb|AAB50923.1| (L47163) glucose-1-phosphate thymidylyltransferas... 100 2e-20 sp|P55257|RFBA_YEREN GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (... 100 3e-20 gb|AAF59934.1| (AF237895) dTDP-D-glucose synthase [Streptomyces ... 100 3e-20 gb|AAD12523.1| (U02258) Homology to UDP pyrophosphorylase M76548... 99 4e-20 pir||T51105 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.... 99 5e-20 gb|AAB47843.1| (U61226) RfbA [Leptospira interrogans] >gi|581432... 99 7e-20 gb|AAD28517.1|AF126354_3 (AF126354) BlmD [Streptomyces bluensis] 99 7e-20 emb|CAA80332.1| (Z22611) OAC3 [Azorhizobium caulinodans] 98 2e-19 pir||C36864 probable glucose-1-phosphate thymidylyltransferase -... 98 2e-19 emb|CAA07386.1| (AJ006985) StrD [Streptomyces glaucescens] 97 2e-19 gb|AAD13545.1| (AF080235) NDP-hexose synthetase homolog [Strepto... 97 2e-19 gb|AAG18702.1| (AE004975) glucose-1-phosphate thymidylyltransfer... 96 5e-19 sp|P95778|RMLA_STRMU GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (... 94 1e-18 pir||G69101 mannose-1-phosphate guanyltransferase - Methanobacte... 93 3e-18 pir||S58687 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.... 93 4e-18 gb|AAC35920.1| (AF071085) putative glucose-1-phosphate thymidyl ... 92 5e-18 pir||T00103 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.... 92 5e-18 dbj|BAA94403.1| (AB041266) D-glucose-1-phosphate thymidylyltrans... 92 5e-18 gb|AAK43317.1| Sugar phosphate nucleotydyl transferase [Sulfolob... 92 5e-18 dbj|BAA19634.1| (AB002668) glucose-1-phosphate-thymidylyltransfe... 92 9e-18 gb|AAC68682.1| (AF079762) alpha-D-glucose-1-phosphate thymidylyl... 91 2e-17 emb|CAC12985.1| (AJ250327) glucose-1-phosphate thymidyltransfera... 90 2e-17 gb|AAD31799.1|AF128273_2 (AF128273) TDP-glucose synthase homolog... 90 2e-17 gb|AAC44969.1| (U09239) glucose-1-phosphate thymidyl transferase... 90 2e-17 dbj|BAB07082.1| (AP001518) spore coat polysaccharide synthesis (... 90 2e-17 dbj|BAA82533.1| (AB030032) glucose-1-phosphate thymidylyltransfe... 90 3e-17 pir||S49053 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.... 90 4e-17 pir||E71207 probable glucose-1-phosphate thymidylyltransferase -... 90 4e-17 sp|P37744|RBA1_ECOLI GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (... 89 8e-17 pir||I69650 glucose-1-phosphate thymidylyltransferase - Escheric... 89 8e-17 pir||D55213 rfbA protein - Shigella flexneri (strain 2a) >gi|294... 88 1e-16 pir||S78498 probable glucose-1-phosphate thymidylyltransferase (... 88 1e-16 gb|AAG09515.1|AF279619_3 (AF279619) glucose-1-phosphate thymidyl... 88 1e-16 pir||T30872 dNDP-glucose synthase - Streptomyces viridochromogen... 87 2e-16 pir||D75597 glucose-1-phosphate thymidylyltransferase - Deinococ... 87 2e-16 sp|P37779|RFBA_SHIFL GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (... 87 2e-16 gb|AAF73461.1|AF264025_12 (AF264025) putative dTDP-1-glucose syn... 87 3e-16 gb|AAG09511.1|AF279618_3 (AF279618) glucose-1-phosphate thymidyl... 87 3e-16 sp|P08075|STRD_STRGR GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (... 86 4e-16 pir||A26984 strD protein - Streptomyces griseus 86 4e-16 pir||D83000 glucose-1-phosphate thymidylyltransferase PA5163 [im... 86 4e-16 sp|P55253|RBA2_ECOLI GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (... 86 4e-16 sp|P55255|RFBA_NEIMB GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (... 86 5e-16 gb|AAG23610.1|AF244661_1 (AF244661) glucose-1-phosphate thymidyl... 85 7e-16 gb|AAC37050.1| (L09189) glucose-1-phosphate thymidyl transferase... 85 7e-16 pir||D64437 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.... 85 7e-16 emb|CAA77210.1| (Y18523) dTDP-glucose synthase [Actinoplanes sp.... 85 9e-16 gb|AAG23575.1|AF244626_1 (AF244626) glucose-1-P thymidylyltransf... 85 9e-16 gb|AAG09500.1|AF279615_3 (AF279615) glucose-1-phosphate thymidyl... 85 1e-15 sp|P55254|RFBA_SALAN GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (... 84 2e-15 emb|CAB01949.1| (Z79692) ExpA7 [Sinorhizobium meliloti] 84 2e-15 emb|CAB88884.1| (AL353861) putative mannose-1-phosphate guanyltr... 84 2e-15 gb|AAG09532.1|AF279623_3 (AF279623) glucose-1-phosphate thymidyl... 83 3e-15 gb|AAG09504.1|AF279616_3 (AF279616) glucose-1-phosphate thymidyl... 83 3e-15 sp|P26393|RFBA_SALTY GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (... 83 4e-15 gb|AAG09519.1|AF279620_3 (AF279620) glucose-1-phosphate thymidyl... 82 6e-15 gb|AAG09524.1|AF279621_3 (AF279621) glucose-1-phosphate thymidyl... 82 6e-15 emb|CAA11943.1| (AJ224437) GalU protein [Erwinia carotovora subs... 82 8e-15 gb|AAG09536.1|AF279624_3 (AF279624) glucose-1-phosphate thymidyl... 81 2e-14 gb|AAG09528.1|AF279622_3 (AF279622) glucose-1-phosphate thymidyl... 81 2e-14 gb|AAG09539.1|AF279625_3 (AF279625) glucose-1-phosphate thymidyl... 81 2e-14 gb|AAG18651.1| (AE004970) glucose-1-phosphate thymidylyltransfer... 81 2e-14 gb|AAK41040.1| Sugar phosphate nucleotydyl transferase [Sulfolob... 79 5e-14 emb|CAB57558.1| (Y18930) glucose-1-phosphate thymidylyltransfera... 79 5e-14 gb|AAF00210.1|AF164960_6 (AF164960) dNDP-glucose synthetase [Str... 78 9e-14 emb|CAC01394.1| (AJ131360) glucose-1-phosphate thymidyltransfera... 78 2e-13 pir||G75020 glucose-1-phosphate thymidylyltransferase (grad-2) P... 77 2e-13 gi|11497858 glucose-1-phosphate thymidylyltransferase (graD-1) [... 77 3e-13 dbj|BAA77382.1| (AB020570) GDP-mannose pyrophosphorylase [Candid... 76 3e-13 pir||A72589 probable glucose-1-phosphate thymidylyltransferase A... 75 1e-12 gi|6320148 mannose-1-phosphate guanyltransferase, GDP-mannose py... 74 2e-12 gb|AAA69677.1| (U24437) mannose-1-phosphate guanyltransferase [S... 73 4e-12 emb|CAC12604.1| (AL445067) mannose-1-phosphate guanyltransferase... 73 4e-12 pir||A55213 hypothetical protein 2.8, rfbB 5'-region - Shigella ... 72 7e-12 dbj|BAA15884.1| (D90841) UTP--glucose-1-phosphate uridylyltransf... 72 7e-12 >pir||A75096 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) PAB0771 [similarity] - Pyrococcus abyssi (strain Orsay) >gi|5458582|emb|CAB50070.1| (AJ248286) UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE (EC 2.7.7.9) (UDP-GLUCOSE PYROPHOSPHORYLASE) (UDPGP) (ALPHA-D-GLUCOSYL-1-PHOSPHATE URIDYLYLTRANSFERASE) (URIDINE DIPHOSPHOGLUCOSE PYROPHOSPHORYLASE). [Pyrococcus abyssi] Length = 291 Score = 568 bits (1449), Expect = e-161 Identities = 291/291 (100%), Positives = 291/291 (100%) Query: 1 MIRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKR 60 MIRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKR Sbjct: 1 MIRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKR 60 Query: 61 AIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVN 120 AIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVN Sbjct: 61 AIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVN 120 Query: 121 GEPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDL 180 GEPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDL Sbjct: 121 GEPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDL 180 Query: 181 YRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNE 240 YRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNE Sbjct: 181 YRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNE 240 Query: 241 ILAKRIEGERYDIGSKFGFVMANLKLSLRREELRNEVLKYLKSILKEISNE 291 ILAKRIEGERYDIGSKFGFVMANLKLSLRREELRNEVLKYLKSILKEISNE Sbjct: 241 ILAKRIEGERYDIGSKFGFVMANLKLSLRREELRNEVLKYLKSILKEISNE 291 >dbj|BAB07371.1| (AP001519) UTP-glucose-1-phosphate uridylyltransferase [Bacillus halodurans] Length = 297 Score = 325 bits (825), Expect = 3e-88 Identities = 157/288 (54%), Positives = 216/288 (74%), Gaps = 2/288 (0%) Query: 2 IRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRA 61 ++KA+IPAAGLGTR LP TK+ PKEMLPIVD+P I Y++EEA+++GIEDI+++TG+GKRA Sbjct: 3 VKKAIIPAAGLGTRFLPATKAQPKEMLPIVDKPTIQYIIEEAIESGIEDIIVVTGRGKRA 62 Query: 62 IEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNG 121 IED+FD+SFELE L+++ K + L EV+ I M +I+Y+RQK+ GLG AI A K + Sbjct: 63 IEDHFDKSFELEETLEKKNKSKLLEEVKAISSMTNIHYIRQKEANGLGHAIWCARKFIGN 122 Query: 122 EPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGII--EGELIEND 179 EPFAVLLGDDI+ S P +KQLI+V +R ++ V+GV+ VP E VS+YGI+ +G IE + Sbjct: 123 EPFAVLLGDDIVQSDVPCLKQLIDVFDRYHSSVVGVQEVPNEDVSKYGIVSPKGSEIEAN 182 Query: 180 LYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKN 239 + VEKP +EAPSN AI+GRY+L PEIFDIL PPG GEIQLTDA+++L Sbjct: 183 VIHAAGFVEKPKLEEAPSNYAIMGRYVLRPEIFDILENLPPGAGGEIQLTDAIKVLNESQ 242 Query: 240 EILAKRIEGERYDIGSKFGFVMANLKLSLRREELRNEVLKYLKSILKE 287 +LA +G RYD+G KFGF+ A + L+L+R++L +V +Y+K I ++ Sbjct: 243 VVLAYNFDGVRYDVGDKFGFIKATIDLALQRDDLSEDVAQYIKDIYEK 290 >pir||G69892 UTP--glucose-1-phosphate uridylyltransferase homolog yngB [imported] - Bacillus subtilis >gi|2634201|emb|CAB13701.1| (Z99113) similar to UTP-glucose-1-phosphate uridylyltransferase [Bacillus subtilis] Length = 297 Score = 325 bits (825), Expect = 3e-88 Identities = 159/290 (54%), Positives = 218/290 (74%) Query: 2 IRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRA 61 +RKAVIPAAGLGTR LP TK+ PKEMLPIVD+P I Y+VEEA ++GIEDILIITG+ KR+ Sbjct: 5 VRKAVIPAAGLGTRFLPATKAQPKEMLPIVDKPAIQYIVEEAAESGIEDILIITGRNKRS 64 Query: 62 IEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNG 121 IED+FDRS ELE+ L+E+GK E L+E+++I ++ +I+Y+RQK+PLGLG A+L AE + Sbjct: 65 IEDHFDRSAELEFNLREKGKTETLKEMQQIADLANIHYIRQKEPLGLGHAVLCAEHFIGD 124 Query: 122 EPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLY 181 EPFAVLLGDDI++S+ PA++QL++V + T V+GV+SV E VS+YGII + +Y Sbjct: 125 EPFAVLLGDDIMVSETPALRQLMDVYDVYGTEVVGVQSVLPEDVSKYGIINTSGSQGHVY 184 Query: 182 RIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNEI 241 + LVEKPSP+EAPS IA++GRY+L IF +L+ G EIQLTDAL+ + K I Sbjct: 185 EVNDLVEKPSPEEAPSEIAVMGRYVLNSSIFSVLKTIGRGAGNEIQLTDALREVCRKEPI 244 Query: 242 LAKRIEGERYDIGSKFGFVMANLKLSLRREELRNEVLKYLKSILKEISNE 291 A+ +EG RYDIG K G A+ ++ L R E+R+++L YL+ ++K + E Sbjct: 245 HARLLEGNRYDIGDKLGCFKASTEIGLMRPEMRSQLLAYLEDVIKRETKE 294 >pir||D69184 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) MTH634 [similarity] - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2621716|gb|AAB85140.1| (AE000844) UTP--glucose-1-phosphate uridylyltransferase [Methanobacterium thermoautotrophicum] Length = 285 Score = 315 bits (798), Expect = 5e-85 Identities = 158/283 (55%), Positives = 208/283 (72%), Gaps = 4/283 (1%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 KAVIPAAGLGTR LP TK+ PKEMLP+ D+P I YVVEEAV +GI+DILIITGKGKR+IE Sbjct: 2 KAVIPAAGLGTRFLPATKAQPKEMLPVFDKPTIQYVVEEAVASGIDDILIITGKGKRSIE 61 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGE- 122 D+FDRSFELEY+L++ K+ L EVE I ++ DIY+VRQK+ GLGDAI A KH++GE Sbjct: 62 DHFDRSFELEYFLRKNNKMNYLDEVEAISDLADIYFVRQKEQKGLGDAIYCARKHIDGED 121 Query: 123 PFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLYR 182 FAVLLGD I S P +QL+++ ER I VE VPR+ V RYGII+GE + +Y Sbjct: 122 AFAVLLGDTITSSGVPCTRQLMDIYERYGASAIAVEEVPRDKVERYGIIDGEEVSEGIYS 181 Query: 183 IKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNEIL 242 I+ +VEKP EAPSN+AI+GRY+L EIFD +RE PPG GEIQLTDA++ L E+ Sbjct: 182 IRDMVEKPPVTEAPSNLAIMGRYVLESEIFDHIREVPPGFGGEIQLTDAMRCL---EEVY 238 Query: 243 AKRIEGERYDIGSKFGFVMANLKLSLRREELRNEVLKYLKSIL 285 G YDIG++ ++ +L+ ++ +E+R E+++YLK+++ Sbjct: 239 GCVFRGRTYDIGNRVDWLKTSLEFAMNDDEIRPELIEYLKNLI 281 >gi|10956341 pXO1-94 [Bacillus anthracis] >gi|7474335|pir||F59102 probable UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) pXO1-94 [similarity] - Bacillus anthracis virulence plasmid pXO1 >gi|4894310|gb|AAD32398.1|AAD32398 (AF065404) pXO1-94 [Bacillus anthracis] Length = 295 Score = 312 bits (792), Expect = 2e-84 Identities = 150/288 (52%), Positives = 212/288 (73%), Gaps = 2/288 (0%) Query: 2 IRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRA 61 IRKA+IPAAGLGTR LP TK+ PKEMLPIVD+P I Y+VEEAV +GIEDI+I++G+GK Sbjct: 3 IRKAIIPAAGLGTRFLPATKAQPKEMLPIVDKPTIQYIVEEAVSSGIEDIIIVSGRGKHV 62 Query: 62 IEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNG 121 IED+FD+S+ELE L ++ K++ L ++E I + +I+Y+RQK+P GLG AI A + + Sbjct: 63 IEDHFDKSYELEQTLFKKNKIKTLEDIECISNLANIHYIRQKEPKGLGHAIYCARRFIGE 122 Query: 122 EPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIE--GELIEND 179 EPFAVLLGDDI+ S P +KQLI+V E + V+GV+ V VS+YGI++ + + Sbjct: 123 EPFAVLLGDDIVSSTYPCLKQLIDVYEEHHCSVVGVQRVLETEVSKYGIVKSANQNVNQS 182 Query: 180 LYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKN 239 + I LVEKP + APSN+AI+GRYIL P+IF++L+ P G GEIQLTDA+ +L + Sbjct: 183 IIPISMLVEKPPLETAPSNLAIMGRYILKPDIFEVLKNLPVGSGGEIQLTDAINVLNKQQ 242 Query: 240 EILAKRIEGERYDIGSKFGFVMANLKLSLRREELRNEVLKYLKSILKE 287 ++LA +G+RYD+G KFGF+ A + +L+RE L+ +VL YL++I ++ Sbjct: 243 KVLAFEFDGKRYDVGDKFGFIKATIDFALQRESLKEDVLSYLRNITRD 290 >sp|Q05852|GTAB_BACSU UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE (UDP-GLUCOSE PYROPHOSPHORYLASE) (UDPGP) (ALPHA-D-GLUCOSYL-1-PHOSPHATE URIDYLYLTRANSFERASE) (URIDINE DIPHOSPHOGLUCOSE PYROPHOSPHORYLASE) (GENERAL STRESS PROTEIN 33) (GSP33) >gi|538943|pir||A40650 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) gtaB [validated] - Bacillus subtilis >gi|289287|gb|AAA71967.1| (L12272) UDP-glucose pyrophosphorylase [Bacillus subtilis] >gi|405623|emb|CAA80241.1| (Z22516) UDP-glucose pyrophosphorylase [Bacillus subtilis] >gi|2636093|emb|CAB15584.1| (Z99122) UTP-glucose-1-phosphate uridylyltransferase [Bacillus subtilis] Length = 292 Score = 306 bits (776), Expect = 2e-82 Identities = 148/286 (51%), Positives = 205/286 (70%) Query: 2 IRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRA 61 +RKA+IPAAGLGTR LP TK+MPKEMLPIVD+P I Y++EEAV+AGIEDI+I+TGK KRA Sbjct: 4 VRKAIIPAAGLGTRFLPATKAMPKEMLPIVDKPTIQYIIEEAVEAGIEDIIIVTGKSKRA 63 Query: 62 IEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNG 121 IED+FD S ELE L+E+GK E L +V++ + DI+Y+RQK+P GLG A+ A + Sbjct: 64 IEDHFDYSPELERNLEEKGKTELLEKVKKASNLADIHYIRQKEPKGLGHAVWCARNFIGD 123 Query: 122 EPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLY 181 EPFAVLLGDDI+ ++ P ++QL++ E+ + +IGV+ VP E RYGII+ E Y Sbjct: 124 EPFAVLLGDDIVQAETPGLRQLMDEYEKTLSSIIGVQQVPEEETHRYGIIDPLTSEGRRY 183 Query: 182 RIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNEI 241 ++K VEKP APSN+AI+GRY+ PEIF L E G GEIQLTDA+Q L + Sbjct: 184 QVKNFVEKPPKGTAPSNLAILGRYVFTPEIFMYLEEQQVGAGGEIQLTDAIQKLNEIQRV 243 Query: 242 LAKRIEGERYDIGSKFGFVMANLKLSLRREELRNEVLKYLKSILKE 287 A EG+RYD+G K GF+ L+ +++ +ELR++++ +++ +L + Sbjct: 244 FAYDFEGKRYDVGEKLGFITTTLEFAMQDKELRDQLVPFMEGLLNK 289 >dbj|BAB07436.1| (AP001519) UTP-glucose-1-phosphate uridylyltransferase [Bacillus halodurans] Length = 293 Score = 303 bits (767), Expect = 2e-81 Identities = 152/286 (53%), Positives = 203/286 (70%), Gaps = 1/286 (0%) Query: 2 IRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRA 61 IRKA+IPAAGLGTR LP TK+MPKEMLPIVD+P I Y+VEEA+ +GIEDI+I+TGKGKRA Sbjct: 4 IRKAIIPAAGLGTRFLPATKAMPKEMLPIVDKPTIQYIVEEAISSGIEDIIIVTGKGKRA 63 Query: 62 IEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNG 121 IED+FD SFELE L E+ K + L +V E VDI+Y+RQK+P GLG A+ A K + Sbjct: 64 IEDHFDHSFELEQTLAEKEKYDLLEKVNE-STKVDIHYIRQKEPKGLGHAVWCARKFIGD 122 Query: 122 EPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLY 181 EPFAVLLGDDI+ ++ P +KQLI+ E+ + VIGV++V RYGI++ + Y Sbjct: 123 EPFAVLLGDDIVQAETPCLKQLIDQYEQTESSVIGVQTVADHETHRYGIVDPIDQKGRTY 182 Query: 182 RIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNEI 241 +K+ VEKP P APSN+AI+GRY+L PEIF L G GEIQLTDA++ L + Sbjct: 183 TVKQFVEKPKPGTAPSNLAIMGRYVLTPEIFTFLGRHETGAGGEIQLTDAIERLNEIQHV 242 Query: 242 LAKRIEGERYDIGSKFGFVMANLKLSLRREELRNEVLKYLKSILKE 287 A EG+RYD+G K GFV ++ +L E +++E ++L++IL++ Sbjct: 243 YAYDFEGKRYDVGEKIGFVKTTVEFALHDEAIKDEFARFLEAILEQ 288 >sp|Q58730|YD34_METJA PUTATIVE UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE (UDP-GLUCOSE PYROPHOSPHORYLASE) (UDPGP) (ALPHA-D-GLUCOSYL-1-PHOSPHATE URIDYLYLTRANSFERASE) (URIDINE DIPHOSPHOGLUCOSE PYROPHOSPHORYLASE) >gi|2129351|pir||E64466 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) MJ1334 [similarity] - Methanococcus jannaschii >gi|1591975|gb|AAB99341.1| (U67573) UDP-glucose pyrophosphorylase (gtaB) [Methanococcus jannaschii] Length = 283 Score = 294 bits (746), Expect = 6e-79 Identities = 145/285 (50%), Positives = 209/285 (72%), Gaps = 3/285 (1%) Query: 1 MIRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKR 60 MIRKAVIP AG GTR+LPITK+ PKEMLP+V++P++ YVVE+ V+AG++DIL +TGKGK+ Sbjct: 1 MIRKAVIPVAGFGTRLLPITKAQPKEMLPVVNKPIVQYVVEDLVEAGVKDILFVTGKGKQ 60 Query: 61 AIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVN 120 AIE++FD ++ELE L++ GK E L+ ++EI + +I+YVRQK+ GLGDAILY E+ V Sbjct: 61 AIENHFDVNYELECKLEKSGKYELLKIIKEIDRLGNIFYVRQKEQKGLGDAILYGEEFVG 120 Query: 121 GEPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDL 180 E F ++GD I K +K LI+ E+ VI +E VP+E V +YG+I+GE IE + Sbjct: 121 EEYFIAMVGDTIY--SKNIVKDLIKAHEKYGCSVIALERVPKEDVYKYGVIDGEEIEKGV 178 Query: 181 YRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNE 240 Y+IK +VEKP +EAPSN+ I G Y+L P+IF+ +RETPPGR GEIQ+TDA+ +LL + + Sbjct: 179 YKIKNMVEKPKVEEAPSNLIITGAYLLSPKIFEKIRETPPGRGGEIQITDAMNLLLKEED 238 Query: 241 ILAKRIEGERYDIGSKFGFVMANLKLSLRR-EELRNEVLKYLKSI 284 I+ I +RYDIG G++ AN+++ R E R + +++K++ Sbjct: 239 IIGVEINCKRYDIGDALGWLKANVEIGAERFPEFREFLKEFVKNL 283 >gb|AAG24457.1|AF312223_1 (AF312223) putative UTP-glucose-1-phosphate uridylyltransferase [Burkholderia pseudomallei] Length = 295 Score = 289 bits (732), Expect = 2e-77 Identities = 142/289 (49%), Positives = 203/289 (70%), Gaps = 1/289 (0%) Query: 2 IRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRA 61 + KAV P AGLGTR LP TK+ PKEMLP+VD+P+I Y V EA+ AGI +++ +TG+ KRA Sbjct: 4 VTKAVFPVAGLGTRFLPATKASPKEMLPVVDKPLIQYAVAEAINAGITEMIFVTGRSKRA 63 Query: 62 IEDYFDRSFELEYYLKERGKLEALREVEEIGEM-VDIYYVRQKKPLGLGDAILYAEKHVN 120 IED+FD+SFE+E L+ RGK + L V I VD +YVRQ LGLG A+L AEK V+ Sbjct: 64 IEDHFDKSFEIESELEARGKEKLLELVRGIKPSHVDCFYVRQPAALGLGHAVLCAEKLVH 123 Query: 121 GEPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDL 180 GEPFAV+L DD++ +P +KQL++V ++ VIGVE++ RE YGI+EG E D+ Sbjct: 124 GEPFAVILADDLLHGDQPVLKQLVDVFNHYHSSVIGVETIEREDSRSYGIVEGREWEEDI 183 Query: 181 YRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNE 240 ++ ++EKP+P+ APSN+ ++GRY+L+P IF+ L + G GE+QLTDA+Q LL + + Sbjct: 184 IKLSGIIEKPAPEHAPSNLGVVGRYVLMPSIFEHLLQIKRGAGGELQLTDAVQSLLTEEQ 243 Query: 241 ILAKRIEGERYDIGSKFGFVMANLKLSLRREELRNEVLKYLKSILKEIS 289 +LA R G R+D GSK G++ A ++L+LR E+ E YL++ L ++ Sbjct: 244 VLAYRYYGTRFDCGSKLGYLKATVELALRHPEVGREFEAYLRNCLPALA 292 >emb|CAA06172.1| (AJ004869) UTP-glucose-1-phosphate uridylyltransferase [Streptococcus pneumoniae] Length = 299 Score = 289 bits (732), Expect = 2e-77 Identities = 149/296 (50%), Positives = 208/296 (69%), Gaps = 8/296 (2%) Query: 2 IRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRA 61 +RKAVIPAAGLGTR LP TK++ KEMLPIVD+P I ++VEEA+K+GIEDIL++TGK KR+ Sbjct: 5 VRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEEALKSGIEDILVVTGKSKRS 64 Query: 62 IEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNG 121 IED+FD +FELEY LKE+GK + L+ V+E M ++++RQ P GLGDA+L A+ V Sbjct: 65 IEDHFDSNFELEYNLKEKGKTDLLKLVDETTGM-RLHFIRQTHPRGLGDAVLQAKAFVGN 123 Query: 122 EPFAVLLGDDI--IISKK--PAIKQLIEVAERKNTPVIGVESVPRELVSRYGII--EGEL 175 EPF V+LGDD+ I +K P KQL+ E+ + I V VP E VS YG+I +GE Sbjct: 124 EPFVVMLGDDLMDITDEKAVPLTKQLMNDYEKTHASTIAVMPVPHEDVSSYGVIAPQGE- 182 Query: 176 IENDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQIL 235 N LY ++ VEKP+P+E PS++AIIGRY+L PEIF+IL + PG EIQLTDA+ L Sbjct: 183 GSNGLYSVETFVEKPAPEETPSDLAIIGRYLLTPEIFEILEKQAPGAGNEIQLTDAIDTL 242 Query: 236 LNKNEILAKRIEGERYDIGSKFGFVMANLKLSLRREELRNEVLKYLKSILKEISNE 291 + A+ G RYD+G KFGF+ ++ +L+ ++++++ YL + KE++ + Sbjct: 243 NKTQRVFAREFTGTRYDVGDKFGFMKTSIDYALKHPQVKDDLKNYLIQLGKELTEK 298 >sp|Q54713|HASC_STRPY UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE (UDP-GLUCOSE PYROPHOSPHORYLASE) (UDPGP) (ALPHA-D-GLUCOSYL-1-PHOSPHATE URIDYLYLTRANSFERASE) (URIDINE DIPHOSPHOGLUCOSE PYROPHOSPHORYLASE) >gi|995767|gb|AAA91810.1| (U33452) UDP-glucose pyrophosphorylase [Streptococcus pyogenes] Length = 304 Score = 287 bits (727), Expect = 1e-76 Identities = 145/295 (49%), Positives = 207/295 (70%), Gaps = 12/295 (4%) Query: 2 IRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRA 61 +RKA+IPAAGLGTR LP TK++ KEMLPIVD+P I ++VEEA+K+GIE+IL++TGK KR+ Sbjct: 4 VRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEEALKSGIEEILVVTGKAKRS 63 Query: 62 IEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNG 121 IED+FD +FELEY L+ +GK E L+ V+E ++++++RQ P GLGDA+L A+ V Sbjct: 64 IEDHFDSNFELEYNLQAKGKNELLKLVDET-TAINLHFIRQSHPRGLGDAVLQAKAFVGN 122 Query: 122 EPFAVLLGDDII----ISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGII--EGEL 175 EPF V+LGDD++ S KP KQL+E ++ + I V VP E VS YG+I +G+ Sbjct: 123 EPFVVMLGDDLMDITNASAKPLTKQLMEDYDKTHASTIAVMKVPHEDVSSYGVIAPQGKA 182 Query: 176 IENDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQIL 235 ++ LY + VEKP P++APS++AIIGRY+L PEIFDIL PG E+QLTDA+ L Sbjct: 183 VKG-LYSVDTFVEKPQPEDAPSDLAIIGRYLLTPEIFDILERQTPGAGNEVQLTDAIDTL 241 Query: 236 LNKNEILAKRIEGERYDIGSKFGFVMANLKLSLR----REELRNEVLKYLKSILK 286 + A+ +G RYD+G KFGF+ ++ +L +E+L+N ++K K++ K Sbjct: 242 NKTQRVFAREFKGNRYDVGDKFGFMKTSIDYALEHPQVKEDLKNYIIKLGKALEK 296 >emb|CAB90754.1| (AJ400707) putative UDP-glucose pyrophosphorylase [Streptococcus uberis] Length = 304 Score = 284 bits (719), Expect = 8e-76 Identities = 140/293 (47%), Positives = 204/293 (68%), Gaps = 8/293 (2%) Query: 2 IRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRA 61 +RKA+IPAAGLGTR LP TK++ KEMLPIVD+P I ++VEEA+++GIE+IL++TGK KR+ Sbjct: 4 VRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEEALRSGIEEILVVTGKSKRS 63 Query: 62 IEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNG 121 IED+FD +FELEY L+E+GK E L+ V+E ++++++RQ P GLGDA+L A+ V Sbjct: 64 IEDHFDSNFELEYNLQEKGKTELLKLVDET-TSINLHFIRQSHPKGLGDAVLQAKAFVGN 122 Query: 122 EPFAVLLGDDII----ISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGII--EGEL 175 EPF V+LGDD++ P KQL++ E + I V VP + VS YG+I G+ Sbjct: 123 EPFIVMLGDDLMDITNTKAVPLTKQLMDDYETTHASTIAVMKVPHDDVSSYGVIAPNGKA 182 Query: 176 IENDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQIL 235 + N LY + VEKP P++APS++AIIGRY+L PEIFDIL PG E+QLTDA+ L Sbjct: 183 L-NGLYSVDTFVEKPKPEDAPSDLAIIGRYLLTPEIFDILENQAPGAGNEVQLTDAIDTL 241 Query: 236 LNKNEILAKRIEGERYDIGSKFGFVMANLKLSLRREELRNEVLKYLKSILKEI 288 + A+ G+RYD+G KFGF+ ++ +L+ ++++++ Y+ + KE+ Sbjct: 242 NKTQRVFAREFTGKRYDVGDKFGFMKTSIDYALKHHQVKDDLKAYIIKLGKEL 294 >dbj|BAA28714.1| (AB001562) glucose-1-phosphate uridylyltransferase [Streptococcus mutans] Length = 306 Score = 283 bits (716), Expect = 2e-75 Identities = 143/296 (48%), Positives = 205/296 (68%), Gaps = 8/296 (2%) Query: 2 IRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRA 61 +RKAVIPAAGLGTR LP TK++ KEMLPIVD+P I ++VEEA+K+GIEDIL++TGK KR+ Sbjct: 6 VRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEEALKSGIEDILVVTGKSKRS 65 Query: 62 IEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNG 121 IED+FD +FELEY L+++GK + L+ V + ++++++RQ P GLGDA+L A+ V Sbjct: 66 IEDHFDSNFELEYNLEQKGKTDLLKLVNDT-TAINLHFIRQSHPRGLGDAVLQAKAFVGN 124 Query: 122 EPFAVLLGDDI--IISKK--PAIKQLIEVAERKNTPVIGVESVPRELVSRYGII--EGEL 175 EPF V+LGDD+ I K P +QL+ E + I V VP E VS YG+I +GE Sbjct: 125 EPFVVMLGDDLMDITDDKAIPLTRQLMNDYEETHASTIAVMEVPHEDVSAYGVIAPQGEG 184 Query: 176 IENDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQIL 235 + + LY + VEKP+PKEAPSN+AIIGRY+L PEIF IL PG E+QLTDA+ L Sbjct: 185 V-SGLYSVDTFVEKPAPKEAPSNLAIIGRYLLTPEIFTILETQEPGAGNEVQLTDAIDTL 243 Query: 236 LNKNEILAKRIEGERYDIGSKFGFVMANLKLSLRREELRNEVLKYLKSILKEISNE 291 + A+ +G+RYD+G KFGF+ ++ +L+ +++ ++ Y+ + K++ + Sbjct: 244 NKTQRVFAREFKGKRYDVGDKFGFMKTSIDYALKHPQVKEDLKAYIIELGKKLDQK 299 >sp|Q54800|CAPC_STRPN UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE (UDP-GLUCOSE PYROPHOSPHORYLASE) (UDPGP) (ALPHA-D-GLUCOSYL-1-PHOSPHATE URIDYLYLTRANSFERASE) (URIDINE DIPHOSPHOGLUCOSE PYROPHOSPHORYLASE) >gi|695746|emb|CAA87405.1| (Z47210) glucosephosphate uridylyltransferase [Streptococcus pneumoniae] >gi|1586510|prf||2204223F UDP-glucose pyrophosphorylase [Streptococcus pneumoniae] Length = 306 Score = 282 bits (713), Expect = 4e-75 Identities = 141/292 (48%), Positives = 198/292 (67%), Gaps = 6/292 (2%) Query: 2 IRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRA 61 ++KAVIPAAGLGTR LP TK++ KEMLPIVDRP IH+V+EEA+++GIEDIL++TGK KR+ Sbjct: 4 VKKAVIPAAGLGTRFLPATKALAKEMLPIVDRPTIHFVIEEALRSGIEDILVVTGKSKRS 63 Query: 62 IEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNG 121 IEDYFD +FELEY L+++GK+E L+ V E + + +++VRQ P GLGDA+L A+ V Sbjct: 64 IEDYFDSTFELEYSLRKQGKMELLKSVNESTD-IKVHFVRQSSPRGLGDAVLQAKSFVGD 122 Query: 122 EPFAVLLGDDII----ISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGEL-I 176 +PF V+LGDD++ + P +QL++ I V V E VS YG+I L Sbjct: 123 DPFVVMLGDDLMDITDSTAVPLTRQLMDDYNATQASTIAVMPVRYEDVSSYGVISPRLES 182 Query: 177 ENDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILL 236 N LY + VEKP P+EAPSN+AIIGRY+L PEIF IL PG EIQLTDA+ L Sbjct: 183 SNGLYSVDAFVEKPKPEEAPSNLAIIGRYLLTPEIFSILETQKPGAGNEIQLTDAIDTLN 242 Query: 237 NKNEILAKRIEGERYDIGSKFGFVMANLKLSLRREELRNEVLKYLKSILKEI 288 + A+ G+RYD+G KF F+ ++ +L+ +++ + Y+ ++ K++ Sbjct: 243 KTQSVFAREFVGKRYDVGDKFNFMKTSIDYALQHPQIKESLKNYVIALGKQL 294 >pir||H70446 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) galF [similarity] - Aquifex aeolicus >gi|2984025|gb|AAC07568.1| (AE000752) UDP-glucose pyrophosphorylase [Aquifex aeolicus] Length = 297 Score = 280 bits (709), Expect = 1e-74 Identities = 133/286 (46%), Positives = 204/286 (70%) Query: 2 IRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRA 61 IRK V+P AG GTR LP TK+MPKEMLPI+D+P+I ++VE + GIE+I+ +TG+ K+A Sbjct: 4 IRKVVLPVAGWGTRFLPATKAMPKEMLPIIDKPIIQFIVESFINIGIENIIFVTGRHKKA 63 Query: 62 IEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNG 121 IED+FD + ELE +LK+ GK + LREV +I +++ YVRQK+ LGLG A+L AE V+ Sbjct: 64 IEDHFDHNHELEEHLKKAGKEKLLREVVKISSLINPIYVRQKEQLGLGHAVLMAEPAVSQ 123 Query: 122 EPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLY 181 EPF V LGD I+ +++ +K++I + + ++ + VP+E VS+YGI + + ++ + Y Sbjct: 124 EPFFVALGDIIVENEEEELKKMIHLFRKFGNSIVALMEVPKEEVSKYGIAKVKKLDEETY 183 Query: 182 RIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNEI 241 I LVEKPSP+EAPSN+AI+GRYI P IF+ L+ T PG+ GEIQLTDA+++LL + I Sbjct: 184 IIVDLVEKPSPEEAPSNLAIVGRYIFTPTIFEKLKVTKPGKGGEIQLTDAMRLLLEEEAI 243 Query: 242 LAKRIEGERYDIGSKFGFVMANLKLSLRREELRNEVLKYLKSILKE 287 A ++ YD G+ ++ + +LRRE++ E++++++ ++KE Sbjct: 244 YACKVNNTVYDTGNPKDYLKTVISFALRREDINGELIEFIRGLIKE 289 >gb|AAC43313.1| (U15171) glucose-1-phosphate uridylyltransferase [Streptococcus pneumoniae] >gi|1095718|prf||2109359C glucose-1-phosphate uridylyltransferase [Streptococcus pneumoniae] Length = 306 Score = 280 bits (708), Expect = 2e-74 Identities = 140/292 (47%), Positives = 198/292 (66%), Gaps = 6/292 (2%) Query: 2 IRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRA 61 ++KAVIPAAGLGTR LP TK++ KEMLPIVDRP IH+V+EEA+++GIEDIL++TGK KR+ Sbjct: 4 VKKAVIPAAGLGTRFLPATKALAKEMLPIVDRPTIHFVIEEALRSGIEDILVVTGKSKRS 63 Query: 62 IEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNG 121 IEDYFD +FELEY L+++GK+E L+ V E + + +++VRQ P GLGDA+L A+ V Sbjct: 64 IEDYFDSTFELEYSLRKQGKMELLKSVNESTD-IKVHFVRQSSPRGLGDAVLQAKSFVGD 122 Query: 122 EPFAVLLGDDII----ISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGEL-I 176 +PF V+LGDD++ + P +QL++ I V V E VS YG+I L Sbjct: 123 DPFVVMLGDDLMDITDSTAVPLTRQLMDDYNATQASTIAVMPVRYEDVSSYGVISPRLES 182 Query: 177 ENDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILL 236 N LY + VEKP P+EAPS++AIIGRY+L PEIF IL PG EIQLTDA+ L Sbjct: 183 SNGLYSVDAFVEKPKPEEAPSHLAIIGRYLLTPEIFSILETQKPGAGNEIQLTDAIDTLN 242 Query: 237 NKNEILAKRIEGERYDIGSKFGFVMANLKLSLRREELRNEVLKYLKSILKEI 288 + A+ G+RYD+G KF F+ ++ +L+ +++ + Y+ ++ K++ Sbjct: 243 KTQSVFAREFVGKRYDVGDKFNFMKTSIDYALQHPQIKESLKNYVIALGKQL 294 >sp|P47691|GALU_MYCGE UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE (UDP-GLUCOSE PYROPHOSPHORYLASE) (UDPGP) (ALPHA-D-GLUCOSYL-1-PHOSPHATE URIDYLYLTRANSFERASE) (URIDINE DIPHOSPHOGLUCOSE PYROPHOSPHORYLASE) >gi|1361891|pir||A64250 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) MG453 [similarity] - Mycoplasma genitalium >gi|3845047|gb|AAC72473.1| (U39727) UTP--glucose-1-phosphate uridylyltransferase (gtaB) [Mycoplasma genitalium] Length = 292 Score = 278 bits (703), Expect = 6e-74 Identities = 143/286 (50%), Positives = 192/286 (67%), Gaps = 3/286 (1%) Query: 2 IRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRA 61 IRKAVIPAAGLG R+LP TK++PKEMLP+V++P I Y+VEEAVK+GIE IL+I K A Sbjct: 5 IRKAVIPAAGLGVRLLPATKAIPKEMLPLVNKPTIQYIVEEAVKSGIEQILVIVSSKKTA 64 Query: 62 IEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNG 121 I D+FD LE L ++ KL+ +E+E+I + I++VRQK GLGDAIL+AE V Sbjct: 65 ILDHFDYDLILENALIQKNKLQEHKEIEDIANLAHIFFVRQKNQDGLGDAILFAESFVGN 124 Query: 122 EPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGII--EGELIEND 179 E FAVLLGDD++ SK+PA+KQ +E N IGV+ V V +YGII EG+ D Sbjct: 125 EDFAVLLGDDVVFSKEPALKQCLEAYYETNCQTIGVQEVDPCHVDKYGIITPEGDYKNKD 184 Query: 180 LYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKN 239 L ++ + EKP PK+A SN+AI+GRY+L P IF LR P G GE+QLTD L L Sbjct: 185 LIKVLAMTEKPKPKDAKSNLAILGRYVLKPSIFKALRSVPYGVGGELQLTDGLNFCLKNE 244 Query: 240 EILAKRIEGERYDIGSKFGFVMANLKLSLRREEL-RNEVLKYLKSI 284 A++ G R+D+G+K GF+ ANL +L +++ + EVL+ L + Sbjct: 245 NFYARKFTGTRFDVGTKSGFIKANLFTALNNKDISKKEVLELLNLV 290 >pir||E71913 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) galU [similarity] - Helicobacter pylori (strain J99) >gi|4155134|gb|AAD06164.1| (AE001491) UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE [Helicobacter pylori J99] Length = 273 Score = 272 bits (688), Expect = 4e-72 Identities = 134/265 (50%), Positives = 188/265 (70%), Gaps = 2/265 (0%) Query: 1 MIRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKR 60 MI+K + PAAG GTR LPITK++PKEMLPIVD+P+I Y VEEA++AG E + I+TG+ KR Sbjct: 1 MIKKCLFPAAGYGTRFLPITKTIPKEMLPIVDKPLIQYAVEEAMEAGCEVMAIVTGRNKR 60 Query: 61 AIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVN 120 ++EDYFD S+E+E+ ++ K AL+ + I E YVRQK+ GLG AIL E + Sbjct: 61 SLEDYFDTSYEIEHQIQGTNKENALKSIRNIIEKCCFSYVRQKQMKGLGHAILTGEALIG 120 Query: 121 GEPFAVLLGDDIIISKK--PAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIEN 178 EPFAV+L DD+ IS + +KQ+ + ++ ++ +E V E VS+YG+I GE +E Sbjct: 121 NEPFAVILADDLCISHEYPSVLKQMTSLYQKYQCSIVAIEEVVLEEVSKYGVIRGEWLEE 180 Query: 179 DLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNK 238 +Y IK +VEKPS ++APSN+A+IGRYIL P+IFDILRET PG++ EIQ+TDAL + Sbjct: 181 RVYEIKDMVEKPSQEDAPSNLAVIGRYILTPDIFDILRETKPGKNNEIQITDALLTQAKR 240 Query: 239 NEILAKRIEGERYDIGSKFGFVMAN 263 I+A + +G+RYD GS G++ A+ Sbjct: 241 KRIIAYQFKGKRYDCGSVEGYIEAS 265 >emb|CAB59678.1| (AL132674) UTP-glucose-1-phosphate uridylyltransferase [Streptomyces coelicolor A3(2)] Length = 303 Score = 271 bits (686), Expect = 6e-72 Identities = 142/291 (48%), Positives = 196/291 (66%), Gaps = 5/291 (1%) Query: 2 IRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRA 61 I KAVIPAAGLGTR LP TK+ PKEMLP+VD+P I YVVEEAV AG+ D+L++TG+ KR Sbjct: 8 ISKAVIPAAGLGTRFLPATKATPKEMLPVVDKPAIQYVVEEAVTAGLGDVLMVTGRNKRP 67 Query: 62 IEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNG 121 +ED+FDR++ELE L+++G L +V+E ++ ++YVRQ P GLG A+L A HV Sbjct: 68 LEDHFDRNYELESALQKKGDASRLAKVQESSDLAMMHYVRQGDPKGLGHAVLCAAPHVGH 127 Query: 122 EPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGE-LIENDL 180 EPFAVLLGDD+I + P ++++I+V E+ VI + V E + YG E ++D+ Sbjct: 128 EPFAVLLGDDLIDPRDPLLQRMIDVQEQYGGSVIALMEVAPEQIHLYGCAAVESTADSDV 187 Query: 181 YRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNE 240 ++ LVEKP P +APSN AIIGRY+L P +FDILR+T PGR GEIQLTDALQ L Sbjct: 188 VKVGGLVEKPDPADAPSNYAIIGRYVLDPHVFDILRKTEPGRGGEIQLTDALQQLAEDES 247 Query: 241 ----ILAKRIEGERYDIGSKFGFVMANLKLSLRREELRNEVLKYLKSILKE 287 + +G RYD G + ++ A ++L+ RE+L + +L+S + E Sbjct: 248 VGGPVHGVVFKGRRYDTGDRGDYLRAIVRLACEREDLGPDFRTWLRSYVAE 298 >pir||F64600 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) HP0646 [similarity] - Helicobacter pylori (strain 26695) >gi|2313766|gb|AAD07707.1| (AE000578) UDP-glucose pyrophosphorylase (galU) [Helicobacter pylori 26695] Length = 273 Score = 268 bits (678), Expect = 5e-71 Identities = 131/265 (49%), Positives = 187/265 (70%), Gaps = 2/265 (0%) Query: 1 MIRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKR 60 MI+K + PAAG GTR LPITK++PKEMLPIVD+P+I Y VEEA++AG E + I+TG+ KR Sbjct: 1 MIKKCLFPAAGYGTRFLPITKTIPKEMLPIVDKPLIQYAVEEAMEAGCEVMAIVTGRNKR 60 Query: 61 AIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVN 120 ++EDYFD S+E+E+ ++ K AL+ + I E YVRQK+ GLG AIL E + Sbjct: 61 SLEDYFDTSYEIEHQIQGTNKENALKSIRNIIEKCCFSYVRQKQMKGLGHAILTGEALIG 120 Query: 121 GEPFAVLLGDDIIIS--KKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIEN 178 EPFAV+L DD+ IS +KQ+ + ++ ++ +E V E VS+YG+I GE +E Sbjct: 121 NEPFAVILADDLCISHDHPSVLKQMTSLYQKYQCSIVAIEEVALEEVSKYGVIRGEWLEE 180 Query: 179 DLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNK 238 +Y IK +VEKP+ ++APSN+A+IGRYIL P+IF+IL ET PG++ EIQ+TDAL+ + Sbjct: 181 GVYEIKDMVEKPNQEDAPSNLAVIGRYILTPDIFEILSETKPGKNNEIQITDALRTQAKR 240 Query: 239 NEILAKRIEGERYDIGSKFGFVMAN 263 I+A + +G+RYD GS G++ A+ Sbjct: 241 KRIIAYQFKGKRYDCGSVEGYIEAS 265 >sp|P75124|GALU_MYCPN UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE (UDP-GLUCOSE PYROPHOSPHORYLASE) (UDPGP) (ALPHA-D-GLUCOSYL-1-PHOSPHATE URIDYLYLTRANSFERASE) (URIDINE DIPHOSPHOGLUCOSE PYROPHOSPHORYLASE) >gi|2146691|pir||S73501 probable UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) gtaB [similarity] - Mycoplasma pneumoniae (strain ATCC 29342) >gi|1673837|gb|AAB95823.1| (AE000018) UDP-glucose pyrophosphorylase [Mycoplasma pneumoniae] Length = 291 Score = 264 bits (668), Expect = 8e-70 Identities = 140/285 (49%), Positives = 196/285 (68%), Gaps = 4/285 (1%) Query: 2 IRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRA 61 IRKAVIPAAGLGTR+LP TK++PKEMLP+V++P I Y+VEEAV +GI++IL+I K A Sbjct: 4 IRKAVIPAAGLGTRLLPATKAIPKEMLPLVNKPTIQYIVEEAVASGIKEILVIVSSKKEA 63 Query: 62 IEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNG 121 I D+FD F LE L ++ K + +E+++I + IY+VRQK GLGDAIL+A+ V Sbjct: 64 IIDHFDYDFILENALLQKHKDQEHQEIKDIANLAHIYFVRQKHQHGLGDAILHAKSFVGN 123 Query: 122 EPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGII--EGELIEND 179 E FAVLLGDD++ ++PA+ Q I+ E+ + VIGV+ VP + V++YGI+ E + Sbjct: 124 EDFAVLLGDDVVFGEQPALAQCIQAYEQTDCQVIGVQEVPHDQVNKYGIVTPEANWQKQA 183 Query: 180 LYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKN 239 L +I +VEKP+ EA SN+AI+ RYIL P IF L++ P G GE+QLTD L L + Sbjct: 184 LVKILGMVEKPAVNEAKSNLAILSRYILKPSIFTALKQVPFGVGGELQLTDGLNYCLQQG 243 Query: 240 E-ILAKRIEGERYDIGSKFGFVMANLKLSLRREEL-RNEVLKYLK 282 E AK G R+D+G+K GF+ ANL +L+ + + ++EVL LK Sbjct: 244 EPFFAKHFGGTRFDVGTKNGFIKANLYTALKTDAITKDEVLAILK 288 >pir||D81930 probable UTP--glucose-1-phosphate uridylyltransferase NMA0848 [imported] - Neisseria meningitidis (group A strain Z2491) >gi|7379564|emb|CAB84129.1| (AL162754) putative UTP--glucose-1-phosphate uridylyltransferase [Neisseria meningitidis Z2491] Length = 289 Score = 262 bits (662), Expect = 4e-69 Identities = 134/272 (49%), Positives = 183/272 (67%), Gaps = 2/272 (0%) Query: 2 IRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRA 61 IRKAV P AG+GTR LP TK+ PKEMLPIVD+P+I Y VEEAV+AG +++ +TG+ KR+ Sbjct: 4 IRKAVFPVAGMGTRFLPATKASPKEMLPIVDKPLIQYAVEEAVEAGCTEMVFVTGRNKRS 63 Query: 62 IEDYFDRSFELEYYLKERGKLEALREVEEI-GEMVDIYYVRQKKPLGLGDAILYAEKHVN 120 IED+FD+++ELE L+ R K + L V I + Y+RQ + LGLG A+L A + Sbjct: 64 IEDHFDKAYELETELEMRHKDKLLEHVRNILPPNITCLYIRQAEALGLGHAVLCARAAIG 123 Query: 121 GEPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDL 180 EPFAV+L DD+I ++K A+KQ++EV ER ++GVE+V YGI+E E ++ Sbjct: 124 DEPFAVILADDLIDAQKGALKQMVEVYERSGNSILGVETVEPSQTGSYGIVETEQLK-QF 182 Query: 181 YRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNE 240 RI +VEKP P++APSN+A++GRYIL P IFD+L P G EIQLTD + LL+ Sbjct: 183 QRITGIVEKPKPEDAPSNLAVVGRYILTPRIFDLLTGLPRGAGNEIQLTDGIAKLLDHEF 242 Query: 241 ILAKRIEGERYDIGSKFGFVMANLKLSLRREE 272 +LA EG RYD GSK G++ A + L+ E Sbjct: 243 VLAHPFEGTRYDCGSKLGYLEATVAYGLKHPE 274 >pir||C81175 UTP--glucose-1-phosphate uridylyltransferase NMB0638 [imported] - Neisseria meningitidis (group B strain MD58) >gi|7225867|gb|AAF41061.1| (AE002419) UTP--glucose-1-phosphate uridylyltransferase [Neisseria meningitidis MC58] Length = 289 Score = 259 bits (656), Expect = 2e-68 Identities = 133/272 (48%), Positives = 181/272 (65%), Gaps = 2/272 (0%) Query: 2 IRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRA 61 IRKAV P AG+GTR LP TK+ PKEMLPIVD+P+I Y VEEAV+AG +++ +TG+ KR+ Sbjct: 4 IRKAVFPVAGMGTRFLPATKASPKEMLPIVDKPLIQYAVEEAVEAGCTEMVFVTGRNKRS 63 Query: 62 IEDYFDRSFELEYYLKERGKLEALREVEEI-GEMVDIYYVRQKKPLGLGDAILYAEKHVN 120 IED+FD+++ELE L+ R K + L V I + Y+RQ + LGLG A+L A + Sbjct: 64 IEDHFDKAYELETELEMRHKDKLLEHVRNILPPNITCLYIRQAEALGLGHAVLCARAAIG 123 Query: 121 GEPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDL 180 EPFAV+L DD+I + K A+KQ++EV R ++GVE+V YGI+E E ++ Sbjct: 124 DEPFAVILADDLIDAPKGALKQMVEVYGRSGNSILGVETVEASQTGSYGIVETEQLK-QF 182 Query: 181 YRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNE 240 RI +VEKP P++APSN+A++GRYIL P IFD+L P G EIQLTD + LL+ Sbjct: 183 QRITGIVEKPKPEDAPSNLAVVGRYILTPRIFDLLTNLPRGAGNEIQLTDGIAKLLDHEF 242 Query: 241 ILAKRIEGERYDIGSKFGFVMANLKLSLRREE 272 +LA EG RYD GSK G++ A + L+ E Sbjct: 243 VLAHPFEGTRYDCGSKLGYLEATVAYGLKHPE 274 >pir||A83394 UTP--glucose-1-phosphate uridylyltransferase PA2023 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9948027|gb|AAG05411.1|AE004628_9 (AE004628) UTP--glucose-1-phosphate uridylyltransferase [Pseudomonas aeruginosa] Length = 279 Score = 255 bits (644), Expect = 5e-67 Identities = 120/264 (45%), Positives = 185/264 (69%), Gaps = 2/264 (0%) Query: 1 MIRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKR 60 MI+K + PAAG GTR LP TK+MPKEMLP+V++P+I Y VEEA++AG+ +I I+TG+GKR Sbjct: 1 MIKKCLFPAAGYGTRFLPATKAMPKEMLPVVNKPLIQYAVEEALEAGLSEIGIVTGRGKR 60 Query: 61 AIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVN 120 ++ED+FD S+ELE+ ++ K + L + + + Y RQ + GLG AIL + Sbjct: 61 SLEDHFDISYELEHQIRNTDKEKYLVGIRRLIDECTFAYTRQVEMKGLGHAILTGRPLIG 120 Query: 121 GEPFAVLLGDDIIISKK--PAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIEN 178 EPFAV+L DD+ ++ + +KQ++++ + ++ ++ VP E ++YG+I GE+I + Sbjct: 121 DEPFAVVLADDLCLNLEGDSVLKQMVKLYNQFRCSIVAIQEVPPEETNKYGVIAGEMIRD 180 Query: 179 DLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNK 238 D++R+ +VEKP P+EAPSN+AIIGRYIL P+IFD++ +T PG+ GEIQ+TDAL Sbjct: 181 DIFRVNTMVEKPKPEEAPSNLAIIGRYILTPDIFDLIEQTEPGKGGEIQITDALMKQAQD 240 Query: 239 NEILAKRIEGERYDIGSKFGFVMA 262 +LA + +G+R+D GS G++ A Sbjct: 241 GCVLAYKFKGKRFDCGSAEGYIEA 264 >pir||H82325 UTP--glucose-1-phosphate uridylyltransferase VC0395 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9654816|gb|AAF93568.1| (AE004128) UTP--glucose-1-phosphate uridylyltransferase [Vibrio cholerae] Length = 291 Score = 253 bits (640), Expect = 2e-66 Identities = 119/263 (45%), Positives = 186/263 (70%), Gaps = 1/263 (0%) Query: 1 MIRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKR 60 MI+K + PAAG GTR LP TKSMPKEM+P+V++P+I Y V+EA++AGI + I+TG+GK Sbjct: 2 MIKKCLFPAAGYGTRFLPATKSMPKEMMPVVNKPLIEYGVDEAIQAGITGMCIVTGRGKH 61 Query: 61 AIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVN 120 +I D+FD ++ELE+ ++ K E L ++ +I E + ++RQ++ GLG AIL ++ V Sbjct: 62 SIMDHFDMNYELEHQIRGTNKEELLGDIRKIIESANFTFIRQREMKGLGHAILTGKELVG 121 Query: 121 GEPFAVLLGDDIIISKKPAI-KQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIEND 179 EPFAV+L DD+ ++++ + Q++ + ++ ++ V+ VP +YG+I GE+I++D Sbjct: 122 DEPFAVVLADDLCVNEEQGVLAQMVALYKQFRCSIVAVQEVPENETHKYGVIAGEMIKDD 181 Query: 180 LYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKN 239 L+R+ +VEKP P APSN+AIIGRYIL P+IFD++ +T PG+ GEIQ+TDAL Sbjct: 182 LFRVDNMVEKPEPGTAPSNLAIIGRYILTPDIFDLIEQTEPGKGGEIQITDALLKQAKAG 241 Query: 240 EILAKRIEGERYDIGSKFGFVMA 262 +LA + +G+R+D GS G++ A Sbjct: 242 CVLAYKFKGKRFDCGSVEGYIEA 264 >pir||F81300 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) Cj1536c [imported] - Campylobacter jejuni (strain NCTC 11168) >gi|6968955|emb|CAB73952.1| (AL139078) UTP--glucose-1-phosphate uridylyltransferase [Campylobacter jejuni] Length = 274 Score = 248 bits (626), Expect = 7e-65 Identities = 122/264 (46%), Positives = 176/264 (66%), Gaps = 2/264 (0%) Query: 1 MIRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKR 60 M++ + PAAG GTR LP TK++PKEMLPI+ +P+IHY V+EA++AG+E++ +TG+GKR Sbjct: 1 MLQTCIFPAAGYGTRFLPATKTLPKEMLPILTKPLIHYGVDEALEAGMENMGFVTGRGKR 60 Query: 61 AIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVN 120 A+EDYFD S+ELE+ + K L E+ + + RQ + GLGDA+L V Sbjct: 61 ALEDYFDISYELEHQISGTKKEYLLDEIRSLINRCTFTFTRQNQMKGLGDAVLKGRPLVG 120 Query: 121 GEPFAVLLGDDIIISKK--PAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIEN 178 E F V+L DD+ ++++ + Q++++ E+ +I V VP+E VS YG+I G +E Sbjct: 121 DEAFGVILADDLCVNEEGLNVMAQMVKIYEKYRCTIIAVMEVPKEQVSNYGVISGNFVEE 180 Query: 179 DLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNK 238 +L + ++EKPSP EAPSN+AIIGRYIL P+IF IL T G++GEIQLTDAL Sbjct: 181 NLIMVNSMIEKPSPDEAPSNLAIIGRYILTPDIFGILENTKAGKNGEIQLTDALLTQATN 240 Query: 239 NEILAKRIEGERYDIGSKFGFVMA 262 +LA + +G+R+D GS GFV A Sbjct: 241 GMVLAYKFQGKRFDCGSVEGFVEA 264 >pir||JC4985 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) [validated] - Xanthomonas campestris >gi|1628575|gb|AAB17376.1| (U65532) UDP-glucose pyrophosphorylase [Xanthomonas campestris] Length = 324 Score = 247 bits (624), Expect = 1e-64 Identities = 129/286 (45%), Positives = 185/286 (64%), Gaps = 2/286 (0%) Query: 2 IRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRA 61 IRKAV P AGLGTR LP TK++PKEMLPI+D+P+I Y V+EA++AG + ++ +T + K + Sbjct: 5 IRKAVFPVAGLGTRFLPATKTVPKEMLPIIDKPLIQYAVDEAIQAGCDTLIFVTNRYKHS 64 Query: 62 IEDYFDRSFELEYYLKERGKLEALREVEE-IGEMVDIYYVRQKKPLGLGDAILYAEKHVN 120 I DYFD+++ELE L+ GKLE L V + E V +V Q + LGLG A+L A+ V Sbjct: 65 IADYFDKAYELEQKLERAGKLEQLELVRHALPEGVRAIFVTQAEALGLGHAVLCAKAVVG 124 Query: 121 GEPFAVLLGDDIIISK-KPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIEND 179 EPFAVLL DD++ ++ A+ Q+ +VAE VI VE VP + + YGI+ + + Sbjct: 125 DEPFAVLLPDDLMWNRGDAALTQMADVAEASGGSVIAVEDVPHDKTASYGIVSTDAFDGR 184 Query: 180 LYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKN 239 RI +VEKP P+ APSN+A++GRY+L P+IF+ L T G GEIQLTDA+ LL + Sbjct: 185 KGRINAIVEKPKPEVAPSNLAVVGRYVLSPKIFEYLESTGAGAGGEIQLTDAIAELLKQE 244 Query: 240 EILAKRIEGERYDIGSKFGFVMANLKLSLRREELRNEVLKYLKSIL 285 ++ A R EG R+D G+ G + A + +L E+ + ++S L Sbjct: 245 QVDAFRFEGRRFDCGAHIGLIEATVHFALEHEKHGAPAKEIIRSAL 290 >pir||D82558 UTP-glucose-1-phosphate uridylyltransferase XF2432 [imported] - Xylella fastidiosa (strain 9a5c) >gi|9107623|gb|AAF85231.1|AE004052_6 (AE004052) UTP-glucose-1-phosphate uridylyltransferase [Xylella fastidiosa] Length = 296 Score = 245 bits (619), Expect = 4e-64 Identities = 129/286 (45%), Positives = 185/286 (64%), Gaps = 2/286 (0%) Query: 2 IRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRA 61 IRKAV P AGLGTR LP TK++PKEMLPI+D+P+I Y V+EA++AG + ++ +T + K A Sbjct: 5 IRKAVFPVAGLGTRFLPATKTIPKEMLPIIDKPLIQYAVDEAIQAGCDTLVFVTNRYKHA 64 Query: 62 IEDYFDRSFELEYYLKERGKLEALREVEEI-GEMVDIYYVRQKKPLGLGDAILYAEKHVN 120 + DYFD+++ELE L+ GK E L V + + V +V Q + LGLG A+L A+ V Sbjct: 65 VADYFDKAYELEQKLERAGKYEQLELVRHVLPDGVRTVFVTQTEALGLGHAVLCAKPVVG 124 Query: 121 GEPFAVLLGDDIIISKKP-AIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIEND 179 EPFAVLL DD++ S+ A+KQ+ +VAE + VI VE VP + YGI+ ++ + Sbjct: 125 DEPFAVLLPDDLMWSRNGGALKQMADVAEVSGSSVIAVEDVPVDKTVNYGIVGTDVFDGS 184 Query: 180 LYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKN 239 RI ++VEKP P +APSN+A++GRY+L +IF++L T G GEIQLTDA+ LL Sbjct: 185 KGRITQIVEKPKPDDAPSNLAVVGRYVLSGKIFEMLENTSIGTGGEIQLTDAIAELLKYE 244 Query: 240 EILAKRIEGERYDIGSKFGFVMANLKLSLRREELRNEVLKYLKSIL 285 + A R +G R+D G+ G + A L L+L + V + L+ L Sbjct: 245 RVDAYRFQGRRFDCGAHIGLIEATLHLALEHRKHGQAVREILRDTL 290 >gb|AAF61451.1|AF139598_1 (AF139598) UDPG-pyrophosphorylase [Acetobacter xylinus] Length = 289 Score = 243 bits (615), Expect = 1e-63 Identities = 127/285 (44%), Positives = 183/285 (63%), Gaps = 7/285 (2%) Query: 2 IRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRA 61 ++KAV+P AGLGTR LP TK +PKEML +VDRP+I Y ++EA +AGIE+ +++ +GK + Sbjct: 5 LKKAVLPVAGLGTRFLPATKCVPKEMLTVVDRPLIQYAIDEAREAGIEEFCLVSSRGKDS 64 Query: 62 IEDYFDRSFELEYYLKERGKLEALREVEEI----GEMVDIYYVRQKKPLGLGDAILYAEK 117 + DYFD S+ELE LK R K AL+ +E G M+ VRQ++PLGLG AI A + Sbjct: 65 LIDYFDISYELEDTLKARKKTSALKALEATRVTPGSMLS---VRQQEPLGLGHAIWCARE 121 Query: 118 HVNGEPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIE 177 + +PFA+LL DD++ S+K I QL+EV + V+ V VPRE YGI++ + Sbjct: 122 FIGNDPFAILLPDDVVQSEKSCIGQLVEVYNKTGGNVLAVTEVPREQTGSYGILDVGADD 181 Query: 178 NDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLN 237 +K LVEKP PK+APS +++IGRY+L ++ L + G GE+QLTDA+ + Sbjct: 182 GKTVEVKGLVEKPDPKDAPSTLSVIGRYVLTADVLKHLAKLEKGAGGEVQLTDAMAKTIG 241 Query: 238 KNEILAKRIEGERYDIGSKFGFVMANLKLSLRREELRNEVLKYLK 282 R EG+R+D GSK GF+ A + +L RE+L +V ++LK Sbjct: 242 HVPFHGYRYEGKRFDCGSKPGFLEAQIAFALAREDLAGDVREFLK 286 >dbj|BAB06022.1| (AP001515) UTP-glucose-1-phosphate uridylyltransferas [Bacillus halodurans] Length = 273 Score = 238 bits (601), Expect = 6e-62 Identities = 128/255 (50%), Positives = 170/255 (66%), Gaps = 5/255 (1%) Query: 2 IRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRA 61 I+KA+IPAAG GTR LPITK +PKEM PI + +HY+VEEAV AGIE+I II + + Sbjct: 3 IKKAIIPAAGYGTRCLPITKVVPKEMFPINGKAALHYIVEEAVAAGIEEIFIILSRNRTL 62 Query: 62 IEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNG 121 I DYFDRS ELE +LK+ K L ++ V I ++RQ GLGDAI E+ VNG Sbjct: 63 IMDYFDRSIELETFLKKMNKQHLLEKLAL--PDVTIQFIRQPHANGLGDAIRLGERFVNG 120 Query: 122 EPFAVLLGDDIIISKK--PAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIEND 179 EPFAVLL DD+ IS K + +L+ V ++ N +IG++ V EL+ RYG+I G + +D Sbjct: 121 EPFAVLLPDDLFISPKHTSVLAELVNVYKQYNKSIIGLQEVESELLKRYGVIAGHPLSSD 180 Query: 180 LYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKN 239 Y+I+ +VEKP PSN+AI+GRYI P IF L+ G+ GE+QLTDA++ LL + Sbjct: 181 EYKIENVVEKPQ-TNPPSNLAIVGRYIFEPAIFQKLKNIGIGKGGEVQLTDAIKALLISH 239 Query: 240 EILAKRIEGERYDIG 254 ++ K IEG RYDIG Sbjct: 240 TVIGKIIEGCRYDIG 254 >emb|CAA09328.1| (AJ010734) UDP-glucose pyrophosphorylase [Pseudomonas aeruginosa] Length = 278 Score = 237 bits (598), Expect = 1e-61 Identities = 114/264 (43%), Positives = 183/264 (69%), Gaps = 3/264 (1%) Query: 1 MIRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKR 60 MI+K + PAAG GTR LP TK+MPKEMLP+V++P+I Y VEEA++AG+ +I I+TG+GK Sbjct: 1 MIKKCLFPAAGYGTRFLPATKAMPKEMLPVVNKPLIQYAVEEALEAGLSEIGIVTGRGKP 60 Query: 61 AIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVN 120 ++ED+FD S+ELE+ ++ K + L + + + Y RQ + GLG AIL + + Sbjct: 61 SLEDHFDISYELEHQIRNTDKEKYLVGIRRLIDECTFAYTRQVEMKGLGHAILTG-RPLM 119 Query: 121 GEPFAVLLGDDIIISKKPA--IKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIEN 178 F+V+L DD+ ++ + A +KQ++++ + ++ ++ VP E ++YG+I E+I + Sbjct: 120 AATFSVVLADDLCLNLEGAQVLKQMVKLYNQWRCSIVAIQEVPPEETNKYGVIAAEMIRD 179 Query: 179 DLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNK 238 D++R+ +VEKP P+EAPSN+AIIGRYIL P+IFD++ +T PG+ GEI++TDAL Sbjct: 180 DIFRVNTMVEKPKPEEAPSNLAIIGRYILTPDIFDLIEQTEPGKGGEIRVTDALMKQAQD 239 Query: 239 NEILAKRIEGERYDIGSKFGFVMA 262 +LA + +G+R+D G+ G++ A Sbjct: 240 GCVLAYKFKGKRFDCGTAEGYIEA 263 >gb|AAD19415.1| (AF102543) UTP-glucose-1-phosphate uridyltransferase; UDPGP [Zymomonas mobilis] Length = 292 Score = 236 bits (596), Expect = 2e-61 Identities = 128/276 (46%), Positives = 182/276 (65%), Gaps = 8/276 (2%) Query: 2 IRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRA 61 +RKA+ P AG GTR LP TK+MPKEMLP+VDRP+I Y V+EA AGIE+++ +TG+GK+A Sbjct: 4 VRKAIFPVAGQGTRFLPATKAMPKEMLPVVDRPLIQYAVDEARAAGIEELIFVTGRGKQA 63 Query: 62 IEDYFDRSFELEYYLKERGKLEALREVEEIGEMV---DIYYVRQKKPLGLGDAILYAEKH 118 IEDYFD ++ELE L +GK L +E G V ++RQ++PLGLG A+ A Sbjct: 64 IEDYFDIAYELEASLTAKGKTGMLDLLE--GTRVAPGRACFIRQQEPLGLGHAVWCARDL 121 Query: 119 VNGEPFAVLLGDDIIIS-KKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIE 177 + EPFAVLL D+++ + K+P++ QL+E +K V+ V VP E RYGI++ + Sbjct: 122 IGDEPFAVLLPDELLWNPKRPSLVQLVETYNQKGGNVVTVMEVPEEHTHRYGIVDPGKTD 181 Query: 178 NDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLN 237 ++ +K LVEK P++APS +A+ GRYIL P+I +L + G GEIQLTD++ L+ Sbjct: 182 GEVTEVKGLVEK--PEKAPSRLAMTGRYILQPDIMPLLAQDNRGVGGEIQLTDSMAQLIG 239 Query: 238 KNEILAKRIEGERYDIGSKFGFVMANLKLSLRREEL 273 K A R G R+D G K GF+ AN+ L+L R ++ Sbjct: 240 KQPFHACRFGGIRHDCGDKAGFIQANVALALERPDI 275 >sp|Q59633|GALU_PSEAE UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE (UDP-GLUCOSE PYROPHOSPHORYLASE) (UDPGP) (ALPHA-D-GLUCOSYL-1-PHOSPHATE URIDYLYLTRANSFERASE) (URIDINE DIPHOSPHOGLUCOSE PYROPHOSPHORYLASE) >gi|1345068|gb|AAB01486.1| (U03751) UDP-glucose pyrophosphorylase [Pseudomonas aeruginosa] Length = 279 Score = 234 bits (590), Expect = 1e-60 Identities = 116/264 (43%), Positives = 178/264 (66%), Gaps = 2/264 (0%) Query: 1 MIRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKR 60 MI+K + PAAG GTR LP TK+MPKEMLP+V++P+I Y VEEA+ AG+ +I I+TG+GKR Sbjct: 1 MIKKYLFPAAGYGTRFLPATKAMPKEMLPVVNKPLIQYGVEEALDAGLNEISIVTGRGKR 60 Query: 61 AIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVN 120 A+ED+FD S+ELE +K K + L + ++ + Y RQ + GLG AIL + Sbjct: 61 ALEDHFDISYELENQIKGTDKEKYLVGIRKLLDECSFSYTRQTQMKGLGHAILTGRPLIG 120 Query: 121 GEPFAVLLGDDIIISKK--PAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIEN 178 EPFAV+L DD+ ++ + + Q++++ ++ ++ V V ++YG+I G+ I + Sbjct: 121 DEPFAVVLADDLCVNLEGDGVLTQMVKLYQKYRCTIVAVMEVNPTETNKYGVIAGDDIGD 180 Query: 179 DLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNK 238 L R++ +VEKP+P++APSN+AIIGRYIL P+IF ++ ET PG+ GEIQ+TDAL Sbjct: 181 GLIRVRDMVEKPAPEDAPSNLAIIGRYILTPDIFKLIEETEPGKGGEIQITDALLKQAKD 240 Query: 239 NEILAKRIEGERYDIGSKFGFVMA 262 ++A + +G+R+D G G++ A Sbjct: 241 GCVIAYKFKGQRFDCGGAEGYIEA 264 >pir||T44841 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) galU [similarity] - Acinetobacter lwoffii >gi|6010002|emb|CAB57209.1| (AJ243431) putative UTP-glucose-1-phosphate uridylyltransferase [Acinetobacter lwoffii] Length = 291 Score = 233 bits (588), Expect = 2e-60 Identities = 129/295 (43%), Positives = 191/295 (64%), Gaps = 11/295 (3%) Query: 1 MIRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKR 60 MI+KA++P AGLGTR LP +KS+PKEM+ +VDRP I YVV EAV+AGIE I+++T K Sbjct: 1 MIKKAILPVAGLGTRFLPASKSIPKEMVTVVDRPAIEYVVREAVEAGIEQIILVTHSSKA 60 Query: 61 AIEDYFDRSFELEYYLKERGKLEALREVEEI-GEMVDIYYVRQKKPLGLGDAILYAEKHV 119 +IE+YFDR+FELE L+++ K + L+E+ +I + V + VRQ +PLGLG A+L A+ + Sbjct: 61 SIENYFDRNFELETILEQKKKFDLLKEITDILPKHVSVISVRQPQPLGLGHAVLCAKDVI 120 Query: 120 NGEPFAVLLGDDIIISKKPA---IKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELI 176 E FAVLL D+++ A + ++I E+ N I VE+VP LV +YGI++ E Sbjct: 121 GNEAFAVLL-PDVLVKDAEADNDLSRMIRRFEQSNAAQIMVEAVPDHLVDQYGIVDVENS 179 Query: 177 ENDLYRI--KRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQI 234 N+ I + +VEKPS APSN++++GRYIL +I +L TP G EIQLTDA+ Sbjct: 180 PNEGESIVMQGIVEKPSVGTAPSNLSVVGRYILPAQIMALLENTPRGAGNEIQLTDAIAA 239 Query: 235 LLNKNEILAKRIEGERYDIGSKFGFVMANLKLSLRREELRNEVLKYLKSILKEIS 289 L + A R++G+ +D GSK G++ A L + +L E K +++E++ Sbjct: 240 LQQSETVEAYRMKGQTFDCGSKIGYLKAVLHYGIEHPKLGEE----FKGLIRELA 290 >sp|P42407|YTDA_BACSU PUTATIVE UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE (UDP-GLUCOSE PYROPHOSPHORYLASE) (UDPGP) (ALPHA-D-GLUCOSYL-1-PHOSPHATE URIDYLYLTRANSFERASE) (URIDINE DIPHOSPHOGLUCOSE PYROPHOSPHORYLASE) >gi|7434853|pir||A69990 UTP--glucose-1-phosphate uridylyltransferase homolog ytdA [imported] - Bacillus subtilis >gi|669000|gb|AAA62287.1| (U20447) ORFX, similar to Bacillus subtilis UDP-glucose pyrophosphorylase (GtaB), Swiss-Prot Accession Q05852 >gi|2293144|gb|AAC00222.1| (AF008220) YtdA [Bacillus subtilis] >gi|2635569|emb|CAB15063.1| (Z99119) alternate gene name: yzwA~similar to UTP-glucose-1-phosphate uridylyltransferase [Bacillus subtilis] Length = 272 Score = 229 bits (577), Expect = 4e-59 Identities = 123/255 (48%), Positives = 166/255 (64%), Gaps = 4/255 (1%) Query: 1 MIRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKR 60 MI+KA+IPA G GTR LP+TK +PKEM P+ +PVIHY+VEE ++GIEDIL++ K Sbjct: 1 MIKKAIIPAGGFGTRNLPVTKVIPKEMFPVGSKPVIHYLVEELKESGIEDILMVVSSHKN 60 Query: 61 AIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVN 120 I DYFD S LE +L + KL LRE I + + I+YVRQ GLGDAI + ++ Sbjct: 61 LIVDYFDSSLALEAFLASKNKLHLLRE-HPIPD-IRIHYVRQPYAKGLGDAISFGKQFAG 118 Query: 121 GEPFAVLLGDDIIIS-KKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIEND 179 GEPFAV+L DD+I S +PA+ QLIE + + VIG++ E + YG+I+GE +E Sbjct: 119 GEPFAVVLPDDLIFSANQPALGQLIEAYTKYQSSVIGLKETKTEDLHHYGVIKGEPVEKG 178 Query: 180 LYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKN 239 LYRI+ +VEKP + PS+ A GRYI P+IF+ L GE+Q+TDA++ L Sbjct: 179 LYRIQDIVEKPK-QNPPSHFAAAGRYIFTPDIFNELEALEADSGGEVQVTDAIKASLGAC 237 Query: 240 EILAKRIEGERYDIG 254 + K +EGERYDIG Sbjct: 238 TVYGKLLEGERYDIG 252 >sp|P44878|GALU_HAEIN UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE (UDP-GLUCOSE PYROPHOSPHORYLASE) (UDPGP) (ALPHA-D-GLUCOSYL-1-PHOSPHATE URIDYLYLTRANSFERASE) (URIDINE DIPHOSPHOGLUCOSE PYROPHOSPHORYLASE) >gi|1074135|pir||G64095 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) HI0812 [similarity] - Haemophilus influenzae (strain Rd KW20) >gi|1573824|gb|AAC22471.1| (U32763) glucosephosphate uridylyltransferase (galU) [Haemophilus influenzae Rd] Length = 295 Score = 225 bits (568), Expect = 4e-58 Identities = 127/294 (43%), Positives = 183/294 (62%), Gaps = 9/294 (3%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 KAVIP AGLGTRMLP TK++PKEML +VD+P+I YVV E V AGI++I+++T K AIE Sbjct: 2 KAVIPVAGLGTRMLPATKAIPKEMLTLVDKPLIQYVVNECVAAGIKEIVLVTHSSKNAIE 61 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEI-GEMVDIYYVRQKKPLGLGDAILYAEKHVNGE 122 ++FD SFELE L++R K + L EV I + V I +VRQ GLG A+L V E Sbjct: 62 NHFDTSFELETMLEKRVKRQLLEEVRSICPKNVTIMHVRQGNAKGLGHAVLCGRPLVGNE 121 Query: 123 PFAVLLGDDIII-----SKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEG---E 174 FAV+L D ++ KK + +I+ I V VP+E VS YG+ + E Sbjct: 122 SFAVMLPDVLLAEFSADQKKENLAAMIQRFNETGASQIMVTPVPQENVSSYGVADCGGIE 181 Query: 175 LIENDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQI 234 L + +I +VEKPS ++APSN+A++GRY+ I+D+L +TP G EIQLTDA+ + Sbjct: 182 LNGGESAKINSIVEKPSIEDAPSNLAVVGRYVFSAAIWDLLEKTPIGVGDEIQLTDAIDM 241 Query: 235 LLNKNEILAKRIEGERYDIGSKFGFVMANLKLSLRREELRNEVLKYLKSILKEI 288 L+ K + A + GE +D G K G++ A ++ +R E+L E ++K++ K + Sbjct: 242 LIEKETVEAFHMTGETFDCGDKIGYMEAFVEYGIRHEKLGKEFKSFIKNLAKTL 295 >gb|AAC28326.1| (AF053017) UTP-glucose-1-phosphate uridylyltransferase [Actinobacillus pleuropneumoniae] Length = 295 Score = 222 bits (560), Expect = 4e-57 Identities = 123/294 (41%), Positives = 182/294 (61%), Gaps = 9/294 (3%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 K +IP AGLGTRMLP TK++PKEML I D+P+I Y+V E V AGI++I+++T K AIE Sbjct: 2 KVIIPVAGLGTRMLPATKAIPKEMLTIADKPLIQYIVNECVAAGIKEIVLVTHSSKNAIE 61 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEI-GEMVDIYYVRQKKPLGLGDAILYAEKHVNGE 122 ++FD SFELE L++R K + L EV I + V + +VRQ + GLG A+L V E Sbjct: 62 NHFDTSFELETMLEKRVKRQLLEEVRSIVPKDVTLMHVRQGQAKGLGHAVLCGRAVVGNE 121 Query: 123 PFAVLLGDDIII-----SKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIE 177 PFAV+L D I+ K + +I+ I V VPRE VS YG+ + + +E Sbjct: 122 PFAVVLPDVILADFTANQKTENLAAMIKRFNETQHSQIMVAPVPREDVSSYGVADCDGVE 181 Query: 178 ---NDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQI 234 + +I ++VEKPS +EAPSN+A++GRY+ I+D+L +TP G EIQLTDA+ + Sbjct: 182 IPAGETAKIVKMVEKPSVEEAPSNLAVVGRYVFSAGIWDLLEKTPVGVGDEIQLTDAIDM 241 Query: 235 LLNKNEILAKRIEGERYDIGSKFGFVMANLKLSLRREELRNEVLKYLKSILKEI 288 L+ + + A + G +D G K G++ A + SLR ++ N +++K + K + Sbjct: 242 LIEQETVEAFHMTGRTFDCGDKLGYMQAFTEYSLRHDKFGNNFKEFIKKLAKTL 295 >gb|AAG23691.1|AF297520_3 (AF297520) UDP-glucose pyrophosphorylase [Haemophilus ducreyi] Length = 295 Score = 219 bits (551), Expect = 4e-56 Identities = 125/294 (42%), Positives = 180/294 (60%), Gaps = 9/294 (3%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 K +IP AGLGTRMLP TK++PKEML I D+P+I Y+V E V AGI++I+ +T K AIE Sbjct: 2 KVIIPVAGLGTRMLPATKAIPKEMLTIADKPLIQYIVNECVAAGIKEIVFVTHSSKNAIE 61 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEI-GEMVDIYYVRQKKPLGLGDAILYAEKHVNGE 122 ++FD SFELE L++R K + L EV I V + +VRQ + GLG A+L + V E Sbjct: 62 NHFDTSFELETMLEKRVKRQLLDEVRSIVPNDVTLMHVRQGQAKGLGHAVLCGKAVVGKE 121 Query: 123 PFAVLLGDDII--ISKKPAIKQLIEVAER---KNTPVIGVESVPRELVSRYGIIE---GE 174 PFAV+L D I+ + P + L + +R I V VP+E VS YGI++ Sbjct: 122 PFAVVLPDVILADFTANPKTENLAAMIKRFSETQCSQIMVAPVPQEDVSNYGIVDCATDN 181 Query: 175 LIENDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQI 234 + + +I ++VEKPS + APSN+AI+GRY+ I+D+L TP G EIQLTDA+ + Sbjct: 182 IRAGETAKIAKMVEKPSIENAPSNLAIVGRYVFSATIWDLLERTPVGVGDEIQLTDAIDM 241 Query: 235 LLNKNEILAKRIEGERYDIGSKFGFVMANLKLSLRREELRNEVLKYLKSILKEI 288 L+ K + A + G +D G K G++ A ++ SLR E+ + K +K + K + Sbjct: 242 LIEKETVEAFHMTGRAFDCGDKLGYMEAFVEYSLRHEKCGQQFQKIIKELAKSL 295 >pir||S39959 exoN protein - Rhizobium meliloti >gi|397573|emb|CAA80348.1| (Z22636) ExoN [Sinorhizobium meliloti] >gi|742330|prf||2009367E ExoN protein [Rhizobium meliloti] Length = 301 Score = 210 bits (528), Expect = 2e-53 Identities = 118/286 (41%), Positives = 170/286 (59%), Gaps = 3/286 (1%) Query: 2 IRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRA 61 +RKAVIP AG GTR LP TK++PKEML IVDRPV+ Y V+EA +AGIE I+ +T + K+ Sbjct: 7 VRKAVIPVAGNGTRFLPATKAVPKEMLTIVDRPVVQYAVDEARQAGIEHIVFVTSRNKQV 66 Query: 62 IEDYFDRSFELEYYLKERGKLEALREVEE-IGEMVDIYYVRQKKPLGLGDAILYAEKHVN 120 IED+FD + EL L GK + E+E + + + RQ+ PLGLG A+ A + Sbjct: 67 IEDHFDDAPELISSLSRSGKSAQISELEAMLPAAGSVSFTRQQAPLGLGHAVWCARDLIG 126 Query: 121 GEPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGII-EGELIEND 179 EPFA+LL D + + + L+++ V+GVE E S+YGI+ +GE + + Sbjct: 127 DEPFALLLPDMVSFGARGCVAGLMDLYHEVGGNVVGVEQCAPEEASKYGIVGKGETVRHG 186 Query: 180 LYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKN 239 + + +VEKP+ +APSN + GRYIL PEIF IL G EIQLTD + L Sbjct: 187 -FSVTEMVEKPAAGKAPSNYYLNGRYILQPEIFSILAHQTRGAGNEIQLTDGMLTLSQSQ 245 Query: 240 EILAKRIEGERYDIGSKFGFVMANLKLSLRREELRNEVLKYLKSIL 285 A EG +D GSK GF+ AN+ +L R ++ + V + ++ ++ Sbjct: 246 SFHAHPYEGRTFDCGSKQGFIEANVAFALARADIGDIVFESVRDMV 291 >sp|P25520|GALU_ECOLI UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE (UDP-GLUCOSE PYROPHOSPHORYLASE) (UDPGP) (ALPHA-D-GLUCOSYL-1-PHOSPHATE URIDYLYLTRANSFERASE) (URIDINE DIPHOSPHOGLUCOSE PYROPHOSPHORYLASE) >gi|625405|pir||JC2265 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) galU [validated] - Escherichia coli >gi|42026|emb|CAA42564.1| (X59940) ORF 1 [Escherichia coli] >gi|146073|gb|AAA20118.1| (M98830) glucosephosphate uridylyltransferase [Escherichia coli] >gi|487881|gb|AAD15244.1| (L32811) UDP-glucose pyrophosphorylase [Shigella flexneri] >gi|1651627|dbj|BAA36104.1| (D90758) UTP-glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) [Escherichia coli] >gi|1651636|dbj|BAA36116.1| (D90759) UTP-glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) [Escherichia coli] >gi|1787488|gb|AAC74318.1| (AE000222) glucose-1-phosphate uridylyltransferase [Escherichia coli K12] >gi|1805513|dbj|BAA16030.1| (D90852) UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) [Escherichia coli] Length = 302 Score = 209 bits (527), Expect = 3e-53 Identities = 122/288 (42%), Positives = 178/288 (61%), Gaps = 7/288 (2%) Query: 2 IRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRA 61 ++KAVIP AGLGTRMLP TK++PKEMLP+VD+P+I YVV E + AGI +I+++T K + Sbjct: 8 VKKAVIPVAGLGTRMLPATKAIPKEMLPLVDKPLIQYVVNECIAAGITEIVLVTHSSKNS 67 Query: 62 IEDYFDRSFELEYYLKERGKLEALREVEEI-GEMVDIYYVRQKKPLGLGDAILYAEKHVN 120 IE++FD SFELE L++R K + L EV+ I V I VRQ GLG A+L A V Sbjct: 68 IENHFDTSFELEAMLEKRVKRQLLDEVQSICPPHVTIMQVRQGLAKGLGHAVLCAHPVVG 127 Query: 121 GEPFAVLLGDDIIISKKPAIKQ--LIEVAER-KNTPVIGVESVPRELVSRYGIIE---GE 174 EP AV+L D I+ + + Q L E+ R T + P V+ YG+++ E Sbjct: 128 DEPVAVILPDVILDEYESDLSQDNLAEMIRRFDETGHSQIMVEPVADVTAYGVVDCKGVE 187 Query: 175 LIENDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQI 234 L + + +VEKP APSN+AI+GRY+L +I+ +L +TPPG EIQLTDA+ + Sbjct: 188 LAPGESVPMVGVVEKPKADVAPSNLAIVGRYVLSADIWPLLAKTPPGAGDEIQLTDAIDM 247 Query: 235 LLNKNEILAKRIEGERYDIGSKFGFVMANLKLSLRREELRNEVLKYLK 282 L+ K + A ++G+ +D G+K G++ A ++ +R L E +L+ Sbjct: 248 LIEKETVEAYHMKGKSHDCGNKLGYMQAFVEYGIRHNTLGTEFKAWLE 295 >sp|P27897|CELA_ACEXY UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE (UDP-GLUCOSE PYROPHOSPHORYLASE) (UDPGP) (ALPHA-D-GLUCOSYL-1-PHOSPHATE URIDYLYLTRANSFERASE) (URIDINE DIPHOSPHOGLUCOSE PYROPHOSPHORYLASE) >gi|95298|pir||A41382 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) [validated] - Acetobacter pasteurianus >gi|141737|gb|AAA21888.1| (M76548) UDP pyrophosphorylase [Acetobacter xylinus] Length = 284 Score = 208 bits (523), Expect = 8e-53 Identities = 112/259 (43%), Positives = 158/259 (60%), Gaps = 7/259 (2%) Query: 2 IRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRA 61 ++KAV+P AGLGTR LP TK +PKEML +VDRP+I Y ++EA +AGIE+ +++ +GK + Sbjct: 5 LKKAVLPVAGLGTRFLPATKCVPKEMLTVVDRPLIQYAIDEAREAGIEEFCLVSSRGKDS 64 Query: 62 IEDYFDRSFELEYYLKERGKLEALREVEEI----GEMVDIYYVRQKKPLGLGDAILYAEK 117 + DYFD S+ELE LK R K AL+ +E G M+ V G AI A + Sbjct: 65 LIDYFDISYELEDTLKARKKTSALKALEATRVIPGTMLS---VPPAGTAGPWHAIWCARE 121 Query: 118 HVNGEPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIE 177 + +PFA+LL DD++ SKK I QL+EV + V+ V VPRE YGI++ + Sbjct: 122 FIGNDPFAILLPDDVVQSKKSCIGQLVEVYNKTGGNVLAVTEVPREQTGSYGILDVGKDD 181 Query: 178 NDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLN 237 +K LVEKP PK+APS +++IGRY+L ++ L + G GE+QLTDA+ + Sbjct: 182 GKTVEVKGLVEKPDPKDAPSTLSVIGRYVLTADVLKHLAKLEKGAGGEVQLTDAMAKTIG 241 Query: 238 KNEILAKRIEGERYDIGSK 256 R EG+R+D GSK Sbjct: 242 HVPFHGYRYEGKRFDCGSK 260 >sp|P33696|EXON_RHIME UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE (UDP-GLUCOSE PYROPHOSPHORYLASE) (UDPGP) (ALPHA-D-GLUCOSYL-1-PHOSPHATE URIDYLYLTRANSFERASE) (URIDINE DIPHOSPHOGLUCOSE PYROPHOSPHORYLASE) >gi|538709|pir||D49349 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) exoN [similarity] - Rhizobium meliloti >gi|393242|gb|AAA16043.1| (L20758) exoN [Sinorhizobium meliloti] Length = 320 Score = 205 bits (517), Expect = 4e-52 Identities = 116/269 (43%), Positives = 160/269 (59%), Gaps = 3/269 (1%) Query: 2 IRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRA 61 +RKAVIP AG GTR LP TK++PKEML IVDRPV+ Y V+EA +AGIE I+ +T + K+ Sbjct: 7 VRKAVIPVAGNGTRFLPATKAVPKEMLTIVDRPVVQYAVDEARQAGIEHIVFVTSRNKQV 66 Query: 62 IEDYFDRSFELEYYLKERGKLEALREVEE-IGEMVDIYYVRQKKPLGLGDAILYAEKHVN 120 IED+FD + EL L GK + E+E + + + RQ+ PLGLG A+ A + Sbjct: 67 IEDHFDDAPELISSLSRSGKSAQISELEAMLPAAGSVSFTRQQAPLGLGHAVWCARDLIG 126 Query: 121 GEPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGII-EGELIEND 179 EPFA+LL D + + + L+++ V+GVE E S+YGI+ +GE + + Sbjct: 127 DEPFALLLPDMVSFGARGCVAGLMDLYHEVGGNVVGVEQCAPEEASKYGIVGKGETVRHG 186 Query: 180 LYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKN 239 + + +VEKP+ +APSN + GRYIL PEIF IL G EIQLTD + L Sbjct: 187 -FSVTEMVEKPAAGKAPSNYYLNGRYILQPEIFSILAHQTRGAGNEIQLTDGMLTLSQSQ 245 Query: 240 EILAKRIEGERYDIGSKFGFVMANLKLSL 268 A EG +D GSK GF+ AN+ +L Sbjct: 246 SFHAHPYEGRTFDCGSKQGFIEANVAFAL 274 >pir||S78541 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) galF [similarity] - Escherichia coli (strain VW187) >gi|799231|gb|AAC63611.1| (AF125322) GalF [Escherichia coli] Length = 302 Score = 194 bits (487), Expect = 1e-48 Identities = 123/298 (41%), Positives = 176/298 (58%), Gaps = 12/298 (4%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPI-VDRPVIHYVVEEAVKAGIEDILIITGKGKRAI 62 KAVIP AGLG MLP TK++PKEMLPI VD+P+I Y+V+E V AGI++IL++T K A+ Sbjct: 5 KAVIPVAGLGMHMLPATKAIPKEMLPIPVDKPMIQYIVDEIVAAGIKEILLVTHASKNAV 64 Query: 63 EDYFDRSFELEYYLKERGKLEALREVEEIGEM-VDIYYVRQKKPLGLGDAILYAEKHVNG 121 E++FD S+ELE L++R K + L EV+ I V I VRQ +PLGLG +IL A + Sbjct: 65 ENHFDTSYELESLLEQRVKRQLLAEVQSICPPGVTIMNVRQGEPLGLGHSILCARPAIGD 124 Query: 122 EPFAVLLGDDII--ISKKPAIKQLIEVAERKNTP---VIGVESVPRELVSRYGIIEGELI 176 PF V+L D +I S P L + R N + + +P +L S Y +I+ + Sbjct: 125 NPFVVVLPDVVIDDASADPLRYNLAAMIARFNETGRSQVLAKRMPGDL-SEYSVIQTKEP 183 Query: 177 ---ENDLYRIKRLVEKPS-PKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDAL 232 E + RI +EKP P+ S+I +GRY+L +I+ L T PG G IQLTDA+ Sbjct: 184 LDREGKVSRIVEFIEKPDQPQTLDSDIMAVGRYVLSADIWPELERTQPGAWGRIQLTDAI 243 Query: 233 QILLNKNEILAKRIEGERYDIGSKFGFVMANLKLSLRREELRNEVLKYLKSILKEISN 290 L K + A + G+ YD G K G++ A +K LR + + LK ++ +L E++N Sbjct: 244 AELAKKQSVDAMLMTGDSYDCGKKMGYMQAFVKYGLRNLKEGAKFLKGIEKLLSEVTN 301 >sp|P78083|GALF_ECOLI UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE (UDP-GLUCOSE PYROPHOSPHORYLASE) (UDPGP) (ALPHA-D-GLUCOSYL-1-PHOSPHATE URIDYLYLTRANSFERASE) (URIDINE DIPHOSPHOGLUCOSE PYROPHOSPHORYLASE) >gi|7428086|pir||A64970 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) galF [similarity] - Escherichia coli (strain K-12) >gi|1736745|dbj|BAA15896.1| (D90842) UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) (UDP-glucose pyrophosphorylase) (UDPGP) (a-d-glucosyl-1-phosphate uridylyltransferase) (Uridine diphosphoglucose pyrophosphorylase). [Escherichia coli] >gi|1788355|gb|AAC75103.1| (AE000295) homolog of Salmonella UTP--glucose-1-P uridyltransferase, probably a UDP-gal transferase [Escherichia coli K12] >gi|3041819|gb|AAC77853.1| (U38473) possible glucose-1-P uridylyl transferase isozyme [Escherichia coli] >gi|4867914|dbj|BAA77723.1| (AB008676) UTP-glucose-1-phosphate uridylyltransferase [Escherichia coli] Length = 297 Score = 192 bits (483), Expect = 4e-48 Identities = 121/294 (41%), Positives = 172/294 (58%), Gaps = 11/294 (3%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 KAVIP AGLG MLP TK++PKEMLPIVD+P+I Y+V+E V AGI++IL++T K A+E Sbjct: 5 KAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIVDEIVAAGIKEILLVTHASKNAVE 64 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEI-GEMVDIYYVRQKKPLGLGDAILYAEKHVNGE 122 ++FD S+ELE L++R K + L EV+ I V I VRQ +PLGLG +IL A + Sbjct: 65 NHFDTSYELESLLEQRVKRQLLAEVQSICPPGVTIMNVRQGEPLGLGHSILCARPAIGDN 124 Query: 123 PFAVLLGDDII--ISKKPAIKQLIEVAERKN---TPVIGVESVPRELVSRYGIIEGEL-- 175 PF V+L D +I S P L + R N + + +P +L S Y +I+ + Sbjct: 125 PFVVVLPDVVIDDASADPLRYNLAAMIARFNETGRSQVLAKRMPGDL-SEYSVIQTKEPL 183 Query: 176 -IENDLYRIKRLVEKP-SPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQ 233 E + RI +EKP P+ S+I +GRY+L +I+ L T PG G IQLTDA+ Sbjct: 184 DREGKVSRIVEFIEKPDQPQTLDSDIMAVGRYVLSADIWPELERTQPGAWGRIQLTDAIA 243 Query: 234 ILLNKNEILAKRIEGERYDIGSKFGFVMANLKLSLRREELRNEVLKYLKSILKE 287 L K + A + G+ YD G K G++ A +K LR + + K ++ +L E Sbjct: 244 ELAKKQSVDAMLMTGDSYDCGKKMGYMQAFVKYGLRNLKEGAKFRKGIEKLLSE 297 >pir||G70125 probable UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) BB0207 [similarity] - Lyme disease spirochete >gi|2688101|gb|AAC66596.1| (AE001131) UTP--glucose-1-phosphate uridylyltransferase (gtaB) [Borrelia burgdorferi] Length = 278 Score = 192 bits (483), Expect = 4e-48 Identities = 106/277 (38%), Positives = 171/277 (61%), Gaps = 7/277 (2%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 K +I AAG GTR LPITK++PKEMLPI+++P I Y+++E + +GI+DIL+I+ + K+ +E Sbjct: 2 KGIILAAGYGTRFLPITKTIPKEMLPILNKPAIDYIIQEFIDSGIKDILLISSRRKKVLE 61 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 DYFDR ELE + K + L ++ + ++I ++RQK+ LG G+A+LYA+ +N EP Sbjct: 62 DYFDREIELENIFLKENKKDELEKIR--SKKINISFIRQKEMLGTGNALLYAKPWINREP 119 Query: 124 FAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLYRI 183 V DD+ I P QLI++ E+ +I + P E ++RYG+I+ + D + Sbjct: 120 VVVAYPDDLCIGNPPLSLQLIKLYEKTGKNIISIIENP-ENINRYGVID---LYKDEIHV 175 Query: 184 KRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRE-TPPGRDGEIQLTDALQILLNKNEIL 242 K ++EKP PSN A IGR++ E F+ L E + GE AL+ L+++ ++L Sbjct: 176 KNIIEKPKIGSEPSNKASIGRFLYNYEFFEHLEEGFKLHKKGEYYHIYALKKLMDQKKVL 235 Query: 243 AKRIEGERYDIGSKFGFVMANLKLSLRREELRNEVLK 279 K IEG+R DIG+ G++ A + + + ++L + K Sbjct: 236 YKNIEGKRIDIGTLEGYLEAIINSAKKDKKLMGIIKK 272 >sp|P37776|GALF_SHIFL UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE (UDP-GLUCOSE PYROPHOSPHORYLASE) (UDPGP) (ALPHA-D-GLUCOSYL-1-PHOSPHATE URIDYLYLTRANSFERASE) (URIDINE DIPHOSPHOGLUCOSE PYROPHOSPHORYLASE) >gi|541219|pir||S41533 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) galF [similarity] - Shigella flexneri >gi|454897|emb|CAA50766.1| (X71970) galF [Shigella flexneri] Length = 297 Score = 189 bits (475), Expect = 3e-47 Identities = 119/294 (40%), Positives = 171/294 (57%), Gaps = 11/294 (3%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 KAVIP AGLG MLP TK++PKEMLP D+P+I Y+V+E V AGI++IL++T K A+E Sbjct: 5 KAVIPVAGLGMHMLPATKAIPKEMLPTADKPMIQYIVDEIVAAGIKEILLVTHASKNAVE 64 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEI-GEMVDIYYVRQKKPLGLGDAILYAEKHVNGE 122 ++FD S+ELE L++R K + L EV+ I V I VRQ +PLGLG +IL A + Sbjct: 65 NHFDTSYELESLLEQRVKRQLLAEVQSICPPGVIIMNVRQGEPLGLGHSILCARPAIGDN 124 Query: 123 PFAVLLGDDII--ISKKPAIKQLIEVAERKN---TPVIGVESVPRELVSRYGIIEGEL-- 175 PF V+L D +I S P L + R N + + +P +L S Y +I+ + Sbjct: 125 PFVVVLPDVVIDDASADPLRYNLAAMIARFNETGRSQVLAKRMPGDL-SEYSVIQTKEPL 183 Query: 176 -IENDLYRIKRLVEKP-SPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQ 233 E + RI +EKP P+ S+I +GRY+L +I+ L T PG G IQLTDA+ Sbjct: 184 DREGKVSRIVEFIEKPDQPQTLDSDIMAVGRYVLSADIWPELERTQPGAWGRIQLTDAIA 243 Query: 234 ILLNKNEILAKRIEGERYDIGSKFGFVMANLKLSLRREELRNEVLKYLKSILKE 287 L K + A + G+ YD G K G++ A +K LR + ++ K ++ +L E Sbjct: 244 ELAKKQSVDAMLMTGDSYDCGKKMGYMQAFVKYGLRNLKEGSKFRKGIEKLLSE 297 >emb|CAC11046.1| (AJ286776) UTP-glucose-1-phosphate uridylyltransferase [Streptococcus pneumoniae] Length = 198 Score = 189 bits (475), Expect = 3e-47 Identities = 104/200 (52%), Positives = 139/200 (69%), Gaps = 9/200 (4%) Query: 47 GIEDILIITGKGKRAIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPL 106 GIEDIL++TGK KR+IED+FD +FELEY LKE+GK + L+ V+E M ++++RQ P Sbjct: 1 GIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDEATGM-RLHFIRQTHPR 59 Query: 107 GLGDAILYAEKHVNGEPFAVLLGDDIII----SKKPAIKQLIEVAERKNTPVIGVESVPR 162 GLGDA+L A+ V EPF V+LGDD++ + P KQL+ E+ + I V VP Sbjct: 60 GLGDAVLQAKAFVGNEPFVVMLGDDLMDITDENAVPLTKQLMNDYEKTHASTIAVMPVPH 119 Query: 163 ELVSRYGII--EGELIENDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPP 220 E VS YG+I +GE I N LY ++ VEKP+P++APS++AIIGRY+L PEIFDIL + P Sbjct: 120 EDVSSYGVIAPQGEGI-NGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEIFDILEKQAP 178 Query: 221 GRDGEIQLTDALQILLNKNE 240 G EIQLTDA+ LNK + Sbjct: 179 GAGNEIQLTDAID-TLNKTQ 197 >emb|CAC11047.1| (AJ286777) UTP-glucose-1-phosphate uridylyltransferase [Streptococcus pneumoniae] Length = 198 Score = 189 bits (474), Expect = 4e-47 Identities = 104/200 (52%), Positives = 139/200 (69%), Gaps = 9/200 (4%) Query: 47 GIEDILIITGKGKRAIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPL 106 GIEDIL++TGK KR+IED+FD +FELEY LKE+GK + L+ V+E M ++++RQ P Sbjct: 1 GIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDEATGM-RLHFIRQTHPR 59 Query: 107 GLGDAILYAEKHVNGEPFAVLLGDDIII----SKKPAIKQLIEVAERKNTPVIGVESVPR 162 GLGDA+L A+ V EPF V+LGDD++ + P KQL+ ER + I V VP Sbjct: 60 GLGDAVLQAKAFVGNEPFVVMLGDDLMDITDENAVPLTKQLMNDYERTHASTIAVMPVPH 119 Query: 163 ELVSRYGII--EGELIENDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPP 220 E VS YG+I +GE I N LY ++ VEKP+P++APS++AIIGRY+L PEIF+IL + P Sbjct: 120 EDVSAYGVIAPQGEGI-NGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEIFEILEKQAP 178 Query: 221 GRDGEIQLTDALQILLNKNE 240 G EIQLTDA+ LNK + Sbjct: 179 GAGNEIQLTDAID-TLNKTQ 197 >emb|CAC11048.1| (AJ286778) UTP-glucose-1-phosphate uridylyltransferase [Streptococcus pneumoniae] Length = 198 Score = 189 bits (474), Expect = 4e-47 Identities = 106/200 (53%), Positives = 139/200 (69%), Gaps = 9/200 (4%) Query: 47 GIEDILIITGKGKRAIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPL 106 GIEDIL++TGK KR+IED+FD +FELEY LKE+GK + L+ V+E M ++++RQ P Sbjct: 1 GIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDEATGM-RLHFIRQTHPR 59 Query: 107 GLGDAILYAEKHVNGEPFAVLLGDDI--IISKK--PAIKQLIEVAERKNTPVIGVESVPR 162 GLGDA+L A+ V EPF V+LGDD+ I + K P KQL+ E+ + I V VP Sbjct: 60 GLGDAVLQAKAFVGNEPFVVMLGDDLMDITNDKAIPLTKQLMNDYEKTHASTIAVMPVPH 119 Query: 163 ELVSRYGII--EGELIENDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPP 220 E VS YG+I +GE I N LY ++ VEKP+P+EAPS++AIIGRY+L PEIF+IL P Sbjct: 120 EDVSSYGVIAPQGEGI-NGLYSVETFVEKPAPEEAPSDLAIIGRYLLTPEIFEILENQAP 178 Query: 221 GRDGEIQLTDALQILLNKNE 240 G EIQLTDA+ LNK + Sbjct: 179 GAGNEIQLTDAID-TLNKTQ 197 >sp|P26390|GALF_SALTY UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE (UDP-GLUCOSE PYROPHOSPHORYLASE) (UDPGP) (ALPHA-D-GLUCOSYL-1-PHOSPHATE URIDYLYLTRANSFERASE) (URIDINE DIPHOSPHOGLUCOSE PYROPHOSPHORYLASE) >gi|47888|emb|CAA40114.1| (X56793) putative glucose-1-phosphate uridylyltransferase [Salmonella enterica] Length = 297 Score = 188 bits (473), Expect = 6e-47 Identities = 120/293 (40%), Positives = 171/293 (57%), Gaps = 9/293 (3%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 KAVIP AGLG MLP TK++PKEMLPIVD+P+I Y+V+E V AGI++I+++T K A+E Sbjct: 5 KAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIVDEIVAAGIKEIVLVTHASKNAVE 64 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEI-GEMVDIYYVRQKKPLGLGDAILYAEKHVNGE 122 ++FD S+ELE L++R K + L EV+ I V I VRQ +PLGLG +IL A V Sbjct: 65 NHFDTSYELESLLEQRVKRQLLAEVQSICPPGVTIMNVRQAQPLGLGHSILCARPVVGDN 124 Query: 123 PFAVLLGDDII--ISKKPAIKQLIEVAERKNTPVIGVESVPREL--VSRYGIIE-GELIE 177 PF V+L D II + P L + R N R +S Y +I+ E ++ Sbjct: 125 PFIVVLPDIIIDDATADPLRYNLAAMVARFNETGRSQVLAKRMKGDLSEYSVIQTKEPLD 184 Query: 178 ND--LYRIKRLVEKP-SPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQI 234 N+ + RI +EKP P+ S++ +GRY+L +I+ L T PG G IQLTDA+ Sbjct: 185 NEGKVSRIVEFIEKPDQPQTLDSDLMAVGRYVLSADIWAELERTEPGAWGRIQLTDAIAE 244 Query: 235 LLNKNEILAKRIEGERYDIGSKFGFVMANLKLSLRREELRNEVLKYLKSILKE 287 L K + A + G+ YD G K G++ A +K LR + + K ++ +L E Sbjct: 245 LAKKQSVDAMLMTGDSYDCGKKMGYMQAFVKYGLRNLKEGAKFRKSIEQLLHE 297 >pir||S15298 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) galF [similarity] - Salmonella typhimurium Length = 297 Score = 188 bits (473), Expect = 6e-47 Identities = 120/293 (40%), Positives = 171/293 (57%), Gaps = 9/293 (3%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 KAVIP AGLG MLP TK++PKEMLPIVD+P+I Y+V+E V AGI++I+++T K A+E Sbjct: 5 KAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIVDEIVAAGIKEIVLVTHHSKNAVE 64 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEI-GEMVDIYYVRQKKPLGLGDAILYAEKHVNGE 122 ++FD S+ELE L++R K + L EV+ I V I VRQ +PLGLG +IL A V Sbjct: 65 NHFDTSYELESLLEQRVKRQLLAEVQSICPPGVTIMNVRQAQPLGLGHSILCARPVVGDN 124 Query: 123 PFAVLLGDDII--ISKKPAIKQLIEVAERKNTPVIGVESVPREL--VSRYGIIE-GELIE 177 PF V+L D II + P L + R N R +S Y +I+ E ++ Sbjct: 125 PFIVVLPDIIIDDATADPLRYNLAAMVARFNETGRSQVLAKRMKGDLSEYSVIQTKEPLD 184 Query: 178 ND--LYRIKRLVEKP-SPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQI 234 N+ + RI +EKP P+ S++ +GRY+L +I+ L T PG G IQLTDA+ Sbjct: 185 NEGKVSRIVEFIEKPDQPQTLDSDLMAVGRYVLSADIWAELERTEPGAWGRIQLTDAIAE 244 Query: 235 LLNKNEILAKRIEGERYDIGSKFGFVMANLKLSLRREELRNEVLKYLKSILKE 287 L K + A + G+ YD G K G++ A +K LR + + K ++ +L E Sbjct: 245 LAKKQSVDAMLMTGDSYDCGKKMGYMQAFVKYGLRNLKEGAKFRKSIEQLLHE 297 >sp|Q48447|GALF_KLEPN UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE (UDP-GLUCOSE PYROPHOSPHORYLASE) (UDPGP) (ALPHA-D-GLUCOSYL-1-PHOSPHATE URIDYLYLTRANSFERASE) (URIDINE DIPHOSPHOGLUCOSE PYROPHOSPHORYLASE) >gi|747657|dbj|BAA04772.1| (D21242) ORF1 [Klebsiella pneumoniae] Length = 298 Score = 188 bits (472), Expect = 8e-47 Identities = 120/293 (40%), Positives = 171/293 (57%), Gaps = 14/293 (4%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 KAVIP AGLG MLP TK++PKEMLPIVD+P+I Y+V+E V AGI++I+++T K A+E Sbjct: 7 KAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIVDEIVAAGIKEIVLVTHSSKNAVE 66 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEM-VDIYYVRQKKPLGLGDAILYAEKHVNGE 122 ++FD S+ELE L++R K + L EV+ I V I VRQ +PLGLG +IL A V Sbjct: 67 NHFDTSYELEALLEQRVKRQLLAEVQAICPPGVTIMNVRQAQPLGLGHSILCARPVVGDN 126 Query: 123 PFAVLLGDDIII--SKKPAIKQLIEVAERKNTP---VIGVESVPRELVSRYGIIEGE--- 174 PF V+L D I+ + P L + R N + + +P +L S Y +I+ + Sbjct: 127 PFVVVLPDIILDGGTADPLRYNLAAMIARFNETGRSQVLAKRMPGDL-SEYSVIQTKEPM 185 Query: 175 LIENDLYRIKRLVEKPS-PKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQ 233 + E + RI +EKP P+ S++ +GRY+L +I+ L T PG G IQLTDA+ Sbjct: 186 VAEGQVARIVEFIEKPDEPQTLDSDLMAVGRYVLSADIWAELERTEPGAWGRIQLTDAIA 245 Query: 234 ILLNKNEILAKRIEGERYDIGSKFGFVMANLKLSLRREELRNEVLKYLKSILK 286 L K + A + GE YD G K G++ A + +R E K+ +SI K Sbjct: 246 ELAKKQSVDAMLMTGESYDCGKKMGYMQAFVTYGMRN---LKEGAKFRESIKK 295 >pir||A56146 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) [similarity] - Klebsiella pneumoniae Length = 296 Score = 188 bits (472), Expect = 8e-47 Identities = 120/293 (40%), Positives = 171/293 (57%), Gaps = 14/293 (4%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 KAVIP AGLG MLP TK++PKEMLPIVD+P+I Y+V+E V AGI++I+++T K A+E Sbjct: 5 KAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIVDEIVAAGIKEIVLVTHSSKNAVE 64 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEM-VDIYYVRQKKPLGLGDAILYAEKHVNGE 122 ++FD S+ELE L++R K + L EV+ I V I VRQ +PLGLG +IL A V Sbjct: 65 NHFDTSYELEALLEQRVKRQLLAEVQAICPPGVTIMNVRQAQPLGLGHSILCARPVVGDN 124 Query: 123 PFAVLLGDDIII--SKKPAIKQLIEVAERKNTP---VIGVESVPRELVSRYGIIEGE--- 174 PF V+L D I+ + P L + R N + + +P +L S Y +I+ + Sbjct: 125 PFVVVLPDIILDGGTADPLRYNLAAMIARFNETGRSQVLAKRMPGDL-SEYSVIQTKEPM 183 Query: 175 LIENDLYRIKRLVEKPS-PKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQ 233 + E + RI +EKP P+ S++ +GRY+L +I+ L T PG G IQLTDA+ Sbjct: 184 VAEGQVARIVEFIEKPDEPQTLDSDLMAVGRYVLSADIWAELERTEPGAWGRIQLTDAIA 243 Query: 234 ILLNKNEILAKRIEGERYDIGSKFGFVMANLKLSLRREELRNEVLKYLKSILK 286 L K + A + GE YD G K G++ A + +R E K+ +SI K Sbjct: 244 ELAKKQSVDAMLMTGESYDCGKKMGYMQAFVTYGMRN---LKEGAKFRESIKK 293 >emb|CAC11027.1| (AJ286782) UTP-glucose-1-phosphate uridylyltransferase [Streptococcus gordonii] Length = 198 Score = 187 bits (471), Expect = 1e-46 Identities = 105/200 (52%), Positives = 138/200 (68%), Gaps = 9/200 (4%) Query: 47 GIEDILIITGKGKRAIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPL 106 GIEDIL++TGK KR+IED+FD +FELEY LKE+GK + L+ V+E + ++++RQ P Sbjct: 1 GIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKDDLLKLVDETTG-IGLHFIRQSHPR 59 Query: 107 GLGDAILYAEKHVNGEPFAVLLGDDI--IISKK--PAIKQLIEVAERKNTPVIGVESVPR 162 GLGDA+L A+ V EPF V+LGDD+ I + K P KQL+ E + I V VP Sbjct: 60 GLGDAVLQAKAFVGNEPFVVMLGDDLMDITNDKAMPLTKQLMNDYEATHASTIAVMQVPH 119 Query: 163 ELVSRYGII--EGELIENDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPP 220 E VS YG+I +GE + N LY +++ VEKPSP+EAPS++AIIGRY+L PEIF IL P Sbjct: 120 EEVSSYGVIAPQGEGL-NGLYSVEKFVEKPSPEEAPSDLAIIGRYLLTPEIFKILENQAP 178 Query: 221 GRDGEIQLTDALQILLNKNE 240 G EIQLTDA+ LNK + Sbjct: 179 GAGNEIQLTDAID-TLNKTQ 197 >emb|CAC11044.1| (AJ286774) UTP-glucose-1-phosphate uridylyltransferase [Streptococcus pneumoniae] Length = 198 Score = 187 bits (470), Expect = 1e-46 Identities = 106/202 (52%), Positives = 137/202 (67%), Gaps = 13/202 (6%) Query: 47 GIEDILIITGKGKRAIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPL 106 GIEDIL++TGK KR+IED+FD +FELEY LKE+GK + L+ VEE M ++++RQ P Sbjct: 1 GIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVEEATGM-RLHFIRQTHPR 59 Query: 107 GLGDAILYAEKHVNGEPFAVLLGDDI--IISKK--PAIKQLIEVAERKNTPVIGVESVPR 162 GLGDAIL A+ V EPF V+LGDD+ I +K P KQL+ E+ + I V VP Sbjct: 60 GLGDAILQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMNDYEKTHASTIAVMPVPH 119 Query: 163 ELVSRYGII----EGELIENDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRET 218 E VS YG+I EG N LY ++ VEKP+P+E PS++AIIGRY+L PEIF+IL + Sbjct: 120 EDVSSYGVIAPQDEGS---NGLYSVETFVEKPAPEETPSDLAIIGRYLLTPEIFEILEKQ 176 Query: 219 PPGRDGEIQLTDALQILLNKNE 240 PG EIQLTDA+ LNK + Sbjct: 177 APGAGNEIQLTDAID-TLNKTQ 197 >emb|CAC11038.1| (AJ286767) UTP-glucose-1-phosphate uridylyltransferase [Streptococcus pneumoniae] >gi|10638174|emb|CAC11041.1| (AJ286770) UTP-glucose-1-phosphate uridylyltransferase [Streptococcus pneumoniae] Length = 198 Score = 186 bits (468), Expect = 2e-46 Identities = 103/200 (51%), Positives = 141/200 (70%), Gaps = 9/200 (4%) Query: 47 GIEDILIITGKGKRAIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPL 106 GIEDIL++TGK KR+IED+FD +FELEY LKE+GK + L+ V+E M ++++RQ P Sbjct: 1 GIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGM-RLHFIRQTHPR 59 Query: 107 GLGDAILYAEKHVNGEPFAVLLGDDI--IISKK--PAIKQLIEVAERKNTPVIGVESVPR 162 GLGDA+L A+ V EPF V+LGDD+ I +K P KQL++ ER + I V VP Sbjct: 60 GLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHASTIAVMPVPH 119 Query: 163 ELVSRYGII--EGELIENDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPP 220 + VS YG+I +GE ++ LY ++ VEKP+P++APS++AIIGRY+L PEIF+IL + P Sbjct: 120 DEVSAYGVIAPQGEG-KDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEIFEILEKQAP 178 Query: 221 GRDGEIQLTDALQILLNKNE 240 G EIQLTDA+ LNK + Sbjct: 179 GAGNEIQLTDAID-TLNKTQ 197 >emb|CAC11039.1| (AJ286768) UTP-glucose-1-phosphate uridylyltransferase [Streptococcus pneumoniae] Length = 198 Score = 186 bits (468), Expect = 2e-46 Identities = 102/200 (51%), Positives = 141/200 (70%), Gaps = 9/200 (4%) Query: 47 GIEDILIITGKGKRAIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPL 106 GIEDIL++TGK KR+IED+FD +FELEY LKE+GK++ L+ V++ +M ++++RQ P Sbjct: 1 GIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKIDLLKLVDKTTDM-RLHFIRQTHPR 59 Query: 107 GLGDAILYAEKHVNGEPFAVLLGDDI--IISKK--PAIKQLIEVAERKNTPVIGVESVPR 162 GLGDA+L A+ V EPF V+LGDD+ I +K P KQL++ ER + I V VP Sbjct: 60 GLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHASTIAVMPVPH 119 Query: 163 ELVSRYGII--EGELIENDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPP 220 + VS YG+I +GE ++ LY ++ VEKP+P++APS++AIIGRY+L PEIF IL P Sbjct: 120 DEVSAYGVIAPQGEG-KDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEIFQILENQAP 178 Query: 221 GRDGEIQLTDALQILLNKNE 240 G EIQLTDA+ LNK + Sbjct: 179 GAGNEIQLTDAID-TLNKTQ 197 >emb|CAC11043.1| (AJ286772) UTP-glucose-1-phosphate uridylyltransferase [Streptococcus pneumoniae] Length = 198 Score = 186 bits (468), Expect = 2e-46 Identities = 103/200 (51%), Positives = 141/200 (70%), Gaps = 9/200 (4%) Query: 47 GIEDILIITGKGKRAIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPL 106 GIEDIL++TGK KR+IED+FD +FELEY LKE+GK + L+ V+E M ++++RQ P Sbjct: 1 GIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGM-RLHFIRQTHPR 59 Query: 107 GLGDAILYAEKHVNGEPFAVLLGDDI--IISKK--PAIKQLIEVAERKNTPVIGVESVPR 162 GLGDA+L A+ V EPF V+LGDD+ I +K P KQL++ ER + I V VP Sbjct: 60 GLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKTVPLTKQLMDDYERTHASTIAVMPVPH 119 Query: 163 ELVSRYGII--EGELIENDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPP 220 + VS YG+I +GE ++ LY ++ VEKP+P++APS++AIIGRY+L PEIF+IL + P Sbjct: 120 DEVSAYGVIAPQGEG-KDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEIFEILEKQAP 178 Query: 221 GRDGEIQLTDALQILLNKNE 240 G EIQLTDA+ LNK + Sbjct: 179 GAGNEIQLTDAID-TLNKTQ 197 >emb|CAC11042.1| (AJ286771) UTP-glucose-1-phosphate uridylyltransferase [Streptococcus pneumoniae] Length = 198 Score = 186 bits (467), Expect = 3e-46 Identities = 103/200 (51%), Positives = 141/200 (70%), Gaps = 9/200 (4%) Query: 47 GIEDILIITGKGKRAIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPL 106 GIEDIL++TGK KR+IED+FD +FELEY LKE+GK + L+ V+E M ++++RQ P Sbjct: 1 GIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGM-RLHFIRQTHPR 59 Query: 107 GLGDAILYAEKHVNGEPFAVLLGDDI--IISKK--PAIKQLIEVAERKNTPVIGVESVPR 162 GLGDA+L A+ V EPF V+LGDD+ I +K P KQLI+ +R + I V VP Sbjct: 60 GLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLIDDYKRTHASTIAVMPVPH 119 Query: 163 ELVSRYGII--EGELIENDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPP 220 + VS YG+I +GE ++ LY ++ VEKP+P++APS++AIIGRY+L PEIF+IL + P Sbjct: 120 DEVSAYGVIAPQGEG-KDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEIFEILEKQAP 178 Query: 221 GRDGEIQLTDALQILLNKNE 240 G EIQLTDA+ LNK + Sbjct: 179 GAGNEIQLTDAID-TLNKTQ 197 >emb|CAC11030.1| (AJ286773) UTP-glucose-1-phosphate uridylyltransferase [Streptococcus pneumoniae] >gi|10638212|emb|CAC11050.1| (AJ286783) UTP-glucose-1-phosphate uridylyltransferase [Streptococcus sanguinis] >gi|10638215|emb|CAC11051.1| (AJ286784) UTP-glucose-1-phosphate uridylyltransferase [Streptococcus salivarius] >gi|10638218|emb|CAC11052.1| (AJ286785) UTP-glucose-1-phosphate uridylyltransferase [Streptococcus sobrinus] Length = 198 Score = 186 bits (467), Expect = 3e-46 Identities = 105/202 (51%), Positives = 137/202 (66%), Gaps = 13/202 (6%) Query: 47 GIEDILIITGKGKRAIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPL 106 GIEDIL++TGK KR+IED+FD +FELEY LKE+GK + L+ V+E M ++++RQ P Sbjct: 1 GIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDEATGM-RLHFIRQTHPR 59 Query: 107 GLGDAILYAEKHVNGEPFAVLLGDDI--IISKK--PAIKQLIEVAERKNTPVIGVESVPR 162 GLGDAIL A+ V EPF V+LGDD+ I +K P KQL+ E+ + I V VP Sbjct: 60 GLGDAILQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMNDYEKTHASTIAVMPVPH 119 Query: 163 ELVSRYGII----EGELIENDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRET 218 E VS YG+I EG N LY ++ VEKP+P+E PS++AIIGRY+L PEIF+IL + Sbjct: 120 EDVSSYGVIAPQDEGS---NGLYSVETFVEKPAPEETPSDLAIIGRYLLTPEIFEILEKQ 176 Query: 219 PPGRDGEIQLTDALQILLNKNE 240 PG EIQLTDA+ LNK + Sbjct: 177 APGAGNEIQLTDAID-TLNKTQ 197 >emb|CAC11028.1| (AJ286780) UTP-glucose-1-phosphate uridylyltransferase [Streptococcus mitis] Length = 198 Score = 185 bits (466), Expect = 4e-46 Identities = 103/200 (51%), Positives = 136/200 (67%), Gaps = 9/200 (4%) Query: 47 GIEDILIITGKGKRAIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPL 106 GIEDIL++TGK KR+IED+FD +FELEY LKE+GK + L+ V+E + ++++RQ P Sbjct: 1 GIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKHDLLKLVDETTG-IRLHFIRQSHPR 59 Query: 107 GLGDAILYAEKHVNGEPFAVLLGDDIIISKK----PAIKQLIEVAERKNTPVIGVESVPR 162 GLGDA+L A+ V EPF V+LGDD++ P KQL+ E + I V VP Sbjct: 60 GLGDAVLQAKAFVGNEPFVVMLGDDLMDITDDHAVPLTKQLMNDYETTHASTIAVMPVPH 119 Query: 163 ELVSRYGII--EGELIENDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPP 220 E VS YG+I +GE I N LY ++ VEKP+P+EAPS++AIIGRY+L PEIF+IL P Sbjct: 120 EEVSAYGVIAPQGEGI-NGLYSVETFVEKPAPEEAPSDLAIIGRYLLTPEIFEILENQAP 178 Query: 221 GRDGEIQLTDALQILLNKNE 240 G EIQLTDA+ LNK + Sbjct: 179 GAGNEIQLTDAID-TLNKTQ 197 >emb|CAC11029.1| (AJ286781) UTP-glucose-1-phosphate uridylyltransferase [Streptococcus oralis] Length = 198 Score = 185 bits (466), Expect = 4e-46 Identities = 103/200 (51%), Positives = 140/200 (69%), Gaps = 9/200 (4%) Query: 47 GIEDILIITGKGKRAIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPL 106 GIEDIL++TGK KR+IED+FD +FELEY LKE+GK + L+ V+E M ++++RQ P Sbjct: 1 GIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGM-RLHFIRQTHPR 59 Query: 107 GLGDAILYAEKHVNGEPFAVLLGDDI--IISKK--PAIKQLIEVAERKNTPVIGVESVPR 162 GLGDA+L A+ V EPF V+LGDD+ I ++K P KQL++ ER + I V VP Sbjct: 60 GLGDAVLQAKAFVGNEPFVVMLGDDLMDITNEKAVPLTKQLMDDYERTHASTIAVMPVPH 119 Query: 163 ELVSRYGII--EGELIENDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPP 220 + VS YG+I +GE ++ LY ++ VEKP+P++APS++AIIGRY+L PEIF IL P Sbjct: 120 DEVSAYGVIAPQGEG-KDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEIFQILENQAP 178 Query: 221 GRDGEIQLTDALQILLNKNE 240 G EIQLTDA+ LNK + Sbjct: 179 GAGNEIQLTDAID-TLNKTQ 197 >emb|CAC11034.1| (AJ286763) UTP-glucose-1-phosphate uridylyltransferase [Streptococcus pneumoniae] >gi|10638159|emb|CAC11036.1| (AJ286765) UTP-glucose-1-phosphate uridylyltransferase [Streptococcus pneumoniae] >gi|10638162|emb|CAC11037.1| (AJ286766) UTP-glucose-1-phosphate uridylyltransferase [Streptococcus pneumoniae] Length = 198 Score = 185 bits (465), Expect = 5e-46 Identities = 102/200 (51%), Positives = 140/200 (70%), Gaps = 9/200 (4%) Query: 47 GIEDILIITGKGKRAIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPL 106 GIEDIL++TGK KR+IED+FD +FELEY LKE+GK + L+ V++ +M ++++RQ P Sbjct: 1 GIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDKTTDM-RLHFIRQTHPR 59 Query: 107 GLGDAILYAEKHVNGEPFAVLLGDDI--IISKK--PAIKQLIEVAERKNTPVIGVESVPR 162 GLGDA+L A+ V EPF V+LGDD+ I +K P KQL++ ER + I V VP Sbjct: 60 GLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHASTIAVMPVPH 119 Query: 163 ELVSRYGII--EGELIENDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPP 220 + VS YG+I +GE ++ LY ++ VEKP+P++APS++AIIGRY+L PEIF IL P Sbjct: 120 DEVSAYGVIAPQGEG-KDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEIFQILENQAP 178 Query: 221 GRDGEIQLTDALQILLNKNE 240 G EIQLTDA+ LNK + Sbjct: 179 GAGNEIQLTDAID-TLNKTQ 197 >emb|CAC11040.1| (AJ286769) UTP-glucose-1-phosphate uridylyltransferase [Streptococcus pneumoniae] Length = 198 Score = 185 bits (464), Expect = 7e-46 Identities = 102/200 (51%), Positives = 141/200 (70%), Gaps = 9/200 (4%) Query: 47 GIEDILIITGKGKRAIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPL 106 GIEDIL++TGK KR+IED+FD +FELEY LKE+GK + L+ V+E M ++++RQ P Sbjct: 1 GIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGM-RLHFIRQTHPR 59 Query: 107 GLGDAILYAEKHVNGEPFAVLLGDDI--IISKK--PAIKQLIEVAERKNTPVIGVESVPR 162 GLGDA+L A+ V EPF V+LGDD+ I +K P KQL++ +R + I V VP Sbjct: 60 GLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYKRTHASTIAVMPVPH 119 Query: 163 ELVSRYGII--EGELIENDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPP 220 + VS YG+I +GE ++ LY ++ VEKP+P++APS++AIIGRY+L PEIF+IL + P Sbjct: 120 DEVSAYGVIAPQGEG-KDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEIFEILEKQAP 178 Query: 221 GRDGEIQLTDALQILLNKNE 240 G EIQLTDA+ LNK + Sbjct: 179 GAGNEIQLTDAID-TLNKTQ 197 >emb|CAC11035.1| (AJ286764) UTP-glucose-1-phosphate uridylyltransferase [Streptococcus pneumoniae] Length = 198 Score = 184 bits (463), Expect = 9e-46 Identities = 102/200 (51%), Positives = 139/200 (69%), Gaps = 9/200 (4%) Query: 47 GIEDILIITGKGKRAIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPL 106 GIEDIL++TGK KR+IED+FD +FELEY LKE+GK + L V++ +M ++++RQ P Sbjct: 1 GIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLNLVDKTTDM-RLHFIRQTHPR 59 Query: 107 GLGDAILYAEKHVNGEPFAVLLGDDI--IISKK--PAIKQLIEVAERKNTPVIGVESVPR 162 GLGDA+L A+ V EPF V+LGDD+ I +K P KQL++ ER + I V VP Sbjct: 60 GLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHASTIAVMPVPH 119 Query: 163 ELVSRYGII--EGELIENDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPP 220 + VS YG+I +GE ++ LY ++ VEKP+P++APS++AIIGRY+L PEIF IL P Sbjct: 120 DEVSAYGVIAPQGEG-KDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEIFQILENQAP 178 Query: 221 GRDGEIQLTDALQILLNKNE 240 G EIQLTDA+ LNK + Sbjct: 179 GAGNEIQLTDAID-TLNKTQ 197 >emb|CAC11045.1| (AJ286775) UTP-glucose-1-phosphate uridylyltransferase [Streptococcus pneumoniae] Length = 198 Score = 184 bits (463), Expect = 9e-46 Identities = 102/199 (51%), Positives = 136/199 (68%), Gaps = 7/199 (3%) Query: 47 GIEDILIITGKGKRAIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPL 106 GIEDIL++TGK KR+IED+FD +FELEY LKE+GK + L+ V+E M ++++RQ P Sbjct: 1 GIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDEATGM-RLHFIRQTHPR 59 Query: 107 GLGDAILYAEKHVNGEPFAVLLGDDI--IISKK--PAIKQLIEVAERKNTPVIGVESVPR 162 GLGDA+L A+ V EPF V+LGDD+ I +K P KQL+ E+ + I V VP Sbjct: 60 GLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMNDYEKTHASTIAVMPVPH 119 Query: 163 ELVSRYGIIEGELIEND-LYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPG 221 E VS YG+I + D LY ++ VEKP+P+E PS++AIIGRY+L PEIF+IL + PG Sbjct: 120 EDVSSYGVIAPQDEGKDGLYSVETFVEKPAPEETPSDLAIIGRYLLTPEIFEILEKQAPG 179 Query: 222 RDGEIQLTDALQILLNKNE 240 EIQLTDA+ LNK + Sbjct: 180 AGNEIQLTDAID-TLNKTQ 197 >emb|CAC11049.1| (AJ286779) UTP-glucose-1-phosphate uridylyltransferase [Streptococcus pneumoniae] Length = 198 Score = 184 bits (463), Expect = 9e-46 Identities = 102/200 (51%), Positives = 137/200 (68%), Gaps = 9/200 (4%) Query: 47 GIEDILIITGKGKRAIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPL 106 GIEDIL++TGK KR+IED+FD +FELEY LKE+GK + L+ V+E + ++++RQ P Sbjct: 1 GIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKHDLLKLVDETTG-IRLHFIRQSHPR 59 Query: 107 GLGDAILYAEKHVNGEPFAVLLGDDIII----SKKPAIKQLIEVAERKNTPVIGVESVPR 162 GLGDA+L A+ V EPF V+LGDD++ + P KQL+ E + I V VP Sbjct: 60 GLGDAVLQAKAFVANEPFVVMLGDDLMDITDDNAVPLTKQLMNDYESTHASTIAVMPVPH 119 Query: 163 ELVSRYGII--EGELIENDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPP 220 E VS YG+I +GE I N LY ++ VEKP+P++APS++AIIGRY+L PEIF+IL P Sbjct: 120 EEVSAYGVIAPQGEGI-NGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEIFEILENQAP 178 Query: 221 GRDGEIQLTDALQILLNKNE 240 G EIQLTDA+ LNK + Sbjct: 179 GAGNEIQLTDAID-TLNKTQ 197 >emb|CAC11031.1| (AJ286760) UTP-glucose-1-phosphate uridylyltransferase [Streptococcus pneumoniae] >gi|10638147|emb|CAC11032.1| (AJ286761) UTP-glucose-1-phosphate uridylyltransferase [Streptococcus pneumoniae] Length = 198 Score = 183 bits (461), Expect = 1e-45 Identities = 102/200 (51%), Positives = 139/200 (69%), Gaps = 9/200 (4%) Query: 47 GIEDILIITGKGKRAIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPL 106 GIEDIL++TGK KR+IED+FD +FELEY LKE+GK + L+ V+E M ++++RQ P Sbjct: 1 GIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGM-RLHFIRQTHPR 59 Query: 107 GLGDAILYAEKHVNGEPFAVLLGDDI--IISKK--PAIKQLIEVAERKNTPVIGVESVPR 162 GLGDA+L A+ V EPF V+LGDD+ I +K P KQL++ +R + I V VP Sbjct: 60 GLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYKRTHASTIAVMPVPH 119 Query: 163 ELVSRYGII--EGELIENDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPP 220 + VS YG+I +GE ++ LY ++ VEKP+P++APS++AIIGRY+L PEIF IL P Sbjct: 120 DEVSAYGVIAPQGEG-KDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEIFQILENQAP 178 Query: 221 GRDGEIQLTDALQILLNKNE 240 G EIQLTDA+ LNK + Sbjct: 179 GAGNEIQLTDAID-TLNKTQ 197 >emb|CAC11033.1| (AJ286762) UTP-glucose-1-phosphate uridylyltransferase [Streptococcus pneumoniae] Length = 198 Score = 180 bits (453), Expect = 1e-44 Identities = 101/200 (50%), Positives = 138/200 (68%), Gaps = 9/200 (4%) Query: 47 GIEDILIITGKGKRAIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPL 106 GIEDIL++TGK KR+IED+FD +FELEY LKE+GK + L+ V+E M ++++RQ P Sbjct: 1 GIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGM-RLHFIRQTHPR 59 Query: 107 GLGDAILYAEKHVNGEPFAVLLGDDI--IISKK--PAIKQLIEVAERKNTPVIGVESVPR 162 GLGDA+L A+ V EPF V+LGDD+ I +K P KQL++ +R + I V VP Sbjct: 60 GLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYKRTHASTIAVMPVPH 119 Query: 163 ELVSRYGII--EGELIENDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPP 220 + VS YG+I +GE ++ LY ++ VEKP+P++APS++AIIGRY+L PEIF IL Sbjct: 120 DEVSAYGVIAPQGEG-KDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEIFQILENQAS 178 Query: 221 GRDGEIQLTDALQILLNKNE 240 G EIQLTDA+ LNK + Sbjct: 179 GAGNEIQLTDAID-TLNKTQ 197 >pir||D70601 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) galU [similarity] - Mycobacterium tuberculosis (strain H37RV) >gi|2052127|emb|CAB08153.1| (Z94752) galU [Mycobacterium tuberculosis] Length = 306 Score = 173 bits (434), Expect = 2e-42 Identities = 102/287 (35%), Positives = 165/287 (56%), Gaps = 11/287 (3%) Query: 5 AVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIED 64 A++PAAGLGTR LP TK++PKE+LP+VD P I V EA AG E ++I+T +GK + Sbjct: 12 AIVPAAGLGTRFLPATKTVPKELLPVVDTPGIELVAAEAAAAGAERLVIVTSEGKDGVVA 71 Query: 65 YFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHV--NGE 122 +F LE L+ RGK+ L +V ++ + V Q +PLGLG AI E + + + Sbjct: 72 HFVEDLVLEGTLEARGKIAMLAKVRRAPALIKVESVVQAEPLGLGHAIGCVEPTLSPDED 131 Query: 123 PFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLY- 181 AVLL DD+++ ++ + +V + V+ V RE +S YG+ + E + + Y Sbjct: 132 AVAVLLPDDLVL-PTGVLETMSKVRASRGGTVLCAIEVAREEISAYGVFDVEPVPDGDYT 190 Query: 182 ------RIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQIL 235 +++ +VEKP + APS A GRY+L IFD LR G GE+QLTDA+ +L Sbjct: 191 DDPNVLKVRGMVEKPKAETAPSRYAAAGRYVLDRAIFDALRRIDQGAGGEVQLTDAIALL 250 Query: 236 LNKNEILAKRI-EGERYDIGSKFGFVMANLKLSLRREELRNEVLKYL 281 + + + + +G R+D+G+ G++ A + +L R++ ++ ++L Sbjct: 251 IAEGHPVHVVVHQGSRHDLGNPGGYLKAAVDFALDRDDYGPDLRRWL 297 >pir||T45453 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) galU [similarity] - Mycobacterium leprae >gi|4455710|emb|CAB36696.1| (AL035500) putative UTP-glucose-1-phosphate uridylyltransferase [Mycobacterium leprae] Length = 306 Score = 168 bits (422), Expect = 6e-41 Identities = 99/284 (34%), Positives = 163/284 (56%), Gaps = 8/284 (2%) Query: 5 AVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIED 64 A++PAAGLGTR LP TK++PKE+LP+VD P I V EA AG E ++I+T +GK + Sbjct: 15 AIVPAAGLGTRFLPATKTVPKELLPVVDTPGIELVAAEAAAAGAERLVIVTSEGKDGVVA 74 Query: 65 YFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHV--NGE 122 +F + LE L RG L +V E++ + V Q +PLGLG AI AE + + + Sbjct: 75 HFVQDLVLEGTLLARGNKAMLAKVRRAPELIKVESVVQAEPLGLGHAIGCAEPTLAPDED 134 Query: 123 PFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIEN---- 178 +VLL DD+++ ++ + +V + V+ V E +S YG+ + E + Sbjct: 135 AVSVLLPDDLVL-PTGVLETMSKVRASRGGTVLCAIEVASEEISSYGVFDVEPVPGGDNP 193 Query: 179 DLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNK 238 ++ ++ +VEKP ++APS A GRY+L IFD LR G GE+Q+TDA+ +L+ + Sbjct: 194 NVLKVIGMVEKPKAEDAPSTFAAAGRYVLDRAIFDALRRVSRGTGGEVQITDAIALLIKE 253 Query: 239 NEILAKRI-EGERYDIGSKFGFVMANLKLSLRREELRNEVLKYL 281 + + G R+D+G+ G++ A + +L R++ ++ ++L Sbjct: 254 GHPVHVVVHRGSRHDLGNPGGYLKAAVDFALDRDDYGPDLRRWL 297 >gb|AAD50483.1|AF172324_1 (AF172324) GalF [Escherichia coli] Length = 266 Score = 150 bits (376), Expect = 1e-35 Identities = 100/267 (37%), Positives = 149/267 (55%), Gaps = 11/267 (4%) Query: 31 VDRPVIHYVVEEAVKAGIEDILIITGKGKRAIEDYFDRSFELEYYLKERGKLEALREVEE 90 VD+P+I Y+V+E V AGI++IL++T K A+E++FD S+ELE L++R K + L EV+ Sbjct: 1 VDKPMIQYIVDEIVAAGIKEILLVTHASKNAVENHFDTSYELESLLEQRVKRQLLAEVQS 60 Query: 91 I-GEMVDIYYVRQKKPLGLGDAILYAEKHVNGEPFAVLLGDDII--ISKKPAIKQLIEVA 147 I V I VRQ +PLGLG +IL A + PF V+L D +I S P L + Sbjct: 61 ICPPGVTIMNVRQGEPLGLGHSILCARPAIGDNPFVVVLPDVVIDDASADPLRYNLAAMI 120 Query: 148 ERKN---TPVIGVESVPRELVSRYGIIEGEL---IENDLYRIKRLVEKP-SPKEAPSNIA 200 R N + + +P +L S Y +I+ + E + RI +EKP P+ S+I Sbjct: 121 ARFNETGRSQVLAKRMPGDL-SEYSVIQTKEPLDREGKVSRIVEFIEKPDQPQTLDSDIM 179 Query: 201 IIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNEILAKRIEGERYDIGSKFGFV 260 +GRY+L +I+ L T PG G IQLTDA+ L K + A + G+ YD G K G++ Sbjct: 180 AVGRYVLSADIWPELERTQPGAWGRIQLTDAIAELAKKQSVDAMLMTGDSYDCGKKMGYM 239 Query: 261 MANLKLSLRREELRNEVLKYLKSILKE 287 A +K LR + + K ++ +L E Sbjct: 240 QAFVKYGLRNLKEGAKFRKGIEKLLSE 266 >gb|AAB49385.1| (M84642) putative glucose-1-phosphate uridylyltransferase [Salmonella enterica] Length = 251 Score = 128 bits (319), Expect = 7e-29 Identities = 91/251 (36%), Positives = 136/251 (53%), Gaps = 9/251 (3%) Query: 46 AGIEDILIITGKGKRAIEDYFDRSFELEYYLKERGKLEALREVEEIGEM-VDIYYVRQKK 104 AGI++I+++T K A+E++FD S+ELE L++R K + L EV+ I V I VRQ + Sbjct: 1 AGIKEIVLVTHASKNAVENHFDTSYELESLLEQRVKRQLLAEVQSICPPGVTIMNVRQAQ 60 Query: 105 PLGLGDAILYAEKHVNGEPFAVLLGDDII--ISKKPAIKQLIEVAERKNTPVIGVESVPR 162 PLGLG +IL A V PF V+L D II + P L + R N R Sbjct: 61 PLGLGHSILCARPVVGDNPFIVVLPDIIIDDATADPLRYNLAAMVARFNETGRSQVLAKR 120 Query: 163 EL--VSRYGIIEG-ELIEND--LYRIKRLVEKPS-PKEAPSNIAIIGRYILIPEIFDILR 216 +S Y +I+ E ++N+ + RI +EKP P+ S++ +GRY+L +I+ L Sbjct: 121 MKGDLSEYSVIQTKEPLDNEGKVSRIVEFIEKPDQPQTLDSDLMAVGRYVLSADIWAELE 180 Query: 217 ETPPGRDGEIQLTDALQILLNKNEILAKRIEGERYDIGSKFGFVMANLKLSLRREELRNE 276 T PG G IQLTDA+ L K + A + G+ YD G K G++ A +K LR + + Sbjct: 181 RTEPGAWGRIQLTDAIAELAKKQSVDAMLMTGDSYDCGKKMGYMQAFVKYGLRNLKEGAK 240 Query: 277 VLKYLKSILKE 287 K ++ +L E Sbjct: 241 FRKSIEQLLHE 251 >pir||A75596 probable glucose-1-phosphate thymidylyltransferase - Deinococcus radiodurans (strain R1) >gi|6460571|gb|AAF12277.1|AE001862_103 (AE001862) glucose-1-phosphate thymidylyltransferase, putative [Deinococcus radiodurans] Length = 361 Score = 120 bits (297), Expect = 3e-26 Identities = 85/264 (32%), Positives = 137/264 (51%), Gaps = 34/264 (12%) Query: 1 MIRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKR 60 + KA+IPAAGLGTR+ P+T + PK +L + +P+I + + +AGI DI I+ R Sbjct: 8 LFMKALIPAAGLGTRLRPLTFTRPKPVLRVAGQPIIRHAIRTLTEAGITDIGIVVSDVTR 67 Query: 61 AIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVN 120 E+++ A+RE+ + V + + Q LGLG A+L A + V Sbjct: 68 D---------EIQH---------AVREIRD----VKLTLINQHDQLGLGHAVLTAREWVG 105 Query: 121 GEPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDL 180 + F V LGD++ + + IE +K+ P + V + +G+ E D Sbjct: 106 QDDFCVYLGDNLF---EFGARPFIESFHQKH-PAALIALVKVADPTAFGV-----AELDG 156 Query: 181 YRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNE 240 +I RLVEK PK+ PSN+A+ G Y P+IF++L PP GE ++TD +Q L+ + + Sbjct: 157 EQITRLVEK--PKDPPSNLAVAGLYCFTPQIFEVLDVMPPSARGEYEITDGIQGLIERGQ 214 Query: 241 -ILAKRIEGERYDIGSKFGFVMAN 263 ++ +R+EG D G + AN Sbjct: 215 TVVGQRVEGWWKDTGRPADLLDAN 238 >pir||T48866 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) [validated] - Streptomyces argillaceus >gi|1814004|emb|CAA71846.1| (Y10907) TDP-D-Glucose synthase [Streptomyces argillaceus] >gi|3334819|emb|CAA07754.1| (AJ007932) dTDP-glucose synthase [Streptomyces argillaceus] Length = 355 Score = 114 bits (283), Expect = 1e-24 Identities = 78/264 (29%), Positives = 141/264 (52%), Gaps = 38/264 (14%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 KA++ + G GTR+ PIT + PK+++P+ ++PV+ Y +E+ +AGI D+ I+ G+ R IE Sbjct: 2 KALVLSGGSGTRLRPITHTSPKQLVPVANKPVLFYALEDIAQAGITDVGIVVGETAREIE 61 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 D A+ + + G + + Y+ Q+KPLGL A+L A ++ + Sbjct: 62 D-------------------AVGDGSKFG--LQVTYLPQEKPLGLAHAVLIARDYLGDDD 100 Query: 124 FAVLLGDDIIISKKPAIKQLIEV--AERKNTPVIGVESVPRELVSRYGIIEGELIENDLY 181 F + LGD+ ++ I L++ A+R + ++ + VP ++GE Sbjct: 101 FVMYLGDNFVVG---GIAGLVDEFRADRPDARIL-LTPVPDPTAFGIAELDGE------G 150 Query: 182 RIKRLVEKPS-PKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILL-NKN 239 R+ RL EKP+ PK S++A+IG Y+ P + + +R P GE+++T A+Q L+ N++ Sbjct: 151 RVVRLEEKPTHPK---SDMAVIGVYLFTPLVHEAVRAIEPSWRGELEITHAIQWLIDNRH 207 Query: 240 EILAKRIEGERYDIGSKFGFVMAN 263 ++ + I G D G+ + N Sbjct: 208 DVRSTVIHGYWKDTGNVMDMLEVN 231 >pir||A69079 glucose-1-phosphate thymidylyltransferase homolog - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622712|gb|AAB86062.1| (AE000918) glucose-1-phosphate thymidylyltransferase homolog [Methanobacterium thermoautotrophicum] Length = 423 Score = 113 bits (281), Expect = 2e-24 Identities = 82/266 (30%), Positives = 137/266 (50%), Gaps = 35/266 (13%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 +AVI AG GTRM P+T + PK MLP+ +P++ Y V+ G+ DI++ITG + A+ Sbjct: 2 QAVILTAGEGTRMRPLTLTRPKTMLPVAGKPILQYSVDALRDNGVHDIVMITGYHEEAVR 61 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 +F + G V+I YVRQ++ LG AI A + ++ E Sbjct: 62 SHFG---------------------DGSGSGVNITYVRQEERLGTAHAIGQASELIDDE- 99 Query: 124 FAVLLGDDIIISKKPAIKQLI-EVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLYR 182 F VL GD II+ + LI ERK ++ + VP S +G+++ +E D R Sbjct: 100 FIVLNGD--IITDPGLMGDLIGSYHERKPETLMVLREVPDP--SSFGVVK---VEGD--R 150 Query: 183 IKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNEIL 242 ++ ++EKP P N+ G Y+ P +FD + TP R GE ++TD + + + ++++ Sbjct: 151 VREIIEKPGPDAGAGNLINTGIYVFSPAVFDYIERTPLSRRGEYEITDTIMMQV-RDDLP 209 Query: 243 AKRIEGER--YDIGSKFGFVMANLKL 266 + I +R D+G + + A+ +L Sbjct: 210 VRAIISDRDWIDVGRPWELLEASERL 235 >pir||A75098 glucose-1-phosphate thymidylyltransferase (grad-3) PAB0784 - Pyrococcus abyssi (strain Orsay) >gi|5458598|emb|CAB50086.1| (AJ248286) glucose-1-phosphate thymidylyltransferase (graD-3) [Pyrococcus abyssi] Length = 352 Score = 113 bits (279), Expect = 3e-24 Identities = 78/275 (28%), Positives = 138/275 (49%), Gaps = 35/275 (12%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 KA+I + G GTR+ P+T S K+++P+ ++PV+ Y +E+ ++AGI +I II G K Sbjct: 2 KALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKE--- 58 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 + + V+ + +I ++ Q +P GL AIL A ++ + Sbjct: 59 -------------------QVIETVKSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDD 99 Query: 124 FAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLYRI 183 F + LGD+I+ K+ E ++ + ++ P++ +G+ E + D I Sbjct: 100 FVMYLGDNILREGIVRHKEHFEKSDYDASILLCEVPNPQQ----FGVAE---LSEDGKTI 152 Query: 184 KRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILL-NKNEIL 242 KRL+EK PK PSN+A++G Y P I + +R P E+++TDA+Q L+ N ++ Sbjct: 153 KRLIEK--PKHPPSNLALVGIYFFRPIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVG 210 Query: 243 AKRIEGERYDIGSKFGFVMANLKLSLRREELRNEV 277 ++ G D G + AN L +E+ E+ Sbjct: 211 WTKVTGWWKDTGKPEDLLEAN---RLVLDEIEREI 242 >gb|AAK41110.1| UTP-glucose-1-phosphate uridylyltransferase [Sulfolobus solfataricus] Length = 246 Score = 111 bits (276), Expect = 7e-24 Identities = 79/260 (30%), Positives = 135/260 (51%), Gaps = 35/260 (13%) Query: 12 LGTRMLPITKSMPKEMLPIVD----RPVIHYVVEEAVKAGIEDILIITGKGKRAIEDYFD 67 +GTR+LP +K +PKEM PI +P+I + E+ GI D +I+ G+GKR IED+F Sbjct: 1 MGTRLLPASKEIPKEMFPIPFNGQFKPIIQIIFEQLYDIGIRDFVIVVGRGKRVIEDHFT 60 Query: 68 RSFELEYYLKERGKL---EALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEPF 124 ++ YL+ +GK+ LR+ + E I +V Q +P G GDA+L AE + GE Sbjct: 61 PDYDFINYLEAKGKVIQANYLRQFYQKVENSRIAFVNQPEPKGFGDAVLRAEPFIQGE-- 118 Query: 125 AVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGII----EGELIENDL 180 +++ D I+ P ++ N+ ++ PR YG++ +G +I+ Sbjct: 119 FLVVAADTILPMIPISSMVV------NSFLVTTVQDPRP----YGVVLVDKQGCVID--- 165 Query: 181 YRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNE 240 + EK PK+ SN+ ++ Y+ EIFD LR+ + E+QLTD ++ L+ + Sbjct: 166 -----IEEK--PKQPKSNLVVVPYYMFDEEIFDELRQIK--YEEELQLTDGIKGLIKRGR 216 Query: 241 ILAKRIEGERYDIGSKFGFV 260 + + YD+G+ ++ Sbjct: 217 RFKAIMVDKVYDLGTVENYI 236 >emb|CAB57491.1| (Y18930) UDP-glucose pyrophosphorylase [Sulfolobus solfataricus] Length = 246 Score = 111 bits (276), Expect = 7e-24 Identities = 79/260 (30%), Positives = 135/260 (51%), Gaps = 35/260 (13%) Query: 12 LGTRMLPITKSMPKEMLPIVD----RPVIHYVVEEAVKAGIEDILIITGKGKRAIEDYFD 67 +GTR+LP +K +PKEM PI +P+I + E+ GI D +I+ G+GKR IED+F Sbjct: 1 MGTRLLPASKEIPKEMFPIPFNGQFKPIIQIIFEQLYDIGIRDFVIVVGRGKRVIEDHFT 60 Query: 68 RSFELEYYLKERGKL---EALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEPF 124 ++ YL+ +GK+ LR+ + E I +V Q +P G GDA+L AE + GE Sbjct: 61 PDYDFINYLEAKGKVIQANYLRQFYQKVENSRIAFVNQPEPKGFGDAVLRAEPFIQGE-- 118 Query: 125 AVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGII----EGELIENDL 180 +++ D I+ P ++ N+ ++ PR YG++ +G +I+ Sbjct: 119 FLVVAADTILPMIPISSMVV------NSFLVTTVQDPRP----YGVVLVDKQGCVID--- 165 Query: 181 YRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNE 240 + EK PK+ SN+ ++ Y+ EIFD LR+ + E+QLTD ++ L+ + Sbjct: 166 -----IEEK--PKQPKSNLVVVPYYMFDEEIFDELRQIK--YEEELQLTDGIKGLIKRGR 216 Query: 241 ILAKRIEGERYDIGSKFGFV 260 + + YD+G+ ++ Sbjct: 217 RFKAIMVDKVYDLGTVENYI 236 >gi|11497938 glucose-1-phosphate thymidylyltransferase (graD-2) [Archaeoglobus fulgidus] >gi|7448159|pir||E69290 glucose-1-phosphate thymidylyltransferase (graD-2) homolog - Archaeoglobus fulgidus >gi|2650311|gb|AAB90910.1| (AE001082) glucose-1-phosphate thymidylyltransferase (graD-2) [Archaeoglobus fulgidus] Length = 352 Score = 111 bits (274), Expect = 1e-23 Identities = 79/280 (28%), Positives = 138/280 (49%), Gaps = 38/280 (13%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKG-KRAI 62 K V+ G GTR+ P+T + PK+++P+ ++PV Y +E+ + AGI+++ II G+ + Sbjct: 2 KGVLLHGGAGTRLRPLTFTGPKQLIPVANKPVSQYCLEDMIGAGIKEVAIILGETYPEMV 61 Query: 63 EDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGE 122 E+++ I Y+ Q KPLG+ A+ A+ V E Sbjct: 62 EEHYGDGSRFG---------------------CKITYIHQGKPLGIAHAVYLAKDFVGDE 100 Query: 123 PFAVLLGDDIIISKKPAIKQLIEVAERKN-TPVIGVESVPRELVSRYGIIEGELIENDLY 181 F V LGD++I + IK+ ++ + ++ I ++ V EGE Sbjct: 101 KFVVYLGDNLI---QDGIKEYVKRFDEEDFDAFILLKEVEDPRAFGVAKFEGE------- 150 Query: 182 RIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILL-NKNE 240 R+ L+EK PKE PSN A+IG Y+ P +FDI+++ P GE+++TD LQ ++ N Sbjct: 151 RLVGLIEK--PKEPPSNYAVIGVYMFKPVVFDIIKDLKPSWRGELEITDTLQKMIENGYN 208 Query: 241 ILAKRIEGERYDIGSKFGFVMANLKL--SLRREELRNEVL 278 + +++G +D G + N + + ++ EVL Sbjct: 209 VGYAKLKGWWFDTGKAEDILKVNATILDERAKRSVKGEVL 248 >gb|AAG19459.1| (AE005038) glucose-1-phosphate thymidylyltransferase; GraD4 [Halobacterium sp. NRC-1] Length = 240 Score = 111 bits (274), Expect = 1e-23 Identities = 79/252 (31%), Positives = 123/252 (48%), Gaps = 32/252 (12%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 +AV+ AAG GTR+ P+T+ PK M+ I +P++ + E+ V G E I+ I G K+ I Sbjct: 2 QAVVLAAGEGTRLRPLTEDKPKGMVEIAGKPILTHCFEQLVALGAEKIVAIVGYRKQNII 61 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 ++ F + V I Y Q++ GL A+L AE+HVN E Sbjct: 62 SHYGDEF----------------------DGVPITYAHQREQNGLAHALLKAEEHVN-ED 98 Query: 124 FAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLYRI 183 F ++LGD+I + + + E + VE V + SRYG+ + ND I Sbjct: 99 FMLMLGDNIFRANLEDV--VNRQQEERADAAFLVEEVDWDEASRYGVCD----TNDYGEI 152 Query: 184 KRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNEIL- 242 + +VEKP + PSN+ + G Y P IF + P E +L+DA+ +L+ + Sbjct: 153 QEVVEKPD--DPPSNLVMTGFYTFSPAIFQACKLVQPSDRAEYELSDAIDLLIKSGRTID 210 Query: 243 AKRIEGERYDIG 254 A +EG R D+G Sbjct: 211 AIPMEGWRIDVG 222 >pir||F71151 probable glucose-1-phosphate thymidylyltransferase - Pyrococcus horikoshii >gi|3256816|dbj|BAA29499.1| (AP000002) 356aa long hypothetical glucose-1-phosphate thymidylyltransferase [Pyrococcus horikoshii] Length = 356 Score = 110 bits (272), Expect = 2e-23 Identities = 79/275 (28%), Positives = 137/275 (49%), Gaps = 35/275 (12%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 KA+I + G GTR+ P+T S K+++P+ ++PV+ Y +E+ ++AGI +I I+ G ++ Sbjct: 6 KALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIVVGPNADLVK 65 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 + V + +I ++ Q +P GL AIL A ++ E Sbjct: 66 ----------------------KTVMSVDWDANIEFIYQGEPKGLAHAILVARDYLGDED 103 Query: 124 FAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLYRI 183 F + LGD+I+ K+ E ++ + ++ P++ +G+ E + D I Sbjct: 104 FVMYLGDNILREGIVRHKEHFEKSDYDASILLCEVPNPQQ----FGVAE---LSEDGKTI 156 Query: 184 KRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILL-NKNEIL 242 KRLVEK PK PSN+A++G Y P I + +R P E+++TDA+Q L+ N ++ Sbjct: 157 KRLVEK--PKHPPSNLALVGIYFFRPIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVG 214 Query: 243 AKRIEGERYDIGSKFGFVMANLKLSLRREELRNEV 277 ++ G D G + AN L +E+ EV Sbjct: 215 WTKVTGWWKDTGKPEDLLEAN---RLVLDEIEKEV 246 >gb|AAA67589.1| (M87049) similar to Streptomyces griseus StrD protein [Escherichia coli] Length = 292 Score = 109 bits (270), Expect = 4e-23 Identities = 77/238 (32%), Positives = 119/238 (49%), Gaps = 30/238 (12%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 K ++ A G GTR+ PIT+ + K++LPI D+P+I+Y + + AGI +ILIIT + Sbjct: 2 KGIMLAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKG-- 59 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 YF R L +V E G + + Y Q P GL A + E +NGEP Sbjct: 60 -YFQR---------------LLGDVGEFG--IQLEYAEQPSPDGLAQAFIIGETFLNGEP 101 Query: 124 FAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLYRI 183 ++LGD+I + + K L VA R PV G + + E R+G +E + D +R Sbjct: 102 SCLVLGDNIFFGQGFSPK-LRHVAARTEGPVFGYQVMDPE---RFGXVEFD----DNFRA 153 Query: 184 KRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNEI 241 L EK PK+ SN A+ G Y ++ + ++ P GE+++T Q+ L + Sbjct: 154 ISLEEK--PKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNL 209 >pir||S30683 hypothetical protein o292 - Escherichia coli Length = 292 Score = 106 bits (263), Expect = 2e-22 Identities = 76/238 (31%), Positives = 118/238 (48%), Gaps = 30/238 (12%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 K ++ A G GTR+ PIT+ + K++LPI D+P+I+Y + + AGI +ILIIT + Sbjct: 2 KGIMLAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKG-- 59 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 YF R L +V E G + + Y Q P GL A + E +NGEP Sbjct: 60 -YFQR---------------LLGDVGEFG--IQLEYAEQPSPDGLAQAFIIGETFLNGEP 101 Query: 124 FAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLYRI 183 ++LGD+I + + K L VA R PV G + + E R+ +E + D +R Sbjct: 102 SCLVLGDNIFFGQGFSPK-LRHVAARTEGPVFGYQVMDPE---RFXXVEFD----DNFRA 153 Query: 184 KRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNEI 241 L EK PK+ SN A+ G Y ++ + ++ P GE+++T Q+ L + Sbjct: 154 ISLEEK--PKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNL 209 >pir||G72325 glucose-1-phosphate thymidylyltransferase - Thermotoga maritima (strain MSB8) >gi|4981396|gb|AAD35944.1|AE001752_11 (AE001752) glucose-1-phosphate thymidylyltransferase [Thermotoga maritima] Length = 355 Score = 105 bits (260), Expect = 6e-22 Identities = 76/280 (27%), Positives = 141/280 (50%), Gaps = 37/280 (13%) Query: 2 IRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRA 61 ++KA++ AG GTR+ P+T + K ++PI ++P++ Y +E +AGIE++ I+ Sbjct: 1 MKKAIVLCAGKGTRLRPLTFTTAKHLIPIANKPILFYSLENIARAGIEEVGIVVSP---- 56 Query: 62 IEDYFDRSFELEYYLKERGKLEALREVEEIGEM--VDIYYVRQKKPLGLGDAILYAEKHV 119 E + + GE + I Y+ Q++P GL A+ + + + Sbjct: 57 ------------------HNAEEFKSIVGTGENFGLRISYIIQEEPKGLAHAVWVSREFL 98 Query: 120 NGEPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIEND 179 E F + LGD++I+ + E ++ + ++ P +R+G+ ++E D Sbjct: 99 GDEDFMMYLGDNLILEDLGKFVKDFENSDYAASILLSPVKDP----TRFGV---AVMEGD 151 Query: 180 LYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKN 239 R+ ++VEK PK PSN+AI+G Y+ +IF+ ++ P GE+++TDA++ L+ K Sbjct: 152 --RVIKVVEK--PKTPPSNLAIVGLYLFRNKIFEGIKNIKPSWRGELEITDAIEYLIEKG 207 Query: 240 E-ILAKRIEGERYDIGSKFGFVMANLKLSLR-REELRNEV 277 E + + G D G + AN K+ + EEL E+ Sbjct: 208 EKVRGYIVYGWWKDTGKPEDLLEANRKILMETTEELLGEM 247 >pir||S76366 hypothetical protein - Synechocystis sp. (strain PCC 6803) >gi|1001590|dbj|BAA10218.1| (D64000) glucose-1-phosphate thymidylyltransferase [Synechocystis sp.] Length = 393 Score = 104 bits (257), Expect = 1e-21 Identities = 77/272 (28%), Positives = 127/272 (46%), Gaps = 53/272 (19%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 KA+I + G GTR+ P+T + K+++P+ ++P++ Y +E KAGI DI II Sbjct: 30 KALILSGGKGTRLRPLTYTGAKQLVPVANKPILWYGIEAIAKAGITDIGIIIS------- 82 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEM--VDIYYVRQKKPLGLGDAILYAEKHVNG 121 E G E ++ + GE + I Y+ Q +PLGL A+ A + Sbjct: 83 -------------PETG--EEIKTITGNGEKFGIQITYILQSEPLGLAHAVKTAADFLQD 127 Query: 122 EPFAVLLGDDIIIS---------KKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIE 172 PF + LGD++I + ++ LI + N GV +V Sbjct: 128 SPFVMYLGDNLIQDHLEQFLAHFQAKSLDSLILLRRVSNPSAFGVATV------------ 175 Query: 173 GELIENDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDAL 232 ND ++ LVEK P+ PSN+A++G Y P I + P GE+++TDA+ Sbjct: 176 -----NDQGKVLALVEK--PEHPPSNLALVGLYFFAPTIHQAIANIEPSARGELEITDAI 228 Query: 233 QILLNKN-EILAKRIEGERYDIGSKFGFVMAN 263 Q L++ + + + +++G D G K + AN Sbjct: 229 QYLISHDYRVESLQLKGWWLDTGKKDDLLAAN 260 >sp|P39629|SPSI_BACSU SPORE COAT POLYSACCHARIDE BIOSYNTHESIS PROTEIN SPSI >gi|2126974|pir||S39726 spore coat polysaccharide synthesis spsI - Bacillus subtilis >gi|580880|emb|CAA51627.1| (X73124) ipa-71d [Bacillus subtilis] >gi|2636319|emb|CAB15810.1| (Z99123) alternate gene name: ipa-71d [Bacillus subtilis] Length = 246 Score = 104 bits (256), Expect = 2e-21 Identities = 73/262 (27%), Positives = 138/262 (51%), Gaps = 33/262 (12%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 K VI A G G+R++P+TK++ K +LP+ P+I++ + + +AGI+DIL+I+ K Sbjct: 2 KGVILAGGNGSRLMPLTKAVNKHLLPVGPYPMIYWSIMKLQEAGIKDILLISQK------ 55 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 ++ + ++L L EE+G V I Y Q G+ D + YA++ E Sbjct: 56 EHMPQFYKL------------LGNGEELG--VTITYQVQPAASGISDGLSYAKRFTKKES 101 Query: 124 FAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPREL--VSRYGIIEGELIENDLY 181 F +LLGD+I + ++K E E++ G + + +E+ R+GI E I+ Sbjct: 102 FILLLGDNIF---EDSLKPYTERFEQQGK---GAKVLLKEVDDPERFGIAE---IDEKNK 152 Query: 182 RIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNEI 241 RI+ ++EK P++ P+N+ + G Y+ E+F + + P + GE+++TD + + +++ Sbjct: 153 RIRSIIEK--PEQPPTNLCVTGIYMYDAEVFSYIEQISPSKRGELEITDVNNLYIENSQL 210 Query: 242 LAKRIEGERYDIGSKFGFVMAN 263 + G D G+ +A+ Sbjct: 211 TYDVLSGWWVDAGTHESLYLAS 232 >gb|AAG18650.1| (AE004970) glucose-1-phosphate thymidylyltransferase; GraD5 [Halobacterium sp. NRC-1] Length = 395 Score = 103 bits (255), Expect = 2e-21 Identities = 74/263 (28%), Positives = 124/263 (47%), Gaps = 33/263 (12%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 +AV+ AAG G R+ P+T++ PK M+P+ ++P++ ++V+ V AG+ ++++ G + ++ Sbjct: 2 QAVVLAAGKGERLWPLTENRPKPMVPVANQPILEHIVDALVSAGVTRVMLVVGSNRERVQ 61 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 +F+ ++I YV Q + LG G A+ AE V GE Sbjct: 62 RHFEDGSRWG---------------------IEISYVVQDRQLGTGHALAQAESVV-GES 99 Query: 124 FAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLYRI 183 F L GD +I + ++ + E +GV V E S YG+++ D + Sbjct: 100 FVALNGDRVIDAS--LVEDVWECHRESGDSAMGVTQV--ETPSAYGVVD-----LDGGTV 150 Query: 184 KRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNEILA 243 + E+P P+ S G Y P +F +R T GE+ LTDAL L +E+ A Sbjct: 151 TDIDEQPVPELVASEYINAGVYAFGPSVFAAIRRTDSY--GELALTDALDEQLADHELRA 208 Query: 244 KRIEGERYDIGSKFGFVMANLKL 266 R +G D+ + V AN L Sbjct: 209 VRYDGRWLDVSEPWDLVAANSAL 231 >gb|AAK41126.1| Sugar phosphate nucleotydyl transferase [Sulfolobus solfataricus] Length = 344 Score = 103 bits (254), Expect = 3e-21 Identities = 89/280 (31%), Positives = 141/280 (49%), Gaps = 49/280 (17%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGK--RA 61 +AVI G GTR+ P+T + PK+++ + +PV +V+E+ AGI D++I+ G R Sbjct: 2 EAVILHGGQGTRLRPLTHTGPKQLIKVAGKPVSQWVLEQIRDAGIRDVIIVLGDNAPTRV 61 Query: 62 IEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNG 121 +E Y D S + G V I YV Q K GL DA+ Y K V Sbjct: 62 VEYYGDGS--------------------KFG--VRITYVYQGKARGLADAV-YKVKDVVS 98 Query: 122 EPFAVLLGDDII---ISKKPAIKQLIEVAERK-NTPVIGVESVPRELVSRYGIIEGELIE 177 + F V LGD+++ +SK + K + K N P +R+G+ +I+ Sbjct: 99 DKFLVYLGDNLVPYDLSKFSSFKGSASILLAKVNNP------------NRFGVA---VIK 143 Query: 178 NDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLN 237 + R+ +L+EKP KE S++A++G Y EIFD++ P GE+++TDA+Q L++ Sbjct: 144 DG--RVVKLIEKP--KEQISDLALVGVYGFTREIFDVIESLKPSWRGELEITDAIQGLID 199 Query: 238 K-NEILAKRIEGERYDIGSKFGFVMANLKLSLRREELRNE 276 + E+ + I+G D G+ + AN L R E R E Sbjct: 200 RGREVNYEIIQGWWKDTGTPKDILEANAFLLDRYAESRIE 239 >emb|CAB57473.1| (Y18930) glucose-1-phosphate thymidylyltransferase (graD-2) [Sulfolobus solfataricus] Length = 344 Score = 103 bits (254), Expect = 3e-21 Identities = 89/280 (31%), Positives = 141/280 (49%), Gaps = 49/280 (17%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGK--RA 61 +AVI G GTR+ P+T + PK+++ + +PV +V+E+ AGI D++I+ G R Sbjct: 2 EAVILHGGQGTRLRPLTHTGPKQLIKVAGKPVSQWVLEQIRDAGIRDVIIVLGDNAPTRV 61 Query: 62 IEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNG 121 +E Y D S + G V I YV Q K GL DA+ Y K V Sbjct: 62 VEYYGDGS--------------------KFG--VRITYVYQGKARGLADAV-YKVKDVVS 98 Query: 122 EPFAVLLGDDII---ISKKPAIKQLIEVAERK-NTPVIGVESVPRELVSRYGIIEGELIE 177 + F V LGD+++ +SK + K + K N P +R+G+ +I+ Sbjct: 99 DKFLVYLGDNLVPYDLSKFSSFKGSASILLAKVNNP------------NRFGVA---VIK 143 Query: 178 NDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLN 237 + R+ +L+EKP KE S++A++G Y EIFD++ P GE+++TDA+Q L++ Sbjct: 144 DG--RVVKLIEKP--KEQISDLALVGVYGFTREIFDVIESLKPSWRGELEITDAIQGLID 199 Query: 238 K-NEILAKRIEGERYDIGSKFGFVMANLKLSLRREELRNE 276 + E+ + I+G D G+ + AN L R E R E Sbjct: 200 RGREVNYEIIQGWWKDTGTPKDILEANAFLLDRYAESRIE 239 >pir||T46521 probable dTDP-1-glucose synthase [imported] - Streptomyces violaceoruber >gi|4218548|emb|CAA09637.1| (AJ011500) putative dTDP-1-glucose synthase [Streptomyces violaceoruber] Length = 353 Score = 102 bits (253), Expect = 4e-21 Identities = 68/253 (26%), Positives = 124/253 (48%), Gaps = 32/253 (12%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 KA+I + G+GTR+ P T SMPK+++P+ ++P++ + +E G+E++ ++ G Sbjct: 2 KALILSGGMGTRLRPFTYSMPKQLVPVANKPILVHCLENVRAIGVEEVAVVVG------- 54 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 DR+ E+ + + +D+ Y++Q+ PLGL + AE+ + E Sbjct: 55 ---DRADEVRAVVGDGSAFG-----------LDVTYLQQEAPLGLAHCVSIAEEFLGDED 100 Query: 124 FAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLYRI 183 F + LGD+I+ + ++ + PR YG+ E + R+ Sbjct: 101 FVMYLGDNILAEGIAESARAFRDERSAARLLLTKVADPR----AYGVAETDATG----RV 152 Query: 184 KRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNE-IL 242 LVEK P+ S++A+IG Y + D +R P GE+++TDA+Q L+ + + ++ Sbjct: 153 HALVEK--PERPRSDLAVIGVYFFTAAVHDAVRAIEPSARGELEITDAIQYLVERGDRVV 210 Query: 243 AKRIEGERYDIGS 255 A G D GS Sbjct: 211 ADEYTGYWKDTGS 223 >gb|AAK41974.1| Sugar phosphate nucleotydyl transferase [Sulfolobus solfataricus] Length = 344 Score = 101 bits (249), Expect = 1e-20 Identities = 87/276 (31%), Positives = 141/276 (50%), Gaps = 41/276 (14%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGK--RA 61 +AVI G GTR+ P+T + PK+++ + +P+ +V+E+ +GI+DIL+I G R Sbjct: 2 EAVILHGGQGTRLRPLTHTGPKQLIKVAGKPISQWVLEQIRDSGIKDILLILGDNTPTRV 61 Query: 62 IEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNG 121 ++ Y D S + G V+I YV Q K GL DA+ Y K + Sbjct: 62 VDYYGDGS--------------------KFG--VNITYVYQGKARGLADAV-YRVKDLVS 98 Query: 122 EPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLY 181 E F V LGD+++ L + K + I + V +R+G+ + EN Sbjct: 99 EKFLVYLGDNLVFY------DLRKFLSFKGSASILLAKVDNP--NRFGV--AVINEN--- 145 Query: 182 RIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNK-NE 240 ++ RLVEKP KE S++A++G Y EIF+++ + P GE+++TDA+Q L+N+ E Sbjct: 146 KVIRLVEKP--KEKISDLALVGVYGFTDEIFEVIEKLKPSWRGELEITDAIQGLINEGKE 203 Query: 241 ILAKRIEGERYDIGSKFGFVMANLKLSLRREELRNE 276 + + I+G D G+ + AN L R E + E Sbjct: 204 VNYEIIQGWWKDTGTPKDILEANSFLLDRYAERKIE 239 >gb|AAD12972.1| (AF078135) RmlA [Leptospira borgpetersenii] Length = 294 Score = 100 bits (247), Expect = 2e-20 Identities = 79/249 (31%), Positives = 123/249 (48%), Gaps = 30/249 (12%) Query: 3 RKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAI 62 RK +I A G GTR+ P+T + K++LP+ D+P+I+Y + + AGI++IL+I+ +A Sbjct: 4 RKGIILAGGSGTRLYPVTYVVSKQLLPVYDKPMIYYPLTTLMLAGIKEILLIS--TPQAT 61 Query: 63 EDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGE 122 Y E L + ++ G + I Y Q +P GL A E VNG Sbjct: 62 PMY----------------KELLGDGKQWG--ISIEYAVQPEPGGLAQAYWIGENFVNGH 103 Query: 123 PFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLYR 182 P ++LGD+I A+ L+E A +K T V + P RYG++E + R Sbjct: 104 PSVLILGDNIYFGHNLAV--LLENASKK-TKGSTVFAYPVHDPERYGVVEFD----SERR 156 Query: 183 IKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNEIL 242 + EKPS + SN A+ G Y E+ I + P GE+++TD +I L + IL Sbjct: 157 AVSIEEKPS--KPKSNYAVTGLYFYDEEVVSIAKSIKPSARGELEITDVNRIYLERG-IL 213 Query: 243 AKRIEGERY 251 ++ G Y Sbjct: 214 NVQVMGRGY 222 >gb|AAB50923.1| (L47163) glucose-1-phosphate thymidylyltransferase [Streptomyces peucetius] >gi|1588468|prf||2208414A glucose phosphate thymidylate transferase [Streptomyces peucetius] Length = 351 Score = 100 bits (247), Expect = 2e-20 Identities = 69/235 (29%), Positives = 122/235 (51%), Gaps = 33/235 (14%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 KA++ + G GTR+ P T + PK+++P+ ++PV++YV+E+ +A I ++ I+ G+ I Sbjct: 2 KALVLSGGSGTRLRPFTHTSPKQLVPVANKPVLYYVLEDIAQASITEVGIVVGETSNEIR 61 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 +A+ + G + + Y+ Q+ PLGL A+L A ++ E Sbjct: 62 -------------------KAVGSGDRFG--LRVTYLPQEAPLGLAHAVLIARDYLGEED 100 Query: 124 FAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVE-SVPRELVSRYGIIEGELIENDLYR 182 F + LGD+ ++ AER + ++ S P S +G+ E I D R Sbjct: 101 FVMYLGDNFVVGGIAGNSSTFR-AERPDAQILLTRVSDP----SSFGVAE---IGCD-GR 151 Query: 183 IKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLN 237 + L EK P+ S++A++G Y+ P + + +R P R GE+++TDALQ LL+ Sbjct: 152 VVALEEK--PRHPRSDLAVVGIYLFTPVVHEAVRALTPSRRGELEITDALQWLLD 204 >sp|P55257|RFBA_YEREN GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (DTDP-GLUCOSE SYNTHASE) (DTDP-GLUCOSE PYROPHOSPHORYLASE) >gi|479759|pir||S35294 probable glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) - Yersinia enterocolitica >gi|48585|emb|CAA79347.1| (Z18920) WbbS [Yersinia enterocolitica] Length = 289 Score = 99.8 bits (245), Expect = 3e-20 Identities = 74/239 (30%), Positives = 124/239 (50%), Gaps = 31/239 (12%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 K ++ A G GTR+ PIT+ + K++LP+ D+P+I+Y + + AGI+DILII+ E Sbjct: 2 KGIVLAGGAGTRLHPITRGVSKQLLPVYDKPMIYYPISVLMLAGIQDILIIS-----TPE 56 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 D SF+ L + + G + + Y +Q P GL A + E+ + GE Sbjct: 57 DL--PSFK-----------RLLGDGSQFG--IRLQYAKQPSPDGLAQAFIIGEEFIAGER 101 Query: 124 FAVLLGDDIIISKKPAIKQLIEVAERKN-TPVIGVESVPRELVSRYGIIEGELIENDLYR 182 A++LGD+I + KQL EVA R + V G + V E R+G+IE + EN Sbjct: 102 CALVLGDNIYFGQSFG-KQLREVASRNDGATVFGYQVVDAE---RFGVIEFD--EN---- 151 Query: 183 IKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNEI 241 L + P++ S+ A+ G Y ++ ++ +E P GE+++T ++ L K ++ Sbjct: 152 FNALSIEEKPQKPKSDWAVTGLYFYDKDVVEMAKEIKPSERGELEITTLNEMYLAKGKL 210 >gb|AAF59934.1| (AF237895) dTDP-D-glucose synthase [Streptomyces antibioticus] Length = 356 Score = 99.8 bits (245), Expect = 3e-20 Identities = 73/253 (28%), Positives = 122/253 (47%), Gaps = 31/253 (12%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 KA++ A G GTR+ PIT + K+++ + ++PV+ Y +E AGI D+ +I G Sbjct: 2 KALVLAGGSGTRLRPITHTSAKQLVAVANKPVLFYGLEAIAAAGITDVGLIVG------- 54 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 D + E+ + + K +DI Y+ Q +PLGL A+L A ++ + Sbjct: 55 ---DTAGEVRAAVGDGAKFG-----------LDITYIEQSRPLGLAHAVLIAHTYLGDDD 100 Query: 124 FAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLYRI 183 F + LGD+ I+ I L+ P + S +G+ E +D R+ Sbjct: 101 FVMYLGDNFIVG---GIDDLVRTFRDGRPPAARILLTHVSDPSAFGVAE----LDDDGRV 153 Query: 184 KRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILL-NKNEIL 242 L EK P+ S++A++G Y P I + +R P GE+++T A+Q L+ N +I Sbjct: 154 VGLEEK--PRHPKSDLALVGVYFFTPAIHEAVRAIEPSWRGELEITHAIQHLIDNGADIQ 211 Query: 243 AKRIEGERYDIGS 255 + IEG D G+ Sbjct: 212 SMVIEGYWKDTGN 224 >gb|AAD12523.1| (U02258) Homology to UDP pyrophosphorylase M76548 [Mycoplasma genitalium] Length = 103 Score = 99.5 bits (244), Expect = 4e-20 Identities = 50/102 (49%), Positives = 67/102 (65%) Query: 59 KRAIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKH 118 K AI D+FD LE L ++ KL+ +E+E+I + I++VRQK GLGDAIL+AE Sbjct: 2 KTAILDHFDYDLILENALIQKNKLQEHKEIEDIANLAHIFFVRQKNQDGLGDAILFAESF 61 Query: 119 VNGEPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESV 160 V E FAVLLGDD++ SK+PA+KQ +E N IGV+ V Sbjct: 62 VGNEDFAVLLGDDVVFSKEPALKQCLEAYYETNCQTIGVQEV 103 >pir||T51105 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) [validated] - Streptomyces antibioticus (ATCC 11891) >gi|5902169|gb|AAD55453.1| (AF055579) dTDP-D-glucose synthase [Streptomyces antibioticus] Length = 356 Score = 99.1 bits (243), Expect = 5e-20 Identities = 73/253 (28%), Positives = 122/253 (47%), Gaps = 31/253 (12%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 KA++ A G GTR+ PIT + K+++ + ++PV+ Y +E AGI D+ +I G Sbjct: 2 KALVLAGGSGTRLRPITHTSAKQLVAVANKPVLFYGLEAIAAAGITDVGLIVG------- 54 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 D + E+ + + K +DI Y+ Q +PLGL A+L A ++ + Sbjct: 55 ---DTAGEVPRAVGDGAKFG-----------LDITYIEQSRPLGLAHAVLIAHTYLGDDD 100 Query: 124 FAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLYRI 183 F + LGD+ I+ I L+ P + S +G+ E +D R+ Sbjct: 101 FVMYLGDNFIVG---GIDDLVRTFRDGRRPAARILLTHVSDPSGFGVAE----LDDDGRV 153 Query: 184 KRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILL-NKNEIL 242 L EK P+ S++A++G Y P I + +R P GE+++T A+Q L+ N +I Sbjct: 154 VGLEEK--PRHPKSDLALVGVYFFTPAIHEAVRAIEPSWRGELEITHAIQHLIDNGADIQ 211 Query: 243 AKRIEGERYDIGS 255 + IEG D G+ Sbjct: 212 SMVIEGYWKDTGN 224 >gb|AAB47843.1| (U61226) RfbA [Leptospira interrogans] >gi|5814321|gb|AAD52189.1|AF144879_28 (AF144879) unknown [Leptospira interrogans] Length = 294 Score = 98.7 bits (242), Expect = 7e-20 Identities = 77/249 (30%), Positives = 121/249 (47%), Gaps = 30/249 (12%) Query: 3 RKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAI 62 RK +I A G GTR+ P+T + K++LP+ D+P+I+Y + + AGI++IL+I+ +A Sbjct: 4 RKGIILAGGSGTRLYPVTYVVSKQLLPVYDKPMIYYPLTTLMLAGIKEILLIS--TPQAT 61 Query: 63 EDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGE 122 Y E L + ++ G + I Y Q P GL A E VNG Sbjct: 62 PMY----------------KELLGDGKQWG--ISIEYAVQPNPGGLAQAYWIGENFVNGH 103 Query: 123 PFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLYR 182 P ++LGD+I + L+E A +K V + P RYG++E + R Sbjct: 104 PSVLILGDNIYFGHN--LASLLENASKKENGST-VFAYPVHDPERYGVVEFD----SERR 156 Query: 183 IKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNEIL 242 + EKPS + SN A+ G Y E+ +I + P GE+++TD +I L + IL Sbjct: 157 AVSIEEKPS--KPKSNYAVTGLYFYDEEVVNIAKSIKPSARGELEITDVNRIYLERG-IL 213 Query: 243 AKRIEGERY 251 ++ G Y Sbjct: 214 NVQVMGRGY 222 >gb|AAD28517.1|AF126354_3 (AF126354) BlmD [Streptomyces bluensis] Length = 355 Score = 98.7 bits (242), Expect = 7e-20 Identities = 70/253 (27%), Positives = 133/253 (51%), Gaps = 32/253 (12%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 KA++ A G GTR+ PIT + K+++P+ ++PV+ Y +E AGI+++ +I G Sbjct: 2 KALVLAGGSGTRLRPITHTSAKQLVPVANKPVLFYGLEAIAAAGIKNVGLIVG------- 54 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 D S ++ EA+ + + G + I Y+ Q++PLGL A+L + ++ + Sbjct: 55 ---DMSGDIS---------EAVGDGSKFG--LSISYIEQREPLGLAHAVLISRDYLGEDD 100 Query: 124 FAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLYRI 183 FA+ LGD+ I+ I + + R++ P + +G+ E + R+ Sbjct: 101 FAMYLGDNFIVG---GIDEPVR-EFRRDRPDAHLLLTHVSDPQSFGVAELDATG----RV 152 Query: 184 KRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNK-NEIL 242 + L EK P+ S++A++G Y+ P I + +R P GE+++TDA+Q L++ ++ Sbjct: 153 RGLEEK--PRHPKSDLALVGVYLFSPAIHEAVRAVKPSWRGELEITDAVQWLIDTGKDVR 210 Query: 243 AKRIEGERYDIGS 255 +++I G D G+ Sbjct: 211 SRQITGYWKDTGN 223 >emb|CAA80332.1| (Z22611) OAC3 [Azorhizobium caulinodans] Length = 213 Score = 97.5 bits (239), Expect = 2e-19 Identities = 73/239 (30%), Positives = 118/239 (48%), Gaps = 31/239 (12%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 K +I A G GTR+ PIT + K++LP+ D+P+I+Y + + AGI DILIIT Sbjct: 2 KGIILAGGSGTRLHPITLVVSKQLLPVYDKPMIYYPLCTLMMAGIRDILIIT-------- 53 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 + E + K L++ + G ++I Y Q P GL DA + + V + Sbjct: 54 ----TPHDSELFQK------LLKDGSQFG--LNISYAVQPSPRGLADAFIVGREFVGNDR 101 Query: 124 FAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLYRI 183 A++LGD++ + +L++ A+ + T V P RYG++E ++ ++ Sbjct: 102 VALVLGDNLFFGH--GLPELLKTAQARETGAT-VFGYPVTDPERYGVVE----MDETGKV 154 Query: 184 KRLVEKP-SPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNEI 241 L EKP PK SN+A+ G Y + DI P GEI++TD + L+ E+ Sbjct: 155 LSLEEKPLKPK---SNLAVTGLYFYDNRVVDIAANLAPSPRGEIEITDVNKAYLDLGEL 210 >pir||C36864 probable glucose-1-phosphate thymidylyltransferase - Azorhizobium caulinodans (fragment) Length = 210 Score = 97.5 bits (239), Expect = 2e-19 Identities = 73/239 (30%), Positives = 118/239 (48%), Gaps = 31/239 (12%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 K +I A G GTR+ PIT + K++LP+ D+P+I+Y + + AGI DILIIT Sbjct: 2 KGIILAGGSGTRLHPITLVVSKQLLPVYDKPMIYYPLCTLMMAGIRDILIIT-------- 53 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 + E + K L++ + G ++I Y Q P GL DA + + V + Sbjct: 54 ----TPHDSELFQK------LLKDGSQFG--LNISYAVQPSPRGLADAFIVGREFVGNDR 101 Query: 124 FAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLYRI 183 A++LGD++ + +L++ A+ + T V P RYG++E ++ ++ Sbjct: 102 VALVLGDNLFFGH--GLPELLKTAQARETGAT-VFGYPVTDPERYGVVE----MDETGKV 154 Query: 184 KRLVEKP-SPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNEI 241 L EKP PK SN+A+ G Y + DI P GEI++TD + L+ E+ Sbjct: 155 LSLEEKPLKPK---SNLAVTGLYFYDNRVVDIAANLAPSPRGEIEITDVNKAYLDLGEL 210 >emb|CAA07386.1| (AJ006985) StrD [Streptomyces glaucescens] Length = 356 Score = 97.1 bits (238), Expect = 2e-19 Identities = 73/257 (28%), Positives = 131/257 (50%), Gaps = 40/257 (15%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 KA++ A G G R+ PIT + K+++P+ ++PV+ Y +E AGI D+ I+ G I Sbjct: 2 KALVLAGGAGPRLRPITHTSAKQLVPVANKPVLFYGLEAIAAAGITDVGIVVGDTVAEI- 60 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 EA+ + + G +D+ Y+ Q+KPLGLG + + ++ + Sbjct: 61 ------------------TEAVGDGSKFG--LDVTYIPQRKPLGLGHGVRISRDYLGDDD 100 Query: 124 FAVLLGDDIIISKKPAIKQLIEVAERKNTP----VIGVESVPRELVSRYGIIEGELIEND 179 FA+ LGD+ ++ I Q I A R + P ++ S PR +G+ E ++ Sbjct: 101 FAMYLGDNFVVG---GIDQPIR-AFRTHRPDAHLLLTRVSDPRS----FGVAE----LDE 148 Query: 180 LYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNK- 238 R++ L EKP+ S++A++G Y+ P I + +R P GE+++T A+Q L+++ Sbjct: 149 RGRVRHLEEKPT--HPGSDLALVGVYLFSPAIHEAVRAIEPSWRGELEITHAVQWLIDEG 206 Query: 239 NEILAKRIEGERYDIGS 255 ++ + I G D G+ Sbjct: 207 KDVRSTLISGYWKDTGN 223 >gb|AAD13545.1| (AF080235) NDP-hexose synthetase homolog [Streptomyces cyanogenus] Length = 355 Score = 97.1 bits (238), Expect = 2e-19 Identities = 74/264 (28%), Positives = 127/264 (48%), Gaps = 32/264 (12%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 KA++ + G GTR+ P + SMPK+++PI ++PV+ +V+ G+ +I +I G Sbjct: 2 KALVLSGGSGTRLRPFSHSMPKQLIPIANKPVLEHVLRNVRDLGVTEIGVIVG------- 54 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 DR+ +++ + + L V+I Y+ Q+ PLGL + A + + Sbjct: 55 ---DRAEQIQAVIGDGSALG-----------VEITYIPQEAPLGLAHCVELARPFLGDDD 100 Query: 124 FAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLYRI 183 F + LGD+++ I E + + V VP +G+ EL + R+ Sbjct: 101 FVMYLGDNMLPEGVERIAD--EFTAGRPAAQVVVHKVPDP--RAFGV--AELAADG--RV 152 Query: 184 KRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQ-ILLNKNEIL 242 +RLVEK P+E S++A+IG Y P I + P GE+++TDA+Q ++ N + Sbjct: 153 ERLVEK--PQEPKSDLALIGVYFFTPAIHKAVAAIEPSARGELEITDAIQWLVANGDRFK 210 Query: 243 AKRIEGERYDIGSKFGFVMANLKL 266 A +G D G + N KL Sbjct: 211 ANEYKGYWKDTGRIEDVLECNRKL 234 >gb|AAG18702.1| (AE004975) glucose-1-phosphate thymidylyltransferase; GraD3 [Halobacterium sp. NRC-1] Length = 238 Score = 96.0 bits (235), Expect = 5e-19 Identities = 73/233 (31%), Positives = 109/233 (46%), Gaps = 31/233 (13%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 KAV+ AAG GTR+ P T +PK ++ + +P++ + E + GI+D++++ G K I Sbjct: 2 KAVVLAAGEGTRLRPRTADLPKPLVEVNGKPILTHCFEILLDLGIDDVVVVVGYEKDKII 61 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 D + SF +DI Y Q + LGL A+L AE +V+ + Sbjct: 62 DRYGDSF----------------------RAIDIEYAHQSERLGLAHAVLTAEPYVDSD- 98 Query: 124 FAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLYRI 183 F VL GD+I + + L E VE V E + + E +D + Sbjct: 99 FVVLNGDNIYSANFSEV--LAHHTESGADITFPVEEVSTEEATSGAVCE----LDDDRAV 152 Query: 184 KRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILL 236 LVEKP+ E PSN A Y+L P IF R P GE +L DA+ +L+ Sbjct: 153 TGLVEKPA--EPPSNYAPTAFYVLPPAIFPACRVIRPSERGEYELADAIDLLI 203 >sp|P95778|RMLA_STRMU GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (DTDP-GLUCOSE SYNTHASE) (DTDP-GLUCOSE PYROPHOSPHORYLASE) >gi|1813345|dbj|BAA11247.1| (D78182) glucose-1-phosphate thymidyltransferase [Streptococcus mutans] Length = 289 Score = 94.4 bits (231), Expect = 1e-18 Identities = 68/246 (27%), Positives = 124/246 (49%), Gaps = 33/246 (13%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 K +I A G GTR+ P+T++ K+++P+ D+P+I+Y + + AGI+DILII+ Sbjct: 2 KGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLAGIKDILIIS-------- 53 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 +L + E L++ E G + + Y Q P GL A + E+ + + Sbjct: 54 ----TPQDLPRF------KELLQDGSEFG--IKLSYAEQPSPDGLAQAFIIGEEFIGDDH 101 Query: 124 FAVLLGDDIIISKKPAIKQLIEVAERKNT--PVIGVESVPRELVSRYGIIEGELIENDLY 181 A++LGD+I P + ++++ A K + V G + E R+G++E +ND Sbjct: 102 VALILGDNIYYG--PGLSRMLQKAASKESGATVFGYQVKDPE---RFGVVE---FDNDRN 153 Query: 182 RIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNEI 241 I + EK P+ S+ A+ G Y + DI + P GE+++TD + L++ ++ Sbjct: 154 AIS-IEEK--PEHPKSHYAVTGLYFYDNSVVDIAKNIKPSPRGELEITDVNKAYLDRGDL 210 Query: 242 LAKRIE 247 + +E Sbjct: 211 SVEVME 216 >pir||G69101 mannose-1-phosphate guanyltransferase - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622888|gb|AAB86225.1| (AE000931) mannose-1-phosphate guanyltransferase [Methanobacterium thermoautotrophicum] Length = 385 Score = 93.2 bits (228), Expect = 3e-18 Identities = 64/208 (30%), Positives = 104/208 (49%), Gaps = 31/208 (14%) Query: 6 VIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIEDY 65 V+ A G GTR+ P+T S PK ++P+ +RP++ Y++ + +G +++ G Sbjct: 7 VVMAGGKGTRIRPLTFSRPKPLVPVANRPILDYIIHRVLDSGYSKVVMTLG--------- 57 Query: 66 FDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEPFA 125 YLK++ + L E EI D + +KKPLG + A +N E F Sbjct: 58 ---------YLKDQIRSHVLAEYPEI----DFRFSVEKKPLGTAGGVKAAASEIN-ETFI 103 Query: 126 VLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLYRIKR 185 VL GD I ++++++ +KN ++ V P E S YGI + +D +IKR Sbjct: 104 VLSGDVIF---DLDLREMVKFHRKKNA-LVTVALTPVEDPSHYGI----AVLDDDGKIKR 155 Query: 186 LVEKPSPKEAPSNIAIIGRYILIPEIFD 213 EKP P+E S IA G Y++ PE+ + Sbjct: 156 FHEKPRPEEVFSKIANAGIYVMEPEVIE 183 >pir||S58687 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) strD - Streptomyces violaceoruber >gi|763512|gb|AAA99940.1| (L37334) dTDP-glucose synthetase [Streptomyces violaceoruber] Length = 352 Score = 92.8 bits (227), Expect = 4e-18 Identities = 63/244 (25%), Positives = 116/244 (46%), Gaps = 32/244 (13%) Query: 13 GTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIEDYFDRSFEL 72 G R+ P T SMPK+++P+ ++P++ + +E G+E++ ++ G DR+ E+ Sbjct: 10 GDRLRPFTYSMPKQLVPVANKPILVHCLENVRAIGVEEVAVVVG----------DRADEV 59 Query: 73 EYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEPFAVLLGDDI 132 + + +D+ Y++Q+ PLGL + AE+ + E F + LGD+I Sbjct: 60 RAVVGDGSAFG-----------LDVTYLQQEAPLGLAHCVSIAEEFLGDEDFVMYLGDNI 108 Query: 133 IISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLYRIKRLVEKPSP 192 + + ++ + PR YG+ E + R+ LVEK P Sbjct: 109 LAEGIAESARAFRDERSAARLLLTKVADPR----AYGVAETDATG----RVHALVEK--P 158 Query: 193 KEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNE-ILAKRIEGERY 251 + S++A+IG Y + D +R P GE+++TDA+Q L+ + + ++A G Sbjct: 159 ERPRSDLAVIGVYFFTAAVHDAVRAIEPSARGELEITDAIQYLVERGDRVVADEYTGYWK 218 Query: 252 DIGS 255 D GS Sbjct: 219 DTGS 222 >gb|AAC35920.1| (AF071085) putative glucose-1-phosphate thymidyl transferase [Enterococcus faecalis] Length = 288 Score = 92.4 bits (226), Expect = 5e-18 Identities = 67/241 (27%), Positives = 116/241 (47%), Gaps = 35/241 (14%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILII-TGKGKRAI 62 K +I A G GTR+ P+TK+ K+++PI D+P+I+Y + + AGI +ILII T + Sbjct: 2 KGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLAGINEILIISTPEDTPRF 61 Query: 63 EDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGE 122 E F +L + I Y Q+ P GL A + E+ + + Sbjct: 62 ESLFGDGHDLG---------------------IHIEYAVQESPDGLAQAFIIGEEFIGDD 100 Query: 123 PFAVLLGDDIIISKKPAIKQLIEVAERKNT--PVIGVESVPRELVSRYGIIEGELIENDL 180 ++LGD+I + ++++ A K + V G E R+G++E + + Sbjct: 101 SVCLVLGDNIYYG--GGLSKMLQRAASKESGATVFGYHVNDPE---RFGVVEFD----EE 151 Query: 181 YRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNE 240 R + EKP+ + SN A+ G Y E+ +I + P GE+++TD ++ L KN+ Sbjct: 152 MRALSIEEKPA--QPKSNYAVTGLYFYDNEVVEIAKGIKPSERGELEITDVNKVYLEKNK 209 Query: 241 I 241 + Sbjct: 210 L 210 >pir||T00103 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) - Actinobacillus actinomycetemcomitans >gi|3132255|dbj|BAA28132.1| (AB010415) glucose-1-phosphate-thymidylyltransferase [Actinobacillus actinomycetemcomitans] Length = 290 Score = 92.4 bits (226), Expect = 5e-18 Identities = 73/240 (30%), Positives = 116/240 (47%), Gaps = 33/240 (13%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 K +I A G GTR+ PIT+ + K++LP+ D+P+I+Y + + AG+ DILIIT E Sbjct: 2 KGIILAGGSGTRLYPITRGVSKQLLPVYDKPMIYYPLSVLMLAGVRDILIIT-----TPE 56 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 D + SF+ L + E G V++ Y Q P GL A L E+ +NG+ Sbjct: 57 D--NESFK-----------RLLGDGSEFG--VNLQYTIQPSPDGLAQAFLIGERFINGDS 101 Query: 124 FAVLLGDDIIISKKPAIKQLIEVAERKNTPVIG-VESVPRELVSRYGIIEGELIENDLYR 182 ++LGD+I + VA V G + P R+G++E + EN ++ Sbjct: 102 CCLVLGDNIFYGQNFTQMLQQAVARPYGATVFGYLVKDP----GRFGVVEFD--EN--FK 153 Query: 183 IKRLVEKP-SPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNEI 241 + EKP PK SN A+ G Y + D ++ P GE+++T ++ L + Sbjct: 154 AVSIEEKPVQPK---SNYAVTGLYFYDNRVVDFAKQVKPSARGELEITTLNEMYLKDGSL 210 >dbj|BAA94403.1| (AB041266) D-glucose-1-phosphate thymidylyltransferase [Actinobacillus actinomycetemcomitans] Length = 290 Score = 92.4 bits (226), Expect = 5e-18 Identities = 73/240 (30%), Positives = 116/240 (47%), Gaps = 33/240 (13%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 K +I A G GTR+ PIT+ + K++LP+ D+P+I+Y + + AG+ DILIIT E Sbjct: 2 KGIILAGGSGTRLYPITRGVSKQLLPVYDKPMIYYPLSVLMLAGVRDILIIT-----TPE 56 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 D + SF+ L + E G V++ Y Q P GL A L E+ +NG+ Sbjct: 57 D--NESFK-----------RLLGDGSEFG--VNLQYAIQPSPDGLAQAFLIGERFINGDS 101 Query: 124 FAVLLGDDIIISKKPAIKQLIEVAERKNTPVIG-VESVPRELVSRYGIIEGELIENDLYR 182 ++LGD+I + VA V G + P R+G++E + EN ++ Sbjct: 102 CCLVLGDNIFYGQNFTQMLQQAVARPYGATVFGYLVKDP----GRFGVVEFD--EN--FK 153 Query: 183 IKRLVEKP-SPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNEI 241 + EKP PK SN A+ G Y + D ++ P GE+++T ++ L + Sbjct: 154 AVSIEEKPIQPK---SNYAVTGLYFYDNRVVDFAKQVKPSARGELEITTLNEMYLKDGSL 210 >gb|AAK43317.1| Sugar phosphate nucleotydyl transferase [Sulfolobus solfataricus] Length = 253 Score = 92.4 bits (226), Expect = 5e-18 Identities = 83/258 (32%), Positives = 117/258 (45%), Gaps = 49/258 (18%) Query: 1 MIRKAVIPAAGLGTRMLPITKSMPKEMLPI--------VDRPVIHYVVEEAVKAGIEDIL 52 M+ KAVI +AG G+RM IT +PK +LP+ V RPVI +++ K G+E Sbjct: 1 MLEKAVITSAGKGSRMKHITNVLPKALLPLFVTENGGKVTRPVIDLIMDSLNKIGVEKFC 60 Query: 53 IITGKGKRAIEDY-FDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDA 111 I+ G+ + Y FDR+ +V Q P G GDA Sbjct: 61 IVVGRNGMLLMQYLFDRT---------------------------PTFVFQDMPKGFGDA 93 Query: 112 ILYAEKHVNGEPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGII 171 +L AE EPF V D ++ ++K L E V+ V V E SRYG++ Sbjct: 94 VLRAEDFSTNEPFFVHADDGVLTKGYDSLKLLFN--EISPDGVLLVRRV--ENPSRYGVV 149 Query: 172 ----EGELIENDLYRIKRLVEKP-SPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEI 226 +G + LYR+ EKP PK SN+AI YI P IF LR+ E+ Sbjct: 150 TVQDKGMYNGHKLYRVIDAEEKPLHPK---SNLAIAAVYIFKPSIFSALRQIKVEEGKEL 206 Query: 227 QLTDAL-QILLNKNEILA 243 +LT + +LL+ E+ A Sbjct: 207 ELTYGIHNLLLDGKEVYA 224 >dbj|BAA19634.1| (AB002668) glucose-1-phosphate-thymidylyltransferase [Actinobacillus actinomycetemcomitans] Length = 290 Score = 91.7 bits (224), Expect = 9e-18 Identities = 71/239 (29%), Positives = 115/239 (47%), Gaps = 31/239 (12%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 K +I A G GTR+ PIT+ + K++LP+ D+P+I+Y + + AG+ DILIIT E Sbjct: 2 KGIILAGGSGTRLYPITRGVSKQLLPVYDKPMIYYPLSVLMLAGVRDILIIT-----TPE 56 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 D + SF+ L + E G V++ Y Q P GL A L E +NG+ Sbjct: 57 D--NESFK-----------RLLGDGSEFG--VNLQYAIQPSPDGLAQAFLIGEGFINGDS 101 Query: 124 FAVLLGDDIIISKKPAIKQLIEVAERKNTPVIG-VESVPRELVSRYGIIEGELIENDLYR 182 ++LGD+I + VA V G + P R+G++E + EN ++ Sbjct: 102 CCLVLGDNIFYGQNFTQMLQQAVARPYGATVFGYLVKDP----GRFGVVEFD--EN--FK 153 Query: 183 IKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNEI 241 + EKP+ + SN A+ G Y + D ++ P GE+++T ++ L + Sbjct: 154 AVSIEEKPA--QPKSNYAVTGLYFYDNRVVDFAKQVKPSARGELEITTLNEMYLKDGSL 210 >gb|AAC68682.1| (AF079762) alpha-D-glucose-1-phosphate thymidylyltransferase [Streptomyces venezuelae] Length = 292 Score = 90.9 bits (222), Expect = 2e-17 Identities = 75/278 (26%), Positives = 131/278 (46%), Gaps = 40/278 (14%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 K ++ A G GTR+ P T + K++LP+ ++P+I+Y + + GI +I II+ Sbjct: 2 KGIVLAGGSGTRLHPATSVISKQILPVYNKPMIYYPLSVLMLGGIREIQIIS-------- 53 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 + EL L G+ +G +++ Y QK+P G+ DA+L +H+ + Sbjct: 54 --TPQHIELFQSLLGNGR--------HLG--IELDYAVQKEPAGIADALLVGAEHIGDDT 101 Query: 124 FAVLLGDDIIISKKPAIKQLI--EVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLY 181 A++LGD+I P + L+ +A + G P + RYG+ E + Sbjct: 102 CALILGDNIF--HGPGLYTLLRDSIARLDGCVLFG---YPVKDPERYGVAEVDATG---- 152 Query: 182 RIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNEI 241 R+ LVEK P + SN+A+ G Y+ ++ DI + P GE+++TD N + Sbjct: 153 RLTDLVEK--PVKPRSNLAVTGLYLYDNDVVDIAKNIRPSPRGELEITDV-------NRV 203 Query: 242 LAKRIEGERYDIGSKFGFVMANLKLSLRREELRNEVLK 279 +R E ++G F ++ SL R +VL+ Sbjct: 204 YLERGRAELVNLGRGFAWLDTGTHDSLLRAAQYVQVLE 241 >emb|CAC12985.1| (AJ250327) glucose-1-phosphate thymidyltransferase [Acetobacter xylinus] Length = 306 Score = 90.5 bits (221), Expect = 2e-17 Identities = 68/243 (27%), Positives = 118/243 (47%), Gaps = 29/243 (11%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 K ++ A G GTRM P+T+++ K++LP+ D+P+I Y + + AGI DI+II+ + Sbjct: 11 KGILLAGGSGTRMHPMTQAVSKQLLPVYDKPMIFYPLSTLMLAGIRDIMIISTPADLPLF 70 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 F + + ++G V Y Q P G+ AI+ A+ ++ P Sbjct: 71 RRF------------------VGDGSDMG--VTFTYREQPSPDGIAQAIVIADDWLDDAP 110 Query: 124 FAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLYRI 183 A++LGD++I + +QL E A R + V RYG++ + L Sbjct: 111 CALILGDNLIFADHLG-RQLREAAARPTGDTVFAYEVRDP--ERYGVVSFSADGHAL--- 164 Query: 184 KRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNEILA 243 +VEKP+ + SN A+ G Y + + R P GE+++TD +I L K+++ Sbjct: 165 -DIVEKPTSPQ--SNWAVTGLYFYDGRVREYARSLKPSSRGELEITDLNRIYLQKDDLHV 221 Query: 244 KRI 246 +R+ Sbjct: 222 QRL 224 >gb|AAD31799.1|AF128273_2 (AF128273) TDP-glucose synthase homolog [Streptomyces griseus] Length = 289 Score = 90.5 bits (221), Expect = 2e-17 Identities = 70/238 (29%), Positives = 113/238 (47%), Gaps = 31/238 (13%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 K +I A G GTR+ PIT + K++LP+ D+P+I+Y + + AGI DI I+ Sbjct: 2 KGIILAGGHGTRLQPITFGVSKQLLPVYDKPMIYYPLSVLMLAGITDIQIVAAPDGL--- 58 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 +G L + ++G +D+ Y Q KP GL DA L +E H+ + Sbjct: 59 ---------------QGFRRLLGDGSDLG--LDLSYAEQDKPRGLADAFLVSEDHIGDDA 101 Query: 124 FAVLLGDDIIISKKPAIKQLI-EVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLYR 182 A++LGD++ P ++ VA + V+ P RYG+ E + N Sbjct: 102 VALVLGDNLF--HGPGFSDILRRVALDLDGAVL--FGYPVRDPERYGVGEVDGAGN---- 153 Query: 183 IKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNE 240 + L EKP+ SN+AI G Y ++ +I R P GE+++TD + L + + Sbjct: 154 LTALEEKPA--RPRSNLAITGLYFYDNDVVEIARSLRPSERGELEITDVNRRYLERGK 209 >gb|AAC44969.1| (U09239) glucose-1-phosphate thymidyl transferase [Streptococcus pneumoniae] Length = 289 Score = 90.5 bits (221), Expect = 2e-17 Identities = 63/240 (26%), Positives = 120/240 (49%), Gaps = 33/240 (13%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 K +I A G GTR+ P+T++ K+++P+ D+P+I+Y + + AGI DILII+ Sbjct: 2 KGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLAGIRDILIIS-------- 53 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 +L + E L++ E G + + Y Q P GL A + E+ ++ + Sbjct: 54 ----TPQDLHRF------QELLQDGSEFG--LKLSYAEQPSPDGLAQAFIIGEEFISDDS 101 Query: 124 FAVLLGDDIIISKKPAIKQLIEVAERKNT--PVIGVESVPRELVSRYGIIEGELIENDLY 181 A++LGD+I + ++++ A K + V G E R+G++E + D+ Sbjct: 102 VALILGDNIYHGS--GLSKMLQKAASKESGATVFGYHVKDPE---RFGVVE---FDQDM- 152 Query: 182 RIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNEI 241 K + + P++ SN A+ G Y ++ +I + P GE+++TD + L++ ++ Sbjct: 153 --KAISIEEKPEQPRSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDRGDL 210 >dbj|BAB07082.1| (AP001518) spore coat polysaccharide synthesis (glucose-1-phosphate thymidyltransferase) [Bacillus halodurans] Length = 247 Score = 90.5 bits (221), Expect = 2e-17 Identities = 66/229 (28%), Positives = 117/229 (50%), Gaps = 29/229 (12%) Query: 2 IRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRA 61 +RKAVI A G G+R+ PIT+ + K +LP+ P+I++ + +A +AG+ +ILI+T + A Sbjct: 1 MRKAVILAGGTGSRLSPITRVINKHLLPVGSYPMIYWSILKAKEAGLHEILILTSREHLA 60 Query: 62 IEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNG 121 ++ L + +++G V ++Y Q + G+ A+ AE V Sbjct: 61 ------------------AFIQLLGDGKDLG--VHLHYTIQDQADGIASALSLAEHFVGD 100 Query: 122 EPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLY 181 E F VLLGD++ A Q E ++K + ++ V +RYGI ++ Sbjct: 101 EKFLVLLGDNLFADPLTAYVQQYE--KQKEGAFVLLKEVRDP--TRYGI---AFLDETKQ 153 Query: 182 RIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTD 230 +IK++VEKP+ + S + G Y+ +F + + P GE+++TD Sbjct: 154 KIKKIVEKPNMQ--GSAYCVTGIYMYDRTVFSFIEQIAPSARGELEITD 200 >dbj|BAA82533.1| (AB030032) glucose-1-phosphate thymidylyltransferase [Actinobacillus actinomycetemcomitans] Length = 290 Score = 90.1 bits (220), Expect = 3e-17 Identities = 71/239 (29%), Positives = 114/239 (46%), Gaps = 31/239 (12%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 K +I A G GTR+ PIT+ + K++LP+ D+P+I+Y + + AGI DILIIT E Sbjct: 2 KGIILAGGSGTRLYPITRGVSKQLLPVYDKPMIYYPLSVLMLAGIRDILIIT-----TPE 56 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 D + SF+ L + G V++ Y Q P GL A L E +NG+ Sbjct: 57 D--NESFK-----------RLLGDGSNFG--VNLQYAIQPSPDGLAQAFLIGEAFINGDS 101 Query: 124 FAVLLGDDIIISKKPAIKQLIEVAERKNTPVIG-VESVPRELVSRYGIIEGELIENDLYR 182 ++LGD+I + VA V G + P R+G++E + EN ++ Sbjct: 102 CCLVLGDNIFYGQHFTQMLQRAVARPYGATVFGYLVKDP----GRFGVVEFD--EN--FK 153 Query: 183 IKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNEI 241 + EKP+ + SN A+ G Y + D ++ P GE+++T ++ L + Sbjct: 154 AVSIEEKPA--QPKSNYAVTGLYFYDNRVVDFAKQVKPSARGELEITTLNEMYLKDGSL 210 >pir||S49053 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) tylA1 [validated] - Streptomyces fradiae >gi|473599|gb|AAA21343.1| (U08223) dTDP-glucose synthase [Streptomyces fradiae] Length = 303 Score = 89.7 bits (219), Expect = 4e-17 Identities = 67/237 (28%), Positives = 115/237 (48%), Gaps = 34/237 (14%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 K +I A G GTR+ P+T ++ K++LP+ D+P+I+Y + + AGI +I II+ K Sbjct: 10 KGIILAGGSGTRLRPLTGTLSKQLLPVYDKPMIYYPLSVLMLAGIREIQIISSK------ 63 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 D+ D L L E + +G + I Y Q++P G+ +A L +H+ G+ Sbjct: 64 DHLDLFRSL------------LGEGDRLG--LSISYAEQREPRGIAEAFLIGARHIGGDD 109 Query: 124 FAVLLGDDIIISKKPAIKQLI--EVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLY 181 A++LGD++ P ++ VA + G P + RYG+ GE+ Sbjct: 110 AALILGDNVF--HGPGFSSVLTGTVARLDGCELFG---YPVKDAHRYGV--GEIDSGG-- 160 Query: 182 RIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNK 238 R+ L EKP P + Y+ ++ +I R P GE+++TD ++ L + Sbjct: 161 RLLSLEEKPRRPLEPGRHRL---YLYTNDVVEIARTISPSARGELEITDVNKVYLEQ 214 >pir||E71207 probable glucose-1-phosphate thymidylyltransferase - Pyrococcus horikoshii >gi|3258369|dbj|BAA31052.1| (AP000007) 419aa long hypothetical glucose-1-phosphate thymidylyltransferase [Pyrococcus horikoshii] Length = 419 Score = 89.7 bits (219), Expect = 4e-17 Identities = 77/261 (29%), Positives = 126/261 (47%), Gaps = 35/261 (13%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 KAVI AAG G R+ P+T PK +L I ++P+I Y++E E I+++ K ++ IE Sbjct: 2 KAVILAAGKGERLRPLTDDRPKPILKIANKPIIEYILENLDPFVDEFIIVVKYKKEKIIE 61 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 D E++ K I YV Q G AI A+ + E Sbjct: 62 TLGD-----EFHGK------------------PITYVVQGDEEGTARAIYSAKDAIIDEE 98 Query: 124 FAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLYRI 183 F + GD I ++ AI+ L+ RK G+ E +S+ G++E ++N+L + Sbjct: 99 FFAINGD--IYFEQEAIRGLLH-TYRKMKADGGIVVKKFENLSQLGLVE---VKNNL--V 150 Query: 184 KRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNE-IL 242 K+++EKP E +N+ I YI E+FD + ET GE ++TD + I++ + + I+ Sbjct: 151 KKIIEKPGKMEGFANLGI---YIFNSEVFDFIEETEKSERGEYEITDTINIMIERGKRIV 207 Query: 243 AKRIEGERYDIGSKFGFVMAN 263 +G DIG + + N Sbjct: 208 YFEYKGFWSDIGRPWDLLEVN 228 >sp|P37744|RBA1_ECOLI GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (DTDP-GLUCOSE SYNTHASE) (DTDP-GLUCOSE PYROPHOSPHORYLASE) >gi|7434865|pir||F64969 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) - Escherichia coli (strain K-12) >gi|1736729|dbj|BAA15881.1| (D90841) Glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) (dTDP-glucose synthase) (dTDP-glucose pyrophosphorylase). [Escherichia coli] >gi|1736742|dbj|BAA15893.1| (D90842) Glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) (dTDP-glucose synthase) (dTDP-glucose pyrophosphorylase). [Escherichia coli] >gi|1788351|gb|AAC75100.1| (AE000294) glucose-1-phosphate thymidylyltransferase [Escherichia coli K12] >gi|2665491|gb|AAB88400.1| (U09876) glucose-1-phosphate thymidylyltransferase [Escherichia coli] Length = 293 Score = 88.5 bits (216), Expect = 8e-17 Identities = 68/245 (27%), Positives = 114/245 (45%), Gaps = 39/245 (15%) Query: 2 IRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILII-----TG 56 +RK +I A G GTR+ P+T ++ K++LPI D+P+I+Y + + AGI DILII T Sbjct: 3 MRKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTP 62 Query: 57 KGKRAIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAE 116 + ++ + D L+Y + Q P GL A + E Sbjct: 63 RFQQLLGDGSQWGLNLQYKV-------------------------QPSPDGLAQAFIIGE 97 Query: 117 KHVNGEPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELI 176 + + G+ A++LGD+I + +L+E A K + V + RYG++E + Sbjct: 98 EFIGGDDCALVLGDNIFYGHD--LPKLMEAAVNKESGAT-VFAYHVNDPERYGVVEFDKN 154 Query: 177 ENDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILL 236 + L EK P E SN A+ G Y ++ + + P GE+++TD +I L Sbjct: 155 GTAI----SLEEK--PLEPKSNYAVTGLYFYDNDVVQMAKNLKPSARGELEITDINRIYL 208 Query: 237 NKNEI 241 + + Sbjct: 209 EQGRL 213 >pir||I69650 glucose-1-phosphate thymidylyltransferase - Escherichia coli Length = 293 Score = 88.5 bits (216), Expect = 8e-17 Identities = 68/245 (27%), Positives = 114/245 (45%), Gaps = 39/245 (15%) Query: 2 IRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILII-----TG 56 +RK +I A G GTR+ P+T ++ K++LPI D+P+I+Y + + AGI DILII T Sbjct: 3 MRKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTP 62 Query: 57 KGKRAIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAE 116 + ++ + D L+Y + Q P GL A + E Sbjct: 63 RFQQLLGDGSQWGLNLQYKV-------------------------QPSPDGLAQAFIIGE 97 Query: 117 KHVNGEPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELI 176 + + G+ A++LGD+I + +L+E A K + V + RYG++E + Sbjct: 98 EFIGGDDCALVLGDNIFYGHD--LPKLMEAAVNKESGAT-VFAYHVNDPERYGVVEFDKN 154 Query: 177 ENDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILL 236 + L EK P E SN A+ G Y ++ + + P GE+++TD +I L Sbjct: 155 GTAI----SLEEK--PLEPKSNYAVTGLYFYDNDVVQMAKNLKPSARGELEITDINRIYL 208 Query: 237 NKNEI 241 + + Sbjct: 209 EQGRL 213 >pir||D55213 rfbA protein - Shigella flexneri (strain 2a) >gi|294898|gb|AAA53681.1| (L14842) glucose-1-phosphate thymidylyltransferase [Shigella flexneri] Length = 292 Score = 88.2 bits (215), Expect = 1e-16 Identities = 66/244 (27%), Positives = 116/244 (47%), Gaps = 39/244 (15%) Query: 3 RKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILII-----TGK 57 RK +I A G GTR+ P+T ++ K++LPI D+P+I+Y + + AGI DILII T + Sbjct: 4 RKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPR 63 Query: 58 GKRAIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEK 117 ++ + D L+Y + Q P GL A + E+ Sbjct: 64 FQQLLGDGSQWGLNLQYKV-------------------------QPSPDGLAQAFIIGEE 98 Query: 118 HVNGEPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIE 177 + G+ A++LGD+I + +L++ A + + V + RYG++E + Sbjct: 99 FIGGDDCALVLGDNIFYGHD--LPKLMDTAVNRESGAT-VFAYHVNDPERYGVVEFD--- 152 Query: 178 NDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLN 237 D L EK P+E SN A+ G Y ++ ++ + P GE+++TD +I ++ Sbjct: 153 -DNGTAISLEEK--PQEPKSNYAVTGLYFYDNDVVEMAKNLKPSARGELEITDINRIYMD 209 Query: 238 KNEI 241 + + Sbjct: 210 QGRL 213 >pir||S78498 probable glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) - Neisseria meningitidis >gi|388934|gb|AAA63158.1| (L09188) TDP-deoxyglucose-epimerase [Neisseria meningitidis] Length = 328 Score = 87.8 bits (214), Expect = 1e-16 Identities = 67/238 (28%), Positives = 118/238 (49%), Gaps = 29/238 (12%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 K +I A G GTR+ PIT+ + K++LP+ D+P+I+Y + + AGI DIL+IT A E Sbjct: 42 KGIILAGGSGTRLYPITRGVSKQLLPVYDKPMIYYPLSVLMLAGIRDILVIT-----APE 96 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 D + SF+ L + ++G + I Y Q P GL A + E+ + + Sbjct: 97 D--NASFK-----------RLLGDGSDLG--ISISYAVQPSPDGLAQAFIIGEEFIGNDN 141 Query: 124 FAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLYRI 183 ++LGD+I + + Q ++ A R+ T V + + R+G++E N+ +R Sbjct: 142 VCLVLGDNIFYGQ--SFTQTLKQAARQ-THGATVFAYQVKNPERFGVVE----FNENFRA 194 Query: 184 KRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNEI 241 + EK P+ S+ A+ G Y + ++ P GE+++TD ++ L + Sbjct: 195 VSIEEK--PQRPKSDWAVTGLYFYDNRAVEFAKQIKPSARGELEITDLNRMYLEDGSL 250 >gb|AAG09515.1|AF279619_3 (AF279619) glucose-1-phosphate thymidylyltransferase [Salmonella enterica] Length = 292 Score = 87.8 bits (214), Expect = 1e-16 Identities = 70/239 (29%), Positives = 116/239 (48%), Gaps = 29/239 (12%) Query: 3 RKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAI 62 RK +I A G GTR+ P+T ++ K++LPI D+P+I+Y + + AGI DILII+ Sbjct: 4 RKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSMLMLAGIRDILIISTPQDTP- 62 Query: 63 EDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGE 122 FE + L E + G +++ Y Q P GL A + E+ + + Sbjct: 63 ------RFE-----------QLLGEGSQWG--LNLQYKVQPTPDGLAQAFIIGEEFIGND 103 Query: 123 PFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLYR 182 A++LGD+I + +L+E A K + V + RYG++E + D Sbjct: 104 DCALVLGDNIFYGHD--LPRLMETAVNKESGAT-VFAYHVNDPERYGVVE---FDKDGTA 157 Query: 183 IKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNEI 241 I L EKP E SN A+ G Y ++ ++ + P GE+++TD +I + + + Sbjct: 158 IS-LEEKPL--EPKSNYAVTGLYFYDNDVVEMAKNLKPSARGELEITDINRIYMEQGRL 213 >pir||T30872 dNDP-glucose synthase - Streptomyces viridochromogenes >gi|1911169|emb|CAA72714.1| (Y11985) dNDP-glucose synthase [Streptomyces viridochromogenes] Length = 355 Score = 87.4 bits (213), Expect = 2e-16 Identities = 64/232 (27%), Positives = 115/232 (48%), Gaps = 31/232 (13%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 KA+I G+G+R+ PIT + K+++P+ +R V+ YV++ +AGI ++ I+ G I+ Sbjct: 2 KALILVGGVGSRLRPITHTSAKQLVPVANRTVLSYVLDSIKEAGISEVGIVVGATAAEIQ 61 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 ++ + E G +D+ Y++Q P GL DA+L + + + Sbjct: 62 -------------------ASVGDGAEFG--LDVTYIQQDAPRGLADAVLVSRDFLGDDD 100 Query: 124 FAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLYRI 183 F + LGD+ ++ I + R++ P V R+G+ EL EN R+ Sbjct: 101 FVMYLGDNYVVD---GIVDFV-ADFRRDKPAAQVMLARVADPRRFGV--AELDENG--RV 152 Query: 184 KRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQIL 235 +VEK P++ S++AI+G Y + + + P E+++TDALQ L Sbjct: 153 TAVVEK--PQDPRSDLAIVGVYAFSSAVHEAVAGIRPSWRNELEITDALQWL 202 >pir||D75597 glucose-1-phosphate thymidylyltransferase - Deinococcus radiodurans (strain R1) >gi|6460561|gb|AAF12267.1|AE001862_93 (AE001862) glucose-1-phosphate thymidylyltransferase [Deinococcus radiodurans] Length = 296 Score = 87.4 bits (213), Expect = 2e-16 Identities = 67/244 (27%), Positives = 109/244 (44%), Gaps = 39/244 (15%) Query: 3 RKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILII-----TGK 57 RK +I A G GTR+ P T ++ K++LPI D+P+I+Y + + G+ +ILII T + Sbjct: 5 RKGIILAGGSGTRLYPATLAVSKQLLPIYDKPMIYYPLTTLMLGGMREILIISTPEDTPR 64 Query: 58 GKRAIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEK 117 K+ + D LEY + Q KP GL A L E Sbjct: 65 FKQLLGDGSQWGIALEYAV-------------------------QPKPEGLAQAFLIGED 99 Query: 118 HVNGEPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIE 177 V G P +++LGD+I + L++ A K R+ RYG+++ + Sbjct: 100 FVQGHPSSLILGDNIFYGND--LSDLMQAANAKENGATVFAYQVRD-PERYGVVDFDRSG 156 Query: 178 NDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLN 237 R + EKP+ + S+ A+ G Y + +I R P GE+++TD + L Sbjct: 157 ----RALSIEEKPA--QPKSDFAVTGLYFYDERVSEIARSIKPSPRGELEITDLNNVYLE 210 Query: 238 KNEI 241 + + Sbjct: 211 EGAL 214 >sp|P37779|RFBA_SHIFL GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (DTDP-GLUCOSE SYNTHASE) (DTDP-GLUCOSE PYROPHOSPHORYLASE) >gi|541220|pir||S41536 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) - Shigella flexneri (serotype 2a) >gi|454900|emb|CAA50769.1| (X71970) rfbC [Shigella flexneri] Length = 290 Score = 87.0 bits (212), Expect = 2e-16 Identities = 66/246 (26%), Positives = 117/246 (46%), Gaps = 39/246 (15%) Query: 3 RKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILII-----TGK 57 RK +I A G GTR+ P+T ++ K++LPI D+P+I+Y + + AGI DILII T + Sbjct: 4 RKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPR 63 Query: 58 GKRAIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEK 117 ++ + D L+Y + Q P GL A + E+ Sbjct: 64 FQQLLGDGSQWGLNLQYKV-------------------------QPSPDGLAQAFIIGEE 98 Query: 118 HVNGEPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIE 177 + G+ A++LGD+I + +L++ A + + V + RYG++E + Sbjct: 99 FIGGDDCALVLGDNIFYGHD--LPKLMDTAVNRESGAT-VFAYHVNDPERYGVVEFD--- 152 Query: 178 NDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLN 237 D L EK P++ SN A+ G Y ++ ++ + P GE+++TD +I ++ Sbjct: 153 -DNGTPISLEEK--PQQPKSNYAVTGLYFYDNDVVEMAKNLKPSARGELEITDINRIYMD 209 Query: 238 KNEILA 243 + + A Sbjct: 210 QGRLSA 215 >gb|AAF73461.1|AF264025_12 (AF264025) putative dTDP-1-glucose synthase; AknY [Streptomyces galilaeus] Length = 291 Score = 86.6 bits (211), Expect = 3e-16 Identities = 78/269 (28%), Positives = 124/269 (45%), Gaps = 44/269 (16%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 K +I A G GTR+ PIT S+ K++LP+ D+P+I+Y + + A I +IL+I +R +E Sbjct: 2 KGIILAGGSGTRLHPITVSVSKQLLPVGDKPMIYYPLSVLMLADIREILLIC--TERDLE 59 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 + L + ++G +D Y Q +P GL DA + HV + Sbjct: 60 QF----------------RRLLGDGSQLGLRID--YAVQNRPAGLADAFVIGADHVGDDD 101 Query: 124 FAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIE----GELIEND 179 A++LGD+I V + + + G P E RYG+ E G+L+ Sbjct: 102 VALVLGDNIFHGHHFYDLLQSNVHDVQGCVLFG---YPVEDPERYGVGETDASGQLVS-- 156 Query: 180 LYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKN 239 L EK P S++AI G Y+ E+ DI + P GE+++TD +N+N Sbjct: 157 ------LEEK--PLRPRSDLAITGLYLYDNEVVDIAKNLRPSPRGELEITD-----VNRN 203 Query: 240 EILAKRIEGERYDIGSKFGFVMANLKLSL 268 + R D+G F ++ A SL Sbjct: 204 YLARGR--ARLVDLGRGFAWLDAGTPESL 230 >gb|AAG09511.1|AF279618_3 (AF279618) glucose-1-phosphate thymidylyltransferase [Salmonella enterica] Length = 292 Score = 86.6 bits (211), Expect = 3e-16 Identities = 68/245 (27%), Positives = 114/245 (45%), Gaps = 41/245 (16%) Query: 3 RKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILII-----TGK 57 RK +I A G GTR+ P+T ++ K++LPI D+P+I+Y + + AGI DILII T + Sbjct: 4 RKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPR 63 Query: 58 GKRAIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEK 117 ++ + D L+Y + Q P GL A + E+ Sbjct: 64 FQQLLGDGSQWGLNLQYKV-------------------------QPNPDGLAQAFIIGEE 98 Query: 118 HVNGEPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIE 177 + + A++LGD+I + +L++VA K G+ + RYG++E + + Sbjct: 99 FIGNDDCALVLGDNIFYGHD--LPKLMDVAVNKENGAYGIAYHVND-PERYGVVEFD--Q 153 Query: 178 NDLYRIKRLVEKP-SPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILL 236 N L EKP PK SN A+ G Y + + + P GE+++TD +I + Sbjct: 154 NG--TAVSLEEKPLQPK---SNYAVTGLYFYDNSVVAMAKNLKPSARGELEITDINRIYM 208 Query: 237 NKNEI 241 + + Sbjct: 209 EQGRL 213 >sp|P08075|STRD_STRGR GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (DTDP-GLUCOSE SYNTHASE) (DTDP-GLUCOSE PYROPHOSPHORYLASE) (SUGAR-NUCLEOTIDYLATION ENZYME) >gi|49261|emb|CAA68514.1| (Y00459) put. sugaractivating enzyme [Streptomyces griseus] Length = 355 Score = 86.2 bits (210), Expect = 4e-16 Identities = 73/273 (26%), Positives = 131/273 (47%), Gaps = 35/273 (12%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 KA++ A G GTR+ PIT + K+++P+ ++PV+ Y +E AGI D+ I+ G Sbjct: 2 KALVLAGGTGTRLRPITHTSAKQLVPVANKPVLFYGLEAIRAAGIIDVGIVVG------- 54 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 D + E+ + A+ + G + + Y+ Q KPLGL +L + + + Sbjct: 55 ---DTADEI---------VAAVGDGSRFG--LKVSYIPQSKPLGLAHCVLISRDFLGEDD 100 Query: 124 FAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLYRI 183 F + LGD+ ++ + A ++ PR +G+ E +D ++ Sbjct: 101 FIMYLGDNFVVGVVEDSVREFRAARPDAHLMLTRVPEPRS----FGVAE----LSDSGQV 152 Query: 184 KRLVEKPS-PKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNK-NEI 241 L EKP+ PK S++A++G Y+ P I + + P GE+++TDA+Q L++ ++ Sbjct: 153 LGLEEKPAHPK---SDLALVGVYLFSPAIHEAVAAITPSWRGELEITDAVQWLIDAGRDV 209 Query: 242 LAKRIEGERYDIGSKFGFVMANLKLSLRREELR 274 + I G D G+ + N +L L E R Sbjct: 210 RSTVISGYWKDTGNVTDMLEVN-RLVLETTEPR 241 >pir||A26984 strD protein - Streptomyces griseus Length = 355 Score = 86.2 bits (210), Expect = 4e-16 Identities = 73/273 (26%), Positives = 131/273 (47%), Gaps = 35/273 (12%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 KA++ A G GTR+ PIT + K+++P+ ++PV+ Y +E AGI D+ I+ G Sbjct: 2 KALVLAGGTGTRLRPITHTSAKQLVPVANKPVLFYGLEAIRAAGIIDVGIVVG------- 54 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 D + E+ + A+ + G + + Y+ Q KPLGL +L + + + Sbjct: 55 ---DTADEI---------VAAVGDGSRFG--LKVSYIPQSKPLGLAHCVLISRDFLGEDD 100 Query: 124 FAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLYRI 183 F + LGD+ ++ + A ++ PR +G+ E +D ++ Sbjct: 101 FIMYLGDNFVVGVVEDSVREFRAARPDAHLMLTRVPEPRS----FGVAE----LSDSGQV 152 Query: 184 KRLVEKPS-PKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNK-NEI 241 L EKP+ PK S++A++G Y+ P I + + P GE+++TDA+Q L++ ++ Sbjct: 153 LGLEEKPAHPK---SDLALVGVYLFSPAIHEAVAAITPSWRGELEITDAVQWLIDAGRDV 209 Query: 242 LAKRIEGERYDIGSKFGFVMANLKLSLRREELR 274 + I G D G+ + N +L L E R Sbjct: 210 RSTVISGYWKDTGNVTDMLEVN-RLVLETTEPR 241 >pir||D83000 glucose-1-phosphate thymidylyltransferase PA5163 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9951465|gb|AAG08548.1|AE004929_3 (AE004929) glucose-1-phosphate thymidylyltransferase [Pseudomonas aeruginosa] Length = 293 Score = 86.2 bits (210), Expect = 4e-16 Identities = 71/253 (28%), Positives = 117/253 (46%), Gaps = 34/253 (13%) Query: 1 MIRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKR 60 M RK +I A G GTR+ P T ++ K++LP+ D+P+I+Y + + AGI +ILII+ Sbjct: 1 MKRKGIILAGGSGTRLHPATLAISKQLLPVYDKPMIYYPLSTLMLAGIREILIISTPQDT 60 Query: 61 AIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVN 120 F+ + L + G +D+ Y Q P GL A L E + Sbjct: 61 P-------RFQ-----------QLLGDGSNWG--LDLQYAVQPSPDGLAQAFLIGESFIG 100 Query: 121 GEPFAVLLGDDIIISKKPAIKQLIEVAERKNT--PVIGVESVPRELVSRYGIIEGELIEN 178 + A++LGD++ +L+ A ++ T V + E RYG++E + Sbjct: 101 NDLSALVLGDNLYYGHD--FHELLGSASQRQTGASVFAYHVLDPE---RYGVVEFD---- 151 Query: 179 DLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNK 238 K + + P E SN A+ G Y ++ DI R+ P GE+++TD + L + Sbjct: 152 --QGGKAISLEEKPLEPKSNYAVTGLYFYDQQVVDIARDLKPSPRGELEITDVNRAYLER 209 Query: 239 NEILAKRIEGERY 251 + L+ I G Y Sbjct: 210 GQ-LSVEIMGRGY 221 >sp|P55253|RBA2_ECOLI GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (DTDP-GLUCOSE SYNTHASE) (DTDP-GLUCOSE PYROPHOSPHORYLASE) >gi|7434862|pir||S78544 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) - Escherichia coli (strain VW187 ) >gi|799234|gb|AAC63614.1| (AF125322) RmlA [Escherichia coli] Length = 293 Score = 86.2 bits (210), Expect = 4e-16 Identities = 70/245 (28%), Positives = 116/245 (46%), Gaps = 40/245 (16%) Query: 3 RKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILII-----TGK 57 RK +I A G GTR+ P+T ++ K++LPI D+P+I+Y + + AGI DILII T + Sbjct: 4 RKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPR 63 Query: 58 GKRAIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEK 117 ++ + D L+Y + Q P GL A + E Sbjct: 64 FQQLLGDGSQWGLNLQYKV-------------------------QPSPDGLAQAFIIGED 98 Query: 118 HVNGEPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIE 177 + G+ A++LGD+I + +L+E A K + V + RYG++E + Sbjct: 99 FIGGDDCALVLGDNIFYGHD--LPKLMEAAVNKESGAT-VFAYHVNDPERYGVVE---FD 152 Query: 178 NDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRET-PPGRDGEIQLTDALQILL 236 N+ I L EK P E SN A+ G Y ++ ++ R+ P GE+++TD +I + Sbjct: 153 NNGTAIS-LEEK--PLEPKSNYAVTGLYFYDNDVVEMARKNLKPSARGELEITDINRIYM 209 Query: 237 NKNEI 241 + + Sbjct: 210 EQGRL 214 >sp|P55255|RFBA_NEIMB GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (DTDP-GLUCOSE SYNTHASE) (DTDP-GLUCOSE PYROPHOSPHORYLASE) >gi|11261719|pir||B81240 glucose-1-phosphate thymidylyltransferase NMB0080, NMB0062 [imported] - Neisseria meningitidis (group B strain MD58) >gi|7225282|gb|AAF40530.1| (AE002365) glucose-1-phosphate thymidylyltransferase [Neisseria meningitidis MC58] >gi|7225298|gb|AAF40544.1| (AE002367) glucose-1-phosphate thymidylyltransferase [Neisseria meningitidis MC58] Length = 288 Score = 85.8 bits (209), Expect = 5e-16 Identities = 65/238 (27%), Positives = 114/238 (47%), Gaps = 29/238 (12%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 K +I A G GTR+ PIT+ + K++LP+ D+P+I+Y + + AGI DIL+IT A E Sbjct: 2 KGIILAGGSGTRLYPITRGVSKQLLPVYDKPMIYYPLSVLMLAGIRDILVIT-----APE 56 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 D + SF+ L + + G + I Y Q P GL A + E+ + + Sbjct: 57 D--NASFK-----------RLLGDGSDFG--ISISYAVQPSPDGLAQAFIIGEEFIGNDN 101 Query: 124 FAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLYRI 183 ++LGD+I + + L + A + + + V R+G++E N+ +R Sbjct: 102 VCLVLGDNIFYGQS-FTQTLKQAAAQTHGATVFAYQVKNP--ERFGVVE----FNENFRA 154 Query: 184 KRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNEI 241 + EK P+ S+ A+ G Y + ++ P GE+++TD ++ L + Sbjct: 155 VSIEEK--PQRPKSDWAVTGLYFYDNRAVEFAKQLKPSARGELEITDLNRMYLEDGSL 210 >gb|AAG23610.1|AF244661_1 (AF244661) glucose-1-phosphate thymidylyltransferase [Carboxydothermus hydrogenoformans] Length = 197 Score = 85.4 bits (208), Expect = 7e-16 Identities = 55/176 (31%), Positives = 97/176 (54%), Gaps = 13/176 (7%) Query: 83 EALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEPFAVLLGDDIIISKKPAIKQ 142 E + + G ++ Q+KPLGL A+ A+ ++ + F + LGD++I S IK+ Sbjct: 21 EIKKSITNAGFPAKFTFILQEKPLGLAHAVKVAKDYLEDDDFIMYLGDNLINS---GIKE 77 Query: 143 LIE-VAERKNTPVIGVESVPRELVSRYGIIEGELIENDLYRIKRLVEKPSPKEAPSNIAI 201 +E E + I ++ V +R+G+ + ++ ++++RL+EKP KE PSN+A+ Sbjct: 78 FVEEYKENRYDATILLKEVQDP--TRFGVA----VVDENFKVQRLIEKP--KEPPSNLAL 129 Query: 202 IGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNEIL-AKRIEGERYDIGSK 256 +G YI P+IF + P GE+++TDA+Q L+ ++ A +I G D G K Sbjct: 130 VGIYIFSPKIFSAIDRIKPSWRGELEITDAIQELITSGGMVQAHKITGWWLDTGKK 185 >gb|AAC37050.1| (L09189) glucose-1-phosphate thymidyl transferase [Neisseria meningitidis] Length = 301 Score = 85.4 bits (208), Expect = 7e-16 Identities = 66/238 (27%), Positives = 117/238 (48%), Gaps = 29/238 (12%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 K +I A G GTR+ PIT+ + K++LP+ D+P+I+Y + + AGI DIL+IT A E Sbjct: 15 KGIILAGGSGTRLYPITRGVSKQLLPVYDKPMIYYPLSVLMLAGIRDILVIT-----APE 69 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 D + SF+ L + + G + I Y Q P GL A + E+ + + Sbjct: 70 D--NASFK-----------RLLGDGSDFG--ISISYAVQPSPDGLAQAFIIGEEFIGNDN 114 Query: 124 FAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLYRI 183 ++LGD+I + + Q ++ A R+ T V + + R+G++E N+ +R Sbjct: 115 VCLVLGDNIFYGQ--SFTQTLKQAARQ-THGATVFAYQVKNPERFGVVE----FNENFRA 167 Query: 184 KRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNEI 241 + EK P+ S+ A+ G Y + ++ P GE++++D ++ L + Sbjct: 168 VSIEEK--PQRPKSDWAVTGLYFYDNRAVEFAKQLKPSARGELEISDLNRMYLEDGSL 223 >pir||D64437 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) - Methanococcus jannaschii >gi|1591746|gb|AAB99104.1| (U67553) glucose-1-phosphate thymidylyltransferase (strD) [Methanococcus jannaschii] Length = 408 Score = 85.4 bits (208), Expect = 7e-16 Identities = 71/263 (26%), Positives = 127/263 (47%), Gaps = 51/263 (19%) Query: 5 AVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIED 64 A+I AG G R+ P+T++ PK M+PI +P++ +++E+ V+ +++I +I K I D Sbjct: 3 AIILCAGKGERLRPLTENRPKPMIPIAGKPILQHIIEK-VEDLVDNIYLIVKYKKEKIVD 61 Query: 65 YFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEPF 124 YF ++++ E+G+++ G G A+L A+ +V+ E F Sbjct: 62 YFKNHPKIKFL--EQGEID-----------------------GTGQAVLTAKDYVDDE-F 95 Query: 125 AVLLGDDII---ISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLY 181 V+ GD I + + K + V E KN GV ++ +D Sbjct: 96 LVINGDIIFEDDLEEFLKYKYAVAVKEVKNPENFGV-----------------VVLDDEN 138 Query: 182 RIKRLVEKP-SPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNE 240 I L EKP +PK SN+ G Y +IF+++ +T GE +LTDA++ L+ + + Sbjct: 139 NIIELQEKPENPK---SNLINAGIYKFDKKIFELIEKTKISERGERELTDAIKHLIKEEK 195 Query: 241 ILAKRIEGERYDIGSKFGFVMAN 263 + ++ G D+G + + AN Sbjct: 196 VKGIKLNGYWNDVGRPWDILEAN 218 >emb|CAA77210.1| (Y18523) dTDP-glucose synthase [Actinoplanes sp. 50/110] Length = 303 Score = 85.0 bits (207), Expect = 9e-16 Identities = 63/240 (26%), Positives = 118/240 (48%), Gaps = 34/240 (14%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 + ++ A G G+R+ P+T ++ K+++P+ D+P+I+Y + V GI +IL+IT + + A Sbjct: 2 RGILLAGGTGSRLRPVTWAVSKQLMPVYDKPMIYYPLATLVSCGIREILVITTETEAA-- 59 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 F R L G LR + + Q++P G+ +A L E+ + G P Sbjct: 60 -QFQR-------LLGDGSQWGLR----------LEFAVQQRPGGIAEAFLIGEEFLAGGP 101 Query: 124 FAVLLGDDII--ISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLY 181 A++LGD+++ + +P +++ E A V GV S YG++E + Sbjct: 102 VALMLGDNLLHGVDFRPCVQRARETA---GGHVFGVAVAD---PSAYGVVEFDAAG---- 151 Query: 182 RIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNEI 241 R+ + EKP +P A+ G Y+ ++ + R P GE+++T+ Q L + + Sbjct: 152 RVLSIEEKPVRPRSP--YAVPGFYLYDADVVETARSLRPSARGELEITEVNQAYLRRGAL 209 >gb|AAG23575.1|AF244626_1 (AF244626) glucose-1-P thymidylyltransferase [Carboxydothermus hydrogenoformans] Length = 203 Score = 85.0 bits (207), Expect = 9e-16 Identities = 60/208 (28%), Positives = 106/208 (50%), Gaps = 14/208 (6%) Query: 56 GKGKRAIEDYFDRSF-ELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILY 114 G+ + IED D ++ + + + G ++ Q+KPLGL A+ Sbjct: 2 GRDRSGIEDIIDAGITDIGVIIAPETGEXIKKSITNAGFPAKFTFILQEKPLGLAHAVKV 61 Query: 115 AEKHVNGEPFAVLLGDDIIISKKPAIKQLIE-VAERKNTPVIGVESVPRELVSRYGIIEG 173 A+ ++ + F + LGD++I S IK+ +E E + I ++ V +R+G+ Sbjct: 62 AKDYLEDDDFIMYLGDNLINS---GIKEFVEEYKENRYDATILLKEVQDP--TRFGVA-- 114 Query: 174 ELIENDLYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQ 233 + ++ + ++RL+EKP KE PSN+A++G YI P IF + P GE+++TDA+Q Sbjct: 115 --VVDENFXVQRLIEKP--KEPPSNLALVGIYIFSPXIFSAMTGIKPSWRGELEITDAIQ 170 Query: 234 ILLNKNEIL-AKRIEGERYDIGSKFGFV 260 L+ + ++ A I G D G K F+ Sbjct: 171 ELIYQGGVVKAHNITGWWLDTGEKRRFI 198 >gb|AAG09500.1|AF279615_3 (AF279615) glucose-1-phosphate thymidylyltransferase [Salmonella enterica] Length = 292 Score = 84.7 bits (206), Expect = 1e-15 Identities = 67/245 (27%), Positives = 114/245 (46%), Gaps = 41/245 (16%) Query: 3 RKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILII-----TGK 57 RK +I A G GTR+ P+T ++ K++LPI D+P+I+Y + + AGI DILII T + Sbjct: 4 RKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPR 63 Query: 58 GKRAIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEK 117 ++ + D L+Y + Q P GL A + E+ Sbjct: 64 FQQLLGDGSQWGLNLQYKV-------------------------QPSPDGLAQAFIIGEE 98 Query: 118 HVNGEPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIE 177 + + A++LGD+I + +L+E A K + V + RYG++E + Sbjct: 99 FIGNDDCALVLGDNIFYGHD--LPKLMEAAVNKESGAT-VFAYHVNDPERYGVVEFDQSG 155 Query: 178 NDLYRIKRLVEKP-SPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILL 236 + L EKP PK SN A+ G Y + ++ + P GE+++TD +I + Sbjct: 156 TAV----SLEEKPLQPK---SNYAVTGLYFYDNSVVEMAKNLKPSARGELEITDINRIYM 208 Query: 237 NKNEI 241 ++ + Sbjct: 209 DQGRL 213 >sp|P55254|RFBA_SALAN GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (DTDP-GLUCOSE SYNTHASE) (DTDP-GLUCOSE PYROPHOSPHORYLASE) >gi|96668|pir||S23342 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) [validated] - Salmonella choleraesuis >gi|46985|emb|CAA43074.1| (X60665) glucose-1-phosphate thymidylyltransferase [Salmonella enterica] Length = 292 Score = 84.3 bits (205), Expect = 2e-15 Identities = 67/245 (27%), Positives = 113/245 (45%), Gaps = 41/245 (16%) Query: 3 RKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILII-----TGK 57 RK +I A G GTR+ P+T ++ K++LPI D+P+I+Y + + AGI DILII T + Sbjct: 4 RKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPR 63 Query: 58 GKRAIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEK 117 ++ + D L+Y + Q P GL A + E+ Sbjct: 64 FQQLLGDGSQWGLNLQYKV-------------------------QPSPDGLAQAFIIGEE 98 Query: 118 HVNGEPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIE 177 + + A++LGD+I + +L+E A K + V + RYG++E + Sbjct: 99 FIGNDDCALVLGDNIFYGHD--LPKLMEAAVNKESGAT-VFAYHVNDPERYGVVEFDQSG 155 Query: 178 NDLYRIKRLVEKP-SPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILL 236 + L EKP PK SN A+ G Y + ++ + P GE+++TD +I + Sbjct: 156 TAV----SLEEKPLQPK---SNYAVTGLYFYDNSVVEMAKNLKPSARGELEITDINRIYM 208 Query: 237 NKNEI 241 + + Sbjct: 209 EQGRL 213 >emb|CAB01949.1| (Z79692) ExpA7 [Sinorhizobium meliloti] Length = 293 Score = 84.3 bits (205), Expect = 2e-15 Identities = 67/244 (27%), Positives = 116/244 (47%), Gaps = 30/244 (12%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 K +I A G GTR+ P+T S+ K++LP+ D+P+I+Y + + AGI +IL+IT R + Sbjct: 2 KGIILAGGRGTRLYPVTISVSKQLLPVHDKPMIYYPLGMLMLAGIREILVITMPRDRPL- 60 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 FE E L + + G + I Y Q +P GL +A + + Sbjct: 61 ------FE-----------ELLGDGSQFG--LAISYAEQPEPNGLAEAFIIGRDFIGNSS 101 Query: 124 FAVLLGDDIIISKKPAIKQLI-EVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLYR 182 A++LGD+I + +L + A R + I V + RYG++ + + R Sbjct: 102 VALILGDNIFYG--AGLPELCSDAAARPSGATIFAYRV--DDPERYGVVS---FDGETGR 154 Query: 183 IKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNEIL 242 + + EK P+ A S+ A+ G Y + +I P GE+++TD + L + ++ Sbjct: 155 AETIEEK--PELARSSWAVTGLYFYENSVLEIASSIKPSARGELEITDVNRAYLERGDLH 212 Query: 243 AKRI 246 R+ Sbjct: 213 VCRL 216 >emb|CAB88884.1| (AL353861) putative mannose-1-phosphate guanyltransferase [Streptomyces coelicolor A3(2)] Length = 831 Score = 83.9 bits (204), Expect = 2e-15 Identities = 68/272 (25%), Positives = 132/272 (48%), Gaps = 36/272 (13%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 KAV+ A G GTR+ P+T SMPK +LP+V+RP++ +V+ + G+ + ++ ++ Sbjct: 2 KAVVMAGGEGTRLRPMTSSMPKPLLPVVNRPIMEHVLRLLKRHGLNETVVTVQFLASLVK 61 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 +YF + EE+G +++ Y ++KPLG ++ AE+ + + Sbjct: 62 NYFG-------------------DGEELG--MELTYANEEKPLGTAGSVKNAEEALKDDA 100 Query: 124 FAVLLGDDIIISKKPAIKQLIEVAERKNTPV-IGVESVPRELVSRYGIIEGELIENDLYR 182 F V+ GD + + LI + K + V + + VP L +GI I ++ + Sbjct: 101 FLVISGDALTDFD---LTDLINFHKEKGSLVTVCLTRVPNPL--EFGI----TIVDEEGK 151 Query: 183 IKRLVEKPSPKEAPSNIAIIGRYILIPEIFDIL-RETPPGRDGEIQLTDALQILLNKNEI 241 ++R +EKP+ + S+ G Y++ PE+F+ + + P G++ Q++ I Sbjct: 152 VERFLEKPTWGQVFSDTVNTGIYVMEPEVFNYVDPDVPVDWSGDV----FPQLMKEGKPI 207 Query: 242 LAKRIEGERYDIGSKFGFVMANLKLSLRREEL 273 EG D+G+ +V A + R+ ++ Sbjct: 208 YGYVAEGYWEDVGTHESYVKAQADVLERKVDV 239 >gb|AAG09532.1|AF279623_3 (AF279623) glucose-1-phosphate thymidylyltransferase [Salmonella enterica] Length = 292 Score = 83.5 bits (203), Expect = 3e-15 Identities = 68/245 (27%), Positives = 114/245 (45%), Gaps = 41/245 (16%) Query: 3 RKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILII-----TGK 57 RK +I A G GTR+ P+T ++ K++LPI D+P+I+Y + + AGI DILII T + Sbjct: 4 RKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPR 63 Query: 58 GKRAIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEK 117 ++ + D L+Y + Q P GL A + E+ Sbjct: 64 FQQLLGDGSQWGLNLQYKV-------------------------QPNPDGLAQAFIIGEE 98 Query: 118 HVNGEPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIE 177 + + A++LGD+I + +L++VA K V + RYG++E + + Sbjct: 99 FIGNDDCALVLGDNIFYGHD--LPKLMDVAINKENGAT-VFAYHVNDPERYGVVEFD--Q 153 Query: 178 NDLYRIKRLVEKP-SPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILL 236 N L EKP PK SN A+ G Y + ++ + P GE+++TD +I + Sbjct: 154 NG--TAVSLEEKPLQPK---SNYAVTGLYFYDNSVVEMAKNLKPSARGELEITDINRIYM 208 Query: 237 NKNEI 241 + + Sbjct: 209 EQGRL 213 >gb|AAG09504.1|AF279616_3 (AF279616) glucose-1-phosphate thymidylyltransferase [Salmonella enterica] Length = 292 Score = 83.5 bits (203), Expect = 3e-15 Identities = 68/245 (27%), Positives = 115/245 (46%), Gaps = 41/245 (16%) Query: 3 RKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILII-----TGK 57 RK +I A G GTR+ P+T ++ K++LPI D+P+I+Y + + AGI DILII T + Sbjct: 4 RKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPR 63 Query: 58 GKRAIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEK 117 ++ + D L+Y + Q P GL A + E+ Sbjct: 64 FQQLLGDGSQWGLNLQYKV-------------------------QPSPDGLAQAFIIGEE 98 Query: 118 HVNGEPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIE 177 + + A++LGD+I + +L+E A K + V + RYG++E + + Sbjct: 99 FIGHDDCALVLGDNIFYGHD--LPKLMEAAVNKESGAT-VFAYHVNDPERYGVVEFD--Q 153 Query: 178 NDLYRIKRLVEKP-SPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILL 236 N L EKP PK SN A+ G Y + ++ + P GE+++TD +I + Sbjct: 154 NG--TAVSLEEKPLQPK---SNYAVTGLYFYDNSVVEMAKNLKPSARGELEITDINRIYM 208 Query: 237 NKNEI 241 ++ + Sbjct: 209 DQGRL 213 >sp|P26393|RFBA_SALTY GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (DTDP-GLUCOSE SYNTHASE) (DTDP-GLUCOSE PYROPHOSPHORYLASE) >gi|96785|pir||S15301 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) - Salmonella typhimurium >gi|47891|emb|CAA40117.1| (X56793) glucose-1-phosphate thymidylyltransferase [Salmonella enterica] Length = 292 Score = 83.1 bits (202), Expect = 4e-15 Identities = 67/245 (27%), Positives = 113/245 (45%), Gaps = 41/245 (16%) Query: 3 RKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILII-----TGK 57 RK +I A G GTR+ P+T ++ K++LPI D+P+I+Y + + AGI DILII T + Sbjct: 4 RKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPR 63 Query: 58 GKRAIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEK 117 ++ + D L+Y + Q P GL A + E+ Sbjct: 64 FQQLLGDGSQWGLNLQYKV-------------------------QPSPDGLAQAFIIGEE 98 Query: 118 HVNGEPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIE 177 + + A++LGD+I + +L+E A K + V + RYG++E + Sbjct: 99 FIGHDDCALVLGDNIFYGHD--LPKLMEAAVNKESGAT-VFAYHVNDPERYGVVEFDQKG 155 Query: 178 NDLYRIKRLVEKP-SPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILL 236 + L EKP PK SN A+ G Y + ++ + P GE+++TD +I + Sbjct: 156 TAV----SLEEKPLQPK---SNYAVTGLYFYDNSVVEMAKNLKPSARGELEITDINRIYM 208 Query: 237 NKNEI 241 + + Sbjct: 209 EQGRL 213 >gb|AAG09519.1|AF279620_3 (AF279620) glucose-1-phosphate thymidylyltransferase [Salmonella enterica] Length = 290 Score = 82.3 bits (200), Expect = 6e-15 Identities = 68/245 (27%), Positives = 113/245 (45%), Gaps = 41/245 (16%) Query: 3 RKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILII-----TGK 57 RK +I A G GTR+ P+T ++ K++LPI D+P+I+Y + + AGI DILII T + Sbjct: 4 RKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPR 63 Query: 58 GKRAIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEK 117 ++ + D L+Y + Q P GL A + E+ Sbjct: 64 FQQLLGDGSQWGLNLQYKV-------------------------QPNPDGLAQAFIIGEE 98 Query: 118 HVNGEPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIE 177 + + A++LGD+I + +L++VA K V + RYG++E + + Sbjct: 99 FIGNDDCALVLGDNIFYGHD--LPKLMDVAVNKENGAT-VFAYHVNDPERYGVVEFD--Q 153 Query: 178 NDLYRIKRLVEKP-SPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILL 236 N L EKP PK SN A+ G Y + + + P GE+++TD +I + Sbjct: 154 NG--TAVSLEEKPLQPK---SNYAVTGLYFYDNSVVAMAKNLKPSARGELEITDINRIYM 208 Query: 237 NKNEI 241 + + Sbjct: 209 EQGRL 213 >gb|AAG09524.1|AF279621_3 (AF279621) glucose-1-phosphate thymidylyltransferase [Salmonella enterica] Length = 292 Score = 82.3 bits (200), Expect = 6e-15 Identities = 67/245 (27%), Positives = 114/245 (46%), Gaps = 41/245 (16%) Query: 3 RKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILII-----TGK 57 RK +I A G GTR+ P+T ++ K++LPI D+P+I+Y + + AGI DILII T + Sbjct: 4 RKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPR 63 Query: 58 GKRAIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEK 117 ++ + D L+Y + Q P GL A + E+ Sbjct: 64 FQQLLGDGSQWGLNLQYKV-------------------------QPSPDGLAQAFIIGEE 98 Query: 118 HVNGEPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIE 177 + + A++LGD+I + +L++ A K V + RYG++E + + Sbjct: 99 FIGNDDCALVLGDNIFYGHD--LPKLMDAAVNKEDGAT-VFAYHVNDPERYGVVEFD--Q 153 Query: 178 NDLYRIKRLVEKP-SPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILL 236 N L EKP PK SN A+ G Y + ++ + P GE+++TD +I + Sbjct: 154 NG--TAVSLEEKPLQPK---SNYAVTGLYFYDNSVVEMAKNLKPSARGELEITDINRIYM 208 Query: 237 NKNEI 241 ++ + Sbjct: 209 DQGRL 213 >emb|CAA11943.1| (AJ224437) GalU protein [Erwinia carotovora subsp. carotovora] Length = 64 Score = 81.9 bits (199), Expect = 8e-15 Identities = 35/54 (64%), Positives = 47/54 (86%) Query: 2 IRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIIT 55 ++KAVIP AGLGTRMLP TK++PKEMLP+VD+P+I YVV E + AGI +I+++T Sbjct: 8 VKKAVIPVAGLGTRMLPATKAIPKEMLPLVDKPLIQYVVNECIAAGINEIILVT 61 >gb|AAG09536.1|AF279624_3 (AF279624) glucose-1-phosphate thymidylyltransferase [Salmonella enterica] Length = 289 Score = 80.8 bits (196), Expect = 2e-14 Identities = 80/312 (25%), Positives = 138/312 (43%), Gaps = 67/312 (21%) Query: 3 RKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILII-----TGK 57 RK +I A G GTR+ P+T ++ K++LPI D+P+I+Y + + AGI DILII T + Sbjct: 4 RKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPR 63 Query: 58 GKRAIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEK 117 ++ + D L+Y + Q P GL A + E+ Sbjct: 64 FQQLLGDGSQWGLNLQYKV-------------------------QLSPDGLAQAFIIGEE 98 Query: 118 HVNGEPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIE 177 + + A++LGD+I + +L++ A K V + RYG++E + Sbjct: 99 FIGNDDCALVLGDNIFYGHD--LPKLMDAAVNKEDGAT-VFAYHVNDPERYGVVEFDKNG 155 Query: 178 NDLYRIKRLVEKP-SPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILL 236 + L EKP PK SN A+ G Y + + + P GE+++TD +I + Sbjct: 156 TAV----SLEEKPLQPK---SNYAVTGLYFYDNSVVAMAKNLKPSARGELEITDINRIYM 208 Query: 237 NKNEILAKRIEGERY---DIGSKFGFVMAN-----------LKLS-----------LRRE 271 + L+ + G Y D G+ + A+ LK++ + +E Sbjct: 209 EQGR-LSVAMMGRGYAWLDTGTHQSLIEASNFIATIEERQGLKVACLEEIAYRKNYISKE 267 Query: 272 ELRNEVLKYLKS 283 +++N +LK+ KS Sbjct: 268 KIQNAILKFGKS 279 >gb|AAG09528.1|AF279622_3 (AF279622) glucose-1-phosphate thymidylyltransferase [Salmonella enterica] Length = 292 Score = 80.8 bits (196), Expect = 2e-14 Identities = 67/245 (27%), Positives = 113/245 (45%), Gaps = 41/245 (16%) Query: 3 RKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILII-----TGK 57 RK +I A G GTR+ P+T ++ K++LPI D+P+I+Y + + AGI DILII T + Sbjct: 4 RKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPR 63 Query: 58 GKRAIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEK 117 ++ + D L+Y + Q P GL A + E+ Sbjct: 64 FQQLLGDGSQWGLNLQYKV-------------------------QPSPDGLAQAFIIGEE 98 Query: 118 HVNGEPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIE 177 + + A++LGD+I + +L++ A K V + RYG++E + + Sbjct: 99 FIGNDDCALVLGDNIFYGHD--LPKLMDAAVNKEDGAT-VFAYHVNDPERYGVVEFD--Q 153 Query: 178 NDLYRIKRLVEKP-SPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILL 236 N L EKP PK SN A+ G Y + + ++ P GE+++TD +I + Sbjct: 154 NG--TAVSLEEKPLQPK---SNYAVTGLYFYDNSVVAMAKKLKPSARGELEITDINRIYM 208 Query: 237 NKNEI 241 + + Sbjct: 209 EQGRL 213 >gb|AAG09539.1|AF279625_3 (AF279625) glucose-1-phosphate thymidylyltransferase [Salmonella enterica] Length = 292 Score = 80.8 bits (196), Expect = 2e-14 Identities = 67/245 (27%), Positives = 113/245 (45%), Gaps = 41/245 (16%) Query: 3 RKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILII-----TGK 57 RK +I A G GT + P+T ++ K++LPI D+P+I+Y + + AGI DILII T + Sbjct: 4 RKGIILAGGSGTSLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPR 63 Query: 58 GKRAIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEK 117 ++ + D L+Y + Q P GL A + E+ Sbjct: 64 FQQLLGDGSQWGLNLQYKV-------------------------QPSPDGLAQAFIIGEE 98 Query: 118 HVNGEPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIE 177 + + A++LGD+I + +L+E A K + V + RYG++E + + Sbjct: 99 FIGHDDCALVLGDNIFYGHD--LPKLMEAAVNKESGAT-VFAYHVNDPERYGVVEFD--Q 153 Query: 178 NDLYRIKRLVEKP-SPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILL 236 N L EKP PK SN A+ G Y + ++ + P GE+++TD +I + Sbjct: 154 NG--TAVSLEEKPLQPK---SNYAVTGLYFYDNSVVEMAKNLKPSARGELEITDINRIYM 208 Query: 237 NKNEI 241 + + Sbjct: 209 EQGRL 213 >gb|AAG18651.1| (AE004970) glucose-1-phosphate thymidylyltransferase; GraD2 [Halobacterium sp. NRC-1] Length = 401 Score = 80.8 bits (196), Expect = 2e-14 Identities = 68/270 (25%), Positives = 120/270 (44%), Gaps = 40/270 (14%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 +A++ AAG GTRM P+T++ PK ++P+ ++ +V++ A +++ +I+ G I Sbjct: 2 QAIVVAAGRGTRMGPLTETRPKPLVPVAGATLLEHVLDAAAGV-VDEYVIVVGYRGDQIR 60 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 + S+ + Y Q G A+ AE HV G P Sbjct: 61 ERIGASYA----------------------GTPVVYAEQDTQEGTAHAVGCAEPHVEG-P 97 Query: 124 FAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLYRI 183 VL GD + S L+E + + V +P YG++E D R+ Sbjct: 98 CLVLNGDVYVTSA------LVEALAGADGTAMSV--MPVADPQSYGVVE----RGDDGRV 145 Query: 184 KRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNE--I 241 +VEKP+ + P+++A +G Y P +F+ + GE +LTDAL +++ + + Sbjct: 146 TNVVEKPT--DPPTDLANLGLYRFTPRVFEYIDTVERSERGEYELTDALARAIDREDGGV 203 Query: 242 LAKRIEGERYDIGSKFGFVMANLKLSLRRE 271 A +G D+G + + AN L +E Sbjct: 204 TAVSYDGPWLDVGRPWELLAANSALLAEQE 233 >gb|AAK41040.1| Sugar phosphate nucleotydyl transferase [Sulfolobus solfataricus] Length = 407 Score = 79.2 bits (192), Expect = 5e-14 Identities = 76/273 (27%), Positives = 131/273 (47%), Gaps = 47/273 (17%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 KAV+ AAG G R+ PIT + PK +P+++ P+I + +K I I+I+ + Sbjct: 2 KAVVLAAGKGERLEPITHTRPKPFVPVLETPLILRHI-RILKKYINKIIIVINSNHK--- 57 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNG-E 122 DYF + +E + V Q + G A+ AEK++ G E Sbjct: 58 DYF-------------------KTIEGVS------LVEQTEGKGTAAALRAAEKYLEGDE 92 Query: 123 PFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLYR 182 F V+ GD ++ ++ A+ +++ NT + + E ++G+I +++ R Sbjct: 93 EFLVIYGD--LLFEEDALDKIV------NTEGEAILARESEDPRKFGVI----VKDSENR 140 Query: 183 IKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNEIL 242 + R+VEK P+ PSNI G Y +IF + + GE +LTDA+ ++ NK +++ Sbjct: 141 LVRIVEK--PENPPSNIINAGIYKFTYDIFSYIDKISLSSRGEFELTDAVNLIGNKVKVV 198 Query: 243 AKRIEGERYDIGSKFGFVMANLKLSLRREELRN 275 G DIG + + AN K+ L +E+ RN Sbjct: 199 T--YNGIWLDIGRPWDLIEAN-KVLLDKEKDRN 228 >emb|CAB57558.1| (Y18930) glucose-1-phosphate thymidylyltransferase [Sulfolobus solfataricus] Length = 407 Score = 79.2 bits (192), Expect = 5e-14 Identities = 76/273 (27%), Positives = 131/273 (47%), Gaps = 47/273 (17%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 KAV+ AAG G R+ PIT + PK +P+++ P+I + +K I I+I+ + Sbjct: 2 KAVVLAAGKGERLEPITHTRPKPFVPVLETPLILRHI-RILKKYINKIIIVINSNHK--- 57 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNG-E 122 DYF + +E + V Q + G A+ AEK++ G E Sbjct: 58 DYF-------------------KTIEGVS------LVEQTEGKGTAAALRAAEKYLEGDE 92 Query: 123 PFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLYR 182 F V+ GD ++ ++ A+ +++ NT + + E ++G+I +++ R Sbjct: 93 EFLVIYGD--LLFEEDALDKIV------NTEGEAILARESEDPRKFGVI----VKDSENR 140 Query: 183 IKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNEIL 242 + R+VEK P+ PSNI G Y +IF + + GE +LTDA+ ++ NK +++ Sbjct: 141 LVRIVEK--PENPPSNIINAGIYKFTYDIFSYIDKISLSSRGEFELTDAVNLIGNKVKVV 198 Query: 243 AKRIEGERYDIGSKFGFVMANLKLSLRREELRN 275 G DIG + + AN K+ L +E+ RN Sbjct: 199 T--YNGIWLDIGRPWDLIEAN-KVLLDKEKDRN 228 >gb|AAF00210.1|AF164960_6 (AF164960) dNDP-glucose synthetase [Streptomyces fradiae] Length = 355 Score = 78.4 bits (190), Expect = 9e-14 Identities = 66/257 (25%), Positives = 119/257 (45%), Gaps = 40/257 (15%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 KA++ A G GTR+ P + SMPK+++PI + PV+ +V+ + G+ + +I G Sbjct: 2 KALVLAGGSGTRLRPFSYSMPKQLIPIANTPVLVHVLRNLRELGVTEAGVIVG------- 54 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 +R E+ L + E G + + Y+ Q P GL + + + Sbjct: 55 ---NRGPEIS---------AVLGDGAEFG--MRVTYIPQDAPRGLAHTVAITRDFLCDDD 100 Query: 124 FAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIE----GELIEND 179 F + LGD+++ ++ I V+ PR +G+ E GE++ Sbjct: 101 FVMYLGDNMLPDGVVDMRGGIHRPSAGGQVVVYKVPDPRS----FGVAELGPQGEVL--- 153 Query: 180 LYRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKN 239 RLVEK P++ S++A++G Y I D + P GE+++TDA+Q L++ Sbjct: 154 -----RLVEK--PRDPRSDMALVGVYFFTAAIHDAVAAIEPSARGELEITDAIQWLVSSG 206 Query: 240 -EILAKRIEGERYDIGS 255 ++ A + +G D G+ Sbjct: 207 ADVRASQYDGYWKDTGN 223 >emb|CAC01394.1| (AJ131360) glucose-1-phosphate thymidyltransferase [Campylobacter jejuni] Length = 307 Score = 77.6 bits (188), Expect = 2e-13 Identities = 67/246 (27%), Positives = 116/246 (46%), Gaps = 33/246 (13%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 K +I A G GTR+ P T ++ K++LPI D+P+I+Y + + A I+++LII + Sbjct: 17 KGIILAGGSGTRLYPSTLTLCKQLLPIYDKPMIYYPMSVLMLAKIKEVLII------STP 70 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 DR EL ++ +G + I Y Q++P GL ++ A+ + + Sbjct: 71 KDIDRFKEL------------FKDGSFLG--MQIQYKIQERPEGLAQGLILAQDFIQNDD 116 Query: 124 FAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELV---SRYGIIEGELIENDL 180 A++LGD+I + ++E A K+ G S+ V R+G++E + N Sbjct: 117 IALILGDNIFYGQ--GFSDILENA--KDDLKKGFASIFSYHVKDPERFGVVEMDQNGN-- 170 Query: 181 YRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNE 240 + L EK PK SN G Y + DI + P GE+++TD L N+ Sbjct: 171 --VLSLEEK--PKNPKSNHVATGLYFYNNDAIDIAKNVKPSARGELEITDVNIEYLRLNK 226 Query: 241 ILAKRI 246 + ++ + Sbjct: 227 LKSQHL 232 >pir||G75020 glucose-1-phosphate thymidylyltransferase (grad-2) PAB1115 - Pyrococcus abyssi (strain Orsay) >gi|5459119|emb|CAB50605.1| (AJ248288) glucose-1-phosphate thymidylyltransferase (graD-2) [Pyrococcus abyssi] Length = 419 Score = 77.3 bits (187), Expect = 2e-13 Identities = 68/275 (24%), Positives = 125/275 (44%), Gaps = 44/275 (16%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 KAV+ AAG G R+ P+T PK +L + ++P+I Y++E ++ Sbjct: 2 KAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILEN-------------------LD 42 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMV---DIYYVRQKKPLGLGDAILYAEKHVN 120 + D + Y+KE + +E +G+ I YV Q + G AI A+ ++ Sbjct: 43 PFVDEFIIIVKYMKE-------KIIETLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIE 95 Query: 121 GEPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDL 180 E F + GD I ++ AI+ L+ V ++ V +L S+ G +++ + Sbjct: 96 EEEFFAINGD--IYFEQEAIRGLLHVYKKTKANAALVVKKFDDL-SQLG-----MVKTEG 147 Query: 181 YRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNE 240 ++ +VEKP +A +G YI P++F+ + T GE ++TD + ++++ Sbjct: 148 GYVREIVEKPG---NVGGLANLGIYIFNPDVFEFIERTQESERGEYEITDTINLMISDGR 204 Query: 241 ILAK-RIEGERYDIGSKFGFVMAN---LKLSLRRE 271 +A G DIG + + N LK L+ + Sbjct: 205 KVAYFEYSGFWSDIGRPWDLLEVNEYILKTKLKHD 239 >gi|11497858 glucose-1-phosphate thymidylyltransferase (graD-1) [Archaeoglobus fulgidus] >gi|7448175|pir||B69280 glucose-1-phosphate thymidylyltransferase (graD-1) homolog - Archaeoglobus fulgidus >gi|2650399|gb|AAB90991.1| (AE001089) glucose-1-phosphate thymidylyltransferase (graD-1) [Archaeoglobus fulgidus] Length = 332 Score = 76.9 bits (186), Expect = 3e-13 Identities = 73/263 (27%), Positives = 124/263 (46%), Gaps = 38/263 (14%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 K +I A G TR+ PITKS K +LP+ + ++ +V E+ +K IL+ T K Sbjct: 2 KVIIMAGGYATRLWPITKSKAKPLLPVGTKRIVDHVYEKVLKFN-SPILLSTNK------ 54 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123 FE ++ GK +VE + E +R+++ LG A+ + ++ + Sbjct: 55 -----RFEEDFRKWAEGK-----DVEVVVEDT----MREEEKLGAVKALAQVVEGID-DD 99 Query: 124 FAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESV-PRELVSRYGI--IEGELIENDL 180 F V+ GD+I + + ++E+ +K +PV + V EL RYG+ +EGE+ Sbjct: 100 FLVVAGDNIFSFE---LNPIVELFRKKKSPVTALYDVGDYELAKRYGVAELEGEI----- 151 Query: 181 YRIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNE 240 ++R EK P++ S + I Y EI D+L E G + L D L L K + Sbjct: 152 --VRRFYEK--PEKPASTLVGIAIYTFPREIADLLVEYVGGNERSDNLGDFLSYLCQKMD 207 Query: 241 ILAKRIE-GERYDIGSKFGFVMA 262 + + G YD+G+ ++ A Sbjct: 208 VYGCIFDNGNWYDVGNPDSYIEA 230 >dbj|BAA77382.1| (AB020570) GDP-mannose pyrophosphorylase [Candida glabrata] Length = 361 Score = 76.5 bits (185), Expect = 3e-13 Identities = 71/259 (27%), Positives = 113/259 (43%), Gaps = 35/259 (13%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 K +I G GTR+ P+T ++PK ++ +RP+I + +E AG+ DI++ + Sbjct: 2 KGLILVGGYGTRLRPLTLTVPKPLVEFGNRPMILHQIEALANAGVTDIVLAVNCRPEVMV 61 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHV--NG 121 + L+ Y KE G V I + + +PLG + AEK + + Sbjct: 62 E------TLQKYEKEYG--------------VSITFSVETEPLGTAGPLKLAEKVLKKDN 101 Query: 122 EPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLY 181 PF VL D I + + K T V P S+YG+I ++ +L Sbjct: 102 SPFFVLNSDVICEYPFKELADFHKAHGGKGTIVATKVDEP----SKYGVIVHDIATPNL- 156 Query: 182 RIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNEI 241 I R VEK PKE N G YIL PE+ D++ P + T+ IL+ + + Sbjct: 157 -IDRFVEK--PKEFVGNRINAGLYILNPEVIDLIEMKPTSIE-----TETFPILVEQKSL 208 Query: 242 LAKRIEGERYDIGSKFGFV 260 + +EG D+G F+ Sbjct: 209 YSFDLEGFWMDVGQPKDFL 227 >pir||A72589 probable glucose-1-phosphate thymidylyltransferase APE1181 - Aeropyrum pernix (strain K1) >gi|5104853|dbj|BAA80167.1| (AP000061) 355aa long hypothetical glucose-1-phosphate thymidylyltransferase [Aeropyrum pernix] Length = 355 Score = 74.9 bits (181), Expect = 1e-12 Identities = 77/269 (28%), Positives = 126/269 (46%), Gaps = 48/269 (17%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 K +I AAG G+R+ P T S PK ++P++ +P+I Y +++ V + DI ++ G Sbjct: 3 KGLILAAGEGSRLRPFTFSRPKHLIPLLGKPIIQYAIDDLVSINVRDIGVVVG------- 55 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKH-VNGE 122 YF + E L E G Y+ QKK LG+ AI A K + Sbjct: 56 -YFGDKIK-----------EFLGEDSRFG--AKFTYIVQKKRLGIAHAIYRAIKQGFIDK 101 Query: 123 PFAVLLGDDII---ISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIEND 179 F V LGD+I+ IS+ +K E + + V R+GI + D Sbjct: 102 EFIVYLGDNILSGGISRH--VKSWGEAGSEVHILLTKVRD-----PGRFGI----AVLRD 150 Query: 180 LYRIKRLVEKPSPKEAPSNIAIIGRYI-----LIPEIFDILRETPPGRDGEIQLTDALQI 234 +I +LVEK P+E S++A++G Y+ L+ + F L+ P GE ++TD +Q Sbjct: 151 -GKILKLVEK--PQEHISDLAVVGVYMFRDPELVAKAFSTLK---PSWRGEYEITDLIQW 204 Query: 235 LLNKN-EILAKRIEGERYDIGSKFGFVMA 262 ++K ++ + G D+G+ G + A Sbjct: 205 FVDKGYKVTFSLVTGWWKDVGTYEGLLDA 233 >gi|6320148 mannose-1-phosphate guanyltransferase, GDP-mannose pyrophosphorylase; Psa1p [Saccharomyces cerevisiae] >gi|1709086|sp|P41940|MPG1_YEAST MANNOSE-1-PHOSPHATE GUANYLTRANSFERASE (ATP-MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE) (NDP-HEXOSE PYROPHOSPHORYLASE) >gi|2132332|pir||S67590 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) - yeast (Saccharomyces cerevisiae) >gi|1292898|gb|AAC49289.1| (U19608) Psa1p [Saccharomyces cerevisiae] >gi|1431053|emb|CAA98617.1| (Z74103) ORF YDL055c [Saccharomyces cerevisiae] Length = 361 Score = 73.7 bits (178), Expect = 2e-12 Identities = 70/259 (27%), Positives = 113/259 (43%), Gaps = 35/259 (13%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 K +I G GTR+ P+T ++PK ++ +RP+I + +E AG+ DI++ + Sbjct: 2 KGLILVGGYGTRLRPLTLTVPKPLVEFGNRPMILHQIEALANAGVTDIVLAVNYRPEVMV 61 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHV--NG 121 + L+ Y KE G V+I + + +PLG + AE + + Sbjct: 62 E------TLKKYEKEYG--------------VNITFSVETEPLGTAGPLKLAEDVLKKDN 101 Query: 122 EPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLY 181 PF VL D I + + K T V P S+YG+I ++ +L Sbjct: 102 SPFFVLNSDVICEYPFKELADFHKAHGGKGTIVATKVDEP----SKYGVIVHDIATPNL- 156 Query: 182 RIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNEI 241 I R VEK PKE N G YIL PE+ D++ P + E IL+ + ++ Sbjct: 157 -IDRFVEK--PKEFVGNRINAGLYILNPEVIDLIEMKPTSIEKE-----TFPILVEEKQL 208 Query: 242 LAKRIEGERYDIGSKFGFV 260 + +EG D+G F+ Sbjct: 209 YSFDLEGFWMDVGQPKDFL 227 >gb|AAA69677.1| (U24437) mannose-1-phosphate guanyltransferase [Saccharomyces cerevisiae] Length = 361 Score = 73.0 bits (176), Expect = 4e-12 Identities = 70/259 (27%), Positives = 112/259 (43%), Gaps = 35/259 (13%) Query: 4 KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63 K +I G GTR+ P+T ++PK ++ +RP+I + +E AG+ DI + + Sbjct: 2 KGLILVGGYGTRLRPLTLTVPKPLVEFGNRPMILHQIEALANAGVTDIALAVNYRPEVMV 61 Query: 64 DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHV--NG 121 + L+ Y KE G V+I + + +PLG + AE + + Sbjct: 62 E------TLKKYEKEYG--------------VNITFSVETEPLGTAGPLKLAEDVLKKDN 101 Query: 122 EPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLY 181 PF VL D I + + K T V P S+YG+I ++ +L Sbjct: 102 SPFFVLNSDVICEYPFKELADFHKAHGGKGTIVATKVDEP----SKYGVIVHDIATPNL- 156 Query: 182 RIKRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILLNKNEI 241 I R VEK PKE N G YIL PE+ D++ P + E IL+ + ++ Sbjct: 157 -IDRFVEK--PKEFVGNRINAGLYILNPEVIDLIEMKPTSIEKE-----TFPILVEEKQL 208 Query: 242 LAKRIEGERYDIGSKFGFV 260 + +EG D+G F+ Sbjct: 209 YSFDLEGFWMDVGQPKDFL 227 >emb|CAC12604.1| (AL445067) mannose-1-phosphate guanyltransferase related protein [Thermoplasma acidophilum] Length = 359 Score = 73.0 bits (176), Expect = 4e-12 Identities = 65/207 (31%), Positives = 100/207 (47%), Gaps = 30/207 (14%) Query: 1 MIRKAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKR 60 M K V+ A G GTR+ PIT S+PK ++P+ +PVI Y+++ ++GI DI+I TG Sbjct: 1 MSLKGVVMAGGKGTRLRPITYSIPKPLVPVAGKPVISYILDAFYRSGISDIIITTG---- 56 Query: 61 AIEDYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVN 120 ++ E +K G LE + +I + +K+ G + AE ++ Sbjct: 57 ---------YKFESLIK--GVLENKNSQQ------NILFSVEKEAAGTAGGVKIAENFLD 99 Query: 121 GEPFAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDL 180 + F V GD I+ + E RKN I V V + S++GI E I+ + Sbjct: 100 -DTFVVGSGD--ILIDFDIGDMIKEHQRRKNKITIAVTKV--DDPSQFGIAE---IDEEG 151 Query: 181 YRIKRLVEKPSPKEAPSNIAIIGRYIL 207 Y IKR +EKP E S+ G YI+ Sbjct: 152 Y-IKRFLEKPGKNETFSDTINAGVYIM 177 >pir||A55213 hypothetical protein 2.8, rfbB 5'-region - Shigella flexneri (strain 2a) (fragment) >gi|294895|gb|AAA53678.1| (L14842) orf2.8; putative [Shigella flexneri] Length = 129 Score = 72.2 bits (174), Expect = 7e-12 Identities = 41/112 (36%), Positives = 61/112 (53%), Gaps = 1/112 (0%) Query: 177 ENDLYRIKRLVEKPS-PKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQIL 235 E + RI +EKP P+ S+I +GRY+L +I+ L T PG G IQLTDA+ L Sbjct: 18 EGKVSRIVEFIEKPDQPQTLDSDIMAVGRYVLSADIWPELERTQPGAWGRIQLTDAIAEL 77 Query: 236 LNKNEILAKRIEGERYDIGSKFGFVMANLKLSLRREELRNEVLKYLKSILKE 287 K + A + G+ YD G K G++ A +K LR + + K ++ +L E Sbjct: 78 AKKQSVDAMLMTGDSYDCGKKMGYMQAFVKYGLRNLKEGAKFRKGIEKLLSE 129 >dbj|BAA15884.1| (D90841) UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) (UDP-glucose pyrophosphorylase) (UDPGP) (a-d-glucosyl-1-phosphate uridylyltransferase) (Uridine diphosphoglucose pyrophosphorylase). [Escherichia coli] Length = 163 Score = 72.2 bits (174), Expect = 7e-12 Identities = 41/112 (36%), Positives = 61/112 (53%), Gaps = 1/112 (0%) Query: 177 ENDLYRIKRLVEKPS-PKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQIL 235 E + RI +EKP P+ S+I +GRY+L +I+ L T PG G IQLTDA+ L Sbjct: 52 EGKVSRIVEFIEKPDQPQTLDSDIMAVGRYVLSADIWPELERTQPGAWGRIQLTDAIAEL 111 Query: 236 LNKNEILAKRIEGERYDIGSKFGFVMANLKLSLRREELRNEVLKYLKSILKE 287 K + A + G+ YD G K G++ A +K LR + + K ++ +L E Sbjct: 112 AKKQSVDAMLMTGDSYDCGKKMGYMQAFVKYGLRNLKEGAKFRKGIEKLLSE 163 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.319 0.142 0.388 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 104942415 Number of Sequences: 2977 Number of extensions: 4735861 Number of successful extensions: 14193 Number of sequences better than 1.0e-10: 186 Number of HSP's better than 0.0 without gapping: 73 Number of HSP's successfully gapped in prelim test: 116 Number of HSP's that attempted gapping in prelim test: 13761 Number of HSP's gapped (non-prelim): 212 length of query: 291 length of database: 189,106,746 effective HSP length: 57 effective length of query: 234 effective length of database: 154,992,987 effective search space: 36268358958 effective search space used: 36268358958 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.7 bits) S2: 165 (68.7 bits)