BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB0784 (graD-3) DE:glucose-1-phosphate thymidylyltransferase
(graD-3)
         (352 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||A75098 glucose-1-phosphate thymidylyltransferase (grad-3) P...   712  0.0
pir||F71151 probable glucose-1-phosphate thymidylyltransferase -...   668  0.0
pir||T48866 glucose-1-phosphate thymidylyltransferase (EC 2.7.7....   358  7e-98
pir||G72325 glucose-1-phosphate thymidylyltransferase - Thermoto...   355  4e-97
gb|AAD28517.1|AF126354_3 (AF126354) BlmD [Streptomyces bluensis]      350  1e-95
gi|11497938 glucose-1-phosphate thymidylyltransferase (graD-2) [...   347  8e-95
sp|P08075|STRD_STRGR GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (...   341  6e-93
pir||A26984 strD protein - Streptomyces griseus                       341  6e-93
pir||S76366 hypothetical protein - Synechocystis sp. (strain PCC...   335  4e-91
gb|AAF59934.1| (AF237895) dTDP-D-glucose synthase [Streptomyces ...   326  2e-88
pir||T51105 glucose-1-phosphate thymidylyltransferase (EC 2.7.7....   324  7e-88
pir||T30872 dNDP-glucose synthase - Streptomyces viridochromogen...   324  1e-87
emb|CAA07386.1| (AJ006985) StrD [Streptomyces glaucescens]            321  1e-86
gb|AAD13545.1| (AF080235) NDP-hexose synthetase homolog [Strepto...   310  1e-83
pir||T46521 probable dTDP-1-glucose synthase [imported] - Strept...   306  3e-82
gb|AAB50923.1| (L47163) glucose-1-phosphate thymidylyltransferas...   294  1e-78
gb|AAF00210.1|AF164960_6 (AF164960) dNDP-glucose synthetase [Str...   291  1e-77
pir||S58687 glucose-1-phosphate thymidylyltransferase (EC 2.7.7....   289  2e-77
pir||A75596 probable glucose-1-phosphate thymidylyltransferase -...   275  7e-73
emb|CAB57473.1| (Y18930) glucose-1-phosphate thymidylyltransfera...   270  1e-71
gb|AAK41126.1| Sugar phosphate nucleotydyl transferase [Sulfolob...   270  1e-71
gb|AAK41974.1| Sugar phosphate nucleotydyl transferase [Sulfolob...   263  2e-69
pir||A72589 probable glucose-1-phosphate thymidylyltransferase A...   238  6e-62
gb|AAD31893.2|AF144042_1 (AF144042) dTDP-glucose synthase [Strep...   211  1e-53
pir||D64437 glucose-1-phosphate thymidylyltransferase (EC 2.7.7....   206  2e-52
gb|AAG23610.1|AF244661_1 (AF244661) glucose-1-phosphate thymidyl...   203  2e-51
gb|AAG23575.1|AF244626_1 (AF244626) glucose-1-P thymidylyltransf...   199  3e-50
gb|AAD13560.1| (AF080235) NDP-hexose synthetase homolog [Strepto...   192  7e-48
pir||G75020 glucose-1-phosphate thymidylyltransferase (grad-2) P...   190  3e-47
pir||E71207 probable glucose-1-phosphate thymidylyltransferase -...   183  2e-45
gb|AAK41040.1| Sugar phosphate nucleotydyl transferase [Sulfolob...   178  6e-44
emb|CAB57558.1| (Y18930) glucose-1-phosphate thymidylyltransfera...   178  6e-44
pir||A69079 glucose-1-phosphate thymidylyltransferase homolog - ...   176  4e-43
sp|P39629|SPSI_BACSU SPORE COAT POLYSACCHARIDE BIOSYNTHESIS PROT...   159  4e-38
gb|AAG18651.1| (AE004970) glucose-1-phosphate thymidylyltransfer...   158  8e-38
gb|AAG19459.1| (AE005038) glucose-1-phosphate thymidylyltransfer...   155  9e-37
gb|AAG09515.1|AF279619_3 (AF279619) glucose-1-phosphate thymidyl...   152  5e-36
pir||G69101 mannose-1-phosphate guanyltransferase - Methanobacte...   152  6e-36
emb|CAB65204.1| (AJ007311) RmlA protein [Legionella pneumophila]      150  2e-35
gb|AAG09500.1|AF279615_3 (AF279615) glucose-1-phosphate thymidyl...   150  2e-35
dbj|BAB07082.1| (AP001518) spore coat polysaccharide synthesis (...   150  3e-35
gb|AAG09524.1|AF279621_3 (AF279621) glucose-1-phosphate thymidyl...   149  5e-35
sp|P55254|RFBA_SALAN GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (...   148  7e-35
gb|AAG09504.1|AF279616_3 (AF279616) glucose-1-phosphate thymidyl...   148  7e-35
pir||D55213 rfbA protein - Shigella flexneri (strain 2a) >gi|294...   148  9e-35
gb|AAG09532.1|AF279623_3 (AF279623) glucose-1-phosphate thymidyl...   148  1e-34
emb|CAC12604.1| (AL445067) mannose-1-phosphate guanyltransferase...   147  2e-34
sp|P26393|RFBA_SALTY GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (...   146  3e-34
sp|P37744|RBA1_ECOLI GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (...   146  3e-34
pir||I69650 glucose-1-phosphate thymidylyltransferase - Escheric...   146  3e-34
gb|AAG09536.1|AF279624_3 (AF279624) glucose-1-phosphate thymidyl...   146  3e-34
gb|AAD10181.1| (AF026471) Cps2L [Streptococcus pneumoniae]            146  5e-34
pir||D83000 glucose-1-phosphate thymidylyltransferase PA5163 [im...   146  5e-34
sp|P55253|RBA2_ECOLI GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (...   145  6e-34
sp|P95778|RMLA_STRMU GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (...   145  6e-34
gb|AAC35920.1| (AF071085) putative glucose-1-phosphate thymidyl ...   145  6e-34
gb|AAC38757.1| (AF030373) glucose-1-phosphate thymidyl transfera...   145  8e-34
gb|AAC44969.1| (U09239) glucose-1-phosphate thymidyl transferase...   145  1e-33
gb|AAC78674.1| (AF094575) glucose-1-phosphate thimidylyl transfe...   145  1e-33
gb|AAD19913.1| (AF105113) glucose-1-phosphate thymidylyl transfe...   145  1e-33
gb|AAG09519.1|AF279620_3 (AF279620) glucose-1-phosphate thymidyl...   145  1e-33
gb|AAG09539.1|AF279625_3 (AF279625) glucose-1-phosphate thymidyl...   145  1e-33
pir||S78498 probable glucose-1-phosphate thymidylyltransferase (...   144  1e-33
gb|AAG09528.1|AF279622_3 (AF279622) glucose-1-phosphate thymidyl...   144  1e-33
sp|P55256|RFBA_XANCA GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (...   144  2e-33
gb|AAD31799.1|AF128273_2 (AF128273) TDP-glucose synthase homolog...   144  2e-33
gb|AAG09508.1|AF279617_3 (AF279617) glucose-1-phosphate thymidyl...   144  2e-33
sp|P55255|RFBA_NEIMB GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (...   143  2e-33
gb|AAC37050.1| (L09189) glucose-1-phosphate thymidyl transferase...   143  3e-33
gb|AAG18702.1| (AE004975) glucose-1-phosphate thymidylyltransfer...   143  3e-33
gb|AAG09511.1|AF279618_3 (AF279618) glucose-1-phosphate thymidyl...   143  4e-33
gb|AAB47843.1| (U61226) RfbA [Leptospira interrogans] >gi|581432...   142  7e-33
gb|AAD12972.1| (AF078135) RmlA [Leptospira borgpetersenii]            142  7e-33
sp|P57040|RFBA_NEIMA GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (...   142  7e-33
pir||H75070 sugar-phosphate nucleotydyl transferase PAB0645 - Py...   141  9e-33
sp|P55464|RFBA_RHISN PROBABLE GLUCOSE-1-PHOSPHATE THYMIDYLYLTRAN...   141  1e-32
sp|P27831|RFFH_ECOLI GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (...   141  2e-32
gb|AAD40709.1|AF048749_5 (AF048749) glucose-1-phosphate thymidyl...   139  3e-32
gb|AAF01820.1|AF187532_16 (AF187532) putative dTDP-glucose synth...   139  3e-32
emb|CAA80332.1| (Z22611) OAC3 [Azorhizobium caulinodans]              139  4e-32
pir||C36864 probable glucose-1-phosphate thymidylyltransferase -...   139  4e-32
pir||A71095 probable sugar-phosphate nucleotydyl transferase - P...   139  4e-32
pir||B75008 glucose-1-phosphate thymidylyltransferase (grad-1) P...   139  4e-32
gb|AAD56730.1|AF125164_3 (AF125164) glucose-1-phosphate thymidyl...   138  8e-32
pir||A70363 mannose-1-phosphate guanyltransferase - Aquifex aeol...   138  1e-31
sp|P37779|RFBA_SHIFL GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (...   138  1e-31
emb|CAC01394.1| (AJ131360) glucose-1-phosphate thymidyltransfera...   138  1e-31
gb|AAC68682.1| (AF079762) alpha-D-glucose-1-phosphate thymidylyl...   136  3e-31
gb|AAG18650.1| (AE004970) glucose-1-phosphate thymidylyltransfer...   136  4e-31
gb|AAC70774.1| (AF097519) glucose-1-phosphate thymidylyl transfe...   136  5e-31
gb|AAD28705.2|AF101047_6 (AF101047) putative glucose-1-phosphate...   135  7e-31
emb|CAC12985.1| (AJ250327) glucose-1-phosphate thymidyltransfera...   135  7e-31
gb|AAD01737.1| (AF022716) GDP-mannose pyrophosphorylase [Solanum...   134  2e-30
gb|AAF73461.1|AF264025_12 (AF264025) putative dTDP-1-glucose syn...   134  2e-30
gb|AAD05455.1| (AF064070) putative glucose-1-phosphate thymidylt...   134  2e-30
pir||T47698 mannose-1-phosphate guanylyltransferase-like protein...   134  2e-30
sp|P37762|RFBA_NEIGO GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (...   133  3e-30
emb|CAB05930.1| (Z83335) glucose-1-phosphate thymidylyltransfera...   133  3e-30
pir||T01007 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13...   133  3e-30
gb|AAA67589.1| (M87049) similar to Streptomyces griseus StrD pro...   132  4e-30
gb|AAC44072.1| (U51197) glucose-1-phosphate thymidylyltransferas...   132  6e-30
pir||T00103 glucose-1-phosphate thymidylyltransferase (EC 2.7.7....   132  6e-30
dbj|BAA82533.1| (AB030032) glucose-1-phosphate thymidylyltransfe...   132  6e-30
emb|CAB79775.1| (AL161577) GDP-mannose pyrophosphorylase like pr...   132  6e-30
gb|AAK40653.1| Sugar phosphate nucleotydyl transferase [Sulfolob...   132  8e-30
emb|CAB01949.1| (Z79692) ExpA7 [Sinorhizobium meliloti]               132  8e-30
dbj|BAA94403.1| (AB041266) D-glucose-1-phosphate thymidylyltrans...   132  8e-30
dbj|BAA19634.1| (AB002668) glucose-1-phosphate-thymidylyltransfe...   131  1e-29
pir||D75597 glucose-1-phosphate thymidylyltransferase - Deinococ...   131  2e-29
emb|CAB88884.1| (AL353861) putative mannose-1-phosphate guanyltr...   131  2e-29
pir||S30683 hypothetical protein o292 - Escherichia coli              130  3e-29
pir||C69106 glucose-1-phosphate thymidylyltransferase (EC 2.7.7....   130  3e-29
dbj|BAA84594.1| (AB032523) glucose-1-phosphate thymidyltransfera...   129  5e-29
gb|AAF52089.1| (AE003605) CG1129 gene product [alt 1] [Drosophil...   127  2e-28
pir||B71146 probable glucose-1 phosphate transferase - Pyrococcu...   127  2e-28
pir||G70527 glucose-1-phosphate thymidylyltransferase (EC 2.7.7....   127  2e-28
pir||T41209 mannose-1-phosphate guanyltransferase - fission yeas...   126  3e-28
pir||T32900 hypothetical protein C42C1.5 - Caenorhabditis elegan...   125  6e-28
pir||G75164 mannose-1-phosphate guanyltransferase PAB0317 - Pyro...   125  1e-27
gb|AAA69677.1| (U24437) mannose-1-phosphate guanyltransferase [S...   123  2e-27
gi|6320148 mannose-1-phosphate guanyltransferase, GDP-mannose py...   122  5e-27
pir||T42371 probable mannose-1-phosphate guanylyltransferase (EC...   122  6e-27
dbj|BAA77382.1| (AB020570) GDP-mannose pyrophosphorylase [Candid...   122  8e-27
pir||C71177 probable mannose-1-phosphate guanyltransferase - Pyr...   121  1e-26
emb|CAA77210.1| (Y18523) dTDP-glucose synthase [Actinoplanes sp....   121  1e-26
sp|P55257|RFBA_YEREN GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (...   120  3e-26
gb|AAF67515.1|AF170880_22 (AF170880) NovV [Streptomyces spheroides]   120  3e-26
gb|AAG29804.1| (AF235050) dTDP-glucose synthase; glucose-1-phosp...   119  4e-26
pir||S49053 glucose-1-phosphate thymidylyltransferase (EC 2.7.7....   117  2e-25
gb|AAD23920.1|AF083467_4 (AF083467) glucose-1-phosphate thymidyl...   117  2e-25
gb|AAD45556.1|U70376_21 (U70376) SpcK [Streptomyces flavopersicus]    116  3e-25
pir||H82325 UTP--glucose-1-phosphate uridylyltransferase VC0395 ...   116  3e-25
gi|11431484 GDP-mannose pyrophosphorylase B [Homo sapiens]            116  4e-25
pir||A83394 UTP--glucose-1-phosphate uridylyltransferase PA2023 ...   116  5e-25
emb|CAB58292.1| (AL121851) mannose-1-phosphate guanyltransferase...   115  6e-25
gb|AAD31796.1|AF128272_1 (AF128272) TDP-glucose synthase [Strept...   115  6e-25
gi|7019397 GDP-mannose pyrophosphorylase B [Homo sapiens] >gi|50...   115  6e-25
dbj|BAB14882.1| (AK024319) unnamed protein product [Homo sapiens]     115  1e-24
gb|AAC64911.1| (AF030299) putative GDP-mannose pyrophosphorylase...   113  3e-24
dbj|BAA34807.1| (AB020596) GDP-mannose pyrophosphorylase [Candid...   113  4e-24
gb|AAC39498.1| (U89991) mannose-1-phosphate guanylyltransferase ...   113  4e-24
gb|AAC64912.1| (AF030300) putative GDP-mannose pyrophosphorylase...   113  4e-24
pir||A75096 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7...   113  4e-24
gb|AAF60300.1|AF234177_1 (AF234177) GDP-mannose pyrophosphorylas...   111  1e-23
gi|11497858 glucose-1-phosphate thymidylyltransferase (graD-1) [...   110  2e-23
pir||A70978 probable rmlA2 protein - Mycobacterium tuberculosis ...   109  6e-23
pir||S76785 hypothetical protein - Synechocystis sp. (strain PCC...   106  4e-22
pir||C70354 UDP-N-acetylglucosamine pyrophosphorylase - Aquifex ...   105  7e-22
gb|AAK40709.1| Sugar phosphate nucleotydyl transferase [Sulfolob...   102  8e-21
pir||A72403 glucose-1-phosphate adenylyltransferase - Thermotoga...   100  4e-20
gb|AAD19415.1| (AF102543) UTP-glucose-1-phosphate uridyltransfer...    97  4e-19
pir||F72591 probable sugar phosphate transferase APE1202 - Aerop...    92  9e-18
gb|AAK41261.1| Sugar phosphate nucleotydyl transferase [Sulfolob...    92  1e-17
sp|P39122|GLGC_BACSU GLUCOSE-1-PHOSPHATE ADENYLYLTRANSFERASE (AD...    91  2e-17
pir||D72592 probable glucose-1-phosphate thymidylyltransferase A...    89  1e-16
gb|AAF81069.1|AF223364_4 (AF223364) mannose-1-phosphate-guanyltr...    85  1e-15
emb|CAB88923.1| (AL353862) putative nucleotide phosphorylase [St...    83  5e-15
pir||B72403 glucose-1-phosphate adenylyltransferase - Thermotoga...    82  8e-15
pir||S75920 hypothetical protein - Synechocystis sp. (strain PCC...    82  1e-14
dbj|BAB07043.1| (AP001518) glucose-1-phosphate thymidylyltransfe...    82  1e-14
gb|AAG18947.1| (AE004996) glucose-1-phosphate thymidylyltransfer...    81  2e-14
dbj|BAB04806.1| (AP001510) glucose-1-phosphate adenylyltransfera...    76  4e-13
pir||E72229 UDP-N-acetylglucosamine pyrophosphorylase - Thermoto...    76  4e-13
pir||S66080 UDP-N-acetylglucosamine pyrophosphorylase gcaD - Bac...    75  2e-12
sp|P14192|GCAD_BACSU UDP-N-ACETYLGLUCOSAMINE PYROPHOSPHORYLASE (...    72  1e-11
dbj|BAB03784.1| (AP001507) UDP-N-acetylglucosamine pyrophosphory...    69  6e-11

>pir||A75098 glucose-1-phosphate thymidylyltransferase (grad-3) PAB0784 -
           Pyrococcus abyssi (strain Orsay)
           >gi|5458598|emb|CAB50086.1| (AJ248286)
           glucose-1-phosphate thymidylyltransferase (graD-3)
           [Pyrococcus abyssi]
           Length = 352
           
 Score =  712 bits (1818), Expect = 0.0
 Identities = 352/352 (100%), Positives = 352/352 (100%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV
Sbjct: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60

Query: 61  IETVKSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKEHF 120
           IETVKSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKEHF
Sbjct: 61  IETVKSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKEHF 120

Query: 121 EKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPIIHE 180
           EKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPIIHE
Sbjct: 121 EKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPIIHE 180

Query: 181 AVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLDEIER 240
           AVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLDEIER
Sbjct: 181 AVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLDEIER 240

Query: 241 EIKVETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSVGNNVVIEDT 300
           EIKVETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSVGNNVVIEDT
Sbjct: 241 EIKVETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSVGNNVVIEDT 300

Query: 301 EVEDSIIMDGSVIIGAGRIIESIIGKEVRIVRGDGHPLGRRLIVGDKSQLTL 352
           EVEDSIIMDGSVIIGAGRIIESIIGKEVRIVRGDGHPLGRRLIVGDKSQLTL
Sbjct: 301 EVEDSIIMDGSVIIGAGRIIESIIGKEVRIVRGDGHPLGRRLIVGDKSQLTL 352


>pir||F71151 probable glucose-1-phosphate thymidylyltransferase - Pyrococcus
           horikoshii >gi|3256816|dbj|BAA29499.1| (AP000002) 356aa
           long hypothetical glucose-1-phosphate
           thymidylyltransferase [Pyrococcus horikoshii]
           Length = 356
           
 Score =  668 bits (1704), Expect = 0.0
 Identities = 319/352 (90%), Positives = 343/352 (96%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGI+VGPN + V
Sbjct: 5   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIVVGPNADLV 64

Query: 61  IETVKSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKEHF 120
            +TV SVDWDANIEFIYQGEPKGLAHAILVARDYLG++DFVMYLGDNILREGIVRHKEHF
Sbjct: 65  KKTVMSVDWDANIEFIYQGEPKGLAHAILVARDYLGDEDFVMYLGDNILREGIVRHKEHF 124

Query: 121 EKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPIIHE 180
           EKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRL+EKPKHPPSNLALVGIYFFRPIIHE
Sbjct: 125 EKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLVEKPKHPPSNLALVGIYFFRPIIHE 184

Query: 181 AVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLDEIER 240
           AVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLDEIE+
Sbjct: 185 AVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLDEIEK 244

Query: 241 EIKVETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSVGNNVVIEDT 300
           E+KVETRAKIIGRVKIEEGA+IDEN++IKGPAVIG+NAVIRNAYIGPYTSVGNNVVIEDT
Sbjct: 245 EVKVETRAKIIGRVKIEEGAQIDENSVIKGPAVIGKNAVIRNAYIGPYTSVGNNVVIEDT 304

Query: 301 EVEDSIIMDGSVIIGAGRIIESIIGKEVRIVRGDGHPLGRRLIVGDKSQLTL 352
           EVEDSI+MD S+I+GAGRI+ESIIG+ V+I++G+ HP+GRRLI+GD SQ+ L
Sbjct: 305 EVEDSIVMDDSIIVGAGRIVESIIGRGVKIIKGNSHPMGRRLIIGDNSQIVL 356


>pir||T48866 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) [validated]
           - Streptomyces argillaceus >gi|1814004|emb|CAA71846.1|
           (Y10907) TDP-D-Glucose synthase [Streptomyces
           argillaceus] >gi|3334819|emb|CAA07754.1| (AJ007932)
           dTDP-glucose synthase [Streptomyces argillaceus]
           Length = 355
           
 Score =  358 bits (908), Expect = 7e-98
 Identities = 180/352 (51%), Positives = 245/352 (69%), Gaps = 5/352 (1%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MKAL+LSGG GTRLRP+T++  KQL+PVANKPVLFYA+ED+ +AGI ++GI+VG    ++
Sbjct: 1   MKALVLSGGSGTRLRPITHTSPKQLVPVANKPVLFYALEDIAQAGITDVGIVVGETAREI 60

Query: 61  IETV-KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKEH 119
            + V     +   + ++ Q +P GLAHA+L+ARDYLG+DDFVMYLGDN +  GI    + 
Sbjct: 61  EDAVGDGSKFGLQVTYLPQEKPLGLAHAVLIARDYLGDDDFVMYLGDNFVVGGIAGLVDE 120

Query: 120 FEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPIIH 179
           F     DA ILL  VP+P  FG+AEL  +G+ + RL EKP HP S++A++G+Y F P++H
Sbjct: 121 FRADRPDARILLTPVPDPTAFGIAELDGEGRVV-RLEEKPTHPKSDMAVIGVYLFTPLVH 179

Query: 180 EAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLDEIE 239
           EAVR I+PSWR ELEIT AIQWLIDN + V  T + G+WKDTG   D+LE NR VL+ +E
Sbjct: 180 EAVRAIEPSWRGELEITHAIQWLIDNRHDVRSTVIHGYWKDTGNVMDMLEVNRTVLEGVE 239

Query: 240 --REIKVETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSVGNNVVI 297
              E  V+  +++IGRV+IE GA++  + I+ GPAVIG   VI  +YIGPYTSV     I
Sbjct: 240 PCTEGPVDAESEVIGRVRIEAGARVSNSRIV-GPAVIGSGTVISGSYIGPYTSVSEGCRI 298

Query: 298 EDTEVEDSIIMDGSVIIGAGRIIESIIGKEVRIVRGDGHPLGRRLIVGDKSQ 349
           ED+E+E SI++  S + G  R+  S+IG+ V +      P G RL++GD S+
Sbjct: 299 EDSEIEFSIVLRDSRVRGVQRVRGSLIGRSVTVAPAPRKPAGTRLVLGDHSE 350


>pir||G72325 glucose-1-phosphate thymidylyltransferase - Thermotoga maritima
           (strain MSB8) >gi|4981396|gb|AAD35944.1|AE001752_11
           (AE001752) glucose-1-phosphate thymidylyltransferase
           [Thermotoga maritima]
           Length = 355
           
 Score =  355 bits (902), Expect = 4e-97
 Identities = 179/356 (50%), Positives = 255/356 (71%), Gaps = 8/356 (2%)

Query: 2   KALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQVI 61
           KA++L  G GTRLRPLT++  K LIP+ANKP+LFY++E++  AGI E+GI+V P+  +  
Sbjct: 3   KAIVLCAGKGTRLRPLTFTTAKHLIPIANKPILFYSLENIARAGIEEVGIVVSPHNAEEF 62

Query: 62  ETVKSV--DWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKEH 119
           +++     ++   I +I Q EPKGLAHA+ V+R++LG++DF+MYLGDN++ E + +  + 
Sbjct: 63  KSIVGTGENFGLRISYIIQEEPKGLAHAVWVSREFLGDEDFMMYLGDNLILEDLGKFVKD 122

Query: 120 FEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPIIH 179
           FE SDY ASILL  V +P +FGVA +  +G  + +++EKPK PPSNLA+VG+Y FR  I 
Sbjct: 123 FENSDYAASILLSPVKDPTRFGVAVM--EGDRVIKVVEKPKTPPSNLAIVGLYLFRNKIF 180

Query: 180 EAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLDEIE 239
           E +++IKPSWR ELEITDAI++LI+ G KV    V GWWKDTGKPEDLLEANR +L E  
Sbjct: 181 EGIKNIKPSWRGELEITDAIEYLIEKGEKVRGYIVYGWWKDTGKPEDLLEANRKILMETT 240

Query: 240 REI--KVETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSVGNNVVI 297
            E+  +++ ++ I G V+I + +KI  N++I+GPAVIG N  I+N+Y+GPY+S+GN V++
Sbjct: 241 EELLGEMDDKSSIQGPVRIGKASKI-VNSVIRGPAVIGENCFIKNSYVGPYSSIGNRVIL 299

Query: 298 EDTEVEDSIIMDGSVIIGA-GRIIESIIGKEVRIVRGDGHPLGRRLIVGDKSQLTL 352
           ED EVE+SI+MD   I G   RI  SI+GK V +      P    LI+G+ S++ L
Sbjct: 300 EDCEVENSIVMDECSITGVEKRIDSSILGKGVSVKGSQKRPASLNLILGNMSRVEL 355


>gb|AAD28517.1|AF126354_3 (AF126354) BlmD [Streptomyces bluensis]
           Length = 355
           
 Score =  350 bits (889), Expect = 1e-95
 Identities = 176/351 (50%), Positives = 242/351 (68%), Gaps = 5/351 (1%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MKAL+L+GG GTRLRP+T++  KQL+PVANKPVLFY +E +  AGI  +G+IVG     +
Sbjct: 1   MKALVLAGGSGTRLRPITHTSAKQLVPVANKPVLFYGLEAIAAAGIKNVGLIVGDMSGDI 60

Query: 61  IETV-KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKEH 119
            E V     +  +I +I Q EP GLAHA+L++RDYLG DDF MYLGDN +  GI      
Sbjct: 61  SEAVGDGSKFGLSISYIEQREPLGLAHAVLISRDYLGEDDFAMYLGDNFIVGGIDEPVRE 120

Query: 120 FEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPIIH 179
           F +   DA +LL  V +PQ FGVAEL   G+ ++ L EKP+HP S+LALVG+Y F P IH
Sbjct: 121 FRRDRPDAHLLLTHVSDPQSFGVAELDATGR-VRGLEEKPRHPKSDLALVGVYLFSPAIH 179

Query: 180 EAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLDEIE 239
           EAVR +KPSWR ELEITDA+QWLID G  V   ++TG+WKDTG   D+LE NRLVL+ I+
Sbjct: 180 EAVRAVKPSWRGELEITDAVQWLIDTGKDVRSRQITGYWKDTGNVSDMLEVNRLVLETID 239

Query: 240 REI--KVETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSVGNNVVI 297
                 V+  + ++GRV++++GA +  N+ + GPAVIG  +V+ ++Y+GP+TS+G + VI
Sbjct: 240 PHCAGHVDEHSDLVGRVQVDDGAVV-RNSRVVGPAVIGAGSVVVDSYVGPFTSIGEDCVI 298

Query: 298 EDTEVEDSIIMDGSVIIGAGRIIESIIGKEVRIVRGDGHPLGRRLIVGDKS 348
           ED+EVE SI++  + + G  R+  S+IG+ V++      P   RL++GD S
Sbjct: 299 EDSEVEFSIVLRRASLSGVRRVEASLIGRHVQVTSAPPVPHAHRLVLGDHS 349


>gi|11497938 glucose-1-phosphate thymidylyltransferase (graD-2) [Archaeoglobus
           fulgidus] >gi|7448159|pir||E69290 glucose-1-phosphate
           thymidylyltransferase (graD-2) homolog - Archaeoglobus
           fulgidus >gi|2650311|gb|AAB90910.1| (AE001082)
           glucose-1-phosphate thymidylyltransferase (graD-2)
           [Archaeoglobus fulgidus]
           Length = 352
           
 Score =  347 bits (882), Expect = 8e-95
 Identities = 173/356 (48%), Positives = 256/356 (71%), Gaps = 8/356 (2%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK ++L GG GTRLRPLT++  KQLIPVANKPV  Y +ED+I AGI E+ II+G    ++
Sbjct: 1   MKGVLLHGGAGTRLRPLTFTGPKQLIPVANKPVSQYCLEDMIGAGIKEVAIILGETYPEM 60

Query: 61  IETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKE 118
           +E        +   I +I+QG+P G+AHA+ +A+D++G++ FV+YLGDN++++GI  + +
Sbjct: 61  VEEHYGDGSRFGCKITYIHQGKPLGIAHAVYLAKDFVGDEKFVVYLGDNLIQDGIKEYVK 120

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPII 178
            F++ D+DA ILL EV +P+ FGVA+   +G+ +  LIEKPK PPSN A++G+Y F+P++
Sbjct: 121 RFDEEDFDAFILLKEVEDPRAFGVAKF--EGERLVGLIEKPKEPPSNYAVIGVYMFKPVV 178

Query: 179 HEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLDE- 237
            + ++ +KPSWR ELEITD +Q +I+NGY VG+ K+ GWW DTGK ED+L+ N  +LDE 
Sbjct: 179 FDIIKDLKPSWRGELEITDTLQKMIENGYNVGYAKLKGWWFDTGKAEDILKVNATILDER 238

Query: 238 IEREIKVETRA-KIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSVGNNVV 296
            +R +K E  A +I GRV++ EGAKI  N+I++GPAVIG + +I N++IGPYTSVG   V
Sbjct: 239 AKRSVKGEVLASQIEGRVEVGEGAKI-TNSIVRGPAVIGEDCIIENSFIGPYTSVGERTV 297

Query: 297 IEDTEVEDSIIMDGSVIIGAGRIIESIIGKEVRIVRGDGHPLGRRLIVGDKSQLTL 352
           I+++ +E  I++  S+I G  RI ES+IG++VRI + D      R  +GD S++ L
Sbjct: 298 IKNSSLEYCIVLSESIIEGVERIEESLIGRKVRIRKNDRKRF-LRFTIGDYSEILL 352


>sp|P08075|STRD_STRGR GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (DTDP-GLUCOSE SYNTHASE)
           (DTDP-GLUCOSE PYROPHOSPHORYLASE) (SUGAR-NUCLEOTIDYLATION
           ENZYME) >gi|49261|emb|CAA68514.1| (Y00459) put.
           sugaractivating enzyme [Streptomyces griseus]
           Length = 355
           
 Score =  341 bits (866), Expect = 6e-93
 Identities = 172/352 (48%), Positives = 239/352 (67%), Gaps = 5/352 (1%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MKAL+L+GG GTRLRP+T++  KQL+PVANKPVLFY +E +  AGI ++GI+VG   +++
Sbjct: 1   MKALVLAGGTGTRLRPITHTSAKQLVPVANKPVLFYGLEAIRAAGIIDVGIVVGDTADEI 60

Query: 61  IETVKSVD-WDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKEH 119
           +  V     +   + +I Q +P GLAH +L++RD+LG DDF+MYLGDN +   +      
Sbjct: 61  VAAVGDGSRFGLKVSYIPQSKPLGLAHCVLISRDFLGEDDFIMYLGDNFVVGVVEDSVRE 120

Query: 120 FEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPIIH 179
           F  +  DA ++L  VP P+ FGVAELS+ G+ +  L EKP HP S+LALVG+Y F P IH
Sbjct: 121 FRAARPDAHLMLTRVPEPRSFGVAELSDSGQVLG-LEEKPAHPKSDLALVGVYLFSPAIH 179

Query: 180 EAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLDEIE 239
           EAV  I PSWR ELEITDA+QWLID G  V  T ++G+WKDTG   D+LE NRLVL+  E
Sbjct: 180 EAVAAITPSWRGELEITDAVQWLIDAGRDVRSTVISGYWKDTGNVTDMLEVNRLVLETTE 239

Query: 240 REIK--VETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSVGNNVVI 297
                 V+ R+ +IGRV +EEGA++  N+ + GP VIG    + N+Y+GP+TS+  + V+
Sbjct: 240 PRCDGLVDERSDLIGRVLVEEGAEV-RNSRVMGPTVIGAGTRVTNSYVGPFTSLAEDCVV 298

Query: 298 EDTEVEDSIIMDGSVIIGAGRIIESIIGKEVRIVRGDGHPLGRRLIVGDKSQ 349
           ED+EVE SI++ G+ I G  RI  S+IG+ V++      P   RL++GD S+
Sbjct: 299 EDSEVEFSIVLRGASISGVRRIEASLIGRHVQVTSAPEVPHANRLVLGDHSR 350


>pir||A26984 strD protein - Streptomyces griseus
           Length = 355
           
 Score =  341 bits (866), Expect = 6e-93
 Identities = 172/352 (48%), Positives = 239/352 (67%), Gaps = 5/352 (1%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MKAL+L+GG GTRLRP+T++  KQL+PVANKPVLFY +E +  AGI ++GI+VG   +++
Sbjct: 1   MKALVLAGGTGTRLRPITHTSAKQLVPVANKPVLFYGLEAIRAAGIIDVGIVVGDTADEI 60

Query: 61  IETVKSVD-WDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKEH 119
           +  V     +   + +I Q +P GLAH +L++RD+LG DDF+MYLGDN +   +      
Sbjct: 61  VAAVGDGSRFGLKVSYIPQSKPLGLAHCVLISRDFLGEDDFIMYLGDNFVVGVVEDSVRE 120

Query: 120 FEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPIIH 179
           F  +  DA ++L  VP P+ FGVAELS+ G+ +  L EKP HP S+LALVG+Y F P IH
Sbjct: 121 FRAARPDAHLMLTRVPEPRSFGVAELSDSGQVLG-LEEKPAHPKSDLALVGVYLFSPAIH 179

Query: 180 EAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLDEIE 239
           EAV  I PSWR ELEITDA+QWLID G  V  T ++G+WKDTG   D+LE NRLVL+  E
Sbjct: 180 EAVAAITPSWRGELEITDAVQWLIDAGRDVRSTVISGYWKDTGNVTDMLEVNRLVLETTE 239

Query: 240 REIK--VETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSVGNNVVI 297
                 V+ R+ +IGRV +EEGA++  N+ + GP VIG    + N+Y+GP+TS+  + V+
Sbjct: 240 PRCDGLVDERSDLIGRVLVEEGAEV-RNSRVMGPTVIGAGTRVTNSYVGPFTSLAEDCVV 298

Query: 298 EDTEVEDSIIMDGSVIIGAGRIIESIIGKEVRIVRGDGHPLGRRLIVGDKSQ 349
           ED+EVE SI++ G+ I G  RI  S+IG+ V++      P   RL++GD S+
Sbjct: 299 EDSEVEFSIVLRGASISGVRRIEASLIGRHVQVTSAPEVPHAHRLVLGDHSR 350


>pir||S76366 hypothetical protein - Synechocystis sp. (strain PCC 6803)
           >gi|1001590|dbj|BAA10218.1| (D64000) glucose-1-phosphate
           thymidylyltransferase [Synechocystis sp.]
           Length = 393
           
 Score =  335 bits (851), Expect = 4e-91
 Identities = 172/358 (48%), Positives = 246/358 (68%), Gaps = 8/358 (2%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MKALILSGG GTRLRPLTY+  KQL+PVANKP+L+Y IE + +AGI +IGII+ P   + 
Sbjct: 29  MKALILSGGKGTRLRPLTYTGAKQLVPVANKPILWYGIEAIAKAGITDIGIIISPETGEE 88

Query: 61  IETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKE 118
           I+T+      +   I +I Q EP GLAHA+  A D+L +  FVMYLGDN++++ + +   
Sbjct: 89  IKTITGNGEKFGIQITYILQSEPLGLAHAVKTAADFLQDSPFVMYLGDNLIQDHLEQFLA 148

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPII 178
           HF+    D+ ILL  V NP  FGVA +++ GK +  L+EKP+HPPSNLALVG+YFF P I
Sbjct: 149 HFQAKSLDSLILLRRVSNPSAFGVATVNDQGKVLA-LVEKPEHPPSNLALVGLYFFAPTI 207

Query: 179 HEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLDE- 237
           H+A+ +I+PS R ELEITDAIQ+LI + Y+V   ++ GWW DTGK +DLL AN+++LD  
Sbjct: 208 HQAIANIEPSARGELEITDAIQYLISHDYRVESLQLKGWWLDTGKKDDLLAANQIILDTL 267

Query: 238 IEREIK--VETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSVGNNV 295
           +E+ I+  V+ ++KI GRV I   ++I  N++I+GP  IG N  + N +IGPY+S+   V
Sbjct: 268 VEKNIQGTVDDQSKISGRVTIGPHSQI-INSVIRGPVAIGPNCHLENCFIGPYSSIAEGV 326

Query: 296 VIEDTEVEDSIIMDGSVIIG-AGRIIESIIGKEVRIVRGDGHPLGRRLIVGDKSQLTL 352
            I D ++E S+++ G+ I+    RI++S+IGK  +I      P   R ++G+ SQ+ L
Sbjct: 327 KIRDADLEHSVVLQGASIVAIQQRIVDSVIGKNAKIFPAPRRPQALRFLIGNDSQVEL 384


>gb|AAF59934.1| (AF237895) dTDP-D-glucose synthase [Streptomyces antibioticus]
           Length = 356
           
 Score =  326 bits (827), Expect = 2e-88
 Identities = 177/356 (49%), Positives = 238/356 (66%), Gaps = 6/356 (1%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MKAL+L+GG GTRLRP+T++  KQL+ VANKPVLFY +E +  AGI ++G+IVG    +V
Sbjct: 1   MKALVLAGGSGTRLRPITHTSAKQLVAVANKPVLFYGLEAIAAAGITDVGLIVGDTAGEV 60

Query: 61  IETV-KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKEH 119
              V     +  +I +I Q  P GLAHA+L+A  YLG+DDFVMYLGDN +  GI      
Sbjct: 61  RAAVGDGAKFGLDITYIEQSRPLGLAHAVLIAHTYLGDDDFVMYLGDNFIVGGIDDLVRT 120

Query: 120 FEKSDYDAS-ILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPII 178
           F      A+ ILL  V +P  FGVAEL +DG+ +  L EKP+HP S+LALVG+YFF P I
Sbjct: 121 FRDGRPPAARILLTHVSDPSAFGVAELDDDGRVVG-LEEKPRHPKSDLALVGVYFFTPAI 179

Query: 179 HEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLDEI 238
           HEAVR I+PSWR ELEIT AIQ LIDNG  +    + G+WKDTG   D+LE NR VL+++
Sbjct: 180 HEAVRAIEPSWRGELEITHAIQHLIDNGADIQSMVIEGYWKDTGNVADMLEVNRTVLEDL 239

Query: 239 EREIK--VETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSVGNNVV 296
           E  I+  V+    +IGRV + EGA++  N+ I GPA+IG  A I ++YIGP+TSVG+N  
Sbjct: 240 EPRIEGTVDEHTVVIGRVVVGEGARV-TNSRIMGPAIIGAGAEISDSYIGPFTSVGDNCR 298

Query: 297 IEDTEVEDSIIMDGSVIIGAGRIIESIIGKEVRIVRGDGHPLGRRLIVGDKSQLTL 352
           I  +E+E SI++  S I G  RI  S+IG+ V++ +    P   R ++GD S++ +
Sbjct: 299 ITGSEMEFSIMLAESAITGVRRIEGSLIGRNVQVTQSLHAPNAHRFVLGDHSKVEI 354


>pir||T51105 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) [validated]
           - Streptomyces antibioticus (ATCC 11891)
           >gi|5902169|gb|AAD55453.1| (AF055579) dTDP-D-glucose
           synthase [Streptomyces antibioticus]
           Length = 356
           
 Score =  324 bits (823), Expect = 7e-88
 Identities = 176/356 (49%), Positives = 237/356 (66%), Gaps = 6/356 (1%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MKAL+L+GG GTRLRP+T++  KQL+ VANKPVLFY +E +  AGI ++G+IVG    +V
Sbjct: 1   MKALVLAGGSGTRLRPITHTSAKQLVAVANKPVLFYGLEAIAAAGITDVGLIVGDTAGEV 60

Query: 61  IETV-KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKEH 119
              V     +  +I +I Q  P GLAHA+L+A  YLG+DDFVMYLGDN +  GI      
Sbjct: 61  PRAVGDGAKFGLDITYIEQSRPLGLAHAVLIAHTYLGDDDFVMYLGDNFIVGGIDDLVRT 120

Query: 120 FEKSDYDAS-ILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPII 178
           F      A+ ILL  V +P  FGVAEL +DG+ +  L EKP+HP S+LALVG+YFF P I
Sbjct: 121 FRDGRRPAARILLTHVSDPSGFGVAELDDDGRVVG-LEEKPRHPKSDLALVGVYFFTPAI 179

Query: 179 HEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLDEI 238
           HEAVR I+PSWR ELEIT AIQ LIDNG  +    + G+WKDTG   D+LE NR VL+++
Sbjct: 180 HEAVRAIEPSWRGELEITHAIQHLIDNGADIQSMVIEGYWKDTGNVADMLEVNRTVLEDL 239

Query: 239 EREIK--VETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSVGNNVV 296
           E  I+  V+    +IGRV + EGA++  N+ I GPA+IG    I ++YIGP+TSVG+N  
Sbjct: 240 EPRIEGTVDEHTVVIGRVVVGEGARV-TNSRIMGPAIIGAGPEISDSYIGPFTSVGDNCR 298

Query: 297 IEDTEVEDSIIMDGSVIIGAGRIIESIIGKEVRIVRGDGHPLGRRLIVGDKSQLTL 352
           I  +E+E SI++  S I G  RI  S+IG+ V++ +    P   R ++GD S++ +
Sbjct: 299 ITGSEMEFSIMLAESAITGVRRIEGSLIGRNVQVTQSLHAPNAHRFVLGDHSKVEI 354


>pir||T30872 dNDP-glucose synthase - Streptomyces viridochromogenes
           >gi|1911169|emb|CAA72714.1| (Y11985) dNDP-glucose
           synthase [Streptomyces viridochromogenes]
           Length = 355
           
 Score =  324 bits (821), Expect = 1e-87
 Identities = 159/353 (45%), Positives = 245/353 (69%), Gaps = 5/353 (1%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MKALIL GG G+RLRP+T++  KQL+PVAN+ VL Y ++ + EAGI E+GI+VG    ++
Sbjct: 1   MKALILVGGVGSRLRPITHTSAKQLVPVANRTVLSYVLDSIKEAGISEVGIVVGATAAEI 60

Query: 61  IETV-KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKEH 119
             +V    ++  ++ +I Q  P+GLA A+LV+RD+LG+DDFVMYLGDN + +GIV     
Sbjct: 61  QASVGDGAEFGLDVTYIQQDAPRGLADAVLVSRDFLGDDDFVMYLGDNYVVDGIVDFVAD 120

Query: 120 FEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPIIH 179
           F +    A ++L  V +P++FGVAEL E+G+ +  ++EKP+ P S+LA+VG+Y F   +H
Sbjct: 121 FRRDKPAAQVMLARVADPRRFGVAELDENGR-VTAVVEKPQDPRSDLAIVGVYAFSSAVH 179

Query: 180 EAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLDEIE 239
           EAV  I+PSWRNELEITDA+QWL D+G++VG T +  +WKD     D+LE NR +L+ +E
Sbjct: 180 EAVAGIRPSWRNELEITDALQWLADHGHEVGSTVIDRYWKDVASVTDVLEMNRHLLESLE 239

Query: 240 REI--KVETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSVGNNVVI 297
             I  +V+  ++++GRV +E GAKI  + I+ GPAVIG + V++++Y+GP+TS+  N  +
Sbjct: 240 TRIDGEVDEASELVGRVVVEAGAKISGSRIV-GPAVIGPDTVVQDSYLGPFTSIEGNCRV 298

Query: 298 EDTEVEDSIIMDGSVIIGAGRIIESIIGKEVRIVRGDGHPLGRRLIVGDKSQL 350
             +E++ SI++ G+ I G  R+ +S+IG+E  +          RL++GD S++
Sbjct: 299 AHSEIQYSIVLRGASIEGVARVEDSVIGRETEVNAAPRTSTAHRLVLGDHSRV 351


>emb|CAA07386.1| (AJ006985) StrD [Streptomyces glaucescens]
           Length = 356
           
 Score =  321 bits (813), Expect = 1e-86
 Identities = 166/352 (47%), Positives = 231/352 (65%), Gaps = 6/352 (1%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MKAL+L+GG G RLRP+T++  KQL+PVANKPVLFY +E +  AGI ++GI+VG    ++
Sbjct: 1   MKALVLAGGAGPRLRPITHTSAKQLVPVANKPVLFYGLEAIAAAGITDVGIVVGDTVAEI 60

Query: 61  IETV-KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKEH 119
            E V     +  ++ +I Q +P GL H + ++RDYLG+DDF MYLGDN +  GI +    
Sbjct: 61  TEAVGDGSKFGLDVTYIPQRKPLGLGHGVRISRDYLGDDDFAMYLGDNFVVGGIDQPIRA 120

Query: 120 FEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPIIH 179
           F     DA +LL  V +P+ FGVAEL E G+ ++ L EKP HP S+LALVG+Y F P IH
Sbjct: 121 FRTHRPDAHLLLTRVSDPRSFGVAELDERGR-VRHLEEKPTHPGSDLALVGVYLFSPAIH 179

Query: 180 EAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLDEIE 239
           EAVR I+PSWR ELEIT A+QWLID G  V  T ++G+WKDTG   D+LE NRLVL+ +E
Sbjct: 180 EAVRAIEPSWRGELEITHAVQWLIDEGKDVRSTLISGYWKDTGNVTDMLEVNRLVLETVE 239

Query: 240 REI--KVETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSVGNNVVI 297
                 V+  +++IGRV+++EGA I  + +I GP V+G    I ++Y+GP+TS+    ++
Sbjct: 240 PRCDGDVDEDSELIGRVRVDEGAVIRNSRVI-GPVVVGSGTTITDSYVGPFTSIAEGCLV 298

Query: 298 EDTEVEDS-IIMDGSVIIGAGRIIESIIGKEVRIVRGDGHPLGRRLIVGDKS 348
           ED     S  ++  + I G  RI  S+IG+ VR+      P   RL++GD S
Sbjct: 299 EDQPSWSSPFVLRNASISGVRRIEASLIGRHVRVTAAPPVPHAHRLVLGDHS 350


>gb|AAD13545.1| (AF080235) NDP-hexose synthetase homolog [Streptomyces cyanogenus]
           Length = 355
           
 Score =  310 bits (787), Expect = 1e-83
 Identities = 162/353 (45%), Positives = 236/353 (65%), Gaps = 5/353 (1%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MKAL+LSGG GTRLRP ++S  KQLIP+ANKPVL + + +V + G+ EIG+IVG   EQ+
Sbjct: 1   MKALVLSGGSGTRLRPFSHSMPKQLIPIANKPVLEHVLRNVRDLGVTEIGVIVGDRAEQI 60

Query: 61  IETVKSVD-WDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKEH 119
              +         I +I Q  P GLAH + +AR +LG+DDFVMYLGDN+L EG+ R  + 
Sbjct: 61  QAVIGDGSALGVEITYIPQEAPLGLAHCVELARPFLGDDDFVMYLGDNMLPEGVERIADE 120

Query: 120 FEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPIIH 179
           F      A +++ +VP+P+ FGVAEL+ DG+ ++RL+EKP+ P S+LAL+G+YFF P IH
Sbjct: 121 FTAGRPAAQVVVHKVPDPRAFGVAELAADGR-VERLVEKPQEPKSDLALIGVYFFTPAIH 179

Query: 180 EAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLDEIE 239
           +AV  I+PS R ELEITDAIQWL+ NG +    +  G+WKDTG+ ED+LE NR +LD+++
Sbjct: 180 KAVAAIEPSARGELEITDAIQWLVANGDRFKANEYKGYWKDTGRIEDVLECNRKLLDDLK 239

Query: 240 --REIKVETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSVGNNVVI 297
              E +V+  + +IG V +E G K      I+GP VIG  +V+++++IGP+TS+G +V +
Sbjct: 240 PATEGEVDAASTLIGTVVVEAGPK-SSAPAIEGPVVIGAGSVVKDSHIGPHTSIGRDVRL 298

Query: 298 EDTEVEDSIIMDGSVIIGAGRIIESIIGKEVRIVRGDGHPLGRRLIVGDKSQL 350
             T +E SI +D + I     +  S+IG+   +   D      RL+VGD +++
Sbjct: 299 TGTSIEYSIALDDATISHVRDLHSSVIGRSASVGPSDRSTRHHRLVVGDHTRV 351


>pir||T46521 probable dTDP-1-glucose synthase [imported] - Streptomyces
           violaceoruber >gi|4218548|emb|CAA09637.1| (AJ011500)
           putative dTDP-1-glucose synthase [Streptomyces
           violaceoruber]
           Length = 353
           
 Score =  306 bits (775), Expect = 3e-82
 Identities = 154/352 (43%), Positives = 232/352 (65%), Gaps = 7/352 (1%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MKALILSGG GTRLRP TYS  KQL+PVANKP+L + +E+V   G+ E+ ++VG   ++V
Sbjct: 1   MKALILSGGMGTRLRPFTYSMPKQLVPVANKPILVHCLENVRAIGVEEVAVVVGDRADEV 60

Query: 61  IETVKSVD-WDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKEH 119
              V     +  ++ ++ Q  P GLAH + +A ++LG++DFVMYLGDNIL EGI      
Sbjct: 61  RAVVGDGSAFGLDVTYLQQEAPLGLAHCVSIAEEFLGDEDFVMYLGDNILAEGIAESARA 120

Query: 120 FEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPIIH 179
           F      A +LL +V +P+ +GVAE    G+ +  L+EKP+ P S+LA++G+YFF   +H
Sbjct: 121 FRDERSAARLLLTKVADPRAYGVAETDATGR-VHALVEKPERPRSDLAVIGVYFFTAAVH 179

Query: 180 EAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLDEIE 239
           +AVR I+PS R ELEITDAIQ+L++ G +V   + TG+WKDTG P+DLL+ NR++L  + 
Sbjct: 180 DAVRAIEPSARGELEITDAIQYLVERGDRVVADEYTGYWKDTGSPDDLLDCNRVLLGRLR 239

Query: 240 REI--KVETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSVGNNVVI 297
             +  +V+  + + G V +E G    ++ ++ GP V+G  +V+R + +GPYT++G + V+
Sbjct: 240 PGVHGEVDAASTVEGTVVVEAGRSWSDSRLV-GPLVVGAGSVVRGSELGPYTALGRDCVL 298

Query: 298 EDTEVEDSIIMDGSVIIGAGRIIESIIGKEVRIVRGDGHPLGRRLIVGDKSQ 349
           ED  + DSI++DG  I G   +  S+IG+   +  G+    GRRLI+GD +Q
Sbjct: 299 EDAGIRDSIVLDGVSIQGVRGLSGSLIGRSAAVRTGEA--AGRRLIIGDHTQ 348


>gb|AAB50923.1| (L47163) glucose-1-phosphate thymidylyltransferase [Streptomyces
           peucetius] >gi|1588468|prf||2208414A glucose phosphate
           thymidylate transferase [Streptomyces peucetius]
           Length = 351
           
 Score =  294 bits (745), Expect = 1e-78
 Identities = 163/359 (45%), Positives = 226/359 (62%), Gaps = 17/359 (4%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MKAL+LSGG GTRLRP T++  KQL+PVANKPVL+Y +ED+ +A I E+GI+VG    ++
Sbjct: 1   MKALVLSGGSGTRLRPFTHTSPKQLVPVANKPVLYYVLEDIAQASITEVGIVVGETSNEI 60

Query: 61  IETVKSVD-WDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKEH 119
            + V S D +   + ++ Q  P GLAHA+L+ARDYLG +DFVMYLGDN +  GI  +   
Sbjct: 61  RKAVGSGDRFGLRVTYLPQEAPLGLAHAVLIARDYLGEEDFVMYLGDNFVVGGIAGNSST 120

Query: 120 FEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPIIH 179
           F     DA ILL  V +P  FGVAE+  DG+ +  L EKP+HP S+LA+VGIY F P++H
Sbjct: 121 FRAERPDAQILLTRVSDPSSFGVAEIGCDGRVVA-LEEKPRHPRSDLAVVGIYLFTPVVH 179

Query: 180 EAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLDEIE 239
           EAVR + PS R ELEITDA+QWL+D  Y V +T ++G+WKDTG   D+LE NR VLD IE
Sbjct: 180 EAVRALTPSRRGELEITDALQWLLDGPYDVRYTTISGYWKDTGNVADMLEVNRAVLDGIE 239

Query: 240 --REIKVETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSVGNNVVI 297
              E + +  ++++GRV+IE GA+I  + I+      GR     +A          +V  
Sbjct: 240 PGMEGQADAASELVGRVRIEAGAQIRASRIVARRHRAGRVTDRTSAL---------HVDR 290

Query: 298 EDTEVE---DSIIMDGSV-IIGAGRIIESIIGKEVRIVRGDGHPLGRRLIVGDKSQLTL 352
            D  +E    S+   G +   G  R+  S++G+ V +      P G RLI+GD S++ +
Sbjct: 291 GDCSIETARSSLHHAGRLPAHGTRRVQHSLLGRNVTVAPAPRVPAGSRLILGDDSRVEI 349


>gb|AAF00210.1|AF164960_6 (AF164960) dNDP-glucose synthetase [Streptomyces fradiae]
           Length = 355
           
 Score =  291 bits (736), Expect = 1e-77
 Identities = 151/354 (42%), Positives = 230/354 (64%), Gaps = 7/354 (1%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MKAL+L+GG GTRLRP +YS  KQLIP+AN PVL + + ++ E G+ E G+IVG    ++
Sbjct: 1   MKALVLAGGSGTRLRPFSYSMPKQLIPIANTPVLVHVLRNLRELGVTEAGVIVGNRGPEI 60

Query: 61  IETV-KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKEH 119
              +    ++   + +I Q  P+GLAH + + RD+L +DDFVMYLGDN+L +G+V  +  
Sbjct: 61  SAVLGDGAEFGMRVTYIPQDAPRGLAHTVAITRDFLCDDDFVMYLGDNMLPDGVVDMRGG 120

Query: 120 FEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPIIH 179
             +      +++ +VP+P+ FGVAEL   G+ + RL+EKP+ P S++ALVG+YFF   IH
Sbjct: 121 IHRPSAGGQVVVYKVPDPRSFGVAELGPQGEVL-RLVEKPRDPRSDMALVGVYFFTAAIH 179

Query: 180 EAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLDEIE 239
           +AV  I+PS R ELEITDAIQWL+ +G  V  ++  G+WKDTG  ED+LE NR +LD + 
Sbjct: 180 DAVAAIEPSARGELEITDAIQWLVSSGADVRASQYDGYWKDTGNVEDVLECNRHLLDGLG 239

Query: 240 REI--KVETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSVGNNVVI 297
             +   V+  + + G V IE GAK+  + I+ G A+IG   V++++++GP+ S+G    +
Sbjct: 240 ARMDGTVDAASVLTGEVVIEPGAKVVRSRIM-GAAIIGAGTVVQDSHVGPHASIGRRCTV 298

Query: 298 EDTEVEDSIIMDGSVIIGAGRIIESIIGKEVRIVRGDGHPLGR-RLIVGDKSQL 350
            D+ VE+SI +D + + G   +  S+IG+    V G G    R RL+VGD +++
Sbjct: 299 TDSRVENSIALDEASVTGVRGLRNSLIGRSAS-VGGTGQENERYRLVVGDHTRV 351


>pir||S58687 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) strD -
           Streptomyces violaceoruber >gi|763512|gb|AAA99940.1|
           (L37334) dTDP-glucose synthetase [Streptomyces
           violaceoruber]
           Length = 352
           
 Score =  289 bits (733), Expect = 2e-77
 Identities = 149/352 (42%), Positives = 227/352 (64%), Gaps = 8/352 (2%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MKALI     G RLRP TYS  KQL+PVANKP+L + +E+V   G+ E+ ++VG   ++V
Sbjct: 1   MKALICPED-GDRLRPFTYSMPKQLVPVANKPILVHCLENVRAIGVEEVAVVVGDRADEV 59

Query: 61  IETVKSVD-WDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKEH 119
              V     +  ++ ++ Q  P GLAH + +A ++LG++DFVMYLGDNIL EGI      
Sbjct: 60  RAVVGDGSAFGLDVTYLQQEAPLGLAHCVSIAEEFLGDEDFVMYLGDNILAEGIAESARA 119

Query: 120 FEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPIIH 179
           F      A +LL +V +P+ +GVAE    G+ +  L+EKP+ P S+LA++G+YFF   +H
Sbjct: 120 FRDERSAARLLLTKVADPRAYGVAETDATGR-VHALVEKPERPRSDLAVIGVYFFTAAVH 178

Query: 180 EAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLDEIE 239
           +AVR I+PS R ELEITDAIQ+L++ G +V   + TG+WKDTG P+DLL+ NR++L  + 
Sbjct: 179 DAVRAIEPSARGELEITDAIQYLVERGDRVVADEYTGYWKDTGSPDDLLDCNRVLLGRLR 238

Query: 240 REI--KVETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSVGNNVVI 297
             +  +V+  + + G V +E G    ++ ++ GP V+G  +V+R + +GPYT++G + V+
Sbjct: 239 PGVHGEVDAASTVEGTVVVEAGRSWSDSRLV-GPLVVGAGSVVRGSELGPYTALGRDCVL 297

Query: 298 EDTEVEDSIIMDGSVIIGAGRIIESIIGKEVRIVRGDGHPLGRRLIVGDKSQ 349
           ED  + DSI++DG  I G   +  S+IG+   +  G+    GRRLI+GD +Q
Sbjct: 298 EDAGIRDSIVLDGVSIQGVRGLSGSLIGRSAAVRTGEA--AGRRLIIGDHTQ 347


>pir||A75596 probable glucose-1-phosphate thymidylyltransferase - Deinococcus
           radiodurans (strain R1)
           >gi|6460571|gb|AAF12277.1|AE001862_103 (AE001862)
           glucose-1-phosphate thymidylyltransferase, putative
           [Deinococcus radiodurans]
           Length = 361
           
 Score =  275 bits (695), Expect = 7e-73
 Identities = 151/355 (42%), Positives = 224/355 (62%), Gaps = 7/355 (1%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGP-NKEQ 59
           MKALI + G GTRLRPLT+++ K ++ VA +P++ +AI  + EAGI +IGI+V    +++
Sbjct: 10  MKALIPAAGLGTRLRPLTFTRPKPVLRVAGQPIIRHAIRTLTEAGITDIGIVVSDVTRDE 69

Query: 60  VIETVKSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKEH 119
           +   V+ +  D  +  I Q +  GL HA+L AR+++G DDF +YLGDN+   G     E 
Sbjct: 70  IQHAVREIR-DVKLTLINQHDQLGLGHAVLTAREWVGQDDFCVYLGDNLFEFGARPFIES 128

Query: 120 FEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPIIH 179
           F +    A I L +V +P  FGVAEL  DG+ I RL+EKPK PPSNLA+ G+Y F P I 
Sbjct: 129 FHQKHPAALIALVKVADPTAFGVAEL--DGEQITRLVEKPKDPPSNLAVAGLYCFTPQIF 186

Query: 180 EAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLDEIE 239
           E +  + PS R E EITD IQ LI+ G  V   +V GWWKDTG+P DLL+ANRL+L++IE
Sbjct: 187 EVLDVMPPSARGEYEITDGIQGLIERGQTVVGQRVEGWWKDTGRPADLLDANRLLLEQIE 246

Query: 240 REIKVETR-AKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSVGNNVVIE 298
            +++ +   +++ GRV +   +K+  + I+ GP +IG + +I +AYIGP+TS+G   VI 
Sbjct: 247 TDVQGDMEGSRMTGRVIVPASSKVLRSKIV-GPVIIGEDVIIEDAYIGPFTSIGRGTVIR 305

Query: 299 DTEVEDSIIMDGSVIIGA-GRIIESIIGKEVRIVRGDGHPLGRRLIVGDKSQLTL 352
           + E+E S +  G VI     R+ + +IG + ++  G   P   +L + D S + L
Sbjct: 306 NAEIEHSSVDSGVVIENVQTRLQDCLIGVKAQVRGGRTLPKTHKLTISDASVVEL 360


>emb|CAB57473.1| (Y18930) glucose-1-phosphate thymidylyltransferase (graD-2)
           [Sulfolobus solfataricus]
           Length = 344
           
 Score =  270 bits (684), Expect = 1e-71
 Identities = 157/356 (44%), Positives = 233/356 (65%), Gaps = 16/356 (4%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKE-Q 59
           M+A+IL GG GTRLRPLT++  KQLI VA KPV  + +E + +AGI ++ I++G N   +
Sbjct: 1   MEAVILHGGQGTRLRPLTHTGPKQLIKVAGKPVSQWVLEQIRDAGIRDVIIVLGDNAPTR 60

Query: 60  VIETV-KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKE 118
           V+E       +   I ++YQG+ +GLA A+   +D + +D F++YLGDN++   + +   
Sbjct: 61  VVEYYGDGSKFGVRITYVYQGKARGLADAVYKVKDVV-SDKFLVYLGDNLVPYDLSK--- 116

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPII 178
            F      ASILL +V NP +FGVA + +DG+ +K LIEKPK   S+LALVG+Y F   I
Sbjct: 117 -FSSFKGSASILLAKVNNPNRFGVAVI-KDGRVVK-LIEKPKEQISDLALVGVYGFTREI 173

Query: 179 HEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLDE- 237
            + +  +KPSWR ELEITDAIQ LID G +V +  + GWWKDTG P+D+LEAN  +LD  
Sbjct: 174 FDVIESLKPSWRGELEITDAIQGLIDRGREVNYEIIQGWWKDTGTPKDILEANAFLLDRY 233

Query: 238 IEREIK-VETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSVGNNVV 296
            E  I+ V   + + G+V IE+GA I +N++++GP  IGR+  I N+YIGP+TS+G+   
Sbjct: 234 AESRIEGVVDNSTVDGKVIIEKGAVI-KNSVVRGPTYIGRDTKIINSYIGPFTSIGDQSE 292

Query: 297 IEDTEVEDSIIMDGSVIIGAGRIIESIIGKEVRIVRGDGHPLGRRLIVGDKSQLTL 352
           I D+E+E S+I+DG  I G   +++S+IG    + +G      ++LI+G+ S + L
Sbjct: 293 ITDSEIEYSVILDGVKIRGV-TLMDSLIGNNSTVEKGG---RWQKLIIGENSSVIL 344


>gb|AAK41126.1| Sugar phosphate nucleotydyl transferase [Sulfolobus solfataricus]
           Length = 344
           
 Score =  270 bits (684), Expect = 1e-71
 Identities = 157/356 (44%), Positives = 233/356 (65%), Gaps = 16/356 (4%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKE-Q 59
           M+A+IL GG GTRLRPLT++  KQLI VA KPV  + +E + +AGI ++ I++G N   +
Sbjct: 1   MEAVILHGGQGTRLRPLTHTGPKQLIKVAGKPVSQWVLEQIRDAGIRDVIIVLGDNAPTR 60

Query: 60  VIETV-KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKE 118
           V+E       +   I ++YQG+ +GLA A+   +D + +D F++YLGDN++   + +   
Sbjct: 61  VVEYYGDGSKFGVRITYVYQGKARGLADAVYKVKDVV-SDKFLVYLGDNLVPYDLSK--- 116

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPII 178
            F      ASILL +V NP +FGVA + +DG+ +K LIEKPK   S+LALVG+Y F   I
Sbjct: 117 -FSSFKGSASILLAKVNNPNRFGVAVI-KDGRVVK-LIEKPKEQISDLALVGVYGFTREI 173

Query: 179 HEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLDE- 237
            + +  +KPSWR ELEITDAIQ LID G +V +  + GWWKDTG P+D+LEAN  +LD  
Sbjct: 174 FDVIESLKPSWRGELEITDAIQGLIDRGREVNYEIIQGWWKDTGTPKDILEANAFLLDRY 233

Query: 238 IEREIK-VETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSVGNNVV 296
            E  I+ V   + + G+V IE+GA I +N++++GP  IGR+  I N+YIGP+TS+G+   
Sbjct: 234 AESRIEGVVDNSTVDGKVIIEKGAVI-KNSVVRGPTYIGRDTKIINSYIGPFTSIGDQSE 292

Query: 297 IEDTEVEDSIIMDGSVIIGAGRIIESIIGKEVRIVRGDGHPLGRRLIVGDKSQLTL 352
           I D+E+E S+I+DG  I G   +++S+IG    + +G      ++LI+G+ S + L
Sbjct: 293 ITDSEIEYSVILDGVKIRGV-TLMDSLIGNNSTVEKGG---RWQKLIIGENSSVIL 344


>gb|AAK41974.1| Sugar phosphate nucleotydyl transferase [Sulfolobus solfataricus]
           Length = 344
           
 Score =  263 bits (665), Expect = 2e-69
 Identities = 153/356 (42%), Positives = 234/356 (64%), Gaps = 16/356 (4%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKE-Q 59
           M+A+IL GG GTRLRPLT++  KQLI VA KP+  + +E + ++GI +I +I+G N   +
Sbjct: 1   MEAVILHGGQGTRLRPLTHTGPKQLIKVAGKPISQWVLEQIRDSGIKDILLILGDNTPTR 60

Query: 60  VIETV-KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKE 118
           V++       +  NI ++YQG+ +GLA A+   +D L ++ F++YLGDN++   + +   
Sbjct: 61  VVDYYGDGSKFGVNITYVYQGKARGLADAVYRVKD-LVSEKFLVYLGDNLVFYDLRK--- 116

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPII 178
            F      ASILL +V NP +FGVA ++E+   + RL+EKPK   S+LALVG+Y F   I
Sbjct: 117 -FLSFKGSASILLAKVDNPNRFGVAVINEN--KVIRLVEKPKEKISDLALVGVYGFTDEI 173

Query: 179 HEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLDE- 237
            E +  +KPSWR ELEITDAIQ LI+ G +V +  + GWWKDTG P+D+LEAN  +LD  
Sbjct: 174 FEVIEKLKPSWRGELEITDAIQGLINEGKEVNYEIIQGWWKDTGTPKDILEANSFLLDRY 233

Query: 238 IEREIKVET-RAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSVGNNVV 296
            ER+I+ E   + I GRV +E+GA + +N++I+GPA IG++  I N+YIGP+TS+G+   
Sbjct: 234 AERKIEGEVENSTIDGRVILEKGAVV-KNSVIRGPAYIGKDTKIINSYIGPFTSIGDLSE 292

Query: 297 IEDTEVEDSIIMDGSVIIGAGRIIESIIGKEVRIVRGDGHPLGRRLIVGDKSQLTL 352
           I  +E+E S+I+D   I G   +++S+IG    + +G      ++LI+G+ S + +
Sbjct: 293 ISGSEIEYSVILDNVRIKGVS-LMDSLIGNNSTVEKG---TKWQKLIIGENSSVII 344


>pir||A72589 probable glucose-1-phosphate thymidylyltransferase APE1181 -
           Aeropyrum pernix (strain K1) >gi|5104853|dbj|BAA80167.1|
           (AP000061) 355aa long hypothetical glucose-1-phosphate
           thymidylyltransferase [Aeropyrum pernix]
           Length = 355
           
 Score =  238 bits (602), Expect = 6e-62
 Identities = 138/359 (38%), Positives = 225/359 (62%), Gaps = 12/359 (3%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           +K LIL+ G G+RLRP T+S+ K LIP+  KP++ YAI+D++   + +IG++VG   +++
Sbjct: 2   VKGLILAAGEGSRLRPFTFSRPKHLIPLLGKPIIQYAIDDLVSINVRDIGVVVGYFGDKI 61

Query: 61  IETV-KSVDWDANIEFIYQGEPKGLAHAILVA-RDYLGNDDFVMYLGDNILREGIVRHKE 118
            E + +   + A   +I Q +  G+AHAI  A +    + +F++YLGDNIL  GI RH +
Sbjct: 62  KEFLGEDSRFGAKFTYIVQKKRLGIAHAIYRAIKQGFIDKEFIVYLGDNILSGGISRHVK 121

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRP-- 176
            + ++  +  ILL +V +P +FG+A L  DGK +K L+EKP+   S+LA+VG+Y FR   
Sbjct: 122 SWGEAGSEVHILLTKVRDPGRFGIAVL-RDGKILK-LVEKPQEHISDLAVVGVYMFRDPE 179

Query: 177 IIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLD 236
           ++ +A   +KPSWR E EITD IQW +D GYKV ++ VTGWWKD G  E LL+A  L+LD
Sbjct: 180 LVAKAFSTLKPSWRGEYEITDLIQWFVDKGYKVTFSLVTGWWKDVGTYEGLLDAIYLLLD 239

Query: 237 EIEREIKVETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVI-RNAYIGPYTSVGNNV 295
            ++  ++ +   ++ GRV +EEGA ++    + GPA IG++  I R+  +  Y S+    
Sbjct: 240 NVKPRVEGKIEGEVRGRVVVEEGAIVEGT--VHGPAYIGKDVYIGRSGLVEHYVSMEQGS 297

Query: 296 VIEDTEVEDSIIMDGS-VIIGAGRIIESIIGKEVRIVRGDGHPLGR-RLIVGDKSQLTL 352
            I    V  S+I+D S + +   R+++S++G +  I++ +    G  +L++ D S++ L
Sbjct: 298 RIISGTVARSMILDESELYLNKARLVDSVVGPK-SIIKSNREIYGDIKLVISDYSKVFL 355


>gb|AAD31893.2|AF144042_1 (AF144042) dTDP-glucose synthase [Streptomyces rimosus subsp.
           paromomycinus]
           Length = 256
           
 Score =  211 bits (531), Expect = 1e-53
 Identities = 113/256 (44%), Positives = 167/256 (65%), Gaps = 4/256 (1%)

Query: 99  DFVMYLGDNILREGIVRHKEHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEK 158
           DFVMYLGDN +  GI    + F  +     +L+ +VP+P  FGVAE++ +G+ + RL EK
Sbjct: 1   DFVMYLGDNFVVGGIAGVVQRFRTTRCGTRLLVTKVPDPSPFGVAEVTPEGRVV-RLEEK 59

Query: 159 PKHPPSNLALVGIYFFRPIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWW 218
           P  P S+LA+VG+Y F   +H AV  I+PS R ELEITDAIQWLID+G+ V    + G+W
Sbjct: 60  PARPRSDLAVVGVYLFTSAVHRAVAAIEPSARGELEITDAIQWLIDSGHDVVAETIDGYW 119

Query: 219 KDTGKPEDLLEANRLVLDEIEREIK--VETRAKIIGRVKIEEGAKIDENTIIKGPAVIGR 276
           KDTG   D+LE N+ VL ++E  ++  V++ + ++G V+IE GA+I  + I+ GPAVIG 
Sbjct: 120 KDTGDVADMLEVNQRVLADLEPAVRGAVDSASVLLGPVRIEPGAEIVRSRIV-GPAVIGA 178

Query: 277 NAVIRNAYIGPYTSVGNNVVIEDTEVEDSIIMDGSVIIGAGRIIESIIGKEVRIVRGDGH 336
           +  +R++ IGP TSV     + +++VE SI +  + I GAGRI  S+IG+ V++      
Sbjct: 179 HTTVRDSRIGPATSVAEGCAVIESDVEFSIALRDARITGAGRIEGSLIGRAVQVTGAART 238

Query: 337 PLGRRLIVGDKSQLTL 352
           P   RL++GD S++ L
Sbjct: 239 PQAHRLVLGDHSRIQL 254


>pir||D64437 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) -
           Methanococcus jannaschii >gi|1591746|gb|AAB99104.1|
           (U67553) glucose-1-phosphate thymidylyltransferase
           (strD) [Methanococcus jannaschii]
           Length = 408
           
 Score =  206 bits (520), Expect = 2e-52
 Identities = 136/330 (41%), Positives = 197/330 (59%), Gaps = 17/330 (5%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           M A+IL  G G RLRPLT ++ K +IP+A KP+L + IE V E  +  I +IV   KE++
Sbjct: 1   MDAIILCAGKGERLRPLTENRPKPMIPIAGKPILQHIIEKV-EDLVDNIYLIVKYKKEKI 59

Query: 61  IETVKSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKEHF 120
           ++  K+      I+F+ QGE  G   A+L A+DY+ +D+F++  GD I  + +    E F
Sbjct: 60  VDYFKN---HPKIKFLEQGEIDGTGQAVLTAKDYV-DDEFLVINGDIIFEDDL----EEF 111

Query: 121 EKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPIIHE 180
            K  Y  ++ + EV NP+ FGV  L ++   I+ L EKP++P SNL   GIY F   I E
Sbjct: 112 LKYKY--AVAVKEVKNPENFGVVVLDDENNIIE-LQEKPENPKSNLINAGIYKFDKKIFE 168

Query: 181 AVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLDEIER 240
            +   K S R E E+TDAI+ LI    KV   K+ G+W D G+P D+LEAN+ +LD+I  
Sbjct: 169 LIEKTKISERGERELTDAIKHLIKE-EKVKGIKLNGYWNDVGRPWDILEANKYLLDKINT 227

Query: 241 EI--KVETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRN-AYIGPYTSVGNNVVI 297
           +I  K+E    I G V IEEGA +  N++I+GPA+I + AV+   AYI PYT +  N  +
Sbjct: 228 DIKGKIEENVVIKGEVIIEEGAIVKANSVIEGPAIIKKGAVVGPLAYIRPYTVLMENTFV 287

Query: 298 -EDTEVEDSIIMDGSVIIGAGRIIESIIGK 326
              +EV+ SIIM  + I     + +SIIG+
Sbjct: 288 GNSSEVKASIIMKNTKIPHLSYVGDSIIGE 317


>gb|AAG23610.1|AF244661_1 (AF244661) glucose-1-phosphate thymidylyltransferase
           [Carboxydothermus hydrogenoformans]
           Length = 197
           
 Score =  203 bits (512), Expect = 2e-51
 Identities = 102/189 (53%), Positives = 136/189 (70%), Gaps = 2/189 (1%)

Query: 41  VIEAGIHEIGIIVGPNK-EQVIETVKSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDD 99
           ++ AGI +IG+I+ P   E++ +++ +  + A   FI Q +P GLAHA+ VA+DYL +DD
Sbjct: 2   LVNAGITDIGVIIAPETGEEIKKSITNAGFPAKFTFILQEKPLGLAHAVKVAKDYLEDDD 61

Query: 100 FVMYLGDNILREGIVRHKEHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKP 159
           F+MYLGDN++  GI    E ++++ YDA+ILL EV +P +FGVA + E+ K ++RLIEKP
Sbjct: 62  FIMYLGDNLINSGIKEFVEEYKENRYDATILLKEVQDPTRFGVAVVDENFK-VQRLIEKP 120

Query: 160 KHPPSNLALVGIYFFRPIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWK 219
           K PPSNLALVGIY F P I  A+  IKPSWR ELEITDAIQ LI +G  V   K+TGWW 
Sbjct: 121 KEPPSNLALVGIYIFSPKIFSAIDRIKPSWRGELEITDAIQELITSGGMVQAHKITGWWL 180

Query: 220 DTGKPEDLL 228
           DTGK + LL
Sbjct: 181 DTGKKDHLL 189


>gb|AAG23575.1|AF244626_1 (AF244626) glucose-1-P thymidylyltransferase [Carboxydothermus
           hydrogenoformans]
           Length = 203
           
 Score =  199 bits (502), Expect = 3e-50
 Identities = 101/187 (54%), Positives = 133/187 (71%), Gaps = 2/187 (1%)

Query: 38  IEDVIEAGIHEIGIIVGPNK-EQVIETVKSVDWDANIEFIYQGEPKGLAHAILVARDYLG 96
           IED+I+AGI +IG+I+ P   E + +++ +  + A   FI Q +P GLAHA+ VA+DYL 
Sbjct: 8   IEDIIDAGITDIGVIIAPETGEXIKKSITNAGFPAKFTFILQEKPLGLAHAVKVAKDYLE 67

Query: 97  NDDFVMYLGDNILREGIVRHKEHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLI 156
           +DDF+MYLGDN++  GI    E ++++ YDA+ILL EV +P +FGVA + E+   ++RLI
Sbjct: 68  DDDFIMYLGDNLINSGIKEFVEEYKENRYDATILLKEVQDPTRFGVAVVDENF-XVQRLI 126

Query: 157 EKPKHPPSNLALVGIYFFRPIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTG 216
           EKPK PPSNLALVGIY F P I  A+  IKPSWR ELEITDAIQ LI  G  V    +TG
Sbjct: 127 EKPKEPPSNLALVGIYIFSPXIFSAMTGIKPSWRGELEITDAIQELIYQGGVVKAHNITG 186

Query: 217 WWKDTGK 223
           WW DTG+
Sbjct: 187 WWLDTGE 193


>gb|AAD13560.1| (AF080235) NDP-hexose synthetase homolog [Streptomyces cyanogenus]
           Length = 328
           
 Score =  192 bits (482), Expect = 7e-48
 Identities = 118/356 (33%), Positives = 192/356 (53%), Gaps = 38/356 (10%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MKAL+LSGG GTRLRPLT+S  KQLIP+A +PV+ + ++ V + G+ E GI+V    EQ+
Sbjct: 1   MKALVLSGGTGTRLRPLTHSLPKQLIPLAGRPVVAHVLDSVRDLGVRETGIVVTDGGEQI 60

Query: 61  IETVKSVDWDA-NIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKEH 119
            + +        ++ +  Q  P+G  HA+ +ARD+LG+DDFV+Y GD ++ E I      
Sbjct: 61  EQALGDGSRSGLSLTYFRQDTPRGFGHALSLARDFLGDDDFVVYRGDTLVTESIADRAAA 120

Query: 120 FEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPIIH 179
           F      A +++     P+     EL                         ++FF P +H
Sbjct: 121 FAAERPAAGVVV-----PEAAPDVEL-------------------------VHFFTPAVH 150

Query: 180 EAVRHIKPSWRNE-LEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLDEI 238
           EAV  +      + +    A QWL  +G  V     TG+W+     ED+L A+R +LD +
Sbjct: 151 EAVAALAADRPGDAVTPAGAAQWLRAHGGDVRTGTYTGYWRRIASAEDVLAAHRTLLDGL 210

Query: 239 EREI--KVETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSVGNNVV 296
              +   V+ +++I G V IE GAK+   + I+GPAV+   A++  ++IGP+ ++G +  
Sbjct: 211 APAMDGDVDAQSRITGHVVIEPGAKV-VRSWIEGPAVVSAGALVEESHIGPHATIGRDCS 269

Query: 297 IEDTEVEDSIIMDGSVIIGAGRIIESIIGK--EVRIVRGDGHPLGRRLIVGDKSQL 350
           +  T V+DS++++G+ +   GR+  S+IG+   V     DG P  R L+VGD +++
Sbjct: 270 VHGTHVDDSLVLEGATVSPVGRLHGSLIGRFAHVSAAGRDGAP-RRSLVVGDHARV 324


>pir||G75020 glucose-1-phosphate thymidylyltransferase (grad-2) PAB1115 -
           Pyrococcus abyssi (strain Orsay)
           >gi|5459119|emb|CAB50605.1| (AJ248288)
           glucose-1-phosphate thymidylyltransferase (graD-2)
           [Pyrococcus abyssi]
           Length = 419
           
 Score =  190 bits (477), Expect = 3e-47
 Identities = 120/339 (35%), Positives = 196/339 (57%), Gaps = 10/339 (2%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MKA++L+ G G RLRPLT  + K ++ VANKP++ Y +E+ ++  + E  IIV   KE++
Sbjct: 1   MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILEN-LDPFVDEFIIIVKYMKEKI 59

Query: 61  IETVKSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKEH- 119
           IET+        I ++ Q E +G A AI  A+DY+  ++F    GD    +  +R   H 
Sbjct: 60  IETLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLLHV 119

Query: 120 FEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPIIH 179
           ++K+  +A++++ +  +  Q G+ +   +G  ++ ++EKP +    LA +GIY F P + 
Sbjct: 120 YKKTKANAALVVKKFDDLSQLGMVKT--EGGYVREIVEKPGNV-GGLANLGIYIFNPDVF 176

Query: 180 EAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVL-DEI 238
           E +   + S R E EITD I  +I +G KV + + +G+W D G+P DLLE N  +L  ++
Sbjct: 177 EFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKTKL 236

Query: 239 EREIK--VETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVI-RNAYIGPYTSVGNNV 295
           + +I+  VE  A II  V+I EG  +   + I GP  IG+N  I  N +I PYTS+G+N 
Sbjct: 237 KHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDNC 296

Query: 296 VIED-TEVEDSIIMDGSVIIGAGRIIESIIGKEVRIVRG 333
            I +  E+++SIIMD S       + +SI+G+   +  G
Sbjct: 297 HIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAG 335


>pir||E71207 probable glucose-1-phosphate thymidylyltransferase - Pyrococcus
           horikoshii >gi|3258369|dbj|BAA31052.1| (AP000007) 419aa
           long hypothetical glucose-1-phosphate
           thymidylyltransferase [Pyrococcus horikoshii]
           Length = 419
           
 Score =  183 bits (461), Expect = 2e-45
 Identities = 119/339 (35%), Positives = 189/339 (55%), Gaps = 10/339 (2%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MKA+IL+ G G RLRPLT  + K ++ +ANKP++ Y +E+ ++  + E  I+V   KE++
Sbjct: 1   MKAVILAAGKGERLRPLTDDRPKPILKIANKPIIEYILEN-LDPFVDEFIIVVKYKKEKI 59

Query: 61  IETVKSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKEH- 119
           IET+        I ++ QG+ +G A AI  A+D + +++F    GD    +  +R   H 
Sbjct: 60  IETLGDEFHGKPITYVVQGDEEGTARAIYSAKDAIIDEEFFAINGDIYFEQEAIRGLLHT 119

Query: 120 FEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPIIH 179
           + K   D  I++ +  N  Q G+ E+  +   +K++IEKP       A +GIY F   + 
Sbjct: 120 YRKMKADGGIVVKKFENLSQLGLVEVKNN--LVKKIIEKPGKM-EGFANLGIYIFNSEVF 176

Query: 180 EAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVL-DEI 238
           + +   + S R E EITD I  +I+ G ++ + +  G+W D G+P DLLE N  +L  ++
Sbjct: 177 DFIEETEKSERGEYEITDTINIMIERGKRIVYFEYKGFWSDIGRPWDLLEVNEYILKTKL 236

Query: 239 EREIK--VETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVI-RNAYIGPYTSVGNNV 295
           +  I+  VE  A II  V+I EG  +   + I GP  IG+N  I  N +I PYTS+G+N 
Sbjct: 237 KHNIRGTVEEGATIIPPVEIGEGTIVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDNC 296

Query: 296 VIED-TEVEDSIIMDGSVIIGAGRIIESIIGKEVRIVRG 333
            I +  EV++SIIMD S       + +SIIG+   +  G
Sbjct: 297 HIGNAVEVKNSIIMDNSNAPHLNYVGDSIIGENTNLGAG 335


>gb|AAK41040.1| Sugar phosphate nucleotydyl transferase [Sulfolobus solfataricus]
           Length = 407
           
 Score =  178 bits (448), Expect = 6e-44
 Identities = 118/338 (34%), Positives = 191/338 (55%), Gaps = 20/338 (5%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MKA++L+ G G RL P+T+++ K  +PV   P++   I  +++  I++I I++  N +  
Sbjct: 1   MKAVVLAAGKGERLEPITHTRPKPFVPVLETPLILRHIR-ILKKYINKIIIVINSNHKDY 59

Query: 61  IETVKSVDWDANIEFIYQGEPKGLAHAILVARDYL-GNDDFVMYLGDNILREGIVRHKEH 119
            +T++ V        + Q E KG A A+  A  YL G+++F++  GD +  E  +    +
Sbjct: 60  FKTIEGVS------LVEQTEGKGTAAALRAAEKYLEGDEEFLVIYGDLLFEEDALDKIVN 113

Query: 120 FEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPIIH 179
            E      +IL  E  +P++FGV     + + + R++EKP++PPSN+   GIY F   I 
Sbjct: 114 TEGE----AILARESEDPRKFGVIVKDSENRLV-RIVEKPENPPSNIINAGIYKFTYDIF 168

Query: 180 EAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLD-EI 238
             +  I  S R E E+TDA+  +   G KV      G W D G+P DL+EAN+++LD E 
Sbjct: 169 SYIDKISLSSRGEFELTDAVNLI---GNKVKVVTYNGIWLDIGRPWDLIEANKVLLDKEK 225

Query: 239 EREIKV-ETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVI-RNAYIGPYTSVGNNVV 296
           +R + V E   KI G+V IE+G  I   T I+GP  IG+N+VI  NAYI PY+ +G+NV 
Sbjct: 226 DRNLGVIEENVKIKGKVVIEDGVIIKSGTYIEGPVYIGKNSVIGPNAYIRPYSVIGSNVK 285

Query: 297 I-EDTEVEDSIIMDGSVIIGAGRIIESIIGKEVRIVRG 333
           +    E+++S+IM+ + I     + +S+I + V    G
Sbjct: 286 VGAFNEIKESVIMENAKIPHLSYVGDSVICEGVNFGAG 323


>emb|CAB57558.1| (Y18930) glucose-1-phosphate thymidylyltransferase [Sulfolobus
           solfataricus]
           Length = 407
           
 Score =  178 bits (448), Expect = 6e-44
 Identities = 118/338 (34%), Positives = 191/338 (55%), Gaps = 20/338 (5%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MKA++L+ G G RL P+T+++ K  +PV   P++   I  +++  I++I I++  N +  
Sbjct: 1   MKAVVLAAGKGERLEPITHTRPKPFVPVLETPLILRHIR-ILKKYINKIIIVINSNHKDY 59

Query: 61  IETVKSVDWDANIEFIYQGEPKGLAHAILVARDYL-GNDDFVMYLGDNILREGIVRHKEH 119
            +T++ V        + Q E KG A A+  A  YL G+++F++  GD +  E  +    +
Sbjct: 60  FKTIEGVS------LVEQTEGKGTAAALRAAEKYLEGDEEFLVIYGDLLFEEDALDKIVN 113

Query: 120 FEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPIIH 179
            E      +IL  E  +P++FGV     + + + R++EKP++PPSN+   GIY F   I 
Sbjct: 114 TEGE----AILARESEDPRKFGVIVKDSENRLV-RIVEKPENPPSNIINAGIYKFTYDIF 168

Query: 180 EAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLD-EI 238
             +  I  S R E E+TDA+  +   G KV      G W D G+P DL+EAN+++LD E 
Sbjct: 169 SYIDKISLSSRGEFELTDAVNLI---GNKVKVVTYNGIWLDIGRPWDLIEANKVLLDKEK 225

Query: 239 EREIKV-ETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVI-RNAYIGPYTSVGNNVV 296
           +R + V E   KI G+V IE+G  I   T I+GP  IG+N+VI  NAYI PY+ +G+NV 
Sbjct: 226 DRNLGVIEENVKIKGKVVIEDGVIIKSGTYIEGPVYIGKNSVIGPNAYIRPYSVIGSNVK 285

Query: 297 I-EDTEVEDSIIMDGSVIIGAGRIIESIIGKEVRIVRG 333
           +    E+++S+IM+ + I     + +S+I + V    G
Sbjct: 286 VGAFNEIKESVIMENAKIPHLSYVGDSVICEGVNFGAG 323


>pir||A69079 glucose-1-phosphate thymidylyltransferase homolog -
           Methanobacterium thermoautotrophicum (strain Delta H)
           >gi|2622712|gb|AAB86062.1| (AE000918)
           glucose-1-phosphate thymidylyltransferase homolog
           [Methanobacterium thermoautotrophicum]
           Length = 423
           
 Score =  176 bits (441), Expect = 4e-43
 Identities = 119/341 (34%), Positives = 187/341 (53%), Gaps = 11/341 (3%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           M+A+IL+ G GTR+RPLT ++ K ++PVA KP+L Y+++ + + G+H+I +I G ++E V
Sbjct: 1   MQAVILTAGEGTRMRPLTLTRPKTMLPVAGKPILQYSVDALRDNGVHDIVMITGYHEEAV 60

Query: 61  IETVKSVDWD-ANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHK-E 118
                       NI ++ Q E  G AHAI  A + + +D+F++  GD I   G++     
Sbjct: 61  RSHFGDGSGSGVNITYVRQEERLGTAHAIGQASELI-DDEFIVLNGDIITDPGLMGDLIG 119

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEK--PKHPPSNLALVGIYFFRP 176
            + +   +  ++L EVP+P  FGV ++  +G  ++ +IEK  P     NL   GIY F P
Sbjct: 120 SYHERKPETLMVLREVPDPSSFGVVKV--EGDRVREIIEKPGPDAGAGNLINTGIYVFSP 177

Query: 177 IIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLD 236
            + + +     S R E EITD I   + +   V        W D G+P +LLEA+  ++ 
Sbjct: 178 AVFDYIERTPLSRRGEYEITDTIMMQVRDDLPVRAIISDRDWIDVGRPWELLEASERLMK 237

Query: 237 EIEREIK--VETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVI-RNAYIGPYTSVGN 293
           ++E  ++  VE    I G V I EG  I   T I+GP  IGRN  I  N+Y+  +T +G+
Sbjct: 238 DLEDSVEGDVEDGVTIHGPVAIGEGTIIRSGTYIQGPVYIGRNCDIGPNSYLRAHTCIGD 297

Query: 294 NVVIED-TEVEDSIIMDGSVIIGAGRIIESIIGKEVRIVRG 333
            V I +  EV++SIIMDG+ I     + +S+IG    I  G
Sbjct: 298 GVSIGNAVEVKNSIIMDGTNINHLSYVGDSVIGMNCNIAAG 338


>sp|P39629|SPSI_BACSU SPORE COAT POLYSACCHARIDE BIOSYNTHESIS PROTEIN SPSI
           >gi|2126974|pir||S39726 spore coat polysaccharide
           synthesis spsI - Bacillus subtilis
           >gi|580880|emb|CAA51627.1| (X73124) ipa-71d [Bacillus
           subtilis] >gi|2636319|emb|CAB15810.1| (Z99123) alternate
           gene name: ipa-71d [Bacillus subtilis]
           Length = 246
           
 Score =  159 bits (399), Expect = 4e-38
 Identities = 87/238 (36%), Positives = 140/238 (58%), Gaps = 7/238 (2%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK +IL+GG G+RL PLT +  K L+PV   P+++++I  + EAGI +I +I    KE +
Sbjct: 1   MKGVILAGGNGSRLMPLTKAVNKHLLPVGPYPMIYWSIMKLQEAGIKDILLI--SQKEHM 58

Query: 61  IETVKSVD--WDANIEFIYQGEP--KGLAHAILVARDYLGNDDFVMYLGDNILREGIVRH 116
            +  K +    +  +   YQ +P   G++  +  A+ +   + F++ LGDNI  + +  +
Sbjct: 59  PQFYKLLGNGEELGVTITYQVQPAASGISDGLSYAKRFTKKESFILLLGDNIFEDSLKPY 118

Query: 117 KEHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRP 176
            E FE+    A +LL EV +P++FG+AE+ E  K I+ +IEKP+ PP+NL + GIY +  
Sbjct: 119 TERFEQQGKGAKVLLKEVDDPERFGIAEIDEKNKRIRSIIEKPEQPPTNLCVTGIYMYDA 178

Query: 177 IIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLV 234
            +   +  I PS R ELEITD     I+N  ++ +  ++GWW D G  E L  A++LV
Sbjct: 179 EVFSYIEQISPSKRGELEITDVNNLYIENS-QLTYDVLSGWWVDAGTHESLYLASQLV 235


>gb|AAG18651.1| (AE004970) glucose-1-phosphate thymidylyltransferase; GraD2
           [Halobacterium sp. NRC-1]
           Length = 401
           
 Score =  158 bits (396), Expect = 8e-38
 Identities = 115/344 (33%), Positives = 185/344 (53%), Gaps = 24/344 (6%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           M+A++++ G GTR+ PLT ++ K L+PVA   +L + + D     + E  I+VG   +Q+
Sbjct: 1   MQAIVVAAGRGTRMGPLTETRPKPLVPVAGATLLEHVL-DAAAGVVDEYVIVVGYRGDQI 59

Query: 61  IETVKSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKEHF 120
            E + +      + +  Q   +G AHA+  A  ++     V+  GD  +   +V   E  
Sbjct: 60  RERIGASYAGTPVVYAEQDTQEGTAHAVGCAEPHVEGPCLVLN-GDVYVTSALV---EAL 115

Query: 121 EKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPIIHE 180
             +D  A  ++  V +PQ +GV E  +DG+ +  ++EKP  PP++LA +G+Y F P + E
Sbjct: 116 AGADGTAMSVM-PVADPQSYGVVERGDDGR-VTNVVEKPTDPPTDLANLGLYRFTPRVFE 173

Query: 181 AVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVT--GWWKDTGKPEDLLEANRLVLDEI 238
            +  ++ S R E E+TDA+   ID     G T V+  G W D G+P +LL AN  +L E 
Sbjct: 174 YIDTVERSERGEYELTDALARAIDR-EDGGVTAVSYDGPWLDVGRPWELLAANSALLAEQ 232

Query: 239 EREIK--VETRAKIIGRVKIEEGAKIDENTIIKGPAVI------GRNAVIRNA-YIGPYT 289
           EREI   V   A + GRV +E+GA++ +   I+GP VI      G NA +R A  +GP  
Sbjct: 233 EREINGTVADGATLTGRVVVEDGARVRDGAYIEGPVVIQSGADVGPNAYVRGATVVGPDV 292

Query: 290 SVGNNVVIEDTEVEDSIIMDGSVIIGAGRIIESIIGKEVRIVRG 333
            VGN V     EV++SI+M  + +     + +S++G +V    G
Sbjct: 293 RVGNAV-----EVKNSILMADTAVGHHAYVGDSVLGADVNFGAG 331


>gb|AAG19459.1| (AE005038) glucose-1-phosphate thymidylyltransferase; GraD4
           [Halobacterium sp. NRC-1]
           Length = 240
           
 Score =  155 bits (387), Expect = 9e-37
 Identities = 89/243 (36%), Positives = 139/243 (56%), Gaps = 5/243 (2%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           M+A++L+ G GTRLRPLT  + K ++ +A KP+L +  E ++  G  +I  IVG  K+ +
Sbjct: 1   MQAVVLAAGEGTRLRPLTEDKPKGMVEIAGKPILTHCFEQLVALGAEKIVAIVGYRKQNI 60

Query: 61  IETVKSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKEHF 120
           I           I + +Q E  GLAHA+L A +++ N+DF++ LGDNI R  +       
Sbjct: 61  ISHYGDEFDGVPITYAHQREQNGLAHALLKAEEHV-NEDFMLMLGDNIFRANLEDVVNRQ 119

Query: 121 EKSDYDASILLCEVP--NPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPII 178
           ++   DA+ L+ EV      ++GV + ++ G+ I+ ++EKP  PPSNL + G Y F P I
Sbjct: 120 QEERADAAFLVEEVDWDEASRYGVCDTNDYGE-IQEVVEKPDDPPSNLVMTGFYTFSPAI 178

Query: 179 HEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLDEI 238
            +A + ++PS R E E++DAI  LI +G  +    + GW  D G PED  EA   + D +
Sbjct: 179 FQACKLVQPSDRAEYELSDAIDLLIKSGRTIDAIPMEGWRIDVGYPEDRDEAEERI-DAV 237

Query: 239 ERE 241
             E
Sbjct: 238 SNE 240


>gb|AAG09515.1|AF279619_3 (AF279619) glucose-1-phosphate thymidylyltransferase [Salmonella
           enterica]
           Length = 292
           
 Score =  152 bits (381), Expect = 5e-36
 Identities = 91/257 (35%), Positives = 143/257 (55%), Gaps = 6/257 (2%)

Query: 2   KALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQVI 61
           K +IL+GG GTRL P+T +  KQL+P+ +KP+++Y +  ++ AGI +I II  P      
Sbjct: 5   KGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSMLMLAGIRDILIISTPQDTPRF 64

Query: 62  ETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNIL-REGIVRHKE 118
           E +  +   W  N+++  Q  P GLA A ++  +++GNDD  + LGDNI     + R  E
Sbjct: 65  EQLLGEGSQWGLNLQYKVQPTPDGLAQAFIIGEEFIGNDDCALVLGDNIFYGHDLPRLME 124

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPII 178
                +  A++    V +P+++GV E  +DG  I  L EKP  P SN A+ G+YF+   +
Sbjct: 125 TAVNKESGATVFAYHVNDPERYGVVEFDKDGTAIS-LEEKPLEPKSNYAVTGLYFYDNDV 183

Query: 179 HEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLVLDE 237
            E  +++KPS R ELEITD  +  ++ G         G+ W DTG  + L+EA+  +   
Sbjct: 184 VEMAKNLKPSARGELEITDINRIYMEQGRLSVAMMGRGYAWLDTGTHQSLIEASNFIATI 243

Query: 238 IERE-IKVETRAKIIGR 253
            ER+ +KV    +I  R
Sbjct: 244 EERQGLKVSCPEEIAYR 260


>pir||G69101 mannose-1-phosphate guanyltransferase - Methanobacterium
           thermoautotrophicum (strain Delta H)
           >gi|2622888|gb|AAB86225.1| (AE000931)
           mannose-1-phosphate guanyltransferase [Methanobacterium
           thermoautotrophicum]
           Length = 385
           
 Score =  152 bits (380), Expect = 6e-36
 Identities = 115/355 (32%), Positives = 185/355 (51%), Gaps = 27/355 (7%)

Query: 4   LILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQVIET 63
           ++++GG GTR+RPLT+S+ K L+PVAN+P+L Y I  V+++G  ++ + +G  K+Q+   
Sbjct: 7   VVMAGGKGTRIRPLTFSRPKPLVPVANRPILDYIIHRVLDSGYSKVVMTLGYLKDQIRSH 66

Query: 64  VKSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNI----LREGIVRHKEH 119
           V +   + +  F  + +P G A  +  A   + N+ F++  GD I    LRE +  H+  
Sbjct: 67  VLAEYPEIDFRFSVEKKPLGTAGGVKAAASEI-NETFIVLSGDVIFDLDLREMVKFHR-- 123

Query: 120 FEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPP--SNLALVGIYFFRPI 177
             K +   ++ L  V +P  +G+A L +DGK IKR  EKP+     S +A  GIY   P 
Sbjct: 124 --KKNALVTVALTPVEDPSHYGIAVLDDDGK-IKRFHEKPRPEEVFSKIANAGIYVMEP- 179

Query: 178 IHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLD- 236
             E + HI P   ++    D    LI+    +      G+W D GKP   L AN  VL+ 
Sbjct: 180 --EVIEHI-PQGSSDFS-ADIFPVLIERDAGMYGFLFDGYWNDAGKPNTFLRANHDVLNG 235

Query: 237 ----EIEREIKVETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNA-VIRNAYIGPYTSV 291
               E + EI  E   +  G++ I     I +   I GPAV+G  + V   AYIG  T +
Sbjct: 236 TVTPEPDGEIAEEVPGR-FGKIWIGRDVVIGDRVRIVGPAVLGDGSRVDDGAYIGKNTVI 294

Query: 292 GNNV-VIEDTEVEDSIIMDGSVIIGAGRIIESIIGKEVRIVRGDGHPLGRRLIVG 345
           G+ V V E++ +  S+I+DG VI    +++  ++ ++  I  G G  + R  I+G
Sbjct: 295 GSRVNVGENSFIRGSVILDGCVIGRGSQLLNCVVDEDCEI--GAGCAIDRCAIIG 347


>emb|CAB65204.1| (AJ007311) RmlA protein [Legionella pneumophila]
           Length = 291
           
 Score =  150 bits (376), Expect = 2e-35
 Identities = 92/260 (35%), Positives = 143/260 (54%), Gaps = 6/260 (2%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK +IL+GG+GTRL PLT S  K +IPV +KP+++YAI  ++ A I EI II       +
Sbjct: 1   MKGIILAGGFGTRLYPLTKSISKHMIPVYDKPMIYYAISTLMLANIREILIISTEEHLPL 60

Query: 61  IETVKS--VDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILR-EGIVRHK 117
            + + S    W  +  ++ Q EP+G+A A ++   ++GND   + LGDNI +  G     
Sbjct: 61  YQNLLSDGSQWGISFAYLVQNEPRGIAEAFILGEKFIGNDSVCLVLGDNIHQGRGFSELL 120

Query: 118 EHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPI 177
           ++ +     A++    V  PQ +GV E +E  + +  ++EKP  P SN A+ G+YF+   
Sbjct: 121 QNAKSKLNGATVFAYYVDKPQAYGVVEFNEKQQVLS-IVEKPAQPKSNYAVTGLYFYDNQ 179

Query: 178 IHEAVRHIKPSWRNELEITDAIQ-WLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLD 236
           + E  + +KPS R ELEITD  Q +L +N   V        W D G PE LL A+  +  
Sbjct: 180 VIEIAKSLKPSGRGELEITDINQFYLYENKLDVQILGRGFVWLDMGTPETLLSASNYICT 239

Query: 237 EIERE-IKVETRAKIIGRVK 255
             +R+ +K+    +I  R+K
Sbjct: 240 IEQRQGLKIGCPEEIAWRMK 259


>gb|AAG09500.1|AF279615_3 (AF279615) glucose-1-phosphate thymidylyltransferase [Salmonella
           enterica]
           Length = 292
           
 Score =  150 bits (375), Expect = 2e-35
 Identities = 88/257 (34%), Positives = 141/257 (54%), Gaps = 6/257 (2%)

Query: 2   KALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQVI 61
           K +IL+GG GTRL P+T +  KQL+P+ +KP+++Y +  ++ AGI +I II  P      
Sbjct: 5   KGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPRF 64

Query: 62  ETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNIL-REGIVRHKE 118
           + +      W  N+++  Q  P GLA A ++  +++GNDD  + LGDNI     + +  E
Sbjct: 65  QQLLGDGSQWGLNLQYKVQPSPDGLAQAFIIGEEFIGNDDCALVLGDNIFYGHDLPKLME 124

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPII 178
                +  A++    V +P+++GV E  + G  +  L EKP  P SN A+ G+YF+   +
Sbjct: 125 AAVNKESGATVFAYHVNDPERYGVVEFDQSGTAVS-LEEKPLQPKSNYAVTGLYFYDNSV 183

Query: 179 HEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLVLDE 237
            E  +++KPS R ELEITD  +  +D G         G+ W DTG  + L+EA+  +   
Sbjct: 184 VEMAKNLKPSARGELEITDINRIYMDQGRLSVAMMGRGYAWLDTGTHQSLIEASNFIATI 243

Query: 238 IERE-IKVETRAKIIGR 253
            ER+ +KV    +I  R
Sbjct: 244 EERQGLKVSCPEEIAYR 260


>dbj|BAB07082.1| (AP001518) spore coat polysaccharide synthesis (glucose-1-phosphate
           thymidyltransferase) [Bacillus halodurans]
           Length = 247
           
 Score =  150 bits (374), Expect = 3e-35
 Identities = 80/234 (34%), Positives = 136/234 (57%), Gaps = 7/234 (2%)

Query: 2   KALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQVI 61
           KA+IL+GG G+RL P+T    K L+PV + P+++++I    EAG+HEI I+   ++E + 
Sbjct: 3   KAVILAGGTGSRLSPITRVINKHLLPVGSYPMIYWSILKAKEAGLHEILILT--SREHLA 60

Query: 62  ETVKSV----DWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHK 117
             ++ +    D   ++ +  Q +  G+A A+ +A  ++G++ F++ LGDN+  + +  + 
Sbjct: 61  AFIQLLGDGKDLGVHLHYTIQDQADGIASALSLAEHFVGDEKFLVLLGDNLFADPLTAYV 120

Query: 118 EHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPI 177
           + +EK    A +LL EV +P ++G+A L E  + IK+++EKP    S   + GIY +   
Sbjct: 121 QQYEKQKEGAFVLLKEVRDPTRYGIAFLDETKQKIKKIVEKPNMQGSAYCVTGIYMYDRT 180

Query: 178 IHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEAN 231
           +   +  I PS R ELEITD   + ID G  +G+  +  WW D G  E L +AN
Sbjct: 181 VFSFIEQIAPSARGELEITDVNNFYIDQG-TMGFNILPDWWIDAGTHESLFKAN 233


>gb|AAG09524.1|AF279621_3 (AF279621) glucose-1-phosphate thymidylyltransferase [Salmonella
           enterica]
           Length = 292
           
 Score =  149 bits (372), Expect = 5e-35
 Identities = 87/257 (33%), Positives = 142/257 (54%), Gaps = 6/257 (2%)

Query: 2   KALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQVI 61
           K +IL+GG GTRL P+T +  KQL+P+ +KP+++Y +  ++ AGI +I II  P      
Sbjct: 5   KGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPRF 64

Query: 62  ETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNIL-REGIVRHKE 118
           + +      W  N+++  Q  P GLA A ++  +++GNDD  + LGDNI     + +  +
Sbjct: 65  QQLLGDGSQWGLNLQYKVQPSPDGLAQAFIIGEEFIGNDDCALVLGDNIFYGHDLPKLMD 124

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPII 178
                +  A++    V +P+++GV E  ++G  +  L EKP  P SN A+ G+YF+   +
Sbjct: 125 AAVNKEDGATVFAYHVNDPERYGVVEFDQNGTAVS-LEEKPLQPKSNYAVTGLYFYDNSV 183

Query: 179 HEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLVLDE 237
            E  +++KPS R ELEITD  +  +D G         G+ W DTG  + L+EA+  +   
Sbjct: 184 VEMAKNLKPSARGELEITDINRIYMDQGRLSVAMMGRGYAWLDTGTHQSLIEASNFIATI 243

Query: 238 IERE-IKVETRAKIIGR 253
            ER+ +KV    +I  R
Sbjct: 244 EERQGLKVSCPEEIAYR 260


>sp|P55254|RFBA_SALAN GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (DTDP-GLUCOSE SYNTHASE)
           (DTDP-GLUCOSE PYROPHOSPHORYLASE) >gi|96668|pir||S23342
           glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24)
           [validated] - Salmonella choleraesuis
           >gi|46985|emb|CAA43074.1| (X60665) glucose-1-phosphate
           thymidylyltransferase [Salmonella enterica]
           Length = 292
           
 Score =  148 bits (371), Expect = 7e-35
 Identities = 87/257 (33%), Positives = 141/257 (54%), Gaps = 6/257 (2%)

Query: 2   KALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQVI 61
           K +IL+GG GTRL P+T +  KQL+P+ +KP+++Y +  ++ AGI +I II  P      
Sbjct: 5   KGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPRF 64

Query: 62  ETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNIL-REGIVRHKE 118
           + +      W  N+++  Q  P GLA A ++  +++GNDD  + LGDNI     + +  E
Sbjct: 65  QQLLGDGSQWGLNLQYKVQPSPDGLAQAFIIGEEFIGNDDCALVLGDNIFYGHDLPKLME 124

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPII 178
                +  A++    V +P+++GV E  + G  +  L EKP  P SN A+ G+YF+   +
Sbjct: 125 AAVNKESGATVFAYHVNDPERYGVVEFDQSGTAVS-LEEKPLQPKSNYAVTGLYFYDNSV 183

Query: 179 HEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLVLDE 237
            E  +++KPS R ELEITD  +  ++ G         G+ W DTG  + L+EA+  +   
Sbjct: 184 VEMAKNLKPSARGELEITDINRIYMEQGRLSVAMMGRGYAWLDTGTHQSLIEASNFIATI 243

Query: 238 IERE-IKVETRAKIIGR 253
            ER+ +KV    +I  R
Sbjct: 244 EERQGLKVSCPEEIAYR 260


>gb|AAG09504.1|AF279616_3 (AF279616) glucose-1-phosphate thymidylyltransferase [Salmonella
           enterica]
           Length = 292
           
 Score =  148 bits (371), Expect = 7e-35
 Identities = 87/257 (33%), Positives = 142/257 (54%), Gaps = 6/257 (2%)

Query: 2   KALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQVI 61
           K +IL+GG GTRL P+T +  KQL+P+ +KP+++Y +  ++ AGI +I II  P      
Sbjct: 5   KGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPRF 64

Query: 62  ETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNIL-REGIVRHKE 118
           + +      W  N+++  Q  P GLA A ++  +++G+DD  + LGDNI     + +  E
Sbjct: 65  QQLLGDGSQWGLNLQYKVQPSPDGLAQAFIIGEEFIGHDDCALVLGDNIFYGHDLPKLME 124

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPII 178
                +  A++    V +P+++GV E  ++G  +  L EKP  P SN A+ G+YF+   +
Sbjct: 125 AAVNKESGATVFAYHVNDPERYGVVEFDQNGTAVS-LEEKPLQPKSNYAVTGLYFYDNSV 183

Query: 179 HEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLVLDE 237
            E  +++KPS R ELEITD  +  +D G         G+ W DTG  + L+EA+  +   
Sbjct: 184 VEMAKNLKPSARGELEITDINRIYMDQGRLSVAMMGRGYAWLDTGTHQSLIEASNFIATI 243

Query: 238 IERE-IKVETRAKIIGR 253
            ER+ +KV    +I  R
Sbjct: 244 EERQGLKVSCPEEIAYR 260


>pir||D55213 rfbA protein - Shigella flexneri (strain 2a)
           >gi|294898|gb|AAA53681.1| (L14842) glucose-1-phosphate
           thymidylyltransferase [Shigella flexneri]
           Length = 292
           
 Score =  148 bits (370), Expect = 9e-35
 Identities = 87/257 (33%), Positives = 142/257 (54%), Gaps = 6/257 (2%)

Query: 2   KALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQVI 61
           K +IL+GG GTRL P+T +  KQL+P+ +KP+++Y +  ++ AGI +I II  P      
Sbjct: 5   KGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPRF 64

Query: 62  ETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNIL-REGIVRHKE 118
           + +      W  N+++  Q  P GLA A ++  +++G DD  + LGDNI     + +  +
Sbjct: 65  QQLLGDGSQWGLNLQYKVQPSPDGLAQAFIIGEEFIGGDDCALVLGDNIFYGHDLPKLMD 124

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPII 178
                +  A++    V +P+++GV E  ++G  I  L EKP+ P SN A+ G+YF+   +
Sbjct: 125 TAVNRESGATVFAYHVNDPERYGVVEFDDNGTAIS-LEEKPQEPKSNYAVTGLYFYDNDV 183

Query: 179 HEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLVLDE 237
            E  +++KPS R ELEITD  +  +D G         G+ W DTG  + L+EA+  +   
Sbjct: 184 VEMAKNLKPSARGELEITDINRIYMDQGRLSVAMMGRGYAWLDTGTHQSLIEASNFIATI 243

Query: 238 IERE-IKVETRAKIIGR 253
            ER+ +KV    +I  R
Sbjct: 244 EERQGLKVSCPEEIAHR 260


>gb|AAG09532.1|AF279623_3 (AF279623) glucose-1-phosphate thymidylyltransferase [Salmonella
           enterica]
           Length = 292
           
 Score =  148 bits (369), Expect = 1e-34
 Identities = 87/266 (32%), Positives = 145/266 (53%), Gaps = 6/266 (2%)

Query: 2   KALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQVI 61
           K +IL+GG GTRL P+T +  KQL+P+ +KP+++Y +  ++ AGI +I II  P      
Sbjct: 5   KGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPRF 64

Query: 62  ETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNIL-REGIVRHKE 118
           + +      W  N+++  Q  P GLA A ++  +++GNDD  + LGDNI     + +  +
Sbjct: 65  QQLLGDGSQWGLNLQYKVQPNPDGLAQAFIIGEEFIGNDDCALVLGDNIFYGHDLPKLMD 124

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPII 178
                +  A++    V +P+++GV E  ++G  +  L EKP  P SN A+ G+YF+   +
Sbjct: 125 VAINKENGATVFAYHVNDPERYGVVEFDQNGTAVS-LEEKPLQPKSNYAVTGLYFYDNSV 183

Query: 179 HEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLVLDE 237
            E  +++KPS R ELEITD  +  ++ G         G+ W DTG  + L+EA+  +   
Sbjct: 184 VEMAKNLKPSARGELEITDINRIYMEQGRLSVAMMGRGYAWLDTGTHQSLIEASNFIATI 243

Query: 238 IERE-IKVETRAKIIGRVKIEEGAKI 262
            ER+ +KV    +I  R    +  K+
Sbjct: 244 EERQGLKVSCPEEIAYRKGFIDSQKV 269


>emb|CAC12604.1| (AL445067) mannose-1-phosphate guanyltransferase related protein
           [Thermoplasma acidophilum]
           Length = 359
           
 Score =  147 bits (367), Expect = 2e-34
 Identities = 99/333 (29%), Positives = 174/333 (51%), Gaps = 16/333 (4%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           +K ++++GG GTRLRP+TYS  K L+PVA KPV+ Y ++    +GI +I I  G   E +
Sbjct: 3   LKGVVMAGGKGTRLRPITYSIPKPLVPVAGKPVISYILDAFYRSGISDIIITTGYKFESL 62

Query: 61  IETV-KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKEH 119
           I+ V ++ +   NI F  + E  G A  + +A ++L +D FV+  GD ++   I    + 
Sbjct: 63  IKGVLENKNSQQNILFSVEKEAAGTAGGVKIAENFL-DDTFVVGSGDILIDFDIGDMIKE 121

Query: 120 FEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKP--KHPPSNLALVGIYFFRPI 177
            ++     +I + +V +P QFG+AE+ E+G  IKR +EKP      S+    G+Y    I
Sbjct: 122 HQRRKNKITIAVTKVDDPSQFGIAEIDEEG-YIKRFLEKPGKNETFSDTINAGVY----I 176

Query: 178 IHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLDE 237
           +  ++    PS        D    L+  G K+G   + G W D G+P+D+++AN++++++
Sbjct: 177 MDRSLLRYIPSTGQFDFAKDLFPKLLSQGIKIGTYLIDGVWLDAGRPKDVIKANQIMVEK 236

Query: 238 IEREIKVETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSVGNNVVI 297
                      K I + K+ +G  I     I     +G N+ I  + +    S+G     
Sbjct: 237 YGESF--NGTGKAIIKSKVPQGCSIKPPIYIGEGVHVGNNSTISGSAVYDGVSIG----- 289

Query: 298 EDTEVEDSIIMDGSVIIGAGRIIESIIGKEVRI 330
           +D ++E+S+IM  S I+   +++ S+I +   I
Sbjct: 290 DDVQIENSVIMASSKIMRGTKVVNSVIMQNTTI 322


>sp|P26393|RFBA_SALTY GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (DTDP-GLUCOSE SYNTHASE)
           (DTDP-GLUCOSE PYROPHOSPHORYLASE) >gi|96785|pir||S15301
           glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24)
           - Salmonella typhimurium >gi|47891|emb|CAA40117.1|
           (X56793) glucose-1-phosphate thymidylyltransferase
           [Salmonella enterica]
           Length = 292
           
 Score =  146 bits (365), Expect = 3e-34
 Identities = 86/257 (33%), Positives = 141/257 (54%), Gaps = 6/257 (2%)

Query: 2   KALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQVI 61
           K +IL+GG GTRL P+T +  KQL+P+ +KP+++Y +  ++ AGI +I II  P      
Sbjct: 5   KGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPRF 64

Query: 62  ETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNIL-REGIVRHKE 118
           + +      W  N+++  Q  P GLA A ++  +++G+DD  + LGDNI     + +  E
Sbjct: 65  QQLLGDGSQWGLNLQYKVQPSPDGLAQAFIIGEEFIGHDDCALVLGDNIFYGHDLPKLME 124

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPII 178
                +  A++    V +P+++GV E  + G  +  L EKP  P SN A+ G+YF+   +
Sbjct: 125 AAVNKESGATVFAYHVNDPERYGVVEFDQKGTAVS-LEEKPLQPKSNYAVTGLYFYDNSV 183

Query: 179 HEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLVLDE 237
            E  +++KPS R ELEITD  +  ++ G         G+ W DTG  + L+EA+  +   
Sbjct: 184 VEMAKNLKPSARGELEITDINRIYMEQGRLSVAMMGRGYAWLDTGTHQSLIEASNFIATI 243

Query: 238 IERE-IKVETRAKIIGR 253
            ER+ +KV    +I  R
Sbjct: 244 EERQGLKVSCPEEIAFR 260


>sp|P37744|RBA1_ECOLI GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (DTDP-GLUCOSE SYNTHASE)
           (DTDP-GLUCOSE PYROPHOSPHORYLASE) >gi|7434865|pir||F64969
           glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24)
           - Escherichia coli (strain K-12)
           >gi|1736729|dbj|BAA15881.1| (D90841) Glucose-1-phosphate
           thymidylyltransferase (EC 2.7.7.24) (dTDP-glucose
           synthase) (dTDP-glucose pyrophosphorylase). [Escherichia
           coli] >gi|1736742|dbj|BAA15893.1| (D90842)
           Glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24)
           (dTDP-glucose synthase) (dTDP-glucose
           pyrophosphorylase). [Escherichia coli]
           >gi|1788351|gb|AAC75100.1| (AE000294)
           glucose-1-phosphate thymidylyltransferase [Escherichia
           coli K12] >gi|2665491|gb|AAB88400.1| (U09876)
           glucose-1-phosphate thymidylyltransferase [Escherichia
           coli]
           Length = 293
           
 Score =  146 bits (365), Expect = 3e-34
 Identities = 88/269 (32%), Positives = 147/269 (53%), Gaps = 9/269 (3%)

Query: 2   KALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQVI 61
           K +IL+GG GTRL P+T +  KQL+P+ +KP+++Y +  ++ AGI +I II  P      
Sbjct: 5   KGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPRF 64

Query: 62  ETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNIL-REGIVRHKE 118
           + +      W  N+++  Q  P GLA A ++  +++G DD  + LGDNI     + +  E
Sbjct: 65  QQLLGDGSQWGLNLQYKVQPSPDGLAQAFIIGEEFIGGDDCALVLGDNIFYGHDLPKLME 124

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPII 178
                +  A++    V +P+++GV E  ++G  I  L EKP  P SN A+ G+YF+   +
Sbjct: 125 AAVNKESGATVFAYHVNDPERYGVVEFDKNGTAIS-LEEKPLEPKSNYAVTGLYFYDNDV 183

Query: 179 HEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLVLDE 237
            +  +++KPS R ELEITD  +  ++ G         G+ W DTG  + L+EA+  +   
Sbjct: 184 VQMAKNLKPSARGELEITDINRIYLEQGRLSVAMMGRGYAWLDTGTHQSLIEASNFIATI 243

Query: 238 IERE-IKVETRAKII---GRVKIEEGAKI 262
            ER+ +KV    +I    G + +E+  K+
Sbjct: 244 EERQGLKVSCPEEIAFRKGFIDVEQVRKL 272


>pir||I69650 glucose-1-phosphate thymidylyltransferase - Escherichia coli
           Length = 293
           
 Score =  146 bits (365), Expect = 3e-34
 Identities = 88/269 (32%), Positives = 147/269 (53%), Gaps = 9/269 (3%)

Query: 2   KALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQVI 61
           K +IL+GG GTRL P+T +  KQL+P+ +KP+++Y +  ++ AGI +I II  P      
Sbjct: 5   KGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPRF 64

Query: 62  ETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNIL-REGIVRHKE 118
           + +      W  N+++  Q  P GLA A ++  +++G DD  + LGDNI     + +  E
Sbjct: 65  QQLLGDGSQWGLNLQYKVQPSPDGLAQAFIIGEEFIGGDDCALVLGDNIFYGHDLPKLME 124

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPII 178
                +  A++    V +P+++GV E  ++G  I  L EKP  P SN A+ G+YF+   +
Sbjct: 125 AAVNKESGATVFAYHVNDPERYGVVEFDKNGTAIS-LEEKPLEPKSNYAVTGLYFYDNDV 183

Query: 179 HEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLVLDE 237
            +  +++KPS R ELEITD  +  ++ G         G+ W DTG  + L+EA+  +   
Sbjct: 184 VQMAKNLKPSARGELEITDINRIYLEQGRLSVAMMGRGYAWLDTGTHQSLIEASNFIATI 243

Query: 238 IERE-IKVETRAKII---GRVKIEEGAKI 262
            ER+ +KV    +I    G + +E+  K+
Sbjct: 244 EERQGLKVSCPEEIAFRKGFIDVEQVRKL 272


>gb|AAG09536.1|AF279624_3 (AF279624) glucose-1-phosphate thymidylyltransferase [Salmonella
           enterica]
           Length = 289
           
 Score =  146 bits (365), Expect = 3e-34
 Identities = 90/273 (32%), Positives = 148/273 (53%), Gaps = 7/273 (2%)

Query: 2   KALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQVI 61
           K +IL+GG GTRL P+T +  KQL+P+ +KP+++Y +  ++ AGI +I II  P      
Sbjct: 5   KGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPRF 64

Query: 62  ETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNIL-REGIVRHKE 118
           + +      W  N+++  Q  P GLA A ++  +++GNDD  + LGDNI     + +  +
Sbjct: 65  QQLLGDGSQWGLNLQYKVQLSPDGLAQAFIIGEEFIGNDDCALVLGDNIFYGHDLPKLMD 124

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPII 178
                +  A++    V +P+++GV E  ++G  +  L EKP  P SN A+ G+YF+   +
Sbjct: 125 AAVNKEDGATVFAYHVNDPERYGVVEFDKNGTAVS-LEEKPLQPKSNYAVTGLYFYDNSV 183

Query: 179 HEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLVLDE 237
               +++KPS R ELEITD  +  ++ G         G+ W DTG  + L+EA+  +   
Sbjct: 184 VAMAKNLKPSARGELEITDINRIYMEQGRLSVAMMGRGYAWLDTGTHQSLIEASNFIATI 243

Query: 238 IERE-IKVETRAKIIGRVKIEEGAKIDENTIIK 269
            ER+ +KV    +I  R       KI +N I+K
Sbjct: 244 EERQGLKVACLEEIAYRKNYISKEKI-QNAILK 275


>gb|AAD10181.1| (AF026471) Cps2L [Streptococcus pneumoniae]
           Length = 289
           
 Score =  146 bits (364), Expect = 5e-34
 Identities = 88/241 (36%), Positives = 137/241 (56%), Gaps = 11/241 (4%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPN---- 56
           MK +IL+GG GTRL PLT +  KQL+PV +KP+++Y +  ++ AGI +I II  P     
Sbjct: 1   MKGIILAGGSGTRLYPLTRATSKQLMPVYDKPMIYYPLSTLMLAGIKDILIISTPQDLPR 60

Query: 57  -KEQVIETVKSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILR-EGIV 114
            K+ +++     ++   + +  Q  P GLA A L+  D++G+D   + LGDNI    G+ 
Sbjct: 61  FKDLLLD---GSEFGIRLSYAEQPSPDGLAQAFLIGEDFIGDDSVALILGDNIYHGPGLS 117

Query: 115 RHKEHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFF 174
           +  +     +  A++   +V +P++FGV E  E+   I  + EKP+ P SN A+ G+YF+
Sbjct: 118 KMLQKTVSKEKGATVFGYQVKDPERFGVVEFDENMNAIS-IEEKPECPRSNYAVTGLYFY 176

Query: 175 RPIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRL 233
              + E  + IKPS R ELEITD  +  +D G         G+ W DTG  E LLEA++ 
Sbjct: 177 DNDVVEIAKSIKPSARGELEITDVNKAYLDRGNLSVEVMGRGFAWLDTGTHESLLEASQY 236

Query: 234 V 234
           +
Sbjct: 237 I 237


>pir||D83000 glucose-1-phosphate thymidylyltransferase PA5163 [imported] -
           Pseudomonas aeruginosa (strain PAO1)
           >gi|9951465|gb|AAG08548.1|AE004929_3 (AE004929)
           glucose-1-phosphate thymidylyltransferase [Pseudomonas
           aeruginosa]
           Length = 293
           
 Score =  146 bits (364), Expect = 5e-34
 Identities = 93/272 (34%), Positives = 144/272 (52%), Gaps = 14/272 (5%)

Query: 2   KALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQVI 61
           K +IL+GG GTRL P T +  KQL+PV +KP+++Y +  ++ AGI EI II  P      
Sbjct: 4   KGIILAGGSGTRLHPATLAISKQLLPVYDKPMIYYPLSTLMLAGIREILIISTPQDTPRF 63

Query: 62  ETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKEH 119
           + +     +W  ++++  Q  P GLA A L+   ++GND   + LGDN+       H  H
Sbjct: 64  QQLLGDGSNWGLDLQYAVQPSPDGLAQAFLIGESFIGNDLSALVLGDNL----YYGHDFH 119

Query: 120 -----FEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFF 174
                  +    AS+    V +P+++GV E  + GK I  L EKP  P SN A+ G+YF+
Sbjct: 120 ELLGSASQRQTGASVFAYHVLDPERYGVVEFDQGGKAIS-LEEKPLEPKSNYAVTGLYFY 178

Query: 175 RPIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRL 233
              + +  R +KPS R ELEITD  +  ++ G         G+ W DTG  + LLEA + 
Sbjct: 179 DQQVVDIARDLKPSPRGELEITDVNRAYLERGQLSVEIMGRGYAWLDTGTHDSLLEAGQF 238

Query: 234 VLD-EIEREIKVETRAKIIGRVKIEEGAKIDE 264
           +   E  + +KV    +I  R K  + A++++
Sbjct: 239 IATLENRQGLKVACPEEIAYRQKWIDAAQLEK 270


>sp|P55253|RBA2_ECOLI GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (DTDP-GLUCOSE SYNTHASE)
           (DTDP-GLUCOSE PYROPHOSPHORYLASE) >gi|7434862|pir||S78544
           glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24)
           - Escherichia coli (strain VW187 )
           >gi|799234|gb|AAC63614.1| (AF125322) RmlA [Escherichia
           coli]
           Length = 293
           
 Score =  145 bits (363), Expect = 6e-34
 Identities = 88/258 (34%), Positives = 141/258 (54%), Gaps = 7/258 (2%)

Query: 2   KALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQVI 61
           K +IL+GG GTRL P+T +  KQL+P+ +KP+++Y +  ++ AGI +I II  P      
Sbjct: 5   KGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPRF 64

Query: 62  ETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNIL-REGIVRHKE 118
           + +      W  N+++  Q  P GLA A ++  D++G DD  + LGDNI     + +  E
Sbjct: 65  QQLLGDGSQWGLNLQYKVQPSPDGLAQAFIIGEDFIGGDDCALVLGDNIFYGHDLPKLME 124

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFF-RPI 177
                +  A++    V +P+++GV E   +G  I  L EKP  P SN A+ G+YF+   +
Sbjct: 125 AAVNKESGATVFAYHVNDPERYGVVEFDNNGTAIS-LEEKPLEPKSNYAVTGLYFYDNDV 183

Query: 178 IHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLVLD 236
           +  A +++KPS R ELEITD  +  ++ G         G+ W DTG  + L+EA+  +  
Sbjct: 184 VEMARKNLKPSARGELEITDINRIYMEQGRLSVAMMGRGYAWLDTGTHQSLIEASNFIAT 243

Query: 237 EIERE-IKVETRAKIIGR 253
             ER+ +KV    +I  R
Sbjct: 244 IEERQGLKVSCPEEIAYR 261


>sp|P95778|RMLA_STRMU GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (DTDP-GLUCOSE SYNTHASE)
           (DTDP-GLUCOSE PYROPHOSPHORYLASE)
           >gi|1813345|dbj|BAA11247.1| (D78182) glucose-1-phosphate
           thymidyltransferase [Streptococcus mutans]
           Length = 289
           
 Score =  145 bits (363), Expect = 6e-34
 Identities = 87/238 (36%), Positives = 134/238 (55%), Gaps = 5/238 (2%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK +IL+GG GTRL PLT +  KQL+PV +KP+++Y +  ++ AGI +I II  P     
Sbjct: 1   MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLAGIKDILIISTPQDLPR 60

Query: 61  IETVKSVDWDANIEFIY--QGEPKGLAHAILVARDYLGNDDFVMYLGDNI-LREGIVRHK 117
            + +     +  I+  Y  Q  P GLA A ++  +++G+D   + LGDNI    G+ R  
Sbjct: 61  FKELLQDGSEFGIKLSYAEQPSPDGLAQAFIIGEEFIGDDHVALILGDNIYYGPGLSRML 120

Query: 118 EHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPI 177
           +     +  A++   +V +P++FGV E   D   I  + EKP+HP S+ A+ G+YF+   
Sbjct: 121 QKAASKESGATVFGYQVKDPERFGVVEFDNDRNAIS-IEEKPEHPKSHYAVTGLYFYDNS 179

Query: 178 IHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLV 234
           + +  ++IKPS R ELEITD  +  +D G         G+ W DTG  E LLEA + +
Sbjct: 180 VVDIAKNIKPSPRGELEITDVNKAYLDRGDLSVEVMERGFAWLDTGTHESLLEAAQYI 237


>gb|AAC35920.1| (AF071085) putative glucose-1-phosphate thymidyl transferase
           [Enterococcus faecalis]
           Length = 288
           
 Score =  145 bits (363), Expect = 6e-34
 Identities = 88/238 (36%), Positives = 134/238 (55%), Gaps = 5/238 (2%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK +IL+GG GTRL PLT +  KQL+P+ +KP+++Y +  ++ AGI+EI II  P     
Sbjct: 1   MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLAGINEILIISTPEDTPR 60

Query: 61  IETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNI-LREGIVRHK 117
            E++     D   +IE+  Q  P GLA A ++  +++G+D   + LGDNI    G+ +  
Sbjct: 61  FESLFGDGHDLGIHIEYAVQESPDGLAQAFIIGEEFIGDDSVCLVLGDNIYYGGGLSKML 120

Query: 118 EHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPI 177
           +     +  A++    V +P++FGV E  E+ + +  + EKP  P SN A+ G+YF+   
Sbjct: 121 QRAASKESGATVFGYHVNDPERFGVVEFDEEMRALS-IEEKPAQPKSNYAVTGLYFYDNE 179

Query: 178 IHEAVRHIKPSWRNELEITDAIQ-WLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLV 234
           + E  + IKPS R ELEITD  + +L  N   V        W DTG  E LLEA+  +
Sbjct: 180 VVEIAKGIKPSERGELEITDVNKVYLEKNKLSVEVMGRGFAWLDTGTHESLLEASTFI 237


>gb|AAC38757.1| (AF030373) glucose-1-phosphate thymidyl transferase [Streptococcus
           pneumoniae] >gi|3818496|gb|AAC69538.1| (AF057294)
           Cps23fO [Streptococcus pneumoniae]
           Length = 289
           
 Score =  145 bits (362), Expect = 8e-34
 Identities = 88/238 (36%), Positives = 134/238 (55%), Gaps = 5/238 (2%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK +IL+GG GTRL PLT +  KQL+PV +KP+++Y +  ++ AGI +I II  P     
Sbjct: 1   MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLAGIRDILIISTPQDLPR 60

Query: 61  IETVKSVDWDANIEFIY--QGEPKGLAHAILVARDYLGNDDFVMYLGDNILR-EGIVRHK 117
            + +     +  I+  Y  Q  P GLA A ++  +++G+D   + LGDNI    G+    
Sbjct: 61  FKELLQDGSEFGIKLSYAEQPSPDGLAQAFIIGEEFIGDDSVALILGDNIYHGPGLSTML 120

Query: 118 EHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPI 177
           +   K +  A++    V +P++FGV E  E+   I  + EKP++P SN A+ G+YF+   
Sbjct: 121 QKAAKKEKGATVFGYHVKDPERFGVVEFDENMNAIS-IEEKPEYPRSNYAVTGLYFYDND 179

Query: 178 IHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLV 234
           + E  + IKPS R ELEITD  +  +D G         G+ W DTG  E LLEA++ +
Sbjct: 180 VVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRGFAWLDTGTHESLLEASQYI 237


>gb|AAC44969.1| (U09239) glucose-1-phosphate thymidyl transferase [Streptococcus
           pneumoniae]
           Length = 289
           
 Score =  145 bits (361), Expect = 1e-33
 Identities = 85/238 (35%), Positives = 133/238 (55%), Gaps = 5/238 (2%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK +IL+GG GTRL PLT +  KQL+PV +KP+++Y +  ++ AGI +I II  P     
Sbjct: 1   MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLAGIRDILIISTPQDLHR 60

Query: 61  IETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILR-EGIVRHK 117
            + +     ++   + +  Q  P GLA A ++  +++ +D   + LGDNI    G+ +  
Sbjct: 61  FQELLQDGSEFGLKLSYAEQPSPDGLAQAFIIGEEFISDDSVALILGDNIYHGSGLSKML 120

Query: 118 EHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPI 177
           +     +  A++    V +P++FGV E  +D K I  + EKP+ P SN A+ G+YF+   
Sbjct: 121 QKAASKESGATVFGYHVKDPERFGVVEFDQDMKAIS-IEEKPEQPRSNYAVTGLYFYDND 179

Query: 178 IHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLV 234
           + E  + IKPS R ELEITD  +  +D G         G+ W DTG  E LLEA++ +
Sbjct: 180 VVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRGFAWLDTGTHESLLEASQYI 237


>gb|AAC78674.1| (AF094575) glucose-1-phosphate thimidylyl transferase Cps19aL
           [Streptococcus pneumoniae]
           Length = 289
           
 Score =  145 bits (361), Expect = 1e-33
 Identities = 87/241 (36%), Positives = 137/241 (56%), Gaps = 11/241 (4%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPN---- 56
           MK +IL+GG GTRL PLT +  KQL+PV +KP+++Y +  ++ AGI +I II  P     
Sbjct: 1   MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLAGIKDILIISTPQDLPR 60

Query: 57  -KEQVIETVKSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILR-EGIV 114
            K+ +++     ++   + +  Q  P GLA A L+  +++G+D   + LGDNI    G+ 
Sbjct: 61  FKDLLLD---GSEFGIKLSYAEQPSPDGLAQAFLIGEEFIGDDSVALILGDNIYHGPGLS 117

Query: 115 RHKEHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFF 174
              +   K +  A++   +V +P++FGV E   D   I  + EKP++P SN A+ G+YF+
Sbjct: 118 TMLQKAAKKEKGATVFGYQVKDPERFGVVEFDTDMNAIS-IEEKPEYPRSNYAVTGLYFY 176

Query: 175 RPIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRL 233
              + E  + IKPS R ELEITD  +  ++ G         G+ W DTG  E LLEA++ 
Sbjct: 177 DNDVVEIAKQIKPSARGELEITDVNKAYLNRGDLSVELMGRGFAWLDTGTHESLLEASQY 236

Query: 234 V 234
           +
Sbjct: 237 I 237


>gb|AAD19913.1| (AF105113) glucose-1-phosphate thymidylyl transferase
           [Streptococcus pneumoniae]
           Length = 289
           
 Score =  145 bits (361), Expect = 1e-33
 Identities = 87/241 (36%), Positives = 137/241 (56%), Gaps = 11/241 (4%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPN---- 56
           MK +IL+GG GTRL PLT +  KQL+PV +KP+++Y +  ++ AGI +I II  P     
Sbjct: 1   MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLAGIKDILIISTPQDLPR 60

Query: 57  -KEQVIETVKSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILR-EGIV 114
            K+ +++     ++   + +  Q  P GLA A L+  +++G+D   + LGDNI    G+ 
Sbjct: 61  FKDLLLD---GSEFGIKLSYAEQPSPDGLAQAFLIGEEFIGDDSVALILGDNIYHGPGLS 117

Query: 115 RHKEHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFF 174
              +   K +  A++   +V +P++FGV E   D   I  + EKP++P SN A+ G+YF+
Sbjct: 118 TMLQKAAKKEKGATVFGYQVKDPERFGVVEFDTDMNAIS-IEEKPEYPRSNYAVTGLYFY 176

Query: 175 RPIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRL 233
              + E  + IKPS R ELEITD  +  ++ G         G+ W DTG  E LLEA++ 
Sbjct: 177 DNDVVEIAKQIKPSARGELEITDVNKAYLNRGDLSVELMGRGFAWLDTGTHESLLEASQY 236

Query: 234 V 234
           +
Sbjct: 237 I 237


>gb|AAG09519.1|AF279620_3 (AF279620) glucose-1-phosphate thymidylyltransferase [Salmonella
           enterica]
           Length = 290
           
 Score =  145 bits (361), Expect = 1e-33
 Identities = 81/244 (33%), Positives = 135/244 (55%), Gaps = 5/244 (2%)

Query: 2   KALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQVI 61
           K +IL+GG GTRL P+T +  KQL+P+ +KP+++Y +  ++ AGI +I II  P      
Sbjct: 5   KGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPRF 64

Query: 62  ETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNIL-REGIVRHKE 118
           + +      W  N+++  Q  P GLA A ++  +++GNDD  + LGDNI     + +  +
Sbjct: 65  QQLLGDGSQWGLNLQYKVQPNPDGLAQAFIIGEEFIGNDDCALVLGDNIFYGHDLPKLMD 124

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPII 178
                +  A++    V +P+++GV E  ++G  +  L EKP  P SN A+ G+YF+   +
Sbjct: 125 VAVNKENGATVFAYHVNDPERYGVVEFDQNGTAVS-LEEKPLQPKSNYAVTGLYFYDNSV 183

Query: 179 HEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLVLDE 237
               +++KPS R ELEITD  +  ++ G         G+ W DTG  + L+EA+  +   
Sbjct: 184 VAMAKNLKPSARGELEITDINRIYMEQGRLSVAMMGRGYAWLDTGTHQSLIEASNFIATI 243

Query: 238 IERE 241
            ER+
Sbjct: 244 EERQ 247


>gb|AAG09539.1|AF279625_3 (AF279625) glucose-1-phosphate thymidylyltransferase [Salmonella
           enterica]
           Length = 292
           
 Score =  145 bits (361), Expect = 1e-33
 Identities = 85/257 (33%), Positives = 141/257 (54%), Gaps = 6/257 (2%)

Query: 2   KALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQVI 61
           K +IL+GG GT L P+T +  KQL+P+ +KP+++Y +  ++ AGI +I II  P      
Sbjct: 5   KGIILAGGSGTSLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPRF 64

Query: 62  ETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNIL-REGIVRHKE 118
           + +      W  N+++  Q  P GLA A ++  +++G+DD  + LGDNI     + +  E
Sbjct: 65  QQLLGDGSQWGLNLQYKVQPSPDGLAQAFIIGEEFIGHDDCALVLGDNIFYGHDLPKLME 124

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPII 178
                +  A++    V +P+++GV E  ++G  +  L EKP  P SN A+ G+YF+   +
Sbjct: 125 AAVNKESGATVFAYHVNDPERYGVVEFDQNGTAVS-LEEKPLQPKSNYAVTGLYFYDNSV 183

Query: 179 HEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLVLDE 237
            E  +++KPS R ELEITD  +  ++ G         G+ W DTG  + L+EA+  +   
Sbjct: 184 VEMAKNLKPSARGELEITDINRIYMEQGRLSVAMMGRGYAWLDTGTHQSLIEASNFIATI 243

Query: 238 IERE-IKVETRAKIIGR 253
            ER+ +KV    +I  R
Sbjct: 244 EERQGLKVSCPEEIAYR 260


>pir||S78498 probable glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) -
           Neisseria meningitidis >gi|388934|gb|AAA63158.1|
           (L09188) TDP-deoxyglucose-epimerase [Neisseria
           meningitidis]
           Length = 328
           
 Score =  144 bits (360), Expect = 1e-33
 Identities = 83/238 (34%), Positives = 133/238 (55%), Gaps = 5/238 (2%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK +IL+GG GTRL P+T    KQL+PV +KP+++Y +  ++ AGI +I +I  P     
Sbjct: 41  MKGIILAGGSGTRLYPITRGVSKQLLPVYDKPMIYYPLSVLMLAGIRDILVITAPEDNAS 100

Query: 61  IETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNIL-REGIVRHK 117
            + +     D   +I +  Q  P GLA A ++  +++GND+  + LGDNI   +   +  
Sbjct: 101 FKRLLGDGSDLGISISYAVQPSPDGLAQAFIIGEEFIGNDNVCLVLGDNIFYGQSFTQTL 160

Query: 118 EHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPI 177
           +   +  + A++   +V NP++FGV E +E+ + +  + EKP+ P S+ A+ G+YF+   
Sbjct: 161 KQAARQTHGATVFAYQVKNPERFGVVEFNENFRAVS-IEEKPQRPKSDWAVTGLYFYDNR 219

Query: 178 IHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLV 234
             E  + IKPS R ELEITD  +  +++G         G+ W DTG  E L EA   V
Sbjct: 220 AVEFAKQIKPSARGELEITDLNRMYLEDGSLSVQILGRGFAWLDTGTHESLHEAASFV 277


>gb|AAG09528.1|AF279622_3 (AF279622) glucose-1-phosphate thymidylyltransferase [Salmonella
           enterica]
           Length = 292
           
 Score =  144 bits (360), Expect = 1e-33
 Identities = 85/257 (33%), Positives = 140/257 (54%), Gaps = 6/257 (2%)

Query: 2   KALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQVI 61
           K +IL+GG GTRL P+T +  KQL+P+ +KP+++Y +  ++ AGI +I II  P      
Sbjct: 5   KGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPRF 64

Query: 62  ETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNIL-REGIVRHKE 118
           + +      W  N+++  Q  P GLA A ++  +++GNDD  + LGDNI     + +  +
Sbjct: 65  QQLLGDGSQWGLNLQYKVQPSPDGLAQAFIIGEEFIGNDDCALVLGDNIFYGHDLPKLMD 124

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPII 178
                +  A++    V +P+++GV E  ++G  +  L EKP  P SN A+ G+YF+   +
Sbjct: 125 AAVNKEDGATVFAYHVNDPERYGVVEFDQNGTAVS-LEEKPLQPKSNYAVTGLYFYDNSV 183

Query: 179 HEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLVLDE 237
               + +KPS R ELEITD  +  ++ G         G+ W DTG  + L+EA+  +   
Sbjct: 184 VAMAKKLKPSARGELEITDINRIYMEQGRLSVAMMGRGYAWLDTGTHQSLIEASNFIATI 243

Query: 238 IERE-IKVETRAKIIGR 253
            ER+ +KV    +I  R
Sbjct: 244 EERQGLKVSCPEEIAYR 260


>sp|P55256|RFBA_XANCA GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (DTDP-GLUCOSE SYNTHASE)
           (DTDP-GLUCOSE PYROPHOSPHORYLASE) >gi|1073091|pir||A49906
           glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24)
           - Xanthomonas campestris pv. campestris
           >gi|398119|gb|AAA16191.1| (L23941) TDP-glucose
           pyrophosphorylase [Xanthomonas campestris]
           Length = 295
           
 Score =  144 bits (359), Expect = 2e-33
 Identities = 85/237 (35%), Positives = 132/237 (54%), Gaps = 5/237 (2%)

Query: 2   KALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQVI 61
           K +IL+GG GTRL P+T    KQL+PV +KP+++Y +  ++ AGI +I II  P+++ + 
Sbjct: 5   KGIILAGGSGTRLYPITKGVSKQLLPVYDKPMIYYPLSVLMLAGIRDILIINTPHEQALF 64

Query: 62  ETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILR-EGIVRHKE 118
           +++      W  NI++  Q  P GLA A L+ RD++G     + LGDNI    G+     
Sbjct: 65  QSLLGDGAQWGVNIQYAVQPSPDGLAQAYLIGRDFVGGKPSCLVLGDNIFHGHGLTDTLR 124

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPII 178
             +  +  A++    V +P+++GVAE  + GK I  + EKP+ P SN A+ G+YF+    
Sbjct: 125 RADAREQGATVFGYWVNDPERYGVAEFDQHGKVID-IAEKPEKPRSNYAVTGLYFYDGKA 183

Query: 179 HEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLV 234
            +    +KPS R ELEITD  +  +D G         G+ W DTG  + L EA   +
Sbjct: 184 SDYAAALKPSPRGELEITDLNRCYLDAGDLHLEPLGRGYAWLDTGTHQSLHEAANFI 240


>gb|AAD31799.1|AF128273_2 (AF128273) TDP-glucose synthase homolog [Streptomyces griseus]
           Length = 289
           
 Score =  144 bits (359), Expect = 2e-33
 Identities = 85/238 (35%), Positives = 135/238 (56%), Gaps = 5/238 (2%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK +IL+GG+GTRL+P+T+   KQL+PV +KP+++Y +  ++ AGI +I I+  P+  Q 
Sbjct: 1   MKGIILAGGHGTRLQPITFGVSKQLLPVYDKPMIYYPLSVLMLAGITDIQIVAAPDGLQG 60

Query: 61  IETVKSVDWDANIEFIY--QGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKE 118
              +     D  ++  Y  Q +P+GLA A LV+ D++G+D   + LGDN+          
Sbjct: 61  FRRLLGDGSDLGLDLSYAEQDKPRGLADAFLVSEDHIGDDAVALVLGDNLFHGPGFSDIL 120

Query: 119 HFEKSDYDASILL-CEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPI 177
                D D ++L    V +P+++GV E+   G  +  L EKP  P SNLA+ G+YF+   
Sbjct: 121 RRVALDLDGAVLFGYPVRDPERYGVGEVDGAG-NLTALEEKPARPRSNLAITGLYFYDND 179

Query: 178 IHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLV 234
           + E  R ++PS R ELEITD  +  ++ G         G+ W DTG  + L++A + V
Sbjct: 180 VVEIARSLRPSERGELEITDVNRRYLERGKAALVQLGRGFVWLDTGTHDALIDAGQYV 237


>gb|AAG09508.1|AF279617_3 (AF279617) glucose-1-phosphate thymidylyltransferase [Salmonella
           enterica]
           Length = 289
           
 Score =  144 bits (359), Expect = 2e-33
 Identities = 89/273 (32%), Positives = 147/273 (53%), Gaps = 7/273 (2%)

Query: 2   KALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQVI 61
           K +IL+GG GTRL P+T +  KQL+P+ +KP+++Y +  ++ AGI +I II  P      
Sbjct: 5   KGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPRF 64

Query: 62  ETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNIL-REGIVRHKE 118
           + +      W  N+++  Q  P GLA A ++  +++GND+  + LGDNI     + +   
Sbjct: 65  QQLLGDGSQWGLNLQYKVQLSPDGLAQAFIIGEEFIGNDNCALVLGDNIFYGHDLPKLMN 124

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPII 178
                +  A++    V +P+++GV E  ++G  +  L EKP  P SN A+ G+YF+   +
Sbjct: 125 AAVNKEDGATVFAYHVNDPERYGVVEFDQNGTAVS-LEEKPLQPKSNYAVTGLYFYDNSV 183

Query: 179 HEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLVLDE 237
               +++KPS R ELEITD  +  ++ G         G+ W DTG  + L+EA+  +   
Sbjct: 184 VAMAKNLKPSARGELEITDINRIYMEQGRLSVAMMGRGYAWLDTGTHQSLIEASNFIATI 243

Query: 238 IERE-IKVETRAKIIGRVKIEEGAKIDENTIIK 269
            ER+ +KV    +I  R       KI +N I+K
Sbjct: 244 EERQGLKVACLEEIAYRKNYISKEKI-QNAILK 275


>sp|P55255|RFBA_NEIMB GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (DTDP-GLUCOSE SYNTHASE)
           (DTDP-GLUCOSE PYROPHOSPHORYLASE)
           >gi|11261719|pir||B81240 glucose-1-phosphate
           thymidylyltransferase NMB0080, NMB0062 [imported] -
           Neisseria meningitidis (group B strain MD58)
           >gi|7225282|gb|AAF40530.1| (AE002365)
           glucose-1-phosphate thymidylyltransferase [Neisseria
           meningitidis MC58] >gi|7225298|gb|AAF40544.1| (AE002367)
           glucose-1-phosphate thymidylyltransferase [Neisseria
           meningitidis MC58]
           Length = 288
           
 Score =  143 bits (358), Expect = 2e-33
 Identities = 82/238 (34%), Positives = 133/238 (55%), Gaps = 5/238 (2%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK +IL+GG GTRL P+T    KQL+PV +KP+++Y +  ++ AGI +I +I  P     
Sbjct: 1   MKGIILAGGSGTRLYPITRGVSKQLLPVYDKPMIYYPLSVLMLAGIRDILVITAPEDNAS 60

Query: 61  IETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNIL-REGIVRHK 117
            + +     D+  +I +  Q  P GLA A ++  +++GND+  + LGDNI   +   +  
Sbjct: 61  FKRLLGDGSDFGISISYAVQPSPDGLAQAFIIGEEFIGNDNVCLVLGDNIFYGQSFTQTL 120

Query: 118 EHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPI 177
           +      + A++   +V NP++FGV E +E+ + +  + EKP+ P S+ A+ G+YF+   
Sbjct: 121 KQAAAQTHGATVFAYQVKNPERFGVVEFNENFRAVS-IEEKPQRPKSDWAVTGLYFYDNR 179

Query: 178 IHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLV 234
             E  + +KPS R ELEITD  +  +++G         G+ W DTG  E L EA   V
Sbjct: 180 AVEFAKQLKPSARGELEITDLNRMYLEDGSLSVQILGRGFAWLDTGTHESLHEAASFV 237


>gb|AAC37050.1| (L09189) glucose-1-phosphate thymidyl transferase [Neisseria
           meningitidis]
           Length = 301
           
 Score =  143 bits (357), Expect = 3e-33
 Identities = 81/238 (34%), Positives = 134/238 (56%), Gaps = 5/238 (2%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK +IL+GG GTRL P+T    KQL+PV +KP+++Y +  ++ AGI +I +I  P     
Sbjct: 14  MKGIILAGGSGTRLYPITRGVSKQLLPVYDKPMIYYPLSVLMLAGIRDILVITAPEDNAS 73

Query: 61  IETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNIL-REGIVRHK 117
            + +     D+  +I +  Q  P GLA A ++  +++GND+  + LGDNI   +   +  
Sbjct: 74  FKRLLGDGSDFGISISYAVQPSPDGLAQAFIIGEEFIGNDNVCLVLGDNIFYGQSFTQTL 133

Query: 118 EHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPI 177
           +   +  + A++   +V NP++FGV E +E+ + +  + EKP+ P S+ A+ G+YF+   
Sbjct: 134 KQAARQTHGATVFAYQVKNPERFGVVEFNENFRAVS-IEEKPQRPKSDWAVTGLYFYDNR 192

Query: 178 IHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLV 234
             E  + +KPS R ELEI+D  +  +++G         G+ W DTG  E L EA   V
Sbjct: 193 AVEFAKQLKPSARGELEISDLNRMYLEDGSLSVQILGRGFAWLDTGTHESLHEAASFV 250


>gb|AAG18702.1| (AE004975) glucose-1-phosphate thymidylyltransferase; GraD3
           [Halobacterium sp. NRC-1]
           Length = 238
           
 Score =  143 bits (357), Expect = 3e-33
 Identities = 86/236 (36%), Positives = 125/236 (52%), Gaps = 4/236 (1%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MKA++L+ G GTRLRP T    K L+ V  KP+L +  E +++ GI ++ ++VG  K+++
Sbjct: 1   MKAVVLAAGEGTRLRPRTADLPKPLVEVNGKPILTHCFEILLDLGIDDVVVVVGYEKDKI 60

Query: 61  IETVKSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKEHF 120
           I+         +IE+ +Q E  GLAHA+L A  Y+ + DFV+  GDNI          H 
Sbjct: 61  IDRYGDSFRAIDIEYAHQSERLGLAHAVLTAEPYV-DSDFVVLNGDNIYSANFSEVLAHH 119

Query: 121 EKSDYDASILLCEVPNPQ--QFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPII 178
            +S  D +  + EV   +     V EL +D + +  L+EKP  PPSN A    Y   P I
Sbjct: 120 TESGADITFPVEEVSTEEATSGAVCELDDD-RAVTGLVEKPAEPPSNYAPTAFYVLPPAI 178

Query: 179 HEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLV 234
             A R I+PS R E E+ DAI  LI +GY V      GW  +     D+  A +L+
Sbjct: 179 FPACRVIRPSERGEYELADAIDLLIYSGYSVETQPFEGWKVNVNTEADITRAEQLL 234


>gb|AAG09511.1|AF279618_3 (AF279618) glucose-1-phosphate thymidylyltransferase [Salmonella
           enterica]
           Length = 292
           
 Score =  143 bits (356), Expect = 4e-33
 Identities = 86/266 (32%), Positives = 143/266 (53%), Gaps = 6/266 (2%)

Query: 2   KALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQVI 61
           K +IL+GG GTRL P+T +  KQL+P+ +KP+++Y +  ++ AGI +I II  P      
Sbjct: 5   KGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPRF 64

Query: 62  ETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNIL-REGIVRHKE 118
           + +      W  N+++  Q  P GLA A ++  +++GNDD  + LGDNI     + +  +
Sbjct: 65  QQLLGDGSQWGLNLQYKVQPNPDGLAQAFIIGEEFIGNDDCALVLGDNIFYGHDLPKLMD 124

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPII 178
                +  A  +   V +P+++GV E  ++G  +  L EKP  P SN A+ G+YF+   +
Sbjct: 125 VAVNKENGAYGIAYHVNDPERYGVVEFDQNGTAVS-LEEKPLQPKSNYAVTGLYFYDNSV 183

Query: 179 HEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLVLDE 237
               +++KPS R ELEITD  +  ++ G         G+ W DTG  + L+EA+  +   
Sbjct: 184 VAMAKNLKPSARGELEITDINRIYMEQGRLSVAMMGRGYAWLDTGTHQSLIEASNFIATI 243

Query: 238 IERE-IKVETRAKIIGRVKIEEGAKI 262
            ER+ +KV    +I  R    +  K+
Sbjct: 244 EERQGLKVSCPEEIAYRKGFIDSQKV 269


>gb|AAB47843.1| (U61226) RfbA [Leptospira interrogans]
           >gi|5814321|gb|AAD52189.1|AF144879_28 (AF144879) unknown
           [Leptospira interrogans]
           Length = 294
           
 Score =  142 bits (354), Expect = 7e-33
 Identities = 88/269 (32%), Positives = 146/269 (53%), Gaps = 8/269 (2%)

Query: 2   KALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQVI 61
           K +IL+GG GTRL P+TY   KQL+PV +KP+++Y +  ++ AGI EI +I  P    + 
Sbjct: 5   KGIILAGGSGTRLYPVTYVVSKQLLPVYDKPMIYYPLTTLMLAGIKEILLISTPQATPMY 64

Query: 62  ETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNI-LREGIVRHKE 118
           + +      W  +IE+  Q  P GLA A  +  +++     V+ LGDNI     +    E
Sbjct: 65  KELLGDGKQWGISIEYAVQPNPGGLAQAYWIGENFVNGHPSVLILGDNIYFGHNLASLLE 124

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPII 178
           +  K +  +++    V +P+++GV E   + + +  + EKP  P SN A+ G+YF+   +
Sbjct: 125 NASKKENGSTVFAYPVHDPERYGVVEFDSERRAVS-IEEKPSKPKSNYAVTGLYFYDEEV 183

Query: 179 HEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLVLDE 237
               + IKPS R ELEITD  +  ++ G         G+ W DTG  E LLEA+ + ++ 
Sbjct: 184 VNIAKSIKPSARGELEITDVNRIYLERGILNVQVMGRGYAWLDTGTHESLLEAS-VFIET 242

Query: 238 IERE--IKVETRAKIIGRVKIEEGAKIDE 264
           IE+   +KV    +I  R    +G+++++
Sbjct: 243 IEKRQGLKVACPEEIAFRKGFIDGSQLEK 271


>gb|AAD12972.1| (AF078135) RmlA [Leptospira borgpetersenii]
           Length = 294
           
 Score =  142 bits (354), Expect = 7e-33
 Identities = 89/269 (33%), Positives = 146/269 (54%), Gaps = 8/269 (2%)

Query: 2   KALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQVI 61
           K +IL+GG GTRL P+TY   KQL+PV +KP+++Y +  ++ AGI EI +I  P    + 
Sbjct: 5   KGIILAGGSGTRLYPVTYVVSKQLLPVYDKPMIYYPLTTLMLAGIKEILLISTPQATPMY 64

Query: 62  ETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNI-LREGIVRHKE 118
           + +      W  +IE+  Q EP GLA A  +  +++     V+ LGDNI     +    E
Sbjct: 65  KELLGDGKQWGISIEYAVQPEPGGLAQAYWIGENFVNGHPSVLILGDNIYFGHNLAVLLE 124

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPII 178
           +  K    +++    V +P+++GV E   + + +  + EKP  P SN A+ G+YF+   +
Sbjct: 125 NASKKTKGSTVFAYPVHDPERYGVVEFDSERRAVS-IEEKPSKPKSNYAVTGLYFYDEEV 183

Query: 179 HEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLVLDE 237
               + IKPS R ELEITD  +  ++ G         G+ W DTG  E LLEA+ + ++ 
Sbjct: 184 VSIAKSIKPSARGELEITDVNRIYLERGILNVQVMGRGYAWLDTGTHESLLEAS-VFIET 242

Query: 238 IERE--IKVETRAKIIGRVKIEEGAKIDE 264
           IE+   +KV    +I  R    +G+++++
Sbjct: 243 IEKRQGLKVACPEEIAFRKGFIDGSQLEK 271


>sp|P57040|RFBA_NEIMA GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (DTDP-GLUCOSE SYNTHASE)
           (DTDP-GLUCOSE PYROPHOSPHORYLASE)
           >gi|11261721|pir||H82014 glucose-1-phosphate
           thymidylyltransferase (EC 2.7.7.24) NMA0205 [imported] -
           Neisseria meningitidis (group B strain MD58, group A
           strain Z2491) >gi|7378960|emb|CAB83503.1| (AL162752)
           glucose-1-phosphate thymidylyltransferase [Neisseria
           meningitidis Z2491] >gi|7378974|emb|CAB83519.1|
           (AL162752) glucose-1-phosphate thymidylyltransferase
           [Neisseria meningitidis Z2491]
           Length = 288
           
 Score =  142 bits (354), Expect = 7e-33
 Identities = 81/238 (34%), Positives = 133/238 (55%), Gaps = 5/238 (2%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK +IL+GG GTRL P+T    KQL+PV +KP+++Y +  ++ AGI +I +I  P     
Sbjct: 1   MKGIILAGGSGTRLYPITRGVSKQLLPVYDKPMIYYPLSVLMLAGIRDILVITAPEDNAS 60

Query: 61  IETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNIL-REGIVRHK 117
            + +     D+  +I +  Q  P GLA A ++  +++GND+  + LGDNI   +   +  
Sbjct: 61  FKRLLGDGSDFGISISYAVQPSPDGLAQAFIIGEEFIGNDNVCLVLGDNIFYGQSFTQTL 120

Query: 118 EHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPI 177
           +      + A++   +V NP++FGV E +E+ + +  + EKP+ P S+ A+ G+YF+   
Sbjct: 121 KQAAAQTHGATVFAYQVKNPERFGVVEFNENFRAVS-IEEKPQRPKSDWAVTGLYFYDNR 179

Query: 178 IHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLV 234
             E  + +KPS R ELEI+D  +  +++G         G+ W DTG  E L EA   V
Sbjct: 180 AVEFAKQLKPSARGELEISDLNRMYLEDGSLSVQILGRGFAWLDTGTHESLHEAASFV 237


>pir||H75070 sugar-phosphate nucleotydyl transferase PAB0645 - Pyrococcus abyssi
           (strain Orsay) >gi|5458381|emb|CAB49869.1| (AJ248286)
           SUGAR-PHOSPHATE NUCLEOTYDYL TRANSFERASE [Pyrococcus
           abyssi]
           Length = 413
           
 Score =  141 bits (353), Expect = 9e-33
 Identities = 106/348 (30%), Positives = 185/348 (52%), Gaps = 27/348 (7%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDV-----IEAGIHEIGIIVGP 55
           MKA+IL+GG+GTRLRP++ ++ K ++PV  KP L Y +E +     I+  I  +  + G 
Sbjct: 1   MKAVILAGGFGTRLRPISSTRPKPMVPVLGKPNLQYILEALEKVKEIDEVILSVHYMRGE 60

Query: 56  NKEQVIETVKSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVR 115
            +E + E ++  D+  +I F+    P     A+    +Y+ +DDF++  GD         
Sbjct: 61  IREFIQEKMR--DYPKDIRFVNDPMPLETGGALKNVEEYV-SDDFLVIYGDVFTNFDYSE 117

Query: 116 HKEHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFF- 174
             E  +K+D   ++ L +V +P++FGV    E+GK ++   EKP+ P +NL   GIY   
Sbjct: 118 LIEAHKKNDGLVTVALTKVYDPERFGVVITDEEGKIVE-FEEKPRKPKTNLVDAGIYMVN 176

Query: 175 RPIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLV 234
           + ++ E  ++ +  +  E+      Q L+  GYK+       +W D G PED   A+++ 
Sbjct: 177 KDVLKEIPKNKEVYFEREILPKFVSQGLV-YGYKM---PKHYYWVDLGTPEDFFYAHQIA 232

Query: 235 LDEIERE---------IKVETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRN-AY 284
           LDE+ RE         +++    ++ G V I++ AKI     IK    IG N +I + AY
Sbjct: 233 LDEMARENGYMILGENVEIPEDVEVQGPVYIDDNAKIGHGVKIKAYTYIGPNTMIEDKAY 292

Query: 285 IGPYTSVGNNVVIEDTEVEDSIIMDGSVIIGAGRIIE--SIIGKEVRI 330
           I     +GN+++ E  E++D+I+ +G V++G   II+  ++IG   +I
Sbjct: 293 IKRAILLGNDIIKERAELKDTILGEG-VVVGKNVIIKENAVIGDYAKI 339


>sp|P55464|RFBA_RHISN PROBABLE GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (DTDP-GLUCOSE
           SYNTHASE) (DTDP-GLUCOSE PYROPHOSPHORYLASE)
           >gi|2182410|gb|AAB91682.1| (AE000074) Y4gH [Rhizobium
           sp. NGR234]
           Length = 286
           
 Score =  141 bits (352), Expect = 1e-32
 Identities = 93/272 (34%), Positives = 140/272 (51%), Gaps = 9/272 (3%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK +IL+GG GTRL P+T    KQ++PV +KP++FY +  ++ AGI EI II  P+   +
Sbjct: 1   MKGIILAGGSGTRLHPMTLVMSKQILPVYDKPMIFYPLTTLMLAGIREILIISTPHHMPL 60

Query: 61  IETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNI-LREGIVRHK 117
            + +      W  ++ +  Q  P GLA A ++  D++      + LGDNI    G+    
Sbjct: 61  FQALLGDGSQWGISLRYAVQPSPNGLAQAYVIGADFVAGSPSCLILGDNIYFGHGLQGLL 120

Query: 118 EHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPI 177
           +        A+I    V +P+++GV E  E G     + EKP  P S  A+ G+YF+   
Sbjct: 121 QQAAALQQGATIFAYHVNDPERYGVVEFDE-GMNALSIEEKPAAPKSTWAVTGLYFYDSE 179

Query: 178 IHEAVRHIKPSWRNELEITDAIQWLIDNG-YKVGWTKVTGWWKDTGKPEDLLEANRLVLD 236
           + +   ++KPS R E EITD  +  ++ G  KV        W DTG P+ LLEA   V  
Sbjct: 180 VVDIAANLKPSARGEYEITDVNRIYLERGKLKVAVLGRGYAWLDTGTPDSLLEAAEFVRT 239

Query: 237 -EIEREIKV---ETRAKIIGRVKIEEGAKIDE 264
            E  +  KV   E  A  +G + +EE A+I E
Sbjct: 240 LEKRQAFKVACPEEVALAMGFISVEEFARIAE 271


>sp|P27831|RFFH_ECOLI GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (DTDP-GLUCOSE SYNTHASE)
           (DTDP-GLUCOSE PYROPHOSPHORYLASE) >gi|7434864|pir||H65182
           glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24)
           - Escherichia coli >gi|1790224|gb|AAC76794.1| (AE000455)
           glucose-1-phosphate thymidylyltransferase [Escherichia
           coli K12]
           Length = 293
           
 Score =  141 bits (351), Expect = 2e-32
 Identities = 83/238 (34%), Positives = 129/238 (53%), Gaps = 5/238 (2%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK +IL+GG GTRL P+T    KQL+P+ +KP+++Y +  ++ AGI EI II  P  +  
Sbjct: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60

Query: 61  IETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNI-LREGIVRHK 117
            + +     ++   +E+  Q  P GLA A ++   +L  +   + LGDNI   +G     
Sbjct: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120

Query: 118 EHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPI 177
            H       A++   +V +P++FGV E  ++ + I  L EKPK P SN A+ G+YF+   
Sbjct: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAIS-LEEKPKQPKSNWAVTGLYFYDSK 179

Query: 178 IHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLV 234
           + E  + +KPS R ELEIT   Q  ++ G         G+ W DTG  + L+EA+  V
Sbjct: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237


>gb|AAD40709.1|AF048749_5 (AF048749) glucose-1-phosphate thymidyl transferase [Bacteroides
           fragilis]
           Length = 295
           
 Score =  139 bits (348), Expect = 3e-32
 Identities = 86/241 (35%), Positives = 132/241 (54%), Gaps = 8/241 (3%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK ++L+GG GTRL P+T    KQL+P+ +KP+++Y I  ++ AGI EI II  P+    
Sbjct: 1   MKGIVLAGGSGTRLYPITKGVSKQLLPIFDKPMIYYPISVLMLAGIREILIISTPDDLPG 60

Query: 61  IETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNIL-REGIVR-- 115
            + +     D+    E+  Q  P GLA A ++   ++G+D   + LGDNI   +G  R  
Sbjct: 61  FQRLLGDGSDFGVRFEYAEQPSPDGLAQAFIIGEKFIGDDSVCLVLGDNIFYGQGFTRML 120

Query: 116 -HKEHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFF 174
                  +S+  A++    V +P+++GVAE  E+G     + EKP+ P SN A+VG+YF+
Sbjct: 121 NEAVRIAESESKATVFGYWVSDPERYGVAEFDENGNVFS-IEEKPQKPKSNYAVVGLYFY 179

Query: 175 RPIIHEAVRHIKPSWRNELEITDAIQ-WLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRL 233
              + E  + I+PS R ELEIT   Q +L D   +V        W DTG  + L EA+  
Sbjct: 180 PNKVVEVAKSIRPSSRGELEITTVNQNFLSDKELRVQLLGRGFAWLDTGTHDSLSEASTF 239

Query: 234 V 234
           +
Sbjct: 240 I 240


>gb|AAF01820.1|AF187532_16 (AF187532) putative dTDP-glucose synthase [Streptomyces nogalater]
           Length = 293
           
 Score =  139 bits (348), Expect = 3e-32
 Identities = 84/245 (34%), Positives = 136/245 (55%), Gaps = 5/245 (2%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK +IL+GG G+RL P T +  KQL+PV +KP+++Y +  ++ AG+ +I II  P++   
Sbjct: 1   MKGIILAGGTGSRLHPTTLAVSKQLLPVGDKPMIYYPLSVLMLAGVTDILIISTPHELPR 60

Query: 61  IETVKSVDWDANIEFIY--QGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKE 118
           +  +        +   Y  Q +P+G+A A L+  D++G+D   + LGDNI      +   
Sbjct: 61  MRRLFGDGAQLGLRLAYAEQEKPRGIAEAFLIGADHVGSDAVALALGDNIFHGSSFQGVL 120

Query: 119 HFEKSDYDASILL-CEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPI 177
             E  + D  +L    V +PQ++GV E +  G+ +  + EKP  P SN A+ G+YF+   
Sbjct: 121 RKEAEELDGCVLFGYPVKDPQRYGVGEANASGRLVS-IEEKPVRPRSNRAITGLYFYDNE 179

Query: 178 IHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLVLD 236
           + +  R ++PS R ELEITD  +  ++ G         G+ W DTG PE LL+A++ V  
Sbjct: 180 VVDIARRLRPSARGELEITDINRTYMERGRARLVDLGRGFAWLDTGTPESLLQASQYVSA 239

Query: 237 EIERE 241
             ER+
Sbjct: 240 LEERQ 244


>emb|CAA80332.1| (Z22611) OAC3 [Azorhizobium caulinodans]
           Length = 213
           
 Score =  139 bits (347), Expect = 4e-32
 Identities = 76/209 (36%), Positives = 124/209 (58%), Gaps = 4/209 (1%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK +IL+GG GTRL P+T    KQL+PV +KP+++Y +  ++ AGI +I II  P+  ++
Sbjct: 1   MKGIILAGGSGTRLHPITLVVSKQLLPVYDKPMIYYPLCTLMMAGIRDILIITTPHDSEL 60

Query: 61  IETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNI-LREGIVRHK 117
            + +      +  NI +  Q  P+GLA A +V R+++GND   + LGDN+    G+    
Sbjct: 61  FQKLLKDGSQFGLNISYAVQPSPRGLADAFIVGREFVGNDRVALVLGDNLFFGHGLPELL 120

Query: 118 EHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPI 177
           +  +  +  A++    V +P+++GV E+ E GK +  L EKP  P SNLA+ G+YF+   
Sbjct: 121 KTAQARETGATVFGYPVTDPERYGVVEMDETGKVLS-LEEKPLKPKSNLAVTGLYFYDNR 179

Query: 178 IHEAVRHIKPSWRNELEITDAIQWLIDNG 206
           + +   ++ PS R E+EITD  +  +D G
Sbjct: 180 VVDIAANLAPSPRGEIEITDVNKAYLDLG 208


>pir||C36864 probable glucose-1-phosphate thymidylyltransferase - Azorhizobium
           caulinodans (fragment)
           Length = 210
           
 Score =  139 bits (347), Expect = 4e-32
 Identities = 76/209 (36%), Positives = 124/209 (58%), Gaps = 4/209 (1%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK +IL+GG GTRL P+T    KQL+PV +KP+++Y +  ++ AGI +I II  P+  ++
Sbjct: 1   MKGIILAGGSGTRLHPITLVVSKQLLPVYDKPMIYYPLCTLMMAGIRDILIITTPHDSEL 60

Query: 61  IETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNI-LREGIVRHK 117
            + +      +  NI +  Q  P+GLA A +V R+++GND   + LGDN+    G+    
Sbjct: 61  FQKLLKDGSQFGLNISYAVQPSPRGLADAFIVGREFVGNDRVALVLGDNLFFGHGLPELL 120

Query: 118 EHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPI 177
           +  +  +  A++    V +P+++GV E+ E GK +  L EKP  P SNLA+ G+YF+   
Sbjct: 121 KTAQARETGATVFGYPVTDPERYGVVEMDETGKVLS-LEEKPLKPKSNLAVTGLYFYDNR 179

Query: 178 IHEAVRHIKPSWRNELEITDAIQWLIDNG 206
           + +   ++ PS R E+EITD  +  +D G
Sbjct: 180 VVDIAANLAPSPRGEIEITDVNKAYLDLG 208


>pir||A71095 probable sugar-phosphate nucleotydyl transferase - Pyrococcus
           horikoshii >gi|3257436|dbj|BAA30119.1| (AP000004) 416aa
           long hypothetical sugar-phosphate nucleotydyl
           transferase [Pyrococcus horikoshii]
           Length = 416
           
 Score =  139 bits (347), Expect = 4e-32
 Identities = 105/346 (30%), Positives = 184/346 (52%), Gaps = 23/346 (6%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEA-GIHEIGIIVGPNKEQ 59
           MKA+IL+GG+GTRLRP++ ++ K ++PV  KP L Y +E + +   I EI + V   + +
Sbjct: 4   MKAVILAGGFGTRLRPISSTRPKPMVPVLGKPNLQYILEALEKVKEIDEIILSVHYMRGE 63

Query: 60  VIETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHK 117
           + E +  K  D+  +I F+    P     A+    +Y+ +DDF++  GD           
Sbjct: 64  IREFIQEKMRDYPKDIRFVNDPMPLETGGALKNVEEYV-SDDFLVIYGDVFTNFDYSELI 122

Query: 118 EHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFF-RP 176
           E  +K+D   ++ L +V +P++FGV    E+GK ++   EKP+ P +NL   GIY   + 
Sbjct: 123 EAHKKNDGLITVALTKVYDPERFGVVITDEEGKIVE-FEEKPRKPKTNLVDAGIYMVNKD 181

Query: 177 IIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLD 236
           ++ E  ++ +  +  E+      Q L+  GYK+       +W D G PED   A+++ LD
Sbjct: 182 VLKEIPKNKEIYFEREILPKFVNQGLV-YGYKM---PKQYYWVDLGTPEDFFYAHQIALD 237

Query: 237 EIERE---------IKVETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRN-AYIG 286
           E+ +E         +++    ++ G V I++ AKI     IK    IG N +I + AY  
Sbjct: 238 ELSKENGYMILGENVEIPDDVEVQGPVYIDDNAKIGHGVKIKAYTYIGPNTIIEDKAYFK 297

Query: 287 PYTSVGNNVVIEDTEVEDSIIMDGSVIIGAGRIIE--SIIGKEVRI 330
               +GN+++ E  E++D+I+ +G V++G   II+  ++IG   +I
Sbjct: 298 RSILLGNDIIKERAELKDAILGEG-VVVGKDVIIKENAVIGDYAKI 342


>pir||B75008 glucose-1-phosphate thymidylyltransferase (grad-1) PAB1053 -
           Pyrococcus abyssi (strain Orsay)
           >gi|5459018|emb|CAB50504.1| (AJ248288)
           glucose-1-phosphate thymidylyltransferase (graD-1)
           [Pyrococcus abyssi]
           Length = 332
           
 Score =  139 bits (347), Expect = 4e-32
 Identities = 110/342 (32%), Positives = 172/342 (50%), Gaps = 18/342 (5%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK LI++GGY TRL PLT  + K L+PV  K +L + +E V+E  + E+ I      E  
Sbjct: 1   MKVLIMAGGYATRLWPLTKDKPKPLLPVGIKTILDFIMEKVLELNVDEVYISTNKFFEHK 60

Query: 61  IET-VKSVDWDANIEFIYQGEPK-GLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKE 118
            +   +    D  IE  Y+ E K G   AI  A D LG DD+++  GDNI    +     
Sbjct: 61  FKPYAEKYGVDLIIEDTYREEEKLGTIGAIKNALDSLGLDDYLIIAGDNIFSLSLRDFVS 120

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFF-RPI 177
            F      A   + ++   +++GV  L  +G  + + IEKP+ PPS L   GIY   R +
Sbjct: 121 KFTGKPLIAVYDVGDLELAKRYGVVIL--EGNRVVKFIEKPQEPPSTLISTGIYALPRDV 178

Query: 178 IHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLDE 237
           +     ++K  + N+      IQWLI+ G +V   K   +W D G  +  LE+ ++++ E
Sbjct: 179 MGMIDEYLK--YGNKDAPGYFIQWLIERGIEVYAYKFDDFWYDIGSADSYLESLKMLMKE 236

Query: 238 -IEREIKVETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSVGNNVV 296
               +IKV   +KII  V I +G +I+  +II   A IGRN +I N      + V ++++
Sbjct: 237 SYIGDIKVSPYSKIIPPVVILDGTRIEGRSIIGPFAYIGRNCLIEN------SDVSDSII 290

Query: 297 IEDTEVEDSI----IMDGSVIIGAGRIIESIIGKEVRIVRGD 334
            + T + +S     I+D    I    + +SI+G   +I RGD
Sbjct: 291 FDSTVIRNSTIWRSIIDEKCEIRNLELKKSIVGGHAKIQRGD 332


>gb|AAD56730.1|AF125164_3 (AF125164) glucose-1-phosphate thymidyltransferase [Bacteroides
           fragilis]
           Length = 294
           
 Score =  138 bits (345), Expect = 8e-32
 Identities = 86/241 (35%), Positives = 131/241 (53%), Gaps = 8/241 (3%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK ++L+GG GTRL P+T    KQL+P+ +KP+++Y I  ++ AGI EI II  P+    
Sbjct: 1   MKGIVLAGGSGTRLYPITKGVSKQLLPIFDKPMIYYPISVLMLAGIREILIISTPDDLPG 60

Query: 61  IETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKE 118
            + +     D+    E+  Q  P GLA A ++   ++G+D   + LGDNI     +    
Sbjct: 61  FQRLLGDGSDFGVRFEYAEQPSPDGLAQAFIIGEKFIGDDSVCLVLGDNIFYGDGLTEMV 120

Query: 119 HF--EKSDYD--ASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFF 174
            F   K+D +  A++    V +P+++GVAE    G  +  + EKP+ P SN A+VG+YF+
Sbjct: 121 QFAVNKADLENKATVFGYWVSDPERYGVAEFDRSGNVLS-IEEKPQKPKSNYAIVGLYFY 179

Query: 175 RPIIHEAVRHIKPSWRNELEITDAIQWLIDN-GYKVGWTKVTGWWKDTGKPEDLLEANRL 233
              + E  ++IKPS R ELEIT   Q  + N   KV        W DTG  + L EA+  
Sbjct: 180 PNKVVEVAKNIKPSSRGELEITTVNQRFLSNRELKVQLLGRGFAWLDTGTHDSLSEASTF 239

Query: 234 V 234
           +
Sbjct: 240 I 240


>pir||A70363 mannose-1-phosphate guanyltransferase - Aquifex aeolicus
           >gi|2983302|gb|AAC06893.1| (AE000704)
           mannose-1-phosphate guanyltransferase [Aquifex aeolicus]
           Length = 831
           
 Score =  138 bits (344), Expect = 1e-31
 Identities = 108/351 (30%), Positives = 175/351 (49%), Gaps = 31/351 (8%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK +IL+GG+GTR++PLT S  K ++PVAN+P++ + +  + EAGI EI +++    E +
Sbjct: 1   MKGVILAGGFGTRIQPLTNSIPKPMLPVANRPIMEHVVHRLKEAGIEEIVVLLYYQAEVI 60

Query: 61  IETVK-SVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNI----LREGIVR 115
               K   D+   I ++      G A A+  A++YL N+ F++  GD I    L E I  
Sbjct: 61  KNYFKDGSDFGVKITYVQPEADYGTAGAVKQAQNYL-NETFIIVSGDVITDFNLSELIAF 119

Query: 116 HKEHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPP--SNLALVGIYF 173
           HK    K     ++ L  V NP QFGV   +++GK +K  +EKP      S+    GIY 
Sbjct: 120 HKSKSSK----FTLALYSVENPLQFGVVITNKEGKVLK-FLEKPGWGEVFSDTVNTGIYV 174

Query: 174 FRPIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRL 233
             P I   +   KP         D    L+ +G  +   K+ G+W+D G  +   + ++ 
Sbjct: 175 VEPEILNYIPEDKPF----DFAMDLFPKLMKSGIDLWALKMRGYWRDIGNIDSYRDVHK- 229

Query: 234 VLDEIEREIKVETRAKII----GRVKIEEGAKIDENTIIKGPAVIGRN------AVIRNA 283
             D     +K+    +II     R+ +EEG +I EN  +KG  ++G+N      + ++N 
Sbjct: 230 --DIFAGLVKIRIPGRIITTKEARIYVEEGTEIPENVSLKGTVILGKNVKVGEGSELKNC 287

Query: 284 YIGPYTSVGNNVVIEDTEVEDSIIMDGSVIIGAGRIIESI-IGKEVRIVRG 333
            IG  T +G NV + D+ +  ++ +D    I  G I   + IGK V+   G
Sbjct: 288 VIGNNTVIGRNVKLFDSVLWWNVSIDEESEIRNGVICNDVKIGKRVKAKEG 338


>sp|P37779|RFBA_SHIFL GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (DTDP-GLUCOSE SYNTHASE)
           (DTDP-GLUCOSE PYROPHOSPHORYLASE) >gi|541220|pir||S41536
           glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24)
           - Shigella flexneri (serotype 2a)
           >gi|454900|emb|CAA50769.1| (X71970) rfbC [Shigella
           flexneri]
           Length = 290
           
 Score =  138 bits (343), Expect = 1e-31
 Identities = 81/255 (31%), Positives = 136/255 (52%), Gaps = 4/255 (1%)

Query: 2   KALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQVI 61
           K +IL+GG GTRL P+T +  KQL+P+ +KP+++Y +  ++ AGI +I II  P      
Sbjct: 5   KGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPRF 64

Query: 62  ETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNIL-REGIVRHKE 118
           + +      W  N+++  Q  P GLA A ++  +++G DD  + LGDNI     + +  +
Sbjct: 65  QQLLGDGSQWGLNLQYKVQPSPDGLAQAFIIGEEFIGGDDCALVLGDNIFYGHDLPKLMD 124

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPII 178
                +  A++    V +P+++GV E  ++G  I  L EKP+ P SN A+ G+YF+   +
Sbjct: 125 TAVNRESGATVFAYHVNDPERYGVVEFDDNGTPIS-LEEKPQQPKSNYAVTGLYFYDNDV 183

Query: 179 HEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLDEI 238
            E  +++KPS R ELEITD  +  +D G             DT   + +  +N +  +E 
Sbjct: 184 VEMAKNLKPSARGELEITDINRIYMDQGRLSAMMGRGYACLDTDTSKPIEASNFIATNED 243

Query: 239 EREIKVETRAKIIGR 253
            + +KV    +I  R
Sbjct: 244 RQGLKVSCPEEIAHR 258


>emb|CAC01394.1| (AJ131360) glucose-1-phosphate thymidyltransferase [Campylobacter
           jejuni]
           Length = 307
           
 Score =  138 bits (343), Expect = 1e-31
 Identities = 89/244 (36%), Positives = 138/244 (56%), Gaps = 15/244 (6%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK +IL+GG GTRL P T +  KQL+P+ +KP+++Y +  ++ A I E+ II  P     
Sbjct: 16  MKGIILAGGSGTRLYPSTLTLCKQLLPIYDKPMIYYPMSVLMLAKIKEVLIISTPKD--- 72

Query: 61  IETVKSVDWDAN-----IEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILR----E 111
           I+  K +  D +     I++  Q  P+GLA  +++A+D++ NDD  + LGDNI       
Sbjct: 73  IDRFKELFKDGSFLGMQIQYKIQERPEGLAQGLILAQDFIQNDDIALILGDNIFYGQGFS 132

Query: 112 GIVRHKEHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGI 171
            I+ + +   K  + ASI    V +P++FGV E+ ++G  +  L EKPK+P SN    G+
Sbjct: 133 DILENAKDDLKKGF-ASIFSYHVKDPERFGVVEMDQNGNVLS-LEEKPKNPKSNHVATGL 190

Query: 172 YFFRPIIHEAVRHIKPSWRNELEITDA-IQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEA 230
           YF+     +  +++KPS R ELEITD  I++L  N  K         W DTG  + L+EA
Sbjct: 191 YFYNNDAIDIAKNVKPSARGELEITDVNIEYLRLNKLKSQHLGRGFAWIDTGTHDSLIEA 250

Query: 231 NRLV 234
           +  V
Sbjct: 251 SSFV 254


>gb|AAC68682.1| (AF079762) alpha-D-glucose-1-phosphate thymidylyltransferase
           [Streptomyces venezuelae]
           Length = 292
           
 Score =  136 bits (340), Expect = 3e-31
 Identities = 90/254 (35%), Positives = 138/254 (53%), Gaps = 23/254 (9%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK ++L+GG GTRL P T    KQ++PV NKP+++Y +  ++  GI EI II  P   ++
Sbjct: 1   MKGIVLAGGSGTRLHPATSVISKQILPVYNKPMIYYPLSVLMLGGIREIQIISTPQHIEL 60

Query: 61  IETVKSVDWDANIEFIY--QGEPKGLAHAILVARDYLGNDDFVMYLGDNI---------L 109
            +++        IE  Y  Q EP G+A A+LV  +++G+D   + LGDNI         L
Sbjct: 61  FQSLLGNGRHLGIELDYAVQKEPAGIADALLVGAEHIGDDTCALILGDNIFHGPGLYTLL 120

Query: 110 REGIVRHKEHFEKSDYDASILL-CEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLAL 168
           R+ I R          D  +L    V +P+++GVAE+   G+ +  L+EKP  P SNLA+
Sbjct: 121 RDSIAR---------LDGCVLFGYPVKDPERYGVAEVDATGR-LTDLVEKPVKPRSNLAV 170

Query: 169 VGIYFFRPIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDL 227
            G+Y +   + +  ++I+PS R ELEITD  +  ++ G         G+ W DTG  + L
Sbjct: 171 TGLYLYDNDVVDIAKNIRPSPRGELEITDVNRVYLERGRAELVNLGRGFAWLDTGTHDSL 230

Query: 228 LEANRLVLDEIERE 241
           L A + V    ER+
Sbjct: 231 LRAAQYVQVLEERQ 244


>gb|AAG18650.1| (AE004970) glucose-1-phosphate thymidylyltransferase; GraD5
           [Halobacterium sp. NRC-1]
           Length = 395
           
 Score =  136 bits (339), Expect = 4e-31
 Identities = 103/365 (28%), Positives = 183/365 (49%), Gaps = 22/365 (6%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           M+A++L+ G G RL PLT ++ K ++PVAN+P+L + ++ ++ AG+  + ++VG N+E+V
Sbjct: 1   MQAVVLAAGKGERLWPLTENRPKPMVPVANQPILEHIVDALVSAGVTRVMLVVGSNRERV 60

Query: 61  IETVKSVD-WDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKEH 119
               +    W   I ++ Q    G  HA+  A   +G + FV   GD ++   +V     
Sbjct: 61  QRHFEDGSRWGIEISYVVQDRQLGTGHALAQAESVVG-ESFVALNGDRVIDASLVEDVWE 119

Query: 120 FEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEK--PKHPPSNLALVGIYFFRPI 177
             +   D+++ + +V  P  +GV +L  DG T+  + E+  P+   S     G+Y F P 
Sbjct: 120 CHRESGDSAMGVTQVETPSAYGVVDL--DGGTVTDIDEQPVPELVASEYINAGVYAFGPS 177

Query: 178 IHEAVRHIKPSWRNELEITDAI-QWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLD 236
           +  A+R  +     EL +TDA+ + L D+  +    +  G W D  +P DL+ AN  ++ 
Sbjct: 178 VFAAIR--RTDSYGELALTDALDEQLADHELRA--VRYDGRWLDVSEPWDLVAANSALIT 233

Query: 237 EIEREIKVETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAY-IGPYTSVGNNV 295
           +   +  VE R         ++ A +   T+     ++   AV+RN   +G   +VG N 
Sbjct: 234 DRRFDPPVERRKPRGSVPGDDQQAPVGGGTVCGEGVIVHPQAVVRNGVALGDNVTVGANA 293

Query: 296 VIEDT-EVEDSIIMDGSV----IIGAGRII---ESIIGKEVRIVRGDGHPLGRRL--IVG 345
           VIE +  + DS +  G+V    I+GA   I    ++ G +  +V GD    G R   +VG
Sbjct: 294 VIEQSILLPDSTVNPGAVVNDSIVGANATIGPNTTVEGGQTDVVLGDTVHQGVRFGALVG 353

Query: 346 DKSQL 350
           D +++
Sbjct: 354 DNAEV 358


>gb|AAC70774.1| (AF097519) glucose-1-phosphate thymidylyl transferase [Klebsiella
           pneumoniae]
           Length = 301
           
 Score =  136 bits (338), Expect = 5e-31
 Identities = 80/238 (33%), Positives = 129/238 (53%), Gaps = 5/238 (2%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK ++L+GG GTRL P+T    KQL+P+ +KP++FY +  ++ AGI +I II  P+    
Sbjct: 1   MKGIVLAGGSGTRLYPITQGVSKQLLPIYDKPMIFYPVSVLMLAGIRDILIISTPDDMPS 60

Query: 61  IETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNI-LREGIVRHK 117
            + +      +  N  +  Q  P GLA A ++   ++GND   + LGDNI   +   +  
Sbjct: 61  FQRLLGDGSQFGVNFSYAIQPSPDGLAQAFIIGEKFIGNDACALVLGDNIYFGQSFGKKL 120

Query: 118 EHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPI 177
           E        A++   +V +P++FGV E  E+ K +  + EKP  P SN A+ G+YF+   
Sbjct: 121 EPAAAKTSGATVFGYQVLDPERFGVVEFDENFKALS-IEEKPLKPKSNWAVTGLYFYDNN 179

Query: 178 IHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLV 234
           + E  + +KPS R ELEIT   Q  ++ G         G+ W DTG  + L++A++ +
Sbjct: 180 VVEMAKDVKPSARRELEITTLNQMYLERGDLHVELLGRGFAWLDTGTHDSLMDASQFI 237


>gb|AAD28705.2|AF101047_6 (AF101047) putative glucose-1-phosphate thymidyl transferase
           [Haemophilus ducreyi]
           Length = 295
           
 Score =  135 bits (337), Expect = 7e-31
 Identities = 85/238 (35%), Positives = 128/238 (53%), Gaps = 5/238 (2%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK +IL+GG GTRL P+T    KQL+PV NKP+++Y +  ++ AGI EI +I  P   Q 
Sbjct: 2   MKGIILAGGSGTRLYPITRGISKQLLPVYNKPMIYYPLSVLMLAGIREILVITTPVDHQH 61

Query: 61  IETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNIL-REGIVRHK 117
            + +      +  +I++  Q +P GLA A ++   ++G D+  + LGDNI   +G  +  
Sbjct: 62  FKALLGDGSHFGIHIDYAIQAKPAGLAEAFIIGEPFIGKDNVCLVLGDNIFYGQGFTQIL 121

Query: 118 EHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPI 177
                    A++   +V NP +FGV E  +D + I  L EKP+ P S+ A+ G+YF+   
Sbjct: 122 SVAANRQQGATLFGYQVNNPARFGVVEFDQDLR-ILTLEEKPQKPKSDWAVTGLYFYDNR 180

Query: 178 IHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLV 234
           + E  + + PS R ELEITD  Q  +  G         G+ W DTG  + L EA   V
Sbjct: 181 VIEFAKQVTPSARGELEITDINQRYLQEGMLHLQLLGRGFAWFDTGTCDSLHEAAAFV 238


>emb|CAC12985.1| (AJ250327) glucose-1-phosphate thymidyltransferase [Acetobacter
           xylinus]
           Length = 306
           
 Score =  135 bits (337), Expect = 7e-31
 Identities = 82/237 (34%), Positives = 127/237 (52%), Gaps = 5/237 (2%)

Query: 2   KALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQVI 61
           K ++L+GG GTR+ P+T +  KQL+PV +KP++FY +  ++ AGI +I II  P    + 
Sbjct: 11  KGILLAGGSGTRMHPMTQAVSKQLLPVYDKPMIFYPLSTLMLAGIRDIMIISTPADLPLF 70

Query: 62  ETVKSVDWDANIEFIY--QGEPKGLAHAILVARDYLGNDDFVMYLGDN-ILREGIVRHKE 118
                   D  + F Y  Q  P G+A AI++A D+L +    + LGDN I  + + R   
Sbjct: 71  RRFVGDGSDMGVTFTYREQPSPDGIAQAIVIADDWLDDAPCALILGDNLIFADHLGRQLR 130

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPII 178
                    ++   EV +P+++GV   S DG  +  ++EKP  P SN A+ G+YF+   +
Sbjct: 131 EAAARPTGDTVFAYEVRDPERYGVVSFSADGHALD-IVEKPTSPQSNWAVTGLYFYDGRV 189

Query: 179 HEAVRHIKPSWRNELEITDAIQ-WLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLV 234
            E  R +KPS R ELEITD  + +L  +   V        W D G P+ L++A + V
Sbjct: 190 REYARSLKPSSRGELEITDLNRIYLQKDDLHVQRLGRGCAWLDAGMPDSLMQAGQFV 246


>gb|AAD01737.1| (AF022716) GDP-mannose pyrophosphorylase [Solanum tuberosum]
           Length = 361
           
 Score =  134 bits (334), Expect = 2e-30
 Identities = 103/365 (28%), Positives = 173/365 (47%), Gaps = 43/365 (11%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MKALIL GG+GTRLRPLT S  K L+  ANKP++ + IE +   G+ E+ + +    E +
Sbjct: 1   MKALILVGGFGTRLRPLTLSVPKPLVEFANKPMILHQIEALKAVGVTEVVLAINYQPEVM 60

Query: 61  IETVKSVDWDANIEFI--YQGEPKGLAHAILVARDYLGND--DFVMYLGDNILREGIVRH 116
           +  +K  +    I+     + EP G A  + +ARD L +D  +    L  +++ E   + 
Sbjct: 61  LNFLKEFEASLGIKITCSQETEPLGTAGPLALARDKLIDDSGEPFFVLNSDVISEYPFKE 120

Query: 117 KEHFEKS-DYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFR 175
              F KS   +AS+++ +V  P ++GV  + E    ++R +EKPK    N    G Y   
Sbjct: 121 MIQFHKSHGGEASLMVTKVDEPSKYGVVVMEESTGQVERFVEKPKLFVGNKINAGFYLLN 180

Query: 176 PIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVL 235
           P + + ++ ++P+      I   +   I    K+    + G+W D G+P D +   RL L
Sbjct: 181 PSVLDRIQ-LRPT-----SIEKEVFPKIAAEKKLYAMVLPGFWMDIGQPRDYITGLRLYL 234

Query: 236 DEIEREI--KVETRAKIIGRVKIEEGAKIDENTIIKGPAVIG------------------ 275
           D +++    K+ +   I+G V ++E AKI E  +I     IG                  
Sbjct: 235 DSLKKHSSPKLASGPHIVGNVIVDESAKIGEGCLIGPDVAIGSGCVIESGVRLSRCTVMR 294

Query: 276 -----RNAVIRNAYIGPYTSVGN-------NVVIEDTEVEDSIIMDGSVIIGAGRIIESI 323
                ++A I  + IG +++VG         ++ ED  V D I  +G V++    I  SI
Sbjct: 295 GVRIKKHACISGSIIGWHSTVGQWARVENMTILGEDVHVCDEIYSNGGVVLPHKEIKSSI 354

Query: 324 IGKEV 328
           +  E+
Sbjct: 355 LKPEI 359


>gb|AAF73461.1|AF264025_12 (AF264025) putative dTDP-1-glucose synthase; AknY [Streptomyces
           galilaeus]
           Length = 291
           
 Score =  134 bits (334), Expect = 2e-30
 Identities = 88/254 (34%), Positives = 136/254 (52%), Gaps = 23/254 (9%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK +IL+GG GTRL P+T S  KQL+PV +KP+++Y +  ++ A I EI +I     E+ 
Sbjct: 1   MKGIILAGGSGTRLHPITVSVSKQLLPVGDKPMIYYPLSVLMLADIREILLIC---TERD 57

Query: 61  IETVKSVDWDAN-----IEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVR 115
           +E  + +  D +     I++  Q  P GLA A ++  D++G+DD  + LGDNI       
Sbjct: 58  LEQFRRLLGDGSQLGLRIDYAVQNRPAGLADAFVIGADHVGDDDVALVLGDNIF------ 111

Query: 116 HKEHF------EKSDYDASILL-CEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLAL 168
           H  HF         D    +L    V +P+++GV E    G+ +  L EKP  P S+LA+
Sbjct: 112 HGHHFYDLLQSNVHDVQGCVLFGYPVEDPERYGVGETDASGQLVS-LEEKPLRPRSDLAI 170

Query: 169 VGIYFFRPIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDL 227
            G+Y +   + +  ++++PS R ELEITD  +  +  G         G+ W D G PE L
Sbjct: 171 TGLYLYDNEVVDIAKNLRPSPRGELEITDVNRNYLARGRARLVDLGRGFAWLDAGTPESL 230

Query: 228 LEANRLVLDEIERE 241
           L+A + V    ER+
Sbjct: 231 LQATQYVRTLEERQ 244


>gb|AAD05455.1| (AF064070) putative glucose-1-phosphate thymidyltransferase
           [Burkholderia pseudomallei]
           Length = 297
           
 Score =  134 bits (333), Expect = 2e-30
 Identities = 78/233 (33%), Positives = 123/233 (52%), Gaps = 5/233 (2%)

Query: 2   KALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQVI 61
           K +IL+GG GTRL P+T++  KQL+PV +KP+++Y +  ++ A I ++ II  P      
Sbjct: 4   KGIILAGGSGTRLYPITHAVSKQLLPVYDKPMIYYPLSTLMVADIRDVLIISTPQDTPRF 63

Query: 62  ETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNIL-REGIVRHKE 118
           E +      W  NI +  Q  P GLA A ++ R+++G D   + LGDNI     + +  +
Sbjct: 64  EAMLGDGSQWGMNIRYAVQPSPDGLAQAFVIGREFVGRDPSTLILGDNIFYGHDLAKQLD 123

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPII 178
                   A++    V +P+++GV E   + + +  + EKP  P SN A+ G+YF+   +
Sbjct: 124 RASARQAGATVFAYHVHDPERYGVVEFDGEFRALS-IEEKPAKPRSNYAVTGLYFYDNQV 182

Query: 179 HEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEA 230
            +    IKPS R ELEITD     +  G         G+ W DTG  + L+EA
Sbjct: 183 CDIAADIKPSARGELEITDVNSRYLAAGLLDVEIMGRGYAWLDTGTHDSLIEA 235


>pir||T47698 mannose-1-phosphate guanylyltransferase-like protein - Arabidopsis
           thaliana >gi|7076802|emb|CAB75917.1| (AL132975)
           mannose-1-phosphate guanylyltransferase-like protein
           [Arabidopsis thaliana]
           Length = 364
           
 Score =  134 bits (333), Expect = 2e-30
 Identities = 108/346 (31%), Positives = 167/346 (48%), Gaps = 26/346 (7%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MKALIL GG+GTRLRPLT S  K L+  ANKP++ + IE +   G+ E+ + +    EQ+
Sbjct: 1   MKALILVGGFGTRLRPLTLSLPKPLVDFANKPMILHQIEALKAIGVDEVVLAINYEPEQL 60

Query: 61  IETVK-SVDWDA----NIEFIYQGEPKGLAHAILVARDYL----GNDDFVM---YLGDNI 108
           +   K S D +A     I    + EP G A  + +ARD L    G   FV+    + D  
Sbjct: 61  LVMSKFSNDVEATLGIKITCSQETEPLGTAGPLALARDKLVDGSGQPFFVLNSDVISDYP 120

Query: 109 LREGIVRHKEHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLAL 168
           L E I  H  H      +ASI++ +V  P ++GV  + E    ++R +EKPK    N   
Sbjct: 121 LEEMIAFHNAH----GGEASIMVTKVDEPSKYGVVVMEEATGRVERFVEKPKLFVGNKIN 176

Query: 169 VGIYFFRPIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLL 228
            GIY   P + + +  ++P+      I   I   I    K+    + G+W D G+P D +
Sbjct: 177 AGIYLLNPSVLDRI-ELRPT-----SIEKEIFPQIAEAEKLYAMLLPGFWMDIGQPRDYI 230

Query: 229 EANRLVLDEIERE--IKVETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIG 286
              RL LD + ++   K+ T   I+G V ++E A+I E  +I     IG   V+ +    
Sbjct: 231 TGLRLYLDSLRKKSPSKLATGPHILGNVLVDETAEIGEGCLIGPNVAIGPGCVVESGVRL 290

Query: 287 PYTSVGNNVVIEDTEVEDSIIMDGSVIIGAGRIIE--SIIGKEVRI 330
            + +V   V ++      S I+     +G    +E  SI+GK V +
Sbjct: 291 SHCTVMRGVHVKRYACISSSIIGWHSTVGQWARVENMSILGKNVYV 336


>sp|P37762|RFBA_NEIGO GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (DTDP-GLUCOSE SYNTHASE)
           (DTDP-GLUCOSE PYROPHOSPHORYLASE) >gi|628591|pir||S47046
           glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24)
           - Neisseria gonorrhoeae >gi|520897|emb|CAA83653.1|
           (Z32742) Glucose-1-phosphate thymidylyltransferase
           [Neisseria gonorrhoeae] >gi|1333794|emb|CAA79719.1|
           (Z21508) glucose-1-phosphate thymid transferase
           [Neisseria gonorrhoeae]
           Length = 288
           
 Score =  133 bits (332), Expect = 3e-30
 Identities = 78/238 (32%), Positives = 128/238 (53%), Gaps = 5/238 (2%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK +IL+GG GTRL P+T    KQL+PV +KP+++Y +  ++ AGI +I +I  P     
Sbjct: 1   MKGIILAGGSGTRLYPITRGVSKQLLPVYDKPMIYYPLSVLMLAGIRDILVITAPEDNAA 60

Query: 61  IETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNIL-REGIVRHK 117
            + +     D+   +++  Q  P GLA A ++  +++GN +  + LGDNI   +   +  
Sbjct: 61  FQRLLGDGSDFGIRLQYAVQPSPDGLAQAFIIGEEFIGNGNVCLILGDNIFYGQSFTQTL 120

Query: 118 EHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPI 177
           +      + A++    V +P++FGV E  E+   +  + EKP+ P S+ A+ G+YF    
Sbjct: 121 KQAAAKTHGATVFGYRVKDPERFGVVEFDENFNALS-IEEKPQQPKSDWAVTGLYFHDNR 179

Query: 178 IHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLV 234
             E  + +KPS R ELEI+D  +  +++G         G+ W DTG  E L EA   V
Sbjct: 180 AVEFAKQLKPSARGELEISDLNRMYLEDGSLSVQILGRGFAWLDTGTQESLHEAASFV 237


>emb|CAB05930.1| (Z83335) glucose-1-phosphate thymidylyltransferase [Streptococcus
           pneumoniae]
           Length = 285
           
 Score =  133 bits (331), Expect = 3e-30
 Identities = 81/236 (34%), Positives = 129/236 (54%), Gaps = 5/236 (2%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK +IL+GG GTRL PLT +  KQL+PV +KP+++Y +  ++ AGI +I II  P     
Sbjct: 1   MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLAGIRDILIISTPQDLHR 60

Query: 61  IETVKSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILR-EGIVRHKEH 119
            + +     +  I+  Y  +P      + +  +++ +D   + LGDNI    G+    + 
Sbjct: 61  FQELLQDGSEFGIKLSYAEQPS--TDGLAIGEEFISDDSVALILGDNIYHGPGLSTMLQK 118

Query: 120 FEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPIIH 179
             K +  A++   +V +P++FGV E   D   I  + EKP++P SN A+ G+YF+   + 
Sbjct: 119 AAKKEKGATVFGYQVKDPERFGVVEFDTDMNAIS-IEEKPEYPRSNYAVTGLYFYDNDVV 177

Query: 180 EAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLV 234
           E  + IKPS R ELEITD  +  +D G         G+ W +TG  E LLEA++ +
Sbjct: 178 EIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRGFAWLNTGTHESLLEASQYI 233


>pir||T01007 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) - Arabidopsis
           thaliana >gi|2642159|gb|AAB87126.1| (AC003000) putative
           GDP-mannose  pyrophosphorylase [Arabidopsis thaliana]
           >gi|3598958|gb|AAC78474.1| (AF076484) GDP-mannose
           pyrophosphorylase [Arabidopsis thaliana]
           >gi|4151925|gb|AAD04627.1| (AF108660) CYT1 protein
           [Arabidopsis thaliana]
           Length = 361
           
 Score =  133 bits (331), Expect = 3e-30
 Identities = 103/366 (28%), Positives = 170/366 (46%), Gaps = 45/366 (12%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MKALIL GG+GTRLRPLT S  K L+  ANKP++ + IE +   G+ E+ + +    E +
Sbjct: 1   MKALILVGGFGTRLRPLTLSFPKPLVDFANKPMILHQIEALKAVGVDEVVLAINYQPEVM 60

Query: 61  IETVKSVDWDANIEFI--YQGEPKGLAHAILVARDYL--GNDDFVMYLGDNILREGIVRH 116
           +  +K  +    I+     + EP G A  + +ARD L  G+ +    L  +++ E  ++ 
Sbjct: 61  LNFLKDFETKLEIKITCSQETEPLGTAGPLALARDKLLDGSGEPFFVLNSDVISEYPLKE 120

Query: 117 KEHFEKS-DYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFR 175
              F KS   +ASI++ +V  P ++GV  + E    +++ +EKPK    N    GIY   
Sbjct: 121 MLEFHKSHGGEASIMVTKVDEPSKYGVVVMEESTGRVEKFVEKPKLYVGNKINAGIYLLN 180

Query: 176 PIIHEAVRHIKPSWRNE-LEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLV 234
           P + + +     S   E      A Q L           + G+W D G+P D +   RL 
Sbjct: 181 PSVLDKIELRPTSIEKETFPKIAAAQGLYA-------MVLPGFWMDIGQPRDYITGLRLY 233

Query: 235 LDEIERE--IKVETRAKIIGRVKIEEGAKIDENTIIKGPAVIG----------------- 275
           LD + ++   K+ +   I+G V ++E A I E  +I     IG                 
Sbjct: 234 LDSLRKKSPAKLTSGPHIVGNVLVDETATIGEGCLIGPDVAIGPGCIVESGVRLSRCTVM 293

Query: 276 ------RNAVIRNAYIGPYTSVGN-------NVVIEDTEVEDSIIMDGSVIIGAGRIIES 322
                 ++A I ++ IG +++VG         ++ ED  V D I  +G V++    I  +
Sbjct: 294 RGVRIKKHACISSSIIGWHSTVGQWARIENMTILGEDVHVSDEIYSNGGVVLPHKEIKSN 353

Query: 323 IIGKEV 328
           I+  E+
Sbjct: 354 ILKPEI 359


>gb|AAA67589.1| (M87049) similar to Streptomyces griseus StrD protein [Escherichia
           coli]
           Length = 292
           
 Score =  132 bits (330), Expect = 4e-30
 Identities = 79/237 (33%), Positives = 126/237 (52%), Gaps = 4/237 (1%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK ++L+GG GTRL P+T    KQL+P+ +KP+++Y +  ++ AGI EI II  P  +  
Sbjct: 1   MKGIMLAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60

Query: 61  IETVKS--VDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKE 118
            + +     ++   +E+  Q  P GLA A ++   +L  +   + LGDNI        K 
Sbjct: 61  FQRLLGDVGEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPII 178
               +  +  +   +V +P++FG  E  ++ + I  L EKPK P SN A+ G+YF+   +
Sbjct: 121 RHVAARTEGPVFGYQVMDPERFGXVEFDDNFRAIS-LEEKPKQPKSNWAVTGLYFYDSKV 179

Query: 179 HEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLV 234
            E  + +KPS R ELEIT   Q  ++ G         G+ W DTG  + L+EA+  V
Sbjct: 180 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 236


>gb|AAC44072.1| (U51197) glucose-1-phosphate thymidylyltransferase [Sphingomonas
           sp. S88]
           Length = 292
           
 Score =  132 bits (329), Expect = 6e-30
 Identities = 90/283 (31%), Positives = 143/283 (49%), Gaps = 12/283 (4%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK +IL+GG GTRL P T S  KQL+PV +KP++FY +  ++  GI +I II  P    +
Sbjct: 1   MKGIILAGGSGTRLYPATLSISKQLLPVYDKPMIFYPLSVLMLTGIRDILIISTPRDLPM 60

Query: 61  IETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNIL---REGIVR 115
            + +      +  N+ +  Q  P GLA A ++  D++GND   + LGDNI    + G   
Sbjct: 61  FQALLGDGSAFGINLSYAEQPSPNGLAEAFIIGADFVGNDPSALILGDNIYHGEKMGERC 120

Query: 116 HKEHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFR 175
                + S   A++    V +P+++GV     +      + EKP +P SN A+ G+YF+ 
Sbjct: 121 QAAAAQASQGGANVFAYHVDDPERYGVVAFDPETGVATSVEEKPANPKSNWAITGLYFYD 180

Query: 176 PIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLV 234
             + +  + I+PS R ELEITD  +  ++ G         G+ W DTG  + L EA   V
Sbjct: 181 KDVVDIAKSIQPSARGELEITDVNRIYMERGDLHITRLGRGYAWLDTGTHDSLHEAGSFV 240

Query: 235 LDEIEREIKVETRAKIIGRVKIE-EGAKIDENTIIKGPAVIGR 276
                R ++  T  KI    +I  E   +  + ++K  A +G+
Sbjct: 241 -----RTLEHRTGVKIACPEEIAFESGWLGADDLLKRAAGLGK 278


>pir||T00103 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) -
           Actinobacillus actinomycetemcomitans
           >gi|3132255|dbj|BAA28132.1| (AB010415)
           glucose-1-phosphate-thymidylyltransferase
           [Actinobacillus actinomycetemcomitans]
           Length = 290
           
 Score =  132 bits (329), Expect = 6e-30
 Identities = 81/238 (34%), Positives = 125/238 (52%), Gaps = 5/238 (2%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK +IL+GG GTRL P+T    KQL+PV +KP+++Y +  ++ AG+ +I II  P   + 
Sbjct: 1   MKGIILAGGSGTRLYPITRGVSKQLLPVYDKPMIYYPLSVLMLAGVRDILIITTPEDNES 60

Query: 61  IETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNIL-REGIVRHK 117
            + +     ++  N+++  Q  P GLA A L+   ++  D   + LGDNI   +   +  
Sbjct: 61  FKRLLGDGSEFGVNLQYTIQPSPDGLAQAFLIGERFINGDSCCLVLGDNIFYGQNFTQML 120

Query: 118 EHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPI 177
           +      Y A++    V +P +FGV E  E+ K +  + EKP  P SN A+ G+YF+   
Sbjct: 121 QQAVARPYGATVFGYLVKDPGRFGVVEFDENFKAVS-IEEKPVQPKSNYAVTGLYFYDNR 179

Query: 178 IHEAVRHIKPSWRNELEITDAIQ-WLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLV 234
           + +  + +KPS R ELEIT   + +L D    V        W DTG  E L EA   V
Sbjct: 180 VVDFAKQVKPSARGELEITTLNEMYLKDGSLNVQLLGRGFAWLDTGTHESLHEAASFV 237


>dbj|BAA82533.1| (AB030032) glucose-1-phosphate thymidylyltransferase
           [Actinobacillus actinomycetemcomitans]
           Length = 290
           
 Score =  132 bits (329), Expect = 6e-30
 Identities = 84/244 (34%), Positives = 127/244 (51%), Gaps = 17/244 (6%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK +IL+GG GTRL P+T    KQL+PV +KP+++Y +  ++ AGI +I II  P   + 
Sbjct: 1   MKGIILAGGSGTRLYPITRGVSKQLLPVYDKPMIYYPLSVLMLAGIRDILIITTPEDNES 60

Query: 61  IETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKE 118
            + +     ++  N+++  Q  P GLA A L+   ++  D   + LGDNI       + +
Sbjct: 61  FKRLLGDGSNFGVNLQYAIQPSPDGLAQAFLIGEAFINGDSCCLVLGDNIF------YGQ 114

Query: 119 HFEK-------SDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGI 171
           HF +         Y A++    V +P +FGV E  E+ K +  + EKP  P SN A+ G+
Sbjct: 115 HFTQMLQRAVARPYGATVFGYLVKDPGRFGVVEFDENFKAVS-IEEKPAQPKSNYAVTGL 173

Query: 172 YFFRPIIHEAVRHIKPSWRNELEITDAIQ-WLIDNGYKVGWTKVTGWWKDTGKPEDLLEA 230
           YF+   + +  + +KPS R ELEIT   + +L D    V        W DTG  E L EA
Sbjct: 174 YFYDNRVVDFAKQVKPSARGELEITTLNEMYLKDGSLNVQLLGRGFAWLDTGTHESLHEA 233

Query: 231 NRLV 234
              V
Sbjct: 234 ASFV 237


>emb|CAB79775.1| (AL161577) GDP-mannose pyrophosphorylase like protein [Arabidopsis
           thaliana]
           Length = 351
           
 Score =  132 bits (329), Expect = 6e-30
 Identities = 97/322 (30%), Positives = 155/322 (48%), Gaps = 26/322 (8%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           +KALIL GG+GTRLRPLT S  K L+   NKP++ + IE +  AG+ E+ + +   + +V
Sbjct: 1   LKALILVGGFGTRLRPLTLSMPKPLVDFGNKPMILHQIEALKGAGVTEVVLAINHQQPEV 60

Query: 61  -IETVKSVD--WDANIEFIYQGEPKGLAHAILVARDYLGNDD---FVMYLGDNILREGIV 114
            +  VK  +   +  I F  + EP G A  + +ARD L ++    F +   D I    ++
Sbjct: 61  MLNFVKEYEKKLEIKITFSQETEPLGTAGPLALARDKLVDESGQPFFVLNSDVICEYPLL 120

Query: 115 RHKEHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFF 174
              E  + +  +ASI++ EV +P ++GV    E    ++  +EKPKH   N    GIY  
Sbjct: 121 EMIEFHKTNRAEASIMVTEVDDPSKYGVVVTEEGTARVESFVEKPKHFVGNKINAGIYLL 180

Query: 175 RPIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLV 234
            P + + +   + S   E      I   I +  K+    + G+W D G+P+D +   R+ 
Sbjct: 181 SPSVLDRIELRRTSIEKE------IFPKIASEKKLYAMVLPGFWMDIGQPKDYITGQRMY 234

Query: 235 LDEIEREIKVE--TRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVI------------ 280
           L+ +  +   E  T   IIG V + E A I E  +I    VIG   VI            
Sbjct: 235 LNSLREKTPQELATGDNIIGNVLVHESAVIGEGCLIGPDVVIGPGCVIDSGVRLFGCTVM 294

Query: 281 RNAYIGPYTSVGNNVVIEDTEV 302
           R  +I  +  + N++V  D+ V
Sbjct: 295 RGVWIKEHACISNSIVGWDSTV 316


>gb|AAK40653.1| Sugar phosphate nucleotydyl transferase [Sulfolobus solfataricus]
           Length = 361
           
 Score =  132 bits (328), Expect = 8e-30
 Identities = 104/353 (29%), Positives = 174/353 (48%), Gaps = 28/353 (7%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           + A++L+GGY TRLRPL+ ++ K L P+ NKP+L Y +E +I + + +I + +    +++
Sbjct: 2   VSAIVLAGGYATRLRPLSLTKPKALFPILNKPILGYILESLINSDVSDIYLSLRVMADKI 61

Query: 61  IETVKSVDWDANIEFIYQGEPKGLAHAI-LVARDYLGNDDFVMYLGDNILREGIVRHKEH 119
           I+ +K       ++   + EP G A  + L+++ Y  +DD ++  GD      I    + 
Sbjct: 62  IDYLKDTSMLDKVKIEVESEPLGDAGPLKLISQKYNLDDDVLVIYGDIYSEINIKSLLDF 121

Query: 120 FEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPIIH 179
           + K   DA ++  EV +P+++GV  L  +   +  LIEKPK P SNL   G+Y F+  + 
Sbjct: 122 YYKKSCDAVVVGTEVEDPRRYGV--LYTENDVLVELIEKPKKPISNLINGGVYIFKKDLF 179

Query: 180 EAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLDEIE 239
           + V    PS  ++    D +  L+     +   K  G W D G P+D L  N        
Sbjct: 180 KLVE--TPSSISK----DFLPKLL-RTKSISVYKYHGIWADIGVPDDYLRLN-------- 224

Query: 240 REIKVETRAKIIGRVKIEEGAKIDENTIIKGPAVIG-RNAVIRNAYIGPYTSVGNNVVI- 297
                E   +   +  I   AK+ E + +  P  IG +N +  +AYI   T +GN+V I 
Sbjct: 225 ----FEVLVQKYPKGYINSSAKVSEKSTLIPPYYIGSKNVIGEDAYITSNTILGNDVEIG 280

Query: 298 EDTEVEDSIIMDGSVIIGAGRIIESIIGKEVRIVRG----DGHPLGRRLIVGD 346
           + T + +SI+M+   +     I  SII  + +I R     DG  LG  +I  D
Sbjct: 281 KGTYISESILMNKVQVKEYTYISGSIIADKTKIGRWNHILDGSILGEEVITSD 333


>emb|CAB01949.1| (Z79692) ExpA7 [Sinorhizobium meliloti]
           Length = 293
           
 Score =  132 bits (328), Expect = 8e-30
 Identities = 90/282 (31%), Positives = 143/282 (49%), Gaps = 10/282 (3%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK +IL+GG GTRL P+T S  KQL+PV +KP+++Y +  ++ AGI EI +I  P    +
Sbjct: 1   MKGIILAGGRGTRLYPVTISVSKQLLPVHDKPMIYYPLGMLMLAGIREILVITMPRDRPL 60

Query: 61  IETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNIL-REGIVRHK 117
            E +      +   I +  Q EP GLA A ++ RD++GN    + LGDNI    G+    
Sbjct: 61  FEELLGDGSQFGLAISYAEQPEPNGLAEAFIIGRDFIGNSSVALILGDNIFYGAGLPELC 120

Query: 118 EHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPI 177
                    A+I    V +P+++GV     +    + + EKP+   S+ A+ G+YF+   
Sbjct: 121 SDAAARPSGATIFAYRVDDPERYGVVSFDGETGRAETIEEKPELARSSWAVTGLYFYENS 180

Query: 178 IHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLVLD 236
           + E    IKPS R ELEITD  +  ++ G         G+ W DTG  + L +A   V  
Sbjct: 181 VLEIASSIKPSARGELEITDVNRAYLERGDLHVCRLGRGYAWLDTGTHDSLHDAASFV-- 238

Query: 237 EIEREIKVETRAKIIGRVKIE-EGAKIDENTIIKGPAVIGRN 277
              R I+     KI+   +I  E   +  + +++   ++G+N
Sbjct: 239 ---RTIEHRQGVKIMCPEEIALELGYVSADQVLQRADLLGKN 277


>dbj|BAA94403.1| (AB041266) D-glucose-1-phosphate thymidylyltransferase
           [Actinobacillus actinomycetemcomitans]
           Length = 290
           
 Score =  132 bits (328), Expect = 8e-30
 Identities = 81/238 (34%), Positives = 125/238 (52%), Gaps = 5/238 (2%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK +IL+GG GTRL P+T    KQL+PV +KP+++Y +  ++ AG+ +I II  P   + 
Sbjct: 1   MKGIILAGGSGTRLYPITRGVSKQLLPVYDKPMIYYPLSVLMLAGVRDILIITTPEDNES 60

Query: 61  IETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNIL-REGIVRHK 117
            + +     ++  N+++  Q  P GLA A L+   ++  D   + LGDNI   +   +  
Sbjct: 61  FKRLLGDGSEFGVNLQYAIQPSPDGLAQAFLIGERFINGDSCCLVLGDNIFYGQNFTQML 120

Query: 118 EHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPI 177
           +      Y A++    V +P +FGV E  E+ K +  + EKP  P SN A+ G+YF+   
Sbjct: 121 QQAVARPYGATVFGYLVKDPGRFGVVEFDENFKAVS-IEEKPIQPKSNYAVTGLYFYDNR 179

Query: 178 IHEAVRHIKPSWRNELEITDAIQ-WLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLV 234
           + +  + +KPS R ELEIT   + +L D    V        W DTG  E L EA   V
Sbjct: 180 VVDFAKQVKPSARGELEITTLNEMYLKDGSLNVQLLGRGFAWLDTGTHESLHEAASFV 237


>dbj|BAA19634.1| (AB002668) glucose-1-phosphate-thymidylyltransferase
           [Actinobacillus actinomycetemcomitans]
           Length = 290
           
 Score =  131 bits (327), Expect = 1e-29
 Identities = 80/238 (33%), Positives = 124/238 (51%), Gaps = 5/238 (2%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK +IL+GG GTRL P+T    KQL+PV +KP+++Y +  ++ AG+ +I II  P   + 
Sbjct: 1   MKGIILAGGSGTRLYPITRGVSKQLLPVYDKPMIYYPLSVLMLAGVRDILIITTPEDNES 60

Query: 61  IETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNIL-REGIVRHK 117
            + +     ++  N+++  Q  P GLA A L+   ++  D   + LGDNI   +   +  
Sbjct: 61  FKRLLGDGSEFGVNLQYAIQPSPDGLAQAFLIGEGFINGDSCCLVLGDNIFYGQNFTQML 120

Query: 118 EHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPI 177
           +      Y A++    V +P +FGV E  E+ K +  + EKP  P SN A+ G+YF+   
Sbjct: 121 QQAVARPYGATVFGYLVKDPGRFGVVEFDENFKAVS-IEEKPAQPKSNYAVTGLYFYDNR 179

Query: 178 IHEAVRHIKPSWRNELEITDAIQ-WLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLV 234
           + +  + +KPS R ELEIT   + +L D    V        W DTG  E L E    V
Sbjct: 180 VVDFAKQVKPSARGELEITTLNEMYLKDGSLNVQLLGRGFAWLDTGTHESLHEGASFV 237


>pir||D75597 glucose-1-phosphate thymidylyltransferase - Deinococcus radiodurans
           (strain R1) >gi|6460561|gb|AAF12267.1|AE001862_93
           (AE001862) glucose-1-phosphate thymidylyltransferase
           [Deinococcus radiodurans]
           Length = 296
           
 Score =  131 bits (325), Expect = 2e-29
 Identities = 83/258 (32%), Positives = 136/258 (52%), Gaps = 8/258 (3%)

Query: 2   KALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQVI 61
           K +IL+GG GTRL P T +  KQL+P+ +KP+++Y +  ++  G+ EI II  P      
Sbjct: 6   KGIILAGGSGTRLYPATLAVSKQLLPIYDKPMIYYPLTTLMLGGMREILIISTPEDTPRF 65

Query: 62  ETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNIL-REGIVRHKE 118
           + +      W   +E+  Q +P+GLA A L+  D++      + LGDNI     +    +
Sbjct: 66  KQLLGDGSQWGIALEYAVQPKPEGLAQAFLIGEDFVQGHPSSLILGDNIFYGNDLSDLMQ 125

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPII 178
                +  A++   +V +P+++GV +    G+ +  + EKP  P S+ A+ G+YF+   +
Sbjct: 126 AANAKENGATVFAYQVRDPERYGVVDFDRSGRALS-IEEKPAQPKSDFAVTGLYFYDERV 184

Query: 179 HEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLVLDE 237
            E  R IKPS R ELEITD     ++ G         G+ W DTG  E +L+A+ L +  
Sbjct: 185 SEIARSIKPSPRGELEITDLNNVYLEEGALDVQLMRRGFAWLDTGTHESMLDAS-LFIQT 243

Query: 238 IERE--IKVETRAKIIGR 253
           IE+   +KV +  +I  R
Sbjct: 244 IEQRQGLKVASPEEIAWR 261


>emb|CAB88884.1| (AL353861) putative mannose-1-phosphate guanyltransferase
           [Streptomyces coelicolor A3(2)]
           Length = 831
           
 Score =  131 bits (325), Expect = 2e-29
 Identities = 105/367 (28%), Positives = 180/367 (48%), Gaps = 36/367 (9%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MKA++++GG GTRLRP+T S  K L+PV N+P++ + +  +   G++E  + V    + +
Sbjct: 1   MKAVVMAGGEGTRLRPMTSSMPKPLLPVVNRPIMEHVLRLLKRHGLNETVVTV----QFL 56

Query: 61  IETVKSVDWDA---NIEFIYQGE--PKGLAHAILVARDYLGNDDFVMYLGDNI----LRE 111
              VK+   D     +E  Y  E  P G A ++  A + L +D F++  GD +    L +
Sbjct: 57  ASLVKNYFGDGEELGMELTYANEEKPLGTAGSVKNAEEALKDDAFLVISGDALTDFDLTD 116

Query: 112 GIVRHKEHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPP--SNLALV 169
            I  HKE         ++ L  VPNP +FG+  + E+GK ++R +EKP      S+    
Sbjct: 117 LINFHKEKGSL----VTVCLTRVPNPLEFGITIVDEEGK-VERFLEKPTWGQVFSDTVNT 171

Query: 170 GIYFFRPIIHEAVRHIKP-SWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLL 228
           GIY   P +   V    P  W       D    L+  G  +      G+W+D G  E  +
Sbjct: 172 GIYVMEPEVFNYVDPDVPVDWSG-----DVFPQLMKEGKPIYGYVAEGYWEDVGTHESYV 226

Query: 229 EANRLVLDEIEREIKVETRA-KIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIR-NAYIG 286
           +A     D +ER++ V+    +I   V + EGA++  + +++GP  +G  A +   A I 
Sbjct: 227 KAQ---ADVLERKVDVDIDGFEISPGVWVAEGAEVHPDAVLRGPLYVGDYAKVEAGAEIR 283

Query: 287 PYTSVGNNVVIEDTEVEDSIIMDGSVIIGA-GRIIESIIGKEVRIVRG----DGHPLGRR 341
            +T +G+NVV++        ++  +V +G    +   ++GK   I+R     DG  +G  
Sbjct: 284 EHTVIGSNVVVKSGAFLHKAVVADNVYVGPHSNLRGCVVGKNTDIMRAARIEDGAVIGDE 343

Query: 342 LIVGDKS 348
            +VG++S
Sbjct: 344 CLVGEES 350


>pir||S30683 hypothetical protein o292 - Escherichia coli
           Length = 292
           
 Score =  130 bits (323), Expect = 3e-29
 Identities = 78/237 (32%), Positives = 125/237 (51%), Gaps = 4/237 (1%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK ++L+GG GTRL P+T    KQL+P+ +KP+++Y +  ++ AGI EI II  P  +  
Sbjct: 1   MKGIMLAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60

Query: 61  IETVKS--VDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKE 118
            + +     ++   +E+  Q  P GLA A ++   +L  +   + LGDNI        K 
Sbjct: 61  FQRLLGDVGEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPII 178
               +  +  +   +V +P++F   E  ++ + I  L EKPK P SN A+ G+YF+   +
Sbjct: 121 RHVAARTEGPVFGYQVMDPERFXXVEFDDNFRAIS-LEEKPKQPKSNWAVTGLYFYDSKV 179

Query: 179 HEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLV 234
            E  + +KPS R ELEIT   Q  ++ G         G+ W DTG  + L+EA+  V
Sbjct: 180 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 236


>pir||C69106 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) -
           Methanobacterium thermoautotrophicum
           >gi|2622922|gb|AAB86257.1| (AE000933)
           glucose-1-phosphate thymidylyltransferase
           [Methanobacterium thermoautotrophicum]
           Length = 292
           
 Score =  130 bits (323), Expect = 3e-29
 Identities = 83/241 (34%), Positives = 127/241 (52%), Gaps = 11/241 (4%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK ++L+GG GTRL P+T +  KQL+P+ +KP+++Y +  ++ AGI +I II  P    +
Sbjct: 1   MKGIVLAGGSGTRLYPITRAVSKQLLPIYDKPMIYYPLSVLMLAGIRDILIISTPRDLPL 60

Query: 61  IETVKSVDWDANIEFIY--QGEPKGLAHAILVARDYLGNDDFVMYLGDNILR----EGIV 114
              +        + F Y  Q EP+G+A A +V +D++G+    + LGDN+        I+
Sbjct: 61  YRDLLGDGSQFGVRFSYRVQEEPRGIADAFIVGKDFIGDSKVALVLGDNVFYGHRFSEIL 120

Query: 115 RHKEHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFF 174
           R     E     A I    V +P+ FGV E   +G+ I  + EKP  P SN  + G+YF+
Sbjct: 121 RRAASLEDG---AVIFGYYVRDPRPFGVVEFDSEGRVIS-IEEKPSRPKSNYVVPGLYFY 176

Query: 175 RPIIHEAVRHIKPSWRNELEITDAIQWLIDNG-YKVGWTKVTGWWKDTGKPEDLLEANRL 233
              + E  R I+PS R ELEIT   +  +  G  +V        W DTG  + LLEA+  
Sbjct: 177 DNQVVEIARRIEPSDRGELEITSVNEEYLRMGKLRVELMGRGMAWLDTGTHDGLLEASSF 236

Query: 234 V 234
           +
Sbjct: 237 I 237


>dbj|BAA84594.1| (AB032523) glucose-1-phosphate thymidyltransferase [Streptomyces
           avermitilis]
           Length = 299
           
 Score =  129 bits (321), Expect = 5e-29
 Identities = 82/241 (34%), Positives = 127/241 (52%), Gaps = 11/241 (4%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK ++L+GG G+RL PLT +  KQL+PV +KP+++Y +  ++  GI +I +I  P+    
Sbjct: 1   MKGIVLAGGTGSRLYPLTRALSKQLLPVYDKPMIYYPLSVLMLGGIKDILVISSPDH--- 57

Query: 61  IETVKSVDWDA-----NIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVR 115
           +E  + +  D      NI++  Q  P G+A A L+  D++G D   + LGDNI       
Sbjct: 58  LEQFRRLLGDGSRLGLNIDYAAQQRPGGIAEAFLIGADFIGQDQVSLVLGDNIFHGMGFS 117

Query: 116 HKEHFEKSDYDASILL-CEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFF 174
           H       D D  +L    V +P+++GV E+   GK +  + EKP  P SNLA+ G+Y +
Sbjct: 118 HLLRSHTRDVDGCVLFGYAVTDPERYGVGEVDASGKLLS-VEEKPTAPRSNLAITGLYLY 176

Query: 175 RPIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRL 233
              + E  R I+ S R ELEITD  +  +  G         G+ W D G  + L+ A + 
Sbjct: 177 DNDVIEVARGIRSSARGELEITDVNRAYLAEGRARLVDLGRGFTWLDAGTHDSLMHAGQY 236

Query: 234 V 234
           V
Sbjct: 237 V 237


>gb|AAF52089.1| (AE003605) CG1129 gene product [alt 1] [Drosophila melanogaster]
           >gi|10727176|gb|AAG22216.1| (AE003605) CG1129 gene
           product [alt 2] [Drosophila melanogaster]
           Length = 369
           
 Score =  127 bits (316), Expect = 2e-28
 Identities = 107/361 (29%), Positives = 178/361 (48%), Gaps = 43/361 (11%)

Query: 2   KALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQVI 61
           +ALIL GGYGTRLRPLT S  K L+  ANKP+L + +E +++AG  ++ + V    EQ+ 
Sbjct: 12  RALILVGGYGTRLRPLTLSTPKPLVEFANKPILLHQLEALVDAGCRQVILAVSYRAEQME 71

Query: 62  ETVKSVDWDANIEFIY--QGEPKGLAHAILVARDYL--GNDDFVMYLGDNI----LREGI 113
           + +K       +E I+  + EP G A  + +A+  L   ++ F +   D I     ++ +
Sbjct: 72  KELKVEAKKLGVELIFSHETEPLGTAGPLALAKTILAASSEPFFVLNSDVICDFPFKQLV 131

Query: 114 VRHKEHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYF 173
             H  H +    + +I++ +V  P ++GV    E+G  IK  IEKP+   SN    GIY 
Sbjct: 132 QFHCNHGK----EGTIVVTKVEEPSKYGVVLYDENG-CIKNFIEKPQEFVSNKINAGIYI 186

Query: 174 FRPIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRL 233
           F P + + +  +KP+      I   +   +    ++    +TG+W D G+P+D L    L
Sbjct: 187 FNPSVLDRI-EVKPT-----SIEKEVFPEMTQQQELYAMDLTGFWMDIGQPKDFLTGMCL 240

Query: 234 VLDEI--EREIKVETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSV 291
            L  +  ++  K+ T   ++G V ++  AKI E                    IGP  ++
Sbjct: 241 YLSSLRQKQSPKLYTGPGVVGNVLVDPTAKIGE-----------------GCRIGPNVTI 283

Query: 292 GNNVVIED-TEVEDSIIMDGSVIIGAGRIIESIIGKEV---RIVRGDG-HPLGRRLIVGD 346
           G +VVIED   ++ S I+ G+++     +   I+G      R VR +G   LG  +IV D
Sbjct: 284 GPDVVIEDGVCIKRSTILKGAIVRSHSWLDSCIVGWRSTVGRWVRIEGITVLGEDVIVKD 343

Query: 347 K 347
           +
Sbjct: 344 E 344


>pir||B71146 probable glucose-1 phosphate transferase - Pyrococcus horikoshii
           >gi|3256772|dbj|BAA29455.1| (AP000002) 327aa long
           hypothetical glucose-1 phosphate transferase [Pyrococcus
           horikoshii]
           Length = 327
           
 Score =  127 bits (316), Expect = 2e-28
 Identities = 100/352 (28%), Positives = 169/352 (47%), Gaps = 43/352 (12%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK LI++GGY TRL P+T    K L+P+ NK +L Y +E V E    ++ + +  N+   
Sbjct: 1   MKVLIMAGGYATRLWPITKDNPKALLPLGNKTILEYILEKVREL---DVDVYISTNR-FF 56

Query: 61  IETVKSVDWDANIE-FIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKEH 119
            E  +  D +  +E  +++ E  G   A+  A + LG DD+++  GDN+    +    ++
Sbjct: 57  AEKFRKYDVELIVEDTVHEEEKLGTIAAMRNALNILGEDDYLIVAGDNVFSFSLKDFVDN 116

Query: 120 FEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFF-RPII 178
           F      A   + +    +++GV  L +D   +    EKP +P S L   G+Y F R ++
Sbjct: 117 FSGKTLIAVYDVGDFELAKRYGVVVLEKD--RVIDFEEKPANPKSTLISTGVYLFPRDVM 174

Query: 179 HEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLDE- 237
                +++    N+      +QWL+  G ++   +  G+W D G  +  LEA + +L E 
Sbjct: 175 KLLNEYLEDG--NKDSPGYFLQWLLKRGEEIRAYRFDGYWYDIGSADSYLEAMKTLLKES 232

Query: 238 IEREIKVETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSVGNNVVI 297
              EI++   AKII  V I++G KI           +GR      + IGPY  +G   +I
Sbjct: 233 YIEEIQISPYAKIIPPVVIKKGTKI-----------MGR------SIIGPYAYIGEECII 275

Query: 298 EDTEVEDSIIMDGSVI---------------IGAGRIIESIIGKEVRIVRGD 334
           E++++ DSII   +VI               I    + +S++G   +I RGD
Sbjct: 276 ENSDISDSIIFPRTVIRNSTIWRSIIDEKCEIRNLELRKSLVGGHAKIQRGD 327


>pir||G70527 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) -
           Mycobacterium tuberculosis >gi|2326953|gb|AAB66657.1|
           (U55242) alpha-D-glucose-1-phosphate
           thymidylyltransferase [Mycobacterium tuberculosis]
           >gi|3261803|emb|CAB09613.1| (Z96800) rmlA [Mycobacterium
           tuberculosis]
           Length = 288
           
 Score =  127 bits (316), Expect = 2e-28
 Identities = 81/234 (34%), Positives = 122/234 (51%), Gaps = 6/234 (2%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           M+ +IL+GG GTRL P+T    KQL+PV +KP+++Y +  ++ AGI +I +I  P+    
Sbjct: 1   MRGIILAGGSGTRLYPITMGISKQLLPVYDKPMIYYPLTTLMMAGIRDIQLITTPHDAPG 60

Query: 61  IETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNIL-REGIVRHK 117
              +         NI +  Q +P GLA A ++  +++G D   + LGDNI    G+    
Sbjct: 61  FHRLLGDGAHLGVNISYATQDQPDGLAQAFVIGANHIGADSVALVLGDNIFYGPGLGTSL 120

Query: 118 EHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPI 177
           + F+ S    +I    V NP  +GV E   +G  +  L EKP  P SN A+ G+YF+   
Sbjct: 121 KRFQ-SISGGAIFAYWVANPSAYGVVEFGAEGMALS-LEEKPVTPKSNYAVPGLYFYDND 178

Query: 178 IHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEA 230
           + E  R +K S R E EIT+  Q  ++ G         G  W DTG  + LL+A
Sbjct: 179 VIEIARGLKKSARGEYEITEVNQVYLNQGRLAVEVLARGTAWLDTGTFDSLLDA 232


>pir||T41209 mannose-1-phosphate guanyltransferase - fission yeast
           (Schizosaccharomyces pombe) >gi|3581924|emb|CAA20770.1|
           (AL031538) mannose-1-phosphate guanyltransferase
           [Schizosaccharomyces pombe]
           Length = 363
           
 Score =  126 bits (314), Expect = 3e-28
 Identities = 102/349 (29%), Positives = 168/349 (47%), Gaps = 38/349 (10%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MKALIL GG+GTRLRPLT +  K L+   NKP++ + +E +  AG+ +I + V    E +
Sbjct: 1   MKALILVGGFGTRLRPLTLTLPKPLVEFGNKPMILHQVEALAAAGVTDIVLAVNYRPEIM 60

Query: 61  IETVKSV--DWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMY-LGDNILREGIVRHK 117
           +E +K    +++ NI F  + EP G A  + +ARD L  D    + L  +++ E      
Sbjct: 61  VEALKKYEKEYNVNITFSVENEPLGTAGPLALARDILAKDHSPFFVLNSDVICEYPFADL 120

Query: 118 EHFEKS-DYDASILLCEVPNPQQFG-VAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFR 175
             F K+   + +I++ +V  P ++G V         I+R +EKP    SN    GIY   
Sbjct: 121 AAFHKAHGAEGTIVVTKVEEPSKYGVVVHYPNSESLIERFVEKPVEFVSNRINGGIYILN 180

Query: 176 PIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVL 235
           P + + +     S   E E+  A+     N  ++    + G+W D G+P+D L    L L
Sbjct: 181 PSVLDRIEPRPTS--IEKEVFPAMV----NDKQLHSFDLEGYWMDVGQPKDYLTGTCLYL 234

Query: 236 DEIER---EIKVETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSVG 292
             + +   EI     + IIG V I+  A I +N  I GP          N  IGP  ++G
Sbjct: 235 SSLRKHKPEILAPASSNIIGNVLIDPSATIGKNCKI-GP----------NVVIGPNVTIG 283

Query: 293 NNV------VIEDTEVEDSIIMDGSVI-----IGAGRIIE--SIIGKEV 328
           + V      +++ + V D   +  S++     +G+   +E  S++G +V
Sbjct: 284 DGVRLQRCAILKSSRVRDHAWVKSSIVGWNSTLGSWSRLENVSVLGDDV 332


>pir||T32900 hypothetical protein C42C1.5 - Caenorhabditis elegans
           >gi|2804432|gb|AAB97547.1| (AF043695) similar to S.
           cerevisiae mannose-1-phosphate guanyltransferase
           (GB:U24437) [Caenorhabditis elegans]
           Length = 373
           
 Score =  125 bits (312), Expect = 6e-28
 Identities = 94/344 (27%), Positives = 164/344 (47%), Gaps = 29/344 (8%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MKALIL GGYGTRLRPLT +Q K L+  ANKP++ + +E + E G+  + + V    EQ+
Sbjct: 9   MKALILVGGYGTRLRPLTLTQPKPLVEFANKPMMLHQMEALAEVGVDTVVLAVSYRAEQL 68

Query: 61  IE--TVKSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKE 118
            +  TV +      + F  + EP G A  + +AR +L  D     L  +++ +   +   
Sbjct: 69  EQEMTVHADRLGVKLIFSLEEEPLGTAGPLALARKHLEGDAPFFVLNSDVICDFPFKQMV 128

Query: 119 HFEKS-DYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPI 177
            F K+   + +I + +V  P ++GV    +D   I   +EKP+    N    G+Y F   
Sbjct: 129 EFHKNHGKEGTIAVTKVEEPSKYGVVVFDQDKGKIDDFVEKPQEYVGNKINAGLYIFSSK 188

Query: 178 IHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVL-- 235
           I + +  +KP+   E EI   + +   +G    +  + G+W D G+P+D L+   L L  
Sbjct: 189 ILDRI-PLKPT-SIEKEIFPEMAF---SGNLYAFV-LPGFWMDVGQPKDFLKGMSLFLNH 242

Query: 236 ------DEIEREIKVETRAKIIGRVKIEEGAKIDENTIIKGPAVIG------------RN 277
                 D++E    +   A I G V ++  A + EN +I    VIG             +
Sbjct: 243 CHTTKSDKLETGSNIHPTATIRGNVMVDPSATVGENCVIGPDVVIGPRVKIEGGVRILHS 302

Query: 278 AVIRNAYIGPYTSVGNNVVIEDTEVEDSIIMDGSVIIGAGRIIE 321
            ++ ++ IG Y+ V  ++V     +   + ++   +IG   +++
Sbjct: 303 TILSDSSIGNYSWVSGSIVGRKCHIGSWVRIENICVIGDDVVVK 346


>pir||G75164 mannose-1-phosphate guanyltransferase PAB0317 - Pyrococcus abyssi
           (strain Orsay) >gi|5457908|emb|CAB49398.1| (AJ248284)
           MANNOSE-1-PHOSPHATE GUANYLTRANSFERASE [Pyrococcus
           abyssi]
           Length = 361
           
 Score =  125 bits (310), Expect = 1e-27
 Identities = 101/355 (28%), Positives = 168/355 (46%), Gaps = 30/355 (8%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           M+A++L+GG GTRL PLT  + K +IP  NKP++ Y + +++E G+ EI ++VG  KE++
Sbjct: 1   MQAVLLAGGMGTRLLPLTIYRPKPMIPFFNKPLMEYMVNNLVEVGVDEIIVLVGYLKEKI 60

Query: 61  IETV-KSVDWDANIEFIYQGEPK-GLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKE 118
           IE      ++   I++      K G A A+  A  ++    F++   D +         E
Sbjct: 61  IEHFGDGKEFGVEIKYSNGENVKFGTAGALKRAEKFI-EGTFIVASSDVLTNLDFKSLLE 119

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPK--HPPSNLALVGIYFFRP 176
              K    A++ L +V +P  +GVA L ++GK I    EKP+    PSNL   GIY F P
Sbjct: 120 FHAKKGGIATMALTKVEDPSPYGVAVLDDEGK-ILYFKEKPRREEAPSNLVNAGIYVFEP 178

Query: 177 IIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLD 236
            I + +   KP   +     +    +++ G  +       +W D G+P   L+A      
Sbjct: 179 EILDLIPKGKPFDFS----LNLFPKMLEEGIPIYGFPFDEYWNDVGRPSTYLQA------ 228

Query: 237 EIEREIKVETRAKIIGRVKIEE--GAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSVGNN 294
                    T    +G++K+ +    ++  N    G    G   ++RN  +  +  +G+N
Sbjct: 229 ---------TEDVFLGKLKLPQISVGRLKGNVERGGSLFTGSRCILRNPKVSGFAVLGDN 279

Query: 295 VVI-EDTEVEDSIIMDGSVIIGAGRIIESIIGKEVRIVRGDGHPLGRRLIVGDKS 348
           V I  D ++E S+I     I     I E+IIG+ V I  G G  +    ++GD S
Sbjct: 280 VEIGRDVKIERSVIFSNVTIEDGAEIREAIIGENVYI--GKGVTIEPGSVIGDNS 332


>gb|AAA69677.1| (U24437) mannose-1-phosphate guanyltransferase [Saccharomyces
           cerevisiae]
           Length = 361
           
 Score =  123 bits (307), Expect = 2e-27
 Identities = 99/341 (29%), Positives = 166/341 (48%), Gaps = 19/341 (5%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK LIL GGYGTRLRPLT +  K L+   N+P++ + IE +  AG+ +I + V    E +
Sbjct: 1   MKGLILVGGYGTRLRPLTLTVPKPLVEFGNRPMILHQIEALANAGVTDIALAVNYRPEVM 60

Query: 61  IETVKSV--DWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMY-LGDNILREGIVRHK 117
           +ET+K    ++  NI F  + EP G A  + +A D L  D+   + L  +++ E   +  
Sbjct: 61  VETLKKYEKEYGVNITFSVETEPLGTAGPLKLAEDVLKKDNSPFFVLNSDVICEYPFKEL 120

Query: 118 EHFEKS-DYDASILLCEVPNPQQFGVAELSEDGKT---IKRLIEKPKHPPSNLALVGIYF 173
             F K+     +I+  +V  P ++GV  +  D  T   I R +EKPK    N    G+Y 
Sbjct: 121 ADFHKAHGGKGTIVATKVDEPSKYGV--IVHDIATPNLIDRFVEKPKEFVGNRINAGLYI 178

Query: 174 FRPIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRL 233
             P + + +  +KP+    +E  +    L++      +  + G+W D G+P+D L    L
Sbjct: 179 LNPEVIDLI-EMKPT---SIE-KETFPILVEEKQLYSF-DLEGFWMDVGQPKDFLSGTVL 232

Query: 234 VLDEIERE--IKVETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSV 291
            L+ + +    K+ T A I+G   I+  AKI     I    VIG N  I +      + V
Sbjct: 233 YLNSLAKRQPKKLATGANIVGNALIDPTAKISSTAKIGPDVVIGPNVTIGDGVRITRSVV 292

Query: 292 GNNVVIEDTEVEDSIIMDGSVIIGAGRIIE--SIIGKEVRI 330
             N  I++  +  S I+  +  +G    +E  +++G +V +
Sbjct: 293 LCNSTIKNHSLVKSTIVGWNSTVGQWCRLEGVTVLGDDVEV 333


>gi|6320148 mannose-1-phosphate guanyltransferase, GDP-mannose
           pyrophosphorylase; Psa1p [Saccharomyces cerevisiae]
           >gi|1709086|sp|P41940|MPG1_YEAST MANNOSE-1-PHOSPHATE
           GUANYLTRANSFERASE (ATP-MANNOSE-1-PHOSPHATE
           GUANYLYLTRANSFERASE) (NDP-HEXOSE PYROPHOSPHORYLASE)
           >gi|2132332|pir||S67590 mannose-1-phosphate
           guanylyltransferase (EC 2.7.7.13) - yeast (Saccharomyces
           cerevisiae) >gi|1292898|gb|AAC49289.1| (U19608) Psa1p
           [Saccharomyces cerevisiae] >gi|1431053|emb|CAA98617.1|
           (Z74103) ORF YDL055c [Saccharomyces cerevisiae]
           Length = 361
           
 Score =  122 bits (304), Expect = 5e-27
 Identities = 99/341 (29%), Positives = 166/341 (48%), Gaps = 19/341 (5%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK LIL GGYGTRLRPLT +  K L+   N+P++ + IE +  AG+ +I + V    E +
Sbjct: 1   MKGLILVGGYGTRLRPLTLTVPKPLVEFGNRPMILHQIEALANAGVTDIVLAVNYRPEVM 60

Query: 61  IETVKSV--DWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMY-LGDNILREGIVRHK 117
           +ET+K    ++  NI F  + EP G A  + +A D L  D+   + L  +++ E   +  
Sbjct: 61  VETLKKYEKEYGVNITFSVETEPLGTAGPLKLAEDVLKKDNSPFFVLNSDVICEYPFKEL 120

Query: 118 EHFEKS-DYDASILLCEVPNPQQFGVAELSEDGKT---IKRLIEKPKHPPSNLALVGIYF 173
             F K+     +I+  +V  P ++GV  +  D  T   I R +EKPK    N    G+Y 
Sbjct: 121 ADFHKAHGGKGTIVATKVDEPSKYGV--IVHDIATPNLIDRFVEKPKEFVGNRINAGLYI 178

Query: 174 FRPIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRL 233
             P + + +  +KP+    +E  +    L++      +  + G+W D G+P+D L    L
Sbjct: 179 LNPEVIDLI-EMKPT---SIE-KETFPILVEEKQLYSF-DLEGFWMDVGQPKDFLSGTVL 232

Query: 234 VLDEIERE--IKVETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSV 291
            L+ + +    K+ T A I+G   I+  AKI     I    VIG N  I +      + V
Sbjct: 233 YLNSLAKRQPKKLATGANIVGNALIDPTAKISSTAKIGPDVVIGPNVTIGDGVRITRSVV 292

Query: 292 GNNVVIEDTEVEDSIIMDGSVIIGAGRIIE--SIIGKEVRI 330
             N  I++  +  S I+  +  +G    +E  +++G +V +
Sbjct: 293 LCNSTIKNHSLVKSTIVGWNSTVGQWCRLEGVTVLGDDVEV 333


>pir||T42371 probable mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) -
           fission yeast (Schizosaccharomyces pombe)
           >gi|1749464|dbj|BAA13790.1| (D89128) similar to
           Saccharomyces cerevisiae putative NDP-hexose
           pyrophosphopylase, SWISS-PROT Accession Number P41940
           [Schizosaccharomyces pombe]
           Length = 363
           
 Score =  122 bits (303), Expect = 6e-27
 Identities = 100/349 (28%), Positives = 167/349 (47%), Gaps = 38/349 (10%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MKALIL GG+GTRLRPLT +  K L+   NKP++ + +E +  AG+ +I + V    E +
Sbjct: 1   MKALILVGGFGTRLRPLTLTLPKPLVEFGNKPMILHQVEALAAAGVTDIVLAVNYRPEIM 60

Query: 61  IETVKSV--DWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMY-LGDNILREGIVRHK 117
           +E +K    +++ NI F  + EP G A  + +ARD L  D    + L  +++ E      
Sbjct: 61  VEALKKYEKEYNVNITFSVENEPLGTAGPLALARDILAKDHSPFFVLNSDVICEYPFADL 120

Query: 118 EHFEKS-DYDASILLCEVPNPQQFG-VAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFR 175
             F K+   + +I++ +V  P ++G V         I+R +EKP    SN     +Y   
Sbjct: 121 AAFHKAHGAEGTIVVTKVEEPSKYGVVVHYPNSESLIERFVEKPVEFVSNRINGVLYILN 180

Query: 176 PIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVL 235
           P + + +     S   E E+  A+     N  ++    + G+W D G+P+D L    L L
Sbjct: 181 PSVLDRIEPRPTS--IEKEVFPAMV----NDKQLHSFDLEGYWMDVGQPKDYLTGTCLYL 234

Query: 236 DEIER---EIKVETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSVG 292
             + +   EI     + IIG V I+  A I +N  I GP          N  IGP  ++G
Sbjct: 235 SSLRKHKPEILAPASSNIIGNVLIDPSATIGKNCKI-GP----------NVVIGPNVTIG 283

Query: 293 NNV------VIEDTEVEDSIIMDGSVI-----IGAGRIIE--SIIGKEV 328
           + V      +++ + V D   +  S++     +G+   +E  S++G +V
Sbjct: 284 DGVRLQRCAILKSSRVRDHAWVKSSIVGWNSTLGSWSRLENVSVLGDDV 332


>dbj|BAA77382.1| (AB020570) GDP-mannose pyrophosphorylase [Candida glabrata]
           Length = 361
           
 Score =  122 bits (302), Expect = 8e-27
 Identities = 97/339 (28%), Positives = 168/339 (48%), Gaps = 27/339 (7%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK LIL GGYGTRLRPLT +  K L+   N+P++ + IE +  AG+ +I + V    E +
Sbjct: 1   MKGLILVGGYGTRLRPLTLTVPKPLVEFGNRPMILHQIEALANAGVTDIVLAVNCRPEVM 60

Query: 61  IETVKSV--DWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMY-LGDNILREGIVRHK 117
           +ET++    ++  +I F  + EP G A  + +A   L  D+   + L  +++ E   +  
Sbjct: 61  VETLQKYEKEYGVSITFSVETEPLGTAGPLKLAEKVLKKDNSPFFVLNSDVICEYPFKEL 120

Query: 118 EHFEKS-DYDASILLCEVPNPQQFGVAELSEDGKT---IKRLIEKPKHPPSNLALVGIYF 173
             F K+     +I+  +V  P ++GV  +  D  T   I R +EKPK    N    G+Y 
Sbjct: 121 ADFHKAHGGKGTIVATKVDEPSKYGV--IVHDIATPNLIDRFVEKPKEFVGNRINAGLYI 178

Query: 174 FRPIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRL 233
             P + + +  +KP+    +E T+    L++      +  + G+W D G+P+D L    L
Sbjct: 179 LNPEVIDLI-EMKPT---SIE-TETFPILVEQKSLYSF-DLEGFWMDVGQPKDFLSGTVL 232

Query: 234 VLDEIERE--IKVETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSV 291
            L+ + ++   K+     I+G V ++  AKI  +  +    VIG N       IG    +
Sbjct: 233 YLNSVSKKNPEKLTKGDNIVGNVMVDPSAKIAASAKVGPDVVIGPNVT-----IGEGVRI 287

Query: 292 GNNVVIEDTEVEDSIIMDGSVIIGAGRIIESIIGKEVRI 330
             +VV+ D+ ++D  ++  S I+G     +S +GK  R+
Sbjct: 288 TRSVVLSDSSIQDHSLVK-STIVG----WKSTVGKWCRL 321


>pir||C71177 probable mannose-1-phosphate guanyltransferase - Pyrococcus
           horikoshii >gi|3258127|dbj|BAA30810.1| (AP000007) 361aa
           long hypothetical mannose-1-phosphate guanyltransferase
           [Pyrococcus horikoshii]
           Length = 361
           
 Score =  121 bits (300), Expect = 1e-26
 Identities = 110/359 (30%), Positives = 174/359 (47%), Gaps = 38/359 (10%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           M+A++L+GG GTRL PLT  + K +IP  NKP++ Y + ++I  G+ EI ++VG  KE++
Sbjct: 1   MQAVLLAGGKGTRLLPLTVYRPKPMIPFFNKPLMEYMLMNLIGIGVEEIIVLVGYLKEKI 60

Query: 61  IETVKSVDWDANIEFIY-QGE--PKGLAHAILVARDYLGNDDFVMYLGD---NILREGIV 114
           IE     D    +E  Y  GE    G A A+  A  ++ +D F++   D   N+  +  +
Sbjct: 61  IEYFGRGD-KFGVEIKYSNGENIKLGTAGALKKAEKFI-DDTFIVASSDVLTNLSFDSFI 118

Query: 115 RHKEHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPK--HPPSNLALVGIY 172
           R   H EK    A++ L +V +P  +GVA L  + + I    EKPK    PSNL   GIY
Sbjct: 119 RF--HREKGGI-ATMALTKVEDPTPYGVAVLDNENR-ILYFKEKPKREEAPSNLVNAGIY 174

Query: 173 FFRPIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANR 232
            F P I + +    P  +      D    +++ G  +       +W D G+P   L+A  
Sbjct: 175 IFEPEILDLI----PRGKAFDFSLDLFPKMLEEGIPIYGFPFDEYWNDVGRPSTYLQA-- 228

Query: 233 LVLDEIEREIKVETRAKIIGRVKIEE-GAKIDENTIIKGPAVI-GRNAVIRNAYIGPYTS 290
                        T    +G++++ +     D+  I +G ++  G   +IRN  I  +  
Sbjct: 229 -------------TEDVFLGKLRLPQINVGRDKGNIERGGSLFTGSKCLIRNPKIVGFAV 275

Query: 291 VGNNVVI-EDTEVEDSIIMDGSVIIGAGRIIESIIGKEVRIVRGDGHPLGRRLIVGDKS 348
           +GNNV +  D ++E S+I     I     I E+IIG+ V I RG     G   ++GD S
Sbjct: 276 LGNNVKVGRDVKIERSVIFSNVTIEDEVEIREAIIGENVYIGRGAVIEPGS--VIGDNS 332


>emb|CAA77210.1| (Y18523) dTDP-glucose synthase [Actinoplanes sp. 50/110]
           Length = 303
           
 Score =  121 bits (300), Expect = 1e-26
 Identities = 72/233 (30%), Positives = 114/233 (48%), Gaps = 4/233 (1%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           M+ ++L+GG G+RLRP+T++  KQL+PV +KP+++Y +  ++  GI EI +I    +   
Sbjct: 1   MRGILLAGGTGSRLRPVTWAVSKQLMPVYDKPMIYYPLATLVSCGIREILVITTETEAAQ 60

Query: 61  IETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKE 118
            + +      W   +EF  Q  P G+A A L+  ++L      + LGDN+L     R   
Sbjct: 61  FQRLLGDGSQWGLRLEFAVQQRPGGIAEAFLIGEEFLAGGPVALMLGDNLLHGVDFRPCV 120

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPII 178
              +      +    V +P  +GV E    G+ +  + EKP  P S  A+ G Y +   +
Sbjct: 121 QRARETAGGHVFGVAVADPSAYGVVEFDAAGRVLS-IEEKPVRPRSPYAVPGFYLYDADV 179

Query: 179 HEAVRHIKPSWRNELEITDAIQWLIDNG-YKVGWTKVTGWWKDTGKPEDLLEA 230
            E  R ++PS R ELEIT+  Q  +  G   V        W DTG   D + A
Sbjct: 180 VETARSLRPSARGELEITEVNQAYLRRGALSVTLLGRGAVWLDTGTLADCMRA 232


>sp|P55257|RFBA_YEREN GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (DTDP-GLUCOSE SYNTHASE)
           (DTDP-GLUCOSE PYROPHOSPHORYLASE) >gi|479759|pir||S35294
           probable glucose-1-phosphate thymidylyltransferase (EC
           2.7.7.24) - Yersinia enterocolitica
           >gi|48585|emb|CAA79347.1| (Z18920) WbbS [Yersinia
           enterocolitica]
           Length = 289
           
 Score =  120 bits (298), Expect = 3e-26
 Identities = 76/244 (31%), Positives = 129/244 (52%), Gaps = 6/244 (2%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK ++L+GG GTRL P+T    KQL+PV +KP+++Y I  ++ AGI +I II  P     
Sbjct: 1   MKGIVLAGGAGTRLHPITRGVSKQLLPVYDKPMIYYPISVLMLAGIQDILIISTPEDLPS 60

Query: 61  IETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNI-LREGIVRHK 117
            + +      +   +++  Q  P GLA A ++  +++  +   + LGDNI   +   +  
Sbjct: 61  FKRLLGDGSQFGIRLQYAKQPSPDGLAQAFIIGEEFIAGERCALVLGDNIYFGQSFGKQL 120

Query: 118 EHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPI 177
                 +  A++   +V + ++FGV E  E+   +  + EKP+ P S+ A+ G+YF+   
Sbjct: 121 REVASRNDGATVFGYQVVDAERFGVIEFDENFNALS-IEEKPQKPKSDWAVTGLYFYDKD 179

Query: 178 IHEAVRHIKPSWRNELEITDAIQWLIDNG-YKVGWTKVTGWWKDTGKPEDLLEANRLVLD 236
           + E  + IKPS R ELEIT   +  +  G  +V        W DTG  + L++A+ L + 
Sbjct: 180 VVEMAKEIKPSERGELEITTLNEMYLAKGKLRVELLGRGFAWLDTGTHDSLIDAS-LFIH 238

Query: 237 EIER 240
            IE+
Sbjct: 239 TIEK 242


>gb|AAF67515.1|AF170880_22 (AF170880) NovV [Streptomyces spheroides]
           Length = 297
           
 Score =  120 bits (298), Expect = 3e-26
 Identities = 76/248 (30%), Positives = 128/248 (50%), Gaps = 12/248 (4%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           M+ ++L+GG G+RL P+T +  KQLIPV +KP+++Y +  ++ AG+ EI +I  P+ ++ 
Sbjct: 1   MRGILLAGGTGSRLWPVTRAISKQLIPVFDKPMIYYPLTTLMMAGVREILVITRPDDQRQ 60

Query: 61  IETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKE 118
              +          +E+  Q  P+G+A A ++  +++G+    + LGDNI     +  + 
Sbjct: 61  FRHLLGDGSQLGLRLEYAVQERPEGIAQAFVLGAEFIGDQSVALVLGDNIFHGAGLGTRL 120

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPII 178
                   A I    V +P+ +GV E  E G+ +  + EKP  P S  A+ G+YF+   +
Sbjct: 121 RQYNDPAGARIFAYVVADPKAYGVVEFDEAGRAVS-IEEKPARPKSRYAVPGLYFYDNRV 179

Query: 179 HEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-----WKDTGKPEDLLEANRL 233
            + V  + PS R ELEIT   +  +    K G  +VT       W DTG    L++A+  
Sbjct: 180 LDVVHGLVPSRRGELEITAVNETYL----KWGQLRVTTLDRGTAWLDTGTFASLVQASEY 235

Query: 234 VLDEIERE 241
           V    ER+
Sbjct: 236 VRVVEERQ 243


>gb|AAG29804.1| (AF235050) dTDP-glucose synthase; glucose-1-phosphate
           thymidylyltransferase [Streptomyces rishiriensis]
           Length = 296
           
 Score =  119 bits (296), Expect = 4e-26
 Identities = 82/272 (30%), Positives = 134/272 (49%), Gaps = 19/272 (6%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           M+ ++L+GG G+RL P+T +  KQLIPV +KP+++Y +  ++ AGI EI +I  P  ++ 
Sbjct: 1   MRGILLAGGTGSRLWPVTRAVSKQLIPVFDKPMIYYPLTTLMMAGIREILVITRPEDQRQ 60

Query: 61  IETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKE 118
              +          +E+  Q +P+G+A A ++  D++G+    + LGDNI     +  + 
Sbjct: 61  FRHLLGDGSQLGLCLEYAVQEKPEGIAQAFVLGADFIGDQSVALVLGDNIFHGAGLGTRL 120

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPII 178
                     I    V +P+ + V E  E G  +  + EKP  P S  A+ G+YF+   +
Sbjct: 121 RQYSDPAGGRIFAYVVADPRAYAVVEFDEAGTAVS-IEEKPASPKSRYAVPGLYFYDNRV 179

Query: 179 HEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVT-----GWWKDTGKPEDLLEANRL 233
            E  R + PS R ELEIT   +  +    K G  +VT       W DTG    L++A+  
Sbjct: 180 LEVARDLMPSQRGELEITAVNETYL----KWGQLRVTTLDRGAAWLDTGTFTSLVQASEY 235

Query: 234 VLDEIERE-------IKVETRAKIIGRVKIEE 258
           V    ER+        +V  R  +IG  ++ E
Sbjct: 236 VRVVEERQGLKIGCVEEVAWRCGLIGNDQLRE 267


>pir||S49053 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) tylA1
           [validated] - Streptomyces fradiae
           >gi|473599|gb|AAA21343.1| (U08223) dTDP-glucose synthase
           [Streptomyces fradiae]
           Length = 303
           
 Score =  117 bits (291), Expect = 2e-25
 Identities = 81/246 (32%), Positives = 122/246 (48%), Gaps = 23/246 (9%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK +IL+GG GTRLRPLT +  KQL+PV +KP+++Y +  ++ AGI EI II   +   +
Sbjct: 9   MKGIILAGGSGTRLRPLTGTLSKQLLPVYDKPMIYYPLSVLMLAGIREIQIISSKDHLDL 68

Query: 61  IETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILR-------- 110
             ++  +      +I +  Q EP+G+A A L+   ++G DD  + LGDN+          
Sbjct: 69  FRSLLGEGDRLGLSISYAEQREPRGIAEAFLIGARHIGGDDAALILGDNVFHGPGFSSVL 128

Query: 111 EGIVRHKEHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHP--PSNLAL 168
            G V   +  E   Y        V +  ++GV E+   G+ +  L EKP+ P  P    L
Sbjct: 129 TGTVARLDGCELFGY-------PVKDAHRYGVGEIDSGGRLLS-LEEKPRRPLEPGRHRL 180

Query: 169 VGIYFFRPIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLL 228
              Y +   + E  R I PS R ELEITD  +  ++ G           W D G  + LL
Sbjct: 181 ---YLYTNDVVEIARTISPSARGELEITDVNKVYLEQGRAAHGAGAVVAWLDMGTHDSLL 237

Query: 229 EANRLV 234
           +A + V
Sbjct: 238 QAGQYV 243


>gb|AAD23920.1|AF083467_4 (AF083467) glucose-1-phosphate thymidyl transferase [Neisseria
           meningitidis]
           Length = 298
           
 Score =  117 bits (290), Expect = 2e-25
 Identities = 60/176 (34%), Positives = 103/176 (58%), Gaps = 4/176 (2%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK +IL+GG GTRL P+T    KQL+PV +KP+++Y +  ++ AGI +I +I  P     
Sbjct: 14  MKGIILAGGSGTRLYPITRGVSKQLLPVYDKPMIYYPLSVLMLAGIRDILVITAPEDNAS 73

Query: 61  IETV--KSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNIL-REGIVRHK 117
            + +     D+  +I +  Q  P GLA A ++  +++GND+  + LGDNI   +   +  
Sbjct: 74  FKRLLGDGSDFGISISYAVQPSPDGLAQAFIIGEEFIGNDNVCLVLGDNIFYGQSFTQTL 133

Query: 118 EHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYF 173
           +      + A++   +V NP++FGV E +E+ + +  + EKP+ P S+ A+ G+YF
Sbjct: 134 KQAAAQTHGATVFAYQVKNPERFGVVEFNENFRAVS-IEEKPQRPKSDWAVTGLYF 188


>gb|AAD45556.1|U70376_21 (U70376) SpcK [Streptomyces flavopersicus]
           Length = 303
           
 Score =  116 bits (289), Expect = 3e-25
 Identities = 76/244 (31%), Positives = 124/244 (50%), Gaps = 4/244 (1%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           M+ ++L+GG G+RL P+T +  KQL+ + +KP+++Y +  ++ AGI EI II     +  
Sbjct: 1   MRGILLAGGTGSRLWPVTRAVSKQLMQIFDKPMIYYPLSTLMMAGIREILIITTREDQPG 60

Query: 61  IETVKSVDWDANIEFIY--QGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKE 118
              +        IE  Y  Q  P+G+A A L+  D++G +   + LGDNI        + 
Sbjct: 61  FRRLLGDGSHLGIEITYAVQECPEGIAQAFLIGSDFIGAETVALALGDNIFHGQAFGRRL 120

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPII 178
              ++   A +L   V +P  +GV E+SE G  +  + EKP+ P S  A VG+ F+   +
Sbjct: 121 RAHRNLSGARVLAYPVADPSAYGVVEISETGAAVS-VEEKPEKPKSRYATVGLSFYDHRV 179

Query: 179 HEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLVLDE 237
            +  R ++PS R ELEIT   +  +  G         G  W DTG    +++A+  V   
Sbjct: 180 VDIARGLRPSERGELEITAVNEEYLRRGELAVTVLDRGTAWLDTGTFSAMVQASEYVRVM 239

Query: 238 IERE 241
            ER+
Sbjct: 240 EERQ 243


>pir||H82325 UTP--glucose-1-phosphate uridylyltransferase VC0395 [imported] -
           Vibrio cholerae (group O1 strain N16961)
           >gi|9654816|gb|AAF93568.1| (AE004128)
           UTP--glucose-1-phosphate uridylyltransferase [Vibrio
           cholerae]
           Length = 291
           
 Score =  116 bits (289), Expect = 3e-25
 Identities = 81/282 (28%), Positives = 137/282 (47%), Gaps = 35/282 (12%)

Query: 2   KALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIV-------- 53
           K L  + GYGTR  P T S  K+++PV NKP++ Y +++ I+AGI  + I+         
Sbjct: 5   KCLFPAAGYGTRFLPATKSMPKEMMPVVNKPLIEYGVDEAIQAGITGMCIVTGRGKHSIM 64

Query: 54  --------------GPNKEQVIETVKSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDD 99
                         G NKE+++  ++ +   AN  FI Q E KGL HAIL  ++ +G++ 
Sbjct: 65  DHFDMNYELEHQIRGTNKEELLGDIRKIIESANFTFIRQREMKGLGHAILTGKELVGDEP 124

Query: 100 FVMYLGDNIL---REGIVRHKEHFEKSDYDASILLCEVPNPQ--QFGVAE---LSEDGKT 151
           F + L D++     +G++       K    + + + EVP  +  ++GV     + +D   
Sbjct: 125 FAVVLADDLCVNEEQGVLAQMVALYKQFRCSIVAVQEVPENETHKYGVIAGEMIKDDLFR 184

Query: 152 IKRLIEKPK--HPPSNLALVGIYFFRPIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKV 209
           +  ++EKP+    PSNLA++G Y   P I + +   +P    E++ITDA+      G  +
Sbjct: 185 VDNMVEKPEPGTAPSNLAIIGRYILTPDIFDLIEQTEPGKGGEIQITDALLKQAKAGCVL 244

Query: 210 GWTKVTGWWKDTGKPEDLLEANRLVLDEI--EREIKVETRAK 249
            + K  G   D G  E  +EA     + +  + + KVE   K
Sbjct: 245 AY-KFKGKRFDCGSVEGYIEATNFCYENMYKKNDQKVELAKK 285


>gi|11431484 GDP-mannose pyrophosphorylase B [Homo sapiens]
           Length = 360
           
 Score =  116 bits (288), Expect = 4e-25
 Identities = 102/363 (28%), Positives = 172/363 (47%), Gaps = 45/363 (12%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MKALIL GGYGTRLRPLT S  K L+   NKP+L + +E +  AG+  + + V    + +
Sbjct: 1   MKALILVGGYGTRLRPLTLSTPKPLVDFCNKPILLHQVEALAAAGVDHVILAVSYMSQVL 60

Query: 61  IETVKSVD--WDANIEFIYQGEPKGLAHAILVARDYLGN--DDFVMYLGDNI----LREG 112
            + +K+ +      I   ++ EP G A  + +ARD L    D F +   D I     +  
Sbjct: 61  EKEMKAQEQRLGIRISMSHEEEPLGTAGPLALARDLLSETADPFFVLNSDVICDFPFQAM 120

Query: 113 IVRHKEHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIY 172
           +  H+ H +    + SIL+ +V  P ++GV     D   I R +EKP+   SN    G+Y
Sbjct: 121 VQFHRHHGQ----EGSILVTKVEEPSKYGVVVCEADTGRIHRFVEKPQVFVSNKINAGMY 176

Query: 173 FFRPIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANR 232
              P + + ++ ++P+      I   +  ++    ++   ++ G+W D G+P+D L    
Sbjct: 177 ILSPAVLQRIQ-LQPT-----SIEKEVFPIMAKEGQLYAMELQGFWMDIGQPKDFLTGMC 230

Query: 233 LVLDEIERE--IKVETRAKIIGRVKIEEGAKIDEN-----TIIKGPAV-------IGRNA 278
           L L  + ++   ++ +   I+G V ++  A+I +N      +  GP V       I R  
Sbjct: 231 LFLQSLRQKQPERLCSGPGIVGNVLVDPSARIGQNCSIGPNVSLGPGVVVEDGVCIRRCT 290

Query: 279 VIRNAYIGPYT-----------SVGNNVVIEDTEV--EDSIIMDGSVIIGAGRIIESIIG 325
           V+R+A I  ++            VG  V +E+  V  ED I+ D   + GA  +    IG
Sbjct: 291 VLRDARIRSHSWLESCIVGWRCRVGQWVRMENVTVLGEDVIVNDELYLNGASVLPHKSIG 350

Query: 326 KEV 328
           + V
Sbjct: 351 ESV 353


>pir||A83394 UTP--glucose-1-phosphate uridylyltransferase PA2023 [imported] -
           Pseudomonas aeruginosa (strain PAO1)
           >gi|9948027|gb|AAG05411.1|AE004628_9 (AE004628)
           UTP--glucose-1-phosphate uridylyltransferase
           [Pseudomonas aeruginosa]
           Length = 279
           
 Score =  116 bits (287), Expect = 5e-25
 Identities = 76/270 (28%), Positives = 129/270 (47%), Gaps = 34/270 (12%)

Query: 2   KALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVG------- 54
           K L  + GYGTR  P T +  K+++PV NKP++ YA+E+ +EAG+ EIGI+ G       
Sbjct: 4   KCLFPAAGYGTRFLPATKAMPKEMLPVVNKPLIQYAVEEALEAGLSEIGIVTGRGKRSLE 63

Query: 55  ---------------PNKEQVIETVKSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDD 99
                           +KE+ +  ++ +  +    +  Q E KGL HAIL  R  +G++ 
Sbjct: 64  DHFDISYELEHQIRNTDKEKYLVGIRRLIDECTFAYTRQVEMKGLGHAILTGRPLIGDEP 123

Query: 100 FVMYLGD----NILREGIVRHKEHFEKSDYDASILLCEVP--NPQQFGVAE---LSEDGK 150
           F + L D    N+  + +++           + + + EVP     ++GV     + +D  
Sbjct: 124 FAVVLADDLCLNLEGDSVLKQMVKLYNQFRCSIVAIQEVPPEETNKYGVIAGEMIRDDIF 183

Query: 151 TIKRLIEKPK--HPPSNLALVGIYFFRPIIHEAVRHIKPSWRNELEITDAIQWLIDNGYK 208
            +  ++EKPK    PSNLA++G Y   P I + +   +P    E++ITDA+     +G  
Sbjct: 184 RVNTMVEKPKPEEAPSNLAIIGRYILTPDIFDLIEQTEPGKGGEIQITDALMKQAQDGCV 243

Query: 209 VGWTKVTGWWKDTGKPEDLLEANRLVLDEI 238
           + + K  G   D G  E  +EA     + +
Sbjct: 244 LAY-KFKGKRFDCGSAEGYIEATNFCYENL 272


>emb|CAB58292.1| (AL121851) mannose-1-phosphate guanyltransferase [Leishmania major]
           Length = 379
           
 Score =  115 bits (286), Expect = 6e-25
 Identities = 99/350 (28%), Positives = 166/350 (47%), Gaps = 45/350 (12%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           M+A+IL GG+GTRLRPLT +  K L+P  NKP++ + IE +   G+ E+ + V    E +
Sbjct: 9   MRAVILVGGFGTRLRPLTLTTPKPLVPFCNKPMIIHQIEALKAVGVTEVILAVAYRPEAM 68

Query: 61  IETVKSVDWDANIEFIY--QGEPKGLAHAILVARDYLGNDDFVMY-LGDNI-----LREG 112
            E +        + F++  + EP G A  + +ARD L  DD   + L  ++     ++E 
Sbjct: 69  KEQMDEWSRKLGVLFVFSVEEEPLGTAGPLALARDILMQDDKPFFVLNSDVTCPFPMQEL 128

Query: 113 IVRHKEHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIY 172
           +  HK H      + +I++ +V   +++GV   S     I+R +EKP     +    GIY
Sbjct: 129 LDFHKAH----GGEGTIMVSQVTQWEKYGVVVYSPQNYQIERFVEKPSSFLGDRINAGIY 184

Query: 173 FFRPIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPED------ 226
            F   I + +   + S   E+  + A +       ++    + G+W D G+P+D      
Sbjct: 185 IFNKSILDRIPPCRTSIEKEIFPSMAAEG------QLYAFNLEGFWMDIGQPKDYILGMT 238

Query: 227 -----LLEANRLVLDEIEREIKVETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIR 281
                L+ +NR    E E+     T+ +  GR  +   + ID +      A IG  AV  
Sbjct: 239 KYIPFLVHSNR----ETEKLHTEATKHQRGGRFTVIGASLIDPS------AKIGDGAV-- 286

Query: 282 NAYIGPYTSVGNNVVI-EDTEVEDSIIMDGSVIIGAGRIIESIIGKEVRI 330
              IGPY S+G N VI E   ++++ I++ S +     +  SI+G   RI
Sbjct: 287 ---IGPYASIGANCVIGESCRIDNAAILENSKVGKGSMVSRSIVGWNNRI 333


>gb|AAD31796.1|AF128272_1 (AF128272) TDP-glucose synthase [Streptomyces spectabilis]
           Length = 291
           
 Score =  115 bits (286), Expect = 6e-25
 Identities = 80/246 (32%), Positives = 123/246 (49%), Gaps = 8/246 (3%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           M+ +IL+GG G+RL P+T +  KQL+PV +KP+++Y +  ++ AGI +I +I     E  
Sbjct: 1   MRGIILAGGTGSRLWPVTQAVSKQLMPVFDKPMVYYPLSTLMLAGIRDILVITTREDEID 60

Query: 61  IETVKSVDWDANIEFIY--QGEPKGLAHAILVARDYLGNDDFVMYLGDNIL--REGIVRH 116
              +        +   Y  Q  P G+A A L+  D++G +   + LGDNI   R   V  
Sbjct: 61  FRRLLGDGSHLGLRLTYRTQDRPGGIAEAFLIGADFIGGEPVALILGDNIFHGRSFGVHV 120

Query: 117 KEHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRP 176
           +EH   +     I    V +P  +GV E+ EDG T   + EKP  P S  A VG+YF+  
Sbjct: 121 REH--TAPDGGRIFAYPVADPTAYGVVEIGEDG-TALSIEEKPAKPKSRYAAVGLYFYDE 177

Query: 177 IIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRLVL 235
            + +    ++PS R ELEIT   +  +  G         G  W DTG    +++A+  V 
Sbjct: 178 HVVDIAAGLRPSERGELEITGVNEEYLRRGALSVTVLDRGTAWLDTGTFTAMVQASEYVR 237

Query: 236 DEIERE 241
              ER+
Sbjct: 238 VIEERQ 243


>gi|7019397 GDP-mannose pyrophosphorylase B [Homo sapiens]
           >gi|5052351|gb|AAD38516.1|AF135421_1 (AF135421)
           GDP-mannose pyrophosphorylase B [Homo sapiens]
           Length = 360
           
 Score =  115 bits (286), Expect = 6e-25
 Identities = 102/363 (28%), Positives = 171/363 (47%), Gaps = 45/363 (12%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MKALIL GGYGTRLRPLT S  K L+   NKP+L + +E +  AG+  + + V    + +
Sbjct: 1   MKALILVGGYGTRLRPLTLSTPKPLVDFCNKPILLHQVEALAAAGVDHVILAVSYMSQVL 60

Query: 61  IETVKSVD--WDANIEFIYQGEPKGLAHAILVARDYLGN--DDFVMYLGDNI----LREG 112
            + +K+ +      I   ++ EP G A  + +ARD L    D F +   D I     +  
Sbjct: 61  EKEMKAQEQRLGIRISMSHEEEPLGTAGPLALARDLLSETADPFFVLNSDVICDFPFQAM 120

Query: 113 IVRHKEHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIY 172
           +  H+ H +    + SIL+ +V  P ++GV     D   I R +EKP+   SN    G+Y
Sbjct: 121 VQFHRHHGQ----EGSILVTKVEEPSKYGVVVCEADTGRIHRFVEKPQVFVSNKINAGMY 176

Query: 173 FFRPIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANR 232
              P +   ++ ++P+      I   +  ++    ++   ++ G+W D G+P+D L    
Sbjct: 177 ILSPAVLRRIQ-LQPT-----SIEKEVFPIMAKEGQLYAMELQGFWMDIGQPKDFLTGMC 230

Query: 233 LVLDEIERE--IKVETRAKIIGRVKIEEGAKIDEN-----TIIKGPAV-------IGRNA 278
           L L  + ++   ++ +   I+G V ++  A+I +N      +  GP V       I R  
Sbjct: 231 LFLQSLRQKQPERLCSGPGIVGNVLVDPSARIGQNCSIGPNVSLGPGVVVEDGVCIRRCT 290

Query: 279 VIRNAYIGPYT-----------SVGNNVVIEDTEV--EDSIIMDGSVIIGAGRIIESIIG 325
           V+R+A I  ++            VG  V +E+  V  ED I+ D   + GA  +    IG
Sbjct: 291 VLRDARIRSHSWLESCIVGWRCRVGQWVRMENVTVLGEDVIVNDELYLNGASVLPHKSIG 350

Query: 326 KEV 328
           + V
Sbjct: 351 ESV 353


>dbj|BAB14882.1| (AK024319) unnamed protein product [Homo sapiens]
           Length = 387
           
 Score =  115 bits (284), Expect = 1e-24
 Identities = 88/309 (28%), Positives = 148/309 (47%), Gaps = 37/309 (11%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MKALIL GGYGTRLRPLT S  K L+   NKP+L + +E +  AG+  + + V    + +
Sbjct: 1   MKALILVGGYGTRLRPLTLSTPKPLVDFCNKPILLHQVEALAAAGVDHVILAVSYMSQVL 60

Query: 61  IETVKSVD--WDANIEFIYQGEPKGLAHAILVARDYLGN--DDFVMYLGDNI----LREG 112
            + +K+ +      I   ++ EP G A  + +ARD L    D F +   D I     +  
Sbjct: 61  EKEMKAQEQRLGIRISMSHEEEPLGTAGPLALARDLLSETADPFFVLNSDVICDFPFQAM 120

Query: 113 IVRHKEHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIY 172
           +  H+ H +    + SIL+ +V  P ++GV     D   I R +EKP+   SN    G+Y
Sbjct: 121 VQFHRHHGQ----EGSILVTKVEEPSKYGVVVCEADTGRIHRFVEKPQVFVSNKINAGMY 176

Query: 173 FFRPIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANR 232
              P +   ++ ++P+      I   +  ++    ++   ++ G+W D G+P+D L    
Sbjct: 177 ILSPAVLRRIQ-LQPT-----SIEKEVFPIMAKEGQLYAMELQGFWMDIGQPKDFLTGMC 230

Query: 233 LVLDEIERE--IKVETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTS 290
           L L  + ++   ++ +   I+G V ++  A+I +                 N  IGP  S
Sbjct: 231 LFLQSLRQKQPERLCSGPGIVGNVLVDPSARIGQ-----------------NCSIGPNVS 273

Query: 291 VGNNVVIED 299
           +G  VV+ED
Sbjct: 274 LGPGVVVED 282


>gb|AAC64911.1| (AF030299) putative GDP-mannose pyrophosphorylase [Candida
           albicans]
           Length = 362
           
 Score =  113 bits (280), Expect = 3e-24
 Identities = 93/339 (27%), Positives = 161/339 (47%), Gaps = 32/339 (9%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK LIL GGYGTRLRPLT +  K L+   N+P++ + IE +  AG+ +I + V    E +
Sbjct: 1   MKGLILVGGYGTRLRPLTLTLPKPLVEFGNRPMILHQIEALAAAGVTDIVLAVNYRPEVM 60

Query: 61  IETVKSV--DWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMY-LGDNILREGIVRHK 117
           + T+K    ++  +I F  + EP G A  + +A + L  DD   + L  +++ +   +  
Sbjct: 61  VSTLKKYEEEYGVSITFSVEEEPLGTAGPLKLAEEVLKKDDSPFFVLNSDVICDYPFKEL 120

Query: 118 EHFEKSDYDA-SILLCEVPNPQQFGVAELSED-GKTIKRLIEKPKHPPSNLALVGIYFFR 175
             F K+   A +I+  +V  P ++GV     D    I R +EKP     N    G+Y   
Sbjct: 121 ADFHKAHGAAGTIVATKVDEPSKYGVIVHDRDTPNLIDRFVEKPVEFVGNRINAGLYILN 180

Query: 176 PIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVL 235
           P + + +  ++P+    +E  D    L++      +  + G+W D G+P+D L    L L
Sbjct: 181 PSVIDLI-EMRPT---SIE-KDPFPILVEQKQLYSF-DLEGYWMDVGQPKDFLSGTCLYL 234

Query: 236 DEIEREIKVE-TRAKII--GRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSVG 292
             + ++   +  + K +  G V I+  AKI                   +A IGP  ++G
Sbjct: 235 TSLSKKHPEKLCKEKYVHGGNVLIDPTAKIHP-----------------SALIGPNVTIG 277

Query: 293 NNVVI-EDTEVEDSIIMDGSVIIGAGRIIESIIGKEVRI 330
            NVV+ E   ++ S+++  S +     +  +I+G   RI
Sbjct: 278 PNVVVGEGARIQRSVLLANSQVKDHAWVKSTIVGWNSRI 316


>dbj|BAA34807.1| (AB020596) GDP-mannose pyrophosphorylase [Candida albicans]
           Length = 362
           
 Score =  113 bits (279), Expect = 4e-24
 Identities = 92/339 (27%), Positives = 156/339 (45%), Gaps = 32/339 (9%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK LIL GGYGTRLRPLT +  K L+   N+P++ + IE +  AG+ +I + V    E +
Sbjct: 1   MKGLILVGGYGTRLRPLTLTLPKPLVEFGNRPMILHQIEALAAAGVTDIVLAVNYRPEVM 60

Query: 61  IETVKSV--DWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMY-LGDNILREGIVRHK 117
           + T+K    ++  +I F  + EP G A  + +A + L  DD   + L  +++ +   +  
Sbjct: 61  VSTLKKYEEEYGVSITFSVEEEPLGTAGPLKLAEEVLKKDDSPFFVLNSDVICDYPFKEL 120

Query: 118 EHFEKSDYDA-SILLCEVPNPQQFGVAELSED-GKTIKRLIEKPKHPPSNLALVGIYFFR 175
             F K+   A +I+  +V  P ++GV     D    I R +EKP     N    G+Y   
Sbjct: 121 ADFHKAHGAAGTIVATKVDEPSKYGVIVHDRDTPNLIDRFVEKPVEFVGNRINAGLYILN 180

Query: 176 PIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVL 235
           P + + +     S   E         L++      +  + G+W D G+P+D L    L L
Sbjct: 181 PSVIDLIEMRPTSIEKE-----TFPILVEQKQLYSF-DLEGYWMDVGQPKDFLSGTCLYL 234

Query: 236 DEIEREIKVE-TRAKII--GRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSVG 292
             + ++   +  + K +  G V I+  AKI                   +A IGP  ++G
Sbjct: 235 TSLSKKHPEKLCKEKYVHGGNVLIDPTAKIHP-----------------SALIGPNVTIG 277

Query: 293 NNVVI-EDTEVEDSIIMDGSVIIGAGRIIESIIGKEVRI 330
            NVV+ E   ++ S+++  S +     +  +I+G   RI
Sbjct: 278 PNVVVGEGARIQRSVLLANSQVKDHAWVKSTIVGWNSRI 316


>gb|AAC39498.1| (U89991) mannose-1-phosphate guanylyltransferase [Hypocrea
           jecorina]
           Length = 364
           
 Score =  113 bits (279), Expect = 4e-24
 Identities = 94/339 (27%), Positives = 161/339 (46%), Gaps = 40/339 (11%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK LIL GG+GTRLRPLT +  K L+   NKP++ + IE ++ AG+ +I + V    E +
Sbjct: 1   MKGLILVGGFGTRLRPLTLTLPKPLVEFCNKPMIVHQIEALVAAGVTDIVLAVNYRPEIM 60

Query: 61  IETVKSVD--WDANIEFIYQGEPKGLAHAILVARDYLGNDD---FVM---YLGDNILREG 112
            + +   +  ++ NIEF  + EP   A  + +A   LG DD   FV+    + D   +E 
Sbjct: 61  EKFLAEYEEKYNINIEFSVESEPLDTAGPLKLAERILGKDDSPFFVLNSDVICDYPFKEL 120

Query: 113 IVRHKEHFEKSDYDASILLCEVPNPQQFG-VAELSEDGKTIKRLIEKPKHPPSNLALVGI 171
           +  HK H +    + +I++ +V  P ++G V         I R +EKP     N    G+
Sbjct: 121 LEFHKAHGD----EGTIVVTKVEEPSKYGVVVHKPNHPSRIDRFVEKPVEFVGNRINAGM 176

Query: 172 YFFRPIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEAN 231
           Y F P + + +  ++P+    +E       + DN  ++    + G+W D G+P+D L   
Sbjct: 177 YIFNPSVLKRI-ELRPT---SIEKETFPAMVADN--QLHSFDLEGFWMDVGQPKDFLSGT 230

Query: 232 RLVLDEI----EREIKVETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGP 287
            L L  +     +E+   T   + G            N +I   A IG     +N  IGP
Sbjct: 231 CLYLSSLTKKGSKELTPPTEPYVHG-----------GNVMIHPSAKIG-----KNCRIGP 274

Query: 288 YTSVGNNVVIED-TEVEDSIIMDGSVIIGAGRIIESIIG 325
             ++G +VV+ D   ++  +++ GS +     +  +I+G
Sbjct: 275 NVTIGPDVVVGDGVRLQRCVLLKGSKVKDHAWVKSTIVG 313


>gb|AAC64912.1| (AF030300) putative GDP-mannose pyrophosphorylase [Candida
           albicans]
           Length = 362
           
 Score =  113 bits (279), Expect = 4e-24
 Identities = 89/327 (27%), Positives = 159/327 (48%), Gaps = 19/327 (5%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK LIL GGYGTRLRPLT +  K L+   N+P++ + IE +  AG+ +I + V    E +
Sbjct: 1   MKGLILVGGYGTRLRPLTLTLPKPLVEFGNRPMILHQIEALAAAGVTDIVLAVNYRPEVM 60

Query: 61  IETVKSV--DWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMY-LGDNILREGIVRHK 117
           + T+K    ++  +I F  + EP G A  + +A + L  DD   + L  +++ +   +  
Sbjct: 61  VSTLKKYEEEYGVSITFSVEEEPLGTAGPLKLAEEVLKKDDSPFFVLNSDVICDYPFKEL 120

Query: 118 EHFEKSDYDA-SILLCEVPNPQQFGVAELSED-GKTIKRLIEKPKHPPSNLALVGIYFFR 175
             F K+   A +I+  +V  P ++GV     D    I R +EKP     N    G+Y   
Sbjct: 121 ADFHKAHGAAGTIVATKVDEPSKYGVIVHDRDTPNLIDRFVEKPVEFVGNRINAGLYILN 180

Query: 176 PIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVL 235
           P + + +  ++P+    +E  D    L++      +  + G+W D G+P+D L    L L
Sbjct: 181 PSVIDLI-EMRPT---SIE-KDPFPILVEQKQLYSF-DLEGYWMDVGQPKDFLSGTCLYL 234

Query: 236 DEIEREIKVE-TRAKII--GRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSVG 292
             + ++   +  + K +  G V I+  AKI  + +I     IG N V     +G    + 
Sbjct: 235 TSLSKKHPEKLCKEKYVHGGNVLIDPTAKIHPSALIGPNVTIGPNVV-----VGEGARIR 289

Query: 293 NNVVIEDTEVEDSIIMDGSVIIGAGRI 319
            +V++ +++V+D   +  +++    RI
Sbjct: 290 RSVLLANSQVKDHAWVKSTIVGWNSRI 316


>pir||A75096 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) PAB0771
           [similarity] - Pyrococcus abyssi (strain Orsay)
           >gi|5458582|emb|CAB50070.1| (AJ248286)
           UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE (EC
           2.7.7.9) (UDP-GLUCOSE PYROPHOSPHORYLASE) (UDPGP)
           (ALPHA-D-GLUCOSYL-1-PHOSPHATE URIDYLYLTRANSFERASE)
           (URIDINE DIPHOSPHOGLUCOSE PYROPHOSPHORYLASE).
           [Pyrococcus abyssi]
           Length = 291
           
 Score =  113 bits (279), Expect = 4e-24
 Identities = 78/275 (28%), Positives = 138/275 (49%), Gaps = 35/275 (12%)

Query: 2   KALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKE--- 58
           KA+I + G GTR+ P+T S  K+++P+ ++PV+ Y +E+ ++AGI +I II G  K    
Sbjct: 4   KAVIPAAGLGTRMLPITKSMPKEMLPIVDRPVIHYVVEEAVKAGIEDILIITGKGKRAIE 63

Query: 59  -------------------QVIETVKSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDD 99
                              + +  V+ +    +I ++ Q +P GL  AIL A  ++  + 
Sbjct: 64  DYFDRSFELEYYLKERGKLEALREVEEIGEMVDIYYVRQKKPLGLGDAILYAEKHVNGEP 123

Query: 100 FVMYLGDNILREGIVRHKEHFEKSDYDASILLCEVPNPQQ----FGVAE---LSEDGKTI 152
           F + LGD+I+       K+  E ++   + ++     P++    +G+ E   +  D   I
Sbjct: 124 FAVLLGDDIIISKKPAIKQLIEVAERKNTPVIGVESVPRELVSRYGIIEGELIENDLYRI 183

Query: 153 KRLIEK--PKHPPSNLALVGIYFFRPIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVG 210
           KRL+EK  PK  PSN+A++G Y   P I + +R   P    E+++TDA+Q L+ N  ++ 
Sbjct: 184 KRLVEKPSPKEAPSNIAIIGRYILIPEIFDILRETPPGRDGEIQLTDALQILL-NKNEIL 242

Query: 211 WTKVTGWWKDTGKPEDLLEAN---RLVLDEIEREI 242
             ++ G   D G     + AN    L  +E+  E+
Sbjct: 243 AKRIEGERYDIGSKFGFVMANLKLSLRREELRNEV 277


>gb|AAF60300.1|AF234177_1 (AF234177) GDP-mannose pyrophosphorylase [Pichia angusta]
           Length = 364
           
 Score =  111 bits (275), Expect = 1e-23
 Identities = 94/342 (27%), Positives = 161/342 (46%), Gaps = 18/342 (5%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MK LIL GGYGTRLRPLT S  K L+   N+P++ + IE +  AG  +I + V    E +
Sbjct: 1   MKGLILVGGYGTRLRPLTLSLPKPLVEFGNRPMILHQIEALANAGCTDIVLAVNYKPEVM 60

Query: 61  IETVKSV--DWDANIEFIYQGEPKGLAHAILVARDYLGNDDF-VMYLGDNILREGIVRHK 117
           +  +K    ++  +I F  + EP G A  + +A   L  D+  +  L  +++ E  +R  
Sbjct: 61  VGALKQYEKEYGVSITFSVEEEPLGTAGPLKLAEKILKKDNTPIFVLNSDVICEYPLRDL 120

Query: 118 EHFEKS-DYDASILLCEVPNPQQFGVAELSED-GKTIKRLIEKPKHPPSNLALVGIYFFR 175
             F  +   +A+I+  +V  P ++GV     D    I+R +EKP     N    GIY   
Sbjct: 121 LEFHTAHGGEATIVATKVDEPSKYGVIVHDRDVPNLIERFVEKPVEFVGNRINAGIYVLN 180

Query: 176 PIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVL 235
           P + + +     S  +E         L++   K+    + G+W D G+P+D L    L L
Sbjct: 181 PSVIDLIEMRPTSIEHE-----TFPILVEQ-KKLYSFDLPGYWMDVGQPKDFLSGMCLYL 234

Query: 236 DEIERE---IKVETRAKII--GRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTS 290
             + ++   +   T  + +  G V I+  AKI +   I    VIG N +I +      ++
Sbjct: 235 SALTKKNSNLLTSTSEEYVNGGNVLIDPSAKIGKGCKIGPNVVIGPNCIIGDGVRIQRST 294

Query: 291 VGNNVVIEDTEVEDSIIMDGSVIIGAGRIIE--SIIGKEVRI 330
           +  N  I+D     S I+  +  +G    +E  +++G++V +
Sbjct: 295 ILKNSQIKDHAWVKSTIVGWNSTVGKWARLEGVTVLGEDVTV 336


>gi|11497858 glucose-1-phosphate thymidylyltransferase (graD-1) [Archaeoglobus
           fulgidus] >gi|7448175|pir||B69280 glucose-1-phosphate
           thymidylyltransferase (graD-1) homolog - Archaeoglobus
           fulgidus >gi|2650399|gb|AAB90991.1| (AE001089)
           glucose-1-phosphate thymidylyltransferase (graD-1)
           [Archaeoglobus fulgidus]
           Length = 332
           
 Score =  110 bits (273), Expect = 2e-23
 Identities = 99/349 (28%), Positives = 167/349 (47%), Gaps = 35/349 (10%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNK--- 57
           MK +I++GGY TRL P+T S+ K L+PV  K ++ +  E V++       I++  NK   
Sbjct: 1   MKVIIMAGGYATRLWPITKSKAKPLLPVGTKRIVDHVYEKVLK---FNSPILLSTNKRFE 57

Query: 58  EQVIETVKSVDWDANIEFIYQGEPK-GLAHAILVARDYLGNDDFVMYLGDNILREGIVRH 116
           E   +  +  D +  +E   + E K G   A+    + + +DDF++  GDNI    +   
Sbjct: 58  EDFRKWAEGKDVEVVVEDTMREEEKLGAVKALAQVVEGI-DDDFLVVAGDNIFSFELNPI 116

Query: 117 KEHFEKSDYDASIL--LCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFF 174
            E F K     + L  + +    +++GVAEL  +G+ ++R  EKP+ P S L  + IY F
Sbjct: 117 VELFRKKKSPVTALYDVGDYELAKRYGVAEL--EGEIVRRFYEKPEKPASTLVGIAIYTF 174

Query: 175 -RPIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRL 233
            R I    V ++  + R++  + D + +L       G     G W D G P+  +EA + 
Sbjct: 175 PREIADLLVEYVGGNERSD-NLGDFLSYLCQKMDVYGCIFDNGNWYDVGNPDSYIEAFKF 233

Query: 234 VLDEIEREIKVETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIR-NAYIGPYTSVG 292
             D    E            V++ + AKI E      P VI R+ VI+  + +GPY  +G
Sbjct: 234 YTDSFVHE-----------SVEVAKAAKIIE------PVVIERDVVIKGRSIVGPYAYIG 276

Query: 293 NNVVIEDTEVEDSIIMDGSVIIGAGRIIESIIGK--EVRIVRGDGHPLG 339
               I+ ++V +S++   +V+    R+  SII    E+R +   G  +G
Sbjct: 277 EGCEIDSSDVSESVVFSKTVLKRV-RLWRSIIDDDCEIRNIELSGSIIG 324


>pir||A70978 probable rmlA2 protein - Mycobacterium tuberculosis (strain H37RV)
           >gi|1877319|emb|CAB07091.1| (Z92771) rmlA2
           [Mycobacterium tuberculosis]
           Length = 359
           
 Score =  109 bits (269), Expect = 6e-23
 Identities = 89/345 (25%), Positives = 154/345 (43%), Gaps = 25/345 (7%)

Query: 3   ALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQVIE 62
           A++L GG GTRLRPLT S  K ++P A  P L + +  +  AGI    +I+G + +  + 
Sbjct: 8   AVVLVGGKGTRLRPLTLSAPKPMLPTAGLPFLTHLLSRIAAAGIEH--VILGTSYKPAVF 65

Query: 63  TVKSVDWDA---NIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKEH 119
             +  D  A    IE++ +  P G    I      L ND  +++ GD +    + +  + 
Sbjct: 66  EAEFGDGSALGLQIEYVTEEHPLGTGGGIANVAGKLRNDTAMVFNGDVLSGADLAQLLDF 125

Query: 120 FEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPIIH 179
              +  D ++ L  V +P+ FG     E+ + +   +EK + PP++    G Y F   + 
Sbjct: 126 HRSNRADVTLQLVRVGDPRAFGCVPTDEEDRVV-AFLEKTEDPPTDQINAGCYVFERNVI 184

Query: 180 EAVRHIKPSWRN---ELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLD 236
           + +    P  R    E E+  A+  L D   K+       +W+D G PED +  +  ++ 
Sbjct: 185 DRI----PQGREVSVEREVFPAL--LADGDCKIYGYVDASYWRDMGTPEDFVRGSADLVR 238

Query: 237 EIEREIKVETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSVGNNVV 296
            I     +       G   + +GA +    ++ G  V+G     R A IGP T +   V+
Sbjct: 239 GIAPSPALRGHR---GEQLVHDGAAVSPGALLIGGTVVG-----RGAEIGPGTRLDGAVI 290

Query: 297 IEDTEVEDSIIMDGSVIIGAGRIIESIIGKEVRIVRGDGHPLGRR 341
            +   VE   +++ S+I    RI    + ++   V GDG  +G R
Sbjct: 291 FDGVRVEAGCVIERSIIGFGARIGPRALIRDG--VIGDGADIGAR 333


>pir||S76785 hypothetical protein - Synechocystis sp. (strain PCC 6803)
           >gi|1653786|dbj|BAA18697.1| (D90916) mannose-1-phosphate
           guanyltransferase [Synechocystis sp.]
           Length = 843
           
 Score =  106 bits (262), Expect = 4e-22
 Identities = 97/377 (25%), Positives = 177/377 (46%), Gaps = 52/377 (13%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           M+A++++GG GTRLRPLT    K ++P+ N+P+             H I ++   N  +V
Sbjct: 1   MRAVLMAGGAGTRLRPLTCDLPKPMVPIVNQPI-----------AAHIIHLLRRHNITEV 49

Query: 61  IETVKSVDWDANIEFIYQGEPKGLAHAILVARDY-------------LGNDDFVMYLGDN 107
           + T+  +  DA  ++   G   G+     V  ++             L +D F++  GD+
Sbjct: 50  VATLHYLP-DAMRDYFLDGSEFGVQMTYAVEDEHPLGTAGCVKNIEELLDDTFLVISGDS 108

Query: 108 I----LREGIVRHKEHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPP 163
           I    L + I  HK+   K    A+++L +VPNP +FGV  ++++ + ++R +EKP    
Sbjct: 109 ITDFNLTQAIAFHKQKQAK----ATLILTKVPNPLEFGVV-ITDENQRVQRFLEKPSTSE 163

Query: 164 --SNLALVGIYFFRPIIHEAVRHIKPSWRNELEIT-DAIQWLIDNGYKVGWTKVTGWWKD 220
             S+    G Y   P   E + ++ P  + E++ + D    L++N   +      G+W D
Sbjct: 164 VFSDTVNTGTYILEP---EVLAYLPP--KEEMDFSKDLFPLLLENDEPMYGFVADGYWCD 218

Query: 221 TGKPEDLLEANRLVLDEIEREIKVET-RAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAV 279
            G  +   EA     D +E+++ +E         + I E   ID   I+  P  IG N  
Sbjct: 219 VGNLDAYREAQ---YDALEKKVTLELGNLPRHSDIWIGENTTIDPTAILTPPLAIGDNCN 275

Query: 280 I-RNAYIGPYTSVGNNVVI-EDTEVEDSIIMDGSVIIGAGRIIESIIGKEVRIVRG---- 333
           I     +   T +G+NV I    E++ +I+ +G +I     +   ++G+  RI R     
Sbjct: 276 IGSGTKLEAGTIIGDNVTIGAGAELKRAIVWNGVLIGDEAYLAACVVGRGCRIERRVQVL 335

Query: 334 DGHPLGRRLIVGDKSQL 350
           +G  +G   I+G+++Q+
Sbjct: 336 EGAVIGPLSIIGEEAQI 352


>pir||C70354 UDP-N-acetylglucosamine pyrophosphorylase - Aquifex aeolicus
           >gi|2983227|gb|AAC06824.1| (AE000698)
           UDP-N-acetylglucosamine pyrophosphorylase [Aquifex
           aeolicus]
           Length = 464
           
 Score =  105 bits (260), Expect = 7e-22
 Identities = 104/366 (28%), Positives = 175/366 (47%), Gaps = 51/366 (13%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           M+A+IL+ G GTR +     + K L  +  KP+L+Y I +V    I +I ++VG   ++V
Sbjct: 1   MRAVILAAGLGTRFKS---EKPKVLHEILGKPMLWYVITNVRNGRIDDIAVVVGHKAQEV 57

Query: 61  IETVKSVDWDANIEFIYQGEPKG-LAHAILVARDYLGN-DDFVMYL-GDNILREG-IVRH 116
           +E  K+     N++F  Q  PKG  A A+L A+D+  + + +V+ + GD+ L  G  +R+
Sbjct: 58  MEAFKN----ENLKFFIQENPKGGTADAVLAAKDFFSSYEGYVLIINGDSPLVSGETIRN 113

Query: 117 KEHF-------EKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALV 169
            + F       E       +L   +P+P  +G     E    I R++E+    P   A+ 
Sbjct: 114 MQQFIHMVRTYEGIKLGGVVLTTHLPDPTGYGRIIKEEGTDRIIRIVEEKDATPEEKAIT 173

Query: 170 GI-----YFFRPIIHEAVRHIKPS-WRNELEITDAIQWLIDNGYKVGWTKV--------- 214
            I      F+ P + EA+  IKPS    EL +TD I+++++ GY+V              
Sbjct: 174 EINAGTYIFYAPYLLEALYRIKPSPVTGELYLTDVIEYMVNKGYEVRSFMAKEPTEALGV 233

Query: 215 -TGWWKDTGKPEDLLE-------ANRLVLDEIEREIKVETRAKIIGRVKIEEGAKIDENT 266
            T W  D    E++++       A R V       + +E    I   V+I     +   T
Sbjct: 234 NTRW--DLALVENVIKLKIARYWAERGVTVHYPETVWIEPDVSIEPDVEIFPDVMLKGKT 291

Query: 267 IIKGPAVIGRNAVIRNAYIGPYTSVGNNVVI-EDTEVEDSIIMDGSVIIGAGRI-IESII 324
            IK  +VIG+ +VI+++       V  NV++ E + +E+S I   +V+    RI  ES+I
Sbjct: 292 KIKKGSVIGKGSVIKDSL------VEENVIVREYSVIENSEIKKRAVVGPFARIRNESVI 345

Query: 325 GKEVRI 330
           G+E  I
Sbjct: 346 GEEAEI 351


>gb|AAK40709.1| Sugar phosphate nucleotydyl transferase [Sulfolobus solfataricus]
           Length = 363
           
 Score =  102 bits (251), Expect = 8e-21
 Identities = 107/344 (31%), Positives = 163/344 (47%), Gaps = 42/344 (12%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MKA++L+GG G  L P T   QK+ I V  K ++ Y IE + +AG+ E  IIV     Q+
Sbjct: 4   MKAIVLAGGKGEGLLPYTEKVQKEAITVLGKAIINYTIEGLKKAGVKEFEIIVNEKGNQI 63

Query: 61  IETVKSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKEHF 120
            E V+ +  D + E I Q + +G+  A+L   + + +D FV+  GD I           F
Sbjct: 64  EEEVEKL--DVSFETIVQ-KKQGIDGAVLEGIESIDDDVFVLAFGDIIA-------PAEF 113

Query: 121 EKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPK--HPPSNLALVGIYFF-RPI 177
            KS  D  I+           ++E +E    +K +  K K     S LAL G Y   +P 
Sbjct: 114 YKSLMDTYIMTGSQAVIPLIPISEGTETYGLVKIVDNKLKVVKESSTLALGGAYILPKP- 172

Query: 178 IHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLDE 237
                   K ++ + L+  D +       Y + W++    W D G PEDLL A   +L  
Sbjct: 173 --------KDNFTSLLDYIDLLSSQARLNYFI-WSES---WVDIGYPEDLLFALETLLRR 220

Query: 238 IEREI--KVE-TRAKIIGR-VKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSVGN 293
            E  I  K E ++  IIG+ V IE+ A I++  IIKGPA IG     +NAY+G ++ V +
Sbjct: 221 KESVISDKAEISKNAIIGKGVIIEDYAIIEDYAIIKGPAYIG-----KNAYVGSFSLVRD 275

Query: 294 NVVIED-------TEVEDSIIMDGSVIIGAGRIIESIIGKEVRI 330
              IE+        E+  S+I   + +     +  SI+GK  +I
Sbjct: 276 YSSIEEGAKIGAYCEIAHSLIEPFAEVGSKSYLTYSIVGKGAKI 319


>pir||A72403 glucose-1-phosphate adenylyltransferase - Thermotoga maritima
           (strain MSB8) >gi|4980737|gb|AAD35330.1|AE001707_17
           (AE001707) glucose-1-phosphate adenylyltransferase
           [Thermotoga maritima]
           Length = 370
           
 Score = 99.8 bits (245), Expect = 4e-20
 Identities = 92/358 (25%), Positives = 175/358 (48%), Gaps = 47/358 (13%)

Query: 4   LILSGGYGTRLRPLTYSQQKQLIPVANK-PVLFYAIEDVIEAGIHEIGIIVGPNKEQVIE 62
           LIL+GG   RL PLT  +    +PV  K   + + + +++ +GI ++GI+   N   +++
Sbjct: 6   LILAGGKSDRLWPLTKVRASAAVPVFGKYRAIDFTLSNMVNSGIRKVGILTQYNPRSLMD 65

Query: 63  TVKS-VDWDA----------------NIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLG 105
            + S  +WD                 N E  Y+G    +   + + R   G +D V+   
Sbjct: 66  HLGSGKEWDLDRKSGGLFILQPYVGPNREVWYRGTADAIFQNMTILRR--GEEDHVLIGS 123

Query: 106 DNILREGIVRHKEHFE-KSDYDASILLCEVP---NPQQFGVAELSEDGKTIKRLIEKPKH 161
            + + + I R   ++  K   D ++++ E+    N  ++G+ +L +D + ++ + EKP H
Sbjct: 124 GDHIYKMIYRDLFNYHLKKGADITLVVKELDETYNLSEYGIVQLDDDMRVVE-IEEKPAH 182

Query: 162 PPSNLALVGIYFF-RPIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKD 220
           P  N+A +G+YF  + ++ E +    P  + +L +   I  L  +  KV   +  G+W++
Sbjct: 183 PKGNIAFLGVYFMNKELLKELLYATVPQGKYDLLLDIVIPNL--DRLKVYAYRFDGYWRN 240

Query: 221 TGKPEDLLEANRLVLDEIEREI---------KVETRAKIIGRVKIEEGAKIDENTIIKGP 271
             K   + E  R+ +D +++E+         KV T+ K +   K    A ++ + I  G 
Sbjct: 241 VKK--GIKEYYRINMDILKKEVRDELFYRNGKVYTKLKDLPPPKFTTTAVVENSLIADGS 298

Query: 272 AVIG--RNAVI-RNAYIGPYTSVGNNVVIEDTEVED-----SIIMDGSVIIGAGRIIE 321
            V G  RN+VI RN  I     V N++++E+T VE+     ++I+D + I+  GR+IE
Sbjct: 299 IVSGTVRNSVIFRNVRIKVGAVVENSIIMENTVVEEGAVLRNVILDKNCIVREGRVIE 356


>gb|AAD19415.1| (AF102543) UTP-glucose-1-phosphate uridyltransferase; UDPGP
           [Zymomonas mobilis]
           Length = 292
           
 Score = 96.7 bits (237), Expect = 4e-19
 Identities = 76/279 (27%), Positives = 132/279 (47%), Gaps = 37/279 (13%)

Query: 2   KALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQVI 61
           KA+    G GTR  P T +  K+++PV ++P++ YA+++   AGI E+  + G  K Q I
Sbjct: 6   KAIFPVAGQGTRFLPATKAMPKEMLPVVDRPLIQYAVDEARAAGIEELIFVTGRGK-QAI 64

Query: 62  ETVKSVDWDANIE------------------------FIYQGEPKGLAHAILVARDYLGN 97
           E    + ++                            FI Q EP GL HA+  ARD +G+
Sbjct: 65  EDYFDIAYELEASLTAKGKTGMLDLLEGTRVAPGRACFIRQQEPLGLGHAVWCARDLIGD 124

Query: 98  DDFVMYLGDNIL----REGIVRHKEHFEKSDYDASILLCEVP--NPQQFGVAELSE-DGK 150
           + F + L D +L    R  +V+  E + +   +  + + EVP  +  ++G+ +  + DG+
Sbjct: 125 EPFAVLLPDELLWNPKRPSLVQLVETYNQKGGNV-VTVMEVPEEHTHRYGIVDPGKTDGE 183

Query: 151 T--IKRLIEKPKHPPSNLALVGIYFFRPIIHEAVRHIKPSWRNELEITDAIQWLIDNGYK 208
              +K L+EKP+  PS LA+ G Y  +P I   +         E+++TD++  LI     
Sbjct: 184 VTEVKGLVEKPEKAPSRLAMTGRYILQPDIMPLLAQDNRGVGGEIQLTDSMAQLIGK-QP 242

Query: 209 VGWTKVTGWWKDTGKPEDLLEAN-RLVLDEIEREIKVET 246
               +  G   D G     ++AN  L L+  +  +++ET
Sbjct: 243 FHACRFGGIRHDCGDKAGFIQANVALALERPDIGLRLET 281


>pir||F72591 probable sugar phosphate transferase APE1202 - Aeropyrum pernix
           (strain K1) >gi|5104874|dbj|BAA80188.1| (AP000061) 360aa
           long hypothetical sugar phosphate transferase [Aeropyrum
           pernix]
           Length = 360
           
 Score = 92.1 bits (225), Expect = 9e-18
 Identities = 77/289 (26%), Positives = 141/289 (48%), Gaps = 24/289 (8%)

Query: 59  QVIETVKSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDD-FVMYLGDNILRE---GIV 114
           +V+E V++  +   + F+ QG   G  HA+    + LG +  F    GD  L     G++
Sbjct: 7   EVVEAVRACGF-GGVRFVEQGGALGTGHAVRRVLEELGGEGVFTFVYGDVYLDSRFYGLL 65

Query: 115 RHKEHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFF 174
              E         S+L   V + + +G+ ++ +    ++ ++EKP+ P      +G +  
Sbjct: 66  ASAEA-------PSVLAGWVEDARWYGLLDVGDG--LVRGVVEKPREPRGGWVFLGGFKV 116

Query: 175 RPIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGW-WKDTGKPEDLLEANRL 233
                  +R ++PS R E+E+TDA++ L   G         GW W D G+P D+L ANR+
Sbjct: 117 DGSFLGLLRGLEPSPRGEVEVTDALEALAREGVLRALVGGEGWGWVDVGRPWDVLRANRM 176

Query: 234 VLDEIER----EIKVETRAKIIG---RVKIEEGAKIDENTIIKGPAVIGRNA-VIRNAYI 285
              + +     E +V + A + G   R+ I  GA+I  +++++GPA IG  A V   A++
Sbjct: 177 AFHDPQFSGGVEGEVHSSAVLEGDVERIYIARGARIGAHSVVEGPAYIGPGARVGPGAHV 236

Query: 286 GPYTSVGNNVVIE-DTEVEDSIIMDGSVIIGAGRIIESIIGKEVRIVRG 333
             YT +     +   +EV+ S+IM+G+       + +S++G+ V +  G
Sbjct: 237 RGYTVLLEGAYVGFASEVKASVIMEGARAPHLNYVGDSVVGEHVNLGAG 285


>gb|AAK41261.1| Sugar phosphate nucleotydyl transferase [Sulfolobus solfataricus]
           Length = 422
           
 Score = 91.7 bits (224), Expect = 1e-17
 Identities = 110/397 (27%), Positives = 173/397 (42%), Gaps = 75/397 (18%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHE--IGIIVGPNKE 58
           +K +I  GG  TRLRPLT    K  + + N+P++ Y I ++ + GI E   G+    N  
Sbjct: 10  VKVIIPIGGEATRLRPLTIETSKAAVRLLNRPLIEYTILELAKQGIKEFIFGVKGYVNYR 69

Query: 59  QVIETVK-SVDWDA------NIEFIYQG--EPKGLAHAILVARDYLG-NDDFVMYLGDNI 108
            + +  K  + + A       + F YQ   +  G A ++ +  +Y   N+  V+  GDNI
Sbjct: 70  SLFDLFKEGIGFSARYKIKPRVHFKYQPRVDSIGNADSVRINIEYYDINEPIVVVQGDNI 129

Query: 109 LREGIVRHKE-HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKH---PPS 164
            +  I +  E H  KS     +L     +  +FGVA+ + D   I++ +EKPK     PS
Sbjct: 130 FKLDITKALEFHESKSSLMTIVLKKYEGDLSEFGVADTTGD-LAIRKFVEKPKRREDAPS 188

Query: 165 NLALVGIYFFRPIIHEAVR--HIKPSWR-NELEI-TDAIQWLIDNGYKVGWTKVTGWWKD 220
           +L   GIY   P I +  +   +K  ++  +++   D I +LI+ GY V    +   W D
Sbjct: 189 DLINTGIYILSPEIRKIFKSNDVKEMYKMGKMDFGKDIIPYLINKGYPVYGYPMKEIWFD 248

Query: 221 TGKPEDLLEA--------------------NRLVL------------DEIERE-----IK 243
            G PE  L+A                    NR +              EI+R+     IK
Sbjct: 249 IGTPERYLDAMVTLLHTLSDSEIGGIRIDPNRRIFVQGTSPDSRKRRREIQRKFKKGLIK 308

Query: 244 VETRAKI-----IGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYIGPYTSVGNNVVIE 298
           +E  A I     IG     E + ID  T+I     I R+A++   YIG    + N+++  
Sbjct: 309 IEGDALIGRHCQIGDDTYIEESNIDNFTMIGKGVKIVRSAIMDRGYIGDNVHIENSIIAR 368

Query: 299 DTEVE----------DSIIMDGSVIIGAG-RIIESII 324
             E+           +S+I D  VI+G G  II S I
Sbjct: 369 HVEIRSNNEKPVRIINSVIAD-DVIVGEGTEIINSRI 404


>sp|P39122|GLGC_BACSU GLUCOSE-1-PHOSPHATE ADENYLYLTRANSFERASE (ADP-GLUCOSE SYNTHASE)
           (ADP-GLUCOSE PYROPHOSPHORYLASE) >gi|1071860|pir||S40049
           glucose-1-phosphate adenylyltransferase (EC 2.7.7.27)
           glgC - Bacillus subtilis >gi|397489|emb|CAA81041.1|
           (Z25795) ADP-glucose pyrophosphorylase [Bacillus
           subtilis] >gi|2293137|gb|AAC00215.1| (AF008220)
           ADP-glucose pyrophosphorylase [Bacillus subtilis]
           >gi|2635581|emb|CAB15075.1| (Z99119) glucose-1-phosphate
           adenylyltransferase [Bacillus subtilis]
           Length = 380
           
 Score = 91.3 bits (223), Expect = 2e-17
 Identities = 93/370 (25%), Positives = 169/370 (45%), Gaps = 56/370 (15%)

Query: 3   ALILSGGYGTRLRPLTYSQQKQLIPVANK-PVLFYAIEDVIEAGIHEIGIIVGPNKEQVI 61
           A++L+GG G+RL  LT +  K  +    K  ++ + + +   +GI  +GI+    + Q +
Sbjct: 7   AMLLAGGKGSRLSGLTKNMAKPAVSFGGKYRIIDFTLSNCSNSGIDTVGIL---TQYQPL 63

Query: 62  ETVKSVD----WDANIEFIYQGEP---------------KGLAHAILVARDYLGNDD--F 100
           E    +     WD +    Y G                 KG A +I    +YL   D  +
Sbjct: 64  ELNSYIGIGSAWDLD---RYNGGVTVLPPYAESSEVKWYKGTASSIYENLNYLNQYDPEY 120

Query: 101 VMYL-GDNILREGIVRHKEHFEKSDYDASILLCEV--PNPQQFGVAELSEDGKTIKRLIE 157
           V+ L GD+I +    +  ++  +   D +I + EV      +FG+ + + DG TI    E
Sbjct: 121 VLILSGDHIYKMDYGKMLDYHIEKKADVTISVIEVGWEEASRFGIMKANPDG-TITHFDE 179

Query: 158 KPKHPPSNLALVGIYFFR-PIIHEAVRHIKPSWRNELEI-TDAIQWLIDNGYKVGWTKVT 215
           KPK P SNLA +GIY F  P++ + +     +  +  +   D I  L++   K+      
Sbjct: 180 KPKFPKSNLASMGIYIFNWPLLKQYLEMDDQNPYSSHDFGKDIIPLLLEEKKKLSAYPFK 239

Query: 216 GWWKDTGKPEDLLEANRLVLDEIEREIKVETRAKIIGRVK-------IEEGAKIDENTII 268
           G+WKD G  + L EAN  +L E + E+K+  R   I  V        I   A++ ++ + 
Sbjct: 240 GYWKDVGTVQSLWEANMDLLKE-DSELKLFERKWKIYSVNPNQPPQFISSDAQVQDSLVN 298

Query: 269 KGPAV--------------IGRNAVIRNAYIGPYTSVGNNVVIEDTEVEDSIIMDGSVII 314
           +G  V              +G++  + ++ I P  ++G +VVIE+  V + +++    +I
Sbjct: 299 EGCVVYGNVSHSVLFQGVTVGKHTTVTSSVIMPDVTIGEHVVIENAIVPNGMVLPDGAVI 358

Query: 315 GAGRIIESII 324
            + + IE ++
Sbjct: 359 RSEKDIEEVL 368


>pir||D72592 probable glucose-1-phosphate thymidylyltransferase APE1208 -
           Aeropyrum pernix (strain K1) >gi|5104880|dbj|BAA80194.1|
           (AP000061) 360aa long hypothetical glucose-1-phosphate
           thymidylyltransferase [Aeropyrum pernix]
           Length = 360
           
 Score = 88.5 bits (216), Expect = 1e-16
 Identities = 90/334 (26%), Positives = 150/334 (43%), Gaps = 25/334 (7%)

Query: 4   LILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDV--IEAGIHEIGIIVGPNKEQVI 61
           ++L+GG G RL PLT  + K  +P+A KP+  YA+E V  + + +    ++  P      
Sbjct: 1   MVLAGGVGKRLLPLTRERPKPYLPLAGKPLYMYAVEQVAMVRSLLDRAVMVTPPGHPTPP 60

Query: 62  ETVKSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHK-EHF 120
            ++ S  W   +E   +G   GLA A+   R   G +  V ++G       +VRH  + +
Sbjct: 61  GSLPS--WLDTVEQQGEGVEAGLATAL--KRLGGGEEVVVSFVGYLARPNTLVRHVLDFY 116

Query: 121 EKSDYDASILLCEVPN-PQQFGVAELSEDGKTIKRLIEKPKHPPSNLALV--GIYFFRPI 177
             + Y   + L  V    + FG  +       +       +   +    V  G+    P 
Sbjct: 117 SVTRYKLVLALAPVTRGSESFGFVDADPSTGRVLGFSGSREEWMAGRGRVFAGVLAGDP- 175

Query: 178 IHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVLDE 237
             EA+  +           + I  L   G  VG     G W + G P DLLEA RLV++ 
Sbjct: 176 --EALEVLAGEG-----FVEGINTLARRGL-VGSVVWPGEWLEVGYPCDLLEAPRLVVEA 227

Query: 238 ----IEREIKVETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVI-RNAYIGPYTSVG 292
               I  + +V   + I G V IEE A++ E  +++GPA +GR AV+ RN+ +GP   + 
Sbjct: 228 WAAVISAKARVARSSVIQGGVVIEEDAEVGEGAVVEGPAYLGRGAVVGRNSVVGPGVVLE 287

Query: 293 NNVVIED-TEVEDSIIMDGSVIIGAGRIIESIIG 325
              V+ D   +E S++++ +   G  R+   +IG
Sbjct: 288 EGAVVGDLVSIERSVMLERAEASGPSRLEGVVIG 321


>gb|AAF81069.1|AF223364_4 (AF223364) mannose-1-phosphate-guanyltransferase-like protein
           [Myxococcus xanthus]
           Length = 342
           
 Score = 85.0 bits (207), Expect = 1e-15
 Identities = 96/364 (26%), Positives = 157/364 (42%), Gaps = 60/364 (16%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MKA++L  G GTRLRPLT    K  +P   +P+L Y +  +  AG+  +GI    N   +
Sbjct: 1   MKAMVLCAGLGTRLRPLTERWPKPAMPFLGQPLLRYHLAVLKAAGVTAVGI----NTHHL 56

Query: 61  IETVKSVDWDANIEFIYQGEP---------KGLAHAILVARDYLGNDDFVMYLGDNI--- 108
            +T+++V   A  E    G P         +G    I   RD+L + DF+++ GD +   
Sbjct: 57  PDTMEAV---ARAECARAGLPLHVVNEPVIQGTGGGIRGLRDFLSDGDFIVFNGDILYPV 113

Query: 109 -LREGIVRHKEHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLA 167
            LR  +  H    + S   A+++L  +P  + +   EL  +G+ ++R+     H P    
Sbjct: 114 DLRPVVALH----QASGALATMVLQPMPAGETYAAVELDAEGR-VRRI---AGHGPGGEG 165

Query: 168 L-----VGIYFFRPIIHEAVRHIKPSWRNELEITDAIQ-WLIDNGYKVGWTKVTGWWKDT 221
           L      G++   P + + +     S R E +I   +    ++ G  V   +V G+W D 
Sbjct: 166 LSPWHFTGVHVMSPRVFDFM-----SPRGEEDINRGVYVRAMEAGQMVRGVRVDGYWSDL 220

Query: 222 GKPEDLLEANRLVLDEIEREIKVETRAKIIGRVKIEEG------AKIDENTIIKGPAVIG 275
           G P   L   + VL    R   +   + + G V+   G      A++D     +GP  +G
Sbjct: 221 GTPSRYLATVQDVLAGHVRLEWLGADSPLAGTVRGASGTWAHAEARLDGTA--EGPVYLG 278

Query: 276 R-NAVIRNAYIGPYTS------------VGNNVVIEDTEVEDSIIMDGSVIIGAGRIIES 322
           R +AV   A +GP  S            +    V EDTEV     +   +  GA RI   
Sbjct: 279 RGSAVAAGAAVGPGVSLEPGAKVAAGARLSRATVFEDTEVSSGESLSEVLAWGAHRIAAP 338

Query: 323 IIGK 326
           + G+
Sbjct: 339 LKGR 342


>emb|CAB88923.1| (AL353862) putative nucleotide phosphorylase [Streptomyces
           coelicolor A3(2)]
           Length = 360
           
 Score = 83.1 bits (202), Expect = 5e-15
 Identities = 89/342 (26%), Positives = 154/342 (45%), Gaps = 43/342 (12%)

Query: 2   KALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQVI 61
           +A++L GG GTRLRPLT +  K ++  A  P L + +     AG+  I ++      +V 
Sbjct: 3   EAILLVGGKGTRLRPLTVNTPKPMVRAAGVPFLTHQLARAKAAGVEHI-VLATSYLAEVF 61

Query: 62  ETV--KSVDWDANIEFIYQGEPKGLAHAI--LVARDYLGNDDFVM-YLGDNILREGIVRH 116
           E           ++E++ + EP G   AI  + +R + G D+ V+ + GD +    I   
Sbjct: 62  EPYFGDGSTLGLHLEYVTEEEPLGTGGAIRNVASRLHSGPDEPVLIFNGDILTGLDIGAL 121

Query: 117 KEHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPP---SNLALVGIYF 173
               E +  D S+ L +V +P+ +G+    + G+ +   +EKP+ P    ++    G Y 
Sbjct: 122 VRTHETTGADVSLHLTQVTDPRAYGLVPTDDTGRVL-AFLEKPQTPEEIVTDQINAGAYV 180

Query: 174 FRPIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLE---- 229
           FR  + + +    P+ R      +    L+  G  +     + +W D G P   +     
Sbjct: 181 FRRSVIDTI----PAGRPVSVERETFPELLATGAHLQGMVDSTYWLDLGTPAAFVRGSAD 236

Query: 230 ---------------ANRLVLD--EIEREIKVETRAKIIGR-VKIEEGAKIDENTIIKGP 271
                           +RLVL   ++  + K+ T   ++G    + EGA++  +TI+ G 
Sbjct: 237 LVLGRAPSPAVPGRCGDRLVLPTAQVAPDAKL-TGGTVVGEGAFVAEGARVFGSTILPG- 294

Query: 272 AVIGRNAVIRNAYIGPYTSVGNNVVIEDTEVEDSIIMDGSVI 313
           AVI   AVI ++ IG    VG   V+ DT     +I DG+VI
Sbjct: 295 AVIEPGAVITDSLIGTRARVGTRSVLADT-----VIGDGAVI 331


>pir||B72403 glucose-1-phosphate adenylyltransferase - Thermotoga maritima
           (strain MSB8) >gi|4980738|gb|AAD35331.1|AE001707_18
           (AE001707) glucose-1-phosphate adenylyltransferase
           [Thermotoga maritima]
           Length = 423
           
 Score = 82.3 bits (200), Expect = 8e-15
 Identities = 89/371 (23%), Positives = 163/371 (42%), Gaps = 49/371 (13%)

Query: 3   ALILSGGYGTRLRPLTYSQQKQLIPVANKPVLF-YAIEDVIEAGIHEIGIIVGPNKEQVI 61
           A+IL+GG GTRL  LT    K  +P   K  L  + + + + +GI+ +G++       + 
Sbjct: 6   AMILAGGQGTRLGVLTERIAKPAVPFGGKYRLIDFTLSNCVNSGIYRVGVLTQYRPHVLS 65

Query: 62  ETVK-SVDWDAN-----IEFI--YQGEP-----KGLAHAILVARDYLGNDDFVMYL---G 105
           + +     WD +     +E +  Y G       KG A+A+    ++L  +D  + L   G
Sbjct: 66  KHIGIGRPWDLDRKDGGVEILPPYVGRHESDWYKGTANAVYQNLEFLEENDAELVLILSG 125

Query: 106 DNILREGIVRHKEHFEKSDYDASILLCEVP--NPQQFGVAELSEDGKTIKRLIEKPKHPP 163
           D++         ++    + D +I   EVP     +FG+     DG+ +    EKP  P 
Sbjct: 126 DHVYAMNYNDLIDYHLLKEADGTIACMEVPIEEASRFGIMITDVDGRIVD-FEEKPAKPR 184

Query: 164 SNLALVGIYFFRPIIHEAVRHIKPSWRNELEIT-----DAIQWLI-DNGYKVGWTKVTGW 217
           SNLA +GIY F    +E ++ +     N+   +     D I  ++ +N   +   +  G+
Sbjct: 185 SNLASLGIYVFN---YEFLKKVLIEDENDPNSSHDFGKDVIPRILRENLGSLYAFRFDGY 241

Query: 218 WKDTGKPEDLLEAN-RLVL-----DEIEREIKVETRAKIIGRVKIEEGAKIDENTIIKGP 271
           W+D G      EAN  LVL     +  +   +  T  + +    +  G+K+  + + +G 
Sbjct: 242 WRDVGTLRSYWEANLELVLPVPPFNLYDPNWRFFTHTEEMPPAYVAPGSKVSTSLVSEGA 301

Query: 272 AV--------------IGRNAVIRNAYIGPYTSVGNNVVIEDTEVEDSIIMDGSVIIGAG 317
            V              IGR  V++N+ I   T +G N  +E+  + +++ +  +V +G G
Sbjct: 302 EVYGNVFNSVIFQGVKIGRGTVVKNSVIMTRTEIGENCYLENVIIAENVKIGSNVRMGVG 361

Query: 318 RIIESIIGKEV 328
              ES +  +V
Sbjct: 362 EDAESKLDPKV 372


>pir||S75920 hypothetical protein - Synechocystis sp. (strain PCC 6803)
           >gi|1653465|dbj|BAA18379.1| (D90913) mannose-1-phosphate
           guanyltransferase [Synechocystis sp.]
           Length = 388
           
 Score = 81.9 bits (199), Expect = 1e-14
 Identities = 89/348 (25%), Positives = 157/348 (44%), Gaps = 35/348 (10%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           MKA+IL+ G GTR+RP+T++  K +IP+  KPV+ + +E + + G  +I + V    E++
Sbjct: 1   MKAMILAAGKGTRVRPITHTIPKPMIPILQKPVMEFLLELLRQHGFDQIMVNVSHLAEEI 60

Query: 61  IETVK---------SVDWDANI-EFIYQGEPKGLAHAILVARDY--LGNDDFVMYLGDNI 108
               +         +  ++ NI +    G+  G A  +   +++    +D FV+  GD +
Sbjct: 61  ESYFRDGQRFGVQIAYSFEGNIVDGDLVGKALGSAGGLKKIQEFNPFFDDTFVVLCGDAL 120

Query: 109 LREGIVRHKEHFEKSDYDASILLCEVPNP--QQFGVAELSEDGKTIKRLIEKP--KHPPS 164
           +   +    +   +    A+I+   VP      +GV    ++GK I    EKP  +   S
Sbjct: 121 IDLDLTTAVKLHREKGAIATIITKTVPQELVSSYGVVVTDDNGK-ILTFQEKPAVEEALS 179

Query: 165 NLALVGIYFFRPIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKP 224
                GIY F P   E + +I      +L   D    L+D+G       +   W D GK 
Sbjct: 180 TEINTGIYIFEP---EVIDYIPSGQEYDLG-GDLFPKLVDSGLPFYAVNMDFEWVDIGKV 235

Query: 225 EDLLEANRLVLDEIEREIK------VETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNA 278
            D  +A R VL    REIK      +E R  +   + +   A   +N  I+GP  IG   
Sbjct: 236 PDYWQAIRGVL---SREIKNVQIPGIEVRPGVYTGINV---AANWDNIEIEGPVYIGGMT 289

Query: 279 VIRNA--YIGPYTSVGNNVVIEDTEVEDSIIMDGSVIIGAGRIIESII 324
            I +    IGP     + ++ +   V++S+I + S +    R+++ ++
Sbjct: 290 RIEDGVKIIGPSMIGPSCLICQGAVVDNSVIFEYSRLGPGARLVDKLV 337


>dbj|BAB07043.1| (AP001518) glucose-1-phosphate thymidylyltransferase [Bacillus
           halodurans]
           Length = 463
           
 Score = 81.5 bits (198), Expect = 1e-14
 Identities = 84/354 (23%), Positives = 157/354 (43%), Gaps = 46/354 (12%)

Query: 3   ALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQVIE 62
           A+IL+ G G ++ P      K  +P+ N+  + + +  +       I I        +  
Sbjct: 4   AIILAAGKGKKMWPYNDYWPKAALPIGNQGNIVHLVNHLKSLAFERIIITTC----YLSR 59

Query: 63  TVKSVDWDAN-IEFIYQGEPKGLAHAI-LVARDYLGNDDFVMYLGDNILREGIVRHKEHF 120
            +KS+ +D   +E I     +G A  +  V  D   ++ F++Y    I RE +    E +
Sbjct: 60  RIKSLIYDVEGVEIIELSATEGTADTLEKVVYDLQDSNLFILYGDIFITRERLSSFIEAY 119

Query: 121 EKS--DYDASILLCEVPNPQQ---FGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFR 175
           EK     DA IL   + N      FG+ ++ +D + ++ +   P+       ++G +   
Sbjct: 120 EKQRETMDAVILSKPIENEHAQDWFGI-KVGKDNR-VENIFGHPRPHYVQERVMGAFALN 177

Query: 176 PIIHEAVRHIKPSW----------RNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPE 225
             + + + +  P +          + E+E+   +QWL++ GY V    VT    D  KP 
Sbjct: 178 TNVLKKMLNHNPGFMKSVPTGVMPQQEVELEQCLQWLVEVGYNVSSYPVTDGVIDMDKPW 237

Query: 226 DLLEANRLVLDEIEREIKVETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVIRNAYI 285
            L++AN L + E+            +   +I E  +ID    I+G   +G     ++  I
Sbjct: 238 HLMQANHLAVSEM---------THALNNNEIHETCEIDPTADIQGHVKLG-----KHVKI 283

Query: 286 GPYTSVGNNVVIED-TEVEDSIIMDGSVIIGAGRIIE--------SIIGKEVRI 330
           G Y ++  N VI D T++++ +I++G+V+IG+   IE        S+IG + RI
Sbjct: 284 GKYVTIKGNAVIGDYTKIDNGVIIEGNVVIGSDCRIENYCRIGPDSVIGNKNRI 337


>gb|AAG18947.1| (AE004996) glucose-1-phosphate thymidylyltransferase; GraD1
           [Halobacterium sp. NRC-1]
           Length = 342
           
 Score = 80.8 bits (196), Expect = 2e-14
 Identities = 97/342 (28%), Positives = 151/342 (43%), Gaps = 40/342 (11%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNK--- 57
           MKA++L+GGY TRL P+T  + K  +PV +  V+     D +E+      + V  N+   
Sbjct: 14  MKAVVLAGGYATRLWPITKDRPKMFLPVGDSTVIDRIFAD-LESDDRIDTVYVSTNERFA 72

Query: 58  --------EQVIETVK-SVD--WDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGD 106
                   E+  E  + SV+   D N +F   G     A A LV R+ +  DD V+  GD
Sbjct: 73  DEFRSHLAERSFEKPQLSVEDTTDENEKFGVMG-----ALAQLVDRESI-TDDLVVIAGD 126

Query: 107 NILREGIVRHKEHFEKSDYD----ASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHP 162
           N++   +    + F   D D    A+  +      Q +G+ EL   G  +    EKP  P
Sbjct: 127 NLISFDVSAFVDFFAADDADNPAIAAYDVGSYERAQSYGLVEL--HGDEVINFQEKPDDP 184

Query: 163 PSNLALVGIYFFRPIIHEAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTG 222
            S L  +  Y +   + E +     +  N  E    ++WL D      +T   G W D G
Sbjct: 185 NSTLVSIACYAYPESVVEDIDTYLAADGNPDEPGWFVEWLQDRQSVRAFT-FEGAWFDIG 243

Query: 223 KPEDLLEANRLVL--DEIEREIKVETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVI 280
            PE  L+A    L  D I  +    +   I   V +  GA++  +T+    +VI  +A +
Sbjct: 244 TPESYLDAVAWTLDGDSIVADDATVSNTTIGENVHVLPGAELTNSTV--SNSVIFPDATL 301

Query: 281 RNAYIGPYTSVGNNVVIEDTEVEDSIIMDGSVIIGAGRIIES 322
           R+        V N+++ EDT V DSI   G+ +IGA   IE+
Sbjct: 302 RDC------DVRNSIIDEDT-VLDSIDFSGA-LIGAHTTIEN 335


>dbj|BAB04806.1| (AP001510) glucose-1-phosphate adenylyltransferase [Bacillus
           halodurans]
           Length = 383
           
 Score = 76.5 bits (185), Expect = 4e-13
 Identities = 94/352 (26%), Positives = 152/352 (42%), Gaps = 49/352 (13%)

Query: 4   LILSGGYGTRLRPLTYSQQKQLIPVANK-PVLFYAIEDVIEAGIHEIGIIVGPNKEQVIE 62
           ++L+GG G RL  LT    K  +    K  ++ + + +   +GI  +G++       +  
Sbjct: 8   MLLAGGEGKRLGQLTRKLAKPAVYFGGKYRIIDFPLSNCTNSGIDTVGVLTQYEPLALNG 67

Query: 63  TVK-SVDWDAN------------IEFIYQGEPKGLAHAILVARDYLGNDD--FVMYL-GD 106
            +     WD +            IE       KG A AI   R Y+   D  +V+ L GD
Sbjct: 68  HIGIGSPWDLDRRHGGVTVLPPYIEKQGGSWYKGTADAIYQNRYYIEQYDPEYVLILSGD 127

Query: 107 NILREGIVRHKEHFEKSDYDASILLCEVP--NPQQFGVAELSEDGKTIKRLIEKPKHPPS 164
           +I +    R   H +K   DA+I + EVP     +FG+   +E+  TI +  EKP  P S
Sbjct: 128 HIYKMDYDRMISHHKKLGADATISVIEVPWEEASRFGIMNTNEE-MTITQFEEKPTTPIS 186

Query: 165 NLALVGIYFFRPIIHEA--VRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTG 222
           NLA +GIY F   + ++  ++  K +  +     D I  ++    K+      G+WKD G
Sbjct: 187 NLASMGIYIFNWSVLKSYLIQDAKQANSSHDFGKDIIPKMLAKDLKLVAYPFEGYWKDVG 246

Query: 223 KPEDLLEANRLVLDE---------------IEREIK---VETRAKIIGRVKIEEGAKID- 263
             +   EAN  +LDE               + R      + TRA +   + + EG  +  
Sbjct: 247 TIKSYWEANMDLLDEHSSLMLNDPSWRIYSVNRNQPPQYISTRAYVRCSL-VNEGCVVHG 305

Query: 264 --ENTIIKGPAVIGRNAVIRNAYIGPYTSVGNNVVIEDTEVEDSIIMDGSVI 313
             E +I+     IG N+ +  + + P   VG NVV+  T     IIM+G+ I
Sbjct: 306 NVEQSILFPGVHIGANSSVFESVLMPNVKVGENVVLRRT-----IIMEGACI 352


>pir||E72229 UDP-N-acetylglucosamine pyrophosphorylase - Thermotoga maritima
           (strain MSB8) >gi|4982202|gb|AAD36696.1|AE001806_6
           (AE001806) UDP-N-acetylglucosamine pyrophosphorylase
           [Thermotoga maritima]
           Length = 445
           
 Score = 76.5 bits (185), Expect = 4e-13
 Identities = 90/353 (25%), Positives = 159/353 (44%), Gaps = 51/353 (14%)

Query: 1   MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
           M+AL+L+ G GTR++       K L P++ +P++ + IE   +    ++G+++G   E V
Sbjct: 1   MRALVLAAGKGTRMKSKI---PKVLHPLSGRPMIEWVIETAGKVA-QKVGVVLGFEAELV 56

Query: 61  IETVKSVDWDANIEFIYQGEPKGLAHAILVARDYL--GNDDFVMYLGDNILREGIVRHKE 118
            + +   +W   ++   QGE  G AHA++ A+D++  G+D  ++Y    ++ E  ++   
Sbjct: 57  RKALP--EW---VDVFVQGEQLGTAHAVMCAKDFIEPGDDVLILYGDVPLISENTLKRMI 111

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLAL----VGIYFF 174
              +   D +IL+ ++ +P  +G   + +DG    R+IE    P    ++     G Y F
Sbjct: 112 EEHRKGADVTILVADLEDPSGYG--RVIQDGDKY-RIIEDTDLPEELKSVTTINTGFYVF 168

Query: 175 R-PIIHEAVRHIK-PSWRNELEITDAIQWL-------IDNGYK---VGWTKVTGWWKD-- 220
               +  A+  IK  + + E  +TDA+ +         D+  +   V   K   W ++  
Sbjct: 169 SGDFLLRALPEIKNENAKGEYYLTDAVNFAEKVRVVRTDDLLEITGVNTRKTLVWLEEQL 228

Query: 221 -TGKPEDLLEANRLVLDEIEREIKVETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAV 279
              K E+LLE    +LD     I           V+I     I   T I+G + +G    
Sbjct: 229 RMRKIEELLENGVTILDPATTYIHYS--------VEIGMDTVIYPMTFIEGKSRVG---- 276

Query: 280 IRNAYIGPYT-----SVGNNVVIEDTEVEDSIIMDGSVIIGAGRIIESIIGKE 327
             N  IGP T      +GNNV I  +E   S+I D   +    R+ E  I K+
Sbjct: 277 -ENCEIGPMTRIVDCEIGNNVKITRSECFKSVIEDDVSVGPFARLREGTILKK 328


>pir||S66080 UDP-N-acetylglucosamine pyrophosphorylase gcaD - Bacillus subtilis
           >gi|467439|dbj|BAA05285.1| (D26185) temperature
           sensitive cell division [Bacillus subtilis]
           >gi|2632317|emb|CAB11826.1| (Z99104)
           UDP-N-acetylglucosamine pyrophosphorylase [Bacillus
           subtilis]
           Length = 456
           
 Score = 74.5 bits (180), Expect = 2e-12
 Identities = 89/360 (24%), Positives = 160/360 (43%), Gaps = 53/360 (14%)

Query: 3   ALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQVIE 62
           A++L+ G GTR++   Y   K L PV  KP++ + +++ ++  + ++  IVG   E+V +
Sbjct: 6   AVVLAAGQGTRMKSKLY---KVLHPVCGKPMVEHVVDEALKLSLSKLVTIVGHGAEEVKK 62

Query: 63  TVKSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDD--FVMYLGDNILREGIVRH---K 117
            +         E+  Q +  G AHA+  A+ +L ++    ++  GD  L          K
Sbjct: 63  QLGD-----KSEYALQAKQLGTAHAVKQAQPFLADEKGVTIVICGDTPLLTAETMEQMLK 117

Query: 118 EHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLAL---VGIYFF 174
           EH ++ +  A+IL     +P  +G    SE+G   K +  K       L      G Y F
Sbjct: 118 EHTQR-EAKATILTAVAEDPTGYGRIIRSENGAVQKIVEHKDASEEERLVTEINTGTYCF 176

Query: 175 -RPIIHEAVRHI-KPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEAN- 231
               +  A+  +   + + E  + D I+ L + G  V   +       TG  ++ L  N 
Sbjct: 177 DNEALFRAIDQVSNDNAQGEYYLPDVIEILKNEGETVAAYQ-------TGNFQETLGVND 229

Query: 232 RLVLDEIEREIKVETRAKIIGRVKIEEGAKIDE--NTIIKGPAVIGRNAVI--------- 280
           R+ L + E+ +K     + I +  ++ G  + +  NT I   AVIG + VI         
Sbjct: 230 RVALSQAEQFMK-----ERINKRHMQNGVTLIDPMNTYISPDAVIGSDTVIYPGTVIKGE 284

Query: 281 ----RNAYIGPYTSVGNNVVIEDTEVEDSII----MDGSVIIGAGRII--ESIIGKEVRI 330
                +  IGP+T + N+ +   T ++ S++    +   V IG    I  +S+IG EV+I
Sbjct: 285 VQIGEDTIIGPHTEIMNSAIGSRTVIKQSVVNHSKVGNDVNIGPFAHIRPDSVIGNEVKI 344


>sp|P14192|GCAD_BACSU UDP-N-ACETYLGLUCOSAMINE PYROPHOSPHORYLASE
           (N-ACETYLGLUCOSAMINE-1-PHOSPHATE URIDYLTRANSFERASE) (TMS
           PROTEIN) >gi|80432|pir||S05371 tms protein - Bacillus
           subtilis >gi|40217|emb|CAA34522.1| (X16518) tms gene
           product (AA 1-456) [Bacillus subtilis]
           Length = 456
           
 Score = 71.8 bits (173), Expect = 1e-11
 Identities = 88/360 (24%), Positives = 159/360 (43%), Gaps = 53/360 (14%)

Query: 3   ALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQVIE 62
           A++L+ G GTR++   Y   K L PV  KP++ + +++ ++  + ++  IVG   E+V +
Sbjct: 6   AVVLAAGQGTRMKSKLY---KVLHPVCGKPMVEHVVDEALKLSLSKLVTIVGHGAEEVKK 62

Query: 63  TVKSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDD--FVMYLGDNILREGIVRH---K 117
            +         E+  Q +  G AHA+  A+ +L ++    ++  GD  L          K
Sbjct: 63  QLGD-----KSEYRVQAKQLGTAHAVKQAQPFLADEKGVTIVICGDTPLLTAETMEQMLK 117

Query: 118 EHFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLAL---VGIYFF 174
           EH ++ +   +IL     +P  +G    SE+G   K +  K       L      G Y F
Sbjct: 118 EHTQR-EAKRTILTAVAEDPTGYGRIIRSENGAVQKIVEHKDASEEERLVTEINTGTYCF 176

Query: 175 -RPIIHEAVRHI-KPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEAN- 231
               +  A+  +   + + E  + D I+ L + G  V   +       TG  ++ L  N 
Sbjct: 177 DNEALFRAIDQVSNDNAQGEYYLPDVIEILKNEGETVAAYQ-------TGNFQETLGVND 229

Query: 232 RLVLDEIEREIKVETRAKIIGRVKIEEGAKIDE--NTIIKGPAVIGRNAVI--------- 280
           R+ L + E+ +K     + I +  ++ G  + +  NT I   AVIG + VI         
Sbjct: 230 RVALSQAEQFMK-----ERINKRHMQNGVTLIDPMNTYISPDAVIGSDTVIYPGTVIKGE 284

Query: 281 ----RNAYIGPYTSVGNNVVIEDTEVEDSII----MDGSVIIGAGRII--ESIIGKEVRI 330
                +  IGP+T + N+ +   T ++ S++    +   V IG    I  +S+IG EV+I
Sbjct: 285 VQIGEDTIIGPHTEIMNSAIGSRTVIKQSVVNHSKVGNDVNIGPFAHIRPDSVIGNEVKI 344


>dbj|BAB03784.1| (AP001507) UDP-N-acetylglucosamine pyrophosphorylase [Bacillus
           halodurans]
           Length = 455
           
 Score = 69.5 bits (167), Expect = 6e-11
 Identities = 79/331 (23%), Positives = 141/331 (41%), Gaps = 37/331 (11%)

Query: 3   ALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQVIE 62
           A+IL+ G GTR++   Y   K L  V  KP++ + ++ V   G  EI  I+G   + V  
Sbjct: 6   AVILAAGQGTRMKSKLY---KVLHSVCGKPMVQHVVDQVSALGFDEIVTIIGHGADAVKS 62

Query: 63  TVKSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYL--GDNIL--REGIVRHKE 118
            +        + +  Q E  G  HA+L A   LG    V  +  GD  L   E I     
Sbjct: 63  QLGE-----RVSYALQEEQLGTGHAVLQAESALGGRRGVTIVLCGDTPLLTAETIDHVMS 117

Query: 119 HFEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALV----GIYFF 174
           + E+    A++L  E+ +P  +G    ++ G  ++R++E          +     G Y F
Sbjct: 118 YHEEEQAKATVLTAELADPTGYGRIVRNDKG-LVERIVEHKDATSEEKQITEVNTGTYCF 176

Query: 175 -RPIIHEAVRHI-KPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEAN- 231
               + +A++ +   + + E  + D IQ L   G KV   K       T   E+ L  N 
Sbjct: 177 DNEALFQALKEVGNNNAQGEYYLPDVIQILQTKGEKVAAYK-------TAHVEETLGVND 229

Query: 232 RLVLDEIEREIKVETRAKIIGR---------VKIEEGAKIDENTII-KGPAVIGRNAVIR 281
           R+ L + E+ +K       + +           +   A I ++T+I  G  V+G+  +  
Sbjct: 230 RVALAQAEQVMKRRINEAWMRKGVTFIDPEQTYVSPDATIGQDTVIYPGTMVLGQTTIGE 289

Query: 282 NAYIGPYTSVGNNVVIEDTEVEDSIIMDGSV 312
              +GP+T + ++ +   T V+ S++ +  V
Sbjct: 290 GCVLGPHTELKDSKIGNKTAVKQSVVHNSEV 320


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.319    0.141    0.414 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 138321757
Number of Sequences: 2977
Number of extensions: 6201581
Number of successful extensions: 15754
Number of sequences better than 1.0e-10: 235
Number of HSP's better than  0.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 205
Number of HSP's that attempted gapping in prelim test: 14955
Number of HSP's gapped (non-prelim): 275
length of query: 352
length of database: 189,106,746
effective HSP length: 54
effective length of query: 298
effective length of database: 156,788,448
effective search space: 46722957504
effective search space used: 46722957504
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 165 (68.7 bits)