BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB0854 (PAB0854) DE:Hypothetical protein
         (457 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||D75038 hypothetical protein PAB0854 - Pyrococcus abyssi (st...   901  0.0
pir||G71124 hypothetical protein PH0766 - Pyrococcus horikoshii ...   866  0.0
pir||T48661 acetate--CoA ligase (ADP-forming) (EC 6.2.1.13) alph...   402  e-111
pir||D75106 hypothetical protein PAB1937 - Pyrococcus abyssi (st...   395  e-109
pir||A71028 hypothetical protein PH1517 - Pyrococcus horikoshii ...   392  e-108
pir||E71189 hypothetical protein PH1789 - Pyrococcus horikoshii ...   388  e-107
pir||E75149 succinyl-coa synthetase alpha chain related protein ...   383  e-105
sp|Q58010|Y590_METJA HYPOTHETICAL PROTEIN MJ0590 >gi|2128020|pir...   383  e-105
pir||A75021 succinyl-coa synthetase alpha chain related protein ...   382  e-105
pir||H71207 hypothetical protein PH1928 - Pyrococcus horikoshii ...   375  e-103
gi|11498810 conserved hypothetical protein [Archaeoglobus fulgid...   369  e-101
pir||F75054 hypothetical protein PAB1431 - Pyrococcus abyssi (st...   365  e-100
pir||H71106 hypothetical protein PH0625 - Pyrococcus horikoshii ...   354  8e-97
gi|11499106 conserved hypothetical protein [Archaeoglobus fulgid...   353  2e-96
emb|CAC12278.1| (AL445066) probable acetyl-CoA synthetase [Therm...   339  5e-92
gb|AAF88064.1|AF286346_1 (AF286346) acetyl-CoA synthetase [Entam...   327  2e-88
gb|AAK42002.1| Conserved hypothetical protein [Sulfolobus solfat...   323  3e-87
gb|AAD44021.1|AF107206_1 (AF107206) acetyl-CoA synthetase [Giard...   309  3e-83
gi|11498792 conserved hypothetical protein [Archaeoglobus fulgid...   301  1e-80
pir||T35770 hypothetical protein SC8A6.03c SC8A6.03c - Streptomy...   295  7e-79
gi|11499522 conserved hypothetical protein [Archaeoglobus fulgid...   279  5e-74
gi|11498537 conserved hypothetical protein [Archaeoglobus fulgid...   279  5e-74
pir||C82443 conserved hypothetical protein VCA0574 [imported] - ...   261  1e-68
dbj|BAA10925.1| (D64044) hypothetycal 67KD protein fragment in U...   234  2e-60
sp|P76594|YFIQ_ECOLI HYPOTHETICAL 98.0 KD PROTEIN IN UNG-PSSA IN...   234  2e-60
emb|CAA10043.1| (AJ012480) pimeloyl-CoA synthetase [Pseudomonas ...   199  5e-50
pir||B83518 pimeloyl-CoA synthetase PA1017 [imported] - Pseudomo...   197  2e-49
pir||T35878 hypothetical protein SC9B10.09 - Streptomyces coelic...   193  3e-48
gb|AAG19369.1| (AE005031) acetyl-CoA synthetase; Acs3 [Halobacte...   189  6e-47
pir||H83024 hypothetical protein PA4978 [imported] - Pseudomonas...   159  6e-38
pir||A72707 probable succinyl-CoA synthetase alpha chain APE1072...    89  1e-16
gi|11499767 succinyl-CoA synthetase, alpha subunit (sucD-2) [Arc...    85  2e-15
sp|Q58643|SUCD_METJA SUCCINYL-COA SYNTHETASE ALPHA CHAIN (SCS-AL...    82  1e-14
gb|AAK42618.1| Succinyl-CoA synthetase, alpha subunit (sucD) [Su...    82  1e-14
gb|AAA27504.2| (M35832) succinyl-CoA synthetase alpha-subunit [T...    79  1e-13
gi|11499134 succinyl-CoA synthetase, alpha subunit (sucD-1) [Arc...    78  3e-13
pir||F81399 succinate--CoA ligase (ADP-forming) (EC 6.2.1.5) alp...    78  3e-13
emb|CAB92672.1| (AL356832) succinyl CoA synthetase alpha chain [...    75  2e-12
sp|P09143|SUCD_THEFL SUCCINYL-COA SYNTHETASE ALPHA CHAIN (SCS-AL...    75  2e-12
prf||1708208A succinyl CoA synthetase [Thermus aquaticus]              75  2e-12
prf||1414360A succinyl-CoA synthetase alpha [Thermus aquaticus]        73  5e-12
pir||F81180 conserved hypothetical protein NMB0593 [imported] - ...    72  1e-11
pir||D81924 hypothetical protein NMA0796 [imported] - Neisseria ...    70  4e-11
emb|CAC12452.1| (AL445067) probable succinyl-CoA synthetase, alp...    70  6e-11

>pir||D75038 hypothetical protein PAB0854 - Pyrococcus abyssi (strain Orsay)
           >gi|5458714|emb|CAB50201.1| (AJ248287) hypothetical
           protein [Pyrococcus abyssi]
           Length = 457
           
 Score =  901 bits (2304), Expect = 0.0
 Identities = 457/457 (100%), Positives = 457/457 (100%)

Query: 1   MLDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYKGGNVYPVNVREEEVQGVKAYKSVKD 60
           MLDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYKGGNVYPVNVREEEVQGVKAYKSVKD
Sbjct: 1   MLDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYKGGNVYPVNVREEEVQGVKAYKSVKD 60

Query: 61  IPGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRY 120
           IPGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRY
Sbjct: 61  IPGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRY 120

Query: 121 GMRIIGPNCVGIMNTHADLNATFITVAKKGNVAFISQSGALGAGIVYKTIKEDIGFSKFI 180
           GMRIIGPNCVGIMNTHADLNATFITVAKKGNVAFISQSGALGAGIVYKTIKEDIGFSKFI
Sbjct: 121 GMRIIGPNCVGIMNTHADLNATFITVAKKGNVAFISQSGALGAGIVYKTIKEDIGFSKFI 180

Query: 181 SVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKAGKS 240
           SVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKAGKS
Sbjct: 181 SVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKAGKS 240

Query: 241 ESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQPLPRGKRVAIMT 300
           ESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQPLPRGKRVAIMT
Sbjct: 241 ESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQPLPRGKRVAIMT 300

Query: 301 NAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARGEDYYRTA 360
           NAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARGEDYYRTA
Sbjct: 301 NAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARGEDYYRTA 360

Query: 361 KLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPVLAMFMAGYVSEKAK 420
           KLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPVLAMFMAGYVSEKAK
Sbjct: 361 KLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPVLAMFMAGYVSEKAK 420

Query: 421 ELLEKNGIPTYERPEDVASAAYALVEQAKNVGVLEVE 457
           ELLEKNGIPTYERPEDVASAAYALVEQAKNVGVLEVE
Sbjct: 421 ELLEKNGIPTYERPEDVASAAYALVEQAKNVGVLEVE 457


>pir||G71124 hypothetical protein PH0766 - Pyrococcus horikoshii
           >gi|3257174|dbj|BAA29857.1| (AP000003) 457aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 457
           
 Score =  866 bits (2213), Expect = 0.0
 Identities = 433/457 (94%), Positives = 449/457 (97%)

Query: 1   MLDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYKGGNVYPVNVREEEVQGVKAYKSVKD 60
           MLDYFFNPKGIAVIGASNDPKKLGYEVFKNLK+YK G VYPVN++EEEVQGVKAYKSVKD
Sbjct: 1   MLDYFFNPKGIAVIGASNDPKKLGYEVFKNLKEYKKGKVYPVNIKEEEVQGVKAYKSVKD 60

Query: 61  IPGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRY 120
           IP E+DLAIIVVPK+FVKDTLIQCGEKGVKGVVIITAGFGETGEEGK+EEKELVEIAH+Y
Sbjct: 61  IPDEIDLAIIVVPKRFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKREEKELVEIAHKY 120

Query: 121 GMRIIGPNCVGIMNTHADLNATFITVAKKGNVAFISQSGALGAGIVYKTIKEDIGFSKFI 180
           GMRIIGPNCVGIMNTH DLNATFITVAKKGNVAFISQSGALGAGIVYKTIKEDIGFSKFI
Sbjct: 121 GMRIIGPNCVGIMNTHVDLNATFITVAKKGNVAFISQSGALGAGIVYKTIKEDIGFSKFI 180

Query: 181 SVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKAGKS 240
           SVGNMAD+DFAELMEYLADTEEDKAIALYIEG+RNG+KF+EVAKRVTKKKP+IALKAGKS
Sbjct: 181 SVGNMADVDFAELMEYLADTEEDKAIALYIEGVRNGKKFMEVAKRVTKKKPIIALKAGKS 240

Query: 241 ESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQPLPRGKRVAIMT 300
           ESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAF+QPLPRG +VAIMT
Sbjct: 241 ESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFSQPLPRGNKVAIMT 300

Query: 301 NAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARGEDYYRTA 360
           NAGGPGVLTADELDKRGLKLA LEEKTIEELRSFLPPMAAVKNPVDMIASARGEDYYRTA
Sbjct: 301 NAGGPGVLTADELDKRGLKLATLEEKTIEELRSFLPPMAAVKNPVDMIASARGEDYYRTA 360

Query: 361 KLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPVLAMFMAGYVSEKAK 420
           KLLLQDPNVDMLIAICVVPTFAGMT TEHAEGIIRA+KEVNN KPVLAMFMAGYVSEKAK
Sbjct: 361 KLLLQDPNVDMLIAICVVPTFAGMTLTEHAEGIIRAVKEVNNEKPVLAMFMAGYVSEKAK 420

Query: 421 ELLEKNGIPTYERPEDVASAAYALVEQAKNVGVLEVE 457
           ELLEKNGIPTYERPEDVASAAYALVEQAKNVG+LEVE
Sbjct: 421 ELLEKNGIPTYERPEDVASAAYALVEQAKNVGILEVE 457


>pir||T48661 acetate--CoA ligase (ADP-forming) (EC 6.2.1.13) alpha chain
           [validated] - Pyrococcus furiosus
           >gi|5419966|emb|CAB46516.1| (AJ240061) acetyl-CoA
           synthetase [Pyrococcus furiosus]
           Length = 462
           
 Score =  402 bits (1022), Expect = e-111
 Identities = 228/456 (50%), Positives = 300/456 (65%), Gaps = 12/456 (2%)

Query: 2   LDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYK-GGNVYPVNVR--EEEVQG--VKAYK 56
           L+  FNPK +AVIGAS  P K+GY + KNL +Y   G +YPVN++  E E+ G   K YK
Sbjct: 3   LEALFNPKSVAVIGASAKPGKIGYAIMKNLIEYGYEGKIYPVNIKGGEIEINGRKFKVYK 62

Query: 57  SVKDIPGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEI 116
           SV +IP EVD+A+IVVP KFV   L +CG+KGVK V II++GFGE GEEGKK E++LVE 
Sbjct: 63  SVLEIPDEVDMAVIVVPAKFVPQVLEECGQKGVKVVPIISSGFGELGEEGKKVEQQLVET 122

Query: 117 AHRYGMRIIGPNCVGIMNTHADLNATF-ITVAKKGNVAFISQSGALGAGIVYKTIKEDIG 175
           A +YGMRI+GPN  G++ T A LNATF  T    G +A ISQSGALG  ++  TI E IG
Sbjct: 123 ARKYGMRILGPNIFGVVYTPAKLNATFGPTDVLPGPLALISQSGALGIALMGWTILEKIG 182

Query: 176 FSKFISVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIAL 235
            S  +SVGN AD+D A+L+E+  D E  +AI +Y+EG+++GR+F+EVAK V+KKKP+I +
Sbjct: 183 LSAVVSVGNKADIDDADLLEFFKDDENTRAILIYMEGVKDGRRFMEVAKEVSKKKPIIVI 242

Query: 236 KAGKSESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQ-PLPRGK 294
           KAG+SE GA+AA+SHTGSLAGS K+Y AAFKQSGVL A TI E    ARA +  P P+G 
Sbjct: 243 KAGRSERGAKAAASHTGSLAGSDKVYSAAFKQSGVLRAYTIGEAFDWARALSNLPEPQGD 302

Query: 295 RVAIMTNAGGPGVLTADELDKRGLKL-ANLEEKTIEELRSFLPPMAAVKNPVDMIASARG 353
            V I+TN GG GV+  D  ++ GL L  NLEE  I    + +PP  + KNPVD+   A G
Sbjct: 303 NVVIITNGGGIGVMATDAAEEEGLHLYDNLEELKI--FANHMPPFGSYKNPVDLTGMADG 360

Query: 354 EDYYRTAKLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPVLAMFMAG 413
           + Y    +  L  P +   IA+    T A + P E AE +IR   E    KP++   + G
Sbjct: 361 KSYEGAIRDALAHPEMHS-IAVLYCQT-AVLDPRELAEIVIREYNESGRKKPLVVAIVGG 418

Query: 414 YVSEKAKELLEKNGIPTYERPEDVASAAYALVEQAK 449
             +++A ++L +NGIP Y  PE    A  AL + +K
Sbjct: 419 IEAKEAIDMLNENGIPAYPEPERAIKALSALYKWSK 454


>pir||D75106 hypothetical protein PAB1937 - Pyrococcus abyssi (strain Orsay)
           >gi|5458076|emb|CAB49565.1| (AJ248285) hypothetical
           protein [Pyrococcus abyssi]
           Length = 460
           
 Score =  395 bits (1005), Expect = e-109
 Identities = 222/458 (48%), Positives = 297/458 (64%), Gaps = 16/458 (3%)

Query: 2   LDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYK-GGNVYPVNVR--EEEVQG--VKAYK 56
           L+  FNPK IAVIGAS+ P K+GY + KNL +Y   G +YPVN++  E E+ G   K YK
Sbjct: 3   LEALFNPKSIAVIGASSKPGKIGYAIMKNLIEYGYEGKIYPVNIKGGEMEISGRKFKVYK 62

Query: 57  SVKDIPGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEI 116
           S+ ++P EVD+AIIVVP KFV   + +CG+KGVK V II++GFGE GEEGKK E++LVE 
Sbjct: 63  SILEVPDEVDMAIIVVPAKFVPQVVEECGQKGVKVVPIISSGFGELGEEGKKVEQQLVET 122

Query: 117 AHRYGMRIIGPNCVGIMNTHADLNATF-ITVAKKGNVAFISQSGALGAGIVYKTIKEDIG 175
           A +YGMRI+GPN  G++ T A LN TF  T    G +A ISQSGALG  ++  TI E IG
Sbjct: 123 ARKYGMRILGPNIFGVVYTPAKLNGTFGPTDVLPGPLALISQSGALGIALMGWTILEKIG 182

Query: 176 FSKFISVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIAL 235
            S  +SVGN AD+D A+L+E+  D E  +AI +Y+EG+++GR+F+EVAK V+KKKP+I +
Sbjct: 183 LSAVVSVGNKADIDDADLLEFFKDDENTRAILIYMEGVKDGRRFMEVAKEVSKKKPIIVI 242

Query: 236 KAGKSESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQ-PLPRGK 294
           KAG+SE GA+AA+SHTGSLAGS  IY AAFKQSGVL A TI E    ARA +  P P+G 
Sbjct: 243 KAGRSERGAKAAASHTGSLAGSDTIYSAAFKQSGVLRALTIGEAFDWARALSNLPEPQGD 302

Query: 295 RVAIMTNAGGPGVLTADELDKRGLKLANLEEKTIEELRSF---LPPMAAVKNPVDMIASA 351
            V I+TN GG GV+  D  ++ GLKL +     +E+L+ F   +PP  + KNPVD+   A
Sbjct: 303 NVVIITNGGGIGVMATDAAEEEGLKLYD----DLEQLKIFANHMPPFGSYKNPVDLTGMA 358

Query: 352 RGEDYYRTAKLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPVLAMFM 411
             + Y    +  L  P +  +I +      A + P + AE IIR   E    KP++   +
Sbjct: 359 DAKSYEGAIRDALNHPEMHSIIVLYC--QTAVLDPRDLAEIIIREYNESGRKKPLVVAIV 416

Query: 412 AGYVSEKAKELLEKNGIPTYERPEDVASAAYALVEQAK 449
            G  +++A + L +NGIP Y  PE    A  AL   +K
Sbjct: 417 GGIEAKEAIDTLNENGIPAYPEPERAVKALSALYRWSK 454


>pir||A71028 hypothetical protein PH1517 - Pyrococcus horikoshii
           >gi|3257942|dbj|BAA30625.1| (AP000006) 460aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 460
           
 Score =  392 bits (997), Expect = e-108
 Identities = 221/458 (48%), Positives = 299/458 (65%), Gaps = 16/458 (3%)

Query: 2   LDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYK-GGNVYPVNVR--EEEVQG--VKAYK 56
           L+  FNPK IAVIGAS+ P K+GY + KNL +Y   G +YPVN++  E E+ G   K YK
Sbjct: 3   LEALFNPKSIAVIGASSKPGKIGYAIMKNLIEYGYEGKIYPVNIKGGEMEISGRKFKVYK 62

Query: 57  SVKDIPGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEI 116
           S+ ++P EVD+A+IVVP K V + + +CG+KGVK   II++GFGE GEEGKK E++LVE 
Sbjct: 63  SILEVPDEVDMAVIVVPAKSVPEVVEECGKKGVKVAPIISSGFGELGEEGKKVEQQLVET 122

Query: 117 AHRYGMRIIGPNCVGIMNTHADLNATF-ITVAKKGNVAFISQSGALGAGIVYKTIKEDIG 175
           A +YGMRI+GPN  G++ T A LNATF  T    G +A ISQSGALG  ++  TI E IG
Sbjct: 123 ARKYGMRILGPNIFGVVYTPAKLNATFGPTDVLPGPLALISQSGALGIALMGWTILEKIG 182

Query: 176 FSKFISVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIAL 235
            S  +SVGN AD+D A+L+E+  D E  KAI +Y+EG+++GR+F+EVAK V+KKKP+I +
Sbjct: 183 LSAVVSVGNKADIDDADLLEFFKDDENTKAILIYMEGVKDGRRFMEVAKEVSKKKPIIVI 242

Query: 236 KAGKSESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQ-PLPRGK 294
           KAG+SE GA+AA+SHTGSLAGS  IY AAFKQ+GVL A TI E    ARA +  P P+G+
Sbjct: 243 KAGRSERGAKAAASHTGSLAGSDTIYSAAFKQTGVLRALTIGEAFDWARALSNLPEPQGE 302

Query: 295 RVAIMTNAGGPGVLTADELDKRGLKLANLEEKTIEELRSF---LPPMAAVKNPVDMIASA 351
            V I+TN GG GV+  D  ++ GL L +     +E+L+ F   +PP  + KNPVD+   A
Sbjct: 303 NVVIITNGGGIGVMATDAAEEEGLHLYD----DLEQLKIFANHMPPFGSYKNPVDLTGMA 358

Query: 352 RGEDYYRTAKLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPVLAMFM 411
             + Y    +  L  P  DM   I +    A + P E A+ IIR   E    KP++   +
Sbjct: 359 DAKSYEGAIRDALAHP--DMHSIIVLYCQTAVLDPRELADVIIREYNESGRKKPLVVAIV 416

Query: 412 AGYVSEKAKELLEKNGIPTYERPEDVASAAYALVEQAK 449
            G  +++A ++L +NGIP Y  PE    A  AL + +K
Sbjct: 417 GGIEAKQAIDVLNENGIPAYPEPERAVKALSALYKWSK 454


>pir||E71189 hypothetical protein PH1789 - Pyrococcus horikoshii
           >gi|3258225|dbj|BAA30908.1| (AP000007) 472aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 472
           
 Score =  388 bits (985), Expect = e-107
 Identities = 203/460 (44%), Positives = 287/460 (62%), Gaps = 18/460 (3%)

Query: 5   FFNPKGIAVIGASNDPKKLGYEVFKNLKQYKG-----GNVYPVNVREEEVQGVKAYKSVK 59
           FF PK +A+IGA+N   K+G  +F+N K+ K      GN+YPVN + +E++G K Y  V 
Sbjct: 13  FFEPKAVAIIGATNKKGKVGNVIFENFKKNKEKGIFKGNIYPVNPKLDEIEGYKVYHDVS 72

Query: 60  DIPGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHR 119
           ++P + DLA+I +P   V +T+ + GEKG+K V+IIT GFGE GEEGK+ E+E++EIA  
Sbjct: 73  ELPDDTDLAVIAIPAPAVPETMRKIGEKGIKSVIIITGGFGELGEEGKRMEQEILEIARA 132

Query: 120 YGMRIIGPNCVGIMNTHADLNATFITVAK-----KGNVAFISQSGALGAGIVYKTIKEDI 174
            G+R+IGPNCVG+      ++  F+   K      G +AFISQSGA  A ++       I
Sbjct: 133 NGIRVIGPNCVGVYVPDTGVDTVFLPDEKMDRPPSGPIAFISQSGAFAAAMLDWAAMAGI 192

Query: 175 GFSKFISVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIA 234
           G  K +S GN  D+D A+LMEY A  +E K +  YIEG+++GRKF+E AKRVTK KP+IA
Sbjct: 193 GIGKMVSYGNKIDVDDADLMEYFAHDDEIKVMTFYIEGVKDGRKFMETAKRVTKIKPIIA 252

Query: 235 LKAGKSESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQ-PLPRG 293
           LK+G++E GA+AASSHTGSLAG   IY+A FKQ+G++ A   + M  +A+AF +  LP+G
Sbjct: 253 LKSGRTEYGAKAASSHTGSLAGQDVIYDAVFKQTGIIRAEDFEHMFDLAKAFAKCKLPKG 312

Query: 294 KRVAIMTNAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARG 353
            R+ I+T+ GG GV+ +D + K GLKLA L E+TI+ LR   PP A V NP D++     
Sbjct: 313 DRIGIITDGGGAGVMASDAVAKFGLKLAELSEETIKFLRERFPPHAVVGNPTDVVGDTDA 372

Query: 354 EDYYRTAKLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEV--NNGKPVLAMFM 411
           E Y    +   +DPNVD ++ I +        P    E +I  I +    + KP++ + M
Sbjct: 373 ERYRLALEAFTKDPNVDAILLIVLF-----QVPLLDEEEVINIITDYAKKSDKPIVVVSM 427

Query: 412 AGYVSEKAKELLEKNGIPTYERPEDVASAAYALVEQAKNV 451
            GY ++K   +LE+ GIP Y  PE    A   LV  AK +
Sbjct: 428 GGYKTDKYARMLEERGIPVYPTPERGVRALAGLVRYAKYI 467


>pir||E75149 succinyl-coa synthetase alpha chain related protein PAB2112 -
           Pyrococcus abyssi (strain Orsay)
           >gi|5457786|emb|CAB49276.1| (AJ248284) SUCCINYL-COA
           SYNTHETASE ALPHA CHAIN related protein [Pyrococcus
           abyssi]
           Length = 472
           
 Score =  383 bits (973), Expect = e-105
 Identities = 200/460 (43%), Positives = 287/460 (61%), Gaps = 18/460 (3%)

Query: 5   FFNPKGIAVIGASNDPKKLGYEVFKNLKQYKG-----GNVYPVNVREEEVQGVKAYKSVK 59
           FF P+ +A+IGA+N   K+G  +F+N K+ K      GN+YPVN + +E+ G K Y  V 
Sbjct: 13  FFEPRAVAIIGATNKKGKVGNVIFENFKRNKEKGIFKGNIYPVNPKLDEIDGYKVYHDVS 72

Query: 60  DIPGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHR 119
           ++P + DLA+I +P   V +T+ +  EKG+K V+IIT GFGE GEEGK+ E+E++EIA  
Sbjct: 73  ELPDDTDLAVIAIPAPAVPETMKKIAEKGIKAVIIITGGFGELGEEGKRMEQEILEIARA 132

Query: 120 YGMRIIGPNCVGIMNTHADLNATFITVAK-----KGNVAFISQSGALGAGIVYKTIKEDI 174
            G+R+IGPNCVG+      ++  F+   K      G +AFISQSGA  A ++       I
Sbjct: 133 NGIRVIGPNCVGVYAPDTGVDTVFLPEEKMDRPKSGPIAFISQSGAFAAAMLDWAAMAGI 192

Query: 175 GFSKFISVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIA 234
           G  K +S GN  D+D A+LMEY A  +E K +  YIEG+++GRKF+E AKRVTK KP+IA
Sbjct: 193 GIGKMVSYGNKIDVDDADLMEYFAQDDEIKVMTFYIEGVKDGRKFMETAKRVTKIKPIIA 252

Query: 235 LKAGKSESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQ-PLPRG 293
           LK+G++E GA+AASSHTGSLAG   IY+A FKQ+G++ A   + M  +A+AF +  LP+G
Sbjct: 253 LKSGRTEYGAKAASSHTGSLAGQDVIYDAVFKQTGIIRAEDFEHMFDLAKAFAKCKLPKG 312

Query: 294 KRVAIMTNAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARG 353
            R+ I+T+ GG GV+ +D + K GLKLA L E+TI+ L+   PP A V NP D++     
Sbjct: 313 DRIGIITDGGGAGVMASDAVAKFGLKLAELSEETIKFLKERFPPHAVVGNPTDVVGDTDA 372

Query: 354 EDYYRTAKLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEV--NNGKPVLAMFM 411
           E Y    +  ++DPNVD ++ I +        P    + +I  I +    + KP++ + M
Sbjct: 373 ERYRLALEAFIKDPNVDAILLIVLF-----QVPLLDEKEVIDIITDYAKKSDKPIVVVSM 427

Query: 412 AGYVSEKAKELLEKNGIPTYERPEDVASAAYALVEQAKNV 451
            GY ++K  ++LE+ GIP Y  PE    A   LV  AK V
Sbjct: 428 GGYKTDKYAKMLEERGIPVYPTPERGVRALAGLVRYAKYV 467


>sp|Q58010|Y590_METJA HYPOTHETICAL PROTEIN MJ0590 >gi|2128020|pir||F64373 hypothetical
           protein homolog MJ0590 - Methanococcus jannaschii
           >gi|1591298|gb|AAB98580.1| (U67507) conserved
           hypothetical protein [Methanococcus jannaschii]
           Length = 704
           
 Score =  383 bits (973), Expect = e-105
 Identities = 212/445 (47%), Positives = 294/445 (65%), Gaps = 14/445 (3%)

Query: 2   LDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYKGGNVYPVNVREEEVQGVKAYKSVKDI 61
           L Y   PK +A+IGAS    K+GY + KNLK + G  +YP+N + +E+ G+K YKSV D+
Sbjct: 8   LKYISYPKSVAIIGASKTEGKVGYAIMKNLKDFNG-KIYPINPKYDEIFGIKCYKSVLDV 66

Query: 62  PGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRYG 121
             ++DLA+IVVP   V   L +CG+KGVKG VIITAGF E G    + E ++ EIA RY 
Sbjct: 67  EDDIDLAVIVVPNIVVPKVLEECGKKGVKGAVIITAGFSEVGNY--ELENKIKEIAKRYN 124

Query: 122 MRIIGPNCVGIMNTHADLNATFITV-AKKGNVAFISQSGALGAGIVYKTIKEDIGFSKFI 180
           +RIIGPNC+GIMNTH +LNATF  V   KG V+ ISQSGA+   I+      +IGFSK +
Sbjct: 125 IRIIGPNCLGIMNTHINLNATFAKVFPPKGGVSIISQSGAVLNAILDIAPLLNIGFSKVV 184

Query: 181 SVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKAGKS 240
           S+GN AD+  ++L+EY  D E+ K + LYIEG+++ ++F++VAK+++KKKP+IALK+G++
Sbjct: 185 SIGNKADIQESDLLEYFLDDEDTKIVVLYIEGLKD-KRFLKVAKKLSKKKPIIALKSGRT 243

Query: 241 ESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAF-TQPLPRGKRVAIM 299
           E G +AA SHTGSLAG   IYEAAFK++G++ A T +E++ +   F TQP      + I+
Sbjct: 244 EVGKKAAKSHTGSLAGEDVIYEAAFKEAGIIRAYTFEELVDLIHLFSTQPTISSNEIGII 303

Query: 300 TNAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARGEDYYRT 359
           TNAGG GVL AD      +KL+N E+ TIE+L++ LPP A + NP+D+I  A  E Y + 
Sbjct: 304 TNAGGFGVLAADSCVDYNMKLSNFEKSTIEKLKNILPPTANISNPLDIIGDATPERYKKV 363

Query: 360 AKLLLQDPNVDMLIAICVVPTFAGMT-PTEHAEGII---RAIKEVNNGKPVLAMFMAGYV 415
            ++L +D NV  L+   V+ T   MT P E A+ II    + KE  N KP++  F+ G  
Sbjct: 364 IEVLAEDSNVKGLL---VILTPQEMTKPLEVAKSIIEVKNSHKEFKN-KPLITSFVGGVS 419

Query: 416 SEKAKELLEKNGIPTYERPEDVASA 440
            + AK  L KNGIP Y  PE+   A
Sbjct: 420 VKGAKSYLRKNGIPAYITPENGVKA 444


>pir||A75021 succinyl-coa synthetase alpha chain related protein PAB1230 -
           Pyrococcus abyssi (strain Orsay)
           >gi|5459121|emb|CAB50607.1| (AJ248288) SUCCINYL-COA
           SYNTHETASE ALPHA SUBUNIT RELATED PROTEIN [Pyrococcus
           abyssi]
           Length = 466
           
 Score =  382 bits (970), Expect = e-105
 Identities = 214/468 (45%), Positives = 296/468 (62%), Gaps = 22/468 (4%)

Query: 2   LDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYKGGNVYPVNVR--EEEVQG--VKAYKS 57
           LD+ F P+ +AVIGAS+ P K+G  + ++L     G +Y VNV+  E EV G   K Y+S
Sbjct: 6   LDFLFYPRSVAVIGASHVPGKVGNAILRSLVNGFNGKIYAVNVKGGEIEVNGKKFKVYRS 65

Query: 58  VKDIPGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIA 117
           VK+IP EVD+A+I VP KFV D + +CGEKGVKGVV+I+AGF E G    +EE  LV+ A
Sbjct: 66  VKEIPDEVDVAVIAVPAKFVPDVIDECGEKGVKGVVVISAGFKEAGRADLEEE--LVKRA 123

Query: 118 HRYGMRIIGPNCVGIMNTHADLNATFITVAKK-----GNVAFISQSGALGAGIVYKTIKE 172
            ++G+R++GPNC+G+ N     +  F    ++     G +AF+SQSGA GA I+    + 
Sbjct: 124 RKWGIRVVGPNCLGVTNIENGFDCNFNPPERQARPKFGPIAFMSQSGAFGAAILDWAARH 183

Query: 173 DIGFSKFISVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPV 232
           ++G SKFIS+GNMADLD ++ M YL D  + K I  YIEG+++GRKF   AK  TK KPV
Sbjct: 184 EVGMSKFISLGNMADLDESDFMLYLKDDPKTKVITAYIEGVKDGRKFFNAAKETTKVKPV 243

Query: 233 IALKAGKSESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQPLP- 291
           I LKAG++E+GA+AA+SHTGSLAGS+KIYEAAFKQSGVL+A ++ ++ + A+A     P 
Sbjct: 244 IILKAGRTEAGAKAAASHTGSLAGSYKIYEAAFKQSGVLMAKSMRQLFNYAKALAMQNPA 303

Query: 292 RGKRVAIMTNAGGPGVLTADELDKRGLKLANLEEKTIEELRSF-----LPPMAAVKNPVD 346
           +G RVAI+TN GG GV+ +D L + GLKLA   E+T E+ R       LP   + +NPVD
Sbjct: 304 KGDRVAIVTNGGGAGVMMSDGLLEHGLKLAEFTEETKEKFRKAIEEGKLPEHMSYRNPVD 363

Query: 347 MIASARGEDYYRTAKLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPV 406
           +I  A    Y    + +L+DPNVD+++   V+  F      E    ++  +KE   GKP+
Sbjct: 364 VIGDAPSSRYEVAIRYVLEDPNVDIVV---VIALFQSPALDEGIVDVMGRVKEY--GKPI 418

Query: 407 LAMFMAGYVSEKAKELLEKNGIPTYERPEDVASAAYALVEQAKNVGVL 454
           + +   G   E     +EK GIP +E  ED   A YALV   K +  L
Sbjct: 419 VFVAPGGEFPEAMARRIEKVGIPVFETVEDGVDAVYALVSYGKYLSEL 466


>pir||H71207 hypothetical protein PH1928 - Pyrococcus horikoshii
           >gi|3258372|dbj|BAA31055.1| (AP000007) 466aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 466
           
 Score =  375 bits (952), Expect = e-103
 Identities = 209/469 (44%), Positives = 296/469 (62%), Gaps = 24/469 (5%)

Query: 2   LDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYKGGNVYPVNVR--EEEVQG--VKAYKS 57
           LD+ F P+ +AVIGAS+ P K+G  + ++L     G +Y VNV+  E EV G   K YKS
Sbjct: 6   LDFLFYPESVAVIGASHVPGKVGNGILRSLVNNFRGKIYAVNVKGGEIEVNGKKFKVYKS 65

Query: 58  VKDIPGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIA 117
           +KD+P +VD+A+I VP KFV + + +CGEKGVKGVV+I+AGF E G    +EE  LV+ A
Sbjct: 66  IKDVPDKVDVAVIAVPAKFVPEVIDECGEKGVKGVVVISAGFKEAGRADLEEE--LVKRA 123

Query: 118 HRYGMRIIGPNCVGIMNTHADLNATFITVAKK-----GNVAFISQSGALGAGIVYKTIKE 172
            ++G+R++GPNC+G+ N     +  F    ++     G +AF+SQSGA GA I+    + 
Sbjct: 124 KKWGIRVVGPNCLGVTNLENGFDCNFNPPERQARPKFGPIAFMSQSGAFGAAILDWAARH 183

Query: 173 DIGFSKFISVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPV 232
           ++G SKFIS+GNMADLD ++ M YL +  + K I  YIEG+++G+KF  VAK  TK KPV
Sbjct: 184 EVGMSKFISLGNMADLDESDFMLYLKNDPKTKVITAYIEGVKDGKKFFNVAKETTKVKPV 243

Query: 233 IALKAGKSESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQPLP- 291
           I LKAG++E+GA+AA+SHTGSLAGS++IYEA F+Q+G+L A ++ ++ + A+A     P 
Sbjct: 244 IVLKAGRTEAGAKAAASHTGSLAGSYRIYEAVFEQTGILAAKSMRQLFNYAKALAMQKPA 303

Query: 292 RGKRVAIMTNAGGPGVLTADELDKRGLKLANLEEKTIEELRSF-----LPPMAAVKNPVD 346
            G RVAI+TN GG GV+ +D L +RGLKLA L E+T ++ R       LP   +  NPVD
Sbjct: 304 NGDRVAIVTNGGGAGVMMSDGLLERGLKLAELSEETKDKFRKAIEEGKLPEHMSYANPVD 363

Query: 347 MIASARGEDYYRTAKLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNN-GKP 405
           +I  A    Y      +L+DPNVD+L  I +  + A        EGI+  +  V   GKP
Sbjct: 364 VIGDAPSSRYELAINYVLEDPNVDILAVIALFQSPA------LDEGIVDVMDRVKKYGKP 417

Query: 406 VLAMFMAGYVSEKAKELLEKNGIPTYERPEDVASAAYALVEQAKNVGVL 454
           ++ +   G   EK    +EK G+P +E  ED   A YALV+  K +  L
Sbjct: 418 IVFIAPGGEFPEKIARRIEKVGVPVFETVEDGVDAVYALVKYGKYLSEL 466


>gi|11498810 conserved hypothetical protein [Archaeoglobus fulgidus]
           >gi|7448044|pir||B69401 conserved hypothetical protein
           AF1211 - Archaeoglobus fulgidus
           >gi|2649370|gb|AAB90033.1| (AE001020) conserved
           hypothetical protein [Archaeoglobus fulgidus]
           Length = 685
           
 Score =  369 bits (937), Expect = e-101
 Identities = 197/449 (43%), Positives = 290/449 (63%), Gaps = 13/449 (2%)

Query: 2   LDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYKGGNVYPVNVREEEVQGVKAYKSVKDI 61
           ++  F PK +AVIGAS    K+G  + KNL+ + G  VY VN +  E+ G   Y SV  I
Sbjct: 1   MERLFYPKVVAVIGASPQEGKVGNTIMKNLRNFSG-TVYAVNPKYREILGFPCYPSVLKI 59

Query: 62  PGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRYG 121
           P  VDLAIIVVP K V   + +CG K V+G V+I+AGF E G EG K E+ELVE+A RYG
Sbjct: 60  PENVDLAIIVVPAKLVPKAVEECGRKDVEGAVVISAGFKEAGIEGAKLERELVEVAERYG 119

Query: 122 MRIIGPNCVGIMNTHADLNATFITVA-KKGNVAFISQSGALGAGIVYKTIKEDIGFSKFI 180
           ++++GPNC+G++NT   +NATF  VA +KG +AF+SQSGA    ++  + +  +GFSK +
Sbjct: 120 VKLVGPNCLGMINTEIAMNATFSRVAPEKGRIAFLSQSGAFILAVLEWSKRNGVGFSKVV 179

Query: 181 SVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKAGKS 240
           S+GN A LD ++ +EYLA  +    I +Y+EG+ +GRKF+ VAK V ++KPV+ +KAGKS
Sbjct: 180 SLGNKAMLDESDFLEYLAKDDSTDVILIYMEGVEDGRKFMRVAKSVARRKPVVVMKAGKS 239

Query: 241 ESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQPLPRGKRVAIMT 300
           +SGA+AASSHTGSLAGS++ Y AAF+QSGV+ A++++E+   A    +    G  +AI+T
Sbjct: 240 QSGAKAASSHTGSLAGSYEAYRAAFRQSGVIEASSVEELFDFALLLLKYRKAG-NLAILT 298

Query: 301 NAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARGEDYYRTA 360
           N+GGPGV+ AD  D+ G+ LAN   +TI +L+ FLP  +   NPVD++  A  E + R+ 
Sbjct: 299 NSGGPGVMAADACDQFGVPLANFNFETIRKLKEFLPAESNFYNPVDILGDASAERFSRSL 358

Query: 361 KLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPVLAMFMAGYVSEKAK 420
           ++L +D NVD+++ I        +TPT   +  ++A + V  GK  +  FM G   ++++
Sbjct: 359 QILSEDENVDIVLTI--------LTPTAQMD-FLKAAESV-VGKNAVCCFMGGESVDESE 408

Query: 421 ELLEKNGIPTYERPEDVASAAYALVEQAK 449
            +L  +GIP +  P     A   L   +K
Sbjct: 409 RILRSSGIPNFFDPVRAVRAISVLGRYSK 437


>pir||F75054 hypothetical protein PAB1431 - Pyrococcus abyssi (strain Orsay)
           >gi|5458844|emb|CAB50331.1| (AJ248287) hypothetical
           protein [Pyrococcus abyssi]
           Length = 442
           
 Score =  365 bits (926), Expect = e-100
 Identities = 202/454 (44%), Positives = 280/454 (61%), Gaps = 15/454 (3%)

Query: 2   LDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYK-GGNVYPVNVREEEVQGV-KAYKSVK 59
           +DYFF PK +A+ G+  +   +  E+ +N+ +    G + PVN +   V+   + ++  K
Sbjct: 1   MDYFFYPKSVAIFGSFREGA-IAREILRNIVEGGFEGKIIPVNPKGGTVEVAGRRFEIRK 59

Query: 60  DIPGEVDLAIIVVPKKFVKDTLIQCGEKGV-KGVVIITAGFGETGEEGKKEEKELVEIAH 118
            +  EVD++I+V+P K V   + +   KG+ KG V+I+AGF E G    +EE  L++ A 
Sbjct: 60  RLEEEVDVSIVVIPAKLVPGLIREL--KGLTKGAVVISAGFSEVGNVDLEEE--LIKAAK 115

Query: 119 RYGMRIIGPNCVGIMNTHADLNATFITVAKKGNVAFISQSGALGAGIVYKTIKEDIGFSK 178
             G+RIIGPNC GI   H     +F      G +A ISQSGA G   +    +E++GFS 
Sbjct: 116 EAGIRIIGPNCAGIFGVHGKFFGSFEVRVNPGGLALISQSGAFGGAALAMGNEENVGFSA 175

Query: 179 FISVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKAG 238
           F+S GN ADLD ++ + Y AD E  K IALYIEG+++GRKF E  K  T KKPVI LKAG
Sbjct: 176 FVSYGNAADLDESDFLRYFADDENTKVIALYIEGVKDGRKFFEALKYATSKKPVIILKAG 235

Query: 239 KSESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQPLPRGKRVAI 298
           KSESGA+AA SHTGSLAGS++IY+A FKQ   +    ++E+   A+AF      G RVA+
Sbjct: 236 KSESGAKAAQSHTGSLAGSYEIYKAVFKQGNAIEVEEMEELFDAAKAFEMYQSAGSRVAV 295

Query: 299 MTNAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARGEDYYR 358
           +TN+GGPGVL  D+L+K GL++A L E+T+ +LR FLPP  + +NP+D+IA A  E Y R
Sbjct: 296 ITNSGGPGVLATDKLEKLGLEIARLSEETVAKLREFLPPQCSTRNPIDLIADADYERYRR 355

Query: 359 TAKLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPVLAMFMAGYVSEK 418
           T +++ QD NVD L+ ICV P F        +E I RAI E    KP++  FMAG + +K
Sbjct: 356 TIEVVCQDENVDSLLVICVPPIFI------PSEEIARAIIEAKCNKPIIVNFMAGELVKK 409

Query: 419 AKELLEKNGIPTYERPEDVASAAYALVEQAKNVG 452
             ELL  +GI  +  PE  A A Y L  + KN G
Sbjct: 410 GVELLNAHGIKNFPTPERAAKALYWL-SKRKNQG 442


>pir||H71106 hypothetical protein PH0625 - Pyrococcus horikoshii
           >gi|3257031|dbj|BAA29714.1| (AP000003) 440aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 440
           
 Score =  354 bits (900), Expect = 8e-97
 Identities = 198/447 (44%), Positives = 274/447 (61%), Gaps = 16/447 (3%)

Query: 2   LDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYK-GGNVYPVNVR--EEEVQGVKAYKSV 58
           +DYFF PK +A+ G+      +  E+ +N+ +    G + PVN +  E EV G + +   
Sbjct: 1   MDYFFYPKSVAIFGSFRKGS-IAREILRNIVEGGFEGKIIPVNPKGGEVEVSG-RRFIIK 58

Query: 59  KDIPGEVDLAIIVVPKKFVKDTLIQCGEKGV-KGVVIITAGFGETGEEGKKEEKELVEIA 117
           + +   VD++IIV+P K V   + +   KG+ KG V+I+AGF E G    + E+EL+  A
Sbjct: 59  RKLDEFVDVSIIVIPAKLVPGLIREL--KGLTKGAVVISAGFSEVGNV--ELEEELIRAA 114

Query: 118 HRYGMRIIGPNCVGIMNTHADLNATFITVAKKGNVAFISQSGALGAGIVYKTIKEDIGFS 177
              G+RIIGPNC GI   H     +F      G +A ISQSGA G   +    +E++GFS
Sbjct: 115 KESGIRIIGPNCAGIFGVHGKFFGSFEVRVNPGGLALISQSGAFGGAALAMGNEENVGFS 174

Query: 178 KFISVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKA 237
            F+S GN ADLD ++ + Y AD E  K IALYIEG+++GRKF E  K  T KKPVI LKA
Sbjct: 175 AFVSYGNAADLDESDFLRYFADDENTKVIALYIEGVKDGRKFFEALKYATSKKPVIILKA 234

Query: 238 GKSESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQPLPRGKRVA 297
           GKS+SGA+AA SHTGSLAGS++IY+AAFKQ+  +    ++E+   A+AF      G RVA
Sbjct: 235 GKSKSGAKAAQSHTGSLAGSYEIYQAAFKQANAIEVEEMEELFDAAKAFEMYKEAGSRVA 294

Query: 298 IMTNAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARGEDYY 357
           ++TN+GGPGVL  D+L+K GL++A L E T+++LR FLPP  + KNP+D+IA A  E Y 
Sbjct: 295 VITNSGGPGVLATDKLEKLGLEIAQLSEDTVKKLREFLPPQCSTKNPIDLIADADYERYK 354

Query: 358 RTAKLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPVLAMFMAGYVSE 417
           RT +++ QD NVD L+ ICV P F        +E I RAI E    KP++  FM+G +  
Sbjct: 355 RTIEIVCQDENVDSLLVICVPPIFI------PSEEIARAIIEAKCDKPIIVNFMSGELVA 408

Query: 418 KAKELLEKNGIPTYERPEDVASAAYAL 444
              +LL  + I  +  PE  A A Y L
Sbjct: 409 NGVKLLNDHDIKNFPTPERAAKALYWL 435


>gi|11499106 conserved hypothetical protein [Archaeoglobus fulgidus]
           >gi|7483131|pir||F69438 conserved hypothetical protein
           AF1511 - Archaeoglobus fulgidus
           >gi|2649053|gb|AAB89736.1| (AE000998) conserved
           hypothetical protein [Archaeoglobus fulgidus]
           Length = 881
           
 Score =  353 bits (896), Expect = 2e-96
 Identities = 196/457 (42%), Positives = 294/457 (63%), Gaps = 14/457 (3%)

Query: 2   LDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYK-GGNVYPVNVREEEVQGVKAYKSVKD 60
           L +FFNP+ +AVIGAS D +K+G   F NL  Y+  G  YPVN   + + GV+AY ++ +
Sbjct: 191 LKHFFNPESVAVIGASRDVEKVGGRTFYNLLTYRFNGVAYPVNRAAKAIMGVRAYPTISE 250

Query: 61  IPGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRY 120
           +P EV+LA++ VP K+  +   +CG+KGVK ++++TAGF E G EG + +K+LVEI  +Y
Sbjct: 251 VPDEVELAVLSVPVKYALEVAEECGKKGVKALLVLTAGFAEVGGEGVERQKKLVEICRKY 310

Query: 121 GMRIIGPNCVGIMNTHAD--LNATFI-TVAKKGNVAFISQSGALGAGIVYKTIKEDIGFS 177
           GMR+IGPNC+GI+NT  +  L ATF  T   +G++AF SQSGA+G  ++ +     +G S
Sbjct: 311 GMRLIGPNCMGIINTAPETRLLATFAPTPPNEGSIAFASQSGAVGLALMDRVNNYGLGLS 370

Query: 178 KFISVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKA 237
            F+S+GN AD+   +L+E+  +    K I LY E I N RKF  +AKR++KKKP++A+ +
Sbjct: 371 YFVSLGNSADITSNDLIEFWEEDGRTKLIMLYQESIPNPRKFARLAKRISKKKPILAIAS 430

Query: 238 GKSESGARAASSHTGSLAGSWKI-YEAAFKQSGVLVANTIDEMLSMAR-AFTQPLPRGKR 295
           G + +GA+A +SHTG++  S  I  +A FKQ+G++ A++IDE+ S++     QPLP+G R
Sbjct: 431 GVTPAGAKAVASHTGAIVSSSGIAIDALFKQTGIIRASSIDELFSISEFLLHQPLPKGNR 490

Query: 296 VAIMTNAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARGED 355
           V I+TN GG G +T+D   + GL++A L E+T E LR+ LP +A+VKNPVDM ASA    
Sbjct: 491 VCIVTNGGGLGAITSDWCHQVGLEIAELSERTQESLRNLLPEIASVKNPVDMTASADVRM 550

Query: 356 YYRTAKLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNN-GKPVLAMFMAGY 414
           Y +T K + +D NVD +I I  V   +     E  + +I A K  N+ GKPV+ +    Y
Sbjct: 551 YGQTLKTVAEDENVDAIICI-FVAAVSEEKSEEVEKAVISAAKYANSVGKPVVYI----Y 605

Query: 415 VSEKAKE--LLEKNGIPTYERPEDVASAAYALVEQAK 449
           +S  +K+  + ++  +P Y  P   A     +VE AK
Sbjct: 606 ISSDSKDGVIGDEVKVPVYVFPNTAAKVLGKVVEYAK 642


>emb|CAC12278.1| (AL445066) probable acetyl-CoA synthetase [Thermoplasma
           acidophilum]
           Length = 698
           
 Score =  339 bits (859), Expect = 5e-92
 Identities = 185/448 (41%), Positives = 277/448 (61%), Gaps = 13/448 (2%)

Query: 2   LDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQ--YKGGNVYPVNVREEEVQGVKAYKSVK 59
           L   F P+ +AVIGAS D  K+GY++ +NLK+  Y+G  VYPVN +   + G   Y S+ 
Sbjct: 8   LKSLFYPESVAVIGASADKTKIGYQIVRNLKEGGYQG-KVYPVNRKGGNILGYTVYPSIG 66

Query: 60  DIPGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHR 119
           D+P +VDLAII VP +   +   +CG+KGV G++++ +GF E G   K  E +LVE+  +
Sbjct: 67  DVPDKVDLAIISVPAEHTPEAAEECGKKGVFGIIVVASGFSEVGR--KDLEDQLVEVCRK 124

Query: 120 YGMRIIGPNCVGIMNTHADLNATFIT-VAKKGNVAFISQSGALGAGIVYKTIKEDIGFSK 178
           Y MR++GPN VG+MN    LNA+F   +   G +  +SQSGAL  G+   T     G S 
Sbjct: 125 YNMRLLGPNVVGLMNNVLKLNASFAPYLPYPGTIGMVSQSGALIVGLDAMTWSNKTGTSF 184

Query: 179 FISVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKAG 238
            IS+GNMADLDF++L+ +LA+      I+LY EG++ GR+FI+ A+ +  KKP++ LK+G
Sbjct: 185 LISIGNMADLDFSDLVSFLAEDNNVSCISLYTEGLKAGRRFIDTARSI--KKPIVMLKSG 242

Query: 239 KSESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFT-QPLPRGKRVA 297
            S+ G+ AA+SHTGSLAGS ++Y+ A KQ+GV+ AN+I+E+  ++   + QP   G  + 
Sbjct: 243 ISKHGSVAAASHTGSLAGSHRVYDGALKQAGVVRANSIEELFDLSLTLSLQPPMGGDNLM 302

Query: 298 IMTNAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARGEDYY 357
           ++TN GG GVL  D+ +  G+ L    +    ++R  +P   + KNP+DM A A  E Y 
Sbjct: 303 VVTNGGGIGVLATDQAELSGIPLQTPSDDLQAKIRQVIPSFGSTKNPIDMSAMATPEIYA 362

Query: 358 RTAKLLLQDPNVDMLIAI-CVVPTFAGMTPTEHAEGIIRAIKEVNNGKPVLAMFMAGYVS 416
            T K +++D +VD L+ + C V   A + P++ A+GII  +   N   PV+A F+ G  S
Sbjct: 363 DTIKTVMEDDSVDGLVVLYCEV---ANLDPSDAAKGIINGVLSSNRKIPVVAGFVGGEHS 419

Query: 417 EKAKELLEKNGIPTYERPEDVASAAYAL 444
           + A   L KNGIPT++ P+    A  AL
Sbjct: 420 KNASLYLIKNGIPTFDSPDKAVKAMAAL 447


>gb|AAF88064.1|AF286346_1 (AF286346) acetyl-CoA synthetase [Entamoeba histolytica]
           Length = 713
           
 Score =  327 bits (829), Expect = 2e-88
 Identities = 182/442 (41%), Positives = 268/442 (60%), Gaps = 17/442 (3%)

Query: 6   FNPKGIAVIGASNDPKKLGYEVFKNLKQ--YKGGNVYPVNVREEEVQGVKAYKSVKDIPG 63
           FNPK + VIGAS+  + +GY V  N+ +  YKG N+YPV  R+ E+ G K Y  +  I  
Sbjct: 7   FNPKSVPVIGASDRKESVGYAVMNNMIKGGYKG-NLYPVG-RKPELFGKKCYAKIGKIEE 64

Query: 64  EVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRYGMR 123
           +VDLA+I +P KFV    I+CGE GVKG++IITAGF E GEEGKK   E+     +Y MR
Sbjct: 65  KVDLAVIAIPAKFVPGVCIECGEAGVKGLIIITAGFAEAGEEGKKMCIEIQATCQKYNMR 124

Query: 124 IIGPNCVGIMNTHADLNATFITVAKK-GNVAFISQSGALGAGIVYKTIKEDIGFSKFISV 182
           +IGPNC+GI+N    +NA+F +V  + G VAFISQSGAL   I+     + +GFS F+S+
Sbjct: 125 MIGPNCLGIINPRDGVNASFASVMPEAGGVAFISQSGALCTAILDWAANQHVGFSYFVSI 184

Query: 183 GNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKAGKSES 242
           G+  D D+A+L E+ A   +  +I +YIE I++ +KF+  A+     KP+I LKAGKS  
Sbjct: 185 GSSIDTDYADLFEFFAKDPKVTSILMYIESIKDAKKFVLRAREFAADKPIILLKAGKSSE 244

Query: 243 GARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAF-TQPLPRGKRVAIMTN 301
           GA AA SHTGSLAG+  +Y+A F + G +  ++I ++   A    TQ +P+  R+ I+TN
Sbjct: 245 GAAAAMSHTGSLAGNDAVYDAVFDRCGCIRVDSICDLWDCAHVLATQNIPQNNRLCIITN 304

Query: 302 AGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARGEDYYRTAK 361
           AGGPGV++ D L      LA L E T+ EL +FL P  +  NPVD++  A    Y +T  
Sbjct: 305 AGGPGVISTDRLVSVHGHLAKLSESTMNELNAFLSPFWSHSNPVDVLGDATAGVYQKTLD 364

Query: 362 LLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPVLAMFMAGYVSEKAK- 420
           ++++DP +D ++ +        +TP    + +  A   V +G         G+V++K++ 
Sbjct: 365 IVIKDPQIDGVVVV--------LTPQAMTDPVAVAKSLVEHGPYQNQSLPHGWVNQKSEA 416

Query: 421 --ELLEKNGIPTYERPEDVASA 440
             ++LE+  IP +E PE   +A
Sbjct: 417 GVKILEEGKIPNFETPERAVTA 438


>gb|AAK42002.1| Conserved hypothetical protein [Sulfolobus solfataricus]
           Length = 660
           
 Score =  323 bits (818), Expect = 3e-87
 Identities = 177/440 (40%), Positives = 264/440 (59%), Gaps = 15/440 (3%)

Query: 2   LDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYKGGNVYPVNVREEEVQGVKAYKSVKDI 61
           L+Y F P+ IAV+GAS   +K+G  +F+NL     G +YP+N + E+V+GVKAYKSVK+I
Sbjct: 4   LNYLFKPRSIAVVGASRHKEKVGNVIFRNLLSTFQGKLYPINTKAEDVEGVKAYKSVKEI 63

Query: 62  PGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRYG 121
           P ++DL +I VP++ V  T+ +  EKGVK  ++ITAGF E GEE  K E E++ IA + G
Sbjct: 64  PDDIDLGVIAVPREVVPQTMEEFVEKGVKASIVITAGFREVGEE--KLENEVISIARKGG 121

Query: 122 MRIIGPNCVGIMNTHADLNATFI-TVAKKGNVAFISQSGALGAGIVYKTIKEDIGFSKFI 180
           +R++GPN  GI+    + NATF  T  K+GNV  + QSG LG  ++    K  IG S  +
Sbjct: 122 IRVLGPNTFGIITP--EFNATFTYTDVKRGNVGLVVQSGGLGVYMLNWAQKYRIGISYMV 179

Query: 181 SVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKAGKS 240
           S+GN AD+   E++ YL+   E +AI +Y+EG+ +G  F+E     T++KPV+ LK G S
Sbjct: 180 SLGNQADVKEYEVINYLSKDAETRAIFVYLEGVSDGNAFLEELPEATRRKPVVFLKGGVS 239

Query: 241 ESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQPLPRGKRVAIMT 300
            SGA AA +HTGSLAGS+++++AA    G ++ + + +ML++A+      P  + + ++T
Sbjct: 240 SSGASAAKTHTGSLAGSFEVFKAAVNTIGGILVDNLHDMLNLAKILMYSEPISEELLVIT 299

Query: 301 NAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARGEDYYRTA 360
           N+GG GVL +DE+DK GL+L  + E   +EL   LPP +  KNP+D+   A  E Y+   
Sbjct: 300 NSGGHGVLVSDEIDKNGLRLVEIPEWMKKELTKILPPTSLPKNPLDLTGDADRERYHNAL 359

Query: 361 KLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPVLAMFMAGYVSEKAK 420
           K++    ++D     C         P      + R I     GK V+ + M G   + A 
Sbjct: 360 KIV---SSLD-----CTKLVIVQSLPMVSCSDVARVISNF-KGKGVIGVTM-GLDEDMAL 409

Query: 421 ELLEKNGIPTYERPEDVASA 440
           ++LE  GIP Y  PED   A
Sbjct: 410 KILETTGIPGYTFPEDAVKA 429


>gb|AAD44021.1|AF107206_1 (AF107206) acetyl-CoA synthetase [Giardia intestinalis]
           Length = 726
           
 Score =  309 bits (784), Expect = 3e-83
 Identities = 176/451 (39%), Positives = 266/451 (58%), Gaps = 6/451 (1%)

Query: 2   LDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYK-GGNVYPVNVREEEVQGVKAYKSVKD 60
           L +  NP  +AVIGAS +  K+G  V  N+K+    G VYP+N    E+ G K YKSV D
Sbjct: 15  LSFLTNPASVAVIGASPNAGKVGNTVVTNIKESGYTGKVYPINPTATEILGYKTYKSVLD 74

Query: 61  IPGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRY 120
           +P  +D+ I+V+P K V     +C +K VK +V+ITAGF E G EG + E++L +I    
Sbjct: 75  VPDSIDVVIVVIPSKAVLAAAKECAQKKVKSLVVITAGFKEIGGEGVQMEQDLTKICKDA 134

Query: 121 GMRIIGPNCVGIMNTHADLNATFITVA-KKGNVAFISQSGALGAGIVYKTIKEDIGFSKF 179
           G+R++GPNC+GI+  +  LN TF +    KG++AF+SQSGA+   I+   +   IGFS F
Sbjct: 135 GIRLVGPNCLGIVTPN--LNCTFASAKPSKGSIAFLSQSGAMLTSILDWALTNGIGFSNF 192

Query: 180 ISVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKAGK 239
           IS+GN AD+D  +L+  +A+      I LY+E I +GRKF+E       KKPVI LK+G 
Sbjct: 193 ISLGNKADVDEVDLIMEVAEDPNTDIILLYLESIVDGRKFLEQIPTCVHKKPVIILKSGT 252

Query: 240 SESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAF-TQPLPRGKRVAI 298
           S +GA AASSHTG+LAG+   ++ AF+++GVL A T+ ++  + R F +  LP+G    I
Sbjct: 253 SAAGAAAASSHTGALAGNDIAFDLAFEKAGVLRAATMSDLFDLGRLFVSHRLPKGDNFVI 312

Query: 299 MTNAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARGEDYYR 358
           +TNAGGPG++T D  +   + +A L +KT E L   LP  A+VKNPVD++  A  + Y  
Sbjct: 313 VTNAGGPGIVTTDAFETYHVGMAALSDKTKEALAKVLPGEASVKNPVDIVGDAPPKRYED 372

Query: 359 TAKLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPVLAMFMAGYVSEK 418
             ++  ++P   +  A+ +V       P E AE   R   +  + + V++ FM G   ++
Sbjct: 373 ALEICFKEPPETVAGAVILVTPQGQTKPCEVAELCTRMYAKYPD-RLVVSAFMGGLTMQE 431

Query: 419 AKELLEKNGIPTYERPEDVASAAYALVEQAK 449
             ++L    +P +  PE    A  A+++  K
Sbjct: 432 PSKILNNAKMPVFPFPEPAIHATGAVLKYRK 462


>gi|11498792 conserved hypothetical protein [Archaeoglobus fulgidus]
           >gi|7483097|pir||G69398 conserved hypothetical protein
           AF1192 - Archaeoglobus fulgidus
           >gi|2649402|gb|AAB90053.1| (AE001022) conserved
           hypothetical protein [Archaeoglobus fulgidus]
           Length = 664
           
 Score =  301 bits (763), Expect = 1e-80
 Identities = 175/457 (38%), Positives = 273/457 (59%), Gaps = 22/457 (4%)

Query: 2   LDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYK-GGNVYPVNVREEEVQGVKAYKSVKD 60
           + +FF  K +AVIGAS +  K G  V  NLK     G VYPVN    E+ G K Y SV+ 
Sbjct: 218 ISFFFKAKSVAVIGASRNLLKPGGRVLSNLKHLGFRGKVYPVNPNAGEILGYKCYPSVRA 277

Query: 61  IPGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRY 120
           IP +VDLA+I VP K   + + +C EKGVKG+++++AGF E  E+GK+ E+++VEIA + 
Sbjct: 278 IPDKVDLAVIAVPSKNAIEVVKECAEKGVKGIIVLSAGFAEGWEQGKELERQIVEIARKS 337

Query: 121 GMRIIGPNCVGIMNTHADLNATFITVAK--KGNVAFISQSGALGAGIVYKTIKEDIGFSK 178
           GMRI+GPN +GI++  + L + F  + K  +GN+  ++QSGA+   I+       +GFSK
Sbjct: 338 GMRIVGPNTMGILDPESGLTSFFSVLRKIGQGNIGVLAQSGAVANFILLPL--WHVGFSK 395

Query: 179 FISVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKAG 238
            +++GN AD+   E++ +L   E+ + +A Y+EG  NGRKF E+ K  T  KP++ LK+G
Sbjct: 396 IVAIGNKADVGEVEVLNFLLKDEKTRVVAAYLEGFTNGRKFYELMKAST--KPIVVLKSG 453

Query: 239 KSESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFT-QPLPRGKRVA 297
           ++E+G R+A SHT S++ S +I+EAA KQ+GV      +E++  A+A   QPLPRG RV 
Sbjct: 454 RTEAGKRSALSHTASISTSEEIFEAACKQAGVAKVYDFEELVDAAKALALQPLPRGTRVG 513

Query: 298 IMTNAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDM--IASARGED 355
           ++  +G   V++AD + + GL+LA   EKT+E L    P   ++ NP+D+  IA   G++
Sbjct: 514 VIQPSGAECVMSADAVVENGLELAKYSEKTLERLYELAPEWHSINNPLDLYPIAEKSGDE 573

Query: 356 YY-RTAKLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPVLAMFMAGY 414
            +    K+  +D N+D ++A   +P+   +       G+  +       KPVL   M   
Sbjct: 574 VFNEVLKVFNEDENIDAIVAGVFIPSIMKL-------GVDFSWTR-KFSKPVL-FTMKDD 624

Query: 415 VSE--KAKELLEKNGIPTYERPEDVASAAYALVEQAK 449
           + E  +A+  +E++G+P Y  PE    A   +V  AK
Sbjct: 625 IEELRQARIEIERSGVPVYPTPERAVRALRHMVTVAK 661


>pir||T35770 hypothetical protein SC8A6.03c SC8A6.03c - Streptomyces coelicolor
           >gi|3288603|emb|CAA19775.1| (AL031013) hypothetical
           protein SC8A6.03c [Streptomyces coelicolor A3(2)]
           Length = 714
           
 Score =  295 bits (747), Expect = 7e-79
 Identities = 170/456 (37%), Positives = 252/456 (54%), Gaps = 16/456 (3%)

Query: 8   PKGIAVIGASNDPKKLGYEVFKNLKQYK-GGNVYPVNVREEEVQGVKAYKSVKDIPGEVD 66
           P  +AVIGAS +P K+G  V +NL      G ++PVN + +++ G KAYKSV D+PGEVD
Sbjct: 261 PASVAVIGASGEPGKIGNSVMRNLVDGGFAGEIHPVNPKADDILGRKAYKSVTDVPGEVD 320

Query: 67  LAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRYGMRIIG 126
           +A+  +P +FV   L + G K +   V+I +GF ETGE+  ++E  +V +A R+G+R++G
Sbjct: 321 VAVFAIPARFVAAALEEVGRKRIPNAVLIPSGFAETGEQALQDE--IVAVAERHGVRLLG 378

Query: 127 PNCVGIMNTHADLNATFITVAK-KGNVAFISQSGALGAGIVYKTIKEDIGFSKFISVGNM 185
           PN  G  +T  DL ATF T    KG VA  SQSG +G  I+        G S  + +GN 
Sbjct: 379 PNIYGYYSTWQDLCATFCTPYDVKGGVALTSQSGGIGMAILGFARTTKTGVSAIVGLGNK 438

Query: 186 ADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKAGKSESGAR 245
           +DLD  +L+ +  +    + IA+++E +++GR F+E A+    +KPV+ LKAG++ +GA+
Sbjct: 439 SDLDEDDLLTWFGEDPHTECIAMHLEDLKDGRAFVEAARATVPRKPVVVLKAGRTAAGAK 498

Query: 246 AASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAF-TQPLPRGKRVAIMTNAGG 304
           AA SHTG+LAG   +Y+   +Q+GV+ A  ++EML  ARA    P P G  V I+T AGG
Sbjct: 499 AAGSHTGALAGDDAVYDDILRQAGVIRAPGLNEMLEYARALPVLPAPEGDNVVIITGAGG 558

Query: 305 PGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARGEDYYRTAKLLL 364
            GVL +D +   GL L  +        R+F+PP  A  NPVD+        Y  T +L L
Sbjct: 559 SGVLLSDAVTDNGLSLMEIPPDLDRAFRAFIPPFGAAGNPVDITGGEPPSTYEATIRLGL 618

Query: 365 QDPNVDMLIA----ICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPVLAMFMAGYVSEKAK 420
           +DP +  L+       V P    M   E    ++   +E    KPV+A        E+A 
Sbjct: 619 EDPRIHALVLGYWHTIVTPP---MVFAELTARVVAEFRERGVEKPVVASLAGDVEVEEAC 675

Query: 421 ELLEKNGIPTY----ERPEDVASAAYALVEQAKNVG 452
           + L + G+  Y    E+P  V  A Y     A  +G
Sbjct: 676 QYLFERGVVAYPYTTEKPVAVLGAKYRWARAAGLLG 711


>gi|11499522 conserved hypothetical protein [Archaeoglobus fulgidus]
           >gi|7483184|pir||A69492 conserved hypothetical protein
           AF1938 - Archaeoglobus fulgidus
           >gi|2648606|gb|AAB89317.1| (AE000970) conserved
           hypothetical protein [Archaeoglobus fulgidus]
           Length = 673
           
 Score =  279 bits (706), Expect = 5e-74
 Identities = 168/456 (36%), Positives = 264/456 (57%), Gaps = 21/456 (4%)

Query: 6   FNPKGIAVIGASNDPKKLGYEVFKNLKQYKG-GNVYPVNVREEEVQGVKAYKSVKDIPGE 64
           F PK +AVIGAS    K G+ +  NLKQ    G +YPVN   +++  +K Y S+ DIP E
Sbjct: 222 FYPKSVAVIGASRTVGKPGFNIVWNLKQNGFMGKIYPVNPNADKILELKCYPSILDIPDE 281

Query: 65  VDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRYGMRI 124
           VD+AII VP K V + + +C +KG+KG VI+++GF E GE+G + E+ ++EIA ++G+RI
Sbjct: 282 VDMAIIAVPAKIVPEVMAECAQKGIKGAVIVSSGFSEEGEKGAEYERRVLEIAKKHGIRI 341

Query: 125 IGPNCVGIMNTHADLNATFI--TVAKKGNVAFISQSGALGAGIVYKTIKED---IGFSKF 179
            GPN  G++NT      +F    V KKGN+  I+Q+G L  GI+   +  +   IGFSK 
Sbjct: 342 FGPNTTGVLNTENGFITSFAIQPVIKKGNIGIIAQTG-LFLGIMMDIVTSNHPSIGFSKI 400

Query: 180 ISVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKAGK 239
           + +GN  D++  E++++L   E+ K I +Y+EGI+NGR F +VA   + +KP++  K+G+
Sbjct: 401 VGMGNKIDVEDYEVLDFLLKDEQTKVIGIYMEGIKNGRAFYDVAS--SAEKPIVVFKSGR 458

Query: 240 SESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFT-QPLPRGKRVAI 298
           +E G +AA SHT S+ G   +++A  +Q+ ++   + DE+  + +AF+ QPLP+G RVAI
Sbjct: 459 TEYGQKAAMSHTASICGDDDVFDAVCRQANLVRVYSFDELFDVTKAFSLQPLPKGDRVAI 518

Query: 299 MTNAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVD---MIASARGED 355
           +   G   V  +D     GLKLA   + T++++    P    V NP+D   M+       
Sbjct: 519 IHYTGSGCVQGSDAAYFAGLKLAEFSKDTVDKISEVTPEWHNVNNPIDIWPMVEYYGAFK 578

Query: 356 YYRTA-KLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPV-LAMFMAG 413
            Y+TA + +++D  VD +IA CV   +A        E   +++K+   GKP+   +  A 
Sbjct: 579 AYQTAIEAVMEDEGVDSVIA-CV---WANRLINADFEPDYKSLKKY--GKPIYFCVEGAR 632

Query: 414 YVSEKAKELLEKNGIPTYERPEDVASAAYALVEQAK 449
            V    K  LE NGIP Y    +  +    + + AK
Sbjct: 633 DVVFDHKNALELNGIPVYTNVINAVNVLGKVTKYAK 668


>gi|11498537 conserved hypothetical protein [Archaeoglobus fulgidus]
           >gi|7483066|pir||D69366 conserved hypothetical protein
           AF0932 - Archaeoglobus fulgidus
           >gi|2649664|gb|AAB90306.1| (AE001039) conserved
           hypothetical protein [Archaeoglobus fulgidus]
           Length = 666
           
 Score =  279 bits (706), Expect = 5e-74
 Identities = 161/451 (35%), Positives = 259/451 (56%), Gaps = 12/451 (2%)

Query: 2   LDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYKGGNVYPVNVREEEVQGVKAYKSVKDI 61
           + +FF  + +AVIGAS +P K+G  V ++L   K   +YP+N    E+ G+KAY SVK +
Sbjct: 219 ISFFFKARSVAVIGASTNPIKVGNSVVRSLMSNKNLRIYPINPNASEILGLKAYPSVKSL 278

Query: 62  PGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETG-EEGKKEEKELVEIAHRY 120
           P   D+AI+ VP +FV D + +  E GVKGVVII++GF E   EEGK  E+ L EIA +Y
Sbjct: 279 PEVPDIAIVTVPAEFVLDAVREAAEAGVKGVVIISSGFKEAEVEEGKVREERLREIARKY 338

Query: 121 GMRIIGPNCVGIMNTHADLNATFITV---AKKGNVAFISQSGALGAGIVYKTIKEDIGFS 177
           G+RI+GPN  GI++    +NA+F  +    KKG +A +SQSG +   I++K    D GFS
Sbjct: 339 GIRIVGPNTFGIVSVVGGINASFTPMFSEVKKGRIALVSQSGGICHYIIHKF--RDSGFS 396

Query: 178 KFISVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKA 237
             + +GN  D+DF ++M +L + E    +A+Y+EGI NGR   E  KR+  +K V+ +K+
Sbjct: 397 HILHLGNRCDVDFPDVMRFLREDENTDVVAVYVEGIDNGRGLFEELKRLCSEKKVVVMKS 456

Query: 238 GKSESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQPLPRGKRVA 297
           G+S    +A+ SHTGS+AG ++++ +A KQ+G +V  T  E++  A A  +    G  VA
Sbjct: 457 GRSSVADKASVSHTGSMAGDYRVFASAMKQAGAVVVETPTELIDTAIAMEKFEVSG-GVA 515

Query: 298 IMTNAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARG-EDY 356
           ++T   G G++ AD ++  G +LA   E+T+ +L+S LPP+   +NPVD+  S    + +
Sbjct: 516 VLTIQAGLGIVAADIIESSGGRLARFGEETVRKLKSLLPPITLRENPVDLSFSGLNLKVF 575

Query: 357 YRTAKLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPVLAMFMAGYVS 416
                 + +D +V +++ +  V   + + P E    I+  I + +    +L         
Sbjct: 576 AEVIDTVCRDDDVGLVMFLYAVAPPSWVLPAEVISQIMGRITKPS----ILGYSSTPENY 631

Query: 417 EKAKELLEKNGIPTYERPEDVASAAYALVEQ 447
            + KE L+ +    ++  E  A  A  L E+
Sbjct: 632 AEIKEALKGSKTLIFDSVERAAKVAAILSEK 662


>pir||C82443 conserved hypothetical protein VCA0574 [imported] - Vibrio cholerae
           (group O1 strain N16961) >gi|9657984|gb|AAF96476.1|
           (AE004388) conserved hypothetical protein [Vibrio
           cholerae]
           Length = 893
           
 Score =  261 bits (660), Expect = 1e-68
 Identities = 156/454 (34%), Positives = 251/454 (54%), Gaps = 7/454 (1%)

Query: 2   LDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYK-GGNVYPVNVREEEVQGVKAYKSVKD 60
           L+    PK +AVIGAS    + G  V KNL Q    G + PV      V GV AYK++ D
Sbjct: 4   LNQLLRPKSVAVIGASVRSFRAGNIVMKNLLQGGFDGAIMPVTPYYPAVCGVLAYKTISD 63

Query: 61  IPGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRY 120
           +P   D+AI+            Q  EKGVK V+++++       +G++ + + + IA   
Sbjct: 64  LPIVPDIAILCTHASRNVSLFKQLAEKGVKQVIVLSSDMYSLDAQGEEIQAQCMTIAKSV 123

Query: 121 GMRIIGPNCVGIMNTHADLNATFITV-AKKGNVAFISQSGALGAGIVYKTIKEDIGFSKF 179
            MRI+GPN +G++      N +F  V A KGN+AF+SQS A+   I+     + IGFS F
Sbjct: 124 NMRILGPNSLGLILPWMQFNGSFSPVSALKGNIAFVSQSAAVCTTILDWANDKGIGFSAF 183

Query: 180 ISVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKAGK 239
           IS+GN +D+DFA+L++ L+  +   AI LY++ IR+ R+F+  A+  ++ + ++ LK G+
Sbjct: 184 ISLGNASDIDFADLLDTLSTDKHTDAILLYVDTIRDARRFMSAARAASRNRRILVLKGGR 243

Query: 240 SESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQPLP-RGKRVAI 298
           +++G +AA  HTG       IY++A +++G+L  N   E+ +     T  +P RG+R+AI
Sbjct: 244 TKAGRKAAQMHTGGDDTLDIIYDSAIRRTGMLRVNNTHELFAAVETLTHSVPLRGERLAI 303

Query: 299 MTNAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARGEDYYR 358
           +TN GGP ++  D L +RG KLA LE++  E+L   LP   +  NPVD++  A    Y  
Sbjct: 304 ITNGGGPAIMAVDALLERGGKLAQLEDEIYEKLNQSLPQSWSHSNPVDIVGDADHLRYVS 363

Query: 359 TAKLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGK--PVLAMFMAGYVS 416
           T  +LL+  N+D ++ +      A    T  A+ ++ A+++    K   +L  +     +
Sbjct: 364 TLNILLESENIDAILIMHSPSAIAHSEQT--AQALVEAVQKHPRAKRFNILTNWSGELSA 421

Query: 417 EKAKELLEKNGIPTYERPEDVASAAYALVEQAKN 450
           + A+ L  + GIPTY  PE   +A   LVE  +N
Sbjct: 422 KPARTLFNQAGIPTYRTPESAVTAFMHLVEYRRN 455


>dbj|BAA10925.1| (D64044) hypothetycal 67KD protein fragment in UNG 3' region
           [Escherichia coli]
           Length = 612
           
 Score =  234 bits (590), Expect = 2e-60
 Identities = 151/454 (33%), Positives = 238/454 (52%), Gaps = 19/454 (4%)

Query: 2   LDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYK-GGNVYPVNVREEEVQGVKAYKSVKD 60
           L+    PK IAVIGAS  P + GY + +NL      G V PV    + V GV A+  +  
Sbjct: 6   LEALLRPKSIAVIGASMKPNRAGYLMMRNLLAGGFNGPVLPVTPAWKAVLGVLAWPDIAS 65

Query: 61  IPGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRY 120
           +P   DLA++          L + GEKG K  +I++A           + ++L   A R+
Sbjct: 66  LPFTPDLAVLCTNASRNLALLEELGEKGCKTCIILSAP--------ASQHEDLRACALRH 117

Query: 121 GMRIIGPNCVGIMNTHADLNATFITVA-KKGNVAFISQSGALGAGIVYKTIKEDIGFSKF 179
            MR++GPN +G++     LNA+F  V  K+G +AFISQS A+   I+    +  +GFS F
Sbjct: 118 NMRLLGPNSLGLLAPWQGLNASFSPVPIKRGKLAFISQSAAVSNTILDWAQQRKMGFSYF 177

Query: 180 ISVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKAGK 239
           I++G+  D+D  EL++YLA   +  AI LY+E + + R+F+  A+  ++ KP++ +K+G+
Sbjct: 178 IALGDSLDIDVDELLDYLARDSKTSAILLYLEQLSDARRFVSAARSASRNKPILVIKSGR 237

Query: 240 SESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQPLP-RGKRVAI 298
           S +  R  +    + AG    ++AA +++G+L      E+ S     +   P RG R+ I
Sbjct: 238 SPAAQRLLN----TTAGMDPAWDAAIQRAGLLRVQDTHELFSAVETLSHMRPLRGDRLMI 293

Query: 299 MTNAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARGEDYYR 358
           ++N   P  L  D L  R  KLA L E+T ++LR  LP   A+ NP+D+   A  E Y +
Sbjct: 294 ISNGAAPAALALDALWSRNGKLATLSEETCQKLRDALPEHVAISNPLDLRDDASSEHYIK 353

Query: 359 TAKLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPV--LAMFMAGYVS 416
           T  +LL   + D L+ I      A    TE A+ +I A+K     K V  L  +   + S
Sbjct: 354 TLDILLHSQDFDALMVI--HSPSAAAPATESAQVLIEAVKHHPRSKYVSLLTNWCGEHSS 411

Query: 417 EKAKELLEKNGIPTYERPEDVASAAYALVEQAKN 450
           ++A+ L  + G+PTY  PE   +A   +VE  +N
Sbjct: 412 QEARRLFSEAGLPTYRTPEGTITAFMHMVEYRRN 445


>sp|P76594|YFIQ_ECOLI HYPOTHETICAL 98.0 KD PROTEIN IN UNG-PSSA INTERGENIC REGION
           >gi|7466397|pir||G65036 hypothetical protein b2584 -
           Escherichia coli (strain K-12)
           >gi|1788938|gb|AAC75637.1| (AE000344) orf, hypothetical
           protein [Escherichia coli K12]
           Length = 886
           
 Score =  234 bits (590), Expect = 2e-60
 Identities = 151/454 (33%), Positives = 238/454 (52%), Gaps = 19/454 (4%)

Query: 2   LDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYK-GGNVYPVNVREEEVQGVKAYKSVKD 60
           L+    PK IAVIGAS  P + GY + +NL      G V PV    + V GV A+  +  
Sbjct: 6   LEALLRPKSIAVIGASMKPNRAGYLMMRNLLAGGFNGPVLPVTPAWKAVLGVLAWPDIAS 65

Query: 61  IPGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRY 120
           +P   DLA++          L + GEKG K  +I++A           + ++L   A R+
Sbjct: 66  LPFTPDLAVLCTNASRNLALLEELGEKGCKTCIILSAP--------ASQHEDLRACALRH 117

Query: 121 GMRIIGPNCVGIMNTHADLNATFITVA-KKGNVAFISQSGALGAGIVYKTIKEDIGFSKF 179
            MR++GPN +G++     LNA+F  V  K+G +AFISQS A+   I+    +  +GFS F
Sbjct: 118 NMRLLGPNSLGLLAPWQGLNASFSPVPIKRGKLAFISQSAAVSNTILDWAQQRKMGFSYF 177

Query: 180 ISVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKAGK 239
           I++G+  D+D  EL++YLA   +  AI LY+E + + R+F+  A+  ++ KP++ +K+G+
Sbjct: 178 IALGDSLDIDVDELLDYLARDSKTSAILLYLEQLSDARRFVSAARSASRNKPILVIKSGR 237

Query: 240 SESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQPLP-RGKRVAI 298
           S +  R  +    + AG    ++AA +++G+L      E+ S     +   P RG R+ I
Sbjct: 238 SPAAQRLLN----TTAGMDPAWDAAIQRAGLLRVQDTHELFSAVETLSHMRPLRGDRLMI 293

Query: 299 MTNAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARGEDYYR 358
           ++N   P  L  D L  R  KLA L E+T ++LR  LP   A+ NP+D+   A  E Y +
Sbjct: 294 ISNGAAPAALALDALWSRNGKLATLSEETCQKLRDALPEHVAISNPLDLRDDASSEHYIK 353

Query: 359 TAKLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPV--LAMFMAGYVS 416
           T  +LL   + D L+ I      A    TE A+ +I A+K     K V  L  +   + S
Sbjct: 354 TLDILLHSQDFDALMVI--HSPSAAAPATESAQVLIEAVKHHPRSKYVSLLTNWCGEHSS 411

Query: 417 EKAKELLEKNGIPTYERPEDVASAAYALVEQAKN 450
           ++A+ L  + G+PTY  PE   +A   +VE  +N
Sbjct: 412 QEARRLFSEAGLPTYRTPEGTITAFMHMVEYRRN 445


>emb|CAA10043.1| (AJ012480) pimeloyl-CoA synthetase [Pseudomonas mendocina]
           Length = 711
           
 Score =  199 bits (501), Expect = 5e-50
 Identities = 120/352 (34%), Positives = 189/352 (53%), Gaps = 9/352 (2%)

Query: 8   PKGIAVIGASNDPKKLGYE-VFKNLKQYKGGNVYPVNVREEEVQGVKAYKSVKDIPGEVD 66
           P+ +AV+GAS+DP ++G   +   L+    G + PVN    E+QG+ AY SV  +P   D
Sbjct: 20  PRSVAVVGASSDPHRIGGRPIAYMLRNGFTGRILPVNPNRTEIQGLPAYASVDALPEAPD 79

Query: 67  LAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRYGMRIIG 126
           +AII VP   V +T+   G KG +  ++ ++GF E GEEG   +  +VE A    MR++G
Sbjct: 80  VAIIAVPAPQVLETVQVLGRKGARSAIVFSSGFSEVGEEGVAMQDAIVEAARAANMRLLG 139

Query: 127 PNCVGIMNTHADLNATFITVAKK-----GNVAFISQSGALGAGIVYKTIKEDIGFSKFIS 181
           PN +G+ N +    A F T  ++     G V   +QSGA GA ++  + +  +G    ++
Sbjct: 140 PNALGVFNANLGYYAFFSTSLERGIPLAGRVGIATQSGAYGAHLLGLSRQRGLGTPICVA 199

Query: 182 VGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKK-KPVIALKAGKS 240
            GN AD+   + + +L ++ E   +  Y E IRN   F+   +   +  KPVI  K G+S
Sbjct: 200 TGNEADVTLGDAIGWLVESPEVDVVMAYAESIRNVDSFLAALEAAHRAGKPVILHKVGRS 259

Query: 241 ESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQP-LPRGKRVAIM 299
           E G RAA SHT SLAG  K+ +A      V+ A T +E++ +A   TQ  +P    + ++
Sbjct: 260 ELGGRAAMSHTASLAGDDKVLDAVLADYAVVRARTTEELVDIAYLATQRIIPVNNSLGMI 319

Query: 300 TNAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASA 351
           T +GG G++ +D  +  GL +  + E+    L+  L   A+  NPVD  A A
Sbjct: 320 TVSGGAGIIVSDAAEDVGLPMPPMPEEAQARLKQRL-HYASPLNPVDCTAQA 370


>pir||B83518 pimeloyl-CoA synthetase PA1017 [imported] - Pseudomonas aeruginosa
           (strain PAO1) >gi|9946928|gb|AAG04406.1|AE004534_4
           (AE004534) pimeloyl-CoA synthetase [Pseudomonas
           aeruginosa]
           Length = 715
           
 Score =  197 bits (496), Expect = 2e-49
 Identities = 117/352 (33%), Positives = 191/352 (54%), Gaps = 9/352 (2%)

Query: 8   PKGIAVIGASNDPKKLGYE-VFKNLKQYKGGNVYPVNVREEEVQGVKAYKSVKDIPGEVD 66
           P+ +AVIGAS+DP ++G   +   L+    G + PVN    E+QG+ A+ SV ++P   D
Sbjct: 24  PRSVAVIGASSDPTRIGGRPIAYMLRHGYAGQILPVNPNRAEIQGLPAFASVAELPQAPD 83

Query: 67  LAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRYGMRIIG 126
           +AI+ VP   V +T+   G +G +  ++ ++GF E GE G   +  +V  A  +GMR++G
Sbjct: 84  VAIVAVPAPQVLETVRALGRQGARSAIVFSSGFSEVGEAGAAMQDAVVAAAREHGMRLLG 143

Query: 127 PNCVGIMNTHADLNATFIT-----VAKKGNVAFISQSGALGAGIVYKTIKEDIGFSKFIS 181
           PN +G  N++    A F T     V   G V   +QSGA GA ++    +  +G    ++
Sbjct: 144 PNALGAFNSNLGYYAFFSTSLERGVPLPGRVGIATQSGAYGAHLLGMARQRRLGTPICVA 203

Query: 182 VGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKK-KPVIALKAGKS 240
            GN AD+   + + +L ++ E   +  Y E IRN   F+   +   +  KPVI  K G+S
Sbjct: 204 TGNEADVTLGDSIGWLVESPEIDVVMAYAESIRNVDSFLAALEAAHRAGKPVILHKVGRS 263

Query: 241 ESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQPL-PRGKRVAIM 299
             G+RAA SHT SLAG  K+ +A      V+ A T +E++ +A   T+ + P G  + ++
Sbjct: 264 ALGSRAALSHTASLAGDDKVLDAVLGDYAVIRARTTEELMDIAYLATRRIYPVGNSLGMI 323

Query: 300 TNAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASA 351
           T +GG G++ +D  ++ GL +  + +   E L++ L   A+  NPVD  A A
Sbjct: 324 TVSGGAGIIVSDVAEEVGLPMPPMPDMAQERLKARL-SFASPINPVDCTAQA 374


>pir||T35878 hypothetical protein SC9B10.09 - Streptomyces coelicolor
           >gi|2661695|emb|CAA15799.1| (AL009204) hypothetical
           protein SC9B10.09 [Streptomyces coelicolor A3(2)]
           Length = 1039
           
 Score =  193 bits (486), Expect = 3e-48
 Identities = 126/417 (30%), Positives = 202/417 (48%), Gaps = 37/417 (8%)

Query: 8   PKGIAVIGASNDPKKLGYEVFKNLKQYK-GGNVYPVNVR----EEEVQGVKAYKSVKDIP 62
           P  +AV+GA   P  +G  +  N++     G +Y VN       +E+ GV A +SV DI 
Sbjct: 212 PGSVAVVGAGRTPGGVGRSILGNIRDAGYTGRLYAVNRAFPEDMKELDGVPACRSVGDID 271

Query: 63  GEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRYGM 122
           G VDLA++ VP + V D +  CGE GV+G+V+I+AG+ ++G EG++ ++ LV  A  YGM
Sbjct: 272 GPVDLAVVTVPAEHVPDVVTACGEHGVQGLVVISAGYADSGPEGRERQRALVRHARTYGM 331

Query: 123 RIIGPNCVGIMNTHAD--LNATFI-TVAKKGNVAFISQSGALGAGIVYKTIKED------ 173
           RIIGPN  GI+NT  D  LNA+    + + G +   +QSGA+G  ++ +  +        
Sbjct: 332 RIIGPNAFGIINTSPDVRLNASLAPEMPRAGRIGLFAQSGAIGIALLSRLHRRGGGVTGV 391

Query: 174 IGFSKFISVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVI 233
            G S F+S GN AD+   ++++Y  D  +     +Y+E I N RKF  +A+R    KP++
Sbjct: 392 TGVSTFVSSGNRADVSGNDVLQYWYDDPQTDVALMYLESIGNPRKFTRLARRTAAAKPLV 451

Query: 234 ALKAGKSESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFT-QPLPR 292
            ++ G    G         +         A  +Q+GV+  +TI +++        QPLP 
Sbjct: 452 VVQ-GARHGGVAPQGHAVRATRLPHATVSALLRQAGVIRVDTITDLVDAGLLLARQPLPA 510

Query: 293 GKRVAIMTNAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASAR 352
           G RVAI+ N+   G+LT D     GL+                      + P+D+  +A 
Sbjct: 511 GPRVAILGNSESLGLLTYDACLSEGLR---------------------PQPPLDLTTAAS 549

Query: 353 GEDYYRTAKLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPVLAM 409
            +D++      L D   D ++   +     G          +R+       KPVL +
Sbjct: 550 ADDFHAALARALADDTCDAVVVTAIPTLGEGAAGDAALAEALRSAAAAVPTKPVLVV 606


>gb|AAG19369.1| (AE005031) acetyl-CoA synthetase; Acs3 [Halobacterium sp. NRC-1]
           Length = 542
           
 Score =  189 bits (475), Expect = 6e-47
 Identities = 109/294 (37%), Positives = 166/294 (56%), Gaps = 5/294 (1%)

Query: 155 ISQSGALGAGIVYKTIKEDIGFSKFISVGNMADLDFAELMEYLADTEEDKAIALYIEGIR 214
           +SQSGA    ++     + IGF    S+GN A L   + M+  AD  +   I  Y+EG+ 
Sbjct: 1   MSQSGAFITAVLDWANDQGIGFKDIASLGNKAVLSETDFMQAWADDPDTNVILGYLEGVD 60

Query: 215 NGRKFIEVAKRVTKKKPVIALKAGKSESGARAASSHTGSLAGSWKIYEAAFKQSGVLVAN 274
           +GR+FI+ A+ VT+  P + +K+G++E+GA+AASSHTG++AGS   YEA FKQ+GV+ A 
Sbjct: 61  DGREFIDDAREVTQDTPAVVVKSGRTEAGAQAASSHTGTIAGSEAAYEAGFKQAGVVRAE 120

Query: 275 TIDEMLSMARAFT-QPLPRGKRVAIMTNAGGPGVLTADELDKRGLKLANLEEKTIEELRS 333
            + E+   ARA    P+P  + VA++TNAGGPGV+  D +    L +A+ E+ TI+ L+ 
Sbjct: 121 NVQELFDFARALDGLPMPDSEDVAVITNAGGPGVMATDAVGDSRLSMASFEDDTIDALQG 180

Query: 334 FLPPMAAVKNPVDMIASARGEDYYRTAKLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGI 393
            +P  A V NPVD+I  A  + +      +L D +V   + +         T      G+
Sbjct: 181 SMPDEANVYNPVDVIGDAEIDRFRTAIDTVLADEHVGCALVLSAPTAVIDYT---ELSGV 237

Query: 394 IRAIKEVNNGKPVLAMFMAGYVSEKAKELLEKNGIPTYERPEDVASAAYALVEQ 447
           I A++E +N KPV+   M G  +E+A ++L   GIP Y  P     +  AL  Q
Sbjct: 238 ITALQEKHN-KPVVTCLMGGERTEQATDVLGDAGIPNYFDPARAIGSLDALAVQ 290


>pir||H83024 hypothetical protein PA4978 [imported] - Pseudomonas aeruginosa
           (strain PAO1) >gi|9951261|gb|AAG08363.1|AE004910_10
           (AE004910) hypothetical protein [Pseudomonas aeruginosa]
           Length = 696
           
 Score =  159 bits (398), Expect = 6e-38
 Identities = 108/326 (33%), Positives = 164/326 (50%), Gaps = 15/326 (4%)

Query: 37  GNVYPVNVREEEVQGVKAYKSVKDIPGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIIT 96
           G ++ VN +  E++GV    SV D+P   D A +   ++   D +     KG  G +   
Sbjct: 37  GQLWLVNPQHAELEGVPCVASVADLPCGPDAAFVATNRELTLDAVAALAAKGAGGAICYA 96

Query: 97  AGFGETGEEGKKEEKELVEIAHRYGMRIIGPNCVGIMN-THADLNATFITVAKKG----- 150
           +GF ETGE+G   ++ L+  A    M ++GPNC G+++  H    A    VA  G     
Sbjct: 97  SGFAETGEQGLAVQRRLLAAAGE--MALLGPNCYGLLDYLH---GAALWPVAHGGRQVER 151

Query: 151 NVAFISQSGALGAGIVYKTIKEDIGFSKFISVGNMADLDFAELMEYLADTEEDKAIALYI 210
            VA ++QSG     +        + +    SVGN A L  AELM+ L D     AI L++
Sbjct: 152 GVAVLTQSGNFAYNLSMSDRSLPVAY--MASVGNQAQLGIAELMDVLLDEPRVTAIGLHL 209

Query: 211 EGIRNGRKFIEVA-KRVTKKKPVIALKAGKSESGARAASSHTGSLAGSWKIYEAAFKQSG 269
           EG++N   F   A K + K  PVIALK G S+ GA  A SHT SLAGS  +Y++ F++ G
Sbjct: 210 EGLKNVPGFARAAYKALQKGVPVIALKTGVSKIGAALALSHTSSLAGSDALYDSLFERLG 269

Query: 270 VL-VANTIDEMLSMARAFTQPLPRGKRVAIMTNAGGPGVLTADELDKRGLKLANLEEKTI 328
           V+ V+  +  + ++  A    LP G  +  +  +GG   L AD  ++ GL L + +    
Sbjct: 270 VIRVSGPVSFVETLKAAACGHLPGGPSLVALACSGGDAGLIADYAERNGLGLPSFDAGQR 329

Query: 329 EELRSFLPPMAAVKNPVDMIASARGE 354
           +EL   LP  A + NP+D   +  G+
Sbjct: 330 DELAGVLPDYANIANPLDFTTAIWGD 355


>pir||A72707 probable succinyl-CoA synthetase alpha chain APE1072 - Aeropyrum
           pernix (strain K1) >gi|5104742|dbj|BAA80057.1|
           (AP000060) 297aa long hypothetical succinyl-CoA
           synthetase alpha chain [Aeropyrum pernix]
           Length = 297
           
 Score = 88.5 bits (216), Expect = 1e-16
 Identities = 78/272 (28%), Positives = 126/272 (45%), Gaps = 27/272 (9%)

Query: 24  GYEVFKNLKQYKGGNVYPVNVREEEVQGVKAYKSVKDIPGE---VDLAIIVVPKKFVKDT 80
           G +V   +   KGG+         EV GV  Y SVK+   E   ++ +I+ VP  F  D 
Sbjct: 37  GTKVVAGVTPGKGGS---------EVHGVPVYDSVKEALAEHPEINTSIVFVPAPFAPDA 87

Query: 81  LIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRYGMRIIGPNCVGIMNT-HADL 139
           + +  + G++ VV+IT G          +    V  A + G  IIGPNC G +    A +
Sbjct: 88  VYEAVDAGIRLVVVITEGIPV------HDTMRFVNYARQKGATIIGPNCPGAITPGQAKV 141

Query: 140 NATFITVAKKGNVAFISQSGALGAGIVYKTIKEDIGFSKFISVGN--MADLDFAELMEYL 197
                 + K+G VA +S+SG L   I Y   ++ IG S  I +G   +  L F E ++  
Sbjct: 142 GIMPGHIFKEGGVAVVSRSGTLTYEISYMLTRQGIGQSTVIGIGGDPIVGLSFTEALKLF 201

Query: 198 ADTEEDKAIALYIE-GIRNGRKFIEVAKRVTKKKPVIALKAGKSESGARAASSHTGSL-- 254
            +  + +A+ L  E G     +  E+ K+    KPVIA  AG++ +       H G++  
Sbjct: 202 QEDPQTEALVLIGEIGGDMEERAAEMIKKGEFTKPVIAYIAGRT-APPEKRMGHAGAIIM 260

Query: 255 --AGSWKIYEAAFKQSGVLVANTIDEMLSMAR 284
              G+++    A +++GV VA T  E+  + R
Sbjct: 261 MGTGTYEGKVKALREAGVEVAETPFEVPELVR 292


>gi|11499767 succinyl-CoA synthetase, alpha subunit (sucD-2) [Archaeoglobus
           fulgidus] >gi|6647837|sp|O28098|SUD2_ARCFU SUCCINYL-COA
           SYNTHETASE ALPHA CHAIN 2 (SCS-ALPHA 2)
           >gi|7437885|pir||A69523 succinate--CoA ligase
           (ADP-forming) (EC 6.2.1.5) alpha-2 chain - Archaeoglobus
           fulgidus >gi|2648340|gb|AAB89067.1| (AE000954)
           succinyl-CoA synthetase, alpha subunit (sucD-2)
           [Archaeoglobus fulgidus]
           Length = 287
           
 Score = 85.0 bits (207), Expect = 2e-15
 Identities = 72/247 (29%), Positives = 114/247 (46%), Gaps = 23/247 (9%)

Query: 48  EVQGVKAYKSVKDIPGEVDL--AIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEE 105
           EV GV  Y SVK+   E D   ++I VP  F  D +++  + G+K +V IT G       
Sbjct: 47  EVLGVPVYDSVKEAVREADANASVIFVPAPFAADAVMEAADAGIKVIVCITEGIPV---- 102

Query: 106 GKKEEKELVEIAHRYGMRIIGPNCVGIMN---THADLNATFITVAKKGNVAFISQSGALG 162
              +E ++       G  +IGPNC GI++   TH  L    + + K GNV  +S+SG L 
Sbjct: 103 --HDELKMYWRVKEAGATLIGPNCPGIISPGKTH--LGIMPVQIFKPGNVGIVSRSGTLT 158

Query: 163 AGIVYKTIKEDIGFSKFISVG--NMADLDFAELMEYLADTEEDKAIALYIE-GIRNGRKF 219
             I Y   K  +G S  + +G   +   DF E++    D +E KA+ L  E G R+    
Sbjct: 159 YQIAYNLTKLGLGQSTVVGIGGDRIIGTDFVEVLRLFEDDKETKAVVLVGEIGGRDEEVA 218

Query: 220 IEVAKRVTKKKPVIALKAGKSESGARAASSHTGSL----AGSWKIYEAAFKQSGVLVANT 275
            E  + ++  KPV+   AG +    +    H G++     G+ +    A + +G  V  T
Sbjct: 219 AEFIREMS--KPVVGYVAGLTAPPGK-RMGHAGAIIEGGVGTAESKIKALEAAGARVGKT 275

Query: 276 IDEMLSM 282
             E+  +
Sbjct: 276 PMEVAEL 282


>sp|Q58643|SUCD_METJA SUCCINYL-COA SYNTHETASE ALPHA CHAIN (SCS-ALPHA)
           >gi|2118349|pir||E64455 succinate--CoA ligase
           (ADP-forming) (EC 6.2.1.5) alpha chain - Methanococcus
           jannaschii >gi|1591879|gb|AAB99250.1| (U67565)
           succinyl-CoA synthetase, alpha subunit (sucD)
           [Methanococcus jannaschii]
           Length = 294
           
 Score = 82.3 bits (200), Expect = 1e-14
 Identities = 69/243 (28%), Positives = 115/243 (46%), Gaps = 19/243 (7%)

Query: 47  EEVQGVKAYKSVKDIPGEVDL--AIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGE 104
           + V GV  + +VK+   E D   ++I VP  F KD + +  + G++ +V+IT        
Sbjct: 51  QNVHGVPVFDTVKEAVKETDANASVIFVPAPFAKDAVFEAIDAGIELIVVITEHIPV--- 107

Query: 105 EGKKEEKELVEIAHRYGMRIIGPNCVGIMNTHAD-LNATFITVAKKGNVAFISQSGALGA 163
               +  E V  A   G++IIGPN  GI +     L    + V K+G+V  +S+SG L  
Sbjct: 108 ---HDTMEFVNYAEDVGVKIIGPNTPGIASPKVGKLGIIPMEVLKEGSVGMVSRSGTLTY 164

Query: 164 GIVYKTIKEDIGFSKFISVGN--MADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIE 221
            I ++  K   G S  + +G   +  L + E+++     +E +AI +   G   G    E
Sbjct: 165 EIAHQIKKAGFGVSTCVGIGGDPIVGLRYKEVLDLFEKDDETEAIVMI--GEIGGGAEEE 222

Query: 222 VAKRVTK-KKPVIALKAGKSESGARAASSHTGSLA----GSWKIYEAAFKQSGVLVANTI 276
            AK + K KKPVI   AG+S    +    H G++     G+ +    A +++G  VA  I
Sbjct: 223 AAKFIEKMKKPVIGYIAGQSAPEGK-RMGHAGAIVEKGKGTAESKMKALEEAGAYVAKNI 281

Query: 277 DEM 279
            ++
Sbjct: 282 SDI 284


>gb|AAK42618.1| Succinyl-CoA synthetase, alpha subunit (sucD) [Sulfolobus
           solfataricus]
           Length = 260
           
 Score = 81.9 bits (199), Expect = 1e-14
 Identities = 73/266 (27%), Positives = 117/266 (43%), Gaps = 30/266 (11%)

Query: 22  KLGYEVFKNLKQYKGGNVYPVNVREEEVQGVKAYKSVKDI--PGEVDLAIIVVPKKFVKD 79
           K G ++   +   KGG          +V  V  Y +VKD     E D +II VP ++  D
Sbjct: 3   KYGTKIVAGVTPGKGGT---------QVNSVPVYDTVKDAMKEHEADASIIFVPARYAVD 53

Query: 80  TLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRYGMRIIGPNCVGIMNTHADL 139
            + +  + G+K +V IT            +    ++ A   G RIIGPNC GI+     L
Sbjct: 54  AIYEAVDAGIKLIVTITEHIPVL------DMARAIKYARARGARIIGPNCPGIIAPEESL 107

Query: 140 NATFITVA-KKGNVAFISQSGALGAGIVYKTIKEDIGFSKFISVG-----NMADLDFAEL 193
                  A KKG +  +S+SG L   +        +G S  I +G       + L+ A++
Sbjct: 108 VGILPARAFKKGKIGIVSRSGTLTYEVSELLKNSGMGQSTVIGIGGDPIIGTSTLEVAKM 167

Query: 194 MEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKAGKSESGARAASSHTGS 253
            +   D E +K + +   G     +  E  KR   KKP+IA  AG + +       H G+
Sbjct: 168 FD--QDPETEKIVVIGEIGGTMEERLAEAYKRGEIKKPIIAYIAGMT-APREKRMGHAGA 224

Query: 254 LA----GSWKIYEAAFKQSGVLVANT 275
           +     G+++    AFK++G+ +ANT
Sbjct: 225 VVYMGMGTFESKIRAFKEAGIPIANT 250


>gb|AAA27504.2| (M35832) succinyl-CoA synthetase alpha-subunit [Thermus aquaticus]
           Length = 288
           
 Score = 78.8 bits (191), Expect = 1e-13
 Identities = 71/248 (28%), Positives = 112/248 (44%), Gaps = 20/248 (8%)

Query: 48  EVQGVKAYKSVKDIPG--EVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEE 105
           EV GV  Y +VK+     EVD +II VP     D  ++    G+  +V+IT G       
Sbjct: 46  EVLGVPVYDTVKEAVAHHEVDASIIFVPAPAAADAALEAAHAGIPLIVLITEGIPTL--- 102

Query: 106 GKKEEKELVEIAHRYGMRIIGPNCVGIMNTH-ADLNATFITVAKKGNVAFISQSGALGAG 164
              +    VE     G R+IG NC GI++ H   +      V K+G V  IS+SG L   
Sbjct: 103 ---DMVRAVEEIKALGSRLIGGNCPGIISAHLPKIGIMPGHVFKRGRVGIISRSGTLRHE 159

Query: 165 IVYKTIKEDIGFSKFISVGN--MADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEV 222
                 +  +G +  + +G   +  L F +L+    +  E +A+ L   G   G    E 
Sbjct: 160 AAAALSQAGLGTTTTVGIGGDPVRRLTFKDLLPLFNEDPETEAVVLI--GEIGGSDEEEA 217

Query: 223 AKRVT--KKKPVIALKAGKSESGARAASSHTGSL----AGSWKIYEAAFKQSGVLVANTI 276
           A  V    KKPV+    G+S    +    H G++     G+ +    AF ++G+ VA+TI
Sbjct: 218 AAWVKDHMKKPVVGFIGGRSAPKGK-RMGHAGAIIMGNVGTPESKLRAFAEAGIPVADTI 276

Query: 277 DEMLSMAR 284
           DE++ + +
Sbjct: 277 DEIVELVK 284


>gi|11499134 succinyl-CoA synthetase, alpha subunit (sucD-1) [Archaeoglobus
           fulgidus] >gi|6647839|sp|O28733|SUD1_ARCFU SUCCINYL-COA
           SYNTHETASE ALPHA CHAIN 1 (SCS-ALPHA 1)
           >gi|7437884|pir||B69442 succinate--CoA ligase
           (ADP-forming) (EC 6.2.1.5) alpha-1 chain - Archaeoglobus
           fulgidus >gi|2649022|gb|AAB89707.1| (AE000996)
           succinyl-CoA synthetase, alpha subunit (sucD-1)
           [Archaeoglobus fulgidus]
           Length = 291
           
 Score = 77.6 bits (188), Expect = 3e-13
 Identities = 76/289 (26%), Positives = 133/289 (45%), Gaps = 31/289 (10%)

Query: 9   KGIAVIGASNDPKKL---GYEVFKNLKQYKGGNVYPVNVREEEVQGVKAYKSVKDIPGEV 65
           +GI     S   K++   G +V   +   KGG+         EV G+  Y +V++   E 
Sbjct: 17  QGITGFQGSFQAKRMLDYGTKVVGGVTPGKGGS---------EVHGIPVYNTVEEAVAET 67

Query: 66  --DLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRYGMR 123
             D +II VP +F  D + +  + G++ VV +T G     E      ++L E+       
Sbjct: 68  NADTSIIYVPARFATDAIFEAFDAGLRLVVCVTEGIPLYDE--MLIHRKLREVKSM---- 121

Query: 124 IIGPNCVGIMNT-HADLNATFITVAKKGNVAFISQSGALGAGIVYKTIKEDIGFSKFISV 182
           ++GPNC G+++   + +         +GN+  +S+SG L   I     K  IG S  + +
Sbjct: 122 LLGPNCPGVISPGRSKVGLLPDRSFTQGNLGVVSRSGTLTYQICENLTKAGIGQSTVVGI 181

Query: 183 GN--MADLDFAELMEYLADTEEDKAIALYIE-GIRNGRKFIEVAKRVTKKKPVIALKAGK 239
           G   M  L F ++++   + EE KA+ L  E G     K  E  K+++  KPV+A  AG+
Sbjct: 182 GGDPMPGLTFVDVLKMFEEDEETKAVLLVGEIGGTAEEKAAEFIKQMS--KPVVAFIAGR 239

Query: 240 SESGARAASSHTGSL----AGSWKIYEAAFKQSGVLVANTIDEMLSMAR 284
           +    +    H G++     G+ +   AA + +G  VA T+ +++   R
Sbjct: 240 TAPPGK-RMGHAGAIIEGSTGTAEAKMAALRDAGARVAETLLDVVKEVR 287


>pir||F81399 succinate--CoA ligase (ADP-forming) (EC 6.2.1.5) alpha chain Cj0534
           [imported] - Campylobacter jejuni (strain NCTC 11168)
           >gi|6968002|emb|CAB75170.1| (AL139075) succinyl-coA
           synthetase alpha chain [Campylobacter jejuni]
           Length = 289
           
 Score = 77.6 bits (188), Expect = 3e-13
 Identities = 71/251 (28%), Positives = 115/251 (45%), Gaps = 23/251 (9%)

Query: 24  GYEVFKNLKQYKGGNVYPVN-VREEEVQGVKAYKSVKDIPGEVDLAIIVVPKKFVKDTLI 82
           G  +   +  +KGG  +    V +     VKA K+        D+++I VP   V D++I
Sbjct: 32  GTNIVGGITPHKGGQTHLGKPVFDTVADAVKATKA--------DVSLIFVPAFAVGDSVI 83

Query: 83  QCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRYGMRIIGPNCVGIMNT-HADLNA 141
           +  + G+K  V+IT           K+     + A++ GM+IIGPNC GI+ +    L  
Sbjct: 84  EAADAGIKLAVVITE------HTPVKDMMFAKQYANKKGMKIIGPNCPGIITSEECKLGI 137

Query: 142 TFITVAKKGNVAFISQSGALGAGIVYKTIKEDIGFSKFISVGN--MADLDFAELMEYLAD 199
               + KKG V  IS+SG L      + ++   G S  + +G   +  L + EL+     
Sbjct: 138 MPGFIFKKGCVGLISKSGTLTYEAANQVVQGGYGISTAVGIGGDPIIGLAYKELLSEFQK 197

Query: 200 TEEDKAIALYIEGIRNGRKFIEVAKRVTK--KKPVIALKAGKSESGARAASSHTGSLAGS 257
            +E KAI +   G   G   +E AK + +   KPV+A  AG +    +    H G++ GS
Sbjct: 198 DDETKAIVMI--GEIGGSLEVEAAKFIKENISKPVVAFIAGATAPKGK-RMGHAGAIVGS 254

Query: 258 WKIYEAAFKQS 268
                AA K++
Sbjct: 255 ADESAAAKKEA 265


>emb|CAB92672.1| (AL356832) succinyl CoA synthetase alpha chain [Streptomyces
           coelicolor A3(2)]
           Length = 294
           
 Score = 74.9 bits (181), Expect = 2e-12
 Identities = 80/292 (27%), Positives = 125/292 (42%), Gaps = 49/292 (16%)

Query: 10  GIAVIGASNDPKKLGYEVFKNLKQYKGGNVYPVNVREEEVQGVKAYKSVKDIPGEVDLAI 69
           G  V+G  N P+K G  V      + G  V      +E ++   A           ++++
Sbjct: 32  GTEVVGGVN-PRKAGTSV-----DFDGNEVPVFGTVKEAIEKTGA-----------NVSV 74

Query: 70  IVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGE------EGKKEEKELVEIAHRYGMR 123
           I VP+KF KD +++  +  +   V+IT G             GKK  K           R
Sbjct: 75  IFVPEKFTKDAVVEAIDAEIPLAVVITEGIAVHDSAAFWSYAGKKGNK----------TR 124

Query: 124 IIGPNCVGIMNTHADLNATFI--TVAKKGNVAFISQSGALGAGIVYKTIKEDIGFSKFIS 181
           IIGPNC GI+ T    N   I   + K G +  +S+SG L   ++Y+    DIGFS  + 
Sbjct: 125 IIGPNCPGII-TPGQSNVGIIPGDITKPGRIGLVSKSGTLTYQMMYEL--RDIGFSTAVG 181

Query: 182 VGN---MADLDFAELMEYLADTEEDKAIAL-YIEGIRNGRKFIEVAKRVTKKKPVIALKA 237
           +G    +       L  + AD E D  + +  I G    R    ++K VT  KPV+   A
Sbjct: 182 IGGDPIIGTTHIDALAAFEADPETDLIVMIGEIGGDAEERAAEYISKNVT--KPVVGYVA 239

Query: 238 GKSESGARAASSHTGSL----AGSWKIYEAAFKQSGVLVANTIDEMLSMARA 285
           G +    +    H G++    +G+ +  + A + +GV V  T  E   +ARA
Sbjct: 240 GFTAPEGK-TMGHAGAIVSGSSGTAQAKKEALEAAGVKVGKTPTETAKLARA 290


>sp|P09143|SUCD_THEFL SUCCINYL-COA SYNTHETASE ALPHA CHAIN (SCS-ALPHA)
           >gi|68575|pir||SYTWSA succinate--CoA ligase
           (ADP-forming) (EC 6.2.1.5) alpha chain [validated] -
           Thermus aquaticus >gi|48178|emb|CAA38007.1| (X54073)
           succinate--CoA ligase (ADP-forming) [Thermus aquaticus
           flavus] >gi|581794|emb|CAA39507.1| (X56033) succinyl-CoA
           synthetase [Thermus aquaticus]
           >gi|581798|emb|CAA31303.1| (X12815) succinyl-CoA
           synthetase alpha-subunit (AA 1-288) [Thermus aquaticus]
           >gi|227823|prf||1712304D succinyl CoA
           synthetase:SUBUNIT=alpha [Thermus aquaticus flavus]
           Length = 288
           
 Score = 74.5 bits (180), Expect = 2e-12
 Identities = 69/248 (27%), Positives = 110/248 (43%), Gaps = 20/248 (8%)

Query: 48  EVQGVKAYKSVKDIPG--EVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEE 105
           EV GV  Y +VK+     EVD +II VP     D  ++    G+  +V+IT G       
Sbjct: 46  EVLGVPVYDTVKEAVAHHEVDASIIFVPAPAAADAALEAAHAGIPLIVLITEGIPTL--- 102

Query: 106 GKKEEKELVEIAHRYGMRIIGPNCVGIMNT-HADLNATFITVAKKGNVAFISQSGALGAG 164
              +    VE     G R+IG NC GI++     +      V K+G V  IS+SG L   
Sbjct: 103 ---DMVRAVEEIKALGSRLIGGNCPGIISAEETKIGIMPGHVFKRGRVGIISRSGTLTYE 159

Query: 165 IVYKTIKEDIGFSKFISVGN--MADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEV 222
                 +  +G +  + +G   +    F +L+    +  E +A+ L   G   G    E 
Sbjct: 160 AAAALSQAGLGTTTTVGIGGDPVIGTTFKDLLPLFNEDPETEAVVLI--GEIGGSDEEEA 217

Query: 223 AKRVT--KKKPVIALKAGKSESGARAASSHTGSL----AGSWKIYEAAFKQSGVLVANTI 276
           A  V    KKPV+    G+S    +    H G++     G+ +    AF ++G+ VA+TI
Sbjct: 218 AAWVKDHMKKPVVGFIGGRSAPKGK-RMGHAGAIIMGNVGTPESKLRAFAEAGIPVADTI 276

Query: 277 DEMLSMAR 284
           DE++ + +
Sbjct: 277 DEIVELVK 284


>prf||1708208A succinyl CoA synthetase [Thermus aquaticus]
           Length = 288
           
 Score = 74.5 bits (180), Expect = 2e-12
 Identities = 69/248 (27%), Positives = 110/248 (43%), Gaps = 20/248 (8%)

Query: 48  EVQGVKAYKSVKDIPG--EVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEE 105
           EV GV  Y +VK+     EVD +II VP     D  ++    G+  +V+IT G       
Sbjct: 46  EVLGVPVYDTVKEAVAHHEVDASIIFVPAPAAADAALEAAHAGIPLIVLITEGIPTL--- 102

Query: 106 GKKEEKELVEIAHRYGMRIIGPNCVGIMNT-HADLNATFITVAKKGNVAFISQSGALGAG 164
              +    VE     G R+IG NC GI++     +      V K+G V  IS+SG L   
Sbjct: 103 ---DMVRAVEEIKALGSRLIGGNCPGIISAEETKIGIMPGHVFKRGRVGIISRSGTLTYE 159

Query: 165 IVYKTIKEDIGFSKFISVGN--MADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEV 222
                 +  +G +  + +G   +    F +L+    +  E +A+ L   G   G    E 
Sbjct: 160 AAAALSQAGLGTTTTVGIGGDPVIGTTFKDLLPLFNEDPETEAVVLI--GEIGGSDEEEA 217

Query: 223 AKRVT--KKKPVIALKAGKSESGARAASSHTGSL----AGSWKIYEAAFKQSGVLVANTI 276
           A  V    KKPV+    G+S    +    H G++     G+ +    AF ++G+ VA+TI
Sbjct: 218 AAWVKDHMKKPVVGFIGGRSAPKGK-RMGHAGAIIMGNVGTPESKLRAFAEAGIPVADTI 276

Query: 277 DEMLSMAR 284
           DE++ + +
Sbjct: 277 DEIVELVK 284


>prf||1414360A succinyl-CoA synthetase alpha [Thermus aquaticus]
           Length = 288
           
 Score = 73.4 bits (177), Expect = 5e-12
 Identities = 69/248 (27%), Positives = 110/248 (43%), Gaps = 20/248 (8%)

Query: 48  EVQGVKAYKSVKDIPG--EVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEE 105
           EV GV  Y +VK+     EVD +II VP     D  ++    G+  +V+IT G       
Sbjct: 46  EVLGVPVYDTVKEAVAHHEVDASIIFVPAPAAADAALEAAHAGIPLIVLITEGIPTL--- 102

Query: 106 GKKEEKELVEIAHRYGMRIIGPNCVGIMNT-HADLNATFITVAKKGNVAFISQSGALGAG 164
              +    VE     G R+IG NC GI++     +      V K+G V  IS+SG L   
Sbjct: 103 ---DMVRAVEEIKALGSRLIGGNCPGIISAEETKIGIMPGHVFKRGRVGIISRSGTLTYE 159

Query: 165 IVYKTIKEDIGFSKFISVGN--MADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEV 222
                 +  +G +  + +G   +    F +L+    +  E +A+ L   G   G    E 
Sbjct: 160 AAAALSQAGLGTTTTVGIGGDPVITGTFKDLLPLFNEDPETEAVVLI--GEIGGSDEEEA 217

Query: 223 AKRVT--KKKPVIALKAGKSESGARAASSHTGSL----AGSWKIYEAAFKQSGVLVANTI 276
           A  V    KKPV+    G+S    +    H G++     G+ +    AF ++G+ VA+TI
Sbjct: 218 AAWVKDHMKKPVVGFIGGRSAPKGK-RMGHAGAIIMGNVGTPESKLRAFAEAGIPVADTI 276

Query: 277 DEMLSMAR 284
           DE++ + +
Sbjct: 277 DEIVELVK 284


>pir||F81180 conserved hypothetical protein NMB0593 [imported] - Neisseria
           meningitidis (group B strain MD58)
           >gi|7225823|gb|AAF41021.1| (AE002415) conserved
           hypothetical protein [Neisseria meningitidis MC58]
           Length = 808
           
 Score = 72.2 bits (174), Expect = 1e-11
 Identities = 74/302 (24%), Positives = 124/302 (40%), Gaps = 20/302 (6%)

Query: 4   YFFNPKGIAVIGASNDPKKLGYEVFKNLKQYK-GGNVYPVNVREEEVQGVKAYKSVKDIP 62
           YFF P  I +IGAS  P  LG  V  NL      G + PVN R   + G+ AY S+  IP
Sbjct: 9   YFFMPNHIILIGASEQPYSLGERVLSNLLSTPFQGKITPVNPRHHTIAGLPAYTSLNKIP 68

Query: 63  GEVDLAI-IVVPKKFVKDTLIQ-CGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRY 120
           G  DL I + +P  +  DTL + C +K ++ +++I      +  E    E   +   H  
Sbjct: 69  GNADLIIAVTLPDSY--DTLFKTCRKKQLRHIILIQDWDNLSAAELHTAE-TAIRKHHGN 125

Query: 121 GMRIIGPNCVGIMNTHADLNATFITVAKKGNVAFISQSGALGAGIVYKTIKEDIGFSKFI 180
           G+ I      GI      LN +       G+ A ++ + A+   I     K   G S+ I
Sbjct: 126 GLNITACTTAGIQLPSLGLNISTQDGYAAGHTAILTGNAAVSRQIDNILNKLRQGTSRHI 185

Query: 181 SV-GNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKAGK 239
           S+   ++ +  A+ +     +   K   L+     + RK     ++ T+  P+I     +
Sbjct: 186 SLHPGISPITSADWLNRFGHSLHTKTAVLHHNPEEDQRKLFSAIRQFTRHTPLILHITCR 245

Query: 240 SESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQPLPRGKRVAIM 299
           +    RA             +     +    LV+   D++ +  RA    LP   R+ I+
Sbjct: 246 TTETDRA-------------VLHCLARHCNFLVSFNADDLEAALRAQLSDLPPLSRLDIL 292

Query: 300 TN 301
           ++
Sbjct: 293 SD 294


>pir||D81924 hypothetical protein NMA0796 [imported] - Neisseria meningitidis
           (group A strain Z2491) >gi|7379516|emb|CAB84079.1|
           (AL162754) hypothetical protein NMA0796 [Neisseria
           meningitidis Z2491]
           Length = 808
           
 Score = 70.2 bits (169), Expect = 4e-11
 Identities = 73/302 (24%), Positives = 123/302 (40%), Gaps = 20/302 (6%)

Query: 4   YFFNPKGIAVIGASNDPKKLGYEVFKNLKQYK-GGNVYPVNVREEEVQGVKAYKSVKDIP 62
           YFF P  I +IGAS  P  LG  V  NL      G + PVN R   + G+ AY S+  IP
Sbjct: 9   YFFMPNHIILIGASERPYSLGERVLSNLLSTPFQGKITPVNPRHHTIAGLPAYTSLNKIP 68

Query: 63  GEVDLAI-IVVPKKFVKDTLIQ-CGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRY 120
           G  DL I + +P  +  DTL + C +K ++ +++I         E    E   +   H  
Sbjct: 69  GNADLIIAVTLPDSY--DTLFKTCRKKQLRHIILIQDWDSLPAAELHTAE-TAIRKHHGN 125

Query: 121 GMRIIGPNCVGIMNTHADLNATFITVAKKGNVAFISQSGALGAGIVYKTIKEDIGFSKFI 180
           G+ I      GI      LN +       G+ A ++ + A+   I     K   G S+ I
Sbjct: 126 GLNITACTTAGIQLPSLGLNISTQDGYAAGHTAILTGNAAVSRQIDNILNKLRQGTSRHI 185

Query: 181 SV-GNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKAGK 239
           S+   ++ +  A+ +     +   K   L+     + RK     ++ T+  P+I     +
Sbjct: 186 SLHPGISPITSADWLNRFGHSLHTKTAVLHHNPEEDQRKLFSAIRQFTRHTPLILHITCR 245

Query: 240 SESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQPLPRGKRVAIM 299
           +    RA             +     +    L++   D++ +  RA    LP   R+ I+
Sbjct: 246 TTETDRA-------------VLHCLARHCNFLISFNADDLEAALRAQLSDLPPLSRLDIL 292

Query: 300 TN 301
           ++
Sbjct: 293 SD 294


>emb|CAC12452.1| (AL445067) probable succinyl-CoA synthetase, alpha subunit
           [Thermoplasma acidophilum]
           Length = 294
           
 Score = 69.9 bits (168), Expect = 6e-11
 Identities = 74/262 (28%), Positives = 119/262 (45%), Gaps = 25/262 (9%)

Query: 22  KLGYEVFKNLKQYKGGNVYPVNVREEEVQGVKAYKSVKD-IPGEVDLAIIVVPKKFVKDT 80
           K G +V   +   KGG  +           V    SV + +  E D  +I VP  +VKD 
Sbjct: 38  KFGTKVVAGIAPGKGGTKF--------ADKVPIVNSVSEAMQYEPDATMISVPAPYVKDA 89

Query: 81  LIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRYGMRIIGPNCVGI-MNTHADL 139
             +  + G+K V I+T           ++  E+V+ A   G+ ++GPN  GI +   + +
Sbjct: 90  AYEAIDNGLKIVYILTE------HVPYQDTMEIVKEASLRGITVLGPNGPGITVPFESKI 143

Query: 140 NATFITVAKKGNVAFISQSGALGAGIVYKTIKEDIGFSKFISVG--NMADLDFAELMEYL 197
                 + K+G+VA  S+SG L   IVY   K  +G S  I +G   +  L F ++++  
Sbjct: 144 GIMPNHIFKEGDVAIASRSGTLTYEIVYAVTKAGMGESTVIGLGGDRVVGLTFIDVLKMF 203

Query: 198 ADTEEDKAIALYIE-GIRNGRKFIEVAKRVTKKKPVIALKAGKSESGARAASSHTGSL-- 254
              E+ K I L  E G  N     +  K+  KKK V+A  AG+S    +    H G++  
Sbjct: 204 EKDEKTKRIVLVGEIGGNNEELAADYIKKHVKKK-VVAYIAGRSAPPGK-RMGHAGAIIE 261

Query: 255 --AGSWKIYEAAFKQSGVLVAN 274
              G+ +    AF ++GV VA+
Sbjct: 262 RGVGTAESKLKAFAEAGVKVAD 283


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.316    0.135    0.375 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 164372560
Number of Sequences: 2977
Number of extensions: 7050553
Number of successful extensions: 20309
Number of sequences better than 1.0e-10: 44
Number of HSP's better than  0.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 20118
Number of HSP's gapped (non-prelim): 47
length of query: 457
length of database: 189,106,746
effective HSP length: 60
effective length of query: 397
effective length of database: 153,197,526
effective search space: 60819417822
effective search space used: 60819417822
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.6 bits)
S2: 166 (69.1 bits)