BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB0789 (PAB0789) DE:DTDP-4-DEHYDRORHAMNOSE REDUCTASE (283 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||G75098 dtdp-4-dehydrorhamnose reductase PAB0789 - Pyrococcu... 573 e-163 pir||B71152 probable dTDP-4-dehydrorhamnose reductase - Pyrococc... 489 e-137 gi|11500015 dTDP-4-dehydrorhamnose reductas [Archaeoglobus fulgi... 430 e-120 pir||D69106 dTDP-4-dehydrorhamnose reductase - Methanobacterium ... 253 2e-66 dbj|BAB07084.1| (AP001518) spore coat polysaccharide synthesis (... 200 2e-50 gb|AAC35923.1| (AF071085) putative dTDP-4-keto-L-rhamnose reduct... 196 2e-49 sp|P39631|SPSK_BACSU SPORE COAT POLYSACCHARIDE BIOSYNTHESIS PROT... 185 5e-46 pir||S74471 dTDP-6-deoxy-L-mannose-dehydrogenase - Synechocystis... 179 3e-44 gb|AAC44972.1| (U09239) 32.3 kDa cps19fO gene product [Streptoco... 176 2e-43 gb|AAC38675.1| (AF030359) dTDP-L-rhamnose synthase [Streptococcu... 175 4e-43 gb|AAC69541.1| (AF057294) Cps23fR [Streptococcus pneumoniae] 175 6e-43 gb|AAC78677.1| (AF094575) dTDP-L-rhamnose synthase Cps19aO [Stre... 175 6e-43 gb|AAC38691.1| (AF030362) dTDP-L-rhamnose synthase [Streptococcu... 174 1e-42 gb|AAC38680.1| (AF030360) dTDP-L-rhamnose synthase [Streptococcu... 174 1e-42 emb|CAB65207.1| (AJ007311) RmlD protein [Legionella pneumophila] 172 5e-42 pir||G72588 probable dTDP-4-dehydrorhamnose reductase APE1179 - ... 168 5e-41 gb|AAD19916.1| (AF105113) dTDP-L-rhamnose synthase [Streptococcu... 168 9e-41 gb|AAG29801.1| (AF235050) dTDP-4-keto-6-deoxyhexose reductase [S... 163 2e-39 dbj|BAA21509.1| (AB000631) dTDP-4-keto-L-rhamnose reductase [Str... 162 3e-39 gb|AAD05457.1| (AF064070) putative dTDP-4-keto-L-rhamnose reduct... 161 9e-39 emb|CAA07388.1| (AJ006985) StrL [Streptomyces glaucescens] 158 8e-38 pir||T31087 probable dTDP-L-rhamnose synthase - Serratia marcesc... 157 1e-37 sp|P55463|RFBD_RHISN PROBABLE DTDP-4-DEHYDRORHAMNOSE REDUCTASE (... 155 4e-37 gb|AAF67512.1|AF170880_19 (AF170880) NovS [Streptomyces spheroides] 155 5e-37 pir||T00104 probable dTDP-4-dehydrorhamnose reductase (EC 1.1.1.... 153 2e-36 pir||C81164 dTDP-L-rhamnose synthase, probable NMB0756 [imported... 153 2e-36 sp|P29781|STRL_STRGR DTDP-4-DEHYDRORHAMNOSE REDUCTASE (DTDP-4-KE... 152 4e-36 pir||F81943 probable dTDP-4-dehydrorhamnose reductase (EC 1.1.1.... 151 8e-36 gb|AAA68212.1| (L37354) thymidine diphospho-4-keto-6-deoxyglucos... 148 9e-35 pir||C83000 dTDP-4-dehydrorhamnose reductase PA5162 [imported] -... 148 9e-35 dbj|BAA82534.1| (AB030032) dTDP-4-keto-L-rhamnose reductase [Act... 146 3e-34 gb|AAF01815.1|AF187532_11 (AF187532) putative dTDP-4-dehydrorham... 145 6e-34 pir||I69649 dTDP-6-deoxy-L-mannose-dehydrogenase - Escherichia coli 143 3e-33 gb|AAG09507.1|AF279617_2 (AF279617) dTDP-6-deoxy-L-mannose-dehyd... 143 3e-33 sp|P37760|RBD1_ECOLI DTDP-4-DEHYDRORHAMNOSE REDUCTASE (DTDP-4-KE... 142 4e-33 pir||B36864 OAC2 protein - Azorhizobium caulinodans >gi|296708|e... 141 7e-33 dbj|BAA19635.1| (AB002668) dTDP-4-rhamnose reductase [Actinobaci... 141 7e-33 dbj|BAA94404.1| (AB041266) dTDP-6-deoxy-L-lyxo-4-hexulose redact... 141 9e-33 pir||C70978 probable rmlD protein - Mycobacterium tuberculosis (... 139 3e-32 gb|AAA53680.1| (L14842) dTDP-6-deoxy-D-glucose-3,5 epimerase [Sh... 137 1e-31 gb|AAF59936.1| (AF237895) 4-ketoreductase [Streptomyces antibiot... 137 2e-31 gb|AAG09531.1|AF279623_2 (AF279623) dTDP-6-deoxy-L-mannose-dehyd... 137 2e-31 gb|AAG09514.1|AF279619_2 (AF279619) dTDP-6-deoxy-L-mannose-dehyd... 136 2e-31 pir||C55213 rfbC protein - Shigella flexneri (strain 2a) 136 3e-31 gb|AAG09527.1|AF279622_2 (AF279622) dTDP-6-deoxy-L-mannose-dehyd... 136 3e-31 gb|AAG09510.1|AF279618_2 (AF279618) dTDP-6-deoxy-L-mannose-dehyd... 136 4e-31 gb|AAG09523.1|AF279621_2 (AF279621) dTDP-6-deoxy-L-mannose-dehyd... 136 4e-31 gb|AAG09503.1|AF279616_2 (AF279616) dTDP-6-deoxy-L-mannose-dehyd... 135 7e-31 gb|AAC44075.1| (U51197) dTDP-6-deoxy-L-mannose-dehydrogenase [Sp... 134 9e-31 gb|AAG09535.1|AF279624_2 (AF279624) dTDP-6-deoxy-L-mannose-dehyd... 134 9e-31 gb|AAG09499.1|AF279615_2 (AF279615) dTDP-6-deoxy-L-mannose-dehyd... 134 1e-30 gb|AAG09518.1|AF279620_2 (AF279620) dTDP-6-deoxy-L-mannose-dehyd... 134 2e-30 pir||T00085 dTDP-4-dehydrorhamnose reductase (EC 1.1.1.133) - St... 131 1e-29 sp|P26392|RFBD_SALTY DTDP-4-DEHYDRORHAMNOSE REDUCTASE (DTDP-4-KE... 131 1e-29 gb|AAG09538.1|AF279625_2 (AF279625) dTDP-6-deoxy-L-mannose-dehyd... 129 5e-29 emb|CAB01952.1| (Z79692) ExpA10 [Sinorhizobium meliloti] 128 7e-29 pir||G70346 spore coat polysaccharide biosynthesis protein SpsK ... 128 7e-29 pir||T51107 4-ketoreductase [validated] - Streptomyces antibioti... 127 1e-28 pir||S23348 hypothetical protein 5.2 - Salmonella choleraesuis >... 126 3e-28 sp|Q46769|RBD2_ECOLI DTDP-4-DEHYDRORHAMNOSE REDUCTASE (DTDP-4-KE... 123 2e-27 pir||C49906 rfbC homolog - Xanthomonas campestris pv. campestris... 119 4e-26 gb|AAB47841.1| (U61226) RfbC [Leptospira interrogans] 118 6e-26 pir||E82828 dTDP-4-keto-L-rhamnose reductase XF0258 [imported] -... 118 7e-26 gb|AAD52187.1|AF144879_26 (AF144879) unknown [Leptospira interro... 118 1e-25 gb|AAD12970.1| (AF078135) RmlD [Leptospira borgpetersenii] 117 2e-25 sp|P37778|RFBD_SHIFL DTDP-4-DEHYDRORHAMNOSE REDUCTASE (DTDP-4-KE... 114 1e-24 emb|CAC13137.1| (AJ250139) dTDP-4-dehydrorhamnose reductase [Ace... 113 2e-24 gb|AAK41127.1| dTDP-4-dehydrorhamnose reductase (rfbD-1) [Sulfol... 109 3e-23 emb|CAB57472.1| (Y18930) dTDP-4-dehydrorhamnose reductase [Sulfo... 109 3e-23 emb|CAB56837.1| (AJ243721) dTDP-4-keto-6-deoxy-D-glucose 4-reduc... 106 4e-22 gi|11034825 dTDP-4-keto-6-deoxy-D-glucose 4-reductase; beta regu... 106 4e-22 gb|AAK41975.1| dTDP-4-dehydrorhamnose reductase (rfbD-2) [Sulfol... 100 2e-20 gb|AAC70777.1| (AF097519) dTDP-4-keto-L-rhamnose reductase [Kleb... 97 3e-19 pir||S35300 rfbG protein - Yersinia enterocolitica >gi|48591|emb... 91 2e-17 pir||F75597 dTDP-4-rhamnose reductase-related protein - Deinococ... 87 3e-16 emb|CAB56751.1| (X56616) putative dTDP-4-dehydrorhamnose reducta... 83 3e-15 gb|AAD12954.1| (AF078135) unknown [Leptospira borgpetersenii] 72 7e-12 gb|AAD52171.1|AF144879_10 (AF144879) unknown [Leptospira interro... 72 7e-12 pir||A71183 probable UDP-glucose 4-epimerase - Pyrococcus horiko... 72 9e-12 gb|AAK42337.1| dTDP-4-dehydrorhamnose reductase (rfbD-3) [Sulfol... 70 3e-11 pir||S74068 hypothetical protein c0137 - Sulfolobus solfataricus... 70 3e-11 >pir||G75098 dtdp-4-dehydrorhamnose reductase PAB0789 - Pyrococcus abyssi (strain Orsay) >gi|5458604|emb|CAB50092.1| (AJ248286) DTDP-4-DEHYDRORHAMNOSE REDUCTASE [Pyrococcus abyssi] Length = 283 Score = 573 bits (1461), Expect = e-163 Identities = 283/283 (100%), Positives = 283/283 (100%) Query: 1 MRVAVIGANGQLGTDLVEVFGEEAIPLTRKDLDVTDFESLKILKELKPEVIINTAAYVRV 60 MRVAVIGANGQLGTDLVEVFGEEAIPLTRKDLDVTDFESLKILKELKPEVIINTAAYVRV Sbjct: 1 MRVAVIGANGQLGTDLVEVFGEEAIPLTRKDLDVTDFESLKILKELKPEVIINTAAYVRV 60 Query: 61 DDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNPINV 120 DDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNPINV Sbjct: 61 DDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNPINV 120 Query: 121 YGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIVNDQ 180 YGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIVNDQ Sbjct: 121 YGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIVNDQ 180 Query: 181 FMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFEILGWDVRVKPINSS 240 FMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFEILGWDVRVKPINSS Sbjct: 181 FMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFEILGWDVRVKPINSS 240 Query: 241 ELKRLAKRPKFSALKNEKLEKIGLKMKHWKEALGEYLKEKGYL 283 ELKRLAKRPKFSALKNEKLEKIGLKMKHWKEALGEYLKEKGYL Sbjct: 241 ELKRLAKRPKFSALKNEKLEKIGLKMKHWKEALGEYLKEKGYL 283 >pir||B71152 probable dTDP-4-dehydrorhamnose reductase - Pyrococcus horikoshii >gi|3256820|dbj|BAA29503.1| (AP000002) 290aa long hypothetical dTDP-4-dehydrorhamnose reductase [Pyrococcus horikoshii] Length = 290 Score = 489 bits (1245), Expect = e-137 Identities = 234/287 (81%), Positives = 261/287 (90%), Gaps = 4/287 (1%) Query: 1 MRVAVIGANGQLGTDLVEVFGE----EAIPLTRKDLDVTDFESLKILKELKPEVIINTAA 56 MR+A+IGANGQLGTDLVEVFG E +PLT KDLDVT ESLK+LKE+KP+V+INTAA Sbjct: 4 MRIAIIGANGQLGTDLVEVFGNDPEFEVVPLTHKDLDVTIPESLKVLKEIKPDVLINTAA 63 Query: 57 YVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPN 116 YVRVDDAELYPE+AF VNAIGALNVARIANEI A+NVYISTDYVFDG KGEPYTEED+PN Sbjct: 64 YVRVDDAELYPEKAFAVNAIGALNVARIANEIDAVNVYISTDYVFDGEKGEPYTEEDVPN 123 Query: 117 PINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRI 176 PINVYG SKY GEIFTRNYS K+YIIRVASLYGKAGA GKGGNFVEWVI+KA GEEL+I Sbjct: 124 PINVYGVSKYTGEIFTRNYSPKHYIIRVASLYGKAGASGKGGNFVEWVIEKAKHGEELKI 183 Query: 177 VNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFEILGWDVRVKP 236 V+DQFMSPTYTKDVARTL+E L+LR FGVYHMVNEG+CSWYEFT AIF++LGW+V +KP Sbjct: 184 VDDQFMSPTYTKDVARTLKEFLKLRSEFGVYHMVNEGFCSWYEFTEAIFDVLGWNVEIKP 243 Query: 237 INSSELKRLAKRPKFSALKNEKLEKIGLKMKHWKEALGEYLKEKGYL 283 I S+EL RLAKRP+FSALKNEKLEKIGL+M+HW+EAL EYLKEKGY+ Sbjct: 244 IKSNELNRLAKRPRFSALKNEKLEKIGLRMRHWREALEEYLKEKGYV 290 >gi|11500015 dTDP-4-dehydrorhamnose reductas [Archaeoglobus fulgidus] Length = 285 Score = 430 bits (1095), Expect = e-120 Identities = 205/283 (72%), Positives = 243/283 (85%), Gaps = 2/283 (0%) Query: 1 MRVAVIGANGQLGTDLVEVFGEE--AIPLTRKDLDVTDFESLKILKELKPEVIINTAAYV 58 M+VAVIGA GQLGTDLV+V EE PLT +D+DV ESL++L+++ P+VIINTAAYV Sbjct: 1 MKVAVIGAKGQLGTDLVDVLKEEFTVYPLTHEDVDVAVSESLEVLRDIHPDVIINTAAYV 60 Query: 59 RVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNPI 118 RVDDAE + E+AF VNAIGALNVARI++EI A+N+YISTDYVFDG KGEPY E D PNPI Sbjct: 61 RVDDAENHAEKAFAVNAIGALNVARISSEIDAVNIYISTDYVFDGEKGEPYVETDKPNPI 120 Query: 119 NVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIVN 178 NVYGASKY GEI T+NYS+K+Y+IRVASLYGKAGA GKGGNFV WV+ A KG+ELRIV Sbjct: 121 NVYGASKYAGEILTKNYSEKHYVIRVASLYGKAGASGKGGNFVNWVVDMARKGQELRIVA 180 Query: 179 DQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFEILGWDVRVKPIN 238 DQFMSPTYTKDVA +RE L+LRP +G+YHMVN+GYCSW+EFT+AIFEIL WDV ++PI Sbjct: 181 DQFMSPTYTKDVALAVREFLKLRPDYGIYHMVNDGYCSWFEFTKAIFEILDWDVEIQPIK 240 Query: 239 SSELKRLAKRPKFSALKNEKLEKIGLKMKHWKEALGEYLKEKG 281 SSEL RLA+RP FSAL+N KLE+IG+KM+HW+EAL +YL EKG Sbjct: 241 SSELNRLARRPAFSALQNYKLERIGIKMRHWREALRDYLAEKG 283 >pir||D69106 dTDP-4-dehydrorhamnose reductase - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622923|gb|AAB86258.1| (AE000933) dTDP-4-dehydrorhamnose reductase [Methanobacterium thermoautotrophicum] Length = 280 Score = 253 bits (639), Expect = 2e-66 Identities = 120/285 (42%), Positives = 191/285 (66%), Gaps = 8/285 (2%) Query: 1 MRVAVIGANGQLGTDLVEVFGEEAIPLTRKDLDVTDFES-LKILKELKPEVIINTAAYVR 59 M++ + G++G LG+DLV++ +T LD+ D E +++L+E +P+ +++ AA+ Sbjct: 1 MKILITGSSGMLGSDLVDILSRRHEVVTSGSLDIRDLEGVMELLRETRPDAVVHAAAFTD 60 Query: 60 VDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNPIN 119 VD AE ++A++VN +G N+A A+ +G+ +YISTDYVFDG KG+ Y E D PNP+N Sbjct: 61 VDCAETERDKAYQVNVLGTRNIAAAASAVGSSILYISTDYVFDGEKGDGYLEFDEPNPLN 120 Query: 120 VYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIVND 179 YG +KY+GE+ R S+++YI+R + L+G+ G NFV +++ A +G E+ +V+D Sbjct: 121 FYGKTKYLGEVSVRQLSERFYIVRTSWLFGR-----NGRNFVGTMVELAERGHEISVVDD 175 Query: 180 QFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFEILGWDVRVKPINS 239 Q+ SPTYT+D+A + LL RP++GVYH+ N G CSWYEF IF LG +V +KP+ S Sbjct: 176 QYGSPTYTRDLAAAIGNLLE-RPAYGVYHLTNSGQCSWYEFAIDIFNELGMEVCLKPVKS 234 Query: 240 SELKRLAKRPKFSALKNEKLEKIGLK-MKHWKEALGEYLKEKGYL 283 E R A+RP FS L+N G K ++++++AL +YLK+ G++ Sbjct: 235 HEFPRPARRPSFSVLRNYNWSMEGFKPLRNYRDALRDYLKDAGFV 279 >dbj|BAB07084.1| (AP001518) spore coat polysaccharide synthesis (dTDP-4-dehydrorhamnose reductase) [Bacillus halodurans] Length = 283 Score = 200 bits (503), Expect = 2e-50 Identities = 112/281 (39%), Positives = 171/281 (59%), Gaps = 12/281 (4%) Query: 5 VIGANGQLGTDLVEVFGE--EAIPLTRKDLDVTDFES-LKILKELKPEVIINTAAYVRVD 61 + GANGQ+G +L + + + LT+++L++ D + + +K + P+ II+ AA+ VD Sbjct: 6 ITGANGQVGMELSKQGKQHFQVTALTKQELNILDRNTVMNKIKGVNPDWIIHVAAFTAVD 65 Query: 62 DAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNPINVY 121 E +A+ VN +GA NVAR A E GA +YISTDYVFDG K PY D+PNP+NVY Sbjct: 66 QCEDEQRKAYHVNGLGAANVARAARETGAKLIYISTDYVFDGNKNSPYETCDLPNPLNVY 125 Query: 122 GASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIVNDQF 181 G SK++GE + Y K I R + LYG GGNFV+ +++ KGE + +V DQ Sbjct: 126 GNSKWLGERLVQKYVKTCTIARTSWLYGH-----YGGNFVKTMLRLLRKGEPIEVVADQV 180 Query: 182 MSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFEILGWDVR-VKPINSS 240 PTY D+ L L+ +PS G+YH+ N G C+W+EF RAI + G+D ++ + Sbjct: 181 GCPTYVNDLVYYLFALME-KPS-GIYHISNRGSCNWFEFARAIAKNAGYDPSLIRATTTK 238 Query: 241 ELKRLAKRPKFSALKNEKLEKIGLK-MKHWKEALGEYLKEK 280 A+RPK+S + +++LE GL+ + W+ AL E+++E+ Sbjct: 239 AFAAKARRPKYSVMSHQQLELAGLQPPREWELALKEFIQEE 279 >gb|AAC35923.1| (AF071085) putative dTDP-4-keto-L-rhamnose reductase [Enterococcus faecalis] Length = 299 Score = 196 bits (494), Expect = 2e-49 Identities = 112/282 (39%), Positives = 168/282 (58%), Gaps = 13/282 (4%) Query: 3 VAVIGANGQLGTDLVEVFGEEAIPLTRKD---LDVTDFES-LKILKELKPEVIINTAAYV 58 + + G NGQLGT+L + E+ I D LD+TD +S L +KE++P VI + AAY Sbjct: 21 ILITGGNGQLGTELRHLLDEQGIEYVSTDSTELDITDADSTLAKVKEIQPSVIYHCAAYT 80 Query: 59 RVDDAELYPEEAF-KVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEP-YTEEDIPN 116 VD AE +E KVN G +VA A +GA VY+STDY+FDG K E Y +D PN Sbjct: 81 AVDKAEDEGKELDEKVNVDGTRHVAEAAKAVGATLVYVSTDYIFDGTKKEGVYAIDDQPN 140 Query: 117 PINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRI 176 P+N YG +K +GE + YYIIR + ++G+ G NFV + K A ++L + Sbjct: 141 PLNEYGRTKLLGEQAVQEILDDYYIIRTSWVFGQYGH-----NFVFTMQKLAETRDQLTV 195 Query: 177 VNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFEILGWDVRVKP 236 V+DQF PT+T+ +A + ++ + FGVYH+ NE CSWY+F + I + +V V P Sbjct: 196 VDDQFGRPTWTRTLAEFMAFVIAEKAPFGVYHLSNENSCSWYQFAKEILK--DTEVEVLP 253 Query: 237 INSSELKRLAKRPKFSALKNEKLEKIGLKMKHWKEALGEYLK 278 ++S++ + A+RP++S + K E +G K+ W+EAL + L+ Sbjct: 254 VDSTQFPQKAQRPQYSVMDLSKTEALGFKIPTWQEALAQMLE 295 >sp|P39631|SPSK_BACSU SPORE COAT POLYSACCHARIDE BIOSYNTHESIS PROTEIN SPSK >gi|2126975|pir||S39728 spore coat polysaccharide synthesis spsK - Bacillus subtilis >gi|580881|emb|CAA51629.1| (X73124) ipa-73d [Bacillus subtilis] >gi|2636317|emb|CAB15808.1| (Z99123) alternate gene name: ipa-73d [Bacillus subtilis] Length = 432 Score = 185 bits (465), Expect = 5e-46 Identities = 104/264 (39%), Positives = 155/264 (58%), Gaps = 11/264 (4%) Query: 2 RVAVIGANGQLGTDL---VEVFGEEAIPLTRKDLDVTDFESLK-ILKELKPEVIINTAAY 57 +V V GA GQLG +L ++ G E I LT+K +++ D S++ +P++++N+AA+ Sbjct: 3 KVLVTGAGGQLGLELCRQLKQAGYEVIALTKKMMNIADQRSVRHSFGHYQPDIVVNSAAF 62 Query: 58 VRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNP 117 VD E ++A+ +N IGA A + IGA V+ISTDYVF+G +PY E+D +P Sbjct: 63 TSVDQCEKELDKAYLINGIGAYYTALESTRIGAQYVHISTDYVFNGKGTQPYREDDPLDP 122 Query: 118 INVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIV 177 +YG SK +GE R +K IIR + +YG G+ NFVE ++K A +ELR+V Sbjct: 123 KTIYGKSKRLGEELIRLTTKDSTIIRTSWVYGHGGS-----NFVETMLKLAETKQELRVV 177 Query: 178 NDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFEILGWDVRVKPI 237 +DQ SPTYTKD+A + +L P G+YH+ N G CSWYEF AI E G + + + Sbjct: 178 SDQIGSPTYTKDLAEAVIKLFSHPP--GIYHVSNSGICSWYEFATAIMEESGLETAILSV 235 Query: 238 NSSELKRLAKRPKFSALKNEKLEK 261 + E RP +S L + +E+ Sbjct: 236 TTEEYGNKTPRPAYSVLSHRAIEE 259 >pir||S74471 dTDP-6-deoxy-L-mannose-dehydrogenase - Synechocystis sp. (strain PCC 6803) >gi|1651695|dbj|BAA16623.1| (D90899) dTDP-6-deoxy-L-mannose-dehydrogenase [Synechocystis sp.] Length = 280 Score = 179 bits (450), Expect = 3e-44 Identities = 106/275 (38%), Positives = 158/275 (56%), Gaps = 22/275 (8%) Query: 22 EEAIPL---------TRKDLDVTDFESL-KILKELKPEVIINTAAYVRVDDAELYPEEAF 71 E AIPL TR D+ + L + ++ P++I+N+AAY VD AE PE A+ Sbjct: 4 ELAIPLSCFGSVQEATRASFDLAQPDVLGEKIRAFAPDIIVNSAAYTAVDRAETEPELAY 63 Query: 72 KVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNPINVYGASKYIGEIF 131 VNA+ +A++A EIGA V+ISTDYVFDG++ PY E D NP+ VYG SK+ GEI Sbjct: 64 AVNALAPQAIAKVAKEIGAYVVHISTDYVFDGSQSSPYRETDATNPLGVYGQSKFQGEIA 123 Query: 132 TRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIVNDQFMSPTYTKDVA 191 + + I+R A +YG G+ GNFV+ +++ + +++R+V DQ PT+ KD+A Sbjct: 124 IADSGCNFLIVRTAWVYGVHGS----GNFVKTMVRLGKERQKVRVVADQIGGPTWAKDLA 179 Query: 192 RTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIF---EILGWDVRVK---PINSSELKRL 245 + L R G+YH N G SWY+F AIF E LG ++V+ PI ++ Sbjct: 180 EAIAALTEQRAQ-GIYHYSNSGVASWYDFAVAIFEEVENLGIPLKVRQVVPIATAAYPTP 238 Query: 246 AKRPKFSALKNEKL-EKIGLKMKHWKEALGEYLKE 279 A+RP +S L ++K+ E +G HW+ +L L + Sbjct: 239 ARRPAYSVLSHQKIVETLGSAPPHWRASLRAMLHQ 273 >gb|AAC44972.1| (U09239) 32.3 kDa cps19fO gene product [Streptococcus pneumoniae] Length = 283 Score = 176 bits (443), Expect = 2e-43 Identities = 107/287 (37%), Positives = 163/287 (56%), Gaps = 16/287 (5%) Query: 3 VAVIGANGQLGTDL---VEVFGEEAIPLTRKDLDVTDFESL-KILKELKPEVIINTAAYV 58 + + GANGQLGT+L ++ EE + + ++D+TD E + K+ +E+KP ++ + AAY Sbjct: 2 ILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITDAEMVEKVFEEVKPTLVYHCAAYT 61 Query: 59 RVDDAELYPEEA-FKVNAIGALNVARIANEIGAINVYISTDYVFDGAK--GEPYTEEDIP 115 VD AE +E F +N G NVAR + + GA VYISTDYVFDG K G+ + +D P Sbjct: 62 AVDAAEDEGKELDFAINVTGTKNVARASEKHGATLVYISTDYVFDGKKPVGQEWEVDDRP 121 Query: 116 NPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELR 175 +P YG +K +GE + +YIIR A ++G G NFV + A + L Sbjct: 122 DPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGK-----NFVFTMQNLAKTHKTLT 176 Query: 176 IVNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGY--CSWYEFTRAIFEILGWDVR 233 +VNDQ+ PT+T+ +A + L R FG YH+ N+ +WY+F A+ + DV Sbjct: 177 VVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDTTWYDF--AVEILKDTDVE 234 Query: 234 VKPINSSELKRLAKRPKFSALKNEKLEKIGLKMKHWKEALGEYLKEK 280 VKP++SS+ AKRP S + K + G + W++AL E+ K++ Sbjct: 235 VKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQEFYKQE 281 >gb|AAC38675.1| (AF030359) dTDP-L-rhamnose synthase [Streptococcus pneumoniae] >gi|2804698|gb|AAC38685.1| (AF030361) dTDP-L-rhamnose synthase [Streptococcus pneumoniae] >gi|2804717|gb|AAC38701.1| (AF030364) dTDP-L-rhamnose synthase [Streptococcus pneumoniae] >gi|4200436|gb|AAD10184.1| (AF026471) Cps2O [Streptococcus pneumoniae] Length = 283 Score = 175 bits (440), Expect = 4e-43 Identities = 106/287 (36%), Positives = 163/287 (55%), Gaps = 16/287 (5%) Query: 3 VAVIGANGQLGTDL---VEVFGEEAIPLTRKDLDVTDFESL-KILKELKPEVIINTAAYV 58 + + GANGQLGT+L ++ EE + + ++D+TD E + K+ +E+KP ++ + AAY Sbjct: 2 ILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITDAEMVEKVFEEVKPTLVYHCAAYT 61 Query: 59 RVDDAELYPEEA-FKVNAIGALNVARIANEIGAINVYISTDYVFDGAK--GEPYTEEDIP 115 VD AE +E F +N G NVA+ + + GA VYISTDYVFDG K G+ + +D P Sbjct: 62 AVDAAEDEGKELDFAINVTGTKNVAKASEKHGATLVYISTDYVFDGKKPVGQEWEVDDRP 121 Query: 116 NPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELR 175 +P YG +K +GE + +YIIR A ++G G NFV + A + L Sbjct: 122 DPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGK-----NFVFTMQNLAKTHKTLT 176 Query: 176 IVNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGY--CSWYEFTRAIFEILGWDVR 233 +VNDQ+ PT+T+ +A + L R FG YH+ N+ +WY+F A+ + DV Sbjct: 177 VVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDTTWYDF--AVEILKDTDVE 234 Query: 234 VKPINSSELKRLAKRPKFSALKNEKLEKIGLKMKHWKEALGEYLKEK 280 VKP++SS+ AKRP S + K + G + W++AL E+ K++ Sbjct: 235 VKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQEFYKQE 281 >gb|AAC69541.1| (AF057294) Cps23fR [Streptococcus pneumoniae] Length = 283 Score = 175 bits (439), Expect = 6e-43 Identities = 106/287 (36%), Positives = 163/287 (55%), Gaps = 16/287 (5%) Query: 3 VAVIGANGQLGTDL---VEVFGEEAIPLTRKDLDVTDFESL-KILKELKPEVIINTAAYV 58 + + GANGQLGT+L ++ EE + + ++D+TD E + K+ +E+KP ++ + AAY Sbjct: 2 ILITGANGQLGTELRYLLDERNEEYVAVDVVEMDITDAEMVEKVFEEVKPTLVYHCAAYT 61 Query: 59 RVDDAELYPEEA-FKVNAIGALNVARIANEIGAINVYISTDYVFDGAK--GEPYTEEDIP 115 VD AE +E F +N G NVA+ + + GA VYISTDYVFDG K G+ + +D P Sbjct: 62 AVDAAEDEGKELDFAINVTGTKNVAKASEKHGATLVYISTDYVFDGKKPVGQEWEVDDRP 121 Query: 116 NPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELR 175 +P YG +K +GE + +YIIR A ++G G NFV + A + L Sbjct: 122 DPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGK-----NFVFTMQNLAKTHKTLT 176 Query: 176 IVNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGY--CSWYEFTRAIFEILGWDVR 233 +VNDQ+ PT+T+ +A + L R FG YH+ N+ +WY+F A+ + DV Sbjct: 177 VVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDTTWYDF--AVEILKDTDVE 234 Query: 234 VKPINSSELKRLAKRPKFSALKNEKLEKIGLKMKHWKEALGEYLKEK 280 VKP++SS+ AKRP S + K + G + W++AL E+ K++ Sbjct: 235 VKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQEFYKQE 281 >gb|AAC78677.1| (AF094575) dTDP-L-rhamnose synthase Cps19aO [Streptococcus pneumoniae] Length = 283 Score = 175 bits (439), Expect = 6e-43 Identities = 106/287 (36%), Positives = 162/287 (55%), Gaps = 16/287 (5%) Query: 3 VAVIGANGQLGTDL---VEVFGEEAIPLTRKDLDVTDFESL-KILKELKPEVIINTAAYV 58 + + GANGQLGT+L ++ EE + + ++D+TD E + K+ +E+KP ++ + AAY Sbjct: 2 ILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITDAEMVEKVFEEVKPTLVYHCAAYT 61 Query: 59 RVDDAELYPEEA-FKVNAIGALNVARIANEIGAINVYISTDYVFDGAK--GEPYTEEDIP 115 VD AE E F +N G NVA+ + + GA VYISTDYVFDG K G+ + +D P Sbjct: 62 AVDAAEDEGRELDFAINVTGTKNVAKASEKHGATLVYISTDYVFDGKKPVGQEWEVDDRP 121 Query: 116 NPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELR 175 +P YG +K +GE + +YIIR A ++G G NFV + A + L Sbjct: 122 DPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGK-----NFVFTMQNLAKTHKTLT 176 Query: 176 IVNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGY--CSWYEFTRAIFEILGWDVR 233 +VNDQ+ PT+T+ +A + L R FG YH+ N+ +WY+F A+ + DV Sbjct: 177 VVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDTTWYDF--AVEILKDTDVE 234 Query: 234 VKPINSSELKRLAKRPKFSALKNEKLEKIGLKMKHWKEALGEYLKEK 280 VKP++SS+ AKRP S + K + G + W++AL E+ K++ Sbjct: 235 VKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQEFYKQE 281 >gb|AAC38691.1| (AF030362) dTDP-L-rhamnose synthase [Streptococcus pneumoniae] >gi|2804711|gb|AAC38696.1| (AF030363) dTDP-L-rhamnose synthase [Streptococcus pneumoniae] >gi|2804724|gb|AAC38707.1| (AF030365) dTDP-L-rhamnose synthase [Streptococcus pneumoniae] >gi|2804730|gb|AAC38712.1| (AF030366) dTDP-L-rhamnose synthase [Streptococcus pneumoniae] >gi|3320402|gb|AAC38760.1| (AF030373) dTDP-L-rhamnose synthase [Streptococcus pneumoniae] Length = 283 Score = 174 bits (437), Expect = 1e-42 Identities = 106/287 (36%), Positives = 163/287 (55%), Gaps = 16/287 (5%) Query: 3 VAVIGANGQLGTDL---VEVFGEEAIPLTRKDLDVTDFESL-KILKELKPEVIINTAAYV 58 + + GANGQLGT+L ++ EE + + ++D+T+ E + K+ +E+KP ++ + AAY Sbjct: 2 ILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITNEEMVEKVFEEVKPTLVYHCAAYT 61 Query: 59 RVDDAELYPEEA-FKVNAIGALNVARIANEIGAINVYISTDYVFDGAK--GEPYTEEDIP 115 VD AE +E F +N G NVAR + + GA VYISTDYVFDG K G+ + +D P Sbjct: 62 AVDAAEDEGKELDFAINVTGTKNVARASEKHGATLVYISTDYVFDGKKPVGQEWEVDDRP 121 Query: 116 NPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELR 175 +P YG +K +GE + +YIIR A ++G G NFV + A + L Sbjct: 122 DPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGK-----NFVFTMQNLAKTHKTLT 176 Query: 176 IVNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGY--CSWYEFTRAIFEILGWDVR 233 +VNDQ+ PT+T+ +A + L R FG YH+ N+ +WY+F A+ + DV Sbjct: 177 VVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDTTWYDF--AVEILKDTDVE 234 Query: 234 VKPINSSELKRLAKRPKFSALKNEKLEKIGLKMKHWKEALGEYLKEK 280 VKP++SS+ AKRP S + K + G + W++AL E+ K++ Sbjct: 235 VKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQEFYKQE 281 >gb|AAC38680.1| (AF030360) dTDP-L-rhamnose synthase [Streptococcus pneumoniae] Length = 283 Score = 174 bits (436), Expect = 1e-42 Identities = 105/287 (36%), Positives = 162/287 (55%), Gaps = 16/287 (5%) Query: 3 VAVIGANGQLGTDL---VEVFGEEAIPLTRKDLDVTDFESL-KILKELKPEVIINTAAYV 58 + + G NGQLGT+L ++ EE + + ++D+TD E + K+ +E+KP ++ + AAY Sbjct: 2 ILITGTNGQLGTELRYLLDERNEEYVAVDVAEMDITDAEMVEKVFEEVKPTLVYHCAAYT 61 Query: 59 RVDDAELYPEEA-FKVNAIGALNVARIANEIGAINVYISTDYVFDGAK--GEPYTEEDIP 115 VD AE +E F +N G NVA+ + + GA VYISTDYVFDG K G+ + +D P Sbjct: 62 AVDAAEDEGKELDFAINVTGTKNVAKASEKHGATLVYISTDYVFDGKKPVGQEWEVDDRP 121 Query: 116 NPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELR 175 +P YG +K +GE + +YIIR A ++G G NFV + A + L Sbjct: 122 DPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGK-----NFVFTMQNLAKTHKTLT 176 Query: 176 IVNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGY--CSWYEFTRAIFEILGWDVR 233 +VNDQ+ PT+T+ +A + L R FG YH+ N+ +WY+F A+ + DV Sbjct: 177 VVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDTTWYDF--AVEILKDTDVE 234 Query: 234 VKPINSSELKRLAKRPKFSALKNEKLEKIGLKMKHWKEALGEYLKEK 280 VKP++SS+ AKRP S + K + G + W++AL E+ K++ Sbjct: 235 VKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQEFYKQE 281 >emb|CAB65207.1| (AJ007311) RmlD protein [Legionella pneumophila] Length = 294 Score = 172 bits (431), Expect = 5e-42 Identities = 108/293 (36%), Positives = 162/293 (54%), Gaps = 21/293 (7%) Query: 1 MRVAVIGANGQLGTDLVEVFGE---EAIPLTRKDLDVTDFESLK-ILKELKPEVIINTAA 56 M++ V GANGQ+GT++++ F E TR LD + E + +L E+KP++IIN AA Sbjct: 1 MKILVTGANGQVGTEIIKRFSSSEHEVYACTRDILDCSKLERVHDVLSEIKPDLIINAAA 60 Query: 57 YVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPN 116 Y VD AE P+ A VNA + +++STDYVFDG K Y E DIP+ Sbjct: 61 YTAVDKAEDEPDLAHIVNAEFVCRLVNYCTLKNVPLIHLSTDYVFDGEKEGAYHETDIPH 120 Query: 117 PINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRI 176 P++ YG +K+ GE + KKY I+RV+ ++G+ +G NFV+ ++ A+ +EL I Sbjct: 121 PVSTYGRTKWEGEQAILSQLKKYIILRVSWVFGE-----QGKNFVKTILNLASSRKELNI 175 Query: 177 VNDQFMSPTYTKDVARTLRELL-RLRPS----FGVYHMVNEGYCSWYEFTRAIF------ 225 V+DQ PT +D+AR L E++ ++R S +G+YH +G +W+EF Sbjct: 176 VSDQSGRPTSARDIARVLFEIVQKIRHSSFDYWGLYHYAGQGVTNWHEFANVFLNMAKEK 235 Query: 226 EILGWDVRVKPINSSELKRLAKRPKFSALKNEKLEKI-GLKMKHWKEALGEYL 277 ++L + PI S E A RPK S L K+E I G+K WK L + + Sbjct: 236 QLLLTLTDLNPIKSQEYPTRATRPKNSVLDTTKIETILGIKSCSWKNDLPDVI 288 >pir||G72588 probable dTDP-4-dehydrorhamnose reductase APE1179 - Aeropyrum pernix (strain K1) >gi|5104851|dbj|BAA80165.1| (AP000061) 305aa long hypothetical dTDP-4-dehydrorhamnose reductase [Aeropyrum pernix] Length = 305 Score = 168 bits (422), Expect = 5e-41 Identities = 108/298 (36%), Positives = 172/298 (57%), Gaps = 28/298 (9%) Query: 1 MRVAVIGANGQLGTDLVEVF---GEEAIPLTRKD------------LDVTDFESL-KILK 44 +++ V G G LG +LV+ G P K+ +++ D L ++ + Sbjct: 6 LKLLVTGGTGLLGYNLVQQLLKKGYSVYPTYNKNTPFKLAGARWSKVNLEDPSQLTQLFR 65 Query: 45 ELKPEVIINTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGA 104 ++KP+ +I+TAAY VD EL+ E A+++N + ++ VAR+A G++ +Y+STDYVFDG Sbjct: 66 DIKPDAVIHTAAYTDVDGCELHRERAYRINFLASMTVARLAARHGSLLIYVSTDYVFDGD 125 Query: 105 KGEPYTEEDIPNPINVYGASKYIGEIFTRNYSKK--YYIIRVASLYG--KAGARGKGGNF 160 KG Y EE+ PNPIN YG SK +GE+ T + K ++RV+ LYG G R G N Sbjct: 126 KG-MYREEEAPNPINYYGLSKLLGEVATLSAMDKENVLVVRVSGLYGYSPTGKRNFGIN- 183 Query: 161 VEWVIKKANKGEELRIVNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEF 220 V++K +GEE+R DQ++SPTYT ++R L ++L R GV H+ E S EF Sbjct: 184 ---VLEKLLRGEEVRAFYDQYLSPTYTYFLSRRLIDVLE-REIRGVLHLAGE-RLSRLEF 238 Query: 221 TRAIFEILGWDVR-VKPINSSELKRLAKRPKFSALKNEKLEKIGLKMKHWKEALGEYL 277 + I ++LG D +KPI+ E A+RP+ S+L +K+GL++ +E++ ++ Sbjct: 239 AQLIAKVLGADAELIKPISMKEANLPARRPRDSSLDTTMAKKLGLELPSQEESVKHFV 296 >gb|AAD19916.1| (AF105113) dTDP-L-rhamnose synthase [Streptococcus pneumoniae] Length = 284 Score = 168 bits (420), Expect = 9e-41 Identities = 102/287 (35%), Positives = 161/287 (55%), Gaps = 16/287 (5%) Query: 3 VAVIGANGQLGTDLVEVFGEEAIPLTRKD---LDVTDFESL-KILKELKPEVIINTAAYV 58 + + GANGQLGT+L + E + D +D+T+ E + K+ E+KP ++ + AAY Sbjct: 2 ILITGANGQLGTELRYLLNERNVDYVAVDVTEMDITNSEMVEKVFAEVKPTLVYHCAAYT 61 Query: 59 RVDDAELYPEEA-FKVNAIGALNVARIANEIGAINVYISTDYVFDGAK--GEPYTEEDIP 115 VD AE +E F +N G NVA+ + + GAI VYISTDYVFDG K G+ + +DIP Sbjct: 62 AVDAAEDEGKELDFAINVTGTENVAKGSEKYGAILVYISTDYVFDGKKPVGQEWEVDDIP 121 Query: 116 NPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELR 175 +P YG +K +GE N + ++YIIR A ++G G NFV + A + L Sbjct: 122 DPQTEYGRTKRMGEELVENLTSQHYIIRTAWVFGNYGR-----NFVFTMQSLAETHKTLT 176 Query: 176 IVNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGY--CSWYEFTRAIFEILGWDVR 233 +V+DQ+ PT+T+ +A + + + +G YH+ N+ +WY+F I + DV Sbjct: 177 VVSDQYGRPTWTRTLAEFMTYVTENQKEYGYYHLSNDAAEDTTWYDFASEILK--ESDVE 234 Query: 234 VKPINSSELKRLAKRPKFSALKNEKLEKIGLKMKHWKEALGEYLKEK 280 + P++SS+ AKRP S + K + G + W++AL E+ K++ Sbjct: 235 LLPVDSSKFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALKEFYKQE 281 >gb|AAG29801.1| (AF235050) dTDP-4-keto-6-deoxyhexose reductase [Streptomyces rishiriensis] Length = 288 Score = 163 bits (409), Expect = 2e-39 Identities = 100/279 (35%), Positives = 152/279 (53%), Gaps = 13/279 (4%) Query: 2 RVAVIGANGQLGTDLV---EVFGEEAIPLTRKDLDVTDFESLK-ILKELKPEVIINTAAY 57 R V GA G LG DLV E E + TR+DLD+TD S++ ++ +P I+N AA+ Sbjct: 4 RWLVTGAGGMLGRDLVRVLEALNEPVLAATRQDLDITDRFSVRAVVSRYRPTAIVNCAAW 63 Query: 58 VRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNP 117 R +AE EA +N GA +A I + V++STDYVFDGA PY E P Sbjct: 64 TRFHEAETSEAEAHLINGRGARELATICGDRSIRLVHLSTDYVFDGASRRPYAESAATGP 123 Query: 118 INVYGASKYIGE-IFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRI 176 IN YG +K GE I+R A LYG+ G NF+ +++ + + + Sbjct: 124 INAYGRTKLAGEQAVLELLPDDGTIVRTAWLYGRHGT-----NFLRKMVRLEQTHKTVDV 178 Query: 177 VNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFEILGWDV-RVK 235 V+DQ+ PT++ D+A+ + L+R S GV+H + G +WY+F R IF +LG D R++ Sbjct: 179 VDDQWGQPTWSVDLAQQIVALVRHGAS-GVFHGTSSGETTWYDFARMIFRLLGADPGRIR 237 Query: 236 PINSSELKRLAKRPKFSALKNEKLEKIGL-KMKHWKEAL 273 P+ S ++ RP+++ L + ++GL ++HW AL Sbjct: 238 PVRSDQIAGGELRPRYTVLGHAAWREVGLTPIRHWSAAL 276 >dbj|BAA21509.1| (AB000631) dTDP-4-keto-L-rhamnose reductase [Streptococcus mutans] Length = 284 Score = 162 bits (407), Expect = 3e-39 Identities = 99/286 (34%), Positives = 155/286 (53%), Gaps = 16/286 (5%) Query: 3 VAVIGANGQLGTDLVEVFGE---EAIPLTRKDLDVTDFESL-KILKELKPEVIINTAAYV 58 + + G+NGQLGT+L + E + + + ++D+T E + ++ ++KP ++ + AAY Sbjct: 2 ILITGSNGQLGTELRHLLNERNEDYVAVDVAEMDITKAEKVDEVFLQVKPSLVYHCAAYT 61 Query: 59 RVDDAELYPEEA-FKVNAIGALNVARIANEIGAINVYISTDYVFDGAK--GEPYTEEDIP 115 VD AE +E + +N G N+A+ + A VYISTDYVFDG K G+ + +D P Sbjct: 62 AVDAAEDEGKELDYAINVTGTENIAKACEKYNATLVYISTDYVFDGEKPVGQEWEVDDKP 121 Query: 116 NPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELR 175 +P YG +K +GE Y K +YIIR A ++G G NFV + A L Sbjct: 122 DPKTEYGRTKRLGEEAVEKYVKNFYIIRTAWVFGNYGK-----NFVFTMQHLAKSHNSLT 176 Query: 176 IVNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGY--CSWYEFTRAIFEILGWDVR 233 +VNDQ PT+T+ +A + L + +G YH+ N+ +WY+F I + DV Sbjct: 177 VVNDQHGRPTWTRTLAEFMTYLAENQKEYGYYHLSNDATEDTTWYDFALEILK--DTDVV 234 Query: 234 VKPINSSELKRLAKRPKFSALKNEKLEKIGLKMKHWKEALGEYLKE 279 VKP++SS+ AKRP S + K + G + W+EAL E+ K+ Sbjct: 235 VKPVDSSQFPAKAKRPLNSTMSLTKAKATGFVIPTWQEALQEFYKQ 280 >gb|AAD05457.1| (AF064070) putative dTDP-4-keto-L-rhamnose reductase [Burkholderia pseudomallei] Length = 298 Score = 161 bits (403), Expect = 9e-39 Identities = 106/297 (35%), Positives = 158/297 (52%), Gaps = 31/297 (10%) Query: 1 MRVAVIGANGQLGTDLVE---VFGEEAIPLTRKDLDVTDFESL-KILKELKPEVIINTAA 56 M++ V GANGQ+G +L V G+ +PLTR+ D+ E+L +I+++ KP+V++N AA Sbjct: 1 MKILVTGANGQVGWELARSLAVLGQ-VVPLTREQADLGRPETLARIVEDAKPDVVVNAAA 59 Query: 57 YVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPN 116 Y VD AE A +N +A +G + V+ STDYVFDG K PY E D Sbjct: 60 YTAVDAAETDGAAANVINGEAVGVLAAATKRVGGLFVHYSTDYVFDGTKPSPYIETDPTC 119 Query: 117 PINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRI 176 P+N YGASK +GE+ + R ++ ARGK NF+ +++ A + EE++I Sbjct: 120 PVNAYGASKLLGELAVAETGGDWLTFRTTWVF---AARGK--NFLRTMLRLAKEREEMKI 174 Query: 177 VNDQFMSPTYTKDVA--------RTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFEIL 228 V DQF +PT+ + +A +RE + GVYHM + G SW+ F AI I Sbjct: 175 VADQFGAPTWARSIADGTAHALTTAMRERAAGAFTSGVYHMTSAGQTSWHGFADAI--IA 232 Query: 229 GWDV----------RVKPINSSELKRLAKRPKFSALKNEKL-EKIGLKMKHWKEALG 274 W R+ PI +S A+RP S L N+ L E+ G+++ W+ A+G Sbjct: 233 SWRAAPGAAPLAVSRIVPIPASAYPVPAQRPANSVLSNKALKERFGIELPDWRYAVG 289 >emb|CAA07388.1| (AJ006985) StrL [Streptomyces glaucescens] Length = 305 Score = 158 bits (395), Expect = 8e-38 Identities = 108/286 (37%), Positives = 143/286 (49%), Gaps = 17/286 (5%) Query: 2 RVAVIGANGQLGTDLVEVFGEEAIPLT----RKDLDVTDFESLK-ILKELKPEVIINTAA 56 R V GA+G LG +L +P+ R DLDVTD + + +L +P V++N AA Sbjct: 8 RWLVTGASGMLGRELTARLSRRGVPVVPLVRRADLDVTDPAAARALLARHRPAVLVNCAA 67 Query: 57 YVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPN 116 + VD AE + A VN G ++AR G + +STDYVF G PY E+D P Sbjct: 68 WTAVDAAEAHEARALAVNGEGPGHLARACRATGTRMIQLSTDYVFAGLADRPYREDDPPA 127 Query: 117 PINVYGASKYIGE-IFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELR 175 P YG +K GE Y++R A LYG GA NFV +I+ A + Sbjct: 128 PRTAYGRTKLAGERAVLDTLPDGGYVVRTAWLYGSGGA-----NFVSTMIRLAAAEGTVP 182 Query: 176 IVNDQFMSPTYTKDVARTLREL----LRLRPSFGVYHMVNEGYCSWYEFTRAIFEILGWD 231 +V+DQ PT+T D+A L L LR GVYH VN G +W+ R IF G D Sbjct: 183 VVDDQHGGPTWTGDLADRLLALGAAALRGTAPPGVYHAVNAGSTTWHALAREIFRRAGAD 242 Query: 232 V-RVKPINSSELKRLAKRPKFSALKNEKLEKIGL-KMKHWKEALGE 275 RV+PI S EL R A RP +S L + GL ++ W+ AL E Sbjct: 243 PGRVRPIGSGELARPAARPPYSVLAQGRWRAAGLAPLRDWRAALAE 288 >pir||T31087 probable dTDP-L-rhamnose synthase - Serratia marcescens >gi|2662408|gb|AAC00179.1| (AF038816) putative dTDP-L-rhamnose synthase [Serratia marcescens] Length = 288 Score = 157 bits (394), Expect = 1e-37 Identities = 99/283 (34%), Positives = 151/283 (52%), Gaps = 15/283 (5%) Query: 1 MRVAVIGANGQLGTDLVEVFGEE--AIPLTRKDLDVTDFESLKI-LKELKPEVIINTAAY 57 MRV + GA GQLG +++ F + + + LD+ D ++ +++L P+ IIN AAY Sbjct: 1 MRVLLTGAAGQLGRCIIDRFPANWTLVAMDSQQLDIADSAAVSATVEQLVPDAIINAAAY 60 Query: 58 VRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNP 117 VD AE PE+A +NA G +A A ++ ++ISTDYVFDG EPY EE +P Sbjct: 61 TAVDKAESEPEKARAINAFGPGFLAAAAAKLDIPFIHISTDYVFDGTSSEPYCEETPCSP 120 Query: 118 INVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIV 177 +VYG +K GE+ + K +IR A ++ + G NFV+ +++ + EL +V Sbjct: 121 KSVYGQTKLEGELAALQANPKTVVIRTAWVFSE-----YGNNFVKTMLRVGAQRGELGVV 175 Query: 178 NDQFMSPTYTKDVARTLRELL-RLRPSFGVYHMVNEGYCSWYEFTRAIFEILGWDVR--- 233 +DQ PTY D+A T+ +L + +G+YH + SW++F AIF R Sbjct: 176 SDQLGCPTYAGDIAATVIAMLSHPQLPYGIYHYCGDNAVSWFDFGCAIFREAETSTRYPH 235 Query: 234 ---VKPINSSELKRLAKRPKFSALKNEKLEKIGLKMKHWKEAL 273 VKPI + E A RP +S L K+ + LK W++ L Sbjct: 236 KVSVKPIATHEYPTPASRPAYSILSTSKICALALKPSPWEQQL 278 >sp|P55463|RFBD_RHISN PROBABLE DTDP-4-DEHYDRORHAMNOSE REDUCTASE (DTDP-4-KETO-L-RHAMNOSE REDUCTASE) (DTDP-6-DEOXY-L-MANNOSE DEHYDROGENASE) (DTDP-L-RHAMNOSE SYNTHETASE) >gi|2182409|gb|AAB91681.1| (AE000074) Y4gG [Rhizobium sp. NGR234] Length = 296 Score = 155 bits (389), Expect = 4e-37 Identities = 98/286 (34%), Positives = 155/286 (53%), Gaps = 19/286 (6%) Query: 1 MRVAVIGANGQLGTDLVEVFGE--EAIPLTRKDLDVTDFESL-KILKELKPEVIINTAAY 57 MR+AV G NGQ+ L E + L R + D+ ++ +++ P++I++ AAY Sbjct: 1 MRLAVTGKNGQIALALKAQARPDVEILTLGRPNFDLACRSTVASSIRDAAPDIIVSLAAY 60 Query: 58 VRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNP 117 VD AE P EAF VN G +A A +G +++STDYVFDGAK PY EED P Sbjct: 61 TAVDKAESEPYEAFAVNRDGVQALAEAAAGLGVPVIHLSTDYVFDGAKPVPYCEEDRTGP 120 Query: 118 INVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIV 177 I+VYG SK GE + + + I+R + +Y + G NFV+ +++ A+ +EL +V Sbjct: 121 ISVYGRSKLEGEFAVASANPNHTILRTSWVYSRYGQ-----NFVKKMLRLADTNDELNVV 175 Query: 178 NDQFMSPTYTKDVARTLRELLRLRPSF------GVYHMVNEGYCSWYEFTRAIF----EI 227 DQ PT D++ + + R S G++H+ G SW F + +F EI Sbjct: 176 ADQLGCPTSADDISVAVMTIARRMLSSSSADLRGIFHLSGSGEASWAAFAKYVFSVYDEI 235 Query: 228 LGWDVRVKPINSSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEA 272 G ++V I+++E A+RP S L +KLE+ G+++ +W+E+ Sbjct: 236 TGRQIKVHDISAAEYPTPARRPANSRLHCDKLERTFGIRLPNWEES 281 >gb|AAF67512.1|AF170880_19 (AF170880) NovS [Streptomyces spheroides] Length = 288 Score = 155 bits (388), Expect = 5e-37 Identities = 98/279 (35%), Positives = 150/279 (53%), Gaps = 13/279 (4%) Query: 2 RVAVIGANGQLGTDLVEVF---GEEAIPLTRKDLDVTDFESLK-ILKELKPEVIINTAAY 57 R V GA G LG DLV + E + +TR DLD+TD S++ ++ +P I+N AA+ Sbjct: 4 RWLVTGAAGMLGRDLVALLRGLNEPVVAITRHDLDITDRLSVRAVVDRHRPTTIVNCAAW 63 Query: 58 VRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNP 117 R +AE A VN GA +A + + V++STDYVFDG PY E + +P Sbjct: 64 TRFGEAEAGESAALLVNGGGARELAAVCRDRSIRLVHLSTDYVFDGTSRRPYAESAVTSP 123 Query: 118 INVYGASKYIGEIFTRN-YSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRI 176 IN YG +K GE + I+R A LYG+ G NF+ +++ E + + Sbjct: 124 INAYGRTKQAGEQAVLDLLPDDGTIVRTAWLYGRHGM-----NFIRKMVRLEQLRETVDV 178 Query: 177 VNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFEILGWDV-RVK 235 V+DQ+ PT+T D+A+ + L+R S GV+H + G +WY+ R F +LG D RV+ Sbjct: 179 VDDQWGQPTWTVDLAQQIVALVRHGAS-GVFHGTSAGEATWYDLARMTFRLLGADPGRVR 237 Query: 236 PINSSELKRLAKRPKFSALKNEKLEKIGL-KMKHWKEAL 273 P+ S + RP+++ L ++ + GL ++HW AL Sbjct: 238 PVPSDRIAGGELRPRYTVLGHDAWREAGLTPIRHWTTAL 276 >pir||T00104 probable dTDP-4-dehydrorhamnose reductase (EC 1.1.1.133) - Actinobacillus actinomycetemcomitans >gi|3132256|dbj|BAA28133.1| (AB010415) dTDP-4-keto-L-rhamnose reductase [Actinobacillus actinomycetemcomitans] Length = 294 Score = 153 bits (383), Expect = 2e-36 Identities = 101/289 (34%), Positives = 149/289 (50%), Gaps = 22/289 (7%) Query: 2 RVAVIGANGQLGTDLVEVFGE----EAIPLTRKDLDVTDFESL-KILKELKPEVIINTAA 56 R+ + GA GQLG L ++ + E + L +LD+T+ + + I+ KP VIIN AA Sbjct: 3 RLLITGAGGQLGRSLAKLLVDNGRYEVLALDFSELDITNKDMVFSIIDSFKPNVIINAAA 62 Query: 57 YVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPN 116 Y VD AEL A+ VN G +A A + +++STDYVFDG K Y E DI + Sbjct: 63 YTSVDQAELEVSSAYSVNVRGVQYLAEAAIRHNSAILHVSTDYVFDGYKSGKYKETDIIH 122 Query: 117 PINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRI 176 P+ VYG SK GE S K I+R + +G+ G NFV+ +++ A + L + Sbjct: 123 PLCVYGKSKAEGERLLLTLSPKSIILRTSWTFGE-----YGNNFVKTMLRLAKNRDILGV 177 Query: 177 VNDQFMSPTYTKDVARTLRELLRL-----RPSFGVYHMVNEGYCSWYEFTRAIFE----- 226 V DQ PTY+ D+A L ++ +G+YH E SWY+F AIF+ Sbjct: 178 VADQIGGPTYSGDIASVLIQIAEKIIVGETVKYGIYHFTGEPCVSWYDFAIAIFDEAVAQ 237 Query: 227 -ILGWDVRVKPINSSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEAL 273 +L V I +++ LAKRP S L K+++ G++ W+ AL Sbjct: 238 KVLENVPLVNAITTADYPTLAKRPANSCLDLTKIQQAFGIQPSDWQRAL 286 >pir||C81164 dTDP-L-rhamnose synthase, probable NMB0756 [imported] - Neisseria meningitidis (group B strain MD58) >gi|7225985|gb|AAF41169.1| (AE002429) dTDP-L-rhamnose synthase, putative [Neisseria meningitidis MC58] Length = 306 Score = 153 bits (383), Expect = 2e-36 Identities = 99/284 (34%), Positives = 143/284 (49%), Gaps = 16/284 (5%) Query: 1 MRVAVIGANGQLGTDLVEVFGE--EAIPLTRKDLDVTDFESL-KILKELKPEVIINTAAY 57 MR+ + G+ QL L + E E I LD+TD +++ ++K +P+ I+NTAAY Sbjct: 1 MRILLTGSKSQLARCLRDRLPEDWETIATDSASLDITDADAVCNMVKSFQPDAIVNTAAY 60 Query: 58 VRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNP 117 VD AE AF VNA N+A A+ A ++ISTDYVFDG PY E D NP Sbjct: 61 TAVDKAEGDAAAAFAVNASAVYNLALAAHRAHARFIHISTDYVFDGKGKRPYQESDFTNP 120 Query: 118 INVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIV 177 NVYG SK GE+ + + I+R + L+ + G NF+ ++ A + L V Sbjct: 121 SNVYGQSKTAGELLALSANPDSLILRTSWLFSE-----YGDNFIRTMLNLARERSPLSAV 175 Query: 178 NDQFMSPTYTKDVARTLRELLR-LRPSFGVYHMVNEGYCSWYEFTRAIFEILGWDVRVKP 236 ++Q PTY D++ T+ LL+ P G+YH SWYEF + IF+ P Sbjct: 176 HNQIGCPTYAGDLSATIIRLLQHSNPVRGIYHYAGSKSVSWYEFAQHIFQAASQQQTSFP 235 Query: 237 ------INSSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEAL 273 ++ E A RP +S L K+E G+K W++AL Sbjct: 236 VPELTAVSDKEYPTAAPRPAYSILDCRKIENDFGIKPSDWQKAL 279 >sp|P29781|STRL_STRGR DTDP-4-DEHYDRORHAMNOSE REDUCTASE (DTDP-4-KETO-L-RHAMNOSE REDUCTASE) (DTDP-6-DEOXY-L-MANNOSE DEHYDROGENASE) (DTDP-L-RHAMNOSE SYNTHETASE) >gi|68281|pir||SYSMPG dTDP-dihydrostreptose synthase - Streptomyces griseus >gi|49013|emb|CAA44443.1| (X62567) dTDP-dihydrostreptose synthase [Streptomyces griseus] Length = 304 Score = 152 bits (381), Expect = 4e-36 Identities = 102/285 (35%), Positives = 146/285 (50%), Gaps = 16/285 (5%) Query: 2 RVAVIGANGQLGTDLVEVF---GEEAIPLTRKDLDVTDFESLK-ILKELKPEVIINTAAY 57 R V GA+G LG +L + G L R LD+TD +++ + E +P V++N AA+ Sbjct: 8 RWLVTGASGMLGRELTPLLDRRGAAVTALGRGHLDITDGAAVRSAVAEHRPAVVVNCAAW 67 Query: 58 VRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNP 117 VD+AE P A VN G ++A+ +GA+ + +STDYVF G+ G PY E+ P Sbjct: 68 TAVDEAESEPALAMAVNGEGPRHLAQACRAVGAVLLQLSTDYVFPGSGGRPYREDHPTGP 127 Query: 118 INVYGASKYIGE-IFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRI 176 VYG +K GE YI+R A LYG G NFV +I+ + + + Sbjct: 128 RTVYGCTKRAGERAVLEVLPDTGYIVRTAWLYGAGGP-----NFVAKMIRLEADEDTVLV 182 Query: 177 VNDQFMSPTYTKDVARTLREL----LRLRPSFGVYHMVNEGYCSWYEFTRAIFEILGWD- 231 V+DQ PT+T D+A L L L G+YH N G +W F +LG D Sbjct: 183 VDDQHGQPTWTADLADRLAALGAAALAGTAPAGIYHATNTGGTTWNALAPETFRLLGADP 242 Query: 232 VRVKPINSSELKRLAKRPKFSALKNEKLEKIGLK-MKHWKEALGE 275 RV+P S L R A RP++S L + + GL+ ++HW+ AL E Sbjct: 243 ARVRPTTSLALARPAVRPRYSVLDQSRWKAAGLEPLRHWRAALTE 287 >pir||F81943 probable dTDP-4-dehydrorhamnose reductase (EC 1.1.1.133) NMA0967 [imported] - Neisseria meningitidis (group A strain Z2491) >gi|7379670|emb|CAB84237.1| (AL162754) putative dTDP-4-dehydrorhamnose reductase [Neisseria meningitidis Z2491] Length = 287 Score = 151 bits (378), Expect = 8e-36 Identities = 99/290 (34%), Positives = 145/290 (49%), Gaps = 16/290 (5%) Query: 1 MRVAVIGANGQLGTDLVEVFGE--EAIPLTRKDLDVTDFESL-KILKELKPEVIINTAAY 57 MR+ + G+ QL L + E E I LD+TD +++ ++K +P+ I+NTAAY Sbjct: 1 MRILLTGSKSQLARCLRDRLPEDWETIATDSASLDITDADAVCNMVKSFQPDAIVNTAAY 60 Query: 58 VRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNP 117 VD AE AF VNA N+A A+ A ++ISTDY+FDG PY E D NP Sbjct: 61 TAVDKAEGDAAAAFAVNASAVYNLALAAHRAHARFIHISTDYIFDGKGKRPYQESDFTNP 120 Query: 118 INVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIV 177 NVYG SK GE+ + + I+R + L+ + G NFV ++ A + L V Sbjct: 121 SNVYGQSKTAGELLALSANPDSLILRTSWLFSE-----YGDNFVRTMLNLARERSPLSAV 175 Query: 178 NDQFMSPTYTKDV-ARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFEILGWDVRVKP 236 ++Q PTY D+ A +R L + P G+YH V SWYEF + IF+ P Sbjct: 176 HNQIGCPTYAGDLSAAIIRLLQQSNPVRGIYHYVGGKSVSWYEFAQHIFQAASQQQTSFP 235 Query: 237 ------INSSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEALGEYLKE 279 ++ E A RP +S L K+E +K W++AL + + + Sbjct: 236 VPELTAVSDKEYPTAAPRPAYSILDCRKIENDFSIKPSDWQKALAQVVSK 285 >gb|AAA68212.1| (L37354) thymidine diphospho-4-keto-6-deoxyglucose 3, 5-epimerase [Saccharopolyspora erythraea] Length = 307 Score = 148 bits (369), Expect = 9e-35 Identities = 102/294 (34%), Positives = 147/294 (49%), Gaps = 27/294 (9%) Query: 1 MRVAVIGANGQLGTDLVEVFGEEAIPLTRK----DLDVTDFESLKIL----------KEL 46 + V V G GQ+G++L + + L +LDVTD E++ +L Sbjct: 6 LAVLVPGGRGQVGSELRRIVSGWSGALVHAPGSGELDVTDAEAVADAVDSFAETARDSDL 65 Query: 47 KPEVIINTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKG 106 +P V++N AAY VD AE P+ + +N GA +A G ++ISTDYVF G Sbjct: 66 RP-VVVNAAAYTAVDAAEEEPDRSAAINVAGAAALADACGRRGVPLLHISTDYVFPGDAT 124 Query: 107 EPYTEEDIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIK 166 PY +D P YG +K GE + + +++R A +YG G NFV+ + + Sbjct: 125 RPYEPDDETGPRTSYGRTKLDGERAVLDSGARAWVVRTAWVYGAGGK-----NFVKTMAR 179 Query: 167 KANKGEELRIVNDQFMSPTYTKDVARTLRELL-----RLRPSFGVYHMVNEGYCSWYEFT 221 ++ + L +V+DQ PT+ D+A L EL R P V H VN G SW+EF Sbjct: 180 LESERDTLSVVDDQVGCPTWAADLAAGLLELAGRVAERKGPEQRVLHCVNGGQSSWFEFA 239 Query: 222 RAIFEILGWD-VRVKPINSSELKRLAKRPKFSALKNEKLEKIGL-KMKHWKEAL 273 RA+F LG D RV+P +S E A RP +S L E GL ++HW+EAL Sbjct: 240 RAVFAELGADPERVRPCSSEEFPLPAPRPAYSVLSGRAWEASGLTPLRHWREAL 293 >pir||C83000 dTDP-4-dehydrorhamnose reductase PA5162 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9951464|gb|AAG08547.1|AE004929_2 (AE004929) dTDP-4-dehydrorhamnose reductase [Pseudomonas aeruginosa] Length = 302 Score = 148 bits (369), Expect = 9e-35 Identities = 100/298 (33%), Positives = 157/298 (52%), Gaps = 25/298 (8%) Query: 2 RVAVIGANGQLGTDLVEVFGE--EAIPLTRKDLDVTDFESL-KILKELKPEVIINTAAYV 58 R+ ++GANGQ+G +L E + R+ D+ D E L ++++ +P+ I+N AY Sbjct: 3 RILLLGANGQVGWELQRALAPLGELLVCDRRRADLADPEGLARLVRAERPQFIVNAGAYT 62 Query: 59 RVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNPI 118 VD AE + A +NA +A A GA V+ STDYVFDGA P+ E+ P+ Sbjct: 63 AVDKAESDADNARLINARAVAVLAEEAAACGAWLVHYSTDYVFDGAGSVPFAEDAPTGPL 122 Query: 119 NVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIVN 178 +VYG +K GE R ++ I R + +Y +GGNF + +++ A + +EL++V Sbjct: 123 SVYGQTKLEGEQAIRASGCRHLIFRTSWVYA-----ARGGNFAKTMLRLAGQRDELKVVA 177 Query: 179 DQFMSPTYTKDVAR-TLRELLRL-------RPSFGVYHMVNEGYCSWYEFTRAIFEIL-- 228 DQF +PT + +A T + L RL + G YH+V G SW+ + R + E Sbjct: 178 DQFGAPTSAELIADVTAQALQRLCWDVELAARASGTYHLVASGETSWHLYARFVIEQALE 237 Query: 229 -GWDV-----RVKPINSSELKRLAKRPKFSALKNEKLEKI-GLKMKHWKEALGEYLKE 279 GW++ RV PI + + AKRP S L N KL+++ GL + W+ G ++E Sbjct: 238 RGWELQATPQRVLPIATEDYPVPAKRPANSRLDNRKLQQVFGLVLPDWRYHAGRMIQE 295 >dbj|BAA82534.1| (AB030032) dTDP-4-keto-L-rhamnose reductase [Actinobacillus actinomycetemcomitans] Length = 292 Score = 146 bits (364), Expect = 3e-34 Identities = 92/284 (32%), Positives = 149/284 (52%), Gaps = 20/284 (7%) Query: 5 VIGANGQLGTDLVEVFG--EEAIPLTRKDLDVTDFESLK-ILKELKPEVIINTAAYVRVD 61 + GANGQ+G L + E + + +LD+T+ ++K +K +P+V+IN AA+ VD Sbjct: 6 ITGANGQVGHCLTQQLQGKHEILAVDHDELDITNQSAVKKTVKNFRPDVVINAAAHTAVD 65 Query: 62 DAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNPINVY 121 AE E + +N G +A A +GA ++ISTDYVFDG + Y E D +P ++Y Sbjct: 66 RAETEIELSEAINVKGPQYLAEAAKSVGAAILHISTDYVFDGRRAGKYKETDATDPQSIY 125 Query: 122 GASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIVNDQF 181 G +K GE + K+ ++R A ++ + G NFV+ +++ A + L +V DQ Sbjct: 126 GKTKLAGEQAVVEANDKFIVLRTAWVFCE-----HGSNFVKTMLRLAKTRDTLGVVADQI 180 Query: 182 MSPTYTKDVARTLRELLR-----LRPSFGVYHMVNEGYCSWYEFTRAIFE------ILGW 230 PTY D+A L ++ +G+YH E Y SW +F RAIF+ +L Sbjct: 181 GGPTYAGDIAAALIQIAEKIIAGKSVEYGIYHFTGEPYVSWCDFARAIFDEAVSQNMLEK 240 Query: 231 DVRVKPINSSELKRLAKRPKFSALKNEKLEKI-GLKMKHWKEAL 273 V I +++ AKRP S L K++++ G++ W+ AL Sbjct: 241 VPLVNAITTADYPTPAKRPANSCLDLTKIQQVFGIQPSDWQRAL 284 >gb|AAF01815.1|AF187532_11 (AF187532) putative dTDP-4-dehydrorhamnose reductase [Streptomyces nogalater] Length = 291 Score = 145 bits (362), Expect = 6e-34 Identities = 92/263 (34%), Positives = 141/263 (52%), Gaps = 11/263 (4%) Query: 23 EAIPLTRKDLDVTDFESLKI-LKELKPEVIINTAAYVRVDDAELYPEEAFKVNAIGALNV 81 EA+ L R+ LD+TD ++ +P V++N AA+ VD AE EA +VN G + Sbjct: 21 EAVVLGRRALDITDGRAVDAAFAAHRPRVVVNCAAFTDVDGAESRWAEAMRVNGGGPRLL 80 Query: 82 ARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNPINVYGASKYIGEIFTRN-YSKKYY 140 AR G +++STDYVF G PY E D P P VYG SK GE + Sbjct: 81 ARRCARHGVRLIHVSTDYVFPGDTRSPYGESDAPGPRTVYGRSKLAGERAVLSLLPDTGT 140 Query: 141 IIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIVNDQFMSPTYTKDVARTLRELLRL 200 ++R A LYG G+G +FV ++++A + +VNDQ+ PT+ DVAR L L R Sbjct: 141 VVRTAWLYG-----GQGRSFVRTMLERAPDDGHVDVVNDQWGQPTWAGDVARLLVTLART 195 Query: 201 RP--SFGVYHMVNEGYCSWYEFTRAIFEILGWD-VRVKPINSSELKRLAKRPKFSALKNE 257 P + G++H N G +WYE R +F + G D RV+P+ +++ A RP + L ++ Sbjct: 196 PPDRARGIFHATNAGAATWYELAREVFRLAGADPERVRPVATADRPGPAPRPACTVLGHD 255 Query: 258 KLEKIGL-KMKHWKEALGEYLKE 279 + +G+ + W+ AL E +++ Sbjct: 256 RWRLVGVAPPRDWRAALREAMRQ 278 >pir||I69649 dTDP-6-deoxy-L-mannose-dehydrogenase - Escherichia coli Length = 299 Score = 143 bits (356), Expect = 3e-33 Identities = 93/298 (31%), Positives = 148/298 (49%), Gaps = 25/298 (8%) Query: 1 MRVAVIGANGQLGTDLVEVFGEEAIPLTRKDLDVTDFES--------LKILKELKPEVII 52 M + + G GQ+G +L L D+ TD+ + ++ ++P++I+ Sbjct: 1 MNILLFGKTGQVGWELQRALAPLG-NLIAFDVHSTDYCGDFSNPEGVAETVRSIRPDIIV 59 Query: 53 NTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEE 112 N AA+ VD AE PE A +NA +A+ ANE+GA ++ STDYVF G P+ E Sbjct: 60 NAAAHTAVDKAESEPEFAQLINATSVEAIAKAANEVGAWVIHYSTDYVFPGNGDMPWLET 119 Query: 113 DIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGE 172 D P+NVYG +K GE + Y K+ I R + +Y GKG NF + +++ A + E Sbjct: 120 DATAPLNVYGETKLAGEKALQEYCAKHLIFRTSWVYA-----GKGNNFAKTMLRLAKERE 174 Query: 173 ELRIVNDQFMSPT----YTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFE-- 226 EL ++NDQF +PT A +R L G+YH+V G +WY+++ +FE Sbjct: 175 ELAVINDQFGAPTGAELLADCTAHAIRVALNKPDVAGLYHLVASGTTTWYDYSALVFEEA 234 Query: 227 -ILGWDVRVKPIN---SSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEALGEYLKE 279 G + + +N ++ A+RP S L EK ++ L + W+ + L E Sbjct: 235 RKAGIPLALNKLNAVPTTAYPTPARRPHNSRLNTEKFQQNFALVLPDWQVGVKRMLNE 292 >gb|AAG09507.1|AF279617_2 (AF279617) dTDP-6-deoxy-L-mannose-dehydrogenase [Salmonella enterica] Length = 299 Score = 143 bits (356), Expect = 3e-33 Identities = 97/298 (32%), Positives = 156/298 (51%), Gaps = 25/298 (8%) Query: 1 MRVAVIGANGQLGTDL----VEVFGEEAIPLTRKDLDVTDFESLK----ILKELKPEVII 52 M + + G GQ+G +L V A+ + K+ DF + K +++L+P+VI+ Sbjct: 1 MNILLFGKTGQVGWELQRSLAPVGNLIALDVHSKEF-CGDFSNPKGVVETVRKLRPDVIV 59 Query: 53 NTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEE 112 N AA+ VD AE PE A +NA +A+ ANE GA V+ STDYVF G P+ E Sbjct: 60 NAAAHTAVDKAESEPELAQLLNATSVEAIAKAANETGAWVVHYSTDYVFPGTGDIPWQET 119 Query: 113 DIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGE 172 DI +P+NVYG +K GE ++ K+ I R + +Y GKG NF + +++ A + + Sbjct: 120 DITSPLNVYGKTKLTGEKALQDNCPKHLIFRTSWVYA-----GKGNNFAKTMLRLAKERQ 174 Query: 173 ELRIVNDQFMSPTYTKDVARTLRELLRL---RPSF-GVYHMVNEGYCSWYEFTRAIFE-- 226 L ++NDQ+ +PT + +A +R+ +P G+YH+V G +WY++ +F+ Sbjct: 175 TLSVINDQYGAPTGAELLADCTAHAIRMAFKKPEVAGLYHLVAGGTTTWYDYAALVFDEA 234 Query: 227 ----ILGWDVRVKPINSSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEALGEYLKE 279 I +K + +S + LA RP S L EK ++ GL + W+ + L E Sbjct: 235 RKAGITLALTELKAVPTSAYQTLASRPGNSRLNTEKFQRNFGLILPQWELGVKRMLTE 292 >sp|P37760|RBD1_ECOLI DTDP-4-DEHYDRORHAMNOSE REDUCTASE (DTDP-4-KETO-L-RHAMNOSE REDUCTASE) (DTDP-6-DEOXY-L-MANNOSE DEHYDROGENASE) (DTDP-L-RHAMNOSE SYNTHETASE) >gi|7436796|pir||G64969 dTDP-4-dehydrorhamnose reductase (EC 1.1.1.133) - Escherichia coli (strain K-12) >gi|1736730|dbj|BAA15882.1| (D90841) dTDP-4-dehydrorhamnose reductase (EC 1.1.1.133) (dTDP-4-keto-L- rhamnose reductase) (dTDP-6-deoxy-L-mannose dehydrogenase) (dTDP-L- rhamnose synthetase). [Escherichia coli] >gi|1736743|dbj|BAA15894.1| (D90842) dTDP-4-dehydrorhamnose reductase (EC 1.1.1.133) (dTDP-4-keto-L- rhamnose reductase) (dTDP-6-deoxy-L-mannose dehydrogenase) (dTDP-L- rhamnose synthetase). [Escherichia coli] >gi|1788352|gb|AAC75101.1| (AE000294) dTDP-6-deoxy-L-mannose-dehydrogenase [Escherichia coli K12] >gi|2665490|gb|AAB88399.1| (U09876) dTDP-6-deoxy-L-mannose-dehydrogenase [Escherichia coli] Length = 299 Score = 142 bits (355), Expect = 4e-33 Identities = 93/298 (31%), Positives = 147/298 (49%), Gaps = 25/298 (8%) Query: 1 MRVAVIGANGQLGTDLVEVFGEEAIPLTRKDLDVTDFES--------LKILKELKPEVII 52 M + + G GQ+G +L L D+ TD+ + ++ ++P++I+ Sbjct: 1 MNILLFGKTGQVGWELQRALAPLG-NLIAFDVHSTDYCGDFSNPEGVAETVRSIRPDIIV 59 Query: 53 NTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEE 112 N AA+ VD AE PE A +NA +A+ ANE+GA ++ STDYVF G P+ E Sbjct: 60 NAAAHTAVDKAESEPEFAQLINATSVEAIAKAANEVGAWVIHYSTDYVFPGNGDMPWLET 119 Query: 113 DIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGE 172 D P+NVYG +K GE + Y K+ I R + +Y GKG NF + +++ A + E Sbjct: 120 DATAPLNVYGETKLAGEKALQEYCAKHLIFRTSWVYA-----GKGNNFAKTMLRLAKERE 174 Query: 173 ELRIVNDQFMSPT----YTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFE-- 226 EL ++NDQF +PT A +R L G+YH+V G +WY++ +FE Sbjct: 175 ELAVINDQFGAPTGAELLADCTAHAIRVALNKPDVAGLYHLVASGTTTWYDYAALVFEEA 234 Query: 227 -ILGWDVRVKPIN---SSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEALGEYLKE 279 G + + +N ++ A+RP S L EK ++ L + W+ + L E Sbjct: 235 RKAGIPLALNKLNAVPTTAYPTPARRPHNSRLNTEKFQQNFALVLPDWQVGVKRMLNE 292 >pir||B36864 OAC2 protein - Azorhizobium caulinodans >gi|296708|emb|CAA80331.1| (Z22611) OAC2 [Azorhizobium caulinodans] Length = 296 Score = 141 bits (353), Expect = 7e-33 Identities = 96/274 (35%), Positives = 142/274 (51%), Gaps = 20/274 (7%) Query: 1 MRVAVIGANGQLGTDLVEVFGEEAIPLT---RKDLDVTDFESL-KILKELKPEVIINTAA 56 MRV ++GA+GQLG +L + E + L R D+TD ++ K L+ KP+V++N AA Sbjct: 1 MRVLLLGADGQLGRELTALAVERGLALAALNRAATDITDPVAVAKALEAHKPDVVVNAAA 60 Query: 57 YVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPN 116 Y VD AE P+ A KVNA+ +A G +++STDYVFDG K Y E D Sbjct: 61 YTAVDKAESEPDLAAKVNAVAPGLIAERCASAGVPLIHVSTDYVFDGTKTGAYVESDPLA 120 Query: 117 PINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRI 176 P+ VYG +K GE R +K+ I+R A +YG G NF++ +++ A + L I Sbjct: 121 PLGVYGRTKAAGEAAIRAAGEKHLILRTAWVYGI-----YGNNFLKTMLRLAKDRDRLTI 175 Query: 177 VNDQFMSPTYTKDVARTLRELLRLRPS------FGVYHMVNEGYCSWYEFTRAIFEILGW 230 V DQ PT T+D+A + L P+ +G YH+ G +W+ F +AI + Sbjct: 176 VADQRGCPTATRDIAEGI--LAAAAPAVAGSARWGTYHLGGTGVTTWHGFAQAIIDRAAT 233 Query: 231 DV---RVKPINSSELKRLAKRPKFSALKNEKLEK 261 V I ++E A+RP S L + E+ Sbjct: 234 YTGRSEVAAITTAEYPTPARRPANSELDSSLFER 267 >dbj|BAA19635.1| (AB002668) dTDP-4-rhamnose reductase [Actinobacillus actinomycetemcomitans] Length = 292 Score = 141 bits (353), Expect = 7e-33 Identities = 91/284 (32%), Positives = 147/284 (51%), Gaps = 20/284 (7%) Query: 5 VIGANGQLGTDLVEVFG--EEAIPLTRKDLDVTDFESLK-ILKELKPEVIINTAAYVRVD 61 + GANGQ+G L + E + + +LD+T+ ++K ++ +P+V+IN AA+ VD Sbjct: 6 ITGANGQVGYCLTQQLQGKHEILAVDHDELDITNQNAVKKTVENFRPDVVINAAAHTAVD 65 Query: 62 DAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNPINVY 121 AE E + +N G +A A +GA ++ISTDYVFDG + Y E D +P +Y Sbjct: 66 RAETEIELSEAINVKGPQYLAETAKSVGAAILHISTDYVFDGRRAGKYKETDAVDPQGIY 125 Query: 122 GASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIVNDQF 181 G +K GE + K+ ++R A ++ + G NFV+ +++ A + L +V DQ Sbjct: 126 GKTKLAGEQAVVEANDKFIVLRTAWVFCE-----HGSNFVKTMLRLAKTRDTLGVVADQI 180 Query: 182 MSPTYTKDVARTLRELLRL-----RPSFGVYHMVNEGYCSWYEFTRAIFE------ILGW 230 PTY D+A L ++ +G+YH E Y SW +F RAIF+ +L Sbjct: 181 GGPTYAGDIAAALIQIAEKIIAGESVEYGIYHFTGEPYVSWCDFARAIFDEAVSQNMLEK 240 Query: 231 DVRVKPINSSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEAL 273 V I +++ AKRP S L K+++ G++ W+ AL Sbjct: 241 APLVNAIITADYPTPAKRPANSCLDLTKIQQAFGIQPSDWQRAL 284 >dbj|BAA94404.1| (AB041266) dTDP-6-deoxy-L-lyxo-4-hexulose redactase [Actinobacillus actinomycetemcomitans] Length = 292 Score = 141 bits (352), Expect = 9e-33 Identities = 90/284 (31%), Positives = 145/284 (50%), Gaps = 20/284 (7%) Query: 5 VIGANGQLGTDLVEVFG--EEAIPLTRKDLDVTDFESLK-ILKELKPEVIINTAAYVRVD 61 + GANGQ+G L + E + + +LD+T+ ++K ++ +P+V+IN AA+ VD Sbjct: 6 ITGANGQVGYCLTQQLQGRHEILAVDHDELDITNQSAVKKTVENFRPDVVINAAAHTAVD 65 Query: 62 DAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNPINVY 121 AE E + +N G +A A + A ++ISTDYVFDG Y E D +P +Y Sbjct: 66 RAETEVERSEAINVKGPQYLAETAKSVDAAILHISTDYVFDGRSAGKYKETDAADPQGIY 125 Query: 122 GASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIVNDQF 181 G +K GE + K+ ++R A ++ + G NFV+ +++ A + L +V DQ Sbjct: 126 GKTKLAGEQAVVEANDKFIVLRTAWVFCE-----HGNNFVKTMLRLAKTRDTLGVVADQI 180 Query: 182 MSPTYTKDVARTLRELLRL-----RPSFGVYHMVNEGYCSWYEFTRAIFE------ILGW 230 PTY D+A L ++ +G+YH E Y SW +F RAIF+ +L Sbjct: 181 GGPTYAGDIAAALIQIAEKIIAGESVEYGIYHFTGEPYVSWCDFARAIFDEAVSQNMLEK 240 Query: 231 DVRVKPINSSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEAL 273 V I +++ AKRP S L K+++ G++ W+ AL Sbjct: 241 APLVNAITTADYPTPAKRPANSCLDLTKIQQAFGIQPSDWQRAL 284 >pir||C70978 probable rmlD protein - Mycobacterium tuberculosis (strain H37RV) >gi|1877321|emb|CAB07093.1| (Z92771) rmlD [Mycobacterium tuberculosis] Length = 304 Score = 139 bits (347), Expect = 3e-32 Identities = 101/286 (35%), Positives = 145/286 (50%), Gaps = 16/286 (5%) Query: 2 RVAVIGANGQLGTDLVEVF---GEEAIPLTRKDLDVTDFESL-KILKELKPEVIINTAAY 57 R+ + GA GQLG+ L G + + LT D+TD + +I++ +V+IN AAY Sbjct: 7 RLVITGAGGQLGSHLTAQAAREGRDMLALTSSQWDITDPAAAERIIRH--GDVVINCAAY 64 Query: 58 VRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFD----GAKGEPYTEED 113 VD AE A+ VNA G ++AR +GA +++STDYVFD GA+ PY D Sbjct: 65 TDVDGAESNEAVAYAVNATGPQHLARACARVGARLIHVSTDYVFDGDFGGAEPRPYEPTD 124 Query: 114 IPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEE 173 P VY SK GE + ++R A +Y G G +FV + + A Sbjct: 125 ETAPQGVYARSKLAGEQAVLAAFPEAAVVRTAWVY----TGGTGKDFVAVMRRLAAGHGR 180 Query: 174 LRIVNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFEILGWD-V 232 + +V+DQ SPTY D+A L L V H NEG S + RA+FE G D Sbjct: 181 VDVVDDQTGSPTYVADLAEALLALADAGVRGRVLHAANEGVVSRFGQARAVFEECGADPQ 240 Query: 233 RVKPINSSELKRLAKRPKFSALKNEKLEKIGL-KMKHWKEALGEYL 277 RV+P++S++ R A R +SAL + + GL ++HW+ AL L Sbjct: 241 RVRPVSSAQFPRPAPRSSYSALSSRQWALAGLTPLRHWRSALATAL 286 >gb|AAA53680.1| (L14842) dTDP-6-deoxy-D-glucose-3,5 epimerase [Shigella flexneri] Length = 299 Score = 137 bits (342), Expect = 1e-31 Identities = 91/298 (30%), Positives = 151/298 (50%), Gaps = 25/298 (8%) Query: 1 MRVAVIGANGQLGTDLVEVFGEEAIPLTRKDLDVTDFES--------LKILKELKPEVII 52 M + + G GQ+G +L L D+ TD+ + +K+++P+VI+ Sbjct: 1 MNILLFGKTGQVGWELQRALAPLG-NLIALDVHSTDYCGDFSNPEGVAETVKKIRPDVIV 59 Query: 53 NTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEE 112 N AA+ VD AE P A +NA +A+ ANE+GA ++ STDYVF G P+ E Sbjct: 60 NAAAHTAVDKAESEPNFAQLLNATCVEAIAKAANEVGAWVIHYSTDYVFPGNGDTPWLET 119 Query: 113 DIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGE 172 D P+NVYG +K GE + + K+ I R + +Y GKG NF + +++ A + E Sbjct: 120 DATAPLNVYGETKLAGEKALQEHCAKHLIFRTSWVYA-----GKGNNFAKTMLRLAKERE 174 Query: 173 ELRIVNDQFMSPTYTKDVARTLRELLRLRPS----FGVYHMVNEGYCSWYEFTRAIFE-- 226 EL ++NDQF +PT + +A +R+ + G+YH+V G +W+++ +FE Sbjct: 175 ELAVINDQFGAPTGAELLADCTAHAIRVAANKPEVAGLYHLVAGGTTTWHDYAALVFEEA 234 Query: 227 -ILGWDVRVKPIN---SSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEALGEYLKE 279 G ++ + +N ++ A+RP S L EK ++ L + W+ + L E Sbjct: 235 RRAGINLALNKLNAVPTTAYPTPARRPHNSRLNTEKFQQNFALVLPDWQVGVKRMLNE 292 >gb|AAF59936.1| (AF237895) 4-ketoreductase [Streptomyces antibioticus] Length = 294 Score = 137 bits (341), Expect = 2e-31 Identities = 94/281 (33%), Positives = 138/281 (48%), Gaps = 11/281 (3%) Query: 1 MRVAVIGANGQLGTDLVEVFGE---EAIPLTRKDLDVT-DFESLKILKELKPEVIINTAA 56 MR + GA G LG +LV E + L LDVT F L E +P +++N AA Sbjct: 1 MRWLITGAAGMLGRELVRRLAENEEDVAALGHDHLDVTRPFAVRAALAEHRPGIVVNCAA 60 Query: 57 YVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPN 116 Y VDDAE A +NA +A GA V++STDYVF G PY E+ Sbjct: 61 YTAVDDAETDEAAAALLNAEAPRLLAEACAPHGARLVHLSTDYVFPGDARTPYAEDHPTA 120 Query: 117 PINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRI 176 P + YG +K GE ++R A LYG+ G +FV +I++ +G + + Sbjct: 121 PRSAYGRTKRDGEQAVLTALPTATVLRTAWLYGRTGR-----SFVRTMIEREARGGAIDV 175 Query: 177 VNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFEILGWDV-RVK 235 V DQ PT+T D+A + + R G+ H N G +WY+ + +F +L D RV+ Sbjct: 176 VADQCGQPTWTGDLADRIIAVGRHPGVHGILHATNAGSATWYDLAQEVFRLLDADPGRVR 235 Query: 236 PINSSELKRLAKRPKFSALKNEKLEKIGL-KMKHWKEALGE 275 P + +R A RP +S L +++ GL ++ W+ AL E Sbjct: 236 PTTGAAFRRPAPRPAYSVLGHDRWRGTGLAPLRDWRSALRE 276 >gb|AAG09531.1|AF279623_2 (AF279623) dTDP-6-deoxy-L-mannose-dehydrogenase [Salmonella enterica] Length = 299 Score = 137 bits (341), Expect = 2e-31 Identities = 96/298 (32%), Positives = 152/298 (50%), Gaps = 25/298 (8%) Query: 1 MRVAVIGANGQLGTDL----VEVFGEEAIPLTRKDLDVTDFESLK----ILKELKPEVII 52 M + + G GQ+G +L V A+ + K+ DF + K +++L+P+VI+ Sbjct: 1 MNILLFGKTGQVGWELQRSLAPVGNLIALDVHSKEF-CGDFSNPKGVAETVRKLRPDVIV 59 Query: 53 NTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEE 112 N AA+ VD AE PE A +NA +A+ ANE GA V+ STDYVF G P+ E Sbjct: 60 NAAAHTAVDKAESEPELAQLLNATSVEAIAKAANETGAWVVHYSTDYVFPGTGDIPWQET 119 Query: 113 DIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGE 172 DI +P+NVYG +K GE ++ K+ I R + +Y GKG NF + +++ A + + Sbjct: 120 DITSPLNVYGKTKLAGEKALQDNGPKHLIFRTSWVYA-----GKGNNFAKTMLRLAKERQ 174 Query: 173 ELRIVNDQFMSPT----YTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFE-- 226 L ++NDQ+ +PT A +R L+ G+YH+V G +W+++ IF+ Sbjct: 175 TLSVINDQYGAPTGAELLADCTAHAIRVALKKPEVAGLYHLVAGGTTTWHDYAALIFDEA 234 Query: 227 -ILGWDVRVKPIN---SSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEALGEYLKE 279 G + + +N +S A RP S L EK ++ GL + W+ + L E Sbjct: 235 RKAGITLALTELNAVPTSAYPTPASRPGNSRLNTEKFQRNFGLILPQWELGVKRMLTE 292 >gb|AAG09514.1|AF279619_2 (AF279619) dTDP-6-deoxy-L-mannose-dehydrogenase [Salmonella enterica] Length = 299 Score = 136 bits (340), Expect = 2e-31 Identities = 92/297 (30%), Positives = 153/297 (50%), Gaps = 23/297 (7%) Query: 1 MRVAVIGANGQLGTDLVEVFGEE----AIPLTRKDL--DVTDFESL-KILKELKPEVIIN 53 M + + G NGQ+G +L A+ + KD D ++ E + + ++ ++P+VI+N Sbjct: 1 MNILLFGKNGQVGWELQRSLAPLGKIIALDVHSKDYCGDFSNPEGVAETIRRIRPDVIVN 60 Query: 54 TAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEED 113 AA+ VD AE E A +NA +A+ A+E GA V+ STDYVF G P+ E+D Sbjct: 61 AAAHTAVDKAESEVEFATLLNARSVEAIAKAASETGAWVVHYSTDYVFPGTGETPWCEDD 120 Query: 114 IPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEE 173 P+NVYG +K GE ++ ++ I R + +Y GKG NF + +++ A + EE Sbjct: 121 ATAPLNVYGETKLTGEKALQDNCARHLIFRTSWVYA-----GKGNNFAKTMLRFAKEREE 175 Query: 174 LRIVNDQFMSPT----YTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFE--- 226 + ++NDQ+ +PT A +R L+ G+YH+V G +WYE+ +F+ Sbjct: 176 MSVINDQYGAPTGAELLADCTAHAIRVALKQPEVAGLYHLVAGGTTTWYEYAALVFDEAR 235 Query: 227 ILGWDVRVKPIN---SSELKRLAKRPKFSALKNEKLE-KIGLKMKHWKEALGEYLKE 279 G ++ + +N +S A+RP S L +K + K L + W+ + L E Sbjct: 236 KAGIELAINKLNAVPTSAYPTPARRPNNSRLNTDKFQKKFDLVLPEWEIGVRRMLAE 292 >pir||C55213 rfbC protein - Shigella flexneri (strain 2a) Length = 299 Score = 136 bits (339), Expect = 3e-31 Identities = 91/298 (30%), Positives = 151/298 (50%), Gaps = 25/298 (8%) Query: 1 MRVAVIGANGQLGTDLVEVFGEEAIPLTRKDLDVTDFES--------LKILKELKPEVII 52 M + + G GQ+G +L L D+ TD+ + +K+++P+VI+ Sbjct: 1 MNILLFGKTGQVGWELQRALAPLG-NLIALDVHSTDYCGDFSNPEGVAETVKKIRPDVIV 59 Query: 53 NTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEE 112 N AA+ VD AE P A +NA +A+ ANE+GA ++ STDYVF G P+ E Sbjct: 60 NAAAHTAVDKAESEPNFAQLLNATCVEAIAKAANEVGAWVIHYSTDYVFPGNGDTPWLET 119 Query: 113 DIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGE 172 D P+NVYG +K GE + + K+ I R + +Y GKG NF + +++ A + E Sbjct: 120 DATAPLNVYGETKLAGEKALQEHCAKHLIFRTSWVYA-----GKGNNFAKTMLRLAKERE 174 Query: 173 ELRIVNDQFMSPTYTKDVARTLRELLRLRPS----FGVYHMVNEGYCSWYEFTRAIFE-- 226 EL ++NDQF +PT + +A +R+ + G+YH+V G +W+++ +FE Sbjct: 175 ELAVINDQFGAPTGAELLADCTAAHIRVAANKPEVAGLYHLVAGGTTTWHDYAALVFEEA 234 Query: 227 -ILGWDVRVKPIN---SSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEALGEYLKE 279 G ++ + +N ++ A+RP S L EK ++ L + W+ + L E Sbjct: 235 RRAGINLALNKLNAVPTTAYPTPARRPHNSRLNTEKFQQNFALVLPDWQVGVKRMLNE 292 >gb|AAG09527.1|AF279622_2 (AF279622) dTDP-6-deoxy-L-mannose-dehydrogenase [Salmonella enterica] Length = 299 Score = 136 bits (339), Expect = 3e-31 Identities = 95/298 (31%), Positives = 152/298 (50%), Gaps = 25/298 (8%) Query: 1 MRVAVIGANGQLGTDL----VEVFGEEAIPLTRKDLDVTDFESLK----ILKELKPEVII 52 M + + G GQ+G +L V A+ + K+ DF + K +++L+P+VI+ Sbjct: 1 MNILLFGKTGQVGWELQRSLAPVGNLIALDVHSKEF-CGDFSNPKGVAETVRKLRPDVIV 59 Query: 53 NTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEE 112 N AA+ VD AE PE A +NA +A+ ANE GA V+ STDYVF G P+ E Sbjct: 60 NAAAHTAVDKAESEPELAQLLNATSVEAIAKAANETGAWVVHYSTDYVFPGTGDIPWQET 119 Query: 113 DIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGE 172 DI +P+NVYG +K GE ++ K+ I R + +Y GKG NF + +++ A + + Sbjct: 120 DITSPLNVYGKTKLAGEKALQDSCPKHLIFRTSWVYA-----GKGNNFAKTMLRLAKERQ 174 Query: 173 ELRIVNDQFMSPT----YTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFE-- 226 L ++NDQ+ +PT A +R L+ G+YH+V G +W+++ +F+ Sbjct: 175 TLSVINDQYGAPTGAELLADCTAHAIRVALKKPEVAGLYHLVAGGTTTWHDYAALVFDEA 234 Query: 227 -ILGWDVRVKPIN---SSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEALGEYLKE 279 G + + +N +S A RP S L EK ++ GL + W+ + L E Sbjct: 235 RKAGITLALTELNAVPTSAYPTPASRPGNSRLNTEKFQRNFGLILPQWELGVKRMLTE 292 >gb|AAG09510.1|AF279618_2 (AF279618) dTDP-6-deoxy-L-mannose-dehydrogenase [Salmonella enterica] Length = 299 Score = 136 bits (338), Expect = 4e-31 Identities = 95/298 (31%), Positives = 151/298 (49%), Gaps = 25/298 (8%) Query: 1 MRVAVIGANGQLGTDL----VEVFGEEAIPLTRKDLDVTDFESLK----ILKELKPEVII 52 M + + G GQ+G +L V A+ + K+ DF + K +++L+P+VI+ Sbjct: 1 MNILLFGKTGQVGWELQRSLAPVGNLIALDVHSKEF-CGDFSNPKGVAETVRKLRPDVIV 59 Query: 53 NTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEE 112 N AA+ VD AE PE A +NA +A+ ANEIGA V+ STDYVF G P+ E Sbjct: 60 NAAAHTAVDKAESEPELAQLLNATSVEAIAKAANEIGAWVVHYSTDYVFPGTGDIPWQET 119 Query: 113 DIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGE 172 D +P+NVYG +K GE ++ K+ I R + +Y GKG NF + +++ A + + Sbjct: 120 DATSPLNVYGKTKLAGEKALQDNCPKHLIFRTSWVYA-----GKGNNFAKTMLRLAKERQ 174 Query: 173 ELRIVNDQFMSPT----YTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFE-- 226 L ++NDQ+ +PT A +R L+ G+YH+V G +W+++ +F+ Sbjct: 175 TLSVINDQYGAPTGAELLADCTAHAIRVALKKPEVAGLYHLVAGGTTTWHDYAALVFDEA 234 Query: 227 -ILGWDVRVKPIN---SSELKRLAKRPKFSALKNEKLE-KIGLKMKHWKEALGEYLKE 279 G + + +N +S A RP S L EK + GL + W+ + L E Sbjct: 235 RKAGLTLALTELNAVPTSAYPTPASRPGNSRLNTEKFQSNFGLILPQWELGVKRMLTE 292 >gb|AAG09523.1|AF279621_2 (AF279621) dTDP-6-deoxy-L-mannose-dehydrogenase [Salmonella enterica] Length = 299 Score = 136 bits (338), Expect = 4e-31 Identities = 95/298 (31%), Positives = 151/298 (49%), Gaps = 25/298 (8%) Query: 1 MRVAVIGANGQLGTDL----VEVFGEEAIPLTRKDLDVTDFESLK----ILKELKPEVII 52 M + + G GQ+G +L V A+ + K+ DF + K +++L+P+VI+ Sbjct: 1 MNILLFGKTGQVGWELQRSLAPVGNLIALDVHSKEF-CGDFSNPKGVAETVRKLRPDVIV 59 Query: 53 NTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEE 112 N AA+ VD AE PE A +NA +A+ ANE GA V+ STDYVF G P+ E Sbjct: 60 NAAAHTAVDKAESEPELAQLLNATSVEAIAKAANETGAWVVHYSTDYVFPGTGDIPWQET 119 Query: 113 DIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGE 172 DI +P+NVYG +K GE ++ K+ I R + +Y GKG NF + +++ A + + Sbjct: 120 DITSPLNVYGKTKLAGEKALQDNCPKHLIFRTSWVYA-----GKGNNFAKTMLRLAKERQ 174 Query: 173 ELRIVNDQFMSPT----YTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFE-- 226 L ++NDQ+ +PT A +R L G+YH+V G +W+++ +F+ Sbjct: 175 TLSVINDQYGAPTGAELLADCTAHAIRVALNKPEVAGLYHLVAGGTTTWHDYAALVFDEA 234 Query: 227 -ILGWDVRVKPIN---SSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEALGEYLKE 279 G + + +N +S A RP S L EK ++ GL + W+ + L E Sbjct: 235 RKAGLTLALTELNAVPTSAYPTPASRPGNSRLNTEKFQRNFGLILPQWELGVKRMLTE 292 >gb|AAG09503.1|AF279616_2 (AF279616) dTDP-6-deoxy-L-mannose-dehydrogenase [Salmonella enterica] Length = 299 Score = 135 bits (336), Expect = 7e-31 Identities = 94/298 (31%), Positives = 151/298 (50%), Gaps = 25/298 (8%) Query: 1 MRVAVIGANGQLGTDL----VEVFGEEAIPLTRKDLDVTDFESLK----ILKELKPEVII 52 M + + G GQ+G +L V A+ + K+ DF + K +++L+P+VI+ Sbjct: 1 MNILLFGKTGQVGWELQRSLAPVGNLTALDVHSKEF-CGDFSNPKGVAETVRKLRPDVIV 59 Query: 53 NTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEE 112 N AA+ VD AE PE A +NA +A+ ANE GA V+ STDYVF G P+ E Sbjct: 60 NAAAHTAVDKAESEPELAQLLNATSVEAIAKAANETGAWVVHYSTDYVFPGTGDIPWQET 119 Query: 113 DIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGE 172 D +P+NVYG +K GE ++ K+ I R + +Y GKG NF + +++ A + + Sbjct: 120 DATSPLNVYGKTKLAGEKALQDNCPKHLIFRTSWVYA-----GKGNNFAKTMLRLAKERQ 174 Query: 173 ELRIVNDQFMSPT----YTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFE-- 226 L ++NDQ+ +PT A +R L+ G+YH+V G +W+++ +F+ Sbjct: 175 TLSVINDQYGAPTGAELLADCTAHAIRVALKKPEVAGLYHLVAGGTTTWHDYAALVFDEA 234 Query: 227 -ILGWDVRVKPIN---SSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEALGEYLKE 279 G + + +N +S A RP S L EK ++ GL + W+ + L E Sbjct: 235 RKAGITLALTELNAVPTSAYPTPASRPGNSRLNTEKFQRNFGLILPQWELGVKRMLTE 292 >gb|AAC44075.1| (U51197) dTDP-6-deoxy-L-mannose-dehydrogenase [Sphingomonas sp. S88] Length = 288 Score = 134 bits (335), Expect = 9e-31 Identities = 92/286 (32%), Positives = 150/286 (52%), Gaps = 16/286 (5%) Query: 1 MRVAVIGANGQLGTDLVE-VFGEEAIPLTRKDLDVTDFESLKI-LKELKPEVIINTAAYV 58 MR+ V G +GQ+ L E G E I + + D++ E+++ + +++PE+I++ AAY Sbjct: 1 MRILVTGHDGQVAQALGEQAEGHELIFTSYPEFDLSKPETIEAAVAKIQPELIVSAAAYT 60 Query: 59 RVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNPI 118 VD +E PE A +N G +AR +IGA +++STDYVFDG+ P+ E+D P+ Sbjct: 61 AVDKSESEPELAMAINGDGPGVLARAGAKIGAPIIHLSTDYVFDGSLDRPWREDDPTGPL 120 Query: 119 NVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIVN 178 VYGA+K GE + +IR+A +Y G NFV+ +++ A + L +V Sbjct: 121 GVYGATKLAGEQAVQASGATNAVIRLAWVYSPF-----GNNFVKTMLRLAETRDTLNVVE 175 Query: 179 DQFMSPTYTKDVARTLRELL----RLRPSFGVYHMVNEGYCSWYEFTRAIF----EILGW 230 DQ P+ D+A + +++ + + G+YH G +W +F RAIF + G Sbjct: 176 DQQGCPSSALDIATAILKVVGHWQQNGATSGLYHFTGSGETNWADFARAIFAESAKHGGP 235 Query: 231 DVRVKPINSSELKRLAKRPKFSALKNEKL-EKIGLKMKHWKEALGE 275 V I +S AKRP S L +K E G + W++++ E Sbjct: 236 TAEVTGIPTSGYPTPAKRPANSRLNCDKFAETFGYRAPAWQDSVAE 281 >gb|AAG09535.1|AF279624_2 (AF279624) dTDP-6-deoxy-L-mannose-dehydrogenase [Salmonella enterica] Length = 299 Score = 134 bits (335), Expect = 9e-31 Identities = 95/298 (31%), Positives = 151/298 (49%), Gaps = 25/298 (8%) Query: 1 MRVAVIGANGQLGTDL----VEVFGEEAIPLTRKDLDVTDFESLK----ILKELKPEVII 52 M + + G GQ+G +L V A+ + K+ DF + K +++L+P+VI+ Sbjct: 1 MNILLFGKTGQVGWELQRSLAPVGNLIALDVHSKEF-CGDFSNPKGVAETVRKLRPDVIV 59 Query: 53 NTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEE 112 N AA+ VD AE PE A +NA +A+ ANE GA V+ STDYVF G P+ E Sbjct: 60 NAAAHTAVDKAESEPELAQLLNATSVEAIAKAANETGAWVVHYSTDYVFPGTGDIPWQET 119 Query: 113 DIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGE 172 DI +P+NVYG +K GE + K+ I R + +Y GKG NF + +++ A + + Sbjct: 120 DITSPLNVYGKTKLAGEKALQCNCPKHLIFRTSWVYA-----GKGNNFAKTMLRLAKERQ 174 Query: 173 ELRIVNDQFMSPT----YTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFE-- 226 L ++NDQ+ +PT A +R L+ G+YH+V G +W+++ +F+ Sbjct: 175 TLSVINDQYGAPTGAELLADCTAHAIRVALKKPEVAGLYHLVAGGTTTWHDYAALVFDEA 234 Query: 227 -ILGWDVRVKPIN---SSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEALGEYLKE 279 G + + +N +S A RP S L EK ++ GL + W+ + L E Sbjct: 235 RKAGITLALTELNAVPTSAYPTPASRPGNSRLNTEKFQRNFGLILPQWELGVKRMLTE 292 >gb|AAG09499.1|AF279615_2 (AF279615) dTDP-6-deoxy-L-mannose-dehydrogenase [Salmonella enterica] Length = 299 Score = 134 bits (334), Expect = 1e-30 Identities = 94/298 (31%), Positives = 151/298 (50%), Gaps = 25/298 (8%) Query: 1 MRVAVIGANGQLGTDL----VEVFGEEAIPLTRKDLDVTDFESLK----ILKELKPEVII 52 M + + G GQ+G +L V A+ + K+ DF + K +++L+P+VI+ Sbjct: 1 MNILLFGKTGQVGWELQRSLAPVGNLIALDVHSKEF-CGDFSNPKGVAETVRKLRPDVIV 59 Query: 53 NTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEE 112 N AA+ VD AE PE A +NA +A+ ANE GA V+ STDYVF G P+ E Sbjct: 60 NAAAHTAVDKAESEPELAQLLNATSVEAIAKAANETGAWVVHYSTDYVFPGTGDIPWQET 119 Query: 113 DIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGE 172 D +P+NVYG +K GE ++ K+ I R + +Y GKG NF + +++ A + + Sbjct: 120 DATSPLNVYGKTKLAGEKALQDNCPKHLIFRTSWVYA-----GKGNNFAKTMLRLAKERQ 174 Query: 173 ELRIVNDQFMSPT----YTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFE-- 226 L ++NDQ+ +PT A +R +L G+YH+V G +W+++ +F+ Sbjct: 175 TLSVINDQYGAPTGAELLADCTAHAIRVVLNKPEVAGLYHLVAGGTTTWHDYAALVFDEA 234 Query: 227 -ILGWDVRVKPIN---SSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEALGEYLKE 279 G + + +N +S A RP S L EK ++ GL + W+ + L E Sbjct: 235 RKAGITLALTELNAVPTSAYPTPASRPGNSRLNTEKFQRNFGLILPQWELGVKRMLTE 292 >gb|AAG09518.1|AF279620_2 (AF279620) dTDP-6-deoxy-L-mannose-dehydrogenase [Salmonella enterica] Length = 299 Score = 134 bits (333), Expect = 2e-30 Identities = 94/298 (31%), Positives = 151/298 (50%), Gaps = 25/298 (8%) Query: 1 MRVAVIGANGQLGTDL----VEVFGEEAIPLTRKDLDVTDFESLK----ILKELKPEVII 52 M + + G GQ+G +L V A+ + K+ DF + K +++L+P+VI+ Sbjct: 1 MNILLFGKTGQVGWELQRSLAPVGNLIALDVHSKEF-CGDFSNPKGVAETVRKLRPDVIV 59 Query: 53 NTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEE 112 N AA+ VD AE PE A +NA +A+ ANE GA V+ STDYVF G P+ E Sbjct: 60 NAAAHTAVDKAESEPELAQLLNATSVEAIAKAANETGAWVVHYSTDYVFPGTGDIPWQET 119 Query: 113 DIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGE 172 DI +P+NVYG +K GE ++ K+ I R + +Y GKG NF + +++ A + + Sbjct: 120 DITSPLNVYGKTKLAGEKALQDNCPKHLIFRTSWVYA-----GKGNNFAKTMLRLAKERQ 174 Query: 173 ELRIVNDQFMSPT----YTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFE-- 226 L ++NDQ+ +PT A +R L+ G+YH+V G +W+++ +F+ Sbjct: 175 TLSVINDQYGAPTGAELLADCTAHAIRVALKKPEVAGLYHLVAGGTTTWHDYAALVFDEA 234 Query: 227 -ILGWDVRVKPIN---SSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEALGEYLKE 279 G + + +N +S A RP S L EK ++ L + W+ + L E Sbjct: 235 RKAGITLALTELNAVPTSAYPTSANRPGNSRLNTEKFQRNFDLILPQWELGVKRMLTE 292 >pir||T00085 dTDP-4-dehydrorhamnose reductase (EC 1.1.1.133) - Streptococcus mutans (fragment) >gi|3399703|dbj|BAA32088.1| (AB010970) dTDP-4-keto-L-rhamonose reductase [Streptococcus mutans] Length = 219 Score = 131 bits (326), Expect = 1e-29 Identities = 77/213 (36%), Positives = 113/213 (52%), Gaps = 11/213 (5%) Query: 71 FKVNAIGALNVARIANEIGAINVYISTDYVFDGAK--GEPYTEEDIPNPINVYGASKYIG 128 + +N G N+A+ + A VYISTDYVFDG K G+ + +D P+P YG +K +G Sbjct: 10 YAINVTGTENIAKACEKYNATLVYISTDYVFDGEKPVGQEWEVDDKPDPKTEYGRTKRLG 69 Query: 129 EIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIVNDQFMSPTYTK 188 E Y K +YIIR A ++G G NFV + A L +VNDQ PT+T+ Sbjct: 70 EEAVEKYVKNFYIIRTAWVFGNYGK-----NFVFTMQHLAKSHNSLTVVNDQHGRPTWTR 124 Query: 189 DVARTLRELLRLRPSFGVYHMVNEGY--CSWYEFTRAIFEILGWDVRVKPINSSELKRLA 246 +A + L + +G YH+ N+ +WY+F I + DV VKP++SS+ A Sbjct: 125 TLAEFMTYLAENQKEYGYYHLSNDATEDTTWYDFALEILK--DTDVVVKPVDSSQFPAKA 182 Query: 247 KRPKFSALKNEKLEKIGLKMKHWKEALGEYLKE 279 KRP S + K + G + W+EAL E+ K+ Sbjct: 183 KRPLNSTMSLTKAKATGFVIPTWQEALQEFYKQ 215 >sp|P26392|RFBD_SALTY DTDP-4-DEHYDRORHAMNOSE REDUCTASE (DTDP-4-KETO-L-RHAMNOSE REDUCTASE) (DTDP-6-DEOXY-L-MANNOSE DEHYDROGENASE) (DTDP-L-RHAMNOSE SYNTHETASE) >gi|96839|pir||S15300 rfbA protein - Salmonella typhimurium >gi|47890|emb|CAA40116.1| (X56793) dTDP-6-deoxy-L-mannose dehydrogenase [Salmonella enterica] Length = 299 Score = 131 bits (325), Expect = 1e-29 Identities = 93/298 (31%), Positives = 149/298 (49%), Gaps = 25/298 (8%) Query: 1 MRVAVIGANGQLGTDL----VEVFGEEAIPLTRKDLDVTDFESLK----ILKELKPEVII 52 M + + G GQ+G +L V A+ + K+ DF + K +++L+P+VI+ Sbjct: 1 MNILLFGKTGQVGWELQRSLAPVGNLIALDVHSKEF-CGDFSNPKGVAETVRKLRPDVIV 59 Query: 53 NTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEE 112 N AA+ VD AE PE A +NA +A+ ANE GA V+ STDYVF G P+ E Sbjct: 60 NAAAHTAVDKAESEPELAQLLNATSVEAIAKAANETGAWVVHYSTDYVFPGTGDIPWQET 119 Query: 113 DIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGE 172 D +P+NVYG +K GE ++ K+ I R + +Y GKG NF + +++ A + + Sbjct: 120 DATSPLNVYGKTKLAGEKALQDNCPKHLIFRTSWVYA-----GKGNNFAKTMLRLAKERQ 174 Query: 173 ELRIVNDQFMSPT----YTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFE-- 226 L ++NDQ+ +PT A +R L G+YH+V G +W+++ +F+ Sbjct: 175 TLSVINDQYGAPTGAELLADCTAHAIRVALNKPEVAGLYHLVAGGTTTWHDYAALVFDEA 234 Query: 227 -ILGWDVRVKPIN---SSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEALGEYLKE 279 G + + +N +S A RP S L EK ++ L + W+ + L E Sbjct: 235 RKAGITLALTELNAVPTSAYPTPASRPGNSRLNTEKFQRNFDLILPQWELGVKRMLTE 292 >gb|AAG09538.1|AF279625_2 (AF279625) dTDP-6-deoxy-L-mannose-dehydrogenase [Salmonella enterica] Length = 299 Score = 129 bits (320), Expect = 5e-29 Identities = 90/297 (30%), Positives = 146/297 (48%), Gaps = 23/297 (7%) Query: 1 MRVAVIGANGQLGTDL---VEVFGEEAIPLTRKDLDVTDFESLK----ILKELKPEVIIN 53 M + + G GQ+G +L + G + DF + K +++L+P+VI+N Sbjct: 1 MNILLFGKTGQVGWELQRSLAPVGNLIVLDVHSKEFCGDFSNPKGVAETVRKLRPDVIVN 60 Query: 54 TAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEED 113 AA+ VD AE PE A +NA +A+ ANE G+ V+ STDYVF G P+ E D Sbjct: 61 AAAHTAVDKAESEPELAQLLNATSVEAIAKAANETGSWVVHYSTDYVFPGTGDIPWQETD 120 Query: 114 IPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEE 173 +P+NVYG +K GE ++ K+ I R + +Y GKG NF + +++ A + + Sbjct: 121 ATSPLNVYGKTKLAGEKALQDNCPKHLIFRTSWVYA-----GKGNNFAKTMLRLAKERQT 175 Query: 174 LRIVNDQFMSPT----YTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFE--- 226 L ++NDQ+ +PT A +R L G+YH+V G +W+++ +F+ Sbjct: 176 LSVINDQYGAPTGAELLADCTAHAIRVALNKPEVAGLYHLVAGGTTTWHDYAALVFDEAR 235 Query: 227 ILGWDVRVKPIN---SSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEALGEYLKE 279 G + + +N +S A RP S L EK ++ L + W+ + L E Sbjct: 236 KAGITLALTELNAVPTSAYPTSASRPGNSRLNTEKFQRNFDLILPQWELGVKRMLTE 292 >emb|CAB01952.1| (Z79692) ExpA10 [Sinorhizobium meliloti] Length = 275 Score = 128 bits (319), Expect = 7e-29 Identities = 88/261 (33%), Positives = 134/261 (50%), Gaps = 19/261 (7%) Query: 23 EAIPLTRKDLDVTDFES-LKILKELKPEVIINTAAYVRVDDAELYPEEAFKVNAIGALNV 81 E + + R LD+T+ + L ++ +P+++++ AAY VD AE PE AF VNA GA V Sbjct: 2 EVVTIGRPHLDLTEPATILPAIERCRPDLVVSAAAYTAVDQAESEPEAAFAVNAFGAGAV 61 Query: 82 ARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNPINVYGASKYIGEIFTRNYSKKYYI 141 A A + V+ISTDYVFDG+K Y E D P P++VYGASK GE + ++ I Sbjct: 62 AEAAACLEVPIVHISTDYVFDGSKPRSYAEGDTPAPLSVYGASKLAGESAVAEATPRHLI 121 Query: 142 IRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIVNDQFMSPTYTKDVARTLREL---- 197 +R +Y G NFV+ +++ A + E++ +V DQ +P+ D+A + ++ Sbjct: 122 LRTGWVYSPFGK-----NFVKTILRLAEEREDIAVVADQRGNPSSAIDLADAILDISARL 176 Query: 198 --LRLRPSFGVYHMVNEGYCSWYEFTR---AIFEILG--WDVRVKPINSSELKRLAKRPK 250 R +FG+YH+ G S +F R A G W V+ I + A RP Sbjct: 177 TKSRQDAAFGLYHLAGSGVVSRADFARHALAASRAAGGPW-AHVRDIATGGFPTPASRPA 235 Query: 251 FSALKNEKLE-KIGLKMKHWK 270 S+L + K G M W+ Sbjct: 236 NSSLSSAKFNATFGQAMPAWQ 256 >pir||G70346 spore coat polysaccharide biosynthesis protein SpsK - Aquifex aeolicus >gi|2983168|gb|AAC06769.1| (AE000694) spore coat polysaccharide biosynthesis protein SpsK [Aquifex aeolicus] Length = 137 Score = 128 bits (319), Expect = 7e-29 Identities = 59/129 (45%), Positives = 86/129 (65%), Gaps = 4/129 (3%) Query: 149 GKAGARGKGGNFVEWVIKKANKGEELRIVNDQFMSPTYTKDVARTLRELLRLRPSFGVYH 208 GKAGA KGGNFV +I+KA GE LR+V+D +MSPTYT D A+ + ++L +G+YH Sbjct: 3 GKAGASSKGGNFVYTIIRKAKAGEPLRVVDDIYMSPTYTLDAAKEIWKILLENKPYGIYH 62 Query: 209 MVNEGYCSWYEFTRAIFEILGWDVRVKPINSSELKRLAKRPKFSALKNEKLEKIGLKMKH 268 + N GYCSWYEF I E G +KP+ +E K A RP +S L +++ G+K+++ Sbjct: 63 VTNSGYCSWYEFAVKILEYSGLKTDIKPVRHTEFKTKANRPLWSPLASKR----GIKLRN 118 Query: 269 WKEALGEYL 277 W+EAL +++ Sbjct: 119 WEEALKDFI 127 >pir||T51107 4-ketoreductase [validated] - Streptomyces antibioticus (ATCC 11891) >gi|5902171|gb|AAD55455.1| (AF055579) 4-ketoreductase [Streptomyces antibioticus] Length = 295 Score = 127 bits (317), Expect = 1e-28 Identities = 93/284 (32%), Positives = 140/284 (48%), Gaps = 16/284 (5%) Query: 1 MRVAVIGANGQLGTDLVEVFGE---EAIPLTRKDLDVTDFESLKI-LKELKPEVIINTAA 56 MR + GA G LG +LV E + L LDVT +++ L E +P +++N AA Sbjct: 1 MRWLITGAAGMLGRELVRRLAENEEDVAALGHDHLDVTRPSAVRAALAEHRPGIVVNCAA 60 Query: 57 YVRVDDAELYPEEAFKVNAIGALNVA---RIANEIGAINVYISTDYVFDGAKGEPYTEED 113 Y VDDAE A +NA +A R G V++STDYVF G PY E+ Sbjct: 61 YTAVDDAETDEAAAALLNAEAPRLLAEGLRPHRRHGL--VHLSTDYVFPGDARTPYAEDH 118 Query: 114 IPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEE 173 P + YG +K GE ++R A LYG+ G +FV +I++ +G Sbjct: 119 PTAPRSAYGRTKRDGEQAVLTALPTATVLRTAWLYGRTGR-----SFVRTMIEREARGGA 173 Query: 174 LRIVNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFEILGWDV- 232 + +V DQ PT+T D+A + + R G+ H N G +WY+ + +F +L D Sbjct: 174 IDVVADQRGQPTWTGDLADRIIAVGRHPGVHGILHATNAGSATWYDLAQEVFRLLDADPG 233 Query: 233 RVKPINSSELKRLAKRPKFSALKNEKLEKIGL-KMKHWKEALGE 275 RV+P + +R A RP +S L +++ GL ++ W+ AL E Sbjct: 234 RVRPTTGAAFRRPAPRPAYSVLGHDRWRGTGLAPLRDWRSALRE 277 >pir||S23348 hypothetical protein 5.2 - Salmonella choleraesuis >gi|431939|emb|CAA43073.1| (X60665) dTDP-6-deoxy-L-mannose dehydrogenase [Salmonella enterica] Length = 248 Score = 126 bits (314), Expect = 3e-28 Identities = 81/246 (32%), Positives = 127/246 (50%), Gaps = 16/246 (6%) Query: 45 ELKPEVIINTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGA 104 +L+P+VI+N AA+ VD AE PE A +NA +A+ ANE GA V+ STDYVF G Sbjct: 1 KLRPDVIVNAAAHTAVDKAESEPELAQLLNATSVEAIAKAANETGAWVVHYSTDYVFPGT 60 Query: 105 KGEPYTEEDIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWV 164 P+ E D +P+NVYG +K GE ++ K+ I R + +Y GKG NF + + Sbjct: 61 GDIPWQETDATSPLNVYGKTKLAGEKALQDNCPKHLIFRTSWVYA-----GKGNNFAKTM 115 Query: 165 IKKANKGEELRIVNDQFMSPT----YTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEF 220 ++ A + + L ++NDQ+ +PT A +R L G+YH+V G +W+++ Sbjct: 116 LRLAKERQTLSVINDQYGAPTGAELLADCTAHAIRVALNKPEVAGLYHLVAGGTTTWHDY 175 Query: 221 TRAIFE---ILGWDVRVKPIN---SSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEAL 273 +F+ G + + +N +S A RP S L EK ++ L + W+ + Sbjct: 176 AALVFDEARKAGITLALTELNAVPTSAYPTPASRPGNSRLNTEKFQRNFDLILPQWELGV 235 Query: 274 GEYLKE 279 L E Sbjct: 236 KRMLTE 241 >sp|Q46769|RBD2_ECOLI DTDP-4-DEHYDRORHAMNOSE REDUCTASE (DTDP-4-KETO-L-RHAMNOSE REDUCTASE) (DTDP-6-DEOXY-L-MANNOSE DEHYDROGENASE) (DTDP-L-RHAMNOSE SYNTHETASE) >gi|7436795|pir||S78543 dTDP-4-dehydrorhamnose reductase (EC 1.1.1.133) - Escherichia coli (strain VW187) >gi|799233|gb|AAC63613.1| (AF125322) RmlD [Escherichia coli] Length = 301 Score = 123 bits (307), Expect = 2e-27 Identities = 91/300 (30%), Positives = 150/300 (49%), Gaps = 27/300 (9%) Query: 1 MRVAVIGANGQLGTDLVEVFGEEAIPLTRKDLDVTDFES--------LKILKELKPEVII 52 M + + G GQ+G +L L D+ TD+ + +K+++P+VI+ Sbjct: 1 MNILLFGKTGQVGWELQRALAPLG-NLIALDVHSTDYCGDFSNPEGVAETVKKIRPDVIV 59 Query: 53 NTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYT-E 111 N AA+ VD AE PE A +NA +A+ ANE+GA ++ STDYVF G P+ Sbjct: 60 NAAAHTDVDKAESEPEFAQLLNATSVEAIAKAANEVGAWVIHYSTDYVFPGTGEIPWQGG 119 Query: 112 EDIPNPINVYGASKYIGE-IFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANK 170 D P+NVYG +K E + + K+ I R + +Y GKG NF + +++ A + Sbjct: 120 TDATAPLNVYGETKLSSEKKALQKHCGKHIIFRTSWVYA-----GKGNNFAKTMLRLAKE 174 Query: 171 GEELRIVNDQFMSPTYTKDVARTLRELLRL---RPSF-GVYHMVNEGYCSWYEFTRAIFE 226 EEL ++NDQF PT + +A +R+ +P G+YH+V G +W+++ +FE Sbjct: 175 REELAVINDQFGRPTGAELLADCTAHAIRVAVDKPEVAGLYHLVAGGTTTWHDYAALVFE 234 Query: 227 ---ILGWDVRVKPIN---SSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEALGEYLKE 279 G ++ + +N ++ A+RP S L EK ++ L + W+ + L E Sbjct: 235 EARKAGINLALNKLNAVPTTAYPTPARRPHNSRLNTEKFQQNFALVLPDWQVGVKRMLNE 294 >pir||C49906 rfbC homolog - Xanthomonas campestris pv. campestris >gi|398117|gb|AAA16189.1| (L23941) putative [Xanthomonas campestris] Length = 302 Score = 119 bits (295), Expect = 4e-26 Identities = 92/301 (30%), Positives = 140/301 (45%), Gaps = 27/301 (8%) Query: 1 MRVAVIGANGQLGTDLVEVFGEE-AIPLTRKD--------LDVTDFESLK----ILKELK 47 M V GANGQ+G +L+ + A+ T + + DF++ + +L + Sbjct: 1 MTTLVFGANGQVGAELLRALAADGAVQATTRSGRLPDGSACETADFDAPETLPALLDRIG 60 Query: 48 PEVIINTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGE 107 P +++N AAY VD AE A + NA L +A V+ STDYVFDG Sbjct: 61 PSLVVNAAAYTAVDCAEQDRVSAMRANAQAPLTIAAWCAARDVPLVHYSTDYVFDGQDTA 120 Query: 108 PYTEEDIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKK 167 PY E+ +P+ VYG +K GE R ++ + YG G R F + Sbjct: 121 PYLEDAQTSPLGVYGETKLAGENAIRASGAQH----LDPAYG-MGVRIARREFPAHHVAC 175 Query: 168 ANKGEELRIVNDQFMSPTYTKDVARTLRELLRLR--PSFGVYHMVNEGYCSWYEFTRAIF 225 + +ELR+V DQ +P+ +A +LLR R + G +H+ G SW+ F AIF Sbjct: 176 RAERDELRVVADQIGTPSRRALIADITAQLLRQRTAETSGTWHLTAAGQTSWHGFAEAIF 235 Query: 226 E------ILGWDVRVKPINSSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEALGEYLK 278 E +L RV PI +++ AKRP +S L EKL++ + + W+ L + Sbjct: 236 EEAVSAGLLPRAPRVVPITTADYPTPAKRPAYSRLSIEKLQRDFDIVLPEWRPGLQRVIA 295 Query: 279 E 279 E Sbjct: 296 E 296 >gb|AAB47841.1| (U61226) RfbC [Leptospira interrogans] Length = 306 Score = 118 bits (294), Expect = 6e-26 Identities = 89/297 (29%), Positives = 143/297 (47%), Gaps = 29/297 (9%) Query: 7 GANGQLGTDLVEVF---GEEAIPLTRKDLDVTDFESLKILKELKPEVIINTAAYVRVDDA 63 G NGQLG +L E F G EA+ R++ D+ D +S + + P ++++ AY VD A Sbjct: 6 GKNGQLGWELAERFKSNGLEAVGFGREEWDLADLDSAARILKDSPRILVHCGAYTAVDKA 65 Query: 64 ELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFD------GAKGEPYTEEDIPNP 117 E E A+K+N++ ++ + +YISTD+VFD G + + +P Sbjct: 66 ESDSENAYKINSLSVKKISEECLKRKIHLIYISTDFVFDANSETIGDTIRFWKPDSTLSP 125 Query: 118 INVYGASKYIGEIFTRN---YSKKYYIIRVASLYGKAGARGKGGNFVEWVIK--KANKGE 172 +YG SK GE + RN SK+ I+R + +Y G NF + ++K + + Sbjct: 126 KGIYGLSKAEGEKWIRNTFANSKQANIVRTSWVYS-----SHGNNFPKTIVKLLQDSNRH 180 Query: 173 ELRIVNDQFMSPTYTKDVAR----TLRELLRLRPSFGVYHMVNEGYCSWYEFTRAI---- 224 ELR++ DQ PT+ +A + +L+ + H N G SWY+F A+ Sbjct: 181 ELRVIEDQLGRPTWAGRLADFIIFLIYGILKGESYPEILHFSNSGVASWYDFALAVRDFS 240 Query: 225 --FEILGWDVRVKPINSSELKRLAKRPKFSALKNEKLEKIGLKMKHWKEALGEYLKE 279 F ++ + PI + A RP++S L E+ KI + HW+E L LKE Sbjct: 241 HSFSLIENLKPIYPIPTEGYPTPAPRPRYSILDLEETRKIFGVVPHWREDLTLCLKE 297 >pir||E82828 dTDP-4-keto-L-rhamnose reductase XF0258 [imported] - Xylella fastidiosa (strain 9a5c) >gi|9105073|gb|AAF83071.1|AE003879_6 (AE003879) dTDP-4-keto-L-rhamnose reductase [Xylella fastidiosa] Length = 302 Score = 118 bits (293), Expect = 7e-26 Identities = 91/295 (30%), Positives = 137/295 (45%), Gaps = 27/295 (9%) Query: 1 MRVAVIGANGQLGTDLVE-VFGEEAIPLTR-------KDLDVTDFESLKILKEL----KP 48 M V V GA GQ+G +L+ + G +TR ++ DF+ + L+ L +P Sbjct: 1 MTVLVFGAGGQIGQELLRSLSGRVVCAVTRSGRLPNGRECVQADFDRPETLRPLLDAQRP 60 Query: 49 EVIINTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEP 108 ++N AAY VD AE P+ F++NA +A G V+ STDYVFDG P Sbjct: 61 AQVVNAAAYTAVDRAESEPDVVFRINAQAPGVIAHWCARHGVPLVHYSTDYVFDGQGTSP 120 Query: 109 YTEEDIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKA 168 Y +D P+N+YGASK GE R I+R + +Y G NF+ +++ Sbjct: 121 YGVDDPVAPLNIYGASKLAGERAVRAAGGCSLILRTSWVYA-----AHGHNFLRTMLRLG 175 Query: 169 NKGEELRIVNDQFMSPTYTKDVARTLRELLR---LRPSFGVYHMVNEGYCSWYEFTRAIF 225 E L +V DQ +PT +A +LL G++H+ G SW+ F IF Sbjct: 176 ATSERLPVVADQIGTPTAAGLIADVTAQLLAGGGQSRHAGIWHLTATGQTSWHGFAEEIF 235 Query: 226 ---EILGWDVR---VKPINSSELKRLAKRPKFSALKNEKL-EKIGLKMKHWKEAL 273 + G +R V+ I S A+RP +S L L E G+ + W++ + Sbjct: 236 AQAQACGLMMRVPQVQAIASVGYPTAARRPAYSCLDTTALVETFGIVLPDWRQGV 290 >gb|AAD52187.1|AF144879_26 (AF144879) unknown [Leptospira interrogans] Length = 306 Score = 118 bits (292), Expect = 1e-25 Identities = 89/297 (29%), Positives = 143/297 (47%), Gaps = 29/297 (9%) Query: 7 GANGQLGTDLVEVF---GEEAIPLTRKDLDVTDFESLKILKELKPEVIINTAAYVRVDDA 63 G NGQLG +L E F G EA+ R++ D+ D +S + + P ++++ AY VD A Sbjct: 6 GKNGQLGWELAERFKSNGLEAVGFGREEWDLADLDSAARILKDSPRILVHCGAYTAVDKA 65 Query: 64 ELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFD------GAKGEPYTEEDIPNP 117 E E A+K+N++ ++ + +YISTD+VFD G + + +P Sbjct: 66 ESDSENAYKINSLSVKKISEECLKRKIHLIYISTDFVFDANSETIGDTIRFWKPDSTLSP 125 Query: 118 INVYGASKYIGEIFTRN---YSKKYYIIRVASLYGKAGARGKGGNFVEWVIK--KANKGE 172 +YG SK GE + RN SK+ IIR + +Y G NF + ++K + + Sbjct: 126 KGIYGLSKAEGEKWIRNTFANSKQANIIRTSWVYS-----SHGNNFPKTIVKLLQDSNRH 180 Query: 173 ELRIVNDQFMSPTYTKDVAR----TLRELLRLRPSFGVYHMVNEGYCSWYEFTRAI---- 224 ELR++ DQ PT+ +A + +L+ + H N G SWY+F A+ Sbjct: 181 ELRVIEDQLGRPTWAGRLADFIIFLIYGILKGESYPEILHFSNSGVASWYDFALAVRDFS 240 Query: 225 --FEILGWDVRVKPINSSELKRLAKRPKFSALKNEKLEKIGLKMKHWKEALGEYLKE 279 F ++ + PI + A RP++S L ++ KI + HW+E L LKE Sbjct: 241 HSFSLIENLKPIYPIPTEGYPTPAPRPRYSILDLDETRKIFGVVPHWREDLTLCLKE 297 >gb|AAD12970.1| (AF078135) RmlD [Leptospira borgpetersenii] Length = 306 Score = 117 bits (290), Expect = 2e-25 Identities = 91/298 (30%), Positives = 148/298 (49%), Gaps = 31/298 (10%) Query: 7 GANGQLGTDLVEVFGE---EAIPLTRKDLDVTDFESL-KILKELKPEVIINTAAYVRVDD 62 G +GQLG +L + F E+I +R++ D+TD +S+ KILK+ P+++++ AY VD Sbjct: 6 GKSGQLGWELTKRFKSLDLESIGFSREEWDLTDLDSVEKILKD-SPKILVHCGAYTAVDK 64 Query: 63 AELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFD------GAKGEPYTEEDIPN 116 AE E +K+N++ ++ + +YISTD+VFD G + + + Sbjct: 65 AESDSENVYKINSLSVKKISEECLKRKIHLIYISTDFVFDANSETIGDTIRFWKPDSTLS 124 Query: 117 PINVYGASKYIGEIFTRNY---SKKYYIIRVASLYGKAGARGKGGNFVEWVIK--KANKG 171 P +YG SK GE + +N SK+ I+R + +Y G NF + ++K + K Sbjct: 125 PKGIYGLSKAEGERWIQNIFADSKQANIVRTSWVYS-----SYGNNFPKTILKLLQDPKR 179 Query: 172 EELRIVNDQFMSPTYTKDVAR----TLRELLRLRPSFGVYHMVNEGYCSWYEFTRAI--- 224 EL+++ DQ PT+ +A + E+L+ + H N G SWY+F AI Sbjct: 180 TELKVIEDQLGRPTWAGRLADFIIFLIYEILKKGGYPEILHPSNSGIASWYDFAIAIRDI 239 Query: 225 ---FEILGWDVRVKPINSSELKRLAKRPKFSALKNEKLEKIGLKMKHWKEALGEYLKE 279 F ++ + PI + A RP++S L + KI + HWKE L LKE Sbjct: 240 SYSFSLIENLKPISPIPTESYPTAAPRPRYSILDLNETRKIFGPVPHWKEDLTLCLKE 297 >sp|P37778|RFBD_SHIFL DTDP-4-DEHYDRORHAMNOSE REDUCTASE (DTDP-4-KETO-L-RHAMNOSE REDUCTASE) (DTDP-6-DEOXY-L-MANNOSE DEHYDROGENASE) (DTDP-L-RHAMNOSE SYNTHETASE) >gi|541222|pir||S41535 rfbC protein - Shigella flexneri >gi|454899|emb|CAA50768.1| (X71970) rfbA [Shigella flexneri] Length = 300 Score = 114 bits (282), Expect = 1e-24 Identities = 84/299 (28%), Positives = 144/299 (48%), Gaps = 26/299 (8%) Query: 1 MRVAVIGANGQLGTDLVEVFGEEAIPLTRKDLDVTDFES--------LKILKELKPEVII 52 M + + G GQ+G +L L D+ TD+ + +K+++P+VI+ Sbjct: 1 MNILLFGKTGQVGWELQRALAPLG-NLIALDVHSTDYCGDFSNPEGVAETVKKIRPDVIV 59 Query: 53 NTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEE 112 N AA+ VD AE P A +NA + + ANE+GA ++ STDYVF G + E Sbjct: 60 NAAAHTAVDKAESEPNFAQLLNATCVEAIIKAANEVGAWVIHYSTDYVFPGNGDTAWLET 119 Query: 113 DIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGE 172 D P+NVYG +K +++ K+ I R + +Y GKG NF + +++ A E Sbjct: 120 DATAPLNVYGGTKLAWGKALQDHCGKHLIFRTSWVYA-----GKGNNFAKTMLRLAKDRE 174 Query: 173 ELRIVNDQFMSPTYTKD-VARTLRELLRLRPS----FGVYHMVNEGYCSWYEFTRAIFE- 226 L ++ DQF +PT D +A R + L + G+YH+V G +W+++ +F+ Sbjct: 175 TLAVITDQFGAPTGALDLLADCTRHAIWLAANKPEVAGLYHLVAGGTTTWHDYPALVFKE 234 Query: 227 --ILGWDVRVKPIN---SSELKRLAKRPKFSALKNEKLEK-IGLKMKHWKEALGEYLKE 279 G+++ + +N ++ A+ P L EK ++ L + W+ + L E Sbjct: 235 ARRAGFNLPLNKLNAVPTTAYPTPARGPHNFRLNTEKFQQNFALVLPDWQVGVKRMLNE 293 >emb|CAC13137.1| (AJ250139) dTDP-4-dehydrorhamnose reductase [Acetobacter xylinus] Length = 295 Score = 113 bits (281), Expect = 2e-24 Identities = 84/272 (30%), Positives = 132/272 (47%), Gaps = 21/272 (7%) Query: 3 VAVIGANGQLGTDLVEVFGEEAIP-LTRKDLDVTDFESL-KILKELKPEVIINTAAYVRV 60 + V G +GQL T L G E + + R D D ++ +I+ E PE ++N AA+ V Sbjct: 7 ILVTGGHGQLATALA---GHEGVMRVGRPDFDFDRPGTIDQIMAENTPEFVVNAAAWTAV 63 Query: 61 DDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNPINV 120 D AE E A + N G +A G ++ISTDYVF G KG PY E D +P +V Sbjct: 64 DAAETDAEGAARANHAGPARLAAACRARGIPLIHISTDYVFSGDKGSPYMETDPVDPRSV 123 Query: 121 YGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIVNDQ 180 YG++K GE I+R A +Y NFV +++ A + LR+V+DQ Sbjct: 124 YGSTKAAGEQAVLAAQPDSIILRTAWVYSPYNR-----NFVRTMVEAAARRPTLRVVSDQ 178 Query: 181 FMSPTYTKDVARTLRELLR-LRPS------FGVYHMVNEGYCSWYEFTRAIFEILGWDVR 233 +PT +A+T+ ++R +R + G+YH +G SWY+ A Sbjct: 179 IGNPTSADALAQTIMHIIRQIRETGWKADYAGIYHAAGQGATSWYDLACAAVAAAARHGN 238 Query: 234 ----VKPINSSELKRLAKRPKFSALKNEKLEK 261 ++PI +++ A+RP + L +L++ Sbjct: 239 PQPVMEPITTADWPTPARRPADARLDCTRLQE 270 >gb|AAK41127.1| dTDP-4-dehydrorhamnose reductase (rfbD-1) [Sulfolobus solfataricus] Length = 226 Score = 109 bits (271), Expect = 3e-23 Identities = 79/217 (36%), Positives = 119/217 (54%), Gaps = 15/217 (6%) Query: 47 KPEVIINTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKG 106 +P+VIINTAA VD E+ E+A+K+NA ++ R + + A +++STDYVFDG KG Sbjct: 9 RPDVIINTAAMTDVDKCEVEREKAYKINAEAVKHMVRASRVVEAYFIHVSTDYVFDGTKG 68 Query: 107 EPYTEEDIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIK 166 Y E+D+PNPIN YG +K +GE F +Y +IR + ++ R KG F +V K Sbjct: 69 N-YKEDDLPNPINYYGLTKLLGETFALSYDDS-LVIRTSGVF-----RHKG--FPVYVYK 119 Query: 167 KANKGEELRIVNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFE 226 +G+ + + SP + +A + ELL LR + G+ ++ E S YE I E Sbjct: 120 TLKEGKTV-FAYKGYYSPISARKLASAIEELLALRKT-GLLNVAGE-RISRYELALKIKE 176 Query: 227 ILGWDVRVKPINSSELKR-LAKRPKFSALKNEKLEKI 262 VK ++ E+K A+RP S+L K +KI Sbjct: 177 KFNLPGEVKEVD--EVKGWTARRPFDSSLDYSKAKKI 211 >emb|CAB57472.1| (Y18930) dTDP-4-dehydrorhamnose reductase [Sulfolobus solfataricus] Length = 226 Score = 109 bits (271), Expect = 3e-23 Identities = 79/217 (36%), Positives = 119/217 (54%), Gaps = 15/217 (6%) Query: 47 KPEVIINTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKG 106 +P+VIINTAA VD E+ E+A+K+NA ++ R + + A +++STDYVFDG KG Sbjct: 9 RPDVIINTAAMTDVDKCEVEREKAYKINAEAVKHMVRASRVVEAYFIHVSTDYVFDGTKG 68 Query: 107 EPYTEEDIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIK 166 Y E+D+PNPIN YG +K +GE F +Y +IR + ++ R KG F +V K Sbjct: 69 N-YKEDDLPNPINYYGLTKLLGETFALSYDDS-LVIRTSGVF-----RHKG--FPVYVYK 119 Query: 167 KANKGEELRIVNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFE 226 +G+ + + SP + +A + ELL LR + G+ ++ E S YE I E Sbjct: 120 TLKEGKTV-FAYKGYYSPISARKLASAIEELLALRKT-GLLNVAGE-RISRYELALKIKE 176 Query: 227 ILGWDVRVKPINSSELKR-LAKRPKFSALKNEKLEKI 262 VK ++ E+K A+RP S+L K +KI Sbjct: 177 KFNLPGEVKEVD--EVKGWTARRPFDSSLDYSKAKKI 211 >emb|CAB56837.1| (AJ243721) dTDP-4-keto-6-deoxy-D-glucose 4-reductase [Homo sapiens] Length = 323 Score = 106 bits (261), Expect = 4e-22 Identities = 92/301 (30%), Positives = 146/301 (47%), Gaps = 26/301 (8%) Query: 2 RVAVIGANGQLGTDLVEVF----------GEEAIPLTRKDLDVTDFESLK-ILKELKPEV 50 RV V GA G LG + + F G + +++ D ++ I+ + +P V Sbjct: 19 RVLVTGATGLLGRAVHKEFQQNNWHAVGCGFRRARPKFEQVNLLDSNAVHHIIHDFQPHV 78 Query: 51 IINTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYT 110 I++ AA R D E P+ A ++N + N+A+ A +GA +YIS+DYVFDG PY Sbjct: 79 IVHCAAERRPDVVENQPDAASQLNVDASGNLAKEAAAVGAFLIYISSDYVFDGT-NPPYR 137 Query: 111 EEDIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEW-VIKKAN 169 EEDIP P+N+YG +K GE + ++R+ LYG+ + V + ++ +N Sbjct: 138 EEDIPAPLNLYGKTKLDGEKAVLENNLGAAVLRIPILYGEVEKLEESAVTVMFDKVQFSN 197 Query: 170 KGEELRIVNDQFMSPTYTKDVARTLRELLRLR---PSF-GVYHMVNEGYCSWYEFTRAIF 225 K + +F PT+ KDVA R+L R PS G +H + YE AI Sbjct: 198 KSANMDHWQQRF--PTHVKDVATVCRQLAEKRMLDPSIKGTFHWSGNEQMTKYEMACAIA 255 Query: 226 EILGW-DVRVKPINSSELKRLAKRPKFSALKNEKLEKIGLKMK-----HWKEALGEYLKE 279 + ++PI S + A+RP+ + L KLE +G+ + KE+L +L + Sbjct: 256 DAFNLPSSHLRPITDSPVLG-AQRPRNAQLDCSKLETLGIGQRTPFRIGIKESLWPFLID 314 Query: 280 K 280 K Sbjct: 315 K 315 >gi|11034825 dTDP-4-keto-6-deoxy-D-glucose 4-reductase; beta regulatory subunit of methionine adenosyltransferase [Homo sapiens] >gi|6815285|gb|AAF28477.1| (AF182814) methionine adenosyltransferase regulatory beta subunit [Homo sapiens] Length = 334 Score = 106 bits (261), Expect = 4e-22 Identities = 92/301 (30%), Positives = 146/301 (47%), Gaps = 26/301 (8%) Query: 2 RVAVIGANGQLGTDLVEVF----------GEEAIPLTRKDLDVTDFESLK-ILKELKPEV 50 RV V GA G LG + + F G + +++ D ++ I+ + +P V Sbjct: 30 RVLVTGATGLLGRAVHKEFQQNNWHAVGCGFRRARPKFEQVNLLDSNAVHHIIHDFQPHV 89 Query: 51 IINTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYT 110 I++ AA R D E P+ A ++N + N+A+ A +GA +YIS+DYVFDG PY Sbjct: 90 IVHCAAERRPDVVENQPDAASQLNVDASGNLAKEAAAVGAFLIYISSDYVFDGT-NPPYR 148 Query: 111 EEDIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEW-VIKKAN 169 EEDIP P+N+YG +K GE + ++R+ LYG+ + V + ++ +N Sbjct: 149 EEDIPAPLNLYGKTKLDGEKAVLENNLGAAVLRIPILYGEVEKLEESAVTVMFDKVQFSN 208 Query: 170 KGEELRIVNDQFMSPTYTKDVARTLRELLRLR---PSF-GVYHMVNEGYCSWYEFTRAIF 225 K + +F PT+ KDVA R+L R PS G +H + YE AI Sbjct: 209 KSANMDHWQQRF--PTHVKDVATVCRQLAEKRMLDPSIKGTFHWSGNEQMTKYEMACAIA 266 Query: 226 EILGW-DVRVKPINSSELKRLAKRPKFSALKNEKLEKIGLKMK-----HWKEALGEYLKE 279 + ++PI S + A+RP+ + L KLE +G+ + KE+L +L + Sbjct: 267 DAFNLPSSHLRPITDSPVLG-AQRPRNAQLDCSKLETLGIGQRTPFRIGIKESLWPFLID 325 Query: 280 K 280 K Sbjct: 326 K 326 >gb|AAK41975.1| dTDP-4-dehydrorhamnose reductase (rfbD-2) [Sulfolobus solfataricus] Length = 207 Score = 100 bits (246), Expect = 2e-20 Identities = 73/204 (35%), Positives = 111/204 (53%), Gaps = 15/204 (7%) Query: 60 VDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNPIN 119 VD E+ ++A+K+N+ ++ R + + ++ISTDYVFDG KG Y E++IPNPIN Sbjct: 4 VDKCEIEKDKAYKINSQAVKHIVRAGRVVDSYVIHISTDYVFDGNKGN-YKEDNIPNPIN 62 Query: 120 VYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIVND 179 YG SK +GEIF +Y + IIR + ++ R KG F +V K +G+ + + Sbjct: 63 YYGLSKLLGEIFASSYDES-LIIRTSGVF-----RNKG--FPIYVYKTLKEGKTV-LAFK 113 Query: 180 QFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFEILGWDVRVKPINS 239 + SP + +A + ELL LR + G+ H+ E S YE I E VK ++ Sbjct: 114 GYYSPISARKLALAIDELLDLRKT-GIIHVAGE-RISRYELAIKIKEKFNLPGEVKEVD- 170 Query: 240 SELKR-LAKRPKFSALKNEKLEKI 262 E+K +AKRP S+L K K+ Sbjct: 171 -EIKSWIAKRPYDSSLDISKARKL 193 >gb|AAC70777.1| (AF097519) dTDP-4-keto-L-rhamnose reductase [Klebsiella pneumoniae] Length = 296 Score = 96.7 bits (237), Expect = 3e-19 Identities = 70/227 (30%), Positives = 117/227 (50%), Gaps = 22/227 (9%) Query: 1 MRVAVIGANGQLGTDL---VEVFGEE-AIPLTRKDL--DVTDFESLK-ILKELKPEVIIN 53 M +++IG NGQ+G +L + G+ A+ K+L D+T+ E + ++ ++P+V++N Sbjct: 1 MNISLIGNNGQVGWELHRSLSFLGDVVAVDYFDKELCGDLTNLEGVAHTVRPVRPDVVVN 60 Query: 54 TAAY---VRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYT 110 AA+ R+ +P + GA E+GA+ V+ STDYVFDGA Sbjct: 61 AAAHSPWTRLKSIGSFPTCLIRQMGGGA---GGGVGELGALMVHYSTDYVFDGAGSHYRR 117 Query: 111 EEDIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANK 170 E++ P+NVYG +K GE+ + + ++ I R + +Y GA NF + +++ A + Sbjct: 118 EDEATGPLNVYGETKRAGELALQQGNPRHLIFRTSWVYATRGA-----NFAKTMLRLAGE 172 Query: 171 GEELRIVNDQFMSPT----YTKDVARTLRELLRLRPSFGVYHMVNEG 213 E L I++D +PT A +RE LR G YH+V G Sbjct: 173 KETLTIIDDLLWAPTGAELLADCTATAIRETLRNPALAGTYHLVASG 219 >pir||S35300 rfbG protein - Yersinia enterocolitica >gi|48591|emb|CAA79353.1| (Z18920) WbbW [Yersinia enterocolitica] Length = 289 Score = 90.9 bits (222), Expect = 2e-17 Identities = 78/284 (27%), Positives = 129/284 (44%), Gaps = 11/284 (3%) Query: 2 RVAVIGANGQLGTDLVEVFGE---EAIPLTRKDLDVTDFESL-KILKELKPEVIINTAAY 57 ++ + G G LG + + I R L+++ E++ + KP+VI++ AA Sbjct: 4 KILITGGTGMLGAYVTSALKDTDYNVIVTERNTLNLSVPEAIFSYITAEKPDVILHFAAE 63 Query: 58 VRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNP 117 VD E P A N + +A+ A GA +Y+S+ VF G Y E DIP P Sbjct: 64 TDVDLCEREPARAGIYNHLATEQIAQAAKFCGAWLLYLSSSNVFGGEGKLSYNELDIPLP 123 Query: 118 INVYGASKYIGEIFTRN-YSKKYYIIRVASLYGKAGARGKGGNFVEWVIKKANKGE-ELR 175 +N YG SK IGE RN + + IIR + G G K FV +I++ G ++ Sbjct: 124 MNYYGRSKLIGESSVRNACTNNHLIIRAGWMIG--GGPDKDHKFVGKIIQQIKAGSTSIK 181 Query: 176 IVNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEFTRAIFEILGWDVRVK 235 V+D+ S T + + + R + G H + G S ++ AI ++L + + Sbjct: 182 AVSDRLGSITSAMQLCNFIIWAINKRHT-GTLHFASSGTISRFDIACAIGDLLNFKGDII 240 Query: 236 PINSSELKRLAKRPKFSALKNEKLEKI--GLKMKHWKEALGEYL 277 P++SS A RP +++ + + K WK L +Y+ Sbjct: 241 PVHSSVFPLSAPRPYSEGIESIYMSILSDAPKPSLWKSDLAKYV 284 >pir||F75597 dTDP-4-rhamnose reductase-related protein - Deinococcus radiodurans (strain R1) >gi|6460559|gb|AAF12265.1|AE001862_91 (AE001862) dTDP-4-rhamnose reductase-related protein [Deinococcus radiodurans] Length = 247 Score = 86.6 bits (211), Expect = 3e-16 Identities = 51/145 (35%), Positives = 81/145 (55%), Gaps = 3/145 (2%) Query: 2 RVAVIGANGQLGTDLVEVFGEEAIPLTRKDLDVTDFESLKILKELKPEVIINTAAYVRVD 61 ++ + G +G+LGT+L V E P + + + L +++ +P++I++ AAY V Sbjct: 8 KMLLTGGSGRLGTELRSVIPEIVAPSSAEMNLTAAAQVLAVVQRERPDIIVHAAAYTNVG 67 Query: 62 DAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNP-INV 120 AE E + N +G NVA AN +GA V+ISTDYVF G +G Y E D P P +N Sbjct: 68 GAEKDREACWNANVVGTRNVAAAANAVGAKLVHISTDYVFSGEEG-GYHESDTPGPVVNY 126 Query: 121 YGASKYIGEIFTRNYSKKYYIIRVA 145 Y +K + E R ++K+ I+R + Sbjct: 127 YSLTKLVAEEAAR-AAQKHLILRTS 150 >emb|CAB56751.1| (X56616) putative dTDP-4-dehydrorhamnose reductase [Acidianus ambivalens] Length = 232 Score = 83.1 bits (202), Expect = 3e-15 Identities = 61/198 (30%), Positives = 109/198 (54%), Gaps = 15/198 (7%) Query: 21 GEEAIPLTRK-DLDVTDFESLKILKELKPEVIINTAAYVRVDDAELYPEEAFKVNAIGAL 79 GE A LT D + +S K + E KPE++I+T ++D P + +N A+ Sbjct: 8 GELARALTNAIDDEFIFIDSPKKVYETKPEIVIHT-----LEDNSNNPS-MWNLNTWFAI 61 Query: 80 NVARIANEIGAINVYISTDYVFDGAKGEPYTEEDIPNPINVYGASKYIGEIFTRNYSKKY 139 N+A+ AN+IG++NVY ST ++DG +G Y+E P+P+N YG +K +GE + Y Sbjct: 62 NIAKAANKIGSLNVYFSTFMIYDGKRGY-YSETSTPSPLNYYGMTKLVGETAIASLG-NY 119 Query: 140 YIIRVASLYGKAGARGKGGNFVEWVIKKANKGEELRIVNDQFMSPTYTKDVARTLRELLR 199 I+R+ ++Y + RG + ++ +IKK + + ++SP KDVA ++ LL+ Sbjct: 120 LILRLGAVYSPS-YRGILFHIIKALIKKG----IAKCNTNLYLSPISVKDVAYAVKYLLK 174 Query: 200 LRPSFGVYHMVNEGYCSW 217 + + GV ++ + + + Sbjct: 175 -KDARGVINLAGKRFSEY 191 >gb|AAD12954.1| (AF078135) unknown [Leptospira borgpetersenii] Length = 298 Score = 72.2 bits (174), Expect = 7e-12 Identities = 65/296 (21%), Positives = 132/296 (43%), Gaps = 37/296 (12%) Query: 2 RVAVIGANGQLGTDLVEVFGEEA---IPLTRKDLDVTDF-------------------ES 39 ++ V+G +G LG + V E A + T + ++ F E Sbjct: 6 KILVLGVSGMLGNAVFRVLSENAEFEVQGTIRSIEYLRFFTKAESERITSNMDVLNEDEL 65 Query: 40 LKILKELKPEVIINTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDY 99 L++ +KP++++N ++ P +N++ ++ + IGA + ISTD Sbjct: 66 LRLFSNIKPDIVVNCVGIIKQQKLSKDPITVLPINSLLPHRLSNLCKLIGARLILISTDC 125 Query: 100 VFDGAKGEPYTEEDIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGN 159 VF+G KG YTE D P+ ++YG SK IGEI ++ + +R + + + + + Sbjct: 126 VFNGQKGN-YTETDTPDAEDLYGRSKEIGEIREESH---VFTVRTSIIGHELNS---NYS 178 Query: 160 FVEWVIKKANKGEELRIVNDQFMSPTYTKDVARTLRELLRLRPS-FGVYHMVNEGYCSWY 218 V+W + ++ E++ F S + ++A ++ ++ P +G+YH V+ S + Sbjct: 179 LVDWFL---SQNGEVKGYKKAFFSGLPSCEIAEIIKTVIIPNPKLYGLYH-VSSDPISKF 234 Query: 219 EFTRAIFEILGWDVRVKPINSSELKRLAKRPKF---SALKNEKLEKIGLKMKHWKE 271 + + E+ G + ++ + R KF ++ K + + MK +KE Sbjct: 235 DLLSLVGEVYGKNNKILESEEVIVDRSLDSTKFRKETSYKPLPWKSLIFLMKKYKE 290 >gb|AAD52171.1|AF144879_10 (AF144879) unknown [Leptospira interrogans] Length = 298 Score = 72.2 bits (174), Expect = 7e-12 Identities = 63/296 (21%), Positives = 133/296 (44%), Gaps = 37/296 (12%) Query: 2 RVAVIGANGQLGTDLVEVFGEEA---IPLTRKDLDVTDF-------------------ES 39 ++ V+G +G LG + V + A + T + ++ F E Sbjct: 6 KILVLGVSGMLGNAVFRVLSDSAEFEVQGTIRSIEYLRFFTKAESERITSNMDVLNEDEL 65 Query: 40 LKILKELKPEVIINTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDY 99 L++ +KP++++N ++ P +N++ ++ + +GA + ISTD Sbjct: 66 LRLFSNIKPDIVVNCVGIIKQQKLAKDPITVLPINSLLPHRLSNLCKLVGARLILISTDC 125 Query: 100 VFDGAKGEPYTEEDIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGN 159 VF+G KG YTE D+P+ ++YG SK IGE+ + + +R + + + + + Sbjct: 126 VFNGQKGN-YTETDMPDAEDLYGRSKEIGEVRDEPH---VFTVRTSIIGHELNS---NYS 178 Query: 160 FVEWVIKKANKGEELRIVNDQFMSPTYTKDVARTLRELLRLRPS-FGVYHMVNEGYCSWY 218 V+W + ++ E+R F S + ++A ++ ++ P +G+YH ++ S + Sbjct: 179 LVDWFL---SQNGEVRGYKKAFFSGLPSYEIAEIIKTVIIPNPKLYGLYH-ISSDPISKF 234 Query: 219 EFTRAIFEILGWDVRVKPINSSELKRLAKRPKF---SALKNEKLEKIGLKMKHWKE 271 + + E+ G + ++ + R KF ++ K + + L MK +KE Sbjct: 235 DLLSLVGEVYGKNNKILESEEVIVDRSLDSTKFRKETSYKPLPWKNLILLMKKYKE 290 >pir||A71183 probable UDP-glucose 4-epimerase - Pyrococcus horikoshii >gi|3258173|dbj|BAA30856.1| (AP000007) 306aa long hypothetical UDP-glucose 4-epimerase [Pyrococcus horikoshii] Length = 306 Score = 71.8 bits (173), Expect = 9e-12 Identities = 76/305 (24%), Positives = 135/305 (43%), Gaps = 42/305 (13%) Query: 3 VAVIGANGQLGTDLVEVFGEEAIPLTRKDL-----------------DVTDFESL-KILK 44 + + G G +G+ L E +E + +L DV D+ES+ +++ Sbjct: 6 IVITGGAGFIGSHLAEALKDENDVIIIDNLYSGRIENIPEGVKFIRADVRDYESIAEVIS 65 Query: 45 ELKPEVIINTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYVFDGA 104 E + + + AA + V ++ P +VN IG +NV R ++ ++ S+ V+ Sbjct: 66 EA--DYVFHEAAQISVKESIEDPVFTEEVNVIGTINVLRALSQGDGKLIFASSAAVYGEP 123 Query: 105 KGEPYTEEDIPNPINVYGASKYIGEIFTRNYSKKY----YIIRVASLYGKAGARGKGGNF 160 K P TE+ + NPI+ YG +K E + R Y Y I+R ++YG + G Sbjct: 124 KELPITEDTLTNPISPYGITKLAAEHYCRVYQSLYGIPVVILRYFNVYGPRQSSAYAG-V 182 Query: 161 VEWVIKKANKGEELRIVND--QFMSPTYTKDVARTLRELLRLRPSFG-VYHMVNEGYCSW 217 + +++A KGE L I D Q Y KDV + + R + G ++++ + Sbjct: 183 ISIFLERAIKGEPLIIFGDGKQTRDFIYVKDVVEANILVAKKRSANGRIFNVATGKETTI 242 Query: 218 YEFTRAIFEILGWDVRVKPINSSELKRLAKRP---KFSALKNEKLEKIGLKMKHWKEALG 274 E I ++ +SS + RP + S K E+++K+G K ++ +L Sbjct: 243 LELAMKIIDMTS--------SSSSILFYPPRPGDIRRSVAKIERIKKLGFKPRY---SLE 291 Query: 275 EYLKE 279 E LKE Sbjct: 292 EGLKE 296 >gb|AAK42337.1| dTDP-4-dehydrorhamnose reductase (rfbD-3) [Sulfolobus solfataricus] Length = 255 Score = 70.2 bits (169), Expect = 3e-11 Identities = 54/192 (28%), Positives = 105/192 (54%), Gaps = 11/192 (5%) Query: 41 KILKELKPEVIINTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYV 100 K+++E KP+VII+T + + ++ P A+ N A+N+AR ++ G++NV++S+ + Sbjct: 34 KVIRE-KPDVIIHTFE-IPIFESNANPPLAWSFNTWYAINIARAGSKAGSVNVFLSSFLI 91 Query: 101 FDGAKGEPYTEEDIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNF 160 +DG +G Y E + P+P+N YG +K +GE + Y ++RV +L+ RG F Sbjct: 92 YDGKRGF-YKEHNTPHPLNYYGLTKLVGESSIISLG-NYLVLRVGALF-SLSYRG----F 144 Query: 161 VEWVIKKANKGEELRIVNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEF 220 + IK + G+ L+ + ++S +A+ ++ LL + + GV + V S ++ Sbjct: 145 LFPFIKASTMGKVLKCNKNFYISIIDLNTLAKVIK-LLIDKEARGVIN-VGSNRVSLFDI 202 Query: 221 TRAIFEILGWDV 232 + +I G +V Sbjct: 203 CSYLSDIFGNEV 214 >pir||S74068 hypothetical protein c0137 - Sulfolobus solfataricus >gi|1707767|emb|CAA69439.1| (Y08256) orf c01037 [Sulfolobus solfataricus] Length = 255 Score = 70.2 bits (169), Expect = 3e-11 Identities = 54/192 (28%), Positives = 105/192 (54%), Gaps = 11/192 (5%) Query: 41 KILKELKPEVIINTAAYVRVDDAELYPEEAFKVNAIGALNVARIANEIGAINVYISTDYV 100 K+++E KP+VII+T + + ++ P A+ N A+N+AR ++ G++NV++S+ + Sbjct: 34 KVIRE-KPDVIIHTFE-IPIFESNANPPLAWSFNTWYAINIARAGSKAGSVNVFLSSFLI 91 Query: 101 FDGAKGEPYTEEDIPNPINVYGASKYIGEIFTRNYSKKYYIIRVASLYGKAGARGKGGNF 160 +DG +G Y E + P+P+N YG +K +GE + Y ++RV +L+ RG F Sbjct: 92 YDGKRGF-YKEHNTPHPLNYYGLTKLVGESSIISLG-NYLVLRVGALF-SLSYRG----F 144 Query: 161 VEWVIKKANKGEELRIVNDQFMSPTYTKDVARTLRELLRLRPSFGVYHMVNEGYCSWYEF 220 + IK + G+ L+ + ++S +A+ ++ LL + + GV + V S ++ Sbjct: 145 LFPFIKASTMGKVLKCNKNFYISIIDLNTLAKVIK-LLIDKEARGVIN-VGSNRVSLFDI 202 Query: 221 TRAIFEILGWDV 232 + +I G +V Sbjct: 203 CSYLSDIFGNEV 214 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.318 0.139 0.400 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 106227182 Number of Sequences: 2977 Number of extensions: 4593100 Number of successful extensions: 15914 Number of sequences better than 1.0e-10: 81 Number of HSP's better than 0.0 without gapping: 49 Number of HSP's successfully gapped in prelim test: 32 Number of HSP's that attempted gapping in prelim test: 15645 Number of HSP's gapped (non-prelim): 81 length of query: 283 length of database: 189,106,746 effective HSP length: 55 effective length of query: 228 effective length of database: 156,189,961 effective search space: 35611311108 effective search space used: 35611311108 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.7 bits) S2: 164 (68.3 bits)