BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB0848 (moxR-3) DE:methanol dehydrogenase regulatory protein
(moxR-3)
         (314 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||C75037 methanol dehydrogenase regulatory protein (moxr-3) P...   612  e-174
pir||B71126 hypothetical protein PH0776 - Pyrococcus horikoshii ...   567  e-161
pir||F71139 hypothetical protein PH0329 - Pyrococcus horikoshii ...   359  3e-98
pir||B75012 methanol dehydrogenase regulatory protein (moxr-1) P...   354  5e-97
gi|11500001 methanol dehydrogenase regulatory protein (moxR) [Ar...   350  1e-95
pir||B70947 probable moxR3 protein - Mycobacterium tuberculosis ...   344  8e-94
pir||T35917 probable regulatory protein - Streptomyces coelicolo...   337  1e-91
dbj|BAB04323.1| (AP001509) methanol dehydrogenase regulatory pro...   337  1e-91
pir||G71146 hypothetical protein PH0385 - Pyrococcus horikoshii ...   334  9e-91
pir||D75008 methanol dehydrogenase regulatory protein (moxr-2) P...   328  7e-89
gb|AAG18829.1| (AE004987) methanol dehydrogenase regulatory prot...   324  8e-88
pir||C69791 methanol dehydrogenase regulation homolog yeaC - Bac...   322  4e-87
pir||H72289 hypothetical protein TM1132 - Thermotoga maritima (s...   309  2e-83
pir||D72767 hypothetical protein APE0127 - Aeropyrum pernix (str...   307  1e-82
dbj|BAB04450.1| (AP001509) unknown conserved protein [Bacillus h...   305  6e-82
pir||D75460 MoxR-related protein - Deinococcus radiodurans (stra...   300  1e-80
pir||E70792 probable regulatory protein - Mycobacterium tubercul...   300  2e-80
pir||H70321 conserved hypothetical protein aq_240 - Aquifex aeol...   300  2e-80
pir||T34964 probable regulatory protein - Streptomyces coelicolo...   298  4e-80
emb|CAB90929.1| (AL355774) putative regulatory protein [Streptom...   298  5e-80
pir||F72606 probable methanol dehydrogenase regulator APE1317 - ...   295  5e-79
emb|CAC12049.1| (AL445065) regulatory protein moxR related prote...   287  1e-76
pir||B70874 probable moxR protein - Mycobacterium tuberculosis (...   286  3e-76
pir||C83106 conserved hypothetical protein PA4322 [imported] - P...   284  7e-76
pir||S75782 methanol dehydrogenase regulatory protein - Synechoc...   283  2e-75
pir||S74593 MorR protein - Synechocystis sp. (strain PCC 6803) >...   283  2e-75
pir||H70121 methanol dehydrogenase regulator (moxR) homolog - Ly...   282  3e-75
pir||G82635 methanol dehydrogenase regulatory protein XF1813 [im...   281  8e-75
pir||G83261 conserved hypothetical protein PA3070 [imported] - P...   277  2e-73
emb|CAB98184.1| (AJ276161) putative regulatory protein [Streptom...   275  4e-73
pir||H83287 conserved hypothetical protein PA2875 [imported] - P...   274  8e-73
emb|CAA65298.1| (X96434) moxR [Borrelia burgdorferi] >gi|2689172...   273  2e-72
pir||B75496 moxR protein - Deinococcus radiodurans (strain R1) >...   271  7e-72
pir||H82493 MoxR-related protein VCA0175 [imported] - Vibrio cho...   263  3e-69
gb|AAC46196.1| (AF002133) transcriptional regulator [Mycobacteri...   214  9e-55
pir||S43189 hypothetical protein - Pseudomonas aeruginosa >gi|46...   209  3e-53
gb|AAB91544.1| (AF017119) MoxR homolog [Allochromatium vinosum]       196  3e-49
gb|AAB62561.1| (AF006054) MoxR [Mycobacterium tuberculosis]           193  2e-48
dbj|BAA23276.1| (AB004097) ORF4 [Hyphomicrobium methylovorum]         146  3e-34
sp|P30621|MOXR_METEX MOXR PROTEIN (MXAR PROTEIN) >gi|1771259|emb...   143  3e-33
sp|P29901|MOXR_PARDE MOXR PROTEIN >gi|94691|pir||D41377 methanol...   127  1e-28
pir||E69109 conserved hypothetical protein MTH1814 - Methanobact...    74  2e-12
pir||C65178 hypothetical 57.4 kD protein in asnA-kup intergenic ...    69  6e-11
sp|P31473|YIEN_ECOLI HYPOTHETICAL 56.4 KD PROTEIN IN ASNA-KUP IN...    69  6e-11

>pir||C75037 methanol dehydrogenase regulatory protein (moxr-3) PAB0848 -
           Pyrococcus abyssi (strain Orsay)
           >gi|5458705|emb|CAB50192.1| (AJ248287) methanol
           dehydrogenase regulatory protein (moxR-3) [Pyrococcus
           abyssi]
           Length = 314
           
 Score =  612 bits (1562), Expect = e-174
 Identities = 314/314 (100%), Positives = 314/314 (100%)

Query: 1   MNVQVKAQKVLEEVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALG 60
           MNVQVKAQKVLEEVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALG
Sbjct: 1   MNVQVKAQKVLEEVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALG 60

Query: 61  LEFRRVQFTPDLLPSDILGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLE 120
           LEFRRVQFTPDLLPSDILGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLE
Sbjct: 61  LEFRRVQFTPDLLPSDILGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLE 120

Query: 121 AMQERQVTIEGNTYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPSKEEEK 180
           AMQERQVTIEGNTYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPSKEEEK
Sbjct: 121 AMQERQVTIEGNTYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPSKEEEK 180

Query: 181 EILKRRIERKMDDVEINTVLSPEDILRMQREIEEVYVSDAIIEYITSLVWATREDKREIE 240
           EILKRRIERKMDDVEINTVLSPEDILRMQREIEEVYVSDAIIEYITSLVWATREDKREIE
Sbjct: 181 EILKRRIERKMDDVEINTVLSPEDILRMQREIEEVYVSDAIIEYITSLVWATREDKREIE 240

Query: 241 VGVSPRGSLALLKLSRAYAAIEGRDYVIPDDVKAVAVPALSHRIILKRELWYMRIRQEDI 300
           VGVSPRGSLALLKLSRAYAAIEGRDYVIPDDVKAVAVPALSHRIILKRELWYMRIRQEDI
Sbjct: 241 VGVSPRGSLALLKLSRAYAAIEGRDYVIPDDVKAVAVPALSHRIILKRELWYMRIRQEDI 300

Query: 301 IKKILEKVPVPKFE 314
           IKKILEKVPVPKFE
Sbjct: 301 IKKILEKVPVPKFE 314


>pir||B71126 hypothetical protein PH0776 - Pyrococcus horikoshii
           >gi|3257185|dbj|BAA29868.1| (AP000003) 314aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 314
           
 Score =  567 bits (1445), Expect = e-161
 Identities = 282/314 (89%), Positives = 306/314 (96%)

Query: 1   MNVQVKAQKVLEEVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALG 60
           M+VQ KAQ V+EEVKKAIVGKDNVLKL+LA++LADGHILIEDLPGLAKTLMAKSFAKALG
Sbjct: 1   MDVQKKAQMVIEEVKKAIVGKDNVLKLVLATILADGHILIEDLPGLAKTLMAKSFAKALG 60

Query: 61  LEFRRVQFTPDLLPSDILGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLE 120
           LEF+RVQFTPDLLPSDILGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLE
Sbjct: 61  LEFKRVQFTPDLLPSDILGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLE 120

Query: 121 AMQERQVTIEGNTYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPSKEEEK 180
           AMQERQVTIEG TY+LP+PFIVIATQNPIEQEGTYPLPEAQLDRFLVRLR+GYPSK+EEK
Sbjct: 121 AMQERQVTIEGVTYKLPKPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRMGYPSKDEEK 180

Query: 181 EILKRRIERKMDDVEINTVLSPEDILRMQREIEEVYVSDAIIEYITSLVWATREDKREIE 240
           EIL+RRIERK D+VEI TVLSP+D+L+MQRE+E+VYVSDAIIEYITSLVWATREDKR+IE
Sbjct: 181 EILRRRIERKQDEVEIETVLSPKDVLKMQREVEDVYVSDAIIEYITSLVWATREDKRDIE 240

Query: 241 VGVSPRGSLALLKLSRAYAAIEGRDYVIPDDVKAVAVPALSHRIILKRELWYMRIRQEDI 300
           +GVSPRGSLALLKLSRAYAAIEGRDYVIPDDVKAVA+PALSHRIILKRELWY R+ QE +
Sbjct: 241 IGVSPRGSLALLKLSRAYAAIEGRDYVIPDDVKAVAIPALSHRIILKRELWYTRVSQESV 300

Query: 301 IKKILEKVPVPKFE 314
           I+KILE+VPVPKFE
Sbjct: 301 IEKILERVPVPKFE 314


>pir||F71139 hypothetical protein PH0329 - Pyrococcus horikoshii
           >gi|3256720|dbj|BAA29403.1| (AP000002) 317aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 317
           
 Score =  359 bits (911), Expect = 3e-98
 Identities = 187/311 (60%), Positives = 239/311 (76%), Gaps = 5/311 (1%)

Query: 6   KAQKVLEEVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALGLEFRR 65
           + +K++E +    +G ++V++ +LA  L +G+IL ED PGL KTL+AK+FAK LGL+F+R
Sbjct: 4   EVKKIIEAIGDIFIGHEDVIRKVLAVALVNGNILFEDYPGLGKTLLAKAFAKILGLKFKR 63

Query: 66  VQFTPDLLPSDILGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLEAMQER 125
           +QFTPDLLP+DI+G  V+  +   FE  KGP+FTNILLADEINRAPPKTQSALLEAM+ER
Sbjct: 64  IQFTPDLLPADIIGTKVWKPEKGAFEVVKGPIFTNILLADEINRAPPKTQSALLEAMEER 123

Query: 126 QVTIEGNTYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYP-SKEEEKEILK 184
           QVTIEG T++L RPF +IATQNP+E EGTYPLPEAQLDRFLVRL +GYP ++E+E EILK
Sbjct: 124 QVTIEGETFKLERPFFIIATQNPLELEGTYPLPEAQLDRFLVRLNIGYPRNEEDELEILK 183

Query: 185 RRIERKMDD--VEINTVLSPEDILRMQREIEE-VYVSDAIIEYITSLVWATREDKREIEV 241
            R+    DD   +I+ ++S ED +RMQ E+E  V + D I+ YI  LV   RED+R IE 
Sbjct: 184 ARLRWGKDDPTSDISPIISREDFIRMQEEVERGVIIHDDILRYIVRLVRRIREDER-IEA 242

Query: 242 GVSPRGSLALLKLSRAYAAIEGRDYVIPDDVKAVAVPALSHRIILKRELWYMRIRQEDII 301
           G SPRG LAL+KL++A A IEGR YVIPDDVK  AV AL+HRI+LK E    R   E+II
Sbjct: 243 GPSPRGGLALMKLAKANAFIEGRSYVIPDDVKYFAVEALAHRIVLKPEYSLERGIAEEII 302

Query: 302 KKILEKVPVPK 312
           +++LE+VPVPK
Sbjct: 303 REVLEEVPVPK 313


>pir||B75012 methanol dehydrogenase regulatory protein (moxr-1) PAB1276 -
           Pyrococcus abyssi (strain Orsay)
           >gi|5459050|emb|CAB50536.1| (AJ248288) methanol
           dehydrogenase regulatory protein (moxR-1) [Pyrococcus
           abyssi]
           Length = 317
           
 Score =  354 bits (900), Expect = 5e-97
 Identities = 184/311 (59%), Positives = 237/311 (76%), Gaps = 5/311 (1%)

Query: 6   KAQKVLEEVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALGLEFRR 65
           + ++V+  + +  +GK  V++ + A+ L +G++L ED PGL KTL+AK+FAK LGL +RR
Sbjct: 4   RIEEVINSIGEVFIGKVEVVRKVFAAALVNGNVLFEDHPGLGKTLLAKAFAKVLGLNYRR 63

Query: 66  VQFTPDLLPSDILGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLEAMQER 125
           +QFTPDLLP+DI+G  V+  +   FE  KGP+FTN+LLADEINRAPPKTQSALLEAM+ER
Sbjct: 64  IQFTPDLLPADIIGTKVWRPEKGVFEIMKGPIFTNVLLADEINRAPPKTQSALLEAMEER 123

Query: 126 QVTIEGNTYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYP-SKEEEKEILK 184
           QVTIEG T++L +PF VIATQNP+E EGTYPLPEAQLDRFLVRL VGYP S++EE EILK
Sbjct: 124 QVTIEGETFRLEQPFFVIATQNPLEFEGTYPLPEAQLDRFLVRLSVGYPGSEDEEMEILK 183

Query: 185 RRIERKMDD--VEINTVLSPEDILRMQREIE-EVYVSDAIIEYITSLVWATREDKREIEV 241
            R+    DD  V++  VLS E+ L MQR +E EV V D I+ YI  +V   RED+R +E 
Sbjct: 184 ARLRWGKDDPTVDLKPVLSKEEFLEMQRRVEHEVKVHDDILRYIVRIVRRIREDER-VEA 242

Query: 242 GVSPRGSLALLKLSRAYAAIEGRDYVIPDDVKAVAVPALSHRIILKRELWYMRIRQEDII 301
           G SPRG+LAL+KLS+A A IEGRD+VIPDDVKA  + ALSHRI+LK E    R  + +I+
Sbjct: 243 GPSPRGALALMKLSKANAFIEGRDFVIPDDVKAFVIDALSHRIVLKPEYSLERGLEREIV 302

Query: 302 KKILEKVPVPK 312
           ++ + +VPVPK
Sbjct: 303 EEAVNEVPVPK 313


>gi|11500001 methanol dehydrogenase regulatory protein (moxR) [Archaeoglobus
           fulgidus] >gi|7428883|pir||B69553 methanol dehydrogenase
           regulatory protein (moxR) homolog - Archaeoglobus
           fulgidus >gi|2650675|gb|AAB91247.1| (AE001108) methanol
           dehydrogenase regulatory protein (moxR) [Archaeoglobus
           fulgidus]
           Length = 324
           
 Score =  350 bits (889), Expect = 1e-95
 Identities = 179/309 (57%), Positives = 238/309 (76%), Gaps = 6/309 (1%)

Query: 9   KVLEEVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALGLEFRRVQF 68
           ++++ V    VG  N+++ MLA+ L +G+IL ED PGL KTL+AK FA+ +G ++RRVQF
Sbjct: 15  RIVKAVCDVYVGDKNLVEKMLAAALTNGNILFEDYPGLGKTLLAKVFARVIGADYRRVQF 74

Query: 69  TPDLLPSDILGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLEAMQERQVT 128
           TPDLLPSDI+GV ++      FEF KGP+FTN+LLADEINR+PPKTQ+ALLEAM+E+Q+T
Sbjct: 75  TPDLLPSDIIGVKIWRGD--RFEFVKGPIFTNVLLADEINRSPPKTQAALLEAMEEKQIT 132

Query: 129 IEGNTYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYP-SKEEEKEILKRRI 187
           +EG T+ L  PF V+ATQNPIEQEGTYPLPEAQ+DRF++R+R GYP S EEE EIL+RRI
Sbjct: 133 VEGETFSLSMPFFVLATQNPIEQEGTYPLPEAQMDRFMLRMRPGYPESIEEEMEILRRRI 192

Query: 188 ERKMDD--VEINTVLSPEDILRMQREIEEVYVSDAIIEYITSLVWATREDKREIEVGVSP 245
             + DD   ++  V+S E   R+Q  +E VYV  +I++YI+ LV ATRE +  +E+G SP
Sbjct: 193 SWRKDDPTEDVEPVVSLETFRRIQDAVEAVYVDKSILKYISELVRATREHEL-VELGSSP 251

Query: 246 RGSLALLKLSRAYAAIEGRDYVIPDDVKAVAVPALSHRIILKRELWYMRIRQEDIIKKIL 305
           RG LALLKL+RA A ++GRD+VIPDDVK VAV AL+HR+ILK E     +R E+++++IL
Sbjct: 252 RGGLALLKLARALAVMDGRDFVIPDDVKRVAVEALAHRVILKFEYAVEGLRAEEVVEEIL 311

Query: 306 EKVPVPKFE 314
             V VPK+E
Sbjct: 312 NSVRVPKYE 320


>pir||B70947 probable moxR3 protein - Mycobacterium tuberculosis (strain H37RV)
           >gi|2827574|emb|CAA16629.1| (AL021646) moxR3
           [Mycobacterium tuberculosis]
           Length = 320
           
 Score =  344 bits (873), Expect = 8e-94
 Identities = 165/305 (54%), Positives = 231/305 (75%), Gaps = 1/305 (0%)

Query: 8   QKVLEEVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALGLEFRRVQ 67
           + VL+E+++ +VGK + L L+L ++LA GH+LIEDLPGL KTL+A+SFA ALGL+F RVQ
Sbjct: 13  EAVLDEIERVVVGKRSALTLILTAVLARGHVLIEDLPGLGKTLIARSFAAALGLDFTRVQ 72

Query: 68  FTPDLLPSDILGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLEAMQERQV 127
           FTPDLLP+D+LG  +++ ++  FEF+ GP+FTN+LLADEINR PPKTQ+ALLEAM E QV
Sbjct: 73  FTPDLLPADLLGSTIYDMQSGRFEFRAGPIFTNLLLADEINRTPPKTQAALLEAMAEGQV 132

Query: 128 TIEGNTYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPSKEEEKEILKRRI 187
           +I+G T++L  PFIV+AT NPIE EGTYPLPEAQLDRF +RL + Y S+ +E  +L+RR+
Sbjct: 133 SIDGQTHKLAMPFIVLATDNPIEYEGTYPLPEAQLDRFAIRLELRYLSERDETSMLRRRL 192

Query: 188 ERKMDDVEINTVLSPEDILRMQREIEEVYVSDAIIEYITSLVWATREDKREIEVGVSPRG 247
           ER   D  +N V+   D+L M+  +E+V V + ++ Y+ SL  ATR    ++ VG SPR 
Sbjct: 193 ERGSADPTVNQVVDCHDLLAMRESVEQVTVHEDVLHYVVSLANATRHHP-QVAVGASPRA 251

Query: 248 SLALLKLSRAYAAIEGRDYVIPDDVKAVAVPALSHRIILKRELWYMRIRQEDIIKKILEK 307
            L L++LSRA A + GRDYVIP+DVK +A  A++HRI L+ E+W  +I   D++ ++L +
Sbjct: 252 ELDLVQLSRARALLLGRDYVIPEDVKELATAAVAHRITLRPEMWVRKIAGADVVSELLRR 311

Query: 308 VPVPK 312
           +PVP+
Sbjct: 312 LPVPR 316


>pir||T35917 probable regulatory protein - Streptomyces coelicolor
           >gi|4160330|emb|CAA22801.1| (AL035212) putative
           regulatory protein [Streptomyces coelicolor A3(2)]
           Length = 332
           
 Score =  337 bits (855), Expect = 1e-91
 Identities = 160/306 (52%), Positives = 229/306 (74%), Gaps = 1/306 (0%)

Query: 6   KAQKVLEEVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALGLEFRR 65
           +A  VL E+ +A+VGK + L+ ++ ++LA GH+L+EDLPGL KTL+A+SFA  LGL+FRR
Sbjct: 18  QAGAVLREIGRAVVGKPDALEHVMLAVLAGGHVLVEDLPGLGKTLLARSFATTLGLDFRR 77

Query: 66  VQFTPDLLPSDILGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLEAMQER 125
           +QFTPDLLPSD+ G  +++Q++ E  F  GPVFT++LLADEINR PPKTQ+ALLEAM E 
Sbjct: 78  IQFTPDLLPSDVTGTPLYDQRSGEMVFHPGPVFTHLLLADEINRTPPKTQAALLEAMAES 137

Query: 126 QVTIEGNTYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPSKEEEKEILKR 185
           QVT++G T  L  PF+VIAT NP+E EGTY LPEAQLDRF +R+R+GY +  EE  +L+ 
Sbjct: 138 QVTVDGETRPLADPFLVIATANPVEYEGTYSLPEAQLDRFQLRVRMGYLAAREELAMLRA 197

Query: 186 RIERKMDDVEINTVLSPEDILRMQREIEEVYVSDAIIEYITSLVWATREDKREIEVGVSP 245
           RI+R   +  +  +  P+D++  +  +E V + D ++EY  +LV ATR D  +I +G SP
Sbjct: 198 RIDRAAPEAVLERLAGPDDVVAWRAVVERVEIDDDLLEYAVALVGATR-DHPQISIGASP 256

Query: 246 RGSLALLKLSRAYAAIEGRDYVIPDDVKAVAVPALSHRIILKRELWYMRIRQEDIIKKIL 305
           RG LAL++L+RA A ++GRDYV+P+DVK +AVPAL+HR+ L+ ELW   +  +D++++I+
Sbjct: 257 RGGLALVQLARARAVLDGRDYVVPEDVKGLAVPALAHRVSLRPELWVREMSTDDVLREIV 316

Query: 306 EKVPVP 311
           + V  P
Sbjct: 317 DSVGTP 322


>dbj|BAB04323.1| (AP001509) methanol dehydrogenase regulatory protein [Bacillus
           halodurans]
           Length = 318
           
 Score =  337 bits (854), Expect = 1e-91
 Identities = 158/303 (52%), Positives = 232/303 (76%), Gaps = 2/303 (0%)

Query: 9   KVLEEVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALGLEFRRVQF 68
           +V+E V++ +VGK   ++L L ++ A GH+L+ED+PG+ KT++ K+ A++LG +F+R+QF
Sbjct: 10  RVIENVERVVVGKRQEIELSLVALFASGHVLLEDVPGVGKTMLVKAIARSLGADFKRIQF 69

Query: 69  TPDLLPSDILGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLEAMQERQVT 128
           TPDLLPSD+ GV+++NQKT +FEF+ GP+  N++LADEINR  PKTQSALLEA++E  VT
Sbjct: 70  TPDLLPSDVTGVSIYNQKTQQFEFRPGPIMANVVLADEINRTSPKTQSALLEALEEGSVT 129

Query: 129 IEGNTYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPSKEEEKEILKRRIE 188
           IEG +  L +PF V+ATQNP+E  GTYPLPEAQLDRFL RL++GYP  +EE ++LK R+E
Sbjct: 130 IEGKSLVLSKPFFVMATQNPVEYAGTYPLPEAQLDRFLFRLQLGYPKPDEELDVLK-RLE 188

Query: 189 RKMDDVEINTVLSPEDILRMQREIEEVYVSDAIIEYITSLVWATREDKREIEVGVSPRGS 248
           +K    E++ V+  E+++++Q EI++V+V D +  YI  +V  TR+ ++ +E+GVSPRGS
Sbjct: 189 KKHPIQELSPVMETEEVIQLQEEIKDVFVEDNVKAYIVEIVNLTRKHQK-VELGVSPRGS 247

Query: 249 LALLKLSRAYAAIEGRDYVIPDDVKAVAVPALSHRIILKRELWYMRIRQEDIIKKILEKV 308
           +A++K ++AYA I+GRDYVIPDD+K +A  ALSHR+IL  E        E+II  +L++ 
Sbjct: 248 IAMMKAAQAYAMIQGRDYVIPDDIKTLAPFALSHRLILTAEAKMSGTDHEEIIHDVLQQA 307

Query: 309 PVP 311
            VP
Sbjct: 308 KVP 310


>pir||G71146 hypothetical protein PH0385 - Pyrococcus horikoshii
           >gi|3256777|dbj|BAA29460.1| (AP000002) 312aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 312
           
 Score =  334 bits (847), Expect = 9e-91
 Identities = 166/300 (55%), Positives = 232/300 (77%), Gaps = 3/300 (1%)

Query: 12  EEVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALGLEFRRVQFTPD 71
           EEV KA+VGKD+V++L+  ++LA+GH++IE +PG+AKT +AKSFA+ LGL+F R+Q TPD
Sbjct: 15  EEVHKAVVGKDDVIELLAIALLAEGHVMIEGVPGVAKTTIAKSFAQVLGLKFSRIQLTPD 74

Query: 72  LLPSDILGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLEAMQERQVTIEG 131
           LLP+DILG   ++Q    ++ KKGP+F N++LADEINRA PKTQSALLEAMQERQVTIEG
Sbjct: 75  LLPADILGTVYYDQSDGLWKIKKGPIFANVVLADEINRAQPKTQSALLEAMQERQVTIEG 134

Query: 132 NTYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPSKEEEKEILKRRIERKM 191
            T+ L +PF+VIAT+NPIE EG Y LPEAQ+DRF++ +++GYP++EEE E+L+++   ++
Sbjct: 135 RTFPLEKPFMVIATKNPIEFEGVYNLPEAQVDRFMLNIKIGYPTREEEVEMLRKKDRGEL 194

Query: 192 DDVEINTVLSPEDILRMQREIEEVYVSDAIIEYITSLVWATREDKREIEVGVSPRGSLAL 251
              E+  + S E I+RM  E++ V  S+ ++ Y+  +V  TR+D+R I VG SPR S  L
Sbjct: 195 G--EVGRIFSREQIVRMINEVKRVKTSEEVLHYLYEIVNETRKDERLI-VGASPRASEHL 251

Query: 252 LKLSRAYAAIEGRDYVIPDDVKAVAVPALSHRIILKRELWYMRIRQEDIIKKILEKVPVP 311
           L  S+A A +EGRDYVIPDDVK +AVP L+HR+++K E     I+ EDI+++ILE+V VP
Sbjct: 252 LYASKAKAFLEGRDYVIPDDVKFLAVPVLAHRLLIKAEHEIEGIKGEDIVREILERVEVP 311


>pir||D75008 methanol dehydrogenase regulatory protein (moxr-2) PAB1296 -
           Pyrococcus abyssi (strain Orsay)
           >gi|5459020|emb|CAB50506.1| (AJ248288) methanol
           dehydrogenase regulatory protein (moxR-2) [Pyrococcus
           abyssi]
           Length = 309
           
 Score =  328 bits (831), Expect = 7e-89
 Identities = 162/300 (54%), Positives = 228/300 (76%), Gaps = 3/300 (1%)

Query: 12  EEVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALGLEFRRVQFTPD 71
           +E+ KA+VGKD+V++L+  ++L++GH++IE +PG+AKT +AK+FA+ALGL+F R+Q TPD
Sbjct: 12  KEIHKAVVGKDDVIELLAIALLSEGHVIIEGIPGVAKTTIAKNFAQALGLKFSRIQLTPD 71

Query: 72  LLPSDILGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLEAMQERQVTIEG 131
           L P+DI+G   ++Q    ++ KKGP+F N++LADEINRA PKTQSALLEAMQERQVTIEG
Sbjct: 72  LFPADIIGTVYYDQLDGNWKIKKGPIFANVILADEINRAQPKTQSALLEAMQERQVTIEG 131

Query: 132 NTYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPSKEEEKEILKRRIERKM 191
            TY+L RPF++IAT+NP+E EG Y LPEAQLDRF+++++VGYPSKEEE E+LKR+ +   
Sbjct: 132 RTYKLERPFLLIATKNPLEFEGVYNLPEAQLDRFMLQIKVGYPSKEEELEMLKRKDKGLF 191

Query: 192 DDVEINTVLSPEDILRMQREIEEVYVSDAIIEYITSLVWATREDKREIEVGVSPRGSLAL 251
              E   V S + I++M      V +SD ++EY+  ++  TR DKR + VG SPR +  L
Sbjct: 192 S--EAKRVFSRDQIIKMIELARRVRISDEVLEYLYEIINLTRVDKR-LLVGASPRAAEHL 248

Query: 252 LKLSRAYAAIEGRDYVIPDDVKAVAVPALSHRIILKRELWYMRIRQEDIIKKILEKVPVP 311
           L  S+A A +EGRDYVIPDD+K++AVP L+HR+++K E     I  E ++++IL KV VP
Sbjct: 249 LYASKAKAFLEGRDYVIPDDIKSLAVPVLAHRLLVKAEYEVEGITGERVVREILNKVEVP 308


>gb|AAG18829.1| (AE004987) methanol dehydrogenase regulatory protein; MoxR
           [Halobacterium sp. NRC-1]
           Length = 318
           
 Score =  324 bits (822), Expect = 8e-88
 Identities = 159/302 (52%), Positives = 217/302 (71%), Gaps = 1/302 (0%)

Query: 10  VLEEVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALGLEFRRVQFT 69
           V++EV  A++     L+ +L   LADGH+L+ED+PG  KTL A+S A ALGLEF RVQFT
Sbjct: 13  VVDEVAAAVIADREFLETVLVGFLADGHVLLEDVPGTGKTLTARSVATALGLEFSRVQFT 72

Query: 70  PDLLPSDILGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLEAMQERQVTI 129
           PDLLP+D+LG +VFN+++ EFEF+ GPVF N++LADEINRAPPKTQ+ALLEAM+E QVTI
Sbjct: 73  PDLLPTDVLGTHVFNERSREFEFRPGPVFANVVLADEINRAPPKTQAALLEAMEEGQVTI 132

Query: 130 EGNTYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPSKEEEKEILKRRIER 189
           +G T  LP PF VIATQNP++QEGT+PLPEAQLDRF+V   +GYP    E+E+L RR  R
Sbjct: 133 DGETMALPEPFFVIATQNPVDQEGTFPLPEAQLDRFVVSAAIGYPDAAGERELLARRASR 192

Query: 190 KMDDVEINTVLSPEDILRMQREIEEVYVSDAIIEYITSLVWATREDKREIEVGVSPRGSL 249
                 ++ VL  E +  ++R  E+V V   + EY+ ++  ATRE  R +EVGVSPRG+ 
Sbjct: 193 DARSPTVDAVLDDERVRALRRASEDVRVGSDLREYMVAVARATREHPR-VEVGVSPRGTQ 251

Query: 250 ALLKLSRAYAAIEGRDYVIPDDVKAVAVPALSHRIILKRELWYMRIRQEDIIKKILEKVP 309
            L + +RA A + GR+YV+P DVK +A   L+HR++L  +     + +  I++ +L++VP
Sbjct: 252 RLFEAARARAVVAGREYVVPADVKGLAGSVLAHRLVLTPDAAVENVAKGGIVEGVLDEVP 311

Query: 310 VP 311
           VP
Sbjct: 312 VP 313


>pir||C69791 methanol dehydrogenase regulation homolog yeaC - Bacillus subtilis
           >gi|1708641|gb|AAB62308.1| (U51115) YeaC [Bacillus
           subtilis] >gi|2632946|emb|CAB12452.1| (Z99107) similar
           to methanol dehydrogenase regulation [Bacillus subtilis]
           Length = 320
           
 Score =  322 bits (816), Expect = 4e-87
 Identities = 155/301 (51%), Positives = 225/301 (74%), Gaps = 4/301 (1%)

Query: 12  EEVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALGLEFRRVQFTPD 71
           E + + +VGK ++  L LA++LA GH+L+ED+PG+ KT+M ++ AK++G +F+R+QFTPD
Sbjct: 16  EHINRVMVGKRDIAILSLAALLAKGHVLLEDVPGVGKTMMVRALAKSIGADFKRIQFTPD 75

Query: 72  LLPSDILGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLEAMQERQVTIEG 131
           LLPSD+ GV+++N KT+EFE++ GP+  NI+LADEINR  PKTQSALLEAM+E  VT++G
Sbjct: 76  LLPSDVTGVSIYNAKTMEFEYRPGPIMGNIVLADEINRTSPKTQSALLEAMEEGSVTVDG 135

Query: 132 NTYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPSKEEEKEILKRRIERKM 191
           +T QL  PF V+ATQNP+E EGTYPLPEAQLDRFL +LR+GYPS  EE ++L   ++ K 
Sbjct: 136 HTMQLADPFFVMATQNPVEYEGTYPLPEAQLDRFLFKLRMGYPSFNEELDVLS--LQEKS 193

Query: 192 DDVE-INTVLSPEDILRMQREIEEVYVSDAIIEYITSLVWATREDKREIEVGVSPRGSLA 250
             +E +  V++ ED + +QRE++ V   D+I EYI  +V  TR+    +++GVSPRGS+A
Sbjct: 194 HPIETLEPVIAKEDFIFLQREVQNVRADDSIKEYIVEIVQKTRQHP-SVQLGVSPRGSIA 252

Query: 251 LLKLSRAYAAIEGRDYVIPDDVKAVAVPALSHRIILKRELWYMRIRQEDIIKKILEKVPV 310
           L+K ++AYA +  RDYVIPDD++ +A   L HR++L  E  +  I+ E I+++I+  V V
Sbjct: 253 LMKAAQAYALLHHRDYVIPDDIQYLAPFTLPHRMMLHPEAKFEGIQAEAIVREIMSAVKV 312

Query: 311 P 311
           P
Sbjct: 313 P 313


>pir||H72289 hypothetical protein TM1132 - Thermotoga maritima (strain MSB8)
           >gi|4981679|gb|AAD36208.1|AE001771_1 (AE001771) moxR
           protein, putative [Thermotoga maritima]
           Length = 305
           
 Score =  309 bits (784), Expect = 2e-83
 Identities = 147/305 (48%), Positives = 231/305 (75%), Gaps = 2/305 (0%)

Query: 8   QKVLEEVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALGLEFRRVQ 67
           ++V+  ++K I GK   +++++A++LA GH+L+ED+PG+ KT++A++ A +LG++FRRVQ
Sbjct: 3   ERVINNIEKVIKGKREAIEVVVAALLAKGHVLMEDVPGVGKTMLARALALSLGVDFRRVQ 62

Query: 68  FTPDLLPSDILGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLEAMQERQV 127
           FTPDLLP+D+ G+ ++++K  +F FKKGPVFT++LLADEINRA P+TQSALLEAM E QV
Sbjct: 63  FTPDLLPTDLTGLYIYDRKKEDFVFKKGPVFTDVLLADEINRATPRTQSALLEAMAEGQV 122

Query: 128 TIEGNTYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPSKEEEKEILKRRI 187
           T++G T++L   F VIATQNPIE EGT+PLPEAQLDRF++ +++GYP +E E ++L  + 
Sbjct: 123 TVDGVTHRLSERFFVIATQNPIEYEGTFPLPEAQLDRFMICVKMGYPDEEAEIQMLTSQ- 181

Query: 188 ERKMDDVEINTVLSPEDILRMQREIEEVYVSDAIIEYITSLVWATREDKREIEVGVSPRG 247
           E++    ++  V++P+++  +Q+++  V+VSD + +YI  +  ATR +   + +G+SPRG
Sbjct: 182 EKEHPISQLEPVMNPDELSELQKKVRNVFVSDEVKKYIVDIASATR-NHPSLLLGMSPRG 240

Query: 248 SLALLKLSRAYAAIEGRDYVIPDDVKAVAVPALSHRIILKRELWYMRIRQEDIIKKILEK 307
           S+AL+  S A A ++GRD+ +PDDVK  AV  + HR+I   E    R ++EDI+++IL++
Sbjct: 241 SIALMHFSMALAFMDGRDFTLPDDVKRAAVYVIPHRVIQSAESKLKREKKEDIVREILDR 300

Query: 308 VPVPK 312
           V V K
Sbjct: 301 VKVVK 305


>pir||D72767 hypothetical protein APE0127 - Aeropyrum pernix (strain K1)
           >gi|5103517|dbj|BAA79038.1| (AP000058) 314aa long
           hypothetical protein [Aeropyrum pernix]
           Length = 314
           
 Score =  307 bits (777), Expect = 1e-82
 Identities = 152/303 (50%), Positives = 217/303 (71%), Gaps = 6/303 (1%)

Query: 9   KVLEEVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALGLEFRRVQF 68
           +V  EV + ++GK+  +KL LA+M+A GH+L+E +PG+AKT +AK+ A A GL F R+QF
Sbjct: 18  RVKREVARFVIGKEREVKLALATMIAKGHLLVEGVPGVAKTTLAKALAGAFGLRFSRIQF 77

Query: 69  TPDLLPSDILGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLEAMQERQVT 128
           TPD LPSD++G +V+      F F++GPVF N++LADE+NRA P+TQSA LEAMQE QVT
Sbjct: 78  TPDTLPSDVIGTHVYVGNG--FVFRRGPVFANVVLADEVNRANPRTQSAFLEAMQEGQVT 135

Query: 129 IEGNTYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPSKEEEKEILKRRIE 188
           + G T++LP PFIV+AT NPIE EG YPLPEAQLDRF+ R+R+GYP++ EE +I+++  E
Sbjct: 136 VWGETHRLPSPFIVLATMNPIELEGVYPLPEAQLDRFMARIRLGYPTRVEEIKIIEKGDE 195

Query: 189 RKMDDVEINTVLSPEDILRMQREIEEVYVSDAIIEYITSLVWATREDKREIEVGVSPRGS 248
             ++D+ +    SPED+ R+Q     +YV   ++EYI  +V  TR  + E+E+G SPR  
Sbjct: 196 --VEDLNVEPAASPEDLKRLQDTARRIYVDRKLVEYIADIVRETRRIE-EVEIGASPRAG 252

Query: 249 LALLKLSRAYAAIEGRDYVIPDDVKAVAVPALSHRIILKRELWYMRIRQEDIIKKILEKV 308
           + +LKLSRA A + GRD+  PDDVK  A  AL HR+ L R+++  +   E +++ +L+KV
Sbjct: 253 IHILKLSRALALMSGRDFATPDDVKEAARAALPHRLKL-RKVYISKHSSEGLVEDVLKKV 311

Query: 309 PVP 311
           P P
Sbjct: 312 PPP 314


>dbj|BAB04450.1| (AP001509) unknown conserved protein [Bacillus halodurans]
           Length = 308
           
 Score =  305 bits (772), Expect = 6e-82
 Identities = 145/308 (47%), Positives = 220/308 (71%), Gaps = 4/308 (1%)

Query: 8   QKVLEEVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALGLEFRRVQ 67
           Q++L+++ + I+G+   ++L+L + LA GH+L+E +PG+ KT M +  A     +F+RVQ
Sbjct: 2   QQLLQQMDQVIIGQQKNIRLLLTAFLAGGHVLLEGVPGIGKTKMVRELADLTDGDFKRVQ 61

Query: 68  FTPDLLPSDILGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLEAMQERQV 127
           FTPD++PSD+ G  +FN K  +F+  KGPVFTN+LLADEINR PP+TQ+ALLEAM+ERQV
Sbjct: 62  FTPDMMPSDVTGNVIFNSKDNDFQMVKGPVFTNLLLADEINRTPPRTQAALLEAMEERQV 121

Query: 128 TIEGNTYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPSKEEEKEILKRRI 187
           TI+G TYQLP PF V+ATQNPIE EGTYPLPEAQLDRFL +L V YPS E E +I+K  +
Sbjct: 122 TIQGETYQLPDPFFVVATQNPIEYEGTYPLPEAQLDRFLFKLEVTYPSLEAELQIVKGHV 181

Query: 188 E---RKMDDVEINTVLSPEDILRMQREIEEVYVSDAIIEYITSLVWATREDKREIEVGVS 244
                + ++ +  +  S  ++ ++++++++V V D+++EY+ +++  TRED+R +  G S
Sbjct: 182 PFFVEQGNETDGRSAFSLTELRKLRQQLQQVVVEDSLMEYMVTIIRKTREDQRVMN-GAS 240

Query: 245 PRGSLALLKLSRAYAAIEGRDYVIPDDVKAVAVPALSHRIILKRELWYMRIRQEDIIKKI 304
           PR  +AL+  +RA+A ++GR +V PDD+K + VPAL HR+ L  ++       +  I++ 
Sbjct: 241 PRAGIALMMAARAWALLDGRQFVTPDDIKTITVPALRHRLQLTPQVELEGETSDHFIQET 300

Query: 305 LEKVPVPK 312
           L  VPVP+
Sbjct: 301 LASVPVPR 308


>pir||D75460 MoxR-related protein - Deinococcus radiodurans (strain R1)
           >gi|6458637|gb|AAF10492.1|AE001944_3 (AE001944)
           MoxR-related protein [Deinococcus radiodurans]
           Length = 354
           
 Score =  300 bits (760), Expect = 1e-80
 Identities = 155/305 (50%), Positives = 215/305 (69%), Gaps = 2/305 (0%)

Query: 7   AQKVLEEVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALGLEFRRV 66
           A +++  V + +VGK++V +L LA++LA GH+L+ED PG  KT++A++ A +LGL+FRRV
Sbjct: 21  AAEIIANVARVLVGKEDVTRLALAAILAGGHVLLEDAPGTGKTVLARALAASLGLDFRRV 80

Query: 67  QFTPDLLPSDILGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLEAMQERQ 126
           QFTPDLLPSD+ GV+VF   T  FEF  GP+FT ILLADEINRA PKTQSALLEAM E Q
Sbjct: 81  QFTPDLLPSDVTGVSVFRPATGTFEFVPGPIFTGILLADEINRATPKTQSALLEAMGEGQ 140

Query: 127 VTIEGNTYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPSKEEEKEILKRR 186
           V+  G T++LP+PF+VIATQNP+E EGTY LPEAQLDRFL+RL VGYPS E+E E+L R 
Sbjct: 141 VSESGVTHRLPQPFVVIATQNPVEHEGTYRLPEAQLDRFLLRLSVGYPSLEQEVEMLARL 200

Query: 187 IERKMDDVEINTVLSPEDILRMQREIEEVYVSDAIIEYITSLVWATREDKREIEVGVSPR 246
            ER     ++  V +P D+L  Q ++++V VS  +  Y+ +L   +R+   ++ +G  PR
Sbjct: 201 QERHPLQ-DLRAVAAPADLLAAQAQVQQVTVSSDVRRYLAALAARSRQHP-QVTLGGGPR 258

Query: 247 GSLALLKLSRAYAAIEGRDYVIPDDVKAVAVPALSHRIILKRELWYMRIRQEDIIKKILE 306
            SLAL  +++A A  +GR +V PDDV+  A   L+HR+ L  E     +   D+++++L 
Sbjct: 259 ASLALQGVAQALAWTQGRTFVTPDDVQQAAPGVLAHRLSLGIEARMQGLSAADVVREVLA 318

Query: 307 KVPVP 311
             PVP
Sbjct: 319 AEPVP 323


>pir||E70792 probable regulatory protein - Mycobacterium tuberculosis  (strain
           H37RV) >gi|2960116|emb|CAA18014.1| (AL022121) moxR2
           [Mycobacterium tuberculosis]
           Length = 358
           
 Score =  300 bits (759), Expect = 2e-80
 Identities = 153/302 (50%), Positives = 210/302 (68%), Gaps = 3/302 (0%)

Query: 13  EVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALGLEFRRVQFTPDL 72
           EV KA+VG+D V+  ++ ++L  GH+L+E +PG+AKTL+ ++ + AL LEF+RVQFTPDL
Sbjct: 58  EVAKAVVGQDGVISGLVIALLCRGHVLLEGVPGVAKTLIVRAMSAALQLEFKRVQFTPDL 117

Query: 73  LPSDILGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLEAMQERQVTIEGN 132
           +P D+ G  V++ +T EF F+ GPVFTN+LLADEINR PPKTQ+ALLEAM+ERQV++EG 
Sbjct: 118 MPGDVTGSLVYDARTAEFVFRPGPVFTNLLLADEINRTPPKTQAALLEAMEERQVSVEGE 177

Query: 133 TYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPSKEEEKEILKRRIE--RK 190
              LP PFIV ATQNPIE EGTY LPEAQLDRFL++L V  P+++ E  IL R       
Sbjct: 178 PKPLPNPFIVAATQNPIEYEGTYQLPEAQLDRFLLKLNVTLPARDSEIAILDRHAHGFDP 237

Query: 191 MDDVEINTVLSPEDILRMQREIEEVYVSDAIIEYITSLVWATREDKREIEVGVSPRGSLA 250
            D   IN V  P ++   +  +  V V++ ++ YI  +V ATR     +++GVSPRG+ A
Sbjct: 238 RDLSAINPVAGPAELAAGREAVRHVLVANEVLGYIVDIVGATRSSP-ALQLGVSPRGATA 296

Query: 251 LLKLSRAYAAIEGRDYVIPDDVKAVAVPALSHRIILKRELWYMRIRQEDIIKKILEKVPV 310
           LL  +R++A + GRDYV PDDVKA+A P L HR++L+ E        + ++  IL  VPV
Sbjct: 297 LLGTARSWAWLSGRDYVTPDDVKAMARPTLRHRVMLRPEAELEGATPDGVLDGILASVPV 356

Query: 311 PK 312
           P+
Sbjct: 357 PR 358


>pir||H70321 conserved hypothetical protein aq_240 - Aquifex aeolicus
           >gi|2982960|gb|AAC06575.1| (AE000680) hypothetical
           protein [Aquifex aeolicus]
           Length = 300
           
 Score =  300 bits (759), Expect = 2e-80
 Identities = 150/302 (49%), Positives = 211/302 (69%), Gaps = 7/302 (2%)

Query: 10  VLEEVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALGLEFRRVQFT 69
           ++ EV K I GK+ V+K  L  +L+ GH+LIED+PG  KT +A + A+ LGL F R+QFT
Sbjct: 6   IISEVSKVIKGKEEVIKNSLVCLLSGGHLLIEDVPGTGKTTLALALARVLGLSFSRIQFT 65

Query: 70  PDLLPSDILGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLEAMQERQVTI 129
            DLLPSDI GV+VFNQKT EFEFKKGP+F+N++LADEINR  PK QSALLEAM E+QV++
Sbjct: 66  SDLLPSDITGVSVFNQKTREFEFKKGPIFSNVVLADEINRGTPKVQSALLEAMAEKQVSV 125

Query: 130 EGNTYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPSKEEEKEILKRRIER 189
           +GNTY+LP PF VIATQNPIE  GTYPLPEAQLDRF +++ +GYPS+E+E +I+ + I  
Sbjct: 126 DGNTYKLPEPFFVIATQNPIEYYGTYPLPEAQLDRFTMKISMGYPSEEDEVQIV-QGINP 184

Query: 190 KMDDVEINTVLSPEDILRMQREIEEVYVSDAIIEYITSLVWATREDKREIEVGVSPRGSL 249
                 +N + SPE+++R   E++E+YVS  +  +I ++    R     I +GVS RG +
Sbjct: 185 MEKVSSLNVLSSPEEVIRTVNEVKEIYVSPEVARFIVNIGNEVRNHPSVI-LGVSTRGLI 243

Query: 250 ALLKLSRAYAAIEGRDYVIPDDVKAVAVPALSHRIILKRELWYMRIRQEDIIKKILEKVP 309
            L   SRA A    RD+V+P+DV  +    + HRI ++       ++ E ++K+++ +VP
Sbjct: 244 HLANASRALAYFRERDFVVPEDVLDLLKYVIPHRIKVRE-----GVKAEAVLKEVISRVP 298

Query: 310 VP 311
           +P
Sbjct: 299 IP 300


>pir||T34964 probable regulatory protein - Streptomyces coelicolor
           >gi|5689966|emb|CAB52003.1| (AL109663) putative
           regulatory protein [Streptomyces coelicolor A3(2)]
           Length = 337
           
 Score =  298 bits (756), Expect = 4e-80
 Identities = 147/305 (48%), Positives = 216/305 (70%), Gaps = 4/305 (1%)

Query: 8   QKVLEEVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALGLEFRRVQ 67
           ++V   V+  I GK  V++L L  +LA+GH+LIED+PG+ KT++AK+ A+++    RR+Q
Sbjct: 10  ERVRGSVEDVIEGKPEVVRLSLTVLLAEGHLLIEDVPGVGKTMLAKALARSIDCSVRRIQ 69

Query: 68  FTPDLLPSDILGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLEAMQERQV 127
           FTPDLLPSDI GV++++Q+  +FEFK G +F  +++ DEINRA PKTQSALLE+M+ERQV
Sbjct: 70  FTPDLLPSDITGVSIWDQQRRDFEFKPGAIFAQVVIGDEINRASPKTQSALLESMEERQV 129

Query: 128 TIEGNTYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPSKEEEKEILK-RR 186
           TI+G TY+LP PF+V+ATQNP+E EGTYPLPEAQ DRF+ R+ +GYPS E E ++L    
Sbjct: 130 TIDGQTYELPSPFMVVATQNPVEMEGTYPLPEAQRDRFMARVSIGYPSPEAELQMLDVHG 189

Query: 187 IERKMDDVEINTVLSPEDILRMQREIEEVYVSDAIIEYITSLVWATREDKREIEVGVSPR 246
               +DD++   V    DIL++   +  V+V+D +  Y   LV ATR    ++ +G SPR
Sbjct: 190 GASPLDDLQ--PVAHAHDILKLIEAVRGVHVADPVRRYAVDLVAATRTHP-DLRLGASPR 246

Query: 247 GSLALLKLSRAYAAIEGRDYVIPDDVKAVAVPALSHRIILKRELWYMRIRQEDIIKKILE 306
            +L LL+ ++A AA+ GRDY +PDDV+A+AV  L+HR++   +    R   E ++++IL+
Sbjct: 247 ATLHLLRAAKASAALSGRDYALPDDVQALAVAVLAHRLLPTAQAQLNRRTAEQVVQEILQ 306

Query: 307 KVPVP 311
           +  VP
Sbjct: 307 RTAVP 311


>emb|CAB90929.1| (AL355774) putative regulatory protein [Streptomyces coelicolor
           A3(2)]
           Length = 329
           
 Score =  298 bits (755), Expect = 5e-80
 Identities = 151/315 (47%), Positives = 213/315 (66%), Gaps = 5/315 (1%)

Query: 2   NVQVKAQKVLEEVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALGL 61
           N +   + +  E+ KA+VG+D  +  ++ ++L  GH+L+E +PG+AKTL+ ++ A A  L
Sbjct: 16  NARAALEALRAEIAKAVVGQDAAVTGLVVALLCRGHVLLEGVPGVAKTLLVRTLAAATEL 75

Query: 62  EFRRVQFTPDLLPSDILGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLEA 121
           + +RVQFTPDL+PSD+ G  V++ +T EF F+ GPVFTN+LLADEINR PPKTQS+LLEA
Sbjct: 76  DTKRVQFTPDLMPSDVTGSLVYDARTTEFSFQPGPVFTNLLLADEINRTPPKTQSSLLEA 135

Query: 122 MQERQVTIEGNTYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPSKEEEKE 181
           M+ERQVT++G    LP PF+V ATQNP+E EGTYPLPEAQLDRFL++L V  P++++E +
Sbjct: 136 MEERQVTVDGTPRLLPEPFLVAATQNPVEYEGTYPLPEAQLDRFLLKLTVPLPTRQDEID 195

Query: 182 ILKRRI----ERKMDDVEINTVLSPEDILRMQREIEEVYVSDAIIEYITSLVWATREDKR 237
           +L R       R +    +  V S  D+   + E  +  VS  I  Y+  +  ATRE   
Sbjct: 196 VLTRHAAGFNPRDLRAAGVRPVASAADLEAARAEAAKTTVSPEITAYVVDICRATRESP- 254

Query: 238 EIEVGVSPRGSLALLKLSRAYAAIEGRDYVIPDDVKAVAVPALSHRIILKRELWYMRIRQ 297
            + +GVSPRG+ ALL  +RA+A + GRDYV PDDVKA+A+P L HR+ L+ E     +  
Sbjct: 255 SLTLGVSPRGATALLSTARAWAWLTGRDYVTPDDVKALALPTLRHRVQLRPEAEMEGVTA 314

Query: 298 EDIIKKILEKVPVPK 312
           + +I  IL  VPVP+
Sbjct: 315 DSVINAILAHVPVPR 329


>pir||F72606 probable methanol dehydrogenase regulator APE1317 - Aeropyrum
           pernix (strain K1) >gi|5104994|dbj|BAA80308.1|
           (AP000061) 306aa long hypothetical methanol
           dehydrogenase regulator [Aeropyrum pernix]
           Length = 306
           
 Score =  295 bits (747), Expect = 5e-79
 Identities = 148/303 (48%), Positives = 211/303 (68%), Gaps = 3/303 (0%)

Query: 9   KVLEEVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALGLEFRRVQF 68
           ++ EEV K IVGK+  ++L+LA++ A GH+L+E +PG+AKT MA++ A+A GL F R+QF
Sbjct: 7   RISEEVSKVIVGKEREIRLVLAALAARGHVLLEGVPGVAKTTMARAIARATGLRFSRIQF 66

Query: 69  TPDLLPSDILGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLEAMQERQVT 128
           TPD+LPSD++G  V++Q+T EF F++GPVF N++LADE+NRA P+TQSA LEAMQE QVT
Sbjct: 67  TPDMLPSDVIGTMVYDQRTGEFVFRRGPVFANVVLADEVNRANPRTQSAFLEAMQEGQVT 126

Query: 129 IEGNTYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPSKEEEKEILKRRIE 188
           + G T++LP PFIV+AT NPIE EG YPLPEAQLDRF+ R+ VG+PS EE  EI+++   
Sbjct: 127 VWGETHRLPSPFIVLATMNPIELEGVYPLPEAQLDRFMARVVVGHPSLEELVEIMEK--Y 184

Query: 189 RKMDDVEINTVLSPEDILRMQREIEEVYVSDAIIEYITSLVWATREDKREIEVGVSPRGS 248
           R + +  +  V  PEDI+  Q  + +V+V   I  YI  +V  T +    + +G SPR +
Sbjct: 185 RSITEFPVEPVARPEDIVAAQEAVWKVHVDKNIKLYIARIVEETHKHP-GVSLGGSPRAA 243

Query: 249 LALLKLSRAYAAIEGRDYVIPDDVKAVAVPALSHRIILKRELWYMRIRQEDIIKKILEKV 308
           L+++ L+R  A ++G  YV PD VK  A  AL HR+IL  E     ++ E +++ +L  V
Sbjct: 244 LSIMMLARGLALLDGLGYVTPDHVKEAARAALPHRLILTTEAKLEGLKPESVVEDVLSSV 303

Query: 309 PVP 311
             P
Sbjct: 304 ETP 306


>emb|CAC12049.1| (AL445065) regulatory protein moxR related protein [Thermoplasma
           acidophilum]
           Length = 319
           
 Score =  287 bits (727), Expect = 1e-76
 Identities = 147/316 (46%), Positives = 214/316 (67%), Gaps = 10/316 (3%)

Query: 2   NVQVKAQKVLEEVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALGL 61
           N++     + E + K ++G   +++ M  ++L   HIL+E +PGLAKT++A  FA+   +
Sbjct: 9   NLRNTVISIEESIGKRVIGSRRIVRFMFIALLTGNHILMEGVPGLAKTMLANEFARHTRM 68

Query: 62  EFRRVQFTPDLLPSDILGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLEA 121
           +FRR+QFTPD+LPSD+ G  +FN ++ + EFK+GP+F N++LADEINR PPK QSALLEA
Sbjct: 69  KFRRIQFTPDMLPSDVTGTIMFNIESRKMEFKEGPIFANVILADEINRTPPKVQSALLEA 128

Query: 122 MQERQVTIEGNTYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPSKEEEKE 181
           M+E QVTI G T+ LP+PF VIATQNPIEQEGT+PL EA +DRFL R  + YPS+E+E  
Sbjct: 129 MEETQVTIGGETHSLPKPFFVIATQNPIEQEGTFPLAEALMDRFLFRYYLEYPSREDELN 188

Query: 182 ILKRRIERKMDDVEINTVLSPEDILRMQREIEEVYVSDAIIEYITSLVWATREDKREIEV 241
           IL      K DD  +  VL P++I+  + +++ VY+S+ I +Y+  L+  TRE+   + +
Sbjct: 189 ILNS--IGKYDDPSL--VLMPDEIIEFRSQVDNVYISEEIKQYLVDLMRRTRENDL-VYL 243

Query: 242 GVSPRGSLALLKLSRAYAAIEGRDYVIPDDVKAVAVPALSHRIILKRELWY-----MRIR 296
           G SPR +   +K +RA A I GR YVIP+D+  +A   L+HR+ILK E         ++ 
Sbjct: 244 GASPRTTAKYMKAARANALISGRSYVIPEDITFMAFEILNHRLILKPEAIMDETDDPKLI 303

Query: 297 QEDIIKKILEKVPVPK 312
            + II ++L +VPVPK
Sbjct: 304 VKRIIDRVLSEVPVPK 319


>pir||B70874 probable moxR protein - Mycobacterium tuberculosis (strain H37RV)
           >gi|2791413|emb|CAA16007.1| (AL021184) moxR
           [Mycobacterium tuberculosis]
           Length = 377
           
 Score =  286 bits (723), Expect = 3e-76
 Identities = 144/313 (46%), Positives = 207/313 (66%), Gaps = 11/313 (3%)

Query: 8   QKVLEEVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALGLEFRRVQ 67
           ++ + EVK+ IVG+D +++ ML  +L+ GH+L+E +PG+AKTL  ++FA+ +G  F R+Q
Sbjct: 44  ERAIFEVKRIIVGQDQLVERMLVGLLSKGHVLLEGVPGVAKTLAVETFARVVGGTFSRIQ 103

Query: 68  FTPDLLPSDILGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLEAMQERQV 127
           FTPDL+P+DI+G  ++ Q   EF+ + GPV  N LLADEINRAP K QSALLE MQER V
Sbjct: 104 FTPDLVPTDIIGTRIYRQGREEFDTELGPVVANFLLADEINRAPAKVQSALLEVMQERHV 163

Query: 128 TIEGNTYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPSKEEEKEILKRRI 187
           +I G T+ +P PF+V+ATQNPIE EG YPLPEAQ DRFL ++ VGYPS EEE+EI+ R  
Sbjct: 164 SIGGRTFPMPSPFLVMATQNPIEHEGVYPLPEAQRDRFLFKINVGYPSPEEEREIIYR-- 221

Query: 188 ERKMDDVEINTVLSPEDILRMQREIEEVYVSDAIIEYITSLVWATRED--------KREI 239
              +   +   +LS  D+LR+Q      +V  A+++Y+  +V+ATR+         K  +
Sbjct: 222 -MGVTPPQAKQILSTGDLLRLQEIAANNFVHHALVDYVVRVVFATRKPEQLGMNDVKSWV 280

Query: 240 EVGVSPRGSLALLKLSRAYAAIEGRDYVIPDDVKAVAVPALSHRIILKRELWYMRIRQED 299
             G SPR SL ++  +R+ A + GRDYVIP DV  V    L HR++L  +     I  E 
Sbjct: 281 AFGASPRASLGIIAAARSLALVRGRDYVIPQDVIEVIPDVLRHRLVLTYDALADEISPEI 340

Query: 300 IIKKILEKVPVPK 312
           +I ++L+ V +P+
Sbjct: 341 VINRVLQTVALPQ 353


>pir||C83106 conserved hypothetical protein PA4322 [imported] - Pseudomonas
           aeruginosa (strain PAO1)
           >gi|9950546|gb|AAG07710.1|AE004848_9 (AE004848)
           conserved hypothetical protein [Pseudomonas aeruginosa]
           Length = 335
           
 Score =  284 bits (720), Expect = 7e-76
 Identities = 138/311 (44%), Positives = 217/311 (69%), Gaps = 7/311 (2%)

Query: 7   AQKVLEEVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALGLEFRRV 66
           AQ +  E++KA++G+  V+  +L ++LA GH+L+E +PGL KTL+ ++ A+     F R+
Sbjct: 26  AQALRTELQKALIGQGAVIDDVLTALLAGGHVLVEGVPGLGKTLLVRALARCFDGGFARI 85

Query: 67  QFTPDLLPSDILGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLEAMQERQ 126
           QFTPDL+PSD+ G  V++  + +F+ +KGPVFT++LLADEINRAP KTQ+ALLE MQERQ
Sbjct: 86  QFTPDLMPSDVTGHAVYDLASEQFKLRKGPVFTHLLLADEINRAPAKTQAALLEVMQERQ 145

Query: 127 VTIEGNTYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPSKEEEKEILKRR 186
           VT+EG    +P+PF+V+ATQNPIEQEGTYPLPEA+LDRF+++LR+ YP+ E E++ L R+
Sbjct: 146 VTLEGRALPVPQPFMVLATQNPIEQEGTYPLPEAELDRFMLKLRIDYPA-EAEEQTLVRQ 204

Query: 187 IERK-----MDDVEINTVLSPEDILRMQREIEEVYVSDAIIEYITSLVWATREDKREIEV 241
           + R      +D   +  +L  +D+L +QR   ++ + D +++Y   L   TR +   + +
Sbjct: 205 VTRSARSDMLDVANLRPLLKDKDVLALQRIASDLPIDDQVLDYAVRLARTTR-NWPGLAL 263

Query: 242 GVSPRGSLALLKLSRAYAAIEGRDYVIPDDVKAVAVPALSHRIILKRELWYMRIRQEDII 301
           G  PR S+AL++  RA A + G ++V+PDD+K  A+  L HR+ L  EL    +  + ++
Sbjct: 264 GAGPRASIALVRCGRARALLRGGEFVVPDDIKGCALAVLRHRVRLSPELDIEGLSVDQVL 323

Query: 302 KKILEKVPVPK 312
           +++L++VP P+
Sbjct: 324 QQLLDQVPAPR 334


>pir||S75782 methanol dehydrogenase regulatory protein - Synechocystis sp.
           (strain PCC 6803) >gi|1001272|dbj|BAA10517.1| (D64003)
           MoxR [Synechocystis sp.]
           Length = 303
           
 Score =  283 bits (717), Expect = 2e-75
 Identities = 142/300 (47%), Positives = 217/300 (72%), Gaps = 7/300 (2%)

Query: 12  EEVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALGLEFRRVQFTPD 71
           + + + IVGKD  ++L+L ++L+ GH L+ED+PG+ KTL+AKS A+++  +F+RVQ TPD
Sbjct: 10  QNLSQTIVGKDEAIRLVLVALLSGGHALLEDVPGVGKTLLAKSLARSINGKFQRVQCTPD 69

Query: 72  LLPSDILGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLEAMQERQVTIEG 131
           LLP+DI G N++N  + EFEF  GP F NILLADEINRA P+TQ+ALLE M+E+QVT++G
Sbjct: 70  LLPTDITGTNIWNPSSREFEFLPGPAFANILLADEINRATPRTQAALLEVMEEKQVTVDG 129

Query: 132 NTYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPSKEEEKEILKRRIERKM 191
            T  +P PF VIATQNPIE +GT+PLPEAQLDRF + L +GYPS+ EE ++L+R+   + 
Sbjct: 130 ETRLVPHPFFVIATQNPIEYQGTFPLPEAQLDRFALSLSLGYPSEAEELKMLQRQQNPEA 189

Query: 192 DDV-EINTVLSPEDILRMQREIEEVYVSDAIIEYITSLVWATREDKREIEVGVSPRGSLA 250
             V ++ + +S E++  +Q+ + +V +++ + +Y+  LV A+R D+ ++ +GVSPRG+ A
Sbjct: 190 IAVGDLESCISLEEVEALQKAVRQVKLTEDLQQYLLRLVRASRTDE-DVTLGVSPRGTTA 248

Query: 251 LLKLSRAYAAIEGRDYVIPDDVKAVAVPALSHRIILKRELWYMRIRQEDIIKKILEKVPV 310
           L + ++A+A +E RDY I DDVK VA   L+HR+I            + I++++L+ VP+
Sbjct: 249 LQRATQAFAFLEERDYAIDDDVKFVAPHVLAHRLIPASGK-----DPKAILQRLLDSVPI 303


>pir||S74593 MorR protein - Synechocystis sp. (strain PCC 6803)
           >gi|1651818|dbj|BAA16745.1| (D90900) MorR protein
           [Synechocystis sp.]
           Length = 314
           
 Score =  283 bits (716), Expect = 2e-75
 Identities = 144/299 (48%), Positives = 213/299 (71%), Gaps = 5/299 (1%)

Query: 18  IVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALGLEFRRVQFTPDLLPSDI 77
           +VG+ ++++ +L ++LA GH++IE +PG  KTL+ K  A+++  +FRRVQ TPD+LPSD+
Sbjct: 17  LVGQPHLIQELLVALLAGGHVIIEGVPGTGKTLLVKLLAQSIQSQFRRVQLTPDMLPSDM 76

Query: 78  LGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLEAMQERQVTIEGNTYQLP 137
           +GVNVF+     F  K+GPVFT ILLADEINR PPKTQSALLEAM+E+QVT++G+TY LP
Sbjct: 77  VGVNVFDFNQQAFSLKQGPVFTEILLADEINRTPPKTQSALLEAMEEQQVTLDGHTYALP 136

Query: 138 RPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPSKEEEKEIL---KRRIERKMDDV 194
             F V+ATQNP+E EGTYPLPEAQLDRFL +L V YP     K++L   ++    +  D+
Sbjct: 137 PLFWVVATQNPLEFEGTYPLPEAQLDRFLFKLVVDYPPPAAAKQMLVNFQQGFHAQRQDL 196

Query: 195 E-INTVLSPEDILRMQREIEEVYVSDAIIEYITSLVWATREDKREIEVGVSPRGSLALLK 253
           E +  + + E+IL  +R +E++ V + +++Y+ +LV  TR    +I +G SPR SL  L+
Sbjct: 197 EQLTAIATVEEILASRRSVEDIAVDEKLLDYLLALVEKTRYHP-DILIGASPRASLRWLQ 255

Query: 254 LSRAYAAIEGRDYVIPDDVKAVAVPALSHRIILKRELWYMRIRQEDIIKKILEKVPVPK 312
            ++A A + G++Y++PD++K VA P L HR+IL+ E     I  +++I  ILE+ PVP+
Sbjct: 256 AAKADAWLNGQEYLLPDNLKTVAPPLLRHRLILRPEAQLDGIGIDEVITAILEQTPVPR 314


>pir||H70121 methanol dehydrogenase regulator (moxR) homolog - Lyme disease
           spirochete >gi|2688061|gb|AAC66559.1| (AE001128)
           methanol dehydrogenase regulator (moxR) [Borrelia
           burgdorferi]
           Length = 337
           
 Score =  282 bits (715), Expect = 3e-75
 Identities = 149/311 (47%), Positives = 212/311 (67%), Gaps = 8/311 (2%)

Query: 9   KVLEEVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALGLEFRRVQF 68
           K   EV   ++G+  ++  +L  +L DGH+L+E +PGLAKTL  ++ +  L LEF+R+QF
Sbjct: 27  KFRREVATRVLGQKEMIDAILMGLLTDGHVLLEGVPGLAKTLAIQTVSDVLDLEFKRIQF 86

Query: 69  TPDLLPSDILGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLEAMQERQVT 128
           TPDLLPSD+ G  V+   T  F+ +KGPVF+N++LADEINRAP K QSALLEAM ERQVT
Sbjct: 87  TPDLLPSDLTGNMVYKSATGTFKVRKGPVFSNVILADEINRAPAKVQSALLEAMGERQVT 146

Query: 129 IEGNTYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPSKEEEKEILK-RRI 187
           +   T++LP PF V+ATQNPIEQEGTY LPE+QLDRFL+++ V YPS ++E  +LK   +
Sbjct: 147 LGDETHRLPDPFFVLATQNPIEQEGTYNLPESQLDRFLLKVNVHYPSVQDEVRLLKIFSV 206

Query: 188 ERKMDDVEINTVLSPEDILRMQREIEEVYVSDAIIEYITSLVWATRE-DKRE------IE 240
           + +++++++  V++   +  ++R +  V V D I+ YI +L+ A+RE DK+       IE
Sbjct: 207 DGRLENIKVAKVMNAYSLADIKRTVGRVKVDDKIMLYIVTLISASRERDKKTYPFAKYIE 266

Query: 241 VGVSPRGSLALLKLSRAYAAIEGRDYVIPDDVKAVAVPALSHRIILKRELWYMRIRQEDI 300
            G SPR SL+LLK +R  A  EGR +V+P+DVKAVA   L HRI    E     +  +DI
Sbjct: 267 FGASPRASLSLLKCARVNALYEGRIFVLPEDVKAVAYSVLRHRITPSYEAEVEEMSIDDI 326

Query: 301 IKKILEKVPVP 311
           I+ +L  V +P
Sbjct: 327 IRMLLSAVALP 337


>pir||G82635 methanol dehydrogenase regulatory protein XF1813 [imported] -
           Xylella fastidiosa (strain 9a5c)
           >gi|9106890|gb|AAF84619.1|AE004002_9 (AE004002) methanol
           dehydrogenase regulatory protein [Xylella fastidiosa]
           Length = 317
           
 Score =  281 bits (711), Expect = 8e-75
 Identities = 134/287 (46%), Positives = 210/287 (72%), Gaps = 2/287 (0%)

Query: 3   VQVKAQKVLEEVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALGLE 62
           +++   +   +V   ++GK+  ++L   ++L+ GH+L+EDLPGL KT +A + A +LGL 
Sbjct: 14  LRLSLDEAQNQVNTLLLGKEQEVRLAFVALLSGGHLLLEDLPGLGKTTLAHALASSLGLT 73

Query: 63  FRRVQFTPDLLPSDILGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLEAM 122
           FRRVQFT DLLP+D+LG++V+N +T +FEF  GPVFT++LLADEINRAPP+TQSALLEAM
Sbjct: 74  FRRVQFTSDLLPADVLGISVYNTQTQQFEFHPGPVFTHVLLADEINRAPPRTQSALLEAM 133

Query: 123 QERQVTIEGNTYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPSKEEEKEI 182
            E+QVT++G T  L  PF VIATQNP++  GT+PLP++QLDRFL+RL +GYP+ E E+ +
Sbjct: 134 AEQQVTLDGITRSLSDPFFVIATQNPVDLYGTFPLPDSQLDRFLLRLSLGYPNAEAERTL 193

Query: 183 LKRRIERKMDDVEINTVLSPEDILRMQREIEEVYVSDAIIEYITSLVWATREDKREIEVG 242
           L     R++    +   L+  D++ +++ +  V+VSDA+IEY+ +L+  +R+ +  + VG
Sbjct: 194 LSGMDRRELLTHTLPR-LTEADVILLRKTVLGVHVSDALIEYVQALLLRSRQ-QSGVRVG 251

Query: 243 VSPRGSLALLKLSRAYAAIEGRDYVIPDDVKAVAVPALSHRIILKRE 289
           +SPR  +ALL+ ++AYA + GR++V+P+D++ + V    HR++ + E
Sbjct: 252 LSPRAGIALLRAAKAYALLSGREHVLPEDIQELFVSVAGHRLVPEAE 298


>pir||G83261 conserved hypothetical protein PA3070 [imported] - Pseudomonas
           aeruginosa (strain PAO1)
           >gi|9949177|gb|AAG06458.1|AE004731_6 (AE004731)
           conserved hypothetical protein [Pseudomonas aeruginosa]
           Length = 326
           
 Score =  277 bits (700), Expect = 2e-73
 Identities = 143/301 (47%), Positives = 206/301 (67%), Gaps = 8/301 (2%)

Query: 18  IVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALGLEFRRVQFTPDLLPSDI 77
           I+G++ ++  +L ++LADGH+L+E  PGLAKT   K  A+ L  EF R+QFTPDLLP+DI
Sbjct: 25  ILGQEKLVDRLLIALLADGHLLVEGAPGLAKTKAIKDLAEGLEAEFHRIQFTPDLLPADI 84

Query: 78  LGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLEAMQERQVTIEGNTYQLP 137
            G  ++  +T  F F++GP+F +++LADEINRAP K QSALLEAM ERQV++  +TY LP
Sbjct: 85  TGTEIYRPETGTFVFQQGPIFHHLVLADEINRAPAKVQSALLEAMAERQVSVGRSTYDLP 144

Query: 138 RPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPSKEEEKEILKR-RIERKMDDVEI 196
           + F+V+ATQNPIEQEGTYPLPEAQLDRFL+ +++GYP    E+ IL++ R E    +   
Sbjct: 145 QLFLVMATQNPIEQEGTYPLPEAQLDRFLMHVKIGYPEASVERRILQQARGEALNGEARP 204

Query: 197 NTVLSPEDILRMQREIEEVYVSDAIIEYITSLVWATREDKRE-------IEVGVSPRGSL 249
              ++ E I   ++EI  +Y++DA+ EY+  L+ ATR   +        I  G SPRGS+
Sbjct: 205 ERRVTQETIFAARQEILGLYMADAVEEYLVQLIMATRTPAKHDAELAEWISYGASPRGSI 264

Query: 250 ALLKLSRAYAAIEGRDYVIPDDVKAVAVPALSHRIILKRELWYMRIRQEDIIKKILEKVP 309
           AL + +RA+A + GRD+V P+D++AV    L HR+IL  E     I Q+ ++++IL+ V 
Sbjct: 265 ALDRCARAHAWLGGRDFVSPEDIQAVLFDVLRHRLILTFEAEAAGIDQDRVVQRILDVVA 324

Query: 310 V 310
           V
Sbjct: 325 V 325


>emb|CAB98184.1| (AJ276161) putative regulatory protein [Streptomyces sparsogenes]
           Length = 335
           
 Score =  275 bits (696), Expect = 4e-73
 Identities = 140/301 (46%), Positives = 201/301 (66%), Gaps = 2/301 (0%)

Query: 12  EEVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALGLEFRRVQFTPD 71
           + +++ + GK + ++L L  + ++GH+LIED+PG  KT +A+  A +L  ++ RVQFTPD
Sbjct: 32  DNIERVVKGKRDTVELALVCLFSEGHLLIEDVPGTGKTTLARCLAASLEADWHRVQFTPD 91

Query: 72  LLPSDILGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLEAMQERQVTIEG 131
           LLPSDI GV V+ Q T  FEF  GPVF NI+L DEINRA PKTQSA+LE M+ERQVT +G
Sbjct: 92  LLPSDITGVTVYRQNTGTFEFLPGPVFANIVLGDEINRASPKTQSAMLEVMEERQVTADG 151

Query: 132 NTYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPSKEEEKEILKRRIERKM 191
           +T+ +PRPF+VIATQN ++  GTYPLPEAQLDRFL+++ +GYP    E  +L     +  
Sbjct: 152 STHPVPRPFMVIATQNSVDMGGTYPLPEAQLDRFLMQVTLGYPDHASEVAVLSGAASQTS 211

Query: 192 DDVEINTVLSPEDILRMQREIEEVYVSDAIIEYITSLVWATREDKREIEVGVSPRGSLAL 251
            + ++ T+ +   I    +   ++ V+  + +Y+  +V ATR    E+ +G SPRGS+AL
Sbjct: 212 IE-QLPTIATGRHIAEFIQVARQIQVAPQLYDYLVRVVAATR-SLPEVRLGASPRGSVAL 269

Query: 252 LKLSRAYAAIEGRDYVIPDDVKAVAVPALSHRIILKRELWYMRIRQEDIIKKILEKVPVP 311
           L+  R  AA +GR Y +P+DVKA+A P L+HR+IL  E         D+I + L  VPVP
Sbjct: 270 LRAVRVRAASQGRTYALPEDVKALAGPVLAHRLILTPEAELSGRCGADVIAEALATVPVP 329

Query: 312 K 312
           +
Sbjct: 330 Q 330


>pir||H83287 conserved hypothetical protein PA2875 [imported] - Pseudomonas
           aeruginosa (strain PAO1)
           >gi|9948964|gb|AAG06263.1|AE004713_12 (AE004713)
           conserved hypothetical protein [Pseudomonas aeruginosa]
           Length = 305
           
 Score =  274 bits (694), Expect = 8e-73
 Identities = 140/274 (51%), Positives = 192/274 (69%), Gaps = 2/274 (0%)

Query: 11  LEEVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALGLEFRRVQFTP 70
           L+ V + ++GKD  ++L LA +LA GH+LIEDLPG+ KT ++ + A+ LGL F+R+QFT 
Sbjct: 9   LKAVDEILLGKDRQVRLALACLLARGHLLIEDLPGMGKTTLSHALARVLGLSFQRIQFTS 68

Query: 71  DLLPSDILGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLEAMQERQVTIE 130
           DLLP DILG +VF++ + +F F  GP+F  ++LADEINRA PK+QSALLEAM+E QVTIE
Sbjct: 69  DLLPGDILGTSVFDKDSGQFVFHPGPIFAELVLADEINRATPKSQSALLEAMEEGQVTIE 128

Query: 131 GNTYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPSKEEEKEILKRRIERK 190
           G T  LP PF VIATQNP  Q GT+ LPE+QLDRFL+RL +GYP +  E+ +L     R 
Sbjct: 129 GATRPLPEPFFVIATQNPASQGGTFSLPESQLDRFLMRLSLGYPGRAAERSLLLGEARRD 188

Query: 191 MDDVEINTVLSPEDILRMQREIEEVYVSDAIIEYITSLVWATREDKREIEVGVSPRGSLA 250
           +    +  +L    +   Q E+ ++  SDA+++Y+  LV ATR  +    +G+SPRGSLA
Sbjct: 189 LLP-RLEPLLDHAALAAFQAEVPKIRASDALVDYVLRLVEATR-TQPAFALGLSPRGSLA 246

Query: 251 LLKLSRAYAAIEGRDYVIPDDVKAVAVPALSHRI 284
           LL  +RA+A + GRDYVIP+DV+AV      HR+
Sbjct: 247 LLAAARAWALLAGRDYVIPEDVQAVLPAVAGHRL 280


>emb|CAA65298.1| (X96434) moxR [Borrelia burgdorferi] >gi|2689172|emb|CAA06007.1|
           (AJ003222) moxR [Borrelia burgdorferi]
           Length = 329
           
 Score =  273 bits (690), Expect = 2e-72
 Identities = 147/311 (47%), Positives = 209/311 (66%), Gaps = 9/311 (2%)

Query: 9   KVLEEVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALGLEFRRVQF 68
           K   EV   ++G+  ++  +L  +L DGH+L+E +PGLAKTL  ++ +  L LEF+R+QF
Sbjct: 20  KFRREVATRVLGQKEMIDAILMGLLTDGHVLLEGVPGLAKTLAIQTVSDVLDLEFKRIQF 79

Query: 69  TPDLLPSDILGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLEAMQERQVT 128
           TPDLLPSD+ G  V+   T  F+ +KGPVF+N++LADEINRAP K QSALLEAM ERQVT
Sbjct: 80  TPDLLPSDLTGNMVYKSATGTFKVRKGPVFSNVILADEINRAPAKVQSALLEAMGERQVT 139

Query: 129 IEGNTYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPSKEEEKEILK-RRI 187
           +   T++LP PF V+ATQNPIEQEGTY LPE+QLDRFL+++ V YPS ++E  +LK   +
Sbjct: 140 LGDETHRLPDPFFVLATQNPIEQEGTYNLPESQLDRFLLKVNVHYPSVQDEVRLLKIFSV 199

Query: 188 ERKMDDVEINTVLSPEDILRMQREIEEVYVSDAIIEYITSLVWATRE-DKRE------IE 240
           + +++++++  V++   +  ++R +  V V D I+  I   + A+RE DK+       IE
Sbjct: 200 DGRLENIKVAKVMNAYSLADIKRTVGRVKVDDKIM-LICYFISASRERDKKTYPFAKYIE 258

Query: 241 VGVSPRGSLALLKLSRAYAAIEGRDYVIPDDVKAVAVPALSHRIILKRELWYMRIRQEDI 300
            G SPR SL+LLK +R  A  EGR +V+P+DVKAVA   L HRI    E     +  +DI
Sbjct: 259 FGASPRASLSLLKCARVNALYEGRIFVLPEDVKAVAYSVLRHRITPSYEAEVEEMSIDDI 318

Query: 301 IKKILEKVPVP 311
           I+ +L  V +P
Sbjct: 319 IRMLLSAVALP 329


>pir||B75496 moxR protein - Deinococcus radiodurans (strain R1)
           >gi|6458321|gb|AAF10200.1|AE001920_3 (AE001920) moxR
           protein [Deinococcus radiodurans]
           Length = 320
           
 Score =  271 bits (686), Expect = 7e-72
 Identities = 144/303 (47%), Positives = 207/303 (67%), Gaps = 6/303 (1%)

Query: 9   KVLEEVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALGLEFRRVQF 68
           + LE++ + I+GK   L+L +A +LA GH+LIED PG+ KT +A++ A+ LGL FRRVQF
Sbjct: 24  RALEQLDQVILGKPTQLRLAVACLLARGHLLIEDQPGVGKTTLAQALARTLGLGFRRVQF 83

Query: 69  TPDLLPSDILGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLEAMQERQVT 128
           T DLLP+D+LGV++++  +  F ++ GP+F+ +LLADEINRA P+TQ ALLEAM+ERQV+
Sbjct: 84  TSDLLPADLLGVSIWDAASSTFRYQPGPIFSELLLADEINRATPRTQGALLEAMEERQVS 143

Query: 129 IEGNTYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPSKEEEKEILKRRIE 188
             G T  LP PF VIATQNP    GT PLPEAQLDRFL+ + +GYP    E+ +L+    
Sbjct: 144 EGGVTRPLPDPFFVIATQNPAAFVGTSPLPEAQLDRFLMTVTLGYPDARAERTLLETG-G 202

Query: 189 RKMDDVEINTVLSPEDILRMQREIEEVYVSDAIIEYITSLVWATREDKREIEVGVSPRGS 248
           R     E+  VL    +LR Q E++ V+ + A+++Y+  L  ATRE +  I  G+SPR  
Sbjct: 203 RGQSVRELPAVLDAPLLLRAQAEVDAVHAAPALLDYLQLLARATRE-QPAIASGLSPRAL 261

Query: 249 LALLKLSRAYAAIEGRDYVIPDDVKAVAVPALSHRIILKRELWYMRIRQEDIIKKILEKV 308
           LALL  +RA+A + GRD V+P+DV+AV     SHR++L+        R  D+I+++L++ 
Sbjct: 262 LALLAAARAWAYLAGRDMVLPEDVQAVFPALASHRLVLRDP----AARPGDVIRRLLDET 317

Query: 309 PVP 311
           P+P
Sbjct: 318 PIP 320


>pir||H82493 MoxR-related protein VCA0175 [imported] - Vibrio cholerae  (group
           O1 strain N16961) >gi|9657565|gb|AAF96088.1| (AE004357)
           MoxR-related protein [Vibrio cholerae]
           Length = 318
           
 Score =  263 bits (664), Expect = 3e-69
 Identities = 137/309 (44%), Positives = 202/309 (65%), Gaps = 8/309 (2%)

Query: 8   QKVLEEVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALGLEFRRVQ 67
           Q +   + + ++G+ + +  +L ++LADGHIL+E  PGLAKT   KS A  +  +F R+Q
Sbjct: 7   QTLQHYLNQQVIGQTDFINQLLIALLADGHILVEGPPGLAKTRAVKSLADCIEGDFHRIQ 66

Query: 68  FTPDLLPSDILGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLEAMQERQV 127
           FTPDLLP+D+ G +V+  +T EF F+ GP+F  ++LADEINRAP K Q+A+LEAM E+Q+
Sbjct: 67  FTPDLLPADLTGSDVYRPETGEFVFQSGPIFNALVLADEINRAPAKVQAAMLEAMAEKQI 126

Query: 128 TIEGNTYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPSKEEEKEILK-RR 186
           +    TY+LP  F+V+ATQNPIEQEGTYPLPEAQLDRFL+ L V YP+ E+E  IL+  R
Sbjct: 127 SAGRKTYRLPELFLVMATQNPIEQEGTYPLPEAQLDRFLLHLEVNYPNAEDELAILRLNR 186

Query: 187 IERKMDDVEINTVLSPEDILRMQREIEEVYVSDAIIEYITSLVWATRED-------KREI 239
            E K        +L+ + +   ++E+  V++++AI  Y+  LV ATR          + +
Sbjct: 187 GEAKGQQAINKPLLTQQQVFSARQEVLNVHMAEAIENYLVRLVMATRHPANYDAKLAQWL 246

Query: 240 EVGVSPRGSLALLKLSRAYAAIEGRDYVIPDDVKAVAVPALSHRIILKRELWYMRIRQED 299
            +GVSPR ++AL + +RA+A ++GRD+V PDDV+ +A   L HR++L  +     I    
Sbjct: 247 TMGVSPRATIALDRCARAHAWLQGRDFVTPDDVQVMAFSVLRHRLLLSYQAQAEGIHPNK 306

Query: 300 IIKKILEKV 308
           II  +L  V
Sbjct: 307 IISHLLSLV 315


>gb|AAC46196.1| (AF002133) transcriptional regulator [Mycobacterium avium]
           Length = 309
           
 Score =  214 bits (540), Expect = 9e-55
 Identities = 101/178 (56%), Positives = 135/178 (75%)

Query: 8   QKVLEEVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALGLEFRRVQ 67
           ++ + EVK+ IVG+D +++ ML  +L+ GH+L+E +PG+AK+L  ++FAK +G  F R+Q
Sbjct: 46  ERAIFEVKRIIVGQDQLVERMLVGLLSKGHVLLEGVPGVAKSLAVETFAKVVGGTFARIQ 105

Query: 68  FTPDLLPSDILGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLEAMQERQV 127
           FTP  +P+DI+G  ++ Q   EF+ + GPV  N LLADEINRAP K QSALLE MQER V
Sbjct: 106 FTPRPVPTDIIGTRIYRQGKEEFDTELGPVVVNFLLADEINRAPAKVQSALLEVMQERHV 165

Query: 128 TIEGNTYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPSKEEEKEILKR 185
           +I G T+ LP PF+V+ATQNPIE EG YPLPEAQ DRFL ++ VGYPS EEE+EI+ R
Sbjct: 166 SIGGKTFPLPNPFLVMATQNPIEHEGVYPLPEAQRDRFLFKINVGYPSPEEEREIIYR 223


>pir||S43189 hypothetical protein - Pseudomonas aeruginosa
           >gi|469101|emb|CAA46565.1| (X65613) ORF2 [Pseudomonas
           aeruginosa]
           Length = 263
           
 Score =  209 bits (527), Expect = 3e-53
 Identities = 101/173 (58%), Positives = 133/173 (76%)

Query: 11  LEEVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALGLEFRRVQFTP 70
           L+ V + ++GKD  ++L LA +LA GH+LIEDLPG+ KT ++ + A+ LGL F+R+QFT 
Sbjct: 9   LKAVDEILLGKDRQVRLALACLLARGHLLIEDLPGMGKTTLSHALARWLGLSFQRIQFTS 68

Query: 71  DLLPSDILGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLEAMQERQVTIE 130
           DLLP DILG +VF++ + +F F  GP+F  ++LADEINRA PK+QSALLEAM+E QVTIE
Sbjct: 69  DLLPGDILGTSVFDKDSGQFVFHPGPIFAELVLADEINRATPKSQSALLEAMEEGQVTIE 128

Query: 131 GNTYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPSKEEEKEIL 183
           G T  LP PF VIATQNP  Q GT+ LPE+QLDRFL+RL +GYP +  E+ +L
Sbjct: 129 GATRPLPEPFFVIATQNPASQGGTFSLPESQLDRFLMRLSLGYPGRAAERSLL 181


>gb|AAB91544.1| (AF017119) MoxR homolog [Allochromatium vinosum]
           Length = 191
           
 Score =  196 bits (493), Expect = 3e-49
 Identities = 93/160 (58%), Positives = 121/160 (75%)

Query: 12  EEVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALGLEFRRVQFTPD 71
           ++V +AI+G+  +++ +L ++LADGH+L+E  PGLAKT   K  A  L  +F R+QFTPD
Sbjct: 32  DQVGRAILGQHGLIERLLIALLADGHLLVEGAPGLAKTTAVKHLAAGLEGDFHRIQFTPD 91

Query: 72  LLPSDILGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLEAMQERQVTIEG 131
           LLP+D+ G  ++      F F +GP+F N+LLADE+NRAP K QSALLEAM ERQVT+  
Sbjct: 92  LLPADLTGTEIYRPHDGSFRFDRGPIFHNLLLADEVNRAPAKVQSALLEAMGERQVTVGR 151

Query: 132 NTYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRV 171
            TY LP  F+V+ATQNPIEQEGTYPLPEAQLDRFL+ +RV
Sbjct: 152 ETYPLPELFLVMATQNPIEQEGTYPLPEAQLDRFLLHVRV 191


>gb|AAB62561.1| (AF006054) MoxR [Mycobacterium tuberculosis]
           Length = 211
           
 Score =  193 bits (486), Expect = 2e-48
 Identities = 90/161 (55%), Positives = 122/161 (74%)

Query: 15  KKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALGLEFRRVQFTPDLLP 74
           ++ IVG+D +++ ML  +L+ GH+L+E +PG+AK+L  ++FA+ +G  F R+QFTPDL+P
Sbjct: 50  QRIIVGQDQLVERMLVGLLSKGHVLLEGVPGVAKSLAVETFARVVGGTFSRIQFTPDLVP 109

Query: 75  SDILGVNVFNQKTLEFEFKKGPVFTNILLADEINRAPPKTQSALLEAMQERQVTIEGNTY 134
           +DI+G  ++ Q   EF+ + GPV  N LLA EINRAP K QSALLE MQER V+I G T+
Sbjct: 110 TDIIGTRIYRQGREEFDTELGPVVANFLLAVEINRAPAKVQSALLEVMQERHVSIGGRTF 169

Query: 135 QLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPS 175
            +P PF+V+ATQNPIE EG YPLPEAQ DRFL ++ VG PS
Sbjct: 170 PMPSPFLVMATQNPIEHEGVYPLPEAQRDRFLFKINVGIPS 210


>dbj|BAA23276.1| (AB004097) ORF4 [Hyphomicrobium methylovorum]
           Length = 352
           
 Score =  146 bits (365), Expect = 3e-34
 Identities = 98/320 (30%), Positives = 169/320 (52%), Gaps = 31/320 (9%)

Query: 13  EVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALGLEFRRVQFTPDL 72
           EV +AIVG++  ++L++ ++ A GH+L+E   G+ KT + ++ A ALG  + RV+ T DL
Sbjct: 33  EVGRAIVGQERAIRLLVIAVFARGHVLLEGDVGVGKTTLLRAVAHALGGSYERVEGTIDL 92

Query: 73  LPSDILGVNVFNQKTLEFEFKKGPVF-----TNILLADEINRAPPKTQSALLEAMQERQV 127
           +PSD++     N+   +   + GPV       ++   +EINRA P+  S LL  M ER +
Sbjct: 93  MPSDMIYYTFLNEDG-KPRVEPGPVLRHGSDLSVFFFNEINRARPQVHSLLLRLMAERSI 151

Query: 128 TIEGNTYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPSKEEEKEILKRRI 187
           T     +  P   +V A +N IE+E T+ LP A  DRFL+ + +G P+ +E +  L    
Sbjct: 152 TAFNTEHFFPH-VLVFADRNRIEREETFELPAAARDRFLMEVSIGSPTDDESRRAL--LF 208

Query: 188 ERKMDDVE------INTVLSPEDILRMQREIE-EVYVSDAIIEYITSLVWATRED----- 235
           E +  DV+         V+    I  + + I+  V VS AI +Y   L  A R+      
Sbjct: 209 ETRFHDVDQLIGALKEGVIDYRQINALAKIIQSSVVVSPAIEKYTLDLWKAVRDPAAANV 268

Query: 236 -------KREIEVGVSPRGSLALLKLSRAYAAIEGRDYVIPDDVKAVAVPALSHRIILKR 288
                   R +  G SPRG   L++ +R  A + GR+ V+P+D++ +    ++HRI L  
Sbjct: 269 SIPGVDMTRLVAGGASPRGMSYLIRAARVSAWLAGREMVVPEDIRDIFYECMAHRIFLSP 328

Query: 289 ELWYMRIRQEDIIKKILEKV 308
                 +R+E++++ +++++
Sbjct: 329 ---VYELRREELVRSLIDQI 345


>sp|P30621|MOXR_METEX MOXR PROTEIN (MXAR PROTEIN) >gi|1771259|emb|CAA69191.1| (Y07864)
           mxaR [Methylobacterium extorquens]
           Length = 341
           
 Score =  143 bits (356), Expect = 3e-33
 Identities = 95/328 (28%), Positives = 171/328 (51%), Gaps = 27/328 (8%)

Query: 7   AQKVLEEVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALGLEFRRV 66
           A +   E+ KA+VG+D  ++L+  ++ A GH+++E   G+ KT + ++ A+ LG  + RV
Sbjct: 18  AARFEREIAKAVVGQDRAIRLLTIAIFARGHVMLEGDVGVGKTTLLRAVARGLGGAYERV 77

Query: 67  QFTPDLLPSDILGVNVFNQKTLEFEFKKGPVF-----TNILLADEINRAPPKTQSALLEA 121
           + T D++P+D++  + +  +      + GPV       ++   +EINRA P+  + LL  
Sbjct: 78  EGTVDMMPTDLI-YHTYLGEDGRPRVEPGPVLRRAEDLSVFFFNEINRARPQVHALLLRI 136

Query: 122 MQERQVTIEGNTYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPSKEEEKE 181
           M ER V+     Y+ P    V A +N +E+E T+ LP A  DRFL+ + +  P     ++
Sbjct: 137 MAERSVSAFNREYRFPN-LQVFADRNRVEREETFELPAAARDRFLMEIGMEAPRDAARRD 195

Query: 182 IL----KRRIERKMDDVEINTVLSPEDILRMQREIEEVYVSDAIIEYITSLVW------- 230
           ++        +R  ++VE   VL  E I  +   I+    ++  IE     +W       
Sbjct: 196 LVFDPRFHDTDRLTEEVEAG-VLDFERIGTIASAIQHAISAEPAIEAYVVGLWEALVRPA 254

Query: 231 -----ATREDKREIEVGVSPRGSLALLKLSRAYAAIEGRDYVIPDDVKAVAVPALSHRII 285
                A     R ++ G SPRG   L++ +R  A +EGRD+++P+D++AV    ++HR+ 
Sbjct: 255 PPHPLARHRMDRLVQGGASPRGVAFLVRAARVRAWLEGRDWLVPEDIRAVFPEVMAHRVF 314

Query: 286 LKRELWYMRIRQ--EDIIKKILEKVPVP 311
           L+  ++ MR  +   D+I+ + E VP P
Sbjct: 315 LE-PVYEMRRAEIVPDLIRAVFETVPAP 341


>sp|P29901|MOXR_PARDE MOXR PROTEIN >gi|94691|pir||D41377 methanol dehydrogenase
           regulatory protein moxR [validated] - Paracoccus
           denitrificans
           Length = 339
           
 Score =  127 bits (317), Expect = 1e-28
 Identities = 98/322 (30%), Positives = 160/322 (49%), Gaps = 35/322 (10%)

Query: 18  IVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKALGLEFRRVQFTPDLLPSDI 77
           ++G+   ++L+L S L  GH+L+    G  KT + ++ A+ALG  + RV+ T DLLP+D+
Sbjct: 23  VLGQARTIRLLLISALCRGHVLLAGDVGTGKTTLLRAMARALGGPYGRVEGTVDLLPTDL 82

Query: 78  LGVNVFNQKTLEFEFKKGPVFTN-----ILLADEINRAPPKTQSALLEAMQERQVTIEGN 132
           +  +    +      + GPV        +   +EINRA P+  + LL  M ER ++    
Sbjct: 83  I-YSTHIAEDGRPRIEPGPVLEQGEDMAVFFFNEINRARPQVHALLLRLMAERSLSAFRR 141

Query: 133 TYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPSKEEEKEILKRRIERKMD 192
            Y+ P    V A +N IE++ T+ LP A  DRFL+ + V  P+  E++  L    E +  
Sbjct: 142 EYRFPH-LQVFADRNQIERDETFELPAAARDRFLMEIAVDAPAAPEDRVALA--FEPRFH 198

Query: 193 DV-----EINTVLSPEDILR-MQREIEE-VYVSDAIIEYITSLVWATR------------ 233
           D      E+   + P   L  +   ++   + S A+  Y+  L  A R            
Sbjct: 199 DTTALIAEVGQGILPYRGLNGLAAGVQSGTHASPALRRYVFDLCEALRNPASAGLALEGA 258

Query: 234 EDKREIEVGVSPRGSLALLKLSRAYAAIEGRDYVIPDDVKAVAVPALSHRIILKRELWYM 293
           +  R I  GVSPRG   L++ +RA A +EGR+ V+P DV+AV  P ++HRI L       
Sbjct: 259 DAARLIRGGVSPRGMQHLVRAARACAWLEGREAVLPQDVRAVLAPVMAHRIFLSPA---Y 315

Query: 294 RIRQEDIIKKILE----KVPVP 311
             R+E ++  +++     +PVP
Sbjct: 316 EPRREALVPALIDAAFATIPVP 337


>pir||E69109 conserved hypothetical protein MTH1814 - Methanobacterium
           thermoautotrophicum (strain Delta H)
           >gi|2622947|gb|AAB86280.1| (AE000935) conserved protein
           [Methanobacterium thermoautotrophicum]
           Length = 298
           
 Score = 74.1 bits (179), Expect = 2e-12
 Identities = 64/226 (28%), Positives = 105/226 (46%), Gaps = 33/226 (14%)

Query: 1   MNVQVKAQKVLEEVKKA--IVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAKSFAKA 58
           MN   K  K+   ++    I  +D ++ L L+S L    +L+E  PG  KTL+AK  A+A
Sbjct: 1   MNTTEKLDKIDTSLRNVGYIPSRDIIITLFLSSELKKP-VLVEGPPGTGKTLLAKKTAEA 59

Query: 59  LGLEFRRVQFTPDLLPSDILGVNVFNQKTLEFE----------------FKKGPVFT--- 99
           LG EF R+Q    +    I+G   + ++ L  E                F K P+ +   
Sbjct: 60  LGREFFRIQCYEGITFEQIVGEWNYQKQLLSLEKSRIHGSDEDVFREDYFIKRPLLSAFI 119

Query: 100 ----NILLADEINRAPPKTQSALLEAMQERQVTIEG-NTYQLPRPFIVIATQNPIEQEGT 154
               ++LL DEI++A  + +S LL+A+ E+Q+T+    T+ L    +V  T N       
Sbjct: 120 NEKPSLLLIDEIDKADEEVESFLLQALGEKQITVNDLGTFDLRNDIMVFLTSNSQRN--- 176

Query: 155 YPLPEAQLDRFLVRLRVGYPSKEEEKEILKRRIERKMDDVEINTVL 200
             L +   DR L  + + YP  E E EI++  +    + +   TV+
Sbjct: 177 --LLDETRDRCLY-IHIDYPDPEREMEIVRAHVPSAPEGLIRETVM 219


>pir||C65178 hypothetical 57.4 kD protein in asnA-kup intergenic region -
           Escherichia coli (strain K-12)
           >gi|2367275|gb|AAC76769.1| (AE000451) putative
           2-component regulator [Escherichia coli K12]
           Length = 506
           
 Score = 69.1 bits (166), Expect = 6e-11
 Identities = 73/299 (24%), Positives = 132/299 (43%), Gaps = 34/299 (11%)

Query: 6   KAQKVLEEVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAK----SFAKALGL 61
           +  ++   ++K +  + + ++L L + L+   + +   PG+AK+L+A+    +F  A   
Sbjct: 18  RISRLSSSLEKGLYERSHAIRLCLLAALSGESVFLLGPPGIAKSLIARRLKFAFQNARAF 77

Query: 62  EFRRVQFTPDLLPSDILG---VNVFNQKTLEFEFKKGPV-FTNILLADEINRAPPKTQSA 117
           E+   +F+    P ++ G   +     +        G +    I+  DEI +A P   + 
Sbjct: 78  EYLMTRFST---PEEVFGPLSIQALKDEGRYERLTSGYLPEAEIVFLDEIWKAGPAILNT 134

Query: 118 LLEAMQERQVTIEGNTYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPSKE 177
           LL A+ ERQ     +  ++P   +V A+    E + +    EA  DR L+RL   +  K 
Sbjct: 135 LLTAINERQFRNGAHVEKIPMRLLVAASNELPEADSSL---EALYDRMLIRL---WLDKV 188

Query: 178 EEKEILKRRIERKMDD----VEINTVLSPEDILRMQREIEEVYVSDAIIEYITSLVWATR 233
           ++K   +  +  + D+    V     ++ E+  R Q+EI E+ + D + E I  L    +
Sbjct: 189 QDKANFRSMLTSQQDENDNPVPDALQVTDEEYERWQKEIGEITLPDHVFELIFML--RQQ 246

Query: 234 EDKREIEVGVSPRGSLALLKLSRAYAAIEGRDYVIPDDVKAVAVPALSHRIILKRELWY 292
            DK      VS R     ++L +A A   GR  V P D+           I+LK  LWY
Sbjct: 247 LDKLPDAPYVSDRRWKKAIRLLQASAFFSGRSAVAPVDL-----------ILLKDCLWY 294


>sp|P31473|YIEN_ECOLI HYPOTHETICAL 56.4 KD PROTEIN IN ASNA-KUP INTERGENIC REGION
           Length = 498
           
 Score = 69.1 bits (166), Expect = 6e-11
 Identities = 73/299 (24%), Positives = 132/299 (43%), Gaps = 34/299 (11%)

Query: 6   KAQKVLEEVKKAIVGKDNVLKLMLASMLADGHILIEDLPGLAKTLMAK----SFAKALGL 61
           +  ++   ++K +  + + ++L L + L+   + +   PG+AK+L+A+    +F  A   
Sbjct: 10  RISRLSSSLEKGLYERSHAIRLCLLAALSGESVFLLGPPGIAKSLIARRLKFAFQNARAF 69

Query: 62  EFRRVQFTPDLLPSDILG---VNVFNQKTLEFEFKKGPV-FTNILLADEINRAPPKTQSA 117
           E+   +F+    P ++ G   +     +        G +    I+  DEI +A P   + 
Sbjct: 70  EYLMTRFST---PEEVFGPLSIQALKDEGRYERLTSGYLPEAEIVFLDEIWKAGPAILNT 126

Query: 118 LLEAMQERQVTIEGNTYQLPRPFIVIATQNPIEQEGTYPLPEAQLDRFLVRLRVGYPSKE 177
           LL A+ ERQ     +  ++P   +V A+    E + +    EA  DR L+RL   +  K 
Sbjct: 127 LLTAINERQFRNGAHVEKIPMRLLVAASNELPEADSSL---EALYDRMLIRL---WLDKV 180

Query: 178 EEKEILKRRIERKMDD----VEINTVLSPEDILRMQREIEEVYVSDAIIEYITSLVWATR 233
           ++K   +  +  + D+    V     ++ E+  R Q+EI E+ + D + E I  L    +
Sbjct: 181 QDKANFRSMLTSQQDENDNPVPDALQVTDEEYERWQKEIGEITLPDHVFELIFML--RQQ 238

Query: 234 EDKREIEVGVSPRGSLALLKLSRAYAAIEGRDYVIPDDVKAVAVPALSHRIILKRELWY 292
            DK      VS R     ++L +A A   GR  V P D+           I+LK  LWY
Sbjct: 239 LDKLPDAPYVSDRRWKKAIRLLQASAFFSGRSAVAPVDL-----------ILLKDCLWY 286


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.319    0.138    0.378 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 108466597
Number of Sequences: 2977
Number of extensions: 4529929
Number of successful extensions: 13920
Number of sequences better than 1.0e-10: 44
Number of HSP's better than  0.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 13810
Number of HSP's gapped (non-prelim): 45
length of query: 314
length of database: 189,106,746
effective HSP length: 59
effective length of query: 255
effective length of database: 153,796,013
effective search space: 39217983315
effective search space used: 39217983315
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 165 (68.7 bits)