BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB0922 (PAB0922) DE:GTP-BINDING PROTEIN HOMOLOG
         (355 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||F75050 GTP-binding protein homolog PAB0922 - Pyrococcus aby...   711  0.0
pir||F71109 probable GTP-binding protein - Pyrococcus horikoshii...   629  e-179
pir||G64482 hypothetical GTP-binding protein homolog - Methanoco...   223  2e-57
gb|AAK40894.1| GTP binding protein, hypothetical [Sulfolobus sol...   171  1e-41
emb|CAB57719.1| (Y18930) hypothetical gtp-binding protein [Sulfo...   171  1e-41
pir||E72764 probable GTP-binding protein APE0105 - Aeropyrum per...   167  2e-40
gb|AAF30346.1|AC019018_24 (AC019018) putative GTP-binding protei...   160  3e-38
gi|7019419 nucleolar GTPase [Homo sapiens] >gi|3334276|sp|Q13823...   151  1e-35
gi|11423270 nucleolar GTPase [Homo sapiens]                           151  1e-35
pir||T24970 hypothetical protein T19A6.2a - Caenorhabditis elega...   150  3e-35
pir||T24972 hypothetical protein T19A6.2b - Caenorhabditis elega...   150  3e-35
pir||T23172 hypothetical protein K01C8.9 - Caenorhabditis elegan...   149  5e-35
gb|AAB09043.1| (U69600) testicular antigen [Mus musculus]             148  1e-34
gb|AAF57834.1| (AE003802) CG6501 gene product [Drosophila melano...   147  2e-34
pir||T39037 hypothetical gtp-binding protein associated - fissio...   143  3e-33
gb|AAF27009.1|AC016827_20 (AC016827) putative GTPase [Arabidopsi...   143  4e-33
gi|6324381 Ynr053cp [Saccharomyces cerevisiae] >gi|1730685|sp|P5...   135  7e-31
gi|9506611 hypothetical protein [Homo sapiens] >gi|7022755|dbj|B...   122  7e-27
gb|AAF55384.1| (AE003716) CG3983 gene product [Drosophila melano...   119  4e-26
pir||T40020 probable protein transport protein - fission yeast  ...   119  6e-26
gi|7657048 putative nucleotide binding protein, estradiol-induce...   116  3e-25
gi|11435204 putative nucleotide binding protein, estradiol-induc...   116  4e-25
pir||B70180 conserved hypothetical protein BB0643 - Lyme disease...   114  1e-24
gi|6320842 Yer006wp [Saccharomyces cerevisiae] >gi|731436|sp|P40...   111  1e-23
pir||F69880 conserved hypothetical protein ylqF - Bacillus subti...   109  6e-23
dbj|BAA75361.1| (AB013365) YlqF [Bacillus halodurans] >gi|101750...   108  1e-22
pir||F72336 conserved hypothetical protein - Thermotoga maritima...   105  7e-22
sp|Q10190|YAWG_SCHPO HYPOTHETICAL GTP-BINDING PROTEIN C3F10.16C ...   105  7e-22
pir||E81941 hypothetical protein NMA0950 [imported] - Neisseria ...   104  2e-21
pir||C81165 conserved hypothetical protein NMB0739 [imported] - ...   104  2e-21
pir||E82449 conserved hypothetical protein VCA0528 [imported] - ...    96  6e-19
gi|6321339 Ygl099wp [Saccharomyces cerevisiae] >gi|1723894|sp|P5...    92  7e-18
gb|AAD15335.1| (AC004044) hypothetical protein [Arabidopsis thal...    91  2e-17
pir||S75087 hypothetical protein slr0267 - Synechocystis sp. (st...    89  6e-17
dbj|BAA92116.1| (AK002163) unnamed protein product [Homo sapiens]      72  1e-11
sp|O67749|ENGA_AQUAE PROBABLE GTP-BINDING PROTEIN ENGA >gi|74505...    71  1e-11
pir||S40612 myosin-related protein - slime mold (Physarum polyce...    69  6e-11
dbj|BAB14161.1| (AK022657) unnamed protein product [Homo sapiens]      69  6e-11
emb|CAB38462.1| (AL035632) /prediction=(method:""genefinder"", v...    69  8e-11

>pir||F75050 GTP-binding protein homolog PAB0922 - Pyrococcus abyssi  (strain
           Orsay) >gi|5458812|emb|CAB50299.1| (AJ248287)
           GTP-BINDING PROTEIN HOMOLOG [Pyrococcus abyssi]
           Length = 355
           
 Score =  711 bits (1816), Expect = 0.0
 Identities = 355/355 (100%), Positives = 355/355 (100%)

Query: 1   MKQKKAWRIVKEVIGEADIVVEVVDARDPIGTRNRKLERMVIESGKKLLIVMNKADLVPK 60
           MKQKKAWRIVKEVIGEADIVVEVVDARDPIGTRNRKLERMVIESGKKLLIVMNKADLVPK
Sbjct: 1   MKQKKAWRIVKEVIGEADIVVEVVDARDPIGTRNRKLERMVIESGKKLLIVMNKADLVPK 60

Query: 61  EWAEEYKKRSEIPVIFISARERKGTGILRKELKKMAKTIDKDKVKVALIGYPNVGKSTII 120
           EWAEEYKKRSEIPVIFISARERKGTGILRKELKKMAKTIDKDKVKVALIGYPNVGKSTII
Sbjct: 61  EWAEEYKKRSEIPVIFISARERKGTGILRKELKKMAKTIDKDKVKVALIGYPNVGKSTII 120

Query: 121 NVLKGKHAVGTAPIPGYTKGKHLIRLTKRLWLLDTPGVVPIDDFDELVIKGGFPADKIEE 180
           NVLKGKHAVGTAPIPGYTKGKHLIRLTKRLWLLDTPGVVPIDDFDELVIKGGFPADKIEE
Sbjct: 121 NVLKGKHAVGTAPIPGYTKGKHLIRLTKRLWLLDTPGVVPIDDFDELVIKGGFPADKIEE 180

Query: 181 PVKPALKLIRRILETRKEALTEKFDIREFRDEEDILRKIGERRGIIREGGEVDIEETARW 240
           PVKPALKLIRRILETRKEALTEKFDIREFRDEEDILRKIGERRGIIREGGEVDIEETARW
Sbjct: 181 PVKPALKLIRRILETRKEALTEKFDIREFRDEEDILRKIGERRGIIREGGEVDIEETARW 240

Query: 241 FLREWQTGRFTLFSNDEEKKEEYIESFGEILEVIKQENLTEPRIILWKFRDLLEEYVGSE 300
           FLREWQTGRFTLFSNDEEKKEEYIESFGEILEVIKQENLTEPRIILWKFRDLLEEYVGSE
Sbjct: 241 FLREWQTGRFTLFSNDEEKKEEYIESFGEILEVIKQENLTEPRIILWKFRDLLEEYVGSE 300

Query: 301 KRFGAIEVGDFTVAIATGFKKCPNAIKFIERITGKNVITSECFGKKWKGVVAILD 355
           KRFGAIEVGDFTVAIATGFKKCPNAIKFIERITGKNVITSECFGKKWKGVVAILD
Sbjct: 301 KRFGAIEVGDFTVAIATGFKKCPNAIKFIERITGKNVITSECFGKKWKGVVAILD 355


>pir||F71109 probable GTP-binding protein - Pyrococcus horikoshii
           >gi|3257053|dbj|BAA29736.1| (AP000003) 355aa long
           hypothetical GTP-binding protein [Pyrococcus horikoshii]
           Length = 355
           
 Score =  629 bits (1606), Expect = e-179
 Identities = 300/355 (84%), Positives = 340/355 (95%)

Query: 1   MKQKKAWRIVKEVIGEADIVVEVVDARDPIGTRNRKLERMVIESGKKLLIVMNKADLVPK 60
           MKQKKAW IVKEVI EADIVVEVVDARDPIGTRN+KLERMV+ESGKKLL+VMNKADLVPK
Sbjct: 1   MKQKKAWAIVKEVIEEADIVVEVVDARDPIGTRNKKLERMVLESGKKLLLVMNKADLVPK 60

Query: 61  EWAEEYKKRSEIPVIFISARERKGTGILRKELKKMAKTIDKDKVKVALIGYPNVGKSTII 120
           EWAEEYK++SEIPV+FISARERKGTGILR+ELKK+AK I+K++VKVALIGYPNVGKSTII
Sbjct: 61  EWAEEYKRKSEIPVVFISARERKGTGILRRELKKIAKMINKERVKVALIGYPNVGKSTII 120

Query: 121 NVLKGKHAVGTAPIPGYTKGKHLIRLTKRLWLLDTPGVVPIDDFDELVIKGGFPADKIEE 180
           NVLKGKH+VGTAPIPGYTKGK +IRLTK++WLLDTPGVVPIDDFDELVIKGGFPADKI E
Sbjct: 121 NVLKGKHSVGTAPIPGYTKGKQMIRLTKKIWLLDTPGVVPIDDFDELVIKGGFPADKIRE 180

Query: 181 PVKPALKLIRRILETRKEALTEKFDIREFRDEEDILRKIGERRGIIREGGEVDIEETARW 240
           PVKPALKLIRRILETRKEALTEKF+I EF DEEDILRKIGERRGIIREGG VDIEETARW
Sbjct: 181 PVKPALKLIRRILETRKEALTEKFNITEFEDEEDILRKIGERRGIIREGGVVDIEETARW 240

Query: 241 FLREWQTGRFTLFSNDEEKKEEYIESFGEILEVIKQENLTEPRIILWKFRDLLEEYVGSE 300
           FLREWQTGRFTLFS +E+++EEYIESF EILE+IK++NLT+PR+I+WKF ++LE+Y+G+E
Sbjct: 241 FLREWQTGRFTLFSTEEKREEEYIESFDEILEIIKEQNLTDPRMIIWKFGNILEDYLGAE 300

Query: 301 KRFGAIEVGDFTVAIATGFKKCPNAIKFIERITGKNVITSECFGKKWKGVVAILD 355
           +RFGAI+VG+F +AIATGFKKCPNAIKF+ERIT KN + +ECFGKKWKG+VAIL+
Sbjct: 301 RRFGAIKVGEFMIAIATGFKKCPNAIKFVERITRKNAVAAECFGKKWKGIVAILE 355


>pir||G64482 hypothetical GTP-binding protein homolog - Methanococcus jannaschii
           >gi|1592105|gb|AAB99472.1| (U67587) hypothetical
           GTP-binding protein (SP:P40010) [Methanococcus
           jannaschii]
           Length = 373
           
 Score =  223 bits (563), Expect = 2e-57
 Identities = 127/343 (37%), Positives = 203/343 (59%), Gaps = 4/343 (1%)

Query: 8   RIVKEVIGEADIVVEVVDARDPIGTRNRKLERMVIESGKKLLIVMNKADLVPKEWAEEYK 67
           +IV ++I E D+++ V+DARDP  TRNR+LE+ +   GKKL+ V+NKADLVPK+  E++K
Sbjct: 15  KIVNKIIDECDVILLVLDARDPEMTRNRELEKKIKAKGKKLIYVLNKADLVPKDILEKWK 74

Query: 68  KRSEIPVIFISARERKGTGILRKELKKMAKTIDKDKVKVALIGYPNVGKSTIINVLKGKH 127
           +      +F+SA+ R GT ILR+ +K+  K + K + KV ++GYPNVGKS+IIN L GK 
Sbjct: 75  EVFGENTVFVSAKRRLGTKILREMIKQSLKEMGKKEGKVGIVGYPNVGKSSIINALTGKR 134

Query: 128 AVGTAPIPGYTKGKHLIRLTKRLWLLDTPGVVPIDDFDELVIKGGFPADKIEEPVKPALK 187
              T  + G TKG+  +RLTK + L+DTPGV+ + D D+LVI G    +K+E P+ PALK
Sbjct: 135 KALTGSVAGLTKGEQWVRLTKNIKLMDTPGVLEMRDEDDLVISGALRLEKVENPIPPALK 194

Query: 188 LIRRILETRKEALTEKFDIREFRDEEDILRKIGERRGIIREGGEVDIEETARWFLREWQT 247
           ++ RI       + E F +     +E++L+KIG +R  + +GGEVD+  TA+  ++E+Q 
Sbjct: 195 ILSRINNFDNSIIKEYFGVDYEEVDEELLKKIGNKRSYLTKGGEVDLVRTAKTIIKEYQD 254

Query: 248 GRFTLFSNDEEK-KEEYIESFGEILEVIKQ-ENLTEPRIILWKFRDLLEEYVGSEKR-FG 304
           G+   +  D +K  ++       I + +K    + + ++I+   +D    Y   +K   G
Sbjct: 255 GKLNYYKVDLKKYGQDRERDISFITKYLKDFPFIEDAKMIVTHLKDFDGLYKKIKKPVLG 314

Query: 305 AIEVGDFTVAIATGFKKCPNAIKFIERI-TGKNVITSECFGKK 346
           + E+    V ++ G K      K +E +   +N+     FG K
Sbjct: 315 SEEIDGNIVVVSFGEKTKDACRKKVENLCRERNIEVLSKFGDK 357


>gb|AAK40894.1| GTP binding protein, hypothetical [Sulfolobus solfataricus]
           Length = 267
           
 Score =  171 bits (428), Expect = 1e-41
 Identities = 94/253 (37%), Positives = 154/253 (60%), Gaps = 12/253 (4%)

Query: 10  VKEVIGEADIVVEVVDARDPIGTRNRKLERMVIESGKKLLIVMNKADLVP----KEWAEE 65
           V ++I  +D+VVEV+DAR+P  TR++K+E +++++ K +L+V+NK DLVP    K W + 
Sbjct: 5   VIQLIKRSDLVVEVLDAREPSLTRSKKIEDIIVKNYKNILLVLNKGDLVPLWVLKAWKDY 64

Query: 66  YKKRSEIPVIFISARERKGTGILRKELKKMAKTIDKDKVKVALIGYPNVGKSTIINVLKG 125
           +K    I  +++SA    GT ILR  +K + K    +K  V  +GYP  GKS++IN LKG
Sbjct: 65  FKTEENIESVYVSATSHLGTKILRDTMKSLLK---GNKGIVVFVGYPKSGKSSVINALKG 121

Query: 126 KHAVGTAPIP---GYTKGKHLIRLTKRLWLLDTPGVVPIDDFDELVIKGGFPADKIEEPV 182
           +H+  T+  P   GYTK   L ++  +++  DTPGV+P D  +      G+ AD +E+PV
Sbjct: 122 RHSAQTSAHPLEYGYTKSIQLFKIDNKIYAWDTPGVIPPDGNELEKTIRGYNADLLEDPV 181

Query: 183 KPALKLIRRILETRKEALTEKFDIREFRDEEDILRKIGERRG-IIREGGEVDIEETARWF 241
           KPAL LI R++E  KE+L   + + +F +  ++L +I  RRG   +   E +I+  AR  
Sbjct: 182 KPALMLINRVIEFSKESLISVYKV-DFNNPYELLERIAIRRGWFYKSTKEPNIDMAARAV 240

Query: 242 LREWQTGRFTLFS 254
           +R++  G+   ++
Sbjct: 241 IRDYHEGKIAYYT 253


>emb|CAB57719.1| (Y18930) hypothetical gtp-binding protein [Sulfolobus solfataricus]
           Length = 267
           
 Score =  171 bits (428), Expect = 1e-41
 Identities = 94/253 (37%), Positives = 154/253 (60%), Gaps = 12/253 (4%)

Query: 10  VKEVIGEADIVVEVVDARDPIGTRNRKLERMVIESGKKLLIVMNKADLVP----KEWAEE 65
           V ++I  +D+VVEV+DAR+P  TR++K+E +++++ K +L+V+NK DLVP    K W + 
Sbjct: 5   VIQLIKRSDLVVEVLDAREPSLTRSKKIEDIIVKNYKNILLVLNKGDLVPLWVLKAWKDY 64

Query: 66  YKKRSEIPVIFISARERKGTGILRKELKKMAKTIDKDKVKVALIGYPNVGKSTIINVLKG 125
           +K    I  +++SA    GT ILR  +K + K    +K  V  +GYP  GKS++IN LKG
Sbjct: 65  FKTEENIESVYVSATSHLGTKILRDTMKSLLK---GNKGIVVFVGYPKSGKSSVINALKG 121

Query: 126 KHAVGTAPIP---GYTKGKHLIRLTKRLWLLDTPGVVPIDDFDELVIKGGFPADKIEEPV 182
           +H+  T+  P   GYTK   L ++  +++  DTPGV+P D  +      G+ AD +E+PV
Sbjct: 122 RHSAQTSAHPLEYGYTKSIQLFKIDNKIYAWDTPGVIPPDGNELEKTIRGYNADLLEDPV 181

Query: 183 KPALKLIRRILETRKEALTEKFDIREFRDEEDILRKIGERRG-IIREGGEVDIEETARWF 241
           KPAL LI R++E  KE+L   + + +F +  ++L +I  RRG   +   E +I+  AR  
Sbjct: 182 KPALMLINRVIEFSKESLISVYKV-DFNNPYELLERIAIRRGWFYKSTKEPNIDMAARAV 240

Query: 242 LREWQTGRFTLFS 254
           +R++  G+   ++
Sbjct: 241 IRDYHEGKIAYYT 253


>pir||E72764 probable GTP-binding protein APE0105 - Aeropyrum pernix  (strain
           K1) >gi|5103494|dbj|BAA79015.1| (AP000058) 263aa long
           hypothetical GTP-binding protein [Aeropyrum pernix]
           Length = 263
           
 Score =  167 bits (419), Expect = 2e-40
 Identities = 100/264 (37%), Positives = 153/264 (57%), Gaps = 13/264 (4%)

Query: 3   QKKAWRIVKEVIGEADIVVEVVDARDPIGTRNRKLERMVIESGKKLLIVMNKADLVPKEW 62
           Q  +WR++   I   D+VVEVVD RDP+ TR+R+ ERM     K+LLIV+NK+DLVP   
Sbjct: 2   QLASWRLLARTIKNVDVVVEVVDIRDPMVTRSRRAERMAEALDKRLLIVLNKSDLVPLRV 61

Query: 63  AEEYKKRSE---IPVIFISARERKGTGILRKELKKMAKTIDKDKVKVALIGYPNVGKSTI 119
           AE++ +  E     VI++SAR R  T  LR  +K +A   D       +IG+P  GKS++
Sbjct: 62  AEKWARIIEGMGFDVIYVSARHRLSTRRLRGFIKHLA---DVKPFSAGVIGFPKTGKSSV 118

Query: 120 INVLKGKHAVGTAPI---PGYTKGKHLIRLTKRLWLLDTPGVVPID-DFDELVIKGGFPA 175
           IN L+G+    T+PI   PGYTKG  L+++    +++DTPGV+P++  + E +I+G  P 
Sbjct: 119 INALRGRKGAPTSPIPGSPGYTKGLQLLKIEPGFYMVDTPGVIPVEGGWPESIIRGRSPE 178

Query: 176 DKIEEPVKPALKLIRRILETRKEALTEKFDIREFRDEEDILRKIGERRG-IIREGGEVDI 234
           D + +PV PA  LI +IL   + A    + I   +D  +I+ ++  +RG   +   E  I
Sbjct: 179 D-LPDPVPPAAALIEKILRYNRRAFQAAYGITA-QDPYEIMERLAVKRGWFYKTTKEPLI 236

Query: 235 EETARWFLREWQTGRFTLFSNDEE 258
           EE AR  +R++   +   +   EE
Sbjct: 237 EEAARTIIRDYHKAKIPFYVPPEE 260


>gb|AAF30346.1|AC019018_24 (AC019018) putative GTP-binding protein; 106556-109264 [Arabidopsis
           thaliana]
           Length = 576
           
 Score =  160 bits (400), Expect = 3e-38
 Identities = 93/261 (35%), Positives = 146/261 (55%), Gaps = 12/261 (4%)

Query: 2   KQKKAWRIVKEVIGEADIVVEVVDARDPIGTRNRKLERMVIE--SGKKLLIVMNKADLVP 59
           + K+ W  + +VI  +D++V+V+DARDP GTR   LE+ + E    K +++++NK DLVP
Sbjct: 201 QSKRIWGELYKVIDSSDVIVQVIDARDPQGTRCHHLEKTLKEHHKHKHMILLLNKCDLVP 260

Query: 60  ----KEWAEEYKKRSEIPVIFISARERKGTGILRKELKKMAKT-IDKDKVKVALIGYPNV 114
               K W     K         S  +  G G L   L++ A+   DK  + V  +GYPNV
Sbjct: 261 AWATKGWLRVLSKEYPTLAFHASVNKSFGKGSLLSVLRQFARLKSDKQAISVGFVGYPNV 320

Query: 115 GKSTIINVLKGKHAVGTAPIPGYTKGKHLIRLTKRLWLLDTPGVV--PIDDFDELVIKGG 172
           GKS++IN L+ K+    APIPG TK    I LTKR++L+D PGVV    D   ++V+KG 
Sbjct: 321 GKSSVINTLRTKNVCKVAPIPGETKVWQYITLTKRIFLIDCPGVVYQSRDTETDIVLKGV 380

Query: 173 FPADKIEEPVKPALKLIRRILETRKEALTEKFDIREFRDEEDILRKIGERRGIIREGGEV 232
                +E+  +   +++RR+   +KE L   + I+++ D+ D L ++ +  G + +GGE 
Sbjct: 381 VRVTNLEDASEHIGEVLRRV---KKEHLQRAYKIKDWEDDHDFLLQLCKSSGKLLKGGEP 437

Query: 233 DIEETARWFLREWQTGRFTLF 253
           D+   A+  L +WQ GR   F
Sbjct: 438 DLMTGAKMILHDWQRGRIPFF 458


>gi|7019419 nucleolar GTPase [Homo sapiens] >gi|3334276|sp|Q13823|NGP1_HUMAN
           AUTOANTIGEN NGP-1 >gi|179285|gb|AAC37588.1| (L05425)
           nucleolar GTPase [Homo sapiens]
           Length = 731
           
 Score =  151 bits (378), Expect = 1e-35
 Identities = 91/261 (34%), Positives = 142/261 (53%), Gaps = 12/261 (4%)

Query: 2   KQKKAWRIVKEVIGEADIVVEVVDARDPIGTRNRKLERMVIESG--KKLLIVMNKADLVP 59
           + K+ W  + +VI  +D+VV+V+DARDP+GTR+  +E  + +    K L+ V+NK DLVP
Sbjct: 202 QSKRIWGELYKVIDSSDVVVQVLDARDPMGTRSPHIETYLKKEKPWKHLIFVLNKCDLVP 261

Query: 60  ----KEWAEEYKKRSEIPVIFISARERKGTGILRKELKKMAKT-IDKDKVKVALIGYPNV 114
               K W     +         S     G G   + L++  K   DK ++ V  IGYPNV
Sbjct: 262 TWATKRWVAVLSQDYPTLAFHASLTNPFGKGAFIQLLRQFGKLHTDKKQISVGFIGYPNV 321

Query: 115 GKSTIINVLKGKHAVGTAPIPGYTKGKHLIRLTKRLWLLDTPGVV-PIDDFD-ELVIKGG 172
           GKS++IN L+ K     API G TK    I L +R++L+D PGVV P +D + ++V+KG 
Sbjct: 322 GKSSVINTLRSKKVCNVAPIAGETKVWQYITLMRRIFLIDCPGVVYPSEDSETDIVLKGV 381

Query: 173 FPADKIEEPVKPALKLIRRILETRKEALTEKFDIREFRDEEDILRKIGERRGIIREGGEV 232
              +KI+ P      ++ R    + E +++ + I  + + ED L K+  R G + +GGE 
Sbjct: 382 VQVEKIKSPEDHIGAVLER---AKPEYISKTYKIDSWENAEDFLEKLAFRTGKLLKGGEP 438

Query: 233 DIEETARWFLREWQTGRFTLF 253
           D++   +  L +WQ GR   F
Sbjct: 439 DLQTVGKMVLNDWQRGRIPFF 459


>gi|11423270 nucleolar GTPase [Homo sapiens]
           Length = 633
           
 Score =  151 bits (378), Expect = 1e-35
 Identities = 91/261 (34%), Positives = 142/261 (53%), Gaps = 12/261 (4%)

Query: 2   KQKKAWRIVKEVIGEADIVVEVVDARDPIGTRNRKLERMVIESG--KKLLIVMNKADLVP 59
           + K+ W  + +VI  +D+VV+V+DARDP+GTR+  +E  + +    K L+ V+NK DLVP
Sbjct: 104 QSKRIWGELYKVIDSSDVVVQVLDARDPMGTRSPHIETYLKKEKPWKHLIFVLNKCDLVP 163

Query: 60  ----KEWAEEYKKRSEIPVIFISARERKGTGILRKELKKMAKT-IDKDKVKVALIGYPNV 114
               K W     +         S     G G   + L++  K   DK ++ V  IGYPNV
Sbjct: 164 TWATKRWVAVLSQDYPTLAFHASLTNPFGKGAFIQLLRQFGKLHTDKKQISVGFIGYPNV 223

Query: 115 GKSTIINVLKGKHAVGTAPIPGYTKGKHLIRLTKRLWLLDTPGVV-PIDDFD-ELVIKGG 172
           GKS++IN L+ K     API G TK    I L +R++L+D PGVV P +D + ++V+KG 
Sbjct: 224 GKSSVINTLRSKKVCNVAPIAGETKVWQYITLMRRIFLIDCPGVVYPSEDSETDIVLKGV 283

Query: 173 FPADKIEEPVKPALKLIRRILETRKEALTEKFDIREFRDEEDILRKIGERRGIIREGGEV 232
              +KI+ P      ++ R    + E +++ + I  + + ED L K+  R G + +GGE 
Sbjct: 284 VQVEKIKSPEDHIGAVLER---AKPEYISKTYKIDSWENAEDFLEKLAFRTGKLLKGGEP 340

Query: 233 DIEETARWFLREWQTGRFTLF 253
           D++   +  L +WQ GR   F
Sbjct: 341 DLQTVGKMVLNDWQRGRIPFF 361


>pir||T24970 hypothetical protein T19A6.2a - Caenorhabditis elegans
           >gi|3879894|emb|CAA16512.1| (AL021571) predicted using
           Genefinder~contains similarity to Pfam domain: PF01926
           (GTPase of unknown function), Score=317.5,
           E-value=5.2e-92, N=1~cDNA EST yk216b4.5 comes from this
           gene~cDNA EST yk282e12.5 comes from this gene~cDNA EST
           yk292e12.5 comes>
           Length = 698
           
 Score =  150 bits (374), Expect = 3e-35
 Identities = 91/261 (34%), Positives = 146/261 (55%), Gaps = 12/261 (4%)

Query: 2   KQKKAWRIVKEVIGEADIVVEVVDARDPIGTRNRKLERMVIESG--KKLLIVMNKADLVP 59
           +  + W  + +VI  +D+VV+VVDARDP+GTR R +E  + +    K L+ V+NK DLVP
Sbjct: 217 QSNRVWGELYKVIDSSDVVVQVVDARDPMGTRCRHVEEFLRKEKPHKHLVTVINKVDLVP 276

Query: 60  ----KEWAEEYKKRSEIPVIFISARERKGTGILRKELKKMAKTI-DKDKVKVALIGYPNV 114
               ++W  E  K         S     G G +   L++ AK   D+ ++ V  IGYPNV
Sbjct: 277 TWVTRKWIGELSKEMPTIAFHASINNSFGKGAVINLLRQFAKLHPDRPQISVGFIGYPNV 336

Query: 115 GKSTIINVLKGKHAVGTAPIPGYTKGKHLIRLTKRLWLLDTPGVV-PIDDFD-ELVIKGG 172
           GKS+++N L+ K    TAPI G TK    + L +R++L+D+PGVV P  D + ++++KG 
Sbjct: 337 GKSSLVNTLRKKKVCKTAPIAGETKVWQYVMLMRRIYLIDSPGVVYPQGDSETQIILKGV 396

Query: 173 FPADKIEEPVKPALKLIRRILETRKEALTEKFDIREFRDEEDILRKIGERRGIIREGGEV 232
              + +++P      ++ R    + E L  ++ I EF D +D L KI  ++G + +GG+ 
Sbjct: 397 VRVENVKDPENHVQGVLDR---CKPEHLRRQYGIPEFTDVDDFLTKIAIKQGRLLKGGDP 453

Query: 233 DIEETARWFLREWQTGRFTLF 253
           DI   ++  L E+Q G+   F
Sbjct: 454 DIVAVSKVVLNEFQRGKLPYF 474


>pir||T24972 hypothetical protein T19A6.2b - Caenorhabditis elegans
           >gi|3879896|emb|CAA16514.1| (AL021571) contains
           similarity to Pfam domain: PF01926 (GTPase of unknown
           function), Score=317.5, E-value=5.2e-92, N=1~cDNA EST
           yk16b11.3 comes from this gene~cDNA EST yk3g7.3 comes
           from this gene~cDNA EST yk3g7.5 comes from this
           gene~cDNA EST yk146h4.>
           Length = 639
           
 Score =  150 bits (374), Expect = 3e-35
 Identities = 91/261 (34%), Positives = 146/261 (55%), Gaps = 12/261 (4%)

Query: 2   KQKKAWRIVKEVIGEADIVVEVVDARDPIGTRNRKLERMVIESG--KKLLIVMNKADLVP 59
           +  + W  + +VI  +D+VV+VVDARDP+GTR R +E  + +    K L+ V+NK DLVP
Sbjct: 158 QSNRVWGELYKVIDSSDVVVQVVDARDPMGTRCRHVEEFLRKEKPHKHLVTVINKVDLVP 217

Query: 60  ----KEWAEEYKKRSEIPVIFISARERKGTGILRKELKKMAKTI-DKDKVKVALIGYPNV 114
               ++W  E  K         S     G G +   L++ AK   D+ ++ V  IGYPNV
Sbjct: 218 TWVTRKWIGELSKEMPTIAFHASINNSFGKGAVINLLRQFAKLHPDRPQISVGFIGYPNV 277

Query: 115 GKSTIINVLKGKHAVGTAPIPGYTKGKHLIRLTKRLWLLDTPGVV-PIDDFD-ELVIKGG 172
           GKS+++N L+ K    TAPI G TK    + L +R++L+D+PGVV P  D + ++++KG 
Sbjct: 278 GKSSLVNTLRKKKVCKTAPIAGETKVWQYVMLMRRIYLIDSPGVVYPQGDSETQIILKGV 337

Query: 173 FPADKIEEPVKPALKLIRRILETRKEALTEKFDIREFRDEEDILRKIGERRGIIREGGEV 232
              + +++P      ++ R    + E L  ++ I EF D +D L KI  ++G + +GG+ 
Sbjct: 338 VRVENVKDPENHVQGVLDR---CKPEHLRRQYGIPEFTDVDDFLTKIAIKQGRLLKGGDP 394

Query: 233 DIEETARWFLREWQTGRFTLF 253
           DI   ++  L E+Q G+   F
Sbjct: 395 DIVAVSKVVLNEFQRGKLPYF 415


>pir||T23172 hypothetical protein K01C8.9 - Caenorhabditis elegans
           >gi|3878119|emb|CAA88860.1| (Z49068) contains similarity
           to Pfam domain: PF01926 (GTPase of unknown function),
           Score=367.6, E-value=4.1e-107, N=1~cDNA EST EMBL:M89111
           comes from this gene~cDNA EST yk2f7.3 comes from this
           gene~cDNA EST yk2f7.5 comes from this gene~cDNA EST
           yk63b3.>
           Length = 556
           
 Score =  149 bits (372), Expect = 5e-35
 Identities = 82/279 (29%), Positives = 151/279 (53%), Gaps = 32/279 (11%)

Query: 10  VKEVIGEADIVVEVVDARDPIGTRNRKLERMVIESGKKLLIVMNKADLVPKEWAEEYKK- 68
           V++ +  AD++++V+DARDP+G+R++ +E  V++ GK+L++++NK DLVP+E  +++ + 
Sbjct: 141 VRKTVEIADVIIQVLDARDPLGSRSKSVEDQVLKGGKRLVLLLNKIDLVPRENVQKWLEY 200

Query: 69  -RSEIPVIFI--SARERK--------------------GTGILRKELKKMAKTID-KDKV 104
            R + P I    S +E+K                    G  I+ K L    +  D K  +
Sbjct: 201 LRGQFPTIAFKASTQEQKSNIGRFNSAILNNTETSKCVGADIVMKILANYCRNKDIKTSI 260

Query: 105 KVALIGYPNVGKSTIINVLKGKHAVGTAPIPGYTKGKHLIRLTKRLWLLDTPGVVPIDDF 164
           +V ++G+PNVGKS++IN LK + A     +PG TK    + L K + L+D+PGV+ +   
Sbjct: 261 RVGVVGFPNVGKSSVINSLKRRKACNVGNLPGITKEIQEVELDKNIRLIDSPGVILVSQK 320

Query: 165 D----ELVIKGGFPADKIEEPVKPALKLIRRILETRKEALTEKFDIREFRDEEDILRKIG 220
           D    E+ +K     D + +P+ P   ++RR     KE +   +++ +F   +  L ++ 
Sbjct: 321 DLDPIEVALKNAIRVDNLLDPIAPVHAILRR---CSKETIMLHYNLADFNSVDQFLAQLA 377

Query: 221 ERRGIIREGGEVDIEETARWFLREWQTGRFTLFSNDEEK 259
            R G +R G   D+   A+  L +W TG+   +++  E+
Sbjct: 378 RRIGKLRRGARPDVNAAAKRVLNDWNTGKLRYYTHPPEQ 416


>gb|AAB09043.1| (U69600) testicular antigen [Mus musculus]
           Length = 728
           
 Score =  148 bits (369), Expect = 1e-34
 Identities = 91/262 (34%), Positives = 141/262 (53%), Gaps = 12/262 (4%)

Query: 1   MKQKKAWRIVKEVIGEADIVVEVVDARDPIGTRNRKLERMVIESG--KKLLIVMNKADLV 58
           ++ K+ W  + +VI  +D+VV+V+DARDP+GTR+  +E  + +    K L+ V+NK DLV
Sbjct: 201 VQSKRIWGELYKVIDSSDVVVQVLDARDPMGTRSPHIEAYLKKEKPWKHLIFVLNKCDLV 260

Query: 59  P----KEWAEEYKKRSEIPVIFISARERKGTGILRKELKKMAKT-IDKDKVKVALIGYPN 113
           P    K W     +         S     G G   + L    K   DK ++ V  IGYPN
Sbjct: 261 PTWATKRWVAVLSQDYPTLAFHASLTNPFGKGAFIQLLGSFGKLHTDKKQISVGFIGYPN 320

Query: 114 VGKSTIINVLKGKHAVGTAPIPGYTKGKHLIRLTKRLWLLDTPGVV-PIDDFD-ELVIKG 171
           VGKS++IN L+ K     API G TK    I L +R++L+D PGVV P +D + ++V+KG
Sbjct: 321 VGKSSVINTLRSKKVCNVAPIAGETKVWQYITLMRRIFLIDWPGVVYPSEDSETDIVLKG 380

Query: 172 GFPADKIEEPVKPALKLIRRILETRKEALTEKFDIREFRDEEDILRKIGERRGIIREGGE 231
               +KI+ P      ++ R    + E +++ + I  + + ED L K+  R G + +GGE
Sbjct: 381 VVQVEKIKAPQDHIGAVLER---AKPEYISKTYKIESWENAEDFLEKLALRTGKLLKGGE 437

Query: 232 VDIEETARWFLREWQTGRFTLF 253
            D+   ++  L +WQ GR   F
Sbjct: 438 PDMLTVSKMVLNDWQRGRIPFF 459


>gb|AAF57834.1| (AE003802) CG6501 gene product [Drosophila melanogaster]
           Length = 674
           
 Score =  147 bits (367), Expect = 2e-34
 Identities = 90/281 (32%), Positives = 148/281 (52%), Gaps = 21/281 (7%)

Query: 2   KQKKAWRIVKEVIGEADIVVEVVDARDPIGTRNRKLERMVIESG--KKLLIVMNKADLVP 59
           + K+ W  + +V+  +D++++V+DARDP+GTR++ +E  + +    K L  ++NK DLVP
Sbjct: 207 QSKRIWNELHKVVDASDVLLQVLDARDPMGTRSKYIEEFLRKEKPHKHLFFILNKVDLVP 266

Query: 60  ----KEWAEEYKKRSEIPVIFISARERKGTGILRKELKKMAKT-IDKDKVKVALIGYPNV 114
               + W               S +   G G L    +++ K  +DK ++ V  IGYPNV
Sbjct: 267 VWVTQRWVAILSAEYPTIAFHASLQHPFGKGALINLFRQLGKLHLDKKQISVGFIGYPNV 326

Query: 115 GKSTIINVLKGKHAVGTAPIPGYTKGKHLIRLTKRLWLLDTPGVV-PIDDFD-ELVIKGG 172
           GKS++IN L+ K     API G TK    I L KR++L+D PGVV P  + D E V+KG 
Sbjct: 327 GKSSVINALRSKKVCKVAPIAGETKVWQYITLMKRIFLIDCPGVVYPTAETDTEKVLKGV 386

Query: 173 FPADKIEEPVKPALKLIRRILETRKEALTEKFDIREFRDEEDILRKIGERRGIIREGGEV 232
              + +  P      L++R+   R E +++ + I  +      L ++ ++ G + +GGE 
Sbjct: 387 VRVELVTNPEDYVDSLLKRV---RPEYISKNYKIEHWNTSTHFLEQLAQKTGKLLKGGEP 443

Query: 233 DIEETARWFLREWQTGR---------FTLFSNDEEKKEEYI 264
           D+  TAR  L +WQ G+         F +  + E K+EE +
Sbjct: 444 DVTVTARMVLNDWQRGKLPFYVPPEGFAVPKSQEGKEEEVV 484


>pir||T39037 hypothetical gtp-binding protein associated - fission yeast
           (Schizosaccharomyces pombe) >gi|2388994|emb|CAB11727.1|
           (Z98981) hypothetical gtp-binding protein associated
           [Schizosaccharomyces pombe]
           Length = 537
           
 Score =  143 bits (357), Expect = 3e-33
 Identities = 93/274 (33%), Positives = 145/274 (51%), Gaps = 21/274 (7%)

Query: 2   KQKKAWRIVKEVIGEADIVVEVVDARDPIGTRNRKLERMVIE--SGKKLLIVMNKADLVP 59
           + K+ W  + +VI  +D++++V+DARDP+GTR   +ER +    S K +++V+NK DLVP
Sbjct: 202 QSKRIWNELYKVIDSSDVLIQVLDARDPVGTRCGTVERYLRNEASHKHMILVLNKVDLVP 261

Query: 60  KEWAEEYKK--RSEIPVIFISARERK--GTGILRKELKKMAKT-IDKDKVKVALIGYPNV 114
              A  + K    E P I   A      G G L + L++ A    DK ++ V LIG+PN 
Sbjct: 262 TSVAAAWVKILAKEYPTIAFHASINNSFGKGSLIQILRQFASLHSDKKQISVGLIGFPNA 321

Query: 115 GKSTIINVLKGKHAVGTAPIPGYTKGKHLIRLTKRLWLLDTPGVVPIDDFD---ELVIKG 171
           GKS+IIN L+ K     APIPG TK    + L KR++L+D PG+VP    D   EL++KG
Sbjct: 322 GKSSIINTLRKKKVCNVAPIPGETKVWQYVALMKRIFLIDCPGIVPPSSNDSDAELLLKG 381

Query: 172 GFPADKIEEPVKPALKLIRRILETRKEALTEKFDIREFRDEEDILRKIGERRGIIREGGE 231
               + +  P      ++ R    + + L   ++I  + D  + L K+ ++ G + +GGE
Sbjct: 382 VVRVENVSNPEAYIPTVLSR---CKVKHLERTYEISGWNDSTEFLAKLAKKGGRLLKGGE 438

Query: 232 VDIEETARWFLREWQTGRFTLF--------SNDE 257
            D    A+  L ++  G+   F        SNDE
Sbjct: 439 PDEASVAKMVLNDFMRGKIPWFIGPKGLSSSNDE 472


>gb|AAF27009.1|AC016827_20 (AC016827) putative GTPase [Arabidopsis thaliana]
           Length = 582
           
 Score =  143 bits (356), Expect = 4e-33
 Identities = 94/312 (30%), Positives = 162/312 (51%), Gaps = 36/312 (11%)

Query: 3   QKKAWRIVKEVIGEADIVVEVVDARDPIGTRNRKLERMVIESG--KKLLIVMNKADLVPK 60
           ++  ++ + +VI  +D+++EV+DARDP+GTR   +ERMV+++G  K L++++NK DLVP+
Sbjct: 123 ERAFYKELVKVIELSDVILEVLDARDPLGTRCTDMERMVMQAGPNKHLVLLLNKIDLVPR 182

Query: 61  EWAEEYKK--RSEIPVIFI--SARERK-----------------------GTGILRKELK 93
           E AE++    R E P +    S +E++                       G   L K LK
Sbjct: 183 EAAEKWLMYLREEFPAVAFKCSTQEQRSNLGWKSSKASKPSNMLQTSDCLGADTLIKLLK 242

Query: 94  KMAKTID-KDKVKVALIGYPNVGKSTIINVLKGKHAVGTAPIPGYTKGKHLIRLTKRLWL 152
             +++ + K  + V +IG PNVGKS++IN LK  H V     PG T+    + L K + L
Sbjct: 243 NYSRSHELKKSITVGIIGLPNVGKSSLINSLKRAHVVNVGATPGLTRSLQEVHLDKNVKL 302

Query: 153 LDTPGVVPIDDFD---ELVIKGGFPADKIEEPVKPALKLIRRILETRKEALTEKFDIREF 209
           LD PGVV +        + ++     +K+++PV P  ++++      K+ L   + I  F
Sbjct: 303 LDCPGVVMLKSSGNDASIALRNCKRIEKLDDPVSPVKEILKL---CPKDMLVTLYKIPSF 359

Query: 210 RDEEDILRKIGERRGIIREGGEVDIEETARWFLREWQTGRFTLFSNDEEKKEEYIESFGE 269
              +D L K+   RG +++GG VDI+  AR  L +W  G+   ++   ++ +        
Sbjct: 360 EAVDDFLYKVATVRGKLKKGGLVDIDAAARIVLHDWNEGKIPYYTMPPKRDQGGHAESKI 419

Query: 270 ILEVIKQENLTE 281
           + E+ K  N+ E
Sbjct: 420 VTELAKDFNIDE 431


>gi|6324381 Ynr053cp [Saccharomyces cerevisiae]
           >gi|1730685|sp|P53742|YN8U_YEAST HYPOTHETICAL
           GTP-BINDING PROTEIN IN POP2-HOL1 INTERGENIC REGION
           >gi|2131978|pir||S63384 hypothetical protein YNR053c -
           yeast (Saccharomyces cerevisiae)
           >gi|1302570|emb|CAA96334.1| (Z71668) ORF YNR053c
           [Saccharomyces cerevisiae]
           Length = 486
           
 Score =  135 bits (337), Expect = 7e-31
 Identities = 82/271 (30%), Positives = 142/271 (52%), Gaps = 13/271 (4%)

Query: 2   KQKKAWRIVKEVIGEADIVVEVVDARDPIGTRNRKLERMVIESG--KKLLIVMNKADLVP 59
           + K+ W  + +VI  +D+V+ V+DARDP+GTR + +E  + +    K L+ V+NK DLVP
Sbjct: 207 QSKRIWNELYKVIDSSDVVIHVLDARDPLGTRCKSVEEYMKKETPHKHLIYVLNKCDLVP 266

Query: 60  K----EWAEEYKKRSEIPVIFISARERKGTGILRKELKKMAKT-IDKDKVKVALIGYPNV 114
                 W +   K         S     G G L + L++ ++   D+ ++ V  IGYPN 
Sbjct: 267 TWVAAAWVKHLSKERPTLAFHASITNSFGKGSLIQLLRQFSQLHTDRKQISVGFIGYPNT 326

Query: 115 GKSTIINVLKGKHAVGTAPIPGYTKGKHLIRLTKRLWLLDTPGVVP---IDDFDELVIKG 171
           GKS+IIN L+ K     APIPG TK    I L KR++L+D PG+VP    D  ++++ +G
Sbjct: 327 GKSSIINTLRKKKVCQVAPIPGETKVWQYITLMKRIFLIDCPGIVPPSSKDSEEDILFRG 386

Query: 172 GFPADKIEEPVKPALKLIRRILETRKEALTEKFDIREFRDEEDILRKIGERRGIIREGGE 231
               + +  P +    +++R    + + L   ++I  ++D  + +  +  ++G + +GGE
Sbjct: 387 VVRVEHVTHPEQYIPGVLKR---CQVKHLERTYEISGWKDATEFIEILARKQGRLLKGGE 443

Query: 232 VDIEETARWFLREWQTGRFTLFSNDEEKKEE 262
            D    ++  L ++  G+   F    EK+ E
Sbjct: 444 PDESGVSKQILNDFNRGKIPWFVLPPEKEGE 474


>gi|9506611 hypothetical protein [Homo sapiens] >gi|7022755|dbj|BAA91712.1|
           (AK001475) unnamed protein product [Homo sapiens]
           Length = 582
           
 Score =  122 bits (303), Expect = 7e-27
 Identities = 78/283 (27%), Positives = 145/283 (50%), Gaps = 35/283 (12%)

Query: 3   QKKAWRIVKEVIGEADIVVEVVDARDPIGTRNRKLERMVI--ESGKKLLIVMNKADLVPK 60
           +K  ++  ++V+  +D+++EV+DARDP+G R  ++E  V+  +  KKL++V+NK DLVPK
Sbjct: 121 RKAYYKEFRKVVEYSDVILEVLDARDPLGCRCFQMEEAVLRAQGNKKLVLVLNKIDLVPK 180

Query: 61  EWAEEYKK--RSEIPVIFISARERKGTGILRK---ELKKMAKTIDKDK------------ 103
           E  E++    R+E+P +   A  +     L +    + + ++++ K K            
Sbjct: 181 EVVEKWLDYLRNELPTVAFKASTQHQVKNLNRCSVPVDQASESLLKSKACFGAENLMRVL 240

Query: 104 ------------VKVALIGYPNVGKSTIINVLKGKHAVGTAPIPGYTKGKHLIRLTKRLW 151
                       ++V ++G PNVGKS++IN LK   A     +PG TK    + L K + 
Sbjct: 241 GNYCRLGEVRTHIRVGVVGLPNVGKSSLINSLKRSRACSVGAVPGITKFMQEVYLDKFIR 300

Query: 152 LLDTPGVVPIDDFD-ELVIKGGFPADKIEEPVKPALKLIRRILETRKEALTEKFDIREFR 210
           LLD PG+VP  + +   +++      K+ +PV P   +++R      E ++  + +  F+
Sbjct: 301 LLDAPGIVPGPNSEVGTILRNCVHVQKLADPVTPVETILQR---CNLEEISNYYGVSGFQ 357

Query: 211 DEEDILRKIGERRGIIREGGEVDIEETARWFLREWQTGRFTLF 253
             E  L  +  R G  ++GG    E+ A+  L +W +G+ + +
Sbjct: 358 TTEHFLTAVAHRLGKKKKGGLYSQEQAAKAVLADWVSGKISFY 400


>gb|AAF55384.1| (AE003716) CG3983 gene product [Drosophila melanogaster]
           Length = 581
           
 Score =  119 bits (296), Expect = 4e-26
 Identities = 86/291 (29%), Positives = 141/291 (47%), Gaps = 37/291 (12%)

Query: 4   KKAWRIVKEVIGEADIVVEVVDARDPIGTRNRKLERMV--IESGKKLLIVMNKADLVPKE 61
           K+ ++  ++VI  AD+V+EVVDARDP+GTR  ++ER V      K+L++V+NKADLVP+E
Sbjct: 138 KQYFKEFRKVIENADVVLEVVDARDPLGTRCNEVERAVRGAPGNKRLVLVLNKADLVPRE 197

Query: 62  ----WAEEYKKRSEIPVIFISARERKGTGILRKELKKMA--KTID--------------- 100
               W + Y +RS     F ++ + +   + R++L++M   K +                
Sbjct: 198 NLNNWIK-YFRRSGPVTAFKASTQDQANRLGRRKLREMKTEKAMQGSVCIGAELLMSMLG 256

Query: 101 --------KDKVKVALIGYPNVGKSTIINVLKGKHAVGTAPIPGYTKGKHLIRLTKRLWL 152
                   K  ++V ++G PNVGKS+IIN L    +      PG TK    + L  ++ L
Sbjct: 257 NYCRNKGIKTSIRVGVVGIPNVGKSSIINSLTRGRSCMVGSTPGVTKSMQEVELDSKIKL 316

Query: 153 LDTPGVVPID--DFDELVIKGGFPADKIEEPVKPALKLIRRILETRKEALTEKFDIREFR 210
           +D PG+V     +    V+K       +++P   A  +++R     KE     +DI  + 
Sbjct: 317 IDCPGIVFTSGGENSHAVLKNAQRVGDVKDPFTIAESVLKR---ASKEYFCTMYDITNYD 373

Query: 211 DEEDILRKIGERRGIIREGGEVDIEETARWFLREWQTGRFTLFSNDEEKKE 261
             E+   K   R G   + G  D+   AR  L +W TG+    +   E +E
Sbjct: 374 TFEEFFAKKAARMGKFLKKGVPDVVAAARSVLNDWNTGKIKYCTQPPEVQE 424


>pir||T40020 probable protein transport protein - fission yeast
           (Schizosaccharomyces pombe) >gi|3650391|emb|CAA21100.1|
           (AL031743) putative GTPase protein [Schizosaccharomyces
           pombe]
           Length = 470
           
 Score =  119 bits (295), Expect = 6e-26
 Identities = 88/313 (28%), Positives = 154/313 (49%), Gaps = 42/313 (13%)

Query: 11  KEVIGEADIVVEVVDARDPIGTRNRKLERMVIESG---KKLLIVMNKADLVPKEWAEEYK 67
           K+V+  +D+++ V+DARDP GTR++ +ER V+ S    K+L+ V+NK DLVP E   ++ 
Sbjct: 157 KKVVEASDVILYVLDARDPEGTRSKDVERQVLASSAEEKRLIFVINKIDLVPSEVLNKWV 216

Query: 68  K--RSEIPVIFISARERKGTGILRKELKKMAKTID---------------KDKVKVALIG 110
              R+  P I + +    G   L+ +    + TI                K  + V +IG
Sbjct: 217 TYLRNFFPTIPMRSASGSGNSNLKHQSASASSTISNLLKSLKSYSAKKKLKSSLTVGVIG 276

Query: 111 YPNVGKSTIINVLKGKHAVG-TAPIP-----GYTKGKHLIRLTKRLWLLDTPGVV----- 159
           YPNVGKS++IN L  + A G +AP P     G T     ++L  +L L+D+PG+V     
Sbjct: 277 YPNVGKSSVINALVNRSANGRSAPCPAGNVAGMTTSLREVKLDNKLRLVDSPGIVFPSSD 336

Query: 160 PIDDFDELVIKGGFPADKIEEPVKPALKLIRRI--LETRKEALTEKFDIREFRDEEDI-- 215
             DD   LV+     + K+++PV  A  +++ +  +  + E + +++++    +  DI  
Sbjct: 337 SKDDLYRLVMLNAVSSTKVDDPVAVASYILQFLSRVPGQLERMFQRYELPPLLNTSDIDT 396

Query: 216 ----LRKIGERRGIIREGGEVDIEETARWFLREWQTGRFTLFSNDE---EKKEEYIESFG 268
               L  I  +RG +  GG  ++   A   + +W  GR   ++  E   EK    ++   
Sbjct: 397 ATDFLVNIARKRGRLGRGGIPNLNAAANIVINDWHAGRIEWWAEPEVINEKNSSEVQDTQ 456

Query: 269 EILEVIKQENLTE 281
            + E  K+ +L +
Sbjct: 457 IVTEWAKEFDLND 469


>gi|7657048 putative nucleotide binding protein, estradiol-induced [Homo
           sapiens] >gi|6457340|gb|AAF09482.1|AF191018_1 (AF191018)
           E2IG3 [Homo sapiens]
           Length = 560
           
 Score =  116 bits (289), Expect = 3e-25
 Identities = 79/267 (29%), Positives = 147/267 (54%), Gaps = 37/267 (13%)

Query: 10  VKEVIGEADIVVEVVDARDPIGTRNRKLERMVIESG-KKLLIVMNKADLVPKEWAEEYKK 68
           +K+VI  +D+V+EV+DARDP+G R  ++E  +++SG KKL++++NK+DLVPKE  E +  
Sbjct: 134 LKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKSDLVPKENLESWLN 193

Query: 69  --RSEIP-VIFISARERKGTGILRKELKK------------------------MAKTIDK 101
             + E+P V+F ++ + K  G + K +K                           +T  K
Sbjct: 194 YLKKELPTVVFRASTKPKDKGKITKRVKAKKNAAPFRSEVCFGKEGLWKLLGGFQETCSK 253

Query: 102 DKVKVALIGYPNVGKSTIINVLKGKHAVGTAPIPGYTKGKHLIRLTKRLWLLDTPG--VV 159
             ++V +IG+PNVGKS+IIN LK +         G T+   ++ L K++ ++D+P   V 
Sbjct: 254 -AIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQITIIDSPSFIVS 312

Query: 160 PIDDFDELVIKGGFPAD-KIEEPVKPALKLIRRILETRKEALTEKFDIREFRDEEDILRK 218
           P++    L ++   PA  ++ +P++ A  ++ +  + R+  L  K+ +  +R+  +    
Sbjct: 313 PLNSSSALALRS--PASIEVVKPMEAASAILSQ-ADARQVVL--KYTVPGYRNSLEFFTM 367

Query: 219 IGERRGIIREGGEVDIEETARWFLREW 245
           + +RRG+ ++GG  ++E  A+    EW
Sbjct: 368 LAQRRGMHQKGGIPNVEGAAKLLWSEW 394


>gi|11435204 putative nucleotide binding protein, estradiol-induced [Homo
           sapiens]
           Length = 662
           
 Score =  116 bits (288), Expect = 4e-25
 Identities = 79/267 (29%), Positives = 147/267 (54%), Gaps = 37/267 (13%)

Query: 10  VKEVIGEADIVVEVVDARDPIGTRNRKLERMVIESG-KKLLIVMNKADLVPKEWAEEYKK 68
           +K+VI  +D+V+EV+DARDP+G R  ++E  +++SG KKL++++NK+DLVPKE  E +  
Sbjct: 247 LKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKSDLVPKENLESWLN 306

Query: 69  --RSEIP-VIFISARERKGTGILRKELKK------------------------MAKTIDK 101
             + E+P V+F ++ + K  G + K +K                           +T  K
Sbjct: 307 YLKKELPTVVFRASTKPKDKGKITKRVKAKKNAAPFRSEVCFGKEGLWKLLGGFQETCSK 366

Query: 102 DKVKVALIGYPNVGKSTIINVLKGKHAVGTAPIPGYTKGKHLIRLTKRLWLLDTPG--VV 159
             ++V +IG+PNVGKS+IIN LK +         G T+   ++ L K++ ++D+P   V 
Sbjct: 367 -AIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQITIIDSPSFIVS 425

Query: 160 PIDDFDELVIKGGFPAD-KIEEPVKPALKLIRRILETRKEALTEKFDIREFRDEEDILRK 218
           P++    L ++   PA  ++ +P++ A  ++ +  + R+  L  K+ +  +R+  +    
Sbjct: 426 PLNSSSALALRS--PASIEVVKPMEAASAILSQ-ADARQVVL--KYTVPGYRNSLEFFTV 480

Query: 219 IGERRGIIREGGEVDIEETARWFLREW 245
           + +RRG+ ++GG  ++E  A+    EW
Sbjct: 481 LAQRRGMHQKGGIPNVEGAAKLLWSEW 507


>pir||B70180 conserved hypothetical protein BB0643 - Lyme disease spirochete
           >gi|2688581|gb|AAC67000.1| (AE001166) conserved
           hypothetical protein [Borrelia burgdorferi]
           Length = 279
           
 Score =  114 bits (283), Expect = 1e-24
 Identities = 80/261 (30%), Positives = 149/261 (56%), Gaps = 20/261 (7%)

Query: 4   KKAWRIVKEVIGEADIVVEVVDARDPIGTRNRKLERMVIESGKKLLIVMNKADLVPKEWA 63
           K+A  ++K  + +A+IV+E++DAR P  ++N   E++     K  +I+++K+D+      
Sbjct: 13  KRALDLIKNNLQKANIVLEILDARAPFSSKNPLTEKITKNQAK--IILLHKSDVAQINEI 70

Query: 64  EEYKKRSEI--PVIFISARERKGTGILRKEL----KKMA--KTID--KDKVKVALIGYPN 113
            ++KK  E     + IS   +KG   +RK++    KK+A  K I   K+K+KV +IG PN
Sbjct: 71  IKWKKYFENLGNTVIISNIYKKG---MRKQIIDIIKKLAIVKKIKNYKEKIKVLIIGVPN 127

Query: 114 VGKSTIINVLKGKHAVGTAPIPGYTKGKHLIRLTKRLWLLDTPGVVPIDDFDELVIKGGF 173
           VGKS+IIN+L GK +   A  PGYTK   ++++ + + L D PG++  +  D+ + K   
Sbjct: 128 VGKSSIINLLSGKKSAKVANKPGYTKNIQIVKINEEINLFDMPGILWHNLVDQSIAKKLA 187

Query: 174 PADKIEEPVKP----ALKLIRRILETRKEALTEKFDIREFRDEEDILRKIGERRGIIREG 229
             D I+  +      AL L+  + +  K  L +K++I   ++  DIL+   + R +I + 
Sbjct: 188 ILDMIKNEIVDNTDLALYLLEIMDQNNKNILLKKYEIYH-KNSLDILQNFAKARKLIGKK 246

Query: 230 GEVDIEETARWFLREWQTGRF 250
            E+++E+ ++  ++E++ G+F
Sbjct: 247 NELNLEKASKILIKEFREGKF 267


>gi|6320842 Yer006wp [Saccharomyces cerevisiae] >gi|731436|sp|P40010|YEJ6_YEAST
           HYPOTHETICAL GTP-BINDING PROTEIN IN YND1-PAC2 INTERGENIC
           REGION >gi|1077630|pir||S50464 hypothetical protein
           YER006w - yeast (Saccharomyces cerevisiae)
           >gi|603598|gb|AAB64539.1| (U18778) Yer006wp
           [Saccharomyces cerevisiae]
           Length = 520
           
 Score =  111 bits (276), Expect = 1e-23
 Identities = 86/293 (29%), Positives = 141/293 (47%), Gaps = 49/293 (16%)

Query: 2   KQKKAW-RIVKEVIGEADIVVEVVDARDPIGTRNRKLERMVIES-GKKLLIVMNKADLVP 59
           K +KA+ +I K VI  +D+++ V+DARDP  TR+RK+E  V++S GK+L++++NK DL+P
Sbjct: 160 KSRKAYDKIFKSVIDASDVILYVLDARDPESTRSRKVEEAVLQSQGKRLILILNKVDLIP 219

Query: 60  KEWAEEYKK--RSEIPVIFISARER--KGTGILRK--------ELKKMAKTID-----KD 102
               E++    +S  P I + A      GT   RK         L +  KT       K 
Sbjct: 220 PHVLEQWLNYLKSSFPTIPLRASSGAVNGTSFNRKLSQTTTASALLESLKTYSNNSNLKR 279

Query: 103 KVKVALIGYPNVGKSTIINVLKGKHAVGTAPIP-----GYTKGKHLIRLTKRLWLLDTPG 157
            + V +IGYPNVGKS++IN L  +    +   P     G T     I++  +L +LD+PG
Sbjct: 280 SIVVGVIGYPNVGKSSVINALLARRGGQSKACPVGNEAGVTTSLREIKIDNKLKILDSPG 339

Query: 158 VV---------PIDDFDELVIKGGFPADKIEEPVKPALKLIRRILETRKEALTEKF---- 204
           +           ++   EL +    PA  I +P    L L++R+   + + +TE F    
Sbjct: 340 ICFPSENKKRSKVEHEAELALLNALPAKHIVDPYPAVLMLVKRL--AKSDEMTESFKKLY 397

Query: 205 --------DIREFRDEEDILRKIGERRGIIREGGEVDIEETARWFLREWQTGR 249
                   D   F   +  L  +  +RG + +GG  ++       L +W+ G+
Sbjct: 398 EIPPIPANDADTF--TKHFLIHVARKRGRLGKGGIPNLASAGLSVLNDWRDGK 448


>pir||F69880 conserved hypothetical protein ylqF - Bacillus subtilis
           >gi|2633977|emb|CAB13478.1| (Z99112) similar to
           hypothetical proteins [Bacillus subtilis]
           Length = 282
           
 Score =  109 bits (269), Expect = 6e-23
 Identities = 85/273 (31%), Positives = 139/273 (50%), Gaps = 25/273 (9%)

Query: 5   KAWRIVKEVIGEADIVVEVVDARDPIGTRNRKLERMVIESGKKLLIVMNKAD----LVPK 60
           KA R V E +   DIV E+VDAR P+ +RN  +E ++    K  ++++NKAD     V +
Sbjct: 12  KARREVTEKLKLIDIVYELVDARIPMSSRNPMIEDIL--KNKPRIMLLNKADKADAAVTQ 69

Query: 61  EWAEEYKKRSEIPVIFISARERKGTG----------ILRKELKKM-AKTIDKDKVKVALI 109
           +W E ++ +    +  +S     G G          IL+++  +M AK +    ++  +I
Sbjct: 70  QWKEHFENQG---IRSLSINSVNGQGLNQIVPASKEILQEKFDRMRAKGVKPRAIRALII 126

Query: 110 GYPNVGKSTIINVLKGKHAVGTAPIPGYTKGKHLIRLTKRLWLLDTPGVVPIDDFDELV- 168
           G PNVGKST+IN L  K+   T   PG T  +  +++ K L LLDTPG++     DELV 
Sbjct: 127 GIPNVGKSTLINRLAKKNIAKTGDRPGITTSQQWVKVGKELELLDTPGILWPKFEDELVG 186

Query: 169 ---IKGGFPADKIEEPVKPALKLIRRILETRKEALTEKFDIREF-RDEEDILRKIGERRG 224
                 G   D I      A+  +R + E   E L E++ + E   D  ++   IGE+RG
Sbjct: 187 LRLAVTGAIKDSIINLQDVAVFGLRFLEEHYPERLKERYGLDEIPEDIAELFDAIGEKRG 246

Query: 225 IIREGGEVDIEETARWFLREWQTGRFTLFSNDE 257
            +  GG ++ ++T    +R+ +T +F   S ++
Sbjct: 247 CLMSGGLINYDKTTEVIIRDIRTEKFGRLSFEQ 279


>dbj|BAA75361.1| (AB013365) YlqF [Bacillus halodurans] >gi|10175096|dbj|BAB06195.1|
           (AP001515) unknown conserved protein [Bacillus
           halodurans]
           Length = 284
           
 Score =  108 bits (266), Expect = 1e-22
 Identities = 81/263 (30%), Positives = 136/263 (50%), Gaps = 23/263 (8%)

Query: 5   KAWRIVKEVIGEADIVVEVVDARDPIGTRNRKLERMVIESGKKLLIVMNKADLVP----K 60
           KA R V E +   D+V+E++DAR P+ +RN  ++ +V    K  L+++NK DL      K
Sbjct: 12  KARREVTEKLKLIDVVIELLDARVPLSSRNPMMDEIVAH--KPRLVLLNKDDLADPSKTK 69

Query: 61  EWAEEYKKRSEIPVIFISARERKGTGILRKELKKMAKT-IDKDKVK--------VALIGY 111
           EW   +++     V+ I+A+  +G   +    + +A+  I+K + K          ++G 
Sbjct: 70  EWTRFFEEGGAT-VLPINAQTGQGVSRISPACQTLAQALIEKQRAKGMKPRAIRAMILGI 128

Query: 112 PNVGKSTIINVLKGKHAVGTAPIPGYTKGKHLIRLTKRLWLLDTPGVVPIDDFDE----- 166
           PNVGKST+IN L  K        PG TK +  I++ K L LLDTPG++    FD+     
Sbjct: 129 PNVGKSTLINRLASKRIAKVGDRPGITKQQQWIKVGKELELLDTPGIL-WPKFDDQATGF 187

Query: 167 LVIKGGFPADKIEEPVKPALKLIRRILETRKEALTEKFDIREF-RDEEDILRKIGERRGI 225
            +   G   D++ +    AL ++R + E   + L +++ + E   D   +   IG++RG 
Sbjct: 188 RLAATGAIKDELLDFQDVALFVLRYMREMYPDRLMDRYKLNELPEDGVTLFDAIGKKRGH 247

Query: 226 IREGGEVDIEETARWFLREWQTG 248
           +  GG +D ++TA   LRE + G
Sbjct: 248 LLSGGYIDYDKTAEMILRELRAG 270


>pir||F72336 conserved hypothetical protein - Thermotoga maritima (strain MSB8)
           >gi|4981296|gb|AAD35850.1|AE001746_11 (AE001746)
           conserved hypothetical protein [Thermotoga maritima]
           Length = 262
           
 Score =  105 bits (260), Expect = 7e-22
 Identities = 84/257 (32%), Positives = 125/257 (47%), Gaps = 37/257 (14%)

Query: 4   KKAWRIVKEVIGEADIVVEVVDARDPIGTRNRKLERMVIESGKKLLIVMNKADLVP---- 59
           +KA R +K+++   + VVEV DAR P  T    ++     S K+ +I++NK D+      
Sbjct: 9   EKAKRQIKDLLRLVNTVVEVRDARAPFATSAYGVDF----SRKETIILLNKVDIADEKTT 64

Query: 60  KEWAEEYKKRSEIPVIFISARERKGTGILRKELKKMAKTIDKDKVKVALIGYPNVGKSTI 119
           K+W E +KK+ +  +       RK   +L K+L     + D+   +V ++G PN GKSTI
Sbjct: 65  KKWVEFFKKQGKRVITTHKGEPRK---VLLKKL-----SFDR-LARVLIVGVPNTGKSTI 115

Query: 120 INVLKGKHAVGTAPIPGYTKGKHLIRLTKRLWLLDTPGVVPIDDFDE-----LVIKGGFP 174
           IN LKGK A      PG TKG     L   + +LDTPG++  + F E     L++ G  P
Sbjct: 116 INKLKGKRASSVGAQPGITKGIQWFSLENGVKILDTPGILYKNIFSEDLAAKLLLVGSLP 175

Query: 175 ADKIEEPVKPALKLIRRILETRKEALTEKFDIREFRDE--EDILRKIGERRGIIREGGEV 232
            ++IE+         +RI E   E       I     E  ED  RK    RG++++GG  
Sbjct: 176 VERIED---------QRIFERAFEIFARSIGIESSFSEFFEDFARK----RGLLKKGGVP 222

Query: 233 DIEETARWFLREWQTGR 249
           DIE     F  E   G+
Sbjct: 223 DIERALMLFFTEVAQGK 239


>sp|Q10190|YAWG_SCHPO HYPOTHETICAL GTP-BINDING PROTEIN C3F10.16C IN CHROMOSOME I
           >gi|7492623|pir||T38717 probable GTP-binding protein -
           fission yeast  (Schizosaccharomyces pombe)
           >gi|1182063|emb|CAA93314.1| (Z69369) putative
           GTP-binding protein [Schizosaccharomyces pombe]
           Length = 616
           
 Score =  105 bits (260), Expect = 7e-22
 Identities = 91/301 (30%), Positives = 139/301 (45%), Gaps = 60/301 (19%)

Query: 7   WRIVKEVIGEADIVVEVVDARDPIGTRNRKLERMVIESG--KKLLIVMNKADLVPKE--- 61
           WR +  VI  +D+VV++VDAR+P+  R+  LE+ V E G  KK  +++NKAD++ +E   
Sbjct: 161 WRQLWRVIERSDVVVQIVDARNPLFFRSAHLEQYVKEVGPSKKNFLLVNKADMLTEEQRN 220

Query: 62  -WAEEYKKRSEIPVIFISAR---ERKGTG------------------------------- 86
            W+  Y   + IP +F SAR   E    G                               
Sbjct: 221 YWSS-YFNENNIPFLFFSARMAAEANERGEDLETYESTSSNEIPESLQADENDVHSSRIA 279

Query: 87  ---ILRKELKKMAKTIDKDKVKVA--LIGYPNVGKSTIINVLKGKHAVGTAPIPGYTKGK 141
              +L    +K A T+   K K+   L+GYPNVGKS+ IN L G   V  +  PG TK  
Sbjct: 280 TLKVLEGIFEKFASTLPDGKTKMTFGLVGYPNVGKSSTINALVGSKKVSVSSTPGKTKHF 339

Query: 142 HLIRLTKRLWLLDTPGVVPIDDF----DELVIKGGFPADKIEEPVKPALKLIRRILETRK 197
             I L++++ LLD PG+V    F     +LV+ G  P D++ E   P+  +  RI +   
Sbjct: 340 QTINLSEKVSLLDCPGLV-FPSFATTQADLVLDGVLPIDQLREYTGPSALMAERIPKEVL 398

Query: 198 EAL-TEKFDIREFRD-------EEDILRKIGERRGIIR-EGGEVDIEETARWFLREWQTG 248
           E L T +  I+   +        +++L      RG +R   G  D    AR  L+++  G
Sbjct: 399 ETLYTIRIRIKPIEEGGTGVPSAQEVLFPFARSRGFMRAHHGTPDDSRAARILLKDYVNG 458

Query: 249 R 249
           +
Sbjct: 459 K 459


>pir||E81941 hypothetical protein NMA0950 [imported] - Neisseria meningitidis
           (group A strain Z2491) >gi|7379653|emb|CAB84220.1|
           (AL162754) hypothetical protein NMA0950 [Neisseria
           meningitidis Z2491]
           Length = 313
           
 Score =  104 bits (257), Expect = 2e-21
 Identities = 81/266 (30%), Positives = 126/266 (46%), Gaps = 21/266 (7%)

Query: 5   KAWRIVKEVIGEADIVVEVVDARDPIGTRNRKLERMVIESGKKLLIVMNKADLVPKE--- 61
           KA + + E     D+V+E++DAR P  + N  L ++    GK  L ++NK DL   E   
Sbjct: 12  KAKKAIAERAKSVDMVIEMLDARMPASSENPLLAQL--SKGKPKLKILNKQDLADPERTK 69

Query: 62  -WAEEYKKRSEIPVIFISARERKGTGILRKELKKMA---KTIDKDKVKVALIGYPNVGKS 117
            W E Y  R +   I + + E    G + +  + M    + IDK  ++V + G PNVGKS
Sbjct: 70  IWLEHYNSRPDTCAIALDSSETGAHGKITQACRAMIPHRQGIDKP-LRVLICGIPNVGKS 128

Query: 118 TIINVLKGKHAVGTAPIPGYTKGKHLIRLTKRLWLLDTPGV----VPIDDFDELVIKGGF 173
           T+IN + GK +  T   PG TK +  + L    WL DTPG+    + +++    +  GG 
Sbjct: 129 TLINGMIGKKSAKTGNEPGITKAEQRLFLADDFWLYDTPGMLWPKIIVEESGYNLAAGGS 188

Query: 174 PADKIEEPVKPALKLI----RRILETRKEALTEKFDIREFRDEEDILRKIGERRGIIREG 229
                 +  + AL+L+    R  L   +E      D     DE   L  I ++RG +  G
Sbjct: 189 VGRNALDEEEVALELLDYLRRHYLPMLQERYQADKDPSSHWDENVWLEWIAKKRGAVLSG 248

Query: 230 GEVDIEETARWFL---REWQTGRFTL 252
           G ++ ++ A   L   RE + GR TL
Sbjct: 249 GRINYQKAAENILTDFREGKIGRITL 274


>pir||C81165 conserved hypothetical protein NMB0739 [imported] - Neisseria
           meningitidis (group B strain MD58)
           >gi|7225967|gb|AAF41152.1| (AE002428) conserved
           hypothetical protein [Neisseria meningitidis MC58]
           Length = 505
           
 Score =  104 bits (256), Expect = 2e-21
 Identities = 81/266 (30%), Positives = 126/266 (46%), Gaps = 21/266 (7%)

Query: 5   KAWRIVKEVIGEADIVVEVVDARDPIGTRNRKLERMVIESGKKLLIVMNKADLVPKE--- 61
           KA + + E     D+V+E++DAR P  + N  L ++    GK  L ++NK DL   E   
Sbjct: 12  KAKKAIAERAKSVDMVIEMLDARMPASSENPLLAQL--SKGKPKLKILNKQDLADPERTK 69

Query: 62  -WAEEYKKRSEIPVIFISARERKGTGILRKELKKMA---KTIDKDKVKVALIGYPNVGKS 117
            W E Y  R +   I + + E    G + +  + M    + IDK  ++V + G PNVGKS
Sbjct: 70  IWLEHYNSRPDTCAIALDSSETGAHGKITQACRAMIPHRQGIDKP-LRVLICGIPNVGKS 128

Query: 118 TIINVLKGKHAVGTAPIPGYTKGKHLIRLTKRLWLLDTPGV----VPIDDFDELVIKGGF 173
           T+IN + GK +  T   PG TK +  + L    WL DTPG+    + +++    +  GG 
Sbjct: 129 TLINGMIGKKSAKTGNEPGITKAEQRLFLADDFWLYDTPGMLWPKIIVEEGGYNLAAGGA 188

Query: 174 PADKIEEPVKPALKLI----RRILETRKEALTEKFDIREFRDEEDILRKIGERRGIIREG 229
                 +  + AL+L+    R  L   +E      D     DE   L  I ++RG +  G
Sbjct: 189 VGRNALDEEEVALELLDYLRRHYLPMLQERYQADKDPSSHWDENVWLEWIAKKRGAVLSG 248

Query: 230 GEVDIEETARWFL---REWQTGRFTL 252
           G ++ ++ A   L   RE + GR TL
Sbjct: 249 GRINYQKAAENILTDFREGKIGRITL 274


>pir||E82449 conserved hypothetical protein VCA0528 [imported] - Vibrio cholerae
           (group O1 strain N16961) >gi|9657934|gb|AAF96431.1|
           (AE004383) conserved hypothetical protein [Vibrio
           cholerae]
           Length = 314
           
 Score = 96.0 bits (235), Expect = 6e-19
 Identities = 69/257 (26%), Positives = 122/257 (46%), Gaps = 17/257 (6%)

Query: 5   KAWRIVKEVIGEADIVVEVVDARDPIGTRNRKLERMVIESGKKLLIVMNKADLVPKE--- 61
           KA + ++E I + D+++EV+DAR P  + N  +    I   K  + V+NK DL   E   
Sbjct: 15  KARKEIEEAIPQVDVIIEVLDARIPFSSENPLISH--IRGEKPCVKVLNKRDLADPELTE 72

Query: 62  -WAEEYKKRSEIPVIFISARERKGTGILRKELKKMAKTIDK--DKVKVALIGYPNVGKST 118
            W    ++   +  + I+    +    + +  +K+A   ++    ++  ++G PNVGKST
Sbjct: 73  LWIAHLEQEKGVKAMAITTSNPQEVHKILELCRKLAPQREEIGKNIRTMIMGIPNVGKST 132

Query: 119 IINVLKGKHAVGTAPIPGYTKGKHLIRLTKRLWLLDTPGVV------PIDDFDELVIKGG 172
           IIN L G+    T   P  T+ +  I L   + L DTPG++      P   F   +   G
Sbjct: 133 IINTLAGRAIAQTGNQPAVTRRQQRINLQNGIVLSDTPGILWPKVENPHSGF--RLAATG 190

Query: 173 FPADKIEEPVKPALKLIRRILETRKEALTEKFDIREFRDEE-DILRKIGERRGIIREGGE 231
              D   E  + A   +  + +   E L E++ I E  + + +++ +IG +RG +R G  
Sbjct: 191 AVKDTAMEYDEVAFYTVEYLAKHYPERLKERYQIDELPETDVELMEEIGRKRGALRAGAR 250

Query: 232 VDIEETARWFLREWQTG 248
           VD+ + +   L E + G
Sbjct: 251 VDLHKASEILLHELRQG 267


>gi|6321339 Ygl099wp [Saccharomyces cerevisiae]
           >gi|1723894|sp|P53145|YGJ9_YEAST HYPOTHETICAL
           GTP-BINDING PROTEIN IN SEH1-PRP20 INTERGENIC REGION
           >gi|2131584|pir||S64106 hypothetical protein YGL099w -
           yeast (Saccharomyces cerevisiae)
           >gi|1322637|emb|CAA96805.1| (Z72621) ORF YGL099w
           [Saccharomyces cerevisiae]
           Length = 640
           
 Score = 92.4 bits (226), Expect = 7e-18
 Identities = 86/313 (27%), Positives = 143/313 (45%), Gaps = 71/313 (22%)

Query: 5   KAWRIVKEVIGEADIVVEVVDARDPIGTRNRKLERMVIESG--KKLLIVMNKADLVPKE- 61
           + W+ +  V+  +D+VV++VDAR+P+  R+  LER V ES   K  L+++NKADL+ K+ 
Sbjct: 186 EVWKQLWRVVERSDLVVQIVDARNPLLFRSVDLERYVKESDDRKANLLLVNKADLLTKKQ 245

Query: 62  ---WAEEYKKRSEIPVIFISA------------------------RERKGTGILRKELKK 94
              WA+ +  ++ I   F SA                         +++G     K ++K
Sbjct: 246 RIAWAKYFISKN-ISFTFYSALRANQLLEKQKEMGEDYREQDFEEADKEGFDADEKVMEK 304

Query: 95  MAKTIDKDK------------------------VKVALIGYPNVGKSTIINVLKGKHAVG 130
           + K +  D+                        + + L+GYPNVGKS+ IN L G   V 
Sbjct: 305 V-KILSIDQLEELFLSKAPNEPLLPPLPGQPPLINIGLVGYPNVGKSSTINSLVGAKKVS 363

Query: 131 TAPIPGYTKGKHLIRLTKRLWLLDTPGVVPIDDF----DELVIKGGFPADKIEEPVKPAL 186
            +  PG TK    I+L+  + L D PG+V   +F     ELV  G  P D++ + + PA 
Sbjct: 364 VSSTPGKTKHFQTIKLSDSVMLCDCPGLV-FPNFAYNKGELVCNGVLPIDQLRDYIGPAG 422

Query: 187 KLIRRILETRKEALTEKFDIREFRDE---------EDILRKIGERRGIIREG-GEVDIEE 236
            +  RI +   EA+       + RDE         +++L      RG + +G G  D   
Sbjct: 423 LVAERIPKYYIEAIYGIHIQTKSRDEGGNGDIPTAQELLVAYARARGYMTQGYGSADEPR 482

Query: 237 TARWFLREWQTGR 249
            +R+ L+++  G+
Sbjct: 483 ASRYILKDYVNGK 495


>gb|AAD15335.1| (AC004044) hypothetical protein [Arabidopsis thaliana]
           >gi|7269764|emb|CAB77764.1| (AL161495) hypothetical
           protein [Arabidopsis thaliana]
           Length = 375
           
 Score = 90.9 bits (222), Expect = 2e-17
 Identities = 77/266 (28%), Positives = 132/266 (48%), Gaps = 28/266 (10%)

Query: 5   KAWRIVKEVIGEADIVVEVVDARDPIGTRNRKLERMVIESGKKLLIVMNKADLVPKE--- 61
           K  + ++E +   D+V+EV DAR P+ T + K++  +    +K ++V+N+ D++  +   
Sbjct: 108 KTEKELREQLKLMDVVIEVRDARIPLSTTHPKMDAWL--GNRKRILVLNREDMISNDDRN 165

Query: 62  -WAEEYKKRSEIPVIFISARERKGT---GILRKEL------KKMAKTIDKDKVKVALIGY 111
            WA  + K+  I VIF + +   G    G L K L      K+  K +    V+  +IGY
Sbjct: 166 DWARYFAKQG-IKVIFTNGKLGMGAMKLGRLAKSLAGDVNGKRREKGLLPRSVRAGIIGY 224

Query: 112 PNVGKSTIINVLKGKHAVGTAPIPGYTKGKHLIRLTKRLWLLDTPGVVPIDDFDELVIKG 171
           PNVGKS++IN L  +     AP PG T+    ++L K L LLD+PG++P+   D+     
Sbjct: 225 PNVGKSSLINRLLKRKICAAAPRPGVTREMKWVKLGKDLDLLDSPGMLPMRIDDQAAAIK 284

Query: 172 GFPADKIEEPVKP-------ALKLIRRILETRKEALTEKFDIREFRDEEDILRKIGERRG 224
               D I E            ++++ RI E   +AL  ++ I+    E +  +K  +  G
Sbjct: 285 LAICDDIGEKAYDFTDVAGILVQMLARIPEVGAKALYNRYKIQL---EGNCGKKFVKTLG 341

Query: 225 IIREGGEVDIEETARWFLREWQTGRF 250
           +   GG  D  + A   L +++ G+F
Sbjct: 342 LNLFGG--DSHQAAFRILTDFRKGKF 365


>pir||S75087 hypothetical protein slr0267 - Synechocystis sp. (strain PCC 6803)
           >gi|1653032|dbj|BAA17949.1| (D90910) hypothetical
           protein [Synechocystis sp.]
           Length = 279
           
 Score = 89.3 bits (218), Expect = 6e-17
 Identities = 52/169 (30%), Positives = 97/169 (56%), Gaps = 14/169 (8%)

Query: 5   KAWRIVKEVIGEADIVVEVVDARDPIGTRNRKLERMVIESGKKLLIVMNKADLVPKEWAE 64
           KA R ++E + + D+V+EV+DAR P+ +++  +   V E  K  LI++N+ D++  E  E
Sbjct: 13  KAERQLREQLNKVDVVLEVIDARIPLASQHPDVPLWVGEKPK--LIILNRVDMITPELQE 70

Query: 65  EYK---KRSEIPVIFISARERKGTGILRKELKKMAKTIDKDK---------VKVALIGYP 112
           ++    ++    V + +A++  G   + K  ++  K +++ +         V+  ++G+P
Sbjct: 71  QWLTWFRQQNQTVYYANAKQGTGVKAISKAAQQAGKAVNERRQRRGMQPRPVRAVVMGFP 130

Query: 113 NVGKSTIINVLKGKHAVGTAPIPGYTKGKHLIRLTKRLWLLDTPGVVPI 161
           NVGKS +IN L G+  V +A   G T+    IR++  L LLD+PGV+P+
Sbjct: 131 NVGKSALINRLLGRKVVESARRAGVTRQLRWIRISDSLELLDSPGVIPL 179


>dbj|BAA92116.1| (AK002163) unnamed protein product [Homo sapiens]
           Length = 642
           
 Score = 71.8 bits (173), Expect = 1e-11
 Identities = 54/174 (31%), Positives = 84/174 (48%), Gaps = 14/174 (8%)

Query: 88  LRKELKKMAKTIDKDKVKVALIGYPNVGKSTIINVLKGKHAVGTAPIPGYTKGKHLIRLT 147
           L KEL    K  D  ++ V L+GYPNVGKS+ IN + G   V  +  PG+TK    + + 
Sbjct: 372 LFKELHTGRKVKD-GQLTVGLVGYPNVGKSSTINTIMGNKKVSVSATPGHTKHFQTLYVE 430

Query: 148 KRLWLLDTPGVVP---IDDFDELVIKGGFPADKIEEPVKPALKLIRRILETRKEALTEKF 204
             L L D PG+V    +    E+   G  P D++ + V P   + + I     EA T   
Sbjct: 431 PGLCLCDCPGLVMPSFVSTKAEMTCSGILPIDQMRDHVPPVSLVCQNIPRHVLEA-TYGI 489

Query: 205 DIREFRDEED---------ILRKIGERRGIIREGGEVDIEETARWFLREWQTGR 249
           +I   R++ED         +L   G  RG +   G+ D   +AR+ L+++ +G+
Sbjct: 490 NIITPREDEDPHRPPTSEELLTAYGYMRGFMTAHGQPDQPRSARYILKDYVSGK 543


>sp|O67749|ENGA_AQUAE PROBABLE GTP-BINDING PROTEIN ENGA >gi|7450585|pir||A70465 probable
           GTP binding protein - Aquifex aeolicus
           >gi|2984183|gb|AAC07715.1| (AE000763) GTP binding
           protein Era [Aquifex aeolicus]
           Length = 433
           
 Score = 71.4 bits (172), Expect = 1e-11
 Identities = 53/161 (32%), Positives = 89/161 (54%), Gaps = 12/161 (7%)

Query: 8   RIVKEVIGEADIVVEVVDARDPIGTRNRKLERMVIESGKKLLIVMNKADLVPKEW--AEE 65
           ++V++ I +AD+++ VVD ++ +   ++++ + +     K+L+V+NK D + +E   AE 
Sbjct: 74  KVVEQEIPKADVILFVVDGKEGLNPLDQEIAKYLYPYADKVLLVVNKIDNLRQEKNVAEF 133

Query: 66  YKKRSEIPVIFISARERKGTGILRKELKKMAK-----TIDKDKVKVALIGYPNVGKSTII 120
           Y    E  +  ISA+  KG G L  E+ K  K     T+++  +KVA IG PNVGKS+++
Sbjct: 134 YTLGFE-KIFPISAQHGKGVGELLDEVVKYLKEEKVETVEEG-IKVAFIGRPNVGKSSLV 191

Query: 121 NVLKGKHAVGTAPIPGYTKGKHLIRL---TKRLWLLDTPGV 158
           N +     V  +PI G T+    I      K   L+DT GV
Sbjct: 192 NAILKDERVIVSPIAGTTRDAIEIPFRWKDKNFILIDTAGV 232


>pir||S40612 myosin-related protein - slime mold (Physarum polycephalum)
           >gi|511053|emb|CAA79924.1| (Z21878) myosin-related
           protein [Physarum polycephalum]
           Length = 341
           
 Score = 69.5 bits (167), Expect = 6e-11
 Identities = 49/141 (34%), Positives = 74/141 (51%), Gaps = 32/141 (22%)

Query: 11  KEVIGEADIVVEVVDARDPIGTRNRKLERMVIES--GKKLLIVMNKADLVPKEWAEE--- 65
           K+V+  AD+++EV+DARDP+G R   +E  +      KK+++++NK DLVPK+  E+   
Sbjct: 159 KKVVESADVIIEVLDARDPMGCRCPDVENTIATKYPNKKIILLLNKIDLVPKQNVEKWMA 218

Query: 66  YKKRSEIPVIFISARERKGTGILRKE-------------------------LKKMAKT-I 99
           Y + S   V F S+ ++KG  I  KE                         LK  A+T  
Sbjct: 219 YLRNSYPTVAFKSSTQKKGK-ISHKESKFTKATNSDLMGSESLGGDALLQLLKHYARTGT 277

Query: 100 DKDKVKVALIGYPNVGKSTII 120
            +    V LIG+PNVGKS++I
Sbjct: 278 IRTSTTVGLIGFPNVGKSSVI 298


>dbj|BAB14161.1| (AK022657) unnamed protein product [Homo sapiens]
           Length = 148
           
 Score = 69.5 bits (167), Expect = 6e-11
 Identities = 42/126 (33%), Positives = 64/126 (50%), Gaps = 10/126 (7%)

Query: 43  ESGKKLLIVMNKADLVPKE---WAEEYKKRSEIPVIFISARERKGTGILRKELKKMAKTI 99
           E  KKL++V+ K DL PKE   W +    R+E+P +   AR +       + L ++    
Sbjct: 9   EGNKKLVLVLKKIDLDPKEVVKWLDYL--RNELPTVAFKARTQHQVSFGAENLMRVLGNY 66

Query: 100 D-----KDKVKVALIGYPNVGKSTIINVLKGKHAVGTAPIPGYTKGKHLIRLTKRLWLLD 154
                 +  + + ++G PN+GKS++I  LK  HA     IPG TK    + L K + LLD
Sbjct: 67  CCLGEMRTHIHMDIVGLPNIGKSSLIKSLKHSHACSVGAIPGVTKFMQEVYLDKFIRLLD 126

Query: 155 TPGVVP 160
            P +VP
Sbjct: 127 APAIVP 132


>emb|CAB38462.1| (AL035632) /prediction=(method:""genefinder"", version:""084"",
           score:""113.36"")~/prediction=(method:""genscan"",
           version:""1.0"",
           score:""309.87"")~/match=(desc:""HYPOTHETICAL
           GTP-BINDING PROTEIN IN SEH1-PRP20 INTERGENIC REGION"",
           species:""Saccharom> >gi|7290165|gb|AAF45628.1|
           (AE003421) EG:BACN32G11.5 gene product [Drosophila
           melanogaster]
           Length = 606
           
 Score = 69.1 bits (166), Expect = 8e-11
 Identities = 49/158 (31%), Positives = 79/158 (49%), Gaps = 13/158 (8%)

Query: 104 VKVALIGYPNVGKSTIINVLKGKHAVGTAPIPGYTKGKHLIRLTKRLWLLDTPGVVP--- 160
           V V ++GYPNVGKS+ IN L     V  +  PG TK    + L K + L D PG+V    
Sbjct: 338 VTVGMVGYPNVGKSSTINSLMTVKKVSVSATPGKTKRFQTLFLDKDILLCDCPGLVMPSF 397

Query: 161 IDDFDELVIKGGFPADKIEEPVKPALKLI-----RRILETRKEALTEK----FDIREFRD 211
           +    ++++ G  P D++ + V PA+ L+     R +LE +   +  K     D+     
Sbjct: 398 VLTKADMLLNGILPIDQMRDHV-PAVNLLCERIPRHVLEDKYGIVIAKPLEGEDMERPPH 456

Query: 212 EEDILRKIGERRGIIREGGEVDIEETARWFLREWQTGR 249
            E++L   G  RG +   G+ D   +AR+ L+++  GR
Sbjct: 457 SEELLLAYGYNRGFMTSNGQPDQARSARYVLKDYVNGR 494


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.319    0.141    0.405 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 137711795
Number of Sequences: 2977
Number of extensions: 6240508
Number of successful extensions: 19989
Number of sequences better than 1.0e-10: 39
Number of HSP's better than  0.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 32
Number of HSP's that attempted gapping in prelim test: 19882
Number of HSP's gapped (non-prelim): 48
length of query: 355
length of database: 189,106,746
effective HSP length: 55
effective length of query: 300
effective length of database: 156,189,961
effective search space: 46856988300
effective search space used: 46856988300
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 165 (68.7 bits)