BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0895 (ilvD) DE:dihydroxy-acid dehydratase (EC 4.2.1.9)
(ilvD)
(551 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||F75045 dihydroxy-acid dehydratase (EC 4.2.1.9) (ilvd) PAB08... 1087 0.0
sp|Q9WZ21|ILVD_THEMA DIHYDROXY-ACID DEHYDRATASE (DAD) >gi|743685... 685 0.0
sp|Q58672|ILVD_METJA DIHYDROXY-ACID DEHYDRATASE (DAD) >gi|212785... 675 0.0
sp|O67009|ILVD_AQUAE DIHYDROXY-ACID DEHYDRATASE (DAD) >gi|743685... 654 0.0
dbj|BAB06781.1| (AP001517) dihydroxy-acid dehydratase [Bacillus ... 629 e-179
gi|11498619 dihydroxy-acid dehydratase (ilvD) [Archaeoglobus ful... 626 e-178
sp|O27498|ILVD_METTH DIHYDROXY-ACID DEHYDRATASE (DAD) 617 e-175
sp|P51785|ILVD_BACSU DIHYDROXY-ACID DEHYDRATASE (DAD) (VEGETATIV... 616 e-175
pir||H69059 dihydroxy-acid dehydratase - Methanobacterium thermo... 532 e-150
pir||H81416 dihydroxy-acid dehydratase (EC 4.2.1.9) Cj0013 [impo... 531 e-150
gb|AAK43209.1| Dihydroxy-acid dehydratase (ilvD) [Sulfolobus sol... 528 e-149
sp|P74689|ILVD_SYNY3 DIHYDROXY-ACID DEHYDRATASE (DAD) >gi|743685... 512 e-144
sp|O07433|ILVD_MYCTU DIHYDROXY-ACID DEHYDRATASE (DAD) >gi|743685... 512 e-144
sp|O06069|ILVD_MYCLE DIHYDROXY-ACID DEHYDRATASE (DAD) >gi|210459... 506 e-142
sp|Q9YG88|ILVD_AERPE DIHYDROXY-ACID DEHYDRATASE (DAD) >gi|743686... 497 e-139
pir||C75432 dihydroxy-acid dehydratase - Deinococcus radiodurans... 488 e-137
sp|P05791|ILVD_ECOLI DIHYDROXY-ACID DEHYDRATASE (DAD) >gi|68303|... 484 e-136
gb|AAF33480.1| (AF233324) S typhimurium dihydroxy-acid dehydrata... 484 e-135
pir||C83601 dihydroxy-acid dehydratase PA0353 [imported] - Pseud... 475 e-133
sp|P44851|ILVD_HAEIN DIHYDROXY-ACID DEHYDRATASE (DAD) >gi|107400... 474 e-133
gb|AAC77491.1| (AE000453) dihydroxyacid dehydratase [Escherichia... 474 e-133
pir||A82850 dihydroxy-acid dehydratase XF0099 [imported] - Xylel... 474 e-133
gb|AAA67574.1| (M87049) dihydroxyacid dehydratase [Escherichia c... 473 e-132
gb|AAG10494.1|AF279106_56 (AF279106) predicted dihydroxyacid deh... 471 e-132
gb|AAF13798.1|AF130812_2 (AF130812) dihydroxy acid dehydratase [... 469 e-131
pir||E81117 dihydroxy-acid dehydratase NMB1150, NMB1188 [importe... 465 e-130
pir||F82374 dihydroxy-acid dehydratase VC0028 [imported] - Vibri... 464 e-129
gb|AAA24023.1| (M32253) ilvD [Escherichia coli] 462 e-129
sp|O69198|ILVD_STRCO DIHYDROXY-ACID DEHYDRATASE (DAD) >gi|319288... 462 e-129
pir||C81905 probable dihydroxy-acid dehydratase (EC 4.2.1.9) NMA... 462 e-129
pir||T36294 dihydroxy-acid dehydratase - Streptomyces coelicolor... 461 e-129
sp|Q10318|ILV3_SCHPO PUTATIVE DIHYDROXY-ACID DEHYDRATASE, MITOCH... 458 e-128
dbj|BAB03011.1| (AP001297) dihydroxy-acid dehydratase [Arabidops... 458 e-128
gb|AAF13806.1|AF130814_2 (AF130814) dihydroxy acid dehydratase [... 456 e-127
emb|CAB57218.1| (AJ012293) dihydroxy-acid dehydratase [Corynebac... 455 e-127
sp|P57656|ILVD_BUCAI DIHYDROXY-ACID DEHYDRATASE (DAD) >gi|100392... 451 e-126
sp|O51887|ILVD_BUCAP DIHYDROXY-ACID DEHYDRATASE (DAD) >gi|282703... 446 e-124
gb|AAF13802.1|AF130813_2 (AF130813) dihydroxy acid dehydratase [... 444 e-124
sp|Q02139|ILVD_LACLA DIHYDROXY-ACID DEHYDRATASE (DAD) >gi|486729... 438 e-122
gi|6322476 dihydroxyacid dehydratase; Ilv3p [Saccharomyces cerev... 437 e-121
pir||T43179 probable dehydratase (EC 4.2.1.-) - fission yeast (... 435 e-121
sp|P31959|ILVD_CLOPA DIHYDROXY-ACID DEHYDRATASE (DAD) >gi|144843... 380 e-104
pir||T36902 probable dihydroxy-acid dehydratase - Streptomyces c... 368 e-101
emb|CAB61588.1| (AL133210) putative dihydroxy-acid dehydratase [... 363 4e-99
sp|Q9XBI3|ILVD_BACCE DIHYDROXY-ACID DEHYDRATASE (DAD) >gi|458411... 351 2e-95
gb|AAA34568.1| (L13975) dihydroxyacid dehydratase [Saccharomyces... 272 6e-72
sp|P21909|EDD_ZYMMO PHOSPHOGLUCONATE DEHYDRATASE (6-PHOSPHOGLUCO... 246 4e-64
pir||G83246 phosphogluconate dehydratase PA3194 [imported] - Pse... 245 7e-64
sp|P31961|EDD_PSEAE PHOSPHOGLUCONATE DEHYDRATASE (6-PHOSPHOGLUCO... 242 8e-63
pir||A81088 phosphogluconate dehydratase NMB1393 [imported] - Ne... 239 5e-62
pir||C82727 6-phosphogluconate dehydratase XF1062 [imported] - X... 239 5e-62
pir||F81854 phosphogluconate dehydratase (EC 4.2.1.12) NMA1610 [... 238 9e-62
sp|P77596|YAGF_ECOLI HYPOTHETICAL 69.4 KD PROTEIN IN PERR-ARGF I... 235 8e-61
sp|P25530|EDD_ECOLI PHOSPHOGLUCONATE DEHYDRATASE (6-PHOSPHOGLUCO... 235 1e-60
pir||A42986 phosphogluconate dehydratase (EC 4.2.1.12) - Escheri... 233 3e-60
sp|Q9Z3S0|EDD_RHIME PHOSPHOGLUCONATE DEHYDRATASE (6-PHOSPHOGLUCO... 230 3e-59
gi|10955076 mocB [Agrobacterium tumefaciens] >gi|11268880|pir||T... 228 2e-58
sp|P39358|YJHG_ECOLI HYPOTHETICAL 70.0 KD PROTEIN IN FECI-FIMB I... 218 2e-55
pir||G82340 phosphogluconate dehydratase VC0288 [imported] - Vib... 215 1e-54
pir||S56522 hypothetical protein f655 - Escherichia coli >gi|537... 212 7e-54
sp|Q9ZKB3|EDD_HELPJ PHOSPHOGLUCONATE DEHYDRATASE (6-PHOSPHOGLUCO... 204 3e-51
sp|P56111|EDD_HELPY PHOSPHOGLUCONATE DEHYDRATASE (6-PHOSPHOGLUCO... 203 6e-51
emb|CAA70985.1| (Y09856) dihydroxy-acid dehydratase [Methanother... 193 4e-48
gb|AAA23863.1| (L20897) 6-phosphogluconate dehydratase [Escheric... 157 3e-37
emb|CAA26263.1| (X02413) pot. unidentified reading frame [Escher... 97 6e-19
sp|P55186|ILVD_CAUCR DIHYDROXY-ACID DEHYDRATASE (DAD) >gi|107287... 72 1e-11
>pir||F75045 dihydroxy-acid dehydratase (EC 4.2.1.9) (ilvd) PAB0895 - Pyrococcus
abyssi (strain Orsay) >gi|5458772|emb|CAB50259.1|
(AJ248287) dihydroxy-acid dehydratase (EC 4.2.1.9)
(ilvD) [Pyrococcus abyssi]
Length = 551
Score = 1087 bits (2780), Expect = 0.0
Identities = 551/551 (100%), Positives = 551/551 (100%)
Query: 1 MRSDVIKKGIERAPHRALFKAMGLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTG 60
MRSDVIKKGIERAPHRALFKAMGLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTG
Sbjct: 1 MRSDVIKKGIERAPHRALFKAMGLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTG 60
Query: 61 VRMSGGTPLEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCD 120
VRMSGGTPLEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCD
Sbjct: 61 VRMSGGTPLEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCD 120
Query: 121 KIIPGMLMAMARLDIPAIFISGGPMLPGRFKGEYVDVKTVFEAVGAVKAGKMSEKELKLL 180
KIIPGMLMAMARLDIPAIFISGGPMLPGRFKGEYVDVKTVFEAVGAVKAGKMSEKELKLL
Sbjct: 121 KIIPGMLMAMARLDIPAIFISGGPMLPGRFKGEYVDVKTVFEAVGAVKAGKMSEKELKLL 180
Query: 181 EDFACPGCGSCAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKLVE 240
EDFACPGCGSCAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKLVE
Sbjct: 181 EDFACPGCGSCAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKLVE 240
Query: 241 EDLKPSDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFDEISEKTPTL 300
EDLKPSDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFDEISEKTPTL
Sbjct: 241 EDLKPSDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFDEISEKTPTL 300
Query: 301 VKISPAGKHFVLDLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVGELLRDVSVLRDDVI 360
VKISPAGKHFVLDLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVGELLRDVSVLRDDVI
Sbjct: 301 VKISPAGKHFVLDLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVGELLRDVSVLRDDVI 360
Query: 361 RPVTRPYLSRGGLMILYGSLAPKGAVLKVSAIPDIETFEGEARVFDCEEDAVKAILSGDI 420
RPVTRPYLSRGGLMILYGSLAPKGAVLKVSAIPDIETFEGEARVFDCEEDAVKAILSGDI
Sbjct: 361 RPVTRPYLSRGGLMILYGSLAPKGAVLKVSAIPDIETFEGEARVFDCEEDAVKAILSGDI 420
Query: 421 EKGDVVVIRYEGPKGGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIGHVSP 480
EKGDVVVIRYEGPKGGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIGHVSP
Sbjct: 421 EKGDVVVIRYEGPKGGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIGHVSP 480
Query: 481 EAAEGGPIALVEDGDLIRIDVKAKRIDLLVDEEELKERKAKWKPKVKEVKGYLKRYSSLV 540
EAAEGGPIALVEDGDLIRIDVKAKRIDLLVDEEELKERKAKWKPKVKEVKGYLKRYSSLV
Sbjct: 481 EAAEGGPIALVEDGDLIRIDVKAKRIDLLVDEEELKERKAKWKPKVKEVKGYLKRYSSLV 540
Query: 541 TSANTGAVFRE 551
TSANTGAVFRE
Sbjct: 541 TSANTGAVFRE 551
>sp|Q9WZ21|ILVD_THEMA DIHYDROXY-ACID DEHYDRATASE (DAD) >gi|7436852|pir||E72362
dihydroxy-acid dehydratase - Thermotoga maritima (strain
MSB8) >gi|4981066|gb|AAD35636.1|AE001730_4 (AE001730)
dihydroxy-acid dehydratase [Thermotoga maritima]
Length = 554
Score = 685 bits (1749), Expect = 0.0
Identities = 333/553 (60%), Positives = 428/553 (77%), Gaps = 2/553 (0%)
Query: 1 MRSDVIKKGIERAPHRALFKAMGLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTG 60
MRSDVIKKG+ER PHR+L KA+G+TD+E+ +P IGIV+S+NE+IPGH+HL ++ EAVK G
Sbjct: 1 MRSDVIKKGLERVPHRSLLKALGITDDEMRRPFIGIVSSWNEIIPGHVHLDKVVEAVKAG 60
Query: 61 VRMSGGTPLEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCD 120
VRM+GG P F TIGICDGIAM H GMK+SLPSRELIADSIE V + FDG+V + +CD
Sbjct: 61 VRMAGGVPFVFPTIGICDGIAMDHRGMKFSLPSRELIADSIEIVASGFPFDGLVFVPNCD 120
Query: 121 KIIPGMLMAMARLDIPAIFISGGPMLPGRFKGEYVDVKTVFEAVGAVKAGKMSEKELKLL 180
KI PGM+MAM RL+IP++ ISGGPML GR+ G +D+ TVFEAVG K GK+ E+ LK +
Sbjct: 121 KITPGMMMAMGRLNIPSVLISGGPMLAGRYNGRDIDLITVFEAVGGYKVGKVDEETLKAI 180
Query: 181 EDFACPGCGSCAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKLVE 240
ED ACPG GSCAG+FTANTMN+L EALGI+ NGT PAV+A R+R+AK+ GM +++LV+
Sbjct: 181 EDLACPGAGSCAGLFTANTMNSLAEALGIAPRGNGTVPAVHAKRLRMAKEAGMLVVELVK 240
Query: 241 EDLKPSDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFDEISEKTPTL 300
D+KP DI+T ++F +A+ VD+A GGSTNTVLHL AIA G+ + FDE+S K P +
Sbjct: 241 RDVKPRDIVTLDSFMNAVMVDLATGGSTNTVLHLKAIAESFGIDFDIKLFDELSRKIPHI 300
Query: 301 VKISPAGKHFVLDLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVGELLRDVSVLRDDVI 360
ISP G + + DL +AGG+ A+MKRL E GL+ ED +T+ L+ +G+L+R+ +L +DVI
Sbjct: 301 CNISPVGPYHIQDLDDAGGIYAVMKRLQENGLLKEDVMTIYLRKIGDLVREAKILNEDVI 360
Query: 361 RPVTRPYLSRGGLMILYGSLAPKGAVLKVSAIPD-IETFEGEARVFDCEEDAVKAILSGD 419
RP PY GGL IL+G+LAP+GAV K+S +P+ + G A VF+ E+A KAILSG
Sbjct: 361 RPFDNPYHKEGGLGILFGNLAPEGAVAKLSGVPEKMMHHVGPAVVFEDGEEATKAILSGK 420
Query: 420 IEKGDVVVIRYEGPKGGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIGHVS 479
I+KGDVVVIRYEGPKGGPGMREML+PTSAI GMGL DVAL+TDGRFSG + G IGHVS
Sbjct: 421 IKKGDVVVIRYEGPKGGPGMREMLSPTSAIVGMGLAEDVALITDGRFSGGSHGAVIGHVS 480
Query: 480 PEAAEGGPIALVEDGDLIRIDVKAKRIDLLVDEEELKERKAKWKPKVKEV-KGYLKRYSS 538
PEAAEGGPI +V+DGDLI ID + + ++LL+ +EE + R ++ P VKEV YL+RY+
Sbjct: 481 PEAAEGGPIGIVKDGDLIEIDFEKRTLNLLISDEEFERRMKEFTPLVKEVDSDYLRRYAF 540
Query: 539 LVTSANTGAVFRE 551
V SA+ GA+FR+
Sbjct: 541 FVQSASKGAIFRK 553
>sp|Q58672|ILVD_METJA DIHYDROXY-ACID DEHYDRATASE (DAD) >gi|2127851|pir||C64459
dihydroxy-acid dehydratase (EC 4.2.1.9) - Methanococcus
jannaschii >gi|1591912|gb|AAB99282.1| (U67568)
dihydroxy-acid dehydratase (ilvD) [Methanococcus
jannaschii]
Length = 561
Score = 675 bits (1723), Expect = 0.0
Identities = 336/553 (60%), Positives = 428/553 (76%), Gaps = 5/553 (0%)
Query: 1 MRSDVIKKGIERAPHRALFKAMGLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTG 60
M SD +KKG++RAP+R+L KA G TDEEL++P IG+VNSF E++PGHIHLR IAEAVK G
Sbjct: 9 MISDRVKKGLKRAPNRSLLKACGYTDEELERPFIGVVNSFTEVVPGHIHLRDIAEAVKKG 68
Query: 61 VRMSGGTPLEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCD 120
+ +GGT EF+T+ ICDGIAMGH GMKYSLPSRE+IAD++E++ +A+ FDG+V+I SCD
Sbjct: 69 IYANGGTAFEFNTMAICDGIAMGHEGMKYSLPSREIIADTVESMAKAHGFDGLVLIPSCD 128
Query: 121 KIIPGMLMAMARLDIPAIFISGGPMLPGRFKGEYVDVKTVFEAVGAVKAGKMSEKELKLL 180
KI+PGM+M R +P I ++GGPM PG +G+ D+ +VFE VGA AGK++E+ELK +
Sbjct: 129 KIVPGMIMGAIRTGLPFIVVTGGPMFPGELRGKKYDLISVFEGVGACAAGKITEEELKEI 188
Query: 181 EDFACPGCGSCAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKLVE 240
ED ACPG GSCAG+FTANTM LTEA+G+SLP+ T+ A A +IRIAK++GM+I+ LV
Sbjct: 189 EDIACPGAGSCAGLFTANTMACLTEAMGLSLPYCATSHATTAEKIRIAKRSGMRIVDLVR 248
Query: 241 EDLKPSDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVK-LTLDTFDEISEKTPT 299
++ P ILT EAFE+AI VD+ALGGSTNT LH+ AIA E K +TLD FD +S + P
Sbjct: 249 NNITPDKILTKEAFENAILVDLALGGSTNTTLHIPAIANEVKPKFITLDDFDRLSGEVPH 308
Query: 300 LVKISPAGKHFVLDLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVGELLRDVSVLRDDV 359
+ + P G+HF++DL+ AGG+ A++K L E I ++ +TVS KT+GE++++V + V
Sbjct: 309 IASLRPGGEHFIIDLHRAGGIPAVLKVLEE--KIRKECLTVSGKTIGEIIKEVKYIDYSV 366
Query: 360 IRPVTRPYLSRGGLMILYGSLAPKGAVLKVSAI-PDIETFEGEARVFDCEEDAVKAILSG 418
IRPV P GL IL GSLAP GAV+K+ A+ P + EG ARVFD EE+AV AIL G
Sbjct: 367 IRPVDNPVHETAGLRILKGSLAPNGAVVKIGAVNPKMYKHEGPARVFDSEEEAVDAILGG 426
Query: 419 DIEKGDVVVIRYEGPKGGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIGHV 478
DIE+GDVVVIRYEGP GGPGMREMLAPTSAI GMGLD VAL+TDGRFSG +RG IGHV
Sbjct: 427 DIERGDVVVIRYEGPAGGPGMREMLAPTSAICGMGLDDSVALITDGRFSGGSRGPCIGHV 486
Query: 479 SPEAAEGGPIALVEDGDLIRIDVKAKRIDLLVDEEELKERKAKW-KPKVKEVKGYLKRYS 537
SPEA GGPIA+VEDGD+I+ID+ K++DL +DEEE+KER AKW KP+ K KGYL RY+
Sbjct: 487 SPEAMAGGPIAIVEDGDIIKIDMINKKLDLALDEEEIKERLAKWKKPEPKVKKGYLARYA 546
Query: 538 SLVTSANTGAVFR 550
LV+SA+ GAV R
Sbjct: 547 KLVSSADEGAVLR 559
>sp|O67009|ILVD_AQUAE DIHYDROXY-ACID DEHYDRATASE (DAD) >gi|7436851|pir||F70372
dihydroxyacid dehydratase - Aquifex aeolicus
>gi|2983386|gb|AAC06971.1| (AE000710) dihydroxyacid
dehydratase [Aquifex aeolicus]
Length = 555
Score = 654 bits (1670), Expect = 0.0
Identities = 317/549 (57%), Positives = 416/549 (75%), Gaps = 2/549 (0%)
Query: 2 RSDVIKKGIERAPHRALFKAMGLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTGV 61
RSD +KKGIERAPHRAL +A GL+DE+ DKPLIGI NS+ ++IPGH+HLR E +K V
Sbjct: 4 RSDKVKKGIERAPHRALLRACGLSDEDFDKPLIGIANSYIDIIPGHVHLREFVEPIKEEV 63
Query: 62 RMSGGTPLEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCDK 121
R GG P+EF+ IG+ DGIAMGH GM YSLPSRELIADSIE VV A+ D ++ I +CDK
Sbjct: 64 RKLGGVPIEFNVIGVDDGIAMGHEGMHYSLPSRELIADSIETVVNAHQLDALICIPNCDK 123
Query: 122 IIPGMLMAMARLDIPAIFISGGPMLPGRFKGEYVDVKTVFEAVGAVKAGKMSEKELKLLE 181
I+PGMLM R+++P +FISGGPML G G+ VD+ +VFE +G VK G++SE+ELK++E
Sbjct: 124 IVPGMLMGALRVNVPTVFISGGPMLAGEVNGQKVDLISVFEGIGKVKRGEISEQELKVIE 183
Query: 182 DFACPGCGSCAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKLVEE 241
ACP CGSC+GMFTAN+MN LTE LG++LP NGT A+ R +A+ + +L+E+
Sbjct: 184 ASACPTCGSCSGMFTANSMNCLTEVLGLALPGNGTILAIDPRREILARNAVKALFELLEK 243
Query: 242 DLKPSDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFDEISEKTPTLV 301
D+KP DI+T EA +DA VD+A+GGS+NT+LHL+AIAREAG++ L +EIS++TPT+
Sbjct: 244 DVKPRDIVTEEALDDAFTVDIAMGGSSNTILHLLAIAREAGIEYNLAKINEISKRTPTIC 303
Query: 302 KISPAGKHFVLDLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVGELLRDVSVLRDDVIR 361
KISPA + + DL GG+ IMK LS+LGL+H +R TVS KT+GE++ D +V+R
Sbjct: 304 KISPASHYHIEDLDRVGGIPTIMKELSKLGLLHTERKTVSGKTIGEIISDAPDADGEVVR 363
Query: 362 PVTRPYLSRGGLMILYGSLAPKGAVLKVSAI-PDIETFEGEARVFDCEEDAVKAILSGDI 420
+ PY GG+ IL+G+LAP+GAV+K + + P + TF+G+A FD EE+A++ IL G +
Sbjct: 364 TIENPYSKDGGIAILFGNLAPEGAVVKTAGVDPKMLTFKGKAICFDSEEEAIEGILGGKV 423
Query: 421 EKGDVVVIRYEGPKGGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIGHVSP 480
+ G VVVIRYEGPKGGPGMREML+PTSAI GMGL VAL+TDGRFSG TRG +GH+SP
Sbjct: 424 KPGHVVVIRYEGPKGGPGMREMLSPTSAIMGMGLGDKVALITDGRFSGGTRGACVGHISP 483
Query: 481 EAAEGGPIALVEDGDLIRIDVKAKRIDLLVDEEELKERKAKWKPKVKEVK-GYLKRYSSL 539
EAA GGPI +V+DGD I ID+ +RI+LL+ EEE ER +KPK KE+K +L+RY+ L
Sbjct: 484 EAAAGGPIGIVKDGDEILIDIPNRRIELLISEEEFNERMKNFKPKQKEIKSSWLRRYAKL 543
Query: 540 VTSANTGAV 548
VTSA+ GA+
Sbjct: 544 VTSASKGAI 552
>dbj|BAB06781.1| (AP001517) dihydroxy-acid dehydratase [Bacillus halodurans]
Length = 555
Score = 629 bits (1605), Expect = e-179
Identities = 311/554 (56%), Positives = 414/554 (74%), Gaps = 4/554 (0%)
Query: 1 MRSDVIKKGIERAPHRALFKAMGLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTG 60
MRSD+IKKGI+RAPHR+L +A G+ +EE+DKP IG+ NS+ ++IPGH+HL + AE K
Sbjct: 1 MRSDMIKKGIDRAPHRSLLRAAGVKEEEMDKPFIGVCNSYIDIIPGHMHLNKFAEVAKEA 60
Query: 61 VRMSGGTPLEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCD 120
+R +GG P EF+TIG+ DGIAMGH GM+YSLPSRE+I D+ E V+ A+ FDG+ I +CD
Sbjct: 61 IREAGGIPFEFNTIGVDDGIAMGHIGMRYSLPSREIICDAAETVINAHWFDGVFFIPNCD 120
Query: 121 KIIPGMLMAMARLDIPAIFISGGPMLPGRFK-GEYVDVKTVFEAVGAVKAGKMSEKELKL 179
KI PGMLMA R ++P++F+SGGPM GR K G+ + + +VFE VGA +GKM+ +EL
Sbjct: 121 KITPGMLMASVRTNVPSVFVSGGPMEAGRTKDGKNLSLASVFEGVGAFSSGKMTREELLE 180
Query: 180 LEDFACPGCGSCAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKLV 239
+E ACP CGSC+GMFTAN+MN+L E LG++LP NGT A R ++ K +M L+
Sbjct: 181 IEQTACPTCGSCSGMFTANSMNSLMEMLGMALPGNGTIVATSEARHQLIKDAAKHLMNLI 240
Query: 240 EEDLKPSDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFDEISEKTPT 299
E+D++P DI+T E +DA A+DMA+GGSTNTVLH +AIA EA ++ L+ +E++E+ P
Sbjct: 241 EKDIRPRDIITKETIDDAFALDMAMGGSTNTVLHTLAIANEAEIEYDLNRINEVAERVPY 300
Query: 300 LVKISPAGKHFVLDLYEAGGVLAIMKRLSEL-GLIHEDRITVSLKTVGELLRDVSVLRDD 358
L KISPA + + D++ AGGV AI+K L E+ G IH DRIT++ K++ E ++D + D
Sbjct: 301 LCKISPASDYSMDDVHHAGGVAAIIKELCEIDGAIHPDRITITGKSIYENVKDAEITDDV 360
Query: 359 VIRPVTRPYLSRGGLMILYGSLAPKGAVLKVSAI-PDIETFEGEARVFDCEEDAVKAILS 417
VIR PY GGL IL+G+LAP GAV+KV A+ P I+ FEGEA V++ +E+A + I +
Sbjct: 361 VIRRKDNPYSPVGGLSILFGNLAPNGAVIKVGAVDPSIQIFEGEAIVYNSQEEAQQGINN 420
Query: 418 GDIEKGDVVVIRYEGPKGGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIGH 477
GD+ +G VVVIRYEGPKGGPGM EMLAPTSAI G GL VAL+TDGRFSGA+RG+SIGH
Sbjct: 421 GDVREGHVVVIRYEGPKGGPGMPEMLAPTSAIIGRGLGTKVALITDGRFSGASRGISIGH 480
Query: 478 VSPEAAEGGPIALVEDGDLIRIDVKAKRIDLLVDEEELKERKAKW-KPKVKEVKGYLKRY 536
+SPEAAEGGPIA +E+GD IRID+ + I+ LV +EE+ +R+ W +P+ K KGYL RY
Sbjct: 481 ISPEAAEGGPIAFIENGDKIRIDLPNRTIEWLVSDEEIAKRQEGWTEPEPKVKKGYLARY 540
Query: 537 SSLVTSANTGAVFR 550
S LVTSANTG V +
Sbjct: 541 SKLVTSANTGGVMK 554
>gi|11498619 dihydroxy-acid dehydratase (ilvD) [Archaeoglobus fulgidus]
>gi|6685559|sp|O29248|ILVD_ARCFU DIHYDROXY-ACID
DEHYDRATASE (DAD) >gi|7436850|pir||F69376 dihydroxy-acid
dehydratase (ilvD) homolog - Archaeoglobus fulgidus
>gi|2649582|gb|AAB90229.1| (AE001034) dihydroxy-acid
dehydratase (ilvD) [Archaeoglobus fulgidus]
Length = 547
Score = 626 bits (1596), Expect = e-178
Identities = 313/549 (57%), Positives = 415/549 (75%), Gaps = 7/549 (1%)
Query: 1 MRSDVIKKGIERAPHRALFKAMGLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTG 60
MRSD +KKGI+R HRAL KA+G+TD+E+DKP IG+ N++N ++PGH+ L ++ +AVK G
Sbjct: 1 MRSDEVKKGIDRVAHRALLKALGVTDDEMDKPFIGVANAYNTIVPGHMTLDKLTQAVKEG 60
Query: 61 VRMSGGTPLEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCD 120
V +GG P EF IGICDGIAMGH GM +SLPSREL+AD+IEA+V A+ FDG+V++ASCD
Sbjct: 61 VYAAGGVPFEFGIIGICDGIAMGHEGMCFSLPSRELVADTIEAMVEAHRFDGLVVVASCD 120
Query: 121 KIIPGMLMAMARLDIPAIFISGGPMLPGRFKGEYVDVKTVFEAVGAVKAGKMSEKELKLL 180
KIIPGMLMAM RL+IPAI ++GGPM R GE V +K FEA G KAGK+ + LKL
Sbjct: 121 KIIPGMLMAMLRLNIPAIAVTGGPMPYERVGGEKVSIKDAFEAAGMYKAGKLDDAGLKLY 180
Query: 181 EDFACPGCGSCAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKLVE 240
ED+ P CGSC G++TAN+M LTE LG+SLP+ T+P + ++RIAKQ+G ++++LV
Sbjct: 181 EDYCAPYCGSCQGLYTANSMQILTETLGLSLPYCSTSPCPSSRKLRIAKQSGKRVVELVM 240
Query: 241 EDLKPSDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFDEISEKTPTL 300
+++KP D + +FE+AI +DM +GGSTNTVLHL AIA+EAG++L+LD FDEIS +TP +
Sbjct: 241 QNIKPLDFVNERSFENAITMDMLVGGSTNTVLHLPAIAKEAGIRLSLDLFDEISRRTPHI 300
Query: 301 VKISPAGKHFVLDLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVGELLRDVSVLRD-DV 359
V I PA K V+DL E+GGV ++K+ + D +TVS KT+ E + +++VLR D+
Sbjct: 301 VSIDPASKEMVVDLDESGGVPMLIKKARK---YFHDEMTVSGKTLYE-IAEMAVLRGRDI 356
Query: 360 IRPVTRPYLSRGGLMILYGSLAPKGAVLKVSAI-PDIETFEGEARVFDCEEDAVKAILSG 418
I P GG+ IL G+LA GAV+K +A+ D+ FEG A+V+D E++A+ AIL G
Sbjct: 357 IASPDNPLHKEGGIAILKGNLAENGAVIKAAAVSEDMMRFEGTAKVYDSEKEALNAILDG 416
Query: 419 DIEKGDVVVIRYEGPKGGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIGHV 478
+E+GDVVVIRY GPKG PGM EML PT+AI+G+GL + VAL+TDGRFSGATRG IGHV
Sbjct: 417 KVEEGDVVVIRYMGPKGAPGMPEMLLPTAAISGLGLQK-VALITDGRFSGATRGPCIGHV 475
Query: 479 SPEAAEGGPIALVEDGDLIRIDVKAKRIDLLVDEEELKERKAKWKPKVKEVKGYLKRYSS 538
SPEAA GG IALVEDGD I ID+ A+++++ + +EEL ER+AKWKPK KE+KGYL +Y+
Sbjct: 476 SPEAAVGGNIALVEDGDKISIDIPARKLEVKLSDEELAERRAKWKPKEKELKGYLAKYAK 535
Query: 539 LVTSANTGA 547
LV A GA
Sbjct: 536 LVRGAEEGA 544
>sp|O27498|ILVD_METTH DIHYDROXY-ACID DEHYDRATASE (DAD)
Length = 549
Score = 617 bits (1574), Expect = e-175
Identities = 312/553 (56%), Positives = 419/553 (75%), Gaps = 7/553 (1%)
Query: 1 MRSDVIKKGIERAPHRALFKAMGLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTG 60
M+SD IK+GI+RAPHR+L GLTD++ +KP IGI NS+ +++PGHIHLR +AEAVK G
Sbjct: 1 MKSDTIKRGIQRAPHRSLLARCGLTDDDFEKPFIGIANSYTDIVPGHIHLRELAEAVKEG 60
Query: 61 VRMSGGTPLEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCD 120
V +GG EF+T+ ICDGIAM H GMKYSL SRE++AD++E++ A+ DG+V++ +CD
Sbjct: 61 VNAAGGVAFEFNTMAICDGIAMNHDGMKYSLASREIVADTVESMAMAHALDGLVLLPTCD 120
Query: 121 KIIPGMLMAMARLDIPAIFISGGPMLPGRFKGEYVDVKTVFEAVGAVKAGKMSEKELKLL 180
KI+PGMLMA ARLDIPAI ++GGPMLPG FKG VD+ V+E VG V AG+MSE EL+ L
Sbjct: 121 KIVPGMLMAAARLDIPAIVVTGGPMLPGEFKGRKVDLINVYEGVGTVSAGEMSEDELEEL 180
Query: 181 EDFACPGCGSCAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKLVE 240
E ACPG SCAG+FTANTM LTEALG+SLP TA AV + + +IA+ +G +I+++V+
Sbjct: 181 ERCACPGPRSCAGLFTANTMACLTEALGMSLPGCATAHAVSSRKRQIARLSGKRIVEMVQ 240
Query: 241 EDLKPSDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREA-GVKLTLDTFDEISEKTPT 299
E+LKP+ I++ EAFE+A+ VD+ALGGSTNT LH+ AIA E G+ + LD FDE+S P
Sbjct: 241 ENLKPTMIMSQEAFENAVMVDLALGGSTNTTLHIPAIAAEIDGLNINLDLFDELSRVIPH 300
Query: 300 LVKISPAGKHFVLDLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVGELLRDVSVLRDDV 359
+ ISPAG+H +LDL AGG+ A++K L + I+ + +T + +TV E + +V V DV
Sbjct: 301 IASISPAGEHMMLDLDRAGGIPAVLKTLED--HINRECVTCTGRTVQENIENVKVGHRDV 358
Query: 360 IRPVTRPYLSRGGLMILYGSLAPKGAVLKVSAI-PDIETFEGEARVFDCEEDAVKAILSG 418
IRP+ P S GGL IL G+LAP+G+V+K A+ D+ EG A+VF+ E++ ++AI G
Sbjct: 359 IRPLDSPVHSEGGLAILRGNLAPRGSVVKQGAVAEDMMVHEGPAKVFNSEDECMEAIFGG 418
Query: 419 DIEKGDVVVIRYEGPKGGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIGHV 478
I++GDV+VIRYEGPKGGPGMREML PTSAIAGMGL+R VAL+TDGRFSG TRG +GHV
Sbjct: 419 RIDEGDVIVIRYEGPKGGPGMREMLNPTSAIAGMGLER-VALITDGRFSGGTRGPCVGHV 477
Query: 479 SPEAAEGGPIALVEDGDLIRIDVKAKRIDLLVDEEELKER-KAKWKPKVKEVKGYLKRYS 537
SPEA E GP+A V DGD+IRID+ ++++++ + E++ER ++ KP+ + VKG+L RY
Sbjct: 478 SPEAMEDGPLAAVNDGDIIRIDIPSRKLEVDLSPREIEERLQSAVKPR-RSVKGWLARYR 536
Query: 538 SLVTSANTGAVFR 550
L SA+TGAV R
Sbjct: 537 KLAGSADTGAVLR 549
>sp|P51785|ILVD_BACSU DIHYDROXY-ACID DEHYDRATASE (DAD) (VEGETATIVE PROTEIN 110) (VEG110)
>gi|7436848|pir||D69644 dihydroxy-acid dehydratase ilvD
- Bacillus subtilis >gi|1256635|gb|AAA96629.1| (L77246)
dihydroxy-acid dehydratase [Bacillus subtilis]
>gi|2634607|emb|CAB14105.1| (Z99115) dihydroxy-acid
dehydratase [Bacillus subtilis]
Length = 558
Score = 616 bits (1571), Expect = e-175
Identities = 303/556 (54%), Positives = 414/556 (73%), Gaps = 8/556 (1%)
Query: 1 MRSDVIKKGIERAPHRALFKAMGLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTG 60
+RS++I +GI+RAPHR+L +A G+ +E+ KP I + NS+ +++PGH+HL+ + VK
Sbjct: 4 LRSNMITQGIDRAPHRSLLRAAGVKEEDFGKPFIAVCNSYIDIVPGHVHLQEFGKIVKEA 63
Query: 61 VRMSGGTPLEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCD 120
+R +GG P EF+TIG+ DGIAMGH GM+YSLPSRE+IADS+E VV A+ FDG+V I +CD
Sbjct: 64 IREAGGVPFEFNTIGVDDGIAMGHIGMRYSLPSREIIADSVETVVSAHWFDGMVCIPNCD 123
Query: 121 KIIPGMLMAMARLDIPAIFISGGPMLPGRFK-GEYVDVKTVFEAVGAVKAGKMSEKELKL 179
KI PGMLMA R++IP IF+SGGPM GR G + + +VFE VGA +AGK++E EL+
Sbjct: 124 KITPGMLMAAMRINIPTIFVSGGPMAAGRTSYGRKISLSSVFEGVGAYQAGKINENELQE 183
Query: 180 LEDFACPGCGSCAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKLV 239
LE F CP CGSC+GMFTAN+MN L+EALG++LP NGT A R +++ Q+M+ +
Sbjct: 184 LEQFGCPTCGSCSGMFTANSMNCLSEALGLALPGNGTILATSPERKEFVRKSAAQLMETI 243
Query: 240 EEDLKPSDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFDEISEKTPT 299
+D+KP DI+T +A ++A A+DMALGGSTNTVLH +A+A EAGV+ +L+ +E++E+ P
Sbjct: 244 RKDIKPRDIVTVKAIDNAFALDMALGGSTNTVLHTLALANEAGVEYSLERINEVAERVPH 303
Query: 300 LVKISPAGKHFVLDLYEAGGVLAIMKRLSEL-GLIHEDRITVSLKTVGELLRDVSVLRDD 358
L K++PA F+ DL+EAGGV A + LS+ G +H D +TV+ KT+GE + V D
Sbjct: 304 LAKLAPASDVFIEDLHEAGGVSAALNELSKKEGALHLDALTVTGKTLGETIAGHEVKDYD 363
Query: 359 VIRPVTRPYLSRGGLMILYGSLAPKGAVLKVSAIPD-IETFEGEARVFDCEEDAVKAILS 417
VI P+ +P+ +GGL +L+G+LAP GA++K + + I EG A VFD +++A+ I++
Sbjct: 364 VIHPLDQPFTEKGGLAVLFGNLAPDGAIIKTGGVQNGITRHEGPAVVFDSQDEALDGIIN 423
Query: 418 GDIEKGDVVVIRYEGPKGGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIGH 477
+++GDVV+IRYEGPKGGPGM EMLAPTS I GMGL VAL+TDGRFSGA+RGLSIGH
Sbjct: 424 RKVKEGDVVIIRYEGPKGGPGMPEMLAPTSQIVGMGLGPKVALITDGRFSGASRGLSIGH 483
Query: 478 VSPEAAEGGPIALVEDGDLIRIDVKAKRIDLLVDEEELKERKAKWK---PKVKEVKGYLK 534
VSPEAAEGGP+A VE+GD I +D++ + +D+ V EEE ++RKA WK PKVK GYL
Sbjct: 484 VSPEAAEGGPLAFVENGDHIIVDIEKRILDVQVPEEEWEKRKANWKGFEPKVK--TGYLA 541
Query: 535 RYSSLVTSANTGAVFR 550
RYS LVTSANTG + +
Sbjct: 542 RYSKLVTSANTGGIMK 557
>pir||H69059 dihydroxy-acid dehydratase - Methanobacterium thermoautotrophicum
(strain Delta H) >gi|2622562|gb|AAB85924.1| (AE000906)
dihydroxy-acid dehydratase [Methanobacterium
thermoautotrophicum]
Length = 489
Score = 532 bits (1356), Expect = e-150
Identities = 274/490 (55%), Positives = 369/490 (74%), Gaps = 7/490 (1%)
Query: 64 SGGTPLEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCDKII 123
+GG EF+T+ ICDGIAM H GMKYSL SRE++AD++E++ A+ DG+V++ +CDKI+
Sbjct: 4 AGGVAFEFNTMAICDGIAMNHDGMKYSLASREIVADTVESMAMAHALDGLVLLPTCDKIV 63
Query: 124 PGMLMAMARLDIPAIFISGGPMLPGRFKGEYVDVKTVFEAVGAVKAGKMSEKELKLLEDF 183
PGMLMA ARLDIPAI ++GGPMLPG FKG VD+ V+E VG V AG+MSE EL+ LE
Sbjct: 64 PGMLMAAARLDIPAIVVTGGPMLPGEFKGRKVDLINVYEGVGTVSAGEMSEDELEELERC 123
Query: 184 ACPGCGSCAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKLVEEDL 243
ACPG SCAG+FTANTM LTEALG+SLP TA AV + + +IA+ +G +I+++V+E+L
Sbjct: 124 ACPGPRSCAGLFTANTMACLTEALGMSLPGCATAHAVSSRKRQIARLSGKRIVEMVQENL 183
Query: 244 KPSDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREA-GVKLTLDTFDEISEKTPTLVK 302
KP+ I++ EAFE+A+ VD+ALGGSTNT LH+ AIA E G+ + LD FDE+S P +
Sbjct: 184 KPTMIMSQEAFENAVMVDLALGGSTNTTLHIPAIAAEIDGLNINLDLFDELSRVIPHIAS 243
Query: 303 ISPAGKHFVLDLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVGELLRDVSVLRDDVIRP 362
ISPAG+H +LDL AGG+ A++K L + I+ + +T + +TV E + +V V DVIRP
Sbjct: 244 ISPAGEHMMLDLDRAGGIPAVLKTLED--HINRECVTCTGRTVQENIENVKVGHRDVIRP 301
Query: 363 VTRPYLSRGGLMILYGSLAPKGAVLKVSAI-PDIETFEGEARVFDCEEDAVKAILSGDIE 421
+ P S GGL IL G+LAP+G+V+K A+ D+ EG A+VF+ E++ ++AI G I+
Sbjct: 302 LDSPVHSEGGLAILRGNLAPRGSVVKQGAVAEDMMVHEGPAKVFNSEDECMEAIFGGRID 361
Query: 422 KGDVVVIRYEGPKGGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIGHVSPE 481
+GDV+VIRYEGPKGGPGMREML PTSAIAGMGL+R VAL+TDGRFSG TRG +GHVSPE
Sbjct: 362 EGDVIVIRYEGPKGGPGMREMLNPTSAIAGMGLER-VALITDGRFSGGTRGPCVGHVSPE 420
Query: 482 AAEGGPIALVEDGDLIRIDVKAKRIDLLVDEEELKER-KAKWKPKVKEVKGYLKRYSSLV 540
A E GP+A V DGD+IRID+ ++++++ + E++ER ++ KP+ + VKG+L RY L
Sbjct: 421 AMEDGPLAAVNDGDIIRIDIPSRKLEVDLSPREIEERLQSAVKPR-RSVKGWLARYRKLA 479
Query: 541 TSANTGAVFR 550
SA+TGAV R
Sbjct: 480 GSADTGAVLR 489
>pir||H81416 dihydroxy-acid dehydratase (EC 4.2.1.9) Cj0013 [imported] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6967518|emb|CAB72506.1| (AL139074) dihydroxy-acid
dehydratase [Campylobacter jejuni]
Length = 558
Score = 531 bits (1354), Expect = e-150
Identities = 276/554 (49%), Positives = 390/554 (69%), Gaps = 6/554 (1%)
Query: 1 MRSDVIKKGIERAPHRALFKAMGLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTG 60
MRSD IKKG RAP+R+L +A GL DE+ DKP IG+ NS+ ++IPGH L A+ +K
Sbjct: 1 MRSDAIKKGHLRAPNRSLLRACGLKDEDFDKPFIGVANSYIDIIPGHYFLNDYAKIIKDE 60
Query: 61 VRMSGGTPLEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCD 120
+R +G P EF+TIG+ DGIAMGH GM YSLPSRELIA+SIE V+ A+ D ++ I +CD
Sbjct: 61 IRKNGCVPFEFNTIGVDDGIAMGHEGMLYSLPSRELIANSIETVMNAHQLDALICIPNCD 120
Query: 121 KIIPGMLMAMARLDIPAIFISGGPMLPG-RFKGEYVDVKTVFEAVGAVKAGKMSEKELKL 179
KI PGMLM R+++P IF+SGGPM G KGE + + +VFEAVGA ++ K+SE+E K
Sbjct: 121 KITPGMLMGALRVNVPTIFVSGGPMASGVTKKGEKISLSSVFEAVGAYESKKISEEEFKD 180
Query: 180 LEDFACPGCGSCAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKL- 238
+E ACP GSC+GMFTAN+MN L EA+GI+L NGT A+ R + ++ +I ++
Sbjct: 181 IECSACPSGGSCSGMFTANSMNTLCEAMGIALEGNGTILALSKEREELLRKAARRICEIA 240
Query: 239 VEEDLKPSDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFDEISEKTP 298
++E K +I+T +A +A+ VDMA+GGS+NTVLH++AI+REAGV L + + IS K
Sbjct: 241 LDERFKIRNIITQKAVRNAMVVDMAMGGSSNTVLHMLAISREAGVALDIKDLNFISSKVA 300
Query: 299 TLVKISPA-GKHFVLDLYEAGGVLAIMKRLSELG--LIHEDRITVSLKTVGELLRDVSVL 355
+ KI+P+ ++ D+++AGGV A+M +S ++ D +T++ +++ E L++ +
Sbjct: 301 HIAKIAPSLNSVYMDDIHKAGGVSAVMAEISSRQGHILELDALTITGESLKERLKNAKIK 360
Query: 356 RDDVIRPVTRPYLSRGGLMILYGSLAPKGAVLKVSAIPDIETFEGEARVFDCEEDAVKAI 415
+++IR V Y GGL IL+G+LA +G V+K + I F+G+A F+ +++A+K I
Sbjct: 361 DENIIRKVDNAYSKVGGLAILFGNLAKQGCVIKTAGIIGERKFKGKAVCFNSQDEAIKGI 420
Query: 416 LSGDIEKGDVVVIRYEGPKGGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSI 475
+ G ++KG+V VIRYEGPKGGPGM+EML+PTS + GMGL DVAL+TDGRFSGATRGLS+
Sbjct: 421 IKGKVQKGNVCVIRYEGPKGGPGMQEMLSPTSLLMGMGLGADVALITDGRFSGATRGLSV 480
Query: 476 GHVSPEAAEGGPIALVEDGDLIRIDVKAKRIDLLVDEEELKERKAKWKPKVKEVKG-YLK 534
GH+SPEAAEGG I L++DGD I IDV A I V EEE+ +RK ++ KEV +L+
Sbjct: 481 GHISPEAAEGGLIGLLKDGDEIEIDVDAYTIHANVSEEEIAKRKKEFALPQKEVSSRWLR 540
Query: 535 RYSSLVTSANTGAV 548
Y LV++A+ GAV
Sbjct: 541 MYQKLVSNASKGAV 554
>gb|AAK43209.1| Dihydroxy-acid dehydratase (ilvD) [Sulfolobus solfataricus]
Length = 558
Score = 528 bits (1346), Expect = e-149
Identities = 274/546 (50%), Positives = 382/546 (69%), Gaps = 6/546 (1%)
Query: 9 GIERAPHRALFKAMGLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTGVRMSGGTP 68
GI APHRA +++GLTDEE+ KPL+ I +++E P + H +A K G + +G +P
Sbjct: 13 GIYNAPHRAFLRSVGLTDEEIGKPLVAIATAWSEAGPCNFHTLALARVAKEGTKEAGLSP 72
Query: 69 LEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCDKIIPGMLM 128
L F T+ + D I MG GM+YSL SR+LIAD +EA A+ FDG+V I CDK PG+LM
Sbjct: 73 LAFPTMVVNDNIGMGSEGMRYSLVSRDLIADMVEAQFNAHAFDGLVGIGGCDKTTPGILM 132
Query: 129 AMARLDIPAIFISGGPMLPGRFKGEYVDVKTVFEAVGAVKAGKMSEKELKLLEDFACPGC 188
AMARL++P+I+I GG PG F G+ + ++ V EA+GA A +++E EL +E A P
Sbjct: 133 AMARLNVPSIYIYGGSAEPGYFMGKRLTIEDVHEAIGAYLAKRITENELYEIEKRAHPTL 192
Query: 189 GSCAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKLVEEDLKPSDI 248
G+C+G+FTANTM +++EALG++LP + + A + R+ K+TG + L+E +K +I
Sbjct: 193 GTCSGLFTANTMGSMSEALGMALPGSASPTATSSRRVMYVKETGKALGSLIENGIKSREI 252
Query: 249 LTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFDEISEKTPTLVKISPAGK 308
LT EAFE+AI MA+GGSTN VLHL+AIA EAGVKLTLD F+ IS++TP + + P G
Sbjct: 253 LTFEAFENAITTLMAMGGSTNAVLHLLAIAYEAGVKLTLDDFNRISKRTPYIASMKPGGD 312
Query: 309 HFVLDLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVGELLRDV---SVLRDDVIRPVTR 365
+ + DL E GGV ++K+L + GL+H D +TV+ KT+ + L +V ++R V
Sbjct: 313 YVMADLDEVGGVPVVLKKLLDAGLLHGDVLTVTGKTMKQNLEQYKYPNVPHSHIVRDVKN 372
Query: 366 PYLSRGGLMILYGSLAPKGAVLKVSAIPDIETFEGEARVFDCEEDAVKAILSGDIEKGDV 425
P RGG++IL GSLAP+GAV+KV+A ++ FEG+A+V++ E+DA K + SG++ +G+V
Sbjct: 373 PIKPRGGIVILKGSLAPEGAVIKVAA-TNVVKFEGKAKVYNSEDDAFKGVQSGEVSEGEV 431
Query: 426 VVIRYEGPKGGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIGHVSPEAAEG 485
V+IRYEGPKG PGM EML T+AI G GL+ +VALVTDGRFSGATRG +GHV+PEA G
Sbjct: 432 VIIRYEGPKGAPGMPEMLRVTAAIMGAGLN-NVALVTDGRFSGATRGPMVGHVAPEAMVG 490
Query: 486 GPIALVEDGDLIRIDVKAKRIDLLVDEEELKERKAKWKPKVKEVK-GYLKRYSSLVTSAN 544
GPIA+VEDGD I IDV+++R+DL + EEE+K R +W P K G L +Y+SLV+ A+
Sbjct: 491 GPIAIVEDGDTIVIDVESERLDLKLSEEEIKNRLKRWSPPSPRYKSGLLAKYASLVSQAS 550
Query: 545 TGAVFR 550
GAV R
Sbjct: 551 MGAVTR 556
>sp|P74689|ILVD_SYNY3 DIHYDROXY-ACID DEHYDRATASE (DAD) >gi|7436855|pir||S76895
hypothetical protein - Synechocystis sp. (strain PCC
6803) >gi|1653897|dbj|BAA18807.1| (D90917) dihydroxyacid
dehydratase [Synechocystis sp.]
Length = 561
Score = 512 bits (1305), Expect = e-144
Identities = 263/551 (47%), Positives = 372/551 (66%), Gaps = 5/551 (0%)
Query: 2 RSDVIKKGIERAPHRALFKAMGLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTGV 61
RS VI +G +R+P+RA+ +A+G D++ KP++GI N ++ + P ++ + +A + G+
Sbjct: 6 RSQVITQGTQRSPNRAMLRAVGFGDDDFTKPIVGIANGYSTITPCNMGINDLALRAEAGL 65
Query: 62 RMSGGTPLEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCDK 121
R +G P F TI I DGI+MG GMKYSL SRE+IADSIE V DG++ I CDK
Sbjct: 66 RTAGAMPQLFGTITISDGISMGTEGMKYSLVSREVIADSIETVCNGQRMDGVLAIGGCDK 125
Query: 122 IIPGMLMAMARLDIPAIFISGGPMLPGRFKGEYVDVKTVFEAVGAVKAGKMSEKELKLLE 181
+PG ++AMARL+IP+IF+ GG + PG + GE + V + FEAVG AGK+ E+ L +E
Sbjct: 126 NMPGAMIAMARLNIPSIFVYGGTIKPGHYAGEDLTVVSAFEAVGQYSAGKIDEETLYGIE 185
Query: 182 DFACPGCGSCAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKLVEE 241
ACPG GSC GMFTANTM++ EA+G+SLP++ T AV + +++ +++ +++
Sbjct: 186 RNACPGAGSCGGMFTANTMSSAFEAMGMSLPYSSTMAAVDGEKADSTEESAKVLVEAIKK 245
Query: 242 DLKPSDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFDEISEKTPTLV 301
+ PS ILT +AFE+AIAV MA+GGSTN VLHL+AIA GV L+LD F+ I K P L
Sbjct: 246 QILPSQILTRKAFENAIAVIMAVGGSTNAVLHLLAIANTIGVPLSLDDFETIRHKVPVLC 305
Query: 302 KISPAGKHFVLDLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVGELLRDV---SVLRDD 358
+ P+GK+ +L+ AGG+ +MK L G++H D +T++ +T+ E+L D+ D
Sbjct: 306 DLKPSGKYVTTNLHAAGGIPQVMKILLVNGILHGDALTITGQTIAEVLADIPDQPPAGQD 365
Query: 359 VIRPVTRPYLSRGGLMILYGSLAPKGAVLKVSAIPDIETFEGEARVFDCEEDAVKAILSG 418
VI P G L +L G+LA +G+V K+S + G A+VF+ EED ++AIL+G
Sbjct: 366 VIHSWDDPVYQEGHLAVLKGNLATEGSVAKISGVKK-PVITGPAKVFESEEDCLEAILAG 424
Query: 419 DIEKGDVVVIRYEGPKGGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIGHV 478
I+ GDVVV+RYEGPKGGPGMREMLAPTSAI G GL V L+TDGRFSG T GL +GHV
Sbjct: 425 KIQAGDVVVVRYEGPKGGPGMREMLAPTSAIIGAGLGDSVGLITDGRFSGGTYGLVVGHV 484
Query: 479 SPEAAEGGPIALVEDGDLIRIDVKAKRIDLLVDEEELKERKAKW-KPKVKEVKGYLKRYS 537
+PEA GG IALV++GD I ID + + L + EEEL +R+A+W P+ + +G L +Y+
Sbjct: 485 APEAYVGGAIALVQEGDQITIDAGKRLLQLNISEEELAQRRAQWTPPQPRYPRGILAKYA 544
Query: 538 SLVTSANTGAV 548
LV+S++ GAV
Sbjct: 545 KLVSSSSLGAV 555
>sp|O07433|ILVD_MYCTU DIHYDROXY-ACID DEHYDRATASE (DAD) >gi|7436856|pir||H70906 probable
ilvD protein - Mycobacterium tuberculosis (strain H37RV)
>gi|2213526|emb|CAB09740.1| (Z97050) ilvD [Mycobacterium
tuberculosis]
Length = 575
Score = 512 bits (1304), Expect = e-144
Identities = 275/555 (49%), Positives = 364/555 (65%), Gaps = 9/555 (1%)
Query: 2 RSDVIKKGIERAPHRALFKAMGLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTGV 61
RS + G+E+A R + +A+G+ DE+ KP IG+ +S+NE+ P ++ L R+A AVK GV
Sbjct: 20 RSRDVTDGLEKAAARGMLRAVGMDDEDFAKPQIGVASSWNEITPCNLSLDRLANAVKEGV 79
Query: 62 RMSGGTPLEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCDK 121
+GG PLEF TI + DGI+MGH GM +SL SRE+IADS+E V++A DG V++A CDK
Sbjct: 80 FSAGGYPLEFGTISVSDGISMGHEGMHFSLVSREVIADSVEVVMQAERLDGSVLLAGCDK 139
Query: 122 IIPGMLMAMARLDIPAIFISGGPMLPGRFK---GEYVDVKTV--FEAVGAVKAGKMSEKE 176
+PGMLMA ARLD+ A+F+ G +LPGR K G DV + FEAVGA G MS +
Sbjct: 140 SLPGMLMAAARLDLAAVFLYAGSILPGRAKLSDGSERDVTIIDAFEAVGACSRGLMSRAD 199
Query: 177 LKLLEDFACPGCGSCAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIM 236
+ +E CPG G+C GM+TANTM + EALG+SLP + PA R A+++G ++
Sbjct: 200 VDAIERAICPGEGACGGMYTANTMASAAEALGMSLPGSAAPPATDRRRDGFARRSGQAVV 259
Query: 237 KLVEEDLKPSDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFDEISEK 296
+L+ + DILT EAFE+AIAV MA GGSTN VLHL+AIA EA V L+L F I
Sbjct: 260 ELLRRGITARDILTKEAFENAIAVVMAFGGSTNAVLHLLAIAHEANVALSLQDFSRIGSG 319
Query: 297 TPTLVKISPAGKHFVLDLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVGELLRDVSVLR 356
P L + P G+H + D+ GGV +MK L + GL+H D +TV+ T+ E L ++
Sbjct: 320 VPHLADVKPFGRHVMSDVDHIGGVPVVMKALLDAGLLHGDCLTVTGHTMAENLAAITPPD 379
Query: 357 DD--VIRPVTRPYLSRGGLMILYGSLAPKGAVLKVSAIPDIETFEGEARVFDCEEDAVKA 414
D V+R + P GG+ IL+GSLAP+GAV+K + D + FEG ARVFD E A+ A
Sbjct: 380 PDGKVLRALANPIHPSGGITILHGSLAPEGAVVKTAGF-DSDVFEGTARVFDGERAALDA 438
Query: 415 ILSGDIEKGDVVVIRYEGPKGGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLS 474
+ G I GD VVIRYEGPKGGPGMREMLA T AI G GL +DV L+TDGRFSG T GL
Sbjct: 439 LEDGTITVGDAVVIRYEGPKGGPGMREMLAITGAIKGAGLGKDVLLLTDGRFSGGTTGLC 498
Query: 475 IGHVSPEAAEGGPIALVEDGDLIRIDVKAKRIDLLVDEEELKERKAKWK-PKVKEVKGYL 533
+GH++PEA +GGPIAL+ +GD IR+DV + +D+L D E R+ + P + G L
Sbjct: 499 VGHIAPEAVDGGPIALLRNGDRIRLDVAGRVLDVLADPAEFASRQQDFSPPPPRYTTGVL 558
Query: 534 KRYSSLVTSANTGAV 548
+Y LV+SA GAV
Sbjct: 559 SKYVKLVSSAAVGAV 573
>sp|O06069|ILVD_MYCLE DIHYDROXY-ACID DEHYDRATASE (DAD) >gi|2104594|emb|CAB08798.1|
(Z95398) IlvD [Mycobacterium leprae]
Length = 564
Score = 506 bits (1288), Expect = e-142
Identities = 270/555 (48%), Positives = 361/555 (64%), Gaps = 9/555 (1%)
Query: 2 RSDVIKKGIERAPHRALFKAMGLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTGV 61
RS + G+E+A R + +A+G+ D++ K IG+ +S+NE+ P ++ L R+A+AVK GV
Sbjct: 9 RSRDVTDGLEKAAARGMLRAVGMNDDDFAKAQIGVASSWNEITPCNLSLDRLAKAVKEGV 68
Query: 62 RMSGGTPLEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCDK 121
+GG PLEF TI + DGI+MGH GM +SL SRE+IADS+E V++A DG V++A CDK
Sbjct: 69 FSAGGYPLEFGTISVSDGISMGHQGMHFSLVSREVIADSVETVMQAERLDGSVLLAGCDK 128
Query: 122 IIPGMLMAMARLDIPAIFISGGPMLPGRFK-----GEYVDVKTVFEAVGAVKAGKMSEKE 176
+PGMLMA ARLD+ ++F+ G +LPGR K V + FEAVGA G M +
Sbjct: 129 SLPGMLMAAARLDLASVFLYAGSILPGRTKLSDGTEHEVTLIDAFEAVGACSRGLMPRAD 188
Query: 177 LKLLEDFACPGCGSCAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIM 236
+ +E CPG G+C GM+TANTM + EALG+SLP + PA R A+++G ++
Sbjct: 189 VDAIERAICPGEGACGGMYTANTMASAAEALGMSLPGSAAPPATDRRRDGFARRSGQAVI 248
Query: 237 KLVEEDLKPSDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFDEISEK 296
+L+ + DILT EAFE+AIAV MA GGSTN +LHL+AIA EA V L+L+ F I K
Sbjct: 249 ELLRRGITARDILTKEAFENAIAVVMAFGGSTNAILHLLAIAHEADVTLSLEDFSRIGFK 308
Query: 297 TPTLVKISPAGKHFVLDLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVGELLRDVSVLR 356
P + + P G+H + D+ GGV +MK L + GL+H D +TV+ +T+ E L ++
Sbjct: 309 VPHIADVKPFGRHVMFDVDHIGGVPVVMKALLDAGLLHGDCLTVTGQTMAENLASIAPPD 368
Query: 357 DD--VIRPVTRPYLSRGGLMILYGSLAPKGAVLKVSAIPDIETFEGEARVFDCEEDAVKA 414
D VIR + P GG+ IL GSLAP GAV+K + + D + FEG ARVFD E A+ A
Sbjct: 369 PDGQVIRTLHNPIHPTGGITILRGSLAPDGAVVKTAGL-DSDVFEGTARVFDGERAALDA 427
Query: 415 ILSGDIEKGDVVVIRYEGPKGGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLS 474
+ G I KGDVVVIRYEGPKGGPGMREMLA T AI G GL +DV L+TDGRFSG T G
Sbjct: 428 LKDGTIAKGDVVVIRYEGPKGGPGMREMLAITGAIKGAGLGKDVLLLTDGRFSGGTTGFC 487
Query: 475 IGHVSPEAAEGGPIALVEDGDLIRIDVKAKRIDLLVDEEELKERKAKW-KPKVKEVKGYL 533
+GH++PEA E GPIA + DGD + +DV +D+LVD E RK + P + G L
Sbjct: 488 VGHIAPEAVEAGPIAFLRDGDRVLLDVVGCSLDVLVDPVEFSSRKKDFIPPAPRYTTGVL 547
Query: 534 KRYSSLVTSANTGAV 548
+Y LV+SA GAV
Sbjct: 548 AKYVKLVSSATVGAV 562
>sp|Q9YG88|ILVD_AERPE DIHYDROXY-ACID DEHYDRATASE (DAD) >gi|7436860|pir||H72752 probable
dihydroxy-acid dehydratase APE0013 - Aeropyrum pernix
(strain K1) >gi|5103401|dbj|BAA78922.1| (AP000058) 575aa
long hypothetical dihydroxy-acid dehydratase [Aeropyrum
pernix]
Length = 575
Score = 497 bits (1265), Expect = e-139
Identities = 272/548 (49%), Positives = 360/548 (65%), Gaps = 2/548 (0%)
Query: 2 RSDVIKKGIERAPHRALFKAMGLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTGV 61
RS + G+E PHR +A+G T ++ KPLI +V +++E P + ++ + VK GV
Sbjct: 27 RSRLWYDGLENTPHRVYLRAIGFTSDDFQKPLIAVVAAWSEAGPCNFNVLPGSLRVKEGV 86
Query: 62 RMSGGTPLEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCDK 121
R +GG PL TI + DGI MG GM+YSL SRELIAD+IEA V ++ FDG V I CDK
Sbjct: 87 RSAGGVPLAVPTIVVNDGINMGTPGMRYSLISRELIADTIEAQVASHGFDGWVGIGGCDK 146
Query: 122 IIPGMLMAMARLDIPAIFISGGPMLPGRFKGEYVDVKTVFEAVGAVKAGKMSEKELKLLE 181
PG++MAMARLD+P+I+I GG G GE V V++ FEAVGA G + E+ L +E
Sbjct: 147 TQPGIMMAMARLDLPSIYIYGGTAEHGVLDGETVTVQSAFEAVGAYLKGLIDEERLYEIE 206
Query: 182 DFACPGCGSCAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKLVEE 241
A P G+C G+FTANTM L EALG+S + + PA + R R + G + LVE
Sbjct: 207 KAAMPTPGTCQGLFTANTMAILAEALGLSPLGSASPPATSSERARELARAGALAVGLVET 266
Query: 242 DLKPSDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFDEISEKTPTLV 301
L P ILT EAF +AI MA+ GSTN VLHL+AIAREAGVKL LD FDE S K P +
Sbjct: 267 GLTPRRILTYEAFYNAIVTLMAISGSTNAVLHLLAIAREAGVKLALDDFDEASRKVPVIA 326
Query: 302 KISPAGKHFVLDLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVGELLRDVSVLRD-DVI 360
++PAGK+ ++DL+ GG I+++L + GL++ + +TV +G+LL D +++
Sbjct: 327 ALAPAGKYTMVDLHNVGGAPVILRKLLDRGLLYGEAVTVEGVEIGKLLSKWEPRTDYNIL 386
Query: 361 RPVTRPYLSRGGLMILYGSLAPKGAVLKVSAIPDIETFEGEARVFDCEEDAVKAILSGDI 420
+PY GL IL GSLAP+GAV+K+ A I F+G A+VFD EE+A KAI G +
Sbjct: 387 YDFDKPYKPHAGLRILRGSLAPRGAVMKIGA-SGILKFKGAAKVFDSEEEAFKAIERGYV 445
Query: 421 EKGDVVVIRYEGPKGGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIGHVSP 480
E+GDVVV+RY GPKG PGM EML T+AI G GL VAL+TDGRFSGATRG+ +GH +P
Sbjct: 446 EEGDVVVVRYVGPKGAPGMPEMLKITAAIVGAGLGEKVALITDGRFSGATRGVMVGHAAP 505
Query: 481 EAAEGGPIALVEDGDLIRIDVKAKRIDLLVDEEELKERKAKWKPKVKEVKGYLKRYSSLV 540
EAA GGPIALVE+GD I ID + +D+L+ +EL R+ KW P +G L++Y+ LV
Sbjct: 506 EAAVGGPIALVENGDEIVIDGEKGTLDVLLGGDELARRRDKWSPPPLPKQGLLRKYAKLV 565
Query: 541 TSANTGAV 548
T A+ GAV
Sbjct: 566 TQADEGAV 573
>pir||C75432 dihydroxy-acid dehydratase - Deinococcus radiodurans (strain R1)
>gi|6458870|gb|AAF10706.1|AE001963_1 (AE001963)
dihydroxy-acid dehydratase [Deinococcus radiodurans]
Length = 607
Score = 488 bits (1242), Expect = e-137
Identities = 263/600 (43%), Positives = 376/600 (61%), Gaps = 53/600 (8%)
Query: 2 RSDVIKKGIERAPHRALFKAMGLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTGV 61
RS +G A RAL++A G+TD + KP+I +VNSF + +PGH+HL+ + + V +
Sbjct: 5 RSRTTTEGRNMAGARALWRATGMTDGDFQKPIIAVVNSFTQFVPGHVHLKDLGQLVAGEI 64
Query: 62 RMSGGTPLEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCDK 121
+GG EF+TI + DGIAMGH GM YSLPSRE+IADS+E +V A+ D +V I++CDK
Sbjct: 65 AAAGGVAKEFNTIAVDDGIAMGHDGMLYSLPSREIIADSVEYMVNAHCADAMVCISNCDK 124
Query: 122 IIPGMLMAMARLDIPAIFISGGPMLPGRFK-GEYVDVKTVFEAVGAVKAGKMSEKELKLL 180
I PGMLMA RL+IP +F+SGGPM G+ K G+ + +A+ +SE++++L+
Sbjct: 125 ITPGMLMAALRLNIPTVFVSGGPMEAGKVKLGDGEHALDLVDAMVMAADDSVSEEDIELV 184
Query: 181 EDFACPGCGSCAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKLV- 239
E ACP CGSC+GMFTAN+MN LTEALG+SLP NG+ A ++ R + K+ G I+ L
Sbjct: 185 ERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSVLATHSDRQNLFKRAGHLIVDLAK 244
Query: 240 ------EEDLKPSDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFDEI 293
+E + P + T +AFE+A+ +D+++GGSTNTVLHL+A A EAGV T+ D++
Sbjct: 245 RYYEGDDESVLPRSVATYDAFENAMTLDISMGGSTNTVLHLLAAAHEAGVDFTMQDIDQL 304
Query: 294 SEKTPTLVKISPAGKHFVL-DLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVGELLRDV 352
S + P L K++PA + D++ AGG++ I+ L GL+ D TV ++ L +
Sbjct: 305 SRRVPVLCKVAPAKNDVHMEDVHRAGGIMGILGELDRAGLLKTDVSTVHAPSMSAALNEW 364
Query: 353 SVLRDD-----------------------------------VIRPVTRPYLSRGGLMILY 377
V+R++ VIR + GGL +LY
Sbjct: 365 DVVRNENHHEFYRAAPGGIPTVFAFSQSRRYRELDTDREAGVIRSAEHAFSQDGGLAVLY 424
Query: 378 GSLAPKGAVLKVSAIPD-IETFEGEARVFDCEEDAVKAILSGDIEKGDVVVIRYEGPKGG 436
G+LA G ++K + + + I F G ARVF+ ++ +V AILSG++++G+VV+IRYEGP+GG
Sbjct: 425 GNLAEDGCIVKTAGVDESILKFSGPARVFESQDASVDAILSGEVKEGEVVLIRYEGPRGG 484
Query: 437 PGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIGHVSPEAAEGGPIALVEDGDL 496
PGM+EML PTS + GL + ALVTDGRFSG + GLSIGHVSPEAAEGG I LVE GDL
Sbjct: 485 PGMQEMLYPTSYLKSKGLGKACALVTDGRFSGGSSGLSIGHVSPEAAEGGTIGLVETGDL 544
Query: 497 IRIDVKAKRIDLLVDEEELKERKAK-----W---KPKVKEVKGYLKRYSSLVTSANTGAV 548
I ID+ + I L V + EL R+ K W +P+ +++ L+ Y+S+ TSA+ GAV
Sbjct: 545 IEIDIPNRTIHLAVPDAELAARRQKREEEGWHPAEPRPRKITAALRAYASMTTSASRGAV 604
>sp|P05791|ILVD_ECOLI DIHYDROXY-ACID DEHYDRATASE (DAD) >gi|68303|pir||DWECDA
dihydroxy-acid dehydratase (EC 4.2.1.9) - Escherichia
coli >gi|146461|gb|AAB59053.1| (M10313) dihydroxyacid
dehydrase [Escherichia coli] >gi|288532|emb|CAA28576.1|
(X04890) dihydroxy acid [Escherichia coli]
>gi|225742|prf||1312306A gene ilvGMEDA cluster
[Escherichia coli]
Length = 616
Score = 484 bits (1233), Expect = e-136
Identities = 275/606 (45%), Positives = 372/606 (61%), Gaps = 61/606 (10%)
Query: 2 RSDVIKKGIERAPHRALFKAMGLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTGV 61
RS G A RAL++A G+TD + KP+I +VNSF + +PGH+HLR + + V +
Sbjct: 5 RSATTTHGRNMAGARALWRATGMTDADFGKPIIAVVNSFTQFVPGHVHLRDLGKLVAEQI 64
Query: 62 RMSGGTPLEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCDK 121
+GG EF+TI + DGIAMGHGGM YSLPSRELIADS+E +V A+ D +V I++CDK
Sbjct: 65 EAAGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDK 124
Query: 122 IIPGMLMAMARLDIPAIFISGGPMLPGRFKGEYVDVKTVFEAVGAVKAG---KMSEKELK 178
I PGMLMA RL+IP IF+SGGPM G+ K +K + V A+ G K+S+ +
Sbjct: 125 ITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDQIIK--LDLVDAMIQGADPKVSDSQSD 182
Query: 179 LLEDFACPGCGSCAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKL 238
+E ACP CGSC+GMFTAN+MN LTEALG+S P NG+ A +A R ++ G +I++L
Sbjct: 183 QVERSACPTCGSCSGMFTANSMNCLTEALGLSQPGNGSLLATHADRKQLFLNAGKRIVEL 242
Query: 239 V-------EEDLKPSDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFD 291
+E P +I + AFE+A+ +D+A+GGSTNTVLHL+A A+EA + T+ D
Sbjct: 243 TKRYYEQNDESALPRNIASKAAFENAMTLDIAMGGSTNTVLHLLAAAQEAEIDFTMSDID 302
Query: 292 EISEKTPTLVKISPA-GKHFVLDLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVGELLR 350
++S K P L K++P+ K+ + D++ AGGV+ I+ L GL++ D V T+ + L
Sbjct: 303 KLSRKVPQLCKVAPSTQKYHMEDVHRAGGVIGILGELDRAGLLNRDVKNVLGLTLPQTLE 362
Query: 351 --DVSVLRDDV-----------------------------------IRPVTRPYLSRGGL 373
DV + +DD IR + Y GGL
Sbjct: 363 QYDVMLTQDDAVKNMFRAGPAGIRTTQAFSQDCRWDTLDDDRANGCIRSLEHAYSKDGGL 422
Query: 374 MILYGSLAPKGAVLKVSAIPD-IETFEGEARVFDCEEDAVKAILSGDIEKGDVVVIRYEG 432
+LYG+ A G ++K + + D I F G A+V++ ++DAV+AIL G + GDVVVIRYEG
Sbjct: 423 AVLYGNFAENGCIVKTAGVDDSILKFTGPAKVYESQDDAVEAILGGKVVAGDVVVIRYEG 482
Query: 433 PKGGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIGHVSPEAAEGGPIALVE 492
PKGGPGM+EML PTS + MGL + AL+TDGRFSG T GLSIGHVSPEAA GG I L+E
Sbjct: 483 PKGGPGMQEMLYPTSFLKSMGLGKACALITDGRFSGGTSGLSIGHVSPEAASGGSIGLIE 542
Query: 493 DGDLIRIDVKAKRIDLLVDEEELKERK--------AKWKPKVKE--VKGYLKRYSSLVTS 542
DGDLI ID+ + I L V + EL R+ W PK +E V L+ Y+SL TS
Sbjct: 543 DGDLIAIDIPNRGIQLQVSDAELAARREAQDARGDKAWTPKNRERQVSFALRAYASLATS 602
Query: 543 ANTGAV 548
A+ GAV
Sbjct: 603 ADKGAV 608
>gb|AAF33480.1| (AF233324) S typhimurium dihydroxy-acid dehydratase (ILVD)
(SP:P40810); contains similarity to Pfam family PF00920
(Dehydratase family), score=1023.9, E=3.5e-304, N=1
[Salmonella typhimurium LT2]
Length = 616
Score = 484 bits (1232), Expect = e-135
Identities = 272/606 (44%), Positives = 375/606 (60%), Gaps = 61/606 (10%)
Query: 2 RSDVIKKGIERAPHRALFKAMGLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTGV 61
RS G A RAL++A G+TD + KP+I +VNSF + +PGH+HLR + + V +
Sbjct: 5 RSATTTHGRNMAGARALWRATGMTDSDFGKPIIAVVNSFTQFVPGHVHLRDLGKLVAEQI 64
Query: 62 RMSGGTPLEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCDK 121
SGG EF+TI + DGIAMGHGGM YSLPSRELIADS+E +V A+ D +V I++CDK
Sbjct: 65 EASGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDK 124
Query: 122 IIPGMLMAMARLDIPAIFISGGPMLPGRFKGEYVDVKTVFEAVGAVKAG---KMSEKELK 178
I PGMLMA RL+IP IF+SGGPM G+ K +K + V A+ G K+S+ +
Sbjct: 125 ITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDKIIK--LDLVDAMIQGADPKVSDDQSN 182
Query: 179 LLEDFACPGCGSCAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKL 238
+E ACP CGSC+GMFTAN+MN LTEALG+S P NG+ A +A R ++ G +I++L
Sbjct: 183 QVERSACPTCGSCSGMFTANSMNCLTEALGLSQPGNGSLLATHADRKQLFLNAGKRIVEL 242
Query: 239 V-------EEDLKPSDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFD 291
+E P +I + AFE+A+ +D+A+GGSTNTVLHL+A A+EA + T+ D
Sbjct: 243 TKRYYEQNDESALPRNIASKAAFENAMTLDIAMGGSTNTVLHLLAAAQEAEIDFTMSDID 302
Query: 292 EISEKTPTLVKISPA-GKHFVLDLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVGELLR 350
++S K P L K++P+ K+ + D++ AGGVL I+ L GL++ + V T+ + L
Sbjct: 303 KLSRKVPQLCKVAPSTQKYHMEDVHRAGGVLGILGELDRAGLLNRNVKNVLGLTLPQTLE 362
Query: 351 --DVSVLRDDVIRPVTR-----------------------------------PYLSRGGL 373
D++V +D+ ++ + R Y GGL
Sbjct: 363 QYDITVTQDEAVKKMFRAGPAGIRTTQAFSQDCRWDSLDDDRAAGCIRSLEYAYSKDGGL 422
Query: 374 MILYGSLAPKGAVLKVSAIPD-IETFEGEARVFDCEEDAVKAILSGDIEKGDVVVIRYEG 432
+LYG+ A G ++K + + D I F G A+V++ ++DAV+AIL G + +GDVVVIRYEG
Sbjct: 423 AVLYGNFAENGCIVKTAGVDDSILKFTGPAKVYESQDDAVEAILGGKVVEGDVVVIRYEG 482
Query: 433 PKGGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIGHVSPEAAEGGPIALVE 492
PKGGPGM+EML PTS + MGL + AL+TDGRFSG T GLSIGHVSPEAA GG IAL+E
Sbjct: 483 PKGGPGMQEMLYPTSFLKSMGLGKACALITDGRFSGGTSGLSIGHVSPEAASGGTIALIE 542
Query: 493 DGDLIRIDVKAKRIDLLVDEEELKERK--------AKWKPK--VKEVKGYLKRYSSLVTS 542
DGD I ID+ + I L + E E+ R+ W PK ++V L+ Y+SL TS
Sbjct: 543 DGDTIAIDIPNRSIQLQLSEAEIAARREAQEARGDKAWTPKNRQRQVSFALRAYASLATS 602
Query: 543 ANTGAV 548
A+ GAV
Sbjct: 603 ADKGAV 608
>pir||C83601 dihydroxy-acid dehydratase PA0353 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9946203|gb|AAG03742.1|AE004473_4 (AE004473)
dihydroxy-acid dehydratase [Pseudomonas aeruginosa]
Length = 612
Score = 475 bits (1209), Expect = e-133
Identities = 262/601 (43%), Positives = 369/601 (60%), Gaps = 55/601 (9%)
Query: 2 RSDVIKKGIERAPHRALFKAMGLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTGV 61
RS G A RAL++A G+ DE+ KP+I I NSF + +PGH+HL+ + + V +
Sbjct: 5 RSKTSTHGRNMAGARALWRATGMKDEDFKKPIIAIANSFTQFVPGHVHLKDLGQLVAREI 64
Query: 62 RMSGGTPLEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCDK 121
+GG EF+TI + DGIAMGH GM YSLPSRE+IADS+E +V A+ D IV I++CDK
Sbjct: 65 EKAGGVAKEFNTIAVDDGIAMGHDGMLYSLPSREIIADSVEYMVNAHCADAIVCISNCDK 124
Query: 122 IIPGMLMAMARLDIPAIFISGGPMLPGRFKGEYVDVKTVFEAVGAVKAGKMSEKELKLLE 181
I PGMLMA RL+IP +F+SGGPM G+ K + V +A+ S++++ E
Sbjct: 125 ITPGMLMAALRLNIPVVFVSGGPMEAGKTKLASHGLDLV-DAMVVAADDSCSDEKVAEYE 183
Query: 182 DFACPGCGSCAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKLV-- 239
ACP CGSC+GMFTAN+MN LTEALG+SLP NG+ A +A R ++ + G ++L
Sbjct: 184 RSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSTLATHADREQLFLRAGRLAVELCQR 243
Query: 240 -----EEDLKPSDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFDEIS 294
++ + P +I +AFE+A+ +D+A+GGSTNT+LHL+A A+EA V L D +S
Sbjct: 244 YYGEGDDSVLPRNIANFKAFENAMTLDIAMGGSTNTILHLLAAAQEAEVPFDLRDIDRLS 303
Query: 295 EKTPTLVKISP-AGKHFVLDLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVGELLR--D 351
K P L K++P K+ + D++ AGG+ +I+ L+ GL+H D TV ++ + + D
Sbjct: 304 RKVPQLCKVAPNIQKYHMEDVHRAGGIFSILGELARGGLLHTDVPTVHSPSMADAIAQWD 363
Query: 352 VSVLRDDV-----------------------------------IRPVTRPYLSRGGLMIL 376
++ RD+ IR V Y GGL +L
Sbjct: 364 ITQTRDEAVHTFFKAGPAGIPTQTAFSQNTRWPSLDDDRAEGCIRSVEHAYSKEGGLAVL 423
Query: 377 YGSLAPKGAVLKVSAIPD-IETFEGEARVFDCEEDAVKAILSGDIEKGDVVVIRYEGPKG 435
YG++A G V+K + + + I FEG A++F+ ++ AVK IL +++ GD+V+IRYEGPKG
Sbjct: 424 YGNIALDGCVVKTAGVDESIHVFEGSAKIFESQDAAVKGILGDEVKAGDIVIIRYEGPKG 483
Query: 436 GPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIGHVSPEAAEGGPIALVEDGD 495
GPGM+EML PTS + GL + AL+TDGRFSG T GLSIGH SPEAA GG I LV+DGD
Sbjct: 484 GPGMQEMLYPTSYLKSKGLGKQCALLTDGRFSGGTSGLSIGHASPEAAAGGAIGLVQDGD 543
Query: 496 LIRIDVKAKRIDLLVDEEELKERKAK-----WK---PKVKEVKGYLKRYSSLVTSANTGA 547
+ ID+ + I+LLV +EEL R+A+ WK P+ + V LK Y+ L TSA+ GA
Sbjct: 544 KVLIDIPNRSINLLVSDEELAARRAEQDKKGWKPAAPRARRVSTALKAYALLATSADKGA 603
Query: 548 V 548
V
Sbjct: 604 V 604
>sp|P44851|ILVD_HAEIN DIHYDROXY-ACID DEHYDRATASE (DAD) >gi|1074007|pir||G64089
dihydroxy-acid dehydratase (EC 4.2.1.9) - Haemophilus
influenzae (strain Rd KW20) >gi|1573744|gb|AAC22397.1|
(U32757) dihydroxyacid dehydratase (ilvD) [Haemophilus
influenzae Rd]
Length = 612
Score = 474 bits (1208), Expect = e-133
Identities = 264/602 (43%), Positives = 373/602 (61%), Gaps = 54/602 (8%)
Query: 1 MRSDVIKKGIERAPHRALFKAMGLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTG 60
+RS +G A RAL++A G+ + + KP+I +VNSF + +PGH+HL+ + + V
Sbjct: 4 LRSATSTQGRNMAGARALWRATGMKENDFGKPIIAVVNSFTQFVPGHVHLKDMGQLVAAE 63
Query: 61 VRMSGGTPLEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCD 120
+ +GG EF+TI + DGIAMGHGGM YSLPSR+LIADS+E +V A+ D +V I++CD
Sbjct: 64 IEKAGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRDLIADSVEYMVNAHCADAMVCISNCD 123
Query: 121 KIIPGMLMAMARLDIPAIFISGGPMLPGRFK-GEYVDVKTVFEAVGAVKAGKMSEKELKL 179
KI PGMLMA RL+IP IF+SGGPM G+ K + + + +A+ +S++ +
Sbjct: 124 KITPGMLMAAMRLNIPTIFVSGGPMEAGKTKLSDQLIRLDLVDAMIEAADPNVSDERIDA 183
Query: 180 LEDFACPGCGSCAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKL- 238
+E ACP CGSC+GMFTAN+MN LTEALG+SLP NG+ A +A R + + G QI++L
Sbjct: 184 IERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSMLATHADRKELFLKAGRQIVELC 243
Query: 239 ---VEED---LKPSDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFDE 292
E+D + P I T +AFE+A+++D+A+GGS+NTVLHL+A A+EAGV ++ D
Sbjct: 244 KRYYEQDDASVLPRSIGTFDAFENAMSLDIAMGGSSNTVLHLLAAAQEAGVDFKMEDIDR 303
Query: 293 ISEKTPTLVKISP-AGKHFVLDLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVGELLRD 351
+S K P L KI+P K+ + D++ AGG++ ++ L GLIH++ TV ++GE L
Sbjct: 304 LSRKVPCLSKIAPNTNKYHMEDVHRAGGIMGLLGELDRAGLIHKNTHTVLGMSMGEQLDQ 363
Query: 352 VSVLRDD-------------------------------------VIRPVTRPYLSRGGLM 374
++R+ IR GGL
Sbjct: 364 YDIIRNQDEELHKFFRAGPAGIRTTQAFSQDCRWDTVDNDRVNGCIRNKENAISQEGGLA 423
Query: 375 ILYGSLAPKGAVLKVSAIPD-IETFEGEARVFDCEEDAVKAILSGDIEKGDVVVIRYEGP 433
+L+G+LA G ++K + + + I F G A VF+ +EDAV IL G +++G VVVIRYEGP
Sbjct: 424 VLFGNLAEDGCIVKTAGVDESIWKFTGTAIVFESQEDAVAGILGGKVKEGHVVVIRYEGP 483
Query: 434 KGGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIGHVSPEAAEGGPIALVED 493
KGGPGM+EML PTS + MGL + AL+TDGRFSG T GLSIGHVSPEAA GG I LV +
Sbjct: 484 KGGPGMQEMLYPTSYLKSMGLGKKCALLTDGRFSGGTSGLSIGHVSPEAASGGAIGLVRN 543
Query: 494 GDLIRIDVKAKRIDLLVDEEELKERKAK-----WKP--KVKEVKGYLKRYSSLVTSANTG 546
GD+I ID+ + I+L + EEL R+A+ W+P + +EV LK + TSA+ G
Sbjct: 544 GDIINIDIPNRAINLEISNEELATRRAEQDQKGWQPANREREVSFALKVFGHFATSADKG 603
Query: 547 AV 548
AV
Sbjct: 604 AV 605
>gb|AAC77491.1| (AE000453) dihydroxyacid dehydratase [Escherichia coli K12]
Length = 605
Score = 474 bits (1208), Expect = e-133
Identities = 267/585 (45%), Positives = 362/585 (61%), Gaps = 61/585 (10%)
Query: 23 GLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTGVRMSGGTPLEFSTIGICDGIAM 82
G+TD + KP+I +VNSF + +PGH+HLR + + V + +GG EF+TI + DGIAM
Sbjct: 15 GMTDADFGKPIIAVVNSFTQFVPGHVHLRDLGKLVAEQIEAAGGVAKEFNTIAVDDGIAM 74
Query: 83 GHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCDKIIPGMLMAMARLDIPAIFISG 142
GHGGM YSLPSRELIADS+E +V A+ D +V I++CDKI PGMLMA RL+IP IF+SG
Sbjct: 75 GHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGMLMASLRLNIPVIFVSG 134
Query: 143 GPMLPGRFKGEYVDVKTVFEAVGAVKAG---KMSEKELKLLEDFACPGCGSCAGMFTANT 199
GPM G+ K +K + V A+ G K+S+ + +E ACP CGSC+GMFTAN+
Sbjct: 135 GPMEAGKTKLSDQIIK--LDLVDAMIQGADPKVSDSQSDQVERSACPTCGSCSGMFTANS 192
Query: 200 MNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKLV-------EEDLKPSDILTPE 252
MN LTEALG+S P NG+ A +A R ++ G +I++L +E P +I +
Sbjct: 193 MNCLTEALGLSQPGNGSLLATHADRKQLFLNAGKRIVELTKRYYEQNDESALPRNIASKA 252
Query: 253 AFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFDEISEKTPTLVKISPA-GKHFV 311
AFE+A+ +D+A+GGSTNTVLHL+A A+EA + T+ D++S K P L K++P+ K+ +
Sbjct: 253 AFENAMTLDIAMGGSTNTVLHLLAAAQEAEIDFTMSDIDKLSRKVPQLCKVAPSTQKYHM 312
Query: 312 LDLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVGELLR--DVSVLRDDV---------- 359
D++ AGGV+ I+ L GL++ D V T+ + L DV + +DD
Sbjct: 313 EDVHRAGGVIGILGELDRAGLLNRDVKNVLGLTLPQTLEQYDVMLTQDDAVKNMFRAGPA 372
Query: 360 -------------------------IRPVTRPYLSRGGLMILYGSLAPKGAVLKVSAIPD 394
IR + Y GGL +LYG+ A G ++K + + D
Sbjct: 373 GIRTTQAFSQDCRWDTLDDDRANGCIRSLEHAYSKDGGLAVLYGNFAENGCIVKTAGVDD 432
Query: 395 -IETFEGEARVFDCEEDAVKAILSGDIEKGDVVVIRYEGPKGGPGMREMLAPTSAIAGMG 453
I F G A+V++ ++DAV+AIL G + GDVVVIRYEGPKGGPGM+EML PTS + MG
Sbjct: 433 SILKFTGPAKVYESQDDAVEAILGGKVVAGDVVVIRYEGPKGGPGMQEMLYPTSFLKSMG 492
Query: 454 LDRDVALVTDGRFSGATRGLSIGHVSPEAAEGGPIALVEDGDLIRIDVKAKRIDLLVDEE 513
L + AL+TDGRFSG T GLSIGHVSPEAA GG I L+EDGDLI ID+ + I L V +
Sbjct: 493 LGKACALITDGRFSGGTSGLSIGHVSPEAASGGSIGLIEDGDLIAIDIPNRGIQLQVSDA 552
Query: 514 ELKERK--------AKWKPKVKE--VKGYLKRYSSLVTSANTGAV 548
EL R+ W PK +E V L+ Y+SL TSA+ GAV
Sbjct: 553 ELAARREAQDARGDKAWTPKNRERQVSFALRAYASLATSADKGAV 597
>pir||A82850 dihydroxy-acid dehydratase XF0099 [imported] - Xylella fastidiosa
(strain 9a5c) >gi|9104877|gb|AAF82912.1|AE003863_14
(AE003863) dihydroxy-acid dehydratase [Xylella
fastidiosa]
Length = 610
Score = 474 bits (1208), Expect = e-133
Identities = 265/602 (44%), Positives = 363/602 (60%), Gaps = 57/602 (9%)
Query: 2 RSDVIKKGIERAPHRALFKAMGLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTGV 61
RS G A RAL++A G+ D++ KP+I I NSF + +PGH+HL+ + + V +
Sbjct: 5 RSKTSTYGRNMAGARALWRATGMKDDDFQKPIIAIANSFTQFVPGHVHLKDLGQLVAREI 64
Query: 62 RMSGGTPLEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCDK 121
GG EF+TI + DGIAMGH GM YSLPSRE+IADS+E + A+ D +V I++CDK
Sbjct: 65 ERLGGVAKEFNTIAVDDGIAMGHDGMLYSLPSREIIADSVEYMANAHCADALVCISNCDK 124
Query: 122 IIPGMLMAMARLDIPAIFISGGPMLPGRFKGEYVDVK-TVFEAVGAVKAGKMSEKELKLL 180
I PGMLMA RL+IP +F+SGGPM G+ K D K + +A+ S++E+ +
Sbjct: 125 ITPGMLMASLRLNIPTVFVSGGPMEAGKTK--LTDHKLDLVDAMVLAADPHASDEEVAAV 182
Query: 181 EDFACPGCGSCAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKLV- 239
E ACP CGSC+GMFTAN+MN LTEALG+SLP NGT A ++ R ++ G +++L
Sbjct: 183 ERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGTVVATHSDRKQLFLNAGRTVIELCH 242
Query: 240 ----EEDLK--PSDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFDEI 293
ED P I T AFE+AI +D+A+GGSTNT+LHL+A A+EA V T+ D +
Sbjct: 243 RWYGNEDATALPRGIATFAAFENAITLDIAMGGSTNTILHLLAAAQEAEVPFTMQDIDRL 302
Query: 294 SEKTPTLVKISP-AGKHFVLDLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVGELLR-- 350
S P L K++P K+ + D++ AGG+ I+ L+ L+H D TV KT+GE +
Sbjct: 303 SRNVPQLCKVAPNTQKYHIEDVHRAGGIFGILAELARGNLLHTDVATVHSKTLGEAIATW 362
Query: 351 DVSVLRDDV-----------------------------------IRPVTRPYLSRGGLMI 375
D+ +D+ IR + + GGL +
Sbjct: 363 DIIGTQDEAVHTFYKAGPAGISTQVAFSQSTRWPSLDTDRTEGCIRDMEHAFSKEGGLAV 422
Query: 376 LYGSLAPKGAVLKVSAI-PDIETFEGEARVFDCEEDAVKAILSGDIEKGDVVVIRYEGPK 434
LYG++A G V+K + + I FEG A V++ +E AVK ILS +++ G +VVIRYEGPK
Sbjct: 423 LYGNIAQDGCVVKTAGVDASIHVFEGSALVYESQEAAVKGILSDEVQPGMIVVIRYEGPK 482
Query: 435 GGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIGHVSPEAAEGGPIALVEDG 494
GGPGM+EML PTS + GL + AL TDGRFSG T GLSIGH SPEAA GG I L+ DG
Sbjct: 483 GGPGMQEMLYPTSYLKSKGLGKQCALFTDGRFSGGTSGLSIGHASPEAAAGGAIGLIRDG 542
Query: 495 DLIRIDVKAKRIDLLVDEEELKERKAK-----WKP---KVKEVKGYLKRYSSLVTSANTG 546
D IRID+ + I++L+ EEEL R+ + WKP + ++V LK Y+ L TSA+ G
Sbjct: 543 DRIRIDIPQRAINVLISEEELASRRLEQHAIGWKPAQSRTRKVSSALKAYALLATSADKG 602
Query: 547 AV 548
AV
Sbjct: 603 AV 604
>gb|AAA67574.1| (M87049) dihydroxyacid dehydratase [Escherichia coli]
Length = 605
Score = 473 bits (1204), Expect = e-132
Identities = 266/585 (45%), Positives = 361/585 (61%), Gaps = 61/585 (10%)
Query: 23 GLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTGVRMSGGTPLEFSTIGICDGIAM 82
G+TD + KP+I +VNSF + +PGH+HLR + + V + +GG EF+TI + DGIAM
Sbjct: 15 GMTDADFGKPIIAVVNSFTQFVPGHVHLRDLGKLVAEQIEAAGGVAKEFNTIAVDDGIAM 74
Query: 83 GHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCDKIIPGMLMAMARLDIPAIFISG 142
GHGGM YSLPSRELIADS+E +V A+ D +V I++CDKI PGMLMA RL+IP IF+SG
Sbjct: 75 GHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGMLMASLRLNIPVIFVSG 134
Query: 143 GPMLPGRFKGEYVDVKTVFEAVGAVKAG---KMSEKELKLLEDFACPGCGSCAGMFTANT 199
GPM G+ K +K + V A+ G K+S+ + +E ACP CGSC+GMFTAN+
Sbjct: 135 GPMEAGKTKLSDQIIK--LDLVDAMIQGADPKVSDSQSDQVERSACPTCGSCSGMFTANS 192
Query: 200 MNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKLV-------EEDLKPSDILTPE 252
MN LTEALG+S P NG+ A +A R ++ G +I++L +E P +I +
Sbjct: 193 MNCLTEALGLSQPGNGSLLATHADRKQLFLNAGKRIVELTKRYYEQNDESALPRNIASKA 252
Query: 253 AFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFDEISEKTPTLVKISPA-GKHFV 311
FE+A+ +D+A+GGSTNTVLHL+A A+EA + T+ D++S K P L K++P+ K+ +
Sbjct: 253 XFENAMTLDIAMGGSTNTVLHLLAAAQEAEIDFTMSDIDKLSRKVPQLCKVAPSTQKYHM 312
Query: 312 LDLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVGELLR--DVSVLRDDV---------- 359
D++ AGGV+ I+ L GL++ D V T+ + L DV + +DD
Sbjct: 313 EDVHRAGGVIGILGELDRAGLLNRDVKNVLGLTLPQTLEQYDVMLTQDDAVKNMFRAGPA 372
Query: 360 -------------------------IRPVTRPYLSRGGLMILYGSLAPKGAVLKVSAIPD 394
IR + Y GGL +LYG+ A G ++K + + D
Sbjct: 373 GIRTTQAFSQDCRWDTLDDDRANGCIRSLEHAYSKDGGLAVLYGNFAENGCIVKTAGVDD 432
Query: 395 -IETFEGEARVFDCEEDAVKAILSGDIEKGDVVVIRYEGPKGGPGMREMLAPTSAIAGMG 453
I F G A+V++ ++DAV+AIL G + GDVVVIRYEGPKGGPGM+EML PTS + MG
Sbjct: 433 SILKFTGPAKVYESQDDAVEAILGGKVVAGDVVVIRYEGPKGGPGMQEMLYPTSFLKSMG 492
Query: 454 LDRDVALVTDGRFSGATRGLSIGHVSPEAAEGGPIALVEDGDLIRIDVKAKRIDLLVDEE 513
L + AL+TDGRFSG T GLSIGHVSPEAA GG I L+EDGDLI ID+ + I L V +
Sbjct: 493 LGKACALITDGRFSGGTSGLSIGHVSPEAASGGSIGLIEDGDLIAIDIPNRGIQLQVSDA 552
Query: 514 ELKERK--------AKWKPKVKE--VKGYLKRYSSLVTSANTGAV 548
EL R+ W PK +E V L+ Y+SL TSA+ GAV
Sbjct: 553 ELAARREAQDARGDKAWTPKNRERQVSFALRAYASLATSADKGAV 597
>gb|AAG10494.1|AF279106_56 (AF279106) predicted dihydroxyacid dehydratase [uncultured
proteobacterium EBAC31A08]
Length = 532
Score = 471 bits (1200), Expect = e-132
Identities = 250/534 (46%), Positives = 345/534 (63%), Gaps = 7/534 (1%)
Query: 18 LFKAMGLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTGVRMSGGTPLEFSTIGIC 77
+ + +G T E KP +GI ++ ++ P ++H+ ++E V+ V SGG + F+TI +
Sbjct: 1 MLRGVGFTSEXFTKPFVGIASTGAKVTPCNMHINALSEIVEKSVDSSGGKGVLFNTITVS 60
Query: 78 DGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCDKIIPGMLMAMARLDIPA 137
DGI+MG GMKYSL SRE+IADSIE VV +DG++ + CDK +PG ++ MARL+ P+
Sbjct: 61 DGISMGTQGMKYSLVSREVIADSIETVVGCLGYDGVIAVGGCDKNMPGCIIGMARLNRPS 120
Query: 138 IFISGGPMLPGRFKGEYVDVKTVFEAVGAVKAGKMSEKELKLLEDFACPGCGSCAGMFTA 197
IFI GG + P + +YV TV E G G + E EL +E + G GSC GM+TA
Sbjct: 121 IFIYGGSIKPSKENTDYV---TVCEKTGEYSKGDLKESELIHVEKISVKGPGSCGGMYTA 177
Query: 198 NTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKLVEEDLKPSDILTPEAFEDA 257
NTM + EALG+SLP + + A+ + + G IM L+E+D+KPSDI+T AFE+A
Sbjct: 178 NTMASAIEALGMSLPGSSSQDAISHDKEDDCFKAGEAIMNLLEKDIKPSDIMTKNAFENA 237
Query: 258 IAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFDEISEKTPTLVKISPAGKHFVLDLYEA 317
I + +ALGGSTN VLHL+A+A GV L LD F I +KTP + + P G H++ +L
Sbjct: 238 ITMVIALGGSTNAVLHLLAMAHSIGVDLELDDFTRIGKKTPVMADLKPFGSHYMSELNAN 297
Query: 318 GGVLAIMKRLSELGLIHEDRITVSLKTVGELLRDVSVLRDD--VIRPVTRPYLSRGGLMI 375
GG+ +MK L E GL+H + +TV+ +T+ E L + D +I+ P S L I
Sbjct: 298 GGIQPLMKTLLEKGLLHGNCLTVTGQTLAENLSGIKPYEPDQEIIKSFDNPIKSNSHLRI 357
Query: 376 LYGSLAPKGAVLKVSAIPDIETFEGEARVFDCEEDAVKAILSGDIEKGDVVVIRYEGPKG 435
LYG+LA GAV K++ + +FEG ARVFD EE+ VKAILS I+ GDVVVIRYEGPKG
Sbjct: 358 LYGNLAKDGAVAKITG-KEGTSFEGSARVFDSEEEGVKAILSKSIKAGDVVVIRYEGPKG 416
Query: 436 GPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIGHVSPEAAEGGPIALVEDGD 495
GPGMREML PTSAI G GL VA +TDGRFSG T G +GH++PEAA+GG IA+++DGD
Sbjct: 417 GPGMREMLKPTSAIMGQGLGDQVAFITDGRFSGGTHGFVVGHITPEAADGGLIAIIKDGD 476
Query: 496 LIRIDVKAKRIDLLVDEEELKERKAKW-KPKVKEVKGYLKRYSSLVTSANTGAV 548
I ID + ++ L + E+E+ R ++W PK KG L +++ V SA+ GAV
Sbjct: 477 SILIDADSDKLILNISEDEISNRLSRWVNPKTPPKKGVLAKFAKSVKSASLGAV 530
>gb|AAF13798.1|AF130812_2 (AF130812) dihydroxy acid dehydratase [Buchnera aphidicola]
Length = 617
Score = 469 bits (1194), Expect = e-131
Identities = 254/592 (42%), Positives = 366/592 (60%), Gaps = 61/592 (10%)
Query: 16 RALFKAMGLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTGVRMSGGTPLEFSTIG 75
R+L++A G+ DE+ KP+I IVNSF++ +PGHIHL+++ E + ++ SGG P EF+TI
Sbjct: 19 RSLWRATGMNDEDFKKPIIAIVNSFSQFVPGHIHLKKVGELISDQIQKSGGVPKEFNTIA 78
Query: 76 ICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCDKIIPGMLMAMARLDI 135
I DGIAMGH GM YSLPSRELIADSIE V+ A+ D ++ +++CDKI PGMLMA RL+I
Sbjct: 79 IDDGIAMGHSGMLYSLPSRELIADSIEYVINAHCVDAMICVSNCDKITPGMLMAALRLNI 138
Query: 136 PAIFISGGPMLPGRFKGEYVDVKTVFEAVGAVKAGKMS---EKELKLLEDFACPGCGSCA 192
P++FISGGPM G+ + ++K + V A+ G S + +K +E ACP CGSC+
Sbjct: 139 PSVFISGGPMEAGKIRKNEKEIK--IDLVDAIMIGGQSNQCKNFIKEVELLACPTCGSCS 196
Query: 193 GMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKLVEE-------DLKP 245
GMFTAN+MN LTEA+G+SLP NGT A + R + ++ I+K+ +E + P
Sbjct: 197 GMFTANSMNCLTEAIGLSLPGNGTLLATHVDRKNLFIKSAKTIVKITKEYYHHNNKKVLP 256
Query: 246 SDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFDEISEKTPTLVKISP 305
I + E+FE+A+ +D+A+GGSTNT+LHL+A A+EA + + DE+S K P + K+SP
Sbjct: 257 RSIASKESFENAMILDIAMGGSTNTILHLLAAAQEAEIDFNMSNIDELSRKIPHICKVSP 316
Query: 306 A-GKHFVLDLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVGELLRDVSVL--------- 355
+ + + D++ AGGV+ I+ L+ L+++ + + E L++ ++
Sbjct: 317 STSLYHMEDVHRAGGVMGILGELNRANLLNKQTQNILQLNLEETLKEYDIVLSKNPDILK 376
Query: 356 ----------------------------RDDVIRPVTRPYLSRGGLMILYGSLAPKGAVL 387
+ IR Y GGL +LYG+LA G ++
Sbjct: 377 MFKAKPAGIRTIQPYSQENRWLTLDYDRKTGCIRSCKNAYSQDGGLAVLYGNLAKNGCII 436
Query: 388 KVSAIPDIE-TFEGEARVFDCEEDAVKAILSGDIEKGDVVVIRYEGPKGGPGMREMLAPT 446
K + I F G ARV++ +E+AV AIL G+I GD+VVIRYEGPKGGPGM+EML PT
Sbjct: 437 KTAGIKKSNYIFSGPARVYESQEEAVNAILKGEIISGDIVVIRYEGPKGGPGMQEMLYPT 496
Query: 447 SAIAGMGLDRDVALVTDGRFSGATRGLSIGHVSPEAAEGGPIALVEDGDLIRIDVKAKRI 506
+ + M LD+ AL+TDGRFSG T GLSIGHVSPEAA G IALV++GD+I ID+ + I
Sbjct: 497 TYLKSMKLDKTCALITDGRFSGGTSGLSIGHVSPEAANKGVIALVKNGDIINIDITQRVI 556
Query: 507 DLLVDEEELKER--------KAKWKP--KVKEVKGYLKRYSSLVTSANTGAV 548
+L + E+EL++R +KP + + + LK Y+ SA+ GAV
Sbjct: 557 NLNITEQELQQRIFQEESKKSLSYKPLNRKRHISYALKTYAFFAMSADKGAV 608
>pir||E81117 dihydroxy-acid dehydratase NMB1150, NMB1188 [imported] - Neisseria
meningitidis (group B strain MD58)
>gi|7226387|gb|AAF41537.1| (AE002463) dihydroxy-acid
dehydratase [Neisseria meningitidis MC58]
>gi|7226425|gb|AAF41572.1| (AE002466) dihydroxy-acid
dehydratase [Neisseria meningitidis MC58]
Length = 619
Score = 465 bits (1183), Expect = e-130
Identities = 255/607 (42%), Positives = 362/607 (59%), Gaps = 60/607 (9%)
Query: 2 RSDVIKKGIERAPHRALFKAMGLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTGV 61
RS G A RAL++A G+ + + KP+I + NSF + +PGH+HL + + V +
Sbjct: 5 RSKTSTHGRNMAGARALWRATGVMETDFGKPIIAVANSFTQFVPGHVHLHNMGQLVAREI 64
Query: 62 RMSGGTPLEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCDK 121
+G EF+TI I DGIAMGH GM YSLPSR+LIADSIE +V A+ D +V I++CDK
Sbjct: 65 EKAGAIAKEFNTIAIDDGIAMGHSGMLYSLPSRDLIADSIEYMVNAHCADALVCISNCDK 124
Query: 122 IIPGMLMAMARLDIPAIFISGGPMLPGRFKG-EYVDVKTVFEAVGAV---KAGKMSEKEL 177
I PGML+A RL+IP IF+SGGPM G+ G + + + + A+ +S +++
Sbjct: 125 ITPGMLIAAMRLNIPTIFVSGGPMEAGKVIGVANIQPERRLDLIDAMIESADDNVSNRQV 184
Query: 178 KLLEDFACPGCGSCAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMK 237
+ +E ACP CGSC+GMFTAN+MN LTEALG+SLP NG+ A +A R + + G I++
Sbjct: 185 EEVEQNACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSYLATHAGRKELFLEAGRMIVE 244
Query: 238 LV-------EEDLKPSDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTF 290
+ +E + P I T +AFE+A+ +D+A+GGSTNT+LHL+A+A EAGV +
Sbjct: 245 ITKRYYEQNDETVLPRSIATKKAFENAMTMDIAMGGSTNTILHLLAVANEAGVDFKMADI 304
Query: 291 DEISEKTPTLVKISPAG-KHFVLDLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVGELL 349
D +S P + K +P +++ D++ AGG+ AI+K L + G +H D T+ T+ + +
Sbjct: 305 DRLSRVVPCICKTAPNNHDYYMEDVHRAGGIFAILKELDKAGKLHTDVHTIHAPTLKDAI 364
Query: 350 RDVSVLRDD-------------------------------------VIRPVTRPYLSRGG 372
V + IR V Y GG
Sbjct: 365 EQWDVTNPENTRAIERFKAAPGGVRTTQAFSQNRMWKTLDLDREKGCIRDVAHAYSQDGG 424
Query: 373 LMILYGSLAPKGAVLKVSAIPD-IETFEGEARVFDCEEDAVKAILSGDIEKGDVVVIRYE 431
L +L+G++A +G V+K + + + I F G ARVF+ +EDAV+ IL I GD+V+IRYE
Sbjct: 425 LAVLFGNIAERGCVVKTAGVDESILKFTGRARVFESQEDAVEGILGNQIVAGDIVIIRYE 484
Query: 432 GPKGGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIGHVSPEAAEGGPIALV 491
GPKGGPGM+EML PTS + GL + AL+TDGRFSG T GLSIGH SPEAAEGG I LV
Sbjct: 485 GPKGGPGMQEMLYPTSYLKSKGLGKACALLTDGRFSGGTSGLSIGHASPEAAEGGAIGLV 544
Query: 492 EDGDLIRIDVKAKRIDLLVDEEELKERKAK--------WKPKVKE--VKGYLKRYSSLVT 541
+GD + ID+ + I L + +EEL R+A+ WKPK ++ V L+ Y ++ T
Sbjct: 545 HEGDTVEIDIPNRSIHLAISDEELAARRAEMEARGSKAWKPKNRDRYVSAALRAYGAMAT 604
Query: 542 SANTGAV 548
SA+ GAV
Sbjct: 605 SADKGAV 611
>pir||F82374 dihydroxy-acid dehydratase VC0028 [imported] - Vibrio cholerae
(group O1 strain N16961) >gi|9654420|gb|AAF93206.1|
(AE004094) dihydroxy-acid dehydratase [Vibrio cholerae]
Length = 613
Score = 464 bits (1180), Expect = e-129
Identities = 270/603 (44%), Positives = 367/603 (60%), Gaps = 58/603 (9%)
Query: 2 RSDVIKKGIERAPHRALFKAMGLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTGV 61
RS G A RAL++A G+ +E+ KP+I +VNSF + +PGH+HL+ + + V +
Sbjct: 5 RSATTTHGRNMAGARALWRATGVKEEDFGKPIIAVVNSFTQFVPGHVHLKDLGQLVAREI 64
Query: 62 RMSGGTPLEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCDK 121
+GG EF+TI + DGIAMGHGGM YSLPSRELIADS+E +V A+ D +V I++CDK
Sbjct: 65 EAAGGIAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDK 124
Query: 122 IIPGMLMAMARLDIPAIFISGGPMLPGRFKGEYVDVKTVFEAVGAVKAG---KMSEKELK 178
I PGMLMA RL+IPAIF+SGGPM G+ K +K + V A+ G K+S+ + +
Sbjct: 125 ITPGMLMAAMRLNIPAIFVSGGPMEAGKTKLSDQIIK--LDLVDAMMQGADPKVSDAQSE 182
Query: 179 LLEDFACPGCGSCAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKL 238
+E ACP CGSC+GMFTAN+MN LTEALG+S P NG+ A +A R ++ G +I++L
Sbjct: 183 QIERSACPTCGSCSGMFTANSMNCLTEALGLSQPGNGSLLATHADRKQLFLTAGQRIVEL 242
Query: 239 V----EED---LKPSDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFD 291
E+D + P +I AFE+AIA+D+A+GGSTNTVLHL+A A+E V+ + D
Sbjct: 243 TKRYYEQDDASVLPRNIANKAAFENAIALDIAMGGSTNTVLHLLAAAQEGEVEFDMTDID 302
Query: 292 EISEKTPTLVKISPA-GKHFVLDLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVGELLR 350
+S + P L K++P+ K+ + D++ AGGV+ I+ L GL+ + TV ++ E L
Sbjct: 303 RMSRQVPHLCKVAPSTQKYHMEDVHRAGGVMGILGELQRAGLLKDQTRTVLGISLQEQLA 362
Query: 351 DVSV---------------------------------LRDD----VIRPVTRPYLSRGGL 373
V L DD IR + GGL
Sbjct: 363 QYDVKQTQDPAVHTMFRAGPAGIRTTQAFSQDCRWDTLDDDRQEGCIRDKAHAFSQDGGL 422
Query: 374 MILYGSLAPKGAVLKVSAIPD-IETFEGEARVFDCEEDAVKAILSGDIEKGDVVVIRYEG 432
+L G+LA G ++K + + + I F G A V++ +EDAV IL G ++ GDVVVIRYEG
Sbjct: 423 AVLKGNLAIDGCIVKTAGVDESILKFRGPAVVYESQEDAVNGILGGQVKAGDVVVIRYEG 482
Query: 433 PKGGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIGHVSPEAAEGGPIALVE 492
PKGGPGM+EML PT+ + MGL + AL+TDGRFSG T GLSIGH SPEAA GG I LV
Sbjct: 483 PKGGPGMQEMLYPTTYLKSMGLGKQCALLTDGRFSGGTSGLSIGHASPEAANGGTIGLVR 542
Query: 493 DGDLIRIDVKAKRIDLLVDEEELKERKAK-----WKP--KVKEVKGYLKRYSSLVTSANT 545
GD I ID+ + I L V E EL R+A+ WKP + + V LK Y+S+ TSA+
Sbjct: 543 SGDSIAIDIPNRSITLEVSESELAARRAEQDKLGWKPVDRQRTVSLALKAYASMATSADK 602
Query: 546 GAV 548
GAV
Sbjct: 603 GAV 605
>gb|AAA24023.1| (M32253) ilvD [Escherichia coli]
Length = 615
Score = 462 bits (1175), Expect = e-129
Identities = 267/605 (44%), Positives = 366/605 (60%), Gaps = 60/605 (9%)
Query: 2 RSDVIKKGIERAPHRALFKAMGLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTGV 61
RS G A RAL++A G+TD + KP+I +VNSF + +PGH+HLR + + V +
Sbjct: 5 RSATTTHGRNMAGARALWRATGMTDADFGKPIIAVVNSFTQFVPGHVHLRDLGKLVAEQI 64
Query: 62 RMSGGTPLEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCDK 121
+GG EF+TI + DGIAMGHGGM YSLPSRELIADS+E +V A+ D +V I++CDK
Sbjct: 65 EAAGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDK 124
Query: 122 IIPGMLMAMARLDIPAIFISGGPMLPGRFKGEYVDVKTVFEAVGAVKAG---KMSEKELK 178
I PGMLMA RL+IP IF+SGGPM G+ K +K + V A+ G K+S+ +
Sbjct: 125 ITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDQIIK--LDPVDAMIQGADPKVSDSQSD 182
Query: 179 LLEDFACPGCGSCAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKL 238
+E ACP CGSC+GMFTAN+MN LTEALG+S P NG+ A +A R ++ G +I++L
Sbjct: 183 QVERSACPTCGSCSGMFTANSMNCLTEALGLSQPGNGSLLATHADRKQLFLNAGKRIVEL 242
Query: 239 V-------EEDLKPSDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFD 291
+E P +I + AFE+A+ +D+A+GGSTNTVLHL+A A+EA + T+ D
Sbjct: 243 TKRYYEQNDESALPRNIASKAAFENAMTLDIAMGGSTNTVLHLLAAAQEAEIDFTMSDID 302
Query: 292 EISEKTPTLVKISPA-GKHFVLDLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVGELLR 350
++S K P L K++P+ K+ + D++ AGGV+ I+ L GL++ D V T+ + L
Sbjct: 303 KLSRKVPQLCKVAPSTQKYHMEDVHRAGGVIGILGELDRAGLLNRDVKNVLGLTLPQTLE 362
Query: 351 --DVSVLRDDVIRPVTRPYLS---------------------RGGLMILYGSLAPKGAVL 387
DV + +DD ++ + R + G+ + + K A
Sbjct: 363 QYDVMLTQDDAVKNMFRAGPAGIRTTQAFSQDCRWDTLDDDRANGVSARWNTPTAKTAAW 422
Query: 388 KVSAI--------------PDIETFEGEARVFDCEEDAVKAILSGDIEKGDVVVIRYEGP 433
+ S + I F G A+V++ ++DAV+AIL G + GDVVVIRYEGP
Sbjct: 423 RCSTVILRKRLHRETAGVDDSILKFTGPAKVYESQDDAVEAILGGKVVAGDVVVIRYEGP 482
Query: 434 KGGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIGHVSPEAAEGGPIALVED 493
KGGPGM+EML PTS + MGL + AL+TDGRFSG T GLSIGHVSPEAA GG I L+ED
Sbjct: 483 KGGPGMQEMLYPTSFLKSMGLGKACALITDGRFSGGTSGLSIGHVSPEAASGGSIGLIED 542
Query: 494 GDLIRIDVKAKRIDLLVDEEELKERK--------AKWKPKVKE--VKGYLKRYSSLVTSA 543
GDLI ID+ + I L V + EL R+ W PK +E V L+ Y+SL TSA
Sbjct: 543 GDLIAIDIPNRGIQLQVSDAELAARREAQDARGDKAWTPKNRERQVSFALRAYASLATSA 602
Query: 544 NTGAV 548
+ GAV
Sbjct: 603 DKGAV 607
>sp|O69198|ILVD_STRCO DIHYDROXY-ACID DEHYDRATASE (DAD) >gi|3192889|gb|AAC35795.1|
(AF068843) dihydroxy-acid dehydratase [Streptomyces
coelicolor]
Length = 617
Score = 462 bits (1175), Expect = e-129
Identities = 265/607 (43%), Positives = 370/607 (60%), Gaps = 59/607 (9%)
Query: 1 MRSDVIKKGIERAPHRALFKAMGLTDEELD-KPLIGIVNSFNELIPGHIHLRRIAEAVKT 59
+RS + G A RAL +A G+ ++ KP+I + NSF E +PGH HL + V
Sbjct: 4 LRSRTVTHGRNMAGARALMRASGVPGADIGRKPIIAVANSFTEFVPGHTHLAPVGRIVSE 63
Query: 60 GVRMSGGTPLEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASC 119
V +GG P EF+TI + DGIAMGHGGM YSLPSR+LIADS+E +V A+ D ++ I++C
Sbjct: 64 AVTAAGGIPREFNTIAVDDGIAMGHGGMLYSLPSRDLIADSVEYMVEAHCADALICISNC 123
Query: 120 DKIIPGMLMAMARLDIPAIFISGGPMLPGRFKGEYVDVKT--VFEAVGAVKAGKMSEKEL 177
DKI PGML A RL+IP +F+SGGPM GR V+T + +A+ K+S+ ++
Sbjct: 124 DKITPGMLNAALRLNIPTVFVSGGPMESGRATLVDGTVRTLDLVDAMSEAVNDKISDADI 183
Query: 178 KLLEDFACPGCGSCAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMK 237
+E+ ACP CGSC+GMFTAN+MN LTEA+G+SLP NG+ A + R + + ++
Sbjct: 184 LRIEENACPTCGSCSGMFTANSMNCLTEAIGLSLPGNGSVLATHTARKTLYENAARTVLD 243
Query: 238 LV-------EEDLKPSDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTF 290
L ++ + P +I TP AF +A+A+D+A+GGSTNT+LHL+A A+EA V L
Sbjct: 244 LTRRYYEQDDDSVLPRNIATPAAFGNAMALDIAMGGSTNTILHLLASAQEAEVSYGLAEM 303
Query: 291 DEISEKTPTLVKISP----AGKHFVLDLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVG 346
D +S P L K++P +++ D++ AGG+ A++ L GL++ED +V ++
Sbjct: 304 DALSRSVPCLAKVAPNVAKDRTYYMEDVHRAGGIPALLGELHHGGLLNEDVHSVHSPSLA 363
Query: 347 ELLRDVSV----------------------------------LRDDV----IRPVTRPYL 368
+ L+ V L +D IR V Y
Sbjct: 364 DWLKTWDVRGGSPSKEAVELWHAAPGCVRSAEAFSQSERWDTLDEDAEGGCIRSVEHAYS 423
Query: 369 SRGGLMILYGSLAPKGAVLKVSAIPD-IETFEGEARVFDCEEDAVKAILSGDIEKGDVVV 427
GGL +L G+LA G V+K + + + I TFEG A V + +E+AV+ IL+ +++GDVVV
Sbjct: 424 KDGGLAVLRGNLAVDGCVVKTAGVDESIWTFEGPAVVCESQEEAVQKILTQQVKEGDVVV 483
Query: 428 IRYEGPKGGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIGHVSPEAAEGGP 487
IRYEGPKGGPGM+EML PTS + G GL + ALVTDGRFSG T GLSIGH SPEAA GG
Sbjct: 484 IRYEGPKGGPGMQEMLYPTSYLKGRGLGKACALVTDGRFSGGTSGLSIGHASPEAAAGGT 543
Query: 488 IALVEDGDLIRIDVKAKRIDLLVDEEELKERK----AKWKPKVKEVKGY--LKRYSSLVT 541
IALVEDGD IRID+ + I+LLVD+ EL R+ + PK ++ K + LK Y+++ T
Sbjct: 544 IALVEDGDRIRIDIPNRSIELLVDDAELTRREQALNGVYAPKNRDRKXFAELKAYAAMAT 603
Query: 542 SANTGAV 548
SA+ GAV
Sbjct: 604 SADKGAV 610
>pir||C81905 probable dihydroxy-acid dehydratase (EC 4.2.1.9) NMA1361 [imported]
- Neisseria meningitidis (group A strain Z2491)
>gi|7380029|emb|CAB84607.1| (AL162755) putative
dihydroxy-acid dehydratase [Neisseria meningitidis
Z2491]
Length = 619
Score = 462 bits (1175), Expect = e-129
Identities = 253/607 (41%), Positives = 362/607 (58%), Gaps = 60/607 (9%)
Query: 2 RSDVIKKGIERAPHRALFKAMGLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTGV 61
RS G A RAL++A G+ + + KP+I + NSF + +PGH+HL + + V +
Sbjct: 5 RSKTSTHGRNMAGARALWRATGVMETDFGKPIIAVANSFTQFVPGHVHLHNMGQLVAREI 64
Query: 62 RMSGGTPLEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCDK 121
+G EF+TI I DGIAMGH GM YSLPSR+LIADSIE +V A+ D +V I++CDK
Sbjct: 65 EKAGAIAKEFNTIAIDDGIAMGHSGMLYSLPSRDLIADSIEYMVNAHCADALVCISNCDK 124
Query: 122 IIPGMLMAMARLDIPAIFISGGPMLPGRFKG-EYVDVKTVFEAVGAV---KAGKMSEKEL 177
I PGML+A RL+IP IF+SGGPM G+ G + + + + A+ +S +++
Sbjct: 125 ITPGMLIAAMRLNIPTIFVSGGPMEAGKVIGVANIQPERRLDLIDAMIESADDNISNRQV 184
Query: 178 KLLEDFACPGCGSCAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMK 237
+ +E ACP CGSC+GMFTAN+MN LTEALG+SLP NG+ A + R + + G I++
Sbjct: 185 EEVEQNACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSYLATHVGRKELFLEAGRMIVE 244
Query: 238 LV-------EEDLKPSDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTF 290
+ +E + P I T +AFE+A+ +D+A+GGSTNT+LHL+A+A EAGV +
Sbjct: 245 ITKRYYEQNDETVLPRSIATKKAFENAMTMDIAMGGSTNTILHLLAVANEAGVDFKMADI 304
Query: 291 DEISEKTPTLVKISPAG-KHFVLDLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVGELL 349
D +S P + K +P +++ D++ AGG+ AI+K L + G +H D T+ T+ + +
Sbjct: 305 DRLSRVVPCICKTAPNNHDYYMEDVHRAGGIFAILKELDKAGKLHTDVHTIHAPTLKDAI 364
Query: 350 RDVSVLRDD-------------------------------------VIRPVTRPYLSRGG 372
V + IR V Y GG
Sbjct: 365 EKWDVTNPENTHAIERFKAAPGGVRTTQAFSQNRMWKTLDLDREKGCIRDVAHAYSQDGG 424
Query: 373 LMILYGSLAPKGAVLKVSAIPD-IETFEGEARVFDCEEDAVKAILSGDIEKGDVVVIRYE 431
L +L+G++A +G V+K + + + I F G ARVF+ +EDAV+ IL I GD+V+IRYE
Sbjct: 425 LAVLFGNIAERGCVVKTAGVDESILKFTGRARVFESQEDAVEGILGNQIVAGDIVIIRYE 484
Query: 432 GPKGGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIGHVSPEAAEGGPIALV 491
GPKGGPGM+EML PTS + GL + AL+TDGRFSG T GLSIGH SPEAAEGG I LV
Sbjct: 485 GPKGGPGMQEMLYPTSYLKSKGLGKACALLTDGRFSGGTSGLSIGHASPEAAEGGAIGLV 544
Query: 492 EDGDLIRIDVKAKRIDLLVDEEELKERKAK--------WKPKVKE--VKGYLKRYSSLVT 541
+GD + ID+ + I L++ +EEL R+A+ WKP+ ++ V L+ Y ++ T
Sbjct: 545 HEGDTVEIDIPNRSIRLVISDEELAARRAEMEARGSKAWKPENRDRYVSAALRAYGAMAT 604
Query: 542 SANTGAV 548
SA+ GAV
Sbjct: 605 SADKGAV 611
>pir||T36294 dihydroxy-acid dehydratase - Streptomyces coelicolor
>gi|4803691|emb|CAB42671.1| (AL049819) dihydroxy acid
dehydratase [Streptomyces coelicolor A3(2)]
Length = 617
Score = 461 bits (1174), Expect = e-129
Identities = 264/607 (43%), Positives = 368/607 (60%), Gaps = 59/607 (9%)
Query: 1 MRSDVIKKGIERAPHRALFKAMGLTDEELD-KPLIGIVNSFNELIPGHIHLRRIAEAVKT 59
+RS + G A RAL +A G+ ++ KP+I + NSF E +PGH HL + V
Sbjct: 4 LRSRTVTHGRNMAGARALMRASGVPGADIGRKPIIAVANSFTEFVPGHTHLAPVGRIVSE 63
Query: 60 GVRMSGGTPLEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASC 119
V +GG P EF+TI + DGIAMGHGGM YSLPSR+LIADS+E +V A+ D ++ I++C
Sbjct: 64 AVTAAGGIPREFNTIAVDDGIAMGHGGMLYSLPSRDLIADSVEYMVEAHCADALICISNC 123
Query: 120 DKIIPGMLMAMARLDIPAIFISGGPMLPGRFKGEYVDVKT--VFEAVGAVKAGKMSEKEL 177
DKI PGML A RL+IP +F+SGGPM GR V+T + +A+ K+S+ ++
Sbjct: 124 DKITPGMLNAALRLNIPTVFVSGGPMESGRATLVDGTVRTLDLVDAMSEAVNDKISDADI 183
Query: 178 KLLEDFACPGCGSCAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMK 237
+E+ ACP CGSC+GMFTAN+MN LTEA+G+SLP NG+ A + R + + ++
Sbjct: 184 LRIEENACPTCGSCSGMFTANSMNCLTEAIGLSLPGNGSVLATHTARKTLYENAARTVLD 243
Query: 238 LV-------EEDLKPSDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTF 290
L ++ + P +I TP AF +A+A+D+A+GGSTNT+LHL+A A+EA V L
Sbjct: 244 LTRRYYEQDDDSVLPRNIATPAAFGNAMALDIAMGGSTNTILHLLAAAQEAEVSYGLAEM 303
Query: 291 DEISEKTPTLVKISP----AGKHFVLDLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVG 346
D +S P L K++P +++ D++ AGG+ A++ L GL++ED +V ++
Sbjct: 304 DALSRSVPCLAKVAPNVAKDRTYYMEDVHRAGGIPALLGELHRGGLLNEDVHSVHSPSLA 363
Query: 347 ELLRDVSV----------------------------------LRDDV----IRPVTRPYL 368
+ L+ V L +D IR V Y
Sbjct: 364 DWLKTWDVRGGSPSKEAVELWHAAPGCVRSAEAFSQSERWDTLDEDAEGGCIRSVEHAYS 423
Query: 369 SRGGLMILYGSLAPKGAVLKVSAIPD-IETFEGEARVFDCEEDAVKAILSGDIEKGDVVV 427
GGL +L G+LA G V+K + + + I TFEG A V + +E+AV+ IL+ +++GDVVV
Sbjct: 424 KDGGLAVLRGNLAVDGCVVKTAGVDESIWTFEGPAVVCESQEEAVQKILTQQVKEGDVVV 483
Query: 428 IRYEGPKGGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIGHVSPEAAEGGP 487
IRYEGPKGGPGM+EML PTS + G GL + ALVTDGRFSG T GLSIGH SPEAA GG
Sbjct: 484 IRYEGPKGGPGMQEMLYPTSYLKGRGLGKACALVTDGRFSGGTSGLSIGHASPEAAAGGT 543
Query: 488 IALVEDGDLIRIDVKAKRIDLLVDEEELKERKAKW------KPKVKEVKGYLKRYSSLVT 541
IALVEDGD IRID+ + I+LLVD+ EL R+ K + ++V LK Y+++ T
Sbjct: 544 IALVEDGDRIRIDIPNRSIELLVDDAELTRREQALNGVYAPKNRDRKVSAALKAYAAMAT 603
Query: 542 SANTGAV 548
SA+ GAV
Sbjct: 604 SADKGAV 610
>sp|Q10318|ILV3_SCHPO PUTATIVE DIHYDROXY-ACID DEHYDRATASE, MITOCHONDRIAL PRECURSOR (DAD)
(2,3-DIHYDROXY ACID HYDROLYASE) >gi|7492518|pir||T37858
probable dihydroxy-acid dehydratase precursor - fission
yeast (Schizosaccharomyces pombe)
>gi|1213255|emb|CAA93689.1| (Z69795) putative
dihydroxy-acid dehydratase precursor
[Schizosaccharomyces pombe]
Length = 598
Score = 458 bits (1167), Expect = e-128
Identities = 245/554 (44%), Positives = 358/554 (64%), Gaps = 9/554 (1%)
Query: 3 SDVIKKGIERAPHRALFKAMGLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTGVR 62
S+ I + +A+ A GL +E++ KP +GI + + E P ++HL + VK GV+
Sbjct: 41 SETITGPKSQGASQAMLYATGLNEEDMKKPQVGIASCWYEGNPCNMHLLDLGRRVKEGVK 100
Query: 63 MSGGTPLEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCDKI 122
+G T +F+TIG+ DGI+MG GM+YSL SRE+IADSIE V++ +D V I CDK
Sbjct: 101 KAGLTGFQFNTIGVSDGISMGTTGMRYSLQSREIIADSIETVMQGQWYDANVSIPGCDKN 160
Query: 123 IPGMLMAMARLDIPAIFISGGPMLPGRFKGEY---VDVKTVFEAVGAVKAGKMSEKELKL 179
+PG L+AM R + P+I + GG + G + +D+ + F++ G GK+ E
Sbjct: 161 MPGCLIAMGRFNRPSIMVYGGSIRAGHSPCQNNAPIDIVSAFQSYGEFITGKIDEPTRHD 220
Query: 180 LEDFACPGCGSCAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKLV 239
+ ACPG G+C GM+TANTM + EA+G++LP + + A + + G I +L+
Sbjct: 221 IIRHACPGGGACGGMYTANTMASCAEAMGMTLPGSSSYLAGSPEKFAECEAAGSAIKRLL 280
Query: 240 EEDLKPSDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFDEISEKTPT 299
+D+KP DI+T AFE+A+ + M LGGSTN+VLHL+AIA+ G+ LTLD F +S +TP
Sbjct: 281 VDDIKPRDIMTRSAFENAMVLTMTLGGSTNSVLHLIAIAKSVGITLTLDDFQAVSNRTPF 340
Query: 300 LVKISPAGKHFVLDLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVGELLRDVSVLRD-- 357
+ + P+GK+ + DL+ GG+ +++K L GLI ITV+ KT+ E LR L +
Sbjct: 341 IADMKPSGKYVMEDLFAIGGIPSVLKYLHAEGLIDGSNITVTGKTLAENLRGFKDLAEGQ 400
Query: 358 DVIRPVTRPYLSRGGLMILYGSLAPKGAVLKVSAIPDIETFEGEARVFDCEEDAVKAILS 417
+IRP++ P + G L +L GSLAP+G+V K++ + F G+ARVFD E D + A+
Sbjct: 401 KIIRPLSNPIKTEGHLRVLRGSLAPEGSVAKITGKEGL-NFTGKARVFDAENDFIAALER 459
Query: 418 GDIEKGD--VVVIRYEGPKGGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSI 475
G+ +KG+ VV+IR+EGPKGGPGM EML P+SAI G GL +DVAL+TDGRFSG + G I
Sbjct: 460 GEFKKGEKTVVIIRFEGPKGGPGMPEMLKPSSAIMGAGLGKDVALLTDGRFSGGSHGFLI 519
Query: 476 GHVSPEAAEGGPIALVEDGDLIRIDVKAKRIDLLVDEEELKERKAKWK-PKVKEVKGYLK 534
GHV PEA GGPIALV+DGD+I I+ +DL+VDE+E+ R++ WK P +K +G L
Sbjct: 520 GHVDPEAQVGGPIALVQDGDVIEINAVKNTLDLMVDEKEMARRRSVWKAPPLKYQQGTLL 579
Query: 535 RYSSLVTSANTGAV 548
+Y+ V++A+ GAV
Sbjct: 580 KYARNVSTASKGAV 593
>dbj|BAB03011.1| (AP001297) dihydroxy-acid dehydratase [Arabidopsis thaliana]
Length = 608
Score = 458 bits (1165), Expect = e-128
Identities = 241/540 (44%), Positives = 356/540 (65%), Gaps = 5/540 (0%)
Query: 16 RALFKAMGLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTGVRMSGGTPLEFSTIG 75
+A+ +GL+D++L KP IGI + + E ++HL +++EAVK GV +G F+TIG
Sbjct: 70 QAILHGVGLSDDDLLKPQIGISSVWYEGNTCNMHLLKLSEAVKEGVENAGMVGFRFNTIG 129
Query: 76 ICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCDKIIPGMLMAMARLDI 135
+ D I+MG GM +SL SR+LIADSIE V+ A +DG + I CDK +PG +MAM RL+
Sbjct: 130 VSDAISMGTRGMCFSLQSRDLIADSIETVMSAQWYDGNISIPGCDKNMPGTIMAMGRLNR 189
Query: 136 PAIFISGGPMLPGRFKGEYVDVKTVFEAVGAVKAGKMSEKELKLLEDFACPGCGSCAGMF 195
P I + GG + PG F+ + D+ + F++ G +G +S+++ K + +CPG G+C GM+
Sbjct: 190 PGIMVYGGTIKPGHFQDKTYDIVSAFQSYGEFVSGSISDEQRKTVLHHSCPGAGACGGMY 249
Query: 196 TANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKLVEEDLKPSDILTPEAFE 255
TANTM + EA+G+SLP++ + PA ++ + G +++L++ DLKP DI+TP++
Sbjct: 250 TANTMASAIEAMGMSLPYSSSIPAEDPLKLDECRLAGKYLLELLKMDLKPRDIITPKSLR 309
Query: 256 DAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFDEISEKTPTLVKISPAGKHFVLDLY 315
+A+ MALGGSTN VLHL+AIAR G++LTLD F ++S+ P L + P+GK+ + D++
Sbjct: 310 NAMVSVMALGGSTNAVLHLIAIARSVGLELTLDDFQKVSDAVPFLADLKPSGKYVMEDIH 369
Query: 316 EAGGVLAIMKRLSELGLIHEDRITVSLKTVGELLRDVSVLRD--DVIRPVTRPYLSRGGL 373
+ GG A+++ L ELGL+ D +TV+ +T+ + L +V L + ++IRP++ P G +
Sbjct: 370 KIGGTPAVLRYLLELGLMDGDCMTVTGQTLAQNLENVPSLTEGQEIIRPLSNPIKETGHI 429
Query: 374 MILYGSLAPKGAVLKVSAIPDIETFEGEARVFDCEEDAVKAILSGDIE-KGDVVVIRYEG 432
IL G LAP G+V K++ + F G A VF+ EE + AI + + KG VVVIR EG
Sbjct: 430 QILRGDLAPDGSVAKITGKEGL-YFSGPALVFEGEESMLAAISADPMSFKGTVVVIRGEG 488
Query: 433 PKGGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIGHVSPEAAEGGPIALVE 492
PKGGPGM EML PTSAI G GL ++ AL+TDGRFSG + G +GH+ PEA EGGPI L++
Sbjct: 489 PKGGPGMPEMLTPTSAIMGAGLGKECALLTDGRFSGGSHGFVVGHICPEAQEGGPIGLIK 548
Query: 493 DGDLIRIDVKAKRIDLLVDEEELKERKAKW-KPKVKEVKGYLKRYSSLVTSANTGAVFRE 551
+GD+I ID+ KRID V EE+ +R+ KW P K +G L +Y V SA+ G V E
Sbjct: 549 NGDIITIDIGKKRIDTQVSPEEMNDRRKKWTAPAYKVNRGVLYKYIKNVQSASDGCVTDE 608
>gb|AAF13806.1|AF130814_2 (AF130814) dihydroxy acid dehydratase [Buchnera aphidicola]
Length = 613
Score = 456 bits (1161), Expect = e-127
Identities = 257/605 (42%), Positives = 370/605 (60%), Gaps = 59/605 (9%)
Query: 2 RSDVIKKGIERAPHRALFKAMGLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTGV 61
RS +G A R+L+KA G+TD + KP+I +VNSF E +PGHIHLR + + + + +
Sbjct: 5 RSSTTTQGRNMAGARSLWKATGMTDLDFKKPIIAVVNSFTEFVPGHIHLRNLGKLISSEI 64
Query: 62 RMSGGTPLEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCDK 121
+++GG EF+TI I DGIAMGH GM YSLPSRELIADSIE ++ A+ D ++ I++CDK
Sbjct: 65 KLTGGVAKEFNTIAIDDGIAMGHSGMLYSLPSRELIADSIEYMINAHCADAMICISNCDK 124
Query: 122 IIPGMLMAMARLDIPAIFISGGPMLPGRFKGEYVDVK-TVFEAVGAVKAGKMSEKELKLL 180
I PGMLMA RL+IP IFISGGPM G+ ++K + +A+ ++ + +
Sbjct: 125 ITPGMLMAALRLNIPCIFISGGPMESGKIFINEKEIKIDLIDAIKYSADPNSADDLVNQI 184
Query: 181 EDFACPGCGSCAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKLVE 240
ED +CP CGSC+G+FTAN+MN LTEALG+SLP NGT A + R ++ Q G I+K+ +
Sbjct: 185 EDSSCPTCGSCSGLFTANSMNCLTEALGLSLPGNGTLLATHVDRKKLFIQAGRLIVKITK 244
Query: 241 -------EDLKPSDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFDEI 293
E+L P +I + ++F +A+++D+A+GGSTNT+LHL+AIA+E + T+ D +
Sbjct: 245 DYYKNNNENLLPRNIASRQSFLNAMSLDIAMGGSTNTILHLLAIAKEGNIDFTMSDIDSL 304
Query: 294 SEKTPTLVKISP-AGKHFVLDLYEAGGVLAIMKRLSELGLIHE----------------- 335
S+K P L KISP + + + D + AGGV+ ++ L+ + L+++
Sbjct: 305 SKKVPHLCKISPNSTTYHMEDFHRAGGVMGLLAELNRINLLNKNINNVLGLNLETTLNIY 364
Query: 336 DRITVSLKTVGELLRDVSVLRDDVIRPVTRPY---------------------LSRGGLM 374
D +T K + + R + +I P T+ Y + GGL
Sbjct: 365 DILTTKDKNIINMFRAGPFGKKTII-PFTQSYRWPKLDKDRQKGCIRSYEFAFSNDGGLA 423
Query: 375 ILYGSLAPKGAVLKVSAI-PDIETFEGEARVFDCEEDAVKAILSGDIEKGDVVVIRYEGP 433
ILYG++A G V+K + + D F G A VF+ +EDAV+AIL G I+KG V+VIRYEGP
Sbjct: 424 ILYGNIAKNGCVVKTAGVKKDNLIFTGNAIVFESQEDAVRAILEGKIQKGHVIVIRYEGP 483
Query: 434 KGGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIGHVSPEAAEGGPIALVED 493
KGGPGM+EML PT+ + MGLD+ AL+TDGRFSG T GLSIGH+SPEAA G IAL+++
Sbjct: 484 KGGPGMQEMLYPTTYLKSMGLDQHCALITDGRFSGGTSGLSIGHISPEAASKGNIALIKN 543
Query: 494 GDLIRIDVKAKRIDLLVDEEEL--------KERKAKWKPKVKE--VKGYLKRYSSLVTSA 543
D I I++ + I L + +EL K+ + P ++ V LK Y+ SA
Sbjct: 544 SDCININIPDRIIHLDITNDELLLRIENENKKGSLSYTPLYRQRYVSPALKMYAFFAMSA 603
Query: 544 NTGAV 548
+ GAV
Sbjct: 604 DKGAV 608
>emb|CAB57218.1| (AJ012293) dihydroxy-acid dehydratase [Corynebacterium glutamicum]
Length = 612
Score = 455 bits (1159), Expect = e-127
Identities = 255/608 (41%), Positives = 371/608 (60%), Gaps = 63/608 (10%)
Query: 1 MRSDVIKKGIERAPHRALFKAMGLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTG 60
+RS V G A RAL++A G + E KP++ IVNS+ + +PGH+HL+ + + V
Sbjct: 4 LRSKVTTVGRNAAGARALWRATGTKENEFGKPIVAIVNSYTQFVPGHVHLKNVGDIVADA 63
Query: 61 VRMSGGTPLEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCD 120
VR +GG P EF+TI + DGIAMGHGGM YSLPSRE+IADS+E +V A+ D +V I++CD
Sbjct: 64 VRKAGGVPKEFNTI-VDDGIAMGHGGMLYSLPSREIIADSVEYMVNAHTADAMVCISNCD 122
Query: 121 KIIPGMLMAMARLDIPAIFISGGPMLPGRFKGEYVD-----VKTVFEAVGAVKAGKMSEK 175
KI PGML A RL+IP +F+SGGPM G K V+ + A+ A + + +
Sbjct: 123 KITPGMLNAAMRLNIPVVFVSGGPMEAG--KAVVVERVAHAPTDLITAISASASDAVDDA 180
Query: 176 ELKLLEDFACPGCGSCAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQI 235
L +E ACP CGSC+GMFTAN+MN LTEALG+SLP NG+ A +A R + ++ G +
Sbjct: 181 GLAAVERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSTLATHAARRALFEKAGETV 240
Query: 236 MKLV-------EEDLKPSDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLD 288
++L +E + P I T +AFE+A+A+DMA+GGSTNT+LH++A A+E V L
Sbjct: 241 VELCRRYYGEEDESVLPRGIATKKAFENAMALDMAMGGSTNTILHILAAAQEGEVDFDLA 300
Query: 289 TFDEISEKTPTLVKISPAGKHFVLDLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVGEL 348
DE+S+ P L K++P + + D++ AG + A++ L+ GL+++D +V +
Sbjct: 301 DIDELSKNVPCLSKVAPNSDYHMEDVHRAGRIPALLGELNRGGLLNKDVHSVHSNDLEGW 360
Query: 349 LRDVSV----------------------------------LRDDV----IRPVTRPYLSR 370
L D + L D IR V Y +
Sbjct: 361 LDDWDIRSGKTTEVATELFHAAPGGIRTTEAFSTENRWDELDTDAAKGCIRDVEHAYTAD 420
Query: 371 GGLMILYGSLAPKGAVLKVSAI-PDIETFEGEARVFDCEEDAVKAILSGDIEKGDVVVIR 429
GGL++L G+++P GAV+K + I ++ F G ARV + +E+AV IL+ I+ G+V+V+R
Sbjct: 421 GGLVVLRGNISPDGAVIKSAGIEEELWNFTGPARVVESQEEAVSVILTKTIQAGEVLVVR 480
Query: 430 YEGPKGGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIGHVSPEAAEGGPIA 489
YEGP GGPGM+EML PT+ + G GL + AL+TDGRFSG + GLSIGHVSPEAA GG I
Sbjct: 481 YEGPSGGPGMQEMLHPTAFLKGSGLGKKCALITDGRFSGGSSGLSIGHVSPEAAHGGVIG 540
Query: 490 LVEDGDLIRIDVKAKRIDLLVDEEELKERK-------AKWKP--KVKEVKGYLKRYSSLV 540
L+E+GD++ IDV +++++ V +EEL+ R+ W+P + + V L+ Y+ +
Sbjct: 541 LIENGDIVSIDVHNRKLEVQVSDEELQRRRDAMNASEKPWQPVNRNRVVTKALRAYAKMA 600
Query: 541 TSANTGAV 548
TSA+ GAV
Sbjct: 601 TSADKGAV 608
>sp|P57656|ILVD_BUCAI DIHYDROXY-ACID DEHYDRATASE (DAD) >gi|10039251|dbj|BAB13285.1|
(AP001119) dihydroxy-acid dehydratase [Buchnera sp. APS]
Length = 617
Score = 451 bits (1149), Expect = e-126
Identities = 250/606 (41%), Positives = 369/606 (60%), Gaps = 61/606 (10%)
Query: 2 RSDVIKKGIERAPHRALFKAMGLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTGV 61
RS +G + R+L++A G+T+++ KP+I +VNSF++ +PGHIHL+ + + + +
Sbjct: 5 RSFTTTQGRNMSGARSLWRATGMTEKDFTKPIIAVVNSFSQFVPGHIHLQEVGKLICGEI 64
Query: 62 RMSGGTPLEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCDK 121
+ SGG EF+TI I DGIAMGH GM YSLPSRELIADSIE VV A+ D ++ I++CDK
Sbjct: 65 QKSGGVAKEFNTIAIDDGIAMGHSGMLYSLPSRELIADSIEYVVNAHCADAMICISNCDK 124
Query: 122 IIPGMLMAMARLDIPAIFISGGPMLPGRFKGEYVDVKTVFEAVGAVKAG---KMSEKELK 178
I PGMLMA RL+IP++FISGGPM G+ + +K + V A+ G +S+ +K
Sbjct: 125 ITPGMLMASLRLNIPSVFISGGPMEAGKIQKNNKTIK--IDLVDAIINGGKSHISDDFIK 182
Query: 179 LLEDFACPGCGSCAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKL 238
+E ACP CGSC+GMFTAN+MN LTEA+G++LP NGT A + R + ++ I+K+
Sbjct: 183 DIEASACPTCGSCSGMFTANSMNCLTEAIGLALPGNGTLLATHIDRKNLFIKSAQIIVKI 242
Query: 239 VEEDLK-------PSDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFD 291
E+ K P +I E+FE+A+ +D+A+GGSTNT+LHL+A A+EA V + +
Sbjct: 243 TEDYYKKNNTNVLPRNIANKESFENAMMLDIAMGGSTNTILHLLAAAQEAKVDFKMSNIN 302
Query: 292 EISEKTPTLVKISPA-GKHFVLDLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVGELLR 350
++S+K P + K++P+ + V D++ AGGV+ I+ L+ L+H++ + + E L
Sbjct: 303 KLSKKIPHICKVAPSTSLYHVEDVHRAGGVMGILGELNRFNLLHKNTRNILQLNLEETLD 362
Query: 351 DVSVL-------------------------------------RDDVIRPVTRPYLSRGGL 373
+ + ++ IR Y GGL
Sbjct: 363 EYDIFSTNNPDVINMFQAGPGGIRTTKAYSQNFRWTRLDYDRKNGCIRSCKHAYSQDGGL 422
Query: 374 MILYGSLAPKGAVLKVSAIPDIE-TFEGEARVFDCEEDAVKAILSGDIEKGDVVVIRYEG 432
ILYG+LA G ++K + I F G A+V++ +E+A +IL+G+I GD++VIRYEG
Sbjct: 423 AILYGNLAKNGCIIKTAGIDAKNYIFSGVAKVYESQEEAASSILNGEIISGDIIVIRYEG 482
Query: 433 PKGGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIGHVSPEAAEGGPIALVE 492
PKGGPGM+EML PT+ + M LD+ AL+TDGRFSG T G+SIGH+SPEAA G IALV+
Sbjct: 483 PKGGPGMQEMLYPTTYLKSMNLDKTCALITDGRFSGGTSGISIGHISPEAANKGIIALVK 542
Query: 493 DGDLIRIDVKAKRIDLLVDEEELKER--------KAKWKP--KVKEVKGYLKRYSSLVTS 542
+GD+I I++ + I L + E+EL R +KP + + + LK Y+ TS
Sbjct: 543 NGDIININIPERTIHLNITEKELSHRILQEESKGPLSYKPHSRKRYISSALKAYAFFSTS 602
Query: 543 ANTGAV 548
A+ GAV
Sbjct: 603 ADQGAV 608
>sp|O51887|ILVD_BUCAP DIHYDROXY-ACID DEHYDRATASE (DAD) >gi|2827033|gb|AAC38125.1|
(AF008210) dihydroxy acid dehydratase [Buchnera
aphidicola]
Length = 617
Score = 446 bits (1136), Expect = e-124
Identities = 252/606 (41%), Positives = 367/606 (59%), Gaps = 61/606 (10%)
Query: 2 RSDVIKKGIERAPHRALFKAMGLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTGV 61
RS G + R+L++A G+TDE+ KP+I IVNSF++ +PGHIHL+ + + + +
Sbjct: 5 RSFTTTHGRNMSGARSLWRATGMTDEDFKKPIIAIVNSFSQFVPGHIHLQEVGKIISKEI 64
Query: 62 RMSGGTPLEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCDK 121
+ GG P EF+TI I DGIAMGH GM YSLPSRELIADSIE V+ A+ D ++ +++CDK
Sbjct: 65 KKYGGVPKEFNTIAIDDGIAMGHSGMLYSLPSRELIADSIEYVINAHCVDSMICVSNCDK 124
Query: 122 IIPGMLMAMARLDIPAIFISGGPMLPGRFKGEYVDVKTVFEAVGAVKAGKMSEKE---LK 178
I P M MA RL+IP++F+SGGPM G+ K + D + V A+ G S K ++
Sbjct: 125 ITPAMFMASLRLNIPSVFVSGGPMEAGKIKTK--DKTKKIDLVDAIIHGGDSNKSDDFIR 182
Query: 179 LLEDFACPGCGSCAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKL 238
+E ACP CGSC+GMFTAN+MN L EA+G+SLP NGT A + R ++ K++ I+K+
Sbjct: 183 EIELSACPTCGSCSGMFTANSMNCLIEAIGLSLPGNGTLLATHIDRKKLFKKSARNIVKI 242
Query: 239 VEE-------DLKPSDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFD 291
++ ++ P +I E+FE+A+A+D+A+GGSTNT+LHL+A A E V + +
Sbjct: 243 TKDYYLNNNKNVLPRNIANKESFENAMALDIAMGGSTNTILHLLAAAYEGKVDFKMSDIN 302
Query: 292 EISEKTPTLVKISPA-GKHFVLDLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVGELLR 350
+S+K P + K++P+ + V D++ AGGV+ I+ L+ L+++ + + + L+
Sbjct: 303 NLSKKIPHICKVAPSTNLYHVEDVHRAGGVMRILGELNRSNLLNKKTENILGLNLEKTLK 362
Query: 351 DVSVL----------------------------------RDDV---IRPVTRPYLSRGGL 373
+L +D V IR Y GGL
Sbjct: 363 KYDILSTKNKNVIKMFHAGPGGNRTIKPFSQNYRWNKLDKDRVNGCIRSHENAYSKNGGL 422
Query: 374 MILYGSLAPKGAVLKVSAIPDIE-TFEGEARVFDCEEDAVKAILSGDIEKGDVVVIRYEG 432
+LYG+LA G ++K ++I F G A+V++ +E+AV AILSG I GDV+VIRYEG
Sbjct: 423 SVLYGNLAKNGCIIKTASIDKKHYIFSGPAKVYESQEEAVSAILSGKIIAGDVIVIRYEG 482
Query: 433 PKGGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIGHVSPEAAEGGPIALVE 492
PKGGPGM+EML PT+ + + LD+ AL+TDGRFSG T GLSIGH+SPEAA G IALVE
Sbjct: 483 PKGGPGMQEMLYPTTYLKSINLDKQCALITDGRFSGGTSGLSIGHISPEAANKGIIALVE 542
Query: 493 DGDLIRIDVKAKRIDLLVDEEELKERKAK--------WKP--KVKEVKGYLKRYSSLVTS 542
+GD I+I++ K I L + E+EL R K +KP + + + L+ Y+ S
Sbjct: 543 NGDDIQINIVNKTIHLNITEKELNLRIIKENAKGLKAYKPLNRKRNISFALRAYAHFALS 602
Query: 543 ANTGAV 548
A+ GA+
Sbjct: 603 ADKGAI 608
>gb|AAF13802.1|AF130813_2 (AF130813) dihydroxy acid dehydratase [Buchnera aphidicola]
Length = 613
Score = 444 bits (1131), Expect = e-124
Identities = 252/604 (41%), Positives = 364/604 (59%), Gaps = 57/604 (9%)
Query: 2 RSDVIKKGIERAPHRALFKAMGLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTGV 61
RS +G A RAL+KA G+TD + +KP+I +VNSF E +PGHIHL+ + V + +
Sbjct: 5 RSSTTTQGRNMAGARALWKATGMTDSDFNKPIIAVVNSFTEFVPGHIHLKELGTLVSSII 64
Query: 62 RMSGGTPLEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCDK 121
++ GG EF+TI I DGIAMGH GM YSLPSRELIADSIE ++ A+ D ++ I++CDK
Sbjct: 65 KLEGGVAKEFNTIAIDDGIAMGHSGMLYSLPSRELIADSIEYMINAHCADAMICISNCDK 124
Query: 122 IIPGMLMAMARLDIPAIFISGGPMLPGRFKGEYVDVK-TVFEAVGAVKAGKMSEKELKLL 180
I PGMLMA RL+IP +F+SGGPM GR + ++K + +A+ S+ +
Sbjct: 125 ITPGMLMAALRLNIPCVFVSGGPMESGRIVVDGKEIKINLVDAIVYGANPNYSDALASRI 184
Query: 181 EDFACPGCGSCAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKLVE 240
E+ ACP CGSC+G+FTAN+MN LTEALG+SLP NGT A + R ++ +G I+K+ +
Sbjct: 185 ENCACPTCGSCSGLFTANSMNCLTEALGLSLPGNGTLLATHIDRKKLFIDSGKLIVKITK 244
Query: 241 E-------DLKPSDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFDEI 293
E P I + E+F +A+++D++ GGSTNT+LHL+A+A+E V + D +
Sbjct: 245 EYYEDNNTSFLPRSIASRESFLNAMSLDISTGGSTNTILHLLAMAQEGQVDFKMSDIDLL 304
Query: 294 SEKTPTLVKISP-AGKHFVLDLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVGELLRDV 352
S K P L KI+P + + + D + AGGV+ ++ L+ + L++ + + ++ +L
Sbjct: 305 SRKIPNLCKIAPNSDVYHMEDFHRAGGVIGLLAELNRVSLLNNNVKNILGLSLDVVLNKY 364
Query: 353 SVLR---DDVIR-------------PVTRPYLSR---------------------GGLMI 375
+L+ DVI P T+ Y + GGL I
Sbjct: 365 DILKTKNQDVIEMFHAGPLGNKTSIPFTQSYRWKSLDKDRKKGCIRSYENAFSYDGGLAI 424
Query: 376 LYGSLAPKGAVLKVSAIPDIE-TFEGEARVFDCEEDAVKAILSGDIEKGDVVVIRYEGPK 434
LYG++A G V+K + + FEG A VF+ +E+A+KAIL ++KG VVVIRYEGPK
Sbjct: 425 LYGNIAKNGCVVKTAGVKKGNLIFEGFAIVFESQEEALKAILENKVKKGHVVVIRYEGPK 484
Query: 435 GGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIGHVSPEAAEGGPIALVEDG 494
GGPGM+EML PT+ + M LD AL+TDGRFSG T GLSIGH+SPEAA G IAL+ +
Sbjct: 485 GGPGMQEMLYPTTYLKSMNLDEHCALITDGRFSGGTSGLSIGHISPEAANKGNIALIRNN 544
Query: 495 DLIRIDVKAKRIDLLVDEEELKER--------KAKWKPKVKE--VKGYLKRYSSLVTSAN 544
D+I I++ + I+L + +E R K+ + P+ ++ V LK Y+ TSA+
Sbjct: 545 DVININIPNRTINLDITNDEFLNRMHNEIQRGKSSYTPQFRKRFVSSALKMYALFATSAD 604
Query: 545 TGAV 548
GAV
Sbjct: 605 KGAV 608
>sp|Q02139|ILVD_LACLA DIHYDROXY-ACID DEHYDRATASE (DAD) >gi|486729|pir||S35137 probable
phosphogluconate dehydratase (EC 4.2.1.12) - Lactococcus
lactis subsp. lactis >gi|2565156|gb|AAB81918.1| (U92974)
IlvD [Lactococcus lactis]
Length = 570
Score = 438 bits (1115), Expect = e-122
Identities = 239/538 (44%), Positives = 339/538 (62%), Gaps = 6/538 (1%)
Query: 16 RALFKAMGLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTGVRMSGGT-PLEFSTI 74
+A++ +G DE+ K +GIV+ + P ++HL + +K+ V + G L+F TI
Sbjct: 31 QAMYYGIGFKDEDFKKAQVGIVSMDWDGNPCNMHLGTLGSKIKSSVNQTDGLIGLQFHTI 90
Query: 75 GICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCDKIIPGMLMAMARLD 134
G+ DGIA G GM+YSL SRE+IADSIE A +D IV I CDK +PG ++ MARL+
Sbjct: 91 GVSDGIANGKLGMRYSLVSREVIADSIETNAGAEYYDAIVAIPGCDKNMPGSIIGMARLN 150
Query: 135 IPAIFISGGPMLPGRFKGEYVDVKTVFEAVGAVKAGKMSEKELKLLEDFACPGCGSCAGM 194
P+I + GG + G +KGE +++ + FEA+G G +S+++ + A PG G+C GM
Sbjct: 151 RPSIMVYGGTIEHGEYKGEKLNIVSAFEALGQKITGNISDEDYHGVICNAIPGQGACGGM 210
Query: 195 FTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKLVEEDLKPSDILTPEAF 254
+TANT+ A E LG+SLP++ + PAV + G+ I L+E+D+KPSDI+T EAF
Sbjct: 211 YTANTLAAAIETLGMSLPYSSSNPAVSQEKQEECDDIGLAIKNLLEKDIKPSDIMTKEAF 270
Query: 255 EDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFDEISEKTPTLVKISPAGKHFVLDL 314
E+AI + M LGGSTN VLH++A+A GV++T D F IS+ P L P+GK+ + DL
Sbjct: 271 ENAITIVMVLGGSTNAVLHIIAMANAIGVEITQDDFQRISDIIPVLGDFKPSGKYMMEDL 330
Query: 315 YEAGGVLAIMKRLSELGLIHEDRITVSLKTVGELLR---DVSVLRDDVIRPVTRPYLSRG 371
++ GG+ A++K L + G +H D +TV+ KT+ E + D+ D++RP+ P + G
Sbjct: 331 HKIGGLPAVLKYLLKEGKLHGDCLTVTGKTLAENVETALDLDFDSQDIMRPLKNPIKATG 390
Query: 372 GLMILYGSLAPKGAVLKVSAIPDIETFEGEARVFDCEEDAVKAILSGDIEKGDVVVIRYE 431
L ILYG+LA G+V K+S + E F+G ARVFD E+ + I SG + GDV VIR
Sbjct: 391 HLQILYGNLAQGGSVAKISG-KEGEFFKGTARVFDGEQHFIDGIESGRLHAGDVAVIRNI 449
Query: 432 GPKGGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIGHVSPEAAEGGPIALV 491
GP GGPGM EML PTSA+ G GL + AL+TDGRFSG T G +GH+ PEA EGG I LV
Sbjct: 450 GPVGGPGMPEMLKPTSALIGAGLGKSCALITDGRFSGGTHGFVVGHIVPEAVEGGLIGLV 509
Query: 492 EDGDLIRIDVKAKRIDLLVDEEELKERKAKW-KPKVKEVKGYLKRYSSLVTSANTGAV 548
ED D+I ID I L V EE+ +R+A + KP K +G L +++ L A+ G V
Sbjct: 510 EDDDIIEIDAVNNSISLKVSNEEIAKRRANYQKPTPKATRGVLAKFAKLTRPASEGCV 567
>gi|6322476 dihydroxyacid dehydratase; Ilv3p [Saccharomyces cerevisiae]
>gi|1170543|sp|P39522|ILV3_YEAST DIHYDROXY-ACID
DEHYDRATASE, MITOCHONDRIAL PRECURSOR (DAD)
(2,3-DIHYDROXY ACID HYDROLYASE) >gi|1077091|pir||S55205
dihydroxy-acid dehydratase (EC 4.2.1.9) - yeast
(Saccharomyces cerevisiae) >gi|854590|emb|CAA60939.1|
(X87611) dihydroxyacid dehydratase [Saccharomyces
cerevisiae] >gi|1015650|emb|CAA89540.1| (Z49516) ORF
YJR016c [Saccharomyces cerevisiae]
Length = 585
Score = 437 bits (1112), Expect = e-121
Identities = 234/544 (43%), Positives = 346/544 (63%), Gaps = 12/544 (2%)
Query: 16 RALFKAMGLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTGVRMSGGTPLEFSTIG 75
+A+ A G E+ KP +G+ + + P ++HL + + +G ++F+TIG
Sbjct: 40 QAMLYATGFKKEDFKKPQVGVGSCWWSGNPCNMHLLDLNNRCSQSIEKAGLKAMQFNTIG 99
Query: 76 ICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCDKIIPGMLMAMARLDI 135
+ DGI+MG GM+YSL SRE+IADS E ++ A ++D + I SCDK +PG++MAM R +
Sbjct: 100 VSDGISMGTKGMRYSLQSREIIADSFETIMMAQHYDANIAIPSCDKNMPGVMMAMGRHNR 159
Query: 136 PAIFISGGPMLPGRFK------GEYVDVKTVFEAVGAVKAGKMSEKELKLLEDFACPGCG 189
P+I + GG +LPG + +D+ + F++ G + + +E+E + + + ACPG G
Sbjct: 160 PSIMVYGGTILPGHPTCGSSKISKNIDIVSAFQSYGEYISKQFTEEEREDVVEHACPGPG 219
Query: 190 SCAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKLVEEDLKPSDIL 249
SC GM+TANTM + E LG+++P + + PAV ++ G I K +E + P DIL
Sbjct: 220 SCGGMYTANTMASAAEVLGLTIPNSSSFPAVSKEKLAECDNIGEYIKKTMELGILPRDIL 279
Query: 250 TPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFDEISEKTPTLVKISPAGKH 309
T EAFE+AI +A GGSTN VLHL+A+A AGVKL+ D F IS+ TP + P+GK+
Sbjct: 280 TKEAFENAITYVVATGGSTNAVLHLVAVAHSAGVKLSPDDFQRISDTTPLIGDFKPSGKY 339
Query: 310 FVLDLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVGELLRDVSVLRD--DVIRPVTRPY 367
+ DL GG +++K L E ++H + +TV+ T+ E + L + ++I+P++ P
Sbjct: 340 VMADLINVGGTQSVIKYLYENNMLHGNTMTVTGDTLAERAKKAPSLPEGQEIIKPLSHPI 399
Query: 368 LSRGGLMILYGSLAPKGAVLKVSAIPDIETFEGEARVFDCEEDAVKAILSGDIEKGD--V 425
+ G L ILYGSLAP GAV K++ + F+G ARVF+ E ++A+ G+I+KG+ V
Sbjct: 400 KANGHLQILYGSLAPGGAVGKITG-KEGTYFKGRARVFEEEGAFIEALERGEIKKGEKTV 458
Query: 426 VVIRYEGPKGGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIGHVSPEAAEG 485
VVIRYEGP+G PGM EML P+SA+ G GL +DVAL+TDGRFSG + G IGH+ PEAAEG
Sbjct: 459 VVIRYEGPRGAPGMPEMLKPSSALMGYGLGKDVALLTDGRFSGGSHGFLIGHIVPEAAEG 518
Query: 486 GPIALVEDGDLIRIDVKAKRIDLLVDEEELKERKAKW-KPKVKEVKGYLKRYSSLVTSAN 544
GPI LV DGD I ID +IDLLV ++E+ +RK W P + +G L +Y+ LV++A+
Sbjct: 519 GPIGLVRDGDEIIIDADNNKIDLLVSDKEMAQRKQSWVAPPPRYTRGTLSKYAKLVSNAS 578
Query: 545 TGAV 548
G V
Sbjct: 579 NGCV 582
>pir||T43179 probable dehydratase (EC 4.2.1.-) - fission yeast
(Schizosaccharomyces pombe) (fragment)
>gi|1749716|dbj|BAA13915.1| (D89254) similar to
Saccharomyces cerevisiae dihydroxy-acid dehydratase
precursor, SWISS-PROT Accession Number P39522
[Schizosaccharomyces pombe]
Length = 513
Score = 435 bits (1106), Expect = e-121
Identities = 232/509 (45%), Positives = 333/509 (64%), Gaps = 9/509 (1%)
Query: 48 IHLRRIAEAVKTGVRMSGGTPLEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRA 107
+HL + VK GV+ +G T +F+TIG+ DGI+MG GM+YSL SRE+IADSIE V++
Sbjct: 1 MHLLDLGRRVKEGVKKAGLTGFQFNTIGVSDGISMGTTGMRYSLQSREIIADSIETVMQG 60
Query: 108 YNFDGIVMIASCDKIIPGMLMAMARLDIPAIFISGGPMLPGRFKGEY---VDVKTVFEAV 164
+D V I CDK +PG L+AM R + P+I + GG + G + VD+ + F++
Sbjct: 61 QWYDANVSIPGCDKNMPGCLIAMGRFNRPSIMVYGGSIRAGHSPCQNNAPVDIVSAFQSF 120
Query: 165 GAVKAGKMSEKELKLLEDFACPGCGSCAGMFTANTMNALTEALGISLPWNGTAPAVYAHR 224
G GK+ E + ACPG G+C GM+TANTM + EA+G++LP + + A +
Sbjct: 121 GEFITGKIDEPTRHDIIRHACPGGGACGGMYTANTMASCAEAMGMTLPGSSSYLAGSPEK 180
Query: 225 IRIAKQTGMQIMKLVEEDLKPSDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVK 284
G I +L+ +D++P DILT AFE+A+ + M LGGSTN+VLHL+A A+ G+
Sbjct: 181 FAECAAAGSAIKRLLVDDIEPRDILTRFAFENAMVLTMTLGGSTNSVLHLIATAKSVGIT 240
Query: 285 LTLDTFDEISEKTPTLVKISPAGKHFVLDLYEAGGVLAIMKRLSELGLIHEDRITVSLKT 344
LTLD F +S +TP + + P+GK+ + DL+ GG+ +++K L GLI ITV+ KT
Sbjct: 241 LTLDDFQAVSNRTPFIADMKPSGKYVMEDLFAIGGIPSVLKYLHAEGLIDGSNITVTGKT 300
Query: 345 VGELLRDVSVLRDD--VIRPVTRPYLSRGGLMILYGSLAPKGAVLKVSAIPDIETFEGEA 402
+ E LR L +D +IRP++ P + G L +L GSLAP+G+V K++ + F G+A
Sbjct: 301 LAENLRGFKDLAEDQKIIRPLSNPIKTEGHLRVLRGSLAPEGSVAKITGKEGL-NFTGKA 359
Query: 403 RVFDCEEDAVKAILSGDIEKGD--VVVIRYEGPKGGPGMREMLAPTSAIAGMGLDRDVAL 460
RVFD E D + A+ G+ +KG+ VV+IR+EGPKGGPGM EML P+SAI G GL +DVAL
Sbjct: 360 RVFDAENDFIAALERGEFKKGEKTVVIIRFEGPKGGPGMPEMLKPSSAIMGAGLGKDVAL 419
Query: 461 VTDGRFSGATRGLSIGHVSPEAAEGGPIALVEDGDLIRIDVKAKRIDLLVDEEELKERKA 520
+TDGRFSG + G IGHV PEA GGPIALV+DGD+I I+ +D++VDE+E+ R++
Sbjct: 420 LTDGRFSGGSHGFLIGHVDPEAQVGGPIALVQDGDVIEINAVKNTLDVMVDEKEMARRRS 479
Query: 521 KWK-PKVKEVKGYLKRYSSLVTSANTGAV 548
WK P +K +G L +Y+ V++A+ GAV
Sbjct: 480 VWKAPPLKYQQGTLLKYARNVSTASKGAV 508
>sp|P31959|ILVD_CLOPA DIHYDROXY-ACID DEHYDRATASE (DAD) >gi|144843|gb|AAC41395.1| (L06666)
dihydroxyacid dehydrase [Clostridium pasteurianum]
Length = 286
Score = 380 bits (966), Expect = e-104
Identities = 178/285 (62%), Positives = 233/285 (81%)
Query: 1 MRSDVIKKGIERAPHRALFKAMGLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTG 60
MRSD +KG+E+APHR+LFKA+G DEE+++PLIGI +S++E+IPGH++L ++ +AVK G
Sbjct: 1 MRSDSARKGLEKAPHRSLFKALGFIDEEMERPLIGIASSYSEIIPGHMNLDKVVQAVKDG 60
Query: 61 VRMSGGTPLEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCD 120
VRM+GG P+ F TIG+CDGI+M H GM YSLPSR+LIADS+E V A+ FDGIV++ +CD
Sbjct: 61 VRMAGGVPVTFGTIGVCDGISMNHKGMSYSLPSRQLIADSVEIVASAHAFDGIVLVPNCD 120
Query: 121 KIIPGMLMAMARLDIPAIFISGGPMLPGRFKGEYVDVKTVFEAVGAVKAGKMSEKELKLL 180
K++PGM+MA ARLDIPAI ISGGPML G G+ D+ VFEAVGAVKAG M+E+EL L
Sbjct: 121 KVVPGMMMAAARLDIPAIVISGGPMLAGNTCGKATDLSGVFEAVGAVKAGNMTEEELSEL 180
Query: 181 EDFACPGCGSCAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKLVE 240
E+ ACP CGSC+GM+TAN+MN L+E LG++LP+NGT PAVY+ R+R+AK +GM+I+ LV+
Sbjct: 181 ENTACPTCGSCSGMYTANSMNCLSEVLGLALPYNGTIPAVYSERLRLAKTSGMKIVDLVK 240
Query: 241 EDLKPSDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVKL 285
+ L PS ILT EAF +AI DMALG STN++LHL AIA E G+ +
Sbjct: 241 KGLTPSKILTEEAFMNAITADMALGCSTNSLLHLPAIANEVGITI 285
>pir||T36902 probable dihydroxy-acid dehydratase - Streptomyces coelicolor
>gi|5419997|emb|CAB46389.1| (AL096743) putative
dihydroxy-acid dehydratase [Streptomyces coelicolor
A3(2)]
Length = 576
Score = 368 bits (935), Expect = e-101
Identities = 220/550 (40%), Positives = 325/550 (59%), Gaps = 17/550 (3%)
Query: 9 GIERAPHRALFKAMG-LTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTGVRMSGGT 67
G+ HRA + +G L +E L KP+I I+N+++++ P H+HLR A+AVK GV +GG
Sbjct: 20 GLRSFSHRARTRQLGYLPEEHLGKPVIAILNTWSDINPCHVHLRDRAQAVKRGVWQAGGF 79
Query: 68 PLEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCDKIIPGML 127
PLEF + + M Y R L+A E ++R+Y DG V++ CDK P +L
Sbjct: 80 PLEFPVSTLSETFQKPTP-MLY----RNLLAMETEELLRSYPVDGAVLMGGCDKSTPALL 134
Query: 128 MAMARLDIPAIFISGGPMLPGRFKGEYVDVKT-VFEAVGAVKAGKMSEKELKLLEDFACP 186
M A +D+PA+F+ GPMLPG ++GE + T +++ +AG + + E++ LE
Sbjct: 135 MGAATVDLPAVFVPAGPMLPGHWRGETLGSGTDMWKYWDDKRAGLIGDCEMQELESGLAR 194
Query: 187 GCGSCAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKLVEEDLKPS 246
G C M TA+T+ A EALG+++P + PAV + R+A G+++++LV D + S
Sbjct: 195 SPGHCMTMGTASTLTAAAEALGVTVPGASSIPAVDSGHDRMAAAAGLRVVELVHRDRRLS 254
Query: 247 DILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFDEISEKTPTLVKISPA 306
DILT +AFEDA+ + LGGSTN V+HL+A+A AGV LTLD FD I+ P L + P
Sbjct: 255 DILTADAFEDAVTTVLGLGGSTNAVIHLIAMAGRAGVTLTLDDFDRIARTVPVLANVRPG 314
Query: 307 GK-HFVLDLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVGELLRDVSVLRDDVIRPVTR 365
G+ H + D + AGG+ + R+++ L+H DR TV+ T+ E L V DDVIRP
Sbjct: 315 GQTHLMEDFHFAGGLPGFLSRITD--LLHLDRPTVAHDTLREQLDGALVHHDDVIRPRDN 372
Query: 366 PYLSRGGLMILYGSLAPKGAVLK-VSAIPDIETFEGEARVFDCEEDAVKAILSGD--IEK 422
P + GG+ +L G+L P GAV+K ++A P + G A VFD + + I + I
Sbjct: 373 PVANEGGVAVLRGNLCPDGAVIKHIAAEPHLLKHTGPAVVFDDYKTMQRTINDPELGITA 432
Query: 423 GDVVVIRYEGPKGGPGMRE--MLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIGHVSP 480
V+V+R GPKGGPGM E ML + G+ RD+ ++D R SG + G + HV+P
Sbjct: 433 DSVLVLRNAGPKGGPGMPEYGMLPIPDHLLKQGV-RDMVRISDARMSGTSYGACVLHVAP 491
Query: 481 EAAEGGPIALVEDGDLIRIDVKAKRIDLLVDEEELKERKAKW-KPKVKEVKGYLKRYSSL 539
E+ GGP+ALV GD I +DV A+ + L VD+EEL+ R+A W P + +GY Y+
Sbjct: 492 ESYVGGPLALVRTGDSITLDVGARTLHLGVDDEELERRRAAWTPPPARYERGYGALYNEQ 551
Query: 540 VTSANTGAVF 549
+T A+TG F
Sbjct: 552 ITQADTGCDF 561
>emb|CAB61588.1| (AL133210) putative dihydroxy-acid dehydratase [Streptomyces
coelicolor A3(2)]
Length = 596
Score = 363 bits (921), Expect = 4e-99
Identities = 228/562 (40%), Positives = 325/562 (57%), Gaps = 33/562 (5%)
Query: 15 HRALFKAMGLTDEELD-KPLIGIVNSFNELIPGHIHLRRIAEAVKTGVRMSGGTPLEFST 73
+R+ ++ G E D +P+IGI S +EL P + HL R+AEAVK GV +GG PL+F T
Sbjct: 25 YRSWMRSQGFGHEVFDGRPVIGIATSASELAPCNAHLTRVAEAVKRGVWQAGGFPLQFPT 84
Query: 74 IGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCDKIIPGMLMAMARL 133
+ + + M M Y R L+A +E ++RA DG+V+++ CDK P MLM A +
Sbjct: 85 MATGETL-MRPTAMLY----RNLMAMEVEELIRANPLDGVVLLSGCDKTTPAMLMGAASV 139
Query: 134 DIPAIFISGGPMLPGRFKGEYVDVKT-VFEAVGAVKAGKMSEKELKLLEDFACPGCGSCA 192
D+PA+ ++GGPML G+++G+ V T V++ +K G+M+E+E E G C
Sbjct: 140 DLPAVMVTGGPMLNGKYRGQDVGSGTHVWKFEEDLKTGRMTEEECFFAEGCMARSNGHCM 199
Query: 193 GMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKLVEEDLKPSDILTPE 252
M TA+TM L EALG+ LP + PAV + R+ A+ G +I+ +VEE+L+PS ILT E
Sbjct: 200 TMGTASTMACLAEALGMQLPGSAAWPAVDSRRMETAQAAGQRIVGMVEEELRPSRILTRE 259
Query: 253 AFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFDEISEKTPTLVKISPAGKHFVL 312
AFE+A+ V+ A+GGSTN V+HL+AIA GV L+L FDE++ PTLV + P+GK+ +
Sbjct: 260 AFENAVRVNAAIGGSTNAVIHLLAIAGRVGVDLSLRDFDELARAVPTLVNLMPSGKYLME 319
Query: 313 DLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVGE-----------------LLRDVSVL 355
D AGG+ A++ L GL+H +ITV+ +T+ E + D
Sbjct: 320 DFCYAGGLPAVLAELLGGGLLHGSQITVTGRTIAENNTGSTDNTGNTGNTERVGSDPDPD 379
Query: 356 RD-DVIRPVTRPYLSRG-GLMILYGSLAPKGAVLKVSAI-PDIETFEGEARVFDCEEDAV 412
D DVI + P+ G G+ +L G+L P GAV+K SA P + T G ARVFD E A
Sbjct: 380 PDFDVITRLDAPFQPAGTGIAVLRGNLCPDGAVIKQSAASPHLLTHRGPARVFDSPE-AY 438
Query: 413 KAILSG---DIEKGDVVVIRYEGPKGGPGMREML-APTSAIAGMGLDRDVALVTDGRFSG 468
+ DI++ V+VIR GPKG PGM E+ P A +D+ V DGR SG
Sbjct: 439 HEVADDPDLDIDENTVIVIRNAGPKGYPGMPEVANVPLPAKLLKAGVKDMVRVCDGRMSG 498
Query: 469 ATRGLSIGHVSPEAAEGGPIALVEDGDLIRIDVKAKRIDLLVDEEELKERKAKWK-PKVK 527
G + HV+PEAA GGP+ALV DGD + +DV + + L VD+ EL R+ W+ P +
Sbjct: 499 TGYGTVVLHVAPEAAVGGPLALVHDGDPVVLDVPHRTLRLDVDDAELTRRRRAWRAPAER 558
Query: 528 EVKGYLKRYSSLVTSANTGAVF 549
GY Y+ V A+ GA F
Sbjct: 559 HAGGYAWLYTQNVEQADRGADF 580
>sp|Q9XBI3|ILVD_BACCE DIHYDROXY-ACID DEHYDRATASE (DAD) >gi|4584119|emb|CAB40615.1|
(AJ007788) dihydroxy-acid dehydratase [Bacillus cereus]
Length = 357
Score = 351 bits (890), Expect = 2e-95
Identities = 178/353 (50%), Positives = 249/353 (70%), Gaps = 3/353 (0%)
Query: 200 MNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKLVEEDLKPSDILTPEAFEDAIA 259
MN L E LG++LP NG+ A+ R + KQ ++ L+E D+KP DI+T EA +DA A
Sbjct: 1 MNCLCEVLGLALPGNGSILAIDPRREELIKQAAEKLKILIERDIKPRDIVTEEAIDDAFA 60
Query: 260 VDMALGGSTNTVLHLMAIAREAGVKLTLDTFDEISEKTPTLVKISPAGKHFVLDLYEAGG 319
+DMA+GGSTNTVLH +A+A EAG+ + D +S + P L K+SPA + D+ AGG
Sbjct: 61 LDMAMGGSTNTVLHTLALAHEAGLDYDMSRIDAVSRRVPHLCKVSPASNWHMEDIDRAGG 120
Query: 320 VLAIMKRLSEL-GLIHEDRITVSLKTVGELLRDVSVLRDDVIRPVTRPYLSRGGLMILYG 378
+ AI+K +S G++H DRIT + +T+ E + + +VI + P+ GGL IL G
Sbjct: 121 ISAILKEMSRKEGVLHLDRITATGQTLRENIAHAEIKDKEVIHSLENPHSEEGGLRILKG 180
Query: 379 SLAPKGAVLKVSAIPDIETFEGEARVFDCEEDAVKAILSGDIEKGDVVVIRYEGPKGGPG 438
+LA GAV+K S +++ FEG +F+ +++A+ I+ G ++KGDVVVIRYEGP+GGPG
Sbjct: 181 NLAKDGAVIK-SGATEVKRFEGPCVIFNSQDEALAGIMLGKVKKGDVVVIRYEGPRGGPG 239
Query: 439 MREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIGHVSPEAAEGGPIALVEDGDLIR 498
M EMLAPTSAIAGMGL DVAL+TDGRFSGA+RG+S+GH+SPEAA GG IAL+E GD++
Sbjct: 240 MPEMLAPTSAIAGMGLGADVALLTDGRFSGASRGISVGHISPEAAAGGTIALLEQGDIVC 299
Query: 499 IDVKAKRIDLLVDEEELKERKAKWK-PKVKEVKGYLKRYSSLVTSANTGAVFR 550
IDV+ + +++ V +EEL +RK +WK P+ K G+L RY+ +VTSANTGAV +
Sbjct: 300 IDVEERLLEVRVSDEELDKRKKEWKRPEPKVKTGWLGRYAQMVTSANTGAVLK 352
>gb|AAA34568.1| (L13975) dihydroxyacid dehydratase [Saccharomyces cerevisiae]
Length = 371
Score = 272 bits (689), Expect = 6e-72
Identities = 147/361 (40%), Positives = 227/361 (62%), Gaps = 9/361 (2%)
Query: 69 LEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCDKIIPGMLM 128
++F+TIG+ DGI+MG GM+YSL SRE+IADS E ++ A ++D + I SCDK +PG++M
Sbjct: 12 MQFNTIGVSDGISMGTKGMRYSLQSREIIADSFETIMMAQHYDANIAIPSCDKNMPGVMM 71
Query: 129 AMARLDIPAIFISGGPMLPGRFK------GEYVDVKTVFEAVGAVKAGKMSEKELKLLED 182
AM R + P+I + GG +LPG + +D+ + F++ G + + +E+E + + +
Sbjct: 72 AMGRHNRPSIMVYGGTILPGHPTCGSSKISKNIDIVSAFQSYGEYISKQFTEEEREDVVE 131
Query: 183 FACPGCGSCAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKLVEED 242
ACPG GSC GM+TANTM + E L +++ + + PAV ++ G I K +E
Sbjct: 132 HACPGPGSCGGMYTANTMASAAEVLSLTISNSSSFPAVSKEKLAECDNIGEYIKKTMELG 191
Query: 243 LKPSDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFDEISEKTPTLVK 302
+ P DILT EAFE+AI +A GGSTN VLHL+A+A AGVKL+ D F IS+ TP +
Sbjct: 192 ILPRDILTKEAFENAITYVVATGGSTNAVLHLVAVAHSAGVKLSPDDFPRISDTTPLIGD 251
Query: 303 ISPAGKHFVLDLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVGELLRDVSVLRD--DVI 360
P+GK+ + DL GG +++K L E ++H + +TV+ T+ E + L + ++I
Sbjct: 252 FKPSGKYVMADLINVGGTQSVIKYLYENNMLHGNTMTVTGDTLAERAKKAPSLPEGQEII 311
Query: 361 RPVTRPYLSRGGLMILYGSLAPKGAVLKVSAIPDIETFEGEARVFDCEEDAVKAILSGDI 420
+P++ P + G L ILYGSLAP GAV K++ + F+G ARVF+ E ++A+ G+I
Sbjct: 312 KPLSHPIKANGHLQILYGSLAPGGAVGKITG-KEGTYFKGRARVFEEEGAFIEALERGEI 370
Query: 421 E 421
+
Sbjct: 371 K 371
>sp|P21909|EDD_ZYMMO PHOSPHOGLUCONATE DEHYDRATASE (6-PHOSPHOGLUCONATE DEHYDRATASE)
>gi|95543|pir||C37855 phosphogluconate dehydratase (EC
4.2.1.12) - Zymomonas mobilis >gi|155592|gb|AAA27693.1|
(M60615) 6-phosphogluconate dehydratase [Zymomonas
mobilis] >gi|11095426|gb|AAG29866.1|AF313764_9
(AF313764) phosphogluconate dehydratase [Zymomonas
mobilis]
Length = 583
Score = 246 bits (622), Expect = 4e-64
Identities = 177/549 (32%), Positives = 275/549 (49%), Gaps = 41/549 (7%)
Query: 7 KKGIERAPHRALFKAMGLTDEELDKPL--------IGIVNSFNELIPGHIHLRRIAEAVK 58
+KG++R A G DKP IG+V S+N+++ H R E +K
Sbjct: 35 EKGVDRPNLSCSNLAHGFAAMNGDKPALRDFNRMNIGVVTSYNDMLSAHEPYYRYPEQMK 94
Query: 59 TGVRMSGGTPLEFSTI-GICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIA 117
R G T + +CDG+ G GM+ SL SR++IA + + F+G ++
Sbjct: 95 VFAREVGATVQVAGGVPAMCDGVTQGQPGMEESLFSRDVIALATSVSLSHGMFEGAALLG 154
Query: 118 SCDKIIPGMLMAMARLD-IPAIFISGGPMLPGRFKGEYVDVKTVFEAVGAVKAGKMSEKE 176
CDKI+PG+LM R +P I + GPM G E + ++ ++ GK+ +KE
Sbjct: 155 ICDKIVPGLLMGALRFGHLPTILVPSGPMTTGIPNKEKIRIRQLYAQ------GKIGQKE 208
Query: 177 LKLLEDFACPGCGSCAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIM 236
L +E G+C TANT + E LG+ +P + R + + ++
Sbjct: 209 LLDMEAACYHAEGTCTFYGTANTNQMVMEVLGLHMPGSAFVTPGTPLRQALTRAAVHRVA 268
Query: 237 KL--VEEDLKP-SDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFDEI 293
+L +D +P I+ ++ +AI +A GGSTN +H+ AIAR AGV + + F ++
Sbjct: 269 ELGWKGDDYRPLGKIIDEKSIVNAIVGLLATGGSTNHTMHIPAIARAAGVIVNWNDFHDL 328
Query: 294 SEKTPTLVKISPAGKHFVLDLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVGE-----L 348
SE P + +I P G + + AGG+ ++K L L++ D T++ + E
Sbjct: 329 SEVVPLIARIYPNGPRDINEFQNAGGMAYVIKELLSANLLNRDVTTIAKGGIEEYAKAPA 388
Query: 349 LRDVSVL---------RDDVIRPVTRPYLSRGGLMILYGSLAPKGAVLKVSAI-PDIETF 398
L D L D ++RPV+ P+ GGL +L G+L A+ K SA+ P T
Sbjct: 389 LNDAGELVWKPAGEPGDDTILRPVSNPFAKDGGLRLLEGNLG--RAMYKASAVDPKFWTI 446
Query: 399 EGEARVFDCEEDAVKAILSGDIEKGDVVVIRYEGPKGGPGMREMLAPTSAIAGMGLDR-- 456
E RVF ++D KA +G++ K +VV+R++GP+ GM E+ T A+ G+ D
Sbjct: 447 EAPVRVFSDQDDVQKAFKAGELNKDVIVVVRFQGPRAN-GMPELHKLTPAL-GVLQDNGY 504
Query: 457 DVALVTDGRFSGATRGLSIG-HVSPEAAEGGPIALVEDGDLIRIDVKAKRIDLLVDEEEL 515
VALVTDGR SGAT + + HVSPEA GG I + DGD++RI V+ +++ LV +E
Sbjct: 505 KVALVTDGRMSGATGKVPVALHVSPEALGGGAIGKLRDGDIVRISVEEGKLEALVPADEW 564
Query: 516 KERKAKWKP 524
R KP
Sbjct: 565 NARPHAEKP 573
>pir||G83246 phosphogluconate dehydratase PA3194 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9949313|gb|AAG06582.1|AE004743_5 (AE004743)
phosphogluconate dehydratase [Pseudomonas aeruginosa]
Length = 608
Score = 245 bits (620), Expect = 7e-64
Identities = 170/564 (30%), Positives = 285/564 (50%), Gaps = 58/564 (10%)
Query: 4 DVIKKGIERAPHRALFK---------AMGLTDEE----LDKPLIGIVNSFNELIPGHIHL 50
++++ + PHR A G +D++ +++ + IV+++N+++ H
Sbjct: 25 EMVRAAASKGPHRGTLPCGNLAHGVAACGESDKQTLRLMNQANVAIVSAYNDMLSAHQPF 84
Query: 51 RRIAEAVKTGV-------RMSGGTPLEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEA 103
R +K + + +GG P +CDG+ G GM+ SL SR++IA S
Sbjct: 85 ERFPGLIKQALHEIGSVGQFAGGVP------AMCDGVTQGEPGMELSLASRDVIAMSTAI 138
Query: 104 VVRAYNFDGIVMIASCDKIIPGMLMAMARLD-IPAIFISGGPMLPGRFKGEYVDVKTVFE 162
+ FD + + CDKI+PG+L+ R +P +F+ GPM G E V+ +F
Sbjct: 139 ALSHNMFDAALCLGVCDKIVPGLLIGSLRFGHLPTVFVPAGPMPTGISNKEKAAVRQLFA 198
Query: 163 AVGAVKAGKMSEKELKLLEDFACPGCGSCAGMFTANTMNALTEALGISLPWNGTAPAVYA 222
GK + +EL E + G+C TANT L E +G+ LP
Sbjct: 199 E------GKATREELLASEMASYHAPGTCTFYGTANTNQLLVEVMGLHLPGASFVNPNTP 252
Query: 223 HRIRIAKQTGMQIMKLVEED---LKPSDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAR 279
R + ++ Q +L E+ + ++I+ +A +++ +A GGSTN LHL+AIA+
Sbjct: 253 LRDELTREAARQASRLTPENGNYVPMAEIVDEKAIVNSVVALLATGGSTNHTLHLLAIAQ 312
Query: 280 EAGVKLTLDTFDEISEKTPTLVKISPAGKHFVLDLYEAGGVLAIMKRLSELGLIHEDRIT 339
AG++LT E+S PTL +I P G+ + AGG+ ++++L + GL+HED T
Sbjct: 313 AAGIQLTWQDMSELSHVVPTLARIYPNGQADINHFQAAGGMSFLIRQLLDGGLLHEDVQT 372
Query: 340 VSLKTVGELLRDVSV--------------LRDDVIRPVTRPYLSRGGLMILYGSLAPKGA 385
V+ + R+ + L + ++RP+ +P+ + GGL ++ G+L
Sbjct: 373 VAGPGLRRYTREPFLEDGRLVWREGPERSLDEAILRPLDKPFSAEGGLRLMEGNLG--RG 430
Query: 386 VLKVSAI-PDIETFEGEARVFDCEEDAVKAILSGDIEKGDVVVIRYEGPKGGPGMREMLA 444
V+KVSA+ P+ + E R+F + A +G++E+ V V+R++GP+ GM E L
Sbjct: 431 VMKVSAVAPEHQVVEAPVRIFHDQASLAAAFKAGELERDLVAVVRFQGPRAN-GMPE-LH 488
Query: 445 PTSAIAGMGLDR--DVALVTDGRFSGATRGLSIG-HVSPEAAEGGPIALVEDGDLIRIDV 501
+ G+ DR VALVTDGR SGA+ + HVSPEA GGP+A + DGD +R+D
Sbjct: 489 KLTPFLGVLQDRGFKVALVTDGRMSGASGKVPAAIHVSPEAIAGGPLARLRDGDRVRVDG 548
Query: 502 KAKRIDLLVDEEELKERKAKWKPK 525
+ +LVD+ E + R + P+
Sbjct: 549 VNGELRVLVDDAEWQARSLEPAPQ 572
>sp|P31961|EDD_PSEAE PHOSPHOGLUCONATE DEHYDRATASE (6-PHOSPHOGLUCONATE DEHYDRATASE)
>gi|430852|gb|AAA03487.1| (M74256) 6-phosphogluconate
dehydratase [Pseudomonas aeruginosa]
Length = 610
Score = 242 bits (611), Expect = 8e-63
Identities = 172/566 (30%), Positives = 288/566 (50%), Gaps = 60/566 (10%)
Query: 4 DVIKKGIERAPHRALFK---------AMGLTDEE----LDKPLIGIVNSFNELIPGHIHL 50
++++ + PHR A G +D++ +++ + IV+++N+++ H +
Sbjct: 25 EMVRAAASKGPHRGTLPCGNLAHGVAACGESDKQTLRLMNQANVAIVSAYNDMLSAHQPV 84
Query: 51 RR-IAEAVKTGV--------RMSGGTPLEFSTIGICDGIAMGHGGMKYSLPSRELIADSI 101
R +K G ++GG P +CDG+ G GM+ SL SR++IA S
Sbjct: 85 RAPFRGLIKPGACTRSVRSASVAGGVP------AMCDGVTQGEPGMELSLASRDVIAMST 138
Query: 102 EAVVRAYNFDGIVMIASCDKIIPGMLMAMARLDIPAIFISGGPMLPGRFKGEYVDVKTVF 161
+ FD + + CDKI+PG+L A + +P +F+ GGPM G E V+ +F
Sbjct: 139 AIALSHNMFDAALCLGVCDKIVPGLLSAASFGHLPTVFVPGGPMPTGISNKEKAAVRQLF 198
Query: 162 EAVGAVKAGKMSEKELKLLEDFACPGCGSCAGMFTANTMNA-LTEALGISLPWNGTAPAV 220
GK + +EL E + G+C TANT L E +G+ LP
Sbjct: 199 AE------GKATREELLASEMASYHAPGTCTFYGTANTNQVRLVEVMGLHLPGASFVNPN 252
Query: 221 YAHRIRIAKQTGMQIMKLVEED---LKPSDILTPEAFEDAIAVDMALGGSTNTVLHLMAI 277
R ++++ Q +L E+ + ++I+ +A +++ +A GGSTN LHL+AI
Sbjct: 253 TPLRDELSREAARQASRLTPENGNYVPMAEIVDEKAIVNSVVALLATGGSTNHTLHLLAI 312
Query: 278 AREAGVKLTLDTFDEISEKTPTLVKISPAGKHFVLDLYEAGGVLAIMKRLSELGLIHEDR 337
A+ AG++LT E+S PTL +I P G+ + AGG+ ++++L + GL+HED
Sbjct: 313 AQAAGIQLTWQDMSELSHVVPTLARIYPNGQADINHFQAAGGMSFLIRQLLDGGLLHEDV 372
Query: 338 ITVSLKTVGELLRDVSV--------------LRDDVIRPVTRPYLSRGGLMILYGSLAPK 383
TV+ + R+ + L + ++RP+ +P+ + GGL ++ G+L
Sbjct: 373 QTVAGPGLRRYTREPFLEDGRLVWREGPERSLDEAILRPLDKPFSAEGGLRLMEGNLG-- 430
Query: 384 GAVLKVSAI-PDIETFEGEARVFDCEEDAVKAILSGDIEKGDVVVIRYEGPKGGPGMREM 442
V+KVSA+ P+ + E R+F + A +G++E+ V V+R++GP+ GM E
Sbjct: 431 RGVMKVSAVAPEHQVVEAPVRIFHDQASLAAAFKAGELERDLVAVVRFQGPRAN-GMPE- 488
Query: 443 LAPTSAIAGMGLDR--DVALVTDGRFSGATRGLSIG-HVSPEAAEGGPIALVEDGDLIRI 499
L + G+ DR VALVTDGR SGA+ + HVSPEA GGP+A + DGD +R+
Sbjct: 489 LHKLTPFLGVLQDRGFKVALVTDGRMSGASGKVPAAIHVSPEAIAGGPLARLRDGDRVRV 548
Query: 500 DVKAKRIDLLVDEEELKERKAKWKPK 525
D + +LVD+ E + R + P+
Sbjct: 549 DGVNGELRVLVDDAEWQARSLEPAPQ 574
>pir||A81088 phosphogluconate dehydratase NMB1393 [imported] - Neisseria
meningitidis (group B strain MD58)
>gi|7226632|gb|AAF41757.1| (AE002488) phosphogluconate
dehydratase [Neisseria meningitidis MC58]
Length = 611
Score = 239 bits (604), Expect = 5e-62
Identities = 167/543 (30%), Positives = 277/543 (50%), Gaps = 36/543 (6%)
Query: 32 PLIGIVNSFNELIPGHIHLRRIAEAVKTGVRMSGGTP-LEFSTIGICDGIAMGHGGMKYS 90
P +GI+ ++N+++ H + + +K + +G T + T +CDGI G+ GM+ S
Sbjct: 72 PNLGIITAYNDMVSAHQPFKDFPDQIKDEAQKNGATAQVAGGTPAMCDGITQGYAGMELS 131
Query: 91 LPSRELIADSIEAVVRAYNFDGIVMIASCDKIIPGMLM-AMARLDIPAIFISGGPMLPGR 149
L SR++IA S + FDG + + CDKI+PG+++ A++ IP IF+ GPM G
Sbjct: 132 LFSRDVIAMSTAIGLSHQMFDGSLFMGVCDKIVPGLMIGALSFGHIPGIFVPAGPMSSGI 191
Query: 150 FKGEYVDVKTVFEAVGAVKAGKMSEKELKLLEDFACPGCGSCAGMFTANTMNALTEALGI 209
E + +F GK+ EL E + G+C TAN+ + E +G+
Sbjct: 192 GNKEKARTRQLFAE------GKVGRNELLKSEMGSYHSPGTCTFYGTANSNQMMMEMMGV 245
Query: 210 SLPWNGTAPAVYAHRIRIAKQTGMQIMKLVEED-LKP-SDILTPEAFEDAIAVDMALGGS 267
LP R + + + + ++ +KP ++LT ++F +A+ MA GGS
Sbjct: 246 HLPAAAFVHPYTDLREALTRYAAGHLARGIKNGTIKPLGEMLTEKSFINALIGLMATGGS 305
Query: 268 TNTVLHLMAIAREAGVKLTLDTFDEISEKTPTLVKISPAGKHFVLDLYEAGGVLAIMKRL 327
TN +HL+A+AR AGV L D FDEIS P L+++ P GK V AGG+ +++ L
Sbjct: 306 TNHTMHLVAMARAAGVILNWDDFDEISSIIPLLIRVYPNGKADVNHFTAAGGLPFVIREL 365
Query: 328 SELGLIHEDRITVSLKTVGELLRDVSVL--------------RDDVIRPVTRPYLSRGGL 373
GL+H+D TV + ++ ++ DD++R P+ GGL
Sbjct: 366 LNAGLLHDDVDTVVGHGMRHYTKEPFLIDGKLEWREAPETSGNDDILRKADNPFSPDGGL 425
Query: 374 MILYGSLAPKGAVLKVSAIPD-IETFEGEARVFDCEEDAVKAILSGDIEKGDVVVIRYEG 432
++ G++ V+KVSA+ + E A VF+ + + + A G++E+ V V+RY+G
Sbjct: 426 RLMKGNIG--RGVIKVSAVREGCRIIEAPAIVFNDQREVLAAFERGELERDFVCVVRYQG 483
Query: 433 PK--GGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIG-HVSPEAAEGGPIA 489
P+ G P + ++ P + G VAL+TDGR SGA+ + H++PEA GG IA
Sbjct: 484 PRANGMPELHKLTPPLGILQDRGF--KVALLTDGRMSGASGKVPASIHMTPEALMGGNIA 541
Query: 490 LVEDGDLIRIDVKAKRIDLLVDEEELKERKAKWKPKVKEVKG----YLKRYSSLVTSANT 545
+ GDLIR D + +++L++E E R+ + +G + S+ +SA T
Sbjct: 542 KIRTGDLIRFDSVSGELNVLINETEWNAREVESIDLGANQQGCGRELFANFRSMTSSAET 601
Query: 546 GAV 548
GA+
Sbjct: 602 GAM 604
>pir||C82727 6-phosphogluconate dehydratase XF1062 [imported] - Xylella
fastidiosa (strain 9a5c)
>gi|9106009|gb|AAF83872.1|AE003943_3 (AE003943)
6-phosphogluconate dehydratase [Xylella fastidiosa]
Length = 630
Score = 239 bits (604), Expect = 5e-62
Identities = 167/527 (31%), Positives = 267/527 (49%), Gaps = 37/527 (7%)
Query: 19 FKAMGLTDEELDK----PLIGIVNSFNELIPGHIHLRRIAEAVKTGVRMSGGTPLEFSTI 74
F A G D+E + P +GI+ ++N+++ H + ++ R+ G T ++
Sbjct: 51 FAACGTADKERLREAITPNLGIITAYNDMLSAHQPFEHYPDIIRNTARVLGATAQVAGSV 110
Query: 75 -GICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCDKIIPGMLM-AMAR 132
+CDG+ G GM+ SL SR+ IA S + FD + + CDKI+PG+L+ A+A
Sbjct: 111 PAMCDGVTQGRAGMELSLFSRDNIAQSTAIGLSHDMFDAAIYLGVCDKIVPGLLIGALAF 170
Query: 133 LDIPAIFISGGPMLPGRFKGEYVDVKTVFEAVGAVKAGKMSEKELKLLEDFACPGCGSCA 192
+PA F+ GPM G + +++ + A G+ + EL +E + G+C
Sbjct: 171 GHLPAAFVPAGPMPSGIPNKQKAEIRERYAA------GQATRAELLAVEAASYHAPGTCT 224
Query: 193 GMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKLVE--EDLKPSDILT 250
TAN+ L EA+G+ LP R + + +++ + +D +P L
Sbjct: 225 FYGTANSNQVLLEAMGVQLPGASFVSPGTPLREALTQAATERVLHITALGQDFRPIGRLI 284
Query: 251 PE-AFEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFDEISEKTPTLVKISPAGKH 309
E A +AI MA GGSTN +H +A+AR AG+ LT D D IS+ P L ++ P G+
Sbjct: 285 DERAIVNAIVALMATGGSTNHTIHWIAVARAAGILLTWDDMDRISQTVPLLARVYPNGEA 344
Query: 310 FVLDLYEAGGVLAIMKRLSELGLIHEDRITVSL--------------KTVGELLRDVSVL 355
V + AGG + + L + GL+++D T+ T+G +
Sbjct: 345 DVNRFHAAGGTAFVFRELMDAGLMYDDLPTIVAGGMRAYTQEPHLHHGTLGYNPSPTTST 404
Query: 356 RDDVIRPVTRPYLSRGGLMILYGSLAPKGAVLKVSAI-PDIETFEGEARVFDCEEDAVKA 414
V+RPVT P+ +GGL +L G+L A++K+SA+ P+ E A V D + K
Sbjct: 405 DASVVRPVTHPFEPQGGLRLLRGNLG--RALIKLSAVKPEYRAIEAPAVVIDTPQTLHKL 462
Query: 415 ILSGDIEKGDVVVIRYEGPKGGPGMREM--LAPTSAIAGMGLDRDVALVTDGRFSGATRG 472
+G + K ++V+RY+GP+ GM E+ LAP + R +ALVTDGR SGA+
Sbjct: 463 HAAGALPKDFILVVRYQGPRAN-GMPELHSLAPLLGLL-QNQGRRIALVTDGRLSGASGK 520
Query: 473 LSIG-HVSPEAAEGGPIALVEDGDLIRIDVKAKRIDLLVDEEELKER 518
H++PEAA GGPI + +GDL+R+D +A ++ LV E + R
Sbjct: 521 FPAAIHLTPEAARGGPIGRIREGDLLRLDGEAGILEALVPTTEWETR 567
>pir||F81854 phosphogluconate dehydratase (EC 4.2.1.12) NMA1610 [imported] -
Neisseria meningitidis (group A strain Z2491)
>gi|7380252|emb|CAB84838.1| (AL162756) phosphogluconate
dehydratase [Neisseria meningitidis Z2491]
Length = 637
Score = 238 bits (602), Expect = 9e-62
Identities = 166/543 (30%), Positives = 277/543 (50%), Gaps = 36/543 (6%)
Query: 32 PLIGIVNSFNELIPGHIHLRRIAEAVKTGVRMSGGTP-LEFSTIGICDGIAMGHGGMKYS 90
P +GI+ ++N+++ H + + +K + +G T + T +CDGI G+ GM+ S
Sbjct: 98 PNLGIITAYNDMVSAHQPFKDFPDQIKDEAQKNGATAQVAGGTPAMCDGITQGYAGMELS 157
Query: 91 LPSRELIADSIEAVVRAYNFDGIVMIASCDKIIPGMLM-AMARLDIPAIFISGGPMLPGR 149
L SR++IA S + FDG + + CDKI+PG+++ A++ IP IF+ GPM G
Sbjct: 158 LFSRDVIAMSTAIGLSHQMFDGSLFMGVCDKIVPGLMIGALSFGHIPGIFVPAGPMSSGI 217
Query: 150 FKGEYVDVKTVFEAVGAVKAGKMSEKELKLLEDFACPGCGSCAGMFTANTMNALTEALGI 209
E + +F GK+ EL E + G+C TAN+ + E +G+
Sbjct: 218 GNKEKARTRQLFAE------GKVGRDELLKSEMGSYHSPGTCTFYGTANSNQMMMEMMGV 271
Query: 210 SLPWNGTAPAVYAHRIRIAKQTGMQIMKLVEED-LKP-SDILTPEAFEDAIAVDMALGGS 267
LP R + + + + ++ +KP ++LT ++F +A+ MA GGS
Sbjct: 272 HLPAAAFVHPYTDLREALTRYAAGHLARGIKNGTIKPLGEMLTEKSFINALIGLMATGGS 331
Query: 268 TNTVLHLMAIAREAGVKLTLDTFDEISEKTPTLVKISPAGKHFVLDLYEAGGVLAIMKRL 327
TN +HL+A+AR AGV L D FDEIS P L+++ P GK V AGG+ +++ L
Sbjct: 332 TNHTMHLVAMARAAGVILNWDDFDEISSIIPLLIRVYPNGKADVNHFTAAGGLPFVIREL 391
Query: 328 SELGLIHEDRITVSLKTVGELLRDVSVL--------------RDDVIRPVTRPYLSRGGL 373
GL+H+D T+ + ++ ++ DD++R P+ GGL
Sbjct: 392 LNAGLLHDDVDTIVGHGMRHYTKEPFLIDGKLEWREAPETSGNDDILRKADNPFSPDGGL 451
Query: 374 MILYGSLAPKGAVLKVSAIPD-IETFEGEARVFDCEEDAVKAILSGDIEKGDVVVIRYEG 432
++ G++ V+KVSA+ + E A VF+ + + + A G++E+ V V+RY+G
Sbjct: 452 RLMKGNIG--RGVIKVSAVREGCRIIEAPAIVFNDQREVLAAFERGELERDFVCVVRYQG 509
Query: 433 PK--GGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIG-HVSPEAAEGGPIA 489
P+ G P + ++ P + G VAL+TDGR SGA+ + H++PEA GG IA
Sbjct: 510 PRANGMPELHKLTPPLGILQDRGF--KVALLTDGRMSGASGKVPASIHMTPEALMGGNIA 567
Query: 490 LVEDGDLIRIDVKAKRIDLLVDEEELKERKAKWKPKVKEVKG----YLKRYSSLVTSANT 545
+ GDLIR D + +++L++E E R+ + +G + S+ +SA T
Sbjct: 568 KIRTGDLIRFDSVSGELNVLINETEWNAREVESIDLGANQQGCGRELFANFRSMTSSAET 627
Query: 546 GAV 548
GA+
Sbjct: 628 GAM 630
>sp|P77596|YAGF_ECOLI HYPOTHETICAL 69.4 KD PROTEIN IN PERR-ARGF INTERGENIC REGION
>gi|7436857|pir||E64752 probable dihydroxy-acid
dehydratase yagF - Escherichia coli
>gi|1552838|gb|AAB08690.1| (U70214) similar to E. coli
YjhG [Escherichia coli] >gi|1786464|gb|AAC73372.1|
(AE000134) putative dehydratase [Escherichia coli K12]
Length = 655
Score = 235 bits (594), Expect = 8e-61
Identities = 168/495 (33%), Positives = 247/495 (48%), Gaps = 50/495 (10%)
Query: 46 GHIHLRRIAEAVKTGVRMSGGTPLEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVV 105
GH + +A + +GG P CDG + G GM SLP R A ++
Sbjct: 88 GHWEIGMQMQAAAKEITRNGGIPFAAFVSDPCDGRSQGTHGMFDSLPYRNDAAIVFRRLI 147
Query: 106 RAY-NFDGIVMIASCDKIIPGMLMAMARL-DIPAIFISGGPMLPGRFKGEYVDVKTVFEA 163
R+ ++ +A+CDK +P ++A+A + D+P I + GG LP TV E
Sbjct: 148 RSLPTRRAVIGVATCDKGLPATMIALAAMHDLPTILVPGGATLP----------PTVGED 197
Query: 164 VGAVKA--GKMSEKELKLLE--DFACPGC----GSCAGMFTANTMNALTEALGISLPWNG 215
G V+ + + EL L E + C C G C + TA T + EALG++LP +
Sbjct: 198 AGKVQTIGARFANHELSLQEAAELGCRACASPGGGCQFLGTAGTSQVVAEALGLALPHSA 257
Query: 216 TAPAVYAHRIRIAKQTGMQIMKLVEEDLKPSDILTPEAFEDAIAVDMALGGSTNTVLHLM 275
AP+ A + IA+Q+ + +L + DIL+ +A E+A+ + A GGSTN +LH+
Sbjct: 258 LAPSGQAVWLEIARQSARAVSELDSRGITTRDILSDKAIENAMVIHAAFGGSTNLLLHIP 317
Query: 276 AIAREAGVKL-TLDTFDEISEKTPTLVKISPAGK--HFVLDLYEAGGVLAIMKRLSELGL 332
AIA AG + ++ + I+ K P LV + P G H + + AGGV +M L +LGL
Sbjct: 318 AIAHAAGCTIPDVEHWTRINRKVPRLVSVLPNGPDYHPTVRAFLAGGVPEVMLHLRDLGL 377
Query: 333 IHEDRITVSLKTVGE-----------------LLRDVSVLRDDVIRPVTRPYLSRGGLMI 375
+H D +TV+ +TVGE L V DDVI P + +
Sbjct: 378 LHLDAMTVTGQTVGENLEWWQASERRARFRQCLREQDGVEPDDVILPPEKAKAKGLTSTV 437
Query: 376 LY--GSLAPKGAVLKVSAIPDIETFE-------GEARVFDCEEDAVKAILSGDIEKGDVV 426
+ G++AP+G+V+K +AI E G RVF E A+KAI +I +GD++
Sbjct: 438 CFPTGNIAPEGSVIKATAIDPSVVGEDGVYHHTGRVRVFVSEAQAIKAIKREEIVQGDIM 497
Query: 427 VIRYEGPKGGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIGHVSPEAAEGG 486
V+ GP G GM E TSA+ + + V+L+TD RFSG + G GHVSPEA GG
Sbjct: 498 VVIGGGP-SGTGMEETYQLTSALKHISWGKTVSLITDARFSGVSTGACFGHVSPEALAGG 556
Query: 487 PIALVEDGDLIRIDV 501
PI + D D+I I V
Sbjct: 557 PIGKLRDNDIIEIAV 571
>sp|P25530|EDD_ECOLI PHOSPHOGLUCONATE DEHYDRATASE (6-PHOSPHOGLUCONATE DEHYDRATASE)
>gi|421150|pir||S35911 phosphogluconate dehydratase (EC
4.2.1.12) - Escherichia coli >gi|395403|emb|CAA45221.1|
(X63694) phosphogluconate dehydratase [Escherichia coli]
>gi|1736494|dbj|BAA15659.1| (D90828) Phosphogluconate
dehydratase (EC 4.2.1.12) [Escherichia coli]
>gi|1788157|gb|AAC74921.1| (AE000279) 6-phosphogluconate
dehydratase [Escherichia coli K12]
Length = 603
Score = 235 bits (592), Expect = 1e-60
Identities = 164/517 (31%), Positives = 265/517 (50%), Gaps = 49/517 (9%)
Query: 34 IGIVNSFNELIPGHIHLRRIAEAVKTGV-------RMSGGTPLEFSTIGICDGIAMGHGG 86
I I+ S+N+++ H E ++ + +++GG P +CDG+ G G
Sbjct: 68 IAIITSYNDMLSAHQPYEHYPEIIRKALHEANAVGQVAGGVP------AMCDGVTQGQDG 121
Query: 87 MKYSLPSRELIADSIEAVVRAYNFDGIVMIASCDKIIPGMLMAMARLD-IPAIFISGGPM 145
M+ SL SRE+IA S + FDG + + CDKI+PG+ MA +PA+F+ GPM
Sbjct: 122 MELSLLSREVIAMSAAVGLSHNMFDGALFLGVCDKIVPGLTMAALSFGHLPAVFVPSGPM 181
Query: 146 LPGRFKGEYVDVKTVFEAVGAVKAGKMSEKELKLLEDFACPGCGSCAGMFTANTMNALTE 205
G E V ++ ++ GK+ L E + G+C TANT + E
Sbjct: 182 ASGLPNKEKVRIRQLYAE------GKVDRMALLESEAASYHAPGTCTFYGTANTNQMVVE 235
Query: 206 ALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKLV---EEDLKPSDILTPEAFEDAIAVDM 262
+G+ LP + R + Q+ ++ E + ++ + + I +
Sbjct: 236 FMGMQLPGSSFVHPDSPLRDALTAAAARQVTRMTGNGNEWMPIGKMIDEKVVVNGIVALL 295
Query: 263 ALGGSTNTVLHLMAIAREAGVKLTLDTFDEISEKTPTLVKISPAGKHFVLDLYEAGGVLA 322
A GGSTN +HL+A+AR AG+++ D F ++S+ P + ++ P G + AGGV
Sbjct: 296 ATGGSTNHTMHLVAMARAAGIQINWDDFSDLSDVVPLMARLYPNGPADINHFQAAGGVPV 355
Query: 323 IMKRLSELGLIHEDRITV-----SLKTVGELLRDVSV---------LRDDVIRPVTRPYL 368
+++ L + GL+HED TV S T+ L + + L +VI +P+
Sbjct: 356 LVRELLKAGLLHEDVNTVAGFGLSRYTLEPWLNNGELDWREGAEKSLDSNVIASFEQPFS 415
Query: 369 SRGGLMILYGSLAPKGAVLKVSAIP-DIETFEGEARVFDCEEDAVKAILSGDIEKGDVVV 427
GG +L G+L AV+K SA+P + + E A VF+ + D + A +G +++ VVV
Sbjct: 416 HHGGTKVLSGNLG--RAVMKTSAVPVENQVIEAPAVVFESQHDVMPAFEAGLLDRDCVVV 473
Query: 428 IRYEGPK--GGPGMREMLAPTSAIAGMGLDR--DVALVTDGRFSGATRGL-SIGHVSPEA 482
+R++GPK G P + +++ P G+ LDR +ALVTDGR SGA+ + S HV+PEA
Sbjct: 474 VRHQGPKANGMPELHKLMPP----LGVLLDRCFKIALVTDGRLSGASGKVPSAIHVTPEA 529
Query: 483 AEGGPIALVEDGDLIRIDVKAKRIDLLVDEEELKERK 519
+GG +A V DGD+IR++ + + LLVDE EL R+
Sbjct: 530 YDGGLLAKVRDGDIIRVNGQTGELTLLVDEAELAARE 566
>pir||A42986 phosphogluconate dehydratase (EC 4.2.1.12) - Escherichia coli
>gi|145826|gb|AAA23722.1| (M87458) 6-phosphogluconate
dehydratase [Escherichia coli]
Length = 602
Score = 233 bits (589), Expect = 3e-60
Identities = 170/526 (32%), Positives = 270/526 (51%), Gaps = 68/526 (12%)
Query: 34 IGIVNSFNELIPGHIHLRRIAEAVKTGV-------RMSGGTPLEFSTIGICDGIAMGHGG 86
I I+ S+N+++ H E ++ + +++GG P +CDG+ G G
Sbjct: 68 IAIITSYNDMLSAHQPYEHYPEIIRKALHEANAVGQVAGGVP------AMCDGVTQGQDG 121
Query: 87 MKYSLPSRELIADSIEAVVRAYNFDGIVMIASCDKIIPGMLMAMARLD-IPAIFISGGPM 145
M+ SL SRE+IA S + FDG + + CDKI+PG+ MA +PA+F+ GPM
Sbjct: 122 MELSLLSREVIAMSAAVGLSHNMFDGALFLGVCDKIVPGLTMAALSFGHLPAVFVPSGPM 181
Query: 146 LPGRFKGEYVDVKTVFEAVGAVKAGKMSEKELKLLEDFACPGCGSCAGMFTANTMNALTE 205
G E V ++ ++ GK+ L E + G+C TANT + E
Sbjct: 182 ASGLPNKEKVRIRQLYAE------GKVDRMALLESEAASYHAPGTCTFYGTANTNQMVVE 235
Query: 206 ALGISLPWNG------TAPAVYAHRIR-IAKQTG-----MQIMKLVEEDLKPSDILTPEA 253
+G+ LP + A+ A R + + TG M I K+++E +
Sbjct: 236 FMGMQLPGSSFVHPDSACDALTAAAARQVTRMTGNGNEWMPIGKMIDE----------KV 285
Query: 254 FEDAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFDEISEKTPTLVKISPAGKHFVLD 313
+ I +A GGSTN +HL+A+AR AG+++ D F ++S+ P + ++ P G +
Sbjct: 286 VVNGIVALLATGGSTNHTMHLVAMARAAGIQINWDDFSDLSDVVPLMARLYPNGPADINH 345
Query: 314 LYEAGGVLAIMKRLSELGLIHEDRITV-----SLKTVGELLRDVSV---------LRDDV 359
AGGV +++ L + GL+HED TV S T+ L + + L +V
Sbjct: 346 FQAAGGVPVLVRELLKAGLLHEDVNTVAGFGLSRYTLEPWLNNGELDWREGAEKSLDSNV 405
Query: 360 IRPVTRPYLSRGGLMILYGSLAPKGAVLKVSAIP-DIETFEGEARVFDCEEDAVKAILSG 418
I +P+ GG +L G+L AV+K SA+P + + E A VF+ + D + A +G
Sbjct: 406 IASFEQPFSHHGGTKVLSGNLG--RAVMKTSAVPVENQVIEAPAVVFESQHDVMPAFEAG 463
Query: 419 DIEKGDVVVIRYEGPK--GGPGMREMLAPTSAIAGMGLDR--DVALVTDGRFSGATRGL- 473
+++ VVV+R++GPK G P + +++ P G+ LDR +ALVTDGR SGA+ +
Sbjct: 464 LLDRDCVVVVRHQGPKANGMPELHKLMPP----LGVLLDRCFKIALVTDGRLSGASGKVP 519
Query: 474 SIGHVSPEAAEGGPIALVEDGDLIRIDVKAKRIDLLVDEEELKERK 519
S HV+PEA +GG +A V DGD+IR++ + + LLVDE EL R+
Sbjct: 520 SAIHVTPEAYDGGLLAKVRDGDIIRVNGQTGELTLLVDEAELAARE 565
>sp|Q9Z3S0|EDD_RHIME PHOSPHOGLUCONATE DEHYDRATASE (6-PHOSPHOGLUCONATE DEHYDRATASE)
>gi|4210902|gb|AAD12045.1| (AF045609) Edd [Sinorhizobium
meliloti]
Length = 606
Score = 230 bits (581), Expect = 3e-59
Identities = 166/512 (32%), Positives = 260/512 (50%), Gaps = 36/512 (7%)
Query: 32 PLIGIVNSFNELIPGHIHLRRIAEAVKTGVRMSGGTPLEFSTI-GICDGIAMGHGGMKYS 90
P +GI+ S+N+++ H ++ +GG + +CDG+ G GM+ S
Sbjct: 68 PNLGIITSYNDMLSAHQPFETYPALIREAAHEAGGVAQVAGGVPAMCDGVTQGQPGMELS 127
Query: 91 LPSRELIADSIEAVVRAYNFDGIVMIASCDKIIPGMLMAMARLD-IPAIFISGGPMLPGR 149
L SR++IA + + FD V + CDKI+PG+ +A +PA+FI GPM G
Sbjct: 128 LFSRDVIAMAAGIGLSHNMFDAAVYLGVCDKIVPGLAIAALTFGHLPAVFIPAGPMTTGL 187
Query: 150 FKGEYVDVKTVFEAVGAVKAGKMSEKELKLLEDFACPGCGSCAGMFTANTMNALTEALGI 209
E V+ +F GK+ EL E + G G+C TAN+ L E +G
Sbjct: 188 PNDEKAKVRQLFAE------GKVGRDELLEAESKSYHGPGTCTFYGTANSNQMLMEIMGF 241
Query: 210 SLPW----NGTAPAVYAHRIRIAKQTGMQIMKLVEEDLKPSDILTPEAFEDAIAVDMALG 265
LP N P A R A + + I L E +++ + + + A G
Sbjct: 242 HLPGASFINPGTPLRDA-LTREATKRALAITALGNEFTPAGEMIDERSIVNGVVGLHATG 300
Query: 266 GSTNTVLHLMAIAREAGVKLTLDTFDEISEKTPTLVKISPAGKHFVLDLYEAGGVLAIMK 325
GSTN +HL+A+AR AG+ LT E+S+ P L ++ P G V + AGG+ ++
Sbjct: 301 GSTNHTMHLVAMARAAGIVLTWQDISELSDLVPLLARVYPNGLADVNHFHAAGGMGFLIA 360
Query: 326 RLSELGLIHEDRITVSLKTVGELLRDV------SVLRD---------DVIRPVTRPYLSR 370
+L GL+H+D TV + + DV SV R+ V+ V RP+
Sbjct: 361 QLLRKGLLHDDVRTVYGQGLSAYAIDVKLGENGSVKREPAPEASADPKVLATVDRPFQHT 420
Query: 371 GGLMILYGSLAPKGAVLKVSAI-PDIETFEGEARVFDCEEDAVKAILSGDIEKGDVVVIR 429
GGL +L G++ AV+K+SA+ P+ E A++F+ + + A +G +E V V+R
Sbjct: 421 GGLKMLSGNIGK--AVIKISAVKPESHVIEAPAKIFNDQAELNAAFKAGKLEGDFVAVVR 478
Query: 430 YEGPKGGPGMREMLAPTSAIAGMGLDR--DVALVTDGRFSGATRGLSIG-HVSPEAAEGG 486
++GPK GM E L + + G+ DR VA++TDGR SGA+ + HV+PEA EGG
Sbjct: 479 FQGPKAN-GMPE-LHKLTTVLGILQDRGQKVAILTDGRMSGASGKVPAAIHVTPEAKEGG 536
Query: 487 PIALVEDGDLIRIDVKAKRIDLLVDEEELKER 518
PIA +++GD++RID ++++LV++ LK R
Sbjct: 537 PIARIQEGDIVRIDAINGKVEVLVEDIALKTR 568
>gi|10955076 mocB [Agrobacterium tumefaciens] >gi|11268880|pir||T44933
phosphogluconate dehydratase (EC 4.2.1.12) [imported] -
Agrobacterium tumefaciens plasmid pTi15955
>gi|797335|gb|AAB07784.1| (AF242881) mocB [Agrobacterium
tumefaciens]
Length = 606
Score = 228 bits (574), Expect = 2e-58
Identities = 164/541 (30%), Positives = 266/541 (48%), Gaps = 37/541 (6%)
Query: 34 IGIVNSFNELIPGHIHLRRIAEAVKTGVRMSGGTPLEFSTI-GICDGIAMGHGGMKYSLP 92
+GIV S+N+++ H +A+K+ R G T + +CDG+ G GM SL
Sbjct: 70 LGIVTSYNDMLSAHQPYGNYPDAIKSAARSVGATAQVARGVPAMCDGVTQGQPGMDLSLF 129
Query: 93 SRELIADSIEAVVRAYNFDGIVMIASCDKIIPGMLM-AMARLDIPAIFISGGPMLPGRFK 151
SR++IA S + FD V + CDKI+PG+L+ A++ +PA+F+ GPM G
Sbjct: 130 SRDVIAMSTAIALSHNMFDAAVYLGVCDKIVPGLLIGALSFGHLPAVFVPAGPMTSGLSN 189
Query: 152 GEYVDVKTVFEAVGAVKAGKMSEKELKLLEDFACPGCGSCAGMFTANTMNALTEALGISL 211
E ++ + GK+ +L E + G+C TAN+ L E +G+ +
Sbjct: 190 DEKARIRQLSSE------GKIDRPQLLDAEAKSYHSPGTCTFYGTANSNQMLMEIMGLHI 243
Query: 212 PWNGTAPAVYAHRIRIAKQTGMQIMKLVE--EDLKP-SDILTPEAFEDAIAVDMALGGST 268
P + A R + ++ + + L + P I+ A + I +A GGST
Sbjct: 244 PGSSFVNANTPLRDALTREATRRALSLTAGGNNYTPIGHIIDERAVVNGIVGLLATGGST 303
Query: 269 NTVLHLMAIAREAGVKLTLDTFDEISEKTPTLVKISPAGKHFVLDLYEAGGVLAIMKRLS 328
N LH++AIA+ AG+ +T + ++S+ P L ++ P G V + AGG+ +++ L
Sbjct: 304 NHTLHIVAIAQAAGLNVTWEDMSDLSDVVPLLTRVYPNGSADVNHFHAAGGMGLLIRELI 363
Query: 329 ELGLIHEDRITV------SLKTVGELLRDVSVL--------RDDVIRPVTRPYLSRGGLM 374
+ G +HED T+ S L D V V+ PV+ + GGL
Sbjct: 364 DGGFLHEDVKTIWGTGLESYPVEARLAGDELVFEPTPAGSRNPKVLAPVSGAFSPNGGLK 423
Query: 375 ILYGSLAPKGAVLKVSAI-PDIETFEGEARVFDCEEDAVKAILSGDIEKGDVVVIRYEGP 433
+L G++ +V+KVSA+ P+ E ARVF +E+ KA G++E+ + V+R++GP
Sbjct: 424 LLSGNIGK--SVIKVSAVKPENRVVEAPARVFHAQEELQKAFRDGELERDMIAVVRFQGP 481
Query: 434 K--GGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGLSIG-HVSPEAAEGGPIAL 490
+ G P + ++ + G VAL+TDGR SGA+ + H++PEA++GG I+
Sbjct: 482 RSIGMPELHKLTPMLGVLQDRGF--KVALLTDGRMSGASGKVPAAIHITPEASDGGAISR 539
Query: 491 VEDGDLIRIDVKAKRIDLLVDEEELKERKAKWKPKVKEVKG----YLKRYSSLVTSANTG 546
+ DGDLIR+D + L D+EE R + G R SLV+ A+ G
Sbjct: 540 IRDGDLIRLDAIEGTLTYLGDDEEFNSRVPATHDHRPQHYGTGRELFARCRSLVSPADLG 599
Query: 547 A 547
A
Sbjct: 600 A 600
>sp|P39358|YJHG_ECOLI HYPOTHETICAL 70.0 KD PROTEIN IN FECI-FIMB INTERGENIC REGION
>gi|7436858|pir||C65243 hypothetical 70.1 kD protein in
fecI-fimB intergenic region - Escherichia coli (strain
K-12) >gi|2367371|gb|AAC77253.1| (AE000500) putative
dehydratase [Escherichia coli K12]
Length = 655
Score = 218 bits (549), Expect = 2e-55
Identities = 165/530 (31%), Positives = 265/530 (49%), Gaps = 50/530 (9%)
Query: 22 MGLTDEELDKPLIGIVNSFN------------ELIPGHIHLRRIAEAVKTGVRMSGGTPL 69
MG + +ELD+ I ++++ L GH L +A ++ + P
Sbjct: 52 MGWSPDELDRDGILLLSTLGGLRGADGKPVALALHQGHYELDIQMKAAAEVIKANHALPY 111
Query: 70 EFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAY-NFDGIVMIASCDKIIPGMLM 128
CDG G GM SLP R + + ++R+ + ++ +ASCDK +P +M
Sbjct: 112 AVYVSDPCDGRTQGTTGMFDSLPYRNDASMVMRRLIRSLPDAKAVIGVASCDKGLPATMM 171
Query: 129 AMA-RLDIPAIFISGGPMLPGRFKGEYVDVKTVFEAVGAVKA-GKMSEKELKLLEDFACP 186
A+A + +I + + GG LP + + V+T+ GA A G++S ++ + AC
Sbjct: 172 ALAAQHNIATVLVPGGATLPAKDGEDNGKVQTI----GARFANGELSLQDARRAGCKACA 227
Query: 187 GCGS-CAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKLVEEDLKP 245
G C + TA T + E LG+++P + AP+ IA+ + + L ++ +
Sbjct: 228 SSGGGCQFLGTAGTSQVVAEGLGLAIPHSALAPSGEPVWREIARASARAALNLSQKGITT 287
Query: 246 SDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVKL-TLDTFDEISEKTPTLVKIS 304
+ILT +A E+A+ V A GGSTN +LH+ AIA +AG + T+D + I+++ P LV +
Sbjct: 288 REILTDKAIENAMTVHAAFGGSTNLLLHIPAIAHQAGCHIPTVDDWIRINKRVPRLVSVL 347
Query: 305 PAGK--HFVLDLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVGE--------------- 347
P G H ++ + AGGV +M L LGL+HED +TV+ T+ E
Sbjct: 348 PNGPVYHPTVNAFMAGGVPEVMLHLRSLGLLHEDVMTVTGSTLKENLDWWEHSERRQRFK 407
Query: 348 -LLRDVSVLRDDVIRPVTRPYLSRG---GLMILYGSLAPKGAVLKVSAIPD-------IE 396
LL D + D + + +RG + G++AP+G+V+K +AI I
Sbjct: 408 QLLLDQEQINADEVIMSPQQAKARGLTSTITFPVGNIAPEGSVIKSTAIDPSMIDEQGIY 467
Query: 397 TFEGEARVFDCEEDAVKAILSGDIEKGDVVVIRYEGPKGGPGMREMLAPTSAIAGMGLDR 456
+G A+V+ E+ A+ I I+ GD++VI GP G GM E TSA+ + +
Sbjct: 468 YHKGVAKVYLSEKSAIYDIKHDKIKAGDILVIIGVGPSG-TGMEETYQVTSALKHLSYGK 526
Query: 457 DVALVTDGRFSGATRGLSIGHVSPEAAEGGPIALVEDGDLIRIDVKAKRI 506
V+L+TD RFSG + G IGHV PEA GGPI + GDLI I + + +
Sbjct: 527 HVSLITDARFSGVSTGACIGHVGPEALAGGPIGKLRTGDLIEIKIDCREL 576
>pir||G82340 phosphogluconate dehydratase VC0288 [imported] - Vibrio cholerae
(group O1 strain N16961) >gi|9654699|gb|AAF93462.1|
(AE004117) phosphogluconate dehydratase [Vibrio
cholerae]
Length = 618
Score = 215 bits (541), Expect = 1e-54
Identities = 160/505 (31%), Positives = 250/505 (48%), Gaps = 43/505 (8%)
Query: 34 IGIVNSFNELIPGHIHLRRIAEAVKTGV-------RMSGGTPLEFSTIGICDGIAMGHGG 86
+ IV S+N+++ H + + +K + +++GG P +CDG+ G G
Sbjct: 89 VAIVTSYNDMLSAHQPYQHYPDRIKMVLAEYGHTAQVAGGVP------AMCDGVTQGQPG 142
Query: 87 MKYSLPSRELIADSIEAVVRAYNFDGIVMIASCDKIIPGMLM-AMARLDIPAIFISGGPM 145
M SL SR+LIA + + FD +++ CDKI PG LM A++ +P F+ G M
Sbjct: 143 MDMSLFSRDLIAQATALSLSHNVFDATLLLGICDKIAPGQLMGALSYAHLPTAFMPAGLM 202
Query: 146 LPGRFKGEYVDVKTVFEAVGAVKAGKMSEKELKLLEDFACPGCGSCAGMFTANTMNALTE 205
G E VD++ + A G++ + L +E A G+C TANT + E
Sbjct: 203 ATGISNEEKVDIRQKYAA------GEVGKDALLNMECQAYHAPGTCTFYGTANTNQLVFE 256
Query: 206 ALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKLVEEDLKPS---DILTPEAFEDAIAVDM 262
A+G+ LP + A R + ++I + + + ++T ++ + I +
Sbjct: 257 AMGLMLPGSAFVHPHSALRQALNDDATVKIASMTQGSAQYRPLYQVVTEKSLLNGIVALL 316
Query: 263 ALGGSTNTVLHLMAIAREAGVKLTLDTFDEISEKTPTLVKISPAGKHFVLDLYEAGGVLA 322
A GGSTN +H++A+AR AG+ LT ++S+ P L K+ P G + +AGGV A
Sbjct: 317 ASGGSTNHTIHMLAVARAAGILLTWQDISDLSDVVPLLAKVYPNGPADMNAFQQAGGVPA 376
Query: 323 IMKRLSELGLIH----------EDRITVSLKTVGELL-RDVSVLRD-DVIRPVTRPYLSR 370
+MKRL E L+H D++T+ GEL + RD VI + +
Sbjct: 377 LMKRLHESKLLHSDVTPVFGEFRDQLTLPELVDGELCWKACEGTRDAQVIAASGECFQTT 436
Query: 371 GGLMILYGSLAPKGAVLKVSAIPDIE-TFEGEARVFDCEEDAVKAILSGDIEKGDVVVIR 429
GG +L G+L AV+KVSA+ + + E A VF C+ A G++ K +VV+
Sbjct: 437 GGTKMLNGNLG--RAVIKVSAVKEEQRIIEAPAVVFQCQHQVEAAYQRGELNKDCIVVVT 494
Query: 430 YEGP--KGGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGL-SIGHVSPEAAEGG 486
+ GP G P + +++ + G VALVTDGR SGA+ + S HVSPEA GG
Sbjct: 495 HNGPAANGMPELHKLMPILGNVQKAGF--KVALVTDGRLSGASGKIPSAIHVSPEAVRGG 552
Query: 487 PIALVEDGDLIRIDVKAKRIDLLVD 511
I LV DGDL+R+D ++ L D
Sbjct: 553 AIGLVRDGDLLRLDCTTGTLENLTD 577
>pir||S56522 hypothetical protein f655 - Escherichia coli
>gi|537138|gb|AAA97193.1| (U14003) ORF_f655 [Escherichia
coli]
Length = 655
Score = 212 bits (535), Expect = 7e-54
Identities = 163/530 (30%), Positives = 263/530 (48%), Gaps = 50/530 (9%)
Query: 22 MGLTDEELDKPLIGIVNSFN------------ELIPGHIHLRRIAEAVKTGVRMSGGTPL 69
MG + +ELD+ I ++++ L GH L +A ++ + P
Sbjct: 52 MGWSPDELDRDGILLLSTLGGLRGADGKPVALALHQGHYELDIQMKAAAEVIKANHALPY 111
Query: 70 EFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAY-NFDGIVMIASCDKIIPGMLM 128
CDG G GM SLP R + + ++R+ + ++ +ASCDK +P +M
Sbjct: 112 AVYVSDPCDGRTQGTTGMFDSLPYRNDASMVMRRLIRSLPDAKAVIGVASCDKGLPATMM 171
Query: 129 AMA-RLDIPAIFISGGPMLPGRFKGEYVDVKTVFEAVGAVKA-GKMSEKELKLLEDFACP 186
A+A + +I + + GG LP + + V+T+ GA A G++S ++ + AC
Sbjct: 172 ALAAQHNIATVLVPGGATLPAKDGEDNGKVQTI----GARFANGELSLQDARRAGCKACA 227
Query: 187 GCGS-CAGMFTANTMNALTEALGISLPWNGTAPAVYAHRIRIAKQTGMQIMKLVEEDLKP 245
G C + TA T + E LG+++P + AP+ IA+ + + L ++ +
Sbjct: 228 SSGGGCQFLGTAGTSQVVAEGLGLAIPHSALAPSGEPVWREIARASARAALNLSQKGITT 287
Query: 246 SDILTPEAFEDAIAVDMALGGSTNTVLHLMAIAREAGVKL-TLDTFDEISEKTPTLVKIS 304
+ILT +A E+A+ V A GGSTN +LH+ AIA +AG + T+D + I+++ P LV +
Sbjct: 288 REILTDKAIENAMTVHAAFGGSTNLLLHIPAIAHQAGCHIPTVDDWIRINKRVPRLVSVL 347
Query: 305 PAGK--HFVLDLYEAGGVLAIMKRLSELGLIHEDRITVSLKTVGE--------------- 347
P G H ++ + AGGV +M L LGL+HED +TV+ T+ E
Sbjct: 348 PNGPVYHPTVNAFMAGGVPEVMLHLRSLGLLHEDVMTVTGSTLKENLDWWEHSERRQRFK 407
Query: 348 -LLRDVSVLRDDVIRPVTRPYLSRG---GLMILYGSLAPKGAVLKVSAI-------PDIE 396
LL D + D + + +RG + G++AP+G+V+K +AI I
Sbjct: 408 QLLLDQEQINADEVIMSPQQAKARGLTSTITFPVGNIAPEGSVIKSTAIDPSMIDEQGIY 467
Query: 397 TFEGEARVFDCEEDAVKAILSGDIEKGDVVVIRYEGPKGGPGMREMLAPTSAIAGMGLDR 456
+G A+V+ E+ A+ I I+ GD++VI GP G GM E TSA+ + +
Sbjct: 468 YHKGVAKVYLSEKSAIYDIKHDKIKAGDILVIIGVGP-SGTGMEETYQVTSALKHLSYGK 526
Query: 457 DVALVTDGRFSGATRGLSIGHVSPEAAEGGPIALVEDGDLIRIDVKAKRI 506
V+L+TD RFSG + G IGHV PEA PI + GDLI I + + +
Sbjct: 527 HVSLITDARFSGVSTGACIGHVGPEALAEAPIGKLRTGDLIEIKIDCREL 576
>sp|Q9ZKB3|EDD_HELPJ PHOSPHOGLUCONATE DEHYDRATASE (6-PHOSPHOGLUCONATE DEHYDRATASE)
>gi|7436853|pir||E71859 phosphogluconate dehydratase -
Helicobacter pylori (strain J99)
>gi|4155606|gb|AAD06597.1| (AE001530) PHOSPHOGLUCONATE
DEHYDRATASE [Helicobacter pylori J99]
Length = 608
Score = 204 bits (513), Expect = 3e-51
Identities = 158/515 (30%), Positives = 258/515 (49%), Gaps = 54/515 (10%)
Query: 36 IVNSFNELIPGHIHLRRIAEAVKTGVRMSGGTPLEFSTI-GICDGIAMGHGGMKYSLPSR 94
I+ ++N+++ H + + +K ++ S + +CDGI G+ GM+ SL SR
Sbjct: 70 IITAYNDMLSAHQPFKNYPDLIKKELQEHNAYASVASGVPAMCDGITQGYEGMELSLFSR 129
Query: 95 ELIADSIEAVVRAYNFDGIVMIASCDKIIPGMLM-AMARLDIPAIFISGGPMLPGRFKGE 153
++IA S + FDG + CDKI+PG+L+ A++ ++ ++F+ GPM+ G +
Sbjct: 130 DVIALSTAVGLSHNVFDGAFFLGVCDKIVPGLLIGALSFGNLASVFVPSGPMVSGIENYK 189
Query: 154 YVDVKTVFEAVGAVKAGKMSEKELKLLEDFACPGCGSCAGMFTANTMNALTEALGISL-- 211
+ F GK++ +EL +E + G+C TAN+ + E +G+ +
Sbjct: 190 KAKARQDFAM------GKINREELLKVEMQSYHDVGTCTFYGTANSNQMMMEFMGLHVAN 243
Query: 212 -----PWNGTAPAVYAHRI-RIAKQTGMQIMKLVEEDLKPSDILTPEAFEDAIAVDMALG 265
P N + R+A + + KL++E ++ +A+ MA G
Sbjct: 244 SSFINPNNPLRKVLVEESAKRLASGKVLPLAKLIDE----------KSILNALIGLMATG 293
Query: 266 GSTNTVLHLMAIAREAGVKLTLDTFDEISEKTPTLVKISPAGKHFVLDLYEAGGVLAIMK 325
GSTN LHL+AIAR GV L D FD IS P L K+ P G V GG+ ++K
Sbjct: 294 GSTNHTLHLIAIARSCGVILNWDDFDAISNLIPLLAKVYPNGSADVNAFEACGGLAFVIK 353
Query: 326 RLSELGLIHEDRITV----------SLKTVGELLRDVSVLRD--------DVIRPVTRPY 367
L + GL+ ED T+ + L D V +D D++RPV+ P+
Sbjct: 354 ELLKEGLLFEDTHTIMDTETQKGMQNYTKTPFLENDQLVYKDAVSHSLNTDILRPVSEPF 413
Query: 368 LSRGGLMILYGSLAPKGAVLKVSAIPD-IETFEGEARVFDCEEDAVKAILSGDIEKGDVV 426
+ GGL IL G+L AV+K+SAI D + A VF + + ++ + ++E+ V
Sbjct: 414 AANGGLKILKGNLG--RAVIKISAIKDEHRKVKARAIVFKTQSEFLERFKNKELERDFVA 471
Query: 427 VIRYEGPK--GGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGL-SIGHVSPEAA 483
V+ ++GPK G P + ++ A+ MG VALVTDGR SGA+ + S H+SPE A
Sbjct: 472 VLPFQGPKSNGMPELHKLTTNLGALQDMGY--KVALVTDGRMSGASGKVPSAIHLSPEGA 529
Query: 484 EGGPIALVEDGDLIRIDVKAKRIDLLVDEEELKER 518
G I ++DGDLI +D +++L E++ ++R
Sbjct: 530 LNGAIIKIKDGDLIELDAPNNALNVL--EKDFEKR 562
>sp|P56111|EDD_HELPY PHOSPHOGLUCONATE DEHYDRATASE (6-PHOSPHOGLUCONATE DEHYDRATASE)
>gi|7436854|pir||D64657 phosphogluconate dehydratase (EC
4.2.1.12) - Helicobacter pylori (strain 26695)
>gi|2314249|gb|AAD08143.1| (AE000616) 6-phosphogluconate
dehydratase [Helicobacter pylori 26695]
Length = 608
Score = 203 bits (510), Expect = 6e-51
Identities = 156/515 (30%), Positives = 259/515 (50%), Gaps = 54/515 (10%)
Query: 36 IVNSFNELIPGHIHLRRIAEAVKTGVRMSGGTPLEFSTI-GICDGIAMGHGGMKYSLPSR 94
I+ ++N+++ H + + +K ++ S + +CDGI G+ GM+ SL SR
Sbjct: 70 IITAYNDMLSAHQPFKNYPDLIKKELQEHNAYASVASGVPAMCDGITQGYDGMELSLFSR 129
Query: 95 ELIADSIEAVVRAYNFDGIVMIASCDKIIPGMLM-AMARLDIPAIFISGGPMLPGRFKGE 153
++IA S + FDG + CDKI+PG+L+ A++ ++ ++F+ GPM+ G +
Sbjct: 130 DVIALSTAVGLSHNVFDGAFFLGVCDKIVPGLLIGALSFGNLASVFVPSGPMVSGIENYK 189
Query: 154 YVDVKTVFEAVGAVKAGKMSEKELKLLEDFACPGCGSCAGMFTANTMNALTEALGISL-- 211
+ F GK++ +EL +E + G+C TAN+ + E +G+ +
Sbjct: 190 KAKARQDFAM------GKINREELLKVEMQSYHDVGTCTFYGTANSNQMMMEFMGLHVAN 243
Query: 212 -----PWNGTAPAVYAHRI-RIAKQTGMQIMKLVEEDLKPSDILTPEAFEDAIAVDMALG 265
P N + R+A + + KL++E ++ +A+ MA G
Sbjct: 244 SSFINPNNPLRKVLVEESAKRLASGKVLPLAKLIDE----------KSILNALIGLMATG 293
Query: 266 GSTNTVLHLMAIAREAGVKLTLDTFDEISEKTPTLVKISPAGKHFVLDLYEAGGVLAIMK 325
GSTN LHL+AIAR GV L D FD +S P L K+ P G V GG++ ++K
Sbjct: 294 GSTNHTLHLIAIARSCGVILNWDDFDAVSNLIPLLAKVYPNGSADVNAFEACGGLVFVIK 353
Query: 326 RLSELGLIHEDRITVS----------------LKTVGELLRDV--SVLRDDVIRPVTRPY 367
L + GL+ ED T+ L+ + +D L D++RPV+ P+
Sbjct: 354 ELLKEGLLFEDTHTIMDTETQKGMQNYTKTPFLENNQLVYKDAINHSLNTDILRPVSDPF 413
Query: 368 LSRGGLMILYGSLAPKGAVLKVSAIPD-IETFEGEARVFDCEEDAVKAILSGDIEKGDVV 426
+ GGL IL G+L AV+K+SAI D + A VF + + ++ + ++E+ V
Sbjct: 414 AANGGLKILKGNLG--RAVIKISAIKDEHRKVKARAIVFKTQSEFLERFKNKELERDFVA 471
Query: 427 VIRYEGPK--GGPGMREMLAPTSAIAGMGLDRDVALVTDGRFSGATRGL-SIGHVSPEAA 483
V+ ++GPK G P + ++ A+ MG VALVTDGR SGA+ + S H+SPE A
Sbjct: 472 VLPFQGPKSNGMPELHKLTTNLGALQDMGY--KVALVTDGRMSGASGKVPSAIHLSPEGA 529
Query: 484 EGGPIALVEDGDLIRIDVKAKRIDLLVDEEELKER 518
G I ++DGDLI +D +++L E++ ++R
Sbjct: 530 LNGAIIKIKDGDLIELDAPNNALNVL--EKDFEKR 562
>emb|CAA70985.1| (Y09856) dihydroxy-acid dehydratase [Methanothermus fervidus]
Length = 144
Score = 193 bits (486), Expect = 4e-48
Identities = 88/136 (64%), Positives = 112/136 (81%)
Query: 1 MRSDVIKKGIERAPHRALFKAMGLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTG 60
M SD IKKG+ER+PHRAL +A G+TD + DKP IGI NSF E++PGHIHL+++++ VK G
Sbjct: 1 MISDEIKKGVERSPHRALLRACGVTDSDFDKPFIGIANSFTEIVPGHIHLKKLSKFVKLG 60
Query: 61 VRMSGGTPLEFSTIGICDGIAMGHGGMKYSLPSRELIADSIEAVVRAYNFDGIVMIASCD 120
+ +GG P EF+TI ICDGIAM H GMKYSL SRELIADSIE++ +A+ FDG+V+++SCD
Sbjct: 61 ISQAGGVPFEFNTIAICDGIAMNHEGMKYSLASRELIADSIESMAKAHCFDGLVLLSSCD 120
Query: 121 KIIPGMLMAMARLDIP 136
KIIPGMLMA AR+ P
Sbjct: 121 KIIPGMLMAAARIKHP 136
>gb|AAA23863.1| (L20897) 6-phosphogluconate dehydratase [Escherichia coli]
Length = 366
Score = 157 bits (393), Expect = 3e-37
Identities = 104/284 (36%), Positives = 163/284 (56%), Gaps = 26/284 (9%)
Query: 256 DAIAVDMALGGSTNTVLHLMAIAREAGVKLTLDTFDEISEKTPTLVKISPAGKHFVLDLY 315
+ I +A GGSTN +HL+A+AR AG+++ D F ++S+ P + ++ P G +
Sbjct: 52 NGIVALLATGGSTNHTMHLVAMARAAGIQINWDDFSDLSDVVPLMARLYPNGPADINHFQ 111
Query: 316 EAGGVLAIMKRLSELGLIHEDRITV-----SLKTVGELLRDVSV---------LRDDVIR 361
AGGV +++ L + GL+HED TV S T+ L + + L +VI
Sbjct: 112 AAGGVPVLVRELLKAGLLHEDVNTVAGFGLSRYTLEPWLNNGELDWREGAEKSLDSNVIA 171
Query: 362 PVTRPYLSRGGLMILYGSLAPKGAVLKVSAIP-DIETFEGEARVFDCEEDAVKAILSGDI 420
+P+ GG +L G+L AV+K SA+P + + E A VF+ + D + A +G +
Sbjct: 172 SFEQPFSHHGGTKVLSGNLG--RAVMKTSAVPVENQVIEAPAVVFESQHDVMPAFEAGLL 229
Query: 421 EKGDVVVIRYEGPK--GGPGMREMLAPTSAIAGMGLDR--DVALVTDGRFSGATRGL-SI 475
++ VVV+R++GPK G P + +++ P G+ LDR +ALVTDGR SGA+ + S
Sbjct: 230 DRDCVVVVRHQGPKANGMPELHKLMPP----LGVLLDRCFKIALVTDGRLSGASGKVPSA 285
Query: 476 GHVSPEAAEGGPIALVEDGDLIRIDVKAKRIDLLVDEEELKERK 519
HV+PEA +GG +A V DGD+IR++ + + LLVDE EL R+
Sbjct: 286 IHVTPEAYDGGLLAKVRDGDIIRVNGQTGELTLLVDEAELAARE 329
>emb|CAA26263.1| (X02413) pot. unidentified reading frame [Escherichia coli]
Length = 89
Score = 96.7 bits (237), Expect = 6e-19
Identities = 42/75 (56%), Positives = 55/75 (73%)
Query: 23 GLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTGVRMSGGTPLEFSTIGICDGIAM 82
G+TD + KP+I +VNSF + +PGH+HLR + + V + +GG EF+TI + DGIAM
Sbjct: 15 GMTDADFGKPIIAVVNSFTQFVPGHVHLRDLGKLVAEQIEAAGGVAKEFNTIAVDDGIAM 74
Query: 83 GHGGMKYSLPSRELI 97
GHGGM YSLPSRELI
Sbjct: 75 GHGGMLYSLPSRELI 89
>sp|P55186|ILVD_CAUCR DIHYDROXY-ACID DEHYDRATASE (DAD) >gi|1072874|pir||B53372
dihydroxy-acid dehydratase (EC 4.2.1.9) - Caulobacter
crescentus (fragment) >gi|403076|gb|AAA80549.1|
(L24392) ilvD [Caulobacter crescentus]
Length = 84
Score = 72.2 bits (174), Expect = 1e-11
Identities = 32/80 (40%), Positives = 48/80 (60%)
Query: 2 RSDVIKKGIERAPHRALFKAMGLTDEELDKPLIGIVNSFNELIPGHIHLRRIAEAVKTGV 61
RS G A R L++A G+ DE+ KP+I + NSF + +PGH+HL+ + + V +
Sbjct: 5 RSRTTTHGRNMAGARGLWRATGMKDEDFGKPIIAVANSFTQFVPGHVHLKDLGQLVAREI 64
Query: 62 RMSGGTPLEFSTIGICDGIA 81
+GG EF+TI + DGIA
Sbjct: 65 EAAGGVAKEFNTIAVDDGIA 84
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.319 0.139 0.394
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 202677995
Number of Sequences: 2977
Number of extensions: 8930822
Number of successful extensions: 24258
Number of sequences better than 1.0e-10: 66
Number of HSP's better than 0.0 without gapping: 56
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 23884
Number of HSP's gapped (non-prelim): 87
length of query: 551
length of database: 189,106,746
effective HSP length: 58
effective length of query: 493
effective length of database: 154,394,500
effective search space: 76116488500
effective search space used: 76116488500
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 167 (69.5 bits)