BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0892 (leuD-1) DE:3-isopropylmalate dehydratase, small
subunit (leuD-1)
(164 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||C75045 3-isopropylmalate dehydratase, small chain (leud-1) ... 335 2e-91
pir||E70421 3-isopropylmalate dehydratase - Aquifex aeolicus >gi... 228 4e-59
sp|O67399|LEUD_AQUAE 3-ISOPROPYLMALATE DEHYDRATASE SMALL SUBUNIT... 228 4e-59
gi|11498237 3-isopropylmalate dehydratase, small subunit (leuD-1... 215 2e-55
sp|Q58673|LE24_METJA PUTATIVE 3-ISOPROPYLMALATE DEHYDRATASE SMAL... 215 3e-55
sp|Q9WZ25|LEUD_THEMA 3-ISOPROPYLMALATE DEHYDRATASE SMALL SUBUNIT... 209 2e-53
sp|O27440|LE24_METTH PUTATIVE 3-ISOPROPYLMALATE DEHYDRATASE SMAL... 198 3e-50
gi|11499350 3-isopropylmalate dehydratase, small subunit (leuD-2... 194 5e-49
pir||D72394 hypothetical protein TM0292 - Thermotoga maritima (s... 194 7e-49
sp|O26917|LE23_METTH PUTATIVE 3-ISOPROPYLMALATE DEHYDRATASE SMAL... 193 1e-48
pir||A75160 3-isopropylmalate dehydratase, small chain (leud-2) ... 166 2e-40
sp|Q58667|LE23_METJA PUTATIVE 3-ISOPROPYLMALATE DEHYDRATASE SMAL... 163 1e-39
gb|AAK42607.1| 3-isopropylmalate dehydratase, small subunit (iso... 162 2e-39
sp|O59393|LEUD_PYRHO PUTATIVE 3-ISOPROPYLMALATE DEHYDRATASE SMAL... 161 6e-39
pir||F75355 3-isopropylmalate dehydratase, small subunit - Deino... 150 9e-36
dbj|BAA74763.1| (AB017109) HacB [Thermus thermophilus] 135 3e-31
sp|P31960|LEUD_CLOPA 3-ISOPROPYLMALATE DEHYDRATASE SMALL SUBUNIT... 115 2e-25
pir||H75373 3-isopropylmalate dehydratase, small subunit - Deino... 112 3e-24
gb|AAC64298.1| (AC004450) 3-isopropylmalate dehydratase, small s... 111 4e-24
sp|Q92412|LYS4_EMENI HOMOACONITASE PRECURSOR (HOMOACONITATE HYDR... 104 6e-22
gb|AAC64299.1| (AC004450) 3-isopropylmalate dehydratase, small s... 104 8e-22
emb|CAA89720.1| (Z49701) unknown [Saccharomyces cerevisiae] 99 3e-20
gi|6320440 homoaconitase; Lys4p [Saccharomyces cerevisiae] >gi|1... 99 3e-20
pir||T47781 3-isopropylmalate dehydratase-like protein (small su... 97 1e-19
pir||T38665 probable homoaconitate hydratase (EC 4.2.1.36) - fis... 88 5e-17
pir||F70453 aconitase - Aquifex aeolicus >gi|2984078|gb|AAC07617... 86 2e-16
sp|P74207|LEUD_SYNY3 3-ISOPROPYLMALATE DEHYDRATASE SMALL SUBUNIT... 81 7e-15
pir||A82071 3-isopropylmalate dehydratase, small chain VC2493 [i... 80 1e-14
sp|Q02144|LEUD_LACLA 3-ISOPROPYLMALATE DEHYDRATASE SMALL SUBUNIT... 80 2e-14
gb|AAG20620.1| (AE005132) aconitase; Can [Halobacterium sp. NRC-1] 79 3e-14
sp|Q9ZND4|LEUD_THETH 3-ISOPROPYLMALATE DEHYDRATASE SMALL SUBUNIT... 78 4e-14
sp|P55811|LEU2_RHINI 3-ISOPROPYLMALATE DEHYDRATASE (ISOPROPYLMAL... 77 1e-13
sp|P18250|LEU2_PHYBL 3-ISOPROPYLMALATE DEHYDRATASE (ISOPROPYLMAL... 76 2e-13
dbj|BAB06774.1| (AP001517) 3-isopropylmalate dehydratase small s... 76 2e-13
sp|Q00464|LEU2_CANMA 3-ISOPROPYLMALATE DEHYDRATASE (ISOPROPYLMAL... 76 3e-13
pir||S26864 3-isopropylmalate dehydratase (EC 4.2.1.33) - Phycom... 75 4e-13
pir||H81269 probable 3-isopropylmalate dehydratase (EC 4.2.1.33)... 75 7e-13
gb|AAB19612.1| (S57886) isopropylmalate isomerase {EC 4.2.1.33} ... 74 1e-12
gi|6321429 isopropylmalate isomerase; Leu1p [Saccharomyces cerev... 74 1e-12
emb|CAB99455.1| (AJ278693) 3-isopropylmalate dehydratase [Yarrow... 74 1e-12
sp|O14289|LEU2_SCHPO 3-ISOPROPYLMALATE DEHYDRATASE (ISOPROPYLMAL... 73 1e-12
sp|P04787|LEUD_SALTY 3-ISOPROPYLMALATE DEHYDRATASE SMALL SUBUNIT... 73 2e-12
sp|P30126|LEUD_ECOLI 3-ISOPROPYLMALATE DEHYDRATASE SMALL SUBUNIT... 72 4e-12
sp|P55251|LEU2_RHIPU 3-ISOPROPYLMALATE DEHYDRATASE (ISOPROPYLMAL... 71 6e-12
sp|P94568|LEUD_BACSU 3-ISOPROPYLMALATE DEHYDRATASE SMALL SUBUNIT... 70 1e-11
sp|P49601|LEU2_USTMA 3-ISOPROPYLMALATE DEHYDRATASE (ISOPROPYLMAL... 70 2e-11
sp|P44438|LEUD_HAEIN 3-ISOPROPYLMALATE DEHYDRATASE SMALL SUBUNIT... 69 3e-11
pir||E81128 3-isopropylmalate dehydratase, small chain NMB1034 [... 69 3e-11
sp|Q9ZEZ5|LEUD_BUCPP 3-ISOPROPYLMALATE DEHYDRATASE SMALL SUBUNIT... 69 4e-11
pir||C81836 probable 3-isopropylmalate dehydratase (EC 4.2.1.33)... 69 4e-11
pir||F83255 3-isopropylmalate dehydratase small subunit PA3120 [... 68 6e-11
gi|10954453 isopropylmalate isomerase subunit [Buchnera aphidico... 68 8e-11
>pir||C75045 3-isopropylmalate dehydratase, small chain (leud-1) PAB0892 -
Pyrococcus abyssi (strain Orsay)
>gi|5458769|emb|CAB50256.1| (AJ248287) 3-isopropylmalate
dehydratase, small subunit (leuD-1) [Pyrococcus abyssi]
Length = 164
Score = 335 bits (850), Expect = 2e-91
Identities = 164/164 (100%), Positives = 164/164 (100%)
Query: 1 MRVRGRAWKYGDNIDTDVIIPARYLNTSDPKELAKHVLEDLDPEFRSKMKPGDIIVAGEN 60
MRVRGRAWKYGDNIDTDVIIPARYLNTSDPKELAKHVLEDLDPEFRSKMKPGDIIVAGEN
Sbjct: 1 MRVRGRAWKYGDNIDTDVIIPARYLNTSDPKELAKHVLEDLDPEFRSKMKPGDIIVAGEN 60
Query: 61 FGCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIGLPILEAPQAVDRIETGDELEV 120
FGCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIGLPILEAPQAVDRIETGDELEV
Sbjct: 61 FGCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIGLPILEAPQAVDRIETGDELEV 120
Query: 121 DFSSGEIRNLTKGEVYRANPFPDFIMEIIKAGGLVEWAKRRLKG 164
DFSSGEIRNLTKGEVYRANPFPDFIMEIIKAGGLVEWAKRRLKG
Sbjct: 121 DFSSGEIRNLTKGEVYRANPFPDFIMEIIKAGGLVEWAKRRLKG 164
>pir||E70421 3-isopropylmalate dehydratase - Aquifex aeolicus
>gi|2983802|gb|AAC07359.1| (AE000738) 3-isopropylmalate
dehydratase [Aquifex aeolicus]
Length = 219
Score = 228 bits (574), Expect = 4e-59
Identities = 111/163 (68%), Positives = 133/163 (81%), Gaps = 1/163 (0%)
Query: 1 MRVRGRAWKYGDNIDTDVIIPARYLNTSDPKELAKHVLEDLD-PEFRSKMKPGDIIVAGE 59
M+ RGR WK+GDN+DTD IIPARYLNTSDP ELAKHV+ED + PEF + K GDIIVAG+
Sbjct: 54 MKFRGRVWKFGDNVDTDQIIPARYLNTSDPYELAKHVMEDSEHPEFAKEHKEGDIIVAGK 113
Query: 60 NFGCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIGLPILEAPQAVDRIETGDELE 119
NFG GSSREHAP+AIK +GV VIAKSFARIF+RNAINIGLPI+EAP+AVD IE GDE+E
Sbjct: 114 NFGSGSSREHAPIAIKYSGVPVVIAKSFARIFFRNAINIGLPIVEAPEAVDEIEHGDEIE 173
Query: 120 VDFSSGEIRNLTKGEVYRANPFPDFIMEIIKAGGLVEWAKRRL 162
VD G I+NL G+ Y+A FP + +I+KAGGL+ +AK +L
Sbjct: 174 VDLEKGVIKNLRTGKEYQATKFPKELQDILKAGGLMAYAKEKL 216
>sp|O67399|LEUD_AQUAE 3-ISOPROPYLMALATE DEHYDRATASE SMALL SUBUNIT (ISOPROPYLMALATE
ISOMERASE) (ALPHA-IPM ISOMERASE) (IPMI)
Length = 168
Score = 228 bits (574), Expect = 4e-59
Identities = 111/163 (68%), Positives = 133/163 (81%), Gaps = 1/163 (0%)
Query: 1 MRVRGRAWKYGDNIDTDVIIPARYLNTSDPKELAKHVLEDLD-PEFRSKMKPGDIIVAGE 59
M+ RGR WK+GDN+DTD IIPARYLNTSDP ELAKHV+ED + PEF + K GDIIVAG+
Sbjct: 3 MKFRGRVWKFGDNVDTDQIIPARYLNTSDPYELAKHVMEDSEHPEFAKEHKEGDIIVAGK 62
Query: 60 NFGCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIGLPILEAPQAVDRIETGDELE 119
NFG GSSREHAP+AIK +GV VIAKSFARIF+RNAINIGLPI+EAP+AVD IE GDE+E
Sbjct: 63 NFGSGSSREHAPIAIKYSGVPVVIAKSFARIFFRNAINIGLPIVEAPEAVDEIEHGDEIE 122
Query: 120 VDFSSGEIRNLTKGEVYRANPFPDFIMEIIKAGGLVEWAKRRL 162
VD G I+NL G+ Y+A FP + +I+KAGGL+ +AK +L
Sbjct: 123 VDLEKGVIKNLRTGKEYQATKFPKELQDILKAGGLMAYAKEKL 165
>gi|11498237 3-isopropylmalate dehydratase, small subunit (leuD-1)
[Archaeoglobus fulgidus]
>gi|3122336|sp|O29626|LE23_ARCFU PUTATIVE
3-ISOPROPYLMALATE DEHYDRATASE SMALL SUBUNIT
(ISOPROPYLMALATE ISOMERASE) (ALPHA-IPM ISOMERASE) (IPMI)
>gi|7482880|pir||E69328 3-isopropylmalate dehydratase,
small subunit (leuD-1) homolog - Archaeoglobus fulgidus
>gi|2649990|gb|AAB90610.1| (AE001061) 3-isopropylmalate
dehydratase, small subunit (leuD-1) [Archaeoglobus
fulgidus]
Length = 161
Score = 215 bits (543), Expect = 2e-55
Identities = 103/155 (66%), Positives = 125/155 (80%), Gaps = 1/155 (0%)
Query: 5 GRAWKYGDNIDTDVIIPARYLNTSDPKELAKHVLEDLDPEFRSKMKPGDIIVAGENFGCG 64
GRAWK+GD+IDTDVII +YL ++P+ELAKHV E+L PEF ++K GD +VAGENFGCG
Sbjct: 2 GRAWKFGDDIDTDVIIQGKYLVINEPEELAKHVFENLRPEFAKEVKKGDFVVAGENFGCG 61
Query: 65 SSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIGLPILEAPQAVDRIETGDELEVDFSS 124
SSREHAPLA+KA G+ VIAKS+ARIF+RNAINIGL +LE + D+IE GDELEVD+
Sbjct: 62 SSREHAPLALKATGIEAVIAKSYARIFFRNAINIGLRVLECKE-TDKIEDGDELEVDYEK 120
Query: 125 GEIRNLTKGEVYRANPFPDFIMEIIKAGGLVEWAK 159
G I N TKGE Y NP PDF+ EI++ GGLVE+AK
Sbjct: 121 GVIYNKTKGEEYPINPLPDFLKEILEKGGLVEFAK 155
>sp|Q58673|LE24_METJA PUTATIVE 3-ISOPROPYLMALATE DEHYDRATASE SMALL SUBUNIT
(ISOPROPYLMALATE ISOMERASE) (ALPHA-IPM ISOMERASE) (IPMI)
>gi|2127721|pir||D64459 3-isopropylmalate dehydratase
(EC 4.2.1.33) - Methanococcus jannaschii
>gi|1591913|gb|AAB99283.1| (U67568) 3-isopropylmalate
dehydratase (leuD) [Methanococcus jannaschii]
Length = 168
Score = 215 bits (541), Expect = 3e-55
Identities = 94/160 (58%), Positives = 129/160 (79%)
Query: 3 VRGRAWKYGDNIDTDVIIPARYLNTSDPKELAKHVLEDLDPEFRSKMKPGDIIVAGENFG 62
++GR WK+G+N+DTD I+PARYL + P+ELA+ V+ DP+F K+KPGDIIV G+NFG
Sbjct: 5 IKGRVWKFGNNVDTDAILPARYLVYTKPEELAQFVMTGADPDFPKKVKPGDIIVGGKNFG 64
Query: 63 CGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIGLPILEAPQAVDRIETGDELEVDF 122
CGSSREHAPL +K AG+SCVIA+SFARIFYRNAIN+GLP++E +++ GDELEV+
Sbjct: 65 CGSSREHAPLGLKGAGISCVIAESFARIFYRNAINVGLPLIECKGISEKVNEGDELEVNL 124
Query: 123 SSGEIRNLTKGEVYRANPFPDFIMEIIKAGGLVEWAKRRL 162
+GEI+NLT GEV + P+F+MEI++AGGL+ + K+++
Sbjct: 125 ETGEIKNLTTGEVLKGQKLPEFMMEILEAGGLMPYLKKKM 164
>sp|Q9WZ25|LEUD_THEMA 3-ISOPROPYLMALATE DEHYDRATASE SMALL SUBUNIT (ISOPROPYLMALATE
ISOMERASE) (ALPHA-IPM ISOMERASE) (IPMI)
>gi|7462039|pir||A72363 3-isopropylmalate dehydratase,
small subunit - Thermotoga maritima (strain MSB8)
>gi|4981070|gb|AAD35640.1|AE001730_8 (AE001730)
3-isopropylmalate dehydratase, small subunit [Thermotoga
maritima]
Length = 166
Score = 209 bits (526), Expect = 2e-53
Identities = 102/164 (62%), Positives = 133/164 (80%), Gaps = 4/164 (2%)
Query: 1 MRVRGRAWKYGDNIDTDVIIPARYLNTSDPKELAKHVLEDLDPEF--RSKMKPGDIIVAG 58
++++G+ + +GDN++TD IIPARYLNTSDP+ELAK+ +ED P F R +K G IIVAG
Sbjct: 3 VKIKGKVFVFGDNVNTDEIIPARYLNTSDPQELAKYCMEDARPGFGRRDDIK-GSIIVAG 61
Query: 59 ENFGCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIGLPILEAPQAVDRIETGDEL 118
ENFGCGSSREHAP+AIKAAG+SCVIAKSFARIF+RNAINIGLPI+E +A D E GD
Sbjct: 62 ENFGCGSSREHAPVAIKAAGISCVIAKSFARIFFRNAINIGLPIVELKEA-DEFEEGDIA 120
Query: 119 EVDFSSGEIRNLTKGEVYRANPFPDFIMEIIKAGGLVEWAKRRL 162
EVD +G +RNLTKG+ YR P+P+F+M+I++AGG +E+ + +
Sbjct: 121 EVDLENGVVRNLTKGKEYRIRPYPEFLMKIMEAGGWLEYCLKEV 164
>sp|O27440|LE24_METTH PUTATIVE 3-ISOPROPYLMALATE DEHYDRATASE SMALL SUBUNIT
(ISOPROPYLMALATE ISOMERASE) (ALPHA-IPM ISOMERASE) (IPMI)
>gi|7482020|pir||E69051 3-isopropylmalate dehydratase,
LeuC subunit - Methanobacterium thermoautotrophicum
(strain Delta H) >gi|2622497|gb|AAB85864.1| (AE000901)
3-isopropylmalate dehydratase, LeuC subunit
[Methanobacterium thermoautotrophicum]
Length = 162
Score = 198 bits (499), Expect = 3e-50
Identities = 89/159 (55%), Positives = 124/159 (77%), Gaps = 2/159 (1%)
Query: 3 VRGRAWKYGDNIDTDVIIPARYLNTSDPKELAKHVLEDLDPEFRSKMKPGDIIVAGENFG 62
++G+ WK+ D++DTD+IIP RYL DP++L +HV+E LDPEF SK+KPGD IVAG+NFG
Sbjct: 1 MKGKVWKFPDDVDTDIIIPGRYLVMRDPEKLREHVMEGLDPEFPSKVKPGDFIVAGKNFG 60
Query: 63 CGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIGLPILEAPQAVDRIETGDELEVDF 122
CGSSREHAPLA+K AG++ VIA+SFARIFYRNAIN+G+P+LEAP +++ GDE+EVD
Sbjct: 61 CGSSREHAPLALKGAGIAAVIAESFARIFYRNAINVGIPLLEAPGITEKLNEGDEIEVDL 120
Query: 123 SSGEIRNLTKGEVYRANPFPDFIMEIIKAGGLVEWAKRR 161
G I + + + PDF++EI++ GGL+ + K++
Sbjct: 121 DRGVI--IRGDDEFPFKKLPDFMVEILEKGGLIPYLKKK 157
>gi|11499350 3-isopropylmalate dehydratase, small subunit (leuD-2)
[Archaeoglobus fulgidus]
>gi|3122335|sp|O28513|LE24_ARCFU PUTATIVE
3-ISOPROPYLMALATE DEHYDRATASE SMALL SUBUNIT
(ISOPROPYLMALATE ISOMERASE) (ALPHA-IPM ISOMERASE) (IPMI)
>gi|7482881|pir||H69469 3-isopropylmalate dehydratase,
small subunit (leuD-2) homolog - Archaeoglobus fulgidus
>gi|2648789|gb|AAB89489.1| (AE000981) 3-isopropylmalate
dehydratase, small subunit (leuD-2) [Archaeoglobus
fulgidus]
Length = 165
Score = 194 bits (488), Expect = 5e-49
Identities = 97/161 (60%), Positives = 120/161 (74%), Gaps = 3/161 (1%)
Query: 1 MRVRGRAWKYGDNIDTDVIIPARYLNT-SDPKELAKHVLEDLDPEFRSKMKPGDIIVAGE 59
M++ GRAWK+GD+I TD I P RY + S+ ELAKHV+ED DP+F K +PGD IVAG+
Sbjct: 1 MKMVGRAWKFGDDISTDHITPGRYYHLRSNMPELAKHVMEDADPDFMKKFRPGDFIVAGK 60
Query: 60 NFGCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIGLPILEAPQAVDRIETGDELE 119
NFG GSSREHAPLA+K AGVS VIAKSFARIFYRNAIN+GLP+L A D I++GDELE
Sbjct: 61 NFGMGSSREHAPLALKIAGVSAVIAKSFARIFYRNAINVGLPVLIAD--TDSIDSGDELE 118
Query: 120 VDFSSGEIRNLTKGEVYRANPFPDFIMEIIKAGGLVEWAKR 160
VD G + N TKG R P P+ +++I+ GGLV + K+
Sbjct: 119 VDLGKGLVVNRTKGIEIRVKPIPEVMLKILHEGGLVSYVKK 159
>pir||D72394 hypothetical protein TM0292 - Thermotoga maritima (strain MSB8)
>gi|4980791|gb|AAD35380.1|AE001711_3 (AE001711)
3-isopropylmalate dehydratase, small subunit, putative
[Thermotoga maritima]
Length = 166
Score = 194 bits (487), Expect = 7e-49
Identities = 93/159 (58%), Positives = 120/159 (74%), Gaps = 2/159 (1%)
Query: 3 VRGRAWKYGDNIDTDVIIPARYLNT-SDPKELAKHVLEDLDPEFRSKMKPGDIIVAGENF 61
+RGR WK+GDNI TD I P RY + ++ +ELAKHVLED +F K++ GDIIVAG+NF
Sbjct: 2 IRGRVWKFGDNISTDHIAPGRYFHLRNNLEELAKHVLEDAMEDFAKKVQKGDIIVAGKNF 61
Query: 62 GCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIGLPILEAPQAVDRIETGDELEVD 121
G GSSREHA IK AGVSC++AKSFARIFYRNAIN+GLP++E + VD I GDELE+D
Sbjct: 62 GLGSSREHAARIIKIAGVSCIVAKSFARIFYRNAINVGLPVIELKE-VDEINQGDELEID 120
Query: 122 FSSGEIRNLTKGEVYRANPFPDFIMEIIKAGGLVEWAKR 160
+G ++NLT G+ YR P P F++EI+K G+V + K+
Sbjct: 121 LENGVLKNLTTGKEYRFTPIPKFLLEILKEDGIVNYLKK 159
>sp|O26917|LE23_METTH PUTATIVE 3-ISOPROPYLMALATE DEHYDRATASE SMALL SUBUNIT
(ISOPROPYLMALATE ISOMERASE) (ALPHA-IPM ISOMERASE) (IPMI)
>gi|7482021|pir||E69210 3-isopropylmalate dehydratase,
LeuD subunit - Methanobacterium thermoautotrophicum
(strain Delta H) >gi|2621919|gb|AAB85327.1| (AE000860)
3-isopropylmalate dehydratase, LeuD subunit
[Methanobacterium thermoautotrophicum]
Length = 170
Score = 193 bits (485), Expect = 1e-48
Identities = 92/153 (60%), Positives = 115/153 (75%), Gaps = 3/153 (1%)
Query: 3 VRGRAWKYGDNIDTDVIIPARYLNTSDPKELAKHVLEDLDPEFRSKMKPGDIIVAGENFG 62
+RGR W++GDN+DTD+IIP RYL T ELA HV+E PEF S+++ GDIIVAG NFG
Sbjct: 5 IRGRVWRFGDNVDTDMIIPGRYLRTFSLDELASHVMEGARPEFASQVRKGDIIVAGRNFG 64
Query: 63 CGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIGLPILEAPQAVDRIETGDELEVDF 122
CGSSRE AP+A+K AGV +IA+SFARIFYRNAINIGLP++ A D GDE+ +D
Sbjct: 65 CGSSREQAPVALKHAGVVAIIAESFARIFYRNAINIGLPVIMAKVDAD---DGDEVSIDL 121
Query: 123 SSGEIRNLTKGEVYRANPFPDFIMEIIKAGGLV 155
SG+IRNLT G YR PF D+++ I++ GGLV
Sbjct: 122 RSGQIRNLTAGSEYRMKPFNDYMLSILEDGGLV 154
>pir||A75160 3-isopropylmalate dehydratase, small chain (leud-2) PAB0288 -
Pyrococcus abyssi (strain Orsay)
>gi|5457870|emb|CAB49360.1| (AJ248284) 3-isopropylmalate
dehydratase, small subunit (leuD-2) [Pyrococcus abyssi]
Length = 163
Score = 166 bits (415), Expect = 2e-40
Identities = 79/161 (49%), Positives = 112/161 (69%), Gaps = 4/161 (2%)
Query: 1 MRVRGRAWKYGDNIDTDVIIPARYLNTSDPKELAKHVLEDLDPEFRSKMKPGDIIVAGEN 60
M GR WK+ DN+ TD I P RY T DP+ELA+ ++ PEF K++ GD++V G+N
Sbjct: 1 MITTGRVWKFWDNVSTDEITPGRYNLTKDPQELARIAFIEVRPEFAEKVRRGDVVVGGKN 60
Query: 61 FGCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIGLPILEAPQAVDRIETGDELEV 120
FG GSSRE A LA+KAAGVS +IAKSF RIFYRNA+N+G+P+L D +E GD + V
Sbjct: 61 FGIGSSRESAALALKAAGVSGIIAKSFGRIFYRNAVNLGIPLLIGD--TDELEDGDVITV 118
Query: 121 DFSSGEIRNLTKGEVYRANPFPDFIMEIIKAGGLVEWAKRR 161
++ +GE+R G+ + P P F++EI++ GG++E+ +RR
Sbjct: 119 NWETGEVRK--NGQTLQFEPLPGFLLEIVREGGILEFIRRR 157
>sp|Q58667|LE23_METJA PUTATIVE 3-ISOPROPYLMALATE DEHYDRATASE SMALL SUBUNIT
(ISOPROPYLMALATE ISOMERASE) (ALPHA-IPM ISOMERASE) (IPMI)
>gi|2127722|pir||F64458 3-isopropylmalate dehydratase
(EC 4.2.1.33) - Methanococcus jannaschii
>gi|1591907|gb|AAB99277.1| (U67568) 3-isopropylmalate
dehydratase (leuD) [Methanococcus jannaschii]
Length = 170
Score = 163 bits (408), Expect = 1e-39
Identities = 85/162 (52%), Positives = 107/162 (65%), Gaps = 4/162 (2%)
Query: 1 MRVRGRAWKYGDNIDTDVIIPARYLNTSDPKELAKHVLEDLDPEFRSKMKPGDIIVAGEN 60
M ++GRA K+GD++DTD IIP YL T+DP ELA H + +D F K+K GD+IVAGEN
Sbjct: 1 MIIKGRAHKFGDDVDTDAIIPGPYLRTTDPYELASHCMAGIDENFPKKVKEGDVIVAGEN 60
Query: 61 FGCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIGL-PILEAPQAVDRIETGDELE 119
FGCGSSRE A +AIK G+ VIAKSFARIFYRNAIN+GL PI+ D I+ GD +E
Sbjct: 61 FGCGSSREQAVIAIKYCGIKAVIAKSFARIFYRNAINVGLIPII---ANTDEIKDGDIVE 117
Query: 120 VDFSSGEIRNLTKGEVYRANPFPDFIMEIIKAGGLVEWAKRR 161
+D EI K + + EI+ AGGLV + K+R
Sbjct: 118 IDLDKEEIVITNKNKTIKCETPKGLEREILAAGGLVNYLKKR 159
>gb|AAK42607.1| 3-isopropylmalate dehydratase, small subunit (isopropylmalate
isomerase) (alpha IPM isomerase) (IPMI) (leuD)
[Sulfolobus solfataricus]
Length = 165
Score = 162 bits (406), Expect = 2e-39
Identities = 81/160 (50%), Positives = 110/160 (68%), Gaps = 2/160 (1%)
Query: 1 MRVRGRAWKYGDNIDTDVIIPARYLNTSDPKELAKHVLEDLDPEFRSKMKPGDIIVAGEN 60
M + G K+GD IDTD+IIPARYL +DP+ LA+HV+E LDPEF K G IIVAG+
Sbjct: 1 MIIEGPVIKFGDKIDTDIIIPARYLKYTDPQYLAQHVMEPLDPEFYKKASKGVIIVAGKV 60
Query: 61 FGCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIGLPILEAPQAVDRIETGDELEV 120
FG GSSRE A +A+KAAGV V+A+SFARIFYRNAIN GLP++ P + I+ +++
Sbjct: 61 FGMGSSREQAAIALKAAGVKAVVAESFARIFYRNAINNGLPVITLPNSTKEIDENSYVKI 120
Query: 121 DFSSGEIRNLTKGEVYRANPFPDFIMEIIKAGGLVEWAKR 160
D +GEI L +V + +EI++AGG++E+ K+
Sbjct: 121 DVETGEI--LVGNKVLKGKGITGMALEILQAGGIMEYLKK 158
>sp|O59393|LEUD_PYRHO PUTATIVE 3-ISOPROPYLMALATE DEHYDRATASE SMALL SUBUNIT
(ISOPROPYLMALATE ISOMERASE) (ALPHA-IPM ISOMERASE) (IPMI)
>gi|7520855|pir||G71180 probable 3-isopropylmalate
dehydratase - Pyrococcus horikoshii
>gi|3258155|dbj|BAA30838.1| (AP000007) 163aa long
hypothetical 3-isopropylmalate dehydratase [Pyrococcus
horikoshii]
Length = 163
Score = 161 bits (402), Expect = 6e-39
Identities = 80/162 (49%), Positives = 114/162 (69%), Gaps = 6/162 (3%)
Query: 1 MRVRGRAWKYGDNIDTDVIIPARYLNTSDPKELAKHVLEDLDPEFRSKMKPGDIIVAGEN 60
M G+ WK+GD+I TD I P RY T DPKELAK ++ P+F ++PGD++VAG+N
Sbjct: 1 MITTGKVWKFGDDISTDEITPGRYNLTKDPKELAKIAFIEVRPDFARNVRPGDVVVAGKN 60
Query: 61 FGCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIGLPILEAPQAVDRIETGDELEV 120
FG GSSRE A LA+KA G++ VIA+SF RIFYRNAINIG+P+L + ++ GD + V
Sbjct: 61 FGIGSSRESAALALKALGIAGVIAESFGRIFYRNAINIGIPLLLG--KTEGLKDGDLVTV 118
Query: 121 DFSSGEIRNLTKG-EVYRANPFPDFIMEIIKAGGLVEWAKRR 161
++ +GE+R KG E+ P DF++EI++ GG++E+ +RR
Sbjct: 119 NWETGEVR---KGDEILMFEPLEDFLLEIVREGGILEYIRRR 157
>pir||F75355 3-isopropylmalate dehydratase, small subunit - Deinococcus
radiodurans (strain R1)
>gi|6459552|gb|AAF11332.1|AE002019_5 (AE002019)
3-isopropylmalate dehydratase, small subunit
[Deinococcus radiodurans]
Length = 208
Score = 150 bits (375), Expect = 9e-36
Identities = 75/148 (50%), Positives = 100/148 (66%)
Query: 12 DNIDTDVIIPARYLNTSDPKELAKHVLEDLDPEFRSKMKPGDIIVAGENFGCGSSREHAP 71
D+I+TD IIPAR+L T ELAK+ +ED D +F +++PGDIIVAG +FGCGSSREHA
Sbjct: 10 DHINTDEIIPARHLTTDVESELAKYAMEDYDKDFVRRVQPGDIIVAGADFGCGSSREHAV 69
Query: 72 LAIKAAGVSCVIAKSFARIFYRNAINIGLPILEAPQAVDRIETGDELEVDFSSGEIRNLT 131
A++ AGVS VIA +FARI+YRN+IN G LE + + G+E E+D G IRN
Sbjct: 70 WALRGAGVSAVIAPNFARIYYRNSINNGFLALECEGITELFQDGEEAELDLKGGTIRNPR 129
Query: 132 KGEVYRANPFPDFIMEIIKAGGLVEWAK 159
G+ P P F +++ KAGG +E+ K
Sbjct: 130 TGKELSFVPVPQFALDVQKAGGWLEYMK 157
>dbj|BAA74763.1| (AB017109) HacB [Thermus thermophilus]
Length = 163
Score = 135 bits (337), Expect = 3e-31
Identities = 69/157 (43%), Positives = 102/157 (64%), Gaps = 5/157 (3%)
Query: 6 RAWKYGDNIDTDVIIPARYLNTSDPKE-LAKHVLEDLDPEFRSKMKPGDIIVAGENFGCG 64
R WK+GD I+TD I+P +Y ++ + L PEF +++PGDI+V G N G G
Sbjct: 3 RVWKFGDQINTDDILPGKYAPFMVGEDRFHLYAFAHLRPEFAKEVRPGDILVFGRNAGLG 62
Query: 65 SSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIGLPILEAPQAVDRIETGDELEVDFSS 124
SSRE+AP A+K GV +IAKS+ARIF+RN +N+G+ E+ + VD +E GDE+E+D S
Sbjct: 63 SSREYAPEALKRLGVRAIIAKSYARIFFRNLVNLGIVPFESEEVVDALEDGDEVELDLES 122
Query: 125 GEIRNLTKGEV-YRANPFPDFIMEIIKAGGLVEWAKR 160
G LT+GE + P P F++E +K G L+++ K+
Sbjct: 123 GV---LTRGEERFALRPPPPFLLEALKEGSLLDYYKK 156
>sp|P31960|LEUD_CLOPA 3-ISOPROPYLMALATE DEHYDRATASE SMALL SUBUNIT (ISOPROPYLMALATE
ISOMERASE) (ALPHA-IPM ISOMERASE) (IPMI)
>gi|144841|gb|AAC41393.1| (L06666) isopropylmalate
isomerase [Clostridium pasteurianum]
Length = 100
Score = 115 bits (286), Expect = 2e-25
Identities = 54/91 (59%), Positives = 72/91 (78%)
Query: 69 HAPLAIKAAGVSCVIAKSFARIFYRNAINIGLPILEAPQAVDRIETGDELEVDFSSGEIR 128
HAP+A+KAAGVSCVIAKSFARIFYRN+INIG PILE +AV+ + ELEVDF++G I+
Sbjct: 1 HAPIALKAAGVSCVIAKSFARIFYRNSINIGFPILECEEAVNDAKNNHELEVDFTTGIIK 60
Query: 129 NLTKGEVYRANPFPDFIMEIIKAGGLVEWAK 159
N+T G+ Y+A +P F+++I+K GL+ K
Sbjct: 61 NITLGKEYKAQAYPQFMIDIMKNEGLINCVK 91
>pir||H75373 3-isopropylmalate dehydratase, small subunit - Deinococcus
radiodurans (strain R1)
>gi|6459381|gb|AAF11175.1|AE002005_4 (AE002005)
3-isopropylmalate dehydratase, small subunit
[Deinococcus radiodurans]
Length = 177
Score = 112 bits (277), Expect = 3e-24
Identities = 56/156 (35%), Positives = 98/156 (61%), Gaps = 4/156 (2%)
Query: 6 RAWKYGDNIDTDVIIPARYLNTSDPKELAK-HVLEDLDPEFRSKMKPGDIIVAGENFGCG 64
R WK+GD+++TD I+P ++ +++ + + PEF ++++PGD+++ G N+G G
Sbjct: 3 RIWKFGDSVNTDDILPGKFAPFMAGEDVFQTFAFHYVRPEFAAQVQPGDVLIGGRNWGLG 62
Query: 65 SSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIGLPILEAPQAVDRIETGDELEVDFSS 124
SSRE+AP A+K + ++A SFARI YRN +N+G+P E + +E GDE+ +D +
Sbjct: 63 SSREYAPQALKKLHIGGIVAPSFARIHYRNLLNLGIPAFEY-DLTELLEDGDEVTLDAQT 121
Query: 125 GEIRNLTKGEVYRANPFPDFIMEIIKAGGLVEWAKR 160
G + G V + P P+F+ E +K G ++E+ K+
Sbjct: 122 G-LLTYADGTV-QLPPPPEFLREALKEGSILEFFKK 155
>gb|AAC64298.1| (AC004450) 3-isopropylmalate dehydratase, small subunit
[Arabidopsis thaliana]
Length = 251
Score = 111 bits (276), Expect = 4e-24
Identities = 68/172 (39%), Positives = 100/172 (57%), Gaps = 17/172 (9%)
Query: 5 GRAWKYGDNIDTDVIIPARYLNT--SDPKE---LAKHVLEDLDPEFRSK-MKPGD----- 53
G + GDNIDTD IIPA +L S+P+E L + L L ++ + ++PG+
Sbjct: 72 GLCYVVGDNIDTDQIIPAEFLTLVPSNPEEYEKLGSYALVGLPASYKERFVQPGEMKTKY 131
Query: 54 -IIVAGENFGCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIG--LPILEAPQAVD 110
II+ GENFGCGSSREHAP+ + AAG V+A+S+ARIF+RN++ G P+ + D
Sbjct: 132 SIIIGGENFGCGSSREHAPVCLGAAGAKAVVAQSYARIFFRNSVATGEVYPLDSEVRVCD 191
Query: 111 RIETGDELEVDFSSGE--IRNLTKGEVYRANPFPDFIMEIIKAGGLVEWAKR 160
TGD V+ G+ + N T G+ Y+ P D +I AGG+ +A++
Sbjct: 192 ECTTGDVATVELREGDSILINHTTGKEYKLKPIGD-AGPVIDAGGIFAYARK 242
>sp|Q92412|LYS4_EMENI HOMOACONITASE PRECURSOR (HOMOACONITATE HYDRATASE)
>gi|1628374|emb|CAA67943.1| (X99624) homoaconitase
[Aspergillus nidulellus]
Length = 775
Score = 104 bits (257), Expect = 6e-22
Identities = 64/170 (37%), Positives = 93/170 (54%), Gaps = 19/170 (11%)
Query: 12 DNIDTDVIIPARYLNTSD--PKELAKHVLEDLDPEFRSKMKPGDIIVAGENFGCGSSREH 69
DN++TD I P +Y D P+ +A+ +E+ DPEF + K GDI+V+G NFGCGSSRE
Sbjct: 604 DNVNTDGIYPGKYTYQDDVPPETMARVCMENYDPEFSTTAKEGDILVSGFNFGCGSSREQ 663
Query: 70 APLAIKAAGVSCVIAKSFARIFYRNAINIGLPILEAPQAVDRIE----TGDEL------- 118
A AI A + V++ SF IF RN+IN L LE P+ V+R+ +GD++
Sbjct: 664 AATAILAKKIPLVVSGSFGNIFSRNSINNALMGLEVPRLVNRLRETFGSGDKVLTRRTGW 723
Query: 119 ----EVDFSSGEIRNLTKGE--VYRANPFPDFIMEIIKAGGLVEWAKRRL 162
+V S E++ G ++ P + EII GGL +W K +
Sbjct: 724 TLTWDVRKSQIEVQEGPGGPKWTHKVGELPPNVQEIIAKGGLEKWVKNAI 773
>gb|AAC64299.1| (AC004450) 3-isopropylmalate dehydratase, small subunit
[Arabidopsis thaliana]
Length = 256
Score = 104 bits (256), Expect = 8e-22
Identities = 66/172 (38%), Positives = 96/172 (55%), Gaps = 19/172 (11%)
Query: 5 GRAWKYGDNIDTDVIIPARYL-----NTSDPKELAKHVLEDLDPEFRSK--MKPGD---- 53
G + DNIDTD IIPA N + E+A H L L P+F ++PG+
Sbjct: 78 GLCYVLKDNIDTDQIIPAGAACTFPSNQQERDEIAAHALSGL-PDFHKTRFIEPGENRSK 136
Query: 54 --IIVAGENFGCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIG--LPILEAPQAV 109
II+ GENFGCGSSREHAP+ + AAG ++A+S+ARIF+RN++ G P+ +
Sbjct: 137 YSIIIGGENFGCGSSREHAPVCLGAAGAKAIVAESYARIFFRNSVATGEVFPLESEVRVC 196
Query: 110 DRIETGD--ELEVDFSSGEIRNLTKGEVYRANPFPDFIMEIIKAGGLVEWAK 159
+ +TGD +E+ S G + N T G+ Y+ D +I AGG+ +A+
Sbjct: 197 EECKTGDTVTIELSDSGGLLTNHTTGKNYKLKSIGD-AGPVIDAGGIFAYAR 247
>emb|CAA89720.1| (Z49701) unknown [Saccharomyces cerevisiae]
Length = 375
Score = 98.7 bits (242), Expect = 3e-20
Identities = 65/173 (37%), Positives = 94/173 (53%), Gaps = 23/173 (13%)
Query: 12 DNIDTDVIIPARYLNTSD-PKE-LAKHVLEDLDPEFRSKMKPGDIIVAGENFGCGSSREH 69
DNI+TD I P +Y D PKE +A+ +E+ D EFR+K+ PGDI+V+G NFG GSSRE
Sbjct: 204 DNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQ 263
Query: 70 APLAIKAAGVSCVIAKSFARIFYRNAINIGLPILEAPQAVDRI-------------ETGD 116
A A+ A G++ V++ SF IF RN+IN L LE P + ++ TG
Sbjct: 264 AATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGW 323
Query: 117 ELEVDFSSGEIRNLTKGEV-------YRANPFPDFIMEIIKAGGLVEWAKRRL 162
L+ D + ++ +T+G + + + EII GGL W K +L
Sbjct: 324 FLKWDVADAKV-VVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 375
>gi|6320440 homoaconitase; Lys4p [Saccharomyces cerevisiae]
>gi|1346476|sp|P49367|LYS4_YEAST HOMOACONITASE PRECURSOR
(HOMOACONITATE HYDRATASE) >gi|2131287|pir||S61067
homoaconitate hydratase (EC 4.2.1.36) precursor - yeast
(Saccharomyces cerevisiae) >gi|1089840|emb|CAA63764.1|
(X93502) homoaconitase [Saccharomyces cerevisiae]
>gi|1197581|gb|AAA88902.1| (U46154) lysine biosynthesis
enzyme homoaconitase [Saccharomyces cerevisiae]
Length = 693
Score = 98.7 bits (242), Expect = 3e-20
Identities = 65/173 (37%), Positives = 94/173 (53%), Gaps = 23/173 (13%)
Query: 12 DNIDTDVIIPARYLNTSD-PKE-LAKHVLEDLDPEFRSKMKPGDIIVAGENFGCGSSREH 69
DNI+TD I P +Y D PKE +A+ +E+ D EFR+K+ PGDI+V+G NFG GSSRE
Sbjct: 522 DNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQ 581
Query: 70 APLAIKAAGVSCVIAKSFARIFYRNAINIGLPILEAPQAVDRI-------------ETGD 116
A A+ A G++ V++ SF IF RN+IN L LE P + ++ TG
Sbjct: 582 AATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGW 641
Query: 117 ELEVDFSSGEIRNLTKGEV-------YRANPFPDFIMEIIKAGGLVEWAKRRL 162
L+ D + ++ +T+G + + + EII GGL W K +L
Sbjct: 642 FLKWDVADAKV-VVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
>pir||T47781 3-isopropylmalate dehydratase-like protein (small subunit) -
Arabidopsis thaliana >gi|7529742|emb|CAB86927.1|
(AL163527) 3-isopropylmalate dehydratase-like protein
(small subunit) [Arabidopsis thaliana]
Length = 253
Score = 96.7 bits (237), Expect = 1e-19
Identities = 62/167 (37%), Positives = 93/167 (55%), Gaps = 20/167 (11%)
Query: 12 DNIDTDVIIPARYLNT-----SDPKELAKHVLEDLDPEFRSK--MKPGD------IIVAG 58
DNIDTD IIPA Y D ++L L L P+F ++ + PG+ +I+ G
Sbjct: 82 DNIDTDQIIPAEYGTLIPSIPEDREKLGSFALNGL-PKFYNERFVVPGEMKSKYSVIIGG 140
Query: 59 ENFGCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIG--LPILEAPQAVDRIETGD 116
+NFGCGSSREHAP+ + AAG V+A+S+ARIF+RN + G P+ + D +TGD
Sbjct: 141 DNFGCGSSREHAPVCLGAAGAKAVVAESYARIFFRNCVATGEIFPLESEVRICDECKTGD 200
Query: 117 ELEVDF---SSGEIRNLTKGEVYRANPFPDFIMEIIKAGGLVEWAKR 160
+ ++ S + N T + Y+ P D +I AGG+ +A++
Sbjct: 201 VVTIEHKEDGSSLLINHTTRKEYKLKPLGD-AGPVIDAGGIFAYARK 246
>pir||T38665 probable homoaconitate hydratase (EC 4.2.1.36) - fission yeast
(Schizosaccharomyces pombe) >gi|5706517|emb|CAB52279.1|
(AL109739) putative homoaconitate hydratase (EC
4.2.1.36) [Schizosaccharomyces pombe]
Length = 721
Score = 88.2 bits (215), Expect = 5e-17
Identities = 57/169 (33%), Positives = 85/169 (49%), Gaps = 18/169 (10%)
Query: 12 DNIDTDVIIPARYLNTSD--PKELAKHVLEDLDPEFRSKMKPGDIIVAGENFGCGSSREH 69
DN++TD I P RY D +E+AK +E+ D EF K K DI+V+G NFG GSSRE
Sbjct: 549 DNLNTDGIYPGRYTYRDDITKEEMAKVCMENYDSEFGKKTKKDDILVSGFNFGTGSSREQ 608
Query: 70 APLAIKAAGVSCVIAKSFARIFYRNAINIGLPILEAPQAVDRIET---GDELEVDFSSG- 125
A AI + G+ V+ SF+ IF RN+IN L ++ P V ++ T + E+ +G
Sbjct: 609 AATAILSRGIPLVVGGSFSDIFKRNSINNALLAIQLPDLVQKLRTAFANESKELTRRTGW 668
Query: 126 ----EIRNLT--------KGEVYRANPFPDFIMEIIKAGGLVEWAKRRL 162
++R T K ++ + + + GGL W K +
Sbjct: 669 HLKWDVRKSTVTVTTSDNKEMSWKIGELGNSVQSLFVRGGLEGWVKHEI 717
>pir||F70453 aconitase - Aquifex aeolicus >gi|2984078|gb|AAC07617.1| (AE000756)
aconitase [Aquifex aeolicus]
Length = 659
Score = 86.2 bits (210), Expect = 2e-16
Identities = 67/173 (38%), Positives = 91/173 (51%), Gaps = 26/173 (15%)
Query: 12 DNIDTDVIIPA--RYLNT-SDPKELAKHVLEDLDPEFRSKMKP------GDIIVAGENFG 62
DNI TD I+PA + L S+ ++++V +DPEF +MK II+ GEN+G
Sbjct: 483 DNITTDHIMPAGAKILPLRSNIYAISEYVYHYVDPEFVPRMKKLKEKGKAGIIIGGENYG 542
Query: 63 CGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIGLPILE--APQAVDRIETGDELEV 120
GSSREHA LA + GV VIAKSFARI + N +N G+ LE + D+ GDE+E+
Sbjct: 543 QGSSREHAALAPRFLGVRAVIAKSFARIHHANLVNFGVVPLEFKNKEDYDKFSLGDEIEI 602
Query: 121 D-----FSSGE---IRNLTKGE----VYRANPFPDFIMEIIKAGGLVEWAKRR 161
GE + N T GE Y P EI+ AGG + + K +
Sbjct: 603 PNLIERLKKGEDILVINKTTGEEILCTYNLTPVQ---KEILIAGGRLNYIKNK 652
>sp|P74207|LEUD_SYNY3 3-ISOPROPYLMALATE DEHYDRATASE SMALL SUBUNIT (ISOPROPYLMALATE
ISOMERASE) (ALPHA-IPM ISOMERASE) (IPMI)
>gi|7437050|pir||S75839 3-isopropylmalate dehydratase
(EC 4.2.1.33) chain leuD - Synechocystis sp. (strain PCC
6803) >gi|1653384|dbj|BAA18298.1| (D90913)
3-isopropylmalate dehydratase [Synechocystis sp.]
Length = 200
Score = 81.1 bits (197), Expect = 7e-15
Identities = 47/113 (41%), Positives = 64/113 (56%), Gaps = 8/113 (7%)
Query: 2 RVRGRAWKY-GDNIDTDVIIPARYLNTSDPKELAKHVLED-------LDPEFRSKMKPGD 53
+++G+A GD+IDTD IIPAR+L L +HV D P S+ +
Sbjct: 6 QIQGKALPLVGDDIDTDRIIPARFLRCVTFDGLGEHVFADDRQQQGGNHPFDLSQYQDAT 65
Query: 54 IIVAGENFGCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIGLPILEAP 106
++V NFGCGSSREHAP AI G+ +I +SFA IF N + G+P + AP
Sbjct: 66 VLVVNRNFGCGSSREHAPQAIIKWGIKAIIGESFAEIFLGNCLANGVPCVTAP 118
>pir||A82071 3-isopropylmalate dehydratase, small chain VC2493 [imported] -
Vibrio cholerae (group O1 strain N16961)
>gi|9657073|gb|AAF95635.1| (AE004318) 3-isopropylmalate
dehydratase, small subunit [Vibrio cholerae]
Length = 200
Score = 80.0 bits (194), Expect = 1e-14
Identities = 47/116 (40%), Positives = 65/116 (55%), Gaps = 14/116 (12%)
Query: 13 NIDTDVIIPARYLNTSDPKELAKHVLED----------LDPEF---RSKMKPGDIIVAGE 59
N+DTD IIP ++L + KH+ D +PEF + + + I++A E
Sbjct: 18 NVDTDAIIPKQFLQKVNRTGFGKHLFHDWRFLDDAGEKANPEFVMNQPRYQDASILLARE 77
Query: 60 NFGCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIGL-PILEAPQAVDRIET 114
NFGCGSSREHAP A+ G+ +IA SFA IFY N+IN + P+ Q VD + T
Sbjct: 78 NFGCGSSREHAPWALADYGIRVMIAPSFADIFYGNSINNQMVPVRLTEQEVDELFT 133
>sp|Q02144|LEUD_LACLA 3-ISOPROPYLMALATE DEHYDRATASE SMALL SUBUNIT (ISOPROPYLMALATE
ISOMERASE) (ALPHA-IPM ISOMERASE) (IPMI)
>gi|1361378|pir||E36889 probable 3-isopropylmalate
dehydratase (EC 4.2.1.33) chain leuD - Lactococcus
lactis subsp. lactis >gi|2565154|gb|AAB81916.1| (U92974)
LeuD [Lactococcus lactis]
Length = 191
Score = 79.6 bits (193), Expect = 2e-14
Identities = 47/125 (37%), Positives = 72/125 (57%), Gaps = 15/125 (12%)
Query: 12 DNIDTDVIIPARYLNTSDPKELAKHV------LEDLD--PEF---RSKMKPGDIIVAGEN 60
DNIDTD IIP ++L D K K++ L+D D P+F K K ++++G+N
Sbjct: 17 DNIDTDQIIPKQFLKAIDKKGFGKNLFYEWRYLKDYDENPDFILNAPKYKKASLLISGDN 76
Query: 61 FGCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIGLPILEAPQAV----DRIETGD 116
FG GSSREHA A+ G +IA S++ IFY NA+ GL ++ P+ V ++ + +
Sbjct: 77 FGSGSSREHAAWALSDYGFRAIIAGSYSDIFYNNALKNGLLPIKQPREVLNQLTKLSSQE 136
Query: 117 ELEVD 121
E+ +D
Sbjct: 137 EITID 141
>gb|AAG20620.1| (AE005132) aconitase; Can [Halobacterium sp. NRC-1]
Length = 661
Score = 79.2 bits (192), Expect = 3e-14
Identities = 54/125 (43%), Positives = 70/125 (55%), Gaps = 7/125 (5%)
Query: 3 VRGRAW-KYGDNIDTDVIIPAR---YLNTSDPKELAKHVLEDLDPEFRSKMKPGD--IIV 56
VRG K DNI TD IIPA S+ + L++ L +D F + K D ++V
Sbjct: 474 VRGETLLKMQDNITTDHIIPATSDILKFRSNIERLSEFTLSRIDDTFAERAKAADSGVLV 533
Query: 57 AGENFGCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIG-LPILEAPQAVDRIETG 115
AGEN+G GSSREHA + GV V+A+SFARI N N G LP+ + RIE G
Sbjct: 534 AGENYGQGSSREHAAMCPMFLGVESVLAQSFARIHKANLFNFGILPLNIDEETYARIEQG 593
Query: 116 DELEV 120
D++EV
Sbjct: 594 DDVEV 598
>sp|Q9ZND4|LEUD_THETH 3-ISOPROPYLMALATE DEHYDRATASE SMALL SUBUNIT (ISOPROPYLMALATE
ISOMERASE) (ALPHA-IPM ISOMERASE) (IPMI)
>gi|4164164|dbj|BAA37139.1| (AB017135) isopropylmalate
isomerase small subunit [Thermus thermophilus]
Length = 201
Score = 78.4 bits (190), Expect = 4e-14
Identities = 54/144 (37%), Positives = 78/144 (53%), Gaps = 18/144 (12%)
Query: 3 VRGRAWKY-GDNIDTDVIIPARYLNTSDPKELAKHVLEDLDPEFRSKMKP---------- 51
+RG+A G++IDTD I+PAR++ + L +++ D + + KP
Sbjct: 8 IRGKAVPLRGEDIDTDRILPARFMKVLTFEGLGQYLFYDERFDEKGNPKPHPLNDPRYRG 67
Query: 52 GDIIVAGENFGCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIGLPILE-APQAVD 110
I++ FG GSSREHAP AIK AG +I +SFA IF+ NA IGLP + AP+ +
Sbjct: 68 ATILLVESGFGSGSSREHAPQAIKRAGFKAIIGESFAEIFFGNATAIGLPCVSLAPEDLG 127
Query: 111 ----RIETGDELEV--DFSSGEIR 128
+E ELEV D + E+R
Sbjct: 128 VLFRSVEENPELEVEIDLVNKEVR 151
>sp|P55811|LEU2_RHINI 3-ISOPROPYLMALATE DEHYDRATASE (ISOPROPYLMALATE ISOMERASE)
(ALPHA-IPM ISOMERASE) (IPMI) >gi|1817566|dbj|BAA09893.1|
(D63833) 3-isopropylmalate dehyratase [Rhizopus niveus]
>gi|1588638|prf||2209244A alpha-isopropylmalate
isomerase [Rhizopus niveus]
Length = 750
Score = 77.3 bits (187), Expect = 1e-13
Identities = 49/135 (36%), Positives = 67/135 (49%), Gaps = 18/135 (13%)
Query: 13 NIDTDVIIPARYLNTSDPKELAKHVLEDL---------DPEF----RSKMKPGDIIVAGE 59
NIDTD+IIP ++L T L + L +P F R+ + ++ G
Sbjct: 542 NIDTDMIIPKQFLKTIKRTGLGSALFYSLRFDPQTGAENPAFVLKERTFRQARILVCTGP 601
Query: 60 NFGCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIGLPILEAPQA-----VDRIET 114
NFGCGSSREHAP A G+ C++A SFA IF+ N G+ + PQA +
Sbjct: 602 NFGCGSSREHAPWAFNDFGIRCILAPSFADIFFNNCFKNGMLPIVLPQAQLEAIAAEAQK 661
Query: 115 GDELEVDFSSGEIRN 129
G E+EVD +RN
Sbjct: 662 GVEVEVDLVQQIVRN 676
>sp|P18250|LEU2_PHYBL 3-ISOPROPYLMALATE DEHYDRATASE (ISOPROPYLMALATE ISOMERASE)
(ALPHA-IPM ISOMERASE) (IPMI)
Length = 744
Score = 76.1 bits (184), Expect = 2e-13
Identities = 57/159 (35%), Positives = 75/159 (46%), Gaps = 29/159 (18%)
Query: 13 NIDTDVIIPARYLNTSDPKELAKHVLEDL----------------DPEFRSKMKPGDIIV 56
N+DTD+IIP ++L T L + L P +RS ++
Sbjct: 533 NVDTDMIIPKQFLKTIKRTGLGSALFYGLRYDPATGAEKPDFVLNQPAYRSSKI---LVC 589
Query: 57 AGENFGCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIG-LPILEAPQAVDRI--- 112
G NFGCGSSREHAP A G+ C+IA SFA IF+ N G LPI+ + + VD +
Sbjct: 590 TGPNFGCGSSREHAPWAFNDFGIRCIIATSFADIFFNNCFKNGMLPIILSQEQVDTLAKY 649
Query: 113 -ETGDELEVDFSSGEIRNLTKGEVYRANPFPDFIMEIIK 150
E+EVD +IR GE+ PF I E K
Sbjct: 650 ATQKAEIEVDLVHQKIR-YPGGEI----PFDXMIEEFRK 683
>dbj|BAB06774.1| (AP001517) 3-isopropylmalate dehydratase small subunit [Bacillus
halodurans]
Length = 194
Score = 76.1 bits (184), Expect = 2e-13
Identities = 49/118 (41%), Positives = 63/118 (52%), Gaps = 13/118 (11%)
Query: 13 NIDTDVIIPARYLNTSDPKELAKHVLEDL--------DPEFRSKM---KPGDIIVAGENF 61
N+DTD IIP ++L + + + D +P+F K G I+VAG NF
Sbjct: 18 NVDTDQIIPKQFLKRVERTGFGQFLFFDWRFLPNGEDNPDFELNQPHAKQGTILVAGHNF 77
Query: 62 GCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIG-LPI-LEAPQAVDRIETGDE 117
GCGSSREHAP AIK G VIA SFA IFY N G LP+ L+ + +E G +
Sbjct: 78 GCGSSREHAPWAIKDYGFRVVIAPSFADIFYNNCFKNGILPVKLKQEEVTALMEKGKD 135
>sp|Q00464|LEU2_CANMA 3-ISOPROPYLMALATE DEHYDRATASE (ISOPROPYLMALATE ISOMERASE)
(ALPHA-IPM ISOMERASE) (IPMI) >gi|1399939|gb|AAB03335.1|
(U60167) alpha isopropylmalate isomerase [Candida
maltosa]
Length = 770
Score = 75.7 bits (183), Expect = 3e-13
Identities = 49/146 (33%), Positives = 73/146 (49%), Gaps = 20/146 (13%)
Query: 10 YGDNIDTDVIIPARYLNTSDPKEL----------AKHVLEDLDPEFRSKMKPGD----II 55
Y N+DTD IIP ++L T L K + +F ++P ++
Sbjct: 554 YKANVDTDAIIPKQFLKTIKRTGLKNGLFYESRFVKMPMVRCQTDFVLNVEPYRQAEILL 613
Query: 56 VAGENFGCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIGLPILEAPQ------AV 109
V G+NFGCGSSREHAP A+K G+ +IA SF IFY N+ L + PQ V
Sbjct: 614 VTGDNFGCGSSREHAPWALKDFGIKSIIAPSFGDIFYNNSFKNFLLPIRIPQDVIESKLV 673
Query: 110 DRIETGDELEVDFSSGEIRNLTKGEV 135
++ G +L +D + +I++ G+V
Sbjct: 674 PVVKAGHKLTIDLPNQQIKDGETGDV 699
>pir||S26864 3-isopropylmalate dehydratase (EC 4.2.1.33) - Phycomyces
blakesleeanus >gi|3113|emb|CAA37257.1| (X53090)
alpha-isopropylmalate isomerase (AA 1-689) [Phycomyces
blakesleeanus]
Length = 689
Score = 75.3 bits (182), Expect = 4e-13
Identities = 55/152 (36%), Positives = 73/152 (47%), Gaps = 29/152 (19%)
Query: 13 NIDTDVIIPARYLNTSDPKELAKHVLEDL----------------DPEFRSKMKPGDIIV 56
N+DTD+IIP ++L T L + L P +RS ++
Sbjct: 533 NVDTDMIIPKQFLKTIKRTGLGSALFYGLRYDPATGAEKPDFVLNQPAYRSSKI---LVC 589
Query: 57 AGENFGCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIG-LPILEAPQAVDRI--- 112
G NFGCGSSREHAP A G+ C+IA SFA IF+ N G LPI+ + + VD +
Sbjct: 590 TGPNFGCGSSREHAPWAFNDFGIRCIIATSFADIFFNNCFKNGMLPIILSQEQVDTLAKY 649
Query: 113 -ETGDELEVDFSSGEIRNLTKGEVYRANPFPD 143
E+EVD +IR GE+ PF D
Sbjct: 650 ATQKAEIEVDLVHQKIR-YPGGEI----PFDD 676
>pir||H81269 probable 3-isopropylmalate dehydratase (EC 4.2.1.33) small chain
Cj1716c [imported] - Campylobacter jejuni (strain NCTC
11168) >gi|6969131|emb|CAB73702.1| (AL139079) putative
3-isopropylmalate dehydratase small subunit
[Campylobacter jejuni]
Length = 200
Score = 74.5 bits (180), Expect = 7e-13
Identities = 49/142 (34%), Positives = 72/142 (50%), Gaps = 18/142 (12%)
Query: 13 NIDTDVIIPARYLNTSDPKELAKHVLEDL----DPEF---------RSKMKPGDIIVAGE 59
NIDTD IIP ++L + KH+ DL D E + + + I+V+ E
Sbjct: 18 NIDTDQIIPKQFLLAVSKQGFGKHLFHDLRYLDDKESVLNMDFNLNKKEYQNSSILVSFE 77
Query: 60 NFGCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIGLPILEAP-----QAVDRIET 114
NFG GSSREHAP A+ G+ +IA SFA IF NA+ GL +E + VD ++
Sbjct: 78 NFGSGSSREHAPWALVDYGIRAIIAPSFADIFKNNALGNGLLTIELAKDEVLEIVDELKK 137
Query: 115 GDELEVDFSSGEIRNLTKGEVY 136
+ ++ S E R K +++
Sbjct: 138 SQDKNIEISLLEKRVFFKDKIF 159
>gb|AAB19612.1| (S57886) isopropylmalate isomerase {EC 4.2.1.33} [Saccharomyces
cerevisiae, Peptide, 782 aa]
Length = 782
Score = 73.7 bits (178), Expect = 1e-12
Identities = 49/136 (36%), Positives = 73/136 (53%), Gaps = 21/136 (15%)
Query: 13 NIDTDVIIPARYLNTSDPKELAKHVL-----------EDLDPEFRSKMKPGD----IIVA 57
N+DTD IIP ++L T L K + +D + +F ++P ++V
Sbjct: 565 NVDTDAIIPKQFLKTIKRTGLKKGLFYEWRFRKDDQGKDQETDFVLNVEPWREAEILVVT 624
Query: 58 GENFGCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIG-LPI-LEAPQAVDRI--- 112
G+NFGCGSSREHAP A+K G+ +IA S+ IFY N+ G LPI L+ +D++
Sbjct: 625 GDNFGCGSSREHAPWALKDFGIKSIIAPSYGDIFYNNSFKNGLLPIRLDQQIIIDKLIPI 684
Query: 113 -ETGDELEVDFSSGEI 127
G +L VD + +I
Sbjct: 685 ANKGGKLCVDLPNQKI 700
>gi|6321429 isopropylmalate isomerase; Leu1p [Saccharomyces cerevisiae]
>gi|1708801|sp|P07264|LEU2_YEAST 3-ISOPROPYLMALATE
DEHYDRATASE (ISOPROPYLMALATE ISOMERASE) (ALPHA-IPM
ISOMERASE) (IPMI) >gi|2131159|pir||S64011
3-isopropylmalate dehydratase (EC 4.2.1.33) - yeast
(Saccharomyces cerevisiae) >gi|1322463|emb|CAA96709.1|
(Z72531) ORF YGL009c [Saccharomyces cerevisiae]
Length = 779
Score = 73.7 bits (178), Expect = 1e-12
Identities = 49/136 (36%), Positives = 73/136 (53%), Gaps = 21/136 (15%)
Query: 13 NIDTDVIIPARYLNTSDPKELAKHVL-----------EDLDPEFRSKMKPGD----IIVA 57
N+DTD IIP ++L T L K + +D + +F ++P ++V
Sbjct: 562 NVDTDAIIPKQFLKTIKRTGLKKGLFYEWRFRKDDQGKDQETDFVLNVEPWREAEILVVT 621
Query: 58 GENFGCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIG-LPI-LEAPQAVDRI--- 112
G+NFGCGSSREHAP A+K G+ +IA S+ IFY N+ G LPI L+ +D++
Sbjct: 622 GDNFGCGSSREHAPWALKDFGIKSIIAPSYGDIFYNNSFKNGLLPIRLDQQIIIDKLIPI 681
Query: 113 -ETGDELEVDFSSGEI 127
G +L VD + +I
Sbjct: 682 ANKGGKLCVDLPNQKI 697
>emb|CAB99455.1| (AJ278693) 3-isopropylmalate dehydratase [Yarrowia lipolytica]
Length = 711
Score = 73.7 bits (178), Expect = 1e-12
Identities = 41/102 (40%), Positives = 58/102 (56%), Gaps = 14/102 (13%)
Query: 13 NIDTDVIIPARYLNTSDPKELAKHVL-----EDLD-----PEFRSKMKPGD----IIVAG 58
N+DTD IIP ++L T L+ + +++D +F + P D ++V+G
Sbjct: 550 NVDTDAIIPKQFLKTIKRTGLSSGLFFEWRFKEVDGKQEKTDFMLNVAPWDKASILVVSG 609
Query: 59 ENFGCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIGL 100
NFGCGSSREHAP A+ G+ C+IA SF IFY N+ GL
Sbjct: 610 NNFGCGSSREHAPWALADFGIRCIIAPSFGDIFYNNSFKNGL 651
>sp|O14289|LEU2_SCHPO 3-ISOPROPYLMALATE DEHYDRATASE (ISOPROPYLMALATE ISOMERASE)
(ALPHA-IPM ISOMERASE) (IPMI) >gi|7489951|pir||T39210
3-isopropylmalate dehydratase - fission yeast
(Schizosaccharomyces pombe) >gi|2414659|emb|CAB16402.1|
(Z99262) 3-isopropylmalate dehydratase
[Schizosaccharomyces pombe]
Length = 758
Score = 73.4 bits (177), Expect = 1e-12
Identities = 46/123 (37%), Positives = 65/123 (52%), Gaps = 12/123 (9%)
Query: 13 NIDTDVIIPARYLNTSDPKELAKHVLEDLD--------PEF---RSKMKPGDIIVAGENF 61
N+DTD IIP ++L T L + ++ P+F R + ++VA +NF
Sbjct: 554 NVDTDKIIPKQFLKTIKRTGLGQFAFYEIRYDADGKEIPDFVLNREPYRHATVLVAHDNF 613
Query: 62 GCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIG-LPILEAPQAVDRIETGDELEV 120
GCGSSREHAP A+ G+ +IA SFA IF+ N G LPI + V+ + E +V
Sbjct: 614 GCGSSREHAPWALNDFGIRVIIAPSFADIFFNNCFKNGMLPIPTPIEQVNDMMKAAENQV 673
Query: 121 DFS 123
FS
Sbjct: 674 KFS 676
>sp|P04787|LEUD_SALTY 3-ISOPROPYLMALATE DEHYDRATASE SMALL SUBUNIT (ISOPROPYLMALATE
ISOMERASE) (ALPHA-IPM ISOMERASE) (IPMI)
>gi|96798|pir||S07306 3-isopropylmalate dehydratase (EC
4.2.1.33) small chain - Salmonella typhimurium
>gi|47764|emb|CAA26364.1| (X02528) IPM isomerase
[Salmonella typhimurium]
Length = 201
Score = 73.0 bits (176), Expect = 2e-12
Identities = 51/149 (34%), Positives = 72/149 (48%), Gaps = 20/149 (13%)
Query: 13 NIDTDVIIPARYLNTSDPKELAKHVLEDL----------DPEFR---SKMKPGDIIVAGE 59
N+DTD IIP ++L H+ D +PEF + + I++A E
Sbjct: 19 NVDTDAIIPKQFLQKVTRTGFGAHLFNDWRFLDEKGQQPNPEFVLNFPEYQGASILLARE 78
Query: 60 NFGCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIG-LPILEAPQAVDRI------ 112
NFGCGSSREHAP A+ G VIA SFA IFY N+ N LP+ + VD +
Sbjct: 79 NFGCGSSREHAPWALTDYGFKVVIAPSFADIFYGNSFNNQLLPVTLSDAQVDELFALVKA 138
Query: 113 ETGDELEVDFSSGEIRNLTKGEVYRANPF 141
G + EVD + ++ K ++ + F
Sbjct: 139 NPGIKFEVDLEAQVVKAGDKTYSFKIDDF 167
>sp|P30126|LEUD_ECOLI 3-ISOPROPYLMALATE DEHYDRATASE SMALL SUBUNIT (ISOPROPYLMALATE
ISOMERASE) (ALPHA-IPM ISOMERASE) (IPMI)
>gi|482061|pir||S40585 3-isopropylmalate dehydratase (EC
4.2.1.33) small chain - Escherichia coli
>gi|216489|dbj|BAA01340.1| (D10483) leuD protein
homolog(PIR:S07306) [Escherichia coli]
>gi|1786258|gb|AAC73182.1| (AE000117) isopropylmalate
isomerase subunit [Escherichia coli K12]
Length = 201
Score = 71.8 bits (173), Expect = 4e-12
Identities = 48/136 (35%), Positives = 67/136 (48%), Gaps = 20/136 (14%)
Query: 13 NIDTDVIIPARYLNTSDPKELAKHVLEDL----------DPEFR---SKMKPGDIIVAGE 59
N+DTD IIP ++L H+ D +P+F + + I++A E
Sbjct: 19 NVDTDAIIPKQFLQKVTRTGFGAHLFNDWRFLDEKGQQPNPDFVLNFPQYQGASILLARE 78
Query: 60 NFGCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIG-LPILEAPQAVDRI------ 112
NFGCGSSREHAP A+ G VIA SFA IFY N+ N LP+ + VD +
Sbjct: 79 NFGCGSSREHAPWALTDYGFKVVIAPSFADIFYGNSFNNQLLPVKLSDAEVDELFALVKA 138
Query: 113 ETGDELEVDFSSGEIR 128
G +VD + E++
Sbjct: 139 NPGIHFDVDLEAQEVK 154
>sp|P55251|LEU2_RHIPU 3-ISOPROPYLMALATE DEHYDRATASE (ISOPROPYLMALATE ISOMERASE)
(ALPHA-IPM ISOMERASE) (IPMI) >gi|1000692|dbj|BAA11052.1|
(D67033) LeuA [Rhizomucor pusillus]
Length = 755
Score = 71.4 bits (172), Expect = 6e-12
Identities = 50/148 (33%), Positives = 72/148 (47%), Gaps = 20/148 (13%)
Query: 13 NIDTDVIIPARYLNTSDPKELAKHVLEDL---------DPEFRSKMKPGD----IIVAGE 59
N+DTD+IIP ++L T L + ++ +P+F +P ++ G
Sbjct: 546 NVDTDMIIPKQFLKTIKRTGLGTALFYNIRFDGATGEENPDFVLNQEPYRQSRILVCTGP 605
Query: 60 NFGCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIGLPILEAPQ-----AVDRIET 114
NFGCGSSREHAP A G+ +IA SFA IF+ N G+ + PQ + +
Sbjct: 606 NFGCGSSREHAPWAFNDFGIRSIIAPSFADIFFNNCFKNGMLPITLPQDKVEMLAEHAKQ 665
Query: 115 GDELEVDFSSGEIRNLTKGEV-YRANPF 141
ELEVD + +R GEV + PF
Sbjct: 666 KAELEVDLVNQVVR-YPGGEVPFDVEPF 692
>sp|P94568|LEUD_BACSU 3-ISOPROPYLMALATE DEHYDRATASE SMALL SUBUNIT (ISOPROPYLMALATE
ISOMERASE) (ALPHA-IPM ISOMERASE) (IPMI)
>gi|7437051|pir||C69650 3-isopropylmalate dehydratase
(small subunit) leuD - Bacillus subtilis
>gi|1770072|emb|CAA99534.1| (Z75208) 3-isopropylmalate
dehydratase, small subunit [Bacillus subtilis]
>gi|2635290|emb|CAB14785.1| (Z99118) 3-isopropylmalate
dehydratase (small subunit) [Bacillus subtilis]
Length = 199
Score = 70.2 bits (169), Expect = 1e-11
Identities = 40/105 (38%), Positives = 55/105 (52%), Gaps = 11/105 (10%)
Query: 13 NIDTDVIIPARYLNTSDPKELAKHVLEDL--------DPEFRSKM---KPGDIIVAGENF 61
N+DTD IIP ++L + + D +PEF + I++AGENF
Sbjct: 18 NVDTDQIIPKQFLKRIERTGYGRFAFFDWRYDANGEPNPEFELNQPVYQGASILIAGENF 77
Query: 62 GCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIGLPILEAP 106
GCGSSREHAP A+ G +IA SFA IF++N G+ + P
Sbjct: 78 GCGSSREHAPWALDDYGFKIIIAPSFADIFHQNCFKNGMLPIRMP 122
>sp|P49601|LEU2_USTMA 3-ISOPROPYLMALATE DEHYDRATASE (ISOPROPYLMALATE ISOMERASE)
(ALPHA-IPM ISOMERASE) (IPMI) >gi|311008|gb|AAA34226.1|
(L20832) LEU1 [Ustilago maydis]
Length = 773
Score = 69.9 bits (168), Expect = 2e-11
Identities = 46/127 (36%), Positives = 65/127 (50%), Gaps = 18/127 (14%)
Query: 13 NIDTDVIIPARYLNTSDPKELAKHVLEDL---------DPEFRSKMKPGD----IIVAGE 59
N+DTD+IIP ++L T L + L DP F KP D ++V G
Sbjct: 559 NVDTDLIIPKQFLKTIKRTGLGSALFWPLRYDAKTGEPDPAFVLNQKPYDQSKILVVTGP 618
Query: 60 NFGCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIG-LPILEAPQAVDRI----ET 114
NFGCGSSREHA ++ G+ VIA+SF IF N G LP++ + + R+ +
Sbjct: 619 NFGCGSSREHAAWSLLDFGIRAVIAESFGDIFRNNLTKNGQLPVVLSRAQIQRLTQDAKA 678
Query: 115 GDELEVD 121
G ++ VD
Sbjct: 679 GKQITVD 685
>sp|P44438|LEUD_HAEIN 3-ISOPROPYLMALATE DEHYDRATASE SMALL SUBUNIT (ISOPROPYLMALATE
ISOMERASE) (ALPHA-IPM ISOMERASE) (IPMI)
>gi|1073788|pir||G64106 3-isopropylmalate dehydratase
(EC 4.2.1.33) small chain - Haemophilus influenzae
(strain Rd KW20) >gi|1574018|gb|AAC22650.1| (U32779)
3-isopropylmalate dehydratase small subunit (leuD)
[Haemophilus influenzae Rd]
Length = 200
Score = 69.1 bits (166), Expect = 3e-11
Identities = 46/132 (34%), Positives = 67/132 (49%), Gaps = 20/132 (15%)
Query: 13 NIDTDVIIPARYLNTSDPKELAKHVLEDL----------DPEF---RSKMKPGDIIVAGE 59
N+DTD IIP ++L KH+ + +PEF + + I++A +
Sbjct: 18 NVDTDAIIPKQFLQAITRIGFGKHLFHEWRYLDVEGTKPNPEFVLNYPQYQGATILLARK 77
Query: 60 NFGCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIG-LPILEAPQAVDRI------ 112
N GCGSSREHAP A+ G +IA SFA IFY N++N LPI + + V+ I
Sbjct: 78 NLGCGSSREHAPWALADYGFKVMIAPSFADIFYNNSLNNHMLPIRLSEEEVEEIFQWVWA 137
Query: 113 ETGDELEVDFSS 124
G ++ VD +
Sbjct: 138 NEGKQIHVDLEA 149
>pir||E81128 3-isopropylmalate dehydratase, small chain NMB1034 [imported] -
Neisseria meningitidis (group B strain MD58)
>gi|7226274|gb|AAF41433.1| (AE002454) 3-isopropylmalate
dehydratase, small subunit [Neisseria meningitidis MC58]
Length = 213
Score = 69.1 bits (166), Expect = 3e-11
Identities = 45/138 (32%), Positives = 68/138 (48%), Gaps = 27/138 (19%)
Query: 13 NIDTDVIIPARYLNTSDPKELAKHVLED-----------------LDPEF---RSKMKPG 52
N+DTD IIP ++L + + ++ L+P+F + + +
Sbjct: 18 NVDTDAIIPKQFLKSIKRSGFGPNAFDEWRYLDHGEPGMDNSKRPLNPDFSLNQPRYQGA 77
Query: 53 DIIVAGENFGCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIG-LPILEAPQAVDR 111
I++ +NFGCGSSREHAP A+ G VIA SFA IF+ N G LPI+ + VDR
Sbjct: 78 QILLTRKNFGCGSSREHAPWALDDYGFRAVIAPSFADIFFNNCYKNGLLPIVLTEERVDR 137
Query: 112 I------ETGDELEVDFS 123
+ G +L +D +
Sbjct: 138 LFKEVEANEGYQLSIDLA 155
>sp|Q9ZEZ5|LEUD_BUCPP 3-ISOPROPYLMALATE DEHYDRATASE SMALL SUBUNIT (ISOPROPYLMALATE
ISOMERASE) (ALPHA-IPM ISOMERASE) (IPMI)
>gi|3900914|emb|CAA07298.1| (AJ006877) 3-isopropylmalate
dehydratase subunit [Buchnera aphidicola]
Length = 207
Score = 68.7 bits (165), Expect = 4e-11
Identities = 47/154 (30%), Positives = 73/154 (46%), Gaps = 20/154 (12%)
Query: 13 NIDTDVIIPARYLNTSDPKELAKHVLED----------LDPEFR---SKMKPGDIIVAGE 59
NIDTD+IIP ++L + K++ + ++P F K K I++ +
Sbjct: 18 NIDTDIIIPKQFLQKVNKLGFGKYLFHNWRFIDENQSQINPNFILNIEKYKKSSILLTRD 77
Query: 60 NFGCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIGLPILEAP-QAVDRI------ 112
NFGCGSSREHA A+ G +IA SF+ IFY N+ N L ++ P +D+
Sbjct: 78 NFGCGSSREHAVWALLDYGFKVIIAPSFSDIFYNNSFNNKLLLITLPNNQIDKFFNIINQ 137
Query: 113 ETGDELEVDFSSGEIRNLTKGEVYRANPFPDFIM 146
G +D EI+ K ++ + F F +
Sbjct: 138 NPGIYFNIDLLKNEIKVEKKIYSFQIDKFRRFCL 171
>pir||C81836 probable 3-isopropylmalate dehydratase (EC 4.2.1.33) small chain
NMA1452 [imported] - Neisseria meningitidis (group A
strain Z2491) >gi|7380105|emb|CAB84688.1| (AL162756)
putative 3-isopropylmalate dehydratase small subunit
[Neisseria meningitidis Z2491]
Length = 213
Score = 68.7 bits (165), Expect = 4e-11
Identities = 42/121 (34%), Positives = 62/121 (50%), Gaps = 21/121 (17%)
Query: 13 NIDTDVIIPARYLNTSDPKELAKHVLED-----------------LDPEF---RSKMKPG 52
N+DTD IIP ++L + + ++ L+P+F + + +
Sbjct: 18 NVDTDAIIPKQFLKSIKRSGFGPNAFDEWRYLDHGEPGMDNSKRPLNPDFSLNQPRYQGA 77
Query: 53 DIIVAGENFGCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIG-LPILEAPQAVDR 111
I++ +NFGCGSSREHAP A+ G VIA SFA IF+ N G LPI+ + VDR
Sbjct: 78 QILLTRKNFGCGSSREHAPWALDDYGFRAVIAPSFADIFFNNCYKNGLLPIVLTEEQVDR 137
Query: 112 I 112
+
Sbjct: 138 L 138
>pir||F83255 3-isopropylmalate dehydratase small subunit PA3120 [imported] -
Pseudomonas aeruginosa (strain PAO1)
>gi|9949232|gb|AAG06508.1|AE004736_5 (AE004736)
3-isopropylmalate dehydratase small subunit [Pseudomonas
aeruginosa]
Length = 212
Score = 67.9 bits (163), Expect = 6e-11
Identities = 44/139 (31%), Positives = 70/139 (49%), Gaps = 27/139 (19%)
Query: 13 NIDTDVIIPARYLNTSDPKELAKHVLED-----------------LDPEF---RSKMKPG 52
N+DTD IIP ++L + ++ ++ L+P+F + + +
Sbjct: 18 NVDTDQIIPKQFLKSIKRTGFGPNLFDEWRYLDVGQPGQDNSKRPLNPDFVLNQPRYQGA 77
Query: 53 DIIVAGENFGCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAINIG-LPILEAPQAVDR 111
+++A ENFGCGSSREHAP A+ G VIA S+A IF+ N+ G LPI+ VD
Sbjct: 78 SVLLARENFGCGSSREHAPWALDEYGFRTVIAPSYADIFFNNSFKNGLLPIILPEAEVDE 137
Query: 112 I------ETGDELEVDFSS 124
+ G +L +D ++
Sbjct: 138 LFRQVEANEGYQLSIDLAA 156
>gi|10954453 isopropylmalate isomerase subunit [Buchnera aphidicola]
>gi|8134538|sp|O85066|LEUD_BUCAP 3-ISOPROPYLMALATE
DEHYDRATASE SMALL SUBUNIT (ISOPROPYLMALATE ISOMERASE)
(ALPHA-IPM ISOMERASE) (IPMI) >gi|3282735|gb|AAD12596.1|
(AF041836) isopropylmalate isomerase subunit [Buchnera
aphidicola]
Length = 207
Score = 67.5 bits (162), Expect = 8e-11
Identities = 38/98 (38%), Positives = 53/98 (53%), Gaps = 13/98 (13%)
Query: 13 NIDTDVIIPARYLNTSDPKELAKHVLED----------LDPEF---RSKMKPGDIIVAGE 59
NIDTD IIP ++L + K++ D ++P F +S K I++ E
Sbjct: 18 NIDTDAIIPKQFLKKVNKIGFGKYLFHDWRFLDKNQLKINPNFILNKSTYKNASILLTRE 77
Query: 60 NFGCGSSREHAPLAIKAAGVSCVIAKSFARIFYRNAIN 97
NFGCGSSREHA ++ G +IA SF+ IFY N+ N
Sbjct: 78 NFGCGSSREHAVWSLLDYGFKVIIASSFSDIFYSNSFN 115
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.320 0.140 0.415
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 65301370
Number of Sequences: 2977
Number of extensions: 2652371
Number of successful extensions: 5382
Number of sequences better than 1.0e-10: 52
Number of HSP's better than 0.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 28
Number of HSP's that attempted gapping in prelim test: 5301
Number of HSP's gapped (non-prelim): 54
length of query: 164
length of database: 189,106,746
effective HSP length: 52
effective length of query: 112
effective length of database: 157,985,422
effective search space: 17694367264
effective search space used: 17694367264
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 162 (67.5 bits)