BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB0787 (rfbC) DE:DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE (EC 5.1.3.13) (DTDP-4-KETO-6- DEOXYGLUCOSE 3,5-EPIMERASE) (DTDP-L-RHAMNOSE SYNTHETASE). (185 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||E75098 dTDP-4-dehydrorhamnose 3,5-epimerase (EC 5.1.3.13) P... 390 e-108 pir||A71152 probable dTDP-4-dehydrorhamnose 3,5-epimerase - Pyro... 351 3e-96 pir||S23343 hypothetical protein 7.0 - Salmonella choleraesuis >... 231 4e-60 gb|AAG09525.1|AF279621_4 (AF279621) dTDP-6-deoxy-D-glucose-3,5-e... 230 8e-60 gb|AAG09505.1|AF279616_4 (AF279616) dTDP-6-deoxy-D-glucose-3,5-e... 228 5e-59 sp|P37780|RFBC_SHIFL DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE (DTDP-... 226 1e-58 gb|AAG09540.1|AF279625_4 (AF279625) dTDP-6-deoxy-D-glucose-3,5-e... 224 7e-58 gb|AAG09501.1|AF279615_4 (AF279615) dTDP-6-deoxy-D-glucose-3,5-e... 223 1e-57 gb|AAG09529.1|AF279622_4 (AF279622) dTDP-6-deoxy-D-glucose-3,5-e... 222 3e-57 gb|AAG09516.1|AF279619_4 (AF279619) dTDP-6-deoxy-D-glucose-3,5-e... 209 2e-53 gb|AAC70776.1| (AF097519) dTDP-4-keto-6-deoxy-D-glucose 3,5-epim... 205 3e-52 sp|P26394|RFBC_SALTY DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE (DTDP-... 204 7e-52 sp|P37745|RFBC_ECOLI DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE (DTDP-... 203 1e-51 pir||B69106 dTDP-4-dehydrorhamnose 3,5-epimerase - Methanobacter... 203 2e-51 pir||E83000 dTDP-4-dehydrorhamnose 3,5-epimerase PA5164 [importe... 199 2e-50 gb|AAD40710.1|AF048749_6 (AF048749) dTDP-6-deoxy-D-glucose-3,5 e... 198 3e-50 pir||S78545 dTDP-4-dehydrorhamnose 3,5-epimerase (EC 5.1.3.13) -... 196 2e-49 pir||S76461 hypothetical protein - Synechocystis sp. (strain PCC... 195 3e-49 pir||A82013 dTDP-4-dehydrorhamnose 3,5-epimerase (EC 5.1.3.13) N... 194 6e-49 pir||A82015 dTDP-4-dehydrorhamnose 3,5-epimerase (EC 5.1.3.13) N... 194 6e-49 gb|AAG09512.1|AF279618_4 (AF279618) dTDP-6-deoxy-D-glucose-3,5-e... 192 2e-48 gb|AAC37051.1| (L09189) rfbC gene product [Neisseria meningitidis] 191 4e-48 pir||C81240 dTDP-4-keto-6-deoxy-D-glucose-3,6-epimerase NMB0081 ... 191 4e-48 pir||T31086 probable dTDP-4-dehydrorhamnose 3,5 epimerase - Serr... 189 2e-47 sp|P37763|RFBC_NEIGO DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE (DTDP-... 189 3e-47 pir||S42433 TDP-deoxyglucose epimerase - Neisseria meningitidis ... 188 4e-47 gb|AAG09533.1|AF279623_4 (AF279623) dTDP-6-deoxy-D-glucose-3,5-e... 188 4e-47 pir||T00105 dTDP-4-keto-6-deoxy-D-glucose-3,6-epimerase (EC 5.1.... 187 8e-47 dbj|BAA94405.1| (AB041266) dTDP-6-deoxy-D-xylo-4-hexulose 3,5-ep... 184 7e-46 dbj|BAA19636.1| (AB002668) dTDP-4-keto-6-deoxy-D-glucose-3,5-epi... 183 9e-46 gb|AAD05456.1| (AF064070) putative dTDP-4-keto-6-deoxy-D-glucose... 183 1e-45 gb|AAD12969.1| (AF078135) RmlC [Leptospira borgpetersenii] 183 2e-45 gb|AAC35921.1| (AF071085) dTDP-4-dehydrorhamnose 3,5-epimerase [... 180 8e-45 gb|AAB47840.1| (U61226) RfbD [Leptospira interrogans] >gi|581431... 180 1e-44 dbj|BAA82535.1| (AB030032) dTDP-4-keto-6-deoxy-D-glucose 3,5-epi... 179 2e-44 sp|P55468|RFBC_RHISN PROBABLE DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERA... 172 3e-42 pir||D82828 dTDP-4-dehydrorhamnose 3,5-epimerase XF0257 [importe... 169 1e-41 gb|AAG09521.1|AF279620_5 (AF279620) dTDP-6-deoxy-D-glucose-3,5-e... 169 1e-41 pir||T15493 hypothetical protein C14F11.6 - Caenorhabditis elega... 166 1e-40 emb|CAC13136.1| (AJ250139) dTDP-4-dehydrorhamnose 3,5-epimerase ... 165 4e-40 pir||S35299 rfbF protein - Yersinia enterocolitica >gi|48590|emb... 162 3e-39 gb|AAG35059.1|AF314183_1 (AF314183) dTDP-rhamnose-3,5-epimerase ... 162 3e-39 pir||D49906 rfbD homolog - Xanthomonas campestris pv. campestris... 161 7e-39 emb|CAB01950.1| (Z79692) ExpA8 [Sinorhizobium meliloti] 159 2e-38 gb|AAC44073.1| (U51197) dTDP-6-deoxy-D-glucose-3,5-epimerase [Sp... 159 2e-38 pir||F72588 probable dTDP-4-dehydrorhamnose 3,5-epimerase APE117... 157 6e-38 pir||S57560 strX protein - Streptomyces glaucescens >gi|2127539|... 157 1e-37 gb|AAK41128.1| dTDP-4-dehydrorhamnose 3,5 epimerase (rfbC-1) [Su... 153 2e-36 emb|CAB57471.1| (Y18930) dTDP-4-dehydrorhamnose 3,5-epimerase (R... 153 2e-36 gb|AAK42118.1| dTDP-4-dehydrorhamnose 3,5 epimerase (rfbC-2) [Su... 150 1e-35 emb|CAB65208.1| (AJ007311) RmlC protein [Legionella pneumophila] 141 7e-33 gb|AAA88702.1| (L33181) CDP-3, 6-dideoxy-D-glycero-D-glycero-4-h... 137 1e-31 gb|AAC60763.1| (U46859) WbcA [Yersinia enterocolitica (type 0:8)] 132 2e-30 gb|AAG29805.1| (AF235050) dTDP-4-keto-6-deoxyglucose 3,5-epimera... 129 3e-29 gb|AAF59933.1| (AF237895) dTDP-4-keto-6-deoxyglucose 3,5-epimera... 127 9e-29 pir||S74752 dTDP-6-deoxy-L-mannose-dehydrogenase - Synechocystis... 127 1e-28 pir||F70566 probable dtdp-4-dehydrorhamnose 3 - Mycobacterium tu... 127 1e-28 emb|CAB39840.1| (AL049491) putative dTDP-4-dehydrorhamnose 3,5-e... 127 1e-28 dbj|BAA84596.1| (AB032523) dTDP-4-keto-6-deoxyhexose 3,5-epimera... 123 1e-27 gb|AAF67516.1|AF170880_23 (AF170880) NovW [Streptomyces spheroides] 122 2e-27 pir||JE0089 dTDP-4-dehydrorhamnose 3,5-epimerase (EC 5.1.3.13) -... 122 3e-27 sp|P29783|STRM_STRGR DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE (DTDP-... 122 4e-27 pir||S44236 dTDP-4-keto-6-deoxyglucose 3,5-epimerase - Streptomy... 121 7e-27 emb|CAB58341.1| (AL121855) putative epimerase [Streptomyces coel... 120 9e-27 pir||T46670 probable 3,5-epimerase nogF [imported] - Streptomyce... 118 6e-26 gb|AAD41820.1|AF147703_6 (AF147703) putative NDP-hexose 3-epimer... 118 6e-26 gb|AAB66649.1| (U43540) rmlC gene product [Mycobacterium tubercu... 113 1e-24 gb|AAD12169.1| (AF055922) epimerase [Streptomyces fradiae] 113 1e-24 gb|AAF70101.1|AF257324_2 (AF257324) AknL [Streptomyces galilaeus] 111 8e-24 gb|AAB84077.1| (U77459) EryBVII [Saccharopolyspora erythraea] >g... 109 3e-23 pir||T30591 conserved hypothetical protein PCZA361.16 - Amycolat... 108 4e-23 gb|AAG13911.1|AF263245_7 (AF263245) TDP-4-keto-6-deoxyhexose 3,5... 108 7e-23 gb|AAC01732.1| (AF040570) dNTP-hexose 3,5 epimerase [Amycolatops... 107 1e-22 pir||T46530 probable dTDP-4-keto-6-deoxyglucose-2,3-dehydratase ... 107 1e-22 gb|AAB63046.1| (AF006633) putative epimerase [Streptomyces peuce... 106 2e-22 pir||S39966 hypothetical protein - Streptomyces griseus >gi|4078... 104 6e-22 gb|AAD13558.1| (AF080235) NDP-hexose 3,5-epimerase homolog [Stre... 101 5e-21 pir||T51104 dTDP-4-keto-6-deoxyglucose 3,5-epimerase [validated]... 101 6e-21 pir||S34962 rfbD protein - Shigella dysenteriae (fragment) >gi|1... 89 5e-17 pir||F81288 probable nucleotide-sugar epimerase/dehydratase Cj14... 86 2e-16 gb|AAF00208.1|AF164960_4 (AF164960) epimerase [Streptomyces frad... 86 3e-16 gb|AAD41825.1|AF147704_5 (AF147704) NDP-hexose 3,5- (or5-) epime... 83 2e-15 gb|AAD10182.1| (AF026471) Cps2M [Streptococcus pneumoniae] 75 8e-13 gb|AAC38694.1| (AF030363) dTDP-4-keto-6-deoxyglucose-3,5-epimera... 72 4e-12 emb|CAB05931.1| (Z83335) dTDP-4-dehydrorhamnose 3,5-epimerase [S... 71 7e-12 gb|AAC44970.1| (U09239) dTDP-4-keto-6-deoxyglucose-3,5-epimerase... 71 9e-12 gb|AAC69539.1| (AF057294) Cps23fP [Streptococcus pneumoniae] 71 9e-12 gb|AAC38705.1| (AF030365) dTDP-4-keto-6-deoxyglucose-3,5-epimera... 71 1e-11 gb|AAC78675.1| (AF094575) dTDP-4-keto-6-deoxyglucose-3,5-epimera... 70 2e-11 gb|AAC38673.1| (AF030359) dTDP-4-keto-6-deoxyglucose-3,5-epimera... 70 2e-11 gb|AAD19914.1| (AF105113) dTDP-4-keto-6-deoxyglucose-3,5-epimera... 69 3e-11 dbj|BAA11248.1| (D78182) dTDP-4-keto-L-rhamnose reductase [Strep... 68 8e-11 >pir||E75098 dTDP-4-dehydrorhamnose 3,5-epimerase (EC 5.1.3.13) PAB0787 - Pyrococcus abyssi (strain Orsay) >gi|5458602|emb|CAB50090.1| (AJ248286) DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE (EC 5.1.3.13) (DTDP-4-KETO-6-DEOXYGLUCOSE 3,5-EPIMERASE) DTDP-L-RHAMNOSE SYNTHETASE). [Pyrococcus abyssi] Length = 185 Score = 390 bits (990), Expect = e-108 Identities = 185/185 (100%), Positives = 185/185 (100%) Query: 1 MPFEFKRLSIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEFVQDNHSRSKYGVLR 60 MPFEFKRLSIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEFVQDNHSRSKYGVLR Sbjct: 1 MPFEFKRLSIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEFVQDNHSRSKYGVLR 60 Query: 61 GLHFQKEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAH 120 GLHFQKEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAH Sbjct: 61 GLHFQKEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAH 120 Query: 121 GFLVLSDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPIDNPILSEKDKKWPTLKELIE 180 GFLVLSDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPIDNPILSEKDKKWPTLKELIE Sbjct: 121 GFLVLSDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPIDNPILSEKDKKWPTLKELIE 180 Query: 181 KDELF 185 KDELF Sbjct: 181 KDELF 185 >pir||A71152 probable dTDP-4-dehydrorhamnose 3,5-epimerase - Pyrococcus horikoshii >gi|3256819|dbj|BAA29502.1| (AP000002) 188aa long hypothetical dTDP-4-dehydrorhamnose 3,5-epimerase [Pyrococcus horikoshii] Length = 188 Score = 351 bits (892), Expect = 3e-96 Identities = 164/185 (88%), Positives = 179/185 (96%) Query: 1 MPFEFKRLSIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEFVQDNHSRSKYGVLR 60 MPFEFKRL IPDV+LIKPKVFEDERGFFMETYKKSDFEKAGIKGEFVQDNHS+SKYGVLR Sbjct: 4 MPFEFKRLEIPDVVLIKPKVFEDERGFFMETYKKSDFEKAGIKGEFVQDNHSKSKYGVLR 63 Query: 61 GLHFQKEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAH 120 GLHFQ+ YAQAKIVRCIRGVI+DVAVDLR+NSPTFGK+VGVILSE+NK+QLYIPRGFAH Sbjct: 64 GLHFQRGSYAQAKIVRCIRGVIYDVAVDLRRNSPTFGKYVGVILSEYNKYQLYIPRGFAH 123 Query: 121 GFLVLSDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPIDNPILSEKDKKWPTLKELIE 180 GF+VLSDVAEVVYKVDNVYAP+YEGGLIWNDPDV IKWPI++PILSEKDKKWPTL+ELIE Sbjct: 124 GFVVLSDVAEVVYKVDNVYAPDYEGGLIWNDPDVGIKWPIEDPILSEKDKKWPTLRELIE 183 Query: 181 KDELF 185 + +F Sbjct: 184 RGWVF 188 >pir||S23343 hypothetical protein 7.0 - Salmonella choleraesuis >gi|46986|emb|CAA43075.1| (X60665) rmlC [Salmonella enterica] Length = 176 Score = 231 bits (583), Expect = 4e-60 Identities = 110/165 (66%), Positives = 132/165 (79%), Gaps = 1/165 (0%) Query: 7 RLSIPDVILIKPKVFEDERGFFMETYKKSDFEKA-GIKGEFVQDNHSRSKYGVLRGLHFQ 65 + IPDV++ +PKVF DERGFFME++ + FE+A G K EFVQDNHS+S GVLRGLH+Q Sbjct: 5 KTEIPDVLIFEPKVFSDERGFFMESFNQKVFEEAVGRKIEFVQDNHSKSTKGVLRGLHYQ 64 Query: 66 KEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVL 125 EPYAQ K+VRCI G +FDVAVD+R +S TFGKWVGV +S NK QL+IP GFAHGFLVL Sbjct: 65 VEPYAQGKLVRCIAGEVFDVAVDIRNDSETFGKWVGVNISSENKRQLWIPEGFAHGFLVL 124 Query: 126 SDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPIDNPILSEKDK 170 S+ AE VYK N Y+ E+E G+IWNDPD+NI W ID+PILS KDK Sbjct: 125 SEEAEFVYKTSNYYSGEHERGIIWNDPDINITWGIDSPILSLKDK 169 >gb|AAG09525.1|AF279621_4 (AF279621) dTDP-6-deoxy-D-glucose-3,5-epimerase [Salmonella enterica] Length = 176 Score = 230 bits (581), Expect = 8e-60 Identities = 111/170 (65%), Positives = 133/170 (77%), Gaps = 1/170 (0%) Query: 7 RLSIPDVILIKPKVFEDERGFFMETYKKSDFEKA-GIKGEFVQDNHSRSKYGVLRGLHFQ 65 + IPDV++ +PKVF DERGFFME++ + FE+A G K EFVQDNHS+S GVLRGLH+Q Sbjct: 5 KTEIPDVLIFEPKVFSDERGFFMESFNQKVFEEAVGPKIEFVQDNHSKSTKGVLRGLHYQ 64 Query: 66 KEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVL 125 EPYAQ K+VRCI G +FDVAVD+RK+S TFGKWVGV LS NK QL+IP GFAHGFLVL Sbjct: 65 VEPYAQGKLVRCIAGEVFDVAVDIRKDSETFGKWVGVNLSSENKRQLWIPEGFAHGFLVL 124 Query: 126 SDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPIDNPILSEKDKKWPTL 175 S+ AE VYK N Y+ E+E G+IWND D+NI W I +PILS KDK P + Sbjct: 125 SEEAEFVYKTSNYYSAEHERGIIWNDTDINITWGIGSPILSLKDKNSPRM 174 >gb|AAG09505.1|AF279616_4 (AF279616) dTDP-6-deoxy-D-glucose-3,5-epimerase [Salmonella enterica] Length = 177 Score = 228 bits (574), Expect = 5e-59 Identities = 108/171 (63%), Positives = 132/171 (77%), Gaps = 2/171 (1%) Query: 7 RLSIPDVILIKPKVFEDERGFFMETYKKSDFEKA-GIKGEFVQDNHSRSKYGVLRGLHFQ 65 + +PDV++ +PKVF DERGFFME++ + FE+A G K EFVQDNHS+S GVLRGLH+Q Sbjct: 5 KTEVPDVLIFEPKVFSDERGFFMESFNQKVFEEAVGRKVEFVQDNHSKSTKGVLRGLHYQ 64 Query: 66 KEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVL 125 EPYAQ K+VRCI G +FDVAVD+RK+S TFGKWVGV +S NK QL+IP GFAHGFLVL Sbjct: 65 VEPYAQGKLVRCIAGEVFDVAVDIRKDSETFGKWVGVNISSENKRQLWIPEGFAHGFLVL 124 Query: 126 SDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWP-IDNPILSEKDKKWPTL 175 + AE VYK N Y P+ + G+ WNDPD+ I WP I+NP+LS KD K P L Sbjct: 125 GEEAEFVYKTSNFYNPDSDRGVAWNDPDIGINWPLINNPLLSNKDSKQPFL 175 >sp|P37780|RFBC_SHIFL DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE (DTDP-4-KETO-6-DEOXYGLUCOSE 3,5-EPIMERASE) (DTDP-L-RHAMNOSE SYNTHETASE) >gi|1073705|pir||E55213 rfbD protein - Shigella flexneri >gi|294899|gb|AAA53682.1| (L14842) dTDP-6-deoxy-L-mannose-dehydrogenase [Shigella flexneri] >gi|454901|emb|CAA50770.1| (X71970) rfbD [Shigella flexneri] Length = 181 Score = 226 bits (570), Expect = 1e-58 Identities = 105/164 (64%), Positives = 131/164 (79%), Gaps = 1/164 (0%) Query: 7 RLSIPDVILIKPKVFEDERGFFMETYKKSDFEKA-GIKGEFVQDNHSRSKYGVLRGLHFQ 65 + IPDV++ +PKVF DERGFFME++ + FE+A G K EFVQDNHS+S GVLRGLH+Q Sbjct: 5 KTEIPDVLIFEPKVFGDERGFFMESFNQKVFEEAVGRKVEFVQDNHSKSTKGVLRGLHYQ 64 Query: 66 KEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVL 125 EPYAQ K+VRC+ G +FDVAVD+RK+SPTFGKWVGV LS NK QL+IP GFAHGF VL Sbjct: 65 LEPYAQGKLVRCVVGEVFDVAVDIRKSSPTFGKWVGVNLSAENKRQLWIPEGFAHGFCVL 124 Query: 126 SDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPIDNPILSEKD 169 SD AE VYK +N Y+ E G++W+D +NI+WP+ NP+LS+KD Sbjct: 125 SDEAEFVYKTNNFYSKMQERGILWSDKSINIEWPVQNPLLSDKD 168 >gb|AAG09540.1|AF279625_4 (AF279625) dTDP-6-deoxy-D-glucose-3,5-epimerase [Salmonella enterica] Length = 179 Score = 224 bits (564), Expect = 7e-58 Identities = 107/169 (63%), Positives = 132/169 (77%), Gaps = 2/169 (1%) Query: 7 RLSIPDVILIKPKVFEDERGFFMETYKKSDFEKA-GIKGEFVQDNHSRSKYGVLRGLHFQ 65 + IPDV++ +PKVF DERGFFME++ + FE+A G K EFVQDNHS+S GVLRGLH+Q Sbjct: 5 KTEIPDVLIFEPKVFSDERGFFMESFNQKVFEEAVGRKIEFVQDNHSKSTKGVLRGLHYQ 64 Query: 66 KEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVL 125 EPYAQ K+VRC G +FDVAVD+RK+S TFGKWVGV +S NK QL+IP GFAHGFLVL Sbjct: 65 VEPYAQGKLVRCTAGEVFDVAVDIRKDSETFGKWVGVNISSENKRQLWIPEGFAHGFLVL 124 Query: 126 SDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPID-NPILSEKDKKWP 173 SD A+ +YK N Y+P +E G++WNDP +NI WPI+ + ILSEKD P Sbjct: 125 SDSADFLYKTSNYYSPVHERGIVWNDPTININWPINIDKILSEKDTILP 173 >gb|AAG09501.1|AF279615_4 (AF279615) dTDP-6-deoxy-D-glucose-3,5-epimerase [Salmonella enterica] Length = 179 Score = 223 bits (562), Expect = 1e-57 Identities = 107/169 (63%), Positives = 132/169 (77%), Gaps = 2/169 (1%) Query: 7 RLSIPDVILIKPKVFEDERGFFMETYKKSDFEKA-GIKGEFVQDNHSRSKYGVLRGLHFQ 65 + IPDV++ +PKVF DERGFFME++ + FE+A G K EFVQDNHS+S GVLRGLH+Q Sbjct: 5 KTEIPDVLIFEPKVFSDERGFFMESFNQKVFEEAVGRKIEFVQDNHSKSTKGVLRGLHYQ 64 Query: 66 KEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVL 125 EPYAQ K+VRCI G +FDVAVD+RK+S TFGKWVGV +S NK L+IP GFAHGFLVL Sbjct: 65 VEPYAQGKLVRCIAGEVFDVAVDIRKDSETFGKWVGVNISSENKRPLWIPEGFAHGFLVL 124 Query: 126 SDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPID-NPILSEKDKKWP 173 SD A+ +YK N Y+P +E G++WNDP +NI WPI+ + ILSEKD P Sbjct: 125 SDSADFLYKTSNYYSPIHERGIVWNDPTININWPINIDKILSEKDTILP 173 >gb|AAG09529.1|AF279622_4 (AF279622) dTDP-6-deoxy-D-glucose-3,5-epimerase [Salmonella enterica] Length = 177 Score = 222 bits (559), Expect = 3e-57 Identities = 106/171 (61%), Positives = 132/171 (76%), Gaps = 2/171 (1%) Query: 7 RLSIPDVILIKPKVFEDERGFFMETYKKSDFEKA-GIKGEFVQDNHSRSKYGVLRGLHFQ 65 + IPDV++ +PKVF DERGFFME++ ++ FE+A G K EFV DNHS+S GVLRGLH+Q Sbjct: 5 KTEIPDVLIFEPKVFSDERGFFMESFNQTVFEEAVGRKIEFVLDNHSKSTKGVLRGLHYQ 64 Query: 66 KEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVL 125 EPYAQ K+VRCI G +FDVAVD+RK+S TFGKW+GV LS NK QL+IP GFAHGFLVL Sbjct: 65 VEPYAQGKLVRCIAGEVFDVAVDIRKDSETFGKWIGVNLSSENKRQLWIPEGFAHGFLVL 124 Query: 126 SDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWP-IDNPILSEKDKKWPTL 175 S+ AE +YK N Y P + G+ WNDP + I WP ++NP+LS+KD K P L Sbjct: 125 SEEAEFLYKTTNFYNPRSDRGVAWNDPYIGINWPLVNNPLLSDKDSKQPFL 175 >gb|AAG09516.1|AF279619_4 (AF279619) dTDP-6-deoxy-D-glucose-3,5-epimerase [Salmonella enterica] Length = 181 Score = 209 bits (527), Expect = 2e-53 Identities = 104/173 (60%), Positives = 128/173 (73%), Gaps = 2/173 (1%) Query: 7 RLSIPDVILIKPKVFEDERGFFMETYKKSDFEKA-GIKGEFVQDNHSRSKYGVLRGLHFQ 65 + IPDV++ +PKVF D+RGFFME++ + F++A G K EFVQDNHS+S GVLRGLH+Q Sbjct: 5 KTDIPDVLIFEPKVFGDKRGFFMESFNQRVFDEALGHKVEFVQDNHSKSSKGVLRGLHYQ 64 Query: 66 KEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVL 125 PYAQ K+VRC+ G +FDVAVD+RK+S TFGKWVGV LS NK QL+IP GFAHGF VL Sbjct: 65 LPPYAQGKLVRCVVGEVFDVAVDIRKDSETFGKWVGVNLSADNKKQLWIPEGFAHGFYVL 124 Query: 126 SDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPIDNPI-LSEKDKKWPTLKE 177 S+ AE++YK N Y + G+IWND +NI WPI I LSEKD TL E Sbjct: 125 SETAELLYKTTNYYNLLSDRGIIWNDRSININWPISGDILLSEKDMNHGTLTE 177 >gb|AAC70776.1| (AF097519) dTDP-4-keto-6-deoxy-D-glucose 3,5-epimerase [Klebsiella pneumoniae] Length = 184 Score = 205 bits (516), Expect = 3e-52 Identities = 97/173 (56%), Positives = 127/173 (73%), Gaps = 4/173 (2%) Query: 7 RLSIPDVILIKPKVFEDERGFFMETYKKSDFEKA-GIKGEFVQDNHSRSKYGVLRGLHFQ 65 + IPDV++ +P+VF D RGFF E++ F +A G + EFVQDNHS+S+ GVLRGLH+Q Sbjct: 5 KTDIPDVLIFEPRVFGDARGFFFESFSSKVFNEAVGRQVEFVQDNHSQSQKGVLRGLHYQ 64 Query: 66 KEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVL 125 +P+AQ K+VRC+ G +FDVAVD+R++SPTFGKWVG +LS NK QL+IP GFAHGF+ L Sbjct: 65 LDPHAQGKLVRCVEGEVFDVAVDIRRSSPTFGKWVGAVLSAENKRQLWIPEGFAHGFMAL 124 Query: 126 SDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPIDNPI---LSEKDKKWPTL 175 SD + VYK N YAP+ E +IWNDP++ I WP + LSEKD + TL Sbjct: 125 SDTVQFVYKGTNYYAPQSERSIIWNDPEIGIDWPALSDCVLSLSEKDLRAHTL 177 >sp|P26394|RFBC_SALTY DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE (DTDP-4-KETO-6-DEOXYGLUCOSE 3,5-EPIMERASE) (DTDP-L-RHAMNOSE SYNTHETASE) >gi|96786|pir||S15302 hypothetical protein 7.0 - Salmonella typhimurium >gi|7767043|pdb|1DZR|A Chain A, Rmlc From Salmonella Typhimurium >gi|7767044|pdb|1DZR|B Chain B, Rmlc From Salmonella Typhimurium >gi|7767045|pdb|1DZT|A Chain A, Rmlc From Salmonella Typhimurium >gi|7767046|pdb|1DZT|B Chain B, Rmlc From Salmonella Typhimurium >gi|581655|emb|CAA40118.1| (X56793) dTDP-6-deoxy-D-glucose-3,5 epimerase [Salmonella enterica] Length = 183 Score = 204 bits (513), Expect = 7e-52 Identities = 99/175 (56%), Positives = 125/175 (70%), Gaps = 2/175 (1%) Query: 7 RLSIPDVILIKPKVFEDERGFFMETYKKSDFEKA-GIKGEFVQDNHSRSKYGVLRGLHFQ 65 + +IPDV++++PKVF DERGFF E+Y + FE+ G K FVQDNHS+SK VLRGLHFQ Sbjct: 6 KTAIPDVLILEPKVFGDERGFFFESYNQQTFEELIGRKVTFVQDNHSKSKKNVLRGLHFQ 65 Query: 66 KEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVL 125 + AQ K+VRC G +FDVAVD+RK SPTFG+WVGV LS NK QL+IP GFAHGF+ L Sbjct: 66 RGENAQGKLVRCAVGEVFDVAVDIRKESPTFGQWVGVNLSAENKRQLWIPEGFAHGFVTL 125 Query: 126 SDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPIDN-PILSEKDKKWPTLKELI 179 S+ AE +YK N Y+P EG ++WND + I+WP P LS KD P L + + Sbjct: 126 SEYAEFLYKATNYYSPSSEGSILWNDEAIGIEWPFSQLPELSAKDAAAPLLDQAL 180 >sp|P37745|RFBC_ECOLI DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE (DTDP-4-KETO-6-DEOXYGLUCOSE 3,5-EPIMERASE) (DTDP-L-RHAMNOSE SYNTHETASE) >gi|2121109|pir||I69651 dTDP-4-dehydrorhamnose 3,5-epimerase (EC 5.1.3.13) - Escherichia coli (strain K-12) >gi|508240|gb|AAB88401.1| (U09876) dTDP-6-deoxy-D-glucose-3,5 epimerase [Escherichia coli] >gi|510251|gb|AAC31630.1| (U03041) dTDP-6-deoxy-L-xylo-4-hexulose 4-reductase [Escherichia coli] >gi|1736728|dbj|BAA15880.1| (D90841) dTDP-4-dehydrorhamnose 3,5-epimerase (EC 5.1.3.13) (dTDP-4-keto-6- deoxyglucose 3,5-epimerase) (dTDP-L-rhamnose synthetase). [Escherichia coli] >gi|1736741|dbj|BAA15892.1| (D90842) dTDP-4-dehydrorhamnose 3,5-epimerase (EC 5.1.3.13) (dTDP-4-keto-6- deoxyglucose 3,5-epimerase) (dTDP-L-rhamnose synthetase). [Escherichia coli] >gi|1788350|gb|AAC75099.1| (AE000294) dTDP-6-deoxy-D-glucose-3,5 epimerase [Escherichia coli K12] Length = 185 Score = 203 bits (511), Expect = 1e-51 Identities = 102/175 (58%), Positives = 125/175 (71%), Gaps = 2/175 (1%) Query: 7 RLSIPDVILIKPKVFEDERGFFMETYKKSDFEKA-GIKGEFVQDNHSRSKYGVLRGLHFQ 65 R I DV++++P+VF D+RGFF E++ +S FE G FVQDNHSRS VLRGLHFQ Sbjct: 5 RTEIEDVLILEPRVFGDDRGFFYESFNQSAFEHILGYPVSFVQDNHSRSSKNVLRGLHFQ 64 Query: 66 KEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVL 125 + YAQ K+VRC G +FDVAVD+R NS +FGKWVGV+LS NK QL+IP+GFAHGFLVL Sbjct: 65 RGEYAQDKLVRCTHGAVFDVAVDIRPNSVSFGKWVGVLLSADNKQQLWIPKGFAHGFLVL 124 Query: 126 SDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWP-IDNPILSEKDKKWPTLKELI 179 SD+AE YK N Y PE + G+ WND + I WP ILS KD++ TL ELI Sbjct: 125 SDIAEFQYKTTNYYHPESDCGICWNDERIAIDWPQTSGLILSPKDERLFTLDELI 179 >pir||B69106 dTDP-4-dehydrorhamnose 3,5-epimerase - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622921|gb|AAB86256.1| (AE000933) dTDP-4-dehydrorhamnose 3,5-epimerase [Methanobacterium thermoautotrophicum] Length = 185 Score = 203 bits (510), Expect = 2e-51 Identities = 97/178 (54%), Positives = 129/178 (71%), Gaps = 4/178 (2%) Query: 3 FEFKRLSIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEFVQDNHSRSKYGVLRGL 62 F F + S+ I+I+P+V+ DERG+FMET+ ++ F++ G++ FVQDN S S GVLRGL Sbjct: 4 FRFIKTSLDGAIIIEPEVYTDERGYFMETFNEAIFQENGLEVRFVQDNESMSVRGVLRGL 63 Query: 63 HFQKEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGF 122 HFQ+E Q K+VR IRG IFDVAVDLRKNS T+G+W GV LS+ N+ + +IP GFAHGF Sbjct: 64 HFQREK-PQGKLVRVIRGEIFDVAVDLRKNSDTYGEWTGVRLSDENRREFFIPEGFAHGF 122 Query: 123 LVLSDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWP---IDNPILSEKDKKWPTLKE 177 L LSD V YK +Y PEY+ G+ W+DPD+ I WP +D+ I+SEKD+ W L+E Sbjct: 123 LALSDECIVNYKCTELYHPEYDSGIPWDDPDIGIDWPLEMVDDLIISEKDRNWKPLRE 180 >pir||E83000 dTDP-4-dehydrorhamnose 3,5-epimerase PA5164 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9951466|gb|AAG08549.1|AE004929_4 (AE004929) dTDP-4-dehydrorhamnose 3,5-epimerase [Pseudomonas aeruginosa] Length = 181 Score = 199 bits (501), Expect = 2e-50 Identities = 99/167 (59%), Positives = 127/167 (75%), Gaps = 3/167 (1%) Query: 7 RLSIPDVILIKPKVFEDERGFFMETYKKSDFEKA-GIKGEFVQDNHSRSKYGVLRGLHFQ 65 RL+IPDVIL +P+VF D+RGFF E+Y + FE+A G FVQDNHSRS GVLRGLH+Q Sbjct: 5 RLAIPDVILFEPRVFGDDRGFFFESYNQRAFEEACGHPVSFVQDNHSRSARGVLRGLHYQ 64 Query: 66 KEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVL 125 AQ K+VR G +FDVAVDLR+ SPTFG+WVG LS NK Q++IP GFAHGF+VL Sbjct: 65 IRQ-AQGKLVRATLGEVFDVAVDLRRGSPTFGQWVGERLSAENKRQMWIPAGFAHGFVVL 123 Query: 126 SDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPI-DNPILSEKDKK 171 S+ AE +YK + +APE+E ++WNDP++ I WP+ D P+LSEKD++ Sbjct: 124 SEYAEFLYKTTDFWAPEHERCIVWNDPELKIDWPLQDAPLLSEKDRQ 170 >gb|AAD40710.1|AF048749_6 (AF048749) dTDP-6-deoxy-D-glucose-3,5 epimerase [Bacteroides fragilis] Length = 182 Score = 198 bits (499), Expect = 3e-50 Identities = 93/175 (53%), Positives = 128/175 (73%), Gaps = 2/175 (1%) Query: 7 RLSIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEFVQDNHSRSKYGVLRGLHFQK 66 + +I +++++P++F+D+RG+F E++ + +FE+ K FVQDN S+S YGV+RGLHFQK Sbjct: 5 KTAIEGLVILEPQLFKDDRGYFFESFNQREFEEKVCKTTFVQDNESKSSYGVIRGLHFQK 64 Query: 67 EPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVLS 126 P+AQ+K+VR I+G + DVAVD+RK SPTFGK V V L+E N Q +IPRGFAHGF VLS Sbjct: 65 PPFAQSKLVRVIKGAVLDVAVDIRKGSPTFGKHVSVELTEDNHRQFFIPRGFAHGFSVLS 124 Query: 127 DVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKW--PIDNPILSEKDKKWPTLKELI 179 + YK DN Y PE EG + WNDPD+ I+W P + ILS+KD+ P LK +I Sbjct: 125 EEVIFQYKCDNFYHPEAEGAIAWNDPDLGIEWRVPCKSIILSKKDRVHPLLKYII 179 >pir||S78545 dTDP-4-dehydrorhamnose 3,5-epimerase (EC 5.1.3.13) - Escherichia coli (strain VW187) >gi|799235|gb|AAC63615.1| (AF125322) RmlC [Escherichia coli] Length = 183 Score = 196 bits (493), Expect = 2e-49 Identities = 98/178 (55%), Positives = 129/178 (72%), Gaps = 3/178 (1%) Query: 7 RLSIPDVILIKPKVFEDERGFFMETYKKSDFEKA-GIKGEFVQDNHSRSKYGVLRGLHFQ 65 + IPDV++ +PKVF DERGFFME++ + FE+A G K EFVQDNHS+S GV+RGLHFQ Sbjct: 5 KTEIPDVLIFEPKVFGDERGFFMESFNQKVFEEAVGRKVEFVQDNHSKSTKGVIRGLHFQ 64 Query: 66 KEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVI-LSEFNKWQLYIPRGF-AHGFL 123 PY+QAK+VRC+ G ++DV VD+RK+S TFGKWV ++ LS NK QL+IP GF +HGF Sbjct: 65 LPPYSQAKLVRCVVGEVYDVVVDIRKDSKTFGKWVRLVNLSAENKRQLWIPEGFGSHGFE 124 Query: 124 VLSDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPIDNPILSEKDKKWPTLKELIEK 181 V+S+VA +YK +N Y E G+ W+D + I W I+SEKD K P+ +EL EK Sbjct: 125 VISEVASFLYKTNNYYNATMEKGIRWDDEYLAINWKEKKAIISEKDMKQPSFRELFEK 182 >pir||S76461 hypothetical protein - Synechocystis sp. (strain PCC 6803) >gi|1653678|dbj|BAA18590.1| (D90915) dTDP-4-dehydrorhamnose 3,5-epimerase [Synechocystis sp.] Length = 182 Score = 195 bits (491), Expect = 3e-49 Identities = 97/171 (56%), Positives = 127/171 (73%), Gaps = 3/171 (1%) Query: 9 SIPDVILIKPKVFEDERGFFMETYKKSDFEKA-GIKGEFVQDNHSRSKYGVLRGLHFQKE 67 +I DV++++PKVF DERGFF E+Y F++A GI+ FVQDNHS S+ GV+RGLH+Q + Sbjct: 7 TIADVLILEPKVFGDERGFFFESYNDKVFQQAVGIEPHFVQDNHSFSRQGVVRGLHYQIQ 66 Query: 68 PYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVLSD 127 + Q K+VR RG IFDVAVDLR+NSP+FG+WVG +L++ NK QL+IP GFAHGF VLS Sbjct: 67 -HPQGKLVRVARGEIFDVAVDLRRNSPSFGQWVGCVLNDHNKRQLWIPAGFAHGFAVLSP 125 Query: 128 VAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPI-DNPILSEKDKKWPTLKE 177 AEV+YK + YAP YE L+WNDP + I W + P+LS KD++ L E Sbjct: 126 EAEVLYKATDYYAPSYERTLLWNDPAIGIDWSLTTTPLLSLKDQRGLPLAE 176 >pir||A82013 dTDP-4-dehydrorhamnose 3,5-epimerase (EC 5.1.3.13) NMA0187 [similarity] - Neisseria meningitidis (group A strain Z2491) >gi|7378959|emb|CAB83502.1| (AL162752) dTDP-D-glucose 4,6-dehydratase [Neisseria meningitidis Z2491] Length = 184 Score = 194 bits (488), Expect = 6e-49 Identities = 99/172 (57%), Positives = 120/172 (69%), Gaps = 2/172 (1%) Query: 9 SIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEFVQDNHSRSKYGVLRGLHFQKEP 68 +IPDV L++P+VF D RGFFMET++ F+ FVQ+NHS+S GVLRGLH+Q E Sbjct: 12 AIPDVKLLEPQVFGDARGFFMETFRDEWFKTQVCNRTFVQENHSKSGKGVLRGLHYQTEN 71 Query: 69 YAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVLSDV 128 Q K+VR + G +FDVAVD+RK+SPTFGKWVG ILS NK QL++P GFAHGF VL D Sbjct: 72 -TQGKLVRVVVGEVFDVAVDMRKDSPTFGKWVGEILSAENKRQLWVPEGFAHGFCVLGDA 130 Query: 129 AEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPIDN-PILSEKDKKWPTLKELI 179 AEVVYK + Y PE E LIWNDP V I WP+ P+LS KD L E + Sbjct: 131 AEVVYKCTDYYKPEAEQVLIWNDPTVGIGWPLQTAPLLSPKDLAGKVLAEAV 182 >pir||A82015 dTDP-4-dehydrorhamnose 3,5-epimerase (EC 5.1.3.13) NMA0206 [imported] - Neisseria meningitidis (group A strain Z2491) >gi|7378975|emb|CAB83520.1| (AL162752) dTDP-4-dehydrorhamnose 3,5-epimerase [Neisseria meningitidis Z2491] Length = 190 Score = 194 bits (488), Expect = 6e-49 Identities = 100/174 (57%), Positives = 122/174 (69%), Gaps = 5/174 (2%) Query: 9 SIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEFVQDNHSRSKYGVLRGLHFQKEP 68 +IPDV L++P+VF D RGFFMET++ F+ FVQ+NHS+S GVLRGLH+Q E Sbjct: 12 AIPDVKLLEPQVFGDARGFFMETFRDEWFKTQVCNRTFVQENHSKSGKGVLRGLHYQTEN 71 Query: 69 YAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVLSDV 128 Q K+VR + G +FDVAVD+RK+SPTFGKWVG ILS NK QL++P GFAHGF VL D Sbjct: 72 -TQGKLVRVVVGEVFDVAVDMRKDSPTFGKWVGEILSAENKRQLWVPEGFAHGFCVLGDA 130 Query: 129 AEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPIDN-PILSEKD---KKWPTLKEL 178 AEVVYK + Y PE E LIWNDP V I WP+ P+LS KD K W ++L Sbjct: 131 AEVVYKCTDYYKPEAEQVLIWNDPTVGIGWPLQTAPLLSPKDLAGKTWAQAEKL 184 >gb|AAG09512.1|AF279618_4 (AF279618) dTDP-6-deoxy-D-glucose-3,5-epimerase [Salmonella enterica] Length = 182 Score = 192 bits (483), Expect = 2e-48 Identities = 97/166 (58%), Positives = 118/166 (70%), Gaps = 4/166 (2%) Query: 10 IPDVILIKPKVFEDERGFFMETYKKSDFEKA-GIKGEFVQDNHSRSKYGVLRGLHFQKEP 68 IPDV +++P VF DERGFFME++ FE IK FVQDNHS+S V+RGLH+Q EP Sbjct: 8 IPDVFILEPLVFVDERGFFMESFNHRVFETLLDIKVNFVQDNHSKSTKNVVRGLHYQTEP 67 Query: 69 YAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVLSDV 128 YAQ K+VRCI G ++DVAVDLR S T+G WVGV LS N QL+IP GFAHGFL L+D Sbjct: 68 YAQGKLVRCISGAVYDVAVDLRSTSQTYGCWVGVELSALNMRQLWIPEGFAHGFLTLTDN 127 Query: 129 AEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPI---DNPILSEKDKK 171 E +YK N Y E E + +NDPD++I WPI DN I+S+KDKK Sbjct: 128 VEFLYKTTNYYNKESERCIRYNDPDLDIIWPISNKDNIIVSDKDKK 173 >gb|AAC37051.1| (L09189) rfbC gene product [Neisseria meningitidis] Length = 333 Score = 191 bits (481), Expect = 4e-48 Identities = 99/172 (57%), Positives = 120/172 (69%), Gaps = 5/172 (2%) Query: 9 SIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEFVQDNHSRSKYGVLRGLHFQKEP 68 +IPDV L++P+VF D RGFFMET++ F+ + FVQ+NHS+S GVLRGLH+Q E Sbjct: 12 AIPDVKLLEPQVFGDARGFFMETFRDEWFKTQVCERTFVQENHSKSGKGVLRGLHYQTEN 71 Query: 69 YAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVLSDV 128 Q K+VR + G +FDVAVD+R+ SPTFGKWVG ILS N+ QL+IP GFAHGF VL D Sbjct: 72 -TQGKLVRVVVGEVFDVAVDMREGSPTFGKWVGEILSAQNQCQLWIPEGFAHGFCVLGDA 130 Query: 129 AEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPIDN-PILSEKD---KKWPTLK 176 AEVVYK + Y PE E LIWNDP V I WP+ P+LS KD K W K Sbjct: 131 AEVVYKCTDYYKPEAEQVLIWNDPTVGIGWPLQTAPLLSPKDLAGKAWAQAK 182 >pir||C81240 dTDP-4-keto-6-deoxy-D-glucose-3,6-epimerase NMB0081 [imported] - Neisseria meningitidis (group B strain MD58) >gi|7225299|gb|AAF40545.1| (AE002367) dTDP-4-keto-6-deoxy-D-glucose-3,6-epimerase [Neisseria meningitidis MC58] Length = 184 Score = 191 bits (481), Expect = 4e-48 Identities = 98/172 (56%), Positives = 120/172 (68%), Gaps = 2/172 (1%) Query: 9 SIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEFVQDNHSRSKYGVLRGLHFQKEP 68 +IPDV L++P+VF D RGFFMET++ F+ + FVQ+NHS+S GVLRGLH+Q E Sbjct: 12 AIPDVKLLEPQVFGDARGFFMETFRDEWFKTQVCERTFVQENHSKSGKGVLRGLHYQTEN 71 Query: 69 YAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVLSDV 128 Q K+VR + G +FDVAVD+RK+SPTFGKWVG ILS NK QL++P GFAHGF VLSD Sbjct: 72 -TQGKLVRVVVGEVFDVAVDMRKDSPTFGKWVGEILSAENKRQLWVPEGFAHGFYVLSDE 130 Query: 129 AEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPID-NPILSEKDKKWPTLKELI 179 AE VYK + Y P+ E LIWNDP V I WP+ P LS KD L E + Sbjct: 131 AEFVYKCTDYYNPKAEHSLIWNDPTVGIDWPLQGEPNLSPKDLAGKVLSEAV 182 >pir||T31086 probable dTDP-4-dehydrorhamnose 3,5 epimerase - Serratia marcescens >gi|2828670|gb|AAC00178.1| (AF038816) putative dTDP-4-dehydrorhamnose 3,5 epimerase [Serratia marcescens] Length = 177 Score = 189 bits (475), Expect = 2e-47 Identities = 93/170 (54%), Positives = 121/170 (70%), Gaps = 2/170 (1%) Query: 10 IPDVILIKPKVFEDERGFFMETYKKSDFEKA-GIKGEFVQDNHSRSKYGVLRGLHFQKEP 68 + V LI+PKVF D+RGFF+ET++KS +++ GI EFVQDNHSRS GVLRGLHFQ Sbjct: 8 VEGVKLIEPKVFGDQRGFFLETFQKSRYQELLGIDAEFVQDNHSRSARGVLRGLHFQTAK 67 Query: 69 YAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVLSDV 128 Q K+VR +RG ++DV VD+R SPTF K VGV LSE NK QL++P G AHGF+V+SD Sbjct: 68 -PQGKLVRVVRGEVYDVVVDIRPESPTFKKRVGVYLSEENKNQLWVPPGLAHGFVVVSDS 126 Query: 129 AEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPIDNPILSEKDKKWPTLKEL 178 + YK + Y P EG L+WNDP+V ++WP+ P+LS KD + +EL Sbjct: 127 VDFEYKCTDYYDPSNEGCLLWNDPEVGVEWPVSEPLLSPKDLQGKLFREL 176 >sp|P37763|RFBC_NEIGO DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE (DTDP-4-KETO-6-DEOXYGLUCOSE 3,5-EPIMERASE) (DTDP-L-RHAMNOSE SYNTHETASE) >gi|628589|pir||S47047 dTDP-4-dehydrorhamnose 3,5-epimerase (EC 5.1.3.13) - Neisseria gonorrhoeae >gi|520898|emb|CAA83654.1| (Z32742) dTDP-6-deoxy-L-mannose-dehydrogenase [Neisseria gonorrhoeae] >gi|1333795|emb|CAA79720.1| (Z21508) rfbC [Neisseria gonorrhoeae] Length = 328 Score = 189 bits (474), Expect = 3e-47 Identities = 95/168 (56%), Positives = 117/168 (69%), Gaps = 5/168 (2%) Query: 9 SIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEFVQDNHSRSKYGVLRGLHFQKEP 68 ++PDV L+KP+VF D RGFFMET++ F++ FVQ+NHS S GVLRGLH+Q E Sbjct: 7 ALPDVKLLKPQVFTDGRGFFMETFRDGWFKENIADRTFVQENHSNSSKGVLRGLHYQTEN 66 Query: 69 YAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVLSDV 128 Q K+VR + G +FDVAVD+R+ SPTFGKW G LS N++QL+IP GFAHGF VL D Sbjct: 67 -TQGKLVRVVVGEVFDVAVDMREGSPTFGKWAGATLSAQNRYQLWIPEGFAHGFCVLGDA 125 Query: 129 AEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPIDN-PILSEKD---KKW 172 AEVVYK + Y PE E LIWNDP + I WP+ P+LS KD K W Sbjct: 126 AEVVYKCTDYYNPETEQVLIWNDPAIGIGWPLQTAPLLSPKDLAGKTW 173 >pir||S42433 TDP-deoxyglucose epimerase - Neisseria meningitidis >gi|388935|gb|AAA63159.1| (L09188) TDP-deoxyglucose-epimerase [Neisseria meningitidis] Length = 180 Score = 188 bits (473), Expect = 4e-47 Identities = 94/172 (54%), Positives = 119/172 (68%), Gaps = 2/172 (1%) Query: 9 SIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEFVQDNHSRSKYGVLRGLHFQKEP 68 ++PDV ++KP+VF+D RGFFMET++ F++ FVQ+NHS+S GVLRGLH+Q E Sbjct: 7 ALPDVKILKPQVFKDGRGFFMETFRDGWFKENIADCSFVQENHSKSGKGVLRGLHYQTEN 66 Query: 69 YAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVLSDV 128 Q K+VR + G +FDVAVD+R+ SPTFGKW G LS N++QL+IP GFAHGF VL D Sbjct: 67 -TQGKLVRVVVGEVFDVAVDMREGSPTFGKWTGATLSAQNQYQLWIPEGFAHGFCVLGDA 125 Query: 129 AEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPID-NPILSEKDKKWPTLKELI 179 AEVVYK + Y P+ E LIWNDP V I WP+ P LS KD L E + Sbjct: 126 AEVVYKCTDYYNPKAEHSLIWNDPTVGIDWPLQGEPNLSPKDLAGKVLAEAV 177 >gb|AAG09533.1|AF279623_4 (AF279623) dTDP-6-deoxy-D-glucose-3,5-epimerase [Salmonella enterica] Length = 182 Score = 188 bits (473), Expect = 4e-47 Identities = 95/166 (57%), Positives = 117/166 (70%), Gaps = 4/166 (2%) Query: 10 IPDVILIKPKVFEDERGFFMETYKKSDFEKA-GIKGEFVQDNHSRSKYGVLRGLHFQKEP 68 IPDV +++P VF +ERGFFME++ FE K FVQDNHS+S V+RGLH+Q EP Sbjct: 8 IPDVFILEPLVFVNERGFFMESFNHRVFETLLDTKVNFVQDNHSKSTKNVVRGLHYQTEP 67 Query: 69 YAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVLSDV 128 YAQ K+VRCI G ++DVAVDLR S T+G WVGV LS N QL+IP GFAHGFL L+D Sbjct: 68 YAQGKLVRCISGAVYDVAVDLRSTSQTYGCWVGVELSALNMRQLWIPEGFAHGFLTLTDN 127 Query: 129 AEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPI---DNPILSEKDKK 171 E +YK N Y E E + +NDPD++I WPI DN I+S+KDKK Sbjct: 128 VEFLYKTTNYYNKESERCIRYNDPDLDIIWPISNKDNIIVSDKDKK 173 >pir||T00105 dTDP-4-keto-6-deoxy-D-glucose-3,6-epimerase (EC 5.1.3.-) - Actinobacillus actinomycetemcomitans >gi|3132257|dbj|BAA28134.1| (AB010415) dTDP-4-keto-6-deoxy-D-glucose-3,6-epimerase [Actinobacillus actinomycetemcomitans] Length = 180 Score = 187 bits (470), Expect = 8e-47 Identities = 95/171 (55%), Positives = 119/171 (69%), Gaps = 2/171 (1%) Query: 10 IPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEFVQDNHSRSKYGVLRGLHFQKEPY 69 IPDV L++ +VF DERGFFMET++ F + FVQ+NHS+S GVLRGLH+Q E Sbjct: 8 IPDVKLLELQVFGDERGFFMETFRDEWFRENVADHTFVQENHSKSIKGVLRGLHYQTEN- 66 Query: 70 AQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVLSDVA 129 Q K+VR + G +FDVAVD+RKNSPTFG+WVG ILS NK QL++P GFAHGF VL+D A Sbjct: 67 TQGKLVRVVSGAVFDVAVDMRKNSPTFGQWVGEILSAENKRQLWVPEGFAHGFYVLTDEA 126 Query: 130 EVVYKVDNVYAPEYEGGLIWNDPDVNIKWPID-NPILSEKDKKWPTLKELI 179 E YK + Y P+ E LIWND V I+WP++ P LS KD LK+ + Sbjct: 127 EFTYKCTDYYNPKAEHSLIWNDETVGIEWPLEGEPSLSAKDLAGKVLKDAV 177 >dbj|BAA94405.1| (AB041266) dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase [Actinobacillus actinomycetemcomitans] Length = 180 Score = 184 bits (462), Expect = 7e-46 Identities = 92/161 (57%), Positives = 114/161 (70%), Gaps = 2/161 (1%) Query: 10 IPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEFVQDNHSRSKYGVLRGLHFQKEPY 69 IPDV L++P+VF DERGFFMET++ F K FVQ+NHS+S GVLRGLH+Q E Sbjct: 8 IPDVKLLEPQVFGDERGFFMETFRDEWFRKNVADRTFVQENHSKSIKGVLRGLHYQTEN- 66 Query: 70 AQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVLSDVA 129 Q K+VR + G +FDVAVD+R+NSPTFG+WVG +LS NK QL++P GFAHGF VL+ A Sbjct: 67 TQGKLVRVVSGAVFDVAVDMRENSPTFGQWVGEVLSAENKHQLWVPEGFAHGFYVLTGEA 126 Query: 130 EVVYKVDNVYAPEYEGGLIWNDPDVNIKWPI-DNPILSEKD 169 E YK + Y P+ E LIWND V I+WP+ P LS KD Sbjct: 127 EFTYKCTDYYNPKAEYSLIWNDETVGIEWPLYGEPSLSAKD 167 >dbj|BAA19636.1| (AB002668) dTDP-4-keto-6-deoxy-D-glucose-3,5-epimerase [Actinobacillus actinomycetemcomitans] Length = 179 Score = 183 bits (461), Expect = 9e-46 Identities = 95/172 (55%), Positives = 117/172 (67%), Gaps = 2/172 (1%) Query: 10 IPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEFVQDNHSRSKYGVLRGLHFQKEPY 69 IPDV L++P+VF DERGFFMET++ F K FVQ+NHS+S GVLRGLH+Q E Sbjct: 8 IPDVKLLEPQVFGDERGFFMETFRDEWFRKNVADRIFVQENHSKSIKGVLRGLHYQTEN- 66 Query: 70 AQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVLSDVA 129 Q K+VR I G +FDVAVD+R NS TFG+WVG ILS NK QL++P GFAHGF VL+D A Sbjct: 67 TQGKLVRVISGAVFDVAVDMRGNSLTFGQWVGEILSAENKHQLWVPEGFAHGFYVLTDEA 126 Query: 130 EVVYKVDNVYAPEYEGGLIWNDPDVNIKWPI-DNPILSEKDKKWPTLKELIE 180 E YK + Y P+ E LIWND + I+WP+ P LS KD L E ++ Sbjct: 127 EFTYKCTDYYNPKAEHSLIWNDETIGIEWPLYGEPSLSAKDLAGKVLAETVK 178 >gb|AAD05456.1| (AF064070) putative dTDP-4-keto-6-deoxy-D-glucose 3,5-epimerase [Burkholderia pseudomallei] Length = 183 Score = 183 bits (460), Expect = 1e-45 Identities = 89/179 (49%), Positives = 126/179 (69%), Gaps = 3/179 (1%) Query: 1 MPFEFKRLSIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKG-EFVQDNHSRSKYGVL 59 M + ++P+V +I+PKVF D RGFF E++ +F + G EFVQDNHSRS GVL Sbjct: 1 MAIQVTATALPEVKIIEPKVFGDARGFFFESFNAREFTELVEPGIEFVQDNHSRSARGVL 60 Query: 60 RGLHFQKEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFA 119 RGLH+Q + +AQ K+VR + G +FDVAVD+R++SP FGKWVGV LS NK QL++P GFA Sbjct: 61 RGLHYQIQ-HAQGKLVRVVDGEVFDVAVDVRRSSPNFGKWVGVRLSAENKRQLWVPAGFA 119 Query: 120 HGFLVLSDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPID-NPILSEKDKKWPTLKE 177 HGF+VLS+ A+ +YK + + PE+E ++W+D + I+WPID P+++ KD + E Sbjct: 120 HGFVVLSESADFLYKTTDYWYPEFERSILWSDKQIGIEWPIDREPLVAAKDAAGKAISE 178 >gb|AAD12969.1| (AF078135) RmlC [Leptospira borgpetersenii] Length = 186 Score = 183 bits (459), Expect = 2e-45 Identities = 91/176 (51%), Positives = 114/176 (64%), Gaps = 4/176 (2%) Query: 4 EFKRLSIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEFVQDNHSRSKYGVLRGLH 63 +FKR SI +LIKPKVF DERGFF ET+K S FE I F QDNHSRS GVLRG+H Sbjct: 2 QFKRFSIEGPVLIKPKVFGDERGFFFETFKTSLFESESIPTHFSQDNHSRSSRGVLRGMH 61 Query: 64 FQKEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFL 123 Q PY Q K+VR +RG + DV VD+R SP +GKW V LSE NK ++P GFAHGFL Sbjct: 62 LQVPPYEQGKLVRVVRGKVIDVVVDVRIGSPNYGKWFSVELSEENKNIFWVPPGFAHGFL 121 Query: 124 VLSDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPI----DNPILSEKDKKWPTL 175 L D + +YKV Y+P+ E G+ W+DP + I W I+S++D++ P L Sbjct: 122 TLEDKTDFLYKVTKEYSPQNEVGIRWDDPTLGIPWKTWLSDSEFIVSQRDQETPFL 177 >gb|AAC35921.1| (AF071085) dTDP-4-dehydrorhamnose 3,5-epimerase [Enterococcus faecalis] Length = 190 Score = 180 bits (453), Expect = 8e-45 Identities = 90/169 (53%), Positives = 116/169 (68%), Gaps = 3/169 (1%) Query: 12 DVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEFVQDNHSRS-KYGVLRGLHFQKEPYA 70 DV +I+ VF D RGFF E+Y K+ F + G+ +FVQDNHS S + GVLRGLHFQK A Sbjct: 10 DVKIIEMDVFGDHRGFFTESYSKAKFAEHGLDFDFVQDNHSLSTEAGVLRGLHFQKGEAA 69 Query: 71 QAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVLSDVAE 130 Q K++R + G + DV VD+RK SPT+G+W G ILSE N QL +P+GFAHGF+ L+ Sbjct: 70 QTKLIRVVTGAVLDVIVDIRKGSPTYGQWEGYILSEHNHRQLLVPKGFAHGFVTLTPNVN 129 Query: 131 VVYKVDNVYAPEYEGGLIWNDPDVNIKWPI--DNPILSEKDKKWPTLKE 177 +YK DN Y +GG+ +NDP + I WPI + I SEKD+K PTLKE Sbjct: 130 FMYKCDNYYNAAADGGIAFNDPALAIDWPIAPEKAITSEKDQKHPTLKE 178 >gb|AAB47840.1| (U61226) RfbD [Leptospira interrogans] >gi|5814318|gb|AAD52186.1|AF144879_25 (AF144879) unknown [Leptospira interrogans] Length = 186 Score = 180 bits (452), Expect = 1e-44 Identities = 88/174 (50%), Positives = 115/174 (65%), Gaps = 4/174 (2%) Query: 4 EFKRLSIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEFVQDNHSRSKYGVLRGLH 63 +FK+ I +LI+PKVF DERGFF+ET+K S FEK I +F QDNHSRS GVLRG+H Sbjct: 2 QFKKFQIEGPVLIEPKVFGDERGFFLETFKASIFEKENIPFQFSQDNHSRSSRGVLRGMH 61 Query: 64 FQKEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFL 123 Q PY Q K+VR +RG + DV VD+R SP +GKW+ V LSE NK ++P GFAHGFL Sbjct: 62 LQIPPYDQGKLVRVVRGKVIDVVVDVRVGSPNYGKWLSVELSEENKNIFWVPPGFAHGFL 121 Query: 124 VLSDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPI----DNPILSEKDKKWP 173 L D + +YKV Y+P+ E G+ W+DP + I W I+S++D+ P Sbjct: 122 TLEDKTDFLYKVTGEYSPQNEVGIRWDDPALGIPWKTWLSDSEFIVSQRDQVTP 175 >dbj|BAA82535.1| (AB030032) dTDP-4-keto-6-deoxy-D-glucose 3,5-epimerase [Actinobacillus actinomycetemcomitans] Length = 179 Score = 179 bits (450), Expect = 2e-44 Identities = 93/172 (54%), Positives = 116/172 (67%), Gaps = 2/172 (1%) Query: 10 IPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEFVQDNHSRSKYGVLRGLHFQKEPY 69 IPDV L++ +VF DERGFFMET++ F + FVQ+NHS+S GVLRGLH+Q E Sbjct: 8 IPDVKLLELQVFGDERGFFMETFRDEWFRENVADRTFVQENHSKSIKGVLRGLHYQTEN- 66 Query: 70 AQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVLSDVA 129 Q K+VR I G +FDVAVD+R+NS TFG+WVG +LS NK QL++P GFAHGF VL+D A Sbjct: 67 TQGKLVRVISGAVFDVAVDMRENSLTFGQWVGEVLSAENKHQLWVPEGFAHGFYVLTDEA 126 Query: 130 EVVYKVDNVYAPEYEGGLIWNDPDVNIKWPI-DNPILSEKDKKWPTLKELIE 180 E YK + Y P E LIWND V ++WPI P LS KD L E ++ Sbjct: 127 EFTYKCTDYYNPRAEHSLIWNDQTVGVEWPIYSEPNLSAKDLGGKMLAEAVK 178 >sp|P55468|RFBC_RHISN PROBABLE DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE (DTDP-4-KETO-6-DEOXYGLUCOSE 3,5-EPIMERASE) (DTDP-L-RHAMNOSE SYNTHETASE) >gi|2182415|gb|AAB91686.1| (AE000075) Y4gL [Rhizobium sp. NGR234] Length = 195 Score = 172 bits (431), Expect = 3e-42 Identities = 88/176 (50%), Positives = 116/176 (65%), Gaps = 2/176 (1%) Query: 5 FKRLSIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEFVQDNHSRS-KYGVLRGLH 63 F+ LSI +V LI+P+ F D RG+F E +++ F K VQDN S S + G +RGLH Sbjct: 11 FQSLSIAEVKLIRPRKFGDCRGYFSEVFREKWFRKNVADVGLVQDNESLSAQIGTVRGLH 70 Query: 64 FQKEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFL 123 FQ EP+AQ K+VRC RG +FDVAVD+R SPT+GKWV LS+ N QL++P GFAHGF+ Sbjct: 71 FQLEPFAQGKLVRCTRGALFDVAVDVRVGSPTYGKWVSAELSQENGAQLWVPAGFAHGFM 130 Query: 124 VLSDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWP-IDNPILSEKDKKWPTLKEL 178 L + YKV Y+ E++ GL W+DP + I WP + +LSEKD P+L EL Sbjct: 131 TLKADTVISYKVTAPYSAEHDRGLKWDDPAIGINWPKMTTYVLSEKDSSQPSLCEL 186 >pir||D82828 dTDP-4-dehydrorhamnose 3,5-epimerase XF0257 [imported] - Xylella fastidiosa (strain 9a5c) >gi|9105072|gb|AAF83070.1|AE003879_5 (AE003879) dTDP-4-dehydrorhamnose 3,5-epimerase [Xylella fastidiosa] Length = 185 Score = 169 bits (425), Expect = 1e-41 Identities = 81/170 (47%), Positives = 115/170 (67%), Gaps = 1/170 (0%) Query: 9 SIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEFVQDNHSRSKYGVLRGLHFQKEP 68 ++P ++I+P+VF+D RG F E + F++ G+ FVQ N S S YGVLRGLH+Q P Sbjct: 7 ALPGCLVIEPRVFDDARGEFFEAWNAECFQRQGMSSRFVQSNVSISMYGVLRGLHYQW-P 65 Query: 69 YAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVLSDV 128 Q K+V + G ++DVAVD+R+ SP +G+WV V+LS NK QL+IP GFAHGF+VLS+ Sbjct: 66 RPQGKLVGVLEGEVYDVAVDIRRGSPHYGRWVAVLLSAKNKRQLWIPEGFAHGFVVLSER 125 Query: 129 AEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPIDNPILSEKDKKWPTLKEL 178 A Y +VY E + G+ WND + + WPI P+LS KD+K P ++E+ Sbjct: 126 AVFNYLCTDVYVKEADAGIRWNDALIGVDWPIAVPLLSAKDQKAPFMEEV 175 >gb|AAG09521.1|AF279620_5 (AF279620) dTDP-6-deoxy-D-glucose-3,5-epimerase [Salmonella enterica] Length = 183 Score = 169 bits (425), Expect = 1e-41 Identities = 84/172 (48%), Positives = 111/172 (63%), Gaps = 1/172 (0%) Query: 7 RLSIPDVILIKPKVFEDERGFFMETYKKSDFEKA-GIKGEFVQDNHSRSKYGVLRGLHFQ 65 + I + ++I+P ++ D RGFF E+Y + FE K F QDN S S GVLRGLHFQ Sbjct: 5 KTKIHEALIIEPIIYSDARGFFFESYNQLIFEDLIERKINFCQDNQSLSHKGVLRGLHFQ 64 Query: 66 KEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVL 125 P AQ K+VRC+ G I+DV VDLR +SPT+ KW G +LS NK QL+IP G AHGFL L Sbjct: 65 VNPKAQGKLVRCLHGKIYDVIVDLRVDSPTYKKWEGFVLSASNKKQLWIPEGCAHGFLSL 124 Query: 126 SDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPIDNPILSEKDKKWPTLKE 177 D E+ YK Y+ ++E + WNDP + I+WP+ + I+SEKDK + E Sbjct: 125 EDNTELAYKATEYYSLQHERCIRWNDPSLKIEWPLSDYIISEKDKNGISFSE 176 >pir||T15493 hypothetical protein C14F11.6 - Caenorhabditis elegans >gi|1049348|gb|AAA80364.1| (U39645) similar to DTDP-4-dehydrorhamnose 3,5-epimerase (RFBC gene) [Caenorhabditis elegans] Length = 190 Score = 166 bits (417), Expect = 1e-40 Identities = 90/175 (51%), Positives = 117/175 (66%), Gaps = 8/175 (4%) Query: 9 SIPDVILIKPKVFEDERGFFMETYKKSDF-EKAGIKGEFVQDNHSRSKYGVLRGLHFQKE 67 +IPD+++IKPKVF DERGFF E+Y K+++ EK G + QDNHS S YGVLRGLH Q Sbjct: 19 AIPDLLVIKPKVFPDERGFFSESYNKTEWAEKIGYTEDLQQDNHSFSHYGVLRGLHTQPH 78 Query: 68 PYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVLS- 126 K+V + G IFDVAVD+RK+SPT+GKW GV+L+ NK +IP GF HGF VLS Sbjct: 79 ---MGKLVTVVSGEIFDVAVDIRKDSPTYGKWHGVVLNGDNKHAFWIPAGFLHGFQVLSK 135 Query: 127 DVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPIDNP---ILSEKDKKWPTLKEL 178 + A V YK VY P+ E G+ D D+N+ WPI + I+SE+D + + K L Sbjct: 136 EGAHVTYKCSAVYDPKTEFGINPFDEDINVDWPIRDKTVVIVSERDTQHASFKSL 190 >emb|CAC13136.1| (AJ250139) dTDP-4-dehydrorhamnose 3,5-epimerase [Acetobacter xylinus] Length = 185 Score = 165 bits (413), Expect = 4e-40 Identities = 84/169 (49%), Positives = 111/169 (64%), Gaps = 3/169 (1%) Query: 4 EFKRLSIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEFVQDNHSRSKY-GVLRGL 62 E + ++ +IL+ P F DERG+F ET+ + ++ GI G FVQDNHS S+ GV+RGL Sbjct: 2 EIQTFNVAGIILLTPPRFGDERGYFSETFNAARMKEIGIPGPFVQDNHSLSRARGVVRGL 61 Query: 63 HFQKEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGF 122 H Q P+ Q K+VRC RG I+DV VD+R SPTFG+WVG LSE N QL+IP GF HGF Sbjct: 62 HCQLSPHPQGKLVRCTRGSIWDVGVDIRAGSPTFGQWVGATLSEENGSQLWIPTGFLHGF 121 Query: 123 LVLSDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPI--DNPILSEKD 169 LS+ AEV YK + + + E + W+DP + I WP+ + ILS KD Sbjct: 122 CTLSENAEVQYKCTDYWDRDCERSVRWDDPLLAIDWPVTPKDAILSAKD 170 >pir||S35299 rfbF protein - Yersinia enterocolitica >gi|48590|emb|CAA79352.1| (Z18920) WbbV [Yersinia enterocolitica] Length = 187 Score = 162 bits (406), Expect = 3e-39 Identities = 79/153 (51%), Positives = 111/153 (71%), Gaps = 2/153 (1%) Query: 7 RLSIPDVILIKPKVFEDERGFFMETYKKSDFEKA-GIKGEFVQDNHSRSKYGVLRGLHFQ 65 +LSIP+VIL +P++FED+RG F E++ + F+++ G + FVQ N S SK V+RGLH+Q Sbjct: 5 KLSIPEVILFEPRIFEDDRGHFFESFNLAKFQESIGRQVTFVQSNESYSKQNVIRGLHYQ 64 Query: 66 KEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVL 125 Q K+VR + G +FD+AVDLRK+SPTFG+WVGV+LS+ N QL+IP GF HGF VL Sbjct: 65 VIR-PQGKLVRVVEGEVFDIAVDLRKSSPTFGQWVGVLLSDKNNHQLWIPEGFGHGFQVL 123 Query: 126 SDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKW 158 S A+ Y V + + PE++ + +ND D+NIKW Sbjct: 124 SPSAKFQYMVTDYWYPEHDRCIRFNDSDINIKW 156 >gb|AAG35059.1|AF314183_1 (AF314183) dTDP-rhamnose-3,5-epimerase [Agrobacterium tumefaciens] Length = 189 Score = 162 bits (405), Expect = 3e-39 Identities = 83/167 (49%), Positives = 108/167 (63%), Gaps = 2/167 (1%) Query: 16 IKPKVFEDERGFFMETYKKSDFEKAGIKGEFVQDNHSRS-KYGVLRGLHFQKEPYAQAKI 74 I P F D RG+F E +K+ F + EFVQDN S S + G +RGLHFQ EP+AQ K+ Sbjct: 14 IIPARFGDNRGYFSEVFKREWFRENVANVEFVQDNESLSAQAGTVRGLHFQTEPFAQGKL 73 Query: 75 VRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVLSDVAEVVYK 134 VRCIRG + DVAVD+R SPTFG+W V LS N QL++P GFAHGF+ L + YK Sbjct: 74 VRCIRGRLLDVAVDIRTGSPTFGQWAAVELSPENGEQLWVPAGFAHGFMTLVADTVISYK 133 Query: 135 VDNVYAPEYEGGLIWNDPDVNIKWP-IDNPILSEKDKKWPTLKELIE 180 V Y+ ++ G+ W+DP + I WP + + +LS+KD K P L EL E Sbjct: 134 VTAPYSAAHDRGVKWDDPAIGINWPNVADCVLSDKDAKQPLLSELPE 180 >pir||D49906 rfbD homolog - Xanthomonas campestris pv. campestris >gi|398118|gb|AAA16190.1| (L23941) TDP-rhamnose synthetase [Xanthomonas campestris] Length = 183 Score = 161 bits (402), Expect = 7e-39 Identities = 80/170 (47%), Positives = 108/170 (63%), Gaps = 1/170 (0%) Query: 9 SIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEFVQDNHSRSKYGVLRGLHFQKEP 68 ++P ++I+P VF DERG F ET+ F + G+ FVQ N S S GVLRGLH+Q P Sbjct: 5 TLPGCVVIEPAVFGDERGQFFETWNAERFGQHGLPTSFVQSNVSTSARGVLRGLHYQW-P 63 Query: 69 YAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVLSDV 128 Q K+V + G ++DVAVD+R SP FG+W V+LS N+ Q++IP GFAHGF VLS+ Sbjct: 64 RPQGKLVSVLEGEVYDVAVDIRAGSPHFGRWTAVLLSAENRRQVWIPEGFAHGFAVLSEK 123 Query: 129 AEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPIDNPILSEKDKKWPTLKEL 178 A Y +VY E + G+ W+D + I WP+ +P LS KD K P L E+ Sbjct: 124 ALFSYLCTDVYVKEADAGVRWDDAAIGIDWPVSDPSLSAKDAKAPFLDEV 173 >emb|CAB01950.1| (Z79692) ExpA8 [Sinorhizobium meliloti] Length = 187 Score = 159 bits (399), Expect = 2e-38 Identities = 87/180 (48%), Positives = 110/180 (60%), Gaps = 5/180 (2%) Query: 4 EFKRLSIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEFVQDNHSRSKY-GVLRGL 62 E + L + V+ I P+ DERGFF ETY G+ FVQDNHS S G LRGL Sbjct: 3 EVRSLGLDGVLEIVPRRLGDERGFFSETYNAETLAAHGVAAIFVQDNHSYSAAAGTLRGL 62 Query: 63 HFQKEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKW-QLYIPRGFAHG 121 H+Q P AQAK+VR +RG +FDV VD+RK SPTF KWV + LS KW Q+ +P GFAHG Sbjct: 63 HYQLPPKAQAKLVRVVRGRVFDVVVDIRKGSPTFAKWVALELSA-EKWNQILVPVGFAHG 121 Query: 122 FLVLSDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWP--IDNPILSEKDKKWPTLKELI 179 + L EV+YKV Y+ E+E + ++DP++ I WP D LS KD+ P L E I Sbjct: 122 LVTLDPETEVLYKVSEHYSAEHERSIRYDDPEIGIGWPAATDRLQLSAKDRNAPLLHESI 181 >gb|AAC44073.1| (U51197) dTDP-6-deoxy-D-glucose-3,5-epimerase [Sphingomonas sp. S88] Length = 188 Score = 159 bits (398), Expect = 2e-38 Identities = 81/165 (49%), Positives = 110/165 (66%), Gaps = 5/165 (3%) Query: 9 SIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEFVQDNHSRSKY-GVLRGLHFQKE 67 ++ VI P + D RGFF E +K+S + G++ +VQDN S S G +RGLH Q Sbjct: 8 ALSGVIEFTPPKYGDHRGFFSEVFKQSTLDAEGVEARWVQDNQSFSAAPGTIRGLHLQAP 67 Query: 68 PYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKW-QLYIPRGFAHGFLVLS 126 P+AQAK+VR +RG I+DVAVD+R+ SPT+G+WVGV LS +KW QL +P G+AHGF+ L Sbjct: 68 PFAQAKLVRVLRGAIYDVAVDIRRGSPTYGQWVGVELSA-DKWNQLLVPAGYAHGFMTLV 126 Query: 127 DVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPI--DNPILSEKD 169 E++YKV Y+ E E + W+DPD+ I WP P+LSEKD Sbjct: 127 PDCEILYKVSAKYSKESEMAIRWDDPDLAITWPDIGVEPVLSEKD 171 >pir||F72588 probable dTDP-4-dehydrorhamnose 3,5-epimerase APE1178 - Aeropyrum pernix (strain K1) >gi|5104850|dbj|BAA80164.1| (AP000061) 187aa long hypothetical dTDP-4-dehydrorhamnose 3,5-epimerase [Aeropyrum pernix] Length = 187 Score = 157 bits (394), Expect = 6e-38 Identities = 89/181 (49%), Positives = 114/181 (62%), Gaps = 7/181 (3%) Query: 1 MPFE-FKRLSIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEFVQDNHSRSKYGVL 59 MPF+ FKRL IPD++LIK + F D RGFF E YK++ F GI +F+Q N S S GV+ Sbjct: 1 MPFKVFKRLEIPDIVLIKYERFSDPRGFFAELYKRTPFLAEGIPYDFIQVNLSYSYKGVV 60 Query: 60 RGLHFQKEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFA 119 RGLH+Q +P+ Q K+V + G + DVAVD+RK SP +GK V L L+IP GFA Sbjct: 61 RGLHYQLKPHEQGKLVYVLYGRVLDVAVDIRKGSPWYGKHVSAELKP--GMALWIPPGFA 118 Query: 120 HGFLVLSDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPI---DNPILSEKDKKWPTLK 176 HGF L D A +Y V Y + E + WNDP++ IKWPI D I+S KD+ P LK Sbjct: 119 HGFQALED-ALFLYLVTKEYFKDSERCIKWNDPNLEIKWPIIDDDKVIVSGKDRNCPPLK 177 Query: 177 E 177 E Sbjct: 178 E 178 >pir||S57560 strX protein - Streptomyces glaucescens >gi|2127539|pir||S65586 probable NDP-4-ketohexose 3,5-epimerase StrX - Streptomyces glaucescens >gi|887635|emb|CAA61415.1| (X89010) gtg start codon [Streptomyces glaucescens] >gi|3256045|emb|CAA07373.1| (AJ006985) StrX [Streptomyces glaucescens] Length = 182 Score = 157 bits (392), Expect = 1e-37 Identities = 76/165 (46%), Positives = 105/165 (63%), Gaps = 1/165 (0%) Query: 15 LIKPKVFEDERGFFMETYKKSDFEKAGIKGEFVQDNHS-RSKYGVLRGLHFQKEPYAQAK 73 LI+ DERGFF ++ + +FE+AG++ VQ N S + G LRG H+Q EP A+AK Sbjct: 13 LIELSELRDERGFFSRSFCREEFERAGLEPAVVQCNLSFNHRAGSLRGFHYQTEPNAEAK 72 Query: 74 IVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVLSDVAEVVY 133 +RC RG I+DV VDLR +SPTF + G L+ N+ L++PR FAH +L L+D E VY Sbjct: 73 TIRCTRGAIYDVIVDLRPDSPTFLRHFGAELTADNRLALHVPRNFAHAYLTLADDTETVY 132 Query: 134 KVDNVYAPEYEGGLIWNDPDVNIKWPIDNPILSEKDKKWPTLKEL 178 +V Y P E GL WNDP + ++WP ++S+KD WP L E+ Sbjct: 133 QVSAAYTPGAERGLRWNDPALGVEWPAPVKLVSDKDAGWPLLSEV 177 >gb|AAK41128.1| dTDP-4-dehydrorhamnose 3,5 epimerase (rfbC-1) [Sulfolobus solfataricus] Length = 176 Score = 153 bits (382), Expect = 2e-36 Identities = 89/185 (48%), Positives = 118/185 (63%), Gaps = 10/185 (5%) Query: 1 MPFEFKRLSIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEFVQDNHSRSKYGVLR 60 MPF+F+ L + V+LIKPKVF D+RGFF+E +K +DF K I VQ N S S GV+R Sbjct: 1 MPFDFEDLGM-GVLLIKPKVFPDKRGFFLELFKATDFSKHNIPMP-VQVNMSFSVRGVVR 58 Query: 61 GLHFQKEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAH 120 GLH+Q P Q K+V +G I DVAVD+RK+SPTFGK+ LSE N L+IP GFAH Sbjct: 59 GLHYQITPKEQGKLVFVPKGKILDVAVDVRKSSPTFGKYTSAELSESNHHMLWIPPGFAH 118 Query: 121 GFLVLSDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPIDNPILSEKDKKWPTLKELIE 180 GF L D V + N Y+P++E + ++ I+WPI I+S+KDK+ P L + Sbjct: 119 GFQALDDSLVVYFVTHNDYSPQHERCINYS----YIEWPIKEIIVSDKDKQCPPL----D 170 Query: 181 KDELF 185 K E+F Sbjct: 171 KAEVF 175 >emb|CAB57471.1| (Y18930) dTDP-4-dehydrorhamnose 3,5-epimerase (RfbD) [Sulfolobus solfataricus] Length = 176 Score = 153 bits (382), Expect = 2e-36 Identities = 89/185 (48%), Positives = 118/185 (63%), Gaps = 10/185 (5%) Query: 1 MPFEFKRLSIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEFVQDNHSRSKYGVLR 60 MPF+F+ L + V+LIKPKVF D+RGFF+E +K +DF K I VQ N S S GV+R Sbjct: 1 MPFDFEDLGM-GVLLIKPKVFPDKRGFFLELFKATDFSKHNIPMP-VQVNMSFSVRGVVR 58 Query: 61 GLHFQKEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAH 120 GLH+Q P Q K+V +G I DVAVD+RK+SPTFGK+ LSE N L+IP GFAH Sbjct: 59 GLHYQITPKEQGKLVFVPKGKILDVAVDVRKSSPTFGKYTSAELSESNHHMLWIPPGFAH 118 Query: 121 GFLVLSDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPIDNPILSEKDKKWPTLKELIE 180 GF L D V + N Y+P++E + ++ I+WPI I+S+KDK+ P L + Sbjct: 119 GFQALDDSLVVYFVTHNDYSPQHERCINYS----YIEWPIKEIIVSDKDKQCPPL----D 170 Query: 181 KDELF 185 K E+F Sbjct: 171 KAEVF 175 >gb|AAK42118.1| dTDP-4-dehydrorhamnose 3,5 epimerase (rfbC-2) [Sulfolobus solfataricus] Length = 176 Score = 150 bits (374), Expect = 1e-35 Identities = 85/177 (48%), Positives = 113/177 (63%), Gaps = 6/177 (3%) Query: 1 MPFEFKRLSIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEFVQDNHSRSKYGVLR 60 MPFEF+ L + ++LIKPKVF D+RGFF+E +K DF KA I VQ N S S GV+R Sbjct: 1 MPFEFENLGM-GIVLIKPKVFPDKRGFFLEVFKSEDFTKAEIPN-IVQTNMSFSFKGVVR 58 Query: 61 GLHFQKEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAH 120 GLH+Q P Q K+V +G I DVA+DLRK+SPTFGK+V V L++ N + L+IP GFAH Sbjct: 59 GLHYQITPKEQGKLVFVPKGKILDVALDLRKSSPTFGKYVKVELNDENHYILWIPPGFAH 118 Query: 121 GFLVLSDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPIDNPILSEKDKKWPTLKE 177 GF L D V + N Y+ E + ++ D WPI I+S+KD + P L++ Sbjct: 119 GFQALEDSIVVYFLTHNEYSKSDERCVNYSYVD----WPIKEFIISDKDSQCPPLEK 171 >emb|CAB65208.1| (AJ007311) RmlC protein [Legionella pneumophila] Length = 188 Score = 141 bits (351), Expect = 7e-33 Identities = 74/162 (45%), Positives = 103/162 (62%), Gaps = 2/162 (1%) Query: 10 IPDVILIKPKVFEDERGFFMETYKKSDFEKA-GIKGEFVQDNHSRSKYGVLRGLHFQKEP 68 I ++ +I+PK++ DERGFF E+++ +E+ GI FVQDN S+ + + K Sbjct: 8 IDELKIIEPKIYGDERGFFYESFQAKRYEELLGITDRFVQDNFSKITKRCTKEVCIIKVN 67 Query: 69 YAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVLSDV 128 Q K+V + G +FDVAVD+R SPTFG+WVGVILS NK Q +IP+GFAHGF VLS + Sbjct: 68 KTQGKLVSVLAGEVFDVAVDIRLGSPTFGQWVGVILSGENKRQFWIPKGFAHGFYVLSAM 127 Query: 129 AEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPIDNPI-LSEKD 169 A+ YK + Y PE E + + DP + I WP+ + LS KD Sbjct: 128 ADFAYKCTDYYHPESEFSIHYLDPQLAIDWPLGEQVQLSPKD 169 >gb|AAA88702.1| (L33181) CDP-3, 6-dideoxy-D-glycero-D-glycero-4-hexulose-5-epimerase [Yersinia pseudotuberculosis] >gi|7242220|gb|AAB31758.2| (S72887) 22 kda protein [Yersinia pseudotuberculosis] Length = 187 Score = 137 bits (341), Expect = 1e-31 Identities = 68/165 (41%), Positives = 101/165 (61%), Gaps = 2/165 (1%) Query: 5 FKRLSIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEFVQDNHSRSKYGVLRGLHF 64 FK+L I LI+ F D RG F++T+ F + GI + ++ +S S V+RG+HF Sbjct: 12 FKKLDIEGCYLIEFNKFIDSRGTFVKTFHSDFFSENGIVLDMREEFYSISAKNVIRGMHF 71 Query: 65 QKEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLV 124 Q P K+V C+ G + DV +D+RK+S T+G++ + LS N L++P+G AHGFL Sbjct: 72 QMPPAEHDKLVYCVNGAVLDVILDIRKDSKTYGEYFSIELSYENSLALWVPKGLAHGFLS 131 Query: 125 LSDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPIDNPILSEKD 169 L+D + + YK +V+ E + G+ WN KWPIDNPI+SEKD Sbjct: 132 LADNSIMFYKTSSVHNVECDSGIKWN--SFGFKWPIDNPIISEKD 174 >gb|AAC60763.1| (U46859) WbcA [Yersinia enterocolitica (type 0:8)] Length = 174 Score = 132 bits (330), Expect = 2e-30 Identities = 62/170 (36%), Positives = 104/170 (60%), Gaps = 2/170 (1%) Query: 1 MPFEFKRLSIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEFVQDNHSRSKYGVLR 60 M L+I LI+ +F DERG F++T+ + F+ G++ ++ +SRSK V+R Sbjct: 1 MIINITELNISGCYLIESPIFSDERGEFVKTHHQEIFKNFGLEIPSAEEYYSRSKNNVIR 60 Query: 61 GLHFQKEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAH 120 G+HFQ+ P K+V C G + DV +D+RK+S T+G+++ I + N+ +++ +G AH Sbjct: 61 GMHFQQYPDDHNKLVFCPEGEVLDVFLDIRKDSNTYGQFMSFISNPHNRRSIFLAKGIAH 120 Query: 121 GFLVLSDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPIDNPILSEKDK 170 GFL + D +V K V++P + G+ WN KWP++NPI+S+KD+ Sbjct: 121 GFLSMKDNTLIVCKTSTVHSPSRDSGIHWN--SFGFKWPVENPIISDKDR 168 >gb|AAG29805.1| (AF235050) dTDP-4-keto-6-deoxyglucose 3,5-epimerase [Streptomyces rishiriensis] Length = 198 Score = 129 bits (320), Expect = 3e-29 Identities = 66/168 (39%), Positives = 93/168 (55%), Gaps = 1/168 (0%) Query: 4 EFKRLSIPDVILIKPKVFEDERGFFMETYKKSDFE-KAGIKGEFVQDNHSRSKYGVLRGL 62 + + L I I PK D RG F++ Y+ F + G Q N S S GV+RG+ Sbjct: 2 KLRPLGIEGAWEITPKQHADPRGVFLDWYRVDQFAAEVGRPLRLAQANLSVSVRGVVRGV 61 Query: 63 HFQKEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGF 122 HF P QAK V C+RG +FDV VDLR SPT+G+W G L + ++ +Y+ G HGF Sbjct: 62 HFADVPPGQAKYVTCVRGALFDVVVDLRVGSPTYGRWEGTRLDDVSRRAVYLSEGIGHGF 121 Query: 123 LVLSDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPIDNPILSEKDK 170 +SD A + Y Y P E G+ DP++ I WP++ P+LS +D+ Sbjct: 122 CAISDEATLCYLSSQTYNPASEHGVHPLDPELAINWPVETPLLSARDQ 169 >gb|AAF59933.1| (AF237895) dTDP-4-keto-6-deoxyglucose 3,5-epimerase [Streptomyces antibioticus] Length = 202 Score = 127 bits (316), Expect = 9e-29 Identities = 71/175 (40%), Positives = 93/175 (52%), Gaps = 2/175 (1%) Query: 8 LSIPDVILIKPKVFEDERGFFMETYKKSDF-EKAGIKGEFVQDNHSRSKYGVLRGLHFQK 66 L + L P++ DERG F+E ++ F EK G Q N S S+ GVLRG+HF Sbjct: 4 LDVDGAWLYTPEIMRDERGEFLEWFRGRTFQEKIGHPLSLAQANCSVSRKGVLRGIHFAD 63 Query: 67 EPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVLS 126 P QAK V C G + DV VD+R+ SPTFG+W V L LY+ G H F+ L+ Sbjct: 64 APPGQAKYVTCASGTVLDVVVDVRRGSPTFGRWAAVRLDAARHQGLYLAEGLGHAFMALT 123 Query: 127 DVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPID-NPILSEKDKKWPTLKELIE 180 D A VVY Y E E + DP + I+WP D + +LS KD P+L + E Sbjct: 124 DDATVVYLCSQPYVAEAERAVDPLDPAIGIEWPTDIDIVLSAKDTHAPSLAQAAE 178 >pir||S74752 dTDP-6-deoxy-L-mannose-dehydrogenase - Synechocystis sp. (strain PCC 6803) >gi|1651977|dbj|BAA16903.1| (D90901) dTDP-6-deoxy-L-mannose-dehydrogenase [Synechocystis sp.] Length = 189 Score = 127 bits (315), Expect = 1e-28 Identities = 67/154 (43%), Positives = 89/154 (57%), Gaps = 1/154 (0%) Query: 23 DERGFFMETYKKSDFEKAGIKGEFVQDNHSRSKYG-VLRGLHFQKEPYAQAKIVRCIRGV 81 D RGF + + ++ G Q NH+ + G +RG+H+Q P A+ K+V CIRG Sbjct: 27 DRRGFLARLFCAEELKEVGWHKPIAQINHTHTAQGGTVRGMHYQNPPSAEMKLVTCIRGQ 86 Query: 82 IFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVLSDVAEVVYKVDNVYAP 141 ++DVAVDLR +SPTF W GV+LS N L IP G AHGF LSD E++Y Y P Sbjct: 87 VWDVAVDLRVDSPTFLTWQGVVLSADNNRALLIPEGCAHGFQALSDDVELIYCHSVAYNP 146 Query: 142 EYEGGLIWNDPDVNIKWPIDNPILSEKDKKWPTL 175 EGGL DP + I+WP LS++D+ P L Sbjct: 147 MAEGGLNPQDPRLGIEWPQAITELSQRDQNHPLL 180 >pir||F70566 probable dtdp-4-dehydrorhamnose 3 - Mycobacterium tuberculosis (strain H37RV) >gi|2104388|emb|CAB08731.1| (Z95390) rmlC [Mycobacterium tuberculosis] Length = 202 Score = 127 bits (315), Expect = 1e-28 Identities = 68/177 (38%), Positives = 99/177 (55%), Gaps = 4/177 (2%) Query: 6 KRLSIPDVILIKPKVFEDERGFFMETYKKSDFEK-AGIKGEFVQDNHSRSKYGVLRGLHF 64 + L +P I P + D RG F E F AG + Q N S S GVLRGLHF Sbjct: 4 RELDVPGAWEITPTIHVDSRGLFFEWLTDHGFRAFAGHSLDVRQVNCSVSSAGVLRGLHF 63 Query: 65 QKEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLV 124 + P +QAK V C+ G +FDV VD+R+ SPTFG+W V+L + ++ +Y+ G AHGFL Sbjct: 64 AQLPPSQAKYVTCVSGSVFDVVVDIREGSPTFGRWDSVLLDDQDRRTIYVSEGLAHGFLA 123 Query: 125 LSDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPIDN---PILSEKDKKWPTLKEL 178 L D + V+Y Y P+ E + DP + + WP+ + P LS++D P+ +++ Sbjct: 124 LQDNSTVMYLCSAEYNPQREHTICATDPTLAVDWPLVDGAAPSLSDRDAAAPSFEDV 180 >emb|CAB39840.1| (AL049491) putative dTDP-4-dehydrorhamnose 3,5-epimerase [Mycobacterium leprae] Length = 202 Score = 127 bits (315), Expect = 1e-28 Identities = 71/177 (40%), Positives = 95/177 (53%), Gaps = 4/177 (2%) Query: 6 KRLSIPDVILIKPKVFEDERGFFMETYKKSDFEK-AGIKGEFVQDNHSRSKYGVLRGLHF 64 K L I I P + D RG F E S F G + + Q N S S GVLRGLHF Sbjct: 4 KELDISGAWEITPTIHSDSRGMFFEWLTASRFSAFTGHRLDVRQANCSVSSAGVLRGLHF 63 Query: 65 QKEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLV 124 + P +QAK V C+ G +FDV VD+R SPTFG W + L++ N+ +YI AHGFL Sbjct: 64 AQVPPSQAKYVTCVTGSVFDVVVDIRLGSPTFGCWTSITLNDSNRKTIYISESLAHGFLA 123 Query: 125 LSDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPIDNPI---LSEKDKKWPTLKEL 178 L D + V+Y Y P E + DPD+ I WP+ + + LS++D P L ++ Sbjct: 124 LQDNSTVMYLCSAEYNPAREHAICATDPDLAIDWPVVDGVDTHLSKRDATAPNLDDI 180 >dbj|BAA84596.1| (AB032523) dTDP-4-keto-6-deoxyhexose 3,5-epimerase [Streptomyces avermitilis] Length = 225 Score = 123 bits (307), Expect = 1e-27 Identities = 70/185 (37%), Positives = 102/185 (54%), Gaps = 8/185 (4%) Query: 6 KRLSIPDVILIKPKVFEDERGFFMETYKKSDFEKA-GIKGEFVQDNHSRSKYGVLRGLHF 64 +RL + + P VF DERG F+ Y++ +A G + Q S S+ GV+RG+HF Sbjct: 30 RRLVVEGAVEFTPTVFPDERGLFVTPYQEPVLSEAVGHRFPTAQTCQSVSRRGVVRGVHF 89 Query: 65 QKEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLV 124 P QAK V C RG D VDLR SPTFG+W V+L + +Y+P G H F+ Sbjct: 90 TATPPGQAKYVHCARGRALDFVVDLRTGSPTFGQWDSVLLDQERFRSVYLPIGVGHAFVA 149 Query: 125 LSDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPIDN-----PILSEKDKKWPTLKELI 179 L D +VY + + Y P+ E L DPD+ + P+ + PILSE+D++ PTL++ + Sbjct: 150 LEDDTAMVYLMSSGYVPQNEHALSPEDPDLAL--PLGHHLGRAPILSERDRRAPTLQQAL 207 Query: 180 EKDEL 184 + L Sbjct: 208 RRGML 212 >gb|AAF67516.1|AF170880_23 (AF170880) NovW [Streptomyces spheroides] Length = 207 Score = 122 bits (304), Expect = 2e-27 Identities = 67/164 (40%), Positives = 89/164 (53%), Gaps = 1/164 (0%) Query: 8 LSIPDVILIKPKVFEDERGFFMETYKKSDFEKA-GIKGEFVQDNHSRSKYGVLRGLHFQK 66 L I V I P+ D RG F++ Y F +A G Q N S S GV+RG+HF Sbjct: 6 LGIEGVWEITPEQRADPRGVFLDWYHVDRFAEAIGRPLRLAQANLSVSVRGVVRGIHFVD 65 Query: 67 EPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVLS 126 P QAK V C+RG +FDV VDLR SPT+G W G L + ++ +Y+ G HGF +S Sbjct: 66 VPPGQAKYVTCVRGAVFDVVVDLRVGSPTYGCWEGTRLDDVSRRAVYLSEGIGHGFCAIS 125 Query: 127 DVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPIDNPILSEKDK 170 D A + Y Y P E G+ DP++ I WP P+LS +D+ Sbjct: 126 DEATLCYLSSGTYDPATEHGVHPLDPELAIDWPTGTPLLSPRDQ 169 >pir||JE0089 dTDP-4-dehydrorhamnose 3,5-epimerase (EC 5.1.3.13) - Azotobacter vinelandii Length = 186 Score = 122 bits (303), Expect = 3e-27 Identities = 68/179 (37%), Positives = 98/179 (53%), Gaps = 1/179 (0%) Query: 3 FEFKRLSIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEFVQDNHSRSKY-GVLRG 61 F L + + L++ + F D RGF + + G Q NH+ + + G +RG Sbjct: 4 FTVTDLPLAGLKLVERRRFGDSRGFLARLFCAEELAATGWLQPIAQINHTFTTWRGTVRG 63 Query: 62 LHFQKEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHG 121 +HFQ+ P+A+AK+V C++G ++DVAVDLR SPTF W LS N L IP GFAHG Sbjct: 64 MHFQRPPHAEAKLVTCLQGEVWDVAVDLRAGSPTFLHWHAERLSADNARALLIPEGFAHG 123 Query: 122 FLVLSDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPIDNPILSEKDKKWPTLKELIE 180 F L++ A ++Y YAP EGGL D + I WP++ LS +D P ++ E Sbjct: 124 FQTLTNGAALLYCHSAAYAPGAEGGLHPQDERLGIAWPLEIRELSVRDAMHPMVEGAFE 182 >sp|P29783|STRM_STRGR DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE (DTDP-4-KETO-6-DEOXYGLUCOSE 3,5-EPIMERASE) (DTDP-L-RHAMNOSE SYNTHETASE) >gi|68398|pir||XUSMEG dTDP-4-dehydrorhamnose 3,5-epimerase (EC 5.1.3.13) - Streptomyces griseus >gi|581676|emb|CAA44442.1| (X62567) dTDP-4-dehydrorhamnose 3,5-epimerase [Streptomyces griseus] Length = 200 Score = 122 bits (302), Expect = 4e-27 Identities = 70/173 (40%), Positives = 95/173 (54%), Gaps = 3/173 (1%) Query: 8 LSIPDVILIKPKVFEDERGFFMETYKKSDFEKA-GIKGEFVQDNHSRSKYGVLRGLHFQK 66 LS+ L + + F D+RG F E Y A G Q N S S+ GVLRG+HF + Sbjct: 4 LSVQGAWLSETRAFADDRGEFQELYSARSLRGALGYDPGVAQVNRSVSRRGVLRGVHFAQ 63 Query: 67 EPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVLS 126 P +QAK V C+ G + DV VD+R SPT+ W V L + ++ LY+ G H F+ L+ Sbjct: 64 LPPSQAKYVTCLSGAVLDVVVDIRTGSPTYRAWEAVRLDDPHR-SLYVEAGLGHSFMALT 122 Query: 127 DVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPID-NPILSEKDKKWPTLKEL 178 D A VVY YA E G+ DPD+ I WP P+LSEKD++ P + E+ Sbjct: 123 DDAVVVYLTSQGYAAGREHGVHPLDPDLGIAWPDGIEPVLSEKDRQAPGIAEM 175 >pir||S44236 dTDP-4-keto-6-deoxyglucose 3,5-epimerase - Streptomyces glaucescens >gi|581679|emb|CAA55578.1| (X78975) dTDP-4-keto-6-deoxyglucose 3,5-epimerase [Streptomyces glaucescens] >gi|3256061|emb|CAA07389.1| (AJ006985) StrM [Streptomyces glaucescens] Length = 200 Score = 121 bits (300), Expect = 7e-27 Identities = 70/172 (40%), Positives = 93/172 (53%), Gaps = 3/172 (1%) Query: 8 LSIPDVILIKPKVFEDERGFFMETYKKSDF-EKAGIKGEFVQDNHSRSKYGVLRGLHFQK 66 L I L++ +VF DERG F E ++ + G Q N S S+ GV+RG+HF Sbjct: 4 LGIEGAWLVESRVFGDERGEFQELFRGGPLSDTLGYVPGVAQVNRSVSRKGVVRGVHFAD 63 Query: 67 EPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVLS 126 P QAK V C+RG + DV VD+R SP +G W V L + + +YI G H F+ L+ Sbjct: 64 VPPGQAKYVTCLRGAVLDVVVDIRAGSPAYGAWETVRLDDPRR-SVYIEAGLGHAFMALT 122 Query: 127 DVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPID-NPILSEKDKKWPTLKE 177 D A VVY YAPE E + DP + I WP P+LS KD + P L+E Sbjct: 123 DDATVVYLTSEGYAPEREHAVHPLDPALGIAWPPGIEPVLSAKDSRAPGLEE 174 >emb|CAB58341.1| (AL121855) putative epimerase [Streptomyces coelicolor A3(2)] Length = 183 Score = 120 bits (299), Expect = 9e-27 Identities = 68/182 (37%), Positives = 102/182 (55%), Gaps = 5/182 (2%) Query: 6 KRLSIPDV---ILIKPKVFEDERGFFMETYKKSDFEKAGIK-GEFVQDNHSRSKYGVLRG 61 K +P++ L +P D RGFF T+ G+ FVQD+ SRS GVLRG Sbjct: 2 KATEVPEISGAYLFRPTPHADARGFFCRTFDADVVRSVGLDPAAFVQDSVSRSVRGVLRG 61 Query: 62 LHFQKEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHG 121 LH + +AK+VRC G IFD VDLR +SPT+ LS + LYIP G AHG Sbjct: 62 LHLRSGA-GEAKLVRCSNGRIFDAVVDLRADSPTYLGRAFFELSGETQTTLYIPAGCAHG 120 Query: 122 FLVLSDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPIDNPILSEKDKKWPTLKELIEK 181 F L++ ++V Y++D + P + + ++DPD+ I WP+ +S +D++ P+L + ++ Sbjct: 121 FQSLTETSDVSYRIDRAHDPAEDVTIAFDDPDLAIDWPLPVASVSPRDREAPSLADFLKH 180 Query: 182 DE 183 E Sbjct: 181 RE 182 >pir||T46670 probable 3,5-epimerase nogF [imported] - Streptomyces nogalater >gi|2916806|emb|CAA12011.1| (AJ224512) SnogF [Streptomyces nogalater] Length = 201 Score = 118 bits (292), Expect = 6e-26 Identities = 69/178 (38%), Positives = 95/178 (52%), Gaps = 3/178 (1%) Query: 4 EFKRLSIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEF--VQDNHSRSKYGVLRG 61 E + L + P+VF D RG F+ ++++ +A F Q NHSRS+ GV+RG Sbjct: 2 ESRTLLVEGAHAFTPRVFPDARGCFVSPFQQTPVAEALGHRLFPVAQTNHSRSRRGVVRG 61 Query: 62 LHFQKEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHG 121 HF P AK V C RG D +D+R SPTFG+W V+L + N +Y P G AH Sbjct: 62 AHFTLTPPGIAKYVYCARGRARDYVIDIRVGSPTFGQWDSVVLDDRNFRAMYFPVGVAHA 121 Query: 122 FLVLSDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPIDNP-ILSEKDKKWPTLKEL 178 F L D + Y + Y + E L DPD+ ++ P D P +LSE+D PTL+EL Sbjct: 122 FAALEDDTVMSYMLSGEYVADNELALSVFDPDLALELPGDTPLLLSERDTAAPTLREL 179 >gb|AAD41820.1|AF147703_6 (AF147703) putative NDP-hexose 3-epimerase TylJ [Streptomyces fradiae] Length = 205 Score = 118 bits (292), Expect = 6e-26 Identities = 64/172 (37%), Positives = 96/172 (55%), Gaps = 2/172 (1%) Query: 8 LSIPDVILIKPKVFEDERGFFMETYKKSDFEK-AGIKGEFVQDNHSRSKYGVLRGLHFQK 66 L I +I+P++ D RG F ++ S+F + G Q N + S+ G LRG+HF + Sbjct: 8 LGIEGAWVIQPEIHPDRRGEFHAWFQSSEFRRLTGHSFSVPQVNIAVSRKGALRGIHFSE 67 Query: 67 EPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVLS 126 P QAK C++G +V VD+R SPT+G+W V + E+N+ +Y+P G F+ L+ Sbjct: 68 VPPGQAKYSACVQGAGVEVVVDIRLGSPTYGQWRAVPVDEYNRTAVYVPAGLGRAFVALT 127 Query: 127 DVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPID-NPILSEKDKKWPTLKE 177 D +VY + YA E + DPD+ I WP D +LSE+D + PTL E Sbjct: 128 DRTTLVYLCSSEYAARREHAVNPLDPDLAIAWPEDVELLLSERDTRAPTLAE 179 >gb|AAB66649.1| (U43540) rmlC gene product [Mycobacterium tuberculosis] Length = 203 Score = 113 bits (281), Expect = 1e-24 Identities = 69/182 (37%), Positives = 100/182 (54%), Gaps = 5/182 (2%) Query: 4 EFKRLSIPDVILIKPKVFEDERGFFMETYKKSDFEK-AGIKGEFVQDNHSRSKYGVLRGL 62 E + L +P I P + D RG F E F AG + Q N S S GVLRGL Sbjct: 4 EPRELDVPGAWEITPTIHVDSRGLFFEWLTDHGFRAFAGHSLDVRQVNCSVSSAGVLRGL 63 Query: 63 HFQKEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGF 122 HF + P +QAK V C+ G +FDV VD+R+ SPTFG+W V+L + ++ +Y+ G AHGF Sbjct: 64 HFAQLPPSQAKYVTCVSGSVFDVVVDIREGSPTFGRWDSVLLDDQDR-NIYVSDGLAHGF 122 Query: 123 LVLSDVAEVVYKVDNVYAPEYEGGLIWNDPDV-NIKWPIDN--PILSEKDKKWPTLKELI 179 L L D + V+Y Y P+ + + DP + +I+ D P LS++D P+ +E + Sbjct: 123 LALQDNSTVMYLCSAEYNPQRQHTICATDPTLASIRRWSDGGCPSLSDRDAAAPSFEEDV 182 Query: 180 EK 181 + Sbjct: 183 RR 184 >gb|AAD12169.1| (AF055922) epimerase [Streptomyces fradiae] Length = 205 Score = 113 bits (281), Expect = 1e-24 Identities = 62/172 (36%), Positives = 94/172 (54%), Gaps = 2/172 (1%) Query: 8 LSIPDVILIKPKVFEDERGFFMETYKKSDFEK-AGIKGEFVQDNHSRSKYGVLRGLHFQK 66 L I +I+P++ D RG F ++ S+F + G Q N + S+ G G+HF + Sbjct: 8 LGIEGAWVIQPEIHPDRRGEFHAWFQSSEFRRLTGHSFSVPQVNIAVSRKGAAAGIHFSE 67 Query: 67 EPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVLS 126 P QAK C++G +V VD+R SPT+G+W V + E+N+ +Y+P G F+ L+ Sbjct: 68 VPPGQAKYSACVQGAGVEVVVDIRLGSPTYGQWRAVPVDEYNRTAVYVPAGLGRAFVALT 127 Query: 127 DVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPID-NPILSEKDKKWPTLKE 177 D +VY + YA E + DPD+ I WP D +LSE+D + PTL E Sbjct: 128 DRTTLVYLCSSEYAARREHAVNPLDPDLAIAWPEDVELLLSERDTRAPTLAE 179 >gb|AAF70101.1|AF257324_2 (AF257324) AknL [Streptomyces galilaeus] Length = 201 Score = 111 bits (274), Expect = 8e-24 Identities = 61/178 (34%), Positives = 92/178 (51%), Gaps = 3/178 (1%) Query: 4 EFKRLSIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEF--VQDNHSRSKYGVLRG 61 +F+ L++ + P VFED+RG F +++ F A F Q NHSRS+ G +RG Sbjct: 2 QFRELAVSGAFVFTPPVFEDDRGLFTSPFQEPAFVAALGHPLFPVAQSNHSRSRRGTVRG 61 Query: 62 LHFQKEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHG 121 +H+ P AK V C RG D+ VD+R SPT+G+W +L +Y P G H Sbjct: 62 IHYTVTPPGVAKYVYCARGRAIDIVVDIRVGSPTYGRWDSSVLDPEGFRAMYFPVGVGHA 121 Query: 122 FLVLSDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPID-NPILSEKDKKWPTLKEL 178 F+ L D + Y + Y ++E L DP + + P D P+LS +D P L+++ Sbjct: 122 FVALEDDTVMSYMLSGSYEAQHEMSLSPLDPALGLPIPQDVAPLLSARDTAAPLLEQV 179 >gb|AAB84077.1| (U77459) EryBVII [Saccharopolyspora erythraea] >gi|2665341|emb|CAA72086.1| (Y11199) putative TDP-4-keto-6-deoxyglucose 3,5 epimerase or 5-epimerase [Saccharopolyspora erythraea] Length = 193 Score = 109 bits (269), Expect = 3e-23 Identities = 64/154 (41%), Positives = 79/154 (50%), Gaps = 2/154 (1%) Query: 18 PKVFEDERGFFMETYKKSDFEKA-GIKGEFVQDNHSRSKYGVLRGLHFQKEPYAQAKIVR 76 P +D RG F+ + F A G + Q NH S GVLRGLHF P Q K V Sbjct: 9 PDPKQDRRGLFVSPLQDEAFVGAVGHRFPVAQMNHIVSARGVLRGLHFTTTPPGQCKYVY 68 Query: 77 CIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVLSDVAEVVYKVD 136 C RG DV VD+R SPTFGKW V + + +Y PRG AH FL L D + Y V Sbjct: 69 CARGRALDVIVDIRVGSPTFGKWDAVEMDTEHFRAVYFPRGTAHAFLALEDDTLMSYLVS 128 Query: 137 NVYAPEYEGGLIWNDPDVNIKWPID-NPILSEKD 169 Y EYE + DP + + WP D +LS++D Sbjct: 129 TPYVAEYEQAIDPFDPALGLPWPADLEVVLSDRD 162 >pir||T30591 conserved hypothetical protein PCZA361.16 - Amycolatopsis orientalis >gi|2894174|emb|CAA11781.1| (AJ223998) PCZA361.16 [Amycolatopsis orientalis] Length = 205 Score = 108 bits (268), Expect = 4e-23 Identities = 62/177 (35%), Positives = 95/177 (53%), Gaps = 7/177 (3%) Query: 6 KRLSIPDVILIKPKVFEDERGFFMETYKKSDFEKA--GIKGEFVQDNHSRSKYGVLRGLH 63 ++L++ I P+VF D+RG + Y++ F +A G Q HS SK GV+RG+H Sbjct: 4 RKLAVDGAIEFTPRVFADDRGLLILPYQEEAFVEAHGGPLFRVAQTIHSMSKRGVVRGIH 63 Query: 64 FQKEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFL 123 + P AK V C RG D+ +D+R SPTFG+W V++ + + +Y+P G H F+ Sbjct: 64 YTVTPPGTAKYVYCARGKAMDIVIDIRVGSPTFGQWDSVLMDQQDPRAVYLPVGVGHAFV 123 Query: 124 VLSDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPID---NPILSEKDKKWPTLKE 177 L D + Y + Y + E L DP + + PID PI+S++D+ TL E Sbjct: 124 ALEDDTVMSYMLSRSYVTQDELALSALDPALGL--PIDIGVEPIVSDRDRVAITLAE 178 >gb|AAG13911.1|AF263245_7 (AF263245) TDP-4-keto-6-deoxyhexose 3,5-epimerase [Micromonospora megalomicea subsp. nigra] Length = 201 Score = 108 bits (266), Expect = 7e-23 Identities = 67/175 (38%), Positives = 96/175 (54%), Gaps = 3/175 (1%) Query: 6 KRLSIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEF--VQDNHSRSKYGVLRGLH 63 + L I V P+ F DERG F Y++ F A + F Q + +RS+ GV+RG+H Sbjct: 4 EELGIEGVFTFTPQTFADERGVFGTAYQEDVFVAALGRPLFPVAQVSTTRSRRGVVRGVH 63 Query: 64 FQKEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFL 123 F P + AK V C RG D AVD+R SPTFG+ V LS + LY+P G H F+ Sbjct: 64 FTTMPGSMAKYVYCARGRAMDFAVDIRPGSPTFGRAEPVELSAESMVGLYLPVGMGHLFV 123 Query: 124 VLSDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPID-NPILSEKDKKWPTLKE 177 L D +VY + Y P+ E + DP++ + P D + ++SE+D+ PTL+E Sbjct: 124 SLEDDTTLVYLMSAGYVPDKERAVHPLDPELALPIPADLDLVMSERDRVAPTLRE 178 >gb|AAC01732.1| (AF040570) dNTP-hexose 3,5 epimerase [Amycolatopsis mediterranei] Length = 206 Score = 107 bits (264), Expect = 1e-22 Identities = 61/172 (35%), Positives = 93/172 (53%), Gaps = 2/172 (1%) Query: 8 LSIPDVILIKPKVFEDERGFFMETYKKSDFEKA-GIKGEFVQDNHSRSKYGVLRGLHFQK 66 L+I ++ + F DERG F E Y++ +A G + F+Q N S S V+RG+H Sbjct: 6 LAIDGAHVVTSQSFGDERGDFFEVYRQDVLTEALGYRPRFLQTNVSTSCRNVVRGVHGAM 65 Query: 67 EPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVLS 126 P AK V C+RG + D VD+R SPTFG+W ++L++ +Y+ G H F+ L Sbjct: 66 TPPGLAKFVTCLRGSLLDFVVDVRTGSPTFGQWDMIVLNQHGGTAVYVEEGLGHAFVSLE 125 Query: 127 DVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPI-DNPILSEKDKKWPTLKE 177 D V Y + ++Y P + DP++ + + PILSE+D PTL+E Sbjct: 126 DDTCVQYLLSDLYRPAEVLTVQPLDPEIGLPLNLPGEPILSERDAAAPTLRE 177 >pir||T46530 probable dTDP-4-keto-6-deoxyglucose-2,3-dehydratase [imported] - Streptomyces violaceoruber >gi|4218557|emb|CAA09646.1| (AJ011500) putative dTDP-4-keto-6-deoxyglucose-2,3-dehydratase [Streptomyces violaceoruber] Length = 195 Score = 107 bits (264), Expect = 1e-22 Identities = 61/174 (35%), Positives = 93/174 (53%), Gaps = 2/174 (1%) Query: 10 IPDVILIKPKVFEDERGFFMETYKKSDFEKA-GIKGEFVQDNHSRSKYGVLRGLHFQKEP 68 +P +I P+ + D RG F E+ + +A G E Q N+S S+ LRG+H P Sbjct: 9 VPGAYVITPRQWPDPRGTFFESLRTDLVSEAVGRPFEVRQINYSTSRRNTLRGVHGVLIP 68 Query: 69 YAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVLSDV 128 QAK V C+RG + D+ VDLR SPTFG+ +L+ N +++ G HGFL L+D Sbjct: 69 PGQAKYVTCVRGALRDMVVDLRVGSPTFGQSASTLLTPENGVAVHVAEGLGHGFLALTDD 128 Query: 129 AEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPIDN-PILSEKDKKWPTLKELIEK 181 + Y + + P + + DPD+ + W D P+LS KD P+L+ +E+ Sbjct: 129 TCISYALSTAHVPGTQFEIDPLDPDLALPWGFDEPPLLSAKDAGAPSLRTALER 182 >gb|AAB63046.1| (AF006633) putative epimerase [Streptomyces peucetius] Length = 208 Score = 106 bits (262), Expect = 2e-22 Identities = 61/175 (34%), Positives = 90/175 (50%), Gaps = 3/175 (1%) Query: 6 KRLSIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEFV--QDNHSRSKYGVLRGLH 63 + L++ +P+VF DERG F+ +++ F A F Q NHSRS+ GV+RG+H Sbjct: 4 RELAVQGAYTFEPEVFPDERGLFVSPFREDAFTAAVGHPLFPVRQTNHSRSRRGVVRGVH 63 Query: 64 FQKEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFL 123 + P AK V C RG D+ VD+R SPT+G+W V L +Y P G H F+ Sbjct: 64 YTVTPPGSAKYVYCARGRSLDIVVDVRVGSPTYGRWDAVELEPREFRAVYFPVGVGHAFV 123 Query: 124 VLSDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPID-NPILSEKDKKWPTLKE 177 L D + Y + Y E + DP + + P D P+LS +D+ P L++ Sbjct: 124 ALEDDTVMSYMLSGEYVQANELAVSVLDPALGLPVPGDLEPLLSGRDRAAPPLEQ 178 >pir||S39966 hypothetical protein - Streptomyces griseus >gi|407886|emb|CAA51671.1| (X73148) ORF4 [Streptomyces griseus] >gi|742317|prf||2009361D ORF 4 in daunorubicin synthesis gene [Streptomyces griseus] Length = 212 Score = 104 bits (258), Expect = 6e-22 Identities = 59/173 (34%), Positives = 88/173 (50%), Gaps = 3/173 (1%) Query: 6 KRLSIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEFV--QDNHSRSKYGVLRGLH 63 + L++ P+V+ D+RG F+ +++ F K F Q NHS S GV+RG+H Sbjct: 4 RELAVEGAYTFVPEVYPDDRGLFVSPFREQGFTKVVGHPLFPVRQTNHSLSGRGVVRGVH 63 Query: 64 FQKEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFL 123 + P AK V C RG D+ VD+R SPT+G+W V L +Y P G H F+ Sbjct: 64 YTVTPPGTAKYVYCARGRSLDIIVDVRVGSPTYGRWDAVELDPGEFRAVYFPVGVGHAFV 123 Query: 124 VLSDVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPID-NPILSEKDKKWPTL 175 L + + Y + Y P +E + DP + + P D P+LSE+D+ P L Sbjct: 124 ALEEDTVMSYMLSGEYVPSHELAVSALDPALGLPVPADTEPLLSERDRVAPDL 176 >gb|AAD13558.1| (AF080235) NDP-hexose 3,5-epimerase homolog [Streptomyces cyanogenus] Length = 192 Score = 101 bits (250), Expect = 5e-21 Identities = 63/174 (36%), Positives = 93/174 (53%), Gaps = 3/174 (1%) Query: 10 IPDVILIKPKV-FEDERGFFMETYKKSDFEKA-GIKGEFVQDNHSRSKYGVLRGLHFQKE 67 +P V ++ P +DERG F E+ + + G E Q N+S S+ LRG+H Sbjct: 8 VPGVHVLAPWTGSKDERGAFFESLRTDLLQDVVGHPFEVKQINYSVSRRNHLRGIHSVTS 67 Query: 68 PYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVLSD 127 P QAK V C+RG D VDLR SPTFG++ +L + LYIP G HGFL L++ Sbjct: 68 PPGQAKYVSCVRGAFRDFVVDLRVGSPTFGQYDVNLLDAASGRALYIPEGVGHGFLTLTE 127 Query: 128 VAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPI-DNPILSEKDKKWPTLKELIE 180 A + Y + + Y P + + DPD+ + W + P++SEKD+ +L +E Sbjct: 128 DACICYVLSSTYVPGTQIDIDPLDPDLALPWGFTEPPLISEKDRTARSLAATLE 181 >pir||T51104 dTDP-4-keto-6-deoxyglucose 3,5-epimerase [validated] - Streptomyces antibioticus (ATCC 11891) >gi|5902168|gb|AAD55452.1| (AF055579) dTDP-4-keto-6-deoxyglucose 3,5-epimerase [Streptomyces antibioticus] Length = 204 Score = 101 bits (249), Expect = 6e-21 Identities = 58/159 (36%), Positives = 76/159 (47%), Gaps = 1/159 (0%) Query: 8 LSIPDVILIKPKVFEDERGFFMETYKKSDF-EKAGIKGEFVQDNHSRSKYGVLRGLHFQK 66 L + L P++ DERG F+E ++ F EK G Q N S S+ Sbjct: 4 LDVDGAWLYTPEIMRDERGEFLEWFRGRTFQEKIGHPLSLAQANCSVSRKAFCAASTSPT 63 Query: 67 EPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVLS 126 P QAK V C G + DV VD+R+ SPTFG+W V L LY+ G H F+ L+ Sbjct: 64 PPPGQAKYVTCASGTVLDVVVDVRRGSPTFGRWAAVRLDAARHQGLYLAEGLGHAFMALT 123 Query: 127 DVAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPIDNPIL 165 D A VVY Y E E + DP + I+WP D I+ Sbjct: 124 DDATVVYLCSQPYVAEAERAVDPLDPAIGIEWPTDIDIV 162 >pir||S34962 rfbD protein - Shigella dysenteriae (fragment) >gi|152777|gb|AAA16933.1| (L07293) dTDP-6-deoxy-L-lyxo-4 hexulose 4-reductase [Shigella dysenteriae] Length = 107 Score = 88.5 bits (216), Expect = 5e-17 Identities = 39/66 (59%), Positives = 48/66 (72%) Query: 94 PTFGKWVGVILSEFNKWQLYIPRGFAHGFLVLSDVAEVVYKVDNVYAPEYEGGLIWNDPD 153 PTFGKW+GV LS K QL+IP GFAHGFLVLS+ AE VYK N Y P +E + ++DP Sbjct: 15 PTFGKWIGVNLSAEIKRQLWIPEGFAHGFLVLSETAEFVYKTTNYYNPSFEKSISYSDPT 74 Query: 154 VNIKWP 159 + I+WP Sbjct: 75 IKIQWP 80 >pir||F81288 probable nucleotide-sugar epimerase/dehydratase Cj1430c [imported] - Campylobacter jejuni (strain NCTC 11168) >gi|6968859|emb|CAB73854.1| (AL139078) putative nucleotide-sugar epimerase/dehydratase [Campylobacter jejuni] Length = 181 Score = 86.2 bits (210), Expect = 2e-16 Identities = 55/163 (33%), Positives = 77/163 (46%), Gaps = 11/163 (6%) Query: 13 VILIKPKVFEDERGFFMETYKKSDFEKAGIKG-EFVQDNHSRSKYGVLRGLHFQKEPYAQ 71 V +I P F D RG + K G +F D S + VLRG+H + Y Sbjct: 16 VYIITPNKFRDLRGEIWTAFTDEYLSKLVPDGIKFKHDKFINSHFNVLRGIHGDVKTY-- 73 Query: 72 AKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVLSDVAEV 131 K+V C+ G + V VD RK+SPT+ KW I+S N+ + +P + V S A Sbjct: 74 -KLVTCVYGEVHQVVVDCRKDSPTYLKWEKFIISYKNQQLILLPPNMGNSHYVSSKEAVY 132 Query: 132 VYKVDNVYAPEY-----EGGLIWNDPDVNIKWPIDNPILSEKD 169 YK+ Y EY + WND + I WP + PILS++D Sbjct: 133 YYKL--AYEGEYMDAPDQFTYAWNDERIGIDWPTNTPILSDRD 173 >gb|AAF00208.1|AF164960_4 (AF164960) epimerase [Streptomyces fradiae] Length = 202 Score = 85.8 bits (209), Expect = 3e-16 Identities = 57/178 (32%), Positives = 80/178 (44%), Gaps = 1/178 (0%) Query: 8 LSIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEFVQDNHSRSKYGVLRGLHFQKE 67 +SIP LI P DERG F E G+ + Q N+S SK LRG+H Sbjct: 1 MSIPGAFLITPDQLSDERGAFYELRCDMLERAVGVPFQPQQINYSVSKRHTLRGIHSVSI 60 Query: 68 PYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVLSD 127 P QAK+V C+RG + D+ VDLR SP FG L + +Y+P + Sbjct: 61 PPGQAKLVTCVRGALRDIVVDLRIGSPAFGAHQVTELDAVSGRSVYVPEVWGTDSSRSPT 120 Query: 128 VAEVVYKVDNVYAPEYEGGLIWNDPDVNIKWPI-DNPILSEKDKKWPTLKELIEKDEL 184 + Y P + + DPD+++ W P++SEKD K +L E + L Sbjct: 121 TPVSATSSPSTYVPGTQIDINPLDPDLDLPWDCPQEPLISEKDAKASSLAEALASGTL 178 >gb|AAD41825.1|AF147704_5 (AF147704) NDP-hexose 3,5- (or5-) epimerase TylCVII [Streptomyces fradiae] Length = 197 Score = 83.1 bits (202), Expect = 2e-15 Identities = 57/174 (32%), Positives = 85/174 (48%), Gaps = 10/174 (5%) Query: 10 IPDVILIKPKVFEDERGFFMETYKKSDFEKA-GIKGEFVQDNHSRSKYGVLRGLHFQKEP 68 + D I P+ D RG E+ + +A G E Q NH+ ++ LRG+H P Sbjct: 8 VRDAYRITPEPIPDHRGSLYESLRYETLRRATGHAIEIRQVNHTVNRRNTLRGIHGTTVP 67 Query: 69 YAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFLVLSDV 128 Q KIV C+RG + VDLR SPTFG V + +Y+P G G++ L+D Sbjct: 68 PGQGKIVTCVRGAARTMVVDLRVGSPTFGGHDVVGQDAESGVAVYLPDGLGLGYVALADD 127 Query: 129 AEVVYKVDNVYAPEYEGGLIWN----DPDVNIKWPI-DNPILSEKDKKWPTLKE 177 + Y +Y EY G+I + DP + + W + + P+ SE+D P+L E Sbjct: 128 TCMNY----LYTREYTPGMIIDIDALDPGLGLPWNLTEPPVRSERDAAAPSLAE 177 >gb|AAD10182.1| (AF026471) Cps2M [Streptococcus pneumoniae] Length = 197 Score = 74.5 bits (180), Expect = 8e-13 Identities = 63/188 (33%), Positives = 96/188 (50%), Gaps = 19/188 (10%) Query: 9 SIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEF-----VQDNHSRSKYGVLRGLH 63 +IP ++ V D RG+F E ++K E G F +Q+N S S+ VLRGLH Sbjct: 17 AIPGMLEFDIPVHGDNRGWFKENFQKEKMEPLGFPESFFAEGKLQNNVSFSRKNVLRGLH 76 Query: 64 FQKEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFL 123 EP+ + V G + VDLR+ TFG I+ +++PRG A+GF Sbjct: 77 --AEPWDKYISV-ADGGKVLGSWVDLREGE-TFGNTYQTIIDASKG--IFVPRGVANGFQ 130 Query: 124 VLSDVAEVVYKVDNVYA----PEYEGGLIWNDPDVNIKWP-IDNPILSEKDKKWPTLKEL 178 VLSD Y V++ +A P+Y + + DP + I+W I +SE DK P LK++ Sbjct: 131 VLSDTVSYSYLVNDYWALELKPKY-AFVNYADPSLGIEWENIAEAEVSEADKHHPLLKDV 189 Query: 179 --IEKDEL 184 ++K++L Sbjct: 190 KPLKKEDL 197 >gb|AAC38694.1| (AF030363) dTDP-4-keto-6-deoxyglucose-3,5-epimerase [Streptococcus pneumoniae] Length = 197 Score = 72.2 bits (174), Expect = 4e-12 Identities = 61/188 (32%), Positives = 95/188 (50%), Gaps = 19/188 (10%) Query: 9 SIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEF-----VQDNHSRSKYGVLRGLH 63 +IP ++ V D RG+F E ++K G F +Q+N S S+ VLRGLH Sbjct: 17 AIPGMLEFDIPVHRDNRGWFKENFQKEKMLPLGFPESFFAEGKLQNNVSFSRKNVLRGLH 76 Query: 64 FQKEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFL 123 EP+ + V G + VDLR+ TFG ++ +++PRG A+GF Sbjct: 77 --AEPWDKYISV-ADGGKVLGSWVDLREGE-TFGNTYQTVIDASKG--IFVPRGVANGFQ 130 Query: 124 VLSDVAEVVYKVDNVYA----PEYEGGLIWNDPDVNIKWP-IDNPILSEKDKKWPTLKEL 178 VLSD Y V++ +A P+Y + + DP + I+W I +SE DK P LK++ Sbjct: 131 VLSDTVSYSYLVNDYWALELKPKY-AFVNYADPSLGIEWENIAEAEVSEADKNHPLLKDV 189 Query: 179 --IEKDEL 184 ++K++L Sbjct: 190 KPLKKEDL 197 >emb|CAB05931.1| (Z83335) dTDP-4-dehydrorhamnose 3,5-epimerase [Streptococcus pneumoniae] Length = 198 Score = 71.4 bits (172), Expect = 7e-12 Identities = 60/188 (31%), Positives = 96/188 (50%), Gaps = 19/188 (10%) Query: 9 SIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEF-----VQDNHSRSKYGVLRGLH 63 +IP ++ V D RG+F E ++K G F +Q+N S S+ VLRGLH Sbjct: 17 AIPGMLEFDIPVHGDNRGWFKENFQKEKVLPLGFPESFFAEGKLQNNVSFSRKNVLRGLH 76 Query: 64 FQKEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFL 123 EP+ + V G + VDLR+ TFG ++ +++PRG A+GF Sbjct: 77 --AEPWDKYISV-ADGGKVLGSWVDLREGE-TFGNTYQTVIDASKG--IFVPRGVANGFQ 130 Query: 124 VLSDVAEVVYKVDNVYA----PEYEGGLIWNDPDVNIKWP-IDNPILSEKDKKWPTLKEL 178 VLSD Y V++ +A P+Y + + DP + I+W ++ +SE DK P LK++ Sbjct: 131 VLSDTVSYSYLVNDYWALELKPKY-AFVNYADPSLGIEWENLEEADVSEADKHHPLLKDV 189 Query: 179 --IEKDEL 184 ++K++L Sbjct: 190 KPLKKEDL 197 >gb|AAC44970.1| (U09239) dTDP-4-keto-6-deoxyglucose-3,5-epimerase [Streptococcus pneumoniae] >gi|2804690|gb|AAC38678.1| (AF030360) dTDP-4-keto-6-deoxyglucose-3,5-epimerase [Streptococcus pneumoniae] >gi|2804696|gb|AAC38683.1| (AF030361) dTDP-4-keto-6-deoxyglucose-3,5-epimerase [Streptococcus pneumoniae] >gi|2804703|gb|AAC38689.1| (AF030362) dTDP-4-keto-6-deoxyglucose-3,5-epimerase [Streptococcus pneumoniae] >gi|2804715|gb|AAC38699.1| (AF030364) dTDP-4-keto-6-deoxyglucose-3,5-epimerase [Streptococcus pneumoniae] Length = 198 Score = 71.0 bits (171), Expect = 9e-12 Identities = 61/188 (32%), Positives = 95/188 (50%), Gaps = 19/188 (10%) Query: 9 SIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEF-----VQDNHSRSKYGVLRGLH 63 +IP ++ V D RG+F E ++K G F +Q+N S S+ VLRGLH Sbjct: 17 AIPGMLEFDIPVHGDNRGWFKENFQKEKMLPLGFPESFFAEGKLQNNVSFSRKNVLRGLH 76 Query: 64 FQKEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFL 123 EP+ + V G + VDLR+ TFG ++ +++PRG A+GF Sbjct: 77 --AEPWDKYISV-ADGGKVLGSWVDLREGE-TFGNTYQTVIDASKG--IFVPRGVANGFQ 130 Query: 124 VLSDVAEVVYKVDNVYA----PEYEGGLIWNDPDVNIKWP-IDNPILSEKDKKWPTLKEL 178 VLSD Y V++ +A P+Y + + DP + I+W I +SE DK P LK++ Sbjct: 131 VLSDTVSYSYLVNDYWALELKPKY-AFVNYADPSLGIEWENIAEAEVSEADKHHPLLKDV 189 Query: 179 --IEKDEL 184 ++K++L Sbjct: 190 KPLKKEDL 197 >gb|AAC69539.1| (AF057294) Cps23fP [Streptococcus pneumoniae] Length = 197 Score = 71.0 bits (171), Expect = 9e-12 Identities = 61/188 (32%), Positives = 95/188 (50%), Gaps = 19/188 (10%) Query: 9 SIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEF-----VQDNHSRSKYGVLRGLH 63 +IP ++ V D RG+F E ++K G F +Q+N S S+ VLRGLH Sbjct: 17 AIPGMLEFDIPVHGDNRGWFKENFQKEKMLPLGFPESFFAEGKLQNNVSFSRKNVLRGLH 76 Query: 64 FQKEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFL 123 EP+ + V G + VDLR+ TFG ++ +++PRG A+GF Sbjct: 77 --AEPWDKYISV-ADGGKVLGSWVDLREGE-TFGNTYQTVIDASKG--IFVPRGVANGFQ 130 Query: 124 VLSDVAEVVYKVDNVYA----PEYEGGLIWNDPDVNIKWP-IDNPILSEKDKKWPTLKEL 178 VLSD Y V++ +A P+Y + + DP + I+W I +SE DK P LK++ Sbjct: 131 VLSDTVSYSYLVNDYWALELKPKY-AFVNYADPSLGIEWENIAEAEVSEADKHHPLLKDV 189 Query: 179 --IEKDEL 184 ++K++L Sbjct: 190 KPLKKEDL 197 >gb|AAC38705.1| (AF030365) dTDP-4-keto-6-deoxyglucose-3,5-epimerase [Streptococcus pneumoniae] >gi|2804728|gb|AAC38710.1| (AF030366) dTDP-4-keto-6-deoxyglucose-3,5-epimerase [Streptococcus pneumoniae] >gi|3320400|gb|AAC38758.1| (AF030373) dTDP-4-keto-6-deoxyglucose-3,5-epimerase [Streptococcus pneumoniae] Length = 197 Score = 70.6 bits (170), Expect = 1e-11 Identities = 61/188 (32%), Positives = 95/188 (50%), Gaps = 19/188 (10%) Query: 9 SIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEF-----VQDNHSRSKYGVLRGLH 63 +IP ++ V D RG+F E ++K G F +Q+N S S+ VLRGLH Sbjct: 17 AIPCMLEFDIPVHGDNRGWFKENFQKEKMLPLGFPESFFAEGKLQNNVSFSRKNVLRGLH 76 Query: 64 FQKEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFL 123 EP+ + V G + VDLR+ TFG ++ +++PRG A+GF Sbjct: 77 --AEPWDKYISV-ADGGKVLGSWVDLREGE-TFGNTYQTVIDASKG--IFVPRGVANGFQ 130 Query: 124 VLSDVAEVVYKVDNVYA----PEYEGGLIWNDPDVNIKWP-IDNPILSEKDKKWPTLKEL 178 VLSD Y V++ +A P+Y + + DP + I+W I +SE DK P LK++ Sbjct: 131 VLSDTVSYSYLVNDYWALELKPKY-AFVNYADPSLGIEWENIAEAEVSEADKNHPLLKDV 189 Query: 179 --IEKDEL 184 ++K++L Sbjct: 190 KPLKKEDL 197 >gb|AAC78675.1| (AF094575) dTDP-4-keto-6-deoxyglucose-3,5-epimerase Cps19aM [Streptococcus pneumoniae] Length = 198 Score = 70.2 bits (169), Expect = 2e-11 Identities = 63/189 (33%), Positives = 98/189 (51%), Gaps = 21/189 (11%) Query: 9 SIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEF-----VQDNHSRSKYGVLRGLH 63 +IP ++ V D RG+F E ++K G F +Q+N S S+ VLRGLH Sbjct: 17 AIPGLLEFDIPVHGDNRGWFKENFQKEKMLPLGFPESFFAAGKLQNNVSFSRKNVLRGLH 76 Query: 64 FQKEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQ-LYIPRGFAHGF 122 EP+ + V G + VDLR+ TFG V +E + + +++PRG A+GF Sbjct: 77 --AEPWDKYISV-ADDGKVLGSWVDLREGE-TFGN---VYQTEIDASKGIFVPRGVANGF 129 Query: 123 LVLSDVAEVVYKVDNVYA----PEYEGGLIWNDPDVNIKWP-IDNPILSEKDKKWPTLKE 177 VLSD Y V++ +A P+Y + + DP + I+W I +SE DK P LK+ Sbjct: 130 QVLSDTVSYSYLVNDYWALELKPKY-AFVNYADPSLGIEWENIAEAEVSEADKNHPLLKD 188 Query: 178 L--IEKDEL 184 + ++K++L Sbjct: 189 VKPLKKEDL 197 >gb|AAC38673.1| (AF030359) dTDP-4-keto-6-deoxyglucose-3,5-epimerase [Streptococcus pneumoniae] Length = 198 Score = 69.9 bits (168), Expect = 2e-11 Identities = 61/188 (32%), Positives = 95/188 (50%), Gaps = 19/188 (10%) Query: 9 SIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEF-----VQDNHSRSKYGVLRGLH 63 +IP ++ V D RG+F E ++K G F +Q+N S S+ VLRGLH Sbjct: 17 AIPGMLEFDIPVHGDNRGWFKENFQKEKMLPLGFPESFFAEGKLQNNVSFSRKNVLRGLH 76 Query: 64 FQKEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFL 123 EP+ + V G + VDLR+ TFG ++ +++PRG A+GF Sbjct: 77 --AEPWDKYISV-ADGGKVQGSWVDLREGE-TFGNTYQTVIDASKG--IFVPRGVANGFQ 130 Query: 124 VLSDVAEVVYKVDNVYA----PEYEGGLIWNDPDVNIKWP-IDNPILSEKDKKWPTLKEL 178 VLSD Y V++ +A P+Y + + DP + I+W I +SE DK P LK++ Sbjct: 131 VLSDTVSYSYLVNDYWALELKPKY-AFVNYADPSLGIEWENIAEAEVSEADKHHPLLKDV 189 Query: 179 --IEKDEL 184 ++K++L Sbjct: 190 KPLKKEDL 197 >gb|AAD19914.1| (AF105113) dTDP-4-keto-6-deoxyglucose-3,5-epimerase [Streptococcus pneumoniae] Length = 197 Score = 69.5 bits (167), Expect = 3e-11 Identities = 63/189 (33%), Positives = 97/189 (50%), Gaps = 21/189 (11%) Query: 9 SIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEF-----VQDNHSRSKYGVLRGLH 63 +IP ++ V D RG+F E ++K G F +Q+N S S+ VLRGLH Sbjct: 17 AIPGLLEFDIPVHGDNRGWFKENFQKEKMLPLGFPESFFAAGKLQNNVSFSRKNVLRGLH 76 Query: 64 FQKEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQ-LYIPRGFAHGF 122 EP+ + V G + VDLR+ TFG V +E + + +++PRG A+GF Sbjct: 77 --AEPWDKYISV-ADDGKVLGSWVDLREGE-TFGN---VYQTEIDASKGIFVPRGVANGF 129 Query: 123 LVLSDVAEVVYKVDNVYA----PEYEGGLIWNDPDVNIKWP-IDNPILSEKDKKWPTLKE 177 VLSD Y V++ +A P+Y + + DP + I+W + +SE DK P L++ Sbjct: 130 QVLSDTVSYSYLVNDYWALELKPKY-AFVNYADPALGIEWENLPEAEVSEADKHHPLLRD 188 Query: 178 L--IEKDEL 184 + + KDEL Sbjct: 189 VKPLTKDEL 197 >dbj|BAA11248.1| (D78182) dTDP-4-keto-L-rhamnose reductase [Streptococcus mutans] Length = 198 Score = 67.9 bits (163), Expect = 8e-11 Identities = 58/180 (32%), Positives = 89/180 (49%), Gaps = 17/180 (9%) Query: 9 SIPDVILIKPKVFEDERGFFMETYKKSDFEKAGIKGEF-----VQDNHSRSKYGVLRGLH 63 +IP +I V D RG+F E ++K G F +Q+N S S+ VLRGLH Sbjct: 18 AIPGMIEFDIPVHGDNRGWFKENFQKEKMVPLGFPESFFAEGKLQNNVSFSRKNVLRGLH 77 Query: 64 FQKEPYAQAKIVRCIRGVIFDVAVDLRKNSPTFGKWVGVILSEFNKWQLYIPRGFAHGFL 123 EP+ + V G + VDLR+ +FG ++ +++PRG A+GF Sbjct: 78 --AEPWDKYISV-ADEGKVLGSWVDLREGD-SFGHVYQAVIDASKG--IFVPRGVANGFQ 131 Query: 124 VLSDVAEVVYKVDNVYA----PEYEGGLIWNDPDVNIKWP-IDNPILSEKDKKWPTLKEL 178 VLSD Y V++ +A P+Y + + DP + I+W + +SE DK P LK++ Sbjct: 132 VLSDKVSYSYLVNDYWALELKPKY-AFVNYADPTLGIEWENLAEAQVSEADKNHPLLKDV 190 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.322 0.143 0.445 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 75324820 Number of Sequences: 2977 Number of extensions: 3238301 Number of successful extensions: 6171 Number of sequences better than 1.0e-10: 92 Number of HSP's better than 0.0 without gapping: 76 Number of HSP's successfully gapped in prelim test: 16 Number of HSP's that attempted gapping in prelim test: 5965 Number of HSP's gapped (non-prelim): 92 length of query: 185 length of database: 189,106,746 effective HSP length: 49 effective length of query: 136 effective length of database: 159,780,883 effective search space: 21730200088 effective search space used: 21730200088 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.8 bits) S2: 163 (67.9 bits)