BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB0874 (PAB0874) DE:TRANSPORTER (MAJOR FACILITATOR FAMILY)
related
         (392 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||E75042 transporter (major facilitator family) related PAB08...   763  0.0
pir||G71118 hypothetical protein PH0718 - Pyrococcus horikoshii ...   667  0.0
pir||D64464 hypothetical protein MJ1317 - Methanococcus jannasch...   269  5e-71
gb|AAD38864.1| (L09121) hypothetical protein [Thermus thermophilus]   221  9e-57
pir||T45544 hypothetical protein 3 [imported] - Klebsiella pneum...   189  4e-47
pir||A72413 conserved hypothetical protein - Thermotoga maritima...   150  3e-35
pir||G69201 conserved hypothetical protein MTH761 - Methanobacte...   130  3e-29
gi|11499136 conserved hypothetical protein [Archaeoglobus fulgid...   129  4e-29
pir||A72497 hypothetical protein APE2615 - Aeropyrum pernix (str...   109  7e-23
sp|Q50697|YM65_MYCTU HYPOTHETICAL 41.9 KDA PROTEIN RV2265 >gi|74...   107  3e-22
pir||E75048 multidrug resistance protein PAB0913 - Pyrococcus ab...    90  5e-17
gb|AAG18975.1| (AE004998) multidrug resistance protein homolog; ...    90  5e-17
pir||H71070 hypothetical protein PH1260 - Pyrococcus horikoshii ...    86  6e-16
pir||G64494 quinolone resistance protein norA homolog - Methanoc...    86  8e-16
pir||D75094 transport protein, permease PAB0761 - Pyrococcus aby...    86  8e-16
gb|AAK41391.1| Conserved hypothetical protein [Sulfolobus solfat...    83  5e-15
gi|11498923 multidrug resistance protein [Archaeoglobus fulgidus...    81  2e-14
gb|AAK41264.1| Transport conserved hypothetical protein [Sulfolo...    79  1e-13
gb|AAB31949.1| (S74031) NorA {ISP794, quinolone resistance} [Sta...    77  3e-13
sp|P21191|NORA_STAAU QUINOLONE RESISTANCE NORA PROTEIN >gi|97835...    77  4e-13
pir||D71112 hypothetical protein PH0667 - Pyrococcus horikoshii ...    75  1e-12
emb|CAC11594.1| (AL445064) sugar transport protein related prote...    73  4e-12
sp|P54559|YQJV_BACSU HYPOTHETICAL 44.7 KD PROTEIN IN GLNQ-ANSR I...    71  2e-11
pir||D71144 hypothetical protein PH0367 - Pyrococcus horikoshii ...    70  4e-11
dbj|BAA36484.1| (AB019536) NorA [Staphylococcus aureus]                69  6e-11

>pir||E75042 transporter (major facilitator family) related PAB0874 - Pyrococcus
           abyssi (strain Orsay) >gi|5458747|emb|CAB50234.1|
           (AJ248287) TRANSPORTER (MAJOR FACILITATOR FAMILY)
           related [Pyrococcus abyssi]
           Length = 392
           
 Score =  763 bits (1948), Expect = 0.0
 Identities = 392/392 (100%), Positives = 392/392 (100%)

Query: 1   MKERKVFGISWNVFLLGLVSFLNDMSSEMIAPIVPSYLTDILKIGKLASGSIMGLIESLS 60
           MKERKVFGISWNVFLLGLVSFLNDMSSEMIAPIVPSYLTDILKIGKLASGSIMGLIESLS
Sbjct: 1   MKERKVFGISWNVFLLGLVSFLNDMSSEMIAPIVPSYLTDILKIGKLASGSIMGLIESLS 60

Query: 61  SLFKVLFGYISDKFRKRKAFVALGYLISTISKGALAVTHSWWDFLILRILDRIGKGIRTA 120
           SLFKVLFGYISDKFRKRKAFVALGYLISTISKGALAVTHSWWDFLILRILDRIGKGIRTA
Sbjct: 61  SLFKVLFGYISDKFRKRKAFVALGYLISTISKGALAVTHSWWDFLILRILDRIGKGIRTA 120

Query: 121 PRDALIAESSEKGKSGKSFGFHRMMDTLGAVAGPLVAMGLLALLANYPKELAYRYIFLIS 180
           PRDALIAESSEKGKSGKSFGFHRMMDTLGAVAGPLVAMGLLALLANYPKELAYRYIFLIS
Sbjct: 121 PRDALIAESSEKGKSGKSFGFHRMMDTLGAVAGPLVAMGLLALLANYPKELAYRYIFLIS 180

Query: 181 AVPGVIGVLIVLLLVKDKGSEVKKKIKGISALKSSNLRIFLVIVAIAALGRYSYAFTLWK 240
           AVPGVIGVLIVLLLVKDKGSEVKKKIKGISALKSSNLRIFLVIVAIAALGRYSYAFTLWK
Sbjct: 181 AVPGVIGVLIVLLLVKDKGSEVKKKIKGISALKSSNLRIFLVIVAIAALGRYSYAFTLWK 240

Query: 241 AEELGYSVFQGLGFYALFNVIYALSAYPIGYYSDKVGKKIIITIGFGIAGLASLIFAYAN 300
           AEELGYSVFQGLGFYALFNVIYALSAYPIGYYSDKVGKKIIITIGFGIAGLASLIFAYAN
Sbjct: 241 AEELGYSVFQGLGFYALFNVIYALSAYPIGYYSDKVGKKIIITIGFGIAGLASLIFAYAN 300

Query: 301 NLPTLLLAFVLYGLYMAIEDTIPRAYMADLAKEFEKGTVIGAYHTVFGVFVFPASIIVGY 360
           NLPTLLLAFVLYGLYMAIEDTIPRAYMADLAKEFEKGTVIGAYHTVFGVFVFPASIIVGY
Sbjct: 301 NLPTLLLAFVLYGLYMAIEDTIPRAYMADLAKEFEKGTVIGAYHTVFGVFVFPASIIVGY 360

Query: 361 LWQTYSLTVGFLYSAVMNVIAMIMMALLIKES 392
           LWQTYSLTVGFLYSAVMNVIAMIMMALLIKES
Sbjct: 361 LWQTYSLTVGFLYSAVMNVIAMIMMALLIKES 392


>pir||G71118 hypothetical protein PH0718 - Pyrococcus horikoshii
           >gi|3257126|dbj|BAA29809.1| (AP000003) 398aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 398
           
 Score =  667 bits (1702), Expect = 0.0
 Identities = 330/390 (84%), Positives = 362/390 (92%)

Query: 2   KERKVFGISWNVFLLGLVSFLNDMSSEMIAPIVPSYLTDILKIGKLASGSIMGLIESLSS 61
           KERK+ GISWNVFLLGLVSFLNDMSSEMIAPIVP+YLTDILK+GKLASGSIMGLIESLSS
Sbjct: 6   KERKIAGISWNVFLLGLVSFLNDMSSEMIAPIVPTYLTDILKMGKLASGSIMGLIESLSS 65

Query: 62  LFKVLFGYISDKFRKRKAFVALGYLISTISKGALAVTHSWWDFLILRILDRIGKGIRTAP 121
           LFKV+FGYISD FRKRK FVALGYL+STI+KGALA+THSWWDFL LRILDRIGKGIRTAP
Sbjct: 66  LFKVIFGYISDVFRKRKTFVALGYLLSTIAKGALALTHSWWDFLTLRILDRIGKGIRTAP 125

Query: 122 RDALIAESSEKGKSGKSFGFHRMMDTLGAVAGPLVAMGLLALLANYPKELAYRYIFLISA 181
           RDALIAESSEKGKSGKSFGFHRMMDTLGAV GPLVA+GLLALL+ YPKELAYRYIFLISA
Sbjct: 126 RDALIAESSEKGKSGKSFGFHRMMDTLGAVTGPLVAVGLLALLSKYPKELAYRYIFLISA 185

Query: 182 VPGVIGVLIVLLLVKDKGSEVKKKIKGISALKSSNLRIFLVIVAIAALGRYSYAFTLWKA 241
           +PG IGVLIV+ LVKD+G  VKKKIK IS+LKS +LR FL +VAIAALGRYSYAFTLWK 
Sbjct: 186 IPGAIGVLIVIFLVKDRGGIVKKKIKEISSLKSPHLRAFLAVVAIAALGRYSYAFTLWKV 245

Query: 242 EELGYSVFQGLGFYALFNVIYALSAYPIGYYSDKVGKKIIITIGFGIAGLASLIFAYANN 301
           +ELGYS+FQGL FYALFNVIYAL+AYPIG YSDKVGKK IIT GFGIAGLASL+FAY+ +
Sbjct: 246 KELGYSIFQGLEFYALFNVIYALAAYPIGSYSDKVGKKKIITTGFGIAGLASLLFAYSKS 305

Query: 302 LPTLLLAFVLYGLYMAIEDTIPRAYMADLAKEFEKGTVIGAYHTVFGVFVFPASIIVGYL 361
           L  L+LAF+LYG+YMAIEDTIPRAYMADLAKE+EKGT+IG YHTVFG+FVFPASIIVGYL
Sbjct: 306 LAMLMLAFILYGVYMAIEDTIPRAYMADLAKEYEKGTIIGMYHTVFGIFVFPASIIVGYL 365

Query: 362 WQTYSLTVGFLYSAVMNVIAMIMMALLIKE 391
           WQTYSL +GFLY++VMN IAMI+M   +KE
Sbjct: 366 WQTYSLEIGFLYASVMNFIAMILMGTFVKE 395


>pir||D64464 hypothetical protein MJ1317 - Methanococcus jannaschii
           >gi|1591956|gb|AAB99324.1| (U67571) hypothetical protein
           [Methanococcus jannaschii]
           Length = 398
           
 Score =  269 bits (680), Expect = 5e-71
 Identities = 158/388 (40%), Positives = 236/388 (60%), Gaps = 17/388 (4%)

Query: 9   ISWNVFLLGLVSFLNDMSSEMIAPIVPSYLTDILKIGKLASGSIMGLIESLSSLFKVLFG 68
           +S NV+LLG  SFLNDMSSEMI PI+P  +T +   G L+ G + GL E +S++  VL G
Sbjct: 20  LSKNVYLLGFTSFLNDMSSEMIMPILPMLITSVGG-GSLSIGLVGGLREFISNILMVLIG 78

Query: 69  YISDKFRKRKAFVALGYLISTISKGALAVTHSWWDFLILRILDRIGKGIRTAPRDALIAE 128
           Y SDK RKRK FV LGYL S++ K  L ++ SW   +I   L+R+GKGIRTAPRDA+I+E
Sbjct: 79  YCSDKVRKRKIFVVLGYLTSSMFKLLLGLSKSWLGAVIFSSLERMGKGIRTAPRDAIISE 138

Query: 129 SSEKGKSGKSFGFHRMMDTLGAVAGPLVAMGLLALLANYPKELAYRYIFLISAVPGVIGV 188
           S  K   GK FG  R  DT GA+ G  +++  +  L     + ++  I LI+AV G +  
Sbjct: 139 SMPK-TLGKGFGIQRAFDTAGAILGSTLSLLFILYL-----QYSFNQIILIAAVIGFL-T 191

Query: 189 LIVLLLVKDKGSEVKKKIKGISALKS--SNLRIFLVIVAIAALGRYSYAFTLWKAEEL-- 244
           LI L  VK+K S    KI     +K+    L++F++I AI  L  +SY F + +A+E   
Sbjct: 192 LIPLYFVKEKPSPSNNKITFRVGIKNLPKELKLFILISAIFTLSNFSYMFYILRAQEFLM 251

Query: 245 ----GYSVFQGLGFYALFNVIYALSAYPIGYYSDKVGKKIIITIGFGIAGLASLIFAYAN 300
                 ++   +  Y L+N+ YA  + P G  SDK+G+K ++TIG+ + G+ SL FAY  
Sbjct: 252 IVDEKMAIIIPIALYILYNIFYATFSIPFGILSDKIGRKSVLTIGYIVYGIVSLGFAYFI 311

Query: 301 NLPTLLLAFVLYGLYMAIEDTIPRAYMADLAKEFEKGTVIGAYHTVFGVFVFPASIIVGY 360
           +  +L+L F LYG+  A+     +AY++DL+ E  + T +G ++TV G+   PAS+I GY
Sbjct: 312 SQKSLILLFALYGIAYALFAGNQKAYVSDLSSEDIRATALGLFYTVVGLTSLPASLIAGY 371

Query: 361 LWQTYSLTVGFLYSAVMNVIAMIMMALL 388
           LW+  S  + FLY +V+ +I+ +++  +
Sbjct: 372 LWK-ISPEMTFLYGSVLAIISGLLLLFI 398


>gb|AAD38864.1| (L09121) hypothetical protein [Thermus thermophilus]
           Length = 385
           
 Score =  221 bits (558), Expect = 9e-57
 Identities = 139/380 (36%), Positives = 205/380 (53%), Gaps = 28/380 (7%)

Query: 24  DMSSEMIAPIVPSYLTDILKIGKLASGSIMGLIESLSSLFKVLFGYISDKFRKRKAFVAL 83
           D++SEM  P++P +L   L  G    G + G+ E+ +SLFKV+ G +SD+  +R+ F+ L
Sbjct: 2   DVASEMAYPLLPLFLAS-LGAGPGTIGLVEGVAEATASLFKVVGGRLSDRLGRRRPFLLL 60

Query: 84  GYLISTISKGALAVTHSWWDFLILRILDRIGKGIRTAPRDALIAESSEKGKSGKSFGFHR 143
           GY +  + +  LA+  S +  L+ R LDR GKG+RTAPRDALIAES+ K   G+++G HR
Sbjct: 61  GYGLPALFRPLLALAQSPFHVLLYRFLDRTGKGLRTAPRDALIAESAPKEALGRAYGLHR 120

Query: 144 MMDTLGAVAGPLVAMGLLALLANYPKELAYRYIFLISAVPGVIGVLIVLLLVKDKGSEVK 203
            +DTLGA  GP +A  LL L       L +R +F +SA+P ++  L++  + +       
Sbjct: 121 SLDTLGATLGPFLAFLLLPL-------LGFRGVFWLSALPALLAFLLLFAVRETPRPPSP 173

Query: 204 KKIKGISALKSSNLRIFLVIVAIAALGRYSYAFTLWKAEELGYSVFQGLGFYALFNVIYA 263
                +  L S   R FL++  + AL   S AF L + +ELG S  +    Y L+N++YA
Sbjct: 174 LPPLALGHL-SPGYRRFLLVSGLFALALSSNAFLLLRLKELGLSQEEVALAYTLYNLLYA 232

Query: 264 LSAYPIGYYSDKVGKKIIITIGFGIAGLASLIFAYANNLPTLLLAFVLYGLYMAIEDTIP 323
           L AYP+G  +D+VG   ++  GFG+  L  L FA+A      L    LY LY A  +   
Sbjct: 233 LLAYPLGGLADRVGLGRMVATGFGLYALVYLGFAWARTAFWALGFLFLYALYSAAFEGAN 292

Query: 324 RAYMADLAKEF-------------------EKGTVIGAYHTVFGVFVFPASIIVGYLWQT 364
           RAY+A L  E                     K   IG YHTV GV + PAS++ G LWQ 
Sbjct: 293 RAYLATLVPEEAKAGAIGLYHTVVGVLLLPAKAGAIGLYHTVVGVLLLPASLLFGLLWQA 352

Query: 365 YSLTVGFLYSAVMNVIAMIM 384
           +     FL  A + + A+++
Sbjct: 353 FGAAAAFLTGAALALGALLL 372


>pir||T45544 hypothetical protein 3 [imported] - Klebsiella pneumoniae
           transposon Tn5711 >gi|3758825|emb|CAA09859.1| (AJ011907)
           hypothetical protein [Klebsiella pneumoniae]
           Length = 404
           
 Score =  189 bits (476), Expect = 4e-47
 Identities = 120/381 (31%), Positives = 204/381 (53%), Gaps = 10/381 (2%)

Query: 13  VFLLGLVSFLNDMSSEMIAPIVPSYLTDILKIGKLASGSIMGLIESLSSLFKVLFGYISD 72
           V+++G VS L D+SSEMI  ++P ++   L    L  G I GL E+ + + KV  G ISD
Sbjct: 15  VWVVGCVSLLMDISSEMIHSLLPLFMATTLGASVLVIGLIEGLAEATALIVKVFSGVISD 74

Query: 73  KFRKRKAFVALGYLISTISKGALAVTHSWWDFLILRILDRIGKGIRTAPRDALIAESSEK 132
              KRK    LGY +  +SK   A+  S    L  R+ DR+GKGIR  PRDAL+A+ +  
Sbjct: 75  WLGKRKGLALLGYGLGALSKPLFAIASSSGMVLTARLTDRLGKGIRGRPRDALVADVTPP 134

Query: 133 GKSGKSFGFHRMMDTLGAVAGPLVAMGLLALLANYPKELAYRYIFLISAVPGVIGVLIVL 192
              G +FG  + +DT+GA  GPL+A+GL+ L  +      +R IF ++ +PG++ V ++ 
Sbjct: 135 ELRGAAFGLRQSLDTIGAFLGPLLAVGLMLLWQD-----DFRAIFWVAVIPGLMAVALLF 189

Query: 193 L-LVKDKGSEVKKKIKGISA--LKSSNLRIFLVIV--AIAALGRYSYAFTLWKAEELGYS 247
           L L + + + V K+   +S   LK      + VI    I  L R+S AF + +A+E+   
Sbjct: 190 LGLHEPRTAVVHKRTNPVSRANLKRLGQSTWWVIALGGIFTLARFSEAFLVLRAQEVHIP 249

Query: 248 VFQGLGFYALFNVIYALSAYPIGYYSDKVGKKIIITIGFGIAGLASLIFAYANNLPTLLL 307
           +          N++Y+ SAYP G  +D++  + ++ +G  +  +A ++ A + +   +L+
Sbjct: 250 LALIPLVMVAMNLLYSFSAYPFGKLADRMSHRHLLQLGLVVLVVADIVLALSTHWVGVLI 309

Query: 308 AFVLYGLYMAIEDTIPRAYMADLAKEFEKGTVIGAYHTVFGVFVFPASIIVGYLWQTYSL 367
              L+G++M +   +  A +AD +    +GT  G +  V GV +  AS   G LW T+  
Sbjct: 310 GVALWGVHMGMTQGLLAAMIADSSPADLRGTAYGLFSLVSGVALLLASAGAGLLWTTWGS 369

Query: 368 TVGFLYSAVMNVIAMIMMALL 388
              F+  A + +I ++ + ++
Sbjct: 370 ESTFIAGAAICLITLLYLRVV 390


>pir||A72413 conserved hypothetical protein - Thermotoga maritima (strain MSB8)
           >gi|4980623|gb|AAD35224.1|AE001699_1 (AE001699)
           conserved hypothetical protein [Thermotoga maritima]
           Length = 384
           
 Score =  150 bits (374), Expect = 3e-35
 Identities = 109/380 (28%), Positives = 187/380 (48%), Gaps = 20/380 (5%)

Query: 13  VFLLGLVSFLNDMSSEMIAPIVPSYLTDILKIGKLASGSIMGLIESLSSLFKVLFGYISD 72
           + LLGLVS   D++ E    I+  ++   L     A G  +GL E     F+++ G +SD
Sbjct: 10  IVLLGLVSLFADVTYEGARSIIGPFMKT-LGASAAALGFAVGLGELTGYAFRLISGILSD 68

Query: 73  KFRKRKAFVALGYLISTISKGALAVTHSWWDFLILRILDRIGKGIRTAPRDALIAESSEK 132
           K RK   F  LGY I+  +  ALA   +W   L+L I +R GK +RT  RD L++ +SE+
Sbjct: 69  KTRKYWLFTILGYAINLFAVPALAFAGNWQTALVLIIAERFGKALRTPARDVLLSFASEE 128

Query: 133 GKSGKSFGFHRMMDTLGAVAGPLVAMGLLALLANYPKELAYRYIFLISAVPGVIGVLIVL 192
              GK FG H  +D +GA+ GPL     LA       E +YR+ F I  +P ++ ++++L
Sbjct: 129 VGMGKGFGIHEALDQIGAILGPLALTFALAF------EKSYRFCFFILLIPALVAMVLLL 182

Query: 193 ---LLVKDKGSEVKKKIKGISALKSSNLRIFLVIVAIAALGRYSYAFTLW--KAEELGYS 247
              +         KKK   +          +L IV++ A     +    +  K+ E+   
Sbjct: 183 TARITFPALQEMKKKKDSPVDRNLGKTYWFYLAIVSMVAFAFADFPIIAYHMKSFEVAKD 242

Query: 248 VFQGLGFYALFNVIYALSAYPIGYYSDKVGKKIIITIGFGIAGLASL--IFAYANNLPTL 305
            F     Y+L   + A++A   G+  DK G    + + + +  L+S   + +++N+ P +
Sbjct: 243 FFVP-ATYSLAMAVDAVAALVFGHLFDKKG---FVALAYAVL-LSSFFPVLSFSNSFPLI 297

Query: 306 LLAFVLYGLYMAIEDTIPRAYMADLAKEFEKGTVIGAYHTVFGVFVFPASIIVGYLWQTY 365
               +L+G+ M  +++I RA +A +    ++G   G + TV+GVF F  S I+G L+   
Sbjct: 298 FAGVILWGIGMGAQESIMRAVVAKIVPAEKRGFAYGMFFTVYGVFWFFGSWIMGTLYDIN 357

Query: 366 SLTVGFLYSAVMNVIAMIMM 385
              +  L+S V+   A +++
Sbjct: 358 RFYL-ILFSFVIQFAAALLL 376


>pir||G69201 conserved hypothetical protein MTH761 - Methanobacterium
           thermoautotrophicum (strain Delta H)
           >gi|2621850|gb|AAB85264.1| (AE000854) conserved protein
           [Methanobacterium thermoautotrophicum]
           Length = 383
           
 Score =  130 bits (323), Expect = 3e-29
 Identities = 110/386 (28%), Positives = 184/386 (47%), Gaps = 33/386 (8%)

Query: 13  VFLLGLVSFLNDMSSEMIAPIVPSYLTDILKIGKLASGSIMGLIESLSSLFKVLFGYISD 72
           + +LG+VS   DM+ E    I   +L   L       G   G  E    L + L GYISD
Sbjct: 8   IVILGIVSLFADMTYEGGRGITGPFLA-FLGASAFMVGFAAGFGELSGYLVRFLSGYISD 66

Query: 73  KFRKRKAFVALGYLISTISKGALAVTHSWWDFLILRILDRIGKGIRTAPRDALIAESSEK 132
           +  +       GYLI+ ++   LA   +W   ++L IL+R+GKG+RT PRDA+++ +S  
Sbjct: 67  RTGRYWLITFAGYLINLLAVPLLAFAGNWQVAVLLIILERLGKGLRTPPRDAMLSYASYD 126

Query: 133 GKSGKSFGFHRMMDTLGAVAGPLVAMGLLALLANYPKELAYRYIFLISAVPGVIGVLIVL 192
              G  FG H  +D +GAVAGPL+   +LA    Y +     ++ L++     I VL+  
Sbjct: 127 MGHGAGFGLHEALDQIGAVAGPLMVFIVLASGGGYRE----GFLVLLAPATIAIAVLVTG 182

Query: 193 LLVKDKGSEVKKKIKGISALKSSNLRIFLVIVAIAALGRYSYAFTLWKAEELGY-----S 247
            L+  + SE++   +           ++L  V   ALG   +         +GY     S
Sbjct: 183 YLMFPRPSELEASGEIDYRDFRGAYWLYLASVCFVALGYADFPL-------IGYHLGVRS 235

Query: 248 VFQGLG---FYALFNVIYALSAYPIGYYSDKVGKKIIITIGFGIAGLASLIFA---YANN 301
           V         YAL  +  ALSA   G Y D+ G +++      +A L S+ +A   +   
Sbjct: 236 VLDPSNIPIIYALAMLTDALSALVSGRYFDRYGFRVM-----ALAVLVSMFYAPLSFLGG 290

Query: 302 LPTLLLAFVLYGLYMAIEDTIPRAYMADLAKEFEKGTVIGAYHTVFGVFVFPASIIVGYL 361
               ++  VL+G+ M  ++++ RA ++  +    +G+  G ++T+FGV  F  S+I+ YL
Sbjct: 291 SWAAVMGAVLWGVGMGAQESVMRAAVSAFSSPERRGSAYGTFNTIFGVAWFSGSLIMSYL 350

Query: 362 WQTYSLTVGFL--YSAVMNVIAMIMM 385
              Y L+V  L  +S +    A++++
Sbjct: 351 ---YGLSVPGLVAFSIITQSAALVIL 373


>gi|11499136 conserved hypothetical protein [Archaeoglobus fulgidus]
           >gi|7430263|pir||D69442 conserved hypothetical protein
           AF1541 - Archaeoglobus fulgidus
           >gi|2649020|gb|AAB89705.1| (AE000996) conserved
           hypothetical protein [Archaeoglobus fulgidus]
           Length = 372
           
 Score =  129 bits (322), Expect = 4e-29
 Identities = 107/376 (28%), Positives = 183/376 (48%), Gaps = 18/376 (4%)

Query: 13  VFLLGLVSFLNDMSSEMIAPIVPSYLTDILKIGKLASGSIMGLIESLSSLFKVLFGYISD 72
           + L+GLVS   D++ E    IV  YL     +   A G I G  E      ++L GYI+D
Sbjct: 8   ILLMGLVSLFGDITYEGARSIVGPYLATF-GLTAAAIGLITGFGEFAGYGLRLLSGYIAD 66

Query: 73  KFRKRKAFVALGYLISTISKGALAVTHSWWDFLILRILDRIGKGIRTAPRDALIAESSEK 132
           +         LGY +  ++   LA  + WW   +L + +R+GK IRT  RDA+++ ++++
Sbjct: 67  RTGNYWLLTFLGYSL-ILAIPLLAFANYWWIAALLIVAERLGKAIRTPARDAMLSFATKQ 125

Query: 133 GKSGKSFGFHRMMDTLGAVAGPLVAMGLLALLANYPKELAYRYIFLISAVPGVIGVLIVL 192
              G  FG H  MD +GAV GPL+   + + LA Y  + A+  +FL    P ++ +L + 
Sbjct: 126 VGRGTGFGIHEAMDQVGAVIGPLI---VFSALAGYTFKEAFIALFL----PALLVILFLF 178

Query: 193 LLVKDKGSEVKKKIKGISALKSSNLRIFLVIVAIAALGRYSYAFTLWKAEELGYSVFQGL 252
              K   +  + +I+   +    +  ++ + V ++  G  S  F L      GY   + +
Sbjct: 179 ATWKLYPTPQRFEIEEQESRVEGSFWLYSLFVFLSVAGFLS--FPLLSYHLAGYVDLKLI 236

Query: 253 G-FYALFNVIYALSAYPIGYYSDKVGKKIIITIGFGIAGLASLI-FAYANNLPTLLLAFV 310
              YAL   I A+SA   G   D++G K ++ +      L  LI  A   ++  +L+   
Sbjct: 237 PLLYALAMGIDAISALISGRCYDRIGLKTLMLVPL----LTPLILLALHPSIIGVLVGVA 292

Query: 311 LYGLYMAIEDTIPRAYMADLAKEFEKGTVIGAYHTVFGVFVFPASIIVGYLWQ-TYSLTV 369
            +G  M + + I RA +ADL    ++ T  G ++TVFGV +     ++GYL+  + +L V
Sbjct: 293 AWGAVMGMHEAITRAAVADLTGVKKRSTAYGVFNTVFGVAMLAGGAVLGYLYDISAALLV 352

Query: 370 GFLYSAVMNVIAMIMM 385
           GF+    +   A ++M
Sbjct: 353 GFVLVVEVAAFATLLM 368


>pir||A72497 hypothetical protein APE2615 - Aeropyrum pernix (strain K1)
           >gi|5106322|dbj|BAA81633.1| (AP000064) 388aa long
           hypothetical protein [Aeropyrum pernix]
           Length = 388
           
 Score =  109 bits (269), Expect = 7e-23
 Identities = 99/345 (28%), Positives = 158/345 (45%), Gaps = 29/345 (8%)

Query: 15  LLGLVSFLNDMSSEMIAPIVPSYLTDILKIGKL--ASGSIMGLIESLSSLFKVLFGYISD 72
           LLGLVS   D++ E    IV  YL + L+ G +  A+ S+  L+  ++ LF  LF Y   
Sbjct: 22  LLGLVSLFADLTYEGARGIVGPYL-EFLEAGLVVAAAVSVGDLVAYVARLFGGLFAYRVG 80

Query: 73  KFRKRKAFVALGYLISTISKGALAVTHSWWDFLILRILDRIGKGIRTAPRDALIAESSEK 132
                   V LGY ++ ++   LA    W +  +L +L+R GKG+R   RDA++AE S  
Sbjct: 81  SSGAYWGLVFLGYTVNLVAVPLLAFAGRWEEAFLLVLLERAGKGVRAPARDAILAEVSGG 140

Query: 133 GKSGKSFGFHRMMDTLGAVAGPLVAMGLLALLANYPKELAYRYIFLISAVPGVIGVLIVL 192
              G  +  H  MD +GA+AGPL+ M  L+          Y  +F +  VP ++ +L++ 
Sbjct: 141 LGRGVVYAVHEAMDQVGAIAGPLLVMAALS------SGFGYSGVFALLGVPALVSLLLLT 194

Query: 193 LLVKDKGSEVKKKIKGISALKSSNLRIFLVIVAIAALGRYSYAFTLWKAEELGYSVFQGL 252
           L        +  ++K              V    AA G     F  W      YSV QG+
Sbjct: 195 L-----AYILYPRLKSAEKPPGGYPPFGRVAPLAAAAGLSMAGFIHWIHASFRYSV-QGV 248

Query: 253 ------GFYALFNVIYALSAYPIGYYSDKVGKKII--ITIGFGIAGLASLIFAYANNLPT 304
                 G YA+  ++ AL+A  +G   DKV + ++  + I    + LA L+ A       
Sbjct: 249 DASLIAGAYAVAMLVDALAALALGVAYDKVTRGVVALVPIVAAASSLAVLLGA------P 302

Query: 305 LLLAFVLYGLYMAIEDTIPRAYMADLAKEFEKGTVIGAYHTVFGV 349
           L LA +L+G+ M    ++ R+ +AD  +   +G   G  +   G+
Sbjct: 303 LALAAILWGVAMGGFQSVFRSVVADSLEPRLRGLGFGVVYFAMGL 347


>sp|Q50697|YM65_MYCTU HYPOTHETICAL 41.9 KDA PROTEIN RV2265 >gi|7430264|pir||E70729
           hypothetical protein Rv2265 - Mycobacterium tuberculosis
            (strain H37RV) >gi|1449355|emb|CAB00970.1| (Z77163)
           hypothetical protein Rv2265 [Mycobacterium tuberculosis]
           Length = 409
           
 Score =  107 bits (264), Expect = 3e-22
 Identities = 90/393 (22%), Positives = 182/393 (45%), Gaps = 36/393 (9%)

Query: 13  VFLLGLVSFLNDMSSEMIAPIVPSYLTDILKIGKLASGSIMGLIESLSSLFKVLFGYISD 72
           V + G+V  L D+  E    I    L  +   G L  G + G+ E+ +   +++ G ++D
Sbjct: 25  VTVFGVVGLLADVVYEGARSITGPLLASLGATG-LVVGVVTGVGEAAALGLRLVSGPLAD 83

Query: 73  KFRKRKAFVALGYLISTISKGALAVTHSWWDFLILRILDRIGKGIRTAPRDALIAESSEK 132
           + R+  A+   GY ++ ++   L +  + W    L I +R+GK +R   +D L++ ++  
Sbjct: 84  RSRRFWAWTIAGYTLTVVTVPLLGIAGALWVACALVIAERVGKAVRGPAKDTLLSHAASV 143

Query: 133 GKSGKSFGFHRMMDTLGAVAGPLVAMGLLALLANYPKELAYRYIFLISAVPGVIGVLIVL 192
              G+ F  H  +D +GA+ GPL   G+LA+  N     AY     +  +PG   + ++L
Sbjct: 144 TGRGRGFAVHEALDQVGAMIGPLTVAGMLAITGN-----AYAPALGVLTLPGGAALALLL 198

Query: 193 LLVK-----DKGSEVKKKIKGISALK----SSNLRIFLVIVAIAALGRYSYAFTLWKAEE 243
            L +     +   +    +   SA +     +   ++    AI  LG  ++    +    
Sbjct: 199 WLQRRVPRPESYEDCPVVLGNPSAPRPWALPAQFWLYCGFTAITMLGFGTFGLLSF---- 254

Query: 244 LGYSVFQGLGFYALFNVIY-------ALSAYPIGYYSDKVGKKIIITIGFGIAGLASLIF 296
             + V  G+   A+  V+Y       AL+A   G+  D+ G K +  +   I  +  ++F
Sbjct: 255 --HMVSHGVLAAAMVPVVYAAAMAADALTALASGFSYDRYGAKTLAVL--PILSILVVLF 310

Query: 297 AYANNLPTLLLAFVLYGLYMAIEDTIPRAYMADLAKEFEKGTVIGAYHTVFGVFVFPASI 356
           A+ +N+  +++  +++G  + I+++  R  +ADL     + +  G +    G        
Sbjct: 311 AFTDNVTMVVIGTLVWGAAVGIQESTLRGVVADLVASPRRASAYGVFAAGLGAATAGGGA 370

Query: 357 IVGYLWQTYSLTVGFLYSAVMNVIAMIMMALLI 389
           ++G+L   Y +++G L   V+ VIA+ +MAL++
Sbjct: 371 LIGWL---YDISIGTL---VVVVIALELMALVM 397


>pir||E75048 multidrug resistance protein PAB0913 - Pyrococcus abyssi  (strain
           Orsay) >gi|5458795|emb|CAB50282.1| (AJ248287) multidrug
           resistance protein [Pyrococcus abyssi]
           Length = 410
           
 Score = 89.7 bits (219), Expect = 5e-17
 Identities = 104/391 (26%), Positives = 171/391 (43%), Gaps = 46/391 (11%)

Query: 12  NVFLLGLVSFLNDMSSEMIAPIVPSYLTDILKIGKLASGS--IMGLIESL----SSLFKV 65
           N+ +  +  F  D +  +  P +  Y+       KL  G+  ++GL+  +    S++F+ 
Sbjct: 27  NILMFAIGMFFADFAWGLGFPYLGVYM-------KLIGGTMFLVGLLSVVYNLTSTIFQY 79

Query: 66  LFGYISDKFRKRKAFVALGYLISTISKGALAVTHSWWDFLILRILD-RIGKGIRTAPRDA 124
            FGY+SDK  KRK F+ LG L S  + G +A+  S    L LR     +G  +  A   A
Sbjct: 80  PFGYLSDKTGKRKPFIILGILASGTTYGLVALITSPILLLGLRAFQGALGASLAPA-HSA 138

Query: 125 LIAESSEKGKSGKSFGFHRMMDTLGAVAGPLVAMGLLALLANYPKELAYRYIFLISAVPG 184
           LI+E S   + G  FGF   ++ LG +AG      ++       K L  + +F+I+++  
Sbjct: 139 LISELSP--RIGSMFGFFGFVENLGFMAGNFAGGYIV-------KTLGMKMMFIITSLVS 189

Query: 185 VIGVLIVLLLVKDKG------------------SEVKKKIKGISALKSSNLRIFLVIVAI 226
           +IG+L  LL +K++G                    V+ K      L    L IF V V +
Sbjct: 190 LIGILF-LLKIKERGRAKAGGDRLIIVKEGRESDRVELKEIAFKKLMKGRLGIFYVAVLL 248

Query: 227 AALGRYS-YAFTLWKAEELGYSVFQGLGFYALFNVIYALSAYPIGYYSDKVGKKIIITIG 285
           A +   + YA      EE     F G   + + ++  ALSA  IG   DK G+K+   + 
Sbjct: 249 AMIASGAVYATVSVYFEEKFGEEFVGY-LFGIDSLSAALSALIIGRLIDKYGEKLFFRLS 307

Query: 286 FGIAGLASLIFAYANNLPTLLLAFVLYGLYMAIEDTIPRAYMADLAKEFEKGTVIGAYHT 345
                +  + +A AN++  + L  +L GL   +       Y+A      E+G  +G  +T
Sbjct: 308 LVGYIITFMGYALANSVIIMALISILSGLKWTMLTNSSSTYVARRVPTSERGQGMGLLNT 367

Query: 346 VFGVFVFPASIIVGYLWQTYSLTVGFLYSAV 376
           +  +      +I G L   +   V  LYS V
Sbjct: 368 MMTLGWVIGPLIGGILADNFGFAV-MLYSTV 397


>gb|AAG18975.1| (AE004998) multidrug resistance protein homolog; YfmO2
           [Halobacterium sp. NRC-1]
           Length = 420
           
 Score = 89.7 bits (219), Expect = 5e-17
 Identities = 89/359 (24%), Positives = 154/359 (42%), Gaps = 27/359 (7%)

Query: 47  LASGSIMGLIESLSSLFKVLFGYISDKFRKRKAFVALGYLISTISKGALAVTHSWWDFLI 106
           L  G ++     L+S  +   G +SD+   RK F+  G ++  ++ GA A    +   L+
Sbjct: 63  LLIGIVLSTFGFLNSFLQPFTGRLSDRTGVRKPFILGGLVLLALASGAYAFVSDYRLLLV 122

Query: 107 LRILDRIGKGIRTAPRDALIAESSEKGKSGKSFGFHRMMDTLGAVAGPLVAMGLLALLAN 166
           LR L  IG  +      AL++E       G +FG       +G   GP++A  +L +   
Sbjct: 123 LRALQGIGAALTVPATVALVSELGTTETRGSNFGVFNTFRLIGFGFGPIIAGVVLEV--- 179

Query: 167 YPKELAYRYIFLISAVPGVIGVLIVLLLV-------KDKGSEVKKKIKGISALKSSNLRI 219
                ++   F ++A   +   ++V L V        D G ++   ++G  A+      +
Sbjct: 180 ----FSFNAAFGVAAAGALTSFVLVELTVDEPDTDGADAGDDLSIAVRGDDAVLDP---V 232

Query: 220 FLVIVAIAALGRYSYAFTLWKAEELG----YSVFQGLGFYA--LFNVIYALSAYPIGYYS 273
           F + +A  A+G     F   +A+  G     S+  G  F A  L NV++ +   PIG  S
Sbjct: 233 FALGIATVAMGICIAMFATLEAKINGKLDQSSILFGAEFGAVTLANVMFQV---PIGTAS 289

Query: 274 DKVGKKIIITIGFGIAGLASLIFAYANNLPTLLLAFVLYGLYMAIEDTIPRAYMADLAKE 333
           D  G++  I  GF I   A++   YA    T++LA  + G+ +A       A   DLA  
Sbjct: 290 DTYGRRPFIIAGFIILIPATIAQGYAPTPATMILARFVQGIAVAAVFAPSLAVAGDLAGA 349

Query: 334 FEKGTVIGAYHTVFGVFVFPASIIVGYLWQTYSLTVGFLYSAVMNVIAMIMMALLIKES 392
            E G+ +      FG+      +  G+L   Y L   FL   V+  +A+ ++   + E+
Sbjct: 350 GESGSTLAVLTMGFGLGTAIGPLASGFL-AAYGLATPFLIGGVLAALALAVVYTQVYET 407


>pir||H71070 hypothetical protein PH1260 - Pyrococcus horikoshii
           >gi|3257679|dbj|BAA30362.1| (AP000005) 372aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 372
           
 Score = 86.2 bits (210), Expect = 6e-16
 Identities = 96/380 (25%), Positives = 171/380 (44%), Gaps = 34/380 (8%)

Query: 13  VFLLGLVSFLNDMSSEMIAPIVPSYLTDILKIGKLASGSIMGLIESLSSLFKVLFGYISD 72
           + +L  + ++ + S  M  P +   L   L I     G +M  +    SL +V  GYI D
Sbjct: 6   ILILISLGWIFNYSHRMAVPSLAPILMKELSINNTEVGLLMTALLLPYSLIQVPAGYIGD 65

Query: 73  KFRKRKAFVALGYLISTISKGALAVTHSWWDFLILRILDRIGKGIRTAPRDALIAESSEK 132
           K   RK  + L  L  +IS   + +  ++WD + +R L     G+  AP  +LI+E   +
Sbjct: 66  KI-GRKKLLTLSILGYSISSALIVLARNYWDLVAIRALYGFFAGLYYAPATSLISELFRE 124

Query: 133 GKSGKSFGFHRMMDTLGAVAGPLVAMGLLALLANYPKELAYRYIFLI-SAVPGVIGVLIV 191
            K G + GF  +   +G+   PL+ +  +AL+ N      +R  FL+ S +  ++GVL+V
Sbjct: 125 -KKGSALGFFMIGPAIGSGITPLIVVP-VALMLN------WRLSFLVLSIMSSIVGVLLV 176

Query: 192 LLLVKDKGSEVKKK----IKGISALKSSNLRIFLVIVAIAALGRYSYAFTLWKAEELGYS 247
            L VK +  EV++      KG+  L  +N   FL + A  A+  +  ++ + K    G  
Sbjct: 177 -LTVKGEPVEVERAKFSIPKGVLLLSLAN---FLGLGAFFAMLTFLVSYLVSK----GVD 228

Query: 248 VFQGLGFYALFNVIYALSAYPIGYYSDKVGKKIIITIGFGIAGLASLIFAYANNLPTLLL 307
           + +    +++ +++    +   G+  D  GK  +         L  LI  +   L  + L
Sbjct: 229 IKEASLMFSILSLVGVFGSVTAGFLYDYAGKVSVFLAYLLNFLLTFLIIVFPTPLLLIPL 288

Query: 308 AFVLYGLYMAIEDTIPRAYMADLAKEFEKGTVIGAYHTV--FGVFVFPASI-----IVGY 360
             VLY +       I  AY A+ A++   G V+G  + V  FG    P  +      +GY
Sbjct: 289 GLVLYSV-----GGIITAYTAEKAEKSNLGVVMGFVNMVGFFGATTGPYVVGFLIDKLGY 343

Query: 361 LWQTYSLTVGFLYSAVMNVI 380
                S+ + +L SA++ ++
Sbjct: 344 SRALLSVPLAYLVSALIIIV 363


>pir||G64494 quinolone resistance protein norA homolog - Methanococcus
           jannaschii >gi|1592184|gb|AAB99579.1| (U67596)
           multidrug-efflux transporter (bmr1) [Methanococcus
           jannaschii]
           Length = 386
           
 Score = 85.8 bits (209), Expect = 8e-16
 Identities = 90/386 (23%), Positives = 162/386 (41%), Gaps = 14/386 (3%)

Query: 12  NVFLLGLVSFLNDMSSEMIAPIVPSYLTDILKIGKLASGSIMGLIESLSSLFKVLFGYIS 71
           NVF++ + +F   +    IAPI+  Y    L    L  G I G      ++ ++  G +S
Sbjct: 7   NVFVIWITTFTTMLGVGFIAPIMAIY-AQTLGATNLEIGLIFGSFALARTVAQIPVGVLS 65

Query: 72  DKFRKRKAFVALGYLISTISKGALAVTHSWWDFLILRILDRIGKGIRTAPRDALIAESSE 131
           D + K K F+  G     +S        +   FLI+RI   I     T    + IA  + 
Sbjct: 66  DIYGK-KFFIVCGTFFYGVSTLMYNFVSTVLGFLIVRIFTGIFSAFVTPVAGSYIAAIAP 124

Query: 132 KGKSGKSFGFHRMMDTLGAVAGPLVAMGLLALLANYPKELAYRYIFLISAVPGVIGVLIV 191
           K + G+  G      TLG   GP +  G+LA +  Y  ++ + +   +  +  +I  + +
Sbjct: 125 KTRLGEYMGIFNSAITLGFGIGPFIG-GILADM--YGIKMPFYFCGFLGILAAIISYMKL 181

Query: 192 LLLVKDKGSEVKKKIKGISAL------KSSNLRI-FLVIVAIAALGRYSYAFTLWKAEEL 244
             +V +K  E K  +K IS L      K+ N    F++ V+   +    YA+    A   
Sbjct: 182 EDIVFNKNKE-KIDVKKISTLFSFEFLKNRNFSSSFIINVSNVMINAGIYAYLALYAINY 240

Query: 245 GYSVFQGLGFYALFNVIYALSAYPIGYYSDKVGKKIIITIGFGIAGLASLIFAYANNLPT 304
             ++ Q     AL N++ AL     G   DK+G  I+I IG  I      + + +    T
Sbjct: 241 NITISQVGFMIALTNILMALLQRSFGKLYDKLGN-IMIIIGIFIISFGMYLLSTSTTFLT 299

Query: 305 LLLAFVLYGLYMAIEDTIPRAYMADLAKEFEKGTVIGAYHTVFGVFVFPASIIVGYLWQT 364
           +L +  +  +  +I  T   +          KG  +G + T   + +F  ++  G+L   
Sbjct: 300 ILASLTIIAVGSSISSTATTSLAVKDIPTHRKGEAMGLFTTSINIGMFIGAVSFGFLADI 359

Query: 365 YSLTVGFLYSAVMNVIAMIMMALLIK 390
             +   + +SA+ +++  I+  L I+
Sbjct: 360 LGIANMYKFSAIFSIVVGIISYLRIE 385


>pir||D75094 transport protein, permease PAB0761 - Pyrococcus abyssi  (strain
           Orsay) >gi|5458569|emb|CAB50057.1| (AJ248286) TRANSPORT
           PROTEIN, permease [Pyrococcus abyssi]
           Length = 372
           
 Score = 85.8 bits (209), Expect = 8e-16
 Identities = 92/392 (23%), Positives = 177/392 (44%), Gaps = 41/392 (10%)

Query: 13  VFLLGLVSFLNDMSSEMIAPIVPSYLTDILKIGKLASGSIMGLIESLSSLFKVLFGYISD 72
           + +L  + ++ + S  M  P +   +   L I     G +M  +    SL +V  GYI D
Sbjct: 6   ILILISLGWIFNYSHRMAVPSLAPIIMKDLGINNAEIGLLMTSLLLPYSLIQVPAGYIGD 65

Query: 73  KFRKRKAFVA--LGYLISTISKGALAVTHSWWDFLILRILDRIGKGIRTAPRDALIAESS 130
           K  ++K      LGY   ++S   + +T  +WD + +R L     G+  AP  ALI+E  
Sbjct: 66  KIGRKKLLTISILGY---SLSSALIVLTRDYWDLVTVRALYGFFAGLYYAPATALISELF 122

Query: 131 EKGKSGKSFGFHRMMDTLGAVAGPLVAMGLLALLANYPKELAYRYIFLI-SAVPGVIGVL 189
            + K G + GF  +   +G+   PL+ + +          L++RY FL+ S +  ++G  
Sbjct: 123 RERK-GSALGFFMVGPAIGSGITPLIVVPVAL-------TLSWRYAFLVLSIMSSIVG-- 172

Query: 190 IVLLLVKDKGSEVKKKIKGISALKSSNLRIFLVIVAIAALGRYSYAFTLWKAEELGYSVF 249
            +LL+V  KG  +  K++G+   K       L +     LG +    T      + Y V 
Sbjct: 173 -ILLMVAIKGEPI--KVEGVK-FKIPRGVFLLSLANFLGLGAFFAMLTFL----VSYLVS 224

Query: 250 QGLG------FYALFNVIYALSAYPIGYYSDKVGKKIIITIGFGIAGLAS-LIFAYANNL 302
           +G+G       +++ +++  L +   G+  D +G K+ + + + +  L + L+    + L
Sbjct: 225 RGVGMEKASLMFSMLSLVGILGSIIAGFLYDHLG-KVSVLLAYALNSLLTFLVIVIPSPL 283

Query: 303 PTLLLAFVLYGLYMAIEDTIPRAYMADLAKEFEKGTVIGAYHTV--FGVFVFPASIIVGY 360
             + L  VLY +       I  AY ++ A     G V+G  + V  FG  + P   IVG+
Sbjct: 284 FLIPLGLVLYSV-----GGIMTAYTSEKASRENLGVVMGFVNMVGFFGATIGP--YIVGF 336

Query: 361 LWQTYSLTVGFLYSAVMNVIAMIMMALLIKES 392
           L      ++  L   +  +++ +++ L ++++
Sbjct: 337 LIDRLGYSLALLSVPLAYLVSAVIIGLDLRKT 368


>gb|AAK41391.1| Conserved hypothetical protein [Sulfolobus solfataricus]
           Length = 383
           
 Score = 83.1 bits (202), Expect = 5e-15
 Identities = 81/382 (21%), Positives = 169/382 (44%), Gaps = 17/382 (4%)

Query: 13  VFLLGLVSFLNDMSSEMIAPIVPSYLTDILKIGKLASGSIMGLIESLSSLFKVLFGYISD 72
           V  +   +F  D+  + +    P     I K      G    L   + ++     G   D
Sbjct: 8   VLKISFSAFFADLGYQAVVASFPIIFVLIFKAPIPLYGFAEALNYGIGTVMAYAGGLAGD 67

Query: 73  KFRKRKAFVALGYLISTISKGALAVTHSWWDFLILRILDRIGKGIRTAPRDALIAESSEK 132
           +F +++  +    LI   S   + ++  +   LI  ++    +  R+ PR A++AE +  
Sbjct: 68  RFGRKRIAILGNVLILFTS--LIGLSRDYIQALIFFMIGWWFRNFRSPPRRAMMAEVTSP 125

Query: 133 GKSGKSFGFHRMMDTLGAVAGPLVAMGLLALLANYPKELAYRYIFLISAVPGVIGVLIVL 192
            +  ++FG    +D    +AG L+A+  L +L      ++  ++ L +++P ++  +++ 
Sbjct: 126 EERSEAFGILHSLD----IAGALIAIIYLTVLLYL--RVSIFFVLLFTSIPLLMSTIVLT 179

Query: 193 LLVKDKGSEVKKKIKGISALKSSNLRIFLVIV---AIAALGRYSYAFTLWKAEELGYSVF 249
           ++   K SE  K+ +  S  K +  R+F  ++         +YS+ F +    E+    +
Sbjct: 180 MVNAGKKSEKAKRKEAES--KITQKRVFWTLILSTMFFGFSQYSFGFPILTTTEITGKEY 237

Query: 250 QGLGFYALFNVIYALSAYPIGYYSDKVGKKIIITIGFGIAGLASLIFAYANNLPTLLL-- 307
            G+  Y +F    +L  Y  G    K  + +   +G+ I  L SL FAY ++     L  
Sbjct: 238 LGVLSYGIFLGASSLFGYLFGRIRMKEFESLAF-LGYLIGALGSLGFAYLSSFGVFSLYP 296

Query: 308 AFVLYGLYMAIEDTIPRAYMADLAKEFEKGTVIGAYHTVFGVFVFPASIIVGYLWQTYSL 367
              L G  +A  +T     ++ + KE    T +G       + +F  ++I+G+L+Q  S 
Sbjct: 297 LSFLMGTSVASTETFEPTIISKITKEEAFSTSMGYLSAGRSIGIFLGNVIMGFLYQ-ISY 355

Query: 368 TVGFLYSAVMNVIAMIMMALLI 389
           T  +L++A+ ++I+  ++  LI
Sbjct: 356 TYAYLFAAITSLISFALILNLI 377


>gi|11498923 multidrug resistance protein [Archaeoglobus fulgidus]
           >gi|7483887|pir||D69415 multidrug resistance protein
           homolog - Archaeoglobus fulgidus
           >gi|2649251|gb|AAB89920.1| (AE001012) multidrug
           resistance protein [Archaeoglobus fulgidus]
           Length = 371
           
 Score = 81.1 bits (197), Expect = 2e-14
 Identities = 88/366 (24%), Positives = 159/366 (43%), Gaps = 25/366 (6%)

Query: 18  LVSFLNDMSSEMIAPIVPSYLTDILKIGKLASGSIMGLIESLSSLFKVLFGYISDKFRKR 77
           L  F    S   + PI+PSY +  L      S    G+     ++    FG +S+ + +R
Sbjct: 6   LSGFFAYASLSCVIPIIPSYASS-LGASVFLSAFAAGVFALFPAIAMTPFGMLSEVYGRR 64

Query: 78  KAFVALGYLISTISKGALAVTHSWWDFLIL-RILDRIGKGIRTAPRDALIAESSEKGKSG 136
           +  VA    ++++    L +  S  + L+  R L  +G  +     +AL+A+ SE+ + G
Sbjct: 65  RFLVAGA--VTSLLASLLYLQSSTAELLVFSRTLHGLGSALYIPSINALVADISEESRRG 122

Query: 137 KSFGFHRMMDTLGAVAGPLVAMGLLALLANYPKELAYRYIFLISAVPGVIGVLIVLLLVK 196
           ++ G  +    LG  AGPL A G ++             +F  +A+  V+GV       +
Sbjct: 123 EAMGKLQTALMLGFFAGPL-AGGFVSDFFGVKAVFLLALVFSAAALVPVVGV-----RER 176

Query: 197 DKGSEVKKKIKGISALKSSNLRIFLVIVAIAALGRYSYAFTLWKAEELGYSVFQGLGFYA 256
            KG E+ K+      L      +F+ +   ++L  ++  F    A EL  S  Q     A
Sbjct: 177 SKGGEIGKQFIFPRKLAPLFAVMFVGMATGSSLALFAIPF---YAPELNISQQQAGLLVA 233

Query: 257 LFNVIYALSAYPIGYYSDKVGKKIIITIGFGIAGLASLIFAYANNLPTLLLAFVLYGLYM 316
           +  +  A+   P G  +D+ G+ +   +G  + GL  L  A+  + P L LA +L G   
Sbjct: 234 VLFLFSAIIRVPAGILADRAGRNVTALLGMVVTGL-GLFSAFKPDFPFLFLASLLCGAGN 292

Query: 317 AIEDTIPRAYMADLAKEFEKGTVIGAYHTVFGVFVFPASIIVGYLWQTYSLTVGFL-YSA 375
            I +T   A  +D      +G  +G  +TV    +F  + + G++        GFL + +
Sbjct: 293 GIVNTAVFAAASDYE---NRGYAMGVANTVLNAGIFAGTTLAGFM-------AGFLSFQS 342

Query: 376 VMNVIA 381
           +M ++A
Sbjct: 343 MMLILA 348


>gb|AAK41264.1| Transport conserved hypothetical protein [Sulfolobus solfataricus]
           Length = 396
           
 Score = 78.8 bits (191), Expect = 1e-13
 Identities = 105/393 (26%), Positives = 163/393 (40%), Gaps = 32/393 (8%)

Query: 15  LLGLVSFLNDMSSEMIAPIVPSYLTDILKIGKLASGSIMG-LIESLSSLFKVLFGYISDK 73
           L  L  F+ND +S  + P+   +L   L I K   G + G     +S+L   L   I+DK
Sbjct: 8   LTSLSHFINDGNS-WVLPVTFIFLITYLGISKFLIGILSGAFFFGISALASPLVSKIADK 66

Query: 74  FRKRKAFVALGYL---ISTISKGALAVTHSWWDFLILRILDRIGKGIRTA---PRDALIA 127
           F    + + +G L   I  IS G     H    FL L  +     G  +A   P  A + 
Sbjct: 67  FTNYSSIMGIGILLWGIGLISFGYSIQLH----FLPLVFISVAIAGFASAFYHPIGAAVL 122

Query: 128 ESSEKGKSGKSFGFHRMMDTLGAVAGPLVAMGLLALLANYPKELAYRYIFLISAVPGVIG 187
             + KG +G + G +  M +LG    P + + L A+L N    L    I +IS +  +  
Sbjct: 123 SITYKGNAGIALGINGSMGSLGRAIYPTLTLSLFAIL-NKDMTLDMLIIGIISIIAALPS 181

Query: 188 VLIVLLLVKDKGSEVKKKIKGISALKSSNLRIFLVIVA----IAALGRYSYAFTLWKAEE 243
           + + + + K++  +        S   +  + I L I+A    I   G   +  TL   E 
Sbjct: 182 IFLKISITKEEDHKTPSSSNTTSTRGTLFVVILLTIIALLRSIFGQGISQFLPTLL-VEN 240

Query: 244 LGYSVFQGLGFYALFNVIYALSAYPI-GYYSDKVGKKIIITIGFGIAGLASLIFAYANNL 302
            GYS    LG      +  A+   PI G+ SD+VG+++I  I    A L  L+F    N+
Sbjct: 241 YGYSYNVNLGEAITIALAAAIVGQPILGFLSDRVGRRLIYAISTFGAALTLLLFLKIPNI 300

Query: 303 PTLLL----AFVLYGLYMAI-EDTIPRAYMADLAKEFEKGTVIGAYHTVFGVFVFPASII 357
             L L     F  + L ++I  D +PR      +  F    V G   T  GV      I+
Sbjct: 301 ALLSLFGFFNFSAFPLMLSIVGDFVPRN-----SASFANSLVWGLGVTGGGVI---GPIV 352

Query: 358 VGYLWQTYSLTVGFLYSAVMNVIAMIMMALLIK 390
           VG + Q  +L        +M  +A  + AL+ K
Sbjct: 353 VGAVSQVSNLVFASEIVTIMAFVAGALTALIPK 385


>gb|AAB31949.1| (S74031) NorA {ISP794, quinolone resistance} [Staphylococcus
           aureus, NCTC 8325, Peptide Insertion, 388 aa]
           Length = 388
           
 Score = 77.3 bits (187), Expect = 3e-13
 Identities = 86/405 (21%), Positives = 187/405 (45%), Gaps = 46/405 (11%)

Query: 4   RKVFGISWNVFLLGLVSFLNDMSSEMIAPIVPSYLTDILKIGKLASGSIMGLIESLSSLF 63
           +++F + +N+FL+ L          ++ P++P YL D+       +GS +GL+ +  +L 
Sbjct: 3   KQIFVLYFNIFLIFL-------GIGLVIPVLPVYLKDLG-----LTGSDLGLLVAAFALS 50

Query: 64  KVLF----GYISDKFRKRKAFVALGYLISTISKGALAVTHSWWDFLILRILDRIGKGIRT 119
           +++     G ++DK  K K  + +G ++ ++S+   AV H++   ++ R++  +  G+  
Sbjct: 51  QMIISPFGGTLADKLGK-KLIICIGLILFSVSEFMFAVGHNFSVLMLSRVIGGMSAGMVM 109

Query: 120 APRDALIAESSEKGKSGKSFGFHRMMDTLGAVAGPLVAMGLLALLANYPKELAYRYIFLI 179
                LIA+ S   +  K+FG+   +   G + GP +  G +A       E+++R  F  
Sbjct: 110 PGVTGLIADISPSHQKAKNFGYMSAIINSGFILGPGIG-GFMA-------EVSHRMPFYF 161

Query: 180 SAVPGVIGVLIVLLLVKDKGSEVKKKIKGI--SALKSSNLRIF-----LVIVAIAALGRY 232
           +   G++  ++ ++L+ D         + +    L   N ++F     L +V    L  +
Sbjct: 162 AGALGILAFIMSIVLIHDPKKSTTSGFQKLEPQLLTKINWKVFITPVILTLVLSFGLSAF 221

Query: 233 SYAFTLWKAEELGYS------VFQGLGFYALFNVIYALSAYPIGYYSDKVGKKIIITIGF 286
              ++L+ A+++ YS         G G +     IY    + + Y+S+     I  ++ +
Sbjct: 222 ETLYSLYTADKVNYSPKDISIAITGGGIFGALFQIYFFDKF-MKYFSELT--FIAWSLLY 278

Query: 287 GIAGLASLIFAYANNLPTLLLAFVLYGLYMAIEDTIPRAYMADLAKEFEKGTVIGAYHTV 346
            +  L  L+FA  +    +L++FV++  +  I   I   Y +++A E  +G   G   T 
Sbjct: 279 SVVVLILLVFA-NDYWSIMLISFVVFIGFDMIRPAITN-YFSNIAGE-RQGFAGGLNSTF 335

Query: 347 FGVFVFPASIIVGYLWQTYSLTVGFLYSAVMNVIAMIMMALLIKE 391
             +  F   +I G L+  +      +Y A+   +A +++ L+ K+
Sbjct: 336 TSMGNFIGPLIAGALFDVH--IEAPIYMAIGVSLAGVVIVLIEKQ 378


>sp|P21191|NORA_STAAU QUINOLONE RESISTANCE NORA PROTEIN >gi|97835|pir||A37838 norA
           protein - Staphylococcus aureus
           >gi|216975|dbj|BAA14147.1| (D90119) ORF for norA
           [Staphylococcus aureus]
           Length = 388
           
 Score = 76.9 bits (186), Expect = 4e-13
 Identities = 86/405 (21%), Positives = 186/405 (45%), Gaps = 46/405 (11%)

Query: 4   RKVFGISWNVFLLGLVSFLNDMSSEMIAPIVPSYLTDILKIGKLASGSIMGLIESLSSLF 63
           +++F + +N+FL+ L          ++ P++P YL D+       +GS +GL+ +  +L 
Sbjct: 3   KQIFVLYFNIFLIFL-------GIGLVIPVLPVYLKDLG-----LTGSDLGLLVAAFALS 50

Query: 64  KVLF----GYISDKFRKRKAFVALGYLISTISKGALAVTHSWWDFLILRILDRIGKGIRT 119
           +++     G ++DK  K K  + +G ++ ++S+   AV H++   ++ R++  +  G+  
Sbjct: 51  QMIISPFGGTLADKLGK-KLIICIGLILFSVSEFMFAVGHNFSVLMLSRVIGGMSAGMVM 109

Query: 120 APRDALIAESSEKGKSGKSFGFHRMMDTLGAVAGPLVAMGLLALLANYPKELAYRYIFLI 179
                LIA+ S   +  K+FG+   +   G + GP +  G +A       E+++R  F  
Sbjct: 110 PGVTGLIADISPSHQKAKNFGYMSAIINSGFILGPGIG-GFMA-------EVSHRMPFYF 161

Query: 180 SAVPGVIGVLIVLLLVKDKGSEVKKKIKGI--SALKSSNLRIF-----LVIVAIAALGRY 232
           +   G++  ++ ++L+ D         + +    L   N ++F     L +V    L  +
Sbjct: 162 AGALGILAFIMSIVLIHDPKKSTTSGFQKLEPQLLTKINWKVFITPVILTLVLSFGLSAF 221

Query: 233 SYAFTLWKAEELGYS------VFQGLGFYALFNVIYALSAYPIGYYSDKVGKKIIITIGF 286
              ++L+ A+++ YS         G G +     IY    + + Y+S+     I  ++ +
Sbjct: 222 ETLYSLYTADKVNYSPKDISIAITGGGIFGALFQIYFFDKF-MKYFSELT--FIAWSLLY 278

Query: 287 GIAGLASLIFAYANNLPTLLLAFVLYGLYMAIEDTIPRAYMADLAKEFEKGTVIGAYHTV 346
            +  L  L+FA       +L++FV++  +  I   I   Y +++A E  +G   G   T 
Sbjct: 279 SVVVLILLVFA-NGYWSIMLISFVVFIGFDMIRPAITN-YFSNIAGE-RQGFAGGLNSTF 335

Query: 347 FGVFVFPASIIVGYLWQTYSLTVGFLYSAVMNVIAMIMMALLIKE 391
             +  F   +I G L+  +      +Y A+   +A +++ L+ K+
Sbjct: 336 TSMGNFIGPLIAGALFDVH--IEAPIYMAIGVSLAGVVIVLIEKQ 378


>pir||D71112 hypothetical protein PH0667 - Pyrococcus horikoshii
           >gi|3257075|dbj|BAA29758.1| (AP000003) 413aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 413
           
 Score = 75.3 bits (182), Expect = 1e-12
 Identities = 93/377 (24%), Positives = 168/377 (43%), Gaps = 44/377 (11%)

Query: 37  YLTDILKI--GKLASGSIMGLIESLSS-LFKVLFGYISDKFRKRKAFVALGYLISTISKG 93
           YLT  +KI  G +    ++ +I +L+S +F+  FGY+SDK  KRK F+ LG L S  +  
Sbjct: 51  YLTVYMKIIGGTMFLVGLLSVIYNLTSAIFQYPFGYLSDKIGKRKPFIILGVLFSGTT-- 108

Query: 94  ALAVTHSWWDFLILRILDRIGK-GIRTAP-RDALIAESSEKGKSGKSFGFHRMMDTLGAV 151
            + V       L+L +    G  G   AP   ALI+E S   + G  FGF   ++ +G +
Sbjct: 109 YVLVIFISTPILLLSLRGTQGALGASFAPAHSALISELST--RVGSMFGFFNFVENMGFM 166

Query: 152 AGPLVAMGLLALLANYPKELAYRYIFLISAVPGVIGVLIVLLLVKDKGSEVKKKIKGI-- 209
            G  +   ++       K++  +  FL ++   ++ ++ +L L + K  E KKK  G   
Sbjct: 167 VGNFLGGYIV-------KKVGIKSAFLATS---IVSLVSILFLTQVKERERKKKNIGSFL 216

Query: 210 ----------SALKSSNLRIFL----------VIVAIAALGRYSYAFTLWKAEELGYSVF 249
                       +KSS  ++ +          V++A+ A G       ++  E+ G   F
Sbjct: 217 PIREGRESEKVEMKSSAFKMLMKGELGAFYLSVLLAMIASGEVYATVPVYFQEKFG-EEF 275

Query: 250 QGLGFYALFNVIYALSAYPIGYYSDKVGKKIIITIGFGIAGLASLIFAYANNLPTLLLAF 309
            G     + ++  AL +  IG   DK G+K+   +      L  + +A+A  +  + L  
Sbjct: 276 VGF-LLGIDSLAAALGSLLIGRLIDKYGEKVFYKLAILGYILTFIGYAWATTIIIMALVS 334

Query: 310 VLYGLYMAIEDTIPRAYMADLAKEFEKGTVIGAYHTVFGVFVFPASIIVGYLWQTYSLTV 369
           +L G+  A+  +    Y+A      E+G  +G  +T+  +      +I G +   +  +V
Sbjct: 335 LLSGVKWAMITSSASTYVARRVPHRERGQGMGLLNTMMTLGWVIGPLIGGLIADNFGFSV 394

Query: 370 GFLYSAVMNVIAMIMMA 386
             LYS  + +I   ++A
Sbjct: 395 -MLYSTTLPLIVSFLLA 410


>emb|CAC11594.1| (AL445064) sugar transport protein related protein [Thermoplasma
           acidophilum]
           Length = 486
           
 Score = 73.4 bits (177), Expect = 4e-12
 Identities = 80/371 (21%), Positives = 169/371 (44%), Gaps = 57/371 (15%)

Query: 68  GYISDKFRKRKAFVALGYLISTISKGALAVTHSWWDFLILRILDRIGKGIRTAPRDALIA 127
           G++SD+  +++ +      I+++     A++ S+++F I  +L  IG G       ++ A
Sbjct: 121 GHLSDRIGRKRMYT-YDLAITSVFLVLTALSTSFYEFFIFELLAGIGIGADYPLSSSIEA 179

Query: 128 ESSEKGKSGKSFGFHRMMDTLGAVAGPLVAMGLLALLANYPKELAYRYIFLISAVPGVIG 187
           E S +   G+   F+  M T+G++   ++++ L+    +     ++R+++ + A+  V+ 
Sbjct: 180 EFSPRRSRGRFLVFNIFMWTIGSIVFYVISIPLIFRFGSE----SWRWMYGVGAIVPVVV 235

Query: 188 VLI--------VLLLVKDKGSEVKKKI------------------KGISALKSSNLRIFL 221
           +L           L+   K SE K                     KG S+ +S     +L
Sbjct: 236 ILARRALPESPYWLVKAGKDSEAKTVADSMGREAGYTDVDLPNVEKGSSSFRSVFSGSYL 295

Query: 222 VIVAIAALGRYSYAFTLWKAEELGYSVFQGLGFYALFNVIYALSA---YPIGYYS----- 273
            ++  A+L  +SY  + +       S+F  +G  A+ +++  L       +G+       
Sbjct: 296 PLIIFASLAWFSYDVSSYGVWNYTPSIFVSVGVSAVSSILSTLLEDLPVIVGFIICLLLI 355

Query: 274 DKVGKKIIITIGFGIAGLASLIFA-YANN--LPTLLL--AFVLYGLYMAIEDT-IPRAYM 327
           ++VG+KI+ ++GFG+AG++ L FA YA++  LP ++L  AF +  L+  I  T +   Y 
Sbjct: 356 ERVGRKILQSVGFGLAGVSLLSFALYADHRTLPFIMLFTAFAMMHLFHNIGPTNLTYVYP 415

Query: 328 ADLAKEFEKGTVIG------AYHTVFGVFVFPASIIVGYLWQTYSLTVGFLYSAVMNVIA 381
            ++     +GT +G          + GVF FP       +  +  ++   ++ A+   + 
Sbjct: 416 VEIFPTRIRGTAMGIATAASRIGAILGVFAFP------LITASMGMSASLMFFAIFEFVG 469

Query: 382 MIMMALLIKES 392
            I+  +L  E+
Sbjct: 470 FIVTVVLAPET 480


>sp|P54559|YQJV_BACSU HYPOTHETICAL 44.7 KD PROTEIN IN GLNQ-ANSR INTERGENIC REGION
           >gi|7475632|pir||F69965 multidrug resistance protein
           homolog yqjV - Bacillus subtilis
           >gi|1303973|dbj|BAA12628.1| (D84432) YqjV [Bacillus
           subtilis] >gi|2634808|emb|CAB14305.1| (Z99116) similar
           to multidrug resistance protein [Bacillus subtilis]
           Length = 410
           
 Score = 71.0 bits (171), Expect = 2e-11
 Identities = 72/355 (20%), Positives = 150/355 (41%), Gaps = 28/355 (7%)

Query: 2   KERKVFGISWNVFLLGLVSFLNDMSSEMIAPIVPSYLTDILKIGKLASGSIMGLIESLSS 61
           K + +  ISW + ++G +     M++ M  P +  YLT +       +G ++    S+  
Sbjct: 3   KWKDIHPISWTI-IIGTI--FGRMATSMSIPFLAIYLTAVQGASASYAGLVIAASSSVGI 59

Query: 62  LFKVLFGYISDKF-RKRKAFVAL-GYLISTISKGALAVTHSWWDFLILRILDRIGKGIRT 119
           L     GYISDKF RK    V++ G+++        A   + W F ++  L+ + K +  
Sbjct: 60  LASFYGGYISDKFGRKNMMLVSIFGWMLVF---AGFAAASNLWVFFVVNALNGLCKSLFE 116

Query: 120 APRDALIAESSEKGKSGKSFGFHRMMDTLGAVAGPLVAMGLLALLANYPKELAYRYIFLI 179
               AL+++ +E+      F        +G V GP++ +   +  +  P        FL+
Sbjct: 117 PASKALLSDMTEEKTRLLVFNLRYAAINIGVVFGPVLGLYFGSSQSTTP--------FLV 168

Query: 180 SAV-PGVIGVLIVLLLVKDKGSEVKKKIKGIS-------ALKSSNLRIFLVIVAIAALGR 231
            AV  G+ G+++ L   K        + + +S         K     I LV + +   G 
Sbjct: 169 PAVIYGLYGIVLALQFKKHPSLSAPAQSRNMSVREAFMVTQKDYLFTIALVGITLCTFGY 228

Query: 232 YSYAFTLWKAEELGYSVFQGLGFYALFNVIYAL----SAYPIGYYSDKVGKKIIITIGFG 287
             ++ T  +       +  G   Y L   + A+    + +PI +++ +      + +G  
Sbjct: 229 SQFSSTFPQYMAQNPLIGNGTKLYGLMLTLNAIVVLATQFPIVHFAKRFSPLCSLMLGNV 288

Query: 288 IAGLASLIFAYANNLPTLLLAFVLYGLYMAIEDTIPRAYMADLAKEFEKGTVIGA 342
           +  ++  IF  ++ +P++++  + + +   +  ++   Y+  +AK   KGT  GA
Sbjct: 289 MVSISMAIFTVSHGVPSIVMIVITFTIGEVLLFSMMDLYVDQIAKPGLKGTYFGA 343


>pir||D71144 hypothetical protein PH0367 - Pyrococcus horikoshii
           >gi|3256758|dbj|BAA29441.1| (AP000002) 457aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 457
           
 Score = 70.2 bits (169), Expect = 4e-11
 Identities = 90/418 (21%), Positives = 184/418 (43%), Gaps = 58/418 (13%)

Query: 13  VFLLGLVSFLNDMSSEMIAPIVPSYLTDILK---IGKLASGSIMGLIESLSSLFKVLFGY 69
           + L+ + +FL  M+ + + P  P+Y   I+K   IG+   G +  +  + S+L  +++G 
Sbjct: 24  ILLVLMATFL--MADQNLLP--PNY-QQIMKEFGIGETQMGFVSSIFVATSALITIIWGM 78

Query: 70  ISDKFRKRKAFVALGYLISTISKGALAVTHSWWDFLILRILDRIGKGIRTAPRDALIAES 129
           ++D  ++RK  + +G L+  I     A  HS+W  L +R L  IG G       +LIA+ 
Sbjct: 79  LAD-IKQRKKLLVIGVLLGEIPCFLTAYVHSYWQLLTMRFLTGIGIGSIIPIGYSLIADM 137

Query: 130 SEKGKSGKSFGFHRMMDTLGAVAGPLVAMGLLALLANYPKELAYRYIFLISAVPG-VIGV 188
            E+ K G+ + +       G + G ++A G++          ++R  F+I+AVP  ++  
Sbjct: 138 FEEEKRGRGYSYIETAFGFGTLFGMIIA-GVIT---------SWRTPFIIAAVPNFILAP 187

Query: 189 LIVLLLVKDKGSEVKKKIK-------------GISALKSS-----NLRIFLV-IVAIAAL 229
           L  ++  + +  E +++I+              + A+K S     N+ IFL  I+     
Sbjct: 188 LFYIIAEEPRRGEGEREIRVLIEKGYEYAYKLSLEAVKKSLKTRTNILIFLQGIIGTVPW 247

Query: 230 GRYSYAFTLWKAEELGYSVFQGLGFYALFNVIYALSAYPIGYYSD-----KVGKKIIIT- 283
           G   Y    +     G           +  +   L +   G+  D     K G + +IT 
Sbjct: 248 GILMYWLISFLQVTRGMDKQTATFMLLIIGIASVLGSLFGGFVGDYFETRKRGGRAVITG 307

Query: 284 --IGFG-IAGLASLIFAYANNLPT-----LLLAFVLYGLYMAIEDTIPRAYMADLAKEFE 335
             I  G IA +  +++   + L T     L +  +L+  +++      RA ++ +    +
Sbjct: 308 IAIFLGMIAAIGLILYPLPSKLNTIHWLGLTVYSILFIQFVSYAGPNVRAIVSQVNLPED 367

Query: 336 KGTVIGAYHTVFGVFVFPASIIVGYLWQT-----YSLTVGFLYSAVMNVIAMIMMALL 388
           +GTV G ++ +  V      ++ G+L +T     Y+  + + Y+ ++  +  +  AL+
Sbjct: 368 RGTVFGLFNILDNVGKAIGPVLGGFLIETLVQMGYTKPLAYQYTLLIGTLFWVPCALV 425


>dbj|BAA36484.1| (AB019536) NorA [Staphylococcus aureus]
           Length = 388
           
 Score = 69.5 bits (167), Expect = 6e-11
 Identities = 82/405 (20%), Positives = 184/405 (45%), Gaps = 46/405 (11%)

Query: 4   RKVFGISWNVFLLGLVSFLNDMSSEMIAPIVPSYLTDILKIGKLASGSIMGLIESLSSLF 63
           +++F + +N+FL+ L          ++ P++P YL D+       +GS +GL+ +  +L 
Sbjct: 3   KQIFVLYFNIFLIFL-------GIGLVIPVLPVYLKDLG-----LTGSDLGLLVAAFALS 50

Query: 64  KVLF----GYISDKFRKRKAFVALGYLISTISKGALAVTHSWWDFLILRILDRIGKGIRT 119
           +++     G ++DK  K K  + +G ++ ++S+   AV H++   ++ R++  +  G+  
Sbjct: 51  QMIISPFGGTLADKLGK-KLIICIGLILFSVSEFMFAVGHNFSVLMLSRVIGGMSAGMVM 109

Query: 120 APRDALIAESSEKGKSGKSFGFHRMMDTLGAVAGPLVAMGLLALLANYPKELAYRYIFLI 179
                LIA+ S   +  K+FG+   +   G + GP +  G +A       E+++R  F  
Sbjct: 110 PGVTGLIADVSPSHQKAKNFGYMSAIINSGFILGPGIG-GFMA-------EVSHRMPFYF 161

Query: 180 SAVPGVIGVLIVLLLVKDKGSEVKKKIKGI--SALKSSNLRIF-----LVIVAIAALGRY 232
           +   G++  ++ ++L+ D         + +    L   N ++F     L +V    L  +
Sbjct: 162 AGALGILAFIMSVVLIHDPKKSTTSGFQKLEPQLLTKINWKVFITPAILTLVLAFGLSAF 221

Query: 233 SYAFTLWKAEELGYS------VFQGLGFYALFNVIYALSAYPIGYYSDKVGKKIIITIGF 286
              ++L+ + ++ YS         G G +     IY    + + Y+S+     I  ++ +
Sbjct: 222 ETLYSLYTSYKVNYSPKDISIAITGGGIFGALFQIYFFDKF-MKYFSELT--FIAWSLIY 278

Query: 287 GIAGLASLIFAYANNLPTLLLAFVLYGLYMAIEDTIPRAYMADLAKEFEKGTVIGAYHTV 346
            +  L  L+ A       ++++FV++  +  I   I   Y +++A +  +G   G   T 
Sbjct: 279 SVIVLVLLVIA-DGYWTIMVISFVVFIGFDMIRPAITN-YFSNIAGD-RQGFAGGLNSTF 335

Query: 347 FGVFVFPASIIVGYLWQTYSLTVGFLYSAVMNVIAMIMMALLIKE 391
             +  F   +I G L+  +      +Y A+   +A +++ L+ K+
Sbjct: 336 TSMGNFIGPLIAGALFDVH--IEAPIYMAIGVSLAGVVIVLIEKQ 378


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.327    0.143    0.412 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 130182903
Number of Sequences: 2977
Number of extensions: 5290987
Number of successful extensions: 18700
Number of sequences better than 1.0e-10: 25
Number of HSP's better than  0.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 18617
Number of HSP's gapped (non-prelim): 33
length of query: 392
length of database: 189,106,746
effective HSP length: 55
effective length of query: 337
effective length of database: 156,189,961
effective search space: 52636016857
effective search space used: 52636016857
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (21.7 bits)
S2: 166 (69.1 bits)