BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0818 (manC) DE:mannose-6-phosphate
isomerase/mannose-1-phosphate guanylyl transferase (manC)
(465 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||G75104 mannose-6-phosphate isomerase/mannose-1- phosphate g... 942 0.0
pir||G71082 probable mannose-1-phosphate guanylyl transferase - ... 894 0.0
gi|11498697 mannose-6-phosphate isomerase/mannose-1-phosphate gu... 602 e-171
gb|AAC61851.1| (AF053937) phosphomannose isomerase/GDP-mannose p... 400 e-110
pir||H70352 mannose-6-phosphate isomerase/mannose-1-phosphate gu... 399 e-110
pir||A83367 probable phosphomannose isomerase/GDP-mannose pyroph... 399 e-110
sp|P29956|XANB_XANCP XANTHAN BIOSYNTHESIS PROTEIN XANB [INCLUDES... 398 e-110
pir||F82964 phosphomannose isomerase/GDP-mannose WbpW PA5452 [im... 397 e-109
pir||T44446 D-rhamnose synthesis protein wbpW [imported] - Pseud... 393 e-108
gb|AAC60775.1| (U46859) ManC [Yersinia enterocolitica (type 0:8)... 379 e-104
sp|Q01410|MANC_SALMO MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE (GD... 378 e-104
emb|CAA57100.1| (X81320) phosphomannose isomerase and GDP-mannos... 378 e-104
pir||T44334 hypothetical protein manC [imported] - Vibrio choler... 377 e-103
pir||F82828 phosphomannose isomerase-GDP-mannose pyrophosphoryla... 377 e-103
pir||S70879 GDP-mannose pyrophosphorylase rfbM homolog - Vibrio ... 375 e-103
dbj|BAB03201.1| (AB046360) putative GOP-mannose phosphorylase [A... 374 e-102
pir||E47677 guanosine diphosphomannose pyrophosphorylase, GDP-ma... 374 e-102
emb|CAB63302.1| (AJ251712) mannose-1-P guanylyltransferase [Yers... 371 e-101
emb|CAB63283.1| (AJ251713) mannose-1-P guanylyltransferase [Yers... 371 e-101
pir||B83201 phosphomannose isomerase / guanosine 5'-diphospho-D-... 370 e-101
sp|Q48462|MANC_KLEPN MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE (GD... 369 e-101
emb|CAA69110.1| (Y07786) guanylyl transferase [Vibrio cholerae] 368 e-101
pir||H64970 mannose-1-phosphate guanylyltransferase (GDP) (EC 2.... 367 e-100
pir||H82345 mannose-1-phosphate guanylyltransferase VC0241 [impo... 367 e-100
pir||I57096 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13... 367 e-100
sp|P07874|ALGA_PSEAE ALGINATE BIOSYNTHESIS PROTEIN ALGA [INCLUDE... 366 e-100
sp|P24174|MANC_ECOLI MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE (GD... 366 e-100
pir||A25638 mannose-6-phosphate isomerase (EC 5.3.1.8) - Pseudom... 365 e-100
sp|P37753|RFM9_ECOLI MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE (GD... 363 2e-99
pir||I41251 GDP-mannose pyrophosphorylase [validated] - Escheric... 363 3e-99
dbj|BAA28322.1| (AB010150) GDP-mannose pyrophosphorylase [Escher... 363 3e-99
sp|P55357|NOEJ_RHISN MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE (GD... 361 7e-99
sp|P26340|MANC_SALTY MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE (GD... 360 2e-98
gb|AAC32348.1| (AF061251) mannose-1-P guanosyltransferase ManC [... 359 3e-98
dbj|BAA77733.1| (AB008676) mannose-1-phoshate guanylyltransferas... 358 1e-97
dbj|BAA02175.1| (D12652) pssM protein [Rhodospirillum rubrum] 351 1e-95
pir||S30187 mannose-6-phosphate isomerase (EC 5.3.1.8) / mannose... 351 1e-95
sp|Q00473|RFBM_SALMU MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE (GD... 349 4e-95
gb|AAC44882.1| (AF078736) mannose-1-phosphate guanylyltransferas... 348 9e-95
gb|AAF04378.1|AF189151_1 (AF189151) ManC; GDP-mannose pyrophosph... 346 3e-94
prf||2123305B rfbM gene [Escherichia coli] 345 6e-94
dbj|BAA28337.1| (AB010295) GDP-mannose pyrophosphorylase [Klebsi... 344 1e-93
pir||C71981 phosphomannose isomerase/gdp-mannose pyrophosphoryla... 344 2e-93
dbj|BAA28333.1| (AB010294) GDP-mannose pyrophosphorylase [Escher... 341 8e-93
sp|P26404|RFBM_SALTY MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE (GD... 341 1e-92
dbj|BAA28329.1| (AB010293) GDP-mannose pyrophosphorylase [Escher... 340 2e-92
pir||C64525 mannose-6-phosphate isomerase - Helicobacter pylori ... 339 6e-92
sp|Q07024|RFBA_VIBCH PUTATIVE MANNOSE-1-PHOSPHATE GUANYLYLTRANSF... 332 6e-90
gb|AAC27538.1| (AF125322) ManC [Escherichia coli] 331 1e-89
emb|CAA72316.1| (Y11554) mannose-6-phosphate isomerase [Acetobac... 330 3e-89
gb|AAC46167.1| (AF017434) pmi-like gene product [Methylobacteriu... 303 3e-81
sp|P37741|RFM7_ECOLI MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE (GD... 269 5e-71
pir||H72303 mannose-1-phosphate guanylyltransferase - Thermotoga... 255 9e-67
dbj|BAA94400.1| (AB041266) GDP-mannose pyrophosphorylase homolog... 254 1e-66
pir||S75700 GDP-mannose pyrophosphorylase - Synechocystis sp. (s... 213 2e-54
pir||B75596 mannose-1-phosphate guanylyltransferase - Deinococcu... 203 4e-51
gb|AAA02893.1| (M77127) phosphomanose isomerase [Escherichia coli] 166 4e-40
gb|AAC80269.1| (AF031957) GDP-mannose pyrophosphorylase [Shigell... 162 7e-39
pir||S74405 mannose-6-phosphate isomerase (EC 5.3.1.8) rfbM - Sy... 159 8e-38
dbj|BAA08633.1| (D49826) unnamed protein product [Serratia marce... 154 2e-36
pir||S77561 mannose-6-phosphate isomerase (EC 5.3.1.8) manA - Sy... 136 4e-31
pir||S04426 hypothetical protein - Synechococcus sp >gi|1405429|... 130 4e-29
emb|CAA67491.1| (X99019) AlgA protein [Azotobacter vinelandii] 127 3e-28
gb|AAG20296.1| (AE005104) mannose-1-phosphate guanylyltransferas... 125 1e-27
emb|CAA10658.1| (AJ132366) mannose 6 phosphate isomerase [Helico... 78 3e-13
>pir||G75104 mannose-6-phosphate isomerase/mannose-1- phosphate guanylyl
transferase (manc) PAB0818 - Pyrococcus abyssi (strain
Orsay) >gi|5458652|emb|CAB50140.1| (AJ248286)
mannose-6-phosphate isomerase/mannose-1-phosphate
guanylyl transferase (manC) [Pyrococcus abyssi]
Length = 465
Score = 942 bits (2407), Expect = 0.0
Identities = 465/465 (100%), Positives = 465/465 (100%)
Query: 1 MKTLILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERALLFSKPKEIFIVTNKEY 60
MKTLILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERALLFSKPKEIFIVTNKEY
Sbjct: 1 MKTLILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERALLFSKPKEIFIVTNKEY 60
Query: 61 KFRVLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENYGDSVVAVLPSDHAIKV 120
KFRVLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENYGDSVVAVLPSDHAIKV
Sbjct: 61 KFRVLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENYGDSVVAVLPSDHAIKV 120
Query: 121 NDNYMEAFKKAEKLAEKYLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKEKP 180
NDNYMEAFKKAEKLAEKYLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKEKP
Sbjct: 121 NDNYMEAFKKAEKLAEKYLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKEKP 180
Query: 181 DLETAKKYVENGYYWNSGMFMFRTSVFMEEARKHAPETVRAFEEGKSIEEIYELVPEISV 240
DLETAKKYVENGYYWNSGMFMFRTSVFMEEARKHAPETVRAFEEGKSIEEIYELVPEISV
Sbjct: 181 DLETAKKYVENGYYWNSGMFMFRTSVFMEEARKHAPETVRAFEEGKSIEEIYELVPEISV 240
Query: 241 DYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAGFKAKYININSRNNL 300
DYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAGFKAKYININSRNNL
Sbjct: 241 DYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAGFKAKYININSRNNL 300
Query: 301 ILTERLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLREENDERAIVHRTAYRPW 360
ILTERLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLREENDERAIVHRTAYRPW
Sbjct: 301 ILTERLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLREENDERAIVHRTAYRPW 360
Query: 361 GSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAKVVVGDKEFILRPGES 420
GSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAKVVVGDKEFILRPGES
Sbjct: 361 GSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAKVVVGDKEFILRPGES 420
Query: 421 TFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFGRE 465
TFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFGRE
Sbjct: 421 TFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFGRE 465
>pir||G71082 probable mannose-1-phosphate guanylyl transferase - Pyrococcus
horikoshii >gi|3257338|dbj|BAA30021.1| (AP000004) 464aa
long hypothetical mannose-1-phosphate guanylyl
transferase [Pyrococcus horikoshii]
Length = 464
Score = 894 bits (2285), Expect = 0.0
Identities = 429/464 (92%), Positives = 456/464 (97%)
Query: 1 MKTLILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERALLFSKPKEIFIVTNKEY 60
MK LILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERAL+FSKPKEIF+VTNKEY
Sbjct: 1 MKALILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERALIFSKPKEIFVVTNKEY 60
Query: 61 KFRVLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENYGDSVVAVLPSDHAIKV 120
+FRVLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVI++NYGDSVVAVLPSDHAI+V
Sbjct: 61 RFRVLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVINDNYGDSVVAVLPSDHAIEV 120
Query: 121 NDNYMEAFKKAEKLAEKYLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKEKP 180
N++YMEAFKKAEKLAEKYLVTFGIKPTKPHTGYGYIKPGEKI+VEGK +GYLVDEFKEKP
Sbjct: 121 NESYMEAFKKAEKLAEKYLVTFGIKPTKPHTGYGYIKPGEKIEVEGKVLGYLVDEFKEKP 180
Query: 181 DLETAKKYVENGYYWNSGMFMFRTSVFMEEARKHAPETVRAFEEGKSIEEIYELVPEISV 240
DLETA+KYVENGYYWNSGMFMF+ SVFMEEARKH+P+ V+AFEEGKSIEEIYEL PEISV
Sbjct: 181 DLETARKYVENGYYWNSGMFMFKVSVFMEEARKHSPDVVKAFEEGKSIEEIYELAPEISV 240
Query: 241 DYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAGFKAKYININSRNNL 300
DYGIMEKT+KAAVVPLNTYWNDLGSFDAVYEAL+KDENGNAV V GFKAKYIN++SRNNL
Sbjct: 241 DYGIMEKTNKAAVVPLNTYWNDLGSFDAVYEALEKDENGNAVHVTGFKAKYINVDSRNNL 300
Query: 301 ILTERLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLREENDERAIVHRTAYRPW 360
+LTERLTATVGVEDL+I+DTGDALLVAKRGETQKVKEVYK+L+EENDERAIVHRTAYRPW
Sbjct: 301 VLTERLTATVGVEDLVIIDTGDALLVAKRGETQKVKEVYKKLKEENDERAIVHRTAYRPW 360
Query: 361 GSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAKVVVGDKEFILRPGES 420
GSYTVLEEGERYKIKR+TVLPGKRLSLQIHYHRSEHWVVVRGTAKV VGDKEFILRPGES
Sbjct: 361 GSYTVLEEGERYKIKRLTVLPGKRLSLQIHYHRSEHWVVVRGTAKVKVGDKEFILRPGES 420
Query: 421 TFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFGR 464
TFIPAGVPHRLENPGKV+LEVIETQIGEYLGEDDIVRLQDD+GR
Sbjct: 421 TFIPAGVPHRLENPGKVILEVIETQIGEYLGEDDIVRLQDDYGR 464
>gi|11498697 mannose-6-phosphate isomerase/mannose-1-phosphate guanylyl
transferase (manC) [Archaeoglobus fulgidus]
>gi|7428438|pir||H69386 mannose-6-phosphate
isomerase/mannose-1-phosphate guanylyl transferase
(manC) homolog - Archaeoglobus fulgidus
>gi|2649495|gb|AAB90149.1| (AE001028)
mannose-6-phosphate isomerase/mannose-1-phosphate
guanylyl transferase (manC) [Archaeoglobus fulgidus]
Length = 448
Score = 602 bits (1535), Expect = e-171
Identities = 291/464 (62%), Positives = 366/464 (78%), Gaps = 17/464 (3%)
Query: 1 MKTLILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERALLFSKPKEIFIVTNKEY 60
MKTLILAGGKGTRLWPLSRE MPKQFIK+FS+ SLFQKTV+RAL S P EI+++TNKEY
Sbjct: 1 MKTLILAGGKGTRLWPLSRELMPKQFIKLFSE-SLFQKTVKRALYLSSPDEIYVITNKEY 59
Query: 61 KFRVLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENYGDSVVAVLPSDHAIKV 120
+FRVLDDL E+G+ +PEENI+LEP KNTLPAI G+K G+ AVLPSDH IK
Sbjct: 60 RFRVLDDLEEIGISIPEENIILEPEAKNTLPAICLGVKAA----GEGKFAVLPSDHLIKA 115
Query: 121 NDNYMEAFKKAEKLAEKYLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKEKP 180
++ Y+ AF+ AEKL+E Y+VTFGI PT+PHTGYGYIKPG+++ EG G+ V++FKEKP
Sbjct: 116 DEEYLNAFRSAEKLSENYIVTFGITPTRPHTGYGYIKPGKEL--EG---GFEVEQFKEKP 170
Query: 181 DLETAKKYVENGYYWNSGMFMFRTSVFMEEARKHAPETVRAFEEGKSIEEIYELVPEISV 240
E A++YV GY WNSGMF+F + VF+EE ++ APE + EEG EE Y+ +PE S
Sbjct: 171 SRELAEEYVSKGYLWNSGMFVFDSKVFVEELKELAPEFAKVLEEG---EEAYKQIPEASF 227
Query: 241 DYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAGFKAKYININSRNNL 300
DY I+EK+ + AVVP+ T+W+DLG+FD++YE ++KDE GNA++ I ++S NNL
Sbjct: 228 DYAILEKSGRVAVVPIKTFWSDLGNFDSIYEVMEKDERGNAIK----SESCIPVDSENNL 283
Query: 301 ILTERLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLREENDERAIVHRTAYRPW 360
++T+RLTA +G+ DLI++DT DALLVA+RGE +KV+EVY+ L E+ D+ VHRTA+RPW
Sbjct: 284 VITQRLTALIGLRDLIVIDTDDALLVARRGEAEKVREVYRLLAEKGDKAVEVHRTAHRPW 343
Query: 361 GSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAKVVVGDKEFILRPGES 420
GSYTVLEE + YKIKRITV P KRLSLQ HYHRSEHWVVV+GTA++VV E +LR GES
Sbjct: 344 GSYTVLEENKSYKIKRITVKPKKRLSLQRHYHRSEHWVVVKGTARIVVDGNEILLRSGES 403
Query: 421 TFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFGR 464
TF+PAG HR+ENPGK+ LE+IE QIGEYL EDDI R +DDFGR
Sbjct: 404 TFVPAGAIHRIENPGKIPLEIIEIQIGEYLEEDDIERFEDDFGR 447
>gb|AAC61851.1| (AF053937) phosphomannose isomerase/GDP-mannose pyrophosphorylase
homolog [Pseudomonas aeruginosa]
Length = 488
Score = 400 bits (1017), Expect = e-110
Identities = 221/478 (46%), Positives = 296/478 (61%), Gaps = 27/478 (5%)
Query: 5 ILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERALLFSKPKEIFIVTNKEYKFRV 64
I++GG GTRLWP+SRE+MPK F+++ D+SL QKT R + VTN++ FR
Sbjct: 11 IVSGGSGTRLWPVSRESMPKPFMRLADDQSLLQKTFLRIAGLPDVARLLTVTNRDLLFRT 70
Query: 65 LDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENYGDSV-VAVLPSDHAIKVNDN 123
LDD + +++LLEPVG+NT PAI + E++GD + +LP+DH I+
Sbjct: 71 LDDYRAVNRSGLAQDLLLEPVGRNTAPAIAAAALHVQEHFGDQAQLLILPADHLIRDEQA 130
Query: 124 YMEAFKKAEKLAEK-YLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKEKPDL 182
+ A +A LA + YLVTFGI P + TG+GYI+ G + G+ V F EKPD
Sbjct: 131 FAAAVAEARGLAAQGYLVTFGITPERAETGFGYIEQGAPLGN-----GFRVARFVEKPDQ 185
Query: 183 ETAKKYVENG-YYWNSGMFMFRTSVFMEEARKHAPETV----RAFEEGKSIEE------- 230
TA+ Y+++G Y WN+GMF F+ + ++E +HAPE + A +G S+E
Sbjct: 186 ATAQSYLDSGKYLWNAGMFCFQAATVLQELERHAPEVLIAARAALADGSSLENGQCRQRE 245
Query: 231 ----IYELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAG 286
+ P+ISVDY +ME++DK AVVP + W+D+GS+ A+ E DENGN QV G
Sbjct: 246 LAAGAFPQAPDISVDYALMERSDKVAVVPCSIGWSDIGSWQALRELSAADENGN--QVRG 303
Query: 287 FKAKYININSRNNLILTERLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLREEN 346
++ S + +RL VGV DLIIVDT DALLVA +Q VK V + L+
Sbjct: 304 --ESVLHDVSNCYIDSPKRLVGAVGVHDLIIVDTPDALLVADAARSQDVKFVAQELKRRG 361
Query: 347 DERAIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAKV 406
+ +HRT RPWG+YTVLEEG R+KIKRI V P + LSLQ+H+HRSEHW+VV G A V
Sbjct: 362 HDAFRLHRTVSRPWGTYTVLEEGRRFKIKRIVVRPKRSLSLQMHHHRSEHWIVVSGMALV 421
Query: 407 VVGDKEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFGR 464
G++EF+L ESTFIPAG HRL NPG + L +IE Q GEYLGEDDIVR D +GR
Sbjct: 422 ENGEREFLLNTNESTFIPAGHSHRLSNPGIIDLVMIEVQSGEYLGEDDIVRFNDIYGR 479
>pir||H70352 mannose-6-phosphate isomerase/mannose-1-phosphate guanyl
transferase - Aquifex aeolicus
>gi|2983213|gb|AAC06811.1| (AE000697)
mannose-6-phosphate isomerase/mannose-1-phosphate guanyl
transferase [Aquifex aeolicus]
Length = 453
Score = 399 bits (1013), Expect = e-110
Identities = 215/465 (46%), Positives = 312/465 (66%), Gaps = 18/465 (3%)
Query: 1 MKTLILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERALLFSKPKEIFIVTNKEY 60
MK LIL+GGKGTRLWPLSRE PKQFI++FS SLFQ+TV+RA +K ++I ++T ++Y
Sbjct: 1 MKILILSGGKGTRLWPLSRENFPKQFIRLFSKHSLFQETVKRAKKLAKDEDIVVITGEKY 60
Query: 61 KFRVLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVI--DENYGDSVVAVLPSDHAI 118
++ + +L E+ E +++EP G+NT PAI G+K + E V VLPSDH I
Sbjct: 61 EWIIRSELEEIDAN--EVRVVVEPEGRNTAPAIALGVKYLIHSETPPSETVLVLPSDHLI 118
Query: 119 KVNDNYMEAFKKAEKLA-EKYLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFK 177
K + ++EA KK EK A E Y+V FG KPT P TGYGYI+ K++ EG Y +++F+
Sbjct: 119 KDTEKFVEAVKKGEKYAKEGYIVLFGEKPTYPETGYGYIRLNGKLE-EGV---YEIEKFE 174
Query: 178 EKPDLETAKKYVENG-YYWNSGMFMFRTSVFMEEARKHAPETVRAFEEGKSIEEIYELVP 236
EKPD E AK+YV +G ++WN G+F+F +++ + PE + E+ + + ++
Sbjct: 175 EKPDYEKAKEYVSDGKHFWNCGIFLFTLDRIVKDYTQLMPE-IPFHEKWEDFIKDFKNFE 233
Query: 237 EISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAGFKAKYININS 296
EIS DY I+E+T K AVV ++ W+D+GS+ AVY+ L KDE N V + KA +++
Sbjct: 234 EISFDYAILERTKKLAVVKMDAGWSDVGSWKAVYDNLPKDEKRN-VLIGDVKA----MDT 288
Query: 297 RNNLILTE--RLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLREENDERAIVHR 354
+L+L++ L A +G+ED ++V T DA L+ KR +QKVKE+ K L EENDERAI H
Sbjct: 289 ECSLLLSQGKNLIACIGLEDFVVVGTEDATLIVKRDYSQKVKEIVKELEEENDERAIEHV 348
Query: 355 TAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAKVVVGDKEFI 414
T++ P+GS T L+ GERYKI+++ V K + L++H+HR+ H+VV++GTAKV VGDKE
Sbjct: 349 TSFTPFGSITKLDRGERYKIRKVVVKKDKEIPLRMHHHRTVHFVVLKGTAKVKVGDKEEF 408
Query: 415 LRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQ 459
+ ES F+P P+++ N GK+ LE+IE Q GEYLGEDD+ L+
Sbjct: 409 VHENESFFVPKSTPYKIINVGKIPLEMIEVQSGEYLGEDDVETLE 453
>pir||A83367 probable phosphomannose isomerase/GDP-mannose pyrophosphorylase
PA2232 [imported] - Pseudomonas aeruginosa (strain PAO1)
>gi|9948257|gb|AAG05620.1|AE004649_11 (AE004649)
probable phosphomannose isomerase/GDP-mannose
pyrophosphorylase [Pseudomonas aeruginosa]
Length = 488
Score = 399 bits (1013), Expect = e-110
Identities = 221/478 (46%), Positives = 295/478 (61%), Gaps = 27/478 (5%)
Query: 5 ILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERALLFSKPKEIFIVTNKEYKFRV 64
I++GG GTRLWP+SRE+MPK F+++ D+SL QKT R + VTN++ FR
Sbjct: 11 IVSGGSGTRLWPVSRESMPKPFMRLADDQSLLQKTFLRIAGLPDVARLLTVTNRDLLFRT 70
Query: 65 LDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENYGDSV-VAVLPSDHAIKVNDN 123
LDD + +++LLEPVG+NT PAI + E++GD + +LP+DH I+
Sbjct: 71 LDDYRAVNRSGLAQDLLLEPVGRNTAPAIAAAALHVQEHFGDQAQLLILPADHLIRDEQA 130
Query: 124 YMEAFKKAEKLAEK-YLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKEKPDL 182
+ A +A LA + YLVTFGI P + TG+GYI+ G + G+ V F EKPD
Sbjct: 131 FAAAVAEARGLAAQGYLVTFGITPERAETGFGYIEQGAPLGN-----GFRVARFVEKPDQ 185
Query: 183 ETAKKYVENG-YYWNSGMFMFRTSVFMEEARKHAPETV----RAFEEGKSIEE------- 230
TA+ Y+++G Y WN+GMF F+ + ++E +HAPE + A +G S+E
Sbjct: 186 ATAQSYLDSGKYLWNAGMFCFQAATVLQELERHAPEVLIAARAALADGSSLENGQCRQRE 245
Query: 231 ----IYELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAG 286
+ P+ISVDY +ME++DK AVVP + W+D+GS+ A+ E DENGN QV G
Sbjct: 246 LAAGAFAEAPDISVDYALMERSDKVAVVPCSIGWSDIGSWQALRELSAADENGN--QVRG 303
Query: 287 FKAKYININSRNNLILTERLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLREEN 346
++ S + +RL VGV DLIIVDT DALLVA +Q VK V + L+
Sbjct: 304 --ESVLHDVSNCYIDSPKRLVGAVGVHDLIIVDTPDALLVADAARSQDVKFVAQELKRRG 361
Query: 347 DERAIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAKV 406
+ +HRT RPWG+YTVLEEG R+KIKRI V P LSLQ+H+HRSEHW+VV G A V
Sbjct: 362 HDAFRLHRTVSRPWGTYTVLEEGRRFKIKRIVVRPKASLSLQMHHHRSEHWIVVSGMALV 421
Query: 407 VVGDKEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFGR 464
G++EF+L ESTFIPAG HRL NPG + L +IE Q GEYLGEDDIVR D +GR
Sbjct: 422 ENGEREFLLNTNESTFIPAGHSHRLSNPGIIDLVMIEVQSGEYLGEDDIVRFNDIYGR 479
>sp|P29956|XANB_XANCP XANTHAN BIOSYNTHESIS PROTEIN XANB [INCLUDES: MANNOSE-6-PHOSPHATE
ISOMERASE (PHOSPHOMANNOSE ISOMERASE) (PMI)
(PHOSPHOHEXOMUTASE); MANNOSE-1-PHOSPHATE GUANYLYL
TRANSFERASE (GDP) (GDP-MANNOSE PYROPHOSPHORYLASE) (GMP)]
>gi|281624|pir||B43304 phosphomannose
isomerase-GDP-mannose pyrophosphorylase - Xanthomonas
campestris >gi|155396|gb|AAA27611.1| (M83231) Encodes
phosphomannose isomerase and GDP-mannose
pyrophosphorylase [Xanthomonas campestris]
Length = 466
Score = 398 bits (1012), Expect = e-110
Identities = 216/474 (45%), Positives = 292/474 (61%), Gaps = 28/474 (5%)
Query: 4 LILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERALLFSKPKEIFIVTNKEYKFR 63
+IL+GG GTRLWPLSRE PKQF+ + + S+ Q T R+ + I +V N+E++F
Sbjct: 7 IILSGGSGTRLWPLSRETYPKQFLPLVGEHSMLQATWLRSAPVAAHAPI-VVANEEHRFM 65
Query: 64 VLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENYGDSVVAVLPSDHAIKVNDN 123
+ L +LG+K ILLEP G+NT PAI N GD ++ VLPSDH I+
Sbjct: 66 AAEQLQQLGVK--PSAILLEPKGRNTAPAIAVAALEATRNGGDPLLLVLPSDHVIRDEAA 123
Query: 124 YMEAFKKAEKLAEK-YLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKEKPDL 182
+ A A AE+ LVTFGIKPT P TGYGYIK G V+ F EKPDL
Sbjct: 124 FQAAVTVAAAAAEQGKLVTFGIKPTAPETGYGYIKAGAGTATA-------VERFVEKPDL 176
Query: 183 ETAKKYVENG-YYWNSGMFMFRTSVFMEEARKHAPETV----RAFEEGKSIEEIYEL--- 234
TA+ Y+ +G YYWNSGMF+FR S ++EE RK P +A+E GK + L
Sbjct: 177 ATAQGYLASGEYYWNSGMFLFRASRYLEELRKFQPAIADACQKAWEGGKRDADFTRLDKD 236
Query: 235 ----VPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAGFKAK 290
P S+DY +MEKT A VVPL+ WND+GS+ ++ + ++D GNA
Sbjct: 237 AFASSPSDSIDYAVMEKTADAVVVPLDAGWNDVGSWSSLLDVSEQDGQGNA-----HHGD 291
Query: 291 YININSRNNLILTERLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLREENDERA 350
I ++ +N RL A VG+E++++V+T DA+LV R Q+VKEV +++ A
Sbjct: 292 VIQLDCKNTYAYGSRLIAMVGLENVVVVETDDAVLVGHRDRIQEVKEVVSQIKSAGRSEA 351
Query: 351 IVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAKVVVGD 410
HR YRPWG+Y ++ G+R+++KRITV PG LSLQ+H+HR+EHW+VV GTA+V GD
Sbjct: 352 TWHRKVYRPWGAYDSIDMGQRFQVKRITVKPGATLSLQMHHHRAEHWIVVSGTAEVTRGD 411
Query: 411 KEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFGR 464
+ +L +ST+IP GV HRL+NPGK+ LE+IE Q G YLGEDDIVR +D +GR
Sbjct: 412 EVLLLTENQSTYIPLGVTHRLKNPGKLPLELIEVQSGSYLGEDDIVRFEDTYGR 465
>pir||F82964 phosphomannose isomerase/GDP-mannose WbpW PA5452 [imported] -
Pseudomonas aeruginosa (strain PAO1)
>gi|9951783|gb|AAG08837.1|AE004958_7 (AE004958)
phosphomannose isomerase/GDP-mannose WbpW [Pseudomonas
aeruginosa]
Length = 479
Score = 397 bits (1009), Expect = e-109
Identities = 218/481 (45%), Positives = 305/481 (63%), Gaps = 28/481 (5%)
Query: 4 LILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERAL-LFSKPKEIFIVTNKEYKF 62
++L+GG GTRLWP+SRE PK F+++ ++L KT RA L + EI VTN+E+ F
Sbjct: 5 VVLSGGAGTRLWPVSREGQPKPFMRLPDGQTLLGKTYRRAAGLLAGHGEIVTVTNREHYF 64
Query: 63 RVLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENYGDS-VVAVLPSDHAIKVN 121
+ D + L + +LEP G+NT PAI + +GD+ V+ V+P+DH I+
Sbjct: 65 QSKDQFHAARLGRHRGHFILEPTGRNTAPAIAVAALALQAEHGDAAVLVVMPADHLIRNE 124
Query: 122 DNYMEAFKKAEKLAEK-YLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKEKP 180
+ + EA A +LA +LVTFG+ P TG+GYI+ G+++ +G V F EKP
Sbjct: 125 EAFREAVGHAARLAVAGHLVTFGVVPDAAETGFGYIELGDRLDEQGAA---KVRRFVEKP 181
Query: 181 DLETAKKYVENG-YYWNSGMFMFRTSVFMEEARKHAP---ETVRA---------FEEGKS 227
D ETA++YVE+G + WNSGMF F S ++E +HAP E RA +G
Sbjct: 182 DEETARRYVESGGFLWNSGMFCFTASTLVDELAQHAPALLEQARACLAASAAVKMADGIQ 241
Query: 228 IE---EIYELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQV 284
E E + +P+IS+DY +ME++ + AVVP W+D+GS+ A+ LD D GN
Sbjct: 242 HELAGEAFAALPDISIDYALMERSARVAVVPAAFDWSDIGSWGAMSALLDADAEGNRGS- 300
Query: 285 AGFKAKYININSRNNLILTE-RLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLR 343
+ +++RN + ++ RL ATVGV+DL++VDT DALL+A+ Q+V+ V +RL+
Sbjct: 301 ----GDTLFVDTRNTFVQSDGRLVATVGVDDLVVVDTSDALLIARADRVQEVRRVVQRLK 356
Query: 344 EENDERAIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGT 403
+E E +HRT RPWGSYTVLEEG R+KIKRI V PG+RLSLQ+H+HRSEHW+VV+G
Sbjct: 357 DERHEAYRLHRTVNRPWGSYTVLEEGPRFKIKRIVVRPGERLSLQMHHHRSEHWIVVQGM 416
Query: 404 AKVVVGDKEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFG 463
A+V GD ++ EST+IPAG HRLENPG + L +IE Q GEYLGEDDIVR +D +G
Sbjct: 417 ARVTNGDGARLVNSNESTYIPAGHRHRLENPGVIDLVMIEVQSGEYLGEDDIVRFEDQYG 476
Query: 464 R 464
R
Sbjct: 477 R 477
>pir||T44446 D-rhamnose synthesis protein wbpW [imported] - Pseudomonas
aeruginosa >gi|3249549|gb|AAC72283.1| (AF009956) WbpW
[Pseudomonas aeruginosa]
Length = 479
Score = 393 bits (998), Expect = e-108
Identities = 217/481 (45%), Positives = 304/481 (63%), Gaps = 28/481 (5%)
Query: 4 LILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERAL-LFSKPKEIFIVTNKEYKF 62
++L+GG GTRLWP+SRE PK F+++ ++L KT RA L + EI VTN+E+ F
Sbjct: 5 VVLSGGAGTRLWPVSREGQPKPFMRLPDGQTLLGKTYRRAAGLLAGHGEIVTVTNREHYF 64
Query: 63 RVLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENYGDS-VVAVLPSDHAIKVN 121
+ D + L + +LEP G+NT PAI + +GD+ V+ V+P+DH I+
Sbjct: 65 QSKDQFHAARLGRHRGHFILEPTGRNTAPAIAVAALGLQAEHGDAAVLVVMPADHLIRNE 124
Query: 122 DNYMEAFKKAEKLAEK-YLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKEKP 180
+ + EA A +LA +LVTFG+ P TG+GYI+ G+++ +G V F EKP
Sbjct: 125 EAFREAVGHAARLAVAGHLVTFGVVPDAAETGFGYIELGDRLDEQGAA---KVRRFVEKP 181
Query: 181 DLETAKKYVENG-YYWNSGMFMFRTSVFMEEARKHAP---ETVRA---------FEEGKS 227
D ET ++YVE+G + WNSGMF F S ++E +HAP E RA +G
Sbjct: 182 DEETRRRYVESGGFLWNSGMFCFTASTLVDELAQHAPALLEQARACLAASAAVKMADGIQ 241
Query: 228 IE---EIYELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQV 284
E E + +P+IS+DY +ME++ + AVVP W+D+GS+ A+ LD D GN
Sbjct: 242 HELAGEGFAALPDISIDYALMERSARVAVVPAAFDWSDIGSWGAMSALLDADAEGNRGS- 300
Query: 285 AGFKAKYININSRNNLILTE-RLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLR 343
+ +++RN + ++ RL ATVGV+DL++VDT DALL+A+ Q+V+ V +RL+
Sbjct: 301 ----GDTLFVDTRNTFVQSDGRLVATVGVDDLVVVDTSDALLIARADRVQEVRRVVQRLK 356
Query: 344 EENDERAIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGT 403
+E E +HRT RPWGSYTVLEEG R+KIKRI V PG+RLSLQ+H+HRSEHW+VV+G
Sbjct: 357 DERHEAYRLHRTVNRPWGSYTVLEEGPRFKIKRIVVRPGERLSLQMHHHRSEHWIVVQGM 416
Query: 404 AKVVVGDKEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFG 463
A+V GD ++ EST+IPAG HRLENPG + L +IE Q GEYLGEDDIVR +D +G
Sbjct: 417 ARVTNGDGARLVNSNESTYIPAGHRHRLENPGVIDLVMIEVQSGEYLGEDDIVRFEDQYG 476
Query: 464 R 464
R
Sbjct: 477 R 477
>gb|AAC60775.1| (U46859) ManC [Yersinia enterocolitica (type 0:8)]
>gi|1588473|prf||2208415C mannose-1-phosphate
guanyltransferase [Yersinia enterocolitica]
Length = 465
Score = 379 bits (964), Expect = e-104
Identities = 202/470 (42%), Positives = 298/470 (62%), Gaps = 26/470 (5%)
Query: 4 LILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERALLFSKPKEIFIVTNKEYKFR 63
+I+AGG G+RLWPLSR PKQF+ + S+ S+FQ+T+ R L S ++ N E++F
Sbjct: 5 VIMAGGAGSRLWPLSRTHYPKQFLALTSELSMFQETLLR-LEISPHLSPLVICNAEHRFI 63
Query: 64 VLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENYGDSVVAVLPSDHAIKVNDN 123
+ + L + L I+LEP+G+NT PAI + N D ++ VL +DH I+
Sbjct: 64 IAEQLRQQNLL--HSGIVLEPIGRNTAPAIALAALLATSNGEDPILLVLAADHVIQDKPA 121
Query: 124 YMEAFKKAEKLAEK-YLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKEKPDL 182
++ A + AE LAE LVTFGI P P TGYGYI+ G++I EG + VD F EKPDL
Sbjct: 122 FISAIQLAEPLAEMGKLVTFGIVPNTPETGYGYIRQGKQI--EGGA--FQVDSFVEKPDL 177
Query: 183 ETAKKYVENG-YYWNSGMFMFRTSVFMEEARKHAPETVRAF-----EEGKSIEEI----- 231
A++Y+ +G YYWNSGMF+F+ S +++E KH P+ A + GK ++ I
Sbjct: 178 AKAEQYLSSGDYYWNSGMFVFKASRYLQELEKHRPDIFEACKSAIADNGKDLDFIRLDEA 237
Query: 232 -YELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAGFKAK 290
+ P+ S+DY +ME+T A VVP+N W+D+G + A++E DKD +GN V +
Sbjct: 238 AFYSCPDESIDYAVMERTSDAVVVPMNAQWSDVGCWSALWEINDKDSHGNVV-----RGD 292
Query: 291 YININSRNNLILTE-RLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLREENDER 349
+ ++ N+ I ++ RL ATVG+ DLIIV+T DALLVA + + Q VKE+ +L+ +
Sbjct: 293 VLTEDTNNSYIYSQNRLVATVGINDLIIVETKDALLVANKNKVQSVKEIVGQLKLGSRLE 352
Query: 350 AIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAKVVVG 409
+ H+ YRPWGS+ + EG RY ++ +T+ PG+R + QIH+HR+EHWVVV GTA+V
Sbjct: 353 YLQHKEVYRPWGSHDAIAEGVRYHVQHVTIKPGQRTATQIHHHRAEHWVVVSGTARVYRD 412
Query: 410 DKEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQ 459
++ +++ EST+I GV H +ENPGK+ LE+IE + G YL EDDIVR++
Sbjct: 413 NESYLVTENESTYIAVGVAHSIENPGKLPLEIIEVRTGSYLEEDDIVRIE 462
>sp|Q01410|MANC_SALMO MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE (GDP) (GDP-MANNOSE
PYROPHOSPHORYLASE) (GMP) >gi|281993|pir||S27676
mannose-1-phosphate guanyltransferase - Salmonella
choleraesuis >gi|154204|gb|AAB49390.1| (M84642)
mannose-1-phosphate guanyltransferase [Salmonella
enterica]
Length = 471
Score = 378 bits (961), Expect = e-104
Identities = 208/478 (43%), Positives = 296/478 (61%), Gaps = 29/478 (6%)
Query: 4 LILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERALLFSKPKEIFIVTNKEYKFR 63
+I+AGG G+RLWPLSR PKQF+ + +S+ Q T+ R + I ++ N++++F
Sbjct: 5 IIMAGGNGSRLWPLSRTLYPKQFLCLDGSQSMLQTTITRINNLNASDPI-VICNEQHRFI 63
Query: 64 VLDDLNELGLKVPEENILLEPVGKNTLPAIYWG-LKVIDENYGDSVVAVLPSDHAIKVND 122
V + L EL +I+LEPVG+NT PA+ LK + +N +++ VL +DH IK +
Sbjct: 64 VAEQLKELSKS--SGDIILEPVGRNTAPAVALAALKCLKKN---ALLLVLAADHIIKDEE 118
Query: 123 NYMEAFKKAEKLAEK-YLVTFGIKPTKPHTGYGYIKPGEKI--KVEGKTIGYLVDEFKEK 179
+ + + A K AE LVTFGI PT P TGYGYI+ G+ + ++ + V EF EK
Sbjct: 119 TFCKTIQDARKYAEAGKLVTFGIVPTMPETGYGYIRRGQALFSAENDCSLAFRVAEFVEK 178
Query: 180 PDLETAKKYVENG-YYWNSGMFMFRTSVFMEEARKHAPETVRAFEEGKSI---------- 228
P+LETA+ Y+++G YYWNSGMF+FR ++EE K P+ +A
Sbjct: 179 PNLETAQSYLDSGEYYWNSGMFLFRADRYIEEL-KIRPDIYKACSLAMESAVTDLDFIRV 237
Query: 229 -EEIYELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAGF 287
E+ + P+ S+DY +MEKT+ A VVPLN W+D+GS+ +++E DKD NGN
Sbjct: 238 DEDSFCACPDESIDYAVMEKTNDAVVVPLNAGWSDVGSWSSLWEISDKDSNGNVT----- 292
Query: 288 KAKYININSRNNLILTER-LTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLREEN 346
K ++ N+ N + E L VGV+DLI+V T DA+LVA Q VK++ ++++ EN
Sbjct: 293 KGDVLSHNADNCYLHAETGLVTAVGVKDLIVVQTKDAVLVANTNCVQDVKKIVEKIKLEN 352
Query: 347 DERAIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAKV 406
I HR YRPWG Y ++ GERY++KRITV PG+ +S Q HYHR+EHW++V GTAK+
Sbjct: 353 RHEHITHREVYRPWGKYDSIDFGERYQVKRITVKPGEGISEQQHYHRAEHWIIVAGTAKI 412
Query: 407 VVGDKEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFGR 464
+ + IL ES +IP GV H LENPGK+ LE+IE + G YLGEDDIVR D +GR
Sbjct: 413 TIKGEVKILTENESVYIPVGVKHCLENPGKIALELIEVRSGAYLGEDDIVRFSDKYGR 470
>emb|CAA57100.1| (X81320) phosphomannose isomerase and GDP-mannose pyrophosphorylase
[Acinetobacter calcoaceticus]
Length = 472
Score = 378 bits (960), Expect = e-104
Identities = 196/477 (41%), Positives = 297/477 (62%), Gaps = 29/477 (6%)
Query: 4 LILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERALLFSKPKEIFIVTNKEYKFR 63
+I+AGG GTRLWPLSR PKQF+K+ D + AL + ++ N+E++F
Sbjct: 8 VIMAGGSGTRLWPLSRTQYPKQFLKLSPDGYTLLQATLFALKNLDCADPLLICNEEHRFL 67
Query: 64 VLDDLNELGLKVPEENILLEPVGKNTLPAIYWGL--KVIDENYGDSVVAVLPSDHAIKVN 121
+ + E+G+ I+LEP GKNT PAI ++ D+++ VL +DH I
Sbjct: 68 AAEQMREIGISA---KIILEPEGKNTAPAITLAALYQIQQAQDSDTIMLVLAADHVITEQ 124
Query: 122 DNYMEAFKKAEKLAE-KYLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKEKP 180
D + ++ +A +LA+ LVTFGI PT TGYGYI+ G + G+ V F EKP
Sbjct: 125 DKFEQSITQALELAKLDKLVTFGIVPTHAETGYGYIEKGNS-----ELNGFQVQRFVEKP 179
Query: 181 DLETAKKYVENG-YYWNSGMFMFRTSVFMEEARKHAPET----VRAFEEGKSI------- 228
D TA++Y+E+ + WNS MFMF+ +++ E ++HA + V + ++ K+
Sbjct: 180 DAATAQEYLESQKFLWNSAMFMFKADIYLNELQQHAQDIYNSCVASMQDTKADLDFIRID 239
Query: 229 EEIYELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAGFK 288
+E ++ S+DY +ME+T A VVPL+ WND+GS+ A+++ DKD+ GN +Q
Sbjct: 240 KEAFKQCRSESIDYAVMEQTKDAVVVPLDANWNDVGSWSALWDIQDKDDQGNVIQ----- 294
Query: 289 AKYININSRNNLILTE-RLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLREEND 347
I + S+NN + +E RL + +GV++L++++T DA+LVA + + Q +K++ + ++E+
Sbjct: 295 GDVITVKSQNNYVFSESRLVSLLGVDNLVVIETKDAILVADKSKVQDIKKIVESIKEQGR 354
Query: 348 ERAIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAKVV 407
HR YRPWG Y ++ ERY++KRITV PG++LS+Q+H+HRSEHW+VV GTAK+
Sbjct: 355 TEHFCHREVYRPWGKYDSIDHAERYQVKRITVKPGQKLSIQMHHHRSEHWIVVNGTAKIH 414
Query: 408 VGDKEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFGR 464
G + F+L +ST+IP G H LENPGKV LE+IE Q G YLGEDDIVR +D +GR
Sbjct: 415 KGKESFLLTENQSTYIPLGEIHALENPGKVPLELIEVQSGSYLGEDDIVRFEDLYGR 471
>pir||T44334 hypothetical protein manC [imported] - Vibrio cholerae
>gi|3721688|dbj|BAA33638.1| (AB012957) probable
GDP-mannose pyrophosphorylase and phosphomannose
isomerase [Vibrio cholerae]
Length = 465
Score = 377 bits (957), Expect = e-103
Identities = 204/477 (42%), Positives = 305/477 (63%), Gaps = 33/477 (6%)
Query: 4 LILAGGKGTRLWPLSREAMPKQFIKVFSD-RSLFQKTVERALLFSKPKEIFIVTNKEYKF 62
++L+GG G+RLWPLSRE PKQ + + SL Q+T+ R + + +V N +++F
Sbjct: 6 VVLSGGVGSRLWPLSREHFPKQCLNLTDLLSSLLQQTLVRTNHLNVQSPL-VVCNDDHRF 64
Query: 63 RVLDDLNELGLKVPEENILLEPVGKNTLPAIYWG-LKVIDENYGDSVVAVLPSDHAIKVN 121
+ L ++G+K + ++LEPVG+NT PA+ +V+ + D ++ VLP+DH I+
Sbjct: 65 LIAQQLQDMGVKGAK--VMLEPVGRNTAPAVALAAFEVLQSDNEDVLMLVLPADHVIRDT 122
Query: 122 DNYMEAFKKAEKLAEKY-LVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKEKP 180
+ +A +A+ LAE LVTFGI PT+ TGYGYIK G+ VE +F EKP
Sbjct: 123 AAFEKAIAQAKVLAEAGGLVTFGITPTRAETGYGYIKAGQDSCVE---------KFVEKP 173
Query: 181 DLETAKKYVENG-YYWNSGMFMFRTSVFMEEARKHAPETVRAFEE--GKSIEEI------ 231
DL TA+ Y+E+G Y WNSGMF+F+ S ++ E ++H P A E G E++
Sbjct: 174 DLATAQSYLESGDYLWNSGMFLFQASQYLAELKQHRPAMYAAVESAYGNRTEDLDFIRIG 233
Query: 232 ---YELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAGFK 288
+ P S+DY IME T A VVP N W+D+G++DA+++ +KD N N V V
Sbjct: 234 TEAFTACPSESIDYAIMEPTQNAKVVPYNGDWSDIGAWDALHDYCEKDSNHN-VLVGDVM 292
Query: 289 AKYININSRNNLILTE-RLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLREEND 347
A+ ++ N+L+ E RL AT+GV +L++++T DA+L+ + ++Q VK++ R++ E
Sbjct: 293 AE----STTNSLVRAESRLVATIGVNNLVVIETADAVLIMDKDQSQDVKKIVSRIKAEGR 348
Query: 348 ERAIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAKVV 407
+ + H T +RPWG+Y ++ G+R+++KRI V PG++LS+Q+H+HR+EHWVVV GTAKV
Sbjct: 349 QEHMHHTTVHRPWGTYQTVDLGDRHQVKRIMVKPGEKLSVQMHHHRAEHWVVVSGTAKVQ 408
Query: 408 VGDKEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFGR 464
G++E +L EST+IP GV H LENPGK+ LE+IE Q G YLGEDDIVR D +GR
Sbjct: 409 NGEREILLTENESTYIPVGVVHALENPGKIPLELIEVQSGSYLGEDDIVRFSDRYGR 465
>pir||F82828 phosphomannose isomerase-GDP-mannose pyrophosphorylase XF0259
[imported] - Xylella fastidiosa (strain 9a5c)
>gi|9105074|gb|AAF83072.1|AE003879_7 (AE003879)
phosphomannose isomerase-GDP-mannose pyrophosphorylase
[Xylella fastidiosa]
Length = 482
Score = 377 bits (957), Expect = e-103
Identities = 209/474 (44%), Positives = 278/474 (58%), Gaps = 27/474 (5%)
Query: 4 LILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERALLFSKPKEIFIVTNKEYKFR 63
+IL+GG GTRLWPLSREA PKQF+ + S+ Q T RA + I +V N+E++F
Sbjct: 22 VILSGGSGTRLWPLSREAYPKQFLPLVGHHSMLQATWLRAAPVTTHSPI-VVANEEHRFI 80
Query: 64 VLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENYGDSVVAVLPSDHAIKVNDN 123
+ L LG V ILLEP G+NT PAI D ++ VLPSDH I+
Sbjct: 81 AAEQLQHLG--VYPSAILLEPTGRNTAPAIAVAALEATRTGNDPLLLVLPSDHVIRDEAA 138
Query: 124 YMEAFK-KAEKLAEKYLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKEKPDL 182
+ A AE A+ LVTFGI P P GYGYIK G V+ F EKPDL
Sbjct: 139 FQTAVHVAAEAAAQGKLVTFGITPNTPEIGYGYIK------ATGNDTIRPVERFIEKPDL 192
Query: 183 ETAKKYVENG-YYWNSGMFMFRTSVFMEEARKHAPETVRAFEEGKSI-----------EE 230
TA+ Y+ +G Y+WNSGMF+FR S ++ E P A + S +E
Sbjct: 193 ATAQSYLASGDYFWNSGMFLFRASRYLAELSTFQPAIAEACQRAWSAAKRDTDFIRLDKE 252
Query: 231 IYELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAGFKAK 290
+E P S+DY +ME T A VPL+ WND+GS+ A++E +D +GNA Q
Sbjct: 253 AFENSPADSIDYAVMEHTADAVAVPLDAGWNDVGSWSALHEVSKQDNDGNAHQ-----GD 307
Query: 291 YININSRNNLILTERLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLREENDERA 350
I I+ RN RL A VG+E++++V+T DALLV R Q VKE+ +++ A
Sbjct: 308 VIQIDCRNTYAYGSRLIAMVGLENVVVVETDDALLVGHRDSIQTVKEIVGKIKANGRPEA 367
Query: 351 IVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAKVVVGD 410
HR YRPWG+Y ++ G+R+++KRITV PG LSLQ+H+HR+EHW++V GTA+V G
Sbjct: 368 TWHRKVYRPWGAYDSIDTGQRFQVKRITVKPGGTLSLQMHHHRAEHWIIVSGTAEVTRGS 427
Query: 411 KEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFGR 464
+ +L +ST+IP GV HRL NPGK+ LE+IE Q G YLGEDDIVR +D +GR
Sbjct: 428 EILLLTENQSTYIPLGVTHRLRNPGKLPLELIEVQSGSYLGEDDIVRFEDTYGR 481
>pir||S70879 GDP-mannose pyrophosphorylase rfbM homolog - Vibrio cholerae
>gi|1230580|gb|AAC46245.1| (U47057) GDP-mannose
pyrophosphorylase [Vibrio cholerae O139]
>gi|3724319|dbj|BAA33608.1| (AB012956) probable
GDP-mannose pyrophosphorylase and phosphomannose
isomerase [Vibrio cholerae] >gi|1588974|prf||2209416D
GDP-mannose pyrophosphorylase [Vibrio cholerae]
Length = 465
Score = 375 bits (952), Expect = e-103
Identities = 204/477 (42%), Positives = 304/477 (62%), Gaps = 33/477 (6%)
Query: 4 LILAGGKGTRLWPLSREAMPKQFIKVFSD-RSLFQKTVERALLFSKPKEIFIVTNKEYKF 62
++L+GG G+RLWPLSRE PKQ + + SL Q+T+ R + + +V N +++F
Sbjct: 6 VVLSGGVGSRLWPLSREHFPKQCLNLTDLLSSLLQQTLVRTNHLNVQSPL-VVCNDDHRF 64
Query: 63 RVLDDLNELGLKVPEENILLEPVGKNTLPAIYWG-LKVIDENYGDSVVAVLPSDHAIKVN 121
+ L ++G+K + ++LEPVG+NT PA+ +V+ + D ++ VLP+DH I+
Sbjct: 65 LIAQQLQDMGVKGAK--VMLEPVGRNTAPAVALAAFEVLQSDNEDVLMLVLPADHVIRDT 122
Query: 122 DNYMEAFKKAEKLAEKY-LVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKEKP 180
+ +A +A+ LAE LVTFGI P + TGYGYIK G+ VE +F EKP
Sbjct: 123 AAFEKAIAQAKVLAEAGGLVTFGITPMRAETGYGYIKAGQDSCVE---------KFVEKP 173
Query: 181 DLETAKKYVENG-YYWNSGMFMFRTSVFMEEARKHAPETVRAFEE--GKSIEEI------ 231
DL TA+ Y+E+G Y WNSGMF+F+ S ++ E ++H P A E G E++
Sbjct: 174 DLATAQSYLESGDYLWNSGMFLFQASQYLAELKQHRPAMYAAVESAYGNRTEDLDFIRIG 233
Query: 232 ---YELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAGFK 288
+ P S+DY IME T A VVP N W+D+G++DA+++ +KD N N V V
Sbjct: 234 TEAFTACPSESIDYAIMEPTQNAKVVPYNGDWSDIGAWDALHDYCEKDSNHN-VLVGDVM 292
Query: 289 AKYININSRNNLILTE-RLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLREEND 347
A+ ++ N+L+ E RL ATVGV +L++++T DA+L+ + ++Q VK++ R++ E
Sbjct: 293 AE----STTNSLVRAESRLVATVGVNNLVVIETADAVLIMDKDQSQDVKKIVSRIKAEGR 348
Query: 348 ERAIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAKVV 407
+ + H T +RPWG+Y ++ G+R+++KRI V PG++LS+Q+H+HR+EHWVVV GTAKV
Sbjct: 349 QEHMHHTTVHRPWGTYQTVDLGDRHQVKRIMVKPGEKLSVQMHHHRAEHWVVVSGTAKVQ 408
Query: 408 VGDKEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFGR 464
G++E +L EST+IP GV H LENPGK+ LE+IE Q G YLGEDDIVR D +GR
Sbjct: 409 NGEREILLTENESTYIPVGVVHALENPGKIPLELIEVQSGSYLGEDDIVRFSDRYGR 465
>dbj|BAB03201.1| (AB046360) putative GOP-mannose phosphorylase [Actinobacillus
actinomycetemcomitans]
Length = 467
Score = 374 bits (949), Expect = e-102
Identities = 205/470 (43%), Positives = 293/470 (61%), Gaps = 31/470 (6%)
Query: 3 TLILAGGKGTRLWPLSREAMPKQFIKVFSDRSL--FQKTVERALLFSKPKEIFIVTNKEY 60
++I+AGG G+RLWPLSR PKQF+ + +L Q T++R S + I I+TN+++
Sbjct: 4 SVIMAGGSGSRLWPLSRSMFPKQFLALDKKNNLTMLQATIDRINQMSTSEPI-IITNEQH 62
Query: 61 KFRVLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENYGDSVVAVLPSDHAIKV 120
+F V + L E G+K I+LEPVGKNT PAI ++ D ++ VL +DH +
Sbjct: 63 RFIVAEQLREYGVK---SRIILEPVGKNTAPAIALAAFEAIKHGEDPILLVLAADHVVLN 119
Query: 121 NDNYMEAFKKAEKLAEK-YLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKEK 179
+ + + + A A+ YLVTFGI PT P TGYGYI+ GEKI E Y V+ F EK
Sbjct: 120 KEAFQTSVRNALVQAQTGYLVTFGIVPTAPETGYGYIQRGEKITEEA----YKVERFVEK 175
Query: 180 PDLETAKKYVENGY-YWNSGMFMFRTSVFMEEARKHAPETVRAFEEGKS----------- 227
P+ ETA+KYV +G YWNSG FMF+ S ++ E RK A E A E+ S
Sbjct: 176 PNFETAEKYVASGNCYWNSGCFMFKASCYLHELRKFALEIYEACEKATSNRLKNNDFIRV 235
Query: 228 -IEEIYELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAG 286
++E + P+ SVDY ++EKTDKA VVP++ W+D+GS+ A++E DKDEN N+
Sbjct: 236 DVDEFLKC-PDDSVDYAVIEKTDKAIVVPMDAGWSDVGSWSALWEVSDKDENQNS----- 289
Query: 287 FKAKYININSRNNLILT-ERLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLREE 345
+ I N+ I +L A VG+E+++IVDT DA+LVA R + Q+VK++ ++L++E
Sbjct: 290 YHGDVIMKNTSGCYIYAPNKLVAAVGLENIVIVDTKDAVLVADRSKVQEVKQIVEQLKKE 349
Query: 346 NDERAIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAK 405
+ HR YRPWG + +GERYK+ RITV PG+ Q+HYHR+EHW+VV G AK
Sbjct: 350 DRREYKEHREIYRPWGRSDAIAQGERYKVNRITVNPGESEETQVHYHRAEHWIVVSGMAK 409
Query: 406 VVVGDKEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDI 455
V G++E ++ +S +IP GVPH++ N GK+ LE+IE Q G YL +DD+
Sbjct: 410 VTKGEQESLITENQSIYIPVGVPHQIANLGKIPLELIEVQSGGYLDDDDV 459
>pir||E47677 guanosine diphosphomannose pyrophosphorylase, GDP-mannose
pyrophosphorylase - Salmonella choleraesuis
Length = 472
Score = 374 bits (949), Expect = e-102
Identities = 208/479 (43%), Positives = 296/479 (61%), Gaps = 30/479 (6%)
Query: 4 LILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERALLFSKPKEIFIVTNKEYKFR 63
+I+AGG G+RLWPLSR PKQF+ + +S+ Q T+ R + I ++ N++++F
Sbjct: 5 IIMAGGNGSRLWPLSRTLYPKQFLCLDGSQSMLQTTITRINNLNASDPI-VICNEQHRFI 63
Query: 64 VLDDLNELGLKVPEENILLEPVGKNTLPAIYWG-LKVIDENYGDSVVAVLPSDHAIKVND 122
V + L EL +I+LEPVG+NT PA+ LK + +N +++ VL +DH IK +
Sbjct: 64 VAEQLKELSKS--SGDIILEPVGRNTAPAVALAALKCLKKN---ALLLVLAADHIIKDEE 118
Query: 123 NYMEAFKKAEKLAEK-YLVTFGIKPTKPHTGYGYIKPGEKI--KVEGKTIGYLVDEFKEK 179
+ + + A K AE LVTFGI PT P TGYGYI+ G+ + ++ + V EF EK
Sbjct: 119 TFCKTIQDARKYAEAGKLVTFGIVPTMPETGYGYIRRGQALFSAENDCSLAFRVAEFVEK 178
Query: 180 PDLETAKKYVENG-YYWNSGMFMF-RTSVFMEEARKHAPETVRAFEEGKSI--------- 228
P+LETA+ Y+++G YYWNSGMF+F R ++EE K P+ +A
Sbjct: 179 PNLETAQSYLDSGEYYWNSGMFLFFRADRYIEEL-KIRPDIYKACSLAMESAVTDLDFIR 237
Query: 229 --EEIYELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAG 286
E+ + P+ S+DY +MEKT+ A VVPLN W+D+GS+ +++E DKD NGN
Sbjct: 238 VDEDSFCACPDESIDYAVMEKTNDAVVVPLNAGWSDVGSWSSLWEISDKDSNGNVT---- 293
Query: 287 FKAKYININSRNNLILTER-LTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLREE 345
K ++ N+ N + E L VGV+DLI+V T DA+LVA Q VK++ ++++ E
Sbjct: 294 -KGDVLSHNADNCYLHAETGLVTAVGVKDLIVVQTKDAVLVANTNCVQDVKKIVEKIKLE 352
Query: 346 NDERAIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAK 405
N I HR YRPWG Y ++ GERY++KRITV PG+ +S Q HYHR+EHW++V GTAK
Sbjct: 353 NRHEHITHREVYRPWGKYDSIDFGERYQVKRITVKPGEGISEQQHYHRAEHWIIVAGTAK 412
Query: 406 VVVGDKEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFGR 464
+ + + IL ES +IP GV H LENPGK+ LE+IE + G YLGEDDIVR D +GR
Sbjct: 413 ITIKGEVKILTENESVYIPVGVKHCLENPGKIALELIEVRSGAYLGEDDIVRFSDKYGR 471
>emb|CAB63302.1| (AJ251712) mannose-1-P guanylyltransferase [Yersinia
pseudotuberculosis]
Length = 468
Score = 371 bits (942), Expect = e-101
Identities = 196/473 (41%), Positives = 297/473 (62%), Gaps = 30/473 (6%)
Query: 4 LILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVER--ALLFSKPKEIFIVTNKEYK 61
+I+AGG G+RLWPLSR PKQF+ + SD ++ Q+T+ R L P ++ N+E++
Sbjct: 5 VIMAGGAGSRLWPLSRALYPKQFLALTSDLTMLQETLLRLDGLPHLAP---LVICNEEHR 61
Query: 62 FRVLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENYGDSVVAVLPSDHAIKVN 121
F + + L + L I+LEPVG+NT PAI + D ++ VL +DH I+
Sbjct: 62 FIIAEQLRQKNLV--HSGIVLEPVGRNTAPAIALSALRATMSGDDPLLLVLAADHVIQDK 119
Query: 122 DNYMEAFKKAEKLAEK-YLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKEKP 180
++ A ++AE LAE LVTFGI P P TGYGYI+ G+++ V+G Y V F EKP
Sbjct: 120 LAFIRAVQRAEPLAEAGKLVTFGIVPKSPETGYGYIRQGKQV-VDG---AYQVAAFVEKP 175
Query: 181 DLETAKKYVENG-YYWNSGMFMFRTSVFMEEARKHAPETVRAFEEG-----------KSI 228
DL TA++Y+ +G YYWNSGMF+F+ S +++E H P+ + A ++ +
Sbjct: 176 DLITAERYLASGDYYWNSGMFVFKASRYLQELDLHRPDILAACKQAIAGQHTDLDFIRLN 235
Query: 229 EEIYELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAGFK 288
EE + P+ S+DY +MEKT A VVPL+ WND+G + A++E KD++GN + +
Sbjct: 236 EEAFSSCPDESIDYAVMEKTSDAVVVPLDAQWNDVGCWSALWEINTKDDHGNVI-----R 290
Query: 289 AKYININSRNNLILTE-RLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLREEND 347
+ ++ N+ + ++ RL ATVG+ DL+IV+T DA+LVA + + Q VK + +L+ E+
Sbjct: 291 GDVLIEDTNNSYVYSQNRLIATVGINDLVIVETKDAILVAHKDKVQNVKGIVGQLKLESR 350
Query: 348 ERAIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAKVV 407
+ HR YRPWGS+ + EG RY ++ +TV PG+R++ QIHYHR+EHW+VV G AKV
Sbjct: 351 CEYLQHREVYRPWGSHDAIAEGVRYHVQHVTVKPGQRIATQIHYHRAEHWIVVSGIAKVH 410
Query: 408 VGDKEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQD 460
G + +++ EST+IP G+ H +ENPG++ LE+IE G Y+ EDD+ R+ D
Sbjct: 411 YGKETYLVNENESTYIPVGIAHSIENPGQIPLEIIEVHTGNYISEDDVERIDD 463
>emb|CAB63283.1| (AJ251713) mannose-1-P guanylyltransferase [Yersinia pestis]
Length = 468
Score = 371 bits (942), Expect = e-101
Identities = 196/473 (41%), Positives = 297/473 (62%), Gaps = 30/473 (6%)
Query: 4 LILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVER--ALLFSKPKEIFIVTNKEYK 61
+I+AGG G+RLWPLSR PKQF+ + SD ++ Q+T+ R L P ++ N+E++
Sbjct: 5 VIMAGGAGSRLWPLSRALYPKQFLALTSDLTMLQETLLRLDGLPHLAP---LVICNEEHR 61
Query: 62 FRVLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENYGDSVVAVLPSDHAIKVN 121
F + + L + L I+LEPVG+NT PAI + D ++ VL +DH I+
Sbjct: 62 FIIAEQLRQKNLV--HSGIVLEPVGRNTAPAIALAALRATMSGDDPLLLVLAADHVIQDK 119
Query: 122 DNYMEAFKKAEKLAEK-YLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKEKP 180
++ A ++AE LAE LVTFGI P P TGYGYI+ G+++ V+G Y V F EKP
Sbjct: 120 LAFIRAVQRAEPLAEAGKLVTFGIVPKSPETGYGYIRQGKQV-VDG---AYQVAAFVEKP 175
Query: 181 DLETAKKYVENG-YYWNSGMFMFRTSVFMEEARKHAPETVRAFEEG-----------KSI 228
DL TA++Y+ +G YYWNSGMF+F+ S +++E H P+ + A ++ +
Sbjct: 176 DLITAERYLASGDYYWNSGMFVFKASRYLQELDLHRPDILAACKQAIAGQHTDLDFIRLN 235
Query: 229 EEIYELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAGFK 288
EE + P+ S+DY +MEKT A VVPL+ WND+G + A++E KD++GN + +
Sbjct: 236 EEAFSSCPDESIDYAVMEKTSDAVVVPLDAQWNDVGCWSALWEINTKDDHGNVI-----R 290
Query: 289 AKYININSRNNLILTE-RLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLREEND 347
+ ++ N+ + ++ RL ATVG+ DL+IV+T DA+LVA + + Q VK + +L+ E+
Sbjct: 291 GDVLIEDTNNSYVYSQNRLIATVGINDLVIVETKDAILVAHKDKVQNVKGIVGQLKLESR 350
Query: 348 ERAIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAKVV 407
+ HR YRPWGS+ + EG RY ++ +TV PG+R++ QIHYHR+EHW+VV G AKV
Sbjct: 351 CEYLQHREVYRPWGSHDAIAEGVRYHVQHVTVKPGQRIATQIHYHRAEHWIVVSGIAKVH 410
Query: 408 VGDKEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQD 460
G + +++ EST+IP G+ H +ENPG++ LE+IE G Y+ EDD+ R+ D
Sbjct: 411 YGKETYLVNENESTYIPVGIAHSIENPGQIPLEIIEVHTGNYISEDDVERIDD 463
>pir||B83201 phosphomannose isomerase / guanosine 5'-diphospho-D-mannose
pyrophosphorylase PA3551 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9949703|gb|AAG06939.1|AE004776_2 (AE004776)
phosphomannose isomerase / guanosine
5'-diphospho-D-mannose pyrophosphorylase [Pseudomonas
aeruginosa]
Length = 481
Score = 370 bits (940), Expect = e-101
Identities = 202/479 (42%), Positives = 291/479 (60%), Gaps = 26/479 (5%)
Query: 1 MKTLILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERALLFSKPKEIFIVTNKEY 60
M +IL+GG G+RLWPLSR+ PKQF+ + D +LFQ+T++R L F + +V NKE+
Sbjct: 1 MIPVILSGGSGSRLWPLSRKQYPKQFLALTGDDTLFQQTIKR-LAFDGMQAPLLVCNKEH 59
Query: 61 KFRVLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENYGDSVVAVLPSDHAIKV 120
+F V + L L + ILLEP G+NT PA+ + D ++ +LP+DH I+
Sbjct: 60 RFIVQEQLEAQNLA--SQAILLEPFGRNTAPAVAIAAMKLVAEGRDELLLILPADHVIED 117
Query: 121 NDNYMEAFKKAEKLAEK-YLVTFGIKPTKPHTGYGYIKPGEKIKV-EGKTIGYLVDEFKE 178
+ +A A AEK +V FGI ++P TGYGYI+ ++ EG + V F E
Sbjct: 118 QRAFQQALALATNAAEKGEMVLFGIPASRPETGYGYIRASADAQLPEGVS---RVQSFVE 174
Query: 179 KPDLETAKKYVE-NGYYWNSGMFMFRTSVFMEEARKHAPETV--------RAFEEGKSIE 229
KPD A+++V GYYWNSGMF+FR S ++EE +KH + R+ +G +
Sbjct: 175 KPDEARAREFVAAGGYYWNSGMFLFRASRYLEELKKHDADIYDTCLLALERSQHDGDLVN 234
Query: 230 ---EIYELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAG 286
+E P+ S+DY +MEKT +A VVPL+ WND+GS+ ++++ KD NGN
Sbjct: 235 IDAATFECCPDNSIDYAVMEKTSRACVVPLSAGWNDVGSWSSIWDVHAKDANGNVT---- 290
Query: 287 FKAKYININSRNNLILTE-RLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLREE 345
K + +S N L+ +L + +G+ED+++V+T DA+++A + Q VK V K L +
Sbjct: 291 -KGDVLVHDSHNCLVHGNGKLVSVIGLEDIVVVETKDAMMIAHKDRVQDVKHVVKDLDAQ 349
Query: 346 NDERAIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAK 405
H YRPWGSY ++ G R+++K ITV PG RLSLQ+H+HR+EHW+VV GTA+
Sbjct: 350 GRSETQNHCEVYRPWGSYDSVDMGGRFQVKHITVKPGARLSLQMHHHRAEHWIVVSGTAQ 409
Query: 406 VVVGDKEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFGR 464
V DK F+L +ST+IP HRL NPGK+ LE+IE Q G YLGEDDI RL+D +GR
Sbjct: 410 VTCDDKTFLLTENQSTYIPIASVHRLANPGKIPLEIIEVQSGSYLGEDDIERLEDVYGR 468
>sp|Q48462|MANC_KLEPN MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE (GDP) (GDP-MANNOSE
PYROPHOSPHORYLASE) (GMP) (ORF16) >gi|1361275|pir||E56146
cpsB protein homolog - Klebsiella pneumoniae
>gi|747676|dbj|BAA04787.1| (D21242) ORF16 [Klebsiella
pneumoniae]
Length = 471
Score = 369 bits (938), Expect = e-101
Identities = 203/475 (42%), Positives = 287/475 (59%), Gaps = 23/475 (4%)
Query: 4 LILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERALLFSKPKEIFIVTNKEYKFR 63
+I+AGG G+RLWP+SRE PKQF+++F S+ Q+T+ R L + E ++ N+E++F
Sbjct: 5 VIMAGGTGSRLWPMSRELYPKQFLRLFGQNSMLQETITR-LSGLEIHEPMVICNEEHRFL 63
Query: 64 VLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENYGDSVVAVLPSDHAIKVNDN 123
V + L +L NI+LEPVG+NT PAI + D ++ VL +DH I
Sbjct: 64 VAEQLRQLNKL--SNNIILEPVGRNTAPAIALAALQATRHGDDPLMLVLAADHIINNQPV 121
Query: 124 YMEAFKKAEKLAEK-YLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKEKPDL 182
+ +A + AE+ A++ +LVTFGI P P TGYGYI+ G + T Y V F EKPD
Sbjct: 122 FHDAIRVAEQYADEGHLVTFGIVPNAPETGYGYIQRGVALTDSAHT-PYQVARFVEKPDR 180
Query: 183 ETAKKYVENG-YYWNSGMFMFRTSVFMEEARKHAPE-------TVRAFEEGKSI----EE 230
E A+ Y+ +G YYWNSGMFMFR ++ E K P+ V A + G +
Sbjct: 181 ERAEAYLASGEYYWNSGMFMFRAKKYLSELAKFRPDILEACQAAVNAADNGSDFISIPHD 240
Query: 231 IYELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAGFKAK 290
I+ P+ SVDY +MEKT A VV L+ W+D+GS+ A++E KDE GN + +
Sbjct: 241 IFCECPDESVDYAVMEKTADAVVVGLDADWSDVGSWSALWEVSPKDEQGNVLSGDAWVH- 299
Query: 291 YININSRNNLILT-ERLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLREENDER 349
NS N I + E+L A +GVE+L+IV T DA+LV R +Q VK+ + L++
Sbjct: 300 ----NSENCYINSDEKLVAAIGVENLVIVSTKDAVLVMNRERSQDVKKAVEFLKQNQRSE 355
Query: 350 AIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAKVVVG 409
HR YRPWG V+ + R+ + RITV PG S+Q+H+HR+EHWV++ GT +V V
Sbjct: 356 YKRHREIYRPWGRCDVVVQTPRFNVNRITVKPGGAFSMQMHHHRAEHWVILAGTGQVTVN 415
Query: 410 DKEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFGR 464
K+F+L +STFIP G H LENPG++ LEV+E Q G YLGEDDI+R++D +GR
Sbjct: 416 GKQFLLTENQSTFIPIGAEHSLENPGRIPLEVLEIQSGSYLGEDDIIRIKDQYGR 470
>emb|CAA69110.1| (Y07786) guanylyl transferase [Vibrio cholerae]
Length = 460
Score = 368 bits (934), Expect = e-101
Identities = 201/471 (42%), Positives = 302/471 (63%), Gaps = 35/471 (7%)
Query: 4 LILAGGKGTRLWPLSREAMPKQFIKVFSD--RSLFQKTVERALLFSKPKEIFIVTNKEYK 61
++L+GG G+RLWPLSRE PKQ + + +D SL Q+T+ R + + + +V N +++
Sbjct: 6 VVLSGGVGSRLWPLSREHFPKQCL-ILTDLLSSLLQQTLVRTIHLNVQSPL-VVCNDDHR 63
Query: 62 FRVLDDLNELGLKVPEENILLEPVGKNTLPAIYWG-LKVIDENYGDSVVAVLPSDHAIKV 120
F + L ++G+K + ++LEPVG+NT PA+ +V+ + D ++ VLP+DH I+
Sbjct: 64 FLIAQQLQDMGVKGAK--VMLEPVGRNTAPAVALAAFEVLQSDNEDVLMLVLPADHVIRD 121
Query: 121 NDNYMEAFKKAEKLAEKY-LVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKEK 179
+ +A +A+ LAE LVTFGI P + TGYGYIK G+ VE +F EK
Sbjct: 122 TAAFEKAIAQAKVLAEAGGLVTFGITPMRAETGYGYIKAGQDSCVE---------KFVEK 172
Query: 180 PDLETAKKYVENG-YYWNSGMFMFRTSVFMEEARKHAPETVRAFEE--GKSIEEI----- 231
PDL TA+ Y+E+G Y WNSGMF+F+ S ++ E +H P A E G E++
Sbjct: 173 PDLATAQSYLESGDYLWNSGMFLFQASQYLAELTQHRPAMYAAVESAYGNRTEDLDFIRI 232
Query: 232 ----YELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAGF 287
+ P S+DY IME T A VVP N W+D+G++DA+++ +KD N + V V
Sbjct: 233 GTEAFTACPSESIDYAIMEPTQNAKVVPYNGDWSDIGAWDALHDYCEKDSN-HIVLVGDV 291
Query: 288 KAKYININSRNNLILTE-RLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLREEN 346
A+ ++ N+L+ E RL ATVGV +L++++T DA+L+ + ++Q VK++ R++ E
Sbjct: 292 MAE----STTNSLVRAESRLVATVGVNNLVVIETADAVLIMDKDQSQDVKKIVSRIKAEG 347
Query: 347 DERAIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAKV 406
+ + H T +RPWG+Y ++ G+R+++KRI V PG++LS+Q+H+HR+EHWVVV GTAKV
Sbjct: 348 RQEHMHHTTVHRPWGTYQTVDLGDRHQVKRIMVKPGEKLSVQMHHHRAEHWVVVSGTAKV 407
Query: 407 VVGDKEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVR 457
G++E +L EST+IP GV H LENPGK+ LE+IE Q G YLGEDDIVR
Sbjct: 408 QNGEREILLTENESTYIPVGVVHALENPGKIPLELIEVQSGSYLGEDDIVR 458
>pir||H64970 mannose-1-phosphate guanylyltransferase (GDP) (EC 2.7.7.22) -
Escherichia coli >gi|1736755|dbj|BAA15905.1| (D90843)
Mannose-1-phosphate guanylyltransferase (GDP) (EC
2.7.7.22) (GDP- Mannose pyrophosphorylase) (GMP).
[Escherichia coli] >gi|1788362|gb|AAC75110.1| (AE000295)
mannose-1-phosphate guanyltransferase [Escherichia coli
K12]
Length = 478
Score = 367 bits (932), Expect = e-100
Identities = 201/477 (42%), Positives = 287/477 (60%), Gaps = 24/477 (5%)
Query: 4 LILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERALLFSKPKEIFIVTNKEYKFR 63
+++AGG G+RLWPLSR PKQF+ + D ++ Q T+ R L + + ++ N++++F
Sbjct: 9 VVMAGGSGSRLWPLSRVLYPKQFLCLKGDLTMLQTTICR-LNGVECESPVVICNEQHRFI 67
Query: 64 VLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENY--GDSVVAVLPSDHAIKVN 121
V + L +L ENI+LEP G+NT PAI + D ++ VL +DH I
Sbjct: 68 VAEQLRQLNKLT--ENIILEPAGRNTAPAIALAALAAKRHSPESDPLMLVLAADHVIADE 125
Query: 122 DNYMEAFKKAEKLAEK-YLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKEKP 180
D + A + A AE LVTFGI P P TGYGYI+ GE E + + V +F EKP
Sbjct: 126 DAFRAAVRNAMPYAEAGKLVTFGIVPDLPETGYGYIRRGEVSAGEQDMVAFEVAQFVEKP 185
Query: 181 DLETAKKYVENG-YYWNSGMFMFRTSVFMEEARKHAPETVRAFEEGKSI----------- 228
+LETA+ YV +G YYWNSGMF+FR ++EE +K+ P+ + A E+ S
Sbjct: 186 NLETAQAYVASGEYYWNSGMFLFRAGRYLEELKKYRPDILDACEKAMSAVDPDLNFIRVD 245
Query: 229 EEIYELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAGFK 288
EE + PE SVDY +ME+T A VVP++ W+D+GS+ +++E GN
Sbjct: 246 EEAFLACPEESVDYAVMERTADAVVVPMDAGWSDVGSWSSLWEISAHTAEGNVCH----- 300
Query: 289 AKYININSRNNLILTER-LTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLREEND 347
IN + N+ + E L TVGV+DL++V T DA+L+A R Q VK+V ++++ +
Sbjct: 301 GDVINHKTENSYVYAESGLVTTVGVKDLVVVQTKDAVLIADRNAVQDVKKVVEQIKADGR 360
Query: 348 ERAIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAKVV 407
VHR YRPWG Y ++ G+RY++KRITV PG+ LS+Q+H+HR+EHWVVV GTAKV
Sbjct: 361 HEHRVHREVYRPWGKYDSIDAGDRYQVKRITVKPGEGLSVQMHHHRAEHWVVVAGTAKVT 420
Query: 408 VGDKEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFGR 464
+ +L ES +IP G H LENPGK+ L++IE + G YL EDD+VR D +GR
Sbjct: 421 IDGDIKLLGENESIYIPLGATHCLENPGKIPLDLIEVRSGSYLEEDDVVRFADRYGR 477
>pir||H82345 mannose-1-phosphate guanylyltransferase VC0241 [imported] - Vibrio
cholerae (group O1 strain N16961)
>gi|9654650|gb|AAF93417.1| (AE004113)
mannose-1-phosphate guanylyltransferase [Vibrio
cholerae]
Length = 465
Score = 367 bits (932), Expect = e-100
Identities = 197/474 (41%), Positives = 287/474 (59%), Gaps = 31/474 (6%)
Query: 4 LILAGGKGTRLWPLSREAMPKQFIKV--FSDRSLFQKTVER--ALLFSKPKEIFIVTNKE 59
+I+AGG G+RLWPLSR A PKQF+ + S ++ Q T+ER L ++P +++N++
Sbjct: 5 VIMAGGSGSRLWPLSRSAFPKQFLSLDSSSQHTMLQATIERLQGLPIAEP---IVISNED 61
Query: 60 YKFRVLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENYGDSVVAVLPSDHAIK 119
++F V + + G K I+LEP G+NT PAI E D V+ VL +DH +K
Sbjct: 62 HRFIVAEQIRRYGKK---SRIILEPAGRNTAPAIALAAFTAIEQEDDPVLLVLAADHFVK 118
Query: 120 VNDNYMEAFKKAEKLAEK-YLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKE 178
+ A +A + AE L TFGI PT P TGYGYI GE++ +G Y ++ F E
Sbjct: 119 NKSAFQAAISQAAQQAEAGKLATFGIVPTTPETGYGYIHRGEEV-TQGT---YEINSFVE 174
Query: 179 KPDLETAKKYVENG-YYWNSGMFMFRTSVFMEEARKHAPETVRAFEEG-KSIEEIYELV- 235
KP L A++Y+ +G YYWNSG FMF+ SVF+ E ++H+PE R E + + Y+ +
Sbjct: 175 KPQLNIAEQYLASGEYYWNSGCFMFKASVFLNELKQHSPEIYRQCELAMQGLSHDYDFIR 234
Query: 236 ---------PEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAG 286
P+ S+DY +ME T VV ++ W+D+GS+ A++E DKD +GN Q
Sbjct: 235 VGVEEFLKCPDDSIDYAVMEHTKLGVVVSMDAGWSDVGSWSALWEVSDKDADGNVCQGDA 294
Query: 287 FKAKYININSRNNLILTERLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLREEN 346
++ S + +L A VG++D+++V+T DA+LVA + + Q+VK++ + L+ EN
Sbjct: 295 I----LSGTSNCYIYAPNKLVAAVGLKDIVVVETKDAVLVADKNQVQEVKKIVEHLKAEN 350
Query: 347 DERAIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAKV 406
HR YRPWG +++GERYK+ RITV PGK+ SLQ+HYHR+EHWVVV GTAKV
Sbjct: 351 RAEYREHRERYRPWGKSDAIDKGERYKVNRITVEPGKKQSLQMHYHRAEHWVVVSGTAKV 410
Query: 407 VVGDKEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQD 460
++ +S +IP G H +ENPGK+ LE+IE Q G YL EDD+VR +D
Sbjct: 411 TCEGNVKVITENQSLYIPIGTNHMIENPGKIPLELIEIQSGSYLNEDDVVRFED 464
>pir||I57096 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) - Escherichia
coli >gi|598465|dbj|BAA07745.1| (D43637) GDP-mannose
pyrophosphorylase [Escherichia coli]
Length = 471
Score = 367 bits (931), Expect = e-100
Identities = 202/475 (42%), Positives = 286/475 (59%), Gaps = 23/475 (4%)
Query: 4 LILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERALLFSKPKEIFIVTNKEYKFR 63
+I+AGG G+RLWP+SRE PKQF+++F S+ Q+T+ R L + E ++ N+E++F
Sbjct: 5 VIMAGGTGSRLWPMSRELYPKQFLRLFGQNSMLQETITR-LSGLEIHEPMVICNEEHRFL 63
Query: 64 VLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENYGDSVVAVLPSDHAIKVNDN 123
V + L +L NI+LEPVG+NT PAI + D ++ VL +DH I
Sbjct: 64 VAEQLRQLNKL--SNNIILEPVGRNTAPAIALAALQATRHGDDPLMLVLAADHIINNQPV 121
Query: 124 YMEAFKKAEKLAEK-YLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKEKPDL 182
+ +A + AE+ A++ +LVTFGI P P TGYGYI+ G + T Y V F EKPD
Sbjct: 122 FHDAIRVAEQYADEGHLVTFGIVPNAPETGYGYIQRGVALTDSAHT-PYQVARFVEKPDR 180
Query: 183 ETAKKYVENG-YYWNSGMFMFRTSVFMEEARKHAPE-------TVRAFEEGKSI----EE 230
E A+ Y+ +G YYWNSGMFMFR ++ E K P+ V A + G +
Sbjct: 181 ERAEAYLASGEYYWNSGMFMFRAKKYLSELAKFRPDILEACQAAVNAADNGSDFISIPHD 240
Query: 231 IYELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAGFKAK 290
I+ P+ SVDY +MEKT A VV L+ W+D+GS+ A++E KD GN + +
Sbjct: 241 IFCECPDESVDYAVMEKTADAVVVGLDADWSDVGSWSALWEVSPKDGQGNVLSGDAWVH- 299
Query: 291 YININSRNNLILT-ERLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLREENDER 349
NS N I + E+L A +GVE+L+IV T DA+LV R +Q VK+ + L++
Sbjct: 300 ----NSENCYINSDEKLVAAIGVENLVIVSTKDAVLVMNRERSQDVKKAVEFLKQNQRSE 355
Query: 350 AIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAKVVVG 409
HR YRPWG V+ + R+ + RITV PG S+Q+H+HR+EHWV++ GT +V V
Sbjct: 356 YKRHREIYRPWGRCDVVVQTPRFNVNRITVKPGGAFSMQMHHHRAEHWVILAGTGQVTVN 415
Query: 410 DKEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFGR 464
K+F+L +STFIP G H LENPG++ LEV+E Q G YLGEDDI+R++D +GR
Sbjct: 416 GKQFLLTENQSTFIPIGAEHSLENPGRIPLEVLEIQSGSYLGEDDIIRIKDQYGR 470
>sp|P07874|ALGA_PSEAE ALGINATE BIOSYNTHESIS PROTEIN ALGA [INCLUDES: MANNOSE-6-PHOSPHATE
ISOMERASE (PHOSPHOMANNOSE ISOMERASE) (PMI)
(PHOSPHOHEXOMUTASE); MANNOSE-1-PHOSPHATE GUANYLYL
TRANSFERASE (GDP) (GDP-MANNOSE PYROPHOSPHORYLASE) (GMP)]
>gi|94793|pir||A38598 mannose-6-phosphate isomerase (EC
5.3.1.8) / mannose-1-phosphate guanylyltransferase (GDP)
(EC 2.7.7.22) - Pseudomonas aeruginosa
>gi|151504|gb|AAA25972.1| (M14037) phosphomannose
isomerase [Pseudomonas aeruginosa]
Length = 481
Score = 366 bits (930), Expect = e-100
Identities = 200/479 (41%), Positives = 290/479 (59%), Gaps = 26/479 (5%)
Query: 1 MKTLILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERALLFSKPKEIFIVTNKEY 60
M +IL+GG G+RLWPLSR+ PKQ + + D +LFQ+T++R L F + +V NKE+
Sbjct: 1 MIPVILSGGSGSRLWPLSRKQYPKQLVALTGDDTLFQQTIKR-LAFDGMQAPLLVCNKEH 59
Query: 61 KFRVLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENYGDSVVAVLPSDHAIKV 120
+F V + L L + ILLEP G+NT PA+ + D ++ +LP+DH ++
Sbjct: 60 RFIVQEQLEAQNLA--SQAILLEPFGRNTAPAVAIAAMKLVAEGRDELLLILPADHVLED 117
Query: 121 NDNYMEAFKKAEKLAEK-YLVTFGIKPTKPHTGYGYIKPGEKIKV-EGKTIGYLVDEFKE 178
+ +A A AEK +V FGI ++P TGYGYI+ ++ EG + V F E
Sbjct: 118 QRAFQQALALATNAAEKGEMVLFGIPASRPETGYGYIRATADAQLPEGVS---RVQSFVE 174
Query: 179 KPDLETAKKYVE-NGYYWNSGMFMFRTSVFMEEARKHAPETV--------RAFEEGKSIE 229
KPD A+++V GYYWNSGMF+FR S ++EE +KH + R+ +G +
Sbjct: 175 KPDEARAREFVAAGGYYWNSGMFLFRASRYLEELKKHDADIYDTCLLALERSQHDGDLVN 234
Query: 230 ---EIYELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAG 286
+E P+ S+DY +MEKT +A VVPL+ WND+GS+ ++++ KD NGN
Sbjct: 235 IDAATFECCPDNSIDYAVMEKTSRACVVPLSAGWNDVGSWSSIWDVHAKDANGNVT---- 290
Query: 287 FKAKYININSRNNLILTE-RLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLREE 345
K + +S N L+ +L + +G+ED+++V+T DA+++A + Q VK V K L +
Sbjct: 291 -KGDVLVHDSHNCLVHGNGKLVSVIGLEDIVVVETKDAMMIAHKDRVQDVKHVVKDLDAQ 349
Query: 346 NDERAIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAK 405
H YRPWGSY ++ G R+++K ITV PG RLSLQ+H+HR+EHW+VV GTA+
Sbjct: 350 GRSETQNHCDLYRPWGSYDSVDMGGRFQVKHITVKPGARLSLQMHHHRAEHWIVVSGTAQ 409
Query: 406 VVVGDKEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFGR 464
V DK F+L +ST+IP HRL NPGK+ LE+IE Q G YLGEDDI RL+D +GR
Sbjct: 410 VTCDDKTFLLTENQSTYIPIASVHRLANPGKIPLEIIEVQSGSYLGEDDIERLEDVYGR 468
>sp|P24174|MANC_ECOLI MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE (GDP) (GDP-MANNOSE
PYROPHOSPHORYLASE) (GMP) >gi|1073349|pir||A55239 cpsB
protein - Escherichia coli >gi|1407616|gb|AAC77846.1|
(U38473) mannose-1-P guanosyltransferase [Escherichia
coli]
Length = 478
Score = 366 bits (929), Expect = e-100
Identities = 200/477 (41%), Positives = 287/477 (59%), Gaps = 24/477 (5%)
Query: 4 LILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERALLFSKPKEIFIVTNKEYKFR 63
+++AGG G+RLWPLSR PKQF+ + D ++ Q T+ R L + + ++ N++++F
Sbjct: 9 VVMAGGSGSRLWPLSRVLYPKQFLCLKGDLTMLQTTICR-LNGVECESPVVICNEQHRFI 67
Query: 64 VLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENY--GDSVVAVLPSDHAIKVN 121
V + L +L ENI+LEP G+NT PAI + D ++ VL +DH I
Sbjct: 68 VAEQLRQLNKLT--ENIILEPAGRNTAPAIALAALAAKRHSPESDPLMLVLAADHVIADE 125
Query: 122 DNYMEAFKKAEKLAEK-YLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKEKP 180
D + A + A AE LVTFGI P P TGYGYI+ GE E + + V +F EKP
Sbjct: 126 DAFRAAVRNAMPYAEAGKLVTFGIVPDLPETGYGYIRRGEVSAGEQDMVAFEVAQFVEKP 185
Query: 181 DLETAKKYVENG-YYWNSGMFMFRTSVFMEEARKHAPETVRAFEEGKSI----------- 228
+LETA+ YV +G YYWNSGMF+FR ++EE +K+ P+ + A E+ S
Sbjct: 186 NLETAQAYVASGEYYWNSGMFLFRAGRYLEELKKYRPDILDACEKAMSAVDPDLNFIRVD 245
Query: 229 EEIYELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAGFK 288
EE + PE SVDY +ME+T A VVP++ W+D+GS+ +++E GN
Sbjct: 246 EEAFLACPEESVDYAVMERTADAVVVPMDAGWSDVGSWSSLWEISAHTAEGNVCH----- 300
Query: 289 AKYININSRNNLILTER-LTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLREEND 347
IN + N+ + E L TVG++DL++V T DA+L+A R Q VK+V ++++ +
Sbjct: 301 GDVINHKTENSYVYAESGLVTTVGLKDLVVVQTKDAVLIADRNAVQDVKKVVEQIKADGR 360
Query: 348 ERAIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAKVV 407
VHR YRPWG Y ++ G+RY++KRITV PG+ LS+Q+H+HR+EHWVVV GTAKV
Sbjct: 361 HEHRVHREVYRPWGKYDSIDAGDRYQVKRITVKPGEGLSVQMHHHRAEHWVVVAGTAKVT 420
Query: 408 VGDKEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFGR 464
+ +L ES +IP G H LENPGK+ L++IE + G YL EDD+VR D +GR
Sbjct: 421 IDGDIKLLGENESIYIPLGATHCLENPGKIPLDLIEVRSGSYLEEDDVVRFADRYGR 477
>pir||A25638 mannose-6-phosphate isomerase (EC 5.3.1.8) - Pseudomonas aeruginosa
Length = 480
Score = 365 bits (926), Expect = e-100
Identities = 203/480 (42%), Positives = 293/480 (60%), Gaps = 29/480 (6%)
Query: 1 MKTLILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERALLFSKPKEIFIVTNKEY 60
M +IL+GG G+RLWPLSR+ PKQF+ + D +LFQ+T++R L F + +V NK +
Sbjct: 1 MIPVILSGGSGSRLWPLSRKQYPKQFLALTGDDTLFQQTLKR-LAFDGMQAPLLVCNKAH 59
Query: 61 KFRVLDDLNELGLKVPEENILLEPVGKNTLPAI-YWGLKVIDENYGDSVVAVLPSDHAIK 119
+F V + L L + ILLEP G+NT PA+ +K++ E G + +LP+DH I+
Sbjct: 60 RFIVQEQLEAQNLA--SQAILLEPFGRNTAPAVAIAAMKLVAE--GRDELLILPADHVIE 115
Query: 120 VNDNYMEAFKKAEKLAEK-YLVTFGIKPTKPHTGYGYIKPGEKIKV-EGKTIGYLVDEFK 177
+ +A A AEK +V FGI ++P TGYGYI+ ++ EG + V F
Sbjct: 116 DQRAFQQALALATNAAEKGEMVLFGIPASRPETGYGYIRATADAQLPEGVS---RVQSFV 172
Query: 178 EKPDLETAKKYVE-NGYYWNSGMFMFRTSVFMEEARKHAPETV--------RAFEEGKSI 228
EKPD A+++V GYYWNSGMF+FR S ++EE +KH + R+ +G +
Sbjct: 173 EKPDEARAREFVAAGGYYWNSGMFLFRASRYLEELKKHDADIYDTCLLALERSQHDGDLV 232
Query: 229 E---EIYELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVA 285
+E P+ S+DY +MEKT +A VVPL+ WND+GS+ ++++ KD NGN
Sbjct: 233 NIDAATFECCPDNSIDYAVMEKTSRACVVPLSAGWNDVGSWSSIWDVHAKDANGNVT--- 289
Query: 286 GFKAKYININSRNNLILTE-RLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLRE 344
K + +S N L+ +L + +G+ED+++V+T DA+++A + Q VK V K L
Sbjct: 290 --KGDVLVHDSHNCLVHGNGKLVSVIGLEDIVVVETKDAMMIAHKDRVQDVKHVVKDLDA 347
Query: 345 ENDERAIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTA 404
+ H YRPWGSY ++ G R+++K ITV PG RLSLQ+H+HR+EHW+VV GTA
Sbjct: 348 QGRSETQNHCEVYRPWGSYDSVDMGGRFQVKHITVKPGARLSLQMHHHRAEHWIVVSGTA 407
Query: 405 KVVVGDKEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFGR 464
+V DK F+L +ST+IP HRL NPGK+ LE+IE Q G YLGEDDI RL+D +GR
Sbjct: 408 QVTCDDKTFLLTENQSTYIPIASVHRLANPGKIPLEIIEVQSGSYLGEDDIERLEDVYGR 467
>sp|P37753|RFM9_ECOLI MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE (GDP) (GDP-MANNOSE
PYROPHOSPHORYLASE) (GMP) >gi|2121131|pir||I84556
GDP-manno pyrophosphorylase - Escherichia coli
>gi|441139|gb|AAA21139.1| (L27632) GDP-manno
pyrophosphorylase [Escherichia coli]
Length = 471
Score = 363 bits (922), Expect = 2e-99
Identities = 202/475 (42%), Positives = 284/475 (59%), Gaps = 23/475 (4%)
Query: 4 LILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERALLFSKPKEIFIVTNKEYKFR 63
+I+AGG G+RLWP+SRE PKQF+++F S+ Q+T+ R L + E ++ N+E++F
Sbjct: 5 VIMAGGTGSRLWPMSRELYPKQFLRLFGQNSMLQETITR-LSGLEVHEPMVICNEEHRFL 63
Query: 64 VLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENYGDSVVAVLPSDHAIKVNDN 123
V + L +L NI+LEPVG+NT PAI + D ++ VL +DH I
Sbjct: 64 VAEQLRQLNKL--SSNIILEPVGRNTAPAIALAALQATRHGDDPLMLVLAADHIINNQPV 121
Query: 124 YMEAFKKAEKLAEK-YLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKEKPDL 182
+ +A + AE+ A++ +LVTFGI P P TGYGYI+ G + T Y V F EKPD
Sbjct: 122 FHDAIRVAEQYADEGHLVTFGIVPNAPETGYGYIQRGVAVTDSAHT-PYQVARFVEKPDR 180
Query: 183 ETAKKYVENG-YYWNSGMFMFRTSVFMEEARKHAPE-------TVRAFEEGKSI----EE 230
E A Y+ +G YYWNSGMFMFR ++ E K P+ V A + G +
Sbjct: 181 ERAGAYLASGEYYWNSGMFMFRAKKYLSELAKFRPDILEACQAAVNAADNGSDFISIPHD 240
Query: 231 IYELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAGFKAK 290
I+ P+ SVDY +MEKT A VV L+ W+D+GS+ A++E KD GN + +
Sbjct: 241 IFCECPDESVDYAVMEKTADAVVVGLDADWSDVGSWSALWEVSPKDGQGNVLSGDAWVH- 299
Query: 291 YININSRNNLILT-ERLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLREENDER 349
NS N I + E+L A +GVE+L+IV T DA+LV R +Q VK+ + L++
Sbjct: 300 ----NSENCYINSDEKLVAAIGVENLVIVSTKDAVLVMNRERSQDVKKAVEFLKQNQRTE 355
Query: 350 AIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAKVVVG 409
HR YRPWG V+ + R+ + RITV PG S+Q+H+HR+EHWV++ GT +V V
Sbjct: 356 YKRHREIYRPWGRCDVVVQTPRFNVNRITVKPGGAFSMQMHHHRAEHWVILAGTGQVTVN 415
Query: 410 DKEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFGR 464
K+F+L +STFIP G H LENPG + LEV+E Q G YLGEDDI+R++D +GR
Sbjct: 416 GKQFLLSENQSTFIPIGAEHCLENPGCIPLEVLEIQSGSYLGEDDIIRIKDQYGR 470
>pir||I41251 GDP-mannose pyrophosphorylase [validated] - Escherichia coli
>gi|441136|gb|AAA21137.1| (L27646) GDP-mannose
pyrophosphorylase [Escherichia coli]
Length = 471
Score = 363 bits (921), Expect = 3e-99
Identities = 202/475 (42%), Positives = 284/475 (59%), Gaps = 23/475 (4%)
Query: 4 LILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERALLFSKPKEIFIVTNKEYKFR 63
+I+AGG G+RLWP+SRE PKQF+++F S+ Q+T+ R L + E ++ N+E++F
Sbjct: 5 VIMAGGTGSRLWPMSRELYPKQFLRLFGQNSMLQETITR-LSGLEVHEPMVICNEEHRFL 63
Query: 64 VLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENYGDSVVAVLPSDHAIKVNDN 123
V + L +L NI+LEPVG+NT PAI + D ++ VL +DH I
Sbjct: 64 VAEQLRQLNKL--SSNIILEPVGRNTAPAIALAALQATRHGDDPLMLVLAADHIINNQPV 121
Query: 124 YMEAFKKAEKLAEK-YLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKEKPDL 182
+ +A + AE+ A++ +LVTFGI P P TGYGYI+ G + T Y V F EKPD
Sbjct: 122 FHDAIRVAEQYADEGHLVTFGIVPNAPETGYGYIQRGVALTDSAHT-PYQVARFVEKPDR 180
Query: 183 ETAKKYVENG-YYWNSGMFMFRTSVFMEEARKHAPE-------TVRAFEEGKSI----EE 230
E A Y+ +G YYWNSGMFMFR ++ E K P+ V A + G +
Sbjct: 181 ERAGAYLASGEYYWNSGMFMFRAKKYLSELAKFRPDILEACQAAVNAADNGSDFISIPHD 240
Query: 231 IYELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAGFKAK 290
I+ P+ SVDY +MEKT A VV L+ W+D+GS+ A++E KD GN + +
Sbjct: 241 IFCECPDESVDYAVMEKTADAVVVGLDADWSDVGSWSALWEVSPKDGQGNVLSGDAWVH- 299
Query: 291 YININSRNNLILT-ERLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLREENDER 349
NS N I + E+L A +GVE+L+IV T DA+LV R +Q VK+ + L++
Sbjct: 300 ----NSENCYINSDEKLVAAIGVENLVIVSTKDAVLVMNRERSQDVKKAVEFLKQNQRTE 355
Query: 350 AIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAKVVVG 409
HR YRPWG V+ + R+ + RITV PG S+Q+H+HR+EHWV++ GT +V V
Sbjct: 356 YKRHREIYRPWGRCDVVVQTPRFNVNRITVKPGGAFSMQMHHHRAEHWVILAGTGQVTVN 415
Query: 410 DKEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFGR 464
K+F+L +STFIP G H LENPG + LEV+E Q G YLGEDDI+R++D +GR
Sbjct: 416 GKQFLLSENQSTFIPIGAEHCLENPGCIPLEVLEIQSGSYLGEDDIIRIKDQYGR 470
>dbj|BAA28322.1| (AB010150) GDP-mannose pyrophosphorylase [Escherichia coli]
Length = 471
Score = 363 bits (921), Expect = 3e-99
Identities = 201/475 (42%), Positives = 284/475 (59%), Gaps = 23/475 (4%)
Query: 4 LILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERALLFSKPKEIFIVTNKEYKFR 63
+I+AGG G+RLWP+SRE PKQF++++ S+ Q+T+ R L + E ++ N+E++F
Sbjct: 5 VIMAGGTGSRLWPMSRELYPKQFLRLYGQNSMLQETITR-LSGLEIHEPMVICNEEHRFL 63
Query: 64 VLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENYGDSVVAVLPSDHAIKVNDN 123
V + L +L NI+LEPVG+NT PAI D ++ VL +DH I
Sbjct: 64 VAEQLRQLNKL--SNNIILEPVGRNTAPAIALAALQATRYGDDPLMLVLAADHIINNQSA 121
Query: 124 YMEAFKKAEKLAEK-YLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKEKPDL 182
+ +A + AE+ A++ +LVTFGI P P TGYGYI+ G + T Y V F EKPD
Sbjct: 122 FHDAIRVAEQYADEGHLVTFGIVPNAPETGYGYIQRGMALTDSAHT-PYQVARFVEKPDR 180
Query: 183 ETAKKYVENG-YYWNSGMFMFRTSVFMEEARKHAPE-------TVRAFEEGKSI----EE 230
+ A+ Y+ +G YYWNSGMFMFR ++ E K P+ V A + G +
Sbjct: 181 DRAEAYLASGEYYWNSGMFMFRAKKYLSELAKFRPDILEACQAAVNAADNGSDFISIPHD 240
Query: 231 IYELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAGFKAK 290
I+ P+ SVDY +MEKT A VV L+ W+D+GS+ A++E KDE GN + +
Sbjct: 241 IFCECPDESVDYAVMEKTADAVVVGLDADWSDVGSWSALWEVSPKDEQGNVLSGDAWVH- 299
Query: 291 YININSRNNLILT-ERLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLREENDER 349
NS N I + E+L A +GVE+L+IV T DA+LV R +Q VK+ + L++
Sbjct: 300 ----NSENCYINSDEKLVAAIGVENLVIVSTKDAVLVMNRERSQDVKKAVEFLKQNQRSE 355
Query: 350 AIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAKVVVG 409
HR YRPWG V+ + R+ + RITV PG S+Q+H+HR EHWV++ GT +V V
Sbjct: 356 YKRHREIYRPWGRCDVVVQTPRFNVNRITVKPGGAFSMQMHHHRVEHWVILAGTGQVTVN 415
Query: 410 DKEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFGR 464
K+F+L +STFIP G H LENPG + LEV+E Q G YLGEDDI+R++D +GR
Sbjct: 416 GKQFLLSENQSTFIPIGAEHCLENPGCIPLEVLEIQSGSYLGEDDIIRIKDQYGR 470
>sp|P55357|NOEJ_RHISN MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE (GDP) (GDP-MANNOSE
PYROPHOSPHORYLASE) (GMP) >gi|2182298|gb|AAB91607.1|
(AE000064) NoeJ [Rhizobium sp. NGR234]
Length = 512
Score = 361 bits (918), Expect = 7e-99
Identities = 200/481 (41%), Positives = 301/481 (61%), Gaps = 34/481 (7%)
Query: 5 ILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVER---ALLFSKPKEIFIVTNKEYK 61
I+AGG+GTRLWPLSR KQF+K+ + +LFQ T++R A ++ P ++TN+E++
Sbjct: 37 IMAGGRGTRLWPLSRATAAKQFLKLIGEETLFQDTLKRVSDAKVYGAP---LVITNEEFR 93
Query: 62 FRVLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENYG-DSVVAVLPSDHAIKV 120
F V + ELG+ + +I+LEPV +NT A+ +++ + +G D+++ VLPSDHAI V
Sbjct: 94 FLVAEQARELGVTL--SSIVLEPVPRNTAAAVAVAARIVADRFGEDALLLVLPSDHAITV 151
Query: 121 NDNYMEAFKKA-EKLAEKYLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKEK 179
+D Y + + A AE LVTFGI+PT P TGYGYI+ G + GK + + V F EK
Sbjct: 152 DDTYKKCVRSACIAAAEGKLVTFGIQPTWPATGYGYIERGTYL---GKDV-HAVQCFVEK 207
Query: 180 PDLETAKKYVENG-YYWNSGMFMFRTSVFMEEARKHAPET---VRAFEEGKSIE------ 229
P LE A +E G YYWNSGMF+F+ + + E +HAP+ V A G +++
Sbjct: 208 PSLEKAAALLETGNYYWNSGMFLFQAASIIAELEEHAPDVLSAVHAAVRGSTVDADFIRL 267
Query: 230 --EIYELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAGF 287
E + P IS+DY +MEKT AAVV + W+DLGS+DAV++ +++ +GN +
Sbjct: 268 APESFSQAPSISIDYALMEKTANAAVVCSDFAWSDLGSWDAVWKNEEQNADGNVL----- 322
Query: 288 KAKYININSRNNLILTERLTATV-GVEDLIIVDTGDALLVAKRGETQKVKEVYKRLR-EE 345
K N++N+L+L+ V G++ + ++ + DA+ V + E ++ + KRL +E
Sbjct: 323 KGNVTACNTKNSLVLSHTAHLAVQGMDGVAVIASEDAVFVGRLEEAHEIGNLVKRLAADE 382
Query: 346 NDERAI-VHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTA 404
N R +H T RPWG YT + G+R++++R+ V PGK LSL H+HRSEHW+ V+GTA
Sbjct: 383 NTARLTELHPTLIRPWGGYTTMLNGDRFQVRRLFVRPGKMLSLHKHFHRSEHWICVKGTA 442
Query: 405 KVVVGDKEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFGR 464
+V + D+ IL +S +IP G HRL NPGK++LE++E Q G YLGEDDI+R+ D+
Sbjct: 443 EVTIEDRVTILHENQSIYIPEGAIHRLGNPGKIMLELVEIQTGAYLGEDDIIRVADESRN 502
Query: 465 E 465
E
Sbjct: 503 E 503
>sp|P26340|MANC_SALTY MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE (GDP) (GDP-MANNOSE
PYROPHOSPHORYLASE) (GMP) >gi|96805|pir||S16290
mannose-1-phosphate guanyltransferase - Salmonella
typhimurium >gi|47655|emb|CAA42540.1| (X59886)
mannose-1-phosphate guanyltransferase [Salmonella
enterica]
Length = 480
Score = 360 bits (914), Expect = 2e-98
Identities = 193/477 (40%), Positives = 289/477 (60%), Gaps = 24/477 (5%)
Query: 4 LILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERALLFSKPKEIFIVTNKEYKFR 63
+++AGG G+RLWPLSR PKQF+ + D ++ Q T+ R L + + ++ N++++F
Sbjct: 11 VVMAGGSGSRLWPLSRVLYPKQFLCLKGDLTMLQTTICR-LNGVECESPLVICNEQHRFI 69
Query: 64 VLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENYGDS--VVAVLPSDHAIKVN 121
V + L +L ENI+LEP G+NT PAI + D ++ VL +DHAI
Sbjct: 70 VAEQLRQLNKLT--ENIILEPAGRNTAPAIALAALAATRQHTDCDPLMLVLAADHAIANE 127
Query: 122 DNYMEAFKKAEKLAEK-YLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKEKP 180
+ + +A + A A+ LVTFGI P P TGYGYI+ G+ + + + V +F EKP
Sbjct: 128 EAFRDAVRGAMPYADAGKLVTFGIVPDLPETGYGYIRRGDVVPGATDAVAFEVAQFVEKP 187
Query: 181 DLETAKKYVENG-YYWNSGMFMFRTSVFMEEARKHAPETVRAFEEG-----------KSI 228
LETA+ YV +G YYWNSGMF+FR ++EE +K P+ + A E+ +
Sbjct: 188 GLETAQAYVASGDYYWNSGMFLFRAGRYLEELKKFRPDILAACEQAMRGVDPDLDFIRVD 247
Query: 229 EEIYELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAGFK 288
EE + PE S+DY +ME+T A V+P++ W+D+GS+ +++E GN
Sbjct: 248 EEAFLACPEESIDYAVMERTADAVVMPMDAGWSDVGSWSSLWEISAHTPEGNV-----HH 302
Query: 289 AKYININSRNNLILTER-LTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLREEND 347
I+ + N+ + E L TVGV+DL++V T DA+L+A R Q VK+V ++++ +
Sbjct: 303 GDVISHKTENSYVYAESGLVTTVGVKDLVVVQTKDAVLIADRHAVQDVKKVVEKIKADGR 362
Query: 348 ERAIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAKVV 407
+HR YRPWG Y ++ GERY++KRITV PG+ LS+Q+H+HR+EHWVVV GTA+V
Sbjct: 363 HEHHMHREVYRPWGKYDSIDAGERYQVKRITVKPGEGLSVQMHHHRAEHWVVVAGTARVT 422
Query: 408 VGDKEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFGR 464
+ + +L ES +IP G H LENPGK+ L++IE + G YL EDD+VR +D +GR
Sbjct: 423 INGEVKLLGENESIYIPLGATHCLENPGKIPLDLIEVRSGSYLEEDDVVRFEDRYGR 479
>gb|AAC32348.1| (AF061251) mannose-1-P guanosyltransferase ManC [Escherichia coli]
Length = 482
Score = 359 bits (912), Expect = 3e-98
Identities = 194/483 (40%), Positives = 302/483 (62%), Gaps = 31/483 (6%)
Query: 4 LILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERALLFSKPKEIFIVTNKEYKFR 63
+++AGG G+RLWPLSRE PKQF+++ D +L Q T+ R S K + ++TN++++F
Sbjct: 9 VVMAGGTGSRLWPLSRELYPKQFLQLSGDNTLLQTTLLRLSGLSCQKPL-VITNEQHRFV 67
Query: 64 VLDDLNELGLKVPEENILLEPVGKNTLPAI----YWGLKVIDENYGDSVVAVLPSDHAIK 119
V + L E+ NI+LEP G+NT PAI + LK + D ++ VL +DH I
Sbjct: 68 VAEQLREINKL--NGNIILEPCGRNTAPAIAISAFHALKRNPQE--DPLLLVLAADHVIA 123
Query: 120 VNDNYMEAFKKAEKLAEK-YLVTFGIKPTKPHTGYGYIKPGE-KIKVEG--KTIGYLVDE 175
+ +A K A +A + +VTFGI P TGYGYI+ GE + ++G T Y V++
Sbjct: 124 KESVFCDAIKNATPIANQGKIVTFGIIPEYAETGYGYIERGELSVPLQGHENTGFYYVNK 183
Query: 176 FKEKPDLETAKKYVENG-YYWNSGMFMFRTSVFMEEARKHAPETVRAFEEGKSI------ 228
F EKP+ ETA+ Y+ +G +YWNSG+FMF+ SV++EE RK P+ E+ S
Sbjct: 184 FVEKPNRETAELYMTSGNHYWNSGIFMFKASVYLEELRKFRPDIYNVCEQVASSSYIDLD 243
Query: 229 -----EEIYELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQ 283
+E ++ P S+D+ +MEKT+K V P++ W+D+GS+ ++++ K + G+
Sbjct: 244 FIRLSKEQFQDCPAESIDFAVMEKTEKCVVCPVDIGWSDVGSWQSLWDISLKSKTGDVC- 302
Query: 284 VAGFKAKYININSRNNLILTER-LTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRL 342
K + +++NN I +E L A +G+ED++IV T DA+LV+K+ + Q VK++ + L
Sbjct: 303 ----KGDILTYDTKNNYIYSESALVAAIGIEDMVIVQTKDAVLVSKKSDVQHVKKIVEML 358
Query: 343 REENDERAIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRG 402
+ + I HR +RPWG + +++GERYK+K+I V PG+ LSL++H+HRSEHW+V+ G
Sbjct: 359 KLQQRTEYISHREVFRPWGKFDSIDQGERYKVKKIIVKPGEGLSLRMHHHRSEHWIVLSG 418
Query: 403 TAKVVVGDKEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDF 462
TAKV +GDK ++ ES +IP G + LENPG + L +IE G+YLGEDDI+R ++ +
Sbjct: 419 TAKVTLGDKTKLVTANESIYIPLGAAYSLENPGIIPLNLIEVSSGDYLGEDDIIRQKERY 478
Query: 463 GRE 465
E
Sbjct: 479 KHE 481
>dbj|BAA77733.1| (AB008676) mannose-1-phoshate guanylyltransferase [Escherichia
coli]
Length = 472
Score = 358 bits (908), Expect = 1e-97
Identities = 194/481 (40%), Positives = 300/481 (62%), Gaps = 31/481 (6%)
Query: 6 LAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERALLFSKPKEIFIVTNKEYKFRVL 65
+AGG G+RLWPLSRE PKQF+++ D +L Q T+ R S K + ++TN++++F V
Sbjct: 1 MAGGTGSRLWPLSRELYPKQFLQLSGDNTLLQTTLLRLSGLSCQKPL-VITNEQHRFVVA 59
Query: 66 DDLNELGLKVPEENILLEPVGKNTLPAI----YWGLKVIDENYGDSVVAVLPSDHAIKVN 121
+ L E+ NI+LEP G+NT PAI + LK + D ++ VL +DH I
Sbjct: 60 EQLREINKL--NGNIILEPCGRNTAPAIAISAFHALKRNPQE--DPLLLVLAADHVIAKE 115
Query: 122 DNYMEAFKKAEKLAEK-YLVTFGIKPTKPHTGYGYIKPGE-KIKVEG--KTIGYLVDEFK 177
+ +A K A +A + +VTFGI P TGYGYI+ GE + ++G T Y V++F
Sbjct: 116 SVFCDAIKNATPIANQGKIVTFGIIPEYAETGYGYIERGELSVPLQGHENTGFYYVNKFV 175
Query: 178 EKPDLETAKKYVENG-YYWNSGMFMFRTSVFMEEARKHAPETVRAFEEGKSI-------- 228
EKP+ ETA+ Y+ +G +YWNSG+FMF+ SV++EE RK P+ E+ S
Sbjct: 176 EKPNRETAELYMTSGNHYWNSGIFMFKASVYLEELRKFRPDIYNVCEQVASSSYIDLDFI 235
Query: 229 ---EEIYELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVA 285
+E ++ P S+D+ +MEKT+K V P++ W+D+GS+ ++++ K + G+
Sbjct: 236 RLSKEQFQDCPAESIDFAVMEKTEKCVVCPVDIGWSDVGSWQSLWDISLKSKTGDVC--- 292
Query: 286 GFKAKYININSRNNLILTER-LTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLRE 344
K + +++NN I +E L A +G+ED++IV T DA+LV+K+ + Q VK++ + L+
Sbjct: 293 --KGDILTYDTKNNYIYSESALVAAIGIEDMVIVQTKDAVLVSKKSDVQHVKKIVEMLKL 350
Query: 345 ENDERAIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTA 404
+ I HR +RPWG + +++GERYK+K+I V PG+ LSL++H+HRSEHW+V+ GTA
Sbjct: 351 QQRTEYISHREVFRPWGKFDSIDQGERYKVKKIIVKPGEGLSLRMHHHRSEHWIVLSGTA 410
Query: 405 KVVVGDKEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFGR 464
KV +GDK ++ ES +IP G + LENPG + L +IE G+YLGEDDI+R ++ +
Sbjct: 411 KVTLGDKTKLVTANESIYIPLGAAYSLENPGIIPLNLIEVSSGDYLGEDDIIRQKERYKH 470
Query: 465 E 465
E
Sbjct: 471 E 471
>dbj|BAA02175.1| (D12652) pssM protein [Rhodospirillum rubrum]
Length = 494
Score = 351 bits (890), Expect = 1e-95
Identities = 197/481 (40%), Positives = 283/481 (57%), Gaps = 36/481 (7%)
Query: 4 LILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERAL--LFSKPKEIFIVTNKEYK 61
+IL+GG G+RLWPLSR PKQF+ + S+ ++ Q+T RA F+ P ++ N E++
Sbjct: 13 VILSGGSGSRLWPLSRALYPKQFLPLVSELTMIQETALRASGERFTAP---LVICNDEHR 69
Query: 62 FRVLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENYGDSVVAVLPSDHAIKVN 121
F V + L + I+LEPVG+NT PA+ + E+ D ++ V+PSDH I+
Sbjct: 70 FIVAEQLRAAACQPTA--IILEPVGRNTAPAVAVAALKLLESASDPIMLVMPSDHVIQNA 127
Query: 122 DNYMEAFKKAEKLAEK-YLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYL-VDEFKEK 179
D ++ A +A A LVTFGI P P TGYGYIK G G L V+ F EK
Sbjct: 128 DAFLAAIDQAAPAARAGALVTFGITPNAPETGYGYIKAGGSF---APFTGVLRVERFVEK 184
Query: 180 PDLETAKKYVENG-YYWNSGMFMFRTSVFMEEARKHAPETVRAFEEGKSIEE-------- 230
P+L+TA+ Y+ G Y WNSG+F+F ++ E + + + A + + +
Sbjct: 185 PNLQTAESYLAEGSYLWNSGIFLFSAKAYLAELGRTNSKIIEACSQALAQGQRDLSFCRL 244
Query: 231 ---IYELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNA----VQ 283
+ P S+DY +MEKT AAV P+ W+DLG++ A++E KD N V
Sbjct: 245 DAAAFAASPADSIDYAVMEKTANAAVFPVEMGWSDLGAWSALWEIGPKDAQDNVALGDVL 304
Query: 284 VAGFKAKYININSRNNLILTERLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLR 343
+ + YI + RL A G+ ++++V T DA+LV RG+ Q VK++ +RL+
Sbjct: 305 LQDVEGSYIRSD--------HRLVAVAGLCNVVVVATDDAVLVIDRGKVQDVKQIVERLK 356
Query: 344 EENDERAIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGT 403
+ N + +H T +RPWG Y ++ GER+++KRI V PG+RLSLQ+H+HR+EHW+VV GT
Sbjct: 357 KANRDEHALHSTVHRPWGHYRGIDRGERFQVKRIVVQPGERLSLQMHHHRAEHWIVVTGT 416
Query: 404 AKVVVGDKEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFG 463
A V G + F+L EST+I AG HRLENPGKV L +IE Q G YLGEDDIVR +D +G
Sbjct: 417 ALVTRGAETFLLHENESTYIRAGQTHRLENPGKVPLHLIEVQSGGYLGEDDIVRFEDGYG 476
Query: 464 R 464
R
Sbjct: 477 R 477
>pir||S30187 mannose-6-phosphate isomerase (EC 5.3.1.8) / mannose-1-phosphate
guanyltransferase - Rhodospirillum rubrum
Length = 494
Score = 351 bits (890), Expect = 1e-95
Identities = 197/481 (40%), Positives = 283/481 (57%), Gaps = 36/481 (7%)
Query: 4 LILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERAL--LFSKPKEIFIVTNKEYK 61
+IL+GG G+RLWPLSR PKQF+ + S+ ++ Q+T RA F+ P ++ N E++
Sbjct: 13 VILSGGSGSRLWPLSRALYPKQFLPLVSELTMIQETALRASGERFTAP---LVICNDEHR 69
Query: 62 FRVLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENYGDSVVAVLPSDHAIKVN 121
F V + L + I+LEPVG+NT PA+ + E+ D ++ V+PSDH I+
Sbjct: 70 FIVAEQLRAAACQPTA--IILEPVGRNTAPAVAVAALKLLESASDPIMLVMPSDHVIQNA 127
Query: 122 DNYMEAFKKAEKLAEK-YLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYL-VDEFKEK 179
D ++ A +A A LVTFGI P P TGYGYIK G G L V+ F EK
Sbjct: 128 DAFLAAIDQAPPAARAGALVTFGITPNAPETGYGYIKAGGSF---APFTGVLRVERFVEK 184
Query: 180 PDLETAKKYVENG-YYWNSGMFMFRTSVFMEEARKHAPETVRAFEEGKSIEE-------- 230
P+L+TA+ Y+ G Y WNSG+F+F ++ E + + + A + + +
Sbjct: 185 PNLQTAESYLAEGSYLWNSGIFLFSAKAYLAELGRTNSKIIEACSQALAQGQRDLSFCRL 244
Query: 231 ---IYELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNA----VQ 283
+ P S+DY +MEKT AAV P+ W+DLG++ A++E KD N V
Sbjct: 245 DAAAFAASPADSIDYAVMEKTANAAVFPVEMGWSDLGAWSALWEIGPKDAQDNVALGDVL 304
Query: 284 VAGFKAKYININSRNNLILTERLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLR 343
+ + YI + RL A G+ ++++V T DA+LV RG+ Q VK++ +RL+
Sbjct: 305 LQDVEGSYIRSD--------HRLVAVAGLCNVVVVATDDAVLVIDRGKVQDVKQIVERLK 356
Query: 344 EENDERAIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGT 403
+ N + +H T +RPWG Y ++ GER+++KRI V PG+RLSLQ+H+HR+EHW+VV GT
Sbjct: 357 KANRDEHALHSTVHRPWGHYRGIDRGERFQVKRIVVQPGERLSLQMHHHRAEHWIVVTGT 416
Query: 404 AKVVVGDKEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFG 463
A V G + F+L EST+I AG HRLENPGKV L +IE Q G YLGEDDIVR +D +G
Sbjct: 417 ALVTRGAETFLLHENESTYIRAGQTHRLENPGKVPLHLIEVQSGGYLGEDDIVRFEDGYG 476
Query: 464 R 464
R
Sbjct: 477 R 477
>sp|Q00473|RFBM_SALMU MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE (GDP) (GDP-MANNOSE
PYROPHOSPHORYLASE) (GMP) >gi|96676|pir||S22621
phosphomannomutase - Salmonella choleraesuis
>gi|47013|emb|CAA43915.1| (X61917) mannose-1-phosphate
guanyltransferase [Salmonella enterica]
Length = 473
Score = 349 bits (886), Expect = 4e-95
Identities = 197/481 (40%), Positives = 284/481 (58%), Gaps = 38/481 (7%)
Query: 4 LILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERA--LLFSKPKEIFIVTNKEYK 61
+I+AGG G+RLWPLSRE PKQF+ V + S+ Q T++R LL +P ++ N ++
Sbjct: 7 VIMAGGIGSRLWPLSREEHPKQFLSVDGELSMLQNTIKRLTPLLAGEP---LVICNDSHR 63
Query: 62 FRVLDDLNELGLKVPEENILLEPVGKNTLPAIYWGL-----KVIDENYGDSVVAVLPSDH 116
F V + L + NI+LEPVG+NT PAI V+DE D ++ VL +DH
Sbjct: 64 FLVAEQLRAINKLA--NNIILEPVGRNTAPAIALAAFCSLQNVVDE---DPLLLVLAADH 118
Query: 117 AIKVNDNYMEAFKKAEKLAEK-YLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDE 175
I+ +++A AE A + LVTFGI PT+ TGYGYI GE I + + V E
Sbjct: 119 VIRDEKVFLKAINHAEFFATQGKLVTFGIVPTQAETGYGYICRGEAIGEDA----FSVAE 174
Query: 176 FKEKPDLETAKKYVENG-YYWNSGMFMFRTSVFMEEARKHAPETVRAFEEG--------- 225
F EKPD +TA+ YVE+ YYWNSGMF+FR S +++E + +P+ +A E
Sbjct: 175 FVEKPDFDTARHYVESEKYYWNSGMFLFRASSYLQELKDLSPDIYQACENAVGSINPDLD 234
Query: 226 --KSIEEIYELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQ 283
+ +E + + P S+DY +ME T A VVP+N W+D+GS+ ++++ KD N +
Sbjct: 235 FIRIDKEAFAMCPSDSIDYAVMEHTRHAVVVPMNAGWSDVGSWSSLWDISKKDPQRNVLH 294
Query: 284 VAGFKAKYININSRNNLILTER-LTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRL 342
F NS++N I +E+ +T+GV +L+IV T DALLV+ + Q VK+V L
Sbjct: 295 GDIFA-----YNSKDNYIYSEKSFISTIGVNNLVIVQTADALLVSDKDSVQDVKKVVDYL 349
Query: 343 REENDERAIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRG 402
+ N H +RPWG ++V+ G+ Y +KRITV PG + + Q+H HR+EHW+VV G
Sbjct: 350 KANNRNEHKKHLEVFRPWGKFSVIHSGDNYLVKRITVKPGAKFAAQMHLHRAEHWIVVSG 409
Query: 403 TAKVVVGDKEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDF 462
TA + G++ F + ESTFIPA H L+NP + LE+IE Q G YL EDDI+RL+
Sbjct: 410 TACITKGEEIFTISENESTFIPANTVHTLKNPATIPLELIEIQSGTYLAEDDIIRLEKHS 469
Query: 463 G 463
G
Sbjct: 470 G 470
>gb|AAC44882.1| (AF078736) mannose-1-phosphate guanylyltransferase [Escherichia
coli]
Length = 483
Score = 348 bits (883), Expect = 9e-95
Identities = 189/475 (39%), Positives = 283/475 (58%), Gaps = 24/475 (5%)
Query: 4 LILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERALLFSKPKEIFIVTNKEYKFR 63
+I+AGG G+RLWPLSR PKQF+ + D ++ Q T+ R L + + ++ N++++F
Sbjct: 8 VIIAGGTGSRLWPLSRVLYPKQFLNLVGDSTMLQTTITR-LDGIECENPIVICNEDHRFI 66
Query: 64 VLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENY--GDSVVAVLPSDHAIKVN 121
V + L ++G +NI+LEP G+NT PAI + +N D ++ VL +DH+I
Sbjct: 67 VAEQLRQIGKLT--KNIILEPKGRNTAPAIALAAFIAQKNNPNDDPLLLVLAADHSINNE 124
Query: 122 DNYMEAFKKAEKLAEK-YLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKEKP 180
+ E+ KA A LVTFGI P +TGYGYIK + Y V EF EKP
Sbjct: 125 KAFRESIIKAMPYATSGKLVTFGIIPDTANTGYGYIKRSSSADPNKEFPAYNVAEFVEKP 184
Query: 181 DLETAKKYVENG-YYWNSGMFMFRTSVFMEEARKHAPETVRAFEEGKSIEEI-------- 231
D++TA++Y+ +G YYWNSGMF+FR S +++E RK P+ + E + I
Sbjct: 185 DVKTAQEYISSGNYYWNSGMFLFRASKYLDELRKFRPDIYHSCECATATANIDMDFVRIN 244
Query: 232 ---YELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAGFK 288
+ PE S+DY +MEKT A V+P++ WND+GS+ ++++ KD +GN
Sbjct: 245 EAEFINCPEESIDYAVMEKTKDAVVLPIDIGWNDVGSWSSLWDISQKDCHGNVCH----- 299
Query: 289 AKYININSRNNLILTER-LTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLREEND 347
+N + N+ I +E L ATVGV +L+IV T DA+LVA R + Q VK + L++
Sbjct: 300 GDVLNHDGENSFIYSESSLVATVGVSNLVIVQTKDAVLVADRDKVQNVKNIVDDLKKRKR 359
Query: 348 ERAIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAKVV 407
+HR +RPWG + +++G+RY++K+I V PG+ L L++H+HR+EHW+VV GTAKV
Sbjct: 360 AEYYMHRAVFRPWGKFDAIDQGDRYRVKKIIVKPGEGLDLRMHHHRAEHWIVVSGTAKVS 419
Query: 408 VGDKEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDF 462
+G + +L ES +IP G + LENPG + L +IE G+YL DDIVR D +
Sbjct: 420 LGSEVKLLVSNESIYIPQGAKYSLENPGVIPLHLIEVSSGDYLESDDIVRFTDRY 474
>gb|AAF04378.1|AF189151_1 (AF189151) ManC; GDP-mannose pyrophosphorylase [Klebsiella
pneumoniae]
Length = 454
Score = 346 bits (879), Expect = 3e-94
Identities = 193/462 (41%), Positives = 275/462 (58%), Gaps = 23/462 (4%)
Query: 17 LSREAMPKQFIKVFSDRSLFQKTVERALLFSKPKEIFIVTNKEYKFRVLDDLNELGLKVP 76
+SRE PKQF++++ S+ Q+T+ R L + E ++ N+E++F V + L +L
Sbjct: 1 MSRELYPKQFLRLYGQNSMLQETITR-LSGLEIHEPMVICNEEHRFLVAEQLRQLNKL-- 57
Query: 77 EENILLEPVGKNTLPAIYWGLKVIDENYGDSVVAVLPSDHAIKVNDNYMEAFKKAEKLAE 136
NI+LEPVG+NT PAI + D ++ VL +DH I + +A + AE+ A+
Sbjct: 58 SNNIILEPVGRNTAPAIALAALQATRHGDDPLMLVLAADHIINNQPVFHDAIRVAEQYAD 117
Query: 137 K-YLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKEKPDLETAKKYVENG-YY 194
+ +LVTFGI P P TGYGYI+ G + T Y V F EKPD E A+ Y+ +G YY
Sbjct: 118 EGHLVTFGIVPNAPETGYGYIQRGVALTDSAHT-PYQVARFVEKPDRERAEAYLASGEYY 176
Query: 195 WNSGMFMFRTSVFMEEARKHAPE-------TVRAFEEGKSI----EEIYELVPEISVDYG 243
WNSGMFMFR ++ E K P+ V A + G +I+ P+ SVDY
Sbjct: 177 WNSGMFMFRAKKYLSELAKFRPDILEACQAAVNAADNGSDFISIPHDIFCECPDESVDYA 236
Query: 244 IMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAGFKAKYININSRNNLILT 303
+MEKT A VV L+ W+D+GS+ A++E KDE GN + + NS N I +
Sbjct: 237 VMEKTADAVVVGLDADWSDVGSWSALWEVSPKDEQGNVLSGDAWVH-----NSENCYINS 291
Query: 304 -ERLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLREENDERAIVHRTAYRPWGS 362
E+L A +GVE+L+IV T DA+LV R +Q VK+ + L++ HR YRPWG
Sbjct: 292 DEKLVAAIGVENLVIVSTKDAVLVMNRERSQDVKKAVEFLKQNQRSEYKRHREIYRPWGR 351
Query: 363 YTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAKVVVGDKEFILRPGESTF 422
V+ + R+ + RITV PG S+Q+H+HR+EHWV++ GT +V V K+F+L +STF
Sbjct: 352 CDVVVQTPRFNVNRITVKPGGAFSMQMHHHRAEHWVILAGTGQVTVNGKQFLLTENQSTF 411
Query: 423 IPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFGR 464
IP G H LENPG++ LEV+E Q G YLGEDDI+R++D +GR
Sbjct: 412 IPIGAEHSLENPGRIPLEVLEIQSGSYLGEDDIIRIKDQYGR 453
>prf||2123305B rfbM gene [Escherichia coli]
Length = 483
Score = 345 bits (876), Expect = 6e-94
Identities = 188/475 (39%), Positives = 282/475 (58%), Gaps = 24/475 (5%)
Query: 4 LILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERALLFSKPKEIFIVTNKEYKFR 63
+I+AGG G+RLWPLS PKQF+ + D ++ Q T+ R L + + ++ N++++F
Sbjct: 8 VIIAGGTGSRLWPLSPVLYPKQFLNLVGDSTMLQTTITR-LDGIECENPIVICNEDHRFI 66
Query: 64 VLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENY--GDSVVAVLPSDHAIKVN 121
V + L ++G +NI+LEP G+NT PAI + +N D ++ VL +DH+I
Sbjct: 67 VAEQLRQIGKLT--KNIILEPKGRNTAPAIALAAFIAQKNNPNDDPLLLVLAADHSINNE 124
Query: 122 DNYMEAFKKAEKLAEK-YLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKEKP 180
+ E+ KA A LVTFGI P +TGYGYIK + Y V EF EKP
Sbjct: 125 KAFRESIIKAMPYATSGKLVTFGIIPDTANTGYGYIKRSSSADPNKEFPAYNVAEFVEKP 184
Query: 181 DLETAKKYVENG-YYWNSGMFMFRTSVFMEEARKHAPETVRAFEEGKSIEEI-------- 231
D++TA++Y+ +G YYWNSGMF+FR S +++E RK P+ + E + I
Sbjct: 185 DVKTAQEYISSGNYYWNSGMFLFRASKYLDELRKFRPDIYHSCECATATANIDMDFVRIN 244
Query: 232 ---YELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAGFK 288
+ PE S+DY +MEKT A V+P++ WND+GS+ ++++ KD +GN
Sbjct: 245 EAEFINCPEESIDYAVMEKTKDAVVLPIDIGWNDVGSWSSLWDISQKDCHGNVCH----- 299
Query: 289 AKYININSRNNLILTER-LTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLREEND 347
+N + N+ I +E L ATVGV +L+IV T DA+LVA R + Q VK + L++
Sbjct: 300 GDVLNHDGENSFIYSESSLVATVGVSNLVIVQTKDAVLVADRDKVQNVKNIVDDLKKRKR 359
Query: 348 ERAIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAKVV 407
+HR +RPWG + +++G+RY++K+I V PG+ L L++H+HR+EHW+VV GTAKV
Sbjct: 360 AEYYMHRAVFRPWGKFDAIDQGDRYRVKKIIVKPGEGLDLRMHHHRAEHWIVVSGTAKVS 419
Query: 408 VGDKEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDF 462
+G + +L ES +IP G + LENPG + L +IE G+YL DDIVR D +
Sbjct: 420 LGSEVKLLVSNESIYIPQGAKYSLENPGVIPLHLIEVSSGDYLESDDIVRFTDRY 474
>dbj|BAA28337.1| (AB010295) GDP-mannose pyrophosphorylase [Klebsiella pneumoniae]
>gi|3142232|dbj|BAA28341.1| (AB010296) GDP-mannose
pyrophosphorylase [Klebsiella pneumoniae]
Length = 452
Score = 344 bits (873), Expect = 1e-93
Identities = 192/460 (41%), Positives = 273/460 (58%), Gaps = 23/460 (5%)
Query: 19 REAMPKQFIKVFSDRSLFQKTVERALLFSKPKEIFIVTNKEYKFRVLDDLNELGLKVPEE 78
RE PKQF++++ S+ Q+T+ R L + E ++ N+E++F V + L +L
Sbjct: 1 RELYPKQFLRLYGQNSMLQETITR-LSGLEIHEPMVICNEEHRFLVAEQLRQLNKL--SN 57
Query: 79 NILLEPVGKNTLPAIYWGLKVIDENYGDSVVAVLPSDHAIKVNDNYMEAFKKAEKLAEK- 137
NI+LEPVG+NT PAI + D ++ VL +DH I + +A + AE+ A++
Sbjct: 58 NIILEPVGRNTAPAIALAALQATRHGDDPLMLVLAADHIINNQPVFHDAIRVAEQYADEG 117
Query: 138 YLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKEKPDLETAKKYVENG-YYWN 196
+LVTFGI P P TGYGYI+ G + T Y V F EKPD E A+ Y+ +G YYWN
Sbjct: 118 HLVTFGIVPNAPETGYGYIQRGVALTDSAHT-PYQVARFVEKPDRERAEAYLASGEYYWN 176
Query: 197 SGMFMFRTSVFMEEARKHAPE-------TVRAFEEGKSI----EEIYELVPEISVDYGIM 245
SGMFMFR ++ E K P+ V A + G +I+ P+ SVDY +M
Sbjct: 177 SGMFMFRAKKYLSELAKFRPDILEACQAAVNAADNGSDFISIPHDIFCECPDESVDYAVM 236
Query: 246 EKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAGFKAKYININSRNNLILT-E 304
EKT A VV L+ W+D+GS+ A++E KDE GN + + NS N I + E
Sbjct: 237 EKTADAVVVGLDADWSDVGSWSALWEVSPKDEQGNVLSGDAWVH-----NSENCYINSDE 291
Query: 305 RLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLREENDERAIVHRTAYRPWGSYT 364
+L A +GVE+L+IV T DA+LV R +Q VK+ + L++ HR YRPWG
Sbjct: 292 KLVAAIGVENLVIVSTKDAVLVMNRERSQDVKKAVEFLKQNQRSEYKRHREIYRPWGRCD 351
Query: 365 VLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAKVVVGDKEFILRPGESTFIP 424
V+ + R+ + RITV PG S+Q+H+HR+EHWV++ GT +V V K+F+L +STFIP
Sbjct: 352 VVVQTPRFNVNRITVKPGGAFSMQMHHHRAEHWVILAGTGQVTVNGKQFLLTENQSTFIP 411
Query: 425 AGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFGR 464
G H LENPG++ LEV+E Q G YLGEDDI+R++D +GR
Sbjct: 412 IGAEHSLENPGRIPLEVLEIQSGSYLGEDDIIRIKDQYGR 451
>pir||C71981 phosphomannose isomerase/gdp-mannose pyrophosphorylase -
Helicobacter pylori (strain J99)
>gi|4154546|gb|AAD05624.1| (AE001443) phosphomannose
isomerase/GDP-mannose pyrophosphorylase [Helicobacter
pylori J99]
Length = 470
Score = 344 bits (872), Expect = 2e-93
Identities = 197/482 (40%), Positives = 286/482 (58%), Gaps = 35/482 (7%)
Query: 1 MKTLILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERALLFSKPKEIFIVTNKEY 60
+K ++L+GG G RLWPLSR PKQF+K+F +SLF+ + +R S E IV N+++
Sbjct: 3 IKNVLLSGGSGKRLWPLSRSLYPKQFLKLFDHKSLFELSFKRNA--SLVDETLIVCNEKH 60
Query: 61 KFRVLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENYGDSVVAVLPSDHAIKV 120
F L+++ +K LLE + KNT AI + D+ + ++ V PSDH IK
Sbjct: 61 YFLALEEIKN-EIKNKSVGFLLESLSKNTANAIALSALMSDK---EDLLIVTPSDHLIKD 116
Query: 121 NDNYMEAFKKAEKLAEK-YLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKEK 179
Y A KKA LA+K +LVTFGI KP+T +GYI+ + V+ F EK
Sbjct: 117 FQAYENAIKKAINLAQKGFLVTFGISIEKPNTEFGYIESPNGLDVK---------RFIEK 167
Query: 180 PDLETAKKYVENG-YYWNSGMFMFRTSVFMEEARKHAPETV----RAFEE---------- 224
P LE A ++ ++G +Y+NSGMF+F+ VF++E +KHAP + RAFE
Sbjct: 168 PSLEKAIEFQKSGGFYFNSGMFVFQAGVFLDELKKHAPTILKGCERAFESLENTHFFEQK 227
Query: 225 -GKSIEEIYELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQ 283
+ E+ + + ++S+D +M+++ K +V LN W+DLG+F+A++E + NG
Sbjct: 228 IARLSEKSMQDLEDMSIDIALMQQSHKIKMVELNAKWSDLGNFNALFE---EAANGTKEN 284
Query: 284 VAGFKAKYININSRNNLILTERLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLR 343
V+ + S NNL+ + +++A +GVEDL I+DT DALLVA + + + +K + +
Sbjct: 285 VSLNQTPIFAKESTNNLVFSHKVSALLGVEDLAIIDTKDALLVAHKDKAKDLKALVSEIE 344
Query: 344 EENDERAIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGT 403
N E H YRPWGSY VL E YK+K + V P RLSLQ H+HRSEHWVV+ G
Sbjct: 345 THNQELLQTHTKVYRPWGSYEVLHESGCYKVKILEVKPNARLSLQKHFHRSEHWVVISGM 404
Query: 404 AKVVVGDKEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFG 463
A V + + F L+ EST+IP HRL N GK+ L +IE Q+GEY+GEDDIVR+ DDF
Sbjct: 405 ASVELDHQSFELQANESTYIPKNTLHRLANYGKIPLIIIEVQVGEYVGEDDIVRVDDDFN 464
Query: 464 RE 465
R+
Sbjct: 465 RQ 466
>dbj|BAA28333.1| (AB010294) GDP-mannose pyrophosphorylase [Escherichia coli]
Length = 452
Score = 341 bits (866), Expect = 8e-93
Identities = 192/460 (41%), Positives = 272/460 (58%), Gaps = 23/460 (5%)
Query: 19 REAMPKQFIKVFSDRSLFQKTVERALLFSKPKEIFIVTNKEYKFRVLDDLNELGLKVPEE 78
RE PKQF+++F S+ Q+T+ R L + E ++ N+E++F V + L +L
Sbjct: 1 RELYPKQFLRLFGQNSMLQETITR-LSGLEIHEPMVICNEEHRFLVAEQLRQLNKL--SN 57
Query: 79 NILLEPVGKNTLPAIYWGLKVIDENYGDSVVAVLPSDHAIKVNDNYMEAFKKAEKLAEK- 137
NI+LEPVG+NT PAI D ++ VL +DH I + +A + AE+ A++
Sbjct: 58 NIILEPVGRNTAPAIALAALQATRYGDDPLMLVLAADHIINNQPAFHDAIRVAEQYADEG 117
Query: 138 YLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKEKPDLETAKKYVENG-YYWN 196
+LVTFGI P P TGYGYI+ G + + Y V F EKPD E A+ Y+ +G YYWN
Sbjct: 118 HLVTFGIVPNAPETGYGYIQRGVALSNSAHS-AYQVARFVEKPDRERAEAYLSSGEYYWN 176
Query: 197 SGMFMFRTSVFMEEARKHAPE-------TVRAFEEGKSI----EEIYELVPEISVDYGIM 245
SGMFMFR ++ E K+ P+ V A + G +I+ P+ SVDY +M
Sbjct: 177 SGMFMFRAKKYLIELAKYRPDILETCQAAVNAADNGSDFINIPHDIFCECPDESVDYAVM 236
Query: 246 EKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAGFKAKYININSRNNLILT-E 304
EKT A VV L+ W+D+GS+ A++E KDE GN + + NS N I + E
Sbjct: 237 EKTADAVVVGLDADWSDVGSWSALWEVSPKDEQGNVLSGDAWVH-----NSENCYINSDE 291
Query: 305 RLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLREENDERAIVHRTAYRPWGSYT 364
+L A +GVE+L+IV T DA+LV R +Q VK+ + L++ HR YRPWG
Sbjct: 292 KLVAAIGVENLVIVSTKDAVLVMNRERSQDVKKAVEFLKQNQRSEYKRHREIYRPWGRCD 351
Query: 365 VLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAKVVVGDKEFILRPGESTFIP 424
V+ + R+ + RITV PG S+Q+H+HR+EHWV++ GT +V V K+F+L +STFIP
Sbjct: 352 VVVQTPRFNVNRITVKPGGAFSMQMHHHRAEHWVILAGTGQVTVNGKQFLLSENQSTFIP 411
Query: 425 AGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFGR 464
G H LENPG + LEV+E Q G YLGEDDI+R++D +GR
Sbjct: 412 IGAEHCLENPGCIPLEVLEIQSGAYLGEDDIIRIKDQYGR 451
>sp|P26404|RFBM_SALTY MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE (GDP) (GDP-MANNOSE
PYROPHOSPHORYLASE) (GMP) >gi|96845|pir||S15312 rfbM
protein - Salmonella typhimurium
>gi|47902|emb|CAA40128.1| (X56793) mannose-1-phosphate
guanylyltransferase (GDP) [Salmonella enterica]
Length = 479
Score = 341 bits (865), Expect = 1e-92
Identities = 189/478 (39%), Positives = 282/478 (58%), Gaps = 32/478 (6%)
Query: 4 LILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERALLFSKPKEIFIVTNKEYKFR 63
+I+AGG G+RLWPLSRE PKQF+ V S+ Q T++R S + + ++ N ++F
Sbjct: 6 VIMAGGTGSRLWPLSREYHPKQFLSVEGKLSMLQNTIKRLASLSTEEPV-VICNDRHRFL 64
Query: 64 VLDDLNELGLKVPEENILLEPVGKNTLPAI----YWGLKVIDENYGDSVVAVLPSDHAIK 119
V + L E+ NI+LEPVG+NT PAI + L+ D D ++ VL +DH I+
Sbjct: 65 VAEQLREIDKLA--NNIILEPVGRNTAPAIALAAFCALQNADN--ADPLLLVLAADHVIQ 120
Query: 120 VNDNYMEAFKKAEKLAEK-YLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKE 178
+ +A + AE+ A LVTFGI PT TGYGYI+ GE I + Y V EF E
Sbjct: 121 DEIAFTKAVRHAEEYAANGKLVTFGIVPTHAETGYGYIRRGELIGNDA----YAVAEFVE 176
Query: 179 KPDLETAKKYVENG-YYWNSGMFMFRTSVFMEEARKHAPETVRAFEEG-----------K 226
KPD++TA Y ++G YYWNSGMF+FR S ++ E + +PE +A E+ +
Sbjct: 177 KPDIDTAGDYFKSGKYYWNSGMFLFRASSYLNELKYLSPEIYKACEKAVGHINPDLDFIR 236
Query: 227 SIEEIYELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAG 286
+E + P S+DY +ME T A V+P++ W+D+GS+ ++++ +KD N +
Sbjct: 237 IDKEEFMSCPSDSIDYAVMEHTQHAVVIPMSAGWSDVGSWSSLWDISNKDHQRNVL---- 292
Query: 287 FKAKYININSRNNLILTERL-TATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLREE 345
K +N I +E + + +GV +L+IV T DALLVA + Q VK++ L+
Sbjct: 293 -KGDIFAHACNDNYIYSEDMFISAIGVSNLVIVQTTDALLVANKDTVQDVKKIVDYLKRN 351
Query: 346 NDERAIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAK 405
+ H+ +RPWG Y V++ G+ Y ++ ITV PG++ Q+H+HR+EHW+V+ GTA+
Sbjct: 352 DRNEYKQHQEVFRPWGKYNVIDSGKNYLVRCITVKPGEKFVAQMHHHRAEHWIVLSGTAR 411
Query: 406 VVVGDKEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFG 463
V G++ +++ ESTFIP H LENPG L++IE Q G YLGEDDI+RL+ G
Sbjct: 412 VTKGEQTYMVSENESTFIPPNTIHALENPGMTPLKLIEIQSGTYLGEDDIIRLEQRSG 469
>dbj|BAA28329.1| (AB010293) GDP-mannose pyrophosphorylase [Escherichia coli]
Length = 452
Score = 340 bits (863), Expect = 2e-92
Identities = 191/460 (41%), Positives = 270/460 (58%), Gaps = 23/460 (5%)
Query: 19 REAMPKQFIKVFSDRSLFQKTVERALLFSKPKEIFIVTNKEYKFRVLDDLNELGLKVPEE 78
RE PKQF+++F S+ Q+T+ R L + E ++ N+E++F V + L +L
Sbjct: 1 RELYPKQFLRLFGQNSMLQETITR-LSGLEIHEPMVICNEEHRFLVAEQLRQLNKL--SN 57
Query: 79 NILLEPVGKNTLPAIYWGLKVIDENYGDSVVAVLPSDHAIKVNDNYMEAFKKAEKLAEK- 137
NI+LEPVG+NT PAI D ++ VL +DH I + +A + AE+ A++
Sbjct: 58 NIILEPVGRNTAPAIALAALQATRYGDDPLMLVLAADHIINNQSAFHDAIRVAEQYADEG 117
Query: 138 YLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKEKPDLETAKKYVENG-YYWN 196
+LVTFGI P P TGYGYI+ G + + Y V F EKPD E A+ Y+ +G YYWN
Sbjct: 118 HLVTFGIVPNAPETGYGYIQRGVAL-TDSAHAPYQVARFVEKPDRERAEVYLASGEYYWN 176
Query: 197 SGMFMFRTSVFMEEARKHAPE-------TVRAFEEGKSI----EEIYELVPEISVDYGIM 245
SGMFMFR ++ E K P+ V A + G +I+ P+ SVDY +M
Sbjct: 177 SGMFMFRAKKYLSELAKFRPDILEACQAAVNAADNGSDFISIPHDIFCECPDESVDYAVM 236
Query: 246 EKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAGFKAKYININSRNNLILT-E 304
EKT A VV L+ W+D+GS+ A++E KD GN + + NS N I + E
Sbjct: 237 EKTADAVVVGLDADWSDVGSWSALWEVSPKDGQGNVLSGDAWVH-----NSENCYINSDE 291
Query: 305 RLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLREENDERAIVHRTAYRPWGSYT 364
+L A +GVE+L+IV T DA+LV R +Q VK+ + L++ HR YRPWG
Sbjct: 292 KLVAAIGVENLVIVSTKDAVLVMNRERSQDVKKAVEFLKQNQRSEYKRHREIYRPWGRCD 351
Query: 365 VLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAKVVVGDKEFILRPGESTFIP 424
V+ + R+ + RITV PG S+Q+H+HR+EHWV++ GT V V K+F+L +STFIP
Sbjct: 352 VVVQTPRFNVNRITVKPGGAFSMQMHHHRAEHWVILAGTGHVTVNGKQFLLTENQSTFIP 411
Query: 425 AGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFGR 464
G H LENPG++ LEV+E Q G YLGEDDI+R++D +GR
Sbjct: 412 IGAEHSLENPGRIPLEVLEIQSGSYLGEDDIIRIKDQYGR 451
>pir||C64525 mannose-6-phosphate isomerase - Helicobacter pylori (strain 26695)
>gi|2313118|gb|AAD07111.1| (AE000526)
mannose-6-phosphate isomerase (pmi) or (algA)
[Helicobacter pylori 26695]
Length = 470
Score = 339 bits (859), Expect = 6e-92
Identities = 193/484 (39%), Positives = 288/484 (58%), Gaps = 39/484 (8%)
Query: 1 MKTLILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERALLFSKPKEIFIVTNKEY 60
+K ++L+GG G RLWPLSR PKQF+K+F +SLF+ + +R S E IV N+++
Sbjct: 3 IKNILLSGGSGKRLWPLSRSLYPKQFLKLFDHKSLFELSFKRNA--SLVDETLIVCNEKH 60
Query: 61 KFRVLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENYGDSVVAVLPSDHAIKV 120
F L+++ +K LLE + KNT AI + D+ + ++ V PSDH IK
Sbjct: 61 YFLALEEIKN-EIKNKSVGFLLESLSKNTANAIALSALMSDK---EDLLIVTPSDHLIKD 116
Query: 121 NDNYMEAFKKAEKLAEK-YLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKEK 179
Y A KKA LA+K +LVTFG+ KP+T +GYI+ + V+ F EK
Sbjct: 117 LQAYENAIKKAIDLAQKGFLVTFGVSIDKPNTEFGYIESPNGLDVK---------RFIEK 167
Query: 180 PDLETAKKYVENG-YYWNSGMFMFRTSVFMEEARKHAPETVRAFEEG-KSIEEIY----- 232
P L+ A ++ ++G +Y+NSGMF+F+ VF++E +KHAP ++ E +S+E Y
Sbjct: 168 PSLDKAIEFQKSGGFYFNSGMFVFQAGVFLDELKKHAPTILKGCERAFESLENAYFFEKK 227
Query: 233 ---------ELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYE--ALDKDENGNA 281
+ + ++S+D +M+++ K +V LN W+DLG+F+A++E A + EN +
Sbjct: 228 IARLSEKSMQDLEDMSIDIALMQQSHKIKMVELNAKWSDLGNFNALFEEAANEPKENVSL 287
Query: 282 VQVAGFKAKYININSRNNLILTERLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKR 341
Q F + S NNL+ + +++A +GVE+L ++DT DALL+A + + + +K +
Sbjct: 288 NQTPVFAKE-----SENNLVFSHKVSALLGVENLAVIDTKDALLIAHKDKAKDLKALVNE 342
Query: 342 LREENDERAIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVR 401
+ N E H YRPWGSY VL E YK+K + V P RLSLQ H+HRSEHWVV+
Sbjct: 343 VETNNQELLQTHTKVYRPWGSYEVLHESGCYKVKILEVKPNARLSLQKHFHRSEHWVVIS 402
Query: 402 GTAKVVVGDKEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDD 461
G A V + + F L+ EST+IP HRL N GK+ L +IE Q+GEY+GEDDIVR+ DD
Sbjct: 403 GMASVELDHQLFELQANESTYIPKNTLHRLANYGKIPLIIIEVQVGEYVGEDDIVRIDDD 462
Query: 462 FGRE 465
F R+
Sbjct: 463 FNRQ 466
>sp|Q07024|RFBA_VIBCH PUTATIVE MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE (GDP) (GDP-MANNOSE
PYROPHOSPHORYLASE) (GMP) >gi|280155|pir||S28468
mannose-1-phosphate guanyltransferase - Vibrio cholerae
>gi|48383|emb|CAA42134.1| (X59554) homologous to
phosphomannose isomerase of Pseudomonas aeruginosa and
RfbM of Salmonella typhimurium [Vibrio cholerae]
>gi|1586117|prf||2203285A phosphomannose isomerase
[Vibrio cholerae]
Length = 428
Score = 332 bits (842), Expect = 6e-90
Identities = 179/441 (40%), Positives = 263/441 (59%), Gaps = 29/441 (6%)
Query: 35 LFQKTVER--ALLFSKPKEIFIVTNKEYKFRVLDDLNELGLKVPEENILLEPVGKNTLPA 92
+ Q T+ER L ++P +++N++++F V + + G K I+LEP G+NT PA
Sbjct: 1 MLQATIERLQGLPIAEP---IVISNEDHRFIVAEQIRRYGKK---SRIILEPAGRNTAPA 54
Query: 93 IYWGLKVIDENYGDSVVAVLPSDHAIKVNDNYMEAFKKAEKLAEK-YLVTFGIKPTKPHT 151
I E D V+ VL +DH +K + A +A + AE L TFGI PT P T
Sbjct: 55 IALAAFTAIEQEDDPVLLVLAADHFVKNKSAFQAAISQAAQQAEAGKLATFGIVPTTPET 114
Query: 152 GYGYIKPGEKIKVEGKTIGYLVDEFKEKPDLETAKKYVENG-YYWNSGMFMFRTSVFMEE 210
GYGYI GE++ +G Y ++ F EKP L A++Y+ +G YYWNSG FMF+ SVF+ E
Sbjct: 115 GYGYIHRGEEV-TQGT---YEINSFVEKPQLNIAEQYLASGEYYWNSGCFMFKASVFLNE 170
Query: 211 ARKHAPETVRAFEEG-KSIEEIYELV----------PEISVDYGIMEKTDKAAVVPLNTY 259
++H+PE R E + + Y+ + P+ S+DY +ME T VV ++
Sbjct: 171 LKQHSPEIYRQCELAMQGLSHDYDFIRVGVEEFLKCPDDSIDYAVMEHTKLGVVVSMDAG 230
Query: 260 WNDLGSFDAVYEALDKDENGNAVQVAGFKAKYININSRNNLILTERLTATVGVEDLIIVD 319
W+D+GS+ A++E DKD +GN Q ++ S + +L A VG++D+++V+
Sbjct: 231 WSDVGSWSALWEVSDKDADGNVCQGDAI----LSGTSNCYIYAPNKLVAAVGLKDIVVVE 286
Query: 320 TGDALLVAKRGETQKVKEVYKRLREENDERAIVHRTAYRPWGSYTVLEEGERYKIKRITV 379
T DA+LVA + + Q+VK++ + L+ EN HR YRPWG +++GERYK+ RITV
Sbjct: 287 TKDAVLVADKNQVQEVKKIVEHLKAENRAEYREHRERYRPWGKSDAIDKGERYKVNRITV 346
Query: 380 LPGKRLSLQIHYHRSEHWVVVRGTAKVVVGDKEFILRPGESTFIPAGVPHRLENPGKVVL 439
PGK+ SLQ+HYHR+EHWVVV GTAKV ++ +S +IP G H +ENPGK+ L
Sbjct: 347 EPGKKQSLQMHYHRAEHWVVVSGTAKVTCEGNVKVITENQSLYIPIGTNHMIENPGKIPL 406
Query: 440 EVIETQIGEYLGEDDIVRLQD 460
E+IE Q G YL EDD+VR +D
Sbjct: 407 ELIEIQSGSYLNEDDVVRFED 427
>gb|AAC27538.1| (AF125322) ManC [Escherichia coli]
Length = 474
Score = 331 bits (839), Expect = 1e-89
Identities = 189/480 (39%), Positives = 286/480 (59%), Gaps = 36/480 (7%)
Query: 4 LILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVER--ALLFSKPKEIFIVTNKEYK 61
+IL+GG GTRLWPLSRE PKQF+K+ S+ Q T+ R +L S P ++ N+ ++
Sbjct: 8 VILSGGNGTRLWPLSREEYPKQFLKLTDSISMLQSTISRLDSLNTSSP---VVICNELHR 64
Query: 62 FRVLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENYGDS--VVAVLPSDHAIK 119
F V + L L + NI+LEP G+NT PAI ++ + + ++ VLP+DH++K
Sbjct: 65 FIVAEQLRHLNKL--DNNIILEPSGRNTAPAICIAALILKMKHPNENPLMLVLPADHSVK 122
Query: 120 VNDNYMEAFKKAEKLAEK-YLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDE--- 175
+ K A AE LV+FGIKPT P TGYGYI+ G KV + Y V E
Sbjct: 123 KVKTFCNTIKSAIPFAEAGNLVSFGIKPTHPETGYGYIQKG---KVLSDSDIYEVSEVRT 179
Query: 176 FKEKPDLETAKKYVENG-YYWNSGMFMFRTSVFMEEARKHAPETVRAFEEG-KSI----- 228
F EKP+L+TA+ ++E YYWNSGM++F +++E + P+ V+ +E K+I
Sbjct: 180 FVEKPNLKTAESFIEKDEYYWNSGMYLFSVERYLQELSLYRPDIVKVCQETVKNIHYDMD 239
Query: 229 -----EEIYELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQ 283
++I+ P+ S+DY +MEKT A V ++ WND+G++ +++E KD +GN +
Sbjct: 240 FIRLDDKIFRNCPQESIDYAVMEKTKDAVVATMDIGWNDVGAWSSLWELGKKDSSGNVIT 299
Query: 284 VAGFKAKYININSRNNLILTER-LTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRL 342
+ + N+ I TE L AT+G++DL+I+ T D+LLV++R Q VK + + L
Sbjct: 300 -----GDIVCHETENSYIYTESGLVATIGIQDLVIIHTKDSLLVSRRDSVQNVKNIVQHL 354
Query: 343 REENDERAIVHRTAYRPWGSYTVLEEGERY--KIKRITVLPGKRLSLQIHYHRSEHWVVV 400
+ HR ++ WG ++ E+Y ++KRITV P ++LSLQ+H+HR+EHWVVV
Sbjct: 355 DLSGRKEHKEHREVFKSWGRCDSIDSSEKYHYQVKRITVNPSEKLSLQLHHHRAEHWVVV 414
Query: 401 RGTAKVVVGDKEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQD 460
G AK+ V ++ IL+ ES +IPAG+ H LEN G + L +IE G YL +DDI+R +D
Sbjct: 415 MGIAKLTVAEEIKILKENESVYIPAGIKHSLENIGTIPLVLIEVWTGSYLADDDILRFED 474
>emb|CAA72316.1| (Y11554) mannose-6-phosphate isomerase [Acetobacter xylinus]
Length = 492
Score = 330 bits (836), Expect = 3e-89
Identities = 184/479 (38%), Positives = 277/479 (57%), Gaps = 27/479 (5%)
Query: 4 LILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERAL--LFSKPKEIFIVTNKEYK 61
+IL+GG GTRLWP+SR + PKQF + S R++ +T++RA F+ P +V N ++
Sbjct: 24 VILSGGTGTRLWPVSRASHPKQFWALASSRTMIGETLQRATGTAFAPP---IVVCNNAHR 80
Query: 62 FRVLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENYGDSVVAVLPSDHAIKVN 121
F V + L E G + + I+LEP +NT AI + ++ ++++ ++ +D +
Sbjct: 81 FLVAEQLRENGCE--DGRIILEPAVRNTAAAIAAAALLAAQDDPETLLWIMAADAVFRYP 138
Query: 122 DNYMEAFKKAEKLA-EKYLVTFGIKPTKPHTGYGYIKPGEKIKV-EGKTIGYLVDEFKEK 179
+ +KA +A E Y+VTFG+KP P TGYGYI+ G + + Y V F EK
Sbjct: 139 ERLPAVLEKAMTVAREGYIVTFGMKPDVPETGYGYIRLGAPLHSGDADDNVYRVARFIEK 198
Query: 180 PD-LETAKKYVENGYYWNSGMFMFRTSVFMEEARKHAPETVRAFEEGKSIEEI------- 231
PD L + E GY WNSGMF+ SV + E ++H P+ + E
Sbjct: 199 PDRLRATEMLNEGGYLWNSGMFLAPASVILAELKRHEPDVLENVRHALLHSESDLTFRRL 258
Query: 232 ----YELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAGF 287
+ P +S+DY +ME+TD+A V+P + W+D+G+++A++E DKD GN V
Sbjct: 259 ETASFMRCPNVSIDYAVMERTDRAVVIPADLGWSDVGNWNALWELGDKDAAGNVVV---- 314
Query: 288 KAKYININSRNNLILTE-RLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLREEN 346
+ S N + +E LTA G+ D+++V T DA+L R Q V + +L+
Sbjct: 315 -GDVVLEQSHNCYVRSEGMLTAVAGLTDIVLVVTSDAVLAIHRDYAQDVSALVSQLKMAR 373
Query: 347 DERAIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAKV 406
A +H YRPWG Y L +GER+++KRI V PG++LSLQ H+HR+EHWVVV GTA V
Sbjct: 374 RTEAEIHNRCYRPWGFYEGLIQGERFQVKRIVVYPGQKLSLQKHFHRAEHWVVVSGTAIV 433
Query: 407 VVGDKEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFGRE 465
+++ +L+ ES ++P G HRLENPG++ L +IE Q G YLGEDDIVR +D +GR+
Sbjct: 434 TRNEEKLMLQENESVYLPLGCMHRLENPGRIPLTLIEVQSGPYLGEDDIVRFEDTYGRQ 492
>gb|AAC46167.1| (AF017434) pmi-like gene product [Methylobacterium extorquens]
Length = 469
Score = 303 bits (767), Expect = 3e-81
Identities = 182/480 (37%), Positives = 270/480 (55%), Gaps = 32/480 (6%)
Query: 1 MKTLILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERAL--LFSKPKEIFIVTNK 58
++ +IL GG GTRLWP SR ++PKQF+ + S FQ+T+ R LF++P +V N+
Sbjct: 5 IQPVILCGGSGTRLWPTSRTSLPKQFVPLLGPHSTFQQTLLRLQGPLFARP---IVVANR 61
Query: 59 EYKFRVLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENYGDSVVAVLPSDHAI 118
+++ V + V +LLEP +++ PAI ++ ++VV VLPSDH +
Sbjct: 62 DHRCLVEKQAAAIDAGV---TLLLEPERRDSGPAILAACTLVAREDPEAVVLVLPSDHIV 118
Query: 119 KVNDNYMEAFKKAEKLAEK-YLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFK 177
+ A A A LVTFGI+ T YG+I+PG +++ + V F
Sbjct: 119 TEPRAFRRAVASALPAARAGRLVTFGIEADHASTEYGWIRPGTRVEARC----HAVHTFA 174
Query: 178 EKPDLETAKKYVENGYYWNSGMFMFRTSVFMEEARKHAPETVRAF--------EEGKSIE 229
EKPD A Y+ + + WNSG F+ R E P+T A +EG ++
Sbjct: 175 EKPDAARAATYLSDRWLWNSGNFLMRADTLCAEYAAFDPDTAAAAALAVEAAADEGGALA 234
Query: 230 ---EIYELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAG 286
E + + S+D+ +MEKT +AAV + W+D+G+++A++ ++D+ GN + A
Sbjct: 235 LDAEGFAGTHKTSLDFAVMEKTSRAAVARMRCGWSDVGNWNALWAISERDDLGNVSRGAA 294
Query: 287 --FKAKYININSRNNLILTERLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLRE 344
F + ++S +T+ VGV DL++V DA+LVA R V+++ + LR
Sbjct: 295 ELFDTEGCFVSSDG------MVTSLVGVRDLVVVAEKDAILVADRSRCGDVRKMVEILRS 348
Query: 345 ENDERAIVHRTAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTA 404
+ +A H +++RPWGSY VLE + +++KRITV PG RLSLQ H HR+EHWVVVRG A
Sbjct: 349 KGRPQAEWHASSHRPWGSYRVLEASDGFQVKRITVAPGGRLSLQKHRHRAEHWVVVRGCA 408
Query: 405 KVVVGDKEFILRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFGR 464
+V V D R E FIP G HRLENPG +E+IE Q+G YLGEDDIVRL+D + R
Sbjct: 409 RVTVDDTVADYRESEHIFIPLGAIHRLENPGNDDVELIEVQLGSYLGEDDIVRLEDAYHR 468
>sp|P37741|RFM7_ECOLI MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE (GDP) (GDP-MANNOSE
PYROPHOSPHORYLASE) (GMP) >gi|421038|pir||C40630
GDP-mannose pyrophosphorylase RfbM - Escherichia coli
Length = 464
Score = 269 bits (680), Expect = 5e-71
Identities = 165/452 (36%), Positives = 254/452 (55%), Gaps = 36/452 (7%)
Query: 4 LILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVER--ALLFSKPKEIFIVTNKEYK 61
+IL+GG GTRLWPLSRE PKQF+K+ S+ Q T+ R +L S P ++ N+ ++
Sbjct: 8 VILSGGNGTRLWPLSREEYPKQFLKLTDSISMLQSTISRLDSLNTSSP---VVICNELHR 64
Query: 62 FRVLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENYGDS--VVAVLPSDHAIK 119
F V + L L + NI+LEP G+NT PAI ++ + + ++ VLP+DH++K
Sbjct: 65 FIVAEQLRHLNKL--DNNIILEPSGRNTAPAICIAALILKMKHPNENPLMLVLPADHSVK 122
Query: 120 VNDNYMEAFKKAEKLAEK-YLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDE--- 175
+ K A AE LV+FGIKPT P TGYGYI+ G KV + Y V E
Sbjct: 123 KVKTFCNTIKSAIPFAEAGNLVSFGIKPTHPETGYGYIQKG---KVLSDSDIYEVSEVRT 179
Query: 176 FKEKPDLETAKKYVENG-YYWNSGMFMFRTSVFMEEARKHAPETVRAFEEG-KSI----- 228
F EKP+L+TA+ ++E YYWNSGM++F +++E + P+ V+ +E K+I
Sbjct: 180 FVEKPNLKTAESFIEKDEYYWNSGMYLFSVERYLQELSLYRPDIVKVCQETVKNIHYDMD 239
Query: 229 -----EEIYELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQ 283
++I+ P+ S+DY +MEKT A V ++ WND+G++ +++E KD +GN +
Sbjct: 240 FIRLDDKIFRNCPQESIDYAVMEKTKDAVVATMDIGWNDVGAWSSLWELGKKDSSGNVIT 299
Query: 284 VAGFKAKYININSRNNLILTER-LTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRL 342
+ + N+ I TE L AT+G++DL+I+ T D+LLV++R Q VK + + L
Sbjct: 300 -----GDIVCHETENSYIYTESGLVATIGIQDLVIIHTKDSLLVSRRDSVQNVKNIVQHL 354
Query: 343 REENDERAIVHRTAYRPWGSYTVLEEGER--YKIKRITVLPGKRLSLQIHYHRSEHWVVV 400
+ HR ++ WG ++ E+ Y++KRITV P + VVV
Sbjct: 355 DLSGRKEHKEHREVFKSWGRCDSIDSSEKYHYQVKRITVNPSENYRCNYIITVRNIGVVV 414
Query: 401 RGTAKVVVGDKEFILRPGESTFIPAGVPHRLE 432
G AK+ V ++ IL+ ES +IPAG+ H L+
Sbjct: 415 MGIAKLTVAEEIKILKENESVYIPAGIKHSLK 446
>pir||H72303 mannose-1-phosphate guanylyltransferase - Thermotoga maritima
(strain MSB8) >gi|4981574|gb|AAD36110.1|AE001764_13
(AE001764) mannose-1-phosphate guanylyltransferase
[Thermotoga maritima]
Length = 336
Score = 255 bits (644), Expect = 9e-67
Identities = 149/353 (42%), Positives = 212/353 (59%), Gaps = 33/353 (9%)
Query: 1 MKTLILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERALLFSKPKEIFIVTNKEY 60
MK LILAGG G R WPLS PKQF+K+F ++SL + T ER L PK++ +VT+K+Y
Sbjct: 2 MKALILAGGSGERFWPLSTPETPKQFLKLFGNKSLMRWTFERVLEEMDPKDVIVVTHKDY 61
Query: 61 KFRVLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENYGDSVVAVLPSDHAIKV 120
R +L EL P+ENI+ EP+ KNT PA + G K+ D+ D V VLP+DH I
Sbjct: 62 VERTKKELPEL----PDENIIAEPMKKNTAPACFIGTKLADD---DEPVLVLPADHRIPD 114
Query: 121 NDNYMEAFKKAEKLAEKY--LVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKE 178
+ + KKA EKY L TFGI PT+P TGYGYI+ GE+++ EG + V +F+E
Sbjct: 115 TKKFWKTVKKALDALEKYDGLFTFGIVPTRPETGYGYIEIGEELE-EGV---HKVAQFRE 170
Query: 179 KPDLETAKKYVENG-YYWNSGMFMFRTSVFMEEARKHAPETV--------RAFEEGKSIE 229
KPDLETAKK+VE+G + WNSGMF+++ F+EE + P R FEE ++
Sbjct: 171 KPDLETAKKFVESGRFLWNSGMFLWKAREFIEEVKVCEPSIYENLKDVDPRNFEE---LK 227
Query: 230 EIYELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAGFKA 289
+ YE VP ISVDY +MEK+ K VV + W+D+G++ +V E E + V +
Sbjct: 228 KAYEKVPSISVDYAVMEKSKKVRVVKADFEWSDVGNWSSVREIEGYTEESDEVILVDSDR 287
Query: 290 KYININSRNNLILTERLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRL 342
++ +++ A VG+ D+I++DT + +L+ K QKV+EV K+L
Sbjct: 288 VFVKTHNKP--------IAVVGLSDVIVIDTPNGILICKEEYAQKVREVVKKL 332
>dbj|BAA94400.1| (AB041266) GDP-mannose pyrophosphorylase homolog [Actinobacillus
actinomycetemcomitans]
Length = 341
Score = 254 bits (643), Expect = 1e-66
Identities = 157/359 (43%), Positives = 219/359 (60%), Gaps = 40/359 (11%)
Query: 1 MKTLILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERALLFSKPKEIFIVTNKEY 60
M LIL GG GTRLWPLSR +PKQFIK+F+ SLFQ T R FS+ K I +V + ++
Sbjct: 1 MINLILCGGSGTRLWPLSRVKVPKQFIKLFNHHSLFQLTQSRNAQFSE-KTIAVVNDTQF 59
Query: 61 --KFRVLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENYGDSVVAVLPSDHAI 118
+ D++N++ +LEPVG+NT PAI L Y D +V V SD I
Sbjct: 60 LLAYEQSDNVNQM-------KFILEPVGRNTAPAI--ALSCFGLEYND-IVLVTSSDQLI 109
Query: 119 KVNDNYMEAFKKAEKLAEK-YLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFK 177
K DNY+ KAEKLAEK +LVTFG+KP P TG+GYI E + E V F+
Sbjct: 110 KNQDNYLNMVCKAEKLAEKGFLVTFGLKPKYPETGFGYI---ETLDEEN------VLTFR 160
Query: 178 EKPDLETAKKYVENG-YYWNSGMFMFRTSVFMEEARKHAPE----TVRAFEEGKSIEEIY 232
EKPD +TAKKYVE+G Y+WN G+F F+ VF+EE K++P+ A+EE + I
Sbjct: 161 EKPDFDTAKKYVESGRYFWNCGIFCFKAGVFLEELLKYSPDIYYKAKEAYEERVINDNIE 220
Query: 233 EL-------VPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVA 285
+ +P S+DY +MEK+DK V+ + W+D+GSFD++ + K+++ N Q+
Sbjct: 221 SISLGNMLEIPSDSIDYAVMEKSDKIKVICGDLGWSDIGSFDSLEKEFAKNQDSNN-QI- 278
Query: 286 GFKAKYININSRNNLILTERLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLRE 344
+I+I+S NN I +++ T+ V+DLIIVDT D LLV K+G +QKVK+V + L+E
Sbjct: 279 ---EHHISISSSNNFIWSKKKIVTIDVDDLIIVDTDDVLLVVKKGSSQKVKKVVEYLKE 334
>pir||S75700 GDP-mannose pyrophosphorylase - Synechocystis sp. (strain PCC 6803)
>gi|1653346|dbj|BAA18261.1| (D90912) GDP-mannose
pyrophosphorylase [Synechocystis sp.]
Length = 367
Score = 213 bits (538), Expect = 2e-54
Identities = 133/352 (37%), Positives = 203/352 (56%), Gaps = 23/352 (6%)
Query: 4 LILAGGKGTRLWPLSREAMPKQFIKVF-SDRSLFQKTVERALLFSKPKE-IFIVTNKEYK 61
+ILAGGKG R WPLSR PKQF+ + S SL Q T +R L + E ++++T
Sbjct: 22 VILAGGKGERFWPLSRRQRPKQFLSLDGSGVSLLQATAQRLLSLAGDWENLWVITAAPIA 81
Query: 62 FRVLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENYGD-SVVAVLPSDHAIKV 120
V + L L P+EN L+EP GK+T PA+ W I + YGD +++ P+DH IK
Sbjct: 82 EGVFEQLPSL----PKENCLVEPEGKDTAPAVAWASLEIAQQYGDDAIIGFFPADHWIKD 137
Query: 121 NDNYMEAFKKAEKLAEKY--LVTFGIKPTKPHTGYGYIKPGE-KIKVEGKTIGYLVDEFK 177
Y + K A A++ +VT GIKP P TGYGYI+ G + +++G + Y V F
Sbjct: 138 QCAYEQTLKAAIAYAQEQDAIVTLGIKPHGPATGYGYIEQGTLEREIDGLPV-YQVTRFT 196
Query: 178 EKPDLETAKKYVENGYY-WNSGMFMFRTSVFMEEARKHAPETVRAFEEGKSIEEIYELVP 236
EKPD TA+ +V++G + WNSGMF+FR V + E +HAPE + + Y +
Sbjct: 197 EKPDRATAQTFVDSGKFSWNSGMFIFRAGVVLRELDRHAPELLATLRAKGAAG--YPALE 254
Query: 237 EISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAGFKAKYININS 296
+ S+DY +MEKT AAV+P N W+DLG ++A+ E L + N A ++N++S
Sbjct: 255 KKSIDYVLMEKTQLAAVLPANFGWDDLGDWNAL-ERLFPETEANV-----DLANHVNLHS 308
Query: 297 RNNLILT---ERLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLREE 345
R ++ ++ AT+G++D++IV G+ LV + TQ +K++ K+L+ +
Sbjct: 309 RGCIVYASDENQIIATIGLKDVVIVREGNVTLVVPKDHTQDIKDLLKQLQSQ 360
>pir||B75596 mannose-1-phosphate guanylyltransferase - Deinococcus radiodurans
(strain R1) >gi|6460570|gb|AAF12276.1|AE001862_102
(AE001862) mannose-1-phosphate guanylyltransferase
[Deinococcus radiodurans]
Length = 372
Score = 203 bits (511), Expect = 4e-51
Identities = 122/358 (34%), Positives = 204/358 (56%), Gaps = 29/358 (8%)
Query: 4 LILAGGKGTRLWPLSREAMPKQFIKVF-SDRSLFQKTVER-ALLFSKPKEIFIVTNKEYK 61
+ILAGG G R WPLSR PKQF+ + S RSL Q T +R A L + +VT +Y+
Sbjct: 17 VILAGGSGERFWPLSRRHRPKQFLTLDESGRSLLQATSDRLARLGGGQDRVVVVTGNDYR 76
Query: 62 FRVLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENYGDSVVAVLPSDHAIKVN 121
+VL+ L E+ P EN+L+EP ++T AI + I ++ +V+ V P+DH +
Sbjct: 77 SQVLEQLPEM----PIENLLVEPAARDTAAAILYAALWIAQDDPQAVMGVFPADHRVTDV 132
Query: 122 DNYMEAFKKAEKLAEKY--LVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKEK 179
+ + ++A ++A++ LVT GI PT P TGYGYI+ GE ++ G+ + V F EK
Sbjct: 133 EAFERVIQRAIEVAQESERLVTVGIAPTFPSTGYGYIQQGEVLQ-PGELPAFSVTRFTEK 191
Query: 180 PDLETAKKYVENGYY-WNSGMFMFRTSVFMEEARKHAPETVRAFEEGKS----------I 228
PD TA+ +++ G Y WNSGMF++R + +H P+ + + S +
Sbjct: 192 PDAVTAQAFLDTGRYTWNSGMFIWRVQSILAAFEQHQPQLYKQLHQVMSAGTASARRVQL 251
Query: 229 EEIYELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAGFK 288
+ + + +IS+DY I+EK+D+ AV+P W+DLG ++A+ E L K E N
Sbjct: 252 QTTFPQLEKISIDYAILEKSDRVAVIPAEFGWDDLGDWNAL-ERLLKGEGDNVA-----V 305
Query: 289 AKYININSRNNLILT---ERLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRLR 343
+++ +++ ++ T + L AT+G++D+++V D LV ++ TQ +K+V ++L+
Sbjct: 306 GRHVGLDTGGAILYTTNGDDLIATIGLDDVVVVRAEDVTLVVRKDRTQDIKKVVQQLK 363
>gb|AAA02893.1| (M77127) phosphomanose isomerase [Escherichia coli]
Length = 152
Score = 166 bits (417), Expect = 4e-40
Identities = 76/151 (50%), Positives = 105/151 (69%)
Query: 314 DLIIVDTGDALLVAKRGETQKVKEVYKRLREENDERAIVHRTAYRPWGSYTVLEEGERYK 373
DL++V T DA+L+A R Q VK+V ++++ + VHR YRPWG Y ++ G+RY+
Sbjct: 1 DLVVVQTKDAVLIADRNAVQDVKKVVEQIKADGRHEHRVHREVYRPWGKYDSIDAGDRYQ 60
Query: 374 IKRITVLPGKRLSLQIHYHRSEHWVVVRGTAKVVVGDKEFILRPGESTFIPAGVPHRLEN 433
+KRITV PG+ LS+Q+H+HR+EHWVVV GTAKV + +L ES +IP G H LEN
Sbjct: 61 VKRITVKPGEGLSVQMHHHRAEHWVVVAGTAKVTIDGDIKLLGENESIYIPLGATHCLEN 120
Query: 434 PGKVVLEVIETQIGEYLGEDDIVRLQDDFGR 464
PGK+ L++IE + G YL EDD+VR D +GR
Sbjct: 121 PGKIPLDLIEVRSGSYLEEDDVVRFADRYGR 151
>gb|AAC80269.1| (AF031957) GDP-mannose pyrophosphorylase [Shigella sonnei]
Length = 150
Score = 162 bits (406), Expect = 7e-39
Identities = 74/149 (49%), Positives = 103/149 (68%)
Query: 316 IIVDTGDALLVAKRGETQKVKEVYKRLREENDERAIVHRTAYRPWGSYTVLEEGERYKIK 375
++V T DA+L+A R Q VK+V ++++ + VHR YRPWG Y ++ G+RY++K
Sbjct: 1 VVVQTKDAVLIADRNAVQDVKKVVEQIKADGRHEHRVHREVYRPWGKYDSIDAGDRYQVK 60
Query: 376 RITVLPGKRLSLQIHYHRSEHWVVVRGTAKVVVGDKEFILRPGESTFIPAGVPHRLENPG 435
RITV PG+ LS+Q+H+HR+EHWVVV GTAKV + +L ES +IP G H LENPG
Sbjct: 61 RITVKPGEGLSVQMHHHRAEHWVVVAGTAKVTIDGDIKLLGENESIYIPLGAMHCLENPG 120
Query: 436 KVVLEVIETQIGEYLGEDDIVRLQDDFGR 464
K+ L++IE + G YL EDD+VR D +GR
Sbjct: 121 KIPLDLIEVRSGSYLEEDDVVRFADRYGR 149
>pir||S74405 mannose-6-phosphate isomerase (EC 5.3.1.8) rfbM - Synechocystis sp.
(strain PCC 6803) >gi|1001180|dbj|BAA10323.1| (D64001)
phosphomannose isomerase [Synechocystis sp.]
Length = 128
Score = 159 bits (397), Expect = 8e-38
Identities = 72/110 (65%), Positives = 86/110 (77%)
Query: 355 TAYRPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAKVVVGDKEFI 414
T RPWGS+T LEEG YKIKRI V PG RLSLQ+H+HRSEHW+VV GTA++V GDKE +
Sbjct: 18 TETRPWGSFTTLEEGNGYKIKRIEVNPGHRLSLQMHHHRSEHWIVVSGTARIVCGDKEEL 77
Query: 415 LRPGESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFGR 464
L P +ST++P HRLENPG + L +IE Q GEYLGEDDI+R QDD+ R
Sbjct: 78 LEPNQSTYVPQCTAHRLENPGVIKLVLIEVQNGEYLGEDDIIRFQDDYAR 127
>dbj|BAA08633.1| (D49826) unnamed protein product [Serratia marcescens]
Length = 244
Score = 154 bits (385), Expect = 2e-36
Identities = 90/229 (39%), Positives = 136/229 (59%), Gaps = 11/229 (4%)
Query: 4 LILAGGKGTRLWPLSREAMPKQFIKV-FSDRSLFQKTVER--ALLFSKPKEIFIVTNKEY 60
+++AGG G+RLWP+SRE+ PKQF+ + S SL Q+T++R L + ++ N+E+
Sbjct: 7 VVMAGGTGSRLWPMSRESFPKQFLSIDDSGVSLLQQTLQRLSGLTGIEVAAPLVICNEEH 66
Query: 61 KFRVLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENYGDSVVAVLPSDHAIKV 120
+F V + L +G NI+LEPV +NT PA+ + E S++ VL +DH I
Sbjct: 67 RFLVAEQLRGIGQLA--TNIILEPVARNTAPAVALAAHLAAEKDEGSMLLVLAADHLITK 124
Query: 121 NDNYMEAFKKAEKLAE-KYLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKEK 179
+N+ A + A A+ LVTFGI P P TGYGYIK G + + + VD F EK
Sbjct: 125 VENFHAAIQTAMSFADNNQLVTFGIIPEHPETGYGYIKRGSHLSND----CFKVDSFVEK 180
Query: 180 PDLETAKKYVENG-YYWNSGMFMFRTSVFMEEARKHAPETVRAFEEGKS 227
P LE A +Y+ +G Y WNSGMFMF+T+ F++E ++ +P+ ++ S
Sbjct: 181 PRLEKAIEYLASGDYSWNSGMFMFKTAKFLQELQQFSPDIFSTTQQSVS 229
>pir||S77561 mannose-6-phosphate isomerase (EC 5.3.1.8) manA - Synechocystis sp.
(strain PCC 6803) >gi|1652486|dbj|BAA17408.1| (D90905)
mannose-6-phosphate isomerase [Synechocystis sp.]
Length = 129
Score = 136 bits (340), Expect = 4e-31
Identities = 61/103 (59%), Positives = 77/103 (74%)
Query: 359 PWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAKVVVGDKEFILRPG 418
PWG T+LEEG RY+I RI V PG+ +S Q+HYHRSEHWVVV GTAKV+ +E +L
Sbjct: 23 PWGMVTMLEEGPRYRINRIVVKPGQHMSTQMHYHRSEHWVVVSGTAKVICNGEEKLLNQK 82
Query: 419 ESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDD 461
EST++P PHR+ENPG + L +IE Q GEYLG+DDIVR ++
Sbjct: 83 ESTYVPMNTPHRVENPGVIDLVMIEVQNGEYLGDDDIVRFPEE 125
>pir||S04426 hypothetical protein - Synechococcus sp >gi|1405429|emb|CAA35492.1|
(X17442) orf150 [Synechococcus PCC6301]
Length = 150
Score = 130 bits (323), Expect = 4e-29
Identities = 59/107 (55%), Positives = 79/107 (73%)
Query: 358 RPWGSYTVLEEGERYKIKRITVLPGKRLSLQIHYHRSEHWVVVRGTAKVVVGDKEFILRP 417
RPWG + +L +G Y++KR+ VLPG++LSLQ H R EHW+VV+G A+V +GD++F LR
Sbjct: 40 RPWGQFEILAQGSGYQVKRLEVLPGQQLSLQRHQQRQEHWLVVQGLARVQLGDRQFSLRV 99
Query: 418 GESTFIPAGVPHRLENPGKVVLEVIETQIGEYLGEDDIVRLQDDFGR 464
G+S I G HRL+NPG +L +IE Q+G YLGEDDI R DD+GR
Sbjct: 100 GQSLDIAIGEWHRLQNPGDELLALIEVQMGAYLGEDDIERRADDYGR 146
>emb|CAA67491.1| (X99019) AlgA protein [Azotobacter vinelandii]
Length = 186
Score = 127 bits (316), Expect = 3e-28
Identities = 77/184 (41%), Positives = 112/184 (60%), Gaps = 6/184 (3%)
Query: 1 MKTLILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERALLFSKPKEIFIVTNKEY 60
M +IL+GG G+RLWPLSR+ PKQF+ + S+R+LFQ+T++R L F + +V N+E+
Sbjct: 1 MIPVILSGGSGSRLWPLSRKQYPKQFLALTSERTLFQQTLQR-LNFEGMQSPIVVCNQEH 59
Query: 61 KFRVLDDLNELGLKVPEENILLEPVGKNTLPAI-YWGLKVIDENYGDSVVAVLPSDHAIK 119
+F V + L +GL + + +LLEP G+NT PAI +K++ E D ++ +LP+DH I
Sbjct: 60 RFIVKEQLEAIGLNI--QGLLLEPFGRNTAPAIALTAMKLLAEG-RDELLLILPADHVIA 116
Query: 120 VNDNYMEAFKKAEKLAEK-YLVTFGIKPTKPHTGYGYIKPGEKIKVEGKTIGYLVDEFKE 178
+ +A K A + AE LV FGI P TGYGYIK ++ V +F E
Sbjct: 117 DQQAFQQALKVAAQAAEMGELVLFGIPAHSPETGYGYIKCDLAVQGTLPEGSNRVLQFVE 176
Query: 179 KPDL 182
KPDL
Sbjct: 177 KPDL 180
>gb|AAG20296.1| (AE005104) mannose-1-phosphate guanylyltransferase; ManC
[Halobacterium sp. NRC-1]
Length = 227
Score = 125 bits (311), Expect = 1e-27
Identities = 81/235 (34%), Positives = 126/235 (53%), Gaps = 19/235 (8%)
Query: 112 LPSDHAIKVNDNYMEAFKKAEKLAEKY--LVTFGIKPTKPHTGYGYIKPGEKIKVEGKTI 169
LPSDH V D + E + A +A + LVT GI+P +P TGYGYI+PG+ +
Sbjct: 4 LPSDHV--VGDGFQETAETAVDVAARTDGLVTIGIEPDRPATGYGYIEPGDDHGDHSE-- 59
Query: 170 GYLVDEFKEKPDLETAKKYVENGYYWNSGMFMFRTSVFMEEARKHAPE-TVRAFEEGKSI 228
V F+EKPD ETA + V+ G WN+GMF + + F++ AR + V A
Sbjct: 60 ---VAVFREKPDAETASRLVDRGCLWNAGMFAWTPTAFLDAARSGPLDPLVDALATDADP 116
Query: 229 EEIYELVPEISVDYGIMEKTDKAAVVPLNTYWNDLGSFDAVYEALDKDENGNAVQVAGFK 288
+E V +SVDY ++E+ VVP W+DLG+++A+ LD + NAV
Sbjct: 117 ATAFERVDPVSVDYAVLERAADVRVVPAAFDWDDLGAWNALGRLLDGE---NAV-----L 168
Query: 289 AKYININSRNNLILT-ERLTATVGVEDLIIVDTGDALLVAKRGETQKVKEVYKRL 342
I++ N++ + ++ + VGV+DL++ D +LV R + Q+V++V L
Sbjct: 169 GDATTIDATGNVLASDDKHVSVVGVDDLVVAAYDDRVLVVPRADAQRVRDVVAAL 223
>emb|CAA10658.1| (AJ132366) mannose 6 phosphate isomerase [Helicobacter pylori]
Length = 117
Score = 77.6 bits (188), Expect = 3e-13
Identities = 46/119 (38%), Positives = 70/119 (58%), Gaps = 6/119 (5%)
Query: 1 MKTLILAGGKGTRLWPLSREAMPKQFIKVFSDRSLFQKTVERALLFSKPKEIFIVTNKEY 60
+K ++L+GG G RLWPLSR PKQF+K+F+ +SLF+ + +R S E IV N+++
Sbjct: 3 IKNILLSGGSGKRLWPLSRSLYPKQFLKLFNHKSLFELSFKRNA--SLVDETLIVCNEKH 60
Query: 61 KFRVLDDLNELGLKVPEENILLEPVGKNTLPAIYWGLKVIDENYGDSVVAVLPSDHAIK 119
F L+++ E +K LLE + KNT AI + + + ++ V PSDH IK
Sbjct: 61 YFLALEEI-ESEIKNKSVGFLLESLSKNTANAIALSALMSER---EDLLIVTPSDHLIK 115
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.317 0.138 0.397
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 179925790
Number of Sequences: 2977
Number of extensions: 8103392
Number of successful extensions: 24712
Number of sequences better than 1.0e-10: 65
Number of HSP's better than 0.0 without gapping: 57
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 24302
Number of HSP's gapped (non-prelim): 65
length of query: 465
length of database: 189,106,746
effective HSP length: 57
effective length of query: 408
effective length of database: 154,992,987
effective search space: 63237138696
effective search space used: 63237138696
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.6 bits)
S2: 167 (69.5 bits)