BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB0789 (PAB0789) DE:DTDP-4-DEHYDRORHAMNOSE REDUCTASE
         (283 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||G75098 dtdp-4-dehydrorhamnose reductase PAB0789 - Pyrococcu...   573  e-163
pir||B71152 probable dTDP-4-dehydrorhamnose reductase - Pyrococc...   489  e-137
gi|11500015 dTDP-4-dehydrorhamnose reductas [Archaeoglobus fulgi...   430  e-120
pir||D69106 dTDP-4-dehydrorhamnose reductase - Methanobacterium ...   253  2e-66
dbj|BAB07084.1| (AP001518) spore coat polysaccharide synthesis (...   200  2e-50
gb|AAC35923.1| (AF071085) putative dTDP-4-keto-L-rhamnose reduct...   196  2e-49
sp|P39631|SPSK_BACSU SPORE COAT POLYSACCHARIDE BIOSYNTHESIS PROT...   185  5e-46
pir||S74471 dTDP-6-deoxy-L-mannose-dehydrogenase - Synechocystis...   179  3e-44
gb|AAC44972.1| (U09239) 32.3 kDa cps19fO gene product [Streptoco...   176  2e-43
gb|AAC38675.1| (AF030359) dTDP-L-rhamnose synthase [Streptococcu...   175  4e-43
gb|AAC69541.1| (AF057294) Cps23fR [Streptococcus pneumoniae]          175  6e-43
gb|AAC78677.1| (AF094575) dTDP-L-rhamnose synthase Cps19aO [Stre...   175  6e-43
gb|AAC38691.1| (AF030362) dTDP-L-rhamnose synthase [Streptococcu...   174  1e-42
gb|AAC38680.1| (AF030360) dTDP-L-rhamnose synthase [Streptococcu...   174  1e-42
emb|CAB65207.1| (AJ007311) RmlD protein [Legionella pneumophila]      172  5e-42
pir||G72588 probable dTDP-4-dehydrorhamnose reductase APE1179 - ...   168  5e-41
gb|AAD19916.1| (AF105113) dTDP-L-rhamnose synthase [Streptococcu...   168  9e-41
gb|AAG29801.1| (AF235050) dTDP-4-keto-6-deoxyhexose reductase [S...   163  2e-39
dbj|BAA21509.1| (AB000631) dTDP-4-keto-L-rhamnose reductase [Str...   162  3e-39
gb|AAD05457.1| (AF064070) putative dTDP-4-keto-L-rhamnose reduct...   161  9e-39
emb|CAA07388.1| (AJ006985) StrL [Streptomyces glaucescens]            158  8e-38
pir||T31087 probable dTDP-L-rhamnose synthase - Serratia marcesc...   157  1e-37
sp|P55463|RFBD_RHISN PROBABLE DTDP-4-DEHYDRORHAMNOSE REDUCTASE (...   155  4e-37
gb|AAF67512.1|AF170880_19 (AF170880) NovS [Streptomyces spheroides]   155  5e-37
pir||T00104 probable dTDP-4-dehydrorhamnose reductase (EC 1.1.1....   153  2e-36
pir||C81164 dTDP-L-rhamnose synthase, probable NMB0756 [imported...   153  2e-36
sp|P29781|STRL_STRGR DTDP-4-DEHYDRORHAMNOSE REDUCTASE (DTDP-4-KE...   152  4e-36
pir||F81943 probable dTDP-4-dehydrorhamnose reductase (EC 1.1.1....   151  8e-36
gb|AAA68212.1| (L37354) thymidine diphospho-4-keto-6-deoxyglucos...   148  9e-35
pir||C83000 dTDP-4-dehydrorhamnose reductase PA5162 [imported] -...   148  9e-35
dbj|BAA82534.1| (AB030032) dTDP-4-keto-L-rhamnose reductase [Act...   146  3e-34
gb|AAF01815.1|AF187532_11 (AF187532) putative dTDP-4-dehydrorham...   145  6e-34
pir||I69649 dTDP-6-deoxy-L-mannose-dehydrogenase - Escherichia coli   143  3e-33
gb|AAG09507.1|AF279617_2 (AF279617) dTDP-6-deoxy-L-mannose-dehyd...   143  3e-33
sp|P37760|RBD1_ECOLI DTDP-4-DEHYDRORHAMNOSE REDUCTASE (DTDP-4-KE...   142  4e-33
pir||B36864 OAC2 protein - Azorhizobium caulinodans >gi|296708|e...   141  7e-33
dbj|BAA19635.1| (AB002668) dTDP-4-rhamnose reductase [Actinobaci...   141  7e-33
dbj|BAA94404.1| (AB041266) dTDP-6-deoxy-L-lyxo-4-hexulose redact...   141  9e-33
pir||C70978 probable rmlD protein - Mycobacterium tuberculosis (...   139  3e-32
gb|AAA53680.1| (L14842) dTDP-6-deoxy-D-glucose-3,5 epimerase [Sh...   137  1e-31
gb|AAF59936.1| (AF237895) 4-ketoreductase [Streptomyces antibiot...   137  2e-31
gb|AAG09531.1|AF279623_2 (AF279623) dTDP-6-deoxy-L-mannose-dehyd...   137  2e-31
gb|AAG09514.1|AF279619_2 (AF279619) dTDP-6-deoxy-L-mannose-dehyd...   136  2e-31
pir||C55213 rfbC protein - Shigella flexneri (strain 2a)              136  3e-31
gb|AAG09527.1|AF279622_2 (AF279622) dTDP-6-deoxy-L-mannose-dehyd...   136  3e-31
gb|AAG09510.1|AF279618_2 (AF279618) dTDP-6-deoxy-L-mannose-dehyd...   136  4e-31
gb|AAG09523.1|AF279621_2 (AF279621) dTDP-6-deoxy-L-mannose-dehyd...   136  4e-31
gb|AAG09503.1|AF279616_2 (AF279616) dTDP-6-deoxy-L-mannose-dehyd...   135  7e-31
gb|AAC44075.1| (U51197) dTDP-6-deoxy-L-mannose-dehydrogenase [Sp...   134  9e-31
gb|AAG09535.1|AF279624_2 (AF279624) dTDP-6-deoxy-L-mannose-dehyd...   134  9e-31
gb|AAG09499.1|AF279615_2 (AF279615) dTDP-6-deoxy-L-mannose-dehyd...   134  1e-30
gb|AAG09518.1|AF279620_2 (AF279620) dTDP-6-deoxy-L-mannose-dehyd...   134  2e-30
pir||T00085 dTDP-4-dehydrorhamnose reductase (EC 1.1.1.133) - St...   131  1e-29
sp|P26392|RFBD_SALTY DTDP-4-DEHYDRORHAMNOSE REDUCTASE (DTDP-4-KE...   131  1e-29
gb|AAG09538.1|AF279625_2 (AF279625) dTDP-6-deoxy-L-mannose-dehyd...   129  5e-29
emb|CAB01952.1| (Z79692) ExpA10 [Sinorhizobium meliloti]              128  7e-29
pir||G70346 spore coat polysaccharide biosynthesis protein SpsK ...   128  7e-29
pir||T51107 4-ketoreductase [validated] - Streptomyces antibioti...   127  1e-28
pir||S23348 hypothetical protein 5.2 - Salmonella choleraesuis >...   126  3e-28
sp|Q46769|RBD2_ECOLI DTDP-4-DEHYDRORHAMNOSE REDUCTASE (DTDP-4-KE...   123  2e-27
pir||C49906 rfbC homolog - Xanthomonas campestris pv. campestris...   119  4e-26
gb|AAB47841.1| (U61226) RfbC [Leptospira interrogans]                 118  6e-26
pir||E82828 dTDP-4-keto-L-rhamnose reductase XF0258 [imported] -...   118  7e-26
gb|AAD52187.1|AF144879_26 (AF144879) unknown [Leptospira interro...   118  1e-25
gb|AAD12970.1| (AF078135) RmlD [Leptospira borgpetersenii]            117  2e-25
sp|P37778|RFBD_SHIFL DTDP-4-DEHYDRORHAMNOSE REDUCTASE (DTDP-4-KE...   114  1e-24
emb|CAC13137.1| (AJ250139) dTDP-4-dehydrorhamnose reductase [Ace...   113  2e-24
gb|AAK41127.1| dTDP-4-dehydrorhamnose reductase (rfbD-1) [Sulfol...   109  3e-23
emb|CAB57472.1| (Y18930) dTDP-4-dehydrorhamnose reductase [Sulfo...   109  3e-23
emb|CAB56837.1| (AJ243721) dTDP-4-keto-6-deoxy-D-glucose 4-reduc...   106  4e-22
gi|11034825 dTDP-4-keto-6-deoxy-D-glucose 4-reductase; beta regu...   106  4e-22
gb|AAK41975.1| dTDP-4-dehydrorhamnose reductase (rfbD-2) [Sulfol...   100  2e-20
gb|AAC70777.1| (AF097519) dTDP-4-keto-L-rhamnose reductase [Kleb...    97  3e-19
pir||S35300 rfbG protein - Yersinia enterocolitica >gi|48591|emb...    91  2e-17
pir||F75597 dTDP-4-rhamnose reductase-related protein - Deinococ...    87  3e-16
emb|CAB56751.1| (X56616) putative dTDP-4-dehydrorhamnose reducta...    83  3e-15
gb|AAD12954.1| (AF078135) unknown [Leptospira borgpetersenii]          72  7e-12
gb|AAD52171.1|AF144879_10 (AF144879) unknown [Leptospira interro...    72  7e-12
pir||A71183 probable UDP-glucose 4-epimerase - Pyrococcus horiko...    72  9e-12
gb|AAK42337.1| dTDP-4-dehydrorhamnose reductase (rfbD-3) [Sulfol...    70  3e-11
pir||S74068 hypothetical protein c0137 - Sulfolobus solfataricus...    70  3e-11

>pir||G75098 dtdp-4-dehydrorhamnose reductase PAB0789 - Pyrococcus abyssi
           (strain Orsay) >gi|5458604|emb|CAB50092.1| (AJ248286)
           DTDP-4-DEHYDRORHAMNOSE REDUCTASE [Pyrococcus abyssi]
           Length = 283
           
 Score =  573 bits (1461), Expect = e-163
 Identities = 283/283 (100%), Positives = 283/283 (100%)

Query: 1   MRVAVIGANGQLGTDLVEVFGEEAIPLTRKDLDVTDFESLKILKELKPEVIINTAAYVRV 60
           MRVAVIGANGQLGTDLVEVFGEEAIPLTRKDLDVTDFESLKILKELKPEVIINTAAYVRV
Sbjct: 1   MRVAVIGANGQLGTDLVEVFGEEAIPLTRKDLDVTDFESLKILKELKPEVIINTAAYVRV 60

Query: 61  DDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNPINV 120
           DDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNPINV
Sbjct: 61  DDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNPINV 120

Query: 121 YGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIVNDQ 180
           YGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIVNDQ
Sbjct: 121 YGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIVNDQ 180

Query: 181 FMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFEILGWDVRVKPINSS 240
           FMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFEILGWDVRVKPINSS
Sbjct: 181 FMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFEILGWDVRVKPINSS 240

Query: 241 ELKRLAKRPKFSALKNEKLEKIGLKMKHWKEALGEYLKEKGYL 283
           ELKRLAKRPKFSALKNEKLEKIGLKMKHWKEALGEYLKEKGYL
Sbjct: 241 ELKRLAKRPKFSALKNEKLEKIGLKMKHWKEALGEYLKEKGYL 283


>pir||B71152 probable dTDP-4-dehydrorhamnose reductase - Pyrococcus horikoshii
           >gi|3256820|dbj|BAA29503.1| (AP000002) 290aa long
           hypothetical dTDP-4-dehydrorhamnose reductase
           [Pyrococcus horikoshii]
           Length = 290
           
 Score =  489 bits (1245), Expect = e-137
 Identities = 234/287 (81%), Positives = 261/287 (90%), Gaps = 4/287 (1%)

Query: 1   MRVAVIGANGQLGTDLVEVFGE----EAIPLTRKDLDVTDFESLKILKELKPEVIINTAA 56
           MR+A+IGANGQLGTDLVEVFG     E +PLT KDLDVT  ESLK+LKE+KP+V+INTAA
Sbjct: 4   MRIAIIGANGQLGTDLVEVFGNDPEFEVVPLTHKDLDVTIPESLKVLKEIKPDVLINTAA 63

Query: 57  YVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPN 116
           YVRVDDAELYPE+AF VNAIGALNVARIANEI A+NVYISTDYVFDG KGEPYTEED+PN
Sbjct: 64  YVRVDDAELYPEKAFAVNAIGALNVARIANEIDAVNVYISTDYVFDGEKGEPYTEEDVPN 123

Query: 117 PINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRI 176
           PINVYG SKY GEIFTRNYS K+YIIRVASLYGKAGA GKGGNFVEWVI+KA  GEEL+I
Sbjct: 124 PINVYGVSKYTGEIFTRNYSPKHYIIRVASLYGKAGASGKGGNFVEWVIEKAKHGEELKI 183

Query: 177 VNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFEILGWDVRVKP 236
           V+DQFMSPTYTKDVARTL+E L+LR  FGVYHMVNEG+CSWYEFT AIF++LGW+V +KP
Sbjct: 184 VDDQFMSPTYTKDVARTLKEFLKLRSEFGVYHMVNEGFCSWYEFTEAIFDVLGWNVEIKP 243

Query: 237 INSSELKRLAKRPKFSALKNEKLEKIGLKMKHWKEALGEYLKEKGYL 283
           I S+EL RLAKRP+FSALKNEKLEKIGL+M+HW+EAL EYLKEKGY+
Sbjct: 244 IKSNELNRLAKRPRFSALKNEKLEKIGLRMRHWREALEEYLKEKGYV 290


>gi|11500015 dTDP-4-dehydrorhamnose reductas [Archaeoglobus fulgidus]
           Length = 285
           
 Score =  430 bits (1095), Expect = e-120
 Identities = 205/283 (72%), Positives = 243/283 (85%), Gaps = 2/283 (0%)

Query: 1   MRVAVIGANGQLGTDLVEVFGEE--AIPLTRKDLDVTDFESLKILKELKPEVIINTAAYV 58
           M+VAVIGA GQLGTDLV+V  EE    PLT +D+DV   ESL++L+++ P+VIINTAAYV
Sbjct: 1   MKVAVIGAKGQLGTDLVDVLKEEFTVYPLTHEDVDVAVSESLEVLRDIHPDVIINTAAYV 60

Query: 59  RVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNPI 118
           RVDDAE + E+AF VNAIGALNVARI++EI A+N+YISTDYVFDG KGEPY E D PNPI
Sbjct: 61  RVDDAENHAEKAFAVNAIGALNVARISSEIDAVNIYISTDYVFDGEKGEPYVETDKPNPI 120

Query: 119 NVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIVN 178
           NVYGASKY GEI T+NYS+K+Y+IRVASLYGKAGA GKGGNFV WV+  A KG+ELRIV 
Sbjct: 121 NVYGASKYAGEILTKNYSEKHYVIRVASLYGKAGASGKGGNFVNWVVDMARKGQELRIVA 180

Query: 179 DQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFEILGWDVRVKPIN 238
           DQFMSPTYTKDVA  +RE L+LRP +G+YHMVN+GYCSW+EFT+AIFEIL WDV ++PI 
Sbjct: 181 DQFMSPTYTKDVALAVREFLKLRPDYGIYHMVNDGYCSWFEFTKAIFEILDWDVEIQPIK 240

Query: 239 SSELKRLAKRPKFSALKNEKLEKIGLKMKHWKEALGEYLKEKG 281
           SSEL RLA+RP FSAL+N KLE+IG+KM+HW+EAL +YL EKG
Sbjct: 241 SSELNRLARRPAFSALQNYKLERIGIKMRHWREALRDYLAEKG 283


>pir||D69106 dTDP-4-dehydrorhamnose reductase - Methanobacterium
           thermoautotrophicum (strain Delta H)
           >gi|2622923|gb|AAB86258.1| (AE000933)
           dTDP-4-dehydrorhamnose reductase [Methanobacterium
           thermoautotrophicum]
           Length = 280
           
 Score =  253 bits (639), Expect = 2e-66
 Identities = 120/285 (42%), Positives = 191/285 (66%), Gaps = 8/285 (2%)

Query: 1   MRVAVIGANGQLGTDLVEVFGEEAIPLTRKDLDVTDFES-LKILKELKPEVIINTAAYVR 59
           M++ + G++G LG+DLV++       +T   LD+ D E  +++L+E +P+ +++ AA+  
Sbjct: 1   MKILITGSSGMLGSDLVDILSRRHEVVTSGSLDIRDLEGVMELLRETRPDAVVHAAAFTD 60

Query: 60  VDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNPIN 119
           VD AE   ++A++VN +G  N+A  A+ +G+  +YISTDYVFDG KG+ Y E D PNP+N
Sbjct: 61  VDCAETERDKAYQVNVLGTRNIAAAASAVGSSILYISTDYVFDGEKGDGYLEFDEPNPLN 120

Query: 120 VYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIVND 179
            YG +KY+GE+  R  S+++YI+R + L+G+      G NFV  +++ A +G E+ +V+D
Sbjct: 121 FYGKTKYLGEVSVRQLSERFYIVRTSWLFGR-----NGRNFVGTMVELAERGHEISVVDD 175

Query: 180 QFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFEILGWDVRVKPINS 239
           Q+ SPTYT+D+A  +  LL  RP++GVYH+ N G CSWYEF   IF  LG +V +KP+ S
Sbjct: 176 QYGSPTYTRDLAAAIGNLLE-RPAYGVYHLTNSGQCSWYEFAIDIFNELGMEVCLKPVKS 234

Query: 240 SELKRLAKRPKFSALKNEKLEKIGLK-MKHWKEALGEYLKEKGYL 283
            E  R A+RP FS L+N      G K ++++++AL +YLK+ G++
Sbjct: 235 HEFPRPARRPSFSVLRNYNWSMEGFKPLRNYRDALRDYLKDAGFV 279


>dbj|BAB07084.1| (AP001518) spore coat polysaccharide synthesis
           (dTDP-4-dehydrorhamnose reductase) [Bacillus halodurans]
           Length = 283
           
 Score =  200 bits (503), Expect = 2e-50
 Identities = 112/281 (39%), Positives = 171/281 (59%), Gaps = 12/281 (4%)

Query: 5   VIGANGQLGTDLVEVFGE--EAIPLTRKDLDVTDFES-LKILKELKPEVIINTAAYVRVD 61
           + GANGQ+G +L +   +  +   LT+++L++ D  + +  +K + P+ II+ AA+  VD
Sbjct: 6   ITGANGQVGMELSKQGKQHFQVTALTKQELNILDRNTVMNKIKGVNPDWIIHVAAFTAVD 65

Query: 62  DAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNPINVY 121
             E    +A+ VN +GA NVAR A E GA  +YISTDYVFDG K  PY   D+PNP+NVY
Sbjct: 66  QCEDEQRKAYHVNGLGAANVARAARETGAKLIYISTDYVFDGNKNSPYETCDLPNPLNVY 125

Query: 122 GASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIVNDQF 181
           G SK++GE   + Y K   I R + LYG       GGNFV+ +++   KGE + +V DQ 
Sbjct: 126 GNSKWLGERLVQKYVKTCTIARTSWLYGH-----YGGNFVKTMLRLLRKGEPIEVVADQV 180

Query: 182 MSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFEILGWDVR-VKPINSS 240
             PTY  D+   L  L+  +PS G+YH+ N G C+W+EF RAI +  G+D   ++   + 
Sbjct: 181 GCPTYVNDLVYYLFALME-KPS-GIYHISNRGSCNWFEFARAIAKNAGYDPSLIRATTTK 238

Query: 241 ELKRLAKRPKFSALKNEKLEKIGLK-MKHWKEALGEYLKEK 280
                A+RPK+S + +++LE  GL+  + W+ AL E+++E+
Sbjct: 239 AFAAKARRPKYSVMSHQQLELAGLQPPREWELALKEFIQEE 279


>gb|AAC35923.1| (AF071085) putative dTDP-4-keto-L-rhamnose reductase [Enterococcus
           faecalis]
           Length = 299
           
 Score =  196 bits (494), Expect = 2e-49
 Identities = 112/282 (39%), Positives = 168/282 (58%), Gaps = 13/282 (4%)

Query: 3   VAVIGANGQLGTDLVEVFGEEAIPLTRKD---LDVTDFES-LKILKELKPEVIINTAAYV 58
           + + G NGQLGT+L  +  E+ I     D   LD+TD +S L  +KE++P VI + AAY 
Sbjct: 21  ILITGGNGQLGTELRHLLDEQGIEYVSTDSTELDITDADSTLAKVKEIQPSVIYHCAAYT 80

Query: 59  RVDDAELYPEEAF-KVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEP-YTEEDIPN 116
            VD AE   +E   KVN  G  +VA  A  +GA  VY+STDY+FDG K E  Y  +D PN
Sbjct: 81  AVDKAEDEGKELDEKVNVDGTRHVAEAAKAVGATLVYVSTDYIFDGTKKEGVYAIDDQPN 140

Query: 117 PINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRI 176
           P+N YG +K +GE   +     YYIIR + ++G+ G      NFV  + K A   ++L +
Sbjct: 141 PLNEYGRTKLLGEQAVQEILDDYYIIRTSWVFGQYGH-----NFVFTMQKLAETRDQLTV 195

Query: 177 VNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFEILGWDVRVKP 236
           V+DQF  PT+T+ +A  +  ++  +  FGVYH+ NE  CSWY+F + I +    +V V P
Sbjct: 196 VDDQFGRPTWTRTLAEFMAFVIAEKAPFGVYHLSNENSCSWYQFAKEILK--DTEVEVLP 253

Query: 237 INSSELKRLAKRPKFSALKNEKLEKIGLKMKHWKEALGEYLK 278
           ++S++  + A+RP++S +   K E +G K+  W+EAL + L+
Sbjct: 254 VDSTQFPQKAQRPQYSVMDLSKTEALGFKIPTWQEALAQMLE 295


>sp|P39631|SPSK_BACSU SPORE COAT POLYSACCHARIDE BIOSYNTHESIS PROTEIN SPSK
           >gi|2126975|pir||S39728 spore coat polysaccharide
           synthesis spsK - Bacillus subtilis
           >gi|580881|emb|CAA51629.1| (X73124) ipa-73d [Bacillus
           subtilis] >gi|2636317|emb|CAB15808.1| (Z99123) alternate
           gene name: ipa-73d [Bacillus subtilis]
           Length = 432
           
 Score =  185 bits (465), Expect = 5e-46
 Identities = 104/264 (39%), Positives = 155/264 (58%), Gaps = 11/264 (4%)

Query: 2   RVAVIGANGQLGTDL---VEVFGEEAIPLTRKDLDVTDFESLK-ILKELKPEVIINTAAY 57
           +V V GA GQLG +L   ++  G E I LT+K +++ D  S++      +P++++N+AA+
Sbjct: 3   KVLVTGAGGQLGLELCRQLKQAGYEVIALTKKMMNIADQRSVRHSFGHYQPDIVVNSAAF 62

Query: 58  VRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNP 117
             VD  E   ++A+ +N IGA   A  +  IGA  V+ISTDYVF+G   +PY E+D  +P
Sbjct: 63  TSVDQCEKELDKAYLINGIGAYYTALESTRIGAQYVHISTDYVFNGKGTQPYREDDPLDP 122

Query: 118 INVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIV 177
             +YG SK +GE   R  +K   IIR + +YG  G+     NFVE ++K A   +ELR+V
Sbjct: 123 KTIYGKSKRLGEELIRLTTKDSTIIRTSWVYGHGGS-----NFVETMLKLAETKQELRVV 177

Query: 178 NDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFEILGWDVRVKPI 237
           +DQ  SPTYTKD+A  + +L    P  G+YH+ N G CSWYEF  AI E  G +  +  +
Sbjct: 178 SDQIGSPTYTKDLAEAVIKLFSHPP--GIYHVSNSGICSWYEFATAIMEESGLETAILSV 235

Query: 238 NSSELKRLAKRPKFSALKNEKLEK 261
            + E      RP +S L +  +E+
Sbjct: 236 TTEEYGNKTPRPAYSVLSHRAIEE 259


>pir||S74471 dTDP-6-deoxy-L-mannose-dehydrogenase - Synechocystis sp.  (strain
           PCC 6803) >gi|1651695|dbj|BAA16623.1| (D90899)
           dTDP-6-deoxy-L-mannose-dehydrogenase [Synechocystis sp.]
           Length = 280
           
 Score =  179 bits (450), Expect = 3e-44
 Identities = 106/275 (38%), Positives = 158/275 (56%), Gaps = 22/275 (8%)

Query: 22  EEAIPL---------TRKDLDVTDFESL-KILKELKPEVIINTAAYVRVDDAELYPEEAF 71
           E AIPL         TR   D+   + L + ++   P++I+N+AAY  VD AE  PE A+
Sbjct: 4   ELAIPLSCFGSVQEATRASFDLAQPDVLGEKIRAFAPDIIVNSAAYTAVDRAETEPELAY 63

Query: 72  KVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNPINVYGASKYIGEIF 131
            VNA+    +A++A EIGA  V+ISTDYVFDG++  PY E D  NP+ VYG SK+ GEI 
Sbjct: 64  AVNALAPQAIAKVAKEIGAYVVHISTDYVFDGSQSSPYRETDATNPLGVYGQSKFQGEIA 123

Query: 132 TRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIVNDQFMSPTYTKDVA 191
             +    + I+R A +YG  G+    GNFV+ +++   + +++R+V DQ   PT+ KD+A
Sbjct: 124 IADSGCNFLIVRTAWVYGVHGS----GNFVKTMVRLGKERQKVRVVADQIGGPTWAKDLA 179

Query: 192 RTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIF---EILGWDVRVK---PINSSELKRL 245
             +  L   R   G+YH  N G  SWY+F  AIF   E LG  ++V+   PI ++     
Sbjct: 180 EAIAALTEQRAQ-GIYHYSNSGVASWYDFAVAIFEEVENLGIPLKVRQVVPIATAAYPTP 238

Query: 246 AKRPKFSALKNEKL-EKIGLKMKHWKEALGEYLKE 279
           A+RP +S L ++K+ E +G    HW+ +L   L +
Sbjct: 239 ARRPAYSVLSHQKIVETLGSAPPHWRASLRAMLHQ 273


>gb|AAC44972.1| (U09239) 32.3 kDa cps19fO gene product [Streptococcus pneumoniae]
           Length = 283
           
 Score =  176 bits (443), Expect = 2e-43
 Identities = 107/287 (37%), Positives = 163/287 (56%), Gaps = 16/287 (5%)

Query: 3   VAVIGANGQLGTDL---VEVFGEEAIPLTRKDLDVTDFESL-KILKELKPEVIINTAAYV 58
           + + GANGQLGT+L   ++   EE + +   ++D+TD E + K+ +E+KP ++ + AAY 
Sbjct: 2   ILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITDAEMVEKVFEEVKPTLVYHCAAYT 61

Query: 59  RVDDAELYPEEA-FKVNAIGALNVARIANEIGAINVYISTDYVFDGAK--GEPYTEEDIP 115
            VD AE   +E  F +N  G  NVAR + + GA  VYISTDYVFDG K  G+ +  +D P
Sbjct: 62  AVDAAEDEGKELDFAINVTGTKNVARASEKHGATLVYISTDYVFDGKKPVGQEWEVDDRP 121

Query: 116 NPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELR 175
           +P   YG +K +GE     +   +YIIR A ++G  G      NFV  +   A   + L 
Sbjct: 122 DPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGK-----NFVFTMQNLAKTHKTLT 176

Query: 176 IVNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGY--CSWYEFTRAIFEILGWDVR 233
           +VNDQ+  PT+T+ +A  +  L   R  FG YH+ N+     +WY+F  A+  +   DV 
Sbjct: 177 VVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDTTWYDF--AVEILKDTDVE 234

Query: 234 VKPINSSELKRLAKRPKFSALKNEKLEKIGLKMKHWKEALGEYLKEK 280
           VKP++SS+    AKRP  S +   K +  G  +  W++AL E+ K++
Sbjct: 235 VKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQEFYKQE 281


>gb|AAC38675.1| (AF030359) dTDP-L-rhamnose synthase [Streptococcus pneumoniae]
           >gi|2804698|gb|AAC38685.1| (AF030361) dTDP-L-rhamnose
           synthase [Streptococcus pneumoniae]
           >gi|2804717|gb|AAC38701.1| (AF030364) dTDP-L-rhamnose
           synthase [Streptococcus pneumoniae]
           >gi|4200436|gb|AAD10184.1| (AF026471) Cps2O
           [Streptococcus pneumoniae]
           Length = 283
           
 Score =  175 bits (440), Expect = 4e-43
 Identities = 106/287 (36%), Positives = 163/287 (55%), Gaps = 16/287 (5%)

Query: 3   VAVIGANGQLGTDL---VEVFGEEAIPLTRKDLDVTDFESL-KILKELKPEVIINTAAYV 58
           + + GANGQLGT+L   ++   EE + +   ++D+TD E + K+ +E+KP ++ + AAY 
Sbjct: 2   ILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITDAEMVEKVFEEVKPTLVYHCAAYT 61

Query: 59  RVDDAELYPEEA-FKVNAIGALNVARIANEIGAINVYISTDYVFDGAK--GEPYTEEDIP 115
            VD AE   +E  F +N  G  NVA+ + + GA  VYISTDYVFDG K  G+ +  +D P
Sbjct: 62  AVDAAEDEGKELDFAINVTGTKNVAKASEKHGATLVYISTDYVFDGKKPVGQEWEVDDRP 121

Query: 116 NPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELR 175
           +P   YG +K +GE     +   +YIIR A ++G  G      NFV  +   A   + L 
Sbjct: 122 DPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGK-----NFVFTMQNLAKTHKTLT 176

Query: 176 IVNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGY--CSWYEFTRAIFEILGWDVR 233
           +VNDQ+  PT+T+ +A  +  L   R  FG YH+ N+     +WY+F  A+  +   DV 
Sbjct: 177 VVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDTTWYDF--AVEILKDTDVE 234

Query: 234 VKPINSSELKRLAKRPKFSALKNEKLEKIGLKMKHWKEALGEYLKEK 280
           VKP++SS+    AKRP  S +   K +  G  +  W++AL E+ K++
Sbjct: 235 VKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQEFYKQE 281


>gb|AAC69541.1| (AF057294) Cps23fR [Streptococcus pneumoniae]
           Length = 283
           
 Score =  175 bits (439), Expect = 6e-43
 Identities = 106/287 (36%), Positives = 163/287 (55%), Gaps = 16/287 (5%)

Query: 3   VAVIGANGQLGTDL---VEVFGEEAIPLTRKDLDVTDFESL-KILKELKPEVIINTAAYV 58
           + + GANGQLGT+L   ++   EE + +   ++D+TD E + K+ +E+KP ++ + AAY 
Sbjct: 2   ILITGANGQLGTELRYLLDERNEEYVAVDVVEMDITDAEMVEKVFEEVKPTLVYHCAAYT 61

Query: 59  RVDDAELYPEEA-FKVNAIGALNVARIANEIGAINVYISTDYVFDGAK--GEPYTEEDIP 115
            VD AE   +E  F +N  G  NVA+ + + GA  VYISTDYVFDG K  G+ +  +D P
Sbjct: 62  AVDAAEDEGKELDFAINVTGTKNVAKASEKHGATLVYISTDYVFDGKKPVGQEWEVDDRP 121

Query: 116 NPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELR 175
           +P   YG +K +GE     +   +YIIR A ++G  G      NFV  +   A   + L 
Sbjct: 122 DPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGK-----NFVFTMQNLAKTHKTLT 176

Query: 176 IVNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGY--CSWYEFTRAIFEILGWDVR 233
           +VNDQ+  PT+T+ +A  +  L   R  FG YH+ N+     +WY+F  A+  +   DV 
Sbjct: 177 VVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDTTWYDF--AVEILKDTDVE 234

Query: 234 VKPINSSELKRLAKRPKFSALKNEKLEKIGLKMKHWKEALGEYLKEK 280
           VKP++SS+    AKRP  S +   K +  G  +  W++AL E+ K++
Sbjct: 235 VKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQEFYKQE 281


>gb|AAC78677.1| (AF094575) dTDP-L-rhamnose synthase Cps19aO [Streptococcus
           pneumoniae]
           Length = 283
           
 Score =  175 bits (439), Expect = 6e-43
 Identities = 106/287 (36%), Positives = 162/287 (55%), Gaps = 16/287 (5%)

Query: 3   VAVIGANGQLGTDL---VEVFGEEAIPLTRKDLDVTDFESL-KILKELKPEVIINTAAYV 58
           + + GANGQLGT+L   ++   EE + +   ++D+TD E + K+ +E+KP ++ + AAY 
Sbjct: 2   ILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITDAEMVEKVFEEVKPTLVYHCAAYT 61

Query: 59  RVDDAELYPEEA-FKVNAIGALNVARIANEIGAINVYISTDYVFDGAK--GEPYTEEDIP 115
            VD AE    E  F +N  G  NVA+ + + GA  VYISTDYVFDG K  G+ +  +D P
Sbjct: 62  AVDAAEDEGRELDFAINVTGTKNVAKASEKHGATLVYISTDYVFDGKKPVGQEWEVDDRP 121

Query: 116 NPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELR 175
           +P   YG +K +GE     +   +YIIR A ++G  G      NFV  +   A   + L 
Sbjct: 122 DPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGK-----NFVFTMQNLAKTHKTLT 176

Query: 176 IVNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGY--CSWYEFTRAIFEILGWDVR 233
           +VNDQ+  PT+T+ +A  +  L   R  FG YH+ N+     +WY+F  A+  +   DV 
Sbjct: 177 VVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDTTWYDF--AVEILKDTDVE 234

Query: 234 VKPINSSELKRLAKRPKFSALKNEKLEKIGLKMKHWKEALGEYLKEK 280
           VKP++SS+    AKRP  S +   K +  G  +  W++AL E+ K++
Sbjct: 235 VKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQEFYKQE 281


>gb|AAC38691.1| (AF030362) dTDP-L-rhamnose synthase [Streptococcus pneumoniae]
           >gi|2804711|gb|AAC38696.1| (AF030363) dTDP-L-rhamnose
           synthase [Streptococcus pneumoniae]
           >gi|2804724|gb|AAC38707.1| (AF030365) dTDP-L-rhamnose
           synthase [Streptococcus pneumoniae]
           >gi|2804730|gb|AAC38712.1| (AF030366) dTDP-L-rhamnose
           synthase [Streptococcus pneumoniae]
           >gi|3320402|gb|AAC38760.1| (AF030373) dTDP-L-rhamnose
           synthase [Streptococcus pneumoniae]
           Length = 283
           
 Score =  174 bits (437), Expect = 1e-42
 Identities = 106/287 (36%), Positives = 163/287 (55%), Gaps = 16/287 (5%)

Query: 3   VAVIGANGQLGTDL---VEVFGEEAIPLTRKDLDVTDFESL-KILKELKPEVIINTAAYV 58
           + + GANGQLGT+L   ++   EE + +   ++D+T+ E + K+ +E+KP ++ + AAY 
Sbjct: 2   ILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITNEEMVEKVFEEVKPTLVYHCAAYT 61

Query: 59  RVDDAELYPEEA-FKVNAIGALNVARIANEIGAINVYISTDYVFDGAK--GEPYTEEDIP 115
            VD AE   +E  F +N  G  NVAR + + GA  VYISTDYVFDG K  G+ +  +D P
Sbjct: 62  AVDAAEDEGKELDFAINVTGTKNVARASEKHGATLVYISTDYVFDGKKPVGQEWEVDDRP 121

Query: 116 NPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELR 175
           +P   YG +K +GE     +   +YIIR A ++G  G      NFV  +   A   + L 
Sbjct: 122 DPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGK-----NFVFTMQNLAKTHKTLT 176

Query: 176 IVNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGY--CSWYEFTRAIFEILGWDVR 233
           +VNDQ+  PT+T+ +A  +  L   R  FG YH+ N+     +WY+F  A+  +   DV 
Sbjct: 177 VVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDTTWYDF--AVEILKDTDVE 234

Query: 234 VKPINSSELKRLAKRPKFSALKNEKLEKIGLKMKHWKEALGEYLKEK 280
           VKP++SS+    AKRP  S +   K +  G  +  W++AL E+ K++
Sbjct: 235 VKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQEFYKQE 281


>gb|AAC38680.1| (AF030360) dTDP-L-rhamnose synthase [Streptococcus pneumoniae]
           Length = 283
           
 Score =  174 bits (436), Expect = 1e-42
 Identities = 105/287 (36%), Positives = 162/287 (55%), Gaps = 16/287 (5%)

Query: 3   VAVIGANGQLGTDL---VEVFGEEAIPLTRKDLDVTDFESL-KILKELKPEVIINTAAYV 58
           + + G NGQLGT+L   ++   EE + +   ++D+TD E + K+ +E+KP ++ + AAY 
Sbjct: 2   ILITGTNGQLGTELRYLLDERNEEYVAVDVAEMDITDAEMVEKVFEEVKPTLVYHCAAYT 61

Query: 59  RVDDAELYPEEA-FKVNAIGALNVARIANEIGAINVYISTDYVFDGAK--GEPYTEEDIP 115
            VD AE   +E  F +N  G  NVA+ + + GA  VYISTDYVFDG K  G+ +  +D P
Sbjct: 62  AVDAAEDEGKELDFAINVTGTKNVAKASEKHGATLVYISTDYVFDGKKPVGQEWEVDDRP 121

Query: 116 NPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELR 175
           +P   YG +K +GE     +   +YIIR A ++G  G      NFV  +   A   + L 
Sbjct: 122 DPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGK-----NFVFTMQNLAKTHKTLT 176

Query: 176 IVNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGY--CSWYEFTRAIFEILGWDVR 233
           +VNDQ+  PT+T+ +A  +  L   R  FG YH+ N+     +WY+F  A+  +   DV 
Sbjct: 177 VVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDTTWYDF--AVEILKDTDVE 234

Query: 234 VKPINSSELKRLAKRPKFSALKNEKLEKIGLKMKHWKEALGEYLKEK 280
           VKP++SS+    AKRP  S +   K +  G  +  W++AL E+ K++
Sbjct: 235 VKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQEFYKQE 281


>emb|CAB65207.1| (AJ007311) RmlD protein [Legionella pneumophila]
           Length = 294
           
 Score =  172 bits (431), Expect = 5e-42
 Identities = 108/293 (36%), Positives = 162/293 (54%), Gaps = 21/293 (7%)

Query: 1   MRVAVIGANGQLGTDLVEVFGE---EAIPLTRKDLDVTDFESLK-ILKELKPEVIINTAA 56
           M++ V GANGQ+GT++++ F     E    TR  LD +  E +  +L E+KP++IIN AA
Sbjct: 1   MKILVTGANGQVGTEIIKRFSSSEHEVYACTRDILDCSKLERVHDVLSEIKPDLIINAAA 60

Query: 57  YVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPN 116
           Y  VD AE  P+ A  VNA     +           +++STDYVFDG K   Y E DIP+
Sbjct: 61  YTAVDKAEDEPDLAHIVNAEFVCRLVNYCTLKNVPLIHLSTDYVFDGEKEGAYHETDIPH 120

Query: 117 PINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRI 176
           P++ YG +K+ GE    +  KKY I+RV+ ++G+     +G NFV+ ++  A+  +EL I
Sbjct: 121 PVSTYGRTKWEGEQAILSQLKKYIILRVSWVFGE-----QGKNFVKTILNLASSRKELNI 175

Query: 177 VNDQFMSPTYTKDVARTLRELL-RLRPS----FGVYHMVNEGYCSWYEFTRAIF------ 225
           V+DQ   PT  +D+AR L E++ ++R S    +G+YH   +G  +W+EF           
Sbjct: 176 VSDQSGRPTSARDIARVLFEIVQKIRHSSFDYWGLYHYAGQGVTNWHEFANVFLNMAKEK 235

Query: 226 EILGWDVRVKPINSSELKRLAKRPKFSALKNEKLEKI-GLKMKHWKEALGEYL 277
           ++L     + PI S E    A RPK S L   K+E I G+K   WK  L + +
Sbjct: 236 QLLLTLTDLNPIKSQEYPTRATRPKNSVLDTTKIETILGIKSCSWKNDLPDVI 288


>pir||G72588 probable dTDP-4-dehydrorhamnose reductase APE1179 - Aeropyrum
           pernix (strain K1) >gi|5104851|dbj|BAA80165.1|
           (AP000061) 305aa long hypothetical
           dTDP-4-dehydrorhamnose reductase [Aeropyrum pernix]
           Length = 305
           
 Score =  168 bits (422), Expect = 5e-41
 Identities = 108/298 (36%), Positives = 172/298 (57%), Gaps = 28/298 (9%)

Query: 1   MRVAVIGANGQLGTDLVEVF---GEEAIPLTRKD------------LDVTDFESL-KILK 44
           +++ V G  G LG +LV+     G    P   K+            +++ D   L ++ +
Sbjct: 6   LKLLVTGGTGLLGYNLVQQLLKKGYSVYPTYNKNTPFKLAGARWSKVNLEDPSQLTQLFR 65

Query: 45  ELKPEVIINTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGA 104
           ++KP+ +I+TAAY  VD  EL+ E A+++N + ++ VAR+A   G++ +Y+STDYVFDG 
Sbjct: 66  DIKPDAVIHTAAYTDVDGCELHRERAYRINFLASMTVARLAARHGSLLIYVSTDYVFDGD 125

Query: 105 KGEPYTEEDIPNPINVYGASKYIGEIFTRNYSKK--YYIIRVASLYG--KAGARGKGGNF 160
           KG  Y EE+ PNPIN YG SK +GE+ T +   K    ++RV+ LYG    G R  G N 
Sbjct: 126 KG-MYREEEAPNPINYYGLSKLLGEVATLSAMDKENVLVVRVSGLYGYSPTGKRNFGIN- 183

Query: 161 VEWVIKKANKGEELRIVNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEF 220
              V++K  +GEE+R   DQ++SPTYT  ++R L ++L  R   GV H+  E   S  EF
Sbjct: 184 ---VLEKLLRGEEVRAFYDQYLSPTYTYFLSRRLIDVLE-REIRGVLHLAGE-RLSRLEF 238

Query: 221 TRAIFEILGWDVR-VKPINSSELKRLAKRPKFSALKNEKLEKIGLKMKHWKEALGEYL 277
            + I ++LG D   +KPI+  E    A+RP+ S+L     +K+GL++   +E++  ++
Sbjct: 239 AQLIAKVLGADAELIKPISMKEANLPARRPRDSSLDTTMAKKLGLELPSQEESVKHFV 296


>gb|AAD19916.1| (AF105113) dTDP-L-rhamnose synthase [Streptococcus pneumoniae]
           Length = 284
           
 Score =  168 bits (420), Expect = 9e-41
 Identities = 102/287 (35%), Positives = 161/287 (55%), Gaps = 16/287 (5%)

Query: 3   VAVIGANGQLGTDLVEVFGEEAIPLTRKD---LDVTDFESL-KILKELKPEVIINTAAYV 58
           + + GANGQLGT+L  +  E  +     D   +D+T+ E + K+  E+KP ++ + AAY 
Sbjct: 2   ILITGANGQLGTELRYLLNERNVDYVAVDVTEMDITNSEMVEKVFAEVKPTLVYHCAAYT 61

Query: 59  RVDDAELYPEEA-FKVNAIGALNVARIANEIGAINVYISTDYVFDGAK--GEPYTEEDIP 115
            VD AE   +E  F +N  G  NVA+ + + GAI VYISTDYVFDG K  G+ +  +DIP
Sbjct: 62  AVDAAEDEGKELDFAINVTGTENVAKGSEKYGAILVYISTDYVFDGKKPVGQEWEVDDIP 121

Query: 116 NPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELR 175
           +P   YG +K +GE    N + ++YIIR A ++G  G      NFV  +   A   + L 
Sbjct: 122 DPQTEYGRTKRMGEELVENLTSQHYIIRTAWVFGNYGR-----NFVFTMQSLAETHKTLT 176

Query: 176 IVNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGY--CSWYEFTRAIFEILGWDVR 233
           +V+DQ+  PT+T+ +A  +  +   +  +G YH+ N+     +WY+F   I +    DV 
Sbjct: 177 VVSDQYGRPTWTRTLAEFMTYVTENQKEYGYYHLSNDAAEDTTWYDFASEILK--ESDVE 234

Query: 234 VKPINSSELKRLAKRPKFSALKNEKLEKIGLKMKHWKEALGEYLKEK 280
           + P++SS+    AKRP  S +   K +  G  +  W++AL E+ K++
Sbjct: 235 LLPVDSSKFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALKEFYKQE 281


>gb|AAG29801.1| (AF235050) dTDP-4-keto-6-deoxyhexose reductase [Streptomyces
           rishiriensis]
           Length = 288
           
 Score =  163 bits (409), Expect = 2e-39
 Identities = 100/279 (35%), Positives = 152/279 (53%), Gaps = 13/279 (4%)

Query: 2   RVAVIGANGQLGTDLV---EVFGEEAIPLTRKDLDVTDFESLK-ILKELKPEVIINTAAY 57
           R  V GA G LG DLV   E   E  +  TR+DLD+TD  S++ ++   +P  I+N AA+
Sbjct: 4   RWLVTGAGGMLGRDLVRVLEALNEPVLAATRQDLDITDRFSVRAVVSRYRPTAIVNCAAW 63

Query: 58  VRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNP 117
            R  +AE    EA  +N  GA  +A I  +     V++STDYVFDGA   PY E     P
Sbjct: 64  TRFHEAETSEAEAHLINGRGARELATICGDRSIRLVHLSTDYVFDGASRRPYAESAATGP 123

Query: 118 INVYGASKYIGE-IFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRI 176
           IN YG +K  GE            I+R A LYG+ G      NF+  +++     + + +
Sbjct: 124 INAYGRTKLAGEQAVLELLPDDGTIVRTAWLYGRHGT-----NFLRKMVRLEQTHKTVDV 178

Query: 177 VNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFEILGWDV-RVK 235
           V+DQ+  PT++ D+A+ +  L+R   S GV+H  + G  +WY+F R IF +LG D  R++
Sbjct: 179 VDDQWGQPTWSVDLAQQIVALVRHGAS-GVFHGTSSGETTWYDFARMIFRLLGADPGRIR 237

Query: 236 PINSSELKRLAKRPKFSALKNEKLEKIGL-KMKHWKEAL 273
           P+ S ++     RP+++ L +    ++GL  ++HW  AL
Sbjct: 238 PVRSDQIAGGELRPRYTVLGHAAWREVGLTPIRHWSAAL 276


>dbj|BAA21509.1| (AB000631) dTDP-4-keto-L-rhamnose reductase [Streptococcus mutans]
           Length = 284
           
 Score =  162 bits (407), Expect = 3e-39
 Identities = 99/286 (34%), Positives = 155/286 (53%), Gaps = 16/286 (5%)

Query: 3   VAVIGANGQLGTDLVEVFGE---EAIPLTRKDLDVTDFESL-KILKELKPEVIINTAAYV 58
           + + G+NGQLGT+L  +  E   + + +   ++D+T  E + ++  ++KP ++ + AAY 
Sbjct: 2   ILITGSNGQLGTELRHLLNERNEDYVAVDVAEMDITKAEKVDEVFLQVKPSLVYHCAAYT 61

Query: 59  RVDDAELYPEEA-FKVNAIGALNVARIANEIGAINVYISTDYVFDGAK--GEPYTEEDIP 115
            VD AE   +E  + +N  G  N+A+   +  A  VYISTDYVFDG K  G+ +  +D P
Sbjct: 62  AVDAAEDEGKELDYAINVTGTENIAKACEKYNATLVYISTDYVFDGEKPVGQEWEVDDKP 121

Query: 116 NPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELR 175
           +P   YG +K +GE     Y K +YIIR A ++G  G      NFV  +   A     L 
Sbjct: 122 DPKTEYGRTKRLGEEAVEKYVKNFYIIRTAWVFGNYGK-----NFVFTMQHLAKSHNSLT 176

Query: 176 IVNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGY--CSWYEFTRAIFEILGWDVR 233
           +VNDQ   PT+T+ +A  +  L   +  +G YH+ N+     +WY+F   I +    DV 
Sbjct: 177 VVNDQHGRPTWTRTLAEFMTYLAENQKEYGYYHLSNDATEDTTWYDFALEILK--DTDVV 234

Query: 234 VKPINSSELKRLAKRPKFSALKNEKLEKIGLKMKHWKEALGEYLKE 279
           VKP++SS+    AKRP  S +   K +  G  +  W+EAL E+ K+
Sbjct: 235 VKPVDSSQFPAKAKRPLNSTMSLTKAKATGFVIPTWQEALQEFYKQ 280


>gb|AAD05457.1| (AF064070) putative dTDP-4-keto-L-rhamnose reductase [Burkholderia
           pseudomallei]
           Length = 298
           
 Score =  161 bits (403), Expect = 9e-39
 Identities = 106/297 (35%), Positives = 158/297 (52%), Gaps = 31/297 (10%)

Query: 1   MRVAVIGANGQLGTDLVE---VFGEEAIPLTRKDLDVTDFESL-KILKELKPEVIINTAA 56
           M++ V GANGQ+G +L     V G+  +PLTR+  D+   E+L +I+++ KP+V++N AA
Sbjct: 1   MKILVTGANGQVGWELARSLAVLGQ-VVPLTREQADLGRPETLARIVEDAKPDVVVNAAA 59

Query: 57  YVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPN 116
           Y  VD AE     A  +N      +A     +G + V+ STDYVFDG K  PY E D   
Sbjct: 60  YTAVDAAETDGAAANVINGEAVGVLAAATKRVGGLFVHYSTDYVFDGTKPSPYIETDPTC 119

Query: 117 PINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRI 176
           P+N YGASK +GE+        +   R   ++    ARGK  NF+  +++ A + EE++I
Sbjct: 120 PVNAYGASKLLGELAVAETGGDWLTFRTTWVF---AARGK--NFLRTMLRLAKEREEMKI 174

Query: 177 VNDQFMSPTYTKDVA--------RTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFEIL 228
           V DQF +PT+ + +A          +RE      + GVYHM + G  SW+ F  AI  I 
Sbjct: 175 VADQFGAPTWARSIADGTAHALTTAMRERAAGAFTSGVYHMTSAGQTSWHGFADAI--IA 232

Query: 229 GWDV----------RVKPINSSELKRLAKRPKFSALKNEKL-EKIGLKMKHWKEALG 274
            W            R+ PI +S     A+RP  S L N+ L E+ G+++  W+ A+G
Sbjct: 233 SWRAAPGAAPLAVSRIVPIPASAYPVPAQRPANSVLSNKALKERFGIELPDWRYAVG 289


>emb|CAA07388.1| (AJ006985) StrL [Streptomyces glaucescens]
           Length = 305
           
 Score =  158 bits (395), Expect = 8e-38
 Identities = 108/286 (37%), Positives = 143/286 (49%), Gaps = 17/286 (5%)

Query: 2   RVAVIGANGQLGTDLVEVFGEEAIPLT----RKDLDVTDFESLK-ILKELKPEVIINTAA 56
           R  V GA+G LG +L        +P+     R DLDVTD  + + +L   +P V++N AA
Sbjct: 8   RWLVTGASGMLGRELTARLSRRGVPVVPLVRRADLDVTDPAAARALLARHRPAVLVNCAA 67

Query: 57  YVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPN 116
           +  VD AE +   A  VN  G  ++AR     G   + +STDYVF G    PY E+D P 
Sbjct: 68  WTAVDAAEAHEARALAVNGEGPGHLARACRATGTRMIQLSTDYVFAGLADRPYREDDPPA 127

Query: 117 PINVYGASKYIGE-IFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELR 175
           P   YG +K  GE           Y++R A LYG  GA     NFV  +I+ A     + 
Sbjct: 128 PRTAYGRTKLAGERAVLDTLPDGGYVVRTAWLYGSGGA-----NFVSTMIRLAAAEGTVP 182

Query: 176 IVNDQFMSPTYTKDVARTLREL----LRLRPSFGVYHMVNEGYCSWYEFTRAIFEILGWD 231
           +V+DQ   PT+T D+A  L  L    LR     GVYH VN G  +W+   R IF   G D
Sbjct: 183 VVDDQHGGPTWTGDLADRLLALGAAALRGTAPPGVYHAVNAGSTTWHALAREIFRRAGAD 242

Query: 232 V-RVKPINSSELKRLAKRPKFSALKNEKLEKIGL-KMKHWKEALGE 275
             RV+PI S EL R A RP +S L   +    GL  ++ W+ AL E
Sbjct: 243 PGRVRPIGSGELARPAARPPYSVLAQGRWRAAGLAPLRDWRAALAE 288


>pir||T31087 probable dTDP-L-rhamnose synthase - Serratia marcescens
           >gi|2662408|gb|AAC00179.1| (AF038816) putative
           dTDP-L-rhamnose synthase [Serratia marcescens]
           Length = 288
           
 Score =  157 bits (394), Expect = 1e-37
 Identities = 99/283 (34%), Positives = 151/283 (52%), Gaps = 15/283 (5%)

Query: 1   MRVAVIGANGQLGTDLVEVFGEE--AIPLTRKDLDVTDFESLKI-LKELKPEVIINTAAY 57
           MRV + GA GQLG  +++ F      + +  + LD+ D  ++   +++L P+ IIN AAY
Sbjct: 1   MRVLLTGAAGQLGRCIIDRFPANWTLVAMDSQQLDIADSAAVSATVEQLVPDAIINAAAY 60

Query: 58  VRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNP 117
             VD AE  PE+A  +NA G   +A  A ++    ++ISTDYVFDG   EPY EE   +P
Sbjct: 61  TAVDKAESEPEKARAINAFGPGFLAAAAAKLDIPFIHISTDYVFDGTSSEPYCEETPCSP 120

Query: 118 INVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIV 177
            +VYG +K  GE+     + K  +IR A ++ +      G NFV+ +++   +  EL +V
Sbjct: 121 KSVYGQTKLEGELAALQANPKTVVIRTAWVFSE-----YGNNFVKTMLRVGAQRGELGVV 175

Query: 178 NDQFMSPTYTKDVARTLRELL-RLRPSFGVYHMVNEGYCSWYEFTRAIFEILGWDVR--- 233
           +DQ   PTY  D+A T+  +L   +  +G+YH   +   SW++F  AIF       R   
Sbjct: 176 SDQLGCPTYAGDIAATVIAMLSHPQLPYGIYHYCGDNAVSWFDFGCAIFREAETSTRYPH 235

Query: 234 ---VKPINSSELKRLAKRPKFSALKNEKLEKIGLKMKHWKEAL 273
              VKPI + E    A RP +S L   K+  + LK   W++ L
Sbjct: 236 KVSVKPIATHEYPTPASRPAYSILSTSKICALALKPSPWEQQL 278


>sp|P55463|RFBD_RHISN PROBABLE DTDP-4-DEHYDRORHAMNOSE REDUCTASE (DTDP-4-KETO-L-RHAMNOSE
           REDUCTASE) (DTDP-6-DEOXY-L-MANNOSE DEHYDROGENASE)
           (DTDP-L-RHAMNOSE SYNTHETASE) >gi|2182409|gb|AAB91681.1|
           (AE000074) Y4gG [Rhizobium sp. NGR234]
           Length = 296
           
 Score =  155 bits (389), Expect = 4e-37
 Identities = 98/286 (34%), Positives = 155/286 (53%), Gaps = 19/286 (6%)

Query: 1   MRVAVIGANGQLGTDLVEVFGE--EAIPLTRKDLDVTDFESL-KILKELKPEVIINTAAY 57
           MR+AV G NGQ+   L        E + L R + D+    ++   +++  P++I++ AAY
Sbjct: 1   MRLAVTGKNGQIALALKAQARPDVEILTLGRPNFDLACRSTVASSIRDAAPDIIVSLAAY 60

Query: 58  VRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNP 117
             VD AE  P EAF VN  G   +A  A  +G   +++STDYVFDGAK  PY EED   P
Sbjct: 61  TAVDKAESEPYEAFAVNRDGVQALAEAAAGLGVPVIHLSTDYVFDGAKPVPYCEEDRTGP 120

Query: 118 INVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIV 177
           I+VYG SK  GE    + +  + I+R + +Y + G      NFV+ +++ A+  +EL +V
Sbjct: 121 ISVYGRSKLEGEFAVASANPNHTILRTSWVYSRYGQ-----NFVKKMLRLADTNDELNVV 175

Query: 178 NDQFMSPTYTKDVARTLRELLRLRPSF------GVYHMVNEGYCSWYEFTRAIF----EI 227
            DQ   PT   D++  +  + R   S       G++H+   G  SW  F + +F    EI
Sbjct: 176 ADQLGCPTSADDISVAVMTIARRMLSSSSADLRGIFHLSGSGEASWAAFAKYVFSVYDEI 235

Query: 228 LGWDVRVKPINSSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEA 272
            G  ++V  I+++E    A+RP  S L  +KLE+  G+++ +W+E+
Sbjct: 236 TGRQIKVHDISAAEYPTPARRPANSRLHCDKLERTFGIRLPNWEES 281


>gb|AAF67512.1|AF170880_19 (AF170880) NovS [Streptomyces spheroides]
           Length = 288
           
 Score =  155 bits (388), Expect = 5e-37
 Identities = 98/279 (35%), Positives = 150/279 (53%), Gaps = 13/279 (4%)

Query: 2   RVAVIGANGQLGTDLVEVF---GEEAIPLTRKDLDVTDFESLK-ILKELKPEVIINTAAY 57
           R  V GA G LG DLV +     E  + +TR DLD+TD  S++ ++   +P  I+N AA+
Sbjct: 4   RWLVTGAAGMLGRDLVALLRGLNEPVVAITRHDLDITDRLSVRAVVDRHRPTTIVNCAAW 63

Query: 58  VRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNP 117
            R  +AE     A  VN  GA  +A +  +     V++STDYVFDG    PY E  + +P
Sbjct: 64  TRFGEAEAGESAALLVNGGGARELAAVCRDRSIRLVHLSTDYVFDGTSRRPYAESAVTSP 123

Query: 118 INVYGASKYIGEIFTRN-YSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRI 176
           IN YG +K  GE    +       I+R A LYG+ G      NF+  +++     E + +
Sbjct: 124 INAYGRTKQAGEQAVLDLLPDDGTIVRTAWLYGRHGM-----NFIRKMVRLEQLRETVDV 178

Query: 177 VNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFEILGWDV-RVK 235
           V+DQ+  PT+T D+A+ +  L+R   S GV+H  + G  +WY+  R  F +LG D  RV+
Sbjct: 179 VDDQWGQPTWTVDLAQQIVALVRHGAS-GVFHGTSAGEATWYDLARMTFRLLGADPGRVR 237

Query: 236 PINSSELKRLAKRPKFSALKNEKLEKIGL-KMKHWKEAL 273
           P+ S  +     RP+++ L ++   + GL  ++HW  AL
Sbjct: 238 PVPSDRIAGGELRPRYTVLGHDAWREAGLTPIRHWTTAL 276


>pir||T00104 probable dTDP-4-dehydrorhamnose reductase (EC 1.1.1.133) -
           Actinobacillus actinomycetemcomitans
           >gi|3132256|dbj|BAA28133.1| (AB010415)
           dTDP-4-keto-L-rhamnose reductase [Actinobacillus
           actinomycetemcomitans]
           Length = 294
           
 Score =  153 bits (383), Expect = 2e-36
 Identities = 101/289 (34%), Positives = 149/289 (50%), Gaps = 22/289 (7%)

Query: 2   RVAVIGANGQLGTDLVEVFGE----EAIPLTRKDLDVTDFESL-KILKELKPEVIINTAA 56
           R+ + GA GQLG  L ++  +    E + L   +LD+T+ + +  I+   KP VIIN AA
Sbjct: 3   RLLITGAGGQLGRSLAKLLVDNGRYEVLALDFSELDITNKDMVFSIIDSFKPNVIINAAA 62

Query: 57  YVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPN 116
           Y  VD AEL    A+ VN  G   +A  A    +  +++STDYVFDG K   Y E DI +
Sbjct: 63  YTSVDQAELEVSSAYSVNVRGVQYLAEAAIRHNSAILHVSTDYVFDGYKSGKYKETDIIH 122

Query: 117 PINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRI 176
           P+ VYG SK  GE      S K  I+R +  +G+      G NFV+ +++ A   + L +
Sbjct: 123 PLCVYGKSKAEGERLLLTLSPKSIILRTSWTFGE-----YGNNFVKTMLRLAKNRDILGV 177

Query: 177 VNDQFMSPTYTKDVARTLRELLRL-----RPSFGVYHMVNEGYCSWYEFTRAIFE----- 226
           V DQ   PTY+ D+A  L ++           +G+YH   E   SWY+F  AIF+     
Sbjct: 178 VADQIGGPTYSGDIASVLIQIAEKIIVGETVKYGIYHFTGEPCVSWYDFAIAIFDEAVAQ 237

Query: 227 -ILGWDVRVKPINSSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEAL 273
            +L     V  I +++   LAKRP  S L   K+++  G++   W+ AL
Sbjct: 238 KVLENVPLVNAITTADYPTLAKRPANSCLDLTKIQQAFGIQPSDWQRAL 286


>pir||C81164 dTDP-L-rhamnose synthase, probable NMB0756 [imported] - Neisseria
           meningitidis (group B strain MD58)
           >gi|7225985|gb|AAF41169.1| (AE002429) dTDP-L-rhamnose
           synthase, putative [Neisseria meningitidis MC58]
           Length = 306
           
 Score =  153 bits (383), Expect = 2e-36
 Identities = 99/284 (34%), Positives = 143/284 (49%), Gaps = 16/284 (5%)

Query: 1   MRVAVIGANGQLGTDLVEVFGE--EAIPLTRKDLDVTDFESL-KILKELKPEVIINTAAY 57
           MR+ + G+  QL   L +   E  E I      LD+TD +++  ++K  +P+ I+NTAAY
Sbjct: 1   MRILLTGSKSQLARCLRDRLPEDWETIATDSASLDITDADAVCNMVKSFQPDAIVNTAAY 60

Query: 58  VRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNP 117
             VD AE     AF VNA    N+A  A+   A  ++ISTDYVFDG    PY E D  NP
Sbjct: 61  TAVDKAEGDAAAAFAVNASAVYNLALAAHRAHARFIHISTDYVFDGKGKRPYQESDFTNP 120

Query: 118 INVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIV 177
            NVYG SK  GE+   + +    I+R + L+ +      G NF+  ++  A +   L  V
Sbjct: 121 SNVYGQSKTAGELLALSANPDSLILRTSWLFSE-----YGDNFIRTMLNLARERSPLSAV 175

Query: 178 NDQFMSPTYTKDVARTLRELLR-LRPSFGVYHMVNEGYCSWYEFTRAIFEILGWDVRVKP 236
           ++Q   PTY  D++ T+  LL+   P  G+YH       SWYEF + IF+         P
Sbjct: 176 HNQIGCPTYAGDLSATIIRLLQHSNPVRGIYHYAGSKSVSWYEFAQHIFQAASQQQTSFP 235

Query: 237 ------INSSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEAL 273
                 ++  E    A RP +S L   K+E   G+K   W++AL
Sbjct: 236 VPELTAVSDKEYPTAAPRPAYSILDCRKIENDFGIKPSDWQKAL 279


>sp|P29781|STRL_STRGR DTDP-4-DEHYDRORHAMNOSE REDUCTASE (DTDP-4-KETO-L-RHAMNOSE REDUCTASE)
           (DTDP-6-DEOXY-L-MANNOSE DEHYDROGENASE) (DTDP-L-RHAMNOSE
           SYNTHETASE) >gi|68281|pir||SYSMPG dTDP-dihydrostreptose
           synthase - Streptomyces griseus
           >gi|49013|emb|CAA44443.1| (X62567) dTDP-dihydrostreptose
           synthase [Streptomyces griseus]
           Length = 304
           
 Score =  152 bits (381), Expect = 4e-36
 Identities = 102/285 (35%), Positives = 146/285 (50%), Gaps = 16/285 (5%)

Query: 2   RVAVIGANGQLGTDLVEVF---GEEAIPLTRKDLDVTDFESLK-ILKELKPEVIINTAAY 57
           R  V GA+G LG +L  +    G     L R  LD+TD  +++  + E +P V++N AA+
Sbjct: 8   RWLVTGASGMLGRELTPLLDRRGAAVTALGRGHLDITDGAAVRSAVAEHRPAVVVNCAAW 67

Query: 58  VRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNP 117
             VD+AE  P  A  VN  G  ++A+    +GA+ + +STDYVF G+ G PY E+    P
Sbjct: 68  TAVDEAESEPALAMAVNGEGPRHLAQACRAVGAVLLQLSTDYVFPGSGGRPYREDHPTGP 127

Query: 118 INVYGASKYIGE-IFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRI 176
             VYG +K  GE           YI+R A LYG  G      NFV  +I+     + + +
Sbjct: 128 RTVYGCTKRAGERAVLEVLPDTGYIVRTAWLYGAGGP-----NFVAKMIRLEADEDTVLV 182

Query: 177 VNDQFMSPTYTKDVARTLREL----LRLRPSFGVYHMVNEGYCSWYEFTRAIFEILGWD- 231
           V+DQ   PT+T D+A  L  L    L      G+YH  N G  +W       F +LG D 
Sbjct: 183 VDDQHGQPTWTADLADRLAALGAAALAGTAPAGIYHATNTGGTTWNALAPETFRLLGADP 242

Query: 232 VRVKPINSSELKRLAKRPKFSALKNEKLEKIGLK-MKHWKEALGE 275
            RV+P  S  L R A RP++S L   + +  GL+ ++HW+ AL E
Sbjct: 243 ARVRPTTSLALARPAVRPRYSVLDQSRWKAAGLEPLRHWRAALTE 287


>pir||F81943 probable dTDP-4-dehydrorhamnose reductase (EC 1.1.1.133) NMA0967
           [imported] - Neisseria meningitidis (group A strain
           Z2491) >gi|7379670|emb|CAB84237.1| (AL162754) putative
           dTDP-4-dehydrorhamnose reductase [Neisseria meningitidis
           Z2491]
           Length = 287
           
 Score =  151 bits (378), Expect = 8e-36
 Identities = 99/290 (34%), Positives = 145/290 (49%), Gaps = 16/290 (5%)

Query: 1   MRVAVIGANGQLGTDLVEVFGE--EAIPLTRKDLDVTDFESL-KILKELKPEVIINTAAY 57
           MR+ + G+  QL   L +   E  E I      LD+TD +++  ++K  +P+ I+NTAAY
Sbjct: 1   MRILLTGSKSQLARCLRDRLPEDWETIATDSASLDITDADAVCNMVKSFQPDAIVNTAAY 60

Query: 58  VRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNP 117
             VD AE     AF VNA    N+A  A+   A  ++ISTDY+FDG    PY E D  NP
Sbjct: 61  TAVDKAEGDAAAAFAVNASAVYNLALAAHRAHARFIHISTDYIFDGKGKRPYQESDFTNP 120

Query: 118 INVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIV 177
            NVYG SK  GE+   + +    I+R + L+ +      G NFV  ++  A +   L  V
Sbjct: 121 SNVYGQSKTAGELLALSANPDSLILRTSWLFSE-----YGDNFVRTMLNLARERSPLSAV 175

Query: 178 NDQFMSPTYTKDV-ARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFEILGWDVRVKP 236
           ++Q   PTY  D+ A  +R L +  P  G+YH V     SWYEF + IF+         P
Sbjct: 176 HNQIGCPTYAGDLSAAIIRLLQQSNPVRGIYHYVGGKSVSWYEFAQHIFQAASQQQTSFP 235

Query: 237 ------INSSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEALGEYLKE 279
                 ++  E    A RP +S L   K+E    +K   W++AL + + +
Sbjct: 236 VPELTAVSDKEYPTAAPRPAYSILDCRKIENDFSIKPSDWQKALAQVVSK 285


>gb|AAA68212.1| (L37354) thymidine diphospho-4-keto-6-deoxyglucose 3, 5-epimerase
           [Saccharopolyspora erythraea]
           Length = 307
           
 Score =  148 bits (369), Expect = 9e-35
 Identities = 102/294 (34%), Positives = 147/294 (49%), Gaps = 27/294 (9%)

Query: 1   MRVAVIGANGQLGTDLVEVFGEEAIPLTRK----DLDVTDFESLKIL----------KEL 46
           + V V G  GQ+G++L  +    +  L       +LDVTD E++              +L
Sbjct: 6   LAVLVPGGRGQVGSELRRIVSGWSGALVHAPGSGELDVTDAEAVADAVDSFAETARDSDL 65

Query: 47  KPEVIINTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKG 106
           +P V++N AAY  VD AE  P+ +  +N  GA  +A      G   ++ISTDYVF G   
Sbjct: 66  RP-VVVNAAAYTAVDAAEEEPDRSAAINVAGAAALADACGRRGVPLLHISTDYVFPGDAT 124

Query: 107 EPYTEEDIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIK 166
            PY  +D   P   YG +K  GE    +   + +++R A +YG  G      NFV+ + +
Sbjct: 125 RPYEPDDETGPRTSYGRTKLDGERAVLDSGARAWVVRTAWVYGAGGK-----NFVKTMAR 179

Query: 167 KANKGEELRIVNDQFMSPTYTKDVARTLRELL-----RLRPSFGVYHMVNEGYCSWYEFT 221
             ++ + L +V+DQ   PT+  D+A  L EL      R  P   V H VN G  SW+EF 
Sbjct: 180 LESERDTLSVVDDQVGCPTWAADLAAGLLELAGRVAERKGPEQRVLHCVNGGQSSWFEFA 239

Query: 222 RAIFEILGWD-VRVKPINSSELKRLAKRPKFSALKNEKLEKIGL-KMKHWKEAL 273
           RA+F  LG D  RV+P +S E    A RP +S L     E  GL  ++HW+EAL
Sbjct: 240 RAVFAELGADPERVRPCSSEEFPLPAPRPAYSVLSGRAWEASGLTPLRHWREAL 293


>pir||C83000 dTDP-4-dehydrorhamnose reductase PA5162 [imported] - Pseudomonas
           aeruginosa (strain PAO1)
           >gi|9951464|gb|AAG08547.1|AE004929_2 (AE004929)
           dTDP-4-dehydrorhamnose reductase [Pseudomonas
           aeruginosa]
           Length = 302
           
 Score =  148 bits (369), Expect = 9e-35
 Identities = 100/298 (33%), Positives = 157/298 (52%), Gaps = 25/298 (8%)

Query: 2   RVAVIGANGQLGTDLVEVFGE--EAIPLTRKDLDVTDFESL-KILKELKPEVIINTAAYV 58
           R+ ++GANGQ+G +L        E +   R+  D+ D E L ++++  +P+ I+N  AY 
Sbjct: 3   RILLLGANGQVGWELQRALAPLGELLVCDRRRADLADPEGLARLVRAERPQFIVNAGAYT 62

Query: 59  RVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNPI 118
            VD AE   + A  +NA     +A  A   GA  V+ STDYVFDGA   P+ E+    P+
Sbjct: 63  AVDKAESDADNARLINARAVAVLAEEAAACGAWLVHYSTDYVFDGAGSVPFAEDAPTGPL 122

Query: 119 NVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIVN 178
           +VYG +K  GE   R    ++ I R + +Y       +GGNF + +++ A + +EL++V 
Sbjct: 123 SVYGQTKLEGEQAIRASGCRHLIFRTSWVYA-----ARGGNFAKTMLRLAGQRDELKVVA 177

Query: 179 DQFMSPTYTKDVAR-TLRELLRL-------RPSFGVYHMVNEGYCSWYEFTRAIFEIL-- 228
           DQF +PT  + +A  T + L RL         + G YH+V  G  SW+ + R + E    
Sbjct: 178 DQFGAPTSAELIADVTAQALQRLCWDVELAARASGTYHLVASGETSWHLYARFVIEQALE 237

Query: 229 -GWDV-----RVKPINSSELKRLAKRPKFSALKNEKLEKI-GLKMKHWKEALGEYLKE 279
            GW++     RV PI + +    AKRP  S L N KL+++ GL +  W+   G  ++E
Sbjct: 238 RGWELQATPQRVLPIATEDYPVPAKRPANSRLDNRKLQQVFGLVLPDWRYHAGRMIQE 295


>dbj|BAA82534.1| (AB030032) dTDP-4-keto-L-rhamnose reductase [Actinobacillus
           actinomycetemcomitans]
           Length = 292
           
 Score =  146 bits (364), Expect = 3e-34
 Identities = 92/284 (32%), Positives = 149/284 (52%), Gaps = 20/284 (7%)

Query: 5   VIGANGQLGTDLVEVFG--EEAIPLTRKDLDVTDFESLK-ILKELKPEVIINTAAYVRVD 61
           + GANGQ+G  L +      E + +   +LD+T+  ++K  +K  +P+V+IN AA+  VD
Sbjct: 6   ITGANGQVGHCLTQQLQGKHEILAVDHDELDITNQSAVKKTVKNFRPDVVINAAAHTAVD 65

Query: 62  DAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNPINVY 121
            AE   E +  +N  G   +A  A  +GA  ++ISTDYVFDG +   Y E D  +P ++Y
Sbjct: 66  RAETEIELSEAINVKGPQYLAEAAKSVGAAILHISTDYVFDGRRAGKYKETDATDPQSIY 125

Query: 122 GASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIVNDQF 181
           G +K  GE      + K+ ++R A ++ +      G NFV+ +++ A   + L +V DQ 
Sbjct: 126 GKTKLAGEQAVVEANDKFIVLRTAWVFCE-----HGSNFVKTMLRLAKTRDTLGVVADQI 180

Query: 182 MSPTYTKDVARTLRELLR-----LRPSFGVYHMVNEGYCSWYEFTRAIFE------ILGW 230
             PTY  D+A  L ++           +G+YH   E Y SW +F RAIF+      +L  
Sbjct: 181 GGPTYAGDIAAALIQIAEKIIAGKSVEYGIYHFTGEPYVSWCDFARAIFDEAVSQNMLEK 240

Query: 231 DVRVKPINSSELKRLAKRPKFSALKNEKLEKI-GLKMKHWKEAL 273
              V  I +++    AKRP  S L   K++++ G++   W+ AL
Sbjct: 241 VPLVNAITTADYPTPAKRPANSCLDLTKIQQVFGIQPSDWQRAL 284


>gb|AAF01815.1|AF187532_11 (AF187532) putative dTDP-4-dehydrorhamnose reductase [Streptomyces
           nogalater]
           Length = 291
           
 Score =  145 bits (362), Expect = 6e-34
 Identities = 92/263 (34%), Positives = 141/263 (52%), Gaps = 11/263 (4%)

Query: 23  EAIPLTRKDLDVTDFESLKI-LKELKPEVIINTAAYVRVDDAELYPEEAFKVNAIGALNV 81
           EA+ L R+ LD+TD  ++       +P V++N AA+  VD AE    EA +VN  G   +
Sbjct: 21  EAVVLGRRALDITDGRAVDAAFAAHRPRVVVNCAAFTDVDGAESRWAEAMRVNGGGPRLL 80

Query: 82  ARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNPINVYGASKYIGEIFTRN-YSKKYY 140
           AR     G   +++STDYVF G    PY E D P P  VYG SK  GE    +       
Sbjct: 81  ARRCARHGVRLIHVSTDYVFPGDTRSPYGESDAPGPRTVYGRSKLAGERAVLSLLPDTGT 140

Query: 141 IIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIVNDQFMSPTYTKDVARTLRELLRL 200
           ++R A LYG     G+G +FV  ++++A     + +VNDQ+  PT+  DVAR L  L R 
Sbjct: 141 VVRTAWLYG-----GQGRSFVRTMLERAPDDGHVDVVNDQWGQPTWAGDVARLLVTLART 195

Query: 201 RP--SFGVYHMVNEGYCSWYEFTRAIFEILGWD-VRVKPINSSELKRLAKRPKFSALKNE 257
            P  + G++H  N G  +WYE  R +F + G D  RV+P+ +++    A RP  + L ++
Sbjct: 196 PPDRARGIFHATNAGAATWYELAREVFRLAGADPERVRPVATADRPGPAPRPACTVLGHD 255

Query: 258 KLEKIGL-KMKHWKEALGEYLKE 279
           +   +G+   + W+ AL E +++
Sbjct: 256 RWRLVGVAPPRDWRAALREAMRQ 278


>pir||I69649 dTDP-6-deoxy-L-mannose-dehydrogenase - Escherichia coli
           Length = 299
           
 Score =  143 bits (356), Expect = 3e-33
 Identities = 93/298 (31%), Positives = 148/298 (49%), Gaps = 25/298 (8%)

Query: 1   MRVAVIGANGQLGTDLVEVFGEEAIPLTRKDLDVTDFES--------LKILKELKPEVII 52
           M + + G  GQ+G +L          L   D+  TD+           + ++ ++P++I+
Sbjct: 1   MNILLFGKTGQVGWELQRALAPLG-NLIAFDVHSTDYCGDFSNPEGVAETVRSIRPDIIV 59

Query: 53  NTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEE 112
           N AA+  VD AE  PE A  +NA     +A+ ANE+GA  ++ STDYVF G    P+ E 
Sbjct: 60  NAAAHTAVDKAESEPEFAQLINATSVEAIAKAANEVGAWVIHYSTDYVFPGNGDMPWLET 119

Query: 113 DIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGE 172
           D   P+NVYG +K  GE   + Y  K+ I R + +Y      GKG NF + +++ A + E
Sbjct: 120 DATAPLNVYGETKLAGEKALQEYCAKHLIFRTSWVYA-----GKGNNFAKTMLRLAKERE 174

Query: 173 ELRIVNDQFMSPT----YTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFE-- 226
           EL ++NDQF +PT         A  +R  L      G+YH+V  G  +WY+++  +FE  
Sbjct: 175 ELAVINDQFGAPTGAELLADCTAHAIRVALNKPDVAGLYHLVASGTTTWYDYSALVFEEA 234

Query: 227 -ILGWDVRVKPIN---SSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEALGEYLKE 279
              G  + +  +N   ++     A+RP  S L  EK ++   L +  W+  +   L E
Sbjct: 235 RKAGIPLALNKLNAVPTTAYPTPARRPHNSRLNTEKFQQNFALVLPDWQVGVKRMLNE 292


>gb|AAG09507.1|AF279617_2 (AF279617) dTDP-6-deoxy-L-mannose-dehydrogenase [Salmonella
           enterica]
           Length = 299
           
 Score =  143 bits (356), Expect = 3e-33
 Identities = 97/298 (32%), Positives = 156/298 (51%), Gaps = 25/298 (8%)

Query: 1   MRVAVIGANGQLGTDL----VEVFGEEAIPLTRKDLDVTDFESLK----ILKELKPEVII 52
           M + + G  GQ+G +L      V    A+ +  K+    DF + K     +++L+P+VI+
Sbjct: 1   MNILLFGKTGQVGWELQRSLAPVGNLIALDVHSKEF-CGDFSNPKGVVETVRKLRPDVIV 59

Query: 53  NTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEE 112
           N AA+  VD AE  PE A  +NA     +A+ ANE GA  V+ STDYVF G    P+ E 
Sbjct: 60  NAAAHTAVDKAESEPELAQLLNATSVEAIAKAANETGAWVVHYSTDYVFPGTGDIPWQET 119

Query: 113 DIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGE 172
           DI +P+NVYG +K  GE   ++   K+ I R + +Y      GKG NF + +++ A + +
Sbjct: 120 DITSPLNVYGKTKLTGEKALQDNCPKHLIFRTSWVYA-----GKGNNFAKTMLRLAKERQ 174

Query: 173 ELRIVNDQFMSPTYTKDVARTLRELLRL---RPSF-GVYHMVNEGYCSWYEFTRAIFE-- 226
            L ++NDQ+ +PT  + +A      +R+   +P   G+YH+V  G  +WY++   +F+  
Sbjct: 175 TLSVINDQYGAPTGAELLADCTAHAIRMAFKKPEVAGLYHLVAGGTTTWYDYAALVFDEA 234

Query: 227 ----ILGWDVRVKPINSSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEALGEYLKE 279
               I      +K + +S  + LA RP  S L  EK ++  GL +  W+  +   L E
Sbjct: 235 RKAGITLALTELKAVPTSAYQTLASRPGNSRLNTEKFQRNFGLILPQWELGVKRMLTE 292


>sp|P37760|RBD1_ECOLI DTDP-4-DEHYDRORHAMNOSE REDUCTASE (DTDP-4-KETO-L-RHAMNOSE REDUCTASE)
           (DTDP-6-DEOXY-L-MANNOSE DEHYDROGENASE) (DTDP-L-RHAMNOSE
           SYNTHETASE) >gi|7436796|pir||G64969
           dTDP-4-dehydrorhamnose reductase (EC 1.1.1.133) -
           Escherichia coli (strain K-12)
           >gi|1736730|dbj|BAA15882.1| (D90841)
           dTDP-4-dehydrorhamnose reductase (EC 1.1.1.133)
           (dTDP-4-keto-L- rhamnose reductase)
           (dTDP-6-deoxy-L-mannose dehydrogenase) (dTDP-L- rhamnose
           synthetase). [Escherichia coli]
           >gi|1736743|dbj|BAA15894.1| (D90842)
           dTDP-4-dehydrorhamnose reductase (EC 1.1.1.133)
           (dTDP-4-keto-L- rhamnose reductase)
           (dTDP-6-deoxy-L-mannose dehydrogenase) (dTDP-L- rhamnose
           synthetase). [Escherichia coli]
           >gi|1788352|gb|AAC75101.1| (AE000294)
           dTDP-6-deoxy-L-mannose-dehydrogenase [Escherichia coli
           K12] >gi|2665490|gb|AAB88399.1| (U09876)
           dTDP-6-deoxy-L-mannose-dehydrogenase [Escherichia coli]
           Length = 299
           
 Score =  142 bits (355), Expect = 4e-33
 Identities = 93/298 (31%), Positives = 147/298 (49%), Gaps = 25/298 (8%)

Query: 1   MRVAVIGANGQLGTDLVEVFGEEAIPLTRKDLDVTDFES--------LKILKELKPEVII 52
           M + + G  GQ+G +L          L   D+  TD+           + ++ ++P++I+
Sbjct: 1   MNILLFGKTGQVGWELQRALAPLG-NLIAFDVHSTDYCGDFSNPEGVAETVRSIRPDIIV 59

Query: 53  NTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEE 112
           N AA+  VD AE  PE A  +NA     +A+ ANE+GA  ++ STDYVF G    P+ E 
Sbjct: 60  NAAAHTAVDKAESEPEFAQLINATSVEAIAKAANEVGAWVIHYSTDYVFPGNGDMPWLET 119

Query: 113 DIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGE 172
           D   P+NVYG +K  GE   + Y  K+ I R + +Y      GKG NF + +++ A + E
Sbjct: 120 DATAPLNVYGETKLAGEKALQEYCAKHLIFRTSWVYA-----GKGNNFAKTMLRLAKERE 174

Query: 173 ELRIVNDQFMSPT----YTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFE-- 226
           EL ++NDQF +PT         A  +R  L      G+YH+V  G  +WY++   +FE  
Sbjct: 175 ELAVINDQFGAPTGAELLADCTAHAIRVALNKPDVAGLYHLVASGTTTWYDYAALVFEEA 234

Query: 227 -ILGWDVRVKPIN---SSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEALGEYLKE 279
              G  + +  +N   ++     A+RP  S L  EK ++   L +  W+  +   L E
Sbjct: 235 RKAGIPLALNKLNAVPTTAYPTPARRPHNSRLNTEKFQQNFALVLPDWQVGVKRMLNE 292


>pir||B36864 OAC2 protein - Azorhizobium caulinodans >gi|296708|emb|CAA80331.1|
           (Z22611) OAC2 [Azorhizobium caulinodans]
           Length = 296
           
 Score =  141 bits (353), Expect = 7e-33
 Identities = 96/274 (35%), Positives = 142/274 (51%), Gaps = 20/274 (7%)

Query: 1   MRVAVIGANGQLGTDLVEVFGEEAIPLT---RKDLDVTDFESL-KILKELKPEVIINTAA 56
           MRV ++GA+GQLG +L  +  E  + L    R   D+TD  ++ K L+  KP+V++N AA
Sbjct: 1   MRVLLLGADGQLGRELTALAVERGLALAALNRAATDITDPVAVAKALEAHKPDVVVNAAA 60

Query: 57  YVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPN 116
           Y  VD AE  P+ A KVNA+    +A      G   +++STDYVFDG K   Y E D   
Sbjct: 61  YTAVDKAESEPDLAAKVNAVAPGLIAERCASAGVPLIHVSTDYVFDGTKTGAYVESDPLA 120

Query: 117 PINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRI 176
           P+ VYG +K  GE   R   +K+ I+R A +YG       G NF++ +++ A   + L I
Sbjct: 121 PLGVYGRTKAAGEAAIRAAGEKHLILRTAWVYGI-----YGNNFLKTMLRLAKDRDRLTI 175

Query: 177 VNDQFMSPTYTKDVARTLRELLRLRPS------FGVYHMVNEGYCSWYEFTRAIFEILGW 230
           V DQ   PT T+D+A  +  L    P+      +G YH+   G  +W+ F +AI +    
Sbjct: 176 VADQRGCPTATRDIAEGI--LAAAAPAVAGSARWGTYHLGGTGVTTWHGFAQAIIDRAAT 233

Query: 231 DV---RVKPINSSELKRLAKRPKFSALKNEKLEK 261
                 V  I ++E    A+RP  S L +   E+
Sbjct: 234 YTGRSEVAAITTAEYPTPARRPANSELDSSLFER 267


>dbj|BAA19635.1| (AB002668) dTDP-4-rhamnose reductase [Actinobacillus
           actinomycetemcomitans]
           Length = 292
           
 Score =  141 bits (353), Expect = 7e-33
 Identities = 91/284 (32%), Positives = 147/284 (51%), Gaps = 20/284 (7%)

Query: 5   VIGANGQLGTDLVEVFG--EEAIPLTRKDLDVTDFESLK-ILKELKPEVIINTAAYVRVD 61
           + GANGQ+G  L +      E + +   +LD+T+  ++K  ++  +P+V+IN AA+  VD
Sbjct: 6   ITGANGQVGYCLTQQLQGKHEILAVDHDELDITNQNAVKKTVENFRPDVVINAAAHTAVD 65

Query: 62  DAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNPINVY 121
            AE   E +  +N  G   +A  A  +GA  ++ISTDYVFDG +   Y E D  +P  +Y
Sbjct: 66  RAETEIELSEAINVKGPQYLAETAKSVGAAILHISTDYVFDGRRAGKYKETDAVDPQGIY 125

Query: 122 GASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIVNDQF 181
           G +K  GE      + K+ ++R A ++ +      G NFV+ +++ A   + L +V DQ 
Sbjct: 126 GKTKLAGEQAVVEANDKFIVLRTAWVFCE-----HGSNFVKTMLRLAKTRDTLGVVADQI 180

Query: 182 MSPTYTKDVARTLRELLRL-----RPSFGVYHMVNEGYCSWYEFTRAIFE------ILGW 230
             PTY  D+A  L ++           +G+YH   E Y SW +F RAIF+      +L  
Sbjct: 181 GGPTYAGDIAAALIQIAEKIIAGESVEYGIYHFTGEPYVSWCDFARAIFDEAVSQNMLEK 240

Query: 231 DVRVKPINSSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEAL 273
              V  I +++    AKRP  S L   K+++  G++   W+ AL
Sbjct: 241 APLVNAIITADYPTPAKRPANSCLDLTKIQQAFGIQPSDWQRAL 284


>dbj|BAA94404.1| (AB041266) dTDP-6-deoxy-L-lyxo-4-hexulose redactase [Actinobacillus
           actinomycetemcomitans]
           Length = 292
           
 Score =  141 bits (352), Expect = 9e-33
 Identities = 90/284 (31%), Positives = 145/284 (50%), Gaps = 20/284 (7%)

Query: 5   VIGANGQLGTDLVEVFG--EEAIPLTRKDLDVTDFESLK-ILKELKPEVIINTAAYVRVD 61
           + GANGQ+G  L +      E + +   +LD+T+  ++K  ++  +P+V+IN AA+  VD
Sbjct: 6   ITGANGQVGYCLTQQLQGRHEILAVDHDELDITNQSAVKKTVENFRPDVVINAAAHTAVD 65

Query: 62  DAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNPINVY 121
            AE   E +  +N  G   +A  A  + A  ++ISTDYVFDG     Y E D  +P  +Y
Sbjct: 66  RAETEVERSEAINVKGPQYLAETAKSVDAAILHISTDYVFDGRSAGKYKETDAADPQGIY 125

Query: 122 GASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIVNDQF 181
           G +K  GE      + K+ ++R A ++ +      G NFV+ +++ A   + L +V DQ 
Sbjct: 126 GKTKLAGEQAVVEANDKFIVLRTAWVFCE-----HGNNFVKTMLRLAKTRDTLGVVADQI 180

Query: 182 MSPTYTKDVARTLRELLRL-----RPSFGVYHMVNEGYCSWYEFTRAIFE------ILGW 230
             PTY  D+A  L ++           +G+YH   E Y SW +F RAIF+      +L  
Sbjct: 181 GGPTYAGDIAAALIQIAEKIIAGESVEYGIYHFTGEPYVSWCDFARAIFDEAVSQNMLEK 240

Query: 231 DVRVKPINSSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEAL 273
              V  I +++    AKRP  S L   K+++  G++   W+ AL
Sbjct: 241 APLVNAITTADYPTPAKRPANSCLDLTKIQQAFGIQPSDWQRAL 284


>pir||C70978 probable rmlD protein - Mycobacterium tuberculosis (strain H37RV)
           >gi|1877321|emb|CAB07093.1| (Z92771) rmlD [Mycobacterium
           tuberculosis]
           Length = 304
           
 Score =  139 bits (347), Expect = 3e-32
 Identities = 101/286 (35%), Positives = 145/286 (50%), Gaps = 16/286 (5%)

Query: 2   RVAVIGANGQLGTDLVEVF---GEEAIPLTRKDLDVTDFESL-KILKELKPEVIINTAAY 57
           R+ + GA GQLG+ L       G + + LT    D+TD  +  +I++    +V+IN AAY
Sbjct: 7   RLVITGAGGQLGSHLTAQAAREGRDMLALTSSQWDITDPAAAERIIRH--GDVVINCAAY 64

Query: 58  VRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFD----GAKGEPYTEED 113
             VD AE     A+ VNA G  ++AR    +GA  +++STDYVFD    GA+  PY   D
Sbjct: 65  TDVDGAESNEAVAYAVNATGPQHLARACARVGARLIHVSTDYVFDGDFGGAEPRPYEPTD 124

Query: 114 IPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEE 173
              P  VY  SK  GE        +  ++R A +Y      G G +FV  + + A     
Sbjct: 125 ETAPQGVYARSKLAGEQAVLAAFPEAAVVRTAWVY----TGGTGKDFVAVMRRLAAGHGR 180

Query: 174 LRIVNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFEILGWD-V 232
           + +V+DQ  SPTY  D+A  L  L        V H  NEG  S +   RA+FE  G D  
Sbjct: 181 VDVVDDQTGSPTYVADLAEALLALADAGVRGRVLHAANEGVVSRFGQARAVFEECGADPQ 240

Query: 233 RVKPINSSELKRLAKRPKFSALKNEKLEKIGL-KMKHWKEALGEYL 277
           RV+P++S++  R A R  +SAL + +    GL  ++HW+ AL   L
Sbjct: 241 RVRPVSSAQFPRPAPRSSYSALSSRQWALAGLTPLRHWRSALATAL 286


>gb|AAA53680.1| (L14842) dTDP-6-deoxy-D-glucose-3,5 epimerase [Shigella flexneri]
           Length = 299
           
 Score =  137 bits (342), Expect = 1e-31
 Identities = 91/298 (30%), Positives = 151/298 (50%), Gaps = 25/298 (8%)

Query: 1   MRVAVIGANGQLGTDLVEVFGEEAIPLTRKDLDVTDFES--------LKILKELKPEVII 52
           M + + G  GQ+G +L          L   D+  TD+           + +K+++P+VI+
Sbjct: 1   MNILLFGKTGQVGWELQRALAPLG-NLIALDVHSTDYCGDFSNPEGVAETVKKIRPDVIV 59

Query: 53  NTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEE 112
           N AA+  VD AE  P  A  +NA     +A+ ANE+GA  ++ STDYVF G    P+ E 
Sbjct: 60  NAAAHTAVDKAESEPNFAQLLNATCVEAIAKAANEVGAWVIHYSTDYVFPGNGDTPWLET 119

Query: 113 DIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGE 172
           D   P+NVYG +K  GE   + +  K+ I R + +Y      GKG NF + +++ A + E
Sbjct: 120 DATAPLNVYGETKLAGEKALQEHCAKHLIFRTSWVYA-----GKGNNFAKTMLRLAKERE 174

Query: 173 ELRIVNDQFMSPTYTKDVARTLRELLRLRPS----FGVYHMVNEGYCSWYEFTRAIFE-- 226
           EL ++NDQF +PT  + +A      +R+  +     G+YH+V  G  +W+++   +FE  
Sbjct: 175 ELAVINDQFGAPTGAELLADCTAHAIRVAANKPEVAGLYHLVAGGTTTWHDYAALVFEEA 234

Query: 227 -ILGWDVRVKPIN---SSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEALGEYLKE 279
              G ++ +  +N   ++     A+RP  S L  EK ++   L +  W+  +   L E
Sbjct: 235 RRAGINLALNKLNAVPTTAYPTPARRPHNSRLNTEKFQQNFALVLPDWQVGVKRMLNE 292


>gb|AAF59936.1| (AF237895) 4-ketoreductase [Streptomyces antibioticus]
           Length = 294
           
 Score =  137 bits (341), Expect = 2e-31
 Identities = 94/281 (33%), Positives = 138/281 (48%), Gaps = 11/281 (3%)

Query: 1   MRVAVIGANGQLGTDLVEVFGE---EAIPLTRKDLDVT-DFESLKILKELKPEVIINTAA 56
           MR  + GA G LG +LV    E   +   L    LDVT  F     L E +P +++N AA
Sbjct: 1   MRWLITGAAGMLGRELVRRLAENEEDVAALGHDHLDVTRPFAVRAALAEHRPGIVVNCAA 60

Query: 57  YVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPN 116
           Y  VDDAE     A  +NA     +A      GA  V++STDYVF G    PY E+    
Sbjct: 61  YTAVDDAETDEAAAALLNAEAPRLLAEACAPHGARLVHLSTDYVFPGDARTPYAEDHPTA 120

Query: 117 PINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRI 176
           P + YG +K  GE           ++R A LYG+ G      +FV  +I++  +G  + +
Sbjct: 121 PRSAYGRTKRDGEQAVLTALPTATVLRTAWLYGRTGR-----SFVRTMIEREARGGAIDV 175

Query: 177 VNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFEILGWDV-RVK 235
           V DQ   PT+T D+A  +  + R     G+ H  N G  +WY+  + +F +L  D  RV+
Sbjct: 176 VADQCGQPTWTGDLADRIIAVGRHPGVHGILHATNAGSATWYDLAQEVFRLLDADPGRVR 235

Query: 236 PINSSELKRLAKRPKFSALKNEKLEKIGL-KMKHWKEALGE 275
           P   +  +R A RP +S L +++    GL  ++ W+ AL E
Sbjct: 236 PTTGAAFRRPAPRPAYSVLGHDRWRGTGLAPLRDWRSALRE 276


>gb|AAG09531.1|AF279623_2 (AF279623) dTDP-6-deoxy-L-mannose-dehydrogenase [Salmonella
           enterica]
           Length = 299
           
 Score =  137 bits (341), Expect = 2e-31
 Identities = 96/298 (32%), Positives = 152/298 (50%), Gaps = 25/298 (8%)

Query: 1   MRVAVIGANGQLGTDL----VEVFGEEAIPLTRKDLDVTDFESLK----ILKELKPEVII 52
           M + + G  GQ+G +L      V    A+ +  K+    DF + K     +++L+P+VI+
Sbjct: 1   MNILLFGKTGQVGWELQRSLAPVGNLIALDVHSKEF-CGDFSNPKGVAETVRKLRPDVIV 59

Query: 53  NTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEE 112
           N AA+  VD AE  PE A  +NA     +A+ ANE GA  V+ STDYVF G    P+ E 
Sbjct: 60  NAAAHTAVDKAESEPELAQLLNATSVEAIAKAANETGAWVVHYSTDYVFPGTGDIPWQET 119

Query: 113 DIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGE 172
           DI +P+NVYG +K  GE   ++   K+ I R + +Y      GKG NF + +++ A + +
Sbjct: 120 DITSPLNVYGKTKLAGEKALQDNGPKHLIFRTSWVYA-----GKGNNFAKTMLRLAKERQ 174

Query: 173 ELRIVNDQFMSPT----YTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFE-- 226
            L ++NDQ+ +PT         A  +R  L+     G+YH+V  G  +W+++   IF+  
Sbjct: 175 TLSVINDQYGAPTGAELLADCTAHAIRVALKKPEVAGLYHLVAGGTTTWHDYAALIFDEA 234

Query: 227 -ILGWDVRVKPIN---SSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEALGEYLKE 279
              G  + +  +N   +S     A RP  S L  EK ++  GL +  W+  +   L E
Sbjct: 235 RKAGITLALTELNAVPTSAYPTPASRPGNSRLNTEKFQRNFGLILPQWELGVKRMLTE 292


>gb|AAG09514.1|AF279619_2 (AF279619) dTDP-6-deoxy-L-mannose-dehydrogenase [Salmonella
           enterica]
           Length = 299
           
 Score =  136 bits (340), Expect = 2e-31
 Identities = 92/297 (30%), Positives = 153/297 (50%), Gaps = 23/297 (7%)

Query: 1   MRVAVIGANGQLGTDLVEVFGEE----AIPLTRKDL--DVTDFESL-KILKELKPEVIIN 53
           M + + G NGQ+G +L           A+ +  KD   D ++ E + + ++ ++P+VI+N
Sbjct: 1   MNILLFGKNGQVGWELQRSLAPLGKIIALDVHSKDYCGDFSNPEGVAETIRRIRPDVIVN 60

Query: 54  TAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEED 113
            AA+  VD AE   E A  +NA     +A+ A+E GA  V+ STDYVF G    P+ E+D
Sbjct: 61  AAAHTAVDKAESEVEFATLLNARSVEAIAKAASETGAWVVHYSTDYVFPGTGETPWCEDD 120

Query: 114 IPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEE 173
              P+NVYG +K  GE   ++   ++ I R + +Y      GKG NF + +++ A + EE
Sbjct: 121 ATAPLNVYGETKLTGEKALQDNCARHLIFRTSWVYA-----GKGNNFAKTMLRFAKEREE 175

Query: 174 LRIVNDQFMSPT----YTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFE--- 226
           + ++NDQ+ +PT         A  +R  L+     G+YH+V  G  +WYE+   +F+   
Sbjct: 176 MSVINDQYGAPTGAELLADCTAHAIRVALKQPEVAGLYHLVAGGTTTWYEYAALVFDEAR 235

Query: 227 ILGWDVRVKPIN---SSELKRLAKRPKFSALKNEKLE-KIGLKMKHWKEALGEYLKE 279
             G ++ +  +N   +S     A+RP  S L  +K + K  L +  W+  +   L E
Sbjct: 236 KAGIELAINKLNAVPTSAYPTPARRPNNSRLNTDKFQKKFDLVLPEWEIGVRRMLAE 292


>pir||C55213 rfbC protein - Shigella flexneri (strain 2a)
           Length = 299
           
 Score =  136 bits (339), Expect = 3e-31
 Identities = 91/298 (30%), Positives = 151/298 (50%), Gaps = 25/298 (8%)

Query: 1   MRVAVIGANGQLGTDLVEVFGEEAIPLTRKDLDVTDFES--------LKILKELKPEVII 52
           M + + G  GQ+G +L          L   D+  TD+           + +K+++P+VI+
Sbjct: 1   MNILLFGKTGQVGWELQRALAPLG-NLIALDVHSTDYCGDFSNPEGVAETVKKIRPDVIV 59

Query: 53  NTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEE 112
           N AA+  VD AE  P  A  +NA     +A+ ANE+GA  ++ STDYVF G    P+ E 
Sbjct: 60  NAAAHTAVDKAESEPNFAQLLNATCVEAIAKAANEVGAWVIHYSTDYVFPGNGDTPWLET 119

Query: 113 DIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGE 172
           D   P+NVYG +K  GE   + +  K+ I R + +Y      GKG NF + +++ A + E
Sbjct: 120 DATAPLNVYGETKLAGEKALQEHCAKHLIFRTSWVYA-----GKGNNFAKTMLRLAKERE 174

Query: 173 ELRIVNDQFMSPTYTKDVARTLRELLRLRPS----FGVYHMVNEGYCSWYEFTRAIFE-- 226
           EL ++NDQF +PT  + +A      +R+  +     G+YH+V  G  +W+++   +FE  
Sbjct: 175 ELAVINDQFGAPTGAELLADCTAAHIRVAANKPEVAGLYHLVAGGTTTWHDYAALVFEEA 234

Query: 227 -ILGWDVRVKPIN---SSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEALGEYLKE 279
              G ++ +  +N   ++     A+RP  S L  EK ++   L +  W+  +   L E
Sbjct: 235 RRAGINLALNKLNAVPTTAYPTPARRPHNSRLNTEKFQQNFALVLPDWQVGVKRMLNE 292


>gb|AAG09527.1|AF279622_2 (AF279622) dTDP-6-deoxy-L-mannose-dehydrogenase [Salmonella
           enterica]
           Length = 299
           
 Score =  136 bits (339), Expect = 3e-31
 Identities = 95/298 (31%), Positives = 152/298 (50%), Gaps = 25/298 (8%)

Query: 1   MRVAVIGANGQLGTDL----VEVFGEEAIPLTRKDLDVTDFESLK----ILKELKPEVII 52
           M + + G  GQ+G +L      V    A+ +  K+    DF + K     +++L+P+VI+
Sbjct: 1   MNILLFGKTGQVGWELQRSLAPVGNLIALDVHSKEF-CGDFSNPKGVAETVRKLRPDVIV 59

Query: 53  NTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEE 112
           N AA+  VD AE  PE A  +NA     +A+ ANE GA  V+ STDYVF G    P+ E 
Sbjct: 60  NAAAHTAVDKAESEPELAQLLNATSVEAIAKAANETGAWVVHYSTDYVFPGTGDIPWQET 119

Query: 113 DIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGE 172
           DI +P+NVYG +K  GE   ++   K+ I R + +Y      GKG NF + +++ A + +
Sbjct: 120 DITSPLNVYGKTKLAGEKALQDSCPKHLIFRTSWVYA-----GKGNNFAKTMLRLAKERQ 174

Query: 173 ELRIVNDQFMSPT----YTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFE-- 226
            L ++NDQ+ +PT         A  +R  L+     G+YH+V  G  +W+++   +F+  
Sbjct: 175 TLSVINDQYGAPTGAELLADCTAHAIRVALKKPEVAGLYHLVAGGTTTWHDYAALVFDEA 234

Query: 227 -ILGWDVRVKPIN---SSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEALGEYLKE 279
              G  + +  +N   +S     A RP  S L  EK ++  GL +  W+  +   L E
Sbjct: 235 RKAGITLALTELNAVPTSAYPTPASRPGNSRLNTEKFQRNFGLILPQWELGVKRMLTE 292


>gb|AAG09510.1|AF279618_2 (AF279618) dTDP-6-deoxy-L-mannose-dehydrogenase [Salmonella
           enterica]
           Length = 299
           
 Score =  136 bits (338), Expect = 4e-31
 Identities = 95/298 (31%), Positives = 151/298 (49%), Gaps = 25/298 (8%)

Query: 1   MRVAVIGANGQLGTDL----VEVFGEEAIPLTRKDLDVTDFESLK----ILKELKPEVII 52
           M + + G  GQ+G +L      V    A+ +  K+    DF + K     +++L+P+VI+
Sbjct: 1   MNILLFGKTGQVGWELQRSLAPVGNLIALDVHSKEF-CGDFSNPKGVAETVRKLRPDVIV 59

Query: 53  NTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEE 112
           N AA+  VD AE  PE A  +NA     +A+ ANEIGA  V+ STDYVF G    P+ E 
Sbjct: 60  NAAAHTAVDKAESEPELAQLLNATSVEAIAKAANEIGAWVVHYSTDYVFPGTGDIPWQET 119

Query: 113 DIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGE 172
           D  +P+NVYG +K  GE   ++   K+ I R + +Y      GKG NF + +++ A + +
Sbjct: 120 DATSPLNVYGKTKLAGEKALQDNCPKHLIFRTSWVYA-----GKGNNFAKTMLRLAKERQ 174

Query: 173 ELRIVNDQFMSPT----YTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFE-- 226
            L ++NDQ+ +PT         A  +R  L+     G+YH+V  G  +W+++   +F+  
Sbjct: 175 TLSVINDQYGAPTGAELLADCTAHAIRVALKKPEVAGLYHLVAGGTTTWHDYAALVFDEA 234

Query: 227 -ILGWDVRVKPIN---SSELKRLAKRPKFSALKNEKLE-KIGLKMKHWKEALGEYLKE 279
              G  + +  +N   +S     A RP  S L  EK +   GL +  W+  +   L E
Sbjct: 235 RKAGLTLALTELNAVPTSAYPTPASRPGNSRLNTEKFQSNFGLILPQWELGVKRMLTE 292


>gb|AAG09523.1|AF279621_2 (AF279621) dTDP-6-deoxy-L-mannose-dehydrogenase [Salmonella
           enterica]
           Length = 299
           
 Score =  136 bits (338), Expect = 4e-31
 Identities = 95/298 (31%), Positives = 151/298 (49%), Gaps = 25/298 (8%)

Query: 1   MRVAVIGANGQLGTDL----VEVFGEEAIPLTRKDLDVTDFESLK----ILKELKPEVII 52
           M + + G  GQ+G +L      V    A+ +  K+    DF + K     +++L+P+VI+
Sbjct: 1   MNILLFGKTGQVGWELQRSLAPVGNLIALDVHSKEF-CGDFSNPKGVAETVRKLRPDVIV 59

Query: 53  NTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEE 112
           N AA+  VD AE  PE A  +NA     +A+ ANE GA  V+ STDYVF G    P+ E 
Sbjct: 60  NAAAHTAVDKAESEPELAQLLNATSVEAIAKAANETGAWVVHYSTDYVFPGTGDIPWQET 119

Query: 113 DIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGE 172
           DI +P+NVYG +K  GE   ++   K+ I R + +Y      GKG NF + +++ A + +
Sbjct: 120 DITSPLNVYGKTKLAGEKALQDNCPKHLIFRTSWVYA-----GKGNNFAKTMLRLAKERQ 174

Query: 173 ELRIVNDQFMSPT----YTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFE-- 226
            L ++NDQ+ +PT         A  +R  L      G+YH+V  G  +W+++   +F+  
Sbjct: 175 TLSVINDQYGAPTGAELLADCTAHAIRVALNKPEVAGLYHLVAGGTTTWHDYAALVFDEA 234

Query: 227 -ILGWDVRVKPIN---SSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEALGEYLKE 279
              G  + +  +N   +S     A RP  S L  EK ++  GL +  W+  +   L E
Sbjct: 235 RKAGLTLALTELNAVPTSAYPTPASRPGNSRLNTEKFQRNFGLILPQWELGVKRMLTE 292


>gb|AAG09503.1|AF279616_2 (AF279616) dTDP-6-deoxy-L-mannose-dehydrogenase [Salmonella
           enterica]
           Length = 299
           
 Score =  135 bits (336), Expect = 7e-31
 Identities = 94/298 (31%), Positives = 151/298 (50%), Gaps = 25/298 (8%)

Query: 1   MRVAVIGANGQLGTDL----VEVFGEEAIPLTRKDLDVTDFESLK----ILKELKPEVII 52
           M + + G  GQ+G +L      V    A+ +  K+    DF + K     +++L+P+VI+
Sbjct: 1   MNILLFGKTGQVGWELQRSLAPVGNLTALDVHSKEF-CGDFSNPKGVAETVRKLRPDVIV 59

Query: 53  NTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEE 112
           N AA+  VD AE  PE A  +NA     +A+ ANE GA  V+ STDYVF G    P+ E 
Sbjct: 60  NAAAHTAVDKAESEPELAQLLNATSVEAIAKAANETGAWVVHYSTDYVFPGTGDIPWQET 119

Query: 113 DIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGE 172
           D  +P+NVYG +K  GE   ++   K+ I R + +Y      GKG NF + +++ A + +
Sbjct: 120 DATSPLNVYGKTKLAGEKALQDNCPKHLIFRTSWVYA-----GKGNNFAKTMLRLAKERQ 174

Query: 173 ELRIVNDQFMSPT----YTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFE-- 226
            L ++NDQ+ +PT         A  +R  L+     G+YH+V  G  +W+++   +F+  
Sbjct: 175 TLSVINDQYGAPTGAELLADCTAHAIRVALKKPEVAGLYHLVAGGTTTWHDYAALVFDEA 234

Query: 227 -ILGWDVRVKPIN---SSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEALGEYLKE 279
              G  + +  +N   +S     A RP  S L  EK ++  GL +  W+  +   L E
Sbjct: 235 RKAGITLALTELNAVPTSAYPTPASRPGNSRLNTEKFQRNFGLILPQWELGVKRMLTE 292


>gb|AAC44075.1| (U51197) dTDP-6-deoxy-L-mannose-dehydrogenase [Sphingomonas sp.
           S88]
           Length = 288
           
 Score =  134 bits (335), Expect = 9e-31
 Identities = 92/286 (32%), Positives = 150/286 (52%), Gaps = 16/286 (5%)

Query: 1   MRVAVIGANGQLGTDLVE-VFGEEAIPLTRKDLDVTDFESLKI-LKELKPEVIINTAAYV 58
           MR+ V G +GQ+   L E   G E I  +  + D++  E+++  + +++PE+I++ AAY 
Sbjct: 1   MRILVTGHDGQVAQALGEQAEGHELIFTSYPEFDLSKPETIEAAVAKIQPELIVSAAAYT 60

Query: 59  RVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNPI 118
            VD +E  PE A  +N  G   +AR   +IGA  +++STDYVFDG+   P+ E+D   P+
Sbjct: 61  AVDKSESEPELAMAINGDGPGVLARAGAKIGAPIIHLSTDYVFDGSLDRPWREDDPTGPL 120

Query: 119 NVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIVN 178
            VYGA+K  GE   +       +IR+A +Y        G NFV+ +++ A   + L +V 
Sbjct: 121 GVYGATKLAGEQAVQASGATNAVIRLAWVYSPF-----GNNFVKTMLRLAETRDTLNVVE 175

Query: 179 DQFMSPTYTKDVARTLRELL----RLRPSFGVYHMVNEGYCSWYEFTRAIF----EILGW 230
           DQ   P+   D+A  + +++    +   + G+YH    G  +W +F RAIF    +  G 
Sbjct: 176 DQQGCPSSALDIATAILKVVGHWQQNGATSGLYHFTGSGETNWADFARAIFAESAKHGGP 235

Query: 231 DVRVKPINSSELKRLAKRPKFSALKNEKL-EKIGLKMKHWKEALGE 275
              V  I +S     AKRP  S L  +K  E  G +   W++++ E
Sbjct: 236 TAEVTGIPTSGYPTPAKRPANSRLNCDKFAETFGYRAPAWQDSVAE 281


>gb|AAG09535.1|AF279624_2 (AF279624) dTDP-6-deoxy-L-mannose-dehydrogenase [Salmonella
           enterica]
           Length = 299
           
 Score =  134 bits (335), Expect = 9e-31
 Identities = 95/298 (31%), Positives = 151/298 (49%), Gaps = 25/298 (8%)

Query: 1   MRVAVIGANGQLGTDL----VEVFGEEAIPLTRKDLDVTDFESLK----ILKELKPEVII 52
           M + + G  GQ+G +L      V    A+ +  K+    DF + K     +++L+P+VI+
Sbjct: 1   MNILLFGKTGQVGWELQRSLAPVGNLIALDVHSKEF-CGDFSNPKGVAETVRKLRPDVIV 59

Query: 53  NTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEE 112
           N AA+  VD AE  PE A  +NA     +A+ ANE GA  V+ STDYVF G    P+ E 
Sbjct: 60  NAAAHTAVDKAESEPELAQLLNATSVEAIAKAANETGAWVVHYSTDYVFPGTGDIPWQET 119

Query: 113 DIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGE 172
           DI +P+NVYG +K  GE   +    K+ I R + +Y      GKG NF + +++ A + +
Sbjct: 120 DITSPLNVYGKTKLAGEKALQCNCPKHLIFRTSWVYA-----GKGNNFAKTMLRLAKERQ 174

Query: 173 ELRIVNDQFMSPT----YTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFE-- 226
            L ++NDQ+ +PT         A  +R  L+     G+YH+V  G  +W+++   +F+  
Sbjct: 175 TLSVINDQYGAPTGAELLADCTAHAIRVALKKPEVAGLYHLVAGGTTTWHDYAALVFDEA 234

Query: 227 -ILGWDVRVKPIN---SSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEALGEYLKE 279
              G  + +  +N   +S     A RP  S L  EK ++  GL +  W+  +   L E
Sbjct: 235 RKAGITLALTELNAVPTSAYPTPASRPGNSRLNTEKFQRNFGLILPQWELGVKRMLTE 292


>gb|AAG09499.1|AF279615_2 (AF279615) dTDP-6-deoxy-L-mannose-dehydrogenase [Salmonella
           enterica]
           Length = 299
           
 Score =  134 bits (334), Expect = 1e-30
 Identities = 94/298 (31%), Positives = 151/298 (50%), Gaps = 25/298 (8%)

Query: 1   MRVAVIGANGQLGTDL----VEVFGEEAIPLTRKDLDVTDFESLK----ILKELKPEVII 52
           M + + G  GQ+G +L      V    A+ +  K+    DF + K     +++L+P+VI+
Sbjct: 1   MNILLFGKTGQVGWELQRSLAPVGNLIALDVHSKEF-CGDFSNPKGVAETVRKLRPDVIV 59

Query: 53  NTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEE 112
           N AA+  VD AE  PE A  +NA     +A+ ANE GA  V+ STDYVF G    P+ E 
Sbjct: 60  NAAAHTAVDKAESEPELAQLLNATSVEAIAKAANETGAWVVHYSTDYVFPGTGDIPWQET 119

Query: 113 DIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGE 172
           D  +P+NVYG +K  GE   ++   K+ I R + +Y      GKG NF + +++ A + +
Sbjct: 120 DATSPLNVYGKTKLAGEKALQDNCPKHLIFRTSWVYA-----GKGNNFAKTMLRLAKERQ 174

Query: 173 ELRIVNDQFMSPT----YTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFE-- 226
            L ++NDQ+ +PT         A  +R +L      G+YH+V  G  +W+++   +F+  
Sbjct: 175 TLSVINDQYGAPTGAELLADCTAHAIRVVLNKPEVAGLYHLVAGGTTTWHDYAALVFDEA 234

Query: 227 -ILGWDVRVKPIN---SSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEALGEYLKE 279
              G  + +  +N   +S     A RP  S L  EK ++  GL +  W+  +   L E
Sbjct: 235 RKAGITLALTELNAVPTSAYPTPASRPGNSRLNTEKFQRNFGLILPQWELGVKRMLTE 292


>gb|AAG09518.1|AF279620_2 (AF279620) dTDP-6-deoxy-L-mannose-dehydrogenase [Salmonella
           enterica]
           Length = 299
           
 Score =  134 bits (333), Expect = 2e-30
 Identities = 94/298 (31%), Positives = 151/298 (50%), Gaps = 25/298 (8%)

Query: 1   MRVAVIGANGQLGTDL----VEVFGEEAIPLTRKDLDVTDFESLK----ILKELKPEVII 52
           M + + G  GQ+G +L      V    A+ +  K+    DF + K     +++L+P+VI+
Sbjct: 1   MNILLFGKTGQVGWELQRSLAPVGNLIALDVHSKEF-CGDFSNPKGVAETVRKLRPDVIV 59

Query: 53  NTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEE 112
           N AA+  VD AE  PE A  +NA     +A+ ANE GA  V+ STDYVF G    P+ E 
Sbjct: 60  NAAAHTAVDKAESEPELAQLLNATSVEAIAKAANETGAWVVHYSTDYVFPGTGDIPWQET 119

Query: 113 DIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGE 172
           DI +P+NVYG +K  GE   ++   K+ I R + +Y      GKG NF + +++ A + +
Sbjct: 120 DITSPLNVYGKTKLAGEKALQDNCPKHLIFRTSWVYA-----GKGNNFAKTMLRLAKERQ 174

Query: 173 ELRIVNDQFMSPT----YTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFE-- 226
            L ++NDQ+ +PT         A  +R  L+     G+YH+V  G  +W+++   +F+  
Sbjct: 175 TLSVINDQYGAPTGAELLADCTAHAIRVALKKPEVAGLYHLVAGGTTTWHDYAALVFDEA 234

Query: 227 -ILGWDVRVKPIN---SSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEALGEYLKE 279
              G  + +  +N   +S     A RP  S L  EK ++   L +  W+  +   L E
Sbjct: 235 RKAGITLALTELNAVPTSAYPTSANRPGNSRLNTEKFQRNFDLILPQWELGVKRMLTE 292


>pir||T00085 dTDP-4-dehydrorhamnose reductase (EC 1.1.1.133) - Streptococcus
           mutans (fragment) >gi|3399703|dbj|BAA32088.1| (AB010970)
           dTDP-4-keto-L-rhamonose reductase [Streptococcus mutans]
           Length = 219
           
 Score =  131 bits (326), Expect = 1e-29
 Identities = 77/213 (36%), Positives = 113/213 (52%), Gaps = 11/213 (5%)

Query: 71  FKVNAIGALNVARIANEIGAINVYISTDYVFDGAK--GEPYTEEDIPNPINVYGASKYIG 128
           + +N  G  N+A+   +  A  VYISTDYVFDG K  G+ +  +D P+P   YG +K +G
Sbjct: 10  YAINVTGTENIAKACEKYNATLVYISTDYVFDGEKPVGQEWEVDDKPDPKTEYGRTKRLG 69

Query: 129 EIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIVNDQFMSPTYTK 188
           E     Y K +YIIR A ++G  G      NFV  +   A     L +VNDQ   PT+T+
Sbjct: 70  EEAVEKYVKNFYIIRTAWVFGNYGK-----NFVFTMQHLAKSHNSLTVVNDQHGRPTWTR 124

Query: 189 DVARTLRELLRLRPSFGVYHMVNEGY--CSWYEFTRAIFEILGWDVRVKPINSSELKRLA 246
            +A  +  L   +  +G YH+ N+     +WY+F   I +    DV VKP++SS+    A
Sbjct: 125 TLAEFMTYLAENQKEYGYYHLSNDATEDTTWYDFALEILK--DTDVVVKPVDSSQFPAKA 182

Query: 247 KRPKFSALKNEKLEKIGLKMKHWKEALGEYLKE 279
           KRP  S +   K +  G  +  W+EAL E+ K+
Sbjct: 183 KRPLNSTMSLTKAKATGFVIPTWQEALQEFYKQ 215


>sp|P26392|RFBD_SALTY DTDP-4-DEHYDRORHAMNOSE REDUCTASE (DTDP-4-KETO-L-RHAMNOSE REDUCTASE)
           (DTDP-6-DEOXY-L-MANNOSE DEHYDROGENASE) (DTDP-L-RHAMNOSE
           SYNTHETASE) >gi|96839|pir||S15300 rfbA protein -
           Salmonella typhimurium >gi|47890|emb|CAA40116.1|
           (X56793) dTDP-6-deoxy-L-mannose dehydrogenase
           [Salmonella enterica]
           Length = 299
           
 Score =  131 bits (325), Expect = 1e-29
 Identities = 93/298 (31%), Positives = 149/298 (49%), Gaps = 25/298 (8%)

Query: 1   MRVAVIGANGQLGTDL----VEVFGEEAIPLTRKDLDVTDFESLK----ILKELKPEVII 52
           M + + G  GQ+G +L      V    A+ +  K+    DF + K     +++L+P+VI+
Sbjct: 1   MNILLFGKTGQVGWELQRSLAPVGNLIALDVHSKEF-CGDFSNPKGVAETVRKLRPDVIV 59

Query: 53  NTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEE 112
           N AA+  VD AE  PE A  +NA     +A+ ANE GA  V+ STDYVF G    P+ E 
Sbjct: 60  NAAAHTAVDKAESEPELAQLLNATSVEAIAKAANETGAWVVHYSTDYVFPGTGDIPWQET 119

Query: 113 DIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGE 172
           D  +P+NVYG +K  GE   ++   K+ I R + +Y      GKG NF + +++ A + +
Sbjct: 120 DATSPLNVYGKTKLAGEKALQDNCPKHLIFRTSWVYA-----GKGNNFAKTMLRLAKERQ 174

Query: 173 ELRIVNDQFMSPT----YTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFE-- 226
            L ++NDQ+ +PT         A  +R  L      G+YH+V  G  +W+++   +F+  
Sbjct: 175 TLSVINDQYGAPTGAELLADCTAHAIRVALNKPEVAGLYHLVAGGTTTWHDYAALVFDEA 234

Query: 227 -ILGWDVRVKPIN---SSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEALGEYLKE 279
              G  + +  +N   +S     A RP  S L  EK ++   L +  W+  +   L E
Sbjct: 235 RKAGITLALTELNAVPTSAYPTPASRPGNSRLNTEKFQRNFDLILPQWELGVKRMLTE 292


>gb|AAG09538.1|AF279625_2 (AF279625) dTDP-6-deoxy-L-mannose-dehydrogenase [Salmonella
           enterica]
           Length = 299
           
 Score =  129 bits (320), Expect = 5e-29
 Identities = 90/297 (30%), Positives = 146/297 (48%), Gaps = 23/297 (7%)

Query: 1   MRVAVIGANGQLGTDL---VEVFGEEAIPLTRKDLDVTDFESLK----ILKELKPEVIIN 53
           M + + G  GQ+G +L   +   G   +          DF + K     +++L+P+VI+N
Sbjct: 1   MNILLFGKTGQVGWELQRSLAPVGNLIVLDVHSKEFCGDFSNPKGVAETVRKLRPDVIVN 60

Query: 54  TAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEED 113
            AA+  VD AE  PE A  +NA     +A+ ANE G+  V+ STDYVF G    P+ E D
Sbjct: 61  AAAHTAVDKAESEPELAQLLNATSVEAIAKAANETGSWVVHYSTDYVFPGTGDIPWQETD 120

Query: 114 IPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEE 173
             +P+NVYG +K  GE   ++   K+ I R + +Y      GKG NF + +++ A + + 
Sbjct: 121 ATSPLNVYGKTKLAGEKALQDNCPKHLIFRTSWVYA-----GKGNNFAKTMLRLAKERQT 175

Query: 174 LRIVNDQFMSPT----YTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFE--- 226
           L ++NDQ+ +PT         A  +R  L      G+YH+V  G  +W+++   +F+   
Sbjct: 176 LSVINDQYGAPTGAELLADCTAHAIRVALNKPEVAGLYHLVAGGTTTWHDYAALVFDEAR 235

Query: 227 ILGWDVRVKPIN---SSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEALGEYLKE 279
             G  + +  +N   +S     A RP  S L  EK ++   L +  W+  +   L E
Sbjct: 236 KAGITLALTELNAVPTSAYPTSASRPGNSRLNTEKFQRNFDLILPQWELGVKRMLTE 292


>emb|CAB01952.1| (Z79692) ExpA10 [Sinorhizobium meliloti]
           Length = 275
           
 Score =  128 bits (319), Expect = 7e-29
 Identities = 88/261 (33%), Positives = 134/261 (50%), Gaps = 19/261 (7%)

Query: 23  EAIPLTRKDLDVTDFES-LKILKELKPEVIINTAAYVRVDDAELYPEEAFKVNAIGALNV 81
           E + + R  LD+T+  + L  ++  +P+++++ AAY  VD AE  PE AF VNA GA  V
Sbjct: 2   EVVTIGRPHLDLTEPATILPAIERCRPDLVVSAAAYTAVDQAESEPEAAFAVNAFGAGAV 61

Query: 82  ARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNPINVYGASKYIGEIFTRNYSKKYYI 141
           A  A  +    V+ISTDYVFDG+K   Y E D P P++VYGASK  GE      + ++ I
Sbjct: 62  AEAAACLEVPIVHISTDYVFDGSKPRSYAEGDTPAPLSVYGASKLAGESAVAEATPRHLI 121

Query: 142 IRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIVNDQFMSPTYTKDVARTLREL---- 197
           +R   +Y   G      NFV+ +++ A + E++ +V DQ  +P+   D+A  + ++    
Sbjct: 122 LRTGWVYSPFGK-----NFVKTILRLAEEREDIAVVADQRGNPSSAIDLADAILDISARL 176

Query: 198 --LRLRPSFGVYHMVNEGYCSWYEFTR---AIFEILG--WDVRVKPINSSELKRLAKRPK 250
              R   +FG+YH+   G  S  +F R   A     G  W   V+ I +      A RP 
Sbjct: 177 TKSRQDAAFGLYHLAGSGVVSRADFARHALAASRAAGGPW-AHVRDIATGGFPTPASRPA 235

Query: 251 FSALKNEKLE-KIGLKMKHWK 270
            S+L + K     G  M  W+
Sbjct: 236 NSSLSSAKFNATFGQAMPAWQ 256


>pir||G70346 spore coat polysaccharide biosynthesis protein SpsK - Aquifex
           aeolicus >gi|2983168|gb|AAC06769.1| (AE000694) spore
           coat polysaccharide biosynthesis protein SpsK [Aquifex
           aeolicus]
           Length = 137
           
 Score =  128 bits (319), Expect = 7e-29
 Identities = 59/129 (45%), Positives = 86/129 (65%), Gaps = 4/129 (3%)

Query: 149 GKAGARGKGGNFVEWVIKKANKGEELRIVNDQFMSPTYTKDVARTLRELLRLRPSFGVYH 208
           GKAGA  KGGNFV  +I+KA  GE LR+V+D +MSPTYT D A+ + ++L     +G+YH
Sbjct: 3   GKAGASSKGGNFVYTIIRKAKAGEPLRVVDDIYMSPTYTLDAAKEIWKILLENKPYGIYH 62

Query: 209 MVNEGYCSWYEFTRAIFEILGWDVRVKPINSSELKRLAKRPKFSALKNEKLEKIGLKMKH 268
           + N GYCSWYEF   I E  G    +KP+  +E K  A RP +S L +++    G+K+++
Sbjct: 63  VTNSGYCSWYEFAVKILEYSGLKTDIKPVRHTEFKTKANRPLWSPLASKR----GIKLRN 118

Query: 269 WKEALGEYL 277
           W+EAL +++
Sbjct: 119 WEEALKDFI 127


>pir||T51107 4-ketoreductase [validated] - Streptomyces antibioticus  (ATCC
           11891) >gi|5902171|gb|AAD55455.1| (AF055579)
           4-ketoreductase [Streptomyces antibioticus]
           Length = 295
           
 Score =  127 bits (317), Expect = 1e-28
 Identities = 93/284 (32%), Positives = 140/284 (48%), Gaps = 16/284 (5%)

Query: 1   MRVAVIGANGQLGTDLVEVFGE---EAIPLTRKDLDVTDFESLKI-LKELKPEVIINTAA 56
           MR  + GA G LG +LV    E   +   L    LDVT   +++  L E +P +++N AA
Sbjct: 1   MRWLITGAAGMLGRELVRRLAENEEDVAALGHDHLDVTRPSAVRAALAEHRPGIVVNCAA 60

Query: 57  YVRVDDAELYPEEAFKVNAIGALNVA---RIANEIGAINVYISTDYVFDGAKGEPYTEED 113
           Y  VDDAE     A  +NA     +A   R     G   V++STDYVF G    PY E+ 
Sbjct: 61  YTAVDDAETDEAAAALLNAEAPRLLAEGLRPHRRHGL--VHLSTDYVFPGDARTPYAEDH 118

Query: 114 IPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEE 173
              P + YG +K  GE           ++R A LYG+ G      +FV  +I++  +G  
Sbjct: 119 PTAPRSAYGRTKRDGEQAVLTALPTATVLRTAWLYGRTGR-----SFVRTMIEREARGGA 173

Query: 174 LRIVNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFEILGWDV- 232
           + +V DQ   PT+T D+A  +  + R     G+ H  N G  +WY+  + +F +L  D  
Sbjct: 174 IDVVADQRGQPTWTGDLADRIIAVGRHPGVHGILHATNAGSATWYDLAQEVFRLLDADPG 233

Query: 233 RVKPINSSELKRLAKRPKFSALKNEKLEKIGL-KMKHWKEALGE 275
           RV+P   +  +R A RP +S L +++    GL  ++ W+ AL E
Sbjct: 234 RVRPTTGAAFRRPAPRPAYSVLGHDRWRGTGLAPLRDWRSALRE 277


>pir||S23348 hypothetical protein 5.2 - Salmonella choleraesuis
           >gi|431939|emb|CAA43073.1| (X60665)
           dTDP-6-deoxy-L-mannose dehydrogenase [Salmonella
           enterica]
           Length = 248
           
 Score =  126 bits (314), Expect = 3e-28
 Identities = 81/246 (32%), Positives = 127/246 (50%), Gaps = 16/246 (6%)

Query: 45  ELKPEVIINTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGA 104
           +L+P+VI+N AA+  VD AE  PE A  +NA     +A+ ANE GA  V+ STDYVF G 
Sbjct: 1   KLRPDVIVNAAAHTAVDKAESEPELAQLLNATSVEAIAKAANETGAWVVHYSTDYVFPGT 60

Query: 105 KGEPYTEEDIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWV 164
              P+ E D  +P+NVYG +K  GE   ++   K+ I R + +Y      GKG NF + +
Sbjct: 61  GDIPWQETDATSPLNVYGKTKLAGEKALQDNCPKHLIFRTSWVYA-----GKGNNFAKTM 115

Query: 165 IKKANKGEELRIVNDQFMSPT----YTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEF 220
           ++ A + + L ++NDQ+ +PT         A  +R  L      G+YH+V  G  +W+++
Sbjct: 116 LRLAKERQTLSVINDQYGAPTGAELLADCTAHAIRVALNKPEVAGLYHLVAGGTTTWHDY 175

Query: 221 TRAIFE---ILGWDVRVKPIN---SSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEAL 273
              +F+     G  + +  +N   +S     A RP  S L  EK ++   L +  W+  +
Sbjct: 176 AALVFDEARKAGITLALTELNAVPTSAYPTPASRPGNSRLNTEKFQRNFDLILPQWELGV 235

Query: 274 GEYLKE 279
              L E
Sbjct: 236 KRMLTE 241


>sp|Q46769|RBD2_ECOLI DTDP-4-DEHYDRORHAMNOSE REDUCTASE (DTDP-4-KETO-L-RHAMNOSE REDUCTASE)
           (DTDP-6-DEOXY-L-MANNOSE DEHYDROGENASE) (DTDP-L-RHAMNOSE
           SYNTHETASE) >gi|7436795|pir||S78543
           dTDP-4-dehydrorhamnose reductase (EC 1.1.1.133) -
           Escherichia coli (strain VW187)
           >gi|799233|gb|AAC63613.1| (AF125322) RmlD [Escherichia
           coli]
           Length = 301
           
 Score =  123 bits (307), Expect = 2e-27
 Identities = 91/300 (30%), Positives = 150/300 (49%), Gaps = 27/300 (9%)

Query: 1   MRVAVIGANGQLGTDLVEVFGEEAIPLTRKDLDVTDFES--------LKILKELKPEVII 52
           M + + G  GQ+G +L          L   D+  TD+           + +K+++P+VI+
Sbjct: 1   MNILLFGKTGQVGWELQRALAPLG-NLIALDVHSTDYCGDFSNPEGVAETVKKIRPDVIV 59

Query: 53  NTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYT-E 111
           N AA+  VD AE  PE A  +NA     +A+ ANE+GA  ++ STDYVF G    P+   
Sbjct: 60  NAAAHTDVDKAESEPEFAQLLNATSVEAIAKAANEVGAWVIHYSTDYVFPGTGEIPWQGG 119

Query: 112 EDIPNPINVYGASKYIGE-IFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANK 170
            D   P+NVYG +K   E    + +  K+ I R + +Y      GKG NF + +++ A +
Sbjct: 120 TDATAPLNVYGETKLSSEKKALQKHCGKHIIFRTSWVYA-----GKGNNFAKTMLRLAKE 174

Query: 171 GEELRIVNDQFMSPTYTKDVARTLRELLRL---RPSF-GVYHMVNEGYCSWYEFTRAIFE 226
            EEL ++NDQF  PT  + +A      +R+   +P   G+YH+V  G  +W+++   +FE
Sbjct: 175 REELAVINDQFGRPTGAELLADCTAHAIRVAVDKPEVAGLYHLVAGGTTTWHDYAALVFE 234

Query: 227 ---ILGWDVRVKPIN---SSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEALGEYLKE 279
                G ++ +  +N   ++     A+RP  S L  EK ++   L +  W+  +   L E
Sbjct: 235 EARKAGINLALNKLNAVPTTAYPTPARRPHNSRLNTEKFQQNFALVLPDWQVGVKRMLNE 294


>pir||C49906 rfbC homolog - Xanthomonas campestris pv. campestris
           >gi|398117|gb|AAA16189.1| (L23941) putative [Xanthomonas
           campestris]
           Length = 302
           
 Score =  119 bits (295), Expect = 4e-26
 Identities = 92/301 (30%), Positives = 140/301 (45%), Gaps = 27/301 (8%)

Query: 1   MRVAVIGANGQLGTDLVEVFGEE-AIPLTRKD--------LDVTDFESLK----ILKELK 47
           M   V GANGQ+G +L+     + A+  T +          +  DF++ +    +L  + 
Sbjct: 1   MTTLVFGANGQVGAELLRALAADGAVQATTRSGRLPDGSACETADFDAPETLPALLDRIG 60

Query: 48  PEVIINTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGE 107
           P +++N AAY  VD AE     A + NA   L +A          V+ STDYVFDG    
Sbjct: 61  PSLVVNAAAYTAVDCAEQDRVSAMRANAQAPLTIAAWCAARDVPLVHYSTDYVFDGQDTA 120

Query: 108 PYTEEDIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKK 167
           PY E+   +P+ VYG +K  GE   R    ++    +   YG  G R     F    +  
Sbjct: 121 PYLEDAQTSPLGVYGETKLAGENAIRASGAQH----LDPAYG-MGVRIARREFPAHHVAC 175

Query: 168 ANKGEELRIVNDQFMSPTYTKDVARTLRELLRLR--PSFGVYHMVNEGYCSWYEFTRAIF 225
             + +ELR+V DQ  +P+    +A    +LLR R   + G +H+   G  SW+ F  AIF
Sbjct: 176 RAERDELRVVADQIGTPSRRALIADITAQLLRQRTAETSGTWHLTAAGQTSWHGFAEAIF 235

Query: 226 E------ILGWDVRVKPINSSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEALGEYLK 278
           E      +L    RV PI +++    AKRP +S L  EKL++   + +  W+  L   + 
Sbjct: 236 EEAVSAGLLPRAPRVVPITTADYPTPAKRPAYSRLSIEKLQRDFDIVLPEWRPGLQRVIA 295

Query: 279 E 279
           E
Sbjct: 296 E 296


>gb|AAB47841.1| (U61226) RfbC [Leptospira interrogans]
           Length = 306
           
 Score =  118 bits (294), Expect = 6e-26
 Identities = 89/297 (29%), Positives = 143/297 (47%), Gaps = 29/297 (9%)

Query: 7   GANGQLGTDLVEVF---GEEAIPLTRKDLDVTDFESLKILKELKPEVIINTAAYVRVDDA 63
           G NGQLG +L E F   G EA+   R++ D+ D +S   + +  P ++++  AY  VD A
Sbjct: 6   GKNGQLGWELAERFKSNGLEAVGFGREEWDLADLDSAARILKDSPRILVHCGAYTAVDKA 65

Query: 64  ELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFD------GAKGEPYTEEDIPNP 117
           E   E A+K+N++    ++    +     +YISTD+VFD      G     +  +   +P
Sbjct: 66  ESDSENAYKINSLSVKKISEECLKRKIHLIYISTDFVFDANSETIGDTIRFWKPDSTLSP 125

Query: 118 INVYGASKYIGEIFTRN---YSKKYYIIRVASLYGKAGARGKGGNFVEWVIK--KANKGE 172
             +YG SK  GE + RN    SK+  I+R + +Y        G NF + ++K  + +   
Sbjct: 126 KGIYGLSKAEGEKWIRNTFANSKQANIVRTSWVYS-----SHGNNFPKTIVKLLQDSNRH 180

Query: 173 ELRIVNDQFMSPTYTKDVAR----TLRELLRLRPSFGVYHMVNEGYCSWYEFTRAI---- 224
           ELR++ DQ   PT+   +A      +  +L+      + H  N G  SWY+F  A+    
Sbjct: 181 ELRVIEDQLGRPTWAGRLADFIIFLIYGILKGESYPEILHFSNSGVASWYDFALAVRDFS 240

Query: 225 --FEILGWDVRVKPINSSELKRLAKRPKFSALKNEKLEKIGLKMKHWKEALGEYLKE 279
             F ++     + PI +      A RP++S L  E+  KI   + HW+E L   LKE
Sbjct: 241 HSFSLIENLKPIYPIPTEGYPTPAPRPRYSILDLEETRKIFGVVPHWREDLTLCLKE 297


>pir||E82828 dTDP-4-keto-L-rhamnose reductase XF0258 [imported] - Xylella
           fastidiosa (strain 9a5c)
           >gi|9105073|gb|AAF83071.1|AE003879_6 (AE003879)
           dTDP-4-keto-L-rhamnose reductase [Xylella fastidiosa]
           Length = 302
           
 Score =  118 bits (293), Expect = 7e-26
 Identities = 91/295 (30%), Positives = 137/295 (45%), Gaps = 27/295 (9%)

Query: 1   MRVAVIGANGQLGTDLVE-VFGEEAIPLTR-------KDLDVTDFESLKILKEL----KP 48
           M V V GA GQ+G +L+  + G     +TR       ++    DF+  + L+ L    +P
Sbjct: 1   MTVLVFGAGGQIGQELLRSLSGRVVCAVTRSGRLPNGRECVQADFDRPETLRPLLDAQRP 60

Query: 49  EVIINTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEP 108
             ++N AAY  VD AE  P+  F++NA     +A      G   V+ STDYVFDG    P
Sbjct: 61  AQVVNAAAYTAVDRAESEPDVVFRINAQAPGVIAHWCARHGVPLVHYSTDYVFDGQGTSP 120

Query: 109 YTEEDIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKA 168
           Y  +D   P+N+YGASK  GE   R       I+R + +Y        G NF+  +++  
Sbjct: 121 YGVDDPVAPLNIYGASKLAGERAVRAAGGCSLILRTSWVYA-----AHGHNFLRTMLRLG 175

Query: 169 NKGEELRIVNDQFMSPTYTKDVARTLRELLR---LRPSFGVYHMVNEGYCSWYEFTRAIF 225
              E L +V DQ  +PT    +A    +LL         G++H+   G  SW+ F   IF
Sbjct: 176 ATSERLPVVADQIGTPTAAGLIADVTAQLLAGGGQSRHAGIWHLTATGQTSWHGFAEEIF 235

Query: 226 ---EILGWDVR---VKPINSSELKRLAKRPKFSALKNEKL-EKIGLKMKHWKEAL 273
              +  G  +R   V+ I S      A+RP +S L    L E  G+ +  W++ +
Sbjct: 236 AQAQACGLMMRVPQVQAIASVGYPTAARRPAYSCLDTTALVETFGIVLPDWRQGV 290


>gb|AAD52187.1|AF144879_26 (AF144879) unknown [Leptospira interrogans]
           Length = 306
           
 Score =  118 bits (292), Expect = 1e-25
 Identities = 89/297 (29%), Positives = 143/297 (47%), Gaps = 29/297 (9%)

Query: 7   GANGQLGTDLVEVF---GEEAIPLTRKDLDVTDFESLKILKELKPEVIINTAAYVRVDDA 63
           G NGQLG +L E F   G EA+   R++ D+ D +S   + +  P ++++  AY  VD A
Sbjct: 6   GKNGQLGWELAERFKSNGLEAVGFGREEWDLADLDSAARILKDSPRILVHCGAYTAVDKA 65

Query: 64  ELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFD------GAKGEPYTEEDIPNP 117
           E   E A+K+N++    ++    +     +YISTD+VFD      G     +  +   +P
Sbjct: 66  ESDSENAYKINSLSVKKISEECLKRKIHLIYISTDFVFDANSETIGDTIRFWKPDSTLSP 125

Query: 118 INVYGASKYIGEIFTRN---YSKKYYIIRVASLYGKAGARGKGGNFVEWVIK--KANKGE 172
             +YG SK  GE + RN    SK+  IIR + +Y        G NF + ++K  + +   
Sbjct: 126 KGIYGLSKAEGEKWIRNTFANSKQANIIRTSWVYS-----SHGNNFPKTIVKLLQDSNRH 180

Query: 173 ELRIVNDQFMSPTYTKDVAR----TLRELLRLRPSFGVYHMVNEGYCSWYEFTRAI---- 224
           ELR++ DQ   PT+   +A      +  +L+      + H  N G  SWY+F  A+    
Sbjct: 181 ELRVIEDQLGRPTWAGRLADFIIFLIYGILKGESYPEILHFSNSGVASWYDFALAVRDFS 240

Query: 225 --FEILGWDVRVKPINSSELKRLAKRPKFSALKNEKLEKIGLKMKHWKEALGEYLKE 279
             F ++     + PI +      A RP++S L  ++  KI   + HW+E L   LKE
Sbjct: 241 HSFSLIENLKPIYPIPTEGYPTPAPRPRYSILDLDETRKIFGVVPHWREDLTLCLKE 297


>gb|AAD12970.1| (AF078135) RmlD [Leptospira borgpetersenii]
           Length = 306
           
 Score =  117 bits (290), Expect = 2e-25
 Identities = 91/298 (30%), Positives = 148/298 (49%), Gaps = 31/298 (10%)

Query: 7   GANGQLGTDLVEVFGE---EAIPLTRKDLDVTDFESL-KILKELKPEVIINTAAYVRVDD 62
           G +GQLG +L + F     E+I  +R++ D+TD +S+ KILK+  P+++++  AY  VD 
Sbjct: 6   GKSGQLGWELTKRFKSLDLESIGFSREEWDLTDLDSVEKILKD-SPKILVHCGAYTAVDK 64

Query: 63  AELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFD------GAKGEPYTEEDIPN 116
           AE   E  +K+N++    ++    +     +YISTD+VFD      G     +  +   +
Sbjct: 65  AESDSENVYKINSLSVKKISEECLKRKIHLIYISTDFVFDANSETIGDTIRFWKPDSTLS 124

Query: 117 PINVYGASKYIGEIFTRNY---SKKYYIIRVASLYGKAGARGKGGNFVEWVIK--KANKG 171
           P  +YG SK  GE + +N    SK+  I+R + +Y        G NF + ++K  +  K 
Sbjct: 125 PKGIYGLSKAEGERWIQNIFADSKQANIVRTSWVYS-----SYGNNFPKTILKLLQDPKR 179

Query: 172 EELRIVNDQFMSPTYTKDVAR----TLRELLRLRPSFGVYHMVNEGYCSWYEFTRAI--- 224
            EL+++ DQ   PT+   +A      + E+L+      + H  N G  SWY+F  AI   
Sbjct: 180 TELKVIEDQLGRPTWAGRLADFIIFLIYEILKKGGYPEILHPSNSGIASWYDFAIAIRDI 239

Query: 225 ---FEILGWDVRVKPINSSELKRLAKRPKFSALKNEKLEKIGLKMKHWKEALGEYLKE 279
              F ++     + PI +      A RP++S L   +  KI   + HWKE L   LKE
Sbjct: 240 SYSFSLIENLKPISPIPTESYPTAAPRPRYSILDLNETRKIFGPVPHWKEDLTLCLKE 297


>sp|P37778|RFBD_SHIFL DTDP-4-DEHYDRORHAMNOSE REDUCTASE (DTDP-4-KETO-L-RHAMNOSE REDUCTASE)
           (DTDP-6-DEOXY-L-MANNOSE DEHYDROGENASE) (DTDP-L-RHAMNOSE
           SYNTHETASE) >gi|541222|pir||S41535 rfbC protein -
           Shigella flexneri >gi|454899|emb|CAA50768.1| (X71970)
           rfbA [Shigella flexneri]
           Length = 300
           
 Score =  114 bits (282), Expect = 1e-24
 Identities = 84/299 (28%), Positives = 144/299 (48%), Gaps = 26/299 (8%)

Query: 1   MRVAVIGANGQLGTDLVEVFGEEAIPLTRKDLDVTDFES--------LKILKELKPEVII 52
           M + + G  GQ+G +L          L   D+  TD+           + +K+++P+VI+
Sbjct: 1   MNILLFGKTGQVGWELQRALAPLG-NLIALDVHSTDYCGDFSNPEGVAETVKKIRPDVIV 59

Query: 53  NTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEE 112
           N AA+  VD AE  P  A  +NA     + + ANE+GA  ++ STDYVF G     + E 
Sbjct: 60  NAAAHTAVDKAESEPNFAQLLNATCVEAIIKAANEVGAWVIHYSTDYVFPGNGDTAWLET 119

Query: 113 DIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGE 172
           D   P+NVYG +K       +++  K+ I R + +Y      GKG NF + +++ A   E
Sbjct: 120 DATAPLNVYGGTKLAWGKALQDHCGKHLIFRTSWVYA-----GKGNNFAKTMLRLAKDRE 174

Query: 173 ELRIVNDQFMSPTYTKD-VARTLRELLRLRPS----FGVYHMVNEGYCSWYEFTRAIFE- 226
            L ++ DQF +PT   D +A   R  + L  +     G+YH+V  G  +W+++   +F+ 
Sbjct: 175 TLAVITDQFGAPTGALDLLADCTRHAIWLAANKPEVAGLYHLVAGGTTTWHDYPALVFKE 234

Query: 227 --ILGWDVRVKPIN---SSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEALGEYLKE 279
               G+++ +  +N   ++     A+ P    L  EK ++   L +  W+  +   L E
Sbjct: 235 ARRAGFNLPLNKLNAVPTTAYPTPARGPHNFRLNTEKFQQNFALVLPDWQVGVKRMLNE 293


>emb|CAC13137.1| (AJ250139) dTDP-4-dehydrorhamnose reductase [Acetobacter xylinus]
           Length = 295
           
 Score =  113 bits (281), Expect = 2e-24
 Identities = 84/272 (30%), Positives = 132/272 (47%), Gaps = 21/272 (7%)

Query: 3   VAVIGANGQLGTDLVEVFGEEAIP-LTRKDLDVTDFESL-KILKELKPEVIINTAAYVRV 60
           + V G +GQL T L    G E +  + R D D     ++ +I+ E  PE ++N AA+  V
Sbjct: 7   ILVTGGHGQLATALA---GHEGVMRVGRPDFDFDRPGTIDQIMAENTPEFVVNAAAWTAV 63

Query: 61  DDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNPINV 120
           D AE   E A + N  G   +A      G   ++ISTDYVF G KG PY E D  +P +V
Sbjct: 64  DAAETDAEGAARANHAGPARLAAACRARGIPLIHISTDYVFSGDKGSPYMETDPVDPRSV 123

Query: 121 YGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIVNDQ 180
           YG++K  GE           I+R A +Y          NFV  +++ A +   LR+V+DQ
Sbjct: 124 YGSTKAAGEQAVLAAQPDSIILRTAWVYSPYNR-----NFVRTMVEAAARRPTLRVVSDQ 178

Query: 181 FMSPTYTKDVARTLRELLR-LRPS------FGVYHMVNEGYCSWYEFTRAIFEILGWDVR 233
             +PT    +A+T+  ++R +R +       G+YH   +G  SWY+   A          
Sbjct: 179 IGNPTSADALAQTIMHIIRQIRETGWKADYAGIYHAAGQGATSWYDLACAAVAAAARHGN 238

Query: 234 ----VKPINSSELKRLAKRPKFSALKNEKLEK 261
               ++PI +++    A+RP  + L   +L++
Sbjct: 239 PQPVMEPITTADWPTPARRPADARLDCTRLQE 270


>gb|AAK41127.1| dTDP-4-dehydrorhamnose reductase (rfbD-1) [Sulfolobus solfataricus]
           Length = 226
           
 Score =  109 bits (271), Expect = 3e-23
 Identities = 79/217 (36%), Positives = 119/217 (54%), Gaps = 15/217 (6%)

Query: 47  KPEVIINTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKG 106
           +P+VIINTAA   VD  E+  E+A+K+NA    ++ R +  + A  +++STDYVFDG KG
Sbjct: 9   RPDVIINTAAMTDVDKCEVEREKAYKINAEAVKHMVRASRVVEAYFIHVSTDYVFDGTKG 68

Query: 107 EPYTEEDIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIK 166
             Y E+D+PNPIN YG +K +GE F  +Y     +IR + ++     R KG  F  +V K
Sbjct: 69  N-YKEDDLPNPINYYGLTKLLGETFALSYDDS-LVIRTSGVF-----RHKG--FPVYVYK 119

Query: 167 KANKGEELRIVNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFE 226
              +G+ +      + SP   + +A  + ELL LR + G+ ++  E   S YE    I E
Sbjct: 120 TLKEGKTV-FAYKGYYSPISARKLASAIEELLALRKT-GLLNVAGE-RISRYELALKIKE 176

Query: 227 ILGWDVRVKPINSSELKR-LAKRPKFSALKNEKLEKI 262
                  VK ++  E+K   A+RP  S+L   K +KI
Sbjct: 177 KFNLPGEVKEVD--EVKGWTARRPFDSSLDYSKAKKI 211


>emb|CAB57472.1| (Y18930) dTDP-4-dehydrorhamnose reductase [Sulfolobus solfataricus]
           Length = 226
           
 Score =  109 bits (271), Expect = 3e-23
 Identities = 79/217 (36%), Positives = 119/217 (54%), Gaps = 15/217 (6%)

Query: 47  KPEVIINTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKG 106
           +P+VIINTAA   VD  E+  E+A+K+NA    ++ R +  + A  +++STDYVFDG KG
Sbjct: 9   RPDVIINTAAMTDVDKCEVEREKAYKINAEAVKHMVRASRVVEAYFIHVSTDYVFDGTKG 68

Query: 107 EPYTEEDIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIK 166
             Y E+D+PNPIN YG +K +GE F  +Y     +IR + ++     R KG  F  +V K
Sbjct: 69  N-YKEDDLPNPINYYGLTKLLGETFALSYDDS-LVIRTSGVF-----RHKG--FPVYVYK 119

Query: 167 KANKGEELRIVNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFE 226
              +G+ +      + SP   + +A  + ELL LR + G+ ++  E   S YE    I E
Sbjct: 120 TLKEGKTV-FAYKGYYSPISARKLASAIEELLALRKT-GLLNVAGE-RISRYELALKIKE 176

Query: 227 ILGWDVRVKPINSSELKR-LAKRPKFSALKNEKLEKI 262
                  VK ++  E+K   A+RP  S+L   K +KI
Sbjct: 177 KFNLPGEVKEVD--EVKGWTARRPFDSSLDYSKAKKI 211


>emb|CAB56837.1| (AJ243721) dTDP-4-keto-6-deoxy-D-glucose 4-reductase [Homo sapiens]
           Length = 323
           
 Score =  106 bits (261), Expect = 4e-22
 Identities = 92/301 (30%), Positives = 146/301 (47%), Gaps = 26/301 (8%)

Query: 2   RVAVIGANGQLGTDLVEVF----------GEEAIPLTRKDLDVTDFESLK-ILKELKPEV 50
           RV V GA G LG  + + F          G        + +++ D  ++  I+ + +P V
Sbjct: 19  RVLVTGATGLLGRAVHKEFQQNNWHAVGCGFRRARPKFEQVNLLDSNAVHHIIHDFQPHV 78

Query: 51  IINTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYT 110
           I++ AA  R D  E  P+ A ++N   + N+A+ A  +GA  +YIS+DYVFDG    PY 
Sbjct: 79  IVHCAAERRPDVVENQPDAASQLNVDASGNLAKEAAAVGAFLIYISSDYVFDGT-NPPYR 137

Query: 111 EEDIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEW-VIKKAN 169
           EEDIP P+N+YG +K  GE      +    ++R+  LYG+     +    V +  ++ +N
Sbjct: 138 EEDIPAPLNLYGKTKLDGEKAVLENNLGAAVLRIPILYGEVEKLEESAVTVMFDKVQFSN 197

Query: 170 KGEELRIVNDQFMSPTYTKDVARTLRELLRLR---PSF-GVYHMVNEGYCSWYEFTRAIF 225
           K   +     +F  PT+ KDVA   R+L   R   PS  G +H       + YE   AI 
Sbjct: 198 KSANMDHWQQRF--PTHVKDVATVCRQLAEKRMLDPSIKGTFHWSGNEQMTKYEMACAIA 255

Query: 226 EILGW-DVRVKPINSSELKRLAKRPKFSALKNEKLEKIGLKMK-----HWKEALGEYLKE 279
           +        ++PI  S +   A+RP+ + L   KLE +G+  +       KE+L  +L +
Sbjct: 256 DAFNLPSSHLRPITDSPVLG-AQRPRNAQLDCSKLETLGIGQRTPFRIGIKESLWPFLID 314

Query: 280 K 280
           K
Sbjct: 315 K 315


>gi|11034825 dTDP-4-keto-6-deoxy-D-glucose 4-reductase; beta regulatory subunit
           of methionine adenosyltransferase [Homo sapiens]
           >gi|6815285|gb|AAF28477.1| (AF182814) methionine
           adenosyltransferase regulatory beta subunit [Homo
           sapiens]
           Length = 334
           
 Score =  106 bits (261), Expect = 4e-22
 Identities = 92/301 (30%), Positives = 146/301 (47%), Gaps = 26/301 (8%)

Query: 2   RVAVIGANGQLGTDLVEVF----------GEEAIPLTRKDLDVTDFESLK-ILKELKPEV 50
           RV V GA G LG  + + F          G        + +++ D  ++  I+ + +P V
Sbjct: 30  RVLVTGATGLLGRAVHKEFQQNNWHAVGCGFRRARPKFEQVNLLDSNAVHHIIHDFQPHV 89

Query: 51  IINTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYT 110
           I++ AA  R D  E  P+ A ++N   + N+A+ A  +GA  +YIS+DYVFDG    PY 
Sbjct: 90  IVHCAAERRPDVVENQPDAASQLNVDASGNLAKEAAAVGAFLIYISSDYVFDGT-NPPYR 148

Query: 111 EEDIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEW-VIKKAN 169
           EEDIP P+N+YG +K  GE      +    ++R+  LYG+     +    V +  ++ +N
Sbjct: 149 EEDIPAPLNLYGKTKLDGEKAVLENNLGAAVLRIPILYGEVEKLEESAVTVMFDKVQFSN 208

Query: 170 KGEELRIVNDQFMSPTYTKDVARTLRELLRLR---PSF-GVYHMVNEGYCSWYEFTRAIF 225
           K   +     +F  PT+ KDVA   R+L   R   PS  G +H       + YE   AI 
Sbjct: 209 KSANMDHWQQRF--PTHVKDVATVCRQLAEKRMLDPSIKGTFHWSGNEQMTKYEMACAIA 266

Query: 226 EILGW-DVRVKPINSSELKRLAKRPKFSALKNEKLEKIGLKMK-----HWKEALGEYLKE 279
           +        ++PI  S +   A+RP+ + L   KLE +G+  +       KE+L  +L +
Sbjct: 267 DAFNLPSSHLRPITDSPVLG-AQRPRNAQLDCSKLETLGIGQRTPFRIGIKESLWPFLID 325

Query: 280 K 280
           K
Sbjct: 326 K 326


>gb|AAK41975.1| dTDP-4-dehydrorhamnose reductase (rfbD-2) [Sulfolobus solfataricus]
           Length = 207
           
 Score =  100 bits (246), Expect = 2e-20
 Identities = 73/204 (35%), Positives = 111/204 (53%), Gaps = 15/204 (7%)

Query: 60  VDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNPIN 119
           VD  E+  ++A+K+N+    ++ R    + +  ++ISTDYVFDG KG  Y E++IPNPIN
Sbjct: 4   VDKCEIEKDKAYKINSQAVKHIVRAGRVVDSYVIHISTDYVFDGNKGN-YKEDNIPNPIN 62

Query: 120 VYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIVND 179
            YG SK +GEIF  +Y +   IIR + ++     R KG  F  +V K   +G+ + +   
Sbjct: 63  YYGLSKLLGEIFASSYDES-LIIRTSGVF-----RNKG--FPIYVYKTLKEGKTV-LAFK 113

Query: 180 QFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFEILGWDVRVKPINS 239
            + SP   + +A  + ELL LR + G+ H+  E   S YE    I E       VK ++ 
Sbjct: 114 GYYSPISARKLALAIDELLDLRKT-GIIHVAGE-RISRYELAIKIKEKFNLPGEVKEVD- 170

Query: 240 SELKR-LAKRPKFSALKNEKLEKI 262
            E+K  +AKRP  S+L   K  K+
Sbjct: 171 -EIKSWIAKRPYDSSLDISKARKL 193


>gb|AAC70777.1| (AF097519) dTDP-4-keto-L-rhamnose reductase [Klebsiella pneumoniae]
           Length = 296
           
 Score = 96.7 bits (237), Expect = 3e-19
 Identities = 70/227 (30%), Positives = 117/227 (50%), Gaps = 22/227 (9%)

Query: 1   MRVAVIGANGQLGTDL---VEVFGEE-AIPLTRKDL--DVTDFESLK-ILKELKPEVIIN 53
           M +++IG NGQ+G +L   +   G+  A+    K+L  D+T+ E +   ++ ++P+V++N
Sbjct: 1   MNISLIGNNGQVGWELHRSLSFLGDVVAVDYFDKELCGDLTNLEGVAHTVRPVRPDVVVN 60

Query: 54  TAAY---VRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYT 110
            AA+    R+     +P    +    GA        E+GA+ V+ STDYVFDGA      
Sbjct: 61  AAAHSPWTRLKSIGSFPTCLIRQMGGGA---GGGVGELGALMVHYSTDYVFDGAGSHYRR 117

Query: 111 EEDIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANK 170
           E++   P+NVYG +K  GE+  +  + ++ I R + +Y   GA     NF + +++ A +
Sbjct: 118 EDEATGPLNVYGETKRAGELALQQGNPRHLIFRTSWVYATRGA-----NFAKTMLRLAGE 172

Query: 171 GEELRIVNDQFMSPT----YTKDVARTLRELLRLRPSFGVYHMVNEG 213
            E L I++D   +PT         A  +RE LR     G YH+V  G
Sbjct: 173 KETLTIIDDLLWAPTGAELLADCTATAIRETLRNPALAGTYHLVASG 219


>pir||S35300 rfbG protein - Yersinia enterocolitica >gi|48591|emb|CAA79353.1|
           (Z18920) WbbW [Yersinia enterocolitica]
           Length = 289
           
 Score = 90.9 bits (222), Expect = 2e-17
 Identities = 78/284 (27%), Positives = 129/284 (44%), Gaps = 11/284 (3%)

Query: 2   RVAVIGANGQLGTDLVEVFGE---EAIPLTRKDLDVTDFESL-KILKELKPEVIINTAAY 57
           ++ + G  G LG  +     +     I   R  L+++  E++   +   KP+VI++ AA 
Sbjct: 4   KILITGGTGMLGAYVTSALKDTDYNVIVTERNTLNLSVPEAIFSYITAEKPDVILHFAAE 63

Query: 58  VRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNP 117
             VD  E  P  A   N +    +A+ A   GA  +Y+S+  VF G     Y E DIP P
Sbjct: 64  TDVDLCEREPARAGIYNHLATEQIAQAAKFCGAWLLYLSSSNVFGGEGKLSYNELDIPLP 123

Query: 118 INVYGASKYIGEIFTRN-YSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGE-ELR 175
           +N YG SK IGE   RN  +  + IIR   + G  G   K   FV  +I++   G   ++
Sbjct: 124 MNYYGRSKLIGESSVRNACTNNHLIIRAGWMIG--GGPDKDHKFVGKIIQQIKAGSTSIK 181

Query: 176 IVNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFEILGWDVRVK 235
            V+D+  S T    +   +   +  R + G  H  + G  S ++   AI ++L +   + 
Sbjct: 182 AVSDRLGSITSAMQLCNFIIWAINKRHT-GTLHFASSGTISRFDIACAIGDLLNFKGDII 240

Query: 236 PINSSELKRLAKRPKFSALKNEKLEKI--GLKMKHWKEALGEYL 277
           P++SS     A RP    +++  +  +    K   WK  L +Y+
Sbjct: 241 PVHSSVFPLSAPRPYSEGIESIYMSILSDAPKPSLWKSDLAKYV 284


>pir||F75597 dTDP-4-rhamnose reductase-related protein - Deinococcus radiodurans
           (strain R1) >gi|6460559|gb|AAF12265.1|AE001862_91
           (AE001862) dTDP-4-rhamnose reductase-related protein
           [Deinococcus radiodurans]
           Length = 247
           
 Score = 86.6 bits (211), Expect = 3e-16
 Identities = 51/145 (35%), Positives = 81/145 (55%), Gaps = 3/145 (2%)

Query: 2   RVAVIGANGQLGTDLVEVFGEEAIPLTRKDLDVTDFESLKILKELKPEVIINTAAYVRVD 61
           ++ + G +G+LGT+L  V  E   P + +       + L +++  +P++I++ AAY  V 
Sbjct: 8   KMLLTGGSGRLGTELRSVIPEIVAPSSAEMNLTAAAQVLAVVQRERPDIIVHAAAYTNVG 67

Query: 62  DAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNP-INV 120
            AE   E  +  N +G  NVA  AN +GA  V+ISTDYVF G +G  Y E D P P +N 
Sbjct: 68  GAEKDREACWNANVVGTRNVAAAANAVGAKLVHISTDYVFSGEEG-GYHESDTPGPVVNY 126

Query: 121 YGASKYIGEIFTRNYSKKYYIIRVA 145
           Y  +K + E   R  ++K+ I+R +
Sbjct: 127 YSLTKLVAEEAAR-AAQKHLILRTS 150


>emb|CAB56751.1| (X56616) putative dTDP-4-dehydrorhamnose reductase [Acidianus
           ambivalens]
           Length = 232
           
 Score = 83.1 bits (202), Expect = 3e-15
 Identities = 61/198 (30%), Positives = 109/198 (54%), Gaps = 15/198 (7%)

Query: 21  GEEAIPLTRK-DLDVTDFESLKILKELKPEVIINTAAYVRVDDAELYPEEAFKVNAIGAL 79
           GE A  LT   D +    +S K + E KPE++I+T     ++D    P   + +N   A+
Sbjct: 8   GELARALTNAIDDEFIFIDSPKKVYETKPEIVIHT-----LEDNSNNPS-MWNLNTWFAI 61

Query: 80  NVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNPINVYGASKYIGEIFTRNYSKKY 139
           N+A+ AN+IG++NVY ST  ++DG +G  Y+E   P+P+N YG +K +GE    +    Y
Sbjct: 62  NIAKAANKIGSLNVYFSTFMIYDGKRGY-YSETSTPSPLNYYGMTKLVGETAIASLG-NY 119

Query: 140 YIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIVNDQFMSPTYTKDVARTLRELLR 199
            I+R+ ++Y  +  RG   + ++ +IKK       +   + ++SP   KDVA  ++ LL+
Sbjct: 120 LILRLGAVYSPS-YRGILFHIIKALIKKG----IAKCNTNLYLSPISVKDVAYAVKYLLK 174

Query: 200 LRPSFGVYHMVNEGYCSW 217
            + + GV ++  + +  +
Sbjct: 175 -KDARGVINLAGKRFSEY 191


>gb|AAD12954.1| (AF078135) unknown [Leptospira borgpetersenii]
           Length = 298
           
 Score = 72.2 bits (174), Expect = 7e-12
 Identities = 65/296 (21%), Positives = 132/296 (43%), Gaps = 37/296 (12%)

Query: 2   RVAVIGANGQLGTDLVEVFGEEA---IPLTRKDLDVTDF-------------------ES 39
           ++ V+G +G LG  +  V  E A   +  T + ++   F                   E 
Sbjct: 6   KILVLGVSGMLGNAVFRVLSENAEFEVQGTIRSIEYLRFFTKAESERITSNMDVLNEDEL 65

Query: 40  LKILKELKPEVIINTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDY 99
           L++   +KP++++N    ++       P     +N++    ++ +   IGA  + ISTD 
Sbjct: 66  LRLFSNIKPDIVVNCVGIIKQQKLSKDPITVLPINSLLPHRLSNLCKLIGARLILISTDC 125

Query: 100 VFDGAKGEPYTEEDIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGN 159
           VF+G KG  YTE D P+  ++YG SK IGEI   ++    + +R + +  +  +     +
Sbjct: 126 VFNGQKGN-YTETDTPDAEDLYGRSKEIGEIREESH---VFTVRTSIIGHELNS---NYS 178

Query: 160 FVEWVIKKANKGEELRIVNDQFMSPTYTKDVARTLRELLRLRPS-FGVYHMVNEGYCSWY 218
            V+W +   ++  E++     F S   + ++A  ++ ++   P  +G+YH V+    S +
Sbjct: 179 LVDWFL---SQNGEVKGYKKAFFSGLPSCEIAEIIKTVIIPNPKLYGLYH-VSSDPISKF 234

Query: 219 EFTRAIFEILGWDVRVKPINSSELKRLAKRPKF---SALKNEKLEKIGLKMKHWKE 271
           +    + E+ G + ++       + R     KF   ++ K    + +   MK +KE
Sbjct: 235 DLLSLVGEVYGKNNKILESEEVIVDRSLDSTKFRKETSYKPLPWKSLIFLMKKYKE 290


>gb|AAD52171.1|AF144879_10 (AF144879) unknown [Leptospira interrogans]
           Length = 298
           
 Score = 72.2 bits (174), Expect = 7e-12
 Identities = 63/296 (21%), Positives = 133/296 (44%), Gaps = 37/296 (12%)

Query: 2   RVAVIGANGQLGTDLVEVFGEEA---IPLTRKDLDVTDF-------------------ES 39
           ++ V+G +G LG  +  V  + A   +  T + ++   F                   E 
Sbjct: 6   KILVLGVSGMLGNAVFRVLSDSAEFEVQGTIRSIEYLRFFTKAESERITSNMDVLNEDEL 65

Query: 40  LKILKELKPEVIINTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDY 99
           L++   +KP++++N    ++       P     +N++    ++ +   +GA  + ISTD 
Sbjct: 66  LRLFSNIKPDIVVNCVGIIKQQKLAKDPITVLPINSLLPHRLSNLCKLVGARLILISTDC 125

Query: 100 VFDGAKGEPYTEEDIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGN 159
           VF+G KG  YTE D+P+  ++YG SK IGE+    +    + +R + +  +  +     +
Sbjct: 126 VFNGQKGN-YTETDMPDAEDLYGRSKEIGEVRDEPH---VFTVRTSIIGHELNS---NYS 178

Query: 160 FVEWVIKKANKGEELRIVNDQFMSPTYTKDVARTLRELLRLRPS-FGVYHMVNEGYCSWY 218
            V+W +   ++  E+R     F S   + ++A  ++ ++   P  +G+YH ++    S +
Sbjct: 179 LVDWFL---SQNGEVRGYKKAFFSGLPSYEIAEIIKTVIIPNPKLYGLYH-ISSDPISKF 234

Query: 219 EFTRAIFEILGWDVRVKPINSSELKRLAKRPKF---SALKNEKLEKIGLKMKHWKE 271
           +    + E+ G + ++       + R     KF   ++ K    + + L MK +KE
Sbjct: 235 DLLSLVGEVYGKNNKILESEEVIVDRSLDSTKFRKETSYKPLPWKNLILLMKKYKE 290


>pir||A71183 probable UDP-glucose 4-epimerase - Pyrococcus horikoshii
           >gi|3258173|dbj|BAA30856.1| (AP000007) 306aa long
           hypothetical UDP-glucose 4-epimerase [Pyrococcus
           horikoshii]
           Length = 306
           
 Score = 71.8 bits (173), Expect = 9e-12
 Identities = 76/305 (24%), Positives = 135/305 (43%), Gaps = 42/305 (13%)

Query: 3   VAVIGANGQLGTDLVEVFGEEAIPLTRKDL-----------------DVTDFESL-KILK 44
           + + G  G +G+ L E   +E   +   +L                 DV D+ES+ +++ 
Sbjct: 6   IVITGGAGFIGSHLAEALKDENDVIIIDNLYSGRIENIPEGVKFIRADVRDYESIAEVIS 65

Query: 45  ELKPEVIINTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGA 104
           E   + + + AA + V ++   P    +VN IG +NV R  ++     ++ S+  V+   
Sbjct: 66  EA--DYVFHEAAQISVKESIEDPVFTEEVNVIGTINVLRALSQGDGKLIFASSAAVYGEP 123

Query: 105 KGEPYTEEDIPNPINVYGASKYIGEIFTRNYSKKY----YIIRVASLYGKAGARGKGGNF 160
           K  P TE+ + NPI+ YG +K   E + R Y   Y     I+R  ++YG   +    G  
Sbjct: 124 KELPITEDTLTNPISPYGITKLAAEHYCRVYQSLYGIPVVILRYFNVYGPRQSSAYAG-V 182

Query: 161 VEWVIKKANKGEELRIVND--QFMSPTYTKDVARTLRELLRLRPSFG-VYHMVNEGYCSW 217
           +   +++A KGE L I  D  Q     Y KDV      + + R + G ++++      + 
Sbjct: 183 ISIFLERAIKGEPLIIFGDGKQTRDFIYVKDVVEANILVAKKRSANGRIFNVATGKETTI 242

Query: 218 YEFTRAIFEILGWDVRVKPINSSELKRLAKRP---KFSALKNEKLEKIGLKMKHWKEALG 274
            E    I ++          +SS +     RP   + S  K E+++K+G K ++   +L 
Sbjct: 243 LELAMKIIDMTS--------SSSSILFYPPRPGDIRRSVAKIERIKKLGFKPRY---SLE 291

Query: 275 EYLKE 279
           E LKE
Sbjct: 292 EGLKE 296


>gb|AAK42337.1| dTDP-4-dehydrorhamnose reductase (rfbD-3) [Sulfolobus solfataricus]
           Length = 255
           
 Score = 70.2 bits (169), Expect = 3e-11
 Identities = 54/192 (28%), Positives = 105/192 (54%), Gaps = 11/192 (5%)

Query: 41  KILKELKPEVIINTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYV 100
           K+++E KP+VII+T   + + ++   P  A+  N   A+N+AR  ++ G++NV++S+  +
Sbjct: 34  KVIRE-KPDVIIHTFE-IPIFESNANPPLAWSFNTWYAINIARAGSKAGSVNVFLSSFLI 91

Query: 101 FDGAKGEPYTEEDIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNF 160
           +DG +G  Y E + P+P+N YG +K +GE    +    Y ++RV +L+     RG    F
Sbjct: 92  YDGKRGF-YKEHNTPHPLNYYGLTKLVGESSIISLG-NYLVLRVGALF-SLSYRG----F 144

Query: 161 VEWVIKKANKGEELRIVNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEF 220
           +   IK +  G+ L+   + ++S      +A+ ++ LL  + + GV + V     S ++ 
Sbjct: 145 LFPFIKASTMGKVLKCNKNFYISIIDLNTLAKVIK-LLIDKEARGVIN-VGSNRVSLFDI 202

Query: 221 TRAIFEILGWDV 232
              + +I G +V
Sbjct: 203 CSYLSDIFGNEV 214


>pir||S74068 hypothetical protein c0137 - Sulfolobus solfataricus
           >gi|1707767|emb|CAA69439.1| (Y08256) orf c01037
           [Sulfolobus solfataricus]
           Length = 255
           
 Score = 70.2 bits (169), Expect = 3e-11
 Identities = 54/192 (28%), Positives = 105/192 (54%), Gaps = 11/192 (5%)

Query: 41  KILKELKPEVIINTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYV 100
           K+++E KP+VII+T   + + ++   P  A+  N   A+N+AR  ++ G++NV++S+  +
Sbjct: 34  KVIRE-KPDVIIHTFE-IPIFESNANPPLAWSFNTWYAINIARAGSKAGSVNVFLSSFLI 91

Query: 101 FDGAKGEPYTEEDIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNF 160
           +DG +G  Y E + P+P+N YG +K +GE    +    Y ++RV +L+     RG    F
Sbjct: 92  YDGKRGF-YKEHNTPHPLNYYGLTKLVGESSIISLG-NYLVLRVGALF-SLSYRG----F 144

Query: 161 VEWVIKKANKGEELRIVNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEF 220
           +   IK +  G+ L+   + ++S      +A+ ++ LL  + + GV + V     S ++ 
Sbjct: 145 LFPFIKASTMGKVLKCNKNFYISIIDLNTLAKVIK-LLIDKEARGVIN-VGSNRVSLFDI 202

Query: 221 TRAIFEILGWDV 232
              + +I G +V
Sbjct: 203 CSYLSDIFGNEV 214


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.318    0.139    0.400 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 106227182
Number of Sequences: 2977
Number of extensions: 4593100
Number of successful extensions: 15914
Number of sequences better than 1.0e-10: 81
Number of HSP's better than  0.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 32
Number of HSP's that attempted gapping in prelim test: 15645
Number of HSP's gapped (non-prelim): 81
length of query: 283
length of database: 189,106,746
effective HSP length: 55
effective length of query: 228
effective length of database: 156,189,961
effective search space: 35611311108
effective search space used: 35611311108
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 164 (68.3 bits)