BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB0854 (PAB0854) DE:Hypothetical protein (457 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||D75038 hypothetical protein PAB0854 - Pyrococcus abyssi (st... 901 0.0 pir||G71124 hypothetical protein PH0766 - Pyrococcus horikoshii ... 866 0.0 pir||T48661 acetate--CoA ligase (ADP-forming) (EC 6.2.1.13) alph... 402 e-111 pir||D75106 hypothetical protein PAB1937 - Pyrococcus abyssi (st... 395 e-109 pir||A71028 hypothetical protein PH1517 - Pyrococcus horikoshii ... 392 e-108 pir||E71189 hypothetical protein PH1789 - Pyrococcus horikoshii ... 388 e-107 pir||E75149 succinyl-coa synthetase alpha chain related protein ... 383 e-105 sp|Q58010|Y590_METJA HYPOTHETICAL PROTEIN MJ0590 >gi|2128020|pir... 383 e-105 pir||A75021 succinyl-coa synthetase alpha chain related protein ... 382 e-105 pir||H71207 hypothetical protein PH1928 - Pyrococcus horikoshii ... 375 e-103 gi|11498810 conserved hypothetical protein [Archaeoglobus fulgid... 369 e-101 pir||F75054 hypothetical protein PAB1431 - Pyrococcus abyssi (st... 365 e-100 pir||H71106 hypothetical protein PH0625 - Pyrococcus horikoshii ... 354 8e-97 gi|11499106 conserved hypothetical protein [Archaeoglobus fulgid... 353 2e-96 emb|CAC12278.1| (AL445066) probable acetyl-CoA synthetase [Therm... 339 5e-92 gb|AAF88064.1|AF286346_1 (AF286346) acetyl-CoA synthetase [Entam... 327 2e-88 gb|AAK42002.1| Conserved hypothetical protein [Sulfolobus solfat... 323 3e-87 gb|AAD44021.1|AF107206_1 (AF107206) acetyl-CoA synthetase [Giard... 309 3e-83 gi|11498792 conserved hypothetical protein [Archaeoglobus fulgid... 301 1e-80 pir||T35770 hypothetical protein SC8A6.03c SC8A6.03c - Streptomy... 295 7e-79 gi|11499522 conserved hypothetical protein [Archaeoglobus fulgid... 279 5e-74 gi|11498537 conserved hypothetical protein [Archaeoglobus fulgid... 279 5e-74 pir||C82443 conserved hypothetical protein VCA0574 [imported] - ... 261 1e-68 dbj|BAA10925.1| (D64044) hypothetycal 67KD protein fragment in U... 234 2e-60 sp|P76594|YFIQ_ECOLI HYPOTHETICAL 98.0 KD PROTEIN IN UNG-PSSA IN... 234 2e-60 emb|CAA10043.1| (AJ012480) pimeloyl-CoA synthetase [Pseudomonas ... 199 5e-50 pir||B83518 pimeloyl-CoA synthetase PA1017 [imported] - Pseudomo... 197 2e-49 pir||T35878 hypothetical protein SC9B10.09 - Streptomyces coelic... 193 3e-48 gb|AAG19369.1| (AE005031) acetyl-CoA synthetase; Acs3 [Halobacte... 189 6e-47 pir||H83024 hypothetical protein PA4978 [imported] - Pseudomonas... 159 6e-38 pir||A72707 probable succinyl-CoA synthetase alpha chain APE1072... 89 1e-16 gi|11499767 succinyl-CoA synthetase, alpha subunit (sucD-2) [Arc... 85 2e-15 sp|Q58643|SUCD_METJA SUCCINYL-COA SYNTHETASE ALPHA CHAIN (SCS-AL... 82 1e-14 gb|AAK42618.1| Succinyl-CoA synthetase, alpha subunit (sucD) [Su... 82 1e-14 gb|AAA27504.2| (M35832) succinyl-CoA synthetase alpha-subunit [T... 79 1e-13 gi|11499134 succinyl-CoA synthetase, alpha subunit (sucD-1) [Arc... 78 3e-13 pir||F81399 succinate--CoA ligase (ADP-forming) (EC 6.2.1.5) alp... 78 3e-13 emb|CAB92672.1| (AL356832) succinyl CoA synthetase alpha chain [... 75 2e-12 sp|P09143|SUCD_THEFL SUCCINYL-COA SYNTHETASE ALPHA CHAIN (SCS-AL... 75 2e-12 prf||1708208A succinyl CoA synthetase [Thermus aquaticus] 75 2e-12 prf||1414360A succinyl-CoA synthetase alpha [Thermus aquaticus] 73 5e-12 pir||F81180 conserved hypothetical protein NMB0593 [imported] - ... 72 1e-11 pir||D81924 hypothetical protein NMA0796 [imported] - Neisseria ... 70 4e-11 emb|CAC12452.1| (AL445067) probable succinyl-CoA synthetase, alp... 70 6e-11 >pir||D75038 hypothetical protein PAB0854 - Pyrococcus abyssi (strain Orsay) >gi|5458714|emb|CAB50201.1| (AJ248287) hypothetical protein [Pyrococcus abyssi] Length = 457 Score = 901 bits (2304), Expect = 0.0 Identities = 457/457 (100%), Positives = 457/457 (100%) Query: 1 MLDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYKGGNVYPVNVREEEVQGVKAYKSVKD 60 MLDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYKGGNVYPVNVREEEVQGVKAYKSVKD Sbjct: 1 MLDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYKGGNVYPVNVREEEVQGVKAYKSVKD 60 Query: 61 IPGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRY 120 IPGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRY Sbjct: 61 IPGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRY 120 Query: 121 GMRIIGPNCVGIMNTHADLNATFITVAKKGNVAFISQSGALGAGIVYKTIKEDIGFSKFI 180 GMRIIGPNCVGIMNTHADLNATFITVAKKGNVAFISQSGALGAGIVYKTIKEDIGFSKFI Sbjct: 121 GMRIIGPNCVGIMNTHADLNATFITVAKKGNVAFISQSGALGAGIVYKTIKEDIGFSKFI 180 Query: 181 SVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKAGKS 240 SVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKAGKS Sbjct: 181 SVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKAGKS 240 Query: 241 ESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQPLPRGKRVAIMT 300 ESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQPLPRGKRVAIMT Sbjct: 241 ESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQPLPRGKRVAIMT 300 Query: 301 NAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARGEDYYRTA 360 NAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARGEDYYRTA Sbjct: 301 NAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARGEDYYRTA 360 Query: 361 KLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPVLAMFMAGYVSEKAK 420 KLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPVLAMFMAGYVSEKAK Sbjct: 361 KLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPVLAMFMAGYVSEKAK 420 Query: 421 ELLEKNGIPTYERPEDVASAAYALVEQAKNVGVLEVE 457 ELLEKNGIPTYERPEDVASAAYALVEQAKNVGVLEVE Sbjct: 421 ELLEKNGIPTYERPEDVASAAYALVEQAKNVGVLEVE 457 >pir||G71124 hypothetical protein PH0766 - Pyrococcus horikoshii >gi|3257174|dbj|BAA29857.1| (AP000003) 457aa long hypothetical protein [Pyrococcus horikoshii] Length = 457 Score = 866 bits (2213), Expect = 0.0 Identities = 433/457 (94%), Positives = 449/457 (97%) Query: 1 MLDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYKGGNVYPVNVREEEVQGVKAYKSVKD 60 MLDYFFNPKGIAVIGASNDPKKLGYEVFKNLK+YK G VYPVN++EEEVQGVKAYKSVKD Sbjct: 1 MLDYFFNPKGIAVIGASNDPKKLGYEVFKNLKEYKKGKVYPVNIKEEEVQGVKAYKSVKD 60 Query: 61 IPGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRY 120 IP E+DLAIIVVPK+FVKDTLIQCGEKGVKGVVIITAGFGETGEEGK+EEKELVEIAH+Y Sbjct: 61 IPDEIDLAIIVVPKRFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKREEKELVEIAHKY 120 Query: 121 GMRIIGPNCVGIMNTHADLNATFITVAKKGNVAFISQSGALGAGIVYKTIKEDIGFSKFI 180 GMRIIGPNCVGIMNTH DLNATFITVAKKGNVAFISQSGALGAGIVYKTIKEDIGFSKFI Sbjct: 121 GMRIIGPNCVGIMNTHVDLNATFITVAKKGNVAFISQSGALGAGIVYKTIKEDIGFSKFI 180 Query: 181 SVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKAGKS 240 SVGNMAD+DFAELMEYLADTEEDKAIALYIEG+RNG+KF+EVAKRVTKKKP+IALKAGKS Sbjct: 181 SVGNMADVDFAELMEYLADTEEDKAIALYIEGVRNGKKFMEVAKRVTKKKPIIALKAGKS 240 Query: 241 ESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQPLPRGKRVAIMT 300 ESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAF+QPLPRG +VAIMT Sbjct: 241 ESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFSQPLPRGNKVAIMT 300 Query: 301 NAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARGEDYYRTA 360 NAGGPGVLTADELDKRGLKLA LEEKTIEELRSFLPPMAAVKNPVDMIASARGEDYYRTA Sbjct: 301 NAGGPGVLTADELDKRGLKLATLEEKTIEELRSFLPPMAAVKNPVDMIASARGEDYYRTA 360 Query: 361 KLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPVLAMFMAGYVSEKAK 420 KLLLQDPNVDMLIAICVVPTFAGMT TEHAEGIIRA+KEVNN KPVLAMFMAGYVSEKAK Sbjct: 361 KLLLQDPNVDMLIAICVVPTFAGMTLTEHAEGIIRAVKEVNNEKPVLAMFMAGYVSEKAK 420 Query: 421 ELLEKNGIPTYERPEDVASAAYALVEQAKNVGVLEVE 457 ELLEKNGIPTYERPEDVASAAYALVEQAKNVG+LEVE Sbjct: 421 ELLEKNGIPTYERPEDVASAAYALVEQAKNVGILEVE 457 >pir||T48661 acetate--CoA ligase (ADP-forming) (EC 6.2.1.13) alpha chain [validated] - Pyrococcus furiosus >gi|5419966|emb|CAB46516.1| (AJ240061) acetyl-CoA synthetase [Pyrococcus furiosus] Length = 462 Score = 402 bits (1022), Expect = e-111 Identities = 228/456 (50%), Positives = 300/456 (65%), Gaps = 12/456 (2%) Query: 2 LDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYK-GGNVYPVNVR--EEEVQG--VKAYK 56 L+ FNPK +AVIGAS P K+GY + KNL +Y G +YPVN++ E E+ G K YK Sbjct: 3 LEALFNPKSVAVIGASAKPGKIGYAIMKNLIEYGYEGKIYPVNIKGGEIEINGRKFKVYK 62 Query: 57 SVKDIPGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEI 116 SV +IP EVD+A+IVVP KFV L +CG+KGVK V II++GFGE GEEGKK E++LVE Sbjct: 63 SVLEIPDEVDMAVIVVPAKFVPQVLEECGQKGVKVVPIISSGFGELGEEGKKVEQQLVET 122 Query: 117 AHRYGMRIIGPNCVGIMNTHADLNATF-ITVAKKGNVAFISQSGALGAGIVYKTIKEDIG 175 A +YGMRI+GPN G++ T A LNATF T G +A ISQSGALG ++ TI E IG Sbjct: 123 ARKYGMRILGPNIFGVVYTPAKLNATFGPTDVLPGPLALISQSGALGIALMGWTILEKIG 182 Query: 176 FSKFISVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIAL 235 S +SVGN AD+D A+L+E+ D E +AI +Y+EG+++GR+F+EVAK V+KKKP+I + Sbjct: 183 LSAVVSVGNKADIDDADLLEFFKDDENTRAILIYMEGVKDGRRFMEVAKEVSKKKPIIVI 242 Query: 236 KAGKSESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQ-PLPRGK 294 KAG+SE GA+AA+SHTGSLAGS K+Y AAFKQSGVL A TI E ARA + P P+G Sbjct: 243 KAGRSERGAKAAASHTGSLAGSDKVYSAAFKQSGVLRAYTIGEAFDWARALSNLPEPQGD 302 Query: 295 RVAIMTNAGGPGVLTADELDKRGLKL-ANLEEKTIEELRSFLPPMAAVKNPVDMIASARG 353 V I+TN GG GV+ D ++ GL L NLEE I + +PP + KNPVD+ A G Sbjct: 303 NVVIITNGGGIGVMATDAAEEEGLHLYDNLEELKI--FANHMPPFGSYKNPVDLTGMADG 360 Query: 354 EDYYRTAKLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPVLAMFMAG 413 + Y + L P + IA+ T A + P E AE +IR E KP++ + G Sbjct: 361 KSYEGAIRDALAHPEMHS-IAVLYCQT-AVLDPRELAEIVIREYNESGRKKPLVVAIVGG 418 Query: 414 YVSEKAKELLEKNGIPTYERPEDVASAAYALVEQAK 449 +++A ++L +NGIP Y PE A AL + +K Sbjct: 419 IEAKEAIDMLNENGIPAYPEPERAIKALSALYKWSK 454 >pir||D75106 hypothetical protein PAB1937 - Pyrococcus abyssi (strain Orsay) >gi|5458076|emb|CAB49565.1| (AJ248285) hypothetical protein [Pyrococcus abyssi] Length = 460 Score = 395 bits (1005), Expect = e-109 Identities = 222/458 (48%), Positives = 297/458 (64%), Gaps = 16/458 (3%) Query: 2 LDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYK-GGNVYPVNVR--EEEVQG--VKAYK 56 L+ FNPK IAVIGAS+ P K+GY + KNL +Y G +YPVN++ E E+ G K YK Sbjct: 3 LEALFNPKSIAVIGASSKPGKIGYAIMKNLIEYGYEGKIYPVNIKGGEMEISGRKFKVYK 62 Query: 57 SVKDIPGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEI 116 S+ ++P EVD+AIIVVP KFV + +CG+KGVK V II++GFGE GEEGKK E++LVE Sbjct: 63 SILEVPDEVDMAIIVVPAKFVPQVVEECGQKGVKVVPIISSGFGELGEEGKKVEQQLVET 122 Query: 117 AHRYGMRIIGPNCVGIMNTHADLNATF-ITVAKKGNVAFISQSGALGAGIVYKTIKEDIG 175 A +YGMRI+GPN G++ T A LN TF T G +A ISQSGALG ++ TI E IG Sbjct: 123 ARKYGMRILGPNIFGVVYTPAKLNGTFGPTDVLPGPLALISQSGALGIALMGWTILEKIG 182 Query: 176 FSKFISVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIAL 235 S +SVGN AD+D A+L+E+ D E +AI +Y+EG+++GR+F+EVAK V+KKKP+I + Sbjct: 183 LSAVVSVGNKADIDDADLLEFFKDDENTRAILIYMEGVKDGRRFMEVAKEVSKKKPIIVI 242 Query: 236 KAGKSESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQ-PLPRGK 294 KAG+SE GA+AA+SHTGSLAGS IY AAFKQSGVL A TI E ARA + P P+G Sbjct: 243 KAGRSERGAKAAASHTGSLAGSDTIYSAAFKQSGVLRALTIGEAFDWARALSNLPEPQGD 302 Query: 295 RVAIMTNAGGPGVLTADELDKRGLKLANLEEKTIEELRSF---LPPMAAVKNPVDMIASA 351 V I+TN GG GV+ D ++ GLKL + +E+L+ F +PP + KNPVD+ A Sbjct: 303 NVVIITNGGGIGVMATDAAEEEGLKLYD----DLEQLKIFANHMPPFGSYKNPVDLTGMA 358 Query: 352 RGEDYYRTAKLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPVLAMFM 411 + Y + L P + +I + A + P + AE IIR E KP++ + Sbjct: 359 DAKSYEGAIRDALNHPEMHSIIVLYC--QTAVLDPRDLAEIIIREYNESGRKKPLVVAIV 416 Query: 412 AGYVSEKAKELLEKNGIPTYERPEDVASAAYALVEQAK 449 G +++A + L +NGIP Y PE A AL +K Sbjct: 417 GGIEAKEAIDTLNENGIPAYPEPERAVKALSALYRWSK 454 >pir||A71028 hypothetical protein PH1517 - Pyrococcus horikoshii >gi|3257942|dbj|BAA30625.1| (AP000006) 460aa long hypothetical protein [Pyrococcus horikoshii] Length = 460 Score = 392 bits (997), Expect = e-108 Identities = 221/458 (48%), Positives = 299/458 (65%), Gaps = 16/458 (3%) Query: 2 LDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYK-GGNVYPVNVR--EEEVQG--VKAYK 56 L+ FNPK IAVIGAS+ P K+GY + KNL +Y G +YPVN++ E E+ G K YK Sbjct: 3 LEALFNPKSIAVIGASSKPGKIGYAIMKNLIEYGYEGKIYPVNIKGGEMEISGRKFKVYK 62 Query: 57 SVKDIPGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEI 116 S+ ++P EVD+A+IVVP K V + + +CG+KGVK II++GFGE GEEGKK E++LVE Sbjct: 63 SILEVPDEVDMAVIVVPAKSVPEVVEECGKKGVKVAPIISSGFGELGEEGKKVEQQLVET 122 Query: 117 AHRYGMRIIGPNCVGIMNTHADLNATF-ITVAKKGNVAFISQSGALGAGIVYKTIKEDIG 175 A +YGMRI+GPN G++ T A LNATF T G +A ISQSGALG ++ TI E IG Sbjct: 123 ARKYGMRILGPNIFGVVYTPAKLNATFGPTDVLPGPLALISQSGALGIALMGWTILEKIG 182 Query: 176 FSKFISVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIAL 235 S +SVGN AD+D A+L+E+ D E KAI +Y+EG+++GR+F+EVAK V+KKKP+I + Sbjct: 183 LSAVVSVGNKADIDDADLLEFFKDDENTKAILIYMEGVKDGRRFMEVAKEVSKKKPIIVI 242 Query: 236 KAGKSESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQ-PLPRGK 294 KAG+SE GA+AA+SHTGSLAGS IY AAFKQ+GVL A TI E ARA + P P+G+ Sbjct: 243 KAGRSERGAKAAASHTGSLAGSDTIYSAAFKQTGVLRALTIGEAFDWARALSNLPEPQGE 302 Query: 295 RVAIMTNAGGPGVLTADELDKRGLKLANLEEKTIEELRSF---LPPMAAVKNPVDMIASA 351 V I+TN GG GV+ D ++ GL L + +E+L+ F +PP + KNPVD+ A Sbjct: 303 NVVIITNGGGIGVMATDAAEEEGLHLYD----DLEQLKIFANHMPPFGSYKNPVDLTGMA 358 Query: 352 RGEDYYRTAKLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPVLAMFM 411 + Y + L P DM I + A + P E A+ IIR E KP++ + Sbjct: 359 DAKSYEGAIRDALAHP--DMHSIIVLYCQTAVLDPRELADVIIREYNESGRKKPLVVAIV 416 Query: 412 AGYVSEKAKELLEKNGIPTYERPEDVASAAYALVEQAK 449 G +++A ++L +NGIP Y PE A AL + +K Sbjct: 417 GGIEAKQAIDVLNENGIPAYPEPERAVKALSALYKWSK 454 >pir||E71189 hypothetical protein PH1789 - Pyrococcus horikoshii >gi|3258225|dbj|BAA30908.1| (AP000007) 472aa long hypothetical protein [Pyrococcus horikoshii] Length = 472 Score = 388 bits (985), Expect = e-107 Identities = 203/460 (44%), Positives = 287/460 (62%), Gaps = 18/460 (3%) Query: 5 FFNPKGIAVIGASNDPKKLGYEVFKNLKQYKG-----GNVYPVNVREEEVQGVKAYKSVK 59 FF PK +A+IGA+N K+G +F+N K+ K GN+YPVN + +E++G K Y V Sbjct: 13 FFEPKAVAIIGATNKKGKVGNVIFENFKKNKEKGIFKGNIYPVNPKLDEIEGYKVYHDVS 72 Query: 60 DIPGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHR 119 ++P + DLA+I +P V +T+ + GEKG+K V+IIT GFGE GEEGK+ E+E++EIA Sbjct: 73 ELPDDTDLAVIAIPAPAVPETMRKIGEKGIKSVIIITGGFGELGEEGKRMEQEILEIARA 132 Query: 120 YGMRIIGPNCVGIMNTHADLNATFITVAK-----KGNVAFISQSGALGAGIVYKTIKEDI 174 G+R+IGPNCVG+ ++ F+ K G +AFISQSGA A ++ I Sbjct: 133 NGIRVIGPNCVGVYVPDTGVDTVFLPDEKMDRPPSGPIAFISQSGAFAAAMLDWAAMAGI 192 Query: 175 GFSKFISVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIA 234 G K +S GN D+D A+LMEY A +E K + YIEG+++GRKF+E AKRVTK KP+IA Sbjct: 193 GIGKMVSYGNKIDVDDADLMEYFAHDDEIKVMTFYIEGVKDGRKFMETAKRVTKIKPIIA 252 Query: 235 LKAGKSESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQ-PLPRG 293 LK+G++E GA+AASSHTGSLAG IY+A FKQ+G++ A + M +A+AF + LP+G Sbjct: 253 LKSGRTEYGAKAASSHTGSLAGQDVIYDAVFKQTGIIRAEDFEHMFDLAKAFAKCKLPKG 312 Query: 294 KRVAIMTNAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARG 353 R+ I+T+ GG GV+ +D + K GLKLA L E+TI+ LR PP A V NP D++ Sbjct: 313 DRIGIITDGGGAGVMASDAVAKFGLKLAELSEETIKFLRERFPPHAVVGNPTDVVGDTDA 372 Query: 354 EDYYRTAKLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEV--NNGKPVLAMFM 411 E Y + +DPNVD ++ I + P E +I I + + KP++ + M Sbjct: 373 ERYRLALEAFTKDPNVDAILLIVLF-----QVPLLDEEEVINIITDYAKKSDKPIVVVSM 427 Query: 412 AGYVSEKAKELLEKNGIPTYERPEDVASAAYALVEQAKNV 451 GY ++K +LE+ GIP Y PE A LV AK + Sbjct: 428 GGYKTDKYARMLEERGIPVYPTPERGVRALAGLVRYAKYI 467 >pir||E75149 succinyl-coa synthetase alpha chain related protein PAB2112 - Pyrococcus abyssi (strain Orsay) >gi|5457786|emb|CAB49276.1| (AJ248284) SUCCINYL-COA SYNTHETASE ALPHA CHAIN related protein [Pyrococcus abyssi] Length = 472 Score = 383 bits (973), Expect = e-105 Identities = 200/460 (43%), Positives = 287/460 (61%), Gaps = 18/460 (3%) Query: 5 FFNPKGIAVIGASNDPKKLGYEVFKNLKQYKG-----GNVYPVNVREEEVQGVKAYKSVK 59 FF P+ +A+IGA+N K+G +F+N K+ K GN+YPVN + +E+ G K Y V Sbjct: 13 FFEPRAVAIIGATNKKGKVGNVIFENFKRNKEKGIFKGNIYPVNPKLDEIDGYKVYHDVS 72 Query: 60 DIPGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHR 119 ++P + DLA+I +P V +T+ + EKG+K V+IIT GFGE GEEGK+ E+E++EIA Sbjct: 73 ELPDDTDLAVIAIPAPAVPETMKKIAEKGIKAVIIITGGFGELGEEGKRMEQEILEIARA 132 Query: 120 YGMRIIGPNCVGIMNTHADLNATFITVAK-----KGNVAFISQSGALGAGIVYKTIKEDI 174 G+R+IGPNCVG+ ++ F+ K G +AFISQSGA A ++ I Sbjct: 133 NGIRVIGPNCVGVYAPDTGVDTVFLPEEKMDRPKSGPIAFISQSGAFAAAMLDWAAMAGI 192 Query: 175 GFSKFISVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIA 234 G K +S GN D+D A+LMEY A +E K + YIEG+++GRKF+E AKRVTK KP+IA Sbjct: 193 GIGKMVSYGNKIDVDDADLMEYFAQDDEIKVMTFYIEGVKDGRKFMETAKRVTKIKPIIA 252 Query: 235 LKAGKSESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQ-PLPRG 293 LK+G++E GA+AASSHTGSLAG IY+A FKQ+G++ A + M +A+AF + LP+G Sbjct: 253 LKSGRTEYGAKAASSHTGSLAGQDVIYDAVFKQTGIIRAEDFEHMFDLAKAFAKCKLPKG 312 Query: 294 KRVAIMTNAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARG 353 R+ I+T+ GG GV+ +D + K GLKLA L E+TI+ L+ PP A V NP D++ Sbjct: 313 DRIGIITDGGGAGVMASDAVAKFGLKLAELSEETIKFLKERFPPHAVVGNPTDVVGDTDA 372 Query: 354 EDYYRTAKLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEV--NNGKPVLAMFM 411 E Y + ++DPNVD ++ I + P + +I I + + KP++ + M Sbjct: 373 ERYRLALEAFIKDPNVDAILLIVLF-----QVPLLDEKEVIDIITDYAKKSDKPIVVVSM 427 Query: 412 AGYVSEKAKELLEKNGIPTYERPEDVASAAYALVEQAKNV 451 GY ++K ++LE+ GIP Y PE A LV AK V Sbjct: 428 GGYKTDKYAKMLEERGIPVYPTPERGVRALAGLVRYAKYV 467 >sp|Q58010|Y590_METJA HYPOTHETICAL PROTEIN MJ0590 >gi|2128020|pir||F64373 hypothetical protein homolog MJ0590 - Methanococcus jannaschii >gi|1591298|gb|AAB98580.1| (U67507) conserved hypothetical protein [Methanococcus jannaschii] Length = 704 Score = 383 bits (973), Expect = e-105 Identities = 212/445 (47%), Positives = 294/445 (65%), Gaps = 14/445 (3%) Query: 2 LDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYKGGNVYPVNVREEEVQGVKAYKSVKDI 61 L Y PK +A+IGAS K+GY + KNLK + G +YP+N + +E+ G+K YKSV D+ Sbjct: 8 LKYISYPKSVAIIGASKTEGKVGYAIMKNLKDFNG-KIYPINPKYDEIFGIKCYKSVLDV 66 Query: 62 PGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRYG 121 ++DLA+IVVP V L +CG+KGVKG VIITAGF E G + E ++ EIA RY Sbjct: 67 EDDIDLAVIVVPNIVVPKVLEECGKKGVKGAVIITAGFSEVGNY--ELENKIKEIAKRYN 124 Query: 122 MRIIGPNCVGIMNTHADLNATFITV-AKKGNVAFISQSGALGAGIVYKTIKEDIGFSKFI 180 +RIIGPNC+GIMNTH +LNATF V KG V+ ISQSGA+ I+ +IGFSK + Sbjct: 125 IRIIGPNCLGIMNTHINLNATFAKVFPPKGGVSIISQSGAVLNAILDIAPLLNIGFSKVV 184 Query: 181 SVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKAGKS 240 S+GN AD+ ++L+EY D E+ K + LYIEG+++ ++F++VAK+++KKKP+IALK+G++ Sbjct: 185 SIGNKADIQESDLLEYFLDDEDTKIVVLYIEGLKD-KRFLKVAKKLSKKKPIIALKSGRT 243 Query: 241 ESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAF-TQPLPRGKRVAIM 299 E G +AA SHTGSLAG IYEAAFK++G++ A T +E++ + F TQP + I+ Sbjct: 244 EVGKKAAKSHTGSLAGEDVIYEAAFKEAGIIRAYTFEELVDLIHLFSTQPTISSNEIGII 303 Query: 300 TNAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARGEDYYRT 359 TNAGG GVL AD +KL+N E+ TIE+L++ LPP A + NP+D+I A E Y + Sbjct: 304 TNAGGFGVLAADSCVDYNMKLSNFEKSTIEKLKNILPPTANISNPLDIIGDATPERYKKV 363 Query: 360 AKLLLQDPNVDMLIAICVVPTFAGMT-PTEHAEGII---RAIKEVNNGKPVLAMFMAGYV 415 ++L +D NV L+ V+ T MT P E A+ II + KE N KP++ F+ G Sbjct: 364 IEVLAEDSNVKGLL---VILTPQEMTKPLEVAKSIIEVKNSHKEFKN-KPLITSFVGGVS 419 Query: 416 SEKAKELLEKNGIPTYERPEDVASA 440 + AK L KNGIP Y PE+ A Sbjct: 420 VKGAKSYLRKNGIPAYITPENGVKA 444 >pir||A75021 succinyl-coa synthetase alpha chain related protein PAB1230 - Pyrococcus abyssi (strain Orsay) >gi|5459121|emb|CAB50607.1| (AJ248288) SUCCINYL-COA SYNTHETASE ALPHA SUBUNIT RELATED PROTEIN [Pyrococcus abyssi] Length = 466 Score = 382 bits (970), Expect = e-105 Identities = 214/468 (45%), Positives = 296/468 (62%), Gaps = 22/468 (4%) Query: 2 LDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYKGGNVYPVNVR--EEEVQG--VKAYKS 57 LD+ F P+ +AVIGAS+ P K+G + ++L G +Y VNV+ E EV G K Y+S Sbjct: 6 LDFLFYPRSVAVIGASHVPGKVGNAILRSLVNGFNGKIYAVNVKGGEIEVNGKKFKVYRS 65 Query: 58 VKDIPGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIA 117 VK+IP EVD+A+I VP KFV D + +CGEKGVKGVV+I+AGF E G +EE LV+ A Sbjct: 66 VKEIPDEVDVAVIAVPAKFVPDVIDECGEKGVKGVVVISAGFKEAGRADLEEE--LVKRA 123 Query: 118 HRYGMRIIGPNCVGIMNTHADLNATFITVAKK-----GNVAFISQSGALGAGIVYKTIKE 172 ++G+R++GPNC+G+ N + F ++ G +AF+SQSGA GA I+ + Sbjct: 124 RKWGIRVVGPNCLGVTNIENGFDCNFNPPERQARPKFGPIAFMSQSGAFGAAILDWAARH 183 Query: 173 DIGFSKFISVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPV 232 ++G SKFIS+GNMADLD ++ M YL D + K I YIEG+++GRKF AK TK KPV Sbjct: 184 EVGMSKFISLGNMADLDESDFMLYLKDDPKTKVITAYIEGVKDGRKFFNAAKETTKVKPV 243 Query: 233 IALKAGKSESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQPLP- 291 I LKAG++E+GA+AA+SHTGSLAGS+KIYEAAFKQSGVL+A ++ ++ + A+A P Sbjct: 244 IILKAGRTEAGAKAAASHTGSLAGSYKIYEAAFKQSGVLMAKSMRQLFNYAKALAMQNPA 303 Query: 292 RGKRVAIMTNAGGPGVLTADELDKRGLKLANLEEKTIEELRSF-----LPPMAAVKNPVD 346 +G RVAI+TN GG GV+ +D L + GLKLA E+T E+ R LP + +NPVD Sbjct: 304 KGDRVAIVTNGGGAGVMMSDGLLEHGLKLAEFTEETKEKFRKAIEEGKLPEHMSYRNPVD 363 Query: 347 MIASARGEDYYRTAKLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPV 406 +I A Y + +L+DPNVD+++ V+ F E ++ +KE GKP+ Sbjct: 364 VIGDAPSSRYEVAIRYVLEDPNVDIVV---VIALFQSPALDEGIVDVMGRVKEY--GKPI 418 Query: 407 LAMFMAGYVSEKAKELLEKNGIPTYERPEDVASAAYALVEQAKNVGVL 454 + + G E +EK GIP +E ED A YALV K + L Sbjct: 419 VFVAPGGEFPEAMARRIEKVGIPVFETVEDGVDAVYALVSYGKYLSEL 466 >pir||H71207 hypothetical protein PH1928 - Pyrococcus horikoshii >gi|3258372|dbj|BAA31055.1| (AP000007) 466aa long hypothetical protein [Pyrococcus horikoshii] Length = 466 Score = 375 bits (952), Expect = e-103 Identities = 209/469 (44%), Positives = 296/469 (62%), Gaps = 24/469 (5%) Query: 2 LDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYKGGNVYPVNVR--EEEVQG--VKAYKS 57 LD+ F P+ +AVIGAS+ P K+G + ++L G +Y VNV+ E EV G K YKS Sbjct: 6 LDFLFYPESVAVIGASHVPGKVGNGILRSLVNNFRGKIYAVNVKGGEIEVNGKKFKVYKS 65 Query: 58 VKDIPGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIA 117 +KD+P +VD+A+I VP KFV + + +CGEKGVKGVV+I+AGF E G +EE LV+ A Sbjct: 66 IKDVPDKVDVAVIAVPAKFVPEVIDECGEKGVKGVVVISAGFKEAGRADLEEE--LVKRA 123 Query: 118 HRYGMRIIGPNCVGIMNTHADLNATFITVAKK-----GNVAFISQSGALGAGIVYKTIKE 172 ++G+R++GPNC+G+ N + F ++ G +AF+SQSGA GA I+ + Sbjct: 124 KKWGIRVVGPNCLGVTNLENGFDCNFNPPERQARPKFGPIAFMSQSGAFGAAILDWAARH 183 Query: 173 DIGFSKFISVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPV 232 ++G SKFIS+GNMADLD ++ M YL + + K I YIEG+++G+KF VAK TK KPV Sbjct: 184 EVGMSKFISLGNMADLDESDFMLYLKNDPKTKVITAYIEGVKDGKKFFNVAKETTKVKPV 243 Query: 233 IALKAGKSESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQPLP- 291 I LKAG++E+GA+AA+SHTGSLAGS++IYEA F+Q+G+L A ++ ++ + A+A P Sbjct: 244 IVLKAGRTEAGAKAAASHTGSLAGSYRIYEAVFEQTGILAAKSMRQLFNYAKALAMQKPA 303 Query: 292 RGKRVAIMTNAGGPGVLTADELDKRGLKLANLEEKTIEELRSF-----LPPMAAVKNPVD 346 G RVAI+TN GG GV+ +D L +RGLKLA L E+T ++ R LP + NPVD Sbjct: 304 NGDRVAIVTNGGGAGVMMSDGLLERGLKLAELSEETKDKFRKAIEEGKLPEHMSYANPVD 363 Query: 347 MIASARGEDYYRTAKLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNN-GKP 405 +I A Y +L+DPNVD+L I + + A EGI+ + V GKP Sbjct: 364 VIGDAPSSRYELAINYVLEDPNVDILAVIALFQSPA------LDEGIVDVMDRVKKYGKP 417 Query: 406 VLAMFMAGYVSEKAKELLEKNGIPTYERPEDVASAAYALVEQAKNVGVL 454 ++ + G EK +EK G+P +E ED A YALV+ K + L Sbjct: 418 IVFIAPGGEFPEKIARRIEKVGVPVFETVEDGVDAVYALVKYGKYLSEL 466 >gi|11498810 conserved hypothetical protein [Archaeoglobus fulgidus] >gi|7448044|pir||B69401 conserved hypothetical protein AF1211 - Archaeoglobus fulgidus >gi|2649370|gb|AAB90033.1| (AE001020) conserved hypothetical protein [Archaeoglobus fulgidus] Length = 685 Score = 369 bits (937), Expect = e-101 Identities = 197/449 (43%), Positives = 290/449 (63%), Gaps = 13/449 (2%) Query: 2 LDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYKGGNVYPVNVREEEVQGVKAYKSVKDI 61 ++ F PK +AVIGAS K+G + KNL+ + G VY VN + E+ G Y SV I Sbjct: 1 MERLFYPKVVAVIGASPQEGKVGNTIMKNLRNFSG-TVYAVNPKYREILGFPCYPSVLKI 59 Query: 62 PGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRYG 121 P VDLAIIVVP K V + +CG K V+G V+I+AGF E G EG K E+ELVE+A RYG Sbjct: 60 PENVDLAIIVVPAKLVPKAVEECGRKDVEGAVVISAGFKEAGIEGAKLERELVEVAERYG 119 Query: 122 MRIIGPNCVGIMNTHADLNATFITVA-KKGNVAFISQSGALGAGIVYKTIKEDIGFSKFI 180 ++++GPNC+G++NT +NATF VA +KG +AF+SQSGA ++ + + +GFSK + Sbjct: 120 VKLVGPNCLGMINTEIAMNATFSRVAPEKGRIAFLSQSGAFILAVLEWSKRNGVGFSKVV 179 Query: 181 SVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKAGKS 240 S+GN A LD ++ +EYLA + I +Y+EG+ +GRKF+ VAK V ++KPV+ +KAGKS Sbjct: 180 SLGNKAMLDESDFLEYLAKDDSTDVILIYMEGVEDGRKFMRVAKSVARRKPVVVMKAGKS 239 Query: 241 ESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQPLPRGKRVAIMT 300 +SGA+AASSHTGSLAGS++ Y AAF+QSGV+ A++++E+ A + G +AI+T Sbjct: 240 QSGAKAASSHTGSLAGSYEAYRAAFRQSGVIEASSVEELFDFALLLLKYRKAG-NLAILT 298 Query: 301 NAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARGEDYYRTA 360 N+GGPGV+ AD D+ G+ LAN +TI +L+ FLP + NPVD++ A E + R+ Sbjct: 299 NSGGPGVMAADACDQFGVPLANFNFETIRKLKEFLPAESNFYNPVDILGDASAERFSRSL 358 Query: 361 KLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPVLAMFMAGYVSEKAK 420 ++L +D NVD+++ I +TPT + ++A + V GK + FM G ++++ Sbjct: 359 QILSEDENVDIVLTI--------LTPTAQMD-FLKAAESV-VGKNAVCCFMGGESVDESE 408 Query: 421 ELLEKNGIPTYERPEDVASAAYALVEQAK 449 +L +GIP + P A L +K Sbjct: 409 RILRSSGIPNFFDPVRAVRAISVLGRYSK 437 >pir||F75054 hypothetical protein PAB1431 - Pyrococcus abyssi (strain Orsay) >gi|5458844|emb|CAB50331.1| (AJ248287) hypothetical protein [Pyrococcus abyssi] Length = 442 Score = 365 bits (926), Expect = e-100 Identities = 202/454 (44%), Positives = 280/454 (61%), Gaps = 15/454 (3%) Query: 2 LDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYK-GGNVYPVNVREEEVQGV-KAYKSVK 59 +DYFF PK +A+ G+ + + E+ +N+ + G + PVN + V+ + ++ K Sbjct: 1 MDYFFYPKSVAIFGSFREGA-IAREILRNIVEGGFEGKIIPVNPKGGTVEVAGRRFEIRK 59 Query: 60 DIPGEVDLAIIVVPKKFVKDTLIQCGEKGV-KGVVIITAGFGETGEEGKKEEKELVEIAH 118 + EVD++I+V+P K V + + KG+ KG V+I+AGF E G +EE L++ A Sbjct: 60 RLEEEVDVSIVVIPAKLVPGLIREL--KGLTKGAVVISAGFSEVGNVDLEEE--LIKAAK 115 Query: 119 RYGMRIIGPNCVGIMNTHADLNATFITVAKKGNVAFISQSGALGAGIVYKTIKEDIGFSK 178 G+RIIGPNC GI H +F G +A ISQSGA G + +E++GFS Sbjct: 116 EAGIRIIGPNCAGIFGVHGKFFGSFEVRVNPGGLALISQSGAFGGAALAMGNEENVGFSA 175 Query: 179 FISVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKAG 238 F+S GN ADLD ++ + Y AD E K IALYIEG+++GRKF E K T KKPVI LKAG Sbjct: 176 FVSYGNAADLDESDFLRYFADDENTKVIALYIEGVKDGRKFFEALKYATSKKPVIILKAG 235 Query: 239 KSESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQPLPRGKRVAI 298 KSESGA+AA SHTGSLAGS++IY+A FKQ + ++E+ A+AF G RVA+ Sbjct: 236 KSESGAKAAQSHTGSLAGSYEIYKAVFKQGNAIEVEEMEELFDAAKAFEMYQSAGSRVAV 295 Query: 299 MTNAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARGEDYYR 358 +TN+GGPGVL D+L+K GL++A L E+T+ +LR FLPP + +NP+D+IA A E Y R Sbjct: 296 ITNSGGPGVLATDKLEKLGLEIARLSEETVAKLREFLPPQCSTRNPIDLIADADYERYRR 355 Query: 359 TAKLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPVLAMFMAGYVSEK 418 T +++ QD NVD L+ ICV P F +E I RAI E KP++ FMAG + +K Sbjct: 356 TIEVVCQDENVDSLLVICVPPIFI------PSEEIARAIIEAKCNKPIIVNFMAGELVKK 409 Query: 419 AKELLEKNGIPTYERPEDVASAAYALVEQAKNVG 452 ELL +GI + PE A A Y L + KN G Sbjct: 410 GVELLNAHGIKNFPTPERAAKALYWL-SKRKNQG 442 >pir||H71106 hypothetical protein PH0625 - Pyrococcus horikoshii >gi|3257031|dbj|BAA29714.1| (AP000003) 440aa long hypothetical protein [Pyrococcus horikoshii] Length = 440 Score = 354 bits (900), Expect = 8e-97 Identities = 198/447 (44%), Positives = 274/447 (61%), Gaps = 16/447 (3%) Query: 2 LDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYK-GGNVYPVNVR--EEEVQGVKAYKSV 58 +DYFF PK +A+ G+ + E+ +N+ + G + PVN + E EV G + + Sbjct: 1 MDYFFYPKSVAIFGSFRKGS-IAREILRNIVEGGFEGKIIPVNPKGGEVEVSG-RRFIIK 58 Query: 59 KDIPGEVDLAIIVVPKKFVKDTLIQCGEKGV-KGVVIITAGFGETGEEGKKEEKELVEIA 117 + + VD++IIV+P K V + + KG+ KG V+I+AGF E G + E+EL+ A Sbjct: 59 RKLDEFVDVSIIVIPAKLVPGLIREL--KGLTKGAVVISAGFSEVGNV--ELEEELIRAA 114 Query: 118 HRYGMRIIGPNCVGIMNTHADLNATFITVAKKGNVAFISQSGALGAGIVYKTIKEDIGFS 177 G+RIIGPNC GI H +F G +A ISQSGA G + +E++GFS Sbjct: 115 KESGIRIIGPNCAGIFGVHGKFFGSFEVRVNPGGLALISQSGAFGGAALAMGNEENVGFS 174 Query: 178 KFISVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKA 237 F+S GN ADLD ++ + Y AD E K IALYIEG+++GRKF E K T KKPVI LKA Sbjct: 175 AFVSYGNAADLDESDFLRYFADDENTKVIALYIEGVKDGRKFFEALKYATSKKPVIILKA 234 Query: 238 GKSESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQPLPRGKRVA 297 GKS+SGA+AA SHTGSLAGS++IY+AAFKQ+ + ++E+ A+AF G RVA Sbjct: 235 GKSKSGAKAAQSHTGSLAGSYEIYQAAFKQANAIEVEEMEELFDAAKAFEMYKEAGSRVA 294 Query: 298 IMTNAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARGEDYY 357 ++TN+GGPGVL D+L+K GL++A L E T+++LR FLPP + KNP+D+IA A E Y Sbjct: 295 VITNSGGPGVLATDKLEKLGLEIAQLSEDTVKKLREFLPPQCSTKNPIDLIADADYERYK 354 Query: 358 RTAKLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPVLAMFMAGYVSE 417 RT +++ QD NVD L+ ICV P F +E I RAI E KP++ FM+G + Sbjct: 355 RTIEIVCQDENVDSLLVICVPPIFI------PSEEIARAIIEAKCDKPIIVNFMSGELVA 408 Query: 418 KAKELLEKNGIPTYERPEDVASAAYAL 444 +LL + I + PE A A Y L Sbjct: 409 NGVKLLNDHDIKNFPTPERAAKALYWL 435 >gi|11499106 conserved hypothetical protein [Archaeoglobus fulgidus] >gi|7483131|pir||F69438 conserved hypothetical protein AF1511 - Archaeoglobus fulgidus >gi|2649053|gb|AAB89736.1| (AE000998) conserved hypothetical protein [Archaeoglobus fulgidus] Length = 881 Score = 353 bits (896), Expect = 2e-96 Identities = 196/457 (42%), Positives = 294/457 (63%), Gaps = 14/457 (3%) Query: 2 LDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYK-GGNVYPVNVREEEVQGVKAYKSVKD 60 L +FFNP+ +AVIGAS D +K+G F NL Y+ G YPVN + + GV+AY ++ + Sbjct: 191 LKHFFNPESVAVIGASRDVEKVGGRTFYNLLTYRFNGVAYPVNRAAKAIMGVRAYPTISE 250 Query: 61 IPGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRY 120 +P EV+LA++ VP K+ + +CG+KGVK ++++TAGF E G EG + +K+LVEI +Y Sbjct: 251 VPDEVELAVLSVPVKYALEVAEECGKKGVKALLVLTAGFAEVGGEGVERQKKLVEICRKY 310 Query: 121 GMRIIGPNCVGIMNTHAD--LNATFI-TVAKKGNVAFISQSGALGAGIVYKTIKEDIGFS 177 GMR+IGPNC+GI+NT + L ATF T +G++AF SQSGA+G ++ + +G S Sbjct: 311 GMRLIGPNCMGIINTAPETRLLATFAPTPPNEGSIAFASQSGAVGLALMDRVNNYGLGLS 370 Query: 178 KFISVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKA 237 F+S+GN AD+ +L+E+ + K I LY E I N RKF +AKR++KKKP++A+ + Sbjct: 371 YFVSLGNSADITSNDLIEFWEEDGRTKLIMLYQESIPNPRKFARLAKRISKKKPILAIAS 430 Query: 238 GKSESGARAASSHTGSLAGSWKI-YEAAFKQSGVLVANTIDEMLSMAR-AFTQPLPRGKR 295 G + +GA+A +SHTG++ S I +A FKQ+G++ A++IDE+ S++ QPLP+G R Sbjct: 431 GVTPAGAKAVASHTGAIVSSSGIAIDALFKQTGIIRASSIDELFSISEFLLHQPLPKGNR 490 Query: 296 VAIMTNAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARGED 355 V I+TN GG G +T+D + GL++A L E+T E LR+ LP +A+VKNPVDM ASA Sbjct: 491 VCIVTNGGGLGAITSDWCHQVGLEIAELSERTQESLRNLLPEIASVKNPVDMTASADVRM 550 Query: 356 YYRTAKLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNN-GKPVLAMFMAGY 414 Y +T K + +D NVD +I I V + E + +I A K N+ GKPV+ + Y Sbjct: 551 YGQTLKTVAEDENVDAIICI-FVAAVSEEKSEEVEKAVISAAKYANSVGKPVVYI----Y 605 Query: 415 VSEKAKE--LLEKNGIPTYERPEDVASAAYALVEQAK 449 +S +K+ + ++ +P Y P A +VE AK Sbjct: 606 ISSDSKDGVIGDEVKVPVYVFPNTAAKVLGKVVEYAK 642 >emb|CAC12278.1| (AL445066) probable acetyl-CoA synthetase [Thermoplasma acidophilum] Length = 698 Score = 339 bits (859), Expect = 5e-92 Identities = 185/448 (41%), Positives = 277/448 (61%), Gaps = 13/448 (2%) Query: 2 LDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQ--YKGGNVYPVNVREEEVQGVKAYKSVK 59 L F P+ +AVIGAS D K+GY++ +NLK+ Y+G VYPVN + + G Y S+ Sbjct: 8 LKSLFYPESVAVIGASADKTKIGYQIVRNLKEGGYQG-KVYPVNRKGGNILGYTVYPSIG 66 Query: 60 DIPGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHR 119 D+P +VDLAII VP + + +CG+KGV G++++ +GF E G K E +LVE+ + Sbjct: 67 DVPDKVDLAIISVPAEHTPEAAEECGKKGVFGIIVVASGFSEVGR--KDLEDQLVEVCRK 124 Query: 120 YGMRIIGPNCVGIMNTHADLNATFIT-VAKKGNVAFISQSGALGAGIVYKTIKEDIGFSK 178 Y MR++GPN VG+MN LNA+F + G + +SQSGAL G+ T G S Sbjct: 125 YNMRLLGPNVVGLMNNVLKLNASFAPYLPYPGTIGMVSQSGALIVGLDAMTWSNKTGTSF 184 Query: 179 FISVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKAG 238 IS+GNMADLDF++L+ +LA+ I+LY EG++ GR+FI+ A+ + KKP++ LK+G Sbjct: 185 LISIGNMADLDFSDLVSFLAEDNNVSCISLYTEGLKAGRRFIDTARSI--KKPIVMLKSG 242 Query: 239 KSESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFT-QPLPRGKRVA 297 S+ G+ AA+SHTGSLAGS ++Y+ A KQ+GV+ AN+I+E+ ++ + QP G + Sbjct: 243 ISKHGSVAAASHTGSLAGSHRVYDGALKQAGVVRANSIEELFDLSLTLSLQPPMGGDNLM 302 Query: 298 IMTNAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARGEDYY 357 ++TN GG GVL D+ + G+ L + ++R +P + KNP+DM A A E Y Sbjct: 303 VVTNGGGIGVLATDQAELSGIPLQTPSDDLQAKIRQVIPSFGSTKNPIDMSAMATPEIYA 362 Query: 358 RTAKLLLQDPNVDMLIAI-CVVPTFAGMTPTEHAEGIIRAIKEVNNGKPVLAMFMAGYVS 416 T K +++D +VD L+ + C V A + P++ A+GII + N PV+A F+ G S Sbjct: 363 DTIKTVMEDDSVDGLVVLYCEV---ANLDPSDAAKGIINGVLSSNRKIPVVAGFVGGEHS 419 Query: 417 EKAKELLEKNGIPTYERPEDVASAAYAL 444 + A L KNGIPT++ P+ A AL Sbjct: 420 KNASLYLIKNGIPTFDSPDKAVKAMAAL 447 >gb|AAF88064.1|AF286346_1 (AF286346) acetyl-CoA synthetase [Entamoeba histolytica] Length = 713 Score = 327 bits (829), Expect = 2e-88 Identities = 182/442 (41%), Positives = 268/442 (60%), Gaps = 17/442 (3%) Query: 6 FNPKGIAVIGASNDPKKLGYEVFKNLKQ--YKGGNVYPVNVREEEVQGVKAYKSVKDIPG 63 FNPK + VIGAS+ + +GY V N+ + YKG N+YPV R+ E+ G K Y + I Sbjct: 7 FNPKSVPVIGASDRKESVGYAVMNNMIKGGYKG-NLYPVG-RKPELFGKKCYAKIGKIEE 64 Query: 64 EVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRYGMR 123 +VDLA+I +P KFV I+CGE GVKG++IITAGF E GEEGKK E+ +Y MR Sbjct: 65 KVDLAVIAIPAKFVPGVCIECGEAGVKGLIIITAGFAEAGEEGKKMCIEIQATCQKYNMR 124 Query: 124 IIGPNCVGIMNTHADLNATFITVAKK-GNVAFISQSGALGAGIVYKTIKEDIGFSKFISV 182 +IGPNC+GI+N +NA+F +V + G VAFISQSGAL I+ + +GFS F+S+ Sbjct: 125 MIGPNCLGIINPRDGVNASFASVMPEAGGVAFISQSGALCTAILDWAANQHVGFSYFVSI 184 Query: 183 GNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKAGKSES 242 G+ D D+A+L E+ A + +I +YIE I++ +KF+ A+ KP+I LKAGKS Sbjct: 185 GSSIDTDYADLFEFFAKDPKVTSILMYIESIKDAKKFVLRAREFAADKPIILLKAGKSSE 244 Query: 243 GARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAF-TQPLPRGKRVAIMTN 301 GA AA SHTGSLAG+ +Y+A F + G + ++I ++ A TQ +P+ R+ I+TN Sbjct: 245 GAAAAMSHTGSLAGNDAVYDAVFDRCGCIRVDSICDLWDCAHVLATQNIPQNNRLCIITN 304 Query: 302 AGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARGEDYYRTAK 361 AGGPGV++ D L LA L E T+ EL +FL P + NPVD++ A Y +T Sbjct: 305 AGGPGVISTDRLVSVHGHLAKLSESTMNELNAFLSPFWSHSNPVDVLGDATAGVYQKTLD 364 Query: 362 LLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPVLAMFMAGYVSEKAK- 420 ++++DP +D ++ + +TP + + A V +G G+V++K++ Sbjct: 365 IVIKDPQIDGVVVV--------LTPQAMTDPVAVAKSLVEHGPYQNQSLPHGWVNQKSEA 416 Query: 421 --ELLEKNGIPTYERPEDVASA 440 ++LE+ IP +E PE +A Sbjct: 417 GVKILEEGKIPNFETPERAVTA 438 >gb|AAK42002.1| Conserved hypothetical protein [Sulfolobus solfataricus] Length = 660 Score = 323 bits (818), Expect = 3e-87 Identities = 177/440 (40%), Positives = 264/440 (59%), Gaps = 15/440 (3%) Query: 2 LDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYKGGNVYPVNVREEEVQGVKAYKSVKDI 61 L+Y F P+ IAV+GAS +K+G +F+NL G +YP+N + E+V+GVKAYKSVK+I Sbjct: 4 LNYLFKPRSIAVVGASRHKEKVGNVIFRNLLSTFQGKLYPINTKAEDVEGVKAYKSVKEI 63 Query: 62 PGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRYG 121 P ++DL +I VP++ V T+ + EKGVK ++ITAGF E GEE K E E++ IA + G Sbjct: 64 PDDIDLGVIAVPREVVPQTMEEFVEKGVKASIVITAGFREVGEE--KLENEVISIARKGG 121 Query: 122 MRIIGPNCVGIMNTHADLNATFI-TVAKKGNVAFISQSGALGAGIVYKTIKEDIGFSKFI 180 +R++GPN GI+ + NATF T K+GNV + QSG LG ++ K IG S + Sbjct: 122 IRVLGPNTFGIITP--EFNATFTYTDVKRGNVGLVVQSGGLGVYMLNWAQKYRIGISYMV 179 Query: 181 SVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKAGKS 240 S+GN AD+ E++ YL+ E +AI +Y+EG+ +G F+E T++KPV+ LK G S Sbjct: 180 SLGNQADVKEYEVINYLSKDAETRAIFVYLEGVSDGNAFLEELPEATRRKPVVFLKGGVS 239 Query: 241 ESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQPLPRGKRVAIMT 300 SGA AA +HTGSLAGS+++++AA G ++ + + +ML++A+ P + + ++T Sbjct: 240 SSGASAAKTHTGSLAGSFEVFKAAVNTIGGILVDNLHDMLNLAKILMYSEPISEELLVIT 299 Query: 301 NAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARGEDYYRTA 360 N+GG GVL +DE+DK GL+L + E +EL LPP + KNP+D+ A E Y+ Sbjct: 300 NSGGHGVLVSDEIDKNGLRLVEIPEWMKKELTKILPPTSLPKNPLDLTGDADRERYHNAL 359 Query: 361 KLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPVLAMFMAGYVSEKAK 420 K++ ++D C P + R I GK V+ + M G + A Sbjct: 360 KIV---SSLD-----CTKLVIVQSLPMVSCSDVARVISNF-KGKGVIGVTM-GLDEDMAL 409 Query: 421 ELLEKNGIPTYERPEDVASA 440 ++LE GIP Y PED A Sbjct: 410 KILETTGIPGYTFPEDAVKA 429 >gb|AAD44021.1|AF107206_1 (AF107206) acetyl-CoA synthetase [Giardia intestinalis] Length = 726 Score = 309 bits (784), Expect = 3e-83 Identities = 176/451 (39%), Positives = 266/451 (58%), Gaps = 6/451 (1%) Query: 2 LDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYK-GGNVYPVNVREEEVQGVKAYKSVKD 60 L + NP +AVIGAS + K+G V N+K+ G VYP+N E+ G K YKSV D Sbjct: 15 LSFLTNPASVAVIGASPNAGKVGNTVVTNIKESGYTGKVYPINPTATEILGYKTYKSVLD 74 Query: 61 IPGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRY 120 +P +D+ I+V+P K V +C +K VK +V+ITAGF E G EG + E++L +I Sbjct: 75 VPDSIDVVIVVIPSKAVLAAAKECAQKKVKSLVVITAGFKEIGGEGVQMEQDLTKICKDA 134 Query: 121 GMRIIGPNCVGIMNTHADLNATFITVA-KKGNVAFISQSGALGAGIVYKTIKEDIGFSKF 179 G+R++GPNC+GI+ + LN TF + KG++AF+SQSGA+ I+ + IGFS F Sbjct: 135 GIRLVGPNCLGIVTPN--LNCTFASAKPSKGSIAFLSQSGAMLTSILDWALTNGIGFSNF 192 Query: 180 ISVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKAGK 239 IS+GN AD+D +L+ +A+ I LY+E I +GRKF+E KKPVI LK+G Sbjct: 193 ISLGNKADVDEVDLIMEVAEDPNTDIILLYLESIVDGRKFLEQIPTCVHKKPVIILKSGT 252 Query: 240 SESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAF-TQPLPRGKRVAI 298 S +GA AASSHTG+LAG+ ++ AF+++GVL A T+ ++ + R F + LP+G I Sbjct: 253 SAAGAAAASSHTGALAGNDIAFDLAFEKAGVLRAATMSDLFDLGRLFVSHRLPKGDNFVI 312 Query: 299 MTNAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARGEDYYR 358 +TNAGGPG++T D + + +A L +KT E L LP A+VKNPVD++ A + Y Sbjct: 313 VTNAGGPGIVTTDAFETYHVGMAALSDKTKEALAKVLPGEASVKNPVDIVGDAPPKRYED 372 Query: 359 TAKLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPVLAMFMAGYVSEK 418 ++ ++P + A+ +V P E AE R + + + V++ FM G ++ Sbjct: 373 ALEICFKEPPETVAGAVILVTPQGQTKPCEVAELCTRMYAKYPD-RLVVSAFMGGLTMQE 431 Query: 419 AKELLEKNGIPTYERPEDVASAAYALVEQAK 449 ++L +P + PE A A+++ K Sbjct: 432 PSKILNNAKMPVFPFPEPAIHATGAVLKYRK 462 >gi|11498792 conserved hypothetical protein [Archaeoglobus fulgidus] >gi|7483097|pir||G69398 conserved hypothetical protein AF1192 - Archaeoglobus fulgidus >gi|2649402|gb|AAB90053.1| (AE001022) conserved hypothetical protein [Archaeoglobus fulgidus] Length = 664 Score = 301 bits (763), Expect = 1e-80 Identities = 175/457 (38%), Positives = 273/457 (59%), Gaps = 22/457 (4%) Query: 2 LDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYK-GGNVYPVNVREEEVQGVKAYKSVKD 60 + +FF K +AVIGAS + K G V NLK G VYPVN E+ G K Y SV+ Sbjct: 218 ISFFFKAKSVAVIGASRNLLKPGGRVLSNLKHLGFRGKVYPVNPNAGEILGYKCYPSVRA 277 Query: 61 IPGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRY 120 IP +VDLA+I VP K + + +C EKGVKG+++++AGF E E+GK+ E+++VEIA + Sbjct: 278 IPDKVDLAVIAVPSKNAIEVVKECAEKGVKGIIVLSAGFAEGWEQGKELERQIVEIARKS 337 Query: 121 GMRIIGPNCVGIMNTHADLNATFITVAK--KGNVAFISQSGALGAGIVYKTIKEDIGFSK 178 GMRI+GPN +GI++ + L + F + K +GN+ ++QSGA+ I+ +GFSK Sbjct: 338 GMRIVGPNTMGILDPESGLTSFFSVLRKIGQGNIGVLAQSGAVANFILLPL--WHVGFSK 395 Query: 179 FISVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKAG 238 +++GN AD+ E++ +L E+ + +A Y+EG NGRKF E+ K T KP++ LK+G Sbjct: 396 IVAIGNKADVGEVEVLNFLLKDEKTRVVAAYLEGFTNGRKFYELMKAST--KPIVVLKSG 453 Query: 239 KSESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFT-QPLPRGKRVA 297 ++E+G R+A SHT S++ S +I+EAA KQ+GV +E++ A+A QPLPRG RV Sbjct: 454 RTEAGKRSALSHTASISTSEEIFEAACKQAGVAKVYDFEELVDAAKALALQPLPRGTRVG 513 Query: 298 IMTNAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDM--IASARGED 355 ++ +G V++AD + + GL+LA EKT+E L P ++ NP+D+ IA G++ Sbjct: 514 VIQPSGAECVMSADAVVENGLELAKYSEKTLERLYELAPEWHSINNPLDLYPIAEKSGDE 573 Query: 356 YY-RTAKLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPVLAMFMAGY 414 + K+ +D N+D ++A +P+ + G+ + KPVL M Sbjct: 574 VFNEVLKVFNEDENIDAIVAGVFIPSIMKL-------GVDFSWTR-KFSKPVL-FTMKDD 624 Query: 415 VSE--KAKELLEKNGIPTYERPEDVASAAYALVEQAK 449 + E +A+ +E++G+P Y PE A +V AK Sbjct: 625 IEELRQARIEIERSGVPVYPTPERAVRALRHMVTVAK 661 >pir||T35770 hypothetical protein SC8A6.03c SC8A6.03c - Streptomyces coelicolor >gi|3288603|emb|CAA19775.1| (AL031013) hypothetical protein SC8A6.03c [Streptomyces coelicolor A3(2)] Length = 714 Score = 295 bits (747), Expect = 7e-79 Identities = 170/456 (37%), Positives = 252/456 (54%), Gaps = 16/456 (3%) Query: 8 PKGIAVIGASNDPKKLGYEVFKNLKQYK-GGNVYPVNVREEEVQGVKAYKSVKDIPGEVD 66 P +AVIGAS +P K+G V +NL G ++PVN + +++ G KAYKSV D+PGEVD Sbjct: 261 PASVAVIGASGEPGKIGNSVMRNLVDGGFAGEIHPVNPKADDILGRKAYKSVTDVPGEVD 320 Query: 67 LAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRYGMRIIG 126 +A+ +P +FV L + G K + V+I +GF ETGE+ ++E +V +A R+G+R++G Sbjct: 321 VAVFAIPARFVAAALEEVGRKRIPNAVLIPSGFAETGEQALQDE--IVAVAERHGVRLLG 378 Query: 127 PNCVGIMNTHADLNATFITVAK-KGNVAFISQSGALGAGIVYKTIKEDIGFSKFISVGNM 185 PN G +T DL ATF T KG VA SQSG +G I+ G S + +GN Sbjct: 379 PNIYGYYSTWQDLCATFCTPYDVKGGVALTSQSGGIGMAILGFARTTKTGVSAIVGLGNK 438 Query: 186 ADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKAGKSESGAR 245 +DLD +L+ + + + IA+++E +++GR F+E A+ +KPV+ LKAG++ +GA+ Sbjct: 439 SDLDEDDLLTWFGEDPHTECIAMHLEDLKDGRAFVEAARATVPRKPVVVLKAGRTAAGAK 498 Query: 246 AASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAF-TQPLPRGKRVAIMTNAGG 304 AA SHTG+LAG +Y+ +Q+GV+ A ++EML ARA P P G V I+T AGG Sbjct: 499 AAGSHTGALAGDDAVYDDILRQAGVIRAPGLNEMLEYARALPVLPAPEGDNVVIITGAGG 558 Query: 305 PGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARGEDYYRTAKLLL 364 GVL +D + GL L + R+F+PP A NPVD+ Y T +L L Sbjct: 559 SGVLLSDAVTDNGLSLMEIPPDLDRAFRAFIPPFGAAGNPVDITGGEPPSTYEATIRLGL 618 Query: 365 QDPNVDMLIA----ICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPVLAMFMAGYVSEKAK 420 +DP + L+ V P M E ++ +E KPV+A E+A Sbjct: 619 EDPRIHALVLGYWHTIVTPP---MVFAELTARVVAEFRERGVEKPVVASLAGDVEVEEAC 675 Query: 421 ELLEKNGIPTY----ERPEDVASAAYALVEQAKNVG 452 + L + G+ Y E+P V A Y A +G Sbjct: 676 QYLFERGVVAYPYTTEKPVAVLGAKYRWARAAGLLG 711 >gi|11499522 conserved hypothetical protein [Archaeoglobus fulgidus] >gi|7483184|pir||A69492 conserved hypothetical protein AF1938 - Archaeoglobus fulgidus >gi|2648606|gb|AAB89317.1| (AE000970) conserved hypothetical protein [Archaeoglobus fulgidus] Length = 673 Score = 279 bits (706), Expect = 5e-74 Identities = 168/456 (36%), Positives = 264/456 (57%), Gaps = 21/456 (4%) Query: 6 FNPKGIAVIGASNDPKKLGYEVFKNLKQYKG-GNVYPVNVREEEVQGVKAYKSVKDIPGE 64 F PK +AVIGAS K G+ + NLKQ G +YPVN +++ +K Y S+ DIP E Sbjct: 222 FYPKSVAVIGASRTVGKPGFNIVWNLKQNGFMGKIYPVNPNADKILELKCYPSILDIPDE 281 Query: 65 VDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRYGMRI 124 VD+AII VP K V + + +C +KG+KG VI+++GF E GE+G + E+ ++EIA ++G+RI Sbjct: 282 VDMAIIAVPAKIVPEVMAECAQKGIKGAVIVSSGFSEEGEKGAEYERRVLEIAKKHGIRI 341 Query: 125 IGPNCVGIMNTHADLNATFI--TVAKKGNVAFISQSGALGAGIVYKTIKED---IGFSKF 179 GPN G++NT +F V KKGN+ I+Q+G L GI+ + + IGFSK Sbjct: 342 FGPNTTGVLNTENGFITSFAIQPVIKKGNIGIIAQTG-LFLGIMMDIVTSNHPSIGFSKI 400 Query: 180 ISVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKAGK 239 + +GN D++ E++++L E+ K I +Y+EGI+NGR F +VA + +KP++ K+G+ Sbjct: 401 VGMGNKIDVEDYEVLDFLLKDEQTKVIGIYMEGIKNGRAFYDVAS--SAEKPIVVFKSGR 458 Query: 240 SESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFT-QPLPRGKRVAI 298 +E G +AA SHT S+ G +++A +Q+ ++ + DE+ + +AF+ QPLP+G RVAI Sbjct: 459 TEYGQKAAMSHTASICGDDDVFDAVCRQANLVRVYSFDELFDVTKAFSLQPLPKGDRVAI 518 Query: 299 MTNAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVD---MIASARGED 355 + G V +D GLKLA + T++++ P V NP+D M+ Sbjct: 519 IHYTGSGCVQGSDAAYFAGLKLAEFSKDTVDKISEVTPEWHNVNNPIDIWPMVEYYGAFK 578 Query: 356 YYRTA-KLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPV-LAMFMAG 413 Y+TA + +++D VD +IA CV +A E +++K+ GKP+ + A Sbjct: 579 AYQTAIEAVMEDEGVDSVIA-CV---WANRLINADFEPDYKSLKKY--GKPIYFCVEGAR 632 Query: 414 YVSEKAKELLEKNGIPTYERPEDVASAAYALVEQAK 449 V K LE NGIP Y + + + + AK Sbjct: 633 DVVFDHKNALELNGIPVYTNVINAVNVLGKVTKYAK 668 >gi|11498537 conserved hypothetical protein [Archaeoglobus fulgidus] >gi|7483066|pir||D69366 conserved hypothetical protein AF0932 - Archaeoglobus fulgidus >gi|2649664|gb|AAB90306.1| (AE001039) conserved hypothetical protein [Archaeoglobus fulgidus] Length = 666 Score = 279 bits (706), Expect = 5e-74 Identities = 161/451 (35%), Positives = 259/451 (56%), Gaps = 12/451 (2%) Query: 2 LDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYKGGNVYPVNVREEEVQGVKAYKSVKDI 61 + +FF + +AVIGAS +P K+G V ++L K +YP+N E+ G+KAY SVK + Sbjct: 219 ISFFFKARSVAVIGASTNPIKVGNSVVRSLMSNKNLRIYPINPNASEILGLKAYPSVKSL 278 Query: 62 PGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETG-EEGKKEEKELVEIAHRY 120 P D+AI+ VP +FV D + + E GVKGVVII++GF E EEGK E+ L EIA +Y Sbjct: 279 PEVPDIAIVTVPAEFVLDAVREAAEAGVKGVVIISSGFKEAEVEEGKVREERLREIARKY 338 Query: 121 GMRIIGPNCVGIMNTHADLNATFITV---AKKGNVAFISQSGALGAGIVYKTIKEDIGFS 177 G+RI+GPN GI++ +NA+F + KKG +A +SQSG + I++K D GFS Sbjct: 339 GIRIVGPNTFGIVSVVGGINASFTPMFSEVKKGRIALVSQSGGICHYIIHKF--RDSGFS 396 Query: 178 KFISVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKA 237 + +GN D+DF ++M +L + E +A+Y+EGI NGR E KR+ +K V+ +K+ Sbjct: 397 HILHLGNRCDVDFPDVMRFLREDENTDVVAVYVEGIDNGRGLFEELKRLCSEKKVVVMKS 456 Query: 238 GKSESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQPLPRGKRVA 297 G+S +A+ SHTGS+AG ++++ +A KQ+G +V T E++ A A + G VA Sbjct: 457 GRSSVADKASVSHTGSMAGDYRVFASAMKQAGAVVVETPTELIDTAIAMEKFEVSG-GVA 515 Query: 298 IMTNAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARG-EDY 356 ++T G G++ AD ++ G +LA E+T+ +L+S LPP+ +NPVD+ S + + Sbjct: 516 VLTIQAGLGIVAADIIESSGGRLARFGEETVRKLKSLLPPITLRENPVDLSFSGLNLKVF 575 Query: 357 YRTAKLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPVLAMFMAGYVS 416 + +D +V +++ + V + + P E I+ I + + +L Sbjct: 576 AEVIDTVCRDDDVGLVMFLYAVAPPSWVLPAEVISQIMGRITKPS----ILGYSSTPENY 631 Query: 417 EKAKELLEKNGIPTYERPEDVASAAYALVEQ 447 + KE L+ + ++ E A A L E+ Sbjct: 632 AEIKEALKGSKTLIFDSVERAAKVAAILSEK 662 >pir||C82443 conserved hypothetical protein VCA0574 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9657984|gb|AAF96476.1| (AE004388) conserved hypothetical protein [Vibrio cholerae] Length = 893 Score = 261 bits (660), Expect = 1e-68 Identities = 156/454 (34%), Positives = 251/454 (54%), Gaps = 7/454 (1%) Query: 2 LDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYK-GGNVYPVNVREEEVQGVKAYKSVKD 60 L+ PK +AVIGAS + G V KNL Q G + PV V GV AYK++ D Sbjct: 4 LNQLLRPKSVAVIGASVRSFRAGNIVMKNLLQGGFDGAIMPVTPYYPAVCGVLAYKTISD 63 Query: 61 IPGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRY 120 +P D+AI+ Q EKGVK V+++++ +G++ + + + IA Sbjct: 64 LPIVPDIAILCTHASRNVSLFKQLAEKGVKQVIVLSSDMYSLDAQGEEIQAQCMTIAKSV 123 Query: 121 GMRIIGPNCVGIMNTHADLNATFITV-AKKGNVAFISQSGALGAGIVYKTIKEDIGFSKF 179 MRI+GPN +G++ N +F V A KGN+AF+SQS A+ I+ + IGFS F Sbjct: 124 NMRILGPNSLGLILPWMQFNGSFSPVSALKGNIAFVSQSAAVCTTILDWANDKGIGFSAF 183 Query: 180 ISVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKAGK 239 IS+GN +D+DFA+L++ L+ + AI LY++ IR+ R+F+ A+ ++ + ++ LK G+ Sbjct: 184 ISLGNASDIDFADLLDTLSTDKHTDAILLYVDTIRDARRFMSAARAASRNRRILVLKGGR 243 Query: 240 SESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQPLP-RGKRVAI 298 +++G +AA HTG IY++A +++G+L N E+ + T +P RG+R+AI Sbjct: 244 TKAGRKAAQMHTGGDDTLDIIYDSAIRRTGMLRVNNTHELFAAVETLTHSVPLRGERLAI 303 Query: 299 MTNAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARGEDYYR 358 +TN GGP ++ D L +RG KLA LE++ E+L LP + NPVD++ A Y Sbjct: 304 ITNGGGPAIMAVDALLERGGKLAQLEDEIYEKLNQSLPQSWSHSNPVDIVGDADHLRYVS 363 Query: 359 TAKLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGK--PVLAMFMAGYVS 416 T +LL+ N+D ++ + A T A+ ++ A+++ K +L + + Sbjct: 364 TLNILLESENIDAILIMHSPSAIAHSEQT--AQALVEAVQKHPRAKRFNILTNWSGELSA 421 Query: 417 EKAKELLEKNGIPTYERPEDVASAAYALVEQAKN 450 + A+ L + GIPTY PE +A LVE +N Sbjct: 422 KPARTLFNQAGIPTYRTPESAVTAFMHLVEYRRN 455 >dbj|BAA10925.1| (D64044) hypothetycal 67KD protein fragment in UNG 3' region [Escherichia coli] Length = 612 Score = 234 bits (590), Expect = 2e-60 Identities = 151/454 (33%), Positives = 238/454 (52%), Gaps = 19/454 (4%) Query: 2 LDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYK-GGNVYPVNVREEEVQGVKAYKSVKD 60 L+ PK IAVIGAS P + GY + +NL G V PV + V GV A+ + Sbjct: 6 LEALLRPKSIAVIGASMKPNRAGYLMMRNLLAGGFNGPVLPVTPAWKAVLGVLAWPDIAS 65 Query: 61 IPGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRY 120 +P DLA++ L + GEKG K +I++A + ++L A R+ Sbjct: 66 LPFTPDLAVLCTNASRNLALLEELGEKGCKTCIILSAP--------ASQHEDLRACALRH 117 Query: 121 GMRIIGPNCVGIMNTHADLNATFITVA-KKGNVAFISQSGALGAGIVYKTIKEDIGFSKF 179 MR++GPN +G++ LNA+F V K+G +AFISQS A+ I+ + +GFS F Sbjct: 118 NMRLLGPNSLGLLAPWQGLNASFSPVPIKRGKLAFISQSAAVSNTILDWAQQRKMGFSYF 177 Query: 180 ISVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKAGK 239 I++G+ D+D EL++YLA + AI LY+E + + R+F+ A+ ++ KP++ +K+G+ Sbjct: 178 IALGDSLDIDVDELLDYLARDSKTSAILLYLEQLSDARRFVSAARSASRNKPILVIKSGR 237 Query: 240 SESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQPLP-RGKRVAI 298 S + R + + AG ++AA +++G+L E+ S + P RG R+ I Sbjct: 238 SPAAQRLLN----TTAGMDPAWDAAIQRAGLLRVQDTHELFSAVETLSHMRPLRGDRLMI 293 Query: 299 MTNAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARGEDYYR 358 ++N P L D L R KLA L E+T ++LR LP A+ NP+D+ A E Y + Sbjct: 294 ISNGAAPAALALDALWSRNGKLATLSEETCQKLRDALPEHVAISNPLDLRDDASSEHYIK 353 Query: 359 TAKLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPV--LAMFMAGYVS 416 T +LL + D L+ I A TE A+ +I A+K K V L + + S Sbjct: 354 TLDILLHSQDFDALMVI--HSPSAAAPATESAQVLIEAVKHHPRSKYVSLLTNWCGEHSS 411 Query: 417 EKAKELLEKNGIPTYERPEDVASAAYALVEQAKN 450 ++A+ L + G+PTY PE +A +VE +N Sbjct: 412 QEARRLFSEAGLPTYRTPEGTITAFMHMVEYRRN 445 >sp|P76594|YFIQ_ECOLI HYPOTHETICAL 98.0 KD PROTEIN IN UNG-PSSA INTERGENIC REGION >gi|7466397|pir||G65036 hypothetical protein b2584 - Escherichia coli (strain K-12) >gi|1788938|gb|AAC75637.1| (AE000344) orf, hypothetical protein [Escherichia coli K12] Length = 886 Score = 234 bits (590), Expect = 2e-60 Identities = 151/454 (33%), Positives = 238/454 (52%), Gaps = 19/454 (4%) Query: 2 LDYFFNPKGIAVIGASNDPKKLGYEVFKNLKQYK-GGNVYPVNVREEEVQGVKAYKSVKD 60 L+ PK IAVIGAS P + GY + +NL G V PV + V GV A+ + Sbjct: 6 LEALLRPKSIAVIGASMKPNRAGYLMMRNLLAGGFNGPVLPVTPAWKAVLGVLAWPDIAS 65 Query: 61 IPGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRY 120 +P DLA++ L + GEKG K +I++A + ++L A R+ Sbjct: 66 LPFTPDLAVLCTNASRNLALLEELGEKGCKTCIILSAP--------ASQHEDLRACALRH 117 Query: 121 GMRIIGPNCVGIMNTHADLNATFITVA-KKGNVAFISQSGALGAGIVYKTIKEDIGFSKF 179 MR++GPN +G++ LNA+F V K+G +AFISQS A+ I+ + +GFS F Sbjct: 118 NMRLLGPNSLGLLAPWQGLNASFSPVPIKRGKLAFISQSAAVSNTILDWAQQRKMGFSYF 177 Query: 180 ISVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKAGK 239 I++G+ D+D EL++YLA + AI LY+E + + R+F+ A+ ++ KP++ +K+G+ Sbjct: 178 IALGDSLDIDVDELLDYLARDSKTSAILLYLEQLSDARRFVSAARSASRNKPILVIKSGR 237 Query: 240 SESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQPLP-RGKRVAI 298 S + R + + AG ++AA +++G+L E+ S + P RG R+ I Sbjct: 238 SPAAQRLLN----TTAGMDPAWDAAIQRAGLLRVQDTHELFSAVETLSHMRPLRGDRLMI 293 Query: 299 MTNAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASARGEDYYR 358 ++N P L D L R KLA L E+T ++LR LP A+ NP+D+ A E Y + Sbjct: 294 ISNGAAPAALALDALWSRNGKLATLSEETCQKLRDALPEHVAISNPLDLRDDASSEHYIK 353 Query: 359 TAKLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPV--LAMFMAGYVS 416 T +LL + D L+ I A TE A+ +I A+K K V L + + S Sbjct: 354 TLDILLHSQDFDALMVI--HSPSAAAPATESAQVLIEAVKHHPRSKYVSLLTNWCGEHSS 411 Query: 417 EKAKELLEKNGIPTYERPEDVASAAYALVEQAKN 450 ++A+ L + G+PTY PE +A +VE +N Sbjct: 412 QEARRLFSEAGLPTYRTPEGTITAFMHMVEYRRN 445 >emb|CAA10043.1| (AJ012480) pimeloyl-CoA synthetase [Pseudomonas mendocina] Length = 711 Score = 199 bits (501), Expect = 5e-50 Identities = 120/352 (34%), Positives = 189/352 (53%), Gaps = 9/352 (2%) Query: 8 PKGIAVIGASNDPKKLGYE-VFKNLKQYKGGNVYPVNVREEEVQGVKAYKSVKDIPGEVD 66 P+ +AV+GAS+DP ++G + L+ G + PVN E+QG+ AY SV +P D Sbjct: 20 PRSVAVVGASSDPHRIGGRPIAYMLRNGFTGRILPVNPNRTEIQGLPAYASVDALPEAPD 79 Query: 67 LAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRYGMRIIG 126 +AII VP V +T+ G KG + ++ ++GF E GEEG + +VE A MR++G Sbjct: 80 VAIIAVPAPQVLETVQVLGRKGARSAIVFSSGFSEVGEEGVAMQDAIVEAARAANMRLLG 139 Query: 127 PNCVGIMNTHADLNATFITVAKK-----GNVAFISQSGALGAGIVYKTIKEDIGFSKFIS 181 PN +G+ N + A F T ++ G V +QSGA GA ++ + + +G ++ Sbjct: 140 PNALGVFNANLGYYAFFSTSLERGIPLAGRVGIATQSGAYGAHLLGLSRQRGLGTPICVA 199 Query: 182 VGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKK-KPVIALKAGKS 240 GN AD+ + + +L ++ E + Y E IRN F+ + + KPVI K G+S Sbjct: 200 TGNEADVTLGDAIGWLVESPEVDVVMAYAESIRNVDSFLAALEAAHRAGKPVILHKVGRS 259 Query: 241 ESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQP-LPRGKRVAIM 299 E G RAA SHT SLAG K+ +A V+ A T +E++ +A TQ +P + ++ Sbjct: 260 ELGGRAAMSHTASLAGDDKVLDAVLADYAVVRARTTEELVDIAYLATQRIIPVNNSLGMI 319 Query: 300 TNAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASA 351 T +GG G++ +D + GL + + E+ L+ L A+ NPVD A A Sbjct: 320 TVSGGAGIIVSDAAEDVGLPMPPMPEEAQARLKQRL-HYASPLNPVDCTAQA 370 >pir||B83518 pimeloyl-CoA synthetase PA1017 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9946928|gb|AAG04406.1|AE004534_4 (AE004534) pimeloyl-CoA synthetase [Pseudomonas aeruginosa] Length = 715 Score = 197 bits (496), Expect = 2e-49 Identities = 117/352 (33%), Positives = 191/352 (54%), Gaps = 9/352 (2%) Query: 8 PKGIAVIGASNDPKKLGYE-VFKNLKQYKGGNVYPVNVREEEVQGVKAYKSVKDIPGEVD 66 P+ +AVIGAS+DP ++G + L+ G + PVN E+QG+ A+ SV ++P D Sbjct: 24 PRSVAVIGASSDPTRIGGRPIAYMLRHGYAGQILPVNPNRAEIQGLPAFASVAELPQAPD 83 Query: 67 LAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRYGMRIIG 126 +AI+ VP V +T+ G +G + ++ ++GF E GE G + +V A +GMR++G Sbjct: 84 VAIVAVPAPQVLETVRALGRQGARSAIVFSSGFSEVGEAGAAMQDAVVAAAREHGMRLLG 143 Query: 127 PNCVGIMNTHADLNATFIT-----VAKKGNVAFISQSGALGAGIVYKTIKEDIGFSKFIS 181 PN +G N++ A F T V G V +QSGA GA ++ + +G ++ Sbjct: 144 PNALGAFNSNLGYYAFFSTSLERGVPLPGRVGIATQSGAYGAHLLGMARQRRLGTPICVA 203 Query: 182 VGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKK-KPVIALKAGKS 240 GN AD+ + + +L ++ E + Y E IRN F+ + + KPVI K G+S Sbjct: 204 TGNEADVTLGDSIGWLVESPEIDVVMAYAESIRNVDSFLAALEAAHRAGKPVILHKVGRS 263 Query: 241 ESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQPL-PRGKRVAIM 299 G+RAA SHT SLAG K+ +A V+ A T +E++ +A T+ + P G + ++ Sbjct: 264 ALGSRAALSHTASLAGDDKVLDAVLGDYAVIRARTTEELMDIAYLATRRIYPVGNSLGMI 323 Query: 300 TNAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASA 351 T +GG G++ +D ++ GL + + + E L++ L A+ NPVD A A Sbjct: 324 TVSGGAGIIVSDVAEEVGLPMPPMPDMAQERLKARL-SFASPINPVDCTAQA 374 >pir||T35878 hypothetical protein SC9B10.09 - Streptomyces coelicolor >gi|2661695|emb|CAA15799.1| (AL009204) hypothetical protein SC9B10.09 [Streptomyces coelicolor A3(2)] Length = 1039 Score = 193 bits (486), Expect = 3e-48 Identities = 126/417 (30%), Positives = 202/417 (48%), Gaps = 37/417 (8%) Query: 8 PKGIAVIGASNDPKKLGYEVFKNLKQYK-GGNVYPVNVR----EEEVQGVKAYKSVKDIP 62 P +AV+GA P +G + N++ G +Y VN +E+ GV A +SV DI Sbjct: 212 PGSVAVVGAGRTPGGVGRSILGNIRDAGYTGRLYAVNRAFPEDMKELDGVPACRSVGDID 271 Query: 63 GEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRYGM 122 G VDLA++ VP + V D + CGE GV+G+V+I+AG+ ++G EG++ ++ LV A YGM Sbjct: 272 GPVDLAVVTVPAEHVPDVVTACGEHGVQGLVVISAGYADSGPEGRERQRALVRHARTYGM 331 Query: 123 RIIGPNCVGIMNTHAD--LNATFI-TVAKKGNVAFISQSGALGAGIVYKTIKED------ 173 RIIGPN GI+NT D LNA+ + + G + +QSGA+G ++ + + Sbjct: 332 RIIGPNAFGIINTSPDVRLNASLAPEMPRAGRIGLFAQSGAIGIALLSRLHRRGGGVTGV 391 Query: 174 IGFSKFISVGNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVI 233 G S F+S GN AD+ ++++Y D + +Y+E I N RKF +A+R KP++ Sbjct: 392 TGVSTFVSSGNRADVSGNDVLQYWYDDPQTDVALMYLESIGNPRKFTRLARRTAAAKPLV 451 Query: 234 ALKAGKSESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFT-QPLPR 292 ++ G G + A +Q+GV+ +TI +++ QPLP Sbjct: 452 VVQ-GARHGGVAPQGHAVRATRLPHATVSALLRQAGVIRVDTITDLVDAGLLLARQPLPA 510 Query: 293 GKRVAIMTNAGGPGVLTADELDKRGLKLANLEEKTIEELRSFLPPMAAVKNPVDMIASAR 352 G RVAI+ N+ G+LT D GL+ + P+D+ +A Sbjct: 511 GPRVAILGNSESLGLLTYDACLSEGLR---------------------PQPPLDLTTAAS 549 Query: 353 GEDYYRTAKLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGIIRAIKEVNNGKPVLAM 409 +D++ L D D ++ + G +R+ KPVL + Sbjct: 550 ADDFHAALARALADDTCDAVVVTAIPTLGEGAAGDAALAEALRSAAAAVPTKPVLVV 606 >gb|AAG19369.1| (AE005031) acetyl-CoA synthetase; Acs3 [Halobacterium sp. NRC-1] Length = 542 Score = 189 bits (475), Expect = 6e-47 Identities = 109/294 (37%), Positives = 166/294 (56%), Gaps = 5/294 (1%) Query: 155 ISQSGALGAGIVYKTIKEDIGFSKFISVGNMADLDFAELMEYLADTEEDKAIALYIEGIR 214 +SQSGA ++ + IGF S+GN A L + M+ AD + I Y+EG+ Sbjct: 1 MSQSGAFITAVLDWANDQGIGFKDIASLGNKAVLSETDFMQAWADDPDTNVILGYLEGVD 60 Query: 215 NGRKFIEVAKRVTKKKPVIALKAGKSESGARAASSHTGSLAGSWKIYEAAFKQSGVLVAN 274 +GR+FI+ A+ VT+ P + +K+G++E+GA+AASSHTG++AGS YEA FKQ+GV+ A Sbjct: 61 DGREFIDDAREVTQDTPAVVVKSGRTEAGAQAASSHTGTIAGSEAAYEAGFKQAGVVRAE 120 Query: 275 TIDEMLSMARAFT-QPLPRGKRVAIMTNAGGPGVLTADELDKRGLKLANLEEKTIEELRS 333 + E+ ARA P+P + VA++TNAGGPGV+ D + L +A+ E+ TI+ L+ Sbjct: 121 NVQELFDFARALDGLPMPDSEDVAVITNAGGPGVMATDAVGDSRLSMASFEDDTIDALQG 180 Query: 334 FLPPMAAVKNPVDMIASARGEDYYRTAKLLLQDPNVDMLIAICVVPTFAGMTPTEHAEGI 393 +P A V NPVD+I A + + +L D +V + + T G+ Sbjct: 181 SMPDEANVYNPVDVIGDAEIDRFRTAIDTVLADEHVGCALVLSAPTAVIDYT---ELSGV 237 Query: 394 IRAIKEVNNGKPVLAMFMAGYVSEKAKELLEKNGIPTYERPEDVASAAYALVEQ 447 I A++E +N KPV+ M G +E+A ++L GIP Y P + AL Q Sbjct: 238 ITALQEKHN-KPVVTCLMGGERTEQATDVLGDAGIPNYFDPARAIGSLDALAVQ 290 >pir||H83024 hypothetical protein PA4978 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9951261|gb|AAG08363.1|AE004910_10 (AE004910) hypothetical protein [Pseudomonas aeruginosa] Length = 696 Score = 159 bits (398), Expect = 6e-38 Identities = 108/326 (33%), Positives = 164/326 (50%), Gaps = 15/326 (4%) Query: 37 GNVYPVNVREEEVQGVKAYKSVKDIPGEVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIIT 96 G ++ VN + E++GV SV D+P D A + ++ D + KG G + Sbjct: 37 GQLWLVNPQHAELEGVPCVASVADLPCGPDAAFVATNRELTLDAVAALAAKGAGGAICYA 96 Query: 97 AGFGETGEEGKKEEKELVEIAHRYGMRIIGPNCVGIMN-THADLNATFITVAKKG----- 150 +GF ETGE+G ++ L+ A M ++GPNC G+++ H A VA G Sbjct: 97 SGFAETGEQGLAVQRRLLAAAGE--MALLGPNCYGLLDYLH---GAALWPVAHGGRQVER 151 Query: 151 NVAFISQSGALGAGIVYKTIKEDIGFSKFISVGNMADLDFAELMEYLADTEEDKAIALYI 210 VA ++QSG + + + SVGN A L AELM+ L D AI L++ Sbjct: 152 GVAVLTQSGNFAYNLSMSDRSLPVAY--MASVGNQAQLGIAELMDVLLDEPRVTAIGLHL 209 Query: 211 EGIRNGRKFIEVA-KRVTKKKPVIALKAGKSESGARAASSHTGSLAGSWKIYEAAFKQSG 269 EG++N F A K + K PVIALK G S+ GA A SHT SLAGS +Y++ F++ G Sbjct: 210 EGLKNVPGFARAAYKALQKGVPVIALKTGVSKIGAALALSHTSSLAGSDALYDSLFERLG 269 Query: 270 VL-VANTIDEMLSMARAFTQPLPRGKRVAIMTNAGGPGVLTADELDKRGLKLANLEEKTI 328 V+ V+ + + ++ A LP G + + +GG L AD ++ GL L + + Sbjct: 270 VIRVSGPVSFVETLKAAACGHLPGGPSLVALACSGGDAGLIADYAERNGLGLPSFDAGQR 329 Query: 329 EELRSFLPPMAAVKNPVDMIASARGE 354 +EL LP A + NP+D + G+ Sbjct: 330 DELAGVLPDYANIANPLDFTTAIWGD 355 >pir||A72707 probable succinyl-CoA synthetase alpha chain APE1072 - Aeropyrum pernix (strain K1) >gi|5104742|dbj|BAA80057.1| (AP000060) 297aa long hypothetical succinyl-CoA synthetase alpha chain [Aeropyrum pernix] Length = 297 Score = 88.5 bits (216), Expect = 1e-16 Identities = 78/272 (28%), Positives = 126/272 (45%), Gaps = 27/272 (9%) Query: 24 GYEVFKNLKQYKGGNVYPVNVREEEVQGVKAYKSVKDIPGE---VDLAIIVVPKKFVKDT 80 G +V + KGG+ EV GV Y SVK+ E ++ +I+ VP F D Sbjct: 37 GTKVVAGVTPGKGGS---------EVHGVPVYDSVKEALAEHPEINTSIVFVPAPFAPDA 87 Query: 81 LIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRYGMRIIGPNCVGIMNT-HADL 139 + + + G++ VV+IT G + V A + G IIGPNC G + A + Sbjct: 88 VYEAVDAGIRLVVVITEGIPV------HDTMRFVNYARQKGATIIGPNCPGAITPGQAKV 141 Query: 140 NATFITVAKKGNVAFISQSGALGAGIVYKTIKEDIGFSKFISVGN--MADLDFAELMEYL 197 + K+G VA +S+SG L I Y ++ IG S I +G + L F E ++ Sbjct: 142 GIMPGHIFKEGGVAVVSRSGTLTYEISYMLTRQGIGQSTVIGIGGDPIVGLSFTEALKLF 201 Query: 198 ADTEEDKAIALYIE-GIRNGRKFIEVAKRVTKKKPVIALKAGKSESGARAASSHTGSL-- 254 + + +A+ L E G + E+ K+ KPVIA AG++ + H G++ Sbjct: 202 QEDPQTEALVLIGEIGGDMEERAAEMIKKGEFTKPVIAYIAGRT-APPEKRMGHAGAIIM 260 Query: 255 --AGSWKIYEAAFKQSGVLVANTIDEMLSMAR 284 G+++ A +++GV VA T E+ + R Sbjct: 261 MGTGTYEGKVKALREAGVEVAETPFEVPELVR 292 >gi|11499767 succinyl-CoA synthetase, alpha subunit (sucD-2) [Archaeoglobus fulgidus] >gi|6647837|sp|O28098|SUD2_ARCFU SUCCINYL-COA SYNTHETASE ALPHA CHAIN 2 (SCS-ALPHA 2) >gi|7437885|pir||A69523 succinate--CoA ligase (ADP-forming) (EC 6.2.1.5) alpha-2 chain - Archaeoglobus fulgidus >gi|2648340|gb|AAB89067.1| (AE000954) succinyl-CoA synthetase, alpha subunit (sucD-2) [Archaeoglobus fulgidus] Length = 287 Score = 85.0 bits (207), Expect = 2e-15 Identities = 72/247 (29%), Positives = 114/247 (46%), Gaps = 23/247 (9%) Query: 48 EVQGVKAYKSVKDIPGEVDL--AIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEE 105 EV GV Y SVK+ E D ++I VP F D +++ + G+K +V IT G Sbjct: 47 EVLGVPVYDSVKEAVREADANASVIFVPAPFAADAVMEAADAGIKVIVCITEGIPV---- 102 Query: 106 GKKEEKELVEIAHRYGMRIIGPNCVGIMN---THADLNATFITVAKKGNVAFISQSGALG 162 +E ++ G +IGPNC GI++ TH L + + K GNV +S+SG L Sbjct: 103 --HDELKMYWRVKEAGATLIGPNCPGIISPGKTH--LGIMPVQIFKPGNVGIVSRSGTLT 158 Query: 163 AGIVYKTIKEDIGFSKFISVG--NMADLDFAELMEYLADTEEDKAIALYIE-GIRNGRKF 219 I Y K +G S + +G + DF E++ D +E KA+ L E G R+ Sbjct: 159 YQIAYNLTKLGLGQSTVVGIGGDRIIGTDFVEVLRLFEDDKETKAVVLVGEIGGRDEEVA 218 Query: 220 IEVAKRVTKKKPVIALKAGKSESGARAASSHTGSL----AGSWKIYEAAFKQSGVLVANT 275 E + ++ KPV+ AG + + H G++ G+ + A + +G V T Sbjct: 219 AEFIREMS--KPVVGYVAGLTAPPGK-RMGHAGAIIEGGVGTAESKIKALEAAGARVGKT 275 Query: 276 IDEMLSM 282 E+ + Sbjct: 276 PMEVAEL 282 >sp|Q58643|SUCD_METJA SUCCINYL-COA SYNTHETASE ALPHA CHAIN (SCS-ALPHA) >gi|2118349|pir||E64455 succinate--CoA ligase (ADP-forming) (EC 6.2.1.5) alpha chain - Methanococcus jannaschii >gi|1591879|gb|AAB99250.1| (U67565) succinyl-CoA synthetase, alpha subunit (sucD) [Methanococcus jannaschii] Length = 294 Score = 82.3 bits (200), Expect = 1e-14 Identities = 69/243 (28%), Positives = 115/243 (46%), Gaps = 19/243 (7%) Query: 47 EEVQGVKAYKSVKDIPGEVDL--AIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGE 104 + V GV + +VK+ E D ++I VP F KD + + + G++ +V+IT Sbjct: 51 QNVHGVPVFDTVKEAVKETDANASVIFVPAPFAKDAVFEAIDAGIELIVVITEHIPV--- 107 Query: 105 EGKKEEKELVEIAHRYGMRIIGPNCVGIMNTHAD-LNATFITVAKKGNVAFISQSGALGA 163 + E V A G++IIGPN GI + L + V K+G+V +S+SG L Sbjct: 108 ---HDTMEFVNYAEDVGVKIIGPNTPGIASPKVGKLGIIPMEVLKEGSVGMVSRSGTLTY 164 Query: 164 GIVYKTIKEDIGFSKFISVGN--MADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIE 221 I ++ K G S + +G + L + E+++ +E +AI + G G E Sbjct: 165 EIAHQIKKAGFGVSTCVGIGGDPIVGLRYKEVLDLFEKDDETEAIVMI--GEIGGGAEEE 222 Query: 222 VAKRVTK-KKPVIALKAGKSESGARAASSHTGSLA----GSWKIYEAAFKQSGVLVANTI 276 AK + K KKPVI AG+S + H G++ G+ + A +++G VA I Sbjct: 223 AAKFIEKMKKPVIGYIAGQSAPEGK-RMGHAGAIVEKGKGTAESKMKALEEAGAYVAKNI 281 Query: 277 DEM 279 ++ Sbjct: 282 SDI 284 >gb|AAK42618.1| Succinyl-CoA synthetase, alpha subunit (sucD) [Sulfolobus solfataricus] Length = 260 Score = 81.9 bits (199), Expect = 1e-14 Identities = 73/266 (27%), Positives = 117/266 (43%), Gaps = 30/266 (11%) Query: 22 KLGYEVFKNLKQYKGGNVYPVNVREEEVQGVKAYKSVKDI--PGEVDLAIIVVPKKFVKD 79 K G ++ + KGG +V V Y +VKD E D +II VP ++ D Sbjct: 3 KYGTKIVAGVTPGKGGT---------QVNSVPVYDTVKDAMKEHEADASIIFVPARYAVD 53 Query: 80 TLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRYGMRIIGPNCVGIMNTHADL 139 + + + G+K +V IT + ++ A G RIIGPNC GI+ L Sbjct: 54 AIYEAVDAGIKLIVTITEHIPVL------DMARAIKYARARGARIIGPNCPGIIAPEESL 107 Query: 140 NATFITVA-KKGNVAFISQSGALGAGIVYKTIKEDIGFSKFISVG-----NMADLDFAEL 193 A KKG + +S+SG L + +G S I +G + L+ A++ Sbjct: 108 VGILPARAFKKGKIGIVSRSGTLTYEVSELLKNSGMGQSTVIGIGGDPIIGTSTLEVAKM 167 Query: 194 MEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKAGKSESGARAASSHTGS 253 + D E +K + + G + E KR KKP+IA AG + + H G+ Sbjct: 168 FD--QDPETEKIVVIGEIGGTMEERLAEAYKRGEIKKPIIAYIAGMT-APREKRMGHAGA 224 Query: 254 LA----GSWKIYEAAFKQSGVLVANT 275 + G+++ AFK++G+ +ANT Sbjct: 225 VVYMGMGTFESKIRAFKEAGIPIANT 250 >gb|AAA27504.2| (M35832) succinyl-CoA synthetase alpha-subunit [Thermus aquaticus] Length = 288 Score = 78.8 bits (191), Expect = 1e-13 Identities = 71/248 (28%), Positives = 112/248 (44%), Gaps = 20/248 (8%) Query: 48 EVQGVKAYKSVKDIPG--EVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEE 105 EV GV Y +VK+ EVD +II VP D ++ G+ +V+IT G Sbjct: 46 EVLGVPVYDTVKEAVAHHEVDASIIFVPAPAAADAALEAAHAGIPLIVLITEGIPTL--- 102 Query: 106 GKKEEKELVEIAHRYGMRIIGPNCVGIMNTH-ADLNATFITVAKKGNVAFISQSGALGAG 164 + VE G R+IG NC GI++ H + V K+G V IS+SG L Sbjct: 103 ---DMVRAVEEIKALGSRLIGGNCPGIISAHLPKIGIMPGHVFKRGRVGIISRSGTLRHE 159 Query: 165 IVYKTIKEDIGFSKFISVGN--MADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEV 222 + +G + + +G + L F +L+ + E +A+ L G G E Sbjct: 160 AAAALSQAGLGTTTTVGIGGDPVRRLTFKDLLPLFNEDPETEAVVLI--GEIGGSDEEEA 217 Query: 223 AKRVT--KKKPVIALKAGKSESGARAASSHTGSL----AGSWKIYEAAFKQSGVLVANTI 276 A V KKPV+ G+S + H G++ G+ + AF ++G+ VA+TI Sbjct: 218 AAWVKDHMKKPVVGFIGGRSAPKGK-RMGHAGAIIMGNVGTPESKLRAFAEAGIPVADTI 276 Query: 277 DEMLSMAR 284 DE++ + + Sbjct: 277 DEIVELVK 284 >gi|11499134 succinyl-CoA synthetase, alpha subunit (sucD-1) [Archaeoglobus fulgidus] >gi|6647839|sp|O28733|SUD1_ARCFU SUCCINYL-COA SYNTHETASE ALPHA CHAIN 1 (SCS-ALPHA 1) >gi|7437884|pir||B69442 succinate--CoA ligase (ADP-forming) (EC 6.2.1.5) alpha-1 chain - Archaeoglobus fulgidus >gi|2649022|gb|AAB89707.1| (AE000996) succinyl-CoA synthetase, alpha subunit (sucD-1) [Archaeoglobus fulgidus] Length = 291 Score = 77.6 bits (188), Expect = 3e-13 Identities = 76/289 (26%), Positives = 133/289 (45%), Gaps = 31/289 (10%) Query: 9 KGIAVIGASNDPKKL---GYEVFKNLKQYKGGNVYPVNVREEEVQGVKAYKSVKDIPGEV 65 +GI S K++ G +V + KGG+ EV G+ Y +V++ E Sbjct: 17 QGITGFQGSFQAKRMLDYGTKVVGGVTPGKGGS---------EVHGIPVYNTVEEAVAET 67 Query: 66 --DLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRYGMR 123 D +II VP +F D + + + G++ VV +T G E ++L E+ Sbjct: 68 NADTSIIYVPARFATDAIFEAFDAGLRLVVCVTEGIPLYDE--MLIHRKLREVKSM---- 121 Query: 124 IIGPNCVGIMNT-HADLNATFITVAKKGNVAFISQSGALGAGIVYKTIKEDIGFSKFISV 182 ++GPNC G+++ + + +GN+ +S+SG L I K IG S + + Sbjct: 122 LLGPNCPGVISPGRSKVGLLPDRSFTQGNLGVVSRSGTLTYQICENLTKAGIGQSTVVGI 181 Query: 183 GN--MADLDFAELMEYLADTEEDKAIALYIE-GIRNGRKFIEVAKRVTKKKPVIALKAGK 239 G M L F ++++ + EE KA+ L E G K E K+++ KPV+A AG+ Sbjct: 182 GGDPMPGLTFVDVLKMFEEDEETKAVLLVGEIGGTAEEKAAEFIKQMS--KPVVAFIAGR 239 Query: 240 SESGARAASSHTGSL----AGSWKIYEAAFKQSGVLVANTIDEMLSMAR 284 + + H G++ G+ + AA + +G VA T+ +++ R Sbjct: 240 TAPPGK-RMGHAGAIIEGSTGTAEAKMAALRDAGARVAETLLDVVKEVR 287 >pir||F81399 succinate--CoA ligase (ADP-forming) (EC 6.2.1.5) alpha chain Cj0534 [imported] - Campylobacter jejuni (strain NCTC 11168) >gi|6968002|emb|CAB75170.1| (AL139075) succinyl-coA synthetase alpha chain [Campylobacter jejuni] Length = 289 Score = 77.6 bits (188), Expect = 3e-13 Identities = 71/251 (28%), Positives = 115/251 (45%), Gaps = 23/251 (9%) Query: 24 GYEVFKNLKQYKGGNVYPVN-VREEEVQGVKAYKSVKDIPGEVDLAIIVVPKKFVKDTLI 82 G + + +KGG + V + VKA K+ D+++I VP V D++I Sbjct: 32 GTNIVGGITPHKGGQTHLGKPVFDTVADAVKATKA--------DVSLIFVPAFAVGDSVI 83 Query: 83 QCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRYGMRIIGPNCVGIMNT-HADLNA 141 + + G+K V+IT K+ + A++ GM+IIGPNC GI+ + L Sbjct: 84 EAADAGIKLAVVITE------HTPVKDMMFAKQYANKKGMKIIGPNCPGIITSEECKLGI 137 Query: 142 TFITVAKKGNVAFISQSGALGAGIVYKTIKEDIGFSKFISVGN--MADLDFAELMEYLAD 199 + KKG V IS+SG L + ++ G S + +G + L + EL+ Sbjct: 138 MPGFIFKKGCVGLISKSGTLTYEAANQVVQGGYGISTAVGIGGDPIIGLAYKELLSEFQK 197 Query: 200 TEEDKAIALYIEGIRNGRKFIEVAKRVTK--KKPVIALKAGKSESGARAASSHTGSLAGS 257 +E KAI + G G +E AK + + KPV+A AG + + H G++ GS Sbjct: 198 DDETKAIVMI--GEIGGSLEVEAAKFIKENISKPVVAFIAGATAPKGK-RMGHAGAIVGS 254 Query: 258 WKIYEAAFKQS 268 AA K++ Sbjct: 255 ADESAAAKKEA 265 >emb|CAB92672.1| (AL356832) succinyl CoA synthetase alpha chain [Streptomyces coelicolor A3(2)] Length = 294 Score = 74.9 bits (181), Expect = 2e-12 Identities = 80/292 (27%), Positives = 125/292 (42%), Gaps = 49/292 (16%) Query: 10 GIAVIGASNDPKKLGYEVFKNLKQYKGGNVYPVNVREEEVQGVKAYKSVKDIPGEVDLAI 69 G V+G N P+K G V + G V +E ++ A ++++ Sbjct: 32 GTEVVGGVN-PRKAGTSV-----DFDGNEVPVFGTVKEAIEKTGA-----------NVSV 74 Query: 70 IVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGE------EGKKEEKELVEIAHRYGMR 123 I VP+KF KD +++ + + V+IT G GKK K R Sbjct: 75 IFVPEKFTKDAVVEAIDAEIPLAVVITEGIAVHDSAAFWSYAGKKGNK----------TR 124 Query: 124 IIGPNCVGIMNTHADLNATFI--TVAKKGNVAFISQSGALGAGIVYKTIKEDIGFSKFIS 181 IIGPNC GI+ T N I + K G + +S+SG L ++Y+ DIGFS + Sbjct: 125 IIGPNCPGII-TPGQSNVGIIPGDITKPGRIGLVSKSGTLTYQMMYEL--RDIGFSTAVG 181 Query: 182 VGN---MADLDFAELMEYLADTEEDKAIAL-YIEGIRNGRKFIEVAKRVTKKKPVIALKA 237 +G + L + AD E D + + I G R ++K VT KPV+ A Sbjct: 182 IGGDPIIGTTHIDALAAFEADPETDLIVMIGEIGGDAEERAAEYISKNVT--KPVVGYVA 239 Query: 238 GKSESGARAASSHTGSL----AGSWKIYEAAFKQSGVLVANTIDEMLSMARA 285 G + + H G++ +G+ + + A + +GV V T E +ARA Sbjct: 240 GFTAPEGK-TMGHAGAIVSGSSGTAQAKKEALEAAGVKVGKTPTETAKLARA 290 >sp|P09143|SUCD_THEFL SUCCINYL-COA SYNTHETASE ALPHA CHAIN (SCS-ALPHA) >gi|68575|pir||SYTWSA succinate--CoA ligase (ADP-forming) (EC 6.2.1.5) alpha chain [validated] - Thermus aquaticus >gi|48178|emb|CAA38007.1| (X54073) succinate--CoA ligase (ADP-forming) [Thermus aquaticus flavus] >gi|581794|emb|CAA39507.1| (X56033) succinyl-CoA synthetase [Thermus aquaticus] >gi|581798|emb|CAA31303.1| (X12815) succinyl-CoA synthetase alpha-subunit (AA 1-288) [Thermus aquaticus] >gi|227823|prf||1712304D succinyl CoA synthetase:SUBUNIT=alpha [Thermus aquaticus flavus] Length = 288 Score = 74.5 bits (180), Expect = 2e-12 Identities = 69/248 (27%), Positives = 110/248 (43%), Gaps = 20/248 (8%) Query: 48 EVQGVKAYKSVKDIPG--EVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEE 105 EV GV Y +VK+ EVD +II VP D ++ G+ +V+IT G Sbjct: 46 EVLGVPVYDTVKEAVAHHEVDASIIFVPAPAAADAALEAAHAGIPLIVLITEGIPTL--- 102 Query: 106 GKKEEKELVEIAHRYGMRIIGPNCVGIMNT-HADLNATFITVAKKGNVAFISQSGALGAG 164 + VE G R+IG NC GI++ + V K+G V IS+SG L Sbjct: 103 ---DMVRAVEEIKALGSRLIGGNCPGIISAEETKIGIMPGHVFKRGRVGIISRSGTLTYE 159 Query: 165 IVYKTIKEDIGFSKFISVGN--MADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEV 222 + +G + + +G + F +L+ + E +A+ L G G E Sbjct: 160 AAAALSQAGLGTTTTVGIGGDPVIGTTFKDLLPLFNEDPETEAVVLI--GEIGGSDEEEA 217 Query: 223 AKRVT--KKKPVIALKAGKSESGARAASSHTGSL----AGSWKIYEAAFKQSGVLVANTI 276 A V KKPV+ G+S + H G++ G+ + AF ++G+ VA+TI Sbjct: 218 AAWVKDHMKKPVVGFIGGRSAPKGK-RMGHAGAIIMGNVGTPESKLRAFAEAGIPVADTI 276 Query: 277 DEMLSMAR 284 DE++ + + Sbjct: 277 DEIVELVK 284 >prf||1708208A succinyl CoA synthetase [Thermus aquaticus] Length = 288 Score = 74.5 bits (180), Expect = 2e-12 Identities = 69/248 (27%), Positives = 110/248 (43%), Gaps = 20/248 (8%) Query: 48 EVQGVKAYKSVKDIPG--EVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEE 105 EV GV Y +VK+ EVD +II VP D ++ G+ +V+IT G Sbjct: 46 EVLGVPVYDTVKEAVAHHEVDASIIFVPAPAAADAALEAAHAGIPLIVLITEGIPTL--- 102 Query: 106 GKKEEKELVEIAHRYGMRIIGPNCVGIMNT-HADLNATFITVAKKGNVAFISQSGALGAG 164 + VE G R+IG NC GI++ + V K+G V IS+SG L Sbjct: 103 ---DMVRAVEEIKALGSRLIGGNCPGIISAEETKIGIMPGHVFKRGRVGIISRSGTLTYE 159 Query: 165 IVYKTIKEDIGFSKFISVGN--MADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEV 222 + +G + + +G + F +L+ + E +A+ L G G E Sbjct: 160 AAAALSQAGLGTTTTVGIGGDPVIGTTFKDLLPLFNEDPETEAVVLI--GEIGGSDEEEA 217 Query: 223 AKRVT--KKKPVIALKAGKSESGARAASSHTGSL----AGSWKIYEAAFKQSGVLVANTI 276 A V KKPV+ G+S + H G++ G+ + AF ++G+ VA+TI Sbjct: 218 AAWVKDHMKKPVVGFIGGRSAPKGK-RMGHAGAIIMGNVGTPESKLRAFAEAGIPVADTI 276 Query: 277 DEMLSMAR 284 DE++ + + Sbjct: 277 DEIVELVK 284 >prf||1414360A succinyl-CoA synthetase alpha [Thermus aquaticus] Length = 288 Score = 73.4 bits (177), Expect = 5e-12 Identities = 69/248 (27%), Positives = 110/248 (43%), Gaps = 20/248 (8%) Query: 48 EVQGVKAYKSVKDIPG--EVDLAIIVVPKKFVKDTLIQCGEKGVKGVVIITAGFGETGEE 105 EV GV Y +VK+ EVD +II VP D ++ G+ +V+IT G Sbjct: 46 EVLGVPVYDTVKEAVAHHEVDASIIFVPAPAAADAALEAAHAGIPLIVLITEGIPTL--- 102 Query: 106 GKKEEKELVEIAHRYGMRIIGPNCVGIMNT-HADLNATFITVAKKGNVAFISQSGALGAG 164 + VE G R+IG NC GI++ + V K+G V IS+SG L Sbjct: 103 ---DMVRAVEEIKALGSRLIGGNCPGIISAEETKIGIMPGHVFKRGRVGIISRSGTLTYE 159 Query: 165 IVYKTIKEDIGFSKFISVGN--MADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEV 222 + +G + + +G + F +L+ + E +A+ L G G E Sbjct: 160 AAAALSQAGLGTTTTVGIGGDPVITGTFKDLLPLFNEDPETEAVVLI--GEIGGSDEEEA 217 Query: 223 AKRVT--KKKPVIALKAGKSESGARAASSHTGSL----AGSWKIYEAAFKQSGVLVANTI 276 A V KKPV+ G+S + H G++ G+ + AF ++G+ VA+TI Sbjct: 218 AAWVKDHMKKPVVGFIGGRSAPKGK-RMGHAGAIIMGNVGTPESKLRAFAEAGIPVADTI 276 Query: 277 DEMLSMAR 284 DE++ + + Sbjct: 277 DEIVELVK 284 >pir||F81180 conserved hypothetical protein NMB0593 [imported] - Neisseria meningitidis (group B strain MD58) >gi|7225823|gb|AAF41021.1| (AE002415) conserved hypothetical protein [Neisseria meningitidis MC58] Length = 808 Score = 72.2 bits (174), Expect = 1e-11 Identities = 74/302 (24%), Positives = 124/302 (40%), Gaps = 20/302 (6%) Query: 4 YFFNPKGIAVIGASNDPKKLGYEVFKNLKQYK-GGNVYPVNVREEEVQGVKAYKSVKDIP 62 YFF P I +IGAS P LG V NL G + PVN R + G+ AY S+ IP Sbjct: 9 YFFMPNHIILIGASEQPYSLGERVLSNLLSTPFQGKITPVNPRHHTIAGLPAYTSLNKIP 68 Query: 63 GEVDLAI-IVVPKKFVKDTLIQ-CGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRY 120 G DL I + +P + DTL + C +K ++ +++I + E E + H Sbjct: 69 GNADLIIAVTLPDSY--DTLFKTCRKKQLRHIILIQDWDNLSAAELHTAE-TAIRKHHGN 125 Query: 121 GMRIIGPNCVGIMNTHADLNATFITVAKKGNVAFISQSGALGAGIVYKTIKEDIGFSKFI 180 G+ I GI LN + G+ A ++ + A+ I K G S+ I Sbjct: 126 GLNITACTTAGIQLPSLGLNISTQDGYAAGHTAILTGNAAVSRQIDNILNKLRQGTSRHI 185 Query: 181 SV-GNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKAGK 239 S+ ++ + A+ + + K L+ + RK ++ T+ P+I + Sbjct: 186 SLHPGISPITSADWLNRFGHSLHTKTAVLHHNPEEDQRKLFSAIRQFTRHTPLILHITCR 245 Query: 240 SESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQPLPRGKRVAIM 299 + RA + + LV+ D++ + RA LP R+ I+ Sbjct: 246 TTETDRA-------------VLHCLARHCNFLVSFNADDLEAALRAQLSDLPPLSRLDIL 292 Query: 300 TN 301 ++ Sbjct: 293 SD 294 >pir||D81924 hypothetical protein NMA0796 [imported] - Neisseria meningitidis (group A strain Z2491) >gi|7379516|emb|CAB84079.1| (AL162754) hypothetical protein NMA0796 [Neisseria meningitidis Z2491] Length = 808 Score = 70.2 bits (169), Expect = 4e-11 Identities = 73/302 (24%), Positives = 123/302 (40%), Gaps = 20/302 (6%) Query: 4 YFFNPKGIAVIGASNDPKKLGYEVFKNLKQYK-GGNVYPVNVREEEVQGVKAYKSVKDIP 62 YFF P I +IGAS P LG V NL G + PVN R + G+ AY S+ IP Sbjct: 9 YFFMPNHIILIGASERPYSLGERVLSNLLSTPFQGKITPVNPRHHTIAGLPAYTSLNKIP 68 Query: 63 GEVDLAI-IVVPKKFVKDTLIQ-CGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRY 120 G DL I + +P + DTL + C +K ++ +++I E E + H Sbjct: 69 GNADLIIAVTLPDSY--DTLFKTCRKKQLRHIILIQDWDSLPAAELHTAE-TAIRKHHGN 125 Query: 121 GMRIIGPNCVGIMNTHADLNATFITVAKKGNVAFISQSGALGAGIVYKTIKEDIGFSKFI 180 G+ I GI LN + G+ A ++ + A+ I K G S+ I Sbjct: 126 GLNITACTTAGIQLPSLGLNISTQDGYAAGHTAILTGNAAVSRQIDNILNKLRQGTSRHI 185 Query: 181 SV-GNMADLDFAELMEYLADTEEDKAIALYIEGIRNGRKFIEVAKRVTKKKPVIALKAGK 239 S+ ++ + A+ + + K L+ + RK ++ T+ P+I + Sbjct: 186 SLHPGISPITSADWLNRFGHSLHTKTAVLHHNPEEDQRKLFSAIRQFTRHTPLILHITCR 245 Query: 240 SESGARAASSHTGSLAGSWKIYEAAFKQSGVLVANTIDEMLSMARAFTQPLPRGKRVAIM 299 + RA + + L++ D++ + RA LP R+ I+ Sbjct: 246 TTETDRA-------------VLHCLARHCNFLISFNADDLEAALRAQLSDLPPLSRLDIL 292 Query: 300 TN 301 ++ Sbjct: 293 SD 294 >emb|CAC12452.1| (AL445067) probable succinyl-CoA synthetase, alpha subunit [Thermoplasma acidophilum] Length = 294 Score = 69.9 bits (168), Expect = 6e-11 Identities = 74/262 (28%), Positives = 119/262 (45%), Gaps = 25/262 (9%) Query: 22 KLGYEVFKNLKQYKGGNVYPVNVREEEVQGVKAYKSVKD-IPGEVDLAIIVVPKKFVKDT 80 K G +V + KGG + V SV + + E D +I VP +VKD Sbjct: 38 KFGTKVVAGIAPGKGGTKF--------ADKVPIVNSVSEAMQYEPDATMISVPAPYVKDA 89 Query: 81 LIQCGEKGVKGVVIITAGFGETGEEGKKEEKELVEIAHRYGMRIIGPNCVGI-MNTHADL 139 + + G+K V I+T ++ E+V+ A G+ ++GPN GI + + + Sbjct: 90 AYEAIDNGLKIVYILTE------HVPYQDTMEIVKEASLRGITVLGPNGPGITVPFESKI 143 Query: 140 NATFITVAKKGNVAFISQSGALGAGIVYKTIKEDIGFSKFISVG--NMADLDFAELMEYL 197 + K+G+VA S+SG L IVY K +G S I +G + L F ++++ Sbjct: 144 GIMPNHIFKEGDVAIASRSGTLTYEIVYAVTKAGMGESTVIGLGGDRVVGLTFIDVLKMF 203 Query: 198 ADTEEDKAIALYIE-GIRNGRKFIEVAKRVTKKKPVIALKAGKSESGARAASSHTGSL-- 254 E+ K I L E G N + K+ KKK V+A AG+S + H G++ Sbjct: 204 EKDEKTKRIVLVGEIGGNNEELAADYIKKHVKKK-VVAYIAGRSAPPGK-RMGHAGAIIE 261 Query: 255 --AGSWKIYEAAFKQSGVLVAN 274 G+ + AF ++GV VA+ Sbjct: 262 RGVGTAESKLKAFAEAGVKVAD 283 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.316 0.135 0.375 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 164372560 Number of Sequences: 2977 Number of extensions: 7050553 Number of successful extensions: 20309 Number of sequences better than 1.0e-10: 44 Number of HSP's better than 0.0 without gapping: 29 Number of HSP's successfully gapped in prelim test: 15 Number of HSP's that attempted gapping in prelim test: 20118 Number of HSP's gapped (non-prelim): 47 length of query: 457 length of database: 189,106,746 effective HSP length: 60 effective length of query: 397 effective length of database: 153,197,526 effective search space: 60819417822 effective search space used: 60819417822 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.6 bits) S2: 166 (69.1 bits)