BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB0907 (acaB) DE:3-ketoacyl-CoA thiolase (acaB) (388 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||F75047 3-ketoacyl-coa thiolase (acab) PAB0907 - Pyrococcus ... 771 0.0 pir||E71113 probable nonspecific lipid-transfer protein - Pyroco... 741 0.0 pir||T45081 3-ketoacyl-CoA thiolase (acaB-12) homolog [imported]... 725 0.0 pir||G69205 lipid-transfer protein (sterol or nonspecific) - Met... 349 3e-95 gi|11499992 3-ketoacyl-CoA thiolase (acaB-12) [Archaeoglobus ful... 344 1e-93 pir||D64493 nonspecific lipid-transfer protein homolog - Methano... 328 5e-89 emb|CAC12576.1| (AL445067) probable 3-ketoacyl-CoA thiolase [The... 296 4e-79 gi|11497899 3-ketoacyl-CoA thiolase (acaB-7) [Archaeoglobus fulg... 276 3e-73 gi|11498050 3-ketoacyl-CoA thiolase (acaB-8) [Archaeoglobus fulg... 268 1e-70 gb|AAK42745.1| Acetyl-CoA c-acetyltransferase (acetoacetyl-CoA t... 265 7e-70 pir||A72689 probable nonspecific lipid-transfer protein APE0929 ... 263 2e-69 gb|AAK42980.1| Acetyl-CoA c-acetyltransferase (acetoacetyl-CoA t... 263 3e-69 gb|AAG19170.1| (AE005014) 3-ketoacyl-CoA thiolase; AcaB1 [Haloba... 256 2e-67 gb|AAG19361.1| (AE005031) 3-ketoacyl-CoA thiolase; AcaB2 [Haloba... 256 2e-67 emb|CAC11179.1| (AL445063) probable acetyl CoA synthase [Thermop... 252 4e-66 gi|11498889 3-ketoacyl-CoA thiolase (acaB-11) [Archaeoglobus ful... 247 2e-64 gi|11497655 3-ketoacyl-CoA thiolase (acaB-2) [Archaeoglobus fulg... 244 1e-63 gb|AAK42810.1| Acetyl-CoA c-acetyltransferase (acetoacetyl-CoA t... 234 1e-60 gi|11497639 3-ketoacyl-CoA thiolase (acaB-1) [Archaeoglobus fulg... 222 4e-57 pir||H72573 probable acetyl CoA synthase APE1872 - Aeropyrum per... 206 3e-52 gb|AAF89837.1|AF173961_3 (AF173961) putative benzoylsuccinyl-CoA... 190 2e-47 emb|CAC11495.1| (AL445064) sterol carrier protein x/sterol carri... 190 3e-47 gi|11497818 3-ketoacyl-CoA thiolase (acaB-6) [Archaeoglobus fulg... 189 4e-47 emb|CAB55378.1| (AL117263) possible 3-ketoacyl-CoA thiolase [Lei... 185 9e-46 gb|AAK42246.1| Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA t... 172 5e-42 pir||A39368 sterol carrier protein 2 precursor - rat >gi|202553|... 169 3e-41 pir||E70884 probable lipid-transfer protein - Mycobacterium tube... 168 1e-40 emb|CAA43061.1| (X60654) open reading frame for 58 kDa protein ... 168 1e-40 gb|AAB27044.1| 3-oxoacyl-CoA thiolase homolog {N-terminal} [rats... 168 1e-40 sp|P11915|NLTP_RAT NONSPECIFIC LIPID-TRANSFER PROTEIN PRECURSOR ... 167 2e-40 pir||A70559 hypothetical protein Rv1627c - Mycobacterium tubercu... 167 2e-40 gb|AAA42122.1| (M57453) sterol carrier protein-x [Rattus norvegi... 167 2e-40 sp|P32020|NLTP_MOUSE NONSPECIFIC LIPID-TRANSFER PROTEIN PRECURSO... 165 9e-40 gi|11498572 3-ketoacyl-CoA thiolase (acaB-9) [Archaeoglobus fulg... 163 3e-39 sp|P22307|NLTP_HUMAN NONSPECIFIC LIPID-TRANSFER PROTEIN PRECURSO... 162 6e-39 gb|AAB41286.1| (U11313) sterol carrier protein-X/sterol carrier ... 159 4e-38 gb|AAC15422.1| (AF051897) sterol carrier protein X [Oryctolagus ... 159 7e-38 pir||A34635 nonspecific lipid transfer protein precursor - rat ... 159 7e-38 gb|AAF53713.1| (AE003660) ScpX gene product [Drosophila melanoga... 157 2e-37 sp|Q07598|NLTP_CHICK NONSPECIFIC LIPID-TRANSFER PROTEIN PRECURSO... 156 3e-37 pir||B40407 sterol carrier protein 2-related form, 58.85K - human 153 3e-36 gb|AAF53712.1| (AE003660) CG17597 gene product [Drosophila melan... 152 9e-36 gb|AAK40853.1| Acetyl-CoA c-acetyltransferase (acetoacetyl-CoA t... 150 2e-35 emb|CAB57766.1| (Y18930) acetyl CoA synthase [Sulfolobus solfata... 150 2e-35 pir||G72467 probable non specific lipid-transfer protein APE2384... 148 1e-34 gi|11497751 3-ketoacyl-CoA thiolase (acaB-4) [Archaeoglobus fulg... 145 1e-33 pir||T27202 hypothetical protein Y57A10C.6 - Caenorhabditis eleg... 144 1e-33 emb|CAA66277.1| (X97685) sterol carrier protein x [Drosophila me... 141 1e-32 gi|11497750 3-ketoacyl-CoA thiolase (acaB-3) [Archaeoglobus fulg... 140 2e-32 emb|CAA64718.1| (X95443) sterol carrier protein x-related thiola... 138 1e-31 pir||E70676 probable nonspecific lipid-transfer protein Rv3540c ... 135 1e-30 pir||A83518 hypothetical protein PA1016 [imported] - Pseudomonas... 132 6e-30 pir||D70674 probable lipid carrier protein - Mycobacterium tuber... 125 8e-28 gb|AAB48108.1| (U41818) PhlC [Pseudomonas fluorescens] 125 8e-28 pir||B70582 probable lipid-transfer protein - Mycobacterium tube... 123 3e-27 gi|11498573 3-ketoacyl-CoA thiolase (acaB-10) [Archaeoglobus ful... 123 4e-27 pir||T50937 DitF protein [imported] - Pseudomonas abietaniphila ... 113 3e-24 gb|AAK42245.1| Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA t... 107 3e-22 gb|AAK43216.1| Acetyl-CoA c-acetyltransferase (acetoacetyl-CoA t... 106 3e-22 gb|AAK42641.1| Acetyl-CoA c-acetyltransferase (acetoacetyl-CoA t... 106 5e-22 gi|4506823 sterol carrier protein 2 [Homo sapiens] >gi|432977|gb... 97 3e-19 gb|AAA42120.1| (M34728) sterol carrier protein-2 (SCP-2) [Rattus... 94 2e-18 gi|11497817 3-ketoacyl-CoA thiolase (acaB-5) [Archaeoglobus fulg... 93 4e-18 emb|CAC00412.1| (AL160371) possible thiolase [Leishmania major] 89 7e-17 pir||E72467 probable non specific lipid-transfer protein APE2382... 82 1e-14 dbj|BAB11319.1| (AB016886) acetoacyl-CoA-thiolase [Arabidopsis t... 78 1e-13 pir||D70808 probable regulatory protein - Mycobacterium tubercul... 72 1e-11 gb|AAG17184.1|AF191029_2 (AF191029) FadA [Enterobacter cloacae] 71 2e-11 >pir||F75047 3-ketoacyl-coa thiolase (acab) PAB0907 - Pyrococcus abyssi (strain Orsay) >gi|5458788|emb|CAB50275.1| (AJ248287) 3-ketoacyl-CoA thiolase (acaB) [Pyrococcus abyssi] Length = 388 Score = 771 bits (1969), Expect = 0.0 Identities = 388/388 (100%), Positives = 388/388 (100%) Query: 1 MEKPIIVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVDSLYVGNMASGSFVEQEN 60 MEKPIIVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVDSLYVGNMASGSFVEQEN Sbjct: 1 MEKPIIVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVDSLYVGNMASGSFVEQEN 60 Query: 61 LGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSD 120 LGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSD Sbjct: 61 LGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSD 120 Query: 121 ATRYLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYA 180 ATRYLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYA Sbjct: 121 ATRYLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYA 180 Query: 181 MFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGM 240 MFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGM Sbjct: 181 MFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGM 240 Query: 241 GRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALG 300 GRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALG Sbjct: 241 GRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALG 300 Query: 301 VAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGI 360 VAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGI Sbjct: 301 VAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGI 360 Query: 361 QVPDAEIGLTQNIGGTGSNITVTILRRV 388 QVPDAEIGLTQNIGGTGSNITVTILRRV Sbjct: 361 QVPDAEIGLTQNIGGTGSNITVTILRRV 388 >pir||E71113 probable nonspecific lipid-transfer protein - Pyrococcus horikoshii >gi|3257084|dbj|BAA29767.1| (AP000003) 389aa long hypothetical nonspecific lipid-transfer protein (acethyl CoA synthetase) [Pyrococcus horikoshii] Length = 389 Score = 741 bits (1891), Expect = 0.0 Identities = 366/386 (94%), Positives = 378/386 (97%) Query: 3 KPIIVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVDSLYVGNMASGSFVEQENLG 62 K IIVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVDSLYVGNMASGSF+EQENLG Sbjct: 4 KVIIVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVDSLYVGNMASGSFIEQENLG 63 Query: 63 ALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDAT 122 ALIADWAGLGNIPAVK+EAACASGGAAVQEG KAVLSGLEDVVLVVGVEKMTDAWPSDAT Sbjct: 64 ALIADWAGLGNIPAVKIEAACASGGAAVQEGVKAVLSGLEDVVLVVGVEKMTDAWPSDAT 123 Query: 123 RYLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYAMF 182 RYLAYASDAEWELFHGVSFVALNAL+MR+YMNTYGYTEEDLALFAVNAHANGAKNPYAMF Sbjct: 124 RYLAYASDAEWELFHGVSFVALNALVMRYYMNTYGYTEEDLALFAVNAHANGAKNPYAMF 183 Query: 183 KRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMGR 242 K+PITVETVMKSPYIADPLKLFDASPVCDGAAAVIIT PEKAKELG+PKDKWVE+AGMGR Sbjct: 184 KKPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITTPEKAKELGVPKDKWVEVAGMGR 243 Query: 243 AIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALGVA 302 AIDTINLANREDLLTLKAAKIAAEKAYKMA VEPKDIDFFEVHDAFT+MAALSLEALGVA Sbjct: 244 AIDTINLANREDLLTLKAAKIAAEKAYKMAHVEPKDIDFFEVHDAFTIMAALSLEALGVA 303 Query: 303 EKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGIQV 362 EKG+GA LAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQ VE+ LQ+RGEAPNGIQV Sbjct: 304 EKGKGAMLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQAVEATLQLRGEAPNGIQV 363 Query: 363 PDAEIGLTQNIGGTGSNITVTILRRV 388 PDAE+GLTQNIGGTGSNITVTI RRV Sbjct: 364 PDAEVGLTQNIGGTGSNITVTIFRRV 389 >pir||T45081 3-ketoacyl-CoA thiolase (acaB-12) homolog [imported] - Pyrococcus furiosus >gi|1197356|emb|CAA59498.1| (X85250) acetyl CoA synthase [Pyrococcus furiosus] Length = 388 Score = 725 bits (1851), Expect = 0.0 Identities = 360/388 (92%), Positives = 375/388 (95%) Query: 1 MEKPIIVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVDSLYVGNMASGSFVEQEN 60 M K IIVGVGMTPVGEHWR+SLRDLAVEAIL AMDDAGIDKVDSLYVGNMASGSFVEQEN Sbjct: 1 MRKAIIVGVGMTPVGEHWRSSLRDLAVEAILNAMDDAGIDKVDSLYVGNMASGSFVEQEN 60 Query: 61 LGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSD 120 LGALIADWAGLGNIPAVK+EAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSD Sbjct: 61 LGALIADWAGLGNIPAVKIEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSD 120 Query: 121 ATRYLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYA 180 ATRYL YA+DAEWELFHG SFVALNALIMR YMNTYGY EEDLALFAVNAHANGAKNPYA Sbjct: 121 ATRYLGYAADAEWELFHGASFVALNALIMRLYMNTYGYKEEDLALFAVNAHANGAKNPYA 180 Query: 181 MFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGM 240 MFK+PITVETVMKSPYIADPLKLFDASPVCDGAAAVIIT PEKAKELGIPKDKW+EIAGM Sbjct: 181 MFKKPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITTPEKAKELGIPKDKWIEIAGM 240 Query: 241 GRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALG 300 GRAIDTINLANRED LTLKAA IAAE+AYKMA V+P+D+DFFEVHDAFTVMAALSLEALG Sbjct: 241 GRAIDTINLANREDFLTLKAATIAAERAYKMAGVKPEDVDFFEVHDAFTVMAALSLEALG 300 Query: 301 VAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGI 360 VA+KGEGAKLA EGQIAIDGDYPIQTMGGLKARGHPVGATGVYQ VE+VLQ+RGEAP+GI Sbjct: 301 VAKKGEGAKLAIEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQVVEAVLQLRGEAPDGI 360 Query: 361 QVPDAEIGLTQNIGGTGSNITVTILRRV 388 QVPDAE+GLTQNIGGTGSNITVT+LRRV Sbjct: 361 QVPDAEVGLTQNIGGTGSNITVTVLRRV 388 >pir||G69205 lipid-transfer protein (sterol or nonspecific) - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2621882|gb|AAB85293.1| (AE000857) lipid-transfer protein (sterol or nonspecific) [Methanobacterium thermoautotrophicum] Length = 383 Score = 349 bits (886), Expect = 3e-95 Identities = 189/389 (48%), Positives = 247/389 (62%), Gaps = 8/389 (2%) Query: 1 MEKPIIVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGID--KVDSLYVGNMASGSFVEQ 58 M ++GV T GE W S RD+ EA L A++DAG++ +D++YVGNM++G F++Q Sbjct: 1 MRDVAVIGVSQTKFGELWDVSFRDMITEAGLGAIEDAGVEGADLDAMYVGNMSAGLFIKQ 60 Query: 59 ENLGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWP 118 E++ +LIAD AGL IP+ +VEAACASGG A++ G AV SG D+V+ GVEKMTD Sbjct: 61 EHISSLIADHAGLTPIPSTRVEAACASGGLALRSGIMAVASGYHDIVIAAGVEKMTDV-- 118 Query: 119 SDATRYLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNP 178 D T +A ASD EWE GV+F +L A++ R +M YG T E LA+ +V H N + NP Sbjct: 119 VDPTPAIATASDQEWEAQQGVTFPSLYAMMARRHMYEYGTTREQLAMVSVINHENASNNP 178 Query: 179 YAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIA 238 A F +TVE VM S +ADPL+L D SP+ DGAAAVI+ + A+E D V + Sbjct: 179 RAQFPMKVTVEQVMNSTMVADPLRLLDCSPISDGAAAVILCPADMAREY---TDTPVYVK 235 Query: 239 GMGRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEA 298 +A TI L +R D+ + A AA A+KMAK+ P DID EVHD F++ L++E Sbjct: 236 ASAQASGTIALHDRRDITRIDATVNAARNAFKMAKLTPGDIDLVEVHDCFSINGILAVED 295 Query: 299 LGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPN 358 LG EKGEG + ++G IDGD P+ GGLKARGHP+GATG+ Q E V Q+RGEA Sbjct: 296 LGFVEKGEGGRAFEDGMTRIDGDIPVNPSGGLKARGHPLGATGIAQAAEVVWQLRGEAGK 355 Query: 359 GIQVPDAEIGLTQNIGGTGSNITVTILRR 387 QV AEIG+T NIGGTG V I R Sbjct: 356 R-QVEGAEIGMTHNIGGTGGTAAVHIFSR 383 >gi|11499992 3-ketoacyl-CoA thiolase (acaB-12) [Archaeoglobus fulgidus] >gi|7450462|pir||A69552 3-ketoacyl-CoA thiolase (acaB-12) homolog - Archaeoglobus fulgidus >gi|2650673|gb|AAB91246.1| (AE001108) 3-ketoacyl-CoA thiolase (acaB-12) [Archaeoglobus fulgidus] Length = 384 Score = 344 bits (873), Expect = 1e-93 Identities = 191/391 (48%), Positives = 260/391 (65%), Gaps = 11/391 (2%) Query: 1 MEKPIIVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGID--KVDSLYVGNMASGSFVEQ 58 M + +VGVG + GE W RD+ +EA +A++DA ++ ++++++VGNM+ G ++ Q Sbjct: 1 MRRVAVVGVGQSKFGELWEKGFRDIVLEAGREALEDADLEGREIEAMFVGNMSGGRYLGQ 60 Query: 59 ENLGALIADWAGLGN--IPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDA 116 E++ ALIAD+AGL IPA +VEAA ASGG AV++ AV SGL D+V+ G EK+TD Sbjct: 61 EHVAALIADYAGLAEFGIPATRVEAADASGGLAVRQAYMAVASGLHDIVIAAGAEKVTDV 120 Query: 117 WPSDATRYLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAK 176 D + L+ + D EWE F G S AL A+I R +M+++G TEEDLAL +V H NGAK Sbjct: 121 --DDPMQILSSSVDVEWENFVGGSLPALYAIIARLHMDSFGTTEEDLALVSVKNHRNGAK 178 Query: 177 NPYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVE 236 NP A F++ I VE V+ SPY+A+PLKL D + V DGAAAVI+ + A+E+ D V Sbjct: 179 NPKAQFRKEIRVEDVLNSPYVAEPLKLLDCASVSDGAAAVILASEDVAREI---TDTPVF 235 Query: 237 IAGMGRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSL 296 I +A D + L +R+D+L+++A A+ AY++A V PKDI EVHD+FT+ L+ Sbjct: 236 IEACTQASDYLALQSRKDILSMRAVVKASRDAYELAGVGPKDIQVAEVHDSFTIAEILAY 295 Query: 297 EALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEA 356 E LG AEKG+GA+L +EG I G P+ GGLKA GH VGATGV Q VE LQ+RGEA Sbjct: 296 EDLGFAEKGKGAELVREGVTEIGGKIPVNPSGGLKACGHAVGATGVRQIVELTLQLRGEA 355 Query: 357 PNGIQVPDAEIGLTQNIGGTGSNITVTILRR 387 G + DAE GL NIGGTG+ V+ILRR Sbjct: 356 --GERQVDAETGLALNIGGTGATAVVSILRR 384 >pir||D64493 nonspecific lipid-transfer protein homolog - Methanococcus jannaschii >gi|1592180|gb|AAB99567.1| (U67595) 3-keto-acyl-CoA thiolase [Methanococcus jannaschii] Length = 392 Score = 328 bits (833), Expect = 5e-89 Identities = 184/395 (46%), Positives = 253/395 (63%), Gaps = 17/395 (4%) Query: 1 MEKPIIVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGID--KVDSLYVGNMASGSFVEQ 58 M I+G G T GE W S R L VEA +KA++ AGID +D +YVGNM++G FV Q Sbjct: 1 MRDVAIIGYGQTKFGELWERSFRSLIVEAGVKAVEAAGIDGKDIDEMYVGNMSAGLFVGQ 60 Query: 59 ENLGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWP 118 E++ +LIA+ AGL IP+ +VEAACASG A+++ V SG DVVLV GVEKMTD Sbjct: 61 EHIASLIAEHAGLNPIPSTRVEAACASGSLALRQAVLNVASGASDVVLVGGVEKMTDV-- 118 Query: 119 SDATRYLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNP 178 DAT ++ ASD EWE G +F +L A++ + YM YG T E+L++++V H N +KN Sbjct: 119 VDATSAISSASDQEWEALFGATFPSLYAMMAQRYMYEYGLTLEELSMWSVIMHENASKNR 178 Query: 179 YAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIA 238 YA F +T+E V+ S +A+PL+L SPV DGAAA+I+ EKAKE + KD + I Sbjct: 179 YAQFPFKVTLEQVLNSSPVAEPLRLLHCSPVSDGAAALIVCEAEKAKEF-VNKDDIIYIK 237 Query: 239 GMGRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEA 298 +A DTI L +RE + +LKAAK+A+EKAYKMA +EPKD+D EVHD F + + +E Sbjct: 238 ASVQASDTIALHSRESITSLKAAKVASEKAYKMANIEPKDVDVAEVHDCFAINGLILMEE 297 Query: 299 LGVAEKGEGAKLAKEGQIAIDGD-YP-IQTMGGLKARGHPVGATGVYQTVESVLQIRGEA 356 LG +KGE K+ + +IAID D +P + GGLKA GH +GATG+ Q E Q++ + Sbjct: 298 LGFCKKGEAGKIVYDKKIAIDYDGFPAVNPSGGLKAAGHALGATGIRQVGEIYWQLKQDK 357 Query: 357 PNGIQVPDAEI------GLTQNIGGTGSNITVTIL 385 +V D ++ G+T N+GGTG + + IL Sbjct: 358 ----EVKDRQVEIKNGYGITVNVGGTGGTVCIHIL 388 >emb|CAC12576.1| (AL445067) probable 3-ketoacyl-CoA thiolase [Thermoplasma acidophilum] Length = 387 Score = 296 bits (749), Expect = 4e-79 Identities = 167/384 (43%), Positives = 243/384 (62%), Gaps = 10/384 (2%) Query: 6 IVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVD--SLYVGNMASGSFVEQENLGA 63 I+G G T GE W SLRDLAVEA L+A+ DA I D LY N +G+ EQ N+ A Sbjct: 8 IIGAGETKFGELWDKSLRDLAVEAGLEAIKDANIYSRDLQMLYASNSLAGTINEQSNIAA 67 Query: 64 LIADWAGLG--NIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDA 121 L AD++G+ ++PAV+VEA+ ASGGAAV+E A+ SG DVV+V GVEKMTD + S+ Sbjct: 68 LAADFSGIAETHVPAVRVEASTASGGAAVREAYLAIKSGEYDVVMVGGVEKMTDIYGSEI 127 Query: 122 TRYLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYAM 181 + D EWE F+G + AL A+ R YM+ + ED+A+ AVN HAN + NP A Sbjct: 128 IDVQSSILDREWESFNGATPAALAAITARRYMHDFKVPREDIAMIAVNDHANASMNPDAQ 187 Query: 182 FKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMG 241 ++ ITVE V+ S +A+PL +FD SP+ DGA+A+I+ E K+ + + I Sbjct: 188 YRNKITVEQVINSDPVAEPLNVFDCSPISDGASAIILASDEYRKKNRL---DGIRIVSSA 244 Query: 242 RAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALGV 301 + D + L +R+ + TL++A+IA+++A + A ++ DI F E++D++++ L LE LG Sbjct: 245 MSEDYLALHSRKSIYTLESARIASKQALERAGIKKNDISFLELNDSYSIYGLLELEDLGF 304 Query: 302 AEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGIQ 361 AEKG+G +L G+I I+G P+ GGLKA+G+P+GATGV Q E+ LQ++G+A Q Sbjct: 305 AEKGKGRELL--GEIKINGSLPVNPSGGLKAKGNPLGATGVSQFYEAYLQLKGKAGQR-Q 361 Query: 362 VPDAEIGLTQNIGGTGSNITVTIL 385 V A G+ N+ GTG+ V I+ Sbjct: 362 VKGARYGMLHNMAGTGATSVVHIV 385 >gi|11497899 3-ketoacyl-CoA thiolase (acaB-7) [Archaeoglobus fulgidus] >gi|7450468|pir||C69285 3-ketoacyl-CoA thiolase (acaB-7) homolog - Archaeoglobus fulgidus >gi|2650353|gb|AAB90950.1| (AE001085) 3-ketoacyl-CoA thiolase (acaB-7) [Archaeoglobus fulgidus] Length = 396 Score = 276 bits (699), Expect = 3e-73 Identities = 167/390 (42%), Positives = 227/390 (57%), Gaps = 10/390 (2%) Query: 2 EKPIIVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVDSLYVGNMASGSFVEQENL 61 E ++GVG + G ++ +L E++ A + A ++ D + +G + + + Sbjct: 4 ENVAVIGVGHSKFGTRKDVNIAELCWESMKPAFESANLEPKDIEFFVVSNAGMWSSEAAV 63 Query: 62 GALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDA 121 AL+A++A L +++VEAACASG AAV+ G AV SG+ D+VLV+GVEKM ++ + Sbjct: 64 PALMAEYADLAPKGSMRVEAACASGSAAVRVGYTAVKSGMADIVLVLGVEKMQESPNPNV 123 Query: 122 TRYLAYASDAEWELFH-GVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYA 180 + WE + G++F A AL YM YG TEED A AV H GAKNPYA Sbjct: 124 IELIGRFGSYFWEFENFGLTFPAYYALHGTAYMMKYGATEEDYAKVAVKNHYYGAKNPYA 183 Query: 181 MFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGM 240 F+R I VETVMKSPY+A P KLFD SP+ DG+A +I+ EK KELGI + W I G Sbjct: 184 QFQREIDVETVMKSPYVAWPFKLFDCSPITDGSACIILASEEKVKELGIDEKIW--ILGQ 241 Query: 241 GRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKD----IDFFEVHDAFTVMAALSL 296 G T NL+ RE+ +L +A AAE+AYKMA ++ D +D VHD FT ++ Sbjct: 242 GVGTGTANLSRREEFSSLASATYAAEQAYKMAGIDIDDPTKYLDGANVHDCFTAPEIIAY 301 Query: 297 EALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEA 356 E L ++GEG KL +E Q I G P+ GGLKA+GHP+GATGV Q VE+ Q+ +A Sbjct: 302 EDLRFCKRGEGYKLIREEQTYIGGKIPVNVDGGLKAKGHPIGATGVSQAVEAYKQLLQKA 361 Query: 357 PNGIQVPDAEIG--LTQNIGGTGSNITVTI 384 G Q D G L N+GGTG VTI Sbjct: 362 EPGRQA-DINKGRWLAHNVGGTGHYSYVTI 390 >gi|11498050 3-ketoacyl-CoA thiolase (acaB-8) [Archaeoglobus fulgidus] >gi|7450467|pir||F69304 3-ketoacyl-CoA thiolase (acaB-8) homolog - Archaeoglobus fulgidus >gi|2650194|gb|AAB90795.1| (AE001074) 3-ketoacyl-CoA thiolase (acaB-8) [Archaeoglobus fulgidus] Length = 387 Score = 268 bits (677), Expect = 1e-70 Identities = 157/388 (40%), Positives = 223/388 (57%), Gaps = 11/388 (2%) Query: 6 IVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGI--DKVDSLYVGNMASGSFVEQENLGA 63 ++GVG + G +++LA EA+ +A+DDAGI D+V+ VG++ + + E + A Sbjct: 5 VIGVGCSRFGRRDDAVIQELAYEAVKEALDDAGITQDEVELSVVGSVNTRGY---ELMPA 61 Query: 64 L-IADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDAT 122 + + ++ G ++VEAACA+G AAV ++ SG+ DV + +GVEKMT+ + + Sbjct: 62 VPVNEYCGFAGKGPLRVEAACATGAAAVYTAYTSIASGMADVAIAIGVEKMTEVDTATSL 121 Query: 123 RYLAYASDAEWELF-HGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYAM 181 A + WE +G +F A A+ +M YG TEE +A AV AH N A+NP A Sbjct: 122 AIGGRAGNYLWEFHQYGTTFPAYYAMHATAHMAKYGTTEEQMAKVAVKAHRNAARNPKAH 181 Query: 182 FKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMG 241 F++ I VE V+ S YI PLKL+D SP+ DG+AA I+ EK +ELGI W++ +G Sbjct: 182 FQKEIAVEDVLNSRYITYPLKLYDCSPISDGSAAAILASEEKIRELGIDDVVWID--SVG 239 Query: 242 RAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEP--KDIDFFEVHDAFTVMAALSLEAL 299 A DT N+ NRE + LKA +A E AY+ A +E K +DF VHD FT+ ++ E L Sbjct: 240 YASDTSNMTNRESFVGLKATVLAREMAYRKAGIEEPVKQLDFATVHDCFTIAEIMAYEDL 299 Query: 300 GVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNG 359 G KGEG KL + G+ + G P+ T GGLKA+GHP+ ATGV E V Q+RGEA Sbjct: 300 GFCRKGEGGKLVESGETELGGKLPVNTFGGLKAKGHPLAATGVAMVYEIVKQLRGEAGEL 359 Query: 360 IQVPDAEIGLTQNIGGTGSNITVTILRR 387 L N+GGTG V I R Sbjct: 360 QVELRNNRALLHNVGGTGHFAFVMIFGR 387 >gb|AAK42745.1| Acetyl-CoA c-acetyltransferase (acetoacetyl-CoA thiolase) (acaB-7) [Sulfolobus solfataricus] Length = 387 Score = 265 bits (670), Expect = 7e-70 Identities = 154/386 (39%), Positives = 221/386 (56%), Gaps = 9/386 (2%) Query: 6 IVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVDSLYVGNMASGSFVEQE---NLG 62 ++GVG + G S+++LA E+I +A++D+G+ + D +G + GS + Sbjct: 7 VIGVGNSKFGRRDDVSIQELAWESIKEALNDSGVSQSD---IGLVVIGSTAYRGIELYPA 63 Query: 63 ALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDAT 122 ++A+++GL ++VEA CA+G AA AV SGL D+ + VGV+KMT+ S + Sbjct: 64 PIVAEYSGLTGKVPLRVEAMCATGLAAALSAYTAVASGLVDIAMAVGVDKMTEVDTSTSL 123 Query: 123 RYLAYASDAEWEL-FHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYAM 181 + +WE F+G +F AL +M +G TEE +AL +V AH G+ NP A Sbjct: 124 AIGGRGGNYQWEYHFYGTTFPTYYALYATRHMAVFGTTEEQMALVSVKAHKYGSMNPKAH 183 Query: 182 FKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMG 241 F++P+TVE V+KS I+ P+KL D+ P+ DG+A + EK KEL I W I G+G Sbjct: 184 FQKPVTVEEVLKSRVISWPIKLLDSCPISDGSATAVFASEEKVKELKIDSPVW--ITGIG 241 Query: 242 RAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALGV 301 A D +A R + + KA ++AA +AY+MAKV P DI+ VHDAFT+ + E LG Sbjct: 242 YANDYAYVARRGEWVGFKATQLAARQAYEMAKVTPNDIEVATVHDAFTIAEIMGYEDLGF 301 Query: 302 AEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGIQ 361 EKG+G K +EGQ G + GGLKA+GHP+GATG+ E Q+R EA Q Sbjct: 302 TEKGKGGKFIEEGQSEKGGKVGVNLFGGLKAKGHPLGATGLSMIYEITKQLRDEADKLQQ 361 Query: 362 VPDAEIGLTQNIGGTGSNITVTILRR 387 IGL N+GGTG V ILRR Sbjct: 362 PLKKYIGLVHNVGGTGHFAYVMILRR 387 >pir||A72689 probable nonspecific lipid-transfer protein APE0929 - Aeropyrum pernix (strain K1) >gi|5104598|dbj|BAA79913.1| (AP000060) 400aa long hypothetical nonspecific lipid-transfer protein [Aeropyrum pernix] Length = 400 Score = 263 bits (666), Expect = 2e-69 Identities = 160/390 (41%), Positives = 229/390 (58%), Gaps = 19/390 (4%) Query: 6 IVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGID--KVDSLYVGNMASGSFVEQENLGA 63 IVG G + G ++ +LA EA+ +A +AGI+ VD + VGN +G + + Sbjct: 10 IVGTGHSKFGVRNDVNIAELAWEAMREAASEAGIELRDVDQVVVGN--AGGWSSEYLSSI 67 Query: 64 LIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDATR 123 ++ ++AG+ P +VEAACA+G AA++ A+ +G D+VLVVGVEKM ++ Sbjct: 68 VLLEYAGISGKPVYRVEAACATGSAAIKAAHDAIAAGEADLVLVVGVEKMNESPTPIVVE 127 Query: 124 YLAYASDAEWELFH-GVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYAMF 182 + A + WE + G++F AL YM+ +G TEEDL AV H + + NP A F Sbjct: 128 MIGRAGNYFWEFENFGLTFPGYYALYATAYMSEFGATEEDLCRVAVKNHHHASMNPKAHF 187 Query: 183 KRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMGR 242 R IT+E ++S Y+A PLKL+D+SP+ DGAAAV++ + A++L D V I +G Sbjct: 188 PRAITLEQCLQSRYVAWPLKLYDSSPITDGAAAVVMASEDLARKL---TDSPVWIHSIGM 244 Query: 243 AIDTINLANREDLLTLKAAKIAAEKAYKMAKVEP----KDIDFFEVHDAFTVMAALSLEA 298 A DT NL+ R D L +A+++AAE+A+K +E K DF VHDAFT+ L+ EA Sbjct: 245 ASDTSNLSKRPDFLVHRASRLAAERAFKKLGIEIEGSYKHFDFANVHDAFTIAEILAYEA 304 Query: 299 LGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPN 358 +G A+ GEG KL +E Q + G P+ GGLKA+GHP+GATGV VE V Q++G Sbjct: 305 MGFAKLGEGYKLVREEQTYVGGLIPVNLDGGLKAKGHPIGATGVSMAVEHVRQLQGRVEK 364 Query: 359 GIQVPDAEI----GLTQNIGGTGSNITVTI 384 G Q AEI L N+GGTG VT+ Sbjct: 365 GRQ---AEIKRGRSLAHNVGGTGHYAFVTV 391 >gb|AAK42980.1| Acetyl-CoA c-acetyltransferase (acetoacetyl-CoA thiolase) (acaB-9) [Sulfolobus solfataricus] Length = 395 Score = 263 bits (665), Expect = 3e-69 Identities = 158/392 (40%), Positives = 226/392 (57%), Gaps = 13/392 (3%) Query: 1 MEKPIIVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVDSLY--VGNMASGSFVEQ 58 M I+G G T G +L++LA EA+ +A+++A ID+ + Y VGN+ G++ + Sbjct: 1 MRNVAIIGTGHTKFGVRTDVNLQELAWEAVKQALEEANIDQNEIQYFVVGNV--GNWSSE 58 Query: 59 ENLGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWP 118 E ++ ++ L ++VEAAC++G AA+++ A+ SG D+ LVVGVE+M A Sbjct: 59 ELPAVIVGEYCNLTPKGTMRVEAACSTGSAAIRDAYLAIKSGEADIALVVGVEQMHQAPN 118 Query: 119 SDATRYLAYASDAEWELFH-GVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKN 177 + A WE + G++F AL YM YG EEDL A+ H GAKN Sbjct: 119 PQVVELIGRAGGYFWEFENFGLTFPGYYALHASAYMAKYGMKEEDLGKIAIKNHYYGAKN 178 Query: 178 PYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEI 237 PYA F++ IT+E +KS +A PLKL D+SP+ DGAAA+++ E AK++ D V I Sbjct: 179 PYAQFQKEITMEEYLKSKPVAYPLKLLDSSPITDGAAAIVLASEEVAKKI---TDSPVWI 235 Query: 238 AGMGRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVE----PKDIDFFEVHDAFTVMAA 293 G A T NL+ R D ++AA IAA++AYK A++E K+ D +VHD FT+ Sbjct: 236 VSQGVASGTANLSRRTDFTHIEAAHIAAQQAYKRARIEFDNAWKNFDVADVHDCFTIAEI 295 Query: 294 LSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIR 353 ++ E LG A++GEG LA+E Q I G P+ GGLKA+GHP+GATGV V Q+ Sbjct: 296 MAYEDLGFAKRGEGYLLAREEQTYIGGKIPVNVDGGLKAKGHPIGATGVSMAVSITRQLL 355 Query: 354 GEAPNGIQVPDAE-IGLTQNIGGTGSNITVTI 384 A G QV +G+T N+GGTG VTI Sbjct: 356 YRAHKGTQVEVRNGMGITHNVGGTGHYAYVTI 387 >gb|AAG19170.1| (AE005014) 3-ketoacyl-CoA thiolase; AcaB1 [Halobacterium sp. NRC-1] Length = 395 Score = 256 bits (648), Expect = 2e-67 Identities = 147/385 (38%), Positives = 218/385 (56%), Gaps = 5/385 (1%) Query: 6 IVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVD--SLYVGNMASGSFVEQENLGA 63 + GVG+T G H + RDL EA L A+DDAG+ + D +++ GN Q + G Sbjct: 6 VAGVGLTHFGVHPERTSRDLFAEAGLAALDDAGVAREDVAAVHYGNFMGELSEHQGHQGP 65 Query: 64 LIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDATR 123 L+A+ GL ++PA + E+ACAS G A++ + V +G DVV+V G E+M + +++T Sbjct: 66 LVAEALGL-DVPATRYESACASSGVALRRAVRDVRNGEADVVVVGGAERMNNLETAESTD 124 Query: 124 YLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYAMFK 183 LA A+D +E+ G++F AL+ Y +G + EDLA AV HAN N A ++ Sbjct: 125 ALAIAADGLYEVRAGMTFPGAYALMAASYFEQFGGSREDLAHIAVKNHANAVDNDRAQYQ 184 Query: 184 RPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMGRA 243 + ITV ++SP +A+PL L+DA PV DGA+A+++ A + V + G G+ Sbjct: 185 QAITVADALESPPVAEPLHLYDACPVTDGASALVLVSESYADTHDVSAP--VAVTGTGQG 242 Query: 244 IDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALGVAE 303 D + L +R+++ T AA AA +AY A V D+D EVHD FT+ ++ E+LG + Sbjct: 243 GDKMALQDRQNMATSPAATDAATEAYADAGVSADDVDVAEVHDCFTIAEVMATESLGFFD 302 Query: 304 KGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGIQVP 363 G G A+EG DG P+ GGLKA+GHPVGATG Q E +RG+ N V Sbjct: 303 PGAGITAAREGVTTKDGRLPVNLSGGLKAKGHPVGATGTSQVAELTRLLRGDHVNSEHVA 362 Query: 364 DAEIGLTQNIGGTGSNITVTILRRV 388 DA+ + N GGT ++ V +L V Sbjct: 363 DAQTAVAHNAGGTVASAVVHVLETV 387 >gb|AAG19361.1| (AE005031) 3-ketoacyl-CoA thiolase; AcaB2 [Halobacterium sp. NRC-1] Length = 383 Score = 256 bits (648), Expect = 2e-67 Identities = 159/392 (40%), Positives = 222/392 (56%), Gaps = 15/392 (3%) Query: 1 MEKPIIVGVGMTPVGEH--WRTSLRDLAVEAILKAMDDAGID--KVDSLYVGNMASGSFV 56 M++ I+G MT G+ W L L EA A+ DAG+D VD LYV NMASG F Sbjct: 1 MDRVAIIGASMTAFGDRDAW---LLALLAEAGDAALTDAGVDGDDVDHLYVSNMASGEFE 57 Query: 57 EQENL-GALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTD 115 Q + AL D A + A +++ +SGGA + ++V SG D+ L+VG EKMT Sbjct: 58 GQTGVPNALAHDLAAMPAYTA-RIDQTSSSGGAGIYAAWQSVASGASDLTLLVGGEKMTH 116 Query: 116 AWPSDATRYLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGA 175 +AT +A + E HGV+ + L R Y+ Y E L AV H NG Sbjct: 117 RTTGEATDVIASLTHPV-EYKHGVTLPSFAGLTARKYLAQYDAPRESLGKVAVKNHRNGL 175 Query: 176 KNPYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWV 235 NP+A F++ + +ETV+ SP +ADPL+L+D P+ DG+AA+++ A E D +V Sbjct: 176 DNPHAQFRKEVDLETVLDSPMVADPLRLYDFCPITDGSAALVLCPESVAAEY---TDDYV 232 Query: 236 EIAGMGRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALS 295 I+G+ A DT + R+D T++ +AE+AY+MA P DID E+HD FT++ L Sbjct: 233 VISGVAGATDTHVVHERDDPTTMRGVVESAEQAYEMAGRGPDDIDVAELHDMFTILEFLQ 292 Query: 296 LEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGE 355 E LG EKG G K ++G DGD PI T GGLK++GHP+GA+GV Q E Q+ G Sbjct: 293 SEDLGFFEKGAGWKAVRDGVTDRDGDLPINTSGGLKSKGHPLGASGVAQAYELYQQLLGT 352 Query: 356 APNGIQVPDAEIGLTQNIGGTGSNITVTILRR 387 A G + DAE+GL N+GG G+ +T TIL + Sbjct: 353 A--GDRQVDAEVGLACNVGGFGNCVTTTILEQ 382 >emb|CAC11179.1| (AL445063) probable acetyl CoA synthase [Thermoplasma acidophilum] Length = 391 Score = 252 bits (638), Expect = 4e-66 Identities = 155/394 (39%), Positives = 227/394 (57%), Gaps = 17/394 (4%) Query: 1 MEKPIIVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDK--VDSLYVGNMASGSFVEQ 58 M + I+G G++ G+ S+ DL EA +A+ +G+DK +D + V NM S Sbjct: 2 MNRVAIIGYGISKFGKRTDASMYDLIWEAGSEAIRSSGVDKKDIDYMVVSNMGMWS---S 58 Query: 59 ENLGALIA-DWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAW 117 E L A++A + G+ N +VEAACASG +A+ A+ SG + + +G+EKM + Sbjct: 59 EELPAVVAGEVLGIRNAGLHRVEAACASGSSAIASAYDAIRSGRSKIAIALGIEKMNEVE 118 Query: 118 PSDATRYLAYASDAEWEL-FHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAK 176 A + A + WE F G++F AL Y+N Y EEDLAL +V H Sbjct: 119 SETAIELIGRAGNFLWEYEFFGLTFPGYYALYATAYLNRYSGKEEDLALVSVKNHHYAHL 178 Query: 177 NPYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVE 236 NP A F ITV+ VMKS YIA PLKL+D+SP+ DG+AAVI+ + AK+ D V Sbjct: 179 NPIAHFSNEITVDDVMKSRYIASPLKLYDSSPITDGSAAVILASEDVAKQY---TDTPVW 235 Query: 237 IAGMGRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEP----KDIDFFEVHDAFTVMA 292 I +G + T NL+ R+D + ++AA+ AA KAY+MAK++ + +D +VHD F++ Sbjct: 236 IDAIGSNLGTANLSKRDDFVHIEAAREAAAKAYRMAKIDAAKPYRYLDGADVHDCFSIAE 295 Query: 293 ALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQI 352 L+ E LG AE+G+G + ++G+ I G P+ GGL ++GHP+GATGV VE+ Q+ Sbjct: 296 VLAYEDLGFAERGKGLDMLRDGETYIGGKIPVNVDGGLISKGHPIGATGVAMAVEASKQL 355 Query: 353 RGEAPNGIQVPDAEIG--LTQNIGGTGSNITVTI 384 +A G Q+ D + G LT N+GGTG VTI Sbjct: 356 LRKAEPGRQI-DVKNGKFLTHNVGGTGHYAYVTI 388 >gi|11498889 3-ketoacyl-CoA thiolase (acaB-11) [Archaeoglobus fulgidus] >gi|7450464|pir||B69411 3-ketoacyl-CoA thiolase (acaB-11) homolog - Archaeoglobus fulgidus >gi|2649290|gb|AAB89956.1| (AE001015) 3-ketoacyl-CoA thiolase (acaB-11) [Archaeoglobus fulgidus] Length = 392 Score = 247 bits (623), Expect = 2e-64 Identities = 157/394 (39%), Positives = 214/394 (53%), Gaps = 16/394 (4%) Query: 6 IVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVD--SLYVGNMASGSFVEQENLGA 63 ++GVGMT G+H SL DL EA +A +++ I+ D +LY GN NL Sbjct: 3 VLGVGMTKFGKHPDKSLVDLFAEAFYEAFEESNIELKDIQALYYGNFVGEMTDGSGNLSG 62 Query: 64 LIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDATR 123 +AD GL IPA++ E ACAS A +E +AV +G D+V V G E++ A TR Sbjct: 63 FMADEIGLRGIPAIRYEGACASSSVAFREAVRAVAAGYYDIVAVGGSERLYTAGTEIGTR 122 Query: 124 YLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDL----ALFAVNAHANGAKNPY 179 LA A D +E+ G++F + AL R Y Y E+L A+ +V H GA NP Sbjct: 123 ALATAVDGVYEITAGLTFPGVFALAARLYSKKYEIPLEELREMMAMVSVKNHRYGAINPK 182 Query: 180 AMFKRPI---TVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVE 236 A F + VE V+ S I+ PL L D P+ DG +A II + A+EL D V Sbjct: 183 AQFYGKLGDLKVEDVLNSRMISSPLTLLDCCPMTDGGSAAIIAAADLAEEL---VDTPVY 239 Query: 237 IAGMGRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSL 296 + G G++ +ED++ + A+E A+K A + PKDIDF EVHD FT+ ++L Sbjct: 240 VRGTGQSSAGGLFRQKEDIIRAIPRRKASEMAFKEANMTPKDIDFVEVHDCFTIAEIIAL 299 Query: 297 EALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEA 356 EA+G E G+G KEG +IDGD P+ GGL +GHPVGATGV Q V Q+RGE Sbjct: 300 EAMGFFEYGQGCYAVKEGVTSIDGDLPVNPDGGLIGKGHPVGATGVSQVYSVVKQLRGEF 359 Query: 357 PNGIQVPDAEIGLTQNIG---GTGSNITVTILRR 387 V DAE G+T +G GT NI +++ RR Sbjct: 360 KEN-PVKDAETGMTDTLGGDFGTLVNIILSVHRR 392 >gi|11497655 3-ketoacyl-CoA thiolase (acaB-2) [Archaeoglobus fulgidus] >gi|7450465|pir||B69254 3-ketoacyl-CoA thiolase (acaB-2) homolog - Archaeoglobus fulgidus >gi|2650617|gb|AAB91194.1| (AE001104) 3-ketoacyl-CoA thiolase (acaB-2) [Archaeoglobus fulgidus] Length = 417 Score = 244 bits (617), Expect = 1e-63 Identities = 153/392 (39%), Positives = 220/392 (56%), Gaps = 15/392 (3%) Query: 1 MEKPIIVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVDSLYVGNMASGSFVEQEN 60 M + ++G G+T G HW DL VEA +A+ DA ++ D V + G+F Sbjct: 35 MREVAVIGCGVTKFGHHWEKDHEDLLVEATYEAIADANVELKD---VEAVWCGTFYPSTG 91 Query: 61 L-GALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPS 119 + G + +D P +VE CA+G ++ A AV SG D+V+ GVEK+ DA Sbjct: 92 ISGNVFSDTLKFFGKPISRVENYCATGMDNIRNAAFAVASGAYDLVIAAGVEKLMDA--- 148 Query: 120 DATRYLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPY 179 +R L VS A+ A+ +G+T EDLA+ AV H NGA++P Sbjct: 149 -GSRGLPPIEGIFSVAMPYVSAPAMFAMAANRAFKEWGWTREDLAMVAVKNHYNGARHPK 207 Query: 180 AMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAG 239 A F+ +TVE V+K+P +A PL ++D S V DGAAAV++T PE AKE I D + I Sbjct: 208 AHFRSEVTVEKVLKAPMVAYPLGVYDCSAVSDGAAAVVLTRPEIAKE--IVGDDYAVIKA 265 Query: 240 MGRAIDTINLANR--EDLLTLKAAKIAAEKAYKMAKVE--PKDIDFFEVHDAFTVMAALS 295 +G A++T++ +R E L+ A AA+ AYKMA +E K++DF VHD FT+ ++ Sbjct: 266 VGMAVETMHPWHRPSESFLSFPATVKAAKMAYKMAGIENPRKELDFGIVHDCFTITELIN 325 Query: 296 LEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGE 355 + + + + GEGA+L + G AIDGD+PI GGLK+ GHP+ A+GV E Q+ G+ Sbjct: 326 YQDMQLCKPGEGAELIRNGVTAIDGDFPINPDGGLKSFGHPIAASGVRMVAELTKQVLGK 385 Query: 356 APNGIQVPDAEIGLTQNIGGTGSNITVTILRR 387 A G+QV DAE G N+GG S TV I+ R Sbjct: 386 A-EGLQVKDAEAGFAHNLGGPYSVATVAIVSR 416 >gb|AAK42810.1| Acetyl-CoA c-acetyltransferase (acetoacetyl-CoA thiolase) (acaB-8) [Sulfolobus solfataricus] Length = 376 Score = 234 bits (591), Expect = 1e-60 Identities = 141/379 (37%), Positives = 217/379 (57%), Gaps = 11/379 (2%) Query: 6 IVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVDSLYVGNMASGSFVEQENLGALI 65 I+ +T G+ + SL +LA E L + G ++D + V N SG F + LI Sbjct: 4 IIDASITRFGKR-KESLLELAGEVALPLI---GKYEIDFVVVSNSYSGEFNSLSGINNLI 59 Query: 66 ADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDATRYL 125 + + +P+++V+ SGG+A+ + S + VLV+GVEKM++ T + Sbjct: 60 TTYLSVDKVPSIRVDNTSGSGGSAILVAKSLLDSKITKTVLVLGVEKMSEKNTKQVTSVI 119 Query: 126 AYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYAMFKRP 185 A E E G++ +L L+ + YM Y + E AL AV H NG+ NP+A ++ Sbjct: 120 ASLLSPE-EKIVGLTLPSLAGLMTKEYMRRYNASREAFALVAVKNHYNGSLNPFAHIQKV 178 Query: 186 ITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMGRAID 245 +++E V+ SP IADPL L++ +P+ DGA+A+++ E A K V I GMG + D Sbjct: 179 VSLEEVLNSPIIADPLTLYEFTPISDGASAIVMVRDEDAYSF---TKKPVFIKGMGASSD 235 Query: 246 TINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALGVAEKG 305 T L+ RED+LT+ A +IA A KMAKV+ +DF E+HD TV+ + E LG+ +KG Sbjct: 236 TSYLSEREDILTMNAVRIAGLTARKMAKVDK--VDFAELHDMATVLEIVEAEELGLLKKG 293 Query: 306 EGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGIQVPDA 365 EG K + I+G+ PI T GGL ++GHP+GA+G+ Q VE+ LQIR +A QV +A Sbjct: 294 EGWKAYYDDYTKINGEMPINTSGGLNSKGHPIGASGIAQAVEAFLQIRNQA-GSRQVRNA 352 Query: 366 EIGLTQNIGGTGSNITVTI 384 +GL+ ++ G G++ TV I Sbjct: 353 RVGLSLSMAGFGNSATVII 371 >gi|11497639 3-ketoacyl-CoA thiolase (acaB-1) [Archaeoglobus fulgidus] >gi|7450463|pir||B69252 3-ketoacyl-CoA thiolase (acaB-1) homolog - Archaeoglobus fulgidus >gi|2650632|gb|AAB91208.1| (AE001105) 3-ketoacyl-CoA thiolase (acaB-1) [Archaeoglobus fulgidus] Length = 391 Score = 222 bits (561), Expect = 4e-57 Identities = 141/375 (37%), Positives = 206/375 (54%), Gaps = 12/375 (3%) Query: 7 VGVGMTPVGEHWRTSLRDLAVEAILKAMDDA-GIDK--VDSLYVGNMASGSFVEQENLGA 63 +G G+T G S +DL VEA DD +DK VDS ++G + Q ++ Sbjct: 1 MGAGITNFGRR-EASWKDLVVEAGKALFDDVPNLDKKDVDSFFIGAAQPERWTYQTHVAP 59 Query: 64 LIADWAGLGNIPAV-KVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDAT 122 L A+ G+ V + E+ACASG A++ AV SGL DV +VVGVEKM + + + Sbjct: 60 LAAELLGIKPRRVVARTESACASGQIAIRYAWLAVASGLSDVAVVVGVEKMNTKFMNLSQ 119 Query: 123 RYLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYAMF 182 + + E++ G++ A++ + +M+ YG TE+ +AL A + NPYA F Sbjct: 120 TSMMNVGNREFDTAMGLTAPPYFAMVAQRHMHLYGTTEDQMALVREKAGEYASANPYAQF 179 Query: 183 KRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMGR 242 ++ I+ E V+ S +A PLKL D S + DGAAA++IT EKA++ W+ + G+ R Sbjct: 180 QKKISKEDVLNSRMVAPPLKLLDCSGITDGAAALLITTEEKARKF-TDTPVWI-LGGIQR 237 Query: 243 AI-DTIN-LANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALG 300 + ++IN + D L+L + A+ Y + + P DID EVHD FT+ + E LG Sbjct: 238 TMANSINEMGEMSDWLSL---RYLAKDVYDLFNITPDDIDVAEVHDCFTISEIMEYEELG 294 Query: 301 VAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGI 360 +KGEG K +EGQ I G + GGL A GHP+GATGV Q E V+Q RGE P+ Sbjct: 295 FCKKGEGGKFIEEGQSYIGGKVAVNPSGGLLANGHPLGATGVRQAWEMVMQFRGEVPDKR 354 Query: 361 QVPDAEIGLTQNIGG 375 V AE+GL N+ G Sbjct: 355 YVSGAELGLAHNLSG 369 >pir||H72573 probable acetyl CoA synthase APE1872 - Aeropyrum pernix (strain K1) >gi|5105564|dbj|BAA80877.1| (AP000062) 407aa long hypothetical acetyl CoA synthase [Aeropyrum pernix] Length = 407 Score = 206 bits (519), Expect = 3e-52 Identities = 133/381 (34%), Positives = 202/381 (52%), Gaps = 15/381 (3%) Query: 6 IVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVDSLYVGNMASGSFVEQENLGALI 65 + VGM VG H+ + + +LA EA+ A+ DAG VD++ V + Q ++ + I Sbjct: 36 VKSVGMVKVGRHFSSGVEELAKEALESALSDAGWASVDAVVVSSFVYPRLSGQADIASYI 95 Query: 66 ADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDATRYL 125 G G A+ VEA ASG AA A+ G + V+++GV+KM+DA S L Sbjct: 96 VSSLGFGGATAITVEAGEASGLAAAVTAARLAAEGKK--VVLLGVDKMSDAPSSRVYSIL 153 Query: 126 AYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYAMFKRP 185 + +W+ + +S A++ L+ YM+ YG + L+ + H+N +NPYAM + Sbjct: 154 KGVYNIDWDGVYPISHAAIHGLLADMYMSRYGVDRDTLSYWPALMHSNAKENPYAMLRFA 213 Query: 186 ITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMGRAID 245 I E V + +A PL + D + DGAAAV ++ + G+ K VE A Sbjct: 214 IKPEAVKDAMPVALPLTMLDTFAMGDGAAAVTLS----RGDGGLAVLKAVEAAS-----G 264 Query: 246 TINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALGVAEKG 305 +++++ +D LT+ A K A +KA +A V +ID EVHD++T+ + LE+LG+AEKG Sbjct: 265 PLSISHLDDPLTMPAVKEAWDKARSLAGV--NNIDVLEVHDSYTITGIIILESLGLAEKG 322 Query: 306 EGAKLAKEGQIAIDGDYP-IQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGIQVPD 364 AK EG G+ P + GGLKARGH GATGVY E +Q+ G P G+ P Sbjct: 323 TAAKRVAEGYFTPSGEGPTVNASGGLKARGHSGGATGVYMLGEIAMQLAGVFP-GVNAPG 381 Query: 365 AEIGLTQNIGGTGSNITVTIL 385 A G +I G GS+ + +L Sbjct: 382 ARTGAAVSINGHGSSAYIAVL 402 >gb|AAF89837.1|AF173961_3 (AF173961) putative benzoylsuccinyl-CoA thiolase [Thauera aromatica] Length = 385 Score = 190 bits (478), Expect = 2e-47 Identities = 125/377 (33%), Positives = 181/377 (47%), Gaps = 16/377 (4%) Query: 3 KPIIVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDK---VDSLYVGNMASGSFVEQE 59 K I GVG T G H L A L+A+ + ID+ V S YVGN +G Q Sbjct: 6 KVYIAGVGETKFGRH-EVDFDVLGRAAALEALKASNIDRPTMVQSAYVGNGTNGMVTGQ- 63 Query: 60 NLGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPS 119 ++ D G++P + VE+AC++GG A+ + V GL DV + +G E T + Sbjct: 64 ---TVLKDLGMCGHLPIINVESACSAGGMAIHLAVRDVALGLADVAIGIGCENHT-LHMA 119 Query: 120 DATRYLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPY 179 T + SD E HG A+ + YM G T EDLA+ V + NPY Sbjct: 120 QGTAFATAMSDIE--TVHGAVMTGKYAMRAQRYMYETGATAEDLAMITVKNRRHATNNPY 177 Query: 180 AMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAG 239 A FK I++E V+ S +A PL L + DGA AV++ E K+LGI K I Sbjct: 178 AWFKGEISIEEVVNSRVVASPLTLQQCCGIADGAGAVVVCSEEMVKKLGIKKP----IRV 233 Query: 240 MGRAIDTINLANR-EDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEA 298 G + + NR D+ + A + Y+ + + P+D++ E+HDAFT+ L E Sbjct: 234 AGSVVRSGPYHNRPRDITGDDITEETAHQLYEESGIGPEDVNIVELHDAFTIAELLYYEC 293 Query: 299 LGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPN 358 LG+ KGEG K ++G G + GG+ + GHP+GA+G Q SV Q+R + P Sbjct: 294 LGLCPKGEGLKFLRDGNATHGGKCVVSPRGGMLSYGHPIGASGAAQIAASVKQMRNQCPG 353 Query: 359 GIQVPDAEIGLTQNIGG 375 P + +T GG Sbjct: 354 YQVEPVPRVAMTHVTGG 370 >emb|CAC11495.1| (AL445064) sterol carrier protein x/sterol carrier protein 2 related protein [Thermoplasma acidophilum] Length = 437 Score = 190 bits (477), Expect = 3e-47 Identities = 127/382 (33%), Positives = 193/382 (50%), Gaps = 32/382 (8%) Query: 33 AMDDAGIDKVD-SLYVGNMASGSFVEQENLGALIADWAGLGNIPAVKVEAACASGGAAVQ 91 AM+DAG+ D V + S F Q G ++ D+ GL P+ ++E A+GG A Q Sbjct: 55 AMNDAGLTLADIDGSVASYFSDHFQRQLMSGIMVQDYLGLVPKPSKRIEGGGATGGLAFQ 114 Query: 92 EGAKAVLSGLEDVVLVVGVEKMTDAWPSDATRYLAYASDAEWELFHGVSFVALNALIMRH 151 G + + SG D V V G E M+ ++A ASD ++ G + A++ Sbjct: 115 AGYEEIASGRMDTVAVYGFETMSHVNTWKGNEFIALASDTNFDYPIGGFYTGYYAMMAVR 174 Query: 152 YMNTYGYTEEDLALFAVNAHANGAKNPYAMFKRPITVETVMKSPYIADPLKLFDASPVCD 211 +M +G T E LA +V H N NPYA +TVE V +P ++ PL D + D Sbjct: 175 HMYEFGTTVEQLAKVSVKNHGNALHNPYAQSPMKLTVEDVRNAPMVSYPLTRLDVCAMSD 234 Query: 212 GAAAVIITIPEKAKELGIPKDKWVEIAGMGRAIDTINLANR----------------EDL 255 GAA I+ +KA E+ D V I G+G D++ LA+R +DL Sbjct: 235 GAAVAILASEDKAFEI---TDHPVLIKGIGTGTDSMRLADRPFGDVPLLPNEKPSDYKDL 291 Query: 256 L-----TLKAAKIAAEKAYKMAKVEP--KDIDFFEVHDAFTVMAALSLEALGVAEKGEGA 308 + +A ++AA++AY+MA + ++D E+HDA+T + E LG+ + GEG Sbjct: 292 KYPGVHSFRAGRMAAKEAYEMAGITDPLNELDLIELHDAYTSSEIQTYEDLGLCKYGEGG 351 Query: 309 KLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEA-----PNGIQVP 363 + EG+ + G P+ GGL A GHPVGATG+ Q V Q++ + +QVP Sbjct: 352 QFIDEGKPELHGKIPVNPSGGLLAAGHPVGATGIMQAVFMFWQLQHTIKKHFHDDYLQVP 411 Query: 364 DAEIGLTQNIGGTGSNITVTIL 385 +A+ GL + GTG+ +TVTI+ Sbjct: 412 NAKRGLIHSHAGTGTYVTVTIM 433 >gi|11497818 3-ketoacyl-CoA thiolase (acaB-6) [Archaeoglobus fulgidus] >gi|7450466|pir||B69275 3-ketoacyl-CoA thiolase (acaB-6) homolog - Archaeoglobus fulgidus >gi|2650440|gb|AAB91029.1| (AE001092) 3-ketoacyl-CoA thiolase (acaB-6) [Archaeoglobus fulgidus] Length = 380 Score = 189 bits (476), Expect = 4e-47 Identities = 135/385 (35%), Positives = 192/385 (49%), Gaps = 18/385 (4%) Query: 6 IVGVGMTPVGEHWRTSLRD-----LAVEAILKAMDDAGIDKVDSLYVGNMASGSFVEQEN 60 +VG G TP +RT +D LA EAI A+D AG++ D V F Sbjct: 5 VVGFGQTP----FRTKRKDKTHPELAFEAINAALDHAGLEMKDVEAVAYGCMDPFDGIYC 60 Query: 61 LGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSD 120 A AGL P +K+ +G + V SGL D+V+ V V+++ + D Sbjct: 61 PERWDATAAGLEK-PIMKISTGGTTGMTTALAAYEHVASGLFDLVMAVCVQRVGEC--VD 117 Query: 121 ATRYLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYA 180 A L A D +E G+ + + + YM YG TEEDLA +V H N KNPYA Sbjct: 118 AQPVLNTAVDPIYERHSGLGAIHVASFQATAYMAKYGATEEDLAWVSVKDHKNALKNPYA 177 Query: 181 MFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGM 240 K ++VE V+KS + PLKL + P DGAAAVI + A+++ +D + Sbjct: 178 HIKMDVSVEGVLKSRVVCSPLKLLECCPRSDGAAAVIFASEDVARKI---RDNPAWVVAE 234 Query: 241 GRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALG 300 D+ L +R + IA + +K A +EP +ID E++ FT+ L LEALG Sbjct: 235 TTISDSYYLGDRPSFAEWDSLAIAGRRLFKAAGIEPDEIDVAELYSPFTIQEILELEALG 294 Query: 301 VAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGI 360 A+KGEG A+EG +DGD+P GG+ +P+GATG+ + E+ LQ+ EA N Sbjct: 295 FAKKGEGKNFAREGVTFVDGDFPTNPSGGVLCT-NPIGATGLVRFGEAALQVMNEAKN-- 351 Query: 361 QVPDAEIGLTQNIGGTGSNITVTIL 385 QV AE+ L GGT T+ +L Sbjct: 352 QVDGAEVALAHAWGGTLQFHTLALL 376 >emb|CAB55378.1| (AL117263) possible 3-ketoacyl-CoA thiolase [Leishmania major] Length = 441 Score = 185 bits (464), Expect = 9e-46 Identities = 130/401 (32%), Positives = 199/401 (49%), Gaps = 28/401 (6%) Query: 15 GEHWRTSLRDLAVEAILKAMDDAGI----DKVDSLYVGNMASGSFVEQENLG-----ALI 65 G+ +L ++ + +++ G+ D VD + VGN F Q +LG +L Sbjct: 42 GKKQNMTLEEILATTVQHTIENTGLNGKEDIVDQVVVGNFLGELFSSQGHLGPAAIGSLT 101 Query: 66 ADWAGLGNI----PAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDA 121 AG N PA++VE ACASGG AV A+ +G D+ L VGVE T A Sbjct: 102 YGQAGAKNPLMYKPAMRVEGACASGGLAVVSATNALKAGSADIALAVGVEVQTTATARVG 161 Query: 122 TRYLAYASDAEWEL-FHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYA 180 YLA A+D + + +F L A M++ +T ED A A A+ANG +NP A Sbjct: 162 GDYLARAADYQRQRKLDDFTFPCLFAKRMKYIAEHNHFTMEDTARVAAKAYANGNRNPLA 221 Query: 181 -MFKRPITVETV----------MKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGI 229 M R ++ E + + + L++ D S V DG A V++ E K++G+ Sbjct: 222 HMHTRKLSFEQCNGEDPSNVKFLGNETYKEYLRMTDCSQVSDGGAGVVLANEEGLKKMGL 281 Query: 230 -PKD-KWVEIAGMGRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDA 287 P D + VEI + A+ + + +D + ++ AA+KA MA V+P D++ EVHD Sbjct: 282 SPNDSRLVEIKSIACAVSNL-YEDPDDACCMFTSRQAAQKALSMANVKPSDLNVAEVHDC 340 Query: 288 FTVMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVE 347 FT+ L EALG+AE G L + G+ ++G P+ T GGL + GHPVGATG+ Q +E Sbjct: 341 FTIAEMLMYEALGIAEYGHAKDLIRNGETTLEGRIPVNTGGGLLSFGHPVGATGIKQVME 400 Query: 348 SVLQIRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTILRRV 388 Q++G+ +G T N+GG +L+ + Sbjct: 401 VYRQMKGQCGAYQMKKIPALGATLNMGGDDKTAVSAVLQNI 441 >gb|AAK42246.1| Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) (acaB-3) [Sulfolobus solfataricus] Length = 409 Score = 172 bits (432), Expect = 5e-42 Identities = 129/385 (33%), Positives = 188/385 (48%), Gaps = 10/385 (2%) Query: 6 IVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGID--KVDSLYVGNMASGSFVEQENLGA 63 I+G G+T + +++A EA KA+D+AG++ +D + +G+ A +F G Sbjct: 30 IIGAGLTLFRRRLLETPQEIAWEAASKALDEAGLELKDIDCVVIGS-APDAFDGVNLKGE 88 Query: 64 LIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDATR 123 ++ AG P +V A+G G V SGL VL V EKM+ A P + Sbjct: 89 YLSHGAGGIKKPVSRVYVGGATGVMTAITGWYHVASGLCQKVLAVAEEKMSPARPHPQSI 148 Query: 124 YLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYAMFK 183 + Y D E + + + A+ M YM TYG +E++AL +V N NPYA Sbjct: 149 F-RYIWDPILEKPLNPNLIWIFAMEMHRYMATYGIKKEEIALVSVKNKRNAINNPYAQLG 207 Query: 184 RPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMGRA 243 ITVE V+KS + P++L D SPV DG AA+++ + A+ D V + G+G Sbjct: 208 SNITVEDVLKSEVLVWPVQLLDVSPVSDGGAAIVLASEDVARRY---TDTPVWVEGVGWT 264 Query: 244 IDTINLANREDLLTLKAAKIAAEKAYKMAKVE--PKDIDFFEVHDAFTVMAALSLEALGV 301 +D R DL + + AA AYKMA +E K+ID E +D F LEAL + Sbjct: 265 LDNTEWPAR-DLAYARYVEFAARMAYKMAGIERPNKEIDVAEPYDPFDYKELHHLEALQL 323 Query: 302 AEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGIQ 361 A++GE KL KEG IDGD P GGL G+P+ A G+ + + Q++G A Sbjct: 324 AKRGEAPKLLKEGVFDIDGDIPSSPSGGLLGVGNPIAAAGLMKVISIYWQLKGIAGKMQV 383 Query: 362 VPDAEIGLTQNIGGTGSNITVTILR 386 G+ Q G TV +LR Sbjct: 384 KRPVHTGVAQAWGDLMQAGTVIVLR 408 >pir||A39368 sterol carrier protein 2 precursor - rat >gi|202553|gb|AAA40622.1| (M62763) 60 kDa protein [Rattus norvegicus] Length = 547 Score = 169 bits (425), Expect = 3e-41 Identities = 129/404 (31%), Positives = 194/404 (47%), Gaps = 28/404 (6%) Query: 1 MEKPIIVGVGMT----PVGEHWRTSLRDLAVEAILKAMDDAGI--DKVDSLYVGNMASGS 54 + + +VGVGMT P GE+ R DLA EA KA+ DA I V+ VG + S Sbjct: 11 LRRVFVVGVGMTKFMKPGGENSR-DYPDLAKEAGQKALADAQIPYSAVEQACVGYVYGES 69 Query: 55 FVEQENLGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMT 114 Q I GL IP + V C++G A+ + V GL + VL +G EKM Sbjct: 70 TCGQR----AIYHSLGLTGIPIINVNNNCSTGSTALFMAQQLVQGGLANCVLALGFEKME 125 Query: 115 DAWPSDATRYLAYASDAEWELFHGVSFVALNALIM---------RHYMNTYGYTEEDLAL 165 S T+Y ++ E + ++ ++A + +M TYG E A Sbjct: 126 KG--SLGTKYSDRSNPLEKHIDVLINKYGMSACPFAPQLFGSAGKEHMETYGTKVEHFAK 183 Query: 166 FAVNAHANGAKNPYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAK 225 H + NPY+ F+ +++ +MKS + D L + P DGAAA I++ E + Sbjct: 184 IGWKNHKHSVNNPYSQFQDEYSLDEIMKSRPVFDFLTVLQCCPTSDGAAAAIVSSEEFVQ 243 Query: 226 ELGIPKDKWVEIAGMGRAIDTINLANREDLLTLKA---AKIAAEKAYKMAKVEPKDIDFF 282 + G+ + K VEI D + + ++ + +K AA K Y+ + + P D+D Sbjct: 244 KHGL-QSKAVEIVAQEMVTDMPSTFEEKSVIKMVGYDMSKEAARKCYEKSGLGPSDVDVI 302 Query: 283 EVHDAFTVMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGV 342 E+HD F+ L+ EALG+ +G+G L G G + I GGL ++GHP+GATG+ Sbjct: 303 ELHDCFSTNELLTYEALGLCPEGQGGALVDRGDNTYGGKWVINPSGGLISKGHPLGATGL 362 Query: 343 YQTVESVLQIRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTILR 386 Q E Q+RGEA QVP A++ L N+ G G VT+ R Sbjct: 363 AQCAELCWQLRGEAGKR-QVPGAKVALQHNL-GLGGAAVVTLYR 404 >pir||E70884 probable lipid-transfer protein - Mycobacterium tuberculosis (strain H37RV) >gi|2624312|emb|CAA15585.1| (AL008967) ltp1 [Mycobacterium tuberculosis] Length = 401 Score = 168 bits (421), Expect = 1e-40 Identities = 126/399 (31%), Positives = 186/399 (46%), Gaps = 24/399 (6%) Query: 3 KPIIVGVGMTPVGEHWRTS---LRDLAVEAILKAMDDAGID--KVDSLYVGNMASGSFVE 57 K ++GVGMT + R D+A E+ KA+ DAGID +V+ YVG + S Sbjct: 9 KVYVIGVGMTKFEKPGRREGWDYPDMARESGTKALRDAGIDYREVEQGYVGYVYGESTSG 68 Query: 58 QENLGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKM---- 113 Q L L G+ IP V V C++G A+ GA+A+ GL D VL +G EKM Sbjct: 69 QRALYEL-----GMTGIPIVNVNNNCSTGSTALYLGAQAIRGGLADCVLALGFEKMQPGA 123 Query: 114 ----TDAWPSDATRYLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVN 169 D S R++ + AE + F + R +M YG T E A Sbjct: 124 LGGGADDRESPLGRHV--KALAEIDEFGFPVAPWMFGAAGREHMKKYGTTAEHFAKIGYK 181 Query: 170 AHANGAKNPYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGI 229 H + NPYA F+ T++ ++ S I+DPL SP DG+AAV++ + + Sbjct: 182 NHKHSVNNPYAQFQDEYTLDDILASKMISDPLTKLQCSPTSDGSAAVVLASEDYLANHNL 241 Query: 230 PKDKWVEIAGMGRAIDTINL--ANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDA 287 + VEI G D + + +++ AA++ Y+ + + PKD E+HD Sbjct: 242 -AGRAVEIVGQAMTTDFASTFDGSARNIIGYDMTVQAAQRVYQQSGLGPKDFGVIELHDC 300 Query: 288 FTVMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVE 347 F+ L EALG+ GE +L + Q G + + GGL ++GHP+GATG+ Q E Sbjct: 301 FSANELLLYEALGLCGPGEAPELIDDNQTTYGGRWVVNPSGGLISKGHPLGATGLAQCAE 360 Query: 348 SVLQIRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTILR 386 Q+RG A QV + L NIG G+ + R Sbjct: 361 LTWQLRGTA-EARQVDNVTAALQHNIGLGGAAVVTAYQR 398 >emb|CAA43061.1| (X60654) open reading frame for 58 kDa protein containing the non-specific lipid transfer protein [Rattus norvegicus] Length = 546 Score = 168 bits (420), Expect = 1e-40 Identities = 128/404 (31%), Positives = 193/404 (47%), Gaps = 28/404 (6%) Query: 1 MEKPIIVGVGMT----PVGEHWRTSLRDLAVEAILKAMDDAGI--DKVDSLYVGNMASGS 54 + + +VGVGMT P GE+ R DLA EA KA+ D I V+ VG + S Sbjct: 10 LRRVFVVGVGMTKFMKPGGENSR-DYPDLAKEAGQKALADRQIPYSAVEQACVGYVYGES 68 Query: 55 FVEQENLGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMT 114 Q I GL IP + V C++G A+ + V GL + VL +G EKM Sbjct: 69 TCGQR----AIYHSLGLTGIPIINVNNNCSTGSTALFMAQQLVQGGLANCVLALGFEKME 124 Query: 115 DAWPSDATRYLAYASDAEWELFHGVSFVALNALIM---------RHYMNTYGYTEEDLAL 165 S T+Y ++ E + ++ ++A + +M TYG E A Sbjct: 125 KG--SLGTKYSDRSNPLEKHIDVLINKYGMSACPFAPQLFGSAGKEHMETYGTKVEHFAK 182 Query: 166 FAVNAHANGAKNPYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAK 225 H + NPY+ F+ +++ +MKS + D L + P DGAAA I++ E + Sbjct: 183 IGWKNHKHSVNNPYSQFQDEYSLDEIMKSRPVFDFLTVLQCCPTSDGAAAAIVSSEEFVQ 242 Query: 226 ELGIPKDKWVEIAGMGRAIDTINLANREDLLTLKA---AKIAAEKAYKMAKVEPKDIDFF 282 + G+ + K VEI D + + ++ + +K AA K Y+ + + P D+D Sbjct: 243 KHGL-QSKAVEIVAQEMVTDMPSTFEEKSVIKMVGYDMSKEAARKCYEKSGLGPSDVDVI 301 Query: 283 EVHDAFTVMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGV 342 E+HD F+ L+ EALG+ +G+G L G G + I GGL ++GHP+GATG+ Sbjct: 302 ELHDCFSTNELLTYEALGLCPEGQGGALVDRGDNTYGGKWVINPSGGLISKGHPLGATGL 361 Query: 343 YQTVESVLQIRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTILR 386 Q E Q+RGEA QVP A++ L N+ G G VT+ R Sbjct: 362 AQCAELCWQLRGEAGKR-QVPGAKVALQHNL-GLGGAAVVTLYR 403 >gb|AAB27044.1| 3-oxoacyl-CoA thiolase homolog {N-terminal} [rats, Peptide Partial, 405 aa] Length = 405 Score = 168 bits (420), Expect = 1e-40 Identities = 128/404 (31%), Positives = 193/404 (47%), Gaps = 28/404 (6%) Query: 1 MEKPIIVGVGMT----PVGEHWRTSLRDLAVEAILKAMDDAGI--DKVDSLYVGNMASGS 54 + + +VGVGMT P GE+ R DLA EA KA+ D I V+ VG + S Sbjct: 10 LRRVFVVGVGMTKFMKPGGENSR-DYPDLAKEAGQKALADRQIPYSAVEQACVGYVYGES 68 Query: 55 FVEQENLGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMT 114 Q I GL IP + V C++G A+ + V GL + VL +G EKM Sbjct: 69 TCGQR----AIYHSLGLTGIPIINVNNNCSTGSTALFMAQQLVQGGLANCVLALGFEKME 124 Query: 115 DAWPSDATRYLAYASDAEWELFHGVSFVALNALIM---------RHYMNTYGYTEEDLAL 165 S T+Y ++ E + ++ ++A + +M TYG E A Sbjct: 125 KG--SLGTKYSDRSNPLEKHIDVLINKYGMSACPFAPQLFGSAGKEHMETYGTKVEHFAK 182 Query: 166 FAVNAHANGAKNPYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAK 225 H + NPY+ F+ +++ +MKS + D L + P DGAAA I++ E + Sbjct: 183 IGWKNHKHSVNNPYSQFQDEYSLDEIMKSRPVFDFLTVLQCCPTSDGAAAAIVSSEEFVQ 242 Query: 226 ELGIPKDKWVEIAGMGRAIDTINLANREDLLTLKA---AKIAAEKAYKMAKVEPKDIDFF 282 + G+ + K VEI D + + ++ + +K AA K Y+ + + P D+D Sbjct: 243 KHGL-QSKAVEIVAQEMVTDMPSTFEEKSVIKMVGYDMSKEAARKCYEKSGLGPSDVDVI 301 Query: 283 EVHDAFTVMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGV 342 E+HD F+ L+ EALG+ +G+G L G G + I GGL ++GHP+GATG+ Sbjct: 302 ELHDCFSTNELLTYEALGLCPEGQGGALVDRGDNTYGGKWVINPSGGLISKGHPLGATGL 361 Query: 343 YQTVESVLQIRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTILR 386 Q E Q+RGEA QVP A++ L N+ G G VT+ R Sbjct: 362 AQCAELCWQLRGEAGKR-QVPGAKVALQHNL-GLGGAAVVTLYR 403 >sp|P11915|NLTP_RAT NONSPECIFIC LIPID-TRANSFER PROTEIN PRECURSOR (NSL-TP) (STEROL CARRIER PROTEIN 2) (SCP-2) (STEROL CARRIER PROTEIN X) (SCP-X) (SCPX) Length = 547 Score = 167 bits (419), Expect = 2e-40 Identities = 128/404 (31%), Positives = 193/404 (47%), Gaps = 28/404 (6%) Query: 1 MEKPIIVGVGMT----PVGEHWRTSLRDLAVEAILKAMDDAGI--DKVDSLYVGNMASGS 54 + + +VGVGMT P GE+ R DLA EA KA+ D I V+ VG + S Sbjct: 11 LPRVFVVGVGMTKFMKPGGENSR-DYPDLAKEAGQKALADRQIPYSAVEQACVGYVYGES 69 Query: 55 FVEQENLGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMT 114 Q I GL IP + V C++G A+ + V GL + VL +G EKM Sbjct: 70 TCGQR----AIYHSLGLTGIPIINVNNNCSTGSTALFMAQQLVQGGLANCVLALGFEKME 125 Query: 115 DAWPSDATRYLAYASDAEWELFHGVSFVALNALIM---------RHYMNTYGYTEEDLAL 165 S T+Y ++ E + ++ ++A + +M TYG E A Sbjct: 126 KG--SLGTKYSDRSNPLEKHIDVLINKYGMSACPFAPQLFGSAGKEHMETYGTKVEHFAK 183 Query: 166 FAVNAHANGAKNPYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAK 225 H + NPY+ F+ +++ +MKS + D L + P DGAAA I++ E + Sbjct: 184 IGWKNHKHSVNNPYSQFQDEYSLDEIMKSRPVFDFLTVLQCCPTSDGAAAAIVSSEEFVQ 243 Query: 226 ELGIPKDKWVEIAGMGRAIDTINLANREDLLTLKA---AKIAAEKAYKMAKVEPKDIDFF 282 + G+ + K VEI D + + ++ + +K AA K Y+ + + P D+D Sbjct: 244 KHGL-QSKAVEIVAQEMVTDMPSTFEEKSVIKMVGYDMSKEAARKCYEKSGLGPSDVDVI 302 Query: 283 EVHDAFTVMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGV 342 E+HD F+ L+ EALG+ +G+G L G G + I GGL ++GHP+GATG+ Sbjct: 303 ELHDCFSTNELLTYEALGLCPEGQGGALVDRGDNTYGGKWVINPSGGLISKGHPLGATGL 362 Query: 343 YQTVESVLQIRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTILR 386 Q E Q+RGEA QVP A++ L N+ G G VT+ R Sbjct: 363 AQCAELCWQLRGEAGKR-QVPGAKVALQHNL-GLGGAAVVTLYR 404 >pir||A70559 hypothetical protein Rv1627c - Mycobacterium tuberculosis (strain H37RV) >gi|2113911|emb|CAB08880.1| (Z95554) hypothetical protein Rv1627c [Mycobacterium tuberculosis] Length = 402 Score = 167 bits (419), Expect = 2e-40 Identities = 132/417 (31%), Positives = 193/417 (45%), Gaps = 59/417 (14%) Query: 2 EKPIIVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGID-----------KVDSLYVGNM 50 E I+G GM P G+ W + V A A+ DAG+D + + Y G + Sbjct: 7 EPVYILGAGMHPWGK-WGNDFTEYGVVAARAALRDAGVDWRHVQLVAGADTIRNGYPGFV 65 Query: 51 ASGSFVEQENLGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGV 110 A +F ++ LG W G +P AACASG A+Q +L+G DV LV+G Sbjct: 66 AGATFAQK--LG-----WTG---VPVSSSYAACASGSQALQSARAQILAGFCDVALVIGA 115 Query: 111 EKMTDAW--PSDATRYLAYASDAEWELFH--GVSFVALNALIMRHYMNTYGYTEEDLALF 166 + + P R D +W+ FH G + AL+ R M+ YG T ED A Sbjct: 116 DTTPKGFFAPVGGER----KGDPDWQRFHLIGATNTVYFALLARRRMDLYGATVEDFAQV 171 Query: 167 AVNAHANGAKNPYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPE-KAK 225 V +G NP A +++ +++ V+ SP ++DPL+L D DGAAA+I+ K Sbjct: 172 KVKNSRHGLDNPNARYRKENSIDDVLASPVVSDPLRLLDICATSDGAAALIVASKSFTEK 231 Query: 226 ELGIPKDKWVEIAGMG--RAIDTI------NLANREDLLTLKAAKIAA----------EK 267 LG +AG+ RAI T+ +L D+ T A + A + Sbjct: 232 HLG-------SVAGVPSVRAISTVTPKYPQHLPELPDIATDSTAAVPAPERVFKDQILDA 284 Query: 268 AYKMAKVEPKDIDFFEVHDAFTVMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTM 327 AY A + P+D+ EV+D T + E LG+ KGE L + G + G P+ Sbjct: 285 AYAEAGIGPEDLSLAEVYDLSTALELDWYEHLGLCPKGEAEALLRSGATTLGGRVPVNPS 344 Query: 328 GGLKARGHPVGATGVYQTVESVLQIRGEAPNGIQVPDAEIGLTQNIG--GTGSNITV 382 GGL G + A + Q E Q+RG+A G QV DA++G+T N G G GS++ V Sbjct: 345 GGLACFGEAIPAQAIAQVCELTWQLRGQA-TGRQVADAKVGVTANQGLFGHGSSVIV 400 >gb|AAA42122.1| (M57453) sterol carrier protein-x [Rattus norvegicus] Length = 547 Score = 167 bits (418), Expect = 2e-40 Identities = 128/404 (31%), Positives = 192/404 (46%), Gaps = 28/404 (6%) Query: 1 MEKPIIVGVGMT----PVGEHWRTSLRDLAVEAILKAMDDAGI--DKVDSLYVGNMASGS 54 + + +VGVGMT P GE+ R DLA EA KA+ D I V+ VG + S Sbjct: 11 LPRVFVVGVGMTKFMKPGGENSR-DYPDLAKEAGQKALADRQIPYSAVEQACVGYVYGES 69 Query: 55 FVEQENLGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMT 114 Q I GL IP + V C++G A+ + V GL + VL +G EKM Sbjct: 70 TCGQR----AIYHSLGLTGIPIINVNNNCSTGSTALFMAQQLVQGGLANCVLALGFEKME 125 Query: 115 DAWPSDATRYLAYASDAEWELFHGVSFVALNALIM---------RHYMNTYGYTEEDLAL 165 S T+Y ++ E + ++ ++A + +M TYG E A Sbjct: 126 KG--SLGTKYSDRSNPLEKHIDVLINKYGMSACPFAPQLFGSAGKEHMETYGTKVEHFAK 183 Query: 166 FAVNAHANGAKNPYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAK 225 H + NPY+ F+ +++ +MKS + D L + P DGAAA I++ E + Sbjct: 184 IGWKNHKHSVNNPYSQFQDEYSLDEIMKSRPVFDFLTVLQCCPTSDGAAAAIVSSEEFVQ 243 Query: 226 ELGIPKDKWVEIAGMGRAIDTINLANREDLLTLKA---AKIAAEKAYKMAKVEPKDIDFF 282 + G+ + K VEI D + ++ + +K AA K Y+ + + P D+D Sbjct: 244 KHGL-QSKAVEIVAQEMVTDMPTTFEEKSVIKMVGYDMSKEAARKCYEKSGLGPSDVDVI 302 Query: 283 EVHDAFTVMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGV 342 E+HD F+ L+ EALG+ +G+G L G G + I GGL ++GHP+GATG+ Sbjct: 303 ELHDCFSTNELLTYEALGLCPEGQGGALVDRGDNTYGGKWVINPSGGLISKGHPLGATGL 362 Query: 343 YQTVESVLQIRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTILR 386 Q E Q+RGEA QVP A++ L N+ G G VT+ R Sbjct: 363 AQCAELCWQLRGEAGKR-QVPGAKVALQHNL-GLGGAAVVTLYR 404 >sp|P32020|NLTP_MOUSE NONSPECIFIC LIPID-TRANSFER PROTEIN PRECURSOR (NSL-TP) (STEROL CARRIER PROTEIN 2) (SCP-2) (STEROL CARRIER PROTEIN X) (SCP-X) (SCPX) >gi|420230|pir||JU0157 sterol carrier protein x - mouse >gi|293794|gb|AAA40098.1| (M91458) sterol-carrier protein X [Mus musculus] Length = 547 Score = 165 bits (413), Expect = 9e-40 Identities = 124/402 (30%), Positives = 191/402 (46%), Gaps = 24/402 (5%) Query: 1 MEKPIIVGVGMT----PVGEHWRTSLRDLAVEAILKAMDDAGI--DKVDSLYVGNMASGS 54 + + +VGVGMT P GE+ R D+A EA KA++DA I V+ VG + S Sbjct: 11 LRRVFVVGVGMTKFMKPGGENSR-DYPDMAKEAGQKALEDAQIPYSAVEQACVGYVYGDS 69 Query: 55 FVEQENLGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMT 114 Q I GL IP + V C++G A+ + + GL + VL +G EKM Sbjct: 70 TSGQR----AIYHSLGLTGIPIINVNNNCSTGSTALFMAHQLIQGGLANCVLALGFEKME 125 Query: 115 DAWPSDATRYLAYASDAEWELF---HGVSFVALNALIM----RHYMNTYGYTEEDLALFA 167 +D E+ +G+S + + + +M YG E A Sbjct: 126 RGSIGTKFSDRTTPTDKHIEVLIDKYGLSAHPITPQMFGYAGKEHMEKYGTKVEHFAKIG 185 Query: 168 VNAHANGAKNPYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKEL 227 H + N Y+ F+ ++E VMKS + D L + P DGA A I++ E ++ Sbjct: 186 WKNHKHSVNNTYSQFQDEYSLEEVMKSKPVFDFLTILQCCPTSDGACAAILSSEEFVQQY 245 Query: 228 GIPKDKWVEIAGMGRAIDTINLANREDLLTLKA---AKIAAEKAYKMAKVEPKDIDFFEV 284 G+ + K VEI D + + ++ + +K AA + Y+ + + P D+D E+ Sbjct: 246 GL-QSKAVEIVAQEMMTDLPSTFEEKSIIKVVGYDMSKEAARRCYEKSGLTPNDVDVIEL 304 Query: 285 HDAFTVMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQ 344 HD F+V ++ EALG+ +G+G L G G + I GGL ++GHP+GATG+ Q Sbjct: 305 HDCFSVNELITYEALGLCPEGQGGTLVDRGDNTYGGKWVINPSGGLISKGHPLGATGLAQ 364 Query: 345 TVESVLQIRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTILR 386 E Q+RGEA QVP A++ L N+ G G + VT+ R Sbjct: 365 CAELCWQLRGEAGKR-QVPGAKVALQHNL-GLGGAVVVTLYR 404 >gi|11498572 3-ketoacyl-CoA thiolase (acaB-9) [Archaeoglobus fulgidus] >gi|7450469|pir||G69370 3-ketoacyl-CoA thiolase (acaB-9) homolog - Archaeoglobus fulgidus >gi|2649647|gb|AAB90276.1| (AE001038) 3-ketoacyl-CoA thiolase (acaB-9) [Archaeoglobus fulgidus] Length = 400 Score = 163 bits (408), Expect = 3e-39 Identities = 128/384 (33%), Positives = 188/384 (48%), Gaps = 10/384 (2%) Query: 6 IVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAG--IDKVDSLYVGNMASGSFVEQENLGA 63 IVG GMT + R+L+ A+ +A+++AG ID ++ + +G+ A +F G Sbjct: 19 IVGAGMTTFKRRLNETGRELSYLAVKQALEEAGLTIDDIEMVVMGS-APDAFDGFHMKGE 77 Query: 64 LIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDATR 123 + D +G N P ++V +G A G V SGL DV LVV EKM+ P + Sbjct: 78 YLLDGSGGSNRPYMRVFVGGGTGVFAPIAGYWHVASGLADVCLVVCEEKMSSVHPHPQSA 137 Query: 124 YLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYAMFK 183 + Y D + + + + AL MR YM+ + ED+AL +V AN +P A Sbjct: 138 F-KYIWDPILDRPLNPNLIWIFALEMRRYMHVHNIKHEDIALVSVKNKANALDHPCAQVA 196 Query: 184 RPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMGRA 243 ITVE V+ S +A P++ D SP DGAAA+I+ P A++L D V + G+G A Sbjct: 197 EKITVEDVLNSEPMALPVRRLDVSPPSDGAAALIMVAPHIARQL---TDNPVWVTGVGWA 253 Query: 244 IDTINLANREDLLTLKAAKIAAEKAYKMAKVEP--KDIDFFEVHDAFTVMAALSLEALGV 301 +DT NR DL + AA+ AY+MA + K+ID E +D F +E LG+ Sbjct: 254 LDTTWWTNR-DLYFPRYVAEAAKMAYRMAHITDPRKEIDVAEPYDPFDYKELHHMEGLGL 312 Query: 302 AEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGIQ 361 A+KGE L +EG DGD P GGL G+P+ AT + E Q+ A Sbjct: 313 AKKGEAPILTREGVTQRDGDLPTCPSGGLLGVGNPIAATMGVKACEIYWQLAYRAGKRQV 372 Query: 362 VPDAEIGLTQNIGGTGSNITVTIL 385 + G+ Q G TV ++ Sbjct: 373 AKEVTTGVCQAWGDLMQVGTVMVM 396 >sp|P22307|NLTP_HUMAN NONSPECIFIC LIPID-TRANSFER PROTEIN PRECURSOR (NSL-TP) (STEROL CARRIER PROTEIN 2) (SCP-2) (STEROL CARRIER PROTEIN X) (SCP-X) (SCPX) >gi|2136204|pir||I38205 sterol carrier protein-X/sterol carrier protein-2 - human >gi|432975|gb|AAA03557.1| (M75883) sterol carrier protein-X/sterol carrier protein-2 [Homo sapiens] Length = 547 Score = 162 bits (406), Expect = 6e-39 Identities = 125/402 (31%), Positives = 189/402 (46%), Gaps = 24/402 (5%) Query: 1 MEKPIIVGVGMT----PVGEHWRTSLRDLAVEAILKAMDDAGI--DKVDSLYVGNMASGS 54 + + +VGVGMT P E+ R DLA EA KA+ DA I VD VG + S Sbjct: 11 LRRVFVVGVGMTKFVKPGAENSR-DYPDLAEEAGKKALADAQIPYSAVDQACVGYVFGDS 69 Query: 55 FVEQENLGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMT 114 Q I G+ IP + V CA+G A+ + + G+ + VL +G EKM+ Sbjct: 70 TCGQR----AIYHSLGMTGIPIINVNNNCATGSTALFMARQLIQGGVAECVLALGFEKMS 125 Query: 115 DAWPSDATRYLAYASDAEWELF---HGVSFVALNALIM----RHYMNTYGYTEEDLALFA 167 +D +L +G+S + + + +M YG E A Sbjct: 126 KGSLGIKFSDRTIPTDKHVDLLINKYGLSAHPVAPQMFGYAGKEHMEKYGTKIEHFAKIG 185 Query: 168 VNAHANGAKNPYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKEL 227 H + NPY+ F+ +++ VM S + D L + P DGAAA I+ ++ Sbjct: 186 WKNHKHSVNNPYSQFQDEYSLDEVMASKEVFDFLTILQCCPTSDGAAAAILASEAFVQKY 245 Query: 228 GIPKDKWVEIAGMGRAIDTINLANREDLLTLKA---AKIAAEKAYKMAKVEPKDIDFFEV 284 G+ + K VEI D + + ++ + +K AA K Y+ + + P DID E+ Sbjct: 246 GL-QSKAVEILAQEMMTDLPSSFEEKSIIKMVGFDMSKEAARKCYEKSGLTPNDIDVIEL 304 Query: 285 HDAFTVMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQ 344 HD F+ L+ EALG+ +G+GA L G G + I GGL ++GHP+GATG+ Q Sbjct: 305 HDCFSTNELLTYEALGLCPEGQGATLVDRGDNTYGGKWVINPSGGLISKGHPLGATGLAQ 364 Query: 345 TVESVLQIRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTILR 386 E Q+RGEA QVP A++ L N+ G G + VT+ + Sbjct: 365 CAELCWQLRGEAGKR-QVPGAKVALQHNL-GIGGAVVVTLYK 404 >gb|AAB41286.1| (U11313) sterol carrier protein-X/sterol carrier protein-2 [Homo sapiens] Length = 547 Score = 159 bits (399), Expect = 4e-38 Identities = 124/402 (30%), Positives = 188/402 (45%), Gaps = 24/402 (5%) Query: 1 MEKPIIVGVGMT----PVGEHWRTSLRDLAVEAILKAMDDAGI--DKVDSLYVGNMASGS 54 + + +VGVGMT P E+ R DLA EA KA+ DA I VD VG + S Sbjct: 11 LRRVFVVGVGMTKFVKPGAENSR-DYPDLAEEAGKKALADAQIPYSAVDQACVGYVFGDS 69 Query: 55 FVEQENLGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMT 114 Q I G+ IP + V CA+G A+ + + G+ + VL +G EKM+ Sbjct: 70 TCGQR----AIYHSLGMTGIPIINVNNNCATGSTALFMARQLIQGGVAECVLALGFEKMS 125 Query: 115 DAWPSDATRYLAYASDAEWELF---HGVSFVALNALIM----RHYMNTYGYTEEDLALFA 167 +D +L +G+S + + + +M YG E A Sbjct: 126 KGSLGIKFSDRTIPTDKHVDLLINKYGLSAHPVAPQMFGYAGKEHMEKYGTKIEHFAKIG 185 Query: 168 VNAHANGAKNPYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKEL 227 H + NPY+ F+ +++ VM S + D L + P DGAAA I+ ++ Sbjct: 186 WKNHKHSVNNPYSQFQDEYSLDEVMASKEVFDFLTILQCCPTSDGAAAAILASEAFVQKY 245 Query: 228 GIPKDKWVEIAGMGRAIDTINLANREDLLTLKA---AKIAAEKAYKMAKVEPKDIDFFEV 284 G+ + K VEI D + + ++ + +K AA K Y+ + + P DID E+ Sbjct: 246 GL-QSKAVEILAQEMMTDLPSSFEEKSIIKMVGFDMSKEAARKCYEKSGLTPNDIDVIEL 304 Query: 285 HDAFTVMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQ 344 HD F+ L+ EALG+ +G+GA L G G + I GGL ++GHP+GATG+ Q Sbjct: 305 HDCFSTNELLTYEALGLCPEGQGATLVDRGDNTYGGKWVINPSGGLISKGHPLGATGLAQ 364 Query: 345 TVESVLQIRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTILR 386 E Q+RGEA QVP A++ L N+ G + VT+ + Sbjct: 365 CAELCWQLRGEAGKR-QVPGAKVALQHNL-DIGGAVVVTLYK 404 >gb|AAC15422.1| (AF051897) sterol carrier protein X [Oryctolagus cuniculus] Length = 547 Score = 159 bits (397), Expect = 7e-38 Identities = 119/397 (29%), Positives = 187/397 (46%), Gaps = 25/397 (6%) Query: 1 MEKPIIVGVGMTPVGEHWRTSLRD---LAVEAILKAMDDAGI--DKVDSLYVGNMASGSF 55 + + +VGVGMT + RD +A EA KA+ DA I V+ +G + S Sbjct: 11 LPRVFVVGVGMTKFVKPGTEDARDYPDMAKEAGQKALADAQIPYSAVEQACIGYVYGDST 70 Query: 56 VEQENLGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTD 115 Q + GL IP + V C++G A+ G + + G+ + VL +G EKM Sbjct: 71 CGQR----AVYHSLGLTGIPIINVNNNCSTGSTALFMGRQLIQGGMAECVLALGFEKMER 126 Query: 116 AWPSDATRYLAYASDAEWELFHGVSFVALNALIM---------RHYMNTYGYTEEDLALF 166 S ++ + + L ++ L+A + + +M YG E A Sbjct: 127 G--SLGAKFPDRTNPMDKHLDVLINKYGLSAHPVAPQMFGSAGKEHMEKYGTKIEHFAKI 184 Query: 167 AVNAHANGAKNPYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKE 226 H + NPY+ F++ +++ VM S I D L + P DGAAA I+ E K+ Sbjct: 185 GWKNHKHSVNNPYSQFQKEYSLDEVMSSRPIFDFLTVLQCCPTSDGAAAAILASEEFVKK 244 Query: 227 LGIPKDKWVEIAGMGRAIDTINLANREDLLTLKA---AKIAAEKAYKMAKVEPKDIDFFE 283 G+ + K VEI D + + ++ + +K AA + Y+ + + P DID E Sbjct: 245 YGL-QSKAVEILAQEMVTDFPSSFEEKSIIKMVGFDMSKEAARRCYEKSGLRPSDIDVIE 303 Query: 284 VHDAFTVMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVY 343 +HD F+ L+ EALG+ +G+G L G G + I GGL ++GHP+GATG+ Sbjct: 304 LHDCFSANELLTYEALGLCPEGKGGALVDRGDNTYGGKWVINPSGGLISKGHPLGATGLA 363 Query: 344 QTVESVLQIRGEAPNGIQVPDAEIGLTQNIGGTGSNI 380 Q E Q+RGEA QVP A++ L N+G G+ + Sbjct: 364 QCAELCWQLRGEAGKR-QVPGAKVALQHNLGLGGAAV 399 >pir||A34635 nonspecific lipid transfer protein precursor - rat (fragment) >gi|205770|gb|AAA41726.1| (M58287) non-specific lipid transfer protein [Rattus sp.] Length = 515 Score = 159 bits (397), Expect = 7e-38 Identities = 118/377 (31%), Positives = 179/377 (47%), Gaps = 23/377 (6%) Query: 24 DLAVEAILKAMDDAGI--DKVDSLYVGNMASGSFVEQENLGALIADWAGLGNIPAVKVEA 81 DLA EA KA+ D I V+ VG + S Q I GL IP + V Sbjct: 5 DLAKEAGQKALADRQIPYSAVEQACVGYVYGESTCGQR----AIYHSLGLTGIPIINVNN 60 Query: 82 ACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDATRYLAYASDAEWELFHGVSF 141 C++G A+ + V GL + VL +G EKM S T+Y ++ E + ++ Sbjct: 61 NCSTGSTALFMAQQLVQGGLANCVLALGFEKMEKG--SLGTKYSDRSNPLEKHIDVLINK 118 Query: 142 VALNALIM---------RHYMNTYGYTEEDLALFAVNAHANGAKNPYAMFKRPITVETVM 192 ++A + +M TYG E A H + NPY+ F+ +++ +M Sbjct: 119 YGMSACPFAPQLFGSAGKEHMETYGTKVEHFAKIGWKNHKHSVNNPYSQFQDEYSLDEIM 178 Query: 193 KSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMGRAIDTINLANR 252 KS + D L + P DGAAA I++ E ++ G+ + K VEI D + Sbjct: 179 KSRPVFDFLTVLQCCPTSDGAAAAIVSSEEFVQKHGL-QSKAVEIVAQEMVTDMPSTFEE 237 Query: 253 EDLLTLKA---AKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALGVAEKGEGAK 309 + ++ + +K AA K Y+ + + P D+D E+HD F+ L+ EALG+ +G+G Sbjct: 238 KSVIKMVGYDMSKEAARKCYEKSGLGPSDVDVIELHDCFSTNELLTYEALGLCPEGQGGA 297 Query: 310 LAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGIQVPDAEIGL 369 L G G + I GGL ++GHP+GATG+ Q E Q+RGEA QVP A++ L Sbjct: 298 LVDRGDNTYGGKWVINPSGGLISKGHPLGATGLAQCAELCWQLRGEAGKR-QVPGAKVAL 356 Query: 370 TQNIGGTGSNITVTILR 386 N+ G G VT+ R Sbjct: 357 QHNL-GLGGAAVVTLYR 372 >gb|AAF53713.1| (AE003660) ScpX gene product [Drosophila melanogaster] Length = 544 Score = 157 bits (394), Expect = 2e-37 Identities = 116/397 (29%), Positives = 181/397 (45%), Gaps = 24/397 (6%) Query: 6 IVGVGMTPVGEHWRTS---LRDLAVEAILKAMDDAGIDKVDSLYVGNMASGSFVEQENLG 62 +VGVGMT + R + D A EAI KA+ DAGI + V +G G Sbjct: 8 VVGVGMTKFEKPGRQADVCYPDFAREAITKALQDAGIKYEE---VQQAVAGYVYGDSTCG 64 Query: 63 ALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDAT 122 G+ IP V C++G +A+ + V SG D VL +G EKM S ++ Sbjct: 65 QRAIYEVGMTGIPVYNVNNNCSTGSSALYLAKQIVESGNADCVLALGFEKMERG--SLSS 122 Query: 123 RYLAYASDAEWELFHGVSFVALNALIM---------RHYMNTYGYTEEDLALFAVNAHAN 173 +Y A+ E + + A M + +M YG E A H + Sbjct: 123 KYFDRANPMERHITEMGELAEIGAGPMAAQIFGNAGKEHMKKYGTKPEHFGKIAWKNHKH 182 Query: 174 GAKNPYAMFKRPITVETVMKSPYIADP-LKLFDASPVCDGAAAVIITIPEKAKELGIPKD 232 NPY+ F+ T+E +MKSP + + L P DG+ A I+ + G+ K Sbjct: 183 SVNNPYSQFRDEYTLEQIMKSPQVVEGVLTKLQCCPTSDGSGAAILASEAFVRRHGLEKQ 242 Query: 233 KWVEIAGMGRAIDTINLANREDLLTLKAA---KIAAEKAYKMAKVEPKDIDFFEVHDAFT 289 VEI GM A D + + L+ + ++A ++ + + +P+D+ E+HD F+ Sbjct: 243 A-VEIVGMEMASDPASTFADKSLMKIAGTDMTRLATQRLFAKSGYKPQDVQVVELHDCFS 301 Query: 290 VMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESV 349 ++ EALG+ +G + G G + + GGL ++GHP+GATG+ Q E Sbjct: 302 ANELITYEALGLCGEGNAGEFIDAGDNTYGGKFVVNPSGGLISKGHPLGATGLAQCAELC 361 Query: 350 LQIRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTILR 386 Q+RG A QVP+A++ L N+ G G + V + R Sbjct: 362 WQLRGLAEKR-QVPNAQLALQHNL-GLGGAVVVALYR 396 >sp|Q07598|NLTP_CHICK NONSPECIFIC LIPID-TRANSFER PROTEIN PRECURSOR (NSL-TP) (STEROL CARRIER PROTEIN 2) (SCP-2) (STEROL CARRIER PROTEIN X) (SCP-X) (SCPX) >gi|479569|pir||S34744 sterol carrier protein - chicken >gi|304423|gb|AAA02488.1| (L09231) sterol carrier protein-2 [Gallus gallus] Length = 547 Score = 156 bits (391), Expect = 3e-37 Identities = 121/393 (30%), Positives = 184/393 (46%), Gaps = 21/393 (5%) Query: 6 IVGVGMTPVGEHWRTSLR--DLAVEAILKAMDDAGI--DKVDSLYVGNMASGSFVEQENL 61 +VGVGMT + S+ DLA EA KA+ DAGI V+ VG + S Q Sbjct: 20 VVGVGMTKFAKPSENSVDYPDLAKEAGQKALADAGIPYSAVEQACVGYVYGDSTCGQR-- 77 Query: 62 GALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDA 121 I GL IP + V CA+G A+ + V GL D VL +G E+M + Sbjct: 78 --AIYHGLGLTGIPIINVNNNCATGSTALFMSRQLVEGGLADCVLALGFERMAKGSLASG 135 Query: 122 TRYLAYASDAEWELF---HGVSFVALNALIM----RHYMNTYGYTEEDLALFAVNAHANG 174 D E+ +G++ + + + +M YG E A A H++ Sbjct: 136 FSDRTNPMDKHLEIMINKYGLASAPITPQMFANAGKEHMEKYGTNPEYFAKIAWKNHSHS 195 Query: 175 AKNPYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKW 234 NPY+ F++ T++ V++S + D L + P +GAAA I+ + K + + + Sbjct: 196 TNNPYSQFQKKYTLDEVLQSRKVFDFLTVLQCCPTSNGAAAAILASEDFVKRHKL-QPQA 254 Query: 235 VEIAGMGRAIDTINLANREDLLTLKA---AKIAAEKAYKMAKVEPKDIDFFEVHDAFTVM 291 VEI A D + + + K AAEK +K A ++P D+D E+HD F+V Sbjct: 255 VEILAQVMATDYPSTFEENSCMKMVGYDMTKKAAEKCFKKAGLKPTDVDVIELHDCFSVN 314 Query: 292 AALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQ 351 ++ EALG+ +G+ L G G + I GGL ++GHP+GATG+ Q+ E Q Sbjct: 315 EFITYEALGLCPEGKACDLIDRGDNTYGGKWVINPSGGLISKGHPLGATGLAQSAELCWQ 374 Query: 352 IRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTI 384 +RG A +V A L N+ G G + VT+ Sbjct: 375 LRGLAGRR-EVGGARRALQHNL-GLGGAVVVTL 405 >pir||B40407 sterol carrier protein 2-related form, 58.85K - human Length = 546 Score = 153 bits (383), Expect = 3e-36 Identities = 121/402 (30%), Positives = 187/402 (46%), Gaps = 24/402 (5%) Query: 1 MEKPIIVGVGMT----PVGEHWRTSLRDLAVEAILKAMDDAGI--DKVDSLYVGNMASGS 54 + + +VGVGMT P E+ R DLA EA KA+ DA I VD VG + S Sbjct: 10 LRRVFVVGVGMTKFEKPGAENSR-DYPDLAEEAGKKALADAQIPYSAVDQACVGYVFGDS 68 Query: 55 FVEQENLGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMT 114 Q I G+ IP + V CA+G A+ + + G+ + VL +G EKM+ Sbjct: 69 TCGQR----AIYHSLGMTGIPIINVNNNCATGSTALFMARQLIQGGVAECVLALGFEKMS 124 Query: 115 DAWPSDATRYLAYASDAEWELF---HGVSFVALNALIM----RHYMNTYGYTEEDLALFA 167 +D +L +G+S + + + +M YG E A Sbjct: 125 KGSLGIKFSDRTIPTDKHVDLLINKYGLSAHPVAPQMFGYAGKEHMEKYGTKIEHFAKIG 184 Query: 168 VNAHANGAKNPYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKEL 227 H + NPY+ F+ +++ VM S + D L + P DGAAA I+ ++ Sbjct: 185 WKNHKHSVNNPYSQFQDEYSLDEVMASKEVFDFLTILQCCPTSDGAAAAILASEHLVQKY 244 Query: 228 GIPKDKWVEIAGMGRAIDTINLANREDLLTLKA---AKIAAEKAYKMAKVEPKDIDFFEV 284 G+ + K VEI D + + ++ + +K AA K Y+ + + DI E+ Sbjct: 245 GL-QSKAVEILAQEMMTDLPSSFEEKSIIKMVGFDMSKEAARKCYETSGLGHNDIGLIEL 303 Query: 285 HDAFTVMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQ 344 HD + L+ EALG+ +G+GA L G G++ I GGL ++GHP+GATG+ + Sbjct: 304 HDCCSTNELLTYEALGLCPEGQGATLVDRGDNTYGGNWVINPSGGLISKGHPLGATGLAE 363 Query: 345 TVESVLQIRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTILR 386 E Q+RGEA QVP A++ L N+ G G + VT+ + Sbjct: 364 CAELCWQLRGEAGKR-QVPGAKVALQHNL-GIGGAVVVTLYK 403 >gb|AAF53712.1| (AE003660) CG17597 gene product [Drosophila melanogaster] Length = 378 Score = 152 bits (379), Expect = 9e-36 Identities = 113/394 (28%), Positives = 179/394 (44%), Gaps = 47/394 (11%) Query: 6 IVGVGMTPVGEHWRTS---LRDLAVEAILKAMDDAGI--DKVDSLYVGNMASGSFVEQEN 60 ++GVGMT + R + D A EAI KA+ DAGI ++V G + S Q Sbjct: 8 VIGVGMTKFEKPGRRADACYPDFAKEAITKALQDAGIKFEEVQQAVAGYVYGDSTCGQRA 67 Query: 61 LGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSD 120 + + G+ IP V C++G +A+ + V SG + VL +G EKM Sbjct: 68 IYEV-----GMTGIPVYNVNNNCSTGSSALYLAKQIVESGNSECVLALGFEKMERG---- 118 Query: 121 ATRYLAYASDAEWELFHGVSFVALNALIM----RHYMNTYGYTEEDLALFAVNAHANGAK 176 +L+A I + +M YG E A H + Sbjct: 119 ----------------------SLSAKIFGNAGKEHMKKYGTKPEHFGKIAWKNHKHSVN 156 Query: 177 NPYAMFKRPITVETVMKSPYIADP-LKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWV 235 NPY+ F+ T+E +MKSP + + L P DG+ A I+ + G+ K V Sbjct: 157 NPYSQFRDEYTLEQIMKSPQVVEGVLTKLQCCPTSDGSGAAILASEAFVRRHGLEKQA-V 215 Query: 236 EIAGMGRAIDTINLANREDLLTLKAA---KIAAEKAYKMAKVEPKDIDFFEVHDAFTVMA 292 EI GM A D + + L+ + ++A E+ + + +P+D+ E+HD F+ Sbjct: 216 EIVGMEMASDPASTFADKSLMKIAGTDMTRLATERLFAKSGYKPQDVQVVELHDCFSANE 275 Query: 293 ALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQI 352 ++ EALG+ +G+ + G G + + GGL ++GHP+GATG+ Q E Q+ Sbjct: 276 LITYEALGLCGEGKAGEFIDAGDNTYGGKFVVNPSGGLISKGHPLGATGLAQCAELCWQL 335 Query: 353 RGEAPNGIQVPDAEIGLTQNIGGTGSNITVTILR 386 RG A QVP+A++ L N+ G G + V + R Sbjct: 336 RGLAEKR-QVPNAQLALQHNL-GLGGAVVVALYR 367 >gb|AAK40853.1| Acetyl-CoA c-acetyltransferase (acetoacetyl-CoA thiolase) (acaB-1) [Sulfolobus solfataricus] Length = 359 Score = 150 bits (376), Expect = 2e-35 Identities = 100/345 (28%), Positives = 172/345 (48%), Gaps = 28/345 (8%) Query: 11 MTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVDSLYVGNMASGSFVEQENLGALIADWAG 70 M P+ ++ + DL +EA + ++ +D + V N S + IA+ G Sbjct: 11 MIPIDRYYEYDIYDLVIEAYKNFEGEYDVNSIDLIVVANAYSQKLNNASLIAPKIAEKIG 70 Query: 71 LGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDATRYLAYASD 130 N+P++KV+ A ASGGAA+ + S + + VL+VGVEK +D +PS + Sbjct: 71 KPNVPSIKVDNADASGGAALLTAYSLIKSNMVNSVLIVGVEKQSD-YPSKYLYDAISTNL 129 Query: 131 AEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYAMFKRPITVET 190 ++ ++G+S ++ AL+MR YM YG A +A+ H N +NP+A + + + T Sbjct: 130 DDYMFYNGISSHSVAALLMRQYMKRYGVDRNYFANWAIKMHKNATENPFAYLRFQVDLNT 189 Query: 191 VMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMGRAIDTINLA 250 V+ S I+DP++LFD DGAA ++++ + + I K ++ Sbjct: 190 VINSQIISDPVRLFDVGARADGAAILLLSNNKTESAVKINK--------------ILSAQ 235 Query: 251 NREDLL-TLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALGVAEKGEGAK 309 R D +L + ++ +K ++ E ID +HD++++MAAL LE G+ E G+ Sbjct: 236 ARYDFSPSLPSVRMLRDK-LELKFSERTGID---IHDSYSIMAALMLEEAGIFESGKSLH 291 Query: 310 LAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRG 354 + + GGLKARGH GA+ +YQ E+ +Q+ G Sbjct: 292 NLDSVNVNLG--------GGLKARGHVGGASAIYQLAEAHMQLIG 328 >emb|CAB57766.1| (Y18930) acetyl CoA synthase [Sulfolobus solfataricus] Length = 359 Score = 150 bits (376), Expect = 2e-35 Identities = 100/345 (28%), Positives = 172/345 (48%), Gaps = 28/345 (8%) Query: 11 MTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVDSLYVGNMASGSFVEQENLGALIADWAG 70 M P+ ++ + DL +EA + ++ +D + V N S + IA+ G Sbjct: 11 MIPIDRYYEYDIYDLVIEAYKNFEGEYDVNSIDLIVVANAYSQKLNNASLIAPKIAEKIG 70 Query: 71 LGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDATRYLAYASD 130 N+P++KV+ A ASGGAA+ + S + + VL+VGVEK +D +PS + Sbjct: 71 KPNVPSIKVDNADASGGAALLTAYSLIKSNMVNSVLIVGVEKQSD-YPSKYLYDAISTNL 129 Query: 131 AEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYAMFKRPITVET 190 ++ ++G+S ++ AL+MR YM YG A +A+ H N +NP+A + + + T Sbjct: 130 DDYMFYNGISSHSVAALLMRQYMKRYGVDRNYFANWAIKMHKNATENPFAYLRFQVDLNT 189 Query: 191 VMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMGRAIDTINLA 250 V+ S I+DP++LFD DGAA ++++ + + I K ++ Sbjct: 190 VINSQIISDPVRLFDVGARADGAAILLLSNNKTESAVKINK--------------ILSAQ 235 Query: 251 NREDLL-TLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALGVAEKGEGAK 309 R D +L + ++ +K ++ E ID +HD++++MAAL LE G+ E G+ Sbjct: 236 ARYDFSPSLPSVRMLRDK-LELKFSERTGID---IHDSYSIMAALMLEEAGIFESGKSLH 291 Query: 310 LAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRG 354 + + GGLKARGH GA+ +YQ E+ +Q+ G Sbjct: 292 NLDSVNVNLG--------GGLKARGHVGGASAIYQLAEAHMQLIG 328 >pir||G72467 probable non specific lipid-transfer protein APE2384 - Aeropyrum pernix (strain K1) >gi|5106088|dbj|BAA81399.1| (AP000064) 394aa long hypothetical non specific lipid-transfer protein [Aeropyrum pernix] Length = 394 Score = 148 bits (369), Expect = 1e-34 Identities = 120/358 (33%), Positives = 173/358 (47%), Gaps = 10/358 (2%) Query: 3 KPIIVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGID--KVDSLYVGNMASGSFVEQEN 60 K +VG G+T + R+LA EA +A+D AG+ +D + +G+ A +F Sbjct: 12 KVAVVGAGITLFRRRMLETPRELAWEAARQALDSAGLTLRDIDCVVIGS-APDAFDGVHM 70 Query: 61 LGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSD 120 G +AD +G P V+V +G V SGL VL V EKM+ A P Sbjct: 71 KGEYLADGSGGLFKPTVRVYVGGGTGVFVPIAAWWHVASGLCRTVLAVAEEKMSHARPHP 130 Query: 121 ATRYLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYA 180 + AY D E G + + + AL MR YM+ ++E +AL +V N +P A Sbjct: 131 QGVF-AYIWDPVLERPLGPNLLWIFALEMRRYMHKCNVSKETIALVSVKNKRNALDHPAA 189 Query: 181 MFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGM 240 ITVE V+ S + P+ D SPV DGAAA+++ +A+ + D V I G+ Sbjct: 190 QAAANITVEDVLNSEVLVWPVNRLDVSPVSDGAAALVLASENEARRV---TDSPVWIEGV 246 Query: 241 GRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEP--KDIDFFEVHDAFTVMAALSLEA 298 G +D + NRE L + + AA AYKMA +E +DIDF E +D F +E Sbjct: 247 GWTLDNTHWYNRE-LGYPRYVQYAARMAYKMAGIERPWRDIDFAEPYDPFDYKELHHIEG 305 Query: 299 LGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEA 356 L +A E KL +EG G+ P GGL G+P+ A G+ + E Q+R EA Sbjct: 306 LMLARPCEAPKLLEEGWFDRSGELPTSPSGGLLGVGNPIAAAGLMKAAELFWQLRYEA 363 >gi|11497751 3-ketoacyl-CoA thiolase (acaB-4) [Archaeoglobus fulgidus] >gi|7450482|pir||F69266 3-ketoacyl-CoA thiolase (acaB-4) homolog - Archaeoglobus fulgidus >gi|2650511|gb|AAB91095.1| (AE001097) 3-ketoacyl-CoA thiolase (acaB-4) [Archaeoglobus fulgidus] Length = 398 Score = 145 bits (361), Expect = 1e-33 Identities = 125/375 (33%), Positives = 187/375 (49%), Gaps = 32/375 (8%) Query: 6 IVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVDSLYVGNMASGS--FVEQENLGA 63 I+G ++ + + + E +AM AG+++ D VG + S S F++ G Sbjct: 24 IIGYAVSKLEWDAEKTREEAVFEVTREAMRRAGVERED---VGTVISASTDFLD----GR 76 Query: 64 LIADWAGLGNIPA-VKVEAACASGGA-AVQEGAKAVLSGLEDVVLVVGVEKMTDAW---P 118 I++ +G A +K E+ G A A+ ++SG+ DV L + T +W P Sbjct: 77 TISNCMLIGASGAYLKDESKAEEDGMYAALYAAQRIMSGVHDVALAIS---HTHSWIFNP 133 Query: 119 SDATRYLAYA-SDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKN 177 ++Y+ D + EL +G++ AL A R YM+ G E LA V N AK Sbjct: 134 HQVSQYMLEPWFDRQNELLNGITLAALQA---RLYMSRSGVDEGHLAEVCVKNLRNAAKV 190 Query: 178 PYAMFKRP-ITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVE 236 PYA K +TVE V++S + PL +P CDGAAAV++ E AKEL D+ V Sbjct: 191 PYAFRKMADVTVEEVLESKLYSSPLTELMIAPPCDGAAAVVLASEEVAKEL---CDEPVW 247 Query: 237 IAGMGRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEP--KDIDFFEVHDAFTVMAAL 294 I G+G + D DL L++ ++AAEKAY+MA +E + ID E+ + F + Sbjct: 248 IKGIGNSCD--RYLRDRDLGRLESLRLAAEKAYRMAGIEEPFRQIDVAEISERFAHHELM 305 Query: 295 SLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRG 354 + EALG G G L +EG + GD P+ GG A G + ATG+ + +E+ Q+RG Sbjct: 306 AYEALGFCRDGMGKVLIEEGITEVYGDMPVNPSGGALA-GDAICATGMIRLIEAARQVRG 364 Query: 355 EAPNGIQVPDAEIGL 369 EA N QV D L Sbjct: 365 EAEN--QVEDCRTAL 377 >pir||T27202 hypothetical protein Y57A10C.6 - Caenorhabditis elegans >gi|2190267|dbj|BAA20377.1| (D86473) 3-keto-acyl-CoA thiolase [Caenorhabditis elegans] >gi|3881142|emb|CAA19548.1| (AL023847) contains similarity to Pfam domain: PF00108 (Thiolase), Score=230.7, E-value=6.8e-66, N=1~cDNA EST EMBL:Z14647 comes from this gene~cDNA EST yk168e11.3 comes from this gene~cDNA EST yk168e11.5 comes from this gene~cDNA EST yk146e10.5 comes f> Length = 412 Score = 144 bits (360), Expect = 1e-33 Identities = 111/396 (28%), Positives = 177/396 (44%), Gaps = 24/396 (6%) Query: 3 KPIIVGVGMTPV---GEHWRTSLRDLAVEAILKAMDDAGI--DKVDSLYVGNMASGSFVE 57 K IVGVGMT G D+ EA+ A+DD + + VG + G+ Sbjct: 7 KVYIVGVGMTKFCKPGSVPGWDYPDMVKEAVTTALDDCKMKYSDIQQATVGYLFGGTCCG 66 Query: 58 QENLGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTD-- 115 Q L + GL IP V ACASG + + G + + SG DVVL G E+M Sbjct: 67 QRALYEV-----GLTGIPIFNVNNACASGSSGLFLGKQIIESGNSDVVLCAGFERMAPGS 121 Query: 116 ----AWPSDATRYLAYASDAEWELFHGVSFVALNALIM----RHYMNTYGYTEEDLALFA 167 A P D + +G+ + A + + +M YG E A A Sbjct: 122 LENLAAPIDDRALSVDKHISVMSETYGLEPAPMTAQMFGNAAKEHMEKYGSKREHYAKIA 181 Query: 168 VNAHANGAKNPYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKEL 227 H + NP + F + +++ V+ + I D + L + SP DGAAA ++ + ++ Sbjct: 182 YKNHLHSVHNPKSQFTKEFSLDQVINARKIYDFMGLLECSPTSDGAAAAVLVSEKFLEKN 241 Query: 228 GIPKDKWVEIAGMGRAIDTINLANRED---LLTLKAAKIAAEKAYKMAKVEPKDIDFFEV 284 K + VEI G+ D ++ ++ + A++ + K+ P D+ E+ Sbjct: 242 PRLKAQAVEIVGLKLGTDEPSVFAENSNIKMIGFDMIQKLAKQLWAETKLTPNDVQVIEL 301 Query: 285 HDAFTVMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQ 344 HD F ++ EA+G+ G+G + G + I GGL ++GHP+GATGV Q Sbjct: 302 HDCFAPNELITYEAIGLCPVGQGHHIVDRNDNTYGGKWVINPSGGLISKGHPIGATGVAQ 361 Query: 345 TVESVLQIRGEAPNGIQVPDAEIGLTQNIGGTGSNI 380 VE Q+RG+ QVP+ ++ + NIG G+ + Sbjct: 362 AVELSNQLRGKCGKR-QVPNCKVAMQHNIGIGGAGV 396 >emb|CAA66277.1| (X97685) sterol carrier protein x [Drosophila melanogaster] Length = 543 Score = 141 bits (352), Expect = 1e-32 Identities = 113/397 (28%), Positives = 176/397 (43%), Gaps = 24/397 (6%) Query: 6 IVGVGMTPVGEHWRTS---LRDLAVEAILKAMDDAGIDKVDSLYVGNMASGSFVEQENLG 62 +VGVGMT + R + D A EAI KA+ DAGI + V +G G Sbjct: 8 VVGVGMTKFEKPGRRADVCYPDFAREAITKALQDAGIKYEE---VQQAVAGYVYGDSTCG 64 Query: 63 ALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDAT 122 G+ IP V C++G +A+ + V SG D VL +G EKM S ++ Sbjct: 65 QRAIYEVGMTGIPVYNVNNNCSTGSSALYLAKQIVESGNADCVLALGFEKMERG--SLSS 122 Query: 123 RYLAYASDAEWELFHGVSFVALNALIM---------RHYMNTYGYTEEDLALFAVNAHAN 173 +Y A+ E + + A M + +M YG E A H + Sbjct: 123 KYFDRANPMERHITEMGELAEIGAGPMAAQIFGNAGKEHMKKYGTKPEHFGKIAWKNHKH 182 Query: 174 GAKNPYAMFKRPITVETVMKSPYIADP-LKLFDASPVCDGAAAVIITIPEKAKELGIPKD 232 NPY+ F+ T+E +MKSP + + L P DG+ A I+ + G+ K Sbjct: 183 TVNNPYSQFRDEYTLEQIMKSPQVVEGVLTKLQCCPTSDGSGAAILASEAFVRRNGLEKQ 242 Query: 233 KWVEIAGMGRAIDTINLANREDLLTLKAA---KIAAEKAYKMAKVEPKDIDFFEVHDAFT 289 VEI GM A D + + L+ + ++A E+ + + P+ ++ A Sbjct: 243 A-VEIVGMEMASDPASTFADKSLMKIAGTDMTRLATERLFAKSGTSPRMSRWWNCTIASR 301 Query: 290 VMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESV 349 ++ EALG+ +G+ + G G + + GGL ++GHP+GATG+ Q E Sbjct: 302 ANDLITYEALGLCGEGKAGEFIDAGDNTYGGKFVVNPSGGLISKGHPLGATGLAQCAELC 361 Query: 350 LQIRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTILR 386 Q+RG A QVP+A++ L N+ G G + V + R Sbjct: 362 WQLRGLAEKR-QVPNAQLALQHNL-GLGGAVVVALYR 396 >gi|11497750 3-ketoacyl-CoA thiolase (acaB-3) [Archaeoglobus fulgidus] >gi|7450481|pir||E69266 3-ketoacyl-CoA thiolase (acaB-3) homolog - Archaeoglobus fulgidus >gi|2650512|gb|AAB91096.1| (AE001097) 3-ketoacyl-CoA thiolase (acaB-3) [Archaeoglobus fulgidus] Length = 411 Score = 140 bits (350), Expect = 2e-32 Identities = 118/412 (28%), Positives = 179/412 (42%), Gaps = 33/412 (8%) Query: 1 MEKPIIVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGI--DKVDSLYVGNMASGSFVEQ 58 M + I+G G + G S +L EA+ A++DA I + +++ VGNM + Q Sbjct: 1 MRRVAIIGCGQSKHGRRTDVSQAELVAEAVWAAIEDASIAPEDIEAYAVGNMQGFGGICQ 60 Query: 59 ENLGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWP 118 +L + AD+ G +V GG+ G V SG+ DVVL V EK +D+ Sbjct: 61 PDL--VFADYIAAGGKAMQRVATGGTVGGSTAHLGYYEVASGMYDVVLAVSWEKHSDSAE 118 Query: 119 SDATRYLAYASDAEWELFHGVSF--------------VALNALIMRHYMNTYGYTEEDLA 164 AT L + + A + ++A YM G + E Sbjct: 119 PGATTGLLHVAFANLSYMMKIGMDMRSFAIMGLAGAAAGISAYQAAFYMARSGCSIEHFD 178 Query: 165 LFAVNAHANGAKNPYAMFKRP-ITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEK 223 + A A N AKN YA K P T E + K+ + P++ P DGA+ VI + Sbjct: 179 MVAAKARRNAAKNKYAHLKWPNCTPEDIAKTEMLIWPMRFGHVCPASDGASCVIYASEDA 238 Query: 224 AKELGIPKDKWV--------EIAGMGRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVE 275 K LGI + WV E A G + + + D A ++A KAY+ A ++ Sbjct: 239 VKRLGIKEVAWVKGVAAYADEEADQGESYQGTAVVDYSDQT---GAILSARKAYERAGIK 295 Query: 276 P--KDIDFFEVHDAFTVMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKAR 333 K+ID E++ F + E LG + G K +EG IDGD+PI GG+ A Sbjct: 296 DPRKEIDVAEIYAPFPHQELMFSERLGFFDDGTAWKAVEEGVTEIDGDFPICPSGGVNAT 355 Query: 334 GHPVGATGVYQTVESVLQIRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTIL 385 + +G++G+ + VE+ LQI G+A D + GG TV +L Sbjct: 356 -NAIGSSGMQRVVEAALQIMGKAEEHQVPKDVRNAVAHAWGGQVQFNTVMVL 406 >emb|CAA64718.1| (X95443) sterol carrier protein x-related thiolase [Drosophila melanogaster] Length = 414 Score = 138 bits (343), Expect = 1e-31 Identities = 112/397 (28%), Positives = 175/397 (43%), Gaps = 24/397 (6%) Query: 6 IVGVGMTPVGEHWRTS---LRDLAVEAILKAMDDAGIDKVDSLYVGNMASGSFVEQENLG 62 +VGVGMT + R + D A EAI KA+ DAGI + V +G G Sbjct: 8 VVGVGMTKFEKPGRRADVCYPDFAREAITKALQDAGIKYEE---VQQAVAGYVYGDSTCG 64 Query: 63 ALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDAT 122 G+ IP V C++G +A+ + V SG D VL +G EKM S ++ Sbjct: 65 QRAIYEVGMTGIPVYNVNNNCSTGSSALYLAKQIVESGNADCVLALGFEKMERG--SLSS 122 Query: 123 RYLAYASDAEWELFHGVSFVALNALIM---------RHYMNTYGYTEEDLALFAVNAHAN 173 +Y A+ E + + A M + +M YG E A H + Sbjct: 123 KYFDRANPMERHITEMGELAEIGAGPMAAQIFGNAGKEHMKKYGTKPEHFGKIAWKNHKH 182 Query: 174 GAKNPYAMFKRPITVETVMKSPYIADP-LKLFDASPVCDGAAAVIITIPEKAKELGIPKD 232 N Y+ F+ T+E +MKSP + + L P DG+ A I+ + G+ K Sbjct: 183 TVNNRYSQFRDEYTLEQIMKSPQVVEGVLTKLQCCPTSDGSGAAILASEAFVRRNGLEKQ 242 Query: 233 KWVEIAGMGRAIDTINLANREDLLTLKAA---KIAAEKAYKMAKVEPKDIDFFEVHDAFT 289 VEI GM A D + + L+ + ++A E+ + + P+ ++ A Sbjct: 243 A-VEIVGMEMASDPASTFADKSLMKIAGTDMTRLATERLFAKSGTSPRMSRWWNCTIASR 301 Query: 290 VMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESV 349 ++ EALG+ +G+ + G G + + GGL ++GHP+GATG+ Q E Sbjct: 302 ANDLITYEALGLCGEGKAGEFIDAGDNTYGGKFVVNPSGGLISKGHPLGATGLAQCAELC 361 Query: 350 LQIRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTILR 386 Q+RG A QVP+A++ L N+ G G + V + R Sbjct: 362 WQLRGLAEKR-QVPNAQLALQHNL-GLGGAVVVALYR 396 >pir||E70676 probable nonspecific lipid-transfer protein Rv3540c - Mycobacterium tuberculosis (strain H37RV) >gi|1666120|emb|CAB05038.1| (Z82098) ltp2 [Mycobacterium tuberculosis] Length = 386 Score = 135 bits (336), Expect = 1e-30 Identities = 110/366 (30%), Positives = 167/366 (45%), Gaps = 20/366 (5%) Query: 6 IVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVDSLYVGNMASGSFVEQENLGALI 65 IVG+G T ++ S LA EA+L A+ DAG+ D V + + F N + Sbjct: 8 IVGIGATDFSKNSGRSELRLAAEAVLDALADAGLSPTD---VDGLTT--FTMDTNTEIAV 62 Query: 66 ADWAGLGNIPAV-KVEAACASGGAAVQEGAKAVLSGLEDVVLVVGV--EKMTDAWPSDAT 122 A AG+G + K+ + A VQ A AV +G+ DVV+ E+ + T Sbjct: 63 ARAAGIGELTFFSKIHYGGGAACATVQHAAMAVATGVADVVVAYRAFNERSGMRFGQVQT 122 Query: 123 RYLAYAS----DAEWELFHGVSFVALN-ALIMRHYMNTYGYTEEDLALFAVNAHANGAKN 177 R A D + HG+S A A+I R YM+ G T D +V + A N Sbjct: 123 RLTENADSTGVDNSFSYPHGLSTPAAQVAMIARRYMHLSGATSRDFGAVSVADRKHAANN 182 Query: 178 PYAMFK-RPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVE 236 P A F +PIT+E S +IA+PL+L D DGA A+++T +A++L + +E Sbjct: 183 PKAYFYGKPITIEDHQNSRWIAEPLRLLDCCQETDGAVAIVVTSAARARDLK-QRPVVIE 241 Query: 237 IAGMGRAIDTINLAN--REDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAAL 294 A G + D + + R +L L + + + + + P D+ ++D FT + Sbjct: 242 AAAQGCSPDQYTMVSYYRPELDGLPEMGLVGRQLWAQSGLTPADVQTAVLYDHFTPFTLI 301 Query: 295 SLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRG 354 LE LG KGE +G I + G PI T GG + G G+ E V Q+RG Sbjct: 302 QLEELGFCGKGEAKDFIADGAIEVGGRLPINTHGGQLGEAYIHGMNGI---AEGVRQLRG 358 Query: 355 EAPNGI 360 + N + Sbjct: 359 TSVNPV 364 >pir||A83518 hypothetical protein PA1016 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9946927|gb|AAG04405.1|AE004534_3 (AE004534) hypothetical protein [Pseudomonas aeruginosa] Length = 383 Score = 132 bits (329), Expect = 6e-30 Identities = 115/395 (29%), Positives = 183/395 (46%), Gaps = 37/395 (9%) Query: 3 KPIIVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGI--DKVDSLYVGNMASG----SFV 56 K IVG+G VGE S +L +A LKA+ DAG+ +D+++ + S Sbjct: 8 KTAIVGIGSAGVGEAPGYSAIELLGQASLKAIADAGLKLSDIDAIFAATSSHAFPTLSVA 67 Query: 57 EQENLGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVV-GVEKMTD 115 E + D +G +S + + A+ +GL D L+ G + T Sbjct: 68 EYLGIRPKFVDGTNIGG----------SSFELHLLQATLALEAGLCDAALICYGSNQRT- 116 Query: 116 AWPSDATRYLAYASDAEWELFHGVSF-----VALNALIMRHYMNTYGYTEEDLALFAVNA 170 A L S+ +W H + + AL +M+ YG T E LA AV+A Sbjct: 117 -----AGGRLVSMSEPQW---HETPYKPRHPITAYALAASRHMHQYGTTREQLAEVAVSA 168 Query: 171 HANGAKNPYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIP 230 NP A + P++V+ V+ + ++DPL D V DG A ++ E+A++L Sbjct: 169 RQWANLNPEAFARGPLSVDDVLAARMVSDPLSAADCCLVTDGGGACVVVRAERARDLPNA 228 Query: 231 KDKWVEIAGMGRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTV 290 ++ AG +++ + LT+ AA +A +A +MA V DID ++DAFT+ Sbjct: 229 PVYFLGAAGAQWHRSIVSMPD----LTVTAASESAPRAMQMAGVRHADIDLVMLYDAFTI 284 Query: 291 MAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVL 350 L LE LG KGEG + G+IA G+ + T GG + HP G G++ +E+V Sbjct: 285 NTLLFLEDLGFCAKGEGGPFVQGGRIAPGGELAVNTNGGGLSCVHP-GMYGMFLIIEAVT 343 Query: 351 QIRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTIL 385 Q+R +A Q+ A++ L GGT S+ +L Sbjct: 344 QLRRQAGER-QLAKADVALLHGNGGTLSSQVTALL 377 >pir||D70674 probable lipid carrier protein - Mycobacterium tuberculosis (strain H37RV) >gi|1666137|emb|CAB05053.1| (Z82098) hypothetical protein Rv3523 [Mycobacterium tuberculosis] Length = 394 Score = 125 bits (311), Expect = 8e-28 Identities = 116/385 (30%), Positives = 178/385 (46%), Gaps = 33/385 (8%) Query: 6 IVGVGMTP-VGEHWRTSLRDLAVEAILKAMDDAG--IDKVDSLYVGNMASGSFVEQENLG 62 ++G G T V + S+ L EAI +A+ D+G D +D++ VG + F E + Sbjct: 8 VLGTGQTKYVAKRQDVSMNGLVREAIDRALADSGSTFDDIDAVVVGK--APDFFEGVMMP 65 Query: 63 AL-IADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDA 121 L +AD G P ++V A + GG+ A V SG VL + EK ++ Sbjct: 66 ELFMADAMGATGKPLIRVHTAGSVGGSTGVVAASLVQSGKYRRVLALAWEKQSE------ 119 Query: 122 TRYLAYASDAEWELFHGVSFV--------ALNALIMRHYMNTYGYTEEDLALFAVNAHAN 173 S+A W L V F A +R Y+ G A+ AV N Sbjct: 120 -------SNAMWALSIPVPFTKPVGAGAGGYFAPHVRAYIRRSGAPAHIGAMVAVKDRLN 172 Query: 174 GAKNPYAMFKRP-ITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKD 232 G++NP A ++P IT+E VM S + DP++ + P DGA AV++ E A Sbjct: 173 GSRNPLAHLQQPDITLEKVMASQMLWDPIRFDETCPSSDGACAVVVGDEEIADARLAQGH 232 Query: 233 KWVEIAGMGRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPK--DIDFFEVHDAFTV 290 I G + + A R D + +A + AA +K A + +ID E++ F+ Sbjct: 233 PVAWIHGTALRTEPLAFAGR-DQVNPQAGRDAAAALWKAAGITSPIDEIDAAEIYVPFSW 291 Query: 291 MAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVL 350 + LE LG A +GEG KL + G+ AI G P+ GG+ + +P+GA+G+ + E+ + Sbjct: 292 FEPMWLENLGFAREGEGWKLTEAGETAIGGRLPVNPSGGVLS-ANPIGASGLIRFAEAAI 350 Query: 351 QIRGEAPNGIQVPDAEIGLTQNIGG 375 Q+ G+A QVP A L GG Sbjct: 351 QVMGKA-EARQVPGARKALGHAYGG 374 >gb|AAB48108.1| (U41818) PhlC [Pseudomonas fluorescens] Length = 398 Score = 125 bits (311), Expect = 8e-28 Identities = 112/407 (27%), Positives = 173/407 (41%), Gaps = 62/407 (15%) Query: 13 PVGEHWRTSLRDLAVEAILKAMDDAGIDKVDSLYVGNMASGSFV-EQENLGALIADWAGL 71 P R + +++ VE+ +A++ + + V G + E LG I+D G+ Sbjct: 17 PGSSRVRQTFKEMIVESAYQALNAIKMHPRELQAVAYGYHGEGISEYGGLGPTISDALGI 76 Query: 72 GNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDATRYLAYASDA 131 P A C S + Q + V SG D+VL G EKMTD + + Y+ +++ Sbjct: 77 SPAPTFMSTANCTSSSVSFQMAHQMVASGEYDIVLCGGFEKMTDHF--NYAEYIGSSTEC 134 Query: 132 EWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFA-------VNAHANGAKNPYAMFKR 184 E++ F G+S AL Y +GY + + A + AH Y + Sbjct: 135 EYDYFLGISHTDAFALATAEYFEKFGYAGREADVLATFGRQMRIYAHNTPTATRYGV--- 191 Query: 185 PI-TVETVMKSPYIADPLKLFDASP----VCDGAAAVIITIP------------------ 221 P+ ++ET+ S L +AS V + A T P Sbjct: 192 PVPSLETLKNSEACGSMLAWGEASGCAILVAEHLAHRYTTQPVFVRGCAYTGVSHYFGTR 251 Query: 222 ---EKAKELGIPKDKWVEIAGMGRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKD 278 K G+PKD +G A+ ++A AE AYK A + KD Sbjct: 252 YHNPTLKYPGLPKD-------VGMAVSANSIA-------------CAEIAYKKAGITAKD 291 Query: 279 IDFFEVHDAFTVMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVG 338 ID +V+D + +E++GV G+ EG IA+DG P+ T GG RGH G Sbjct: 292 IDVAQVYDLLGA-GLIQMESMGVCGPGQAGDFVLEGGIALDGQLPLNTDGGNIGRGHASG 350 Query: 339 ATGVYQTVESVLQIRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTIL 385 G+ E Q+RGE+ N QV DA IG++QN+GG ++ +V +L Sbjct: 351 CDGILHITELFRQLRGESNN--QVKDARIGVSQNLGGYAAHNSVIVL 395 >pir||B70582 probable lipid-transfer protein - Mycobacterium tuberculosis (strain H37RV) >gi|2078063|emb|CAB08512.1| (Z95210) hypothetical protein Rv0914c [Mycobacterium tuberculosis] Length = 412 Score = 123 bits (306), Expect = 3e-27 Identities = 112/376 (29%), Positives = 164/376 (42%), Gaps = 29/376 (7%) Query: 24 DLAVEAILKAMDDAGIDKVDS-----LYVGNMASGSFVEQENLGALIADWAG-LGNIPAV 77 DL E + + A +D D ++V N F Q +LGA+ A L + PA Sbjct: 28 DLTREVVDGTLTAAKVDAADLAAAGVVHVANAFGEMFARQGHLGAMPATVCDDLWDTPAT 87 Query: 78 KVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDATRYLAYASDAEWELFH 137 + EAACASG A + SG V LVVG+E + P D + S A W Sbjct: 88 RHEAACASGSVATLAAMADLRSGAYRVALVVGLE-LEKTVPGDTAA--EHLSAAAWTGHE 144 Query: 138 GVS----FVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYAMFKR-----PITV 188 G + ++ A + Y YG + L A AN +NP A + PIT Sbjct: 145 GAEARYLWPSMFAQVADEYDRRYGLDDTHLRAIAQLNFANARRNPNAQTRGWTIPDPITD 204 Query: 189 ETVMKSPYIADPLKLFDASPVCDGAAAVIITIP------EKAKELGIPKDKWVEIAGMG- 241 + +P L+ FD S + DG A +++ A+ +G G+G Sbjct: 205 DDAT-NPLTEGRLRRFDCSQMTDGGAGLVLVSDAYLRDHRDARPIGRIDGWGHRTVGLGL 263 Query: 242 -RAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALG 300 + +D + + L L + A + A+V D+D EVHD FT L+++ +G Sbjct: 264 RQKLDRVAQGDSAPYL-LPHVRATVLDALRRARVTLDDLDGIEVHDCFTPSEYLAIDHIG 322 Query: 301 VAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGI 360 + GE K + G+I I G PI GGL GHPVGA+GV +++ Q+ G A Sbjct: 323 LTGPGESWKAIENGEIEIGGRLPINPSGGLIGGGHPVGASGVRMLLDAAKQVSGIA-GDY 381 Query: 361 QVPDAEIGLTQNIGGT 376 QV +AE T N GG+ Sbjct: 382 QVENAEAFGTLNFGGS 397 >gi|11498573 3-ketoacyl-CoA thiolase (acaB-10) [Archaeoglobus fulgidus] >gi|7450470|pir||H69370 3-ketoacyl-CoA thiolase (acaB-10) homolog - Archaeoglobus fulgidus >gi|2649632|gb|AAB90275.1| (AE001038) 3-ketoacyl-CoA thiolase (acaB-10) [Archaeoglobus fulgidus] Length = 388 Score = 123 bits (305), Expect = 4e-27 Identities = 115/366 (31%), Positives = 170/366 (46%), Gaps = 37/366 (10%) Query: 21 SLRDLAVEAILKAMDDAGIDK---VDS-------LYVGNMASGSFVEQENLGALIADWAG 70 S +++ EA ++A DAGI+ VDS +Y G FV + LGA++ Sbjct: 28 SWKEIMYEAAVRAYTDAGINPRRDVDSFVTCAEDIYEGFAIFDEFVPDQ-LGAVVK---- 82 Query: 71 LGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDATRYLAYASD 130 P V A G A + SGL D+ +V K +D + +A D Sbjct: 83 ----PTCTVTADFLYGVATAY---MHINSGLADIAVVEAHSKASDI--QTFGNVVKFAMD 133 Query: 131 AEWELFHGVSF-VALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYAMFKRPITVE 189 W G + L AL M YM +EED+A V N NP A + +T++ Sbjct: 134 PIWLRNVGNAHPYYLAALEMFQYMAERCLSEEDVARVVVKNKNNALLNPAAPYAANVTLD 193 Query: 190 TVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMGRAIDTI-- 247 VM SP + DP+K + +P+ DG ++ E A++L D V + G+G +T Sbjct: 194 DVMASPKLFDPMKKMEIAPLADGCVVFVLASDEVARKL---TDNPVWVKGIGWWSETYGY 250 Query: 248 NLANREDLLTLKAAKIAAEKAYKMAKVE--PKDIDFFEVHDAFTVMAALSLEALGVAEKG 305 + A+ + KAAK+A YKMA + K++DF EV D F +EAL +A K Sbjct: 251 DTASFSAMYAYKAAKMA----YKMAGIANPAKEVDFAEVDDRFAFKEMQHIEALQLAGKF 306 Query: 306 EGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGIQVPDA 365 + A+L EG DG P+ GG G+ + TG + +E VLQ+RGEA Q+ D Sbjct: 307 DVARLMAEGYFDRDGAKPVNVSGGSLGVGNLLECTGGQKALEVVLQLRGEAGKR-QLSDV 365 Query: 366 EIGLTQ 371 E+G+ Q Sbjct: 366 EVGVAQ 371 >pir||T50937 DitF protein [imported] - Pseudomonas abietaniphila >gi|4455077|gb|AAD21068.1| (AF119621) DitF [Pseudomonas abietaniphila] Length = 397 Score = 113 bits (281), Expect = 3e-24 Identities = 104/395 (26%), Positives = 173/395 (43%), Gaps = 35/395 (8%) Query: 6 IVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVD----SLYVGNMASGSFVEQENL 61 I G+G + VG S L +EA L+A+ DAG+ + D + + G+ +G Sbjct: 13 ITGIGQSEVGRPSSKSAMRLTLEACLEAIADAGLTREDIDGVACWPGDNNNGDPFSPVGP 72 Query: 62 GALIA------DWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTD 115 AL + +W G G + A V GA A+ +GL VLV Sbjct: 73 SALKSALGLNVNWFGAGYEGPGPL--------AGVINGAMAIAAGLCRHVLVFRTITEAS 124 Query: 116 AWPSD------ATRYLAYASDAEWELFHGV---SFVALNALIMRHYMNTYGYTEEDLALF 166 A + + + S W+ F S + L AL + + + YG E LA Sbjct: 125 ARQHNKQAGALSAKTQGRDSSHAWQWFTPFNVHSGINLMALYAQRHFHEYGTRPEQLAQI 184 Query: 167 AVNAHANGAKNPYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKE 226 A+ AN +NP A+++ P+T++ M S I+ PL++FD CD + A++++ + AK+ Sbjct: 185 ALTCRANAQRNPKAIYRTPMTMDDYMASRMISSPLRMFDCDVHCDASTAIVLSRRDVAKD 244 Query: 227 LGIPKDKWVEIAGMGRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHD 286 + + + I MG A+D + + LT AA + P D+ +++D Sbjct: 245 ---TRHQPIRIEAMGAALDQ-PWSWDQISLTQMAAFDVGRMMWARTDYTPSDVGSAQLYD 300 Query: 287 AFTVMAALSLEALGVAEKGEGAKLAKEGQ-IAIDGDYPIQTMGGLKARGHPVGATGVYQT 345 F+++ + LEALG+ G+ + G+ IA+ G PI T GG + G G V+ Sbjct: 301 GFSILTMIWLEALGLCSTGQSGAFVEGGERIALTGQLPINTNGGQLSGGRTHGLGYVH-- 358 Query: 346 VESVLQIRGEAPNGIQVPDAEIGLTQNIGGTGSNI 380 E+ LQ+ G A P + G G ++ Sbjct: 359 -EACLQLWGRAEGRQTRPHTVAAVAAGGGPLGGSL 392 >gb|AAK42245.1| Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) (acaB-2) [Sulfolobus solfataricus] Length = 381 Score = 107 bits (264), Expect = 3e-22 Identities = 104/355 (29%), Positives = 159/355 (44%), Gaps = 42/355 (11%) Query: 21 SLRDLAVEAILKAMDDAG-----------IDKVDSLYVGNMASGSFVEQENLGALIADWA 69 S R++ EA +A DAG I + + G + F + GA+ Sbjct: 26 SFREMVFEAASRAYKDAGGINPRSDVDSFISCQEDFWEGISIADEFAPDQMGGAMR---- 81 Query: 70 GLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWP-SDATRYLA-- 126 P + V G A A + SG+ +VV + K++D SD ++ Sbjct: 82 -----PTMTVAGDSLQGLA---HAAMHINSGVANVVSIEAHSKVSDILTFSDLEKFAMDP 133 Query: 127 -YASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYAMFKRP 185 Y FH ++ L+A+ +M+ G T EDLAL G +P A F Sbjct: 134 IYIRSINPPNFHFIA--GLDAV---KFMHRKGITREDLALVVEKNKKAGLSSPRASFASN 188 Query: 186 ITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMGRAID 245 I+ VMK Y+ PL D +P DGA +++ E AK+L KD ++ + G+G A D Sbjct: 189 ISAVDVMKKNYVVYPLSELDIAPFVDGAIVIVVADEEVAKKL--KKDDYLVVKGIGFATD 246 Query: 246 TINLANREDLLTLKAAKIAAEKAYKMAKVEP--KDIDFFEVHDAFTVMAALSLEALGVAE 303 + NL E L KIA++ AYKMA VE + D V D ++ LE L V+E Sbjct: 247 SSNLETAE-LGKANYMKIASDMAYKMAGVETPRRYFDAVFVDDRYSYKELQHLEGLRVSE 305 Query: 304 KGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATG---VYQTVESVLQIRGE 355 E +K +EG + G+ P+ +GG A+G P+ A+G + +E + Q +GE Sbjct: 306 --EPSKDLREGNFSPQGEVPVNPLGGHMAKGVPLEASGFSLLLDAIEYIKQGKGE 358 >gb|AAK43216.1| Acetyl-CoA c-acetyltransferase (acetoacetyl-CoA thiolase) (acaB-10) [Sulfolobus solfataricus] Length = 385 Score = 106 bits (263), Expect = 3e-22 Identities = 93/375 (24%), Positives = 168/375 (44%), Gaps = 26/375 (6%) Query: 24 DLAVEAILKAMDDAGIDK--VDSLYVGNMAS--GSFVEQENLGALIADWAGLGNIPAVKV 79 +L + + A++ AG+DK VD +Y+ + + +A + G+ Sbjct: 19 ELLADTVFSALEMAGLDKNYVDGIYLTYLPGTFDGYANSHFFTNQVAQYLGIRPKFTQIF 78 Query: 80 EAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDAT------RYLAYASDAEW 133 + AS + + KA+ +G + +L + K T+ T Y + Sbjct: 79 DYGGASALSMIHRAYKAIKAGEGETILCIVGGKATELRNKGVTVDAIDKAYPNVSLTPFD 138 Query: 134 ELFHGVSF---VALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYAMFKRPITVET 190 LF G++ V+ AL+ + + T+E AL AV N +N AMFK P+T+E Sbjct: 139 RLFRGLNDLNPVSDYALVANRHKYLFKSTDEQRALIAVRQRFNAMQNSKAMFKDPLTIEQ 198 Query: 191 VMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMGRAIDTINLA 250 V+KSP ++ PL L + DG +++ +++ + + ++I G G A Sbjct: 199 VLKSPLVSYPLHLLEIVYPIDGFHVFVVS--KRSSKSALTN---IDILGYGEAHWPFMPT 253 Query: 251 NREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALGVAEKGEGAKL 310 ++++ A + + K + ID FE++D+FT+ L +E +G+AEKG+G Sbjct: 254 ELDEIVYTPA--VESSKGLLNGR-----IDAFELYDSFTITVMLQVEDIGLAEKGKGGSF 306 Query: 311 AKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGIQVPDAEIGLT 370 + GD PI T GG G P +G E++LQ+ A +G QV ++ Sbjct: 307 FENHDTTFKGDVPINTGGGSLNTGQPAYMSGGVILEEALLQLNDMA-DGHQVKGTDVVFL 365 Query: 371 QNIGGTGSNITVTIL 385 IGG + +V+++ Sbjct: 366 NGIGGWNRSHSVSLV 380 >gb|AAK42641.1| Acetyl-CoA c-acetyltransferase (acetoacetyl-CoA thiolase) (acaB-6) [Sulfolobus solfataricus] Length = 380 Score = 106 bits (262), Expect = 5e-22 Identities = 92/368 (25%), Positives = 168/368 (45%), Gaps = 17/368 (4%) Query: 24 DLAVEAILKAMDDAGIDKVD-SLYVGNMASGSFVEQE---NLGALIADWAGLGNIPAVKV 79 +L E +A+D AG++ D + N+ GSF N A I+++ G+ V Sbjct: 19 ELLKEVTDEALDIAGLNYADVDGIMANIGRGSFHGNRTYLNPPAQISEYFGIKPKIIEHV 78 Query: 80 EAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPS--DATRYLAYASDAEWELFH 137 + S + + KA+ +G + +L + K++ + T + D +++ Sbjct: 79 QYGGPSVLSMIYRAYKAIKAGDAETILCIQGGKISHLRDNHFQKTDIIDSPFDEYIKIYD 138 Query: 138 GVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYAMFKRPITVETVMKSPYI 197 +S ++ A++ + +G T+E A AV N + NP A+F+ PITVE V+KS + Sbjct: 139 QMSPISDYAMVAYRHSKLFGTTDEQRARIAVIQRYNASYNPKALFRNPITVEDVLKSRIV 198 Query: 198 ADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMGRAIDTINLANREDLLT 257 + PL L + DG +++ L + ++I G A A +D++ Sbjct: 199 SYPLHLLEIVYPIDGFHVFVVSKRSSKSAL-----RNIDILAYGEAHWPNPPAEWDDIIY 253 Query: 258 LKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALGVAEKGEGAKLAKEGQIA 317 + A ++ + +V D F+++D+FT+ L +E +G+ EKG+ + + ++ Sbjct: 254 TPTTESAKRASFDLNRV-----DAFQLYDSFTITVMLQMEDIGLVEKGKVGQFVESHDLS 308 Query: 318 IDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGIQVPDAEIGLTQNIGGTG 377 GD PI T GG G P +G E++LQ+ A NG QV A + IG Sbjct: 309 FKGDVPINTGGGSLNTGQPAYMSGGVILEEALLQLNDMA-NGHQVKGANVIFLNGIGWWS 367 Query: 378 SNITVTIL 385 +VT++ Sbjct: 368 RRHSVTLV 375 >gi|4506823 sterol carrier protein 2 [Homo sapiens] >gi|432977|gb|AAA03558.1| (M75884) sterol carrier protein-2 [Homo sapiens] Length = 289 Score = 97.1 bits (238), Expect = 3e-19 Identities = 52/126 (41%), Positives = 74/126 (58%), Gaps = 2/126 (1%) Query: 261 AKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALGVAEKGEGAKLAKEGQIAIDG 320 +K AA K Y+ + + P DID E+HD F+ L+ EALG+ +G+GA L G G Sbjct: 23 SKEAARKCYEKSGLTPNDIDVIELHDCFSTNELLTYEALGLCPEGQGATLVDRGDNTYGG 82 Query: 321 DYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGIQVPDAEIGLTQNIGGTGSNI 380 + I GGL ++GHP+GATG+ Q E Q+RGEA QVP A++ L N+ G G + Sbjct: 83 KWVINPSGGLISKGHPLGATGLAQCAELCWQLRGEAGKR-QVPGAKVALQHNL-GIGGAV 140 Query: 381 TVTILR 386 VT+ + Sbjct: 141 VVTLYK 146 >gb|AAA42120.1| (M34728) sterol carrier protein-2 (SCP-2) [Rattus norvegicus] Length = 273 Score = 94.4 bits (231), Expect = 2e-18 Identities = 51/126 (40%), Positives = 72/126 (56%), Gaps = 2/126 (1%) Query: 261 AKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALGVAEKGEGAKLAKEGQIAIDG 320 +K AA K Y+ + + P D+D E+HD F+ L+ EALG+ +G+G L G G Sbjct: 7 SKEAARKCYEKSGLGPSDVDVIELHDCFSTNELLTYEALGLCPEGQGGALVDRGDNTYGG 66 Query: 321 DYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGIQVPDAEIGLTQNIGGTGSNI 380 + I GGL ++GHP+GATG+ Q E Q+RGEA QVP A++ L N+ G G Sbjct: 67 KWVINPSGGLISKGHPLGATGLAQCAELCWQLRGEAGKR-QVPGAKVALQHNL-GLGGAA 124 Query: 381 TVTILR 386 VT+ R Sbjct: 125 VVTLYR 130 >gi|11497817 3-ketoacyl-CoA thiolase (acaB-5) [Archaeoglobus fulgidus] >gi|7450483|pir||A69275 3-ketoacyl-CoA thiolase (acaB-5) homolog - Archaeoglobus fulgidus >gi|2650441|gb|AAB91030.1| (AE001092) 3-ketoacyl-CoA thiolase (acaB-5) [Archaeoglobus fulgidus] Length = 368 Score = 93.2 bits (228), Expect = 4e-18 Identities = 104/396 (26%), Positives = 162/396 (40%), Gaps = 63/396 (15%) Query: 6 IVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDK--VDSLYVGNMASGSFVEQENLGA 63 IVGVG + H ++A A +A++DAGI++ VDS +G Sbjct: 18 IVGVGFSEFRIH-EEPFYNVAFLAAKRALEDAGIERGEVDSFILGGY------------- 63 Query: 64 LIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDATR 123 D G+G + A A GA ++ + +D + + + M S+ T Sbjct: 64 ---DNLGVGRTISNMYTAPAA--GAYLRHEIRVS----DDALFALPLAFMKVKSGSEITM 114 Query: 124 YLAYASDAEWEL-----------FH---GVSFVALNALIMRHYMNTYGYTEEDLALFAVN 169 LA+ +E + FH +S A+ Y YG EE +A V Sbjct: 115 LLAFGHSSETPIELVELQSLDPFFHRPFNLSLPVFFAMQSYAYRERYGVKEEKIAEVVVR 174 Query: 170 AHANGAKNPYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGI 229 GAKNP A + ++VE V+ S ++ PL+ + + CDG A I+ A+ L Sbjct: 175 MREKGAKNPRAYIREKVSVEDVLSSEVVSSPLRRLEMAEWCDGCVAFILAEETVARRL-- 232 Query: 230 PKDKWVEIAGMGRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFT 289 D V ++G+G + + N L L +AE A+KM+ E KD++ E+ D Sbjct: 233 -SDSPVWVSGLGWSAE--NYYFDRSLHDLPFVAKSAEMAFKMSGKERKDVEALEISDLTA 289 Query: 290 VMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESV 349 + LEALG AE G G + G + G G L + G+TG + V Sbjct: 290 DYYCMILEALGFAETGRGWEF--NGDVNFSG-------GALCTNAY--GSTGAFLLASIV 338 Query: 350 LQIRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTIL 385 +IR + E G+ Q++ G V IL Sbjct: 339 ERIR--------KGEIECGMAQSMSGYAQKSCVAIL 366 >emb|CAC00412.1| (AL160371) possible thiolase [Leishmania major] Length = 393 Score = 89.3 bits (218), Expect = 7e-17 Identities = 103/401 (25%), Positives = 167/401 (40%), Gaps = 39/401 (9%) Query: 12 TPVGEHWRTSLRDLAVEAILKAMDDAGIDKVDS---LYVGNMASGSFVEQENLGALIADW 68 T +G R+S+ DLA EA+ +A +A I D + +++SG F++ L Sbjct: 1 TAIGALKRSSI-DLAREAMERAFAEANIAAKDVGALIATPSLSSGHFMQAHYLATQFQLT 59 Query: 69 AGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDATRYLAYA 128 A PA+ + G + + A+ L V V +DA + + A Sbjct: 60 AAN---PAMLFKTVDTGGASPISSIGAALDFFRRMPGLNVAVVVSSDAVHTLPSSEFAKR 116 Query: 129 SD--------AEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYA 180 S+ AE + HG F A + M YG E LA+ V A ++P A Sbjct: 117 SNESVPSPYLAEPHIPHGYDFYA------QWQMKRYGLKREQLAMVPVLMSAMSVRHPDA 170 Query: 181 MFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKE---LGIPKDKWVEI 237 M +R ++E V+ + IA L + + DGA A+++ E K+ G + + Sbjct: 171 MCRRRYSLEEVLGARQIAPVTNLPECARRADGAVAIVLAREEHYKQHLATGPLDGRRPYV 230 Query: 238 AGMGRAIDTINLANREDLLTLKAAKIAAEKAYKMAK-----VEPKDIDFFEVHDAFTVMA 292 G+G A + + +T + + +A ++A + DIDFF ++D F + Sbjct: 231 LGVGEASGPLYPPATHEEVTPET--FSCHRAMRLAYEATGGLSTSDIDFFGLYDCFPICF 288 Query: 293 ALSLEALGVAEKGEGAKLAKE--------GQIAIDGDYPIQTMGGLKARGHPVGATGVYQ 344 +LEA G+ +GEG ++ +E G ++PI T GGL G P +Y Sbjct: 289 IRALEAAGLCREGEGGQMVEEAYRRAVQHGGDVDPSEFPINTHGGLMCFGAPWEVPAMYN 348 Query: 345 TVESVLQIRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTIL 385 E+V Q+ G+A P L GG S V IL Sbjct: 349 VAEAVAQLGGQAGPRQVHPTPRRALVYGNGGIFSASAVAIL 389 >pir||E72467 probable non specific lipid-transfer protein APE2382 - Aeropyrum pernix (strain K1) >gi|5106086|dbj|BAA81397.1| (AP000064) 360aa long hypothetical non specific lipid-transfer protein [Aeropyrum pernix] Length = 360 Score = 81.5 bits (198), Expect = 1e-14 Identities = 55/208 (26%), Positives = 96/208 (45%), Gaps = 5/208 (2%) Query: 144 LNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYAMFKRPITVETVMKSPYIADPLKL 203 + L+ ++ G E LA+ A G NP A P+T+ V+ + + DPL Sbjct: 117 IGGLMANAFLARTGLGREALAMVAAKNKNAGLSNPRASHAAPVTLGDVLSAKPVVDPLTG 176 Query: 204 FDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMGRAIDTINLANREDLLTLKAAKI 263 +D +P D A +++ E A+ L W+E G T +LA + ++ + ++ Sbjct: 177 YDIAPFSDAAIVMLVASEEAARRL-TDTPVWIEGVGWSTESGTGSLAWHQ-WDSMPSIRM 234 Query: 264 AAEKAYKMAKVEPKD---IDFFEVHDAFTVMAALSLEALGVAEKGEGAKLAKEGQIAIDG 320 A + A MA + + F E+ D ++ M LS+E G+A E + + G G Sbjct: 235 AVDMAKSMAGLSGRPQTFTSFAELEDRYSFMEILSMEEAGIAGPEEAYSMLEAGDTEPSG 294 Query: 321 DYPIQTMGGLKARGHPVGATGVYQTVES 348 +YP+ GG A G + ATG ++ +E+ Sbjct: 295 NYPVNPSGGSLAAGVALEATGGFRVLEA 322 >dbj|BAB11319.1| (AB016886) acetoacyl-CoA-thiolase [Arabidopsis thaliana] Length = 415 Score = 78.4 bits (190), Expect = 1e-13 Identities = 95/391 (24%), Positives = 163/391 (41%), Gaps = 95/391 (24%) Query: 6 IVGVGMTPVGEHW-------RTSLRDLAVEAILKAMDDAGIDK--VDSLYVGNMASGSFV 56 +VGV TP+G+ T L +A++A LK A +D V+ ++ GN+ + Sbjct: 17 VVGVARTPIGDFLGSLSSLTATRLGSIAIQAALKR---AHVDPALVEEVFFGNVLTA--- 70 Query: 57 EQENLGALIADWAGLG-----NIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVE 111 NLG A A LG ++ + CA+G +V ++++ GL D+V+ G+E Sbjct: 71 ---NLGQAPARQAALGAGIPYSVICTTINKVCAAGMKSVMLASQSIQLGLNDIVVAGGME 127 Query: 112 KMTDA--WPSDATR---------YLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTE 160 M++ + DA R D W++++ + + Y T Sbjct: 128 SMSNVPKYLPDARRGSRLGHDTVVDGMMKDGLWDVYNDFGMGVCGEIC----ADQYRITR 183 Query: 161 EDLALFAVNAHANG--AKNP--YAMFKRPITVETVMKSPYIA----DPLKLFD------- 205 E+ +A+ + G A+N +A P+ V T P + + L FD Sbjct: 184 EEQDAYAIQSFERGIAAQNTQLFAWEIVPVEVSTGRGRPSVVIDKDEGLGKFDAAKLKKL 243 Query: 206 ---------------ASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMGRAIDTINLA 250 AS + DGAAA+++ EKA ELG+ +I G A A Sbjct: 244 RPSFKEDGGSVTAGNASSISDGAAALVLVSGEKALELGL--HVIAKIRGYADA------A 295 Query: 251 NREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALGVAEKGEGAKL 310 +L T A +A KA K A ++ +D++E+++AF+V+A + + LG+ + Sbjct: 296 QAPELFTTTPA-LAIPKAIKRAGLDASQVDYYEINEAFSVVALANQKLLGLDPE------ 348 Query: 311 AKEGQIAIDGDYPIQTMGGLKARGHPVGATG 341 + GG + GHP+G +G Sbjct: 349 ------------RLNAHGGAVSLGHPLGCSG 367 >pir||D70808 probable regulatory protein - Mycobacterium tuberculosis (strain H37RV) >gi|2924459|emb|CAA17759.1| (AL022022) hypothetical protein Rv3522 [Mycobacterium tuberculosis] Length = 354 Score = 71.8 bits (173), Expect = 1e-11 Identities = 85/342 (24%), Positives = 142/342 (40%), Gaps = 26/342 (7%) Query: 24 DLAVEAILKAMDDAGIDKVDSLYVGNMASGSFVEQENLG-ALIADWAGLGNIPAVKVEAA 82 ++ + + D+ GI K D +G SGS + I+ +G +P + Sbjct: 28 EMLMPCFAQLYDELGITKAD---IGFWCSGSSDYLAGRAFSFISAIDSIGAVPPINESHV 84 Query: 83 CASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDATRYLAYASDAEWELFHGVSFV 142 A+ E +L+G D LV G K + R L+ +D V Sbjct: 85 EMDAAWALYEAYIKLLTGEVDTALVYGFGKSS---AGTLRRVLSRQTDPYTVAPLWPDSV 141 Query: 143 ALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYAMFKRPITVETVMKSPYIADPLK 202 ++ L R +++ +T E +A A ++ N + + PITV ++ P+ ADPL+ Sbjct: 142 SMAGLQARLGLDSGKWTHEQMARVAFDSFTNARR--VDSVEPPITVGELLARPFFADPLR 199 Query: 203 LFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMGRAIDTINLANREDLLTLKAAK 262 D +P+ DGAAAV++ +A+EL ++ I G+ I++ L R D+ + K Sbjct: 200 RHDIAPITDGAAAVVLAADNRAREL---RENPAWITGIEHRIESPALGAR-DITESPSTK 255 Query: 263 IAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALGVAEKGE----GAKLAKEGQIAI 318 +AA+ A DID E+H FT + EA+ + K + G LA A Sbjct: 256 LAAKIA---TGGHTGDIDVAEIHGPFTHQHLIVAEAIRIPGKTKVNPSGGPLAANPMFAA 312 Query: 319 D----GDYPIQTMGGLKAR--GHPVGATGVYQTVESVLQIRG 354 G T G R H + Q + +V++ RG Sbjct: 313 GLERIGFAAQHTWDGSARRVLAHATSGPALQQNLVAVMEGRG 354 >gb|AAG17184.1|AF191029_2 (AF191029) FadA [Enterobacter cloacae] Length = 387 Score = 71.0 bits (171), Expect = 2e-11 Identities = 105/424 (24%), Positives = 173/424 (40%), Gaps = 73/424 (17%) Query: 1 MEKPIIVGVGMTPVGEHWRTSLRDLAVEAILK-----------AMDDAGIDKVDSLYVGN 49 MEK +IV TP+G + R++ E + A+D A +D + + Sbjct: 1 MEKVVIVDAIRTPMGRSKGGAFRNVRAEDLSAHLMRSLLARNPALDPAALDDIYWGCLHQ 60 Query: 50 MASGSFVEQENLGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVG 109 F N +L+A+ ++PAV V C S A+ + A+ +++G LV G Sbjct: 61 TLEQGFNLARN-ASLLAEIPH--SVPAVTVNRLCGSSMQALHDAARMIMTGDAQACLVGG 117 Query: 110 VEKMTDAWPSDA-------TRYLAYAS-----DAEW-ELFHGVSFVALNALIMRHYMNTY 156 VE M S +R +A A+ AE HG+S +A R + + Sbjct: 118 VEHMGHVPMSHGVHFHPGMSRNVAKAAGMMGLTAEMLSRLHGISREMQDAFAARSHARAW 177 Query: 157 GYTEEDL---ALFAVNAH-ANGAKNPYA---MFKRPITVETVMKSPYIADP----LKLFD 205 T+ + H A+G ++ + + TVE + DP + Sbjct: 178 AATQSGAFKNEIIPTGGHDADGVLKQFSYDEVIRPETTVEALSTLRPAFDPVTGTVTAGT 237 Query: 206 ASPVCDGAAAVIITIPEKAKELGI-PKDKWVEIAGMGRAIDTINLANREDLLTLKAAKIA 264 +S + DGAAA+++ +A+ELG+ P+ + +A +G + + A+K+A Sbjct: 238 SSALSDGAAAMLVMSESRARELGLTPRARVRSMAVVGCDPSIMGYG------PVPASKLA 291 Query: 265 AEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPI 324 +KA A DID FE+++AF ++ LG+ GQI D I Sbjct: 292 LKKAGLTA----SDIDLFEMNEAFAAQILPCIKDLGLM-----------GQI----DEKI 332 Query: 325 QTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTI 384 GG A GHP+G +G + + + G+ DA+ GL G G I T+ Sbjct: 333 NLNGGAIALGHPLGCSGARISTTLINLMEGK--------DAQFGLATMCIGLGQGI-ATV 383 Query: 385 LRRV 388 RV Sbjct: 384 FERV 387 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.316 0.134 0.385 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 138531070 Number of Sequences: 2977 Number of extensions: 5588998 Number of successful extensions: 15332 Number of sequences better than 1.0e-10: 68 Number of HSP's better than 0.0 without gapping: 42 Number of HSP's successfully gapped in prelim test: 26 Number of HSP's that attempted gapping in prelim test: 15095 Number of HSP's gapped (non-prelim): 76 length of query: 388 length of database: 189,106,746 effective HSP length: 58 effective length of query: 330 effective length of database: 154,394,500 effective search space: 50950185000 effective search space used: 50950185000 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.6 bits) S2: 166 (69.1 bits)