BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0881 (serS) DE:seryl-tRNA synthetase (serS)
(455 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||D75043 seryl-tRNA synthetase (sers) PAB0881 - Pyrococcus ab... 934 0.0
sp|O58441|SYS_PYRHO SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) ... 893 0.0
pir||G71117 serine--tRNA ligase (EC 6.1.1.11) - Pyrococcus horik... 893 0.0
gi|11499617 seryl-tRNA synthetase (serS) [Archaeoglobus fulgidus... 505 e-142
emb|CAB57698.1| (Y18930) seryl-trna synthetase [Sulfolobus solfa... 470 e-131
gb|AAK40914.1| Seryl-tRNA synthetase (serS) [Sulfolobus solfatar... 470 e-131
sp|Q9YAG3|SYS_AERPE SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) ... 452 e-126
emb|CAC11610.1| (AL445064) probable seryl-tRNA synthetase [Therm... 433 e-120
sp|Q9X199|SYS_THEMA SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) ... 398 e-110
sp|O66647|SYS_AQUAE SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) ... 379 e-104
sp|P37464|SYS_BACSU SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) ... 358 8e-98
sp|Q39230|SYS_ARATH SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) ... 344 1e-93
sp|P95689|SYS_STAAU SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) ... 344 1e-93
sp|O81983|SYS_HELAN SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) ... 341 8e-93
dbj|BAB03743.1| (AP001507) seryl-tRNA synthetase [Bacillus halod... 339 4e-92
sp|Q9ZBX1|SYS_STRCO SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) ... 332 4e-90
sp|O51244|SYS_BORBU SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) ... 330 2e-89
pir||G75414 seryl-tRNA synthetase - Deinococcus radiodurans (str... 327 2e-88
pir||T02786 serine--tRNA ligase (EC 6.1.1.11) - maize >gi|331977... 316 3e-85
sp|P96244|SYS_MYCTU SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) ... 316 3e-85
pir||T03949 serine--tRNA ligase (EC 6.1.1.11) serS - maize (frag... 314 1e-84
sp|P54221|SYS_HALMA SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) ... 312 5e-84
gb|AAG03084.1|AF297553_1 (AF297553) seryl-tRNA synthetase [Bos t... 307 1e-82
pir||G83320 seryl-tRNA synthetase PA2612 [imported] - Pseudomona... 305 5e-82
sp|O14018|SYSC_SCHPO SERYL-TRNA SYNTHETASE, CYTOPLASMIC (SERINE-... 302 6e-81
sp|P73201|SYS_SYNY3 SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) ... 301 1e-80
dbj|BAA95602.1| (D49914) Seryl tRNA Synthetase [Homo sapiens] 301 1e-80
gi|11428211 seryl-tRNA synthetase [Homo sapiens] 301 1e-80
gb|AAC17621.1| (AC002131) Similar to seryl-tRNA synthetase gb|U1... 301 1e-80
gi|5730029 seryl-tRNA synthetase [Homo sapiens] >gi|1351173|sp|P... 301 1e-80
gb|AAG02209.1|AF290915_1 (AF290915) seryl-tRNA synthetase [Candi... 299 5e-80
sp|O83653|SYS_TREPA SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) ... 298 7e-80
gi|6320226 seryl-tRNA synthetase; Ses1p [Saccharomyces cerevisia... 298 7e-80
emb|CAA28572.1| (X04884) seryl-tRNA synthetase [Saccharomyces ce... 297 2e-79
sp|P39919|SYS_COXBU SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) ... 291 1e-77
pir||D82932 seryl-tRNA synthetase UU106 [imported] - Ureaplasma ... 289 3e-77
gb|AAG20222.1| (AE005098) serine-tRNA synthetase; SerS [Halobact... 289 4e-77
pir||E81053 seryl-tRNA synthetase NMB1684 [imported] - Neisseria... 289 4e-77
sp|Q18678|SYS_CAEEL PROBABLE SERYL-TRNA SYNTHETASE (SERINE--TRNA... 288 1e-76
pir||E81822 serine--tRNA ligase (EC 6.1.1.11) NMA1943 [imported]... 287 2e-76
sp|P09156|SYS_ECOLI SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) ... 279 4e-74
sp|Q9Z736|SYS_CHLPN SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) ... 279 5e-74
gb|AAF51155.1| (AE003581) CG17259 gene product [Drosophila melan... 279 5e-74
pdb|1SES|A Chain A, Seryl-Trna Synthetase (E.C.6.1.1.11) (Serine... 278 1e-73
sp|P34945|SYS_THETH SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) ... 276 4e-73
pir||C81382 serine--tRNA ligase (EC 6.1.1.11) Cj0389 [imported] ... 273 4e-72
sp|P56458|SYS_HELPY SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) ... 272 6e-72
sp|Q9ZJD9|SYS_HELPJ SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) ... 270 2e-71
sp|O84734|SYS_CHLTR SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) ... 269 4e-71
pir||A82242 seryl-tRNA synthetase VC1110 [imported] - Vibrio cho... 268 7e-71
pir||C81742 seryl-tRNA synthetase TC0102 [imported] - Chlamydia ... 266 4e-70
sp|Q9ZCG5|SYS_RICPR SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) ... 262 5e-69
sp|P81434|SYS_BUCAP SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) ... 260 3e-68
sp|P43833|SYS_HAEIN SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) ... 259 4e-68
sp|P57398|SYS_BUCAI SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) ... 258 8e-68
pir||E82577 seryl-tRNA synthetase XF2286 [imported] - Xylella fa... 257 2e-67
sp|P47251|SYS_MYCGE SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) ... 256 3e-67
sp|P75107|SYS_MYCPN SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) ... 251 1e-65
gi|6321799 Seryl-tRNA synthetase; Dia4p [Saccharomyces cerevisia... 239 4e-62
pir||T50193 probable seryl-trna synthetase [imported] - fission ... 225 7e-58
dbj|BAA99558.1| (AB029949) mitochondrial seryl-tRNA synthetase [... 223 3e-57
dbj|BAA99556.1| (AB029947) mitochondrial seryl-tRNA synthetase [... 221 1e-56
gi|8923421 hypothetical protein FLJ20450 [Homo sapiens] >gi|1143... 217 2e-55
gb|AAF55175.1| (AE003708) Aats-ser gene product [Drosophila mela... 184 2e-45
emb|CAA75101.1| (Y14823) seryl-tRNA synthetase [Drosophila melan... 180 2e-44
gb|AAA83842.1| (J03412) ORF X; putative [Escherichia coli] 180 4e-44
sp|P26636|SYS_CRIGR SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) ... 173 4e-42
pir||T34480 hypothetical protein W03B1.4 - Caenorhabditis elegan... 169 4e-41
pir||T37315 serine--tRNA ligase (EC 6.1.1.11) - Caenorhabditis e... 169 4e-41
sp|P26638|SYS_MOUSE SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) ... 94 2e-18
pir||A41019 serine--tRNA ligase (EC 6.1.1.11) - mouse (fragment) 93 7e-18
sp|O33780|SYS_SULSO SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) ... 73 9e-12
>pir||D75043 seryl-tRNA synthetase (sers) PAB0881 - Pyrococcus abyssi (strain
Orsay) >gi|5458754|emb|CAB50241.1| (AJ248287) seryl-tRNA
synthetase (serS) [Pyrococcus abyssi]
Length = 455
Score = 934 bits (2388), Expect = 0.0
Identities = 455/455 (100%), Positives = 455/455 (100%)
Query: 1 MLDIKLIRENPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIE 60
MLDIKLIRENPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIE
Sbjct: 1 MLDIKLIRENPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIE 60
Query: 61 IGKRRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGESE 120
IGKRRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGESE
Sbjct: 61 IGKRRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGESE 120
Query: 121 EDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARAAKV 180
EDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARAAKV
Sbjct: 121 EDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARAAKV 180
Query: 181 SGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEGSTTFEDFEDVIY 240
SGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEGSTTFEDFEDVIY
Sbjct: 181 SGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEGSTTFEDFEDVIY 240
Query: 241 KVEGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKGIFRVH 300
KVEGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKGIFRVH
Sbjct: 241 KVEGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKGIFRVH 300
Query: 301 QFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKYDIEA 360
QFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKYDIEA
Sbjct: 301 QFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKYDIEA 360
Query: 361 WMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIVAILEN 420
WMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIVAILEN
Sbjct: 361 WMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIVAILEN 420
Query: 421 HQEEDGTVKIPKVLWKYTGFKEIVPVEKKERCCSS 455
HQEEDGTVKIPKVLWKYTGFKEIVPVEKKERCCSS
Sbjct: 421 HQEEDGTVKIPKVLWKYTGFKEIVPVEKKERCCSS 455
>sp|O58441|SYS_PYRHO SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) (SERRS)
Length = 455
Score = 893 bits (2282), Expect = 0.0
Identities = 425/455 (93%), Positives = 445/455 (97%)
Query: 1 MLDIKLIRENPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIE 60
MLDIKLIRENPELVKNDL KRGELEK+KW+DEILKLD EWR KLKEIN+LRHERNKIA+E
Sbjct: 1 MLDIKLIRENPELVKNDLIKRGELEKVKWVDEILKLDTEWRTKLKEINRLRHERNKIAVE 60
Query: 61 IGKRRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGESE 120
IGKRRKKGEPV+ELLAKS+EIVKRI LE EVEELKKKIDYYLWRLPNITHPSVP+G+ E
Sbjct: 61 IGKRRKKGEPVDELLAKSREIVKRIGELENEVEELKKKIDYYLWRLPNITHPSVPVGKDE 120
Query: 121 EDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARAAKV 180
DNVPIRFWGKARVW+GHLERFLEQSQGKMEYE+LEW+PKLHVDLLEILGGADFARAAKV
Sbjct: 121 NDNVPIRFWGKARVWKGHLERFLEQSQGKMEYEILEWKPKLHVDLLEILGGADFARAAKV 180
Query: 181 SGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEGSTTFEDFEDVIY 240
SGSRFYYLLNEIVILDLALIRFALD LI+KGFTPVIPPYMVRRFVEEGST+FEDFEDVIY
Sbjct: 181 SGSRFYYLLNEIVILDLALIRFALDRLIEKGFTPVIPPYMVRRFVEEGSTSFEDFEDVIY 240
Query: 241 KVEGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKGIFRVH 300
KVE EDLYLIPTAEHPLAGMHANEILDGKDLPLLYVG+SPCFRKEAGTAGKDTKGIFRVH
Sbjct: 241 KVEDEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGVSPCFRKEAGTAGKDTKGIFRVH 300
Query: 301 QFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKYDIEA 360
QFHKVEQFVYSRPEESWEWHE+IIRNAEELFQ+LEIPYRVVNICTGDLGYVAAKKYDIEA
Sbjct: 301 QFHKVEQFVYSRPEESWEWHEKIIRNAEELFQELEIPYRVVNICTGDLGYVAAKKYDIEA 360
Query: 361 WMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIVAILEN 420
WMPGQG+FREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIVAILEN
Sbjct: 361 WMPGQGKFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIVAILEN 420
Query: 421 HQEEDGTVKIPKVLWKYTGFKEIVPVEKKERCCSS 455
HQEEDGTV+IPKVLWKYTGFKEIVPVEKKERCC++
Sbjct: 421 HQEEDGTVRIPKVLWKYTGFKEIVPVEKKERCCAT 455
>pir||G71117 serine--tRNA ligase (EC 6.1.1.11) - Pyrococcus horikoshii
>gi|3257118|dbj|BAA29801.1| (AP000003) 460aa long
hypothetical seryl-tRNA synthetase [Pyrococcus
horikoshii]
Length = 460
Score = 893 bits (2282), Expect = 0.0
Identities = 425/455 (93%), Positives = 445/455 (97%)
Query: 1 MLDIKLIRENPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIE 60
MLDIKLIRENPELVKNDL KRGELEK+KW+DEILKLD EWR KLKEIN+LRHERNKIA+E
Sbjct: 6 MLDIKLIRENPELVKNDLIKRGELEKVKWVDEILKLDTEWRTKLKEINRLRHERNKIAVE 65
Query: 61 IGKRRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGESE 120
IGKRRKKGEPV+ELLAKS+EIVKRI LE EVEELKKKIDYYLWRLPNITHPSVP+G+ E
Sbjct: 66 IGKRRKKGEPVDELLAKSREIVKRIGELENEVEELKKKIDYYLWRLPNITHPSVPVGKDE 125
Query: 121 EDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARAAKV 180
DNVPIRFWGKARVW+GHLERFLEQSQGKMEYE+LEW+PKLHVDLLEILGGADFARAAKV
Sbjct: 126 NDNVPIRFWGKARVWKGHLERFLEQSQGKMEYEILEWKPKLHVDLLEILGGADFARAAKV 185
Query: 181 SGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEGSTTFEDFEDVIY 240
SGSRFYYLLNEIVILDLALIRFALD LI+KGFTPVIPPYMVRRFVEEGST+FEDFEDVIY
Sbjct: 186 SGSRFYYLLNEIVILDLALIRFALDRLIEKGFTPVIPPYMVRRFVEEGSTSFEDFEDVIY 245
Query: 241 KVEGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKGIFRVH 300
KVE EDLYLIPTAEHPLAGMHANEILDGKDLPLLYVG+SPCFRKEAGTAGKDTKGIFRVH
Sbjct: 246 KVEDEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGVSPCFRKEAGTAGKDTKGIFRVH 305
Query: 301 QFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKYDIEA 360
QFHKVEQFVYSRPEESWEWHE+IIRNAEELFQ+LEIPYRVVNICTGDLGYVAAKKYDIEA
Sbjct: 306 QFHKVEQFVYSRPEESWEWHEKIIRNAEELFQELEIPYRVVNICTGDLGYVAAKKYDIEA 365
Query: 361 WMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIVAILEN 420
WMPGQG+FREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIVAILEN
Sbjct: 366 WMPGQGKFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIVAILEN 425
Query: 421 HQEEDGTVKIPKVLWKYTGFKEIVPVEKKERCCSS 455
HQEEDGTV+IPKVLWKYTGFKEIVPVEKKERCC++
Sbjct: 426 HQEEDGTVRIPKVLWKYTGFKEIVPVEKKERCCAT 460
>gi|11499617 seryl-tRNA synthetase (serS) [Archaeoglobus fulgidus]
>gi|3334361|sp|O28244|SYS_ARCFU SERYL-TRNA SYNTHETASE
(SERINE--TRNA LIGASE) (SERRS) >gi|7437679|pir||B69504
seryl-tRNA synthetase (serS) homolog - Archaeoglobus
fulgidus >gi|2648500|gb|AAB89219.1| (AE000962)
seryl-tRNA synthetase (serS) [Archaeoglobus fulgidus]
Length = 453
Score = 505 bits (1286), Expect = e-142
Identities = 242/435 (55%), Positives = 326/435 (74%), Gaps = 5/435 (1%)
Query: 4 IKLIRENPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIEIGK 63
+K +RENPE++ ++RG I +D ++LD +WR +LK +N+LR RN++A +
Sbjct: 5 LKAVRENPEILYESQRRRGLSVDI--VDRAIELDRKWREELKRVNQLRKRRNELARAV-- 60
Query: 64 RRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGESEEDN 123
+ KGE +++ ++K + + ++ E+E++ L+ +++ L +PNI H SVP+G+ + +N
Sbjct: 61 KEAKGEERAKVIEEAKAVSEEVKRAEEELKRLEAELEEVLLSIPNIIHESVPVGKDDSEN 120
Query: 124 VPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARAAKVSGS 183
VPI++WGKA+V+ ++ F+E +QG EYEV + +P H D +EI G AD RAAKV+G+
Sbjct: 121 VPIKYWGKAKVYFEDVDAFVEMTQGMAEYEVTDVKPIGHADAVEIFGWADLERAAKVAGA 180
Query: 184 RFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEGSTTFEDFEDVIYKVE 243
RFYYLLN++V LD AL +ALD L K+ FT V PPYM+RR G T F DFE+VIYKVE
Sbjct: 181 RFYYLLNDLVWLDFALTMYALDFLRKEDFTIVSPPYMMRREAYSGVTAFSDFEEVIYKVE 240
Query: 244 GEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKGIFRVHQFH 303
EDLYLI T+EHP+A MH E+L+ ++LPLLY G+SPCFRKEAG GKDTKGIFRVHQF+
Sbjct: 241 DEDLYLIATSEHPIAAMHMREVLEERELPLLYAGVSPCFRKEAGAHGKDTKGIFRVHQFN 300
Query: 304 KVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKYDIEAWMP 363
KVEQFV+ PE+SWEWHE++I N E+L+Q L IPYR+VNICTGDLG VAAKKYD+EAWMP
Sbjct: 301 KVEQFVFCLPEQSWEWHEKLIENVEKLWQGLGIPYRIVNICTGDLGIVAAKKYDLEAWMP 360
Query: 364 GQGRFREVVSASNCTDWQARRLNIRF-RDRTDEKPRYVHTLNSTAIATSRAIVAILENHQ 422
Q ++RE+VS SNCTDWQ+ RL+IRF +R +VHTLNSTAIAT+RAI AI+EN Q
Sbjct: 361 AQAKYREMVSCSNCTDWQSYRLDIRFAEERGKPSKGFVHTLNSTAIATTRAITAIIENFQ 420
Query: 423 EEDGTVKIPKVLWKY 437
EDG V+IP+VL KY
Sbjct: 421 LEDGRVEIPRVLRKY 435
>emb|CAB57698.1| (Y18930) seryl-trna synthetase [Sulfolobus solfataricus]
Length = 457
Score = 470 bits (1197), Expect = e-131
Identities = 226/436 (51%), Positives = 318/436 (72%), Gaps = 6/436 (1%)
Query: 4 IKLIRENPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIEIGK 63
++L+R+NPE +KN+LK+R + +D+ ++LD +WR L+E+ KLRH+ N ++ +I K
Sbjct: 6 LELLRKNPEDLKNNLKRRAI--DVSLVDKAVELDKKWRQVLQEVEKLRHQHNVLSSQISK 63
Query: 64 RRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGESEEDN 123
GE ++ + +SK ++K +E EKE+EE++ + D L LPN+ VP G + N
Sbjct: 64 L--SGEERKKKIEESKNLLKILEEKEKELEEIENERDRLLSSLPNLVADDVPNGPDDSYN 121
Query: 124 VPIRFWGKARVWEGHLERFLEQ-SQGKMEYEVLEWRPKLHVDLLE-ILGGADFARAAKVS 181
VPI+FWGK +V+EG ++ FL+Q K+ YEV++W+PK H ++LE +L + +AA+++
Sbjct: 122 VPIKFWGKFKVYEGDVQEFLKQIKDAKVNYEVIKWKPKGHAEMLEDVLHLGNTLKAAEIA 181
Query: 182 GSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEGSTTFEDFEDVIYK 241
GSRFYYL N+IV LD +L+ FA+D + ++G+T V+PPYM+R V + + F+D IYK
Sbjct: 182 GSRFYYLFNDIVWLDFSLLLFAIDYITQQGYTLVLPPYMLRGEVIQSVIDLDTFKDAIYK 241
Query: 242 VEGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKGIFRVHQ 301
+E EDLYLI TAEHP+A M E ++ LPL + GISP FRKEA A KD KGIFRVHQ
Sbjct: 242 IENEDLYLIATAEHPIAAMFFKEEIEKDKLPLKFAGISPAFRKEASAANKDLKGIFRVHQ 301
Query: 302 FHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKYDIEAW 361
FHKVEQF++S PE+SW++H +I NAE +FQ+LE+PYR+VNI +GDLG AAKK+D+E W
Sbjct: 302 FHKVEQFIFSTPEDSWKYHSELITNAESIFQQLELPYRIVNIASGDLGACAAKKFDLEVW 361
Query: 362 MPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIVAILENH 421
MP Q +FRE+VS SNCTDWQA R+ IR+ DR + + YVHTLNSTAIA++R I AILEN+
Sbjct: 362 MPAQAKFREMVSCSNCTDWQAFRMKIRYVDRKNNRRGYVHTLNSTAIASTRTITAILENY 421
Query: 422 QEEDGTVKIPKVLWKY 437
Q EDG V++PKVL KY
Sbjct: 422 QREDGVVEVPKVLRKY 437
>gb|AAK40914.1| Seryl-tRNA synthetase (serS) [Sulfolobus solfataricus]
Length = 457
Score = 470 bits (1197), Expect = e-131
Identities = 226/436 (51%), Positives = 318/436 (72%), Gaps = 6/436 (1%)
Query: 4 IKLIRENPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIEIGK 63
++L+R+NPE +KN+LK+R + +D+ ++LD +WR L+E+ KLRH+ N ++ +I K
Sbjct: 6 LELLRKNPEDLKNNLKRRAI--DVSLVDKAVELDKKWRQVLQEVEKLRHQHNVLSSQISK 63
Query: 64 RRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGESEEDN 123
GE ++ + +SK ++K +E EKE+EE++ + D L LPN+ VP G + N
Sbjct: 64 L--SGEERKKKIEESKNLLKILEEKEKELEEIENERDRLLSSLPNLVADDVPNGPDDSYN 121
Query: 124 VPIRFWGKARVWEGHLERFLEQ-SQGKMEYEVLEWRPKLHVDLLE-ILGGADFARAAKVS 181
VPI+FWGK +V+EG ++ FL+Q K+ YEV++W+PK H ++LE +L + +AA+++
Sbjct: 122 VPIKFWGKFKVYEGDVQEFLKQIKDAKVNYEVIKWKPKGHAEMLEDVLHLGNTLKAAEIA 181
Query: 182 GSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEGSTTFEDFEDVIYK 241
GSRFYYL N+IV LD +L+ FA+D + ++G+T V+PPYM+R V + + F+D IYK
Sbjct: 182 GSRFYYLFNDIVWLDFSLLLFAIDYITQQGYTLVLPPYMLRGEVIQSVIDLDTFKDAIYK 241
Query: 242 VEGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKGIFRVHQ 301
+E EDLYLI TAEHP+A M E ++ LPL + GISP FRKEA A KD KGIFRVHQ
Sbjct: 242 IENEDLYLIATAEHPIAAMFFKEEIEKDKLPLKFAGISPAFRKEASAANKDLKGIFRVHQ 301
Query: 302 FHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKYDIEAW 361
FHKVEQF++S PE+SW++H +I NAE +FQ+LE+PYR+VNI +GDLG AAKK+D+E W
Sbjct: 302 FHKVEQFIFSTPEDSWKYHSELITNAESIFQQLELPYRIVNIASGDLGACAAKKFDLEVW 361
Query: 362 MPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIVAILENH 421
MP Q +FRE+VS SNCTDWQA R+ IR+ DR + + YVHTLNSTAIA++R I AILEN+
Sbjct: 362 MPAQAKFREMVSCSNCTDWQAFRMKIRYVDRKNNRRGYVHTLNSTAIASTRTITAILENY 421
Query: 422 QEEDGTVKIPKVLWKY 437
Q EDG V++PKVL KY
Sbjct: 422 QREDGVVEVPKVLRKY 437
>sp|Q9YAG3|SYS_AERPE SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) (SERRS)
>gi|7437682|pir||B72500 probable seryl-tRNA synthetase
APE1976 - Aeropyrum pernix (strain K1)
>gi|5105674|dbj|BAA80986.1| (AP000063) 463aa long
hypothetical seryl-tRNA synthetase [Aeropyrum pernix]
Length = 463
Score = 452 bits (1150), Expect = e-126
Identities = 225/438 (51%), Positives = 310/438 (70%), Gaps = 8/438 (1%)
Query: 4 IKLIRENPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIEIGK 63
++L+R NPE +K ++KR L +D +LD EWR L +N++R N+I I K
Sbjct: 10 LELLRSNPEALKEHVRKR--LMDPAIVDRAYRLDVEWRRLLTMVNEVRRRHNEITRMIAK 67
Query: 64 RRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGESEEDN 123
+ E E L+A++K +++ E LE+++++++++ + L LPNI P VP+G+ E
Sbjct: 68 AGSREER-ERLIAEAKRLLREREDLEEKLKKVEREREEALLGLPNIVAPDVPVGD-ESAT 125
Query: 124 VPIRFWGKARVWEGHLERFLEQSQG---KMEYEVLEWRPKLHVDLLE-ILGGADFARAAK 179
PI FWGK +VW+GH++ F EQ++ K+++EV+EWRP+ H D++E +L D RAA+
Sbjct: 126 RPIEFWGKPKVWKGHVDAFREQTEAYGFKVDHEVIEWRPRGHADMMEEVLKLGDTLRAAR 185
Query: 180 VSGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEGSTTFEDFEDVI 239
V+GSRFYYL ++V LDLAL+ +A+D + KG+ V+PPYM+R V E F+D I
Sbjct: 186 VAGSRFYYLFEDLVFLDLALLMYAIDFMTSKGYVLVLPPYMLRYNVMSRVIDLETFKDAI 245
Query: 240 YKVEGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKGIFRV 299
Y++ GEDLYLI TAEHPLA ++ N + +DLPL VG+SPCFRKEAG +D KGIFRV
Sbjct: 246 YEIAGEDLYLIATAEHPLAALYYNSEIYDEDLPLKLVGVSPCFRKEAGAGNRDLKGIFRV 305
Query: 300 HQFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKYDIE 359
HQFHKVEQFVYS PEES + HE +I NA+E+F+ LEIP+RVVNI +GDLG A KKYD+E
Sbjct: 306 HQFHKVEQFVYSLPEESSKLHEELISNAKEIFKGLEIPFRVVNIASGDLGACAVKKYDLE 365
Query: 360 AWMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIVAILE 419
AWMP QG++RE+VSASNCTDWQA RL IR R + YVHTLN+TA+A++R I AILE
Sbjct: 366 AWMPAQGKYREMVSASNCTDWQAYRLGIRLVRRKGMERGYVHTLNATAVASTRTITAILE 425
Query: 420 NHQEEDGTVKIPKVLWKY 437
N Q+E+G V IP+ L +Y
Sbjct: 426 NFQDEEGVVAIPRALRRY 443
>emb|CAC11610.1| (AL445064) probable seryl-tRNA synthetase [Thermoplasma
acidophilum]
Length = 441
Score = 433 bits (1101), Expect = e-120
Identities = 218/443 (49%), Positives = 312/443 (70%), Gaps = 5/443 (1%)
Query: 1 MLDIKLIRENPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIE 60
M+D+KL+R N EL + + + RG ++K +++ +LD EWR+ +E+N LR ++N+ +
Sbjct: 1 MIDVKLLRSNRELFEKNCEYRG-VDKAP-VEDFFRLDEEWRSINRELNGLRSQKNRETRK 58
Query: 61 IGKRRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGESE 120
I + K ++I RI LE ++++++++ D LW +PN+ H SVP+ +
Sbjct: 59 IAELIKNNGDASAEKKAVEDINARISDLENKLKKIEEERDRILWTIPNLVHESVPVCFGD 118
Query: 121 EDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARAAKV 180
E+N +R+ G A+V+ +E F + S +YEVL+ RPK HVDL L D AA++
Sbjct: 119 ENNQLVRYVGHAKVFRDDIEEFKKNSGNSQDYEVLDERPKSHVDLGLDLNVIDLESAARI 178
Query: 181 SGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEGSTTFEDFEDVIY 240
SGSRFY++ N ++ L++AL +A+D L ++GF+ V PPYM+ G+T E F+D +Y
Sbjct: 179 SGSRFYFIKNRLLKLEMALENYAVDFLSQRGFSIVEPPYMLNLESMRGATDLETFKDTLY 238
Query: 241 KVEGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKGIFRVH 300
K+EGEDLYLI T+EH +A M +N+ L+ KDLPL GIS CFR+EAG GKDTKGIFRVH
Sbjct: 239 KIEGEDLYLIATSEHSIAAMLSNQFLEEKDLPLRVAGISACFRREAGAHGKDTKGIFRVH 298
Query: 301 QFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKYDIEA 360
QF+K+EQFV+ +PE+SW++ E I+ NAE +++ L IPYRVVN+C+G+LG +AAKKYDIEA
Sbjct: 299 QFNKIEQFVFCKPEDSWDFLEEILGNAEAIYRSLGIPYRVVNVCSGELGRLAAKKYDIEA 358
Query: 361 WMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIVAILEN 420
W P QG+FRE+VSASN TD+QAR LNI++ RT E R+VHTLNSTAIAT+R +VAI+EN
Sbjct: 359 WFPAQGKFREIVSASNDTDYQARSLNIKY--RTSEGNRFVHTLNSTAIATTRILVAIMEN 416
Query: 421 HQEEDGTVKIPKVLWKYTGFKEI 443
QE D ++IP VL YTGF+ I
Sbjct: 417 FQEGD-RIRIPDVLVPYTGFQYI 438
>sp|Q9X199|SYS_THEMA SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) (SERRS)
>gi|7437675|pir||D72261 serine--tRNA ligase (EC
6.1.1.11) - Thermotoga maritima (strain MSB8)
>gi|4981940|gb|AAD36449.1|AE001791_11 (AE001791)
seryl-tRNA synthetase [Thermotoga maritima]
Length = 425
Score = 398 bits (1011), Expect = e-110
Identities = 207/448 (46%), Positives = 300/448 (66%), Gaps = 26/448 (5%)
Query: 1 MLDIKLIRENPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIE 60
M+DIKLIR+NP+ VK L+KRGE I IDEILK+DA+WRA + + N+LR RN+I+
Sbjct: 1 MIDIKLIRQNPDFVKEALRKRGEDPAI--IDEILKIDADWRATITKTNELRSRRNEISKN 58
Query: 61 IGKRRKKGE--PVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGE 118
+ + +K+G+ E L+ + K + + I++LE++ +EL+KK++ L +PNI H SVP+GE
Sbjct: 59 VARLKKEGKNAEAEALIEEGKRLGEEIKALEEKEKELQKKLNDLLLMIPNIPHESVPVGE 118
Query: 119 SEEDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARAA 178
E NV +R WG+ R ++ + P H DL G DF+RA+
Sbjct: 119 DESQNVEVRRWGEPREFD--------------------FTPLAHWDLGPAWGLMDFSRAS 158
Query: 179 KVSGSRFYYLLNEIVILDLALIRFALDELIKK-GFTPVIPPYMVRRFVEEGSTTFEDFED 237
K+SGSRF + ++ L+ ALI F LD K+ G+T V P++V+R + FE+
Sbjct: 159 KLSGSRFTVMYGKLARLERALINFMLDVHTKEHGYTEVWVPHLVKRETITITGQLPKFEE 218
Query: 238 VIYKVEGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKGIF 297
+Y E +DL+LIPTAE PLA +H+ EIL+ K+LP YV +PC+R+EAG+ GKD +G+
Sbjct: 219 ELYLAERDDLFLIPTAEVPLAALHSGEILEEKELPKKYVSYTPCYRREAGSYGKDVRGMI 278
Query: 298 RVHQFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKYD 357
R HQF KVE + PE S+E E ++++AE + +KLE+PYRVV++CTGDLG+ +AK YD
Sbjct: 279 RQHQFDKVELVWVTTPERSFEDLEELVKDAETILRKLELPYRVVSLCTGDLGFTSAKTYD 338
Query: 358 IEAWMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIVAI 417
IE W+P ++E+ S SN TD+QARR N+R+R R+D K YVHTLN + IA RA+VAI
Sbjct: 339 IEVWLPSYNAYKEISSCSNVTDFQARRGNMRYRRRSDGKLEYVHTLNGSGIAVGRALVAI 398
Query: 418 LENHQEEDGTVKIPKVLWKYTGFKEIVP 445
LEN+Q+ DG+V++P+VL YTGF E++P
Sbjct: 399 LENYQQPDGSVRVPEVLVPYTGF-EVIP 425
>sp|O66647|SYS_AQUAE SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) (SERRS)
>gi|7437674|pir||C70327 serine--tRNA ligase (EC
6.1.1.11) - Aquifex aeolicus >gi|2982982|gb|AAC06595.1|
(AE000682) seryl-tRNA synthetase [Aquifex aeolicus]
Length = 425
Score = 379 bits (964), Expect = e-104
Identities = 195/445 (43%), Positives = 284/445 (63%), Gaps = 21/445 (4%)
Query: 1 MLDIKLIRENPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIE 60
M+DI LIRE P+ VK L R + E + +D++L+LD R +K + LR ERNK++ E
Sbjct: 1 MIDINLIREKPDYVKERLATRDK-ELVSLVDKVLELDKRRREIIKRLEALRSERNKLSKE 59
Query: 61 IGKRRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGESE 120
IGK +++G+ E+ + KE+ + I+ LE+E+ ++++++ L +PN+ HPSVP+GE E
Sbjct: 60 IGKLKREGKDTTEIQNRVKELKEEIDRLEEELRKVEEELKNTLLWIPNLPHPSVPVGEDE 119
Query: 121 EDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARAAKV 180
+DNV +R WG+ R K ++E PK H ++ E LG DF R AK+
Sbjct: 120 KDNVEVRRWGEPR---------------KFDFE-----PKPHWEIGERLGILDFKRGAKL 159
Query: 181 SGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEGSTTFEDFEDVIY 240
SGSRF + L+ ALI F LD KKG+ + PP++V+ + G+ FE+ +Y
Sbjct: 160 SGSRFTVIAGWGARLERALINFMLDLHTKKGYKEICPPHLVKPEILIGTGQLPKFEEDLY 219
Query: 241 KVEGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKGIFRVH 300
K E ++LYLIPTAE PL ++ EIL ++LP+ +PC+R+EAG GKD +GI R H
Sbjct: 220 KCERDNLYLIPTAEVPLTNLYREEILKEENLPIYLTAYTPCYRREAGAYGKDIRGIIRQH 279
Query: 301 QFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKYDIEA 360
QF KVE P+ S++ E+++++AEE+ Q L +PYRVV +CTGDLG+ AAK YDIE
Sbjct: 280 QFDKVELVKIVHPDTSYDELEKLVKDAEEVLQLLGLPYRVVELCTGDLGFSAAKTYDIEV 339
Query: 361 WMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIVAILEN 420
W P Q ++RE+ S SNC D+QARR+N RF+D K R+VHTLN + +A R + AILEN
Sbjct: 340 WFPSQNKYREISSCSNCEDFQARRMNTRFKDSKTGKNRFVHTLNGSGLAVGRTLAAILEN 399
Query: 421 HQEEDGTVKIPKVLWKYTGFKEIVP 445
+Q+EDG+V +P+VL Y G I P
Sbjct: 400 YQQEDGSVVVPEVLRDYVGTDVIRP 424
>sp|P37464|SYS_BACSU SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) (SERRS)
>gi|2127203|pir||S66043 serine--tRNA ligase (EC
6.1.1.11) - Bacillus subtilis >gi|467403|dbj|BAA05249.1|
(D26185) seryl-tRNA synthetase [Bacillus subtilis]
>gi|2632280|emb|CAB11789.1| (Z99104) seryl-tRNA
synthetase [Bacillus subtilis]
Length = 425
Score = 358 bits (909), Expect = 8e-98
Identities = 185/445 (41%), Positives = 275/445 (61%), Gaps = 23/445 (5%)
Query: 1 MLDIKLIRENPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIE 60
MLD K++R N + +K L +GE + D+ LD R + ++ +L+ +RN+++ +
Sbjct: 1 MLDTKMLRANFQEIKAKLVHKGE--DLTDFDKFEALDDRRRELIGKVEELKGKRNEVSQQ 58
Query: 61 IGKRRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGESE 120
+ +++ + + ++ + +E+ + I+ L++E+ ++ ++D L +PNI H SVP+GE+E
Sbjct: 59 VAVLKREKKDADHIIKEMREVGEEIKKLDEELRTVEAELDTILLSIPNIPHESVPVGETE 118
Query: 121 EDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARAAKV 180
+DNV +R WG E + PK H D+ + LG DF RAAKV
Sbjct: 119 DDNVEVRKWG--------------------EKPSFAYEPKPHWDIADELGILDFERAAKV 158
Query: 181 SGSRFYYLLNEIVILDLALIRFALDELIKK-GFTPVIPPYMVRRFVEEGSTTFEDFEDVI 239
+GSRF + L+ AL F LD + + +T VIPPYMV R G+ FE+
Sbjct: 159 TGSRFVFYKGLGARLERALYNFMLDLHVDEYNYTEVIPPYMVNRASMTGTGQLPKFEEDA 218
Query: 240 YKVEGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKGIFRV 299
+K+ ED +LIPTAE P+ MH +EIL G LP+ Y S CFR EAG+AG+DT+G+ R
Sbjct: 219 FKIREEDYFLIPTAEVPITNMHRDEILSGDSLPINYAAFSACFRSEAGSAGRDTRGLIRQ 278
Query: 300 HQFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKYDIE 359
HQF+KVE + +PE+S+E E++ AE + Q LE+PYRV+++CTGDLG+ AAKKYDIE
Sbjct: 279 HQFNKVELVKFVKPEDSYEELEKLTNQAERVLQLLELPYRVMSMCTGDLGFTAAKKYDIE 338
Query: 360 AWMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIVAILE 419
W+P Q +RE+ S SN +QARR NIRFR KP +VHTLN + +A R + AILE
Sbjct: 339 VWIPSQDTYREISSCSNFEAFQARRANIRFRREAKGKPEHVHTLNGSGLAVGRTVAAILE 398
Query: 420 NHQEEDGTVKIPKVLWKYTGFKEIV 444
N+Q+EDG+V IPKVL Y G +E++
Sbjct: 399 NYQQEDGSVVIPKVLRPYMGNREVM 423
>sp|Q39230|SYS_ARATH SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) (SERRS)
>gi|2129737|pir||S71293 serine--tRNA ligase (EC
6.1.1.11) - Arabidopsis thaliana
>gi|1359497|emb|CAA94388.1| (Z70313) seryl-tRNA
Synthetase [Arabidopsis thaliana]
Length = 451
Score = 344 bits (874), Expect = 1e-93
Identities = 188/459 (40%), Positives = 280/459 (60%), Gaps = 31/459 (6%)
Query: 1 MLDIKLIRE----NPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNK 56
MLDI L RE NPE+++ ++R ++ +DEI+KLD EWR + E++ R E NK
Sbjct: 1 MLDINLFREEKGNNPEIIRESQRRR--FASVEIVDEIIKLDKEWRQRQFEVDSFRKEFNK 58
Query: 57 IAIEIGKRRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPI 116
+ ++ + + K E E++ ++++ + + E EV E + L ++ N+ H SVP+
Sbjct: 59 LNKQVAQLKIKKEDASEIIQQTEKNKQDSTAKEAEVREAYAALKAKLEQVGNLVHDSVPV 118
Query: 117 GESEEDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFAR 176
+ E +N+ I+ WG+ R + + K HVDL+E+LG AD R
Sbjct: 119 DKDEANNLVIKLWGEKR------------------FSTPGLKLKNHVDLVELLGIADTKR 160
Query: 177 AAKVSGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEGSTTFEDFE 236
A+++G+R ++L + ++L+ ALI F L L K+GFT + PP+ +R+ V F+
Sbjct: 161 GAEIAGARGFFLKGDGLMLNQALINFGLTFLKKRGFTGLQPPFFMRKDVMAKCAQLAQFD 220
Query: 237 DVIYKV--EGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTK 294
+ +YKV EG+D YLI TAE PL H +E + +LPL Y G S CFRKEAG+ G+DT
Sbjct: 221 EELYKVTGEGDDKYLIATAEQPLCAYHIDEWIHPTELPLRYAGYSSCFRKEAGSHGRDTL 280
Query: 295 GIFRVHQFHKVEQFVYSRPEE--SWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVA 352
GIFRVHQF K+EQF + P E SWE + +++N+E+ +Q L++PY++V+I +G L A
Sbjct: 281 GIFRVHQFEKIEQFCITGPNENASWEMLDEMMKNSEDFYQALKLPYQIVSIVSGALNDAA 340
Query: 353 AKKYDIEAWMPGQGRFREVVSASNCTDWQARRLNIRF--RDRTDEKPRYVHTLNSTAIAT 410
AKKYD+EAW P FRE+VS SNCTD+QARRL IR+ + ++ +YVH LNST AT
Sbjct: 341 AKKYDLEAWFPSSETFRELVSCSNCTDYQARRLEIRYGQKKSNEQTKQYVHMLNSTLTAT 400
Query: 411 SRAIVAILENHQEEDGTVKIPKVLWKYTGFKEIVPVEKK 449
R I ILEN+Q EDG V IP+VL + G + +P + K
Sbjct: 401 ERTICCILENYQREDG-VDIPEVLQPFMGGETFLPFKAK 438
>sp|P95689|SYS_STAAU SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) (SERRS)
>gi|1835218|emb|CAA71057.1| (Y09924) seryl-trna
synthetase [Staphylococcus aureus]
Length = 428
Score = 344 bits (873), Expect = 1e-93
Identities = 178/442 (40%), Positives = 267/442 (60%), Gaps = 23/442 (5%)
Query: 1 MLDIKLIRENPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIE 60
MLDI+L R P+ VK+ ++ RG+ K+ +DEIL+LD + R + +++ RNK++ E
Sbjct: 1 MLDIRLFRNEPDTVKSKIELRGDDPKV--VDEILELDEQRRKLISATEEMKARRNKVSEE 58
Query: 61 IGKRRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGESE 120
I +++ E ++++A+ + + I+ + ++ E+ K+ L R+PN+ VP GES+
Sbjct: 59 IALKKRNKENADDVIAEMRTLGDDIKEKDSQLNEIDNKMTGILCRIPNLISDDVPQGESD 118
Query: 121 EDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARAAKV 180
EDNV ++ WG R + + PK H D++E L ADF RAAKV
Sbjct: 119 EDNVEVKKWGTPREFS--------------------FEPKAHWDIVEELKMADFDRAAKV 158
Query: 181 SGSRFYYLLNEIVILDLALIRFALDE-LIKKGFTPVIPPYMVRRFVEEGSTTFEDFEDVI 239
SG+RF YL NE L+ AL+ + + + + G+T ++ P +V G+ FE+ +
Sbjct: 159 SGARFVYLTNEGAQLERALMNYMITKHTTQHGYTEMMVPQLVNADTMYGTGQLPKFEEDL 218
Query: 240 YKVEGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKGIFRV 299
+KVE E LY IPTAE PL + NEI+ LP + G S CFR EAG+AG+DT+G+ R+
Sbjct: 219 FKVEKEGLYTIPTAEVPLTNFYRNEIIQPGVLPEKFTGQSACFRSEAGSAGRDTRGLIRL 278
Query: 300 HQFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKYDIE 359
HQF KVE + +PE+SW E + NAE + ++L +PYR V +CTGD+G+ A+K YD+E
Sbjct: 279 HQFDKVEMVRFEQPEDSWNALEEMTTNAEAILEELGLPYRRVILCTGDIGFSASKTYDLE 338
Query: 360 AWMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIVAILE 419
W+P ++E+ S SNCTD+QARR NIRF+ KP HTLN + +A R AI+E
Sbjct: 339 VWLPSYNDYKEISSCSNCTDFQARRANIRFKRDKAAKPELAHTLNGSGLAVGRTFAAIVE 398
Query: 420 NHQEEDGTVKIPKVLWKYTGFK 441
N+Q EDGTV IP+ L + G K
Sbjct: 399 NYQNEDGTVTIPEALVPFMGGK 420
>sp|O81983|SYS_HELAN SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) (SERRS)
>gi|7489343|pir||T31430 serine--tRNA ligase (EC
6.1.1.11) - common sunflower >gi|3451411|emb|CAB11470.1|
(Z98761) seryl-tRNA synthetase [Helianthus annuus]
Length = 438
Score = 341 bits (866), Expect = 8e-93
Identities = 193/459 (42%), Positives = 269/459 (58%), Gaps = 34/459 (7%)
Query: 1 MLDIKLIRE----NPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNK 56
MLDI L RE NPE+V+ ++RG +I +DEI+KLD EWR + E+ +LR + N+
Sbjct: 1 MLDINLFREEKGGNPEIVRESQRRRGASVEI--VDEIIKLDKEWRQRQFELEQLRKDFNR 58
Query: 57 IAIEIGKRRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPI 116
I E+ K R G L+ ++E + EV+E + + L + N+ H SVP+
Sbjct: 59 INKEVAKLRISGGDASSLIKNTEENKDSTAKKQAEVQEARTALYSKLETVGNLVHDSVPV 118
Query: 117 GESEEDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFAR 176
E DN +R WG+ R E K HV+L+E+LG AD +
Sbjct: 119 SNDEADNAVVRTWGERRE---------------------ETNLKNHVELVELLGIADLKK 157
Query: 177 AAKVSGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEGSTTFEDFE 236
A V+G R YYL + V L+ ALI F LD L K+ +T + P+ +R+ + F+
Sbjct: 158 GANVAGGRGYYLKGDGVRLNQALINFGLDFLEKRKYTALQTPFFMRKDIMGKCAQLAQFD 217
Query: 237 DVIYKV--EGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTK 294
+ +YKV EG+D YLI TAE PL H ++ + +LPL Y G S CFRKEAG+ G+DT
Sbjct: 218 EELYKVTGEGDDKYLIATAEQPLCAYHIDDWIHPNELPLRYAGYSSCFRKEAGSHGRDTL 277
Query: 295 GIFRVHQFHKVEQFVYSRPE--ESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVA 352
GIFRVHQF KVEQF ++P +SWE HE +I+N+EE +Q L++PY+VV+I +G L A
Sbjct: 278 GIFRVHQFEKVEQFCLTKPSGNDSWEMHEEMIKNSEEFYQMLKLPYQVVSIVSGALNDAA 337
Query: 353 AKKYDIEAWMPGQGRFREVVSASNCTDWQARRLNIRFRDR--TDEKPRYVHTLNSTAIAT 410
AKKYD+EAW P +RE+VS SNCTD+Q+R+L IR + ++ +Y H LNST AT
Sbjct: 338 AKKYDLEAWFPASKTYRELVSCSNCTDYQSRKLEIRCGQKKGNEQAKQYCHLLNSTLTAT 397
Query: 411 SRAIVAILENHQEEDGTVKIPKVLWKYTGFKEIVPVEKK 449
R + ILEN+Q E G V IP+VL + G K + KK
Sbjct: 398 ERTLCCILENYQTEKG-VAIPEVLQPFMGGKTFLDFLKK 435
>dbj|BAB03743.1| (AP001507) seryl-tRNA synthetase [Bacillus halodurans]
Length = 425
Score = 339 bits (860), Expect = 4e-92
Identities = 174/443 (39%), Positives = 269/443 (60%), Gaps = 23/443 (5%)
Query: 1 MLDIKLIRENPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIE 60
MLDIK +R++ ++ L+ RGE I +++ LD + R + ++ +L+ RN+++ E
Sbjct: 1 MLDIKRLRKDFAGIREKLQTRGE--DISGLEKFGSLDEKRRQVIVKVEELKSRRNQVSQE 58
Query: 61 IGKRRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGESE 120
+ + +++ + + L+ + +++ I+ L++ + +L +++D L +PN+ H S P+GE+E
Sbjct: 59 VAQLKREKKDADHLIKEMRDVSDEIKGLDETLRQLDEELDQLLLAIPNVPHESTPVGETE 118
Query: 121 EDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARAAKV 180
+DNV +R WG E + PK H DL LG DF RAAKV
Sbjct: 119 DDNVEVRKWG--------------------EVPNFPFEPKAHWDLATALGIVDFERAAKV 158
Query: 181 SGSRFYYLLNEIVILDLALIRFALD-ELIKKGFTPVIPPYMVRRFVEEGSTTFEDFEDVI 239
+GSRF + L+ ALI F +D K G+ V+PPY+V R G+ FE+
Sbjct: 159 TGSRFAFYKGAGARLERALINFMMDLHHDKHGYEEVLPPYLVNRTSMTGTGQLPKFEEDA 218
Query: 240 YKVEGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKGIFRV 299
+K+ ED +LIPTAE P+ +H +EIL LP+ Y S FR EAG+AG+DT+G+ R
Sbjct: 219 FKIREEDYFLIPTAEVPVTNLHRDEILSADQLPIAYTAYSMNFRSEAGSAGRDTRGLIRQ 278
Query: 300 HQFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKYDIE 359
HQF+KVE + PE+S++ E++ +AE++ Q L++PYRV+++CT DLG+ AAKKYD+E
Sbjct: 279 HQFNKVELVRFVAPEDSYDELEKLTGHAEKVLQLLKLPYRVMSMCTADLGFTAAKKYDLE 338
Query: 360 AWMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIVAILE 419
W+P +RE+ S SN D+QARR NI+FR K +VHTLN + +A R + AILE
Sbjct: 339 VWIPSANTYREISSCSNFEDFQARRANIKFRREAKGKAEFVHTLNGSGLAVGRTVAAILE 398
Query: 420 NHQEEDGTVKIPKVLWKYTGFKE 442
N+Q+EDGT+ IP+VL Y G E
Sbjct: 399 NYQQEDGTIVIPEVLRPYMGGME 421
>sp|Q9ZBX1|SYS_STRCO SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) (SERRS)
>gi|7481765|pir||T36067 seryl-tRNA synthase -
Streptomyces coelicolor >gi|3928737|emb|CAA22233.1|
(AL034355) seryl-tRNA synthase [Streptomyces coelicolor
A3(2)]
Length = 425
Score = 332 bits (843), Expect = 4e-90
Identities = 182/449 (40%), Positives = 274/449 (60%), Gaps = 25/449 (5%)
Query: 1 MLDIKLIRENPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIE 60
M+D++L+RE+P+ V+ + RGE + +D +L D R+ ++LR E+ +
Sbjct: 1 MIDLRLLREDPDRVRASQRARGE--DVALVDSLLSADERRRSSGVRFDELRAEQKGLGKL 58
Query: 61 IGKRRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGESE 120
IGK G+ ELL +++++ +++ + E + + L RL N+ HP VP+G E
Sbjct: 59 IGKAA--GDEKAELLKRAEQLKTDVKAADAERDAADAETQELLQRLGNLVHPDVPVG-GE 115
Query: 121 EDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARAAKV 180
ED V + G R ++ + P+ H++L ++LG D R AKV
Sbjct: 116 EDFVTLETHGTHR-----------------DFAAEGFEPRDHLELGQLLGAIDVERGAKV 158
Query: 181 SGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEGSTTFEDFEDVIY 240
SGSRFY+L +L+LAL+ A+ + GFTP++ P +VR G+ +Y
Sbjct: 159 SGSRFYFLTGVGALLELALVNAAIAQATAAGFTPMLTPALVRPQSMAGTGFLGQAAQDVY 218
Query: 241 KVEGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKGIFRVH 300
++ +DLYL+ T+E PLA H +EILDG LPL Y G SPCFR+EAG+ GKDT+GIFRVH
Sbjct: 219 HLDKDDLYLVGTSEVPLAAYHMDEILDGDRLPLRYAGFSPCFRREAGSHGKDTRGIFRVH 278
Query: 301 QFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKYDIEA 360
QF KVE F Y PE+S H+R++ ++ LE+P+RV+++ + DLG AA+KYD EA
Sbjct: 279 QFDKVEMFSYVLPEDSQAEHQRLLEWEKQWLTSLELPFRVIDVASADLGSSAARKYDCEA 338
Query: 361 WMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIVAILEN 420
W+P QG++RE+ S S+CT++Q+RRL+IR R+ +K R + TLN T A R IVAILEN
Sbjct: 339 WIPTQGKYRELTSTSDCTEFQSRRLSIRVRE--GKKVRPLATLNGTLCAVPRTIVAILEN 396
Query: 421 HQEEDGTVKIPKVLWKYTGFKEIV-PVEK 448
HQ+ DG+V++P+VL Y G +E++ PV K
Sbjct: 397 HQQADGSVRVPEVLRPYLGGREVLEPVAK 425
>sp|O51244|SYS_BORBU SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) (SERRS)
>gi|7437681|pir||B70128 serine--tRNA ligase (EC
6.1.1.11) serS - Lyme disease spirochete
>gi|2688129|gb|AAC66622.1| (AE001133) seryl-tRNA
synthetase (serS) [Borrelia burgdorferi]
Length = 425
Score = 330 bits (838), Expect = 2e-89
Identities = 194/447 (43%), Positives = 279/447 (62%), Gaps = 30/447 (6%)
Query: 1 MLDIKLIRENPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIE 60
MLD+K IR+N +LVK +K RG + ID+++ LD + + + +I +L +RN+ + +
Sbjct: 1 MLDLKFIRDNLDLVKRSIKARG---LVLDIDKLIYLDDKRKKLITKIGELNAKRNENSSK 57
Query: 61 IGKRRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGESE 120
+ + K + L+ K + K++ LE+E+E + D ++PNI P VPIG SE
Sbjct: 58 MQENLDKVLKIS-LIETGKILKKQLIDLEEELERVSVDFDLENKKVPNILSPDVPIGSSE 116
Query: 121 EDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARAAKV 180
EDN I+ RV G + +F +++PK H++L L DF RA ++
Sbjct: 117 EDNFEIK-----RV--GVVPQF-------------DFKPKDHLELGRDLDLLDFDRAREI 156
Query: 181 SGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEG-STTFEDFEDVI 239
SGS+FYYL NE V L++ALI F+L++L KGF I P + R F+ +G E I
Sbjct: 157 SGSKFYYLKNEAVFLEIALINFSLNKLRDKGFDVFITPDVAREFIVDGIGFNPRGNESNI 216
Query: 240 YKVEGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKGIFRV 299
YK+E D YL+ T+E L G + N+I+D LP+ G S CFRKEAG G+ +KG++RV
Sbjct: 217 YKIEDTDKYLVGTSEITLGGYYYNKIID-LTLPIRMAGFSHCFRKEAGAYGQLSKGLYRV 275
Query: 300 HQFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKYDIE 359
HQF KVE F + + EES H+ + E++F +LEIPYRV+NIC+ DLG A KKYDIE
Sbjct: 276 HQFSKVEMFCFCKAEESGVIHDEFLSIQEQIFTELEIPYRVLNICSFDLGSPAYKKYDIE 335
Query: 360 AWMP---GQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIVA 416
AWMP G+G + EV S SNCTD+Q+RRL IR++D+ D + ++ H +N TAIAT+R I++
Sbjct: 336 AWMPGRDGKGGYGEVTSTSNCTDYQSRRLKIRYKDQ-DGQNKFAHMVNGTAIATTRVIIS 394
Query: 417 ILENHQEEDGTVKIPKVLWKYTGFKEI 443
ILEN Q++ G V+IPK L KYTGF I
Sbjct: 395 ILENFQDQKGGVRIPKSLVKYTGFDYI 421
>pir||G75414 seryl-tRNA synthetase - Deinococcus radiodurans (strain R1)
>gi|6459024|gb|AAF10848.1|AE001975_2 (AE001975)
seryl-tRNA synthetase [Deinococcus radiodurans]
Length = 425
Score = 327 bits (829), Expect = 2e-88
Identities = 182/447 (40%), Positives = 269/447 (59%), Gaps = 30/447 (6%)
Query: 1 MLDIKLIRENPELVKNDLK-KRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAI 59
MLD+K IRENP+ V+ ++ K L+ +D++L+ D + A + + ++ ERN A
Sbjct: 1 MLDLKFIRENPDAVREAIRVKNVALD----LDDLLQRDRDLVALKQRVEAMQTERNANAK 56
Query: 60 EIGKRRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGES 119
+ K + P L+ K K++ + +++LE ++ E + + L R+PNI P VP+G+
Sbjct: 57 LVPKASPEDRP--GLIQKGKDLSEDLKALEPQLREQEDALKQLLLRVPNIPLPGVPVGKD 114
Query: 120 EEDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARAAK 179
E+DNV +R EG L F ++ P V++LE G ADF R A+
Sbjct: 115 EDDNVELRR-------EGELPGF-------------DFTPLDQVEILEKQGWADFERVAR 154
Query: 180 VSGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEGSTTFEDFEDVI 239
VSGSR Y L + +L++A++ FALD L ++GFTP+ +VRR S F E+ +
Sbjct: 155 VSGSRSYLLKGDAALLEMAVLMFALDFLSQRGFTPLSTTALVRRETLVNSGHFPGDEESV 214
Query: 240 YKVEGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKGIFRV 299
YK+EG++L L TAE P+ ++A E L +LPL + G S FR+EAG+AG+D +G+ RV
Sbjct: 215 YKLEGDELLLAGTAEVPINSLYAGEQLSADELPLTFAGFSAAFRREAGSAGRDVRGLIRV 274
Query: 300 HQFHKVEQFVYSR--PEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKYD 357
H+F KVEQ+V R EE +W ER++ NAE L Q LE+PYRV+ CTGD+G YD
Sbjct: 275 HEFRKVEQYVLCRADQEEGLKWFERLLSNAEGLLQALELPYRVIQNCTGDMGAGKVLMYD 334
Query: 358 IEAWMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIVAI 417
IE W+P + ++RE S S DWQARR +R+RD K Y HTLN+T IA+ R +V +
Sbjct: 335 IETWVPSEQKYRETHSCSYLGDWQARRTGLRYRDE-HGKLLYAHTLNNTGIASPRILVPL 393
Query: 418 LENHQEEDGTVKIPKVLWKYTGFKEIV 444
LENHQ+ DGTV++P L Y G +E++
Sbjct: 394 LENHQQADGTVRVPAALRPYLGGREVL 420
>pir||T02786 serine--tRNA ligase (EC 6.1.1.11) - maize
>gi|3319776|emb|CAA07600.1| (AJ007665) seryl-tRNA
synthetase [Zea mays]
Length = 457
Score = 316 bits (802), Expect = 3e-85
Identities = 179/460 (38%), Positives = 269/460 (57%), Gaps = 37/460 (8%)
Query: 1 MLDIKLIRE----NPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNK 56
MLDI L R NP+L++ +R ++ +DE++ LD WR + E++K+R + +
Sbjct: 1 MLDINLFRTDKGGNPDLIRES--QRSRFASVELVDEVIALDKAWRERQFELDKIR-QAQR 57
Query: 57 IAIEIGKRR--KKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSV 114
+ +IGK + K+ E ++L+ + EI KR+ + E EV+E K +D + + NI H SV
Sbjct: 58 TSKKIGKLKASKQEEEAKKLMESTDEIKKRLAAKEVEVQEAKSTLDAKVTTIGNIVHESV 117
Query: 115 PIGESEEDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADF 174
P+ + E +N +R +G+ RV E K HVDL +L
Sbjct: 118 PVSDDEANNKIVRTFGEKRV---------------------EDNLKNHVDLCRMLDIVAL 156
Query: 175 ARAAKVSGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEGSTTFED 234
+ A V+G R +YL +E V+L+LALI F L L K+GF P+ P+ +R+
Sbjct: 157 EKGADVAGGRGFYLKDEGVLLNLALINFGLAFLRKRGFKPMQTPFFMRKETMAKCAQLAQ 216
Query: 235 FEDVIYKV--EGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKD 292
F++ +YKV +GED YLI T+E PL H + + +LP+ Y G S CFRKEAG+ G+D
Sbjct: 217 FDEELYKVTGDGEDKYLIATSEQPLCAYHLGDRIYPAELPIKYAGYSTCFRKEAGSHGRD 276
Query: 293 TKGIFRVHQFHKVEQFVYSRPE--ESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGY 350
T GIFRVHQF K+EQF + P +SWE HE +++N+E+ ++++ +PY+VV+I +G L
Sbjct: 277 TAGIFRVHQFEKIEQFCITSPNGNDSWEIHEEMLKNSEDFYKEIGLPYQVVSIVSGALND 336
Query: 351 VAAKKYDIEAWMPGQGRFREVVSASNCTDWQARRLNIRF--RDRTDEKPRYVHTLNSTAI 408
AAKKYD+EAW P FRE+VS SNCTD+ RRL I + + ++ ++VH LNST
Sbjct: 337 AAAKKYDLEAWFPASKTFRELVSCSNCTDFSQRRLGIGYGQKKNDEQSKQFVHMLNSTLT 396
Query: 409 ATSRAIVAILENHQEEDGTVKIPKVLWKYTGFKEIVPVEK 448
AT R + ILEN Q+EDG ++ L Y G E +P ++
Sbjct: 397 ATERTLCCILENFQKEDGR-RVKGTLQPYMGGIEFLPFKQ 435
>sp|P96244|SYS_MYCTU SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) (SERRS)
>gi|7437687|pir||G70652 probable serS protein -
Mycobacterium tuberculosis (strain H37RV)
>gi|1781123|emb|CAB06207.1| (Z83864) serS [Mycobacterium
tuberculosis]
Length = 419
Score = 316 bits (801), Expect = 3e-85
Identities = 180/446 (40%), Positives = 258/446 (57%), Gaps = 28/446 (6%)
Query: 1 MLDIKLIRENPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIE 60
M+D+KL+RENP+ V+ RGE + +D +L DA RA + + LR E+ +
Sbjct: 1 MIDLKLLRENPDAVRRSQLSRGEDPAL--VDALLTADAARRAVISTADSLRAEQKAASKS 58
Query: 61 IGKRRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGESE 120
+G + P LL ++KE+ +++++ E + E + + N+ VP G E
Sbjct: 59 VGGASPEERP--PLLRRAKELAEQVKAAEADEVEAEAAFTAAHLAISNVIVDGVPAG-GE 115
Query: 121 EDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARAAKV 180
+D + G+ E PK H++L E LG D R AKV
Sbjct: 116 DDYAVLDVVGEPSYLEN---------------------PKDHLELGESLGLIDMQRGAKV 154
Query: 181 SGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEGSTTFEDFEDVIY 240
SGSRFY+L +L L L++ AL + GF P IPP +VR V G+ + +Y
Sbjct: 155 SGSRFYFLTGRGALLQLGLLQLALKLAVDNGFVPTIPPVLVRPEVMVGTGFLGAHAEEVY 214
Query: 241 KVEGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKGIFRVH 300
+VEG+ LYL+ T+E PLAG H+ EILD PL Y G S CFR+EAG+ GKDT+GI RVH
Sbjct: 215 RVEGDGLYLVGTSEVPLAGYHSGEILDLSRGPLRYAGWSSCFRREAGSHGKDTRGIIRVH 274
Query: 301 QFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKYDIEA 360
QF KVE FVY P ++ HER++ ++ ++E+PYRV+++ GDLG AA+K+D EA
Sbjct: 275 QFDKVEGFVYCTPADAEHEHERLLGWQRQMLARIEVPYRVIDVAAGDLGSSAARKFDCEA 334
Query: 361 WMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIVAILEN 420
W+P QG +RE+ S SNCT +QARRL R+RD + KP+ TLN T +AT+R +VAILEN
Sbjct: 335 WIPTQGAYRELTSTSNCTTFQARRLATRYRDASG-KPQIAATLNGT-LATTRWLVAILEN 392
Query: 421 HQEEDGTVKIPKVLWKYTGFKEIVPV 446
HQ DG+V++P L + G + + PV
Sbjct: 393 HQRPDGSVRVPDALVPFVGVEVLEPV 418
>pir||T03949 serine--tRNA ligase (EC 6.1.1.11) serS - maize (fragment)
>gi|3355717|emb|CAA73496.1| (Y13053) seryl-tRNA
synthetase [Zea mays]
Length = 489
Score = 314 bits (797), Expect = 1e-84
Identities = 182/460 (39%), Positives = 269/460 (57%), Gaps = 44/460 (9%)
Query: 2 LDIKLIRENPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIEI 61
+D K IR+N + V ++++ R + D + +L ++ KE+ +LR ERN +A
Sbjct: 52 IDFKWIRDNRDAVADNIRTRNSTANL---DLVFELYDQYLTLQKEVERLRAERNAVA--- 105
Query: 62 GKRRKKGEPV--EELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGES 119
K + K +P + L+ + K + + + +LE+++ +L K+ +PN THP VP+G
Sbjct: 106 NKMKGKLDPSVRQALVEEGKNLKEGLIALEEDLVQLTDKLQLEAQSIPNTTHPDVPVG-G 164
Query: 120 EEDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARAAK 179
EE +V + G SQ + + K H+ L + L DF AA+
Sbjct: 165 EESSVLRKEVG---------------SQRSFNFAI-----KDHLQLGKELDLFDFDAAAE 204
Query: 180 VSGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEGSTTFEDFEDVI 239
VSGS+FYYL NE V+L++AL+ +A+ E+ KKGFTP+I P +VR V E + +
Sbjct: 205 VSGSKFYYLKNEAVLLEMALVIWAISEVSKKGFTPLITPEIVRSSVVEKCGFSKGKNTQV 264
Query: 240 YKVEGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKGIFRV 299
Y +E D LI TAE P+ G+H + IL LPL YV S CFR EAG AG T+G++RV
Sbjct: 265 YSIEDSDQCLIGTAEIPVGGIHMDSILAESALPLKYVAYSHCFRTEAGAAGAATRGLYRV 324
Query: 300 HQFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKYDIE 359
HQF KVE F++ RPEES +WHE +I E+L+ L + ++ +++ TGDLG A +K+DIE
Sbjct: 325 HQFSKVEMFIFCRPEESGKWHEELITIEEDLYASLGLHFKTLDMATGDLGAPAYRKFDIE 384
Query: 360 AWMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKP---------------RYVHTLN 404
AWMPG R+ E+ SASNCTD+Q+RRL IR+R E P ++VHTLN
Sbjct: 385 AWMPGLERYGEISSASNCTDYQSRRLGIRYRPSPSEPPSTSTKKGKGAASGPTQFVHTLN 444
Query: 405 STAIATSRAIVAILENHQEEDGTVKIPKVLWKYTGFKEIV 444
+TA+A R IV ILEN Q+ DG++ +P+ L Y G E++
Sbjct: 445 ATAVAVPRLIVCILENFQQGDGSIVVPEPLRPYMGGLELL 484
>sp|P54221|SYS_HALMA SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) (SERRS)
>gi|11271533|pir||T47108 serine--tRNA ligase (EC
6.1.1.11) [validated] - Haloarcula marismortui
>gi|1004231|emb|CAA62489.1| (X91007) seryl-tRNA
synthetase [Haloarcula marismortui]
Length = 460
Score = 312 bits (791), Expect = 5e-84
Identities = 180/468 (38%), Positives = 269/468 (57%), Gaps = 39/468 (8%)
Query: 1 MLDIKLIRENPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIE 60
ML + +RE+PE V++ ++++G +DEIL +D EWR E + LR ERN+++ +
Sbjct: 1 MLSRQFVREHPETVRDAIERKGVTGVD--LDEILDIDEEWRELKAEGDGLRQERNEVSSK 58
Query: 61 IGKRRKKG--EPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGE 118
IG+ ++ G E +E + +S+E+ ++ +E+ +EL+ +++ L LPNI H SVP GE
Sbjct: 59 IGELKQDGKDEEAQEAIDRSQELKDELQDIEERADELESQLEEALLELPNIPHESVPTGE 118
Query: 119 SEEDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARAA 178
E DNV ER+ E G + L H DL E L DF R A
Sbjct: 119 GEADNV---------------ERYRE---GFDDLRDLPDEVVPHYDLGEDLDLLDFERGA 160
Query: 179 KVSGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEGSTTFEDFEDV 238
KVSG + ++ E L+ ALI+F LD ++ + V+PP V EG+ F +
Sbjct: 161 KVSGGGYQFVKGEGARLEHALIQFMLDVHREQEYVDVLPPIPVNSDSMEGTGQLPKFAED 220
Query: 239 IYKV--------EGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAG 290
Y+V + +DL+L+PTAE P+ M+ EIL DLP+ + SP FR+EAG G
Sbjct: 221 AYRVGARQDDDYDSDDLWLLPTAEVPVTNMYRGEILLDDDLPVKHQAFSPNFRREAGEHG 280
Query: 291 KDTKGIFRVHQFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGY 350
+T+G RVHQFHKVE + RPE S++ E ++ A E+ +LE+PYRV+++CTGD+G+
Sbjct: 281 TETRGYVRVHQFHKVELVNFVRPENSYDRLESLLDEAAEVLDRLELPYRVLDMCTGDMGF 340
Query: 351 VAAKKYDIEAWMPGQ---------GRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVH 401
AKKYDIE W PG GR+ EV S SN D+QARR +R+R E Y+H
Sbjct: 341 TQAKKYDIEVWAPGDDMEDGPDRGGRWLEVSSVSNFEDFQARRAGLRYRPERHESADYLH 400
Query: 402 TLNSTAIATSRAIVAILENHQEEDGTVKIPKVLWKYTGFKEIVPVEKK 449
TLN + +A R +VAI+E +Q +DGT+ +P+ L Y G +E++ +K
Sbjct: 401 TLNGSGLAVPRVLVAIMEYYQNDDGTITVPEPLRPYMGGQEVIEGSEK 448
>gb|AAG03084.1|AF297553_1 (AF297553) seryl-tRNA synthetase [Bos taurus]
Length = 514
Score = 307 bits (779), Expect = 1e-82
Identities = 187/496 (37%), Positives = 277/496 (55%), Gaps = 73/496 (14%)
Query: 1 MLDIKLIREN----PELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNK 56
+LD+ L R + P L++ +KR + + +D+++K D+EWR + L +N
Sbjct: 2 VLDLDLFRVDKGGDPALIRESQEKRFKDPGL--VDQLVKADSEWRRCRFRADNLNKLKNL 59
Query: 57 IAIEIGKRRKKGEPV------------------EELLAKSKEIVKRIESLEKEV------ 92
+ IG++ KK EPV + L +K++ L E
Sbjct: 60 CSKTIGEKMKKKEPVGNDESIPEDVLNLDDLTADTLTNLKVSQIKKVRLLVDEAILKCDA 119
Query: 93 EELKKKIDYY--LWRLPNITHPSVPIGESEE-DNVPIRFWGKARVWEGHLERFLEQSQGK 149
E +K + + + L + N+ HPSVPI + E+ DN R WG V +
Sbjct: 120 ERIKLEAERFESLREIGNLLHPSVPISDDEDADNKVERIWGDCTV--------------R 165
Query: 150 MEYEVLEWRPKLHVDLLEILGGADFARAAKVSGSRFYYLLNEIVILDLALIRFALDELIK 209
+Y HVDL+ ++ G + + A V+GSR Y+L +V L+ ALI+FAL L
Sbjct: 166 KKYS--------HVDLVVMVDGFEGEKGAVVAGSRGYFLKGVLVFLEQALIQFALRTLAS 217
Query: 210 KGFTPVIPPYMVRRFVEEGSTTFEDFEDVIYKVEG-----------EDLYLIPTAEHPLA 258
+G+TP+ P+ +R+ V + F++ +YKV G E+ YLI T+E P+A
Sbjct: 218 RGYTPIYTPFFMRKEVMQEVAQLSQFDEELYKVIGKGSEKSDDNSYEEKYLIATSEQPIA 277
Query: 259 GMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKGIFRVHQFHKVEQFVYSRPEE--S 316
+H +E L +DLP+ Y G+S CFR+E G+ G+DT+GIFRVHQF K+EQFVYS P + S
Sbjct: 278 ALHRDEWLRPEDLPIKYAGLSTCFRQEVGSHGRDTRGIFRVHQFEKIEQFVYSSPHDNKS 337
Query: 317 WEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKYDIEAWMPGQGRFREVVSASN 376
WE E +I AEE +Q L IPY +VNI +G L + A+KK D+EAW PG G FRE+VS SN
Sbjct: 338 WEMFEEMIATAEEFYQSLGIPYHIVNIVSGSLNHAASKKLDLEAWFPGSGAFRELVSCSN 397
Query: 377 CTDWQARRLNIRF--RDRTDEKPRYVHTLNSTAIATSRAIVAILENHQEEDGTVKIPKVL 434
CTD+QARRL IR+ + +K +VH LN+T AT+R I AILEN+Q E G + +P+ L
Sbjct: 398 CTDYQARRLRIRYGQTKKMMDKVEFVHMLNATMCATTRTICAILENYQTEKG-ILVPEKL 456
Query: 435 WKY--TGFKEIVPVEK 448
++ G +E++P K
Sbjct: 457 KEFMPPGLQELIPFVK 472
>pir||G83320 seryl-tRNA synthetase PA2612 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9948677|gb|AAG06000.1|AE004689_12
(AE004689) seryl-tRNA synthetase [Pseudomonas
aeruginosa]
Length = 426
Score = 305 bits (774), Expect = 5e-82
Identities = 171/449 (38%), Positives = 264/449 (58%), Gaps = 29/449 (6%)
Query: 1 MLDIKLIRENPELVKNDLKKRG-ELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAI 59
MLD KL+R P+ V L RG +L+ + I L+ + ++ +L+ ERN +
Sbjct: 1 MLDPKLVRTQPQEVAARLATRGFQLD----VARIEALEEQRKSVQTRTEQLQAERNARSK 56
Query: 60 EIGKRRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGES 119
IG+ +++GE + LLA + +E +++++ ++ ++D L +PN+ H SVP+G
Sbjct: 57 AIGQAKQRGEDIAPLLADVDRMGSELEEGKRQLDAIQGELDAMLLGIPNLPHESVPVGAD 116
Query: 120 EEDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARAAK 179
E+ NV +R WG + ++ +EV K HV L E G DF AAK
Sbjct: 117 EDANVEVRRWGTPKTFD---------------FEV-----KDHVALGERHGWLDFETAAK 156
Query: 180 VSGSRFYYLLNEIVILDLALIRFALD-ELIKKGFTPVIPPYMVRRFVEEGSTTFEDFEDV 238
+SG+RF + I L AL +F ++ + G+ PY+V+ +G+ FE+
Sbjct: 157 LSGARFALMRGPIARLHRALAQFMINLHTAEHGYEEAYTPYLVQAPALQGTGQLPKFEED 216
Query: 239 IYKV--EGE-DLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKG 295
++K+ +GE DLYLIPTAE L + + +ILD K LPL +V +PCFR EAG +G+DT+G
Sbjct: 217 LFKIGRDGEADLYLIPTAEVSLTNIVSGQILDAKQLPLKFVAHTPCFRSEAGASGRDTRG 276
Query: 296 IFRVHQFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKK 355
+ R HQF KVE P S+E E + NAE + Q LE+PYRV+ +CTGD+G+ A K
Sbjct: 277 MIRQHQFDKVEMVQIVDPATSYEALEGLTANAERVLQLLELPYRVLALCTGDMGFGATKT 336
Query: 356 YDIEAWMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIV 415
YD+E W+P Q ++RE+ S SNC D+QARR+ R+R+ KP VHTLN + +A R +V
Sbjct: 337 YDLEVWVPSQDKYREISSCSNCGDFQARRMQARYRNPETGKPELVHTLNGSGLAVGRTLV 396
Query: 416 AILENHQEEDGTVKIPKVLWKYTGFKEIV 444
A+LEN+Q+ DG++++P+VL Y E++
Sbjct: 397 AVLENYQQADGSIRVPEVLKPYMAGIEVI 425
>sp|O14018|SYSC_SCHPO SERYL-TRNA SYNTHETASE, CYTOPLASMIC (SERINE--TRNA LIGASE) (SERRS)
>gi|7493380|pir||T38474 serine--tRNA ligase (EC
6.1.1.11), cytosolic - fission yeast
(Schizosaccharomyces pombe) >gi|2440188|emb|CAB10149.1|
(Z97210) seryl-trna synthetase, cytoplasmic (EC
6.1.1.11) [Schizosaccharomyces pombe]
Length = 450
Score = 302 bits (765), Expect = 6e-81
Identities = 177/459 (38%), Positives = 261/459 (56%), Gaps = 31/459 (6%)
Query: 1 MLDIKLIRE----NPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNK 56
MLDI L + NPE+++ +KRG + +D+++++ EW + E++ N+
Sbjct: 1 MLDINLFQVEKGGNPEIIRESQRKRGA--DVGVVDKVIEMYKEWVSLRFELDNTNKSINR 58
Query: 57 IAIEIGKRRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPI 116
+ EIG + K E ELL + + +R ++L ++ K++ + + NI H SVP+
Sbjct: 59 VQKEIGLKMKAKEDASELLEEKNSLTERKKNLIEQETAKNKEMLNVVSSIGNIVHDSVPV 118
Query: 117 GESEEDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFAR 176
E++N IR W V +E+ +EVL L G D R
Sbjct: 119 SMDEDNNEIIRKWAPEGVT-------VEKKNCLSHHEVLTR-----------LDGYDPER 160
Query: 177 AAKVSGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEGSTTFEDFE 236
KVSG R Y+L V +LALI++ LD L K+G+ + P M+ + V + E F+
Sbjct: 161 GVKVSGHRGYFLRQYGVFFNLALIQYGLDFLEKRGYIALQAPTMLNKDVMAKTAQLEQFD 220
Query: 237 DVIYKV--EGEDLYLIPTAEHPLAGMHANEILD--GKDLPLLYVGISPCFRKEAGTAGKD 292
+ +YKV E+ YLI T+E P++ H+ E + + LPL Y G S C+R+EAG+ G+D
Sbjct: 221 EELYKVIDGDEERYLIATSEQPISAYHSGEWFEKPSEQLPLKYAGYSTCYRREAGSHGRD 280
Query: 293 TKGIFRVHQFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVA 352
GIFRVH F K+EQFV + PE+SWE +I +AE+ ++ LE+PYR+V I +G L A
Sbjct: 281 AWGIFRVHAFEKIEQFVLTDPEKSWEAFTEMINHAEDFYKSLELPYRIVAIVSGALNNAA 340
Query: 353 AKKYDIEAWMPGQGRFREVVSASNCTDWQARRLNIR--FRDRTDEKPRYVHTLNSTAIAT 410
AKKYD+EAW P QG ++E+VS SNCTD+Q+R L IR + D + +YVH LNST AT
Sbjct: 341 AKKYDLEAWFPFQGEYKELVSCSNCTDYQSRNLEIRCGVKKMGDREKKYVHCLNSTLCAT 400
Query: 411 SRAIVAILENHQEEDGTVKIPKVLWKYTGFKEIVPVEKK 449
RA+ ILEN+Q DG V +PKVL Y G K +P K+
Sbjct: 401 ERALCCILENYQTPDG-VNVPKVLQPYMGGKTFLPFTKE 438
>sp|P73201|SYS_SYNY3 SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) (SERRS)
>gi|7437673|pir||S75313 serine--tRNA ligase (EC
6.1.1.11) - Synechocystis sp. (strain PCC 6803)
>gi|1652304|dbj|BAA17227.1| (D90904) seryl-tRNA
synthetase [Synechocystis sp.]
Length = 430
Score = 301 bits (763), Expect = 1e-80
Identities = 169/440 (38%), Positives = 260/440 (58%), Gaps = 25/440 (5%)
Query: 1 MLDIKLIRENPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIE 60
MLD+K IRENP ++N L +RG ++ IL + AE +AK E L+ N+I
Sbjct: 1 MLDLKQIRENPTAIQNRLNQRGGGASYD-LEPILAIAAEQKAKESERTVLQSRSNEIGKL 59
Query: 61 IGKR-----RKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVP 115
IG++ KGE ++ L + + ++ LE + ++LK+++ L LPN+ + P
Sbjct: 60 IGQKIGQGADPKGEEIQTLREEGNSLKIQLADLEPQEKDLKEQLQKLLLELPNLPCETTP 119
Query: 116 IGESEEDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFA 175
IG SE DN+ ++ WG +++L+ E + P H ++ E LG D
Sbjct: 120 IGASEADNIEVKRWG---------DQYLKA-------ETVGILP--HWEIGEKLGIIDSE 161
Query: 176 RAAKVSGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEGSTTFEDF 235
R KV+ SRF L+ L+ ALI F L+ I G+ ++PP +V G+ F
Sbjct: 162 RGVKVAQSRFISLMKAGAALERALINFMLERHIGVGYQEIMPPILVNSDSLLGTGQLPKF 221
Query: 236 EDVIYKVEGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKG 295
+ ++ G+DL+LIPTAE P+ ++ +E+LD + LP+ + +PCFR+EAG+ G+DTKG
Sbjct: 222 AEESFQCRGDDLWLIPTAEVPVTNLYRDEVLDLEQLPIKHCAYTPCFRREAGSYGRDTKG 281
Query: 296 IFRVHQFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKK 355
+ R+HQF+KVE +PEES H+ ++ +AE + Q LE+PYRVV +CTGDLG+ AAK
Sbjct: 282 LIRLHQFNKVELVKLVKPEESAAEHQALVADAEAILQALELPYRVVELCTGDLGFGAAKC 341
Query: 356 YDIEAWMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIV 415
YD+E W+P +RE+ S SN D+QARR NIR++++ + ++VHTLN + +A R +
Sbjct: 342 YDLEVWLPSANTYREISSCSNFHDFQARRANIRYKEKGKKGTQFVHTLNGSGLAIGRTMA 401
Query: 416 AILENHQE-EDGTVKIPKVL 434
AILEN+ E G VK+P VL
Sbjct: 402 AILENYYEPSSGQVKVPVVL 421
>dbj|BAA95602.1| (D49914) Seryl tRNA Synthetase [Homo sapiens]
Length = 514
Score = 301 bits (763), Expect = 1e-80
Identities = 186/496 (37%), Positives = 277/496 (55%), Gaps = 73/496 (14%)
Query: 1 MLDIKLIREN----PELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNK 56
+LD+ L R + P L++ +KR + + +D+++K D+EWR + L +N
Sbjct: 2 VLDLDLFRVDKGGDPALIRETQEKRFKDPGL--VDQLVKADSEWRRCRFRADNLNKLKNL 59
Query: 57 IAIEIGKRRKKGEPV-----------------EELLAKSK-EIVKRIESLEKEV------ 92
+ IG++ KK EPV + LA K +K++ L E
Sbjct: 60 CSKTIGEKMKKKEPVGDDESVPENVLSFDDLTADALANLKVSQIKKVRLLIDEAILKCDA 119
Query: 93 EELKKKIDYY--LWRLPNITHPSVPIGESEE-DNVPIRFWGKARVWEGHLERFLEQSQGK 149
E +K + + + L + N+ HPSVPI E+ DN R WG V +
Sbjct: 120 ERIKLEAERFENLREIGNLLHPSVPISNDEDVDNKVERIWGDCTV--------------R 165
Query: 150 MEYEVLEWRPKLHVDLLEILGGADFARAAKVSGSRFYYLLNEIVILDLALIRFALDELIK 209
+Y HVDL+ ++ G + + A V+GSR Y+L +V L+ ALI++AL L
Sbjct: 166 KKYS--------HVDLVVMVDGFEGEKGAVVAGSRGYFLKGVLVFLEQALIQYALRTLGS 217
Query: 210 KGFTPVIPPYMVRRFVEEGSTTFEDFEDVIYKVEG-----------EDLYLIPTAEHPLA 258
+G+ P+ P+ +R+ V + F++ +YKV G ++ YLI T+E P+A
Sbjct: 218 RGYIPIYTPFFMRKEVMQEVAQLSQFDEELYKVIGKGSEKSDDNSYDEKYLIATSEQPIA 277
Query: 259 GMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKGIFRVHQFHKVEQFVYSRPEE--S 316
+H +E L +DLP+ Y G+S CFR+E G+ G+DT+GIFRVHQF K+EQFVYS P + S
Sbjct: 278 ALHRDEWLRPEDLPIKYAGLSTCFRQEVGSHGRDTRGIFRVHQFEKIEQFVYSSPHDNKS 337
Query: 317 WEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKYDIEAWMPGQGRFREVVSASN 376
WE E +I AEE +Q L IPY +VNI +G L + A+KK D+EAW PG G FRE+VS SN
Sbjct: 338 WEMFEEMITTAEEFYQSLGIPYHIVNIVSGSLNHAASKKLDLEAWFPGSGAFRELVSCSN 397
Query: 377 CTDWQARRLNIRF--RDRTDEKPRYVHTLNSTAIATSRAIVAILENHQEEDGTVKIPKVL 434
CTD+QARRL IR+ + +K +VH LN+T AT+R I AILEN+Q E G + +P+ L
Sbjct: 398 CTDYQARRLRIRYGQTKKMMDKVEFVHMLNATMCATTRTICAILENYQTEKG-ITVPEKL 456
Query: 435 WKY--TGFKEIVPVEK 448
++ G +E++P K
Sbjct: 457 KEFMPPGLQELIPFVK 472
>gi|11428211 seryl-tRNA synthetase [Homo sapiens]
Length = 539
Score = 301 bits (763), Expect = 1e-80
Identities = 186/496 (37%), Positives = 277/496 (55%), Gaps = 73/496 (14%)
Query: 1 MLDIKLIREN----PELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNK 56
+LD+ L R + P L++ +KR + + +D+++K D+EWR + L +N
Sbjct: 27 VLDLDLFRVDKGGDPALIRETQEKRFKDPGL--VDQLVKADSEWRRCRFRADNLNKLKNL 84
Query: 57 IAIEIGKRRKKGEPV-----------------EELLAKSK-EIVKRIESLEKEV------ 92
+ IG++ KK EPV + LA K +K++ L E
Sbjct: 85 CSKTIGEKMKKKEPVGDDESVPENVLSFDDLTADALANLKVSQIKKVRLLIDEAILKCDA 144
Query: 93 EELKKKIDYY--LWRLPNITHPSVPIGESEE-DNVPIRFWGKARVWEGHLERFLEQSQGK 149
E +K + + + L + N+ HPSVPI E+ DN R WG V +
Sbjct: 145 ERIKLEAERFENLREIGNLLHPSVPISNDEDVDNKVERIWGDCTV--------------R 190
Query: 150 MEYEVLEWRPKLHVDLLEILGGADFARAAKVSGSRFYYLLNEIVILDLALIRFALDELIK 209
+Y HVDL+ ++ G + + A V+GSR Y+L +V L+ ALI++AL L
Sbjct: 191 KKYS--------HVDLVVMVDGFEGEKGAVVAGSRGYFLKGVLVFLEQALIQYALRTLGS 242
Query: 210 KGFTPVIPPYMVRRFVEEGSTTFEDFEDVIYKVEG-----------EDLYLIPTAEHPLA 258
+G+ P+ P+ +R+ V + F++ +YKV G ++ YLI T+E P+A
Sbjct: 243 RGYIPIYTPFFMRKEVMQEVAQLSQFDEELYKVIGKGSEKSDDNSYDEKYLIATSEQPIA 302
Query: 259 GMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKGIFRVHQFHKVEQFVYSRPEE--S 316
+H +E L +DLP+ Y G+S CFR+E G+ G+DT+GIFRVHQF K+EQFVYS P + S
Sbjct: 303 ALHRDEWLRPEDLPIKYAGLSTCFRQEVGSHGRDTRGIFRVHQFEKIEQFVYSSPHDNKS 362
Query: 317 WEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKYDIEAWMPGQGRFREVVSASN 376
WE E +I AEE +Q L IPY +VNI +G L + A+KK D+EAW PG G FRE+VS SN
Sbjct: 363 WEMFEEMITTAEEFYQSLGIPYHIVNIVSGSLNHAASKKLDLEAWFPGSGAFRELVSCSN 422
Query: 377 CTDWQARRLNIRF--RDRTDEKPRYVHTLNSTAIATSRAIVAILENHQEEDGTVKIPKVL 434
CTD+QARRL IR+ + +K +VH LN+T AT+R I AILEN+Q E G + +P+ L
Sbjct: 423 CTDYQARRLRIRYGQTKKMMDKVEFVHMLNATMCATTRTICAILENYQTEKG-ITVPEKL 481
Query: 435 WKY--TGFKEIVPVEK 448
++ G +E++P K
Sbjct: 482 KEFMPPGLQELIPFVK 497
>gb|AAC17621.1| (AC002131) Similar to seryl-tRNA synthetase gb|U10400 from S
cerevisiae. EST gb|N96627 comes from this gene.
[Arabidopsis thaliana]
Length = 573
Score = 301 bits (763), Expect = 1e-80
Identities = 175/464 (37%), Positives = 276/464 (58%), Gaps = 23/464 (4%)
Query: 2 LDIKLIRENPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIEI 61
+D K IR+N E V+ +++ R + + +L+L KE+ +LR ERN +A ++
Sbjct: 77 IDFKWIRDNKEAVEINIRNRNSNANL---EAVLQLYENMVNLQKEVERLREERNNVAKKM 133
Query: 62 GKRRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGESEE 121
+ + E E L+ + K + + + +LE+++ +LK ++ + +PN+THP VP+G +
Sbjct: 134 KGKLEPSER-ERLVEEGKNLKESLVTLEEDLVKLKDELQHVAQSIPNMTHPDVPVGGEDS 192
Query: 122 DNV--PIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARAAK 179
+ + ++ + + E L G + K H+ L + L DF AA+
Sbjct: 193 SAIRQEVSYFCQNSLNSCVDEGILLSKVGSPRE--FSFPIKDHLQLGKDLDLIDFDSAAE 250
Query: 180 VSGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEGSTTFEDFED-- 237
VSGS+F+YL NE V+L++AL+ + L +++KKG+TP+ P +VR + E F+ D
Sbjct: 251 VSGSKFFYLKNEAVLLEMALLNWTLSQVMKKGYTPLTTPEIVRSSIVE-KCGFQPRGDNT 309
Query: 238 VIYKVEGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKGIF 297
+Y ++G D LI TAE P+ G+H + IL LPL Y+ S CFR EAG AG TKG++
Sbjct: 310 QVYSIDGTDQCLIGTAEIPVGGIHMDSILLESALPLKYIAFSHCFRTEAGAAGAATKGLY 369
Query: 298 RVHQFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKYD 357
RVHQF K E FV +PE+S +H+ +I+ E+LF L + ++ +++ T DLG A +K+D
Sbjct: 370 RVHQFSKAEMFVICQPEDSESFHQELIQIEEDLFTSLGLHFKTLDMATADLGAPAYRKFD 429
Query: 358 IEAWMPGQGRFREVVSASNCTDWQARRLNIRFR----DRTDEK--------PRYVHTLNS 405
IEAWMPG GRF E+ SASNCTD+Q+RRL IR+R +T K ++VHTLN+
Sbjct: 430 IEAWMPGLGRFGEISSASNCTDYQSRRLGIRYRPSEPPQTGPKKGKANLPATKFVHTLNA 489
Query: 406 TAIATSRAIVAILENHQEEDGTVKIPKVLWKYTGFKEIVPVEKK 449
TA A R +V +LEN+Q+EDG+V IP+ L + G E++ + K
Sbjct: 490 TACAVPRMMVCLLENYQQEDGSVVIPEPLRPFMGGIELIKPKHK 533
>gi|5730029 seryl-tRNA synthetase [Homo sapiens]
>gi|1351173|sp|P49591|SYS_HUMAN SERYL-TRNA SYNTHETASE
(SERINE--TRNA LIGASE) (SERRS) >gi|7437671|pir||G01026
serine--tRNA ligase (EC 6.1.1.11) - human
>gi|1050527|emb|CAA62635.1| (X91257) seryl-tRNA
synthetase [Homo sapiens]
Length = 514
Score = 301 bits (762), Expect = 1e-80
Identities = 186/496 (37%), Positives = 277/496 (55%), Gaps = 73/496 (14%)
Query: 1 MLDIKLIREN----PELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNK 56
+LD+ L R + P L++ +KR + + +D+++K D+EWR + L +N
Sbjct: 2 VLDLDLFRVDKGGDPALIRETQEKRFKDPGL--VDQLVKADSEWRRCRFRADNLSKLKNL 59
Query: 57 IAIEIGKRRKKGEPV-----------------EELLAKSK-EIVKRIESLEKEV------ 92
+ IG++ KK EPV + LA K +K++ L E
Sbjct: 60 CSKTIGEKMKKKEPVGDDESVPENVLSFDDLTADALANLKVSQIKKVRLLIDEAILKCDA 119
Query: 93 EELKKKIDYY--LWRLPNITHPSVPIGESEE-DNVPIRFWGKARVWEGHLERFLEQSQGK 149
E +K + + + L + N+ HPSVPI E+ DN R WG V +
Sbjct: 120 ERIKLEAERFENLREIGNLLHPSVPISNDEDVDNKVERIWGDCTV--------------R 165
Query: 150 MEYEVLEWRPKLHVDLLEILGGADFARAAKVSGSRFYYLLNEIVILDLALIRFALDELIK 209
+Y HVDL+ ++ G + + A V+GSR Y+L +V L+ ALI++AL L
Sbjct: 166 KKYS--------HVDLVVMVDGFEGEKGAVVAGSRGYFLKGVLVFLEQALIQYALRTLGS 217
Query: 210 KGFTPVIPPYMVRRFVEEGSTTFEDFEDVIYKVEG-----------EDLYLIPTAEHPLA 258
+G+ P+ P+ +R+ V + F++ +YKV G ++ YLI T+E P+A
Sbjct: 218 RGYIPIYTPFFMRKEVMQEVAQLSQFDEELYKVIGKGSEKSDDNSYDEKYLIATSEQPIA 277
Query: 259 GMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKGIFRVHQFHKVEQFVYSRPEE--S 316
+H +E L +DLP+ Y G+S CFR+E G+ G+DT+GIFRVHQF K+EQFVYS P + S
Sbjct: 278 ALHRDEWLRPEDLPIKYAGLSTCFRQEVGSHGRDTRGIFRVHQFEKIEQFVYSSPHDNKS 337
Query: 317 WEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKYDIEAWMPGQGRFREVVSASN 376
WE E +I AEE +Q L IPY +VNI +G L + A+KK D+EAW PG G FRE+VS SN
Sbjct: 338 WEMFEEMITTAEEFYQSLGIPYHIVNIVSGSLNHAASKKLDLEAWFPGSGAFRELVSCSN 397
Query: 377 CTDWQARRLNIRF--RDRTDEKPRYVHTLNSTAIATSRAIVAILENHQEEDGTVKIPKVL 434
CTD+QARRL IR+ + +K +VH LN+T AT+R I AILEN+Q E G + +P+ L
Sbjct: 398 CTDYQARRLRIRYGQTKKMMDKVEFVHMLNATMCATTRTICAILENYQTEKG-ITVPEKL 456
Query: 435 WKY--TGFKEIVPVEK 448
++ G +E++P K
Sbjct: 457 KEFMPPGLQELIPFVK 472
>gb|AAG02209.1|AF290915_1 (AF290915) seryl-tRNA synthetase [Candida albicans]
Length = 462
Score = 299 bits (757), Expect = 5e-80
Identities = 185/464 (39%), Positives = 271/464 (57%), Gaps = 32/464 (6%)
Query: 1 MLDIK--LIRE--NPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNK 56
MLDI L+ + +PE++K KKRG+ ++ +DEI+ EW ++++ + N
Sbjct: 1 MLDINAFLVEKGGDPEIIKASQKKRGD--SVELVDEIIAEYKEWVKLRFDLDEHNKKLNS 58
Query: 57 IAIEIGKRRKKGEPVEELLAKSKEIV-KRIESLEKEVE---ELKKKIDYYLWRLPNITHP 112
+ EIGKR K E ++L+A+ +++ ++ E +EKE E L+ KI+ ++ NI H
Sbjct: 59 VQKEIGKRFKAKEDAKDLIAEKEKLSNEKKEIIEKEAEADKNLRSKIN----QVGNIVHE 114
Query: 113 SVPIGESEEDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGA 172
SV + EE+N +R W + + K+ H ++L L G
Sbjct: 115 SVVDSQDEENNELVRTWTPENYKKPEQIAAATGAPAKLS----------HHEVLLRLDGY 164
Query: 173 DFARAAKVSGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEGSTTF 232
D R ++ G R Y+L N V L+ ALI + L L KG+ P+ P M+ + V +
Sbjct: 165 DPERGVRIVGHRGYFLRNYGVFLNQALINYGLSFLSSKGYVPLQAPVMMNKEVMAKTAQL 224
Query: 233 EDFEDVIYKV-EGED-LYLIPTAEHPLAGMHANEILDG--KDLPLLYVGISPCFRKEAGT 288
F++ +YKV +GED YLI T+E P++ HA E + + LP+ Y G S CFR+EAG+
Sbjct: 225 SQFDEELYKVIDGEDEKYLIATSEQPISAYHAGEWFESPAEQLPVRYAGYSSCFRREAGS 284
Query: 289 AGKDTKGIFRVHQFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDL 348
GKD GIFRVH F K+EQFV + PE+SWE +R+I +EE +Q L +PYRVV I +G+L
Sbjct: 285 HGKDAWGIFRVHAFEKIEQFVLTEPEKSWEEFDRMIGCSEEFYQSLGLPYRVVGIVSGEL 344
Query: 349 GYVAAKKYDIEAWMPGQGRFREVVSASNCTDWQARRLNIR--FRDRTDEKPRYVHTLNST 406
AAKKYD+EAW P Q ++E+VS SNCTD+Q+R L IR + + ++ +YVH LNST
Sbjct: 345 NNAAAKKYDLEAWFPFQQEYKELVSCSNCTDYQSRNLEIRCGIKQQNQQEKKYVHCLNST 404
Query: 407 AIATSRAIVAILENHQEEDGTVKIPKVLWKY-TGFKEIVPVEKK 449
AT R I ILEN+Q+EDG V IP+VL KY G E +P K+
Sbjct: 405 LSATERTICCILENYQKEDGLV-IPEVLRKYIPGEPEFIPYIKE 447
>sp|O83653|SYS_TREPA SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) (SERRS)
>gi|7437680|pir||F71299 serine--tRNA ligase (EC
6.1.1.11) (serS) - syphilis spirochete
>gi|3322945|gb|AAC65620.1| (AE001239) seryl-tRNA
synthetase (serS) [Treponema pallidum]
Length = 426
Score = 298 bits (756), Expect = 7e-80
Identities = 176/452 (38%), Positives = 253/452 (55%), Gaps = 36/452 (7%)
Query: 1 MLDIKLIRENPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIE 60
MLD + IREN + VK ++K R + I + + A+L+E+ + R+E +
Sbjct: 1 MLDYRFIRENVDAVKENVKVRNVHADVDAIVHLYDQRVKLLAELQELQRARNENAQTMKS 60
Query: 61 IGKRRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGESE 120
+ VE + + RI E+ + ++ ++ LPN+TH P G S+
Sbjct: 61 SLDALARSACVET----GRALKDRIAHSERLLVQISDQLLSATQALPNMTHMCTPHGRSD 116
Query: 121 EDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARAAKV 180
DN+ I+ G + + P+ HV+L +L DF KV
Sbjct: 117 SDNLEIKRCGVPPCFS--------------------FSPRDHVELARLLDIVDFEAGKKV 156
Query: 181 SGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEGSTTFEDFE---- 236
SG +FYYL E V+L+ ALI F L L ++GF P + P + R EG F
Sbjct: 157 SGIKFYYLKREGVLLEQALIMFGLQFLQERGFVPFLTPDIAR----EGMVCGLGFNPRGS 212
Query: 237 -DVIYKVEGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKG 295
IY++EGE L+ TAE L HA E+L+ + LP LY G+S CFRKEAG AG+ ++G
Sbjct: 213 GSNIYRIEGEHRCLVATAEITLGAYHAGEVLEERSLPRLYAGLSHCFRKEAGAAGQFSRG 272
Query: 296 IFRVHQFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKK 355
++RVHQF K+E F Y P +S HER+ EE+F LEIP+RVV +C GDLG A +K
Sbjct: 273 LYRVHQFTKLEMFAYCTPSDSECLHERLRSLEEEIFTALEIPFRVVEVCAGDLGAPAYRK 332
Query: 356 YDIEAWMPGQ--GRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRA 413
+D+EAWMPG+ G + EV SASNCTD+QARRLN+R++D + K YVH LN TA+A SR
Sbjct: 333 WDLEAWMPGRQGGSWGEVTSASNCTDYQARRLNVRYKD-AEGKKHYVHMLNGTALAISRV 391
Query: 414 IVAILENHQEEDGTVKIPKVLWKYTGFKEIVP 445
++A+LEN Q+ +G V+IP+ L + GF+ + P
Sbjct: 392 LIALLENGQDAEGRVRIPQALVPFCGFEYLYP 423
>gi|6320226 seryl-tRNA synthetase; Ses1p [Saccharomyces cerevisiae]
>gi|1711650|sp|P07284|SYSC_YEAST SERYL-TRNA SYNTHETASE,
CYTOPLASMIC (SERINE--TRNA LIGASE) (SERRS)
>gi|1070526|pir||YSBYC serine--tRNA ligase (EC
6.1.1.11), cytosolic - yeast (Saccharomyces cerevisiae)
>gi|642295|emb|CAA87802.1| (Z47814) Ses1p [Saccharomyces
cerevisiae] >gi|1216231|emb|CAA65216.1| (X95966)
seryl-tRNA synthetase [Saccharomyces cerevisiae]
>gi|1431454|emb|CAA98844.1| (Z74319) ORF YDR023w
[Saccharomyces cerevisiae]
Length = 462
Score = 298 bits (756), Expect = 7e-80
Identities = 175/456 (38%), Positives = 266/456 (57%), Gaps = 24/456 (5%)
Query: 1 MLDIKLIRE----NPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNK 56
MLDI E NPEL++ K R +I +DEI+ +W E+++L + NK
Sbjct: 1 MLDINQFIEDKGGNPELIRQSQKARNASVEI--VDEIISDYKDWVKTRFELDELNKKFNK 58
Query: 57 IAIEIGKRRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPI 116
+ +IG + K E LLA+ +++ ++ + L ++ ++ K + ++++ NI HPSV +
Sbjct: 59 LQKDIGLKFKNKEDASGLLAEKEKLTQQKKELTEKEQQEDKDLKKKVFQVGNIVHPSVVV 118
Query: 117 GESEEDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFAR 176
EE+N +R W + ++ G + + H ++L L G D R
Sbjct: 119 SNDEENNELVRTWKPEDL----------EAVGPIASVTGKPASLSHHEILLRLDGYDPDR 168
Query: 177 AAKVSGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEGSTTFEDFE 236
K+ G R Y+ N V L+ ALI + L L KG+ P+ P M+ + + + +F+
Sbjct: 169 GVKICGHRGYFFRNYGVFLNQALINYGLQFLAAKGYIPLQAPVMMNKELMSKTAQLSEFD 228
Query: 237 DVIYKV-EGED-LYLIPTAEHPLAGMHANEILDG--KDLPLLYVGISPCFRKEAGTAGKD 292
+ +YKV +GED YLI T+E P++ H+ E + + LP+ YVG S CFR+EAG+ GKD
Sbjct: 229 EELYKVIDGEDEKYLIATSEQPISAYHSGEWFEKPQEQLPIHYVGYSSCFRREAGSHGKD 288
Query: 293 TKGIFRVHQFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVA 352
G+FRVH F K+EQFV + PE+SWE E++I +EE ++ L++PYR+V I +G+L A
Sbjct: 289 AWGVFRVHAFEKIEQFVITEPEKSWEEFEKMISYSEEFYKSLKLPYRIVGIVSGELNNAA 348
Query: 353 AKKYDIEAWMPGQGRFREVVSASNCTDWQARRLNIR--FRDRTDEKPRYVHTLNSTAIAT 410
AKKYD+EAW P Q ++E+VS SNCTD+Q+R L IR + D + +YVH LNST AT
Sbjct: 349 AKKYDLEAWFPYQKEYKELVSCSNCTDYQSRNLEIRCGIKKMGDREKKYVHCLNSTLAAT 408
Query: 411 SRAIVAILENHQEEDGTVKIPKVLWKY-TGFKEIVP 445
RA+ ILEN+Q EDG V +P+VL KY G E +P
Sbjct: 409 QRALCCILENYQTEDGLV-VPEVLRKYIPGEPEFLP 443
>emb|CAA28572.1| (X04884) seryl-tRNA synthetase [Saccharomyces cerevisiae]
Length = 462
Score = 297 bits (752), Expect = 2e-79
Identities = 175/456 (38%), Positives = 266/456 (57%), Gaps = 24/456 (5%)
Query: 1 MLDIKLIRE----NPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNK 56
MLDI E NPEL++ K R +I +DEI+ +W E+++L + NK
Sbjct: 1 MLDINQFIEDKGGNPELIRQSQKARNASVEI--VDEIISDYKDWVKTRFELDELNKKFNK 58
Query: 57 IAIEIGKRRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPI 116
+ +IG + K E LLA+ +++ ++ + L ++ ++ K + ++++ NI HPSV +
Sbjct: 59 LQKDIGLKFKNKEDASGLLAEKEKLTQQKKELTEKEQQEDKDLKKKVFQVGNIVHPSVVV 118
Query: 117 GESEEDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFAR 176
EE+N +R W + ++ G + + H ++L L G D R
Sbjct: 119 SNDEENNELVRTWKPEDL----------EAVGPIASVTGKPASLSHHEILLRLDGYDPDR 168
Query: 177 AAKVSGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEGSTTFEDFE 236
K+ G R Y+ N V L+ ALI + L L KG+ P+ P M+ + + + +F+
Sbjct: 169 GVKICGHRGYFFRNYGVFLNQALINYGLQFLAAKGYIPLQAPVMMNKELMSKTAQPSEFD 228
Query: 237 DVIYKV-EGED-LYLIPTAEHPLAGMHANEILDG--KDLPLLYVGISPCFRKEAGTAGKD 292
+ +YKV +GED YLI T+E P++ H+ E + + LP+ YVG S CFR+EAG+ GKD
Sbjct: 229 EELYKVIDGEDEKYLIATSEQPISAYHSGEWFEKPQEQLPIHYVGYSSCFRREAGSHGKD 288
Query: 293 TKGIFRVHQFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVA 352
G+FRVH F K+EQFV + PE+SWE E++I +EE ++ L++PYR+V I +G+L A
Sbjct: 289 AWGVFRVHAFEKIEQFVITEPEKSWEEFEKMISYSEEFYKSLKLPYRIVGIVSGELNNAA 348
Query: 353 AKKYDIEAWMPGQGRFREVVSASNCTDWQARRLNIR--FRDRTDEKPRYVHTLNSTAIAT 410
AKKYD+EAW P Q ++E+VS SNCTD+Q+R L IR + D + +YVH LNST AT
Sbjct: 349 AKKYDLEAWFPYQKEYKELVSCSNCTDYQSRNLEIRCGIKKMGDREKKYVHCLNSTLAAT 408
Query: 411 SRAIVAILENHQEEDGTVKIPKVLWKY-TGFKEIVP 445
RA+ ILEN+Q EDG V +P+VL KY G E +P
Sbjct: 409 QRALCCILENYQTEDGLV-VPEVLRKYIPGEPEFLP 443
>sp|P39919|SYS_COXBU SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) (SERRS)
>gi|1084147|pir||S43135 serine--tRNA ligase (EC
6.1.1.11) - Coxiella burnetii >gi|468532|emb|CAA53292.1|
(X75627) serine--tRNA ligase [Coxiella burnetii]
Length = 423
Score = 291 bits (737), Expect = 1e-77
Identities = 163/442 (36%), Positives = 247/442 (55%), Gaps = 27/442 (6%)
Query: 1 MLDIKLIRENPELVKNDLKKRG-ELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAI 59
MLD K++R+N E V L++RG E++ D L+L+ + + I + +RN+++
Sbjct: 1 MLDPKILRQNLEHVVEKLRRRGFEMDS----DTFLQLENKRKEAQLAIQSFQTKRNQLSK 56
Query: 60 EIGKRRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGES 119
IG + KGE E L+A+ ++ ++ E E ++K + +PN+ H SVP G+S
Sbjct: 57 TIGMAKSKGENPELLMAEVSQLNDELKQEEANFETIQKAFSDFQLAIPNLPHDSVPDGKS 116
Query: 120 EEDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARAAK 179
E DN IR WG ++ + PK H L E DF AAK
Sbjct: 117 ENDNREIRQWGAPPGFD--------------------FTPKDHTVLGERDNQLDFEAAAK 156
Query: 180 VSGSRFYYLLNEIVILDLALIRFALD-ELIKKGFTPVIPPYMVRRFVEEGSTTFEDFEDV 238
+SG+RF L + AL +F LD + G+ V PY+V G+ F +
Sbjct: 157 LSGARFVVLRGSLARAHRALAQFMLDLHTDQHGYEEVYVPYLVHEECLYGTGQLPKFREE 216
Query: 239 IYKVEGE-DLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKGIF 297
++V G+ + +L+PT E PL + +EI++ LP +V +PCFR EAG+ GKD +G+
Sbjct: 217 QFQVAGDRNFFLVPTGEVPLVNLARDEIIEAPALPKKWVAQTPCFRSEAGSYGKDVRGMI 276
Query: 298 RVHQFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKYD 357
R HQF KVE +PE S++ E I R AE++ Q L +PYRVV +C GDLG+ AAK YD
Sbjct: 277 RQHQFQKVELVQLVQPENSYQALEEITRQAEKVLQLLALPYRVVELCAGDLGFAAAKTYD 336
Query: 358 IEAWMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIVAI 417
+E W+P Q ++RE+ S SNC D+QARR+ R+R+ KP +HTLN + +A R +VA+
Sbjct: 337 LEVWLPSQNKYREISSCSNCEDFQARRIQARWRNPKTGKPELLHTLNGSGLAVGRTLVAV 396
Query: 418 LENHQEEDGTVKIPKVLWKYTG 439
+EN+Q+ DG +++P L Y G
Sbjct: 397 MENYQQADGHIRVPDALKSYMG 418
>pir||D82932 seryl-tRNA synthetase UU106 [imported] - Ureaplasma urealyticum
>gi|6899062|gb|AAF30512.1|AE002111_1 (AE002111)
seryl-tRNA synthetase [Ureaplasma urealyticum]
Length = 418
Score = 289 bits (733), Expect = 3e-77
Identities = 160/438 (36%), Positives = 245/438 (55%), Gaps = 23/438 (5%)
Query: 1 MLDIKLIRENPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIE 60
M DI LIR++ K + + + D+I LD R+ +++ L ++N+++ E
Sbjct: 1 MFDINLIRKDIATTKEKMLNKKVPSNL--FDQIFDLDVLVRSLMQQEQNLNAKKNQLSKE 58
Query: 61 IGKRRKKGEP-VEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGES 119
IG K +P +++ L I ++ + + + +++ L +PN+ SVPIG
Sbjct: 59 IGILAKNKDPKLQQTLDLVNNIKNELQDISLTLSNKQDELNKLLLVIPNMPDDSVPIGND 118
Query: 120 EEDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARAAK 179
E DNV I+ K + ++ + P H DL DF ++ K
Sbjct: 119 ENDNVEIKKVFKPKKFD--------------------FLPLAHWDLAVKNKLIDFDKSTK 158
Query: 180 VSGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEGSTTFEDFEDVI 239
++GSRF N L AL +F LD +K GF+ + P +V + GS F D +
Sbjct: 159 ITGSRFIIYTNFGARLYRALQQFCLDMNVKAGFSEIWAPVIVNQESLIGSGNLPKFADDL 218
Query: 240 YKVEGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKGIFRV 299
+K+E + YL PTAE L +H NEIL DLPL Y ++PCFR EAG+AG+D +G+ R
Sbjct: 219 FKLENSNYYLSPTAEVQLTNLHRNEILKASDLPLYYTALTPCFRSEAGSAGRDVRGVIRQ 278
Query: 300 HQFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKYDIE 359
HQFHKVE +PE+S++ E + R AE + + LE+PYR + +CTGDLG+ +AK YD+E
Sbjct: 279 HQFHKVELVKLCKPEDSFKELESMTRQAESILEALELPYRRIVLCTGDLGFSSAKTYDLE 338
Query: 360 AWMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIVAILE 419
W+P ++E+ S SNCT++QARR IR+++ D VHTLN +++A R AI+E
Sbjct: 339 VWLPSYNAYKEISSCSNCTNFQARRAKIRYKETIDATTELVHTLNGSSLAIDRLWAAIVE 398
Query: 420 NHQEEDGTVKIPKVLWKY 437
N+Q+EDG++ IPKVL KY
Sbjct: 399 NYQQEDGSINIPKVLKKY 416
>gb|AAG20222.1| (AE005098) serine-tRNA synthetase; SerS [Halobacterium sp. NRC-1]
Length = 474
Score = 289 bits (732), Expect = 4e-77
Identities = 168/456 (36%), Positives = 256/456 (55%), Gaps = 40/456 (8%)
Query: 1 MLDIKLIRENPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIE 60
ML + +RE+PE V++ L +G + D IL++D EWR ++LRH+RN+++ +
Sbjct: 15 MLSRQFVREHPEKVRDALDAKGVDADL---DRILEVDEEWRELKARGDELRHDRNEVSSK 71
Query: 61 IGKRRKKGEP--VEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGE 118
IG+ ++ G+ +E + +S+ + + +E ++L+ +++ L LP + P+G+
Sbjct: 72 IGELKQAGDEDAAQEAIERSQALKDELADVEARADDLEAELERLLLTLPMVPDEDAPVGD 131
Query: 119 SEEDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARAA 178
SE +NV R +G + L H DL E L DF R A
Sbjct: 132 SEAENVERR------------------REGFDDRRDLPESVVPHYDLGEELDILDFERGA 173
Query: 179 KVSGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEGSTTFEDFEDV 238
KVSG FY+ L+ AL++F LD ++G+ V PP V EG+ F F +
Sbjct: 174 KVSGGGFYFSKGAGARLEHALVQFMLDVHREQGYEDVFPPMPVSARSMEGTGQFPKFVED 233
Query: 239 IYKVEGE--------DLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAG 290
Y++ GE DL+L+PTAE P+ M+ +EIL DLP+ + SP FR+EAG G
Sbjct: 234 AYRIGGENDADYDDDDLWLLPTAEVPVTNMYRDEILLDDDLPVKHQAYSPNFRREAGEHG 293
Query: 291 KDTKGIFRVHQFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGY 350
+T+GI RVHQF+KVE + RPE+S E ++ AE + ++L++PYRV+ +CTGD+G+
Sbjct: 294 TETRGIVRVHQFNKVELVNFVRPEDSAERFHGLLDEAEAVLRRLDLPYRVLEMCTGDMGF 353
Query: 351 VAAKKYDIEAWMPGQ---------GRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVH 401
AKKYDIE W PG GR+ EV S SN D+QARR +I++R E ++H
Sbjct: 354 TQAKKYDIEVWAPGDDMDGGPEMGGRWLEVSSVSNFKDFQARRADIQYRPERHESAEHLH 413
Query: 402 TLNSTAIATSRAIVAILENHQEEDGTVKIPKVLWKY 437
TLN + +A R +VAILE +Q +DGTV +P+ L Y
Sbjct: 414 TLNGSGVAVPRVLVAILEYYQNDDGTVTVPEALQPY 449
>pir||E81053 seryl-tRNA synthetase NMB1684 [imported] - Neisseria meningitidis
(group B strain MD58) >gi|7226938|gb|AAF42032.1|
(AE002519) seryl-tRNA synthetase [Neisseria meningitidis
MC58]
Length = 431
Score = 289 bits (732), Expect = 4e-77
Identities = 174/448 (38%), Positives = 252/448 (55%), Gaps = 34/448 (7%)
Query: 1 MLDIKLIRENPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIE 60
MLDI+L+R N V L +RG D + + + K +E L+ RN I+ +
Sbjct: 1 MLDIQLLRSNTAAVAERLARRGYDFDTARFDTLEERRKSVQVKTEE---LQASRNSISKQ 57
Query: 61 IGKRRKKGEPVEELLAKSK--EIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGE 118
IG + +G+ E A ++ +I +E +++ ++K++D +L +PN+ H SVP G+
Sbjct: 58 IGALKGQGKHEEAQAAMNQVAQIKTDLEQAAADLDAVQKELDAWLLSIPNLPHESVPAGK 117
Query: 119 SEEDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARAA 178
E +NV +R G R + ++E+ K HVDL E LG DF A
Sbjct: 118 DETENVEVRKVGTPR---------------EFDFEI-----KDHVDLGEPLG-LDFEGGA 156
Query: 179 KVSGSRFYYLLNEIVILDLALIRFALD-ELIKKGFTPVIPPYMVRRFVEEGSTTFEDF-E 236
K+SG+RF + +I L AL +F LD ++ G+T PY+V +G+ F E
Sbjct: 157 KLSGARFTVMRGQIARLHRALAQFMLDTHTLQHGYTEHYTPYIVDDTTLQGTGQLPKFAE 216
Query: 237 DVIYKVEGED-----LYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGK 291
D+ + G D YLIPTAE L A+ I+ + LPL SPCFR EAG+ GK
Sbjct: 217 DLFHVTRGGDETKTTQYLIPTAEVTLTNTVADSIIPSEQLPLKLTAHSPCFRSEAGSYGK 276
Query: 292 DTKGIFRVHQFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYV 351
DT+G+ R HQF KVE PE+S+E E ++ +AE + + LE+PYRV+ +CTGD+G+
Sbjct: 277 DTRGLIRQHQFDKVEMVQIVHPEKSYETLEEMVGHAENILKALELPYRVITLCTGDMGFG 336
Query: 352 AAKKYDIEAWMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATS 411
AAK YD+E W+P Q +RE+ S SNC D+QARRL RF+D + K R VHTLN + +A
Sbjct: 337 AAKTYDLEVWVPAQNTYREISSCSNCEDFQARRLKARFKDE-NGKNRLVHTLNGSGLAVG 395
Query: 412 RAIVAILENHQEEDGTVKIPKVLWKYTG 439
R +VA+LENHQ DG++ IP L Y G
Sbjct: 396 RTLVAVLENHQNADGSINIPAALQPYMG 423
>sp|Q18678|SYS_CAEEL PROBABLE SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) (SERRS)
>gi|7497562|pir||T20008 hypothetical protein C47E12.1 -
Caenorhabditis elegans >gi|3875110|emb|CAA93105.1|
(Z68882) predicted using Genefinder~Similarity to Yeast
seryl-tRNA synthetase (SW:SYSC_YEAST), contains
similarity to Pfam domain: PF00587 (tRNA synthetase
class II (G, H, P, S and T)), Score=241.3,
E-value=4.5e-69, N=1~cDNA EST EMBL:M75770 comes from >
Length = 487
Score = 288 bits (729), Expect = 1e-76
Identities = 173/497 (34%), Positives = 272/497 (53%), Gaps = 75/497 (15%)
Query: 1 MLDIKLIRE----NPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNK 56
+LDI + R NPE+++ + R + K+ +DE+++LD +WR + ++L ++N
Sbjct: 2 VLDIDMFRTEKGGNPEIIRKSQQDRFKDPKL--VDEVIELDEKWRKERFVADQLNRQKNA 59
Query: 57 IAIEIGKRRKKGEPVEELLAKSKEIVKRIESLE---------KEVEELKKKIDYY----- 102
I+ IG++ KK EP + + +IV R+ L+ ++++L+ +D
Sbjct: 60 ISKAIGEKMKKKEPQGTDDSVADDIVARLAELKIDELSQLTVVQLKKLRVLVDEKSVQTA 119
Query: 103 -------------LWRLPNITHPSVPIGESEEDNVPIRFWGKARVWEGHLERFLEQSQGK 149
L ++ N+ H SV + + E +N +ER K
Sbjct: 120 AAVIANENARHEKLIQIGNLIHSSVVVSKDEANN--------------KIERTFGDLSTK 165
Query: 150 MEYEVLEWRPKLHVDLLEILGGADFARAAKVSGSRFYYLLNEIVILDLALIRFALDELIK 209
+Y HVDL+ ++ G D R V+G R Y+L +V L+ A+I+ AL L
Sbjct: 166 KKYS--------HVDLVVMVDGFDGERGTVVAGGRGYFLKGPLVFLEQAIIQLALQRLNV 217
Query: 210 KGFTPVIPPYMVRRFVEEGSTTFEDFEDVIYKVEG-----------EDLYLIPTAEHPLA 258
KG+ P+ P+ +R+ V + F+D +YKV ++ YLI T+E P+A
Sbjct: 218 KGYVPLYTPFFMRKEVMQEVAQLSQFDDELYKVSSKGSEIAGDTSVDEKYLIATSEQPIA 277
Query: 259 GMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKGIFRVHQFHKVEQFVYSRPE--ES 316
H NE + +LP+ Y G+S CFR+E G+ G+DT+GIFRVHQF K+EQFV P ES
Sbjct: 278 AYHRNEWIKETELPIKYAGVSTCFRQEVGSHGRDTRGIFRVHQFEKIEQFVLCSPNDNES 337
Query: 317 WEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKYDIEAWMPGQGRFREVVSASN 376
W + +I NAE +Q+L+IPY+VVNI +G+L AAKK+D+EAW PG G +RE+VS SN
Sbjct: 338 WTLFDEMIGNAESYYQELQIPYQVVNIVSGELNNAAAKKFDLEAWFPGSGAYRELVSCSN 397
Query: 377 CTDWQARRLNIRF---RDRTDEKPRYVHTLNSTAIATSRAIVAILENHQEEDGTVKIPKV 433
C D+Q+RRL +R+ + + E P +VH LN+T AT+R I AILEN+Q E+G + +P
Sbjct: 398 CLDYQSRRLKVRYGQTKKLSGEVP-FVHMLNATMCATTRVICAILENNQTEEG-INVPTA 455
Query: 434 L--WKYTGFKEIVPVEK 448
+ W ++ +P K
Sbjct: 456 IQQWMPENYRTFIPFVK 472
>pir||E81822 serine--tRNA ligase (EC 6.1.1.11) NMA1943 [imported] - Neisseria
meningitidis (group A strain Z2491)
>gi|7380575|emb|CAB85163.1| (AL162757) seryl-tRNA
synthetase [Neisseria meningitidis Z2491]
Length = 431
Score = 287 bits (727), Expect = 2e-76
Identities = 172/448 (38%), Positives = 249/448 (55%), Gaps = 34/448 (7%)
Query: 1 MLDIKLIRENPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIE 60
MLDI+L+R N V L +RG D + + + K +E L+ RN I+ +
Sbjct: 1 MLDIQLLRSNTAAVAERLARRGYDFDTARFDALEERRKSVQVKTEE---LQASRNSISKQ 57
Query: 61 IGKRRKKGEPVEELLAKSK--EIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGE 118
IG + +G+ E +A + +I +E +++ ++K++D +L +PN+ H VP G+
Sbjct: 58 IGALKGQGKHEEAQVAMDQVAQIKTDLEQAAADLDAVQKELDAWLLSIPNLPHEDVPFGK 117
Query: 119 SEEDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARAA 178
E +NV +R G R + ++E+ K HVDL E LG DF A
Sbjct: 118 DETENVEVRKVGTPR---------------EFDFEI-----KDHVDLGEPLG-LDFEGGA 156
Query: 179 KVSGSRFYYLLNEIVILDLALIRFALD-ELIKKGFTPVIPPYMVRRFVEEGSTTFEDF-E 236
K+SG+RF + +I L AL +F LD +K G+T PY+V +G+ F E
Sbjct: 157 KLSGARFTVMRGQIARLHRALAQFMLDTHTLKHGYTEHYTPYIVDDTTLQGTGQLPKFAE 216
Query: 237 DVIYKVEGED-----LYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGK 291
D+ + G D YLIPTAE L A I+ + LPL SPCFR EAG+ GK
Sbjct: 217 DLFHVTRGGDESKTTQYLIPTAEVTLTNTVAGSIIPSEQLPLKLTAHSPCFRSEAGSYGK 276
Query: 292 DTKGIFRVHQFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYV 351
DT+G+ R HQF KVE PE+S+E E ++ +AE + + LE+PYRV+ +CTGD+G+
Sbjct: 277 DTRGLIRQHQFDKVEMVQIVHPEKSYETLEEMVGHAENILKALELPYRVITLCTGDMGFG 336
Query: 352 AAKKYDIEAWMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATS 411
A K YD+E W+P Q +RE+ S SNC D+QARR+ RF+D + K R VHTLN + +A
Sbjct: 337 ATKTYDLEVWVPAQNTYREISSCSNCEDFQARRMKARFKDE-NGKNRLVHTLNGSGLAVG 395
Query: 412 RAIVAILENHQEEDGTVKIPKVLWKYTG 439
R +VA+LENHQ DG++ IP L Y G
Sbjct: 396 RTLVAVLENHQNADGSINIPAALQPYMG 423
>sp|P09156|SYS_ECOLI SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) (SERRS)
>gi|68545|pir||YSEC serine--tRNA ligase (EC 6.1.1.11) -
Escherichia coli >gi|42950|emb|CAA28673.1| (X05017)
seryl-tRNA synthetase [Escherichia coli]
>gi|1651420|dbj|BAA35625.1| (D90727) Serine-tRNA ligase
(EC 6.1.1.11) [Escherichia coli]
>gi|1787120|gb|AAC73979.1| (AE000191) serine tRNA
synthetase; also charges selenocystein tRNA with serine
[Escherichia coli K12]
Length = 430
Score = 279 bits (707), Expect = 4e-74
Identities = 157/453 (34%), Positives = 253/453 (55%), Gaps = 33/453 (7%)
Query: 1 MLDIKLIRENPELVKNDLKKRG-ELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAI 59
MLD L+R P+ V L +RG +L+ +D++ L+ + + L+ ERN +
Sbjct: 1 MLDPNLLRNEPDAVAEKLARRGFKLD----VDKLGALEERRKVLQVKTENLQAERNSRSK 56
Query: 60 EIGKRRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGES 119
IG+ + +GE +E L + ++ + +++ + E++ L+ +I +PN+ VP+G+
Sbjct: 57 SIGQAKARGEDIEPLRLEVNKLGEELDAAKAELDALQAEIRDIALTIPNLPADEVPVGKD 116
Query: 120 EEDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARAAK 179
E DNV + WG R + ++EV + HV L E+ G DFA A K
Sbjct: 117 ENDNVEVSRWGTPR---------------EFDFEVRD-----HVTLGEMHSGLDFAAAVK 156
Query: 180 VSGSRFYYLLNEIVILDLALIRFALD-ELIKKGFTPVIPPYMVRRFVEEGSTTFEDFEDV 238
++GSRF + +I + AL +F LD + G++ PY+V + G+ F
Sbjct: 157 LTGSRFVVMKGQIARMHRALSQFMLDLHTEQHGYSENYVPYLVNQDTLYGTGQLPKFAGD 216
Query: 239 IY-------KVEGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGK 291
++ + + + LIPTAE PL + EI+D DLP+ +PCFR EAG+ G+
Sbjct: 217 LFHTRPLEEEADTSNYALIPTAEVPLTNLVRGEIIDEDDLPIKMTAHTPCFRSEAGSYGR 276
Query: 292 DTKGIFRVHQFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYV 351
DT+G+ R+HQF KVE RPE+S E + +AE++ Q L +PYR + +CTGD+G+
Sbjct: 277 DTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLGLPYRKIILCTGDMGFG 336
Query: 352 AAKKYDIEAWMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATS 411
A K YD+E W+P Q +RE+ S SN D+QARR+ R R ++D+K R VHTLN + +A
Sbjct: 337 ACKTYDLEVWIPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSGLAVG 396
Query: 412 RAIVAILENHQEEDGTVKIPKVLWKYTGFKEIV 444
R +VA++EN+Q+ DG +++P+VL Y E +
Sbjct: 397 RTLVAVMENYQQADGRIEVPEVLRPYMNGLEYI 429
>sp|Q9Z736|SYS_CHLPN SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) (SERRS)
>gi|7437685|pir||F72026 serine--tRNA ligase (EC
6.1.1.11) 2 - Chlamydophila pneumoniae (strains CWL029
and AR39) >gi|4377187|gb|AAD19008.1| (AE001667) Seryl
tRNA Synthetase-2 [Chlamydophila pneumoniae CWL029]
>gi|7189912|gb|AAF38777.1| (AE002257) seryl-tRNA
synthetase [Chlamydophila pneumoniae AR39]
>gi|8979244|dbj|BAA99078.1| (AP002548) seryl tRNA
synthetase-2 [Chlamydophila pneumoniae J138]
Length = 427
Score = 279 bits (706), Expect = 5e-74
Identities = 162/446 (36%), Positives = 253/446 (56%), Gaps = 26/446 (5%)
Query: 1 MLDIKLIRENPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIE 60
MLDIK+IR+ PE + L+K+ KI ++ +L LD E R + L+ +R ++ +
Sbjct: 1 MLDIKIIRKTPEECETRLRKKDP--KIS-LEPVLSLDKEVRQLKTDSETLQAQRRLLSQD 57
Query: 61 IGKRRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGESE 120
I K + +G L+ + + + +E +E+ +++ ++ L LPN +P+ E +
Sbjct: 58 IHKAKTQGVDATNLIQEVETLAADLEKIEQHLDQKNAQLHELLSHLPNYPADDIPVSEDK 117
Query: 121 EDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARAAKV 180
N I+ G + + + PK H++L + L DF AAK
Sbjct: 118 AGNQVIKSVG--------------------DLPIFSFPPKHHLELNQELDILDFQAAAKT 157
Query: 181 SGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEGSTTFEDFEDVIY 240
+GS + N V+L+ AL+ + L + GF +PP +V++ + GS F+ Y
Sbjct: 158 TGSGWPAYKNRGVLLEWALLTYMLQKQAAHGFQLWLPPLLVKKEILFGSGQIPKFDGQYY 217
Query: 241 KVE-GED-LYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKGIFR 298
+VE GE LYLIPTAE L G + +IL K+LPL Y +PCFR+EAG AG +G+ R
Sbjct: 218 RVEDGEQYLYLIPTAEVVLNGFRSQDILTEKELPLYYAACTPCFRREAGAAGAQERGLVR 277
Query: 299 VHQFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKYDI 358
VHQFHKVE F ++ P + +E+++ EE+ +L++PYR+ + TGD+ + A+K D
Sbjct: 278 VHQFHKVEMFAFTTPNQDDIAYEKMLSIVEEMLTELKLPYRLSLLSTGDMSFTASKTIDA 337
Query: 359 EAWMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIVAIL 418
E W+PGQ F EV S S CTD+Q+RR R++D + K ++VHTLN + +AT R +VAIL
Sbjct: 338 EVWLPGQKAFYEVSSISQCTDFQSRRSGTRYKD-SQGKLQFVHTLNGSGLATPRLLVAIL 396
Query: 419 ENHQEEDGTVKIPKVLWKYTGFKEIV 444
EN+Q+ DG+V IP+VL Y G EI+
Sbjct: 397 ENNQQADGSVVIPEVLRPYLGGLEIL 422
>gb|AAF51155.1| (AE003581) CG17259 gene product [Drosophila melanogaster]
Length = 501
Score = 279 bits (706), Expect = 5e-74
Identities = 178/497 (35%), Positives = 265/497 (52%), Gaps = 74/497 (14%)
Query: 1 MLDIKLIRE----NPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNK 56
+LD+ L R NP+LV+ + KKR + + ++ ++ D EWR + L +N
Sbjct: 2 VLDLDLFRSDKGGNPDLVRENQKKR--FKDVALVETVIAKDTEWRQCRHRADNLNKVKNV 59
Query: 57 IAIEIGKRRKKGEPV---------------EELLAKSKE--IVKRIESL----------- 88
+ IG++ KK EPV E++A++ + V +I+ L
Sbjct: 60 CSKVIGEKMKKKEPVGAMSEDLPADVTKDLTEIVAETLQPLTVNQIKQLRVLIDDAMTEN 119
Query: 89 EKEVEELKKKIDYYLWRLPNITHPSVPIGESEEDNVPIRFWGKARVWEGHLERFLEQSQG 148
+K +E ++ + L + N H SVP+ E++N R +G + +G
Sbjct: 120 QKSLELAEQTRNTSLREVGNHLHESVPVSNDEDENRVERTFGDC------------EKRG 167
Query: 149 KMEYEVLEWRPKLHVDLLEILGGADFARAAKVSGSRFYYLLNEIVILDLALIRFALDELI 208
K HVDL+ ++ G + + A VSG R Y+L V L+ ALI+ AL L
Sbjct: 168 KYS----------HVDLIVMIDGMNAEKGAVVSGGRGYFLTGAAVFLEQALIQHALHLLY 217
Query: 209 KKGFTPVIPPYMVRRFVEEGSTTFEDFEDVIYKVEG-----------EDLYLIPTAEHPL 257
+ + P+ P+ +R+ V + F++ +YKV G ++ YLI T+E P+
Sbjct: 218 ARDYVPLYTPFFMRKEVMQEVAQLSQFDEELYKVVGKGSEKAEEVGIDEKYLIATSEQPI 277
Query: 258 AGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKGIFRVHQFHKVEQFVYSRPEE-- 315
A H +E L LP+ Y G+S CFR+E G+ G+DT+GIFRVHQF KVEQFV + P +
Sbjct: 278 AAYHRDEWLPESSLPIKYAGLSTCFRQEVGSHGRDTRGIFRVHQFEKVEQFVLTSPHDNK 337
Query: 316 SWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKYDIEAWMPGQGRFREVVSAS 375
SWE + +I NAE+ Q L IPYRVVNI +G L + A+KK D+EAW G G +RE+VS S
Sbjct: 338 SWEMMDEMIGNAEQFCQSLGIPYRVVNIVSGALNHAASKKLDLEAWFGGSGAYRELVSCS 397
Query: 376 NCTDWQARRLNIRF--RDRTDEKPRYVHTLNSTAIATSRAIVAILENHQEEDGTVKIPKV 433
NC D+QARRL +RF + + YVH LN+T A +R I AILE HQ E G +K+P+
Sbjct: 398 NCLDYQARRLLVRFGQTKKMNAAVDYVHMLNATMCAATRVICAILETHQTETG-IKVPEP 456
Query: 434 LWKY--TGFKEIVPVEK 448
L KY F++ +P K
Sbjct: 457 LKKYMPAKFQDEIPFVK 473
>pdb|1SES|A Chain A, Seryl-Trna Synthetase (E.C.6.1.1.11) (Serine-Trna Ligase)
Complexed With Seryl-Hydroxamate-Amp
>gi|576268|pdb|1SES|B Chain B, Seryl-Trna Synthetase
(E.C.6.1.1.11) (Serine-Trna Ligase) Complexed With
Seryl-Hydroxamate-Amp >gi|576269|pdb|1SET|A Chain A,
Seryl-Trna Synthetase (E.C.6.1.1.11) (Serine-Trna
Ligase) Complexed With
5'-O-[n-(L-Seryl)-Sulphamoyl]adenosine
>gi|576270|pdb|1SET|B Chain B, Seryl-Trna Synthetase
(E.C.6.1.1.11) (Serine-Trna Ligase) Complexed With
5'-O-[n-(L-Seryl)-Sulphamoyl]adenosine
>gi|494615|pdb|1SRY|A Chain A, Seryl-Trna Synthetase
(E.C.6.1.1.11) >gi|494616|pdb|1SRY|B Chain B, Seryl-Trna
Synthetase (E.C.6.1.1.11) >gi|515248|pdb|1SER|B Chain B,
Seryl-Trna Synthetase (E.C.6.1.1.11) Complexed With
Trna-Ser 2 (Gga Anticodon) >gi|515247|pdb|1SER|A Chain
A, Seryl-Trna Synthetase (E.C.6.1.1.11) Complexed With
Trna-Ser 2 (Gga Anticodon)
Length = 421
Score = 278 bits (703), Expect = 1e-73
Identities = 162/449 (36%), Positives = 260/449 (57%), Gaps = 34/449 (7%)
Query: 1 MLDIKLIRENPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIE 60
M+D+K +R+ PE+ ++++G + + +L LD E + K + +++ ERN++A
Sbjct: 1 MVDLKRLRQEPEVFHRAIREKGVALDL---EALLALDREVQELKKRLQEVQTERNQVA-- 55
Query: 61 IGKRRKKGEPVEE--LLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGE 118
KR K P E+ L+A+ K + + + LE+ + E + +++ L ++P P P+G
Sbjct: 56 --KRVPKAPPEEKEALIARGKALGEEAKRLEEALREKEARLEALLLQVPLPPWPGAPVGG 113
Query: 119 SEEDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARAA 178
E + R +++ G E+ + P HV L+E G + R +
Sbjct: 114 EEAN------------------REIKRVGGPPEFS---FPPLDHVALMEKNGWWE-PRIS 151
Query: 179 KVSGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEGSTTFEDFEDV 238
+VSGSR Y L ++ + +LAL+RFA+D + ++GF P+ P R G+ F + D
Sbjct: 152 QVSGSRSYALKGDLALYELALLRFAMDFMARRGFLPMTLPSYAREKAFLGTGHFPAYRDQ 211
Query: 239 IYKVEGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKGIFR 298
++ + DLYL TAE L +H+ EIL + LPL Y G +P FR EAG+ GKD +G+ R
Sbjct: 212 VWAIAETDLYLTGTAEVVLNALHSGEILPYEALPLRYAGYAPAFRSEAGSFGKDVRGLMR 271
Query: 299 VHQFHKVEQFVYSRP--EESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKY 356
VHQFHKVEQ+V + E S + ++ NAEE+ + LE+PYR+V + TGD+G ++
Sbjct: 272 VHQFHKVEQYVLTEASLEASDRAFQELLENAEEILRLLELPYRLVEVATGDMGPGKWRQV 331
Query: 357 DIEAWMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIVA 416
DIE ++P +GR+RE S S DWQARR N+R+RD + + RY +TLN+TA+AT R +
Sbjct: 332 DIEVYLPSEGRYRETHSCSALLDWQARRANLRYRD-PEGRVRYAYTLNNTALATPRILAM 390
Query: 417 ILENHQEEDGTVKIPKVLWKYTGFKEIVP 445
+LENHQ +DG V++P+ L Y G + + P
Sbjct: 391 LLENHQLQDGRVRVPQALIPYMGKEVLEP 419
>sp|P34945|SYS_THETH SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) (SERRS)
>gi|628482|pir||S38948 serine--tRNA ligase (EC 6.1.1.11)
- Thermus aquaticus
Length = 421
Score = 276 bits (698), Expect = 4e-73
Identities = 162/449 (36%), Positives = 259/449 (57%), Gaps = 34/449 (7%)
Query: 1 MLDIKLIRENPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIE 60
M+D+K +R+ PE+ ++++G + + +L LD E + K + +++ ERN++A
Sbjct: 1 MVDLKRLRQEPEVFHRAIREKGVALDL---EALLALDREVQELKKRLQEVQTERNQVA-- 55
Query: 61 IGKRRKKGEPVEE--LLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGE 118
KR K P E+ L+A+ K + + + LE+ + E + +++ L ++P P P+G
Sbjct: 56 --KRVPKAPPEEKEALIARGKALGEEAKRLEEALREKEARLEALLLQVPLPPWPGAPVGG 113
Query: 119 SEEDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARAA 178
E + R +++ G E+ + P HV L+E G + R +
Sbjct: 114 EEAN------------------REIKRVGGPPEFS---FPPLDHVALMEKNGWWE-PRIS 151
Query: 179 KVSGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEGSTTFEDFEDV 238
+VSGSR Y L ++ + +LAL+RFA+D + ++GF P+ P R G+ F D
Sbjct: 152 QVSGSRSYALKGDLALYELALLRFAMDFMARRGFLPMTLPSYAREKAFLGTGHFPATRDQ 211
Query: 239 IYKVEGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKGIFR 298
++ + DLYL TAE L +H+ EIL + LPL Y G +P FR EAG+ GKD +G+ R
Sbjct: 212 VWAIAETDLYLTGTAEVVLNALHSGEILPYEALPLRYAGYAPAFRSEAGSFGKDVRGLMR 271
Query: 299 VHQFHKVEQFVYSRP--EESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKY 356
VHQFHKVEQ+V + E S + ++ NAEE+ + LE+PYR+V + TGD+G ++
Sbjct: 272 VHQFHKVEQYVLTEASLEASDRAFQELLENAEEILRLLELPYRLVEVATGDMGPGKWRQV 331
Query: 357 DIEAWMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIVA 416
DIE ++P +GR+RE S S DWQARR N+R+RD + + RY +TLN+TA+AT R +
Sbjct: 332 DIEVYLPSEGRYRETHSCSALLDWQARRANLRYRD-PEGRVRYAYTLNNTALATPRILAM 390
Query: 417 ILENHQEEDGTVKIPKVLWKYTGFKEIVP 445
+LENHQ +DG V++P+ L Y G + + P
Sbjct: 391 LLENHQLQDGRVRVPQALIPYMGKEVLEP 419
>pir||C81382 serine--tRNA ligase (EC 6.1.1.11) Cj0389 [imported] - Campylobacter
jejuni (strain NCTC 11168) >gi|6967863|emb|CAB74225.1|
(AL139075) seryl-tRNA synthetase [Campylobacter jejuni]
Length = 411
Score = 273 bits (690), Expect = 4e-72
Identities = 162/437 (37%), Positives = 237/437 (54%), Gaps = 27/437 (6%)
Query: 1 MLDIKLIRENPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIE 60
MLD+K ++ N + V LK + K + ILK AE A LK+ E +
Sbjct: 1 MLDLKNLQNNFDEVAKKLKNK------KVDENILKKLAELFASLKKEKIALEEFQAFQNK 54
Query: 61 IGKRRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGESE 120
K E E L AK E +I +V L+ +++ +PNI VP+GE E
Sbjct: 55 FSKELATAEDKESLKAKLSENKSKINEQSAKVNALENELEEIAHAIPNIPDECVPVGEDE 114
Query: 121 EDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARAAKV 180
+NV L++ L ++ PK H +L E L DF R K+
Sbjct: 115 NENV-------------ELKKVLNPPS-------FDFTPKEHFELGESLNWLDFMRGVKI 154
Query: 181 SGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEGSTTFEDFEDVIY 240
S SRF L NE +L AL+ + +D +GF V P++V G+ F++ +Y
Sbjct: 155 SQSRFCVLKNEGALLSRALVNYMIDFNRSRGFEFVNVPFLVNGATMFGTGQLPKFKEDMY 214
Query: 241 KVEGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKGIFRVH 300
KV+ EDLYLI T+E P+ +++ EIL + LP+ S CFRKEAG+AG+DT+GI R H
Sbjct: 215 KVDDEDLYLISTSEIPVTNLYSGEILASETLPIKMTCYSACFRKEAGSAGRDTRGIIRQH 274
Query: 301 QFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKYDIEA 360
QF KVE ++PE+S ++ A +L L + +R + +CTGDLG+ AAK D+E
Sbjct: 275 QFEKVELVSITKPEQSDSVFNEMLECASDLLSSLGLAHRHLMLCTGDLGFSAAKTVDLEV 334
Query: 361 WMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIVAILEN 420
W+PGQ ++RE+ S SNC D+QARR IR+++ K VHTLN +++A R +VAI+EN
Sbjct: 335 WLPGQNKYREISSVSNCRDFQARRAKIRYKNE-QGKNELVHTLNGSSLAVGRTLVAIMEN 393
Query: 421 HQEEDGTVKIPKVLWKY 437
+Q+++G + IP VL KY
Sbjct: 394 YQDKEGKIHIPDVLKKY 410
>sp|P56458|SYS_HELPY SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) (SERRS)
>gi|7437677|pir||H64704 serine--tRNA ligase (EC
6.1.1.11) - Helicobacter pylori (strain 26695)
>gi|2314654|gb|AAD08517.1| (AE000647) seryl-tRNA
synthetase (serS) [Helicobacter pylori 26695]
Length = 415
Score = 272 bits (688), Expect = 6e-72
Identities = 155/442 (35%), Positives = 250/442 (56%), Gaps = 33/442 (7%)
Query: 1 MLDIKLIRENPELVKNDLKKRG-----ELEKIKWIDEILKLDAEWRAKLKEINKLRHERN 55
M+D KL+ ++ + V LKKR ELE+++ ++ ++ +L E+ L+ +N
Sbjct: 1 MIDRKLLLQDFDKVALSLKKRNNAMDDELERLR------EVITHYKKRLIELEGLQAFQN 54
Query: 56 KIAIEIGKRRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVP 115
K++ E G + + +L + + ++ L K V EL+++ID L +PN+ P
Sbjct: 55 KVSKEFGIKMAQKVDTSDLKKELENNKIKLNELSKSVGELEQQIDLKLSIIPNLVDEKTP 114
Query: 116 IGESEEDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFA 175
+G +EEDN+ I+ RV+ ++PK H +L + G DF
Sbjct: 115 LGTNEEDNIEIKKILTPRVFT--------------------FKPKEHFELAQQNGWIDFE 154
Query: 176 RAAKVSGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEGSTTFEDF 235
K++ SRF + + ALI LD K GF + P +V + G+ F
Sbjct: 155 SGVKLAKSRFSVIRGFGAKIYRALIHLMLDFNEKNGFEIIYTPALVNEKMLFGTGQLPKF 214
Query: 236 EDVIYKVEGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKG 295
++ ++K+E E+LYLIPTAE L ++ + I+ ++LP+ +PCFR EAG+AGKDT+G
Sbjct: 215 KEDVFKIENENLYLIPTAEVTLTNLYNDTIISVENLPIKMTAHTPCFRSEAGSAGKDTRG 274
Query: 296 IFRVHQFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKK 355
+ R HQF KVE + P+ES E ++ +A E+ + LE+P+R V +C+GDLG+ A+
Sbjct: 275 MIRQHQFDKVELVAITHPKESDVMQEHMLESASEILKALELPHRFVQLCSGDLGFSASNT 334
Query: 356 YDIEAWMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIV 415
DIE W+PGQ +RE+ S SN D+QARR IRF++ ++K + HTLN +++A R +V
Sbjct: 335 IDIEVWLPGQNCYREISSVSNTRDFQARRAKIRFKE--NQKNQLAHTLNGSSLAVGRTMV 392
Query: 416 AILENHQEEDGTVKIPKVLWKY 437
A++ENHQ+ DG++ IPK L KY
Sbjct: 393 ALMENHQQADGSIHIPKALEKY 414
>sp|Q9ZJD9|SYS_HELPJ SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) (SERRS)
>gi|7437676|pir||H71814 serine--tRNA ligase (EC
6.1.1.11) - Helicobacter pylori (strain J99)
>gi|4155982|gb|AAD06944.1| (AE001560) SERYL-TRNA
SYNTHETASE [Helicobacter pylori J99]
Length = 415
Score = 270 bits (683), Expect = 2e-71
Identities = 155/442 (35%), Positives = 249/442 (56%), Gaps = 33/442 (7%)
Query: 1 MLDIKLIRENPELVKNDLKKRG-----ELEKIKWIDEILKLDAEWRAKLKEINKLRHERN 55
M+D KL+ ++ + V LKKR ELE+++ + A ++ +L E+ L+ +N
Sbjct: 1 MIDRKLLLQDFDKVALSLKKRNHAMDDELERLR------EAIAHYKKQLIELEGLQAFQN 54
Query: 56 KIAIEIGKRRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVP 115
K++ E G + + +L + + ++ L K V E ++++D L +PN+ P
Sbjct: 55 KVSKEFGIKMAQKMDTSDLKKELENNKIKLNELSKSVGEAEQEMDLKLSIIPNLVDEKTP 114
Query: 116 IGESEEDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFA 175
+G SEEDN+ I+ + L ++PK H +L + G DF
Sbjct: 115 LGASEEDNIEIK-------------KILTPRN-------FTFKPKEHFELAQQNGWIDFE 154
Query: 176 RAAKVSGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEGSTTFEDF 235
K++ SRF + + ALI LD K GF + P +V + G+ F
Sbjct: 155 SGVKLAKSRFSVIRGFGAKIYRALIHLMLDFNEKNGFEIIYTPALVNEKMLFGTGQLPKF 214
Query: 236 EDVIYKVEGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKG 295
++ ++K+E E+LYLIPTAE L ++ + I+ ++LP+ +PCFR EAG+AGKDT+G
Sbjct: 215 KEDVFKIENENLYLIPTAEVTLTNLYNDTIISVENLPIKMTAHTPCFRSEAGSAGKDTRG 274
Query: 296 IFRVHQFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKK 355
+ R HQF KVE + P+ES E ++ +A E+ + LE+P+R V +C+GDLG+ A+
Sbjct: 275 MIRQHQFDKVELVAITHPKESDAMQEHMLESASEILKALELPHRFVQLCSGDLGFSASNT 334
Query: 356 YDIEAWMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIV 415
DIE W+PGQ +RE+ S SN D+QARR IRF++ ++K + VHTLN +++A R +V
Sbjct: 335 IDIEVWLPGQNCYREISSVSNTRDFQARRAKIRFKE--NQKNQLVHTLNGSSLAVGRTMV 392
Query: 416 AILENHQEEDGTVKIPKVLWKY 437
A++ENHQ+ DG++ IPK L KY
Sbjct: 393 ALMENHQQADGSIHIPKALEKY 414
>sp|O84734|SYS_CHLTR SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) (SERRS)
>gi|7437686|pir||D71479 serine--tRNA ligase (EC
6.1.1.11) - Chlamydia trachomatis (serotype D, strain
UW3/Cx) >gi|3329186|gb|AAC68324.1| (AE001343) Seryl tRNA
Synthetase [Chlamydia trachomatis]
Length = 428
Score = 269 bits (681), Expect = 4e-71
Identities = 159/446 (35%), Positives = 244/446 (54%), Gaps = 26/446 (5%)
Query: 1 MLDIKLIRENPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIE 60
MLDI+LIR+ P+ ++ L+K+ + + +L LD R + L +R ++ +
Sbjct: 1 MLDIRLIRKEPKECESRLQKKDPAISL---ERLLDLDKTVRQLKADSEALLAKRKVLSGQ 57
Query: 61 IGKRRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGESE 120
I K + E + L+ + I ++ + E ++E + ++ + RLPN VP+ +
Sbjct: 58 IHKAKVANENADALIQEVNTIADQLVAFETTLQEQEALLEDLMARLPNYPDEDVPVSPDK 117
Query: 121 EDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARAAKV 180
N I+ G E + PK H+ L E L DF AK
Sbjct: 118 TGNQVIK--------------------GHGEVPTFPFPPKHHMQLNEALQILDFKLPAKT 157
Query: 181 SGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEGSTTFEDFEDVIY 240
+GS + NE V+L+ AL+ + L++ GF +PP +V+R + GS F+ Y
Sbjct: 158 TGSGWPAYCNEGVLLEWALLTYLLNKQQAHGFQLWLPPLLVKRDILFGSGQIPKFDGQYY 217
Query: 241 KVEGED--LYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKGIFR 298
+VE D L+LIPTAE L G H+ EIL+ +DLPL Y +PCFR+EAG G +G+ R
Sbjct: 218 RVEDGDQSLFLIPTAEVVLNGFHSQEILNEQDLPLCYAAFTPCFRREAGAGGAHERGLVR 277
Query: 299 VHQFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKYDI 358
VHQFHKVE F ++ PE+ +++++ EE+ +L++PY++ + TGD+ + A K D
Sbjct: 278 VHQFHKVEMFAFTTPEQEEVVYQKMLHVVEEILSELQLPYQLSLLSTGDMSFTAKKTIDA 337
Query: 359 EAWMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIVAIL 418
E W+PGQ F EV S S C D+QARR R+RD K +V+TLN + +AT R +VAIL
Sbjct: 338 EVWLPGQKAFYEVSSISKCGDFQARRSETRYRD-AQGKLHFVNTLNGSGLATPRLLVAIL 396
Query: 419 ENHQEEDGTVKIPKVLWKYTGFKEIV 444
EN+Q+ DG+V IP VL Y +EI+
Sbjct: 397 ENYQQADGSVVIPSVLRPYMNNQEIL 422
>pir||A82242 seryl-tRNA synthetase VC1110 [imported] - Vibrio cholerae (group
O1 strain N16961) >gi|9655580|gb|AAF94269.1| (AE004191)
seryl-tRNA synthetase [Vibrio cholerae]
Length = 435
Score = 268 bits (679), Expect = 7e-71
Identities = 162/453 (35%), Positives = 250/453 (54%), Gaps = 38/453 (8%)
Query: 1 MLDIKLIRENPELVKNDLKKRG-ELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAI 59
MLD KL+R + L +RG +L+ ++ I L+ + ++ E+ L+ RN I+
Sbjct: 1 MLDSKLLRTELDETAAKLARRGFKLD----VETIRTLEEQRKSIQVEVENLQSTRNSISK 56
Query: 60 EIGKRRKKGEPVEELLAKSK--EIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIG 117
+IG+ G+ K + + +++ + E++ + ++D +PNI +VP G
Sbjct: 57 QIGQLMASGDKAGAEAVKQQIGTLGDDLDAKKVELDAVMAQLDAITQTVPNIPDDAVPNG 116
Query: 118 ESEEDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARA 177
+ + +NV + WG + ++ +EV K HVDL E+ G DFA A
Sbjct: 117 KDDSENVEVSRWGTPKTYD---------------FEV-----KDHVDLGEMGDGLDFASA 156
Query: 178 AKVSGSRFYYLLNEIVILDLALIRFALD-ELIKKGFTPVIPPYMVRRFVEEGSTTFEDF- 235
K++G+RF + + L A+ +F LD + G+T + PY+V G+ F
Sbjct: 157 TKITGARFVVMKGQFARLHRAIAQFMLDLHTDQHGYTELYVPYLVNAETLFGTGQLPKFG 216
Query: 236 ------EDVIYKVEGED---LYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEA 286
E + K E+ L LIPTAE P+ + + ILD +LPL +PCFR EA
Sbjct: 217 QDLFHTEPLTEKASDEEPRRLSLIPTAEVPVTNLVRDTILDEAELPLKMTAHTPCFRSEA 276
Query: 287 GTAGKDTKGIFRVHQFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTG 346
G+ G+DT+G+ R+HQF KVE +RPE+S E + +AE++ Q LE+PYR V +CTG
Sbjct: 277 GSYGRDTRGLIRMHQFDKVELVQITRPEDSMAALEELTGHAEKVLQLLELPYRKVILCTG 336
Query: 347 DLGYVAAKKYDIEAWMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNST 406
D+G+ + K YD+E W+P Q +RE+ S SN D+QARR+ RFR + ++KP VHTLN +
Sbjct: 337 DMGFGSCKTYDLEVWVPAQKTYREISSCSNMWDFQARRMQARFRRKGEKKPELVHTLNGS 396
Query: 407 AIATSRAIVAILENHQEEDGTVKIPKVLWKYTG 439
+A R +VAILEN+QE DG + IP VL KY G
Sbjct: 397 GLAVGRTMVAILENYQEADGRIAIPAVLQKYMG 429
>pir||C81742 seryl-tRNA synthetase TC0102 [imported] - Chlamydia muridarum
(strain Nigg) >gi|7190137|gb|AAF38982.1| (AE002277)
seryl-tRNA synthetase [Chlamydia muridarum]
Length = 428
Score = 266 bits (673), Expect = 4e-70
Identities = 161/446 (36%), Positives = 240/446 (53%), Gaps = 26/446 (5%)
Query: 1 MLDIKLIRENPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIE 60
MLDI+LIR+ P+ + L+K+ + + +L LD R + L R ++ +
Sbjct: 1 MLDIRLIRKEPKECEARLQKKDPSISL---ERLLDLDKNVRQLKADSESLLARRKALSGQ 57
Query: 61 IGKRRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGESE 120
I K + E L+ I ++ + EK ++E + + + RLPN VP+ +
Sbjct: 58 IHKAKVANEDATPLIQGVNAIADQLVAFEKTLQEQEALLLDLMARLPNYPDEDVPVSPDK 117
Query: 121 EDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARAAKV 180
N I+ G E + PK HV L E L DF AK
Sbjct: 118 SGNKIIKSHG--------------------EIPTFTFPPKHHVQLNEKLQILDFKLPAKT 157
Query: 181 SGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEGSTTFEDFEDVIY 240
SGS + NE V+L+ AL+ + L++ GF +PP +V+R + GS F+ Y
Sbjct: 158 SGSGWPAYKNEGVLLEWALLTYLLNKQQAHGFQLWLPPLLVKRDILFGSGQIPKFDGQYY 217
Query: 241 KVEG--EDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKGIFR 298
+VE + L+LIPTAE L G H+ EIL+ +DLPL Y +PCFR+EAG G +G+ R
Sbjct: 218 RVEDGEQSLFLIPTAEVVLNGFHSQEILNEQDLPLYYAAFTPCFRREAGAGGSHERGLVR 277
Query: 299 VHQFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKYDI 358
VHQFHKVE F ++ PE+ ++++I EE+ +L++PY++ + TGD+ + A K D
Sbjct: 278 VHQFHKVEMFAFTTPEQEEIAYQKMIGIVEEILSELQLPYQLSLLSTGDMSFTAKKTIDA 337
Query: 359 EAWMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIVAIL 418
E W+PGQ F EV S S C D+Q+RR R+RD K +V+TLN + +AT R +VAIL
Sbjct: 338 EVWLPGQQAFYEVSSISKCGDFQSRRSETRYRD-AQGKLHFVNTLNGSGLATPRLLVAIL 396
Query: 419 ENHQEEDGTVKIPKVLWKYTGFKEIV 444
EN+Q+EDG+V IP L Y +EI+
Sbjct: 397 ENYQQEDGSVVIPHALRPYMNNQEIL 422
>sp|Q9ZCG5|SYS_RICPR SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) (SERRS)
>gi|7437684|pir||A71639 serine--tRNA ligase (EC
6.1.1.11) (serS) RP783 - Rickettsia prowazekii
>gi|3861310|emb|CAA15209.1| (AJ235273) SERYL-TRNA
SYNTHETASE (serS) [Rickettsia prowazekii]
Length = 425
Score = 262 bits (663), Expect = 5e-69
Identities = 163/441 (36%), Positives = 241/441 (53%), Gaps = 28/441 (6%)
Query: 1 MLDIKLIRENPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIE 60
ML+IK IREN EL L +R +E + +I LD E R I + +H R +
Sbjct: 1 MLNIKWIRENQELFDEKLSQRF-IEPMS--SKIAMLDQEKRKITSLIQEFQHARKVKSKI 57
Query: 61 IGKR-RKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGES 119
+G K GE EEL I +++ LE+ ++ +++ L LPNI VP G
Sbjct: 58 LGNMVSKSGEEFEELQRDVNHINEKLAELEQNLDN-NNELNELLNMLPNIPDEEVPYGID 116
Query: 120 EEDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARAAK 179
N +R +GK + + K +E+ KL++ DF + AK
Sbjct: 117 GSMNKLVRAYGKTN----------KNALNKQHFEL---GTKLNL--------MDFEQTAK 155
Query: 180 VSGSRFYYLLNEIVILDLALIRFALDELIKK-GFTPVIPPYMVRRFVEEGSTTFEDFEDV 238
+SGSRF L ++ L+ ALI F +D K+ F + PP++VR + F +
Sbjct: 156 ISGSRFVTLKGDLAKLERALINFMIDIHTKEFDFFEISPPFLVRDRAMYNAGQLPKFSEE 215
Query: 239 IYKVEGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKGIFR 298
+ + LIPTAE L + A+ I+ + LP+ YV + CFR EAG++G+DT+G+ R
Sbjct: 216 SF-ITTNGYRLIPTAEVSLVNIVADTIIQREKLPMRYVAYTTCFRSEAGSSGRDTRGMIR 274
Query: 299 VHQFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKYDI 358
+HQF KVE + PEES HE I +E + +KL++PYRV+ +CTGD+G+ A K YDI
Sbjct: 275 LHQFGKVELVSITTPEESKNEHEYITNASETILKKLDLPYRVMLLCTGDMGFAAKKTYDI 334
Query: 359 EAWMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIVAIL 418
E W+PGQ ++RE+ S SNC D+QARR+ R+++ + VHTLN++ + R IVAIL
Sbjct: 335 EVWLPGQNQYREIASCSNCGDFQARRMKARYKEFGSNETTLVHTLNASGLPIGRTIVAIL 394
Query: 419 ENHQEEDGTVKIPKVLWKYTG 439
EN+Q DG++ IP VL Y G
Sbjct: 395 ENYQNNDGSITIPDVLINYMG 415
>sp|P81434|SYS_BUCAP SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) (SERRS)
>gi|2947036|gb|AAC05434.1| (L43549) seryl-tRNA synthase
[Buchnera aphidicola]
Length = 427
Score = 260 bits (657), Expect = 3e-68
Identities = 154/441 (34%), Positives = 242/441 (53%), Gaps = 29/441 (6%)
Query: 1 MLDIKLIRENPELV-KNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAI 59
ML+ L+R + + K LKK+ +L+ I I L+ + + + L+++ N ++
Sbjct: 1 MLNPYLLRNQIDAISKKLLKKKFKLD----ISLISSLEKKRKKLQIKTENLQYKHNTLSA 56
Query: 60 EIGKRRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGES 119
K +K E E L + K + L+ E+ L++KI + +PNI VP G S
Sbjct: 57 LFKKEKKIQELDENLKRTLTKSSKNLSELKIELNLLQEKIHNFSLSIPNIPSDDVPEGNS 116
Query: 120 EEDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARAAK 179
E+N +++WGK R EY + + HV++ L D+ +AK
Sbjct: 117 SENNKIVKYWGKKR-----------------EYS---FAVRDHVEIGNKLNQLDWKSSAK 156
Query: 180 VSGSRFYYLLNEIVILDLALIRFALD-ELIKKGFTPVIPPYMVRRFVEEGSTTFEDFEDV 238
+SG+RF + I +L AL +F LD IK G+T PY+V G+ F D
Sbjct: 157 ISGARFIVMKGNIALLHRALSQFMLDLHTIKHGYTETYVPYLVNHDSLYGTGQLPKFTDD 216
Query: 239 IYKVEGED---LYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKG 295
++ + D LIPTAE PL + +N+IL+ +LP++ +PCFR EA + G+D+KG
Sbjct: 217 LFHINSIDKKKYVLIPTAEVPLTNLFSNQILNETELPIMLTAHTPCFRSEASSYGRDSKG 276
Query: 296 IFRVHQFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKK 355
+ R+HQF KVE +PE S E + +AE++ Q LE+PYR V +C G++G+ A K
Sbjct: 277 LIRLHQFDKVELVQIIQPELSMNALELLTHHAEKVLQLLELPYRKVLLCGGEMGFSATKT 336
Query: 356 YDIEAWMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIV 415
YD+E W P Q ++RE+ S SN +D+QARR+ R++ + ++ +VHTLN + +A R +
Sbjct: 337 YDLEVWFPSQKKYREISSCSNMSDFQARRMKTRYKKKKEKSNSFVHTLNGSGLAIGRTLA 396
Query: 416 AILENHQEEDGTVKIPKVLWK 436
AILEN+Q+ DG V IPK+L K
Sbjct: 397 AILENYQDSDGRVTIPKILQK 417
>sp|P43833|SYS_HAEIN SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) (SERRS)
>gi|1075300|pir||I64048 serine--tRNA ligase (EC
6.1.1.11) - Haemophilus influenzae (strain Rd KW20)
>gi|1573062|gb|AAC21787.1| (U32696) seryl-tRNA
synthetase (serS) [Haemophilus influenzae Rd]
Length = 429
Score = 259 bits (656), Expect = 4e-68
Identities = 153/448 (34%), Positives = 246/448 (54%), Gaps = 36/448 (8%)
Query: 10 NPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINK--------LRHERNKIAIEI 61
+P L++N+L + E K+K LD E L++ K L+ ERN + I
Sbjct: 3 DPNLLRNNLAEVAEKLKVK---RNFMLDTEKLTALEDQRKNLQVTTENLQAERNARSKAI 59
Query: 62 GKRRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGESEE 121
G + +GE + LLA+ ++ ++ + +++ + +I+ +PN+ VP+G+ +
Sbjct: 60 GAAKARGEDIAPLLAEMDDMGNQLTEAKAQLDAVLAEINQIALSIPNLPADEVPLGKDDT 119
Query: 122 DNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARAAKVS 181
+N I WG R ++ +EV K H+ L E G DFA AK++
Sbjct: 120 ENKEILRWGTPRTFD---------------FEV-----KDHITLGEEANGLDFAAGAKLA 159
Query: 182 GSRFYYLLNEIVILDLALIRFALD-ELIKKGFTPVIPPYMVRRFVEEGSTTFEDF-EDVI 239
G+RF + +I + AL +F LD + G+ PY+V G+ F ED+
Sbjct: 160 GARFAVMKGQIAKMHRALAQFMLDLHTEQHGYLETYVPYLVNHATLYGTGQLPKFGEDLF 219
Query: 240 YKV--EGEDLY-LIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKGI 296
+ + EGE Y LIPTAE P+ + + I+D +LP+ +PCFR EAG+ G+DT+G+
Sbjct: 220 HTLALEGEQPYALIPTAEVPVTNLVRDVIIDEAELPIKMTAHTPCFRSEAGSYGRDTRGL 279
Query: 297 FRVHQFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKY 356
R+HQF KVE P++S E E + +AE++ Q L +PYR V +CTGD+G+ + K Y
Sbjct: 280 IRMHQFDKVEMVQIVDPDKSMEALEELTGHAEKVLQLLNLPYRKVLLCTGDMGFGSCKTY 339
Query: 357 DIEAWMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIVA 416
D+E W+P Q +RE+ S SN D+QARR+ R + + D+K R VHTLN + +A R +VA
Sbjct: 340 DLEVWVPAQNTYREISSCSNMWDFQARRMQARCKAKGDKKTRLVHTLNGSGLAVGRTLVA 399
Query: 417 ILENHQEEDGTVKIPKVLWKYTGFKEIV 444
+LEN+Q DG++ +P+ L Y G +++
Sbjct: 400 VLENYQNADGSITVPEELRPYMGGLDVI 427
>sp|P57398|SYS_BUCAI SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) (SERRS)
>gi|10038986|dbj|BAB13021.1| (AP001118) seryl-tRNA
synthetase [Buchnera sp. APS]
Length = 427
Score = 258 bits (653), Expect = 8e-68
Identities = 147/445 (33%), Positives = 243/445 (54%), Gaps = 48/445 (10%)
Query: 10 NPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIEIGKRRKKGE 69
NP L++N+L + ++LK ++ + +I+ + +R + I+ + K
Sbjct: 3 NPYLLRNELHLTAK--------KLLKKG--YKLNISKISSMEEKRKTLQIQTENLQFKHN 52
Query: 70 PVEELLAKSKEIVKRIESLEKEV--------------EELKKKIDYYLWRLPNITHPSVP 115
+ L ++K I + E L +V LK+KI ++ +PNI VP
Sbjct: 53 ALSNLFKENKNIKNKNELLRHQVIQSSKDLNASKIELNSLKEKIHHFSMCIPNIPSDDVP 112
Query: 116 IGESEEDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFA 175
G + +N I++WG+ + K ++E+ + H++L + D+
Sbjct: 113 EGNTSINNKEIKYWGQKK---------------KYDFEIQD-----HIELGKKFNELDWK 152
Query: 176 RAAKVSGSRFYYLLNEIVILDLALIRFALD-ELIKKGFTPVIPPYMVRRFVEEGSTTFED 234
+A++SGSRF + +I +L AL +F LD +K G+ PY+V G+
Sbjct: 153 SSAQMSGSRFVIMKGKIALLHRALSQFMLDLHTLKHGYIESYVPYLVHSEALYGTGQLPK 212
Query: 235 FEDVIYKVEGED---LYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGK 291
F D ++ + D LIPT E PL + ++I+D KDLP++ +PCFR EA + G+
Sbjct: 213 FSDDLFHINLTDKKKYILIPTGEVPLTNLVYDQIIDEKDLPIMLTAHTPCFRSEASSYGR 272
Query: 292 DTKGIFRVHQFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYV 351
DTKG+ R+HQF KVE +PE+S+E E++ +AE++ Q L +PYR + +CTGD G+
Sbjct: 273 DTKGLIRLHQFDKVELVQIVKPEKSYEALEKLTNHAEKVLQLLNLPYRKMLLCTGDTGFA 332
Query: 352 AAKKYDIEAWMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATS 411
A K YD+E W P + ++REV S SN +D+QARR+ R+R ++++K +VHTLN + +A
Sbjct: 333 AVKTYDLEVWFPSEKKYREVSSCSNMSDFQARRIKARYRKKSEQKNFFVHTLNGSGLAIG 392
Query: 412 RAIVAILENHQEEDGTVKIPKVLWK 436
R + AILEN+Q +G ++IPKVL K
Sbjct: 393 RTLAAILENYQHSNGRIEIPKVLQK 417
>pir||E82577 seryl-tRNA synthetase XF2286 [imported] - Xylella fastidiosa
(strain 9a5c) >gi|9107447|gb|AAF85085.1|AE004040_10
(AE004040) seryl-tRNA synthetase [Xylella fastidiosa]
Length = 432
Score = 257 bits (649), Expect = 2e-67
Identities = 146/396 (36%), Positives = 221/396 (54%), Gaps = 26/396 (6%)
Query: 45 KEINKLRHERNKIAIEIGKRRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLW 104
+E+ LR+ ++K IG+ R KGE V L+A+ +++ E +EE++ +++
Sbjct: 52 QELQSLRNSKSKA---IGQARSKGEDVSSLMAEVAAFSDDLKASEIALEEIRTELEKVAL 108
Query: 105 RLPNITHPSVPIGESEEDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVD 164
+PN+ VP+G E DNV WG R ++ + K HV+
Sbjct: 109 GIPNLPQQDVPLGADERDNVEQARWGVPRTFDFSI--------------------KDHVE 148
Query: 165 LLEILGGADFARAAKVSGSRFYYLLNEIVILDLALIRFALDELIKK-GFTPVIPPYMVRR 223
L G D AAK+SG+RF L I L AL + LD +++ G+ V P +V
Sbjct: 149 LGACHGWLDAESAAKLSGARFTVLRGPIARLHRALAQCMLDLHVRQHGYEEVNVPIIVNA 208
Query: 224 FVEEGSTTFEDFEDVIYKVE-GED-LYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPC 281
G+ FE+ ++ + GE YLI T+E L + NEI++ LPL S C
Sbjct: 209 DSLYGTGQLPKFEEDMFSTQLGEHRRYLISTSEISLTNLVRNEIIEADRLPLRMAAHSLC 268
Query: 282 FRKEAGTAGKDTKGIFRVHQFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVV 341
FR EAG+ G+DT+G+ R HQF KVE +P+ES H+R+ R AE + + L +PYR +
Sbjct: 269 FRSEAGSGGRDTRGMIRQHQFEKVELVSVCKPQESEGEHQRMTRCAETVLEMLGLPYRKI 328
Query: 342 NICTGDLGYVAAKKYDIEAWMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVH 401
+CTGD+G+ A K YD+E W+P QG +RE+ S SNC D+QARR+ R+R+ KP VH
Sbjct: 329 LLCTGDMGFAATKTYDLEVWLPSQGMYREISSCSNCGDFQARRMQARWRNSVTGKPELVH 388
Query: 402 TLNSTAIATSRAIVAILENHQEEDGTVKIPKVLWKY 437
TLN + +A RA++A++EN+Q DG++ +P+VL Y
Sbjct: 389 TLNGSGVAVGRAMIAVMENYQNADGSITVPEVLRPY 424
>sp|P47251|SYS_MYCGE SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) (SERRS)
>gi|1361847|pir||E64200 serine--tRNA ligase (EC
6.1.1.11) - Mycoplasma genitalium
>gi|1045673|gb|AAC71221.1| (U39679) seryl-tRNA
synthetase (serS) [Mycoplasma genitalium]
Length = 417
Score = 256 bits (648), Expect = 3e-67
Identities = 149/443 (33%), Positives = 240/443 (53%), Gaps = 27/443 (6%)
Query: 1 MLDIKLIRENPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIE 60
MLD +R N + K L +R E++ +++ ++ D R L+++ +++ +A +
Sbjct: 1 MLDPNKLRNNYDFFKKKLLERNVNEQL--LNQFIQTDKLMRKNLQQLELANQKQSLLAKQ 58
Query: 61 IGKRRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGESE 120
+ K++ ++LLA+SKE+ ++IE+L ++ + L PNI H SVP+G++E
Sbjct: 59 VAKQKDN----KKLLAESKELKQKIENLNNAYKDSQNISQDLLLNFPNIAHESVPVGKNE 114
Query: 121 EDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARAAKV 180
N+ + G+ V++ ++P H +L E L F +A K+
Sbjct: 115 SANLELLKEGRKPVFD--------------------FKPLPHRELCEKLNLVAFDKATKI 154
Query: 181 SGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEGSTTFEDFEDVIY 240
SG+RF ++ L A+ +D L K + P ++ + F+D ++
Sbjct: 155 SGTRFVAYTDKAAKLLRAITNLMID-LNKSKYQEWNLPVVINELSLRSTGQLPKFKDDVF 213
Query: 241 KVEGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKGIFRVH 300
K+E YL PT E L +HANEI + +DLP Y FR+EAG+AGK TKG R+H
Sbjct: 214 KLENTRYYLSPTLEVQLINLHANEIFNEEDLPKYYTATGINFRQEAGSAGKQTKGTIRLH 273
Query: 301 QFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKYDIEA 360
QF K E + +PE + E ++R+AE++ + L++P+R + +CTGD+G+ A K YD+E
Sbjct: 274 QFQKTELVKFCKPENAINELEAMVRDAEQILKALKLPFRRLLLCTGDMGFSAEKTYDLEV 333
Query: 361 WMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIVAILEN 420
WM +REV S S+C D+QARR IR++D + K YV TLN TA++ R AILEN
Sbjct: 334 WMAASNEYREVSSCSSCGDFQARRAMIRYKDINNGKNSYVATLNGTALSIDRIFAAILEN 393
Query: 421 HQEEDGTVKIPKVLWKYTGFKEI 443
Q +DG + IP+ L KY F I
Sbjct: 394 FQTKDGKILIPQALKKYLDFDTI 416
>sp|P75107|SYS_MYCPN SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) (SERRS)
>gi|2146648|pir||S73475 serine--tRNA ligase (EC
6.1.1.11) serS - Mycoplasma pneumoniae (strain ATCC
29342) >gi|1673809|gb|AAB95797.1| (AE000016) seryl-tRNA
synthetase [Mycoplasma pneumoniae]
Length = 420
Score = 251 bits (635), Expect = 1e-65
Identities = 161/446 (36%), Positives = 238/446 (53%), Gaps = 33/446 (7%)
Query: 1 MLDIKLIRENPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIE 60
MLD +R N + K L +RG E + ++ D R L +I ++ +A +
Sbjct: 1 MLDRNKLRNNLDFFKKKLVERGVSES--QFEAYVQADKAMRKLLHQIELANQKQTLLAQQ 58
Query: 61 IGKRRKKGEPVEELLAKSKEIVKRIESLE---KEVEELKKKIDYYLWRLPNITHPSVPIG 117
+ K KKG+P +LL +SKE+ +++E L KE E L +++ L LPNI SVP+G
Sbjct: 59 VAK--KKGDP--KLLKESKELKQKLEQLNIAFKEAETLSQEL---LLNLPNIADESVPVG 111
Query: 118 ESEEDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARA 177
E N+ + G+ V++ + P H +L E L F +A
Sbjct: 112 RDETANLELLKEGRKPVFD--------------------FTPLPHWELCERLQLVAFDKA 151
Query: 178 AKVSGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEGSTTFEDFED 237
K++G+RF ++ L A+ +D L K + P +V G+ F+D
Sbjct: 152 TKLTGARFVAYTDKAAKLLRAIASLMID-LNKNKYQEWNVPVIVNETSLTGTGQLPKFKD 210
Query: 238 VIYKVEGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKGIF 297
++K+E YL PT E LA +HANEI +LP Y FR+EAG+AGK TKG
Sbjct: 211 DVFKLENTRYYLSPTLEVQLANLHANEIFTEGELPKYYTATGVNFRQEAGSAGKQTKGTI 270
Query: 298 RVHQFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKYD 357
R+HQF KVE + +P E+ E + R+AE++ +L+IP+R + +C+GD+G+ A K YD
Sbjct: 271 RLHQFQKVELVKFCKPSEAIHELEEMTRDAEQILLELKIPFRRLLLCSGDMGFSAQKTYD 330
Query: 358 IEAWMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIVAI 417
+E WM G +REV S S+C D+QARR IR++D T K YV TLN TA+A R AI
Sbjct: 331 LEVWMAGCNEYREVSSCSSCGDFQARRAMIRYKDLTTGKNTYVATLNGTALAIDRIFAAI 390
Query: 418 LENHQEEDGTVKIPKVLWKYTGFKEI 443
LE++Q + G V IP+ L KY F +I
Sbjct: 391 LEHYQTKAGEVMIPQALLKYLDFDKI 416
>gi|6321799 Seryl-tRNA synthetase; Dia4p [Saccharomyces cerevisiae]
>gi|731635|sp|P38705|YHH1_YEAST PUTATIVE SERYL-TRNA
SYNTHETASE YHR011W (SERINE--TRNA LIGASE) (SERRS)
>gi|626922|pir||S46786 serine--tRNA ligase homolog -
yeast (Saccharomyces cerevisiae)
>gi|500705|gb|AAB68940.1| (U10400) Yhr011wp
[Saccharomyces cerevisiae]
Length = 446
Score = 239 bits (604), Expect = 4e-62
Identities = 158/445 (35%), Positives = 244/445 (54%), Gaps = 37/445 (8%)
Query: 3 DIKLIRENPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINK----LRHERNKIA 58
D+K I E + ++ R EL + I L+L E +KEI+K ++ +R I
Sbjct: 22 DVKKIIEMIPQYQTSIQNR-ELIEADSIIRSLQLLGERYQNIKEIDKVIADIQIQRKSIE 80
Query: 59 IEIGKRRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGE 118
+I K + K + E A K + ++ + ELKKKI LPN P+VP+
Sbjct: 81 AQIKKDKTK---ITEYSAALKALKEQYNDQNSKSSELKKKILETCKSLPNTLDPTVPLDA 137
Query: 119 SEEDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARAA 178
+ +E+++ + E + HVD++ D A+
Sbjct: 138 PQ------------------IEQWINPLKTHKTSEA-----QAHVDIMLKKNMLDLQTAS 174
Query: 179 KVSGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRR-FVEEGSTTFEDF-- 235
V+G +YYLLN+ L+ AL+ +AL + + GF+ +PP + ++ ++ D
Sbjct: 175 NVTGMSWYYLLNDGARLEQALVAYALKKANENGFSSCVPPSITKKELIDACGFNPRDMNN 234
Query: 236 EDVIYKVEGEDLYLIPTAEHPLAGMHANEILD--GKDLPLLYVGISPCFRKEAGTAGKDT 293
E IY ++ +L L+ TAE PLAG+ AN++L+ + VG+S C+R EAG GKDT
Sbjct: 235 ERQIYALQDTNLGLVATAEIPLAGLGANKVLELNSGECSKKLVGVSRCYRAEAGARGKDT 294
Query: 294 KGIFRVHQFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAA 353
KG++RVH+F KVE F +S+PE S + E I + + ++L IP +V+N+ + DLG A
Sbjct: 295 KGLYRVHEFTKVELFCWSKPETSAKVLEEIKQFQISVVEELGIPAKVLNMPSNDLGNPAF 354
Query: 354 KKYDIEAWMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRA 413
KKYDIEAWMPG+G+F E+ SASNCTD+Q+RRLN ++RD K YVHTLN TA+A R
Sbjct: 355 KKYDIEAWMPGRGKFGEISSASNCTDFQSRRLNTKYRDDNTGKLEYVHTLNGTAMAIPRV 414
Query: 414 IVAILEN-HQEEDGTVKIPKVLWKY 437
IVA++EN + G + +P+ L ++
Sbjct: 415 IVALVENFYDPSTGKISVPECLREF 439
>pir||T50193 probable seryl-trna synthetase [imported] - fission yeast
(Schizosaccharomyces pombe) >gi|6469293|emb|CAB61772.1|
(AL133225) seryl-trna synthetase [Schizosaccharomyces
pombe]
Length = 454
Score = 225 bits (568), Expect = 7e-58
Identities = 150/448 (33%), Positives = 235/448 (51%), Gaps = 38/448 (8%)
Query: 1 MLDIKLIRENPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIE 60
+L+ K I +N E V+ + R + + +I L E + E L + +I ++
Sbjct: 24 ILNYKYIYQNAEAVQRNCINRNLQAIAETVPKIRSLIDEKESLKNEFFPLLSLKKEITLQ 83
Query: 61 IGKRRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGESE 120
I + E +L+ ++K + K+ E K + ++ + Y +PN T P+VP+G E
Sbjct: 84 IERCSDPNER-GKLVNEAKGLKKKTEEYNKIISKVTNDLYQYCLAVPNTTLPTVPVGP-E 141
Query: 121 EDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILG-GADFARAAK 179
+ V ++ G V + G ++ D L+I G + AA+
Sbjct: 142 DKAVVVQKIGSPLV----------KKTGSLK------------DHLQIANEGINLEDAAQ 179
Query: 180 VSGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFV----------EEGS 229
SG F Y +I +L++A+ +A+D I KG+ PVIPP +VR + EEG
Sbjct: 180 ASGHSFCYTTGDIALLEMAITNYAMDFAISKGWCPVIPPTIVRTDIALACGFQPRDEEGQ 239
Query: 230 TTFEDFEDVIYKVEGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTA 289
+E V LI TAE LA + + + + VG+S +R+EAG
Sbjct: 240 QIYELDSYTSPLVSSPKQCLIGTAEISLAALGFKKTFNNFTERKV-VGVSRAYRREAGAR 298
Query: 290 GKDTKGIFRVHQFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLG 349
GK+ +G++R+H+F KVE F ++ P S E I+ +E + L+IP R++N+ T +LG
Sbjct: 299 GKENRGLYRLHEFTKVELFAWTHPSRSSEMFNEIVNFQKEFVETLKIPARILNMPTAELG 358
Query: 350 YVAAKKYDIEAWMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIA 409
A++KYDIEAWMP + + E+ SASNC ++QARRL R+R+ D+ +VHTLN TA A
Sbjct: 359 SSASQKYDIEAWMPARQSYGEITSASNCLEYQARRLLTRYRN--DKDSGFVHTLNGTAAA 416
Query: 410 TSRAIVAILENHQEEDGTVKIPKVLWKY 437
R I+AILENHQ+EDGTVK+P+ L Y
Sbjct: 417 IPRLIIAILENHQQEDGTVKVPETLVPY 444
>dbj|BAA99558.1| (AB029949) mitochondrial seryl-tRNA synthetase [Mus musculus]
Length = 518
Score = 223 bits (563), Expect = 3e-57
Identities = 153/457 (33%), Positives = 240/457 (52%), Gaps = 39/457 (8%)
Query: 2 LDIKLIRENPELVKNDLK-KRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIE 60
LD++ + PE L+ ++GEL + I+ E R ++I L E+ +A
Sbjct: 58 LDMESVCACPEKAARSLELRKGELRPAD-LPAIISTWQELRQLREQIRSLEAEKEAVAEA 116
Query: 61 I--------GKRRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHP 112
+ + +K + L A+ +EI K++ L + +L++++ RLPN THP
Sbjct: 117 VRALLANQDSDQVQKDPQYQGLRARGREIRKQLTPLYPQETQLEEQLYQQALRLPNQTHP 176
Query: 113 SVPIGESEEDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGA 172
P+G+ + V +R G E ++P+ H+++ E L
Sbjct: 177 DTPVGDESQARV-VRVVG--------------------EKPAFSFQPRGHLEIGEKLDII 215
Query: 173 DFARAAKVSGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEG-STT 231
R + VSG R YYL +L L+ F L +L+ +GFTP+ P ++R V EG T
Sbjct: 216 RQKRLSHVSGHRSYYLRGAGAVLQHGLVNFTLSKLVSRGFTPMTVPDLLRGAVFEGCGMT 275
Query: 232 FEDFEDVIYKVEG---EDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGT 288
IY ++ EDL L TAE LAG + + +DLP+ V S C+R E T
Sbjct: 276 PNANPSQIYNIDPSRFEDLNLAGTAEVGLAGYFMDHSVAFRDLPVRMVCASTCYRAETDT 335
Query: 289 AGKDTKGIFRVHQFHKVEQFVYSRP--EESWEWHERIIRNAEELFQKLEIPYRVVNICTG 346
GK+ G++RVH F KVE F + P E+S + + + E+ +L + +RV+++ T
Sbjct: 336 -GKEPWGLYRVHHFTKVEMFGVTGPGLEQSSQLLDEFLSLQVEILTELGLHFRVLDMPTQ 394
Query: 347 DLGYVAAKKYDIEAWMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNST 406
+LG A +K+DIEAWMPG+GR+ EV SASNCTD+Q+RRL I F T E ++ HT+N+T
Sbjct: 395 ELGLPAYRKFDIEAWMPGRGRYGEVTSASNCTDFQSRRLYIMFETETGEL-QFAHTVNAT 453
Query: 407 AIATSRAIVAILENHQEEDGTVKIPKVLWKYTGFKEI 443
A A R ++A+LE++Q++DG+V +P L Y G I
Sbjct: 454 ACAVPRVLIALLESNQQKDGSVLVPAALQPYLGTDRI 490
>dbj|BAA99556.1| (AB029947) mitochondrial seryl-tRNA synthetase [Bos taurus]
Length = 518
Score = 221 bits (557), Expect = 1e-56
Identities = 153/458 (33%), Positives = 240/458 (51%), Gaps = 39/458 (8%)
Query: 1 MLDIKLIRENPELVKNDLK-KRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAI 59
+LD++ + PE L ++GEL K + I+ E R ++I L E+ +
Sbjct: 57 LLDMESLCAYPEDAARALDLRKGELRS-KDLPGIISTWQELRQLREQIRSLEEEKEAVTE 115
Query: 60 EI--------GKRRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITH 111
+ + ++ + L A+ +EI K++ L + +L+++ RLPN TH
Sbjct: 116 AVRALVVNQDNSQVQQDPQYQSLRARGREIRKQLTLLYPKEAQLEEQFYLRALRLPNQTH 175
Query: 112 PSVPIGESEEDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGG 171
P VP+G+ + V + G + ++P+ H+++ E L
Sbjct: 176 PDVPVGDESQARV-LHVVG--------------------DKPAFSFQPRGHLEIAEKLDI 214
Query: 172 ADFARAAKVSGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEG-ST 230
R + VSG R YYL +L L+ F L++LI +GFTP+ P ++R V EG
Sbjct: 215 IRQKRLSHVSGHRSYYLRGAGALLQHGLVNFTLNKLIHRGFTPMTVPDLLRGVVFEGCGM 274
Query: 231 TFEDFEDVIYKVEG---EDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAG 287
T IY ++ EDL L TAE LAG + + +DLP+ V S C+R E
Sbjct: 275 TPNAKPSQIYNIDPSRFEDLNLAGTAEVGLAGYFMDHSVAFRDLPIRMVCSSTCYRAETD 334
Query: 288 TAGKDTKGIFRVHQFHKVEQFVYSRP--EESWEWHERIIRNAEELFQKLEIPYRVVNICT 345
T GK+ G++RVH F KVE F + P E+S E E + E+ +L + +RV+++ T
Sbjct: 335 T-GKEPWGLYRVHHFTKVEMFGVTGPGLEQSSELLEEFLSLQMEILTELGLHFRVLDMPT 393
Query: 346 GDLGYVAAKKYDIEAWMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNS 405
+LG A +K+DIEAWMPG+GRF EV SASNCTD+Q+RRL+I F+ E ++ HT+N+
Sbjct: 394 QELGLPAYRKFDIEAWMPGRGRFGEVTSASNCTDFQSRRLHIMFQTEAGEL-QFAHTVNA 452
Query: 406 TAIATSRAIVAILENHQEEDGTVKIPKVLWKYTGFKEI 443
T A R ++A+LE++Q++DG+V +P L Y G I
Sbjct: 453 TGCAVPRLLIALLESYQQKDGSVLVPPALQPYLGTDRI 490
>gi|8923421 hypothetical protein FLJ20450 [Homo sapiens]
>gi|11432997|ref|XP_008900.1| hypothetical protein
FLJ20450 [Homo sapiens] >gi|7020557|dbj|BAA91176.1|
(AK000457) unnamed protein product [Homo sapiens]
>gi|9188535|dbj|BAA99557.1| (AB029948) mitochondrial
seryl-tRNA synthetase [Homo sapiens]
Length = 518
Score = 217 bits (547), Expect = 2e-55
Identities = 151/457 (33%), Positives = 239/457 (52%), Gaps = 39/457 (8%)
Query: 2 LDIKLIRENPELVKNDLK-KRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIE 60
LDI+ PE + L+ ++GEL + I+ E R ++I L E+ +
Sbjct: 58 LDIERFCACPEEAAHALELRKGELRSAD-LPAIISTWQELRQLQEQIRSLEEEKAAVTEA 116
Query: 61 IGK---RRKKGEPVEE-----LLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHP 112
+ + GE ++ L A+ +EI K + L +L+++ +LPN THP
Sbjct: 117 VRALLANQDSGEVQQDPKYQGLRARGREIRKELVHLYPREAQLEEQFYLQALKLPNQTHP 176
Query: 113 SVPIGESEEDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGA 172
VP+G+ + V K V ++P+ H+++ E L
Sbjct: 177 DVPVGDESQARVLHMVGDKP---------------------VFSFQPRGHLEIGEKLDII 215
Query: 173 DFARAAKVSGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEG-STT 231
R + VSG R YYL +L L+ F ++L+++GFTP+ P ++R V EG T
Sbjct: 216 RQKRLSHVSGHRSYYLRGAGALLQHGLVNFTFNKLLRRGFTPMTVPDLLRGAVFEGCGMT 275
Query: 232 FEDFEDVIYKVEG---EDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGT 288
IY ++ +DL L TAE LAG + + +DLP+ V S C+R E T
Sbjct: 276 PNANPSQIYNIDPARFKDLNLAGTAEVGLAGYFMDHTVAFRDLPVRMVCSSTCYRAETNT 335
Query: 289 AGKDTKGIFRVHQFHKVEQFVYSRP--EESWEWHERIIRNAEELFQKLEIPYRVVNICTG 346
G++ +G++RVH F KVE F + P E+S + E + E+ +L + +RV+++ T
Sbjct: 336 -GQEPRGLYRVHHFTKVEMFGVTGPGLEQSSQLLEEFLSLQMEILTELGLHFRVLDMPTQ 394
Query: 347 DLGYVAAKKYDIEAWMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNST 406
+LG A +K+DIEAWMPG+GRF EV SASNCTD+Q+RRL+I F+ E ++ HT+N+T
Sbjct: 395 ELGLPAYRKFDIEAWMPGRGRFGEVTSASNCTDFQSRRLHIMFQTEAGEL-QFAHTVNAT 453
Query: 407 AIATSRAIVAILENHQEEDGTVKIPKVLWKYTGFKEI 443
A A R ++A+LE++Q++DG+V +P L Y G I
Sbjct: 454 ACAVPRLLIALLESNQQKDGSVLVPPALQSYLGTDRI 490
>gb|AAF55175.1| (AE003708) Aats-ser gene product [Drosophila melanogaster]
Length = 417
Score = 184 bits (463), Expect = 2e-45
Identities = 130/421 (30%), Positives = 218/421 (50%), Gaps = 36/421 (8%)
Query: 40 WRAKLKEINKLRHERNKIAIEIGKRRKKGEPVEEL-----LAKSKEIVKRIESLEKEVE- 93
WR L + H+ + I + ++EL + K V I SL +E++
Sbjct: 10 WRPLLLLRRQRSHDAKAVEAPIHRPVPTSAQLDELERNVVVRHHKNNVPLIRSLIQELDA 69
Query: 94 ---ELKKKIDYYLWRLPNITHPSVPIGESEEDNVPIRFWGKARVWEGHLERFLEQSQGKM 150
+++ L +LPN THP + EE ++ + + L+ F E ++
Sbjct: 70 GDQHKLRQLQAELEQLPNATHPRLR-DYGEEPRELAQYVHRQLTPQSRLKEFSELARA-- 126
Query: 151 EYEVLEWRPKLHVDLLEILGGADFARAAKVSGSRFYYLLNEIVILDLALIRFALDELIKK 210
L++ ++ LG +G + YYL ++ L+ A+I++AL + +
Sbjct: 127 ----------LNLYRMDHLGN--------YTGHKSYYLTGQLATLEQAIIQYALQAVTEH 168
Query: 211 GFTPV-IPPYMVRRFVEEGSTTFEDFEDVIYKVEGEDLYLIPTAEHPLAGMHANEILDGK 269
GF + +P + + +E E +YK++ + L T+E LAG AN++L
Sbjct: 169 GFKLISVPDILPKEVIESCGMRTEGERTQVYKLDTGEC-LSGTSEMALAGFFANKLLSED 227
Query: 270 DLPLLYVGISPCFRKEAGTAG-KDTKGIFRVHQFHKVEQFVYSRPEESWEWHERIIRNAE 328
LPL +S C+R E T+G ++ KGI+RVHQF+KVE F E+S E
Sbjct: 228 QLPLKVTAVSRCYRAE--TSGLQEEKGIYRVHQFNKVEMFAICTEEQSEAELEEFKNIEV 285
Query: 329 ELFQKLEIPYRVVNICTGDLGYVAAKKYDIEAWMPGQGRFREVVSASNCTDWQARRLNIR 388
+LF++L + +R++++ +LG A +KYDIEAWMPG+ + E+ S SNCTD+QARRL IR
Sbjct: 286 DLFRRLGLNFRLLDMPPCELGAPAYQKYDIEAWMPGRQMWGEISSCSNCTDYQARRLGIR 345
Query: 389 FRDRTDEKPRYVHTLNSTAIATSRAIVAILENHQEEDGTVKIPKVLWKYTGFKEIVPVEK 448
+R D + + HT+N TA A R ++A+LE++Q+EDG ++IP VL + +E++ K
Sbjct: 346 YRRSADGQILHAHTINGTATAIPRLLIALLESYQKEDG-IEIPAVLRPFMDNQELITRNK 404
Query: 449 K 449
+
Sbjct: 405 R 405
>emb|CAA75101.1| (Y14823) seryl-tRNA synthetase [Drosophila melanogaster]
Length = 322
Score = 180 bits (453), Expect = 2e-44
Identities = 102/271 (37%), Positives = 164/271 (59%), Gaps = 6/271 (2%)
Query: 181 SGSRFYYLLNEIVILDLALIRFALDELIKKGFTPV-IPPYMVRRFVEEGSTTFEDFEDVI 239
+G + YYL ++ L+ A+I++AL + + GF + +P + + +E E +
Sbjct: 44 TGHKSYYLTGQLATLEQAIIQYALQAVTEHGFKLISVPDILPKEVIESCGMRTEGERTQV 103
Query: 240 YKVEGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAG-KDTKGIFR 298
YK++ + L T+E LAG AN++L LPL +S C+R E T+G ++ KGI+R
Sbjct: 104 YKLDTGEC-LSGTSEMALAGFFANKLLSEDQLPLKVTAVSRCYRAE--TSGLQEEKGIYR 160
Query: 299 VHQFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKYDI 358
VHQF+KVE F E+S E +LF++L + +R++++ +LG A +KYDI
Sbjct: 161 VHQFNKVEMFAICTEEQSEAELEEFKNIEVDLFRRLGLNFRLLDMPPCELGAPAYQKYDI 220
Query: 359 EAWMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIVAIL 418
EAWMPG+ + E+ S SNCTD+QARRL IR+R D + + HT+N TA A R ++A+L
Sbjct: 221 EAWMPGRQMWGEISSCSNCTDYQARRLGIRYRRSADGQILHAHTINGTATAIPRLLIALL 280
Query: 419 ENHQEEDGTVKIPKVLWKYTGFKEIVPVEKK 449
E++Q+EDG ++IP VL + +E++ K+
Sbjct: 281 ESYQKEDG-IEIPAVLRPFMDNQELITRNKR 310
>gb|AAA83842.1| (J03412) ORF X; putative [Escherichia coli]
Length = 180
Score = 180 bits (451), Expect = 4e-44
Identities = 81/179 (45%), Positives = 120/179 (66%)
Query: 266 LDGKDLPLLYVGISPCFRKEAGTAGKDTKGIFRVHQFHKVEQFVYSRPEESWEWHERIIR 325
+D DLP+ +PCFR EAG+ G+DT+G+ R+HQF KVE RPE+S E +
Sbjct: 1 IDEDDLPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTG 60
Query: 326 NAEELFQKLEIPYRVVNICTGDLGYVAAKKYDIEAWMPGQGRFREVVSASNCTDWQARRL 385
+AE++ Q L +PYR + +CTGD+G+ A K YD+E W+P Q +RE+ S SN D+QARR+
Sbjct: 61 HAEKVLQLLGLPYRKIILCTGDMGFGACKTYDLEVWIPAQNTYREISSCSNVWDFQARRM 120
Query: 386 NIRFRDRTDEKPRYVHTLNSTAIATSRAIVAILENHQEEDGTVKIPKVLWKYTGFKEIV 444
R R ++D+K R VHTLN + +A R +VA++EN+Q+ DG +++P+VL Y E +
Sbjct: 121 QARCRSKSDKKTRLVHTLNGSGLAVGRTLVAVMENYQQADGRIEVPEVLRPYMNGLEYI 179
>sp|P26636|SYS_CRIGR SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) (SERRS)
>gi|479795|pir||S35441 serine--tRNA ligase (EC 6.1.1.11)
- Chinese hamster (fragment) >gi|553843|gb|AAA37019.1|
(M88136) transfer RNA-Ser synthetase [Cricetulus
griseus]
Length = 199
Score = 173 bits (434), Expect = 4e-42
Identities = 87/165 (52%), Positives = 116/165 (69%), Gaps = 7/165 (4%)
Query: 290 GKDTKGIFRVHQFHKVEQFVYSRPEE--SWEWHERIIRNAEELFQKLEIPYRVVNICTGD 347
G+DT+GIFRVHQF K+EQFVY+ P + SWE E +I AEE +Q L IPY +VNI +G
Sbjct: 3 GRDTRGIFRVHQFEKIEQFVYTSPHDNKSWEMFEEMIGTAEEFYQSLGIPYHIVNIVSGS 62
Query: 348 LGYVAAKKYDIEAWMPGQGRFREVVSASNCTDWQARRLNIRF--RDRTDEKPRYVHTLNS 405
L + A+KK D+EAW PG G FRE+VS SNCTD+QARRL IR+ + +K +VH LN+
Sbjct: 63 LNHAASKKLDLEAWFPGSGAFRELVSCSNCTDYQARRLRIRYGQTKKMMDKVEFVHMLNA 122
Query: 406 TAIATSRAIVAILENHQEEDGTVKIPKVLWKY--TGFKEIVPVEK 448
T AT+R I AILEN+Q E G + +P+ L ++ G +E++P K
Sbjct: 123 TMCATTRTICAILENYQTEKGII-VPEKLREFMPPGLQELIPFVK 166
>pir||T34480 hypothetical protein W03B1.4 - Caenorhabditis elegans
>gi|3258589|gb|AAC24441.1| (U58753) W03B1.4 gene product
[Caenorhabditis elegans]
Length = 546
Score = 169 bits (425), Expect = 4e-41
Identities = 126/401 (31%), Positives = 198/401 (48%), Gaps = 41/401 (10%)
Query: 50 LRHERNKIAIEIGKRRKKGE-PVEELLAKSKEIVKRIESLEKEVEELKKKIDY-YLWR-- 105
L E+N AI +KG ++++ K I K ++S EK+ + Y LW
Sbjct: 155 LLDEKNLEAIRENILNRKGVGDIDKVHKKWAVIQKMMKSGEKQTNGAVSEQKYKQLWDEL 214
Query: 106 ------LPNITHPSVPIGESEEDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRP 159
+PN+T VP G ++ + + WG+ R E E V WR
Sbjct: 215 YDEAILIPNMTQDGVPRGSEDQAKI-VAEWGEKR----------EDECLTAEKLVQTWRS 263
Query: 160 KLHVDLLEILGGADFARAAKVSGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPY 219
LH SG R Y L + L+ AL+ +A + + GF P+ P
Sbjct: 264 LLH--------------PTDASGQRSYVFLGALASLEKALLDYAHERVCALGFRPITVPD 309
Query: 220 MVRRFVEEGSTTFEDFEDVI-YKVEGEDLY--LIPTAEHPLAGMHANEILDGKDLPLLYV 276
+V V + + + I Y + GE+ + L TAE +A + LP+ V
Sbjct: 310 IVSGEVTQACGVMQRSDHPIQYTLAGEESHTKLSGTAEMGIAAFLRGRTFNQDQLPIRLV 369
Query: 277 GISPCFRKEAGTAGKDTKGIFRVHQFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEI 336
+S CFR E + + K ++RVH+F KVE FV S PE+S + ++ + FQ L +
Sbjct: 370 SLSRCFRTEISKSASEAK-LYRVHEFSKVEMFVVSTPEQSAAELDYLVEVQKGTFQALGV 428
Query: 337 PYRVVNICTGDLGYVAAKKYDIEAWMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEK 396
R + + + +LG AA+K+DIEAWMPG+ + EV SASNCTD+Q+RRL I+++ D
Sbjct: 429 HCRQLEMPSEELGASAARKFDIEAWMPGRKLYGEVSSASNCTDFQSRRLGIKYK-TADGT 487
Query: 397 PRYVHTLNSTAIATSRAIVAILENHQ-EEDGTVKIPKVLWK 436
+Y HT N TA+A++RA++++LE Q ++ G ++P+ L K
Sbjct: 488 TKYAHTCNGTALASTRALISVLETFQNDKKGLGELPEPLRK 528
>pir||T37315 serine--tRNA ligase (EC 6.1.1.11) - Caenorhabditis elegans
>gi|4239885|dbj|BAA74732.1| (AB016796) Seryl-tRNA
synthetase [Caenorhabditis elegans]
Length = 441
Score = 169 bits (425), Expect = 4e-41
Identities = 126/401 (31%), Positives = 198/401 (48%), Gaps = 41/401 (10%)
Query: 50 LRHERNKIAIEIGKRRKKGE-PVEELLAKSKEIVKRIESLEKEVEELKKKIDY-YLWR-- 105
L E+N AI +KG ++++ K I K ++S EK+ + Y LW
Sbjct: 50 LLDEKNLEAIRENILNRKGVGDIDKVHKKWAVIQKMMKSGEKQTNGAVSEQKYKQLWDEL 109
Query: 106 ------LPNITHPSVPIGESEEDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRP 159
+PN+T VP G ++ + + WG+ R E E V WR
Sbjct: 110 YDEAILIPNMTQDGVPRGSEDQAKI-VAEWGEKR----------EDECLTAEKLVQTWRS 158
Query: 160 KLHVDLLEILGGADFARAAKVSGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPY 219
LH SG R Y L + L+ AL+ +A + + GF P+ P
Sbjct: 159 LLH--------------PTDASGQRSYVFLGALASLEKALLDYAHERVCALGFRPITVPD 204
Query: 220 MVRRFVEEGSTTFEDFEDVI-YKVEGEDLY--LIPTAEHPLAGMHANEILDGKDLPLLYV 276
+V V + + + I Y + GE+ + L TAE +A + LP+ V
Sbjct: 205 IVSGEVTQACGVMQRSDHPIQYTLAGEESHTKLSGTAEMGIAAFLRGRTFNQDQLPIRLV 264
Query: 277 GISPCFRKEAGTAGKDTKGIFRVHQFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEI 336
+S CFR E + + K ++RVH+F KVE FV S PE+S + ++ + FQ L +
Sbjct: 265 SLSRCFRTEISKSASEAK-LYRVHEFSKVEMFVVSTPEQSAAELDYLVEVQKGTFQALGV 323
Query: 337 PYRVVNICTGDLGYVAAKKYDIEAWMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEK 396
R + + + +LG AA+K+DIEAWMPG+ + EV SASNCTD+Q+RRL I+++ D
Sbjct: 324 HCRQLEMPSEELGASAARKFDIEAWMPGRKLYGEVSSASNCTDFQSRRLGIKYK-TADGT 382
Query: 397 PRYVHTLNSTAIATSRAIVAILENHQ-EEDGTVKIPKVLWK 436
+Y HT N TA+A++RA++++LE Q ++ G ++P+ L K
Sbjct: 383 TKYAHTCNGTALASTRALISVLETFQNDKKGLGELPEPLRK 423
>sp|P26638|SYS_MOUSE SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) (SERRS)
>gi|200970|gb|AAA40108.1| (M74012) Seryl-RS [Mus
musculus]
Length = 283
Score = 94.4 bits (231), Expect = 2e-18
Identities = 81/303 (26%), Positives = 139/303 (45%), Gaps = 66/303 (21%)
Query: 1 MLDIKLIREN----PELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNK 56
+LD+ L R + P L++ +KR + + +D+++K D+EWR + L +N
Sbjct: 2 VLDLDLFRVDKGGDPALIRETQEKRFKDPGL--VDQLVKADSEWRRCRFRADNLNKLKNL 59
Query: 57 IAIEIGKRRKKGEPV-------------EELLAKSKEIVK--RIESLEKEVEELKKKID- 100
+ IG++ KK E V ++L A + +K +I+ + ++E +K D
Sbjct: 60 CSKTIGEKMKKKEAVGDDESVPENVLNFDDLTADALRALKVSQIKKVRLLIDEAIQKCDG 119
Query: 101 ----------YYLWRLPNITHPSVPIGESEE-DNVPIRFWGKARVWEGHLERFLEQSQGK 149
L + N+ HPSVPI E+ DN R WG V +
Sbjct: 120 ERVKLEAERFENLREIGNLLHPSVPISNDEDADNKVERIWGDCTV--------------R 165
Query: 150 MEYEVLEWRPKLHVDLLEILGGADFARAAKVSGSRFYYLLNEIVILDLALIRFALDELIK 209
+Y HVDL+ ++ G + + A V+GS +V L+ ALI++AL L
Sbjct: 166 KKYS--------HVDLVVMVDGFEGEKGAVVAGSPGVLPEGALVFLEQALIQYALRTLGS 217
Query: 210 KGFTPVIPPYMVRRFVEEGSTTFEDFEDVIYKVEG-----------EDLYLIPTAEHPLA 258
+G+TP+ P+ +R+ V + F++ +YKV G ++ YLI T+E P+A
Sbjct: 218 RGYTPIYTPFFMRKEVMQEVAQLSQFDEELYKVIGKGSEKSDDNSYDEKYLIATSEQPIA 277
Query: 259 GMH 261
+H
Sbjct: 278 ALH 280
>pir||A41019 serine--tRNA ligase (EC 6.1.1.11) - mouse (fragment)
Length = 284
Score = 92.8 bits (227), Expect = 7e-18
Identities = 82/304 (26%), Positives = 142/304 (45%), Gaps = 67/304 (22%)
Query: 1 MLDIKLIREN----PELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNK 56
+LD+ L R + P L++ +KR + + +D+++K D+EWR + L +N
Sbjct: 2 VLDLDLFRVDKGGDPALIRETQEKRFKDPGL--VDQLVKADSEWRRCRFRADNLNKLKNL 59
Query: 57 IAIEIGKRRKKGEPV-------------EELLAKSKEIVK--RIESLEKEVEELKKKID- 100
+ IG++ KK E V ++L A + +K +I+ + ++E +K D
Sbjct: 60 CSKTIGEKMKKKEAVGDDESVPENVLNFDDLTADALRALKVSQIKKVRLLIDEAIQKCDG 119
Query: 101 ----------YYLWRLPNITHPSVPIGESEE-DNVPIRFWGKARVWEGHLERFLEQSQGK 149
L + N+ HPSVPI E+ DN R WG V +
Sbjct: 120 ERVKLEAERFENLREIGNLLHPSVPISNDEDADNKVERIWGDCTV--------------R 165
Query: 150 MEYEVLEWRPKLHVDLLEILGGADFARAAKVSGSRFYYLLNEIVILDLALIRFALDELIK 209
+Y HVDL+ ++ G + + A V+GS +V L+ ALI++AL L
Sbjct: 166 KKYS--------HVDLVVMVDGFEGEKGAVVAGSPGVLPEGALVFLEQALIQYALRTLGS 217
Query: 210 KGFTPVIPPYMVRRFV-EEGSTTFEDFEDVIYKVEG-----------EDLYLIPTAEHPL 257
+G+TP+ P+ +R+ V +E + + F++ +YKV G ++ YLI T+E P+
Sbjct: 218 RGYTPIYTPFFMRKEVMQEVAQLSQQFDEELYKVIGKGSEKSDDNSYDEKYLIATSEQPI 277
Query: 258 AGMH 261
A +H
Sbjct: 278 AALH 281
>sp|O33780|SYS_SULSO SERYL-TRNA SYNTHETASE (SERINE--TRNA LIGASE) (SERRS)
>gi|2253629|gb|AAB63028.1| (U82227) seryl-tRNA
synthetase [Sulfolobus solfataricus]
Length = 100
Score = 72.6 bits (175), Expect = 9e-12
Identities = 36/97 (37%), Positives = 66/97 (67%), Gaps = 4/97 (4%)
Query: 4 IKLIRENPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIEIGK 63
++L+R+NPE +KN+LK+R + +D+ ++LD +WR L+E+ KLRH+ N ++ +I K
Sbjct: 6 LELLRKNPEDLKNNLKRRAI--DVSLVDKAVELDKKWRQVLQEVEKLRHQHNVLSSQISK 63
Query: 64 RRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKID 100
GE ++ + +SK ++K +E EKE+EE++ + D
Sbjct: 64 --LSGEERKKKIEESKNLLKILEEKEKELEEIENERD 98
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.319 0.139 0.416
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 181204780
Number of Sequences: 2977
Number of extensions: 8071267
Number of successful extensions: 32314
Number of sequences better than 1.0e-10: 72
Number of HSP's better than 0.0 without gapping: 69
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 31980
Number of HSP's gapped (non-prelim): 78
length of query: 455
length of database: 189,106,746
effective HSP length: 55
effective length of query: 400
effective length of database: 156,189,961
effective search space: 62475984400
effective search space used: 62475984400
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 167 (69.5 bits)