BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0832 (dapA) DE:dihydrodipicolinate synthase (dapA)
(294 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||H75033 dihydrodipicolinate synthase (dapa) PAB0832 - Pyroco... 585 e-166
pir||C71135 probable dihydrodipicoline synthase - Pyrococcus hor... 462 e-129
gb|AAK43171.1| Dihydrodipicolinate synthase (dapA-3) [Sulfolobus... 256 2e-67
pir||S56523 dihydrodipicolinate synthase homolog yjhH - Escheric... 190 2e-47
sp|P39359|YJHH_ECOLI HYPOTHETICAL 32.7 KDA PROTEIN IN FECI-FIMB ... 190 2e-47
sp|P75682|YAGE_ECOLI HYPOTHETICAL 33.3 KD PROTEIN IN PERR-ARGF I... 168 6e-41
gb|AAK42436.1| Dihydrodipicolinate synthase (dapA-1) [Sulfolobus... 155 7e-37
gi|11498515 dihydrodipicolinate synthase (dapA) [Archaeoglobus f... 145 8e-34
sp|Q57695|DAPA_METJA DIHYDRODIPICOLINATE SYNTHASE (DHDPS) >gi|21... 144 1e-33
sp|Q9X1K9|DAPA_THEMA DIHYDRODIPICOLINATE SYNTHASE (DHDPS) >gi|74... 143 3e-33
sp|O67216|DAPA_AQUAE DIHYDRODIPICOLINATE SYNTHASE (DHDPS) >gi|74... 130 2e-29
pir||D81393 probable lyase Cj0481 [imported] - Campylobacter jej... 127 1e-28
emb|CAC12282.1| (AL445066) dihydrodipicoline synthase related pr... 127 2e-28
dbj|BAB05461.1| (AP001513) dihydrodipicolinate synthase [Bacillu... 126 3e-28
sp|O26892|DAPA_METTH DIHYDRODIPICOLINATE SYNTHASE (DHDPS) >gi|74... 126 3e-28
gb|AAG18989.1| (AE004999) dihydrodipicolinate synthase; DapA [Ha... 125 6e-28
sp|Q07607|MOSA_RHIME MOSA PROTEIN >gi|1073154|pir||B53308 mosA p... 120 2e-26
sp|Q9ZM13|DAPA_HELPJ DIHYDRODIPICOLINATE SYNTHASE (DHDPS) >gi|74... 116 3e-25
sp|O25657|DAPA_HELPY DIHYDRODIPICOLINATE SYNTHASE (DHDPS) >gi|74... 115 5e-25
gb|AAK43294.1| 2-keto-3-deoxy gluconate aldolase (eda) [Sulfolob... 115 9e-25
emb|CAA11866.1| (AJ224174) 2-keto-3-deoxy gluconate aldolase [Su... 115 9e-25
pir||C83520 dihydrodipicolinate synthase PA1010 [imported] - Pse... 114 1e-24
pir||D81141 dihydrodipicolinate synthase NMB0929 [imported] - Ne... 113 2e-24
gb|AAF04320.1| (AF065159) dihydrodipicolinate synthase [Bradyrhi... 112 6e-24
dbj|BAB06118.1| (AP001515) dihydrodipicolinate synthase [Bacillu... 111 1e-23
gb|AAK43137.1| Dihydrodipicolinate synthase (dapA-2) [Sulfolobus... 111 1e-23
sp|Q04796|DAPA_BACSU DIHYDRODIPICOLINATE SYNTHASE (DHDPS) (VEGET... 110 2e-23
sp|P40109|DAPA_BRELA DIHYDRODIPICOLINATE SYNTHASE (DHDPS) >gi|42... 110 2e-23
pir||H81878 probable dihydrodipicolinate synthase (EC 4.2.1.52) ... 109 3e-23
sp|P19808|DAPA_CORGL DIHYDRODIPICOLINATE SYNTHASE (DHDPS) >gi|40... 109 5e-23
pir||F81352 dihydrodipicolinate synthase (EC 4.2.1.52) Cj0806 [i... 109 5e-23
emb|CAC11758.1| (AL445064) probable 2-keto-3-deoxy gluconate ald... 106 3e-22
sp|P43797|DAPA_HAEIN DIHYDRODIPICOLINATE SYNTHASE (DHDPS) >gi|10... 102 5e-21
sp|P05640|DAPA_ECOLI DIHYDRODIPICOLINATE SYNTHASE (DHDPS) >gi|74... 102 5e-21
gb|AAA23665.1| (M12844) dihydrodipicolinate synthetase (dapA) [E... 101 8e-21
pir||H82113 dihydrodipicolinate synthase VC2157 [imported] - Vib... 100 2e-20
sp|P06995|NPL_ECOLI N-ACETYLNEURAMINATE LYASE SUBUNIT (N-ACETYLN... 98 1e-19
pdb|1FDZ|A Chain A, N-Acetylneuraminate Lyase In Complex With Py... 96 4e-19
pir||H72700 N-acetylneuraminate lyase homolog APE1023 [imported]... 96 5e-19
sp|P57197|DAPA_BUCAI DIHYDRODIPICOLINATE SYNTHASE (DHDPS) >gi|10... 96 5e-19
sp|Q55513|DAPA_SYNY3 DIHYDRODIPICOLINATE SYNTHASE (DHDPS) >gi|74... 96 6e-19
emb|CAA27051.1| (X03345) N-acetylneuraminate lyase (EC 4.1.3.3) ... 95 8e-19
pdb|1NAL|1 Chain 1, Mol_id: 1; Molecule: N-Acetylneuraminate Lya... 95 8e-19
emb|CAA73375.1| (Y12876) N-acetylneuraminate lyase [Clostridium ... 95 1e-18
pir||B83122 conserved hypothetical protein PA4188 [imported] - P... 95 1e-18
gb|AAD28763.1|AF130859_2 (AF130859) sialic acid lyase [Clostridi... 94 1e-18
pir||T36926 dihydrodipicolinate synthase (EC 4.2.1.52) SCI7.30 [... 94 1e-18
gb|AAF00009.1|AF056977_1 (AF056977) hypothetical protein [Penici... 93 3e-18
sp|O69782|DAPA_RHIME DIHYDRODIPICOLINATE SYNTHASE (DHDPS) >gi|30... 92 7e-18
gb|AAB42182.1| (U35878) N-acetylneuraminate lyase [Trichomonas v... 89 5e-17
pir||D83488 probable dihydrodipicolinate synthetase PA1254 [impo... 89 5e-17
sp|P49423|DAPA_PROMA DIHYDRODIPICOLINATE SYNTHASE (DHDPS) >gi|10... 88 1e-16
pir||G83617 probable dihydrodipicolinate synthetase PA0223 [impo... 87 2e-16
sp|O05969|DAPA_RICPR DIHYDRODIPICOLINATE SYNTHASE (DHDPS) >gi|74... 87 3e-16
pir||T35844 dihydrodipicolinate synthase (EC 4.2.1.52) SC9A10.08... 86 4e-16
emb|CAA69950.1| (Y08695) putative acylneuraminate lyase [Clostri... 86 5e-16
pir||H70879 dihydrodipicolinate synthase (EC 4.2.1.52) Rv2753c [... 86 5e-16
pir||D82742 dihydroxydipicolinate synthase XF0963 [imported] - X... 86 5e-16
gb|AAG23543.1|AF244594_1 (AF244594) dihydropicolinate synthase [... 86 5e-16
pdb|1F6P|A Chain A, Crystal Structure Analysis Of N-Acetylneuram... 83 5e-15
sp|P44539|NPL_HAEIN PROBABLE N-ACETYLNEURAMINATE LYASE SUBUNIT (... 82 1e-14
pir||E82157 probable N-acetylneuraminate lyase VC1776 [imported]... 81 1e-14
sp|P42235|KDGD_BACSU PROBABLE 5-DEHYDRO-4-DEOXYGLUCARATE DEHYDRA... 80 3e-14
dbj|BAA77934.1| (D83536) Hypothetical protein F319 [Escherichia ... 78 2e-13
sp|P26259|DAPA_MAIZE DIHYDRODIPICOLINATE SYNTHASE PRECURSOR (DHDPS) 72 9e-12
prf||1718320A dihydrodipicolinate synthase [Zea mays] 72 9e-12
prf||2208495A dihydrodipicolinate synthase [Zea mays] 72 9e-12
pir||WZZMP dihydrodipicolinate synthase (EC 4.2.1.52) precursor ... 72 9e-12
sp|Q39535|DAPA_COILA DIHYDRODIPICOLINATE SYNTHASE PRECURSOR (DHD... 71 1e-11
pir||T36909 probable dihydropicolinate synthase - Streptomyces c... 71 1e-11
gb|AAF44718.1|L77616_1 (L77616) dihydrodipicolinate synthase [Or... 70 3e-11
sp|P24846|DAP1_WHEAT DIHYDRODIPICOLINATE SYNTHASE 1 PRECURSOR (D... 69 6e-11
pir||T47899 dihydrodipicolinate synthase precursor - Arabidopsis... 69 6e-11
sp|Q42948|DAPA_TOBAC DIHYDRODIPICOLINATE SYNTHASE PRECURSOR (DHD... 69 8e-11
>pir||H75033 dihydrodipicolinate synthase (dapa) PAB0832 - Pyrococcus abyssi
(strain Orsay) >gi|5458678|emb|CAB50165.1| (AJ248287)
dihydrodipicolinate synthase (dapA) [Pyrococcus abyssi]
Length = 294
Score = 585 bits (1493), Expect = e-166
Identities = 294/294 (100%), Positives = 294/294 (100%)
Query: 1 MEGVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAE 60
MEGVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAE
Sbjct: 1 MEGVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAE 60
Query: 61 KGREITSGMYLVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMVA 120
KGREITSGMYLVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMVA
Sbjct: 61 KGREITSGMYLVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMVA 120
Query: 121 ERVDIPIIVYAIPSCANPVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEERKDF 180
ERVDIPIIVYAIPSCANPVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEERKDF
Sbjct: 121 ERVDIPIIVYAIPSCANPVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEERKDF 180
Query: 181 RVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRVLGEISR 240
RVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRVLGEISR
Sbjct: 181 RVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRVLGEISR 240
Query: 241 IYNVASSFASAVKLAMIAKGFPIKPVLRPPHVIDGEEVFNEIKGILRSLENVKP 294
IYNVASSFASAVKLAMIAKGFPIKPVLRPPHVIDGEEVFNEIKGILRSLENVKP
Sbjct: 241 IYNVASSFASAVKLAMIAKGFPIKPVLRPPHVIDGEEVFNEIKGILRSLENVKP 294
>pir||C71135 probable dihydrodipicoline synthase - Pyrococcus horikoshii
>gi|3257258|dbj|BAA29941.1| (AP000003) 287aa long
hypothetical dihydrodipicoline synthase [Pyrococcus
horikoshii]
Length = 287
Score = 462 bits (1177), Expect = e-129
Identities = 214/286 (74%), Positives = 265/286 (91%)
Query: 1 MEGVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAE 60
MEGVIVPL+TPF+ED+SIDFEALEW I+FLEEKGVHGIF+NSTTGEFTSL+ +ERK+LAE
Sbjct: 1 MEGVIVPLITPFKEDHSIDFEALEWLIKFLEEKGVHGIFINSTTGEFTSLSLEERKILAE 60
Query: 61 KGREITSGMYLVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMVA 120
KGRE+TS YLVGTGSTST EVIEL++HA++IGADG+VIV+PYYC+LK++ I KHFSMVA
Sbjct: 61 KGREVTSRTYLVGTGSTSTFEVIELTKHAKEIGADGVVIVSPYYCRLKEDAIFKHFSMVA 120
Query: 121 ERVDIPIIVYAIPSCANPVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEERKDF 180
E+VDIPII+YAIPSCANP+ ++++RK++LEYSN+IGVKASVDSLTYL LIE+KEERKDF
Sbjct: 121 EKVDIPIILYAIPSCANPISLEVVRKLALEYSNVIGVKASVDSLTYLSGLIEIKEERKDF 180
Query: 181 RVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRVLGEISR 240
+VFTGLDQYFL L+LGGDGGIMACANF PEIHL++WN+FK+ N E+A+ +R L +I++
Sbjct: 181 KVFTGLDQYFLPNLILGGDGGIMACANFVPEIHLEVWNAFKKGNLEKAMNSARKLVKITK 240
Query: 241 IYNVASSFASAVKLAMIAKGFPIKPVLRPPHVIDGEEVFNEIKGIL 286
IY++ASSFASAVKLAM+A+GFPIKP+LRPP+++DGEEVF +IK I+
Sbjct: 241 IYSIASSFASAVKLAMVARGFPIKPILRPPYMMDGEEVFKKIKEIV 286
>gb|AAK43171.1| Dihydrodipicolinate synthase (dapA-3) [Sulfolobus solfataricus]
Length = 302
Score = 256 bits (648), Expect = 2e-67
Identities = 127/296 (42%), Positives = 201/296 (67%), Gaps = 7/296 (2%)
Query: 1 MEGVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKM--- 57
+EGV+VPL+TPF EDYSID E L+W + +L E GV+GIFVNS+ GEF SL DE K+
Sbjct: 3 LEGVVVPLITPFLEDYSIDKEGLKWLVSYLSENGVNGIFVNSSVGEFASLTLDEMKLVTK 62
Query: 58 LAEKGREITSGMYLVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFS 117
+A R+ S + G + T E I+L++ +D+G D IV++APY+ K++++E+L HFS
Sbjct: 63 IALDSRKSYSTLIFAGASTNFTEETIKLAKDFKDMGVDAIVVMAPYFFKVREKELLDHFS 122
Query: 118 MVAERVDIPIIVYAIPSCAN-PVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELI-EVKE 175
M+AE+VD+PII+Y IP +P+ + + + ++SNIIG K ++DSL + ++LI E++E
Sbjct: 123 MIAEKVDLPIIIYNIPLFTGIDIPISVYKMLVSQHSNIIGTKVTLDSLIFFKKLISEIRE 182
Query: 176 ERKDFRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRVL 235
RKDF + TG D+Y L L +GG+GG+M AN P++HL+++ S+K N +A K R +
Sbjct: 183 IRKDFSILTGFDEYLLPLLYMGGNGGVMGLANAIPKLHLKVYESWKNGNLSDANKYWRNV 242
Query: 236 GEISRIYNVASSFASAVKLAMIAKGFPIKPVLRPPHVIDGEEVFNEIKGILRSLEN 291
++ IY+ +S+ +++KL + PIK V+RPP I EE ++I+G+++ L +
Sbjct: 243 LNLTDIYDYCNSYTASIKLLLKVLNMPIKNVVRPPLSICEEE--SKIRGMIKDLSS 296
>pir||S56523 dihydrodipicolinate synthase homolog yjhH - Escherichia coli
>gi|537139|gb|AAA97194.1| (U14003) ORF_f319 [Escherichia
coli] >gi|1790751|gb|AAC77254.1| (AE000500) putative
lyase/synthase [Escherichia coli K12]
Length = 319
Score = 190 bits (477), Expect = 2e-47
Identities = 102/288 (35%), Positives = 169/288 (58%), Gaps = 4/288 (1%)
Query: 3 GVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEKG 62
G+I P+ + F D ++D +A+ FL KGV G+F T GEF+ +NT +R LAE+
Sbjct: 24 GIIPPVSSTFHRDGTLDKKAMREVADFLINKGVDGLFYLGTGGEFSQMNTAQRMALAEEA 83
Query: 63 REITSGMY--LVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMVA 120
I G L+G GS ST E ++L++HA+ GADGIV + PYY K+ + ++ +A
Sbjct: 84 VTIVDGRVPVLIGVGSPSTDEAVKLAQHAQAYGADGIVAINPYYWKVAPRNLDDYYQQIA 143
Query: 121 ERVDIPIIVYAIPSCANP-VPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIE-VKEERK 178
V +P+I+Y P + + + +++L+ NI+G+K ++DS+ +L+ +I VK R
Sbjct: 144 RSVTLPVILYNFPDLTGQDLTPETVTRLALQNENIVGIKDTIDSVGHLRTMINTVKSVRP 203
Query: 179 DFRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRVLGEI 238
F VF G D + L+T+LLGGDG I A ANFAPE+ + I+ +++ + A L++ L ++
Sbjct: 204 SFSVFCGYDDHLLNTMLLGGDGAITASANFAPELSVGIYRAWREGDLATAATLNKKLLQL 263
Query: 239 SRIYNVASSFASAVKLAMIAKGFPIKPVLRPPHVIDGEEVFNEIKGIL 286
IY + + F S +K +M G P++ PP + EE +++ +L
Sbjct: 264 PAIYALETPFVSLIKYSMQCVGLPVETYCLPPILEASEEAKDKVHVLL 311
>sp|P39359|YJHH_ECOLI HYPOTHETICAL 32.7 KDA PROTEIN IN FECI-FIMB INTERGENIC REGION
Length = 301
Score = 190 bits (477), Expect = 2e-47
Identities = 102/288 (35%), Positives = 169/288 (58%), Gaps = 4/288 (1%)
Query: 3 GVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEKG 62
G+I P+ + F D ++D +A+ FL KGV G+F T GEF+ +NT +R LAE+
Sbjct: 6 GIIPPVSSTFHRDGTLDKKAMREVADFLINKGVDGLFYLGTGGEFSQMNTAQRMALAEEA 65
Query: 63 REITSGMY--LVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMVA 120
I G L+G GS ST E ++L++HA+ GADGIV + PYY K+ + ++ +A
Sbjct: 66 VTIVDGRVPVLIGVGSPSTDEAVKLAQHAQAYGADGIVAINPYYWKVAPRNLDDYYQQIA 125
Query: 121 ERVDIPIIVYAIPSCANP-VPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIE-VKEERK 178
V +P+I+Y P + + + +++L+ NI+G+K ++DS+ +L+ +I VK R
Sbjct: 126 RSVTLPVILYNFPDLTGQDLTPETVTRLALQNENIVGIKDTIDSVGHLRTMINTVKSVRP 185
Query: 179 DFRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRVLGEI 238
F VF G D + L+T+LLGGDG I A ANFAPE+ + I+ +++ + A L++ L ++
Sbjct: 186 SFSVFCGYDDHLLNTMLLGGDGAITASANFAPELSVGIYRAWREGDLATAATLNKKLLQL 245
Query: 239 SRIYNVASSFASAVKLAMIAKGFPIKPVLRPPHVIDGEEVFNEIKGIL 286
IY + + F S +K +M G P++ PP + EE +++ +L
Sbjct: 246 PAIYALETPFVSLIKYSMQCVGLPVETYCLPPILEASEEAKDKVHVLL 293
>sp|P75682|YAGE_ECOLI HYPOTHETICAL 33.3 KD PROTEIN IN PERR-ARGF INTERGENIC REGION
>gi|7436667|pir||D64752 dihydrodipicolinate synthase
homolog yagE - Escherichia coli
>gi|1786463|gb|AAC73371.1| (AE000134) putative
lyase/synthase [Escherichia coli K12]
Length = 309
Score = 168 bits (422), Expect = 6e-41
Identities = 95/292 (32%), Positives = 164/292 (55%), Gaps = 4/292 (1%)
Query: 3 GVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEKG 62
G+I P+ T F D +D I L + GV G+F + GEF+ L +ERK +A
Sbjct: 16 GIIPPVSTIFTADGQLDKPGTAALIDDLIKAGVDGLFFLGSGGEFSQLGAEERKAIARFA 75
Query: 63 REITSGMY--LVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMVA 120
+ L+GTG T+ E IELS+HA+ GADGIV++ PYY K+ + ++++F VA
Sbjct: 76 IDHVDRRVPVLIGTGGTNARETIELSQHAQQAGADGIVVINPYYWKVSEANLIRYFEQVA 135
Query: 121 ERVDIPIIVYAIPS-CANPVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIE-VKEERK 178
+ V +P+++Y P+ + +++ ++ SNIIG+K ++DS+ +L+ +I VK
Sbjct: 136 DSVTLPVMLYNFPALTGQDLTPALVKTLADSRSNIIGIKDTIDSVAHLRSMIHTVKGAHP 195
Query: 179 DFRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRVLGEI 238
F V G D + +TLLLGGDG I A NFAP++ + + +++ + +A + L +I
Sbjct: 196 HFTVLCGYDDHLFNTLLLGGDGAISASGNFAPQVSVNLLKAWRDGDVAKAAGYHQTLLQI 255
Query: 239 SRIYNVASSFASAVKLAMIAKGFPIKPVLRPPHVIDGEEVFNEIKGILRSLE 290
++Y + + F + +K A++ G P+ + PP E ++K +L+ L+
Sbjct: 256 PQMYQLDTPFVNVIKEAIVLCGRPVSTHVLPPASPLDEPRKAQLKTLLQQLK 307
>gb|AAK42436.1| Dihydrodipicolinate synthase (dapA-1) [Sulfolobus solfataricus]
Length = 289
Score = 155 bits (387), Expect = 7e-37
Identities = 92/291 (31%), Positives = 163/291 (55%), Gaps = 6/291 (2%)
Query: 1 MEGVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAE 60
M+ I LVTP+ + +I+ EAL+ + FL +KG+ +V T+GEF L+ DER ++
Sbjct: 1 MKENISALVTPYDDKENINTEALQQLLDFLIKKGIKDFWVLGTSGEFNMLSQDERILVVS 60
Query: 61 KGREITSGMYLVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMVA 120
K RE+ G VG ST + L++ D+G D I V P Y K ++ ++ +FS +
Sbjct: 61 KIREMVKGKIYVGVNENSTRNSLILAKKYYDLGVDYIFSVPPIYHKPSEKGLISYFSELR 120
Query: 121 ERVDIPIIVYAIPSCAN-PVPVDIIRKVSLEYSNIIGVK-ASVDSLTYLQELIEVKEERK 178
+D+P+ +Y IPS VP+ II K++ EY + G+K ++ D +++L+ L +K K
Sbjct: 121 NAIDLPLFIYNIPSFTGYNVPLHIIEKLAREYV-LDGMKYSTTDFVSFLKYLKALKGVNK 179
Query: 179 DFRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRVLGEI 238
+F+VF G D+ LS L+L DG + +N PE+ ++ F R N + AI++ R+L ++
Sbjct: 180 NFKVFIGEDRMILSALILDTDGAVSGISNLVPELVTNLFLEFDRGNIQRAIEIQRILNKL 239
Query: 239 SRIYNVASSFASAVKLAMIAKGFPIKPVLRPPHVIDGEEVFNEIKGILRSL 289
+ ++ + S +K+ + +G + V +P +++ EI +L+ L
Sbjct: 240 VDVVSL-GDYPSGIKIGLRYRGINVGSVRKP--LLEDSRAEGEIYNVLKEL 287
>gi|11498515 dihydrodipicolinate synthase (dapA) [Archaeoglobus fulgidus]
>gi|6014905|sp|O29352|DAPA_ARCFU DIHYDRODIPICOLINATE
SYNTHASE (DHDPS) >gi|7436668|pir||F69363
dihydrodipicolinate synthase (EC 4.2.1.52) AF0910
[similarity] - Archaeoglobus fulgidus
>gi|2649690|gb|AAB90330.1| (AE001041)
dihydrodipicolinate synthase (dapA) [Archaeoglobus
fulgidus]
Length = 289
Score = 145 bits (361), Expect = 8e-34
Identities = 99/294 (33%), Positives = 158/294 (53%), Gaps = 15/294 (5%)
Query: 2 EGVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEK 61
EGVI +VTPF+ED+S+D+E + ++ +LE K V+ + TTGE +L+ +E +
Sbjct: 3 EGVIPAMVTPFKEDFSVDYEGIAKNLDYLE-KHVNALVPAGTTGEAATLSYEEHIDVVRY 61
Query: 62 GREITSGMYLVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMVAE 121
E + + G GS ST E I L++ E GA+ ++V PYY K E + +H+ VA
Sbjct: 62 VAETSKLPVIGGAGSNSTREAIWLAKEVEKAGAEAAMLVTPYYNKPNAEGLYQHYKAVAS 121
Query: 122 RVDIPIIVYAIPSCA--NPVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEERKD 179
V IPIIVY +PS N P +++R+++ E NI G+K + +L + E+I + D
Sbjct: 122 EVSIPIIVYNVPSRTGINTTP-ELVRRLA-EIDNIFGIKEASGNLKQISEIIRTTPD--D 177
Query: 180 FRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRVLGEIS 239
F + +G D L L LGG G I AN AP + +++ +F N E A ++ L +
Sbjct: 178 FVLLSGDDFLTLPILCLGGKGVISVAANVAPHLMKEMYEAFVEGNIERAREMHHRLTPLF 237
Query: 240 RIYNVASS---FASAVKLAMIAKGFPIKPVLRPPHVIDGEEVFNEIKGILRSLE 290
+ + ++ A++L +A G P R P V EE ++K +L+SLE
Sbjct: 238 DVLFIDTNPIPVKKALQLMGLAAGKP-----RLPLVELSEEKTQKVKEVLKSLE 286
>sp|Q57695|DAPA_METJA DIHYDRODIPICOLINATE SYNTHASE (DHDPS) >gi|2127847|pir||E64330
dihydrodipicolinate synthase (EC 4.2.1.52) -
Methanococcus jannaschii >gi|1590977|gb|AAB98232.1|
(U67480) dihydrodipicolinate synthase (dapA)
[Methanococcus jannaschii]
Length = 289
Score = 144 bits (360), Expect = 1e-33
Identities = 99/291 (34%), Positives = 156/291 (53%), Gaps = 10/291 (3%)
Query: 2 EGVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEK 61
+GV ++TPF+ +DF+ LE +I FL E GV GI TTGE +L+ +E K + EK
Sbjct: 3 KGVYPAIITPFKNK-EVDFDGLEENINFLIENGVSGIVAVGTTGESPTLSHEEHKKVIEK 61
Query: 62 GREITSG--MYLVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMV 119
++ +G + G GS T E IELS AED+GAD ++ + PYY K E + KHF V
Sbjct: 62 VVDVVNGRVQVIAGAGSNCTEEAIELSVFAEDVGADAVLSITPYYNKPTQEGLRKHFGKV 121
Query: 120 AERVDIPIIVYAIPS-CANPVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEERK 178
AE +++PI++Y +PS A + ++ ++ EYSNI VK + +L+ + ELI +
Sbjct: 122 AESINLPIVLYNVPSRTAVNLEPKTVKLLAEEYSNISAVKEANPNLSQVSELIHDAK--- 178
Query: 179 DFRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRVLGEI 238
V +G D+ L + LGG G I AN P+ +++ N +FE+A ++ L +
Sbjct: 179 -ITVLSGNDELTLPIIALGGKGVISVVANIVPKEFVEMVNYALEGDFEKAREIHYKLFPL 237
Query: 239 SRIYNVASSFASAVKLAMIAKGFPIKPVLRPPHVIDGEEVFNEIKGILRSL 289
+ + ++ VK A+ G P LR P EE ++ +L+ L
Sbjct: 238 MKAMFIETN-PIPVKTALNMMGRPAGE-LRLPLCEMSEEHKKILENVLKDL 286
>sp|Q9X1K9|DAPA_THEMA DIHYDRODIPICOLINATE SYNTHASE (DHDPS) >gi|7436673|pir||B72246
dihydrodipicolinate synthase (EC 4.2.1.52) TM1521
[similarity] - Thermotoga maritima (strain MSB8)
>gi|4982087|gb|AAD36588.1|AE001799_20 (AE001799)
dihydrodipicolinate synthase [Thermotoga maritima]
Length = 294
Score = 143 bits (356), Expect = 3e-33
Identities = 89/290 (30%), Positives = 159/290 (54%), Gaps = 9/290 (3%)
Query: 3 GVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEKG 62
GV +VTPF+ +D E+ E +R+ E GV+ + V TTGE ++N DER+ L +
Sbjct: 4 GVGTAIVTPFKNG-ELDLESYERLVRYQLENGVNALIVLGTTGESPTVNEDEREKLVSRT 62
Query: 63 REITSGMY--LVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMVA 120
EI G +VG G+ ST + ++L + AE +GA+G+++V PYY K E + +H+ ++
Sbjct: 63 LEIVDGKIPVIVGAGTNSTEKTLKLVKQAEKLGANGVLVVTPYYNKPTQEGLYQHYKYIS 122
Query: 121 ERVDIPIIVYAIP--SCANPVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEV-KEER 177
ER D+ I+VY +P + N +P + +++ + N++G+K + + + + + K+ R
Sbjct: 123 ERTDLGIVVYNVPGRTGVNVLP-ETAARIAADLKNVVGIKEANPDIDQIDRTVSLTKQAR 181
Query: 178 KDFRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRVLGE 237
DF V++G D L GGDG I +N AP+ +++ + N E++ ++ R L
Sbjct: 182 SDFMVWSGNDDRTFYLLCAGGDGVISVVSNVAPKQMVELCAEYFSGNLEKSREVHRKLRP 241
Query: 238 ISRIYNVASSFASAVKLAMIAKGFPIKPVLRPPHVIDGEEVFNEIKGILR 287
+ + V ++ VK A+ GF I+ LR P V E+ ++ +L+
Sbjct: 242 LMKALFVETN-PIPVKAALNLMGF-IENELRLPLVPASEKTVELLRNVLK 289
>sp|O67216|DAPA_AQUAE DIHYDRODIPICOLINATE SYNTHASE (DHDPS) >gi|7436663|pir||E70398
dihydrodipicolinate synthase (EC 4.2.1.52) dapA
[similarity] - Aquifex aeolicus
>gi|2983599|gb|AAC07169.1| (AE000725)
dihydrodipicolinate synthase [Aquifex aeolicus]
Length = 294
Score = 130 bits (323), Expect = 2e-29
Identities = 83/244 (34%), Positives = 129/244 (52%), Gaps = 8/244 (3%)
Query: 2 EGVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEK 61
+G IV L+TPF+E +D+EAL I F + G I V TTGE +L +E + + E
Sbjct: 3 QGSIVALITPFKEG-EVDYEALGNLIEFHVDNGTDAILVCGTTGESPTLTFEEHEKVIEF 61
Query: 62 GREITSGMYLV--GTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMV 119
+ +G V GTG +T E + L+ HA+++GADG ++V PYY K + +HF V
Sbjct: 62 AVKRAAGRIKVIAGTGGNATHEAVHLTAHAKEVGADGALVVVPYYNKPTQRGLYEHFKTV 121
Query: 120 AERVDIPIIVYAIPS--CANPVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEER 177
A+ VDIPII+Y IPS C + VD + K++ E NI+ K S ++ + E+ VK
Sbjct: 122 AQEVDIPIIIYNIPSRTCVE-ISVDTMFKLASECENIVASKESTPNMDRISEI--VKRLG 178
Query: 178 KDFRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRVLGE 237
+ F V +G D L + LG G I N P ++ + +F A ++ L +
Sbjct: 179 ESFSVLSGDDSLTLPMMALGAKGVISVANNVMPREVKELIRAALEGDFRRAREIHYYLHD 238
Query: 238 ISRI 241
+ ++
Sbjct: 239 LFKV 242
>pir||D81393 probable lyase Cj0481 [imported] - Campylobacter jejuni (strain
NCTC 11168) >gi|6967952|emb|CAB75119.1| (AL139075)
putative lyase [Campylobacter jejuni]
Length = 302
Score = 127 bits (317), Expect = 1e-28
Identities = 78/296 (26%), Positives = 157/296 (52%), Gaps = 10/296 (3%)
Query: 1 MEGVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAE 60
++G + L+TP+++D SI+ + + F KG++G+F N + G+ +L+ +E+ L +
Sbjct: 4 LKGTLPALLTPYKDDGSINEKEFIRYCEFGISKGLNGLFCNGSAGDSQALSVEEQVKLMK 63
Query: 61 KGREITSGMYLVGTGSTSTL--EVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSM 118
++ T + TG TST+ L++ A ++G D +++ PYY KL ++ + ++
Sbjct: 64 LTKKATKNNIPIITGITSTIYENTFILAQKAYELGLDALLLAMPYYYKLSEDALFEYVKY 123
Query: 119 VAERVDIPIIVYAIPSCANPVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEERK 178
+A V +P+ VY IP A + + I KVS + N++G+K S L +++V
Sbjct: 124 LASEVKLPLYVYNIPLFAPALSLKFIEKVS-KLDNVVGIKDSSGDALLLNHILDVVP--S 180
Query: 179 DFRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRVLGEI 238
+F VF G +++++ LL G G + + PE+ +I+ S +N A+ + + L +
Sbjct: 181 NFDVFVGREEFYVGALLAGVKGSMTSIGGVFPELMSEIYKSINEKNIGRALLIQKSLLKA 240
Query: 239 SRIYNVASSFASAVKLAMIAKGFP-IKPVLRPPHVIDGEEV---FNEIKGILRSLE 290
R + ++ +F L + A+GF + + P EE+ F+E K +++++E
Sbjct: 241 IR-FGMSIAFPMGFALLLKARGFEFVNASIHPLSPATKEELNTRFDEAKELIKTIE 295
>emb|CAC12282.1| (AL445066) dihydrodipicoline synthase related protein [Thermoplasma
acidophilum]
Length = 292
Score = 127 bits (316), Expect = 2e-28
Identities = 73/232 (31%), Positives = 125/232 (53%), Gaps = 5/232 (2%)
Query: 2 EGVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEK 61
+G++ P++TP ++ ID+ A E I L + GV G+F +TG F +TDE+K
Sbjct: 3 KGIVTPMITPMGQNGEIDYRATEILIDNLADFGVDGLFPMGSTGLFPMFSTDEKKKFLGF 62
Query: 62 GREITSGMYL-VGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMVA 120
R+ + + + G GS+ST E +ELS++ EDIG V++ YY K ++ + +HFS V
Sbjct: 63 VRDHSKKIEVYAGVGSSSTQESVELSKYTEDIGIKVRVLMPTYYIKPDEDWMYRHFSTVI 122
Query: 121 ERVDIPIIVYAIPSCANP-VPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEERKD 179
+ +Y IP + + +I K++ E+SN+ G+K S + + +I K E+
Sbjct: 123 SAASNDLFIYNIPQLSGSWISESLIEKLTREFSNVKGIKDSSGDMRFFSRIIRHKNEK-- 180
Query: 180 FRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKL 231
F +F G D +L +G GG+ +N +P I +++ F N E+A K+
Sbjct: 181 FDIFQGQDDLLFLSLSIGASGGVCGLSNISPYI-TNLYHEFSAGNLEKARKI 231
>dbj|BAB05461.1| (AP001513) dihydrodipicolinate synthase [Bacillus halodurans]
Length = 295
Score = 126 bits (313), Expect = 3e-28
Identities = 87/277 (31%), Positives = 135/277 (48%), Gaps = 7/277 (2%)
Query: 4 VIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEKGR 63
++ +VTPF E ++ EA + L G + V TTGE +L TDE+ L
Sbjct: 6 IVTAMVTPFNEQDQVNLEATCQLVNELIANGSDALVVGGTTGESPTLTTDEKMALFHTVV 65
Query: 64 EITSGMY--LVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMVAE 121
E G + GTGS +T IELS+ ED+G DGI++V PYY K E + +HF ++E
Sbjct: 66 EAAGGRVPVIAGTGSNNTRASIELSKKVEDLGVDGIMLVTPYYNKPSQEGLFQHFKAISE 125
Query: 122 RVDIPIIVYAIPSCANPVPVDIIRKVSL-EYSNIIGVKASVDSLTYLQELIEVKEERKDF 180
+PI++Y IP + V +D + L E NI+ +K + +L + E+IE DF
Sbjct: 126 STSLPIMLYNIPG-RSGVNLDAETTLRLAELRNIVSIKEASGNLDQIAEIIE--HSPADF 182
Query: 181 RVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRVLGEISR 240
V++G D L L +GG G + ++ ++ F E A + R L + +
Sbjct: 183 SVYSGDDSLTLPLLSIGGTGVVSVASHIIGNEMQEMVQLFLSGQVERAAAIHRKLLPLMK 242
Query: 241 IYNVASSFASAVKLAMIAKGFPIKPVLRPPHVIDGEE 277
+ + +AVK A+ KG P+ V P + EE
Sbjct: 243 TLFMTPN-PTAVKAALELKGLPVGHVRLPLVPLTAEE 278
>sp|O26892|DAPA_METTH DIHYDRODIPICOLINATE SYNTHASE (DHDPS) >gi|7436662|pir||A69207
dihydrodipicolinate synthase (EC 4.2.1.52) MTH801
[similarity] - Methanobacterium thermoautotrophicum
(strain Delta H) >gi|2621891|gb|AAB85301.1| (AE000858)
dihydrodipicolinate synthase [Methanobacterium
thermoautotrophicum]
Length = 283
Score = 126 bits (313), Expect = 3e-28
Identities = 77/253 (30%), Positives = 137/253 (53%), Gaps = 8/253 (3%)
Query: 1 MEGVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAE 60
+EG +V +VTPF ED +D L +I +L E GV G+ V TTGE ++ +E++ + +
Sbjct: 3 IEGTVVAMVTPFTEDDVVDEAGLRENINYLIENGVDGLLVAGTTGESATITHEEQRRMID 62
Query: 61 KGREITSGMY--LVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSM 118
+ +G + G GS S+ E + L +AED GAD +++ PYY K + +++H++M
Sbjct: 63 ILVDEVNGRVRTVAGAGSNSSREAMGLVEYAEDAGADAALVITPYYNKPQPHGLIEHYTM 122
Query: 119 VAERVDIPIIVYAIPS-CANPVPVDIIRKVSLEYSNIIGVKAS---VDSLTYLQELIEVK 174
+ E DIP+I+Y +PS + VD + +++ + IIG+K + +D ++ L+ + +
Sbjct: 123 LEEAADIPLIIYNVPSRTGTDIDVDTVAELA-KLDGIIGIKEASPDLDKVSMLRSRL-MD 180
Query: 175 EERKDFRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRV 234
DF V +G D L + +G +G I AN P ++ N +FE A+K
Sbjct: 181 LGLDDFTVLSGNDNLTLPMISMGAEGVISVVANVDPARMSRLVNEALSGDFESAMKTHYE 240
Query: 235 LGEISRIYNVASS 247
L + ++ + S+
Sbjct: 241 LYSLMKVLFIESN 253
>gb|AAG18989.1| (AE004999) dihydrodipicolinate synthase; DapA [Halobacterium sp.
NRC-1]
Length = 313
Score = 125 bits (311), Expect = 6e-28
Identities = 83/283 (29%), Positives = 137/283 (48%), Gaps = 14/283 (4%)
Query: 1 MEGVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLA- 59
+ GV+ P+VT F D S+D + H R + + GVHG+F T GEF L ER +
Sbjct: 25 LHGVVPPVVTAFDADESLDADTTADHARMVVDAGVHGVFPLGTNGEFPLLTPSERDRVVT 84
Query: 60 ----EKGREITSGMYLVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKH 115
E G E+ + G G+ ST + + + HA +GADG+V+V P+Y L ++H
Sbjct: 85 AVVDEVGGEVP---VIAGVGAPSTRQTVAHAEHAASVGADGVVVVTPFYYPLDGTAAVEH 141
Query: 116 FSMVAERVDIPIIVYAIPS-CANPVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVK 174
+ VA VD P+ VY IPS N + ++ + ++ E + GVK S + +L + ++
Sbjct: 142 YRRVAAAVDCPVYVYHIPSKTGNELSLETLAALA-EIDTLAGVKDSSKDVPWLGQAVDAH 200
Query: 175 EERKDFRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRV 234
E G D L +G G + A AN APE+ + ++ ++ + E A
Sbjct: 201 PE---LTFLAGSDSLLAPGLDVGCAGLVSAVANVAPELVVGLYEAYDEGDRERARARQST 257
Query: 235 LGEISRIYNVASSFASAVKLAMIAKGFPIKPVLRPPHVIDGEE 277
+ E+ R + + VK A+ +GF P+ P +D ++
Sbjct: 258 VYEV-RAALKRGPYMAGVKAALGLRGFDAGPLRSPLRGLDDDD 299
>sp|Q07607|MOSA_RHIME MOSA PROTEIN >gi|1073154|pir||B53308 mosA protein - Rhizobium
meliloti (strain L5-30) >gi|310303|gb|AAA26301.1|
(L17071) mosA [Sinorhizobium meliloti]
Length = 333
Score = 120 bits (299), Expect = 2e-26
Identities = 87/253 (34%), Positives = 128/253 (50%), Gaps = 6/253 (2%)
Query: 2 EGVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEK 61
EG I LVTPF +D ID AL + + E+G G+ TTGE +L+ E + + E
Sbjct: 3 EGSITALVTPFADD-RIDEVALHDLVEWQIEEGSFGLVPCGTTGESPTLSKSEHEQVVEI 61
Query: 62 GREITSGMY--LVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMV 119
+ +G + G GS ST E I RHA++ GADG++IV+PYY K E I +HF +
Sbjct: 62 TIKTANGRVPVIAGAGSNSTAEAIAFVRHAQNAGADGVLIVSPYYNKPTQEGIYQHFKAI 121
Query: 120 AERVDIPIIVYAIPS-CANPVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEERK 178
IPIIVY IP A + V+ + ++ + N+ GVK + +L L+ +E +
Sbjct: 122 DAASTIPIIVYNIPGRSAIEIHVETLARIFEDCPNVKGVKDATGNL--LRPSLERMACGE 179
Query: 179 DFRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRVLGEI 238
DF + TG D L + GG G I AN AP + + +F A+KL L +
Sbjct: 180 DFNLLTGEDGTALGYMAHGGHGCISVTANVAPALCADFQQACLNGDFAAALKLQDRLMPL 239
Query: 239 SRIYNVASSFASA 251
R + ++ A A
Sbjct: 240 HRALFLETNPAGA 252
>sp|Q9ZM13|DAPA_HELPJ DIHYDRODIPICOLINATE SYNTHASE (DHDPS) >gi|7436664|pir||C71935
dihydrodipicolinate synthase (EC 4.2.1.52) dapA
[similarity] - Helicobacter pylori (strain J99)
>gi|4154941|gb|AAD05987.1| (AE001475)
DIHYDRODIPICOLINATE SYNTHASE [Helicobacter pylori J99]
Length = 300
Score = 116 bits (288), Expect = 3e-25
Identities = 82/293 (27%), Positives = 140/293 (46%), Gaps = 14/293 (4%)
Query: 8 LVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEKGREITS 67
L+TPF++D S+D A E I+ +G+ TTGE +L E E E
Sbjct: 9 LITPFKKDLSVDEAAYETLIKRQIFQGMDACVPVGTTGESATLTHKEHMRCIEIAIETCK 68
Query: 68 GM---------YLVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSM 118
L G GS +T E + L++ A+ IGAD I+ V+PYY + + + +H+
Sbjct: 69 STKTPSNSRMKVLAGVGSNATSESLSLAKFAQKIGADAILCVSPYYNRPTQQGLFEHYKT 128
Query: 119 VAERVDIPIIVYAIPSCAN-PVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEER 177
+A+ V+IP+++Y +PS + V K+ E NI +K + S L+ + E+
Sbjct: 129 IAQSVEIPVMLYDVPSRTGVSIEVPTALKLFREVPNIKAIKEASGS---LKRVTELHYYE 185
Query: 178 KDFRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRVLGE 237
KDF++F+G D S + GG G I N P + Q+ N + +++A+++ L +
Sbjct: 186 KDFKIFSGEDSLNHSIMFSGGCGVISVTGNLMPNLISQMVNCALKFEYQQALEIQNKLFD 245
Query: 238 ISRIYNVASSFASAVKLAMIAKGFPIKPVLRPPHVIDGEEVFNEIKGILRSLE 290
+ + V ++ +K+AM G P R P V +E ++ L+ E
Sbjct: 246 LHQALFVETN-PIPIKMAMHLAGLIENPSYRLPLVAPSKETIKLLEKTLQQYE 297
>sp|O25657|DAPA_HELPY DIHYDRODIPICOLINATE SYNTHASE (DHDPS) >gi|7436661|pir||E64646
dihydrodipicolinate synthase (EC 4.2.1.52) HP1013
[similarity] - Helicobacter pylori (strain 26695)
>gi|2314156|gb|AAD08057.1| (AE000609)
dihydrodipicolinate synthetase (dapA) [Helicobacter
pylori 26695]
Length = 300
Score = 115 bits (286), Expect = 5e-25
Identities = 82/293 (27%), Positives = 140/293 (46%), Gaps = 14/293 (4%)
Query: 8 LVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEKGREITS 67
L+TPF++D S+D A E I+ +G+ TTGE +L E E E
Sbjct: 9 LITPFKKDLSVDEAAYETLIKRQIFQGMDACVPVGTTGESATLTHKEHMRCIEIAIETCK 68
Query: 68 GM---------YLVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSM 118
L G GS +T E + L++ A+ IGAD I+ V+PYY + + + +H+
Sbjct: 69 NTKTPSNSRMKVLAGVGSNATSESLSLAKFAQKIGADAILCVSPYYNRPTQQGLFEHYKT 128
Query: 119 VAERVDIPIIVYAIPSCAN-PVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEER 177
+A+ V+IP+++Y +PS + V K+ E NI +K + S L+ + E+
Sbjct: 129 IAQSVEIPVMLYDVPSRTGVSIEVPTALKLFREVPNIKAIKEASGS---LKRVTELHYYE 185
Query: 178 KDFRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRVLGE 237
KDF++F+G D S + GG G I N P + Q+ N ++ +++A+++ L
Sbjct: 186 KDFKIFSGEDSLNHSIMFSGGCGVISVTGNLMPNLISQMVNCALKQKYQQALEIQNKLFC 245
Query: 238 ISRIYNVASSFASAVKLAMIAKGFPIKPVLRPPHVIDGEEVFNEIKGILRSLE 290
+ + V ++ +K+AM G P R P V +E ++ L+ E
Sbjct: 246 LHQALFVETN-PIPIKMAMHLAGLIENPSYRLPLVAPSKETIQLLEKTLQQYE 297
>gb|AAK43294.1| 2-keto-3-deoxy gluconate aldolase (eda) [Sulfolobus solfataricus]
Length = 308
Score = 115 bits (284), Expect = 9e-25
Identities = 79/297 (26%), Positives = 145/297 (48%), Gaps = 11/297 (3%)
Query: 1 MEGVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAE 60
M +I P++TPF +D ID E L+ H L KG+ +FVN TTG SL+ +E+ +
Sbjct: 15 MPEIITPIITPFTKDNRIDKEKLKIHAENLIRKGIDKLFVNGTTGLGPSLSPEEKLENLK 74
Query: 61 KGREITSGMYLVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYC-KLKDEEILKHFSMV 119
++T+ + + G + + I L++ ++D GI APYY ++ ++ ++K+F +
Sbjct: 75 AVYDVTNKI-IFQVGGLNLDDAIRLAKLSKDFDIVGIASYAPYYYPRMSEKHLVKYFKTL 133
Query: 120 AERVDIPIIVYAIPSCANPVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEERKD 179
E P+ +Y P+ DI KV+ E GVK +++++ + ++ K +
Sbjct: 134 CEVSPHPVYLYNYPTATGK---DIDAKVAKEIGCFTGVKDTIENIIH---TLDYKRLNPN 187
Query: 180 FRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRVLGEIS 239
V++G D + G DG + A +N+ PE+ + I R +EA+KL + E+
Sbjct: 188 MLVYSGSDMLIATVASTGLDGNVAAGSNYLPEVTVTIKKLAMERKIDEALKLQFLHDEVI 247
Query: 240 RIYNVASSFASAVKLAMIAKGFPIKPVLRPPHVIDGEE---VFNEIKGILRSLENVK 293
+ S +S L +G+ + P +D EE + +++GI L +K
Sbjct: 248 EASRIFGSLSSNYVLTKYFQGYDLGYPRPPIFPLDDEEERQLIKKVEGIRAKLVELK 304
>emb|CAA11866.1| (AJ224174) 2-keto-3-deoxy gluconate aldolase [Sulfolobus
solfataricus]
Length = 294
Score = 115 bits (284), Expect = 9e-25
Identities = 79/297 (26%), Positives = 145/297 (48%), Gaps = 11/297 (3%)
Query: 1 MEGVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAE 60
M +I P++TPF +D ID E L+ H L KG+ +FVN TTG SL+ +E+ +
Sbjct: 1 MPEIITPIITPFTKDNRIDKEKLKIHAENLIRKGIDKLFVNGTTGLGPSLSPEEKLENLK 60
Query: 61 KGREITSGMYLVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYC-KLKDEEILKHFSMV 119
++T+ + + G + + I L++ ++D GI APYY ++ ++ ++K+F +
Sbjct: 61 AVYDVTNKI-IFQVGGLNLDDAIRLAKLSKDFDIVGIASYAPYYYPRMSEKHLVKYFKTL 119
Query: 120 AERVDIPIIVYAIPSCANPVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEERKD 179
E P+ +Y P+ DI KV+ E GVK +++++ + ++ K +
Sbjct: 120 CEVSPHPVYLYNYPTATGK---DIDAKVAKEIGCFTGVKDTIENIIH---TLDYKRLNPN 173
Query: 180 FRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRVLGEIS 239
V++G D + G DG + A +N+ PE+ + I R +EA+KL + E+
Sbjct: 174 MLVYSGSDMLIATVASTGLDGNVAAGSNYLPEVTVTIKKLAMERKIDEALKLQFLHDEVI 233
Query: 240 RIYNVASSFASAVKLAMIAKGFPIKPVLRPPHVIDGEE---VFNEIKGILRSLENVK 293
+ S +S L +G+ + P +D EE + +++GI L +K
Sbjct: 234 EASRIFGSLSSNYVLTKYFQGYDLGYPRPPIFPLDDEEERQLIKKVEGIRAKLVELK 290
>pir||C83520 dihydrodipicolinate synthase PA1010 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9946920|gb|AAG04399.1|AE004533_10 (AE004533)
dihydrodipicolinate synthase [Pseudomonas aeruginosa]
Length = 292
Score = 114 bits (282), Expect = 1e-24
Identities = 77/214 (35%), Positives = 114/214 (52%), Gaps = 12/214 (5%)
Query: 3 GVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEKG 62
G +V LVTPF +D+++L + F ++G + I TTGE +L+ +E + +
Sbjct: 4 GSMVALVTPFDAQGRLDWDSLAKLVDFHLQEGTNAIVAVGTTGESATLDVEEHIQVIRRV 63
Query: 63 REITSGMY--LVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMVA 120
+ G + GTG+ ST E + L+ A+ GAD ++V PYY K E + +HF +A
Sbjct: 64 VDQVKGRIPVIAGTGANSTREAVALTEAAKSGGADACLLVTPYYNKPTQEGMYQHFRHIA 123
Query: 121 ERVDIPIIVYAIP---SC-ANPVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEE 176
E V IP I+Y +P SC P V+ + KV NIIG+K + L +E+IE
Sbjct: 124 EAVAIPQILYNVPGRTSCDMLPETVERLSKV----PNIIGIKEATGDLQRAKEVIE--RV 177
Query: 177 RKDFRVFTGLDQYFLSTLLLGGDGGIMACANFAP 210
KDF V++G D + +LLGG G I AN AP
Sbjct: 178 GKDFLVYSGDDATAVELMLLGGKGNISVTANVAP 211
>pir||D81141 dihydrodipicolinate synthase NMB0929 [imported] - Neisseria
meningitidis (group B strain MD58)
>gi|7226167|gb|AAF41336.1| (AE002444)
dihydrodipicolinate synthase [Neisseria meningitidis
MC58]
Length = 291
Score = 113 bits (281), Expect = 2e-24
Identities = 79/219 (36%), Positives = 115/219 (52%), Gaps = 14/219 (6%)
Query: 1 MEGVIVPLVTPFREDYSIDFEAL----EWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERK 56
++G +V L+TP +D SI +E L +WHI E G GI TTGE +L+ +E
Sbjct: 2 LQGSLVALITPMNQDGSIHYEQLRDLIDWHI----ENGTDGIVAVGTTGESATLSVEEHT 57
Query: 57 MLAEKGREITSGMY--LVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILK 114
+ E + + + GTG+ +T+E I LS+ AE GAD + V PYY K E I +
Sbjct: 58 AVIEAVVKHVAKRVPVIAGTGANNTVEAIALSQAAEKAGADYTLSVVPYYNKPSQEGIYQ 117
Query: 115 HFSMVAERVDIPIIVYAIPS-CANPVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEV 173
HF +AE IP+I+Y +P + D I +++ E NI+GVK + ++ ELI
Sbjct: 118 HFKTIAEATSIPMIIYNVPGRTVVSMTNDTILRLA-EIPNIVGVKEASGNIGSNIELINR 176
Query: 174 KEERKDFRVFTGLDQYFLSTLLLGGDGGIMACANFAPEI 212
E F V +G D L +L GG G I AN AP++
Sbjct: 177 APE--GFVVLSGDDHTALPFMLCGGHGVITVAANAAPKL 213
>gb|AAF04320.1| (AF065159) dihydrodipicolinate synthase [Bradyrhizobium japonicum]
Length = 296
Score = 112 bits (277), Expect = 6e-24
Identities = 88/284 (30%), Positives = 137/284 (47%), Gaps = 23/284 (8%)
Query: 3 GVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEKG 62
G LVTPF+ S+D A + + +G +G+ TTGE +L+ DE K + E
Sbjct: 9 GSFTALVTPFKNG-SLDEAAFRSLVNWQISEGTNGLVPVGTTGESPTLSHDEHKKVVEWC 67
Query: 63 REITSGMYLV--GTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMVA 120
E G V G GS ST E IEL++HAE GAD +++V PYY K E + +HF +
Sbjct: 68 IEEAKGRVPVVAGAGSNSTKEAIELAQHAEKAGADAVLVVTPYYNKPTQEGMYQHFKAIN 127
Query: 121 ERVDIPIIVYAI-PSCANPVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEER-- 177
+ + IPII+Y I P + VD ++++ E NI GVK + S ++ V ++R
Sbjct: 128 DAIGIPIIIYNIPPRSVIDMSVDTMKRL-WELKNIAGVKDATAS------MVRVSQQRAA 180
Query: 178 --KDFRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRVL 235
+DF +G L + G G I +N AP + + ++++ + A+KL L
Sbjct: 181 MGEDFNQLSGEVATILGYMAQCGHGCISVTSNVAPRLCSEFHTAWQKGDQRTALKLHDKL 240
Query: 236 GEISRIYNVASSFASAVKLAMIAKG-------FPIKPVLRPPHV 272
+ + S+ + +K AM G P+ PV P V
Sbjct: 241 MPVHNNLFIESN-PAPIKYAMSLLGKLDETLRLPMVPVTEPTRV 283
>dbj|BAB06118.1| (AP001515) dihydrodipicolinate synthase [Bacillus halodurans]
Length = 292
Score = 111 bits (275), Expect = 1e-23
Identities = 82/269 (30%), Positives = 131/269 (48%), Gaps = 7/269 (2%)
Query: 4 VIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEKGR 63
V+ +VTPF ++D E +E + FL G G+ V TTGE +L +E+ L EK
Sbjct: 6 VLTAMVTPFDAKGNVDLEKVERLVEFLLANGTEGLVVAGTTGESPTLREEEKLALFEKVV 65
Query: 64 EITSGMY--LVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMVAE 121
+ + + GTGS +T +L++ A +G DGI+ V PYY K E + HF+ +AE
Sbjct: 66 TVVNKRVPVIAGTGSNNTYVSAQLTKKATALGVDGIMAVTPYYNKPSQEGMYAHFAAIAE 125
Query: 122 RVDIPIIVYAIPSCANPVPVDIIRKVSLEY-SNIIGVKASVDSLTYLQELIEVKEERKDF 180
+P+++Y IPS + V + V L Y NI +K + L ++ +IE + F
Sbjct: 126 ATHLPVMLYNIPS-RSVVNLSAETIVKLSYIPNITSLKEANGDLDHMVSVIE--QTPDTF 182
Query: 181 RVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRVLGEISR 240
+++G D L L +G G + ++ Q+ +F+ + E A L R L I +
Sbjct: 183 HLYSGDDSLTLPALSIGAKGVVSVASHIIGPEMQQMMMAFRGGDVEHAANLHRKLLPIMK 242
Query: 241 IYNVASSFASAVKLAMIAKGFPIKPVLRP 269
A + + VK A+ KGF V P
Sbjct: 243 GLFTAPN-PTCVKAALQIKGFDTGGVRLP 270
>gb|AAK43137.1| Dihydrodipicolinate synthase (dapA-2) [Sulfolobus solfataricus]
Length = 302
Score = 111 bits (274), Expect = 1e-23
Identities = 76/273 (27%), Positives = 141/273 (50%), Gaps = 6/273 (2%)
Query: 1 MEGVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDER-KMLA 59
M+GV + VTPF + +D E L+ + F + G I T GEF+SL +E+ +++
Sbjct: 1 MDGVFLTNVTPFTKTLELDLEGLKRIVEFAQNSGYKYIVPLGTAGEFSSLTVEEKVRVVD 60
Query: 60 EKGREITSGMYLVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMV 119
R ++ G + G STS LE EL + ++IG D I+++ PYY K ++ ++++F V
Sbjct: 61 HVRRALSKGEIIAGASSTSFLETGELCKKYKEIGVDKIMVLPPYYLKGNEKGLMEYFFKV 120
Query: 120 AERVDIPIIVYAIPSCAN-PVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEERK 178
AE D +++Y PS + +I++++ + +K + ++ +E++ + ++
Sbjct: 121 AELCDSTMVLYNNPSSTGVDLSPQLIKRLNDMIPSFRVLKEARYNVVEFKEVVRLVGDKI 180
Query: 179 DFRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSF-KRRNFEEAIKLSRVLGE 237
D V GL++ L L+LG G + +F+ + L I+ S+ K+RN + AI+L +L E
Sbjct: 181 D--VIDGLEERALLGLVLGAKGFTTSMGSFS-SLPLMIYESYEKKRNIDTAIRLYDLLLE 237
Query: 238 ISRIYNVASSFASAVKLAMIAKGFPIKPVLRPP 270
+ + + KL +G RPP
Sbjct: 238 YRSFIKLPLTMSHLAKLGAWLRGLISSYATRPP 270
>sp|Q04796|DAPA_BACSU DIHYDRODIPICOLINATE SYNTHASE (DHDPS) (VEGETATIVE PROTEIN 81)
(VEG81) >gi|538924|pir||E46665 dihydrodipicolinate
synthase (EC 4.2.1.52) dapA [similarity] - Bacillus
subtilis >gi|142830|gb|AAA22385.1| (L08471)
dihydrodipicolinate synthase [Bacillus subtilis]
>gi|2634049|emb|CAB13550.1| (Z99112) dihydrodipicolinate
synthase [Bacillus subtilis]
Length = 290
Score = 110 bits (273), Expect = 2e-23
Identities = 74/271 (27%), Positives = 139/271 (50%), Gaps = 10/271 (3%)
Query: 4 VIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEKGR 63
V ++TPF ++DF+ L I +L + G + V TTGE +L+T+E+ L E
Sbjct: 6 VSTAMITPFDNKGNVDFQKLSTLIDYLLKNGTDSLVVAGTTGESPTLSTEEKIALFEYTV 65
Query: 64 EITSGMY--LVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMVAE 121
+ +G + GTGS +T + I+L++ AE+ G D +++V PYY K E + +HF +A
Sbjct: 66 KEVNGRVPVIAGTGSNNTKDSIKLTKKAEEAGVDAVMLVTPYYNKPSQEGMYQHFKAIAA 125
Query: 122 RVDIPIIVYAIP--SCANPVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEERKD 179
+P+++Y +P + A+ P IR ++ + N++ +K + L + ++I E +D
Sbjct: 126 ETSLPVMLYNVPGRTVASLAPETTIR-LAADIPNVVAIKEASGDLEAITKII--AETPED 182
Query: 180 FRVFTGLDQYFLSTLLLGGDGGIMACANFA-PEIHLQIWNSFKRRNFEEAIKLSRVLGEI 238
F V++G D L L +GG G + ++ A ++ I N + A+ ++L +
Sbjct: 183 FYVYSGDDALTLPILSVGGRGVVSVASHIAGTDMQQMIKNYTNGQTANAALIHQKLLPIM 242
Query: 239 SRIYNVASSFASAVKLAMIAKGFPIKPVLRP 269
++ + + VK A+ +G + V P
Sbjct: 243 KELFKAPN--PAPVKTALQLRGLDVGSVRLP 271
>sp|P40109|DAPA_BRELA DIHYDRODIPICOLINATE SYNTHASE (DHDPS) >gi|423823|pir||C40626
dihydrodipicolinate synthase (EC 4.2.1.52) precursor
[similarity] - Corynebacterium glutamicum
>gi|311770|emb|CAA79714.1| (Z21502) dihydrodipicolinate
synthase [Corynebacterium glutamicum]
Length = 301
Score = 110 bits (272), Expect = 2e-23
Identities = 83/271 (30%), Positives = 130/271 (47%), Gaps = 13/271 (4%)
Query: 6 VPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEKGREI 65
V +VTPF E ID A +L +KG+ + + TTGE + E+ L + RE
Sbjct: 19 VAMVTPFTESGDIDIAAGREVAAYLVDKGLDSLVLAGTTGESPTTTAAEKLELLKAVREE 78
Query: 66 TS--GMYLVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMVAERV 123
+ G G+ +T +EL+ A GADG+++V PYY K E +L HF +A
Sbjct: 79 VGDRAKLIAGVGTNNTRTSVELAEAAASAGADGLLVVTPYYSKPSQEGLLAHFGAIAAAT 138
Query: 124 DIPIIVYAIPSCAN-PVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEERKDFRV 182
++PI +Y IP + P+ D +R++S E I+ VK + L LI +
Sbjct: 139 EVPICLYDIPGRSGIPIESDTMRRLS-ELPTILAVKDAKGDLVAATSLI----KETGLAW 193
Query: 183 FTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEA----IKLSRVLGEI 238
++G D L L LGG G I + AP +++ SF+ + A KLS ++
Sbjct: 194 YSGDDPLNLVWLALGGSGFISVIGHAAPTALRELYTSFEEGDLVRAREINAKLSPLVAAQ 253
Query: 239 SRIYNVASSFASAVKLAMIAKGFPIKPVLRP 269
R+ V+ + A A++L I G P P++ P
Sbjct: 254 GRLGGVSLAKA-ALRLQGINVGDPRLPIMAP 283
>pir||H81878 probable dihydrodipicolinate synthase (EC 4.2.1.52) NMA1124
[imported] - Neisseria meningitidis (group A strain
Z2491) >gi|7379818|emb|CAB84386.1| (AL162755) putative
dihydrodipicolinate synthase [Neisseria meningitidis
Z2491]
Length = 291
Score = 109 bits (271), Expect = 3e-23
Identities = 79/220 (35%), Positives = 114/220 (50%), Gaps = 16/220 (7%)
Query: 1 MEGVIVPLVTPFREDYSIDFEAL----EWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERK 56
++G +V L+TP +D SI +E L +WHI E G GI TTGE +L+ +E
Sbjct: 2 LQGSLVALITPMNQDGSIHYEQLRDLIDWHI----ENGTDGIVAVGTTGESATLSVEEHT 57
Query: 57 MLAEKGREITSGMY--LVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILK 114
+ E + + + GTG+ +T+E I LS+ AE GAD + V PYY K E + +
Sbjct: 58 AVIEAVVKHVAKRVPVIAGTGANNTVEAIALSQAAEKAGADYTLSVVPYYNKPSQEGMYR 117
Query: 115 HFSMVAERVDIPIIVYAIP--SCANPVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIE 172
HF VAE IP+I+Y +P + + I+R E NI+GVK + ++ ELI
Sbjct: 118 HFKAVAEAAAIPMILYNVPGRTVVSMNNETILRLA--EIPNIVGVKEASGNIGSNIELIN 175
Query: 173 VKEERKDFRVFTGLDQYFLSTLLLGGDGGIMACANFAPEI 212
E F V +G D L +L GG G I AN AP++
Sbjct: 176 RAPE--GFVVLSGDDHTALPFMLCGGHGVITVAANAAPKL 213
>sp|P19808|DAPA_CORGL DIHYDRODIPICOLINATE SYNTHASE (DHDPS) >gi|40491|emb|CAA37940.1|
(X53993) L-2,3-dihydrodipicolinate synthetase
[Corynebacterium glutamicum]
Length = 301
Score = 109 bits (269), Expect = 5e-23
Identities = 83/271 (30%), Positives = 129/271 (46%), Gaps = 13/271 (4%)
Query: 6 VPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEKGREI 65
V +VTPF E ID A +L +KG+ + + TTGE + E+ L + RE
Sbjct: 19 VAMVTPFTESGDIDIAAGREVAAYLVDKGLDSLVLAGTTGESPTTTAAEKLELLKAVREE 78
Query: 66 TS--GMYLVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMVAERV 123
+ G G+ +T +EL+ A GADG+++V PYY K E +L HF +A
Sbjct: 79 VGDRAKLIAGVGTNNTRTSVELAEAAASAGADGLLVVTPYYSKPSQEGLLAHFGAIAAAT 138
Query: 124 DIPIIVYAIPSCAN-PVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEERKDFRV 182
++PI +Y IP + P+ D +R++S E I+ VK + L LI +
Sbjct: 139 EVPICLYDIPGRSGIPIESDTMRRLS-ELPTILAVKDAKGDLVAATSLI----KETGLAW 193
Query: 183 FTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEA----IKLSRVLGEI 238
++G D L L LGG G I + AP +++ SF+ + A KLS ++
Sbjct: 194 YSGDDPLNLVWLALGGSGFISVIGHAAPTALRELYTSFEEGDLVRAREINAKLSPLVAAQ 253
Query: 239 SRIYNVASSFASAVKLAMIAKGFPIKPVLRP 269
R+ V+ + A A +L I G P P++ P
Sbjct: 254 GRLGGVSLAKA-ASRLQGINVGDPRLPIMAP 283
>pir||F81352 dihydrodipicolinate synthase (EC 4.2.1.52) Cj0806 [imported] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6968252|emb|CAB73071.1| (AL139076)
dihydrodipicolinate synthase [Campylobacter jejuni]
Length = 298
Score = 109 bits (269), Expect = 5e-23
Identities = 79/289 (27%), Positives = 138/289 (47%), Gaps = 9/289 (3%)
Query: 3 GVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEKG 62
G + L+TPF+ +D ++ I+ E G+ + TTGE +L +E + E
Sbjct: 8 GAMTALITPFKNG-KVDEQSYARLIKRQIENGIDAVVPVGTTGESATLTHEEHRTCIEIA 66
Query: 63 REITSGM---YLVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMV 119
E G L G GS +T E + L++ A++ GADGI+ VAPYY K + + +H+ +
Sbjct: 67 VETCKGTKVKVLAGAGSNATHEAVGLAKFAKEHGADGILSVAPYYNKPTQQGLYEHYKAI 126
Query: 120 AERVDIPIIVYAIPSCAN-PVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEERK 178
A+ VDIP+++Y +P + D I K+ + NI GVK + + + + +++
Sbjct: 127 AQSVDIPVLLYNVPGRTGCEISTDTIIKLFRDCENIYGVKEASGN---IDKCVDLLAHEP 183
Query: 179 DFRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRVLGEI 238
+ +G D L GG G I +N P++ + + N++EA K++ L I
Sbjct: 184 RMMLISGEDAINYPILSNGGKGVISVTSNLLPDMISALTHFALDENYKEAKKINDELYNI 243
Query: 239 SRIYNVASSFASAVKLAMIAKGFPIKPVLRPPHVIDGEEVFNEIKGILR 287
++I S +K AM G R P +E F +I+ +++
Sbjct: 244 NKIL-FCESNPIPIKTAMYLAGLIESLEFRLPLCSPSKENFAKIEEVMK 291
>emb|CAC11758.1| (AL445064) probable 2-keto-3-deoxy gluconate aldolase [Thermoplasma
acidophilum]
Length = 289
Score = 106 bits (262), Expect = 3e-22
Identities = 82/288 (28%), Positives = 145/288 (49%), Gaps = 16/288 (5%)
Query: 5 IVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEKGRE 64
IVP++TPFR + ID E + H L G+ IFV T G +L+ E+KMLAE +
Sbjct: 5 IVPILTPFRGN-EIDGEKFKDHCLKLLRDGIDMIFVAGTNGMGPALSFQEKKMLAEYCSD 63
Query: 65 ITSGMYLVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCK-LKDEEILKHFSMVAERV 123
IT + + GS + E IEL+R A + + + P+Y + +E I+++++ ++E +
Sbjct: 64 ITDRV-IFQVGSLNLEESIELARIARSMNFYAVAALPPFYFGGIPEEWIIRYYTQISEVM 122
Query: 124 DIPIIVYAIPSCAN-PVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEERKDFRV 182
+ +Y P + D+ RK+ + NI+GVK D+++ + ++ K DF V
Sbjct: 123 ET--FIYNYPKFTGYDINADLARKIKKKGGNILGVK---DTVSDIDHMMRYKYLIDDFMV 177
Query: 183 FTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRVLGEISRIY 242
F+G Y L + G DG + A N+A E+ +QI + R I + + SR
Sbjct: 178 FSGPSNYILHAAVNGLDGAVAAAGNYATEMFVQILDDTARYGRANQIIIDEIFDAASRYG 237
Query: 243 NVASSFASAVKLAMIAKGFPIKPVLRPPHVIDG---EEVFNEIKGILR 287
AS+++ L I +G+ P + +D E++ +E++ I++
Sbjct: 238 QWASNYS----LVRILRGYDAGDPRPPFYPLDDHTEEKLRSEVRSIMQ 281
>sp|P43797|DAPA_HAEIN DIHYDRODIPICOLINATE SYNTHASE (DHDPS) >gi|1073997|pir||A64058
dihydrodipicolinate synthase (EC 4.2.1.52) [similarity]
- Haemophilus influenzae (strain Rd KW20)
>gi|1573221|gb|AAC21921.1| (U32711) dihydrodipicolinate
synthetase (dapA) [Haemophilus influenzae Rd]
Length = 298
Score = 102 bits (252), Expect = 5e-21
Identities = 82/290 (28%), Positives = 136/290 (46%), Gaps = 11/290 (3%)
Query: 3 GVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEKG 62
G IV LVTP +DF LE + E G + + TTGE +L+ +E + EK
Sbjct: 10 GSIVALVTPMNHYGEVDFSCLEKLVEHHIEAGSNALVSVGTTGESATLSIEENVKVIEKT 69
Query: 63 REITSGMY--LVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMVA 120
E G + G G+ +T E I +++ D G G + V PYY K E + +HF +A
Sbjct: 70 VEFAKGRIPIIAGAGANATSEAITMTKLLRDSGVAGCLSVVPYYNKPTQEGMYQHFKAIA 129
Query: 121 ERVDIPIIVYAIPS--CANPVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKE-ER 177
E D+P I+Y +PS ++ P + R +E NI+G+K + ++ ++++K+
Sbjct: 130 ECTDLPQILYNVPSRTGSDMKPETVARLAEIE--NIVGIKEATRDVS---RIVKIKQLAG 184
Query: 178 KDFRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRVLGE 237
K+F V +G D L + LG +G I N A + + +F++A +++ L
Sbjct: 185 KNFIVLSGDDATGLEAIKLGAEGVISVTNNIAAKDMADMCRYALAGDFDKAEEINARLMR 244
Query: 238 ISRIYNVASSFASAVKLAMIAKGFPIKPVLRPPHVIDGEEVFNEIKGILR 287
+ + S+ VK A G P LR P EE+ ++ L+
Sbjct: 245 LHHDLFIESN-PIPVKWAAYRLGLIKSPHLRLPLTTLSEEIQPKVGDALK 293
>sp|P05640|DAPA_ECOLI DIHYDRODIPICOLINATE SYNTHASE (DHDPS) >gi|7428345|pir||SYECDP
dihydrodipicolinate synthase (EC 4.2.1.52) [validated] -
Escherichia coli >gi|1942361|pdb|1DHP|A Chain A,
Dihydrodipicolinate Synthase >gi|1942362|pdb|1DHP|B
Chain B, Dihydrodipicolinate Synthase
>gi|1788823|gb|AAC75531.1| (AE000335)
dihydrodipicolinate synthase [Escherichia coli K12]
>gi|1799905|dbj|BAA16355.1| (D90876) dihydrodipicolinate
synthase (EC 4.2.1.52) [Escherichia coli]
>gi|1805536|dbj|BAA16365.1| (D90877) dihydrodipicolinate
synthase (EC 4.2.1.52) [Escherichia coli]
Length = 292
Score = 102 bits (252), Expect = 5e-21
Identities = 74/232 (31%), Positives = 111/232 (46%), Gaps = 12/232 (5%)
Query: 3 GVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEKG 62
G IV +VTP E ++ +L+ I + G I TTGE +LN DE +
Sbjct: 4 GSIVAIVTPMDEKGNVCRASLKKLIDYHVASGTSAIVSVGTTGESATLNHDEHADVVMMT 63
Query: 63 REITSGMY--LVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMVA 120
++ G + GTG+ +T E I L++ D G G + V PYY + E + +HF +A
Sbjct: 64 LDLADGRIPVIAGTGANATAEAISLTQRFNDSGIVGCLTVTPYYNRPSQEGLYQHFKAIA 123
Query: 121 ERVDIPIIVYAIPSCAN----PVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEE 176
E D+P I+Y +PS P V + KV NIIG+K + +LT + ++ E+ +
Sbjct: 124 EHTDLPQILYNVPSRTGCDLLPETVGRLAKV----KNIIGIKEATGNLTRVNQIKELVSD 179
Query: 177 RKDFRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEA 228
DF + +G D L + LGG G I AN A Q+ +F EA
Sbjct: 180 --DFVLLSGDDASALDFMQLGGHGVISVTANVAARDMAQMCKLAAEGHFAEA 229
>gb|AAA23665.1| (M12844) dihydrodipicolinate synthetase (dapA) [Escherichia coli]
Length = 292
Score = 101 bits (250), Expect = 8e-21
Identities = 73/232 (31%), Positives = 110/232 (46%), Gaps = 12/232 (5%)
Query: 3 GVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEKG 62
G IV +VTP E ++ +L+ I + G I TTGE +LN DE +
Sbjct: 4 GSIVAIVTPMDEKGNVCRASLKKLIDYHVASGTSAIVSVGTTGESATLNHDEHADVVMMT 63
Query: 63 REITSGMY--LVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMVA 120
++ G + GTG+ +T E I L++ D G G + V PYY + E + +HF +A
Sbjct: 64 LDLADGRIPVIAGTGANATAEAISLTQRFNDSGIVGCLTVTPYYNRPSQEGLYQHFKAIA 123
Query: 121 ERVDIPIIVYAIPSCAN----PVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEE 176
E D+P I+Y +PS P V + KV NIIG+K + +LT + ++ E+ +
Sbjct: 124 EHTDLPQILYNVPSRTGCDLLPETVGRLAKV----KNIIGIKEATGNLTRVNQIKELVSD 179
Query: 177 RKDFRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEA 228
DF + +G D L + LGG G I N A Q+ +F EA
Sbjct: 180 --DFVLLSGDDASALDFMQLGGHGVISVTTNVAARDMAQMCKLAAEEHFAEA 229
>pir||H82113 dihydrodipicolinate synthase VC2157 [imported] - Vibrio cholerae
(group O1 strain N16961) >gi|9656709|gb|AAF95302.1|
(AE004287) dihydrodipicolinate synthase [Vibrio
cholerae]
Length = 292
Score = 100 bits (246), Expect = 2e-20
Identities = 76/265 (28%), Positives = 129/265 (48%), Gaps = 10/265 (3%)
Query: 3 GVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEKG 62
G IV L+TPF D +D+ +L+ + F + G I TTGE +L +E + K
Sbjct: 4 GSIVALITPFTPDGEVDYISLKKLVDFHVDAGTDAIVSVGTTGESATLTVEEHVKVVAKT 63
Query: 63 REITSGMY--LVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMVA 120
E G + GTG+ +T E + SR + G G + V PYY K E + H++ +A
Sbjct: 64 VEFAEGRLPIIAGTGANATHEAVTFSRLLNNTGIAGYLSVTPYYNKPTQEGLFLHYNAIA 123
Query: 121 ERVDIPIIVYAIPS-CANPVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEERKD 179
+ DIP+I+Y +P A + + + ++S E NI+ +K + L+ + + E+ +E
Sbjct: 124 QETDIPVILYNVPGRTAVDMRPETVARLS-EIKNIVALKDATGDLSRVAKHREMCKE--G 180
Query: 180 FRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRVLGEIS 239
F + +G D L + LGG G I N A ++ + F+EA +++ L +
Sbjct: 181 FVLLSGDDATGLEFVKLGGQGVISVTNNIAAADMAKMMHLALDGKFDEAAIINQRLMTLH 240
Query: 240 RIYNVASSFA----SAVKLAMIAKG 260
+ + SS +A K+ +IA G
Sbjct: 241 KNLFIESSPIPVKWAAHKMGLIANG 265
>sp|P06995|NPL_ECOLI N-ACETYLNEURAMINATE LYASE SUBUNIT (N-ACETYLNEURAMINIC ACID
ALDOLASE) (N-ACETYLNEURAMINATE PYRUVATE LYASE) (NALASE)
>gi|68222|pir||WZECN N-acetylneuraminate lyase (EC
4.1.3.3) - Escherichia coli >gi|216589|dbj|BAA00046.1|
(D00067) N-acetylneuraminate lyase [Escherichia coli]
>gi|606164|gb|AAA58027.1| (U18997) N-acetylneuraminate
lyase [Escherichia coli] >gi|1789620|gb|AAC76257.1|
(AE000402) N-acetylneuraminate lyase (aldolase);
catabolism of sialic acid; not K12? [Escherichia coli
K12] >gi|225112|prf||1209156A lyase,acetylneuraminate
[Escherichia coli]
Length = 297
Score = 98.3 bits (241), Expect = 1e-19
Identities = 74/296 (25%), Positives = 136/296 (45%), Gaps = 15/296 (5%)
Query: 1 MEGVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAE 60
+ GV+ L+TPF + ++D +L ++F ++G+ G++V +TGE + ER+ + E
Sbjct: 5 LRGVMAALLTPFDQQQALDKASLRRLVQFNIQQGIDGLYVGGSTGEAFVQSLSEREQVLE 64
Query: 61 KGREITSG--MYLVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSM 118
E G + G ST E +L+ A+ G D + V P+Y EE H+
Sbjct: 65 IVAEEAKGKIKLIAHVGCVSTAESQQLAASAKRYGFDAVSAVTPFYYPFSFEEHCDHYRA 124
Query: 119 VAERVD-IPIIVYAIPSCANPVPVDIIRKVSLEYSNII----GVKASVDSLTYLQELIEV 173
+ + D +P++VY IP+ + K++L+ N + GV A + L ++ ++
Sbjct: 125 IIDSADGLPMVVYNIPALSGV-------KLTLDQINTLVTLPGVGALKQTSGDLYQMEQI 177
Query: 174 KEERKDFRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSR 233
+ E D ++ G D+ F S LL G DGGI + N + I + K + + A KL
Sbjct: 178 RREHPDLVLYNGYDEIFASGLLAGADGGIGSTYNIMGWRYQGIVKALKEGDIQTAQKLQT 237
Query: 234 VLGEISRIYNVASSFASAVKLAMIAKGFPIKPVLRPPHVIDGEEVFNEIKGILRSL 289
++ + + + +K + P+ R P E+ E+K + + L
Sbjct: 238 ECNKVIDLL-IKTGVFRGLKTVLHYMDVVSVPLCRKPFGPVDEKYLPELKALAQQL 292
>pdb|1FDZ|A Chain A, N-Acetylneuraminate Lyase In Complex With Pyruvate Via
Borohydride Reduction >gi|2624637|pdb|1FDZ|D Chain D,
N-Acetylneuraminate Lyase In Complex With Pyruvate Via
Borohydride Reduction >gi|2624681|pdb|1FDY|A Chain A,
N-Acetylneuraminate Lyase In Complex With
Hydroxypyruvate >gi|2624682|pdb|1FDY|B Chain B,
N-Acetylneuraminate Lyase In Complex With
Hydroxypyruvate >gi|2624683|pdb|1FDY|C Chain C,
N-Acetylneuraminate Lyase In Complex With
Hydroxypyruvate >gi|2624684|pdb|1FDY|D Chain D,
N-Acetylneuraminate Lyase In Complex With
Hydroxypyruvate >gi|2624635|pdb|1FDZ|B Chain B,
N-Acetylneuraminate Lyase In Complex With Pyruvate Via
Borohydride Reduction >gi|2624636|pdb|1FDZ|C Chain C,
N-Acetylneuraminate Lyase In Complex With Pyruvate Via
Borohydride Reduction
Length = 297
Score = 96.3 bits (236), Expect = 4e-19
Identities = 73/296 (24%), Positives = 136/296 (45%), Gaps = 15/296 (5%)
Query: 1 MEGVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAE 60
+ GV+ L+TPF + ++D +L ++F ++G+ G++V +TGE + ER+ + E
Sbjct: 5 LRGVMAALLTPFDQQQALDKASLRRLVQFNIQQGIDGLYVGGSTGEAFVQSLSEREQVLE 64
Query: 61 KGREITSG--MYLVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSM 118
E G + G +T E +L+ A+ G D + V P+Y EE H+
Sbjct: 65 IVAEEGKGKIKLIAHVGCVTTAESQQLAASAKRYGFDAVSAVTPFYYPFSFEEHCDHYRA 124
Query: 119 VAERVD-IPIIVYAIPSCANPVPVDIIRKVSLEYSNII----GVKASVDSLTYLQELIEV 173
+ + D +P++VY IP+ + K++L+ N + GV A + L ++ ++
Sbjct: 125 IIDSADGLPMVVYNIPALSGV-------KLTLDQINTLVTLPGVGALKQTSGDLYQMEQI 177
Query: 174 KEERKDFRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSR 233
+ E D ++ G D+ F S LL G DGGI + N + I + K + + A KL
Sbjct: 178 RREHPDLVLYNGYDEIFASGLLAGADGGIGSTYNIMGWRYQGIVKALKEGDIQTAQKLQT 237
Query: 234 VLGEISRIYNVASSFASAVKLAMIAKGFPIKPVLRPPHVIDGEEVFNEIKGILRSL 289
++ + + + +K + P+ R P E+ E+K + + L
Sbjct: 238 ECNKVIDLL-IKTGVFRGLKTVLHYMDVVSVPLCRKPFGPVDEKYLPELKALAQQL 292
>pir||H72700 N-acetylneuraminate lyase homolog APE1023 [imported] - Aeropyrum
pernix (strain K1) >gi|5104693|dbj|BAA80008.1|
(AP000060) 294aa long hypothetical N-acetylneuraminate
lyase [Aeropyrum pernix]
Length = 294
Score = 96.0 bits (235), Expect = 5e-19
Identities = 76/274 (27%), Positives = 122/274 (43%), Gaps = 21/274 (7%)
Query: 8 LVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERK--MLAEKGREI 65
+VTP R S+D A W L E GV G+FV TTGE+ L+ ER A I
Sbjct: 1 MVTPLRGG-SVDKNAASWLASRLSESGVDGVFVPGTTGEWYLLDPHERAEAFFAVASSAI 59
Query: 66 TSGMYLVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMVAERVD- 124
+ G E L+ A GA ++ V P Y + + + + + + R
Sbjct: 60 AGLRLVAGVSGYRPEESYRLAEEAAGHGAHAVMAVPPIYFRPSTDFLREFYGEIKRRAGG 119
Query: 125 IPIIVYAIPS-CANPVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEERKDFRVF 183
+P +Y P + V+ + + +E + G+KA+V Y+ L VKE +F V
Sbjct: 120 LPTYIYIFPERMGYTLAVEQVESL-VEAGVVDGIKATVTDAAYIAGLAAVKERNPEFEVL 178
Query: 184 TGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFE-------EAIKLSRVLG 236
G + + T L GGDG + A +N AP++ +++ S ++ + E +KLSR+LG
Sbjct: 179 AGGLEMLVHTSLSGGDGVVDAYSNVAPKLAVELAESLEKGSVERVAGLQGRVLKLSRILG 238
Query: 237 EISRIYNVASSFASAVKLAMIAKGFPIKPVLRPP 270
+ S + +K + G PI +R P
Sbjct: 239 K--------RSLPAVLKAVLHVLGAPITGEVRKP 264
>sp|P57197|DAPA_BUCAI DIHYDRODIPICOLINATE SYNTHASE (DHDPS) >gi|10038780|dbj|BAB12815.1|
(AP001118) dihydrodipicolinate synthase [Buchnera sp.
APS]
Length = 294
Score = 96.0 bits (235), Expect = 5e-19
Identities = 68/237 (28%), Positives = 119/237 (49%), Gaps = 6/237 (2%)
Query: 2 EGVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEK 61
+G IV L+TP E I +LE I + I TTGE +L+ +E +
Sbjct: 3 KGSIVALITPMDEKGQICRISLEKLINYHVASKTEAIVSIGTTGESATLSQEEHINIVML 62
Query: 62 GREITSGMY--LVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMV 119
E+ G + GTG+ +T E I L++ E G G + V PYY + E + +HF +
Sbjct: 63 TLELADGRIPVIAGTGANATTEAISLTKRFEKSGVAGCLSVTPYYNRPTQEGLYQHFKAI 122
Query: 120 AERVDIPIIVYAIPSCAN-PVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEERK 178
+E ++P I+Y +PS + + + K+S ++NIIG+K + L+ + ++ E+ +
Sbjct: 123 SENTELPQILYNVPSRTGCDLLPETVAKLS-HFNNIIGIKEATGDLSRIHKIKEL--VKT 179
Query: 179 DFRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRVL 235
+F + +G D L + LGG G I AN A + ++I + + +F A +++ L
Sbjct: 180 NFLLISGDDATALDFMQLGGQGVISVTANIAAKEMMEICSYALKGDFINARSINKRL 236
>sp|Q55513|DAPA_SYNY3 DIHYDRODIPICOLINATE SYNTHASE (DHDPS) >gi|7436671|pir||S76023
dihydrodipicolinate synthase (EC 4.2.1.52) dapA
[similarity] - Synechocystis sp. (strain PCC 6803)
>gi|1001380|dbj|BAA10870.1| (D64006) dihydrodipicolinate
synthase [Synechocystis sp.]
Length = 301
Score = 95.6 bits (234), Expect = 6e-19
Identities = 79/291 (27%), Positives = 133/291 (45%), Gaps = 11/291 (3%)
Query: 4 VIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEKGR 63
V+ +VTPF D +D+ E L G G+ V TTGE +L+ +E L +
Sbjct: 13 VLTAMVTPFNADGGVDYGVAEKLADHLITHGSDGLVVCGTTGESPTLSWEEEHELFRVVK 72
Query: 64 EITS--GMYLVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMVAE 121
+ G + GTGS T E +E ++ A +G DG + V PYY K E +L HF +A
Sbjct: 73 QTVGDRGSVIAGTGSNCTREAMEATQIAAKLGVDGSLQVVPYYNKPPQEGLLAHFQAIAN 132
Query: 122 -RVDIPIIVYAIPSCANP--VPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEERK 178
++P+++Y IP P + R +E NI+ +K + SL Q +
Sbjct: 133 CAPELPLMLYNIPGRTGQSLAPETVYRLAEVE--NIVAIKEATGSLE--QASLIRAHTPD 188
Query: 179 DFRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRVLGEI 238
DF ++ G D L L +GG G + ++ + + F + +A+++ L +
Sbjct: 189 DFAIYAGDDVLTLPLLAVGGAGVVSVASHLVGDRLQAMVQHFAQGATAQALEIHLQLIPL 248
Query: 239 SRIYNVASSFASAVKLAMIAKGFPIKPVLRPPHVIDGEEVFNEIKGILRSL 289
+I A++ VK A+ +G+P+ RPP +++ +LR L
Sbjct: 249 FKILFCATN-PIPVKTALGLQGWPVGS-FRPPLCALSPGHTEQLRDVLRDL 297
>emb|CAA27051.1| (X03345) N-acetylneuraminate lyase (EC 4.1.3.3) (aa 1-297)
[Escherichia coli]
Length = 297
Score = 95.2 bits (233), Expect = 8e-19
Identities = 73/296 (24%), Positives = 136/296 (45%), Gaps = 15/296 (5%)
Query: 1 MEGVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAE 60
+ GV+ L+TPF + ++D +L ++F ++G+ G++V +TGE + ER+ + E
Sbjct: 5 LRGVMAALLTPFDQQQALDKASLRRLVQFNIQQGIDGLYVGGSTGEAFVQSLSEREQVLE 64
Query: 61 KGREITSG--MYLVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSM 118
E G + G +T E +L+ A+ G D + V P+Y EE H+
Sbjct: 65 IVAEEGKGKIKLIAHVGCVTTAESQQLAASAKRYGFDAVSAVTPFYYPFSFEEHCDHYRA 124
Query: 119 VAERVD-IPIIVYAIPSCANPVPVDIIRKVSLEYSNII----GVKASVDSLTYLQELIEV 173
+ + D +P++VY IP+ + K++L+ N + GV A + L ++ ++
Sbjct: 125 IIDSADGLPMVVYNIPALSGV-------KLTLDQINTLVTLPGVGALKQTSGDLYQMEQI 177
Query: 174 KEERKDFRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSR 233
+ E D ++ G D+ F S LL G DGGI + N + I + K + + A KL
Sbjct: 178 RREHPDLVLYNGYDEIFASGLLAGADGGIGSTYNIMGWRYQGIVKALKEGDIQTAQKLQT 237
Query: 234 VLGEISRIYNVASSFASAVKLAMIAKGFPIKPVLRPPHVIDGEEVFNEIKGILRSL 289
++ + + + +K + P+ R P E+ E+K + + L
Sbjct: 238 ECNKVIDLL-IKTGVFRGLKTVLHYMDVVSVPLCRKPFGPVDEKYQPELKALAQQL 292
>pdb|1NAL|1 Chain 1, Mol_id: 1; Molecule: N-Acetylneuraminate Lyase; Chain: 1,
2, 3, 4; Ec: 4.1.3.3 >gi|1127101|pdb|1NAL|2 Chain 2,
Mol_id: 1; Molecule: N-Acetylneuraminate Lyase; Chain:
1, 2, 3, 4; Ec: 4.1.3.3 >gi|1127102|pdb|1NAL|3 Chain 3,
Mol_id: 1; Molecule: N-Acetylneuraminate Lyase; Chain:
1, 2, 3, 4; Ec: 4.1.3.3 >gi|1127103|pdb|1NAL|4 Chain 4,
Mol_id: 1; Molecule: N-Acetylneuraminate Lyase; Chain:
1, 2, 3, 4; Ec: 4.1.3.3
Length = 297
Score = 95.2 bits (233), Expect = 8e-19
Identities = 73/296 (24%), Positives = 136/296 (45%), Gaps = 15/296 (5%)
Query: 1 MEGVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAE 60
+ GV+ L+TPF + ++D +L ++F ++G+ G++V +TGE + ER+ + E
Sbjct: 5 LRGVMAALLTPFDQQQALDKASLRRLVQFNIQQGIDGLYVGGSTGEAFVQSLSEREQVLE 64
Query: 61 KGREITSG--MYLVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSM 118
E G + G +T E +L+ A+ G D + V P+Y EE H+
Sbjct: 65 IVAEEGKGKIKLIAHVGCVTTAESQQLAASAKRYGFDAVSAVTPFYYPFSFEEHCDHYRA 124
Query: 119 VAERVD-IPIIVYAIPSCANPVPVDIIRKVSLEYSNII----GVKASVDSLTYLQELIEV 173
+ + D +P++VY IP+ + K++L+ N + GV A + L ++ ++
Sbjct: 125 IIDSADGLPMVVYNIPALSGV-------KLTLDQINTLVTLPGVGALKQTSGDLYQMEQI 177
Query: 174 KEERKDFRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSR 233
+ E D ++ G D+ F S LL G DGGI + N + I + K + + A KL
Sbjct: 178 RREHPDLVLYNGYDEIFASGLLAGADGGIGSTYNIMGWRYQGIVKALKEGDIQTAQKLQT 237
Query: 234 VLGEISRIYNVASSFASAVKLAMIAKGFPIKPVLRPPHVIDGEEVFNEIKGILRSL 289
++ + + + +K + P+ R P E+ E+K + + L
Sbjct: 238 ECNKVIDLL-IKTGVFRGLKTVLHYMDVVSVPLCRKPFGPVDEKYQPELKALAQQL 292
>emb|CAA73375.1| (Y12876) N-acetylneuraminate lyase [Clostridium perfringens]
Length = 288
Score = 94.8 bits (232), Expect = 1e-18
Identities = 68/242 (28%), Positives = 119/242 (49%), Gaps = 8/242 (3%)
Query: 1 MEGVIVPLVTPFREDYSIDFEALEWHIRF-LEEKGVHGIFVNSTTGEFTSLNTDERKMLA 59
M+G+ L+ F +D +I+ + L IR ++ + G++V +TGE L+TDE+K +
Sbjct: 1 MKGIYSALLVSFDKDGNINEKGLREIIRHNIDVCKIDGLYVGGSTGENFMLSTDEKKRIF 60
Query: 60 EKGREITSGMY--LVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFS 117
E + G + GS + E +EL++ D+G D I V P+Y K EI ++
Sbjct: 61 EIAMDEAKGQVKLIAQVGSVNLKEAVELAKFTTDLGYDAISAVTPFYYKFDFNEIKHYYE 120
Query: 118 MVAERVDIPIIVYAIPSCANPVPVDIIRKVSL-EYSNIIGVKASVDSLTYLQELIEVKEE 176
+ VD +I+Y+IP V + I + L E IIGVK + L+ + ++
Sbjct: 121 TIINSVDNKLIIYSIPFLTG-VNMSIEQFAELFENDKIIGVKFTAADFYLLERM---RKA 176
Query: 177 RKDFRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRVLG 236
D +F G D+ L +LG DG I + N QI+ + ++ + E A+++ V
Sbjct: 177 FPDKLIFAGFDEMMLPATVLGVDGAIGSTFNVNGVRARQIFEAAQKGDIETALEVQHVTN 236
Query: 237 EI 238
++
Sbjct: 237 DL 238
>pir||B83122 conserved hypothetical protein PA4188 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9950398|gb|AAG07575.1|AE004835_4 (AE004835)
conserved hypothetical protein [Pseudomonas aeruginosa]
Length = 303
Score = 94.8 bits (232), Expect = 1e-18
Identities = 79/292 (27%), Positives = 124/292 (42%), Gaps = 11/292 (3%)
Query: 2 EGVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEK 61
EG+ P +TP D SID +A + FL E VHGI + +TGE+ + +ER LA
Sbjct: 4 EGIYTPAITPLSADGSIDTQAFAEVLEFLVESKVHGIVIGGSTGEYYAHTAEERLALAAH 63
Query: 62 GREITSGM--YLVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMV 119
E+ +G +VGTG+ T + + + A IGAD I++ +P Y EI +H V
Sbjct: 64 ASEVIAGRLPLVVGTGAIRTEDSLAYAEAARAIGADAILVGSPPYALPTSREIAEHVLAV 123
Query: 120 AERVDIPIIVYAIPSCANPVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEERKD 179
+PI++Y P+ + NI+ +K S S L L + R
Sbjct: 124 DRAAGLPIMLYNYPARMGVEMDEAFFAAVAGCRNIVAIKESSGSTAQLHRL-ACRHPR-- 180
Query: 180 FRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRVLGEIS 239
+ G D L G + A +NF P HL ++ + N + K R++ +
Sbjct: 181 IALSCGWDDQALEFFAWGARSWVCAGSNFIPGEHLALYQACVVEN--DFAKGRRIMAAMM 238
Query: 240 RIYNVASS--FASAVKLAMIAKGFPIKPVLRPPHVID--GEEVFNEIKGILR 287
+ + S F ++K G V P +D G+ EI L+
Sbjct: 239 PLMDFLESGHFVQSIKHGCELAGLRAGGVRAPLKALDEAGKAALAEIVARLK 290
>gb|AAD28763.1|AF130859_2 (AF130859) sialic acid lyase [Clostridium perfringens]
Length = 288
Score = 94.4 bits (231), Expect = 1e-18
Identities = 68/242 (28%), Positives = 119/242 (49%), Gaps = 8/242 (3%)
Query: 1 MEGVIVPLVTPFREDYSIDFEALEWHIRF-LEEKGVHGIFVNSTTGEFTSLNTDERKMLA 59
M+G+ L+ F +D +I+ + L IR ++ + G++V +TGE L+TDE+K +
Sbjct: 1 MKGIYSALLVSFDKDGNINEKGLREIIRHNIDVCKIDGLYVGGSTGENFMLSTDEKKRIF 60
Query: 60 EKGREITSGMY--LVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFS 117
E + G + GS + E +EL++ D+G D I V P+Y K EI ++
Sbjct: 61 EIAMDEAKGQVKLIAQVGSVNLKEAVELAKFTTDLGYDAISAVTPFYYKFDFNEIKHYYE 120
Query: 118 MVAERVDIPIIVYAIPSCANPVPVDIIRKVSL-EYSNIIGVKASVDSLTYLQELIEVKEE 176
+ VD +I+Y+IP V + I + L E IIGVK + L+ + ++
Sbjct: 121 TIINSVDNKLIIYSIPFLTG-VNMSIEQFAELFENDKIIGVKFTAADFYLLERM---RKA 176
Query: 177 RKDFRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRVLG 236
D +F G D+ L +LG DG I + N QI+ + ++ + E A+++ V
Sbjct: 177 FPDKLIFAGFDEMMLPATVLGVDGAIGSTFNVNGIRARQIFEAAQKGDIETALEVQHVTN 236
Query: 237 EI 238
++
Sbjct: 237 DL 238
>pir||T36926 dihydrodipicolinate synthase (EC 4.2.1.52) SCI7.30 [similarity] -
Streptomyces coelicolor >gi|5420021|emb|CAB46413.1|
(AL096743) putative dihydrodipicolinate synthase
[Streptomyces coelicolor A3(2)]
Length = 317
Score = 94.4 bits (231), Expect = 1e-18
Identities = 70/273 (25%), Positives = 119/273 (42%), Gaps = 9/273 (3%)
Query: 8 LVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEKGREITS 67
+VTPF ++D + + L +G G+ ++ TTGE + E+ L RE
Sbjct: 29 MVTPFTGSGALDLDGAQRLADRLVARGCDGLVLSGTTGESPTTTDAEKAALVTAVREAVG 88
Query: 68 --GMYLVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMVAERVDI 125
+ G G+ T +EL+ AE GADG+++VAPYY + + + HF VA+ +
Sbjct: 89 DRAALVAGVGTADTRHTVELALAAEKAGADGLLVVAPYYSRPPQDALEAHFREVADASGL 148
Query: 126 PIIVYAIPS-CANPVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEERKDFRVFT 184
P+++Y IP + D + +++ + I+ VK L Q+++ R +
Sbjct: 149 PVMLYDIPGRTGTRIEPDTVVRLA-AHPRIVAVKDCAYDLLGTQKVL----SRTGLAYYA 203
Query: 185 GLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRVLGEISRIYNV 244
G D+ L +G G + AN PE+ + ++F + A L R +
Sbjct: 204 GCDEQILPLYAIGAAGYVSTVANVVPELFRAVLDAFDAGDTGRAALLQRRAVPLVESMMA 263
Query: 245 ASSFASAVKLAMI-AKGFPIKPVLRPPHVIDGE 276
A + A++ A G P PV P D E
Sbjct: 264 AGLPGTVTAKALLGALGLPAGPVRAPLRSADRE 296
>gb|AAF00009.1|AF056977_1 (AF056977) hypothetical protein [Penicillium chrysogenum]
Length = 284
Score = 93.2 bits (228), Expect = 3e-18
Identities = 62/227 (27%), Positives = 110/227 (48%), Gaps = 12/227 (5%)
Query: 18 IDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKML-AEKGREITSGMY-----L 71
+D +E H +L GV G+ + GE L+ +ERK + A R + + Y +
Sbjct: 1 VDLATVEKHAAYLARSGVTGLVTQGSNGEAVHLDREERKAITAATRRAVDAAGYSNMPVI 60
Query: 72 VGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCK--LKDEEILKHFSMVAERVDIPIIV 129
G G+ ST E I+ + + GAD ++++ P Y K + E + HF VA+ +P+++
Sbjct: 61 AGCGAASTRETIQFCQDSGAAGADAVLVLPPSYYKSLVSTESMHAHFRAVADASPVPVLI 120
Query: 130 YAIPSCANPVPVDIIRKVSL-EYSNIIGVKASVDSLTYLQELIEVKEERKDFRVFTGLDQ 188
Y P + + + ++L E+ NIIG K + + +L V + DF F G
Sbjct: 121 YNFPGVQSGLDLSSDDILTLAEHPNIIGCKLTCGNTG---KLARVAAAKPDFLTFGGSAD 177
Query: 189 YFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRVL 235
+ L TL++GG G I AN P +++ ++ +EA K+ ++
Sbjct: 178 FTLQTLVVGGAGIIGGVANMIPRSCVRLMELYRAGKVQEAQKVQAIV 224
>sp|O69782|DAPA_RHIME DIHYDRODIPICOLINATE SYNTHASE (DHDPS) >gi|3036901|emb|CAA10957.1|
(AJ222715) DapA [Sinorhizobium meliloti]
Length = 300
Score = 92.1 bits (225), Expect = 7e-18
Identities = 84/294 (28%), Positives = 139/294 (46%), Gaps = 13/294 (4%)
Query: 3 GVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEKG 62
GV +VTPFRE+ S D + + I +GV G+ V +TGE+ S++ ER + E
Sbjct: 9 GVFPAMVTPFRENGSFDEASFKALIELYISEGVKGVVVTGSTGEWYSMSDAERATVWEVA 68
Query: 63 REITSGMYLV--GTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMVA 120
E +SG V GT + T E + L+R A+ +G DG +++ P E++ +F +A
Sbjct: 69 VEASSGRITVIAGTSAVGTREALALTRTAKAVGVDGCMLLPPGGIFAARNEVVNYFHTLA 128
Query: 121 ERVDIPIIVYAIPSCAN-PVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEERKD 179
V +PI+VY P + D++ +++ + I+ K D YL E+ D
Sbjct: 129 -GVGLPIMVYNNPPRTGVNMDADMVAEIA-KSEEIVSFK---DINRYLYAASEIIYRVCD 183
Query: 180 -FRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRVLGEI 238
VFTGL+ Y S L G G + +N + +N+ + A K +++ ++
Sbjct: 184 KLAVFTGLEPYASSVLPRGAVGVVSTISNICAANMVSYYNAVISGDSATAYKTQKLIDQL 243
Query: 239 SRIYNV--ASSFASAVKLAMIAKGFPIKPVLRPPHVIDGEEVFNEIKGILRSLE 290
A +F S VK AM G P +R PH+ E + +++ LR L+
Sbjct: 244 YHFLPTLGAPAFVS-VKAAMKLLGRP-GGEIRLPHLPANEALIGKLREELRRLK 295
>gb|AAB42182.1| (U35878) N-acetylneuraminate lyase [Trichomonas vaginalis]
Length = 318
Score = 89.3 bits (218), Expect = 5e-17
Identities = 62/242 (25%), Positives = 119/242 (48%), Gaps = 8/242 (3%)
Query: 1 MEGVIVPLVTPFREDYSIDFEALEWHIRF-LEEKGVHGIFVNSTTGEFTSLNTDERKMLA 59
++G+ L+ F ED +I+ + L +R+ +++ + G++V +TGE L+T+E+K +
Sbjct: 29 LKGLFSALLVSFNEDGTINEKGLREIVRYNIDKMKIDGLYVGGSTGENFELSTEEKKQIF 88
Query: 60 EKGREITSGMY--LVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFS 117
++ + GS + E IEL ++A ++G + + V P+Y K EI +++
Sbjct: 89 RIAKDEAKDQVALIAQVGSINIHESIELGKYATELGYNCLSAVTPFYYKFTFPEIKNYYN 148
Query: 118 MVAERVDIPIIVYAIPSCAN-PVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEE 176
+ + +IVY+IP+ + D ++ E IIGVK + L+ VK
Sbjct: 149 TIVNATGMNMIVYSIPALTGVSMTADQFGEL-FENPKIIGVKFTAGDFYLLE---RVKRA 204
Query: 177 RKDFRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRVLG 236
D ++ G D+ L LG DG I + N + QI+ K ++EA+++ V
Sbjct: 205 YPDHLIWAGFDEMMLPACSLGIDGAIGSTFNVNAKRARQIFELSKAGKYDEALEVQHVTN 264
Query: 237 EI 238
++
Sbjct: 265 DL 266
>pir||D83488 probable dihydrodipicolinate synthetase PA1254 [imported] -
Pseudomonas aeruginosa (strain PAO1)
>gi|9947186|gb|AAG04643.1|AE004555_3 (AE004555) probable
dihydrodipicolinate synthetase [Pseudomonas aeruginosa]
Length = 305
Score = 89.3 bits (218), Expect = 5e-17
Identities = 64/233 (27%), Positives = 111/233 (47%), Gaps = 8/233 (3%)
Query: 3 GVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEKG 62
GV + T F D+S++ E I L GV G+ V + GE TSL +E+ + E
Sbjct: 9 GVFPAVTTQFNADFSVNLEETHTVISNLVRDGVSGLVVCGSVGENTSLTIEEKMAVTEVA 68
Query: 63 REITSGM--YLVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMVA 120
++ + G + G ++ ++++ E +G DGI+++ K E +HF VA
Sbjct: 69 KDASGGRVPVICGIAEFTSAGAAKVAKAVERVGVDGIMVMPALVYSSKPHETAEHFRSVA 128
Query: 121 ERVDIPIIVYAIPSC-ANPVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEE-RK 178
D+P++VY P N V DI+ ++ + NI+ K DS + I+V+ + +
Sbjct: 129 SGTDLPVMVYNNPPIYRNDVTPDILVSLA-DCENIVCFK---DSSGDTRRFIDVRNQVGE 184
Query: 179 DFRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKL 231
F +F GLD L ++ +G G I +N P+ I+ + F EA+ +
Sbjct: 185 RFILFAGLDDVVLESVAVGAQGWISGMSNVFPKEGETIFRLARAGRFAEAMPI 237
>sp|P49423|DAPA_PROMA DIHYDRODIPICOLINATE SYNTHASE (DHDPS) >gi|1085110|emb|CAA92211.1|
(Z68126) dihydrodipicolinate synthase [Prochlorococcus
marinus]
Length = 302
Score = 87.8 bits (214), Expect = 1e-16
Identities = 56/170 (32%), Positives = 87/170 (50%), Gaps = 3/170 (1%)
Query: 4 VIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEKGR 63
++ +VTPF ++DF R+L ++G G+ V TTGE +L+ +E+ L E R
Sbjct: 15 LLTAMVTPFDTAGAVDFALAARLARYLVDQGSDGLIVCGTTGESPTLSWEEQYQLLETVR 74
Query: 64 EITSGM--YLVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMVAE 121
+G L GTGS ST E I + A + GADG ++V PYY K + HF VA+
Sbjct: 75 NAVNGSAKVLPGTGSNSTSEAIHATAKAAEAGADGALVVVPYYNKPPQAGLESHFRAVAQ 134
Query: 122 RV-DIPIIVYAIPSCANPVPVDIIRKVSLEYSNIIGVKASVDSLTYLQEL 170
D+P+++Y IP I + + SNI+ KA+ + + +L
Sbjct: 135 AAPDLPLMLYNIPGRTGCSISPITVQRLMNCSNIVSFKAASGTTNEVTDL 184
>pir||G83617 probable dihydrodipicolinate synthetase PA0223 [imported] -
Pseudomonas aeruginosa (strain PAO1)
>gi|9946060|gb|AAG03612.1|AE004460_5 (AE004460) probable
dihydrodipicolinate synthetase [Pseudomonas aeruginosa]
Length = 293
Score = 87.0 bits (212), Expect = 2e-16
Identities = 57/231 (24%), Positives = 110/231 (46%), Gaps = 5/231 (2%)
Query: 1 MEGVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAE 60
+ G+I +TPF D +D AL I L + GVH I +TGE L+ E + +
Sbjct: 5 IHGIIGYTITPFAADGGLDLPALGRSIERLIDGGVHAIAPLGSTGEGAYLSDPEWDEVVD 64
Query: 61 KGREITSGMY--LVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSM 118
+ + +V +T + + ++ AE +GA+ ++++ Y KL + E+ +H+
Sbjct: 65 FTLKTVAHRVPTIVSVSDLTTAKTVRRAQFAESLGAEAVMVLPISYWKLNEAEVFQHYRA 124
Query: 119 VAERVDIPIIVYAIPSCAN-PVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEER 177
V E + +P+++Y P + + V++I ++ E N+ VK S + + +L + E R
Sbjct: 125 VGEAIGVPVMLYNNPGTSGIDMSVELILRIVREVDNVTMVKESTGDIQRMHKLRLLGEGR 184
Query: 178 KDFRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEA 228
F + G + L + G G A N P ++ Q++ + + E+A
Sbjct: 185 VPF--YNGCNPLALEAFVAGAKGWCSAAPNLIPTLNGQLYQAVLDGDLEKA 233
>sp|O05969|DAPA_RICPR DIHYDRODIPICOLINATE SYNTHASE (DHDPS) >gi|7436672|pir||D71701
dihydrodipicolinate synthase (EC 4.2.1.52) RP429
[similarity] - Rickettsia prowazekii
>gi|2073504|emb|CAA72449.1| (Y11777) dihydrodipicolinate
synthetase [Rickettsia prowazekii]
>gi|3860986|emb|CAA14886.1| (AJ235271)
DIHYDRODIPICOLINATE SYNTHASE (dapA) [Rickettsia
prowazekii]
Length = 294
Score = 86.6 bits (211), Expect = 3e-16
Identities = 75/291 (25%), Positives = 137/291 (46%), Gaps = 9/291 (3%)
Query: 2 EGVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEK 61
+G+I L+TPF+ D +D ALE + + + + + +TGE SL+ +E K+L +
Sbjct: 6 KGLITALITPFK-DNKLDLYALENILNQQIKHKIDAVLIAGSTGEANSLSFEEYKLLLKT 64
Query: 62 GREITSGMYLV--GTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMV 119
+I + + G S +T IEL+ ++ IG D + P Y K I KHF +
Sbjct: 65 SVDIVNNRMPIISGCSSNNTAYAIELAIESKKIGVDCFMASPPSYVKPTQHGIYKHFEAL 124
Query: 120 AERVDIPIIVYAIPSCANPVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEERK- 178
E ++PI++Y+ P+ + VD + L S + + A D L+ + ++ K
Sbjct: 125 HEACNLPIMLYSAPTRSG---VDFSDETILRLSKLPRILALKDCGVDLERPMRIRAIVKG 181
Query: 179 DFRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRVLGEI 238
DF + TG D+ L+ G G I +N AP++ ++ + + + A+++ + L +
Sbjct: 182 DFNILTGNDEVVLAFHAQGVVGWISVTSNIAPKLCKELLEKWYNNDTQGALEIHQKLLPL 241
Query: 239 SRIYNVASSFASAVKLAMIAKGFPIKPVLRPPHVIDGEEVFNEIKGILRSL 289
+ + S+ VK A G + +R P + +IK I+ SL
Sbjct: 242 YKALFLESN-PIPVKYAAYYLGL-CENEIRLPLTEASDSAKKQIKKIITSL 290
>pir||T35844 dihydrodipicolinate synthase (EC 4.2.1.52) SC9A10.08 [similarity] -
Streptomyces coelicolor >gi|3413827|emb|CAA20295.1|
(AL031260) putative dihydrodipicolinate synthase
[Streptomyces coelicolor A3(2)]
Length = 299
Score = 86.2 bits (210), Expect = 4e-16
Identities = 71/279 (25%), Positives = 129/279 (45%), Gaps = 13/279 (4%)
Query: 4 VIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEKGR 63
V+ +VTPF D ++D + + L + G G+ +N TTGE + + E+ L
Sbjct: 14 VLTAMVTPFTADGALDLDGAQRLAAHLVDAGNDGLIINGTTGESPTTSDAEKADLVRAVV 73
Query: 64 EITSGM--YLVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMVAE 121
E + G G+ +T IEL+R AE +GA G+++V PYY K E + HF+ +A+
Sbjct: 74 EAVGDRAHVVAGVGTNNTQHSIELARAAERVGAHGLLLVTPYYNKPPQEGLYLHFTAIAD 133
Query: 122 RVDIPIIVYAIPSCANPVPVDIIRKVSL-EYSNIIGVKASVDSLTYLQELIEVKEERKDF 180
+P+++Y IP + VP++ V L E+ I+ K + L I R
Sbjct: 134 AAGLPVMLYDIPG-RSGVPINTETLVRLAEHPRIVANKDAKGDLGRASWAI----ARSGL 188
Query: 181 RVFTGLDQYFLSTLLLGGDGGIMACAN-FAPEIHLQIWNSFKRRNFEEAIKL-SRVLGEI 238
++G D L L +G G + + PE+ + ++ + ++A+++ ++L
Sbjct: 189 AWYSGDDMLNLPLLAVGAVGFVSVVGHVVTPELRAMV-DAHVAGDVQKALEIHQKLLPVF 247
Query: 239 SRIYNVASSFASAVKLAMIAKGFPIKPVLRPPHVIDGEE 277
+ ++ K A+ +G P P+ P + EE
Sbjct: 248 TGMFRTQG--VMTTKGALALQGLPAGPLRAPMVGLTPEE 284
>emb|CAA69950.1| (Y08695) putative acylneuraminate lyase [Clostridium tertium]
Length = 226
Score = 85.8 bits (209), Expect = 5e-16
Identities = 59/216 (27%), Positives = 105/216 (48%), Gaps = 5/216 (2%)
Query: 2 EGVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEK 61
+G+I + ++ I E + ++L +KGV G++V ++GE + +ERK+ E
Sbjct: 8 KGIIPAFYACYDDEGKISPERTQMFTQYLIDKGVKGLYVCGSSGECIYQSKEERKITLEN 67
Query: 62 GREITSGMYLV--GTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMV 119
++ G + G +T + EL+ HAE IG D I + P Y L D I ++++ +
Sbjct: 68 VMKVAKGKITIIAHVGCNNTRDSEELAEHAESIGVDAIASIPPIYFHLPDYSIAEYWNDI 127
Query: 120 AERV-DIPIIVYAIPSCANPVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEERK 178
+ + I+Y IP A + K L+ +IGVK S + +Q ++ +
Sbjct: 128 SNAAPNTDFIIYNIPQLAGVGLGINLYKQMLKNPRVIGVKNSSMPVQDIQMFKDISGD-- 185
Query: 179 DFRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHL 214
+ VF G D+ F++ ++G DGGI PE+ L
Sbjct: 186 ESVVFNGPDEQFVAGRIMGADGGIGGTYAVMPELFL 221
>pir||H70879 dihydrodipicolinate synthase (EC 4.2.1.52) Rv2753c [similarity] -
Mycobacterium tuberculosis (strain H37RV)
>gi|2624275|emb|CAA15549.1| (AL008967) dapA
[Mycobacterium tuberculosis]
Length = 300
Score = 85.8 bits (209), Expect = 5e-16
Identities = 79/292 (27%), Positives = 130/292 (44%), Gaps = 14/292 (4%)
Query: 4 VIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEKGR 63
++ +VTPF D S+D L ++G G+ V+ TTGE + E+ L
Sbjct: 15 LLTAMVTPFSGDGSLDTATAARLANHLVDQGCDGLVVSGTTGESPTTTDGEKIELLRAVL 74
Query: 64 EITS--GMYLVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMVAE 121
E + G G+ T I L++ GA G+++V PYY K + HF+ VA+
Sbjct: 75 EAVGDRARVIAGAGTYDTAHSIRLAKACAAEGAHGLLVVTPYYSKPPQRGLQAHFTAVAD 134
Query: 122 RVDIPIIVYAIPS-CANPVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEERKDF 180
++P+++Y IP A P+ D IR ++ + NI+GVK D+ L ++ +
Sbjct: 135 ATELPMLLYDIPGRSAVPIEPDTIRALA-SHPNIVGVK---DAKADLHSGAQIMAD-TGL 189
Query: 181 RVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRVLGEI-- 238
++G D L L +G G I A+ A ++ ++F + A K++ + +
Sbjct: 190 AYYSGDDALNLPWLAMGATGFISVIAHLAAGQLRELLSAFGSGDIATARKINIAVAPLCN 249
Query: 239 --SRIYNVASSFASAVKLAMIAKGFPIKP-VLRPPHVIDGEEVFNEIKGILR 287
SR+ V S A ++L I G P P V P ID +LR
Sbjct: 250 AMSRLGGVTLSKA-GLRLQGIDVGDPRLPQVAATPEQIDALAADMRAASVLR 300
>pir||D82742 dihydroxydipicolinate synthase XF0963 [imported] - Xylella
fastidiosa (strain 9a5c)
>gi|9105891|gb|AAF83773.1|AE003934_15 (AE003934)
dihydroxydipicolinate synthase [Xylella fastidiosa]
Length = 318
Score = 85.8 bits (209), Expect = 5e-16
Identities = 64/221 (28%), Positives = 111/221 (49%), Gaps = 16/221 (7%)
Query: 1 MEGVIVPLVTPFREDYSIDFEALEWHIRFLEEK---GVHGIFVNSTTGEFTSLNTDER-K 56
+ G+I LVTPF D + D +A W IR L+ + GV G+ + +TGE +L E +
Sbjct: 19 LSGIITALVTPFDRDGAFDRDA--W-IRLLDLQLAGGVQGVVIAGSTGEAATLTDAEYDE 75
Query: 57 MLAEKGREITSGM-YLVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKH 115
ML + + L GTG + T + I ++ A D GA ++V P Y + + H
Sbjct: 76 MLCSAVVRVGGRVPVLAGTGLSGTAKTISQTKRAADNGAGYALVVTPPYIRPNQGGLKAH 135
Query: 116 FSMVAERVDIPIIVYAIPSCANPVPVDIIRKVSLE---YSNIIGVKASVDSLTYLQELIE 172
+ VA++ +P+++Y +PS D++ + + + NI+G+K + S +Q L+
Sbjct: 136 YLAVADQGGLPVVLYNVPSRTG---CDLLPETVADLAGHPNIVGIKEACASRERVQALLA 192
Query: 173 VKEERKDFRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIH 213
++ R F VF+G D ++L G DG + +N P +
Sbjct: 193 LR--RPGFTVFSGDDSSAARSMLDGADGLVSVASNVLPSAY 231
>gb|AAG23543.1|AF244594_1 (AF244594) dihydropicolinate synthase [Carboxydothermus
hydrogenoformans]
Length = 130
Score = 85.8 bits (209), Expect = 5e-16
Identities = 44/89 (49%), Positives = 64/89 (71%), Gaps = 2/89 (2%)
Query: 18 IDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEKGREITSGMY--LVGTG 75
+++E + I FL GVHGIFV ++GEF+ LN +ERK A+ + +G LVGTG
Sbjct: 35 LNWEGNKALIDFLINGGVHGIFVLGSSGEFSHLNAEERKEFAKFVVDYVAGRVPVLVGTG 94
Query: 76 STSTLEVIELSRHAEDIGADGIVIVAPYY 104
S++T EV+EL++HA++IGADG+V+V PYY
Sbjct: 95 SSNTKEVVELTKHAKEIGADGVVVVPPYY 123
>pdb|1F6P|A Chain A, Crystal Structure Analysis Of N-Acetylneuraminate Lyase
From Haemophilus Influenzae: Crystal Form Iii
>gi|11513505|pdb|1F6P|B Chain B, Crystal Structure
Analysis Of N-Acetylneuraminate Lyase From Haemophilus
Influenzae: Crystal Form Iii >gi|11513506|pdb|1F6P|C
Chain C, Crystal Structure Analysis Of
N-Acetylneuraminate Lyase From Haemophilus Influenzae:
Crystal Form Iii >gi|11513507|pdb|1F6P|D Chain D,
Crystal Structure Analysis Of N-Acetylneuraminate Lyase
From Haemophilus Influenzae: Crystal Form Iii
>gi|11513510|pdb|1F73|A Chain A, Crystal Structure
Analysis Of N-Acetylneuraminate Lyase From Haemophilus
Influenzae: Crystal Form Iii In Complex With Sialic Acid
Alditol >gi|11513511|pdb|1F73|B Chain B, Crystal
Structure Analysis Of N-Acetylneuraminate Lyase From
Haemophilus Influenzae: Crystal Form Iii In Complex With
Sialic Acid Alditol >gi|11513512|pdb|1F73|C Chain C,
Crystal Structure Analysis Of N-Acetylneuraminate Lyase
From Haemophilus Influenzae: Crystal Form Iii In Complex
With Sialic Acid Alditol >gi|11513513|pdb|1F73|D Chain
D, Crystal Structure Analysis Of N-Acetylneuraminate
Lyase From Haemophilus Influenzae: Crystal Form Iii In
Complex With Sialic Acid Alditol >gi|11513515|pdb|1F74|A
Chain A, Crystal Structure Analysis Of
N-Acetylneuraminate Lyase From Haemophilus Influenzae:
Crystal Form Ii Complexed With 4-Deoxy-Sialic Acid
>gi|11513516|pdb|1F74|C Chain C, Crystal Structure
Analysis Of N-Acetylneuraminate Lyase From Haemophilus
Influenzae: Crystal Form Ii Complexed With
4-Deoxy-Sialic Acid >gi|11513518|pdb|1F7B|A Chain A,
Crystal Structure Analysis Of N-Acetylneuraminate Lyase
From Haemophilus Influenzae: Crystal Form Ii In Complex
With 4-Oxo-Sialic Acid >gi|11513519|pdb|1F7B|C Chain C,
Crystal Structure Analysis Of N-Acetylneuraminate Lyase
From Haemophilus Influenzae: Crystal Form Ii In Complex
With 4-Oxo-Sialic Acid
Length = 293
Score = 82.7 bits (201), Expect = 5e-15
Identities = 63/244 (25%), Positives = 116/244 (46%), Gaps = 12/244 (4%)
Query: 1 MEGVIVPLVTPFREDYSIDFEALEWHIRF-LEEKGVHGIFVNSTTGEFTSLNTDERKMLA 59
++G+ L+ F ED +I+ + L IR +++ V G++V +TGE L+T+E+K +
Sbjct: 4 LKGIFSALLVSFNEDGTINEKGLRQIIRHNIDKMKVDGLYVGGSTGENFMLSTEEKKEIF 63
Query: 60 EKGREITSGMY--LVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFS 117
++ + GS + E +EL ++A ++G D + V P+Y K EI ++
Sbjct: 64 RIAKDEAKDQIALIAQVGSVNLKEAVELGKYATELGYDCLSAVTPFYYKFSFPEIKHYYD 123
Query: 118 MVAERVDIPIIVYAIPSCANPVPVDI-IRKVSLEYSN--IIGVKASVDSLTYLQELIEVK 174
+ +IVY+IP V++ I + Y N ++GVK + L+ L K
Sbjct: 124 TIIAETGSNMIVYSIPFLTG---VNMGIEQFGELYKNPKVLGVKFTAGDFYLLERL---K 177
Query: 175 EERKDFRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRV 234
+ + ++ G D+ L LG DG I + N QI+ K +EA+++ V
Sbjct: 178 KAYPNHLIWAGFDEMMLPAASLGVDGAIGSTFNVNGVRARQIFELTKAGKLKEALEIQHV 237
Query: 235 LGEI 238
++
Sbjct: 238 TNDL 241
>sp|P44539|NPL_HAEIN PROBABLE N-ACETYLNEURAMINATE LYASE SUBUNIT (N-ACETYLNEURAMINIC ACID
ALDOLASE) (N-ACETYLNEURAMINATE PYRUVATE LYASE) (NALASE)
>gi|1075051|pir||G64050 N-acetylneuraminate lyase (EC
4.1.3.3) [similarity] - Haemophilus influenzae (strain
Rd KW20) >gi|1573098|gb|AAC21814.1| (U32700)
N-acetylneuraminate lyase (nanA) [Haemophilus influenzae
Rd]
Length = 293
Score = 81.5 bits (198), Expect = 1e-14
Identities = 63/244 (25%), Positives = 115/244 (46%), Gaps = 12/244 (4%)
Query: 1 MEGVIVPLVTPFREDYSIDFEALEWHIRF-LEEKGVHGIFVNSTTGEFTSLNTDERKMLA 59
++G+ L+ F ED +I+ + L IR +++ V G++V +TGE L+T+E+K +
Sbjct: 4 LKGIFSALLVSFNEDGTINEKGLRQIIRHNIDKMKVDGLYVGGSTGENFMLSTEEKKEIF 63
Query: 60 EKGREITSGMY--LVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFS 117
++ + GS + E +EL ++A ++G D + V P+Y K EI ++
Sbjct: 64 RIAKDEAKDQIALIAQVGSVNLKEAVELGKYATELGYDCLSAVTPFYYKFSFPEIKHYYD 123
Query: 118 MVAERVDIPIIVYAIPSCANPVPVDI-IRKVSLEYSN--IIGVKASVDSLTYLQELIEVK 174
+ +IVY+IP V++ I + Y N ++GVK + L+ L K
Sbjct: 124 TIIAETGNNMIVYSIPFLTG---VNMGIEQFGELYKNPKVLGVKFTAGDFYLLERL---K 177
Query: 175 EERKDFRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRV 234
+ + ++ G D+ L LG DG I + N QI+ K EA+++ V
Sbjct: 178 KAYPNHLIWAGFDEMMLPAASLGVDGAIGSTFNVNGVRARQIFELTKAGKLAEALEIQHV 237
Query: 235 LGEI 238
++
Sbjct: 238 TNDL 241
>pir||E82157 probable N-acetylneuraminate lyase VC1776 [imported] - Vibrio
cholerae (group O1 strain N16961)
>gi|9656300|gb|AAF94925.1| (AE004255)
N-acetylneuraminate lyase, putative [Vibrio cholerae]
Length = 298
Score = 81.1 bits (197), Expect = 1e-14
Identities = 69/275 (25%), Positives = 128/275 (46%), Gaps = 12/275 (4%)
Query: 1 MEGVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAE 60
+ G+I TPF +D ++F A++ L E+GV G +V TTGE + +ERK +AE
Sbjct: 4 LTGLIAAPHTPFTKDNKVNFAAIDQIAELLIEQGVKGAYVCGTTGEGIHCSVEERKAIAE 63
Query: 61 KGREITSGM--YLVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKD-EEILKHFS 117
+ + G ++ TG+ S ++ I L+ HAE + + P + K ++++++ +
Sbjct: 64 RWVKAVDGKLDVILHTGALSIVDTINLTEHAETLDIFATSAIGPCFFKPGSVDDLVEYCA 123
Query: 118 MVAERVDIPIIVYAIPSCANPVPVDI---IRKVSLEYSNIIGVKASVDSLTYLQELIEVK 174
VA Y S + V +D+ + K N+ G K + L Q + V
Sbjct: 124 QVAAAAPSKGFYY-YHSGMSGVNLDLEQFLIKGEQRIPNLYGAKFNNADLYEYQRCVRVS 182
Query: 175 EERKDFRVFTGLDQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRV 234
+ F + G+D++ + L +G G + + N+A ++L+I +F +E L
Sbjct: 183 NRK--FDIPFGVDEFLPAGLAVGAVGAVGSTYNYAAPLYLKIIEAFNHGKHDEVAALMDK 240
Query: 235 LGEISRI---YNVASSFASAVKLAMIAKGFPIKPV 266
+ I R+ Y ++ A++L I G P P+
Sbjct: 241 VIAIIRVLVEYGGVAAGKVAMQLHGIDAGDPRLPI 275
>sp|P42235|KDGD_BACSU PROBABLE 5-DEHYDRO-4-DEOXYGLUCARATE DEHYDRATASE
(5-KETO-4-DEOXY-GLUCARATE DEHYDRATASE) (KDGDH)
>gi|7428346|pir||F69752 5-dehydro-4-deoxyglucarate
dehydratase homolog ycbC - Bacillus subtilis
>gi|709997|dbj|BAA06467.1| (D30808) homologue of
5-keto-4-deoxyglucarate dehydrogenase [Bacillus
subtilis] >gi|2632532|emb|CAB12040.1| (Z99105) similar
to 5-dehydro-4-deoxyglucarate dehydratase [Bacillus
subtilis]
Length = 308
Score = 80.0 bits (194), Expect = 3e-14
Identities = 71/289 (24%), Positives = 135/289 (46%), Gaps = 7/289 (2%)
Query: 3 GVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEKG 62
G++ V PF +++ EAL +I FL +G+ IF+ +GEF SL+ E + + E
Sbjct: 10 GILGFPVAPFNTQGTLEEEALFQNIEFLLNEGLEAIFIACGSGEFQSLSQKEYEQMVEVA 69
Query: 63 REITSGMYLVGTGSTSTLE-VIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMVAE 121
G V TG L ++ ++ +E GADG +I+ PY + E + ++ + E
Sbjct: 70 VSAAGGKVPVYTGVGGNLSTALDWAQLSEKKGADGYLILPPYLVHGEQEGLYQYAKTIIE 129
Query: 122 RVDIPIIVYAIPSCANPVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEERKDFR 181
D+ I+Y + + V+ I++++ E ++GVK V ++ L+ +R +
Sbjct: 130 STDLNAILYQRDNAV--LSVEQIKRLT-ECEQLVGVKDGVGNMDLNINLVYTIGDRLGWL 186
Query: 182 VFTGLDQYFLSTLL-LGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSR-VLGEIS 239
+ + + L +G A +N+ P I +++ K N E +L R V+ I+
Sbjct: 187 NGMPMAEVTMPAYLPIGFHSYSSAISNYIPHISRMFYDALKNGNDELVKELYRHVILPIN 246
Query: 240 RIYNVASSFA-SAVKLAMIAKGFPIKPVLRPPHVIDGEEVFNEIKGILR 287
I +A S +K M G ++ RPP ++ + +++ IL+
Sbjct: 247 DIRKQRKGYAVSLIKAGMEIMGLNVRNTARPPVGPVEKDHYQQLEAILK 295
>dbj|BAA77934.1| (D83536) Hypothetical protein F319 [Escherichia coli]
Length = 128
Score = 77.6 bits (188), Expect = 2e-13
Identities = 43/113 (38%), Positives = 63/113 (55%), Gaps = 2/113 (1%)
Query: 3 GVIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEKG 62
G+I P+ T F D +D I L + GV G+F + GEF+ L +ERK +A
Sbjct: 16 GIIPPVSTIFTADGQLDKPGTAALIDDLIKAGVDGLFFLGSGGEFSQLGAEERKAIARFA 75
Query: 63 REITSGMY--LVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEIL 113
+ L+GTG T+ E IELS+HA + GADGIV++ PYY K+ + ++
Sbjct: 76 IDHVDRRVPVLIGTGGTNARETIELSQHAHEAGADGIVVINPYYWKVSEANLI 128
>sp|P26259|DAPA_MAIZE DIHYDRODIPICOLINATE SYNTHASE PRECURSOR (DHDPS)
Length = 380
Score = 71.8 bits (173), Expect = 9e-12
Identities = 53/163 (32%), Positives = 79/163 (47%), Gaps = 10/163 (6%)
Query: 4 VIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEKGR 63
+I + TP+ D D EA + I E G G+ V TTGE ++ DE ML G
Sbjct: 83 LITAVKTPYLPDGRFDLEAYDSLINMQIEGGAEGVIVGGTTGEGHLMSWDEHIMLI--GH 140
Query: 64 EIT---SGMYLVG-TGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMV 119
+ S + ++G TGS ST E + + +G + + PYY K E ++ HF V
Sbjct: 141 TVNCFGSRIKVIGNTGSNSTREAVHATEQGFAVGMHAALHINPYYGKTSAEGMISHFEAV 200
Query: 120 AERVDIPIIVYAIPS-CANPVPVDIIRKVSLEYSNIIGVKASV 161
P I+Y +PS A +P ++I +S Y+N+ GVK V
Sbjct: 201 LPMG--PTIIYNVPSRSAQDIPPEVILAIS-GYTNMAGVKECV 240
>prf||1718320A dihydrodipicolinate synthase [Zea mays]
Length = 380
Score = 71.8 bits (173), Expect = 9e-12
Identities = 53/163 (32%), Positives = 79/163 (47%), Gaps = 10/163 (6%)
Query: 4 VIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEKGR 63
+I + TP+ D D EA + I E G G+ V TTGE ++ DE ML G
Sbjct: 83 LITAVKTPYLPDGRFDLEAYDSLINMQIEGGAEGVIVGGTTGEGHLMSWDEHIMLI--GH 140
Query: 64 EIT---SGMYLVG-TGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMV 119
+ S + ++G TGS ST E + + +G + + PYY K E ++ HF V
Sbjct: 141 TVNCFGSRIKVIGNTGSNSTREAVHATEQGFAVGMHAALHINPYYGKTSAEGMISHFEAV 200
Query: 120 AERVDIPIIVYAIPS-CANPVPVDIIRKVSLEYSNIIGVKASV 161
P I+Y +PS A +P ++I +S Y+N+ GVK V
Sbjct: 201 LPMG--PTIIYNVPSRSAQDIPPEVILAIS-GYTNMAGVKECV 240
>prf||2208495A dihydrodipicolinate synthase [Zea mays]
Length = 368
Score = 71.8 bits (173), Expect = 9e-12
Identities = 53/163 (32%), Positives = 79/163 (47%), Gaps = 10/163 (6%)
Query: 4 VIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEKGR 63
+I + TP+ D D EA + I E G G+ V TTGE ++ DE ML G
Sbjct: 83 LITAVKTPYLPDGRFDLEAYDSLINMQIEGGAEGVIVGGTTGEGHLMSWDEHIMLI--GH 140
Query: 64 EIT---SGMYLVG-TGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMV 119
+ S + ++G TGS ST E + + +G + + PYY K E ++ HF V
Sbjct: 141 TVNCFGSRIKVIGNTGSNSTREAVHATEQGFAVGMHAALHINPYYGKTSAEGMISHFEAV 200
Query: 120 AERVDIPIIVYAIPS-CANPVPVDIIRKVSLEYSNIIGVKASV 161
P I+Y +PS A +P ++I +S Y+N+ GVK V
Sbjct: 201 LPMG--PTIIYNVPSRSAQDIPPEVILAIS-GYTNMAGVKECV 240
>pir||WZZMP dihydrodipicolinate synthase (EC 4.2.1.52) precursor [validated] -
maize >gi|1638871|emb|CAA37038.1| (X52850)
dihydrodipicolinate [Zea mays]
Length = 380
Score = 71.8 bits (173), Expect = 9e-12
Identities = 53/163 (32%), Positives = 79/163 (47%), Gaps = 10/163 (6%)
Query: 4 VIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEKGR 63
+I + TP+ D D EA + I E G G+ V TTGE ++ DE ML G
Sbjct: 83 LITAVKTPYLPDGRFDLEAYDSLINMQIEGGAEGVIVGGTTGEGHLMSWDEHIMLI--GH 140
Query: 64 EIT---SGMYLVG-TGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMV 119
+ S + ++G TGS ST E + + +G + + PYY K E ++ HF V
Sbjct: 141 TVNCFGSRIKVIGNTGSNSTREAVHATEQGFAVGMHAALHINPYYGKTSAEGMISHFEAV 200
Query: 120 AERVDIPIIVYAIPS-CANPVPVDIIRKVSLEYSNIIGVKASV 161
P I+Y +PS A +P ++I +S Y+N+ GVK V
Sbjct: 201 LPMG--PTIIYNVPSRSAQDIPPEVILAIS-GYTNMAGVKECV 240
>sp|Q39535|DAPA_COILA DIHYDRODIPICOLINATE SYNTHASE PRECURSOR (DHDPS)
>gi|1432156|gb|AAB04021.1| (U61730) dihydrodipicolinate
synthase [Coix lacryma-jobi]
Length = 377
Score = 71.4 bits (172), Expect = 1e-11
Identities = 75/276 (27%), Positives = 121/276 (43%), Gaps = 27/276 (9%)
Query: 4 VIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEKGR 63
+I + TP+ D D EA + I E G G+ V TTGE ++ DE ML G
Sbjct: 80 LITAVKTPYLPDGRFDLEAYDSLINMQIEGGAEGVIVGGTTGEGHLMSWDEHIMLI--GH 137
Query: 64 EIT---SGMYLVG-TGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMV 119
+ S + ++G TGS ST E + + +G + + PYY K E ++ HF V
Sbjct: 138 TVNCFGSRIKVIGNTGSNSTREAVHATEQGFAVGMHAALHINPYYGKTSTEGMISHFESV 197
Query: 120 AERVDIPIIVYAIPS-CANPVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEERK 178
P I+Y +PS A +P ++I +S Y N+ GVK + E I+ + K
Sbjct: 198 LPMG--PTIIYNVPSRSAQDIPPEVIVAIS-GYINMAGVKECIG-----HERIKHYAD-K 248
Query: 179 DFRVFTGL-DQYFLSTLLLGGDGGIMACANFAPEI-HLQIWNSFKRRNFEEAIKLSRVLG 236
+++G D+ S G G I +N P + H ++ E A+ ++L
Sbjct: 249 GITIWSGNDDECHDSRWKYGATGVISVTSNLVPGLMHSLMYKG------ENAVLKEKLLP 302
Query: 237 EISRIYNVASSFASAVKLAMIAKGFPIKPVLRPPHV 272
+ ++ + A LA + +PV R P+V
Sbjct: 303 LMKWLFCQPNPIALNTALAQLGVA---RPVFRLPYV 335
>pir||T36909 probable dihydropicolinate synthase - Streptomyces coelicolor
>gi|5420004|emb|CAB46396.1| (AL096743) putative
dihydropicolinate synthase [Streptomyces coelicolor
A3(2)]
Length = 316
Score = 71.4 bits (172), Expect = 1e-11
Identities = 62/212 (29%), Positives = 97/212 (45%), Gaps = 12/212 (5%)
Query: 9 VTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEKGREITSG 68
VT + D +D + H+R E G +F TGEF +L +E E ++G
Sbjct: 21 VTAYGPDGGLDLDVYRTHVRRGVEAGAAAVFACCGTGEFHALTPEEFAACVRAAVEESAG 80
Query: 69 MY--LVGTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMVAERVDIP 126
L G G + L V +R AE GADG++ + PY E +++H+ VA +P
Sbjct: 81 RVPVLAGAGYGTALAV-RYARLAEQAGADGLLAMPPYLVLAGQEGLVRHYREVAAATPLP 139
Query: 127 IIVYAIPSCANPVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIE-VKEE--RKDFRVF 183
+IVY + A P ++ + ++G+K + L +Q ++ V+ E ++F F
Sbjct: 140 VIVYQRDN-AVFTPESVVELARTD--GVVGLKDGLGDLDLMQRIVSAVRTELPGEEFLYF 196
Query: 184 TGL---DQYFLSTLLLGGDGGIMACANFAPEI 212
GL +Q LS LG A FAPEI
Sbjct: 197 NGLPTAEQTQLSYRALGVPLYSSAVFCFAPEI 228
>gb|AAF44718.1|L77616_1 (L77616) dihydrodipicolinate synthase [Oryza sativa]
Length = 347
Score = 70.2 bits (169), Expect = 3e-11
Identities = 55/163 (33%), Positives = 77/163 (46%), Gaps = 10/163 (6%)
Query: 4 VIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEKGR 63
VI + TP+ D D EA + I E G G+ V TTGE ++ DE ML G
Sbjct: 50 VITAVKTPYLPDGRFDLEAYDSLINMQIEGGAEGVIVGGTTGEGHLMSWDEHIMLI--GH 107
Query: 64 EIT---SGMYLVG-TGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMV 119
+ + + +VG TGS ST E I + +G + + PYY K E ++ HF V
Sbjct: 108 TVNCFGTKIKVVGNTGSNSTREAIHATEQGFAVGMHAALHINPYYGKTSVEGLISHFEAV 167
Query: 120 AERVDIPIIVYAIPSCA-NPVPVDIIRKVSLEYSNIIGVKASV 161
P I+Y +PS +P +I VS Y+N+ GVK V
Sbjct: 168 LPMG--PTIIYNVPSRDWQDIPPPVIEAVS-SYTNMAGVKECV 207
>sp|P24846|DAP1_WHEAT DIHYDRODIPICOLINATE SYNTHASE 1 PRECURSOR (DHDPS)
>gi|68224|pir||WZWTH7 dihydrodipicolinate synthase (EC
4.2.1.52) precursor (clone pDA17) [similarity] - wheat
>gi|170680|gb|AAA34263.1| (M60598) dihydrodipicolinate
synthase [Triticum aestivum]
Length = 388
Score = 69.1 bits (166), Expect = 6e-11
Identities = 52/163 (31%), Positives = 77/163 (46%), Gaps = 10/163 (6%)
Query: 4 VIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEKGR 63
+I + TP+ D D EA + I G G+ V TTGE ++ DE ML G
Sbjct: 91 LITAVKTPYLPDGRFDLEAYDSLINTQINGGAEGVIVGGTTGEGHLMSWDEHIMLI--GH 148
Query: 64 EIT---SGMYLVG-TGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMV 119
+ + + ++G TGS ST E + + +G + V PYY K E ++ HF V
Sbjct: 149 TVNCFGANIKVIGNTGSNSTREAVHATEQGFAVGMHAALHVNPYYGKTSTEGLISHFKEV 208
Query: 120 AERVDIPIIVYAIPS-CANPVPVDIIRKVSLEYSNIIGVKASV 161
P I+Y +PS + +P +I +S YSN+ GVK V
Sbjct: 209 LPMG--PTIIYNVPSRTSQDIPPPVIEALS-SYSNMAGVKECV 248
>pir||T47899 dihydrodipicolinate synthase precursor - Arabidopsis thaliana
>gi|7329698|emb|CAB82692.1| (AL162295)
dihydrodipicolinate synthase precursor [Arabidopsis
thaliana]
Length = 364
Score = 69.1 bits (166), Expect = 6e-11
Identities = 76/273 (27%), Positives = 115/273 (41%), Gaps = 21/273 (7%)
Query: 4 VIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEKGR 63
VI + TP+ D D +A + + E G G+ V TTGE ++ DE ML
Sbjct: 67 VITAIKTPYLPDGRFDLQAYDDLVNTQIENGAEGVIVGGTTGEGQLMSWDEHIMLIGHTV 126
Query: 64 EITSGMYLV--GTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMVAE 121
G V TGS ST E I + +G G + + PYY K E + HF V
Sbjct: 127 NCFGGRIKVIGNTGSNSTREAIHATEQGFAMGMHGALHINPYYGKTSIEGMNAHFQTVLH 186
Query: 122 RVDIPIIVYAIPS-CANPVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEERKDF 180
P I+Y +P +P +I K+S + N+ GVK V + ++E E K
Sbjct: 187 MG--PTIIYNVPGRTCQDIPPQVIFKLS-QNPNMAGVKECVGN-NRVEEYTE-----KGI 237
Query: 181 RVFTGL-DQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRVLGEIS 239
V++G DQ S G G I +N P + ++ F+ RN KL ++ +
Sbjct: 238 VVWSGNDDQCHDSRWDHGATGVISVTSNLVPGLMRKL--MFEGRNSALNAKLLPLMDWLF 295
Query: 240 RIYNVASSFASAVKLAMIAKGFPIKPVLRPPHV 272
+ N + +L + +PV R P+V
Sbjct: 296 QEPNPIGVNTALAQLGV------ARPVFRLPYV 322
>sp|Q42948|DAPA_TOBAC DIHYDRODIPICOLINATE SYNTHASE PRECURSOR (DHDPS)
>gi|7436660|pir||T03214 dihydrodipicolinate synthase (EC
4.2.1.52) precursor, chloroplast [validated] - common
tobacco >gi|1213069|emb|CAA56123.1| (X79675)
dihydrodipicolinate synthase [Nicotiana tabacum]
Length = 359
Score = 68.7 bits (165), Expect = 8e-11
Identities = 70/274 (25%), Positives = 116/274 (41%), Gaps = 23/274 (8%)
Query: 4 VIVPLVTPFREDYSIDFEALEWHIRFLEEKGVHGIFVNSTTGEFTSLNTDERKMLAEKGR 63
+I + TP+ D D EA + + E G G+ V TTGE ++ DE ML
Sbjct: 62 LITAIKTPYLPDGRFDLEAYDTLVNLQIENGAEGVIVGGTTGEGQLMSWDEHIMLIGHTV 121
Query: 64 EITSGMYLV--GTGSTSTLEVIELSRHAEDIGADGIVIVAPYYCKLKDEEILKHFSMVAE 121
G V TGS ST E I + +G + + PYY K E ++ HF V
Sbjct: 122 NCFGGSIKVIGNTGSNSTREAIHATEQGFAVGMHAALHINPYYGKTSLEGLISHFESVLP 181
Query: 122 RVDIPIIVYAIPS-CANPVPVDIIRKVSLEYSNIIGVKASVDSLTYLQELIEVKEERKD- 179
P I+Y +PS +P +I+ ++ + N+ GVK V + V++ D
Sbjct: 182 MG--PTIIYNVPSRTGQDIPPRVIQTMA-KSPNLAGVKECVGN-------DRVEQYTSDG 231
Query: 180 FRVFTGL-DQYFLSTLLLGGDGGIMACANFAPEIHLQIWNSFKRRNFEEAIKLSRVLGEI 238
V++G D+ +S G G I +N P + ++ K S+++ +
Sbjct: 232 VVVWSGNDDECHVSRWDYGATGVISVTSNLVPGLMRELMFGGKNPALN-----SKLMPLM 286
Query: 239 SRIYNVASSFASAVKLAMIAKGFPIKPVLRPPHV 272
+++ + A LA + ++PV R P+V
Sbjct: 287 EWLFHEPNPIALNTALAQLG---VVRPVFRLPYV 317
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.321 0.140 0.399
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 108164257
Number of Sequences: 2977
Number of extensions: 4481484
Number of successful extensions: 9823
Number of sequences better than 1.0e-10: 74
Number of HSP's better than 0.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 64
Number of HSP's that attempted gapping in prelim test: 9681
Number of HSP's gapped (non-prelim): 74
length of query: 294
length of database: 189,106,746
effective HSP length: 56
effective length of query: 238
effective length of database: 155,591,474
effective search space: 37030770812
effective search space used: 37030770812
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 165 (68.7 bits)