BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0889 (ilvC) DE:ketol-acid reductoisomerase (ilvC)
(332 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||H75044 ketol-acid reductoisomerase (ilvc) PAB0889 - Pyrococ... 666 0.0
sp|Q58938|ILVC_METJA KETOL-ACID REDUCTOISOMERASE (ACETOHYDROXY-A... 406 e-112
pir||D72362 ketol-acid reductoisomerase - Thermotoga maritima (s... 382 e-105
sp|O27491|ILVC_METTH KETOL-ACID REDUCTOISOMERASE (ACETOHYDROXY-A... 379 e-104
sp|O67289|ILVC_AQUAE KETOL-ACID REDUCTOISOMERASE (ACETOHYDROXY-A... 376 e-103
gi|11499567 ketol-acid reductoisomerase (ilvC) [Archaeoglobus fu... 369 e-101
gb|AAK40890.1| Ketol-acid reductoisomerase (ilvC-1) [Sulfolobus ... 358 5e-98
emb|CAB57724.1| (Y18930) ketol-acid reductoisomerase [Sulfolobus... 358 5e-98
dbj|BAB06778.1| (AP001517) ketol-acid reductoisomerase [Bacillus... 350 1e-95
sp|P37253|ILVC_BACSU KETOL-ACID REDUCTOISOMERASE (ACETOHYDROXY-A... 345 5e-94
pir||C75387 ketol-acid reductoisomerase - Deinococcus radioduran... 344 1e-93
pir||F81066 ketol-acid reductoisomerase NMB1574 [imported] - Nei... 338 5e-92
pir||C81801 ketol-acid reductoisomerase (EC 1.1.1.86) NMA1763 [i... 338 5e-92
gb|AAD32178.1|AF125563_3 (AF125563) ketol-acid reductoisomerase ... 337 8e-92
gb|AAG39032.1|AF220670_3 (AF220670) alpha-keto-beta-hydroxylacil... 330 2e-89
sp|Q02138|ILVC_LACLA KETOL-ACID REDUCTOISOMERASE (ACETOHYDROXY-A... 329 2e-89
pir||A47037 ketol-acid reductoisomerase (EC 1.1.1.86) - Synechoc... 329 2e-89
sp|P29107|ILVC_SYNY3 KETOL-ACID REDUCTOISOMERASE (ACETOHYDROXY-A... 329 2e-89
pir||G81411 ketol-acid reductoisomerase (EC 1.1.1.86) Cj0632 [im... 318 5e-86
pir||E83059 ketol-acid reductoisomerase PA4694 [imported] - Pseu... 315 4e-85
sp|Q59500|ILVC_MYCAV KETOL-ACID REDUCTOISOMERASE (ACETOHYDROXY-A... 315 5e-85
sp|O53248|ILVC_MYCTU KETOL-ACID REDUCTOISOMERASE (ACETOHYDROXY-A... 313 2e-84
gb|AAD29665.1|AF124757_25 (AF124757) acetohydroxy acid isomerore... 312 5e-84
sp|O33114|ILVC_MYCLE KETOL-ACID REDUCTOISOMERASE (ACETOHYDROXY-A... 309 2e-83
emb|CAC01643.1| (AL391072) ketol-acid reductoisomerase [Streptom... 309 4e-83
sp|Q9Z565|ILVC_STRCO KETOL-ACID REDUCTOISOMERASE (ACETOHYDROXY-A... 307 9e-83
gb|AAG10503.1|AF279106_65 (AF279106) predicted ketol-acid reduct... 307 1e-82
pir||E82634 ketol-acid reductoisomerase XF1822 [imported] - Xyle... 302 3e-81
sp|Q59818|ILVC_STRAW KETOL-ACID REDUCTOISOMERASE (ACETOHYDROXY-A... 299 3e-80
sp|O32414|ILVC_RHOMO KETOL-ACID REDUCTOISOMERASE (ACETOHYDROXY-A... 298 5e-80
sp|Q57179|ILVC_CORGL KETOL-ACID REDUCTOISOMERASE (ACETOHYDROXY-A... 297 1e-79
sp|P97115|ILVC_LEUMC KETOL-ACID REDUCTOISOMERASE (ACETOHYDROXY-A... 293 2e-78
pir||A71945 ketol-acid reductoisomerase - Helicobacter pylori (s... 275 4e-73
sp|O25097|ILVC_HELPY KETOL-ACID REDUCTOISOMERASE (ACETOHYDROXY-A... 275 5e-73
sp|Q52955|ILVC_RHIME KETOL-ACID REDUCTOISOMERASE (ACETOHYDROXY-A... 240 2e-62
pir||T40532 ketol-acid reductoisomerase precursor - fission yeas... 199 4e-50
sp|P78827|ILV5_SCHPO PROBABLE KETOL-ACID REDUCTOISOMERASE, MITOC... 191 1e-47
gi|6323387 acetohydroxyacid reductoisomerase; Ilv5p [Saccharomyc... 190 2e-47
gb|AAB33579.1| (S77496) acetohydroxy-acid isomeroreductase, Ilv5... 189 5e-47
gb|AAB33578.1| (S77495) acetohydroxy-acid isomeroreductase, Ilv5... 187 2e-46
sp|P38674|ILV5_NEUCR KETOL-ACID REDUCTOISOMERASE PRECURSOR (ACET... 187 2e-46
gb|AAK42136.1| Ketol-acid reductoisomerase (ilvC-3) [Sulfolobus ... 185 6e-46
gb|AAK41560.1| Ketol-acid reductoisomerase (ilvC-2) [Sulfolobus ... 183 3e-45
emb|CAA76356.1| (Y16743) ketol-acid reductoisomerase [Piromyces ... 167 1e-40
gb|AAF13803.1|AF130813_3 (AF130813) acetohydroxy acid isomerored... 164 2e-39
sp|P05793|ILVC_ECOLI KETOL-ACID REDUCTOISOMERASE (ACETOHYDROXY-A... 163 3e-39
gb|AAA24029.1| (M11689) acetohydroxy acid isomeroreductase [Esch... 162 4e-39
gb|AAF33476.1| (AF233324) S. typhimurium ketol-acid reductoisome... 161 1e-38
gb|AAF13807.1|AF130814_3 (AF130814) acetohydroxy acid isomerored... 153 3e-36
sp|O51888|ILVC_BUCAP KETOL-ACID REDUCTOISOMERASE (ACETOHYDROXY-A... 152 4e-36
sp|P44822|ILVC_HAEIN KETOL-ACID REDUCTOISOMERASE (ACETOHYDROXY-A... 151 9e-36
pir||G82356 ketol-acid reductoisomerase VC0162 [imported] - Vibr... 151 1e-35
gb|AAF13799.1|AF130812_3 (AF130812) acetohydroxy acid isomerored... 148 1e-34
sp|P57655|ILVC_BUCAI KETOL-ACID REDUCTOISOMERASE (ACETOHYDROXY-A... 139 3e-32
sp|O82043|ILV5_PEA KETOL-ACID REDUCTOISOMERASE PRECURSOR (ACETOH... 113 4e-24
pir||S36884 ketol-acid reductoisomerase (EC 1.1.1.86) - Arabidop... 111 1e-23
pir||S30145 ketol-acid reductoisomerase (EC 1.1.1.86) precursor ... 111 1e-23
sp|Q05758|ILV5_ARATH KETOL-ACID REDUCTOISOMERASE PRECURSOR (ACET... 109 4e-23
emb|CAB61890.1| (AJ251333) acetohydroxy acid isomeroreductase [P... 107 2e-22
sp|Q01292|ILV5_SPIOL KETOL-ACID REDUCTOISOMERASE PRECURSOR (ACET... 106 3e-22
pdb|1QMG|A Chain A, Acetohydroxyacid Isomeroreductase Complexed ... 106 3e-22
>pir||H75044 ketol-acid reductoisomerase (ilvc) PAB0889 - Pyrococcus abyssi
(strain Orsay) >gi|5458766|emb|CAB50253.1| (AJ248287)
ketol-acid reductoisomerase (ilvC) [Pyrococcus abyssi]
Length = 332
Score = 666 bits (1700), Expect = 0.0
Identities = 332/332 (100%), Positives = 332/332 (100%)
Query: 1 MVKVVKVYYDDEVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRA 60
MVKVVKVYYDDEVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRA
Sbjct: 1 MVKVVKVYYDDEVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRA 60
Query: 61 EKDGFEVYTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQI 120
EKDGFEVYTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQI
Sbjct: 61 EKDGFEVYTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQI 120
Query: 121 VPPEYVDVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRA 180
VPPEYVDVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRA
Sbjct: 121 VPPEYVDVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRA 180
Query: 181 GVIETTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMD 240
GVIETTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMD
Sbjct: 181 GVIETTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMD 240
Query: 241 LIYERGFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADK 300
LIYERGFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADK
Sbjct: 241 LIYERGFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADK 300
Query: 301 ASEVLEELMKPIEEHEIEKVGRFIRKMSGLER 332
ASEVLEELMKPIEEHEIEKVGRFIRKMSGLER
Sbjct: 301 ASEVLEELMKPIEEHEIEKVGRFIRKMSGLER 332
>sp|Q58938|ILVC_METJA KETOL-ACID REDUCTOISOMERASE (ACETOHYDROXY-ACID ISOMEROREDUCTASE)
(ALPHA-KETO-BETA-HYDROXYLACIL REDUCTOISOMERASE)
>gi|2129089|pir||F64492 ketol-acid reductoisomerase (EC
1.1.1.86) - Methanococcus jannaschii
>gi|1592174|gb|AAB99561.1| (U67595) ketol-acid
reductoisomerase (ilvC) [Methanococcus jannaschii]
Length = 348
Score = 406 bits (1032), Expect = e-112
Identities = 194/332 (58%), Positives = 258/332 (77%)
Query: 1 MVKVVKVYYDDEVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRA 60
++++VK++YD +V+ D +KDKT+AVIGYG+QG AQA NM+DSG++VI+GLRP+G+SW +A
Sbjct: 16 VIEMVKIFYDKDVTFDAVKDKTIAVIGYGSQGRAQALNMKDSGLNVIVGLRPNGASWNKA 75
Query: 61 EKDGFEVYTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQI 120
KDG +V TIEEA ++ADI+HILIPD VQP VY++ IEPYL EG+ + FSHG+NIHY I
Sbjct: 76 IKDGHKVMTIEEAAEKADIIHILIPDEVQPAVYKKQIEPYLTEGKTISFSHGYNIHYGFI 135
Query: 121 VPPEYVDVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRA 180
PPE V++ MVAPKSPG VR+ Y EGFGVP LVAV +DYTG+A +AL MAK IG T+
Sbjct: 136 RPPENVNITMVAPKSPGAMVRKTYEEGFGVPGLVAVERDYTGDALQIALGMAKGIGLTKV 195
Query: 181 GVIETTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMD 240
GVI+TTF++ETE+DL GEQ+VL GG+ ELIK FE LVE GY PE+AYFE C+E KLI+D
Sbjct: 196 GVIQTTFREETETDLFGEQVVLCGGVTELIKAAFETLVEAGYAPEMAYFETCHELKLIVD 255
Query: 241 LIYERGFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADK 300
LIY++G GM + VS+TA+YGGLT +VI++ ++ MK+ + ++ G FAKEW + +
Sbjct: 256 LIYQKGLQGMWENVSNTAEYGGLTRRARVINEESRKAMKEILKEIQDGRFAKEWSLEREA 315
Query: 301 ASEVLEELMKPIEEHEIEKVGRFIRKMSGLER 332
L L + +EH IEKVG+ +RKM GLE+
Sbjct: 316 GFPHLNALRRLEKEHLIEKVGKELRKMCGLEK 347
>pir||D72362 ketol-acid reductoisomerase - Thermotoga maritima (strain MSB8)
>gi|4981065|gb|AAD35635.1|AE001730_3 (AE001730)
ketol-acid reductoisomerase [Thermotoga maritima]
Length = 336
Score = 382 bits (971), Expect = e-105
Identities = 184/321 (57%), Positives = 240/321 (74%)
Query: 7 VYYDDEVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRAEKDGFE 66
+YYD + ++++KDK +A+IGYG+QG A A N++DSG++V++GLR SWK+AE+ G
Sbjct: 4 IYYDKDADLNLIKDKKIAIIGYGSQGHAHALNLKDSGLNVVVGLREGSKSWKKAEEQGLT 63
Query: 67 VYTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPPEYV 126
V TIEEA K ADI+ ILIPD QP++Y+++IE +L EG+ L F+HGFNIHY QI+PP+ V
Sbjct: 64 VKTIEEAAKEADIIMILIPDEHQPEIYKKYIEKHLTEGKMLMFAHGFNIHYHQIIPPKNV 123
Query: 127 DVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAGVIETT 186
DV M+APKSPG VR +Y+EG GVPALVAVYQDYTG AKD+ALA AK IG TRAGVIETT
Sbjct: 124 DVTMIAPKSPGHIVRREYVEGRGVPALVAVYQDYTGKAKDIALAYAKGIGVTRAGVIETT 183
Query: 187 FKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMDLIYERG 246
FK+ETE+DL GEQ VL GG+ LIK GFE LV+ GY PE+AYFE NE KLI+DLIYE G
Sbjct: 184 FKEETETDLFGEQAVLCGGVTALIKAGFETLVDAGYQPEIAYFECLNELKLIVDLIYEGG 243
Query: 247 FTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADKASEVLE 306
+ M +VS+TA+YG K++ V+ENMK+ + +++G+FAK+WI +
Sbjct: 244 LSFMRYSVSNTAEYGDYISQEKIVTKEVRENMKQMLKDIQTGKFAKDWILENQAGRPYFY 303
Query: 307 ELMKPIEEHEIEKVGRFIRKM 327
+ K EH IEKVG+ +RKM
Sbjct: 304 TMRKKESEHLIEKVGKELRKM 324
>sp|O27491|ILVC_METTH KETOL-ACID REDUCTOISOMERASE (ACETOHYDROXY-ACID ISOMEROREDUCTASE)
(ALPHA-KETO-BETA-HYDROXYLACIL REDUCTOISOMERASE)
>gi|7431340|pir||A69059 ketol-acid reductoisomerase -
Methanobacterium thermoautotrophicum (strain Delta H)
>gi|2622554|gb|AAB85917.1| (AE000905) ketol-acid
reductoisomerase [Methanobacterium thermoautotrophicum]
Length = 333
Score = 379 bits (963), Expect = e-104
Identities = 183/328 (55%), Positives = 242/328 (72%)
Query: 5 VKVYYDDEVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRAEKDG 64
+K+YY++++ M+IL DK +AVIGYG+QGEAQA+NM DSG++VI+GLR GSSWK+A DG
Sbjct: 6 MKIYYENDIDMEILADKKIAVIGYGSQGEAQARNMADSGLNVIVGLRRGGSSWKKAHDDG 65
Query: 65 FEVYTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPPE 124
V TIE+A + ADI+HILIPD +Q V+ + I PYL+EG + FSHG+NIHY I PE
Sbjct: 66 MNVMTIEDASREADIIHILIPDEIQETVFEQSIRPYLKEGNTISFSHGYNIHYGYIKAPE 125
Query: 125 YVDVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAGVIE 184
V+V MVAPK PG VR YLEGFG+P LVAV D TG+A + ALAMAKA G RAGV+E
Sbjct: 126 GVNVTMVAPKGPGAMVRRTYLEGFGIPGLVAVEVDATGDAMEQALAMAKACGLARAGVLE 185
Query: 185 TTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMDLIYE 244
TTF++ETE+DL GEQ VL GG+ ELI F+ LV GY PE+AYFE C+E KLI+DLIYE
Sbjct: 186 TTFREETETDLFGEQAVLCGGVTELINTAFKTLVRAGYQPEIAYFETCHELKLIVDLIYE 245
Query: 245 RGFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADKASEV 304
RGF GM VS+TA++GGLT ++I + ++ M + + +++G+FAKEW + + +
Sbjct: 246 RGFRGMWHNVSNTAEFGGLTRRGRIITEETEKEMDEILKEIQNGKFAKEWALENRAGAPM 305
Query: 305 LEELMKPIEEHEIEKVGRFIRKMSGLER 332
L+ + K E EIE+VG +RK+ GLE+
Sbjct: 306 LKRMRKLESELEIEEVGSKLRKLCGLEK 333
>sp|O67289|ILVC_AQUAE KETOL-ACID REDUCTOISOMERASE (ACETOHYDROXY-ACID ISOMEROREDUCTASE)
(ALPHA-KETO-BETA-HYDROXYLACIL REDUCTOISOMERASE)
>gi|7431342|pir||F70407 acetohydroxy acid
isomeroreductase - Aquifex aeolicus
>gi|2983675|gb|AAC07240.1| (AE000730) acetohydroxy acid
isomeroreductase [Aquifex aeolicus]
Length = 333
Score = 376 bits (955), Expect = e-103
Identities = 186/324 (57%), Positives = 236/324 (72%), Gaps = 1/324 (0%)
Query: 4 VVKVYYDDEVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRAEKD 63
+ K+YYD++ S+DILKDK +A++GYG+QG A A N+RDSG++VI+GL S ++A+ D
Sbjct: 1 MAKIYYDEDASLDILKDKVIAILGYGSQGHAHALNLRDSGLNVIIGLHEGSRSREKAKAD 60
Query: 64 GFEVYTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPP 123
GFEVYT EA KRADI+ LIPD VQP+VY+ +EP L + L F+HGFNIH++QIVPP
Sbjct: 61 GFEVYTPREAAKRADIIMFLIPDTVQPEVYKNEVEPELNSSKTLAFAHGFNIHFRQIVPP 120
Query: 124 EYVDVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAGVI 183
+ VDV MVAPK PG VR Y EG GVPALVA++QD +G KD ALA AK IG TRAGVI
Sbjct: 121 KDVDVFMVAPKGPGHLVRWMYTEGKGVPALVAIHQDASGTCKDKALAYAKGIGATRAGVI 180
Query: 184 ETTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMDLIY 243
ETTFK+ETE+DL GEQ+VL GG+ LIK GFE LV GY PE+AYFE +E KLI+DLIY
Sbjct: 181 ETTFKEETETDLFGEQMVLCGGVTALIKAGFETLVNAGYQPEVAYFECLHELKLIVDLIY 240
Query: 244 ERGFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADKASE 303
E G +GM ++SDTAKYG +T G ++ VK M+K E ++ GEFA+EWI +
Sbjct: 241 EHGISGMRYSISDTAKYGDVTRGERIY-KVVKPVMEKTLEEIQKGEFAREWILENKAGRP 299
Query: 304 VLEELMKPIEEHEIEKVGRFIRKM 327
V L++ EH +EKVG +RKM
Sbjct: 300 VYYALLERDREHLVEKVGEELRKM 323
>gi|11499567 ketol-acid reductoisomerase (ilvC) [Archaeoglobus fulgidus]
>gi|6225545|sp|O28294|ILVC_ARCFU KETOL-ACID
REDUCTOISOMERASE (ACETOHYDROXY-ACID ISOMEROREDUCTASE)
(ALPHA-KETO-BETA-HYDROXYLACIL REDUCTOISOMERASE)
>gi|7431341|pir||H69497 ketol-acid reductoisomerase
(ilvC) homolog - Archaeoglobus fulgidus
>gi|2648554|gb|AAB89269.1| (AE000966) ketol-acid
reductoisomerase (ilvC) [Archaeoglobus fulgidus]
Length = 332
Score = 369 bits (936), Expect = e-101
Identities = 181/325 (55%), Positives = 235/325 (71%), Gaps = 1/325 (0%)
Query: 4 VVKVYYDDEVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRP-SGSSWKRAEK 62
+ K+Y D + + L KTV +IGYG+QG A A N++DSGV+V++GL ++W+RAEK
Sbjct: 1 MAKIYRDADADLKYLDGKTVCIIGYGSQGHAHALNLKDSGVNVVVGLPEWDKATWERAEK 60
Query: 63 DGFEVYTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVP 122
DG V + EA AD++ +LIPD+VQP VYREHI+ L+EG L F+HGFNIHY QIVP
Sbjct: 61 DGMVVKKLSEAADGADVIAMLIPDMVQPAVYREHIQDKLKEGAMLMFAHGFNIHYNQIVP 120
Query: 123 PEYVDVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAGV 182
PEYVDV MVAPK PG VR Y+EG GVP+LVAV Q+YTG A ++ALA AK IG TRAGV
Sbjct: 121 PEYVDVAMVAPKGPGPLVRRMYVEGKGVPSLVAVEQNYTGKALEVALAYAKGIGATRAGV 180
Query: 183 IETTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMDLI 242
IETTFK+ETE+DL GEQ+ L GG+ E+IK FE LVE GY PE+AYFE +E KLI+DLI
Sbjct: 181 IETTFKEETETDLFGEQVDLCGGVAEMIKMSFETLVEAGYQPEIAYFEVLHELKLIVDLI 240
Query: 243 YERGFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADKAS 302
YE G M AVS+TAKYGG+T G ++ + +E M+K + +++GEFA+EWI +
Sbjct: 241 YEGGIYNMWSAVSETAKYGGMTRGKRIFTEQTREEMRKILKEIQTGEFAREWILENMAGR 300
Query: 303 EVLEELMKPIEEHEIEKVGRFIRKM 327
V +L++ EH IEK+G+ +R M
Sbjct: 301 PVYNKLLQMEREHPIEKIGKELRAM 325
>gb|AAK40890.1| Ketol-acid reductoisomerase (ilvC-1) [Sulfolobus solfataricus]
Length = 335
Score = 358 bits (909), Expect = 5e-98
Identities = 168/322 (52%), Positives = 239/322 (74%)
Query: 6 KVYYDDEVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRAEKDGF 65
K+Y D++ ++D++K K +AV+GYG+QG A A+N+RDSG++V++GL G SW+ A+ DG
Sbjct: 6 KIYTDNDANLDLIKGKRIAVLGYGSQGRAWAQNLRDSGLNVVVGLEREGKSWELAKSDGI 65
Query: 66 EVYTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPPEY 125
++AVK ADI+ L+PD+VQ ++ E ++PY+++G L F+HGFNIHYK I PP+
Sbjct: 66 TPLHTKDAVKDADIIIFLVPDMVQRTLWLESVQPYMKKGADLVFAHGFNIHYKLIDPPKD 125
Query: 126 VDVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAGVIET 185
DV M+APK PG VRE Y G GVPALVAV+QD +G A ALA+AK IG TRAGVI T
Sbjct: 126 SDVYMIAPKGPGPTVREYYKAGGGVPALVAVHQDVSGTALHKALAIAKGIGATRAGVIPT 185
Query: 186 TFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMDLIYER 245
TFK+ETE+DL GEQ++LVGG++EL++ FE LVE GY PE+AYFE NE K+++DL+YE+
Sbjct: 186 TFKEETETDLFGEQVILVGGIMELMRAAFETLVEEGYQPEVAYFETINELKMLVDLVYEK 245
Query: 246 GFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADKASEVL 305
G +GMLKAVSDTAKYGG+TVG VID+ V++ MK+ +R++SG+FA+EW+ + + +
Sbjct: 246 GISGMLKAVSDTAKYGGMTVGKFVIDESVRKRMKEALQRIKSGKFAEEWVEEYGRGMPTV 305
Query: 306 EELMKPIEEHEIEKVGRFIRKM 327
+ ++ EK+G +R +
Sbjct: 306 VNGLSNVQNSLEEKIGNQLRDL 327
>emb|CAB57724.1| (Y18930) ketol-acid reductoisomerase [Sulfolobus solfataricus]
Length = 335
Score = 358 bits (909), Expect = 5e-98
Identities = 168/322 (52%), Positives = 239/322 (74%)
Query: 6 KVYYDDEVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRAEKDGF 65
K+Y D++ ++D++K K +AV+GYG+QG A A+N+RDSG++V++GL G SW+ A+ DG
Sbjct: 6 KIYTDNDANLDLIKGKRIAVLGYGSQGRAWAQNLRDSGLNVVVGLEREGKSWELAKSDGI 65
Query: 66 EVYTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPPEY 125
++AVK ADI+ L+PD+VQ ++ E ++PY+++G L F+HGFNIHYK I PP+
Sbjct: 66 TPLHTKDAVKDADIIIFLVPDMVQRTLWLESVQPYMKKGADLVFAHGFNIHYKLIDPPKD 125
Query: 126 VDVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAGVIET 185
DV M+APK PG VRE Y G GVPALVAV+QD +G A ALA+AK IG TRAGVI T
Sbjct: 126 SDVYMIAPKGPGPTVREYYKAGGGVPALVAVHQDVSGTALHKALAIAKGIGATRAGVIPT 185
Query: 186 TFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMDLIYER 245
TFK+ETE+DL GEQ++LVGG++EL++ FE LVE GY PE+AYFE NE K+++DL+YE+
Sbjct: 186 TFKEETETDLFGEQVILVGGIMELMRAAFETLVEEGYQPEVAYFETINELKMLVDLVYEK 245
Query: 246 GFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADKASEVL 305
G +GMLKAVSDTAKYGG+TVG VID+ V++ MK+ +R++SG+FA+EW+ + + +
Sbjct: 246 GISGMLKAVSDTAKYGGMTVGKFVIDESVRKRMKEALQRIKSGKFAEEWVEEYGRGMPTV 305
Query: 306 EELMKPIEEHEIEKVGRFIRKM 327
+ ++ EK+G +R +
Sbjct: 306 VNGLSNVQNSLEEKIGNQLRDL 327
>dbj|BAB06778.1| (AP001517) ketol-acid reductoisomerase [Bacillus halodurans]
Length = 340
Score = 350 bits (888), Expect = 1e-95
Identities = 170/324 (52%), Positives = 227/324 (69%), Gaps = 1/324 (0%)
Query: 4 VVKVYYDDEVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRAEKD 63
+ KV+Y+ +++ +L+ KTVA+IGYG+QG A A+N+RDSG VI+GLRP G SW +A +D
Sbjct: 1 MAKVFYNGDINEGVLQGKTVAIIGYGSQGHAHAQNLRDSGQEVIVGLRP-GKSWDKAAED 59
Query: 64 GFEVYTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPP 123
GF+VY++ EA RAD++ IL+PD QP VY+ IEP L EG+ L F+HGFN+H+ QIVPP
Sbjct: 60 GFQVYSVREAASRADVIMILLPDEHQPTVYKNEIEPELSEGKTLAFAHGFNVHFNQIVPP 119
Query: 124 EYVDVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAGVI 183
VDV + APK PG VR Y++G GVP LVAVYQD TG AKD+ALA +K G RAGVI
Sbjct: 120 ATVDVFLAAPKGPGHLVRRTYVDGAGVPGLVAVYQDATGQAKDIALAYSKMNGSARAGVI 179
Query: 184 ETTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMDLIY 243
ETTF++ETE+DL GEQ VL GG L+K GFE LVE GY PE+AYFE +E KLI+DL+Y
Sbjct: 180 ETTFQEETETDLFGEQAVLCGGTSALVKAGFETLVEAGYQPEVAYFECLHELKLIVDLMY 239
Query: 244 ERGFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADKASE 303
E G M ++SDTA++G GP+V+ K+ MK +++G+FAK WI +
Sbjct: 240 EGGLEYMRYSISDTAQWGDFQAGPRVVTAETKQAMKDILSDIQTGKFAKGWILENQANRP 299
Query: 304 VLEELMKPIEEHEIEKVGRFIRKM 327
+ + + H +E VGR +R+M
Sbjct: 300 EFTAINEREKNHPLEVVGRELREM 323
>sp|P37253|ILVC_BACSU KETOL-ACID REDUCTOISOMERASE (ACETOHYDROXY-ACID ISOMEROREDUCTASE)
(ALPHA-KETO-BETA-HYDROXYLACIL REDUCTOISOMERASE)
>gi|7431339|pir||C69644 ketol-acid reductoisomerase ilvC
- Bacillus subtilis >gi|143093|gb|AAA22548.1| (L03181)
ketol-acid reductoisomerase [Bacillus subtilis]
>gi|1770068|emb|CAA99563.1| (Z75208) ketol-acid
reductoisomerase [Bacillus subtilis]
>gi|2635294|emb|CAB14789.1| (Z99118) ketol-acid
reductoisomerase (acetohydroxy-acid isomeroreductase)
[Bacillus subtilis]
Length = 342
Score = 345 bits (875), Expect = 5e-94
Identities = 171/324 (52%), Positives = 231/324 (70%), Gaps = 1/324 (0%)
Query: 4 VVKVYYDDEVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRAEKD 63
+VKVYY+ ++ ++L KTVAVIGYG+QG A A N+++SGV VI+G+R G S+ +A++D
Sbjct: 1 MVKVYYNGDIKENVLAGKTVAVIGYGSQGHAHALNLKESGVDVIVGVR-QGKSFTQAQED 59
Query: 64 GFEVYTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPP 123
G +V++++EA +A+I+ +L+PD Q KVY I+ L G++L F+HGFN+H+ QIVPP
Sbjct: 60 GHKVFSVKEAAAQAEIIMVLLPDEQQQKVYEAEIKDELTAGKSLVFAHGFNVHFHQIVPP 119
Query: 124 EYVDVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAGVI 183
VDV +VAPK PG VR Y +G GVPAL A+YQD TG A+D ALA AK IG RAGV+
Sbjct: 120 ADVDVFLVAPKGPGHLVRRTYEQGAGVPALFAIYQDVTGEARDKALAYAKGIGGARAGVL 179
Query: 184 ETTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMDLIY 243
ETTFK+ETE+DL GEQ VL GGL L+K GFE L E GY PELAYFE +E KLI+DL+Y
Sbjct: 180 ETTFKEETETDLFGEQAVLCGGLSALVKAGFETLTEAGYQPELAYFECLHELKLIVDLMY 239
Query: 244 ERGFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADKASE 303
E G GM ++SDTA++G GP+V+D VKE+MK+ + +++G FAKEWI +
Sbjct: 240 EEGLAGMRYSISDTAQWGDFVSGPRVVDAKVKESMKEVLKDIQNGTFAKEWIVENQVNRP 299
Query: 304 VLEELMKPIEEHEIEKVGRFIRKM 327
+ EH+IE VGR +R+M
Sbjct: 300 RFNAINASENEHQIEVVGRKLREM 323
>pir||C75387 ketol-acid reductoisomerase - Deinococcus radiodurans (strain R1)
>gi|6459279|gb|AAF11083.1|AE001995_8 (AE001995)
ketol-acid reductoisomerase [Deinococcus radiodurans]
Length = 363
Score = 344 bits (872), Expect = 1e-93
Identities = 162/320 (50%), Positives = 225/320 (69%)
Query: 6 KVYYDDEVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRAEKDGF 65
K+YYD +V +L++K +A+IGYG+Q A A+N+RDSG +V++GLR SS +AE+ G
Sbjct: 31 KMYYDRDVDTQVLENKLIAIIGYGSQAHAHAQNLRDSGFNVVVGLREGSSSKAKAEQAGL 90
Query: 66 EVYTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPPEY 125
V +IE+A K AD+V +LIPD QP VY + I P+L G+AL F HGFN+H+ +I PP
Sbjct: 91 RVASIEDATKEADVVMLLIPDEQQPAVYEKSIAPHLTAGKALAFGHGFNVHFGRIKPPAD 150
Query: 126 VDVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAGVIET 185
VDV +VAPK PG +R Y +G G+P + AV QD +G A+D+ALA A+ IGCT+AGV+ET
Sbjct: 151 VDVFLVAPKGPGHMLRRVYTDGAGMPGIFAVQQDASGKARDIALAYARGIGCTKAGVLET 210
Query: 186 TFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMDLIYER 245
TFK+ETE+DL GEQ VL GG+ LI+ GFE LVE GY PE+AYFE +E KLI+DLIYE+
Sbjct: 211 TFKEETETDLFGEQSVLCGGVTHLIQAGFETLVEAGYQPEIAYFETLHEVKLIVDLIYEK 270
Query: 246 GFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADKASEVL 305
GF GM ++S+TA++G GP++I D K MK ++SG+FA+ +I A+ +
Sbjct: 271 GFEGMRHSISNTAEFGDYVTGPRIITDQTKAEMKNVLGDIQSGKFAESFIKDAESGFPYM 330
Query: 306 EELMKPIEEHEIEKVGRFIR 325
E + +H +EKVG+ +R
Sbjct: 331 NEQRSKMRDHTVEKVGKELR 350
>pir||F81066 ketol-acid reductoisomerase NMB1574 [imported] - Neisseria
meningitidis (group B strain MD58)
>gi|7226822|gb|AAF41927.1| (AE002508) ketol-acid
reductoisomerase [Neisseria meningitidis MC58]
Length = 337
Score = 338 bits (858), Expect = 5e-92
Identities = 165/323 (51%), Positives = 226/323 (69%), Gaps = 1/323 (0%)
Query: 5 VKVYYDDEVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRAEKDG 64
++VYYD + + ++K KTVA+IGYG+QG A A N++DSGV+V++GLR GSSWK+AE G
Sbjct: 1 MQVYYDKDADLSLIKGKTVAIIGYGSQGHAHAANLKDSGVNVVIGLR-QGSSWKKAEAAG 59
Query: 65 FEVYTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPPE 124
V T+ EA K AD+V +L+PD P VY + L+EG L F+HGFN+HY QIVP
Sbjct: 60 HVVKTVAEATKEADVVMLLLPDETMPAVYHAEVTANLKEGATLAFAHGFNVHYNQIVPRA 119
Query: 125 YVDVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAGVIE 184
+DVIMVAPK PG VR +Y G GVP+L+AVYQD +G AKD+AL+ A A G T+ GVIE
Sbjct: 120 DLDVIMVAPKGPGHTVRSEYKRGGGVPSLIAVYQDNSGKAKDIALSYAAANGGTKGGVIE 179
Query: 185 TTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMDLIYE 244
TTF++ETE+DL GEQ VL GG++ELIK GFE L E GY PE+AYFE +E KLI+DLI+E
Sbjct: 180 TTFREETETDLFGEQAVLCGGVVELIKAGFETLTEAGYAPEMAYFECLHEMKLIVDLIFE 239
Query: 245 RGFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADKASEV 304
G M ++S+ A+YG GP+V++ KE M+ +R+++GE+AK +I + +
Sbjct: 240 GGIANMNYSISNNAEYGEYVTGPEVVNASSKEAMRNALKRIQTGEYAKMFIQEGNVNYAS 299
Query: 305 LEELMKPIEEHEIEKVGRFIRKM 327
+ + +H++EKVG +R M
Sbjct: 300 MTARRRLNADHQVEKVGAQLRAM 322
>pir||C81801 ketol-acid reductoisomerase (EC 1.1.1.86) NMA1763 [imported] -
Neisseria meningitidis (group A strain Z2491)
>gi|7380405|emb|CAB84991.1| (AL162757) ketol-acid
reductoisomerase [Neisseria meningitidis Z2491]
Length = 337
Score = 338 bits (858), Expect = 5e-92
Identities = 165/323 (51%), Positives = 226/323 (69%), Gaps = 1/323 (0%)
Query: 5 VKVYYDDEVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRAEKDG 64
++VYYD + + ++K KTVA+IGYG+QG A A N++DSGV+V++GLR GSSWK+AE G
Sbjct: 1 MQVYYDKDADLSLIKGKTVAIIGYGSQGHAHAANLKDSGVNVVIGLR-QGSSWKKAEAAG 59
Query: 65 FEVYTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPPE 124
V T+ EA K AD+V +L+PD P VY + L+EG L F+HGFN+HY QIVP
Sbjct: 60 HVVKTVAEATKEADVVMLLLPDETMPAVYHAEVAANLKEGATLAFAHGFNVHYNQIVPRA 119
Query: 125 YVDVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAGVIE 184
+DVIMVAPK PG VR +Y G GVP+L+AVYQD +G AKD+AL+ A A G T+ GVIE
Sbjct: 120 DLDVIMVAPKGPGHTVRSEYKRGGGVPSLIAVYQDNSGKAKDIALSYAAANGGTKGGVIE 179
Query: 185 TTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMDLIYE 244
TTF++ETE+DL GEQ VL GG++ELIK GFE L E GY PE+AYFE +E KLI+DLI+E
Sbjct: 180 TTFREETETDLFGEQAVLCGGVVELIKAGFETLTEAGYAPEMAYFECLHEMKLIVDLIFE 239
Query: 245 RGFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADKASEV 304
G M ++S+ A+YG GP+V++ KE M+ +R+++GE+AK +I + +
Sbjct: 240 GGIANMNYSISNNAEYGEYVTGPEVVNASSKEAMRNALKRIQTGEYAKMFIQEGNVNYAS 299
Query: 305 LEELMKPIEEHEIEKVGRFIRKM 327
+ + +H++EKVG +R M
Sbjct: 300 MTARRRLNADHQVEKVGAQLRAM 322
>gb|AAD32178.1|AF125563_3 (AF125563) ketol-acid reductoisomerase [Neisseria meningitidis]
Length = 337
Score = 337 bits (856), Expect = 8e-92
Identities = 165/323 (51%), Positives = 225/323 (69%), Gaps = 1/323 (0%)
Query: 5 VKVYYDDEVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRAEKDG 64
++VYYD + + ++K KTVA+IGYG+QG A A N++DSGV+V++GLR GSSWK+AE G
Sbjct: 1 MQVYYDKDADLSLIKGKTVAIIGYGSQGHAHAANLKDSGVNVVIGLR-QGSSWKKAEAAG 59
Query: 65 FEVYTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPPE 124
V T+ EA K AD+V +L+PD P VY + L+EG L F+HGFN+HY QIVP
Sbjct: 60 HVVKTVAEATKEADVVMLLLPDETMPAVYHAEVTANLKEGATLAFAHGFNVHYNQIVPRA 119
Query: 125 YVDVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAGVIE 184
+DVIMVAPK PG VR +Y G GVP+L+AVYQD +G AKD+AL+ A A G T+ GVIE
Sbjct: 120 DLDVIMVAPKGPGHTVRSEYKRGGGVPSLIAVYQDNSGKAKDIALSYAAANGGTKGGVIE 179
Query: 185 TTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMDLIYE 244
TTF++ETE+DL GEQ VL GG++ELIK GFE L E GY PE+AYFE +E KLI+DLI+E
Sbjct: 180 TTFREETETDLFGEQAVLCGGVVELIKAGFETLTEAGYAPEMAYFECLHEMKLIVDLIFE 239
Query: 245 RGFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADKASEV 304
G M ++S+ A+YG GP+V++ KE M+ +R+++GE+AK +I +
Sbjct: 240 GGIANMNYSISNNAEYGEYVTGPEVVNASSKEAMRNALKRIQTGEYAKMFIQEGGVNYAS 299
Query: 305 LEELMKPIEEHEIEKVGRFIRKM 327
+ + +H++EKVG +R M
Sbjct: 300 MTARRRLNADHQVEKVGAQLRAM 322
>gb|AAG39032.1|AF220670_3 (AF220670) alpha-keto-beta-hydroxylacil reductoisomerase
[Streptococcus thermophilus]
Length = 340
Score = 330 bits (836), Expect = 2e-89
Identities = 165/322 (51%), Positives = 221/322 (68%), Gaps = 1/322 (0%)
Query: 5 VKVYYDDEVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRAEKDG 64
V++ Y+ +V + L K +AVIGYG+QG A ++N+RD+G VI+G+RP G S+ +A++DG
Sbjct: 3 VQMEYEKDVKVPALDGKKIAVIGYGSQGHAHSQNLRDTGHDVIIGVRP-GKSFDKAKEDG 61
Query: 65 FEVYTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPPE 124
F+ YT+ EA K AD++ IL PD +Q ++Y I P L G A+GF+HGFNIH++ I P
Sbjct: 62 FDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGNAVGFAHGFNIHFEFIKVPA 121
Query: 125 YVDVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAGVIE 184
VDV M APK PG VR + EGFGVPAL AVYQD TGNAKD+A+ K IG R G++E
Sbjct: 122 DVDVFMCAPKGPGHLVRRTFEEGFGVPALYAVYQDATGNAKDIAMDWCKGIGAARVGLLE 181
Query: 185 TTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMDLIYE 244
TT+K+ETE DL GEQ VL GGL LI+ GFEVL E GY PELAYFE +E KLI+DLIYE
Sbjct: 182 TTYKEETEEDLFGEQAVLCGGLTALIETGFEVLTEAGYAPELAYFEVLHEMKLIVDLIYE 241
Query: 245 RGFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADKASEV 304
GF M +++S+TA++G GP+VI + VKENMK +++G+FA ++++
Sbjct: 242 GGFKKMRQSISNTAEFGDYVSGPRVITEQVKENMKAVLADIQNGKFANDFVNDYKAGRPK 301
Query: 305 LEELMKPIEEHEIEKVGRFIRK 326
L + EIEKVG +RK
Sbjct: 302 LTAYREEAANLEIEKVGAELRK 323
>sp|Q02138|ILVC_LACLA KETOL-ACID REDUCTOISOMERASE (ACETOHYDROXY-ACID ISOMEROREDUCTASE)
(ALPHA-KETO-BETA-HYDROXYLACIL REDUCTOISOMERASE)
>gi|486732|pir||S35140 probable ketol-acid
reductoisomerase (EC 1.1.1.86) - Lactococcus lactis
subsp. lactis >gi|2565159|gb|AAB81921.1| (U92974) IlvC
[Lactococcus lactis]
Length = 344
Score = 329 bits (835), Expect = 2e-89
Identities = 160/317 (50%), Positives = 222/317 (69%), Gaps = 1/317 (0%)
Query: 5 VKVYYDDEVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRAEKDG 64
V +YY+D+V + L K +AVIGYG+QG A A+N+RDSG +VI+G+R G S+ +A++DG
Sbjct: 3 VTMYYEDDVEVSALAGKQIAVIGYGSQGHAHAQNLRDSGHNVIIGVR-HGKSFDKAKEDG 61
Query: 65 FEVYTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPPE 124
FE + + EAV +AD++ +L PD +Q +Y E I+P L+ G ALGF+HGFNIH+ I PE
Sbjct: 62 FETFEVGEAVAKADVIMVLAPDELQQSIYEEDIKPNLKAGSALGFAHGFNIHFGYIKVPE 121
Query: 125 YVDVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAGVIE 184
VDV MVAPK+PG VR Y EGFG PAL +Q+ +G+A+++A+ AK IGC R G+IE
Sbjct: 122 DVDVFMVAPKAPGHLVRRTYTEGFGTPALFVSHQNASGHAREIAMDWAKGIGCARVGIIE 181
Query: 185 TTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMDLIYE 244
TTFK+ETE DL GEQ VL GGL L++ GFE L E GY ELAYFE +E KLI+DL+YE
Sbjct: 182 TTFKEETEEDLFGEQAVLCGGLTALVEAGFETLTEAGYAGELAYFEVLHEMKLIVDLMYE 241
Query: 245 RGFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADKASEV 304
GFT M +++S+TA++G GP++I D VK+NMK ++SG+FA++++
Sbjct: 242 GGFTKMRQSISNTAEFGDYVTGPRIITDEVKKNMKLVLADIQSGKFAQDFVDDFKAGRPK 301
Query: 305 LEELMKPIEEHEIEKVG 321
L + + EIEK+G
Sbjct: 302 LIAYREAAKNLEIEKIG 318
>pir||A47037 ketol-acid reductoisomerase (EC 1.1.1.86) - Synechocystis sp.
(strain PCC 6803) >gi|1653755|dbj|BAA18666.1| (D90916)
ketol-acid reductoisomerase [Synechocystis sp.]
Length = 367
Score = 329 bits (835), Expect = 2e-89
Identities = 162/324 (50%), Positives = 223/324 (68%)
Query: 4 VVKVYYDDEVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRAEKD 63
+ ++YYD + ++D+L KTVA+IGYG+QG A A N++DSGV+V++GL S +AE
Sbjct: 37 MARMYYDQDANLDLLAGKTVAIIGYGSQGHAHALNLKDSGVNVVVGLYSGSKSVAKAEGA 96
Query: 64 GFEVYTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPP 123
G +V ++ EA K AD++ IL+PD VQ VY I P L G L F+HGFNI++ QIVPP
Sbjct: 97 GLKVLSVAEAAKAADLIMILLPDEVQKTVYEAEIAPNLVAGNVLLFAHGFNINFAQIVPP 156
Query: 124 EYVDVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAGVI 183
VDV+M APK PG VR Y +G GVPAL AVYQD +G A+D A+A AK IG TRAG++
Sbjct: 157 ADVDVVMAAPKGPGHLVRRTYEQGQGVPALFAVYQDASGQARDYAMAYAKGIGGTRAGIL 216
Query: 184 ETTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMDLIY 243
ETTF++ETE+DL GEQ+VL GGL LIK GF+ LVE GY PELAYFE +E KLI+DLI
Sbjct: 217 ETTFREETETDLFGEQVVLCGGLTALIKAGFDTLVEAGYQPELAYFECLHEVKLIVDLIV 276
Query: 244 ERGFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADKASE 303
E G M ++S+TA+YG LT GP+++ + K M++ + ++SG+FA+E++ +
Sbjct: 277 EGGLAKMRDSISNTAEYGDLTRGPRIVTEETKAEMRQILDEIQSGQFAREFVLENQAGKP 336
Query: 304 VLEELMKPIEEHEIEKVGRFIRKM 327
+ + E IE+VG+ +R M
Sbjct: 337 GFTAMRRRESEELIEEVGKDLRAM 360
>sp|P29107|ILVC_SYNY3 KETOL-ACID REDUCTOISOMERASE (ACETOHYDROXY-ACID ISOMEROREDUCTASE)
(ALPHA-KETO-BETA-HYDROXYLACIL REDUCTOISOMERASE)
Length = 331
Score = 329 bits (835), Expect = 2e-89
Identities = 162/324 (50%), Positives = 223/324 (68%)
Query: 4 VVKVYYDDEVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRAEKD 63
+ ++YYD + ++D+L KTVA+IGYG+QG A A N++DSGV+V++GL S +AE
Sbjct: 1 MARMYYDQDANLDLLAGKTVAIIGYGSQGHAHALNLKDSGVNVVVGLYSGSKSVAKAEGA 60
Query: 64 GFEVYTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPP 123
G +V ++ EA K AD++ IL+PD VQ VY I P L G L F+HGFNI++ QIVPP
Sbjct: 61 GLKVLSVAEAAKAADLIMILLPDEVQKTVYEAEIAPNLVAGNVLLFAHGFNINFAQIVPP 120
Query: 124 EYVDVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAGVI 183
VDV+M APK PG VR Y +G GVPAL AVYQD +G A+D A+A AK IG TRAG++
Sbjct: 121 ADVDVVMAAPKGPGHLVRRTYEQGQGVPALFAVYQDASGQARDYAMAYAKGIGGTRAGIL 180
Query: 184 ETTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMDLIY 243
ETTF++ETE+DL GEQ+VL GGL LIK GF+ LVE GY PELAYFE +E KLI+DLI
Sbjct: 181 ETTFREETETDLFGEQVVLCGGLTALIKAGFDTLVEAGYQPELAYFECLHEVKLIVDLIV 240
Query: 244 ERGFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADKASE 303
E G M ++S+TA+YG LT GP+++ + K M++ + ++SG+FA+E++ +
Sbjct: 241 EGGLAKMRDSISNTAEYGDLTRGPRIVTEETKAEMRQILDEIQSGQFAREFVLENQAGKP 300
Query: 304 VLEELMKPIEEHEIEKVGRFIRKM 327
+ + E IE+VG+ +R M
Sbjct: 301 GFTAMRRRESEELIEEVGKDLRAM 324
>pir||G81411 ketol-acid reductoisomerase (EC 1.1.1.86) Cj0632 [imported] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6968099|emb|CAB75268.1| (AL139075) ketol-acid
reductoisomerase [Campylobacter jejuni]
Length = 340
Score = 318 bits (807), Expect = 5e-86
Identities = 159/323 (49%), Positives = 221/323 (68%)
Query: 5 VKVYYDDEVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRAEKDG 64
+ VYYD + ++++K K VA+IG+G+QG A A N+RD+GV+V +GLR S +A+ G
Sbjct: 3 ITVYYDKDCDLNLIKSKKVAIIGFGSQGHAHAMNLRDNGVNVTIGLREGSVSAVKAKNAG 62
Query: 65 FEVYTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPPE 124
FEV ++ EA K AD++ IL PD +Q ++ I+P L EG+A+ F+HGFNIHY QIV P+
Sbjct: 63 FEVVSVSEASKIADVIMILAPDEIQADIFNVEIKPNLSEGKAIAFAHGFNIHYGQIVVPK 122
Query: 125 YVDVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAGVIE 184
VDVIM+APK+PG VR ++ G G P L+A++QD + NAK+LAL+ A AIG R G+IE
Sbjct: 123 GVDVIMIAPKAPGHTVRNEFTLGGGTPCLIAIHQDESKNAKNLALSYASAIGGGRTGIIE 182
Query: 185 TTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMDLIYE 244
TTFK ETE+DL GEQ VL GGL LI+ GFE LVE GY PE+AYFE +E KLI+DLIY+
Sbjct: 183 TTFKAETETDLFGEQAVLCGGLSALIQAGFETLVEAGYEPEMAYFECLHEMKLIVDLIYQ 242
Query: 245 RGFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADKASEV 304
G M ++S+TA+YG GPK+I + K+ MK + +++G FAK++I +
Sbjct: 243 GGIADMRYSISNTAEYGDYITGPKIITEETKKAMKGVLKDIQNGVFAKDFILERRAGFAR 302
Query: 305 LEELMKPIEEHEIEKVGRFIRKM 327
+ K + + IEK GR +R M
Sbjct: 303 MHAERKNMNDSLIEKTGRNLRAM 325
>pir||E83059 ketol-acid reductoisomerase PA4694 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9950951|gb|AAG08080.1|AE004883_4 (AE004883)
ketol-acid reductoisomerase [Pseudomonas aeruginosa]
Length = 338
Score = 315 bits (799), Expect = 4e-85
Identities = 152/323 (47%), Positives = 222/323 (68%)
Query: 5 VKVYYDDEVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRAEKDG 64
++V+YD + + I++ K VA+IGYG+QG A A N++DSGV V +GLR ++ +AE G
Sbjct: 1 MRVFYDKDCDLSIIQGKKVAIIGYGSQGHAHACNLKDSGVDVTVGLRSGSATVAKAEAHG 60
Query: 65 FEVYTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPPE 124
+V ++ AV AD+V IL PD Q ++Y+E IEP L++G L F+HGF+IHY Q+VP
Sbjct: 61 LKVADVKTAVAAADVVMILTPDEFQGRLYKEEIEPNLKKGATLAFAHGFSIHYNQVVPRA 120
Query: 125 YVDVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAGVIE 184
+DVIM+APK+PG VR ++++G G+P L+A+YQD +GNAK++AL+ A +G R G+IE
Sbjct: 121 DLDVIMIAPKAPGHTVRSEFVKGGGIPDLIAIYQDASGNAKNVALSYACGVGGGRTGIIE 180
Query: 185 TTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMDLIYE 244
TTFKDETE+DL GEQ VL GG +EL+K GFE LVE GY PE+AYFE +E KLI+DL+YE
Sbjct: 181 TTFKDETETDLFGEQAVLCGGCVELVKAGFETLVEAGYAPEMAYFECLHELKLIVDLMYE 240
Query: 245 RGFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADKASEV 304
G M ++S+ A+YG GP+VI+ + M+ +R++ GE+AK +I++
Sbjct: 241 GGIANMNYSISNNAEYGEYVTGPEVINAESRAAMRNALKRIQDGEYAKMFITEGAANYPS 300
Query: 305 LEELMKPIEEHEIEKVGRFIRKM 327
+ + H IE++G +R M
Sbjct: 301 MTAYRRNNAAHPIEQIGEKLRAM 323
>sp|Q59500|ILVC_MYCAV KETOL-ACID REDUCTOISOMERASE (ACETOHYDROXY-ACID ISOMEROREDUCTASE)
(ALPHA-KETO-BETA-HYDROXYLACIL REDUCTOISOMERASE)
>gi|2127452|pir||JC5166 ketol-acid reductoisomerase (EC
1.1.1.86) - Mycobacterium avium
>gi|1196509|gb|AAB38428.1| (L49392) acetohydroxy acid
isomeroreductase [Mycobacterium avium]
Length = 333
Score = 315 bits (798), Expect = 5e-85
Identities = 159/327 (48%), Positives = 221/327 (66%), Gaps = 1/327 (0%)
Query: 7 VYYDDEVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRAEKDGFE 66
++YDD+ + I++ + V VIGYG+QG A + ++RDSGV V +GL+ S + + G +
Sbjct: 1 MFYDDDADLTIIQGRKVGVIGYGSQGHAHSLSLRDSGVQVKVGLKEGSKSRAKVSEQGLD 60
Query: 67 VYTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPPEYV 126
V T K AD++ +L PD Q +++ IEP L +G AL F HG NIH+ I PP V
Sbjct: 61 VDTPAAVAKWADVIMLLAPDTAQADIFKNDIEPNLSDGDALFFGHGLNIHFGLIKPPAEV 120
Query: 127 DVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAGVIETT 186
V MVAPK PG VR ++++G GVP L+AV QD TG + LAL+ AKAIG TRAGVI+TT
Sbjct: 121 TVAMVAPKGPGHLVRRQFVDGKGVPCLIAVDQDPTGKGEALALSYAKAIGGTRAGVIKTT 180
Query: 187 FKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMDLIYERG 246
FKDETE+DL GEQ VL GG EL+K GF+V+VE GYPPE+AYFE +E KLI+DL+YE G
Sbjct: 181 FKDETETDLFGEQAVLCGGTEELVKAGFDVMVESGYPPEMAYFEVLHELKLIVDLMYEGG 240
Query: 247 FTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADKASEVLE 306
M +VSDTA++GG GP+VID K+ M++ +++G+F K+ ++ + ++ LE
Sbjct: 241 IARMNYSVSDTAEFGGYLSGPRVIDAGTKDRMREILRDIQNGDFVKKLVANVEGGNKQLE 300
Query: 307 ELMKPIEEHEIEKVGRFIRK-MSGLER 332
+L K EH IE VG+ +R MS ++R
Sbjct: 301 QLRKENVEHPIEVVGKRLRDLMSWVDR 327
>sp|O53248|ILVC_MYCTU KETOL-ACID REDUCTOISOMERASE (ACETOHYDROXY-ACID ISOMEROREDUCTASE)
(ALPHA-KETO-BETA-HYDROXYLACIL REDUCTOISOMERASE)
>gi|7431343|pir||D70855 probable ilvC protein -
Mycobacterium tuberculosis (strain H37RV)
>gi|2791598|emb|CAA16086.1| (AL021287) ilvC
[Mycobacterium tuberculosis]
Length = 333
Score = 313 bits (793), Expect = 2e-84
Identities = 162/327 (49%), Positives = 217/327 (65%), Gaps = 1/327 (0%)
Query: 7 VYYDDEVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRAEKDGFE 66
++YDD+ + I++ + V VIGYG+QG A + ++RDSGV V +GL+ S + E+ G +
Sbjct: 1 MFYDDDADLSIIQGRKVGVIGYGSQGHAHSLSLRDSGVQVRVGLKQGSRSRPKVEEQGLD 60
Query: 67 VYTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPPEYV 126
V T E K AD+V +L PD Q +++ IEP L+ G AL F HG N+H+ I PP V
Sbjct: 61 VDTPAEVAKWADVVMVLAPDTAQAEIFAGDIEPNLKPGDALFFGHGLNVHFGLIKPPADV 120
Query: 127 DVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAGVIETT 186
V MVAPK PG VR ++++G GVP LVAV QD G+ LAL+ AKAIG TRAGVI+TT
Sbjct: 121 AVAMVAPKGPGHLVRRQFVDGKGVPCLVAVEQDPRGDGLALALSYAKAIGGTRAGVIKTT 180
Query: 187 FKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMDLIYERG 246
FKDETE+DL GEQ VL GG EL+K GFEV+VE GYP ELAYFE +E KLI+DL+YE G
Sbjct: 181 FKDETETDLFGEQTVLCGGTEELVKAGFEVMVEAGYPAELAYFEVLHELKLIVDLMYEGG 240
Query: 247 FTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADKASEVLE 306
M +VSDTA++GG GP+VID KE M+ ++ G F + ++ + ++ LE
Sbjct: 241 LARMYYSVSDTAEFGGYLSGPRVIDAGTKERMRDILREIQDGSFVHKLVADVEGGNKQLE 300
Query: 307 ELMKPIEEHEIEKVGRFIRK-MSGLER 332
EL + EH IE VG+ +R MS ++R
Sbjct: 301 ELRRQNAEHPIEVVGKKLRDLMSWVDR 327
>gb|AAD29665.1|AF124757_25 (AF124757) acetohydroxy acid isomeroreductase [Zymomonas mobilis]
Length = 339
Score = 312 bits (790), Expect = 5e-84
Identities = 158/324 (48%), Positives = 215/324 (65%), Gaps = 1/324 (0%)
Query: 5 VKVYYDDEVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGV-HVILGLRPSGSSWKRAEKD 63
+KVYYD + + ++K K +A++GYG+QG A A+N+RDSGV V + LRP +S K+A+
Sbjct: 1 MKVYYDSDADLGLIKSKKIAILGYGSQGHAHAQNLRDSGVAEVAIALRPDSASVKKAQDA 60
Query: 64 GFEVYTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPP 123
GF+V T EA K ADI+ IL PD Q +Y E ++ LR G A+ F+HG NIH+ I P
Sbjct: 61 GFKVLTNAEAAKWADILMILAPDEHQAAIYAEDLKDNLRPGSAIAFAHGLNIHFGLIEPR 120
Query: 124 EYVDVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAGVI 183
+ +DV M+APK PG VR +Y+ G GVP LVAV QD +GNA D+ALA A IG R+GVI
Sbjct: 121 KDIDVFMIAPKGPGHTVRSEYVRGGGVPCLVAVDQDASGNAHDIALAYASGIGGGRSGVI 180
Query: 184 ETTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMDLIY 243
ETTF++E E+DL GEQ VL GGL LI GFE L E GY PE+A+FE +E KLI+DLIY
Sbjct: 181 ETTFREEVETDLFGEQAVLCGGLTALITAGFETLTEAGYAPEMAFFECMHEMKLIVDLIY 240
Query: 244 ERGFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADKASE 303
E G M ++S+TA+YG + GP+VI++ K+ MK + ++SG F +++
Sbjct: 241 EAGIANMRYSISNTAEYGDIVSGPRVINEESKKAMKAILDDIQSGRFVSKFVLDNRAGQP 300
Query: 304 VLEELMKPIEEHEIEKVGRFIRKM 327
L+ K + H IE+VG +RKM
Sbjct: 301 ELKAARKRMAAHPIEQVGARLRKM 324
>sp|O33114|ILVC_MYCLE KETOL-ACID REDUCTOISOMERASE (ACETOHYDROXY-ACID ISOMEROREDUCTASE)
(ALPHA-KETO-BETA-HYDROXYLACIL REDUCTOISOMERASE)
>gi|11251570|pir||T45415 ketol-acid reductoisomerase
[imported] - Mycobacterium leprae
>gi|2414548|emb|CAB16437.1| (Z99263) ketol-acid
reductoisomerase [Mycobacterium leprae]
Length = 343
Score = 309 bits (784), Expect = 2e-83
Identities = 160/329 (48%), Positives = 217/329 (65%), Gaps = 1/329 (0%)
Query: 5 VKVYYDDEVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRAEKDG 64
+ ++YDD + I++ + V VIGYG+QG A + ++RDSGV V +GL S +A + G
Sbjct: 9 LSLFYDDNADLSIIQRRKVGVIGYGSQGYAHSLSLRDSGVQVRVGLPEGSKSRPKAFEQG 68
Query: 65 FEVYTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPPE 124
+V T E K AD++ +L+PD Q V+ IEP L+ G AL F HG NIH++ + P
Sbjct: 69 LDVDTPAEVAKWADVIMLLVPDTAQADVFENDIEPNLQPGDALFFGHGLNIHFELVKPSG 128
Query: 125 YVDVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAGVIE 184
V V MVAPK PG VR ++++G GVP L+AV QD TG + LAL+ AKAIG TRAGVI+
Sbjct: 129 DVTVAMVAPKGPGYLVRRQFVDGKGVPCLIAVNQDPTGTGEALALSYAKAIGGTRAGVIK 188
Query: 185 TTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMDLIYE 244
TTFKDETE+DL GEQ VL GG EL+K GF+V+VE GYPPE+AYFE +E KLI+DL+YE
Sbjct: 189 TTFKDETETDLFGEQAVLCGGTEELVKAGFDVMVEAGYPPEMAYFEVLHELKLIVDLMYE 248
Query: 245 RGFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADKASEV 304
G M +VSDTA++GG GP+VID KE M+ ++ G F K+ ++ + ++
Sbjct: 249 GGIARMNYSVSDTAEFGGYLSGPRVIDADTKERMRGILRDIQDGSFVKKLVANVEGGNKQ 308
Query: 305 LEELMKPIEEHEIEKVGRFIRK-MSGLER 332
LE L K EH IE G+ +R MS ++R
Sbjct: 309 LEVLRKENAEHPIEVTGKKLRDLMSWVDR 337
>emb|CAC01643.1| (AL391072) ketol-acid reductoisomerase [Streptomyces coelicolor
A3(2)]
Length = 332
Score = 309 bits (782), Expect = 4e-83
Identities = 156/324 (48%), Positives = 209/324 (64%)
Query: 4 VVKVYYDDEVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRAEKD 63
+ +++YD + + I++ + VAVIGYG+QG A A ++RDSGV V +GL S +AE+
Sbjct: 1 MAELFYDADADLSIIQGRKVAVIGYGSQGHAHALSLRDSGVDVRVGLHEGSKSKAKAEEQ 60
Query: 64 GFEVYTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPP 123
G V + EA AD++ IL+PD +Q +VY + I+ L++G AL F HG NI Y + PP
Sbjct: 61 GLRVVPVAEAAAEADVIMILVPDPIQAEVYEKDIKDNLKDGDALFFGHGLNIRYGFVKPP 120
Query: 124 EYVDVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAGVI 183
VDV MVAPK PG VR +Y EG GVP LVAV QD TGNA LAL+ AK IG TRAGVI
Sbjct: 121 AGVDVCMVAPKGPGHLVRRQYEEGRGVPCLVAVEQDATGNAFALALSYAKGIGGTRAGVI 180
Query: 184 ETTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMDLIY 243
TTF +ETE+DL GEQ VL GG+ L+K GFE L E GY PE+AYFE +E KLI+DL+Y
Sbjct: 181 RTTFTEETETDLFGEQAVLAGGVTALVKAGFETLTEAGYQPEIAYFECLHELKLIVDLMY 240
Query: 244 ERGFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADKASE 303
E G M ++S+TA++G GP++I D K M+K ++ G FAK W+ + +
Sbjct: 241 EGGLEKMRWSISETAEWGDYVTGPRIITDVTKAEMRKVLAEIQDGTFAKNWMDEYHGGLK 300
Query: 304 VLEELMKPIEEHEIEKVGRFIRKM 327
E K EH +E G+ +RK+
Sbjct: 301 KYNEYKKQDSEHLLETTGKELRKL 324
>sp|Q9Z565|ILVC_STRCO KETOL-ACID REDUCTOISOMERASE (ACETOHYDROXY-ACID ISOMEROREDUCTASE)
(ALPHA-KETO-BETA-HYDROXYLACIL REDUCTOISOMERASE)
>gi|7479125|pir||T35830 acetolactate synthase small
subunit - Streptomyces coelicolor
>gi|4467265|emb|CAB37590.1| (AL035569) acetolactate
synthase small subunit [Streptomyces coelicolor A3(2)]
Length = 332
Score = 307 bits (779), Expect = 9e-83
Identities = 156/324 (48%), Positives = 208/324 (64%)
Query: 4 VVKVYYDDEVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRAEKD 63
+ +++YD + + I++ + VAVIGYG+QG A A ++RDSGV V +GL S +AE+
Sbjct: 1 MAELFYDADADLSIIQGRKVAVIGYGSQGHAHALSLRDSGVDVRVGLHEGSKSKAKAEEQ 60
Query: 64 GFEVYTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPP 123
G V + EA AD++ IL+PD +Q +VY + I+ L++G AL F HG NI Y I PP
Sbjct: 61 GLRVVPVAEAAAEADVIMILVPDPIQAEVYEKDIKDNLKDGDALFFGHGLNIRYGFIKPP 120
Query: 124 EYVDVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAGVI 183
VDV MVAPK PG VR +Y EG GVP + AV QD TGNA LAL+ AK IG TRAGVI
Sbjct: 121 AGVDVCMVAPKGPGHLVRRQYEEGRGVPCIAAVEQDATGNAFALALSYAKGIGGTRAGVI 180
Query: 184 ETTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMDLIY 243
+TTF +ETE+DL GEQ VL GG L+K GFE L E GY PE+AYFE +E KLI+DL+Y
Sbjct: 181 KTTFTEETETDLFGEQAVLCGGTAALVKAGFETLTEAGYQPEIAYFECLHELKLIVDLMY 240
Query: 244 ERGFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADKASE 303
E G M ++S+TA++G GP++I D K MKK ++ G FAK W+ + +
Sbjct: 241 EGGLEKMRWSISETAEWGDYVTGPRIITDATKAEMKKVLAEIQDGTFAKNWMDEYHGGLK 300
Query: 304 VLEELMKPIEEHEIEKVGRFIRKM 327
E K EH +E G+ +RK+
Sbjct: 301 KYNEYKKQDSEHLLETTGKELRKL 324
>gb|AAG10503.1|AF279106_65 (AF279106) predicted ketol-acid reductoisomerase [uncultured
proteobacterium EBAC31A08]
Length = 347
Score = 307 bits (778), Expect = 1e-82
Identities = 156/330 (47%), Positives = 220/330 (66%), Gaps = 9/330 (2%)
Query: 5 VKVYYDDEVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRAEKDG 64
+K+YYD++ +++I+K V++IGYG+QG A A N+ +SGV V +GLR SSW +AE+ G
Sbjct: 1 MKIYYDEDANIEIIKGMNVSIIGYGSQGNAHANNLHESGVSVTVGLREGSSSWAKAEEAG 60
Query: 65 FEVYTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPPE 124
+V T+ ++V +AD+V IL PD Q +Y I+P L+ L F+HGFNIH+++IVP
Sbjct: 61 LKVQTVADSVIQADLVMILAPDEFQKNIYETEIKPNLKTSAILAFAHGFNIHFEKIVPEA 120
Query: 125 YVDVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTG----NAKDLALAMAKAIGCTRA 180
VIM+APK PG VR Y G GVP+L+A+Y+D +AKD+AL+ AKA G TRA
Sbjct: 121 TNSVIMIAPKGPGHTVRSTYTNGGGVPSLIAIYEDALSDEDYSAKDVALSYAKANGGTRA 180
Query: 181 GVIETTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMD 240
GV+ET+FK+ETE+DL GEQ VL GGL LIK GFE LVE GY E+AYFE +E KLI D
Sbjct: 181 GVLETSFKEETETDLFGEQAVLCGGLTALIKAGFETLVEAGYSEEMAYFECLHETKLITD 240
Query: 241 LIYERGFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADK 300
LI E G M ++S+TA+YG GPKVI K+ MK E ++SG+FA ++++ +
Sbjct: 241 LIQEGGIANMHYSISNTAEYGDYVSGPKVITSDTKKAMKGILENIQSGKFADDFLNDCRQ 300
Query: 301 ASE-----VLEELMKPIEEHEIEKVGRFIR 325
+++ V++ + + H IE VG +R
Sbjct: 301 SNDGTGGPVMKSNREATKIHPIESVGAELR 330
>pir||E82634 ketol-acid reductoisomerase XF1822 [imported] - Xylella fastidiosa
(strain 9a5c) >gi|9106901|gb|AAF84628.1|AE004003_7
(AE004003) ketol-acid reductoisomerase [Xylella
fastidiosa]
Length = 366
Score = 302 bits (766), Expect = 3e-81
Identities = 147/303 (48%), Positives = 204/303 (66%)
Query: 23 VAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRAEKDGFEVYTIEEAVKRADIVHI 82
+A+IGYG+QG A A N+RDSG +I+GLRP G + +A+ DGF V + ++A K AD+V +
Sbjct: 41 IAIIGYGSQGRAHALNLRDSGFDIIIGLRPGGPTEAKAQADGFTVQSPDQAAKHADLVAV 100
Query: 83 LIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPPEYVDVIMVAPKSPGKRVRE 142
L PD+VQ K+Y E + P +++G L F+HG N+HY I P +DV++VAPK PG VR
Sbjct: 101 LTPDMVQKKLYEEVLAPNIKQGACLLFAHGLNVHYGMITPRSDLDVVLVAPKGPGALVRR 160
Query: 143 KYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAGVIETTFKDETESDLIGEQLVL 202
+Y G GVP + AV+QD + +A+ LAL A +G RA +I+TTFK+ETE+DL GEQ VL
Sbjct: 161 EYEIGRGVPCIYAVHQDLSSHAEQLALTYAGGLGGARANIIKTTFKEETETDLFGEQAVL 220
Query: 203 VGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMDLIYERGFTGMLKAVSDTAKYGG 262
GG+ L++ GFE LVE GY PE+AY+E +E KLI+DL YE G T ML+ VS+TA+YG
Sbjct: 221 CGGVSSLVQAGFETLVEAGYQPEIAYYEVLHELKLIVDLFYEGGITRMLEFVSETAQYGD 280
Query: 263 LTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADKASEVLEELMKPIEEHEIEKVGR 322
GP+VID KE MK + ++ G F K WI++ ++ + EH IEKVG+
Sbjct: 281 YVSGPRVIDGSTKERMKAVLKDIQDGTFTKHWIAEYQAGLPNYKKYKQADLEHPIEKVGK 340
Query: 323 FIR 325
+R
Sbjct: 341 QLR 343
>sp|Q59818|ILVC_STRAW KETOL-ACID REDUCTOISOMERASE (ACETOHYDROXY-ACID ISOMEROREDUCTASE)
(ALPHA-KETO-BETA-HYDROXYLACIL REDUCTOISOMERASE)
>gi|642665|gb|AAA93100.1| (L39268) acetohydroxy acid
isomeroreductase [Streptomyces avermitilis]
Length = 333
Score = 299 bits (757), Expect = 3e-80
Identities = 153/324 (47%), Positives = 205/324 (63%)
Query: 4 VVKVYYDDEVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRAEKD 63
+ +++YD + + I++ + VAVIGYG+QG A A ++RDSGV V +GL S +AE+
Sbjct: 1 MAELFYDADADLSIIQGRKVAVIGYGSQGHAHALSLRDSGVDVRVGLHEGSKSKAKAEEQ 60
Query: 64 GFEVYTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPP 123
G V T EA AD++ IL+PD +Q +VY E I+ L++G AL F HG NI + I PP
Sbjct: 61 GLRVVTPSEAAAEADVIMILVPDPIQAQVYEESIKDNLKDGDALFFGHGLNIRFGFIKPP 120
Query: 124 EYVDVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAGVI 183
VDV MVAPK PG VR +Y EG GVP + AV QD TGN LAL+ AK IG TRAGVI
Sbjct: 121 AGVDVCMVAPKGPGHLVRRQYEEGRGVPCIAAVEQDATGNGFALALSYAKGIGGTRAGVI 180
Query: 184 ETTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMDLIY 243
+TTF +ETE+DL GEQ VL GG L+K GFE L E GY PE+AYFE +E KLI+DL+Y
Sbjct: 181 KTTFTEETETDLFGEQAVLCGGTAALVKAGFESLTEAGYQPEIAYFECLHELKLIVDLMY 240
Query: 244 ERGFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADKASE 303
E G M ++S+TA++G GP++I D K MKK ++ G FA+ W+ + +
Sbjct: 241 EGGLEKMRWSISETAEWGDYVTGPRIITDATKAEMKKVLAEIQDGTFAQAWMDEYHGGLK 300
Query: 304 VLEELMKPIEEHEIEKVGRFIRKM 327
E E H +E G+ +R +
Sbjct: 301 KYNEYKTQDENHLLETTGKELRNV 324
>sp|O32414|ILVC_RHOMO KETOL-ACID REDUCTOISOMERASE (ACETOHYDROXY-ACID ISOMEROREDUCTASE)
(ALPHA-KETO-BETA-HYDROXYLACIL REDUCTOISOMERASE)
>gi|2529237|dbj|BAA22800.1| (D50654) acetohydroxy acid
isomeroreductase [Phaeospirillum molischianum]
Length = 339
Score = 298 bits (756), Expect = 5e-80
Identities = 156/324 (48%), Positives = 212/324 (65%), Gaps = 1/324 (0%)
Query: 5 VKVYYDDEVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVH-VILGLRPSGSSWKRAEKD 63
++VYYD + ++++K K VAVIGYG+QG A N+RDSGV V + LRP +S K+AE +
Sbjct: 1 MRVYYDRDADVNLIKSKKVAVIGYGSQGHAHVLNLRDSGVKDVAVALRPGSASIKKAEAE 60
Query: 64 GFEVYTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPP 123
G +V T EA AD+V IL PD +Q +Y+ + L+ G AL F+HG IH+K I
Sbjct: 61 GLKVLTPAEAAAWADVVMILTPDELQADLYKSELAANLKPGAALVFAHGLAIHFKLIEAR 120
Query: 124 EYVDVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAGVI 183
+DV MVAPK PG VR +YL+G GVP LVAV Q+ TGNA +LAL+ A AIG R+G+I
Sbjct: 121 ADLDVFMVAPKGPGHTVRGEYLKGGGVPCLVAVAQNPTGNALELALSYASAIGGGRSGII 180
Query: 184 ETTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMDLIY 243
ETTF++E E+DL GEQ+VL GGL +LI+ GFE LVE GY PE+AYFE +E KLI+DLIY
Sbjct: 181 ETTFREECETDLFGEQVVLCGGLSKLIQYGFETLVEAGYAPEMAYFECLHEVKLIVDLIY 240
Query: 244 ERGFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADKASE 303
E G M ++S+TA+YG G ++I + K MK+ ++SG F ++W+ +
Sbjct: 241 EGGIANMRYSISNTAEYGDYVTGSRIITEATKAEMKRVLADIQSGRFVRDWMLECKAGQP 300
Query: 304 VLEELMKPIEEHEIEKVGRFIRKM 327
+ + EH IE VG +R M
Sbjct: 301 SFKATRRIQXEHVIEVVGEKLRGM 324
>sp|Q57179|ILVC_CORGL KETOL-ACID REDUCTOISOMERASE (ACETOHYDROXY-ACID ISOMEROREDUCTASE)
(ALPHA-KETO-BETA-HYDROXYLACIL REDUCTOISOMERASE)
>gi|538964|pir||C48648 ketol-acid reductoisomerase (EC
1.1.1.86) - Corynebacterium glutamicum
>gi|400336|gb|AAA62431.1| (L09232) acetohydroxy acid
isomeroreductase [Corynebacterium glutamicum]
>gi|538223|dbj|BAA03414.1| (D14551) acetohydroxy acid
isomeroreductase [Brevibacterium flavum]
>gi|1097110|prf||2113260A acetohydroxy acid
isomeroreductase [Brevibacterium flavum]
Length = 338
Score = 297 bits (752), Expect = 1e-79
Identities = 150/323 (46%), Positives = 208/323 (63%)
Query: 5 VKVYYDDEVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRAEKDG 64
+++ YD + + +++ + VA++GYG+QG A ++N+RDSGV V++GLR S ++A++ G
Sbjct: 3 IELLYDADADLSLIQGRKVAIVGYGSQGHAHSQNLRDSGVEVVIGLREGSKSAEKAKEAG 62
Query: 65 FEVYTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPPE 124
FEV T EA AD++ +L PD Q +++ IEP L G AL F HG NIH+ I P +
Sbjct: 63 FEVKTTAEAAAWADVIMLLAPDTSQAEIFTNDIEPNLNAGDALLFGHGLNIHFDLIKPAD 122
Query: 125 YVDVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAGVIE 184
+ V MVAPK PG VR ++++G GVP L+AV QD TG A+ L L+ A AIG RAGVI
Sbjct: 123 DIIVGMVAPKGPGHLVRRQFVDGKGVPCLIAVDQDPTGTAQALTLSYAAAIGGARAGVIP 182
Query: 185 TTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMDLIYE 244
TTF+ ET +DL GEQ VL GG EL+K GFEVL E GY PE+AYFE +E KLI+DL++E
Sbjct: 183 TTFEAETVTDLFGEQAVLCGGTEELVKVGFEVLTEAGYEPEMAYFEVLHELKLIVDLMFE 242
Query: 245 RGFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADKASEV 304
G + M +VSDTA++GG GP+VID K MK ++ G F K I+ + +
Sbjct: 243 GGISNMNYSVSDTAEFGGYLSGPRVIDADTKSRMKDILTDIQDGTFTKRLIANVENGNTE 302
Query: 305 LEELMKPIEEHEIEKVGRFIRKM 327
LE L H IE+ G +R +
Sbjct: 303 LEGLRASYNNHPIEETGAKLRDL 325
>sp|P97115|ILVC_LEUMC KETOL-ACID REDUCTOISOMERASE (ACETOHYDROXY-ACID ISOMEROREDUCTASE)
(ALPHA-KETO-BETA-HYDROXYLACIL REDUCTOISOMERASE)
>gi|1857048|gb|AAB48550.1| (U50749) acetohydroxyacid
isomeroreductase [Leuconostoc mesenteroides subsp.
cremoris]
Length = 347
Score = 293 bits (743), Expect = 2e-78
Identities = 146/322 (45%), Positives = 214/322 (66%), Gaps = 1/322 (0%)
Query: 6 KVYYDDEVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRAEKDGF 65
K++YD ++ L++K +AVIGYG QG AQA N+R SG VI+GLRP G S+ +KDGF
Sbjct: 4 KMFYDKDIDTKPLENKKIAVIGYGAQGHAQANNLRVSGFDVIMGLRP-GKSFDSVKKDGF 62
Query: 66 EVYTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPPEY 125
EVY+ EA +AD+V + PD +Q V+ + +EP L+ G LGFSHGFNI Y I P
Sbjct: 63 EVYSAAEATAQADVVMMETPDELQAAVWEKEVEPNLKAGSDLGFSHGFNIVYGLIKPNAD 122
Query: 126 VDVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAGVIET 185
++V+++APK PG R +++EG G+P+L V+QD TG+ ++A A AK IG AG++ET
Sbjct: 123 INVMIIAPKGPGNIERRQFVEGGGIPSLYGVHQDPTGDTAEVAKAYAKGIGSGCAGILET 182
Query: 186 TFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMDLIYER 245
TF++ET DL GEQ VL GGL +LI+ GF LVE GY PELAYFE +E K+I+DLI+E
Sbjct: 183 TFEEETTEDLFGEQAVLCGGLTQLIEAGFNTLVEAGYSPELAYFETSHEMKMIVDLIFEG 242
Query: 246 GFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADKASEVL 305
GF M S+T +YG + GP++I + K+ M+ + ++ G +AK+W+++ + + L
Sbjct: 243 GFEKMRHDCSNTCEYGEMLNGPRIITEESKQGMRDVLKDIQDGTYAKKWLAEYNSGLKDL 302
Query: 306 EELMKPIEEHEIEKVGRFIRKM 327
E++ + E+ G+ +R M
Sbjct: 303 EKMRTEYKSGLYEQTGKKVRAM 324
>pir||A71945 ketol-acid reductoisomerase - Helicobacter pylori (strain J99)
>gi|4154860|gb|AAD05913.1| (AE001468) KETOL-ACID
REDUCTOISOMERASE [Helicobacter pylori J99]
Length = 330
Score = 275 bits (697), Expect = 4e-73
Identities = 134/320 (41%), Positives = 220/320 (67%), Gaps = 2/320 (0%)
Query: 7 VYYDDEVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRAEKDGFE 66
VYYD ++ + +++ V +IGYG QGEAQA N+RDS V V +GL S +A+K+GFE
Sbjct: 5 VYYDKDIDLGVIQSLQVGIIGYGVQGEAQALNLRDSKVKVRIGLYQGSLSVSKAKKEGFE 64
Query: 67 VYTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPPEYV 126
V ++E V+++D++ L+PD + +V + + P+L+EGQ +GF+HGF++H+ Q+V P+ V
Sbjct: 65 VLGVKELVQQSDVIMALLPDELHKEVLEKEVIPFLKEGQIIGFAHGFSVHFNQVVLPKGV 124
Query: 127 DVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYT-GNAKDLALAMAKAIGCTRAGVIET 185
I+VAPK PG +RE+YL+ G+ L+A+ Q+ + NAK +AL+ AKA+G R GV+ET
Sbjct: 125 GAILVAPKGPGSALREEYLKNRGLYHLIAIEQESSIHNAKAVALSYAKAMGGGRMGVLET 184
Query: 186 TFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMDLIYER 245
+FK+E ESDL GEQ VL GGL +++ GFE L++ GYP ELAYFE +E KL+ DL++ +
Sbjct: 185 SFKEECESDLFGEQAVLCGGLEAIVRMGFETLIKAGYPEELAYFECVHEVKLVADLLHYK 244
Query: 246 GFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADKASEVL 305
G G+ K +S+TA++G + + + + +++ M+K +++++G FAK+++ + L
Sbjct: 245 GVEGLRKHISNTAEFGAIK-AREPMGNLLEKRMQKILKKIQNGAFAKDFLLEKSLNYPRL 303
Query: 306 EELMKPIEEHEIEKVGRFIR 325
K ++E +IE++G +R
Sbjct: 304 NTERKALKETKIEQIGEILR 323
>sp|O25097|ILVC_HELPY KETOL-ACID REDUCTOISOMERASE (ACETOHYDROXY-ACID ISOMEROREDUCTASE)
(ALPHA-KETO-BETA-HYDROXYLACIL REDUCTOISOMERASE)
>gi|7427680|pir||B64561 ketol-acid reductoisomerase (EC
1.1.1.86) - Helicobacter pylori (strain 26695)
>gi|2313431|gb|AAD07399.1| (AE000551) ketol-acid
reductoisomerase (ilvC) [Helicobacter pylori 26695]
Length = 330
Score = 275 bits (696), Expect = 5e-73
Identities = 134/320 (41%), Positives = 217/320 (66%), Gaps = 2/320 (0%)
Query: 7 VYYDDEVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRAEKDGFE 66
VYYD ++ + +++ V +IGYG QGEAQA N+RDS V +GL S +A+K+GFE
Sbjct: 5 VYYDKDIDLGVIQSLQVGIIGYGAQGEAQALNLRDSKVKARIGLYQGSLSVSKAKKEGFE 64
Query: 67 VYTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPPEYV 126
V ++E V+ +D++ L+PD + +V + + P+L+EGQ +GF+HGF++H+ Q+V P+ V
Sbjct: 65 VLEVKELVQNSDVIMALLPDELHKEVLEKEVIPFLKEGQIVGFAHGFSVHFNQVVLPKGV 124
Query: 127 DVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYT-GNAKDLALAMAKAIGCTRAGVIET 185
I+VAPK PG +RE+YL+ G+ L+A+ Q+ + NAK +AL+ AKA+G R GV+ET
Sbjct: 125 GAILVAPKGPGSALREEYLKNRGLYHLIAIEQESSIHNAKAVALSYAKAMGGGRMGVLET 184
Query: 186 TFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMDLIYER 245
+FK+E ESDL GEQ VL GGL +++ GFE L++ GYP ELAYFE +E KL+ DL++ +
Sbjct: 185 SFKEECESDLFGEQAVLCGGLEAIVRMGFETLIKAGYPEELAYFECVHEVKLVADLLHYK 244
Query: 246 GFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADKASEVL 305
G G+ K +S+TA++G + + + +K+ M+K +++++G FAK+++ + L
Sbjct: 245 GVEGLRKHISNTAEFGAIK-AREPMGKLLKKRMQKILKKIQNGSFAKDFLLEKSLNYPRL 303
Query: 306 EELMKPIEEHEIEKVGRFIR 325
K ++E +IE++G +R
Sbjct: 304 NTERKALKETKIEQIGEILR 323
>sp|Q52955|ILVC_RHIME KETOL-ACID REDUCTOISOMERASE (ACETOHYDROXY-ACID ISOMEROREDUCTASE)
(ALPHA-KETO-BETA-HYDROXYLACIL REDUCTOISOMERASE)
>gi|152246|gb|AAA26293.1| (M74076) acetohydroxy acid
isomeroreductase [Sinorhizobium meliloti]
Length = 337
Score = 240 bits (606), Expect = 2e-62
Identities = 131/327 (40%), Positives = 199/327 (60%), Gaps = 9/327 (2%)
Query: 5 VKVYYDDEVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGV-HVILGLRPSGSSWKRAEKD 63
++VYYD + ++++K K VA+IGYG+Q A A N++DSG +V + L+ ++ K+AE D
Sbjct: 1 MRVYYDRDADLNLIKSKKVAIIGYGSQA-AHALNLKDSGAQNVAIALKSGSATAKKAEAD 59
Query: 64 GFEVYTIEEAVKRADIVHILIPDLVQPKVYRE---HIEPYLREGQALGFSHGFNIHYKQI 120
GF+V T+ EA AD++ + P +P R R+ S + +
Sbjct: 60 GFKVMTVAEAAAWADLMMMATPTSCRPTSTRPTSPETSATARQSPLRTASTSTSASSSRR 119
Query: 121 VPPEYVDVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRA 180
+ D + PG VR +Y +G GVP LVAV+QD +GNA DLAL+ A +G R+
Sbjct: 120 LGRRRND----RSEGPGHTVRGEYQKGGGVPCLVAVHQDASGNALDLALSYACGVGGGRS 175
Query: 181 GVIETTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMD 240
G+IET FK+E E+DL GEQ+VL GGL+ELI+ GFE LVE GY PE+AYFE +E KLI+D
Sbjct: 176 GIIETNFKEECETDLFGEQVVLCGGLVELIRAGFETLVEAGYAPEMAYFECLHEVKLIVD 235
Query: 241 LIYERGFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADK 300
LIYE G M ++S+TA++G GP++I + K MK+ + +++G+F EW+ +
Sbjct: 236 LIYEGGIANMNYSISNTAEWGEYVTGPRIITEDTKAEMKRVLKDIQTGKFTSEWMQEYRS 295
Query: 301 ASEVLEELMKPIEEHEIEKVGRFIRKM 327
+ + + + + H+IE+VG +R M
Sbjct: 296 GAARFKGIRRVNDSHQIEEVGAKLRAM 322
>pir||T40532 ketol-acid reductoisomerase precursor - fission yeast
(Schizosaccharomyces pombe) >gi|3116142|emb|CAA18891.1|
(AL023288) ketol-acid reductoisomerase precursor
[Schizosaccharomyces pombe]
Length = 404
Score = 199 bits (501), Expect = 4e-50
Identities = 120/326 (36%), Positives = 194/326 (58%), Gaps = 14/326 (4%)
Query: 12 EVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRAEKDGF----EV 67
E +D K+ T+A+IGYG+QG Q N RD G++VI+G+R G+SWK+A +DG+ +
Sbjct: 76 EKLVDYFKNDTLAIIGYGSQGHGQGLNARDQGLNVIVGVRKDGASWKQAIEDGWVPGKTL 135
Query: 68 YTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYK---QIVPPE 124
+ +EEA+K+ I+ L+ D Q + + + I P + +G+ L FSHGF++ +K +I PP+
Sbjct: 136 FPVEEAIKKGSIIMNLLSDAAQTETWPK-IAPLITKGKTLYFSHGFSVIFKDQTKIHPPK 194
Query: 125 YVDVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAGVIE 184
VDVI+VAPK G+ VR + EG G+ + AVYQD TG A++ A+ +A A+G + +
Sbjct: 195 DVDVILVAPKGSGRTVRTLFKEGRGINSSFAVYQDVTGKAQEKAIGLAVAVG--SGFIYQ 252
Query: 185 TTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEA-KLIMDLIY 243
TTFK E SDL+GE+ L+GG+ L ++VL E G+ P A+ E EA + + LI
Sbjct: 253 TTFKKEVISDLVGERGCLMGGINGLFLAQYQVLRERGHSPAEAFNETVEEATQSLYPLIG 312
Query: 244 ERGFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWI--SKADKA 301
+ G M A S TA+ G + P+ ++ + K+ + + + V +G AK + + A
Sbjct: 313 KYGLDYMFAACSTTARRGAIDWTPRFLEAN-KKVLNELYDNVENGNEAKRSLEYNSAPNY 371
Query: 302 SEVLEELMKPIEEHEIEKVGRFIRKM 327
E+ ++ ++ I EI K G +R +
Sbjct: 372 RELYDKELEEIRNLEIWKAGEVVRSL 397
>sp|P78827|ILV5_SCHPO PROBABLE KETOL-ACID REDUCTOISOMERASE, MITOCHONDRIAL PRECURSOR
(ACETOHYDROXY-ACID REDUCTOISOMERASE)
(ALPHA-KETO-BETA-HYDROXYLACIL REDUCTOISOMERASE)
>gi|11251583|pir||T42540 probable ketol-acid
reductoisomerase (EC 1.1.1.86) - fission yeast
(Schizosaccharomyces pombe) >gi|1749558|dbj|BAA13837.1|
(D89175) similar to Saccharomyces cerevisiae ketol-acid
reductoisomerase precursor, SWISS-PROT Accession Number
P38674 [Schizosaccharomyces pombe]
Length = 404
Score = 191 bits (480), Expect = 1e-47
Identities = 118/326 (36%), Positives = 191/326 (58%), Gaps = 14/326 (4%)
Query: 12 EVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRAEKDGF----EV 67
E +D K+ T+A+IG G+QG Q N RD G++VI+G+R G+SWK+A +DG+ +
Sbjct: 76 EKLVDYFKNDTLAIIGSGSQGHGQGLNARDQGLNVIVGVRKDGASWKQAIEDGWVPGKTL 135
Query: 68 YTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYK---QIVPPE 124
+ +EEA+K+ I+ L+ D Q + + + I P + +G+ L FSHGF++ +K +I PP+
Sbjct: 136 FPVEEAIKKGSIIMNLLSDAAQTETWPK-IAPLITKGKTLYFSHGFSVIFKDQTKIHPPK 194
Query: 125 YVDVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAGVIE 184
VDVI+VAPK G+ VR + EG G+ + AVYQD TG A++ + +A A+G + +
Sbjct: 195 DVDVILVAPKGSGRTVRTLFKEGRGINSSFAVYQDVTGKAQEKTIGLAVAVG--SGFIYQ 252
Query: 185 TTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEA-KLIMDLIY 243
TTFK E SDL+GE+ L+GG+ L ++VL E G+ P A+ E EA + + LI
Sbjct: 253 TTFKKEVISDLVGERGCLMGGIPGLFLAQYQVLRERGHSPAEAFPETVEEATQSLYPLIG 312
Query: 244 ERGFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWI--SKADKA 301
+ G M A S TA+ G + P+ ++ + K+ + + + V +G AK + + A
Sbjct: 313 KYGLDYMFAACSTTARRGAIDWTPRFLEAN-KKVLNELYDNVENGNEAKRSLEYNSAPNY 371
Query: 302 SEVLEELMKPIEEHEIEKVGRFIRKM 327
E+ ++ ++ I EI K G R +
Sbjct: 372 RELYDKELEEIRNLEIWKAGEVGRSL 397
>gi|6323387 acetohydroxyacid reductoisomerase; Ilv5p [Saccharomyces cerevisiae]
>gi|124371|sp|P06168|ILV5_YEAST KETOL-ACID
REDUCTOISOMERASE, MITOCHONDRIAL PRECURSOR
(ACETOHYDROXY-ACID REDUCTOISOMERASE)
(ALPHA-KETO-BETA-HYDROXYLACIL REDUCTOISOMERASE)
>gi|83292|pir||A24709 ketol-acid reductoisomerase (EC
1.1.1.86) ILV5 - yeast (Saccharomyces cerevisiae)
>gi|3827|emb|CAA28643.1| (X04969) acetohydroxyacid
reductoisomerase (AA 1-395) [Saccharomyces cerevisiae]
>gi|609403|gb|AAB67753.1| (U19102) Ilv5p:
acetohydroxyacid reductoisomerase [Saccharomyces
cerevisiae]
Length = 395
Score = 190 bits (477), Expect = 2e-47
Identities = 126/330 (38%), Positives = 186/330 (56%), Gaps = 22/330 (6%)
Query: 12 EVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRAEKDGF----EV 67
E +D K+ T A+IGYG+QG Q N+RD+G++VI+G+R G+SWK A +DG+ +
Sbjct: 69 EKLLDYFKNDTFALIGYGSQGYGQGLNLRDNGLNVIIGVRKDGASWKAAIEDGWVPGKNL 128
Query: 68 YTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIV---PPE 124
+T+E+A+KR V L+ D Q + + I+P L +G+ L FSHGF+ +K + PP+
Sbjct: 129 FTVEDAIKRGSYVMNLLSDAAQSETW-PAIKPLLTKGKTLYFSHGFSPVFKDLTHVEPPK 187
Query: 125 YVDVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAGVIE 184
+DVI+VAPK G+ VR + EG G+ + AV+ D TG A + A A+A AIG V +
Sbjct: 188 DLDVILVAPKGSGRTVRSLFKEGRGINSSYAVWNDVTGKAHEKAQALAVAIG--SGYVYQ 245
Query: 185 TTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEA-KLIMDLIY 243
TTF+ E SDL GE+ L+GG+ + ++VL E G+ P A+ E EA + + LI
Sbjct: 246 TTFEREVNSDLYGERGCLMGGIHGMFLAQYDVLRENGHSPSEAFNETVEEATQSLYPLIG 305
Query: 244 ERGFTGMLKAVSDTAKYGGLTVGP------KVIDDHVKENMKKFAERVRSGEFAKEWISK 297
+ G M A S TA+ G L P K + + E+ K E RS EF +
Sbjct: 306 KYGMDYMYDACSTTARRGALDWYPIFKNALKPVFQDLYESTKNGTETKRSLEF-----NS 360
Query: 298 ADKASEVLEELMKPIEEHEIEKVGRFIRKM 327
E LE+ + I EI KVG+ +RK+
Sbjct: 361 QPDYREKLEKELDTIRNMEIWKVGKEVRKL 390
>gb|AAB33579.1| (S77496) acetohydroxy-acid isomeroreductase, Ilv5x [Saccharomyces
cerevisiae=brewing yeast, CC45, Peptide, 395 aa]
Length = 395
Score = 189 bits (474), Expect = 5e-47
Identities = 126/330 (38%), Positives = 186/330 (56%), Gaps = 22/330 (6%)
Query: 12 EVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRAEKDGF----EV 67
E +D K+ T A+IGYG+QG Q N+RD+G++VI+G+R G+SWK A +DG+ +
Sbjct: 69 EKLLDYFKNDTFALIGYGSQGYGQGLNLRDNGLNVIIGVRKDGASWKAAIEDGWVPGKNL 128
Query: 68 YTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIV---PPE 124
+T+E+A+KR V L+ D Q + + I+P L +G+ L FSHGF+ +K + PP+
Sbjct: 129 FTVEDAIKRGCYVMNLLSDAAQSETW-PAIKPLLTKGKTLYFSHGFSPVFKDLTHVEPPK 187
Query: 125 YVDVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAGVIE 184
+DVI+VAPK G+ VR + EG G+ + AV+ D TG A + A A+A AIG V +
Sbjct: 188 DLDVILVAPKGSGRTVRSLFKEGRGINSSYAVWNDVTGKAHEKAQALAVAIG--SGYVYQ 245
Query: 185 TTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEA-KLIMDLIY 243
TTF+ E SDL GE+ L+GG+ + ++VL E G+ P A+ E EA + + LI
Sbjct: 246 TTFEREVNSDLYGERGCLMGGIHGMFLAQYDVLRENGHSPSEAFNETVEEATQSLYPLIG 305
Query: 244 ERGFTGMLKAVSDTAKYGGLTVGP------KVIDDHVKENMKKFAERVRSGEFAKEWISK 297
+ G M A S TA+ G L P K + + E+ K E RS EF +
Sbjct: 306 KYGMDYMYDACSTTARRGALDWYPIFKNALKPVFQDLYESTKNGTETKRSLEF-----NS 360
Query: 298 ADKASEVLEELMKPIEEHEIEKVGRFIRKM 327
E LE+ + I EI KVG+ +RK+
Sbjct: 361 QPDYREKLEKELDTIRNMEIWKVGKEVRKL 390
>gb|AAB33578.1| (S77495) acetohydroxy-acid isomeroreductase, Ilv5g [Saccharomyces
cerevisiae=brewing yeast, CC45, Peptide, 395 aa]
Length = 395
Score = 187 bits (470), Expect = 2e-46
Identities = 124/330 (37%), Positives = 187/330 (56%), Gaps = 22/330 (6%)
Query: 12 EVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRAEKDGF----EV 67
E ++ KD T A+IGYG+QG Q N+RD+G++VI+G+R G+SWK A +DG+ +
Sbjct: 69 EKLLNYFKDDTFALIGYGSQGYGQGLNLRDNGLNVIIGVRKDGASWKAAIEDGWVPGQNL 128
Query: 68 YTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIV---PPE 124
+++E+A+K+ + V L+ D Q + + I+P L +G+ L FSHGF+ +K + PP+
Sbjct: 129 FSVEDAIKKGNYVMNLLSDAAQSETW-PTIKPLLTKGKTLYFSHGFSPVFKDLTHVEPPK 187
Query: 125 YVDVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAGVIE 184
+DVI+VAPK G+ VR + EG G+ + AV+ D TG A + A A+A AIG V +
Sbjct: 188 DLDVILVAPKGSGRTVRSLFKEGRGINSSYAVWNDVTGKAHEKAQALAVAIG--SGYVYQ 245
Query: 185 TTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEA-KLIMDLIY 243
TTF+ E SDL GE+ L+GG+ + ++VL E G+ P A+ E EA + + LI
Sbjct: 246 TTFEREVNSDLYGERGCLMGGIHGMFLAQYDVLRENGHSPSEAFNETVEEATQSLYPLIG 305
Query: 244 ERGFTGMLKAVSDTAKYGGLTVGP------KVIDDHVKENMKKFAERVRSGEFAKEWISK 297
+ G M A S TA+ G L P K + + E+ K E RS EF +
Sbjct: 306 KYGMDYMYDACSTTARRGALDWYPIFKNALKPVFQDLYESTKNGTETKRSLEF-----NS 360
Query: 298 ADKASEVLEELMKPIEEHEIEKVGRFIRKM 327
E LE+ + I EI KVG+ +RK+
Sbjct: 361 QPDYREKLEKELVTIRNMEIWKVGKEVRKL 390
>sp|P38674|ILV5_NEUCR KETOL-ACID REDUCTOISOMERASE PRECURSOR (ACETOHYDROXY-ACID
REDUCTOISOMERASE) (ALPHA-KETO-BETA-HYDROXYLACIL
REDUCTOISOMERASE) >gi|322996|pir||JC1428 ketol-acid
reductoisomerase (EC 1.1.1.86) - Neurospora crassa
>gi|168822|gb|AAB00797.1| (M84189)
alpha-keto-beta-hydroxylacyl reductoisomerase
[Neurospora crassa]
Length = 400
Score = 187 bits (469), Expect = 2e-46
Identities = 121/322 (37%), Positives = 183/322 (56%), Gaps = 16/322 (4%)
Query: 12 EVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRAEKDGF----EV 67
E +D K+ T+A+IGYG+QG Q N+RD+G++VI+G+R +G SW+ A +DG+ +
Sbjct: 75 EKLLDYFKNDTLALIGYGSQGHGQGLNLRDNGLNVIVGVRKNGKSWEDAIQDGWVPGKNL 134
Query: 68 YTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVP---PE 124
+ ++EA+ R IV L+ D Q + + HI+P + +G+ L FSHGF+ +K + P
Sbjct: 135 FDVDEAISRGTIVMNLLSDAAQSETW-PHIKPQITKGKTLYFSHGFSPVFKDLTKVEVPT 193
Query: 125 YVDVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAGVIE 184
VDVI+VAPK G+ VR + EG G+ + AVYQD TG AK+ A+A+ A+G + E
Sbjct: 194 DVDVILVAPKGSGRTVRSLFREGRGINSSFAVYQDVTGKAKEKAVALGVAVG--SGYLYE 251
Query: 185 TTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEA-KLIMDLIY 243
TTF+ E SDL GE+ L+GG+ + +EVL E G+ P A+ E EA + + LI
Sbjct: 252 TTFEKEVYSDLYGERGCLMGGIHGMFLAQYEVLRERGHSPSEAFNETVEEATQSLYPLIG 311
Query: 244 ERGFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAK---EWISKADK 300
G M A S TA+ G + PK D +K + V++G+ K E+ S+ D
Sbjct: 312 AHGMDWMFDACSTTARRGAIDWTPK-FKDALKPVFNNLYDSVKNGDERKRSLEYNSQPD- 369
Query: 301 ASEVLEELMKPIEEHEIEKVGR 322
E E + I EI + G+
Sbjct: 370 YRERYEAELDEIRNLEIWRAGK 391
>gb|AAK42136.1| Ketol-acid reductoisomerase (ilvC-3) [Sulfolobus solfataricus]
Length = 332
Score = 185 bits (465), Expect = 6e-46
Identities = 126/323 (39%), Positives = 181/323 (56%), Gaps = 11/323 (3%)
Query: 12 EVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRAEKDGFEVYTIE 71
+ S++ LK KT+AVIGYGNQG QA MR++G++VI+G + A K+GFEVY I
Sbjct: 7 DASLEPLKGKTIAVIGYGNQGRVQANIMRENGLNVIIG-NVKDRYYDLAIKEGFEVYDIG 65
Query: 72 EAVKRADIVHILIPDLVQPKVYREHIEPYLREGQ---ALGFSHGFNIHYKQIVPPEYVDV 128
EAVK+AD+ +LIPD + ++Y + I P L EG+ L F+ G+N+ + I PP+ VD
Sbjct: 66 EAVKKADVAFLLIPDEIMKEIYEKKIAPIL-EGKKEFVLDFASGYNVAFGLIRPPKNVDT 124
Query: 129 IMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAGV-IETTF 187
+MVAP+ G+ + + + +G G P L+ V QD +G A D A A+AK IG G+ + ++F
Sbjct: 125 VMVAPRMVGEGIMDLHKQGKGYPVLLGVKQDASGKAWDYAKAIAKGIGAIPGGIAVISSF 184
Query: 188 KDETESDLIGEQLVLVGGLIELIKKGFEVLV-ELGYPPELAYFE--ACNEAKLIMDLIYE 244
++E DL+ E V L IK F+V V E G PE A E A E I LI E
Sbjct: 185 EEEALLDLMSEH-TWVPILFGAIKACFDVAVKEYGVSPEAALLEFYASGELVEIARLIAE 243
Query: 245 RGFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADKASEV 304
G + S T++YG LT K D VKE +K A+ + G FAKEW + V
Sbjct: 244 EGIFNQMVHHSTTSQYGTLTRMFKYY-DLVKEIVKDEAKYIWDGSFAKEWTLEQQAGYPV 302
Query: 305 LEELMKPIEEHEIEKVGRFIRKM 327
L + + E+ K + + K+
Sbjct: 303 FYRLWELAVQSEMAKAEKELYKI 325
>gb|AAK41560.1| Ketol-acid reductoisomerase (ilvC-2) [Sulfolobus solfataricus]
Length = 333
Score = 183 bits (459), Expect = 3e-45
Identities = 121/324 (37%), Positives = 182/324 (55%), Gaps = 9/324 (2%)
Query: 12 EVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRAEKDGFEVYTIE 71
+ ++D LK KT+ VIGYGNQG QA MR++G++VI+G ++ A+K+GFEVY I+
Sbjct: 7 DANLDPLKGKTIGVIGYGNQGRVQATIMRENGLNVIVG-NVKDKYYELAKKEGFEVYEID 65
Query: 72 EAVKRADIVHILIPDLVQPKVYREHIEPYLREGQ--ALGFSHGFNIHYKQIVPPEYVDVI 129
EAV+R+D+ +LIPD V +VY + I P L+ + L F+ G+N+ + I PP+ VD I
Sbjct: 66 EAVRRSDVALLLIPDEVMKEVYEKKIAPVLQGKKEFVLDFASGYNVAFGLIRPPKSVDTI 125
Query: 130 MVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAGV-IETTFK 188
MVAP+ G+ + + + +G G P L+ V QD +G A D A A+AK IG G+ + ++F+
Sbjct: 126 MVAPRMVGEGIMDLHKQGKGYPVLLGVKQDASGKAWDYAKAIAKGIGAIPGGIAVISSFE 185
Query: 189 DETESDLIGEQLVLVGGLIELIKKGFEVLV-ELGYPPELAYFE--ACNEAKLIMDLIYER 245
+E DL+ E V L IK +++ V E G PE A E A E I LI E
Sbjct: 186 EEALLDLMSEH-TWVPILFGAIKACYDIAVKEYGVSPEAALLEFYASGELAEIARLIAEE 244
Query: 246 GFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADKASEVL 305
G + S T++YG LT K D V+ ++ A+ + G FAKEW + V
Sbjct: 245 GIFNQMVHHSTTSQYGTLTRMFKYY-DVVRRIVENEAKYIWDGSFAKEWSLEQQAGYPVF 303
Query: 306 EELMKPIEEHEIEKVGRFIRKMSG 329
L + + E+ K + + K+ G
Sbjct: 304 YRLWELATQSEMAKAEKELYKLLG 327
>emb|CAA76356.1| (Y16743) ketol-acid reductoisomerase [Piromyces sp. E2]
Length = 352
Score = 167 bits (419), Expect = 1e-40
Identities = 122/330 (36%), Positives = 177/330 (52%), Gaps = 18/330 (5%)
Query: 9 YDDEVSMDILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSGSSWKRAEKDGF--- 65
+ E +I KD VIGYG QG Q++N+RD G VI+GLR G SW A++DG+
Sbjct: 20 FPQEKLNEIFKDDVFVVIGYGTQGRNQSRNLRDKGFKVIVGLR-KGPSWDLAKEDGWVES 78
Query: 66 -EVYTIEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQ---IV 121
++ I EA ++ I+ L+ D Q + E L G+ L FSHGF+I +K+ +V
Sbjct: 79 ESLFEITEACQKGTIIMYLLSDAGQKACWNTIKE--LVHGKTLYFSHGFSIVFKEKTGVV 136
Query: 122 PPEYVDVIMVAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAG 181
PPE DVIMVAPK G VR +LEG G+ + VAV+Q+++G A++ A A AIG
Sbjct: 137 PPEDCDVIMVAPKGSGTTVRTLFLEGRGINSSVAVFQNWSGKAEERAYAAGIAIG--SGY 194
Query: 182 VIETTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEA-KLIMD 240
+ TTF+ ET SDL GE+ L+G + K FEVL+ G+ P A+ E EA + +
Sbjct: 195 LYPTTFERETYSDLTGERGTLMGCIQGCFKAQFEVLIANGHTPSEAFSETVEEATQSLYP 254
Query: 241 LIYERGFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWI---SK 297
LI + G M S TA+ G L K K ++ E VR+G A+ + SK
Sbjct: 255 LIGKDGMDWMYDNCSTTARRGALDWMDKFY-AATKPVFEELYESVRNGTEAENTLVANSK 313
Query: 298 ADKASEVLEELMKPIEEHEIEKVGRFIRKM 327
D + +EL K + E ++ + +R +
Sbjct: 314 PDYRENLAKEL-KELRESQMWQTAVTVRSL 342
>gb|AAF13803.1|AF130813_3 (AF130813) acetohydroxy acid isomeroreductase [Buchnera aphidicola]
Length = 489
Score = 164 bits (410), Expect = 2e-39
Identities = 113/311 (36%), Positives = 165/311 (52%), Gaps = 9/311 (2%)
Query: 16 DILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSG-----SSWKRAEKDGFEVYTI 70
DILK K + ++G G+QG Q NMRDSG+HV LR S SW+ A K+ F V T
Sbjct: 32 DILKRKNIVIVGCGSQGLNQGLNMRDSGLHVSYALRGSSILNKNKSWENATKNNFFVDTY 91
Query: 71 EEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPPEYVDVIM 130
E + AD+V L PD + +V ++ +++E LGFSHGF+I + VIM
Sbjct: 92 ENIIPTADLVINLTPDKQRKEVVTL-LQKFMKENSVLGFSHGFHIVEIGQKIRNDITVIM 150
Query: 131 VAPKSPGKRVREKYLEGFGVPALVAVY--QDYTGNAKDLALAMAKAIGCTRAGVIETTFK 188
VAPK PG VRE+Y +GFGVP+L+AV+ D ++A A A ++G RAGV+ ++F
Sbjct: 151 VAPKCPGTEVREEYKKGFGVPSLIAVHMENDPKKIGFEIAKAWAYSLGSHRAGVLHSSFI 210
Query: 189 DETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMDLIYERGFT 248
E +SDL+GEQ +L G L ++ LV G P A + I + + G T
Sbjct: 211 AEVKSDLMGEQTILCGMLQTSSLVCYDQLVSQGKDPNYAGKLIQLGWESITESVKHGGIT 270
Query: 249 GMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADKASEVLEEL 308
ML +S+TAK + K + +K + + SGEF+K I + + L+E
Sbjct: 271 LMLNRLSNTAKIRAYILSKK-LKVMFSSLFRKHMDDIISGEFSKNMIDDWNSDDKKLKEW 329
Query: 309 MKPIEEHEIEK 319
I++ + EK
Sbjct: 330 RTQIKKTDFEK 340
>sp|P05793|ILVC_ECOLI KETOL-ACID REDUCTOISOMERASE (ACETOHYDROXY-ACID ISOMEROREDUCTASE)
(ALPHA-KETO-BETA-HYDROXYLACIL REDUCTOISOMERASE)
>gi|7427678|pir||ISECKR ketol-acid reductoisomerase (EC
1.1.1.86) - Escherichia coli (strain K-12)
>gi|148181|gb|AAA67577.1| (M87049) ketol-acid
reductoisomerase [Escherichia coli]
>gi|1790210|gb|AAC76779.1| (AE000454) ketol-acid
reductoisomerase [Escherichia coli K12]
Length = 491
Score = 163 bits (408), Expect = 3e-39
Identities = 116/310 (37%), Positives = 168/310 (53%), Gaps = 25/310 (8%)
Query: 18 LKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSG-----SSWKRAEKDGFEVYTIEE 72
L+ K V ++G G QG Q NMRDSG+ + LR +SW++A ++GF+V T EE
Sbjct: 35 LQGKKVVIVGCGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEE 94
Query: 73 AVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPPEYVDVIMVA 132
+ +AD+V L PD V R ++P +++G ALG+SHGFNI + + V+MVA
Sbjct: 95 LIPQADLVINLTPDKQHSDVVRT-VQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVA 153
Query: 133 PKSPGKRVREKYLEGFGVPALVAVY--QDYTGNAKDLALAMAKAIGCTRAGVIETTFKDE 190
PK PG VRE+Y GFGVP L+AV+ D G +A A A A G RAGV+E++F E
Sbjct: 154 PKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAE 213
Query: 191 TESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEA--KLIMDLIYERGFT 248
+SDL+GEQ +L G L F+ LVE G P AY E + + I + + + G T
Sbjct: 214 VKSDLMGEQTILCGMLQAGSLLCFDKLVEEGTDP--AYAEKLIQFGWETITEALKQGGIT 271
Query: 249 GMLKAVSDTAKYGGLTVGPKVIDDHVKENM----KKFAERVRSGEFAK----EWISKADK 300
M+ +S+ AK + + + +KE M +K + + SGEF+ +W + K
Sbjct: 272 LMMDRLSNPAK-----LRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMADWANDDKK 326
Query: 301 ASEVLEELMK 310
EE K
Sbjct: 327 LLTWREETGK 336
>gb|AAA24029.1| (M11689) acetohydroxy acid isomeroreductase [Escherichia coli]
Length = 491
Score = 162 bits (407), Expect = 4e-39
Identities = 114/308 (37%), Positives = 165/308 (53%), Gaps = 21/308 (6%)
Query: 18 LKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSG-----SSWKRAEKDGFEVYTIEE 72
L+ K V ++G G QG Q NMRDSG+ + LR +SW++A ++GF+V T EE
Sbjct: 35 LQGKKVVIVGCGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEE 94
Query: 73 AVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPPEYVDVIMVA 132
+ +AD+V L PD V R ++P +++G ALG+SHGFNI + + V+MVA
Sbjct: 95 LIPQADLVINLTPDKQHSDVVRT-VQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVA 153
Query: 133 PKSPGKRVREKYLEGFGVPALVAVY--QDYTGNAKDLALAMAKAIGCTRAGVIETTFKDE 190
PK PG VRE+Y GFGVP L+AV+ D G +A A A A G RAGV+E++F E
Sbjct: 154 PKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAE 213
Query: 191 TESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMDLIYERGFTGM 250
+SDL+GEQ +L G L F+ LVE G P A + I + + + G T M
Sbjct: 214 VKSDLMGEQTILCGMLQAGSLLCFDKLVEEGTDPAYAKKLIQFGWETITEALKQGGITLM 273
Query: 251 LKAVSDTAKYGGLTVGPKVIDDHVKENM----KKFAERVRSGEFAK----EWISKADKAS 302
+ +S+ AK + + + +KE M +K + + SGEF+ +W + K
Sbjct: 274 MDRLSNPAK-----LRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMADWANDDKKLL 328
Query: 303 EVLEELMK 310
EE K
Sbjct: 329 TWREETGK 336
>gb|AAF33476.1| (AF233324) S. typhimurium ketol-acid reductoisomerase (ILVC)
(SP:P05989); contains similarity to Pfam family PF01450
(Acetohydroxy acid isomeroreductase), score=628.8,
E=3.1e-185, N=1 [Salmonella typhimurium LT2]
Length = 491
Score = 161 bits (403), Expect = 1e-38
Identities = 115/310 (37%), Positives = 167/310 (53%), Gaps = 25/310 (8%)
Query: 18 LKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSG-----SSWKRAEKDGFEVYTIEE 72
L+ K V ++G G QG Q NMRDSG+ + LR +SW++A ++GF+V T EE
Sbjct: 35 LQGKKVVIVGCGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEE 94
Query: 73 AVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPPEYVDVIMVA 132
+ +AD+V L PD V R ++P +++G ALG+SHGFNI + + V+MVA
Sbjct: 95 LIPQADLVVNLTPDKQHSDVVRS-VQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVA 153
Query: 133 PKSPGKRVREKYLEGFGVPALVAVY--QDYTGNAKDLALAMAKAIGCTRAGVIETTFKDE 190
PK PG VRE+Y GFGVP L+AV+ D G +A A A A G RAGV+E++F E
Sbjct: 154 PKCPGTEVREEYKRGFGVPTLIAVHPENDPQGEGMAIAKAWAAATGGHRAGVLESSFVAE 213
Query: 191 TESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEA--KLIMDLIYERGFT 248
+SDL+GEQ +L G L F+ LV G P AY E + + I + + + G T
Sbjct: 214 VKSDLMGEQTILCGMLQAGSLLCFDKLVAEGTDP--AYAEKLIQFGWETITEALKQGGIT 271
Query: 249 GMLKAVSDTAKYGGLTVGPKVIDDHVKENM----KKFAERVRSGEFAK----EWISKADK 300
M+ +S+ AK + + + +KE M +K + + SGEF+ +W + K
Sbjct: 272 LMMDRLSNPAK-----LRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMADWANDDKK 326
Query: 301 ASEVLEELMK 310
EE K
Sbjct: 327 LLTWREETGK 336
>gb|AAF13807.1|AF130814_3 (AF130814) acetohydroxy acid isomeroreductase [Buchnera aphidicola]
Length = 490
Score = 153 bits (382), Expect = 3e-36
Identities = 105/321 (32%), Positives = 163/321 (50%), Gaps = 13/321 (4%)
Query: 16 DILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSG-----SSWKRAEKDGFEVYTI 70
++LK K + ++G G+QG Q NMRDSG+++ LR SW A +GF V T
Sbjct: 33 NVLKGKNIVIVGCGSQGLNQGLNMRDSGLNISYALRDDSIFNKNQSWINATSNGFFVGTY 92
Query: 71 EEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPPEYVDVIM 130
E + AD+V L PD +V ++ +++ LGFSHGFNI + + VIM
Sbjct: 93 ENIIPTADLVINLTPDKQHEQVVNV-LQKFMKPNSVLGFSHGFNIVEVGQLIRNDITVIM 151
Query: 131 VAPKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAK----AIGCTRAGVIETT 186
VAPK PG VRE+Y GFGVPAL+AV+ + + D+ +AK +IG AG++ ++
Sbjct: 152 VAPKCPGTEVREEYKRGFGVPALIAVHSE--NDPHDIGFEIAKSWAISIGSHHAGILHSS 209
Query: 187 FKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMDLIYERG 246
F E +SDL+GEQ +L G L + L+ G P A ++I + + G
Sbjct: 210 FIAEVKSDLMGEQTILCGMLQASSLVCYNQLIFQGVNPSYAGKLIQTGWEVITESVKHGG 269
Query: 247 FTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADKASEVLE 306
T ML +S+TAK + K + +K + + SGEF+K + + L+
Sbjct: 270 ITLMLDRLSNTAKIRAYFLSKK-LKKIFFPLFRKHMDDIISGEFSKNMMFDWKNNDQQLK 328
Query: 307 ELMKPIEEHEIEKVGRFIRKM 327
E I+ + EK + +++
Sbjct: 329 EWRTEIQNTDFEKCNIYYKQI 349
>sp|O51888|ILVC_BUCAP KETOL-ACID REDUCTOISOMERASE (ACETOHYDROXY-ACID ISOMEROREDUCTASE)
(ALPHA-KETO-BETA-HYDROXYLACIL REDUCTOISOMERASE)
>gi|2827034|gb|AAC38126.1| (AF008210) acetohydroxy acid
isomeroreductase [Buchnera aphidicola]
Length = 491
Score = 152 bits (381), Expect = 4e-36
Identities = 102/286 (35%), Positives = 155/286 (53%), Gaps = 13/286 (4%)
Query: 17 ILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSG-----SSWKRAEKDGFEVYTIE 71
ILK K + ++G G+QG QA NMRDSG+++ L+ + SSW A K+ FEV E
Sbjct: 33 ILKIKKIVIVGCGSQGLNQALNMRDSGLNISFALKKNSILRKNSSWLNATKNNFEVNDYE 92
Query: 72 EAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPPEYVDVIMV 131
+ AD+V L PD V +E ++ +++ LG+SHGFNI + + + V+MV
Sbjct: 93 SLIPNADLVINLTPDKQHENVVKE-LQKLMKKNSCLGYSHGFNIVECGEIIRKDITVVMV 151
Query: 132 APKSPGKRVREKYLEGFGVPALVAVYQDYTGNAKDLALAMAKA----IGCTRAGVIETTF 187
APK PG VRE++ GFGVP L+AV+ + + K + L +AKA G RAGV+E++F
Sbjct: 152 APKCPGTEVREEFKRGFGVPTLIAVHTE--NDPKKIGLEIAKAWAFSTGGHRAGVLESSF 209
Query: 188 KDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMDLIYERGF 247
E +SDL+GEQ +L G L +E L++ + P A + I + + G
Sbjct: 210 IAEVKSDLMGEQTILCGLLQTASLICYEKLIKDKHNPSYAAKLIQYGWETITESLKHGGI 269
Query: 248 TGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKE 293
T M+ +S+ +K + K I + KK + + SG F+KE
Sbjct: 270 TLMMDRLSNPSKIKAFKISKK-IKKILSPLFKKHMDDIISGSFSKE 314
>sp|P44822|ILVC_HAEIN KETOL-ACID REDUCTOISOMERASE (ACETOHYDROXY-ACID ISOMEROREDUCTASE)
(ALPHA-KETO-BETA-HYDROXYLACIL REDUCTOISOMERASE)
>gi|1074946|pir||B64086 ketol-acid reductoisomerase (EC
1.1.1.86) - Haemophilus influenzae (strain Rd KW20)
>gi|1573684|gb|AAC22342.1| (U32751) ketol-acid
reductoisomerase (ilvC) [Haemophilus influenzae Rd]
Length = 492
Score = 151 bits (378), Expect = 9e-36
Identities = 103/287 (35%), Positives = 155/287 (53%), Gaps = 17/287 (5%)
Query: 16 DILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSG-----SSWKRAEKDGFEVYTI 70
+ LK K + ++G G QG Q NMRDSG+ + LRP +S++RA ++GF+V T
Sbjct: 33 NFLKGKKIVIVGCGAQGLNQGLNMRDSGLDISYALRPEAIAEKRASFQRATENGFKVGTY 92
Query: 71 EEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPPEYVDVIM 130
EE + AD+V L PD KV + + P +++ A G+SHGFNI + + V+M
Sbjct: 93 EELIPTADLVVNLTPDKQHSKVVAD-VMPLMKKDSAFGYSHGFNIVEVGEEIRKDITVVM 151
Query: 131 VAPKSPGKRVREKYLEGFGVPALVAVY--QDYTGNAKDLALAMAKAIGCTRAGVIETTFK 188
VAPK PG VRE+Y GFGVP L+AV+ D G +A A A A G +AGV+E++F
Sbjct: 152 VAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHKAGVLESSFV 211
Query: 189 DETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMDLIYERGFT 248
E +SDL+GEQ +L G L ++ LV G P A + I + + + G T
Sbjct: 212 AEVKSDLMGEQTILCGMLQAGSIVCYDKLVADGKDPAYAGKLIQYGWETITEALKQGGIT 271
Query: 249 GMLKAVSDTAKYGGLTVGPKVIDDHVKENM----KKFAERVRSGEFA 291
M+ +S++AK + + +KE++ K + + SG F+
Sbjct: 272 LMMDRLSNSAKLRAFELA-----EQIKESLGFLYYKHMDDIISGHFS 313
>pir||G82356 ketol-acid reductoisomerase VC0162 [imported] - Vibrio cholerae
(group O1 strain N16961) >gi|9654564|gb|AAF93338.1|
(AE004106) ketol-acid reductoisomerase [Vibrio cholerae]
Length = 494
Score = 151 bits (377), Expect = 1e-35
Identities = 107/317 (33%), Positives = 164/317 (50%), Gaps = 54/317 (17%)
Query: 16 DILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSG-----SSWKRAEKDGFEVYTI 70
D LK K V ++G G QG Q NMRDSG+ V LR + S+K A+ +GF V +
Sbjct: 33 DYLKGKKVVIVGCGAQGLNQGLNMRDSGLDVSYALRQAAIDEQRQSFKNAKNNGFNVGSY 92
Query: 71 EEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPPEYVDVIM 130
E+ + AD+V L PD V + P +++G ALG+SHGFNI + + + + V+M
Sbjct: 93 EQLIPTADLVINLTPDKQHTSVVNA-VMPLMKQGAALGYSHGFNIVEEGMQIRKDITVVM 151
Query: 131 VAPKSPGKRVREKYLEGFGVPALVAVY--QDYTGNAKDLALAMAKAIGCTRAGVIETTFK 188
VAPK PG VRE+Y GFGVP L+AV+ D G ++A A A A G RAG + ++F
Sbjct: 152 VAPKCPGTEVREEYKRGFGVPTLIAVHPENDPQGEGWEIAKAWAAATGGHRAGCLASSFV 211
Query: 189 DETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMDLIYERGFT 248
E +SDL+GEQ +L G +++ G V E K++ D I + G+
Sbjct: 212 AEVKSDLMGEQTILCG----MLQAGSIVCYE----------------KMVADGI-DPGYA 250
Query: 249 GML-----KAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWISKADKASE 303
G L + +++ K+GG+T H+ + + A+ KA + SE
Sbjct: 251 GKLLQFGWETITEALKFGGIT--------HMMDRLSNPAK------------IKAFELSE 290
Query: 304 VLEELMKPIEEHEIEKV 320
L++LM+P+ ++ +
Sbjct: 291 ELKDLMRPLYNKHMDDI 307
>gb|AAF13799.1|AF130812_3 (AF130812) acetohydroxy acid isomeroreductase [Buchnera aphidicola]
Length = 489
Score = 148 bits (369), Expect = 1e-34
Identities = 101/291 (34%), Positives = 157/291 (53%), Gaps = 17/291 (5%)
Query: 16 DILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSG-----SSWKRAEKDGFEVYTI 70
+ILK+K + ++G G+QG Q NMRDSG+++ LR + SW A K+ F V
Sbjct: 32 EILKNKKIVIVGCGSQGLNQGLNMRDSGLNISYALRKNSILKKNQSWINATKNNFLVGDY 91
Query: 71 EEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPPEYVDVIM 130
E + AD+V L PD V +E ++ +++ LG+SHGFNI K + + VIM
Sbjct: 92 ESLIPNADLVINLTPDKQHSNVVKE-LQKLMKKDACLGYSHGFNIVEKLRNIRKDITVIM 150
Query: 131 VAPKSPGKRVREKYLEGFGVPALVAVY--QDYTGNAKDLALAMAKAIGCTRAGVIETTFK 188
VAPK PG VRE+Y GFGV L+AV+ DY+ ++A A A + G RAGV+E++F
Sbjct: 151 VAPKCPGTEVREEYKRGFGVGTLIAVHNENDYSNMGLEVAKAWAFSTGGHRAGVLESSFV 210
Query: 189 DETESDLIGEQLVLVGGLIELIKKGFEVLVEL----GYPPELAYFEACNEAKLIMDLIYE 244
E +SDL+GEQ +L G L +E L+ GY +L F + I + +
Sbjct: 211 AEVKSDLMGEQTILCGMLQTASLVCYEKLITTQNHPGYAGKLIQF----GWETITESLKH 266
Query: 245 RGFTGMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKEWI 295
G T M+ +S+++K + + I + + +K + + SG+F+ + I
Sbjct: 267 GGITLMMDRLSNSSKIRAFKLSQE-IKEFSQNLFQKHMDDIISGDFSSKMI 316
>sp|P57655|ILVC_BUCAI KETOL-ACID REDUCTOISOMERASE (ACETOHYDROXY-ACID ISOMEROREDUCTASE)
(ALPHA-KETO-BETA-HYDROXYLACIL REDUCTOISOMERASE)
>gi|10039250|dbj|BAB13284.1| (AP001119) ketol-acid
reductoisomerase [Buchnera sp. APS]
Length = 490
Score = 139 bits (348), Expect = 3e-32
Identities = 96/285 (33%), Positives = 152/285 (52%), Gaps = 9/285 (3%)
Query: 16 DILKDKTVAVIGYGNQGEAQAKNMRDSGVHVILGLRPSG-----SSWKRAEKDGFEVYTI 70
DILK+K + ++G G QG Q NMRD+G+++ L+ + SW A ++ F+V
Sbjct: 32 DILKNKNIVIVGCGAQGLNQGLNMRDAGLNISYALKKNSIANKNQSWINAIENNFKVDDY 91
Query: 71 EEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVPPEYVDVIM 130
+ + AD+V L PD V ++ ++ +++ LG+SHGFNI + + VIM
Sbjct: 92 DALIPDADLVINLTPDKQHHSVIKK-LQKLMKKNAVLGYSHGFNIVEFGEKIRKDITVIM 150
Query: 131 VAPKSPGKRVREKYLEGFGVPALVAVYQDYTGN--AKDLALAMAKAIGCTRAGVIETTFK 188
VAPK PG VRE+Y GFGVP L+AV+ + N ++A A A + G RAGV+E++F
Sbjct: 151 VAPKCPGTEVREEYKRGFGVPTLIAVHHENDINKIGLEVAKAWAFSTGGHRAGVLESSFI 210
Query: 189 DETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMDLIYERGFT 248
E +SDL+GEQ +L G L +E L+ P + N + I + + G T
Sbjct: 211 AEVKSDLMGEQTILCGMLQTASLLCYEKLITEKCNPAYSAKLIQNGWETITESLKHGGIT 270
Query: 249 GMLKAVSDTAKYGGLTVGPKVIDDHVKENMKKFAERVRSGEFAKE 293
M+ +S+++K + K I + +K + + SGEF+ E
Sbjct: 271 LMMDRLSNSSKIRAYKLS-KEIKKILSPLFQKHMDDIISGEFSNE 314
>sp|O82043|ILV5_PEA KETOL-ACID REDUCTOISOMERASE PRECURSOR (ACETOHYDROXY-ACID
REDUCTOISOMERASE) (ALPHA-KETO-BETA-HYDROXYLACIL
REDUCTOISOMERASE) >gi|7431346|pir||T06825 ketol-acid
reductoisomerase (EC 1.1.1.86) - garden pea
>gi|3452497|emb|CAA76854.1| (Y17796) ketol-acid
reductoisomerase [Pisum sativum]
Length = 581
Score = 113 bits (279), Expect = 4e-24
Identities = 85/259 (32%), Positives = 129/259 (48%), Gaps = 23/259 (8%)
Query: 21 KTVAVIGYGNQGEAQAKNMRDSGVH------VILGLRPSGSSWKRAEKDGFE-----VYT 69
K + VIG+G+QG AQA+N+RDS V V +GLR SS+ A + GF +
Sbjct: 110 KQIGVIGWGSQGPAQAQNLRDSLVEAKSDIVVKVGLRKGSSSFNEAREAGFSEEKGTLGD 169
Query: 70 IEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVP---PEYV 126
I E + +D+V +LI D Q Y E I +L+ LG SHGF + + Q + P+
Sbjct: 170 IWETISGSDLVLLLISDSAQADNY-EKIFSHLKPNSILGLSHGFLLGHLQSIGLDFPKNF 228
Query: 127 DVIMVAPKSPGKRVREKYLE-----GFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAG 181
VI V PK G VR Y++ G G+ + V+QD G A ++AL + A+G
Sbjct: 229 SVIAVCPKGMGPSVRRLYVQGKEINGAGINSSFGVHQDVDGRATNVALGWSVALG--SPF 286
Query: 182 VIETTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNE-AKLIMD 240
TT + E +SD+ GE+ +L+G + +++ F E G +LAY +I
Sbjct: 287 TFATTLEQEYKSDIFGERGILLGAVHGIVESLFRRYTENGMSEDLAYKNTVESITGVISK 346
Query: 241 LIYERGFTGMLKAVSDTAK 259
I +G + A+S+ K
Sbjct: 347 TISTQGMLAVYNALSEDGK 365
>pir||S36884 ketol-acid reductoisomerase (EC 1.1.1.86) - Arabidopsis thaliana
>gi|11251579|pir||T45681 ketol-acid reductoisomerase -
Arabidopsis thaliana >gi|402552|emb|CAA49506.1| (X69880)
ketol-acid reductoisomerase [Arabidopsis thaliana]
>gi|6735378|emb|CAB68199.1| (AL137082) ketol-acid
reductoisomerase [Arabidopsis thaliana]
Length = 591
Score = 111 bits (275), Expect = 1e-23
Identities = 79/227 (34%), Positives = 118/227 (51%), Gaps = 22/227 (9%)
Query: 21 KTVAVIGYGNQGEAQAKNMRDSGVH------VILGLRPSGSSWKRAEKDGF-----EVYT 69
K + VIG+G+QG AQA+N+RDS V V +GLR S++ A GF +
Sbjct: 120 KQIGVIGWGSQGPAQAQNLRDSLVEAKSDIVVKIGLRKGSRSFEEARAAGFTEESGTLGD 179
Query: 70 IEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQ---IVPPEYV 126
I E + +D+V +LI D Q Y E I +++ LG SHGF + + Q + P+ +
Sbjct: 180 IWETIAGSDLVLLLISDAAQADNY-EKIFSHMKPNSILGLSHGFLLGHLQSSGLDFPKNI 238
Query: 127 DVIMVAPKSPGKRVREKYLE-----GFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAG 181
V+ V PK G VR Y++ G G+ A AV+QD G A D+AL + A+G
Sbjct: 239 SVVAVCPKGMGPSVRRLYVQGKEINGAGINASFAVHQDVDGRAADVALGWSVALG--SPF 296
Query: 182 VIETTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAY 228
TT + E SD+ GE+ +L+G + +++ F E G +LAY
Sbjct: 297 TFATTLEQEYRSDIFGERGILLGAVHGIVESLFRRYTENGMSEDLAY 343
>pir||S30145 ketol-acid reductoisomerase (EC 1.1.1.86) precursor - Arabidopsis
thaliana
Length = 591
Score = 111 bits (275), Expect = 1e-23
Identities = 79/227 (34%), Positives = 118/227 (51%), Gaps = 22/227 (9%)
Query: 21 KTVAVIGYGNQGEAQAKNMRDSGVH------VILGLRPSGSSWKRAEKDGF-----EVYT 69
K + VIG+G+QG AQA+N+RDS V V +GLR S++ A GF +
Sbjct: 120 KQIGVIGWGSQGPAQAQNLRDSLVEAKSDIVVKIGLRKGSRSFEEARAAGFTEESGTLGD 179
Query: 70 IEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQ---IVPPEYV 126
I E + +D+V +LI D Q Y E I +++ LG SHGF + + Q + P+ +
Sbjct: 180 IWETIAGSDLVLLLISDAAQADNY-EKIFSHMKPNSILGLSHGFLLGHLQSSGLDFPKNI 238
Query: 127 DVIMVAPKSPGKRVREKYLE-----GFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAG 181
V+ V PK G VR Y++ G G+ A AV+QD G A D+AL + A+G
Sbjct: 239 SVVAVCPKGMGPSVRRLYVQGKEINGAGINASFAVHQDVDGRAADVALGWSVALG--SPF 296
Query: 182 VIETTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAY 228
TT + E SD+ GE+ +L+G + +++ F E G +LAY
Sbjct: 297 TFATTLEQEYRSDIFGERGILLGAVHGIVESLFRRYTENGMSEDLAY 343
>sp|Q05758|ILV5_ARATH KETOL-ACID REDUCTOISOMERASE PRECURSOR (ACETOHYDROXY-ACID
REDUCTOISOMERASE) (ALPHA-KETO-BETA-HYDROXYLACIL
REDUCTOISOMERASE) >gi|288063|emb|CAA48253.1| (X68150)
ketol-acid reductoisomerase [Arabidopsis thaliana]
Length = 591
Score = 109 bits (270), Expect = 4e-23
Identities = 78/227 (34%), Positives = 117/227 (51%), Gaps = 22/227 (9%)
Query: 21 KTVAVIGYGNQGEAQAKNMRDSGVH------VILGLRPSGSSWKRAEKDGF-----EVYT 69
K + VIG+G+QG AQA+N+RDS V V +GLR S++ A GF +
Sbjct: 120 KQIGVIGWGSQGPAQAQNLRDSLVEAKSDIVVKIGLRKGSRSFEEARAAGFTEESGTLGD 179
Query: 70 IEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQ---IVPPEYV 126
I E + +D+V +LI D Q Y E I +++ LG SHGF + + Q + P+ +
Sbjct: 180 IWETIAGSDLVLLLISDAAQADNY-EKIFSHMKPNSILGLSHGFLLGHLQSSGLDFPKNI 238
Query: 127 DVIMVAPKSPGKRVREKYLE-----GFGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAG 181
V+ V PK G VR Y++ G G+ A AV+QD G A D+ L + A+G
Sbjct: 239 SVVAVCPKGMGPSVRRLYVQGKEINGAGINASFAVHQDVDGRAADVRLGWSVALG--SPF 296
Query: 182 VIETTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAY 228
TT + E SD+ GE+ +L+G + +++ F E G +LAY
Sbjct: 297 TFATTLEQEYRSDIFGERGILLGAVHGIVESLFRRYTENGMSEDLAY 343
>emb|CAB61890.1| (AJ251333) acetohydroxy acid isomeroreductase [Pisum sativum]
Length = 581
Score = 107 bits (265), Expect = 2e-22
Identities = 83/259 (32%), Positives = 127/259 (48%), Gaps = 23/259 (8%)
Query: 21 KTVAVIGYGNQGEAQAKNMRDSGVH------VILGLRPSGSSWKRAEKDGFE-----VYT 69
K + IG+G+QG AQA+N+RDS V V +GLR SS+ A + GF +
Sbjct: 110 KQIGGIGWGSQGPAQAQNLRDSLVEAKSDIVVKVGLRKGSSSFNEAREAGFSEEKGTLGD 169
Query: 70 IEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVP---PEYV 126
I E + +D+ +LI D Q Y E I +L+ LG SHGF + + Q + P+
Sbjct: 170 IWETISGSDLGLLLISDSAQADNY-EKIFSHLKPNSILGLSHGFLLGHLQSIGLDFPKNF 228
Query: 127 DVIMVAPKSPGKRVREKYLEG-----FGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAG 181
VI V PK G VR Y++G G+ + V+QD G A ++AL + A+G
Sbjct: 229 SVIAVCPKGMGPSVRRLYVQGKEINGAGINSSFGVHQDVDGRATNVALGWSVALGSPFT- 287
Query: 182 VIETTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNE-AKLIMD 240
TT + E +SD+ GE+ +L+G + +++ F E G +LAY +I
Sbjct: 288 -FATTLEQEYKSDIFGERGILLGAVHGIVESLFRRYTENGMSEDLAYKNTVESITGVISK 346
Query: 241 LIYERGFTGMLKAVSDTAK 259
I +G + A+S+ K
Sbjct: 347 TISTQGMLAVYNALSEDGK 365
>sp|Q01292|ILV5_SPIOL KETOL-ACID REDUCTOISOMERASE PRECURSOR (ACETOHYDROXY-ACID
REDUCTOISOMERASE) (ALPHA-KETO-BETA-HYDROXYLACIL
REDUCTOISOMERASE) >gi|81509|pir||S17180 ketol-acid
reductoisomerase (EC 1.1.1.86) precursor - spinach
>gi|21234|emb|CAA40356.1| (X57073) ketol-acid
reductoisomerase [Spinacia oleracea]
Length = 595
Score = 106 bits (263), Expect = 3e-22
Identities = 80/259 (30%), Positives = 129/259 (48%), Gaps = 23/259 (8%)
Query: 21 KTVAVIGYGNQGEAQAKNMRDS------GVHVILGLRPSGSSWKRAEKDGFE-----VYT 69
K + VIG+G+Q AQA+N++DS V V +GLR +S+ A GF +
Sbjct: 126 KQIGVIGWGSQAPAQAQNLKDSLTEAKSDVVVKIGLRKGSNSFAEARAAGFSEENGTLGD 185
Query: 70 IEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVP---PEYV 126
+ E + +D+V +LI D Q Y E + +++ LG SHGF + + Q + P+ +
Sbjct: 186 MWETISGSDLVLLLISDSAQADNY-EKVFSHMKPNSILGLSHGFLLGHLQSLGQDFPKNI 244
Query: 127 DVIMVAPKSPGKRVREKYLEG-----FGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAG 181
VI V PK G VR Y++G G+ + AV+QD G A D+AL + A+G
Sbjct: 245 SVIAVCPKGMGPSVRRLYVQGKEVNGAGINSSFAVHQDVDGRATDVALGWSIALGSPFT- 303
Query: 182 VIETTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACN-EAKLIMD 240
TT + E +SD+ GE+ +L+G + +++ F E G +LAY +I
Sbjct: 304 -FATTLEQEYKSDIFGERGILLGAVHGIVECLFRRYTESGMSEDLAYKNTVECITGVISK 362
Query: 241 LIYERGFTGMLKAVSDTAK 259
I +G + ++S+ K
Sbjct: 363 TISTKGMLALYNSLSEEGK 381
>pdb|1QMG|A Chain A, Acetohydroxyacid Isomeroreductase Complexed With Its
Reaction Product Dihydroxy-Methylvalerate, Manganese And
Adp-Ribose. >gi|7546311|pdb|1QMG|D Chain D,
Acetohydroxyacid Isomeroreductase Complexed With Its
Reaction Product Dihydroxy-Methylvalerate, Manganese And
Adp-Ribose. >gi|2554835|pdb|1YVE|I Chain I, Acetohydroxy
Acid Isomeroreductase Complexed With Nadph, Magnesium
And Inhibitor Ipoha (N-Hydroxy-N- Isopropyloxamate)
>gi|2554838|pdb|1YVE|L Chain L, Acetohydroxy Acid
Isomeroreductase Complexed With Nadph, Magnesium And
Inhibitor Ipoha (N-Hydroxy-N- Isopropyloxamate)
>gi|7546310|pdb|1QMG|C Chain C, Acetohydroxyacid
Isomeroreductase Complexed With Its Reaction Product
Dihydroxy-Methylvalerate, Manganese And Adp-Ribose.
>gi|7546309|pdb|1QMG|B Chain B, Acetohydroxyacid
Isomeroreductase Complexed With Its Reaction Product
Dihydroxy-Methylvalerate, Manganese And Adp-Ribose.
>gi|2554836|pdb|1YVE|J Chain J, Acetohydroxy Acid
Isomeroreductase Complexed With Nadph, Magnesium And
Inhibitor Ipoha (N-Hydroxy-N- Isopropyloxamate)
>gi|2554837|pdb|1YVE|K Chain K, Acetohydroxy Acid
Isomeroreductase Complexed With Nadph, Magnesium And
Inhibitor Ipoha (N-Hydroxy-N- Isopropyloxamate)
Length = 524
Score = 106 bits (263), Expect = 3e-22
Identities = 80/259 (30%), Positives = 129/259 (48%), Gaps = 23/259 (8%)
Query: 21 KTVAVIGYGNQGEAQAKNMRDS------GVHVILGLRPSGSSWKRAEKDGFE-----VYT 69
K + VIG+G+Q AQA+N++DS V V +GLR +S+ A GF +
Sbjct: 55 KQIGVIGWGSQAPAQAQNLKDSLTEAKSDVVVKIGLRKGSNSFAEARAAGFSEENGTLGD 114
Query: 70 IEEAVKRADIVHILIPDLVQPKVYREHIEPYLREGQALGFSHGFNIHYKQIVP---PEYV 126
+ E + +D+V +LI D Q Y E + +++ LG SHGF + + Q + P+ +
Sbjct: 115 MWETISGSDLVLLLISDSAQADNY-EKVFSHMKPNSILGLSHGFLLGHLQSLGQDFPKNI 173
Query: 127 DVIMVAPKSPGKRVREKYLEG-----FGVPALVAVYQDYTGNAKDLALAMAKAIGCTRAG 181
VI V PK G VR Y++G G+ + AV+QD G A D+AL + A+G
Sbjct: 174 SVIAVCPKGMGPSVRRLYVQGKEVNGAGINSSFAVHQDVDGRATDVALGWSIALGSPFT- 232
Query: 182 VIETTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACN-EAKLIMD 240
TT + E +SD+ GE+ +L+G + +++ F E G +LAY +I
Sbjct: 233 -FATTLEQEYKSDIFGERGILLGAVHGIVECLFRRYTESGMSEDLAYKNTVECITGVISK 291
Query: 241 LIYERGFTGMLKAVSDTAK 259
I +G + ++S+ K
Sbjct: 292 TISTKGMLALYNSLSEEGK 310
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.318 0.138 0.393
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 126119579
Number of Sequences: 2977
Number of extensions: 5407872
Number of successful extensions: 15527
Number of sequences better than 1.0e-10: 61
Number of HSP's better than 0.0 without gapping: 36
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 15357
Number of HSP's gapped (non-prelim): 75
length of query: 332
length of database: 189,106,746
effective HSP length: 57
effective length of query: 275
effective length of database: 154,992,987
effective search space: 42623071425
effective search space used: 42623071425
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.6 bits)
S2: 165 (68.7 bits)