BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0868 (hypE) DE:hydrogenase expression/formation protein
(hypE)
(336 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||E75040 hydrogenase expression/formation protein (hype) PAB0... 663 0.0
pir||D71121 probable hydrogenase expression/formation protein - ... 616 e-175
pir||B69125 hydrogenase expression/formation protein HypE - Meth... 386 e-106
sp|Q58089|Y676_METJA PUTATIVE HYDROGENASE EXPRESSION/FORMATION P... 385 e-106
emb|CAA51035.1| (X72294) ORF9 [Azotobacter vinelandii] 278 6e-74
sp|P40595|HYPE_AZOVI HYDROGENASE EXPRESSION/FORMATION PROTEIN HY... 278 6e-74
sp|P31906|HYPE_BRAJA HYDROGENASE EXPRESSION/FORMATION PROTEIN HYPE 278 7e-74
pir||S35767 hypothetical protein 9 - Azotobacter vinelandii 277 1e-73
sp|P40599|HYPE_RHILV HYDROGENASE EXPRESSION/FORMATION PROTEIN HY... 277 2e-73
sp|P42034|HUPE_AZOCH HYDROGENASE EXPRESSION/FORMATION PROTEIN HU... 276 2e-73
sp|P31905|HYPE_ALCEU HYDROGENASE EXPRESSION/FORMATION PROTEIN HY... 272 3e-72
pir||S35230 hypE protein - Bradyrhizobium japonicum >gi|39536|em... 268 5e-71
pir||A70388 hydrogenase expression/formation protein - Aquifex a... 268 6e-71
gi|11498961 hydrogenase expression/formation protein (hypE) [Arc... 265 6e-70
gb|AAB64436.1| (AF006594) HupE [Anabaena PCC7120] 259 3e-68
sp|P26412|HYPE_RHOCA HYDROGENASE EXPRESSION/FORMATION PROTEIN HY... 239 4e-62
pir||S77375 hydrogenase expression/formation protein hypE - Syne... 228 1e-58
gb|AAC26158.1| (AF035751) HypE [Synechococcus PCC7002] 227 1e-58
pir||S21906 hypE protein - Rhodobacter capsulatus >gi|46056|emb|... 226 3e-58
sp|P24193|HYPE_ECOLI HYDROGENASE ISOENZYMES FORMATION PROTEIN HY... 214 1e-54
gb|AAA69240.1| (U29579) CG Site no. 33119; ORF_o322 [Escherichia... 211 8e-54
pir||A81411 hydrogenase isoenzymes formation protein Cj0626 [imp... 195 7e-49
pir||G64525 hydrogenase expression/formation protein - Helicobac... 191 1e-47
pir||F71981 hydrogenase expression/formation protein - Helicobac... 190 2e-47
pir||F75178 hydrogenase expression/formation related protein PAB... 95 1e-18
pir||E71035 probable hydrogenase expression/formation protein - ... 92 8e-18
gb|AAK42820.1| Hydrogenase expression/formation factor related p... 83 5e-15
sp|O27427|PURL_METTH PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE ... 81 2e-14
sp|O59497|THIL_PYRHO PROBABLE THIAMINE-MONOPHOSPHATE KINASE (THI... 80 3e-14
pir||H75153 thiamin monophosphate kinase (thil) PAB2358 - Pyroco... 80 3e-14
gb|AAG18782.1| (AE004983) hydrogenase expression/formation; Hef ... 78 1e-13
pir||A75026 phosphoribosylformylglycinamidine synthase II (purl)... 75 1e-12
pir||G64476 hypothetical protein MJ1416 - Methanococcus jannasch... 74 2e-12
pir||F72508 probable hydrogenase expression/formation protein AP... 74 3e-12
gb|AAK40418.1| Hydrogenase expression/formation protein (hypE) [... 72 1e-11
pir||S75435 hypothetical protein c05018 - Sulfolobus solfataricu... 72 1e-11
emb|CAC12402.1| (AL445067) hydrogenase expression/formation prot... 72 1e-11
sp|Q58660|PURL_METJA PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE ... 71 2e-11
pir||A71211 probable phosphoribosylformylglycinamidine synthase ... 69 9e-11
>pir||E75040 hydrogenase expression/formation protein (hype) PAB0868 -
Pyrococcus abyssi (strain Orsay)
>gi|5458731|emb|CAB50218.1| (AJ248287) hydrogenase
expression/formation protein (hypE) [Pyrococcus abyssi]
Length = 336
Score = 663 bits (1692), Expect = 0.0
Identities = 336/336 (100%), Positives = 336/336 (100%)
Query: 1 MKIRLEHGAGGELMEELIRDVILKNLTLNSAGGIGLEALDDGATIPIDGRHIVFTIDGHT 60
MKIRLEHGAGGELMEELIRDVILKNLTLNSAGGIGLEALDDGATIPIDGRHIVFTIDGHT
Sbjct: 1 MKIRLEHGAGGELMEELIRDVILKNLTLNSAGGIGLEALDDGATIPIDGRHIVFTIDGHT 60
Query: 61 VKPLFFPGGDIGRLAVSGTVNDLAVMGAKPIALASSLIIGEGFDSQDLERILKSMDETAK 120
VKPLFFPGGDIGRLAVSGTVNDLAVMGAKPIALASSLIIGEGFDSQDLERILKSMDETAK
Sbjct: 61 VKPLFFPGGDIGRLAVSGTVNDLAVMGAKPIALASSLIIGEGFDSQDLERILKSMDETAK 120
Query: 121 EVPVPIVTGDTKVVEENVGIFVITAGIGIAEKPISDAGAKVGDAVLVSGTIGDHGIALMS 180
EVPVPIVTGDTKVVEENVGIFVITAGIGIAEKPISDAGAKVGDAVLVSGTIGDHGIALMS
Sbjct: 121 EVPVPIVTGDTKVVEENVGIFVITAGIGIAEKPISDAGAKVGDAVLVSGTIGDHGIALMS 180
Query: 181 HREGISFETELKSDVAPTWDVVKAVADAIGWENIHAMKDPTRGGLSNALNEMARKANVGI 240
HREGISFETELKSDVAPTWDVVKAVADAIGWENIHAMKDPTRGGLSNALNEMARKANVGI
Sbjct: 181 HREGISFETELKSDVAPTWDVVKAVADAIGWENIHAMKDPTRGGLSNALNEMARKANVGI 240
Query: 241 LIKESEIPIRPEVKAASEMLGISPYEVANEGKVVMIVEREYAEEALEAMRKTEKGRNAAI 300
LIKESEIPIRPEVKAASEMLGISPYEVANEGKVVMIVEREYAEEALEAMRKTEKGRNAAI
Sbjct: 241 LIKESEIPIRPEVKAASEMLGISPYEVANEGKVVMIVEREYAEEALEAMRKTEKGRNAAI 300
Query: 301 IGEVIKDYPGKVILETGIGGKRFLEPPIGDPVPRVC 336
IGEVIKDYPGKVILETGIGGKRFLEPPIGDPVPRVC
Sbjct: 301 IGEVIKDYPGKVILETGIGGKRFLEPPIGDPVPRVC 336
>pir||D71121 probable hydrogenase expression/formation protein - Pyrococcus
horikoshii >gi|3257147|dbj|BAA29830.1| (AP000003) 336aa
long hypothetical hydrogenase expression/formation
protein [Pyrococcus horikoshii]
Length = 336
Score = 616 bits (1571), Expect = e-175
Identities = 301/336 (89%), Positives = 326/336 (96%)
Query: 1 MKIRLEHGAGGELMEELIRDVILKNLTLNSAGGIGLEALDDGATIPIDGRHIVFTIDGHT 60
MKI+LEHGAGGELMEELIRDVILKNLTLNSAGGIGLEALDDGATIP +G+H+VFTIDGHT
Sbjct: 1 MKIKLEHGAGGELMEELIRDVILKNLTLNSAGGIGLEALDDGATIPFEGKHLVFTIDGHT 60
Query: 61 VKPLFFPGGDIGRLAVSGTVNDLAVMGAKPIALASSLIIGEGFDSQDLERILKSMDETAK 120
V+PLFFPGGDIGRLAVSGTVNDLAVMGAKP+ALASSLIIGEGFDS LE ILKSM+ TAK
Sbjct: 61 VRPLFFPGGDIGRLAVSGTVNDLAVMGAKPLALASSLIIGEGFDSDKLEEILKSMNRTAK 120
Query: 121 EVPVPIVTGDTKVVEENVGIFVITAGIGIAEKPISDAGAKVGDAVLVSGTIGDHGIALMS 180
EVPVPI+TGDTKVVE+N+ IFVITAGIGIAEKPISDAGAKVGD VLV+GTIGDHGIALMS
Sbjct: 121 EVPVPIITGDTKVVEDNIEIFVITAGIGIAEKPISDAGAKVGDLVLVNGTIGDHGIALMS 180
Query: 181 HREGISFETELKSDVAPTWDVVKAVADAIGWENIHAMKDPTRGGLSNALNEMARKANVGI 240
HREGISFETELKSDVAP WDVVK VADAIGWENIHAMKDPTRGGLSNALNEMARKA+VGI
Sbjct: 181 HREGISFETELKSDVAPIWDVVKTVADAIGWENIHAMKDPTRGGLSNALNEMARKADVGI 240
Query: 241 LIKESEIPIRPEVKAASEMLGISPYEVANEGKVVMIVEREYAEEALEAMRKTEKGRNAAI 300
L++ES+IPIRPEVKAA +MLGISPY+VANEGKV+M+V+REYAE+ALEAMRKTEKG++AAI
Sbjct: 241 LVRESDIPIRPEVKAAGDMLGISPYDVANEGKVIMVVDREYAEDALEAMRKTEKGKDAAI 300
Query: 301 IGEVIKDYPGKVILETGIGGKRFLEPPIGDPVPRVC 336
IGE+IKDYPGKVILETGIGG+RFLEPPIGDPVPRVC
Sbjct: 301 IGEIIKDYPGKVILETGIGGRRFLEPPIGDPVPRVC 336
>pir||B69125 hydrogenase expression/formation protein HypE - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2621250|gb|AAB84711.1| (AE000807) hydrogenase
expression/formation protein HypE [Methanobacterium
thermoautotrophicum]
Length = 376
Score = 386 bits (982), Expect = e-106
Identities = 192/341 (56%), Positives = 256/341 (74%), Gaps = 10/341 (2%)
Query: 1 MKIRLEHGAGGELMEELIRDVILKNL-TLNSAGGIGLEALDDGATIPIDGRHIVFTIDGH 59
MKI + HGAGGE+M++LI D+IL N+ GG+GLE LDDGA+IP+ IV + DGH
Sbjct: 41 MKIGMSHGAGGEVMQDLISDIILSNIHNTRVNGGVGLEDLDDGASIPLGDYEIVISTDGH 100
Query: 60 TVKPLFFPGGDIGRLAVSGTVNDLAVMGAKPIALASSLIIGEGFDSQDLERILKSMDETA 119
T+ PLFFPGGDIGR+AV+GTVND++VMGA+P+A+A+++II EGF +DLERI+KSMD +
Sbjct: 101 TIDPLFFPGGDIGRIAVAGTVNDISVMGARPLAIANAMIISEGFPGEDLERIIKSMDAVS 160
Query: 120 KEVPVPIVTGDTKVVEENV--GIFVITAGIGIAEK--PISDAGAKVGDAVLVSGTIGDHG 175
+E V IVTGDTKV+E+ + + T GIG+ + + D+G + GD ++++G++GDHG
Sbjct: 161 RETGVSIVTGDTKVMEQGKLDRMVITTTGIGVVGRGETVRDSGLRPGDKIILTGSVGDHG 220
Query: 176 IALMSHREGISFETELKSDVAPTWDVVKAVADAIGWENIHAMKDPTRGGLSNALNEMARK 235
+ALM+ REG F+T+L+SDVAP W +V+A + G + AMKDPTRGG++NALNEMA K
Sbjct: 221 MALMAFREGFGFDTDLESDVAPVWGIVEAALNVGG---VTAMKDPTRGGIANALNEMADK 277
Query: 236 ANVGILIKESEIPIRPEVKAASEMLGISPYEVANEGKVVMIVEREYAEEALEAMRKTEKG 295
+ VG+++ E IP+R EVKA SEMLGI PYEVANEGKV++ V+ EYAE+ L A+R G
Sbjct: 278 SGVGMVLDEDSIPVREEVKAVSEMLGIDPYEVANEGKVIIGVDPEYAEDVLAAVRSAPYG 337
Query: 296 RNAAIIGEVIKDYPGKVILETGIGGKRFLEPPIGDPVPRVC 336
A IIGEV D VILET +GG+R LE P+ DPVPRVC
Sbjct: 338 EEARIIGEVTDD--KHVILETSLGGRRILEAPVADPVPRVC 376
>sp|Q58089|Y676_METJA PUTATIVE HYDROGENASE EXPRESSION/FORMATION PROTEIN MJ0676
>gi|2127980|pir||D64384 hydrogenase expression/formation
protein homolog - Methanococcus jannaschii
>gi|1591391|gb|AAB98671.1| (U67515) hydrogenase
expression/formation protein (hypE) [Methanococcus
jannaschii]
Length = 335
Score = 385 bits (979), Expect = e-106
Identities = 202/339 (59%), Positives = 260/339 (76%), Gaps = 7/339 (2%)
Query: 1 MKIRLEHGAGGELMEELIRDVILKNLTLNSA-GGIGLEALDDGATIPIDGRHIVFTIDGH 59
MKI HGAGG++M+ELI+DVILKNL + S GGIGLE+LDD ATIPI + IVFT+DGH
Sbjct: 1 MKITRMHGAGGKVMQELIKDVILKNLEITSVNGGIGLESLDDSATIPIGDKEIVFTVDGH 60
Query: 60 TVKPLFFPGGDIGRLAVSGTVNDLAVMGAKPIALASSLIIGEGFDSQDLERILKSMDETA 119
TVKP+FFPGGDIGRLAVSGTVNDLAVMGAKP+AL+ SLII EGF+ +DLE+I+KS++ET+
Sbjct: 61 TVKPIFFPGGDIGRLAVSGTVNDLAVMGAKPLALSLSLIIPEGFNLEDLEKIVKSINETS 120
Query: 120 KEVPVPIVTGDTKVVEENVGIFVITAGIGIAE--KPISDAGAKVGDAVLVSGTIGDHGIA 177
KE V I+TGDTKV + I + TAGIGI + K I D + GDA++VSG IG+HG+A
Sbjct: 121 KEAEVAIITGDTKVSDGVDDIIISTAGIGIVDRGKAIRDCNVQEGDAIIVSGNIGEHGLA 180
Query: 178 LMSHREGISFETELKSDVAPTWDVVKAVADAIGWENIHAMKDPTRGGLSNALNEMARKAN 237
++ REG FET +KSDVAP +++ V + I+AMKDPTRGGL++ALNEMA K+N
Sbjct: 181 ILLSREGFDFETNIKSDVAPINKLIERVLEE--GIQINAMKDPTRGGLADALNEMAEKSN 238
Query: 238 VGILIKESEIPIRPEVKAASEMLGISPYEVANEGKVVMIVEREYAEEALEAMRKTEKGRN 297
+GI I E +IPI EV++ ++LG+ P +ANEGKVVM V++E AE LE +R+ G+N
Sbjct: 239 IGITIFEDKIPISDEVQSICDILGLDPLTIANEGKVVMAVKKEDAERCLEILREHPLGKN 298
Query: 298 AAIIGEVIKDYPGKVILETGIGGKRFLEPPIGDPVPRVC 336
A IIG K++ G VI+ET I G+R ++ PIGDP+PRVC
Sbjct: 299 AEIIGYATKEHKG-VIIET-IVGRRIVDMPIGDPIPRVC 335
>emb|CAA51035.1| (X72294) ORF9 [Azotobacter vinelandii]
Length = 341
Score = 278 bits (704), Expect = 6e-74
Identities = 149/338 (44%), Positives = 210/338 (62%), Gaps = 11/338 (3%)
Query: 3 IRLEHGAGGELMEELIRDVILKNLTLNSAGGIGLEALDDGATIPIDGRHIVFTIDGHTVK 62
+ + HG+GG M +LI ++ + L L+ +D A + +V D H +
Sbjct: 11 VEMVHGSGGRAMGQLIEELFARALRNE-----WLDQRNDQAQFELPPGRVVMATDSHVIS 65
Query: 63 PLFFPGGDIGRLAVSGTVNDLAVMGAKPIALASSLIIGEGFDSQDLERILKSMDETAKEV 122
PLFFPGGDIG LAV GT+ND+A+ GA+P LA+ I+ EGF DL RI++SM A+E
Sbjct: 66 PLFFPGGDIGSLAVHGTINDVAMAGARPCYLAAGFILEEGFPLADLARIVESMAAAAREA 125
Query: 123 PVPIVTGDTKVVEENVG--IFVITAGIGIAEKPISDAG--AKVGDAVLVSGTIGDHGIAL 178
VP+VTGDTKVVE G +F+ T G+G+ + +G A+ GD +L+SG+IGDHG+ +
Sbjct: 126 GVPVVTGDTKVVEHGKGDGVFITTTGVGVVPPGLHLSGDQARPGDRILLSGSIGDHGVTI 185
Query: 179 MSHREGISFETELKSDVAPTWDVVKAVADAIGWENIHAMKDPTRGGLSNALNEMARKANV 238
+S REG+ FE ++ SD +V A+ A+ I ++DPTRGGL N LNE+AR++ V
Sbjct: 186 LSLREGLGFEADIGSDSQALHGLVAAMLAAV--PEIRCLRDPTRGGLGNTLNELARQSGV 243
Query: 239 GILIKESEIPIRPEVKAASEMLGISPYEVANEGKVVMIVEREYAEEALEAMRKTEKGRNA 298
G+ + E IP+R V+AA E LG+ P VANEGK++ I E AE LEAMR +GR A
Sbjct: 244 GMQLVERAIPVREPVRAACEFLGLDPLYVANEGKLIAICAAERAERLLEAMRAHPQGREA 303
Query: 299 AIIGEVIKDYPGKVILETGIGGKRFLEPPIGDPVPRVC 336
AIIG V+ D V +ET GG R ++ G+ +PR+C
Sbjct: 304 AIIGTVVADEHRFVQMETPFGGSRMVDWLSGEQLPRIC 341
>sp|P40595|HYPE_AZOVI HYDROGENASE EXPRESSION/FORMATION PROTEIN HYPE
>gi|628532|pir||S43354 hypE protein - Azotobacter
vinelandii >gi|398012|gb|AAA19513.1| (L23970) hypE
[Azotobacter vinelandii]
Length = 341
Score = 278 bits (704), Expect = 6e-74
Identities = 149/338 (44%), Positives = 210/338 (62%), Gaps = 11/338 (3%)
Query: 3 IRLEHGAGGELMEELIRDVILKNLTLNSAGGIGLEALDDGATIPIDGRHIVFTIDGHTVK 62
+ + HG+GG M +LI ++ + L L+ +D A + +V D H +
Sbjct: 11 VEMVHGSGGRAMGQLIEELFARALRNE-----WLDQRNDQAQFELPPGRVVMATDSHVIS 65
Query: 63 PLFFPGGDIGRLAVSGTVNDLAVMGAKPIALASSLIIGEGFDSQDLERILKSMDETAKEV 122
PLFFPGGDIG LAV GT+ND+A+ GA+P LA+ I+ EGF DL RI++SM A+E
Sbjct: 66 PLFFPGGDIGSLAVHGTINDVAMAGARPCYLAAGFILEEGFPLADLARIVESMAAAAREA 125
Query: 123 PVPIVTGDTKVVEENVG--IFVITAGIGIAEKPISDAG--AKVGDAVLVSGTIGDHGIAL 178
VP+VTGDTKVVE G +F+ T G+G+ + +G A+ GD +L+SG+IGDHG+ +
Sbjct: 126 GVPVVTGDTKVVEHGKGDGVFITTTGVGVVPPGLHLSGDQARPGDRILLSGSIGDHGVTI 185
Query: 179 MSHREGISFETELKSDVAPTWDVVKAVADAIGWENIHAMKDPTRGGLSNALNEMARKANV 238
+S REG+ FE ++ SD +V A+ A+ I ++DPTRGGL N LNE+AR++ V
Sbjct: 186 LSLREGLGFEADIGSDSQALHGLVAAMLAAV--PEIRCLRDPTRGGLGNTLNELARQSGV 243
Query: 239 GILIKESEIPIRPEVKAASEMLGISPYEVANEGKVVMIVEREYAEEALEAMRKTEKGRNA 298
G+ + E IP+R V+AA E LG+ P VANEGK++ I E AE LEAMR +GR A
Sbjct: 244 GMQLVERAIPVREPVRAACEFLGLDPLYVANEGKLIAICPAERAERLLEAMRAHPQGREA 303
Query: 299 AIIGEVIKDYPGKVILETGIGGKRFLEPPIGDPVPRVC 336
AIIG V+ D V +ET GG R ++ G+ +PR+C
Sbjct: 304 AIIGTVVADEHRFVQMETPFGGSRMVDWLSGEQLPRIC 341
>sp|P31906|HYPE_BRAJA HYDROGENASE EXPRESSION/FORMATION PROTEIN HYPE
Length = 346
Score = 278 bits (703), Expect = 7e-74
Identities = 156/338 (46%), Positives = 211/338 (62%), Gaps = 10/338 (2%)
Query: 3 IRLEHGAGGELMEELIRDVILKNLTLNSAGGIGLEALDDGATIPIDGRHIVFTIDGHTVK 62
+ L HG GG M +LI L + G L +D + + +V T DG+ V
Sbjct: 15 VDLSHGCGGRAMAQLI-----SGLFHEAFGNEWLARGNDQSAFDVRAGRMVMTTDGYVVS 69
Query: 63 PLFFPGGDIGRLAVSGTVNDLAVMGAKPIALASSLIIGEGFDSQDLERILKSMDETAKEV 122
PLFFPGG+IG LAV GTVND+A+ GAKP+ L++S II EGF DL+ I +SM A+E
Sbjct: 70 PLFFPGGNIGSLAVHGTVNDIAMAGAKPLYLSASFIIEEGFRFADLKLIAESMGAAAREA 129
Query: 123 PVPIVTGDTKVVEENV--GIFVITAGIGIAEK--PISDAGAKVGDAVLVSGTIGDHGIAL 178
V I+TGDTKVVE G+F+ TAG+G+ +S A+VGD VL+SGT+GDHG+A+
Sbjct: 130 DVHIITGDTKVVERGKADGLFISTAGVGVVPDGLDLSAEKARVGDRVLISGTLGDHGVAI 189
Query: 179 MSHREGISFETELKSDVAPTWDVVKAVADAIGWENIHAMKDPTRGGLSNALNEMARKANV 238
MS R+ ++FETE+ SD A D+V + A G I M+DPTRGGL+ LNE+A+++N+
Sbjct: 190 MSKRQNLAFETEIVSDSASLHDLVARMVQA-GGRGIRLMRDPTRGGLAATLNEIAQQSNL 248
Query: 239 GILIKESEIPIRPEVKAASEMLGISPYEVANEGKVVMIVEREYAEEALEAMRKTEKGRNA 298
G + E IP++P V AA E+LG+ P VANEGK+V IV E A L AMR GR+A
Sbjct: 249 GFHLLEEAIPVKPGVAAACELLGLDPLHVANEGKLVAIVAPEAAGAVLAAMRAHPLGRDA 308
Query: 299 AIIGEVIKDYPGKVILETGIGGKRFLEPPIGDPVPRVC 336
A IGE + D V + T GG R ++ G+ +PR+C
Sbjct: 309 ADIGEAVADDHHFVQMATSFGGGRIVDWLSGEQLPRIC 346
>pir||S35767 hypothetical protein 9 - Azotobacter vinelandii
Length = 329
Score = 277 bits (701), Expect = 1e-73
Identities = 149/334 (44%), Positives = 208/334 (61%), Gaps = 11/334 (3%)
Query: 7 HGAGGELMEELIRDVILKNLTLNSAGGIGLEALDDGATIPIDGRHIVFTIDGHTVKPLFF 66
HG+GG M +LI ++ + L L+ +D A + +V D H + PLFF
Sbjct: 3 HGSGGRAMGQLIEELFARALRNE-----WLDQRNDQAQFELPPGRVVMATDSHVISPLFF 57
Query: 67 PGGDIGRLAVSGTVNDLAVMGAKPIALASSLIIGEGFDSQDLERILKSMDETAKEVPVPI 126
PGGDIG LAV GT+ND+A+ GA+P LA+ I+ EGF DL RI++SM A+E VP+
Sbjct: 58 PGGDIGSLAVHGTINDVAMAGARPCYLAAGFILEEGFPLADLARIVESMAAAAREAGVPV 117
Query: 127 VTGDTKVVEENVG--IFVITAGIGIAEKPISDAG--AKVGDAVLVSGTIGDHGIALMSHR 182
VTGDTKVVE G +F+ T G+G+ + +G A+ GD +L+SG+IGDHG+ ++S R
Sbjct: 118 VTGDTKVVEHGKGDGVFITTTGVGVVPPGLHLSGDQARPGDRILLSGSIGDHGVTILSLR 177
Query: 183 EGISFETELKSDVAPTWDVVKAVADAIGWENIHAMKDPTRGGLSNALNEMARKANVGILI 242
EG+ FE ++ SD +V A+ A+ I ++DPTRGGL N LNE+AR++ VG+ +
Sbjct: 178 EGLGFEADIGSDSQALHGLVAAMLAAV--PEIRCLRDPTRGGLGNTLNELARQSGVGMQL 235
Query: 243 KESEIPIRPEVKAASEMLGISPYEVANEGKVVMIVEREYAEEALEAMRKTEKGRNAAIIG 302
E IP+R V+AA E LG+ P VANEGK++ I E AE LEAMR +GR AAIIG
Sbjct: 236 VERAIPVREPVRAACEFLGLDPLYVANEGKLIAICAAERAERLLEAMRAHPQGREAAIIG 295
Query: 303 EVIKDYPGKVILETGIGGKRFLEPPIGDPVPRVC 336
V+ D V +ET GG R ++ G+ +PR+C
Sbjct: 296 TVVADEHRFVQMETPFGGSRMVDWLSGEQLPRIC 329
>sp|P40599|HYPE_RHILV HYDROGENASE EXPRESSION/FORMATION PROTEIN HYPE
>gi|420901|pir||S32878 hydrogenase expression/formation
protein hypE [validated] - Rhizobium leguminosarum bv.
viciae >gi|48737|emb|CAA37164.1| (X52974) hydrophobic
protein [Rhizobium leguminosarum]
>gi|536795|emb|CAA85445.1| (Z36982) HYPE [Rhizobium
leguminosarum]
Length = 350
Score = 277 bits (700), Expect = 2e-73
Identities = 157/340 (46%), Positives = 214/340 (62%), Gaps = 12/340 (3%)
Query: 2 KIRLEHGAGGELMEELIRDVILKNLTLNSAGGIGLEALDDGATIPIDGRHIVFTIDGHTV 61
+I L HGAGG M +LI + K + L A +D + + G +V T DG+ V
Sbjct: 18 RIDLSHGAGGRAMGQLIEGIFHKAFDND-----WLRAGNDQSAFSVPGGRMVMTTDGYVV 72
Query: 62 KPLFFPGGDIGRLAVSGTVNDLAVMGAKPIALASSLIIGEGFDSQDLERILKSMDETAKE 121
PLFFPGG+IG LAV GT+ND+A+ GA P+ L++S II EGF DLERI SM ++E
Sbjct: 73 SPLFFPGGNIGTLAVHGTINDIAMAGAVPLYLSASFIIEEGFPLVDLERIADSMGAASRE 132
Query: 122 VPVPIVTGDTKVVEENV--GIFVITAGIGIAEKPI---SDAGAKVGDAVLVSGTIGDHGI 176
VPI+TGDTKVVE G+F+ TAGIG+A + SDA A+ GDAV++SG+IGDHG+
Sbjct: 133 AGVPIITGDTKVVERGKADGVFISTAGIGMAPDGLDLRSDA-ARPGDAVIISGSIGDHGV 191
Query: 177 ALMSHREGISFETELKSDVAPTWDVVKAVADAIGWENIHAMKDPTRGGLSNALNEMARKA 236
A+MS RE + F+T++ SD A +V + A G +I M+DPTRGG++ LNE+A ++
Sbjct: 192 AVMSKRENLEFDTDIVSDSAALHGLVADMV-AAGGAHIRLMRDPTRGGIAATLNEIASQS 250
Query: 237 NVGILIKESEIPIRPEVKAASEMLGISPYEVANEGKVVMIVEREYAEEALEAMRKTEKGR 296
VG I E IP++PEV AA E LG+ P VANEGK+V +V E A+ L A+ G
Sbjct: 251 RVGFRIDEEAIPMKPEVAAACEFLGLDPLNVANEGKLVAVVAPEGADAVLAAIHAHPLGA 310
Query: 297 NAAIIGEVIKDYPGKVILETGIGGKRFLEPPIGDPVPRVC 336
AA+IG V+ D V + T GG R ++ G+ +PR+C
Sbjct: 311 EAALIGHVVADDNYFVQMVTSFGGGRIVDWLSGEQLPRIC 350
>sp|P42034|HUPE_AZOCH HYDROGENASE EXPRESSION/FORMATION PROTEIN HUPE
>gi|2120753|pir||I39744 hydrogenase homolog 2 -
Azotobacter chroococcum >gi|142322|gb|AAA22137.1|
(M92282) hydrogenase-related protein [Azotobacter
chroococcum] >gi|382216|prf||1819270B hydrogenase
[Azotobacter chroococcum]
Length = 341
Score = 276 bits (699), Expect = 2e-73
Identities = 148/338 (43%), Positives = 211/338 (61%), Gaps = 11/338 (3%)
Query: 3 IRLEHGAGGELMEELIRDVILKNLTLNSAGGIGLEALDDGATIPIDGRHIVFTIDGHTVK 62
+ + HG+GG M +LI ++ + L L+ +D A + +V D H +
Sbjct: 11 VEMVHGSGGRAMGQLIEELFARALRNQ-----WLDQGNDQAQFELPPGRVVMATDSHVIS 65
Query: 63 PLFFPGGDIGRLAVSGTVNDLAVMGAKPIALASSLIIGEGFDSQDLERILKSMDETAKEV 122
PLFFPGGDIG LAV GT+ND+A+ GA+P LA+ I+ EGF DL RI++SM A+E
Sbjct: 66 PLFFPGGDIGSLAVHGTINDVAMAGARPCYLAAGFILEEGFPLADLARIVESMAAAAREA 125
Query: 123 PVPIVTGDTKVVEENVG--IFVITAGIGIAEKPISDAG--AKVGDAVLVSGTIGDHGIAL 178
VP+VTGDTKVVE G +F+ T G+G+ + +G A+ GD +L+SG+IGDHG+ +
Sbjct: 126 GVPVVTGDTKVVERGKGDGVFITTTGVGVVPPGLYLSGDRARPGDRILLSGSIGDHGVTI 185
Query: 179 MSHREGISFETELKSDVAPTWDVVKAVADAIGWENIHAMKDPTRGGLSNALNEMARKANV 238
+S REG+ FE ++ SD +V A+ +A+ I ++DPTRGGL N LNE+AR++ V
Sbjct: 186 LSLREGLGFEADIGSDSQALHGLVAAMVEAV--PEIRCLRDPTRGGLGNTLNELARQSGV 243
Query: 239 GILIKESEIPIRPEVKAASEMLGISPYEVANEGKVVMIVEREYAEEALEAMRKTEKGRNA 298
G+ + E IP+R V+AA E LG+ P VANEGK++ I E AE LE MR+ +GR A
Sbjct: 244 GMQLVERAIPLREPVRAACEFLGLDPLYVANEGKLIAICPAEQAERLLEVMREHPQGREA 303
Query: 299 AIIGEVIKDYPGKVILETGIGGKRFLEPPIGDPVPRVC 336
AIIG V+ D V +ET GG R ++ G+ +PR+C
Sbjct: 304 AIIGTVVADAQCFVQMETLFGGSRMVDWLNGEQLPRMC 341
>sp|P31905|HYPE_ALCEU HYDROGENASE EXPRESSION/FORMATION PROTEIN HYPE
>gi|321750|pir||S29979 hypE protein - Alcaligenes
eutrophus >gi|38776|emb|CAA49735.1| (X70183) HYPE
[Ralstonia eutropha]
Length = 351
Score = 272 bits (689), Expect = 3e-72
Identities = 151/342 (44%), Positives = 216/342 (63%), Gaps = 16/342 (4%)
Query: 2 KIRLEHGAGGELMEELIRDVILK---NLTLNSAGGIGLEALDDGATIPIDGRHIVFTIDG 58
+I + HGAGG +LI+++ + N L A+ GA +V D
Sbjct: 19 RIDMGHGAGGRAAAQLIQELFVAAFDNEWLRQGNDQAAFAMPAGA-------RMVMATDA 71
Query: 59 HTVKPLFFPGGDIGRLAVSGTVNDLAVMGAKPIALASSLIIGEGFDSQDLERILKSMDET 118
H V PLFFPGGDIG L+V GT+ND+A+ GAKP+ LA+S I+ EGF DL+RI++SM
Sbjct: 72 HVVSPLFFPGGDIGSLSVHGTINDVAMAGAKPLYLAASFILEEGFPLADLKRIVESMAGA 131
Query: 119 AKEVPVPIVTGDTKVVEENV--GIFVITAGIGI--AEKPISDAGAKVGDAVLVSGTIGDH 174
A+E VPIVTGDTKVVE+ G+F+ T G+G+ A I AGA+ GDA+L+SGT+G+H
Sbjct: 132 AREAGVPIVTGDTKVVEQGKGDGVFITTTGVGVVPAGILIDGAGARPGDAILLSGTMGEH 191
Query: 175 GIALMSHREGISFETELKSDVAPTWDVVKAVADAIGWENIHAMKDPTRGGLSNALNEMAR 234
G+A++S RE + F+TE++SD A D+V + + + ++DPTRGGL+ LNE++
Sbjct: 192 GVAILSKRESLEFDTEIRSDSAALHDLVAQMLAVV--PGVRVLRDPTRGGLATTLNEISS 249
Query: 235 KANVGILIKESEIPIRPEVKAASEMLGISPYEVANEGKVVMIVEREYAEEALEAMRKTEK 294
++ VG+++ E+ IP+ P+V AA E+LG+ P VANEGK+V I A+ L AMR
Sbjct: 250 QSGVGMVLDEAAIPVLPQVDAACELLGLDPLYVANEGKLVAICAAADADALLAAMRGHPL 309
Query: 295 GRNAAIIGEVIKDYPGKVILETGIGGKRFLEPPIGDPVPRVC 336
GR A IGEVI+D V + T GG R ++ G+ +PR+C
Sbjct: 310 GREARRIGEVIEDGRHFVQMRTKFGGMRVVDWLSGEQLPRIC 351
>pir||S35230 hypE protein - Bradyrhizobium japonicum >gi|39536|emb|CAA78989.1|
(Z17373) hypE [Bradyrhizobium japonicum]
>gi|448283|prf||1916405B hypE gene [Bradyrhizobium
japonicum]
Length = 321
Score = 268 bits (679), Expect = 5e-71
Identities = 148/319 (46%), Positives = 203/319 (63%), Gaps = 5/319 (1%)
Query: 22 ILKNLTLNSAGGIGLEALDDGATIPIDGRHIVFTIDGHTVKPLFFPGGDIGRLAVSGTVN 81
++ L + G L +D + + +V T DG+ V PLFFPGG+IG LAV GTVN
Sbjct: 4 LISGLFHEAFGNEWLARGNDQSAFDVRAGRMVMTTDGYVVSPLFFPGGNIGSLAVHGTVN 63
Query: 82 DLAVMGAKPIALASSLIIGEGFDSQDLERILKSMDETAKEVPVPIVTGDTKVVEENV--G 139
D+A+ GAKP+ L++S II EGF DL+ I +SM A+E V I+TGDTKVVE G
Sbjct: 64 DIAMAGAKPLYLSASFIIEEGFRFADLKLIAESMGAAAREADVHIITGDTKVVERGKADG 123
Query: 140 IFVITAGIGIAEK--PISDAGAKVGDAVLVSGTIGDHGIALMSHREGISFETELKSDVAP 197
+F+ TAG+G+ +S A+VGD VL+SGT+GDHG+A+MS R+ ++FETE+ SD A
Sbjct: 124 LFISTAGVGVVPDGLDLSAEKARVGDRVLISGTLGDHGVAIMSKRQNLAFETEIVSDSAS 183
Query: 198 TWDVVKAVADAIGWENIHAMKDPTRGGLSNALNEMARKANVGILIKESEIPIRPEVKAAS 257
D+V + A G I M+DPTRGGL+ LNE+A+++N+G + E IP++P V AA
Sbjct: 184 LHDLVARMVQA-GGRGIRLMRDPTRGGLAATLNEIAQQSNLGFHLLEEAIPVKPGVAAAC 242
Query: 258 EMLGISPYEVANEGKVVMIVEREYAEEALEAMRKTEKGRNAAIIGEVIKDYPGKVILETG 317
E+LG+ P VANEGK+V IV E A L AMR GR+AA IGE + D V + T
Sbjct: 243 ELLGLDPLHVANEGKLVAIVAPEAAGAVLAAMRAHPLGRDAADIGEAVADDHHFVQMATS 302
Query: 318 IGGKRFLEPPIGDPVPRVC 336
GG R ++ G+ +PR+C
Sbjct: 303 FGGGRIVDWLSGEQLPRIC 321
>pir||A70388 hydrogenase expression/formation protein - Aquifex aeolicus
>gi|2983521|gb|AAC07097.1| (AE000719) hydrogenase
expression/formation protein [Aquifex aeolicus]
Length = 332
Score = 268 bits (678), Expect = 6e-71
Identities = 140/338 (41%), Positives = 215/338 (63%), Gaps = 11/338 (3%)
Query: 2 KIRLEHGAGGELMEELIRDVILKNLTLNSAGGIGLEALDDGATIPIDGRHIVFTIDGHTV 61
KI L HG GGE ++LI+++ LK + L L+D + + + G+ + FT D TV
Sbjct: 3 KILLSHGGGGEETQKLIKNLFLKYFSNEI-----LNKLEDASLLNLSGK-VAFTTDAFTV 56
Query: 62 KPLFFPGGDIGRLAVSGTVNDLAVMGAKPIALASSLIIGEGFDSQDLERILKSMDETAKE 121
P+FF GGDIG+LAV+GTVNDL+VMGA+P L+ S +I EG ++LE ++KSM + A +
Sbjct: 57 SPIFFRGGDIGKLAVAGTVNDLSVMGARPKYLSVSFVIEEGLSFEELEEVVKSMAQEASK 116
Query: 122 VPVPIVTGDTKVVEENVG--IFVITAGIG-IAEKPISDAGAKVGDAVLVSGTIGDHGIAL 178
V IV GDTKVV + +F+ +GIG + + +S + G+ ++VSG++GDHG +
Sbjct: 117 TGVQIVAGDTKVVPKGQADKLFISASGIGEVVYEGLSAHNLREGNVIIVSGSVGDHGACI 176
Query: 179 MSHREGISFETELKSDVAPTWDVVKAVADAIGWENIHAMKDPTRGGLSNALNEMARKANV 238
++ REG+ FE ++SD W++++ V + +HA++D TRGGL+ LNE A ++ V
Sbjct: 177 LAQREGMEFEVPVESDCKSLWNMIEKVLSS--GAEVHAIRDATRGGLAGVLNEWAEQSKV 234
Query: 239 GILIKESEIPIRPEVKAASEMLGISPYEVANEGKVVMIVEREYAEEALEAMRKTEKGRNA 298
I ++E +IP++ V+ E+LG P +ANEG V V + A++ LE +R T +G+ A
Sbjct: 235 TIEVEEEKIPVKEAVRGLCELLGFEPTHLANEGMAVFAVASQDAQKVLEILRSTPEGKEA 294
Query: 299 AIIGEVIKDYPGKVILETGIGGKRFLEPPIGDPVPRVC 336
IIG+V+K KVIL T G KR +EPP G+ +PR+C
Sbjct: 295 QIIGKVVKKGEPKVILSTPYGVKRVMEPPAGELLPRIC 332
>gi|11498961 hydrogenase expression/formation protein (hypE) [Archaeoglobus
fulgidus] >gi|7447551|pir||D69420 hydrogenase
expression/formation protein (hypE) homolog -
Archaeoglobus fulgidus >gi|2649205|gb|AAB89877.1|
(AE001009) hydrogenase expression/formation protein
(hypE) [Archaeoglobus fulgidus]
Length = 344
Score = 265 bits (670), Expect = 6e-70
Identities = 156/352 (44%), Positives = 213/352 (60%), Gaps = 29/352 (8%)
Query: 3 IRLEHGAGGELMEELIRDVILKNLTLNSAGGIGLEALDDGATIPIDGRHIVFTIDGHTVK 62
IR E GAGG+ M EL++ + + + AG I LE ++D + D FT D + V
Sbjct: 4 IRKEDGAGGKYMVELLKKHVFPKIA-SRAGEIALEDMEDSSDFCDD---FAFTTDSYVVS 59
Query: 63 PLFFPGGDIGRLAVSGTVNDLAVMGAKPIALASSLIIGEGFDSQDLERILKSMDETAKEV 122
P F GG IG L+V GT NDLAVMGAKP ++ +L+I +GF D RI+ + ++ + V
Sbjct: 60 PPIFRGGSIGSLSVCGTSNDLAVMGAKPEFMSLALVIQDGFPLGDFRRIMDDIRDSVELV 119
Query: 123 PVPIVTGDTKVVEENVGIFVITAGIG---------------IAEKP---ISDAGAKVGDA 164
+ I+TGDTKVVE NVGI V TAGIG + + P + D G K GDA
Sbjct: 120 NLSIITGDTKVVESNVGIIVNTAGIGRRSEELERNLEVLRELRDYPYRWVRDKGLKEGDA 179
Query: 165 VLVSGTIGDHGIALMSHREGISFETELKSDVAPTWDVVKAVADAIGWENIHAMKDPTRGG 224
++VSG+I +H +M+ R G FE E KSDV P W V+ +A+ + AMKDPTRGG
Sbjct: 180 IIVSGSIAEHAAVIMAERMG--FEVEFKSDVYPVWLFVR---EALRRGGVTAMKDPTRGG 234
Query: 225 LSNALNEMARKANVGILIKESEIPIRPEVKAASEMLGISPYEVANEGKVVMIVEREYAEE 284
++ ALNEMA K+ VGI I E IP++ EV+ E+LG+ P +ANEGKVV V E A+E
Sbjct: 235 IAAALNEMAEKSGVGIKIFEERIPLKDEVRGLCELLGLDPLTMANEGKVVFGVHPEMADE 294
Query: 285 ALEAMRKTEKGRNAAIIGEVIKDYPGKVILETGIGGKRFLEPPIGDPVPRVC 336
L+A+ K + + A IIG K++ +V+LET +G R + PI DP+PRVC
Sbjct: 295 VLKALHKAGQ-KEAEIIGYATKEF-AEVVLETAVGTTRVVPQPISDPIPRVC 344
>gb|AAB64436.1| (AF006594) HupE [Anabaena PCC7120]
Length = 372
Score = 259 bits (655), Expect = 3e-68
Identities = 137/343 (39%), Positives = 209/343 (59%), Gaps = 11/343 (3%)
Query: 3 IRLEHGAGGELMEELIRDVILKNLTLNSAGGIGLEALDDGATIPIDGRHIVFTIDGHTVK 62
I L HG+GG+ M +LI D+ + N + +A + +T+ G + FT D + V
Sbjct: 32 ITLAHGSGGKAMRDLIDDIFVNNFDNPILSQLEDQATINLSTLLQQGERLAFTTDSYVVD 91
Query: 63 PLFFPGGDIGRLAVSGTVNDLAVMGAKPIALASSLIIGEGFDSQDLERI-----LKSMDE 117
PLFFPG DIG LA++GT+NDLAV GAKP+ S+I+ EG + L R+ + SM
Sbjct: 92 PLFFPGSDIGELAINGTINDLAVSGAKPLYFTCSVILEEGLPIETLRRVATSMKVPSMKV 151
Query: 118 TAKEVPVPIVTGDTKVVEENVG--IFVITAGIGIAEKPISDAGAKV--GDAVLVSGTIGD 173
A++ V IVTGDTKVV +F+ TAGIGI I + + GD+++++G +G+
Sbjct: 152 AAQKAGVQIVTGDTKVVPRGCADKLFINTAGIGIIPSGIDISAHNIQPGDSIIINGELGN 211
Query: 174 HGIALMSHREGISFETELKSDVAPTWDVVKAVADAIGWENIHAMKDPTRGGLSNALNEMA 233
HG A++ R ++ ET ++SD D+V + + +HAM+D TRGGL+ LNE A
Sbjct: 212 HGAAILIARGELALETNIESDCQALHDLVATILNVC--PQVHAMRDATRGGLATVLNEFA 269
Query: 234 RKANVGILIKESEIPIRPEVKAASEMLGISPYEVANEGKVVMIVEREYAEEALEAMRKTE 293
++VGI + E +P+R EVK E+LG+ P +ANEGK+V++V+ E A+ L AM+
Sbjct: 270 TSSHVGIRLYEESLPVREEVKGMCEILGLDPLHLANEGKLVVVVDSEQAQAVLSAMKSHP 329
Query: 294 KGRNAAIIGEVIKDYPGKVILETGIGGKRFLEPPIGDPVPRVC 336
KG++A I+GEV+ PG V L+T G +R ++ +G+ +PR+C
Sbjct: 330 KGQDACIVGEVMATPPGVVFLKTTFGTERIVDMLVGEQLPRIC 372
>sp|P26412|HYPE_RHOCA HYDROGENASE EXPRESSION/FORMATION PROTEIN HYPE
>gi|2126468|pir||S32953 hypE protein - Rhodobacter
capsulatus
Length = 340
Score = 239 bits (603), Expect = 4e-62
Identities = 130/339 (38%), Positives = 205/339 (60%), Gaps = 9/339 (2%)
Query: 2 KIRLEHGAGGELMEELIRDVILKNLTLNSAGGIGLEALDDGATIPIDGRHIVFTIDGHTV 61
++ L HG GG+ M +LI +V ++ G+ +A A + G + FT D + V
Sbjct: 7 RVTLAHGGGGKAMRDLIEEVFT---SVFQPPGMEDQARLTEAALAEPGARLAFTTDSYVV 63
Query: 62 KPLFFPGGDIGRLAVSGTVNDLAVMGAKPIALASSLIIGEGFDSQDLERILKSMDETAKE 121
P+ FPGGDIG++AV GTVNDLAV GA+P+ L+++ I+ EG + L RI+ +M A+
Sbjct: 64 TPVEFPGGDIGKIAVCGTVNDLAVGGARPLWLSAAFILEEGTEVALLRRIVATMAREAEA 123
Query: 122 VPVPIVTGDTKVVEENV--GIFVITAGIGIAEKPISDAGAKV--GDAVLVSGTIGDHGIA 177
V IVTGDTKVV G+FV T+G+G+ A +V GD +V+G +GDHG
Sbjct: 124 AGVRIVTGDTKVVGRGACDGVFVTTSGVGVIPPGREMAAGRVRPGDVAIVNGVLGDHGAT 183
Query: 178 LMSHREGISFETELKSDVAPTWDVVKAVADAIGWENIHAMKDPTRGGLSNALNEMARKAN 237
+++ R ++ ++++SD A ++ V A I A +D TRGGL++ALNE+A+ A
Sbjct: 184 ILAARGDLALTSDIESDCAALGHLMADVIAAA--PGIRAARDLTRGGLASALNEIAQTAG 241
Query: 238 VGILIKESEIPIRPEVKAASEMLGISPYEVANEGKVVMIVEREYAEEALEAMRKTEKGRN 297
G++I+E+ +P+RPEV E+LG+ P +ANEG++V+ V A AL AMR +G
Sbjct: 242 CGLVIEETALPLRPEVVGLCEILGLDPLYLANEGRLVVFVPEAEAAAALAAMRARPEGAG 301
Query: 298 AAIIGEVIKDYPGKVILETGIGGKRFLEPPIGDPVPRVC 336
A ++G + ++ G+V + T GG R ++ +G+ +PR+C
Sbjct: 302 ACVVGRAVAEHAGQVRMRTAFGGARIVDMLVGEQLPRIC 340
>pir||S77375 hydrogenase expression/formation protein hypE - Synechocystis sp.
(strain PCC 6803) >gi|1652557|dbj|BAA17478.1| (D90906)
hydrogenase expression/formation protein HypE
[Synechocystis sp.]
Length = 345
Score = 228 bits (574), Expect = 1e-58
Identities = 132/342 (38%), Positives = 203/342 (58%), Gaps = 17/342 (4%)
Query: 2 KIRLEHGAGGELMEELIRDVILKNLTLNSAGGIGLEALDDGATIPIDGRHIVFTIDGHTV 61
++ L HG GG+L ++L++ + L + G D A + + FT D + +
Sbjct: 14 QVLLAHGGGGKLSQQLLKQIFLPAFGASETGS------HDAAVFTANQSSLAFTTDSYVI 67
Query: 62 KPLFFPGGDIGRLAVSGTVNDLAVMGAKPIALASSLIIGEGFDSQDLERILKSMDETAKE 121
PLFFPGGDIG LAV GTVNDLA+ GA P ++ I+ EG + L R+ +S+ + A+
Sbjct: 68 NPLFFPGGDIGSLAVHGTVNDLAMAGATPRYISVGFILEEGLPMETLWRVAQSLGQAAQN 127
Query: 122 VPVPIVTGDTKVVE--ENVGIFVITAGIGIA--EKPISDAGAKVGDAVLVSGTIGDHGIA 177
V I+TGDTKVV+ + GIF+ T+GIG ++ I +VGD +++SG +G HG+A
Sbjct: 128 CGVEILTGDTKVVDRGKGDGIFINTSGIGSLDHQQTIHPNQVQVGDRLILSGDLGRHGMA 187
Query: 178 LMSHREGISFETELKSDVAPTWDVVKAVADAIGWENIHAMKDPTRGGLSNALNEMARKAN 237
+M+ R+G+ FET ++SD AP V+A+ A IH ++D TRGGL++A+NE+A+ +
Sbjct: 188 IMAVRQGLEFETTIESDSAPVHREVQALLSA--GIPIHCLRDLTRGGLASAVNEIAQTSG 245
Query: 238 VGILIKESEIPIRPEVKAASEMLGISPYEVANEGKVVMIVEREYAEEALEAMRKTEKGRN 297
V + ++E+ IP+ EV+AA E+LG P VANEG+ + IV E ++ +E ++
Sbjct: 246 VTMALRETLIPVEAEVQAACELLGFDPLYVANEGRFLAIVPPEAEQKTVEILQTFHP--Q 303
Query: 298 AAIIGEVI---KDYPGKVILETGIGGKRFLEPPIGDPVPRVC 336
A IG V G V LE+ IG R L+ G+ +PR+C
Sbjct: 304 ATAIGTVTGKSAQTLGLVSLESSIGAPRLLDMISGEQLPRIC 345
>gb|AAC26158.1| (AF035751) HypE [Synechococcus PCC7002]
Length = 348
Score = 227 bits (573), Expect = 1e-58
Identities = 139/346 (40%), Positives = 199/346 (57%), Gaps = 24/346 (6%)
Query: 3 IRLEHGAGGELMEELIRDVILKNLTLNSAGGIGLEALD-DGATIPIDGRHIVFTIDGHTV 61
+ L HG GG+LM++LI + A G D A +P+ + FT D + V
Sbjct: 15 VLLAHGGGGKLMQDLIDKMF--------ATAFGEPCTSHDAAALPVSTEKLAFTTDSYVV 66
Query: 62 KPLFFPGGDIGRLAVSGTVNDLAVMGAKPIALASSLIIGEGFDSQDLERILKSMDETAKE 121
+PLFFPGGDIG+LA+ GTVNDLA+ GA+P+ L+ I+ EG + L +++ SM + A+
Sbjct: 67 QPLFFPGGDIGKLAIYGTVNDLAMAGARPLYLSVGFILEEGLPLETLWQVVVSMQQAAQV 126
Query: 122 VPVPIVTGDTKVVE--ENVGIFVITAGIGIAEK--PISDAGAKVGDAVLVSGTIGDHGIA 177
V V IVTGDTKVVE + G+F+ T+GIGI E I GD +LVSG +G HGIA
Sbjct: 127 VGVQIVTGDTKVVERGKGDGLFINTSGIGIIESRLNIQPKAIAPGDTILVSGDLGRHGIA 186
Query: 178 LMSHREGISFETELKSDVAPTWDVVKAVADAIGWENIHAMKDPTRGGLSNALNEMARKAN 237
+M+ REG++FE+ ++SD AP + V+ + A G E IH ++D TRGGL LNE+A A
Sbjct: 187 IMAQREGLAFESPIESDCAPLVEPVQDLLKA-GIE-IHCLRDITRGGLGAVLNELAIAAG 244
Query: 238 VGILIKESEIPIRPEVKAASEMLGISPYEVANEGKVVMIVEREYAEEALEAMRKTEKGRN 297
+ ++IP+ V+ A E+ G P +ANEG+ V I+ A E L ++ N
Sbjct: 245 YQFKVHGNQIPVIEAVRGACEIFGFDPVHIANEGRFVAILPEARAAEGLALLQ--HYNAN 302
Query: 298 AAIIGEVIKDYPGK-------VILETGIGGKRFLEPPIGDPVPRVC 336
A IG V G+ V++E +G R LE G+ +PR+C
Sbjct: 303 ARQIGLVTTQNCGEQHLAIAPVVVENDLGVTRILERLSGEQLPRIC 348
>pir||S21906 hypE protein - Rhodobacter capsulatus >gi|46056|emb|CAA43329.1|
(X61007) HypE [Rhodobacter capsulatus]
Length = 322
Score = 226 bits (570), Expect = 3e-58
Identities = 119/298 (39%), Positives = 185/298 (61%), Gaps = 6/298 (2%)
Query: 43 ATIPIDGRHIVFTIDGHTVKPLFFPGGDIGRLAVSGTVNDLAVMGAKPIALASSLIIGEG 102
A + G + FT D + V P+ FPGGDIG++AV GTVNDLAV GA+P+ L+++ I+ EG
Sbjct: 27 AALAEPGARLAFTTDSYVVTPVEFPGGDIGKIAVCGTVNDLAVGGARPLWLSAAFILEEG 86
Query: 103 FDSQDLERILKSMDETAKEVPVPIVTGDTKVVEENV--GIFVITAGIGIAEKPISDAGAK 160
+ L RI+ +M A+ V IVTGDTKVV G+FV T+G+G+ A +
Sbjct: 87 TEVALLRRIVATMAREAEAAGVRIVTGDTKVVGRGACDGVFVTTSGVGVIPPGREMAAGR 146
Query: 161 V--GDAVLVSGTIGDHGIALMSHREGISFETELKSDVAPTWDVVKAVADAIGWENIHAMK 218
V GD +V+G +GDHG +++ R ++ ++++SD A ++ V A I A +
Sbjct: 147 VRPGDVAIVNGVLGDHGATILAARGDLALTSDIESDCAALGHLMADVIAAA--PGIRAAR 204
Query: 219 DPTRGGLSNALNEMARKANVGILIKESEIPIRPEVKAASEMLGISPYEVANEGKVVMIVE 278
D TRGGL++ALNE+A+ A G++I+E+ +P+RPEV E+LG+ P +ANEG++V+ V
Sbjct: 205 DLTRGGLASALNEIAQTAGCGLVIEETALPLRPEVVGLCEILGLDPLYLANEGRLVVFVP 264
Query: 279 REYAEEALEAMRKTEKGRNAAIIGEVIKDYPGKVILETGIGGKRFLEPPIGDPVPRVC 336
A AL AMR +G A ++G + ++ G+V + T GG R ++ +G+ +PR+C
Sbjct: 265 EAEAAAALAAMRARPEGAGACVVGRAVAEHAGQVRMRTAFGGARIVDMLVGEQLPRIC 322
>sp|P24193|HYPE_ECOLI HYDROGENASE ISOENZYMES FORMATION PROTEIN HYPE >gi|95947|pir||S15201
hydrogenase expression/formation protein hypE
[validated] - Escherichia coli >gi|41779|emb|CAA38416.1|
(X54543) hypE product [Escherichia coli]
>gi|1789085|gb|AAC75772.1| (AE000356) plays structural
role in maturation of all 3 hydrogenases [Escherichia
coli K12]
Length = 322
Score = 214 bits (539), Expect = 1e-54
Identities = 120/302 (39%), Positives = 184/302 (60%), Gaps = 13/302 (4%)
Query: 41 DGATIPIDGRHIVFTIDGHTVKPLFFPGGDIGRLAVSGTVNDLAVMGAKPIALASSLIIG 100
D A + +G + F+ D + + PLFFPGG+IG+LA+ GT ND+AV GA P L+ I+
Sbjct: 28 DLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILE 87
Query: 101 EGFDSQDLERILKSMDETAKEVPVPIVTGDTKVVEENV--GIFVITAGIGIAEKPISDAG 158
EG + L+ ++ SM ETA+ + IVTGDTKVV+ +F+ TAG+G I G
Sbjct: 88 EGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANI-HWG 146
Query: 159 AK---VGDAVLVSGTIGDHGIALMSHREGISFETELKSDVAPTWDVVKAVADAIGWENIH 215
A+ GD +LVSGT+GDHG +++ RE + + EL SD A +++ + D G +
Sbjct: 147 AQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPG---VK 203
Query: 216 AMKDPTRGGLSNALNEMARKANVGILIKESEIPIRPEVKAASEMLGISPYEVANEGKVVM 275
A++D TRGG++ ++E A GI + E+ +P++P V+ E+LG+ ANEGK+V+
Sbjct: 204 ALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVI 263
Query: 276 IVEREYAEEALEAMRKTEKGRNAAIIGEVIKDYPGKVILETGI-GGKRFLEPPIGDPVPR 334
VER AE+ L A+ G++AA+IGEV++ K + G+ G KR L+ P +P+PR
Sbjct: 264 AVERNAAEQVLAALHSHPLGKDAALIGEVVE---RKGVRLAGLYGVKRTLDLPHAEPLPR 320
Query: 335 VC 336
+C
Sbjct: 321 IC 322
>gb|AAA69240.1| (U29579) CG Site no. 33119; ORF_o322 [Escherichia coli]
Length = 322
Score = 211 bits (532), Expect = 8e-54
Identities = 119/302 (39%), Positives = 183/302 (60%), Gaps = 13/302 (4%)
Query: 41 DGATIPIDGRHIVFTIDGHTVKPLFFPGGDIGRLAVSGTVNDLAVMGAKPIALASSLIIG 100
D A + + + F+ D + + PLFFPGG+IG+LA+ GT ND+AV GA P L+ I+
Sbjct: 28 DLAQLVAEXDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILE 87
Query: 101 EGFDSQDLERILKSMDETAKEVPVPIVTGDTKVVEENV--GIFVITAGIGIAEKPISDAG 158
EG + L+ ++ SM ETA+ + IVTGDTKVV+ +F+ TAG+G I G
Sbjct: 88 EGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANI-HWG 146
Query: 159 AK---VGDAVLVSGTIGDHGIALMSHREGISFETELKSDVAPTWDVVKAVADAIGWENIH 215
A+ GD +LVSGT+GDHG +++ RE + + EL SD A +++ + D G +
Sbjct: 147 AQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPG---VK 203
Query: 216 AMKDPTRGGLSNALNEMARKANVGILIKESEIPIRPEVKAASEMLGISPYEVANEGKVVM 275
A++D TRGG++ ++E A GI + E+ +P++P V+ E+LG+ ANEGK+V+
Sbjct: 204 ALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVI 263
Query: 276 IVEREYAEEALEAMRKTEKGRNAAIIGEVIKDYPGKVILETGI-GGKRFLEPPIGDPVPR 334
VER AE+ L A+ G++AA+IGEV++ K + G+ G KR L+ P +P+PR
Sbjct: 264 AVERNAAEQVLAALHSHPLGKDAALIGEVVE---RKGVRLAGLYGVKRTLDLPHAEPLPR 320
Query: 335 VC 336
+C
Sbjct: 321 IC 322
>pir||A81411 hydrogenase isoenzymes formation protein Cj0626 [imported] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6968093|emb|CAB75262.1| (AL139075) hydrogenase
isoenzymes formation protein [Campylobacter jejuni]
Length = 324
Score = 195 bits (490), Expect = 7e-49
Identities = 128/340 (37%), Positives = 195/340 (56%), Gaps = 25/340 (7%)
Query: 3 IRLEHGAGGELMEELIRDV--ILKNLTLNSAGGIGLEALDDGATIPIDGRHIVFTIDGHT 60
I L HG GGE M EL+ + I N LN A +D A + ++ + D
Sbjct: 4 ISLAHGGGGEEMNELLTKLFKIFDNEILN--------ANNDAAILG----NLALSTDSFV 51
Query: 61 VKPLFFPGG-DIGRLAVSGTVNDLAVMGAKPIALASSLIIGEGFDSQDLERILKSMDETA 119
+ P+F +IG+L V G++ND+ ++GAKP L+ LI+ EGF+ + LERILKS+ E
Sbjct: 52 LSPIFLDEEVNIGKLCVCGSINDVLMVGAKPKYLSLGLILEEGFELEKLERILKSIKEEC 111
Query: 120 KEVPVPIVTGDTKVVEENVG--IFVITAGIGIAEKPISDAGAKVGDAVLVSGTIGDHGIA 177
++ V +V GDTKVV + I++ T +G K G ++L+SG IG HG +
Sbjct: 112 EKCGVMLVCGDTKVVPKGKADEIYINTTALGEIISKKESKNIKAGLSILLSGDIGRHGAS 171
Query: 178 LMSHREGISFETELKSDV-APTWDVVKAVADAIGWENIHAMKDPTRGGLSNALNEMARKA 236
++ R + E ++KSD A +V++ + I + AM+D TRGGLS LNE A+++
Sbjct: 172 VLIKRNEL--EADIKSDCKALNKEVLELLEKDI---KVVAMRDATRGGLSAVLNEWAKQS 226
Query: 237 NVGILIKESEIPIRPEVKAASEMLGISPYEVANEGKVVMIVEREYAEEALEAMRKTEKGR 296
+LI E +I ++ EV E+ G YE+ANEG ++ VE+E +ALE ++K
Sbjct: 227 GNDLLIFEEKIIVQDEVLGLCELFGYEAYELANEGTFILCVEKEDELKALEILKKYNV-- 284
Query: 297 NAAIIGEVIKDYPGKVILETGIGGKRFLEPPIGDPVPRVC 336
NA+IIGEV+++ +VIL+ G KRFLE P G+ +PR+C
Sbjct: 285 NASIIGEVLEEKKARVILQNAYGAKRFLESPKGELLPRIC 324
>pir||G64525 hydrogenase expression/formation protein - Helicobacter pylori
(strain 26695) >gi|2313121|gb|AAD07114.1| (AE000526)
hydrogenase expression/formation protein (hypE)
[Helicobacter pylori 26695]
Length = 332
Score = 191 bits (480), Expect = 1e-47
Identities = 109/300 (36%), Positives = 178/300 (59%), Gaps = 6/300 (2%)
Query: 40 DDGATIPIDGRHIVFTIDGHTVKPLFFPGGDIGRLAVSGTVNDLAVMGAKPIALASSLII 99
+D G + V T D + PL F GGDIG+L V G+ ND++V G +P+ L I+
Sbjct: 36 EDAPKFEASGEYCVST-DSFVITPLIFNGGDIGKLCVCGSANDVSVQGGEPLYLNMGFIL 94
Query: 100 GEGFDSQDLERILKSMDETAKEVPVPIVTGDTKVVEENV--GIFVITAGIGIAEKP-ISD 156
EG + L++IL+S+ + + + +++ DTKVV + +F+ T IG KP IS
Sbjct: 95 EEGLEISLLKQILQSIQKELFKANLKLLSLDTKVVPKGSVDKLFINTTCIGKIIKPGISS 154
Query: 157 AGAKVGDAVLVSGTIGDHGIALMSHREGISFETELKSDVAPTWDVVKAVADAIGWENIHA 216
+ G A+++S TI +HG +L + R I +T L+SD + ++K + + I A
Sbjct: 155 YHLQQGQAIILSDTIANHGASLFAMRNEIKLKTNLESDCQLLYPLLKPLF--LSDLKIDA 212
Query: 217 MKDPTRGGLSNALNEMARKANVGILIKESEIPIRPEVKAASEMLGISPYEVANEGKVVMI 276
++D TRGGL++ LNE A + V I+I+E +IP++ E K E+LG+ PY +ANEG V+
Sbjct: 213 LRDATRGGLASVLNEWANSSRVKIVIEEEKIPLKEETKGICEILGLEPYALANEGVFVLA 272
Query: 277 VEREYAEEALEAMRKTEKGRNAAIIGEVIKDYPGKVILETGIGGKRFLEPPIGDPVPRVC 336
+ ++ A +ALE ++ EK +NA +IG+V ++ V+L+ G +R LE P G+ +PR+C
Sbjct: 273 LNQKDAPKALEILKSNEKAKNACVIGKVFENPYPSVVLKNAWGFERILEVPEGELLPRIC 332
>pir||F71981 hydrogenase expression/formation protein - Helicobacter pylori
(strain J99) >gi|4154539|gb|AAD05617.1| (AE001443)
HYDROGENASE EXPRESSION/FORMATION PROTEIN [Helicobacter
pylori J99]
Length = 332
Score = 190 bits (477), Expect = 2e-47
Identities = 109/300 (36%), Positives = 177/300 (58%), Gaps = 6/300 (2%)
Query: 40 DDGATIPIDGRHIVFTIDGHTVKPLFFPGGDIGRLAVSGTVNDLAVMGAKPIALASSLII 99
+D G + V T D + PL F GGDIG+L V G+ ND++V G +P+ L I+
Sbjct: 36 EDAPKFEASGEYCVST-DSFVITPLIFNGGDIGKLCVCGSANDVSVQGGEPLYLNMGFIL 94
Query: 100 GEGFDSQDLERILKSMDETAKEVPVPIVTGDTKVVEENV--GIFVITAGIGIAEKP-ISD 156
EG + L++IL+S+ + + + +++ DTKVV + +F+ T IG KP IS
Sbjct: 95 EEGLEIPLLKQILQSIQKELFKANLKLLSLDTKVVPKGSVDKLFINTTCIGKIIKPGISS 154
Query: 157 AGAKVGDAVLVSGTIGDHGIALMSHREGISFETELKSDVAPTWDVVKAVADAIGWENIHA 216
+ G A+++S TI +HG +L + R I +T L+SD + ++K + + I A
Sbjct: 155 RHLQQGQAIILSDTIANHGASLFATRHEIKLKTNLQSDCQLLYPLLKPLF--LSDLKIDA 212
Query: 217 MKDPTRGGLSNALNEMARKANVGILIKESEIPIRPEVKAASEMLGISPYEVANEGKVVMI 276
++D TRGGL++ LNE A + V I+I+E +IP++ E K E+LG+ PY +ANEG V+
Sbjct: 213 LRDATRGGLASVLNEWANSSRVKIVIEEEKIPLKEETKGICEILGLEPYALANEGVFVLA 272
Query: 277 VEREYAEEALEAMRKTEKGRNAAIIGEVIKDYPGKVILETGIGGKRFLEPPIGDPVPRVC 336
+ ++ A +ALE ++ EK +NA +IG V ++ V+L+ G +R LE P G+ +PR+C
Sbjct: 273 LNQKDAPKALEILKSNEKAKNACVIGGVFENPYPSVVLKNAWGFERILEMPEGELLPRIC 332
>pir||F75178 hydrogenase expression/formation related protein PAB0403 -
Pyrococcus abyssi (strain Orsay)
>gi|5458019|emb|CAB49509.1| (AJ248284) hydrogenase
expression/formation related protein [Pyrococcus abyssi]
Length = 326
Score = 94.8 bits (232), Expect = 1e-18
Identities = 76/274 (27%), Positives = 138/274 (49%), Gaps = 17/274 (6%)
Query: 71 IGRLAVSGTVNDLAVMGAKPIALASSLIIGEGFDSQDLERILKSMDETAKEVPVPIVTGD 130
IG +V ND+A GAKP ++++ EG +D+ I+ + E ++ + + IV G
Sbjct: 60 IGFYSVHVNANDVATFGAKPKWFLVTILMPEGSSEEDIANIMAEIREVSEAMGIAIVGGH 119
Query: 131 TKVVEENVGIFVITAGIGIAEKP-ISDAGAKVGDAVLVSGTIGDHGIALMSHRE------ 183
T+V V+ +G ++ + K GDA++++ G G ++++H
Sbjct: 120 TEVTPGLKRPIVVGTMLGEVDRDNLVVPDPKPGDAIIMTKGAGIEGTSIIAHEREEELRG 179
Query: 184 --GISFETELKSDVAPTWDVVKAVADAIGWENIHAMKDPTRGGLSNALNEMARKANVGIL 241
G F K+ + V +A+ I E AM DPT GG++N ++EMA ++G
Sbjct: 180 VFGRDFVERAKAFIEEISIVREAM---IAREFATAMHDPTEGGIANGIHEMADINDLGFR 236
Query: 242 IKESEIPIRPEVKAASEMLGISPYEVANEGKVVMIVEREYAEEALEAMRKTEKGRNAAII 301
I +I IR E + + ++P + + G +++ V R++A+ +E R G +A+II
Sbjct: 237 IFAEKIIIRDETRKICDFYDLNPLALISSGALLISVPRDHAKFLVE--RLLSYGISASII 294
Query: 302 GEVIKDYPGKVILETGIGGKRFLEPPIGDPVPRV 335
GE + + +VI+E GI +R L+ P D + +V
Sbjct: 295 GEFLAE-KKRVIIENGI--ERPLKRPESDELWKV 325
>pir||E71035 probable hydrogenase expression/formation protein - Pyrococcus
horikoshii >gi|3258002|dbj|BAA30685.1| (AP000006) 326aa
long hypothetical hydrogenase expression/formation
protein [Pyrococcus horikoshii]
Length = 326
Score = 92.1 bits (225), Expect = 8e-18
Identities = 76/275 (27%), Positives = 135/275 (48%), Gaps = 19/275 (6%)
Query: 71 IGRLAVSGTVNDLAVMGAKPIALASSLIIGEGFDSQDLERILKSMDETAKEVPVPIVTGD 130
IG AV+ ND+A GA+P ++++ EG + D+ I+ + E A+ + + IV G
Sbjct: 60 IGFYAVNINANDVATFGARPKWFLVTILLPEGSEFNDVITIMDEVREVAEGMGISIVGGH 119
Query: 131 TKVVEENVGIFVITAGIGIAEKP-ISDAGAKVGDAVLVSGTIGDHGIALMSHREGISFET 189
T+V V+ +G EK + + GDA++++ G G ++++H E
Sbjct: 120 TEVTPGLKKPIVVGTMLGEVEKENLVVPNPRPGDAIILTKGAGIEGTSIIAHER----EE 175
Query: 190 ELKSDVAPTW--------DVVKAVADAI-GWENIHAMKDPTRGGLSNALNEMARKANVGI 240
ELK + + + V +A+ E AM DPT GG++N L+EMA +G
Sbjct: 176 ELKGVFGSNFVERAKAFINEISIVREALLSREFATAMHDPTEGGIANGLHEMADINGLGF 235
Query: 241 LIKESEIPIRPEVKAASEMLGISPYEVANEGKVVMIVEREYAEEALEAMRKTEKGRNAAI 300
I +++ IR E + + P + + G +++ R++A+ +E R G A+I
Sbjct: 236 RIFANKVIIREETRKICHFYDLDPLALISSGALLISTPRDHAKFLIE--RLLSHGIQASI 293
Query: 301 IGEVIKDYPGKVILETGIGGKRFLEPPIGDPVPRV 335
IGE + + +VI+E G +R L+ P D + +V
Sbjct: 294 IGEFLAE-KKRVIIEN--GAERPLKRPESDELWKV 325
>gb|AAK42820.1| Hydrogenase expression/formation factor related protein [Sulfolobus
solfataricus]
Length = 341
Score = 82.7 bits (201), Expect = 5e-15
Identities = 82/306 (26%), Positives = 137/306 (43%), Gaps = 23/306 (7%)
Query: 39 LDDGATIPIDGRHIVFTIDGHTVKPLFFPGGDIGRLAVSGTVNDLAVMGAKPIALASSLI 98
+D GA DGR +V D + P F AV +D+ G P L
Sbjct: 34 VDTGAIDLQDGRVLVVKTDPVFIVPQF-GFKKAAWFAVHILASDVMTSGIPPEYAVIDLN 92
Query: 99 IGEGFDSQDLERILKSMDETAKEVPVPIVTGDTKVVEEN----VGIFVITAGIGIAEKPI 154
+ ++ E + + E KE+ V +V G T V E VG F + GIG E+
Sbjct: 93 LPPRIKDEEFEEMWIGIHEALKEIGVMVVGGHTGVYEGTDYPMVGGFTMF-GIGEKERLG 151
Query: 155 SDAGAKVGDAVLVSGTIGDHGIALMSHREGISFETELKSDVAPT-----WDVV----KAV 205
+ KVGD+V+++ L+++ F+ L +++ W + +
Sbjct: 152 MPSKVKVGDSVIMTKGPAIEATGLLTNLYPEYFKQRLSNEIFNEAYNMYWKMSCWKDGLI 211
Query: 206 ADAIGWENIHAMKDPTRGGLSNALNEMARKANVGILIKESEIPIRPEVKAASEMLGISPY 265
A IG IH M D T GG+ AL E+AR ++ G+ I E I V+ ++++ I P+
Sbjct: 212 ASRIG---IHMMHDATEGGVFGALTEVARASSKGMRIYEERFFINRAVREVTKLVNIDPW 268
Query: 266 EVANEGKVVMIVEREYAEEALEAMRKTEKGRNAAIIGEVIKDYPGKVILETGIGGKRFLE 325
+EG ++++ ++ EE + +G A IIGE++ D G+V + G + +E
Sbjct: 269 ISISEGTMIIVTDK--GEEVRNTL--IREGIEAEIIGEIV-DQSGEVTMVKKDGSRVKIE 323
Query: 326 PPIGDP 331
P+ DP
Sbjct: 324 HPLEDP 329
>sp|O27427|PURL_METTH PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE II (FGAM SYNTHASE II)
>gi|7428514|pir||G69049
phosphoribosylformylglycinamidine synthase (EC 6.3.5.3)
component II - Methanobacterium thermoautotrophicum
(strain Delta H) >gi|2622483|gb|AAB85851.1| (AE000900)
phosphoribosylformylglycinamidine synthase II
[Methanobacterium thermoautotrophicum]
Length = 714
Score = 80.8 bits (196), Expect = 2e-14
Identities = 86/322 (26%), Positives = 139/322 (42%), Gaps = 54/322 (16%)
Query: 40 DDGATIPI-DGRHIVFTIDGHTVKPLFFPGGDIGRLAVSGTVNDLAVMGAKPIALASSLI 98
DD + I D +V I+ H P G G + G + D+ MGA P+AL SL
Sbjct: 60 DDAGVVEITDELALVIGIESHNHPSAIEPYGGAGT-GIGGILRDIISMGAMPVALLDSLR 118
Query: 99 IGEGFDSQD---LERILKSMDETAKEVPVPIVTGDTKVVEE---NVGIFVITAGI----- 147
G D + E +++ + + V VP V G+ + E N + V+ AG+
Sbjct: 119 FGYLEDQKSRYLFEHVVRGISDYGNRVGVPTVAGEVEFDENFQLNPLVNVMCAGLVPKND 178
Query: 148 ---GIAEKPISDAGAKVGDAVLV----SGTIGDHGIALMSHREGISFETELKSDVAPTWD 200
GIA +P GD L+ +G G HG+ S S E E + V
Sbjct: 179 IKRGIAPRP--------GDVFLLMGGRTGRDGIHGVTFASEELTSSSELEDRPAVQVGDP 230
Query: 201 VVKAVADAIGWE-----NIHAMKDPTRGGLSNALNEMARKANVGILIKESEIPIRPEVKA 255
K + +E + +KD GGL+ ++E+ K + G + IP+R E
Sbjct: 231 FTKKMVMEASFEIMDEIEVSGVKDLGGGGLTCCISELVAKCDNGARVSLEAIPLREE--- 287
Query: 256 ASEMLGISPYEV---ANEGKVVMIVEREYAEEALEAMRKTEKGRNAAIIGEV------IK 306
G++PYE+ ++ +++ ++ + E A+E RK E AA+IGEV I
Sbjct: 288 -----GMTPYEIMLSESQERMIFVMAPDDVEAAMEICRKYE--LPAAVIGEVTDTGRMIV 340
Query: 307 DYPGKVILETGIGGKRFLEPPI 328
+ G+VI + + K +PP+
Sbjct: 341 ESEGEVIAD--LPAKLLADPPV 360
>sp|O59497|THIL_PYRHO PROBABLE THIAMINE-MONOPHOSPHATE KINASE (THIAMINE-PHOSPHATE KINASE)
>gi|7446700|pir||B71195 hypothetical protein PH1833 -
Pyrococcus horikoshii >gi|3258270|dbj|BAA30953.1|
(AP000007) 309aa long hypothetical protein [Pyrococcus
horikoshii]
Length = 309
Score = 80.4 bits (195), Expect = 3e-14
Identities = 68/219 (31%), Positives = 101/219 (46%), Gaps = 11/219 (5%)
Query: 40 DDGATIPIDGRHIVFTID---GHTVKPLFFPGGDIGRLAVSGTVNDLAVMGAKPIALASS 96
DD + + ++ T D T P F + G+ V+ V+D+A MG P+A S
Sbjct: 24 DDAGFVRFNDSWLLVTSDMLVWRTDVPDFMTPEEAGKKVVTMNVSDIAAMGGLPLAFFFS 83
Query: 97 LIIGEGFDSQDLERILKSMDETAKEVPVPIVTGDTKVVEENVGIFVITAGIGIAEKPISD 156
L + E D + L I K +++ AKE V IV+GDT E I + IG + +
Sbjct: 84 LGVPENTDEKTLRGIAKGINKGAKEYGVKIVSGDTNEARE---IIIDGGAIGRGSRLLLR 140
Query: 157 AGAKVGDAVLVSGTIGDHGIALMSHREGISFETELKSDVAPTWDVVKA-VADAIGWENIH 215
+ AK GD V V+G +G AL+ +G E+ + KA + I N
Sbjct: 141 SNAKPGDLVCVTGELGRPLTALLLWLKG----EEIPPKILEKAKNPKAREREGIELSNYA 196
Query: 216 AMKDPTRGGLSNALNEMARKANVGILIKESEIPIRPEVK 254
GLS L E+AR +NV I+I E +IP+ EV+
Sbjct: 197 NSAIDISDGLSKELWEIARSSNVRIVIDEDKIPVNEEVR 235
>pir||H75153 thiamin monophosphate kinase (thil) PAB2358 - Pyrococcus abyssi
(strain Orsay) >gi|5457821|emb|CAB49311.1| (AJ248284)
thiamine monophosphate kinase (thiL) [Pyrococcus abyssi]
Length = 310
Score = 80.4 bits (195), Expect = 3e-14
Identities = 69/252 (27%), Positives = 114/252 (44%), Gaps = 17/252 (6%)
Query: 40 DDGATIPIDGRHIVFTID---GHTVKPLFFPGGDIGRLAVSGTVNDLAVMGAKPIALASS 96
DD I ++ ++ T D T P F D GR V+ V+D+A MG +P+A S
Sbjct: 25 DDAGFIKLNNSWLLVTSDMLVWKTDVPDFMTPEDAGRKVVTMNVSDIAAMGGRPMAFFFS 84
Query: 97 LIIGEGFDSQDLERILKSMDETAKEVPVPIVTGDTKVVEENVGIFVITAGIGIAEKPISD 156
L + L I + ++E +K + IV+GDT ++ I + +GI ++ +
Sbjct: 85 LAVPGDVSEDILRGIARGINEGSKVYKLKIVSGDTNEADD---IIIDGGSLGIGKRLLLR 141
Query: 157 AGAKVGDAVLVSGTIGDHGIALMSHREGISFETELKSDVAPTWDVVKAVADAIGWENIHA 216
+ AK GD V V+G +G AL+ G E++ + V + + ++
Sbjct: 142 SNAKPGDLVCVTGDLGRPLTALLLWMRGEKIPREIEEKAR---NPRARVEEGVKLSSLAN 198
Query: 217 MKDPTRGGLSNALNEMARKANVGILIKESEIPIRPEVKAASEMLGISPYEVA----NEGK 272
GLS L E+A +NV I+I+E +PI VK + P +VA E +
Sbjct: 199 SAIDISDGLSKELWEIANASNVRIIIEEERLPISDSVKE----IVSDPVKVALASGEEFE 254
Query: 273 VVMIVEREYAEE 284
++ + RE EE
Sbjct: 255 LLFTIPREKVEE 266
>gb|AAG18782.1| (AE004983) hydrogenase expression/formation; Hef [Halobacterium sp.
NRC-1]
Length = 339
Score = 78.0 bits (189), Expect = 1e-13
Identities = 68/241 (28%), Positives = 108/241 (44%), Gaps = 26/241 (10%)
Query: 80 VNDLAVMGAKPIALASSLIIGEGFDSQDLERILKSMDETAKEVPVPIVTGDTKVVEENVG 139
V+D+A+ G P LA L + ++ + I + D A+ + V + TG T E G
Sbjct: 73 VSDVALSGLSPAHLAVDLNLPPDTATETFDAIWEVFDREARALGVSLTTGHTGTYE---G 129
Query: 140 IFVITAG------IGIAEKPISDAGAKVGDAVLVSG-----TIGDHGIALMSHREGISFE 188
T G +G AE ++ GA+ GD V+V+ T G G+ L R IS
Sbjct: 130 CSFPTVGGATALAVGAAEDVVTPTGAQPGDRVVVTKGPAVETTGMLGV-LFGDRLPISAA 188
Query: 189 TELKS-----DVAPTWDVVKAVADAIGWENIHAMKDPTRGGLSNALNEMARKANVGILIK 243
+ D P D A + AM D T GL+N L+E+A + VG+ +
Sbjct: 189 AAAAARDRFADATPVRDAATMAAAG----EVTAMHDATERGLANGLHELAAASGVGLSVA 244
Query: 244 ESEIPIRPEVKAASEMLGISPYEVANEGKVVMIVEREYAEEALEAMRKTEKGRNAAIIGE 303
+P+ P V+A E G+ + ++EG V+ V+ + L A+ ++G AA +G
Sbjct: 245 RDAVPVLPGVRAVCEQFGMDAWAASSEGTVIAAVDPGSVDAVLGAL--GDEGIPAADVGV 302
Query: 304 V 304
V
Sbjct: 303 V 303
>pir||A75026 phosphoribosylformylglycinamidine synthase II (purl) PAB1201 -
Pyrococcus abyssi (strain Orsay)
>gi|5459161|emb|CAB50647.1| (AJ248288)
phosphoribosylformylglycinamidine synthase II (purL)
[Pyrococcus abyssi]
Length = 705
Score = 74.9 bits (181), Expect = 1e-12
Identities = 79/287 (27%), Positives = 130/287 (44%), Gaps = 30/287 (10%)
Query: 40 DDGATIPID-GRHIVFTIDGHTVKPLFFPGGDIGRLAVSGTVNDLAVMGAKPIALASSLI 98
+D + D IV I+ H P G + G V D+ MGA+PIAL +
Sbjct: 58 EDAGVVKFDESTWIVIGIESHNHPSAVEPYGGAAT-GIGGIVRDILCMGARPIALLDPIR 116
Query: 99 IGEGFDSQD---LERILKSMDETAKEVPVPIVTGDTKVVE--ENVGIF-VITAGIGIAEK 152
G ++ E ++K + + + VP V G+T+ E +N + V+ GI E
Sbjct: 117 FGPLEKEKNRYLFEYVVKGIADYGNRIGVPTVGGETEFDESLDNYTLVNVVCVGIMKPEH 176
Query: 153 PISDAGAKVG-DAVLV---SGTIGDHGIALMSHREGISFETELKSDVA---PTWD--VVK 203
+ K G VLV +G G HG+ S + E E +S V P + +++
Sbjct: 177 LVHSYVTKPGLKLVLVGNRTGRDGIHGVTFASEELSENAEEEDRSAVQIPDPFTEKLLIE 236
Query: 204 AVADAIGWENIHAMKDPTRGGLSNALNEMARKANVGILIKESEIPIRPEVKAASEMLGIS 263
A +A+ + A+KD GGL+ A +EMA K +G +I +P+R G++
Sbjct: 237 ATLEAVYTGKVKALKDLGGGGLTCAASEMAGKKGLGAVIYADRVPLREP--------GMT 288
Query: 264 PYEV---ANEGKVVMIVEREYAEEALEAMRKTEKGRNAAIIGEVIKD 307
P EV ++ +++ VE E EE + K E A++GE+I++
Sbjct: 289 PLEVMISESQERMLFAVEPEDVEELAKIFEKYE--LEWAVVGEIIEE 333
>pir||G64476 hypothetical protein MJ1416 - Methanococcus jannaschii
>gi|1500295|gb|AAB99426.1| (U67582) conserved
hypothetical protein [Methanococcus jannaschii]
Length = 452
Score = 74.1 bits (179), Expect = 2e-12
Identities = 74/279 (26%), Positives = 130/279 (46%), Gaps = 29/279 (10%)
Query: 34 IGLEALDDGATIPIDGRHIVFTIDGHTVKPLFFP---GGDIGRLAVSGTVNDLAVMGAKP 90
+ E DD + D ++IV IDG + FP G + R A+ D+ VMGA+
Sbjct: 111 VSAEEQDDAGIVRADAKYIVAAIDGTHSRLSDFPFLGGFHVTRAAL----RDIYVMGAEA 166
Query: 91 IALASSLIIGEGFDSQDLERILKSMDETAKEVPVPIVTGDTKVVEEN--VGIFVITA--G 146
+AL S + + + D + + ++ V VP++ G T V + +G +++A
Sbjct: 167 VALISDVHLADDGDVGKIFDFTAGICAVSEAVNVPLIGGSTLRVGGDMVIGDRLVSAVGA 226
Query: 147 IGIAEK--PISDAGAKVGDAVLVSGTIGDHGIALMSHREG---ISFETELKSDVAPTWDV 201
IG+ ++ P + A+VGD +L++ G I + G + +ET D
Sbjct: 227 IGVIKEGEPTARRNAEVGDVILMTEGSGGGTITTTALYYGWFDVIYETL-------NVDF 279
Query: 202 VKAVADAIGW---ENIHAMKDPTRGGLSNALNEMARKANVGILIKESEI--PIRPEVKAA 256
+KA + I + IHAM D T GGL E+++ A V ++ + ++ I P+V
Sbjct: 280 IKACQNLIRSGLIKKIHAMTDVTNGGLRGDAYEISKTAKVSLIFDKEKVYKTINPKVLEM 339
Query: 257 SEMLGISPYEVANEGKVVMIVEREYAEEALEAMRKTEKG 295
E+L I P V+ + +++I EYA++ + E G
Sbjct: 340 LEVLNIDPLGVSTD-SLMIICPEEYADDIKKVTGAIEVG 377
>pir||F72508 probable hydrogenase expression/formation protein APE2044 -
Aeropyrum pernix (strain K1) >gi|5105742|dbj|BAA81054.1|
(AP000063) 308aa long hypothetical hydrogenase
expression/formation protein [Aeropyrum pernix]
Length = 308
Score = 73.7 bits (178), Expect = 3e-12
Identities = 79/309 (25%), Positives = 127/309 (40%), Gaps = 32/309 (10%)
Query: 40 DDGATIPIDGRHIVFTIDGHTVKPLFFPGGDIGRLAVSGTVNDLAVMGAKPIALASSLII 99
+D A + + +V +D P+ G G LAV ND+AV GA+P ++++
Sbjct: 3 EDAAIVSLGPIDLVMHLD-----PITEAGALAGWLAVHVAANDIAVTGARPRWEMLAVLM 57
Query: 100 GEGFDSQDLERILKSMDETAKEVPVPIVTGDTKVVEENVGIFVITAGIGIA----EKPIS 155
G L +L A+E+ V IV G T+ ++ A GI P S
Sbjct: 58 PPGSSEDSLASLLGDAVRAAEEIGVEIVGGHTEAAPGVPRPIIVAAAAGITCGGCTTPTS 117
Query: 156 DAGAKVGDAVLVSGTIGDHGIALMSH------------REGISFETELKSDVAPTWDVVK 203
A+ GD VL G A+++ + I+ L S V+ + ++
Sbjct: 118 --AARPGDLVLQVKPAAIEGTAIIATDFADMLRSRGVGEDAIAGARMLASRVSIVEEAIE 175
Query: 204 AVADAIGWENIHAMKDPTRGGLSNALNEMARKANVGILIKESEIPIRPEVKAASEMLGIS 263
+ + AM DPT GG+ L EMA + I ++E +I + + + LGI
Sbjct: 176 LAEAGV----VRAMHDPTEGGVLGGLVEMALASRTVIEVEEDKIIVGEATRIVASALGID 231
Query: 264 PYEVANEGKVVMIVEREYAEEALEAMRKTEKGRNAAIIGEVIKDYPGKVILETGIGG--K 321
P + + G ++ V + A EA + E G + IG V G+ L G K
Sbjct: 232 PLRLISSGTLLATVPPDKAGEARYVLE--ELGVEYSFIGRVAA-RSGEPALRLSSRGRVK 288
Query: 322 RFLEPPIGD 330
F EPP+ +
Sbjct: 289 TFREPPMDE 297
>gb|AAK40418.1| Hydrogenase expression/formation protein (hypE) [Sulfolobus
solfataricus]
Length = 343
Score = 71.8 bits (173), Expect = 1e-11
Identities = 72/298 (24%), Positives = 132/298 (44%), Gaps = 34/298 (11%)
Query: 40 DDGATIPIDGRHIVFTIDGHTVKPLFFPGGDIGRLAVSGTVNDLAVMGAKPIALASSLII 99
+D A + ++++ D P+ D G L+++ ND+ + GA+ + S +++
Sbjct: 53 EDAAVLEAKDKYLIVHSD-----PITEAKSDSGFLSIAVACNDINMKGAQCRWVNSIILL 107
Query: 100 GEGFDSQDLERILKSMDETAKEVPVPIVTGDTKVVEENVGIFVITAGIGIAEKPISDAGA 159
D L + ++ E + +V G T+V ++ +IT IG++ K +S
Sbjct: 108 S---DISHLNATISAISEACNLIGCKVVGGHTEVSDKVKQDIIITTAIGVSNKFLSYKNV 164
Query: 160 KVGDAVLVSGTIGDHGIALMS------------HREGISFETELKSDVAPTWDVVKAVAD 207
K G V++ G+ G G +++ RE I E K D+ VV+ A
Sbjct: 165 KEGMKVVLVGSPGIEGTWILAKDYDQLLLEKGISREIIEKAKEFKKDI-----VVQPKAL 219
Query: 208 AIGWENIHAMKDPTRGGLSNALNEMARKANVGILIKESEIPIRPEVKAASEMLGISPYEV 267
+I + + AM D T GG+ A+ E+A+ + + I +I +R E K ++ L I P +
Sbjct: 220 SI-LDYVVAMHDATEGGIMQAMLEVAKASGYTVSINLDKIVLRRETKIITKALNIDPLRL 278
Query: 268 ANEGKVVMIVEREYAEEALEAMRKTEKGRNAAIIGEVIKDYPGKVILETGIGGKRFLE 325
+ G + + E+ LE + + A IIGE+ + P I G + F E
Sbjct: 279 ISSGSFIAV--SNTPEKILERISE------AYIIGEIKRGDPVLEIKGVGTFNQDFEE 328
>pir||S75435 hypothetical protein c05018 - Sulfolobus solfataricus
>gi|1707841|emb|CAA69519.1| (Y08257) orf c05018
[Sulfolobus solfataricus]
Length = 343
Score = 71.8 bits (173), Expect = 1e-11
Identities = 72/298 (24%), Positives = 132/298 (44%), Gaps = 34/298 (11%)
Query: 40 DDGATIPIDGRHIVFTIDGHTVKPLFFPGGDIGRLAVSGTVNDLAVMGAKPIALASSLII 99
+D A + ++++ D P+ D G L+++ ND+ + GA+ + S +++
Sbjct: 53 EDAAVLEAKDKYLIVHSD-----PITEAKSDSGFLSIAVACNDINMKGAQCRWVNSIILL 107
Query: 100 GEGFDSQDLERILKSMDETAKEVPVPIVTGDTKVVEENVGIFVITAGIGIAEKPISDAGA 159
D L + ++ E + +V G T+V ++ +IT IG++ K +S
Sbjct: 108 S---DISHLNATISAISEACNLIGCKVVGGHTEVSDKVKQDIIITTAIGVSNKFLSYKNV 164
Query: 160 KVGDAVLVSGTIGDHGIALMS------------HREGISFETELKSDVAPTWDVVKAVAD 207
K G V++ G+ G G +++ RE I E K D+ VV+ A
Sbjct: 165 KEGMKVVLVGSPGIEGTWILAKDYDQLLLEKGISREIIEKAKEFKKDI-----VVQPKAL 219
Query: 208 AIGWENIHAMKDPTRGGLSNALNEMARKANVGILIKESEIPIRPEVKAASEMLGISPYEV 267
+I + + AM D T GG+ A+ E+A+ + + I +I +R E K ++ L I P +
Sbjct: 220 SI-LDYVVAMHDATEGGIMQAMLEVAKASGYTVSINLDKIVLRRETKIITKALNIDPLRL 278
Query: 268 ANEGKVVMIVEREYAEEALEAMRKTEKGRNAAIIGEVIKDYPGKVILETGIGGKRFLE 325
+ G + + E+ LE + + A IIGE+ + P I G + F E
Sbjct: 279 ISSGSFIAV--SNTPEKILERISE------AYIIGEIKRGDPVLEIKGVGTFNQDFEE 328
>emb|CAC12402.1| (AL445067) hydrogenase expression/formation protein (Anabaena hupE)
related protein [Thermoplasma acidophilum]
Length = 334
Score = 71.8 bits (173), Expect = 1e-11
Identities = 73/298 (24%), Positives = 130/298 (43%), Gaps = 21/298 (7%)
Query: 48 DGRHIVFTIDGHTVKPLFFPGGDIGRLAVSGTVNDLAVMGAKPIALASSLIIGEGFDSQD 107
DGR + T D P+F D A +DL GA P + L + ++
Sbjct: 30 DGRVMSVTTDPFYFDPVF-GYEDSAWFAYHILASDLLTSGANPDYMTVDLNLPLSMTDEE 88
Query: 108 LERILKSMDETAKEVPVPIVTGDTKVVEEN----VGIFVITAGIGIAEKPISDAGAKVGD 163
+ R+ + E A I+TG T +G IG ++ ++ A A+ GD
Sbjct: 89 ISRMWNAFTEEAARFGTSIITGHTARYAGTSFPMIGGITAMGFIG-EDEYVTSAMARPGD 147
Query: 164 AVLVSGTIGDHGIALMSHREGISFETELKSDV----APTWDVVKAVADAIGWEN------ 213
V+++ T AL++ + + +L ++ + + V +++ +
Sbjct: 148 KVVLTKTPAIEAAALLTRLFPGTIKAKLGDELFSYGVDLFRKLTTVHESLVCKRFGLRTR 207
Query: 214 IHAMKDPTRGGLSNALNEMARKANVGILIKESEIPIRPEVKAASEMLGISPYEVANEGKV 273
+ AM D T GGL AL E+A + GI I E I + VK + I P +EG +
Sbjct: 208 VTAMHDVTEGGLLGALFEIADSSGNGIRIHEDSIKVDDYVKRVCSIFSIDPLMAISEGAL 267
Query: 274 VMIVEREYAEEALEAMRKTEKGRNAAIIGEVIKDYPGKVILETGIGGKRFLEPPIGDP 331
++ V+ ++AE+ + +++ G +A +IGE+ D ++I+ KR + PP DP
Sbjct: 268 LITVKPDHAEDLVSSLK--ANGIDANVIGEMTADPSERIIVGR---EKRTIGPPQKDP 320
>sp|Q58660|PURL_METJA PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE II (FGAM SYNTHASE II)
>gi|2129201|pir||G64457
phosphoribosylformylglycinamidine synthase (EC 6.3.5.3)
component II - Methanococcus jannaschii
>gi|1591899|gb|AAB99270.1| (U67567)
phosphoribosylformylglycinamidine synthase II (purL)
[Methanococcus jannaschii]
Length = 733
Score = 70.6 bits (170), Expect = 2e-11
Identities = 77/313 (24%), Positives = 139/313 (43%), Gaps = 42/313 (13%)
Query: 29 NSAGGIGLEALDDGATIPIDGRH-IVFTIDGHTVKPLFFPGGDIGRLAVSGTVNDLAVMG 87
N GIG DD A I + + ++ H P + + V G V D+ MG
Sbjct: 56 NIVVGIG----DDAAVIRLKNDICLAIAMESHN-HPSYIDPYNGAATGVGGIVRDVLSMG 110
Query: 88 AKPIALASSLIIGEGFDSQD------LERILKSMDETAKEVPVPIVTGDTKV---VEENV 138
AKPIAL L G+ F + +E ++K + + + VP V G+ + + N
Sbjct: 111 AKPIALLDPLRFGDIFGKEGDKVRWLIEGVVKGIGDYGNRIGVPTVGGECEFDSSFDYNN 170
Query: 139 GIFVITAGIGIAEKPISDAGAKVGDAVLVSGTIGDHGIALMSH-REGISFETELKSDVAP 197
+ V+ G+ + I+ + G ++++ G+ G GI S + ++ E+E +
Sbjct: 171 LVNVVCVGLVKENEIITGKAKEPGLSLILIGSTGRDGIGGASFASKDLTEESEEERPSVQ 230
Query: 198 TWD------VVKAVADAIGWENIHAMKDPTRGGLSNALNEMARKANVGILIKESEIPIRP 251
D ++ AV +A+ + AMKD GLS A +EM VG + + +R
Sbjct: 231 VGDAFSEKCLIDAVLEAVKTGKVKAMKDLGAAGLSGASSEMCYGGGVGCELYLENVVLRE 290
Query: 252 EVKAASEMLGISPYEV---ANEGKVVMIVEREYAEEALEAMRKTEKGRNAAIIGE----- 303
++PYE+ ++ ++++ VE EE +E +K E A++IG+
Sbjct: 291 P---------LTPYEIMVSESQERMLLAVEPGSEEEIIEIFKKYE--LPASVIGKTIPEK 339
Query: 304 -VIKDYPGKVILE 315
+I Y G+V+++
Sbjct: 340 RIIAKYKGEVVVD 352
>pir||A71211 probable phosphoribosylformylglycinamidine synthase II - Pyrococcus
horikoshii >gi|3258397|dbj|BAA31080.1| (AP000007) 705aa
long hypothetical phosphoribosylformylglycinamidine
synthase II [Pyrococcus horikoshii]
Length = 705
Score = 68.7 bits (165), Expect = 9e-11
Identities = 73/287 (25%), Positives = 123/287 (42%), Gaps = 30/287 (10%)
Query: 40 DDGATIPIDGRH-IVFTIDGHTVKPLFFPGGDIGRLAVSGTVNDLAVMGAKPIALASSLI 98
+D I D + IV I+ H P G V G V D+ MGA+PIAL +
Sbjct: 58 EDAGIIKFDDKTWIVIGIESHNHPSAVEPYGGAAT-GVGGIVRDILCMGARPIALLDPIR 116
Query: 99 IGEGFDSQD---LERILKSMDETAKEVPVPIVTGDTKVVEE-------NVGIFVITAGIG 148
G ++ E ++K + + + VP V G+T+ E NV I
Sbjct: 117 FGPLEKEKNRYLFEYVVKGISDYGNRIGVPTVGGETEFDESLDNYTLVNVACVGIMKPEH 176
Query: 149 IAEKPISDAGAKVGDAVLVSGTIGDHGIALMSHREGISFETELKSDVA---PTWD--VVK 203
+ +++ G K+ +G G HG+ S + E E +S V P + +++
Sbjct: 177 LVHSYVTEPGLKLIIVGNRTGRDGIHGVTFASEELSENAEEEDRSAVQIPDPFTEKLLIE 236
Query: 204 AVADAIGWENIHAMKDPTRGGLSNALNEMARKANVGILIKESEIPIRPEVKAASEMLGIS 263
A +A+ + A+KD GGL+ A +EM K G +I ++ +R G++
Sbjct: 237 ATLEAVYTGKVRALKDLGGGGLTCAASEMVGKRGFGAIIYADKVLLREP--------GMT 288
Query: 264 PYEV---ANEGKVVMIVEREYAEEALEAMRKTEKGRNAAIIGEVIKD 307
P EV ++ +++ V E EE K E +++GEVI++
Sbjct: 289 PLEVMISESQERMLFAVRPEDVEELARIFEKYE--LEWSVVGEVIEE 333
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.316 0.138 0.389
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 124013062
Number of Sequences: 2977
Number of extensions: 5245406
Number of successful extensions: 10311
Number of sequences better than 1.0e-10: 39
Number of HSP's better than 0.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 10191
Number of HSP's gapped (non-prelim): 43
length of query: 336
length of database: 189,106,746
effective HSP length: 57
effective length of query: 279
effective length of database: 154,992,987
effective search space: 43243043373
effective search space used: 43243043373
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 42 (22.0 bits)
S2: 165 (68.7 bits)