BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0809 (napA-4) DE:Na+/H+ antiporter (napA-4)
(390 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||C75103 na+/h+ antiporter (napa-4) PAB0809 - Pyrococcus abys... 738 0.0
pir||H71083 probable Na+/H+-exchanging protein - Pyrococcus hori... 650 0.0
pir||H71455 probable Na+/H+-exchanging protein - Pyrococcus hori... 183 3e-45
pir||C75016 na+/h+ antiporter (napa-3) PAB1247 - Pyrococcus abys... 172 5e-42
sp|P26235|NAPA_ENTHR NA(+)/H(+) ANTIPORTER >gi|282287|pir||A4211... 163 4e-39
gb|AAB40041.1| (U17283) putative spore germination apparatus pro... 158 1e-37
gb|AAF91326.1|AF246294_2 (AF246294) GerN [Bacillus cereus] 157 2e-37
pir||C75201 na+/h+ antiporter (napa-1) PAB0084 - Pyrococcus abys... 152 7e-36
pir||F71234 probable Na+/H+-exchanging protein - Pyrococcus hori... 152 9e-36
emb|CAA51756.1| (X73329) Na/H antiporter homolog [Lactococcus la... 148 1e-34
pir||E70380 Na+/H+-exchanging protein - Aquifex aeolicus >gi|298... 147 2e-34
pir||S74414 Na+/H+-exchanging protein sll0689 - Synechocystis sp... 142 6e-33
pir||C82955 probable sodium/proton antiporter PA5529 [imported] ... 140 3e-32
gb|AAK41390.1| Na(+)/H(+) antiporter [Sulfolobus solfataricus] 135 1e-30
pir||B64459 Na+/H+-exchanging protein - Methanococcus jannaschii... 127 2e-28
dbj|BAB02053.1| (AB022219) Na+/H+ exchangeing protein-like [Arab... 126 5e-28
dbj|BAB11467.1| (AB005233) Na+/H+ antiporter-like protein [Arabi... 122 6e-27
pir||S74951 Na+/H+-exchanging protein slr1595 - Synechocystis sp... 121 2e-26
pir||T05602 hypothetical protein F9D16.170 - Arabidopsis thalian... 120 3e-26
pir||T45912 hypothetical protein F5K20.20 - Arabidopsis thaliana... 120 4e-26
gb|AAD22684.1|AC007063_10 (AC007063) putative Na+/H+ antiporter ... 119 6e-26
dbj|BAB06563.1| (AP001516) Na+/H+ antiporter [Bacillus halodurans] 113 4e-24
pir||F70155 Na+/H+ antiporter (napA) homolog - Lyme disease spir... 107 3e-22
gb|AAF24561.1|AC007764_3 (AC007764) F22C12.7 [Arabidopsis thaliana] 107 3e-22
pir||B71038 probable Na+/H+-exchanging protein - Pyrococcus hori... 104 1e-21
emb|CAB45049.1| (AL078635) putative integral membrane ion antipo... 104 1e-21
pir||S76532 hypothetical protein - Synechocystis sp. (strain PCC... 103 3e-21
gb|AAF26906.1|AF210843_3 (AF210843) unknown [Sorangium cellulosum] 103 4e-21
pir||C75176 na+/h+ antiporter (napa-2) PAB0390 - Pyrococcus abys... 100 4e-20
gi|6322367 Yjl094cp [Saccharomyces cerevisiae] >gi|731972|sp|P40... 96 9e-19
emb|CAC12310.1| (AL445066) Na+/H+ antiporter related protein [Th... 96 9e-19
sp|P39830|YBAL_ECOLI HYPOTHETICAL 59.4 KD PROTEIN IN GSK-FSR INT... 95 1e-18
pir||A69845 Na+/H+ antiporter homolog yjbQ - Bacillus subtilis >... 95 1e-18
gi|11497833 Na+/H+ antiporter (napA-1) [Archaeoglobus fulgidus] ... 92 8e-18
pir||D71642 glutathione-regulated potassium-efflux system protei... 90 3e-17
pir||C70474 Na+/H+-exchanging protein - Aquifex aeolicus >gi|298... 89 9e-17
gb|AAF69026.1| (AF182516) unknown [Pseudomonas putida] 88 2e-16
gb|AAD10158.1| (AC005917) putative potassium/proton antiporter [... 87 3e-16
pir||E82956 probable potassium efflux transporter PA5518 [import... 87 3e-16
gb|AAK40705.1| Na(+)/H(+) antiporter [Sulfolobus solfataricus] 87 4e-16
pir||T50062 Probable K+/H+-antiporter [imported] - fission yeast... 87 4e-16
pir||F82595 glutathione-regulated potassium efflux system protei... 85 2e-15
pir||A81330 probable glutathione-regulated potassium-efflux syst... 82 1e-14
pir||G69819 Na+/H+ antiporter homolog yhaU - Bacillus subtilis >... 82 1e-14
pir||B82056 glutathione-regulated potassium-efflux system protei... 81 3e-14
pir||G75282 probable glutathione-regulated potassium-efflux syst... 79 8e-14
sp|P45522|KEFB_ECOLI GLUTATHIONE-REGULATED POTASSIUM-EFFLUX SYST... 78 1e-13
pir||C83496 glutathione-regulated potassium-efflux system protei... 78 2e-13
gb|AAD01191.1| (AF003382) KEA1 [Arabidopsis thaliana] 77 3e-13
pir||A72473 probable Na+/H+ antiporter APE2426 - Aeropyrum perni... 77 4e-13
gb|AAF78418.1|AC009273_24 (AC009273) Identical to K efflux antip... 76 5e-13
gb|AAC60780.1| (U46859) RosB [Yersinia enterocolitica (type 0:8)] 76 9e-13
pir||C81997 probable glutathione-regulated potassium-efflux syst... 76 9e-13
gi|11498844 Na+/H+ antiporter (napA-2) [Archaeoglobus fulgidus] ... 75 1e-12
pir||B81225 glutathione-regulated potassium-efflux system protei... 75 2e-12
pir||G70337 Na+/H+-exchanging protein - Aquifex aeolicus >gi|298... 74 3e-12
sp|P03819|KEFC_ECOLI GLUTATHIONE-REGULATED POTASSIUM-EFFLUX SYST... 73 4e-12
pir||G64578 glutathione-regulated potassium-efflux system protei... 72 1e-11
pir||T00576 Na+/H+-exchanging protein homolog T27E13.2 - Arabido... 72 1e-11
emb|CAB44437.1| (AJ242913) glutathione-gated K efflux system [Kl... 72 1e-11
pir||F70591 probable kefB protein - Mycobacterium tuberculosis (... 71 3e-11
pir||C71934 glutathione-regulated potassium-efflux system protei... 69 6e-11
pir||T01227 glutathione-regulated potassium-efflux system protei... 69 8e-11
gb|AAA84962.1| (U37008) KefC [Myxococcus xanthus] 69 8e-11
>pir||C75103 na+/h+ antiporter (napa-4) PAB0809 - Pyrococcus abyssi (strain
Orsay) >gi|5458640|emb|CAB50128.1| (AJ248286) Na+/H+
antiporter (napA-4) [Pyrococcus abyssi]
Length = 390
Score = 738 bits (1884), Expect = 0.0
Identities = 390/390 (100%), Positives = 390/390 (100%)
Query: 1 MNYIFDLSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFG 60
MNYIFDLSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFG
Sbjct: 1 MNYIFDLSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFG 60
Query: 61 LIMMMLYMGLTSNFSAISRNKVKATIVATLGVAFSFILGFSTVYFIERNMIAALFVGITL 120
LIMMMLYMGLTSNFSAISRNKVKATIVATLGVAFSFILGFSTVYFIERNMIAALFVGITL
Sbjct: 61 LIMMMLYMGLTSNFSAISRNKVKATIVATLGVAFSFILGFSTVYFIERNMIAALFVGITL 120
Query: 121 GNTAIEVTSGVLVRERVKKEISSVLMGAAFADDIIAVYLIGLLTGITQGSFSLYPMVVLT 180
GNTAIEVTSGVLVRERVKKEISSVLMGAAFADDIIAVYLIGLLTGITQGSFSLYPMVVLT
Sbjct: 121 GNTAIEVTSGVLVRERVKKEISSVLMGAAFADDIIAVYLIGLLTGITQGSFSLYPMVVLT 180
Query: 181 IKIVVFIVATLLISEFVFKRSARFYNVVKDLHVFFTFTIILTFMLAFLAEDIGLNQIIGA 240
IKIVVFIVATLLISEFVFKRSARFYNVVKDLHVFFTFTIILTFMLAFLAEDIGLNQIIGA
Sbjct: 181 IKIVVFIVATLLISEFVFKRSARFYNVVKDLHVFFTFTIILTFMLAFLAEDIGLNQIIGA 240
Query: 241 YLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGLMFQPNVREISV 300
YLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGLMFQPNVREISV
Sbjct: 241 YLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGLMFQPNVREISV 300
Query: 301 LMIALLYLAAILGKLIGCGLGMLLFGSSLRDAIIVGVGMGGRGSLELAILKLGLEKGLIN 360
LMIALLYLAAILGKLIGCGLGMLLFGSSLRDAIIVGVGMGGRGSLELAILKLGLEKGLIN
Sbjct: 301 LMIALLYLAAILGKLIGCGLGMLLFGSSLRDAIIVGVGMGGRGSLELAILKLGLEKGLIN 360
Query: 361 ESLFATIVIVSMLTALSTPIFFRGVIRKLS 390
ESLFATIVIVSMLTALSTPIFFRGVIRKLS
Sbjct: 361 ESLFATIVIVSMLTALSTPIFFRGVIRKLS 390
>pir||H71083 probable Na+/H+-exchanging protein - Pyrococcus horikoshii
>gi|3257347|dbj|BAA30030.1| (AP000004) 390aa long
hypothetical Na(+)/H(+) antiporter [Pyrococcus
horikoshii]
Length = 390
Score = 650 bits (1658), Expect = 0.0
Identities = 325/390 (83%), Positives = 366/390 (93%)
Query: 1 MNYIFDLSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFG 60
M+YIFDLSILLVVAKSLEWLLKK+G+HPIIAHILTGIILGPFGL+IV P+ ELKVLGEFG
Sbjct: 1 MSYIFDLSILLVVAKSLEWLLKKKGIHPIIAHILTGIILGPFGLSIVLPTSELKVLGEFG 60
Query: 61 LIMMMLYMGLTSNFSAISRNKVKATIVATLGVAFSFILGFSTVYFIERNMIAALFVGITL 120
LIMMMLYMGLTSNFSAISRNKVKA++VA GVAFSFILGF TVYF+E+++IAALFVGITL
Sbjct: 61 LIMMMLYMGLTSNFSAISRNKVKASVVAMFGVAFSFILGFLTVYFLEKSLIAALFVGITL 120
Query: 121 GNTAIEVTSGVLVRERVKKEISSVLMGAAFADDIIAVYLIGLLTGITQGSFSLYPMVVLT 180
GNTAIEVTSGVLVRERVKK+ISSVLMGAAFADDIIAVYLIG+LTGITQG S +V LT
Sbjct: 121 GNTAIEVTSGVLVRERVKKDISSVLMGAAFADDIIAVYLIGILTGITQGGISGLSLVFLT 180
Query: 181 IKIVVFIVATLLISEFVFKRSARFYNVVKDLHVFFTFTIILTFMLAFLAEDIGLNQIIGA 240
IKIV+FI+ L++SEFVFKRS RFYN+++DLH+FFTFTI+LTF LAF+A+DIGLNQIIGA
Sbjct: 181 IKIVIFILGVLMLSEFVFKRSTRFYNIIRDLHIFFTFTIVLTFTLAFIAQDIGLNQIIGA 240
Query: 241 YLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGLMFQPNVREISV 300
YLAGLTISRLRERKDPMVITRIKLNELI ELE+VL+EFFIPLFF+YVGLMF PNVR+IS+
Sbjct: 241 YLAGLTISRLRERKDPMVITRIKLNELIEELEIVLVEFFIPLFFVYVGLMFNPNVRDISI 300
Query: 301 LMIALLYLAAILGKLIGCGLGMLLFGSSLRDAIIVGVGMGGRGSLELAILKLGLEKGLIN 360
L+I LLY +A+LGKLIGCGLGM +FGSS+RDAIIVG+GMGGRGSLELAILKLGLEKGLI+
Sbjct: 301 LLILLLYASAVLGKLIGCGLGMKIFGSSIRDAIIVGIGMGGRGSLELAILKLGLEKGLID 360
Query: 361 ESLFATIVIVSMLTALSTPIFFRGVIRKLS 390
E +FAT+VIVSMLTALSTP+ FR +RKLS
Sbjct: 361 EGIFATVVIVSMLTALSTPVLFRYTVRKLS 390
>pir||H71455 probable Na+/H+-exchanging protein - Pyrococcus horikoshii
>gi|3256692|dbj|BAA29375.1| (AP000001) 380aa long
hypothetical Na(+)/H(+) antiporter [Pyrococcus
horikoshii]
Length = 380
Score = 183 bits (460), Expect = 3e-45
Identities = 107/385 (27%), Positives = 203/385 (51%), Gaps = 13/385 (3%)
Query: 1 MNYIFDLSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFG 60
MN + +L+I+LVVAK +L+ K G + ++ GII+GP L IV+ S+E++ L E G
Sbjct: 1 MNVLLELAIILVVAKLFGYLMVKLGFPAALGQLIGGIIIGPSLLNIVEYSQEVRFLAELG 60
Query: 61 LIMMMLYMGLTSNFSAISRNKVKATIVATLGVAFSFILGFSTVYFIERNMIAALFVGITL 120
+I+++ GL ++ + A IVAT+GV F+LG+ +AALF+G L
Sbjct: 61 VIILLFLAGLETDVEEFKHVGLSAFIVATMGVFVPFLLGYLIAIVYGYRSLAALFLGGIL 120
Query: 121 GNTAIEVTSGVLVR-ERVKKEISSVLMGAAFADDIIAVYLIGLLTGI-TQGSFSLYPMVV 178
T++ +T+ +L+ ++++ ++ + ++ AA DD++ + ++ +L + ++G ++ + +
Sbjct: 121 TATSVGLTTSILMEMKKLRTKVGTTILAAAIVDDVLGIIILTILVAMSSRGRVEIFDIEI 180
Query: 179 LTIKIVVFIVATLLISEFVFKRSARFYNVVKDLHVFFTFTIILTFMLAFLAEDIGLNQII 238
+ ++++F + + I + K + TF I++ + A+LAE L I
Sbjct: 181 ILAEVIIFFLLGIFIGHPIVKEVLMLSEKITLPETVTTFAIVIMLLFAYLAEKFQLAGIT 240
Query: 239 GAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGLMFQPNVREI 298
GAYLAGL +S K ++ ++ + FIP+F + +G+ V
Sbjct: 241 GAYLAGLLVSMSEGSK-----------KVTDKMMTIGYSLFIPIFLVSIGIETDIKVLAT 289
Query: 299 SVLMIALLYLAAILGKLIGCGLGMLLFGSSLRDAIIVGVGMGGRGSLELAILKLGLEKGL 358
+ + + L AI+GK+ GCG G L+ +A+ VG+GM R + L I +GL++G+
Sbjct: 290 AGVFAIVYSLIAIIGKIQGCGFGALVTKFKPAEALQVGIGMIPRMEVALIIANVGLKEGI 349
Query: 359 INESLFATIVIVSMLTALSTPIFFR 383
+ A V + ++T L TP +
Sbjct: 350 LTRGTLAIPVTMVVVTTLVTPFLLK 374
>pir||C75016 na+/h+ antiporter (napa-3) PAB1247 - Pyrococcus abyssi (strain
Orsay) >gi|5459083|emb|CAB50569.1| (AJ248288) Na+/H+
antiporter (napA-3) [Pyrococcus abyssi]
Length = 380
Score = 172 bits (432), Expect = 5e-42
Identities = 106/392 (27%), Positives = 205/392 (52%), Gaps = 17/392 (4%)
Query: 1 MNYIFDLSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFG 60
M +L+I+LV+AK +L + G + +L G+I+GP L +V+ E+++L E G
Sbjct: 1 MEVFLELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELG 60
Query: 61 LIMMMLYMGLTSNFSAISRNKVKATIVATLGVAFSFILGFSTVYFIERNMIAALFVGITL 120
++M++ GL ++ + A IVA +GV F+LG+ + ALF G L
Sbjct: 61 VVMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVL 120
Query: 121 GNTAIEVTSGVLV-RERVKKEISSVLMGAAFADDIIAVYLIGLLTGI-TQGSFSLYPMVV 178
T++ +T+ +L+ ++++ ++ + ++ AA DD++ + ++ LL + ++G + + +
Sbjct: 121 TATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEI 180
Query: 179 LTIKIVVFIVATLLISEFVFKRSARFYNVVKDLHVFFTFTIILTFMLAFLAEDIGLNQII 238
+ +++ +F + +LI + K + TF I++ + A+LAE L I
Sbjct: 181 ILLEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQLAGIT 240
Query: 239 GAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGLMFQPNVREI 298
GAYLAGL +S + ++ ++ + FIP+F + +G+ + ++R +
Sbjct: 241 GAYLAGLLVSMTEGSR-----------KITDKIMTIGYSLFIPIFLVSIGI--ETDIRVL 287
Query: 299 S-VLMIALLY-LAAILGKLIGCGLGMLLFGSSLRDAIIVGVGMGGRGSLELAILKLGLEK 356
+ + AL+Y L A++GK+IGCG G L+ +AI VG+GM R + L I +GL++
Sbjct: 288 THAGVFALVYSLIAVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKE 347
Query: 357 GLINESLFATIVIVSMLTALSTPIFFRGVIRK 388
G++ A V + ++T L TP + K
Sbjct: 348 GILTRGDLAVPVTMVVITTLITPFLLKWAFSK 379
>sp|P26235|NAPA_ENTHR NA(+)/H(+) ANTIPORTER >gi|282287|pir||A42111 Na+/H+-exchanging
protein NapA - Enterococcus hirae
>gi|148316|gb|AAA24781.1| (M81961) NaH-antiporter
protein [Enterococcus hirae]
Length = 383
Score = 163 bits (408), Expect = 4e-39
Identities = 109/391 (27%), Positives = 200/391 (50%), Gaps = 13/391 (3%)
Query: 1 MNYIFDLSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFG 60
M +I L ++LV + ++ G+ +I +L G++LG GL V P+ + E G
Sbjct: 1 MEFIGILCLILVATTIGSHISRRFGIPAVIGQLLVGVLLGQAGLGWVHPNILVHDFSEIG 60
Query: 61 LIMMMLYMGLTSNFSAISRNKVKATIVATLGVAFSFILGFSTVYFIERNMIAALFVGITL 120
+I++M GL S+ S + + VA LG+ F G+ T + A+F GI L
Sbjct: 61 VILLMFLAGLESDLSLLKKYFKPGMFVALLGILFPVFFGWLTGEAFQVANNEAIFFGIIL 120
Query: 121 GNTAIEVTSGVLVRERV-KKEISSVLMGAAFADDIIAVYLIGL-LTGITQGSFSLYPMVV 178
T++ ++ VL V + S ++GA+ DDI+ V ++ L+ +T S S P+ +
Sbjct: 121 AATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLVLSFSLSFLTGKSTSNLPLPL 180
Query: 179 LTIKIVVFIVATLLISEFVFKRSARFYNVVKDLHVFFTFTIILTFMLAFLAEDIGLNQII 238
L ++ + + + L+ +++ + ++++ +++LA+ IGL+ +I
Sbjct: 181 LLLEQLFYFLFIFLLVKWIAPFLMSLAEKIYANSAIIIMSLVICLGMSYLADLIGLSSVI 240
Query: 239 GAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGLMFQPNVREI 298
GA+ AG+ +S+ T++K +E+ + +E + FIP+FF+ VGL +
Sbjct: 241 GAFFAGIAVSQ----------TKVK-HEVYNNVEALGYAVFIPVFFVSVGLEVDFSKFSE 289
Query: 299 SVLMIALLYLAAILGKLIGCGLGMLLFGSSLRDAIIVGVGMGGRGSLELAILKLGLEKGL 358
+L I +L L AIL KLIG +G S A++VG GM RG + L IL++G + L
Sbjct: 290 QILFILILTLVAILTKLIGGYIGAKFSSFSSNSALMVGAGMISRGEMALIILQIGQQSNL 349
Query: 359 INESLFATIVIVSMLTALSTPIFFRGVIRKL 389
I ++ +VIV +L+ L +P+ + +K+
Sbjct: 350 IENHYYSPLVIVVLLSTLISPLILKYFTKKV 380
>gb|AAB40041.1| (U17283) putative spore germination apparatus protein [Bacillus
megaterium] >gi|1589214|prf||2210362A grmA gene
[Bacillus megaterium]
Length = 386
Score = 158 bits (395), Expect = 1e-37
Identities = 105/391 (26%), Positives = 188/391 (47%), Gaps = 13/391 (3%)
Query: 1 MNYIFDLSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFG 60
M ++ L+++L K L + G ++ +L GIILGP L + + + E G
Sbjct: 1 MEFVLSLALILFATKIAGHLSVRLGQPSVLGKLLIGIILGPAVLGWIHNDQFVHYFSEIG 60
Query: 61 LIMMMLYMGLTSNFSAISRNKVKATIVATLGVAFSFILGFSTVYFIERNMIAALFVGITL 120
++++M GL ++ + RN A VA LG+ FI GF +LF+G+ L
Sbjct: 61 VLLLMFLAGLETDLEQLKRNWKAAFAVAVLGIILPFIGGFGVGELFGLGATYSLFIGVLL 120
Query: 121 GNTAIEVTSGVLV-RERVKKEISSVLMGAAFADDIIAVYLIGLLTGITQGSFSLYPMVVL 179
T++ +T VL R+ S ++GAA DD++ V L+ ++ G+ + +L
Sbjct: 121 CATSVSITVQVLKDMNRLNSREGSTILGAAVVDDVLVVVLLAIMISFL-GTGEEVSLGLL 179
Query: 180 TIKIVVFIVATLLISEFVFKRSARFYNVVKDLHVFFTFTIILTFMLAFLAEDIGLNQIIG 239
K ++F + +L V + + +K + + + F + A+ +G+ IIG
Sbjct: 180 VGKKLIFFIGAVLAGWLVVPKVLDWLTNLKVTEPVVSIGLAICFGYVYFADLMGMAGIIG 239
Query: 240 AYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGLMFQPNVREIS 299
A+ AG+ IS+ R + + S++E + F+P+FF+ +GL
Sbjct: 240 AFAAGIAISQTSYR-----------HTIESKVEPIAYAVFVPVFFVSIGLNVSFEGVGDQ 288
Query: 300 VLMIALLYLAAILGKLIGCGLGMLLFGSSLRDAIIVGVGMGGRGSLELAILKLGLEKGLI 359
+ I LL + A++ KL+G LG + G S R ++++G GM RG + L I GL++ L+
Sbjct: 289 IGFILLLSVIAVITKLVGGALGAKVTGFSTRSSLLIGSGMVSRGEVALIIAATGLQESLL 348
Query: 360 NESLFATIVIVSMLTALSTPIFFRGVIRKLS 390
F + VIV ++T L P + +I+ S
Sbjct: 349 LPEYFTSAVIVIIITTLVAPPLIKYIIQSES 379
>gb|AAF91326.1|AF246294_2 (AF246294) GerN [Bacillus cereus]
Length = 387
Score = 157 bits (394), Expect = 2e-37
Identities = 105/379 (27%), Positives = 189/379 (49%), Gaps = 16/379 (4%)
Query: 3 YIFDLSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFGLI 62
+ F ++++L+ K L + G ++ ++ GI++GP L ++ SE L L G+I
Sbjct: 5 FFFQIALILLSTKLAGDLSVRLGQPSVLGKLIVGIVIGPAVLGWIENSELLTQLSNVGVI 64
Query: 63 MMMLYMGLTSNFSAISRNKVKATIVATLGVAFSFILGFSTVYFIERNMIAALFVGITLGN 122
++M GL ++ ++ N+ + VA G+ F+ G+ + + A+F+G+ L
Sbjct: 65 LLMFMAGLETDLEELNANRNSSLAVALGGIILPFVGGYVSGLVMGMEQGNAVFLGLLLCA 124
Query: 123 TAIEVTSGVLVRE--RVKKEISSVLMGAAFADDIIAVYLIGLLTGITQGSFSLYPMVVLT 180
T++ ++ L R+ ++K S+ ++GAA DDI+ V L+ MV+L
Sbjct: 125 TSVSISVQTL-RDLGKMKTRESTTMLGAAVFDDILVVILLAFAMSFLGTDDVNLTMVIL- 182
Query: 181 IKIVVFIVATLLISEFVFKRSARFYNVVKDLHVFFTFTIILTFMLAFLAEDIGLNQIIGA 240
K VVF + +LI R+ + ++ + +I+ F A+ E +G+ IIGA
Sbjct: 183 -KKVVFFASIILIGWKGVPAIMRWLSPLRVSESIVSAALIICFSFAYFGELLGIAGIIGA 241
Query: 241 YLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGLMFQPNVREISV 300
+ AG+ IS+ + +E+ ++E + F+P+FF+ +G+ + +
Sbjct: 242 FAAGIAISQTNYK-----------HEVEKKVEPIAYAMFVPVFFVSIGMNITFDGIGNQI 290
Query: 301 LMIALLYLAAILGKLIGCGLGMLLFGSSLRDAIIVGVGMGGRGSLELAILKLGLEKGLIN 360
I L + A+L KLIGCG G + G + + I+G GM RG + L I GL GL+
Sbjct: 291 WFILALTVIAVLTKLIGCGFGARMTGFDAKSSAIIGAGMVSRGEVALIIAGTGLSSGLLA 350
Query: 361 ESLFATIVIVSMLTALSTP 379
+ F IVIV +LT + TP
Sbjct: 351 QDYFTAIVIVVILTTMITP 369
>pir||C75201 na+/h+ antiporter (napa-1) PAB0084 - Pyrococcus abyssi (strain
Orsay) >gi|5457567|emb|CAB49058.1| (AJ248283) Na+/H+
antiporter (napA-1) [Pyrococcus abyssi]
Length = 375
Score = 152 bits (380), Expect = 7e-36
Identities = 100/386 (25%), Positives = 190/386 (48%), Gaps = 20/386 (5%)
Query: 1 MNYIFDLSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFG 60
M + L+++L VAK W+ ++ ++ I+ G+I+G +++ +E + G
Sbjct: 1 METLLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMG----LLIERNEIIVEFANLG 56
Query: 61 LIMMMLYMGLTSNFSAISRNKVKATIVATLGVAFSFILGFSTVY-FIERNMIAALFVGIT 119
++M++ GL S+F R + +VA++GV F+F+ GF Y F + AL G
Sbjct: 57 VLMLLFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAYPFFDFG--TALLYGAI 114
Query: 120 LGNTAIEVTSGVLVR-ERVKKEISSVLMGAAFADDIIAVYLIGLLTG-ITQGSFSLYPMV 177
+ T++ +T VL+ +++ + + ++ AA DD++ + ++ ++ + +GS +V
Sbjct: 115 MTPTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVHYDVIV 174
Query: 178 VLTIKIVVFIVATLLISEFVFKRSARFYNVVKDLHVFFTFTIILTFMLAFLAEDIGLNQI 237
+ +++ F+ L + V + R + V +F I+ + A+LAE + L I
Sbjct: 175 EVLLEVAGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHLNLASI 234
Query: 238 IGAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGLMFQPNVRE 297
+GAYL GL+I + +K + + V+ FIP+FF+ VG+ P
Sbjct: 235 LGAYLIGLSIGQTSYKK-----------RIEGPMNVIGYSIFIPVFFVEVGMRIDPRFLF 283
Query: 298 ISVLMIALLYLAAILGKLIGCGLGMLLFGSSLRDAIIVGVGMGGRGSLELAILKLGLEKG 357
+ L + A++ K+IGCGLG L R +I +G+GM R +ELA++ + G
Sbjct: 284 EAKTFAFLYAVFAMISKVIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELAMISTAMAAG 343
Query: 358 LINESLFATIVIVSMLTALSTPIFFR 383
+ + + + LT L TPI R
Sbjct: 344 VAGSDVLTVAMTMVFLTTLITPIMLR 369
>pir||F71234 probable Na+/H+-exchanging protein - Pyrococcus horikoshii
>gi|3256522|dbj|BAA29205.1| (AP000001) 375aa long
hypothetical Na(+)/H(+) antiporter [Pyrococcus
horikoshii]
Length = 375
Score = 152 bits (379), Expect = 9e-36
Identities = 102/393 (25%), Positives = 193/393 (48%), Gaps = 22/393 (5%)
Query: 1 MNYIFDLSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFG 60
M + L+ILL VAK W+ +K ++ IL GI++G I++ +E + G
Sbjct: 1 METLLLLAILLAVAKFSGWIFEKFNQPIVLGQILAGILMG----LIIERNEIIIEFANLG 56
Query: 61 LIMMMLYMGLTSNFSAISRNKVKATIVATLGVAFSFILGFSTVY-FIERNMIAALFVGIT 119
++M++ G+ S+ + +VA +GV F+FI GF Y F + A+ G
Sbjct: 57 VLMLLFLAGIESDLEEFKKVGKPGILVAGVGVLFAFIFGFIVAYPFFDFG--TAMLYGAV 114
Query: 120 LGNTAIEVTSGVLVR-ERVKKEISSVLMGAAFADDIIAVYLIGL-LTGITQGSFSLYPMV 177
+ T++ +T VL+ +++ + ++ AA DD++ + ++ + ++ + +GS ++
Sbjct: 115 MTPTSVSITVKVLMELGKLRTREGTTILAAAVIDDVLGILVLTIVISTLREGSVHYDIIL 174
Query: 178 VLTIKIVVFIVATLLISEFVFKRSARFYNVVKDLHVFFTFTIILTFMLAFLAEDIGLNQI 237
+ +++ F+ L I + + R + + TF ++ + A+LAE + L I
Sbjct: 175 KILLEVAGFLAVFLYIGPVFMEDAFRRLSKIDLPEATTTFAVVFLVLFAYLAEHLNLASI 234
Query: 238 IGAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGLMFQPNVRE 297
+GAYL GL+I + +K + + + FIPLFF+ VG+ P
Sbjct: 235 LGAYLIGLSIGQTSYKK-----------RIEDHMNTLGYSIFIPLFFVDVGMRIDPRFL- 282
Query: 298 ISVLMIALLY-LAAILGKLIGCGLGMLLFGSSLRDAIIVGVGMGGRGSLELAILKLGLEK 356
+ + ALLY L A+L K+IGCGLG L + ++ +G+GM R +ELA++ +
Sbjct: 283 LQAKVFALLYALIAMLSKVIGCGLGAYLANFDWKSSLKIGIGMIPRLGVELAMITTAMAS 342
Query: 357 GLINESLFATIVIVSMLTALSTPIFFRGVIRKL 389
G+ + + + LT L TP+ + + + L
Sbjct: 343 GIAGSDVLTVAMTMVFLTTLVTPLLLKRIYQIL 375
>emb|CAA51756.1| (X73329) Na/H antiporter homolog [Lactococcus lactis]
Length = 379
Score = 148 bits (369), Expect = 1e-34
Identities = 105/392 (26%), Positives = 191/392 (47%), Gaps = 20/392 (5%)
Query: 1 MNYIFDLSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFG 60
MN I L+I+L+ + ++ + +I +L GI++ P L +V L+V+ E G
Sbjct: 1 MNDILQLTIVLIASLIATLASRRLKIPAVIGQMLVGILIAPSVLGLVHSGHVLEVMSEIG 60
Query: 61 LIMMMLYMGLTSNFSAISRNKVKATIVATLGVAFSFILGFSTVYFIERNMIAALFVGITL 120
+I++M GL S+ + + +N + +VA GV I+ + M + F GI
Sbjct: 61 VILLMFLAGLESDLTVLKKNFKASMLVAIGGVIVPLIVFGLVAFSFGYGMSTSFFYGIVF 120
Query: 121 GNTAIEVTSGVLVR-ERVKKEISSVLMGAAFADDIIAVYLIGLLTGITQGSFSLYPMVVL 179
T++ +T VL ++ S+++GAA DDI+AV ++ + T G +
Sbjct: 121 AATSVSITVEVLQEYGKLSTRAGSIILGAAVVDDILAVLILSIFTSFKNGGSGTHLFFQF 180
Query: 180 TIKIVVFIVATLLISEFVFKRSARFYNVVKDLHVFFTFTI---ILTFMLAFLAEDIGLNQ 236
++++ F A L + V K RF+ V+ L + TI I+ L+ LA+ +G++
Sbjct: 181 LLELLFF--AFLFV---VHKLIPRFWKFVQKLPIANKNTIVALIICLGLSLLADSVGMSA 235
Query: 237 IIGAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGLMFQPNVR 296
+IG++ AGL IS+ K+ E S + V+ FIP+FF+ + + Q +
Sbjct: 236 VIGSFFAGLAISQTE--------VSHKIEEYTSAIGYVI---FIPVFFVLIAISVQFDSL 284
Query: 297 EISVLMIALLYLAAILGKLIGCGLGMLLFGSSLRDAIIVGVGMGGRGSLELAILKLGLEK 356
+I L L AIL K I S +++++G GM RG + L + ++GL
Sbjct: 285 IHHPWIILLFTLLAILTKFIPAYFVGKSNKLSTGESMLIGTGMISRGEMALIVAQIGLTS 344
Query: 357 GLINESLFATIVIVSMLTALSTPIFFRGVIRK 388
+I + +++ +VIV +L + P + V++K
Sbjct: 345 AIITDEVYSELVIVIILATVLAPFLIKLVLKK 376
>pir||E70380 Na+/H+-exchanging protein - Aquifex aeolicus
>gi|2983453|gb|AAC07034.1| (AE000714) Na(+)/H(+)
antiporter [Aquifex aeolicus]
Length = 408
Score = 147 bits (367), Expect = 2e-34
Identities = 110/390 (28%), Positives = 195/390 (49%), Gaps = 12/390 (3%)
Query: 7 LSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFGLIMMML 66
L+ILL AK + +K G+ P++ + G+ILG L ++ SE +KVL E G+I+++
Sbjct: 22 LAILLFSAKLFGSIFRKLGIPPVLGEVTAGVILGQSVLGLIPLSEAIKVLAELGVILLLF 81
Query: 67 YMGLTSNFSAISRNKVKATIVATLGVAFSFILGF-STVYFIERNMIAALFVGITLGNTAI 125
+GL ++ + + R + +T+VA +G A F GF + YF +++A+LF+G L T+I
Sbjct: 82 EVGLEADINMLMRVGLWSTLVAIVGAALPFAGGFIVSYYFFGLDLVASLFMGGALTATSI 141
Query: 126 EVTSGVLV-RERVKKEISSVLMGAAFADDIIAVYLIGLLTGITQGSFSLYPMVVLTIKIV 184
+T VL + K+ + +++GAA DDI+ V ++ L ++ + T+ ++
Sbjct: 142 GITVRVLTDLNKHKERFAQIVLGAAVLDDIMGVIILAALYEFSKTKAVHFD---TTVNLI 198
Query: 185 VFIVATLLISEFVFKRSARFYNV----VKDLHVFFTFTIILTFMLAFLAEDIGLNQIIGA 240
+ I+ LI+ FV A+ ++ +D+ + + L + A+ A G I+G+
Sbjct: 199 IHILMFFLIAPFVANVLAKLLSIAARKTQDMDLIPASIMALILLAAYSAHKFGSPSILGS 258
Query: 241 YLAGLTISRLRERKDPMVITRI--KLNELISELEVVLLEFFIPLFFIYVGLMFQPNVREI 298
+ AGL +SR R + R+ KL + E L+ P+FF+ VGL +
Sbjct: 259 FTAGLALSR-RFVIPFAAMLRLDEKLLHKVEESITPLVWVMAPIFFVSVGLALNLKAIDF 317
Query: 299 SVLMIALLYLAAILGKLIGCGLGMLLFGSSLRDAIIVGVGMGGRGSLELAILKLGLEKGL 358
S A I+ +IG L + SL++ +G M RG + L + G
Sbjct: 318 SSPEFWTFSSALIVVAIIGKVLAGFVAPGSLKEKASIGFSMLPRGEVGLIFAEFGRSFKA 377
Query: 359 INESLFATIVIVSMLTALSTPIFFRGVIRK 388
INE +A IV V +T L PI + ++++
Sbjct: 378 INEVEYAVIVFVVAVTTLIAPIVLKLLLKE 407
>pir||S74414 Na+/H+-exchanging protein sll0689 - Synechocystis sp. (strain PCC
6803) >gi|1001188|dbj|BAA10332.1| (D64001)
NaH-antiporter protein [Synechocystis sp.]
Length = 461
Score = 142 bits (355), Expect = 6e-33
Identities = 96/348 (27%), Positives = 176/348 (49%), Gaps = 29/348 (8%)
Query: 50 SEELKVLGEFGLIMMMLYMGLTSNFSAISRNKVKATIVATLGVAFSFILG---FSTVYFI 106
SE + V+ E G+I+++ +GL SN + R +A IVA +GV F LG T++ +
Sbjct: 113 SEVISVISELGVIILLFEIGLESNLKELIRVGPQAAIVAVVGVVTPFSLGTIGLMTIFGV 172
Query: 107 ERNMIAALFVGITLGNTAIEVTSGVLVR-ERVKKEISSVLMGAAFADDIIAVYLIGLLTG 165
I A+F G L T+I +T+ VL R+ +++GAA DDI+ + ++ ++
Sbjct: 173 AA--IPAIFAGAALTATSIGITAKVLAEINRLSSNEGQIIIGAAVLDDILGIIVLAVVGS 230
Query: 166 ITQ-GSFSLYPMVVLTIKIVVFIVATLLISEFVFKRSARFYNVVKDLHVFFTFTIILTFM 224
+ + G + ++ L + F+V ++LI + N +K +I + F+
Sbjct: 231 LVKTGEIQISNIIYLILSATGFVVGSILIGRLLSPFYVSLVNRMKTRGQLLLVSICVAFV 290
Query: 225 LAFLAEDIGLNQIIGAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFF 284
L+++A+ + L I+G++ AGL ++ +R+D + E + L +FF+P+FF
Sbjct: 291 LSYIAQIVQLEAILGSFAAGLILAETEKRED------------LEEQILPLADFFVPVFF 338
Query: 285 IYVGLMFQPNVREISV-------LMIALLYLAAILGKLIGCGLGMLLFGSSLRDAIIVGV 337
+ VG +V +V ++ A L L AI+GK++ G LFG S + + +GV
Sbjct: 339 VCVGAKTDVSVLNPAVPANREGLIIAAFLILVAIVGKVV---TGFTLFGKSELNKLAIGV 395
Query: 338 GMGGRGSLELAILKLGLEKGLINESLFATIVIVSMLTALSTPIFFRGV 385
GM RG + L +G G ++ + A I+++ ++T P + R V
Sbjct: 396 GMIPRGEVGLVFAGVGAASGALDPATDAAIIVMVIVTTFVAPPWLRAV 443
>pir||C82955 probable sodium/proton antiporter PA5529 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9951867|gb|AAG08914.1|AE004965_6 (AE004965) probable
sodium/proton antiporter [Pseudomonas aeruginosa]
Length = 585
Score = 140 bits (349), Expect = 3e-32
Identities = 95/389 (24%), Positives = 185/389 (47%), Gaps = 20/389 (5%)
Query: 1 MNYIFDLSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGP----FGLAIVKPSEELKVL 56
+++I DL+++++VA + L + ++ +I+ G I+GP FGL + + +K L
Sbjct: 4 VDFIQDLAVIMLVAGVVTILFHRLRQPVVLGYIVAGFIIGPHTPPFGL--IHDEDTIKTL 61
Query: 57 GEFGLIMMMLYMGLTSNFSAISRNKVKATIVATLGVAFSFILGFSTVYFIERNMIAALFV 116
E G+I +M +GL + + + A I A L + +GF F E + + +LF+
Sbjct: 62 AELGVIFLMFCLGLEFSLRKLFQVGATAFIAAFLEIVLMIWIGFEIGRFFEWSTMDSLFL 121
Query: 117 GITLGNTAIEVTSGVLVRERVKKE-ISSVLMGAAFADDIIAVYLIGLLTGIT-QGSFSLY 174
G L ++ + L ++K E + ++ G +DI+ + +I LL+GI GS
Sbjct: 122 GAILAISSTTIIVKALGDLKMKNERFAQLIFGVLIVEDILGIGIIALLSGIAVSGSVETG 181
Query: 175 PMVVLTIKIVVFIVATLLISEFVFKRSARFYNVVKDLHVFFTFTIILTFMLAFLAEDIGL 234
+ K+ +F++ L++ + R + + + + L F L +
Sbjct: 182 EVFSTVGKLSLFMIVALVVGILLVPRLLAYVAKFESNEMLLVTVLGLCFGFCLLVVKLEY 241
Query: 235 NQIIGAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGLMFQPN 294
+ ++GA+L G ++ R+ +++ LI + + F +FF+ +GL+ P
Sbjct: 242 SMVLGAFLIGAIMAESRQL--------VQIERLIEPVR----DMFSAIFFVAIGLLIDPK 289
Query: 295 VREISVLMIALLYLAAILGKLIGCGLGMLLFGSSLRDAIIVGVGMGGRGSLELAILKLGL 354
+ IAL+ +A +LGK+ CG+G + G+ R ++ VG+G+ G I LG+
Sbjct: 290 ILVEYAWPIALITVAVVLGKMFSCGMGAFIAGNDGRTSLRVGMGLSQIGEFSFIIAALGM 349
Query: 355 EKGLINESLFATIVIVSMLTALSTPIFFR 383
+ ++ L+ V VS +T L TP R
Sbjct: 350 TLKVTSDFLYPVAVAVSAITTLLTPYLIR 378
>gb|AAK41390.1| Na(+)/H(+) antiporter [Sulfolobus solfataricus]
Length = 391
Score = 135 bits (336), Expect = 1e-30
Identities = 99/402 (24%), Positives = 191/402 (46%), Gaps = 39/402 (9%)
Query: 4 IFDLSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPF----------GLAIVKPSEEL 53
+FD+SI +++A+ L L++K G+ +I +L G+I+GP+ G ++ + +
Sbjct: 8 LFDVSIFILLAEILSSLVQKYGLPKLIGELLAGMIIGPYALGSLLNQLLGFPLIGINSYI 67
Query: 54 KVLGEFGLIMMMLYMGLTSNFSAISRNKVKATIVATLGVAFSFILGFSTVYFIERNMIAA 113
+ L EF +I+++ GL + I + + + AT G F + Y + +A
Sbjct: 68 EFLAEFSVILLIFASGLEHGIAPIKSSGILGFLGATFGALLPFFAAYY-FYISSFGLDSA 126
Query: 114 LFVGITLGNTAIEVTSGVLVRERVKKEISSVLMGAAFADDIIAVYLIGLLTGITQG---- 169
L +G +G T++ + ++ ++K + + ++ +A ADD++ + L+ ++ I QG
Sbjct: 127 LILGTAMGATSLAAVASIIEEGKLKGKGINFMVSSAAADDVVDLLLLSVVIAILQGESTS 186
Query: 170 --SFSLYPMVVLTIKIVVFIVATLLISEFVFKRSARFYNVVKDLHVFFTFTIILTFMLAF 227
S SL + ++ I +V+ +V+ +LI + + S ++ F + + F L
Sbjct: 187 VTSISLKIIALVVIWVVILVVSIILIPKITDRISDKYIE---------EFPLAVLFGLTL 237
Query: 228 LAEDIGLNQIIGAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYV 287
L +G + II A++AG+ + + N I E+ LL F PLFF+Y+
Sbjct: 238 LMVSLGYSPIISAFVAGVAFANSVK------------NSKIKEISSTLLSVFGPLFFVYI 285
Query: 288 GLMFQPNVREISVLMIAL-LYLAAILGKLIGCGLGMLLFGSSLRDAIIVGVGMGGRGSLE 346
G ++ ++++L L A + K +G L + + + A V +GM RG
Sbjct: 286 GAEVNFLTLNLNTVILSLELTAIATIFKWLGIFPFALAYLRNAKAANTVALGMVPRGETG 345
Query: 347 LAILKLGLEKGLINESLFATIVIVSMLTALSTPIFFRGVIRK 388
L I LGL +N+ F IV +S+ T L F+ +K
Sbjct: 346 LVIASLGLSYNALNQEEFEGIVFMSIFTTLIGSALFKIYAKK 387
>pir||B64459 Na+/H+-exchanging protein - Methanococcus jannaschii
>gi|1591911|gb|AAB99281.1| (U67568) NA(+)/H(+)
antiporter (napA) [Methanococcus jannaschii]
Length = 388
Score = 127 bits (316), Expect = 2e-28
Identities = 92/391 (23%), Positives = 193/391 (48%), Gaps = 23/391 (5%)
Query: 2 NYIFDLSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFGL 61
+Y + I+L + + LLKK + I + ++ GII+GP+GL I++ E LK+L +FG
Sbjct: 3 SYYYVFFIILSIIFIVPNLLKKFNIPAITSIMIAGIIIGPYGLNILQVDETLKILADFGA 62
Query: 62 IMMMLYMGLTSNFSAISRNKVKATIVATLGVAFSFILGFSTVYFIERNMIAALFVGITLG 121
IM+M GL + + + + I++ + + G+ ++ I +L +
Sbjct: 63 IMLMFLAGLEVDNETLKQEFKNSLILSLFSLLIPGVGGYLIGQYLGLGFIGSLLYAVIFA 122
Query: 122 NTAIEVTSGVLVR-ERVKKEISSVLMGAAFADDIIAVYLIGLLTGITQGSFSLYPMVVLT 180
+ ++ + +L + VK + ++++ A D+ + L+ ++ + G ++ ++ T
Sbjct: 123 SHSVAIVYAILEELKMVKTRLGTIILSATIIVDLFTLLLLSVVIKLGIGGENVGTFLLET 182
Query: 181 IKIVVFIVATLLISEFVFKRSARFYNVVKDLHV-FFTFTIILTFMLAFLAEDIGLNQIIG 239
V + LL++ + S V + LH + + + F+ + E IG++ I+G
Sbjct: 183 ----VLYIGVLLLA--IPSLSKNILGVFEKLHAQRIHYVLFIIFIAIIVGEVIGIHPIVG 236
Query: 240 AYLAGLTISRLRERKDPMVITRIKLNELISE-LEVVLLEFFIPLFFIYVGLMFQPNVREI 298
A++ G+ +S +T+ + +EL+++ L + FFIP+FF+ +G+ + N+R I
Sbjct: 237 AFICGVAVSE--------ALTKEEHDELLNKNLNAIGYGFFIPIFFLVLGM--ETNIRVI 286
Query: 299 ----SVLMIALLYLAAILGKLIGCGLGMLLFGSSLRDAIIVGVGMGGRGSLELAILKLGL 354
++ ++ + ++A+ K I + + + G I G+ + S L +G
Sbjct: 287 FNLSNLELLLITLISAVALKFISGFIALRILGFDRIKNTIGGLLTVPKISASLVAASIGR 346
Query: 355 EKGLINESLFATIVIVSMLTALSTPIFFRGV 385
E GLI +F TIV +S++TA TPI + +
Sbjct: 347 ELGLIGNEIFVTIVALSVITATITPIVVKHI 377
>dbj|BAB02053.1| (AB022219) Na+/H+ exchangeing protein-like [Arabidopsis thaliana]
Length = 800
Score = 126 bits (313), Expect = 5e-28
Identities = 104/404 (25%), Positives = 201/404 (49%), Gaps = 42/404 (10%)
Query: 4 IFDLSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLAIVK-------PSEELKVL 56
I + +++V + L + LK +IA I+ GI+LGP L K P + L VL
Sbjct: 36 ILQIVLVVVFTRLLAYFLKPLKQPRVIAEIIGGILLGPSALGRSKAYLDTIFPKKSLTVL 95
Query: 57 ---GEFGLIMMMLYMGLTSNFSAISRNKVKATIVATLGVAFSFILGFSTVYFIERNMIAA 113
GL+ + +GL +F+AI + K+ ++A G++ FI+G T + + +
Sbjct: 96 DTLANIGLLFFLFLVGLELDFAAIKKTGKKSLLIAIAGISLPFIVGVGTSFVLSATISKG 155
Query: 114 L-------FVGITLGNTAIEVTSGVLVRERV-KKEISSVLMGAAFADDIIAVYLIGLLTG 165
+ F+G+ L TA V + +L ++ +I + M AA +D+ A L+ L
Sbjct: 156 VDQLPFIVFMGVALSITAFPVLARILAELKLLTTDIGRMAMSAAGVNDVAAWILLALAIA 215
Query: 166 I----TQGSFSLYPMVVLTIKIVVFIVATLLISEFVFKRSARFYNVVKDLHVFFTFTIIL 221
+ T S++ ++ T ++ +VA + ++ +R VK+L+V T T++L
Sbjct: 216 LSGDGTSPLVSVWVLLCGTGFVIFAVVAIKPLLAYMARRCPEG-EPVKELYVCVTLTVVL 274
Query: 222 TFMLAFLAEDIGLNQIIGAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIP 281
+F+ + IG++ + GA++ G+ + E ++T K+ +L+S L +P
Sbjct: 275 A--ASFVTDTIGIHALFGAFVVGIVAPK--EGPFCRILTE-KIEDLVSGL-------LLP 322
Query: 282 LFFIYVGLMFQPNVREI----SVLMIALLYLAAILGKLIGCGLGMLLFGSSLRDAIIVGV 337
L+F GL + +V I S ++ L+ L GK++G +L R+A+ +G
Sbjct: 323 LYFAASGL--KTDVTTIRGAQSWGLLVLVILTTCFGKIVGTVGSSMLCKVPFREAVTLGF 380
Query: 338 GMGGRGSLELAILKLGLEKGLINESLFATIVIVSMLTA-LSTPI 380
M +G +EL +L +G ++ ++N+ FA +V++++ T ++TPI
Sbjct: 381 LMNTKGLVELIVLNIGKDRKVLNDQAFAILVLMALFTTFITTPI 424
>dbj|BAB11467.1| (AB005233) Na+/H+ antiporter-like protein [Arabidopsis thaliana]
Length = 810
Score = 122 bits (304), Expect = 6e-27
Identities = 102/405 (25%), Positives = 198/405 (48%), Gaps = 44/405 (10%)
Query: 4 IFDLSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLAIVK-------PSEELKVL 56
I + I++V+ + L +LL+ +IA ++ GI+LGP L K P + L VL
Sbjct: 35 ILQIVIVIVLTRVLAYLLRPLRQPRVIAEVIGGIMLGPSLLGRSKAFLDAVFPKKSLTVL 94
Query: 57 ---GEFGLIMMMLYMGLTSNFSAISRNKVKATIVATLGVAFSFILGFSTVYFIERNMIAA 113
GL+ + GL + A+ R KA +A G+ F LG + + ++ +
Sbjct: 95 ETLANLGLLFFLFLAGLEIDTKALRRTGKKALGIALAGITLPFALGIGSSFVLKATISKG 154
Query: 114 L-------FVGITLGNTAIEVTSGVLVRERV-KKEISSVLMGAAFADDIIAVYLIGLLTG 165
+ F+G+ L TA V + +L ++ EI + M AA +D+ A L+ L
Sbjct: 155 VNSTAFLVFMGVALSITAFPVLARILAELKLLTTEIGRLAMSAAAVNDVAAWILLALAIA 214
Query: 166 ITQGSFSLYPMVVLTIKI--VVFIVATLLISEFVFK---RSARFYNVVKDLHVFFTFTII 220
++ + S P+V L + + F++ I +F+ R +++ ++ T ++
Sbjct: 215 LSGSNTS--PLVSLWVFLSGCAFVIGASFIIPPIFRWISRRCHEGEPIEETYICATLAVV 272
Query: 221 LTFMLAFLAEDIGLNQIIGAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFI 280
L + F+ + IG++ + GA++ G+ I + + P L+ ++E ++ F+
Sbjct: 273 L--VCGFITDAIGIHSMFGAFVVGVLIPK----EGPFA------GALVEKVEDLVSGLFL 320
Query: 281 PLFFIYVGLMFQPNVREI----SVLMIALLYLAAILGKLIGCGLGMLLFGSSLRDAIIVG 336
PL+F+ GL + NV I S ++ L+ A GK++G L F +R+AI +G
Sbjct: 321 PLYFVASGL--KTNVATIQGAQSWGLLVLVTATACFGKILGTLGVSLAFKIPMREAITLG 378
Query: 337 VGMGGRGSLELAILKLGLEKGLINESLFATIVIVSMLTA-LSTPI 380
M +G +EL +L +G ++ ++N+ FA +V++++ T ++TP+
Sbjct: 379 FLMNTKGLVELIVLNIGKDRKVLNDQTFAIMVLMALFTTFITTPV 423
>pir||S74951 Na+/H+-exchanging protein slr1595 - Synechocystis sp. (strain PCC
6803) >gi|1652066|dbj|BAA16991.1| (D90902) Na/H
antiporter [Synechocystis sp.]
Length = 410
Score = 121 bits (300), Expect = 2e-26
Identities = 104/403 (25%), Positives = 186/403 (45%), Gaps = 47/403 (11%)
Query: 6 DLSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLAIVKPSEE-----------LK 54
++ +++ +A+ + L + P+I I+ GI+LGP L ++ P+ E L
Sbjct: 12 NIIVIIGLARLIGLLFARFQQPPVIGEIIAGIMLGPSLLGLLSPALEKSFFPATTQPFLY 71
Query: 55 VLGEFGLIMMMLYMGLTSNFSAISRNKVKATIVATLGVAFSFILGFSTVYFIERNMIA-- 112
+L E GLI M +GL N + + A + + + + F F+LG +F+ ++
Sbjct: 72 LLSEIGLIFYMFLVGLELNPQYLRQKLKVAILTSNVSIFFPFVLGIVLSFFVLYSLNQPN 131
Query: 113 -------ALFVGITLGNTAIEVTSGVLVRERVKKE-ISSVLMGAAFADDIIAVYLIGLLT 164
ALF+G + TA V + +L + K + ++ + A DDI A L+ +
Sbjct: 132 KTSFIPFALFIGAAMSITAFPVLARILKDTGLDKTPLGTLGLTCASVDDISAWCLLAIAI 191
Query: 165 GITQGS--FSLYPMVVLTIKIVVFIVATLLISEFVFKRSARFYNVVKDLHV-FFTFTIIL 221
+T+ F +P + + I+V+ V + + FK R Y L TF I+
Sbjct: 192 AVTRTDNIFGAFPTL---LGIIVYTVFMVTLGRKFFKYILRNYGQKNYLSQGLLTFIYIM 248
Query: 222 TFMLAFLAEDIGLNQIIGAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIP 281
+ A L E IG++ I G ++ G + + EL ++ E + F +P
Sbjct: 249 VILSAMLTEWIGIDVIFGGFILGAILPKNTNLS----------TELATKTEDFVSTFLLP 298
Query: 282 LFFIY------VGLMFQPNVREISVLMIALLYLAAILGKLIGCGLGMLLFGSSLRDAIIV 335
+FF Y +GL+ +P + + L++A AAI GK G + G ++A +
Sbjct: 299 IFFAYSGLSTDLGLLNKPYLWAVCALVVA----AAIAGKYCGVYVTTRALGVEKQEAKAL 354
Query: 336 GVGMGGRGSLELAILKLGLEKGLINESLFATIVIVSMLTALST 378
G M RG EL IL +GL+ G+I+ +F VI++++T + T
Sbjct: 355 GWLMNTRGLTELIILNVGLKLGVISPVIFTMFVIMAIITTIIT 397
>pir||T05602 hypothetical protein F9D16.170 - Arabidopsis thaliana
>gi|4454039|emb|CAA23036.1| (AL035394) putative
Na+/H+-exchanging protein [Arabidopsis thaliana]
>gi|7269218|emb|CAB79325.1| (AL161559) putative
Na+/H+-exchanging protein [Arabidopsis thaliana]
Length = 820
Score = 120 bits (298), Expect = 3e-26
Identities = 107/407 (26%), Positives = 200/407 (48%), Gaps = 48/407 (11%)
Query: 4 IFDLSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLA-------IVKPSEELKVL 56
I + I+L++ + L +LL+ +IA I+ GI+LGP L V P + L VL
Sbjct: 34 ILQICIVLLLTRLLAFLLRPLRQPRVIAEIVGGILLGPSALGKSTKFINTVFPPKSLTVL 93
Query: 57 ---GEFGLIMMMLYMGLTSNFSAISRNKVKATIVATLGVAFSFILGFSTVYFIERNMIA- 112
GLI + +GL + ++ R +A +A G+ F+LG T + + R+ IA
Sbjct: 94 DTLANLGLIFFLFLVGLELDPKSLKRTGKRALSIALAGITLPFVLGIGTSFAL-RSSIAD 152
Query: 113 -------ALFVGITLGNTAIEVTSGVLVRERV-KKEISSVLMGAAFADDIIAVYLIGLLT 164
+F+G+ L TA V + +L ++ +I + + AA +D+ A L+ L
Sbjct: 153 GASKAPFLVFMGVALSITAFPVLARILAEIKLLTTDIGKIALSAAAVNDVAAWILLALAV 212
Query: 165 GIT-QGSFSLYPMVVLT-----IKIVVFIVATLLISEFVFKRSARFYNVVKDLHVFFTFT 218
++ +GS L + V + +F+V + + + KR V +L+V T
Sbjct: 213 ALSGEGSSPLTSLWVFLSGCGFVLFCIFVVQPGI--KLIAKRCPEG-EPVNELYVCCTLG 269
Query: 219 IILTFMLAFLAEDIGLNQIIGAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEF 278
I+L +F+ + IG++ + GA++ G+ + N L+ ++E ++
Sbjct: 270 IVLA--ASFVTDFIGIHALFGAFVIGVIFPKEGNFA----------NALVEKVEDLVSGL 317
Query: 279 FIPLFFIYVGLMFQPNVREI----SVLMIALLYLAAILGKLIGCGLGMLLFGSSLRDAII 334
F+PL+F+ GL + NV I S ++ L+ A GK+IG L L L ++
Sbjct: 318 FLPLYFVSSGL--KTNVATIQGAQSWGLLVLVIFNACFGKIIGTVLVSLYCKVPLDQSLA 375
Query: 335 VGVGMGGRGSLELAILKLGLEKGLINESLFATIVIVSMLTA-LSTPI 380
+G M +G +EL +L +G ++G++N+ +FA +V++++ T ++TP+
Sbjct: 376 LGFLMNTKGLVELIVLNIGKDRGVLNDQIFAIMVLMAIFTTFMTTPL 422
>pir||T45912 hypothetical protein F5K20.20 - Arabidopsis thaliana
>gi|7629992|emb|CAB88334.1| (AL132960) putative protein
[Arabidopsis thaliana]
Length = 842
Score = 120 bits (297), Expect = 4e-26
Identities = 113/437 (25%), Positives = 204/437 (45%), Gaps = 62/437 (14%)
Query: 1 MNYIFDL-----SILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLAI-------VK 48
+N+ F L ++++ V++ L L K +IA I+ GI+LGP L +
Sbjct: 22 LNFAFPLLIVQTALIIAVSRFLAVLFKPLRQPKVIAEIVGGILLGPSALGRNMAYMDRIF 81
Query: 49 PSEELKVL---GEFGLIMMMLYMGLTSNFSAISRNKVKATIVATLGVAFSFILGFSTVYF 105
P + +L GL+ + +GL + S+I R+ +A +A G+ FI G +
Sbjct: 82 PKWSMPILESVASIGLLFFLFLVGLELDLSSIRRSGKRAFGIAVAGITLPFIAGVGVAFV 141
Query: 106 IERNMIAA----------LFVGITLGNTAIEVTSGVLVRERV-KKEISSVLMGAAFADDI 154
I + A +F+G+ L TA V + +L ++ +I M AA +D+
Sbjct: 142 IRNTLYTAADKPGYAEFLVFMGVALSITAFPVLARILAELKLLTTQIGETAMAAAAFNDV 201
Query: 155 IAVYLIGLLTGITQ-----GSFSLYPMVVLTIKI--VVFIVATLLI----SEFVFKRSAR 203
A L+ L + G P+V L + + F+V L++ ++V KR +
Sbjct: 202 AAWILLALAVALAGNGGEGGGEKKSPLVSLWVLLSGAGFVVFMLVVIRPGMKWVAKRGSP 261
Query: 204 FYNVVKDLHVFFTFTIILTFMLAFLAEDIGLNQIIGAYLAGLTISRLRERKDPMVITRIK 263
+VV++ +V T ++ + F + IG++ I GA++ GLTI + E
Sbjct: 262 ENDVVRESYVCLTLAGVM--VSGFATDLIGIHSIFGAFVFGLTIPKDGEFGQ-------- 311
Query: 264 LNELISELEVVLLEFFIPLFFIYVGLMFQPNVREI----SVLMIALLYLAAILGKLIGCG 319
LI +E + +PL+F GL + +V +I S M+ L+ + A GK++G
Sbjct: 312 --RLIERIEDFVSGLLLPLYFATSGL--KTDVAKIRGAESWGMLGLVVVTACAGKIVGTF 367
Query: 320 LGMLLFGSSLRDAIIVGVGMGGRGSLELAILKLGLEKGLINESLFATIVIVSMLTA-LST 378
+ ++ R+A+ +G M +G +EL +L +G EK ++N+ FA +V++++ T ++T
Sbjct: 368 VVAVMVKVPAREALTLGFLMNTKGLVELIVLNIGKEKKVLNDETFAILVLMALFTTFITT 427
Query: 379 PIFF------RGVIRKL 389
P RG RKL
Sbjct: 428 PTVMAIYKPARGTHRKL 444
>gb|AAD22684.1|AC007063_10 (AC007063) putative Na+/H+ antiporter [Arabidopsis thaliana]
Length = 821
Score = 119 bits (295), Expect = 6e-26
Identities = 96/404 (23%), Positives = 194/404 (47%), Gaps = 42/404 (10%)
Query: 3 YIFDLSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLA-------IVKPSEELKV 55
++ L++++VV + ++LK +I+ IL GI+LGP L + P + V
Sbjct: 40 FVLQLTLVVVVTRFFVFILKPFRQPRVISEILGGIVLGPSVLGRSTKFAHTIFPQRSVMV 99
Query: 56 L---GEFGLIMMMLYMGLTSNFSAISRNKVKATIVATLGVAFSFILGFSTVYFIERNM-- 110
L GL+ + +G+ + + + +A +A G+ F++G + + + R+
Sbjct: 100 LETMANVGLLYFLFLVGVEMDIMVVRKTGKRALTIAIGGMVLPFLIGAAFSFSMHRSEDH 159
Query: 111 ----IAALFVGITLGNTAIEVTSGVLVR-ERVKKEISSVLMGAAFADDIIAVYLIGLLTG 165
LF+G+ L TA V + +L + + EI + M AA +D+ A L+ L
Sbjct: 160 LGQGTYILFLGVALSVTAFPVLARILAELKLINTEIGRISMSAALVNDMFAWILLALAIA 219
Query: 166 ITQGSFSLYPMVVLTIKIVVFIVATLLISE----FVFKRSARFYNVVKDLHVFFTFTIIL 221
+ + + + + + I VFI + + ++ +++ N + H+ T ++
Sbjct: 220 LAESDKTSFASLWVMISSAVFIAVCVFVVRPGIAWIIRKTPEGEN-FSEFHICLILTGVM 278
Query: 222 TFMLAFLAEDIGLNQIIGAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIP 281
+ F+ + IG + + GA++ GL I P+ +T LI +LE + +P
Sbjct: 279 --ISGFITDAIGTHSVFGAFVFGLVIP-----NGPLGLT------LIEKLEDFVSGLLLP 325
Query: 282 LFFIYVGLMFQPNVREI----SVLMIALLYLAAILGKLIGCGLGMLLFGSSLRDAIIVGV 337
LFF GL + N+ I + L + L+ A GK+IG + G +R+ I +G+
Sbjct: 326 LFFAISGL--KTNIAAIQGPATWLTLFLVIFLACAGKVIGTVIVAFFHGMPVREGITLGL 383
Query: 338 GMGGRGSLELAILKLGLEKGLINESLFATIVIVSM-LTALSTPI 380
+ +G +E+ +L +G ++ ++++ FAT+V+V++ +T + TPI
Sbjct: 384 LLNTKGLVEMIVLNVGKDQKVLDDETFATMVLVALVMTGVITPI 427
>dbj|BAB06563.1| (AP001516) Na+/H+ antiporter [Bacillus halodurans]
Length = 686
Score = 113 bits (280), Expect = 4e-24
Identities = 94/396 (23%), Positives = 186/396 (46%), Gaps = 35/396 (8%)
Query: 8 SILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFGLIMMMLY 67
+I +VV L+ + + II IL G+++GP G A++ + +LG GL+ ++
Sbjct: 14 AIAMVVFFVAPLLMSRLRIPGIIGLILAGVVIGPNGFALLDRDPTIVLLGTVGLLYIIFI 73
Query: 68 MGLTSNFSAISRNKVKATIVATL--------GVAFSFILGFSTVYFIERNMIAALFVGIT 119
GL + + + ++ + TL G+ F+FILGFST AA+ +
Sbjct: 74 AGLEIDLEGFKKYRNRSVLFGTLSFTIPFLFGLVFTFILGFSTP--------AAILLASI 125
Query: 120 LGNTAIEVTSGVLVRERVKKEIS-SVLMGAAFADDIIAVYLIGLLTGITQGSFSLYPMVV 178
LG+ + + + R + K+ + +G D +A+ ++ ++ G QG +
Sbjct: 126 LGSHTL-LAYPIASRLGISKDRGVTTAVGGTIMTDTLALLVLAIVAGSMQGELNSTFWFT 184
Query: 179 LTIKIVVFIVATLLISEFVFKRSARFYNVVKDLHVFFTFTIILTFMLAFLAEDIGLNQII 238
+ + +V+++ TL++ + K + F + + + F F + + F+ A+ A GL II
Sbjct: 185 IAVSLVLYVAITLILIPILAK--SFFRTMSSEGALEFIFVMSILFVTAYGATLAGLEPII 242
Query: 239 GAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGLMFQPNV--- 295
GA+LAGL ++R P L++ ++ V FIP F + VG++ V
Sbjct: 243 GAFLAGLALNRFILEHSP----------LMNRIKFVGNALFIPFFLLSVGMLMDIRVLLG 292
Query: 296 REISVLMIALLYLAAILGKLIGCGLGMLLFGSSLRDAIIVGVGMG-GRGSLELAILKLGL 354
+ L+ AL+ + LGK + + L+ S+ D I + G+ + + LA +G
Sbjct: 293 DPSAWLLAALVVIFVQLGKFLAAFISGKLYNYSM-DQIKLMFGLSVPQAAATLAATLVGF 351
Query: 355 EKGLINESLFATIVIVSMLTALSTPIFFRGVIRKLS 390
+ GL + ++ ++++ ++T + P RKL+
Sbjct: 352 DLGLFDSAVVNAVIVMILVTCMVGPYVVEKYARKLA 387
>pir||F70155 Na+/H+ antiporter (napA) homolog - Lyme disease spirochete
>gi|2688368|gb|AAC66821.1| (AE001150) Na+/H+ antiporter
(napA) [Borrelia burgdorferi]
Length = 701
Score = 107 bits (264), Expect = 3e-22
Identities = 90/406 (22%), Positives = 194/406 (47%), Gaps = 42/406 (10%)
Query: 3 YIFDLSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGP-----------FGLAIVKP-- 49
++ L+I+++ + S+ L+ K G+ +I I GIIL P F L I +
Sbjct: 34 FVMSLAIIVISSISIGNLVAKIGIPKVIGQITAGIILSPNAFGKIQIPLLFPLGITQIGE 93
Query: 50 ----SEELKVLGEFGLIMMMLYMGLTSNFSAISRNKVKATIVA---TLGVAFSFILGFST 102
+E++ + I+++ GL ++ + + I+ +G SF+L S
Sbjct: 94 NYLINEKIFAISTIASIILLFTAGLETDLKLFIKFLPRGGIIGITEVVGTFTSFVLMASI 153
Query: 103 VYFIERNMIAALFVGITLGNTAIEVTSGVL-VRERVKKEISSVLMGAAFADDIIAVYLIG 161
++ + +LF+GI T+ + + +L ++++ ++ + DD++++ ++
Sbjct: 154 IFNVPLISPTSLFIGIIGTPTSAGIAASILSAKKKMSTSEGVTIISTSIIDDVLSMLMLT 213
Query: 162 LLTGITQGSFSL---YPMVVLTIKIVVFIVATLLISEFVFKRSARFYNVVKDLHVFFTFT 218
+ I++ L + + IV+++ T + ++ + +R + + + T
Sbjct: 214 SVITISRSISDLDIASSIKAIVQNIVIWLCLTFSLI-YISETLSRLLKKLNSVTLATVIT 272
Query: 219 IILTFMLAFLAEDIGLNQIIGAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEF 278
+ L +A + +++G++ ++GAY+ GL +S+ D + + + KL + F
Sbjct: 273 LSLALTIASIFQNLGMSFVVGAYVFGLAMSKT----DIVYVIQDKLT--------IFERF 320
Query: 279 FIPLFFIYVGLMFQPNV---REISVLMIALLYLAAILGKLIGCGLGMLLFGSSLRDAIIV 335
FIP+FF +GLM N +E+ +L +A+ +A I+ K I C + L G + A+ +
Sbjct: 321 FIPIFFTSIGLMSDINEILSKEVLILGLAISAIA-IITKSIFCFIPALFLGFNKLGALKI 379
Query: 336 GVGMGGRGSLELAILKLGLEKGLINESLFATIVIVSML-TALSTPI 380
GM RG + L + + L G I++ +F I+I+ L T ++TPI
Sbjct: 380 ATGMVPRGEVSLIMANVALSSGFISQKIFGIIIIMVFLPTIIATPI 425
>gb|AAF24561.1|AC007764_3 (AC007764) F22C12.7 [Arabidopsis thaliana]
Length = 868
Score = 107 bits (264), Expect = 3e-22
Identities = 90/372 (24%), Positives = 181/372 (48%), Gaps = 41/372 (11%)
Query: 36 GIILGPFGLAIVK-------PSEELKVL---GEFGLIMMMLYMGLTSNFSAISRNKVKAT 85
GI+LGP L + P+ L VL GL++ + +GL + +++ R KA
Sbjct: 132 GILLGPSALGRITSYKNSIFPARSLTVLDTLANLGLLLFLFLVGLEIDLTSLRRTGKKAI 191
Query: 86 IVATLGVAFSFILGFSTVYFIERNMIAA---------LFVGITLGNTAIEVTSGVLVRER 136
+A G+ F +G T + + +F+G+ L TA V + +L +
Sbjct: 192 SIAAAGMLLPFGMGIVTSFAFPEASSSGDNSKVLPFIIFMGVALSITAFGVLARILAELK 251
Query: 137 V-KKEISSVLMGAAFADDIIAVYLIGLLTGITQGSFS-LYPMVVLTIKIVVFIVATLLIS 194
+ ++ + M AA +D+ A L+ L ++ S L P+ VL + + F++A LI
Sbjct: 252 LLTTDLGRISMNAAAINDVAAWVLLALAVSLSGDRNSPLVPLWVL-LSGIAFVIACFLIV 310
Query: 195 EFVFKRSARFYNVVKDLHVFFTFTIILTFMLAFLAED-IGLNQIIGAYLAGLTISRLRER 253
+FK +R + + + + +LA A D IG++ I GA++ G+ +
Sbjct: 311 PRIFKFISRRCPEGEPIGEMYVCVALCAVLLAGFATDAIGIHAIFGAFVMGVLFPKGHFS 370
Query: 254 KDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGLMFQPNVREISVLM----IALLYLA 309
+ ++ ++E +++ +PL+F+ GL + ++ I + +AL+ +
Sbjct: 371 -----------DAIVEKIEDLVMGLLLPLYFVMSGL--KTDITTIQGVKSWGRLALVIVT 417
Query: 310 AILGKLIGCGLGMLLFGSSLRDAIIVGVGMGGRGSLELAILKLGLEKGLINESLFATIVI 369
A GK++G LL LR+++++GV M +G +EL +L +G ++ ++++ FA +V+
Sbjct: 418 ACFGKIVGTVSVALLCKVRLRESVVLGVLMNTKGLVELIVLNIGKDRKVLSDQTFAIMVL 477
Query: 370 VSMLTA-LSTPI 380
+++ T ++TPI
Sbjct: 478 MAIFTTFITTPI 489
>pir||B71038 probable Na+/H+-exchanging protein - Pyrococcus horikoshii
>gi|3258023|dbj|BAA30706.1| (AP000006) 425aa long
hypothetical Na(+)/H(+) antiporter [Pyrococcus
horikoshii]
Length = 425
Score = 104 bits (258), Expect = 1e-21
Identities = 96/409 (23%), Positives = 189/409 (45%), Gaps = 53/409 (12%)
Query: 4 IFDLSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGP---FGLA-------IVKPSEEL 53
+F + +++AK + ++++ + ++ +L G+ LG FGL + SE +
Sbjct: 7 LFTIGTAIIIAKIGDSIVERFELPGVLGELLMGMALGNLVYFGLIKSEYLPITMGSSEVI 66
Query: 54 KVLGEFGLIMMMLYMGLTSNFSAISRNKVKATIVATLGVAFSFILGFSTVYFIERNMIAA 113
L + G+I+++ L ++ + R V A + +GV LG+ + + A
Sbjct: 67 DFLAKLGIILLLFLGALDTDIEKLKRTGVTAVVSTIMGVFVPLALGYYALRVMGYGYREA 126
Query: 114 LFVGITLGNTAIEVTSGVLV-RERVKKEISSVLMGAAFADDIIAVYLIGLLTGITQGSFS 172
G+ L T+I +T +++ ++ E+ + + A+ DD + + LI + + GS
Sbjct: 127 FAGGVLLTATSIGLTVRIMMDLGALRSEVGAASLSASVIDDFLGIALI--IFAVGSGS-- 182
Query: 173 LYPMVVLTIKIVVFIVATLLISEFVFKRSARFYNVVKDLHV---FFTFTIILTFMLAFLA 229
++ L+ KI+VF + T ++ ++ +F + LHV I L F+ A LA
Sbjct: 183 ---LLELSAKIIVFFIITGVLGWYLVDHYIKF---AEKLHVEKGVLGLVIGLMFIFAALA 236
Query: 230 EDIGLNQIIGAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGL 289
ED I G+++AGL +S+L E K ++ E+ + F IPLFF++ G
Sbjct: 237 EDWFAAAIEGSFMAGLILSKLPEGK-----------RIMEEVRSIGYGFLIPLFFVHTGA 285
Query: 290 MFQPNV-REISVLMIA-LLYLAAILGKLIGCGL-----------GMLLFGSSLRDAIIVG 336
M V + I +A +L A++GK+IG G G L + R ++ +G
Sbjct: 286 MLNLTVFKNIEAFKLAFVLTTIAVVGKVIGRGFGAWLTAWGRGRGFLFTKQNFRMSLQMG 345
Query: 337 VGMGGRGSLELAILKLGLEKGLINES-----LFATIVIVSMLTALSTPI 380
+G R + L L + + G I+ + AT++ +++ ++ P+
Sbjct: 346 IGSIPRTEVALVDLMVAIHGGAISSGNVPKFIAATLIFITVSVLITPPL 394
>emb|CAB45049.1| (AL078635) putative integral membrane ion antiporter [Amycolatopsis
orientalis]
Length = 409
Score = 104 bits (258), Expect = 1e-21
Identities = 99/398 (24%), Positives = 188/398 (46%), Gaps = 40/398 (10%)
Query: 4 IFDLSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGP--FG---LAIVKPSEE---LKV 55
+ DL++++V+A+ L + ++ P+I +L GI+LGP FG A + P++ L
Sbjct: 10 LLDLAVIVVLARLLGAVARRLDQPPVIGELLAGILLGPTLFGEGFAAALFPTDVRPFLAA 69
Query: 56 LGEFGLIMMMLYMGLTSNFSAISRNKVKATIVATLGVAFSFILGFSTVYF------IERN 109
L G+ M M +GL + + A V+ + F LG ++ +E
Sbjct: 70 LANVGVAMFMFMVGLELEQTLLRGRGKLALTVSVSSIVLPFTLGVGLAFYLAMNRPVEHR 129
Query: 110 MIAALFVGITLGNTAIEVTSGVLV-RERVKKEISSVLMGAAFADDIIAVYLIGLLTGITQ 168
+ LF+G + TA V + +L R ++ + + + A D++A L+ ++ ++
Sbjct: 130 LGFLLFIGAAMSVTAFPVLARILQDRGMLRTMLGGLALTCAAIGDVLAWCLLAVVVIVSG 189
Query: 169 GSFSLYPMVVLT----IKIVVFIVATLLISEFVFKRSARFYNVVKDLHVFFTFTIILTFM 224
G+ +++ + +++++V LL F + V+ + T
Sbjct: 190 GASGTEQWLIVLGPIYVALMLWVVRPLLRKLFTAGVTGALPTVLAGALISGAVT------ 243
Query: 225 LAFLAEDIGLNQIIGAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFF 284
E IGL+ I GA+L G+ + R E D + R ++ + + E LL +P+FF
Sbjct: 244 -----ELIGLHFIFGAFLFGVIVPR--EGTDTL---RHRIIDRVEEFNSALL---LPVFF 290
Query: 285 IYVGLMFQPNVREISVLM-IALLYLAAILGKLIGCGLGMLLFGSSLRDAIIVGVGMGGRG 343
I GL + + L+ L+ L AI GK G +G L G R + + M RG
Sbjct: 291 IVSGLKVNLSTLSATGLVEFGLVLLVAIAGKFGGAFVGARLHGLPARKSAALATLMNTRG 350
Query: 344 SLELAILKLGLEKGLINESLFATIVIVSML-TALSTPI 380
EL IL +GL+ G++++SL++ +V ++++ TA++ P+
Sbjct: 351 LTELIILTVGLQLGVLDQSLYSIMVAMAVITTAMAGPL 388
>pir||S76532 hypothetical protein - Synechocystis sp. (strain PCC 6803)
>gi|1001647|dbj|BAA10378.1| (D64002) Na(+)/H(+)
antiporter [Synechocystis sp.]
Length = 698
Score = 103 bits (255), Expect = 3e-21
Identities = 93/398 (23%), Positives = 182/398 (45%), Gaps = 40/398 (10%)
Query: 2 NYIFDLSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLAIV-KPSEELKVLGEFG 60
N + D +ILL+V L + ++ + ++ + GI+LG GL ++ + SE +K+ + G
Sbjct: 11 NPLIDFTILLLVTLILPPIFERLKLPGLVGLLFAGIVLGKSGLGVLNEDSESIKLFTDIG 70
Query: 61 LIMMMLYMGLTSNFSAISRNKVKATIVATL--------GVAFSFILGFSTVYFIERNMIA 112
I +M GL + R + ++ + +L G+A G+S F ++
Sbjct: 71 KIYLMFVAGLEIDMVDFRRTRNRSLLYGSLTFAVPLLTGLAVGLTFGYS---FNASVLLG 127
Query: 113 ALFVGITLGNTAIEVTSGVLVRERVKKEISSVLMGAAFADDIIAVYLIGLLTGITQGSFS 172
+LF TL I G+ V+ + V +GA DI A+ ++ + I GSFS
Sbjct: 128 SLFASHTLLGYPIVQRLGI-----VRNQAVMVTIGATIFTDIAALLVLAICISIHSGSFS 182
Query: 173 LYPMVVLTIKIVVFIVATLLISEFVFKRSARFYNVVKDLHVFFTFTIILTFMLAFLAEDI 232
+VV + I V+ + L++ F + F + F F ++ F+ + +E I
Sbjct: 183 PAGLVVQLVAIAVY--SALVLIGFDWAGREYFRRTGDEQSNQFLFVLLAVFLASVGSELI 240
Query: 233 GLNQIIGAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGLMFQ 292
+++I+GA+LAGL ++ V+ + E + L L FIP FFI +GL+
Sbjct: 241 NVDKIVGAFLAGLAVND--------VLGNSPVKEKVEFLGTTL---FIPFFFIGIGLLLD 289
Query: 293 PNVREISVLMIALLYLAAILGKLIGCGLGMLLFGSSLRDAIIVGVGMGGRGSLELAILKL 352
+++ + L +A ++G ++ G+ +L L + G+ M ++A
Sbjct: 290 LPAFLVTLTTLFPLVVAIVVGLILSKGVAAILAQWKLGYTWVEGLTMWSLSIPQVAATLA 349
Query: 353 GLEKG----------LINESLFATIVIVSMLTALSTPI 380
G L++E++ TI+++ ++T++ P+
Sbjct: 350 AAVAGYQAVNAAGDRLVSETVLNTIIVLMLITSIVGPL 387
>gb|AAF26906.1|AF210843_3 (AF210843) unknown [Sorangium cellulosum]
Length = 713
Score = 103 bits (254), Expect = 4e-21
Identities = 79/393 (20%), Positives = 179/393 (45%), Gaps = 34/393 (8%)
Query: 7 LSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGE-------- 58
L+++LV A++ L ++ ++ + G++LGP + + P + E
Sbjct: 16 LALILVTARASGELARRLRQPEVLGELFGGVVLGPSVVGALAPGFHRALFQEPAVGVVLS 75
Query: 59 ----FGLIMMMLYMGLTSNFSAISRNKVKATIVATLGVAFSFILGFS-TVYFIERNMIAA 113
G ++++L G+ + + + + A +A G + + ++R + +
Sbjct: 76 GISWIGALLLLLMAGIEVDVGILRKEARPGALSALGAIAPPLAAGAAFSALVLDRPLPSG 135
Query: 114 LFVGITLGNTAIEVTSGVLV-RERVKKEISSVLMGAAFADDIIAVYLIGLLTGITQGSFS 172
LF+GI L TA+ V + VL+ RE +++ + V + A ++ A L+ + T S+
Sbjct: 136 LFLGIVLSVTAVSVIAKVLIERESMRRSYAQVTLAAGVVSEVAAWVLVAM----TSSSYG 191
Query: 173 LYPMVVLTIKIVV---FIVATLLISEFVFKRSARFY-NVVKDLHVFFTFTIILTFMLAFL 228
P + + ++ F++ +L+ + + R+ + + + ++LTF+ A L
Sbjct: 192 ASPALAVARSALLASGFLLFMVLVGRRLTHLAMRWVADATRVSKGQVSLVLVLTFLAAAL 251
Query: 229 AEDIGLNQIIGAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVG 288
+ +GL+ ++GA+ G+ ++ P L+ ++ ++ F P+FF+ G
Sbjct: 252 TQRLGLHPLLGAFALGVLLNSAPRTNRP----------LLDGVQTLVAGLFAPVFFVLAG 301
Query: 289 LMFQPNVREISVLM--IALLYLAAILGKLIGCGLGMLLFGSSLRDAIIVGVGMGGRGSLE 346
+ + +ALL A K++ LG L G +A +V VG+ +G +
Sbjct: 302 MRVDVSQLRTPAAWGTVALLLATATAAKVVPAALGARLGGLRGSEAALVAVGLNMKGGTD 361
Query: 347 LAILKLGLEKGLINESLFATIVIVSMLTALSTP 379
L + +G+E GL++ + +V+++T ++P
Sbjct: 362 LIVAIVGVELGLLSNEAYTMYAVVALVTVTASP 394
>pir||C75176 na+/h+ antiporter (napa-2) PAB0390 - Pyrococcus abyssi (strain
Orsay) >gi|5458000|emb|CAB49490.1| (AJ248284) Na+/H+
antiporter (napA-2) [Pyrococcus abyssi]
Length = 426
Score = 100 bits (246), Expect = 4e-20
Identities = 92/409 (22%), Positives = 191/409 (46%), Gaps = 53/409 (12%)
Query: 4 IFDLSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGP---FGLA-------IVKPSEEL 53
+F + + L++AK + ++++ + ++ ++ G++LG FG+ + SE +
Sbjct: 8 LFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEVI 67
Query: 54 KVLGEFGLIMMMLYMGLTSNFSAISRNKVKATIVATLGVAFSFILGFSTVYFIERNMIAA 113
L + G+I ++ L ++ + + + ATI +GV ILG+ + ++ + A
Sbjct: 68 DFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYSHREA 127
Query: 114 LFVGITLGNTAIEVTSGVLVRERV-KKEISSVLMGAAFADDIIAVYLIGLLTGITQGSFS 172
G+ L T+I +T V++ V + E+ + + A+ DD + + LI + + GS
Sbjct: 128 FAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALI--IFAVGSGS-- 183
Query: 173 LYPMVVLTIKIVVFIVATLLISEFVFKRSARFYNVVKDLHV---FFTFTIILTFMLAFLA 229
++ L++KI+ F + T ++ + + RF + LHV + + F+ A LA
Sbjct: 184 ---LLGLSMKIIAFFIITGILGWYSIDKYIRF---AERLHVEKGILGMAVGMMFLFAALA 237
Query: 230 EDIGLNQIIGAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGL 289
E I G+++ GL +S+L E K ++ E+ + IP+FFI+ G
Sbjct: 238 EGWFAAAIEGSFMMGLILSKLPEGK-----------RIMEEVRSIGYGLLIPIFFIHTGA 286
Query: 290 MFQPNV-REISVLMIAL-LYLAAILGKLIGCGLG-----------MLLFGSSLRDAIIVG 336
M V R + +AL L A++GK+ G G G L + + ++ +G
Sbjct: 287 MLNLTVFRNADAIKLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMG 346
Query: 337 VGMGGRGSLELAILKLGLEKGLIN-----ESLFATIVIVSMLTALSTPI 380
+G R + L L + + G I+ + + AT++ +++ ++ P+
Sbjct: 347 IGSIPRTEVALVDLMVAIHGGAISPDDVPKFIAATLIFITVSVLITPPL 395
>gi|6322367 Yjl094cp [Saccharomyces cerevisiae] >gi|731972|sp|P40309|YJJ4_YEAST
HYPOTHETICAL 97.1 KD PROTEIN IN BCK1-TOK1 INTERGENIC
REGION >gi|630170|pir||S46584 probable membrane protein
YJL094c - yeast (Saccharomyces cerevisiae)
>gi|521094|emb|CAA54359.1| (X77087) 12 transmembrane
domains; J0909 ORF [Saccharomyces cerevisiae]
>gi|1008268|emb|CAA89387.1| (Z49369) ORF YJL094c
[Saccharomyces cerevisiae]
Length = 873
Score = 95.6 bits (234), Expect = 9e-19
Identities = 99/416 (23%), Positives = 191/416 (45%), Gaps = 56/416 (13%)
Query: 3 YIFDLSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGP--FGLA-----IVKPSEE--- 52
++F ++L+V + +I+ +++G+ILGP FG + P+
Sbjct: 26 FLFQACLILLVCNLIHIPFSMMRQPKVISEVISGVILGPTIFGQIPNYTNTIFPTSSIPG 85
Query: 53 LKVLGEFGLIMMMLYMGLTSNFSAISRNKVKATIVATLGVAFSFILGFSTVYFI------ 106
L ++ G+I+ M ++GL + + I ++ KA ++ + +A F GF + I
Sbjct: 86 LNLVANLGIILFMFFLGLEVDIAFIKKHLKKALVIGIVTLAVPF--GFGCLLAIPLFHTY 143
Query: 107 ------ERNM---IAALFVGITLGNTAIEVTSGVLVRER-VKKEISSVLMGAAFADDIIA 156
ER++ + +F+ +++ TA V +L R +K V++ A +DI+
Sbjct: 144 ANKTEGERHIKFSVFMVFIAVSISVTAFPVLCRILNELRLIKDRAGIVVLAAGIINDIMG 203
Query: 157 VYLIGLLTGITQGSFSLYPMVVLTIKIVVFIVATLLISEFVFKRSARFYNV-------VK 209
L+ L ++ S V T+ I++ A LI F K R+ + K
Sbjct: 204 WILLALSIILSSAEGS----PVNTVYILLITFAWFLIYFFPLKYLLRWVLIRTHELDRSK 259
Query: 210 DLHVFFTFTIILTFMLAFLAEDIGLNQIIGAYLAGLTISRLRERKDPMVITRIKLNELIS 269
+ + + F+ A+ + IG++ I GA++AGL + R D V+ KL E +
Sbjct: 260 PSPLATMCILFIMFISAYFTDIIGVHPIFGAFIAGLVVPR----DDHYVV---KLTERME 312
Query: 270 ELEVVLLEFFIPLFFIYVGLMFQPNV----REISVLMIALLYLAAILGKLIGCGLGMLLF 325
++ ++ FIP++F GL + R+ + + AI K+I L L
Sbjct: 313 DIPNIV---FIPIYFAVAGLNVDLTLLNEGRDWGYVFATIGI--AIFTKIISGTLTAKLT 367
Query: 326 GSSLRDAIIVGVGMGGRGSLELAILKLGLEKGLINESLFATIVIVSML-TALSTPI 380
G R+A GV M +G +E+ +L +GL G+I+ +F V+++++ T ++TP+
Sbjct: 368 GLFWREATAAGVLMSCKGIVEIVVLTVGLNAGIISRKIFGMFVLMALVSTFVTTPL 423
>emb|CAC12310.1| (AL445066) Na+/H+ antiporter related protein [Thermoplasma
acidophilum]
Length = 381
Score = 95.6 bits (234), Expect = 9e-19
Identities = 85/377 (22%), Positives = 177/377 (46%), Gaps = 21/377 (5%)
Query: 20 LLKKRGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFGLIMMMLYMGLTSNFSAISR 79
LL + + ++A+I++GII+G L I+ PS+ + + L ++L +G+ +N I
Sbjct: 6 LLDRFRIPEVVAYIVSGIIVGAGVLRIIMPSQTISDIESISLFFIILSIGVEANTEYIYG 65
Query: 80 NKVKATIVATLGVAFSFILGFSTVYFIER-NMIAALFVGITLGNTAIEVTSGVLVR-ERV 137
N ++ + G F ILG + + FI I + V +++ +I + S +L++ + +
Sbjct: 66 NLKRSILFTISGFIFPMILGLAVLNFISPFGFIPSFVVSLSVSVPSISIISVLLMKYDLL 125
Query: 138 KKEISSVLMGAAFADDIIAVYLIGLLTG-----ITQGSFSLYPMVVLTIKIVVFIVATLL 192
K +++ + DI+A ++ T + F + VV+ I ++ +
Sbjct: 126 KVNGGRLILSSVVLTDIVAFIMLSATTENVYHVLESLGFVILFFVVIAIFDIIIRRRAIG 185
Query: 193 ISEFVFKRSARFYNVVKDLHVFFTFTIILTFMLAFLAEDIGLNQIIGAYLAGLTISRLRE 252
I ++ KR + ++ F+ II +++ + E IG+ ++G++ AG+ I E
Sbjct: 186 IMAWIEKREEK----TNMEYILFSMIIIAGLLVSIIFEVIGITYVLGSFFAGILI---HE 238
Query: 253 RKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGLMFQPNVREISVLMIALLYLAAIL 312
RI L++ L+ + FFIPLFF G+ + ++ + L + +
Sbjct: 239 ASVGEKYHRI----LVNTLKRINDSFFIPLFFSIAGISVVFPHLDTFIIFLPALIVIIVS 294
Query: 313 GKLIGCGLGMLLFGSSLRDAIIVGVGMGGRGSLELAILKLGLEKGLINESLFATIVIVSM 372
G L+ L F S+ + V +GGRG++ + I + + G+I ++ ++ ++
Sbjct: 295 GTLLNYALSK-RFIRSITPLTTMSV-LGGRGAVGVIIAAIAYDTGIITSIQYSLAILGTV 352
Query: 373 LTAL-STPIFFRGVIRK 388
L +L TP+ V R+
Sbjct: 353 LISLIITPLISLAVARR 369
>sp|P39830|YBAL_ECOLI HYPOTHETICAL 59.4 KD PROTEIN IN GSK-FSR INTERGENIC REGION
>gi|7444646|pir||E64778 probable membrane protein ybaL -
Escherichia coli >gi|1773160|gb|AAB40232.1| (U82664)
similar to Y. enterocolitica RosB [Escherichia coli]
>gi|1786685|gb|AAC73580.1| (AE000154) putative transport
protein [Escherichia coli K12]
Length = 558
Score = 95.2 bits (233), Expect = 1e-18
Identities = 85/386 (22%), Positives = 168/386 (43%), Gaps = 30/386 (7%)
Query: 11 LVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFGLIMMMLYMGL 70
LV+A L L K + P++ ++L G++ GPF V ++ L E G+I++M +GL
Sbjct: 15 LVLAFILGMLANKLRISPLVGYLLAGVLAGPFTPGFVADTKLAPELAELGVILLMFGVGL 74
Query: 71 TSNFSAISRNKVKATIVATLGVAFSFILGFSTVYFIERNMIAALFVGITLGNTAIEVTSG 130
+ + K A A +A + +LG + + +++ + G+ L + V
Sbjct: 75 HFSLKDLMAVKAIAIPGAIAQIAVATLLGMALSAVLGWSLMTGIVFGLCLSTASTVVLLR 134
Query: 131 VL-VRERVKKEISSVLMGAAFADDIIAVYLIGLLTGIT----QGSFSLYPMVV---LTI- 181
L R+ + + + +G +D++ V + LL + QG + V +TI
Sbjct: 135 ALEERQLIDSQRGQIAIGWLIVEDLVMVLTLVLLPAVAGMMEQGDVGFATLAVDMGITIG 194
Query: 182 KIVVFIVATLLISE----FVFKRSARFYNVVKDLHVFFTFTIILTFMLAFLAEDI-GLNQ 236
K++ FI +L+ ++ RSA +F + L +AF A ++ ++
Sbjct: 195 KVIAFIAIMMLVGRRLVPWIMARSA----ATGSRELFTLSVLALALGVAFGAVELFDVSF 250
Query: 237 IIGAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGLMFQPNVR 296
+GA+ AG MV+ +L+ + + L + F LFF+ VG++F P +
Sbjct: 251 ALGAFFAG------------MVLNESELSHRAAHDTLPLRDAFAVLFFVSVGMLFDPLIL 298
Query: 297 EISVLMIALLYLAAILGKLIGCGLGMLLFGSSLRDAIIVGVGMGGRGSLELAILKLGLEK 356
L + + GK + + LFG S R A+ + + G + LG+
Sbjct: 299 IQQPLAVLATLAIILFGKSLAAFFLVRLFGHSQRTALTIAASLAQIGEFAFILAGLGMAL 358
Query: 357 GLINESLFATIVIVSMLTALSTPIFF 382
L+ ++ ++ ++L+ + P+ F
Sbjct: 359 NLLPQAGQNLVLAGAILSIMLNPVLF 384
>pir||A69845 Na+/H+ antiporter homolog yjbQ - Bacillus subtilis
>gi|2633518|emb|CAB13021.1| (Z99110) similar to Na+/H+
antiporter [Bacillus subtilis]
Length = 614
Score = 95.2 bits (233), Expect = 1e-18
Identities = 101/414 (24%), Positives = 186/414 (44%), Gaps = 54/414 (13%)
Query: 4 IFDLSILLVVAKSLEWLLK--KRGVHPIIAHILTGIILGPFGLAIVKPSEE-LKVLGEFG 60
+ L ++L+VA LL K + ++A I+ G+I+G GL +V + L+ L G
Sbjct: 6 VASLVVVLIVAFLTPILLHRFKLSIPVVVAEIIMGLIIGKSGLNLVVEGDTWLQTLSMLG 65
Query: 61 LIMMMLYMGLTSNFSAISRNKVK--------------ATIVATLGVAFSFIL---GFSTV 103
I +M GL +FS+ + K K A V +G+ +L GF
Sbjct: 66 FIFLMFLSGLEIDFSSFEKGKKKQFLPNGKEAPNTFAAASVIFVGIFILSLLLSYGFVLA 125
Query: 104 YFIERNMIAALFVG-ITLGNTAIEVTSGVLVRERV-KKEISSVLMGAAFADDIIAVYLIG 161
FI+ + L + I+LG V L ER+ I +++ A D+ + L+
Sbjct: 126 GFIQNAFLMTLIISTISLG-----VVVPTLKEERIMNSNIGQIILLVAVIADLATMILLA 180
Query: 162 LLTGIT-QGSFSLYPMVVLTIKIVVFIVATLLISEFVFKRSARFYNVVKDLHVFFTFTII 220
+ + + + S +++ +++L VV + F +S + FT I+
Sbjct: 181 VFSSLYGEDSGNMWLLMILFAAGVVLYFFGRVFKHRSFVQSMSKGTIQIGTRAIFTLIIV 240
Query: 221 LTFMLAFLAEDIGLNQIIGAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFI 280
L L+E +G I+GA+LAG+ +S L K EL+ +L+ F I
Sbjct: 241 LVA----LSESLGAENILGAFLAGVLVSLLSPNK-----------ELVQQLDSFGYGFLI 285
Query: 281 PLFFIYVGL------MFQPNVREISVLMIALLYLAAILGKLIGCGLGMLLFGSSLRDAII 334
P+FF+ VG+ +FQ + ++MI LL LA ++ K+I + L R
Sbjct: 286 PIFFVMVGVKLDIWTLFQD---KTILIMIPLLLLALLVSKII--PVMYLKKWYDNRTIFA 340
Query: 335 VGVGMGGRGSLELAILKLGLEKGLINESLFATIVIVSMLTALSTPIFFRGVIRK 388
G + SL +A +G + +I+ ++ +++V+++ ++ TPI F+ + ++
Sbjct: 341 SGFLLTSTLSLVIAAATIGQQLHVISTNMSGALILVAVIASIFTPICFKKLYKR 394
>gi|11497833 Na+/H+ antiporter (napA-1) [Archaeoglobus fulgidus]
>gi|7451786|pir||A69277 Na+/H+ antiporter (napA-1)
homolog - Archaeoglobus fulgidus
>gi|2650426|gb|AAB91016.1| (AE001091) Na+/H+ antiporter
(napA-1) [Archaeoglobus fulgidus]
Length = 377
Score = 92.4 bits (226), Expect = 8e-18
Identities = 93/366 (25%), Positives = 168/366 (45%), Gaps = 30/366 (8%)
Query: 23 KRGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFGLIMMMLYMGLTSNFSAISRNKV 82
K V ++ I+ G+I G L ++ SE L L FGLI +M GL + + ++
Sbjct: 26 KLRVPVVVLEIVLGMIFGVSFLNVIYASEWLSFLSLFGLIFLMFLAGLEIDADVVLKSGH 85
Query: 83 KATIVATLGVAFSFILGFSTVYFIERNMIAALFVGITLGNTAIEVTSGVLVRERVKKE-I 141
+VA ++ + + + + M LF I L N A+ V VL ++KE
Sbjct: 86 LKRVVAFFALSLALSVALTAL------MGLNLFYAIILTNVAVGVVVSVLREIGLEKEDF 139
Query: 142 SSVLMGAAFADDIIAVYLIGL--LTGITQGSFSLYPMVVLTIKIVVFIVATLLISEFVFK 199
+ + A D ++L+ + +TG Q +F+ +++ + + + L+I F
Sbjct: 140 GQLNIVTALVSDFSTMFLLSIYFITGYLQVAFA---FLIILVFLAAYRFGKLVIWHFPDF 196
Query: 200 RSARFYNVVKDLHVFFTFTIILTFMLAFLAEDIGLNQIIGAYLAGLTISRLRERKDPMVI 259
S F + ++ V + I++ F+ L+ +G+ I+GA+LAG+ +S I
Sbjct: 197 ISRWFSDEPSEIGVRGSLAIMILFV--GLSSLLGVEAILGAFLAGVLLS----------I 244
Query: 260 TRIKLNELISELEVVLLEFFIPLFFIYVGLMFQPNVREISVLMIALLYLAAILGKLIGCG 319
T +L +L + FFIP+FFI G + I LL ++ K G
Sbjct: 245 TFRGGKKLYDKLYGMGFGFFIPIFFIKTGSELNITQAGEGIGFILLLLAVSVAVK----G 300
Query: 320 LGMLLFGSS--LRDAIIVGVGMGGRGSLELAILKLGLEKGLINESLFATIVIVSMLTALS 377
+ L+F S+ LR AI +G+ + SL +A + +G+ G+I E +V ++++ L
Sbjct: 301 IPSLIFASNFGLRRAISMGMLQSTKLSLTIAGVAIGVSSGVITEFESTALVTFTIISCLL 360
Query: 378 TPIFFR 383
+P FR
Sbjct: 361 SPTLFR 366
>pir||D71642 glutathione-regulated potassium-efflux system protein kefb (kefB)
RP810 - Rickettsia prowazekii
>gi|3861337|emb|CAA15236.1| (AJ235273)
GLUTATHIONE-REGULATED POTASSIUM-EFFLUX SYSTEM PROTEIN
KEFB (kefB) [Rickettsia prowazekii]
Length = 575
Score = 90.5 bits (221), Expect = 3e-17
Identities = 87/385 (22%), Positives = 172/385 (44%), Gaps = 24/385 (6%)
Query: 4 IFDLSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFGLIM 63
+ ++ ILL A + +LK+ + P++ +++ G +G GL IV ++ K+LGE G++
Sbjct: 6 LINVIILLGTAVFIVAILKRFRLSPVLGYLIAGAAIGDHGLKIVT-YDQTKLLGELGVVF 64
Query: 64 MMLYMGLTSNFSAISRNKVKATIVATLGVAFSFILGFSTVYFIERNMIAALFVGITLGNT 123
++ +GL +F + + + +L V + I+ + I+ N AA+ G L +
Sbjct: 65 LLFAIGLELSFERLKAMRRYVFGLGSLQVLTTAIVIAGAMVLIDGNSSAAIITGGGLALS 124
Query: 124 AIEVTSGVLVRERVKK-EISSVLMGAAFADDIIAV---YLIGLLTGITQGSFS----LYP 175
+ + V+ R + +I + + D+ V ++ LL + S + +
Sbjct: 125 STALVMQVIDENRSQSTQIGRISLAILLLQDLAVVPLLVIVPLLASNNKASLAVALGIAF 184
Query: 176 MVVLTIKIVVFIVATLLISEFVFKRSARFYNVVKDLHVFFTFTIILTFMLAFLAEDIGLN 235
+ +T + +FIV +L+ VF + N +L + T I+L+ A+ E GL+
Sbjct: 185 LKAVTALLTIFIVGRVLLRP-VFSFISSESNNTSELPISMTLLIVLS--AAWATETFGLS 241
Query: 236 QIIGAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGLMFQPNV 295
+GA++AG+ ++ R++ E I + F+ LFF+ VG+
Sbjct: 242 LALGAFVAGVLVAETE--------FRLQAEESIYPFK----SLFLGLFFMTVGMNIDALE 289
Query: 296 REISVLMIALLYLAAILGKLIGCGLGMLLFGSSLRDAIIVGVGMGGRGSLELAILKLGLE 355
+ I L +A I K + +LFG + A G+ + G + LG +
Sbjct: 290 MYEKISHILTLSIALICIKTLIITAFCILFGFNKGVAFYSGLLLSQGGEFGFILFSLGKD 349
Query: 356 KGLINESLFATIVIVSMLTALSTPI 380
G++ ES +++V T TP+
Sbjct: 350 SGVLEESTADILLLVVTFTMALTPL 374
>pir||C70474 Na+/H+-exchanging protein - Aquifex aeolicus
>gi|2984253|gb|AAC07780.1| (AE000768) Na(+)/H(+)
antiporter [Aquifex aeolicus]
Length = 422
Score = 88.9 bits (217), Expect = 9e-17
Identities = 83/370 (22%), Positives = 170/370 (45%), Gaps = 29/370 (7%)
Query: 19 WLLKKRGVHPIIAHILTGIILGPFGLAIVKPSEELK---VLGEFGLIMMMLYMGLTSNFS 75
+ +K + IIA ++ G + P + P E++K + G+I++ ++GL +F
Sbjct: 26 YTFQKVNIPSIIAFMIIGFLAQP-----LVPPEKIKDFEIFKHAGIILLFFFIGLEYSFE 80
Query: 76 AISRNKVKATIVATLGVAFSFILGFSTVYFIERNMIAALFVGITLGNTAIEVTSGVLVR- 134
+ R + A ++ F+FI F Y ++I AL + ++ + + +L+
Sbjct: 81 RL-RTMLGAWKTGSIDFVFNFIPPFIIAYAFGFDLITALILAAVFYPSSTSIIAKLLMDY 139
Query: 135 ERVKKEISSVLMGAAFADDIIAVYLIGLLTGITQ-GSFSLYPMVVLTIKIVVFIVATLLI 193
+R+ + +L+G +D++A+ L+ ++ + + GS + V +K+ V + LI
Sbjct: 140 KRIASPEAELLIGILIFEDLVAILLLTIIIPLKEAGSIEFTTIPVSLVKLGVAFLLFWLI 199
Query: 194 SEFVFKRSARFYNVVKDLHVFFTFTIILTFMLAFLAEDIGLNQIIGAYLAGLTISRLRER 253
+++ + + + V + +F FT+ L + + +G+++ +GA+L G
Sbjct: 200 YKYLIPKINAWLDRVSEEDIFIFFTLGLVLSIGTIFHSLGISEALGAFLLG--------- 250
Query: 254 KDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGLMFQPNVREISVLMIALLYLAAILG 313
+++ K+ E I + L E + LFF + Q E L+I L+ L IL
Sbjct: 251 ---VIVPETKVLENIEKQLSDLKELSMGLFFFFFAYETQLTKPENLGLLILLIVLGIIL- 306
Query: 314 KLIGCGLGMLLFGSSLRDAIIVGVGMGGRGSLELAILKLGLEKGLINES---LFATIVIV 370
K+I L +FG + + + RG E +++ E L + S +F T VI
Sbjct: 307 KIISTYLAGYVFGLKKKSRLRASLSFVPRG--EFSVIMTSFEPALKSTSIPFIFLTAVIG 364
Query: 371 SMLTALSTPI 380
S+L AL+ +
Sbjct: 365 SILFALAPKV 374
>gb|AAF69026.1| (AF182516) unknown [Pseudomonas putida]
Length = 390
Score = 87.8 bits (214), Expect = 2e-16
Identities = 91/394 (23%), Positives = 183/394 (46%), Gaps = 30/394 (7%)
Query: 4 IFDLSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFGLIM 63
+F L+++L+V L ++ + + ++L GI++GP ++ + + L E G++M
Sbjct: 5 VFLLAVVLLVP-----LAQRLKMGAVPGYLLAGILIGPSVFGLLGNPDNVARLSEMGVVM 59
Query: 64 MMLYMGLTSNFSAISRNKVKATIVATLGVAFSFIL-GFSTVYFIERNMIAALFVGITLGN 122
++ +GL + + + V +L V + +L G + +++ AA+ +G+ L
Sbjct: 60 LLFVIGLELSPKRLWTMRRALFGVGSLQVGLTAVLLGLLAFWLFDQSKPAAIVLGLGLAL 119
Query: 123 TAIEVTSGVLV-RERVKKEISSVLMGAAFADDIIAVYLIG---LLTG-ITQGSFSLYPMV 177
++ VL R+ + K + + DI A+ LI LL G ++ +P++
Sbjct: 120 SSTAFGLQVLAERKDLGKPHGRMAVAILLFQDIAAIPLIAVVPLLGGDVSTADEGAWPLL 179
Query: 178 VLTIKIVVFIVATLLISEFVFKRSARFYNVVKDLHVFFTFTIILTFM-LAFLAEDIGLNQ 236
+ + I V IV + +FK + V L T T +L + A+L E +G++
Sbjct: 180 AVVVGIGVLIVFGRYLLTPIFK-----WTVGSGLPELSTATALLVVLGTAWLMEHVGVSM 234
Query: 237 IIGAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGLMFQPNVR 296
+GA+LAG+ ++ R +EL +++E + F+ LFF+ VG+ +
Sbjct: 235 ALGAFLAGVLMAESPFR-----------HELETQIEPIK-GLFLGLFFVGVGMSADLRLL 282
Query: 297 EISVLMIALLYLAAILGKL-IGCGLGMLLFGSSLRDAIIVGVGMGGRGSLELAILKLGLE 355
LM+ L L + KL + GLG + G + A+ +GV + G + KL LE
Sbjct: 283 FGMPLMVLGLTLLLVAIKLPLLYGLGRTMGGLNKSQALCLGVVLASGGEFXFVVFKLALE 342
Query: 356 KGLINESLFATIVIVSMLTALSTPIFFRGVIRKL 389
++ +++ +V+ L+ P+ + R+L
Sbjct: 343 HQVLTQAVHDLLVLAITLSMAVVPLVMMALARQL 376
>gb|AAD10158.1| (AC005917) putative potassium/proton antiporter [Arabidopsis
thaliana]
Length = 574
Score = 87.4 bits (213), Expect = 3e-16
Identities = 84/393 (21%), Positives = 177/393 (44%), Gaps = 29/393 (7%)
Query: 1 MNYIFDLSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFG 60
+ I DL +++V A G I ++L G I+GP GL+ V +++ + +FG
Sbjct: 152 LRLISDLVVVIVSATCGGIAFACAGQPVITGYLLAGSIIGPGGLSFVSEMVQVETVAQFG 211
Query: 61 LIMMMLYMGLTSNFSAISRNKVKATIV--ATLGVAFSFILGFSTVYFIERNMIAALFVGI 118
+I ++ +GL FSA V+A + L + L T + +FVG
Sbjct: 212 VIFLLFALGL--EFSAAKLRVVRAVAIPGGLLQIFLFMCLSGITASLCGGKLTEGIFVGA 269
Query: 119 TLGNTAIEVTSGVLVRER----VKKEISSVLMGAAFADDIIAVYLIGLLTGITQGSFSLY 174
L ++ V L+ + +I+ +G FA + ++G +G+ QG S+
Sbjct: 270 FLSMSSTAVVLKFLMERNSISALHGQITDCAVGLLFA----LLPVLGGTSGVLQGVLSMA 325
Query: 175 PMVVLTIKIV--VFIVATLLISEFVFKRSARFYNVVKDLHVFFTFTIILTFMLAFLAEDI 232
+ + I + +F+++ + F+ K + +L+ L ++A+ ++ +
Sbjct: 326 KSLAILIAFLGALFVLSRTWVPWFL-KLMTSLSSQTNELYQLAAVAFCL--LVAWCSDKL 382
Query: 233 GLNQIIGAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGLMFQ 292
GL+ +G++ AG+ IS + + L + S++E + FF LF +G++
Sbjct: 383 GLSLELGSFAAGVMISTTD-------LAQHTLEQARSQVEPIR-NFFAALFLASIGMLIH 434
Query: 293 PNV--REISVLMIALLYLAAILGKLIGCGLGMLLFGSSLRDAIIVGVGMGGRGSLELAIL 350
+ + +L+ A+L + I K + + + +FG + + A++VG+ + G +L
Sbjct: 435 MHFLWNHVDILLAAVLLVIVI--KTVVVAIVVKVFGYNNKTAVLVGMSLAQIGEFAFVLL 492
Query: 351 KLGLEKGLINESLFATIVIVSMLTALSTPIFFR 383
LI L+ ++ + L+ ++TP+ F+
Sbjct: 493 SRASNLHLIESKLYLLLLGTTALSLVTTPLLFK 525
>pir||E82956 probable potassium efflux transporter PA5518 [imported] -
Pseudomonas aeruginosa (strain PAO1)
>gi|9951855|gb|AAG08903.1|AE004964_6 (AE004964) probable
potassium efflux transporter [Pseudomonas aeruginosa]
Length = 567
Score = 87.4 bits (213), Expect = 3e-16
Identities = 80/384 (20%), Positives = 163/384 (41%), Gaps = 33/384 (8%)
Query: 20 LLKKRGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFGLIMMMLYMGLTSNFSAISR 79
L + + P++ ++L G++ GPF V + + E G+I++M +GL + +
Sbjct: 23 LANRLRISPLVGYLLAGVLAGPFTPGYVADQALSQEIAELGVILLMFGVGLHFSLKDLLS 82
Query: 80 NKVKATIVATLGVAFSFILGFSTVYFIERNMIAALFVGITLGNTAIEVTSGVLV-RERVK 138
K A A + + + +LG + + L G++L + V L R+ +
Sbjct: 83 VKAIAIPGALVQIGVATLLGIGLAKLLGWSFGGGLVFGLSLSVASTVVLLRALEQRQLLD 142
Query: 139 KEISSVLMGAAFADDIIAVY-------LIGLLTGITQGSFS--LYPMVVLTIKIVVFIVA 189
+ + +G +D+ V L G L G T G + L+P+++ K+ F+
Sbjct: 143 TKRGRIAIGWLIVEDLAMVLTLVLLPALAGTLGGKTDGGDAGLLWPLLITLGKVAAFVAL 202
Query: 190 TLL----ISEFVFKRSARFYNVVKDLHVFFTFTII-LTFMLAF-LAEDIGLNQIIGAYLA 243
+ + +V +R A FT ++ + +A+ A G++ +GA+ A
Sbjct: 203 MIFGGRRVVPWVLERIA-----ASGSRELFTLAVLAIALGIAYGSAVLFGVSFALGAFFA 257
Query: 244 GLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGLMFQPNVREISVLMI 303
G M++ +L+ +E + L + F LFF+ VG++F P + L +
Sbjct: 258 G------------MILNESELSHEAAENSLPLRDAFAVLFFVSVGMLFNPMILLQEPLTV 305
Query: 304 ALLYLAAILGKLIGCGLGMLLFGSSLRDAIIVGVGMGGRGSLELAILKLGLEKGLINESL 363
+L + GK + L + FG A+++ + G ++ LG+ L+ E
Sbjct: 306 LATFLVIVFGKSVAAYLIVRAFGHPNSTALVIAASLAQIGEFSFILIGLGIGLELVPEQS 365
Query: 364 FATIVIVSMLTALSTPIFFRGVIR 387
++ ++L+ L P+ F + R
Sbjct: 366 RDLVLAGAILSILVNPLLFIAIDR 389
>gb|AAK40705.1| Na(+)/H(+) antiporter [Sulfolobus solfataricus]
Length = 505
Score = 86.6 bits (211), Expect = 4e-16
Identities = 81/381 (21%), Positives = 162/381 (42%), Gaps = 31/381 (8%)
Query: 7 LSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFGLIMMML 66
L I+L+ AK E + ++ G+ + IL GI+LG +++ +E + + G++ ++
Sbjct: 12 LGIMLIAAKISEEIFRRIGLVTFVGPILMGILLGNGVFGVIQINEIISFITSLGIVFLLF 71
Query: 67 YMGLTSNFSAISRNKVKATIVATLGVAFSFILGFSTVYFIERNMIAALFVGITLGNTAIE 126
G F+ +R + L F + +Y I L V + + +
Sbjct: 72 LAG-AEEFNVENRPNANVFLAVILESIIPFSVILVAIYIIGFKNYLILIVPLAMSSAG-- 128
Query: 127 VTSGVLVRERVK-KEISSVLMGAAFADDIIAVYLIGLLTGITQGSFSLYPMVVLTIKIVV 185
S +L+ ++ IS+++ +II V L +L ++ +++ I+I +
Sbjct: 129 PLSRMLMDVKISDNRISNLIFQQVILIEIIFVILFAILLKTSE-------ILITIIEIFL 181
Query: 186 FIVATLLISEFVFKRSARFYNVVKDLHVFFTFTIILTFMLAFLAEDIGLNQIIGAYLAGL 245
T++ + K + K + F I + ++ +LAE N I A+ G+
Sbjct: 182 VFAFTIMFGRTLAKILEKIEYYFKAREIEFASLIAIILIIGYLAELYKFNSAISAFFLGI 241
Query: 246 TI-SRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGLMFQPNVREISVLMIA 304
+ L++R EL+ L FF PLFF+ +GL S+++ +
Sbjct: 242 LLKDYLKDRP-----------ELLERLHAFTYGFFEPLFFLGIGLYV--TKINASIILFS 288
Query: 305 LLYLAAILGKLIGCGLGMLLFGSSLRD--AIIVGVGMGGRGSLELAILKLGLEKGLINES 362
LL+ + I+ G S + + I G +G ++ ++L GL G INE
Sbjct: 289 LLFFSLIIASKFLAG----FISSKILNIKGKINGFATSVKGGVDSSLLLTGLTLGYINEF 344
Query: 363 LFATIVIVSMLTALSTPIFFR 383
+++ ++ L+AL P+ F+
Sbjct: 345 MYSFSILAISLSALIVPLLFQ 365
>pir||T50062 Probable K+/H+-antiporter [imported] - fission yeast
(Schizosaccharomyces pombe) >gi|7160220|emb|CAB76234.1|
(AL157994) Probable K+/H+-antiporter
[Schizosaccharomyces pombe]
Length = 898
Score = 86.6 bits (211), Expect = 4e-16
Identities = 82/380 (21%), Positives = 161/380 (41%), Gaps = 49/380 (12%)
Query: 29 IIAHILTGIILGPFGLAIVK-------PSEE---LKVLGEFGLIMMMLYMGLTSNFSAIS 78
+IA I+ GI+LGP + + P+ L ++ GL++ + +G+ + +
Sbjct: 59 VIAEIIGGIVLGPTVMGRIPKFLDYIFPTSSMGPLNLVSNLGLVLFLFVIGMEVDLRVLV 118
Query: 79 RNKVKATIVATLGVAFSFILGFSTVYFIERNMIA-----------ALFVGITLGNTAIEV 127
N K T++ T+ FS ++ F I + LF+ + TA V
Sbjct: 119 LN-YKVTLLVTV---FSIVIPFGAGAGISAGLYKFTTREFEFGKFLLFISTAMSITAFPV 174
Query: 128 TSGVLVR-ERVKKEISSVLMGAAFADDIIAVYLIGLLTGITQGSFSLYPMVVLTIKIVVF 186
+ +L + K + +++ A +D+I L+ L + + + +L + +
Sbjct: 175 LARILSELHLLHKRVGVIVLSAGIGNDVIGWILLALSVTLVNSGSGVRAVYILLLALGWC 234
Query: 187 IVATLLISEFVFKRSARFYNVV-KDLHVFFTFTIILTFMLAFLAEDIGLNQIIGAYLAGL 245
+ + I V+ + + ++ K F + + + AF + IG++ I G +L G
Sbjct: 235 LFLFIAIKPLVYLLAVKTRSLKDKPSESFICIVLSMVLVSAFFTDIIGIHPIFGGFLVGT 294
Query: 246 TISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGLMFQPNVREISVLMIAL 305
I + +K+ E I +L L F+PL+F GL IS L
Sbjct: 295 IIPHEND-------LTVKITEKIEDLVNCL---FLPLYFASSGLK-----TNISTLNTGK 339
Query: 306 LY-------LAAILGKLIGCGLGMLLFGSSLRDAIIVGVGMGGRGSLELAILKLGLEKGL 358
++ AI K+ L + D+++VG M +G +EL +L +GL G+
Sbjct: 340 IWGYTIGTICVAIASKMGSSMLAARILKMPWSDSLVVGSLMSCKGLVELIVLNIGLSTGI 399
Query: 359 INESLFATIVIVSMLTALST 378
+NE++F+ V ++++T T
Sbjct: 400 LNETIFSMFVFMAVITTFVT 419
>pir||F82595 glutathione-regulated potassium efflux system protein XF2140
[imported] - Xylella fastidiosa (strain 9a5c)
>gi|9107273|gb|AAF84939.1|AE004028_7 (AE004028)
cation:proton antiporter [Xylella fastidiosa]
Length = 572
Score = 84.7 bits (206), Expect = 2e-15
Identities = 78/396 (19%), Positives = 164/396 (40%), Gaps = 32/396 (8%)
Query: 7 LSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFGLIMMML 66
+++ L +A L L ++ + P++ +++ GI +GPF V + L E G++++M
Sbjct: 11 IAVGLSLAFVLGALAQRLKLSPLVGYLVAGICVGPFTPGFVADQQIANQLSELGVMLLMF 70
Query: 67 YMGLTSNFSAISRNKVKATIVATLGVAFSFILGFSTVYFIERNMIAALFVGITLGNTAIE 126
+GL + + K A A + +A + +LG+ + + M+ + G+ L +
Sbjct: 71 GVGLHFSLEDLLEVKAIAIPGALVQIAAATLLGWGLAWTMGWPMVQGVVFGLALSVASTV 130
Query: 127 VTSGVLVRER-VKKEISSVLMGAAFADDIIAVYLIGLLTGITQ----------------- 168
V L R + + + +G +D++ V + LL + Q
Sbjct: 131 VLLRALEERRLIDTQRGRIAVGWLIVEDLVMVLALVLLPALAQMLNGNESVAAHTPNGSS 190
Query: 169 -GSFSLYPMVVLTIKIVVFIVATLLISEFVFKRSARFYNVVKDLHVFFTFTIILTFMLAF 227
G+ L + +K+ F+ L++ V S +F + + +AF
Sbjct: 191 DGNAMLTALGWTLLKMAGFVAVMLVVGRRVIPWSLEKVAATGSRELFTLAVLGIALGVAF 250
Query: 228 -LAEDIGLNQIIGAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIY 286
A+ G++ +GA+ AG MV+ + + + + L + F LFF+
Sbjct: 251 GSAKLFGVSFALGAFFAG------------MVLKGSETSHAAATDSLPLRDAFAVLFFVA 298
Query: 287 VGLMFQPNVREISVLMIALLYLAAILGKLIGCGLGMLLFGSSLRDAIIVGVGMGGRGSLE 346
VG++F P + L + +L +GK L + FG A+ + + G
Sbjct: 299 VGMLFNPAILIEHPLQVLATFLTITIGKSAAAFLIVRAFGHPTSTALTISTSLAQIGEFS 358
Query: 347 LAILKLGLEKGLINESLFATIVIVSMLTALSTPIFF 382
+ LG++ ++ E+ I+ ++L+ ++ P F
Sbjct: 359 FILAGLGIQLAILPETGRDLILAGALLSIIANPFLF 394
>pir||A81330 probable glutathione-regulated potassium-efflux system protein
Cj1231 [imported] - Campylobacter jejuni (strain NCTC
11168) >gi|6968664|emb|CAB73485.1| (AL139077) putative
glutathione-regulated potassium-efflux system protein
[Campylobacter jejuni]
Length = 541
Score = 81.9 bits (199), Expect = 1e-14
Identities = 88/393 (22%), Positives = 163/393 (41%), Gaps = 21/393 (5%)
Query: 2 NYIFDLSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFGL 61
N++ I + +A L + KK + II +I G I+ + + E+ + EFG+
Sbjct: 3 NFLEIFLITVAIAIVLNVIFKKFEIPTIIGYIAAGEIISE--IYHLSGKGEITHIAEFGI 60
Query: 62 IMMMLYMGLTSNFSAISRNKVKATIVATLGV-AFSFILGFSTVYFIERNMIAALFVGITL 120
+ +M +GL +F + K + + +L + F+ + + +A VG L
Sbjct: 61 VFLMFTIGLEFSFKHLMAMKQEVFLNGSLQMLTCGFVFMLLAIGILGLGDKSATIVGFAL 120
Query: 121 GNTAIEVTSGVLVRER-VKKEISSVLMGAAFADDIIAVYLIGLLTGITQGSFSLYPMVVL 179
++ V +L + ++ +G DI + L+ LL I + ++
Sbjct: 121 ALSSTAVVLKILNDNGDINEQYGRKALGILLFQDIAVIPLL-LLVDIFSSNNQNIEKLLF 179
Query: 180 TIKIVVFIVATLL--ISEFVFKRSARFYNVVKDLHVFFTFTIILTFMLAFLAEDIGLNQI 237
T I I+ TLL I +++ R R +F + + + +FLA G +
Sbjct: 180 TSLISALILITLLFFIGKYLVDRIFRLIIHTSSQEIFISTVLFMVIGASFLANYFGFSYS 239
Query: 238 IGAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGLMFQPNVRE 297
+GA++AG +I K I + + + LFFI VG+ Q +V
Sbjct: 240 LGAFIAG------------ALIAETKYKHKIEADLIPFRDLLLGLFFITVGMQIQLDVVA 287
Query: 298 ISVLMIALLYLAAILGKLIGCGLGMLLFGSSLRDAIIVGVGMGGRGSLELAILKLGLEKG 357
+ +I +L L ++ G G L + R A+ + G LAI L K
Sbjct: 288 QNWFLIIVLTL-LVMALKFGIVFGFLFLYTKKRVALKTAFAIAQIGEFALAIFSLLQAKN 346
Query: 358 LINESLFATIVIVSMLTALSTPIFFRGVIRKLS 390
+++ +++VS+LT + TP F IRK++
Sbjct: 347 MLDIKTSQILIVVSILTMIITP-FILNNIRKIT 378
>pir||G69819 Na+/H+ antiporter homolog yhaU - Bacillus subtilis
>gi|2226151|emb|CAA74453.1| (Y14080) hypothetical
protein [Bacillus subtilis] >gi|2633321|emb|CAB12825.1|
(Z99109) similar to Na+/H+ antiporter [Bacillus
subtilis]
Length = 408
Score = 81.5 bits (198), Expect = 1e-14
Identities = 87/373 (23%), Positives = 157/373 (41%), Gaps = 40/373 (10%)
Query: 4 IFDLSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFG-------LAIVKPSEELKVL 56
+F++ LV+ + K I I+ G+++GP L ++ SE ++
Sbjct: 8 VFEVGTALVLVAIASVIANKIKFSIIPFLIVLGMLVGPHAPKMGIIDLTFIQSSEIIEFF 67
Query: 57 GEFGLIMMMLYMGLTSNFSAISRNKVKATIVAT--------LGVAFSFILGFSTVYFIER 108
G G++ ++ Y+GL + + ++ + T LG+ + FI GFS F+E
Sbjct: 68 GRMGVLFLLFYLGLEFSVGKLIKSGKSIAVGGTIYILINFSLGLLYGFITGFS---FLEV 124
Query: 109 NMIAALFVGITLGNTAIEVTSGVLVRERVKKEISSVLMGAAFADDIIAVYLIGLLTGITQ 168
++A + IT+ ++AI V ++ E +L F D +AVYL +++G+
Sbjct: 125 LILAGV---ITISSSAIVAKVLVDLKRTANPETELILGIIMFEDIFLAVYL-SVVSGLIL 180
Query: 169 GSFSLYPMVVLTIKIVVFIVATLLISEFVFKRSARFYNVVKDLHVFFTFTIILTFMLAFL 228
G + +L+I I + I+ ++ N + D+ F I++ L F+
Sbjct: 181 GDATSVGSALLSILIAFGYMLLFFIAA---RKLPPLLNKLLDIRSNEVFIIVIFAALFFI 237
Query: 229 A---EDIGLNQIIGAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFI 285
A E I + + IGA L GL S ++ I L V +FF +FF
Sbjct: 238 AGFSETIHVAEAIGALLLGLVFSETEH------------SDRIEHLVVPFRDFFGAMFFF 285
Query: 286 YVGLMFQPNVREISVLMIALLYLAAILGKLIGCGLGMLLFGSSLRDAIIVGVGMGGRGSL 345
GL P +V + + ILG I + G S + + +G+ + RG
Sbjct: 286 SFGLSIDPFSLGEAVWLALGAVILTILGNFIAGMVAGRRAGLSHKASSNIGLTIVSRGEF 345
Query: 346 ELAILKLGLEKGL 358
+ + LG+ GL
Sbjct: 346 SIIVANLGIAGGL 358
>pir||B82056 glutathione-regulated potassium-efflux system protein KefB VC2606
[imported] - Vibrio cholerae (group O1 strain N16961)
>gi|9657194|gb|AAF95747.1| (AE004327)
glutathione-regulated potassium-efflux system protein
KefB [Vibrio cholerae]
Length = 656
Score = 80.8 bits (196), Expect = 3e-14
Identities = 73/365 (20%), Positives = 156/365 (42%), Gaps = 22/365 (6%)
Query: 20 LLKKRGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFGLIMMMLYMGLTSNFSAISR 79
L ++ G+ ++ ++L GI +GP+GL +++ + + EFG+++++ +GL N +
Sbjct: 81 LAQRAGLGSVLGYLLAGIAIGPWGLGLIRDVQAIMHFAEFGVVLLLFLIGLELNPKKLWN 140
Query: 80 NKVKATIVATLGVAFSFILGFSTVYFIERNMIAALFVGITLGNTAIEVTSGVLVRERV-K 138
+ + V + + S Y + + +AL +G+ L ++ + V+ + +
Sbjct: 141 LRGPILGLGGAQVVVTTAVLSSVAYLLGVSWQSALVIGMALALSSTAIALRVIEEHGLTR 200
Query: 139 KEISSVLMGAAFADDIIAVYLIGLLTGITQGSFSLYPMVVLTIKIVVFIVATLLISEFVF 198
E DI + ++ LL + S + + + + I A LL F+
Sbjct: 201 TEAGQSGFAVLLFQDIAVIPMLALLPILAGNSSGDW---LNALWMTGGIAALLLGGHFLL 257
Query: 199 KRSARFYNVVKDLHVFFTFTIILTFMLAFLAEDIGLNQIIGAYLAGLTISRLRERKDPMV 258
R+ + +F ++L +A L + +GL+ +G +LAG+ ++
Sbjct: 258 NPLFRYIALSGVRELFTVAALLLVVGIALLMQKVGLSMALGTFLAGVILAE--------- 308
Query: 259 ITRIKLNELISELEVVLLEF---FIPLFFIYVGLMFQPNVREISVLMIALLYLAAILGKL 315
+E ELE+ + F + LFFI VG+ + + L I L L ++ K
Sbjct: 309 ------SEFRHELEIAIDPFKGLLLGLFFISVGMAVDVGLLLVKPLQIMLAVLGLVIVKG 362
Query: 316 IGCGLGMLLFGSSLRDAIIVGVGMGGRGSLELAILKLGLEKGLINESLFATIVIVSMLTA 375
+ L L G+ + + + G I +GL+ S + +++V L+
Sbjct: 363 LVLYLLARLSGTVAKARSKMAAILSQGGEFAFVIFTAASAEGLLTASQVSFLLVVVSLSM 422
Query: 376 LSTPI 380
++TP+
Sbjct: 423 VTTPL 427
>pir||G75282 probable glutathione-regulated potassium-efflux system protein KefB
- Deinococcus radiodurans (strain R1)
>gi|6460182|gb|AAF11914.1|AE002067_6 (AE002067)
glutathione-regulated potassium-efflux system protein
KefB, putative [Deinococcus radiodurans]
Length = 575
Score = 79.2 bits (192), Expect = 8e-14
Identities = 94/398 (23%), Positives = 167/398 (41%), Gaps = 47/398 (11%)
Query: 3 YIFDLSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFGLI 62
++ L++LL+VA + + + G+ PII + G++ GP L I+ + E G++
Sbjct: 35 FMGQLTLLLLVAGATAFASFRLGLVPIIGFLFAGVLAGPSALGIIDDPALIGAASEIGVM 94
Query: 63 MMMLYMGLTSNFSAISR----------NKVKATIVATLGVAFSFILGFSTVYFIERNMIA 112
+++ +G+ + ++R +V T+ A GV +F +
Sbjct: 95 LLLFTIGIEFSLDKLARIFRLIFVGGGLQVLLTVAAVTGVLLAFGVSLPN---------- 144
Query: 113 ALFVG--ITLGNTAIEVTSGVLVRERVKKEISSVLMGAAFADD---IIAVYLIGLLTGIT 167
A+F G ++L +TAI VT + R V +G D ++ V L+ +L G
Sbjct: 145 AVFTGFLLSLSSTAI-VTKILESRGGVGSPTGQASLGILIFQDLAVVVMVLLVPMLAGQG 203
Query: 168 QGSFSLYPMVVLTIKIVVFIVATLLISEFVFKRSARFYNVVKDLHVFFTFTIILTFMLAF 227
G+ L VV +K + A LL++ V + +F T+ L F A+
Sbjct: 204 GGAGGL---VVALLKAGGIVAAVLLLARRVVPKLLEVVARTCSQEIFLLSTLSLCFATAY 260
Query: 228 LAEDIGLNQIIGAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYV 287
L G++ +GA+LAGL +S R + + E+ + L F FF+ V
Sbjct: 261 LTSLAGVSLALGAFLAGLLVSESRFGQ-----------QAFGEI-LPLQILFSAAFFLSV 308
Query: 288 GLMFQPNVREISV-LMIALLYLAAILGKLIGCGLGMLLFGSSLRDAIIVGVGMGGRGS-- 344
GL + L++ + + A+L K + L + L G L A G + G
Sbjct: 309 GLQLDLGFLWTHLPLVLGAVAVFAVL-KALAAALSVRLLGFPLATAAATGWLLAQVGEFS 367
Query: 345 --LELAILKLGLEKGLINESLFATIVIVSMLTALSTPI 380
LE + LGL + E+ T + ++L TP+
Sbjct: 368 FVLESSGRALGLSPAGLGETGTQTFIAATVLLMALTPV 405
>sp|P45522|KEFB_ECOLI GLUTATHIONE-REGULATED POTASSIUM-EFFLUX SYSTEM PROTEIN KEFB
(K(+)/H(+) ANTIPORTER) (NEM-ACTIVATABLE K+/H+
ANTIPORTER) >gi|7444645|pir||A65129
glutathione-regulated potassium-efflux system protein
kefB - Escherichia coli (strain K-12)
>gi|606284|gb|AAA58147.1| (U18997) ORF_f601 [Escherichia
coli] >gi|1789749|gb|AAC76375.1| (AE000411) K+ efflux;
NEM-activable K+/H+ antiporter [Escherichia coli K12]
Length = 601
Score = 78.4 bits (190), Expect = 1e-13
Identities = 84/392 (21%), Positives = 165/392 (41%), Gaps = 32/392 (8%)
Query: 9 ILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFGLIMMMLYM 68
+ L A + L + G+ ++ ++L GI +GP+GL + +E+ E G++ +M +
Sbjct: 12 LFLFAAVAAVPLASRLGIGAVLGYLLAGIAIGPWGLGFISDVDEILHFSELGVVFLMFII 71
Query: 69 GLTSNFSAISRNKVKATIVATLGVAFSFILGFSTVYFIERNMIAALF--VGITLGNTAIE 126
GL N S + + + V V S L + + AA+ +G+ + +TA+
Sbjct: 72 GLELNPSKLWQLRRSIFGVGAAQVLLSAALLAGLLMLTDFAWQAAVVGGIGLAMSSTAMA 131
Query: 127 VTSGVLVRERVKKEISSVLMGAA---FAD--DIIAVYLIGLLTGITQGSFSLYPMVVLTI 181
+ L+RE+ S +G + F D I A+ L+ LL G F + + +
Sbjct: 132 LQ---LMREKGMNRSESGQLGFSVLLFQDLAVIPALALVPLLAGSADEHFD---WMKVGM 185
Query: 182 KIVVFIVATLLISEFVFKRSARFYNVVKDLHVFFTFTIILTFMLAFLAEDIGLNQIIGAY 241
K++ F V L+ ++ + RF VF T++L A + +GL+ +G +
Sbjct: 186 KVLAF-VGMLIGGRYLLRPVFRFIAASGVREVFTAATLLLVLGSALFMDALGLSMALGTF 244
Query: 242 LAGLTISRLRERKDPMVITRIKLNELISELEVVLLEF---FIPLFFIYVGLMFQPNVREI 298
+AG+ ++ +E ELE + F + LFFI VG+ V
Sbjct: 245 IAGVLLAE---------------SEYRHELETAIDPFKGLLLGLFFISVGMSLNLGVLYT 289
Query: 299 SVLMIALLYLAAILGKLIGCGLGMLLFGSSLRDAIIVGVGMGGRGSLELAILKLGLEKGL 358
+L + + + + K++ L L+G + + + G + + L
Sbjct: 290 HLLWVVISVVVLVAVKILVLYLLARLYGVRSSERMQFAGVLSQGGEFAFVLFSTASSQRL 349
Query: 359 INESLFATIVIVSMLTALSTPIFFRGVIRKLS 390
A +++ L+ ++TP+ + V + LS
Sbjct: 350 FQGDQMALLLVTVTLSMMTTPLLMKLVDKWLS 381
>pir||C83496 glutathione-regulated potassium-efflux system protein KefB PA1207
[imported] - Pseudomonas aeruginosa (strain PAO1)
>gi|9947134|gb|AAG04596.1|AE004550_12 (AE004550)
glutathione-regulated potassium-efflux system protein
KefB [Pseudomonas aeruginosa]
Length = 613
Score = 78.0 bits (189), Expect = 2e-13
Identities = 93/397 (23%), Positives = 178/397 (44%), Gaps = 38/397 (9%)
Query: 9 ILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFGLIMMMLYM 68
+ L+ A + L K+ + ++ ++L G+++GP L +V E + + E G+++++ +
Sbjct: 13 VFLIAAVFMVPLAKRLQLGAVLGYLLAGVLIGPSVLGLVDNPESVAQISEMGVVLLLFII 72
Query: 69 GLTSNFSAISRNKVKATIVATLGVAFS-FILGFSTVYFIER--NMIAALFVGITLGNTAI 125
GL + + + V L V + ++G + ++ N L +G+ L +TA
Sbjct: 73 GLELSPRRLWVMRKSVFGVGLLQVLLTGLVIGTVALVGFDQPVNSAVVLGLGLALSSTAF 132
Query: 126 EVTSGVLVRERVKKEISSVLMGAAFA----DDIIAVYLIGLLTGITQG-SFSLYPMVVLT 180
+ ++ ER KE++ AFA DI A+ LI ++ ++ S + + T
Sbjct: 133 GLQ---ILAER--KELTQPHGRLAFAILLFQDIAAIPLIAMIPLLSGAHSDAGGSELTQT 187
Query: 181 IKIVVFIVATLLISEFVFKRSARFYNVVKDLHVFFTFTIILTFM-LAFLAEDIGLNQIIG 239
+K+V I A ++ ++ + R K L T T +L M A L E G++ +G
Sbjct: 188 LKVVGSIAAVVVGGRYLLRPVFRIVAQTK-LQDMSTATALLVVMGTALLMELAGVSMALG 246
Query: 240 AYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGLMFQPNVREIS 299
A+LAGL ++ R +EL +++E + LFFI VG+ +IS
Sbjct: 247 AFLAGLLLADSEYR-----------HELEAQIE-PFKGLLLGLFFISVGMS-----ADIS 289
Query: 300 VLM------IALLYLAAILGKLIGCGLGMLLFGSSLRDAIIVGVGMGGRGSLELAILKLG 353
+L+ + L L L + +G + G A+ +GV + G + K+
Sbjct: 290 LLLKSPWMVLGLTVLLIALKAPVLYFVGRISGGLDKASALRLGVVLAAGGEFAFVVFKMA 349
Query: 354 LEKGLINESLFATIVIVSMLTALSTPIFFRGVIRKLS 390
++GL L +V+ L+ TP+ G+ R L+
Sbjct: 350 RDQGLFQNDLHNLLVLSITLSMALTPLLVLGLARLLA 386
>gb|AAD01191.1| (AF003382) KEA1 [Arabidopsis thaliana]
Length = 618
Score = 77.3 bits (187), Expect = 3e-13
Identities = 86/399 (21%), Positives = 173/399 (42%), Gaps = 47/399 (11%)
Query: 4 IFDLSILLVVAKSLEWLLKK-RGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFGLI 62
+FD LL+ + L +K G P++ ++ GI++GP+GL+I++ + + EFG++
Sbjct: 14 LFDFLWLLLASVIFVPLFQKIPGGSPVLGYLAAGILIGPYGLSIIRNVHGTRAIAEFGVV 73
Query: 63 MMMLYMGLTSNFSAISRNKVKATIVATLGV-AFSFILGFSTVYFIERNMIAALFVGITLG 121
+++ +GL + +S K + + V + ++G Y + AA+ +G
Sbjct: 74 LLLFNIGLELSVERLSSMKKYVFGLGSAQVLVTAAVVGLLAHYVAGQAGPAAIVIG---N 130
Query: 122 NTAIEVTSGVLVRERVKKEISSVLMGAAFA----DDIIAVYLIGLLTGITQGSFS----- 172
A+ T+ VL + + E +S A+F+ D+ V L+ L+ I+ S
Sbjct: 131 GLALSSTAVVLQVLQERGESTSRHGRASFSVLLFQDLAVVVLLILIPLISPNSSKGGIGF 190
Query: 173 ---LYPMVVLTIKIVVFIVATLLISEFVFKRSARFYNVVKDLHVFFTFTIILTFMLAFLA 229
+ + +K V I A + + + + ++ +F T+++ + L
Sbjct: 191 QAIAEALGLAAVKAAVAITAIIAGGRLLLRPIYKQIAENRNAEIFSANTLLVILGTSLLT 250
Query: 230 EDIGLNQIIGAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGL 289
GL+ +GA+LAGL ++ +++ I+ +LL LFF+ VG+
Sbjct: 251 ARAGLSMALGAFLAGLLLAETE--------FSLQVESDIAPYRGLLL----GLFFMTVGM 298
Query: 290 MFQPN---------VREISVLMIALLYLAAILGKLIGCGLGMLLFGSSLRDAIIVGVGMG 340
P V + +L++ L I+GK LFG S+ AI VG+ +
Sbjct: 299 SIDPKLLLSNFPVIVGTLGLLIVGKTMLVVIMGK---------LFGISIISAIRVGLLLA 349
Query: 341 GRGSLELAILKLGLEKGLINESLFATIVIVSMLTALSTP 379
G + +G+++ L + + +V ++ TP
Sbjct: 350 PGGEFAFVAFGEAVNQGIMSPQLSSLLFLVVGISMAITP 388
>pir||A72473 probable Na+/H+ antiporter APE2426 - Aeropyrum pernix (strain K1)
>gi|5106130|dbj|BAA81441.1| (AP000064) 412aa long
hypothetical Na+/H+ antiporter [Aeropyrum pernix]
Length = 412
Score = 76.9 bits (186), Expect = 4e-13
Identities = 81/384 (21%), Positives = 167/384 (43%), Gaps = 34/384 (8%)
Query: 1 MNYIFDLSILLVVAKSLEWLLKKR-----GVHPIIAHILTGIILGPFGLAIVKPSEELKV 55
+ + + IL++V + L R G+ P + I+ G +L +G VK +E L +
Sbjct: 50 LEFEVEYDILVIVLVAFYILAATRIAHVIGLPPGVVEIIMGAMLAFWG---VKSTEVLTL 106
Query: 56 LGEFGLIMMMLYMGLTSNFSAISRNKVKATIVATLGVAFSFILGFSTVYFIERNMIAALF 115
L G +++ G + + + +A IVA + L ++ ++ ++L
Sbjct: 107 LAAIGANLLLFMAGSEIDLALLRSILPQAVIVALVSALAPLALTALLHVYLGLSLTSSLV 166
Query: 116 VGITLGNTAIEVTSGVLVRER-VKKEISSVLMGAAFADDIIAVYLIGLLTGITQGSFSLY 174
+ +L T++ +T +L R V+ + + + +A D+ + ++ + T S + Y
Sbjct: 167 ILASLSATSVALTYLLLSSYRLVRSRLGQLALASAMLLDLSGMIMLNIATASISPSLAFY 226
Query: 175 PMVVLTIKIVVFIVATLLISEFVFKRSARFYNVVKDLHVFFTFTIILTFMLAFLAEDIGL 234
IV+ + A LL A F ++ T T+I+ L FL++ +G+
Sbjct: 227 --------IVILLAALLLYPLLPRLGGAPFEAEIR----LITMTVII---LGFLSDFVGV 271
Query: 235 NQIIGAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGLMFQPN 294
+ ++ +++ G+ S V TR++L E +LE + FF P FFI G+ P
Sbjct: 272 HSVLTSFILGVIASET-------VRTRVQLRE---KLESLATGFFTPFFFIASGMSIDPG 321
Query: 295 VREISVLMIALLYLAAILGKLIGCGLGMLLFGSSLRDAIIVGVGMGGRGSLELAILKLGL 354
+ V + +A L + L GSS R ++I ++ + +G
Sbjct: 322 IPLHYVALALAGGVALALARTYTVYFYFRLTGSSRRSSLIAASSTAMLLTVTIIAASVGF 381
Query: 355 EKGLINESLFATIVIVSMLTALST 378
+ GL++ +++ +V + + T L +
Sbjct: 382 QLGLLDSLMYSVLVWIVVGTILGS 405
>gb|AAF78418.1|AC009273_24 (AC009273) Identical to K efflux antiporter mRNA from Arabidopsis
thaliana gb|AF003382. It contains a TrkA potassium
uptake protein PF|02080 domain. ESTs gb|T44799,
gb|AA395270 and gb|AI997899 come from this gene
Length = 618
Score = 76.5 bits (185), Expect = 5e-13
Identities = 86/399 (21%), Positives = 172/399 (42%), Gaps = 47/399 (11%)
Query: 4 IFDLSILLVVAKSLEWLLKK-RGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFGLI 62
+FD LL+ + L +K G P++ ++ GI++GP+GL+I++ + + EFG++
Sbjct: 14 LFDFLWLLLASVIFVPLFQKIPGGSPVLGYLAAGILIGPYGLSIIRNVHGTRAIAEFGVV 73
Query: 63 MMMLYMGLTSNFSAISRNKVKATIVATLGV-AFSFILGFSTVYFIERNMIAALFVGITLG 121
++ +GL + +S K + + V + ++G Y + AA+ +G
Sbjct: 74 FLLFNIGLELSVERLSSMKKYVFGLGSAQVLVTAAVVGLLAHYVAGQAGPAAIVIG---N 130
Query: 122 NTAIEVTSGVLVRERVKKEISSVLMGAAFA----DDIIAVYLIGLLTGITQGSFS----- 172
A+ T+ VL + + E +S A+F+ D+ V L+ L+ I+ S
Sbjct: 131 GLALSSTAVVLQVLQERGESTSRHGRASFSVLLFQDLAVVVLLILIPLISPNSSKGGIGF 190
Query: 173 ---LYPMVVLTIKIVVFIVATLLISEFVFKRSARFYNVVKDLHVFFTFTIILTFMLAFLA 229
+ + +K V I A + + + + ++ +F T+++ + L
Sbjct: 191 QAIAEALGLAAVKAAVAITAIIAGGRLLLRPIYKQIAENRNAEIFSANTLLVILGTSLLT 250
Query: 230 EDIGLNQIIGAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGL 289
GL+ +GA+LAGL ++ +++ I+ +LL LFF+ VG+
Sbjct: 251 ARAGLSMALGAFLAGLLLAETE--------FSLQVESDIAPYRGLLL----GLFFMTVGM 298
Query: 290 MFQPN---------VREISVLMIALLYLAAILGKLIGCGLGMLLFGSSLRDAIIVGVGMG 340
P V + +L++ L I+GK LFG S+ AI VG+ +
Sbjct: 299 SIDPKLLLSNFPVIVGTLGLLIVGKTMLVVIMGK---------LFGISIISAIRVGLLLA 349
Query: 341 GRGSLELAILKLGLEKGLINESLFATIVIVSMLTALSTP 379
G + +G+++ L + + +V ++ TP
Sbjct: 350 PGGEFAFVAFGEAVNQGIMSPQLSSLLFLVVGISMAITP 388
>gb|AAC60780.1| (U46859) RosB [Yersinia enterocolitica (type 0:8)]
Length = 563
Score = 75.7 bits (183), Expect = 9e-13
Identities = 80/392 (20%), Positives = 164/392 (41%), Gaps = 26/392 (6%)
Query: 11 LVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFGLIMMMLYMGL 70
LV+A L L + P++ ++ G++ GPF V + L E G+I++M +GL
Sbjct: 15 LVLAFLLGSLAHRLRSSPLVGYLAAGVLAGPFTPGFVADTSLAPELAEIGVILLMFGVGL 74
Query: 71 TSNFSAISRNKVKATIVATLGVAFSFILGFSTVYFIERNMIAALFVGITLGNTAIEVTSG 130
+ + K A A +A + +LG + + +++ G+ L + V
Sbjct: 75 HFSLKDLLAVKAIAIPGAVAQIAVATLLGMGLSHLLGWDLMTGFVFGLCLSTASTVVLLR 134
Query: 131 VL-VRERVKKEISSVLMGAAFADDIIAVYLI-------GLLTGITQGSFSLYPMVVLTI- 181
L R+ + + + +G + +D+ V + G++ T L+ + +TI
Sbjct: 135 ALEERQLIDSQRGQIAIGRSIVEDLAMVLTLVLLPAFAGVMGNETTSLSQLFTELAITIG 194
Query: 182 KIVVFIVATLLISEFVFKRSARFYNVVKDLHVFFTFTIILTFMLAFLAEDIGLNQI---I 238
K++ FI +++ + +F ++L +A+ A +GL + +
Sbjct: 195 KVIAFITLMIVVGRRLVPWILAKTASTGSRELFTLAVLVLALGIAYGA--VGLFDVSFAL 252
Query: 239 GAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGLMFQPNVREI 298
GA+ AG MV+ +L+ ++ + L + F LFF+ VG++F P +
Sbjct: 253 GAFFAG------------MVLNESELSHRAAQDTLPLRDAFAVLFFVSVGMLFDPMILLR 300
Query: 299 SVLMIALLYLAAILGKLIGCGLGMLLFGSSLRDAIIVGVGMGGRGSLELAILKLGLEKGL 358
L + I GK + + +FG S + +L + LG+ GL
Sbjct: 301 EPLAVLASLAIIIFGKSAAAFILVRMFGHSNVYSTHHFCPWRKSVNLPFILAGLGISLGL 360
Query: 359 INESLFATIVIVSMLTALSTPIFFRGVIRKLS 390
++E ++ ++L+ + P+ F + R L+
Sbjct: 361 MSEHGRNLVLAGAILSIMLNPLLFTLLDRYLA 392
>pir||C81997 probable glutathione-regulated potassium-efflux system protein
NMA0060 [imported] - Neisseria meningitidis (group A
strain Z2491) >gi|7378833|emb|CAB83376.1| (AL162752)
putative transmembrane transport protein [Neisseria
meningitidis Z2491]
Length = 658
Score = 75.7 bits (183), Expect = 9e-13
Identities = 88/385 (22%), Positives = 171/385 (43%), Gaps = 42/385 (10%)
Query: 9 ILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFGLIMMMLYM 68
I+L+V+ L +K + ++ ++L G + GP L+++ S LGE G++ +M +
Sbjct: 11 IVLLVSVITVILCRKFNIPSMLGYLLVGFLAGPGMLSLIPKSHATDYLGEIGIVFLMFSI 70
Query: 69 GLTSNFSAI--SRNKVKATIVATLGVAFSFILGFSTVYFIERNMIAALFVGITLGNTAIE 126
GL + + R V +GV ++G + + N A+ + + +TAI
Sbjct: 71 GLEFSLPKLRAMRRLVFGLGGLQVGVTMLSVMGILMLTGVPFNWAFAVSGALAMSSTAI- 129
Query: 127 VTSGVLVRERVKKEISSVLMGAAFADDIIAVYLIGLLTGITQGSFS--------LYPMVV 178
V+ + + + + + MG DI V L+ L+ + G + ++
Sbjct: 130 VSRILSEKTELGQPHGQMAMGVLLMQDIAVVPLMILIPALAGGGDGNIWAALGLAFAKML 189
Query: 179 LTIKIVVFIVATLLISEFVFKRSARFYNVV---KDLHVFFTFTIILTFMLAFLAEDIGLN 235
LT+ ++ F+ + ++ +R++ +V K +F +++T +A+L E GL+
Sbjct: 190 LTLGLLFFVGSKIM---------SRWFRMVAKRKSSELFMINVLLVTLGVAYLTELEGLS 240
Query: 236 QIIGAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGLMFQPNV 295
+GA++AG+ +S R ++ + I +LL F FFI VG+
Sbjct: 241 MALGAFVAGMLLSETE--------YRFQVEDDIRPFRDILLGF----FFITVGMKLDIQA 288
Query: 296 -----REISVLMIALLYLAAILGKLIGCGLGMLLFGSSLRDAIIVGVGMGGRGSLELAIL 350
R++ +L+ LL L A++ I + + G SL+ A+ + G G G + LAI
Sbjct: 289 LIGGWRQVLMLLAMLLVLKALVVFAIAFKMKHSV-GDSLKTALYLAQG-GEFGFVMLAIA 346
Query: 351 KLGLEKGLINESLFATIVIVSMLTA 375
L E V++SM+ A
Sbjct: 347 GQLDMVSLEWEQAATAAVLLSMIIA 371
>gi|11498844 Na+/H+ antiporter (napA-2) [Archaeoglobus fulgidus]
>gi|7483893|pir||D69405 Na+/H+ antiporter (napA-2)
homolog - Archaeoglobus fulgidus
>gi|2649335|gb|AAB89998.1| (AE001018) Na+/H+ antiporter
(napA-2) [Archaeoglobus fulgidus]
Length = 338
Score = 74.9 bits (181), Expect = 1e-12
Identities = 76/331 (22%), Positives = 151/331 (44%), Gaps = 38/331 (11%)
Query: 6 DLSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFGLIMMM 65
+L++++ A + + + PI A+IL G+ LG G + E++ LG+ G++ ++
Sbjct: 2 ELAVIVFAAAIAAIISRMLRITPIPAYILVGMALGKAGWHL----SEVEFLGKLGIVFLL 57
Query: 66 LYMGLTSNFSAISRNKVKATIVATLGVAFSFILGFSTVYFIERNMIAALFVGITLGNTAI 125
Y+GL S I + + T+ F+F+ +Y I ++ A + + ++
Sbjct: 58 FYVGLKIPPSTIKKTWQRTLKSGTIDFLFNFLPPLVLLYLIGFDLRDAFILASAIYISSS 117
Query: 126 EVTSGVLVRER-VKKEISSVLMGAAFADDIIAVYLIGLLTGITQGSFSLYPMVVLTIKIV 184
+ +LV +R + + V++ +DI+ V L+ L + + ++ LT
Sbjct: 118 AINLKMLVDDRKLVFTFAEVVVLLMVFEDIVLVALLFLFSASEPLTLLYLALIALT---- 173
Query: 185 VFIVATLLISEFVFKRSARFYNVVKDLHVFFTFTIILTFMLAFLAEDIGLNQIIGAYLAG 244
+A IS + K +R + V + T + + FLAE +++ + A L G
Sbjct: 174 --ALALYAISPQIEKLMSR------EDEVPYLLTFSIPSISLFLAEKFRISEALMAILFG 225
Query: 245 LTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGLMFQPNVREISVLMIA 304
+ ++RLR I ++ V E F+ +FF++ G M + +S+L+IA
Sbjct: 226 VALNRLR----------------IDKMLVPFKEVFLAVFFVFFGTMVDLHFSYLSLLLIA 269
Query: 305 LLYLAAILGKLIGCGLGMLLFGSSLRDAIIV 335
+ A++GKL G + F +S DA+ V
Sbjct: 270 V----AVIGKLAGAYF-IARFTTSKSDAVEV 295
>pir||B81225 glutathione-regulated potassium-efflux system protein NMB0209
[imported] - Neisseria meningitidis (group B strain
MD58) >gi|7225431|gb|AAF40666.1| (AE002378)
glutathione-regulated potassium-efflux system protein
[Neisseria meningitidis MC58]
Length = 658
Score = 74.5 bits (180), Expect = 2e-12
Identities = 81/359 (22%), Positives = 162/359 (44%), Gaps = 42/359 (11%)
Query: 9 ILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFGLIMMMLYM 68
I+L+V+ L +K + ++ ++L G + GP L+++ S LGE G++ +M +
Sbjct: 11 IVLLVSVITVILCRKFNIPSMLGYLLVGFLAGPGMLSLIPKSHATDYLGEIGIVFLMFSI 70
Query: 69 GLTSNFSAI--SRNKVKATIVATLGVAFSFILGFSTVYFIERNMIAALFVGITLGNTAIE 126
GL + + R V +G+ ++G + + N A+ + + +TAI
Sbjct: 71 GLEFSLPKLRAMRRLVFGLGGLQVGITMLSVMGILMLTGVPFNWAFAVSGALAMSSTAI- 129
Query: 127 VTSGVLVRERVKKEISSVLMGAAFADDIIAVYLIGLLTGITQGSFS--------LYPMVV 178
V+ + + + + + MG DI V L+ L+ + G + ++
Sbjct: 130 VSRILSEKTELGQPHGQMAMGVLLMQDIAVVPLMILIPALAGGGDGNIWAALGLAFAKML 189
Query: 179 LTIKIVVFIVATLLISEFVFKRSARFYNVV---KDLHVFFTFTIILTFMLAFLAEDIGLN 235
LT+ ++ F+ + ++ +R++ +V K +F +++T +A+L E GL+
Sbjct: 190 LTLGLLFFVGSKIM---------SRWFRMVAKRKSSELFMINVLLVTLGVAYLTELEGLS 240
Query: 236 QIIGAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGLMFQPNV 295
+GA++AG+ +S R ++ + I +LL F FFI VG+
Sbjct: 241 MALGAFVAGMLLSETE--------YRFQVEDDIRPFRDILLGF----FFITVGMKLDIQA 288
Query: 296 -----REISVLMIALLYLAAILGKLIGCGLGMLLFGSSLRDAIIVGVGMGGRGSLELAI 349
R++ +L+ LL L A++ I + + G SL+ A+ + G G G + LAI
Sbjct: 289 LIGGWRQVLMLLAMLLVLKALVVFAIAFKMKHSV-GDSLKTALYLAQG-GEFGFVMLAI 345
>pir||G70337 Na+/H+-exchanging protein - Aquifex aeolicus
>gi|2983090|gb|AAC06696.1| (AE000689) NA(+)/H(+)
antiporter [Aquifex aeolicus]
Length = 387
Score = 73.7 bits (178), Expect = 3e-12
Identities = 73/360 (20%), Positives = 160/360 (44%), Gaps = 28/360 (7%)
Query: 30 IAHILTGIILGPFGLAIVKPSEELKVLGEFGLIMMMLYMGLTSNFSAISRNKVKATIVAT 89
+ ++ GI++G F + I P E L L +FG +++M GL +F+ I + K V
Sbjct: 36 VGELIFGILIGNFFVGIQVP-EILNFLSDFGFLLLMFLAGLELDFNLIEKADKKQNAVYI 94
Query: 90 LGVAFSFILGFSTVYFIERNMIAALFVG-ITLGNTAIEVTSGVLVRERVKKEISSVLMGA 148
V F+ F + A+ + I+LG + ++ E K++ +L+G
Sbjct: 95 SYVLLIFLSAFVFGILLGIGTAPAIILSLISLGLMVATLKDMSVLEEPFAKKV--LLIGV 152
Query: 149 AFADDIIAVYLIGLLTGITQGSFSLYPMVVLTIKIVVFIVATLLISEFVFKRSARFYNVV 208
+II++ + L+ + F + ++ + ++ + + ++ + +Y +
Sbjct: 153 F--GEIISLLALTLMEKLLH--FHGFVSLIKELGVIFVFFFSFFLGFYLTRLLVWWYPEI 208
Query: 209 KDLHVF--------FTFTIILTFMLAFLAEDIGLNQIIGAYLAGLTISR-LRERKDPMVI 259
+ + ++ L F + A+ G+ ++GA++AG+ S +RE+KD
Sbjct: 209 VNRLTYEEDPSALGIRLSLFLMFTSSIFAKLAGIESVLGAFMAGVVFSYFIREKKD---- 264
Query: 260 TRIKLNELISELEVVLLEFFIPLFFIYVGLMFQPNVREISVLMIALLYLAAILGKLIGCG 319
L +L + F IP+FFI G+ + +++L ++LA +L +
Sbjct: 265 -------LEEKLSSIGYGFLIPIFFIKTGMGMEVAGLNLAILFKVFIFLAFMLFVRLIPS 317
Query: 320 LGMLLFGSSLRDAIIVGVGMGGRGSLELAILKLGLEKGLINESLFATIVIVSMLTALSTP 379
+LL G SL+D+ G+ + +L +A +++ G ++E + + + ++L P
Sbjct: 318 FVLLLAGFSLKDSFTAGLLLSYPFTLMVAGIEIARRGGALDEETALALFLTAAFSSLVFP 377
>sp|P03819|KEFC_ECOLI GLUTATHIONE-REGULATED POTASSIUM-EFFLUX SYSTEM PROTEIN KEFC
(K(+)/H(+) ANTIPORTER) >gi|2145008|pir||QQECRD
glutathione-regulated potassium efflux system protein
kefC [validated] - Escherichia coli
>gi|41875|emb|CAA40066.1| (X56742) KefC potassium efflux
system [Escherichia coli] >gi|216472|dbj|BAA01323.1|
(D10483) kefc potassium efflux system [Escherichia coli]
>gi|1786232|gb|AAC73158.1| (AE000115) K+ efflux
antiporter, glutathione-regulated [Escherichia coli K12]
Length = 620
Score = 73.4 bits (177), Expect = 4e-12
Identities = 71/301 (23%), Positives = 141/301 (46%), Gaps = 29/301 (9%)
Query: 25 GVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFGLIMMMLYMGLTSNFSAISRNKVKA 84
G+ ++ +++ G I+GP+GL +V +E + E G+++M+ +GL + + K++A
Sbjct: 27 GLGSVLGYLIAGCIIGPWGLRLVTDAESILHFAEIGVVLMLFIIGLELDPQRLW--KLRA 84
Query: 85 TIV---ATLGVAFSFILGFSTVYFIERNMIAALFVGITLGNTAIEVTSGVLVRERVKKEI 141
+ A V +LG + R +A L +G+TL + ++ + ++ ++ +
Sbjct: 85 AVFGCGALQMVICGGLLGLFCMLLGLRWQVAEL-IGMTLALS----STAIAMQAMNERNL 139
Query: 142 SSVLMG-AAFA----DDIIAVYLIGL--LTGITQGSFSLYPMVVLTIKIVVFIVATLLIS 194
MG +AFA DI A+ L+ + L + S ++ + +K+ +V +L+
Sbjct: 140 MVTQMGRSAFAVLLFQDIAAIPLVAMIPLLATSSASTTMGAFALSALKVAGALVLVVLLG 199
Query: 195 EFVFKRSARFYNVVKDLHVFFTFTIILTFMLAFLAEDIGLNQIIGAYLAGLTISRLRERK 254
+V + + RF VF + L F L E++GL+ +GA+LAG+ ++ R
Sbjct: 200 RYVTRPALRFVARSGLREVFSAVALFLVFGFGLLLEEVGLSMAMGAFLAGVLLASSEYR- 258
Query: 255 DPMVITRIKLNELISELEVVLLEFFIPLFFIYVGLMFQPNVREISVLMIALLYLAAILGK 314
+ L S++E + LFFI VG+ + L I +L L ++ K
Sbjct: 259 ----------HALESDIE-PFKGLLLGLFFIGVGMSIDFGTLLENPLRIVILLLGFLIIK 307
Query: 315 L 315
+
Sbjct: 308 I 308
>pir||G64578 glutathione-regulated potassium-efflux system protein -
Helicobacter pylori (strain 26695)
>gi|2313582|gb|AAD07539.1| (AE000562)
glutathione-regulated potassium-efflux system protein
(kefB) [Helicobacter pylori 26695]
Length = 416
Score = 72.2 bits (174), Expect = 1e-11
Identities = 77/340 (22%), Positives = 143/340 (41%), Gaps = 34/340 (10%)
Query: 21 LKKRGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFGLIMMMLYMGLTSNFSAISRN 80
LKK + II +I TG +L F + + L +GEFG++ +M +G+ NF +
Sbjct: 23 LKKLDMPVIIGYICTGTVLAAFFK--INDFDLLSDIGEFGIVFLMFMIGIEFNFDKLKSI 80
Query: 81 KVKATIVATLGVAFSFILGFSTVYFI---ERNMIAALFVGITLGNTAIEVTSGVLVRERV 137
K + + L V ++ F YF+ L +G++L +TAI VL
Sbjct: 81 KQEVLVFGLLQVVLCALIAFLLGYFVLGLSPIFSLVLGMGLSLSSTAI-----VLKFFED 135
Query: 138 KKEISSVL----MGAAFADDIIAVYLIGLLTGITQGSFSLYPMVVLTIKIVVFIVATLLI 193
K++S+ + +G DI A+ ++ +LT + ++ +++ T I+ LL+
Sbjct: 136 SKQLSTPMGKSAVGILIFQDIAAIPMLLILTILGSKDSNVNLLILKTFISAGIILVLLLL 195
Query: 194 SEFVFKRSAR-FYNVVKDL---HVFFTFTIILTFMLAFLAEDIGLNQIIGAYLAGLTISR 249
K+ A KD +F +++ A L+ G + +GA++ G+ IS+
Sbjct: 196 PG---KKGANLILEQAKDTRLPEIFIGTILVIVCSAAGLSHFFGFSMSLGAFIVGMAISK 252
Query: 250 LRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGLMFQPNVREISVLMIALLYLA 309
+R K+N + E L F+ LFFI +G+ + + + + L
Sbjct: 253 ----------SRYKIN--VQEEFAQLKNLFLALFFITIGMQINVSF-FMEKFFVVIFLLI 299
Query: 310 AILGKLIGCGLGMLLFGSSLRDAIIVGVGMGGRGSLELAI 349
++G +L F + AI + + G I
Sbjct: 300 LVMGFKTAIIYALLRFFRDAKTAIKTALSLAQIGEFSFVI 339
>pir||T00576 Na+/H+-exchanging protein homolog T27E13.2 - Arabidopsis thaliana
>gi|2347190|gb|AAC16929.1| (AC002338) putative Na+/H+
antiporter [Arabidopsis thaliana]
Length = 831
Score = 72.2 bits (174), Expect = 1e-11
Identities = 89/415 (21%), Positives = 184/415 (43%), Gaps = 54/415 (13%)
Query: 4 IFDLSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLA-------IVKPSEE---L 53
+ +S+++V ++ + +L+ I A +LTG++LGP L + P+ +
Sbjct: 56 LLQMSVIIVTSRLIFRVLQPLKQGMISAQVLTGVVLGPSFLGHNVIYMNMFLPAGGKIII 115
Query: 54 KVLGEFGLIMMMLYMGLTSNFSAISRNKVKATIVATLGVAFSFILGFSTVYFIERNM--- 110
+ L G ++ + +GL + S I + KA ++ T AF F LG T+ FI + M
Sbjct: 116 QTLSNVGFVIHLFLLGLKIDGSIIRKAGSKAILIGTASYAFPFSLGNLTIMFISKTMGLP 175
Query: 111 ---IAALFVGITLGN-TAIEVTSGVLVRERV-KKEISSVLMGAAFADDIIAVYLIGLLTG 165
I+ I+L + T+ VT+ VL + E+ + + ++ + + + L
Sbjct: 176 SDVISCTSSAISLSSMTSFPVTTTVLAELNILNSELGRLATHCSMVCEVCS-WFVALAFN 234
Query: 166 I-----TQGSFSLYPMVVLTIKIVVFIVATLLISEFVFKRSARFYNVVKDLHVFFTFTII 220
+ T S M++ + ++ F+ +++ ++ +R + + KD+ FF ++
Sbjct: 235 LYTRDRTMTSLYALSMIIGLLLVIYFVFRPIIV--WLTQRKTKSMD-KKDVVPFFPVLLL 291
Query: 221 LTFMLAFLAEDIGLNQIIGAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFI 280
L+ + + E +G++ GA+ G+++ P + T EL ++LE+ F+
Sbjct: 292 LS-IASLSGEAMGVHAAFGAFWLGVSLP-----DGPPLGT-----ELAAKLEMFASNLFL 340
Query: 281 PLFFIYVGLMFQPNVREIS------VLMIALLYLAAILGKLIGCGLGMLLFGSSLRDAII 334
P F GL Q N EI+ V+MI ++ L K +G + + DA+
Sbjct: 341 PCFIAISGL--QTNFFEITESHEHHVVMIEIILLITYGCKFLGTAAASAYCQTQIGDALC 398
Query: 335 VGVGMGGRGSLELAILKLGLEKGLINESLFATIVIVSMLTALSTPIFFRGVIRKL 389
+ M +G +E+ + + +++ F ++I T +F G+ R L
Sbjct: 399 LAFLMCCQGIIEVYTTIVWKDAQVVDTECFNLVII--------TILFVTGISRFL 445
>emb|CAB44437.1| (AJ242913) glutathione-gated K efflux system [Klebsiella aerogenes]
Length = 621
Score = 72.2 bits (174), Expect = 1e-11
Identities = 72/313 (23%), Positives = 149/313 (47%), Gaps = 34/313 (10%)
Query: 25 GVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFGLIMMMLYMGLTSNFSAISRNKVKA 84
G+ ++ +++ G I+GP+ L +V +E + E G+++M++ MGL + + K++A
Sbjct: 27 GLGSVLGYLIAGCIIGPWALRLVNDAEAILHFAEIGVVLMLVAMGLELDPQRLW--KLRA 84
Query: 85 TIV---ATLGVAFSFILGFSTVYFIERNMIAALFVGITLGNTAIEVTSGVLVRERVKKEI 141
++ A VA ++G + R +A L +G+TL + ++ + ++ ++ +
Sbjct: 85 SVFDGGALQMVACGVLIGLFCMLLGLRWQVAEL-IGMTLALS----STAIAMQAMNERNL 139
Query: 142 SSVLMG-AAFA----DDIIAVYLIGL--LTGITQGSFSLYPMVVLTIKIVVFIVATLLIS 194
+ MG +AFA DI A+ L+ + L + G+ SL + +K+ + +++
Sbjct: 140 TVSQMGRSAFAVLLFQDIAAIPLVAMIPLLAASGGATSLMAFALSALKVAAALALVVVLG 199
Query: 195 EFVFKRSARFYNVVKDLHVFFTFTIILTFMLAFLAEDIGLNQIIGAYLAGLTISRLRERK 254
++ + RF VF + L L E++GL+ +GA+LAG+ ++ R
Sbjct: 200 RYLTRPLLRFVARSGLREVFSAVACSWSSALGLLLEEVGLSMAMGAFLAGVLLASSEYR- 258
Query: 255 DPMVITRIKLNELISELEVVLLEFFIPLFFIYVGLM-----FQPNVREISVLMIALLYLA 309
+ L +++E V + LFFI VG+ + PN I +L++ +
Sbjct: 259 ----------HALENDIEPV-KGLLLGLFFIGVGMSIDFAPWSPNPLRIVILLVGFPAIK 307
Query: 310 AILGKLIGCGLGM 322
++ LI LG+
Sbjct: 308 MLMLWLIAQPLGV 320
>pir||F70591 probable kefB protein - Mycobacterium tuberculosis (strain H37RV)
>gi|2072703|emb|CAB08337.1| (Z95121) kefB [Mycobacterium
tuberculosis]
Length = 385
Score = 70.6 bits (170), Expect = 3e-11
Identities = 88/371 (23%), Positives = 159/371 (42%), Gaps = 57/371 (15%)
Query: 4 IFDLSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGE-FGLI 62
+F+L +LL V L + ++ + PI ++L G+ LG G+ V + E G G++
Sbjct: 8 LFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIATGAPIGVV 67
Query: 63 MMMLYMGL---TSNFSAISRNKVKATIV-----ATLGVAFSFILGFSTVYFIERNMIAAL 114
+++L +GL + F++ R+ + + V AT G ++LG V +
Sbjct: 68 LLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILG------- 120
Query: 115 FVGITLGNTAIEVTSGVL------VRERVKKEISSVLMGAAFADDIIAVYLIGLLTGITQ 168
G+T ++ SGV+ +R +E +VL D +A YL T
Sbjct: 121 LAGVTYISS-----SGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATD 175
Query: 169 GSFSLYPMVVLTIKIVVFIVATLLISEFVFKRSARFYNVV------KDLHVFFTFTIILT 222
GS+ L +V +T+ I + A F S R+ + V D + +T
Sbjct: 176 GSW-LEAVVGMTVAIAALLGA--------FAASYRWGHHVGRLVTHPDSEQLLLRVLGIT 226
Query: 223 FMLAFLAEDIGLNQIIGAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPL 282
++A +AE + + +GA+L GLT++ + MV+T ++ + F +
Sbjct: 227 LIVAAVAESLHASAAVGAFLVGLTLTGETADRARMVLTPLR-------------DLFATI 273
Query: 283 FFIYVGLMFQPNVREISVLMIALLYLAAILGKLIGCGL-GMLLFGSSLRDAIIVGVGMGG 341
FF+ +GL P + +S+L +AL A + G+ G + R + G +
Sbjct: 274 FFLGIGLSVDPG-KLVSMLPVALALAAVTAATKVATGMFAARREGVARRGQLRAGTALVA 332
Query: 342 RGSLELAILKL 352
RG L I+ L
Sbjct: 333 RGEFSLIIIGL 343
>pir||C71934 glutathione-regulated potassium-efflux system protein -
Helicobacter pylori (strain J99)
>gi|4154959|gb|AAD06004.1| (AE001476)
GLUTATHIONE-REGULATED POTASSIUM-EFFLUX SYSTEM PROTEIN
[Helicobacter pylori J99]
Length = 416
Score = 69.5 bits (167), Expect = 6e-11
Identities = 76/303 (25%), Positives = 133/303 (43%), Gaps = 35/303 (11%)
Query: 21 LKKRGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFGLIMMMLYMGLTSNFSAISRN 80
LKK + II +I TG +L F + L +GEFG++ +M +G+ NF +
Sbjct: 23 LKKLDMPVIIGYICTGTVLAAFFK--INDFNLLSDIGEFGIVFLMFMIGIEFNFDKLKSI 80
Query: 81 KVKATIVATLGVAFSFILGFSTVYFI---ERNMIAALFVGITLGNTAIEVTSGVLVRERV 137
K + + L V ++ F YF+ L +G++L +TAI VL
Sbjct: 81 KQEVLVFGLLQVVLCALIAFLLGYFVLGLSPIFSLVLGMGLSLSSTAI-----VLKFFED 135
Query: 138 KKEISSVL----MGAAFADDIIAVYLIGLLTGITQGSFSLYPMVVLTIKIVVFIVATLLI 193
K++S+ + +G DI A+ ++ +LT I S +++L I I+ LL+
Sbjct: 136 SKQLSTPMGKSAVGILIFQDIAAIPMLLILT-ILGSKDSHVNLLILKTLISAGIILILLL 194
Query: 194 SEFVFKRSAR-FYNVVKDL---HVFFTFTIILTFMLAFLAEDIGLNQIIGAYLAGLTISR 249
K+ A KD +F +++ A L+ G + +GA++ G+ IS+
Sbjct: 195 --LPGKKGANLILEQAKDTRLPEIFIGTVLVIVCSAAGLSHFFGFSMSLGAFIVGMAISK 252
Query: 250 LRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGLMFQPNVREISVLMIALLYLA 309
+R K+N + E L F+ LFFI +G+ Q NV +++L
Sbjct: 253 ----------SRYKIN--VQEEFAQLKNLFLALFFITIGM--QINVSFFMEKFFVVIFLL 298
Query: 310 AIL 312
++
Sbjct: 299 ILV 301
>pir||T01227 glutathione-regulated potassium-efflux system protein kefB homolog
F6N23.15 - Arabidopsis thaliana
>gi|3047127|gb|AAC13638.1| (AF058919) F6N23.15 gene
product [Arabidopsis thaliana]
>gi|7267402|emb|CAB80872.1| (AL161472) putative
potassium/H+ antiporter [Arabidopsis thaliana]
Length = 617
Score = 69.1 bits (166), Expect = 8e-11
Identities = 73/338 (21%), Positives = 146/338 (42%), Gaps = 24/338 (7%)
Query: 26 VHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFGLIMMMLYMGLTSNFSAISRNKVKAT 85
V P++ ++ GI++GP+GL+I++ K + EFG++ ++ +GL + +S K
Sbjct: 45 VTPVLGYLAAGILIGPYGLSIIRNVHGTKAIAEFGVVFLLFNIGLELSVERLSSMKKYVF 104
Query: 86 IVATLGV-AFSFILGFSTVYFIERNMIAALFVGITLGNTAIEVTSGVLVR-----ERVKK 139
+ + V + ++G T Y + AA+ +G L ++ V VL R +
Sbjct: 105 GLGSAQVLVTAAVIGLITHYVAGQAGPAAIVIGNGLALSSTAVVLQVLQERGESTSRHGR 164
Query: 140 EISSVLMGAAFADDIIAVYLIGLLTGITQGSFSLYPMV----VLTIKIVVFIVATLLISE 195
SVL+ A ++ + + + ++G + + IK V I +
Sbjct: 165 ATFSVLLFQDLAVVVLLILIPLISPNSSKGGIGFQAIAEALGLAAIKAAVAITGIIAGGR 224
Query: 196 FVFKRSARFYNVVKDLHVFFTFTIILTFMLAFLAEDIGLNQIIGAYLAGLTISRLRERKD 255
+ + + ++ +F T+++ + L GL+ +GA+LAGL ++
Sbjct: 225 LLLRPIYKQIAENRNAEIFSANTLLVILGTSLLTARAGLSMALGAFLAGLLLAETE---- 280
Query: 256 PMVITRIKLNELISELEVVLLEFFIPLFFIYVGLMFQPNVREISVLMIALLYLAAILGKL 315
+++ I+ +LL LFF+ VG+ P + + +I ++GK
Sbjct: 281 ----FSLQVESDIAPYRGLLL----GLFFMTVGMSIDPKLLLANFPLIMGTLGLLLVGKT 332
Query: 316 IGCGLGMLLFGSSLRDAIIVGVGMGGRGSLELAILKLG 353
I + LFG S+ A+ VG+ + G E A + G
Sbjct: 333 ILVVIIGKLFGISIISAVRVGLLLAPGG--EFAFVAFG 368
>gb|AAA84962.1| (U37008) KefC [Myxococcus xanthus]
Length = 598
Score = 69.1 bits (166), Expect = 8e-11
Identities = 79/377 (20%), Positives = 159/377 (41%), Gaps = 24/377 (6%)
Query: 1 MNYIFDLSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFG 60
M+++ + L + L ++ G+ ++ ++ G ++GP+GL ++ E + + E G
Sbjct: 1 MSFLQQALVFLAAVVLADPLSRRLGLGSVLGYLAGGAVIGPWGLKLISDVEHIFHVAELG 60
Query: 61 LIMMMLYMGLTSNFSAISRNKVKATIVATLGVAFSFILGFSTVYFIERNMIAALFVGITL 120
+++++L++ L S + + + V F+ L S AA+ G L
Sbjct: 61 VVVLLLFVSLELQTSRLWALRRSVFGLGGAQVLFTGALLASVGLLCSLTWGAAIVTGFGL 120
Query: 121 GNTAIEVTSGVLV-RERVKKEISSVLMGAAFADDIIAVYLIGLLTGITQGSF-SLYPMVV 178
++ +LV R R+ + G D+ V L+ LL + G S + +
Sbjct: 121 SLSSTAFALQLLVERNRLTTPYGQLAFGILLFQDLAVVPLLALLPLLGDGGAPSPGTVWL 180
Query: 179 LTIKIVVFIVATLLISEFVFKRSARFYNVVKDLHVFFTFTIILTFMLAFLAEDIGLNQII 238
L +K V ++A +L ++ + + R +F ++L A + +GL+ +
Sbjct: 181 LLLKDVGVLLAEVLSGRYLVRPAFRAVAATHRQELFTATALLLVVATASVINAVGLSMGL 240
Query: 239 GAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEF---FIPLFFIYVGLMFQPNV 295
A LAG+ ++ +E ELE L F + LFFI VG+ ++
Sbjct: 241 AASLAGVLLAD---------------SEYRHELEADLAPFKGLLMGLFFISVGMTVNLSL 285
Query: 296 REISVLMI--ALLYLAAILGKLIGCGLGMLLFGSSLRDAIIVGVGMGGRGSLELAILKLG 353
L++ +L L A+ G ++ GLG + G A+ + V + G + L
Sbjct: 286 ILQKPLLVFGLVLGLVALKGAVL-YGLGRMALGRR-EPALDLAVVISQGGEFAFVLFSLA 343
Query: 354 LEKGLINESLFATIVIV 370
+ ++ SL +V+V
Sbjct: 344 TAQHVMERSLSELLVVV 360
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.331 0.148 0.408
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 119266967
Number of Sequences: 2977
Number of extensions: 4719968
Number of successful extensions: 18858
Number of sequences better than 1.0e-10: 64
Number of HSP's better than 0.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 58
Number of HSP's that attempted gapping in prelim test: 18671
Number of HSP's gapped (non-prelim): 70
length of query: 390
length of database: 189,106,746
effective HSP length: 55
effective length of query: 335
effective length of database: 156,189,961
effective search space: 52323636935
effective search space used: 52323636935
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (21.9 bits)
S2: 166 (69.1 bits)