BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0775 (PAB0775) DE:NADH-DEPENDENT DEHYDROGENASE HOMOLOG.
(315 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||E75096 NADH-dependent dehydrogenase homolog. PAB0775 - Pyro... 615 e-175
pir||H69216 3-chlorobenzoate-3,4-dioxygenase dyhydrogenase relat... 266 2e-70
pir||S76068 hypothetical protein - Synechocystis sp. (strain PCC... 215 5e-55
sp|P40332|YISS_BACSU HYPOTHETICAL 37.5 KD PROTEIN IN DEGA-NPRB I... 136 2e-31
pir||A75025 NADH-dependent dyhydrogenase related protein PAB1138... 132 6e-30
pir||D71201 hypothetical protein PH1881 - Pyrococcus horikoshii ... 130 2e-29
pir||D72381 dehydrogenase - Thermotoga maritima (strain MSB8) >g... 129 3e-29
gb|AAK43117.1| Dehydrogenase, putative [Sulfolobus solfataricus] 129 3e-29
dbj|BAB04967.1| (AP001511) NADH-dependent dyhydrogenase [Bacillu... 129 5e-29
sp|O05389|YRBE_BACSU HYPOTHETICAL 37.8 KDA PROTEIN IN CSBX-NADA ... 124 1e-27
pir||B72359 lipopolysaccharide biosynthesis protein BplA - Therm... 123 2e-27
pir||B75025 NADH-dependent dyhydrogenase related protein PAB1139... 122 7e-27
pir||E71201 probable glucose-fructose oxidoreductase - Pyrococcu... 121 9e-27
pir||A81396 hypothetical protein Cj0504c [imported] - Campylobac... 115 5e-25
gb|AAK43113.1| Dehydrogenase, putative [Sulfolobus solfataricus] 108 7e-23
dbj|BAB05884.1| (AP001514) unknown conserved protein [Bacillus h... 107 2e-22
pir||A83617 probable oxidoreductase PA0237 [imported] - Pseudomo... 102 4e-21
dbj|BAB05939.1| (AP001514) dehydrogenase [Bacillus halodurans] 102 5e-21
gb|AAK43149.1| Dehydrogenase, putative [Sulfolobus solfataricus] 98 2e-19
gb|AAC31183.1| (AF076240) putative NADH-inositol dehydrogenase M... 96 5e-19
emb|CAB88961.1| (AL353864) putative oxidoreductase. [Streptomyce... 94 1e-18
sp|P49307|MOCA_RHIME RHIZOPINE CATABOLISM PROTEIN MOCA >gi|21208... 94 3e-18
pir||B75475 glucose-fructose oxidoreductase - Deinococcus radiod... 93 3e-18
dbj|BAB04429.1| (AP001509) unknown conserved protein [Bacillus h... 92 8e-18
gb|AAC23913.1| (AF039207) NADH-dependent dehydrogenase homolog [... 92 1e-17
emb|CAB60174.1| (AL132824) putative dehydrogenase [Streptomyces ... 91 2e-17
sp|O68965|MI2D_RHIME MYO-INOSITOL 2-DEHYDROGENASE >gi|3088561|gb... 89 9e-17
sp|Q05184|PHT4_PSEPU PUTATIVE 4,5,-DIHYDROXYPHTHALATE DEHYDROGEN... 85 1e-15
sp|Q54728|YJHC_STRPN HYPOTHETICAL PROTEIN IN NANB 3'REGION (ORF-... 85 1e-15
emb|CAC11912.1| (AL445065) hypothetical protein [Thermoplasma ac... 83 5e-15
gb|AAG09709.1|AF218837_4 (AF218837) unknown [Pasteurella multocida] 82 6e-15
sp|P09400|STRI_STRGR STREPTOMYCIN BIOSYNTHESIS PROTEIN STRI >gi|... 82 6e-15
pir||S70672 dehydrogenase homolog - Bordetella pertussis >gi|992... 82 6e-15
dbj|BAB05940.1| (AP001514) unknown conserved protein [Bacillus h... 82 8e-15
dbj|BAB06035.1| (AP001515) myo-inositol 2-dehydrogenase [Bacillu... 82 8e-15
gb|AAD51832.1|AF175299_7 (AF175299) ThuB [Sinorhizobium meliloti] 81 1e-14
emb|CAB88965.1| (AL353864) putative oxidoreductase. [Streptomyce... 79 6e-14
gb|AAD03557.1| (AF095748) phthalate dihydrodiol dehydrogenase [B... 79 7e-14
sp|P26935|MI2D_BACSU MYO-INOSITOL 2-DEHYDROGENASE >gi|80338|pir|... 77 2e-13
gb|AAC01706.1| (AF040570) unknown [Amycolatopsis mediterranei] 77 3e-13
emb|CAC11395.1| (AL445063) glucose-fructose oxidoreductase relat... 77 3e-13
pir||T36464 probable oxidoreductase - Streptomyces coelicolor >g... 76 5e-13
pir||A71443 probable inositol 2-dehydrogenase - Arabidopsis thal... 76 5e-13
gb|AAC71791.1| (M77665) qutH [Aspergillus nidulans] 75 1e-12
emb|CAC12307.1| (AL445066) glucose-fructose oxidoreductase relat... 75 1e-12
pir||A69834 conserved hypothetical protein yhjJ - Bacillus subti... 74 2e-12
emb|CAB02496.1| (Z80356) glucose-fructose oxidoreductase [Zymomo... 73 3e-12
pdb|1OFG|A Chain A, Glucose-Fructose Oxidoreductase >gi|2098324|... 73 3e-12
sp|Q07982|GFO_ZYMMO GLUCOSE--FRUCTOSE OXIDOREDUCTASE PRECURSOR (... 73 5e-12
pir||A72379 hypothetical protein TM0425 - Thermotoga maritima (s... 73 5e-12
pir||S56505 hypothetical 41.9K protein (leuX-fecE intergenic reg... 72 7e-12
sp|P39353|YJHC_ECOLI HYPOTHETICAL 41.4 KD PROTEIN IN LEUX-FECE I... 72 7e-12
pir||T50594 probable oxidoreductase [imported] - Streptomyces co... 72 7e-12
sp|P77503|YCJS_ECOLI HYPOTHETICAL 38.7 KD PROTEIN IN PSPE-OMPG I... 72 9e-12
pir||G72391 conserved hypothetical protein - Thermotoga maritima... 71 2e-11
gb|AAK43115.1| Dehydrogenase, putative [Sulfolobus solfataricus] 71 2e-11
dbj|BAA83485.1| (AB021928) dimeric dihydrodiol dehydrogenase [Or... 70 3e-11
dbj|BAB07562.1| (AP001520) oxidoreductase [Bacillus halodurans] 70 4e-11
pir||A82502 oxidoreductase, Gfo/Idh/MocA family VCA0099 [importe... 69 5e-11
dbj|BAA83486.1| (AB021929) dimeric dihydrodiol dehydrogenase [Su... 69 8e-11
>pir||E75096 NADH-dependent dehydrogenase homolog. PAB0775 - Pyrococcus abyssi
(strain Orsay) >gi|5458586|emb|CAB50074.1| (AJ248286)
NADH-DEPENDENT DEHYDROGENASE HOMOLOG. [Pyrococcus
abyssi]
Length = 315
Score = 615 bits (1569), Expect = e-175
Identities = 315/315 (100%), Positives = 315/315 (100%)
Query: 1 MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELI 60
MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELI
Sbjct: 1 MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELI 60
Query: 61 KEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMVG 120
KEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMVG
Sbjct: 61 KEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMVG 120
Query: 121 HVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTRISDVGVIIDLAVHDIDVMSFLT 180
HVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTRISDVGVIIDLAVHDIDVMSFLT
Sbjct: 121 HVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTRISDVGVIIDLAVHDIDVMSFLT 180
Query: 181 TSRVIEVYAKARNVKHPAKVEDYALILLSFENGANGIIETNRLTPHKTRTLNVVGTEGIA 240
TSRVIEVYAKARNVKHPAKVEDYALILLSFENGANGIIETNRLTPHKTRTLNVVGTEGIA
Sbjct: 181 TSRVIEVYAKARNVKHPAKVEDYALILLSFENGANGIIETNRLTPHKTRTLNVVGTEGIA 240
Query: 241 YLDYINQELTLYNEEWIYKAKINKEEPLKLEIEHFLECVKEGKKPLVGGEEGLHALKVAV 300
YLDYINQELTLYNEEWIYKAKINKEEPLKLEIEHFLECVKEGKKPLVGGEEGLHALKVAV
Sbjct: 241 YLDYINQELTLYNEEWIYKAKINKEEPLKLEIEHFLECVKEGKKPLVGGEEGLHALKVAV 300
Query: 301 KALESSKKDEVVRVS 315
KALESSKKDEVVRVS
Sbjct: 301 KALESSKKDEVVRVS 315
>pir||H69216 3-chlorobenzoate-3,4-dioxygenase dyhydrogenase related protein -
Methanobacterium thermoautotrophicum (strain Delta H)
>gi|2621968|gb|AAB85373.1| (AE000863)
3-chlorobenzoate-3,4-dioxygenase dyhydrogenase related
protein [Methanobacterium thermoautotrophicum]
Length = 318
Score = 266 bits (673), Expect = 2e-70
Identities = 139/316 (43%), Positives = 208/316 (64%), Gaps = 5/316 (1%)
Query: 1 MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELI 60
+ VGV+GVG MGY+HAR+Y L L+ V+DI ++VA + T + DY L+
Sbjct: 4 INVGVIGVGAMGYNHARVYYRLKN---ANLMAVSDIMKGTLQKVANKYDTVGYVDYENLL 60
Query: 61 K-EGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMV 119
+ ++ VS+ VPT+ H V MD +E++ VLVEKPIA ++E A++++K A+K + L
Sbjct: 61 EIPEIEVVSVCVPTTHHYNVVMDALEHDKHVLVEKPIAFTLEEAEDMVKTARKKGLKLGT 120
Query: 120 GHVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTRISDVGVIIDLAVHDIDVMSFL 179
GHVERFNPAV K KE IE ++G++V+ +AKRVGP RI DVGV IDLA+HD+DVM +L
Sbjct: 121 GHVERFNPAVQKAKELIENDVIGDVVSASAKRVGPFPPRIKDVGVTIDLAIHDLDVMHYL 180
Query: 180 TTSRVIEVYAKARNVKHPAKVEDYALILLSFENGANGIIETNRLTPHKTRTLNVVGTEGI 239
+ V EVYA ++ + ED+A I+ F++G GI+E N LTP+K R L + GT+GI
Sbjct: 181 FSEPVAEVYAVMGSILEKCEYEDHAEIMTKFKSGITGILEVNWLTPYKRRKLAITGTDGI 240
Query: 240 AYLDYINQELTLYNEEWIYKAKINKEEPLKLEIEHFLECVKEGKKPLVGGEEGLHALKVA 299
+DYI+Q L +Y ++ I EEPLK EI+ FL V ++P + GE+G++AL+
Sbjct: 241 INVDYIDQRLDVYG-KFAQDVDIKHEEPLKNEIKSFLMSVINDEEPEITGEDGIYALRTV 299
Query: 300 VKALESSKKDEVVRVS 315
+ A++S+++ V+V+
Sbjct: 300 LAAMKSAREHRPVKVN 315
>pir||S76068 hypothetical protein - Synechocystis sp. (strain PCC 6803)
>gi|1001423|dbj|BAA10046.1| (D63999) hypothetical
protein [Synechocystis sp.]
Length = 364
Score = 215 bits (542), Expect = 5e-55
Identities = 117/316 (37%), Positives = 183/316 (57%), Gaps = 25/316 (7%)
Query: 1 MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELI 60
+R+GV+GVG MG HH R+ S L K+ VE +G+AD+N ER + A ++ F+DY+E++
Sbjct: 24 IRIGVIGVGNMGQHHTRVLS-LMKD--VEFVGIADVNVERGLDTASKYRVHFFEDYQEML 80
Query: 61 KEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMVG 120
VDAV +AVPT LH +V M+ ++N V L+EKPIA SI A+ ++ AA N +L VG
Sbjct: 81 PH-VDAVCVAVPTRLHHDVGMNCLQNNVHTLIEKPIAASIAEAESLVNAAADANCILQVG 139
Query: 121 HVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTRISDVGVIIDLAVHDIDVMSFLT 180
H+ERFNPA L+L + ++ E++ + A R+ P R +DV V++DL +HDID++ L
Sbjct: 140 HIERFNPAFLELTKILK---TEELLAIEAHRMSPYSQRANDVSVVLDLMIHDIDLLLELV 196
Query: 181 TSRVIEVYAKARNVKHPAKVEDYALILLSFENGANGIIETNRLTPHKTRTLNVVGTEGIA 240
S V+++ A + DY L F +G + +++T K R++ +
Sbjct: 197 GSEVVKLSASGSRASGSGYL-DYVTATLGFSSGIVATLTASKVTHRKIRSIAAHCKNSLT 255
Query: 241 YLDYINQELTLYNE---EW--------------IYKAKINKEEPLKLEIEHFLECVKEGK 283
D++N E+ ++ + +W I K + EPL E+EHF+ CV+ G
Sbjct: 256 EADFLNNEILIHRQTTADWSADYGQVLYRQDGLIEKVYTSNIEPLHAELEHFIHCVRGGD 315
Query: 284 KPLVGGEEGLHALKVA 299
+P VGGE+ L ALK+A
Sbjct: 316 QPSVGGEQALKALKLA 331
>sp|P40332|YISS_BACSU HYPOTHETICAL 37.5 KD PROTEIN IN DEGA-NPRB INTERGENIC REGION
>gi|7429794|pir||B69838 myo-inositol 2-dehydrogenase
homolog yisS - Bacillus subtilis
>gi|1934841|emb|CAB07962.1| (Z93940) unknown [Bacillus
subtilis] >gi|2145385|emb|CAA70648.1| (Y09476) YisS
[Bacillus subtilis] >gi|2633420|emb|CAB12924.1| (Z99109)
alternate gene name: yuxD, yucG~similar to myo-inositol
2-dehydrogenase [Bacillus subtilis]
Length = 342
Score = 136 bits (340), Expect = 2e-31
Identities = 96/332 (28%), Positives = 166/332 (49%), Gaps = 21/332 (6%)
Query: 1 MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKD--YRE 58
+R V+G+G++GY+HA+ + + +L+ V D RA++VA + + Y
Sbjct: 5 VRCAVLGLGRLGYYHAK--NLVTSVPGAKLVCVGDPLKGRAEQVARELGIEKWSEDPYEV 62
Query: 59 LIKEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLM 118
L G+DAV I PTS H ++ + EN + VEKP+ S+E ++ + K+ V+
Sbjct: 63 LEDPGIDAVIIVTPTSTHGDMIIKAAENGKQIFVEKPLTLSLEESKAASEKVKETGVICQ 122
Query: 119 VGHVERFNPAVLKLKETIERGMLGEIV---TMTAKRVGPMVTRIS-DVGVIIDLAVHDID 174
VG + RF+PA K I+ G +G+ + T + P I G+ ID ++HD D
Sbjct: 123 VGFMRRFDPAYADAKRRIDAGEIGKPIYYKGFTRDQGAPPAEFIKHSGGIFIDCSIHDYD 182
Query: 175 VMSFLTTSRVIEVYAKARNVKHPAKVE----DYALILLSFENGANGIIETNRLTP--HKT 228
+ +L + + V R + +P + D AL + F++GA G +E +R +P H
Sbjct: 183 IARYLLGAEITSVSGHGRILNNPFMEQYGDVDQALTYIEFDSGAAGDVEASRTSPYGHDI 242
Query: 229 RTLNVVGTEGIAYLDYI-NQELTLYNE-----EWIYKAKINKEEPLKLEIEHFLECVKEG 282
R V+GTEG ++ + +Q +T+ + + I + E LE++HF ECV+ G
Sbjct: 243 RA-EVIGTEGSIFIGTLRHQHVTILSAKGSSFDIIPDFQTRFHEAYCLELQHFAECVRNG 301
Query: 283 KKPLVGGEEGLHALKVAVKALESSKKDEVVRV 314
K P+V + L+V + A S + V++
Sbjct: 302 KTPIVTDIDATINLEVGIAATNSFRNGMPVQL 333
>pir||A75025 NADH-dependent dyhydrogenase related protein PAB1138 - Pyrococcus
abyssi (strain Orsay) >gi|5459153|emb|CAB50639.1|
(AJ248288) NADH-dependent DYHYDROGENASE RELATED PROTEIN
[Pyrococcus abyssi]
Length = 341
Score = 132 bits (328), Expect = 6e-30
Identities = 96/347 (27%), Positives = 165/347 (46%), Gaps = 46/347 (13%)
Query: 1 MRVGVVGVGKM-GYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYREL 59
++VG++G G + H L KV + V DI+ E A++ + + F E
Sbjct: 5 LKVGIIGCGNIFNLAHKPALKSLRTIAKV--VAVMDIDEEAARKAGKELNAKVFTSLDEF 62
Query: 60 IKEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMV 119
+++ ++ V I PT H E+ ++ ++ V+VEKPIA ++E A+++IK A+ + L V
Sbjct: 63 LEQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFV 122
Query: 120 GHVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTRISDV----------------- 162
GHV RF+ +++K+ I+ ++ + PM R +V
Sbjct: 123 GHVRRFDKRWIQIKDIIK-----------SRNILPMQIRKIEVQHLPFPADYWYWDESKS 171
Query: 163 -GVIIDLAVHDIDVMSFLTTSRVIEVYAKARNVKHPAKV---EDYALILLSFENGANGII 218
GVI+DL VH D + + S IEV+A + ++ A+V D+ ++ + FE G GI
Sbjct: 172 GGVIVDLGVHVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIG 231
Query: 219 ETNRLTPHKTR------TLNVVGTEG-IAYLDYINQELTLYNEEW----IYKAKINKEEP 267
E + P + L+++G G I Y + + + +
Sbjct: 232 EVSWSYPMPPKYGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPRFSPMLSTFPQA 291
Query: 268 LKLEIEHFLECVKEGKKPLVGGEEGLHALKVAVKALESSKKDEVVRV 314
+ E+ HF EC+K +P+V ++ L ALK+A KA ES KK E V+V
Sbjct: 292 FEAELRHFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKV 338
>pir||D71201 hypothetical protein PH1881 - Pyrococcus horikoshii
>gi|3258320|dbj|BAA31003.1| (AP000007) 371aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 371
Score = 130 bits (323), Expect = 2e-29
Identities = 97/336 (28%), Positives = 159/336 (46%), Gaps = 24/336 (7%)
Query: 1 MRVGVVGVGKM-GYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYREL 59
++VGV+G G + H L KV + V DIN E AK+ + + F E
Sbjct: 35 LKVGVIGCGNIFNLAHKPALRSLRTIAKV--VAVMDINEEAAKKAGKELNAKVFTSLDEF 92
Query: 60 IKEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMV 119
+++ +D V + PT H E+ + ++ V+VEKPIA + E A+++IK A++ + L V
Sbjct: 93 LEQDMDVVEVLTPTYTHAEIAIKALKAGKHVIVEKPIALTSEEAEKMIKEAEEQGLKLFV 152
Query: 120 GHVERFNPAVLKLKETIE-RGMLGEIVTMTAKRVGPMVT------RISDVGVIIDLAVHD 172
GHV RF+ ++KE I+ R +L + + P GVIIDL VH
Sbjct: 153 GHVRRFDKRWTQIKEVIKTRNILPMQIRKIEVQHLPFPADYWYWDESKSGGVIIDLGVHV 212
Query: 173 IDVMSFLTTSRVIEVYAKARNVKHPAKVE---DYALILLSFENGANGIIETNRLTPHKTR 229
D + + S +EV+A + ++ A+V D+ ++ + FE GI E + P +
Sbjct: 213 TDFLRWFFESEPVEVFAVGKAIRGEARVNKTYDHVVMFIKFEGNKTGIGEVSWSYPMTPK 272
Query: 230 ------TLNVVGTEG-IAYLDYINQELTLYNEEW----IYKAKINKEEPLKLEIEHFLEC 278
L+++G G I Y + + + + + E+ HF EC
Sbjct: 273 YGVFYHHLDIIGKNGRIRYTPLDTPVVGVIKSSFEMPRFSPMLSTFPQAFEAELRHFFEC 332
Query: 279 VKEGKKPLVGGEEGLHALKVAVKALESSKKDEVVRV 314
+K +P+V + L AL++A KA ES KK E V+V
Sbjct: 333 IKSNCEPVVTARDALIALQIAEKARESIKKGEPVKV 368
>pir||D72381 dehydrogenase - Thermotoga maritima (strain MSB8)
>gi|4980919|gb|AAD35499.1|AE001720_13 (AE001720)
dehydrogenase [Thermotoga maritima]
Length = 334
Score = 129 bits (322), Expect = 3e-29
Identities = 91/333 (27%), Positives = 172/333 (51%), Gaps = 23/333 (6%)
Query: 1 MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKT-RAFKDYREL 59
MR+GV+G+G++G HA L L ++D+ +R +E+ E +A+KD EL
Sbjct: 1 MRIGVIGLGRIGTIHAE---NLKMIDDAILYAISDVREDRLREMKEKLGVEKAYKDPHEL 57
Query: 60 IKE-GVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLM 118
I++ VDAV + T+ H E+ + + + V EKP++ ++ +I+ KK +V+L
Sbjct: 58 IEDPNVDAVLVCSSTNTHSELVIACAKAKKHVFCEKPLSLNLADVDRMIEETKKADVILF 117
Query: 119 VGHVERFNPAVLKLKETIERGMLGE--IVTMTAKRVGPM---VTRISDVGVIIDLAVHDI 173
G RF+ KLKE +E G +G+ ++ +T++ P R+S G+ +D+ +HD
Sbjct: 118 TGFNRRFDRNFKKLKEAVENGTIGKPHVLRITSRDPAPPPLDYIRVSG-GIFLDMTIHDF 176
Query: 174 DVMSFLTTSRVIEVYAKARNVKH----PAKVEDYALILLSFENGANGIIETNRLTPH-KT 228
D+ ++ V EV+A + A D A+++L F++GA G+I+ +R +
Sbjct: 177 DMARYIMGEEVEEVFADGSVLVDEEIGKAGDVDTAVVVLRFKSGALGVIDNSRRAVYGYD 236
Query: 229 RTLNVVGTEGIAYLDYINQELTLYNEE-------WIYKAKINKEEPLKLEIEHFLECVKE 281
+ + V G++G + D + + + +E ++Y + E++ F++ VK
Sbjct: 237 QRIEVFGSKGRIFADNVRETTVVLTDEQGDRGSRYLYFFLERYRDSYLEELKTFIKNVKS 296
Query: 282 GKKPLVGGEEGLHALKVAVKALESSKKDEVVRV 314
G+ P V GE+G AL + A +S ++ V++
Sbjct: 297 GEPPAVSGEDGKMALLLGYAAKKSLEEKRSVKL 329
>gb|AAK43117.1| Dehydrogenase, putative [Sulfolobus solfataricus]
Length = 355
Score = 129 bits (322), Expect = 3e-29
Identities = 97/353 (27%), Positives = 174/353 (48%), Gaps = 39/353 (11%)
Query: 1 MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELI 60
+R G++GVG G + + + + KVE++ VAD+ ER +EV+ F + + DY E++
Sbjct: 3 IRYGIIGVGGHGKNR-HLIPLIKLKNKVEIVAVADVKKERCEEVSSQFNIKCYLDYMEMV 61
Query: 61 -KEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMV 119
KE ++AVSI PT LH + ++ + V+VLV+KP+ ++E +E++ A+ + LMV
Sbjct: 62 EKESLNAVSIVTPTGLHSRIAINVLNKGVNVLVDKPLGSNLEEVKEVVNTARNKGLKLMV 121
Query: 120 GHVERFNPAVLKLKETIERGMLGEIVT----MTAKRVGPMVTRISDV------GVIIDLA 169
G+ RF+PA+ KE I G+LGE + +R P + D G ++D+
Sbjct: 122 GYWSRFSPALQYGKEIIHNGLLGEPYVAYGYLVRRRGIPGIPTFIDKTLSGGRGALLDIG 181
Query: 170 VHDID-VMSFLTTSRVI----EVYAKARNVKHPAK------------VEDYALILLSFEN 212
+ ID ++S L + I +VY K NVK K ++DYA+ L+ E
Sbjct: 182 CYLIDNLLSLLKFRKPISVMGKVYTKFGNVKEEVKFNWGSWDPENFSLDDYAVGLVKLEG 241
Query: 213 GANGIIE----TNRLTPHKTRTLNVV----GTEGIAYLDYINQELTLYNEEWIYKAK--I 262
+ I+E N + + ++ G EG + ++ E ++ K +
Sbjct: 242 DVSLILEVGWSANVSHVEEKSYVRILGDKGGIEGSGHEAIVDISFHSRTENFLTDTKPVL 301
Query: 263 NKEEPLKLEIEHFLECVKEGKKPLVGGEEGLHALKVAVKALESSKKDEVVRVS 315
K +P I F++ + ++P + GEE + + +SS +D+ V++S
Sbjct: 302 RKVDPYFEMINAFVDSILTDREPPITGEESVTLHSIIDGIYKSSTEDKEVKIS 354
>dbj|BAB04967.1| (AP001511) NADH-dependent dyhydrogenase [Bacillus halodurans]
Length = 340
Score = 129 bits (320), Expect = 5e-29
Identities = 94/340 (27%), Positives = 162/340 (47%), Gaps = 29/340 (8%)
Query: 1 MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELI 60
+RV V+G G + H R E + ++ V D ERAK+VA+ + A+ D+ +L+
Sbjct: 4 LRVAVIGCGSIAQH--RHLPEYEQNPHTTIVAVCDPVEERAKKVAKLYGAIAYTDHMQLL 61
Query: 61 -KEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMV 119
KE +D VS+ P + H +++D ++ VL EKP+A S E + +IKAA++ + LM+
Sbjct: 62 EKEEIDLVSVCTPNAYHAPISIDALKAGTHVLCEKPMATSAEECEAMIKAAEEAGMCLMI 121
Query: 120 GHVERFNPAVLKLKETIERGMLGEIVTM--TAKRVGPMVTRISD------------VGVI 165
GH +RF + K ++ I G +G+I + T GP + +G +
Sbjct: 122 GHNQRFVSSHEKARQLIATGDIGKIYSFRTTFGHGGPEGWSVDGENSWFFKKDQAFIGAM 181
Query: 166 IDLAVHDIDVMSFLTTSRVIEVYAKARNVKHPAKVEDYALILLSFENGANGIIETN-RLT 224
DL VH D++ +L V+EV A V+D A+ +L E+G G + +
Sbjct: 182 GDLGVHKADLLRYLLGEEVVEVGAFVTTSAKQGDVDDNAVAILKTESGIVGTLTASWSYV 241
Query: 225 PHKTRTLNVVGTEGIAYLD----------YINQELTLYNEEWIYKAKINKEEPLKLEIEH 274
+ + + G I L+ Y N E Y I + ++ I H
Sbjct: 242 AKEDNSTILYGENAILRLEDDPHYSLIVHYKNGETVKYELGQIQSNDEGGQTDSRV-IAH 300
Query: 275 FLECVKEGKKPLVGGEEGLHALKVAVKALESSKKDEVVRV 314
F+ V EGK+P + G+EG +L + + A+E+S+ +++
Sbjct: 301 FVNSVLEGKEPPISGKEGYASLNIILAAMEASRTGRTIKL 340
>sp|O05389|YRBE_BACSU HYPOTHETICAL 37.8 KDA PROTEIN IN CSBX-NADA INTERGENIC REGION (ORF1)
>gi|7429795|pir||D69972 opine catabolism homolog yrbE -
Bacillus subtilis >gi|2635242|emb|CAB14737.1| (Z99118)
similar to opine catabolism [Bacillus subtilis]
>gi|6977802|emb|CAB75327.1| (Y15896) hypothetical
protein [Bacillus subtilis]
Length = 341
Score = 124 bits (309), Expect = 1e-27
Identities = 88/320 (27%), Positives = 161/320 (49%), Gaps = 21/320 (6%)
Query: 4 GVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAF-KDYRELIKE 62
G++G G++G H + S + +++ ++DI R K A++ + DYR+L+ +
Sbjct: 8 GIIGAGRIGKLHVQNISRIPH---MKIKAISDIQASRIKSWADSHQIEYITSDYRDLLHD 64
Query: 63 -GVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMVGH 121
+DA+ I PT++H ++ + E + + EKP++ S++ E + A +K V L VG
Sbjct: 65 PDIDAIFICSPTAVHAQMIKEAAEAKKHIFCEKPVSFSLDETSEALAAVRKHGVTLQVGF 124
Query: 122 VERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTRISDV----GVIIDLAVHDIDVMS 177
RF+P K+K +E G +G + P I V G+ +D+++HD D+
Sbjct: 125 NRRFDPHFKKIKTIVENGEIGTPHLLKITSRDPEPPNIDYVRTSGGLFMDMSIHDFDMAR 184
Query: 178 FLTTSRVIEVYAKARNVKHPAKVE----DYALILLSFENGANGIIETNRLTPH-KTRTLN 232
++ S V EVYAK + +P+ E D A+I L+FENGA +I+ +R + + +
Sbjct: 185 YIMGSEVTEVYAKGAALVNPSFAELGDIDTAVITLTFENGAMAVIDNSRQAVYGYDQRVE 244
Query: 233 VVGTEGIAYLDYIN-QELTLYNEEWIYKAKIN------KEEPLKLEIEHFLECVKEGKKP 285
V GT+G A D + + +++ K K + ++ + EI F E + ++
Sbjct: 245 VFGTKGSAAADNSRPTTVEVSTADFVMKDKPHFFFLERYKDSYEEEILRFAEAIGTNQET 304
Query: 286 LVGGEEGLHALKVAVKALES 305
G +GL A ++A A +S
Sbjct: 305 PCTGNDGLQAGRIARAAQQS 324
>pir||B72359 lipopolysaccharide biosynthesis protein BplA - Thermotoga maritima
(strain MSB8) >gi|4981103|gb|AAD35670.1|AE001733_7
(AE001733) lipopolysaccharide biosynthesis protein BplA
[Thermotoga maritima]
Length = 360
Score = 123 bits (307), Expect = 2e-27
Identities = 92/330 (27%), Positives = 160/330 (47%), Gaps = 31/330 (9%)
Query: 1 MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFK------ 54
+R+ +VG G++G + + + + E + V D+ ERA AE F+ +
Sbjct: 3 LRIALVGCGRIG-QKKHVPALIETQDLFETVAVCDLVEERANRAAEHFEKSGLRRPETMT 61
Query: 55 DYRELIK-EGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKM 113
+YREL+K E VD +SIA + H ++TM+ +E VLVEKP+A S + E+++ +K+
Sbjct: 62 NYRELLKREDVDVISIATESGKHYQITMEALEAGKHVLVEKPMALSTKHMNEMVELSKQK 121
Query: 114 NVVLMVGHVERFNPAVLKLKETIERGMLGEIVTMTA-----------KRVGPMVTRISDV 162
N+ L V RFNP V ++++ ++ G G+I + K+ T D
Sbjct: 122 NLKLGVFFQNRFNPPVQEVRKKLDSGAFGKIFYASVAVRWNRNEDYYKQASWRGTWEMDG 181
Query: 163 GVIIDLAVHDIDVMSFLTTSRVIEVYAKARNVKHP-AKVEDYALILLSFENGANGIIE-T 220
GV+++ + H ID++ + + E+Y N HP + ED ++ F+ G G+IE T
Sbjct: 182 GVLMNQSTHAIDLLQWFLGGEIEEIYGHIANTNHPYIEAEDEGFAIVKFKGGKTGLIEAT 241
Query: 221 NRLTPHK-TRTLNVVGTEGIAYLD--YINQELTLYNEEWIYKAKINKEEP-------LKL 270
+ + P TL + G +G + +N+ LT E +N +P K
Sbjct: 242 SNVFPRNLEETLAIFGEKGTVVIGGIAVNRILTWRFEGEEGHPFMNLPDPDTVYGDSHKY 301
Query: 271 EIEHFLECVKEGKKPLVGGEEGLHALKVAV 300
F E V +KP + GE+G A+++ +
Sbjct: 302 VYRDFYEAVTNDRKPYISGEDGKKAVEIVL 331
>pir||B75025 NADH-dependent dyhydrogenase related protein PAB1139 - Pyrococcus
abyssi (strain Orsay) >gi|5459154|emb|CAB50640.1|
(AJ248288) NADH-dependent DYHYDROGENASE RELATED PROTEIN
[Pyrococcus abyssi]
Length = 335
Score = 122 bits (302), Expect = 7e-27
Identities = 98/333 (29%), Positives = 161/333 (47%), Gaps = 29/333 (8%)
Query: 7 GVGKMGYHHARIYSELAKEGK-VELIGVAD--INFERAKEVAETFKTRAFKDYRELIK-E 62
GV + HA Y+ + + +L+ ++ N AK A+ + + ++DY +L++ E
Sbjct: 5 GVISYAHPHALRYAATIRANRRAKLVAISGDGANSGLAKIEAKKYGAKFYQDYEKLLRDE 64
Query: 63 GVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMVGHV 122
V+AV IA+ T H+EV + E +L+EKPIA ++E +EI+KAA+K V LMV
Sbjct: 65 SVEAVYIAIETYRHKEVAIRAAEEGKDILLEKPIALTLEDGKEIVKAARKAGVKLMVPFN 124
Query: 123 ERFNPAVLKLKETIERGMLGE---IVTMTAKRVGPMVTRISDV-----------GVIIDL 168
RF + K KE IE+G +G+ I T++ PM D G +D
Sbjct: 125 PRFTQPLQKAKEMIEKGEIGKLEYIYTISEYVKPPMFLEGIDTSWFFDIKKSGGGGFMDT 184
Query: 169 AVHDIDVMSFLTTSRVIEVYAKARNVKHPAKVEDYALILLSFENGANGIIETNRLTPH-- 226
A H ID + +LT S I VYA +V+D L+ F+NG ++ P
Sbjct: 185 APHGIDSLFWLTESEPIRVYADIGPKIWGFQVDDIGTALIEFKNGVIAVLTAGWANPKGY 244
Query: 227 ---KTRTLNVVGTEGIAYLDYINQELTLYNE--EWIYKAKINKEEPLKLEIEHFLECVKE 281
+VG +G + + T+Y + E I+ + + E + F++ +++
Sbjct: 245 PYGLEIKYYIVGDDGFLDIRSAYPDFTVYQDKTEKIFWERADVEG----IVNAFIDAIQQ 300
Query: 282 GKKPLVGGEEGLHALKVAVKALESSKKDEVVRV 314
K+P + GE+ L L V + A ESSK + V+V
Sbjct: 301 DKEPPITGEDALKNLAVVLAAYESSKTGKAVKV 333
>pir||E71201 probable glucose-fructose oxidoreductase - Pyrococcus horikoshii
>gi|3258321|dbj|BAA31004.1| (AP000007) 335aa long
hypothetical glucose-fructose oxidoreductase [Pyrococcus
horikoshii]
Length = 335
Score = 121 bits (301), Expect = 9e-27
Identities = 94/326 (28%), Positives = 160/326 (48%), Gaps = 28/326 (8%)
Query: 14 HHARIYSELAKEGKVELIGVAD--INFERAKEVAETFKTRAFKDYRELIKE-GVDAVSIA 70
H R S + + +L+ ++ N AK A+ + + +++Y +L+K+ V+AV IA
Sbjct: 13 HALRYASTIRASRRAKLVAISGDGANSALAKVEAKKYGAKFYQNYEQLLKDKSVEAVYIA 72
Query: 71 VPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMVGHVERFNPAVL 130
+ T H+EV + E +L+EKPIA ++E +EI+KAA+K V LMV RF +
Sbjct: 73 IETYRHKEVAIRAAEEGKDILLEKPIALTLEDGKEIVKAARKAGVKLMVPFNPRFTQPLQ 132
Query: 131 KLKETIERGMLGE---IVTMTAKRVGPMV-----------TRISDVGVIIDLAVHDIDVM 176
K KE IE G +G+ I T++ PM R S G +D A H ID +
Sbjct: 133 KAKEMIESGEIGKLEYIYTISEYVKPPMFLEGIDTSWFFDIRKSGGGGFMDTAPHGIDSL 192
Query: 177 SFLTTSRVIEVYAKARNVKHPAKVEDYALILLSFENGANGIIETNRLTPH-----KTRTL 231
+LT S ++VYA + +V+D L+ F+N ++ P
Sbjct: 193 FWLTESEPVKVYADIGSKIWGFEVDDIGTALIEFKNNVIALLTAGWANPKGYPYGLEMKY 252
Query: 232 NVVGTEGIAYLDYINQELTLYNE--EWIYKAKINKEEPLKLEIEHFLECVKEGKKPLVGG 289
+VG +G + + T+Y E E I+ + + E I F++ +++ ++P + G
Sbjct: 253 YIVGDDGFLDIRTAYPDFTVYQEKTEKIFWERADVEG----IINAFIDAIQQDREPPITG 308
Query: 290 EEGLHALKVAVKALESSKKDEVVRVS 315
E+ L L + + A ESSK +VV+++
Sbjct: 309 EDALKNLALVLAAYESSKTGKVVKIN 334
>pir||A81396 hypothetical protein Cj0504c [imported] - Campylobacter jejuni
(strain NCTC 11168) >gi|6967973|emb|CAB75141.1|
(AL139075) hypothetical protein Cj0504c [Campylobacter
jejuni]
Length = 288
Score = 115 bits (286), Expect = 5e-25
Identities = 81/279 (29%), Positives = 145/279 (51%), Gaps = 15/279 (5%)
Query: 1 MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELI 60
M++G++G+GKMG +H +EL+K +L + D+ + F + D + +
Sbjct: 1 MKIGIIGLGKMGQNHL---NELSKNSHFKLNALFDLCKNPNLNI---FDDIFYDDLDKFL 54
Query: 61 KEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMVG 120
+ D + IA PT+ H + + VL+EKP+A +++ EI AK+ ++ + VG
Sbjct: 55 NQNNDIIIIATPTNSHLTIAKKVFKQCKCVLIEKPLALNLKEIDEISNLAKEYSIKVGVG 114
Query: 121 HVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTRISDVGVIIDLAVHDIDVMSFLT 180
ERFNPAVL LK+ +E EI+++ +R P RISDVG++ DLAVHD+D++ FL+
Sbjct: 115 FCERFNPAVLALKKELEN---EEIISINIQRFSPYPQRISDVGILQDLAVHDLDLLCFLS 171
Query: 181 TSRVIEVYAKARNVKHPAKVEDYALILLSFENGANGIIETNRLTPHKTRTLNVVGTEGIA 240
+ + + + + E ++IL E I ++ T K R ++++ T+
Sbjct: 172 KQEITKTNLLKKYTQDQTR-ESESIILCGLEKCIASIHQSWNST-QKLRKIHLI-TKNHF 228
Query: 241 YLDYINQELTLYNEEWIYKAKINKEEPLKLEIEHFLECV 279
Y +N L + +I ++ ++ PL E E L+ +
Sbjct: 229 YEANLNDFSLLKDGNFI---ELTQQSPLFSEHEALLKLI 264
>gb|AAK43113.1| Dehydrogenase, putative [Sulfolobus solfataricus]
Length = 363
Score = 108 bits (268), Expect = 7e-23
Identities = 89/349 (25%), Positives = 172/349 (48%), Gaps = 38/349 (10%)
Query: 1 MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELI 60
M++G+VG+G G+ L G +++ ADI+ +R K++++ + + DY+E++
Sbjct: 4 MKLGIVGLG--GWVTGAHIPALTDLG-IKVDYCADIDEKRVKDLSQKTGCKGYLDYKEML 60
Query: 61 K-EGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMV 119
+ E D V +AVP SLH + +D I N+ +V VEKP+A S + A +++A++K N +L+V
Sbjct: 61 RNENPDLVLVAVPHSLHAIIALDAINNDANVYVEKPMATSFQEALTLVEASRKRNKILVV 120
Query: 120 GHVERFNPAVLKLKETIERGMLGEIVTMTAKRV-------GPMVTR--ISDVGVIIDLAV 170
GH RFNPA+L K+ I G +G+I M + P + ++ G + D+
Sbjct: 121 GHENRFNPAMLIAKKLIRGGEVGKIYHMRGFYIRQRGIPTSPTFIKKDLAKGGAVFDIGT 180
Query: 171 HDIDVMSFLT--------TSRVIEVYA--KARNVKHPA--------KVEDYALILLSFEN 212
H ID++ FL+ T + ++ K + +P+ +VED+ L +
Sbjct: 181 HIIDLLLFLSDFPTPKSVTGKTYNAFSEDKTKFSAYPSPNLPNFKVEVEDFGSAFLKLGD 240
Query: 213 GANGIIETNRLTPHKTRTLNVV--GTEGIAYLD--YINQELTLYNEEWIYKAKINKEEPL 268
+ +E + + K + VV G G ++D +N + +E +I ++ +
Sbjct: 241 EISAYVEVSWASYIKENKMEVVILGDNGGIHIDNGVLNFMRNIEDELFISSPLTQQKGSV 300
Query: 269 KLEI-EHFLECVKEG--KKPLVGGEEGLHALKVAVKALESSKKDEVVRV 314
E+ +E + +G + PL E+G + + +S+ + V++
Sbjct: 301 YREVWRTVMESISKGFPEYPLCSAEQGAIGVAILESIYKSALEGREVKI 349
>dbj|BAB05884.1| (AP001514) unknown conserved protein [Bacillus halodurans]
Length = 348
Score = 107 bits (265), Expect = 2e-22
Identities = 93/346 (26%), Positives = 166/346 (47%), Gaps = 37/346 (10%)
Query: 1 MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTR-AFKDYREL 59
+RVG++G G + I S L+ + +VEL+ + D+ + A+ AE F + D +
Sbjct: 6 LRVGIIGAGGIA-RTVHIPSYLSLKDQVELVAITDVQPKHAQAAAEQFSIPYVYNDASRM 64
Query: 60 IKE-GVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLM 118
++E +DAVSI P + HRE+T++ + VL EKP A ++E A+++ AAK+ +L
Sbjct: 65 MQEVELDAVSICTPNAFHRELTIEALHAGCHVLCEKPPAITVEDAKQMEAAAKETGNLLT 124
Query: 119 VGHVERFNPAVLKLKETIERGMLGEIVTMTAKRV--------GPMVTR-ISDVGVIIDLA 169
G R +P V LK ++ G LGEI + + + G + + G +ID+
Sbjct: 125 YGFHYRHSPEVETLKRFVDEGELGEIYHVRVQAIRRRGIPGWGVFTNKELQGGGPLIDIG 184
Query: 170 VHDID----VMSFLTTSRVIEVYAKARNVKHPA-----------KVEDYALILLSFENGA 214
VH +D VM F + ++ + K +ED A+ +++F+NGA
Sbjct: 185 VHMLDTALYVMGFPEPATILGQTHRKIGTKEGVGLLGEWNWQQFSIEDMAVGMITFKNGA 244
Query: 215 NGIIETNRLTPHKTR---TLNVVGTEGIAYL----DYINQELTLYNEEWIYKAKINKEEP 267
+ IET K + ++ G +G A L Y + TL + +Y N E
Sbjct: 245 SLTIETAFAANVKEQDHMNVSFFGDKGGADLFPLSIYQEKHRTLLDITPVYLPTYNHHE- 303
Query: 268 LKLEIEHFLECVKEGKKPLVGGEEGLHALKVAVKALESSKKDEVVR 313
EI+HF++C ++PL E+G+ ++ +S++ + ++
Sbjct: 304 --REIKHFVDCCFRLEQPLATPEQGIVIQRLIQGLYQSAESGKAIQ 347
>pir||A83617 probable oxidoreductase PA0237 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9946075|gb|AAG03626.1|AE004461_9
(AE004461) probable oxidoreductase [Pseudomonas
aeruginosa]
Length = 347
Score = 102 bits (253), Expect = 4e-21
Identities = 86/340 (25%), Positives = 149/340 (43%), Gaps = 40/340 (11%)
Query: 1 MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELI 60
+R+ ++G G MG H Y L + L VAD + + A F D+R L+
Sbjct: 5 LRIALIGAGNMGRQH---YHRLQRIAGARLCAVAD---PQGQAFAADTGVPWFGDHRRLL 58
Query: 61 KEG-VDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMV 119
+E A +A P +LH +D + V +L+EKP+ ++ E++ A++ V L+V
Sbjct: 59 EEARPQAAIVANPNNLHVATALDCLAAGVPLLLEKPVGVQLDEVSELVAVARRSGVPLLV 118
Query: 120 GHVERFNPAVLKLKETIERGMLGEIVTMTA----KRVGPMV----TRISDVGVIIDLAVH 171
GH R NP V++ ++ I G LG ++++TA K+ R G+++ +H
Sbjct: 119 GHHRRHNPLVVRARQLIAEGALGRLLSVTALWQLKKPDSYFEVAWRREPGAGMLLTNLIH 178
Query: 172 DIDVMSFLTTSRVIEVYAKARNVKHPAKVEDYALILLSFENGANGIIE------------ 219
D+D++ L V EV A A N ED +LL F NGA G +
Sbjct: 179 DLDLLRHL-CGEVREVQALAGNAIRGLPNEDNIALLLRFANGALGSLTGCDAAAAPWSWE 237
Query: 220 ----TNRLTPHKTR--TLNVVGTEGIAYLDYINQ-ELTLYNEEWIYKAKINKE-----EP 267
N + P + + GTEG L + + + W ++E +P
Sbjct: 238 LAAGENPVYPRQAEQPCYLLAGTEGALSLPQLRRWRYAEARQGWHDPLAASEEAVATGDP 297
Query: 268 LKLEIEHFLECVKEGKKPLVGGEEGLHALKVAVKALESSK 307
L+ ++EHF+ + + PL+ + L + E+++
Sbjct: 298 LQRQLEHFVRVARGEEAPLMDATDAARTLALVEAVREAAR 337
>dbj|BAB05939.1| (AP001514) dehydrogenase [Bacillus halodurans]
Length = 345
Score = 102 bits (252), Expect = 5e-21
Identities = 84/340 (24%), Positives = 153/340 (44%), Gaps = 30/340 (8%)
Query: 1 MRVGVVGVGKMGYHHARIYSELA-KEGKVELIGVADINFERAKEVAETFKTR-AFKDYRE 58
++VG+VG+G++G H LA + + EL V + K+ E + + Y E
Sbjct: 4 VKVGLVGLGRLGQQHG---DNLAFRIPRCELTAVCSVVEAEVKQARERWGVPYGYTSYEE 60
Query: 59 LI-KEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKK-MNVV 116
++ E +DA+ IA P+ H E +E V EKP+ + +E+ A + + V
Sbjct: 61 MLANEELDAIFIASPSGFHCEQIKKGLEKGFHVFCEKPLGLHLAEVREVENAVNRHKDQV 120
Query: 117 LMVGHVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPM--------VTRISDVG-VIID 167
M+G + R++P+ KE I RG +GE V + + P + +D G + +D
Sbjct: 121 FMLGFMRRYDPSYQAAKEKINRGEIGEPVLIRCYGLDPASQIDGFLAFAKANDSGGLFLD 180
Query: 168 LAVHDIDVMSFLTTSRVIEVYAKARNVKHPAKVE----DYALILLSFENGANGIIETNRL 223
+++HD D+ + + EV+A + P E + ++ F+N A G+ R
Sbjct: 181 MSIHDFDLARWYLGAEASEVWAIGGSYSRPEFAELGDAETGAAMVRFDNQAIGLFVAGRN 240
Query: 224 TPH----KTRTLNVVGTEGIAYLDYINQELTLYNEEWIYKAKINK-----EEPLKLEIEH 274
H +T + GT I + NQ + + NE + + E+ + E E
Sbjct: 241 CAHGYHIETEIIGTKGTIRIGSIPERNQAVVM-NEHGVIHECVQGFIERFEQAYRAEAEE 299
Query: 275 FLECVKEGKKPLVGGEEGLHALKVAVKALESSKKDEVVRV 314
F+ C+ EG+KP V ++G+ + K+ +S ++ V
Sbjct: 300 FIRCILEGRKPDVTVKDGVESTKLGYACKQSFTTKTLINV 339
>gb|AAK43149.1| Dehydrogenase, putative [Sulfolobus solfataricus]
Length = 371
Score = 97.5 bits (239), Expect = 2e-19
Identities = 95/345 (27%), Positives = 163/345 (46%), Gaps = 36/345 (10%)
Query: 3 VGVVGVGKMGYHHARIYSELAKEGK-VELIGVADINFERAKEVAETFKTRAFKDYRELIK 61
V VVG+G +G H + +L KE + V+L+ V D A+++ + T + E+++
Sbjct: 22 VAVVGLGSIGKTHVKALKDLEKETEFVKLVAVVDQIKAIAEKIGSEYGTPYYTTIDEVLR 81
Query: 62 EG-VDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMVG 120
VD +SIA P+ LH + IE V+VEKP+A ++ A+E++ A++ V L V
Sbjct: 82 NSEVDVISIATPSYLHAPQAILAIEYGKHVIVEKPMATTLAGAREMVSRAERNEVKLGVI 141
Query: 121 HVERFNPAVLKLKETI----------------ERGMLGEIVTMTAKRVGPMVTRISDVGV 164
ER+ P + +LK I R M G R + GV
Sbjct: 142 FQERYAPDIRRLKNDILKELGRIYLIESELKWYRDMKGYYKRDEIARSWRGMWNTEGGGV 201
Query: 165 IIDLAVHDIDVMSFLTTSRVIEVYAKARNVKHPA-KVEDYALILLSFENGANGIIE---T 220
+ + +H ID+M +L V EV N+ H +VED A+ ++ ++NGA G I +
Sbjct: 202 MTNQGIHTIDLMIWL-NGEVEEVSGFVDNLTHDGIEVEDTAVAIMRYKNGALGTISQTVS 260
Query: 221 NRLTPHKTRTLNVVGTEGIAYLDYINQEL-TLYNEEWIYKAKINKE-------EPLKLE- 271
+ T ++ R + V G+ G +++ + L T+ E I ++K + E +P L
Sbjct: 261 MKPTTYQYRKIRVNGSNG--FVEITDGSLSTVAIEGKIEESKSSVEYKKETIAQPGNLHK 318
Query: 272 --IEHFLECVKEGKKPLVGGEEGLHALKVAVKALESSKKDEVVRV 314
+ FL + E + G+EG+ +L+V SS +VV++
Sbjct: 319 ELLRDFLRALSEDNDFPINGKEGMKSLEVIKAVYLSSVNRQVVKL 363
>gb|AAC31183.1| (AF076240) putative NADH-inositol dehydrogenase MocA [Rhizobium
leguminosarum bv. viciae]
Length = 306
Score = 96.0 bits (235), Expect = 5e-19
Identities = 82/315 (26%), Positives = 132/315 (41%), Gaps = 29/315 (9%)
Query: 2 RVGVVGVGKMGYHHARIYSE---LAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRE 58
R+G++G G+MG H R SE + VE + + ER+ + +K E
Sbjct: 5 RLGLIGAGRMGQVHLRAASESLLVEVTAVVEPVAATRLALERSG-------IKTYKTADE 57
Query: 59 LIKEG-VDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVL 117
+I G +D V IA P+ H E + + +L EKP + E A++ +AA++ V L
Sbjct: 58 MIDAGEIDGVLIATPSKTHVENITNIAARGLPILCEKPCGVTAEEARKAAEAAEQFKVHL 117
Query: 118 MVGHVERFNPAVLKLKETIERGMLGE---IVTMTAKRVGPMVT-RISDVGVIIDLAVHDI 173
+G+ RF P + KL++ I G+LGE I P + R + G +ID+ VH+
Sbjct: 118 QIGYWRRFVPELEKLRQNIRSGLLGEPYLISCFQWDETPPAASFRATGGGALIDMGVHEF 177
Query: 174 DVMSFLTTSRVIEVYAKARNVKHPAKVE---DYALILLSFENGANGIIET-NRLTPHKTR 229
D M +LT A KVE D +L G G++ R P
Sbjct: 178 DQMRWLTGQEPSNFRVAASKTTFAGKVEGDPDAVQLLCDLSGGGVGLVSLGRRFPPGDAC 237
Query: 230 TLNVVGTEGIAYLDYINQELTLYNEEWIYKAKINKEEPLKLEIEHFLECVKEGKKPLVGG 289
V GT G + + W + L+ ++E F++ + G
Sbjct: 238 WAQVFGTSGFEEVRFF----------WPPNGEAVFLNALRSQLEDFVQAARGGASQGATA 287
Query: 290 EEGLHALKVAVKALE 304
++ + AL +A A E
Sbjct: 288 QDAVTALAIAEAATE 302
>emb|CAB88961.1| (AL353864) putative oxidoreductase. [Streptomyces coelicolor A3(2)]
Length = 358
Score = 94.4 bits (231), Expect = 1e-18
Identities = 66/241 (27%), Positives = 112/241 (46%), Gaps = 14/241 (5%)
Query: 1 MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELI 60
MR+G++G+G++G HA + L G + VAD + AK AE F +
Sbjct: 25 MRIGILGLGRIGAFHAETLAGLDSVGSLV---VADPFADAAKAAAERFGAEVADSPEAVF 81
Query: 61 KEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMVG 120
GVD V IA T H ++ + +E V V EKP+A ++ E++KA +V + +G
Sbjct: 82 AAGVDGVVIAAATDAHPDLILAAVEAGVPVFCEKPVARTMAEGVEVLKALAGRDVPVQIG 141
Query: 121 HVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTRISDV----GVIIDLAVHDIDVM 176
+ RF+ + + G LG + T+ + + P + V G+ D +VHD D +
Sbjct: 142 YQRRFDTGFAAARAAVRSGELGPLHTVRSTTLDPAPPPAAYVAASGGIFRDCSVHDFDSI 201
Query: 177 SFLTTSRVIEVYA----KARNVKHPAKVEDYALILLSFENGANGIIETNRLTPHKTRTLN 232
++T V EVYA + + A D +L+ ++G ++ +R H R +
Sbjct: 202 RWVTGREVGEVYAVGGNRGADYIREAGDADTTGAVLTLDDGTVAVVSNSR---HNARGYD 258
Query: 233 V 233
V
Sbjct: 259 V 259
>sp|P49307|MOCA_RHIME RHIZOPINE CATABOLISM PROTEIN MOCA >gi|2120810|pir||S51572 mocA
protein - Rhizobium meliloti >gi|468762|emb|CAA55269.1|
(X78503) mocA [Sinorhizobium meliloti]
Length = 317
Score = 93.6 bits (229), Expect = 3e-18
Identities = 81/318 (25%), Positives = 135/318 (41%), Gaps = 25/318 (7%)
Query: 2 RVGVVGVGKMGYHHARIYSELAKEGKVELIGVAD-INFERAKEVAETFKTRAFKDYRELI 60
R+G+VG G+MG H R +E VE+ VAD I R KT ++ ++I
Sbjct: 5 RLGLVGAGRMGQVHVRAAAE---SSLVEIAAVADPIAASRLNLAGNGIKT--YETAGDMI 59
Query: 61 KEG-VDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMV 119
+ G VD V IA P++ H + D + +L EKP + E A++ A++ V L +
Sbjct: 60 EAGEVDGVLIATPSNTHVDTVADIAARGLPILCEKPCGVTAEEARKAADVAERYKVHLQI 119
Query: 120 GHVERFNPAVLKLKETIERGMLGEIVTMTAKR--VGPMVT--RISDVGVIIDLAVHDIDV 175
G+ RF P + +L++ I G+LG + ++ + P R + G ID+ VH+ D
Sbjct: 120 GYWRRFVPELKQLRDDIRAGLLGNLYLVSCFQWDEAPPANSFRATGGGAFIDMGVHEFDQ 179
Query: 176 MSFLTTSRVIEVYAKARNVKHPAKVE---DYALILLSFENGANGIIET-NRLTPHKTRTL 231
M +LT V+ D +L +G++G++ R P
Sbjct: 180 MRWLTGQEPTNFRVATSKTTFAGAVKGDPDAVQLLCDLSDGSSGLVSLGRRFPPGDACWT 239
Query: 232 NVVGTEGIAYLDYINQELTLYNEEWIYKAKINKEEPLKLEIEHFLECVKEGKKPLVGGEE 291
V GT G A + W + L+ ++E F++ + G +
Sbjct: 240 QVFGTSGFAEARFF----------WPPDGEAVFLNALQAQLEDFVQAARGGAPRGATASD 289
Query: 292 GLHALKVAVKALESSKKD 309
+ AL +A A E +D
Sbjct: 290 AVAALTIAEAATELLSRD 307
>pir||B75475 glucose-fructose oxidoreductase - Deinococcus radiodurans (strain
R1) >gi|6458511|gb|AAF10376.1|AE001934_7 (AE001934)
glucose-fructose oxidoreductase [Deinococcus
radiodurans]
Length = 398
Score = 93.2 bits (228), Expect = 3e-18
Identities = 81/338 (23%), Positives = 158/338 (45%), Gaps = 30/338 (8%)
Query: 2 RVG--VVGVGKMGYHHARIYSELAKEGKVELIGVADIN----FERAKEVAETFKTRAFKD 55
RVG +VG+GK+ + ++ + + ++ + F RA ++ ++ D
Sbjct: 44 RVGFAIVGIGKLSAEELIPAARTSQHAYIAALVTSEEDKGEAFARAFDLTPD-DVYSYDD 102
Query: 56 YRELI-KEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMN 114
+ +L ++ V+AV I +P SLHRE + VL EKP++ + + AQ ++ A + N
Sbjct: 103 FEKLAGRDDVEAVYIVLPNSLHREYVERAAKMGKHVLCEKPLSVNEQDAQAMVDACRAAN 162
Query: 115 VVLMVGHVERFNPAVLKLKETIERGMLGEIVTMTAKRV----GPMVTR----ISDVGVII 166
V+LM + ++ P ++ ++ G LG++ + + V P V R ++ G +
Sbjct: 163 VLLMTAYRCQYTPEHWAARDAVQGGKLGKVKLLDSIHVQSEDDPSVWRLKLDLAGGGPLP 222
Query: 167 DLAVHDIDVMSFLTTSRVIEVYAKARNVKHP---AKVEDYALILLSFENGANGIIETNRL 223
D+ ++ ++++ F+ V+A + +VE+ +L F G + N L
Sbjct: 223 DVGLYSVNIIRFVLGQEPEWVFAALHQPEGDPRFGEVEESVSAMLGFPGG----VIANVL 278
Query: 224 TPH---KTRTLNVVGTEGIAYLD----YINQELTLYNEEWIYKAKINKEEPLKLEIEHFL 276
T + KT TL V+G EG +D Y L + ++ + + + E +HF
Sbjct: 279 TSYGALKTTTLRVMGEEGSLLMDPAFPYDGLGLEITTDDGTFSPSFPEYDQFSREFDHFA 338
Query: 277 ECVKEGKKPLVGGEEGLHALKVAVKALESSKKDEVVRV 314
+CV+ G+ P GEEG+ +V ES++ + V +
Sbjct: 339 QCVRGGQTPWTPGEEGVADHRVMDAIYESARTGKRVEL 376
>dbj|BAB04429.1| (AP001509) unknown conserved protein [Bacillus halodurans]
Length = 388
Score = 92.1 bits (225), Expect = 8e-18
Identities = 96/383 (25%), Positives = 164/383 (42%), Gaps = 68/383 (17%)
Query: 1 MRVGVVGVGKMGYHHARIYSELAK----EGKVELIGVADINFERAKEVAETFKTRAFK-D 55
++VG++G MG H+ Y +L + E+ + N E + A + + +
Sbjct: 4 IKVGMIGYKFMGKAHSHAYRDLPMFFPDHLRPEMKVICGRNPEGVAQAASQYGWEEYTTN 63
Query: 56 YRELIK-EGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMN 114
+++LI+ + +D + I P+ +H+E+T+ + + EKP+A +++ ++ +++A +
Sbjct: 64 WKDLIRRDDIDLIDINAPSDVHKEITLAAAQAGKHIFCEKPLALTLQDSRHMLEAVEAAG 123
Query: 115 VVLMVGHVERFNPAVLKLKETIERGMLGEIVTMTAKRVG--------PMVTR----ISDV 162
V MVG RF PAVL K+ I G LG+I A + P+V R I+
Sbjct: 124 VKHMVGFNYRFTPAVLLAKKLIAEGRLGDIYHFRAWFLQDWIVAPDFPLVWRLQKDIAGS 183
Query: 163 GVIIDLAVHDIDVMSFL--TTSRVI---EVYAKARNV------------------KHPAK 199
G DL H ID+ FL + VI E + K R + K P
Sbjct: 184 GAHGDLGAHLIDMAHFLIGDITEVIGMNETFIKERPLPTEMTGLSGRGSNDHTVPKGPVT 243
Query: 200 VEDYALILLSFENGANGIIETNRL-TPHK-TRTLNVVGTEGIAYLDYIN-QELTLY---- 252
V+D L + F NGA G E R T H+ T + + G++G D+ EL +Y
Sbjct: 244 VDDATLFMARFANGALGSFEATRFATGHRSTNSFEINGSKGSVIFDFERLNELQVYFTDD 303
Query: 253 --------------------NEEWIYKAKINKEEPLKLEIEHFLECVKEGKKPLVGGEEG 292
+ W I E EI +E ++EG++P+ ++G
Sbjct: 304 QDDVQGFRRVLATDGAHAYSDRWWPAGHTIGYEHTFIHEIAELMESLQEGRQPVPNFKDG 363
Query: 293 LHALKVAVKALESSKKDEVVRVS 315
+ +V S K E ++VS
Sbjct: 364 VKCQQVLEAVDLSIAKREWIQVS 386
>gb|AAC23913.1| (AF039207) NADH-dependent dehydrogenase homolog [Listeria
monocytogenes]
Length = 358
Score = 91.7 bits (224), Expect = 1e-17
Identities = 90/360 (25%), Positives = 157/360 (43%), Gaps = 55/360 (15%)
Query: 1 MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETF---KTRAFKDYR 57
++VG++G G G + + L K K E++ DI E+A+ A+ F + +Y
Sbjct: 3 LKVGIIGCG--GIANGKHMPSLLKAEKAEMVAFCDIVLEKAEAAAKEFGGENASVYTNYV 60
Query: 58 ELIKE-GVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVV 116
EL+++ +D + + P H E+++ +E V+ EKP+A++ A+ +I+AA++
Sbjct: 61 ELLQDKSIDVIHVCTPNISHAEISIAAMEAGKHVMCEKPMAKTTAEAKSMIEAAERTGKK 120
Query: 117 LMVGHVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTRISDV---------GVIID 167
L +G+ RF L + E G LG+I AK + V G +ID
Sbjct: 121 LTIGYQNRFRKDSDYLHQVCENGELGDIYYAKAKAIRRRAVPTWGVFLDEEAQGGGPLID 180
Query: 168 LAVHDIDVMSFL--------TTSRVIEVYAKARNVKH------PAK--VEDYALILLSFE 211
+ H +D+ ++ AK N + P K VED A ++ E
Sbjct: 181 IGTHALDLTLWMMDNYKPKYVVGNSYHKLAKKENAANAWGSWDPNKFTVEDSAFGFITME 240
Query: 212 NGANGIIET----NRLTPHKTRTLNVVGTEGIAYLD---YINQELTLYNEEWIYKAKINK 264
NGA ++E N L + RT ++ GTEG A ++ IN E +Y+ KI
Sbjct: 241 NGATIVLEASWALNTLDVGEART-SLSGTEGGADMEDGLRINGEA----HSQMYEKKIQL 295
Query: 265 E------------EPLKLEIEHFLECVKEGKKPLVGGEEGLHALKVAVKALESSKKDEVV 312
E +P +E +L +++ P+V + + ++ ESSK + V
Sbjct: 296 EAGGVDFYDGTGDDPALIEAGQWLGAIEKNTDPVVKPGQAIVVTQILEAIYESSKTGQPV 355
>emb|CAB60174.1| (AL132824) putative dehydrogenase [Streptomyces coelicolor]
Length = 337
Score = 90.9 bits (222), Expect = 2e-17
Identities = 66/231 (28%), Positives = 103/231 (44%), Gaps = 11/231 (4%)
Query: 1 MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELI 60
MR+GV+G G++G HA S G + L D + RA+E+A A E+
Sbjct: 1 MRIGVIGTGRIGTVHANTLSRHRDVGSLIL---TDADIARAQELAHRLGETAAPGVDEIF 57
Query: 61 KEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMVG 120
+ GVDAV I T H E+ + + V EKPIA + + I + VL +G
Sbjct: 58 QWGVDAVVITTATPAHAELIGRAARSGLPVFCEKPIALDLPGTLQAIAEVEAAGTVLQMG 117
Query: 121 HVERFNPAVLKLKETIERGMLGEIVT---MTAKRVGPMVTRISDVGVII-DLAVHDIDVM 176
RF+ +E + G LG + T +T+ + P + G + D +HD DV+
Sbjct: 118 FQRRFDTGYTGAREAVRSGRLGRLHTVRAVTSDQTPPPADYLPQSGGLYRDTLIHDFDVL 177
Query: 177 SFLTTSRVIEVYAKARNVKHP----AKVEDYALILLSFENGANGIIETNRL 223
++T V++VYA + P A D +LL+ ++G RL
Sbjct: 178 RWVTGREVVDVYAAGSDAGPPMFRAADDVDTGAVLLTLDDGTLATATAARL 228
>sp|O68965|MI2D_RHIME MYO-INOSITOL 2-DEHYDROGENASE >gi|3088561|gb|AAC70005.1| (AF059313)
myo-inositol dehydrogenase [Sinorhizobium meliloti]
Length = 330
Score = 88.5 bits (216), Expect = 9e-17
Identities = 79/331 (23%), Positives = 142/331 (42%), Gaps = 19/331 (5%)
Query: 1 MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELI 60
+R G++G G++G HA+ S A L+ VAD A+ +A +
Sbjct: 3 VRFGLLGAGRIGKVHAKAVSGNAD---ARLVAVADAFPAAAEAIAGAYGCEVRTIDAIEA 59
Query: 61 KEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMVG 120
+DAV I PT H ++ F ++ EKPI E + +K LMVG
Sbjct: 60 AADIDAVVICTPTDTHADLIERFARAGKAIFCEKPIDLDAERVRACLKVVSDTKAKLMVG 119
Query: 121 HVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTRISDV----GVIIDLAVHDIDVM 176
RF+P + +++ I+ G +GE+ +T P + + G+ D+ +HD D+
Sbjct: 120 FNRRFDPHFMAVRKAIDDGRIGEVEMVTITSRDPSAPPVDYIKRSGGIFRDMTIHDFDMA 179
Query: 177 SFLTTSRVIEVYAKARNVKHPAKVE----DYALILLSFENGANGII-ETNRLTPHKTRTL 231
FL + V A A + A + D ++L +G II + R T + +
Sbjct: 180 RFLLGEEPVSVTATAAVLIDKAIGDAGDYDSVSVILQTASGKQAIIANSRRATYGYDQRI 239
Query: 232 NVVGTEGIAYLDY---INQELTL---YNEEWIYKAKINK-EEPLKLEIEHFLECVKEGKK 284
V G++G + ++ E+ Y ++ + + E EIE F+ +++G +
Sbjct: 240 EVHGSKGAVAAENQRPVSIEIATGDGYTRPPLHDFFMTRYTEAYANEIESFIAAIEKGAE 299
Query: 285 PLVGGEEGLHALKVAVKALESSKKDEVVRVS 315
G +GL AL +A A+ S + + ++
Sbjct: 300 IAPSGNDGLAALALADAAVRSVAEKRQISIA 330
>sp|Q05184|PHT4_PSEPU PUTATIVE 4,5,-DIHYDROXYPHTHALATE DEHYDROGENASE (DHP DEHYDROGENASE)
>gi|295711|dbj|BAA02512.1| (D13229) PHT4 [Pseudomonas
putida]
Length = 410
Score = 85.0 bits (207), Expect = 1e-15
Identities = 65/231 (28%), Positives = 97/231 (41%), Gaps = 13/231 (5%)
Query: 1 MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELI 60
+R+GVVG+G+ + + +V+L+G D + ++ F A++ +L
Sbjct: 12 LRLGVVGLGRA---FTLMLPTFLADRRVQLVGACDPREQARRQFERDFDAPAYETIEDLA 68
Query: 61 KEG-VDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMV 119
+ VDA+ IA P H E T N VLVEKP+A S++ +I + V L+V
Sbjct: 69 ADSNVDALYIASPHQFHAEHTRIAAANRKHVLVEKPMALSLDECDRMIADCAEAGVKLIV 128
Query: 120 GHVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTR---------ISDVGVIIDLAV 170
GH F+ L+ +E I G G + + A + R G + A
Sbjct: 129 GHCHSFDTPYLRTRELIGSGEFGAVKMIQALNYTDYLQRPRRPEELSTAEGGGAVFSQAA 188
Query: 171 HDIDVMSFLTTSRVIEVYAKARNVKHPAKVEDYALILLSFENGANGIIETN 221
H +DV+ L SR V A N E L FENGA I N
Sbjct: 189 HQVDVVRLLAGSRATRVRAAVGNWDPARPTEGAYTATLWFENGAFASITYN 239
>sp|Q54728|YJHC_STRPN HYPOTHETICAL PROTEIN IN NANB 3'REGION (ORF-5)
>gi|1163116|gb|AAC44397.1| (U43526) ORF-5 [Streptococcus
pneumoniae]
Length = 347
Score = 85.0 bits (207), Expect = 1e-15
Identities = 69/264 (26%), Positives = 117/264 (44%), Gaps = 18/264 (6%)
Query: 1 MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELI 60
++ GVVG G G AR Y + ++ L+ D A+ +AE + EL+
Sbjct: 2 VKYGVVGAGYFGAELAR-YMQKNDGAEITLLYDPD----NAEAIAEELGAKVASSLDELV 56
Query: 61 K-EGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMV 119
+ VD V +A P +LH+E + ++ +V EKPIA S + +E++ A K+ NV M
Sbjct: 57 SSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCREMVDACKENNVTFMA 116
Query: 120 GHVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTRIS--------DVGVIIDLAVH 171
GH+ F V KE I +G++G+++ R G ++S G + +H
Sbjct: 117 GHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQLSVSWKKIREKSGGHLYHHIH 176
Query: 172 DIDVMSFLTTSRVIEVYAKARNVKHPAK----VEDYALILLSFENGANGIIETNRLTPHK 227
++D + FL V NV H + +D + + F N ++E
Sbjct: 177 ELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNMEFSNKRFALLEWGSAYRWG 236
Query: 228 TRTLNVVGTEGIAYLDYINQELTL 251
+ + G++G LD N + TL
Sbjct: 237 EHYVLIQGSKGAIRLDLFNCKGTL 260
>emb|CAC11912.1| (AL445065) hypothetical protein [Thermoplasma acidophilum]
Length = 322
Score = 82.7 bits (201), Expect = 5e-15
Identities = 74/258 (28%), Positives = 114/258 (43%), Gaps = 30/258 (11%)
Query: 1 MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKT-----RAFKD 55
M V ++G HA Y L E V ++R +V E ++ + D
Sbjct: 6 MSVLLIGGNGFAKVHAETYRRLGIEFSV---------YDRNPQVLEMYRRDYGVRETYSD 56
Query: 56 YRELIKEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNV 115
+ DAV I +P +LH EV M IE VLVEKP+ I+ A +II AKK +
Sbjct: 57 MAAALDADNDAVDIVLPHNLHYEVAMKAIEKGKHVLVEKPVTGRIDEAVKIINQAKKKRL 116
Query: 116 VLMVGHVERFNPAVLKLKETIERGMLGEIVTMTAK-----RVGPMVTRISDV--GVIIDL 168
MV F+P+ K E ++ G +G++ T+ + +R +++ G +ID
Sbjct: 117 KFMVAEQFYFDPSFRKALEIVQSGKIGDVRTVIVRDQQRYDAPGWRSRKNEMMGGSLIDG 176
Query: 169 AVHDIDV-MSFLTTSRVIEVYAKARNVKHPAKV--EDYALILLSFENGANGII--ETNRL 223
VH +++ + F + I A N K + ED L +FEN +GI + +
Sbjct: 177 GVHFLEIFLDFGGQWKSI----SAHNYKGGTSIEGEDNTAALFTFENDVHGIFYYSWSYV 232
Query: 224 TPHKTRTLNVVGTEGIAY 241
P K V+GTEG Y
Sbjct: 233 EPPKLPAFEVIGTEGSVY 250
>gb|AAG09709.1|AF218837_4 (AF218837) unknown [Pasteurella multocida]
Length = 367
Score = 82.3 bits (200), Expect = 6e-15
Identities = 68/264 (25%), Positives = 121/264 (45%), Gaps = 18/264 (6%)
Query: 1 MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELI 60
M+ GVVGVG G AR +E + KV ++ + E + +A+ + A ++L+
Sbjct: 2 MKYGVVGVGYFGADLARFMNE-NENAKVTMV----YDPENGETIAKELQCIAATSLKQLV 56
Query: 61 KEG-VDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMV 119
VD V +A P LH+E ++ ++ V EKPIA + + E+++ ++ V+ M
Sbjct: 57 SSPEVDCVIVATPNYLHKEPVIEAAKHGKHVFCEKPIALNYQDCDEMVRTCEENGVIFMA 116
Query: 120 GHVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTRIS--------DVGVIIDLAVH 171
GHV F V KE I++G++G+++ + R G + S G + +H
Sbjct: 117 GHVMNFFNGVHHAKELIKQGVIGKVLYCHSARNGWEDEQSSISWKKIRAKSGGHLYHHIH 176
Query: 172 DIDVMSFLTTSRVIEVYAKARNVKHPAK----VEDYALILLSFENGANGIIETNRLTPHK 227
++D + F+ V A NV H ++ +D + L FE G ++E
Sbjct: 177 ELDCIQFIMGGMPKTVTMTAGNVAHQSEKFGDEDDMLFLNLEFEGGRFAVLEWGSAFRWG 236
Query: 228 TRTLNVVGTEGIAYLDYINQELTL 251
+ + G +G LD + + TL
Sbjct: 237 EHYVLIQGEKGAIKLDMYHCKGTL 260
>sp|P09400|STRI_STRGR STREPTOMYCIN BIOSYNTHESIS PROTEIN STRI >gi|80803|pir||S17779 strI
protein - Streptomyces griseus >gi|49268|emb|CAA68521.1|
(Y00459) NAD:myo-inositol oxidoreductase [Streptomyces
griseus]
Length = 348
Score = 82.3 bits (200), Expect = 6e-15
Identities = 88/323 (27%), Positives = 137/323 (42%), Gaps = 25/323 (7%)
Query: 1 MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFER-AKEVAETFKTRAFKDYREL 59
MRVG+VG G+MG HAR EL + + V R A+E+A K + + REL
Sbjct: 1 MRVGIVGAGRMGRLHARTLLELPDPPDLVVHDVDPDGAHRLAQELAAGTKAQVTVE-REL 59
Query: 60 IK--EGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVL 117
DA+ +A P + R + + V EKP+ A E+++A + L
Sbjct: 60 ADTVTKADAIVVATPATQRRAPLLAAARAGLPVFCEKPLTADETEAAELVEAL--AHTRL 117
Query: 118 MVGHVERFNPAVLKLKETIERGMLGEI--VTMTAKRVGPMVTRISDVG--VIIDLAVHDI 173
VG R +P +L+E I G LG + V TA P + + D +HDI
Sbjct: 118 HVGFQRRCDPEYQRLRELIAAGELGRVLLVRCTAFDHRPPADAYEETAGDIFTDCLIHDI 177
Query: 174 DVMSFLTTSRVIEVYAKARNVKHPAKVEDYALILLSFENGANGIIETNRLTPH-KTRTLN 232
D + +LT + V A + D A +L+ +GA ++ +RL PH +
Sbjct: 178 DAVHWLTGQPTVAVQADGARLL-AGSGYDVATAVLTLADGARAVLSASRLDPHGYDHRVE 236
Query: 233 VVGTEGIAYLDY-INQELTLYNEEW-----------IYKAKINK-EEPLKLEIEHFLECV 279
V+GT+G + L L ++ Y+ ++ E + E+ F+ V
Sbjct: 237 VLGTKGSLSVGLDARTPLRLLGQDGTGCPPGPGAQPAYQDFTDRFEAAYRREVLAFVRTV 296
Query: 280 KEGKKPLVGGEEGLHALKVAVKA 302
EG G+E L A +VA A
Sbjct: 297 TEGAPSPCTGQEALRAQRVAAAA 319
>pir||S70672 dehydrogenase homolog - Bordetella pertussis
>gi|992971|emb|CAA62245.1| (X90711) gene referred to as
bplA in Mol. Microbiol. 19:37-52(1996) [Bordetella
pertussis] >gi|3451515|emb|CAA07671.1| (AJ007747)
putative oxidoreductase [Bordetella bronchiseptica]
>gi|1589221|prf||2210367C bplA gene [Bordetella
pertussis]
Length = 350
Score = 82.3 bits (200), Expect = 6e-15
Identities = 80/344 (23%), Positives = 148/344 (42%), Gaps = 44/344 (12%)
Query: 1 MRVGVVGVGKMGYHHARIYSELAKEG-KVELIGVADINFERAKEVAETFKTRAFKDYREL 59
+R G+VG G++ +H +A+ G + EL+ + D N E + R F ++
Sbjct: 11 IRFGLVGCGRISKNHI---GAIAQHGDRAELVEICDTNPEALQAAEAATGARPFSSLSDM 67
Query: 60 IKEG-VDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLM 118
+ +G DA+ +A P+ LH ++ + V+ EKP+A E + ++KA + V L
Sbjct: 68 LAQGNADALVLATPSGLHPWQAIEVAQAGRHVVSEKPMATRWEDGKRMVKACDEAGVRLF 127
Query: 119 VGHVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTRIS--------------DVGV 164
V R N + +K+ IE+G G I +T V TR D G
Sbjct: 128 VVKQNRRNATLQLVKKAIEQGRFGRIYMVT---VNVFWTRPQEYYDAARWRGKWEWDGGA 184
Query: 165 IIDLAVHDIDVMSFLTTSRVIEVYAKARNVKHPAKVEDYALILLSFENGANGIIETNRLT 224
++ A H +D++ +L V VYA + + ED + L + +GA G I LT
Sbjct: 185 FMNQASHYVDLLDWL-VGPVESVYAYTATLARRIEAEDTGVAALRWRHGAMGSINVTMLT 243
Query: 225 --PHKTRTLNVVGTEGIAYLDYINQELTLYNEEWIYKAKINKEEPLK------------- 269
+ ++ ++G +G + + +EW + ++ ++
Sbjct: 244 YPQNLEGSITILGEKGTVRVGGVAVNRI---DEWKFAEPHPDDDKIREANYETTSVYGFG 300
Query: 270 --LEIEHFLECVKEGKKPLVGGEEGLHALKVAVKALESSKKDEV 311
L ++ + C++ +P G EGL +L + + A+ S +D V
Sbjct: 301 HPLYYDNVINCLRGDCEPETDGREGLQSLAL-LTAIYRSARDGV 343
>dbj|BAB05940.1| (AP001514) unknown conserved protein [Bacillus halodurans]
Length = 345
Score = 81.9 bits (199), Expect = 8e-15
Identities = 78/335 (23%), Positives = 138/335 (40%), Gaps = 27/335 (8%)
Query: 1 MRVGVVGVGKMGYHHARI-----YSELAKEGKVELIGVADINFERAKEVAETFKTRAFKD 55
+ +G++G G++G HA Y EL V+L + ER+ E+ T F +
Sbjct: 4 VNIGLIGAGRIGQLHASNIISSPYMELKAVSDVQLDHLKGTEIERSVEIMTTNPDELFSN 63
Query: 56 YRELIKEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNV 115
+DA+ I T H + EKPI+ + + + + V
Sbjct: 64 ------RDIDAIFICSSTDTHAAFIKAAALAGKHIFCEKPISFHVTETKGALNIVNEAGV 117
Query: 116 VLMVGHVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTRISDV----GVIIDLAVH 171
VG R++ +++E ++ G +G + P +S V G+ +D+ +H
Sbjct: 118 KFQVGFNRRYDKHFRRVQECVQAGAIGAPHIIRVSSRDPEAPPLSYVERSGGMFMDMTIH 177
Query: 172 DIDVMSFLTTSRVIEVYAKARNVKHPAKVE----DYALILLSFENGANGIIETNRLTPH- 226
D D++ +L+ S V EV KA N+ E D A+I L ENGA +I+ +R +
Sbjct: 178 DFDMVRYLSGSEVTEVSVKAANLVDSRIGEVGDVDTAIITLMLENGAIAVIDNSRQAAYG 237
Query: 227 KTRTLNVVGTEGIAYLDYINQELTLYNEEWIYKAKINK-------EEPLKLEIEHFLECV 279
+ + V G+ G D + + + + K E+ K E+ F +
Sbjct: 238 YDQRVEVFGSLGSVSADNERKTNVQISTKDTVTLDLPKHFFLDRYEQAYKDEVAEFATAI 297
Query: 280 KEGKKPLVGGEEGLHALKVAVKALESSKKDEVVRV 314
E + GE+G A +A+ A +S ++ V V
Sbjct: 298 LEDQPLRCTGEDGYKAELLALAAKQSWLENRPVAV 332
>dbj|BAB06035.1| (AP001515) myo-inositol 2-dehydrogenase [Bacillus halodurans]
Length = 348
Score = 81.9 bits (199), Expect = 8e-15
Identities = 81/302 (26%), Positives = 136/302 (44%), Gaps = 24/302 (7%)
Query: 1 MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRA--FKDYRE 58
+R GV+G G +G H + GK+ + V D+N E AK+V K A + D R
Sbjct: 3 LRFGVIGTGAIGREHMKRIENKLSGGKI--VAVTDMNQEAAKQVVTQMKLEADVYPDDRS 60
Query: 59 LIK-EGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMN--- 114
L+ + VDAV + H + IE V VEKP+A + E +IIKA +MN
Sbjct: 61 LVAADNVDAVLVTSWGPAHEANVLAAIEAGKYVFVEKPLATTAEGCMKIIKA--EMNHGK 118
Query: 115 VVLMVGHVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMV--TRISDVGVIIDLAVHD 172
++ VG + R++ ++LK+ I+ +GE + + P V + I D+ I D +H+
Sbjct: 119 RLVQVGFMRRYDKGYVQLKKAIDDHFIGEPLMVRCAHRNPEVGESYIDDM-AIHDTLIHE 177
Query: 173 IDVMSFLTTSRVIEVYAK-ARNVKHP-AKVEDYALILLSFENGANGIIETNRLTPHK--- 227
IDV+ +L V + KH + D ++ L + G +I K
Sbjct: 178 IDVLHWLIDDEYESVSVSFPKKTKHALPHLRDPRVVTLETKGGV--LITAEVFVNCKYGY 235
Query: 228 TRTLNVVGTEGIAYLDYIN----QELTLYNEEWIYKAKINKEEPLKLEIEHFLECVKEGK 283
V+ EGIA L ++ ++ + K E +E++HF++ +K+
Sbjct: 236 DIQCEVIREEGIASLPEVDSISFRKRATLGTNILMDWKQRFIEAYDVELQHFIDSIKQSG 295
Query: 284 KP 285
+P
Sbjct: 296 EP 297
>gb|AAD51832.1|AF175299_7 (AF175299) ThuB [Sinorhizobium meliloti]
Length = 365
Score = 81.1 bits (197), Expect = 1e-14
Identities = 71/252 (28%), Positives = 113/252 (44%), Gaps = 33/252 (13%)
Query: 1 MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTR-AFKDYREL 59
MR+ ++G G M HA+ ++E+ EG VE++G D++ RAK A T F +
Sbjct: 6 MRLLILGTGGMANSHAKAFAEI--EG-VEMVGAVDVDPSRAKAFAVTHGIENTFTSLDDA 62
Query: 60 IKEG-VDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLM 118
I G DA + P H T+ I VL EKP+AE+ E A E+ AA++ +V M
Sbjct: 63 IAWGEFDAATNVTPDKAHHPTTLALIAAGKHVLCEKPLAENYEKAAEMAAAAERAGLVTM 122
Query: 119 VGHVERFNPAVLKLKETIERGMLGEIVTMTA-------------------KRVGPMVTRI 159
V R + K +E + G +G + + A K + + T+
Sbjct: 123 VNLTYRNVAPLQKARELVVAGEIGRVRHLEASYLQSWLVSRAWGDWASESKWLWRLSTKH 182
Query: 160 SDVGVIIDLAVHDIDVMSFLTTSRVIEVYA--KARNVKHPAKVEDYAL-------ILLSF 210
GV+ D+ +H +D + S V V+A KA + ++ +Y L + F
Sbjct: 183 GSNGVLGDVGIHILDFAGYGANSSVERVFARLKAFDKAPDNRIGEYDLDANDSFAMTAEF 242
Query: 211 ENGANGIIETNR 222
ENGA +I +R
Sbjct: 243 ENGAMAVIHASR 254
>emb|CAB88965.1| (AL353864) putative oxidoreductase. [Streptomyces coelicolor A3(2)]
Length = 387
Score = 79.2 bits (192), Expect = 6e-14
Identities = 81/283 (28%), Positives = 116/283 (40%), Gaps = 41/283 (14%)
Query: 3 VGVVGVGKMGYHHARIYSELAKEG-----KVELIGVADINFERAKEVAETFK-TRAFKDY 56
V VVG G MG H + Y+ + + EL+ VA+ RA+E A F +D+
Sbjct: 7 VAVVGFGWMGRVHTQAYARVRHHYPHLALRPELVTVAEEVPGRAEEAAAQFGFASTTRDW 66
Query: 57 RELIKEG-VDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNV 115
RE+ + V AVSI P LHRE+ + + VEKP+ S + A+ + A V
Sbjct: 67 REVAADPRVHAVSITAPNFLHREIAVAMAGAGKHIWVEKPVGLSSDDARAVADAVSGAGV 126
Query: 116 VLMVGHVERFNPAVLKLKETIERGMLGEIV--------TMTAKRVGPMVTRI----SDVG 163
VG R PAV + I G +G + A G + R G
Sbjct: 127 QGAVGFNYRNAPAVETARRLIAAGEIGTVTHARLRFFSDYAAHPEGALTWRYERERGGSG 186
Query: 164 VIIDLAVHDIDVMSF-------LTTSRVIEVYAKARNVK-------------HPAKVEDY 203
V+ DLA H D+ F LT + V +AR P + EDY
Sbjct: 187 VLGDLASHGADLARFLLGDIASLTADTAVFVPERARPASATAGHARATGGEPGPVENEDY 246
Query: 204 ALILLSFENGANGIIETNRLTPHKTRT--LNVVGTEGIAYLDY 244
LL F +GA G++E R++ + V GT G + D+
Sbjct: 247 VSCLLRFASGARGVLEACRVSVGEQNNYGFEVHGTTGAVFWDF 289
>gb|AAD03557.1| (AF095748) phthalate dihydrodiol dehydrogenase [Burkholderia
cepacia]
Length = 391
Score = 78.8 bits (191), Expect = 7e-14
Identities = 58/231 (25%), Positives = 95/231 (41%), Gaps = 13/231 (5%)
Query: 1 MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELI 60
+R+GV G+G+ + + ++ +V+L+ D E ++ A F + D EL
Sbjct: 6 LRIGVAGLGRA---FSLMLPTFLRDSRVQLVAACDPRDEARRQFAADFAAPTYADVAELA 62
Query: 61 KE-GVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMV 119
+ V+ + +A P H + T VLVEKP+A + +I A + NV L+V
Sbjct: 63 NDPNVEIIYVASPHQFHAQHTEIAAAKGKHVLVEKPMALAAADCDRMIAACRAANVHLIV 122
Query: 120 GHVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTR---------ISDVGVIIDLAV 170
GH F+ L+ +E I G G + + A + R G + A
Sbjct: 123 GHCHSFDTPYLRTRELISLGDFGAVKMIQAVNYTDYLYRPRRPEELATAEGGGAVFSQAA 182
Query: 171 HDIDVMSFLTTSRVIEVYAKARNVKHPAKVEDYALILLSFENGANGIIETN 221
H +D++ L SR + A E L+ FENGA + N
Sbjct: 183 HQVDIVRMLAGSRATRLRASVGRWDPSRPTEGAYSALIWFENGAYASLSYN 233
>sp|P26935|MI2D_BACSU MYO-INOSITOL 2-DEHYDROGENASE >gi|80338|pir||JH0511 myo-inositol
2-dehydrogenase (EC 1.1.1.18) iolG - Bacillus subtilis
>gi|143086|gb|AAA22543.1| (M76431) inositol
dehydrogenase [Bacillus subtilis]
>gi|709987|dbj|BAA03296.1| (D14399) myo-inositol
dehydrogenase [Bacillus subtilis]
>gi|2636516|emb|CAB16006.1| (Z99124) myo-inositol
2-dehydrogenase [Bacillus subtilis]
Length = 344
Score = 77.3 bits (187), Expect = 2e-13
Identities = 66/253 (26%), Positives = 122/253 (48%), Gaps = 16/253 (6%)
Query: 1 MRVGVVGVGKMGYHHA-RIYSELAKEGKVELIGVADINFERAKEVAETFKTRAF---KDY 56
+R+GV+G G +G H RI ++L+ E++ V D+N E A++V E ++ A D
Sbjct: 3 LRIGVIGTGAIGKEHINRITNKLSG---AEIVAVTDVNQEAAQKVVEQYQLNATVYPNDD 59
Query: 57 RELIKEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNV- 115
L E VDAV + H + I+ + V EKP+A + E I++ K+
Sbjct: 60 SLLADENVDAVLVTSWGPAHESSVLKAIKAQKYVFCEKPLATTAEGCMRIVEEEIKVGKR 119
Query: 116 VLMVGHVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMV--TRISDVGVIIDLAVHDI 173
++ VG + R++ ++LKE ++ + GE + + P V +D+ V +D VH+I
Sbjct: 120 LVQVGFMRRYDSGYVQLKEALDNHVNGEPLMIHCAHRNPTVGDNYTTDMAV-VDTLVHEI 178
Query: 174 DVMSFLTTS--RVIEVYAKARNVKHPAKVEDYALILLSFENG--ANGIIETNRLTPHKTR 229
DV+ +L ++V ++ ++D ++++ + G N I N + +
Sbjct: 179 DVLHWLVNDDYESVQVIYPKKSKNALPHLKDPQIVVIETKGGIVINAEIYVNCKYGYDIQ 238
Query: 230 TLNVVGTEGIAYL 242
+VG +GI L
Sbjct: 239 -CEIVGEDGIIKL 250
>gb|AAC01706.1| (AF040570) unknown [Amycolatopsis mediterranei]
Length = 342
Score = 76.9 bits (186), Expect = 3e-13
Identities = 73/289 (25%), Positives = 121/289 (41%), Gaps = 34/289 (11%)
Query: 40 RAKEVAETFKTRAFKDYRELIKEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAES 99
R++E+A F +A E + +G DAV I PT+ H E+ + I V V+ EKP+A S
Sbjct: 52 RSRELAAEFGAKAAGSLEEAL-DGADAVDICTPTASHHEIALTAIAAGVGVVCEKPLAAS 110
Query: 100 IESAQEIIKAAKKMNVVLMVGHVERFNPAVLKLKETIERGMLGE----IVTMTAKRVGPM 155
E A+EI+ AA++ V L H RF +L E + G LGE + +A P
Sbjct: 111 AEEAEEIVTAAERAGVRLYAAHDVRFAAPYARLHELVASGRLGEGALGRFSFSAYHPRPW 170
Query: 156 VTRIS--DVGVIIDLAVHDIDVMSFLTTSRVIEVYAKAR-NVKHPA---KVEDYALILLS 209
S G++ D +H D+ ++ V+ V+A + ++ PA V +L
Sbjct: 171 TGHASARSGGILTDQLLHGADLAHWV-FGDVVRVHACYQGDIATPAPEGAVATGTAVLTH 229
Query: 210 FENGANGIIETNRLTPHK--TRTLNVVGTEGIAYLDYINQELTLYNEEWIYKAKI----- 262
+ ++ TP +V GT G Y+ EW + ++
Sbjct: 230 ASGAISQVVSRWTATPRPPVRVAFHVSGTGG----------SVSYDSEWPQEVRVVDGGA 279
Query: 263 -----NKEEPLKLEIEHFLECVKEGKKPLVGGEEGLHALKVAVKALESS 306
E+ F G +P +G ++ L A+++ A ES+
Sbjct: 280 GNFAYGGPSVFDTEMREFATAFAGGPEPRIGAKDALAAVRIIHAAAESA 328
>emb|CAC11395.1| (AL445063) glucose-fructose oxidoreductase related protein
[Thermoplasma acidophilum]
Length = 322
Score = 76.9 bits (186), Expect = 3e-13
Identities = 60/228 (26%), Positives = 106/228 (46%), Gaps = 21/228 (9%)
Query: 1 MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKT-RAFKDYREL 59
M + +VG G H RIYS+L + + + + + AK +E F+ + + +Y +
Sbjct: 1 MDIVLVGCKGFGKEHLRIYSKLGYD-----VSIVERDSNEAKRCSELFRVYKVYDNYEDA 55
Query: 60 IKEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMV 119
++ G + V + VP LH E+ ++++ +LVEKPI I+S +I+ A++ + LMV
Sbjct: 56 LRSGSNIVDLVVPDGLHYEMGSLALKSKKHLLVEKPITPDIDSGISLIQQAEESKLKLMV 115
Query: 120 GHVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTR-------ISDVGVIIDLAVHD 172
F+P+V + I G +G+ T+ + + + G++ID H
Sbjct: 116 AEQFYFDPSVNEAIRRINNGEIGKPHTVIVRHQSFRELKGWRNEKSMMGRGILIDEGTHY 175
Query: 173 IDVMSFLTTSRVIEVYAKARNVKHPA---KVEDYALILLSFENGANGI 217
ID T Y R+ H ED A + +FENG +G+
Sbjct: 176 ID-----TLLNFGGRYRSLRSFVHRTWDFLGEDTAEAVFNFENGMHGL 218
>pir||T36464 probable oxidoreductase - Streptomyces coelicolor
>gi|5824085|emb|CAB54161.1| (AL110470) putative
oxidoreductase [Streptomyces coelicolor A3(2)]
Length = 417
Score = 76.1 bits (184), Expect = 5e-13
Identities = 65/287 (22%), Positives = 116/287 (39%), Gaps = 53/287 (18%)
Query: 1 MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKD--YRE 58
+RVGVVGVG+ A + + + + G ++ AD + ++ F Y
Sbjct: 12 LRVGVVGVGQ----RADMAALVNRSGAARIVSCADPDPRGREDARRLFGADVVVHDRYER 67
Query: 59 LIKEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLM 118
++ + +DAV + P LH E + F+ V+V VEKP+ ++ ++ AA + L
Sbjct: 68 MLDDELDAVFVLTPDHLHTEPALCFLAAGVAVFVEKPLTITVADCDALLMAAFRSRTRLY 127
Query: 119 VGHVERFNPAVLKLKETIERGMLGEIVTMTAKR-VGP---------MVTRISDVGVIIDL 168
VGH R P + +++E I+ G +G + + + VG R + G+++
Sbjct: 128 VGHNLRHLPVLRRMRELIDDGAVGRVRAVWCRHFVGHGGDFYFKDWHAQRANTTGLLLQK 187
Query: 169 AVHDIDVMSFL--------TTSRVIEVY-----------------------------AKA 191
HD+DV+ +L + VY +
Sbjct: 188 GAHDLDVVHWLAGGFSRNVVAQGALAVYGDNPRRATQETVPPGQRMPDWFDPEVWPPSAL 247
Query: 192 RNVKHPAKVEDYALILLSFENGANGIIETNRLTPHKTRTLNVVGTEG 238
R++ VED +++L +NG + TP R V+G EG
Sbjct: 248 RDLNPVVDVEDISMMLARLDNGVLASYQQCHFTPDYWRNYTVIGDEG 294
>pir||A71443 probable inositol 2-dehydrogenase - Arabidopsis thaliana
>gi|2245096|emb|CAB10518.1| (Z97343) inositol
2-dehydrogenase like protein [Arabidopsis thaliana]
>gi|7268489|emb|CAB78740.1| (AL161546) inositol
2-dehydrogenase like protein [Arabidopsis thaliana]
Length = 364
Score = 76.1 bits (184), Expect = 5e-13
Identities = 65/242 (26%), Positives = 119/242 (48%), Gaps = 26/242 (10%)
Query: 2 RVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFER---AKEVAETF--KTRAFKDY 56
+ G+VG+G MG H L +G + ++ +AD + A E+A++F + + F +
Sbjct: 11 KYGIVGIGMMGREHLINLHHLRDQG-LAVVCIADPHPPSQLLAIELAQSFGWELKVFSGH 69
Query: 57 RELIK-EGVDAVSIAVPTSLHREVTMDFIENEVS--VLVEKPIAESIESAQEIIKAAKK- 112
EL+K E D + ++ P H ++ MD I VLVEKP+ ++ +++++AAKK
Sbjct: 70 EELLKSELCDVIVVSSPNMTHHQILMDIINYSKPHHVLVEKPLCTTVADCKQVLEAAKKR 129
Query: 113 MNVVLMVGHVERFNPAVLKLKETIERGMLGEIVTMTAKRVG--PMVTRIS----DVGVII 166
++V+ VG R+ P V KL E ++ G V M A R P + ++ + ++
Sbjct: 130 SDMVVQVGLEYRYMPPVAKLIEQVKGRDFGN-VKMVAIREHRFPFLVKVGLNKMGLWTLV 188
Query: 167 DLAVHDIDVMSFLTTSRVIEVYAK-ARNVKHPAKVE--------DYALILLSFENGANGI 217
+ H D+M + + V A +V H +V D A +++ F+NG G+
Sbjct: 189 EKCCHFFDLMRLFAGANPVCVMASGGMDVNHKDEVYGGKVPDIIDNAYVIIEFDNGCRGM 248
Query: 218 IE 219
++
Sbjct: 249 LD 250
>gb|AAC71791.1| (M77665) qutH [Aspergillus nidulans]
Length = 398
Score = 74.9 bits (181), Expect = 1e-12
Identities = 68/258 (26%), Positives = 112/258 (43%), Gaps = 44/258 (17%)
Query: 5 VVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELIKE-- 62
+VG G +G HA+ + + + +LI D + A VAE+F + ++
Sbjct: 16 IVGAGLIGPRHAQ---SVQRHPRTQLIAFVDPS-PSAIPVAESFGVPCYDSITSMLDVVG 71
Query: 63 ----GVDAVSIAVPTSLHREVTMDFIENEV-SVLVEKPIAESIESAQEII---------- 107
DA ++ P H +VT+ +EN + ++L+EKPI++ +ESA+ ++
Sbjct: 72 KTTGKPDAAIVSTPNHTHVDVTLQLLENGIRNILLEKPISDDLESAEHLLATVKEQKCKD 131
Query: 108 -KAAKKMNVVLMVGHVERFNPAVLKLKETIERGMLGEIVTMT------------AKRVGP 154
K K + + +GH RFNP + K +E LG +V + A +G
Sbjct: 132 EKRGKDAKINIQIGHHRRFNPYIQTTKSLLETDSLGTVVAVNGLWTLLKPASYFAPPLGS 191
Query: 155 MVTRISDVGVIIDLAVHDIDVMSFLTTSRVIEVYAKA-------RNVKHPAKVEDYALIL 207
GV+ +HDIDV+ FL V VYA+ +N +H A E+ +
Sbjct: 192 WRADKKKGGVLGINLIHDIDVLQFL-FGPVSRVYAEGTLLQRMRQNPEHTA--EEGCAVT 248
Query: 208 LSFENGANGIIETNRLTP 225
L F +G G TP
Sbjct: 249 LRFASGIVGTFLICDATP 266
>emb|CAC12307.1| (AL445066) glucose-fructose oxidoreductase related protein
[Thermoplasma acidophilum]
Length = 321
Score = 74.9 bits (181), Expect = 1e-12
Identities = 62/255 (24%), Positives = 107/255 (41%), Gaps = 30/255 (11%)
Query: 1 MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTR-----AFKD 55
M+V ++G+ G H +S+L + ++ ER EV +R
Sbjct: 1 MKVNIIGLNGFGKRHIEAWSKLDVDIEIT---------ERKAEVVRDLLSRYDIVKVNSS 51
Query: 56 YRELIKEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNV 115
E + + +P +LH +VT+ + V+VEKPIA I A+E+I+ A +
Sbjct: 52 LEEAFNSDAEIFDLVLPHNLHHDVTVKSLAMGKHVMVEKPIATDISDAREMIRTAVQNRR 111
Query: 116 VLMVGHVERFNPAVLKLKETIERGMLGEIVTMTAK-------RVGPMVTRISDVGVIIDL 168
MV F+P+V K KE ++ G +G + T+ + I G +ID
Sbjct: 112 KFMVADQYYFDPSVWKAKEIMDSGKIGSVHTIIIRDQRKYNWHGWRSQASIMGGGPLIDG 171
Query: 169 AVHDIDVMSFLTTSRV---IEVYAKARNVKHPAKVEDYALILLSFENGANGII--ETNRL 223
+H ID M L + Y +++ P VE + F++G+NG+
Sbjct: 172 GIHFIDTMLNLAGEYISVRSNFYRSVASIEEPDTVE----AIFKFKDGSNGLFFYSWGYP 227
Query: 224 TPHKTRTLNVVGTEG 238
P + ++GT+G
Sbjct: 228 YPPSLPSFEIIGTDG 242
>pir||A69834 conserved hypothetical protein yhjJ - Bacillus subtilis
>gi|2226182|emb|CAA74472.1| (Y14081) hypothetical
protein [Bacillus subtilis] >gi|2633389|emb|CAB12893.1|
(Z99109) similar to hypothetical proteins [Bacillus
subtilis]
Length = 350
Score = 74.1 bits (179), Expect = 2e-12
Identities = 66/230 (28%), Positives = 108/230 (46%), Gaps = 23/230 (10%)
Query: 2 RVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELIK 61
++G++G G + HA S + EL+GV DIN + A+ +TF ++F++ ELI
Sbjct: 3 KIGIIGAGGIARAHATALSTIKN---AELVGVYDINQQNAESFVKTFGGKSFENVDELI- 58
Query: 62 EGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMVGH 121
+ + + +A P H+E + + VL EKP+A S+E A + A++++V +G
Sbjct: 59 DASEGLIVASPNFCHKEHALQALGKHKHVLCEKPMAISLEEASIMKDTAERLSVRASMGF 118
Query: 122 VERFNPAVLKLKETIERGMLGEIVTM-------TAKRVGPMVTR-----ISDVGVIIDLA 169
R+ V LK I LG I+++ +A R R G + DL
Sbjct: 119 NYRYLSYVNILKSLIINNELGNILSIKVHFKKNSALRRKKFTWRDDANSKKTSGSLGDLG 178
Query: 170 VHDIDVMSFLTTSRVIEVYAKAR---NVK----HPAKVEDYALILLSFEN 212
+H ID++ +L S I +A+ NVK V+DYA I N
Sbjct: 179 IHLIDMVWYLFESDFITESVRAKMNTNVKTKEDKQVLVDDYAEIYGQLRN 228
>emb|CAB02496.1| (Z80356) glucose-fructose oxidoreductase [Zymomonas mobilis]
Length = 433
Score = 73.4 bits (177), Expect = 3e-12
Identities = 77/334 (23%), Positives = 146/334 (43%), Gaps = 36/334 (10%)
Query: 5 VVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETF-----KTRAFKDYREL 59
+VG+GK + + ++E + N E+AK VA + K + ++ ++
Sbjct: 88 IVGLGKYALNQILPGFAGCQHSRIEAL--VSGNAEKAKIVAAEYGVDPRKIYDYSNFDKI 145
Query: 60 IKEG-VDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLM 118
K+ +DAV I +P SLH E + + V+ EKP+A S+ Q +I AAK N LM
Sbjct: 146 AKDPKIDAVYIILPNSLHAEFAIRAFKAGKHVMCEKPMATSVADCQRMIDAAKAANKKLM 205
Query: 119 VG---HVERFNPAVLKLKETIERGMLGEIVTMTAKRVGP--------MVTRISDVGVIID 167
+G H + N A +KL + G LG + T + + + ++ G ++D
Sbjct: 206 IGYRCHYDPMNRAAVKLIRENQLGKLGMVTTDNSDVMDQNDPAQQWRLRRELAGGGSLMD 265
Query: 168 LAVHDIDVMSFLTTSRVIEVYA---KARNVKHPAKVEDYALILLSFENGA--NGIIETNR 222
+ ++ ++ +L IEV A N + +VED + + F +GA +G +
Sbjct: 266 IGIYGLNGTRYLLGEEPIEVRAYTYSDPNDERFVEVEDRIIWQMRFRSGALSHGASSYST 325
Query: 223 LTPHKTRTLNVVGTEGIAYLD----YINQELTLY-----NEEWIYKAKINKEEPLKLEIE 273
T T +V G + + +D Y +++ N+ + + + +++
Sbjct: 326 TT---TSRFSVQGDKAVLLMDPATGYYQNLISVQTPGHANQSMMPQFIMPANNQFSAQLD 382
Query: 274 HFLECVKEGKKPLVGGEEGLHALKVAVKALESSK 307
H E V K GEEG+ +++ E+++
Sbjct: 383 HLAEAVINNKPVRSPGEEGMQDVRLIQAIYEAAR 416
>pdb|1OFG|A Chain A, Glucose-Fructose Oxidoreductase >gi|2098324|pdb|1OFG|B
Chain B, Glucose-Fructose Oxidoreductase
>gi|2098325|pdb|1OFG|C Chain C, Glucose-Fructose
Oxidoreductase >gi|2098326|pdb|1OFG|D Chain D,
Glucose-Fructose Oxidoreductase >gi|2098327|pdb|1OFG|E
Chain E, Glucose-Fructose Oxidoreductase
>gi|2098328|pdb|1OFG|F Chain F, Glucose-Fructose
Oxidoreductase
Length = 381
Score = 73.4 bits (177), Expect = 3e-12
Identities = 77/334 (23%), Positives = 146/334 (43%), Gaps = 36/334 (10%)
Query: 5 VVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETF-----KTRAFKDYREL 59
+VG+GK + + ++E + N E+AK VA + K + ++ ++
Sbjct: 36 IVGLGKYALNQILPGFAGCQHSRIEAL--VSGNAEKAKIVAAEYGVDPRKIYDYSNFDKI 93
Query: 60 IKEG-VDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLM 118
K+ +DAV I +P SLH E + + V+ EKP+A S+ Q +I AAK N LM
Sbjct: 94 AKDPKIDAVYIILPNSLHAEFAIRAFKAGKHVMCEKPMATSVADCQRMIDAAKAANKKLM 153
Query: 119 VG---HVERFNPAVLKLKETIERGMLGEIVTMTAKRVGP--------MVTRISDVGVIID 167
+G H + N A +KL + G LG + T + + + ++ G ++D
Sbjct: 154 IGYRCHYDPMNRAAVKLIRENQLGKLGMVTTDNSDVMDQNDPAQQWRLRRELAGGGSLMD 213
Query: 168 LAVHDIDVMSFLTTSRVIEVYA---KARNVKHPAKVEDYALILLSFENGA--NGIIETNR 222
+ ++ ++ +L IEV A N + +VED + + F +GA +G +
Sbjct: 214 IGIYGLNGTRYLLGEEPIEVRAYTYSDPNDERFVEVEDRIIWQMRFRSGALSHGASSYST 273
Query: 223 LTPHKTRTLNVVGTEGIAYLD----YINQELTLY-----NEEWIYKAKINKEEPLKLEIE 273
T T +V G + + +D Y +++ N+ + + + +++
Sbjct: 274 TT---TSRFSVQGDKAVLLMDPATGYYQNLISVQTPGHANQSMMPQFIMPANNQFSAQLD 330
Query: 274 HFLECVKEGKKPLVGGEEGLHALKVAVKALESSK 307
H E V K GEEG+ +++ E+++
Sbjct: 331 HLAEAVINNKPVRSPGEEGMQDVRLIQAIYEAAR 364
>sp|Q07982|GFO_ZYMMO GLUCOSE--FRUCTOSE OXIDOREDUCTASE PRECURSOR (GFOR)
>gi|95542|pir||A42289 glucose-fructose oxidoreductase
(EC 1.1.-.-) precursor - Zymomonas mobilis
>gi|155588|gb|AAA27690.1| (M97379) glucose-fructose
oxidoreductase [Zymomonas mobilis]
Length = 439
Score = 72.6 bits (175), Expect = 5e-12
Identities = 74/304 (24%), Positives = 133/304 (43%), Gaps = 33/304 (10%)
Query: 39 ERAKEVAETF-----KTRAFKDYRELIKEG-VDAVSIAVPTSLHREVTMDFIENEVSVLV 92
E+AK VA + K + ++ ++ K+ +DAV I +P SLH E + + V+
Sbjct: 119 EKAKIVAAEYGVDPRKIYDYSNFDKIAKDPKIDAVYIILPNSLHAEFAIRSFKAGKHVMC 178
Query: 93 EKPIAESIESAQEIIKAAKKMNVVLMVG---HVERFNPAVLKLKETIERGMLGEIVTMTA 149
EKP+A S+ Q +I AAK N LM+G H + N A +KL + G LG + T +
Sbjct: 179 EKPMATSVADCQRMIDAAKAANKKLMIGYRCHYDPMNRAAVKLIRENQLGKLGMVTTDNS 238
Query: 150 KRVGPMVTRISDV-------GVIIDLAVHDIDVMSFLTTSRVIEVYA---KARNVKHPAK 199
+ S V G ++D+ ++ ++ +L IEV A N + +
Sbjct: 239 DVMDQNDLHSSGVCVVNSGGGSLMDIGIYGLNGTRYLLGEEPIEVRAYTYSDPNDERFVE 298
Query: 200 VEDYALILLSFENGA--NGIIETNRLTPHKTRTLNVVGTEGIAYLD----YINQELTLY- 252
VED + + F +GA +G + T T +V G + + +D Y +++
Sbjct: 299 VEDRIIWQMRFRSGALSHGASSYSTTT---TSRFSVQGDKAVLLMDPATGYYQNLISVQT 355
Query: 253 ----NEEWIYKAKINKEEPLKLEIEHFLECVKEGKKPLVGGEEGLHALKVAVKALESSKK 308
N+ + + + +++H E V K GEEG+ +++ E+++
Sbjct: 356 PGHANQSMMPQFIMPANNQFSAQLDHLAEAVINNKPVRSPGEEGMQDVRLIQAIYEAART 415
Query: 309 DEVV 312
V
Sbjct: 416 GRAV 419
>pir||A72379 hypothetical protein TM0425 - Thermotoga maritima (strain MSB8)
>gi|4980931|gb|AAD35510.1|AE001721_9 (AE001721)
oxidoreductase, putative [Thermotoga maritima]
Length = 328
Score = 72.6 bits (175), Expect = 5e-12
Identities = 75/295 (25%), Positives = 140/295 (47%), Gaps = 31/295 (10%)
Query: 42 KEVAE-TFKTRAFKDYRELI-KEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAES 99
K ++E K + + ++ E++ KE D + I SL+ ++ ++ +E ++ VEKPIA +
Sbjct: 43 KAISEMNIKPKKYNNWWEMLEKEKPDILVINTVFSLNGKILLEALERKIHAFVEKPIATT 102
Query: 100 IESAQEIIKAAKKM--NVVLMVGHVERFNPAVLKLKETIERGMLGEI---VTMTAKRVGP 154
E ++I +K+ V R+ P L K+ + G +GEI T + ++G
Sbjct: 103 FEDLEKIRSVYQKVRNEVFFTAMFGIRYRPHFLTAKKLVSEGAVGEIRLVNTQKSYKLGQ 162
Query: 155 ----MVTRISDVGVIIDLAVHDIDVMSFLTTSRVIEVYA---KARNVKHPAKVEDYALIL 207
R + G I + +H ID + ++T + + VYA + N H ++E AL
Sbjct: 163 RPDFYKKRETYGGTIPWVGIHAIDWIHWITGKKFLSVYATHSRLHNSGH-GELETTALCH 221
Query: 208 LSFENGANGIIETNRLTP-----HKTRTLNVVGTEGIAYLDYINQELTLYNEEWIYKAKI 262
+ EN + + L P H + +VGT GI ++ IN+ + L +E K
Sbjct: 222 FTLENEVFASLSIDYLRPQGAPTHDDDRMRIVGTRGI--VEVINERVFLTDE------KG 273
Query: 263 NKEEPLKLE---IEHFLECVKEGKKPLVGGEEGLHALKVAVKALESSKKDEVVRV 314
++E PL + E FL ++ K +V E+ + ++A+KA S+ ++V +
Sbjct: 274 HREVPLVEKGQIFEDFLREIRGQGKCMVTPEDSILTTEIALKARLSADTGQIVLI 328
>pir||S56505 hypothetical 41.9K protein (leuX-fecE intergenic region) -
Escherichia coli >gi|537121|gb|AAA97176.1| (U14003)
ORF_o377 [Escherichia coli] >gi|1790731|gb|AAC77236.1|
(AE000498) putative dehydrogenase [Escherichia coli K12]
Length = 377
Score = 72.2 bits (174), Expect = 7e-12
Identities = 47/151 (31%), Positives = 73/151 (48%), Gaps = 6/151 (3%)
Query: 4 GVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELIKEG 63
GVVGVG G AR + + K+ + + E + +A + L+
Sbjct: 10 GVVGVGYFGAELAR-FMNMHDNAKITCV----YDPENGENIARELQCINMSSLDALVSSK 64
Query: 64 -VDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMVGHV 122
VD V +A P LH+E + +N+ V EKPIA S E +++KA K+ V M GH+
Sbjct: 65 LVDCVIVATPNYLHKEPVIKAAKNKKHVFCEKPIALSYEDCVDMVKACKEAGVTFMAGHI 124
Query: 123 ERFNPAVLKLKETIERGMLGEIVTMTAKRVG 153
F V ++ I+ G++GEI++ KR G
Sbjct: 125 MNFFNGVQYARKLIKEGVIGEILSCHTKRNG 155
>sp|P39353|YJHC_ECOLI HYPOTHETICAL 41.4 KD PROTEIN IN LEUX-FECE INTERGENIC REGION
Length = 372
Score = 72.2 bits (174), Expect = 7e-12
Identities = 47/151 (31%), Positives = 73/151 (48%), Gaps = 6/151 (3%)
Query: 4 GVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELIKEG 63
GVVGVG G AR + + K+ + + E + +A + L+
Sbjct: 5 GVVGVGYFGAELAR-FMNMHDNAKITCV----YDPENGENIARELQCINMSSLDALVSSK 59
Query: 64 -VDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMVGHV 122
VD V +A P LH+E + +N+ V EKPIA S E +++KA K+ V M GH+
Sbjct: 60 LVDCVIVATPNYLHKEPVIKAAKNKKHVFCEKPIALSYEDCVDMVKACKEAGVTFMAGHI 119
Query: 123 ERFNPAVLKLKETIERGMLGEIVTMTAKRVG 153
F V ++ I+ G++GEI++ KR G
Sbjct: 120 MNFFNGVQYARKLIKEGVIGEILSCHTKRNG 150
>pir||T50594 probable oxidoreductase [imported] - Streptomyces coelicolor
>gi|6469270|emb|CAB61731.1| (AL133220) putative
oxidoreductase. [Streptomyces coelicolor A3(2)]
Length = 351
Score = 72.2 bits (174), Expect = 7e-12
Identities = 72/248 (29%), Positives = 109/248 (43%), Gaps = 17/248 (6%)
Query: 1 MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKT-RAFKDYREL 59
+R G++ G M AR ++L E++ VA AK AE F RA+ + L
Sbjct: 9 VRWGILATGGMA---ARFTADLVDLPDAEVVAVASRTEASAKTFAERFGIPRAYGGWETL 65
Query: 60 IK-EGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLM 118
+ E VD V +A P S HR +E +VL EKP + A E++ A++ V LM
Sbjct: 66 ARDEDVDVVYVATPHSAHRTAAGLCLEAGRNVLCEKPFTLNAREAAELVALARENGVFLM 125
Query: 119 VGHVERFNPAVLKLKETIERGMLGEIVTMTAK--RVGPM--VTRISDV----GVIIDLAV 170
NP V +LKE + G +GE+ ++ A GP R+ D G ++DL V
Sbjct: 126 EAMWMYCNPLVRRLKELVADGAIGEVRSLQADFGLAGPFPAAHRLRDPAQGGGALLDLGV 185
Query: 171 HDIDVMSFLTTSRVIEVYAKARNVKHPAKVEDYALILLSFENGANGIIETNRLTPHKTRT 230
+ + L AR V V+ LLS+ N A I + +T +
Sbjct: 186 YPVSFAQLLLGE---PTDVAARAVLSEEGVDLQTGALLSYGNDALASIHCS-ITGGTPNS 241
Query: 231 LNVVGTEG 238
++ G+EG
Sbjct: 242 ASITGSEG 249
>sp|P77503|YCJS_ECOLI HYPOTHETICAL 38.7 KD PROTEIN IN PSPE-OMPG INTERGENIC REGION
>gi|7467124|pir||F64880 ycjS protein - Escherichia coli
>gi|1742152|dbj|BAA14890.1| (D90769) Rhizopine
catabolism protein MocA. [Escherichia coli]
>gi|1742160|dbj|BAA14897.1| (D90770) Rhizopine
catabolism protein MocA. [Escherichia coli]
>gi|1787574|gb|AAC74397.1| (AE000229) putative
dehydrogenase [Escherichia coli K12]
Length = 351
Score = 71.8 bits (173), Expect = 9e-12
Identities = 53/191 (27%), Positives = 90/191 (46%), Gaps = 15/191 (7%)
Query: 1 MRVGVVGVGKMGYH-HARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYREL 59
+RV ++G G++ HA Y +EL+ V D +A+ +AE + + D +
Sbjct: 10 LRVAIIGAGQVADKVHASYY---CTRNDLELVAVCDSRLSQAQALAEKYGNASVWDDPQA 66
Query: 60 IKEGV--DAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVL 117
+ V D VS+ P H E T+ +E V+ EKP A + E A+E+ A+K+ VL
Sbjct: 67 MLLAVKPDVVSVCSPNRFHYEHTLMALEAGCHVMCEKPPAMTPEQAREMCDTARKLGKVL 126
Query: 118 MVGHVERFNPAVLKLKETIERGMLGEIVTMTAKRV--------GPMVTR-ISDVGVIIDL 168
RF +L+E + G+LGEI TA+ + G + + G +ID+
Sbjct: 127 AYDFHHRFALDTQQLREQVTNGVLGEIYVTTARALRRCGVPGWGVFTNKELQGGGPLIDI 186
Query: 169 AVHDIDVMSFL 179
+H +D ++
Sbjct: 187 GIHMLDAAMYV 197
>pir||G72391 conserved hypothetical protein - Thermotoga maritima (strain MSB8)
>gi|4980813|gb|AAD35400.1|AE001713_4 (AE001713)
conserved hypothetical protein [Thermotoga maritima]
Length = 328
Score = 71.0 bits (171), Expect = 2e-11
Identities = 75/298 (25%), Positives = 125/298 (41%), Gaps = 25/298 (8%)
Query: 1 MRVGVVGVGKMGYH-HARIYSELAKEGKVELIGVADINFERAKEVAETFKTRA-FKDYRE 58
+R+G+VG G H L+ E+ V A+E A+ A F Y E
Sbjct: 7 IRLGIVGCGIAARELHLPALKNLSH--LFEITAVTSRTRSHAEEFAKMVGNPAVFDSYEE 64
Query: 59 LIKEG-VDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVL 117
L++ G VDAV + +P L+ + V V+ EKPI+ +E+ +++++ ++K +
Sbjct: 65 LLESGLVDAVDLTLPVELNLPFIEKALRKGVHVICEKPISTDVETGKKVVELSEKSEKTV 124
Query: 118 MVGHVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTRISDV------------GVI 165
+ R PA K KE +E G +G+ V M + M V G +
Sbjct: 125 YIAENFRHVPAFWKAKELVESGAIGDPVFMNWQIWVGMDENNKYVHTDWRKKPKHVGGFL 184
Query: 166 IDLAVHDIDVMSFLTTSRVIEVYAKARNVKHPAKVEDYALILLSFENGANGIIETNRLTP 225
D VH M L + + A A+++ D+ + FENG G +
Sbjct: 185 SDGGVHHAAAMR-LILGEIEWISAVAKDLSPLLGGMDFLSSIFEFENGTVGNYTISYSLK 243
Query: 226 HKTRTLNVVGTEGIAYLDYINQELTLYNEEWIYKAKINKEEPLKLEIEHFLECVKEGK 283
R + GT+G + + + + NEE + K+ +E + E E F + V EGK
Sbjct: 244 GNER-FEITGTKGKISISW---DKIVLNEE---EMKVPQENSYQKEFEDFYQVVAEGK 294
>gb|AAK43115.1| Dehydrogenase, putative [Sulfolobus solfataricus]
Length = 319
Score = 70.6 bits (170), Expect = 2e-11
Identities = 85/324 (26%), Positives = 134/324 (41%), Gaps = 28/324 (8%)
Query: 1 MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRA-FKDYREL 59
M++ VVG G H R ++ +E V N E+A+E + F F Y ++
Sbjct: 1 MKIAVVGCDGFGKVHLRAMRNISG---IEYY-VFSRNEEKARECMKEFNAEGYFTRYEDV 56
Query: 60 IKEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMV 119
IK VD V + V H + + ++ +++EKPIA +IE A +I +K MV
Sbjct: 57 IKSNVDIVDLLVSHDQHYPMGVMAMKAGKHLMLEKPIARTIEEAMGLINTSKDTKRKFMV 116
Query: 120 GHVERFNPAVLKLKETIER-GMLGEIVTMTAKRVGPMVTRISDV----GVIIDLAVHDID 174
F +V K KE + R G L I+ + P R G +ID VH ID
Sbjct: 117 LEQFYFESSVRKAKELLPRLGNLSLIIVRSIHLYQPKGWRREKEKMGGGALIDGGVHFID 176
Query: 175 VMSFLTTSRVIEVYAKARNV--KHPAKV--EDYALILLSFENGANGIIETNRLTPH--KT 228
+ L Y R V K+ + + ED L L F G G++ + TP+ K
Sbjct: 177 TLLNLGGE-----YESVRGVCGKYFSGIEGEDLTLATLRFRKGHLGLLMYSWTTPNPPKV 231
Query: 229 RTLNVVGTEGIAYLDYINQ-------ELTLYNEEWIYKAKINKEEPLKLEIEHFLECVKE 281
+ G G D + +L L + + ++ K P++ EI F++ VK
Sbjct: 232 PAFEIYGENGSIIEDPNTRVMGKAYGDLILNVDGKEERIEVEKVNPIEEEIRGFVKAVKN 291
Query: 282 GKKPLVGGEEGLHALKVAVKALES 305
+ + E L LK + +S
Sbjct: 292 NTEVPMPPEIALRDLKAVLDIYKS 315
>dbj|BAA83485.1| (AB021928) dimeric dihydrodiol dehydrogenase [Oryctolagus
cuniculus]
Length = 329
Score = 70.2 bits (169), Expect = 3e-11
Identities = 69/276 (25%), Positives = 128/276 (46%), Gaps = 23/276 (8%)
Query: 29 ELIGVADINFERAKEVAETFKT-RAFKDYRELIKE-GVDAVSIAVPTSLHREVTMDFIEN 86
+++ VA + RA+E A T +A+ Y EL K+ V+ I H+ + F+
Sbjct: 24 QVVAVAARDLRRAEEFARTHGIPKAYGSYEELAKDPDVEVAYIGTQHPQHKAAVLLFLAA 83
Query: 87 EVSVLVEKPIAESIESAQEIIKAAKKMNVVLMVGHVERFNPAVLKLKETIERGMLGEIVT 146
+VL EKP+ + +E++ A+ + LM R PAV LK + +G LG++
Sbjct: 84 GKAVLCEKPLGVNAAEVREMVAEARSRGLFLMEAIWTRCFPAVDALKSLLAQGALGDLRV 143
Query: 147 MTAKRVGPMVTRI-------SDVGVIIDLAVHDIDVMSFLTTSRVIEVYAKARNVKHPAK 199
A+ G +T++ G ++DL ++ + +S + + E + A ++
Sbjct: 144 ARAE-FGENLTQVLRSVDWAQAGGGLLDLGIYCVQFISMVFGGQKPEKIS-AVGRRYETG 201
Query: 200 VEDYALILLSFENGANGIIETNRLTPHKTRTLNVVGTEGIAYL---DYINQELTLYNE-- 254
V+D +LL + G +G T ++ + T +V GT+GIA L + EL + E
Sbjct: 202 VDDTVTVLLQYPGGVHGSF-TCSISSKLSNTCSVSGTKGIAQLLEPCWCPTELVVNKERK 260
Query: 255 EWIYKAKINKE------EPLKLEIEHFLECVKEGKK 284
E+ + NK+ + E +H +C+++G K
Sbjct: 261 EFPLAPEENKKFNYRNGMGMSYEAQHVRDCLRKGLK 296
>dbj|BAB07562.1| (AP001520) oxidoreductase [Bacillus halodurans]
Length = 334
Score = 69.9 bits (168), Expect = 4e-11
Identities = 76/329 (23%), Positives = 138/329 (41%), Gaps = 32/329 (9%)
Query: 1 MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADIN-FERAKEVAETFKT-RAFKDYRE 58
+R G++G G ++ + + E++ V+ N E+A A+ + + Y +
Sbjct: 5 VRWGILGTA--GIAKKQLIPAIKRASNAEVVAVSSRNDMEKANCYADECDIPKRYARYED 62
Query: 59 LIKE-GVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVL 117
L+ + +DAV I +P LH E+ VL EKP A + A+E++ A VV
Sbjct: 63 LLNDPDIDAVYIPLPNHLHLTWAKKAAEHGKHVLCEKPAALTAAEAKEMVDACAAHGVVF 122
Query: 118 MVGHVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTRISDV--------GVIIDLA 169
M + +F+P ++K I+ G +GE+ + + + +++ G + D+
Sbjct: 123 MEAFMYQFHPQHGEVKRLIDSGKIGEVRLIRSNFSFQLPLEANNIRLNREMGGGSLYDVG 182
Query: 170 VHDIDVMSFLTTSRVIEVYAKARNVKHPAKVEDYALI-LLSFENGANGIIETNRLTPHKT 228
+ I + +LT + Y HP D + +L E G + T+
Sbjct: 183 CYCIHLTRYLTGKEPVHAY--GTGYLHPELGVDTSFTGVLQMEGGVTSVF-TSSFEQPAD 239
Query: 229 RTLNVVGTEGIAYLDYI-----NQELTLYNEEWIYKAKINKEEPL-------KLEIEHFL 276
+ VVGTEG + Y +Q+ T I + +EE L +L++EH
Sbjct: 240 DSYEVVGTEGTIIVPYAFRPDKHQDGT---GVIIVRTSDGREETLSVQGDQYRLQVEHVS 296
Query: 277 ECVKEGKKPLVGGEEGLHALKVAVKALES 305
+ + G L GEE ++ + V L S
Sbjct: 297 DAILNGTPLLYPGEETVNNMSVVEACLHS 325
>pir||A82502 oxidoreductase, Gfo/Idh/MocA family VCA0099 [imported] - Vibrio
cholerae (group O1 strain N16961)
>gi|9657485|gb|AAF96013.1| (AE004352) oxidoreductase,
Gfo/Idh/MocA family [Vibrio cholerae]
Length = 346
Score = 69.5 bits (167), Expect = 5e-11
Identities = 82/341 (24%), Positives = 152/341 (44%), Gaps = 36/341 (10%)
Query: 8 VGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKD--YRELIKEGVD 65
VG +GY ++ L +E + ++ I+ + + V E + A+ D R + + VD
Sbjct: 8 VGVIGYGYSAKTFHLPFIDTLESLTLSAISSSQQQVVQEDWPQIAYFDSAQRLITESDVD 67
Query: 66 AVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMVGHVERF 125
V I P ++H + +E+ V+VEKP IE + +I+ A++ ++L V H R+
Sbjct: 68 LVIITAPNNVHFPLAKLALEHGKHVIVEKPFVTQIEQGRTLIELARQQGLLLSVFHNRRW 127
Query: 126 NPAVLKLKETIERGMLGEIVTMTA--KRVGPMVTR------ISDVGVIIDLAVHDIDVMS 177
+ L +K+ IE+G LG++ + R P+V + G++ DLA H +D +
Sbjct: 128 DGDFLTVKKLIEQGQLGDVKVFESHFDRYRPVVRQRWREQAQEGGGILFDLAPHLLD-QA 186
Query: 178 FLTTSRVIEVYAKARNVKHPAKVEDYALILLSFENGANGIIETNRLTPHKTRTLNVVGTE 237
+ + A R ++ A DY + L + + N +P V+G+
Sbjct: 187 LVLFGLPQSLSADCRMMRPDATTLDYFDLQLYYPQHVVR-LHANLYSPEPNVRYQVLGSL 245
Query: 238 GIAYLDY--INQELTL------YNEEW----------IYKAKINKEEPLKL-EIEHF--- 275
G Y+ Y QE L + +W +Y A+ N+ +L +H+
Sbjct: 246 G-KYVKYGLDPQEDRLKAGERPTHPQWSQEMPEQYGILYHAEGNENVITELGGYQHYFTQ 304
Query: 276 -LECVKEGKKPLVGGEEGLHALKVAVKALESSKKDEVVRVS 315
+E ++ G V E L ++++ ALESS K + + V+
Sbjct: 305 VVEAIRNGASNPVSAESALQSIQLIELALESSAKGQRLAVT 345
>dbj|BAA83486.1| (AB021929) dimeric dihydrodiol dehydrogenase [Sus scrofa]
Length = 335
Score = 68.7 bits (165), Expect = 8e-11
Identities = 74/311 (23%), Positives = 131/311 (41%), Gaps = 38/311 (12%)
Query: 1 MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKT-RAFKDYREL 59
+R G+V G + + L + +++ VA + RAKE A +A+ Y EL
Sbjct: 3 LRWGIVSAGLISSDFTTVL-RLLPRSEHQVVAVAARDLSRAKEFARKHDIPKAYGSYEEL 61
Query: 60 IKE-GVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLM 118
K+ V+ I H+ + + +VL EKP+ + +E++ A+ + LM
Sbjct: 62 AKDPNVEVAYIGTQHPQHKATVLLCLAAGKAVLCEKPMGVNAAEVREMVAEARSRGLFLM 121
Query: 119 VGHVERFNPAVLKLKETIERGMLGEIVTMTAK------RVGPMVTRISDVGVIIDLAVHD 172
RF PAV L+ + + LG++ + A V V G ++DL ++
Sbjct: 122 EAIWTRFFPAVEALRSVLAQETLGDLRVVQANFGKSIANVPRSVDWAQAGGSLLDLGIYC 181
Query: 173 IDVMSFLTTSRVIEVYAKARNVKHPAKVEDYALILLSFENGANGIIETNRLTPHKTRTLN 232
+ +S + + E + A ++ V+D +LL + G G T +T + T++
Sbjct: 182 LQFISMVYGGQKPEKIS-AVGRRYETGVDDTVSVLLQYPGGVQGSF-TCSITSQLSNTVS 239
Query: 233 VVGTEGIAYL---DYINQELTLYNEEWIYKAKINKEEPLK----------------LEIE 273
V GT+G+A + + EL + E +KE PL E +
Sbjct: 240 VSGTKGMAQILDPCWCPTELVVKGE--------HKEFPLPSAPGEEFNYTNGMGMCYEAK 291
Query: 274 HFLECVKEGKK 284
H EC+K+G K
Sbjct: 292 HVRECLKKGLK 302
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.317 0.135 0.366
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 102769935
Number of Sequences: 2977
Number of extensions: 3979579
Number of successful extensions: 20832
Number of sequences better than 1.0e-10: 60
Number of HSP's better than 0.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 52
Number of HSP's that attempted gapping in prelim test: 20729
Number of HSP's gapped (non-prelim): 61
length of query: 315
length of database: 189,106,746
effective HSP length: 61
effective length of query: 254
effective length of database: 152,599,039
effective search space: 38760155906
effective search space used: 38760155906
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.6 bits)
S2: 165 (68.7 bits)