BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0776 (PAB0776) DE:UDP-N-ACETYL-D-MANNOSAMINURONIC ACID
DEHYDROGENASE
(448 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||F75096 udp-n-acetyl-d-mannosaminuronic acid dehydrogenase P... 895 0.0
pir||E69211 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase -... 326 2e-88
pir||G75173 udp-n-acetyl-d-mannosaminuronic acid dehydrogenase P... 267 2e-70
pir||B71041 probable UDP-N-acetyl-D-mannosaminuronic acid dehydr... 266 3e-70
pir||F71153 probable Vi polysaccharide biosynthesis protein - Py... 257 1e-67
sp|Q57871|Y428_METJA HYPOTHETICAL PROTEIN MJ0428 >gi|2129342|pir... 252 4e-66
gb|AAC46098.1| (U81973) Cap5O [Staphylococcus aureus] 244 2e-63
gb|AAB49444.1| (U73374) Cap8O [Staphylococcus aureus] 242 8e-63
pir||H72358 lipopolysaccharide biosynthesis protein - Thermotoga... 241 1e-62
pir||B82264 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase V... 233 3e-60
gb|AAF67264.1|AF169324_2 (AF169324) BcbB [Pasteurella multocida] 231 2e-59
sp|Q45410|EPSD_BURSO NDP-N-ACETYL-D-GALACTOSAMINURONIC ACID DEHY... 229 6e-59
gb|AAF08248.1|AF170495_9 (AF170495) UDP-N-acetylglucosamine-2-ep... 220 2e-56
gb|AAF33466.1| (AF233324) 90% identity with E. coli UDP-N-acetyl... 214 2e-54
pir||T44829 probable NDP-N-acetyl-D-galactosaminuronic acid dehy... 214 2e-54
pir||A83252 probable UDP-glucose/GDP-mannose dehydrogenase WbpA ... 213 3e-54
pir||B49350 hypothetical protein 379 (nfrC 3' region) - Escheric... 212 9e-54
sp|P27829|WECC_ECOLI UDP-N-ACETYL-D-MANNOSAMINURONIC ACID DEHYDR... 210 2e-53
pir||T44509 Vi polysaccharide biosynthetic protein [imported] - ... 203 3e-51
pir||T44520 lipopolysaccharide biosynthesis protein [imported] -... 203 3e-51
sp|P39861|CAPL_STAAU CAPL PROTEIN >gi|506708|gb|AAA64651.1| (U10... 196 6e-49
gb|AAF23997.1| (AF035937) WbpO [Pseudomonas aeruginosa] 194 2e-48
pir||S30681 hypothetical protein o379 - Escherichia coli >gi|148... 192 5e-48
gi|11498204 UDP-glucose dehydrogenase (ugd-2) [Archaeoglobus ful... 190 3e-47
gb|AAA84869.1| (U34305) ORF1; Method: conceptual translation su... 186 4e-46
sp|Q04972|VIPA_SALTI VI POLYSACCHARIDE BIOSYNTHESIS PROTEIN VIPA... 185 8e-46
pir||F69727 biosynthesis of teichuronic acid (UDP-glucose 6-dehy... 183 3e-45
gb|AAD40718.1|AF048749_14 (AF048749) putative UDP-glucose-6 dehy... 182 1e-44
sp|O54068|UDG_RHIME UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDRO... 182 1e-44
pir||H75095 udp-glucose dehydrogenase (ugd) PAB0770 - Pyrococcus... 181 1e-44
pir||T46573 UDPglucose 6-dehydrogenase (EC 1.1.1.22) [validated]... 178 8e-44
pir||C82713 polysaccharide biosynthetic protein XF1183 [imported... 175 9e-43
pir||F82659 UDP-glucose dehydrogenase XF1606 [imported] - Xylell... 173 5e-42
pir||H70301 nucleotide sugar dehydrogenase - Aquifex aeolicus >g... 169 4e-41
gb|AAF23790.1|AF213822_5 (AF213822) UDP-glucose dehydrogenase [Z... 167 2e-40
gb|AAG18685.1| (AE004973) UDP-glucose dehydrogenase; Ugd [Haloba... 166 5e-40
gb|AAD56735.1|AF125164_8 (AF125164) UDP-ManNAc dehydrogenase [Ba... 165 8e-40
emb|CAC05895.1| (AL391754) putative dehydrogenase [Streptomyces ... 164 1e-39
gb|AAG26472.1|AF285774_12 (AF285774) putative UDP-glucose dehydr... 162 9e-39
pir||B83202 probable nucleotide sugar dehydrogenase PA3559 [impo... 161 2e-38
sp|O05973|UDG_RICPR UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDRO... 159 6e-38
pir||A70067 NDP-sugar dehydrogenase homolog ywqF - Bacillus subt... 158 1e-37
emb|CAB82012.1| (AL161755) putative nucleotide-sugar dehydrogena... 157 2e-37
pir||G69988 NDP-sugar dehydrogenase homolog ytcA - Bacillus subt... 157 2e-37
pir||S74698 UDP-glucose dehydrogenase - Synechocystis sp. (strai... 157 2e-37
emb|CAA72087.1| (Y11203) UDP-glucose dehydrogenase [Acetobacter ... 155 1e-36
gb|AAG19454.1| (AE005038) UDP-glucose dehydrogenase; Udg1 [Halob... 152 8e-36
emb|CAA11569.1| (AJ223832) hypothetical protein [Mycobacterium a... 149 5e-35
pir||H83393 probable nucleotide sugar dehydrogenase PA2022 [impo... 147 2e-34
gb|AAK41109.1| UDP-glucose 6-dehydrogenase (ugd) [Sulfolobus sol... 146 6e-34
gb|AAD43344.1|AF159428_1 (AF159428) putative UDP-glucose dehydro... 146 6e-34
emb|CAB57493.1| (Y18930) udp-glucose dehydrogenase [Sulfolobus s... 146 6e-34
pir||C70526 probable UDP-glucose dehydrogenase - Mycobacterium t... 143 4e-33
gi|11497917 UDP-glucose dehydrogenase (ugd-1) [Archaeoglobus ful... 136 5e-31
emb|CAB58323.1| (AL121855) UDP-glucose/GDP-mannose family dehydr... 136 7e-31
sp|O07299|ALGD_PSESH GDP-MANNOSE 6-DEHYDROGENASE (GMD) >gi|21607... 133 3e-30
gi|10956342 pXO1-95 [Bacillus anthracis] >gi|7474336|pir||G59102... 133 4e-30
gb|AAC12870.1| (AF044332) UDP-ManNAc dehydrogenase; RffD [Pectob... 125 7e-28
sp|P51585|ALGD_AZOVI GDP-MANNOSE 6-DEHYDROGENASE (GMD) >gi|10019... 124 2e-27
pir||H83203 GDP-mannose 6-dehydrogenase AlgD PA3540 [imported] -... 121 1e-26
sp|P11759|ALGD_PSEAE GDP-MANNOSE 6-DEHYDROGENASE (GMD) >gi|65967... 120 2e-26
gb|AAD44217.2|AF143772_23 (AF143772) GdhgA [Mycobacterium avium] 115 8e-25
gb|AAD20371.1| (AF125999) UDP-D-glucose-dehydrogenase gdhgA [Myc... 114 2e-24
dbj|BAB07427.1| (AP001519) nucleotide sugar dehydrogenase [Bacil... 110 4e-23
dbj|BAB11006.1| (AB009054) UDP-glucose dehydrogenase [Arabidopsi... 109 5e-23
dbj|BAA99938.1| (AP001309) UDP-glucose dehydrogenase [Arabidopsi... 109 5e-23
gb|AAF98561.1|AC013427_4 (AC013427) Strong similarity to UDP-Glu... 107 2e-22
pir||JC2525 UDP-glucose dehydrogenase (EC 1.1.99.-) - Xanthomona... 105 9e-22
gb|AAD45294.1|AF156256_2 (AF156256) putative dehydrogenase [Vibr... 105 1e-21
gb|AAC67251.2| (AF067175) UDP-glucose dehydrogenase [Pasteurella... 102 8e-21
pir||T51527 UDP-glucose dehydrogenase-like protein - Arabidopsis... 101 2e-20
sp|Q96558|UGDH_SOYBN UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDR... 101 2e-20
sp|O02373|UGDH_DROME UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDR... 100 5e-20
gb|AAC97125.1| (AF001310) UDP-glucose dehydrogenase [Drosophila ... 99 1e-19
pir||S70888 nucleotide sugar dehydrogenase homolog - Vibrio chol... 98 2e-19
sp|O33952|UDG8_ECOLI UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDR... 97 4e-19
pir||T44338 hypothetical protein wbfV [imported] - Vibrio choler... 96 6e-19
emb|CAB46919.2| (AJ242946) putative UDP-glucose dehydrogenase [S... 96 6e-19
gb|AAF04455.1|AF053973_1 (AF053973) UDP-glucose dehydrogenase [P... 96 1e-18
pir||A81290 probable UDPglucose 6-dehydrogenase (EC 1.1.1.22) Cj... 94 2e-18
sp|O86422|UDG_PSEAE UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDRO... 94 3e-18
gi|4507813 UDP-glucose dehydrogenase [Homo sapiens] >gi|11435916... 93 5e-18
sp|P12378|UGDH_BOVIN UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDR... 93 5e-18
sp|O70199|UGDH_RAT UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROG... 92 1e-17
gb|AAD50493.1|AF172324_11 (AF172324) UDP-Glc-6-dehydrogenase Ugd... 92 1e-17
pir||JE0353 uridine diphosphoglucose dehydrogenase (EC 1.-.-.-) ... 91 2e-17
pir||A54926 UDPglucose 6-dehydrogenase (EC 1.1.1.22) - bovine >g... 91 3e-17
gi|6678499 UDP-glucose dehydrogenase [Mus musculus] >gi|6136117|... 91 3e-17
pir||F82417 UDP-glucose 6-dehydrogenase VCA0780 [imported] - Vib... 91 3e-17
gb|AAF04239.1|AF093225_1 (AF093225) Vps21 [Vibrio cholerae] 90 6e-17
emb|CAB43615.1| (AJ239004) uridine diphosphate glucose dehydroge... 89 8e-17
emb|CAB05929.1| (Z83335) uridine diphosphate glucose dehydrogena... 89 1e-16
sp|Q58454|YA54_METJA HYPOTHETICAL PROTEIN MJ1054 >gi|2129344|pir... 89 1e-16
sp|Q47329|UDG5_ECOLI UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDR... 87 3e-16
sp|Q04873|UDG_SALTY UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDRO... 87 4e-16
gb|AAC45348.1| (U90519) putative UDP-glucose dehydrogenase [Esch... 84 3e-15
gb|AAD10180.1| (AF026471) Cps2K [Streptococcus pneumoniae] 83 4e-15
emb|CAA79813.1| (Z21706) ORF7 [synthetic construct] 83 4e-15
sp|P76373|UDG_ECOLI UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDRO... 83 8e-15
gi|9632145 PBCV-1 UDP-glucose dehydrogenase [Paramecium bursaria... 82 1e-14
dbj|BAA77737.1| (AB008676) UDP-glucose-6-dehydrogenase [Escheric... 82 1e-14
sp|Q04872|UDG1_ECOLI UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDR... 82 2e-14
gb|AAG35229.1| (AF176369) UDP-glucose-6-dehydrogenase [Escherich... 81 2e-14
sp|Q07172|UDG_STRPY UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDRO... 80 4e-14
sp|P37791|UDG_SHIFL UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDRO... 77 3e-13
pdb|1DLJ|A Chain A, The First Structure Of Udp-Glucose Dehydroge... 76 6e-13
gb|AAC43311.1| (U15171) UDP-glucose dehydrogenase [Streptococcus... 73 5e-12
sp|Q57346|UDG_STRPN UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDRO... 73 9e-12
emb|CAA78147.1| (Z12159) uridine diphosphate glucose dehydrogena... 69 7e-11
>pir||F75096 udp-n-acetyl-d-mannosaminuronic acid dehydrogenase PAB0776 -
Pyrococcus abyssi (strain Orsay)
>gi|5458587|emb|CAB50075.1| (AJ248286)
UDP-N-ACETYL-D-MANNOSAMINURONIC ACID DEHYDROGENASE
[Pyrococcus abyssi]
Length = 448
Score = 895 bits (2288), Expect = 0.0
Identities = 448/448 (100%), Positives = 448/448 (100%)
Query: 1 MVKLLGMSREDVREAIKNGDVTIAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVN 60
MVKLLGMSREDVREAIKNGDVTIAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVN
Sbjct: 1 MVKLLGMSREDVREAIKNGDVTIAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVN 60
Query: 61 NGENHIKEEPGLDELVKKNVEAGRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESV 120
NGENHIKEEPGLDELVKKNVEAGRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESV
Sbjct: 61 NGENHIKEEPGLDELVKKNVEAGRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESV 120
Query: 121 YDVAEKISKGLEKGDIVITEATMPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAI 180
YDVAEKISKGLEKGDIVITEATMPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAI
Sbjct: 121 YDVAEKISKGLEKGDIVITEATMPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAI 180
Query: 181 RDITGQYPKIVGASDERTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIAL 240
RDITGQYPKIVGASDERTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIAL
Sbjct: 181 RDITGQYPKIVGASDERTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIAL 240
Query: 241 ANELALWCEEHGLDAIEIFNAANTQPYCHLHMPGAGVGGHCIPIYPWFVINLAKKTNVRL 300
ANELALWCEEHGLDAIEIFNAANTQPYCHLHMPGAGVGGHCIPIYPWFVINLAKKTNVRL
Sbjct: 241 ANELALWCEEHGLDAIEIFNAANTQPYCHLHMPGAGVGGHCIPIYPWFVINLAKKTNVRL 300
Query: 301 IRTAREINDSMPRHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRE 360
IRTAREINDSMPRHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRE
Sbjct: 301 IRTAREINDSMPRHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRE 360
Query: 361 LKEWGAEVYAYDPLCTREDAERFGAKWKEDFKDVDAIVIVTDHREFKTLDLKEIAAEVRT 420
LKEWGAEVYAYDPLCTREDAERFGAKWKEDFKDVDAIVIVTDHREFKTLDLKEIAAEVRT
Sbjct: 361 LKEWGAEVYAYDPLCTREDAERFGAKWKEDFKDVDAIVIVTDHREFKTLDLKEIAAEVRT 420
Query: 421 KVIVDGRNVIHPEEAKKLGFIYKGVGRV 448
KVIVDGRNVIHPEEAKKLGFIYKGVGRV
Sbjct: 421 KVIVDGRNVIHPEEAKKLGFIYKGVGRV 448
>pir||E69211 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase -
Methanobacterium thermoautotrophicum (strain Delta H)
>gi|2621926|gb|AAB85334.1| (AE000860)
UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase
[Methanobacterium thermoautotrophicum]
Length = 431
Score = 326 bits (828), Expect = 2e-88
Identities = 184/435 (42%), Positives = 262/435 (59%), Gaps = 14/435 (3%)
Query: 20 DVTIAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKN 79
D IAV+GLG +GLP AA+FA G KV GVDIN V VN G + + E PGLDELV +
Sbjct: 3 DQRIAVFGLGHIGLPTAALFARAGFKVTGVDINPETVEKVNIGRSPVLE-PGLDELVAEV 61
Query: 80 VEAGRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVIT 139
V G L AT DG AA +++VMII+VPT + L +V AE IS+GL+KGD+VI
Sbjct: 62 VGTGNLGATMDGERAAAESEVMIIVVPTPVNSENTSDLSAVISAAETISRGLKKGDLVIV 121
Query: 140 EATMPPGTTESLI-PILEKSGLKLG-DFGLAHAPERTMTGTAIRDITGQYPKIVGASDER 197
E+T+PPG ++++ PILEK+GLK+ DFGLA+ PER + + ++ +++G +D
Sbjct: 122 ESTVPPGACQNVVLPILEKTGLKVSEDFGLAYTPERALPNNTLHEMQNN-ARVIGGADPE 180
Query: 198 TLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIE 257
+ +Y I VI + + AE VK+ E YRD NIALANELA+ CE G+DAI
Sbjct: 181 SARRAAALYRRITSGEVIVVDDLMTAEMVKLMENTYRDTNIALANELAVICEALGIDAIN 240
Query: 258 IFNAANTQPYCHLHMPGAGVGGHCIPIYPWFVINLAKKTNV--RLIRTAREINDSMPRHV 315
AAN P ++H PG GVGGHC+ I P+F++ +A++ V RLIRTARE+N+SMP HV
Sbjct: 241 AIEAANHHPRVNIHTPGPGVGGHCLSIDPYFIVEMAERKGVPARLIRTAREVNESMPLHV 300
Query: 316 VELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYAYDPLC 375
+E+ L GK +KGS + +LG+ ++G V + ++P ++ L GA V DP
Sbjct: 301 LEIVRETLESRGKTLKGSNVGILGVAYKGDVADARETPTRPLVAALLSEGARVLVNDPHV 360
Query: 376 TREDAERFGAK--WKEDFKDVDAIVIVTDHREFKTLDLKEIAAE-VRTKVIVDGRNVIHP 432
+ E G + E+ + D +V++TDH E+ EI E + + + R V+ P
Sbjct: 361 SPEIIRGMGVEPVSLEEALNSDCVVLMTDHTEY-----LEITPEMIPGGIFICTRPVMDP 415
Query: 433 EEAKKLGFIYKGVGR 447
E + G ++GVGR
Sbjct: 416 ERFRTRGITFRGVGR 430
>pir||G75173 udp-n-acetyl-d-mannosaminuronic acid dehydrogenase PAB0378 -
Pyrococcus abyssi (strain Orsay)
>gi|5457980|emb|CAB49470.1| (AJ248284)
UDP-N-ACETYL-D-MANNOSAMINURONIC ACID DEHYDROGENASE
[Pyrococcus abyssi]
Length = 418
Score = 267 bits (676), Expect = 2e-70
Identities = 169/427 (39%), Positives = 248/427 (57%), Gaps = 16/427 (3%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
IAV GLG +GLP A +FA +G VIG DI VV VN G HI E P + E +++ V
Sbjct: 3 IAVIGLGYIGLPTAIMFASSGHDVIGYDIRRDVVEKVNRGIAHIVE-PEIGERLREVVSK 61
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITEAT 142
G+L+AT+D K AD II V T + G L + + I+K +EK +V+ E+T
Sbjct: 62 GKLRATSD-YNDLKGADAFIICVQTPLSN-GVPDLTYLESAIKTIAKVIEKEALVVIEST 119
Query: 143 MPPGTTESLIPILEK-SGLKLG-DFGLAHAPERTMTGTAIRDITGQYPKIVGASDERTLE 200
+PPGTTE + +LE+ +GLK G DF +AHAPER M G +++ +I+G E+
Sbjct: 120 VPPGTTERMAKLLEELTGLKEGEDFYVAHAPERVMPGRIFKELVYN-SRIIGGVSEKASI 178
Query: 201 AVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIEIFN 260
+Y + KG I +++ AE VK+ E +RDVNIALANE A ++G++ E
Sbjct: 179 LAEKLYRSFV-KGRIFLTTATTAEMVKLMENTFRDVNIALANEFAFLAHKYGVNVYEAIE 237
Query: 261 AANTQPYCHLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREINDSMPRHVVELTV 320
ANT P +H PG GVGGHC+P P+ ++ + ++ LIR AR+IN+SMPR +L
Sbjct: 238 LANTHPRVKIHRPGIGVGGHCLPKDPYLLLANVDE-DLGLIRKARKINESMPRFAAKLLF 296
Query: 321 RALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYAYDPLCTREDA 380
AL +A + +LVLGL ++G + SPA++ I+ +++ EV YDP
Sbjct: 297 EALGEANVDPGDAVVLVLGLAYKGDTDDVRNSPALEFIKIIEKDVKEVRTYDPYVNGTH- 355
Query: 381 ERFGAKWKEDFKDVDAIVIVTDHREFKTLDLKEIAAEVRTKVIVDGRNVIHPEEAKKLGF 440
+E K VDAI+I TDH F+ ++ ++ +R K+I+DGRN++ +E K GF
Sbjct: 356 ----TILEEAVKGVDAIIIATDHSMFREIEWDKLGNLMRNKIIIDGRNLV--KEPPK-GF 408
Query: 441 IYKGVGR 447
I+KG+GR
Sbjct: 409 IFKGIGR 415
>pir||B71041 probable UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase -
Pyrococcus horikoshii >gi|3258047|dbj|BAA30730.1|
(AP000006) 418aa long hypothetical
UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase
[Pyrococcus horikoshii]
Length = 418
Score = 266 bits (674), Expect = 3e-70
Identities = 166/431 (38%), Positives = 244/431 (56%), Gaps = 24/431 (5%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
IAV GLG +GLP A +FA +G V+G DI V+ +N+G HI E P +D +K+ +
Sbjct: 3 IAVLGLGYIGLPTAIMFASSGYDVVGYDIRSEVIKKINSGVAHIIE-PEIDRRLKEVLSL 61
Query: 83 GRLKATTDGILAAKKADVMIILV--PTLADDRGNLKLESVYDVAEKISKGLEKGDIVITE 140
G+LK T D + K ++V II V P DD LE ++ +++G +VI E
Sbjct: 62 GKLKVT-DRVEDLKGSNVFIICVQTPLSGDDPDLSYLERAIRTVAEV---MDRGALVIIE 117
Query: 141 ATMPPGTTESLIPILEK-SGLKLG-DFGLAHAPERTMTGTAIRDITGQYPKIVGASDERT 198
+T+PPGTTE + +LE +GL+ G DF +AHAPER M G +++ +I+G E+
Sbjct: 118 STIPPGTTEKMARLLENLTGLREGVDFYVAHAPERVMPGRIFKELVYN-SRIIGGVSEKA 176
Query: 199 LEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIEI 258
+Y + KG I +++ AE VK+ E +RDVNIALANE AL ++G++ E
Sbjct: 177 ANLAEKLYRSFV-KGRIFLTNATTAEMVKLMENTFRDVNIALANEFALLAHQYGVNVYEA 235
Query: 259 FNAANTQPYCHLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREINDSMPRHVVEL 318
ANT P +H PG GVGGHC+P P+ +++ AK+ + LIR AR IN+ MP L
Sbjct: 236 IELANTHPRVKIHTPGIGVGGHCLPKDPYLLLSNAKE-DFGLIRIARRINERMPAFAAGL 294
Query: 319 TVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYAYDPLC--T 376
AL A + I VLGL ++GG + SPA+ + ++ EV YDP T
Sbjct: 295 LFEALEKANIKPSEAIIAVLGLAYKGGTDDTRNSPALKFVEIIRNSVKEVRTYDPYVRGT 354
Query: 377 REDAERFGAKWKEDFKDVDAIVIVTDHREFKTLDLKEIAAEVRTKVIVDGRNVIHPEEAK 436
+ E+ + DAIVI TDH EFK+++ + I +R K+I+DGRN+I +
Sbjct: 355 HDSLEKV-------VEGADAIVIATDHPEFKSVNWESIGKSMRHKIIIDGRNII---KEP 404
Query: 437 KLGFIYKGVGR 447
+GFI++G+GR
Sbjct: 405 PVGFIFRGIGR 415
>pir||F71153 probable Vi polysaccharide biosynthesis protein - Pyrococcus
horikoshii >gi|3256832|dbj|BAA29515.1| (AP000002) 455aa
long hypothetical Vi polysaccharide biosynthesis protein
[Pyrococcus horikoshii]
Length = 455
Score = 257 bits (651), Expect = 1e-67
Identities = 175/456 (38%), Positives = 252/456 (54%), Gaps = 30/456 (6%)
Query: 10 EDVREAIKNGDVTIAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEE 69
E +++ IK+ I + GLG +GLPLA F+ VIG DIN + ++S+ +++I
Sbjct: 7 ESLKKKIKDRSAIIGIVGLGYVGLPLAVAFSKK-FNVIGYDINTKKIDSLKKRKSYI--- 62
Query: 70 PGLDELVKKNVEAGRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISK 129
+++ + RL+ T D KK D +II VPT + L V D A + +
Sbjct: 63 ---EDVRDDEINLNRLQPTNDPE-DLKKCDFIIITVPTPLREDKTPDLSYVKDAARTVGR 118
Query: 130 GLEKGDIVITEATMPPGTTES-LIPILEK-SGLK-LGDFGLAHAPERTMTGTAIRDITGQ 186
L +G VI E+T PGTTE LIPILE+ SGLK + DFG+A++PER G I
Sbjct: 119 ILRRGQFVILESTTYPGTTEEVLIPILEEESGLKVIEDFGVAYSPERIDPGNKRYKIENT 178
Query: 187 YPKIVGASDERTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELAL 246
PK+VG E +Y ++ K ++P+ K AEAVK+ E ++R+VNIAL NELAL
Sbjct: 179 -PKVVGGLTPEFTELASMLYGSVIEK-IVPVKDCKTAEAVKMLENVFRNVNIALVNELAL 236
Query: 247 WCEEHGLDAIEIFNAANTQPYCHLHM-PGAGVGGHCIPIYPWFVINLAKKTNV--RLIRT 303
E+ G+D E+ AA T+PY + PG GVGGHCIP+ P+++ AK+ + R I T
Sbjct: 237 IFEKMGIDIWEVIEAAKTKPYGFMAFYPGPGVGGHCIPVDPYYLSYRAKQFGIIPRFIET 296
Query: 304 AREINDSMPRHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKE 363
A EIN+ MP H V L L G+ ++G+K+ VLGL ++ + + +SPAI +I EL E
Sbjct: 297 AGEINNYMPVHTVNLAETGLRKIGRKIRGAKVAVLGLAYKADISDTRESPAIKIIEELIE 356
Query: 364 WGAEVYAYDPLCTREDAERFGA-KWKEDFKDV----DAIVIVTDHREFKTL--DLKEIAA 416
GA+V YDP + +FG + E +D+ D ++ VTDH FK ++ +I
Sbjct: 357 RGAQVKVYDPY-VKSVRTKFGTFRVTETLEDILKWSDCVIFVTDHSLFKEKMEEILKIFG 415
Query: 417 EVRT-KVIVDGRNVIHPEEA-----KKLGFIYKGVG 446
E T KVIVD RN+ KL +I G G
Sbjct: 416 ETSTKKVIVDSRNIFEKVSPSTFFNSKLEYIKLGFG 451
>sp|Q57871|Y428_METJA HYPOTHETICAL PROTEIN MJ0428 >gi|2129342|pir||D64353
UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase
homolog - Methanococcus jannaschii
>gi|1591131|gb|AAB98413.1| (U67494)
UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase
[Methanococcus jannaschii]
Length = 427
Score = 252 bits (638), Expect = 4e-66
Identities = 170/440 (38%), Positives = 242/440 (54%), Gaps = 45/440 (10%)
Query: 17 KNG-DVTIAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDEL 75
KNG I V GLG +GLP A++ A G VIGVDINE+ V + E+ L L
Sbjct: 6 KNGIGKRICVIGLGYIGLPTASMLAIQGFDVIGVDINEKRVKEIKELSFKTTEKD-LMTL 64
Query: 76 VKKNVEAGRLKATTDGILAAKKADVMIILVPT-LADDRGNLKLESVY--DVAEKISKGLE 132
VK + +G LK T +KADV II VPT + G K + Y E I LE
Sbjct: 65 VKGAINSGNLKVQTK----PEKADVFIICVPTPCIECDGEKKCDLTYLNKAIESIKPYLE 120
Query: 133 KGDIVITEATMPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVG 192
G+++I E+T+PPGTT+ + L K +AH PER + G+ ++++ + +++G
Sbjct: 121 NGNLIIIESTIPPGTTDDIYKKLSKDK----KIYVAHCPERVLPGSILKELV-ENDRVIG 175
Query: 193 ASDERTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHG 252
DE++ E IYET G I ++ K AE VK+ E YRDVNIALANE A EE G
Sbjct: 176 GVDEKSAEMAKEIYETFVT-GKIYLTDAKTAEMVKLMENTYRDVNIALANEFAKIAEEIG 234
Query: 253 LDAIEIFNAANTQPYCHLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREINDSMP 312
++ E AN P ++ PG GVGGHCI I PWF++ K N +LIRTARE+NDSMP
Sbjct: 235 INVWEAIELANKHPRVNILKPGPGVGGHCISIDPWFIVE--KSKNAKLIRTARELNDSMP 292
Query: 313 RHVVELTVRAL-NDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYAY 371
VVE + + D G K+ + G+T++G V + +SPA V+ +L + G EV Y
Sbjct: 293 LFVVEKIKKIIKKDIG------KVAIFGVTYKGNVDDTRESPAEKVVSKLIDEGFEVKCY 346
Query: 372 D--------PLCTREDAERFGAKWKEDFKDVDAIVIVTDHREFKTL---DLKEIAAEVRT 420
D PL + ++A + D IVI+ +H E+K D+K IA++V+
Sbjct: 347 DKYARDFIYPLNSLDEA----------VEGADIIVILAEHDEYKNFDKEDIKNIASKVKN 396
Query: 421 KVIVDGRNVIHPEEAKKLGF 440
K+I+D +N+++ E +K GF
Sbjct: 397 KIILDTKNILNRELWEKEGF 416
>gb|AAC46098.1| (U81973) Cap5O [Staphylococcus aureus]
Length = 420
Score = 244 bits (616), Expect = 2e-63
Identities = 148/413 (35%), Positives = 234/413 (55%), Gaps = 21/413 (5%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
+ V GLG +GLP + +FA +G V+GVDIN++ ++ + NG+ I EEPGL E+ ++ + +
Sbjct: 3 LTVVGLGYIGLPTSIMFAKHGVDVLGVDINQQTIDKLQNGQISI-EEPGLQEVYEEVLSS 61
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRG--NLKLESVYDVAEKISKGLEKGDIVITE 140
G+LK +T + +DV II VPT +D + + V + I L+KG+ +I E
Sbjct: 62 GKLKVST----TPEASDVFIIAVPTPNNDDQYRSCDISLVMRALDSILPFLKKGNTIIVE 117
Query: 141 ATMPPGTTESLI-PILEKSGLKLG-DFGLAHAPERTMTGTAIRDITGQYPKIVGASDERT 198
+T+ P T + + P++E G +G D L H PER + G + ++ +I+G +
Sbjct: 118 STIAPKTMDDFVKPVIENLGFTIGEDIYLVHCPERVLPGKILEELVHNN-RIIGGVTKAC 176
Query: 199 LEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIEI 258
+EA +Y T + +I + + AE K+ E YRDVNIALANEL C ++ +++
Sbjct: 177 IEAGKRVYRTFVQGEMIETDA-RTAEMSKLMENTYRDVNIALANELTKICNNLNINVLDV 235
Query: 259 FNAANTQPYCHLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREINDSMPRHVVEL 318
AN P ++H PG GVGGHC+ + P+F+I N +LI+T REIN+SMP +VV+
Sbjct: 236 IEMANKHPRVNIHQPGPGVGGHCLAVDPYFII-AKDPENAKLIQTGREINNSMPAYVVDT 294
Query: 319 TVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIREL-KEWGAEVYAYDPLCTR 377
T + + K + G+K+ V GLT++G V + +SPA D+ L +E EV AYDP
Sbjct: 295 TKQII----KALSGNKVTVFGLTYKGDVDDIRESPAFDIYELLNQEPDIEVCAYDPHVEL 350
Query: 378 EDAERFGAKWKEDFKDVDAIVIVTDHREFKTLDLKEIAAEVRTKVIVDGRNVI 430
+ E KD ++I++DH EFK L +++ KVI D +NV+
Sbjct: 351 DFVEH---DMSHAVKDASLVLILSDHSEFKNLSDSHF-DKMKHKVIFDTKNVV 399
>gb|AAB49444.1| (U73374) Cap8O [Staphylococcus aureus]
Length = 420
Score = 242 bits (610), Expect = 8e-63
Identities = 148/413 (35%), Positives = 233/413 (55%), Gaps = 21/413 (5%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
+ V GLG +GLP + +FA +G V+GVDIN++ ++ + +G+ I EEPGL E+ ++ + +
Sbjct: 3 LTVVGLGYIGLPTSIMFAKHGVDVLGVDINQQTIDKLQSGQISI-EEPGLQEVYEEVLSS 61
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRG--NLKLESVYDVAEKISKGLEKGDIVITE 140
G+LK +T + +DV II VPT +D + + V + I LEKG+ +I E
Sbjct: 62 GKLKVST----TPEASDVFIIAVPTPNNDDQYRSCDISLVMRALDSILPFLEKGNTIIVE 117
Query: 141 ATMPPGTTESLI-PILEKSGLKLG-DFGLAHAPERTMTGTAIRDITGQYPKIVGASDERT 198
+T+ P T + + P++E G +G D L H PER + G + ++ +I+G +
Sbjct: 118 STIAPKTMDDFVKPVIENLGFTIGEDIYLVHCPERVLPGKILEELVHNN-RIIGGVTKAC 176
Query: 199 LEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIEI 258
+EA +Y T + +I + + AE K+ E YRDVNIALANEL C ++ + +
Sbjct: 177 IEAGKYVYRTFVQGEMIETDA-RTAEMSKLMENTYRDVNIALANELTKICNNLNINVLVV 235
Query: 259 FNAANTQPYCHLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREINDSMPRHVVEL 318
AN P ++H PG GVGGHC+ + P+F+I N +LI+T REIN+SMP +VV+
Sbjct: 236 IEMANKHPRVNIHQPGPGVGGHCLAVDPYFII-AKDPENAKLIQTGREINNSMPAYVVDT 294
Query: 319 TVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIREL-KEWGAEVYAYDPLCTR 377
T + + K + G+K+ V GLT++G V + +SPA D+ L +E EV AYDP
Sbjct: 295 TKQII----KALSGNKVTVFGLTYKGDVDDIRESPAFDIYELLNQEPDIEVCAYDPHVEL 350
Query: 378 EDAERFGAKWKEDFKDVDAIVIVTDHREFKTLDLKEIAAEVRTKVIVDGRNVI 430
+ E KD ++I++DH EFK L +++ KVI D +NV+
Sbjct: 351 DFVEH---DMSHAVKDASLVLILSDHSEFKNLSDSHF-DKMKHKVIFDTKNVV 399
>pir||H72358 lipopolysaccharide biosynthesis protein - Thermotoga maritima
(strain MSB8) >gi|4981101|gb|AAD35668.1|AE001733_5
(AE001733) lipopolysaccharide biosynthesis protein
[Thermotoga maritima]
Length = 434
Score = 241 bits (609), Expect = 1e-62
Identities = 164/436 (37%), Positives = 243/436 (55%), Gaps = 27/436 (6%)
Query: 12 VREAIKNGDVTIAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPG 71
++E + + + V GLG +GLPLA A G +V+G DI ++ V+ VN GEN+I +
Sbjct: 2 LKEKLLSKTALLGVIGLGYVGLPLAVEKAKAGYRVLGFDIQKKRVDMVNRGENYIGDV-- 59
Query: 72 LDELVKKNVEAGRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGL 131
+DE +K VE G ++ATTD K DV+ I VPT L V + A++I+K L
Sbjct: 60 VDEDLKDLVEKGMIRATTD-FSEMKNCDVVTICVPTPLGKYKEPDLTYVINTAKEIAKYL 118
Query: 132 EKGDIVITEATMPPGTTESLI-PILEKSGLKLG-DFGLAHAPERTMTGTAIRDITGQYPK 189
+ +V+ E+T PGTTE ++ PILE +GLK+G DF LA +PER G I T PK
Sbjct: 119 HREMLVVLESTTYPGTTEEVVLPILESTGLKVGKDFYLAFSPERVDPGNKIYK-TKNTPK 177
Query: 190 IVGASDERTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCE 249
+VG E+ E +YE + V +SS +AAE KV E +R VNI+L NE+A+
Sbjct: 178 VVGGVTEKCTELAKILYENVLEAPVHTVSSPRAAEMAKVLENTFRLVNISLINEVAIVAR 237
Query: 250 EHGLDAIEIFNAANTQPYCHLHM-PGAGVGGHCIPIYPWFVINLAKKTNVRL--IRTARE 306
G++ E+ +AA T+P+ + PG G GGHCIPI P+++ AK+ +VRL + A E
Sbjct: 238 RMGINIWEVIDAAATKPFGFMPFYPGPGAGGHCIPIDPFYLAYKAKEYDVRLDLVEMAGE 297
Query: 307 INDSMPRHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGA 366
IND MP +VV LN+ KP+ GSK+L+LG+ ++G + + +SPA+ V L++ A
Sbjct: 298 INDFMPEYVVMRVQDILNERKKPLNGSKVLLLGVAYKGDIDDTRESPALKVWDHLEKKKA 357
Query: 367 EVYAYDPL---CTREDAERFGAKWKEDF-KDVDAIVIVTDHRE--------------FKT 408
V +DP R D + E++ K VD +VI T H+ F T
Sbjct: 358 VVEFFDPYVPEVKRGDRIHRRVELTEEYLKGVDIVVITTAHKNGVDYDFVVKNAPVVFDT 417
Query: 409 LDLKEIAAEVRTKVIV 424
++ + E R K+I+
Sbjct: 418 KNITKDVKENRDKIIL 433
>pir||B82264 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase VC0918
[imported] - Vibrio cholerae (group O1 strain N16961)
>gi|9655375|gb|AAF94080.1| (AE004175)
UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase
[Vibrio cholerae]
Length = 413
Score = 233 bits (588), Expect = 3e-60
Identities = 148/426 (34%), Positives = 230/426 (53%), Gaps = 36/426 (8%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
++V GLG +GLP AAV A G V+GVD+N V+++N GE HI E P LD +V+ V
Sbjct: 5 VSVIGLGYIGLPTAAVLASRGLDVVGVDVNAHAVDTINKGEIHIVE-PDLDIVVRSAVMT 63
Query: 83 GRLKATTDGILAAKKADVMIILVPT-LADDRGNLKLESVYDVAEKISKGLEKGDIVITEA 141
G+LKAT L A+ AD ++ VPT D L + A+ I+ L KG++V+ E+
Sbjct: 64 GKLKAT----LTAEPADAFLVAVPTPFKGDNHEPDLSYIEAAAKTIAPVLAKGNLVVLES 119
Query: 142 TMPPGTTESLIPILEKSGLKL---------GDFGLAHAPERTMTGTAIRDITGQYPKIVG 192
T P GTTE L L ++ L D +A+ PER + G ++++ +++G
Sbjct: 120 TSPVGTTEKLAQWLAEARPDLTFPQQKGIAADVKIAYCPERVLPGYVLQELVSN-DRVIG 178
Query: 193 ASDERTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHG 252
+ E + +Y+T KG +++ + AE K+ E +RDVNIA ANEL+L C +
Sbjct: 179 GVSKACSEKAVALYKTFV-KGECIVTNARTAEMAKLTENSFRDVNIAFANELSLVCNKLK 237
Query: 253 LDAIEIFNAANTQPYCHLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREINDSMP 312
++ E+ AN P + PG GVGGHCI + PWF++N + +LIRTARE+ND P
Sbjct: 238 INVWELIRLANRHPRVSILNPGPGVGGHCIAVDPWFIVN-SCPDEAQLIRTAREVNDGKP 296
Query: 313 RHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWG-AEVYAY 371
VV+ +A + KP+ I LGL F+ + + +SPA+D+ + L E ++ A
Sbjct: 297 HWVVDQVKQAADQFKKPI----IACLGLAFKADIDDLRESPALDITKHLAESKVGQLLAV 352
Query: 372 DPLCT-------REDAERFGAKWKEDFKDVDAIVIVTDHREFKTLDLKEIAAEVRTKVIV 424
+P T ++ E + + ++ +V++ DH+EFK D E A KV++
Sbjct: 353 EPNITELPSKLAKQGIELVSLERALELANI--VVVLVDHKEFKAADKTEFA----KKVVI 406
Query: 425 DGRNVI 430
D R V+
Sbjct: 407 DTRGVV 412
>gb|AAF67264.1|AF169324_2 (AF169324) BcbB [Pasteurella multocida]
Length = 422
Score = 231 bits (582), Expect = 2e-59
Identities = 145/434 (33%), Positives = 239/434 (54%), Gaps = 42/434 (9%)
Query: 22 TIAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVE 81
TI+V GLG +GLP AAVFA + KVIG+DINE VN++N G+ HI E L+++V++ V
Sbjct: 6 TISVIGLGYIGLPTAAVFAQHHVKVIGIDINEHAVNTINQGKIHIVESD-LEQVVQQCVN 64
Query: 82 AGRLKATTDGILAAKKADVMIILVPT-LADDRGNLKLESVYDVAEKISKGLEKGDIVITE 140
G LKA+ L + AD +I VPT + L + + IS L+KGD+++ E
Sbjct: 65 KGDLKAS----LTPEPADAFLIAVPTPFKGNNYEPDLSYIKSACKMISSVLKKGDLIVLE 120
Query: 141 ATMPPGTTESL----------IPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKI 190
+T P GTTE + + ++ G +L D +AH PER + G +R++ + +I
Sbjct: 121 STSPVGTTEKMAIWLSEFRHDLTFPQQLG-ELSDIRIAHCPERVLPGHVMRELI-ENDRI 178
Query: 191 VGASDERTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEE 250
+G + + + +Y+T KG +++ + AE K+ E +RDVNIA ANEL++ C++
Sbjct: 179 IGGMTPKCSQMAVDLYKTFV-KGDCIVTNSRTAEMCKLTENAFRDVNIAFANELSIICDK 237
Query: 251 HGLDAIEIFNAANTQPYCHLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREINDS 310
G++ E+ N AN P ++ PG GVGGHCI + PWF++N + +LI TAR +NDS
Sbjct: 238 LGINVWELINLANRHPRVNILQPGCGVGGHCIAVDPWFIVNKTPEL-AKLIHTARLVNDS 296
Query: 311 MPRHVVELTVRALNDA-----GKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIREL-KEW 364
P V+ A+ +A K ++ KI LGL F+ + + +SPA+ + ++L ++
Sbjct: 297 KPEWVINQVNNAVIEALQKNPNKTLQDIKIACLGLAFKPDIDDLRESPALKITKQLAAKY 356
Query: 365 GAEVYAYDP--------LCTREDAERFGAKWKEDFKDVDAIVIVTDHREFKTLDLKEIAA 416
++ A +P L T+ + ++ + D +V++ DH+EFK + + A
Sbjct: 357 PNQITAVEPNIEALPEQLITQNIKH---SSLQQALETCDVLVVLVDHKEFKEIQTTSVNA 413
Query: 417 EVRTKVIVDGRNVI 430
IVD + ++
Sbjct: 414 -----TIVDTKGIL 422
>sp|Q45410|EPSD_BURSO NDP-N-ACETYL-D-GALACTOSAMINURONIC ACID DEHYDROGENASE
>gi|7449841|pir||S77638 probable
UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase (EC
1.1.1.-) - Pseudomonas solanacearum
>gi|600868|gb|AAA91627.1| (U17898) EpsD [Ralstonia
solanacearum]
Length = 423
Score = 229 bits (577), Expect = 6e-59
Identities = 144/423 (34%), Positives = 231/423 (54%), Gaps = 33/423 (7%)
Query: 22 TIAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVE 81
TI+V GLG +GLP A V A ++IGVDIN+ V+++N HI E P LD LV+ V
Sbjct: 11 TISVVGLGYIGLPTATVLASRQRELIGVDINQHAVDTINQARIHIVE-PDLDMLVRAAVS 69
Query: 82 AGRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITEA 141
G L+ATT+ + AD +I VPT + L + A+ I+ L++GD+V+ E+
Sbjct: 70 QGYLRATTE----PEPADAFLIAVPTPFLEDKQPDLTYIEAAAKAIAPVLKRGDLVVLES 125
Query: 142 TMPPGTTESLIPILEKSGLKLG---------DFGLAHAPERTMTGTAIRDITGQYPKIVG 192
T P G TE L L + L D +AH PER + G +R++ + +I+G
Sbjct: 126 TSPVGATEQLSAWLSEQRSDLSFPHQLGEESDIRVAHCPERVLPGHVLRELV-ENDRIIG 184
Query: 193 ASDERTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHG 252
R +A +YE R I ++ + AE K+ E +RDVNIA ANEL++ C+E G
Sbjct: 185 GMTPRCSQAAQRLYELFVRGRCI-VTDARTAEMCKLTENAFRDVNIAFANELSMICDEIG 243
Query: 253 LDAIEIFNAANTQPYCHLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREINDSMP 312
++ E+ + AN P ++ PG GVGGHCI + PWF+++ A + + RLIRTARE+ND+ P
Sbjct: 244 VNVWELISVANRHPRVNILQPGPGVGGHCIAVDPWFIVDAAPE-SARLIRTAREVNDAKP 302
Query: 313 RHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIREL-KEWGAEVYAY 371
+V++ + A + K I GL+F+ + + +SPAI+++R + ++ V
Sbjct: 303 HYVLD----RVKQAARRFKEPVIACFGLSFKANIDDLRESPAIEIVRTMVQQQLGTVLVV 358
Query: 372 DP-----LCTREDAERFGAKWKEDFKDVDAIVIVTDHREFKTLDLKEIAAEVRTKVIVDG 426
+P + E E A + D +V++ DH++F+ LD + +++V++D
Sbjct: 359 EPHIKVLPASLEGVELLNA--EPALSRADIVVLLVDHQKFRKLDTDRL----QSRVVIDT 412
Query: 427 RNV 429
R +
Sbjct: 413 RGM 415
>gb|AAF08248.1|AF170495_9 (AF170495) UDP-N-acetylglucosamine-2-epimerase [Pasteurella
haemolytica]
Length = 423
Score = 220 bits (556), Expect = 2e-56
Identities = 142/407 (34%), Positives = 217/407 (52%), Gaps = 30/407 (7%)
Query: 22 TIAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVE 81
TI+V GLG +GLP A VFA +G VIGVD+N+ V+ +N G+ HI E P LD V + V
Sbjct: 6 TISVVGLGYIGLPTATVFAQHGLNVIGVDVNQHAVDHINQGKIHIVE-PDLDVAVHQCVS 64
Query: 82 AGRLKATTDGILAAKKADVMIILVPTLADDRG-NLKLESVYDVAEKISKGLEKGDIVITE 140
+G+LKAT L + A+ +I VPT + L + + I+ LEKG++VI E
Sbjct: 65 SGKLKAT----LTPEPAEAFLIAVPTPFKGQDYEPDLSYIQAACKAIAPVLEKGNLVILE 120
Query: 141 ATMPPGTTESLIPILEKSGLKLG---------DFGLAHAPERTMTGTAIRDITGQYPKIV 191
+T P G TE + L + +L D +AH PER + G + ++ + +IV
Sbjct: 121 STSPVGATEQMAEWLAEYRPELSFPQQAGEDSDIRIAHCPERVLPGQVMHELI-ENDRIV 179
Query: 192 GASDERTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEH 251
G + + +Y+T KG +++ + AE K+ E +RDVNIA ANEL++ C+
Sbjct: 180 GGMTNKCSVQAVNLYKTFV-KGDCIVTNARTAEMCKLTENSFRDVNIAFANELSIICDRL 238
Query: 252 GLDAIEIFNAANTQPYCHLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREINDSM 311
++ E+ AN P ++ PG GVGGHCI + PWF++N ++IRT RE+ND
Sbjct: 239 DINVWELIALANRHPRVNILQPGCGVGGHCIAVDPWFIVNKTPDL-AKIIRTGREVNDHK 297
Query: 312 PRHVV----ELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKE-WGA 366
P V+ E + AL GK + KI LGL F+ + + +SPA+ + +L E +
Sbjct: 298 PEWVISKMNEAVIYALQKTGKSIDQIKIACLGLAFKPDIDDLRESPALKITEKLAEKYPN 357
Query: 367 EVYAYDPLCTREDAERFGAK------WKEDFKDVDAIVIVTDHREFK 407
+V+A +P E ++ K E + D +V++ DH EFK
Sbjct: 358 QVFAVEP-NVEELPKKLANKNISLISVDEALEVADVVVVLVDHSEFK 403
>gb|AAF33466.1| (AF233324) 90% identity with E. coli
UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase
(WECC) (SP:P27829); contains similarity to Pfam family
PF00984 (UDP-glucose/GDP-mannose dehydrogenase family),
score=633.4, E=1.2e-186, N=1 [Salmonella typhimurium >
Length = 420
Score = 214 bits (539), Expect = 2e-54
Identities = 146/426 (34%), Positives = 213/426 (49%), Gaps = 30/426 (7%)
Query: 22 TIAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVE 81
TI+V GLG +GLP AA FA +VIGVDIN+ V+ +N GE HI E P L +VK VE
Sbjct: 5 TISVIGLGYIGLPTAAAFASRQKQVIGVDINQHAVDIINRGEIHIVE-PALGNVVKMAVE 63
Query: 82 AGRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITEA 141
G L+ATT + +AD +I VPT + + V A+ I+ L+KG +VI E+
Sbjct: 64 GGFLRATTTPV----EADAYLIAVPTPFKGDHDPDMAYVEAAAKSIAPVLKKGALVILES 119
Query: 142 TMPPGTTESLIPILEKSGLKL---------GDFGLAHAPERTMTGTAIRDITGQYPKIVG 192
T P G TE + L L D +A+ PER + G + ++ + +++G
Sbjct: 120 TSPVGATEQMAGWLAGMRTDLTFPQQAGEQADVNIAYCPERVLPGQVMVELI-KNDRVIG 178
Query: 193 ASDERTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHG 252
+Y+ I +G +++ + AE K+ E +RDVNIA ANEL+L C E G
Sbjct: 179 GMTPVCSARASALYK-IFLEGECVVTNSRTAEMCKLTENSFRDVNIAFANELSLICAEQG 237
Query: 253 LDAIEIFNAANTQPYCHLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREINDSMP 312
++ E+ AN P ++ PG GVGGHCI + PWF++ RLIRTARE+ND P
Sbjct: 238 INVWELIRLANRHPRVNILQPGPGVGGHCIAVDPWFIV-AQNPQQARLIRTAREVNDGKP 296
Query: 313 RHVVELTVRALND----AGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEW-GAE 367
VV+ A+ D K KI GL F+ + + +SPA+ + + + W E
Sbjct: 297 HWVVDQVKAAVTDCLAATDKRASEVKIACFGLAFKPNIDDLRESPAMGIAQSIARWHSGE 356
Query: 368 VYAYDP----LCTREDAERFGAKWKEDFKDVDAIVIVTDHREFKTLDLKEIAAEVRTKVI 423
+P L + D AK D +V++ DH EFK + V + +
Sbjct: 357 TLVVEPNIRQLPKKLDGLCTLAKLDAALAAADVLVMLVDHDEFKAIP----GDAVHQRYV 412
Query: 424 VDGRNV 429
VD + V
Sbjct: 413 VDTKGV 418
>pir||T44829 probable NDP-N-acetyl-D-galactosaminuronic acid dehydrogenase
[imported] - Acinetobacter lwoffii
>gi|6009990|emb|CAB57197.1| (AJ243431) putative
NDP-N-acetyl-D-galactosaminuronic acid dehydrogenase
[Acinetobacter lwoffii]
Length = 417
Score = 214 bits (539), Expect = 2e-54
Identities = 137/410 (33%), Positives = 216/410 (52%), Gaps = 35/410 (8%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
I V GLG +GLP AA FA +G KV GVD+N+ V+ +N G+ HI E P LD LV+ V
Sbjct: 8 ICVIGLGYIGLPTAATFAAHGVKVTGVDVNQHAVDMINQGKVHIVE-PDLDALVRDVVAQ 66
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITEAT 142
G+L A LA +AD I+ VPT D L+ + ++ ++ L+ G++VI E+T
Sbjct: 67 GKLSAQ----LAPTEADAYIVAVPTPFKDDYQPDLKYIEAASKALAPFLKSGNLVILEST 122
Query: 143 MPPGTTESLIPILEKSGLKLG---------DFGLAHAPERTMTGTAIRDITGQYPKIVGA 193
P TE + L ++ L D +AH PER + G ++++ +I+G
Sbjct: 123 SPVEATEQMSAWLSEARPDLSFPQQKGEEADILVAHCPERVLPGKVLQELISN-DRIIGG 181
Query: 194 SDERTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGL 253
R +A +Y+ I KG ++ + AE K+ E +RDVNIA ANEL++ C++ +
Sbjct: 182 MTPRCSKAACDLYK-IFVKGACIETNARTAEMCKLTENSFRDVNIAFANELSVICDKLDI 240
Query: 254 DAIEIFNAANTQPYCHLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREINDSMPR 313
+ E+ + AN P ++ PG GVGGHCI + PWF++ + RLIRTARE+ND+ P
Sbjct: 241 NVWELISLANRHPRVNILQPGPGVGGHCIAVDPWFIVAKTPE-QARLIRTAREVNDAKPE 299
Query: 314 HVVELTVRALND-----AGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEV 368
V++ + D K ++ I GL F+ + + +SPA+++ ++L E G +
Sbjct: 300 WVIDQVKIKIADFLQANPTKTIQDVTIACYGLAFKPDIDDLRESPALEITKKLAEQGFNI 359
Query: 369 YAYDPLCTREDAERFGAKWKEDFK--------DVDAIVIVTDHREFKTLD 410
A +P + AK + K D +I+ DHR+FK ++
Sbjct: 360 LAIEP-----NIHELPAKLPSNIKLIALKEHQQADIHLILVDHRQFKNMN 404
>pir||A83252 probable UDP-glucose/GDP-mannose dehydrogenase WbpA PA3159
[imported] - Pseudomonas aeruginosa (strain PAO1)
>gi|1545847|gb|AAC45852.1| (U50396) WbpA [Pseudomonas
aeruginosa] >gi|9949274|gb|AAG06547.1|AE004739_9
(AE004739) probable UDP-glucose/GDP-mannose
dehydrogenase WbpA [Pseudomonas aeruginosa]
Length = 436
Score = 213 bits (537), Expect = 3e-54
Identities = 144/429 (33%), Positives = 234/429 (53%), Gaps = 25/429 (5%)
Query: 12 VREAIKNGDVTIAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPG 71
V E K+ I + GLG +GLPL + G V+G+DI++ V+ +N G+ +I+ P
Sbjct: 7 VVEKFKSRQALIGIVGLGYVGLPLMLRYNAIGFDVLGIDIDDVKVDKLNAGQCYIEHIP- 65
Query: 72 LDELVKKNVEAGRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGL 131
+ A +ATTD + D +I+ VPT + + V + + + L
Sbjct: 66 --QAKIAKARASGFEATTD-FSRVSECDALILCVPTPLNKYREPDMSFVINTTDALKPYL 122
Query: 132 EKGDIVITEATMPPGTTES-LIPILEKSGLKLG-DFGLAHAPERTMTGTAIRDITGQYPK 189
G +V E+T PGTTE L+P +++ GL +G D L ++PER G + T PK
Sbjct: 123 RVGQVVSLESTTYPGTTEEELLPRVQEGGLVVGRDIYLVYSPEREDPGNPNFE-TRTIPK 181
Query: 190 IVGASDERTLEAVIGIYE-TINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWC 248
++G + LE I +YE I+R V+P+SS KAAE K+ E I+R VNI L NE+ +
Sbjct: 182 VIGGHTPQCLEVGIALYEQAIDR--VVPVSSTKAAEMTKLLENIHRAVNIGLVNEMKIVA 239
Query: 249 EEHGLDAIEIFNAANTQPYCHL-HMPGAGVGGHCIPIYPWFVINLAKK--TNVRLIRTAR 305
+ G+D E+ +AA T+P+ + PG G+GGHCIPI P+++ A++ + R I +
Sbjct: 240 DRMGIDIFEVVDAAATKPFGFTPYYPGPGLGGHCIPIDPFYLTWKAREYGLHTRFIELSG 299
Query: 306 EINDSMPRHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWG 365
E+N +MP +V+ + LN+AG+ +KGS++LVLG+ ++ V + +SP+++++ ++ G
Sbjct: 300 EVNQAMPEYVLGKLMDGLNEAGRALKGSRVLVLGIAYKKNVDDMRESPSVEIMELIEAKG 359
Query: 366 AEVYAYDPLC-----TREDAERFGAK--WKEDFKDVDAIVIVTDHREFKTLDLKEIAAEV 418
V DP RE ++ E+ DA+V+ TDH +F D + I AE
Sbjct: 360 GMVAYSDPHVPVFPKMREHHFELSSEPLTAENLARFDAVVLATDHDKF---DYELIKAE- 415
Query: 419 RTKVIVDGR 427
K++VD R
Sbjct: 416 -AKLVVDSR 423
>pir||B49350 hypothetical protein 379 (nfrC 3' region) - Escherichia coli
Length = 420
Score = 212 bits (533), Expect = 9e-54
Identities = 141/426 (33%), Positives = 217/426 (50%), Gaps = 30/426 (7%)
Query: 22 TIAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVE 81
TI+V GLG +GLP AA FA +VIGVDIN+ V+++N GE HI E P L +VK VE
Sbjct: 5 TISVIGLGYIGLPTAAAFASRQKQVIGVDINQHAVDTINRGEIHIVE-PDLASVVKTAVE 63
Query: 82 AGRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITEA 141
G L+A+T + +AD +I VPT + V A I+ L+KG +VI E+
Sbjct: 64 GGFLRASTTPV----EADAWLIAVPTPFKGDHEPDMTYVESAARSIAPVLKKGALVILES 119
Query: 142 TMPPGTTESLIPILEKSGLKL---------GDFGLAHAPERTMTGTAIRDITGQYPKIVG 192
T P G+TE + L + L D +A+ PER + G + ++ + +++G
Sbjct: 120 TSPVGSTEKMAEWLAEMRPDLTFPQQVGEQADVNIAYCPERVLPGQVMVELI-KNDRVIG 178
Query: 193 ASDERTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHG 252
+Y+ I +G +++ + AE K+ E +RDVNIA ANEL+L C + G
Sbjct: 179 GMTPVCSARASELYK-IFLEGECVVTNSRTAEMCKLTENSFRDVNIAFANELSLICADQG 237
Query: 253 LDAIEIFNAANTQPYCHLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREINDSMP 312
++ E+ AN P ++ PG GVGGHCI + PWF++ RLIRTARE+ND P
Sbjct: 238 INVWELIRLANRHPRVNILQPGPGVGGHCIAVDPWFIV-AQNPQQARLIRTAREVNDHKP 296
Query: 313 RHVVELTVRALND----AGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEW-GAE 367
V++ A+ D K KI GL F+ + + +SPA+++ + +W E
Sbjct: 297 FWVIDQVKAAVADCLAATDKRASELKIACFGLAFKPNIDDLRESPAMEIAELIAQWHSGE 356
Query: 368 VYAYDPLCTREDAERFG----AKWKEDFKDVDAIVIVTDHREFKTLDLKEIAAEVRTKVI 423
+P + + G A+ E D +V++ DH +FK ++ V + +
Sbjct: 357 TLVVEPNIHQLPKKLTGLCTLAQLDEALATADVLVMLVDHSQFKVIN----GDNVHQQYV 412
Query: 424 VDGRNV 429
VD + V
Sbjct: 413 VDAKGV 418
>sp|P27829|WECC_ECOLI UDP-N-ACETYL-D-MANNOSAMINURONIC ACID DEHYDROGENASE (UDP-MANNACA
DEHYDROGENASE) >gi|7449840|pir||F65182 UDP-ManNAc
dehydrogenase - Escherichia coli
>gi|2367284|gb|AAC76792.1| (AE000455)
UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase;
synthesis of enterobacterial common antigen (ECA)
[Escherichia coli K12]
Length = 420
Score = 210 bits (530), Expect = 2e-53
Identities = 141/426 (33%), Positives = 217/426 (50%), Gaps = 30/426 (7%)
Query: 22 TIAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVE 81
TI+V GLG +GLP AA FA +VIGVDIN+ V+++N GE HI E P L +VK VE
Sbjct: 5 TISVIGLGYIGLPTAAAFASRQKQVIGVDINQHAVDTINRGEIHIVE-PDLASVVKTAVE 63
Query: 82 AGRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITEA 141
G L+A+T + +AD +I VPT + V A I+ L+KG +VI E+
Sbjct: 64 GGFLRASTTPV----EADRWLIAVPTPFKGDHEPDMTYVESAARSIAPVLKKGALVILES 119
Query: 142 TMPPGTTESLIPILEKSGLKL---------GDFGLAHAPERTMTGTAIRDITGQYPKIVG 192
T P G+TE + L + L D +A+ PER + G + ++ + +++G
Sbjct: 120 TSPVGSTEKMAEWLAEMRPDLTFPQQVGEQADVNIAYCPERVLPGQVMVELI-KNDRVIG 178
Query: 193 ASDERTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHG 252
+Y+ I +G +++ + AE K+ E +RDVNIA ANEL+L C + G
Sbjct: 179 GMTPVCSARASELYK-IFLEGECVVTNSRTAEMCKLTENSFRDVNIAFANELSLICADQG 237
Query: 253 LDAIEIFNAANTQPYCHLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREINDSMP 312
++ E+ AN P ++ PG GVGGHCI + PWF++ RLIRTARE+ND P
Sbjct: 238 INVWELIRLANRHPRVNILQPGPGVGGHCIAVDPWFIV-AQNPQQARLIRTAREVNDHKP 296
Query: 313 RHVVELTVRALND----AGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEW-GAE 367
V++ A+ D K KI GL F+ + + +SPA+++ + +W E
Sbjct: 297 FWVIDQVKAAVADCLAATDKRASELKIACFGLAFKPNIDDLRESPAMEIAELIAQWHSGE 356
Query: 368 VYAYDPLCTREDAERFG----AKWKEDFKDVDAIVIVTDHREFKTLDLKEIAAEVRTKVI 423
+P + + G A+ E D +V++ DH +FK ++ V + +
Sbjct: 357 TLVVEPNIHQLPKKLTGLCTLAQLDEALATADVLVMLVDHSQFKVIN----GDNVHQQYV 412
Query: 424 VDGRNV 429
VD + V
Sbjct: 413 VDAKGV 418
>pir||T44509 Vi polysaccharide biosynthetic protein [imported] - Plesiomonas
shigelloides >gi|6009648|dbj|BAA85006.1| (AB025970)
ORF1P [Plesiomonas shigelloides]
>gi|10442655|gb|AAG17408.1|AF285970_2 (AF285970) WbgT
[Plesiomonas shigelloides]
Length = 437
Score = 203 bits (512), Expect = 3e-51
Identities = 145/404 (35%), Positives = 213/404 (51%), Gaps = 21/404 (5%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKV--IGVDINERVVNSVNNGENHIKEEPGLDELVKKNV 80
I + GLG +GLPLA F G KV IG DIN+ ++ + NG + E L+ L
Sbjct: 21 IGIIGLGYVGLPLAVEF---GKKVTTIGFDINKSRIDELRNGHDSTLECSNLELL----- 72
Query: 81 EAGRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITE 140
EA +L + A K+ +V I+ VPT D L + +E + K ++KGD++I E
Sbjct: 73 EATKLTYACS-LDALKECNVFIVTVPTPIDKHKQPDLTPLIKASETLGKIIKKGDVIIYE 131
Query: 141 ATMPPGTTES-LIPILEK-SGLKLG-DFGLAHAPERTMTGTAIRDITGQYPKIVGASDER 197
+T+ PG TE IP++EK SGLK DF ++PER G +T K+ S
Sbjct: 132 STVYPGATEEDCIPVVEKVSGLKFNIDFFAGYSPERINPGDKEHRVTNIL-KVTSGSTPD 190
Query: 198 TLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIE 257
E V +Y+ I G SSIK AEA KV E RDVNIAL NEL++ + G+D +E
Sbjct: 191 VAEYVDQLYKLIITVGTHKASSIKVAEAAKVIENTQRDVNIALINELSIIFNKLGIDTLE 250
Query: 258 IFNAANTQPYCHLHMPGAGVGGHCIPIYPWFVINLAKKTNVR--LIRTAREINDSMPRHV 315
+ AA T+ PG VGGHCI + P+++ + A+ +I R +NDSM ++V
Sbjct: 251 VLEAAGTKWNFLPFRPGL-VGGHCIGVDPYYLTHKAQSVGYHPEMILAGRRLNDSMGQYV 309
Query: 316 VELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYAYDPLC 375
V V+ + ++G+ +LV+GLTF+ + + ID+I ELKE+ + DP C
Sbjct: 310 VSQLVKKMLKQRIQVEGANVLVMGLTFKENCPDLRNTKVIDIISELKEYNINIDIIDPWC 369
Query: 376 TREDAE-RFGAKWKEDFK--DVDAIVIVTDHREFKTLDLKEIAA 416
+ ++A+ +G ED K DAI+I H EF+ + I A
Sbjct: 370 STDEAQHEYGLTLCEDPKVNHYDAIIIAVAHNEFREMGESAIRA 413
>pir||T44520 lipopolysaccharide biosynthesis protein [imported] - Shigella
sonnei >gi|6009797|dbj|BAA85071.1| (AB028135) ORF1S
[Shigella sonnei] >gi|10442666|gb|AAG17418.1|AF285971_2
(AF285971) WbgT [Shigella sonnei]
Length = 437
Score = 203 bits (512), Expect = 3e-51
Identities = 145/404 (35%), Positives = 213/404 (51%), Gaps = 21/404 (5%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKV--IGVDINERVVNSVNNGENHIKEEPGLDELVKKNV 80
I + GLG +GLPLA F G KV IG DIN+ ++ + NG + E L+ L
Sbjct: 21 IGIIGLGYVGLPLAVEF---GKKVTTIGFDINKSRIDELRNGHDSTLECSNLELL----- 72
Query: 81 EAGRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITE 140
EA +L + A K+ +V I+ VPT D L + +E + K ++KGD++I E
Sbjct: 73 EATKLTYACS-LDALKECNVFIVTVPTPIDKHKQPDLTPLIKASETLGKIIKKGDVIIYE 131
Query: 141 ATMPPGTTES-LIPILEK-SGLKLG-DFGLAHAPERTMTGTAIRDITGQYPKIVGASDER 197
+T+ PG TE IP++EK SGLK DF ++PER G +T K+ S
Sbjct: 132 STVYPGATEEDCIPVVEKVSGLKFNIDFFAGYSPERINPGDKEHRVTNIL-KVTSGSTPD 190
Query: 198 TLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIE 257
E V +Y+ I G SSIK AEA KV E RDVNIAL NEL++ + G+D +E
Sbjct: 191 VAEYVDQLYKLIITVGTHKASSIKVAEAAKVIENTQRDVNIALINELSIIFNKLGIDTLE 250
Query: 258 IFNAANTQPYCHLHMPGAGVGGHCIPIYPWFVINLAKKTNVR--LIRTAREINDSMPRHV 315
+ AA T+ PG VGGHCI + P+++ + A+ +I R +NDSM ++V
Sbjct: 251 VLEAAGTKWNFLPFRPGL-VGGHCIGVDPYYLTHKAQSVGYHPEMILAGRRLNDSMGQYV 309
Query: 316 VELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYAYDPLC 375
V V+ + ++G+ +LV+GLTF+ + + ID+I ELKE+ + DP C
Sbjct: 310 VSQLVKKMLKQRIQVEGANVLVMGLTFKENCPDLRNTKVIDIISELKEYNINIDIIDPWC 369
Query: 376 TREDAE-RFGAKWKEDFK--DVDAIVIVTDHREFKTLDLKEIAA 416
+ ++A+ +G ED K DAI+I H EF+ + I A
Sbjct: 370 STDEAQHEYGLTLCEDPKVNHYDAIIIAVAHNEFREMGESAIRA 413
>sp|P39861|CAPL_STAAU CAPL PROTEIN >gi|506708|gb|AAA64651.1| (U10927) CapL
[Staphylococcus aureus]
Length = 424
Score = 196 bits (492), Expect = 6e-49
Identities = 138/420 (32%), Positives = 213/420 (49%), Gaps = 18/420 (4%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
IAV GLG +GLP+A F N KVIG DINE + + N + E ++L N+E
Sbjct: 5 IAVVGLGYVGLPVAVTFG-NKHKVIGFDINESRIKELKNNYDRTNEVTE-NKLKNTNIEY 62
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITEAT 142
T KKAD +II VPT D L + +E + K + IV+ E+T
Sbjct: 63 ------TSNAEDLKKADFIIIAVPTPIDKHNKPDLLPLLKASETVGKVITPDTIVVYEST 116
Query: 143 MPPGTTES-LIPILEK-SGLKLG-DFGLAHAPERTMTGTAIRDITGQYPKIVGASDERTL 199
+ PG TE +P+LEK SGL G DF + ++PER G + K+V L
Sbjct: 117 VYPGATEEECVPVLEKYSGLVCGKDFFVGYSPERINPGDKVHTFE-TITKVVSGQTLEVL 175
Query: 200 EAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIEIF 259
E V +Y ++ GV SSIK AEA KV E RDVNIAL NELA+ ++ +D E+
Sbjct: 176 EIVADVYSSVVTAGVHKASSIKVAEAAKVIENTQRDVNIALMNELAIIFDKLDIDTNEVL 235
Query: 260 NAANTQPYCHLHMPGAGVGGHCIPIYPWFVINLAKKT--NVRLIRTAREINDSMPRHVVE 317
A+ T+ + L+ VGGHCI + P+++ + A++ + +I R IND+M +++
Sbjct: 236 KASGTK-WNFLNFKPGLVGGHCIGVDPYYLTHKAQEVGHHPEVILAGRRINDNMAKYIAS 294
Query: 318 LTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYAYDPLCTR 377
++ L G ++G+ + VLGLTF+ + + I +I ELKE+G V D +
Sbjct: 295 NVIKELLKQGLEVQGATVNVLGLTFKENCPDLRNTKVIHIIEELKEYGLNVTVNDVEADK 354
Query: 378 EDAERFGAKWKEDFKD---VDAIVIVTDHREFKTLDLKEIAAEVRTKVIVDGRNVIHPEE 434
+A++F D K+ VD ++ H+++ I ++ D + +I+ +E
Sbjct: 355 NEAKKFFGLDLIDTKELKMVDVVLFAVPHKDYMENKKDYINLVKDCGIVFDIKGIINSDE 414
>gb|AAF23997.1| (AF035937) WbpO [Pseudomonas aeruginosa]
Length = 422
Score = 194 bits (487), Expect = 2e-48
Identities = 136/408 (33%), Positives = 203/408 (49%), Gaps = 27/408 (6%)
Query: 20 DVTIAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKN 79
D+ +AV GLG +GLPLA F V+G DIN+ + + G + E
Sbjct: 3 DLKVAVVGLGYVGLPLAVEFGKKRT-VVGFDINQGRIAELRQGIDSTLE----------- 50
Query: 80 VEAGRLKATTD-----GILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKG 134
V+A LK ++ + +K +V I+ VPT D+ L + +E I K L+KG
Sbjct: 51 VDAAELKEASELSFTFNLQDLQKCNVFIVTVPTPIDEHKQPDLTPLVKASESIGKVLKKG 110
Query: 135 DIVITEATMPPGTTES-LIPILEK-SGLKLG-DFGLAHAPERTMTGTAIRDITGQYPKIV 191
DIVI E+T+ PG TE +P+LEK SGL+ DF ++PER G ++ K+
Sbjct: 111 DIVIYESTVYPGATEEDCVPVLEKFSGLRFNEDFFAGYSPERINPGDKEHRVSS-IKKVT 169
Query: 192 GASDERTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEH 251
S E V +Y I G SSIK AEA KV E RD+NIAL NELA+
Sbjct: 170 SGSTPEIAELVDSLYREIITAGTHKASSIKVAEAAKVIENTQRDLNIALINELAIIFNRM 229
Query: 252 GLDAIEIFNAANTQPYCHLHMPGAGVGGHCIPIYPWFVINLAKKTNVR--LIRTAREIND 309
G+D + AA T+ PG VGGHCI + P+++ + A+ +I R +ND
Sbjct: 230 GIDTEAVLKAAGTKWNFMPFRPGL-VGGHCIGVDPYYLTHKAQSIGYHPEIILAGRRLND 288
Query: 310 SMPRHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVY 369
M +VV V+A+ + G+++L++GLTF+ + + +D++REL E+ +V
Sbjct: 289 GMGAYVVSQLVKAMLKRRIHVDGARVLLMGLTFKENCPDLRNTKVVDIVRELAEYNIQVD 348
Query: 370 AYDPLCTREDA-ERFGAK--WKEDFKDVDAIVIVTDHREFKTLDLKEI 414
+DP + EDA +G D I++ H EFK + + I
Sbjct: 349 VFDPWVSAEDAMHEYGITPVGTPSHGAYDGIILAVAHSEFKNMGAENI 396
>pir||S30681 hypothetical protein o379 - Escherichia coli
>gi|148190|gb|AAA67587.1| (M87049) possibly rffD;
(UDP-ManNAc dehydrogenase) [Escherichia coli]
Length = 379
Score = 192 bits (484), Expect = 5e-48
Identities = 125/356 (35%), Positives = 188/356 (52%), Gaps = 22/356 (6%)
Query: 22 TIAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVE 81
TI+V GLG +GLP A FA +VIGVDIN+ V+++N GE HI E P L +VK VE
Sbjct: 5 TISVIGLGYIGLPTRA-FASRQKQVIGVDINQHAVDTINRGEIHIVE-PDLASVVKTAVE 62
Query: 82 AGRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITEA 141
G L+A+T + +AD +I VPT + V A I+ L+KG +VI E+
Sbjct: 63 GGFLRASTTPV----EADRWLIAVPTPFKGDHEPDMTYVESAARSIAPVLKKGALVILES 118
Query: 142 TMPPGTTESLIPILEKSGLKL---------GDFGLAHAPERTMTGTAIRDITGQYPKIVG 192
T P G+TE + L + L D +A+ PER + G + ++ + +++G
Sbjct: 119 TSPVGSTEKMAEWLAEMRPDLTFPQQVGEQADVNIAYCPERVLPGQVMVELI-KNDRVIG 177
Query: 193 ASDERTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHG 252
+Y+ I +G +++ + AE K+ E +RDVNIA ANEL+L C + G
Sbjct: 178 GMTPVCSARASELYK-IFLEGECVVTNSRTAEMCKLTENSFRDVNIAFANELSLICADQG 236
Query: 253 LDAIEIFNAANTQPYCHLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREINDSMP 312
++ E+ AN P ++ PG GVGGHCI + PWF++ RLIRTARE+ND P
Sbjct: 237 INVWELIRLANRHPRVNILQPGPGVGGHCIAVDPWFIV-AQNPQQARLIRTAREVNDHKP 295
Query: 313 RHVVELTVRALND----AGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEW 364
V++ A+ D K KI GL F+ + + +SPA+++ + +W
Sbjct: 296 FWVIDQVKAAVADCLAATDKRASELKIACFGLAFKPNIDDLRESPAMEIAELIAQW 351
>gi|11498204 UDP-glucose dehydrogenase (ugd-2) [Archaeoglobus fulgidus]
>gi|7431387|pir||D69324 UDP-glucose dehydrogenase
(ugd-2) homolog - Archaeoglobus fulgidus
>gi|2650028|gb|AAB90645.1| (AE001064) UDP-glucose
dehydrogenase (ugd-2) [Archaeoglobus fulgidus]
Length = 465
Score = 190 bits (478), Expect = 3e-47
Identities = 139/438 (31%), Positives = 230/438 (51%), Gaps = 34/438 (7%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
IA+ G G +G+ FA+ G +++ +D++ER V +N+ + I E GL+EL+KKN
Sbjct: 45 IAILGSGYVGIVTGIGFAELGHEIVFIDVDERKVEMLNSSKPPIYER-GLEELMKKN--R 101
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGD---IVIT 139
G+ +ATTD A + +++ I V T + G++ L+ +++I K L+ D +V+
Sbjct: 102 GKYRATTDYREALESSELTFICVGTPSKGDGSIDLKYAESASKEIGKALKNNDNFHVVVV 161
Query: 140 EATMPPGTTESLI-PILEK-SGLK-LGDFGLAHAPERTMTGTAIRDITGQYPKIVGASDE 196
++T+ PGTTE I PI+EK SG K DFGLA PE G A+ D ++G DE
Sbjct: 162 KSTVVPGTTEDKIKPIIEKESGKKAFEDFGLAMNPEFLREGNAVYDFFNPDRIVIGVKDE 221
Query: 197 RTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAI 256
RT + +Y+ + +I + IK AE +K + I+ ANE+ C++ +D
Sbjct: 222 RTKSVLEELYKPFDCPKLI--TEIKTAEMIKYASNAFLATKISFANEIGNICKKLRIDVY 279
Query: 257 EIFNAANTQPYCH--LHMPGAGVGGHCIPIYPWFVINLAKKT--NVRLIRTAREINDSMP 312
++F + G G GG C P +I +++ N ++++ E+N+ P
Sbjct: 280 KVFEGVGLDHRINPSFFRAGIGFGGSCFPKDVRALIRKSEELGENPKILKAVMEVNERQP 339
Query: 313 RHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYAYD 372
++EL + + + ++G KI VLGL F+ + +S AI +++ L E GAE+ AYD
Sbjct: 340 LKMIELLKKHIPN----LRGKKIGVLGLAFKPDTDDVRESRAIPIVKALLEEGAEIIAYD 395
Query: 373 PLCTREDAERF-GAKWKEDFKDV----DAIVIVTDHREFKTLDLKEIAAEVRTKVIVDGR 427
P + F ++ +DV DA++IVT+ +EF+ LD K+++DGR
Sbjct: 396 PKAIENFRKFFPQVEYANSAEDVITKSDAVLIVTEWKEFEELDYS-------GKIVIDGR 448
Query: 428 NVIHPEEAKKLGFIYKGV 445
V E+A K IYKGV
Sbjct: 449 RV---EKAMKEAKIYKGV 463
>gb|AAA84869.1| (U34305) ORF1; Method: conceptual translation supplied by author
[Shigella sonnei]
Length = 416
Score = 186 bits (468), Expect = 4e-46
Identities = 139/404 (34%), Positives = 209/404 (51%), Gaps = 22/404 (5%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKV--IGVDINERVVNSVNNGENHIKEEPGLDELVKKNV 80
I + GLG +GLPLA F G KV IG DIN+ ++ + NG + E L+ L
Sbjct: 10 IGIIGLGYVGLPLAVEF---GKKVTTIGFDINKSRIDELRNGHDSTLECSNLELL----- 61
Query: 81 EAGRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITE 140
EA +L + A K+ +V I+ VP D L + +E + K ++KGD++I E
Sbjct: 62 EATKLTYACS-LDALKECNVFIVTVPAPIDKHKQPDLTPLIKASETLGKIIKKGDVIIYE 120
Query: 141 ATMPPGTTES-LIPILEK-SGLKLG-DFGLAHAPERTMTGTAIRDITGQYPKIVGASDER 197
+T+ PG TE IP++EK SGLK DF ++PER G +T K+ S
Sbjct: 121 STVYPGATEEDCIPVVEKVSGLKFNIDFFAGYSPERINPGDKEHRVTNIL-KVASGSTPD 179
Query: 198 TLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIE 257
E V +Y+ I G SSIK E ++ RDVNIAL NEL++ + G+D +E
Sbjct: 180 VAEYVDQLYKLIITVGTHKASSIKV-ERLQSNVNTQRDVNIALINELSIIFNKLGIDTLE 238
Query: 258 IFNAANTQPYCHLHMPGAGVGGHCIPIYPWFVINLAKKTNVR--LIRTAREINDSMPRHV 315
+ AA T+ PG VGGHCI + P+++ + A+ +I R +NDSM ++V
Sbjct: 239 VLEAAGTKWNLLPFRPGL-VGGHCIGVDPYYLTHKAQSVGYHPEMILAGRRLNDSMGQYV 297
Query: 316 VELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYAYDPLC 375
V V+ + ++G+ +LV+GLTF+ + + ID+I ELKE+ + DP C
Sbjct: 298 VSQLVKKMLKQRIQVEGANVLVMGLTFKENCPDLRNTKVIDIISELKEYNINIDIIDPWC 357
Query: 376 TREDAE-RFGAKWKEDFK--DVDAIVIVTDHREFKTLDLKEIAA 416
+ ++A+ +G ED K DAI+I H EF+ + I A
Sbjct: 358 STDEAQHEYGLTLCEDPKVNHYDAIIIAVAHNEFREMGESAIRA 401
>sp|Q04972|VIPA_SALTI VI POLYSACCHARIDE BIOSYNTHESIS PROTEIN VIPA/TVIB
>gi|1361287|pir||B36892 Vi polysaccharide biosynthetic
protein VipA - Salmonella typhi
>gi|475033|dbj|BAA03192.1| (D14156) WcdA protein
[Salmonella typhi] >gi|581779|emb|CAA47991.1| (X67785)
wcdA; ORF2 in citation [1] [Salmonella typhi]
Length = 425
Score = 185 bits (465), Expect = 8e-46
Identities = 134/425 (31%), Positives = 221/425 (51%), Gaps = 18/425 (4%)
Query: 20 DVTIAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKN 79
+V IA+ GLG +GLPLA F + +V+G D+N++ + + NG + L+ ++
Sbjct: 6 EVKIAIIGLGYVGLPLAVEFGKS-RQVVGFDVNKKRILELKNGV-----DVNLETTEEEL 59
Query: 80 VEAGRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVIT 139
EA LK T++ I K+ + II VPT + L + +E + L +GDIV+
Sbjct: 60 REARYLKFTSE-IEKIKECNFYIITVPTPINTYKQPDLTPLIKASETVGTVLNRGDIVVY 118
Query: 140 EATMPPGTTES-LIPILEK-SGLKLG-DFGLAHAPERTMTGTAIRDITGQYPKIVGASDE 196
E+T+ PG TE +PIL + SG+ DF + ++PER G +T KI S
Sbjct: 119 ESTVYPGCTEEECVPILARMSGMTFNQDFYVGYSPERINPGDKKHRLTN-IKKITSGSTA 177
Query: 197 RTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAI 256
+ E + +Y+ I G SIK AEA KV E RD+NIAL NELA+ +D
Sbjct: 178 QIAELIDEVYQQIISAGTYKAESIKVAEAAKVIENTQRDLNIALVNELAIIFNRLNIDTE 237
Query: 257 EIFNAANTQPYCHLHMPGAGVGGHCIPIYPWFVINLAKKTNV--RLIRTAREINDSMPRH 314
+ AA ++ PG VGGHCI + P+++ + ++ +I R +ND+M +
Sbjct: 238 AVLRAAGSKWNFLPFRPGL-VGGHCIGVDPYYLTHKSQGIGYYPEIILAGRRLNDNMGNY 296
Query: 315 VVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYAYDPL 374
V E ++A+ G ++GS +L+LG TF+ + + IDV++EL ++ +V +DP
Sbjct: 297 VSEQLIKAMIKKGINVEGSSVLILGFTFKENCPDIRNTRIIDVVKELGKYSCKVDIFDPW 356
Query: 375 CTREDAER-FGAKWKEDFKD--VDAIVIVTDHREFKTLDLKEIAAEVRTK-VIVDGRNVI 430
E+ R +G + K DAI++ H++FK + ++I + K V+ D + V+
Sbjct: 357 VDAEEVRREYGIIPVSEVKSSHYDAIIVAVGHQQFKQMGSEDIRGFGKDKHVLYDLKYVL 416
Query: 431 HPEEA 435
E++
Sbjct: 417 PAEQS 421
>pir||F69727 biosynthesis of teichuronic acid (UDP-glucose 6-dehydrogenase) tuaD
- Bacillus subtilis >gi|2454559|gb|AAB94865.1|
(AF015609) UDP-glucose dehydrogenase [Bacillus subtilis]
>gi|2636084|emb|CAB15575.1| (Z99122) UDP-glucose
6-dehydrogenase [Bacillus subtilis]
Length = 461
Score = 183 bits (460), Expect = 3e-45
Identities = 125/435 (28%), Positives = 211/435 (47%), Gaps = 17/435 (3%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
IAV G G +GL FA+ G KV+ DI+E + S+ NG I E PGL +LV+KNV
Sbjct: 4 IAVIGTGYVGLVSGTCFAEIGNKVVCCDIDESKIRSLKNGVIPIYE-PGLADLVEKNVLD 62
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITEAT 142
RL T D A + +D++ I V T G L V A+ I + L +++ ++T
Sbjct: 63 QRLTFTNDIPSAIRASDIIYIAVGTPMSKTGEADLTYVKAAAKTIGEHLNGYKVIVNKST 122
Query: 143 MPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASDERTLEAV 202
+P GT + + I++K+ F + PE G+AI D ++G++ + +
Sbjct: 123 VPVGTGKLVQSIVQKASKGRYSFDVVSNPEFLREGSAIHDTMNMERAVIGSTSHKAAAII 182
Query: 203 IGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIEIFNAA 262
+++ + + +++++AE +K + I+ N++A CE G D ++ +
Sbjct: 183 EELHQPFH--APVIKTNLESAEMIKYAANAFLATKISFINDIANICERVGADVSKVADGV 240
Query: 263 NTQPYC--HLHMPGAGVGGHCIPIYPWFVINLAKKTN--VRLIRTAREINDSMPRHVVEL 318
G G GG C P ++ +AK +LI E N+ H+V+
Sbjct: 241 GLDSRIGRKFLKAGIGFGGSCFPKDTTALLQIAKSAGYPFKLIEAVIETNEKQRVHIVDK 300
Query: 319 TVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYAYDPLCTRE 378
+ + +KG I VLGL F+ + +PA+D+I L++ GA V AYDP+ E
Sbjct: 301 LLTVMGS----VKGRTISVLGLAFKPNTNDVRSAPALDIIPMLQQLGAHVKAYDPIAIPE 356
Query: 379 DAERFGAKWK------EDFKDVDAIVIVTDHREFKTLDLKEIAAEVRTKVIVDGRNVIHP 432
+ G + + +D DA +I+TD E K ++L ++ ++ VI+DGRN+
Sbjct: 357 ASAILGEQVEYYTDVYAAMEDTDACLILTDWPEVKEMELVKVKTLLKQPVIIDGRNLFSL 416
Query: 433 EEAKKLGFIYKGVGR 447
EE + G+IY +GR
Sbjct: 417 EEMQAAGYIYHSIGR 431
>gb|AAD40718.1|AF048749_14 (AF048749) putative UDP-glucose-6 dehydrogenase [Bacteroides
fragilis]
Length = 425
Score = 182 bits (456), Expect = 1e-44
Identities = 134/429 (31%), Positives = 218/429 (50%), Gaps = 28/429 (6%)
Query: 20 DVTIAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKN 79
++ IAV GLG +GLPLA +F+ + IG D+N+ V+++N+G + E D+L++K
Sbjct: 3 ELKIAVIGLGYVGLPLARLFSTK-YECIGFDLNQSRVDALNSGHDMTLEVS--DDLLRKA 59
Query: 80 VEAGRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVIT 139
+E G K T++ I + ++ VPT D L + + + K + KGDIV+
Sbjct: 60 LENG-FKCTSN-IDEISNCNFYVVAVPTPVDLNNRPDLTPLIGASTTVGKVISKGDIVVY 117
Query: 140 EATMPPGTTES-LIPILEK-SGLKLG-DFGLAHAPERTMTGTAIRDITGQYPKIVGASDE 196
E+T+ PG TE +P++E+ SGL DF ++PER G + + K+ S
Sbjct: 118 ESTVYPGVTEEECLPVVEEVSGLTYNVDFYAGYSPERINPGDKEHTVE-KIKKVTSGSTP 176
Query: 197 RTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAI 256
+ V +Y ++ G SIK AEA K+ E RDVNIA NEL+ G+D
Sbjct: 177 EIADIVDSVYNSVLVNGTHKAPSIKVAEASKIIENSQRDVNIAFMNELSKIFNAMGIDTN 236
Query: 257 EIFNAANTQPYCHLHMPGAGVGGHCIPIYPWFVINLAKKTNV--RLIRTAREINDSMPRH 314
++ AA+++ PG VGGHCI + P+++I A+ V R++ AR +ND M +
Sbjct: 237 DVIEAASSKWNFIKLKPGL-VGGHCISVDPYYLIQKAQVYGVLPRIMSAARRLNDGMGDY 295
Query: 315 VVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYAYDPL 374
V +R +N G +K SKIL+LG TF+ + + ID+ L E+ +++ YD
Sbjct: 296 VANQVIRLMNKKGILVKDSKILLLGFTFKEDCPDIRNTKVIDIYSTLHEYTSDITVYDAW 355
Query: 375 C-TREDAERFG-----AKWKEDFKDVDAIVIVTDHREFKTLDLKEI----------AAEV 418
+ + A +G A DA+V+ H+EF+ ++++ V
Sbjct: 356 ANSAKVAHEYGISILTAGLDNLVGQFDAVVLCVGHKEFRHMNIRGFLRSDMGVVYDVKAV 415
Query: 419 RTKVIVDGR 427
+K I+DGR
Sbjct: 416 LSKDIIDGR 424
>sp|O54068|UDG_RHIME UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH)
Length = 437
Score = 182 bits (456), Expect = 1e-44
Identities = 139/441 (31%), Positives = 218/441 (48%), Gaps = 24/441 (5%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
I + G G +GL FAD G V+ VD +E ++++ G+ I E PGLD LV NV +
Sbjct: 3 ITMIGAGYVGLVSGVCFADFGHDVVCVDKDEGKISALKKGQIPIFE-PGLDHLVASNVAS 61
Query: 83 GRLKATTDGILAAKKADVMIILV--PTLADDRGNLKLESVYDVAEKISKGLEKGDIVITE 140
GRL T D A +DV+ I V P+ D G+ L VY A +I+ L+ +V+T+
Sbjct: 62 GRLNFTDDLKTAVAASDVVFIAVGTPSRRGD-GHADLSYVYAAAREIAANLQGFTVVVTK 120
Query: 141 ATMPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGA--SDERT 198
+T+P GT + + I+ ++ D + PE G AI D ++G SD R
Sbjct: 121 STVPVGTGDEVERIIRETN-PAADVTVVSNPEFLREGAAIEDFKRPDRIVIGVDGSDGRA 179
Query: 199 LEAVIGIYETIN-RKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIE 257
E + +Y + + + ++ + +E +K + + I NE+A CE+ G + +
Sbjct: 180 REVMTEVYRPLYLNQSPLVFTTRRTSELIKYAGNAFLAMKITFINEIADLCEKVGANVQD 239
Query: 258 IFNAANTQPYC---HLHMPGAGVGGHCIPIYPWFVINLAKK--TNVRLIRTAREINDSMP 312
+ LH G G GG C P ++ A+ T VRL+ T +ND+
Sbjct: 240 VARGIGLDGRIGSKFLHA-GPGYGGSCFPKDTLALVKTAQDHDTPVRLVETTVAVNDNRK 298
Query: 313 RHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYAYD 372
R + + A AG ++GSKI VLGLTF+ + SPAI V++ L++ GA V YD
Sbjct: 299 RAMGRKVIAA---AGGDIRGSKIAVLGLTFKPNTDDMRDSPAIAVVQALQDAGARVTGYD 355
Query: 373 PLCTREDAERF--GAKWKED----FKDVDAIVIVTDHREFKTLDLKEIAAEVRTKVIVDG 426
P E+A + G D + DA+VI+T+ EF+ LD + + ++T ++VD
Sbjct: 356 PE-GMENARKLIEGLDCARDPYEAAAEADALVIITEWNEFRALDFDRLKSTMKTPLLVDL 414
Query: 427 RNVIHPEEAKKLGFIYKGVGR 447
RN+ +E K GF Y +GR
Sbjct: 415 RNIYRKDEVAKHGFRYASIGR 435
>pir||H75095 udp-glucose dehydrogenase (ugd) PAB0770 - Pyrococcus abyssi
(strain Orsay) >gi|5458581|emb|CAB50069.1| (AJ248286)
UDP-glucose dehydrogenase (ugd) [Pyrococcus abyssi]
Length = 427
Score = 181 bits (455), Expect = 1e-44
Identities = 141/445 (31%), Positives = 230/445 (51%), Gaps = 40/445 (8%)
Query: 21 VTIAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNV 80
+ +++ G G +GL F G +VI VD++E V +NN + I EE GL+EL+++
Sbjct: 1 MNVSIIGSGYVGLVTGMGFVKLGNRVIFVDVDEWKVRVINNAQPPIYEE-GLEELMQEF- 58
Query: 81 EAGRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGD---IV 137
G+ AT + A +D+ I V T + G + L V + A++I K L++ D IV
Sbjct: 59 -KGKYYATNNYREAILNSDITFITVGTPSKPDGTIDLTYVKNAAKEIGKALKEKDNFHIV 117
Query: 138 ITEATMPPGTTESLI-PILEK-SGLK-LGDFGLAHAPERTMTGTAIRDITGQYPKIVGAS 194
+ ++T+ PGTTE +I PILEK SG K DFGLA PE G A++D ++G
Sbjct: 118 VVKSTVLPGTTEGVIRPILEKYSGKKAFQDFGLAMNPEFLREGVALKDFLNPDRIVIGVQ 177
Query: 195 DERTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLD 254
DERT + + +YE N + + IK AE +K + I+ ANE+ C++ G+D
Sbjct: 178 DERTKKVLEKLYEPFNAPKL--FTDIKTAEMIKYASNAFLATKISFANEIGNICKKLGID 235
Query: 255 AIEIFNAANTQPYC--HLHMPGAGVGGHCIPIYPWFVINLAKK--TNVRLIRTAREINDS 310
+ ++F H G G GG C P +I A++ + +++ ++N+
Sbjct: 236 SWKVFEGVGLDHRISPHFFRSGIGFGGSCFPKDLKALIKKAEELGEDPIILKAVLQVNER 295
Query: 311 MPRHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYA 370
P ++EL + + + +K K+ VLGL F+ + ++ A VI++L E GA+V A
Sbjct: 296 QPLKLIELLKKHVPN----LKDMKVGVLGLAFKPNTDDVRETRAYIVIKKLLEEGAKVIA 351
Query: 371 YDPLCTREDAERF----------GAKWKEDFKDVDAIVIVTDHREFKTLDLKEIAAEVRT 420
YDP E+ +RF +E ++VD I+I+T+ R+F++LD
Sbjct: 352 YDPK-AMENFKRFYPDVGRQISYANSAEEVLREVDVILILTEWRDFESLDYS-------G 403
Query: 421 KVIVDGRNVIHPEEAKKLGFIYKGV 445
K+++DGR V A+K IY+GV
Sbjct: 404 KIVIDGRRV---RSAEKTAKIYEGV 425
>pir||T46573 UDPglucose 6-dehydrogenase (EC 1.1.1.22) [validated] -
Sinorhizobium meliloti >gi|2959984|emb|CAA10918.1|
(AJ222661) UDP-glucose dehydrogenase [Sinorhizobium
meliloti]
Length = 437
Score = 178 bits (448), Expect = 8e-44
Identities = 137/441 (31%), Positives = 218/441 (49%), Gaps = 24/441 (5%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
I + G G +GL FAD G V+ VD +E ++++ G+ I E PGLD LV NV +
Sbjct: 3 ITMIGAGYVGLVSGVCFADFGHDVVCVDKDEGKISALKKGQIPIFE-PGLDHLVASNVAS 61
Query: 83 GRLKATTDGILAAKKADVMIILV--PTLADDRGNLKLESVYDVAEKISKGLEKGDIVITE 140
GRL T D A +DV+ I V P+ D G+ L VY A +I+ L+ +V+T+
Sbjct: 62 GRLNFTDDLKTAVAASDVVFIAVGTPSRRGD-GHADLSYVYAAAREIASNLQGFTVVVTK 120
Query: 141 ATMPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGA--SDERT 198
+T+P GT + + I+ ++ + D + PE G AI D ++G SD R
Sbjct: 121 STVPVGTGDEVERIIRETNPAV-DVTVVSNPEFLREGAAIEDFKRPDRIVIGVDGSDGRA 179
Query: 199 LEAVIGIYETIN-RKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIE 257
E + +Y + + + ++ + +E +K + + I NE+A CE+ G + +
Sbjct: 180 REVMTEVYRPLYLNQSPLVFTTRRTSELIKYAGNAFLAMKITFINEIADLCEKVGANVQD 239
Query: 258 IFNAANTQPYC---HLHMPGAGVGGHCIPIYPWFVINLAKK--TNVRLIRTAREINDSMP 312
+ LH G G GG C P ++ A+ T VRL+ T +ND+
Sbjct: 240 VARGIGLDGRIGSKFLHA-GPGYGGSCFPKDTLALVKTAQDHDTPVRLVETTVAVNDNRK 298
Query: 313 RHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYAYD 372
R + + A AG ++GSK VLGLTF+ + +PAI V++ L++ GA V YD
Sbjct: 299 RAMGRKVIAA---AGGDIRGSKYAVLGLTFKPNTDDMRDTPAIAVVQALQDAGARVTGYD 355
Query: 373 PLCTREDAERF--GAKWKED----FKDVDAIVIVTDHREFKTLDLKEIAAEVRTKVIVDG 426
P E+A + G D + DA+VI+T+ EF+ LD + + ++T ++VD
Sbjct: 356 PE-GMENARKLIEGLDCARDPYEAAAEADALVIITEWNEFRALDFDRLKSTMKTPLLVDL 414
Query: 427 RNVIHPEEAKKLGFIYKGVGR 447
RN+ +E K GF Y +GR
Sbjct: 415 RNIYRKDEVAKHGFRYASIGR 435
>pir||C82713 polysaccharide biosynthetic protein XF1183 [imported] - Xylella
fastidiosa (strain 9a5c)
>gi|9106151|gb|AAF83993.1|AE003952_4 (AE003952)
polysaccharide biosynthetic protein [Xylella fastidiosa]
Length = 433
Score = 175 bits (439), Expect = 9e-43
Identities = 144/432 (33%), Positives = 209/432 (48%), Gaps = 20/432 (4%)
Query: 15 AIKNGDVT---IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPG 71
A K G+ T IAV GLG +GLPLA F +G DI+ V + G + I E
Sbjct: 6 ADKQGEPTLARIAVVGLGYVGLPLAVAFGRQ-RPTLGFDIDICRVQQLCAGHD-ITCEIE 63
Query: 72 LDELVKKNVEAGRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGL 131
L+EL +A R + + II VPT D L + + ++ L
Sbjct: 64 LEEL-----QAARHLRYSSDPRELSDCQIFIITVPTPIDVAEQPDLGPLRSASMLVASVL 118
Query: 132 EKGDIVITEATMPPGTTESL-IPILEK-SGLKLG-DFGLAHAPERTMTGTAIRDITGQYP 188
+ GD+VI E+T+ PGTTE + +P+LE SGL DF ++PER G R +
Sbjct: 119 KPGDLVIYESTVYPGTTEEVCVPLLEVGSGLCFNVDFHCGYSPERINPGDRKRRLQ-DIC 177
Query: 189 KIVGASDERTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWC 248
KI+ S V +Y I G SI+ AEA KV E I RDVNIAL NELAL
Sbjct: 178 KIISGSTPDITAVVDALYSQIIVAGTWCAPSIRVAEAAKVVENIQRDVNIALVNELALIF 237
Query: 249 EEHGLDAIEIFNAANTQPYCHLHMPGAGVGGHCIPIYPWFVINLAKKTNV--RLIRTARE 306
G+D +++ AA T+ PG VGGHCI + P+++++ ++ LI TAR
Sbjct: 238 NRLGIDTLDVLEAAETKWNFLPFRPGL-VGGHCIGVDPYYLLHKSESVGYYPDLIHTARR 296
Query: 307 INDSMPRHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGA 366
+N + HVV+ V L + PM + +LVLG+TF+ + S A+D++R + GA
Sbjct: 297 VNSRVSWHVVDRVVALLGELSVPMTRAVVLVLGVTFKEDCPDLRNSRALDLVRMFRTLGA 356
Query: 367 EVYAYDPLCTREDA---ERFGAKWKEDFKDVDAIVIVTDHREFKTLDLKEIAAEVRTKVI 423
+V DP + A E + DAIV+ H +++ D+ IAA + + +
Sbjct: 357 QVDVCDPCADPQQALEHEAVTLCTEPKAGAYDAIVLAVAHAQYRMYDVATIAALGKPQAV 416
Query: 424 VDGRNVIHPEEA 435
V + P A
Sbjct: 417 VYDVKSVWPRAA 428
>pir||F82659 UDP-glucose dehydrogenase XF1606 [imported] - Xylella fastidiosa
(strain 9a5c) >gi|9106655|gb|AAF84415.1|AE003988_2
(AE003988) UDP-glucose dehydrogenase [Xylella
fastidiosa]
Length = 450
Score = 173 bits (433), Expect = 5e-42
Identities = 124/443 (27%), Positives = 210/443 (46%), Gaps = 19/443 (4%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
+A++G G +GL A+ G +V+ VDIN+ V+ +N G I E PGL+ +VK N
Sbjct: 3 VAIFGTGYVGLVTGTCLAEVGHEVLCVDINQAKVDGLNCGVIPIYE-PGLEPMVKANHAT 61
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITEAT 142
GRL+ TTD + A ++ I V T D+ G L+ V VA I + +++ IV+ ++T
Sbjct: 62 GRLRFTTDSVAAIAHGEITFIAVGTPPDEDGAADLQYVLAVARTIGQCIDRSTIVVNKST 121
Query: 143 MPPGTTESLIPILEKSGLKLG---DFGLAHAPERTMTGTAIRDITGQYPKIVGASDERTL 199
+P GT + + ++ G F + PE G A+ D ++GA +
Sbjct: 122 VPVGTADQVRAAIQHEMDVRGVDFKFEVVSNPEFLKEGDAVADCMRPDRIVIGARSRDAV 181
Query: 200 EAVIGIYETINRK-GVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIEI 258
+ +Y NR I +++AE K I+ NE+A E G D +
Sbjct: 182 VRMRRLYAPFNRNHDRIVEMDVRSAELTKYAANAMLATKISFMNEVANIAEYVGADIEYV 241
Query: 259 FNAANTQPYC--HLHMPGAGVGGHCIPIYPWFVINLAKKTNV--RLIRTAREINDSMPRH 314
+ P + PG G GG C P + A++ V +L+ ++N + H
Sbjct: 242 RKGIGSDPRIGWYFIYPGVGYGGSCFPKDVKALARTAQQYGVDPKLLNAVEDVNHAQKGH 301
Query: 315 VVELTVRALNDAGKP--MKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYAYD 372
+ EL +R +G+ + G V GL F+ + ++P+ ++ +L + GA+V AYD
Sbjct: 302 LFELMLRHYGCSGESTVLAGKTFAVWGLAFKPNTDDMREAPSCRLLVQLWKAGAQVRAYD 361
Query: 373 PLCTREDAERFGAKWKEDFKD--------VDAIVIVTDHREFKTLDLKEIAAEVRTKVIV 424
P +E FG + F + DA+++VT+ ++F++ D I ++ VI
Sbjct: 362 PEAMQEARRIFGERDDLVFCETAYAALQCADALIVVTEWKQFRSPDFFVIRDALKDAVIF 421
Query: 425 DGRNVIHPEEAKKLGFIYKGVGR 447
DGRN+ P+E ++ G Y G+GR
Sbjct: 422 DGRNLYDPQEIEEAGLAYYGIGR 444
>pir||H70301 nucleotide sugar dehydrogenase - Aquifex aeolicus
>gi|2982765|gb|AAC06391.1| (AE000669) nucleotide sugar
dehydrogenase [Aquifex aeolicus]
Length = 437
Score = 169 bits (425), Expect = 4e-41
Identities = 126/442 (28%), Positives = 221/442 (49%), Gaps = 25/442 (5%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
++V G G +GL AA F+ G +V+ V+ V + G++ I E PGL+EL+++ +
Sbjct: 3 LSVIGGGYVGLVTAACFSHLGHEVLVVEKIPEKVELLRRGKSPIYE-PGLEELLREGINE 61
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITEAT 142
GRL TTD + ++V+ I V T ++ G+ L V +VA +K ++ +++ ++T
Sbjct: 62 GRLSFTTDIKEGIEFSEVIFICVGTPSNPDGSADLSQVEEVARFTAKYMDSYKLLVNKST 121
Query: 143 MPPGTTESL---IPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASDERTL 199
+P GT + + + K+ K +F +A PE G A++D +VG ER
Sbjct: 122 VPVGTQRKVKRTVRLYLKN--KELEFDVASNPEFLREGHAVKDFLEPDRIVVGVESERAK 179
Query: 200 EAVIGIYETINRKGV-IPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIEI 258
E ++ IY+ I KG I +++ AE +K + I+ N ++ CE+ G + E+
Sbjct: 180 EVLLEIYKPITDKGFPILITNPPTAEIIKYASNTFLATKISFINMISDLCEKVGANVEEV 239
Query: 259 FNAANTQPYC--HLHMPGAGVGGHCIPIYPWFVINLAKKTNV--RLIRTAREINDSMPRH 314
G G GG C+P I + ++ V +++ A IN+S
Sbjct: 240 AQGMGYDKRIGKEFLRAGLGWGGSCLPKDTKAFIRILEELGVDATILKGALGINESR--- 296
Query: 315 VVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYAYDPL 374
V+ ++ L DA +KG I + GL+F+ + ++P++ V+ L GA++ AYDP
Sbjct: 297 -VDRLLQKLKDALWILKGKTIAIWGLSFKPNTDDIREAPSLKVVERLLREGAKIRAYDPK 355
Query: 375 CTR---------EDAERFGAKWKEDFKDVDAIVIVTDHREFKTLDLKEIAAEVRTKVIVD 425
T ED F K+K + +A++I+T+ EFK +L+ + + +I+D
Sbjct: 356 ATENFKRVFIEGEDLRYFDDKYKA-VEGAEALLILTEWDEFKRANLERVKRLMELPIIID 414
Query: 426 GRNVIHPEEAKKLGFIYKGVGR 447
GRN+ P+E + LGF Y +GR
Sbjct: 415 GRNIYDPQEVRNLGFEYYSMGR 436
>gb|AAF23790.1|AF213822_5 (AF213822) UDP-glucose dehydrogenase [Zymomonas mobilis]
Length = 437
Score = 167 bits (419), Expect = 2e-40
Identities = 132/438 (30%), Positives = 215/438 (48%), Gaps = 20/438 (4%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
I + G G +GL A F+D G VI VD ++ + + G I E PGL ++V NV+A
Sbjct: 3 ITMIGSGYVGLVSGACFSDIGHNVICVDHDQEKIALLQKGVMPIYE-PGLADMVANNVKA 61
Query: 83 GRLKATTDGILAAKKADVMIILV--PTLADDRGNLKLESVYDVAEKISKGLEKGDIVITE 140
GRL + D + K AD + I V P+ D G+ L V+ A++I+ + +V+ +
Sbjct: 62 GRLSFSNDLASSVKDADAVFIAVGTPSRRGD-GHADLSYVFAAAKEIAASVSDNTVVVDK 120
Query: 141 ATMPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASDERTLE 200
+T+P GT + + I+ + +A PE G AI D ++G + E
Sbjct: 121 STVPVGTGDEVERIIREIAPDK-KIWVASNPEFLREGAAIGDFKRPDRIVIGTENPEARE 179
Query: 201 AVIGIYETIN-RKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIEI- 258
+ IY + + I +S ++AE +K + I NE+A CE G D ++
Sbjct: 180 IMQEIYRPLYLNQSPILFTSRRSAELIKYASNAFLATKITFINEMADLCEAVGGDVQDVA 239
Query: 259 --FNAANTQPYCHLHMPGAGVGGHCIPIYPWFVINLAKK--TNVRLIRTAREINDSMPRH 314
A N LH G G GG C P ++ A+ T +R++ + N+ R
Sbjct: 240 RGIGADNRIGSKFLHA-GPGYGGSCFPKDTLALLKTAENFATPLRVVESVVTANNIRKRA 298
Query: 315 VVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYAYDPL 374
+ ++A+ GK M+G KI +LGL F+ + +P++ +I+ L++ GA ++AYDP
Sbjct: 299 MARKVLQAI---GKDMRGQKIGLLGLPFKPNTDDMRDAPSLALIQGLEDAGAIIHAYDPE 355
Query: 375 CTREDAERFGAKWKED-----FKDVDAIVIVTDHREFKTLDLKEIAAEVRTKVIVDGRNV 429
+ ED + +A+VIVT+ F+ LDLK IA ++T +++D RN+
Sbjct: 356 GMVQARPLLPNVIFEDEPYKVAEKAEALVIVTEWDAFRALDLKRIAGLLKTPLLLDLRNI 415
Query: 430 IHPEEAKKLGFIYKGVGR 447
EEAKK G +Y G+GR
Sbjct: 416 YTEEEAKKAGLVYHGIGR 433
>gb|AAG18685.1| (AE004973) UDP-glucose dehydrogenase; Ugd [Halobacterium sp. NRC-1]
Length = 430
Score = 166 bits (416), Expect = 5e-40
Identities = 132/441 (29%), Positives = 218/441 (48%), Gaps = 33/441 (7%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
+++ G G +G +AA F D G V+ VDI++ +V+++N G+ I EPGLD+L+ +
Sbjct: 3 VSIVGSGYVGTTVAACFTDMGHDVVNVDIDQDIVDAINAGKAPI-HEPGLDDLLATH--G 59
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGD---IVIT 139
G A T + DV + +PT + + G++ + AE + L + D +V+T
Sbjct: 60 GDTLAATTDYEDVLETDVTFLALPTPSKEDGSIDTSIIEAAAETLGDTLREKDGDHVVVT 119
Query: 140 EATM-PPGTTESLIPIL-EKSGLKLG-DFGLAHAPERTMTGTAIRDITGQYPKIVGASDE 196
++T+ P TTE+L PIL + SG +LG D +A PE GTA+ D + G+ E
Sbjct: 120 KSTVIPRTTTETLAPILADASGKQLGADLHVAMNPEFLREGTAVEDFQNPDKIVFGSDSE 179
Query: 197 RTLEAVIGIYETINRKG--VIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLD 254
++ + I++ + + + ++ AE +K + ++L N++ C+E G+D
Sbjct: 180 TAIDTLHEIFKPLIEASDATVVETGVEEAEMIKYANNAFLASKVSLINDIGNICKEFGVD 239
Query: 255 AIEIFNAANTQPYCHLHM--PGAGVGGHCIPIYPWFVINLAKKTNVR--LIRTAREINDS 310
A E+ +A G G GG C +I+ A +T ++ A +ND
Sbjct: 240 AYEVADAIGLDDRISERFLRSGLGWGGSCFGKDTNAIIHAATETGYEPAMLEAAVAVNDR 299
Query: 311 MPRHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYA 370
P ++ L L+D G ++ ++ VLGL F+ G + S AI VI L+E GA V A
Sbjct: 300 QPERLLSL----LDDHGD-VESERVAVLGLAFKPGTDDVRDSRAIPVINGLQERGANVAA 354
Query: 371 YDPLCTRE------DAERFGAKWKEDFKDVDAIVIVTDHREFKTLDLKEIAAEVRTKVIV 424
YDP+ D E A ++ D A V+ TD EF LD + A E T+V+V
Sbjct: 355 YDPVAAENMRTHFPDIEYTDAP-QDALADASACVVCTDWDEFAVLDDEFDAME--TRVVV 411
Query: 425 DGRNVIHPEEAKKLGFIYKGV 445
DGR +I ++ G Y+G+
Sbjct: 412 DGRRIIE----RRDGLTYEGL 428
>gb|AAD56735.1|AF125164_8 (AF125164) UDP-ManNAc dehydrogenase [Bacteroides fragilis]
Length = 408
Score = 165 bits (414), Expect = 8e-40
Identities = 118/387 (30%), Positives = 192/387 (49%), Gaps = 13/387 (3%)
Query: 27 GLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEAGRLK 86
GLG +GLP A + A +G KV GVDIN +VV N G+ HI E PG+ +++++ V G L
Sbjct: 7 GLGYIGLPTAIIAAKHGVKVTGVDINPKVVEMTNEGKLHIIE-PGMQDILEEVVANGMLT 65
Query: 87 ATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITEATMPPG 146
A+T ++ D ++VPT + V I L++GD+ + E+T P G
Sbjct: 66 ASTIPTVS----DAYFMVVPTPFKGNHEPDISYVEAATRAIIPFLKEGDLYVIESTSPVG 121
Query: 147 TTESLIPILEKSGLKLG-DFGLAHAPERTMTGTAIRDITGQYPKIVGASDERTLEAVIGI 205
TT + ++ +L +A+ PER + G I ++ +++G DER+ + I
Sbjct: 122 TTGKMADLIFSLRPELRCKIYIAYCPERVLPGNVIYELVHN-DRVIGGIDERSTDKAIEF 180
Query: 206 YETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIEIFNAANTQ 265
Y KG + + K AE K+ E RDV IA ANEL+L C++ G++ E+ + AN
Sbjct: 181 YSQFV-KGKLHKTDCKTAEMCKLTENSSRDVQIAFANELSLICDKAGINVWELIDLANKH 239
Query: 266 PYCHLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREINDSMPRHVVE-LTVRALN 324
P ++ P GVGGHCI + P+F I ++I AREIN+ E + L
Sbjct: 240 PRVNILQPSCGVGGHCIAVDPYF-ITADFPIESQIIAKAREINNYKAFWCAEKVENEMLK 298
Query: 325 DAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEW--GAEVYAYDPLCTREDAER 382
K + I ++GL F+ + + ++PA + ++ + A++ +P +
Sbjct: 299 FEIKYGRKPIIAMMGLAFKPDIDDLREAPAKYITTKVMQSCNNADILVVEPNVVEHKVFK 358
Query: 383 FGAKWKEDFKDVDAIVIVTDHREFKTL 409
+K+ + D IV + H FKTL
Sbjct: 359 L-TNYKDAYAKADIIVFLVAHSVFKTL 384
>emb|CAC05895.1| (AL391754) putative dehydrogenase [Streptomyces coelicolor]
Length = 443
Score = 164 bits (412), Expect = 1e-39
Identities = 118/358 (32%), Positives = 173/358 (47%), Gaps = 10/358 (2%)
Query: 22 TIAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVE 81
T+AV GLG +GLP A D GA VIGVD + + + G + L
Sbjct: 16 TVAVVGLGYVGLPTALALCDAGATVIGVDSSPERLRDIARGAVDLLP---LHHAQLACAS 72
Query: 82 AGRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITEA 141
AG T A + AD ++I VPT D R L ++ + + G +++ +
Sbjct: 73 AGDRFRLTPDATAVRDADAVVICVPTPVDARRRPDLAALSAACASVVEHAVPGQLIVLTS 132
Query: 142 TMPPGTTESL-IPILEKSGLKLG-DFGLAHAPERTMTGTAIRDITGQYPKIVGASDERTL 199
T GTT L + L GL + D +A APER G R + P++VG + R+
Sbjct: 133 TSYVGTTRDLLVEPLRARGLTVDEDVYVAFAPERIDPGNE-RHTPERTPRLVGGAGPRSS 191
Query: 200 EAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIEIF 259
A + V + + AE K++E YR VNIALANELA C GL +
Sbjct: 192 RAAADLLAP-TASAVRTVPDPETAEMAKLWENTYRAVNIALANELADACHSLGLAPAPVI 250
Query: 260 NAANTQPYCHLHM-PGAGVGGHCIPIYPWFVI-NLAK-KTNVRLIRTAREINDSMPRHVV 316
AA T+PY + PG GVGGHCIP P +++ L K + L+ TA N P +
Sbjct: 251 EAAATKPYGFMPFYPGPGVGGHCIPCDPHYLLWQLGKVRQQAPLVATALAANSRRPARIT 310
Query: 317 ELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYAYDPL 374
E + L D+ P G+++L++G+ ++ GV + +SPA++++ L E GA V DPL
Sbjct: 311 ERALDLLADSAVPAHGARVLLIGVAYKEGVADVRESPALEILAGLAEAGAHVAYCDPL 368
>gb|AAG26472.1|AF285774_12 (AF285774) putative UDP-glucose dehydrogenase [Bacteroides
fragilis]
Length = 440
Score = 162 bits (405), Expect = 9e-39
Identities = 121/439 (27%), Positives = 210/439 (47%), Gaps = 20/439 (4%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
IA+ G G +GL F++ G V VD+ E ++++ G I E PGL+++V +N A
Sbjct: 3 IAIVGTGYVGLVTGTCFSEMGVDVTCVDVIESKIDNLKKGIIPIYE-PGLEDMVHRNYNA 61
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITEAT 142
GRLK TT +V+ V T D+ G+ L+ V +VA I K + +V+T++T
Sbjct: 62 GRLKFTTSLASCLNDVEVVFSAVGTPPDEDGSADLKYVLEVARTIGKTMNHYVLVVTKST 121
Query: 143 MPPGTTESLIPI----LEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASDERT 198
+P GT + + L+K GL L +F +A PE G A+ D +VG ER
Sbjct: 122 VPVGTAQQVKATIRGELDKRGLNL-EFDVASNPEFLKEGDAVDDFMKPDRVVVGVESERA 180
Query: 199 LEAVIGIYETINRKGV-IPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHG--LDA 255
+ +Y+ + + I +AE +K I+ N++A CE G ++
Sbjct: 181 KSIMERLYKPFMMNNYRLIFTDIPSAEMIKYAANSMLATRISFMNDIANLCELVGANVNM 240
Query: 256 IEIFNAANTQPYCHLHMPGAGVGGHCIPIYPWFVINLAKKT--NVRLIRTAREINDSMPR 313
+ A+++ PG G GG C P +I A K ++R+++ E+N+S
Sbjct: 241 VRKGIGADSRIGSKFLYPGCGYGGSCFPKDVKALIKTADKNGYSMRVLKAVEEVNNSQKS 300
Query: 314 HVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYAYDP 373
+ +R + + G +I + GL+F+ + ++PA+ +I ++ G V AYDP
Sbjct: 301 ILFNKLIRYFDG---NLSGKRIALWGLSFKPETDDMREAPALVLIDKILSCGGLVKAYDP 357
Query: 374 LCTREDAERFG--AKWKEDF----KDVDAIVIVTDHREFKTLDLKEIAAEVRTKVIVDGR 427
+ E R G ++ D D DA+++VT+ +EF+ + + +I+DGR
Sbjct: 358 IAVEECKRRIGDSIEYANDMYDAVLDADALLLVTEWKEFRMPSWGVLKKTMNRALIIDGR 417
Query: 428 NVIHPEEAKKLGFIYKGVG 446
N+ +E + +G Y +G
Sbjct: 418 NIYDRQELQSVGVEYTCIG 436
>pir||B83202 probable nucleotide sugar dehydrogenase PA3559 [imported] -
Pseudomonas aeruginosa (strain PAO1)
>gi|9949711|gb|AAG06947.1|AE004776_10 (AE004776)
probable nucleotide sugar dehydrogenase [Pseudomonas
aeruginosa]
Length = 464
Score = 161 bits (402), Expect = 2e-38
Identities = 125/442 (28%), Positives = 209/442 (47%), Gaps = 22/442 (4%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
I+V+G G +GL AAV A+ G V+ +DI+ V + G I E PGLD L+++ +++
Sbjct: 3 ISVFGSGYVGLVQAAVLAEVGHDVLCMDIDRNKVERLAQGLASIYE-PGLDALLREGLDS 61
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITEAT 142
GRL+ ++D LA + V I V T + G L +V+ VA+ I++ K IV+ ++T
Sbjct: 62 GRLRFSSDARLAVEHGRVQFIAVGTPPGEDGAADLGAVFVVADAIAEHRRKPVIVVEKST 121
Query: 143 MPPGTTESLIPILEK----SGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASDERT 198
+P GT + L +E+ G +L +F + PE G+A+ D +VG +E
Sbjct: 122 VPVGTGDRLRAHIERRLEADGREL-EFEIVSNPEFLKEGSAVADCRRPDRIVVGCDNEEV 180
Query: 199 LEAVIGIYETINRK-GVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIE 257
+ + +YE NR + +++AE K I+ N++A E G D
Sbjct: 181 RQVMRELYEPFNRNHDRMLFMGLRSAELTKYAANGMLATKISFINQIAELAEHLGADIEA 240
Query: 258 IFNAANTQPYCHLHM--PGAGVGGHCIPIYPWFVINLAKKTNVR--LIRTAREINDSMPR 313
+ P H PG G GG C P +I+ A++ + L++ IN +
Sbjct: 241 VRQGIGADPRIGYHFIYPGCGYGGSCFPKDMRALIHSAEQAHCSSDLLQAVEAIN-RRQK 299
Query: 314 HVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYAYDP 373
H + +R D ++G + GL F+ + +P+ +++ L GA+V AYDP
Sbjct: 300 HKLFERIRVFYDG--DLRGKTFALWGLAFKPNTDDMRDAPSRELMEALWRHGAQVRAYDP 357
Query: 374 LCTREDAERFG--------AKWKEDFKDVDAIVIVTDHREFKTLDLKEIAAEVRTKVIVD 425
+E +G + DA+VI T+ ++FK D + + ++ VI D
Sbjct: 358 EAMQETQRLYGHDERLSLMGTPEATLGGADALVICTEWQQFKAPDFELLKERLKAPVIFD 417
Query: 426 GRNVIHPEEAKKLGFIYKGVGR 447
GRN+ PE + GF Y +GR
Sbjct: 418 GRNLYDPERMARHGFHYYPMGR 439
>sp|O05973|UDG_RICPR UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|7431391|pir||E71638 UDP-glucose
6-dehydrogenase (udg) RP779 - Rickettsia prowazekii
>gi|2073510|emb|CAA72478.1| (Y11785) UDP-glucose
dehydrogenase [Rickettsia prowazekii]
>gi|3861306|emb|CAA15205.1| (AJ235273) UDP-GLUCOSE
6-DEHYDROGENASE (udg) [Rickettsia prowazekii]
Length = 434
Score = 159 bits (398), Expect = 6e-38
Identities = 123/439 (28%), Positives = 212/439 (48%), Gaps = 21/439 (4%)
Query: 21 VTIAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNV 80
+ I G G +GL + G V +D ++ ++ +N I E LDE +K +
Sbjct: 1 MNITFIGSGYVGLVSGIIMGYLGHNVTCLDNDDVKISKLNKKILPIYEAK-LDEYLKHAL 59
Query: 81 EAGRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITE 140
E+ RLK T + D + I V T + + G L+ VYD +K+SK + K +++ +
Sbjct: 60 ESDRLKFTNIYSNEFRNFDAIFITVGTPSKELGEADLKYVYDAVDKVSKHINKDCLIVIK 119
Query: 141 ATMPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASDERTLE 200
+T+PPG+ ++I L+ G F +A PE G+A+ D +VG +++ +
Sbjct: 120 STVPPGSCNNIIAYLKAKGF---SFNVASNPEFLREGSAVEDFLYPDRIVVGVNNKESEA 176
Query: 201 AVIGIYETINRKGV-IPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIEIF 259
+ IY + +G ++++ +E +K + IA NE+A CE+ G + ++
Sbjct: 177 LLRKIYAPLIEQGAKFLVTNLVTSELIKYVSNSFLATKIAFINEMADLCEKIGANIKDLS 236
Query: 260 NAANTQPYCHLHM--PGAGVGGHCIPIYPWFVINLAK--KTNVRLIRTAREINDSMPRHV 315
+ G G GG C P + NL + K + +++++ + N P ++
Sbjct: 237 QGVGLDQRIGRNFLNAGPGFGGSCFPKDILALNNLVENHKIDCKILKSVIKSNKLRPSNM 296
Query: 316 VELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYAYDPLC 375
V L+ +KG I +LGLT++ G + SPAI++I L V A+DP+
Sbjct: 297 VAKIATLLDG---DLKGRNIAILGLTYKAGTDDVRASPAIEIITILLNKDVYVKAFDPI- 352
Query: 376 TREDAER--------FGAKWKEDFKDVDAIVIVTDHREFKTLDLKEIAAEVRTKVIVDGR 427
E+A++ + A E K VD IVI T+ EFK L+ +EI V++ +I+D R
Sbjct: 353 GLENAKKNLEHKNLLYFASAVEACKSVDIIVIATEWSEFKELNWQEIYNLVKSPMIIDLR 412
Query: 428 NVIHPEEAKKLGFIYKGVG 446
N++ E KK+GF Y VG
Sbjct: 413 NILDNEVMKKIGFRYYAVG 431
>pir||A70067 NDP-sugar dehydrogenase homolog ywqF - Bacillus subtilis
>gi|1894744|emb|CAB07444.1| (Z92952) product similar to
Pseudomonas aeruginosa GDP-mannose 6-dehydrogenase
protein [Bacillus subtilis] >gi|2636148|emb|CAB15640.1|
(Z99122) similar to NDP-sugar dehydrogenase [Bacillus
subtilis]
Length = 440
Score = 158 bits (396), Expect = 1e-37
Identities = 120/439 (27%), Positives = 210/439 (47%), Gaps = 21/439 (4%)
Query: 21 VTIAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNV 80
+ I V G G +GL ++ G V +DI+ ++ + G + I E PGL+EL++KN
Sbjct: 1 MNITVIGTGYVGLVTGVSLSEIGHHVTCIDIDAHKIDEMRKGISPIFE-PGLEELMRKNT 59
Query: 81 EAGRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITE 140
GRL T +AD++ I V T G+ LE + D A++I+K +++ +V+T+
Sbjct: 60 ADGRLNFETSYEKGLAQADIIFIAVGTPQKSDGHANLEQITDAAKRIAKHVKRDTVVVTK 119
Query: 141 ATMPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASDERTLE 200
+T+P GT + + ++ + + +A PE G+AI D ++G +DE+T
Sbjct: 120 STVPVGTNDLINGLITEHLAEPVSISVASNPEFLREGSAIYDTFHGDRIVIGTADEKTAN 179
Query: 201 AVIGIYETINRKGVIPM--SSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLD--AI 256
+ E + R IP+ + I++AE +K + I+ NE++ CE+ G D A+
Sbjct: 180 TL----EELFRPFQIPIYQTDIRSAEMIKYASNAFLATKISFINEISNICEKVGADIEAV 235
Query: 257 EIFNAANTQPYCHLHMPGAGVGGHCIPIYPWFVINLAKKT--NVRLIRTAREINDSMPRH 314
+ + G G GG C P ++ +A + L+++ ++N++
Sbjct: 236 AYGMGQDKRIGSQFLKAGIGYGGSCFPKDTNALVQIAGNVEHDFELLKSVIKVNNNQQAM 295
Query: 315 VVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYAYDPL 374
+V+ +ALN G + G I +LGL+F+ + ++P+I + L A + AYDP+
Sbjct: 296 LVD---KALNRLG-GVTGKTIALLGLSFKPNTDDMREAPSIVIADRLAALDARIRAYDPI 351
Query: 375 CTRE------DAERFGAKWKEDFKDVDAIVIVTDHREFKTLDLKEIAAEVRTKVIVDGRN 428
A + +E K DA++I+TD + K L + T +I DGRN
Sbjct: 352 AVSHAKHVLPQAVEYKETIEEAVKGSDAVMILTDWADIKQFPLAAYQDLMETPLIFDGRN 411
Query: 429 VIHPEEAKKLGFIYKGVGR 447
+EA G Y VGR
Sbjct: 412 CYTLDEALAAGVEYYSVGR 430
>emb|CAB82012.1| (AL161755) putative nucleotide-sugar dehydrogenase [Streptomyces
coelicolor A3(2)]
Length = 405
Score = 157 bits (394), Expect = 2e-37
Identities = 126/428 (29%), Positives = 204/428 (47%), Gaps = 39/428 (9%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
+AV GLG GLPLA G +G +P V++ +
Sbjct: 5 LAVIGLGPYGLPLAQAAVAAGIPTLGYRTGPEA-------------DPLTPAEVRRMLAT 51
Query: 83 G-RLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITEA 141
G R G + +I PT G L L V A ++ + VI E+
Sbjct: 52 GFRTPTGPAGPAELGRVRTAVICAPTPPGADGGLDLTQVEAAARTLAAHMRPHTTVILES 111
Query: 142 TMPPGTTESLI-PILEK-SGLKLG-DFGLAHAPERTMTGTAIRDIT-GQYPKIVGASDER 197
+ PGTTE + P+LE+ SGL+ G DF LA++P R G RD T PK++G
Sbjct: 112 PVRPGTTEDFLRPLLEQGSGLRAGRDFHLAYSPSRVDPGN--RDFTPANTPKVIGGLTPA 169
Query: 198 TLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIE 257
E+ Y + K V+ + AE V++ E +R VNIAL NE+A+ C++ G+D +
Sbjct: 170 CTESAAAFYSRLTDK-VVRARGPREAETVQLLETNFRHVNIALVNEMAVLCDDLGVDLWD 228
Query: 258 IFNAANTQPY-CHLHMPGAGVGGHCIPIYPWFVINLAKKT--NVRLIRTAREINDSMPRH 314
+ A T+P+ H PG GVGGH + +L + ++R++ A+++N MPR+
Sbjct: 229 VLRCAETKPFGFHAFRPGPGVGGHSV------AQDLTGRAPHSLRMVELAQQVNAQMPRY 282
Query: 315 VVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYAYDP- 373
VV+ LN+ GK +G++IL+LG+T++ + + +PA ++ L GA V +DP
Sbjct: 283 VVQRAAALLNEHGKSARGARILLLGVTYKADLADQQATPAEEIATRLMSMGAAVSYHDPH 342
Query: 374 LCTREDAER---FGAKWKEDFKDVDAIVIVTDHREFKTLDLKEIAAEVRTKVIVDGRNVI 430
+ + A+R E D D +++ HR T DL+ ++ V+ ++++D R
Sbjct: 343 IPSWNVADRPVPRADSLYEAAADADLTILLQQHR---TYDLQGLS--VKAQLLLDTRGAT 397
Query: 431 HPEEAKKL 438
A +L
Sbjct: 398 PTGAAHRL 405
>pir||G69988 NDP-sugar dehydrogenase homolog ytcA - Bacillus subtilis
>gi|2293289|gb|AAC00367.1| (AF008220) YtcA [Bacillus
subtilis] >gi|2635570|emb|CAB15064.1| (Z99119) similar
to NDP-sugar dehydrogenase [Bacillus subtilis]
Length = 428
Score = 157 bits (394), Expect = 2e-37
Identities = 116/435 (26%), Positives = 203/435 (46%), Gaps = 20/435 (4%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
I V G G +GL L+A A G +I D + + + + G E PGL + + +
Sbjct: 3 ICVVGAGYVGLTLSAALASIGHDMICTDKDVKKIGQLKKGVIPFYE-PGLSDAI---LRC 58
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITEAT 142
G L +++ + ++ V+ I V T G+ +++ V +S+ + +IT++T
Sbjct: 59 GNLSFSSEVKSSMEECPVIFIAVGTPPRSDGSADTKALQSVIGDLSEAIRSYKTIITKST 118
Query: 143 MPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASDERTLEAV 202
+PPGT E++ L SG+ F + PE G A+ D+ ++G +E + A
Sbjct: 119 VPPGTNENIAKQLIASGVSKNLFNIVSNPEFLREGNALYDMLHPDKTVIGVQEEDHVSAA 178
Query: 203 I--GIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIEIFN 260
I IY+ I+ ++ +S+ AE +K + I+ NE+A CE + D +I
Sbjct: 179 IVKSIYKHIDTPFIV--TSLAGAELIKYANNFFLAAKISFINEMARICEAYQSDISDISR 236
Query: 261 AANTQPYC--HLHMPGAGVGGHCIP--IYPWFVINLAKKTNVRLIRTAREINDSMPRHVV 316
A P H G G GG C P + K T L+R + IND+ +
Sbjct: 237 AIGLDPRIGKHFLQAGIGYGGSCFPKDLQALQFAAQEKNTETFLLRAVQHINDTQ----L 292
Query: 317 ELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYAYDP-LC 375
L ++ + + ++G K VLG++F+ + S A+ ++ L E G +V+AYDP
Sbjct: 293 GLYIKKIQSFFETLQGKKAAVLGISFKPNTDDIRNSQAVRLMERLAELGCDVHAYDPEAV 352
Query: 376 TREDAERFGAKWKEDF---KDVDAIVIVTDHREFKTLDLKEIAAEVRTKVIVDGRNVIHP 432
E + + + F ++ D + + T+ EF D K+ A ++ ++++DGRNV+
Sbjct: 353 LPEHLRQHVTQHSQAFDAIEESDFLFLATEWSEFLAFDWKKAADIMKGRLVIDGRNVLKK 412
Query: 433 EEAKKLGFIYKGVGR 447
E + G I GVGR
Sbjct: 413 ELIEACGLICTGVGR 427
>pir||S74698 UDP-glucose dehydrogenase - Synechocystis sp. (strain PCC 6803)
>gi|1651923|dbj|BAA16849.1| (D90901) UDP-glucose
dehydrogenase [Synechocystis sp.]
Length = 453
Score = 157 bits (393), Expect = 2e-37
Identities = 127/455 (27%), Positives = 217/455 (46%), Gaps = 35/455 (7%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
+ V G G +GL A G +VI VD NE V + G++ I E PGL EL+ N+E+
Sbjct: 3 VCVIGTGYVGLVTGVCLAHIGHQVICVDNNEEKVKLMRAGQSPIYE-PGLSELMVANMES 61
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGL-EKGDIVITEA 141
GRL TTD +++ ++ I V T A + G+ V VA I + L E+ +++ ++
Sbjct: 62 GRLVFTTDLGKGVQESAILFIAVGTPALEDGSSDTRYVEAVARSIGEHLDEQYRVIVNKS 121
Query: 142 TMPPGTTESLIPIL--------EKSGLKLG-DFGLAHAPERTMTGTAIRDITGQYPKIVG 192
T+P G+ + + I+ +++G + +F + PE G+A+ D ++G
Sbjct: 122 TVPIGSGDWVRMIVTEGNEAHQQQTGQAIAVNFDVVSNPEFLREGSAVYDTFNPDRIVLG 181
Query: 193 ASDERTLEAVIGIYETINRKGV----------IPMSSIKAAEAVKVFEGIYRDVNIALAN 242
++ + L + +Y + + V + M+ + +AE +K + I+ N
Sbjct: 182 GNNPQALALMRELYTPLIERRVGENPELPPVPVVMTDLSSAEMIKYAANAFLATKISFIN 241
Query: 243 ELALWCEEHGLDAIEIFNAANTQPYCHLHMPGAGVG--GHCIPIYPWFVINLAKKTN--V 298
E+A C+ G D ++ AG+G G C P +I+ AK
Sbjct: 242 EVANICDRVGADVTQVAQGIGLDSRIGSKFLNAGIGWGGSCFPKDVSALIHTAKDYGYTT 301
Query: 299 RLIRTAREINDSMPRHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVI 358
++ E+N VVE + L K +KG I +LGLTF+ + +PA+++I
Sbjct: 302 SILNAVVEVNQVQRLIVVEKLQQEL----KILKGKVIGLLGLTFKPDTDDMRDAPALNII 357
Query: 359 RELKEWGAEVYAYDPLCTREDAER--FGAKWKED----FKDVDAIVIVTDHREFKTLDLK 412
++L GA+V AYDP+ ++ G K + DA+++VT+ +EF LD
Sbjct: 358 QQLNRLGAKVKAYDPIVSQSGVSHGLSGVKIESTPAMLADQCDALILVTEWQEFLKLDFP 417
Query: 413 EIAAEVRTKVIVDGRNVIHPEEAKKLGFIYKGVGR 447
+A+ + VI+DGRN + E+ + GF Y GVGR
Sbjct: 418 VLASRMHQAVIIDGRNFLDKEKLQGAGFRYLGVGR 452
>emb|CAA72087.1| (Y11203) UDP-glucose dehydrogenase [Acetobacter xylinus]
Length = 449
Score = 155 bits (387), Expect = 1e-36
Identities = 130/445 (29%), Positives = 214/445 (47%), Gaps = 27/445 (6%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
IA+ G G +GL FA+ G V V+ N + ++ G I E PGLD LV++NVEA
Sbjct: 3 IAMIGGGYVGLVSGTCFAEFGTDVAIVETNPDRLTALREGRIPIYE-PGLDRLVEENVEA 61
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGNLKLES--VYDVAEKISKGLEKGDIVITE 140
GRL D A K AD + + V T RG+ + ++ VY E+I++ + +++T+
Sbjct: 62 GRLTFGDDIAAAVKGADAVFVAVGT-PSRRGDGQADTSYVYAAVEQIARVADGYTVIVTK 120
Query: 141 ATMPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASD----- 195
+T+P GT + I+ K+ L DF +A PE G AI+D I+G
Sbjct: 121 STVPVGTGREIAQIIRKTRPDL-DFDVASNPEFLREGNAIQDFMRPDRVIIGTDQYKPEG 179
Query: 196 -ERTLEAVIGIYETINR-KGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGL 253
ER + +Y + + I + ++ AE +K + + I NE++ CE+ G
Sbjct: 180 TERAQNILRKLYRPLYLLETPIVFTGLETAELIKYSANSFLAMKITFINEISDLCEKVGA 239
Query: 254 DAIEIFNAANTQPYC---HLHMPGAGVGGHCIPIYPWFVINLAKKTN--VRLIRTAREIN 308
+ ++ + LH P G GG C P + + + VRLI T +N
Sbjct: 240 NVNDVARSIGLDGRIGKKFLH-PSPGFGGSCFPKDTRALTAIGRNAGSPVRLIETTVAVN 298
Query: 309 DSMPRHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEV 368
+ + + E R + AG + G I VLGLTF+ + ++ +I V+ L + GA++
Sbjct: 299 EQRMKDMGE---RVITFAGGDVSGLTIGVLGLTFKPETDDMREAASIPVLDMLDKGGAKI 355
Query: 369 YAYDP--LCTREDAERFGAKWKEDFKDV----DAIVIVTDHREFKTLDLKEIAAEVRTKV 422
A+DP + T + D D D +V++T+ EF++L +++AAE++ +
Sbjct: 356 RAFDPAGMTTARPVLPQSVTYCTDALDAAKGADILVVLTEWNEFRSLAPEKLAAEMKGRK 415
Query: 423 IVDGRNVIHPEEAKKLGFIYKGVGR 447
I D RN+ P+ K GF Y +GR
Sbjct: 416 IADLRNIWDPKAIKDAGFEYISLGR 440
>gb|AAG19454.1| (AE005038) UDP-glucose dehydrogenase; Udg1 [Halobacterium sp.
NRC-1]
Length = 426
Score = 152 bits (380), Expect = 8e-36
Identities = 123/429 (28%), Positives = 206/429 (47%), Gaps = 33/429 (7%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
+++ G G +G +AA FA+ G V+ VD++ VV ++N+G+ I EPGL E + + A
Sbjct: 3 VSIVGSGYVGTTIAACFAELGHTVVNVDVDADVVAAINDGDAPI-HEPGLAERI--DAHA 59
Query: 83 G-RLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGD--IVIT 139
G RL+ATTD A + DV + +PT A + G++ + A + + L D +V+
Sbjct: 60 GTRLRATTD-YEAVRDTDVTFLALPTPAREDGSIDTSIMESGAASLGEALAGADDHMVVV 118
Query: 140 EATMPPGTTESLIPILEKSGLKLGDFG---LAHAPERTMTGTAIRDITGQYPKIVGASDE 196
++T+ PGTTE ++ +S L F LA PE G+A+ D + GA +
Sbjct: 119 KSTVVPGTTEDVV----ESALVSAGFDDPLLAMNPEFLRMGSAVDDFRHPDKVVFGARRD 174
Query: 197 RTLEAVIGIYETINRKG---VIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGL 253
+ + ++E + + + ++ AE +K + ++L N+L C+E G+
Sbjct: 175 AAYDQLHAVFEPLLADAGDATVVETGLREAEMIKYANNAFLASKVSLINDLGNICKELGV 234
Query: 254 DAIEIFNAANTQPYC--HLHMPGAGVGGHCIPIYPWFVINLAKKTNVR--LIRTAREIND 309
DA E+ +A G G GG C P + AK ++ A E+ND
Sbjct: 235 DAYEVADAIAEDDRISGRFLRSGVGWGGSCFPKDVAAITAAAKDAGYEPAMLEAAVEVND 294
Query: 310 SMPRHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVY 369
P ++ L D + G ++ VLGL+F+ G + + A+ VI L++ A+V
Sbjct: 295 RQPERLLSLL-----DGHVDVAGERVAVLGLSFKPGTDDIRGTRAVPVIDGLQDREADVV 349
Query: 370 AYDPLCTREDAER-----FGAKWKEDFKDVDAIVIVTDHREFKTLDLKEIAAEVRTKVIV 424
AYDP+ + AE+ + D V+VTD EF LD + A + +V+V
Sbjct: 350 AYDPVAAEKMAEQRPEVTYADSAAGALADAVGAVVVTDWDEFAALDDEFDA--MAERVVV 407
Query: 425 DGRNVIHPE 433
DGR V+ P+
Sbjct: 408 DGRRVVDPQ 416
>emb|CAA11569.1| (AJ223832) hypothetical protein [Mycobacterium avium subsp.
silvaticum]
Length = 411
Score = 149 bits (373), Expect = 5e-35
Identities = 99/386 (25%), Positives = 184/386 (47%), Gaps = 13/386 (3%)
Query: 74 ELVKKNVEAGRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEK 133
EL+ +N E G + TTD + ADV+ I VPT + G L V+ VA+ I +++
Sbjct: 28 ELIARNRENGLIDFTTDRQRGIEHADVIFIAVPTPMGESGAADLTYVFSVADDIGSYIDR 87
Query: 134 GDIVITEATMPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGA 193
+++ ++T+P GT + + I+ + +F + PE G AI D ++G+
Sbjct: 88 YKVIVDKSTVPVGTADQITAIIRSKTDQ--EFDVVSNPEFLKQGKAIADFMQPDRVVIGS 145
Query: 194 SDERTLEAVIGIYETINRK-GVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHG 252
+R L + +YE R + +++AE K + I+ NE++ CE+ G
Sbjct: 146 DSKRALRIMEELYEPFLRTFHPLIAIDVRSAEMAKYAANCFLATKISFINEMSNLCEKAG 205
Query: 253 LDAIEIFNA--ANTQPYCHLHMPGAGVGGHCIPIYPWFVINLAK--KTNVRLIRTAREIN 308
D + A A+ + PG G GG C+P ++ A +++ L+R +N
Sbjct: 206 ADISAVREAIGADKRIGYDFLFPGIGYGGSCLPKDVRALLYTADCLGSDMHLLRAVERVN 265
Query: 309 DSMPRHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEV 368
D +V + + K + G +I + GL+F+ + +P++ + +L E+GA V
Sbjct: 266 DEQKAALVSKIITRFGGSEKNLDGLRIGLWGLSFKPQTDDVRAAPSLVIAEKLVEFGATV 325
Query: 369 YAYDPLCTRE------DAERFGAKWKEDFKDVDAIVIVTDHREFKTLDLKEIAAEVRTKV 422
A+DP + D+ + + + DA++++T+ ++F+ + + +R V
Sbjct: 326 CAFDPEAMEQTKKVLGDSIEYAGNMYDAVQGADALLLLTEWKQFQRPSWSRVRSAMRGCV 385
Query: 423 IVDGRNVIHPEEAKKLGFIYKGVGRV 448
+ DGRN+ PE K GF Y G+GR+
Sbjct: 386 VFDGRNIYDPERMKDEGFEYYGMGRI 411
>pir||H83393 probable nucleotide sugar dehydrogenase PA2022 [imported] -
Pseudomonas aeruginosa (strain PAO1)
>gi|9948026|gb|AAG05410.1|AE004628_8 (AE004628) probable
nucleotide sugar dehydrogenase [Pseudomonas aeruginosa]
Length = 453
Score = 147 bits (368), Expect = 2e-34
Identities = 122/445 (27%), Positives = 208/445 (46%), Gaps = 25/445 (5%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
+ V G G +GL AA FA+ G +V V+ + V + GE I E PGL+ +++ ++A
Sbjct: 3 LCVIGAGYVGLVTAACFAEMGNQVRCVERDRERVARLRRGEMPIYE-PGLESILRDQLDA 61
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITEAT 142
RL T A+V+ I V T + G+ L V VAE++ L + IV+ ++T
Sbjct: 62 ARLTFTASLAEGLADAEVVFIAVGTPCGEDGSADLSHVLAVAEQLGAQLRQACIVVNKST 121
Query: 143 MPPGTTESLIPILEKSGL----KLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASDERT 198
+P GT E + I+ + GL K +A PE G+A+ D I+G+++ +
Sbjct: 122 VPVGTAERVEEII-RLGLARRRKRFRVAVASNPEFLKEGSAVDDFRRPDRVIIGSAETQA 180
Query: 199 LEAVIGIYETI--NRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAI 256
E + +Y N + V+ M + AE K + I+ NE+A C G+D
Sbjct: 181 GETLRQLYAPFLRNHERVLLMGR-REAEFSKYAANAFLATKISFMNEMAGLCALTGVDIE 239
Query: 257 EIFNAANTQPYCHLHM--PGAGVGGHCIPIYPWFVINLAKKTNV-RLIRTAREINDSMPR 313
++ + H G G GG C P +I A++ I A E ++ +
Sbjct: 240 DVRRGMGSDKRIGTHFIYAGCGYGGSCFPKDVRALIRSAEQQGYDSQILRAVEARNARQK 299
Query: 314 HVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYAYDP 373
++ T+ L +G + + GL F+ G + ++P++ ++ L G V A+DP
Sbjct: 300 ELLFETLGELFQGR--WQGRTVALWGLAFKPGTDDLREAPSLVLLEALLRHGVRVRAHDP 357
Query: 374 LCTREDAERFGAKWK-----------EDFKDVDAIVIVTDHREFKTLDLKEIAAEVRTKV 422
+ A R+ + DA+V+VT+ ++F+ D ++I +RT +
Sbjct: 358 VANAGVAARYPEAVACARLTLHDSPYAAVEGADALVLVTEWKQFRQPDFQKIRGSMRTPL 417
Query: 423 IVDGRNVIHPEEAKKLGFIYKGVGR 447
+VDGRN+ P +LGFIY+G+GR
Sbjct: 418 LVDGRNLYAPARMAELGFIYQGIGR 442
>gb|AAK41109.1| UDP-glucose 6-dehydrogenase (ugd) [Sulfolobus solfataricus]
Length = 409
Score = 146 bits (364), Expect = 6e-34
Identities = 127/433 (29%), Positives = 206/433 (47%), Gaps = 34/433 (7%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
I V GLG +GL AV AD G +V+GVDI++ V + + I EPGLDEL+ KN
Sbjct: 3 IGVVGLGVVGLVTGAVLADQGHEVVGVDIDQNKVKGLQCNRSPI-YEPGLDELLLKN--K 59
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITEAT 142
R TTD A K D++ I V T + G + V D A+ + L++ IV+ ++T
Sbjct: 60 NRFLFTTD-YSALKDVDIVFITVATPTVE-GKNYIGYVLDAAKTMKPYLKRDAIVVVKST 117
Query: 143 MPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASDERTLEAV 202
+ PGT+ + I+E+ + PE G+A+ D T + +IV SD + V
Sbjct: 118 VVPGTSRKVKQIVERE--------VVANPEFLKEGSAVID-TIKPDRIVIGSDSKAAGDV 168
Query: 203 IGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEE-HGLDAIEIFNA 261
I + K V+ +SI+ AE +K + I+ NE+A CE D I A
Sbjct: 169 IENLWSFT-KTVVLRTSIEEAEMIKYAANSFLATKISFINEIANLCEVIPNCDVNTIAKA 227
Query: 262 ANTQ----PYCHLHMPGAGVGGHCIPIYPWFVINLAKK--TNVRLIRTAREINDSMPRHV 315
PY G G GG C P + A++ ++++ A ++N+ PR
Sbjct: 228 IGLDKRIAPY--FLNAGLGYGGSCFPKDTLAFASFARELGEELKIVEAAIKVNEERPRRA 285
Query: 316 VELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYAYDPLC 375
V++ L + +KG I +LG+ F+ + +S A+ + + L + GA V AYDP
Sbjct: 286 VKIMEELLGE----LKGKTICILGIAFKPNTDDTRESVALKIAKLLVDIGANVIAYDPKA 341
Query: 376 TREDAERFGAKWKEDFKDVDAIVIVTDHREFKTLDLKEIAAEVRTKVIVDGRNVIHPEEA 435
E +K +E K D ++I T+ EF+ ++ ++ K ++DGR V+ P +
Sbjct: 342 KTSLVEMVSSK-EECVKRSDGVIIATEWDEFRGIE-----HMLKDKAVLDGRRVLDPNKM 395
Query: 436 KKLGFIYKGVGRV 448
+ + G+ +V
Sbjct: 396 SRSKYRAIGLSKV 408
>gb|AAD43344.1|AF159428_1 (AF159428) putative UDP-glucose dehydrogenase [Burkholderia
pseudomallei]
Length = 466
Score = 146 bits (364), Expect = 6e-34
Identities = 115/458 (25%), Positives = 201/458 (43%), Gaps = 38/458 (8%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
I + G G +GL A A+ G V +D++ R ++ +NNG I EPGL E++ + A
Sbjct: 3 ITIIGTGYVGLVTGACLAEIGHDVFCLDVDPRKIDILNNGGMPI-HEPGLQEIIARTRAA 61
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITEAT 142
GR+ +TD + ++ I V T D+ G+ L+ V + A I + + +++ ++T
Sbjct: 62 GRIAFSTDIEASVAHGEIQFIAVGTPPDEDGSADLQYVLEAARNIGRHMTGYKVIVDKST 121
Query: 143 MPPGTTESLIPILEK-------SGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASD 195
+P GT + + ++++ +G F + PE G A+ D I+G D
Sbjct: 122 VPVGTAQRVRAVIDEALAARGLAGSAEHRFSVVSNPEFLKEGAAVDDFMRPDRIIIGVDD 181
Query: 196 ER----TLEAVIGIYETINRKGVIPM-SSIKAAEAVKVFEGIYRDVNIALANELALWCEE 250
+ E + +Y NR + +++AE K I+ NE++ +
Sbjct: 182 DAAGAIAREKMKKLYAPFNRNHERTIYMDVRSAEFSKYAANAMLATRISFMNEMSNLADR 241
Query: 251 HGLDAIEIFNAANTQPYCHLHM--PGAGVGGHCIPIYPWFVINLAKKTN--VRLIRTARE 306
G D + + P H G G GG C P +I A + +R++ +
Sbjct: 242 VGADIEALRRGIGSDPRIGYHFLYAGVGYGGSCFPKDVQALIRTASENGQPLRILEAVED 301
Query: 307 INDSMPRHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGA 366
+N + +++ + G + G V GL F+ + ++P+ +I L GA
Sbjct: 302 VNHAQKNVLLDKIEKRY---GADLAGRTFAVWGLAFKPNTDDMREAPSRRLIASLLARGA 358
Query: 367 EVYAYDPLCTREDAERFGAKWKEDFKD-----------------VDAIVIVTDHREFKTL 409
V AYDP+ ++A R A D D DA+VIVT+ +EFK+
Sbjct: 359 MVRAYDPVAL-DEARRVFALDLHDGADALARLAFVDSADDALAGADALVIVTEWKEFKSP 417
Query: 410 DLKEIAAEVRTKVIVDGRNVIHPEEAKKLGFIYKGVGR 447
D + + ++ VI DGRN+ P+ +LG Y +GR
Sbjct: 418 DFAHLKSVLKAPVIFDGRNLYEPDAMAELGIDYHAIGR 455
>emb|CAB57493.1| (Y18930) udp-glucose dehydrogenase [Sulfolobus solfataricus]
Length = 409
Score = 146 bits (364), Expect = 6e-34
Identities = 127/433 (29%), Positives = 206/433 (47%), Gaps = 34/433 (7%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
I V GLG +GL AV AD G +V+GVDI++ V + + I EPGLDEL+ KN
Sbjct: 3 IGVVGLGVVGLVTGAVLADQGHEVVGVDIDQNKVKGLQCNRSPI-YEPGLDELLLKN--K 59
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITEAT 142
R TTD A K D++ I V T + G + V D A+ + L++ IV+ ++T
Sbjct: 60 NRFLFTTD-YSALKDVDIVFITVATPTVE-GKNYIGYVLDAAKTMKPYLKRDAIVVVKST 117
Query: 143 MPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASDERTLEAV 202
+ PGT+ + I+E+ + PE G+A+ D T + +IV SD + V
Sbjct: 118 VVPGTSRKVKQIVERE--------VVANPEFLKEGSAVID-TIKPDRIVIGSDSKAAGDV 168
Query: 203 IGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEE-HGLDAIEIFNA 261
I + K V+ +SI+ AE +K + I+ NE+A CE D I A
Sbjct: 169 IENLWSFT-KTVVLRTSIEEAEMIKYAANSFLATKISFINEIANLCEVIPNCDVNTIAKA 227
Query: 262 ANTQ----PYCHLHMPGAGVGGHCIPIYPWFVINLAKK--TNVRLIRTAREINDSMPRHV 315
PY G G GG C P + A++ ++++ A ++N+ PR
Sbjct: 228 IGLDKRIAPY--FLNAGLGYGGSCFPKDTLAFASFARELGEELKIVEAAIKVNEERPRRA 285
Query: 316 VELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYAYDPLC 375
V++ L + +KG I +LG+ F+ + +S A+ + + L + GA V AYDP
Sbjct: 286 VKIMEELLGE----LKGKTICILGIAFKPNTDDTRESVALKIAKLLVDIGANVIAYDPKA 341
Query: 376 TREDAERFGAKWKEDFKDVDAIVIVTDHREFKTLDLKEIAAEVRTKVIVDGRNVIHPEEA 435
E +K +E K D ++I T+ EF+ ++ ++ K ++DGR V+ P +
Sbjct: 342 KTSLVEMVSSK-EECVKRSDGVIIATEWDEFRGIE-----HMLKDKAVLDGRRVLDPNKM 395
Query: 436 KKLGFIYKGVGRV 448
+ + G+ +V
Sbjct: 396 SRSKYRAIGLSKV 408
>pir||C70526 probable UDP-glucose dehydrogenase - Mycobacterium tuberculosis
(strain H37RV) >gi|2193943|emb|CAB09606.1| (Z96800) udgA
[Mycobacterium tuberculosis]
Length = 443
Score = 143 bits (357), Expect = 4e-33
Identities = 123/431 (28%), Positives = 201/431 (46%), Gaps = 17/431 (3%)
Query: 24 AVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEAG 83
+V+G G +G A A G +V+GVDI+ V + G+ E PGL +L+ N+ AG
Sbjct: 4 SVFGTGYLGATHAVGMAQLGHEVVGVDIDPGKVAKLAGGDIPFYE-PGLRKLLTDNLAAG 62
Query: 84 RLKATTDGILAAKKADVMIILV--PTLADDRGNLKLESVYDVAEKISKGLEKGDIVITEA 141
RL+ TTD +AA ADV + V P + G L V+ V + + L + I++ ++
Sbjct: 63 RLRFTTDYDMAADFADVHFLGVGTPQKIGEYG-ADLRHVHAVIDALVPRLVRASILVGKS 121
Query: 142 TMPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASDERTLE- 200
T+P GT L + D +A PE G A+ D ++G D+ T
Sbjct: 122 TVPVGTAAELGHRAGALAPRGVDVEIAWNPEFLREGFAVHDTLNPDRIVLGVQDDSTRAE 181
Query: 201 -AVIGIYETINRKGV-IPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIEI 258
AV +Y + GV ++ ++ AE VKV + I+ N ++ CE G D ++
Sbjct: 182 VAVRELYAPLLAAGVPFLVTDLQTAELVKVSANAFLATKISFINAISEVCEAAGADVSQL 241
Query: 259 FNAANTQPYCHLHM--PGAGVGGHCIPI-YPWFVINLAKKTNVRLIRTAREINDSMPRHV 315
+A P G G GG C+P F+ + + + RE++ R
Sbjct: 242 ADALGYDPRIGRQCLNAGLGFGGGCLPKDIRAFMARAGELGADQALTFLREVDSINMRRR 301
Query: 316 VELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYAYDPLC 375
++ A G + G+ I VLG F+ + SPA++V +L+ GA V+ YDP
Sbjct: 302 TKMVELATTACGGSLLGANIAVLGAAFKPESDDVRDSPALNVAGQLQLNGATVHVYDPKA 361
Query: 376 TREDAER------FGAKWKEDFKDVDAIVIVTDHREFKTLDLKEIAAEVRTKVIVDGRNV 429
++A R + E + DA++++T+ REF L+ ++A VR +VIVDGRN
Sbjct: 362 L-DNAHRLFPTLNYAVSVAEACERADAVLVLTEWREFIDLEPADLANRVRARVIVDGRNC 420
Query: 430 IHPEEAKKLGF 440
+ ++ G+
Sbjct: 421 LDVTRWRRAGW 431
>gi|11497917 UDP-glucose dehydrogenase (ugd-1) [Archaeoglobus fulgidus]
>gi|7431386|pir||F69287 UDP-glucose dehydrogenase
(ugd-1) homolog - Archaeoglobus fulgidus
>gi|2650332|gb|AAB90929.1| (AE001084) UDP-glucose
dehydrogenase (ugd-1) [Archaeoglobus fulgidus]
Length = 324
Score = 136 bits (339), Expect = 5e-31
Identities = 95/312 (30%), Positives = 161/312 (51%), Gaps = 14/312 (4%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
+++ G G +GL FA+ G V+ VD N + S+N+ I E PGL+EL+KKN
Sbjct: 3 VSIIGCGYVGLVTGLGFAELGNPVVFVDSNGSKIKSINDLIPPIYE-PGLEELIKKN--E 59
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGD--IVITE 140
G+ AT D A ++V I V T + + G+L L V + + K+ K L + + +++ +
Sbjct: 60 GKFYATNDYFEALDNSEVSFICVGTPSKEDGSLDLRQVEEASSKLGKALAEKEFHVIVVK 119
Query: 141 ATMPPGTTESLI-PILEK-SGLK-LGDFGLAHAPERTMTGTAIRDITGQYPKIVGASDER 197
+T+ PGTTE+ + PI+EK SG K DFGLA PE G A+ D ++G DER
Sbjct: 120 STVLPGTTENFVKPIIEKESGKKAFDDFGLAMNPEFLREGNAVEDFFNPDRIVIGVKDER 179
Query: 198 TLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIE 257
T + +Y+ + +I + IK AE +K + I+ ANE+ C++ G+D +
Sbjct: 180 TKSVLEELYKPFDCPKLI--TEIKTAEMIKYASNAFLATKISFANEIGNICKKLGIDVYK 237
Query: 258 IFNAANTQPYCH--LHMPGAGVGGHCIPIYPWFVINLAKK--TNVRLIRTAREINDSMPR 313
+F + G G GG C P +I +++ ++++++ E+N+ P
Sbjct: 238 VFEGVGLDHRINPSFFRAGIGFGGSCFPKDVRALIRKSEELGEDLQILKAVIEVNEKQPL 297
Query: 314 HVVELTVRALND 325
++EL + + D
Sbjct: 298 KMIELLKKHIPD 309
>emb|CAB58323.1| (AL121855) UDP-glucose/GDP-mannose family dehydrogenase
[Streptomyces coelicolor A3(2)]
Length = 441
Score = 136 bits (338), Expect = 7e-31
Identities = 104/363 (28%), Positives = 183/363 (49%), Gaps = 22/363 (6%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
++V+GLG +G AA A G +V+GVD+N+ V+ VN+G+ + EE + EL+ + V +
Sbjct: 3 VSVFGLGYVGCVSAACLAGMGHQVVGVDVNQAKVDLVNDGKAPVVEE-RIGELIAEVVGS 61
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGL-EKG-----DI 136
G L+AT D A ++++ ++ V T ++ G+L + V E+I L E+G
Sbjct: 62 GALRATGDVREAIMESEISLVCVGTPSEPNGSLCTTYLERVTEEIGTALAERGGGGGRHT 121
Query: 137 VITEATMPPGTTES-LIPILEK--SGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGA 193
V+ +TM PGT + L+PILEK G DFG+A PE GT++RD ++G
Sbjct: 122 VVFRSTMLPGTCANLLVPILEKYVGGTAGVDFGVAVNPEFLREGTSVRDFFDPPKTVIGE 181
Query: 194 SDERTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGL 253
D +AV+ +Y+++ G + + AEA+K + + + I ANEL C G+
Sbjct: 182 LDAAGGDAVLALYDSL--PGEVFRVPVATAEAIKYADNAFHGLKIGFANELGAVCHALGV 239
Query: 254 DAIEIFNAANTQPYCHLH----MPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREIND 309
D+ ++ + ++ PG GG C+P +++ A++ +V + +
Sbjct: 240 DSHQVMDVFLADRKLNISPAYLRPGFAFGGSCLPKDLRSLVHAAQRADVS-VPILSHVLP 298
Query: 310 SMPRHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVY 369
S H +E V + GK G + GL+F+ G + +SP +++ L G ++
Sbjct: 299 SNSAH-LERAVELVERTGKRRVG----MFGLSFKPGTDDLRESPLVELAERLFGKGYDLR 353
Query: 370 AYD 372
+D
Sbjct: 354 IHD 356
>sp|O07299|ALGD_PSESH GDP-MANNOSE 6-DEHYDROGENASE (GMD) >gi|2160786|gb|AAB58939.1|
(AF001555) GDP mannose dehydrogenase [Pseudomonas
syringae pv. phaseolicola]
Length = 438
Score = 133 bits (332), Expect = 3e-30
Identities = 99/362 (27%), Positives = 172/362 (47%), Gaps = 23/362 (6%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
I+++GLG +G A + G V+GVDI+ ++ +NNG++ I E PGL+EL++K +
Sbjct: 3 ISIFGLGYVGAVCAGCLSARGHDVVGVDISSTKIDLINNGKSPIVE-PGLEELLQKGIST 61
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLE----KGDIVI 138
G+L+ TTD A + D+ +I V T + G+L+L+ + V +I L + IV+
Sbjct: 62 GKLRGTTDFAEAIRATDLSMICVGTPSKKNGDLELDYIESVCREIGYVLRDKATRHTIVV 121
Query: 139 TEATMPPGTTESLIPILEK-SGLKLG-DFGLAHAPERTMTGTAIRDITGQYPKIVGASDE 196
+P +IPILE SG K G DFG+A PE TAI+D ++G D+
Sbjct: 122 RSTVLPGTVANVVIPILEDCSGKKAGVDFGVAVNPEFLRESTAIKDYDLPPMTVIGEFDK 181
Query: 197 RTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAI 256
+ + + +YE ++ I I AE +K ++ + ANE+ + G+D
Sbjct: 182 ASGDVLQSLYEELD--APIIRKDIAVAEMIKYTCNVWHATKVTFANEIGNIAKAVGVDGR 239
Query: 257 EIFNAANTQPYCHLHM----PGAGVGGHCIPIYPWFVINLAKKTNVR--LIRTAREINDS 310
E+ + +L PG GG C+P + A +V L+ + N S
Sbjct: 240 EVMDVVCQDKALNLSQYYMRPGFAFGGSCLPKDVRALTYRASSLDVEAPLLNSLMRSNTS 299
Query: 311 MPRHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYA 370
++ ++ K+ +LGL+F+ G + +SP +++ L G ++
Sbjct: 300 QVQNAFDMVA--------SYDTRKVALLGLSFKAGTDDLRESPLVELAEMLIGKGFDLSI 351
Query: 371 YD 372
+D
Sbjct: 352 FD 353
>gi|10956342 pXO1-95 [Bacillus anthracis] >gi|7474336|pir||G59102 hypothetical
protein pXO1-95 - Bacillus anthracis virulence plasmid
pXO1 >gi|4894311|gb|AAD32399.1|AAD32399 (AF065404)
pXO1-95 [Bacillus anthracis]
Length = 443
Score = 133 bits (331), Expect = 4e-30
Identities = 105/437 (24%), Positives = 198/437 (45%), Gaps = 17/437 (3%)
Query: 21 VTIAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNV 80
+ I++ G G +GL ++ G V +DI+E V + G + I E P L+EL+K N+
Sbjct: 1 MNISIVGTGYVGLVTGVCLSEVGHNVTCIDIDEEKVKKMKLGYSPIFE-PCLEELMKNNI 59
Query: 81 EAGRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITE 140
GRL TT+ + A A++ I V T + G+ L + A I++ ++ I++ +
Sbjct: 60 IKGRLHFTTNYVDGADGAEIFYIAVGTPQKEDGSADLSFIKQAAINIARTIKNDVIIVVK 119
Query: 141 ATMPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASDERTLE 200
+T+P GT + ++ K+ + PE G+A+ D ++G+ ++ +
Sbjct: 120 STVPVGTNIYIKNLILKNLNYDVKVDIISNPEFLREGSAVNDTFYGDRIVIGSENKTSAN 179
Query: 201 AVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIEIFN 260
+ +Y+ I + I++AE +K + I+ N +A CE G D ++
Sbjct: 180 VMEEVYKPFGTP--IFKTDIQSAEMIKYASNTFLATKISFINGIANLCEMVGADVEKVAQ 237
Query: 261 AANTQPYCHLHMPGAGV--GGHCIPIYPWFVINLAK--KTNVRLIRTAREINDSMPRHVV 316
AG+ GG C P ++ +++ + L+ + ++N + ++
Sbjct: 238 GMGQDKRIGSQFLNAGIGYGGSCFPKDTHALVKVSESLQHKFHLLESVIKLNKNQQTVLI 297
Query: 317 ELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYAYDPLCT 376
E + + G KI +LGL+F+ + ++P+I + R+L E GA+V AYDP+
Sbjct: 298 EKIKKRFGS----IVGKKIALLGLSFKPNTDDLREAPSIPIARKLVEEGAQVIAYDPVAI 353
Query: 377 REDAE------RFGAKWKEDFKDVDAIVIVTDHREFKTLDLKEIAAEVRTKVIVDGRNVI 430
+ E + E + D +++T+ E L + + ++ VI DGRN
Sbjct: 354 KNAREVLPKEVHYVYSTMEALTEADIALVLTEWDEVVDSLLLKASQLMKEPVIFDGRNCF 413
Query: 431 HPEEAKKLGFIYKGVGR 447
EAK Y +GR
Sbjct: 414 ELNEAKNYDVEYHSIGR 430
>gb|AAC12870.1| (AF044332) UDP-ManNAc dehydrogenase; RffD [Pectobacterium
carotovorum subsp. atrosepticum]
Length = 287
Score = 125 bits (312), Expect = 7e-28
Identities = 81/275 (29%), Positives = 137/275 (49%), Gaps = 16/275 (5%)
Query: 164 DFGLAHAPERTMTGTAIRDITGQYPKIVGASDERTLEAVIGIYETINRKGVIPMSSIKAA 223
D +A+ PER + G + ++ + +++G +Y I +G +++ + A
Sbjct: 18 DINIAYCPERVLPGQVVVELI-KNDRVIGGMTPVCSARASELYN-IFLEGECVVTNSRTA 75
Query: 224 EAVKVFEGIYRDVNIALANELALWCEEHGLDAIEIFNAANTQPYCHLHMPGAGVGGHCIP 283
E K+ E +RDVNIA ANEL+L C E ++ E+ AN P ++ PG GVGGHCI
Sbjct: 76 EMCKLTENSFRDVNIAFANELSLICAEQNINVWELIRLANRHPRVNILQPGPGVGGHCIA 135
Query: 284 IYPWFVINLAKKTNVRLIRTAREINDSMPRHVVELTVRALND--AGKPMKGSKILV--LG 339
+ PWF++ RLI TAR +ND P VV+ A+ D A + S++ V G
Sbjct: 136 VDPWFIV-AQNPQQARLIHTARLVNDGKPLWVVDRVKAAVADYLAQTDKRASEVTVACFG 194
Query: 340 LTFRGGVKEFTKSPAIDVIRELKEWGAEV-YAYDPLCTREDAERFGAKWKED----FKDV 394
L F+ + + +SPA+ + + +W V +P + G D K+
Sbjct: 195 LAFKPDIDDLRESPAVGITSMIAQWNTGVTLVVEPNVKHLPSVLAGQVKLVDTSSALKEA 254
Query: 395 DAIVIVTDHREFKTLDLKEIAAEVRTKVIVDGRNV 429
D +V++ DHR+FK ++ +V+ + ++D + V
Sbjct: 255 DVLVMLVDHRQFKAIN----PDDVKQQWVIDTKGV 285
>sp|P51585|ALGD_AZOVI GDP-MANNOSE 6-DEHYDROGENASE (GMD) >gi|1001937|gb|AAB01487.1|
(U11240) GDP-mannose dehydrogenase [Azotobacter
vinelandii]
Length = 436
Score = 124 bits (308), Expect = 2e-27
Identities = 102/362 (28%), Positives = 177/362 (48%), Gaps = 23/362 (6%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
I+++GLG +G A + G +V+GVDI+ ++ +N G++ I E PGL EL+ + V+
Sbjct: 3 ISIFGLGYVGAVCAGCLSGRGHEVVGVDISAAKIDMINQGKSPIVE-PGLGELLAEGVKT 61
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLE---KGDIVIT 139
GRL+ TT+ A ++ ++ V T + G+L+L+ + +V ++ L + V+
Sbjct: 62 GRLRGTTNVTEAVLATELSMLCVGTPSKLNGDLELDYIEEVCRQMGSALRDKTERHTVVV 121
Query: 140 EATMPPGTTES-LIPILEK-SGLKLG-DFGLAHAPERTMTGTAIRDITGQYPKIVGASDE 196
+T+ PGT + +IPILE+ SG K G DFG+A PE TAI+D ++G D+
Sbjct: 122 RSTVLPGTVHNVVIPILEEFSGKKAGVDFGVAVNPEFLRESTAIKDYNFPPMTVIGELDK 181
Query: 197 RTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAI 256
+ + IY ++ I I AE +K ++ + ANE+ + G+D
Sbjct: 182 ASGRRLASIYAELD--APIVRKGIAVAEMIKYTCNVWHATKVTFANEIGNIAKAAGVDGR 239
Query: 257 EIF------NAANTQPYCHLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREINDS 310
E+ N N Y PG GG C+ P V L+ + ++ I A I+
Sbjct: 240 EVMEVVCMDNKLNLSQY--YMRPGLAFGGSCL---PKDVSALSYRAHLWDIE-APLISSL 293
Query: 311 MPRHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYA 370
M + + V+ D K+ +LGL+F+ G + +SP +++ L G ++
Sbjct: 294 MRSNAAQ--VQKAYDMIDKHGSRKVALLGLSFKAGTDDLRESPQLELAEMLIGKGFKLSI 351
Query: 371 YD 372
+D
Sbjct: 352 FD 353
>pir||H83203 GDP-mannose 6-dehydrogenase AlgD PA3540 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9949690|gb|AAG06928.1|AE004774_6 (AE004774)
GDP-mannose 6-dehydrogenase AlgD [Pseudomonas
aeruginosa]
Length = 436
Score = 121 bits (301), Expect = 1e-26
Identities = 99/362 (27%), Positives = 176/362 (48%), Gaps = 23/362 (6%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
I+++GLG +G A + G +VIGVD++ ++ +N G++ I E PGL+ L+++ +
Sbjct: 3 ISIFGLGYVGAVCAGCLSARGHEVIGVDVSSTKIDLINQGKSPIVE-PGLEALLQQGRQT 61
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGL-EKGD--IVIT 139
GRL TTD A +DV I V T + G+L L + V +I + EK + V+
Sbjct: 62 GRLSGTTDFKKAVLDSDVSFICVGTPSKKNGDLDLGYIETVCREIGFAIREKSERHTVVV 121
Query: 140 EATMPPGTTES-LIPILEK-SGLKLG-DFGLAHAPERTMTGTAIRDITGQYPKIVGASDE 196
+T+ PGT + +IP++E SG K G DFG+ PE TAI+D ++G D+
Sbjct: 122 RSTVLPGTVNNVVIPLIEDCSGKKAGVDFGVGTNPEFLRESTAIKDYDFPPMTVIGELDK 181
Query: 197 RTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAI 256
+T + + IY ++ I +++ AE +K ++ + ANE+ + G+D
Sbjct: 182 QTGDLLEEIYRELD--APIIRKTVEVAEMIKYTCNVWHAAKVTFANEIGNIAKAVGVDGR 239
Query: 257 EIFNAANTQPYCHLH----MPGAGVGGHCIPIYPWFVINLAKKTNVR--LIRTAREINDS 310
E+ + +L PG GG C+P + A + +V ++ + N +
Sbjct: 240 EVMDVICQDHKLNLSRYYMRPGFAFGGSCLPKDVRALTYRASQLDVEHPMLGSLMRSNSN 299
Query: 311 MPRHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYA 370
+ +L +D K+ +LGL+F+ G + +SP +++ L G E+
Sbjct: 300 QVQKAFDLITS--HDT------RKVGLLGLSFKAGTDDLRESPLVELAEMLIGKGYELRI 351
Query: 371 YD 372
+D
Sbjct: 352 FD 353
>sp|P11759|ALGD_PSEAE GDP-MANNOSE 6-DEHYDROGENASE (GMD) >gi|65967|pir||DEPSGD GDPmannose
6-dehydrogenase (EC 1.1.1.132) - Pseudomonas aeruginosa
>gi|45268|emb|CAA68425.1| (Y00337) GDPmannose
dehydrogenase (AA 1-436) [Pseudomonas aeruginosa]
Length = 436
Score = 120 bits (299), Expect = 2e-26
Identities = 99/362 (27%), Positives = 175/362 (47%), Gaps = 23/362 (6%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
I+++GLG +G A + G +VIGVD++ ++ +N G++ I E PGL+ L+++ +
Sbjct: 3 ISIFGLGYVGAVCAGCLSARGHEVIGVDVSSTKIDLINQGKSPIVE-PGLEALLQQGRQT 61
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGL-EKGD--IVIT 139
GRL TTD A +DV I V T + G+L L + V +I + EK + V+
Sbjct: 62 GRLSGTTDFKKAVLDSDVSFICVGTPSKKNGDLDLGYIETVCREIGFAIREKSERHTVVV 121
Query: 140 EATMPPGTTES-LIPILEK-SGLKLG-DFGLAHAPERTMTGTAIRDITGQYPKIVGASDE 196
+T+ PGT + +IP++E SG K G DFG+ PE TAI+D ++G D+
Sbjct: 122 RSTVLPGTVNNVVIPLIEDCSGKKAGVDFGVGTNPEFLRESTAIKDYDFPPMTVIGELDK 181
Query: 197 RTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAI 256
+T + + IY ++ I +++ AE +K ++ + ANE+ + G+D
Sbjct: 182 QTGDLLEEIYRELD--APIIRKTVEVAEMIKYTCNVWHAAKVTFANEIGNIAKAVGVDGR 239
Query: 257 EIFNAANTQPYCHLH----MPGAGVGGHCIPIYPWFVINLAKKTNVR--LIRTAREINDS 310
E+ + +L PG GG C+P + A + +V ++ + N +
Sbjct: 240 EVMDVICQDHKLNLSRYYMRPGFAFGGSCLPKDVRALTYRASQLDVEHPMLGSLMRSNSN 299
Query: 311 MPRHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYA 370
+ +L +D K+ +LGL+F+ G + +SP +++ L G E
Sbjct: 300 QVQKAFDLITS--HDT------RKVGLLGLSFKAGTDDLRESPLVELAEMLIGKGYEFRI 351
Query: 371 YD 372
+D
Sbjct: 352 FD 353
>gb|AAD44217.2|AF143772_23 (AF143772) GdhgA [Mycobacterium avium]
Length = 346
Score = 115 bits (286), Expect = 8e-25
Identities = 86/315 (27%), Positives = 148/315 (46%), Gaps = 8/315 (2%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
I+V G G +GL A AD+G V+ VDI++ ++ + G I E PGL EL+ +N E
Sbjct: 28 ISVVGSGYVGLVTGACLADSGNDVVCVDIDQAKIDLLLAGGVPIFE-PGLAELIARNREN 86
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITEAT 142
G + TTD + ADV+ I VPT + G L V+ VA+ I +++ +++ ++T
Sbjct: 87 GLIDFTTDRQRGIEHADVIFIAVPTPMGESGAADLTYVFSVADDIGSYIDRYKVIVDKST 146
Query: 143 MPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASDERTLEAV 202
+P GT + + I+ + +F + PE G AI D ++G+ +R L +
Sbjct: 147 VPVGTADQITAIIRSKTDQ--EFDVVSNPEFLKQGKAIADFMQPDRVVIGSDSKRALRIM 204
Query: 203 IGIYETINRK-GVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIEIFNA 261
+YE R + +++AE K + I+ NE++ CE+ G D + A
Sbjct: 205 EELYEPFLRTFHPLIAIDVRSAEMAKYAANCFLATKISFINEMSNLCEKAGADISAVREA 264
Query: 262 --ANTQPYCHLHMPGAGVGGHCIPIYPWFVINLAK--KTNVRLIRTAREINDSMPRHVVE 317
A+ + PG G GG C+P ++ A +++ L+R +ND +V
Sbjct: 265 IGADKRIGYDFLFPGIGYGGSCLPKDVRALLYTADCLGSDMHLLRAVERVNDEQKAALVS 324
Query: 318 LTVRALNDAGKPMKG 332
+ + K + G
Sbjct: 325 KIITRFGGSEKNLDG 339
>gb|AAD20371.1| (AF125999) UDP-D-glucose-dehydrogenase gdhgA [Mycobacterium avium]
Length = 346
Score = 114 bits (282), Expect = 2e-24
Identities = 85/315 (26%), Positives = 147/315 (45%), Gaps = 8/315 (2%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
I+V G G +GL A AD+G V+ VDI++ ++ + G I E PGL EL+ +N E
Sbjct: 28 ISVVGSGYVGLVTGACLADSGNDVVCVDIDQAKIDLLLAGSVPIFE-PGLAELIARNREN 86
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITEAT 142
G + TTD + ADV+ I VPT + G L V+ VA+ I +++ +++ ++T
Sbjct: 87 GLIDFTTDRQRGIEHADVIFIAVPTPMGESGAADLTYVFSVADDIGSYIDRYKVIVDKST 146
Query: 143 MPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASDERTLEAV 202
+P GT + + I+ + +F + PE G AI D ++G+ +R L +
Sbjct: 147 VPVGTADQITAIIRSKTDQ--EFDVVSNPEFLKQGKAIADFMQPDRVVIGSDSKRALRIM 204
Query: 203 IGIYETINRK-GVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIEIFNA 261
+YE R + +++AE K + I+ NE++ CE+ G D + A
Sbjct: 205 EELYEPFLRTFHPLIAIDVRSAEMAKYAANCFLATKISFINEMSNLCEKAGADISAVREA 264
Query: 262 --ANTQPYCHLHMPGAGVGGHCIPIYPWFVINLAK--KTNVRLIRTAREINDSMPRHVVE 317
A+ + PG G G C+P ++ A +++ L+R +ND +V
Sbjct: 265 IGADKRIGYDFLFPGIGYGASCLPKDVRALLYTADCLGSDMHLLRAVERVNDEQKAALVS 324
Query: 318 LTVRALNDAGKPMKG 332
+ + K + G
Sbjct: 325 KIITRFGGSEKNLDG 339
>dbj|BAB07427.1| (AP001519) nucleotide sugar dehydrogenase [Bacillus halodurans]
Length = 388
Score = 110 bits (272), Expect = 4e-23
Identities = 108/407 (26%), Positives = 179/407 (43%), Gaps = 31/407 (7%)
Query: 21 VTIAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNV 80
+ I + G G +GL A + A + VI DI + V+ +NN ++ I + + L K +
Sbjct: 1 MNITIAGTGYVGLSNAVLLAQHN-DVIAYDIVQEKVDMINNRKSPIVDREIEEFLATKEL 59
Query: 81 EAGRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITE 140
L ATTD A K A ++I PT D N S + + +++ +
Sbjct: 60 N---LTATTDKEKAFKDAQFVVISTPTNYDPEKNYFDTSSVEAVISDVLSINPNAVMVIK 116
Query: 141 ATMPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASDERT-L 199
+T+P G T + E+ K + +PE G+A+ D +VG +R +
Sbjct: 117 STIPVGYTRE---VNERFNTK----NIIFSPEFLREGSALYDNLHPSRIVVGERTQRAKI 169
Query: 200 EAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIEIF 259
A + + I + + AEA+K+F Y + +A NEL + E GLDA +I
Sbjct: 170 FAALLVQGAIKENIDVLFTDSTEAEAIKLFANTYLAMRVAFFNELDSYAELKGLDAKQII 229
Query: 260 NAANTQPY--CHLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREINDSMPRHVVE 317
+ P H + P G GG+C+P ++ + +I + ND+ HV
Sbjct: 230 DGVGLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANFEDVPNNIIGAIVDANDTRKDHVAN 289
Query: 318 LTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYAYDPLCTR 377
+ ++ + + + LT + G F +S +DV+ L GAEV Y+P
Sbjct: 290 MILK--------REPKVVGIYRLTMKTGSDNFRQSAILDVMTRLNNAGAEVVVYEPAL-- 339
Query: 378 EDAERF-GAKWKEDFKDVDAI--VIVTDHREFKTLDLKEIAAEVRTK 421
DA F G+K EDF + + VIV + + DLKE+A +V T+
Sbjct: 340 -DATEFDGSKVIEDFAEFKKMSDVIVANR---LSDDLKEVAEKVYTR 382
>dbj|BAB11006.1| (AB009054) UDP-glucose dehydrogenase [Arabidopsis thaliana]
Length = 480
Score = 109 bits (271), Expect = 5e-23
Identities = 119/477 (24%), Positives = 208/477 (42%), Gaps = 61/477 (12%)
Query: 21 VTIAVYGLGKMGLPLAAVFADN--GAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKK 78
V I G G +G P AV A +V VDI+ +N+ N+ + I E PGLD++VK+
Sbjct: 2 VKICCIGAGYVGGPTMAVIALKCPDIEVAVVDISVPRINAWNSDQLPIYE-PGLDDIVKQ 60
Query: 79 NVEAGRLKATTDGILAAKKADVMIILV--PTLADDRGNLKLESV--YDVAEKISKGLEKG 134
L +TD ++AD++ + V PT G K + ++ A ++ +
Sbjct: 61 -CRGKNLFFSTDVEKHVREADIVFVSVNTPTKTTGLGAGKAADLTYWESAARMIADVSVS 119
Query: 135 D-IVITEATMPPGTTESLIPIL--EKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIV 191
D IV+ ++T+P T E++ IL G+K F + PE GTAI D+ ++
Sbjct: 120 DKIVVEKSTVPVKTAEAIEKILMHNSKGIK---FQILSNPEFLAEGTAIADLFNPDRVLI 176
Query: 192 GASDE----RTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALW 247
G + + ++ + +Y +G I +++ +AE K+ + I+ N ++
Sbjct: 177 GGRETPEGFKAVQTLKEVYANWVPEGQIITTNLWSAELSKLAANAFLAQRISSVNAMSAL 236
Query: 248 CEEHGLDAIEIFNAANTQPYCHLHMPGA--GVGGHCIPIYPWFVINLAKKTNVRLIRTAR 305
CE G D ++ A T A G GG C + ++NL +
Sbjct: 237 CESTGADVTQVSYAVGTDSRIGSKFLNASVGFGGSC---FQKDILNLVYICQCNGLPEVA 293
Query: 306 E-------INDSMPRHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVI 358
E IND V V ++ + + K+ +LG F+ + ++PAIDV
Sbjct: 294 EYWKQVIKINDYQKNRFVNRIVSSMFNT---VSNKKVAILGFAFKKDTGDTRETPAIDVC 350
Query: 359 RELKEWGAEVYAYDPLCTREDAERFGAKWKEDF--------------------------- 391
+ L A++ YDP T E +R + K D+
Sbjct: 351 KGLLGDKAQISIYDPQVTEEQIQRDLSMKKFDWDHPLHLQPMSPTTVKQVSVTWDAYEAT 410
Query: 392 KDVDAIVIVTDHREFKTLDLKEIAAEV-RTKVIVDGRNVIHPEEAKKLGFIYKGVGR 447
KD A+ ++T+ EFK+LD ++I + + I DGRN+++ + +++GFI +G+
Sbjct: 411 KDAHAVCVLTEWDEFKSLDYQKIFDNMQKPAFIFDGRNIMNVNKLREIGFIVYSIGK 467
>dbj|BAA99938.1| (AP001309) UDP-glucose dehydrogenase [Arabidopsis thaliana]
Length = 480
Score = 109 bits (271), Expect = 5e-23
Identities = 121/477 (25%), Positives = 202/477 (41%), Gaps = 61/477 (12%)
Query: 21 VTIAVYGLGKMGLPLAAVFADN--GAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKK 78
V I G G +G P AV A +V VDI+ +N+ N+ I E PGLD++VK+
Sbjct: 2 VKICCIGAGYVGGPTMAVIALKCPDVEVAVVDISVPRINAWNSDTLPIYE-PGLDDVVKQ 60
Query: 79 NVEAGRLKATTDGILAAKKADVMIILVPTLADDRG-----NLKLESVYDVAEKISKGLEK 133
L +TD ++AD++ + V T RG L A I+
Sbjct: 61 -CRGKNLFFSTDVEKHVREADIVFVSVNTPTKTRGLGAGKAADLTYWESAARMIADVSVS 119
Query: 134 GDIVITEATMPPGTTESLIPIL--EKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIV 191
IV+ ++T+P T E++ IL G+K F + PE GTAI+D+ ++
Sbjct: 120 DKIVVEKSTVPVKTAEAIEKILTHNSKGIK---FQILSNPEFLAEGTAIKDLFNPDRVLI 176
Query: 192 GASDE----RTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALW 247
G + + ++ + +Y +G I +++ +AE K+ + I+ N ++
Sbjct: 177 GGRETPEGFKAVQTLKNVYAHWVPEGQIITTNLWSAELSKLAANAFLAQRISSVNAMSAL 236
Query: 248 CEEHGLDAIEIFNAANTQPYCHLHM--PGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAR 305
CE G D ++ A T G GG C + ++NL +
Sbjct: 237 CEATGADVTQVSYAVGTDSRIGPKFLNSSVGFGGSC---FQKDILNLVYICECNGLPEVA 293
Query: 306 E-------INDSMPRHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVI 358
E IND V V ++ ++ + KI VLG F+ + ++PAIDV
Sbjct: 294 EYWKQVIKINDYQKSRFVNRVVSSMFNS---VSNKKIAVLGFAFKKDTGDTRETPAIDVC 350
Query: 359 RELKEWGAEVYAYDPLCTREDAERFGAKWKEDF--------------------------- 391
+ L E A + YDP T + +R + K D+
Sbjct: 351 KGLLEDKARLSIYDPQVTEDQIQRDLSMNKFDWDHPLHLQPMSPTTVKQVTVTWDAYEAT 410
Query: 392 KDVDAIVIVTDHREFKTLDLKEIAAEVRTKVIV-DGRNVIHPEEAKKLGFIYKGVGR 447
KD I I+T+ EFK LD ++I ++ V DGRN+++ ++ +++GFI +G+
Sbjct: 411 KDAHGICIMTEWDEFKNLDFQKIFDNMQKPAFVFDGRNIMNLQKLREIGFIVYSIGK 467
>gb|AAF98561.1|AC013427_4 (AC013427) Strong similarity to UDP-Glucose 6-Dehydrogenase from
Glycine max gb|6136119 and is a member of the
UDP-glucose/GDP-mannose dehydrogenase PF|00984 family.
ESTs gb|AV566422, gb|AV555903 come from this gene.
[Arabidopsis thaliana]
Length = 481
Score = 107 bits (265), Expect = 2e-22
Identities = 117/475 (24%), Positives = 202/475 (41%), Gaps = 56/475 (11%)
Query: 21 VTIAVYGLGKMGLPLAAVFADN--GAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKK 78
V I G G +G P AV A +V+ VDI+E +N+ N+ I E PGL+++VK+
Sbjct: 2 VKICCIGAGYVGGPTMAVMALKCPEIEVVVVDISEPRINAWNSDRLPIYE-PGLEDVVKQ 60
Query: 79 NVEAGRLKATTDGILAAKKADVMIILV--PTLADDRGNLKLESVY---DVAEKISKGLEK 133
L +TD ++D++ + V PT G K + A I+ +
Sbjct: 61 -CRGKNLFFSTDVEKHVFESDIVFVSVNTPTKTQGLGAGKAADLTYWESAARMIADVSKS 119
Query: 134 GDIVITEATMPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGA 193
IV+ ++T+P T E++ IL + + +F + PE GTAI+D+ ++G
Sbjct: 120 SKIVVEKSTVPVRTAEAIEKILTHNSKGI-EFQILSNPEFLAEGTAIKDLYNPDRVLIGG 178
Query: 194 SD----ERTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCE 249
D ++ ++A+ +Y I +++ +AE K+ + I+ N ++ CE
Sbjct: 179 RDTAAGQKAIKALRDVYAHWVPVEQIICTNLWSAELSKLAANAFLAQRISSVNAMSALCE 238
Query: 250 EHGLDAIEIFNAANTQPYCHLHMPGA--GVGGHCIP------IYPWFVINLAKKTNVRLI 301
G D ++ +A T A G GG C IY L + N
Sbjct: 239 ATGADVTQVAHAVGTDTRIGPKFLNASVGFGGSCFQKDILNLIYICECNGLPEAANYW-- 296
Query: 302 RTAREINDSMPRHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIREL 361
+ ++ND + R ++ + G KI +LG F+ + ++PAIDV L
Sbjct: 297 KQVVKVNDYQK---IRFANRVVSSMFNTVSGKKIAILGFAFKKDTGDTRETPAIDVCNRL 353
Query: 362 KEWGAEVYAYDPLCTREDAERFGAKWKEDF----------------------------KD 393
A++ YDP E R + + D+ KD
Sbjct: 354 VADKAKLSIYDPQVLEEQIRRDLSMARFDWDHPVPLQQIKAEGISEQVNVVSDAYEATKD 413
Query: 394 VDAIVIVTDHREFKTLDLKEIAAEVRTKVIV-DGRNVIHPEEAKKLGFIYKGVGR 447
+ ++T+ EFK+LD K+I ++ V DGRNV+ + +++GFI +G+
Sbjct: 414 AHGLCVLTEWDEFKSLDFKKIFDNMQKPAFVFDGRNVVDAVKLREIGFIVYSIGK 468
>pir||JC2525 UDP-glucose dehydrogenase (EC 1.1.99.-) - Xanthomonas campestris
pv. campestris >gi|747911|emb|CAA56166.1| (X79772)
UDP-glucose dehydrogenase [Xanthomonas campestris]
Length = 445
Score = 105 bits (260), Expect = 9e-22
Identities = 86/338 (25%), Positives = 143/338 (41%), Gaps = 29/338 (8%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
+A++G G +GL A+ G VI VDI++ V+ +N G I E PGL+ +VK N +
Sbjct: 3 VAIFGTGYVGLVTGTCLAEVGHHVICVDIDQAKVDGLNRGVIPIYE-PGLEPMVKGNHAS 61
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITEAT 142
GRL+ TTD A ++ I V T D+ G+ L+ V VA + + ++ +++ ++T
Sbjct: 62 GRLRFTTDAAEAIAHGEITFIAVGTPPDEDGSADLQYVLAVARTVGRHIDGPSVIVNKST 121
Query: 143 MPPGTTESLIPILEKSGLKLG---DFGLAHAPERTMTGTAIRDITGQYPKIVGASDERTL 199
+P T + + +++ G +F + PE G A+ D ++GA +
Sbjct: 122 VPVRTADKVRAAIQEELDARGVDHEFDVVSNPEFLKEGDAVADCMRPDRIVIGAKKPAAI 181
Query: 200 EAVIGIYETINR-KGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIEI 258
+ +Y NR + I +++AE K I+ NE+A E G D +
Sbjct: 182 ARMRRLYAPFNRNRDRIVEMDVRSAELTKYAANAMLATKISFMNEIANIAERVGADVEHV 241
Query: 259 FNAANTQPYCHLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTARE------------ 306
N + P H IYP A + +TA E
Sbjct: 242 RNGIGSDPRIGWHF-----------IYPVPATARASRRCAGARKTAHEYGMQPTLLNAVE 290
Query: 307 -INDSMPRHVVELTVRALNDAGKPMKGSKILVLGLTFR 343
+N++ H+ EL R D + G V GL F+
Sbjct: 291 SVNNAQKGHLFELVQRHYADGNGSIAGKTFAVWGLAFK 328
>gb|AAD45294.1|AF156256_2 (AF156256) putative dehydrogenase [Vibrio anguillarum]
Length = 237
Score = 105 bits (259), Expect = 1e-21
Identities = 79/233 (33%), Positives = 118/233 (49%), Gaps = 11/233 (4%)
Query: 16 IKNGDVTIAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDEL 75
+K +V I + GLG +GLPLA F + V G DIN++ V +++G + E
Sbjct: 1 MKLENVKIGIIGLGYVGLPLAVEFGKKFSTV-GFDINQKRVAELHSGIDLTLE------C 53
Query: 76 VKKNVEAGRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGD 135
++ + + L + T + K + I+ VPT D L + +E ++K + GD
Sbjct: 54 SEEELRSAPLLSYTHQLEEIKDCNFYIVTVPTPITDEKTPDLNPLKKASEALAKVVSHGD 113
Query: 136 IVITEATMPPGTTESL-IPILEK-SGLKLG-DFGLAHAPERTMTGTAIRDITGQYPKIVG 192
IV+ E+T+ PG TE + +PI+EK SGL DF ++PER G + +T KI
Sbjct: 114 IVVFESTVYPGATEEVCLPIIEKNSGLVFNRDFFAGYSPERINPGDKVNRLT-TIMKITS 172
Query: 193 ASDERTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELA 245
S + V +Y +I G SIK AEA KV E RD+NIA+ NE A
Sbjct: 173 GSTPEVADFVDQVYSSIVTAGTHKAPSIKVAEAAKVIENTQRDLNIAVINEFA 225
>gb|AAC67251.2| (AF067175) UDP-glucose dehydrogenase [Pasteurella multocida]
Length = 390
Score = 102 bits (252), Expect = 8e-21
Identities = 101/375 (26%), Positives = 169/375 (44%), Gaps = 44/375 (11%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
I + G G +GL A + A + VI +DI++ V+ +NN ++ I ++ D L K++
Sbjct: 4 ITIAGAGYVGLSNAVLLAQHH-NVILLDIDQNKVDLINNKKSPITDKEIEDFLQNKSLT- 61
Query: 83 GRLKATTDGILAAKKADVMIILVPT-LADDRGNLKLESVYDVAEKISKGLEKGDIVITEA 141
+ ATTD +A K AD +II PT + G +V V E+ + + +I ++
Sbjct: 62 --MMATTDKEVALKNADFVIIATPTDYNTETGYFNTSTVEAVIEQ-TLSINPQATIIIKS 118
Query: 142 TMPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPK--IVGASDERTL 199
T+P G TE++ K L +PE G A+ D YP IVG++ +
Sbjct: 119 TIPVGFTENMRE-------KFNTPNLIFSPEFVREGKALYD--NLYPSRIIVGSTSYQAK 169
Query: 200 EAVIGIYETINRKGVIPMSSIKA-AEAVKVFEGIYRDVNIALANELALWCEEHGLDAIEI 258
+ + +K V + + AEAVK+F Y + +A NEL + H L+ +I
Sbjct: 170 VFADMLTQCARKKDVTVLFTHNTEAEAVKLFANTYLAMRVAFFNELDTYASLHHLNTKDI 229
Query: 259 FNAANTQPY--CHLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREINDSMPRHVV 316
N +T P H + P G GG+C+P K T L A +P++++
Sbjct: 230 INGISTDPRIGTHYNNPSFGYGGYCLP----------KDTKQLLANYA-----DVPQNLI 274
Query: 317 ELTVRALNDAGKPM--------KGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEV 368
E V++ N+ K K + + L + G F S +D++ LKE G E+
Sbjct: 275 EAIVKS-NETRKRFITHDVLNKKPKTVGIYRLIMKSGSDNFRASAILDIMPHLKENGVEI 333
Query: 369 YAYDPLCTREDAERF 383
Y+P ++ E +
Sbjct: 334 VIYEPTLNQQAFEDY 348
>pir||T51527 UDP-glucose dehydrogenase-like protein - Arabidopsis thaliana
>gi|9755804|emb|CAC01748.1| (AL391143) UDP-glucose
dehydrogenase-like protein [Arabidopsis thaliana]
Length = 480
Score = 101 bits (248), Expect = 2e-20
Identities = 122/477 (25%), Positives = 195/477 (40%), Gaps = 61/477 (12%)
Query: 21 VTIAVYGLGKMGLPLAAVFADN--GAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKK 78
V I G G +G P AV A +V VDI+ +N+ N+ + I E PGLD++VK+
Sbjct: 2 VKICCIGAGYVGGPTMAVIALKCPSVEVAVVDISVPRINAWNSDQLPIYE-PGLDDVVKQ 60
Query: 79 NVEAGRLKATTDGILAAKKADVMIILVPTLADDRG-----NLKLESVYDVAEKISKGLEK 133
L +TD ++AD++ + V T RG L A I+
Sbjct: 61 -CRGKNLFFSTDVEKHVREADIVFVSVNTPTKTRGLGAGKAADLTYWESAARMIADVSVS 119
Query: 134 GDIVITEATMPPGTTESLIPIL--EKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIV 191
IV+ ++T+P T E++ IL G+K F + PE GTAI D+ ++
Sbjct: 120 DKIVVEKSTVPVKTAEAIEKILTHNSKGIK---FQILSNPEFLAEGTAIEDLFMPDRVLI 176
Query: 192 GASDER----TLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALW 247
G + ++A+ IY + I +++ +AE K+ + I+ N ++
Sbjct: 177 GGRETTEGFAAVKALKDIYAQWVPEERILTTNLWSAELSKLAANAFLAQRISSVNAMSAL 236
Query: 248 CEEHGLDAIEIFNAANTQPYCHLHM--PGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAR 305
CE G + E+ A G GG C + ++NL +
Sbjct: 237 CEATGANVSEVSYAVGKDSRIGPKFLNSSVGFGGSC---FQKDILNLVYICECNGLPEVA 293
Query: 306 E-------INDSMPRHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVI 358
E IND V V ++ + + KI VLG F+ + ++PAIDV
Sbjct: 294 EYWKQVIKINDYQKTRFVNRIVSSMFNT---VSNKKIAVLGFAFKKDTGDTRETPAIDVC 350
Query: 359 RELKEWGAEVYAYDPLCTREDAERFGAKWKEDF--------------------------- 391
+ L A + YDP T E +R K D+
Sbjct: 351 KGLLGDKARLSIYDPQVTEEQIQRDLTMNKFDWDHPLHLQPMSPTTVKQVSVAWDAYTAT 410
Query: 392 KDVDAIVIVTDHREFKTLDLKEIAAEVRTKVIV-DGRNVIHPEEAKKLGFIYKGVGR 447
KD I I+T+ EFK LD + I ++ V DGRNV+ ++ +++GFI +G+
Sbjct: 411 KDAHGICILTEWDEFKKLDFQRIFENMQKPAFVFDGRNVVDADKLREIGFIVYSIGK 467
>sp|Q96558|UGDH_SOYBN UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|7431381|pir||T08818 probable UDPglucose
6-dehydrogenase (EC 1.1.1.22) - soybean
>gi|1518540|gb|AAB58398.1| (U53418) UDP-glucose
dehydrogenase [Glycine max]
Length = 480
Score = 101 bits (248), Expect = 2e-20
Identities = 117/477 (24%), Positives = 206/477 (42%), Gaps = 61/477 (12%)
Query: 21 VTIAVYGLGKMGLPLAAVFADN--GAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKK 78
V I G G +G P AV A +V VDI++ + + N+ + I E PGLD +VK+
Sbjct: 2 VKICCIGAGYVGGPTMAVIALKCPSIEVAVVDISKSRIAAWNSDQLPIYE-PGLDGVVKQ 60
Query: 79 NVEAGRLKATTDGILAAKKADVMIILV--PTLADDRGNLKLESV--YDVAEKISKGLEKG 134
L +TD +AD++ + V PT G K + ++ A ++ + K
Sbjct: 61 -CRGKNLFFSTDVEKHVFEADIVFVSVNTPTKTQGLGAGKAADLTYWESAARMIADVSKS 119
Query: 135 D-IVITEATMPPGTTESLIPIL--EKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIV 191
D IV+ ++T+P T E++ IL G+K F + PE GTAI+D+ ++
Sbjct: 120 DKIVVEKSTVPVKTAEAIEKILTHNSKGIK---FQILSNPEFLAEGTAIKDLFNPDRVLI 176
Query: 192 GASD----ERTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALW 247
G + ++ ++ + +Y + I +++ +AE K+ + I+ N ++
Sbjct: 177 GGRETPEGQKAIQTLKDVYAQWVPEERILTTNLWSAELSKLAANAFLAQRISSVNAMSAL 236
Query: 248 CEEHGLDAIEIFNAANTQPYCHLHMPGA--GVGGHCIPIYPWFVINLAKKTNVRLIRTAR 305
CE G + ++ + T A G GG C + ++NL +
Sbjct: 237 CEATGANVQQVSYSVGTDSRIGPKFLNASVGFGGSC---FQKDILNLVYICECNGLPEVA 293
Query: 306 E-------INDSMPRHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVI 358
E IND V V ++ + + KI +LG F+ + ++PAIDV
Sbjct: 294 EYWKQVIKINDYQKSRFVNRVVASMFNT---VSNKKIAILGFAFKKDTGDTRETPAIDVC 350
Query: 359 RELKEWGAEVYAYDPLCTREDAERFGAKWKEDF--------------------------- 391
+ L A + YDP T + +R + K D+
Sbjct: 351 QGLLGDKANLSIYDPQVTEDQIQRDLSMNKFDWDHPIHLQPTSPTTVKKVSVVWDAYEAT 410
Query: 392 KDVDAIVIVTDHREFKTLDLKEIAAEVRTKVIV-DGRNVIHPEEAKKLGFIYKGVGR 447
KD + I+T+ EFKTLD ++I ++ V DGRN++ ++ +++GFI +G+
Sbjct: 411 KDAHGLCILTEWDEFKTLDYQKIFDNMQKPAFVFDGRNIVDADKLREIGFIVYSIGK 467
>sp|O02373|UGDH_DROME UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) (SUGARLESS PROTEIN) >gi|2149991|gb|AAB58714.1|
(AF000570) UDP-glucose dehydrogenase [Drosophila
melanogaster] >gi|2257994|gb|AAB63208.1| (AF007870)
UDP-glucose dehydrogenase [Drosophila melanogaster]
>gi|2266945|gb|AAB63462.1| (AF009013)
UDP-glucose-6-dehydrogenase [Drosophila melanogaster]
>gi|7295310|gb|AAF50631.1| (AE003560) sgl gene product
[Drosophila melanogaster]
Length = 476
Score = 99.8 bits (245), Expect = 5e-20
Identities = 115/464 (24%), Positives = 198/464 (41%), Gaps = 46/464 (9%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIG--VDINERVVNSVNNGENHIKEEPGLDELVKK-- 78
+ G G +G P AV A ++ VD + + N+ + I E PGLDE+VKK
Sbjct: 3 VCCIGAGYVGGPTCAVMALKCPDIVITLVDKSSERIAQWNSDKLPIYE-PGLDEVVKKCR 61
Query: 79 NVEAGRLKATTDGILAAKKADVMIILVPTLADDRGNLK-----LESVYDVAEKISKGLEK 133
NV L +TD A K+AD++ I V T GN K L+ V A I++ +
Sbjct: 62 NVN---LFFSTDIETAIKEADLIFISVNTPTKTCGNGKGRAADLKYVESAARMIAEIAQS 118
Query: 134 GDIVITEATMPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGA 193
IV+ ++T+P ES++ IL + + + PE GTAI D+ ++G
Sbjct: 119 NKIVVEKSTVPVRAAESIMHILRANQKPGIHYDILSNPEFLAEGTAINDLLNADRVLIGG 178
Query: 194 SD----ERTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCE 249
+ + +E + IYE K I ++ ++E K+ + I+ N L+ CE
Sbjct: 179 EETPEGHQAVEKLSWIYEHWIPKQNILTTNTWSSELSKLAANAFLAQRISSINSLSAVCE 238
Query: 250 EHGLDAIEIFNAA--NTQPYCHLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLI----RT 303
G D E+ A +++ G GG C +I + + N+ + +
Sbjct: 239 ATGADVSEVARAVGLDSRIGSKFLQASVGFGGSCFQKDILNLIYICENLNLPEVAAYWQQ 298
Query: 304 AREINDSMPRHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKE 363
++N+ R + + +L + + +I +LG F+ + ++ AI V + L E
Sbjct: 299 VIDMNEYQKRRFSQKIIESLFNT---VSDKRIAILGFAFKKNTGDTRETAAITVCQTLLE 355
Query: 364 WGAEVYAYDPLCTRED-------------------AERFGAKWKEDFKDVDAIVIVTDHR 404
GA + YDP E A + + + A+VI T+
Sbjct: 356 EGAALDIYDPKVEPEQIIDDLTHPSVTESPEKVKKAVQIHSDPYSAVRATHALVICTEWD 415
Query: 405 EFKTLDLKEI-AAEVRTKVIVDGRNVIHPEEAKKLGFIYKGVGR 447
EF LD K I + ++ I DGR ++ E +++GF + +G+
Sbjct: 416 EFVDLDFKRIYQSMMKPAYIFDGRKILDHERLQQIGFHVQTIGK 459
>gb|AAC97125.1| (AF001310) UDP-glucose dehydrogenase [Drosophila melanogaster]
Length = 476
Score = 98.7 bits (242), Expect = 1e-19
Identities = 114/464 (24%), Positives = 198/464 (42%), Gaps = 46/464 (9%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIG--VDINERVVNSVNNGENHIKEEPGLDELVKK-- 78
+ G G +G P AV A ++ VD + + N+ + I E PGLDE+VK+
Sbjct: 3 VCCIGAGYVGGPTCAVMALKCPDIVITLVDKSSERIAQWNSDKLPIYE-PGLDEVVKRCR 61
Query: 79 NVEAGRLKATTDGILAAKKADVMIILVPTLADDRGNLK-----LESVYDVAEKISKGLEK 133
NV L +TD A K+AD++ I V T GN K L+ V A I++ +
Sbjct: 62 NVN---LFFSTDIETAIKEADLIFISVNTPTKTCGNGKGRAADLKYVESAARMIAEIAQS 118
Query: 134 GDIVITEATMPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGA 193
IV+ ++T+P ES++ IL + + + PE GTAI D+ ++G
Sbjct: 119 NKIVVEKSTVPVRAAESIMHILRANQKPGIHYDILSNPEFLAEGTAINDLLNADRVLIGG 178
Query: 194 SD----ERTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCE 249
+ + +E + IYE K I ++ ++E K+ + I+ N L+ CE
Sbjct: 179 EETPEGHQAVEKLSWIYEHWIPKQNILTTNTWSSELSKLAANAFLAQRISSINSLSAVCE 238
Query: 250 EHGLDAIEIFNAA--NTQPYCHLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLI----RT 303
G D E+ A +++ G GG C +I + + N+ + +
Sbjct: 239 ATGADVSEVARAVGLDSRIGSKFLQASVGFGGSCFQKDILNLIYICENLNLPEVAAYWQQ 298
Query: 304 AREINDSMPRHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKE 363
++N+ R + + +L + + +I +LG F+ + ++ AI V + L E
Sbjct: 299 VIDMNEYQKRRFSQKIIESLFNT---VSDKRIAILGFAFKKNTGDTRETAAITVCQTLLE 355
Query: 364 WGAEVYAYDPLCTRED-------------------AERFGAKWKEDFKDVDAIVIVTDHR 404
GA + YDP E A + + + A+VI T+
Sbjct: 356 EGAALDIYDPKVEPEQIIDDLTHPSVTESPEKVKKAVQIHSDPYSAVRATHALVICTEWD 415
Query: 405 EFKTLDLKEI-AAEVRTKVIVDGRNVIHPEEAKKLGFIYKGVGR 447
EF LD K I + ++ I DGR ++ E +++GF + +G+
Sbjct: 416 EFVDLDFKRIYQSMMKPAYIFDGRKILDHERLQQIGFHVQTIGK 459
>pir||S70888 nucleotide sugar dehydrogenase homolog - Vibrio cholerae
>gi|1230584|gb|AAC46249.1| (U47057) nucleotide sugar
dehydrogenase [Vibrio cholerae O139]
>gi|3724323|dbj|BAA33612.1| (AB012956) probable
nucleotide sugar dehydrogenase [Vibrio cholerae]
>gi|1588978|prf||2209416H nucleotide sugar dehydrogenase
[Vibrio cholerae]
Length = 388
Score = 97.9 bits (240), Expect = 2e-19
Identities = 110/413 (26%), Positives = 180/413 (42%), Gaps = 47/413 (11%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
IAV G G +GL A + A + +VI VDI V +NN ++ I ++ L K ++
Sbjct: 3 IAVAGTGYVGLSNAMLLAQHH-QVIAVDIIAEKVAMLNNKQSPIVDQEIEYFLAHKTLD- 60
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGN-LKLESVYDVAEKISKGLEKGDIVITEA 141
+AT D A + AD +II PT D + N SV V +++ + +++ ++
Sbjct: 61 --FQATLDKQSAYRNADFVIIATPTDYDPQTNYFNTTSVESVIKEVM-AINPQAVMVIKS 117
Query: 142 TMPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASDERTLEA 201
T+P G T + +LG + +PE G A+ D IVG ER
Sbjct: 118 TVPVGYTARIKE-------QLGCDNILFSPEFLREGKALHDNLHPSRIIVGERSERAEVF 170
Query: 202 VIGIYETINRKGV-IPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIEIFN 260
+ E +K + + + AEAVK+F Y + +A NEL + E HGLDA +I
Sbjct: 171 ANLLVEGAVKKNIPVLFTDSTEAEAVKLFSNTYLAMRVAYFNELDSYAEAHGLDARQIIE 230
Query: 261 AANTQPYC--HLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREINDSMPRHVVEL 318
P H + P G GG+C+P K T L + S+P +++
Sbjct: 231 GVGLDPRIGNHYNNPSFGYGGYCLP----------KDTKQLLANYS-----SVPNNIIGA 275
Query: 319 TVRALNDAGKPMKGSKIL--------VLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYA 370
V A N K I+ + L + G F S +++ +K G EV
Sbjct: 276 IVEA-NRTRKDFVADSIIKRQPKVVGIYRLIMKAGSDNFRASSIQGIMKRIKAKGIEVVV 334
Query: 371 YDPLCTREDAERFGAKWKEDFKDV--DAIVIVTDHREFKTLDLKEIAAEVRTK 421
Y+P+ ++ E F ++ +D + A VIV++ +L ++A +V T+
Sbjct: 335 YEPVL--DEPEFFHSRVIKDLDEFKQTADVIVSNR---MVEELADVADKVYTR 382
>sp|O33952|UDG8_ECOLI UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|2586097|gb|AAC45829.1| (U78086)
hypothetical uridine-5'-diphosphoglucose dehydrogenase
[Escherichia coli]
Length = 388
Score = 97.1 bits (238), Expect = 4e-19
Identities = 101/412 (24%), Positives = 181/412 (43%), Gaps = 45/412 (10%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
I + G G +GL + A N +V+ +DI + V+ +N ++ I ++ + L K++
Sbjct: 3 ITISGTGYVGLSNGILIAQNH-EVVALDIVQAKVDMLNKKQSPIVDKEIEEYLATKDLN- 60
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITEAT 142
+ATTD A K AD +II PT D + N S + + + +++ ++T
Sbjct: 61 --FRATTDKYDAYKNADYVIIATPTDYDPKTNYFNTSSVEAVIRDVTEINPNAVMVIKST 118
Query: 143 MPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASDERTLEAV 202
+P G T+S+ +LG L +PE G A+ D ++G ER
Sbjct: 119 IPVGFTKSIKE-------RLGIDNLIFSPEFLREGKALYDNLHPSRIVIGERSERAERFA 171
Query: 203 IGIYETINRKGVIPM-SSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIEIFNA 261
+ E ++ + + + AEA+K+F Y + +A NEL + E GL+ +I
Sbjct: 172 ALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLNTRQIIEG 231
Query: 262 ANTQPYC--HLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREINDSMPRHVVELT 319
P H + P G GG+C+P K +L+ + S+P +++
Sbjct: 232 VCLDPRIGNHYNNPSFGYGGYCLP-----------KDTKQLLANYQ----SVPNNLISAI 276
Query: 320 VRA-------LNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYAYD 372
V A + DA K + + L + G F S +++ +K G EV Y+
Sbjct: 277 VDANRTRKDFIADAILSRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVIIYE 336
Query: 373 PLCTREDAERFGAKWKED---FKDVDAIVIVTDHREFKTLDLKEIAAEVRTK 421
P+ +ED+ F ++ + D FK ++I E +LK++A +V T+
Sbjct: 337 PV-MKEDS-FFNSRLERDLATFKQQADVIISNRMAE----ELKDVADKVYTR 382
>pir||T44338 hypothetical protein wbfV [imported] - Vibrio cholerae
>gi|3721692|dbj|BAA33642.1| (AB012957) probable
nucleotide sugar dehydrogenase [Vibrio cholerae]
Length = 388
Score = 96.3 bits (236), Expect = 6e-19
Identities = 107/408 (26%), Positives = 179/408 (43%), Gaps = 37/408 (9%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
IAV G G +GL A + A + +VI VDI V +NN ++ I ++ L K ++
Sbjct: 3 IAVAGTGYVGLSNAILLAQHH-QVIAVDIIAEKVAMLNNKQSPIVDQEIEYFLAHKTLD- 60
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGN-LKLESVYDVAEKISKGLEKGDIVITEA 141
+AT D A + AD +II PT D + N SV V +++ + +++ ++
Sbjct: 61 --FQATLDKQSAYRDADFVIIATPTDYDPQTNYFNTTSVESVIKEVM-AINPQAVMVIKS 117
Query: 142 TMPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASDERTLEA 201
T+P G T + +LG + +PE G A+ D IVG ER
Sbjct: 118 TVPVGYTVRIKN-------QLGCDNILFSPEFLREGKALHDNLHPSRIIVGERSERAKVF 170
Query: 202 VIGIYETINRKGV-IPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIEIFN 260
+ E +K + + + AEAVK+F Y + +A NEL + E HGLDA +I
Sbjct: 171 ANLLVEGAVKKNIPVLFTDSTEAEAVKLFSNTYLAMRVAYFNELDSYAEAHGLDARQIIE 230
Query: 261 AANTQPYC--HLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREINDSMPRHVVEL 318
P H + P G GG+C+P K +L+ + +S+ +VE
Sbjct: 231 GVGLDPRIGNHYNNPSFGYGGYCLP-----------KDTKQLLANYSSVPNSIIGAIVEA 279
Query: 319 TVRALNDAGKPMKGSKILVLG---LTFRGGVKEFTKSPAIDVIRELKEWGAEVYAYDPLC 375
+ + + V+G L + G F S +++ +K G EV Y+P+
Sbjct: 280 NRTRKDFVADSIIKRQPKVVGIYRLIMKAGSDNFRASSIQGIMKRIKAKGIEVVVYEPVL 339
Query: 376 TREDAERFGAKWKEDFKDV--DAIVIVTDHREFKTLDLKEIAAEVRTK 421
+ E F ++ +D + A VIV++ +L ++A +V T+
Sbjct: 340 --NEPEFFHSRVIKDLNEFKQTADVIVSNR---MVEELADVADKVYTR 382
>emb|CAB46919.2| (AJ242946) putative UDP-glucose dehydrogenase [Streptococcus
uberis]
Length = 401
Score = 96.3 bits (236), Expect = 6e-19
Identities = 99/406 (24%), Positives = 179/406 (43%), Gaps = 33/406 (8%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
IAV G G +GL L+ + A + VDI E+ VN +N ++ I++ + L +K ++
Sbjct: 3 IAVAGSGYVGLSLSVLLAQKNPVTV-VDIIEKKVNLINQKQSPIQDVDIENYLKEKKLQ- 60
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITEAT 142
L+AT D A + AD++II PT D N S + + + L +++ ++T
Sbjct: 61 --LRATLDADQAFRDADILIIATPTNYDVEKNFFDTSHVETVIEKALALNSQALLVIKST 118
Query: 143 MPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPK--IVGASDERTLE 200
+P G ++K K + +PE A++D YP IV D+ ++E
Sbjct: 119 IPLG-------FIKKMRQKYQTDRIIFSPEFLRESKALKD--NLYPSRIIVSFEDDDSME 169
Query: 201 AV--IGIYETINRKG-------VIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEH 251
+ + + + G V+ M S + AEAVK+F Y + ++ NEL + E++
Sbjct: 170 VIEAAKTFAQLLKDGSLDKDVPVLFMGSAE-AEAVKLFANTYLAMRVSYFNELDTYAEKN 228
Query: 252 GLDAIEIFNAA--NTQPYCHLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREIND 309
GL I + + H + P G GG+C+P ++ LI+ + N
Sbjct: 229 GLRVDNIIEGVCHDRRIGIHYNNPSFGYGGYCLPKDTKQLLAGYDGIPQSLIKAIVDSNK 288
Query: 310 SMPRHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVY 369
++ ++ L+D K + I + L + F +S D+I +K + +
Sbjct: 289 IRKEYIASQILQQLSDINVDPKDATIGIYRLIMKSNSDNFRESAIKDIIDHIKSYQINIV 348
Query: 370 AYDPLCTREDAERFGAKWKEDFKDVDAI--VIVTDHREFKTLDLKE 413
Y+P+ E F +D D A+ +IV++ + D+KE
Sbjct: 349 LYEPMMN----EDFDLPIIDDLSDFKAMSHIIVSNRYDLALEDVKE 390
>gb|AAF04455.1|AF053973_1 (AF053973) UDP-glucose dehydrogenase [Populus tremula x Populus
tremuloides]
Length = 481
Score = 95.6 bits (234), Expect = 1e-18
Identities = 119/478 (24%), Positives = 202/478 (41%), Gaps = 62/478 (12%)
Query: 21 VTIAVYGLGKMGLPLAAVFADN--GAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKK 78
V I G G +G P AV A +V+ VDI E + + N+ + I E PGL ++VK+
Sbjct: 2 VKICCIGAGYVGGPTMAVIALKCPSIEVVVVDIWEPRIAAWNSDQLPIYE-PGLYDVVKE 60
Query: 79 NVEAGRLKATTDGILAAKKADVMIILV--PTLADDRGNLKLESV--YDVAEKISKGLEKG 134
L + D +AD++ + V PT G K + ++ A + + K
Sbjct: 61 -CRGRNLFFSKDVEKHVAEADIVFVSVNTPTKTQGLGAGKAADLTYWESAARTIADVSKS 119
Query: 135 D-IVITEATMPPGTTESLIPIL--EKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIV 191
D IV+ ++T+P T E++ IL G+K F + PE GTAI D+ ++
Sbjct: 120 DKIVVEKSTVPVKTAEAIEKILTHNSKGIK---FQILSNPEFLAEGTAIGDLFQPDRVLI 176
Query: 192 GASD----ERTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALW 247
G + ++ ++A+ +Y + I +++ +AE K+ + I+ N ++
Sbjct: 177 GGRETPEGQKAIQALKDVYAHWVPEDRILTTNLWSAELSKLAANAFLAQRISSVNAMSAL 236
Query: 248 CEEHGLDAIEIFNAANTQPYCHLHMPGA--GVGGHCIPIYPWFVINLAKKTNVRLIRTAR 305
CE G D E+ A A G GG C + ++NL +
Sbjct: 237 CEATGADVAEVSYAVGKDSRIGPKFLNASVGFGGSC---FQKDILNLVYICECNGLPEVA 293
Query: 306 E-------INDSMPRHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVI 358
E IND V V ++ + + KI +LG F+ + ++PAIDV
Sbjct: 294 EYWKQVIKINDYQKSRFVNRVVSSMFNT---VSQKKIAILGFAFKKDTGDTRETPAIDVC 350
Query: 359 RELKEWGAEVYAYDPLCTREDAERFGAKWKEDF--------------------------- 391
+ L A + YDP +E +R K D+
Sbjct: 351 QGLLGDKALLSIYDPQVQKEHIQRDLIMKKFDWDHPLHLQPKSASSAVEQVTVTSDAYEA 410
Query: 392 -KDVDAIVIVTDHREFKTLDLKEIAAEVRTKVIV-DGRNVIHPEEAKKLGFIYKGVGR 447
K+ + I+T+ EFKTLD +I ++ V DGRNV++ ++ +++GFI +G+
Sbjct: 411 TKEAHGVCILTEWDEFKTLDYNKIYDNMQKPAFVFDGRNVVNADKLREIGFIVYSIGK 468
>pir||A81290 probable UDPglucose 6-dehydrogenase (EC 1.1.1.22) Cj1441c
[imported] - Campylobacter jejuni (strain NCTC 11168)
>gi|6968870|emb|CAB73865.1| (AL139078) putative
UDP-glucose 6-dehydrogenase [Campylobacter jejuni]
Length = 393
Score = 94.4 bits (231), Expect = 2e-18
Identities = 104/412 (25%), Positives = 191/412 (46%), Gaps = 42/412 (10%)
Query: 23 IAVYGLGKMGLPLAAVFADNGA-KVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVE 81
I + G+G +GL A +F+ N +V+ +DI+E + S+NN ++ IK++ +++ +N+
Sbjct: 3 IVIVGIGYVGLANAILFSKNNENEVVLLDIDENKIQSINNHKSPIKDKL-IEKFFVQNIS 61
Query: 82 AGRLKATTDGILAAKKADVMIILVPTLADDRGNL-KLESVYDVAEKISKGLEKGDIVITE 140
+L AT++ A AD +I PT D++ N S+ +V + I K + VI +
Sbjct: 62 --KLHATSNIKEAYFNADFAVIATPTDYDEQLNFFDTRSIENVLKDI-KNINSKINVIIK 118
Query: 141 ATMPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASDERTLE 200
+T+P G T+++ S + +PE G+A+ D YP + D+ L
Sbjct: 119 STVPIGYTKTIKQKFNMSNI-------VFSPEFLREGSALYD--SLYPSRIIIGDKSVLG 169
Query: 201 AVIG--IYETINRKGV-IPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIE 257
IG + I +K V I AE+VK+F Y + + NE+ + +H L++ +
Sbjct: 170 KTIGDLFLKNIEKKNVDIFYMDSDEAESVKLFSNTYLAMRVGFFNEVDSYARKHNLNSAD 229
Query: 258 IFN--AANTQPYCHLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREINDSMPRHV 315
I +A+ + + + P G GG+C+P K +L+ I +S+ + +
Sbjct: 230 IIKGISADDRIGKYYNNPSFGYGGYCLP-----------KDTKQLLANFYNIPNSLIKAI 278
Query: 316 VELTVRALNDAGKPMKGSKILVLG---LTFRGGVKEFTKSPAIDVIRELKEWGA--EVYA 370
VE + + K +LG L + F S ID+I+ L+E+ + E+
Sbjct: 279 VETNEIRKKFITQLILEKKPNILGIYRLIMKQNSDNFRNSVIIDIIKYLQEYNSNIELII 338
Query: 371 YDPLCTREDAERFGAKWKEDFK----DVDAIVIVTDHREFKTLDLKEIAAEV 418
Y+PL ++ + K + DF VD I+ + K + K +A+V
Sbjct: 339 YEPLV--KEKKFLNIKVENDFNVFGAKVDLIIANRFDDKLKEIKDKVFSADV 388
>sp|O86422|UDG_PSEAE UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|3559950|emb|CAA09327.1| (AJ010734)
UDP-glucose 6-dehydrogenase [Pseudomonas aeruginosa]
Length = 452
Score = 94.0 bits (230), Expect = 3e-18
Identities = 93/351 (26%), Positives = 156/351 (43%), Gaps = 23/351 (6%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
+ V G G +GL AA FA+ G +V V+ + V + GE I E PGL+ +++ ++A
Sbjct: 3 LCVIGAGYVGLVTAACFAEMGNQVRCVERDRERVARLRRGEMPIYE-PGLESILRDQLDA 61
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITEAT 142
RL T A+V++I V T + G+ L V VAE++ L + IV+ ++T
Sbjct: 62 ARLTFTASLAEGLADAEVVLIAVGTPCGEDGSADLSHVLAVAEQLGAQLRQACIVVNKST 121
Query: 143 MPPGTTESLIPILEKSGL----KLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASDERT 198
+P GT E + I+ + GL K +A PE G+A+ D I+G+++ +
Sbjct: 122 VPVGTAERVEEII-RLGLARRRKRFRVAVASNPEFLKEGSAVDDFRRPDRVIIGSAETQA 180
Query: 199 LEAVIGIYETI--NRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAI 256
E + +Y N + V+ M + AE K + I+ NE+A C G+D
Sbjct: 181 GETLRQLYAPFLRNHERVLLMGR-REAEFSKYAANAFLATKISFMNEMAGLCALTGVDIE 239
Query: 257 EIFNAANTQPYCHLHM--PGAGVGGHCIPIYPWFVINLAKKTNV-RLIRTAREINDSMPR 313
++ + H G G GG C P +I A++ I A E ++ +
Sbjct: 240 DVRRGMGSDKRIGTHFIYAGCGYGGSCFPKDVRALIRSAEQQGYDSQILRAVEARNARQK 299
Query: 314 HVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEW 364
++ T+ L +G + + GL F+ P D +RE + W
Sbjct: 300 ELLFETLGELFQG--RWQGRTVALWGLAFK---------PGTDDLRERRAW 339
>gi|4507813 UDP-glucose dehydrogenase [Homo sapiens]
>gi|11435916|ref|XP_003427.1| UDP-glucose dehydrogenase
[Homo sapiens] >gi|6175086|sp|O60701|UGDH_HUMAN
UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE)
(UDP-GLCDH) (UDPGDH) >gi|3127127|gb|AAC36095.1|
(AF061016) UDP-glucose dehydrogenase [Homo sapiens]
>gi|3452405|emb|CAA07609.1| (AJ007702) UDPglucose
dehydrogenase [Homo sapiens] >gi|7025909|emb|CAB75891.1|
(AJ272274) UDP-glucose dehydrogenase [Homo sapiens]
Length = 494
Score = 93.2 bits (228), Expect = 5e-18
Identities = 112/463 (24%), Positives = 195/463 (41%), Gaps = 43/463 (9%)
Query: 23 IAVYGLGKMGLPLAAVFADN--GAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNV 80
I G G +G P +V A +V VD+NE +N+ N+ I E PGL E+V+ +
Sbjct: 7 ICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYE-PGLKEVVE-SC 64
Query: 81 EAGRLKATTDGILAAKKADVMIILVPTLADDRGNLK-----LESVYDVAEKISKGLEKGD 135
L +T+ A K+AD++ I V T G K L+ + A +I +
Sbjct: 65 RGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYK 124
Query: 136 IVITEATMPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASD 195
IV ++T+P ES+ I + + + + PE GTAI+D+ ++G +
Sbjct: 125 IVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLIGGDE 184
Query: 196 ----ERTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEH 251
+R ++A+ +YE + I ++ ++E K+ + I+ N ++ CE
Sbjct: 185 TPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLAANAFLAQRISSINSISALCEAT 244
Query: 252 GLDAIEIFNAANTQPYC--HLHMPGAGVGGHCIPIYPWFVINLAKKTNV----RLIRTAR 305
G D E+ A G GG C ++ L + N+ R +
Sbjct: 245 GADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYWQQVI 304
Query: 306 EINDSMPRHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWG 365
++ND R R ++ + KI +LG F+ + +S +I + + L + G
Sbjct: 305 DMNDYQRRRFAS---RIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMDEG 361
Query: 366 AEVYAYDPLCTRE---------------DAERFGAKWKEDFKDVD---AIVIVTDHREFK 407
A ++ YDP RE R K+ ++ D A+VI T+ FK
Sbjct: 362 AHLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKDPYEACDGAHAVVICTEWDMFK 421
Query: 408 TLDLKEIAAE-VRTKVIVDGRNVIH--PEEAKKLGFIYKGVGR 447
LD + I + ++ I DGR V+ E + +GF + +G+
Sbjct: 422 ELDYERIHKKMLKPAFIFDGRRVLDGLHNELQTIGFQIETIGK 464
>sp|P12378|UGDH_BOVIN UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|3747091|gb|AAC64183.1| (AF095792)
UDP-glucose dehydrogenase [Bos taurus]
Length = 494
Score = 93.2 bits (228), Expect = 5e-18
Identities = 113/463 (24%), Positives = 195/463 (41%), Gaps = 43/463 (9%)
Query: 23 IAVYGLGKMGLPLAAVFADN--GAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNV 80
I G G +G P +V A +V VDINE +N+ N+ I E PGL E+V+ +
Sbjct: 7 ICCIGAGYVGGPTCSVIAHMCPEIRVTVVDINESRINAWNSPTLPIYE-PGLKEVVE-SC 64
Query: 81 EAGRLKATTDGILAAKKADVMIILVPTLADDRGNLK-----LESVYDVAEKISKGLEKGD 135
L +T+ A K+AD++ I V T G K L+ + A +I +
Sbjct: 65 RGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSHGYK 124
Query: 136 IVITEATMPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASD 195
IV ++T+P ES+ I + + + + PE GTAI+D+ ++G +
Sbjct: 125 IVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLIGGDE 184
Query: 196 ----ERTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEH 251
+R ++A+ +YE + I ++ ++E K+ + I+ N ++ CE
Sbjct: 185 TPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLTANAFLAQRISSINSISALCEAT 244
Query: 252 GLDAIEIFNAANTQPYC--HLHMPGAGVGGHCIPIYPWFVINLAKKTNV----RLIRTAR 305
G D E+ A G GG C ++ L + N+ R +
Sbjct: 245 GADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYWQQVI 304
Query: 306 EINDSMPRHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWG 365
++ND R R ++ + KI +LG F+ + +S +I + + L + G
Sbjct: 305 DMNDYQRRRFAS---RIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMDEG 361
Query: 366 AEVYAYDPLCTRE---------------DAERFGAKWKEDFKDVD---AIVIVTDHREFK 407
A ++ YDP RE R K+ ++ D A+VI T+ FK
Sbjct: 362 AHLHIYDPKVPREQIVVDLSHPGVSKDDQVARLVTISKDPYEACDGAHAVVICTEWDMFK 421
Query: 408 TLDLKEIAAE-VRTKVIVDGRNVIH--PEEAKKLGFIYKGVGR 447
LD + I + ++ I DGR V+ E + +GF + +G+
Sbjct: 422 ELDYERIHKKMLKPAFIFDGRRVLDGLHNELQTIGFQIETIGK 464
>sp|O70199|UGDH_RAT UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|3133257|dbj|BAA28215.1| (AB013732)
UDP-glucose dehydrogeanse [Rattus norvegicus]
Length = 493
Score = 92.1 bits (225), Expect = 1e-17
Identities = 112/463 (24%), Positives = 194/463 (41%), Gaps = 43/463 (9%)
Query: 23 IAVYGLGKMGLPLAAVFADN--GAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNV 80
I G G +G P +V A +V VD+NE +N+ N+ I E PGL E+V+ +
Sbjct: 7 ICCIGAGYVGGPTCSVIARMCPEIRVTVVDVNEARINAWNSPTLPIYE-PGLKEVVE-SC 64
Query: 81 EAGRLKATTDGILAAKKADVMIILVPTLADDRGNLK-----LESVYDVAEKISKGLEKGD 135
L +T+ A ++AD++ I V T G K L+ + A +I +
Sbjct: 65 RGKNLFFSTNIDDAIREADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYK 124
Query: 136 IVITEATMPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASD 195
IV ++T+P ES+ I + + + + PE GTAI+D+ ++G +
Sbjct: 125 IVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLIGGDE 184
Query: 196 ----ERTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEH 251
+R ++A+ +YE K I ++ ++E K+ + I+ N ++ CE
Sbjct: 185 TPEGQRAVQALCAVYEHWVPKEKILTTNTWSSELSKLAANAFLAQRISSINSISALCEST 244
Query: 252 GLDAIEIFNAANTQPYC--HLHMPGAGVGGHCIPIYPWFVINLAKKTNV----RLIRTAR 305
G D E+ A G GG C ++ L + N+ R +
Sbjct: 245 GADVEEVATAIGMDQRIGNKFLKASVGFGGGCFQKDVLNLVYLCEALNLPEVARYWQQVI 304
Query: 306 EINDSMPRHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWG 365
++ND R R ++ + KI +LG F+ + +S +I + + L + G
Sbjct: 305 DMNDYQRRRFAS---RIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMDEG 361
Query: 366 AEVYAYDPLCTRE---------------DAERFGAKWKEDFKDVD---AIVIVTDHREFK 407
A ++ YDP RE R K+ ++ D A+VI T+ FK
Sbjct: 362 AHLHIYDPKVPREQIVVDLSHPGVSADDQVSRLVTISKDPYEACDGAHALVICTEWDMFK 421
Query: 408 TLDLKEIAAE-VRTKVIVDGRNVIH--PEEAKKLGFIYKGVGR 447
LD + I ++ I DGR V+ E + +GF + +G+
Sbjct: 422 ELDYERIHKRMLKPAFIFDGRRVLDGLHNELQTIGFQIETIGK 464
>gb|AAD50493.1|AF172324_11 (AF172324) UDP-Glc-6-dehydrogenase Ugd [Escherichia coli]
Length = 388
Score = 92.1 bits (225), Expect = 1e-17
Identities = 96/409 (23%), Positives = 177/409 (42%), Gaps = 39/409 (9%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
I + G G +GL + A N +V+ +DI + V+ +N ++ I ++ + L K++
Sbjct: 3 ITISGTGYVGLSNGILIAQNH-EVVALDIVQAKVDMLNKKQSPIVDKEIEEYLATKDLN- 60
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITEAT 142
+ATTD A K AD +II PT D + N S + + + ++I ++T
Sbjct: 61 --FRATTDKYDAYKNADYVIIATPTDYDPKTNYFNTSSVEAVIRDVTEINPNAVMIIKST 118
Query: 143 MPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASDERTLEAV 202
+P G TES I E+ G++ + +PE G A+ D ++G +R
Sbjct: 119 IPVGFTES---IKERFGIE----NVIFSPEFLREGKALYDNLHPSRIVIGEQSDRAERFA 171
Query: 203 IGIYETINRKGV-IPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIEIFNA 261
+ E ++ + I + AEA+K+F Y + +A NEL + E GL++ +I
Sbjct: 172 ALLQEGAIKQDIPILFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLNSRQIIEG 231
Query: 262 ANTQPYC--HLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREINDSMPRHVVELT 319
P H + P G GG+C+P K +L+ + + +++ +V+
Sbjct: 232 VCLDPRIGNHYNNPSFGYGGYCLP-----------KDTKQLLANYQSVPNNLISAIVDAN 280
Query: 320 VRALNDAGKPMKGSKILVLG---LTFRGGVKEFTKSPAIDVIRELKEWGAEVYAYDPLCT 376
+ + K V+G L + G S +++ +K V Y+P
Sbjct: 281 RTRKDFIADSILARKPKVVGVYRLIMKSGSDNIRASSIQGIMKRIKAKCVPVIVYEPAMK 340
Query: 377 REDAERFGAKWKEDFKDVDAIV----IVTDHREFKTLDLKEIAAEVRTK 421
+D R +D+DA V ++ +R + DL ++A +V T+
Sbjct: 341 EDDFFR-----SRVVRDLDAFVQEADVIISNR--MSADLADVADKVYTR 382
>pir||JE0353 uridine diphosphoglucose dehydrogenase (EC 1.-.-.-) - human
Length = 494
Score = 91.3 bits (223), Expect = 2e-17
Identities = 112/463 (24%), Positives = 195/463 (41%), Gaps = 43/463 (9%)
Query: 23 IAVYGLGKMGLPLAAVFADN--GAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNV 80
I G G +G P +V A +V D+NE +N+ N+ I E PGL E+V+ +
Sbjct: 7 ICCIGAGYVGGPTCSVIAHMCPEIRVTRRDVNESRINAWNSPTLPIYE-PGLKEVVE-SC 64
Query: 81 EAGRLKATTDGILAAKKADVMIILVPTLADDRGNLK-----LESVYDVAEKISKGLEKGD 135
L +T+ A K+AD++ I V T G K L+ + A +I +
Sbjct: 65 RGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYK 124
Query: 136 IVITEATMPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASD 195
IV ++T+P ES+ I + + + + PE GTAI+D+ ++G +
Sbjct: 125 IVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLIGGDE 184
Query: 196 ----ERTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEH 251
+R ++A+ +YE + I ++ ++E K+ + I+ N ++ CE
Sbjct: 185 TPEGQRAVQALCAVYEHEVPRERILTTNTWSSELSKLAANAFLAQRISSINSISALCEAT 244
Query: 252 GLDAIEIFNAANTQPYC--HLHMPGAGVGGHCIPIYPWFVINLAKKTNV----RLIRTAR 305
G D E+ A G GG C ++ L + N+ R +
Sbjct: 245 GADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYWQQVI 304
Query: 306 EINDSMPRHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWG 365
++ND R + AL + + KI +LG F+ + +S +I + + L + G
Sbjct: 305 DMNDYQRRRFASRIIDALFNT---VTDKKIAILGFAFKKDTGDTRESSSIYISKYLMDEG 361
Query: 366 AEVYAYDPLCTRE---------------DAERFGAKWKEDFKDVD---AIVIVTDHREFK 407
A ++ YDP RE R K+ ++ D A+VI T+ FK
Sbjct: 362 AHLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKDPYEACDGAHAVVICTEWDMFK 421
Query: 408 TLDLKEIAAE-VRTKVIVDGRNVIH--PEEAKKLGFIYKGVGR 447
LD + I + ++ I DGR V+ E + +GF + +G+
Sbjct: 422 ELDYERIHKKMLKPAFIFDGRRVLDGLHNELQTIGFQIETIGK 464
>pir||A54926 UDPglucose 6-dehydrogenase (EC 1.1.1.22) - bovine
>gi|806944|gb|AAB32227.1| UDP-glucose dehydrogenase,
UDPGDH=52 kda subunit {EC 1.1.1.22} [cattle, liver,
Peptide, 468 aa]
Length = 468
Score = 90.9 bits (222), Expect = 3e-17
Identities = 113/463 (24%), Positives = 197/463 (42%), Gaps = 44/463 (9%)
Query: 23 IAVYGLGKMGLPLAAVFADN--GAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNV 80
I G G +G P +V A +V VDINE +N+ N+ I E PGL E+V+ +
Sbjct: 7 ICCIGAGYVGGPTCSVIAHMCPEIRVTVVDINESRINAWNSPTLPIYE-PGLKEVVE-SC 64
Query: 81 EAGRLKATTDGILAAKKADVMIILVPTLADDRGNLK-----LESVYDVAEKISKGLEKGD 135
L +T+ A K+AD++ I V T G K L+ + A +I +
Sbjct: 65 RGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSHGYK 124
Query: 136 IVITEATMPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASD 195
IV ++T+P ES+ I + + + +++ PE GTAI+D+ ++G +
Sbjct: 125 IVTEKSTVPVRAAESIRRIFDANTKPNLNLQVSN-PEFLAEGTAIKDLKNPDRVLIGGDE 183
Query: 196 ----ERTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEH 251
+R ++A+ +YE + I ++ ++E K+ + I+ N ++ CE
Sbjct: 184 TPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLTANAFLAQRISSINSISALCEAT 243
Query: 252 GLDAIEIFNAANTQPYC--HLHMPGAGVGGHCIPIYPWFVINLAKKTNV----RLIRTAR 305
G D E+ A G GG C ++ L + N+ R +
Sbjct: 244 GADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYWQQVI 303
Query: 306 EINDSMPRHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWG 365
++ND R R ++ + KI +LG F+ + +S +I + + L + G
Sbjct: 304 DMNDYQRRRFAS---RIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMDEG 360
Query: 366 AEVYAYDPLCTRE---------------DAERFGAKWKEDFKDVD---AIVIVTDHREFK 407
A ++ YDP RE R K+ ++ D A+VI T+ FK
Sbjct: 361 AHLHIYDPKVPREQIVVDLSHPGVSKDDQVARLVTISKDPYEACDGAHAVVICTEWDMFK 420
Query: 408 TLDLKEIAAE-VRTKVIVDGRNVIH--PEEAKKLGFIYKGVGR 447
LD + I + ++ I DGR V+ E + +GF + +G+
Sbjct: 421 ELDYERIHKKMLKPAFIFDGRRVLDGLHNELQTIGFQIETIGK 463
>gi|6678499 UDP-glucose dehydrogenase [Mus musculus]
>gi|6136117|sp|O70475|UGDH_MOUSE UDP-GLUCOSE
6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|3127129|gb|AAC36096.1| (AF061017)
UDP-glucose dehydrogenase [Mus musculus]
Length = 493
Score = 90.9 bits (222), Expect = 3e-17
Identities = 111/463 (23%), Positives = 194/463 (40%), Gaps = 43/463 (9%)
Query: 23 IAVYGLGKMGLPLAAVFADN--GAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNV 80
I G G +G P +V A +V VD+NE +N+ N+ I E PGL E+V+ +
Sbjct: 7 ICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNEARINAWNSPTLPIYE-PGLKEVVE-SC 64
Query: 81 EAGRLKATTDGILAAKKADVMIILVPTLADDRGNLK-----LESVYDVAEKISKGLEKGD 135
L +T+ A ++AD++ I V T G K L+ + A +I +
Sbjct: 65 RGKNLFFSTNIDDAIREADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYK 124
Query: 136 IVITEATMPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASD 195
IV ++T+P ES+ I + + + + PE GTAI+D+ ++G +
Sbjct: 125 IVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLIGGDE 184
Query: 196 ----ERTLEAVIGIYETINRKGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEH 251
++ + A+ +YE K I ++ ++E K+ + I+ N ++ CE
Sbjct: 185 TPEGQKAVRALCAVYEHWVPKEKILTTNTWSSELSKLAANAFLAQRISSINSISALCEAT 244
Query: 252 GLDAIEIFNAANTQPYC--HLHMPGAGVGGHCIPIYPWFVINLAKKTNV----RLIRTAR 305
G D E+ A G GG C ++ L + N+ R +
Sbjct: 245 GADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYWQQVI 304
Query: 306 EINDSMPRHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWG 365
++ND R R ++ + KI +LG F+ + +S +I + + L + G
Sbjct: 305 DMNDYQRRRFAS---RIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMDEG 361
Query: 366 AEVYAYDPLCTRE---------------DAERFGAKWKEDFKDVD---AIVIVTDHREFK 407
A ++ YDP RE R K+ ++ D A+VI T+ FK
Sbjct: 362 AHLHIYDPKVPREQIVVDLSHPGVSADDQVSRLVTISKDPYEACDGAHALVICTEWDMFK 421
Query: 408 TLDLKEIAAE-VRTKVIVDGRNVIH--PEEAKKLGFIYKGVGR 447
LD + I + ++ I DGR V+ E + +GF + +G+
Sbjct: 422 ELDYERIHKKMLKPAFIFDGRRVLDGLHSELQTIGFQIETIGK 464
>pir||F82417 UDP-glucose 6-dehydrogenase VCA0780 [imported] - Vibrio cholerae
(group O1 strain N16961) >gi|9658204|gb|AAF96678.1|
(AE004406) UDP-glucose 6-dehydrogenase [Vibrio cholerae]
Length = 388
Score = 90.9 bits (222), Expect = 3e-17
Identities = 103/414 (24%), Positives = 184/414 (43%), Gaps = 49/414 (11%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
IA+ G G +GL + A + +V+ +DI V +N+ + I + P ++ ++ +
Sbjct: 3 IAIAGTGYVGLSNGILLAQHN-EVVALDIVVSRVEQLNDKISPIAD-PEIESFLQH--QP 58
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGN----LKLESVYDVAEKISKGLEKGDIVI 138
+AT D A + A ++I PT D + N +E+V D I+ I++
Sbjct: 59 LNFRATCDKRDAYQDAQFVVIATPTDYDPQTNHFDTRTVEAVIDDVLAINPQA----IMV 114
Query: 139 TEATMPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPK--IVGASDE 196
++T+P G T+ + +L L +PE G A+ D YP IVG E
Sbjct: 115 IKSTVPVGYTKRIKQ-------RLCCNNLIFSPEFLREGRALYD--NLYPSRIIVGEKSE 165
Query: 197 RTLEAVIGIYETINRKGVIP--MSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLD 254
R +A + +K IP ++ AEAVK+F Y + ++ NEL + E HGLD
Sbjct: 166 RG-QAFATLLAQGAKKMDIPILLTHSTEAEAVKLFSNTYLAMRVSFFNELDTYAETHGLD 224
Query: 255 AIEIFNAANTQPYC--HLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREINDSMP 312
+I P H + P G GG+C+P K +L+R ++ +++
Sbjct: 225 TKQIIEGVGLDPRIGNHYNNPSFGYGGYCLP-----------KDTRQLLRNFEDVPNNLI 273
Query: 313 RHVVELTVRALNDAGKPMKGSKILVLG---LTFRGGVKEFTKSPAIDVIRELKEWGAEVY 369
R +V+ + + V+G L + G F S + +++ +K G EV
Sbjct: 274 RAIVDANTTRKDHIAFSILNRNPKVVGIYRLIMKSGSDNFRASSILGIMKRIKAQGVEVV 333
Query: 370 AYDPLCTREDAERFGAKWKEDFKDVDAI--VIVTDHREFKTLDLKEIAAEVRTK 421
Y+P+ ++ +G+ D A+ VIVT+ R +L+++A ++ T+
Sbjct: 334 IYEPVL--NESTFYGSPVIRDLAQFKAMAEVIVTNRR---VAELEDVAEKIYTR 382
>gb|AAF04239.1|AF093225_1 (AF093225) Vps21 [Vibrio cholerae]
Length = 106
Score = 89.7 bits (219), Expect = 6e-17
Identities = 44/98 (44%), Positives = 62/98 (62%), Gaps = 1/98 (1%)
Query: 212 KGVIPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIEIFNAANTQPYCHLH 271
KG +++ + AE K+ E +RDVNIA ANEL+L C + ++ E+ AN P +
Sbjct: 10 KGECIVTNARTAEMAKLTENSFRDVNIAFANELSLVCNKLKINVWELIRLANRHPRVSIL 69
Query: 272 MPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREIND 309
PG GVGGHCI + PWF++N + +LIRTARE+ND
Sbjct: 70 NPGPGVGGHCIAVDPWFIVN-SCPDEAQLIRTAREVND 106
>emb|CAB43615.1| (AJ239004) uridine diphosphate glucose dehydrogenase [Streptococcus
pneumoniae]
Length = 412
Score = 89.3 bits (218), Expect = 8e-17
Identities = 100/416 (24%), Positives = 176/416 (42%), Gaps = 42/416 (10%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
IAV G G +GL +A + A + +VI VDI V +N ++ I+++ L +K++
Sbjct: 3 IAVTGTGYVGLSIAVLLAQHH-QVIAVDIIPEKVELINQRKSPIQDDYIEKYLAEKDLN- 60
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGNL-KLESVYDVAEKISKGLEKGDIVITEA 141
L AT D A K AD ++I PT D + N +V V E + K I++ ++
Sbjct: 61 --LVATLDAKEAYKDADFVVIAAPTNYDPKKNFFDTSAVESVIETVLK-YNPDAIMVIKS 117
Query: 142 TMPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASDERTLEA 201
T+P G TES + K + +PE A+ D YP + ++ E
Sbjct: 118 TVPVGYTES-------ARKKFQTENILFSPEFLRESKALYD--NLYPSRIILGTDKNNER 168
Query: 202 VIGIYETINRKGVIPMSSIKA-----------AEAVKVFEGIYRDVNIALANELALWCEE 250
++ + ET G++ ++K AEAVK+F Y + ++ NEL + E
Sbjct: 169 LVSVAETF--AGLLQEGALKEDIDTLYMGFTEAEAVKLFANTYLALRVSYFNELDTYSEM 226
Query: 251 HGLDAIEIFNAANTQPY--CHLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREIN 308
GLD I + P H + P G GG+C+P ++ + LI N
Sbjct: 227 KGLDTQAIIDGVGLDPRIGSHYNNPSFGYGGYCLPKDTKQLLANYEDVPEELIGAIVRSN 286
Query: 309 DSMPRHVVELTVRALNDAGKPM------KGSKILVLG---LTFRGGVKEFTKSPAIDVIR 359
+ + + ++ ++ + K +++G LT + F +S +++
Sbjct: 287 STRKDFIADQVLKMVDSYDYSAHNVFNERVEKDIIIGIYRLTMKSNSDNFRQSSIQGIMK 346
Query: 360 ELKEWGAEVYAYDPLCTREDAERFGAKWKEDFKDVDAI--VIVTDHREFKTLDLKE 413
+K G V Y+P + FG+ D ++ + IV + + D+KE
Sbjct: 347 RIKAKGVRVVIYEP-TLESGSTFFGSSIINDLEEFKRLSNAIVANRYDNSLEDVKE 401
>emb|CAB05929.1| (Z83335) uridine diphosphate glucose dehydrogenase [Streptococcus
pneumoniae]
Length = 410
Score = 88.9 bits (217), Expect = 1e-16
Identities = 103/392 (26%), Positives = 175/392 (44%), Gaps = 40/392 (10%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
IAV G G +GL +A + A + +V+ VDI V +N K+ P D+ ++K +
Sbjct: 3 IAVAGTGYVGLFIAILLAQHH-QVVAVDIIPEKVELINK-----KKSPIQDDYIEKYLAE 56
Query: 83 GRLK--ATTDGILAAKKADVMIILVPTLADDRGNL-KLESVYDVAEKISKGLEKGDIVIT 139
L AT + A + AD ++I PT D + N SV V E + K I+I
Sbjct: 57 KELNFVATLNAEEAYENADFIVIAAPTNYDPKKNFFDTSSVEAVIEAVMK-YNPDAIIII 115
Query: 140 EATMPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPK--IVGAS-DE 196
++T+P G T+S+ K + +PE A+ D YP I+G D+
Sbjct: 116 KSTVPVGYTKSV-------RRKFLTDNIMFSPEFLRESKALYD--NLYPSRIIIGTDKDD 166
Query: 197 RTLEAVIGIYETINRKGVIPMS------SIKAAEAVKVFEGIYRDVNIALANELALWCEE 250
+ L I+ + ++G + + AEAVK+F Y + ++ NEL + E
Sbjct: 167 KDLVKSAEIFVKMLQEGAVKENIETLYMDFTEAEAVKLFANTYLALRVSYFNELDTYSEM 226
Query: 251 HGLDAIEIFNAANTQPY--CHLHMPGAGVGGHCIPIYPWFVI----NLAKKTNVRLIRTA 304
GLD I + P H + P G GG+C+P ++ ++ ++ ++++
Sbjct: 227 KGLDTQAIIDGVCLDPRIGSHYNNPSFGYGGYCLPKDTKQLLANYSDVPQEMITAIVQSN 286
Query: 305 REINDSMPRHVVELTVRAL-NDAGKPMKGSKILV--LGLTFRGGVKEFTKSPAIDVIREL 361
R D + +++L + ND KP K +I+V LT + F +S +++ L
Sbjct: 287 RTRKDYIADRILDLAGSYVGNDFYKPDKEKEIVVGIYRLTMKSNSDNFRQSSIQGIMKRL 346
Query: 362 KEWGAEVYAYDPLCTREDAERF-GAKWKEDFK 392
K G + Y+P T E F G++ DF+
Sbjct: 347 KAKGVTIIIYEP--TLESGTTFYGSQVVNDFE 376
>sp|Q58454|YA54_METJA HYPOTHETICAL PROTEIN MJ1054 >gi|2129344|pir||E64431 UDPglucose
6-dehydrogenase (EC 1.1.1.22) (intein-containing) -
Methanococcus jannaschii >gi|1591706|gb|AAB99056.1|
(U67548) UDP-glucose dehydrogenase, putative
[Methanococcus jannaschii]
Length = 895
Score = 88.5 bits (216), Expect = 1e-16
Identities = 75/269 (27%), Positives = 127/269 (46%), Gaps = 16/269 (5%)
Query: 21 VTIAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNV 80
+ I+V G G +GL A A+ G V+G+DI+E V ++N GE + EE GL+ L+KK+V
Sbjct: 1 MNISVIGTGYVGLIQAVGLAEFGFDVVGIDIDESKVKALNRGECPLYEE-GLEGLLKKHV 59
Query: 81 EAGRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGD--IVI 138
+ T K +DV+ + V T D GN L ++ EKI + ++K D +++
Sbjct: 60 --NKNLTFTTSYKPIKDSDVIFLCVGTPQDKDGNADLRFLFSAVEKIKETIDKEDYKVIV 117
Query: 139 TEATMPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVG---ASD 195
++T+P GT + K LK + + PE G A+ D I+G ++
Sbjct: 118 IKSTVPVGTNRRV-----KELLKDYNVDVVSNPEFLREGIAVYDFFNPERVILGFENLNN 172
Query: 196 ERTLEAVIGIYETINRKGV-IPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLD 254
++ +E + +Y+ K + +++ + AE +K + I+ NELA ++ D
Sbjct: 173 KKPIEIMEEVYKYFKDKNIPFVITNWETAELIKYASNAFLATKISFINELAKLSDKVKAD 232
Query: 255 AIEIFNAANTQPYCHLHMPGAGV--GGHC 281
I A P AG+ GG C
Sbjct: 233 IKTISYAMGLDPRIGNKFLNAGIGYGGSC 261
>sp|Q47329|UDG5_ECOLI UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|2126103|pir||S70197 UDP-glucose
dehydrogenase - Escherichia coli
>gi|735963|emb|CAA54708.1| (X77617) UDP-glucose
dehydrogenase [Escherichia coli]
Length = 392
Score = 87.4 bits (213), Expect = 3e-16
Identities = 82/359 (22%), Positives = 156/359 (42%), Gaps = 22/359 (6%)
Query: 19 GDVTIAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKK 78
G + I V G G +GL + A N +V+ D +++ V+ +N+ + I+++ + L K
Sbjct: 3 GTLKITVSGAGYVGLSNGILMAQNH-EVVAFDTHQKKVDLLNDKLSPIEDKEIENYLSTK 61
Query: 79 NVEAGRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVI 138
+ +ATT+ A K A+ +II PT D N S + + + I++
Sbjct: 62 ILN---FRATTNKYEAYKNANYVIIATPTNYDPGSNYFDTSSVEAVIRDVTEINPNAIMV 118
Query: 139 TEATMPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASDERT 198
++T+P G T+++ LG + +PE G A+ D I+G ER
Sbjct: 119 VKSTVPVGFTKTIKE-------HLGINNIIFSPEFLREGRALYDNLHPSRIIIGECSERA 171
Query: 199 LEAVIGIYETINRKGV-IPMSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIE 257
+ E ++ + + + AEA+K+F Y + +A NEL + E GL+ +
Sbjct: 172 ERLAVLFQEGAIKQNIPVLFTDSTEAEAIKLFSNTYLAMRVAFFNELDSYAESFGLNTRQ 231
Query: 258 IFNAANTQPYC--HLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREINDSMPRHV 315
I + P + + P G GG+C+P ++ + +LI + N + +
Sbjct: 232 IIDGVCLDPRIGNYYNNPSFGYGGYCLPKDTKQLLANYQSVPNKLISAIVDANRTRKDFI 291
Query: 316 VELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYAYDPL 374
+ ++ + + V L + G F S + +I+ +K+ G +V Y+PL
Sbjct: 292 TNVILK--------HRPQVVGVYRLIMKSGSDNFRDSSILGIIKRIKKKGVKVIIYEPL 342
>sp|Q04873|UDG_SALTY UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|485529|pir||S33671 hypothetical protein
(cld 3' region) - Salmonella choleraesuis
>gi|46959|emb|CAA78945.1| (Z17278) putative
UDP-D-glucose dehydrogenase [Salmonella enterica]
Length = 388
Score = 87.0 bits (212), Expect = 4e-16
Identities = 100/407 (24%), Positives = 174/407 (42%), Gaps = 48/407 (11%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
I + G G +GL + A + V+ +DI V +N+ + I ++ L + N+
Sbjct: 3 ITISGTGYVGLSNGLLIAQHH-DVVALDIVPSRVELLNDRISPIVDKEIQQFLKEDNI-- 59
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGN-LKLESVYDVAEKISKGLEKGDIVITEA 141
R +AT D A + AD +II PT D + N SV V + + + ++I ++
Sbjct: 60 -RFRATLDKFDAYQNADYVIIATPTDYDPKTNYFNTSSVESVMQDVIS-INPAAVMIIKS 117
Query: 142 TMPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPK--IVGASDERTL 199
T+P G T ++ K + +PE G A+ D YP ++G ER
Sbjct: 118 TVPVGFTAAMRQ-------KFATENIIFSPEFLREGKALYD--NLYPSRIVIGEQSERAR 168
Query: 200 EAVIGIYETINRKGVIPM-SSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIEI 258
E + E ++ + + + AEA+K+F Y + +A NEL + E GL+ +I
Sbjct: 169 EFAALLQEGAIKQEIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAETLGLNTRQI 228
Query: 259 FNAANTQPYC--HLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREINDSMPRHVV 316
P H + P G GG+C+P K +L+ + S+P +++
Sbjct: 229 IEGVCLDPRIGNHYNNPSFGYGGYCLP-----------KDTKQLLANYQ----SVPNNII 273
Query: 317 ELTVRA-------LNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVY 369
V A + DA K + + L + G F S +++ +K G EV
Sbjct: 274 SAIVEANRTRKDFIADAILARKPKVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVI 333
Query: 370 AYDPLCTREDAERFGAKWKED---FKDVDAIVIVTDHREFKTLDLKE 413
Y+P+ E+ F ++ + D FK A VI+++ + LD+ E
Sbjct: 334 IYEPV--MEEDTFFNSRLERDLHCFKQ-QADVIISNRMAAELLDVAE 377
>gb|AAC45348.1| (U90519) putative UDP-glucose dehydrogenase [Escherichia coli]
Length = 388
Score = 84.3 bits (205), Expect = 3e-15
Identities = 88/368 (23%), Positives = 154/368 (40%), Gaps = 38/368 (10%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
I + G G +GL + A N +V+ +DI + V+ +N + I ++ + L +K +
Sbjct: 3 ITISGTGYVGLSNGVLIAQNH-EVVALDIVQAKVDMLNQKISPIVDKEIQEYLAEKPLN- 60
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITEAT 142
+ATTD A + AD +II PT D + N S + + + ++I ++T
Sbjct: 61 --FRATTDKHDAYRNADYVIIATPTDYDPKTNYFNTSTVEAVIRDVTEINPNAVMIIKST 118
Query: 143 MPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASDERTLEAV 202
+P G T + +LG + +PE G A+ D ++G R E
Sbjct: 119 IPVGFTRDIKE-------RLGIDNVIFSPEFLREGRALYDNLHPSRIVIGERSARA-ERF 170
Query: 203 IGIYETINRKGVIP--MSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIEIFN 260
+ + K IP + AEA+K+F Y + +A NEL + E GL++ +I
Sbjct: 171 ADLLKEGAIKQDIPTLFTDSTEAEAIKLFANTYLALRVAYFNELDSYAESQGLNSKQIIE 230
Query: 261 AANTQPYC--HLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREINDSMPRHVVEL 318
P H + P G GG+C+P K T L +S+P +++
Sbjct: 231 GVCLDPRIGNHYNNPSFGYGGYCLP----------KDTKQLLAN-----YESVPNNIIAA 275
Query: 319 TVRA-------LNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYAY 371
V A ++D+ K + V L + G F S +++ +K G V Y
Sbjct: 276 IVDANRTRKDFISDSILARKPKVVGVYRLIMKSGSDNFRASSIQGIMKRIKAKGIPVIIY 335
Query: 372 DPLCTRED 379
+P+ ++
Sbjct: 336 EPVMQEDE 343
>gb|AAD10180.1| (AF026471) Cps2K [Streptococcus pneumoniae]
Length = 412
Score = 83.5 bits (203), Expect = 4e-15
Identities = 99/417 (23%), Positives = 175/417 (41%), Gaps = 44/417 (10%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
IAV G G +GL +A + + +V+ VDI V +N ++ I+++ L KK++
Sbjct: 3 IAVAGTGYVGLSIAVLLSQQH-QVMAVDIIPEKVELINQRKSPIQDDYIEKYLAKKDLN- 60
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGNL----KLESVYDVAEKISKGLEKGDIVI 138
L AT D A + AD ++I PT D + N +ESV + A K + I++
Sbjct: 61 --LVATLDAKEAYQDADFVVIAAPTNYDPKKNFFDTSAVESVIETALKYNPDA----IMV 114
Query: 139 TEATMPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASDERT 198
++T+P G TES + K + +PE A+ D YP + ++
Sbjct: 115 IKSTVPVGYTES-------ARKKFQTENILFSPEFLRESKALYD--NLYPSRIILGTDKN 165
Query: 199 LEAVIGIYETINR---KGVIPMS------SIKAAEAVKVFEGIYRDVNIALANELALWCE 249
E ++ ET R +G + + AEAVK+F Y + ++ NEL + E
Sbjct: 166 NERLVSAAETFARLLQEGALKENIDTLYMGFTEAEAVKLFANTYLALRVSYFNELDTYSE 225
Query: 250 EHGLDAIEIFNAANTQPY--CHLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREI 307
GLD I + P H + P G GG+C+P ++ + LI
Sbjct: 226 MTGLDTQAIIDGVGLDPRIGSHYNNPSFGYGGYCLPKDTKQLLANYEDIPGELIGAIVRS 285
Query: 308 NDSMPRHVVELTVRALNDAGKPM------KGSKILVLG---LTFRGGVKEFTKSPAIDVI 358
N + + + ++ ++ + K +++G LT + F +S ++
Sbjct: 286 NSTRKDFIADQVLKMVDYYDYSAHNIFDERVEKDIIIGIYRLTMKSNSDNFRQSSIQGIM 345
Query: 359 RELKEWGAEVYAYDPLCTREDAERFGAKWKEDFKDVDAI--VIVTDHREFKTLDLKE 413
+ +K G V Y+P + FG+ D ++ + IV + + D+KE
Sbjct: 346 KRIKAKGVRVVIYEP-TLESGSTFFGSSVINDLEEFKRLSNAIVANRYDNSLEDVKE 401
>emb|CAA79813.1| (Z21706) ORF7 [synthetic construct]
Length = 209
Score = 83.5 bits (203), Expect = 4e-15
Identities = 70/215 (32%), Positives = 100/215 (45%), Gaps = 17/215 (7%)
Query: 16 IKNGDVTIAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLD-- 73
I DV IA+ GLG +GLPLAA F +V+G D+N + + ++ + G+D
Sbjct: 2 ISKDDVKIAIIGLGYVGLPLAAEFGKI-RQVVGFDVNHKRI---------LELKEGIDVN 51
Query: 74 -ELVKKNVEAGRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLE 132
E ++ + R T I ++ + II VPT +D L + +E + K L
Sbjct: 52 LETTEEELRDARHLTFTSSIDEIRECNFYIITVPTPINDYKQPDLTPLIMASETVGKVLR 111
Query: 133 KGDIVITEATMPPG-TTESLIPILEKSGLKL--GDFGLAHAPERTMTGTAIRDITGQYPK 189
GDIV+ E+T+ PG T E +PILE+ DF + ++PER G +T K
Sbjct: 112 PGDIVVYESTVYPGCTEEECVPILERMSAMTFNKDFFVGYSPERINPGDKKYRLT-TIKK 170
Query: 190 IVGASDERTLEAVIGIYETINRKGVIPMSSIKAAE 224
I S T V IY I G SIK AE
Sbjct: 171 ITSGSTAETACLVDEIYRQIITAGTYKTESIKIAE 205
>sp|P76373|UDG_ECOLI UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|7431378|pir||C64968 hypothetical protein
b2028 - Escherichia coli (strain K-12)
>gi|1736716|dbj|BAA15868.1| (D90841) UDG protein.
[Escherichia coli] >gi|1788340|gb|AAC75089.1| (AE000294)
UDP-glucose 6-dehydrogenase [Escherichia coli K12]
Length = 388
Score = 82.7 bits (201), Expect = 8e-15
Identities = 100/415 (24%), Positives = 180/415 (43%), Gaps = 51/415 (12%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
I + G G +GL + A N +V+ +DI V +N+ + P +D+ +++ +++
Sbjct: 3 ITISGTGYVGLSNGLLIAQNH-EVVALDILPSRVAMLND-----RISPIVDKEIQQFLQS 56
Query: 83 GRL--KATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITE 140
++ AT D A + AD +II PT D + N S + K + +++ +
Sbjct: 57 DKIHFNATLDKNEAYRDADYVIIATPTDYDPKTNYFNTSSVESVIKDVVEINPYAVMVIK 116
Query: 141 ATMPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASDERTLE 200
+T+P G T ++ K + +PE G A+ D ++G ER E
Sbjct: 117 STVPVGFTAAMHK-------KYRTENIIFSPEFLREGKALYDNLHPSRIVIGERSERA-E 168
Query: 201 AVIGIYETINRKGVIPM--SSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIEI 258
+ + K IPM + AEA+K+F Y + +A NEL + E GL++ +I
Sbjct: 169 RFAALLQEGAIKQNIPMLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLNSRQI 228
Query: 259 FNAANTQPYC--HLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREINDSMPRHVV 316
P H + P G GG+C+P K +L+ + S+P +++
Sbjct: 229 IEGVCLDPRIGNHYNNPSFGYGGYCLP-----------KDTKQLLANYQ----SVPNNLI 273
Query: 317 ELTVRA-------LNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVY 369
V A + DA K + + L + G F S +++ +K G EV
Sbjct: 274 SAIVDANRTRKDFIADAILSRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVI 333
Query: 370 AYDPLCTREDAERFGAKWKED---FKDVDAIVIVTDHREFKTLDLKEIAAEVRTK 421
Y+P+ +ED+ F ++ + D FK ++I E +LK++A +V T+
Sbjct: 334 IYEPV-MKEDS-FFNSRLERDLATFKQQADVIISNRMAE----ELKDVADKVYTR 382
>gi|9632145 PBCV-1 UDP-glucose dehydrogenase [Paramecium bursaria Chlorella
virus 1] >gi|7431390|pir||T18111 probable UDPglucose
6-dehydrogenase (EC 1.1.1.22) - Chlorella virus PBCV-1
>gi|2447087|gb|AAC96945.1| (U42580) PBCV-1 UDP-glucose
dehydrogenase [Paramecium bursaria Chlorella virus 1]
Length = 389
Score = 82.3 bits (200), Expect = 1e-14
Identities = 96/373 (25%), Positives = 160/373 (42%), Gaps = 41/373 (10%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
IAV G G +G A + A +VI +DI+E V + N ++ I+++ + L K++
Sbjct: 4 IAVVGCGYVGTACAVLLAQKN-EVIVLDISEDRVQLIKNKKSPIEDKEIEEFLETKDLN- 61
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKI--SKGLEK--GDIVI 138
L ATTD +LA + A+ +II PT YDV + +K +E GD++
Sbjct: 62 --LTATTDKVLAYENAEFVIIATPT------------DYDVVTRYFNTKSVENVIGDVIK 107
Query: 139 TEATMPPGTTESLIPI--LEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYP-KIVGASD 195
T P +S IPI ++K + + +PE G A+ D YP +I+ D
Sbjct: 108 NTQTHPTIVIKSTIPIGFVDKVREQFDYQNIIFSPEFLREGRALYD--NLYPSRIIVGDD 165
Query: 196 ERTLEAVIGIYETINRKGVIPMSSI--KAAEAVKVFEGIYRDVNIALANELALWCEEHGL 253
+ ++ + P+ ++ + AEAVK+F Y + +A NEL + HG+
Sbjct: 166 SPIALKFANLLVEGSKTPLAPVLTMGTREAEAVKLFSNTYLAMRVAYFNELDTFAMSHGM 225
Query: 254 DAIEIFNAANTQPYC--HLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREINDSM 311
+A EI + +P P G G +C P ++ + +I E N++
Sbjct: 226 NAKEIIDGVTLEPRIGQGYSNPSFGYGAYCFPKDTKQLLANFEGVPQDIIGAIVESNETR 285
Query: 312 PRHVV-ELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYA 370
+V E+ R G V L + G F S +D++ L G +
Sbjct: 286 KEVIVSEVENRFPTTVG---------VYKLAAKAGSDNFRSSAIVDIMERLANKGYHIKI 336
Query: 371 YDPLCTREDAERF 383
++P T E E F
Sbjct: 337 FEP--TVEQFENF 347
>dbj|BAA77737.1| (AB008676) UDP-glucose-6-dehydrogenase [Escherichia coli]
>gi|11464509|gb|AAG35214.1| (AF176356)
UDP-glucose-6-dehydrogenase [Escherichia coli]
Length = 388
Score = 82.3 bits (200), Expect = 1e-14
Identities = 96/414 (23%), Positives = 180/414 (43%), Gaps = 49/414 (11%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
I + G G +GL + A N +V+ +DI V +N+ + P +D+ +++ +++
Sbjct: 3 ITISGTGYVGLSNGLLIAQNH-EVVALDILPSRVAMLND-----RISPIVDKEIQQFLQS 56
Query: 83 GRL--KATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITE 140
++ AT D A + AD +II PT D + N S + K + +++ +
Sbjct: 57 DKIHFNATLDKNEAYRDADYVIIATPTDYDPKTNYFNTSSVESVIKDVVEINPYAVMVIK 116
Query: 141 ATMPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASDERTLE 200
+T+P G TE++ K + +PE G A+ D ++G ER
Sbjct: 117 STVPVGFTEAMHK-------KYRTENIIFSPEFLREGKALYDNLHPSRIVIGERSERAER 169
Query: 201 AVIGIYETINRKGVIPM-SSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIEIF 259
+ E ++ + + + AEA+K+F Y + +A NEL + E GL++ +I
Sbjct: 170 FAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLNSRQII 229
Query: 260 NAANTQPYC--HLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREINDSMPRHVVE 317
P H + P G GG+C+P K +L+ + S+P +++
Sbjct: 230 EGVCLDPRIGNHYNNPSFGYGGYCLP-----------KDTKQLLANYQ----SVPNNLIS 274
Query: 318 LTVRA-------LNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYA 370
V A + DA K + + L + G F S +++ +K G EV
Sbjct: 275 AIVDANRTRKDFIADAILSRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVII 334
Query: 371 YDPLCTREDAERFGAKWKED---FKDVDAIVIVTDHREFKTLDLKEIAAEVRTK 421
Y+P+ +ED+ F ++ + D FK ++I E +L+++A +V T+
Sbjct: 335 YEPV-MKEDS-FFNSRLERDLATFKQQADVIISNRMAE----ELRDVADKVYTR 382
>sp|Q04872|UDG1_ECOLI UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|485526|pir||S33668 hypothetical protein
(gnd 3' region) - Escherichia coli
>gi|41110|emb|CAA78939.1| (Z17241) putative
UDP-D-glucose dehydrogenase [Escherichia coli]
Length = 388
Score = 81.5 bits (198), Expect = 2e-14
Identities = 98/414 (23%), Positives = 177/414 (42%), Gaps = 49/414 (11%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
I + G G +GL + A + +V+ +DI V +N K+ P +D+ +++ +
Sbjct: 3 ITISGTGYVGLSNGILIAQHH-EVVALDIVPTKVEMLNQ-----KKSPIVDKEIEEYLAT 56
Query: 83 GRL--KATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITE 140
+L +ATTD A + +II PT D + N S + + + +++ +
Sbjct: 57 KQLNFRATTDKYDAYRDGTYVIIATPTDYDPKTNYFNTSSVESVIRDVVDINPNAVMVIK 116
Query: 141 ATMPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASDERTLE 200
+T+P G T L +LG + +PE G A+ D ++G ER
Sbjct: 117 STIPVGFTNLLKE-------RLGIDNIFFSPEFLREGRALYDNLHPSRIVIGERSERAGR 169
Query: 201 AVIGIYETINRKGVIPM-SSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIEIF 259
+ E +K + + + AEA+K+F Y + +A NEL + E GL++ +I
Sbjct: 170 FAALLQEGAVKKDIPTLFTDSTEAEAIKLFANTYLALRVAYFNELDSYAESLGLNSRQII 229
Query: 260 NAANTQPYC--HLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREINDSMPRHVVE 317
P H + P G GG+C+P K T L A S+P +++
Sbjct: 230 EGVCLDPRIGNHYNNPSFGYGGYCLP----------KDTKQLLANYA-----SVPNNIIG 274
Query: 318 LTVRA-------LNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYA 370
V A + D+ K + V L + G F S +++ +K G V
Sbjct: 275 AIVDANRTRKDFIADSILARKPKVVGVYRLIMKSGSDNFRASSIQGIMKRIKAKGVPVII 334
Query: 371 YDPLCTREDAERFGAKWKED---FKDVDAIVIVTDHREFKTLDLKEIAAEVRTK 421
Y+P+ + E F ++ D FK+ +A +I+++ T +L ++A +V T+
Sbjct: 335 YEPVMVED--EFFHSRVVRDLTAFKN-EADIIISNR---MTSELADVADKVYTR 382
>gb|AAG35229.1| (AF176369) UDP-glucose-6-dehydrogenase [Escherichia coli]
Length = 388
Score = 81.1 bits (197), Expect = 2e-14
Identities = 96/414 (23%), Positives = 178/414 (42%), Gaps = 49/414 (11%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
I + G G +GL + A N +V+ +DI V +N+ + P +D+ +++ +++
Sbjct: 3 ITISGTGYVGLSNGLLIAQNH-EVVALDILPSRVAMLND-----RISPIVDKEIQQFLQS 56
Query: 83 GRL--KATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITE 140
++ AT D A + AD +II PT D + N S + K + +++ +
Sbjct: 57 DKIHFNATLDKNEAYRDADYVIIATPTDYDPKTNYFNTSSVESVIKDVVEINPYAVMVIK 116
Query: 141 ATMPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASDERTLE 200
+T+P G TE++ K + +PE G A+ D ++G ER
Sbjct: 117 STVPVGFTEAMHK-------KYRTENIIFSPEFLREGKALYDNLHPSRIVIGERSERAER 169
Query: 201 AVIGIYETINRKGVIPM-SSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIEIF 259
+ E ++ + + + AEA+K+F Y + +A NEL + E GL+ +I
Sbjct: 170 FAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLNTRQII 229
Query: 260 NAANTQPYC--HLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREINDSMPRHVVE 317
P H + P G GG+C+P K +L+ + S+P +++
Sbjct: 230 EGVCLDPRIGNHYNNPSFGYGGYCLP-----------KDTKQLLANYQ----SVPNNLIS 274
Query: 318 LTVRA-------LNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYA 370
V A + DA K + + L + G F S +++ +K G EV
Sbjct: 275 AIVDANRTRKDFIADAILSRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVII 334
Query: 371 YDPLCTREDAERFGAKWKED---FKDVDAIVIVTDHREFKTLDLKEIAAEVRTK 421
Y+P+ +ED+ F ++ + D FK ++I E +L ++A +V T+
Sbjct: 335 YEPV-MKEDS-FFNSRLERDLATFKQQADVIISNRMAE----ELSDVADKVYTR 382
>sp|Q07172|UDG_STRPY UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|1075776|pir||A46089 UDPglucose
6-dehydrogenase (EC 1.1.1.22) - Streptococcus pyogenes
>gi|8569328|pdb|1DLI|A Chain A, The First Structure Of
Udp-Glucose Dehydrogenase (Udpgdh) Reveals The Catalytic
Residues Necessary For The Two-Fold Oxidation
>gi|295189|gb|AAA26899.1| (L08444) UDP-glucose
hydrogenase [Streptococcus pyogenes]
Length = 402
Score = 80.4 bits (195), Expect = 4e-14
Identities = 99/404 (24%), Positives = 168/404 (41%), Gaps = 30/404 (7%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
IAV G G +GL L + + I VDI V+ +NNG + I++E L K +
Sbjct: 3 IAVAGSGYVGLSLGVLLSLQNEVTI-VDILPSKVDKINNGLSPIQDEYIEYYLKSKQLS- 60
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITEAT 142
+KAT D A K+A+++II PT + R N + K + +I ++T
Sbjct: 61 --IKATLDSKAAYKEAELVIIATPTNYNSRINYFDTQHVETVIKEVLSVNSHATLIIKST 118
Query: 143 MPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASDERT---- 198
+P G + + K + +PE A+ D YP + S E
Sbjct: 119 IPIG-------FITEMRQKFQTDRIIFSPEFLRESKALYD--NLYPSRIIVSCEENDSPK 169
Query: 199 ----LEAVIGIYETINRKGVIPMSSIKA--AEAVKVFEGIYRDVNIALANELALWCEEHG 252
E + ++ +K +P+ + A AEAVK+F Y + +A NEL + E
Sbjct: 170 VKADAEKFALLLKSAAKKNNVPVLIMGASEAEAVKLFANTYLALRVAYFNELDTYAESRK 229
Query: 253 LDAIEIFNAANTQPYCHLHM--PGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREINDS 310
L++ I + +H P G GG+C+P ++ LI N+
Sbjct: 230 LNSHMIIQGISYDDRIGMHYNNPSFGYGGYCLPKDTKQLLANYNNIPQTLIEAIVSSNNV 289
Query: 311 MPRHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYA 370
++ + + L + P+K + V L + F +S DVI LK ++
Sbjct: 290 RKSYIAKQIINVLKEQESPVK--VVGVYRLIMKSNSDNFRESAIKDVIDILKSKDIKIII 347
Query: 371 YDPLCTREDAERFGAKWK--EDFKDVDAIVIVTDHREFKTLDLK 412
Y+P+ + ++E E+FK A +IVT+ + + D+K
Sbjct: 348 YEPMLNKLESEDQSVLVNDLENFKK-QANIIVTNRYDNELQDVK 390
>sp|P37791|UDG_SHIFL UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|530776|emb|CAA50782.1| (X71970) frame shift
mutation between 15882 and 15885 [Shigella flexneri]
Length = 372
Score = 77.3 bits (187), Expect = 3e-13
Identities = 91/407 (22%), Positives = 173/407 (42%), Gaps = 51/407 (12%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
I + G G +GL + A N +V+ +DI V +N+ + P +D+ +++ +++
Sbjct: 3 ITISGTGYVGLSNGLLIAQNH-EVVALDILPSRVAMLND-----RISPIVDKEIQQFLQS 56
Query: 83 GRL--KATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITE 140
++ AT D A + AD +II PT D + N S + K + +++ +
Sbjct: 57 DKIHFNATLDKNEAYRDADYVIIATPTDYDPKTNYFNTSSVESVIKDVVEINPYAVMVIK 116
Query: 141 ATMPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASDERTLE 200
+T+P G T ++ K + +PE G A+ D ++G ER
Sbjct: 117 STVPVGFTAAMHK-------KYRTENIIFSPEFLREGKALYDNLHPSRIVIGERSERAER 169
Query: 201 AVIGIYETINRKGVIPM-SSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGLDAIEIF 259
+ E ++ + + + AEA+K+F Y + +A NEL + E GL+ +I
Sbjct: 170 FAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLNTRQII 229
Query: 260 NAANTQPYC--HLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREINDSMPRHVVE 317
P H + P G GG+C+P K +L+ + + +++
Sbjct: 230 EGVCLDPRIGNHYNNPSFGYGGYCLP-----------KDTKQLLANYQSVPNNL------ 272
Query: 318 LTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYAYDPLCTR 377
+ A+ DA + K V + + G F S +++ +K G EV Y+P+
Sbjct: 273 --ISAIVDANR-----KWWVFIVIMKSGSDNFRASSIQGIMKRIKAKGVEVIIYEPVMKG 325
Query: 378 EDAERFGAKWKED---FKDVDAIVIVTDHREFKTLDLKEIAAEVRTK 421
+ F ++ + D FK ++I E +LK++A +V T+
Sbjct: 326 DSF--FNSRLERDLATFKQQADVIISNRMAE----ELKDVADKVYTR 366
>pdb|1DLJ|A Chain A, The First Structure Of Udp-Glucose Dehydrogenase (Udpgdh)
Reveals The Catalytic Residues Necessary For The
Two-Fold Oxidation
Length = 402
Score = 76.5 bits (185), Expect = 6e-13
Identities = 98/404 (24%), Positives = 167/404 (41%), Gaps = 30/404 (7%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
IAV G G +GL L + + I VDI V+ +NNG + I++E L K +
Sbjct: 3 IAVAGSGYVGLSLGVLLSLQNEVTI-VDILPSKVDKINNGLSPIQDEYIEYYLKSKQLS- 60
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITEAT 142
+KAT D A K+A+++II PT + R N + K + +I ++T
Sbjct: 61 --IKATLDSKAAYKEAELVIIATPTNYNSRINYFDTQHVETVIKEVLSVNSHATLIIKST 118
Query: 143 MPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPKIVGASDERT---- 198
+P G + + K + +PE A+ D YP + S E
Sbjct: 119 IPIG-------FITEMRQKFQTDRIIFSPEFLRESKALYD--NLYPSRIIVSCEENDSPK 169
Query: 199 ----LEAVIGIYETINRKGVIPMSSIKA--AEAVKVFEGIYRDVNIALANELALWCEEHG 252
E + ++ +K +P+ + A AEAVK+F Y + +A NEL + E
Sbjct: 170 VKADAEKFALLLKSAAKKNNVPVLIMGASEAEAVKLFANTYLALRVAYFNELDTYAESRK 229
Query: 253 LDAIEIFNAANTQPYCHLHM--PGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREINDS 310
L++ I + +H P G GG+ +P ++ LI N+
Sbjct: 230 LNSHMIIQGISYDDRIGMHYNNPSFGYGGYSLPKDTKQLLANYNNIPQTLIEAIVSSNNV 289
Query: 311 MPRHVVELTVRALNDAGKPMKGSKILVLGLTFRGGVKEFTKSPAIDVIRELKEWGAEVYA 370
++ + + L + P+K + V L + F +S DVI LK ++
Sbjct: 290 RKSYIAKQIINVLKEQESPVK--VVGVYRLIMKSNSDNFRESAIKDVIDILKSKDIKIII 347
Query: 371 YDPLCTREDAERFGAKWK--EDFKDVDAIVIVTDHREFKTLDLK 412
Y+P+ + ++E E+FK A +IVT+ + + D+K
Sbjct: 348 YEPMLNKLESEDQSVLVNDLENFKK-QANIIVTNRYDNELQDVK 390
>gb|AAC43311.1| (U15171) UDP-glucose dehydrogenase [Streptococcus pneumoniae]
>gi|1095716|prf||2109359A UDP-glucose dehydrogenase
[Streptococcus pneumoniae]
Length = 394
Score = 73.4 bits (177), Expect = 5e-12
Identities = 95/414 (22%), Positives = 169/414 (39%), Gaps = 43/414 (10%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
IA+ G G +GL LA + A + +V +D+ + V S+NN ++ IK+E LV+K +
Sbjct: 3 IAIAGSGYVGLSLAVLLAQHH-EVKVIDVIKDKVESINNRKSPIKDEAIEKYLVEKELN- 60
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITEAT 142
L+A+ D K + II PT D N S + A K ++ ++T
Sbjct: 61 --LEASLDPAHVYKDVEYAIIATPTNYDVDLNQFDTSSVEAAIKTCMEYNDTCTIVIKST 118
Query: 143 MPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPK--IVGAS-DERTL 199
+P G T+ + K + +PE A+ D YP +VG D+ L
Sbjct: 119 IPEGYTKEVRE-------KFNTDRIIFSPEFLRESKALYD--NLYPSRIVVGTDLDDSEL 169
Query: 200 EAVIGIYETINRKGVIP------MSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGL 253
+ + + G I + + AE K+F Y +A NE+ + E GL
Sbjct: 170 TKRAWQFADLLKGGAIKEEVPILVVAFNEAEVAKLFSNTYLATRVAYFNEIDTYSEVKGL 229
Query: 254 DAIEIFNAANTQPY--CHLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREINDSM 311
+ I + P + P G GG+C+P K +L + R++ +++
Sbjct: 230 NPKTIIDIVCYDPRIGSDYNNPSFGYGGYCLP-----------KDTKQLKASFRDVPENL 278
Query: 312 PRHVVELTVRALNDAGKPMKGSKILVLG---LTFRGGVKEFTKSPAIDVIRELKEWGAEV 368
VV+ + + + V+G L + F S V+ L +G E+
Sbjct: 279 ITAVVQSNKTRKDYIAGAILAKQPSVVGIYRLIMKSDSDNFRSSAVKGVMERLDNYGKEI 338
Query: 369 YAYDPLCTREDAERFGA-KWKEDFKDVDAIVIVTDHREFKTLDLKEIAAEVRTK 421
Y+P + + K ++FK++ IV+ + DL++I ++ T+
Sbjct: 339 VIYEPTIECDTFMGYRVIKSLDEFKNISDIVVANRMND----DLRDIQEKLYTR 388
>sp|Q57346|UDG_STRPN UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH) >gi|1658317|emb|CAA87403.1| (Z47210) uridine
diphosphate glucose dehydrogenase [Streptococcus
pneumoniae]
Length = 394
Score = 72.6 bits (175), Expect = 9e-12
Identities = 94/414 (22%), Positives = 169/414 (40%), Gaps = 43/414 (10%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
IA+ G G +GL LA + A + +V +D+ + V S+NN ++ IK+E LV+K +
Sbjct: 3 IAIAGSGYVGLSLAVLLAQHH-EVKVIDVIKDKVESINNRKSPIKDEAIEKYLVEKEL-- 59
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITEAT 142
L+A+ D K + II PT D N S + A K ++ ++T
Sbjct: 60 -NLEASLDPAHVYKDVEYAIIATPTNYDVDLNQFDTSSVEAAIKTCMEYNDTCTIVIKST 118
Query: 143 MPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPK--IVGAS-DERTL 199
+P G T+ + K + +PE A+ D YP +VG D+ L
Sbjct: 119 IPEGYTKEVRE-------KFNTDRIIFSPEFLRESKALYD--NLYPSRIVVGTDLDDSEL 169
Query: 200 EAVIGIYETINRKGVIP------MSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGL 253
+ + + G I + + AE K+F Y + NE+ + E GL
Sbjct: 170 TKRAWQFADLLKGGAIKEEVPILVVAFNEAEVAKLFSNTYLATRVRYFNEIDTYSEVKGL 229
Query: 254 DAIEIFNAANTQPY--CHLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREINDSM 311
+ I + P + + P G GG+C+P K +L + R++ +++
Sbjct: 230 NPKTIIDIVCYDPRIGSYYNNPSFGYGGYCLP-----------KDTKQLKASFRDVPENL 278
Query: 312 PRHVVELTVRALNDAGKPMKGSKILVLG---LTFRGGVKEFTKSPAIDVIRELKEWGAEV 368
VV+ + + + V+G L + F S V+ L +G E+
Sbjct: 279 ITAVVQSNKTRKDYIAGAILAKQPSVVGIYRLIMKSDSDNFRSSAVKGVMERLDNYGKEI 338
Query: 369 YAYDPLCTREDAERFGA-KWKEDFKDVDAIVIVTDHREFKTLDLKEIAAEVRTK 421
Y+P + + K ++FK++ IV+ + DL++I ++ T+
Sbjct: 339 VIYEPTIECDTFMGYRVIKSLDEFKNISDIVVANRMND----DLRDIQEKLYTR 388
>emb|CAA78147.1| (Z12159) uridine diphosphate glucose dehydrogenase [Streptococcus
pneumoniae] >gi|1586508|prf||2204223D UDP-Glucose
dehydrogenase [Streptococcus pneumoniae]
Length = 394
Score = 69.5 bits (167), Expect = 7e-11
Identities = 93/414 (22%), Positives = 168/414 (40%), Gaps = 43/414 (10%)
Query: 23 IAVYGLGKMGLPLAAVFADNGAKVIGVDINERVVNSVNNGENHIKEEPGLDELVKKNVEA 82
IA+ G G +GL LA + A + +V +D+ + V S+NN ++ IK+E LV+K +
Sbjct: 3 IAIAGSGYVGLSLAVLLAQHH-EVKVIDVIKDKVESINNRKSPIKDEAIEKYLVEKEL-- 59
Query: 83 GRLKATTDGILAAKKADVMIILVPTLADDRGNLKLESVYDVAEKISKGLEKGDIVITEAT 142
L+A+ D K + II PT D N S + A K ++ ++T
Sbjct: 60 -NLEASLDPAHVYKDVEYAIIATPTNYDVDLNQFDTSSVEAAIKTCMEYNDTCTIVIKST 118
Query: 143 MPPGTTESLIPILEKSGLKLGDFGLAHAPERTMTGTAIRDITGQYPK--IVGAS-DERTL 199
+P G T+ + K + +PE A+ D YP +VG D+ L
Sbjct: 119 IPEGYTKEVRD-------KFNTDRIIFSPEFLRESKALYD--NLYPSRIVVGTDLDDSEL 169
Query: 200 EAVIGIYETINRKGVIP------MSSIKAAEAVKVFEGIYRDVNIALANELALWCEEHGL 253
+ + + G I + + AE K+F Y + NE+ + E L
Sbjct: 170 TKRAWQFADLLKGGAIKEEVPILVVAFNEAEVAKLFSNTYLATRVRYFNEIDTYSEVKEL 229
Query: 254 DAIEIFNAANTQPY--CHLHMPGAGVGGHCIPIYPWFVINLAKKTNVRLIRTAREINDSM 311
+ I + P + + P G GG+C+P K +L + R++ +++
Sbjct: 230 NPKTIIDIVCYDPRIGSYYNNPSFGYGGYCLP-----------KDTKQLKASFRDVPENL 278
Query: 312 PRHVVELTVRALNDAGKPMKGSKILVLG---LTFRGGVKEFTKSPAIDVIRELKEWGAEV 368
VV+ + + + V+G L + F S V+ L +G E+
Sbjct: 279 ITAVVQSNKTRKDYIAGAILAKQPSVVGIYRLIMKSDSDNFRSSAVKGVMERLDNYGKEI 338
Query: 369 YAYDPLCTREDAERFGA-KWKEDFKDVDAIVIVTDHREFKTLDLKEIAAEVRTK 421
Y+P + + K ++FK++ IV+ + DL++I ++ T+
Sbjct: 339 VIYEPTIECDTFMGYRVIKSLDEFKNISDIVVANRMND----DLRDIQEKLYTR 388
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.318 0.138 0.395
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 162042198
Number of Sequences: 2977
Number of extensions: 6919997
Number of successful extensions: 21031
Number of sequences better than 1.0e-10: 109
Number of HSP's better than 0.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 88
Number of HSP's that attempted gapping in prelim test: 20568
Number of HSP's gapped (non-prelim): 117
length of query: 448
length of database: 189,106,746
effective HSP length: 57
effective length of query: 391
effective length of database: 154,992,987
effective search space: 60602257917
effective search space used: 60602257917
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.6 bits)
S2: 166 (69.1 bits)