BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB0775 (PAB0775) DE:NADH-DEPENDENT DEHYDROGENASE HOMOLOG.
         (315 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||E75096 NADH-dependent dehydrogenase homolog. PAB0775 - Pyro...   615  e-175
pir||H69216 3-chlorobenzoate-3,4-dioxygenase dyhydrogenase relat...   266  2e-70
pir||S76068 hypothetical protein - Synechocystis sp. (strain PCC...   215  5e-55
sp|P40332|YISS_BACSU HYPOTHETICAL 37.5 KD PROTEIN IN DEGA-NPRB I...   136  2e-31
pir||A75025 NADH-dependent dyhydrogenase related protein PAB1138...   132  6e-30
pir||D71201 hypothetical protein PH1881 - Pyrococcus horikoshii ...   130  2e-29
pir||D72381 dehydrogenase - Thermotoga maritima (strain MSB8) >g...   129  3e-29
gb|AAK43117.1| Dehydrogenase, putative [Sulfolobus solfataricus]      129  3e-29
dbj|BAB04967.1| (AP001511) NADH-dependent dyhydrogenase [Bacillu...   129  5e-29
sp|O05389|YRBE_BACSU HYPOTHETICAL 37.8 KDA PROTEIN IN CSBX-NADA ...   124  1e-27
pir||B72359 lipopolysaccharide biosynthesis protein BplA - Therm...   123  2e-27
pir||B75025 NADH-dependent dyhydrogenase related protein PAB1139...   122  7e-27
pir||E71201 probable glucose-fructose oxidoreductase - Pyrococcu...   121  9e-27
pir||A81396 hypothetical protein Cj0504c [imported] - Campylobac...   115  5e-25
gb|AAK43113.1| Dehydrogenase, putative [Sulfolobus solfataricus]      108  7e-23
dbj|BAB05884.1| (AP001514) unknown conserved protein [Bacillus h...   107  2e-22
pir||A83617 probable oxidoreductase PA0237 [imported] - Pseudomo...   102  4e-21
dbj|BAB05939.1| (AP001514) dehydrogenase [Bacillus halodurans]        102  5e-21
gb|AAK43149.1| Dehydrogenase, putative [Sulfolobus solfataricus]       98  2e-19
gb|AAC31183.1| (AF076240) putative NADH-inositol dehydrogenase M...    96  5e-19
emb|CAB88961.1| (AL353864) putative oxidoreductase. [Streptomyce...    94  1e-18
sp|P49307|MOCA_RHIME RHIZOPINE CATABOLISM PROTEIN MOCA >gi|21208...    94  3e-18
pir||B75475 glucose-fructose oxidoreductase - Deinococcus radiod...    93  3e-18
dbj|BAB04429.1| (AP001509) unknown conserved protein [Bacillus h...    92  8e-18
gb|AAC23913.1| (AF039207) NADH-dependent dehydrogenase homolog [...    92  1e-17
emb|CAB60174.1| (AL132824) putative dehydrogenase [Streptomyces ...    91  2e-17
sp|O68965|MI2D_RHIME MYO-INOSITOL 2-DEHYDROGENASE >gi|3088561|gb...    89  9e-17
sp|Q05184|PHT4_PSEPU PUTATIVE 4,5,-DIHYDROXYPHTHALATE DEHYDROGEN...    85  1e-15
sp|Q54728|YJHC_STRPN HYPOTHETICAL PROTEIN IN NANB 3'REGION (ORF-...    85  1e-15
emb|CAC11912.1| (AL445065) hypothetical protein [Thermoplasma ac...    83  5e-15
gb|AAG09709.1|AF218837_4 (AF218837) unknown [Pasteurella multocida]    82  6e-15
sp|P09400|STRI_STRGR STREPTOMYCIN BIOSYNTHESIS PROTEIN STRI >gi|...    82  6e-15
pir||S70672 dehydrogenase homolog - Bordetella pertussis >gi|992...    82  6e-15
dbj|BAB05940.1| (AP001514) unknown conserved protein [Bacillus h...    82  8e-15
dbj|BAB06035.1| (AP001515) myo-inositol 2-dehydrogenase [Bacillu...    82  8e-15
gb|AAD51832.1|AF175299_7 (AF175299) ThuB [Sinorhizobium meliloti]      81  1e-14
emb|CAB88965.1| (AL353864) putative oxidoreductase. [Streptomyce...    79  6e-14
gb|AAD03557.1| (AF095748) phthalate dihydrodiol dehydrogenase [B...    79  7e-14
sp|P26935|MI2D_BACSU MYO-INOSITOL 2-DEHYDROGENASE >gi|80338|pir|...    77  2e-13
gb|AAC01706.1| (AF040570) unknown [Amycolatopsis mediterranei]         77  3e-13
emb|CAC11395.1| (AL445063) glucose-fructose oxidoreductase relat...    77  3e-13
pir||T36464 probable oxidoreductase - Streptomyces coelicolor >g...    76  5e-13
pir||A71443 probable inositol 2-dehydrogenase - Arabidopsis thal...    76  5e-13
gb|AAC71791.1| (M77665) qutH [Aspergillus nidulans]                    75  1e-12
emb|CAC12307.1| (AL445066) glucose-fructose oxidoreductase relat...    75  1e-12
pir||A69834 conserved hypothetical protein yhjJ - Bacillus subti...    74  2e-12
emb|CAB02496.1| (Z80356) glucose-fructose oxidoreductase [Zymomo...    73  3e-12
pdb|1OFG|A Chain A, Glucose-Fructose Oxidoreductase >gi|2098324|...    73  3e-12
sp|Q07982|GFO_ZYMMO GLUCOSE--FRUCTOSE OXIDOREDUCTASE PRECURSOR (...    73  5e-12
pir||A72379 hypothetical protein TM0425 - Thermotoga maritima (s...    73  5e-12
pir||S56505 hypothetical 41.9K protein (leuX-fecE intergenic reg...    72  7e-12
sp|P39353|YJHC_ECOLI HYPOTHETICAL 41.4 KD PROTEIN IN LEUX-FECE I...    72  7e-12
pir||T50594 probable oxidoreductase [imported] - Streptomyces co...    72  7e-12
sp|P77503|YCJS_ECOLI HYPOTHETICAL 38.7 KD PROTEIN IN PSPE-OMPG I...    72  9e-12
pir||G72391 conserved hypothetical protein - Thermotoga maritima...    71  2e-11
gb|AAK43115.1| Dehydrogenase, putative [Sulfolobus solfataricus]       71  2e-11
dbj|BAA83485.1| (AB021928) dimeric dihydrodiol dehydrogenase [Or...    70  3e-11
dbj|BAB07562.1| (AP001520) oxidoreductase [Bacillus halodurans]        70  4e-11
pir||A82502 oxidoreductase, Gfo/Idh/MocA family VCA0099 [importe...    69  5e-11
dbj|BAA83486.1| (AB021929) dimeric dihydrodiol dehydrogenase [Su...    69  8e-11

>pir||E75096 NADH-dependent dehydrogenase homolog. PAB0775 - Pyrococcus abyssi
           (strain Orsay) >gi|5458586|emb|CAB50074.1| (AJ248286)
           NADH-DEPENDENT DEHYDROGENASE HOMOLOG. [Pyrococcus
           abyssi]
           Length = 315
           
 Score =  615 bits (1569), Expect = e-175
 Identities = 315/315 (100%), Positives = 315/315 (100%)

Query: 1   MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELI 60
           MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELI
Sbjct: 1   MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELI 60

Query: 61  KEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMVG 120
           KEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMVG
Sbjct: 61  KEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMVG 120

Query: 121 HVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTRISDVGVIIDLAVHDIDVMSFLT 180
           HVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTRISDVGVIIDLAVHDIDVMSFLT
Sbjct: 121 HVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTRISDVGVIIDLAVHDIDVMSFLT 180

Query: 181 TSRVIEVYAKARNVKHPAKVEDYALILLSFENGANGIIETNRLTPHKTRTLNVVGTEGIA 240
           TSRVIEVYAKARNVKHPAKVEDYALILLSFENGANGIIETNRLTPHKTRTLNVVGTEGIA
Sbjct: 181 TSRVIEVYAKARNVKHPAKVEDYALILLSFENGANGIIETNRLTPHKTRTLNVVGTEGIA 240

Query: 241 YLDYINQELTLYNEEWIYKAKINKEEPLKLEIEHFLECVKEGKKPLVGGEEGLHALKVAV 300
           YLDYINQELTLYNEEWIYKAKINKEEPLKLEIEHFLECVKEGKKPLVGGEEGLHALKVAV
Sbjct: 241 YLDYINQELTLYNEEWIYKAKINKEEPLKLEIEHFLECVKEGKKPLVGGEEGLHALKVAV 300

Query: 301 KALESSKKDEVVRVS 315
           KALESSKKDEVVRVS
Sbjct: 301 KALESSKKDEVVRVS 315


>pir||H69216 3-chlorobenzoate-3,4-dioxygenase dyhydrogenase related protein -
           Methanobacterium thermoautotrophicum (strain Delta H)
           >gi|2621968|gb|AAB85373.1| (AE000863)
           3-chlorobenzoate-3,4-dioxygenase dyhydrogenase related
           protein [Methanobacterium thermoautotrophicum]
           Length = 318
           
 Score =  266 bits (673), Expect = 2e-70
 Identities = 139/316 (43%), Positives = 208/316 (64%), Gaps = 5/316 (1%)

Query: 1   MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELI 60
           + VGV+GVG MGY+HAR+Y  L       L+ V+DI     ++VA  + T  + DY  L+
Sbjct: 4   INVGVIGVGAMGYNHARVYYRLKN---ANLMAVSDIMKGTLQKVANKYDTVGYVDYENLL 60

Query: 61  K-EGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMV 119
           +   ++ VS+ VPT+ H  V MD +E++  VLVEKPIA ++E A++++K A+K  + L  
Sbjct: 61  EIPEIEVVSVCVPTTHHYNVVMDALEHDKHVLVEKPIAFTLEEAEDMVKTARKKGLKLGT 120

Query: 120 GHVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTRISDVGVIIDLAVHDIDVMSFL 179
           GHVERFNPAV K KE IE  ++G++V+ +AKRVGP   RI DVGV IDLA+HD+DVM +L
Sbjct: 121 GHVERFNPAVQKAKELIENDVIGDVVSASAKRVGPFPPRIKDVGVTIDLAIHDLDVMHYL 180

Query: 180 TTSRVIEVYAKARNVKHPAKVEDYALILLSFENGANGIIETNRLTPHKTRTLNVVGTEGI 239
            +  V EVYA   ++    + ED+A I+  F++G  GI+E N LTP+K R L + GT+GI
Sbjct: 181 FSEPVAEVYAVMGSILEKCEYEDHAEIMTKFKSGITGILEVNWLTPYKRRKLAITGTDGI 240

Query: 240 AYLDYINQELTLYNEEWIYKAKINKEEPLKLEIEHFLECVKEGKKPLVGGEEGLHALKVA 299
             +DYI+Q L +Y  ++     I  EEPLK EI+ FL  V   ++P + GE+G++AL+  
Sbjct: 241 INVDYIDQRLDVYG-KFAQDVDIKHEEPLKNEIKSFLMSVINDEEPEITGEDGIYALRTV 299

Query: 300 VKALESSKKDEVVRVS 315
           + A++S+++   V+V+
Sbjct: 300 LAAMKSAREHRPVKVN 315


>pir||S76068 hypothetical protein - Synechocystis sp. (strain PCC 6803)
           >gi|1001423|dbj|BAA10046.1| (D63999) hypothetical
           protein [Synechocystis sp.]
           Length = 364
           
 Score =  215 bits (542), Expect = 5e-55
 Identities = 117/316 (37%), Positives = 183/316 (57%), Gaps = 25/316 (7%)

Query: 1   MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELI 60
           +R+GV+GVG MG HH R+ S L K+  VE +G+AD+N ER  + A  ++   F+DY+E++
Sbjct: 24  IRIGVIGVGNMGQHHTRVLS-LMKD--VEFVGIADVNVERGLDTASKYRVHFFEDYQEML 80

Query: 61  KEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMVG 120
              VDAV +AVPT LH +V M+ ++N V  L+EKPIA SI  A+ ++ AA   N +L VG
Sbjct: 81  PH-VDAVCVAVPTRLHHDVGMNCLQNNVHTLIEKPIAASIAEAESLVNAAADANCILQVG 139

Query: 121 HVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTRISDVGVIIDLAVHDIDVMSFLT 180
           H+ERFNPA L+L + ++     E++ + A R+ P   R +DV V++DL +HDID++  L 
Sbjct: 140 HIERFNPAFLELTKILK---TEELLAIEAHRMSPYSQRANDVSVVLDLMIHDIDLLLELV 196

Query: 181 TSRVIEVYAKARNVKHPAKVEDYALILLSFENGANGIIETNRLTPHKTRTLNVVGTEGIA 240
            S V+++ A          + DY    L F +G    +  +++T  K R++       + 
Sbjct: 197 GSEVVKLSASGSRASGSGYL-DYVTATLGFSSGIVATLTASKVTHRKIRSIAAHCKNSLT 255

Query: 241 YLDYINQELTLYNE---EW--------------IYKAKINKEEPLKLEIEHFLECVKEGK 283
             D++N E+ ++ +   +W              I K   +  EPL  E+EHF+ CV+ G 
Sbjct: 256 EADFLNNEILIHRQTTADWSADYGQVLYRQDGLIEKVYTSNIEPLHAELEHFIHCVRGGD 315

Query: 284 KPLVGGEEGLHALKVA 299
           +P VGGE+ L ALK+A
Sbjct: 316 QPSVGGEQALKALKLA 331


>sp|P40332|YISS_BACSU HYPOTHETICAL 37.5 KD PROTEIN IN DEGA-NPRB INTERGENIC REGION
           >gi|7429794|pir||B69838 myo-inositol 2-dehydrogenase
           homolog yisS - Bacillus subtilis
           >gi|1934841|emb|CAB07962.1| (Z93940) unknown [Bacillus
           subtilis] >gi|2145385|emb|CAA70648.1| (Y09476) YisS
           [Bacillus subtilis] >gi|2633420|emb|CAB12924.1| (Z99109)
           alternate gene name: yuxD, yucG~similar to myo-inositol
           2-dehydrogenase [Bacillus subtilis]
           Length = 342
           
 Score =  136 bits (340), Expect = 2e-31
 Identities = 96/332 (28%), Positives = 166/332 (49%), Gaps = 21/332 (6%)

Query: 1   MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKD--YRE 58
           +R  V+G+G++GY+HA+  + +      +L+ V D    RA++VA       + +  Y  
Sbjct: 5   VRCAVLGLGRLGYYHAK--NLVTSVPGAKLVCVGDPLKGRAEQVARELGIEKWSEDPYEV 62

Query: 59  LIKEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLM 118
           L   G+DAV I  PTS H ++ +   EN   + VEKP+  S+E ++   +  K+  V+  
Sbjct: 63  LEDPGIDAVIIVTPTSTHGDMIIKAAENGKQIFVEKPLTLSLEESKAASEKVKETGVICQ 122

Query: 119 VGHVERFNPAVLKLKETIERGMLGEIV---TMTAKRVGPMVTRIS-DVGVIIDLAVHDID 174
           VG + RF+PA    K  I+ G +G+ +     T  +  P    I    G+ ID ++HD D
Sbjct: 123 VGFMRRFDPAYADAKRRIDAGEIGKPIYYKGFTRDQGAPPAEFIKHSGGIFIDCSIHDYD 182

Query: 175 VMSFLTTSRVIEVYAKARNVKHPAKVE----DYALILLSFENGANGIIETNRLTP--HKT 228
           +  +L  + +  V    R + +P   +    D AL  + F++GA G +E +R +P  H  
Sbjct: 183 IARYLLGAEITSVSGHGRILNNPFMEQYGDVDQALTYIEFDSGAAGDVEASRTSPYGHDI 242

Query: 229 RTLNVVGTEGIAYLDYI-NQELTLYNE-----EWIYKAKINKEEPLKLEIEHFLECVKEG 282
           R   V+GTEG  ++  + +Q +T+ +      + I   +    E   LE++HF ECV+ G
Sbjct: 243 RA-EVIGTEGSIFIGTLRHQHVTILSAKGSSFDIIPDFQTRFHEAYCLELQHFAECVRNG 301

Query: 283 KKPLVGGEEGLHALKVAVKALESSKKDEVVRV 314
           K P+V   +    L+V + A  S +    V++
Sbjct: 302 KTPIVTDIDATINLEVGIAATNSFRNGMPVQL 333


>pir||A75025 NADH-dependent dyhydrogenase related protein PAB1138 - Pyrococcus
           abyssi (strain Orsay) >gi|5459153|emb|CAB50639.1|
           (AJ248288) NADH-dependent DYHYDROGENASE RELATED PROTEIN
           [Pyrococcus abyssi]
           Length = 341
           
 Score =  132 bits (328), Expect = 6e-30
 Identities = 96/347 (27%), Positives = 165/347 (46%), Gaps = 46/347 (13%)

Query: 1   MRVGVVGVGKM-GYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYREL 59
           ++VG++G G +    H      L    KV  + V DI+ E A++  +    + F    E 
Sbjct: 5   LKVGIIGCGNIFNLAHKPALKSLRTIAKV--VAVMDIDEEAARKAGKELNAKVFTSLDEF 62

Query: 60  IKEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMV 119
           +++ ++ V I  PT  H E+ ++ ++    V+VEKPIA ++E A+++IK A+   + L V
Sbjct: 63  LEQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFV 122

Query: 120 GHVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTRISDV----------------- 162
           GHV RF+   +++K+ I+           ++ + PM  R  +V                 
Sbjct: 123 GHVRRFDKRWIQIKDIIK-----------SRNILPMQIRKIEVQHLPFPADYWYWDESKS 171

Query: 163 -GVIIDLAVHDIDVMSFLTTSRVIEVYAKARNVKHPAKV---EDYALILLSFENGANGII 218
            GVI+DL VH  D + +   S  IEV+A  + ++  A+V    D+ ++ + FE G  GI 
Sbjct: 172 GGVIVDLGVHVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIG 231

Query: 219 ETNRLTPHKTR------TLNVVGTEG-IAYLDYINQELTLYNEEW----IYKAKINKEEP 267
           E +   P   +       L+++G  G I Y       + +    +             + 
Sbjct: 232 EVSWSYPMPPKYGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPRFSPMLSTFPQA 291

Query: 268 LKLEIEHFLECVKEGKKPLVGGEEGLHALKVAVKALESSKKDEVVRV 314
            + E+ HF EC+K   +P+V  ++ L ALK+A KA ES KK E V+V
Sbjct: 292 FEAELRHFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKV 338


>pir||D71201 hypothetical protein PH1881 - Pyrococcus horikoshii
           >gi|3258320|dbj|BAA31003.1| (AP000007) 371aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 371
           
 Score =  130 bits (323), Expect = 2e-29
 Identities = 97/336 (28%), Positives = 159/336 (46%), Gaps = 24/336 (7%)

Query: 1   MRVGVVGVGKM-GYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYREL 59
           ++VGV+G G +    H      L    KV  + V DIN E AK+  +    + F    E 
Sbjct: 35  LKVGVIGCGNIFNLAHKPALRSLRTIAKV--VAVMDINEEAAKKAGKELNAKVFTSLDEF 92

Query: 60  IKEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMV 119
           +++ +D V +  PT  H E+ +  ++    V+VEKPIA + E A+++IK A++  + L V
Sbjct: 93  LEQDMDVVEVLTPTYTHAEIAIKALKAGKHVIVEKPIALTSEEAEKMIKEAEEQGLKLFV 152

Query: 120 GHVERFNPAVLKLKETIE-RGMLGEIVTMTAKRVGPMVT------RISDVGVIIDLAVHD 172
           GHV RF+    ++KE I+ R +L   +     +  P              GVIIDL VH 
Sbjct: 153 GHVRRFDKRWTQIKEVIKTRNILPMQIRKIEVQHLPFPADYWYWDESKSGGVIIDLGVHV 212

Query: 173 IDVMSFLTTSRVIEVYAKARNVKHPAKVE---DYALILLSFENGANGIIETNRLTPHKTR 229
            D + +   S  +EV+A  + ++  A+V    D+ ++ + FE    GI E +   P   +
Sbjct: 213 TDFLRWFFESEPVEVFAVGKAIRGEARVNKTYDHVVMFIKFEGNKTGIGEVSWSYPMTPK 272

Query: 230 ------TLNVVGTEG-IAYLDYINQELTLYNEEW----IYKAKINKEEPLKLEIEHFLEC 278
                  L+++G  G I Y       + +    +             +  + E+ HF EC
Sbjct: 273 YGVFYHHLDIIGKNGRIRYTPLDTPVVGVIKSSFEMPRFSPMLSTFPQAFEAELRHFFEC 332

Query: 279 VKEGKKPLVGGEEGLHALKVAVKALESSKKDEVVRV 314
           +K   +P+V   + L AL++A KA ES KK E V+V
Sbjct: 333 IKSNCEPVVTARDALIALQIAEKARESIKKGEPVKV 368


>pir||D72381 dehydrogenase - Thermotoga maritima (strain MSB8)
           >gi|4980919|gb|AAD35499.1|AE001720_13 (AE001720)
           dehydrogenase [Thermotoga maritima]
           Length = 334
           
 Score =  129 bits (322), Expect = 3e-29
 Identities = 91/333 (27%), Positives = 172/333 (51%), Gaps = 23/333 (6%)

Query: 1   MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKT-RAFKDYREL 59
           MR+GV+G+G++G  HA     L       L  ++D+  +R +E+ E     +A+KD  EL
Sbjct: 1   MRIGVIGLGRIGTIHAE---NLKMIDDAILYAISDVREDRLREMKEKLGVEKAYKDPHEL 57

Query: 60  IKE-GVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLM 118
           I++  VDAV +   T+ H E+ +   + +  V  EKP++ ++     +I+  KK +V+L 
Sbjct: 58  IEDPNVDAVLVCSSTNTHSELVIACAKAKKHVFCEKPLSLNLADVDRMIEETKKADVILF 117

Query: 119 VGHVERFNPAVLKLKETIERGMLGE--IVTMTAKRVGPM---VTRISDVGVIIDLAVHDI 173
            G   RF+    KLKE +E G +G+  ++ +T++   P      R+S  G+ +D+ +HD 
Sbjct: 118 TGFNRRFDRNFKKLKEAVENGTIGKPHVLRITSRDPAPPPLDYIRVSG-GIFLDMTIHDF 176

Query: 174 DVMSFLTTSRVIEVYAKARNVKH----PAKVEDYALILLSFENGANGIIETNRLTPH-KT 228
           D+  ++    V EV+A    +       A   D A+++L F++GA G+I+ +R   +   
Sbjct: 177 DMARYIMGEEVEEVFADGSVLVDEEIGKAGDVDTAVVVLRFKSGALGVIDNSRRAVYGYD 236

Query: 229 RTLNVVGTEGIAYLDYINQELTLYNEE-------WIYKAKINKEEPLKLEIEHFLECVKE 281
           + + V G++G  + D + +   +  +E       ++Y       +    E++ F++ VK 
Sbjct: 237 QRIEVFGSKGRIFADNVRETTVVLTDEQGDRGSRYLYFFLERYRDSYLEELKTFIKNVKS 296

Query: 282 GKKPLVGGEEGLHALKVAVKALESSKKDEVVRV 314
           G+ P V GE+G  AL +   A +S ++   V++
Sbjct: 297 GEPPAVSGEDGKMALLLGYAAKKSLEEKRSVKL 329


>gb|AAK43117.1| Dehydrogenase, putative [Sulfolobus solfataricus]
           Length = 355
           
 Score =  129 bits (322), Expect = 3e-29
 Identities = 97/353 (27%), Positives = 174/353 (48%), Gaps = 39/353 (11%)

Query: 1   MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELI 60
           +R G++GVG  G +   +   +  + KVE++ VAD+  ER +EV+  F  + + DY E++
Sbjct: 3   IRYGIIGVGGHGKNR-HLIPLIKLKNKVEIVAVADVKKERCEEVSSQFNIKCYLDYMEMV 61

Query: 61  -KEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMV 119
            KE ++AVSI  PT LH  + ++ +   V+VLV+KP+  ++E  +E++  A+   + LMV
Sbjct: 62  EKESLNAVSIVTPTGLHSRIAINVLNKGVNVLVDKPLGSNLEEVKEVVNTARNKGLKLMV 121

Query: 120 GHVERFNPAVLKLKETIERGMLGEIVT----MTAKRVGPMVTRISDV------GVIIDLA 169
           G+  RF+PA+   KE I  G+LGE       +  +R  P +    D       G ++D+ 
Sbjct: 122 GYWSRFSPALQYGKEIIHNGLLGEPYVAYGYLVRRRGIPGIPTFIDKTLSGGRGALLDIG 181

Query: 170 VHDID-VMSFLTTSRVI----EVYAKARNVKHPAK------------VEDYALILLSFEN 212
            + ID ++S L   + I    +VY K  NVK   K            ++DYA+ L+  E 
Sbjct: 182 CYLIDNLLSLLKFRKPISVMGKVYTKFGNVKEEVKFNWGSWDPENFSLDDYAVGLVKLEG 241

Query: 213 GANGIIE----TNRLTPHKTRTLNVV----GTEGIAYLDYINQELTLYNEEWIYKAK--I 262
             + I+E     N     +   + ++    G EG  +   ++       E ++   K  +
Sbjct: 242 DVSLILEVGWSANVSHVEEKSYVRILGDKGGIEGSGHEAIVDISFHSRTENFLTDTKPVL 301

Query: 263 NKEEPLKLEIEHFLECVKEGKKPLVGGEEGLHALKVAVKALESSKKDEVVRVS 315
            K +P    I  F++ +   ++P + GEE +    +     +SS +D+ V++S
Sbjct: 302 RKVDPYFEMINAFVDSILTDREPPITGEESVTLHSIIDGIYKSSTEDKEVKIS 354


>dbj|BAB04967.1| (AP001511) NADH-dependent dyhydrogenase [Bacillus halodurans]
           Length = 340
           
 Score =  129 bits (320), Expect = 5e-29
 Identities = 94/340 (27%), Positives = 162/340 (47%), Gaps = 29/340 (8%)

Query: 1   MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELI 60
           +RV V+G G +  H  R   E  +     ++ V D   ERAK+VA+ +   A+ D+ +L+
Sbjct: 4   LRVAVIGCGSIAQH--RHLPEYEQNPHTTIVAVCDPVEERAKKVAKLYGAIAYTDHMQLL 61

Query: 61  -KEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMV 119
            KE +D VS+  P + H  +++D ++    VL EKP+A S E  + +IKAA++  + LM+
Sbjct: 62  EKEEIDLVSVCTPNAYHAPISIDALKAGTHVLCEKPMATSAEECEAMIKAAEEAGMCLMI 121

Query: 120 GHVERFNPAVLKLKETIERGMLGEIVTM--TAKRVGPMVTRISD------------VGVI 165
           GH +RF  +  K ++ I  G +G+I +   T    GP    +              +G +
Sbjct: 122 GHNQRFVSSHEKARQLIATGDIGKIYSFRTTFGHGGPEGWSVDGENSWFFKKDQAFIGAM 181

Query: 166 IDLAVHDIDVMSFLTTSRVIEVYAKARNVKHPAKVEDYALILLSFENGANGIIETN-RLT 224
            DL VH  D++ +L    V+EV A          V+D A+ +L  E+G  G +  +    
Sbjct: 182 GDLGVHKADLLRYLLGEEVVEVGAFVTTSAKQGDVDDNAVAILKTESGIVGTLTASWSYV 241

Query: 225 PHKTRTLNVVGTEGIAYLD----------YINQELTLYNEEWIYKAKINKEEPLKLEIEH 274
             +  +  + G   I  L+          Y N E   Y    I       +   ++ I H
Sbjct: 242 AKEDNSTILYGENAILRLEDDPHYSLIVHYKNGETVKYELGQIQSNDEGGQTDSRV-IAH 300

Query: 275 FLECVKEGKKPLVGGEEGLHALKVAVKALESSKKDEVVRV 314
           F+  V EGK+P + G+EG  +L + + A+E+S+    +++
Sbjct: 301 FVNSVLEGKEPPISGKEGYASLNIILAAMEASRTGRTIKL 340


>sp|O05389|YRBE_BACSU HYPOTHETICAL 37.8 KDA PROTEIN IN CSBX-NADA INTERGENIC REGION (ORF1)
           >gi|7429795|pir||D69972 opine catabolism homolog yrbE -
           Bacillus subtilis >gi|2635242|emb|CAB14737.1| (Z99118)
           similar to opine catabolism [Bacillus subtilis]
           >gi|6977802|emb|CAB75327.1| (Y15896) hypothetical
           protein [Bacillus subtilis]
           Length = 341
           
 Score =  124 bits (309), Expect = 1e-27
 Identities = 88/320 (27%), Positives = 161/320 (49%), Gaps = 21/320 (6%)

Query: 4   GVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAF-KDYRELIKE 62
           G++G G++G  H +  S +     +++  ++DI   R K  A++ +      DYR+L+ +
Sbjct: 8   GIIGAGRIGKLHVQNISRIPH---MKIKAISDIQASRIKSWADSHQIEYITSDYRDLLHD 64

Query: 63  -GVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMVGH 121
             +DA+ I  PT++H ++  +  E +  +  EKP++ S++   E + A +K  V L VG 
Sbjct: 65  PDIDAIFICSPTAVHAQMIKEAAEAKKHIFCEKPVSFSLDETSEALAAVRKHGVTLQVGF 124

Query: 122 VERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTRISDV----GVIIDLAVHDIDVMS 177
             RF+P   K+K  +E G +G    +      P    I  V    G+ +D+++HD D+  
Sbjct: 125 NRRFDPHFKKIKTIVENGEIGTPHLLKITSRDPEPPNIDYVRTSGGLFMDMSIHDFDMAR 184

Query: 178 FLTTSRVIEVYAKARNVKHPAKVE----DYALILLSFENGANGIIETNRLTPH-KTRTLN 232
           ++  S V EVYAK   + +P+  E    D A+I L+FENGA  +I+ +R   +   + + 
Sbjct: 185 YIMGSEVTEVYAKGAALVNPSFAELGDIDTAVITLTFENGAMAVIDNSRQAVYGYDQRVE 244

Query: 233 VVGTEGIAYLDYIN-QELTLYNEEWIYKAKIN------KEEPLKLEIEHFLECVKEGKKP 285
           V GT+G A  D      + +   +++ K K +       ++  + EI  F E +   ++ 
Sbjct: 245 VFGTKGSAAADNSRPTTVEVSTADFVMKDKPHFFFLERYKDSYEEEILRFAEAIGTNQET 304

Query: 286 LVGGEEGLHALKVAVKALES 305
              G +GL A ++A  A +S
Sbjct: 305 PCTGNDGLQAGRIARAAQQS 324


>pir||B72359 lipopolysaccharide biosynthesis protein BplA - Thermotoga maritima
           (strain MSB8) >gi|4981103|gb|AAD35670.1|AE001733_7
           (AE001733) lipopolysaccharide biosynthesis protein BplA
           [Thermotoga maritima]
           Length = 360
           
 Score =  123 bits (307), Expect = 2e-27
 Identities = 92/330 (27%), Positives = 160/330 (47%), Gaps = 31/330 (9%)

Query: 1   MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFK------ 54
           +R+ +VG G++G     + + +  +   E + V D+  ERA   AE F+    +      
Sbjct: 3   LRIALVGCGRIG-QKKHVPALIETQDLFETVAVCDLVEERANRAAEHFEKSGLRRPETMT 61

Query: 55  DYRELIK-EGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKM 113
           +YREL+K E VD +SIA  +  H ++TM+ +E    VLVEKP+A S +   E+++ +K+ 
Sbjct: 62  NYRELLKREDVDVISIATESGKHYQITMEALEAGKHVLVEKPMALSTKHMNEMVELSKQK 121

Query: 114 NVVLMVGHVERFNPAVLKLKETIERGMLGEIVTMTA-----------KRVGPMVTRISDV 162
           N+ L V    RFNP V ++++ ++ G  G+I   +            K+     T   D 
Sbjct: 122 NLKLGVFFQNRFNPPVQEVRKKLDSGAFGKIFYASVAVRWNRNEDYYKQASWRGTWEMDG 181

Query: 163 GVIIDLAVHDIDVMSFLTTSRVIEVYAKARNVKHP-AKVEDYALILLSFENGANGIIE-T 220
           GV+++ + H ID++ +     + E+Y    N  HP  + ED    ++ F+ G  G+IE T
Sbjct: 182 GVLMNQSTHAIDLLQWFLGGEIEEIYGHIANTNHPYIEAEDEGFAIVKFKGGKTGLIEAT 241

Query: 221 NRLTPHK-TRTLNVVGTEGIAYLD--YINQELTLYNEEWIYKAKINKEEP-------LKL 270
           + + P     TL + G +G   +    +N+ LT   E       +N  +P        K 
Sbjct: 242 SNVFPRNLEETLAIFGEKGTVVIGGIAVNRILTWRFEGEEGHPFMNLPDPDTVYGDSHKY 301

Query: 271 EIEHFLECVKEGKKPLVGGEEGLHALKVAV 300
               F E V   +KP + GE+G  A+++ +
Sbjct: 302 VYRDFYEAVTNDRKPYISGEDGKKAVEIVL 331


>pir||B75025 NADH-dependent dyhydrogenase related protein PAB1139 - Pyrococcus
           abyssi (strain Orsay) >gi|5459154|emb|CAB50640.1|
           (AJ248288) NADH-dependent DYHYDROGENASE RELATED PROTEIN
           [Pyrococcus abyssi]
           Length = 335
           
 Score =  122 bits (302), Expect = 7e-27
 Identities = 98/333 (29%), Positives = 161/333 (47%), Gaps = 29/333 (8%)

Query: 7   GVGKMGYHHARIYSELAKEGK-VELIGVAD--INFERAKEVAETFKTRAFKDYRELIK-E 62
           GV    + HA  Y+   +  +  +L+ ++    N   AK  A+ +  + ++DY +L++ E
Sbjct: 5   GVISYAHPHALRYAATIRANRRAKLVAISGDGANSGLAKIEAKKYGAKFYQDYEKLLRDE 64

Query: 63  GVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMVGHV 122
            V+AV IA+ T  H+EV +   E    +L+EKPIA ++E  +EI+KAA+K  V LMV   
Sbjct: 65  SVEAVYIAIETYRHKEVAIRAAEEGKDILLEKPIALTLEDGKEIVKAARKAGVKLMVPFN 124

Query: 123 ERFNPAVLKLKETIERGMLGE---IVTMTAKRVGPMVTRISDV-----------GVIIDL 168
            RF   + K KE IE+G +G+   I T++     PM     D            G  +D 
Sbjct: 125 PRFTQPLQKAKEMIEKGEIGKLEYIYTISEYVKPPMFLEGIDTSWFFDIKKSGGGGFMDT 184

Query: 169 AVHDIDVMSFLTTSRVIEVYAKARNVKHPAKVEDYALILLSFENGANGIIETNRLTPH-- 226
           A H ID + +LT S  I VYA         +V+D    L+ F+NG   ++      P   
Sbjct: 185 APHGIDSLFWLTESEPIRVYADIGPKIWGFQVDDIGTALIEFKNGVIAVLTAGWANPKGY 244

Query: 227 ---KTRTLNVVGTEGIAYLDYINQELTLYNE--EWIYKAKINKEEPLKLEIEHFLECVKE 281
                    +VG +G   +     + T+Y +  E I+  + + E      +  F++ +++
Sbjct: 245 PYGLEIKYYIVGDDGFLDIRSAYPDFTVYQDKTEKIFWERADVEG----IVNAFIDAIQQ 300

Query: 282 GKKPLVGGEEGLHALKVAVKALESSKKDEVVRV 314
            K+P + GE+ L  L V + A ESSK  + V+V
Sbjct: 301 DKEPPITGEDALKNLAVVLAAYESSKTGKAVKV 333


>pir||E71201 probable glucose-fructose oxidoreductase - Pyrococcus horikoshii
           >gi|3258321|dbj|BAA31004.1| (AP000007) 335aa long
           hypothetical glucose-fructose oxidoreductase [Pyrococcus
           horikoshii]
           Length = 335
           
 Score =  121 bits (301), Expect = 9e-27
 Identities = 94/326 (28%), Positives = 160/326 (48%), Gaps = 28/326 (8%)

Query: 14  HHARIYSELAKEGKVELIGVAD--INFERAKEVAETFKTRAFKDYRELIKE-GVDAVSIA 70
           H  R  S +    + +L+ ++    N   AK  A+ +  + +++Y +L+K+  V+AV IA
Sbjct: 13  HALRYASTIRASRRAKLVAISGDGANSALAKVEAKKYGAKFYQNYEQLLKDKSVEAVYIA 72

Query: 71  VPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMVGHVERFNPAVL 130
           + T  H+EV +   E    +L+EKPIA ++E  +EI+KAA+K  V LMV    RF   + 
Sbjct: 73  IETYRHKEVAIRAAEEGKDILLEKPIALTLEDGKEIVKAARKAGVKLMVPFNPRFTQPLQ 132

Query: 131 KLKETIERGMLGE---IVTMTAKRVGPMV-----------TRISDVGVIIDLAVHDIDVM 176
           K KE IE G +G+   I T++     PM             R S  G  +D A H ID +
Sbjct: 133 KAKEMIESGEIGKLEYIYTISEYVKPPMFLEGIDTSWFFDIRKSGGGGFMDTAPHGIDSL 192

Query: 177 SFLTTSRVIEVYAKARNVKHPAKVEDYALILLSFENGANGIIETNRLTPH-----KTRTL 231
            +LT S  ++VYA   +     +V+D    L+ F+N    ++      P           
Sbjct: 193 FWLTESEPVKVYADIGSKIWGFEVDDIGTALIEFKNNVIALLTAGWANPKGYPYGLEMKY 252

Query: 232 NVVGTEGIAYLDYINQELTLYNE--EWIYKAKINKEEPLKLEIEHFLECVKEGKKPLVGG 289
            +VG +G   +     + T+Y E  E I+  + + E      I  F++ +++ ++P + G
Sbjct: 253 YIVGDDGFLDIRTAYPDFTVYQEKTEKIFWERADVEG----IINAFIDAIQQDREPPITG 308

Query: 290 EEGLHALKVAVKALESSKKDEVVRVS 315
           E+ L  L + + A ESSK  +VV+++
Sbjct: 309 EDALKNLALVLAAYESSKTGKVVKIN 334


>pir||A81396 hypothetical protein Cj0504c [imported] - Campylobacter jejuni
           (strain NCTC 11168) >gi|6967973|emb|CAB75141.1|
           (AL139075) hypothetical protein Cj0504c [Campylobacter
           jejuni]
           Length = 288
           
 Score =  115 bits (286), Expect = 5e-25
 Identities = 81/279 (29%), Positives = 145/279 (51%), Gaps = 15/279 (5%)

Query: 1   MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELI 60
           M++G++G+GKMG +H    +EL+K    +L  + D+       +   F    + D  + +
Sbjct: 1   MKIGIIGLGKMGQNHL---NELSKNSHFKLNALFDLCKNPNLNI---FDDIFYDDLDKFL 54

Query: 61  KEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMVG 120
            +  D + IA PT+ H  +     +    VL+EKP+A +++   EI   AK+ ++ + VG
Sbjct: 55  NQNNDIIIIATPTNSHLTIAKKVFKQCKCVLIEKPLALNLKEIDEISNLAKEYSIKVGVG 114

Query: 121 HVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTRISDVGVIIDLAVHDIDVMSFLT 180
             ERFNPAVL LK+ +E     EI+++  +R  P   RISDVG++ DLAVHD+D++ FL+
Sbjct: 115 FCERFNPAVLALKKELEN---EEIISINIQRFSPYPQRISDVGILQDLAVHDLDLLCFLS 171

Query: 181 TSRVIEVYAKARNVKHPAKVEDYALILLSFENGANGIIETNRLTPHKTRTLNVVGTEGIA 240
              + +     +  +   + E  ++IL   E     I ++   T  K R ++++ T+   
Sbjct: 172 KQEITKTNLLKKYTQDQTR-ESESIILCGLEKCIASIHQSWNST-QKLRKIHLI-TKNHF 228

Query: 241 YLDYINQELTLYNEEWIYKAKINKEEPLKLEIEHFLECV 279
           Y   +N    L +  +I   ++ ++ PL  E E  L+ +
Sbjct: 229 YEANLNDFSLLKDGNFI---ELTQQSPLFSEHEALLKLI 264


>gb|AAK43113.1| Dehydrogenase, putative [Sulfolobus solfataricus]
           Length = 363
           
 Score =  108 bits (268), Expect = 7e-23
 Identities = 89/349 (25%), Positives = 172/349 (48%), Gaps = 38/349 (10%)

Query: 1   MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELI 60
           M++G+VG+G  G+        L   G +++   ADI+ +R K++++    + + DY+E++
Sbjct: 4   MKLGIVGLG--GWVTGAHIPALTDLG-IKVDYCADIDEKRVKDLSQKTGCKGYLDYKEML 60

Query: 61  K-EGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMV 119
           + E  D V +AVP SLH  + +D I N+ +V VEKP+A S + A  +++A++K N +L+V
Sbjct: 61  RNENPDLVLVAVPHSLHAIIALDAINNDANVYVEKPMATSFQEALTLVEASRKRNKILVV 120

Query: 120 GHVERFNPAVLKLKETIERGMLGEIVTMTAKRV-------GPMVTR--ISDVGVIIDLAV 170
           GH  RFNPA+L  K+ I  G +G+I  M    +        P   +  ++  G + D+  
Sbjct: 121 GHENRFNPAMLIAKKLIRGGEVGKIYHMRGFYIRQRGIPTSPTFIKKDLAKGGAVFDIGT 180

Query: 171 HDIDVMSFLT--------TSRVIEVYA--KARNVKHPA--------KVEDYALILLSFEN 212
           H ID++ FL+        T +    ++  K +   +P+        +VED+    L   +
Sbjct: 181 HIIDLLLFLSDFPTPKSVTGKTYNAFSEDKTKFSAYPSPNLPNFKVEVEDFGSAFLKLGD 240

Query: 213 GANGIIETNRLTPHKTRTLNVV--GTEGIAYLD--YINQELTLYNEEWIYKAKINKEEPL 268
             +  +E +  +  K   + VV  G  G  ++D   +N    + +E +I      ++  +
Sbjct: 241 EISAYVEVSWASYIKENKMEVVILGDNGGIHIDNGVLNFMRNIEDELFISSPLTQQKGSV 300

Query: 269 KLEI-EHFLECVKEG--KKPLVGGEEGLHALKVAVKALESSKKDEVVRV 314
             E+    +E + +G  + PL   E+G   + +     +S+ +   V++
Sbjct: 301 YREVWRTVMESISKGFPEYPLCSAEQGAIGVAILESIYKSALEGREVKI 349


>dbj|BAB05884.1| (AP001514) unknown conserved protein [Bacillus halodurans]
           Length = 348
           
 Score =  107 bits (265), Expect = 2e-22
 Identities = 93/346 (26%), Positives = 166/346 (47%), Gaps = 37/346 (10%)

Query: 1   MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTR-AFKDYREL 59
           +RVG++G G +      I S L+ + +VEL+ + D+  + A+  AE F     + D   +
Sbjct: 6   LRVGIIGAGGIA-RTVHIPSYLSLKDQVELVAITDVQPKHAQAAAEQFSIPYVYNDASRM 64

Query: 60  IKE-GVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLM 118
           ++E  +DAVSI  P + HRE+T++ +     VL EKP A ++E A+++  AAK+   +L 
Sbjct: 65  MQEVELDAVSICTPNAFHRELTIEALHAGCHVLCEKPPAITVEDAKQMEAAAKETGNLLT 124

Query: 119 VGHVERFNPAVLKLKETIERGMLGEIVTMTAKRV--------GPMVTR-ISDVGVIIDLA 169
            G   R +P V  LK  ++ G LGEI  +  + +        G    + +   G +ID+ 
Sbjct: 125 YGFHYRHSPEVETLKRFVDEGELGEIYHVRVQAIRRRGIPGWGVFTNKELQGGGPLIDIG 184

Query: 170 VHDID----VMSFLTTSRVIEVYAKARNVKHPA-----------KVEDYALILLSFENGA 214
           VH +D    VM F   + ++    +    K               +ED A+ +++F+NGA
Sbjct: 185 VHMLDTALYVMGFPEPATILGQTHRKIGTKEGVGLLGEWNWQQFSIEDMAVGMITFKNGA 244

Query: 215 NGIIETNRLTPHKTR---TLNVVGTEGIAYL----DYINQELTLYNEEWIYKAKINKEEP 267
           +  IET      K +    ++  G +G A L     Y  +  TL +   +Y    N  E 
Sbjct: 245 SLTIETAFAANVKEQDHMNVSFFGDKGGADLFPLSIYQEKHRTLLDITPVYLPTYNHHE- 303

Query: 268 LKLEIEHFLECVKEGKKPLVGGEEGLHALKVAVKALESSKKDEVVR 313
              EI+HF++C    ++PL   E+G+   ++     +S++  + ++
Sbjct: 304 --REIKHFVDCCFRLEQPLATPEQGIVIQRLIQGLYQSAESGKAIQ 347


>pir||A83617 probable oxidoreductase PA0237 [imported] - Pseudomonas aeruginosa
           (strain PAO1) >gi|9946075|gb|AAG03626.1|AE004461_9
           (AE004461) probable oxidoreductase [Pseudomonas
           aeruginosa]
           Length = 347
           
 Score =  102 bits (253), Expect = 4e-21
 Identities = 86/340 (25%), Positives = 149/340 (43%), Gaps = 40/340 (11%)

Query: 1   MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELI 60
           +R+ ++G G MG  H   Y  L +     L  VAD    + +  A       F D+R L+
Sbjct: 5   LRIALIGAGNMGRQH---YHRLQRIAGARLCAVAD---PQGQAFAADTGVPWFGDHRRLL 58

Query: 61  KEG-VDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMV 119
           +E    A  +A P +LH    +D +   V +L+EKP+   ++   E++  A++  V L+V
Sbjct: 59  EEARPQAAIVANPNNLHVATALDCLAAGVPLLLEKPVGVQLDEVSELVAVARRSGVPLLV 118

Query: 120 GHVERFNPAVLKLKETIERGMLGEIVTMTA----KRVGPMV----TRISDVGVIIDLAVH 171
           GH  R NP V++ ++ I  G LG ++++TA    K+          R    G+++   +H
Sbjct: 119 GHHRRHNPLVVRARQLIAEGALGRLLSVTALWQLKKPDSYFEVAWRREPGAGMLLTNLIH 178

Query: 172 DIDVMSFLTTSRVIEVYAKARNVKHPAKVEDYALILLSFENGANGIIE------------ 219
           D+D++  L    V EV A A N       ED   +LL F NGA G +             
Sbjct: 179 DLDLLRHL-CGEVREVQALAGNAIRGLPNEDNIALLLRFANGALGSLTGCDAAAAPWSWE 237

Query: 220 ----TNRLTPHKTR--TLNVVGTEGIAYLDYINQ-ELTLYNEEWIYKAKINKE-----EP 267
                N + P +       + GTEG   L  + +       + W      ++E     +P
Sbjct: 238 LAAGENPVYPRQAEQPCYLLAGTEGALSLPQLRRWRYAEARQGWHDPLAASEEAVATGDP 297

Query: 268 LKLEIEHFLECVKEGKKPLVGGEEGLHALKVAVKALESSK 307
           L+ ++EHF+   +  + PL+   +    L +     E+++
Sbjct: 298 LQRQLEHFVRVARGEEAPLMDATDAARTLALVEAVREAAR 337


>dbj|BAB05939.1| (AP001514) dehydrogenase [Bacillus halodurans]
           Length = 345
           
 Score =  102 bits (252), Expect = 5e-21
 Identities = 84/340 (24%), Positives = 153/340 (44%), Gaps = 30/340 (8%)

Query: 1   MRVGVVGVGKMGYHHARIYSELA-KEGKVELIGVADINFERAKEVAETFKTR-AFKDYRE 58
           ++VG+VG+G++G  H      LA +  + EL  V  +     K+  E +     +  Y E
Sbjct: 4   VKVGLVGLGRLGQQHG---DNLAFRIPRCELTAVCSVVEAEVKQARERWGVPYGYTSYEE 60

Query: 59  LI-KEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKK-MNVV 116
           ++  E +DA+ IA P+  H E     +E    V  EKP+   +   +E+  A  +  + V
Sbjct: 61  MLANEELDAIFIASPSGFHCEQIKKGLEKGFHVFCEKPLGLHLAEVREVENAVNRHKDQV 120

Query: 117 LMVGHVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPM--------VTRISDVG-VIID 167
            M+G + R++P+    KE I RG +GE V +    + P           + +D G + +D
Sbjct: 121 FMLGFMRRYDPSYQAAKEKINRGEIGEPVLIRCYGLDPASQIDGFLAFAKANDSGGLFLD 180

Query: 168 LAVHDIDVMSFLTTSRVIEVYAKARNVKHPAKVE----DYALILLSFENGANGIIETNRL 223
           +++HD D+  +   +   EV+A   +   P   E    +    ++ F+N A G+    R 
Sbjct: 181 MSIHDFDLARWYLGAEASEVWAIGGSYSRPEFAELGDAETGAAMVRFDNQAIGLFVAGRN 240

Query: 224 TPH----KTRTLNVVGTEGIAYLDYINQELTLYNEEWIYKAKINK-----EEPLKLEIEH 274
             H    +T  +   GT  I  +   NQ + + NE  +    +       E+  + E E 
Sbjct: 241 CAHGYHIETEIIGTKGTIRIGSIPERNQAVVM-NEHGVIHECVQGFIERFEQAYRAEAEE 299

Query: 275 FLECVKEGKKPLVGGEEGLHALKVAVKALESSKKDEVVRV 314
           F+ C+ EG+KP V  ++G+ + K+     +S     ++ V
Sbjct: 300 FIRCILEGRKPDVTVKDGVESTKLGYACKQSFTTKTLINV 339


>gb|AAK43149.1| Dehydrogenase, putative [Sulfolobus solfataricus]
           Length = 371
           
 Score = 97.5 bits (239), Expect = 2e-19
 Identities = 95/345 (27%), Positives = 163/345 (46%), Gaps = 36/345 (10%)

Query: 3   VGVVGVGKMGYHHARIYSELAKEGK-VELIGVADINFERAKEVAETFKTRAFKDYRELIK 61
           V VVG+G +G  H +   +L KE + V+L+ V D     A+++   + T  +    E+++
Sbjct: 22  VAVVGLGSIGKTHVKALKDLEKETEFVKLVAVVDQIKAIAEKIGSEYGTPYYTTIDEVLR 81

Query: 62  EG-VDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMVG 120
              VD +SIA P+ LH    +  IE    V+VEKP+A ++  A+E++  A++  V L V 
Sbjct: 82  NSEVDVISIATPSYLHAPQAILAIEYGKHVIVEKPMATTLAGAREMVSRAERNEVKLGVI 141

Query: 121 HVERFNPAVLKLKETI----------------ERGMLGEIVTMTAKRVGPMVTRISDVGV 164
             ER+ P + +LK  I                 R M G        R    +      GV
Sbjct: 142 FQERYAPDIRRLKNDILKELGRIYLIESELKWYRDMKGYYKRDEIARSWRGMWNTEGGGV 201

Query: 165 IIDLAVHDIDVMSFLTTSRVIEVYAKARNVKHPA-KVEDYALILLSFENGANGIIE---T 220
           + +  +H ID+M +L    V EV     N+ H   +VED A+ ++ ++NGA G I    +
Sbjct: 202 MTNQGIHTIDLMIWL-NGEVEEVSGFVDNLTHDGIEVEDTAVAIMRYKNGALGTISQTVS 260

Query: 221 NRLTPHKTRTLNVVGTEGIAYLDYINQEL-TLYNEEWIYKAKINKE-------EPLKLE- 271
            + T ++ R + V G+ G  +++  +  L T+  E  I ++K + E       +P  L  
Sbjct: 261 MKPTTYQYRKIRVNGSNG--FVEITDGSLSTVAIEGKIEESKSSVEYKKETIAQPGNLHK 318

Query: 272 --IEHFLECVKEGKKPLVGGEEGLHALKVAVKALESSKKDEVVRV 314
             +  FL  + E     + G+EG+ +L+V      SS   +VV++
Sbjct: 319 ELLRDFLRALSEDNDFPINGKEGMKSLEVIKAVYLSSVNRQVVKL 363


>gb|AAC31183.1| (AF076240) putative NADH-inositol dehydrogenase MocA [Rhizobium
           leguminosarum bv. viciae]
           Length = 306
           
 Score = 96.0 bits (235), Expect = 5e-19
 Identities = 82/315 (26%), Positives = 132/315 (41%), Gaps = 29/315 (9%)

Query: 2   RVGVVGVGKMGYHHARIYSE---LAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRE 58
           R+G++G G+MG  H R  SE   +     VE +    +  ER+         + +K   E
Sbjct: 5   RLGLIGAGRMGQVHLRAASESLLVEVTAVVEPVAATRLALERSG-------IKTYKTADE 57

Query: 59  LIKEG-VDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVL 117
           +I  G +D V IA P+  H E   +     + +L EKP   + E A++  +AA++  V L
Sbjct: 58  MIDAGEIDGVLIATPSKTHVENITNIAARGLPILCEKPCGVTAEEARKAAEAAEQFKVHL 117

Query: 118 MVGHVERFNPAVLKLKETIERGMLGE---IVTMTAKRVGPMVT-RISDVGVIIDLAVHDI 173
            +G+  RF P + KL++ I  G+LGE   I         P  + R +  G +ID+ VH+ 
Sbjct: 118 QIGYWRRFVPELEKLRQNIRSGLLGEPYLISCFQWDETPPAASFRATGGGALIDMGVHEF 177

Query: 174 DVMSFLTTSRVIEVYAKARNVKHPAKVE---DYALILLSFENGANGIIET-NRLTPHKTR 229
           D M +LT          A       KVE   D   +L     G  G++    R  P    
Sbjct: 178 DQMRWLTGQEPSNFRVAASKTTFAGKVEGDPDAVQLLCDLSGGGVGLVSLGRRFPPGDAC 237

Query: 230 TLNVVGTEGIAYLDYINQELTLYNEEWIYKAKINKEEPLKLEIEHFLECVKEGKKPLVGG 289
              V GT G   + +           W    +      L+ ++E F++  + G       
Sbjct: 238 WAQVFGTSGFEEVRFF----------WPPNGEAVFLNALRSQLEDFVQAARGGASQGATA 287

Query: 290 EEGLHALKVAVKALE 304
           ++ + AL +A  A E
Sbjct: 288 QDAVTALAIAEAATE 302


>emb|CAB88961.1| (AL353864) putative oxidoreductase. [Streptomyces coelicolor A3(2)]
           Length = 358
           
 Score = 94.4 bits (231), Expect = 1e-18
 Identities = 66/241 (27%), Positives = 112/241 (46%), Gaps = 14/241 (5%)

Query: 1   MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELI 60
           MR+G++G+G++G  HA   + L   G +    VAD   + AK  AE F          + 
Sbjct: 25  MRIGILGLGRIGAFHAETLAGLDSVGSLV---VADPFADAAKAAAERFGAEVADSPEAVF 81

Query: 61  KEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMVG 120
             GVD V IA  T  H ++ +  +E  V V  EKP+A ++    E++KA    +V + +G
Sbjct: 82  AAGVDGVVIAAATDAHPDLILAAVEAGVPVFCEKPVARTMAEGVEVLKALAGRDVPVQIG 141

Query: 121 HVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTRISDV----GVIIDLAVHDIDVM 176
           +  RF+      +  +  G LG + T+ +  + P     + V    G+  D +VHD D +
Sbjct: 142 YQRRFDTGFAAARAAVRSGELGPLHTVRSTTLDPAPPPAAYVAASGGIFRDCSVHDFDSI 201

Query: 177 SFLTTSRVIEVYA----KARNVKHPAKVEDYALILLSFENGANGIIETNRLTPHKTRTLN 232
            ++T   V EVYA    +  +    A   D    +L+ ++G   ++  +R   H  R  +
Sbjct: 202 RWVTGREVGEVYAVGGNRGADYIREAGDADTTGAVLTLDDGTVAVVSNSR---HNARGYD 258

Query: 233 V 233
           V
Sbjct: 259 V 259


>sp|P49307|MOCA_RHIME RHIZOPINE CATABOLISM PROTEIN MOCA >gi|2120810|pir||S51572 mocA
           protein - Rhizobium meliloti >gi|468762|emb|CAA55269.1|
           (X78503) mocA [Sinorhizobium meliloti]
           Length = 317
           
 Score = 93.6 bits (229), Expect = 3e-18
 Identities = 81/318 (25%), Positives = 135/318 (41%), Gaps = 25/318 (7%)

Query: 2   RVGVVGVGKMGYHHARIYSELAKEGKVELIGVAD-INFERAKEVAETFKTRAFKDYRELI 60
           R+G+VG G+MG  H R  +E      VE+  VAD I   R        KT  ++   ++I
Sbjct: 5   RLGLVGAGRMGQVHVRAAAE---SSLVEIAAVADPIAASRLNLAGNGIKT--YETAGDMI 59

Query: 61  KEG-VDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMV 119
           + G VD V IA P++ H +   D     + +L EKP   + E A++    A++  V L +
Sbjct: 60  EAGEVDGVLIATPSNTHVDTVADIAARGLPILCEKPCGVTAEEARKAADVAERYKVHLQI 119

Query: 120 GHVERFNPAVLKLKETIERGMLGEIVTMTAKR--VGPMVT--RISDVGVIIDLAVHDIDV 175
           G+  RF P + +L++ I  G+LG +  ++  +    P     R +  G  ID+ VH+ D 
Sbjct: 120 GYWRRFVPELKQLRDDIRAGLLGNLYLVSCFQWDEAPPANSFRATGGGAFIDMGVHEFDQ 179

Query: 176 MSFLTTSRVIEVYAKARNVKHPAKVE---DYALILLSFENGANGIIET-NRLTPHKTRTL 231
           M +LT                   V+   D   +L    +G++G++    R  P      
Sbjct: 180 MRWLTGQEPTNFRVATSKTTFAGAVKGDPDAVQLLCDLSDGSSGLVSLGRRFPPGDACWT 239

Query: 232 NVVGTEGIAYLDYINQELTLYNEEWIYKAKINKEEPLKLEIEHFLECVKEGKKPLVGGEE 291
            V GT G A   +           W    +      L+ ++E F++  + G        +
Sbjct: 240 QVFGTSGFAEARFF----------WPPDGEAVFLNALQAQLEDFVQAARGGAPRGATASD 289

Query: 292 GLHALKVAVKALESSKKD 309
            + AL +A  A E   +D
Sbjct: 290 AVAALTIAEAATELLSRD 307


>pir||B75475 glucose-fructose oxidoreductase - Deinococcus radiodurans  (strain
           R1) >gi|6458511|gb|AAF10376.1|AE001934_7 (AE001934)
           glucose-fructose oxidoreductase [Deinococcus
           radiodurans]
           Length = 398
           
 Score = 93.2 bits (228), Expect = 3e-18
 Identities = 81/338 (23%), Positives = 158/338 (45%), Gaps = 30/338 (8%)

Query: 2   RVG--VVGVGKMGYHHARIYSELAKEGKVELIGVADIN----FERAKEVAETFKTRAFKD 55
           RVG  +VG+GK+        +  ++   +  +  ++ +    F RA ++       ++ D
Sbjct: 44  RVGFAIVGIGKLSAEELIPAARTSQHAYIAALVTSEEDKGEAFARAFDLTPD-DVYSYDD 102

Query: 56  YRELI-KEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMN 114
           + +L  ++ V+AV I +P SLHRE      +    VL EKP++ + + AQ ++ A +  N
Sbjct: 103 FEKLAGRDDVEAVYIVLPNSLHREYVERAAKMGKHVLCEKPLSVNEQDAQAMVDACRAAN 162

Query: 115 VVLMVGHVERFNPAVLKLKETIERGMLGEIVTMTAKRV----GPMVTR----ISDVGVII 166
           V+LM  +  ++ P     ++ ++ G LG++  + +  V     P V R    ++  G + 
Sbjct: 163 VLLMTAYRCQYTPEHWAARDAVQGGKLGKVKLLDSIHVQSEDDPSVWRLKLDLAGGGPLP 222

Query: 167 DLAVHDIDVMSFLTTSRVIEVYAKARNVKHP---AKVEDYALILLSFENGANGIIETNRL 223
           D+ ++ ++++ F+       V+A     +      +VE+    +L F  G    +  N L
Sbjct: 223 DVGLYSVNIIRFVLGQEPEWVFAALHQPEGDPRFGEVEESVSAMLGFPGG----VIANVL 278

Query: 224 TPH---KTRTLNVVGTEGIAYLD----YINQELTLYNEEWIYKAKINKEEPLKLEIEHFL 276
           T +   KT TL V+G EG   +D    Y    L +  ++  +     + +    E +HF 
Sbjct: 279 TSYGALKTTTLRVMGEEGSLLMDPAFPYDGLGLEITTDDGTFSPSFPEYDQFSREFDHFA 338

Query: 277 ECVKEGKKPLVGGEEGLHALKVAVKALESSKKDEVVRV 314
           +CV+ G+ P   GEEG+   +V     ES++  + V +
Sbjct: 339 QCVRGGQTPWTPGEEGVADHRVMDAIYESARTGKRVEL 376


>dbj|BAB04429.1| (AP001509) unknown conserved protein [Bacillus halodurans]
           Length = 388
           
 Score = 92.1 bits (225), Expect = 8e-18
 Identities = 96/383 (25%), Positives = 164/383 (42%), Gaps = 68/383 (17%)

Query: 1   MRVGVVGVGKMGYHHARIYSELAK----EGKVELIGVADINFERAKEVAETFKTRAFK-D 55
           ++VG++G   MG  H+  Y +L        + E+  +   N E   + A  +    +  +
Sbjct: 4   IKVGMIGYKFMGKAHSHAYRDLPMFFPDHLRPEMKVICGRNPEGVAQAASQYGWEEYTTN 63

Query: 56  YRELIK-EGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMN 114
           +++LI+ + +D + I  P+ +H+E+T+   +    +  EKP+A +++ ++ +++A +   
Sbjct: 64  WKDLIRRDDIDLIDINAPSDVHKEITLAAAQAGKHIFCEKPLALTLQDSRHMLEAVEAAG 123

Query: 115 VVLMVGHVERFNPAVLKLKETIERGMLGEIVTMTAKRVG--------PMVTR----ISDV 162
           V  MVG   RF PAVL  K+ I  G LG+I    A  +         P+V R    I+  
Sbjct: 124 VKHMVGFNYRFTPAVLLAKKLIAEGRLGDIYHFRAWFLQDWIVAPDFPLVWRLQKDIAGS 183

Query: 163 GVIIDLAVHDIDVMSFL--TTSRVI---EVYAKARNV------------------KHPAK 199
           G   DL  H ID+  FL    + VI   E + K R +                  K P  
Sbjct: 184 GAHGDLGAHLIDMAHFLIGDITEVIGMNETFIKERPLPTEMTGLSGRGSNDHTVPKGPVT 243

Query: 200 VEDYALILLSFENGANGIIETNRL-TPHK-TRTLNVVGTEGIAYLDYIN-QELTLY---- 252
           V+D  L +  F NGA G  E  R  T H+ T +  + G++G    D+    EL +Y    
Sbjct: 244 VDDATLFMARFANGALGSFEATRFATGHRSTNSFEINGSKGSVIFDFERLNELQVYFTDD 303

Query: 253 --------------------NEEWIYKAKINKEEPLKLEIEHFLECVKEGKKPLVGGEEG 292
                               +  W     I  E     EI   +E ++EG++P+   ++G
Sbjct: 304 QDDVQGFRRVLATDGAHAYSDRWWPAGHTIGYEHTFIHEIAELMESLQEGRQPVPNFKDG 363

Query: 293 LHALKVAVKALESSKKDEVVRVS 315
           +   +V      S  K E ++VS
Sbjct: 364 VKCQQVLEAVDLSIAKREWIQVS 386


>gb|AAC23913.1| (AF039207) NADH-dependent dehydrogenase homolog [Listeria
           monocytogenes]
           Length = 358
           
 Score = 91.7 bits (224), Expect = 1e-17
 Identities = 90/360 (25%), Positives = 157/360 (43%), Gaps = 55/360 (15%)

Query: 1   MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETF---KTRAFKDYR 57
           ++VG++G G  G  + +    L K  K E++   DI  E+A+  A+ F       + +Y 
Sbjct: 3   LKVGIIGCG--GIANGKHMPSLLKAEKAEMVAFCDIVLEKAEAAAKEFGGENASVYTNYV 60

Query: 58  ELIKE-GVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVV 116
           EL+++  +D + +  P   H E+++  +E    V+ EKP+A++   A+ +I+AA++    
Sbjct: 61  ELLQDKSIDVIHVCTPNISHAEISIAAMEAGKHVMCEKPMAKTTAEAKSMIEAAERTGKK 120

Query: 117 LMVGHVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTRISDV---------GVIID 167
           L +G+  RF      L +  E G LG+I    AK +         V         G +ID
Sbjct: 121 LTIGYQNRFRKDSDYLHQVCENGELGDIYYAKAKAIRRRAVPTWGVFLDEEAQGGGPLID 180

Query: 168 LAVHDIDVMSFL--------TTSRVIEVYAKARNVKH------PAK--VEDYALILLSFE 211
           +  H +D+  ++                 AK  N  +      P K  VED A   ++ E
Sbjct: 181 IGTHALDLTLWMMDNYKPKYVVGNSYHKLAKKENAANAWGSWDPNKFTVEDSAFGFITME 240

Query: 212 NGANGIIET----NRLTPHKTRTLNVVGTEGIAYLD---YINQELTLYNEEWIYKAKINK 264
           NGA  ++E     N L   + RT ++ GTEG A ++    IN E        +Y+ KI  
Sbjct: 241 NGATIVLEASWALNTLDVGEART-SLSGTEGGADMEDGLRINGEA----HSQMYEKKIQL 295

Query: 265 E------------EPLKLEIEHFLECVKEGKKPLVGGEEGLHALKVAVKALESSKKDEVV 312
           E            +P  +E   +L  +++   P+V   + +   ++     ESSK  + V
Sbjct: 296 EAGGVDFYDGTGDDPALIEAGQWLGAIEKNTDPVVKPGQAIVVTQILEAIYESSKTGQPV 355


>emb|CAB60174.1| (AL132824) putative dehydrogenase [Streptomyces coelicolor]
           Length = 337
           
 Score = 90.9 bits (222), Expect = 2e-17
 Identities = 66/231 (28%), Positives = 103/231 (44%), Gaps = 11/231 (4%)

Query: 1   MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELI 60
           MR+GV+G G++G  HA   S     G + L    D +  RA+E+A      A     E+ 
Sbjct: 1   MRIGVIGTGRIGTVHANTLSRHRDVGSLIL---TDADIARAQELAHRLGETAAPGVDEIF 57

Query: 61  KEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMVG 120
           + GVDAV I   T  H E+      + + V  EKPIA  +    + I   +    VL +G
Sbjct: 58  QWGVDAVVITTATPAHAELIGRAARSGLPVFCEKPIALDLPGTLQAIAEVEAAGTVLQMG 117

Query: 121 HVERFNPAVLKLKETIERGMLGEIVT---MTAKRVGPMVTRISDVGVII-DLAVHDIDVM 176
              RF+      +E +  G LG + T   +T+ +  P    +   G +  D  +HD DV+
Sbjct: 118 FQRRFDTGYTGAREAVRSGRLGRLHTVRAVTSDQTPPPADYLPQSGGLYRDTLIHDFDVL 177

Query: 177 SFLTTSRVIEVYAKARNVKHP----AKVEDYALILLSFENGANGIIETNRL 223
            ++T   V++VYA   +   P    A   D   +LL+ ++G        RL
Sbjct: 178 RWVTGREVVDVYAAGSDAGPPMFRAADDVDTGAVLLTLDDGTLATATAARL 228


>sp|O68965|MI2D_RHIME MYO-INOSITOL 2-DEHYDROGENASE >gi|3088561|gb|AAC70005.1| (AF059313)
           myo-inositol dehydrogenase [Sinorhizobium meliloti]
           Length = 330
           
 Score = 88.5 bits (216), Expect = 9e-17
 Identities = 79/331 (23%), Positives = 142/331 (42%), Gaps = 19/331 (5%)

Query: 1   MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELI 60
           +R G++G G++G  HA+  S  A      L+ VAD     A+ +A  +            
Sbjct: 3   VRFGLLGAGRIGKVHAKAVSGNAD---ARLVAVADAFPAAAEAIAGAYGCEVRTIDAIEA 59

Query: 61  KEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMVG 120
              +DAV I  PT  H ++   F     ++  EKPI    E  +  +K        LMVG
Sbjct: 60  AADIDAVVICTPTDTHADLIERFARAGKAIFCEKPIDLDAERVRACLKVVSDTKAKLMVG 119

Query: 121 HVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTRISDV----GVIIDLAVHDIDVM 176
              RF+P  + +++ I+ G +GE+  +T     P    +  +    G+  D+ +HD D+ 
Sbjct: 120 FNRRFDPHFMAVRKAIDDGRIGEVEMVTITSRDPSAPPVDYIKRSGGIFRDMTIHDFDMA 179

Query: 177 SFLTTSRVIEVYAKARNVKHPAKVE----DYALILLSFENGANGII-ETNRLTPHKTRTL 231
            FL     + V A A  +   A  +    D   ++L   +G   II  + R T    + +
Sbjct: 180 RFLLGEEPVSVTATAAVLIDKAIGDAGDYDSVSVILQTASGKQAIIANSRRATYGYDQRI 239

Query: 232 NVVGTEGIAYLDY---INQELTL---YNEEWIYKAKINK-EEPLKLEIEHFLECVKEGKK 284
            V G++G    +    ++ E+     Y    ++   + +  E    EIE F+  +++G +
Sbjct: 240 EVHGSKGAVAAENQRPVSIEIATGDGYTRPPLHDFFMTRYTEAYANEIESFIAAIEKGAE 299

Query: 285 PLVGGEEGLHALKVAVKALESSKKDEVVRVS 315
               G +GL AL +A  A+ S  +   + ++
Sbjct: 300 IAPSGNDGLAALALADAAVRSVAEKRQISIA 330


>sp|Q05184|PHT4_PSEPU PUTATIVE 4,5,-DIHYDROXYPHTHALATE DEHYDROGENASE (DHP DEHYDROGENASE)
           >gi|295711|dbj|BAA02512.1| (D13229) PHT4 [Pseudomonas
           putida]
           Length = 410
           
 Score = 85.0 bits (207), Expect = 1e-15
 Identities = 65/231 (28%), Positives = 97/231 (41%), Gaps = 13/231 (5%)

Query: 1   MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELI 60
           +R+GVVG+G+       +      + +V+L+G  D   +  ++    F   A++   +L 
Sbjct: 12  LRLGVVGLGRA---FTLMLPTFLADRRVQLVGACDPREQARRQFERDFDAPAYETIEDLA 68

Query: 61  KEG-VDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMV 119
            +  VDA+ IA P   H E T     N   VLVEKP+A S++    +I    +  V L+V
Sbjct: 69  ADSNVDALYIASPHQFHAEHTRIAAANRKHVLVEKPMALSLDECDRMIADCAEAGVKLIV 128

Query: 120 GHVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTR---------ISDVGVIIDLAV 170
           GH   F+   L+ +E I  G  G +  + A      + R             G +   A 
Sbjct: 129 GHCHSFDTPYLRTRELIGSGEFGAVKMIQALNYTDYLQRPRRPEELSTAEGGGAVFSQAA 188

Query: 171 HDIDVMSFLTTSRVIEVYAKARNVKHPAKVEDYALILLSFENGANGIIETN 221
           H +DV+  L  SR   V A   N       E      L FENGA   I  N
Sbjct: 189 HQVDVVRLLAGSRATRVRAAVGNWDPARPTEGAYTATLWFENGAFASITYN 239


>sp|Q54728|YJHC_STRPN HYPOTHETICAL PROTEIN IN NANB 3'REGION (ORF-5)
           >gi|1163116|gb|AAC44397.1| (U43526) ORF-5 [Streptococcus
           pneumoniae]
           Length = 347
           
 Score = 85.0 bits (207), Expect = 1e-15
 Identities = 69/264 (26%), Positives = 117/264 (44%), Gaps = 18/264 (6%)

Query: 1   MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELI 60
           ++ GVVG G  G   AR Y +     ++ L+   D     A+ +AE    +      EL+
Sbjct: 2   VKYGVVGAGYFGAELAR-YMQKNDGAEITLLYDPD----NAEAIAEELGAKVASSLDELV 56

Query: 61  K-EGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMV 119
             + VD V +A P +LH+E  +   ++  +V  EKPIA S +  +E++ A K+ NV  M 
Sbjct: 57  SSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCREMVDACKENNVTFMA 116

Query: 120 GHVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTRIS--------DVGVIIDLAVH 171
           GH+  F   V   KE I +G++G+++     R G    ++S          G  +   +H
Sbjct: 117 GHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQLSVSWKKIREKSGGHLYHHIH 176

Query: 172 DIDVMSFLTTSRVIEVYAKARNVKHPAK----VEDYALILLSFENGANGIIETNRLTPHK 227
           ++D + FL       V     NV H  +     +D   + + F N    ++E        
Sbjct: 177 ELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNMEFSNKRFALLEWGSAYRWG 236

Query: 228 TRTLNVVGTEGIAYLDYINQELTL 251
              + + G++G   LD  N + TL
Sbjct: 237 EHYVLIQGSKGAIRLDLFNCKGTL 260


>emb|CAC11912.1| (AL445065) hypothetical protein [Thermoplasma acidophilum]
           Length = 322
           
 Score = 82.7 bits (201), Expect = 5e-15
 Identities = 74/258 (28%), Positives = 114/258 (43%), Gaps = 30/258 (11%)

Query: 1   MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKT-----RAFKD 55
           M V ++G       HA  Y  L  E  V         ++R  +V E ++        + D
Sbjct: 6   MSVLLIGGNGFAKVHAETYRRLGIEFSV---------YDRNPQVLEMYRRDYGVRETYSD 56

Query: 56  YRELIKEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNV 115
               +    DAV I +P +LH EV M  IE    VLVEKP+   I+ A +II  AKK  +
Sbjct: 57  MAAALDADNDAVDIVLPHNLHYEVAMKAIEKGKHVLVEKPVTGRIDEAVKIINQAKKKRL 116

Query: 116 VLMVGHVERFNPAVLKLKETIERGMLGEIVTMTAK-----RVGPMVTRISDV--GVIIDL 168
             MV     F+P+  K  E ++ G +G++ T+  +           +R +++  G +ID 
Sbjct: 117 KFMVAEQFYFDPSFRKALEIVQSGKIGDVRTVIVRDQQRYDAPGWRSRKNEMMGGSLIDG 176

Query: 169 AVHDIDV-MSFLTTSRVIEVYAKARNVKHPAKV--EDYALILLSFENGANGII--ETNRL 223
            VH +++ + F    + I     A N K    +  ED    L +FEN  +GI     + +
Sbjct: 177 GVHFLEIFLDFGGQWKSI----SAHNYKGGTSIEGEDNTAALFTFENDVHGIFYYSWSYV 232

Query: 224 TPHKTRTLNVVGTEGIAY 241
            P K     V+GTEG  Y
Sbjct: 233 EPPKLPAFEVIGTEGSVY 250


>gb|AAG09709.1|AF218837_4 (AF218837) unknown [Pasteurella multocida]
           Length = 367
           
 Score = 82.3 bits (200), Expect = 6e-15
 Identities = 68/264 (25%), Positives = 121/264 (45%), Gaps = 18/264 (6%)

Query: 1   MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELI 60
           M+ GVVGVG  G   AR  +E  +  KV ++     + E  + +A+  +  A    ++L+
Sbjct: 2   MKYGVVGVGYFGADLARFMNE-NENAKVTMV----YDPENGETIAKELQCIAATSLKQLV 56

Query: 61  KEG-VDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMV 119
               VD V +A P  LH+E  ++  ++   V  EKPIA + +   E+++  ++  V+ M 
Sbjct: 57  SSPEVDCVIVATPNYLHKEPVIEAAKHGKHVFCEKPIALNYQDCDEMVRTCEENGVIFMA 116

Query: 120 GHVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTRIS--------DVGVIIDLAVH 171
           GHV  F   V   KE I++G++G+++   + R G    + S          G  +   +H
Sbjct: 117 GHVMNFFNGVHHAKELIKQGVIGKVLYCHSARNGWEDEQSSISWKKIRAKSGGHLYHHIH 176

Query: 172 DIDVMSFLTTSRVIEVYAKARNVKHPAK----VEDYALILLSFENGANGIIETNRLTPHK 227
           ++D + F+       V   A NV H ++     +D   + L FE G   ++E        
Sbjct: 177 ELDCIQFIMGGMPKTVTMTAGNVAHQSEKFGDEDDMLFLNLEFEGGRFAVLEWGSAFRWG 236

Query: 228 TRTLNVVGTEGIAYLDYINQELTL 251
              + + G +G   LD  + + TL
Sbjct: 237 EHYVLIQGEKGAIKLDMYHCKGTL 260


>sp|P09400|STRI_STRGR STREPTOMYCIN BIOSYNTHESIS PROTEIN STRI >gi|80803|pir||S17779 strI
           protein - Streptomyces griseus >gi|49268|emb|CAA68521.1|
           (Y00459) NAD:myo-inositol oxidoreductase [Streptomyces
           griseus]
           Length = 348
           
 Score = 82.3 bits (200), Expect = 6e-15
 Identities = 88/323 (27%), Positives = 137/323 (42%), Gaps = 25/323 (7%)

Query: 1   MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFER-AKEVAETFKTRAFKDYREL 59
           MRVG+VG G+MG  HAR   EL     + +  V      R A+E+A   K +   + REL
Sbjct: 1   MRVGIVGAGRMGRLHARTLLELPDPPDLVVHDVDPDGAHRLAQELAAGTKAQVTVE-REL 59

Query: 60  IK--EGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVL 117
                  DA+ +A P +  R   +      + V  EKP+      A E+++A    +  L
Sbjct: 60  ADTVTKADAIVVATPATQRRAPLLAAARAGLPVFCEKPLTADETEAAELVEAL--AHTRL 117

Query: 118 MVGHVERFNPAVLKLKETIERGMLGEI--VTMTAKRVGPMVTRISDVG--VIIDLAVHDI 173
            VG   R +P   +L+E I  G LG +  V  TA    P      +    +  D  +HDI
Sbjct: 118 HVGFQRRCDPEYQRLRELIAAGELGRVLLVRCTAFDHRPPADAYEETAGDIFTDCLIHDI 177

Query: 174 DVMSFLTTSRVIEVYAKARNVKHPAKVEDYALILLSFENGANGIIETNRLTPH-KTRTLN 232
           D + +LT    + V A    +       D A  +L+  +GA  ++  +RL PH     + 
Sbjct: 178 DAVHWLTGQPTVAVQADGARLL-AGSGYDVATAVLTLADGARAVLSASRLDPHGYDHRVE 236

Query: 233 VVGTEGIAYLDY-INQELTLYNEEW-----------IYKAKINK-EEPLKLEIEHFLECV 279
           V+GT+G   +       L L  ++             Y+   ++ E   + E+  F+  V
Sbjct: 237 VLGTKGSLSVGLDARTPLRLLGQDGTGCPPGPGAQPAYQDFTDRFEAAYRREVLAFVRTV 296

Query: 280 KEGKKPLVGGEEGLHALKVAVKA 302
            EG      G+E L A +VA  A
Sbjct: 297 TEGAPSPCTGQEALRAQRVAAAA 319


>pir||S70672 dehydrogenase homolog - Bordetella pertussis
           >gi|992971|emb|CAA62245.1| (X90711) gene referred to as
           bplA in Mol. Microbiol. 19:37-52(1996) [Bordetella
           pertussis] >gi|3451515|emb|CAA07671.1| (AJ007747)
           putative oxidoreductase [Bordetella bronchiseptica]
           >gi|1589221|prf||2210367C bplA gene [Bordetella
           pertussis]
           Length = 350
           
 Score = 82.3 bits (200), Expect = 6e-15
 Identities = 80/344 (23%), Positives = 148/344 (42%), Gaps = 44/344 (12%)

Query: 1   MRVGVVGVGKMGYHHARIYSELAKEG-KVELIGVADINFERAKEVAETFKTRAFKDYREL 59
           +R G+VG G++  +H      +A+ G + EL+ + D N E  +        R F    ++
Sbjct: 11  IRFGLVGCGRISKNHI---GAIAQHGDRAELVEICDTNPEALQAAEAATGARPFSSLSDM 67

Query: 60  IKEG-VDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLM 118
           + +G  DA+ +A P+ LH    ++  +    V+ EKP+A   E  + ++KA  +  V L 
Sbjct: 68  LAQGNADALVLATPSGLHPWQAIEVAQAGRHVVSEKPMATRWEDGKRMVKACDEAGVRLF 127

Query: 119 VGHVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTRIS--------------DVGV 164
           V    R N  +  +K+ IE+G  G I  +T   V    TR                D G 
Sbjct: 128 VVKQNRRNATLQLVKKAIEQGRFGRIYMVT---VNVFWTRPQEYYDAARWRGKWEWDGGA 184

Query: 165 IIDLAVHDIDVMSFLTTSRVIEVYAKARNVKHPAKVEDYALILLSFENGANGIIETNRLT 224
            ++ A H +D++ +L    V  VYA    +    + ED  +  L + +GA G I    LT
Sbjct: 185 FMNQASHYVDLLDWL-VGPVESVYAYTATLARRIEAEDTGVAALRWRHGAMGSINVTMLT 243

Query: 225 --PHKTRTLNVVGTEGIAYLDYINQELTLYNEEWIYKAKINKEEPLK------------- 269
              +   ++ ++G +G   +  +        +EW +      ++ ++             
Sbjct: 244 YPQNLEGSITILGEKGTVRVGGVAVNRI---DEWKFAEPHPDDDKIREANYETTSVYGFG 300

Query: 270 --LEIEHFLECVKEGKKPLVGGEEGLHALKVAVKALESSKKDEV 311
             L  ++ + C++   +P   G EGL +L + + A+  S +D V
Sbjct: 301 HPLYYDNVINCLRGDCEPETDGREGLQSLAL-LTAIYRSARDGV 343


>dbj|BAB05940.1| (AP001514) unknown conserved protein [Bacillus halodurans]
           Length = 345
           
 Score = 81.9 bits (199), Expect = 8e-15
 Identities = 78/335 (23%), Positives = 138/335 (40%), Gaps = 27/335 (8%)

Query: 1   MRVGVVGVGKMGYHHARI-----YSELAKEGKVELIGVADINFERAKEVAETFKTRAFKD 55
           + +G++G G++G  HA       Y EL     V+L  +     ER+ E+  T     F +
Sbjct: 4   VNIGLIGAGRIGQLHASNIISSPYMELKAVSDVQLDHLKGTEIERSVEIMTTNPDELFSN 63

Query: 56  YRELIKEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNV 115
                   +DA+ I   T  H             +  EKPI+  +   +  +    +  V
Sbjct: 64  ------RDIDAIFICSSTDTHAAFIKAAALAGKHIFCEKPISFHVTETKGALNIVNEAGV 117

Query: 116 VLMVGHVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTRISDV----GVIIDLAVH 171
              VG   R++    +++E ++ G +G    +      P    +S V    G+ +D+ +H
Sbjct: 118 KFQVGFNRRYDKHFRRVQECVQAGAIGAPHIIRVSSRDPEAPPLSYVERSGGMFMDMTIH 177

Query: 172 DIDVMSFLTTSRVIEVYAKARNVKHPAKVE----DYALILLSFENGANGIIETNRLTPH- 226
           D D++ +L+ S V EV  KA N+      E    D A+I L  ENGA  +I+ +R   + 
Sbjct: 178 DFDMVRYLSGSEVTEVSVKAANLVDSRIGEVGDVDTAIITLMLENGAIAVIDNSRQAAYG 237

Query: 227 KTRTLNVVGTEGIAYLDYINQELTLYNEEWIYKAKINK-------EEPLKLEIEHFLECV 279
             + + V G+ G    D   +     + +      + K       E+  K E+  F   +
Sbjct: 238 YDQRVEVFGSLGSVSADNERKTNVQISTKDTVTLDLPKHFFLDRYEQAYKDEVAEFATAI 297

Query: 280 KEGKKPLVGGEEGLHALKVAVKALESSKKDEVVRV 314
            E +     GE+G  A  +A+ A +S  ++  V V
Sbjct: 298 LEDQPLRCTGEDGYKAELLALAAKQSWLENRPVAV 332


>dbj|BAB06035.1| (AP001515) myo-inositol 2-dehydrogenase [Bacillus halodurans]
           Length = 348
           
 Score = 81.9 bits (199), Expect = 8e-15
 Identities = 81/302 (26%), Positives = 136/302 (44%), Gaps = 24/302 (7%)

Query: 1   MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRA--FKDYRE 58
           +R GV+G G +G  H +        GK+  + V D+N E AK+V    K  A  + D R 
Sbjct: 3   LRFGVIGTGAIGREHMKRIENKLSGGKI--VAVTDMNQEAAKQVVTQMKLEADVYPDDRS 60

Query: 59  LIK-EGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMN--- 114
           L+  + VDAV +      H    +  IE    V VEKP+A + E   +IIKA  +MN   
Sbjct: 61  LVAADNVDAVLVTSWGPAHEANVLAAIEAGKYVFVEKPLATTAEGCMKIIKA--EMNHGK 118

Query: 115 VVLMVGHVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMV--TRISDVGVIIDLAVHD 172
            ++ VG + R++   ++LK+ I+   +GE + +      P V  + I D+  I D  +H+
Sbjct: 119 RLVQVGFMRRYDKGYVQLKKAIDDHFIGEPLMVRCAHRNPEVGESYIDDM-AIHDTLIHE 177

Query: 173 IDVMSFLTTSRVIEVYAK-ARNVKHP-AKVEDYALILLSFENGANGIIETNRLTPHK--- 227
           IDV+ +L       V     +  KH    + D  ++ L  + G   +I        K   
Sbjct: 178 IDVLHWLIDDEYESVSVSFPKKTKHALPHLRDPRVVTLETKGGV--LITAEVFVNCKYGY 235

Query: 228 TRTLNVVGTEGIAYLDYIN----QELTLYNEEWIYKAKINKEEPLKLEIEHFLECVKEGK 283
                V+  EGIA L  ++    ++        +   K    E   +E++HF++ +K+  
Sbjct: 236 DIQCEVIREEGIASLPEVDSISFRKRATLGTNILMDWKQRFIEAYDVELQHFIDSIKQSG 295

Query: 284 KP 285
           +P
Sbjct: 296 EP 297


>gb|AAD51832.1|AF175299_7 (AF175299) ThuB [Sinorhizobium meliloti]
           Length = 365
           
 Score = 81.1 bits (197), Expect = 1e-14
 Identities = 71/252 (28%), Positives = 113/252 (44%), Gaps = 33/252 (13%)

Query: 1   MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTR-AFKDYREL 59
           MR+ ++G G M   HA+ ++E+  EG VE++G  D++  RAK  A T      F    + 
Sbjct: 6   MRLLILGTGGMANSHAKAFAEI--EG-VEMVGAVDVDPSRAKAFAVTHGIENTFTSLDDA 62

Query: 60  IKEG-VDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLM 118
           I  G  DA +   P   H   T+  I     VL EKP+AE+ E A E+  AA++  +V M
Sbjct: 63  IAWGEFDAATNVTPDKAHHPTTLALIAAGKHVLCEKPLAENYEKAAEMAAAAERAGLVTM 122

Query: 119 VGHVERFNPAVLKLKETIERGMLGEIVTMTA-------------------KRVGPMVTRI 159
           V    R    + K +E +  G +G +  + A                   K +  + T+ 
Sbjct: 123 VNLTYRNVAPLQKARELVVAGEIGRVRHLEASYLQSWLVSRAWGDWASESKWLWRLSTKH 182

Query: 160 SDVGVIIDLAVHDIDVMSFLTTSRVIEVYA--KARNVKHPAKVEDYAL-------ILLSF 210
              GV+ D+ +H +D   +   S V  V+A  KA +     ++ +Y L       +   F
Sbjct: 183 GSNGVLGDVGIHILDFAGYGANSSVERVFARLKAFDKAPDNRIGEYDLDANDSFAMTAEF 242

Query: 211 ENGANGIIETNR 222
           ENGA  +I  +R
Sbjct: 243 ENGAMAVIHASR 254


>emb|CAB88965.1| (AL353864) putative oxidoreductase. [Streptomyces coelicolor A3(2)]
           Length = 387
           
 Score = 79.2 bits (192), Expect = 6e-14
 Identities = 81/283 (28%), Positives = 116/283 (40%), Gaps = 41/283 (14%)

Query: 3   VGVVGVGKMGYHHARIYSELAKEG-----KVELIGVADINFERAKEVAETFK-TRAFKDY 56
           V VVG G MG  H + Y+ +         + EL+ VA+    RA+E A  F      +D+
Sbjct: 7   VAVVGFGWMGRVHTQAYARVRHHYPHLALRPELVTVAEEVPGRAEEAAAQFGFASTTRDW 66

Query: 57  RELIKEG-VDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNV 115
           RE+  +  V AVSI  P  LHRE+ +        + VEKP+  S + A+ +  A     V
Sbjct: 67  REVAADPRVHAVSITAPNFLHREIAVAMAGAGKHIWVEKPVGLSSDDARAVADAVSGAGV 126

Query: 116 VLMVGHVERFNPAVLKLKETIERGMLGEIV--------TMTAKRVGPMVTRI----SDVG 163
              VG   R  PAV   +  I  G +G +            A   G +  R        G
Sbjct: 127 QGAVGFNYRNAPAVETARRLIAAGEIGTVTHARLRFFSDYAAHPEGALTWRYERERGGSG 186

Query: 164 VIIDLAVHDIDVMSF-------LTTSRVIEVYAKARNVK-------------HPAKVEDY 203
           V+ DLA H  D+  F       LT    + V  +AR                 P + EDY
Sbjct: 187 VLGDLASHGADLARFLLGDIASLTADTAVFVPERARPASATAGHARATGGEPGPVENEDY 246

Query: 204 ALILLSFENGANGIIETNRLTPHKTRT--LNVVGTEGIAYLDY 244
              LL F +GA G++E  R++  +       V GT G  + D+
Sbjct: 247 VSCLLRFASGARGVLEACRVSVGEQNNYGFEVHGTTGAVFWDF 289


>gb|AAD03557.1| (AF095748) phthalate dihydrodiol dehydrogenase [Burkholderia
           cepacia]
           Length = 391
           
 Score = 78.8 bits (191), Expect = 7e-14
 Identities = 58/231 (25%), Positives = 95/231 (41%), Gaps = 13/231 (5%)

Query: 1   MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELI 60
           +R+GV G+G+     + +     ++ +V+L+   D   E  ++ A  F    + D  EL 
Sbjct: 6   LRIGVAGLGRA---FSLMLPTFLRDSRVQLVAACDPRDEARRQFAADFAAPTYADVAELA 62

Query: 61  KE-GVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMV 119
            +  V+ + +A P   H + T         VLVEKP+A +      +I A +  NV L+V
Sbjct: 63  NDPNVEIIYVASPHQFHAQHTEIAAAKGKHVLVEKPMALAAADCDRMIAACRAANVHLIV 122

Query: 120 GHVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTR---------ISDVGVIIDLAV 170
           GH   F+   L+ +E I  G  G +  + A      + R             G +   A 
Sbjct: 123 GHCHSFDTPYLRTRELISLGDFGAVKMIQAVNYTDYLYRPRRPEELATAEGGGAVFSQAA 182

Query: 171 HDIDVMSFLTTSRVIEVYAKARNVKHPAKVEDYALILLSFENGANGIIETN 221
           H +D++  L  SR   + A           E     L+ FENGA   +  N
Sbjct: 183 HQVDIVRMLAGSRATRLRASVGRWDPSRPTEGAYSALIWFENGAYASLSYN 233


>sp|P26935|MI2D_BACSU MYO-INOSITOL 2-DEHYDROGENASE >gi|80338|pir||JH0511 myo-inositol
           2-dehydrogenase (EC 1.1.1.18) iolG - Bacillus subtilis
           >gi|143086|gb|AAA22543.1| (M76431) inositol
           dehydrogenase [Bacillus subtilis]
           >gi|709987|dbj|BAA03296.1| (D14399) myo-inositol
           dehydrogenase [Bacillus subtilis]
           >gi|2636516|emb|CAB16006.1| (Z99124) myo-inositol
           2-dehydrogenase [Bacillus subtilis]
           Length = 344
           
 Score = 77.3 bits (187), Expect = 2e-13
 Identities = 66/253 (26%), Positives = 122/253 (48%), Gaps = 16/253 (6%)

Query: 1   MRVGVVGVGKMGYHHA-RIYSELAKEGKVELIGVADINFERAKEVAETFKTRAF---KDY 56
           +R+GV+G G +G  H  RI ++L+     E++ V D+N E A++V E ++  A     D 
Sbjct: 3   LRIGVIGTGAIGKEHINRITNKLSG---AEIVAVTDVNQEAAQKVVEQYQLNATVYPNDD 59

Query: 57  RELIKEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNV- 115
             L  E VDAV +      H    +  I+ +  V  EKP+A + E    I++   K+   
Sbjct: 60  SLLADENVDAVLVTSWGPAHESSVLKAIKAQKYVFCEKPLATTAEGCMRIVEEEIKVGKR 119

Query: 116 VLMVGHVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMV--TRISDVGVIIDLAVHDI 173
           ++ VG + R++   ++LKE ++  + GE + +      P V     +D+ V +D  VH+I
Sbjct: 120 LVQVGFMRRYDSGYVQLKEALDNHVNGEPLMIHCAHRNPTVGDNYTTDMAV-VDTLVHEI 178

Query: 174 DVMSFLTTS--RVIEVYAKARNVKHPAKVEDYALILLSFENG--ANGIIETNRLTPHKTR 229
           DV+ +L       ++V    ++      ++D  ++++  + G   N  I  N    +  +
Sbjct: 179 DVLHWLVNDDYESVQVIYPKKSKNALPHLKDPQIVVIETKGGIVINAEIYVNCKYGYDIQ 238

Query: 230 TLNVVGTEGIAYL 242
              +VG +GI  L
Sbjct: 239 -CEIVGEDGIIKL 250


>gb|AAC01706.1| (AF040570) unknown [Amycolatopsis mediterranei]
           Length = 342
           
 Score = 76.9 bits (186), Expect = 3e-13
 Identities = 73/289 (25%), Positives = 121/289 (41%), Gaps = 34/289 (11%)

Query: 40  RAKEVAETFKTRAFKDYRELIKEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAES 99
           R++E+A  F  +A     E + +G DAV I  PT+ H E+ +  I   V V+ EKP+A S
Sbjct: 52  RSRELAAEFGAKAAGSLEEAL-DGADAVDICTPTASHHEIALTAIAAGVGVVCEKPLAAS 110

Query: 100 IESAQEIIKAAKKMNVVLMVGHVERFNPAVLKLKETIERGMLGE----IVTMTAKRVGPM 155
            E A+EI+ AA++  V L   H  RF     +L E +  G LGE      + +A    P 
Sbjct: 111 AEEAEEIVTAAERAGVRLYAAHDVRFAAPYARLHELVASGRLGEGALGRFSFSAYHPRPW 170

Query: 156 VTRIS--DVGVIIDLAVHDIDVMSFLTTSRVIEVYAKAR-NVKHPA---KVEDYALILLS 209
               S    G++ D  +H  D+  ++    V+ V+A  + ++  PA    V     +L  
Sbjct: 171 TGHASARSGGILTDQLLHGADLAHWV-FGDVVRVHACYQGDIATPAPEGAVATGTAVLTH 229

Query: 210 FENGANGIIETNRLTPHK--TRTLNVVGTEGIAYLDYINQELTLYNEEWIYKAKI----- 262
                + ++     TP        +V GT G             Y+ EW  + ++     
Sbjct: 230 ASGAISQVVSRWTATPRPPVRVAFHVSGTGG----------SVSYDSEWPQEVRVVDGGA 279

Query: 263 -----NKEEPLKLEIEHFLECVKEGKKPLVGGEEGLHALKVAVKALESS 306
                        E+  F      G +P +G ++ L A+++   A ES+
Sbjct: 280 GNFAYGGPSVFDTEMREFATAFAGGPEPRIGAKDALAAVRIIHAAAESA 328


>emb|CAC11395.1| (AL445063) glucose-fructose oxidoreductase related protein
           [Thermoplasma acidophilum]
           Length = 322
           
 Score = 76.9 bits (186), Expect = 3e-13
 Identities = 60/228 (26%), Positives = 106/228 (46%), Gaps = 21/228 (9%)

Query: 1   MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKT-RAFKDYREL 59
           M + +VG    G  H RIYS+L  +     + + + +   AK  +E F+  + + +Y + 
Sbjct: 1   MDIVLVGCKGFGKEHLRIYSKLGYD-----VSIVERDSNEAKRCSELFRVYKVYDNYEDA 55

Query: 60  IKEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMV 119
           ++ G + V + VP  LH E+    ++++  +LVEKPI   I+S   +I+ A++  + LMV
Sbjct: 56  LRSGSNIVDLVVPDGLHYEMGSLALKSKKHLLVEKPITPDIDSGISLIQQAEESKLKLMV 115

Query: 120 GHVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTR-------ISDVGVIIDLAVHD 172
                F+P+V +    I  G +G+  T+  +       +       +   G++ID   H 
Sbjct: 116 AEQFYFDPSVNEAIRRINNGEIGKPHTVIVRHQSFRELKGWRNEKSMMGRGILIDEGTHY 175

Query: 173 IDVMSFLTTSRVIEVYAKARNVKHPA---KVEDYALILLSFENGANGI 217
           ID     T       Y   R+  H       ED A  + +FENG +G+
Sbjct: 176 ID-----TLLNFGGRYRSLRSFVHRTWDFLGEDTAEAVFNFENGMHGL 218


>pir||T36464 probable oxidoreductase - Streptomyces coelicolor
           >gi|5824085|emb|CAB54161.1| (AL110470) putative
           oxidoreductase [Streptomyces coelicolor A3(2)]
           Length = 417
           
 Score = 76.1 bits (184), Expect = 5e-13
 Identities = 65/287 (22%), Positives = 116/287 (39%), Gaps = 53/287 (18%)

Query: 1   MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKD--YRE 58
           +RVGVVGVG+     A + + + + G   ++  AD +    ++    F         Y  
Sbjct: 12  LRVGVVGVGQ----RADMAALVNRSGAARIVSCADPDPRGREDARRLFGADVVVHDRYER 67

Query: 59  LIKEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLM 118
           ++ + +DAV +  P  LH E  + F+   V+V VEKP+  ++     ++ AA +    L 
Sbjct: 68  MLDDELDAVFVLTPDHLHTEPALCFLAAGVAVFVEKPLTITVADCDALLMAAFRSRTRLY 127

Query: 119 VGHVERFNPAVLKLKETIERGMLGEIVTMTAKR-VGP---------MVTRISDVGVIIDL 168
           VGH  R  P + +++E I+ G +G +  +  +  VG             R +  G+++  
Sbjct: 128 VGHNLRHLPVLRRMRELIDDGAVGRVRAVWCRHFVGHGGDFYFKDWHAQRANTTGLLLQK 187

Query: 169 AVHDIDVMSFL--------TTSRVIEVY-----------------------------AKA 191
             HD+DV+ +L             + VY                             +  
Sbjct: 188 GAHDLDVVHWLAGGFSRNVVAQGALAVYGDNPRRATQETVPPGQRMPDWFDPEVWPPSAL 247

Query: 192 RNVKHPAKVEDYALILLSFENGANGIIETNRLTPHKTRTLNVVGTEG 238
           R++     VED +++L   +NG     +    TP   R   V+G EG
Sbjct: 248 RDLNPVVDVEDISMMLARLDNGVLASYQQCHFTPDYWRNYTVIGDEG 294


>pir||A71443 probable inositol 2-dehydrogenase - Arabidopsis thaliana
           >gi|2245096|emb|CAB10518.1| (Z97343) inositol
           2-dehydrogenase like protein [Arabidopsis thaliana]
           >gi|7268489|emb|CAB78740.1| (AL161546) inositol
           2-dehydrogenase like protein [Arabidopsis thaliana]
           Length = 364
           
 Score = 76.1 bits (184), Expect = 5e-13
 Identities = 65/242 (26%), Positives = 119/242 (48%), Gaps = 26/242 (10%)

Query: 2   RVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFER---AKEVAETF--KTRAFKDY 56
           + G+VG+G MG  H      L  +G + ++ +AD +      A E+A++F  + + F  +
Sbjct: 11  KYGIVGIGMMGREHLINLHHLRDQG-LAVVCIADPHPPSQLLAIELAQSFGWELKVFSGH 69

Query: 57  RELIK-EGVDAVSIAVPTSLHREVTMDFIENEVS--VLVEKPIAESIESAQEIIKAAKK- 112
            EL+K E  D + ++ P   H ++ MD I       VLVEKP+  ++   +++++AAKK 
Sbjct: 70  EELLKSELCDVIVVSSPNMTHHQILMDIINYSKPHHVLVEKPLCTTVADCKQVLEAAKKR 129

Query: 113 MNVVLMVGHVERFNPAVLKLKETIERGMLGEIVTMTAKRVG--PMVTRIS----DVGVII 166
            ++V+ VG   R+ P V KL E ++    G  V M A R    P + ++      +  ++
Sbjct: 130 SDMVVQVGLEYRYMPPVAKLIEQVKGRDFGN-VKMVAIREHRFPFLVKVGLNKMGLWTLV 188

Query: 167 DLAVHDIDVMSFLTTSRVIEVYAK-ARNVKHPAKVE--------DYALILLSFENGANGI 217
           +   H  D+M     +  + V A    +V H  +V         D A +++ F+NG  G+
Sbjct: 189 EKCCHFFDLMRLFAGANPVCVMASGGMDVNHKDEVYGGKVPDIIDNAYVIIEFDNGCRGM 248

Query: 218 IE 219
           ++
Sbjct: 249 LD 250


>gb|AAC71791.1| (M77665) qutH [Aspergillus nidulans]
           Length = 398
           
 Score = 74.9 bits (181), Expect = 1e-12
 Identities = 68/258 (26%), Positives = 112/258 (43%), Gaps = 44/258 (17%)

Query: 5   VVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELIKE-- 62
           +VG G +G  HA+    + +  + +LI   D +   A  VAE+F    +     ++    
Sbjct: 16  IVGAGLIGPRHAQ---SVQRHPRTQLIAFVDPS-PSAIPVAESFGVPCYDSITSMLDVVG 71

Query: 63  ----GVDAVSIAVPTSLHREVTMDFIENEV-SVLVEKPIAESIESAQEII---------- 107
                 DA  ++ P   H +VT+  +EN + ++L+EKPI++ +ESA+ ++          
Sbjct: 72  KTTGKPDAAIVSTPNHTHVDVTLQLLENGIRNILLEKPISDDLESAEHLLATVKEQKCKD 131

Query: 108 -KAAKKMNVVLMVGHVERFNPAVLKLKETIERGMLGEIVTMT------------AKRVGP 154
            K  K   + + +GH  RFNP +   K  +E   LG +V +             A  +G 
Sbjct: 132 EKRGKDAKINIQIGHHRRFNPYIQTTKSLLETDSLGTVVAVNGLWTLLKPASYFAPPLGS 191

Query: 155 MVTRISDVGVIIDLAVHDIDVMSFLTTSRVIEVYAKA-------RNVKHPAKVEDYALIL 207
                   GV+    +HDIDV+ FL    V  VYA+        +N +H A  E+   + 
Sbjct: 192 WRADKKKGGVLGINLIHDIDVLQFL-FGPVSRVYAEGTLLQRMRQNPEHTA--EEGCAVT 248

Query: 208 LSFENGANGIIETNRLTP 225
           L F +G  G       TP
Sbjct: 249 LRFASGIVGTFLICDATP 266


>emb|CAC12307.1| (AL445066) glucose-fructose oxidoreductase related protein
           [Thermoplasma acidophilum]
           Length = 321
           
 Score = 74.9 bits (181), Expect = 1e-12
 Identities = 62/255 (24%), Positives = 107/255 (41%), Gaps = 30/255 (11%)

Query: 1   MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTR-----AFKD 55
           M+V ++G+   G  H   +S+L  + ++          ER  EV     +R         
Sbjct: 1   MKVNIIGLNGFGKRHIEAWSKLDVDIEIT---------ERKAEVVRDLLSRYDIVKVNSS 51

Query: 56  YRELIKEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNV 115
             E      +   + +P +LH +VT+  +     V+VEKPIA  I  A+E+I+ A +   
Sbjct: 52  LEEAFNSDAEIFDLVLPHNLHHDVTVKSLAMGKHVMVEKPIATDISDAREMIRTAVQNRR 111

Query: 116 VLMVGHVERFNPAVLKLKETIERGMLGEIVTMTAK-------RVGPMVTRISDVGVIIDL 168
             MV     F+P+V K KE ++ G +G + T+  +               I   G +ID 
Sbjct: 112 KFMVADQYYFDPSVWKAKEIMDSGKIGSVHTIIIRDQRKYNWHGWRSQASIMGGGPLIDG 171

Query: 169 AVHDIDVMSFLTTSRV---IEVYAKARNVKHPAKVEDYALILLSFENGANGII--ETNRL 223
            +H ID M  L    +      Y    +++ P  VE     +  F++G+NG+        
Sbjct: 172 GIHFIDTMLNLAGEYISVRSNFYRSVASIEEPDTVE----AIFKFKDGSNGLFFYSWGYP 227

Query: 224 TPHKTRTLNVVGTEG 238
            P    +  ++GT+G
Sbjct: 228 YPPSLPSFEIIGTDG 242


>pir||A69834 conserved hypothetical protein yhjJ - Bacillus subtilis
           >gi|2226182|emb|CAA74472.1| (Y14081) hypothetical
           protein [Bacillus subtilis] >gi|2633389|emb|CAB12893.1|
           (Z99109) similar to hypothetical proteins [Bacillus
           subtilis]
           Length = 350
           
 Score = 74.1 bits (179), Expect = 2e-12
 Identities = 66/230 (28%), Positives = 108/230 (46%), Gaps = 23/230 (10%)

Query: 2   RVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELIK 61
           ++G++G G +   HA   S +      EL+GV DIN + A+   +TF  ++F++  ELI 
Sbjct: 3   KIGIIGAGGIARAHATALSTIKN---AELVGVYDINQQNAESFVKTFGGKSFENVDELI- 58

Query: 62  EGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMVGH 121
           +  + + +A P   H+E  +  +     VL EKP+A S+E A  +   A++++V   +G 
Sbjct: 59  DASEGLIVASPNFCHKEHALQALGKHKHVLCEKPMAISLEEASIMKDTAERLSVRASMGF 118

Query: 122 VERFNPAVLKLKETIERGMLGEIVTM-------TAKRVGPMVTR-----ISDVGVIIDLA 169
             R+   V  LK  I    LG I+++       +A R      R         G + DL 
Sbjct: 119 NYRYLSYVNILKSLIINNELGNILSIKVHFKKNSALRRKKFTWRDDANSKKTSGSLGDLG 178

Query: 170 VHDIDVMSFLTTSRVIEVYAKAR---NVK----HPAKVEDYALILLSFEN 212
           +H ID++ +L  S  I    +A+   NVK        V+DYA I     N
Sbjct: 179 IHLIDMVWYLFESDFITESVRAKMNTNVKTKEDKQVLVDDYAEIYGQLRN 228


>emb|CAB02496.1| (Z80356) glucose-fructose oxidoreductase [Zymomonas mobilis]
           Length = 433
           
 Score = 73.4 bits (177), Expect = 3e-12
 Identities = 77/334 (23%), Positives = 146/334 (43%), Gaps = 36/334 (10%)

Query: 5   VVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETF-----KTRAFKDYREL 59
           +VG+GK   +         +  ++E +     N E+AK VA  +     K   + ++ ++
Sbjct: 88  IVGLGKYALNQILPGFAGCQHSRIEAL--VSGNAEKAKIVAAEYGVDPRKIYDYSNFDKI 145

Query: 60  IKEG-VDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLM 118
            K+  +DAV I +P SLH E  +   +    V+ EKP+A S+   Q +I AAK  N  LM
Sbjct: 146 AKDPKIDAVYIILPNSLHAEFAIRAFKAGKHVMCEKPMATSVADCQRMIDAAKAANKKLM 205

Query: 119 VG---HVERFNPAVLKLKETIERGMLGEIVTMTAKRVGP--------MVTRISDVGVIID 167
           +G   H +  N A +KL    + G LG + T  +  +          +   ++  G ++D
Sbjct: 206 IGYRCHYDPMNRAAVKLIRENQLGKLGMVTTDNSDVMDQNDPAQQWRLRRELAGGGSLMD 265

Query: 168 LAVHDIDVMSFLTTSRVIEVYA---KARNVKHPAKVEDYALILLSFENGA--NGIIETNR 222
           + ++ ++   +L     IEV A      N +   +VED  +  + F +GA  +G    + 
Sbjct: 266 IGIYGLNGTRYLLGEEPIEVRAYTYSDPNDERFVEVEDRIIWQMRFRSGALSHGASSYST 325

Query: 223 LTPHKTRTLNVVGTEGIAYLD----YINQELTLY-----NEEWIYKAKINKEEPLKLEIE 273
            T   T   +V G + +  +D    Y    +++      N+  + +  +        +++
Sbjct: 326 TT---TSRFSVQGDKAVLLMDPATGYYQNLISVQTPGHANQSMMPQFIMPANNQFSAQLD 382

Query: 274 HFLECVKEGKKPLVGGEEGLHALKVAVKALESSK 307
           H  E V   K     GEEG+  +++     E+++
Sbjct: 383 HLAEAVINNKPVRSPGEEGMQDVRLIQAIYEAAR 416


>pdb|1OFG|A Chain A, Glucose-Fructose Oxidoreductase >gi|2098324|pdb|1OFG|B
           Chain B, Glucose-Fructose Oxidoreductase
           >gi|2098325|pdb|1OFG|C Chain C, Glucose-Fructose
           Oxidoreductase >gi|2098326|pdb|1OFG|D Chain D,
           Glucose-Fructose Oxidoreductase >gi|2098327|pdb|1OFG|E
           Chain E, Glucose-Fructose Oxidoreductase
           >gi|2098328|pdb|1OFG|F Chain F, Glucose-Fructose
           Oxidoreductase
           Length = 381
           
 Score = 73.4 bits (177), Expect = 3e-12
 Identities = 77/334 (23%), Positives = 146/334 (43%), Gaps = 36/334 (10%)

Query: 5   VVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETF-----KTRAFKDYREL 59
           +VG+GK   +         +  ++E +     N E+AK VA  +     K   + ++ ++
Sbjct: 36  IVGLGKYALNQILPGFAGCQHSRIEAL--VSGNAEKAKIVAAEYGVDPRKIYDYSNFDKI 93

Query: 60  IKEG-VDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLM 118
            K+  +DAV I +P SLH E  +   +    V+ EKP+A S+   Q +I AAK  N  LM
Sbjct: 94  AKDPKIDAVYIILPNSLHAEFAIRAFKAGKHVMCEKPMATSVADCQRMIDAAKAANKKLM 153

Query: 119 VG---HVERFNPAVLKLKETIERGMLGEIVTMTAKRVGP--------MVTRISDVGVIID 167
           +G   H +  N A +KL    + G LG + T  +  +          +   ++  G ++D
Sbjct: 154 IGYRCHYDPMNRAAVKLIRENQLGKLGMVTTDNSDVMDQNDPAQQWRLRRELAGGGSLMD 213

Query: 168 LAVHDIDVMSFLTTSRVIEVYA---KARNVKHPAKVEDYALILLSFENGA--NGIIETNR 222
           + ++ ++   +L     IEV A      N +   +VED  +  + F +GA  +G    + 
Sbjct: 214 IGIYGLNGTRYLLGEEPIEVRAYTYSDPNDERFVEVEDRIIWQMRFRSGALSHGASSYST 273

Query: 223 LTPHKTRTLNVVGTEGIAYLD----YINQELTLY-----NEEWIYKAKINKEEPLKLEIE 273
            T   T   +V G + +  +D    Y    +++      N+  + +  +        +++
Sbjct: 274 TT---TSRFSVQGDKAVLLMDPATGYYQNLISVQTPGHANQSMMPQFIMPANNQFSAQLD 330

Query: 274 HFLECVKEGKKPLVGGEEGLHALKVAVKALESSK 307
           H  E V   K     GEEG+  +++     E+++
Sbjct: 331 HLAEAVINNKPVRSPGEEGMQDVRLIQAIYEAAR 364


>sp|Q07982|GFO_ZYMMO GLUCOSE--FRUCTOSE OXIDOREDUCTASE PRECURSOR (GFOR)
           >gi|95542|pir||A42289 glucose-fructose oxidoreductase
           (EC 1.1.-.-) precursor - Zymomonas mobilis
           >gi|155588|gb|AAA27690.1| (M97379) glucose-fructose
           oxidoreductase [Zymomonas mobilis]
           Length = 439
           
 Score = 72.6 bits (175), Expect = 5e-12
 Identities = 74/304 (24%), Positives = 133/304 (43%), Gaps = 33/304 (10%)

Query: 39  ERAKEVAETF-----KTRAFKDYRELIKEG-VDAVSIAVPTSLHREVTMDFIENEVSVLV 92
           E+AK VA  +     K   + ++ ++ K+  +DAV I +P SLH E  +   +    V+ 
Sbjct: 119 EKAKIVAAEYGVDPRKIYDYSNFDKIAKDPKIDAVYIILPNSLHAEFAIRSFKAGKHVMC 178

Query: 93  EKPIAESIESAQEIIKAAKKMNVVLMVG---HVERFNPAVLKLKETIERGMLGEIVTMTA 149
           EKP+A S+   Q +I AAK  N  LM+G   H +  N A +KL    + G LG + T  +
Sbjct: 179 EKPMATSVADCQRMIDAAKAANKKLMIGYRCHYDPMNRAAVKLIRENQLGKLGMVTTDNS 238

Query: 150 KRVGPMVTRISDV-------GVIIDLAVHDIDVMSFLTTSRVIEVYA---KARNVKHPAK 199
             +       S V       G ++D+ ++ ++   +L     IEV A      N +   +
Sbjct: 239 DVMDQNDLHSSGVCVVNSGGGSLMDIGIYGLNGTRYLLGEEPIEVRAYTYSDPNDERFVE 298

Query: 200 VEDYALILLSFENGA--NGIIETNRLTPHKTRTLNVVGTEGIAYLD----YINQELTLY- 252
           VED  +  + F +GA  +G    +  T   T   +V G + +  +D    Y    +++  
Sbjct: 299 VEDRIIWQMRFRSGALSHGASSYSTTT---TSRFSVQGDKAVLLMDPATGYYQNLISVQT 355

Query: 253 ----NEEWIYKAKINKEEPLKLEIEHFLECVKEGKKPLVGGEEGLHALKVAVKALESSKK 308
               N+  + +  +        +++H  E V   K     GEEG+  +++     E+++ 
Sbjct: 356 PGHANQSMMPQFIMPANNQFSAQLDHLAEAVINNKPVRSPGEEGMQDVRLIQAIYEAART 415

Query: 309 DEVV 312
              V
Sbjct: 416 GRAV 419


>pir||A72379 hypothetical protein TM0425 - Thermotoga maritima (strain MSB8)
           >gi|4980931|gb|AAD35510.1|AE001721_9 (AE001721)
           oxidoreductase, putative [Thermotoga maritima]
           Length = 328
           
 Score = 72.6 bits (175), Expect = 5e-12
 Identities = 75/295 (25%), Positives = 140/295 (47%), Gaps = 31/295 (10%)

Query: 42  KEVAE-TFKTRAFKDYRELI-KEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAES 99
           K ++E   K + + ++ E++ KE  D + I    SL+ ++ ++ +E ++   VEKPIA +
Sbjct: 43  KAISEMNIKPKKYNNWWEMLEKEKPDILVINTVFSLNGKILLEALERKIHAFVEKPIATT 102

Query: 100 IESAQEIIKAAKKM--NVVLMVGHVERFNPAVLKLKETIERGMLGEI---VTMTAKRVGP 154
            E  ++I    +K+   V        R+ P  L  K+ +  G +GEI    T  + ++G 
Sbjct: 103 FEDLEKIRSVYQKVRNEVFFTAMFGIRYRPHFLTAKKLVSEGAVGEIRLVNTQKSYKLGQ 162

Query: 155 ----MVTRISDVGVIIDLAVHDIDVMSFLTTSRVIEVYA---KARNVKHPAKVEDYALIL 207
                  R +  G I  + +H ID + ++T  + + VYA   +  N  H  ++E  AL  
Sbjct: 163 RPDFYKKRETYGGTIPWVGIHAIDWIHWITGKKFLSVYATHSRLHNSGH-GELETTALCH 221

Query: 208 LSFENGANGIIETNRLTP-----HKTRTLNVVGTEGIAYLDYINQELTLYNEEWIYKAKI 262
            + EN     +  + L P     H    + +VGT GI  ++ IN+ + L +E      K 
Sbjct: 222 FTLENEVFASLSIDYLRPQGAPTHDDDRMRIVGTRGI--VEVINERVFLTDE------KG 273

Query: 263 NKEEPLKLE---IEHFLECVKEGKKPLVGGEEGLHALKVAVKALESSKKDEVVRV 314
           ++E PL  +    E FL  ++   K +V  E+ +   ++A+KA  S+   ++V +
Sbjct: 274 HREVPLVEKGQIFEDFLREIRGQGKCMVTPEDSILTTEIALKARLSADTGQIVLI 328


>pir||S56505 hypothetical 41.9K protein (leuX-fecE intergenic region) -
           Escherichia coli >gi|537121|gb|AAA97176.1| (U14003)
           ORF_o377 [Escherichia coli] >gi|1790731|gb|AAC77236.1|
           (AE000498) putative dehydrogenase [Escherichia coli K12]
           Length = 377
           
 Score = 72.2 bits (174), Expect = 7e-12
 Identities = 47/151 (31%), Positives = 73/151 (48%), Gaps = 6/151 (3%)

Query: 4   GVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELIKEG 63
           GVVGVG  G   AR +  +    K+  +     + E  + +A   +         L+   
Sbjct: 10  GVVGVGYFGAELAR-FMNMHDNAKITCV----YDPENGENIARELQCINMSSLDALVSSK 64

Query: 64  -VDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMVGHV 122
            VD V +A P  LH+E  +   +N+  V  EKPIA S E   +++KA K+  V  M GH+
Sbjct: 65  LVDCVIVATPNYLHKEPVIKAAKNKKHVFCEKPIALSYEDCVDMVKACKEAGVTFMAGHI 124

Query: 123 ERFNPAVLKLKETIERGMLGEIVTMTAKRVG 153
             F   V   ++ I+ G++GEI++   KR G
Sbjct: 125 MNFFNGVQYARKLIKEGVIGEILSCHTKRNG 155


>sp|P39353|YJHC_ECOLI HYPOTHETICAL 41.4 KD PROTEIN IN LEUX-FECE INTERGENIC REGION
           Length = 372
           
 Score = 72.2 bits (174), Expect = 7e-12
 Identities = 47/151 (31%), Positives = 73/151 (48%), Gaps = 6/151 (3%)

Query: 4   GVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYRELIKEG 63
           GVVGVG  G   AR +  +    K+  +     + E  + +A   +         L+   
Sbjct: 5   GVVGVGYFGAELAR-FMNMHDNAKITCV----YDPENGENIARELQCINMSSLDALVSSK 59

Query: 64  -VDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMVGHV 122
            VD V +A P  LH+E  +   +N+  V  EKPIA S E   +++KA K+  V  M GH+
Sbjct: 60  LVDCVIVATPNYLHKEPVIKAAKNKKHVFCEKPIALSYEDCVDMVKACKEAGVTFMAGHI 119

Query: 123 ERFNPAVLKLKETIERGMLGEIVTMTAKRVG 153
             F   V   ++ I+ G++GEI++   KR G
Sbjct: 120 MNFFNGVQYARKLIKEGVIGEILSCHTKRNG 150


>pir||T50594 probable oxidoreductase [imported] - Streptomyces coelicolor
           >gi|6469270|emb|CAB61731.1| (AL133220) putative
           oxidoreductase. [Streptomyces coelicolor A3(2)]
           Length = 351
           
 Score = 72.2 bits (174), Expect = 7e-12
 Identities = 72/248 (29%), Positives = 109/248 (43%), Gaps = 17/248 (6%)

Query: 1   MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKT-RAFKDYREL 59
           +R G++  G M    AR  ++L      E++ VA      AK  AE F   RA+  +  L
Sbjct: 9   VRWGILATGGMA---ARFTADLVDLPDAEVVAVASRTEASAKTFAERFGIPRAYGGWETL 65

Query: 60  IK-EGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLM 118
            + E VD V +A P S HR      +E   +VL EKP   +   A E++  A++  V LM
Sbjct: 66  ARDEDVDVVYVATPHSAHRTAAGLCLEAGRNVLCEKPFTLNAREAAELVALARENGVFLM 125

Query: 119 VGHVERFNPAVLKLKETIERGMLGEIVTMTAK--RVGPM--VTRISDV----GVIIDLAV 170
                  NP V +LKE +  G +GE+ ++ A     GP     R+ D     G ++DL V
Sbjct: 126 EAMWMYCNPLVRRLKELVADGAIGEVRSLQADFGLAGPFPAAHRLRDPAQGGGALLDLGV 185

Query: 171 HDIDVMSFLTTSRVIEVYAKARNVKHPAKVEDYALILLSFENGANGIIETNRLTPHKTRT 230
           + +     L           AR V     V+     LLS+ N A   I  + +T     +
Sbjct: 186 YPVSFAQLLLGE---PTDVAARAVLSEEGVDLQTGALLSYGNDALASIHCS-ITGGTPNS 241

Query: 231 LNVVGTEG 238
            ++ G+EG
Sbjct: 242 ASITGSEG 249


>sp|P77503|YCJS_ECOLI HYPOTHETICAL 38.7 KD PROTEIN IN PSPE-OMPG INTERGENIC REGION
           >gi|7467124|pir||F64880 ycjS protein - Escherichia coli
           >gi|1742152|dbj|BAA14890.1| (D90769) Rhizopine
           catabolism protein MocA. [Escherichia coli]
           >gi|1742160|dbj|BAA14897.1| (D90770) Rhizopine
           catabolism protein MocA. [Escherichia coli]
           >gi|1787574|gb|AAC74397.1| (AE000229) putative
           dehydrogenase [Escherichia coli K12]
           Length = 351
           
 Score = 71.8 bits (173), Expect = 9e-12
 Identities = 53/191 (27%), Positives = 90/191 (46%), Gaps = 15/191 (7%)

Query: 1   MRVGVVGVGKMGYH-HARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYREL 59
           +RV ++G G++    HA  Y        +EL+ V D    +A+ +AE +   +  D  + 
Sbjct: 10  LRVAIIGAGQVADKVHASYY---CTRNDLELVAVCDSRLSQAQALAEKYGNASVWDDPQA 66

Query: 60  IKEGV--DAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVL 117
           +   V  D VS+  P   H E T+  +E    V+ EKP A + E A+E+   A+K+  VL
Sbjct: 67  MLLAVKPDVVSVCSPNRFHYEHTLMALEAGCHVMCEKPPAMTPEQAREMCDTARKLGKVL 126

Query: 118 MVGHVERFNPAVLKLKETIERGMLGEIVTMTAKRV--------GPMVTR-ISDVGVIIDL 168
                 RF     +L+E +  G+LGEI   TA+ +        G    + +   G +ID+
Sbjct: 127 AYDFHHRFALDTQQLREQVTNGVLGEIYVTTARALRRCGVPGWGVFTNKELQGGGPLIDI 186

Query: 169 AVHDIDVMSFL 179
            +H +D   ++
Sbjct: 187 GIHMLDAAMYV 197


>pir||G72391 conserved hypothetical protein - Thermotoga maritima (strain MSB8)
           >gi|4980813|gb|AAD35400.1|AE001713_4 (AE001713)
           conserved hypothetical protein [Thermotoga maritima]
           Length = 328
           
 Score = 71.0 bits (171), Expect = 2e-11
 Identities = 75/298 (25%), Positives = 125/298 (41%), Gaps = 25/298 (8%)

Query: 1   MRVGVVGVGKMGYH-HARIYSELAKEGKVELIGVADINFERAKEVAETFKTRA-FKDYRE 58
           +R+G+VG G      H      L+     E+  V       A+E A+     A F  Y E
Sbjct: 7   IRLGIVGCGIAARELHLPALKNLSH--LFEITAVTSRTRSHAEEFAKMVGNPAVFDSYEE 64

Query: 59  LIKEG-VDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVL 117
           L++ G VDAV + +P  L+       +   V V+ EKPI+  +E+ +++++ ++K    +
Sbjct: 65  LLESGLVDAVDLTLPVELNLPFIEKALRKGVHVICEKPISTDVETGKKVVELSEKSEKTV 124

Query: 118 MVGHVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTRISDV------------GVI 165
            +    R  PA  K KE +E G +G+ V M  +    M      V            G +
Sbjct: 125 YIAENFRHVPAFWKAKELVESGAIGDPVFMNWQIWVGMDENNKYVHTDWRKKPKHVGGFL 184

Query: 166 IDLAVHDIDVMSFLTTSRVIEVYAKARNVKHPAKVEDYALILLSFENGANGIIETNRLTP 225
            D  VH    M  L    +  + A A+++       D+   +  FENG  G    +    
Sbjct: 185 SDGGVHHAAAMR-LILGEIEWISAVAKDLSPLLGGMDFLSSIFEFENGTVGNYTISYSLK 243

Query: 226 HKTRTLNVVGTEGIAYLDYINQELTLYNEEWIYKAKINKEEPLKLEIEHFLECVKEGK 283
              R   + GT+G   + +   +  + NEE   + K+ +E   + E E F + V EGK
Sbjct: 244 GNER-FEITGTKGKISISW---DKIVLNEE---EMKVPQENSYQKEFEDFYQVVAEGK 294


>gb|AAK43115.1| Dehydrogenase, putative [Sulfolobus solfataricus]
           Length = 319
           
 Score = 70.6 bits (170), Expect = 2e-11
 Identities = 85/324 (26%), Positives = 134/324 (41%), Gaps = 28/324 (8%)

Query: 1   MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRA-FKDYREL 59
           M++ VVG    G  H R    ++    +E   V   N E+A+E  + F     F  Y ++
Sbjct: 1   MKIAVVGCDGFGKVHLRAMRNISG---IEYY-VFSRNEEKARECMKEFNAEGYFTRYEDV 56

Query: 60  IKEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMV 119
           IK  VD V + V    H  + +  ++    +++EKPIA +IE A  +I  +K      MV
Sbjct: 57  IKSNVDIVDLLVSHDQHYPMGVMAMKAGKHLMLEKPIARTIEEAMGLINTSKDTKRKFMV 116

Query: 120 GHVERFNPAVLKLKETIER-GMLGEIVTMTAKRVGPMVTRISDV----GVIIDLAVHDID 174
                F  +V K KE + R G L  I+  +     P   R        G +ID  VH ID
Sbjct: 117 LEQFYFESSVRKAKELLPRLGNLSLIIVRSIHLYQPKGWRREKEKMGGGALIDGGVHFID 176

Query: 175 VMSFLTTSRVIEVYAKARNV--KHPAKV--EDYALILLSFENGANGIIETNRLTPH--KT 228
            +  L        Y   R V  K+ + +  ED  L  L F  G  G++  +  TP+  K 
Sbjct: 177 TLLNLGGE-----YESVRGVCGKYFSGIEGEDLTLATLRFRKGHLGLLMYSWTTPNPPKV 231

Query: 229 RTLNVVGTEGIAYLDYINQ-------ELTLYNEEWIYKAKINKEEPLKLEIEHFLECVKE 281
               + G  G    D   +       +L L  +    + ++ K  P++ EI  F++ VK 
Sbjct: 232 PAFEIYGENGSIIEDPNTRVMGKAYGDLILNVDGKEERIEVEKVNPIEEEIRGFVKAVKN 291

Query: 282 GKKPLVGGEEGLHALKVAVKALES 305
             +  +  E  L  LK  +   +S
Sbjct: 292 NTEVPMPPEIALRDLKAVLDIYKS 315


>dbj|BAA83485.1| (AB021928) dimeric dihydrodiol dehydrogenase [Oryctolagus
           cuniculus]
           Length = 329
           
 Score = 70.2 bits (169), Expect = 3e-11
 Identities = 69/276 (25%), Positives = 128/276 (46%), Gaps = 23/276 (8%)

Query: 29  ELIGVADINFERAKEVAETFKT-RAFKDYRELIKE-GVDAVSIAVPTSLHREVTMDFIEN 86
           +++ VA  +  RA+E A T    +A+  Y EL K+  V+   I      H+   + F+  
Sbjct: 24  QVVAVAARDLRRAEEFARTHGIPKAYGSYEELAKDPDVEVAYIGTQHPQHKAAVLLFLAA 83

Query: 87  EVSVLVEKPIAESIESAQEIIKAAKKMNVVLMVGHVERFNPAVLKLKETIERGMLGEIVT 146
             +VL EKP+  +    +E++  A+   + LM     R  PAV  LK  + +G LG++  
Sbjct: 84  GKAVLCEKPLGVNAAEVREMVAEARSRGLFLMEAIWTRCFPAVDALKSLLAQGALGDLRV 143

Query: 147 MTAKRVGPMVTRI-------SDVGVIIDLAVHDIDVMSFLTTSRVIEVYAKARNVKHPAK 199
             A+  G  +T++          G ++DL ++ +  +S +   +  E  + A   ++   
Sbjct: 144 ARAE-FGENLTQVLRSVDWAQAGGGLLDLGIYCVQFISMVFGGQKPEKIS-AVGRRYETG 201

Query: 200 VEDYALILLSFENGANGIIETNRLTPHKTRTLNVVGTEGIAYL---DYINQELTLYNE-- 254
           V+D   +LL +  G +G   T  ++   + T +V GT+GIA L    +   EL +  E  
Sbjct: 202 VDDTVTVLLQYPGGVHGSF-TCSISSKLSNTCSVSGTKGIAQLLEPCWCPTELVVNKERK 260

Query: 255 EWIYKAKINKE------EPLKLEIEHFLECVKEGKK 284
           E+    + NK+        +  E +H  +C+++G K
Sbjct: 261 EFPLAPEENKKFNYRNGMGMSYEAQHVRDCLRKGLK 296


>dbj|BAB07562.1| (AP001520) oxidoreductase [Bacillus halodurans]
           Length = 334
           
 Score = 69.9 bits (168), Expect = 4e-11
 Identities = 76/329 (23%), Positives = 138/329 (41%), Gaps = 32/329 (9%)

Query: 1   MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADIN-FERAKEVAETFKT-RAFKDYRE 58
           +R G++G    G    ++   + +    E++ V+  N  E+A   A+     + +  Y +
Sbjct: 5   VRWGILGTA--GIAKKQLIPAIKRASNAEVVAVSSRNDMEKANCYADECDIPKRYARYED 62

Query: 59  LIKE-GVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVL 117
           L+ +  +DAV I +P  LH        E+   VL EKP A +   A+E++ A     VV 
Sbjct: 63  LLNDPDIDAVYIPLPNHLHLTWAKKAAEHGKHVLCEKPAALTAAEAKEMVDACAAHGVVF 122

Query: 118 MVGHVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTRISDV--------GVIIDLA 169
           M   + +F+P   ++K  I+ G +GE+  + +     +    +++        G + D+ 
Sbjct: 123 MEAFMYQFHPQHGEVKRLIDSGKIGEVRLIRSNFSFQLPLEANNIRLNREMGGGSLYDVG 182

Query: 170 VHDIDVMSFLTTSRVIEVYAKARNVKHPAKVEDYALI-LLSFENGANGIIETNRLTPHKT 228
            + I +  +LT    +  Y       HP    D +   +L  E G   +  T+       
Sbjct: 183 CYCIHLTRYLTGKEPVHAY--GTGYLHPELGVDTSFTGVLQMEGGVTSVF-TSSFEQPAD 239

Query: 229 RTLNVVGTEGIAYLDYI-----NQELTLYNEEWIYKAKINKEEPL-------KLEIEHFL 276
            +  VVGTEG   + Y      +Q+ T      I +    +EE L       +L++EH  
Sbjct: 240 DSYEVVGTEGTIIVPYAFRPDKHQDGT---GVIIVRTSDGREETLSVQGDQYRLQVEHVS 296

Query: 277 ECVKEGKKPLVGGEEGLHALKVAVKALES 305
           + +  G   L  GEE ++ + V    L S
Sbjct: 297 DAILNGTPLLYPGEETVNNMSVVEACLHS 325


>pir||A82502 oxidoreductase, Gfo/Idh/MocA family VCA0099 [imported] - Vibrio
           cholerae (group O1 strain N16961)
           >gi|9657485|gb|AAF96013.1| (AE004352) oxidoreductase,
           Gfo/Idh/MocA family [Vibrio cholerae]
           Length = 346
           
 Score = 69.5 bits (167), Expect = 5e-11
 Identities = 82/341 (24%), Positives = 152/341 (44%), Gaps = 36/341 (10%)

Query: 8   VGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKD--YRELIKEGVD 65
           VG +GY ++     L     +E + ++ I+  + + V E +   A+ D   R + +  VD
Sbjct: 8   VGVIGYGYSAKTFHLPFIDTLESLTLSAISSSQQQVVQEDWPQIAYFDSAQRLITESDVD 67

Query: 66  AVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMVGHVERF 125
            V I  P ++H  +    +E+   V+VEKP    IE  + +I+ A++  ++L V H  R+
Sbjct: 68  LVIITAPNNVHFPLAKLALEHGKHVIVEKPFVTQIEQGRTLIELARQQGLLLSVFHNRRW 127

Query: 126 NPAVLKLKETIERGMLGEIVTMTA--KRVGPMVTR------ISDVGVIIDLAVHDIDVMS 177
           +   L +K+ IE+G LG++    +   R  P+V +          G++ DLA H +D  +
Sbjct: 128 DGDFLTVKKLIEQGQLGDVKVFESHFDRYRPVVRQRWREQAQEGGGILFDLAPHLLD-QA 186

Query: 178 FLTTSRVIEVYAKARNVKHPAKVEDYALILLSFENGANGIIETNRLTPHKTRTLNVVGTE 237
            +       + A  R ++  A   DY  + L +       +  N  +P       V+G+ 
Sbjct: 187 LVLFGLPQSLSADCRMMRPDATTLDYFDLQLYYPQHVVR-LHANLYSPEPNVRYQVLGSL 245

Query: 238 GIAYLDY--INQELTL------YNEEW----------IYKAKINKEEPLKL-EIEHF--- 275
           G  Y+ Y    QE  L       + +W          +Y A+ N+    +L   +H+   
Sbjct: 246 G-KYVKYGLDPQEDRLKAGERPTHPQWSQEMPEQYGILYHAEGNENVITELGGYQHYFTQ 304

Query: 276 -LECVKEGKKPLVGGEEGLHALKVAVKALESSKKDEVVRVS 315
            +E ++ G    V  E  L ++++   ALESS K + + V+
Sbjct: 305 VVEAIRNGASNPVSAESALQSIQLIELALESSAKGQRLAVT 345


>dbj|BAA83486.1| (AB021929) dimeric dihydrodiol dehydrogenase [Sus scrofa]
           Length = 335
           
 Score = 68.7 bits (165), Expect = 8e-11
 Identities = 74/311 (23%), Positives = 131/311 (41%), Gaps = 38/311 (12%)

Query: 1   MRVGVVGVGKMGYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKT-RAFKDYREL 59
           +R G+V  G +      +   L    + +++ VA  +  RAKE A      +A+  Y EL
Sbjct: 3   LRWGIVSAGLISSDFTTVL-RLLPRSEHQVVAVAARDLSRAKEFARKHDIPKAYGSYEEL 61

Query: 60  IKE-GVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLM 118
            K+  V+   I      H+   +  +    +VL EKP+  +    +E++  A+   + LM
Sbjct: 62  AKDPNVEVAYIGTQHPQHKATVLLCLAAGKAVLCEKPMGVNAAEVREMVAEARSRGLFLM 121

Query: 119 VGHVERFNPAVLKLKETIERGMLGEIVTMTAK------RVGPMVTRISDVGVIIDLAVHD 172
                RF PAV  L+  + +  LG++  + A        V   V      G ++DL ++ 
Sbjct: 122 EAIWTRFFPAVEALRSVLAQETLGDLRVVQANFGKSIANVPRSVDWAQAGGSLLDLGIYC 181

Query: 173 IDVMSFLTTSRVIEVYAKARNVKHPAKVEDYALILLSFENGANGIIETNRLTPHKTRTLN 232
           +  +S +   +  E  + A   ++   V+D   +LL +  G  G   T  +T   + T++
Sbjct: 182 LQFISMVYGGQKPEKIS-AVGRRYETGVDDTVSVLLQYPGGVQGSF-TCSITSQLSNTVS 239

Query: 233 VVGTEGIAYL---DYINQELTLYNEEWIYKAKINKEEPLK----------------LEIE 273
           V GT+G+A +    +   EL +  E        +KE PL                  E +
Sbjct: 240 VSGTKGMAQILDPCWCPTELVVKGE--------HKEFPLPSAPGEEFNYTNGMGMCYEAK 291

Query: 274 HFLECVKEGKK 284
           H  EC+K+G K
Sbjct: 292 HVRECLKKGLK 302


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.317    0.135    0.366 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 102769935
Number of Sequences: 2977
Number of extensions: 3979579
Number of successful extensions: 20832
Number of sequences better than 1.0e-10: 60
Number of HSP's better than  0.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 52
Number of HSP's that attempted gapping in prelim test: 20729
Number of HSP's gapped (non-prelim): 61
length of query: 315
length of database: 189,106,746
effective HSP length: 61
effective length of query: 254
effective length of database: 152,599,039
effective search space: 38760155906
effective search space used: 38760155906
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.6 bits)
S2: 165 (68.7 bits)