BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB0907 (acaB) DE:3-ketoacyl-CoA thiolase (acaB)
         (388 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||F75047 3-ketoacyl-coa thiolase (acab) PAB0907 - Pyrococcus ...   771  0.0
pir||E71113 probable nonspecific lipid-transfer protein - Pyroco...   741  0.0
pir||T45081 3-ketoacyl-CoA thiolase (acaB-12) homolog [imported]...   725  0.0
pir||G69205 lipid-transfer protein (sterol or nonspecific) - Met...   349  3e-95
gi|11499992 3-ketoacyl-CoA thiolase (acaB-12) [Archaeoglobus ful...   344  1e-93
pir||D64493 nonspecific lipid-transfer protein homolog - Methano...   328  5e-89
emb|CAC12576.1| (AL445067) probable 3-ketoacyl-CoA thiolase [The...   296  4e-79
gi|11497899 3-ketoacyl-CoA thiolase (acaB-7) [Archaeoglobus fulg...   276  3e-73
gi|11498050 3-ketoacyl-CoA thiolase (acaB-8) [Archaeoglobus fulg...   268  1e-70
gb|AAK42745.1| Acetyl-CoA c-acetyltransferase (acetoacetyl-CoA t...   265  7e-70
pir||A72689 probable nonspecific lipid-transfer protein APE0929 ...   263  2e-69
gb|AAK42980.1| Acetyl-CoA c-acetyltransferase (acetoacetyl-CoA t...   263  3e-69
gb|AAG19170.1| (AE005014) 3-ketoacyl-CoA thiolase; AcaB1 [Haloba...   256  2e-67
gb|AAG19361.1| (AE005031) 3-ketoacyl-CoA thiolase; AcaB2 [Haloba...   256  2e-67
emb|CAC11179.1| (AL445063) probable acetyl CoA synthase [Thermop...   252  4e-66
gi|11498889 3-ketoacyl-CoA thiolase (acaB-11) [Archaeoglobus ful...   247  2e-64
gi|11497655 3-ketoacyl-CoA thiolase (acaB-2) [Archaeoglobus fulg...   244  1e-63
gb|AAK42810.1| Acetyl-CoA c-acetyltransferase (acetoacetyl-CoA t...   234  1e-60
gi|11497639 3-ketoacyl-CoA thiolase (acaB-1) [Archaeoglobus fulg...   222  4e-57
pir||H72573 probable acetyl CoA synthase APE1872 - Aeropyrum per...   206  3e-52
gb|AAF89837.1|AF173961_3 (AF173961) putative benzoylsuccinyl-CoA...   190  2e-47
emb|CAC11495.1| (AL445064) sterol carrier protein x/sterol carri...   190  3e-47
gi|11497818 3-ketoacyl-CoA thiolase (acaB-6) [Archaeoglobus fulg...   189  4e-47
emb|CAB55378.1| (AL117263) possible 3-ketoacyl-CoA thiolase [Lei...   185  9e-46
gb|AAK42246.1| Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA t...   172  5e-42
pir||A39368 sterol carrier protein 2 precursor - rat >gi|202553|...   169  3e-41
pir||E70884 probable lipid-transfer protein - Mycobacterium tube...   168  1e-40
emb|CAA43061.1| (X60654) open reading frame for 58 kDa protein  ...   168  1e-40
gb|AAB27044.1| 3-oxoacyl-CoA thiolase homolog {N-terminal} [rats...   168  1e-40
sp|P11915|NLTP_RAT NONSPECIFIC LIPID-TRANSFER PROTEIN PRECURSOR ...   167  2e-40
pir||A70559 hypothetical protein Rv1627c - Mycobacterium tubercu...   167  2e-40
gb|AAA42122.1| (M57453) sterol carrier protein-x [Rattus norvegi...   167  2e-40
sp|P32020|NLTP_MOUSE NONSPECIFIC LIPID-TRANSFER PROTEIN PRECURSO...   165  9e-40
gi|11498572 3-ketoacyl-CoA thiolase (acaB-9) [Archaeoglobus fulg...   163  3e-39
sp|P22307|NLTP_HUMAN NONSPECIFIC LIPID-TRANSFER PROTEIN PRECURSO...   162  6e-39
gb|AAB41286.1| (U11313) sterol carrier protein-X/sterol carrier ...   159  4e-38
gb|AAC15422.1| (AF051897) sterol carrier protein X [Oryctolagus ...   159  7e-38
pir||A34635 nonspecific lipid transfer protein precursor - rat  ...   159  7e-38
gb|AAF53713.1| (AE003660) ScpX gene product [Drosophila melanoga...   157  2e-37
sp|Q07598|NLTP_CHICK NONSPECIFIC LIPID-TRANSFER PROTEIN PRECURSO...   156  3e-37
pir||B40407 sterol carrier protein 2-related form, 58.85K - human     153  3e-36
gb|AAF53712.1| (AE003660) CG17597 gene product [Drosophila melan...   152  9e-36
gb|AAK40853.1| Acetyl-CoA c-acetyltransferase (acetoacetyl-CoA t...   150  2e-35
emb|CAB57766.1| (Y18930) acetyl CoA synthase [Sulfolobus solfata...   150  2e-35
pir||G72467 probable non specific lipid-transfer protein APE2384...   148  1e-34
gi|11497751 3-ketoacyl-CoA thiolase (acaB-4) [Archaeoglobus fulg...   145  1e-33
pir||T27202 hypothetical protein Y57A10C.6 - Caenorhabditis eleg...   144  1e-33
emb|CAA66277.1| (X97685) sterol carrier protein x [Drosophila me...   141  1e-32
gi|11497750 3-ketoacyl-CoA thiolase (acaB-3) [Archaeoglobus fulg...   140  2e-32
emb|CAA64718.1| (X95443) sterol carrier protein x-related thiola...   138  1e-31
pir||E70676 probable nonspecific lipid-transfer protein Rv3540c ...   135  1e-30
pir||A83518 hypothetical protein PA1016 [imported] - Pseudomonas...   132  6e-30
pir||D70674 probable lipid carrier protein - Mycobacterium tuber...   125  8e-28
gb|AAB48108.1| (U41818) PhlC [Pseudomonas fluorescens]                125  8e-28
pir||B70582 probable lipid-transfer protein - Mycobacterium tube...   123  3e-27
gi|11498573 3-ketoacyl-CoA thiolase (acaB-10) [Archaeoglobus ful...   123  4e-27
pir||T50937 DitF protein [imported] - Pseudomonas abietaniphila ...   113  3e-24
gb|AAK42245.1| Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA t...   107  3e-22
gb|AAK43216.1| Acetyl-CoA c-acetyltransferase (acetoacetyl-CoA t...   106  3e-22
gb|AAK42641.1| Acetyl-CoA c-acetyltransferase (acetoacetyl-CoA t...   106  5e-22
gi|4506823 sterol carrier protein 2 [Homo sapiens] >gi|432977|gb...    97  3e-19
gb|AAA42120.1| (M34728) sterol carrier protein-2 (SCP-2) [Rattus...    94  2e-18
gi|11497817 3-ketoacyl-CoA thiolase (acaB-5) [Archaeoglobus fulg...    93  4e-18
emb|CAC00412.1| (AL160371) possible thiolase [Leishmania major]        89  7e-17
pir||E72467 probable non specific lipid-transfer protein APE2382...    82  1e-14
dbj|BAB11319.1| (AB016886) acetoacyl-CoA-thiolase [Arabidopsis t...    78  1e-13
pir||D70808 probable regulatory protein - Mycobacterium tubercul...    72  1e-11
gb|AAG17184.1|AF191029_2 (AF191029) FadA [Enterobacter cloacae]        71  2e-11

>pir||F75047 3-ketoacyl-coa thiolase (acab) PAB0907 - Pyrococcus abyssi  (strain
           Orsay) >gi|5458788|emb|CAB50275.1| (AJ248287)
           3-ketoacyl-CoA thiolase (acaB) [Pyrococcus abyssi]
           Length = 388
           
 Score =  771 bits (1969), Expect = 0.0
 Identities = 388/388 (100%), Positives = 388/388 (100%)

Query: 1   MEKPIIVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVDSLYVGNMASGSFVEQEN 60
           MEKPIIVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVDSLYVGNMASGSFVEQEN
Sbjct: 1   MEKPIIVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVDSLYVGNMASGSFVEQEN 60

Query: 61  LGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSD 120
           LGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSD
Sbjct: 61  LGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSD 120

Query: 121 ATRYLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYA 180
           ATRYLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYA
Sbjct: 121 ATRYLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYA 180

Query: 181 MFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGM 240
           MFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGM
Sbjct: 181 MFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGM 240

Query: 241 GRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALG 300
           GRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALG
Sbjct: 241 GRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALG 300

Query: 301 VAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGI 360
           VAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGI
Sbjct: 301 VAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGI 360

Query: 361 QVPDAEIGLTQNIGGTGSNITVTILRRV 388
           QVPDAEIGLTQNIGGTGSNITVTILRRV
Sbjct: 361 QVPDAEIGLTQNIGGTGSNITVTILRRV 388


>pir||E71113 probable nonspecific lipid-transfer protein - Pyrococcus horikoshii
           >gi|3257084|dbj|BAA29767.1| (AP000003) 389aa long
           hypothetical nonspecific lipid-transfer protein (acethyl
           CoA synthetase) [Pyrococcus horikoshii]
           Length = 389
           
 Score =  741 bits (1891), Expect = 0.0
 Identities = 366/386 (94%), Positives = 378/386 (97%)

Query: 3   KPIIVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVDSLYVGNMASGSFVEQENLG 62
           K IIVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVDSLYVGNMASGSF+EQENLG
Sbjct: 4   KVIIVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVDSLYVGNMASGSFIEQENLG 63

Query: 63  ALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDAT 122
           ALIADWAGLGNIPAVK+EAACASGGAAVQEG KAVLSGLEDVVLVVGVEKMTDAWPSDAT
Sbjct: 64  ALIADWAGLGNIPAVKIEAACASGGAAVQEGVKAVLSGLEDVVLVVGVEKMTDAWPSDAT 123

Query: 123 RYLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYAMF 182
           RYLAYASDAEWELFHGVSFVALNAL+MR+YMNTYGYTEEDLALFAVNAHANGAKNPYAMF
Sbjct: 124 RYLAYASDAEWELFHGVSFVALNALVMRYYMNTYGYTEEDLALFAVNAHANGAKNPYAMF 183

Query: 183 KRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMGR 242
           K+PITVETVMKSPYIADPLKLFDASPVCDGAAAVIIT PEKAKELG+PKDKWVE+AGMGR
Sbjct: 184 KKPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITTPEKAKELGVPKDKWVEVAGMGR 243

Query: 243 AIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALGVA 302
           AIDTINLANREDLLTLKAAKIAAEKAYKMA VEPKDIDFFEVHDAFT+MAALSLEALGVA
Sbjct: 244 AIDTINLANREDLLTLKAAKIAAEKAYKMAHVEPKDIDFFEVHDAFTIMAALSLEALGVA 303

Query: 303 EKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGIQV 362
           EKG+GA LAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQ VE+ LQ+RGEAPNGIQV
Sbjct: 304 EKGKGAMLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQAVEATLQLRGEAPNGIQV 363

Query: 363 PDAEIGLTQNIGGTGSNITVTILRRV 388
           PDAE+GLTQNIGGTGSNITVTI RRV
Sbjct: 364 PDAEVGLTQNIGGTGSNITVTIFRRV 389


>pir||T45081 3-ketoacyl-CoA thiolase (acaB-12) homolog [imported] - Pyrococcus
           furiosus >gi|1197356|emb|CAA59498.1| (X85250) acetyl CoA
           synthase [Pyrococcus furiosus]
           Length = 388
           
 Score =  725 bits (1851), Expect = 0.0
 Identities = 360/388 (92%), Positives = 375/388 (95%)

Query: 1   MEKPIIVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVDSLYVGNMASGSFVEQEN 60
           M K IIVGVGMTPVGEHWR+SLRDLAVEAIL AMDDAGIDKVDSLYVGNMASGSFVEQEN
Sbjct: 1   MRKAIIVGVGMTPVGEHWRSSLRDLAVEAILNAMDDAGIDKVDSLYVGNMASGSFVEQEN 60

Query: 61  LGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSD 120
           LGALIADWAGLGNIPAVK+EAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSD
Sbjct: 61  LGALIADWAGLGNIPAVKIEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSD 120

Query: 121 ATRYLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYA 180
           ATRYL YA+DAEWELFHG SFVALNALIMR YMNTYGY EEDLALFAVNAHANGAKNPYA
Sbjct: 121 ATRYLGYAADAEWELFHGASFVALNALIMRLYMNTYGYKEEDLALFAVNAHANGAKNPYA 180

Query: 181 MFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGM 240
           MFK+PITVETVMKSPYIADPLKLFDASPVCDGAAAVIIT PEKAKELGIPKDKW+EIAGM
Sbjct: 181 MFKKPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITTPEKAKELGIPKDKWIEIAGM 240

Query: 241 GRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALG 300
           GRAIDTINLANRED LTLKAA IAAE+AYKMA V+P+D+DFFEVHDAFTVMAALSLEALG
Sbjct: 241 GRAIDTINLANREDFLTLKAATIAAERAYKMAGVKPEDVDFFEVHDAFTVMAALSLEALG 300

Query: 301 VAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGI 360
           VA+KGEGAKLA EGQIAIDGDYPIQTMGGLKARGHPVGATGVYQ VE+VLQ+RGEAP+GI
Sbjct: 301 VAKKGEGAKLAIEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQVVEAVLQLRGEAPDGI 360

Query: 361 QVPDAEIGLTQNIGGTGSNITVTILRRV 388
           QVPDAE+GLTQNIGGTGSNITVT+LRRV
Sbjct: 361 QVPDAEVGLTQNIGGTGSNITVTVLRRV 388


>pir||G69205 lipid-transfer protein (sterol or nonspecific) - Methanobacterium
           thermoautotrophicum (strain Delta H)
           >gi|2621882|gb|AAB85293.1| (AE000857) lipid-transfer
           protein (sterol or nonspecific) [Methanobacterium
           thermoautotrophicum]
           Length = 383
           
 Score =  349 bits (886), Expect = 3e-95
 Identities = 189/389 (48%), Positives = 247/389 (62%), Gaps = 8/389 (2%)

Query: 1   MEKPIIVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGID--KVDSLYVGNMASGSFVEQ 58
           M    ++GV  T  GE W  S RD+  EA L A++DAG++   +D++YVGNM++G F++Q
Sbjct: 1   MRDVAVIGVSQTKFGELWDVSFRDMITEAGLGAIEDAGVEGADLDAMYVGNMSAGLFIKQ 60

Query: 59  ENLGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWP 118
           E++ +LIAD AGL  IP+ +VEAACASGG A++ G  AV SG  D+V+  GVEKMTD   
Sbjct: 61  EHISSLIADHAGLTPIPSTRVEAACASGGLALRSGIMAVASGYHDIVIAAGVEKMTDV-- 118

Query: 119 SDATRYLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNP 178
            D T  +A ASD EWE   GV+F +L A++ R +M  YG T E LA+ +V  H N + NP
Sbjct: 119 VDPTPAIATASDQEWEAQQGVTFPSLYAMMARRHMYEYGTTREQLAMVSVINHENASNNP 178

Query: 179 YAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIA 238
            A F   +TVE VM S  +ADPL+L D SP+ DGAAAVI+   + A+E     D  V + 
Sbjct: 179 RAQFPMKVTVEQVMNSTMVADPLRLLDCSPISDGAAAVILCPADMAREY---TDTPVYVK 235

Query: 239 GMGRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEA 298
              +A  TI L +R D+  + A   AA  A+KMAK+ P DID  EVHD F++   L++E 
Sbjct: 236 ASAQASGTIALHDRRDITRIDATVNAARNAFKMAKLTPGDIDLVEVHDCFSINGILAVED 295

Query: 299 LGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPN 358
           LG  EKGEG +  ++G   IDGD P+   GGLKARGHP+GATG+ Q  E V Q+RGEA  
Sbjct: 296 LGFVEKGEGGRAFEDGMTRIDGDIPVNPSGGLKARGHPLGATGIAQAAEVVWQLRGEAGK 355

Query: 359 GIQVPDAEIGLTQNIGGTGSNITVTILRR 387
             QV  AEIG+T NIGGTG    V I  R
Sbjct: 356 R-QVEGAEIGMTHNIGGTGGTAAVHIFSR 383


>gi|11499992 3-ketoacyl-CoA thiolase (acaB-12) [Archaeoglobus fulgidus]
           >gi|7450462|pir||A69552 3-ketoacyl-CoA thiolase
           (acaB-12) homolog - Archaeoglobus fulgidus
           >gi|2650673|gb|AAB91246.1| (AE001108) 3-ketoacyl-CoA
           thiolase (acaB-12) [Archaeoglobus fulgidus]
           Length = 384
           
 Score =  344 bits (873), Expect = 1e-93
 Identities = 191/391 (48%), Positives = 260/391 (65%), Gaps = 11/391 (2%)

Query: 1   MEKPIIVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGID--KVDSLYVGNMASGSFVEQ 58
           M +  +VGVG +  GE W    RD+ +EA  +A++DA ++  ++++++VGNM+ G ++ Q
Sbjct: 1   MRRVAVVGVGQSKFGELWEKGFRDIVLEAGREALEDADLEGREIEAMFVGNMSGGRYLGQ 60

Query: 59  ENLGALIADWAGLGN--IPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDA 116
           E++ ALIAD+AGL    IPA +VEAA ASGG AV++   AV SGL D+V+  G EK+TD 
Sbjct: 61  EHVAALIADYAGLAEFGIPATRVEAADASGGLAVRQAYMAVASGLHDIVIAAGAEKVTDV 120

Query: 117 WPSDATRYLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAK 176
              D  + L+ + D EWE F G S  AL A+I R +M+++G TEEDLAL +V  H NGAK
Sbjct: 121 --DDPMQILSSSVDVEWENFVGGSLPALYAIIARLHMDSFGTTEEDLALVSVKNHRNGAK 178

Query: 177 NPYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVE 236
           NP A F++ I VE V+ SPY+A+PLKL D + V DGAAAVI+   + A+E+    D  V 
Sbjct: 179 NPKAQFRKEIRVEDVLNSPYVAEPLKLLDCASVSDGAAAVILASEDVAREI---TDTPVF 235

Query: 237 IAGMGRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSL 296
           I    +A D + L +R+D+L+++A   A+  AY++A V PKDI   EVHD+FT+   L+ 
Sbjct: 236 IEACTQASDYLALQSRKDILSMRAVVKASRDAYELAGVGPKDIQVAEVHDSFTIAEILAY 295

Query: 297 EALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEA 356
           E LG AEKG+GA+L +EG   I G  P+   GGLKA GH VGATGV Q VE  LQ+RGEA
Sbjct: 296 EDLGFAEKGKGAELVREGVTEIGGKIPVNPSGGLKACGHAVGATGVRQIVELTLQLRGEA 355

Query: 357 PNGIQVPDAEIGLTQNIGGTGSNITVTILRR 387
             G +  DAE GL  NIGGTG+   V+ILRR
Sbjct: 356 --GERQVDAETGLALNIGGTGATAVVSILRR 384


>pir||D64493 nonspecific lipid-transfer protein homolog - Methanococcus
           jannaschii >gi|1592180|gb|AAB99567.1| (U67595)
           3-keto-acyl-CoA thiolase [Methanococcus jannaschii]
           Length = 392
           
 Score =  328 bits (833), Expect = 5e-89
 Identities = 184/395 (46%), Positives = 253/395 (63%), Gaps = 17/395 (4%)

Query: 1   MEKPIIVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGID--KVDSLYVGNMASGSFVEQ 58
           M    I+G G T  GE W  S R L VEA +KA++ AGID   +D +YVGNM++G FV Q
Sbjct: 1   MRDVAIIGYGQTKFGELWERSFRSLIVEAGVKAVEAAGIDGKDIDEMYVGNMSAGLFVGQ 60

Query: 59  ENLGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWP 118
           E++ +LIA+ AGL  IP+ +VEAACASG  A+++    V SG  DVVLV GVEKMTD   
Sbjct: 61  EHIASLIAEHAGLNPIPSTRVEAACASGSLALRQAVLNVASGASDVVLVGGVEKMTDV-- 118

Query: 119 SDATRYLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNP 178
            DAT  ++ ASD EWE   G +F +L A++ + YM  YG T E+L++++V  H N +KN 
Sbjct: 119 VDATSAISSASDQEWEALFGATFPSLYAMMAQRYMYEYGLTLEELSMWSVIMHENASKNR 178

Query: 179 YAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIA 238
           YA F   +T+E V+ S  +A+PL+L   SPV DGAAA+I+   EKAKE  + KD  + I 
Sbjct: 179 YAQFPFKVTLEQVLNSSPVAEPLRLLHCSPVSDGAAALIVCEAEKAKEF-VNKDDIIYIK 237

Query: 239 GMGRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEA 298
              +A DTI L +RE + +LKAAK+A+EKAYKMA +EPKD+D  EVHD F +   + +E 
Sbjct: 238 ASVQASDTIALHSRESITSLKAAKVASEKAYKMANIEPKDVDVAEVHDCFAINGLILMEE 297

Query: 299 LGVAEKGEGAKLAKEGQIAIDGD-YP-IQTMGGLKARGHPVGATGVYQTVESVLQIRGEA 356
           LG  +KGE  K+  + +IAID D +P +   GGLKA GH +GATG+ Q  E   Q++ + 
Sbjct: 298 LGFCKKGEAGKIVYDKKIAIDYDGFPAVNPSGGLKAAGHALGATGIRQVGEIYWQLKQDK 357

Query: 357 PNGIQVPDAEI------GLTQNIGGTGSNITVTIL 385
               +V D ++      G+T N+GGTG  + + IL
Sbjct: 358 ----EVKDRQVEIKNGYGITVNVGGTGGTVCIHIL 388


>emb|CAC12576.1| (AL445067) probable 3-ketoacyl-CoA thiolase [Thermoplasma
           acidophilum]
           Length = 387
           
 Score =  296 bits (749), Expect = 4e-79
 Identities = 167/384 (43%), Positives = 243/384 (62%), Gaps = 10/384 (2%)

Query: 6   IVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVD--SLYVGNMASGSFVEQENLGA 63
           I+G G T  GE W  SLRDLAVEA L+A+ DA I   D   LY  N  +G+  EQ N+ A
Sbjct: 8   IIGAGETKFGELWDKSLRDLAVEAGLEAIKDANIYSRDLQMLYASNSLAGTINEQSNIAA 67

Query: 64  LIADWAGLG--NIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDA 121
           L AD++G+   ++PAV+VEA+ ASGGAAV+E   A+ SG  DVV+V GVEKMTD + S+ 
Sbjct: 68  LAADFSGIAETHVPAVRVEASTASGGAAVREAYLAIKSGEYDVVMVGGVEKMTDIYGSEI 127

Query: 122 TRYLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYAM 181
               +   D EWE F+G +  AL A+  R YM+ +    ED+A+ AVN HAN + NP A 
Sbjct: 128 IDVQSSILDREWESFNGATPAALAAITARRYMHDFKVPREDIAMIAVNDHANASMNPDAQ 187

Query: 182 FKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMG 241
           ++  ITVE V+ S  +A+PL +FD SP+ DGA+A+I+   E  K+  +     + I    
Sbjct: 188 YRNKITVEQVINSDPVAEPLNVFDCSPISDGASAIILASDEYRKKNRL---DGIRIVSSA 244

Query: 242 RAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALGV 301
            + D + L +R+ + TL++A+IA+++A + A ++  DI F E++D++++   L LE LG 
Sbjct: 245 MSEDYLALHSRKSIYTLESARIASKQALERAGIKKNDISFLELNDSYSIYGLLELEDLGF 304

Query: 302 AEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGIQ 361
           AEKG+G +L   G+I I+G  P+   GGLKA+G+P+GATGV Q  E+ LQ++G+A    Q
Sbjct: 305 AEKGKGRELL--GEIKINGSLPVNPSGGLKAKGNPLGATGVSQFYEAYLQLKGKAGQR-Q 361

Query: 362 VPDAEIGLTQNIGGTGSNITVTIL 385
           V  A  G+  N+ GTG+   V I+
Sbjct: 362 VKGARYGMLHNMAGTGATSVVHIV 385


>gi|11497899 3-ketoacyl-CoA thiolase (acaB-7) [Archaeoglobus fulgidus]
           >gi|7450468|pir||C69285 3-ketoacyl-CoA thiolase (acaB-7)
           homolog - Archaeoglobus fulgidus
           >gi|2650353|gb|AAB90950.1| (AE001085) 3-ketoacyl-CoA
           thiolase (acaB-7) [Archaeoglobus fulgidus]
           Length = 396
           
 Score =  276 bits (699), Expect = 3e-73
 Identities = 167/390 (42%), Positives = 227/390 (57%), Gaps = 10/390 (2%)

Query: 2   EKPIIVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVDSLYVGNMASGSFVEQENL 61
           E   ++GVG +  G     ++ +L  E++  A + A ++  D  +     +G +  +  +
Sbjct: 4   ENVAVIGVGHSKFGTRKDVNIAELCWESMKPAFESANLEPKDIEFFVVSNAGMWSSEAAV 63

Query: 62  GALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDA 121
            AL+A++A L    +++VEAACASG AAV+ G  AV SG+ D+VLV+GVEKM ++   + 
Sbjct: 64  PALMAEYADLAPKGSMRVEAACASGSAAVRVGYTAVKSGMADIVLVLGVEKMQESPNPNV 123

Query: 122 TRYLAYASDAEWELFH-GVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYA 180
              +       WE  + G++F A  AL    YM  YG TEED A  AV  H  GAKNPYA
Sbjct: 124 IELIGRFGSYFWEFENFGLTFPAYYALHGTAYMMKYGATEEDYAKVAVKNHYYGAKNPYA 183

Query: 181 MFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGM 240
            F+R I VETVMKSPY+A P KLFD SP+ DG+A +I+   EK KELGI +  W  I G 
Sbjct: 184 QFQREIDVETVMKSPYVAWPFKLFDCSPITDGSACIILASEEKVKELGIDEKIW--ILGQ 241

Query: 241 GRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKD----IDFFEVHDAFTVMAALSL 296
           G    T NL+ RE+  +L +A  AAE+AYKMA ++  D    +D   VHD FT    ++ 
Sbjct: 242 GVGTGTANLSRREEFSSLASATYAAEQAYKMAGIDIDDPTKYLDGANVHDCFTAPEIIAY 301

Query: 297 EALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEA 356
           E L   ++GEG KL +E Q  I G  P+   GGLKA+GHP+GATGV Q VE+  Q+  +A
Sbjct: 302 EDLRFCKRGEGYKLIREEQTYIGGKIPVNVDGGLKAKGHPIGATGVSQAVEAYKQLLQKA 361

Query: 357 PNGIQVPDAEIG--LTQNIGGTGSNITVTI 384
             G Q  D   G  L  N+GGTG    VTI
Sbjct: 362 EPGRQA-DINKGRWLAHNVGGTGHYSYVTI 390


>gi|11498050 3-ketoacyl-CoA thiolase (acaB-8) [Archaeoglobus fulgidus]
           >gi|7450467|pir||F69304 3-ketoacyl-CoA thiolase (acaB-8)
           homolog - Archaeoglobus fulgidus
           >gi|2650194|gb|AAB90795.1| (AE001074) 3-ketoacyl-CoA
           thiolase (acaB-8) [Archaeoglobus fulgidus]
           Length = 387
           
 Score =  268 bits (677), Expect = 1e-70
 Identities = 157/388 (40%), Positives = 223/388 (57%), Gaps = 11/388 (2%)

Query: 6   IVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGI--DKVDSLYVGNMASGSFVEQENLGA 63
           ++GVG +  G      +++LA EA+ +A+DDAGI  D+V+   VG++ +  +   E + A
Sbjct: 5   VIGVGCSRFGRRDDAVIQELAYEAVKEALDDAGITQDEVELSVVGSVNTRGY---ELMPA 61

Query: 64  L-IADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDAT 122
           + + ++ G      ++VEAACA+G AAV     ++ SG+ DV + +GVEKMT+   + + 
Sbjct: 62  VPVNEYCGFAGKGPLRVEAACATGAAAVYTAYTSIASGMADVAIAIGVEKMTEVDTATSL 121

Query: 123 RYLAYASDAEWELF-HGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYAM 181
                A +  WE   +G +F A  A+    +M  YG TEE +A  AV AH N A+NP A 
Sbjct: 122 AIGGRAGNYLWEFHQYGTTFPAYYAMHATAHMAKYGTTEEQMAKVAVKAHRNAARNPKAH 181

Query: 182 FKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMG 241
           F++ I VE V+ S YI  PLKL+D SP+ DG+AA I+   EK +ELGI    W++   +G
Sbjct: 182 FQKEIAVEDVLNSRYITYPLKLYDCSPISDGSAAAILASEEKIRELGIDDVVWID--SVG 239

Query: 242 RAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEP--KDIDFFEVHDAFTVMAALSLEAL 299
            A DT N+ NRE  + LKA  +A E AY+ A +E   K +DF  VHD FT+   ++ E L
Sbjct: 240 YASDTSNMTNRESFVGLKATVLAREMAYRKAGIEEPVKQLDFATVHDCFTIAEIMAYEDL 299

Query: 300 GVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNG 359
           G   KGEG KL + G+  + G  P+ T GGLKA+GHP+ ATGV    E V Q+RGEA   
Sbjct: 300 GFCRKGEGGKLVESGETELGGKLPVNTFGGLKAKGHPLAATGVAMVYEIVKQLRGEAGEL 359

Query: 360 IQVPDAEIGLTQNIGGTGSNITVTILRR 387
                    L  N+GGTG    V I  R
Sbjct: 360 QVELRNNRALLHNVGGTGHFAFVMIFGR 387


>gb|AAK42745.1| Acetyl-CoA c-acetyltransferase (acetoacetyl-CoA thiolase) (acaB-7)
           [Sulfolobus solfataricus]
           Length = 387
           
 Score =  265 bits (670), Expect = 7e-70
 Identities = 154/386 (39%), Positives = 221/386 (56%), Gaps = 9/386 (2%)

Query: 6   IVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVDSLYVGNMASGSFVEQE---NLG 62
           ++GVG +  G     S+++LA E+I +A++D+G+ + D   +G +  GS   +       
Sbjct: 7   VIGVGNSKFGRRDDVSIQELAWESIKEALNDSGVSQSD---IGLVVIGSTAYRGIELYPA 63

Query: 63  ALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDAT 122
            ++A+++GL     ++VEA CA+G AA      AV SGL D+ + VGV+KMT+   S + 
Sbjct: 64  PIVAEYSGLTGKVPLRVEAMCATGLAAALSAYTAVASGLVDIAMAVGVDKMTEVDTSTSL 123

Query: 123 RYLAYASDAEWEL-FHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYAM 181
                  + +WE  F+G +F    AL    +M  +G TEE +AL +V AH  G+ NP A 
Sbjct: 124 AIGGRGGNYQWEYHFYGTTFPTYYALYATRHMAVFGTTEEQMALVSVKAHKYGSMNPKAH 183

Query: 182 FKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMG 241
           F++P+TVE V+KS  I+ P+KL D+ P+ DG+A  +    EK KEL I    W  I G+G
Sbjct: 184 FQKPVTVEEVLKSRVISWPIKLLDSCPISDGSATAVFASEEKVKELKIDSPVW--ITGIG 241

Query: 242 RAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALGV 301
            A D   +A R + +  KA ++AA +AY+MAKV P DI+   VHDAFT+   +  E LG 
Sbjct: 242 YANDYAYVARRGEWVGFKATQLAARQAYEMAKVTPNDIEVATVHDAFTIAEIMGYEDLGF 301

Query: 302 AEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGIQ 361
            EKG+G K  +EGQ    G   +   GGLKA+GHP+GATG+    E   Q+R EA    Q
Sbjct: 302 TEKGKGGKFIEEGQSEKGGKVGVNLFGGLKAKGHPLGATGLSMIYEITKQLRDEADKLQQ 361

Query: 362 VPDAEIGLTQNIGGTGSNITVTILRR 387
                IGL  N+GGTG    V ILRR
Sbjct: 362 PLKKYIGLVHNVGGTGHFAYVMILRR 387


>pir||A72689 probable nonspecific lipid-transfer protein APE0929 - Aeropyrum
           pernix (strain K1) >gi|5104598|dbj|BAA79913.1|
           (AP000060) 400aa long hypothetical nonspecific
           lipid-transfer protein [Aeropyrum pernix]
           Length = 400
           
 Score =  263 bits (666), Expect = 2e-69
 Identities = 160/390 (41%), Positives = 229/390 (58%), Gaps = 19/390 (4%)

Query: 6   IVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGID--KVDSLYVGNMASGSFVEQENLGA 63
           IVG G +  G     ++ +LA EA+ +A  +AGI+   VD + VGN  +G +  +     
Sbjct: 10  IVGTGHSKFGVRNDVNIAELAWEAMREAASEAGIELRDVDQVVVGN--AGGWSSEYLSSI 67

Query: 64  LIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDATR 123
           ++ ++AG+   P  +VEAACA+G AA++    A+ +G  D+VLVVGVEKM ++       
Sbjct: 68  VLLEYAGISGKPVYRVEAACATGSAAIKAAHDAIAAGEADLVLVVGVEKMNESPTPIVVE 127

Query: 124 YLAYASDAEWELFH-GVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYAMF 182
            +  A +  WE  + G++F    AL    YM+ +G TEEDL   AV  H + + NP A F
Sbjct: 128 MIGRAGNYFWEFENFGLTFPGYYALYATAYMSEFGATEEDLCRVAVKNHHHASMNPKAHF 187

Query: 183 KRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMGR 242
            R IT+E  ++S Y+A PLKL+D+SP+ DGAAAV++   + A++L    D  V I  +G 
Sbjct: 188 PRAITLEQCLQSRYVAWPLKLYDSSPITDGAAAVVMASEDLARKL---TDSPVWIHSIGM 244

Query: 243 AIDTINLANREDLLTLKAAKIAAEKAYKMAKVEP----KDIDFFEVHDAFTVMAALSLEA 298
           A DT NL+ R D L  +A+++AAE+A+K   +E     K  DF  VHDAFT+   L+ EA
Sbjct: 245 ASDTSNLSKRPDFLVHRASRLAAERAFKKLGIEIEGSYKHFDFANVHDAFTIAEILAYEA 304

Query: 299 LGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPN 358
           +G A+ GEG KL +E Q  + G  P+   GGLKA+GHP+GATGV   VE V Q++G    
Sbjct: 305 MGFAKLGEGYKLVREEQTYVGGLIPVNLDGGLKAKGHPIGATGVSMAVEHVRQLQGRVEK 364

Query: 359 GIQVPDAEI----GLTQNIGGTGSNITVTI 384
           G Q   AEI     L  N+GGTG    VT+
Sbjct: 365 GRQ---AEIKRGRSLAHNVGGTGHYAFVTV 391


>gb|AAK42980.1| Acetyl-CoA c-acetyltransferase (acetoacetyl-CoA thiolase) (acaB-9)
           [Sulfolobus solfataricus]
           Length = 395
           
 Score =  263 bits (665), Expect = 3e-69
 Identities = 158/392 (40%), Positives = 226/392 (57%), Gaps = 13/392 (3%)

Query: 1   MEKPIIVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVDSLY--VGNMASGSFVEQ 58
           M    I+G G T  G     +L++LA EA+ +A+++A ID+ +  Y  VGN+  G++  +
Sbjct: 1   MRNVAIIGTGHTKFGVRTDVNLQELAWEAVKQALEEANIDQNEIQYFVVGNV--GNWSSE 58

Query: 59  ENLGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWP 118
           E    ++ ++  L     ++VEAAC++G AA+++   A+ SG  D+ LVVGVE+M  A  
Sbjct: 59  ELPAVIVGEYCNLTPKGTMRVEAACSTGSAAIRDAYLAIKSGEADIALVVGVEQMHQAPN 118

Query: 119 SDATRYLAYASDAEWELFH-GVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKN 177
                 +  A    WE  + G++F    AL    YM  YG  EEDL   A+  H  GAKN
Sbjct: 119 PQVVELIGRAGGYFWEFENFGLTFPGYYALHASAYMAKYGMKEEDLGKIAIKNHYYGAKN 178

Query: 178 PYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEI 237
           PYA F++ IT+E  +KS  +A PLKL D+SP+ DGAAA+++   E AK++    D  V I
Sbjct: 179 PYAQFQKEITMEEYLKSKPVAYPLKLLDSSPITDGAAAIVLASEEVAKKI---TDSPVWI 235

Query: 238 AGMGRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVE----PKDIDFFEVHDAFTVMAA 293
              G A  T NL+ R D   ++AA IAA++AYK A++E     K+ D  +VHD FT+   
Sbjct: 236 VSQGVASGTANLSRRTDFTHIEAAHIAAQQAYKRARIEFDNAWKNFDVADVHDCFTIAEI 295

Query: 294 LSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIR 353
           ++ E LG A++GEG  LA+E Q  I G  P+   GGLKA+GHP+GATGV   V    Q+ 
Sbjct: 296 MAYEDLGFAKRGEGYLLAREEQTYIGGKIPVNVDGGLKAKGHPIGATGVSMAVSITRQLL 355

Query: 354 GEAPNGIQVPDAE-IGLTQNIGGTGSNITVTI 384
             A  G QV     +G+T N+GGTG    VTI
Sbjct: 356 YRAHKGTQVEVRNGMGITHNVGGTGHYAYVTI 387


>gb|AAG19170.1| (AE005014) 3-ketoacyl-CoA thiolase; AcaB1 [Halobacterium sp. NRC-1]
           Length = 395
           
 Score =  256 bits (648), Expect = 2e-67
 Identities = 147/385 (38%), Positives = 218/385 (56%), Gaps = 5/385 (1%)

Query: 6   IVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVD--SLYVGNMASGSFVEQENLGA 63
           + GVG+T  G H   + RDL  EA L A+DDAG+ + D  +++ GN        Q + G 
Sbjct: 6   VAGVGLTHFGVHPERTSRDLFAEAGLAALDDAGVAREDVAAVHYGNFMGELSEHQGHQGP 65

Query: 64  LIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDATR 123
           L+A+  GL ++PA + E+ACAS G A++   + V +G  DVV+V G E+M +   +++T 
Sbjct: 66  LVAEALGL-DVPATRYESACASSGVALRRAVRDVRNGEADVVVVGGAERMNNLETAESTD 124

Query: 124 YLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYAMFK 183
            LA A+D  +E+  G++F    AL+   Y   +G + EDLA  AV  HAN   N  A ++
Sbjct: 125 ALAIAADGLYEVRAGMTFPGAYALMAASYFEQFGGSREDLAHIAVKNHANAVDNDRAQYQ 184

Query: 184 RPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMGRA 243
           + ITV   ++SP +A+PL L+DA PV DGA+A+++     A    +     V + G G+ 
Sbjct: 185 QAITVADALESPPVAEPLHLYDACPVTDGASALVLVSESYADTHDVSAP--VAVTGTGQG 242

Query: 244 IDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALGVAE 303
            D + L +R+++ T  AA  AA +AY  A V   D+D  EVHD FT+   ++ E+LG  +
Sbjct: 243 GDKMALQDRQNMATSPAATDAATEAYADAGVSADDVDVAEVHDCFTIAEVMATESLGFFD 302

Query: 304 KGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGIQVP 363
            G G   A+EG    DG  P+   GGLKA+GHPVGATG  Q  E    +RG+  N   V 
Sbjct: 303 PGAGITAAREGVTTKDGRLPVNLSGGLKAKGHPVGATGTSQVAELTRLLRGDHVNSEHVA 362

Query: 364 DAEIGLTQNIGGTGSNITVTILRRV 388
           DA+  +  N GGT ++  V +L  V
Sbjct: 363 DAQTAVAHNAGGTVASAVVHVLETV 387


>gb|AAG19361.1| (AE005031) 3-ketoacyl-CoA thiolase; AcaB2 [Halobacterium sp. NRC-1]
           Length = 383
           
 Score =  256 bits (648), Expect = 2e-67
 Identities = 159/392 (40%), Positives = 222/392 (56%), Gaps = 15/392 (3%)

Query: 1   MEKPIIVGVGMTPVGEH--WRTSLRDLAVEAILKAMDDAGID--KVDSLYVGNMASGSFV 56
           M++  I+G  MT  G+   W   L  L  EA   A+ DAG+D   VD LYV NMASG F 
Sbjct: 1   MDRVAIIGASMTAFGDRDAW---LLALLAEAGDAALTDAGVDGDDVDHLYVSNMASGEFE 57

Query: 57  EQENL-GALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTD 115
            Q  +  AL  D A +    A +++   +SGGA +    ++V SG  D+ L+VG EKMT 
Sbjct: 58  GQTGVPNALAHDLAAMPAYTA-RIDQTSSSGGAGIYAAWQSVASGASDLTLLVGGEKMTH 116

Query: 116 AWPSDATRYLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGA 175
               +AT  +A  +    E  HGV+  +   L  R Y+  Y    E L   AV  H NG 
Sbjct: 117 RTTGEATDVIASLTHPV-EYKHGVTLPSFAGLTARKYLAQYDAPRESLGKVAVKNHRNGL 175

Query: 176 KNPYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWV 235
            NP+A F++ + +ETV+ SP +ADPL+L+D  P+ DG+AA+++     A E     D +V
Sbjct: 176 DNPHAQFRKEVDLETVLDSPMVADPLRLYDFCPITDGSAALVLCPESVAAEY---TDDYV 232

Query: 236 EIAGMGRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALS 295
            I+G+  A DT  +  R+D  T++    +AE+AY+MA   P DID  E+HD FT++  L 
Sbjct: 233 VISGVAGATDTHVVHERDDPTTMRGVVESAEQAYEMAGRGPDDIDVAELHDMFTILEFLQ 292

Query: 296 LEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGE 355
            E LG  EKG G K  ++G    DGD PI T GGLK++GHP+GA+GV Q  E   Q+ G 
Sbjct: 293 SEDLGFFEKGAGWKAVRDGVTDRDGDLPINTSGGLKSKGHPLGASGVAQAYELYQQLLGT 352

Query: 356 APNGIQVPDAEIGLTQNIGGTGSNITVTILRR 387
           A  G +  DAE+GL  N+GG G+ +T TIL +
Sbjct: 353 A--GDRQVDAEVGLACNVGGFGNCVTTTILEQ 382


>emb|CAC11179.1| (AL445063) probable acetyl CoA synthase [Thermoplasma acidophilum]
           Length = 391
           
 Score =  252 bits (638), Expect = 4e-66
 Identities = 155/394 (39%), Positives = 227/394 (57%), Gaps = 17/394 (4%)

Query: 1   MEKPIIVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDK--VDSLYVGNMASGSFVEQ 58
           M +  I+G G++  G+    S+ DL  EA  +A+  +G+DK  +D + V NM   S    
Sbjct: 2   MNRVAIIGYGISKFGKRTDASMYDLIWEAGSEAIRSSGVDKKDIDYMVVSNMGMWS---S 58

Query: 59  ENLGALIA-DWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAW 117
           E L A++A +  G+ N    +VEAACASG +A+     A+ SG   + + +G+EKM +  
Sbjct: 59  EELPAVVAGEVLGIRNAGLHRVEAACASGSSAIASAYDAIRSGRSKIAIALGIEKMNEVE 118

Query: 118 PSDATRYLAYASDAEWEL-FHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAK 176
              A   +  A +  WE  F G++F    AL    Y+N Y   EEDLAL +V  H     
Sbjct: 119 SETAIELIGRAGNFLWEYEFFGLTFPGYYALYATAYLNRYSGKEEDLALVSVKNHHYAHL 178

Query: 177 NPYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVE 236
           NP A F   ITV+ VMKS YIA PLKL+D+SP+ DG+AAVI+   + AK+     D  V 
Sbjct: 179 NPIAHFSNEITVDDVMKSRYIASPLKLYDSSPITDGSAAVILASEDVAKQY---TDTPVW 235

Query: 237 IAGMGRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEP----KDIDFFEVHDAFTVMA 292
           I  +G  + T NL+ R+D + ++AA+ AA KAY+MAK++     + +D  +VHD F++  
Sbjct: 236 IDAIGSNLGTANLSKRDDFVHIEAAREAAAKAYRMAKIDAAKPYRYLDGADVHDCFSIAE 295

Query: 293 ALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQI 352
            L+ E LG AE+G+G  + ++G+  I G  P+   GGL ++GHP+GATGV   VE+  Q+
Sbjct: 296 VLAYEDLGFAERGKGLDMLRDGETYIGGKIPVNVDGGLISKGHPIGATGVAMAVEASKQL 355

Query: 353 RGEAPNGIQVPDAEIG--LTQNIGGTGSNITVTI 384
             +A  G Q+ D + G  LT N+GGTG    VTI
Sbjct: 356 LRKAEPGRQI-DVKNGKFLTHNVGGTGHYAYVTI 388


>gi|11498889 3-ketoacyl-CoA thiolase (acaB-11) [Archaeoglobus fulgidus]
           >gi|7450464|pir||B69411 3-ketoacyl-CoA thiolase
           (acaB-11) homolog - Archaeoglobus fulgidus
           >gi|2649290|gb|AAB89956.1| (AE001015) 3-ketoacyl-CoA
           thiolase (acaB-11) [Archaeoglobus fulgidus]
           Length = 392
           
 Score =  247 bits (623), Expect = 2e-64
 Identities = 157/394 (39%), Positives = 214/394 (53%), Gaps = 16/394 (4%)

Query: 6   IVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVD--SLYVGNMASGSFVEQENLGA 63
           ++GVGMT  G+H   SL DL  EA  +A +++ I+  D  +LY GN          NL  
Sbjct: 3   VLGVGMTKFGKHPDKSLVDLFAEAFYEAFEESNIELKDIQALYYGNFVGEMTDGSGNLSG 62

Query: 64  LIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDATR 123
            +AD  GL  IPA++ E ACAS   A +E  +AV +G  D+V V G E++  A     TR
Sbjct: 63  FMADEIGLRGIPAIRYEGACASSSVAFREAVRAVAAGYYDIVAVGGSERLYTAGTEIGTR 122

Query: 124 YLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDL----ALFAVNAHANGAKNPY 179
            LA A D  +E+  G++F  + AL  R Y   Y    E+L    A+ +V  H  GA NP 
Sbjct: 123 ALATAVDGVYEITAGLTFPGVFALAARLYSKKYEIPLEELREMMAMVSVKNHRYGAINPK 182

Query: 180 AMFKRPI---TVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVE 236
           A F   +    VE V+ S  I+ PL L D  P+ DG +A II   + A+EL    D  V 
Sbjct: 183 AQFYGKLGDLKVEDVLNSRMISSPLTLLDCCPMTDGGSAAIIAAADLAEEL---VDTPVY 239

Query: 237 IAGMGRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSL 296
           + G G++        +ED++     + A+E A+K A + PKDIDF EVHD FT+   ++L
Sbjct: 240 VRGTGQSSAGGLFRQKEDIIRAIPRRKASEMAFKEANMTPKDIDFVEVHDCFTIAEIIAL 299

Query: 297 EALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEA 356
           EA+G  E G+G    KEG  +IDGD P+   GGL  +GHPVGATGV Q    V Q+RGE 
Sbjct: 300 EAMGFFEYGQGCYAVKEGVTSIDGDLPVNPDGGLIGKGHPVGATGVSQVYSVVKQLRGEF 359

Query: 357 PNGIQVPDAEIGLTQNIG---GTGSNITVTILRR 387
                V DAE G+T  +G   GT  NI +++ RR
Sbjct: 360 KEN-PVKDAETGMTDTLGGDFGTLVNIILSVHRR 392


>gi|11497655 3-ketoacyl-CoA thiolase (acaB-2) [Archaeoglobus fulgidus]
           >gi|7450465|pir||B69254 3-ketoacyl-CoA thiolase (acaB-2)
           homolog - Archaeoglobus fulgidus
           >gi|2650617|gb|AAB91194.1| (AE001104) 3-ketoacyl-CoA
           thiolase (acaB-2) [Archaeoglobus fulgidus]
           Length = 417
           
 Score =  244 bits (617), Expect = 1e-63
 Identities = 153/392 (39%), Positives = 220/392 (56%), Gaps = 15/392 (3%)

Query: 1   MEKPIIVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVDSLYVGNMASGSFVEQEN 60
           M +  ++G G+T  G HW     DL VEA  +A+ DA ++  D   V  +  G+F     
Sbjct: 35  MREVAVIGCGVTKFGHHWEKDHEDLLVEATYEAIADANVELKD---VEAVWCGTFYPSTG 91

Query: 61  L-GALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPS 119
           + G + +D       P  +VE  CA+G   ++  A AV SG  D+V+  GVEK+ DA   
Sbjct: 92  ISGNVFSDTLKFFGKPISRVENYCATGMDNIRNAAFAVASGAYDLVIAAGVEKLMDA--- 148

Query: 120 DATRYLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPY 179
             +R L             VS  A+ A+        +G+T EDLA+ AV  H NGA++P 
Sbjct: 149 -GSRGLPPIEGIFSVAMPYVSAPAMFAMAANRAFKEWGWTREDLAMVAVKNHYNGARHPK 207

Query: 180 AMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAG 239
           A F+  +TVE V+K+P +A PL ++D S V DGAAAV++T PE AKE  I  D +  I  
Sbjct: 208 AHFRSEVTVEKVLKAPMVAYPLGVYDCSAVSDGAAAVVLTRPEIAKE--IVGDDYAVIKA 265

Query: 240 MGRAIDTINLANR--EDLLTLKAAKIAAEKAYKMAKVE--PKDIDFFEVHDAFTVMAALS 295
           +G A++T++  +R  E  L+  A   AA+ AYKMA +E   K++DF  VHD FT+   ++
Sbjct: 266 VGMAVETMHPWHRPSESFLSFPATVKAAKMAYKMAGIENPRKELDFGIVHDCFTITELIN 325

Query: 296 LEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGE 355
            + + + + GEGA+L + G  AIDGD+PI   GGLK+ GHP+ A+GV    E   Q+ G+
Sbjct: 326 YQDMQLCKPGEGAELIRNGVTAIDGDFPINPDGGLKSFGHPIAASGVRMVAELTKQVLGK 385

Query: 356 APNGIQVPDAEIGLTQNIGGTGSNITVTILRR 387
           A  G+QV DAE G   N+GG  S  TV I+ R
Sbjct: 386 A-EGLQVKDAEAGFAHNLGGPYSVATVAIVSR 416


>gb|AAK42810.1| Acetyl-CoA c-acetyltransferase (acetoacetyl-CoA thiolase) (acaB-8)
           [Sulfolobus solfataricus]
           Length = 376
           
 Score =  234 bits (591), Expect = 1e-60
 Identities = 141/379 (37%), Positives = 217/379 (57%), Gaps = 11/379 (2%)

Query: 6   IVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVDSLYVGNMASGSFVEQENLGALI 65
           I+   +T  G+  + SL +LA E  L  +   G  ++D + V N  SG F     +  LI
Sbjct: 4   IIDASITRFGKR-KESLLELAGEVALPLI---GKYEIDFVVVSNSYSGEFNSLSGINNLI 59

Query: 66  ADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDATRYL 125
             +  +  +P+++V+    SGG+A+      + S +   VLV+GVEKM++      T  +
Sbjct: 60  TTYLSVDKVPSIRVDNTSGSGGSAILVAKSLLDSKITKTVLVLGVEKMSEKNTKQVTSVI 119

Query: 126 AYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYAMFKRP 185
           A     E E   G++  +L  L+ + YM  Y  + E  AL AV  H NG+ NP+A  ++ 
Sbjct: 120 ASLLSPE-EKIVGLTLPSLAGLMTKEYMRRYNASREAFALVAVKNHYNGSLNPFAHIQKV 178

Query: 186 ITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMGRAID 245
           +++E V+ SP IADPL L++ +P+ DGA+A+++   E A        K V I GMG + D
Sbjct: 179 VSLEEVLNSPIIADPLTLYEFTPISDGASAIVMVRDEDAYSF---TKKPVFIKGMGASSD 235

Query: 246 TINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALGVAEKG 305
           T  L+ RED+LT+ A +IA   A KMAKV+   +DF E+HD  TV+  +  E LG+ +KG
Sbjct: 236 TSYLSEREDILTMNAVRIAGLTARKMAKVDK--VDFAELHDMATVLEIVEAEELGLLKKG 293

Query: 306 EGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGIQVPDA 365
           EG K   +    I+G+ PI T GGL ++GHP+GA+G+ Q VE+ LQIR +A    QV +A
Sbjct: 294 EGWKAYYDDYTKINGEMPINTSGGLNSKGHPIGASGIAQAVEAFLQIRNQA-GSRQVRNA 352

Query: 366 EIGLTQNIGGTGSNITVTI 384
            +GL+ ++ G G++ TV I
Sbjct: 353 RVGLSLSMAGFGNSATVII 371


>gi|11497639 3-ketoacyl-CoA thiolase (acaB-1) [Archaeoglobus fulgidus]
           >gi|7450463|pir||B69252 3-ketoacyl-CoA thiolase (acaB-1)
           homolog - Archaeoglobus fulgidus
           >gi|2650632|gb|AAB91208.1| (AE001105) 3-ketoacyl-CoA
           thiolase (acaB-1) [Archaeoglobus fulgidus]
           Length = 391
           
 Score =  222 bits (561), Expect = 4e-57
 Identities = 141/375 (37%), Positives = 206/375 (54%), Gaps = 12/375 (3%)

Query: 7   VGVGMTPVGEHWRTSLRDLAVEAILKAMDDA-GIDK--VDSLYVGNMASGSFVEQENLGA 63
           +G G+T  G     S +DL VEA     DD   +DK  VDS ++G      +  Q ++  
Sbjct: 1   MGAGITNFGRR-EASWKDLVVEAGKALFDDVPNLDKKDVDSFFIGAAQPERWTYQTHVAP 59

Query: 64  LIADWAGLGNIPAV-KVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDAT 122
           L A+  G+     V + E+ACASG  A++    AV SGL DV +VVGVEKM   + + + 
Sbjct: 60  LAAELLGIKPRRVVARTESACASGQIAIRYAWLAVASGLSDVAVVVGVEKMNTKFMNLSQ 119

Query: 123 RYLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYAMF 182
             +    + E++   G++     A++ + +M+ YG TE+ +AL    A    + NPYA F
Sbjct: 120 TSMMNVGNREFDTAMGLTAPPYFAMVAQRHMHLYGTTEDQMALVREKAGEYASANPYAQF 179

Query: 183 KRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMGR 242
           ++ I+ E V+ S  +A PLKL D S + DGAAA++IT  EKA++       W+ + G+ R
Sbjct: 180 QKKISKEDVLNSRMVAPPLKLLDCSGITDGAAALLITTEEKARKF-TDTPVWI-LGGIQR 237

Query: 243 AI-DTIN-LANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALG 300
            + ++IN +    D L+L   +  A+  Y +  + P DID  EVHD FT+   +  E LG
Sbjct: 238 TMANSINEMGEMSDWLSL---RYLAKDVYDLFNITPDDIDVAEVHDCFTISEIMEYEELG 294

Query: 301 VAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGI 360
             +KGEG K  +EGQ  I G   +   GGL A GHP+GATGV Q  E V+Q RGE P+  
Sbjct: 295 FCKKGEGGKFIEEGQSYIGGKVAVNPSGGLLANGHPLGATGVRQAWEMVMQFRGEVPDKR 354

Query: 361 QVPDAEIGLTQNIGG 375
            V  AE+GL  N+ G
Sbjct: 355 YVSGAELGLAHNLSG 369


>pir||H72573 probable acetyl CoA synthase APE1872 - Aeropyrum pernix  (strain
           K1) >gi|5105564|dbj|BAA80877.1| (AP000062) 407aa long
           hypothetical acetyl CoA synthase [Aeropyrum pernix]
           Length = 407
           
 Score =  206 bits (519), Expect = 3e-52
 Identities = 133/381 (34%), Positives = 202/381 (52%), Gaps = 15/381 (3%)

Query: 6   IVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVDSLYVGNMASGSFVEQENLGALI 65
           +  VGM  VG H+ + + +LA EA+  A+ DAG   VD++ V +        Q ++ + I
Sbjct: 36  VKSVGMVKVGRHFSSGVEELAKEALESALSDAGWASVDAVVVSSFVYPRLSGQADIASYI 95

Query: 66  ADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDATRYL 125
               G G   A+ VEA  ASG AA    A+    G +  V+++GV+KM+DA  S     L
Sbjct: 96  VSSLGFGGATAITVEAGEASGLAAAVTAARLAAEGKK--VVLLGVDKMSDAPSSRVYSIL 153

Query: 126 AYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYAMFKRP 185
               + +W+  + +S  A++ L+   YM+ YG   + L+ +    H+N  +NPYAM +  
Sbjct: 154 KGVYNIDWDGVYPISHAAIHGLLADMYMSRYGVDRDTLSYWPALMHSNAKENPYAMLRFA 213

Query: 186 ITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMGRAID 245
           I  E V  +  +A PL + D   + DGAAAV ++      + G+   K VE A       
Sbjct: 214 IKPEAVKDAMPVALPLTMLDTFAMGDGAAAVTLS----RGDGGLAVLKAVEAAS-----G 264

Query: 246 TINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALGVAEKG 305
            +++++ +D LT+ A K A +KA  +A V   +ID  EVHD++T+   + LE+LG+AEKG
Sbjct: 265 PLSISHLDDPLTMPAVKEAWDKARSLAGV--NNIDVLEVHDSYTITGIIILESLGLAEKG 322

Query: 306 EGAKLAKEGQIAIDGDYP-IQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGIQVPD 364
             AK   EG     G+ P +   GGLKARGH  GATGVY   E  +Q+ G  P G+  P 
Sbjct: 323 TAAKRVAEGYFTPSGEGPTVNASGGLKARGHSGGATGVYMLGEIAMQLAGVFP-GVNAPG 381

Query: 365 AEIGLTQNIGGTGSNITVTIL 385
           A  G   +I G GS+  + +L
Sbjct: 382 ARTGAAVSINGHGSSAYIAVL 402


>gb|AAF89837.1|AF173961_3 (AF173961) putative benzoylsuccinyl-CoA thiolase [Thauera
           aromatica]
           Length = 385
           
 Score =  190 bits (478), Expect = 2e-47
 Identities = 125/377 (33%), Positives = 181/377 (47%), Gaps = 16/377 (4%)

Query: 3   KPIIVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDK---VDSLYVGNMASGSFVEQE 59
           K  I GVG T  G H       L   A L+A+  + ID+   V S YVGN  +G    Q 
Sbjct: 6   KVYIAGVGETKFGRH-EVDFDVLGRAAALEALKASNIDRPTMVQSAYVGNGTNGMVTGQ- 63

Query: 60  NLGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPS 119
               ++ D    G++P + VE+AC++GG A+    + V  GL DV + +G E  T    +
Sbjct: 64  ---TVLKDLGMCGHLPIINVESACSAGGMAIHLAVRDVALGLADVAIGIGCENHT-LHMA 119

Query: 120 DATRYLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPY 179
             T +    SD E    HG       A+  + YM   G T EDLA+  V    +   NPY
Sbjct: 120 QGTAFATAMSDIE--TVHGAVMTGKYAMRAQRYMYETGATAEDLAMITVKNRRHATNNPY 177

Query: 180 AMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAG 239
           A FK  I++E V+ S  +A PL L     + DGA AV++   E  K+LGI K     I  
Sbjct: 178 AWFKGEISIEEVVNSRVVASPLTLQQCCGIADGAGAVVVCSEEMVKKLGIKKP----IRV 233

Query: 240 MGRAIDTINLANR-EDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEA 298
            G  + +    NR  D+      +  A + Y+ + + P+D++  E+HDAFT+   L  E 
Sbjct: 234 AGSVVRSGPYHNRPRDITGDDITEETAHQLYEESGIGPEDVNIVELHDAFTIAELLYYEC 293

Query: 299 LGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPN 358
           LG+  KGEG K  ++G     G   +   GG+ + GHP+GA+G  Q   SV Q+R + P 
Sbjct: 294 LGLCPKGEGLKFLRDGNATHGGKCVVSPRGGMLSYGHPIGASGAAQIAASVKQMRNQCPG 353

Query: 359 GIQVPDAEIGLTQNIGG 375
               P   + +T   GG
Sbjct: 354 YQVEPVPRVAMTHVTGG 370


>emb|CAC11495.1| (AL445064) sterol carrier protein x/sterol carrier protein 2
           related protein [Thermoplasma acidophilum]
           Length = 437
           
 Score =  190 bits (477), Expect = 3e-47
 Identities = 127/382 (33%), Positives = 193/382 (50%), Gaps = 32/382 (8%)

Query: 33  AMDDAGIDKVD-SLYVGNMASGSFVEQENLGALIADWAGLGNIPAVKVEAACASGGAAVQ 91
           AM+DAG+   D    V +  S  F  Q   G ++ D+ GL   P+ ++E   A+GG A Q
Sbjct: 55  AMNDAGLTLADIDGSVASYFSDHFQRQLMSGIMVQDYLGLVPKPSKRIEGGGATGGLAFQ 114

Query: 92  EGAKAVLSGLEDVVLVVGVEKMTDAWPSDATRYLAYASDAEWELFHGVSFVALNALIMRH 151
            G + + SG  D V V G E M+         ++A ASD  ++   G  +    A++   
Sbjct: 115 AGYEEIASGRMDTVAVYGFETMSHVNTWKGNEFIALASDTNFDYPIGGFYTGYYAMMAVR 174

Query: 152 YMNTYGYTEEDLALFAVNAHANGAKNPYAMFKRPITVETVMKSPYIADPLKLFDASPVCD 211
           +M  +G T E LA  +V  H N   NPYA     +TVE V  +P ++ PL   D   + D
Sbjct: 175 HMYEFGTTVEQLAKVSVKNHGNALHNPYAQSPMKLTVEDVRNAPMVSYPLTRLDVCAMSD 234

Query: 212 GAAAVIITIPEKAKELGIPKDKWVEIAGMGRAIDTINLANR----------------EDL 255
           GAA  I+   +KA E+    D  V I G+G   D++ LA+R                +DL
Sbjct: 235 GAAVAILASEDKAFEI---TDHPVLIKGIGTGTDSMRLADRPFGDVPLLPNEKPSDYKDL 291

Query: 256 L-----TLKAAKIAAEKAYKMAKVEP--KDIDFFEVHDAFTVMAALSLEALGVAEKGEGA 308
                 + +A ++AA++AY+MA +     ++D  E+HDA+T     + E LG+ + GEG 
Sbjct: 292 KYPGVHSFRAGRMAAKEAYEMAGITDPLNELDLIELHDAYTSSEIQTYEDLGLCKYGEGG 351

Query: 309 KLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEA-----PNGIQVP 363
           +   EG+  + G  P+   GGL A GHPVGATG+ Q V    Q++         + +QVP
Sbjct: 352 QFIDEGKPELHGKIPVNPSGGLLAAGHPVGATGIMQAVFMFWQLQHTIKKHFHDDYLQVP 411

Query: 364 DAEIGLTQNIGGTGSNITVTIL 385
           +A+ GL  +  GTG+ +TVTI+
Sbjct: 412 NAKRGLIHSHAGTGTYVTVTIM 433


>gi|11497818 3-ketoacyl-CoA thiolase (acaB-6) [Archaeoglobus fulgidus]
           >gi|7450466|pir||B69275 3-ketoacyl-CoA thiolase (acaB-6)
           homolog - Archaeoglobus fulgidus
           >gi|2650440|gb|AAB91029.1| (AE001092) 3-ketoacyl-CoA
           thiolase (acaB-6) [Archaeoglobus fulgidus]
           Length = 380
           
 Score =  189 bits (476), Expect = 4e-47
 Identities = 135/385 (35%), Positives = 192/385 (49%), Gaps = 18/385 (4%)

Query: 6   IVGVGMTPVGEHWRTSLRD-----LAVEAILKAMDDAGIDKVDSLYVGNMASGSFVEQEN 60
           +VG G TP    +RT  +D     LA EAI  A+D AG++  D   V       F     
Sbjct: 5   VVGFGQTP----FRTKRKDKTHPELAFEAINAALDHAGLEMKDVEAVAYGCMDPFDGIYC 60

Query: 61  LGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSD 120
                A  AGL   P +K+     +G        + V SGL D+V+ V V+++ +    D
Sbjct: 61  PERWDATAAGLEK-PIMKISTGGTTGMTTALAAYEHVASGLFDLVMAVCVQRVGEC--VD 117

Query: 121 ATRYLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYA 180
           A   L  A D  +E   G+  + + +     YM  YG TEEDLA  +V  H N  KNPYA
Sbjct: 118 AQPVLNTAVDPIYERHSGLGAIHVASFQATAYMAKYGATEEDLAWVSVKDHKNALKNPYA 177

Query: 181 MFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGM 240
             K  ++VE V+KS  +  PLKL +  P  DGAAAVI    + A+++   +D    +   
Sbjct: 178 HIKMDVSVEGVLKSRVVCSPLKLLECCPRSDGAAAVIFASEDVARKI---RDNPAWVVAE 234

Query: 241 GRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALG 300
               D+  L +R       +  IA  + +K A +EP +ID  E++  FT+   L LEALG
Sbjct: 235 TTISDSYYLGDRPSFAEWDSLAIAGRRLFKAAGIEPDEIDVAELYSPFTIQEILELEALG 294

Query: 301 VAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGI 360
            A+KGEG   A+EG   +DGD+P    GG+    +P+GATG+ +  E+ LQ+  EA N  
Sbjct: 295 FAKKGEGKNFAREGVTFVDGDFPTNPSGGVLCT-NPIGATGLVRFGEAALQVMNEAKN-- 351

Query: 361 QVPDAEIGLTQNIGGTGSNITVTIL 385
           QV  AE+ L    GGT    T+ +L
Sbjct: 352 QVDGAEVALAHAWGGTLQFHTLALL 376


>emb|CAB55378.1| (AL117263) possible 3-ketoacyl-CoA thiolase [Leishmania major]
           Length = 441
           
 Score =  185 bits (464), Expect = 9e-46
 Identities = 130/401 (32%), Positives = 199/401 (49%), Gaps = 28/401 (6%)

Query: 15  GEHWRTSLRDLAVEAILKAMDDAGI----DKVDSLYVGNMASGSFVEQENLG-----ALI 65
           G+    +L ++    +   +++ G+    D VD + VGN     F  Q +LG     +L 
Sbjct: 42  GKKQNMTLEEILATTVQHTIENTGLNGKEDIVDQVVVGNFLGELFSSQGHLGPAAIGSLT 101

Query: 66  ADWAGLGNI----PAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDA 121
              AG  N     PA++VE ACASGG AV     A+ +G  D+ L VGVE  T A     
Sbjct: 102 YGQAGAKNPLMYKPAMRVEGACASGGLAVVSATNALKAGSADIALAVGVEVQTTATARVG 161

Query: 122 TRYLAYASDAEWEL-FHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYA 180
             YLA A+D + +      +F  L A  M++      +T ED A  A  A+ANG +NP A
Sbjct: 162 GDYLARAADYQRQRKLDDFTFPCLFAKRMKYIAEHNHFTMEDTARVAAKAYANGNRNPLA 221

Query: 181 -MFKRPITVETV----------MKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGI 229
            M  R ++ E            + +    + L++ D S V DG A V++   E  K++G+
Sbjct: 222 HMHTRKLSFEQCNGEDPSNVKFLGNETYKEYLRMTDCSQVSDGGAGVVLANEEGLKKMGL 281

Query: 230 -PKD-KWVEIAGMGRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDA 287
            P D + VEI  +  A+  +   + +D   +  ++ AA+KA  MA V+P D++  EVHD 
Sbjct: 282 SPNDSRLVEIKSIACAVSNL-YEDPDDACCMFTSRQAAQKALSMANVKPSDLNVAEVHDC 340

Query: 288 FTVMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVE 347
           FT+   L  EALG+AE G    L + G+  ++G  P+ T GGL + GHPVGATG+ Q +E
Sbjct: 341 FTIAEMLMYEALGIAEYGHAKDLIRNGETTLEGRIPVNTGGGLLSFGHPVGATGIKQVME 400

Query: 348 SVLQIRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTILRRV 388
              Q++G+           +G T N+GG        +L+ +
Sbjct: 401 VYRQMKGQCGAYQMKKIPALGATLNMGGDDKTAVSAVLQNI 441


>gb|AAK42246.1| Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) (acaB-3)
           [Sulfolobus solfataricus]
           Length = 409
           
 Score =  172 bits (432), Expect = 5e-42
 Identities = 129/385 (33%), Positives = 188/385 (48%), Gaps = 10/385 (2%)

Query: 6   IVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGID--KVDSLYVGNMASGSFVEQENLGA 63
           I+G G+T        + +++A EA  KA+D+AG++   +D + +G+ A  +F      G 
Sbjct: 30  IIGAGLTLFRRRLLETPQEIAWEAASKALDEAGLELKDIDCVVIGS-APDAFDGVNLKGE 88

Query: 64  LIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDATR 123
            ++  AG    P  +V    A+G      G   V SGL   VL V  EKM+ A P   + 
Sbjct: 89  YLSHGAGGIKKPVSRVYVGGATGVMTAITGWYHVASGLCQKVLAVAEEKMSPARPHPQSI 148

Query: 124 YLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYAMFK 183
           +  Y  D   E     + + + A+ M  YM TYG  +E++AL +V    N   NPYA   
Sbjct: 149 F-RYIWDPILEKPLNPNLIWIFAMEMHRYMATYGIKKEEIALVSVKNKRNAINNPYAQLG 207

Query: 184 RPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMGRA 243
             ITVE V+KS  +  P++L D SPV DG AA+++   + A+      D  V + G+G  
Sbjct: 208 SNITVEDVLKSEVLVWPVQLLDVSPVSDGGAAIVLASEDVARRY---TDTPVWVEGVGWT 264

Query: 244 IDTINLANREDLLTLKAAKIAAEKAYKMAKVE--PKDIDFFEVHDAFTVMAALSLEALGV 301
           +D      R DL   +  + AA  AYKMA +E   K+ID  E +D F       LEAL +
Sbjct: 265 LDNTEWPAR-DLAYARYVEFAARMAYKMAGIERPNKEIDVAEPYDPFDYKELHHLEALQL 323

Query: 302 AEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGIQ 361
           A++GE  KL KEG   IDGD P    GGL   G+P+ A G+ + +    Q++G A     
Sbjct: 324 AKRGEAPKLLKEGVFDIDGDIPSSPSGGLLGVGNPIAAAGLMKVISIYWQLKGIAGKMQV 383

Query: 362 VPDAEIGLTQNIGGTGSNITVTILR 386
                 G+ Q  G      TV +LR
Sbjct: 384 KRPVHTGVAQAWGDLMQAGTVIVLR 408


>pir||A39368 sterol carrier protein 2 precursor - rat >gi|202553|gb|AAA40622.1|
           (M62763) 60 kDa protein [Rattus norvegicus]
           Length = 547
           
 Score =  169 bits (425), Expect = 3e-41
 Identities = 129/404 (31%), Positives = 194/404 (47%), Gaps = 28/404 (6%)

Query: 1   MEKPIIVGVGMT----PVGEHWRTSLRDLAVEAILKAMDDAGI--DKVDSLYVGNMASGS 54
           + +  +VGVGMT    P GE+ R    DLA EA  KA+ DA I    V+   VG +   S
Sbjct: 11  LRRVFVVGVGMTKFMKPGGENSR-DYPDLAKEAGQKALADAQIPYSAVEQACVGYVYGES 69

Query: 55  FVEQENLGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMT 114
              Q      I    GL  IP + V   C++G  A+    + V  GL + VL +G EKM 
Sbjct: 70  TCGQR----AIYHSLGLTGIPIINVNNNCSTGSTALFMAQQLVQGGLANCVLALGFEKME 125

Query: 115 DAWPSDATRYLAYASDAEWELFHGVSFVALNALIM---------RHYMNTYGYTEEDLAL 165
               S  T+Y   ++  E  +   ++   ++A            + +M TYG   E  A 
Sbjct: 126 KG--SLGTKYSDRSNPLEKHIDVLINKYGMSACPFAPQLFGSAGKEHMETYGTKVEHFAK 183

Query: 166 FAVNAHANGAKNPYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAK 225
                H +   NPY+ F+   +++ +MKS  + D L +    P  DGAAA I++  E  +
Sbjct: 184 IGWKNHKHSVNNPYSQFQDEYSLDEIMKSRPVFDFLTVLQCCPTSDGAAAAIVSSEEFVQ 243

Query: 226 ELGIPKDKWVEIAGMGRAIDTINLANREDLLTLKA---AKIAAEKAYKMAKVEPKDIDFF 282
           + G+ + K VEI       D  +    + ++ +     +K AA K Y+ + + P D+D  
Sbjct: 244 KHGL-QSKAVEIVAQEMVTDMPSTFEEKSVIKMVGYDMSKEAARKCYEKSGLGPSDVDVI 302

Query: 283 EVHDAFTVMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGV 342
           E+HD F+    L+ EALG+  +G+G  L   G     G + I   GGL ++GHP+GATG+
Sbjct: 303 ELHDCFSTNELLTYEALGLCPEGQGGALVDRGDNTYGGKWVINPSGGLISKGHPLGATGL 362

Query: 343 YQTVESVLQIRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTILR 386
            Q  E   Q+RGEA    QVP A++ L  N+ G G    VT+ R
Sbjct: 363 AQCAELCWQLRGEAGKR-QVPGAKVALQHNL-GLGGAAVVTLYR 404


>pir||E70884 probable lipid-transfer protein - Mycobacterium tuberculosis
           (strain H37RV) >gi|2624312|emb|CAA15585.1| (AL008967)
           ltp1 [Mycobacterium tuberculosis]
           Length = 401
           
 Score =  168 bits (421), Expect = 1e-40
 Identities = 126/399 (31%), Positives = 186/399 (46%), Gaps = 24/399 (6%)

Query: 3   KPIIVGVGMTPVGEHWRTS---LRDLAVEAILKAMDDAGID--KVDSLYVGNMASGSFVE 57
           K  ++GVGMT   +  R       D+A E+  KA+ DAGID  +V+  YVG +   S   
Sbjct: 9   KVYVIGVGMTKFEKPGRREGWDYPDMARESGTKALRDAGIDYREVEQGYVGYVYGESTSG 68

Query: 58  QENLGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKM---- 113
           Q  L  L     G+  IP V V   C++G  A+  GA+A+  GL D VL +G EKM    
Sbjct: 69  QRALYEL-----GMTGIPIVNVNNNCSTGSTALYLGAQAIRGGLADCVLALGFEKMQPGA 123

Query: 114 ----TDAWPSDATRYLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVN 169
                D   S   R++   + AE + F       +     R +M  YG T E  A     
Sbjct: 124 LGGGADDRESPLGRHV--KALAEIDEFGFPVAPWMFGAAGREHMKKYGTTAEHFAKIGYK 181

Query: 170 AHANGAKNPYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGI 229
            H +   NPYA F+   T++ ++ S  I+DPL     SP  DG+AAV++   +      +
Sbjct: 182 NHKHSVNNPYAQFQDEYTLDDILASKMISDPLTKLQCSPTSDGSAAVVLASEDYLANHNL 241

Query: 230 PKDKWVEIAGMGRAIDTINL--ANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDA 287
              + VEI G     D  +    +  +++       AA++ Y+ + + PKD    E+HD 
Sbjct: 242 -AGRAVEIVGQAMTTDFASTFDGSARNIIGYDMTVQAAQRVYQQSGLGPKDFGVIELHDC 300

Query: 288 FTVMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVE 347
           F+    L  EALG+   GE  +L  + Q    G + +   GGL ++GHP+GATG+ Q  E
Sbjct: 301 FSANELLLYEALGLCGPGEAPELIDDNQTTYGGRWVVNPSGGLISKGHPLGATGLAQCAE 360

Query: 348 SVLQIRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTILR 386
              Q+RG A    QV +    L  NIG  G+ +     R
Sbjct: 361 LTWQLRGTA-EARQVDNVTAALQHNIGLGGAAVVTAYQR 398


>emb|CAA43061.1| (X60654) open reading frame for 58 kDa protein  containing the
           non-specific lipid transfer  protein [Rattus norvegicus]
           Length = 546
           
 Score =  168 bits (420), Expect = 1e-40
 Identities = 128/404 (31%), Positives = 193/404 (47%), Gaps = 28/404 (6%)

Query: 1   MEKPIIVGVGMT----PVGEHWRTSLRDLAVEAILKAMDDAGI--DKVDSLYVGNMASGS 54
           + +  +VGVGMT    P GE+ R    DLA EA  KA+ D  I    V+   VG +   S
Sbjct: 10  LRRVFVVGVGMTKFMKPGGENSR-DYPDLAKEAGQKALADRQIPYSAVEQACVGYVYGES 68

Query: 55  FVEQENLGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMT 114
              Q      I    GL  IP + V   C++G  A+    + V  GL + VL +G EKM 
Sbjct: 69  TCGQR----AIYHSLGLTGIPIINVNNNCSTGSTALFMAQQLVQGGLANCVLALGFEKME 124

Query: 115 DAWPSDATRYLAYASDAEWELFHGVSFVALNALIM---------RHYMNTYGYTEEDLAL 165
               S  T+Y   ++  E  +   ++   ++A            + +M TYG   E  A 
Sbjct: 125 KG--SLGTKYSDRSNPLEKHIDVLINKYGMSACPFAPQLFGSAGKEHMETYGTKVEHFAK 182

Query: 166 FAVNAHANGAKNPYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAK 225
                H +   NPY+ F+   +++ +MKS  + D L +    P  DGAAA I++  E  +
Sbjct: 183 IGWKNHKHSVNNPYSQFQDEYSLDEIMKSRPVFDFLTVLQCCPTSDGAAAAIVSSEEFVQ 242

Query: 226 ELGIPKDKWVEIAGMGRAIDTINLANREDLLTLKA---AKIAAEKAYKMAKVEPKDIDFF 282
           + G+ + K VEI       D  +    + ++ +     +K AA K Y+ + + P D+D  
Sbjct: 243 KHGL-QSKAVEIVAQEMVTDMPSTFEEKSVIKMVGYDMSKEAARKCYEKSGLGPSDVDVI 301

Query: 283 EVHDAFTVMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGV 342
           E+HD F+    L+ EALG+  +G+G  L   G     G + I   GGL ++GHP+GATG+
Sbjct: 302 ELHDCFSTNELLTYEALGLCPEGQGGALVDRGDNTYGGKWVINPSGGLISKGHPLGATGL 361

Query: 343 YQTVESVLQIRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTILR 386
            Q  E   Q+RGEA    QVP A++ L  N+ G G    VT+ R
Sbjct: 362 AQCAELCWQLRGEAGKR-QVPGAKVALQHNL-GLGGAAVVTLYR 403


>gb|AAB27044.1| 3-oxoacyl-CoA thiolase homolog {N-terminal} [rats, Peptide Partial,
           405 aa]
           Length = 405
           
 Score =  168 bits (420), Expect = 1e-40
 Identities = 128/404 (31%), Positives = 193/404 (47%), Gaps = 28/404 (6%)

Query: 1   MEKPIIVGVGMT----PVGEHWRTSLRDLAVEAILKAMDDAGI--DKVDSLYVGNMASGS 54
           + +  +VGVGMT    P GE+ R    DLA EA  KA+ D  I    V+   VG +   S
Sbjct: 10  LRRVFVVGVGMTKFMKPGGENSR-DYPDLAKEAGQKALADRQIPYSAVEQACVGYVYGES 68

Query: 55  FVEQENLGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMT 114
              Q      I    GL  IP + V   C++G  A+    + V  GL + VL +G EKM 
Sbjct: 69  TCGQR----AIYHSLGLTGIPIINVNNNCSTGSTALFMAQQLVQGGLANCVLALGFEKME 124

Query: 115 DAWPSDATRYLAYASDAEWELFHGVSFVALNALIM---------RHYMNTYGYTEEDLAL 165
               S  T+Y   ++  E  +   ++   ++A            + +M TYG   E  A 
Sbjct: 125 KG--SLGTKYSDRSNPLEKHIDVLINKYGMSACPFAPQLFGSAGKEHMETYGTKVEHFAK 182

Query: 166 FAVNAHANGAKNPYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAK 225
                H +   NPY+ F+   +++ +MKS  + D L +    P  DGAAA I++  E  +
Sbjct: 183 IGWKNHKHSVNNPYSQFQDEYSLDEIMKSRPVFDFLTVLQCCPTSDGAAAAIVSSEEFVQ 242

Query: 226 ELGIPKDKWVEIAGMGRAIDTINLANREDLLTLKA---AKIAAEKAYKMAKVEPKDIDFF 282
           + G+ + K VEI       D  +    + ++ +     +K AA K Y+ + + P D+D  
Sbjct: 243 KHGL-QSKAVEIVAQEMVTDMPSTFEEKSVIKMVGYDMSKEAARKCYEKSGLGPSDVDVI 301

Query: 283 EVHDAFTVMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGV 342
           E+HD F+    L+ EALG+  +G+G  L   G     G + I   GGL ++GHP+GATG+
Sbjct: 302 ELHDCFSTNELLTYEALGLCPEGQGGALVDRGDNTYGGKWVINPSGGLISKGHPLGATGL 361

Query: 343 YQTVESVLQIRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTILR 386
            Q  E   Q+RGEA    QVP A++ L  N+ G G    VT+ R
Sbjct: 362 AQCAELCWQLRGEAGKR-QVPGAKVALQHNL-GLGGAAVVTLYR 403


>sp|P11915|NLTP_RAT NONSPECIFIC LIPID-TRANSFER PROTEIN PRECURSOR (NSL-TP) (STEROL
           CARRIER PROTEIN 2) (SCP-2) (STEROL CARRIER PROTEIN X)
           (SCP-X) (SCPX)
           Length = 547
           
 Score =  167 bits (419), Expect = 2e-40
 Identities = 128/404 (31%), Positives = 193/404 (47%), Gaps = 28/404 (6%)

Query: 1   MEKPIIVGVGMT----PVGEHWRTSLRDLAVEAILKAMDDAGI--DKVDSLYVGNMASGS 54
           + +  +VGVGMT    P GE+ R    DLA EA  KA+ D  I    V+   VG +   S
Sbjct: 11  LPRVFVVGVGMTKFMKPGGENSR-DYPDLAKEAGQKALADRQIPYSAVEQACVGYVYGES 69

Query: 55  FVEQENLGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMT 114
              Q      I    GL  IP + V   C++G  A+    + V  GL + VL +G EKM 
Sbjct: 70  TCGQR----AIYHSLGLTGIPIINVNNNCSTGSTALFMAQQLVQGGLANCVLALGFEKME 125

Query: 115 DAWPSDATRYLAYASDAEWELFHGVSFVALNALIM---------RHYMNTYGYTEEDLAL 165
               S  T+Y   ++  E  +   ++   ++A            + +M TYG   E  A 
Sbjct: 126 KG--SLGTKYSDRSNPLEKHIDVLINKYGMSACPFAPQLFGSAGKEHMETYGTKVEHFAK 183

Query: 166 FAVNAHANGAKNPYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAK 225
                H +   NPY+ F+   +++ +MKS  + D L +    P  DGAAA I++  E  +
Sbjct: 184 IGWKNHKHSVNNPYSQFQDEYSLDEIMKSRPVFDFLTVLQCCPTSDGAAAAIVSSEEFVQ 243

Query: 226 ELGIPKDKWVEIAGMGRAIDTINLANREDLLTLKA---AKIAAEKAYKMAKVEPKDIDFF 282
           + G+ + K VEI       D  +    + ++ +     +K AA K Y+ + + P D+D  
Sbjct: 244 KHGL-QSKAVEIVAQEMVTDMPSTFEEKSVIKMVGYDMSKEAARKCYEKSGLGPSDVDVI 302

Query: 283 EVHDAFTVMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGV 342
           E+HD F+    L+ EALG+  +G+G  L   G     G + I   GGL ++GHP+GATG+
Sbjct: 303 ELHDCFSTNELLTYEALGLCPEGQGGALVDRGDNTYGGKWVINPSGGLISKGHPLGATGL 362

Query: 343 YQTVESVLQIRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTILR 386
            Q  E   Q+RGEA    QVP A++ L  N+ G G    VT+ R
Sbjct: 363 AQCAELCWQLRGEAGKR-QVPGAKVALQHNL-GLGGAAVVTLYR 404


>pir||A70559 hypothetical protein Rv1627c - Mycobacterium tuberculosis  (strain
           H37RV) >gi|2113911|emb|CAB08880.1| (Z95554) hypothetical
           protein Rv1627c [Mycobacterium tuberculosis]
           Length = 402
           
 Score =  167 bits (419), Expect = 2e-40
 Identities = 132/417 (31%), Positives = 193/417 (45%), Gaps = 59/417 (14%)

Query: 2   EKPIIVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGID-----------KVDSLYVGNM 50
           E   I+G GM P G+ W     +  V A   A+ DAG+D            + + Y G +
Sbjct: 7   EPVYILGAGMHPWGK-WGNDFTEYGVVAARAALRDAGVDWRHVQLVAGADTIRNGYPGFV 65

Query: 51  ASGSFVEQENLGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGV 110
           A  +F ++  LG     W G   +P     AACASG  A+Q     +L+G  DV LV+G 
Sbjct: 66  AGATFAQK--LG-----WTG---VPVSSSYAACASGSQALQSARAQILAGFCDVALVIGA 115

Query: 111 EKMTDAW--PSDATRYLAYASDAEWELFH--GVSFVALNALIMRHYMNTYGYTEEDLALF 166
           +     +  P    R      D +W+ FH  G +     AL+ R  M+ YG T ED A  
Sbjct: 116 DTTPKGFFAPVGGER----KGDPDWQRFHLIGATNTVYFALLARRRMDLYGATVEDFAQV 171

Query: 167 AVNAHANGAKNPYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPE-KAK 225
            V    +G  NP A +++  +++ V+ SP ++DPL+L D     DGAAA+I+       K
Sbjct: 172 KVKNSRHGLDNPNARYRKENSIDDVLASPVVSDPLRLLDICATSDGAAALIVASKSFTEK 231

Query: 226 ELGIPKDKWVEIAGMG--RAIDTI------NLANREDLLTLKAAKIAA----------EK 267
            LG        +AG+   RAI T+      +L    D+ T   A + A          + 
Sbjct: 232 HLG-------SVAGVPSVRAISTVTPKYPQHLPELPDIATDSTAAVPAPERVFKDQILDA 284

Query: 268 AYKMAKVEPKDIDFFEVHDAFTVMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTM 327
           AY  A + P+D+   EV+D  T +     E LG+  KGE   L + G   + G  P+   
Sbjct: 285 AYAEAGIGPEDLSLAEVYDLSTALELDWYEHLGLCPKGEAEALLRSGATTLGGRVPVNPS 344

Query: 328 GGLKARGHPVGATGVYQTVESVLQIRGEAPNGIQVPDAEIGLTQNIG--GTGSNITV 382
           GGL   G  + A  + Q  E   Q+RG+A  G QV DA++G+T N G  G GS++ V
Sbjct: 345 GGLACFGEAIPAQAIAQVCELTWQLRGQA-TGRQVADAKVGVTANQGLFGHGSSVIV 400


>gb|AAA42122.1| (M57453) sterol carrier protein-x [Rattus norvegicus]
           Length = 547
           
 Score =  167 bits (418), Expect = 2e-40
 Identities = 128/404 (31%), Positives = 192/404 (46%), Gaps = 28/404 (6%)

Query: 1   MEKPIIVGVGMT----PVGEHWRTSLRDLAVEAILKAMDDAGI--DKVDSLYVGNMASGS 54
           + +  +VGVGMT    P GE+ R    DLA EA  KA+ D  I    V+   VG +   S
Sbjct: 11  LPRVFVVGVGMTKFMKPGGENSR-DYPDLAKEAGQKALADRQIPYSAVEQACVGYVYGES 69

Query: 55  FVEQENLGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMT 114
              Q      I    GL  IP + V   C++G  A+    + V  GL + VL +G EKM 
Sbjct: 70  TCGQR----AIYHSLGLTGIPIINVNNNCSTGSTALFMAQQLVQGGLANCVLALGFEKME 125

Query: 115 DAWPSDATRYLAYASDAEWELFHGVSFVALNALIM---------RHYMNTYGYTEEDLAL 165
               S  T+Y   ++  E  +   ++   ++A            + +M TYG   E  A 
Sbjct: 126 KG--SLGTKYSDRSNPLEKHIDVLINKYGMSACPFAPQLFGSAGKEHMETYGTKVEHFAK 183

Query: 166 FAVNAHANGAKNPYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAK 225
                H +   NPY+ F+   +++ +MKS  + D L +    P  DGAAA I++  E  +
Sbjct: 184 IGWKNHKHSVNNPYSQFQDEYSLDEIMKSRPVFDFLTVLQCCPTSDGAAAAIVSSEEFVQ 243

Query: 226 ELGIPKDKWVEIAGMGRAIDTINLANREDLLTLKA---AKIAAEKAYKMAKVEPKDIDFF 282
           + G+ + K VEI       D       + ++ +     +K AA K Y+ + + P D+D  
Sbjct: 244 KHGL-QSKAVEIVAQEMVTDMPTTFEEKSVIKMVGYDMSKEAARKCYEKSGLGPSDVDVI 302

Query: 283 EVHDAFTVMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGV 342
           E+HD F+    L+ EALG+  +G+G  L   G     G + I   GGL ++GHP+GATG+
Sbjct: 303 ELHDCFSTNELLTYEALGLCPEGQGGALVDRGDNTYGGKWVINPSGGLISKGHPLGATGL 362

Query: 343 YQTVESVLQIRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTILR 386
            Q  E   Q+RGEA    QVP A++ L  N+ G G    VT+ R
Sbjct: 363 AQCAELCWQLRGEAGKR-QVPGAKVALQHNL-GLGGAAVVTLYR 404


>sp|P32020|NLTP_MOUSE NONSPECIFIC LIPID-TRANSFER PROTEIN PRECURSOR (NSL-TP) (STEROL
           CARRIER PROTEIN 2) (SCP-2) (STEROL CARRIER PROTEIN X)
           (SCP-X) (SCPX) >gi|420230|pir||JU0157 sterol carrier
           protein x - mouse >gi|293794|gb|AAA40098.1| (M91458)
           sterol-carrier protein X [Mus musculus]
           Length = 547
           
 Score =  165 bits (413), Expect = 9e-40
 Identities = 124/402 (30%), Positives = 191/402 (46%), Gaps = 24/402 (5%)

Query: 1   MEKPIIVGVGMT----PVGEHWRTSLRDLAVEAILKAMDDAGI--DKVDSLYVGNMASGS 54
           + +  +VGVGMT    P GE+ R    D+A EA  KA++DA I    V+   VG +   S
Sbjct: 11  LRRVFVVGVGMTKFMKPGGENSR-DYPDMAKEAGQKALEDAQIPYSAVEQACVGYVYGDS 69

Query: 55  FVEQENLGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMT 114
              Q      I    GL  IP + V   C++G  A+    + +  GL + VL +G EKM 
Sbjct: 70  TSGQR----AIYHSLGLTGIPIINVNNNCSTGSTALFMAHQLIQGGLANCVLALGFEKME 125

Query: 115 DAWPSDATRYLAYASDAEWELF---HGVSFVALNALIM----RHYMNTYGYTEEDLALFA 167
                         +D   E+    +G+S   +   +     + +M  YG   E  A   
Sbjct: 126 RGSIGTKFSDRTTPTDKHIEVLIDKYGLSAHPITPQMFGYAGKEHMEKYGTKVEHFAKIG 185

Query: 168 VNAHANGAKNPYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKEL 227
              H +   N Y+ F+   ++E VMKS  + D L +    P  DGA A I++  E  ++ 
Sbjct: 186 WKNHKHSVNNTYSQFQDEYSLEEVMKSKPVFDFLTILQCCPTSDGACAAILSSEEFVQQY 245

Query: 228 GIPKDKWVEIAGMGRAIDTINLANREDLLTLKA---AKIAAEKAYKMAKVEPKDIDFFEV 284
           G+ + K VEI       D  +    + ++ +     +K AA + Y+ + + P D+D  E+
Sbjct: 246 GL-QSKAVEIVAQEMMTDLPSTFEEKSIIKVVGYDMSKEAARRCYEKSGLTPNDVDVIEL 304

Query: 285 HDAFTVMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQ 344
           HD F+V   ++ EALG+  +G+G  L   G     G + I   GGL ++GHP+GATG+ Q
Sbjct: 305 HDCFSVNELITYEALGLCPEGQGGTLVDRGDNTYGGKWVINPSGGLISKGHPLGATGLAQ 364

Query: 345 TVESVLQIRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTILR 386
             E   Q+RGEA    QVP A++ L  N+ G G  + VT+ R
Sbjct: 365 CAELCWQLRGEAGKR-QVPGAKVALQHNL-GLGGAVVVTLYR 404


>gi|11498572 3-ketoacyl-CoA thiolase (acaB-9) [Archaeoglobus fulgidus]
           >gi|7450469|pir||G69370 3-ketoacyl-CoA thiolase (acaB-9)
           homolog - Archaeoglobus fulgidus
           >gi|2649647|gb|AAB90276.1| (AE001038) 3-ketoacyl-CoA
           thiolase (acaB-9) [Archaeoglobus fulgidus]
           Length = 400
           
 Score =  163 bits (408), Expect = 3e-39
 Identities = 128/384 (33%), Positives = 188/384 (48%), Gaps = 10/384 (2%)

Query: 6   IVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAG--IDKVDSLYVGNMASGSFVEQENLGA 63
           IVG GMT        + R+L+  A+ +A+++AG  ID ++ + +G+ A  +F      G 
Sbjct: 19  IVGAGMTTFKRRLNETGRELSYLAVKQALEEAGLTIDDIEMVVMGS-APDAFDGFHMKGE 77

Query: 64  LIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDATR 123
            + D +G  N P ++V     +G  A   G   V SGL DV LVV  EKM+   P   + 
Sbjct: 78  YLLDGSGGSNRPYMRVFVGGGTGVFAPIAGYWHVASGLADVCLVVCEEKMSSVHPHPQSA 137

Query: 124 YLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYAMFK 183
           +  Y  D   +     + + + AL MR YM+ +    ED+AL +V   AN   +P A   
Sbjct: 138 F-KYIWDPILDRPLNPNLIWIFALEMRRYMHVHNIKHEDIALVSVKNKANALDHPCAQVA 196

Query: 184 RPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMGRA 243
             ITVE V+ S  +A P++  D SP  DGAAA+I+  P  A++L    D  V + G+G A
Sbjct: 197 EKITVEDVLNSEPMALPVRRLDVSPPSDGAAALIMVAPHIARQL---TDNPVWVTGVGWA 253

Query: 244 IDTINLANREDLLTLKAAKIAAEKAYKMAKVEP--KDIDFFEVHDAFTVMAALSLEALGV 301
           +DT    NR DL   +    AA+ AY+MA +    K+ID  E +D F       +E LG+
Sbjct: 254 LDTTWWTNR-DLYFPRYVAEAAKMAYRMAHITDPRKEIDVAEPYDPFDYKELHHMEGLGL 312

Query: 302 AEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGIQ 361
           A+KGE   L +EG    DGD P    GGL   G+P+ AT   +  E   Q+   A     
Sbjct: 313 AKKGEAPILTREGVTQRDGDLPTCPSGGLLGVGNPIAATMGVKACEIYWQLAYRAGKRQV 372

Query: 362 VPDAEIGLTQNIGGTGSNITVTIL 385
             +   G+ Q  G      TV ++
Sbjct: 373 AKEVTTGVCQAWGDLMQVGTVMVM 396


>sp|P22307|NLTP_HUMAN NONSPECIFIC LIPID-TRANSFER PROTEIN PRECURSOR (NSL-TP) (STEROL
           CARRIER PROTEIN 2) (SCP-2) (STEROL CARRIER PROTEIN X)
           (SCP-X) (SCPX) >gi|2136204|pir||I38205 sterol carrier
           protein-X/sterol carrier protein-2 - human
           >gi|432975|gb|AAA03557.1| (M75883) sterol carrier
           protein-X/sterol carrier protein-2 [Homo sapiens]
           Length = 547
           
 Score =  162 bits (406), Expect = 6e-39
 Identities = 125/402 (31%), Positives = 189/402 (46%), Gaps = 24/402 (5%)

Query: 1   MEKPIIVGVGMT----PVGEHWRTSLRDLAVEAILKAMDDAGI--DKVDSLYVGNMASGS 54
           + +  +VGVGMT    P  E+ R    DLA EA  KA+ DA I    VD   VG +   S
Sbjct: 11  LRRVFVVGVGMTKFVKPGAENSR-DYPDLAEEAGKKALADAQIPYSAVDQACVGYVFGDS 69

Query: 55  FVEQENLGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMT 114
              Q      I    G+  IP + V   CA+G  A+    + +  G+ + VL +G EKM+
Sbjct: 70  TCGQR----AIYHSLGMTGIPIINVNNNCATGSTALFMARQLIQGGVAECVLALGFEKMS 125

Query: 115 DAWPSDATRYLAYASDAEWELF---HGVSFVALNALIM----RHYMNTYGYTEEDLALFA 167
                         +D   +L    +G+S   +   +     + +M  YG   E  A   
Sbjct: 126 KGSLGIKFSDRTIPTDKHVDLLINKYGLSAHPVAPQMFGYAGKEHMEKYGTKIEHFAKIG 185

Query: 168 VNAHANGAKNPYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKEL 227
              H +   NPY+ F+   +++ VM S  + D L +    P  DGAAA I+      ++ 
Sbjct: 186 WKNHKHSVNNPYSQFQDEYSLDEVMASKEVFDFLTILQCCPTSDGAAAAILASEAFVQKY 245

Query: 228 GIPKDKWVEIAGMGRAIDTINLANREDLLTLKA---AKIAAEKAYKMAKVEPKDIDFFEV 284
           G+ + K VEI       D  +    + ++ +     +K AA K Y+ + + P DID  E+
Sbjct: 246 GL-QSKAVEILAQEMMTDLPSSFEEKSIIKMVGFDMSKEAARKCYEKSGLTPNDIDVIEL 304

Query: 285 HDAFTVMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQ 344
           HD F+    L+ EALG+  +G+GA L   G     G + I   GGL ++GHP+GATG+ Q
Sbjct: 305 HDCFSTNELLTYEALGLCPEGQGATLVDRGDNTYGGKWVINPSGGLISKGHPLGATGLAQ 364

Query: 345 TVESVLQIRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTILR 386
             E   Q+RGEA    QVP A++ L  N+ G G  + VT+ +
Sbjct: 365 CAELCWQLRGEAGKR-QVPGAKVALQHNL-GIGGAVVVTLYK 404


>gb|AAB41286.1| (U11313) sterol carrier protein-X/sterol carrier protein-2 [Homo
           sapiens]
           Length = 547
           
 Score =  159 bits (399), Expect = 4e-38
 Identities = 124/402 (30%), Positives = 188/402 (45%), Gaps = 24/402 (5%)

Query: 1   MEKPIIVGVGMT----PVGEHWRTSLRDLAVEAILKAMDDAGI--DKVDSLYVGNMASGS 54
           + +  +VGVGMT    P  E+ R    DLA EA  KA+ DA I    VD   VG +   S
Sbjct: 11  LRRVFVVGVGMTKFVKPGAENSR-DYPDLAEEAGKKALADAQIPYSAVDQACVGYVFGDS 69

Query: 55  FVEQENLGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMT 114
              Q      I    G+  IP + V   CA+G  A+    + +  G+ + VL +G EKM+
Sbjct: 70  TCGQR----AIYHSLGMTGIPIINVNNNCATGSTALFMARQLIQGGVAECVLALGFEKMS 125

Query: 115 DAWPSDATRYLAYASDAEWELF---HGVSFVALNALIM----RHYMNTYGYTEEDLALFA 167
                         +D   +L    +G+S   +   +     + +M  YG   E  A   
Sbjct: 126 KGSLGIKFSDRTIPTDKHVDLLINKYGLSAHPVAPQMFGYAGKEHMEKYGTKIEHFAKIG 185

Query: 168 VNAHANGAKNPYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKEL 227
              H +   NPY+ F+   +++ VM S  + D L +    P  DGAAA I+      ++ 
Sbjct: 186 WKNHKHSVNNPYSQFQDEYSLDEVMASKEVFDFLTILQCCPTSDGAAAAILASEAFVQKY 245

Query: 228 GIPKDKWVEIAGMGRAIDTINLANREDLLTLKA---AKIAAEKAYKMAKVEPKDIDFFEV 284
           G+ + K VEI       D  +    + ++ +     +K AA K Y+ + + P DID  E+
Sbjct: 246 GL-QSKAVEILAQEMMTDLPSSFEEKSIIKMVGFDMSKEAARKCYEKSGLTPNDIDVIEL 304

Query: 285 HDAFTVMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQ 344
           HD F+    L+ EALG+  +G+GA L   G     G + I   GGL ++GHP+GATG+ Q
Sbjct: 305 HDCFSTNELLTYEALGLCPEGQGATLVDRGDNTYGGKWVINPSGGLISKGHPLGATGLAQ 364

Query: 345 TVESVLQIRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTILR 386
             E   Q+RGEA    QVP A++ L  N+   G  + VT+ +
Sbjct: 365 CAELCWQLRGEAGKR-QVPGAKVALQHNL-DIGGAVVVTLYK 404


>gb|AAC15422.1| (AF051897) sterol carrier protein X [Oryctolagus cuniculus]
           Length = 547
           
 Score =  159 bits (397), Expect = 7e-38
 Identities = 119/397 (29%), Positives = 187/397 (46%), Gaps = 25/397 (6%)

Query: 1   MEKPIIVGVGMTPVGEHWRTSLRD---LAVEAILKAMDDAGI--DKVDSLYVGNMASGSF 55
           + +  +VGVGMT   +      RD   +A EA  KA+ DA I    V+   +G +   S 
Sbjct: 11  LPRVFVVGVGMTKFVKPGTEDARDYPDMAKEAGQKALADAQIPYSAVEQACIGYVYGDST 70

Query: 56  VEQENLGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTD 115
             Q      +    GL  IP + V   C++G  A+  G + +  G+ + VL +G EKM  
Sbjct: 71  CGQR----AVYHSLGLTGIPIINVNNNCSTGSTALFMGRQLIQGGMAECVLALGFEKMER 126

Query: 116 AWPSDATRYLAYASDAEWELFHGVSFVALNALIM---------RHYMNTYGYTEEDLALF 166
              S   ++    +  +  L   ++   L+A  +         + +M  YG   E  A  
Sbjct: 127 G--SLGAKFPDRTNPMDKHLDVLINKYGLSAHPVAPQMFGSAGKEHMEKYGTKIEHFAKI 184

Query: 167 AVNAHANGAKNPYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKE 226
               H +   NPY+ F++  +++ VM S  I D L +    P  DGAAA I+   E  K+
Sbjct: 185 GWKNHKHSVNNPYSQFQKEYSLDEVMSSRPIFDFLTVLQCCPTSDGAAAAILASEEFVKK 244

Query: 227 LGIPKDKWVEIAGMGRAIDTINLANREDLLTLKA---AKIAAEKAYKMAKVEPKDIDFFE 283
            G+ + K VEI       D  +    + ++ +     +K AA + Y+ + + P DID  E
Sbjct: 245 YGL-QSKAVEILAQEMVTDFPSSFEEKSIIKMVGFDMSKEAARRCYEKSGLRPSDIDVIE 303

Query: 284 VHDAFTVMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVY 343
           +HD F+    L+ EALG+  +G+G  L   G     G + I   GGL ++GHP+GATG+ 
Sbjct: 304 LHDCFSANELLTYEALGLCPEGKGGALVDRGDNTYGGKWVINPSGGLISKGHPLGATGLA 363

Query: 344 QTVESVLQIRGEAPNGIQVPDAEIGLTQNIGGTGSNI 380
           Q  E   Q+RGEA    QVP A++ L  N+G  G+ +
Sbjct: 364 QCAELCWQLRGEAGKR-QVPGAKVALQHNLGLGGAAV 399


>pir||A34635 nonspecific lipid transfer protein precursor - rat  (fragment)
           >gi|205770|gb|AAA41726.1| (M58287) non-specific lipid
           transfer protein [Rattus sp.]
           Length = 515
           
 Score =  159 bits (397), Expect = 7e-38
 Identities = 118/377 (31%), Positives = 179/377 (47%), Gaps = 23/377 (6%)

Query: 24  DLAVEAILKAMDDAGI--DKVDSLYVGNMASGSFVEQENLGALIADWAGLGNIPAVKVEA 81
           DLA EA  KA+ D  I    V+   VG +   S   Q      I    GL  IP + V  
Sbjct: 5   DLAKEAGQKALADRQIPYSAVEQACVGYVYGESTCGQR----AIYHSLGLTGIPIINVNN 60

Query: 82  ACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDATRYLAYASDAEWELFHGVSF 141
            C++G  A+    + V  GL + VL +G EKM     S  T+Y   ++  E  +   ++ 
Sbjct: 61  NCSTGSTALFMAQQLVQGGLANCVLALGFEKMEKG--SLGTKYSDRSNPLEKHIDVLINK 118

Query: 142 VALNALIM---------RHYMNTYGYTEEDLALFAVNAHANGAKNPYAMFKRPITVETVM 192
             ++A            + +M TYG   E  A      H +   NPY+ F+   +++ +M
Sbjct: 119 YGMSACPFAPQLFGSAGKEHMETYGTKVEHFAKIGWKNHKHSVNNPYSQFQDEYSLDEIM 178

Query: 193 KSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMGRAIDTINLANR 252
           KS  + D L +    P  DGAAA I++  E  ++ G+ + K VEI       D  +    
Sbjct: 179 KSRPVFDFLTVLQCCPTSDGAAAAIVSSEEFVQKHGL-QSKAVEIVAQEMVTDMPSTFEE 237

Query: 253 EDLLTLKA---AKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALGVAEKGEGAK 309
           + ++ +     +K AA K Y+ + + P D+D  E+HD F+    L+ EALG+  +G+G  
Sbjct: 238 KSVIKMVGYDMSKEAARKCYEKSGLGPSDVDVIELHDCFSTNELLTYEALGLCPEGQGGA 297

Query: 310 LAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGIQVPDAEIGL 369
           L   G     G + I   GGL ++GHP+GATG+ Q  E   Q+RGEA    QVP A++ L
Sbjct: 298 LVDRGDNTYGGKWVINPSGGLISKGHPLGATGLAQCAELCWQLRGEAGKR-QVPGAKVAL 356

Query: 370 TQNIGGTGSNITVTILR 386
             N+ G G    VT+ R
Sbjct: 357 QHNL-GLGGAAVVTLYR 372


>gb|AAF53713.1| (AE003660) ScpX gene product [Drosophila melanogaster]
           Length = 544
           
 Score =  157 bits (394), Expect = 2e-37
 Identities = 116/397 (29%), Positives = 181/397 (45%), Gaps = 24/397 (6%)

Query: 6   IVGVGMTPVGEHWRTS---LRDLAVEAILKAMDDAGIDKVDSLYVGNMASGSFVEQENLG 62
           +VGVGMT   +  R +     D A EAI KA+ DAGI   +   V    +G        G
Sbjct: 8   VVGVGMTKFEKPGRQADVCYPDFAREAITKALQDAGIKYEE---VQQAVAGYVYGDSTCG 64

Query: 63  ALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDAT 122
                  G+  IP   V   C++G +A+    + V SG  D VL +G EKM     S ++
Sbjct: 65  QRAIYEVGMTGIPVYNVNNNCSTGSSALYLAKQIVESGNADCVLALGFEKMERG--SLSS 122

Query: 123 RYLAYASDAEWELFHGVSFVALNALIM---------RHYMNTYGYTEEDLALFAVNAHAN 173
           +Y   A+  E  +        + A  M         + +M  YG   E     A   H +
Sbjct: 123 KYFDRANPMERHITEMGELAEIGAGPMAAQIFGNAGKEHMKKYGTKPEHFGKIAWKNHKH 182

Query: 174 GAKNPYAMFKRPITVETVMKSPYIADP-LKLFDASPVCDGAAAVIITIPEKAKELGIPKD 232
              NPY+ F+   T+E +MKSP + +  L      P  DG+ A I+      +  G+ K 
Sbjct: 183 SVNNPYSQFRDEYTLEQIMKSPQVVEGVLTKLQCCPTSDGSGAAILASEAFVRRHGLEKQ 242

Query: 233 KWVEIAGMGRAIDTINLANREDLLTLKAA---KIAAEKAYKMAKVEPKDIDFFEVHDAFT 289
             VEI GM  A D  +    + L+ +      ++A ++ +  +  +P+D+   E+HD F+
Sbjct: 243 A-VEIVGMEMASDPASTFADKSLMKIAGTDMTRLATQRLFAKSGYKPQDVQVVELHDCFS 301

Query: 290 VMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESV 349
               ++ EALG+  +G   +    G     G + +   GGL ++GHP+GATG+ Q  E  
Sbjct: 302 ANELITYEALGLCGEGNAGEFIDAGDNTYGGKFVVNPSGGLISKGHPLGATGLAQCAELC 361

Query: 350 LQIRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTILR 386
            Q+RG A    QVP+A++ L  N+ G G  + V + R
Sbjct: 362 WQLRGLAEKR-QVPNAQLALQHNL-GLGGAVVVALYR 396


>sp|Q07598|NLTP_CHICK NONSPECIFIC LIPID-TRANSFER PROTEIN PRECURSOR (NSL-TP) (STEROL
           CARRIER PROTEIN 2) (SCP-2) (STEROL CARRIER PROTEIN X)
           (SCP-X) (SCPX) >gi|479569|pir||S34744 sterol carrier
           protein - chicken >gi|304423|gb|AAA02488.1| (L09231)
           sterol carrier protein-2 [Gallus gallus]
           Length = 547
           
 Score =  156 bits (391), Expect = 3e-37
 Identities = 121/393 (30%), Positives = 184/393 (46%), Gaps = 21/393 (5%)

Query: 6   IVGVGMTPVGEHWRTSLR--DLAVEAILKAMDDAGI--DKVDSLYVGNMASGSFVEQENL 61
           +VGVGMT   +    S+   DLA EA  KA+ DAGI    V+   VG +   S   Q   
Sbjct: 20  VVGVGMTKFAKPSENSVDYPDLAKEAGQKALADAGIPYSAVEQACVGYVYGDSTCGQR-- 77

Query: 62  GALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDA 121
              I    GL  IP + V   CA+G  A+    + V  GL D VL +G E+M     +  
Sbjct: 78  --AIYHGLGLTGIPIINVNNNCATGSTALFMSRQLVEGGLADCVLALGFERMAKGSLASG 135

Query: 122 TRYLAYASDAEWELF---HGVSFVALNALIM----RHYMNTYGYTEEDLALFAVNAHANG 174
                   D   E+    +G++   +   +     + +M  YG   E  A  A   H++ 
Sbjct: 136 FSDRTNPMDKHLEIMINKYGLASAPITPQMFANAGKEHMEKYGTNPEYFAKIAWKNHSHS 195

Query: 175 AKNPYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKW 234
             NPY+ F++  T++ V++S  + D L +    P  +GAAA I+   +  K   + + + 
Sbjct: 196 TNNPYSQFQKKYTLDEVLQSRKVFDFLTVLQCCPTSNGAAAAILASEDFVKRHKL-QPQA 254

Query: 235 VEIAGMGRAIDTINLANREDLLTLKA---AKIAAEKAYKMAKVEPKDIDFFEVHDAFTVM 291
           VEI     A D  +       + +      K AAEK +K A ++P D+D  E+HD F+V 
Sbjct: 255 VEILAQVMATDYPSTFEENSCMKMVGYDMTKKAAEKCFKKAGLKPTDVDVIELHDCFSVN 314

Query: 292 AALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQ 351
             ++ EALG+  +G+   L   G     G + I   GGL ++GHP+GATG+ Q+ E   Q
Sbjct: 315 EFITYEALGLCPEGKACDLIDRGDNTYGGKWVINPSGGLISKGHPLGATGLAQSAELCWQ 374

Query: 352 IRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTI 384
           +RG A    +V  A   L  N+ G G  + VT+
Sbjct: 375 LRGLAGRR-EVGGARRALQHNL-GLGGAVVVTL 405


>pir||B40407 sterol carrier protein 2-related form, 58.85K - human
           Length = 546
           
 Score =  153 bits (383), Expect = 3e-36
 Identities = 121/402 (30%), Positives = 187/402 (46%), Gaps = 24/402 (5%)

Query: 1   MEKPIIVGVGMT----PVGEHWRTSLRDLAVEAILKAMDDAGI--DKVDSLYVGNMASGS 54
           + +  +VGVGMT    P  E+ R    DLA EA  KA+ DA I    VD   VG +   S
Sbjct: 10  LRRVFVVGVGMTKFEKPGAENSR-DYPDLAEEAGKKALADAQIPYSAVDQACVGYVFGDS 68

Query: 55  FVEQENLGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMT 114
              Q      I    G+  IP + V   CA+G  A+    + +  G+ + VL +G EKM+
Sbjct: 69  TCGQR----AIYHSLGMTGIPIINVNNNCATGSTALFMARQLIQGGVAECVLALGFEKMS 124

Query: 115 DAWPSDATRYLAYASDAEWELF---HGVSFVALNALIM----RHYMNTYGYTEEDLALFA 167
                         +D   +L    +G+S   +   +     + +M  YG   E  A   
Sbjct: 125 KGSLGIKFSDRTIPTDKHVDLLINKYGLSAHPVAPQMFGYAGKEHMEKYGTKIEHFAKIG 184

Query: 168 VNAHANGAKNPYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKEL 227
              H +   NPY+ F+   +++ VM S  + D L +    P  DGAAA I+      ++ 
Sbjct: 185 WKNHKHSVNNPYSQFQDEYSLDEVMASKEVFDFLTILQCCPTSDGAAAAILASEHLVQKY 244

Query: 228 GIPKDKWVEIAGMGRAIDTINLANREDLLTLKA---AKIAAEKAYKMAKVEPKDIDFFEV 284
           G+ + K VEI       D  +    + ++ +     +K AA K Y+ + +   DI   E+
Sbjct: 245 GL-QSKAVEILAQEMMTDLPSSFEEKSIIKMVGFDMSKEAARKCYETSGLGHNDIGLIEL 303

Query: 285 HDAFTVMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQ 344
           HD  +    L+ EALG+  +G+GA L   G     G++ I   GGL ++GHP+GATG+ +
Sbjct: 304 HDCCSTNELLTYEALGLCPEGQGATLVDRGDNTYGGNWVINPSGGLISKGHPLGATGLAE 363

Query: 345 TVESVLQIRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTILR 386
             E   Q+RGEA    QVP A++ L  N+ G G  + VT+ +
Sbjct: 364 CAELCWQLRGEAGKR-QVPGAKVALQHNL-GIGGAVVVTLYK 403


>gb|AAF53712.1| (AE003660) CG17597 gene product [Drosophila melanogaster]
           Length = 378
           
 Score =  152 bits (379), Expect = 9e-36
 Identities = 113/394 (28%), Positives = 179/394 (44%), Gaps = 47/394 (11%)

Query: 6   IVGVGMTPVGEHWRTS---LRDLAVEAILKAMDDAGI--DKVDSLYVGNMASGSFVEQEN 60
           ++GVGMT   +  R +     D A EAI KA+ DAGI  ++V     G +   S   Q  
Sbjct: 8   VIGVGMTKFEKPGRRADACYPDFAKEAITKALQDAGIKFEEVQQAVAGYVYGDSTCGQRA 67

Query: 61  LGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSD 120
           +  +     G+  IP   V   C++G +A+    + V SG  + VL +G EKM       
Sbjct: 68  IYEV-----GMTGIPVYNVNNNCSTGSSALYLAKQIVESGNSECVLALGFEKMERG---- 118

Query: 121 ATRYLAYASDAEWELFHGVSFVALNALIM----RHYMNTYGYTEEDLALFAVNAHANGAK 176
                                 +L+A I     + +M  YG   E     A   H +   
Sbjct: 119 ----------------------SLSAKIFGNAGKEHMKKYGTKPEHFGKIAWKNHKHSVN 156

Query: 177 NPYAMFKRPITVETVMKSPYIADP-LKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWV 235
           NPY+ F+   T+E +MKSP + +  L      P  DG+ A I+      +  G+ K   V
Sbjct: 157 NPYSQFRDEYTLEQIMKSPQVVEGVLTKLQCCPTSDGSGAAILASEAFVRRHGLEKQA-V 215

Query: 236 EIAGMGRAIDTINLANREDLLTLKAA---KIAAEKAYKMAKVEPKDIDFFEVHDAFTVMA 292
           EI GM  A D  +    + L+ +      ++A E+ +  +  +P+D+   E+HD F+   
Sbjct: 216 EIVGMEMASDPASTFADKSLMKIAGTDMTRLATERLFAKSGYKPQDVQVVELHDCFSANE 275

Query: 293 ALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQI 352
            ++ EALG+  +G+  +    G     G + +   GGL ++GHP+GATG+ Q  E   Q+
Sbjct: 276 LITYEALGLCGEGKAGEFIDAGDNTYGGKFVVNPSGGLISKGHPLGATGLAQCAELCWQL 335

Query: 353 RGEAPNGIQVPDAEIGLTQNIGGTGSNITVTILR 386
           RG A    QVP+A++ L  N+ G G  + V + R
Sbjct: 336 RGLAEKR-QVPNAQLALQHNL-GLGGAVVVALYR 367


>gb|AAK40853.1| Acetyl-CoA c-acetyltransferase (acetoacetyl-CoA thiolase) (acaB-1)
           [Sulfolobus solfataricus]
           Length = 359
           
 Score =  150 bits (376), Expect = 2e-35
 Identities = 100/345 (28%), Positives = 172/345 (48%), Gaps = 28/345 (8%)

Query: 11  MTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVDSLYVGNMASGSFVEQENLGALIADWAG 70
           M P+  ++   + DL +EA      +  ++ +D + V N  S        +   IA+  G
Sbjct: 11  MIPIDRYYEYDIYDLVIEAYKNFEGEYDVNSIDLIVVANAYSQKLNNASLIAPKIAEKIG 70

Query: 71  LGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDATRYLAYASD 130
             N+P++KV+ A ASGGAA+      + S + + VL+VGVEK +D +PS         + 
Sbjct: 71  KPNVPSIKVDNADASGGAALLTAYSLIKSNMVNSVLIVGVEKQSD-YPSKYLYDAISTNL 129

Query: 131 AEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYAMFKRPITVET 190
            ++  ++G+S  ++ AL+MR YM  YG      A +A+  H N  +NP+A  +  + + T
Sbjct: 130 DDYMFYNGISSHSVAALLMRQYMKRYGVDRNYFANWAIKMHKNATENPFAYLRFQVDLNT 189

Query: 191 VMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMGRAIDTINLA 250
           V+ S  I+DP++LFD     DGAA ++++  +    + I K               ++  
Sbjct: 190 VINSQIISDPVRLFDVGARADGAAILLLSNNKTESAVKINK--------------ILSAQ 235

Query: 251 NREDLL-TLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALGVAEKGEGAK 309
            R D   +L + ++  +K  ++   E   ID   +HD++++MAAL LE  G+ E G+   
Sbjct: 236 ARYDFSPSLPSVRMLRDK-LELKFSERTGID---IHDSYSIMAALMLEEAGIFESGKSLH 291

Query: 310 LAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRG 354
                 + +         GGLKARGH  GA+ +YQ  E+ +Q+ G
Sbjct: 292 NLDSVNVNLG--------GGLKARGHVGGASAIYQLAEAHMQLIG 328


>emb|CAB57766.1| (Y18930) acetyl CoA synthase [Sulfolobus solfataricus]
           Length = 359
           
 Score =  150 bits (376), Expect = 2e-35
 Identities = 100/345 (28%), Positives = 172/345 (48%), Gaps = 28/345 (8%)

Query: 11  MTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVDSLYVGNMASGSFVEQENLGALIADWAG 70
           M P+  ++   + DL +EA      +  ++ +D + V N  S        +   IA+  G
Sbjct: 11  MIPIDRYYEYDIYDLVIEAYKNFEGEYDVNSIDLIVVANAYSQKLNNASLIAPKIAEKIG 70

Query: 71  LGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDATRYLAYASD 130
             N+P++KV+ A ASGGAA+      + S + + VL+VGVEK +D +PS         + 
Sbjct: 71  KPNVPSIKVDNADASGGAALLTAYSLIKSNMVNSVLIVGVEKQSD-YPSKYLYDAISTNL 129

Query: 131 AEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYAMFKRPITVET 190
            ++  ++G+S  ++ AL+MR YM  YG      A +A+  H N  +NP+A  +  + + T
Sbjct: 130 DDYMFYNGISSHSVAALLMRQYMKRYGVDRNYFANWAIKMHKNATENPFAYLRFQVDLNT 189

Query: 191 VMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMGRAIDTINLA 250
           V+ S  I+DP++LFD     DGAA ++++  +    + I K               ++  
Sbjct: 190 VINSQIISDPVRLFDVGARADGAAILLLSNNKTESAVKINK--------------ILSAQ 235

Query: 251 NREDLL-TLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALGVAEKGEGAK 309
            R D   +L + ++  +K  ++   E   ID   +HD++++MAAL LE  G+ E G+   
Sbjct: 236 ARYDFSPSLPSVRMLRDK-LELKFSERTGID---IHDSYSIMAALMLEEAGIFESGKSLH 291

Query: 310 LAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRG 354
                 + +         GGLKARGH  GA+ +YQ  E+ +Q+ G
Sbjct: 292 NLDSVNVNLG--------GGLKARGHVGGASAIYQLAEAHMQLIG 328


>pir||G72467 probable non specific lipid-transfer protein APE2384 - Aeropyrum
           pernix (strain K1) >gi|5106088|dbj|BAA81399.1|
           (AP000064) 394aa long hypothetical non specific
           lipid-transfer protein [Aeropyrum pernix]
           Length = 394
           
 Score =  148 bits (369), Expect = 1e-34
 Identities = 120/358 (33%), Positives = 173/358 (47%), Gaps = 10/358 (2%)

Query: 3   KPIIVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGID--KVDSLYVGNMASGSFVEQEN 60
           K  +VG G+T        + R+LA EA  +A+D AG+    +D + +G+ A  +F     
Sbjct: 12  KVAVVGAGITLFRRRMLETPRELAWEAARQALDSAGLTLRDIDCVVIGS-APDAFDGVHM 70

Query: 61  LGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSD 120
            G  +AD +G    P V+V     +G          V SGL   VL V  EKM+ A P  
Sbjct: 71  KGEYLADGSGGLFKPTVRVYVGGGTGVFVPIAAWWHVASGLCRTVLAVAEEKMSHARPHP 130

Query: 121 ATRYLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYA 180
              + AY  D   E   G + + + AL MR YM+    ++E +AL +V    N   +P A
Sbjct: 131 QGVF-AYIWDPVLERPLGPNLLWIFALEMRRYMHKCNVSKETIALVSVKNKRNALDHPAA 189

Query: 181 MFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGM 240
                ITVE V+ S  +  P+   D SPV DGAAA+++    +A+ +    D  V I G+
Sbjct: 190 QAAANITVEDVLNSEVLVWPVNRLDVSPVSDGAAALVLASENEARRV---TDSPVWIEGV 246

Query: 241 GRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEP--KDIDFFEVHDAFTVMAALSLEA 298
           G  +D  +  NRE L   +  + AA  AYKMA +E   +DIDF E +D F       +E 
Sbjct: 247 GWTLDNTHWYNRE-LGYPRYVQYAARMAYKMAGIERPWRDIDFAEPYDPFDYKELHHIEG 305

Query: 299 LGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEA 356
           L +A   E  KL +EG     G+ P    GGL   G+P+ A G+ +  E   Q+R EA
Sbjct: 306 LMLARPCEAPKLLEEGWFDRSGELPTSPSGGLLGVGNPIAAAGLMKAAELFWQLRYEA 363


>gi|11497751 3-ketoacyl-CoA thiolase (acaB-4) [Archaeoglobus fulgidus]
           >gi|7450482|pir||F69266 3-ketoacyl-CoA thiolase (acaB-4)
           homolog - Archaeoglobus fulgidus
           >gi|2650511|gb|AAB91095.1| (AE001097) 3-ketoacyl-CoA
           thiolase (acaB-4) [Archaeoglobus fulgidus]
           Length = 398
           
 Score =  145 bits (361), Expect = 1e-33
 Identities = 125/375 (33%), Positives = 187/375 (49%), Gaps = 32/375 (8%)

Query: 6   IVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVDSLYVGNMASGS--FVEQENLGA 63
           I+G  ++ +      +  +   E   +AM  AG+++ D   VG + S S  F++    G 
Sbjct: 24  IIGYAVSKLEWDAEKTREEAVFEVTREAMRRAGVERED---VGTVISASTDFLD----GR 76

Query: 64  LIADWAGLGNIPA-VKVEAACASGGA-AVQEGAKAVLSGLEDVVLVVGVEKMTDAW---P 118
            I++   +G   A +K E+     G  A    A+ ++SG+ DV L +     T +W   P
Sbjct: 77  TISNCMLIGASGAYLKDESKAEEDGMYAALYAAQRIMSGVHDVALAIS---HTHSWIFNP 133

Query: 119 SDATRYLAYA-SDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKN 177
              ++Y+     D + EL +G++  AL A   R YM+  G  E  LA   V    N AK 
Sbjct: 134 HQVSQYMLEPWFDRQNELLNGITLAALQA---RLYMSRSGVDEGHLAEVCVKNLRNAAKV 190

Query: 178 PYAMFKRP-ITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVE 236
           PYA  K   +TVE V++S   + PL     +P CDGAAAV++   E AKEL    D+ V 
Sbjct: 191 PYAFRKMADVTVEEVLESKLYSSPLTELMIAPPCDGAAAVVLASEEVAKEL---CDEPVW 247

Query: 237 IAGMGRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEP--KDIDFFEVHDAFTVMAAL 294
           I G+G + D        DL  L++ ++AAEKAY+MA +E   + ID  E+ + F     +
Sbjct: 248 IKGIGNSCD--RYLRDRDLGRLESLRLAAEKAYRMAGIEEPFRQIDVAEISERFAHHELM 305

Query: 295 SLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRG 354
           + EALG    G G  L +EG   + GD P+   GG  A G  + ATG+ + +E+  Q+RG
Sbjct: 306 AYEALGFCRDGMGKVLIEEGITEVYGDMPVNPSGGALA-GDAICATGMIRLIEAARQVRG 364

Query: 355 EAPNGIQVPDAEIGL 369
           EA N  QV D    L
Sbjct: 365 EAEN--QVEDCRTAL 377


>pir||T27202 hypothetical protein Y57A10C.6 - Caenorhabditis elegans
           >gi|2190267|dbj|BAA20377.1| (D86473) 3-keto-acyl-CoA
           thiolase [Caenorhabditis elegans]
           >gi|3881142|emb|CAA19548.1| (AL023847) contains
           similarity to Pfam domain: PF00108 (Thiolase),
           Score=230.7, E-value=6.8e-66, N=1~cDNA EST EMBL:Z14647
           comes from this gene~cDNA EST yk168e11.3 comes from this
           gene~cDNA EST yk168e11.5 comes from this gene~cDNA EST
           yk146e10.5 comes f>
           Length = 412
           
 Score =  144 bits (360), Expect = 1e-33
 Identities = 111/396 (28%), Positives = 177/396 (44%), Gaps = 24/396 (6%)

Query: 3   KPIIVGVGMTPV---GEHWRTSLRDLAVEAILKAMDDAGI--DKVDSLYVGNMASGSFVE 57
           K  IVGVGMT     G        D+  EA+  A+DD  +    +    VG +  G+   
Sbjct: 7   KVYIVGVGMTKFCKPGSVPGWDYPDMVKEAVTTALDDCKMKYSDIQQATVGYLFGGTCCG 66

Query: 58  QENLGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTD-- 115
           Q  L  +     GL  IP   V  ACASG + +  G + + SG  DVVL  G E+M    
Sbjct: 67  QRALYEV-----GLTGIPIFNVNNACASGSSGLFLGKQIIESGNSDVVLCAGFERMAPGS 121

Query: 116 ----AWPSDATRYLAYASDAEWELFHGVSFVALNALIM----RHYMNTYGYTEEDLALFA 167
               A P D          +     +G+    + A +     + +M  YG   E  A  A
Sbjct: 122 LENLAAPIDDRALSVDKHISVMSETYGLEPAPMTAQMFGNAAKEHMEKYGSKREHYAKIA 181

Query: 168 VNAHANGAKNPYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKEL 227
              H +   NP + F +  +++ V+ +  I D + L + SP  DGAAA ++   +  ++ 
Sbjct: 182 YKNHLHSVHNPKSQFTKEFSLDQVINARKIYDFMGLLECSPTSDGAAAAVLVSEKFLEKN 241

Query: 228 GIPKDKWVEIAGMGRAIDTINLANRED---LLTLKAAKIAAEKAYKMAKVEPKDIDFFEV 284
              K + VEI G+    D  ++        ++     +  A++ +   K+ P D+   E+
Sbjct: 242 PRLKAQAVEIVGLKLGTDEPSVFAENSNIKMIGFDMIQKLAKQLWAETKLTPNDVQVIEL 301

Query: 285 HDAFTVMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQ 344
           HD F     ++ EA+G+   G+G  +         G + I   GGL ++GHP+GATGV Q
Sbjct: 302 HDCFAPNELITYEAIGLCPVGQGHHIVDRNDNTYGGKWVINPSGGLISKGHPIGATGVAQ 361

Query: 345 TVESVLQIRGEAPNGIQVPDAEIGLTQNIGGTGSNI 380
            VE   Q+RG+     QVP+ ++ +  NIG  G+ +
Sbjct: 362 AVELSNQLRGKCGKR-QVPNCKVAMQHNIGIGGAGV 396


>emb|CAA66277.1| (X97685) sterol carrier protein x [Drosophila melanogaster]
           Length = 543
           
 Score =  141 bits (352), Expect = 1e-32
 Identities = 113/397 (28%), Positives = 176/397 (43%), Gaps = 24/397 (6%)

Query: 6   IVGVGMTPVGEHWRTS---LRDLAVEAILKAMDDAGIDKVDSLYVGNMASGSFVEQENLG 62
           +VGVGMT   +  R +     D A EAI KA+ DAGI   +   V    +G        G
Sbjct: 8   VVGVGMTKFEKPGRRADVCYPDFAREAITKALQDAGIKYEE---VQQAVAGYVYGDSTCG 64

Query: 63  ALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDAT 122
                  G+  IP   V   C++G +A+    + V SG  D VL +G EKM     S ++
Sbjct: 65  QRAIYEVGMTGIPVYNVNNNCSTGSSALYLAKQIVESGNADCVLALGFEKMERG--SLSS 122

Query: 123 RYLAYASDAEWELFHGVSFVALNALIM---------RHYMNTYGYTEEDLALFAVNAHAN 173
           +Y   A+  E  +        + A  M         + +M  YG   E     A   H +
Sbjct: 123 KYFDRANPMERHITEMGELAEIGAGPMAAQIFGNAGKEHMKKYGTKPEHFGKIAWKNHKH 182

Query: 174 GAKNPYAMFKRPITVETVMKSPYIADP-LKLFDASPVCDGAAAVIITIPEKAKELGIPKD 232
              NPY+ F+   T+E +MKSP + +  L      P  DG+ A I+      +  G+ K 
Sbjct: 183 TVNNPYSQFRDEYTLEQIMKSPQVVEGVLTKLQCCPTSDGSGAAILASEAFVRRNGLEKQ 242

Query: 233 KWVEIAGMGRAIDTINLANREDLLTLKAA---KIAAEKAYKMAKVEPKDIDFFEVHDAFT 289
             VEI GM  A D  +    + L+ +      ++A E+ +  +   P+   ++    A  
Sbjct: 243 A-VEIVGMEMASDPASTFADKSLMKIAGTDMTRLATERLFAKSGTSPRMSRWWNCTIASR 301

Query: 290 VMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESV 349
               ++ EALG+  +G+  +    G     G + +   GGL ++GHP+GATG+ Q  E  
Sbjct: 302 ANDLITYEALGLCGEGKAGEFIDAGDNTYGGKFVVNPSGGLISKGHPLGATGLAQCAELC 361

Query: 350 LQIRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTILR 386
            Q+RG A    QVP+A++ L  N+ G G  + V + R
Sbjct: 362 WQLRGLAEKR-QVPNAQLALQHNL-GLGGAVVVALYR 396


>gi|11497750 3-ketoacyl-CoA thiolase (acaB-3) [Archaeoglobus fulgidus]
           >gi|7450481|pir||E69266 3-ketoacyl-CoA thiolase (acaB-3)
           homolog - Archaeoglobus fulgidus
           >gi|2650512|gb|AAB91096.1| (AE001097) 3-ketoacyl-CoA
           thiolase (acaB-3) [Archaeoglobus fulgidus]
           Length = 411
           
 Score =  140 bits (350), Expect = 2e-32
 Identities = 118/412 (28%), Positives = 179/412 (42%), Gaps = 33/412 (8%)

Query: 1   MEKPIIVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGI--DKVDSLYVGNMASGSFVEQ 58
           M +  I+G G +  G     S  +L  EA+  A++DA I  + +++  VGNM     + Q
Sbjct: 1   MRRVAIIGCGQSKHGRRTDVSQAELVAEAVWAAIEDASIAPEDIEAYAVGNMQGFGGICQ 60

Query: 59  ENLGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWP 118
            +L  + AD+   G     +V      GG+    G   V SG+ DVVL V  EK +D+  
Sbjct: 61  PDL--VFADYIAAGGKAMQRVATGGTVGGSTAHLGYYEVASGMYDVVLAVSWEKHSDSAE 118

Query: 119 SDATRYLAYASDAEWELFHGVSF--------------VALNALIMRHYMNTYGYTEEDLA 164
             AT  L + + A       +                  ++A     YM   G + E   
Sbjct: 119 PGATTGLLHVAFANLSYMMKIGMDMRSFAIMGLAGAAAGISAYQAAFYMARSGCSIEHFD 178

Query: 165 LFAVNAHANGAKNPYAMFKRP-ITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEK 223
           + A  A  N AKN YA  K P  T E + K+  +  P++     P  DGA+ VI    + 
Sbjct: 179 MVAAKARRNAAKNKYAHLKWPNCTPEDIAKTEMLIWPMRFGHVCPASDGASCVIYASEDA 238

Query: 224 AKELGIPKDKWV--------EIAGMGRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVE 275
            K LGI +  WV        E A  G +     + +  D      A ++A KAY+ A ++
Sbjct: 239 VKRLGIKEVAWVKGVAAYADEEADQGESYQGTAVVDYSDQT---GAILSARKAYERAGIK 295

Query: 276 P--KDIDFFEVHDAFTVMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKAR 333
              K+ID  E++  F     +  E LG  + G   K  +EG   IDGD+PI   GG+ A 
Sbjct: 296 DPRKEIDVAEIYAPFPHQELMFSERLGFFDDGTAWKAVEEGVTEIDGDFPICPSGGVNAT 355

Query: 334 GHPVGATGVYQTVESVLQIRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTIL 385
            + +G++G+ + VE+ LQI G+A       D    +    GG     TV +L
Sbjct: 356 -NAIGSSGMQRVVEAALQIMGKAEEHQVPKDVRNAVAHAWGGQVQFNTVMVL 406


>emb|CAA64718.1| (X95443) sterol carrier protein x-related thiolase [Drosophila
           melanogaster]
           Length = 414
           
 Score =  138 bits (343), Expect = 1e-31
 Identities = 112/397 (28%), Positives = 175/397 (43%), Gaps = 24/397 (6%)

Query: 6   IVGVGMTPVGEHWRTS---LRDLAVEAILKAMDDAGIDKVDSLYVGNMASGSFVEQENLG 62
           +VGVGMT   +  R +     D A EAI KA+ DAGI   +   V    +G        G
Sbjct: 8   VVGVGMTKFEKPGRRADVCYPDFAREAITKALQDAGIKYEE---VQQAVAGYVYGDSTCG 64

Query: 63  ALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDAT 122
                  G+  IP   V   C++G +A+    + V SG  D VL +G EKM     S ++
Sbjct: 65  QRAIYEVGMTGIPVYNVNNNCSTGSSALYLAKQIVESGNADCVLALGFEKMERG--SLSS 122

Query: 123 RYLAYASDAEWELFHGVSFVALNALIM---------RHYMNTYGYTEEDLALFAVNAHAN 173
           +Y   A+  E  +        + A  M         + +M  YG   E     A   H +
Sbjct: 123 KYFDRANPMERHITEMGELAEIGAGPMAAQIFGNAGKEHMKKYGTKPEHFGKIAWKNHKH 182

Query: 174 GAKNPYAMFKRPITVETVMKSPYIADP-LKLFDASPVCDGAAAVIITIPEKAKELGIPKD 232
              N Y+ F+   T+E +MKSP + +  L      P  DG+ A I+      +  G+ K 
Sbjct: 183 TVNNRYSQFRDEYTLEQIMKSPQVVEGVLTKLQCCPTSDGSGAAILASEAFVRRNGLEKQ 242

Query: 233 KWVEIAGMGRAIDTINLANREDLLTLKAA---KIAAEKAYKMAKVEPKDIDFFEVHDAFT 289
             VEI GM  A D  +    + L+ +      ++A E+ +  +   P+   ++    A  
Sbjct: 243 A-VEIVGMEMASDPASTFADKSLMKIAGTDMTRLATERLFAKSGTSPRMSRWWNCTIASR 301

Query: 290 VMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESV 349
               ++ EALG+  +G+  +    G     G + +   GGL ++GHP+GATG+ Q  E  
Sbjct: 302 ANDLITYEALGLCGEGKAGEFIDAGDNTYGGKFVVNPSGGLISKGHPLGATGLAQCAELC 361

Query: 350 LQIRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTILR 386
            Q+RG A    QVP+A++ L  N+ G G  + V + R
Sbjct: 362 WQLRGLAEKR-QVPNAQLALQHNL-GLGGAVVVALYR 396


>pir||E70676 probable nonspecific lipid-transfer protein Rv3540c - Mycobacterium
           tuberculosis (strain H37RV) >gi|1666120|emb|CAB05038.1|
           (Z82098) ltp2 [Mycobacterium tuberculosis]
           Length = 386
           
 Score =  135 bits (336), Expect = 1e-30
 Identities = 110/366 (30%), Positives = 167/366 (45%), Gaps = 20/366 (5%)

Query: 6   IVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVDSLYVGNMASGSFVEQENLGALI 65
           IVG+G T   ++   S   LA EA+L A+ DAG+   D   V  + +  F    N    +
Sbjct: 8   IVGIGATDFSKNSGRSELRLAAEAVLDALADAGLSPTD---VDGLTT--FTMDTNTEIAV 62

Query: 66  ADWAGLGNIPAV-KVEAACASGGAAVQEGAKAVLSGLEDVVLVVGV--EKMTDAWPSDAT 122
           A  AG+G +    K+     +  A VQ  A AV +G+ DVV+      E+    +    T
Sbjct: 63  ARAAGIGELTFFSKIHYGGGAACATVQHAAMAVATGVADVVVAYRAFNERSGMRFGQVQT 122

Query: 123 RYLAYAS----DAEWELFHGVSFVALN-ALIMRHYMNTYGYTEEDLALFAVNAHANGAKN 177
           R    A     D  +   HG+S  A   A+I R YM+  G T  D    +V    + A N
Sbjct: 123 RLTENADSTGVDNSFSYPHGLSTPAAQVAMIARRYMHLSGATSRDFGAVSVADRKHAANN 182

Query: 178 PYAMFK-RPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVE 236
           P A F  +PIT+E    S +IA+PL+L D     DGA A+++T   +A++L   +   +E
Sbjct: 183 PKAYFYGKPITIEDHQNSRWIAEPLRLLDCCQETDGAVAIVVTSAARARDLK-QRPVVIE 241

Query: 237 IAGMGRAIDTINLAN--REDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAAL 294
            A  G + D   + +  R +L  L    +   + +  + + P D+    ++D FT    +
Sbjct: 242 AAAQGCSPDQYTMVSYYRPELDGLPEMGLVGRQLWAQSGLTPADVQTAVLYDHFTPFTLI 301

Query: 295 SLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRG 354
            LE LG   KGE      +G I + G  PI T GG     +  G  G+    E V Q+RG
Sbjct: 302 QLEELGFCGKGEAKDFIADGAIEVGGRLPINTHGGQLGEAYIHGMNGI---AEGVRQLRG 358

Query: 355 EAPNGI 360
            + N +
Sbjct: 359 TSVNPV 364


>pir||A83518 hypothetical protein PA1016 [imported] - Pseudomonas aeruginosa
           (strain PAO1) >gi|9946927|gb|AAG04405.1|AE004534_3
           (AE004534) hypothetical protein [Pseudomonas aeruginosa]
           Length = 383
           
 Score =  132 bits (329), Expect = 6e-30
 Identities = 115/395 (29%), Positives = 183/395 (46%), Gaps = 37/395 (9%)

Query: 3   KPIIVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGI--DKVDSLYVGNMASG----SFV 56
           K  IVG+G   VGE    S  +L  +A LKA+ DAG+    +D+++    +      S  
Sbjct: 8   KTAIVGIGSAGVGEAPGYSAIELLGQASLKAIADAGLKLSDIDAIFAATSSHAFPTLSVA 67

Query: 57  EQENLGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVV-GVEKMTD 115
           E   +     D   +G           +S    + +   A+ +GL D  L+  G  + T 
Sbjct: 68  EYLGIRPKFVDGTNIGG----------SSFELHLLQATLALEAGLCDAALICYGSNQRT- 116

Query: 116 AWPSDATRYLAYASDAEWELFHGVSF-----VALNALIMRHYMNTYGYTEEDLALFAVNA 170
                A   L   S+ +W   H   +     +   AL    +M+ YG T E LA  AV+A
Sbjct: 117 -----AGGRLVSMSEPQW---HETPYKPRHPITAYALAASRHMHQYGTTREQLAEVAVSA 168

Query: 171 HANGAKNPYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIP 230
                 NP A  + P++V+ V+ +  ++DPL   D   V DG  A ++   E+A++L   
Sbjct: 169 RQWANLNPEAFARGPLSVDDVLAARMVSDPLSAADCCLVTDGGGACVVVRAERARDLPNA 228

Query: 231 KDKWVEIAGMGRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTV 290
              ++  AG       +++ +    LT+ AA  +A +A +MA V   DID   ++DAFT+
Sbjct: 229 PVYFLGAAGAQWHRSIVSMPD----LTVTAASESAPRAMQMAGVRHADIDLVMLYDAFTI 284

Query: 291 MAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVL 350
              L LE LG   KGEG    + G+IA  G+  + T GG  +  HP G  G++  +E+V 
Sbjct: 285 NTLLFLEDLGFCAKGEGGPFVQGGRIAPGGELAVNTNGGGLSCVHP-GMYGMFLIIEAVT 343

Query: 351 QIRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTIL 385
           Q+R +A    Q+  A++ L    GGT S+    +L
Sbjct: 344 QLRRQAGER-QLAKADVALLHGNGGTLSSQVTALL 377


>pir||D70674 probable lipid carrier protein - Mycobacterium tuberculosis
           (strain H37RV) >gi|1666137|emb|CAB05053.1| (Z82098)
           hypothetical protein Rv3523 [Mycobacterium tuberculosis]
           Length = 394
           
 Score =  125 bits (311), Expect = 8e-28
 Identities = 116/385 (30%), Positives = 178/385 (46%), Gaps = 33/385 (8%)

Query: 6   IVGVGMTP-VGEHWRTSLRDLAVEAILKAMDDAG--IDKVDSLYVGNMASGSFVEQENLG 62
           ++G G T  V +    S+  L  EAI +A+ D+G   D +D++ VG   +  F E   + 
Sbjct: 8   VLGTGQTKYVAKRQDVSMNGLVREAIDRALADSGSTFDDIDAVVVGK--APDFFEGVMMP 65

Query: 63  AL-IADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDA 121
            L +AD  G    P ++V  A + GG+     A  V SG    VL +  EK ++      
Sbjct: 66  ELFMADAMGATGKPLIRVHTAGSVGGSTGVVAASLVQSGKYRRVLALAWEKQSE------ 119

Query: 122 TRYLAYASDAEWELFHGVSFV--------ALNALIMRHYMNTYGYTEEDLALFAVNAHAN 173
                  S+A W L   V F            A  +R Y+   G      A+ AV    N
Sbjct: 120 -------SNAMWALSIPVPFTKPVGAGAGGYFAPHVRAYIRRSGAPAHIGAMVAVKDRLN 172

Query: 174 GAKNPYAMFKRP-ITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKD 232
           G++NP A  ++P IT+E VM S  + DP++  +  P  DGA AV++   E A        
Sbjct: 173 GSRNPLAHLQQPDITLEKVMASQMLWDPIRFDETCPSSDGACAVVVGDEEIADARLAQGH 232

Query: 233 KWVEIAGMGRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPK--DIDFFEVHDAFTV 290
               I G     + +  A R D +  +A + AA   +K A +     +ID  E++  F+ 
Sbjct: 233 PVAWIHGTALRTEPLAFAGR-DQVNPQAGRDAAAALWKAAGITSPIDEIDAAEIYVPFSW 291

Query: 291 MAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVL 350
              + LE LG A +GEG KL + G+ AI G  P+   GG+ +  +P+GA+G+ +  E+ +
Sbjct: 292 FEPMWLENLGFAREGEGWKLTEAGETAIGGRLPVNPSGGVLS-ANPIGASGLIRFAEAAI 350

Query: 351 QIRGEAPNGIQVPDAEIGLTQNIGG 375
           Q+ G+A    QVP A   L    GG
Sbjct: 351 QVMGKA-EARQVPGARKALGHAYGG 374


>gb|AAB48108.1| (U41818) PhlC [Pseudomonas fluorescens]
           Length = 398
           
 Score =  125 bits (311), Expect = 8e-28
 Identities = 112/407 (27%), Positives = 173/407 (41%), Gaps = 62/407 (15%)

Query: 13  PVGEHWRTSLRDLAVEAILKAMDDAGIDKVDSLYVGNMASGSFV-EQENLGALIADWAGL 71
           P     R + +++ VE+  +A++   +   +   V     G  + E   LG  I+D  G+
Sbjct: 17  PGSSRVRQTFKEMIVESAYQALNAIKMHPRELQAVAYGYHGEGISEYGGLGPTISDALGI 76

Query: 72  GNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDATRYLAYASDA 131
              P     A C S   + Q   + V SG  D+VL  G EKMTD +  +   Y+  +++ 
Sbjct: 77  SPAPTFMSTANCTSSSVSFQMAHQMVASGEYDIVLCGGFEKMTDHF--NYAEYIGSSTEC 134

Query: 132 EWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFA-------VNAHANGAKNPYAMFKR 184
           E++ F G+S     AL    Y   +GY   +  + A       + AH       Y +   
Sbjct: 135 EYDYFLGISHTDAFALATAEYFEKFGYAGREADVLATFGRQMRIYAHNTPTATRYGV--- 191

Query: 185 PI-TVETVMKSPYIADPLKLFDASP----VCDGAAAVIITIP------------------ 221
           P+ ++ET+  S      L   +AS     V +  A    T P                  
Sbjct: 192 PVPSLETLKNSEACGSMLAWGEASGCAILVAEHLAHRYTTQPVFVRGCAYTGVSHYFGTR 251

Query: 222 ---EKAKELGIPKDKWVEIAGMGRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKD 278
                 K  G+PKD       +G A+   ++A              AE AYK A +  KD
Sbjct: 252 YHNPTLKYPGLPKD-------VGMAVSANSIA-------------CAEIAYKKAGITAKD 291

Query: 279 IDFFEVHDAFTVMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVG 338
           ID  +V+D       + +E++GV   G+      EG IA+DG  P+ T GG   RGH  G
Sbjct: 292 IDVAQVYDLLGA-GLIQMESMGVCGPGQAGDFVLEGGIALDGQLPLNTDGGNIGRGHASG 350

Query: 339 ATGVYQTVESVLQIRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTIL 385
             G+    E   Q+RGE+ N  QV DA IG++QN+GG  ++ +V +L
Sbjct: 351 CDGILHITELFRQLRGESNN--QVKDARIGVSQNLGGYAAHNSVIVL 395


>pir||B70582 probable lipid-transfer protein - Mycobacterium tuberculosis
           (strain H37RV) >gi|2078063|emb|CAB08512.1| (Z95210)
           hypothetical protein Rv0914c [Mycobacterium
           tuberculosis]
           Length = 412
           
 Score =  123 bits (306), Expect = 3e-27
 Identities = 112/376 (29%), Positives = 164/376 (42%), Gaps = 29/376 (7%)

Query: 24  DLAVEAILKAMDDAGIDKVDS-----LYVGNMASGSFVEQENLGALIADWAG-LGNIPAV 77
           DL  E +   +  A +D  D      ++V N     F  Q +LGA+ A     L + PA 
Sbjct: 28  DLTREVVDGTLTAAKVDAADLAAAGVVHVANAFGEMFARQGHLGAMPATVCDDLWDTPAT 87

Query: 78  KVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDATRYLAYASDAEWELFH 137
           + EAACASG  A       + SG   V LVVG+E +    P D      + S A W    
Sbjct: 88  RHEAACASGSVATLAAMADLRSGAYRVALVVGLE-LEKTVPGDTAA--EHLSAAAWTGHE 144

Query: 138 GVS----FVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYAMFKR-----PITV 188
           G      + ++ A +   Y   YG  +  L   A    AN  +NP A  +      PIT 
Sbjct: 145 GAEARYLWPSMFAQVADEYDRRYGLDDTHLRAIAQLNFANARRNPNAQTRGWTIPDPITD 204

Query: 189 ETVMKSPYIADPLKLFDASPVCDGAAAVIITIP------EKAKELGIPKDKWVEIAGMG- 241
           +    +P     L+ FD S + DG A +++           A+ +G          G+G 
Sbjct: 205 DDAT-NPLTEGRLRRFDCSQMTDGGAGLVLVSDAYLRDHRDARPIGRIDGWGHRTVGLGL 263

Query: 242 -RAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALG 300
            + +D +   +    L L   +     A + A+V   D+D  EVHD FT    L+++ +G
Sbjct: 264 RQKLDRVAQGDSAPYL-LPHVRATVLDALRRARVTLDDLDGIEVHDCFTPSEYLAIDHIG 322

Query: 301 VAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGI 360
           +   GE  K  + G+I I G  PI   GGL   GHPVGA+GV   +++  Q+ G A    
Sbjct: 323 LTGPGESWKAIENGEIEIGGRLPINPSGGLIGGGHPVGASGVRMLLDAAKQVSGIA-GDY 381

Query: 361 QVPDAEIGLTQNIGGT 376
           QV +AE   T N GG+
Sbjct: 382 QVENAEAFGTLNFGGS 397


>gi|11498573 3-ketoacyl-CoA thiolase (acaB-10) [Archaeoglobus fulgidus]
           >gi|7450470|pir||H69370 3-ketoacyl-CoA thiolase
           (acaB-10) homolog - Archaeoglobus fulgidus
           >gi|2649632|gb|AAB90275.1| (AE001038) 3-ketoacyl-CoA
           thiolase (acaB-10) [Archaeoglobus fulgidus]
           Length = 388
           
 Score =  123 bits (305), Expect = 4e-27
 Identities = 115/366 (31%), Positives = 170/366 (46%), Gaps = 37/366 (10%)

Query: 21  SLRDLAVEAILKAMDDAGIDK---VDS-------LYVGNMASGSFVEQENLGALIADWAG 70
           S +++  EA ++A  DAGI+    VDS       +Y G      FV  + LGA++     
Sbjct: 28  SWKEIMYEAAVRAYTDAGINPRRDVDSFVTCAEDIYEGFAIFDEFVPDQ-LGAVVK---- 82

Query: 71  LGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDATRYLAYASD 130
               P   V A    G A        + SGL D+ +V    K +D         + +A D
Sbjct: 83  ----PTCTVTADFLYGVATAY---MHINSGLADIAVVEAHSKASDI--QTFGNVVKFAMD 133

Query: 131 AEWELFHGVSF-VALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYAMFKRPITVE 189
             W    G +    L AL M  YM     +EED+A   V    N   NP A +   +T++
Sbjct: 134 PIWLRNVGNAHPYYLAALEMFQYMAERCLSEEDVARVVVKNKNNALLNPAAPYAANVTLD 193

Query: 190 TVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMGRAIDTI-- 247
            VM SP + DP+K  + +P+ DG    ++   E A++L    D  V + G+G   +T   
Sbjct: 194 DVMASPKLFDPMKKMEIAPLADGCVVFVLASDEVARKL---TDNPVWVKGIGWWSETYGY 250

Query: 248 NLANREDLLTLKAAKIAAEKAYKMAKVE--PKDIDFFEVHDAFTVMAALSLEALGVAEKG 305
           + A+   +   KAAK+A    YKMA +    K++DF EV D F       +EAL +A K 
Sbjct: 251 DTASFSAMYAYKAAKMA----YKMAGIANPAKEVDFAEVDDRFAFKEMQHIEALQLAGKF 306

Query: 306 EGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGIQVPDA 365
           + A+L  EG    DG  P+   GG    G+ +  TG  + +E VLQ+RGEA    Q+ D 
Sbjct: 307 DVARLMAEGYFDRDGAKPVNVSGGSLGVGNLLECTGGQKALEVVLQLRGEAGKR-QLSDV 365

Query: 366 EIGLTQ 371
           E+G+ Q
Sbjct: 366 EVGVAQ 371


>pir||T50937 DitF protein [imported] - Pseudomonas abietaniphila
           >gi|4455077|gb|AAD21068.1| (AF119621) DitF [Pseudomonas
           abietaniphila]
           Length = 397
           
 Score =  113 bits (281), Expect = 3e-24
 Identities = 104/395 (26%), Positives = 173/395 (43%), Gaps = 35/395 (8%)

Query: 6   IVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDKVD----SLYVGNMASGSFVEQENL 61
           I G+G + VG     S   L +EA L+A+ DAG+ + D    + + G+  +G        
Sbjct: 13  ITGIGQSEVGRPSSKSAMRLTLEACLEAIADAGLTREDIDGVACWPGDNNNGDPFSPVGP 72

Query: 62  GALIA------DWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTD 115
            AL +      +W G G      +        A V  GA A+ +GL   VLV        
Sbjct: 73  SALKSALGLNVNWFGAGYEGPGPL--------AGVINGAMAIAAGLCRHVLVFRTITEAS 124

Query: 116 AWPSD------ATRYLAYASDAEWELFHGV---SFVALNALIMRHYMNTYGYTEEDLALF 166
           A   +      + +     S   W+ F      S + L AL  + + + YG   E LA  
Sbjct: 125 ARQHNKQAGALSAKTQGRDSSHAWQWFTPFNVHSGINLMALYAQRHFHEYGTRPEQLAQI 184

Query: 167 AVNAHANGAKNPYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKE 226
           A+   AN  +NP A+++ P+T++  M S  I+ PL++FD    CD + A++++  + AK+
Sbjct: 185 ALTCRANAQRNPKAIYRTPMTMDDYMASRMISSPLRMFDCDVHCDASTAIVLSRRDVAKD 244

Query: 227 LGIPKDKWVEIAGMGRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHD 286
               + + + I  MG A+D    +  +  LT  AA       +      P D+   +++D
Sbjct: 245 ---TRHQPIRIEAMGAALDQ-PWSWDQISLTQMAAFDVGRMMWARTDYTPSDVGSAQLYD 300

Query: 287 AFTVMAALSLEALGVAEKGEGAKLAKEGQ-IAIDGDYPIQTMGGLKARGHPVGATGVYQT 345
            F+++  + LEALG+   G+     + G+ IA+ G  PI T GG  + G   G   V+  
Sbjct: 301 GFSILTMIWLEALGLCSTGQSGAFVEGGERIALTGQLPINTNGGQLSGGRTHGLGYVH-- 358

Query: 346 VESVLQIRGEAPNGIQVPDAEIGLTQNIGGTGSNI 380
            E+ LQ+ G A      P     +    G  G ++
Sbjct: 359 -EACLQLWGRAEGRQTRPHTVAAVAAGGGPLGGSL 392


>gb|AAK42245.1| Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) (acaB-2)
           [Sulfolobus solfataricus]
           Length = 381
           
 Score =  107 bits (264), Expect = 3e-22
 Identities = 104/355 (29%), Positives = 159/355 (44%), Gaps = 42/355 (11%)

Query: 21  SLRDLAVEAILKAMDDAG-----------IDKVDSLYVGNMASGSFVEQENLGALIADWA 69
           S R++  EA  +A  DAG           I   +  + G   +  F   +  GA+     
Sbjct: 26  SFREMVFEAASRAYKDAGGINPRSDVDSFISCQEDFWEGISIADEFAPDQMGGAMR---- 81

Query: 70  GLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWP-SDATRYLA-- 126
                P + V      G A     A  + SG+ +VV +    K++D    SD  ++    
Sbjct: 82  -----PTMTVAGDSLQGLA---HAAMHINSGVANVVSIEAHSKVSDILTFSDLEKFAMDP 133

Query: 127 -YASDAEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYAMFKRP 185
            Y        FH ++   L+A+    +M+  G T EDLAL        G  +P A F   
Sbjct: 134 IYIRSINPPNFHFIA--GLDAV---KFMHRKGITREDLALVVEKNKKAGLSSPRASFASN 188

Query: 186 ITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMGRAID 245
           I+   VMK  Y+  PL   D +P  DGA  +++   E AK+L   KD ++ + G+G A D
Sbjct: 189 ISAVDVMKKNYVVYPLSELDIAPFVDGAIVIVVADEEVAKKL--KKDDYLVVKGIGFATD 246

Query: 246 TINLANREDLLTLKAAKIAAEKAYKMAKVEP--KDIDFFEVHDAFTVMAALSLEALGVAE 303
           + NL   E L      KIA++ AYKMA VE   +  D   V D ++      LE L V+E
Sbjct: 247 SSNLETAE-LGKANYMKIASDMAYKMAGVETPRRYFDAVFVDDRYSYKELQHLEGLRVSE 305

Query: 304 KGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATG---VYQTVESVLQIRGE 355
             E +K  +EG  +  G+ P+  +GG  A+G P+ A+G   +   +E + Q +GE
Sbjct: 306 --EPSKDLREGNFSPQGEVPVNPLGGHMAKGVPLEASGFSLLLDAIEYIKQGKGE 358


>gb|AAK43216.1| Acetyl-CoA c-acetyltransferase (acetoacetyl-CoA thiolase) (acaB-10)
           [Sulfolobus solfataricus]
           Length = 385
           
 Score =  106 bits (263), Expect = 3e-22
 Identities = 93/375 (24%), Positives = 168/375 (44%), Gaps = 26/375 (6%)

Query: 24  DLAVEAILKAMDDAGIDK--VDSLYVGNMAS--GSFVEQENLGALIADWAGLGNIPAVKV 79
           +L  + +  A++ AG+DK  VD +Y+  +      +         +A + G+        
Sbjct: 19  ELLADTVFSALEMAGLDKNYVDGIYLTYLPGTFDGYANSHFFTNQVAQYLGIRPKFTQIF 78

Query: 80  EAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDAT------RYLAYASDAEW 133
           +   AS  + +    KA+ +G  + +L +   K T+      T       Y   +     
Sbjct: 79  DYGGASALSMIHRAYKAIKAGEGETILCIVGGKATELRNKGVTVDAIDKAYPNVSLTPFD 138

Query: 134 ELFHGVSF---VALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYAMFKRPITVET 190
            LF G++    V+  AL+   +   +  T+E  AL AV    N  +N  AMFK P+T+E 
Sbjct: 139 RLFRGLNDLNPVSDYALVANRHKYLFKSTDEQRALIAVRQRFNAMQNSKAMFKDPLTIEQ 198

Query: 191 VMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMGRAIDTINLA 250
           V+KSP ++ PL L +     DG    +++  +++ +  +     ++I G G A       
Sbjct: 199 VLKSPLVSYPLHLLEIVYPIDGFHVFVVS--KRSSKSALTN---IDILGYGEAHWPFMPT 253

Query: 251 NREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALGVAEKGEGAKL 310
             ++++   A  + + K     +     ID FE++D+FT+   L +E +G+AEKG+G   
Sbjct: 254 ELDEIVYTPA--VESSKGLLNGR-----IDAFELYDSFTITVMLQVEDIGLAEKGKGGSF 306

Query: 311 AKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGIQVPDAEIGLT 370
            +       GD PI T GG    G P   +G     E++LQ+   A +G QV   ++   
Sbjct: 307 FENHDTTFKGDVPINTGGGSLNTGQPAYMSGGVILEEALLQLNDMA-DGHQVKGTDVVFL 365

Query: 371 QNIGGTGSNITVTIL 385
             IGG   + +V+++
Sbjct: 366 NGIGGWNRSHSVSLV 380


>gb|AAK42641.1| Acetyl-CoA c-acetyltransferase (acetoacetyl-CoA thiolase) (acaB-6)
           [Sulfolobus solfataricus]
           Length = 380
           
 Score =  106 bits (262), Expect = 5e-22
 Identities = 92/368 (25%), Positives = 168/368 (45%), Gaps = 17/368 (4%)

Query: 24  DLAVEAILKAMDDAGIDKVD-SLYVGNMASGSFVEQE---NLGALIADWAGLGNIPAVKV 79
           +L  E   +A+D AG++  D    + N+  GSF       N  A I+++ G+       V
Sbjct: 19  ELLKEVTDEALDIAGLNYADVDGIMANIGRGSFHGNRTYLNPPAQISEYFGIKPKIIEHV 78

Query: 80  EAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPS--DATRYLAYASDAEWELFH 137
           +    S  + +    KA+ +G  + +L +   K++    +    T  +    D   +++ 
Sbjct: 79  QYGGPSVLSMIYRAYKAIKAGDAETILCIQGGKISHLRDNHFQKTDIIDSPFDEYIKIYD 138

Query: 138 GVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYAMFKRPITVETVMKSPYI 197
            +S ++  A++   +   +G T+E  A  AV    N + NP A+F+ PITVE V+KS  +
Sbjct: 139 QMSPISDYAMVAYRHSKLFGTTDEQRARIAVIQRYNASYNPKALFRNPITVEDVLKSRIV 198

Query: 198 ADPLKLFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMGRAIDTINLANREDLLT 257
           + PL L +     DG    +++       L     + ++I   G A      A  +D++ 
Sbjct: 199 SYPLHLLEIVYPIDGFHVFVVSKRSSKSAL-----RNIDILAYGEAHWPNPPAEWDDIIY 253

Query: 258 LKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALGVAEKGEGAKLAKEGQIA 317
               + A   ++ + +V     D F+++D+FT+   L +E +G+ EKG+  +  +   ++
Sbjct: 254 TPTTESAKRASFDLNRV-----DAFQLYDSFTITVMLQMEDIGLVEKGKVGQFVESHDLS 308

Query: 318 IDGDYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGIQVPDAEIGLTQNIGGTG 377
             GD PI T GG    G P   +G     E++LQ+   A NG QV  A +     IG   
Sbjct: 309 FKGDVPINTGGGSLNTGQPAYMSGGVILEEALLQLNDMA-NGHQVKGANVIFLNGIGWWS 367

Query: 378 SNITVTIL 385
              +VT++
Sbjct: 368 RRHSVTLV 375


>gi|4506823 sterol carrier protein 2 [Homo sapiens] >gi|432977|gb|AAA03558.1|
           (M75884) sterol carrier protein-2 [Homo sapiens]
           Length = 289
           
 Score = 97.1 bits (238), Expect = 3e-19
 Identities = 52/126 (41%), Positives = 74/126 (58%), Gaps = 2/126 (1%)

Query: 261 AKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALGVAEKGEGAKLAKEGQIAIDG 320
           +K AA K Y+ + + P DID  E+HD F+    L+ EALG+  +G+GA L   G     G
Sbjct: 23  SKEAARKCYEKSGLTPNDIDVIELHDCFSTNELLTYEALGLCPEGQGATLVDRGDNTYGG 82

Query: 321 DYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGIQVPDAEIGLTQNIGGTGSNI 380
            + I   GGL ++GHP+GATG+ Q  E   Q+RGEA    QVP A++ L  N+ G G  +
Sbjct: 83  KWVINPSGGLISKGHPLGATGLAQCAELCWQLRGEAGKR-QVPGAKVALQHNL-GIGGAV 140

Query: 381 TVTILR 386
            VT+ +
Sbjct: 141 VVTLYK 146


>gb|AAA42120.1| (M34728) sterol carrier protein-2 (SCP-2) [Rattus norvegicus]
           Length = 273
           
 Score = 94.4 bits (231), Expect = 2e-18
 Identities = 51/126 (40%), Positives = 72/126 (56%), Gaps = 2/126 (1%)

Query: 261 AKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALGVAEKGEGAKLAKEGQIAIDG 320
           +K AA K Y+ + + P D+D  E+HD F+    L+ EALG+  +G+G  L   G     G
Sbjct: 7   SKEAARKCYEKSGLGPSDVDVIELHDCFSTNELLTYEALGLCPEGQGGALVDRGDNTYGG 66

Query: 321 DYPIQTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGIQVPDAEIGLTQNIGGTGSNI 380
            + I   GGL ++GHP+GATG+ Q  E   Q+RGEA    QVP A++ L  N+ G G   
Sbjct: 67  KWVINPSGGLISKGHPLGATGLAQCAELCWQLRGEAGKR-QVPGAKVALQHNL-GLGGAA 124

Query: 381 TVTILR 386
            VT+ R
Sbjct: 125 VVTLYR 130


>gi|11497817 3-ketoacyl-CoA thiolase (acaB-5) [Archaeoglobus fulgidus]
           >gi|7450483|pir||A69275 3-ketoacyl-CoA thiolase (acaB-5)
           homolog - Archaeoglobus fulgidus
           >gi|2650441|gb|AAB91030.1| (AE001092) 3-ketoacyl-CoA
           thiolase (acaB-5) [Archaeoglobus fulgidus]
           Length = 368
           
 Score = 93.2 bits (228), Expect = 4e-18
 Identities = 104/396 (26%), Positives = 162/396 (40%), Gaps = 63/396 (15%)

Query: 6   IVGVGMTPVGEHWRTSLRDLAVEAILKAMDDAGIDK--VDSLYVGNMASGSFVEQENLGA 63
           IVGVG +    H      ++A  A  +A++DAGI++  VDS  +G               
Sbjct: 18  IVGVGFSEFRIH-EEPFYNVAFLAAKRALEDAGIERGEVDSFILGGY------------- 63

Query: 64  LIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDATR 123
              D  G+G   +    A  A  GA ++   +      +D +  + +  M     S+ T 
Sbjct: 64  ---DNLGVGRTISNMYTAPAA--GAYLRHEIRVS----DDALFALPLAFMKVKSGSEITM 114

Query: 124 YLAYASDAEWEL-----------FH---GVSFVALNALIMRHYMNTYGYTEEDLALFAVN 169
            LA+   +E  +           FH    +S     A+    Y   YG  EE +A   V 
Sbjct: 115 LLAFGHSSETPIELVELQSLDPFFHRPFNLSLPVFFAMQSYAYRERYGVKEEKIAEVVVR 174

Query: 170 AHANGAKNPYAMFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKELGI 229
               GAKNP A  +  ++VE V+ S  ++ PL+  + +  CDG  A I+     A+ L  
Sbjct: 175 MREKGAKNPRAYIREKVSVEDVLSSEVVSSPLRRLEMAEWCDGCVAFILAEETVARRL-- 232

Query: 230 PKDKWVEIAGMGRAIDTINLANREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFT 289
             D  V ++G+G + +  N      L  L     +AE A+KM+  E KD++  E+ D   
Sbjct: 233 -SDSPVWVSGLGWSAE--NYYFDRSLHDLPFVAKSAEMAFKMSGKERKDVEALEISDLTA 289

Query: 290 VMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPIQTMGGLKARGHPVGATGVYQTVESV 349
               + LEALG AE G G +    G +   G       G L    +  G+TG +     V
Sbjct: 290 DYYCMILEALGFAETGRGWEF--NGDVNFSG-------GALCTNAY--GSTGAFLLASIV 338

Query: 350 LQIRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTIL 385
            +IR          + E G+ Q++ G      V IL
Sbjct: 339 ERIR--------KGEIECGMAQSMSGYAQKSCVAIL 366


>emb|CAC00412.1| (AL160371) possible thiolase [Leishmania major]
           Length = 393
           
 Score = 89.3 bits (218), Expect = 7e-17
 Identities = 103/401 (25%), Positives = 167/401 (40%), Gaps = 39/401 (9%)

Query: 12  TPVGEHWRTSLRDLAVEAILKAMDDAGIDKVDS---LYVGNMASGSFVEQENLGALIADW 68
           T +G   R+S+ DLA EA+ +A  +A I   D    +   +++SG F++   L       
Sbjct: 1   TAIGALKRSSI-DLAREAMERAFAEANIAAKDVGALIATPSLSSGHFMQAHYLATQFQLT 59

Query: 69  AGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDATRYLAYA 128
           A     PA+  +     G + +     A+        L V V   +DA  +  +   A  
Sbjct: 60  AAN---PAMLFKTVDTGGASPISSIGAALDFFRRMPGLNVAVVVSSDAVHTLPSSEFAKR 116

Query: 129 SD--------AEWELFHGVSFVALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYA 180
           S+        AE  + HG  F A      +  M  YG   E LA+  V   A   ++P A
Sbjct: 117 SNESVPSPYLAEPHIPHGYDFYA------QWQMKRYGLKREQLAMVPVLMSAMSVRHPDA 170

Query: 181 MFKRPITVETVMKSPYIADPLKLFDASPVCDGAAAVIITIPEKAKE---LGIPKDKWVEI 237
           M +R  ++E V+ +  IA    L + +   DGA A+++   E  K+    G    +   +
Sbjct: 171 MCRRRYSLEEVLGARQIAPVTNLPECARRADGAVAIVLAREEHYKQHLATGPLDGRRPYV 230

Query: 238 AGMGRAIDTINLANREDLLTLKAAKIAAEKAYKMAK-----VEPKDIDFFEVHDAFTVMA 292
            G+G A   +      + +T +    +  +A ++A      +   DIDFF ++D F +  
Sbjct: 231 LGVGEASGPLYPPATHEEVTPET--FSCHRAMRLAYEATGGLSTSDIDFFGLYDCFPICF 288

Query: 293 ALSLEALGVAEKGEGAKLAKE--------GQIAIDGDYPIQTMGGLKARGHPVGATGVYQ 344
             +LEA G+  +GEG ++ +E        G      ++PI T GGL   G P     +Y 
Sbjct: 289 IRALEAAGLCREGEGGQMVEEAYRRAVQHGGDVDPSEFPINTHGGLMCFGAPWEVPAMYN 348

Query: 345 TVESVLQIRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTIL 385
             E+V Q+ G+A      P     L    GG  S   V IL
Sbjct: 349 VAEAVAQLGGQAGPRQVHPTPRRALVYGNGGIFSASAVAIL 389


>pir||E72467 probable non specific lipid-transfer protein APE2382 - Aeropyrum
           pernix (strain K1) >gi|5106086|dbj|BAA81397.1|
           (AP000064) 360aa long hypothetical non specific
           lipid-transfer protein [Aeropyrum pernix]
           Length = 360
           
 Score = 81.5 bits (198), Expect = 1e-14
 Identities = 55/208 (26%), Positives = 96/208 (45%), Gaps = 5/208 (2%)

Query: 144 LNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYAMFKRPITVETVMKSPYIADPLKL 203
           +  L+   ++   G   E LA+ A      G  NP A    P+T+  V+ +  + DPL  
Sbjct: 117 IGGLMANAFLARTGLGREALAMVAAKNKNAGLSNPRASHAAPVTLGDVLSAKPVVDPLTG 176

Query: 204 FDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMGRAIDTINLANREDLLTLKAAKI 263
           +D +P  D A  +++   E A+ L      W+E  G      T +LA  +   ++ + ++
Sbjct: 177 YDIAPFSDAAIVMLVASEEAARRL-TDTPVWIEGVGWSTESGTGSLAWHQ-WDSMPSIRM 234

Query: 264 AAEKAYKMAKVEPKD---IDFFEVHDAFTVMAALSLEALGVAEKGEGAKLAKEGQIAIDG 320
           A + A  MA +  +      F E+ D ++ M  LS+E  G+A   E   + + G     G
Sbjct: 235 AVDMAKSMAGLSGRPQTFTSFAELEDRYSFMEILSMEEAGIAGPEEAYSMLEAGDTEPSG 294

Query: 321 DYPIQTMGGLKARGHPVGATGVYQTVES 348
           +YP+   GG  A G  + ATG ++ +E+
Sbjct: 295 NYPVNPSGGSLAAGVALEATGGFRVLEA 322


>dbj|BAB11319.1| (AB016886) acetoacyl-CoA-thiolase [Arabidopsis thaliana]
           Length = 415
           
 Score = 78.4 bits (190), Expect = 1e-13
 Identities = 95/391 (24%), Positives = 163/391 (41%), Gaps = 95/391 (24%)

Query: 6   IVGVGMTPVGEHW-------RTSLRDLAVEAILKAMDDAGIDK--VDSLYVGNMASGSFV 56
           +VGV  TP+G+          T L  +A++A LK    A +D   V+ ++ GN+ +    
Sbjct: 17  VVGVARTPIGDFLGSLSSLTATRLGSIAIQAALKR---AHVDPALVEEVFFGNVLTA--- 70

Query: 57  EQENLGALIADWAGLG-----NIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVGVE 111
              NLG   A  A LG     ++    +   CA+G  +V   ++++  GL D+V+  G+E
Sbjct: 71  ---NLGQAPARQAALGAGIPYSVICTTINKVCAAGMKSVMLASQSIQLGLNDIVVAGGME 127

Query: 112 KMTDA--WPSDATR---------YLAYASDAEWELFHGVSFVALNALIMRHYMNTYGYTE 160
            M++   +  DA R               D  W++++         +      + Y  T 
Sbjct: 128 SMSNVPKYLPDARRGSRLGHDTVVDGMMKDGLWDVYNDFGMGVCGEIC----ADQYRITR 183

Query: 161 EDLALFAVNAHANG--AKNP--YAMFKRPITVETVMKSPYIA----DPLKLFD------- 205
           E+   +A+ +   G  A+N   +A    P+ V T    P +     + L  FD       
Sbjct: 184 EEQDAYAIQSFERGIAAQNTQLFAWEIVPVEVSTGRGRPSVVIDKDEGLGKFDAAKLKKL 243

Query: 206 ---------------ASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMGRAIDTINLA 250
                          AS + DGAAA+++   EKA ELG+      +I G   A      A
Sbjct: 244 RPSFKEDGGSVTAGNASSISDGAAALVLVSGEKALELGL--HVIAKIRGYADA------A 295

Query: 251 NREDLLTLKAAKIAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALGVAEKGEGAKL 310
              +L T   A +A  KA K A ++   +D++E+++AF+V+A  + + LG+  +      
Sbjct: 296 QAPELFTTTPA-LAIPKAIKRAGLDASQVDYYEINEAFSVVALANQKLLGLDPE------ 348

Query: 311 AKEGQIAIDGDYPIQTMGGLKARGHPVGATG 341
                        +   GG  + GHP+G +G
Sbjct: 349 ------------RLNAHGGAVSLGHPLGCSG 367


>pir||D70808 probable regulatory protein - Mycobacterium tuberculosis  (strain
           H37RV) >gi|2924459|emb|CAA17759.1| (AL022022)
           hypothetical protein Rv3522 [Mycobacterium tuberculosis]
           Length = 354
           
 Score = 71.8 bits (173), Expect = 1e-11
 Identities = 85/342 (24%), Positives = 142/342 (40%), Gaps = 26/342 (7%)

Query: 24  DLAVEAILKAMDDAGIDKVDSLYVGNMASGSFVEQENLG-ALIADWAGLGNIPAVKVEAA 82
           ++ +    +  D+ GI K D   +G   SGS         + I+    +G +P +     
Sbjct: 28  EMLMPCFAQLYDELGITKAD---IGFWCSGSSDYLAGRAFSFISAIDSIGAVPPINESHV 84

Query: 83  CASGGAAVQEGAKAVLSGLEDVVLVVGVEKMTDAWPSDATRYLAYASDAEWELFHGVSFV 142
                 A+ E    +L+G  D  LV G  K +        R L+  +D           V
Sbjct: 85  EMDAAWALYEAYIKLLTGEVDTALVYGFGKSS---AGTLRRVLSRQTDPYTVAPLWPDSV 141

Query: 143 ALNALIMRHYMNTYGYTEEDLALFAVNAHANGAKNPYAMFKRPITVETVMKSPYIADPLK 202
           ++  L  R  +++  +T E +A  A ++  N  +      + PITV  ++  P+ ADPL+
Sbjct: 142 SMAGLQARLGLDSGKWTHEQMARVAFDSFTNARR--VDSVEPPITVGELLARPFFADPLR 199

Query: 203 LFDASPVCDGAAAVIITIPEKAKELGIPKDKWVEIAGMGRAIDTINLANREDLLTLKAAK 262
             D +P+ DGAAAV++    +A+EL   ++    I G+   I++  L  R D+    + K
Sbjct: 200 RHDIAPITDGAAAVVLAADNRAREL---RENPAWITGIEHRIESPALGAR-DITESPSTK 255

Query: 263 IAAEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALGVAEKGE----GAKLAKEGQIAI 318
           +AA+ A         DID  E+H  FT    +  EA+ +  K +    G  LA     A 
Sbjct: 256 LAAKIA---TGGHTGDIDVAEIHGPFTHQHLIVAEAIRIPGKTKVNPSGGPLAANPMFAA 312

Query: 319 D----GDYPIQTMGGLKAR--GHPVGATGVYQTVESVLQIRG 354
                G     T  G   R   H      + Q + +V++ RG
Sbjct: 313 GLERIGFAAQHTWDGSARRVLAHATSGPALQQNLVAVMEGRG 354


>gb|AAG17184.1|AF191029_2 (AF191029) FadA [Enterobacter cloacae]
           Length = 387
           
 Score = 71.0 bits (171), Expect = 2e-11
 Identities = 105/424 (24%), Positives = 173/424 (40%), Gaps = 73/424 (17%)

Query: 1   MEKPIIVGVGMTPVGEHWRTSLRDLAVEAILK-----------AMDDAGIDKVDSLYVGN 49
           MEK +IV    TP+G     + R++  E +             A+D A +D +    +  
Sbjct: 1   MEKVVIVDAIRTPMGRSKGGAFRNVRAEDLSAHLMRSLLARNPALDPAALDDIYWGCLHQ 60

Query: 50  MASGSFVEQENLGALIADWAGLGNIPAVKVEAACASGGAAVQEGAKAVLSGLEDVVLVVG 109
                F    N  +L+A+     ++PAV V   C S   A+ + A+ +++G     LV G
Sbjct: 61  TLEQGFNLARN-ASLLAEIPH--SVPAVTVNRLCGSSMQALHDAARMIMTGDAQACLVGG 117

Query: 110 VEKMTDAWPSDA-------TRYLAYAS-----DAEW-ELFHGVSFVALNALIMRHYMNTY 156
           VE M     S         +R +A A+      AE     HG+S    +A   R +   +
Sbjct: 118 VEHMGHVPMSHGVHFHPGMSRNVAKAAGMMGLTAEMLSRLHGISREMQDAFAARSHARAW 177

Query: 157 GYTEEDL---ALFAVNAH-ANGAKNPYA---MFKRPITVETVMKSPYIADP----LKLFD 205
             T+       +     H A+G    ++   + +   TVE +       DP    +    
Sbjct: 178 AATQSGAFKNEIIPTGGHDADGVLKQFSYDEVIRPETTVEALSTLRPAFDPVTGTVTAGT 237

Query: 206 ASPVCDGAAAVIITIPEKAKELGI-PKDKWVEIAGMGRAIDTINLANREDLLTLKAAKIA 264
           +S + DGAAA+++    +A+ELG+ P+ +   +A +G     +          + A+K+A
Sbjct: 238 SSALSDGAAAMLVMSESRARELGLTPRARVRSMAVVGCDPSIMGYG------PVPASKLA 291

Query: 265 AEKAYKMAKVEPKDIDFFEVHDAFTVMAALSLEALGVAEKGEGAKLAKEGQIAIDGDYPI 324
            +KA   A     DID FE+++AF       ++ LG+            GQI    D  I
Sbjct: 292 LKKAGLTA----SDIDLFEMNEAFAAQILPCIKDLGLM-----------GQI----DEKI 332

Query: 325 QTMGGLKARGHPVGATGVYQTVESVLQIRGEAPNGIQVPDAEIGLTQNIGGTGSNITVTI 384
              GG  A GHP+G +G   +   +  + G+        DA+ GL     G G  I  T+
Sbjct: 333 NLNGGAIALGHPLGCSGARISTTLINLMEGK--------DAQFGLATMCIGLGQGI-ATV 383

Query: 385 LRRV 388
             RV
Sbjct: 384 FERV 387


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.316    0.134    0.385 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 138531070
Number of Sequences: 2977
Number of extensions: 5588998
Number of successful extensions: 15332
Number of sequences better than 1.0e-10: 68
Number of HSP's better than  0.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 15095
Number of HSP's gapped (non-prelim): 76
length of query: 388
length of database: 189,106,746
effective HSP length: 58
effective length of query: 330
effective length of database: 154,394,500
effective search space: 50950185000
effective search space used: 50950185000
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.6 bits)
S2: 166 (69.1 bits)