BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0931 (cysS) DE:cysteinyl-tRNA synthetase (cysS)
(477 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||A75052 cysteinyl-tRNA synthetase (cyss) PAB0931 - Pyrococcu... 983 0.0
sp|O58370|SYC_PYRHO CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LI... 892 0.0
pir||T47278 cysteine--tRNA ligase (EC 6.1.1.16) [validated] - Me... 661 0.0
sp|Q06752|SYC_BACSU CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LI... 480 e-134
sp|O67163|SYC_AQUAE CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LI... 474 e-133
sp|Q9WZH8|SYC_THEMA CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LI... 474 e-132
sp|Q9KGF4|SYC_BACHD CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LI... 469 e-131
sp|Q9YBK6|SYC_AERPE CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LI... 455 e-127
emb|CAB71305.1| (AJ130879) cysteinyl tRNA synthetase [Clostridiu... 453 e-126
gb|AAK42442.1| Cysteinyl-tRNA synthetase (cysS) [Sulfolobus solf... 447 e-124
pir||G83421 cysteinyl-tRNA synthetase PA1795 [imported] - Pseudo... 445 e-124
gi|11498023 cysteinyl-tRNA synthetase (cysS) [Archaeoglobus fulg... 444 e-123
sp|P43816|SYC_HAEIN CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LI... 433 e-120
sp|Q9KQZ9|SYC_VIBCH CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LI... 427 e-118
pir||H82030 cysteine--tRNA ligase (EC 6.1.1.16) NMA0347 [importe... 424 e-117
gb|AAD20662.1| (AC006593) putative cysteinyl-tRNA synthetase [Ar... 424 e-117
sp|P21888|SYC_ECOLI CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LI... 423 e-117
emb|CAA39691.1| (X56234) cysteine-tRNA ligase [Escherichia coli] 421 e-117
pir||B81007 cysteinyl-tRNA synthetase NMB2083 [imported] - Neiss... 418 e-116
emb|CAC12272.1| (AL445066) probable cysteinyl-tRNA synthetase [T... 418 e-116
gb|AAF06821.1|AF065890_2 (AF065890) cysteinyl-tRNA synthetase [T... 416 e-115
sp|P74330|SYC_SYNY3 CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LI... 413 e-114
dbj|BAB08639.1| (AB009048) cysteine-tRNA ligase [Arabidopsis tha... 395 e-109
gb|AAF18751.1|AF164201_1 (AF164201) cysteinyl-tRNA synthetase [M... 385 e-106
pir||A75368 cysteinyl-tRNA synthetase - Deinococcus radiodurans ... 378 e-104
sp|Q9RTT6|SYC_DEIRA CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LI... 378 e-104
sp|Q9PLE0|SYC_CHLMU CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LI... 347 2e-94
emb|CAB77329.1| (AL160331) putative cysteinyl-tRNA synthetase [S... 344 1e-93
sp|Q9ZE62|SYC_RICPR CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LI... 344 2e-93
sp|P57558|SYC_BUCAI CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LI... 343 2e-93
sp|O84787|SYC_CHLTR CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LI... 341 1e-92
pir||F71472 cysteine--tRNA ligase (EC 6.1.1.16) - Chlamydia trac... 341 1e-92
pir||C82737 cysteinyl-tRNA synthetase XF0995 [imported] - Xylell... 337 2e-91
gb|AAG19494.1| (AE005041) cysteinyl-tRNA synthetase; CysS [Halob... 335 9e-91
sp|P41259|SYC_HELPY CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LI... 329 4e-89
sp|Q9ZKW6|SYC_HELPJ CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LI... 329 4e-89
sp|P96862|SYC1_MYCTU CYSTEINYL-TRNA SYNTHETASE 1 (CYSTEINE--TRNA... 327 2e-88
sp|Q9Z6X4|SYC_CHLPN CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LI... 326 2e-88
pir||T47747 cysteine-tRNA ligase - Arabidopsis thaliana >gi|7572... 321 1e-86
gb|AAF18749.1|AF162864_1 (AF162864) cysteinyl-tRNA synthetase [R... 317 2e-85
dbj|BAB13978.1| (AK022180) unnamed protein product [Homo sapiens] 314 2e-84
sp|Q9PPB8|SYC_CAMJE CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LI... 304 1e-81
gb|AAF58291.1| (AE003815) CG8257 gene product [Drosophila melano... 285 9e-76
pir||F53402 cysteine--tRNA ligase (EC 6.1.1.16) - Bacillus stear... 284 1e-75
sp|O83129|SYC_TREPA CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LI... 282 4e-75
pir||H82930 cysteinyl-tRNA synthetase UU123 [imported] - Ureapla... 262 7e-69
sp|O51545|SYC_BORBU CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LI... 258 8e-68
sp|O07045|SYC_AZOBR CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LI... 252 8e-66
sp|Q09860|YAF6_SCHPO PUTATIVE CYSTEINYL-TRNA SYNTHETASE C29E6.06... 251 1e-65
sp|P47495|SYC_MYCGE CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LI... 249 5e-65
emb|CAC16398.1| (AJ276505) cysteinyl-tRNA-synthetase [Mus muscul... 249 7e-65
emb|CAC16403.1| (AJ276796) CysRS protein [Mus musculus] 249 7e-65
gi|10835051 cysteinyl-tRNA synthetase [Homo sapiens] >gi|1144068... 246 5e-64
gb|AAG00579.1|AF288207_1 (AF288207) cysteinyl-tRNA synthetase [H... 246 5e-64
gb|AAG37230.1| (AF299082) cysteinyl-tRNA synthetase [Giardia int... 245 1e-63
sp|P75423|SYC_MYCPN CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LI... 243 4e-63
gi|6324082 Ynl247wp [Saccharomyces cerevisiae] >gi|1730840|sp|P5... 242 7e-63
gb|AAC64633.1| (AF077541) contains similarity to class-I aminoac... 240 2e-62
gb|AAG03366.1| (AF024666) CysS [Corynebacterium striatum] 240 4e-62
gb|AAA73901.1| (L06845) cysteinyl-tRNA synthetase [Homo sapiens] 239 5e-62
sp|P49589|SYC_HUMAN CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LI... 239 5e-62
emb|CAA67901.1| (X99587) cysteine tRNA synthetase [Azospirillum ... 239 5e-62
gb|AAD34748.1| (AF132160) unknown [Drosophila melanogaster] >gi|... 236 5e-61
dbj|BAA29032.1| (AB015589) cysteinyl-tRNA synthetase [Mus musculus] 232 8e-60
sp|O33264|SYC2_MYCTU CYSTEINYL-TRNA SYNTHETASE 2 (CYSTEINE--TRNA... 224 2e-57
sp|Q49784|SYC2_MYCLE CYSTEINYL-TRNA SYNTHETASE 2 (CYSTEINE--TRNA... 213 3e-54
pir||S72854 cysteine--tRNA ligase (EC 6.1.1.16) - Mycobacterium ... 186 4e-46
gb|AAD09434.1| (U09230) cysteinyl-tRNA synthetase [Buchnera aphi... 143 6e-33
sp|P46241|SYC_BUCAP CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LI... 143 6e-33
sp|P77986|SYC_STAXY CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LI... 140 3e-32
pir||C53739 vacA 5'-region protein - Helicobacter pylori (ATCC 4... 87 4e-16
gb|AAC64627.1| (AF077541) contains similarity to class-I aminoac... 75 1e-12
>pir||A75052 cysteinyl-tRNA synthetase (cyss) PAB0931 - Pyrococcus abyssi
(strain Orsay) >gi|5458823|emb|CAB50310.1| (AJ248287)
cysteinyl-tRNA synthetase (cysS) [Pyrococcus abyssi]
Length = 477
Score = 983 bits (2514), Expect = 0.0
Identities = 477/477 (100%), Positives = 477/477 (100%)
Query: 1 MGIKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGF 60
MGIKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGF
Sbjct: 1 MGIKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGF 60
Query: 61 TVLMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHID 120
TVLMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHID
Sbjct: 61 TVLMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHID 120
Query: 121 DIIEFIKKLKEKGYAYEGSDGVYFEVQKFKDYGKLSGVKIEELRKGARVEPGEGKKNPED 180
DIIEFIKKLKEKGYAYEGSDGVYFEVQKFKDYGKLSGVKIEELRKGARVEPGEGKKNPED
Sbjct: 121 DIIEFIKKLKEKGYAYEGSDGVYFEVQKFKDYGKLSGVKIEELRKGARVEPGEGKKNPED 180
Query: 181 FALWKKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIA 240
FALWKKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIA
Sbjct: 181 FALWKKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIA 240
Query: 241 QSEACFGHEWVRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHYRS 300
QSEACFGHEWVRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHYRS
Sbjct: 241 QSEACFGHEWVRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHYRS 300
Query: 301 PLDYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREARKKFYDA 360
PLDYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREARKKFYDA
Sbjct: 301 PLDYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREARKKFYDA 360
Query: 361 MDDDFNTAEALKAVFEVSNAINKYILEVDKPKESILRKALEFFKVVSEVFGIFEDYFKEE 420
MDDDFNTAEALKAVFEVSNAINKYILEVDKPKESILRKALEFFKVVSEVFGIFEDYFKEE
Sbjct: 361 MDDDFNTAEALKAVFEVSNAINKYILEVDKPKESILRKALEFFKVVSEVFGIFEDYFKEE 420
Query: 421 KKGEEEKLIELLVEVRKQLRKEKRFDLADKIREELRKLGIQLEDKGQETVWKRVKVS 477
KKGEEEKLIELLVEVRKQLRKEKRFDLADKIREELRKLGIQLEDKGQETVWKRVKVS
Sbjct: 421 KKGEEEKLIELLVEVRKQLRKEKRFDLADKIREELRKLGIQLEDKGQETVWKRVKVS 477
>sp|O58370|SYC_PYRHO CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LIGASE) (CYSRS)
>gi|7437717|pir||D71108 cysteine--tRNA ligase (EC
6.1.1.16) - Pyrococcus horikoshii
>gi|3257043|dbj|BAA29726.1| (AP000003) 476aa long
hypothetical cysteinyl-tRNA synthetase [Pyrococcus
horikoshii]
Length = 476
Score = 892 bits (2281), Expect = 0.0
Identities = 415/476 (87%), Positives = 456/476 (95%)
Query: 1 MGIKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGF 60
M +++YNTLT++KEE KP+ +GEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEH+G+
Sbjct: 1 MTLRIYNTLTKQKEEFKPINEGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHKGY 60
Query: 61 TVLMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHID 120
+VLMVMNFTDIDDKII+RA+ETGEDP KLAE+FIKVFLEDM ALKVKPADIYPRVTEHI+
Sbjct: 61 SVLMVMNFTDIDDKIIRRAKETGEDPAKLAEKFIKVFLEDMKALKVKPADIYPRVTEHIE 120
Query: 121 DIIEFIKKLKEKGYAYEGSDGVYFEVQKFKDYGKLSGVKIEELRKGARVEPGEGKKNPED 180
DII+FI++LKEKGYAYEGSDGVYFEVQKFK+YGKLSGVK+EELRKGARVEPGEGKKNPED
Sbjct: 121 DIIQFIERLKEKGYAYEGSDGVYFEVQKFKEYGKLSGVKLEELRKGARVEPGEGKKNPED 180
Query: 181 FALWKKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIA 240
FALWKKAKPGEPKW+SPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIA
Sbjct: 181 FALWKKAKPGEPKWESPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIA 240
Query: 241 QSEACFGHEWVRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHYRS 300
QSEACFGHEWV YWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIR FVLQKHYRS
Sbjct: 241 QSEACFGHEWVHYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRFFVLQKHYRS 300
Query: 301 PLDYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREARKKFYDA 360
PLDY+EEGLQHAKNNLERLYNTLENIRIAM NAEL+Y W E DF+AY +I+EAR+KFY+A
Sbjct: 301 PLDYSEEGLQHAKNNLERLYNTLENIRIAMENAELAYTWDENDFKAYNSIKEARRKFYEA 360
Query: 361 MDDDFNTAEALKAVFEVSNAINKYILEVDKPKESILRKALEFFKVVSEVFGIFEDYFKEE 420
MDDDFNTAEALKAVFEVSNAINKYI E +KPKES+LRKA EFF+ V E+FGIFE+YFKEE
Sbjct: 361 MDDDFNTAEALKAVFEVSNAINKYITEAEKPKESVLRKAWEFFRTVGEIFGIFEEYFKEE 420
Query: 421 KKGEEEKLIELLVEVRKQLRKEKRFDLADKIREELRKLGIQLEDKGQETVWKRVKV 476
K EEEKLIELL++VR +LRKE++F+LADKIREELRKLGIQLEDKG+ET+WKR+KV
Sbjct: 421 KAKEEEKLIELLIQVRAELRKERKFELADKIREELRKLGIQLEDKGKETIWKRIKV 476
>pir||T47278 cysteine--tRNA ligase (EC 6.1.1.16) [validated] - Methanococcus
maripaludis >gi|6599476|gb|AAF18750.1|AF163997_1
(AF163997) cysteinyl-tRNA synthetase [Methanococcus
maripaludis]
Length = 476
Score = 661 bits (1687), Expect = 0.0
Identities = 295/475 (62%), Positives = 383/475 (80%), Gaps = 1/475 (0%)
Query: 3 IKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGFTV 62
+KVYNTLTRK+EE K L EV+MYVCGP VYD HLGH RTY++ D+IRRYLEH G+TV
Sbjct: 2 LKVYNTLTRKEEEFKTLNKNEVKMYVCGPPVYDTTHLGHGRTYVSLDIIRRYLEHIGYTV 61
Query: 63 LMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHIDDI 122
+V+NFTDIDDKIIKRA E G+DP +++E+FIKVFL+DM LKVKPADIYP+VTEHI +I
Sbjct: 62 NLVINFTDIDDKIIKRAYEKGKDPKEISEQFIKVFLDDMATLKVKPADIYPKVTEHISEI 121
Query: 123 IEFIKKLKEKGYAYEGSDGVYFEVQKFKDYGKLSGVKIEELRKGARVEPGEGKKNPEDFA 182
I FI++L EKG+AY+ DGVYFEV+KFK+YGKLS + +E+L GARVE E KKN +DFA
Sbjct: 122 IAFIERLIEKGFAYKTEDGVYFEVKKFKNYGKLSNINLEDLVSGARVETSEKKKNQKDFA 181
Query: 183 LWKKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIAQS 242
LWK AKPGEPKW+SP+G+GRPGWHIECS MSSKYLGE FDIHGGG DL FPHHENEIAQS
Sbjct: 182 LWKTAKPGEPKWESPFGKGRPGWHIECSAMSSKYLGEQFDIHGGGRDLSFPHHENEIAQS 241
Query: 243 EACFGHEWVRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHYRSPL 302
A G +WV YW+HTGFVMV GEKMSKSLGNF+T+ ++ + YSPE++R F +Q+HYRSP+
Sbjct: 242 SAYSGKDWVNYWIHTGFVMVNGEKMSKSLGNFITIGDISKEYSPEILRFFFIQRHYRSPI 301
Query: 303 DYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREARKKFYDAMD 362
DYT E + H KNNLE++YN +ENIRI++ +E S W E +F Y+ ++ ++ FY+AM+
Sbjct: 302 DYTAESMNHVKNNLEKIYNVIENIRISLEKSEKSRIWGENEFLLYDILKNSKNNFYNAMN 361
Query: 363 DDFNTAEALKAVFEVSNAINKYILEVDKPKESILRKALEFFKVVSEVFGIFEDYFKEEKK 422
DFNT EALK+VFEVSN +NKY+ + P E +L KAL+F+K++ E+FG+FE+YFKE +
Sbjct: 362 SDFNTVEALKSVFEVSNGVNKYLSLTETPSEGLLLKALDFYKIIGEIFGLFENYFKESSE 421
Query: 423 GEEEKLIELLVEVRKQLRKEKRFDLADKIREELRKLGIQLEDKGQE-TVWKRVKV 476
EE+ ++ L+E+R LR +K ++++DKIR+ L+ LG Q+ED +E TV+K++ +
Sbjct: 422 SNEEEFVKFLIELRSDLRLQKNYEMSDKIRDGLKNLGYQIEDNPKEGTVFKKINI 476
>sp|Q06752|SYC_BACSU CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LIGASE) (CYSRS)
>gi|541406|pir||C53402 cysteine--tRNA ligase (EC
6.1.1.16) cysS - Bacillus subtilis
>gi|289284|gb|AAA21798.1| (L14580) cysteinyl-tRNA
synthetase [Bacillus subtilis]
>gi|467482|dbj|BAA05328.1| (D26185) cysteinyl-tRNA
synthetase [Bacillus subtilis]
>gi|499303|emb|CAA52167.1| (X73989) cysteine--tRNA
ligase [Bacillus subtilis] >gi|2632361|emb|CAB11870.1|
(Z99104) cysteinyl-tRNA synthetase [Bacillus subtilis]
Length = 466
Score = 480 bits (1221), Expect = e-134
Identities = 233/476 (48%), Positives = 320/476 (66%), Gaps = 15/476 (3%)
Query: 1 MGIKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGF 60
M I +YNTLTR+KE PL +G+V+MYVCGPTVY+Y H+G+AR I +D +R YLE++G+
Sbjct: 1 MTITLYNTLTRQKETFVPLEEGKVKMYVCGPTVYNYIHIGNARPAIVYDTVRNYLEYKGY 60
Query: 61 TVLMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHID 120
V V NFTD+DDK+IK A E GED ++ERFIK + ED+ AL + AD++PRV E++D
Sbjct: 61 DVQYVSNFTDVDDKLIKAANELGEDVPTISERFIKAYFEDVGALGCRKADLHPRVMENMD 120
Query: 121 DIIEFIKKLKEKGYAYEGSDGVYFEVQKFKDYGKLSGVKIEELRKGARVEPGEGKKNPED 180
IIEF+ +L +KGYAYE VYF+ + F+ YGKLS I+ELR GAR+ GE K++ D
Sbjct: 121 AIIEFVDQLVKKGYAYESEGDVYFKTRAFEGYGKLSQQSIDELRSGARIRVGEKKEDALD 180
Query: 181 FALWKKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIA 240
FALWK AK GE WDSPWG+GRPGWHIECS M KYLG+ DIH GG DL FPHHENEIA
Sbjct: 181 FALWKAAKEGEISWDSPWGKGRPGWHIECSAMVKKYLGDQIDIHAGGQDLTFPHHENEIA 240
Query: 241 QSEACFGHEWVRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHYRS 300
QSEA G + +YWLH G++ + EKMSKSLGNFV V ++++++ P+++R F+L HYR
Sbjct: 241 QSEALTGKTFAKYWLHNGYINIDNEKMSKSLGNFVLVHDIIKQHDPQLLRFFMLSVHYRH 300
Query: 301 PLDYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREARKKFYDA 360
P++Y+EE L++ K+ RL N++ + + S +E D + E + E RK F +
Sbjct: 301 PINYSEELLENTKSAFSRLKTAYSNLQHRLNS---STNLTEDDDQWLEKVEEHRKAFEEE 357
Query: 361 MDDDFNTAEALKAVFEVSNAINKYILEVDKPKESILRKALEFFKVVSEVFGIFEDYFKEE 420
MDDDFNTA A+ +F+++ N Y L+ D + ++ +E F + V G
Sbjct: 358 MDDDFNTANAISVLFDLAKHAN-YYLQKDHTADHVITAFIEMFDRIVSVLGF-------- 408
Query: 421 KKGEEEKL---IELLVEVRKQLRKEKRFDLADKIREELRKLGIQLEDKGQETVWKR 473
GE+E L IE L+E R + R+ + F L+D+IR++L+ + I LED Q T WKR
Sbjct: 409 SLGEQELLDQEIEDLIEKRNEARRNRDFALSDQIRDQLKSMNIILEDTAQGTRWKR 464
>sp|O67163|SYC_AQUAE CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LIGASE) (CYSRS)
>gi|7437719|pir||H70391 cysteine--tRNA ligase (EC
6.1.1.16) - Aquifex aeolicus >gi|2983551|gb|AAC07125.1|
(AE000721) cysteinyl-tRNA synthetase [Aquifex aeolicus]
Length = 495
Score = 474 bits (1208), Expect = e-133
Identities = 239/492 (48%), Positives = 323/492 (65%), Gaps = 20/492 (4%)
Query: 1 MGIKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGF 60
M +++YNTL+ K EE P+ +V +Y CG TVYD H+GH R+ I FDV RR+LEH G+
Sbjct: 1 MSLRIYNTLSGKVEEFVPINPPKVLIYTCGVTVYDDSHVGHGRSLIVFDVFRRFLEHLGY 60
Query: 61 TVLMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHID 120
V V NFTD+DDKII RA++ D +A+R+I + DM ++V+PAD+ PRVTEHI
Sbjct: 61 QVKFVRNFTDVDDKIINRAKQECTDFMTIADRYIARYYVDMENIRVRPADVEPRVTEHIP 120
Query: 121 DIIEFIKKLKEKGYAYEGSDGVYFEVQKFKDYGKLSGVKIEELRKGARVEPGEGKKNPED 180
+IIE I+KL EKGYAY VYF V+KFKDYGKLS IEEL GARVEP E K++P D
Sbjct: 121 EIIEVIQKLVEKGYAYVVEGDVYFSVKKFKDYGKLSKRDIEELIAGARVEPSEKKRDPLD 180
Query: 181 FALWKKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIA 240
FALWK +K GEP WDSPWG+GRPGWH EC M K+LGE+ DIHGGG DL+FPHHENEIA
Sbjct: 181 FALWKASKAGEPAWDSPWGKGRPGWHTECVAMVFKHLGETIDIHGGGLDLVFPHHENEIA 240
Query: 241 QSEACFGHEWVRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHYRS 300
Q+EA G + RYW+H G V V G+KMSKSLGN+VT+RE+ +Y P+V+RL VL HYRS
Sbjct: 241 QAEAITGKPFARYWMHNGLVTVGGQKMSKSLGNYVTLREVYTKYHPDVLRLLVLFTHYRS 300
Query: 301 PLDYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREARKKFYDA 360
PLD++ E ++ ERL N +E++ + ++ ++ YE ++E + FY +
Sbjct: 301 PLDFSWEKMEETLKAYERLKNAIEDLEL-LKKLQVVESKEGGTHPLYEQVKEFEENFYAS 359
Query: 361 MDDDFNTAEALKAVFEVSNAINKYILE-------VDKPKESILRKALEFFKVVSEVFGIF 413
+ DDFNT EAL V+++ +NK + D+ + + + ++FG+
Sbjct: 360 LSDDFNTPEALSHVYKLVGELNKVKNKAYSEGKITDRELSAYEFASKSLLNTMKKIFGLL 419
Query: 414 EDYFKE-------EKKGE-----EEKLIELLVEVRKQLRKEKRFDLADKIREELRKLGIQ 461
ED + E E++ E +EKLI++L+E R RKEK F +AD IR++L++LGI
Sbjct: 420 EDLYPECKVERVVERELEAGQVFDEKLIQILIEARNIARKEKVFKVADYIRDKLKELGIV 479
Query: 462 LEDKGQETVWKR 473
LED T WK+
Sbjct: 480 LEDTPAGTKWKK 491
>sp|Q9WZH8|SYC_THEMA CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LIGASE) (CYSRS)
>gi|7437723|pir||E72341 cysteine--tRNA ligase (EC
6.1.1.16) - Thermotoga maritima (strain MSB8)
>gi|4981244|gb|AAD35801.1|AE001743_3 (AE001743)
cysteinyl-tRNA synthetase [Thermotoga maritima]
Length = 460
Score = 474 bits (1206), Expect = e-132
Identities = 241/472 (51%), Positives = 326/472 (69%), Gaps = 32/472 (6%)
Query: 3 IKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGFTV 62
+++ NTLT KKEE P++ G VRMYVCGPTVYD H+G+AR + FDV RRYLE+RG+ V
Sbjct: 1 MRITNTLTGKKEEFVPIQPGVVRMYVCGPTVYDLIHVGNARPALVFDVFRRYLEYRGYRV 60
Query: 63 LMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHIDDI 122
+MV NFTDIDDKII +A + G D +A+ FI + D +AL ++PA+ +PR T+ ++DI
Sbjct: 61 IMVQNFTDIDDKIINKANQLGVDYKTVADTFIAEYWRDAHALGIRPANFHPRTTDFVEDI 120
Query: 123 IEFIKKLKEKGYAYEGSDGVYFEVQKFKDYGKLSGVKIEELRKGARVEPGEGKKNPEDFA 182
+E I+KL EKG+AY+ GVYF+V+KF+ YG+LS KIE+L GARVE E KK+P DF+
Sbjct: 121 VEIIEKLVEKGFAYQTETGVYFDVRKFEKYGELSKKKIEDLIAGARVEVDETKKSPLDFS 180
Query: 183 LWKKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIAQS 242
LWKKAKPGEP W SPWGEGRPGWHIEC+VMS K LGESFDIH GG DL+FPHHENE AQ+
Sbjct: 181 LWKKAKPGEPCWKSPWGEGRPGWHIECTVMSVKILGESFDIHAGGEDLVFPHHENEKAQA 240
Query: 243 EACFGHEWVRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHYRSPL 302
EA G + RYW+H G V G+KMSKS GN TVRE ++RY + +R +L KHYRSP+
Sbjct: 241 EALTGKVFARYWMHNGMVRFLGDKMSKSTGNIFTVREAVKRYGRDGLRYMILSKHYRSPM 300
Query: 303 DYTEEGLQHAKNNLERLYNTL------ENIRIAMRNAELSYKWSEKDFEAYEAIREARKK 356
D++EE LQ ++R++ L +I I RNA YE E +
Sbjct: 301 DFSEELLQDYSRAVKRVWEILGRYEKSGDIGIPKRNA------------VYE---EYVNR 345
Query: 357 FYDAMDDDFNTAEALKAVFEVSNAINKYILEVDKPKESILRKALEFFKVV----SEVFGI 412
F +A+DDDFNT A+ +FE++ ++K + + D+ AL ++ ++ V G+
Sbjct: 346 FVEALDDDFNTPVAVSLIFELARNLSKAMDDNDR------EDALLYYHLIRREFGPVLGL 399
Query: 413 FEDYFKEEKKGEEEKLIELLVEVRKQLRKEKRFDLADKIREELRKLGIQLED 464
F D +E+K+ E+L++LL+EVR LRKEKR+DL+D+IR+ LR++GI L+D
Sbjct: 400 F-DLNEEKKEVSSEELLKLLIEVRDVLRKEKRYDLSDRIRDRLREIGIILKD 450
>sp|Q9KGF4|SYC_BACHD CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LIGASE) (CYSRS)
>gi|10172723|dbj|BAB03830.1| (AP001507) cysteinyl-tRNA
synthetase [Bacillus halodurans]
Length = 466
Score = 469 bits (1194), Expect = e-131
Identities = 235/477 (49%), Positives = 322/477 (67%), Gaps = 17/477 (3%)
Query: 1 MGIKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGF 60
M I+V+N+LTRKKE PL +G+V+MYVCGPTVY+Y H+G+AR I +D+IRRYL++RG+
Sbjct: 1 MAIQVFNSLTRKKEPFVPLEEGKVKMYVCGPTVYNYIHIGNARPPIVYDMIRRYLKYRGY 60
Query: 61 TVLMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHID 120
VL V NFTD+DDKII+ A E GED +A RFI+ + +D +AL V AD +PRVTE +
Sbjct: 61 EVLFVSNFTDVDDKIIRVANELGEDVFAVANRFIEAYKQDTSALGVLEADHHPRVTETMS 120
Query: 121 DIIEFIKKLKEKGYAYEGSDGVYFEVQKFKDYGKLSGVKIEELRKGARVEPGEGKKNPED 180
+II FI+ L+EKGYAYE VYF +KFK+YGKLS I++L GAR+E E K++P D
Sbjct: 121 EIISFIRVLEEKGYAYEQGGDVYFRTRKFKEYGKLSAQSIDDLLSGARIEVDERKEDPLD 180
Query: 181 FALWKKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIA 240
F LWK AK GE WDSPWG+GRPGWHIECS M KYLG++ DIH GG DL FPHHENEIA
Sbjct: 181 FVLWKAAKEGEVSWDSPWGKGRPGWHIECSAMVKKYLGDTIDIHAGGQDLKFPHHENEIA 240
Query: 241 QSEACFGHEWVRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHYRS 300
QSE G YWLH GF+ + EKMSKSLGN V E+++++S EV+R F+L HYRS
Sbjct: 241 QSECMTGKPMANYWLHNGFINLDNEKMSKSLGNVVLANEMIRQHSAEVLRFFMLSAHYRS 300
Query: 301 PLDYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEA----YEAIREARKK 356
P+++++E L+ AK LERL + ++ ++ + DF E I E R +
Sbjct: 301 PINFSDELLEGAKRGLERLQTAVSSLVHRLQES--------ADFGGTEPWLERIDEFRGR 352
Query: 357 FYDAMDDDFNTAEALKAVFEVSNAINKYILEVDKPKESILRKALEFFKVVSEVFGIFEDY 416
F + MDDDFN+A + +F+++ N+Y+ E ++ +++L+ ++ F + V G+ +
Sbjct: 353 FIEEMDDDFNSANGIAVLFDLAKEANRYLRE-EQTSKAVLQSFIDLFNELGGVLGVTLN- 410
Query: 417 FKEEKKGEEEKLIELLVEVRKQLRKEKRFDLADKIREELRKLGIQLEDKGQETVWKR 473
++E+ +EE IE L+E R + RK K F AD IR++L+ GI LED Q WKR
Sbjct: 411 -RQEELLDEE--IERLIEERNEARKAKNFQRADDIRDQLKAEGIILEDTPQGVRWKR 464
>sp|Q9YBK6|SYC_AERPE CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LIGASE) (CYSRS)
>gi|7437721|pir||C72538 probable cysteinyl-tRNA
synthetase APE1592 - Aeropyrum pernix (strain K1)
>gi|5105279|dbj|BAA80592.1| (AP000062) 475aa long
hypothetical cysteinyl-tRNA synthetase [Aeropyrum
pernix]
Length = 475
Score = 455 bits (1157), Expect = e-127
Identities = 229/475 (48%), Positives = 310/475 (65%), Gaps = 9/475 (1%)
Query: 3 IKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGFTV 62
I+V+NTL R+KE P V MYVCGPTVYDY H+GHART+ FD I+RYL RG+ V
Sbjct: 5 IRVFNTLGRRKEVFNPYSPPLVGMYVCGPTVYDYTHIGHARTFTVFDAIKRYLRLRGYDV 64
Query: 63 LMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHIDDI 122
V N TDIDDKII RA+E G D ++ + + +LE + +L ++ D +PRVT+HI DI
Sbjct: 65 FHVQNITDIDDKIINRAREEGRDWREIVREYSRDYLEGLGSLGIQ-IDHHPRVTDHISDI 123
Query: 123 IEFIKKLKEKGYAYEGSDG-VYFEVQKFKDYGKLSGVKIEELRKGARVEPGEGKKNPEDF 181
I FI+ L EKGYAY G VYFEV K+ YG LSG +E + E KK+P DF
Sbjct: 124 IRFIEGLIEKGYAYVAESGSVYFEVDKYPGYGMLSGHLSKEAWRQEEDVLHE-KKSPYDF 182
Query: 182 ALWKKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIAQ 241
ALWK AKPGEP W+SPWG GRPGWHIECSVMSS+YLG DIHGGG DL+FPHHENE AQ
Sbjct: 183 ALWKAAKPGEPSWESPWGRGRPGWHIECSVMSSRYLGSRIDIHGGGVDLVFPHHENERAQ 242
Query: 242 SEACFGHEWVRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHYRSP 301
SE+ FGH WVRYWLH ++ +KGEKMSKSLGN + +RE L+ + P +RL++L HYRS
Sbjct: 243 SESYFGHRWVRYWLHASYLTIKGEKMSKSLGNIIPLREALREWGPGPLRLWLLSSHYRSN 302
Query: 302 LDYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREARKKFYDAM 361
LDY+EE L + ERL ++I + AE + E + E E ++ +++++AM
Sbjct: 303 LDYSEEALGQYRRLYERLRQAADSIGRRLERAEPKGRLGEGELETVERLKGVVRRWHEAM 362
Query: 362 DDDFNTAEALKAVFEVSNAINKYILEVDKPKE-SILRKALEFFKVVSEVFGIFEDYF--K 418
DDFN +A+ +++E + Y EV++ + ++L + + V+ D +
Sbjct: 363 SDDFNMGKAMSSLWEFTTI---YFREVEQTESYTLLWLSWRILTGFNSVYAFAPDIVEAR 419
Query: 419 EEKKGEEEKLIELLVEVRKQLRKEKRFDLADKIREELRKLGIQLEDKGQETVWKR 473
++ E+ L++ LV+VR +LR+ K +DLAD+IR L +LG L DKG++T W+R
Sbjct: 420 RPERSLEDSLVQALVDVRSELRRRKMYDLADEIRSRLAQLGFVLHDKGEKTEWRR 474
>emb|CAB71305.1| (AJ130879) cysteinyl tRNA synthetase [Clostridium sticklandii]
Length = 443
Score = 453 bits (1152), Expect = e-126
Identities = 218/449 (48%), Positives = 309/449 (68%), Gaps = 7/449 (1%)
Query: 26 MYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGFTVLMVMNFTDIDDKIIKRAQETGED 85
MYVCGPTVY++ H+G+AR ++ FD R Y+E+RG+ V V NFTD+DDKIIKRA E G
Sbjct: 1 MYVCGPTVYNFFHIGNARPFMIFDAFRNYMEYRGYEVTYVQNFTDVDDKIIKRANEEGIS 60
Query: 86 PGKLAERFIKVFLEDMNALKVKPADIYPRVTEHIDDIIEFIKKLKEKGYAYEGSDGVYFE 145
P ++AE++I + +D +AL +K A ++PRVTE+I++II FI+ L KG+AYE + VYF
Sbjct: 61 PIEVAEKYIAEYFKDADALGIKRATVHPRVTENIENIITFIEDLISKGFAYELNGDVYFN 120
Query: 146 VQKFKDYGKLSGVKIEELRKGARVEPGEGKKNPEDFALWKKAKPGEPKWDSPWGEGRPGW 205
Q +K+YGKLS +EEL GAR++ + KK+P DFALWK K GE W SPWGEGRPGW
Sbjct: 121 SQAYKEYGKLSKQNLEELNLGARIDVNDEKKHPIDFALWKAKKEGEIGWQSPWGEGRPGW 180
Query: 206 HIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIAQSEACFGHEWVRYWLHTGFVMVKGE 265
HIECSVMS++YLG++ DIH GG DLIFPHHENEIAQSEA G ++ RYW+H G++ V +
Sbjct: 181 HIECSVMSARYLGDTIDIHAGGQDLIFPHHENEIAQSEARSGKQFARYWMHNGYINVDNQ 240
Query: 266 KMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHYRSPLDYTEEGLQHAKNNLERLYNTLEN 325
KMSKSLGNF TVR++L +S +VIR F+L HYR+P+++++E + AK +ERL N+ E
Sbjct: 241 KMSKSLGNFFTVRDILSEFSGQVIRFFLLSAHYRNPVNFSKELILQAKAGMERLANSKER 300
Query: 326 IRIAMRNAELSYKWSEKDFEAYEAIREARKKFYDAMDDDFNTAEALKAVFEVSNAINKYI 385
+ + +A+ + +E + E A+ R +F +AMDDD NTA+A+ +FE++ N +
Sbjct: 301 LVFTISHAK--GQMNESELELVSALENHRDRFIEAMDDDINTADAISIIFELARFSNTNV 358
Query: 386 LEVDKPKESILRKALEFFKVVSEVFGIFEDYFKEEKKGEEEKLIELLVEVRKQLRKEKRF 445
E S L A + + +E+ G+ E+ + + IE L++ R + +K K F
Sbjct: 359 TE-----NSSLEWAEKNLSLFNELTGVLNIIKAEDTDSNDNEQIEKLIKDRVEAKKNKDF 413
Query: 446 DLADKIREELRKLGIQLEDKGQETVWKRV 474
LAD IR+EL+ +GI++ED Q T WK+V
Sbjct: 414 ALADAIRDELKSMGIEIEDTRQGTKWKKV 442
>gb|AAK42442.1| Cysteinyl-tRNA synthetase (cysS) [Sulfolobus solfataricus]
Length = 470
Score = 447 bits (1138), Expect = e-124
Identities = 221/471 (46%), Positives = 318/471 (66%), Gaps = 8/471 (1%)
Query: 3 IKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGFTV 62
I+VYN+L RK EE + V+MYVCGPTVYDY H+GH RT++ FD I RYL RG+TV
Sbjct: 5 IRVYNSLGRKLEEFGTVEPNLVKMYVCGPTVYDYVHIGHGRTFVVFDAISRYLRLRGYTV 64
Query: 63 LMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHIDDI 122
+ V N TDIDDKIIK++QE G+D ++ + F K +L+ ++ LKVK DI+PRVT+HI +I
Sbjct: 65 IRVQNITDIDDKIIKKSQEIGKDWNEIVDYFTKDYLDMLSQLKVK-IDIHPRVTQHIREI 123
Query: 123 IEFIKKLKEKGYAYEGSDG-VYFEVQKFKDYGKLSGVKIEELRKGARVEPGEGKKNPEDF 181
I+F+++L +KG+AY G VYF+V + +YG+LS K EE +G E + KK+ DF
Sbjct: 124 IDFVQRLIDKGHAYVAPSGSVYFDVDTYPNYGELSNTKKEEWNQGE--EFVKEKKHSYDF 181
Query: 182 ALWKKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIAQ 241
ALWK KPGEP W+SPWG+GRPGWHIECS MS++YLGE FDIHGGG DLIFPHHENE AQ
Sbjct: 182 ALWKAWKPGEPYWESPWGKGRPGWHIECSTMSTRYLGERFDIHGGGADLIFPHHENERAQ 241
Query: 242 SEACFGHEWVRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHYRSP 301
+EA G +WV YW+H+ FV ++ EKMSKSLGN + + E ++++ P V+R + L HYRSP
Sbjct: 242 TEALIGEKWVTYWVHSAFVTIRKEKMSKSLGNIIPLNEAIKKWGPSVLRYWYLTSHYRSP 301
Query: 302 LDYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREARKKFYDAM 361
+D++EE L+ AK+ L+R+ +++ IR + Y + D + Y I F+ AM
Sbjct: 302 IDFSEEALEQAKSALQRIKDSMAIIRDVISEGPKFYV-KDDDIKVYREILNNLNNFHTAM 360
Query: 362 DDDFNTAEALKAVFEVSNAINKYILEVDKPKESILRKALEFFKVVSEVFGIFEDYFKEEK 421
+DF+T+ AL + E+ + + ++L A E K +EVFG+ ++ F
Sbjct: 361 SNDFDTSTALSYIHEIVRLVFSTLQYSRDFLGAML--AFETLKQFNEVFGVMDEEF-YPT 417
Query: 422 KGEEEKLIELLVEVRKQLRKEKRFDLADKIREELRKLGIQLEDKGQETVWK 472
+ K+I+ +V++R QLR+ K ++++DKIREEL K G+++ D ++ W+
Sbjct: 418 YDKMYKIIDAVVDIRNQLRQMKLYEISDKIREELLKAGVRILDSKDKSTWR 468
>pir||G83421 cysteinyl-tRNA synthetase PA1795 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9947777|gb|AAG05184.1|AE004605_6 (AE004605)
cysteinyl-tRNA synthetase [Pseudomonas aeruginosa]
Length = 460
Score = 445 bits (1133), Expect = e-124
Identities = 232/475 (48%), Positives = 304/475 (63%), Gaps = 24/475 (5%)
Query: 3 IKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGFTV 62
+++YNTL++ KE PL +VRMYVCG TVYDY HLGH R+ +AFDVI R+L HRG+ +
Sbjct: 2 LQIYNTLSKTKEVFTPLVGNQVRMYVCGMTVYDYCHLGHGRSMVAFDVITRWLRHRGYDL 61
Query: 63 LMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHIDDI 122
V N TDIDDKII RA E GE L ER I ED L + D PR T+HI +
Sbjct: 62 TYVRNITDIDDKIINRANENGEPFDVLTERMIAAMHEDEARLNILKPDQEPRATDHIAGM 121
Query: 123 IEFIKKLKEKGYAYEGSDG-VYFEVQKFKDYGKLSGVKIEELRKGARVEPGEGKKNPEDF 181
I+ L +KGYAY +G VY+ V KF YGKLS ++E+LR GAR+EPGE K++P DF
Sbjct: 122 HAMIQTLIDKGYAYAPGNGDVYYRVGKFAGYGKLSRRRVEDLRIGARIEPGEAKEDPLDF 181
Query: 182 ALWKKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIAQ 241
LWK AKPGEP W SPWGEGRPGWHIECSVMS+ LG+SFDIHGGGNDL FPHHENEIAQ
Sbjct: 182 VLWKGAKPGEPSWSSPWGEGRPGWHIECSVMSTCCLGDSFDIHGGGNDLEFPHHENEIAQ 241
Query: 242 SEACFGHEWVRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHYRSP 301
SEA G + + WLH G + + GEKMSKSLGNF T+RE+L++Y PEV+R ++ HYRSP
Sbjct: 242 SEAATGKPYAKSWLHCGMITINGEKMSKSLGNFFTIREVLEKYHPEVVRYLLIASHYRSP 301
Query: 302 LDYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREARKKFYDAM 361
++Y+EE L+ AK L+R YN L+ + A EA E + ++F AM
Sbjct: 302 INYSEENLREAKAALDRFYNALKGLPEA------------APAEAAEYV----ERFAAAM 345
Query: 362 DDDFNTAEALKAVFEVSNAINKYILEVDKPKESILRKALEFFKVVSEVFGIFEDYFKEEK 421
DDDFNTA A +FE++ +N+ + E D + L L+ + V + + F +
Sbjct: 346 DDDFNTAGACSVLFELAREVNR-LRESDLSAAAALAARLKQLAGLLGVLQLEPEAFLQ-- 402
Query: 422 KGEEEKL----IELLVEVRKQLRKEKRFDLADKIREELRKLGIQLEDKGQETVWK 472
G E K+ +E L++ R + R K + +D+IR++L +G+ LED T W+
Sbjct: 403 AGAEGKVDAAEVEALIQARLEARAAKNWAESDRIRDQLTAMGVVLEDGKGGTTWR 457
>gi|11498023 cysteinyl-tRNA synthetase (cysS) [Archaeoglobus fulgidus]
>gi|3122884|sp|O29836|SYC_ARCFU CYSTEINYL-TRNA
SYNTHETASE (CYSTEINE--TRNA LIGASE) (CYSRS)
>gi|7428478|pir||C69301 cysteine--tRNA ligase (EC
6.1.1.16) - Archaeoglobus fulgidus
>gi|2650218|gb|AAB90823.1| (AE001076) cysteinyl-tRNA
synthetase (cysS) [Archaeoglobus fulgidus]
Length = 467
Score = 444 bits (1129), Expect = e-123
Identities = 240/477 (50%), Positives = 318/477 (66%), Gaps = 19/477 (3%)
Query: 3 IKVYNTLTRKKEELKPLRDGE-VRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGFT 61
++VYNTL+RK E+L+ + DG+ V+MYVCG T YDY H+GHAR+ + FDV RRYLE+ G+
Sbjct: 1 MEVYNTLSRKIEKLEDIVDGKRVKMYVCGITAYDYSHIGHARSAVFFDVFRRYLEYLGYE 60
Query: 62 VLMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHIDD 121
V+ V NFTD+DDKII RA + G+ ++AE+FI+ +L+DM AL VK P+VTEHI D
Sbjct: 61 VVYVQNFTDVDDKIINRAVKEGKTQKEVAEKFIEEYLKDMEALNVKKPTYQPKVTEHIPD 120
Query: 122 IIEFIKKLKEKGYAYEGSDGVYFEVQKFKDYGKLSGVKIEELRKGARVEPGEGKKNPEDF 181
IIEFI+ L EKGYAY VYF V F+ YG+LS +EEL + R+EP E K++ +DF
Sbjct: 121 IIEFIQNLIEKGYAYVIDGDVYFHVPAFEHYGELSKQSLEELNRH-RIEPDERKRDVKDF 179
Query: 182 ALWKKAKPGEPK----WDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHEN 237
ALWK AK + K +DSPWG GRPGWHIECSVMS+KYLG FDIHGGG DLIFPHHEN
Sbjct: 180 ALWKSAKEADLKAQAVFDSPWGRGRPGWHIECSVMSAKYLGVPFDIHGGGKDLIFPHHEN 239
Query: 238 EIAQSEACFGHEWVRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKH 297
E AQS A FG E V+ W+H F+ +KGEKMSKSLGN V +R++LQRY EV+R F+L H
Sbjct: 240 ERAQSFARFGVEPVKIWVHNDFIRIKGEKMSKSLGNIVRIRDVLQRYEGEVLRYFLLTAH 299
Query: 298 YRSPLDYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREARKKF 357
YRSPLDYTEE L+ AK E L + L I + M A L K+ + + + ++F
Sbjct: 300 YRSPLDYTEEALERAKRAYEYLRSAL--INLDMEIAYLKTFGDRKEGNQVD-VEDYIRRF 356
Query: 358 YDAMDDDFNTAEALKAVFEVSNAINKYILEVDKPKESILRKALEFFKVVSEVFGIFEDYF 417
+AM+ D +T +A+ + E + INK + E+ + L +A FK + V G+FE
Sbjct: 357 EEAMNRDLHTPDAIAVLHEFAGLINKSLYELSLNQAEELYEA---FKRLCGVLGLFEKME 413
Query: 418 KEEKKGEE--EKLIELLVEVRKQLRKEKRFDLADKIREELRKLGIQLEDKGQETVWK 472
+ E EK++E R++ RKE+ F+LAD IR+E K GI+L D + T W+
Sbjct: 414 RVPALSREDAEKVVE-----RERARKERNFELADAIRDEFAKRGIRLIDTPKGTRWR 465
>sp|P43816|SYC_HAEIN CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LIGASE) (CYSRS)
>gi|1073961|pir||C64047 cysteine--tRNA ligase (EC
6.1.1.16) - Haemophilus influenzae (strain Rd KW20)
>gi|1573026|gb|AAC21753.1| (U32693) cysteinyl-tRNA
synthetase (cysS) [Haemophilus influenzae Rd]
Length = 459
Score = 433 bits (1102), Expect = e-120
Identities = 219/472 (46%), Positives = 295/472 (62%), Gaps = 16/472 (3%)
Query: 3 IKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGFTV 62
+K++NTLTR+KE KP+ + +V MYVCG TVYD H+GH RT++ FDVI RYL G+ +
Sbjct: 2 LKIFNTLTREKEIFKPIHENKVGMYVCGVTVYDLCHIGHGRTFVCFDVIARYLRSLGYDL 61
Query: 63 LMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHIDDI 122
V N TD+DDKIIKRA E E +L +R ++ +D +AL V D PR T HI +I
Sbjct: 62 TYVRNITDVDDKIIKRALENKETCDQLVDRMVQEMYKDFDALNVLRPDFEPRATHHIPEI 121
Query: 123 IEFIKKLKEKGYAYEGSDG-VYFEVQKFKDYGKLSGVKIEELRKGARVEPGEGKKNPEDF 181
IE ++KL ++G+AY +G V F+V+ FK+YGKLS +E+L+ GAR+E E KKNP DF
Sbjct: 122 IEIVEKLIKRGHAYVADNGDVMFDVESFKEYGKLSRQDLEQLQAGARIEINEIKKNPMDF 181
Query: 182 ALWKKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIAQ 241
LWK +K EP W SPWG GRPGWHIECS M+ K LGE FDIHGGG+DL+FPHHENEIAQ
Sbjct: 182 VLWKMSKENEPSWASPWGAGRPGWHIECSAMNCKQLGEYFDIHGGGSDLMFPHHENEIAQ 241
Query: 242 SEACFGHEWVRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHYRSP 301
S G ++V YW+H+G +MV EKMSKSLGNF T+R++L Y+ E +R F+L HYRS
Sbjct: 242 SCCAHGGQYVNYWIHSGMIMVDKEKMSKSLGNFFTIRDVLNHYNAEAVRYFLLTAHYRSQ 301
Query: 302 LDYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREARKKFYDAM 361
L+Y+EE L A+ LERLY L + + + ++F A F +AM
Sbjct: 302 LNYSEENLNLAQGALERLYTALRG------TDQSAVAFGGENFVA---------TFREAM 346
Query: 362 DDDFNTAEALKAVFEVSNAINKYILEVDKPKESILRKALEFFKVVSEVFGIFEDYFKEEK 421
DDDFNT AL +FE++ INK E + + + E ++ + E + +
Sbjct: 347 DDDFNTPNALSVLFEMAREINKLKTEDVEKANGLAARLRELGAILGLLQQEPEKFLQAGS 406
Query: 422 KGEEEKLIELLVEVRKQLRKEKRFDLADKIREELRKLGIQLEDKGQETVWKR 473
+E IE L++ R + R K + AD R EL +GI LED T W++
Sbjct: 407 NDDEVAKIEALIKQRNEARTAKDWSAADSARNELTAMGIVLEDGPNGTTWRK 458
>sp|Q9KQZ9|SYC_VIBCH CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LIGASE) (CYSRS)
>gi|11271614|pir||A82150 cysteinyl-tRNA synthetase
VC1848 [imported] - Vibrio cholerae (group O1 strain
N16961) >gi|9656376|gb|AAF94996.1| (AE004260)
cysteinyl-tRNA synthetase [Vibrio cholerae]
Length = 459
Score = 427 bits (1087), Expect = e-118
Identities = 217/473 (45%), Positives = 300/473 (62%), Gaps = 18/473 (3%)
Query: 3 IKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGFTV 62
+K+YN+LTR+KEE KP+ G+V MYVCG T+YD H+GH RT+++FDV+ RYL + G+ +
Sbjct: 2 LKIYNSLTRQKEEFKPIVAGKVGMYVCGVTIYDLCHIGHGRTFVSFDVVARYLRYLGYDL 61
Query: 63 LMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHIDDI 122
V N TDIDDKIIKRA E E L ER I+ D +AL +K D+ PR T +I++I
Sbjct: 62 TFVRNITDIDDKIIKRAAENAETCESLTERLIQEMYADFDALNIKRPDVEPRATAYIEEI 121
Query: 123 IEFIKKLKEKGYAYEGSDG-VYFEVQKFKDYGKLSGVKIEELRKGARVEPGEGKKNPEDF 181
I +++L E+G+AY +G V FEV ++ +YGKLS +++L+ GARV+ K++P DF
Sbjct: 122 IALVERLIERGFAYVADNGDVMFEVSQYSEYGKLSKQDLDQLQAGARVDIEAAKRSPLDF 181
Query: 182 ALWKKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIAQ 241
LWK +KPGEP W+SPWG GRPGWHIECS M+S LG FDIHGGG+DL FPHHENEIAQ
Sbjct: 182 VLWKMSKPGEPTWESPWGSGRPGWHIECSAMNSSILGTHFDIHGGGSDLQFPHHENEIAQ 241
Query: 242 SEACFGHEWVRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHYRSP 301
S ++V W+H+G VMV EKMSKSLGNF T+R++L Y E +R F++ HYRS
Sbjct: 242 SCCAHDTQYVNTWMHSGMVMVDKEKMSKSLGNFFTIRDVLGHYDAETVRYFLMSGHYRSQ 301
Query: 302 LDYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREARKKFYDAM 361
L+Y+EE L A+ +LERLYN L + ++ A E +F AM
Sbjct: 302 LNYSEENLNQARASLERLYNALRGLDRSVPAA---------------GGEEYVTRFTAAM 346
Query: 362 DDDFNTAEALKAVFEVSNAINKYILEVDKPKESILRKAL-EFFKVVSEVFGIFEDYFKEE 420
+DDFNT EA +F+++ IN+ E D S L + E V+ ++ E +F+
Sbjct: 347 NDDFNTPEAYSVLFDMAREINRLKSE-DMTNASALGSLMRELADVIGILYQEPEAFFQGS 405
Query: 421 KKGEEEKLIELLVEVRKQLRKEKRFDLADKIREELRKLGIQLEDKGQETVWKR 473
+ E+ IE L+++R R K + AD R++L ++GI LED T W+R
Sbjct: 406 AEDEDAAQIEALIKLRNDSRATKDWANADLARDKLNEMGIVLEDGPNGTTWRR 458
>pir||H82030 cysteine--tRNA ligase (EC 6.1.1.16) NMA0347 [imported] - Neisseria
meningitidis (group A strain Z2491)
>gi|7379102|emb|CAB83651.1| (AL162752) cysteinyl-tRNA
synthetase [Neisseria meningitidis Z2491]
Length = 699
Score = 424 bits (1078), Expect = e-117
Identities = 228/492 (46%), Positives = 297/492 (60%), Gaps = 46/492 (9%)
Query: 5 VYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGFTVLM 64
+YNTLTR+KE P+ VRMYVCG TVYDY HLGHAR + FD+I R+L G+ +
Sbjct: 230 IYNTLTRQKEPFAPIDPKNVRMYVCGMTVYDYCHLGHARVMVVFDMIARWLRECGYPLTY 289
Query: 65 VMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHIDDIIE 124
V N TDIDDKII RA E GE G+L RFI+ ED +AL V DI P+ TE+I +I
Sbjct: 290 VRNITDIDDKIIARAAENGETIGELTARFIQAMHEDADALGVLRPDIEPKATENIPQMIA 349
Query: 125 FIKKLKEKGYAYEGSDG-VYFEVQKFKDYGKLSGVKIEELRKGARVEPGEGKKNPEDFAL 183
I+ L + G AY ++G VY+ V++F YG+LSG +++LR G RVE K++P DF L
Sbjct: 350 MIETLIQNGKAYPAANGDVYYAVREFSAYGQLSGKSLDDLRAGERVEVDGFKRDPLDFVL 409
Query: 184 WKKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIAQSE 243
WK AK GEP W+SPWG GRPGWHIECS MS G +FDIHGGG DL FPHHENEIAQS
Sbjct: 410 WKAAKAGEPAWESPWGNGRPGWHIECSAMSENLFGNTFDIHGGGADLQFPHHENEIAQSV 469
Query: 244 ACFGH----------------EWVRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPE 287
GH V+YWLH GF+ V GEKMSKSLGNF T+RE+L++Y PE
Sbjct: 470 GATGHTCGHHHAQTHHGQSIASHVKYWLHNGFIRVDGEKMSKSLGNFFTIREVLKQYDPE 529
Query: 288 VIRLFVLQKHYRSPLDYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAY 347
V+R F+L+ HYRSPL+Y++ L AK L RLY TL+N A +F+
Sbjct: 530 VVRFFILRAHYRSPLNYSDAHLDDAKGALTRLYTTLKNTPAA-------------EFDLS 576
Query: 348 EAIREARKKFYDAMDDDFNTAEALKAVFEVSNAINKYILEVDKPKESILRKALEFFKVVS 407
E + + ++FY AM+DDF T EA+ +FE++ EV+K ++ L L K +
Sbjct: 577 ENVNDYTRRFYAAMNDDFGTVEAVAVLFELAG-------EVNKTNDAQLAGCL---KALG 626
Query: 408 EVFGIFEDYFKE------EKKGEEEKLIELLVEVRKQLRKEKRFDLADKIREELRKLGIQ 461
+ G+ + E G + IE L+ RKQ R +K + +D+IR+ L + I
Sbjct: 627 GIIGLLQRDPTEFLQGGAASDGLSNEEIEDLIARRKQARADKNWAESDRIRDLLNEHKII 686
Query: 462 LEDKGQETVWKR 473
LED T W+R
Sbjct: 687 LEDNAGGTTWRR 698
>gb|AAD20662.1| (AC006593) putative cysteinyl-tRNA synthetase [Arabidopsis
thaliana]
Length = 563
Score = 424 bits (1078), Expect = e-117
Identities = 218/483 (45%), Positives = 297/483 (61%), Gaps = 16/483 (3%)
Query: 5 VYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGFTVLM 64
++NT++RKKE KP +G+V MYVCG T YD H+GHAR Y+ FDV+ RYL+H G+ V
Sbjct: 67 LHNTMSRKKELFKPKVEGKVGMYVCGVTAYDLSHIGHARVYVTFDVLLRYLKHLGYEVSY 126
Query: 65 VMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHIDDIIE 124
V NFTD+DDKII RA+E EDP L+ RF + F DM L+ + PRV++HI II+
Sbjct: 127 VRNFTDVDDKIIARAKELEEDPISLSRRFCEEFNRDMEQLQCLDPSVQPRVSDHIPQIID 186
Query: 125 FIKKLKEKGYAYEGSDGVYFEVQKFKDYGKLSGVKIEELRKGARVEPGEGKKNPEDFALW 184
IK++ + GYAY+ +YF V KF YGKLSG K+E+ R G RV KK+P DFALW
Sbjct: 187 LIKQILDNGYAYKVDGDIYFSVDKFPTYGKLSGRKLEDNRAGERVAVDTRKKHPADFALW 246
Query: 185 KKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIAQSEA 244
K AK GEP W+SPWG GRPGWHIECS MS+ YLG SFDIHGGG DL+FPHHENEIAQS A
Sbjct: 247 KAAKEGEPFWESPWGRGRPGWHIECSAMSAAYLGYSFDIHGGGMDLVFPHHENEIAQSCA 306
Query: 245 CFGHEWVRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHYRSPLDY 304
+ YW+H GFV V EKMSKSLGNF T+R+++ Y P +RLF++ HYRSP++Y
Sbjct: 307 ACDSSNISYWIHNGFVTVDSEKMSKSLGNFFTIRQVIDLYHPLALRLFLMGTHYRSPINY 366
Query: 305 TEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREARKKFYDAMDDD 364
++ L+ A + +Y TL + A+ + +++ + +I R +F +M DD
Sbjct: 367 SDFLLESASERIFYIYQTLHDCESALGEKDSTFENGSVPSDTLTSINTFRTEFVASMSDD 426
Query: 365 FNTAEALKAVFEVSNAINKYILEVDKPKESILR----KALE-FFKVVSEVFGIFEDYFKE 419
T L A+ E IN ++ K K+ R KALE + V + G+ + E
Sbjct: 427 LLTPVTLAAMSEPLKTIND-LIHTRKGKKQARREESLKALETTIRDVLTILGLMPTSYSE 485
Query: 420 ----------EKKGEEEKLIELLVEVRKQLRKEKRFDLADKIREELRKLGIQLEDKGQET 469
++ G +E+ + V+ R RK K ++ +D IR++L K+GI L D + T
Sbjct: 486 VLEQLKEKALKRAGLKEEDVLQRVQERTDARKNKEYERSDAIRKDLAKVGIALMDSPEGT 545
Query: 470 VWK 472
W+
Sbjct: 546 TWR 548
>sp|P21888|SYC_ECOLI CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LIGASE) (CYSRS)
>gi|68549|pir||YYEC cysteine--tRNA ligase (EC 6.1.1.16)
- Escherichia coli >gi|41206|emb|CAA41983.1| (X59293)
cysteinyl-tRNA synthetase [Escherichia coli]
>gi|145692|gb|AAA23658.1| (M59381) transfer RNA-Cys
synthetase [Escherichia coli] >gi|1773207|gb|AAB40279.1|
(U82664) cysteinyl-tRNA synthetase [Escherichia coli]
>gi|1786737|gb|AAC73628.1| (AE000158) cysteine tRNA
synthetase [Escherichia coli K12]
>gi|227964|prf||1714234A Cys-tRNA synthetase
[Escherichia coli]
Length = 461
Score = 423 bits (1075), Expect = e-117
Identities = 221/479 (46%), Positives = 299/479 (62%), Gaps = 28/479 (5%)
Query: 3 IKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGFTV 62
+K++NTLTR+KEE KP+ GEV MYVCG TVYD H+GH RT++AFDV+ RYL G+ +
Sbjct: 2 LKIFNTLTRQKEEFKPIHAGEVGMYVCGITVYDLCHIGHGRTFVAFDVVARYLRFLGYKL 61
Query: 63 LMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHIDDI 122
V N TDIDDKIIKRA E GE + +R I +D +AL + D+ PR T HI +I
Sbjct: 62 KYVRNITDIDDKIIKRANENGESFVAMVDRMIAEMHKDFDALNILRPDMEPRATHHIAEI 121
Query: 123 IEFIKKLKEKGYAYEGSDG-VYFEVQKFKDYGKLSGVKIEELRKGARVEPGEGKKNPEDF 181
IE ++L KG+AY +G V F+V YG LS +++L+ GARV+ + K+NP DF
Sbjct: 122 IELTEQLIAKGHAYVADNGDVMFDVPTDPTYGVLSRQDLDQLQAGARVDVVDDKRNPMDF 181
Query: 182 ALWKKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIAQ 241
LWK +K GEP W SPWG GRPGWHIECS M+ K LG FDIHGGG+DL+FPHHENEIAQ
Sbjct: 182 VLWKMSKEGEPSWPSPWGAGRPGWHIECSAMNCKQLGNHFDIHGGGSDLMFPHHENEIAQ 241
Query: 242 SEACFGHEWVRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHYRSP 301
S ++V YW+H+G VMV EKMSKSLGNF TVR++L+ Y E +R F++ HYRS
Sbjct: 242 STCAHDGQYVNYWMHSGMVMVDREKMSKSLGNFFTVRDVLKYYDAETVRYFLMSGHYRSQ 301
Query: 302 LDYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREARKKFYDAM 361
L+Y+EE L+ A+ LERLY L + A EA+EA +F +AM
Sbjct: 302 LNYSEENLKQARAALERLYTALRGTDKTVAPA---------GGEAFEA------RFIEAM 346
Query: 362 DDDFNTAEALKAVFEVSNAINKYILEVDKPKESILRKAL-EFFKVVSEVFGIFED----Y 416
DDDFNT EA +F+++ +N+ K ++ A+ + +S V G+ E +
Sbjct: 347 DDDFNTPEAYSVLFDMAREVNRL-----KAEDMAAANAMASHLRKLSAVLGLLEQEPEAF 401
Query: 417 FKEEKKGEEEKL--IELLVEVRKQLRKEKRFDLADKIREELRKLGIQLEDKGQETVWKR 473
+ + ++ ++ IE L++ R RK K + AD R+ L ++GI LED Q T W+R
Sbjct: 402 LQSGAQADDSEVAEIEALIQQRLDARKAKDWAAADAARDRLNEMGIVLEDGPQGTTWRR 460
>emb|CAA39691.1| (X56234) cysteine-tRNA ligase [Escherichia coli]
Length = 461
Score = 421 bits (1072), Expect = e-117
Identities = 220/479 (45%), Positives = 299/479 (61%), Gaps = 28/479 (5%)
Query: 3 IKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGFTV 62
+K++NTLTR+KEE KP+ GEV MYVCG TVYD H+GH RT++AFDV+ RYL G+ +
Sbjct: 2 LKIFNTLTRQKEEFKPIHAGEVGMYVCGITVYDLCHIGHGRTFVAFDVVARYLRFLGYKL 61
Query: 63 LMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHIDDI 122
V N TDIDDKIIKRA E GE + +R I +D +AL + D+ PR T HI +I
Sbjct: 62 KYVRNITDIDDKIIKRANENGESFVAMVDRMIAEMHKDFDALNILRPDMEPRATHHIAEI 121
Query: 123 IEFIKKLKEKGYAYEGSDG-VYFEVQKFKDYGKLSGVKIEELRKGARVEPGEGKKNPEDF 181
IE ++L KG+AY +G V F+V YG LS +++L+ GARV+ + K+NP DF
Sbjct: 122 IELTEQLIAKGHAYVADNGDVMFDVPTDPTYGVLSRQDLDQLQAGARVDVVDDKRNPMDF 181
Query: 182 ALWKKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIAQ 241
LWK +K GEP W SPWG GRPGWHIECS M+ K LG FDIHGGG+DL+FPHHENEIAQ
Sbjct: 182 VLWKMSKEGEPSWPSPWGAGRPGWHIECSAMNCKQLGNHFDIHGGGSDLMFPHHENEIAQ 241
Query: 242 SEACFGHEWVRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHYRSP 301
S ++V YW+H+G VMV EKMSKSLGNF TVR++L+ Y E +R F++ HYRS
Sbjct: 242 STCAHDGQYVNYWMHSGMVMVDREKMSKSLGNFFTVRDVLKYYDAETVRYFLMSGHYRSQ 301
Query: 302 LDYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREARKKFYDAM 361
L+Y+EE L+ A+ +ERLY L + A EA+EA +F +AM
Sbjct: 302 LNYSEENLKQARAAVERLYTALRGTDKTVAPA---------GGEAFEA------RFIEAM 346
Query: 362 DDDFNTAEALKAVFEVSNAINKYILEVDKPKESILRKAL-EFFKVVSEVFGIFED----Y 416
DDDFNT EA +F+++ +N+ K ++ A+ + +S V G+ E +
Sbjct: 347 DDDFNTPEAYSVLFDMAREVNRL-----KAEDMAAANAMASHLRKLSAVLGLLEQEPEAF 401
Query: 417 FKEEKKGEEEKL--IELLVEVRKQLRKEKRFDLADKIREELRKLGIQLEDKGQETVWKR 473
+ + ++ ++ IE L++ R RK K + AD R+ L ++GI LED Q T W+R
Sbjct: 402 LQSGAQADDSEVAEIEALIQQRLDARKAKDWAAADAARDRLNEMGIVLEDGPQGTTWRR 460
>pir||B81007 cysteinyl-tRNA synthetase NMB2083 [imported] - Neisseria
meningitidis (group B strain MD58)
>gi|7227346|gb|AAF42401.1| (AE002558) cysteinyl-tRNA
synthetase [Neisseria meningitidis MC58]
Length = 473
Score = 418 bits (1064), Expect = e-116
Identities = 229/492 (46%), Positives = 297/492 (59%), Gaps = 46/492 (9%)
Query: 5 VYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGFTVLM 64
+YNTLTR+KE P+ VRMYVCG TVYDY HLGHAR + FD+I R+L G+ +
Sbjct: 4 IYNTLTRQKEPFSPIDPENVRMYVCGMTVYDYCHLGHARVMVVFDMIARWLRECGYPLTY 63
Query: 65 VMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHIDDIIE 124
V N TDIDDKII RA E GE GKL RFI+ ED +AL V DI P+ TE+I +I
Sbjct: 64 VRNITDIDDKIIARAAENGETIGKLTARFIQAMHEDADALGVLRPDIEPKATENIPQMIA 123
Query: 125 FIKKLKEKGYAYEGSDG-VYFEVQKFKDYGKLSGVKIEELRKGARVEPGEGKKNPEDFAL 183
I+ L + G AY ++G VY+ V++F YG+LSG +++LR G RVE K++P DF L
Sbjct: 124 MIETLIQNGKAYPAANGDVYYAVREFAAYGQLSGKSLDDLRAGERVEVDGFKRDPLDFVL 183
Query: 184 WKKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIAQSE 243
WK AK GEP W+SPWG GRPGWHIECS MS G++FDIHGGG DL FPHHENEIAQS
Sbjct: 184 WKAAKAGEPAWESPWGNGRPGWHIECSAMSENLFGDTFDIHGGGADLQFPHHENEIAQSV 243
Query: 244 ACFGH----------------EWVRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPE 287
GH V+YWLH GF+ V GEKMSKSLGNF T+RE+L++Y PE
Sbjct: 244 GATGHTCGHHHAQTHHGQSIASHVKYWLHNGFIRVDGEKMSKSLGNFFTIREVLKQYDPE 303
Query: 288 VIRLFVLQKHYRSPLDYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAY 347
V+R F+L+ HYRSPL+Y++ L AK L RLY TL+N A D
Sbjct: 304 VVRFFILRAHYRSPLNYSDAHLDDAKGALTRLYTTLKNTPPA-------------DPMPS 350
Query: 348 EAIREARKKFYDAMDDDFNTAEALKAVFEVSNAINKYILEVDKPKESILRKALEFFKVVS 407
EA + ++FY AM+DDF+T +A+ +FE++ EV+K ++ L L K +
Sbjct: 351 EAGDDYTRRFYVAMNDDFDTVKAVAVLFELAG-------EVNKTNDAQLAGRL---KALG 400
Query: 408 EVFGIFEDYFKE------EKKGEEEKLIELLVEVRKQLRKEKRFDLADKIREELRKLGIQ 461
+ G+ + E G + IE L+ RKQ R +K + +D+IR+ L + I
Sbjct: 401 GIIGLLQRDPTEFLQGGAASDGLSNEEIEDLIARRKQARADKNWAESDRIRDLLNEHKII 460
Query: 462 LEDKGQETVWKR 473
LED T W+R
Sbjct: 461 LEDNAGGTTWRR 472
>emb|CAC12272.1| (AL445066) probable cysteinyl-tRNA synthetase [Thermoplasma
acidophilum]
Length = 452
Score = 418 bits (1064), Expect = e-116
Identities = 209/470 (44%), Positives = 299/470 (63%), Gaps = 20/470 (4%)
Query: 3 IKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGFTV 62
++ YNTLTR +E K + G + M+VCGPTV D+ H+GHARTYI FD + + L + G++V
Sbjct: 1 MRFYNTLTRDVDEFKEMNSGRINMFVCGPTVQDHFHIGHARTYIFFDAVAKLLRNLGYSV 60
Query: 63 LMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHIDDI 122
+ N TDIDDKII +A+E P +A+ +++ FLEDM+ALKV + + + T +I++I
Sbjct: 61 FYLQNITDIDDKIINKAREMNIQPQDVADMYLREFLEDMSALKVTSVNYFAKSTLYINEI 120
Query: 123 IEFIKKLKEKGYAYEGSDGVYFEVQKFKDYGKLSGVKIEELRKGARVEPGEGKKNPEDFA 182
I I +L EKGYAYE SDGVYFEV KF DYG+LS ++++ G RV E K+NPEDF
Sbjct: 121 ISQISRLIEKGYAYETSDGVYFEVSKFADYGQLSNQSLDQIIHGYRVAVNENKRNPEDFV 180
Query: 183 LWKKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIAQS 242
LWKK KPGEP WDSPWG GRPGWHIE + ++ Y G +DIHGGG+DLIFPHHE EIAQ
Sbjct: 181 LWKKRKPGEPYWDSPWGPGRPGWHIEDTAITETYFGPEYDIHGGGSDLIFPHHEAEIAQM 240
Query: 243 EACFGHEWV-RYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHYRSP 301
A G +++ YW+HTG + V EKMSKSL NFVT+RE+L+ Y PE +R +L +YR+
Sbjct: 241 RAISGRKYLSHYWIHTGMINVNNEKMSKSLKNFVTIREVLKEYRPEDLRYALLNANYRTQ 300
Query: 302 LDYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREARKKFYDAM 361
LD+++ L+ ++ +E L +T + A N++LS S K+ D
Sbjct: 301 LDFSKGLLEESRKQVEYLNSTFRKLVNASGNSDLSADPS-----------AVIKRMVDEA 349
Query: 362 DDDFNTAEALKAVFEVSNAINKYILEVDKPKESILRKALEFFKVVSEVFGIFEDYFKEEK 421
+DF+ + + + + +NK I + +P +KA++ F+ V GI +
Sbjct: 350 TNDFDFRSVFRDLIDFAGDLNKNIESISRP---AAQKAIDVFRWVDSFAGIL-----LPE 401
Query: 422 KGEEEKLIELLVEVRKQLRKEKRFDLADKIREELRKLGIQLEDKGQETVW 471
+I+ L+++RK LR E++F AD+IR+ L K GI +ED+G ET+W
Sbjct: 402 TARLSGIIDDLLDLRKNLRTERKFQEADRIRDLLLKNGIHVEDRGDETIW 451
>gb|AAF06821.1|AF065890_2 (AF065890) cysteinyl-tRNA synthetase [Thermoproteus tenax]
Length = 484
Score = 416 bits (1057), Expect = e-115
Identities = 214/478 (44%), Positives = 302/478 (62%), Gaps = 18/478 (3%)
Query: 3 IKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGFTV 62
+++YNT +++ E L G R YVCG T YD H+GH R Y+ FD++RRYLEH G V
Sbjct: 6 LRIYNTASKRVEPFSVLTPGVARGYVCGITPYDSVHVGHGRVYVFFDILRRYLEHLGLEV 65
Query: 63 LMVMNFTDIDDKIIKRAQET-GEDP----GKLAERFIKVFLEDMNALKVKPADIYPRVTE 117
+V+NFTD+DDKII RA+E G D ++ ER+I+ + + M L VKPA YPRVTE
Sbjct: 66 KLVINFTDVDDKIINRAREEFGADAVSRWREVPERYIREYFDVMERLYVKPAYAYPRVTE 125
Query: 118 HIDDIIEFIKKLKEKGYAYEGSDG-VYFEVQKFKDYGKLSGVKIEELRKGARVEPGEGKK 176
++ D++E+I+ L ++GYAY DG VYFEV K YG+ SG +IEEL GARVEP GK+
Sbjct: 126 YVGDMLEWIRALVDRGYAYVAPDGSVYFEVGKVPRYGEFSGQRIEELVAGARVEPEPGKR 185
Query: 177 NPEDFALWKKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHE 236
NP DFALWK PGEP W+SPW GRPGWH+EC VMS+K+LG FD HGGG DLIFPHHE
Sbjct: 186 NPLDFALWKSWSPGEPWWNSPWCPGRPGWHLECVVMSTKHLGVPFDFHGGGADLIFPHHE 245
Query: 237 NEIAQSEACFGHEW-VRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQ 295
NEIA + A G ++ RYW+H G++ V GEKMSKSLGN +T++E+L +Y E +RL
Sbjct: 246 NEIAIARAMHGVDYFARYWIHVGYLTVGGEKMSKSLGNIITLKEVLSKYDGEALRLAYAM 305
Query: 296 KHYRSPLDYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAY-EAIREAR 354
HYR P++++ + L A L +Y + + A+ +A E+D E R
Sbjct: 306 SHYRKPMEFSYDLLDRAVELLGTMYTAYDELSQAVADA------GERDVAPLAEEASSYR 359
Query: 355 KKFYDAMDDDFNTAEALKAVFEVSN-AINKYILEVDKPKESILRKALEFFKVVSEVFGIF 413
+KF +A+ DD +T EA +A+++++ I+K + VDK L + +++V G+
Sbjct: 360 RKFEEALADDMSTNEAARALYDMARFIISKVLYSVDKISRETALGILRDYAEMADVLGLL 419
Query: 414 EDYFKEEKKGEEEKLIELLVEVRKQLRKEKRFDLADKIREELRKLGIQLEDKGQETVW 471
K E E + + +VE R +LR E+++ LAD +R+ R LG+++ D G T +
Sbjct: 420 N---KREVPRELAEAVRAIVEARSRLRSERQYALADMLRDRARALGVEMHDMGPRTFY 474
>sp|P74330|SYC_SYNY3 CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LIGASE) (CYSRS)
>gi|7428477|pir||S76165 cysteine--tRNA ligase (EC
6.1.1.16) - Synechocystis sp. (strain PCC 6803)
>gi|1653511|dbj|BAA18424.1| (D90914) cysteinyl-tRNA
synthetase [Synechocystis sp.]
Length = 483
Score = 413 bits (1051), Expect = e-114
Identities = 227/487 (46%), Positives = 295/487 (59%), Gaps = 18/487 (3%)
Query: 1 MGIKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGF 60
M +++Y++LTR K+ L+PL G V MY CG TVYDY HLGHART I +D++RRYL+ G+
Sbjct: 1 MTLRLYDSLTRAKQPLQPLHPGLVTMYCCGITVYDYCHLGHARTCITWDLVRRYLQWSGY 60
Query: 61 TVLMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHID 120
V V NFTDIDDKI+KRA + ++E+FI + EDM AL V+PAD+YPR T +D
Sbjct: 61 EVRYVQNFTDIDDKILKRAVDESSTMEAVSEKFIAAYFEDMEALGVQPADLYPRATHTLD 120
Query: 121 DIIEFIKKLKEKGYAYEGSDGVYFEVQKFKDYGKLSGVKIEELRKGAR-----VEP-GEG 174
I I +L+ KGYAY VY+ V+ F YGKLSG ++E+L+ GA +P G
Sbjct: 121 GIKRLIAELEAKGYAYPSGGDVYYSVRNFDGYGKLSGRRLEDLQAGASGRVTVADPDGAQ 180
Query: 175 KKNPEDFALWKKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPH 234
K++P DFALWK AKPGEP W+SPWG+GRPGWHIECS M ++LGE+ D+H GGNDLIFPH
Sbjct: 181 KQDPFDFALWKSAKPGEPAWESPWGKGRPGWHIECSAMVREFLGETIDLHVGGNDLIFPH 240
Query: 235 HENEIAQSEACFGHEWVRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRLFVL 294
HENEIAQSEA G +YWLH G V V GEKMSKSLGNF T+R LL+ P IRL VL
Sbjct: 241 HENEIAQSEAVTGQPLAQYWLHNGMVKVDGEKMSKSLGNFTTIRALLKTVDPMAIRLLVL 300
Query: 295 QKHYRSPLDYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREAR 354
Q HYR PLD+TE + A N L L+ + + W +
Sbjct: 301 QGHYRKPLDFTETAIAAATNGWHTLREGLQ----FGYDYGGDFGWELAFTPLGPDANQWT 356
Query: 355 KKFYDAMDDDFNTAEALKAVFEVSNAI----NKYILEVDKPKE-SILRKALEFFKVVSEV 409
F +A+DDDFN A L +FE++ + NK E P + +L+ ++E+
Sbjct: 357 VAFQEAVDDDFNFAGGLAVMFELAKHLRSEGNKLKFEGSTPADLDLLQTQWITLVSLAEI 416
Query: 410 FG--IFEDYFKEEKKGEEEKLIELLVEVRKQLRKEKRFDLADKIREELRKLGIQLEDK-G 466
G I + G + IE LV R Q RK+K + D++R+ L++ GI L DK G
Sbjct: 417 LGLSINPESQSSNDNGLTDGDIEQLVAQRTQARKDKNWAEGDRLRDVLQEAGITLVDKPG 476
Query: 467 QETVWKR 473
T W R
Sbjct: 477 GLTEWFR 483
>dbj|BAB08639.1| (AB009048) cysteine-tRNA ligase [Arabidopsis thaliana]
Length = 500
Score = 395 bits (1003), Expect = e-109
Identities = 220/493 (44%), Positives = 293/493 (58%), Gaps = 30/493 (6%)
Query: 1 MGIKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGF 60
M +K+YNT+T++KE L P+ G++ +YVCG T YD+ H+GHAR ++FDV+ RYL+H +
Sbjct: 6 MELKLYNTMTQQKEVLIPITPGKIGLYVCGITAYDFSHIGHARAAVSFDVLYRYLKHLDY 65
Query: 61 TVLMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHID 120
V V NFTD+DDKII RA + GEDP L+ RF +L DM AL+ P PRV+EH+D
Sbjct: 66 DVTFVRNFTDVDDKIIDRANKNGEDPLDLSNRFCDEYLVDMGALQCLPPTHQPRVSEHMD 125
Query: 121 DIIEFIKKLKEKGYAYEGSDGVYFEVQKFKDYGKLSGVKIEELRKGARVEPGEGKKNPED 180
+II+ I+K+ EK Y V+F V K +YGKLSG +E R G RV K+NP D
Sbjct: 126 NIIKMIEKIIEKDCGYVVEGDVFFSVDKSPNYGKLSGQLLEHTRAGERVAVDSRKRNPAD 185
Query: 181 FALWKKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIA 240
FALWK AKP EP W+SPWG GRPGWHIECS MS YL FDIHGGG DL FPHHENEIA
Sbjct: 186 FALWKAAKPDEPSWESPWGPGRPGWHIECSAMSVHYLSPKFDIHGGGADLKFPHHENEIA 245
Query: 241 QSEACFGHEWVRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHYRS 300
Q+ A V YWLH G V + EKM+KS NF T+RE+ Y P +R F++ YRS
Sbjct: 246 QTCAACEDSGVNYWLHNGHVTINNEKMAKSKHNFKTIREITASYHPLALRHFLMSAQYRS 305
Query: 301 PLDYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREARKKFYDA 360
PL +T L+ ++ E LY L + A+ +E K SE+ E + I++ + +F
Sbjct: 306 PLSFTASQLE---SSSEALY-CLSPYQDAL--SEDGGK-SEQTAEGKDIIKKLKTEFESK 358
Query: 361 MDDDFNTAEALKAVFE-----VSNAINKYILEVDKPKESILRKALEFFKVVSEVFGI--- 412
M DD NTA L ++ ++ +++K K + S+L +E K EV +
Sbjct: 359 MLDDLNTAHILTGAYQDALKFINASLSKLKKMQKKQRMSMLVSLVEIEKAAREVLDVLGL 418
Query: 413 -----FEDYFKEEKK--------GEEEKLIELLVEVRKQLRKEKRFDLADKIREELRKLG 459
+ + KE K GEE I L+E R RK K F +D+IRE+L + G
Sbjct: 419 LTTLSYAEILKEMKLKTLIRAEIGEEG--ISQLIEERITARKNKDFAKSDEIREKLTRKG 476
Query: 460 IQLEDKGQETVWK 472
I L D G+ETVW+
Sbjct: 477 IALMDIGKETVWR 489
>gb|AAF18751.1|AF164201_1 (AF164201) cysteinyl-tRNA synthetase [Methanosarcina barkeri]
Length = 471
Score = 385 bits (979), Expect = e-106
Identities = 205/468 (43%), Positives = 292/468 (61%), Gaps = 15/468 (3%)
Query: 3 IKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGFTV 62
++VYNTLTRKKE KPL++GEV +Y CGPTVY+ PH+G+ RT++ D I R LE+ G+ V
Sbjct: 2 LQVYNTLTRKKEVFKPLKEGEVSIYACGPTVYNMPHIGNYRTFLMADNIVRSLEYLGYKV 61
Query: 63 LMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHIDDI 122
+VMN TDIDDK I+ ++ G +++ F + ++ L +K A YPR TE+ID +
Sbjct: 62 KLVMNITDIDDKTIRDSKAAGMSLKDFTDKYTAEFFKGLDMLNIKRASAYPRATENIDSM 121
Query: 123 IEFIKKLKEKGYAYEGSDGVYFEVQKFKDYGKLSGVKIEELRKGARVEPGE-GKKNPEDF 181
IE +KL +KG AYE VY+ + F DYGKLS + + + GA V+ E K NP DF
Sbjct: 122 IELTQKLIDKGMAYEKGGSVYYRISSFPDYGKLSKLDFDSIIIGASVDVDEYDKDNPRDF 181
Query: 182 ALWKKAKPGEPK----WDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHEN 237
AL K + P E + ++SPWG+ RPGWHIECSVM+ G + D+H GG DLIFPHHEN
Sbjct: 182 ALLKTSTPEEIERGIYYESPWGKIRPGWHIECSVMAMNCFGPTLDMHLGGVDLIFPHHEN 241
Query: 238 EIAQSEACFGHEWVRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKH 297
EIAQSE G + YW+H ++V+GEKMSKS GN T+ E++ +Y EV+R L H
Sbjct: 242 EIAQSEGATGKPFACYWIHGEHLIVEGEKMSKSKGNVFTLPEIVGKYGGEVVRFMFLSVH 301
Query: 298 YRSPLDYTEEGLQHAKNNLERLYNTLENIRIAMRNAE-LSYKWSEKDFEAYEAIREARKK 356
YR LDY++ ++AKNN RL TLEN+ ++ +AE Y E E + + E +
Sbjct: 302 YRKKLDYSDAFAENAKNNYLRLKETLENLEFSLESAENTDYPGDE---EVLKILPELETQ 358
Query: 357 FYDAMDDDFNTAEALKAVFEVSNAINKYILEVDKPKESILRKALEFFKVVSEVFGIFEDY 416
F +A++DDFN +AL E+S NKY LE +K + +L K ++ S+ G+F +
Sbjct: 359 FREALEDDFNIPKALTVFKELSRTANKY-LESEKNRH-VLEKLYSLYRQFSDTLGLFSES 416
Query: 417 FKEEKKGEEEKLIELLVEVRKQLRKEKRFDLADKIREELRKLGIQLED 464
K+E E + LVE R+ RK+K + ++D IRE+++ LG ++D
Sbjct: 417 GKKEIPTE----VMRLVEEREAARKKKDWTVSDAIREKIKSLGYIVQD 460
>pir||A75368 cysteinyl-tRNA synthetase - Deinococcus radiodurans (strain R1)
>gi|6459435|gb|AAF11225.1|AE002009_5 (AE002009)
cysteinyl-tRNA synthetase [Deinococcus radiodurans]
Length = 532
Score = 378 bits (961), Expect = e-104
Identities = 201/487 (41%), Positives = 293/487 (59%), Gaps = 22/487 (4%)
Query: 3 IKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGFTV 62
I +Y+T+ R+K P G V MY+CGPTVY HLGHA+ +AFDVIRR L H G+ V
Sbjct: 52 ITLYDTMQRQKVPFVPGTPGYVGMYLCGPTVYSDAHLGHAKKEVAFDVIRRALTHFGYQV 111
Query: 63 LMVMNFTDI----------DDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIY 112
V N TD+ +DK+ RA+ +P ++A+++ F DM+AL V I
Sbjct: 112 RYVSNITDVGHLLNDADEGEDKLQARARLEQLEPMEVADKYFWSFFRDMDALNVLRPSIN 171
Query: 113 PRVTEHIDDIIEFIKKLKEKGYAYEGSDGVYFEVQKFKDYGKLSGVKIEELRKGARVEPG 172
PR T HI + I+ I++L EKG+AYE + VYF+V+ + +YGKLSG K+++ +G R
Sbjct: 172 PRATGHIQEQIKLIEELIEKGHAYESAGSVYFDVRSWPEYGKLSGRKLDDQEEGTREAVR 231
Query: 173 EGKKNPEDFALWKKAKPGE-PKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLI 231
+ K++P DFALWKKA+P +WDSPW G PGWHIECS MS KYLGE FDIHGGG DL
Sbjct: 232 DEKRDPRDFALWKKAEPEHLMRWDSPWSVGFPGWHIECSAMSLKYLGEGFDIHGGGLDLQ 291
Query: 232 FPHHENEIAQSEACFGHEWVRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRL 291
FPHHE EIAQ+EA GH + RYW+H + + GEKMSKS GNF T++++L++Y P V+R
Sbjct: 292 FPHHEAEIAQAEAA-GHHFARYWMHNNMLTIGGEKMSKSKGNFTTIQDILKKYDPMVVRF 350
Query: 292 FVLQKHYRSPLDYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIR 351
++ HYRS + EE A N RL TL I +++A S+ ++ A R
Sbjct: 351 LLVSSHYRSVTEMNEEAFASAANGYRRLSETLHEIERRLKDAPAG---SDTALDSKIAAR 407
Query: 352 EARKKFYDAMDDDFNTAEALKAVFEVSNAINKYILEVDKPKESILRKALEFFKVVSEVFG 411
+F DAM DDFNT +A+ ++F ++ +N + ++++ R + + +V G
Sbjct: 408 VT--EFEDAMRDDFNTPKAVASLFGLTGELNTALNAGPVGRDTLERARDAYRSLGGDVLG 465
Query: 412 IFEDYFKEEKKGEE-----EKLIELLVEVRKQLRKEKRFDLADKIREELRKLGIQLEDKG 466
+F + ++ + L++L+++ R+ R +K++ AD++RE L K GI +ED
Sbjct: 466 LFAETGSAASVAQDDASVIDALMDLVLKARQNYRLQKQYAEADELRETLGKAGITVEDTK 525
Query: 467 QETVWKR 473
WKR
Sbjct: 526 DGARWKR 532
>sp|Q9RTT6|SYC_DEIRA CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LIGASE) (CYSRS)
Length = 498
Score = 378 bits (961), Expect = e-104
Identities = 201/487 (41%), Positives = 293/487 (59%), Gaps = 22/487 (4%)
Query: 3 IKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGFTV 62
I +Y+T+ R+K P G V MY+CGPTVY HLGHA+ +AFDVIRR L H G+ V
Sbjct: 18 ITLYDTMQRQKVPFVPGTPGYVGMYLCGPTVYSDAHLGHAKKEVAFDVIRRALTHFGYQV 77
Query: 63 LMVMNFTDI----------DDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIY 112
V N TD+ +DK+ RA+ +P ++A+++ F DM+AL V I
Sbjct: 78 RYVSNITDVGHLLNDADEGEDKLQARARLEQLEPMEVADKYFWSFFRDMDALNVLRPSIN 137
Query: 113 PRVTEHIDDIIEFIKKLKEKGYAYEGSDGVYFEVQKFKDYGKLSGVKIEELRKGARVEPG 172
PR T HI + I+ I++L EKG+AYE + VYF+V+ + +YGKLSG K+++ +G R
Sbjct: 138 PRATGHIQEQIKLIEELIEKGHAYESAGSVYFDVRSWPEYGKLSGRKLDDQEEGTREAVR 197
Query: 173 EGKKNPEDFALWKKAKPGE-PKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLI 231
+ K++P DFALWKKA+P +WDSPW G PGWHIECS MS KYLGE FDIHGGG DL
Sbjct: 198 DEKRDPRDFALWKKAEPEHLMRWDSPWSVGFPGWHIECSAMSLKYLGEGFDIHGGGLDLQ 257
Query: 232 FPHHENEIAQSEACFGHEWVRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRL 291
FPHHE EIAQ+EA GH + RYW+H + + GEKMSKS GNF T++++L++Y P V+R
Sbjct: 258 FPHHEAEIAQAEAA-GHHFARYWMHNNMLTIGGEKMSKSKGNFTTIQDILKKYDPMVVRF 316
Query: 292 FVLQKHYRSPLDYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIR 351
++ HYRS + EE A N RL TL I +++A S+ ++ A R
Sbjct: 317 LLVSSHYRSVTEMNEEAFASAANGYRRLSETLHEIERRLKDAPAG---SDTALDSKIAAR 373
Query: 352 EARKKFYDAMDDDFNTAEALKAVFEVSNAINKYILEVDKPKESILRKALEFFKVVSEVFG 411
+F DAM DDFNT +A+ ++F ++ +N + ++++ R + + +V G
Sbjct: 374 VT--EFEDAMRDDFNTPKAVASLFGLTGELNTALNAGPVGRDTLERARDAYRSLGGDVLG 431
Query: 412 IFEDYFKEEKKGEE-----EKLIELLVEVRKQLRKEKRFDLADKIREELRKLGIQLEDKG 466
+F + ++ + L++L+++ R+ R +K++ AD++RE L K GI +ED
Sbjct: 432 LFAETGSAASVAQDDASVIDALMDLVLKARQNYRLQKQYAEADELRETLGKAGITVEDTK 491
Query: 467 QETVWKR 473
WKR
Sbjct: 492 DGARWKR 498
>sp|Q9PLE0|SYC_CHLMU CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LIGASE) (CYSRS)
>gi|11271625|pir||A81735 cysteinyl-tRNA synthetase
TC0164 [imported] - Chlamydia muridarum (strain Nigg)
>gi|7190201|gb|AAF39040.1| (AE002283) cysteinyl-tRNA
synthetase [Chlamydia muridarum]
Length = 475
Score = 347 bits (881), Expect = 2e-94
Identities = 191/477 (40%), Positives = 291/477 (60%), Gaps = 25/477 (5%)
Query: 1 MGIKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGF 60
M + +YNTL+R+KE P D V++Y CGPTVYDY H+G+ RTY+ D+++R L G+
Sbjct: 1 MDLFLYNTLSREKERFLPSND-PVKLYTCGPTVYDYAHIGNFRTYVFEDLLKRVLLFLGY 59
Query: 61 TVLMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHID 120
+V VMN TD+DDK + A++ G K + +I F D+ L + AD YP T +I
Sbjct: 60 SVHHVMNITDVDDKTLAGARKKGCSLEKYCQPYINAFFADLETLHILKADAYPHATHYIP 119
Query: 121 DIIEFIKKLKEKGYAYEGSD-GVYFEVQKFKDYGKLSGVKIEELRKGARVEPGE-GKKNP 178
+IE I++L ++G AY G D VYF + +F +YG LS + +EELR+ +R++ E K N
Sbjct: 120 QMIEAIQQLIDQGIAYVGQDQSVYFSISRFPNYGSLSHLNLEELRQSSRIDADEYDKDNL 179
Query: 179 EDFALWKKAKP---GEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHH 235
DF LWK P GE W+SP+G+GRPGWH+ECS+MS LG+S DIH GG D IFPHH
Sbjct: 180 CDFVLWKAYDPNRDGEIFWESPFGKGRPGWHLECSIMSMALLGQSLDIHAGGVDNIFPHH 239
Query: 236 ENEIAQSEACFGHEWVRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQR-YSPEVIRLFVL 294
ENEIAQSE+ +VRYWLH+ ++V G+KMSKSLGNF T+R+LLQ+ +S E +R +L
Sbjct: 240 ENEIAQSESLSRKPFVRYWLHSHHLLVDGKKMSKSLGNFFTLRDLLQQGFSGEEVRYLLL 299
Query: 295 QKHYRSPLDYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREAR 354
Q HYR+ L++T+EGLQ A+ +L+RL + + + ++ + E A +
Sbjct: 300 QGHYRTQLNFTQEGLQAARQSLKRLRDFISRLEDPFYPDDIIHP------EVGSACQNFL 353
Query: 355 KKFYDAMDDDFNTAEALKAVFE----VSNAINKYILEVDKPKESILRKA---LEFFKVVS 407
+ F ++ +D N + AL ++F+ ++ I++ ++ + E + A L + +
Sbjct: 354 EAFVTSITNDLNISSALASLFDFIRKINGMIDRQSIQEETSSEFSKQDAQHILSLLRQID 413
Query: 408 EVFGIFEDYFKEEKKGEEEKLIELLVEVRKQLRKEKRFDLADKIREELRKLGIQLED 464
+V G+ F + E+ + LLV+ R+ RK K + AD++R+E+ G +ED
Sbjct: 414 QVLGVLP--FSQADIPED---VLLLVKEREAARKVKNWKEADRLRDEIISRGFAIED 465
>emb|CAB77329.1| (AL160331) putative cysteinyl-tRNA synthetase [Streptomyces
coelicolor A3(2)]
Length = 613
Score = 344 bits (873), Expect = 1e-93
Identities = 185/475 (38%), Positives = 272/475 (56%), Gaps = 22/475 (4%)
Query: 3 IKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGFTV 62
I++Y+T R+ + PL G V +Y+CG TV PH+GH R+ + FD++RR+ +RG+ V
Sbjct: 150 IRLYDTSARQIRDFAPLTPGCVSIYLCGATVQAAPHIGHIRSGLNFDIMRRWFAYRGYDV 209
Query: 63 LMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHIDDI 122
V N TDIDDKII++A E + + F + AL P PR T HI ++
Sbjct: 210 TFVRNVTDIDDKIIRKAAEQNRPWWSIGYENERAFNDAYAALGCLPPTYEPRATGHITEM 269
Query: 123 IEFIKKLKEKGYAYEGSDGVYFEVQKFKDYGKLSGVKIEELRKGARVEPGE-GKKNPEDF 181
+E ++ L E+G+AYE VYF+V+ Y LS ++ELR+ + E GE GK++ DF
Sbjct: 270 VEMMRGLIERGHAYEADGNVYFDVRSLPGYLSLSNQDLDELRQPS--EDGETGKRDLRDF 327
Query: 182 ALWKKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIAQ 241
A+WK AKPGEP W++PWG GRPGWH+ECS M+ KYLGE FDIHGGG DLIFPHHENEIAQ
Sbjct: 328 AMWKAAKPGEPSWETPWGRGRPGWHLECSAMAHKYLGEEFDIHGGGIDLIFPHHENEIAQ 387
Query: 242 SEACFGHEWVRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHYRSP 301
++ FG + RYW+H +V + GEKMSKSLGN V V E+++++ P V+R ++ HYRS
Sbjct: 388 AKG-FGDAFARYWVHNAWVTMSGEKMSKSLGNSVLVSEMVKKWPPVVLRYYLGTPHYRST 446
Query: 302 LDYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREARKKFYDAM 361
++Y+EE L+ A++ R+ ++ + +E A E E F +AM
Sbjct: 447 IEYSEESLREAESAYGRIEGFVQRV-------------TELAGHAVEPAAEVPPAFAEAM 493
Query: 362 DDDFNTAEALKAVFEVSNAINKYILEVDKPKESILRKALEFFKVVSEVFGIFEDYFKEEK 421
DDD +AL V N + DK + V + + + +
Sbjct: 494 DDDLGVPQALAIVHTTVRQGNSALAADDKDAAVARLAEVRAMLGVLGLDPLDAQWAGAQA 553
Query: 422 KGEE-----EKLIELLVEVRKQLRKEKRFDLADKIREELRKLGIQLEDKGQETVW 471
+GE+ + L+ L+++ R+ R K + AD IR++L + G+ +ED Q W
Sbjct: 554 QGEDLRHVVDSLVRLVLDQREGARARKDWATADAIRDQLGQSGLVIEDSPQGPRW 608
>sp|Q9ZE62|SYC_RICPR CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LIGASE) (CYSRS)
>gi|7437724|pir||D71717 cysteine--tRNA ligase (EC
6.1.1.16) (cysS) RP085 - Rickettsia prowazekii
>gi|3860654|emb|CAA14555.1| (AJ235270) CYSTEINYL-TRNA
SYNTHETASE (cysS) [Rickettsia prowazekii]
Length = 457
Score = 344 bits (872), Expect = 2e-93
Identities = 191/481 (39%), Positives = 278/481 (57%), Gaps = 33/481 (6%)
Query: 1 MGIKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEH--R 58
M + +YNTLTR KE P ++MYVCGPTVYD PH+G++R+ + +D++ R +
Sbjct: 1 MKLHLYNTLTRTKEVFNPQDPANIKMYVCGPTVYDNPHIGNSRSVVVYDLLYRIIIKIFG 60
Query: 59 GFTVLMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEH 118
V V N TD+DDKII RA+ G L ++ + F +M L I P+ TEH
Sbjct: 61 KKAVKYVRNITDVDDKIIDRAELLGITINDLTDKVTREFHINMEYLGCMLPTIEPKATEH 120
Query: 119 IDDIIEFIKKLKEKGYAYEGSDGVYFEVQKFKDYGKLSGVKIEELRKGARVEPGEGKKNP 178
ID +IE I++L K +AY + VYF+V +Y +LS +E + +G R+E + KKNP
Sbjct: 121 IDVMIEIIERLIAKDHAYIADNHVYFDVLSAPNYTELSNRNLEAMFEGVRIENSKTKKNP 180
Query: 179 EDFALWKKAKPGEPK---WDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHH 235
+DF LWK AK EP+ + SPWG GRPGWHIECS MS KYLG++FDIHGGG DLIFPHH
Sbjct: 181 QDFVLWKPAKKNEPENINFTSPWGLGRPGWHIECSAMSYKYLGQNFDIHGGGADLIFPHH 240
Query: 236 ENEIAQSEACF-GHEWVRYWLHTGFVMVKGEKMSKSLGNFVTVRELL-QRYSPEVIRLFV 293
NEIAQS F + +YW+H GF+ V G KMSKSLGNF+TVR+L+ ++ EV+RLF+
Sbjct: 241 TNEIAQSRCAFPSSTYAKYWIHNGFLTVNGSKMSKSLGNFITVRDLMDKQIQGEVVRLFL 300
Query: 294 LQKHYRSPLDYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREA 353
L HYR PLDY ++ + AK L+ Y +E+I + + +L
Sbjct: 301 LSSHYRRPLDYNDKAIDDAKKTLDYWYRAIEHINV--QKVDLP----------------- 341
Query: 354 RKKFYDAMDDDFNTAEALKAVFEVSNAINKYILEVDKPKESILRKALEFFKVVSEVFGIF 413
F ++ DD NT A+K + + + + +I + + ++ + + +
Sbjct: 342 -SNFMRSLFDDMNTPLAIKIINDYAKCV--FISKTEAERKFNASAIITCANFIGLMRKTQ 398
Query: 414 EDYFKEEKKGEEEKLIELLVEVRKQLRKEKRFDLADKIREELRKLGIQLEDKGQE-TVWK 472
++F + +E I L+ R + +K+K + LADKIR +L + I LEDK T+W+
Sbjct: 399 YEWFNRD---VDEFYINELINKRLKAKKQKNWLLADKIRNQLLEKKIILEDKSNYITIWR 455
Query: 473 R 473
+
Sbjct: 456 K 456
>sp|P57558|SYC_BUCAI CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LIGASE) (CYSRS)
>gi|10039149|dbj|BAB13183.1| (AP001119) cysteinyl-tRNA
synthetase [Buchnera sp. APS]
Length = 464
Score = 343 bits (871), Expect = 2e-93
Identities = 192/482 (39%), Positives = 276/482 (56%), Gaps = 26/482 (5%)
Query: 3 IKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGFTV 62
+K++NTLT KE P++ V +YVCG TVYD+ H+GH RT++ FD+I RYL GF V
Sbjct: 2 LKIFNTLTSTKEIFTPIKKNRVNLYVCGVTVYDFCHIGHGRTFVVFDMIVRYLRFSGFQV 61
Query: 63 LMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHIDDI 122
V N TDIDDKII ++ + + IK +D + L + D PRVT++ID+I
Sbjct: 62 KYVRNITDIDDKIISKSTKEKKKINTFTASMIKEMHKDFDLLGISVPDEEPRVTDYIDNI 121
Query: 123 IEFIKKLKEKGYAYEGSDG-VYFEVQKFKDYGKLSGVKIEELRKGARVEPGEGKKNPEDF 181
I I L +K +AY +G V F + +YG LS + L G+R+ KKNP DF
Sbjct: 122 IRIITTLIKKKHAYIHKNGDVIFSIDSDPNYGTLSRQSLTSLESGSRIPLNNMKKNPLDF 181
Query: 182 ALWKKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIAQ 241
LWK + E WDSPWG+GRPGWHIECS +++ + S DIHGGG+DL+FPHHENE +Q
Sbjct: 182 ILWKSSNKEEYSWDSPWGKGRPGWHIECSAITNVFFNNSIDIHGGGSDLLFPHHENERSQ 241
Query: 242 SEACFGHE-WVRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHYRS 300
S CF ++ + +W+HTG V++ +KMSKSLGN +R +L+ EV+R F L HYR
Sbjct: 242 S-ICFNNKSMINFWMHTGMVILNNKKMSKSLGNVYFLRNILKDCDAEVLRYFFLSTHYRH 300
Query: 301 PLDYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREARKKFYDA 360
P+ Y E+ L A +L+ LY L + N E +FE +FY+A
Sbjct: 301 PIYYCEKNLDQAYTSLKYLYTALYDTNPFFNNEE------GLNFEL---------EFYNA 345
Query: 361 MDDDFNTAEALKAVFEVSNAINKYILEVDKPKESILRKALEFFKVVSEVFGIFED--YFK 418
M+DDFNT F+++ IN ++ D K + L++ + + + +F+D F
Sbjct: 346 MNDDFNTPAVFSIFFKIARKIN-FLKNKDILKTNKFAFRLKY--LANNLGFLFQDPKEFL 402
Query: 419 EEKKGEE---EKLIELLVEVRKQLRKEKRFDLADKIREELRKLGIQLEDKGQETVWKRVK 475
++K K I+LL+E R R+ K + AD IR++L L I LED +T+W++ K
Sbjct: 403 QKKTTLNLLTLKEIQLLIEKRNIARQSKLWQEADNIRKKLMSLDIILEDLPDKTIWRKNK 462
Query: 476 VS 477
S
Sbjct: 463 KS 464
>sp|O84787|SYC_CHLTR CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LIGASE) (CYSRS)
Length = 477
Score = 341 bits (865), Expect = 1e-92
Identities = 196/479 (40%), Positives = 282/479 (57%), Gaps = 27/479 (5%)
Query: 1 MGIKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGF 60
M + +YNTL+R+KE P+ D V++Y CGPTVYDY H+G+ RTYI D+++R L G+
Sbjct: 1 MDLFLYNTLSREKERFLPVND-PVKLYTCGPTVYDYAHIGNFRTYIFEDLLKRVLLFLGY 59
Query: 61 TVLMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHID 120
+V VMN TD+DDK + A++ G K + +I F D+ L + AD YP T +I
Sbjct: 60 SVYHVMNITDVDDKTLAGARKKGCSLEKYCQPYIHAFFADLETLHILKADAYPHATHYIP 119
Query: 121 DIIEFIKKLKEKGYAYEGSD-GVYFEVQKFKDYGKLSGVKIEELRKGARVEPGE-GKKNP 178
+IE I++L +G AY G D VYF + +F +YG LS + +EELR AR++ E K N
Sbjct: 120 QMIEAIQQLINQGVAYIGQDQSVYFSISQFPNYGALSHLNLEELRNSARIDADEYDKDNL 179
Query: 179 EDFALWKKAKP---GEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHH 235
DF LWK P GE W+SP+G+GRPGWH+ECS+MS LG+S DIH GG D IFPHH
Sbjct: 180 CDFVLWKAYDPDRDGEIFWESPFGKGRPGWHLECSIMSISLLGQSLDIHAGGVDNIFPHH 239
Query: 236 ENEIAQSEACFGHEWVRYWLHTGFVMVKGEKMSKSLGNFVTVRELL-QRYSPEVIRLFVL 294
ENEIAQSE+ +VRYWLH+ ++V +KMSKSLGNF T+R+LL Q +S E +R +L
Sbjct: 240 ENEIAQSESLSHKPFVRYWLHSHHLLVDRKKMSKSLGNFFTLRDLLDQGFSGEEVRYLLL 299
Query: 295 QKHYRSPLDYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREAR 354
Q HYR+ L++T+EGL ++ +L+RL + + R + SY E A +
Sbjct: 300 QGHYRTQLNFTQEGLHASRQSLKRLRDFI------CRLEDPSYPDDIIHPEVATACQSFL 353
Query: 355 KKFYDAMDDDFNTAEALKAVFEVSNAINKYI-------LEVDKP--KESILRKALEFFKV 405
+ F ++ +D N + +L A+F+ IN I E D + + L +
Sbjct: 354 ETFITSLTNDLNISSSLAALFDFIRKINSSIDQHTGIQTETDSSVFSKQDAQHILALLRK 413
Query: 406 VSEVFGIFEDYFKEEKKGEEEKLIELLVEVRKQLRKEKRFDLADKIREELRKLGIQLED 464
+ +V G+ F + EE + LLVE R+ RK K + AD++R+E+ +ED
Sbjct: 414 IDQVLGVLP--FSQPDIPEE---VLLLVEQREAARKVKNWQEADRLRDEILSRSFAIED 467
>pir||F71472 cysteine--tRNA ligase (EC 6.1.1.16) - Chlamydia trachomatis
(serotype D, strain UW3/Cx) >gi|3329246|gb|AAC68377.1|
(AE001350) Cysteinyl tRNA Synthetase [Chlamydia
trachomatis]
Length = 497
Score = 341 bits (865), Expect = 1e-92
Identities = 196/479 (40%), Positives = 282/479 (57%), Gaps = 27/479 (5%)
Query: 1 MGIKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGF 60
M + +YNTL+R+KE P+ D V++Y CGPTVYDY H+G+ RTYI D+++R L G+
Sbjct: 21 MDLFLYNTLSREKERFLPVND-PVKLYTCGPTVYDYAHIGNFRTYIFEDLLKRVLLFLGY 79
Query: 61 TVLMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHID 120
+V VMN TD+DDK + A++ G K + +I F D+ L + AD YP T +I
Sbjct: 80 SVYHVMNITDVDDKTLAGARKKGCSLEKYCQPYIHAFFADLETLHILKADAYPHATHYIP 139
Query: 121 DIIEFIKKLKEKGYAYEGSD-GVYFEVQKFKDYGKLSGVKIEELRKGARVEPGE-GKKNP 178
+IE I++L +G AY G D VYF + +F +YG LS + +EELR AR++ E K N
Sbjct: 140 QMIEAIQQLINQGVAYIGQDQSVYFSISQFPNYGALSHLNLEELRNSARIDADEYDKDNL 199
Query: 179 EDFALWKKAKP---GEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHH 235
DF LWK P GE W+SP+G+GRPGWH+ECS+MS LG+S DIH GG D IFPHH
Sbjct: 200 CDFVLWKAYDPDRDGEIFWESPFGKGRPGWHLECSIMSISLLGQSLDIHAGGVDNIFPHH 259
Query: 236 ENEIAQSEACFGHEWVRYWLHTGFVMVKGEKMSKSLGNFVTVRELL-QRYSPEVIRLFVL 294
ENEIAQSE+ +VRYWLH+ ++V +KMSKSLGNF T+R+LL Q +S E +R +L
Sbjct: 260 ENEIAQSESLSHKPFVRYWLHSHHLLVDRKKMSKSLGNFFTLRDLLDQGFSGEEVRYLLL 319
Query: 295 QKHYRSPLDYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREAR 354
Q HYR+ L++T+EGL ++ +L+RL + + R + SY E A +
Sbjct: 320 QGHYRTQLNFTQEGLHASRQSLKRLRDFI------CRLEDPSYPDDIIHPEVATACQSFL 373
Query: 355 KKFYDAMDDDFNTAEALKAVFEVSNAINKYI-------LEVDKP--KESILRKALEFFKV 405
+ F ++ +D N + +L A+F+ IN I E D + + L +
Sbjct: 374 ETFITSLTNDLNISSSLAALFDFIRKINSSIDQHTGIQTETDSSVFSKQDAQHILALLRK 433
Query: 406 VSEVFGIFEDYFKEEKKGEEEKLIELLVEVRKQLRKEKRFDLADKIREELRKLGIQLED 464
+ +V G+ F + EE + LLVE R+ RK K + AD++R+E+ +ED
Sbjct: 434 IDQVLGVLP--FSQPDIPEE---VLLLVEQREAARKVKNWQEADRLRDEILSRSFAIED 487
>pir||C82737 cysteinyl-tRNA synthetase XF0995 [imported] - Xylella fastidiosa
(strain 9a5c) >gi|9105929|gb|AAF83805.1|AE003937_9
(AE003937) cysteinyl-tRNA synthetase [Xylella
fastidiosa]
Length = 474
Score = 337 bits (854), Expect = 2e-91
Identities = 191/484 (39%), Positives = 256/484 (52%), Gaps = 31/484 (6%)
Query: 1 MGIKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGF 60
M + +YNTL R+ E +PL MYVCGPTVY+Y H+G+AR + F V+ L R
Sbjct: 8 MSLHLYNTLHRRVEPFEPLDPACPTMYVCGPTVYNYVHIGNARGPVVFGVLAALLRRRYG 67
Query: 61 TVLMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHID 120
+ N TD+DDKI AQE G + ERF + EDM L V+P DI P T H+
Sbjct: 68 ALRYARNITDVDDKINTAAQEQGVPISAITERFCAAYREDMKKLGVEPPDIEPEATAHMP 127
Query: 121 DIIEFIKKLKEKGYAYEGSDGVYFEVQKFKDYGKLSGVKIEELRKGARVEPGEGKKNPED 180
II I++L E+ +AY + V F V F DYG+LS EE+ GARVE K++P D
Sbjct: 128 QIIAMIEQLIERQHAYVAMEHVLFAVNSFADYGQLSRRDPEEMLAGARVEIAPYKRDPSD 187
Query: 181 FALWKKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIA 240
F LWK + P WDSPWG GRPGWHIECS M++ +LGE+ DIH GG DL FPHHENEIA
Sbjct: 188 FVLWKPSSDQLPGWDSPWGRGRPGWHIECSAMAAAHLGETIDIHAGGIDLQFPHHENEIA 247
Query: 241 QSEACFGHE-WVRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHYR 299
QS G + R W+H G + +G KMSKSLGN TV L+ ++ PE +R +L HYR
Sbjct: 248 QSRCAHGSSTFARVWMHNGMLNFEGAKMSKSLGNIETVHGLVAKHPPEALRYALLSAHYR 307
Query: 300 SPLDYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREARKKFYD 359
PLD++E + + L RLY TL +D AY A
Sbjct: 308 KPLDWSEALIAQSVRTLNRLYGTL------------------RDLAAYPAHPFIPGNIEA 349
Query: 360 AMDDDFNTAEALKAVFEVSNAINKYILEVDKPKESILRKALEFFKVVSEVFGIF------ 413
A+DDD NT +AL + ++N + + + + AL K +E+ G
Sbjct: 350 ALDDDLNTPQALAELATLANEARIQLADTTHHAAAEVTAALTRLK--AELLGAGLALGLL 407
Query: 414 ----EDYFKEEKKGEEEKLIELLVEVRKQLRKEKRFDLADKIREELRKLGIQLEDKGQET 469
E +F + +E I+ L++ R ++ + F AD IR +L GI LED
Sbjct: 408 QQTPEAWFSQGTNESDETHIQALIDARGAAKQARDFVRADAIRAQLAAEGIVLEDTPHGV 467
Query: 470 VWKR 473
W +
Sbjct: 468 RWMK 471
>gb|AAG19494.1| (AE005041) cysteinyl-tRNA synthetase; CysS [Halobacterium sp.
NRC-1]
Length = 494
Score = 335 bits (849), Expect = 9e-91
Identities = 186/484 (38%), Positives = 274/484 (56%), Gaps = 27/484 (5%)
Query: 5 VYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGFTVLM 64
V NT + ++E +P V +Y CG TV D HLGHAR ++ DV+ R+L H G+ V
Sbjct: 5 VSNTRSGEQEAFEPDDPENVLVYTCGLTVSDDAHLGHARLWVQSDVMTRWLSHAGYGVRH 64
Query: 65 VMNFTDIDDKIIKR--AQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHIDDI 122
V N TD+++KI+ R A G+ +A + + ++DM AL + AD+YPRV+EH+ +I
Sbjct: 65 VQNVTDVNEKIVARVGADGLGDTEAAVAAHYTQSVIDDMRALNLARADVYPRVSEHVPEI 124
Query: 123 IEFIKKLKEKGYAYEGSDGVYFEVQKFKDYGKLSGVKIEELR-KGARVEPGEGKKNPEDF 181
I+ I L + GYAYE VYF+V++F++YG LSG +++EL +G E E K++P DF
Sbjct: 125 IDLIGDLVDAGYAYEAGGSVYFDVRRFEEYGALSGQQVDELDPQGPDAEQAE-KRHPADF 183
Query: 182 ALWKKA--KPGEPK-----------------WDSPWGEGRPGWHIECSVMSSKYLGESFD 222
ALWK P + W SPWGEGRPGWHIECS M+ +L + D
Sbjct: 184 ALWKAGGVSPDDANTHRDDELPPLDGERGQTWASPWGEGRPGWHIECSAMAMTHLDDHID 243
Query: 223 IHGGGNDLIFPHHENEIAQSEACFGHEWVRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQ 282
IH GG DL+FPHHENEIAQSEA G + +WLH + GEKMS SLGNF TV +
Sbjct: 244 IHVGGQDLVFPHHENEIAQSEAASGERFADHWLHVRLLETDGEKMSSSLGNFFTVSNAVA 303
Query: 283 RYSPEVIRLFVLQKHYRSPLDYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEK 342
P V+R+ ++ Y Y+E + A ERL E A+ + K
Sbjct: 304 ERGPNVVRMLLVSTSYTQRQTYSEATVSEATQRWERLQRAHERAADAIDSVAAHAK--PA 361
Query: 343 DFEAYEAIREARKKFYDAMDDDFNTAEALKAVFEVSNAINKYILEVDKPKESILRKALEF 402
D A+ +AR +F AM DFNT A+ A+ E+++A+N+++ D L A++
Sbjct: 362 DDALRTAVADARGEFAAAMRADFNTRAAVSALLELASAVNRHVDGTDTYDYQGLHDAVDA 421
Query: 403 FKVV-SEVFGI-FEDYFKEEKKGEEEKLIELLVEVRKQLRKEKRFDLADKIREELRKLGI 460
F+ + +V G+ F+D E+ + +I+L+++VR+Q R ++ AD +R+ L LG+
Sbjct: 422 FETLGGDVLGLQFDDGAGEDAVSLADDVIDLVLDVREQERTAGNYERADDLRDRLEALGV 481
Query: 461 QLED 464
+ED
Sbjct: 482 SVED 485
>sp|P41259|SYC_HELPY CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LIGASE) (CYSRS)
>gi|7428475|pir||F64630 cysteine--tRNA ligase (EC
6.1.1.16) - Helicobacter pylori (strain 26695)
>gi|2314022|gb|AAD07934.1| (AE000598) cysteinyl-tRNA
synthetase (cysS) [Helicobacter pylori 26695]
Length = 465
Score = 329 bits (835), Expect = 4e-89
Identities = 188/481 (39%), Positives = 280/481 (58%), Gaps = 32/481 (6%)
Query: 5 VYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGFTVLM 64
+Y+T ++K +PL + +YVCGPTVYD HLGHAR+ IAFD++RR LE G+ V++
Sbjct: 3 IYDTKLKQKVPFEPLVQNKANIYVCGPTVYDDAHLGHARSAIAFDLLRRTLELSGYEVML 62
Query: 65 VMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHIDDIIE 124
V NFTDIDDKII +A + + +L+ +I+ + D+NAL VK + P+ +E++D ++
Sbjct: 63 VRNFTDIDDKIINKALKENKSIQELSSIYIESYTRDLNALNVKKPSLEPKASEYLDAMVG 122
Query: 125 FIKKLKEKGYAYEGSDG-VYFEVQKFKDYGKLSGVKIEELRKGARVEPGEGKKNPEDFAL 183
I+ L EK AY+ S+G +Y + K KDYG LS V + G R+ + K+ +DF L
Sbjct: 123 MIETLLEKNIAYQVSNGDIYLDTSKDKDYGSLS-VHNSSIEFG-RIGLVQEKRLEQDFVL 180
Query: 184 WKKAK-PGEPKWDSPWGEGRPGWHIECSVMSSKYLG-----ESFDIHGGGNDLIFPHHEN 237
WK K + +DSP G+GRPGWHIECS M + L DIH GG DL+FPHHEN
Sbjct: 181 WKSYKGDNDVGFDSPLGKGRPGWHIECSSMVFETLALTNTPYQIDIHAGGADLLFPHHEN 240
Query: 238 EIAQSEACFGHEWVRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKH 297
E Q+ FG E +YW+H GFV + EKMSKSLGN V++ L+ Y E++R ++L H
Sbjct: 241 EACQTRCAFGVELAKYWMHNGFVNINNEKMSKSLGNSFFVKDALKNYDGEILRNYLLGVH 300
Query: 298 YRSPLDYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREARKKF 357
YRS L++ EE L +K L+++Y + + + ++K K+
Sbjct: 301 YRSVLNFNEEDLLVSKKRLDKIYRLKQRVLGTLGGINPNFK----------------KEI 344
Query: 358 YDAMDDDFNTAEALKAVFEVSNAINKYILEVDKPKESILR-KALEFFKVVSEVFGI-FED 415
+ M DD N ++AL + + ++ N+ + + PK L+ + L K + E+ GI F+D
Sbjct: 345 LECMQDDLNVSKALSVLESMLSSTNEKLDQ--NPKNKALKGEILANLKFIEELLGIGFKD 402
Query: 416 ---YFKEEKKGEEEKLIELLVEVRKQLRKEKRFDLADKIREELRKLGIQLEDKGQETVWK 472
YF+ E++ IE +E RK+ ++ K F AD IREEL K I L D Q T+W+
Sbjct: 403 PSAYFQLGVSESEKQEIENKIEERKRAKERKDFLKADSIREELLKQKIALMDTPQGTIWE 462
Query: 473 R 473
+
Sbjct: 463 K 463
>sp|Q9ZKW6|SYC_HELPJ CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LIGASE) (CYSRS)
>gi|7437718|pir||D71884 cysteine--tRNA ligase (EC
6.1.1.16) - Helicobacter pylori (strain J99)
>gi|4155389|gb|AAD06399.1| (AE001511) CYSTEINYL-TRNA
SYNTHETASE [Helicobacter pylori J99]
Length = 465
Score = 329 bits (835), Expect = 4e-89
Identities = 187/484 (38%), Positives = 281/484 (57%), Gaps = 36/484 (7%)
Query: 5 VYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGFTVLM 64
+Y+T ++K +PL + +YVCGPTVYD HLGHAR+ IAFD++RR LE G+ V++
Sbjct: 3 IYDTKLKQKVPFEPLVHNKANIYVCGPTVYDDAHLGHARSAIAFDLLRRTLELSGYEVVL 62
Query: 65 VMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHIDDIIE 124
V NFTDIDDKII +A + + +L+ +I+ + D+NAL VK + P+ +E++D ++
Sbjct: 63 VRNFTDIDDKIINKAFKENKSIQELSSIYIESYTRDLNALNVKQPSLEPKASEYLDAMVR 122
Query: 125 FIKKLKEKGYAYEGSDG-VYFEVQKFKDYGKLS--GVKIEELRKGARVEPGEGKKNPEDF 181
I+ L EK +AY S+G +Y + K KDYG LS +E R G E K+ +DF
Sbjct: 123 MIETLLEKNFAYRVSNGDIYLDTSKDKDYGSLSMHNSSVEFSRIGLVQE----KRLEQDF 178
Query: 182 ALWKKAK-PGEPKWDSPWGEGRPGWHIECSVMSSKYLG-----ESFDIHGGGNDLIFPHH 235
LWK K + +DSP G+GRPGWHIECS M + L DIH GG DL+FPHH
Sbjct: 179 VLWKSYKGDNDVGFDSPLGKGRPGWHIECSSMVFETLALANAPYQIDIHAGGTDLLFPHH 238
Query: 236 ENEIAQSEACFGHEWVRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQ 295
ENE Q+ FG E +YW+H GFV + EKMSKSLGN +++ L+ Y E++R ++L
Sbjct: 239 ENEACQTRCAFGVEIAKYWMHNGFVNINNEKMSKSLGNSFFIKDALKNYDGEILRNYLLG 298
Query: 296 KHYRSPLDYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREARK 355
HYRS L++ EE L +K L+++Y + + + ++K K
Sbjct: 299 VHYRSVLNFNEEDLLMSKKRLDKIYRLKQRVLGTLGGINPNFK----------------K 342
Query: 356 KFYDAMDDDFNTAEALKAVFEVSNAINKYILEVDKPKESILR-KALEFFKVVSEVFGI-F 413
+ + M DD N ++AL + + ++ N+ + + PK L+ + L K + E+ GI F
Sbjct: 343 EILECMQDDLNVSKALSVLESMLSSTNEKLDQ--NPKNKALKGEILANLKFIEELLGIGF 400
Query: 414 ED---YFKEEKKGEEEKLIELLVEVRKQLRKEKRFDLADKIREELRKLGIQLEDKGQETV 470
+D YF+ E++ IE +E RK+ +++K F AD IREEL + I L D Q T+
Sbjct: 401 KDPSAYFQLGVSESEKQEIENKIEERKRAKEQKDFLKADSIREELLQQKIALMDTPQGTI 460
Query: 471 WKRV 474
W+++
Sbjct: 461 WEKL 464
>sp|P96862|SYC1_MYCTU CYSTEINYL-TRNA SYNTHETASE 1 (CYSTEINE--TRNA LIGASE 1) (CYSRS 1)
>gi|7437727|pir||B70607 probable cysS protein -
Mycobacterium tuberculosis (strain H37RV)
>gi|1877311|emb|CAB07154.1| (Z92774) cysS [Mycobacterium
tuberculosis]
Length = 469
Score = 327 bits (829), Expect = 2e-88
Identities = 178/476 (37%), Positives = 266/476 (55%), Gaps = 28/476 (5%)
Query: 3 IKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGFTV 62
+++++T + PLR G V +Y+CG TV PH+GH R+ +AFD++RR+L RG+ V
Sbjct: 7 LRLHDTAAGVVRDFVPLRPGHVSIYLCGATVQGLPHIGHVRSGVAFDILRRWLLARGYDV 66
Query: 63 LMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHIDDI 122
+ N TDI+DKI+ +A G + A + F +AL V P PR T HI +
Sbjct: 67 AFIRNVTDIEDKILAKAAAAGRPWWEWAATHERAFTAAYDALDVLPPSAEPRATGHITQM 126
Query: 123 IEFIKKLKEKGYAYEGSDGVYFEVQKFKDYGKLSGVKIEELRKGARVEPGEGKKNPEDFA 182
IE I++L + G+AY G VYF+V + +YG+LSG KI+++ +G V GK++ DF
Sbjct: 127 IEMIERLIQAGHAYTGGGDVYFDVLSYPEYGQLSGHKIDDVHQGEGV--AAGKRDQRDFT 184
Query: 183 LWKKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIAQS 242
LWK KPGEP W +PWG GRPGWH+ECS M+ YLG FDIH GG DL+FPHHENEIAQS
Sbjct: 185 LWKGEKPGEPSWPTPWGRGRPGWHLECSAMARSYLGPEFDIHCGGMDLVFPHHENEIAQS 244
Query: 243 EACFGHEWVRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHYRSPL 302
A G + RYWLH G+V + GEKMSKSLGN +++ +LQR P +R ++ HYRS L
Sbjct: 245 RAA-GDGFARYWLHNGWVTMGGEKMSKSLGNVLSMPAMLQRVRPAELRYYLGSAHYRSML 303
Query: 303 DYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREARKKFYDAMD 362
+++E +Q A L + L +R + + +F +A+D
Sbjct: 304 EFSETAMQDAVKAYVGLEDFLHRVRTRV---------------GAVCPGDPTPRFAEALD 348
Query: 363 DDFNTAEALKAVFEVSNAINKYILEVDKPKESILRKALEFFKVVSEVFGIFEDYFKEEKK 422
DD + AL + V N+ + D + LR A + + + G + E +
Sbjct: 349 DDLSVPIALAEIHHVRAEGNRALDAGD--HDGALRSA-SAIRAMMGILGCDPLDQRWESR 405
Query: 423 GEE-------EKLIELLVEVRKQLRKEKRFDLADKIREELRKLGIQLEDKGQETVW 471
E + L++ ++ R++ R+++ + LAD+IR L++ GI++ D W
Sbjct: 406 DETSAALAAVDVLVQAELQNREKAREQRNWALADEIRGRLKRAGIEVTDTADGPQW 461
>sp|Q9Z6X4|SYC_CHLPN CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LIGASE) (CYSRS)
>gi|7437725|pir||F72016 cysteine--tRNA ligase (EC
6.1.1.16) - Chlamydophila pneumoniae (strains CWL029 and
AR39) >gi|4377255|gb|AAD19070.1| (AE001673) Cysteinyl
tRNA Synthetase [Chlamydophila pneumoniae CWL029]
>gi|7189843|gb|AAF38714.1| (AE002251) cysteinyl-tRNA
synthetase [Chlamydophila pneumoniae AR39]
>gi|8979306|dbj|BAA99140.1| (AP002548) cysteinyl tRNA
synthetase [Chlamydophila pneumoniae J138]
Length = 474
Score = 326 bits (828), Expect = 2e-88
Identities = 186/472 (39%), Positives = 276/472 (58%), Gaps = 24/472 (5%)
Query: 2 GIKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGFT 61
G+ YNT ++KKE P VR+Y CGPTVYDY H+G+ RTY+ D+++R L G++
Sbjct: 8 GLYFYNTASQKKELFFP-NHTPVRLYTCGPTVYDYAHIGNFRTYVFEDILKRTLVFFGYS 66
Query: 62 VLMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHIDD 121
V VMN TD++DK I A + + + + + F ED++ L + AD YP T +I
Sbjct: 67 VTHVMNITDVEDKTIAGASKKNIPLQEYTQPYTEAFFEDLDTLNIARADFYPHATHYIPQ 126
Query: 122 IIEFIKKLKEKGYAYEGSDG-VYFEVQKFKDYGKLSGVKIEELRKGARVEPGE-GKKNPE 179
+I+ I KL E+G AY G D VYF + +F +YGKLS + + LR +R+ E K+NP
Sbjct: 127 MIQAITKLLEQGIAYIGQDASVYFSLNRFPNYGKLSHLDLSSLRCCSRISADEYDKENPS 186
Query: 180 DFALWKKAKP---GEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHE 236
DF LWK P G W+SP+G+GRPGWH+ECS+M+ + LG+S DIH GG D IFPHHE
Sbjct: 187 DFVLWKAYNPERDGVIYWESPFGKGRPGWHLECSIMAMELLGDSLDIHAGGVDNIFPHHE 246
Query: 237 NEIAQSEACFGHEWVRYWLHTGFVMVKGEKMSKSLGNFVTVRELL-QRYSPEVIRLFVLQ 295
NEIAQSEA G + RYWLH+ +++ G+KMSKSLGNF+T+R+LL Q ++ + +R +LQ
Sbjct: 247 NEIAQSEALSGKPFARYWLHSEHLLIDGKKMSKSLGNFLTLRDLLHQEFTGQEVRYMLLQ 306
Query: 296 KHYRSPLDYTEEGL---QHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIRE 352
HYR+ L++TEE L +HA L+ + LE + + + + ++ E
Sbjct: 307 SHYRTQLNFTEEALLACRHALRRLKDFVSRLEGVDLPGESP------LPRTLDSSSQFIE 360
Query: 353 ARKKFYDAMDDDFNTAEALKAVFEVSNAINKYILEVDKPKESILRKALEFFKVVSEVFGI 412
A F A+ +D N + ++F+ + IN I + K L L+ K V V G+
Sbjct: 361 A---FSRALANDLNVSTGFASLFDFVHEINTLIDQGHFSKADSL-YILDTLKKVDTVLGV 416
Query: 413 FEDYFKEEKKGEEEKLIELLVEVRKQLRKEKRFDLADKIREELRKLGIQLED 464
E +++L+ E R++ RK K + +AD +R+E+ G +ED
Sbjct: 417 LP---LTTSVCIPETVMQLVAE-REEARKTKNWAMADTLRDEILAAGFLVED 464
>pir||T47747 cysteine-tRNA ligase - Arabidopsis thaliana
>gi|7572928|emb|CAB87429.1| (AL163763) cysteine-tRNA
ligase [Arabidopsis thaliana]
Length = 489
Score = 321 bits (814), Expect = 1e-86
Identities = 191/486 (39%), Positives = 264/486 (54%), Gaps = 58/486 (11%)
Query: 3 IKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGFTV 62
+ +YNT+T+ KE KP+ G++ +YVCG T YDY H+GHAR ++FD++ RYL H G+ V
Sbjct: 11 LTLYNTMTQLKEVYKPMNPGKIGIYVCGITAYDYSHIGHARAAVSFDLLYRYLRHLGYQV 70
Query: 63 LMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHIDDI 122
V NFTD+DDK A+ GE P L+ RF + +L DM AL+ PRV++H++ I
Sbjct: 71 TYVRNFTDVDDK----AKNCGEKPLDLSNRFCEEYLLDMAALQCLLPTHQPRVSDHMEQI 126
Query: 123 IEFIKKLKEKGYAYEGSDGVYFEVQKFKDYGKLSGVKIEELRKGARVEPGEGKKNPEDFA 182
I+ I+K+ E G Y V+F V K YG+LSG +++ + G RV K+NP DFA
Sbjct: 127 IKMIEKIIENGCGYAVGGDVFFSVDKSPSYGQLSGQRLDHTQAGKRVAVDSRKRNPADFA 186
Query: 183 LWKKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIAQS 242
L K AK GEP W+SPWG GRPGWHIE FDIHGGG DL FPHHENEIAQ+
Sbjct: 187 LRKAAKSGEPSWESPWGHGRPGWHIE------------FDIHGGGADLKFPHHENEIAQT 234
Query: 243 EACFGHEWVRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHYRSPL 302
A V YWLH G V KM KSL NF T+R++ Y P +R F++ YRSPL
Sbjct: 235 CAACEDSGVNYWLHNGHVTNNNVKMGKSLNNFFTIRQIAANYHPLALRHFLMSAQYRSPL 294
Query: 303 DYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREARKKFYDAMD 362
+Y+ L+ + + L L E + + +++ EA E I++ +
Sbjct: 295 NYSVSQLESSSDALYSLSPYREEMSGDVGK-------TQQSAEAKEMIKKVK-------- 339
Query: 363 DDFNTAEALKAVFEVSNAINKYILEVDKPKESILRKALEFFKVVSEVFGI--------FE 414
ALK ++ +I+K K + S++ +E K V EV + +
Sbjct: 340 ------NALKF---INVSISKLKKMQKKQRMSLVVSLVEVEKAVREVLDVLGLLTTLSYG 390
Query: 415 DYFKEEKK--------GEEEKLIELLVEVRKQLRKEKRFDLADKIREELRKLGIQLEDKG 466
+ K+ K+ GEEE L +E R RK K F +D+IRE L GI LED
Sbjct: 391 ELLKDMKQKALTRAGMGEEEVLQR--IEERNMARKSKDFRRSDRIRELLAFKGIFLEDVP 448
Query: 467 QETVWK 472
+TVW+
Sbjct: 449 GDTVWR 454
>gb|AAF18749.1|AF162864_1 (AF162864) cysteinyl-tRNA synthetase [Rhodothermus marinus]
Length = 504
Score = 317 bits (803), Expect = 2e-85
Identities = 193/507 (38%), Positives = 277/507 (54%), Gaps = 50/507 (9%)
Query: 3 IKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGFTV 62
+++YNTLTR E + PL +R+Y CGPTVY Y H+G+ R+++ D+I R + G+
Sbjct: 8 LRLYNTLTRSIEPIYPLERNPLRLYACGPTVYTYAHIGNFRSFLTADLIVRVAQALGWQT 67
Query: 63 LMVMNFTDI-------------DDKIIK--RAQETGEDPG--KLAERFIKVFLEDMNALK 105
+ V N TD+ DK+ + R++E P LA + + FLED LK
Sbjct: 68 VYVCNVTDVGHLTVDDYADASGQDKLERALRSEEGRRFPNIWDLARYYTQAFLEDWQTLK 127
Query: 106 VKPADIYPRVTEHIDDIIEFIKKLKEKGYAYEGSDGVYFEVQKFKDYGKLSGVKI-EELR 164
+ D+ PR TEHI I I++L + G+AYE GVYF V F DYGKLSG + E+L
Sbjct: 128 LVEPDVRPRATEHIRQQILAIEQLVKTGHAYETRQGVYFHVPSFPDYGKLSGNRDPEQLA 187
Query: 165 KGAR-VEPGEGKKNPEDFALWKKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDI 223
+ R V K++P DFALWKK + +W SPWG G PGWHIECSVMS +YLGE+FD+
Sbjct: 188 RAVRDVVQDPEKRDPRDFALWKKDEKHLMQWYSPWGWGFPGWHIECSVMSMEYLGETFDL 247
Query: 224 HGGGNDLIFPHHENEIAQSEACFGHEWVRYWLHTGFVMVKGEKMSKSLGNFVTVRELL-- 281
H GG DLIFPHHE EIAQ+E+ G RYW+HT F++V+GEKMSKS GNF TVREL+
Sbjct: 248 HLGGEDLIFPHHECEIAQAESLTGKPLARYWVHTRFLLVEGEKMSKSKGNFFTVRELIFP 307
Query: 282 -----QRYSPEVIRLFVLQKHYRSPLDYTEEGLQHAKNNLERLYNTLENIRIAMRNAELS 336
Q P +R ++ YR PL++T + L+ + ++R ++ A+
Sbjct: 308 PEAGGQGIDPMALRYALISGKYREPLNFTRKHLRDSIRIVQRYQEAARHVEAAL------ 361
Query: 337 YKWSEKDFEAYEAIREARKKFYD----AMDDDFNTAEALKAVFEVSNAINKYILEVDKPK 392
E D + + + YD A+ DD NT AL A E I + ++++
Sbjct: 362 ----ESDRSGPDRLGDRLSTIYDKTLEALCDDLNTPVALAAALEGVKLILGFGDQLNRAS 417
Query: 393 ESILRKALEFFKVVSEVFGIFED------YFKEEKKGEEEKLIELLVEVRKQLRKEKRFD 446
R+ L+ + + G + + EK EK+ LL E R R+ + F
Sbjct: 418 AESARRWLD---QIDALLGFVYPPERPCAHTRREKDPFVEKVERLLAE-RDAARRARDFA 473
Query: 447 LADKIREELRKLGIQLEDKGQETVWKR 473
AD IRE+L ++G+++ D + T W+R
Sbjct: 474 RADAIREQLLQMGVEVMDTPEGTRWRR 500
>dbj|BAB13978.1| (AK022180) unnamed protein product [Homo sapiens]
Length = 564
Score = 314 bits (795), Expect = 2e-84
Identities = 191/504 (37%), Positives = 279/504 (54%), Gaps = 43/504 (8%)
Query: 2 GIKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHR-GF 60
G++VYN+LT +KE L Y CGPTVYD+ HLGHA +Y+ FD+IRR L G
Sbjct: 51 GVQVYNSLTGRKEPLIVAHAEAASWYSCGPTVYDHAHLGHACSYVRFDIIRRILTKVFGC 110
Query: 61 TVLMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHID 120
+++MVM TD+DDKIIKRA E P LA + + F +DM ALKV P +Y RVTE+I
Sbjct: 111 SIVMVMGITDVDDKIIKRANEMNISPASLASLYEEDFKQDMAALKVLPPTVYLRVTENIP 170
Query: 121 DIIEFIKKLKEKGYAYEGSDG-VYFEVQKFKD-YGKLSGVKIEELRKGARVEPGEG-KKN 177
II FI+ + +G AY + G VYF+++ D YGKL GV G EP + K++
Sbjct: 171 QIISFIEGIIARGNAYSTAKGNVYFDLKSRGDKYGKLVGVV-----PGPVGEPADSDKRH 225
Query: 178 PEDFALWKKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHEN 237
DFALWK AKP E W SPWG GRPGWHIECS ++S G DIH GG DL FPHHEN
Sbjct: 226 ASDFALWKAAKPQEVFWASPWGPGRPGWHIECSAIASMVFGSQLDIHSGGIDLAFPHHEN 285
Query: 238 EIAQSEACFG-HEWVRYWLHTGFVMVKG--EKMSKSLGNFVTVRELLQRYSPEVIRLFVL 294
EIAQ E +W Y+LH+G + KG EKMSKSL N++T+++ L+ +SP+V R F L
Sbjct: 286 EIAQCEVFHQCEQWGNYFLHSGHLHAKGKEEKMSKSLKNYITIKDFLKTFSPDVFRFFCL 345
Query: 295 QKHYRSPLDYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREAR 354
+ YRS +DY++ + A+ L L + LE+ R M+ S ++ +E + +
Sbjct: 346 RSSYRSAIDYSDSAMLQAQQLLLGLGSFLEDARAYMKGQLAC--GSVREAMLWERLSSTK 403
Query: 355 KKFYDAMDDDFNTAEALKAVFEVSN----AINKYILEVDKPKESILRKAL-----EFFKV 405
+ A+ DDF+T + A+ +++ + + E + P+ + A+ +FF+
Sbjct: 404 RAVKAALADDFDTPRVVDAILGLAHHGNGQLRASLKEPEGPRSPAVFGAIISYFEQFFET 463
Query: 406 V----------------SEVFGIFEDYFKEEKKGEEEKLI--ELLVEVRKQ--LRKEKRF 445
V + + G+ ++ + +K + L E + R+Q L ++
Sbjct: 464 VGISLANQQYVSGDGSEATLHGVVDELVRFRQKVRQFALAMPEATGDARRQQLLERQPLL 523
Query: 446 DLADKIREELRKLGIQLEDKGQET 469
+ D +R L GI ++D+ T
Sbjct: 524 EACDTLRRGLTAHGINIKDRSSTT 547
>sp|Q9PPB8|SYC_CAMJE CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LIGASE) (CYSRS)
>gi|11271631|pir||B81352 cysteine--tRNA ligase (EC
6.1.1.16) Cj0802 [imported] - Campylobacter jejuni
(strain NCTC 11168) >gi|6968248|emb|CAB73067.1|
(AL139076) cysteinyl-tRNA synthetase [Campylobacter
jejuni]
Length = 462
Score = 304 bits (771), Expect = 1e-81
Identities = 176/471 (37%), Positives = 266/471 (56%), Gaps = 28/471 (5%)
Query: 13 KEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGFTVLMVMNFTDID 72
KE++K L ++ +Y+CGPTVYD HLGHAR+ + FD++RR L +G V N+TDID
Sbjct: 9 KEKIK-LDKKDISIYLCGPTVYDDAHLGHARSSVCFDLLRRVLLAQGNRVKFARNYTDID 67
Query: 73 DKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHIDDIIEFIKKLKEK 132
DKI+K+ ++G+ ++ E +IK + EDM L V D PR T +I +++ IKKL +
Sbjct: 68 DKILKKMAQSGQTLEEITEFYIKSYEEDMRVLNVLDPDFKPRATHYITAMLDLIKKLAKD 127
Query: 133 GYAYEGSDGVYFEVQKFKDYGKLSGVKIEELRKGARVEPGEGKKNPEDFALWKKAKPGEP 192
G+ Y DG+YF+ K + Y LS +EE +R+ K+N DF LWK E
Sbjct: 128 GFVYTLEDGIYFDTSKDEKYLSLSNRNLEE--NISRLSNEVQKRNESDFVLWKF---DEN 182
Query: 193 KWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIAQSEACFGHEWVR 252
++S +G+GRPGWH EC M + DIH GG DL+FPHHENE AQ +
Sbjct: 183 FYESEFGKGRPGWHTECVAMIDSIFENTLDIHAGGIDLLFPHHENEAAQCRCGCKRKLAN 242
Query: 253 YWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHYRSPLDYTEEGLQHA 312
WLH GFV + GEKMSKSL N +++ L+ + E +R ++L HYRS +Y+ L++A
Sbjct: 243 IWLHNGFVKIDGEKMSKSLNNSFFIKDALKEFMGEALRFYLLSSHYRSHFNYSLSDLENA 302
Query: 313 KNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAI---REARKKFYDAMDDDFNTAE 369
K L++ Y + + + E+S DF+ I E K+ + ++DD N ++
Sbjct: 303 KKRLDKFYRLKKRLDL----GEIS------DFDVLNDIGIKSEIAKQILEILNDDLNVSK 352
Query: 370 ALKAVFEVSNAINKYILEVDK-PKESILRKAL-EFFKVVSEVFGI-FED---YFKEEKKG 423
AL + + ++ N LE+DK K IL++ + E ++++FG F D YF+
Sbjct: 353 ALALLDDFISSAN---LELDKESKNKILKQNIKEALSELAKIFGFGFMDATLYFQWGVSK 409
Query: 424 EEEKLIELLVEVRKQLRKEKRFDLADKIREELRKLGIQLEDKGQETVWKRV 474
EE + IE L+ R + +K K F+ AD IRE+L I L D T+W+++
Sbjct: 410 EEREEIEKLILERTEAKKNKDFNTADAIREQLNSKKITLLDTPNGTIWEKI 460
>gb|AAF58291.1| (AE003815) CG8257 gene product [Drosophila melanogaster]
Length = 558
Score = 285 bits (721), Expect = 9e-76
Identities = 184/505 (36%), Positives = 276/505 (54%), Gaps = 46/505 (9%)
Query: 2 GIKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYL-EHRGF 60
GI +YN R+K L V Y CGPTVYD HLGHA TY+ D+++R L ++
Sbjct: 47 GINIYNHGLRQKVPLILRNPQMVTWYTCGPTVYDSAHLGHASTYVKVDILQRILRDYFKI 106
Query: 61 TVLMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHID 120
++ MN TD+DDKIIKRAQ G D K+A + F +DM L V+ D+ VT +
Sbjct: 107 NLVTAMNITDVDDKIIKRAQLAGLDWQKMARAYEAEFRQDMLRLNVQAPDVRSHVTTTMP 166
Query: 121 DIIEFIKKLKEKGYAYEGSDG-VYFEVQKFKDYGKLSGVKIEELRKGARVEPGEGKKNPE 179
II+FI++L + AY D VYF+V K K+YGKL + + E +++P K+N
Sbjct: 167 VIIQFIQQLIDGKQAYVTPDNSVYFDVSKSKNYGKLQNLGLSE----DKLDPI--KRNTA 220
Query: 180 DFALWKKAKPG-EPKWDSPWG-EGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHEN 237
DFALWK K G EP W +PWG EGRPGWHIECS ++ + G DIH GG DL FPHHEN
Sbjct: 221 DFALWKARKSGSEPTWAAPWGGEGRPGWHIECSAIAGLFFGRQLDIHAGGLDLRFPHHEN 280
Query: 238 EIAQSEACF-GHEWVRYWLHTGFVMVKG--EKMSKSLGNFVTVRELLQRYSPEVIRLFVL 294
E AQ A + +WV YW+HTG + + G EKMSKSLGN ++V ELL++Y+ + R+ L
Sbjct: 281 EEAQCCARYKTDQWVNYWVHTGQLHMVGDREKMSKSLGNTISVSELLKKYTADEFRMACL 340
Query: 295 QKHYRSPLDYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREAR 354
+YR+ + Y+++ + A+ L+R N ++ + + + E +A +
Sbjct: 341 LSNYRNAMPYSDQLMVTARQTLQRFRNFQADLSAYTQFLKPVHLLDEGALKA--QLTHTV 398
Query: 355 KKFYDAMDDDFNTAEALKAVFEVSNAINKYILE--VDKPKE-----SILRKALEFFKVVS 407
+F + + DDF+TA A+ + + ++I++ I E VD +E +L A F
Sbjct: 399 TEFDNCLRDDFDTARAISVLIDQMSSISRCINEQQVDAQEEPAYCIDLLLAAGNFINRAI 458
Query: 408 EVFGIFEDYFKEEKKGEEEK------------LIELLVEVRKQLRKE---------KRFD 446
FG+ E ++K+ +EK L+ ++ VR ++R+ +
Sbjct: 459 VTFGLSE---LQDKESLQEKVSFTDHSIDPNLLVNDVINVRGRMRERATSGNVKNPQLLA 515
Query: 447 LADKIREELRKLGIQLEDKGQETVW 471
D++R L++ GIQ+ D Q + W
Sbjct: 516 ACDELRSLLQQHGIQVRDHKQGSSW 540
>pir||F53402 cysteine--tRNA ligase (EC 6.1.1.16) - Bacillus stearothermophilus
(fragment)
Length = 221
Score = 284 bits (720), Expect = 1e-75
Identities = 134/216 (62%), Positives = 163/216 (75%)
Query: 3 IKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGFTV 62
I++YNTLTRKKE +PL +V+MYVCGPTVY+Y H+G+AR I FD IRRYLE RG+ V
Sbjct: 4 IRLYNTLTRKKEPFEPLEPNKVKMYVCGPTVYNYIHIGNARAAIVFDTIRRYLEFRGYDV 63
Query: 63 LMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHIDDI 122
V NFTD+DDK+IK A+E GE +AERFI+ + ED+ AL K ADI+PRVTE+I I
Sbjct: 64 TYVSNFTDVDDKLIKAARELGESVPAIAERFIEAYFEDIQALGCKKADIHPRVTENIGTI 123
Query: 123 IEFIKKLKEKGYAYEGSDGVYFEVQKFKDYGKLSGVKIEELRKGARVEPGEGKKNPEDFA 182
IEFI+ L +KGYAYE VY+ +KF YGKLS I+EL+ GAR+E GE K +P DFA
Sbjct: 124 IEFIQALIDKGYAYEVDGDVYYRTRKFPGYGKLSHQSIDELQAGARIEVGEKKDDPLDFA 183
Query: 183 LWKKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLG 218
LWK AK GE WDSPWG+GRPGWHIECS M+ +YLG
Sbjct: 184 LWKAAKEGEICWDSPWGKGRPGWHIECSAMAGRYLG 219
>sp|O83129|SYC_TREPA CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LIGASE) (CYSRS)
>gi|7437722|pir||D71368 cysteine--tRNA ligase (EC
6.1.1.16) (cysS) - syphilis spirochete
>gi|3322350|gb|AAC65085.1| (AE001193) cysteinyl-tRNA
synthetase (cysS) [Treponema pallidum]
Length = 520
Score = 282 bits (715), Expect = 4e-75
Identities = 182/530 (34%), Positives = 265/530 (49%), Gaps = 66/530 (12%)
Query: 1 MGIKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGF 60
M ++VYNTLTR++E +P G VR+Y CGPTVY+YPHLG+ R Y+ D +RR L G+
Sbjct: 1 MALRVYNTLTRQQEHFQPWEHGHVRLYGCGPTVYNYPHLGNLRAYVFQDTVRRTLHFLGY 60
Query: 61 TVLMVMNFTDI----------DDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPAD 110
V VMN TD+ +DK+++ AQ G ++A + F D L ++
Sbjct: 61 RVTYVMNITDVGHLESDADSGEDKLVRSAQAHGHSVLQVAAHYRAAFFRDTALLGIEEPS 120
Query: 111 IYPRVTEHIDDIIEFIKKLKEKGYAYEGSDGVYFEVQKFKDYGKLSGVKIEELRKG---- 166
I ++ I D+I FI++L +G+AY VYF+V+ F Y +E++++G
Sbjct: 121 IVCNASDCIQDMIAFIEQLLARGHAYCAGGNVYFDVRSFPSYESFGSAAVEDVQEGEDAA 180
Query: 167 -ARVEPGEGKKNPEDFALW---KKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFD 222
ARV K++ DF LW K WDSPWG G PGWHI CS MS K+LG D
Sbjct: 181 RARVAHDTHKRDARDFVLWFTRSKFVRHALTWDSPWGRGYPGWHIGCSAMSMKFLGPRCD 240
Query: 223 IHGGGNDLIFPHHENEIAQSEACFGHEWVRYWLHTGFVMVKGE----------------- 265
IH GG D I HH NE AQ EA G WVRYWLH F++++ +
Sbjct: 241 IHIGGVDHIRVHHRNERAQCEAITGAPWVRYWLHHEFLLMQLQKRAVHADMGSSVVSSFS 300
Query: 266 KMSKSLGNFVTVRELLQR-YSPEVIRLFVLQKHYRSPLDYTEEGLQHAKNNLERLYNTLE 324
KMSKS G F+T+ L +R + P R F+L YR+ L ++ + L+ A+ +
Sbjct: 301 KMSKSCGQFLTLSSLQERGFQPADFRFFLLSGQYRTQLAFSWDALKTARAARRSFVRRVA 360
Query: 325 NIRIAMRNAELSYKWSEKDFEAYEAIREARKK--------FYDAMDDDFNTAEALKAVFE 376
+ A R S + + + A E + E+R F A++DDF+T AL
Sbjct: 361 RVVDAARATTGSVRGTSAECAA-ERVCESRASESELLLTDFRAALEDDFSTPRAL----- 414
Query: 377 VSNAINKYILEVDKPKESILRKALEFFKVVSEVFGIFEDYFKE------------EKKGE 424
+A+ K + + P S+ AL+ V + GI ++ ++
Sbjct: 415 --SALQKLVRDTSVP-PSLCVSALQVADTVLGL-GIIQEATASLSAQVPAGDTLPQRPLP 470
Query: 425 EEKLIELLVEVRKQLRKEKRFDLADKIREELRKLGIQLEDKGQETVWKRV 474
E+ I LV R R+ + F AD+IR +L+ GI+LED T+WKRV
Sbjct: 471 SEEWIGQLVRARAHARQTRDFPRADEIRRQLKAEGIELEDTHLGTIWKRV 520
>pir||H82930 cysteinyl-tRNA synthetase UU123 [imported] - Ureaplasma urealyticum
>gi|6899081|gb|AAF30529.1|AE002113_3 (AE002113)
cysteinyl-tRNA synthetase [Ureaplasma urealyticum]
Length = 436
Score = 262 bits (662), Expect = 7e-69
Identities = 154/459 (33%), Positives = 243/459 (52%), Gaps = 25/459 (5%)
Query: 3 IKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGFTV 62
+K+Y++ + +L + D + +Y CGPTVY++ H+G+AR I DV+ R+L+
Sbjct: 1 MKLYDSYSN---QLVEINDELISIYNCGPTVYNHIHIGNARPLITMDVLYRFLKKHNIKT 57
Query: 63 LMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHIDDI 122
V+N TDIDDKII A +++E + +L+ AL I P+V+ H+D I
Sbjct: 58 KYVLNITDIDDKIINYALANNLKELEVSEYYFNEYLKIKKALNTLEM-INPKVSTHMDKI 116
Query: 123 IEFIKKLKEKGYAYEGSDGVYFEVQKFKDYGKLSGVKIEELRKGARVEPGEGKKNPEDFA 182
I++I+KL +K Y D VYF+ +K +YG+LS +E G R+E K NP DF
Sbjct: 117 IDYIQKLIDKQAGYFIGDDVYFDTKKALNYGQLSKRDLENDIVGMRIESAANKHNPNDFI 176
Query: 183 LWKKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIAQS 242
LWKK G W++PWG GRPGWH ECS + + Y+GE IHGGG DL FPHHENE AQ+
Sbjct: 177 LWKKTNKGI-MWNTPWGIGRPGWHSECSCLINTYIGEQVSIHGGGIDLKFPHHENENAQN 235
Query: 243 EACFGHEWVRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHYRSPL 302
+ + + W+H G V + EKMSKSL NF+ V++LL Y +V+R F Q Y+ P+
Sbjct: 236 QVLYNKNLAKVWMHFGLVNINNEKMSKSLNNFILVKDLLAEYDYQVVRWFFYQADYKQPI 295
Query: 303 DYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREARKKFYDAMD 362
++ E ++ + + ++ N + N + +Y + ++ I + + F + ++
Sbjct: 296 KFSHEIMKQNEKEILKIKNAIYNAK--------NYLYFNNQLKSLTQI-DHFELFDERIN 346
Query: 363 DDFNTAEALKAVFEVSNAINKYILEVDKPKESILRKALEFFKVVSEVFGI-FEDYFKEEK 421
DD + + + IN I E E L+ L + ++ GI F D +E
Sbjct: 347 DDLDFVGIVDLIHISVKKINILIKENKDMNE--LKLNLTQLLYMLDILGINFVDLHNDEN 404
Query: 422 KGEEEKLIELLVEVRKQLRKEKRFDLADKIREELRKLGI 460
L+ K +K + AD++R++L +GI
Sbjct: 405 LA--------LLNTWKNYVDKKDYVKADELRKQLINIGI 435
>sp|O51545|SYC_BORBU CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LIGASE) (CYSRS)
>gi|7428476|pir||F70174 cysteine--tRNA ligase (EC
6.1.1.16) cysS - Lyme disease spirochete
>gi|2688519|gb|AAC66952.1| (AE001161) cysteinyl-tRNA
synthetase (cysS) [Borrelia burgdorferi]
Length = 480
Score = 258 bits (653), Expect = 8e-68
Identities = 166/490 (33%), Positives = 257/490 (51%), Gaps = 28/490 (5%)
Query: 1 MGIKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGF 60
M +K+YNT T+ EL + V++Y CGPTVY+Y H+G+ RTYI D++ + L G+
Sbjct: 1 MILKLYNTRTKDFSELTNFEN--VKVYACGPTVYNYAHIGNFRTYIFGDLLIKTLRFLGY 58
Query: 61 TVLMVMNFTDI----------DDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPAD 110
V MN TDI +DK+ K A+E G +++E F + F D L + D
Sbjct: 59 KVNYAMNITDIGHLTGDLDDGEDKVAKTAREKGLTVYEISEFFTEAFFNDCRKLNIVYPD 118
Query: 111 IYPRVTEHIDDIIEFIKKLKEKGYAYEGSDGVYFEVQKFKDYGKLSGVK-IEELRKGARV 169
++HI +IE +K L+EK Y + VYF+ FK YG+++G+ I++ RV
Sbjct: 119 KVLVASKHIPIMIEVVKILEEKKITYFSNGNVYFDTSCFKSYGEMAGIDLIDKDMTLPRV 178
Query: 170 EPGEGKKNPEDFALW---KKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGG 226
+ + K+N DF LW K K E KWDSPWG G P WH+EC+ M+ +Y ++ DIH G
Sbjct: 179 DVDKFKRNKTDFVLWFTNSKFKDQEMKWDSPWGFGYPSWHLECAAMNLEYFKDALDIHLG 238
Query: 227 GNDLIFPHHENEIAQSEACFGHEWVRYWLHTGFVMVKGEKMSKSLGNFVTVRELL-QRYS 285
G D I HH NEIA +E +W ++H F+++ KMSKS GNF+TV++L Q +S
Sbjct: 239 GVDHIGVHHINEIAIAECFLNKKWCDVFVHGEFLIMDYNKMSKSRGNFITVKDLEDQNFS 298
Query: 286 PEVIRLFVLQKHYRSPLDYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFE 345
P R L HYR+ L ++ + LQ +K E L N L ++ +L+ +
Sbjct: 299 PLDFRYLCLTSHYRNQLKFSLDNLQASKIARENLINKLSYFYESLDPVDLNTLNKDLKNF 358
Query: 346 AYEAIREARKKFYDAMDDDFNTAEALKAVFEVSNAINKYILEVDKPKESILRKALEFFKV 405
+ +E F + + D N A+ L ++E+ + N + S LR A F ++
Sbjct: 359 GFSVEKEYYDSFVEKISFDLNVAQGLALLWEIIKSDNLSFV-------SKLRLAFIFDEI 411
Query: 406 VSEVFGIFEDYFKEEKKGEE--EKLIELLVEVRKQLRKEKRFDLADKIREELRKLGIQLE 463
+S + E+ K + + ++ ++ L+E R+ + EK F AD+IR+ K G L
Sbjct: 412 MS--LNLREEILKNLQNHDVVIDENMKALIEERRIAKCEKNFKRADEIRDFFAKKGFVLV 469
Query: 464 DKGQETVWKR 473
D + T KR
Sbjct: 470 DTKEGTKVKR 479
>sp|O07045|SYC_AZOBR CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LIGASE) (CYSRS)
Length = 448
Score = 252 bits (636), Expect = 8e-66
Identities = 177/478 (37%), Positives = 236/478 (49%), Gaps = 36/478 (7%)
Query: 1 MGIKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGF 60
M + +YNTLTR+KE +P+ V MYVCGPTVYD H+G+AR + FD++ R L
Sbjct: 1 MPLDLYNTLTRRKERFEPMTPDRVGMYVCGPTVYDTAHIGNARP-VVFDLLFRLLRRLYP 59
Query: 61 TVLMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHID 120
V V N T DDKII R TG D G A++ + L + I PR T HI
Sbjct: 60 AVTYVRNITASDDKIIDRRATTGADRG--ADQAHRGPLPRRHGPLNAAPTIEPRATHHIS 117
Query: 121 DIIEFIKKLKEKGYAYEGSDGVYFEVQKFKDYGKLSGVKIEELRKGARVEPGEGKKNPED 180
++ I L E ++++ G+LS ++E+ GARVE K++ D
Sbjct: 118 HMVALIGLLIEPATPTPRKGTCCSPCRRWRSTGQLSRRSLDEMIAGARVEVAPYKRDSSD 177
Query: 181 FALWKKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIA 240
F LWK + G+P WDSPWG GRPGWHIECS M+ ++LG +FDIHGGG DLI P HENEIA
Sbjct: 178 FVLWKPSTDGQPGWDSPWGRGRPGWHIECSAMAKEHLGVTFDIHGGGLDLILPDHENEIA 237
Query: 241 QSE-ACFGHEWVRYWLHTGFVMVKG-EKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHY 298
QS A G RYW+H +G +MSKSLGN LL R F H
Sbjct: 238 QSRCAHAGEPLARYWVHQRLRDRRGARRMSKSLGN------LLHR-GTSCWTEFPGGGHP 290
Query: 299 RSPLDYTEEGL---QHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREARK 355
Y GL + +K L+R Y L A AEL +
Sbjct: 291 LGVRPYRSRGLPEAEESKATLDRWYQALRG-DPAPAQAELPF------------------ 331
Query: 356 KFYDAMDDDFNTAEALKAVFEVSNAINKYILEVDKPKESILRKALEFFKVVSEVFGIFED 415
A++DD N+ A+ + E+++A+NK E +K ++ E + E +
Sbjct: 332 DVLAALEDDLNSPLAISHLHELASAVNKATGEAEKAAAKGRCRSAERW-AAPETRSVV-P 389
Query: 416 YFKEEKKGEEEKLIELLVEVRKQLRKEKRFDLADKIREELRKLGIQLEDKGQETVWKR 473
E + I+ +E R RK K + AD+IR+EL LGI LED Q T WKR
Sbjct: 390 LGAEGAAALSDADIQQRIEDRSAARKAKNYAEADRIRKELADLGIVLEDGPQGTTWKR 447
>sp|Q09860|YAF6_SCHPO PUTATIVE CYSTEINYL-TRNA SYNTHETASE C29E6.06C (CYSTEINE--TRNA
LIGASE) (CYSRS) >gi|7490756|pir||S62512 probable
cysteinyl-trna synthetase [imported] - fission yeast
(Schizosaccharomyces pombe) >gi|7492503|pir||T38507
probable cysteinyl-trna synthetase - fission yeast
(Schizosaccharomyces pombe) >gi|1044932|emb|CAA91428.1|
(Z66525) putative cysteinyl-trna synthetase
[Schizosaccharomyces pombe] >gi|6723893|emb|CAB66469.1|
(AL136538) putative cysteinyl-trna synthetase
[Schizosaccharomyces pombe]
Length = 754
Score = 251 bits (635), Expect = 1e-65
Identities = 135/348 (38%), Positives = 206/348 (58%), Gaps = 21/348 (6%)
Query: 88 KLAERFIKVFLEDMNALKVKPADIYPRVTEHIDDIIEFIKKLKEKGYAYEGSDG-VYFEV 146
KLA + F +DM L V P RV+E++ +I++F++++ ++GYAY +DG VYF+
Sbjct: 220 KLAAYWEDDFNKDMANLNVLPPTAVTRVSEYVPEIVDFVQRIIDRGYAYPVTDGSVYFDT 279
Query: 147 QKFKDYGKLSGVKIEELRKGAR--VEPGEG-------KKNPEDFALWKKAKPGEPKWDSP 197
+ F+ G K+E KG R + GEG KK P DFALWK +KPGEP WDSP
Sbjct: 280 EAFEKGGHFYA-KLEPWNKGNRELIAEGEGSLAALTGKKRPGDFALWKASKPGEPSWDSP 338
Query: 198 WGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIAQSEACFG-HEWVRYWLH 256
W +GRPGWHIECSVM+S LG + DIH GG DL FPHH+NE+AQSEA F +WV Y+ H
Sbjct: 339 WSKGRPGWHIECSVMASALLGSNIDIHSGGIDLAFPHHDNELAQSEAYFDCPQWVNYFFH 398
Query: 257 TGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHYRSPLDYTEEGLQHAKNNL 316
G + ++G+KMSKSL NF+T++E+L++++P +RL L + + + LD+ E L + N
Sbjct: 399 AGHLHIEGQKMSKSLKNFITIKEILKKFTPRQLRLAFLLQQWNTQLDFKETLLAYVLNIE 458
Query: 317 ERLYNTLENIRIAMRNAE--------LSYKWSEKDFEAYEAIREARKKFYDAMDDDFNTA 368
+ L N +R M E + K+ + + E E ++ ++ + A+ D FNT
Sbjct: 459 QALENFFRTVRALMNETEGVSANGGHVPEKFDKLEIELLEKFQQTQQNTHLALCDSFNTP 518
Query: 369 EALKAVFEVSNAINKYILEV-DKPKESILRKALEFFKVVSEVFGIFED 415
++ + + N YI EV +P +L + + + ++FG+ E+
Sbjct: 519 LVMQHIDNLVTQANIYIREVGQQPCSRLLGQIASWITSMLQIFGLDEN 566
Score = 77.3 bits (187), Expect = 4e-13
Identities = 38/78 (48%), Positives = 49/78 (62%), Gaps = 2/78 (2%)
Query: 5 VYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLE-HRGFTVL 63
VYNTLT K + Y CGPTVYD H+GHAR Y+ D++RR L+ + G+ +
Sbjct: 23 VYNTLTHSKVPFVS-NGSNLTWYCCGPTVYDASHMGHARNYVTTDILRRILQSYFGYNIT 81
Query: 64 MVMNFTDIDDKIIKRAQE 81
V N TDIDDKII RA++
Sbjct: 82 FVQNVTDIDDKIILRARQ 99
>sp|P47495|SYC_MYCGE CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LIGASE) (CYSRS)
>gi|1361470|pir||I64227 cysteine--tRNA ligase (EC
6.1.1.16) - Mycoplasma genitalium
>gi|3844851|gb|AAC71473.1| (U39704) cysteinyl-tRNA
synthetase (cysS) [Mycoplasma genitalium]
Length = 428
Score = 249 bits (629), Expect = 5e-65
Identities = 156/438 (35%), Positives = 230/438 (51%), Gaps = 35/438 (7%)
Query: 24 VRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGFTVLMVMNFTDIDDKIIKRAQETG 83
+ +Y+CGPTVY+ HLG+ R I FDV+ R L+ +TV V N TDIDDKIIK AQ+
Sbjct: 18 INIYLCGPTVYNDLHLGNTRPLIVFDVLNRVLKKAKYTVNFVQNITDIDDKIIKIAQQQE 77
Query: 84 EDPGKLAERFI---KVFLEDMNALKVKPADIYPRVTEHIDDIIEFIKKLKEKGYAYEGS- 139
+ ++ I K L+ +N L +K + ++TE ID I ++I +L + +AY +
Sbjct: 78 VSESVVTKQQITAYKSLLKKLNILPIK----HIQITEKIDKIPDYIDQLVNQNHAYVSTQ 133
Query: 140 DGVYFEVQKFKDYGKLSGVKIEELRKGARVEPGEGKKNPEDFALWKKAKPGEPKWDSPWG 199
+ VYF V K YG L+ + E KKN DF LWK G KW+S WG
Sbjct: 134 NNVYFAVNSLKQYGYLANRMVH------LEETDTDKKNKLDFVLWKITTAGI-KWNSKWG 186
Query: 200 EGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIAQSEACFGHEWVRYWLHTGF 259
GRPGWH+EC+ + IHGGG DL FPHHENE A A + ++W+H G
Sbjct: 187 LGRPGWHVECAFLIDYCFKNELTIHGGGVDLKFPHHENENALHMALYNQPITKHWMHIGH 246
Query: 260 VMVKGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHYRSPLDYTEEGLQHAKNNLERL 319
+M++ +KMSKSL NF+ + L + V+R QKHY P+D + ++ A N+++R+
Sbjct: 247 LMIENQKMSKSLQNFLLAVDFLNFHDFRVLRWIFYQKHYLHPIDLNQSLIEKANNDIQRI 306
Query: 320 YNTLENIRIAMRNAELSYKWSEKDFEAYEAIREARKKFYDAMDDDFNTAEALKAVFEVSN 379
TL R + +E S S K ++ + A+ D+ N A A+ A++++
Sbjct: 307 AKTLNVARTWLVYSEQSELISPKQYD----------PVFSALLDNLNFANAVAAIWKLIK 356
Query: 380 AINKYILEVDKPKESILRKALEFFKVVSEVFGIFEDYFKEEKKGEEEKLIELLVEVRKQL 439
IN I D S+LR+ L F + ++ GI K KL L++ L
Sbjct: 357 KINTSIKTKD---FSVLREQLSFLEWSIDLLGI-------SFKSIHTKLNVRLIKEWSIL 406
Query: 440 RKEKRFDLADKIREELRK 457
K+K D AD+IR++L K
Sbjct: 407 HKQKAMDKADQIRKKLIK 424
>emb|CAC16398.1| (AJ276505) cysteinyl-tRNA-synthetase [Mus musculus domesticus]
Length = 831
Score = 249 bits (628), Expect = 7e-65
Identities = 151/432 (34%), Positives = 235/432 (53%), Gaps = 48/432 (11%)
Query: 88 KLAERFIKVFLEDMNALKVKPADIYPRVTEHIDDIIEFIKKLKEKGYAYEGSDGVYFEVQ 147
KL + + + F +DM AL V P D+ RV+E++ +I+ F++K+ + GY Y + VYF+
Sbjct: 297 KLPKFWEEEFHKDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYASNGSVYFDTA 356
Query: 148 KFK-----DYGKLSGVKIEELRKGARVEPGEG-----------KKNPEDFALWKKAKPGE 191
KF YGKL + + + ++ GEG K++P DFALWK +KPGE
Sbjct: 357 KFAASEKHSYGKLVPEAVGDQKA---LQEGEGDLSISADRLSEKRSPNDFALWKASKPGE 413
Query: 192 PKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIAQSEACFGHE-W 250
P W PWG+GRPGWHIECS M+ LG S DIHGGG DL FPHH+NE+AQSEA F ++ W
Sbjct: 414 PSWPCPWGKGRPGWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQSEAYFENDCW 473
Query: 251 VRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHYRSPLDYT----E 306
VRY+LHTG + + G KMSKSL NF+T+++ L+++S +RL L ++ LDY+ E
Sbjct: 474 VRYFLHTGHLTIAGCKMSKSLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSSNTME 533
Query: 307 EGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREARKKFYDAMDDDFN 366
LQ+ K E N + +R + KW ++ E + + ++A+ D+ +
Sbjct: 534 SALQYEKFMNEFFLNVKDILRAPVDITGQFEKWEAEEVELNKNFYGKKTAVHEALCDNID 593
Query: 367 TAEALKAVFEVSNAINKYI----LEVDKPKESILRKALEFFKVVSEVFGIFEDY----FK 418
T ++ + + + N Y+ E +P ++L + + ++FG E+ F
Sbjct: 594 TRTVMEEMRALVSQCNLYMAARKAERRRPNRALLENIAMYLTHMLKIFGAIEEESPLGFP 653
Query: 419 EEKKGEEEKL-------IELLVEVRKQLRKEKR-------FDLADKIREE-LRKLGIQLE 463
G L +++L E R+ +RK R L+D +R++ L +LG++ E
Sbjct: 654 VGGPGTNLNLESTVMPYLQVLSEFREGVRKIAREKKVLEVLQLSDALRDDILPELGVRFE 713
Query: 464 D-KGQETVWKRV 474
D +G TV K V
Sbjct: 714 DHEGLPTVVKLV 725
Score = 88.9 bits (217), Expect = 1e-16
Identities = 41/80 (51%), Positives = 58/80 (72%), Gaps = 1/80 (1%)
Query: 3 IKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYL-EHRGFT 61
+++YN+LTR K+ P +V Y CGPTVYD H+GHAR+YI+FD++RR L ++ +
Sbjct: 112 LRLYNSLTRNKDVFIPQDGKKVTWYCCGPTVYDASHMGHARSYISFDILRRVLRDYFQYD 171
Query: 62 VLMVMNFTDIDDKIIKRAQE 81
V MN TDIDDKII+RA++
Sbjct: 172 VFYCMNITDIDDKIIRRARQ 191
>emb|CAC16403.1| (AJ276796) CysRS protein [Mus musculus]
Length = 831
Score = 249 bits (628), Expect = 7e-65
Identities = 151/432 (34%), Positives = 235/432 (53%), Gaps = 48/432 (11%)
Query: 88 KLAERFIKVFLEDMNALKVKPADIYPRVTEHIDDIIEFIKKLKEKGYAYEGSDGVYFEVQ 147
KL + + + F +DM AL V P D+ RV+E++ +I+ F++K+ + GY Y + VYF+
Sbjct: 297 KLPKFWEEEFHKDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYASNGSVYFDTA 356
Query: 148 KFK-----DYGKLSGVKIEELRKGARVEPGEG-----------KKNPEDFALWKKAKPGE 191
KF YGKL + + + ++ GEG K++P DFALWK +KPGE
Sbjct: 357 KFAASEKHSYGKLVPEAVGDQKA---LQEGEGDLSISADRLSEKRSPNDFALWKASKPGE 413
Query: 192 PKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIAQSEACFGHE-W 250
P W PWG+GRPGWHIECS M+ LG S DIHGGG DL FPHH+NE+AQSEA F ++ W
Sbjct: 414 PSWPCPWGKGRPGWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQSEAYFENDCW 473
Query: 251 VRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHYRSPLDYT----E 306
VRY+LHTG + + G KMSKSL NF+T+++ L+++S +RL L ++ LDY+ E
Sbjct: 474 VRYFLHTGHLTIAGCKMSKSLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSSNTME 533
Query: 307 EGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREARKKFYDAMDDDFN 366
LQ+ K E N + +R + KW ++ E + + ++A+ D+ +
Sbjct: 534 SALQYEKFMNEFFLNVKDILRAPVDITGQFEKWEAEEVELNKNFYGKKTAVHEALCDNID 593
Query: 367 TAEALKAVFEVSNAINKYI----LEVDKPKESILRKALEFFKVVSEVFGIFEDY----FK 418
T ++ + + + N Y+ E +P ++L + + ++FG E+ F
Sbjct: 594 TRTVMEEMRALVSQCNLYMAARKAERRRPNRALLENIAMYLTHMLKIFGAIEEESPLGFP 653
Query: 419 EEKKGEEEKL-------IELLVEVRKQLRKEKR-------FDLADKIREE-LRKLGIQLE 463
G L +++L E R+ +RK R L+D +R++ L +LG++ E
Sbjct: 654 VGGPGTNLNLESTVMPYLQVLSEFREGVRKIAREKKVLEVLQLSDALRDDILPELGVRFE 713
Query: 464 D-KGQETVWKRV 474
D +G TV K V
Sbjct: 714 DHEGLPTVVKLV 725
Score = 88.9 bits (217), Expect = 1e-16
Identities = 41/80 (51%), Positives = 58/80 (72%), Gaps = 1/80 (1%)
Query: 3 IKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYL-EHRGFT 61
+++YN+LTR K+ P +V Y CGPTVYD H+GHAR+YI+FD++RR L ++ +
Sbjct: 112 LRLYNSLTRNKDVFIPQDGKKVTWYCCGPTVYDASHMGHARSYISFDILRRVLRDYFQYD 171
Query: 62 VLMVMNFTDIDDKIIKRAQE 81
V MN TDIDDKII+RA++
Sbjct: 172 VFYCMNITDIDDKIIRRARQ 191
>gi|10835051 cysteinyl-tRNA synthetase [Homo sapiens]
>gi|11440684|ref|XP_006485.1| cysteinyl-tRNA synthetase
[Homo sapiens] >gi|9837515|gb|AAG00578.1|AF288206_1
(AF288206) cytoplasmic cysteinyl-tRNA synthetase [Homo
sapiens]
Length = 748
Score = 246 bits (621), Expect = 5e-64
Identities = 149/420 (35%), Positives = 228/420 (53%), Gaps = 42/420 (10%)
Query: 97 FLEDMNALKVKPADIYPRVTEHIDDIIEFIKKLKEKGYAYEGSDGVYFEVQKFKDYGKLS 156
F DM AL V P D+ RV+E++ +I+ F++K+ + GY Y + VYF+ KF K S
Sbjct: 223 FHRDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYVSNGSVYFDTAKFASSEKHS 282
Query: 157 GVKI--EELRKGARVEPGEG-----------KKNPEDFALWKKAKPGEPKWDSPWGEGRP 203
K+ E + ++ GEG K++P DFALWK +KPGEP W PWG+GRP
Sbjct: 283 YGKLVPEAVGDQKALQEGEGDLSISADRLSEKRSPNDFALWKASKPGEPSWPCPWGKGRP 342
Query: 204 GWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIAQSEACFGHE-WVRYWLHTGFVMV 262
GWHIECS M+ LG S DIHGGG DL FPHH+NE+AQSEA F ++ WVRY+LHTG + +
Sbjct: 343 GWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQSEAYFENDCWVRYFLHTGHLTI 402
Query: 263 KGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHYRSPLDYT----EEGLQHAKNNLER 318
G KMSKSL NF+T+++ L+++S +RL L ++ LDY+ E LQ+ K E
Sbjct: 403 AGCKMSKSLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSSNTMESALQYEKFLNEF 462
Query: 319 LYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREARKKFYDAMDDDFNTAEALKAVFEVS 378
N + +R + KW E++ E + + + + A+ D+ +T ++ + +
Sbjct: 463 FLNVKDILRAPVDITGQFEKWGEEEAELNKNFYDKKTAIHKALCDNVDTRTVMEEMRALV 522
Query: 379 NAINKYILE----VDKPKESILRKALEFFKVVSEVFGIFED----YFKEEKKGEEEKL-- 428
+ N Y+ +P +++L + + ++FG E+ F G L
Sbjct: 523 SQCNLYMAARKAVRKRPNQALLENIALYLTHMLKIFGAVEEDSSLGFPVGGPGTSLSLEA 582
Query: 429 -----IELLVEVRKQLRKEKR-------FDLADKIREE-LRKLGIQLED-KGQETVWKRV 474
+++L E R+ +RK R L+D +R+ L +LG++ ED +G TV K V
Sbjct: 583 TVMPYLQVLSEFREGVRKIAREQKVPEILQLSDALRDNILPELGVRFEDHEGLPTVVKLV 642
Score = 91.3 bits (223), Expect = 2e-17
Identities = 44/80 (55%), Positives = 57/80 (71%), Gaps = 1/80 (1%)
Query: 3 IKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYL-EHRGFT 61
+ +YN+LTR KE P +V Y CGPTVYD H+GHAR+YI+FD++RR L ++ F
Sbjct: 29 LHLYNSLTRNKEVFIPQDGKKVTWYCCGPTVYDASHMGHARSYISFDILRRVLKDYFKFD 88
Query: 62 VLMVMNFTDIDDKIIKRAQE 81
V MN TDIDDKIIKRA++
Sbjct: 89 VFYCMNITDIDDKIIKRARQ 108
>gb|AAG00579.1|AF288207_1 (AF288207) cysteinyl-tRNA synthetase [Homo sapiens]
Length = 726
Score = 246 bits (621), Expect = 5e-64
Identities = 149/420 (35%), Positives = 228/420 (53%), Gaps = 42/420 (10%)
Query: 97 FLEDMNALKVKPADIYPRVTEHIDDIIEFIKKLKEKGYAYEGSDGVYFEVQKFKDYGKLS 156
F DM AL V P D+ RV+E++ +I+ F++K+ + GY Y + VYF+ KF K S
Sbjct: 223 FHRDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYVSNGSVYFDTAKFASSEKHS 282
Query: 157 GVKI--EELRKGARVEPGEG-----------KKNPEDFALWKKAKPGEPKWDSPWGEGRP 203
K+ E + ++ GEG K++P DFALWK +KPGEP W PWG+GRP
Sbjct: 283 YGKLVPEAVGDQKALQEGEGDLSISADRLSEKRSPNDFALWKASKPGEPSWPCPWGKGRP 342
Query: 204 GWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIAQSEACFGHE-WVRYWLHTGFVMV 262
GWHIECS M+ LG S DIHGGG DL FPHH+NE+AQSEA F ++ WVRY+LHTG + +
Sbjct: 343 GWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQSEAYFENDCWVRYFLHTGHLTI 402
Query: 263 KGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHYRSPLDYT----EEGLQHAKNNLER 318
G KMSKSL NF+T+++ L+++S +RL L ++ LDY+ E LQ+ K E
Sbjct: 403 AGCKMSKSLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSSNTMESALQYEKFLNEF 462
Query: 319 LYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREARKKFYDAMDDDFNTAEALKAVFEVS 378
N + +R + KW E++ E + + + + A+ D+ +T ++ + +
Sbjct: 463 FLNVKDILRAPVDITGQFEKWGEEEAELNKNFYDKKTAIHKALCDNVDTRTVMEEMRALV 522
Query: 379 NAINKYILE----VDKPKESILRKALEFFKVVSEVFGIFED----YFKEEKKGEEEKL-- 428
+ N Y+ +P +++L + + ++FG E+ F G L
Sbjct: 523 SQCNLYMAARKAVRKRPNQALLENIALYLTHMLKIFGAVEEDSSLGFPVGGPGTSLSLEA 582
Query: 429 -----IELLVEVRKQLRKEKR-------FDLADKIREE-LRKLGIQLED-KGQETVWKRV 474
+++L E R+ +RK R L+D +R+ L +LG++ ED +G TV K V
Sbjct: 583 TVMPYLQVLSEFREGVRKIAREQKVPEILQLSDALRDNILPELGVRFEDHEGLPTVVKLV 642
Score = 91.3 bits (223), Expect = 2e-17
Identities = 44/80 (55%), Positives = 57/80 (71%), Gaps = 1/80 (1%)
Query: 3 IKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYL-EHRGFT 61
+ +YN+LTR KE P +V Y CGPTVYD H+GHAR+YI+FD++RR L ++ F
Sbjct: 29 LHLYNSLTRNKEVFIPQDGKKVTWYCCGPTVYDASHMGHARSYISFDILRRVLKDYFKFD 88
Query: 62 VLMVMNFTDIDDKIIKRAQE 81
V MN TDIDDKIIKRA++
Sbjct: 89 VFYCMNITDIDDKIIKRARQ 108
>gb|AAG37230.1| (AF299082) cysteinyl-tRNA synthetase [Giardia intestinalis]
Length = 645
Score = 245 bits (618), Expect = 1e-63
Identities = 178/537 (33%), Positives = 261/537 (48%), Gaps = 71/537 (13%)
Query: 7 NTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLE-HRGFTVLMV 65
N+LT + EEL+ V Y+CGPTVYD HLGHARTY+ FDV+RR LE + G V
Sbjct: 12 NSLTGRLEELRTHAPSTVLAYICGPTVYDSTHLGHARTYVTFDVVRRILEDYFGLRVRYQ 71
Query: 66 MNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHIDDIIEF 125
N TD+DDKII RA E G + ++ + FL DM+ L V+P + RVTE++ DII F
Sbjct: 72 CNITDVDDKIIARAVERGSSIFDICRKYEQEFLSDMHTLSVRPFTVVTRVTEYMADIILF 131
Query: 126 IKKLKEKGYAYEGSDGVYFEVQKFK----DYGKLS--GVKIEELRKGARVEPGEGKKN-- 177
I+K+ + G+AY + VYF+V + Y KL G +EL+ + G KN
Sbjct: 132 IQKIMDNGFAYVSAGSVYFDVAAARSAGYSYPKLRPLGSSSDELQLLIQNADGMDSKNRV 191
Query: 178 -----PEDFALWKKAKPGEP---KWDSPWGE------------GRPGWHIECSVMSSKYL 217
DFALWK K EP KWD+ + GRPGWHIECS M++ L
Sbjct: 192 SEKRSASDFALWKAWKETEPEDAKWDATFSHKNGAVSELITLPGRPGWHIECSAMAAAVL 251
Query: 218 GE----SFDIHGGGNDLIFPHHENEIAQSEACFGHE-WVRYWLHTGFVMVKGEKMSKSLG 272
G+ +FD+H GG DL FPHH+NE+ Q E G + + +LH+G + + G+ MSKS
Sbjct: 252 GKDTGGAFDLHLGGCDLQFPHHDNELIQLETWAGKKNMIGCFLHSGHLKIAGDVMSKSKK 311
Query: 273 NFVTVRELLQRYSPEVIRLFVLQKHYRSPLDYTEEGLQHAKNNLERLYNTLENIRIAMRN 332
NF TVRE+L ++ +R+ Y + LDY+ + A +++ + L N R +++
Sbjct: 312 NFKTVREILSIFTANQVRMLFCMVPYSASLDYSISMMDAAVAKDKKITSFLSNCRQIIQH 371
Query: 333 AE--------LSYKWSEKDFEAYEAIREARKKFYDAMDDDFNTAEALKAVFEVSNAINKY 384
E L Y +E+ EA E A +D N A+ V + + Y
Sbjct: 372 EEELSEPIKNLRYSTTEEALEAQTI--EFLSNVDTAFRNDINIVSAMSHVMLLIDNCKAY 429
Query: 385 IL----EVDKPKESILRKALEFFKVVSEVFGIFEDYFKEEKKGEEEKL--IELLVEVRKQ 438
I E + +L A + V + G Y + E E L ++ R++
Sbjct: 430 IFACQTEGRQVSTFLLSNARDKIVHVLSIMGF--SYARGETSTAENALQVARVVCNFRRE 487
Query: 439 LR------------------KEKRFDLADKIREE-LRKLGIQLEDKGQETVWKRVKV 476
++ K+ L D++R+E L G +ED +E+ K + V
Sbjct: 488 IKDLLMASTTNTAETDTKTLKKMLLGLCDRLRDEHLPLTGFAIEDADKESYIKPINV 544
>sp|P75423|SYC_MYCPN CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LIGASE) (CYSRS)
>gi|2146088|pir||S73806 cysteine--tRNA ligase (EC
6.1.1.16) cysS - Mycoplasma pneumoniae (strain ATCC
29342) >gi|1674171|gb|AAB96128.1| (AE000047)
cysteinyl-tRNA synthetase [Mycoplasma pneumoniae]
Length = 437
Score = 243 bits (613), Expect = 4e-63
Identities = 152/446 (34%), Positives = 234/446 (52%), Gaps = 34/446 (7%)
Query: 19 LRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGFTVLMVMNFTDIDDKIIKR 78
L ++ +Y+CGPTVY+ HLG+ R I FDV++R L+ + V V N TDIDDKIIK
Sbjct: 21 LEQKQINIYLCGPTVYNDLHLGNTRPLIVFDVLQRVLQAAQYKVQFVQNITDIDDKIIKI 80
Query: 79 AQETGEDPGKLAERFI---KVFLEDMNALKVKPADIYPRVTEHIDDIIEFIKKLKEKGYA 135
AQ+ +L ++ I K L+ +N L +K + +VT+ ID + +I +L +KG+A
Sbjct: 81 AQQQEISEAQLCKQQITAYKSLLKKLNILPIK----HLQVTDKIDKMPGYIARLVKKGFA 136
Query: 136 YEGSDG-VYFEVQKFKDYGKLSGVKIEELRKGARVEPGEGKKNPEDFALWKKAKPGEPKW 194
Y G YF V + YG L+ +E + A K+N DF LWK+ G KW
Sbjct: 137 YVSPLGNTYFSVSQLPQYGILANRVVETIEDEAT-----DKRNKLDFVLWKQTTAGV-KW 190
Query: 195 DSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIAQSEACFGHEWVRYW 254
+SPWG GRPGWH+EC+ + + IHGGG DL FPHHENE A A + ++W
Sbjct: 191 NSPWGWGRPGWHVECAFLIDYSFKDQLTIHGGGVDLKFPHHENENAMHMALYDKPLTQHW 250
Query: 255 LHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHYRSPLDYTEEGLQHAKN 314
+H G +M + +KMSKSL NF+ + L + ++R QKHY PLD ++ ++ A +
Sbjct: 251 MHIGHLMFENQKMSKSLQNFLLAVDFLTIHDFRILRWLFYQKHYYHPLDLSQSLIEQACS 310
Query: 315 NLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREARKKFYDAMDDDFNTAEALKAV 374
+++R+ + R +E S + K FE + A+ ++ N A A+ +
Sbjct: 311 DIKRIQKAVNVCRTWFVYSEQSAIPAPKQFE----------PVFKALLNNLNFANAITHI 360
Query: 375 FEVSNAINKYILEVDKPKESILRKALEFFKVVSEVFGIFEDYFKEEKKGEEEKLIELLVE 434
+++ IN +V K S L++ L + + GI K KL L++
Sbjct: 361 WKLVKQINH---DVSKQNLSGLKEHLSHLEWALNILGI-------GFKSIHTKLNVQLIK 410
Query: 435 VRKQLRKEKRFDLADKIREELRKLGI 460
LRK + D AD++R++L K G+
Sbjct: 411 KWASLRKNGQLDKADEVRQKLIKKGL 436
>gi|6324082 Ynl247wp [Saccharomyces cerevisiae]
>gi|1730840|sp|P53852|YNY7_YEAST PUTATIVE CYSTEINYL-TRNA
SYNTHETASE C29E6.06C (CYSTEINE--TRNA LIGASE) (CYSRS)
>gi|2132775|pir||S63220 probable membrane protein
YNL247w - yeast (Saccharomyces cerevisiae)
>gi|1255971|emb|CAA65497.1| (X96722) ORF N0885
[Saccharomyces cerevisiae] >gi|1302287|emb|CAA96154.1|
(Z71523) ORF YNL247w [Saccharomyces cerevisiae]
Length = 767
Score = 242 bits (611), Expect = 7e-63
Identities = 128/306 (41%), Positives = 183/306 (58%), Gaps = 17/306 (5%)
Query: 97 FLEDMNALKVKPADIYPRVTEHIDDIIEFIKKLKEKGYAYEGSDG-VYFEVQKFKDYGKL 155
F +DM +L V P + RV+E++ +II+F++K+ + GYAY SDG VYF+ KF
Sbjct: 245 FNDDMLSLNVLPPTVTTRVSEYVPEIIDFVQKIIDNGYAYATSDGSVYFDTLKFDKSPNH 304
Query: 156 SGVKIEELRKGAR--VEPGEG---------KKNPEDFALWKKAKPGEPKWDSPWGEGRPG 204
K + KG + GEG KK+ DFALWK +K GEP+W+SPWG+GRPG
Sbjct: 305 DYAKCQPWNKGQLDLINDGEGSLSNFADNGKKSNNDFALWKASKAGEPEWESPWGKGRPG 364
Query: 205 WHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIAQSEACF-GHEWVRYWLHTGFVMVK 263
WHIECSVM+S LG + DIH GG DL FPHH+NE+AQSEA F +W+ Y+LHTG + ++
Sbjct: 365 WHIECSVMASDILGSNIDIHSGGIDLAFPHHDNELAQSEARFDNQQWINYFLHTGHLHIE 424
Query: 264 GEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHYRSPLDYTEEGLQHAKNNLERLYNTL 323
G+KMSKSL NF+T++E L+++SP +RL + + LD+ E + K+ + N
Sbjct: 425 GQKMSKSLKNFITIQEALKKFSPRQLRLAFASVQWNNQLDFKESLIHEVKSFENSMNNFF 484
Query: 324 ENIRIAMRNA----ELSYKWSEKDFEAYEAIREARKKFYDAMDDDFNTAEALKAVFEVSN 379
+ IR +A +S K+S + E E+ K + A D+ +T ALK + E+
Sbjct: 485 KTIRALKNDAASAGHISKKFSPLEKELLADFVESESKVHSAFCDNLSTPVALKTLSELVT 544
Query: 380 AINKYI 385
N YI
Sbjct: 545 KSNTYI 550
Score = 82.3 bits (200), Expect = 1e-14
Identities = 50/112 (44%), Positives = 65/112 (57%), Gaps = 10/112 (8%)
Query: 3 IKVYNTLTRKKEELKPLRDGE-VRMYVCGPTVYDYPHLGHARTYIAFDVIRRYL-EHRGF 60
+K+YN+LTR K E P V Y CGPTVYD H+GHAR Y++ D+ RR + ++ G+
Sbjct: 36 LKLYNSLTRSKVEFIPQSGNRGVTWYSCGPTVYDASHMGHARNYVSIDINRRIIQDYFGY 95
Query: 61 TVLMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNAL---KVKPA 109
V V N TDIDDKII RA++ L + F+K NA KVK A
Sbjct: 96 DVQFVQNVTDIDDKIILRARQ-----NYLFDNFVKENDTKFNATVVDKVKTA 142
>gb|AAC64633.1| (AF077541) contains similarity to class-I aminoacyl-tRNA
synthetases [Caenorhabditis elegans]
Length = 909
Score = 240 bits (607), Expect = 2e-62
Identities = 155/442 (35%), Positives = 231/442 (52%), Gaps = 56/442 (12%)
Query: 89 LAERFIKVFLEDMNALKVKPADIYPRVTEHIDDIIEFIKKLKEKGYAYEGSDG-VYFEVQ 147
LA+ + K FL DM L V P D+ RV+E++ ++I ++KK+ GYAY DG VYF+ +
Sbjct: 371 LAKTYEKEFLADMARLNVLPVDVLTRVSEYVPEVITYVKKIISNGYAYAAEDGSVYFDTK 430
Query: 148 KFKD-----YGKLS----GVKIEELRKGARVEPGE---------GKKNPEDFALWKKAKP 189
F+ Y KL G E+L K + GE K++P DFALWK +K
Sbjct: 431 AFEQNPKHFYAKLVPEAYGEDSEQLLKNMKESEGELSMSDDRLKSKRSPNDFALWKSSKD 490
Query: 190 GEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIAQSEACFGH- 248
GEP W S WG GRPGWHIECSVMSS G DIH GG DL FPHH+NEIAQ EA +
Sbjct: 491 GEPFWPSEWGNGRPGWHIECSVMSSAICGSKLDIHAGGFDLKFPHHDNEIAQVEAHYDDP 550
Query: 249 EWVRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHYRSPLDYT--- 305
WV Y+LH G + ++G KMSKSL NF+T+R+ L+ Y+P +RL L ++ LDY+
Sbjct: 551 HWVNYFLHCGTLRIQGMKMSKSLKNFITIRKALEDYTPRQLRLLFLMHNWADVLDYSSST 610
Query: 306 -EEGLQHAKNNLERLYNTLENIRIAMR--NAELSYKWSEKDFEAYEAIREARKKFYDAMD 362
E LQ K E + +R + +E K+ K+ + E + + + ++A+
Sbjct: 611 MERALQFEKITNEFFLLVKDFLRRHYKPDRSEGYQKFQGKELKLMEEFGKLKSEVHEALC 670
Query: 363 DDFNTAEALKAVFEVSNAINKYILEVDK----PKESILRKALEFFKVVSEVFGIFEDYFK 418
D +T ++ E+ + N YI+E +K P +LR + + ++FG +
Sbjct: 671 DSVDTRSVIEKFRELISLGNAYIVEKEKEGHVPNCLLLRNIAAYITNLLKIFGAIPQSNQ 730
Query: 419 E-------EKKGE-------EEKLIELLVEVRKQLRKEKR-----------FDLADKIRE 453
E E GE +E ++ ++ Q R++ R + D +R+
Sbjct: 731 EIGFVSEDECNGEGASTSFNKEAVVMPYLDALAQFREKVRLIAKEHKVNGILEECDTLRD 790
Query: 454 E-LRKLGIQLEDKGQETVWKRV 474
+ L +LG++LED+ +TV K V
Sbjct: 791 KTLTELGVRLEDRNGQTVVKLV 812
Score = 97.1 bits (238), Expect = 4e-19
Identities = 55/164 (33%), Positives = 90/164 (54%), Gaps = 30/164 (18%)
Query: 3 IKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRR-YLEHRGFT 61
+ VYN+LTR+KE P VR Y+CGPTVYD H+GHAR+Y++ D++RR + ++ G+
Sbjct: 184 LTVYNSLTRQKEVFVPNEGKRVRWYICGPTVYDSSHMGHARSYLSLDILRRVFRDYFGYD 243
Query: 62 VLMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHIDD 121
V +MN TD+DDKIIKRA+++ +K + + A P V + +D
Sbjct: 244 VEFIMNITDVDDKIIKRARQS---------HLLKSYFNESQA---------PPVMKVCED 285
Query: 122 IIEFIKKLKEKGYAYEGSDGVYFEVQKFKDYGKLSGVKIEELRK 165
++ ++ K K FE + D K+ V I+++++
Sbjct: 286 VVAALEHFKTK-----------FETEMDPDKKKMFEVMIKKVQQ 318
>gb|AAG03366.1| (AF024666) CysS [Corynebacterium striatum]
Length = 404
Score = 240 bits (605), Expect = 4e-62
Identities = 146/392 (37%), Positives = 209/392 (53%), Gaps = 27/392 (6%)
Query: 3 IKVYNTLTRKKEELK--PLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGF 60
+K+++T ++ +E+ P +GEV MYVCG T YD HLGHA TY+ FD+ +R L G
Sbjct: 19 LKLFDTADQRVKEVDTTPDANGEVGMYVCGITPYDSTHLGHAATYLTFDLAQRQLLANGH 78
Query: 61 TVLMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHID 120
V V N TD+DD + +RA+ G D +L I +F DM L V P Y E +D
Sbjct: 79 KVHYVQNITDVDDPLFERAERDGVDWRELGTSQINLFRSDMEILSVIPPCDYIGAMESVD 138
Query: 121 DIIEFIKKLKEKGYAYEGSDG-VYFEVQKFKDYG---KLSGVKIEELRKGARVEPG-EGK 175
++I +++L + G AYE G +Y + + +G L +EE +P EGK
Sbjct: 139 EVIAMVQQLLDAGAAYELDQGDIYASIDATEQFGYESNLDRATMEEYFAERGGDPDREGK 198
Query: 176 KNPEDFALWKKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHH 235
++P D +W+ + GEP WDSP+G GRPGWH+ECS +++ LG F I GGG+DL FPHH
Sbjct: 199 RDPLDALVWRGHREGEPAWDSPFGPGRPGWHVECSAIATNRLGSHFAIQGGGSDLAFPHH 258
Query: 236 ENEIAQSEACFGHE-WVRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQR-YSPEVIRLFV 293
E A +EA E +++H G + + G KMSKSLGN V V +L + + P IRL V
Sbjct: 259 EFSAAHAEAALKVERMAGHYVHAGMIALDGVKMSKSLGNLVFVHKLSEAGHDPSAIRLAV 318
Query: 294 LQKHYRSPLDYTEEGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREA 353
HYR D+++ L A+ L R L E+S + EA E + +
Sbjct: 319 FAGHYREDRDFSDAILAEAEERLTRWREQLA--------GEVS------EAEATEVVDKL 364
Query: 354 RKKFYDAMDDDFNTAEALKAVFEVSNAINKYI 385
R + DD NT EAL + + N+ I
Sbjct: 365 RA----ILADDLNTPEALSLLDGAAGDCNQII 392
>gb|AAA73901.1| (L06845) cysteinyl-tRNA synthetase [Homo sapiens]
Length = 595
Score = 239 bits (604), Expect = 5e-62
Identities = 127/341 (37%), Positives = 194/341 (56%), Gaps = 22/341 (6%)
Query: 97 FLEDMNALKVKPADIYPRVTEHIDDIIEFIKKLKEKGYAYEGSDGVYFEVQKFKDYGKLS 156
F DM AL V P D+ RV+E++ +I+ F++K+ + GY Y + VYF+ KF K S
Sbjct: 180 FHRDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYVSNGSVYFDTAKFASSEKHS 239
Query: 157 GVKI--EELRKGARVEPGEG-----------KKNPEDFALWKKAKPGEPKWDSPWGEGRP 203
K+ E + ++ GEG K++P DFALWK +KPGEP W PWG+GRP
Sbjct: 240 YGKLVPEAVGDQKALQEGEGDLSISADRLSEKRSPNDFALWKASKPGEPSWPCPWGKGRP 299
Query: 204 GWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIAQSEACFGHE-WVRYWLHTGFVMV 262
GWHIECS M+ LG S DIHGGG DL FPHH+NE+AQSEA F ++ WVRY+LHTG + +
Sbjct: 300 GWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQSEAYFENDCWVRYFLHTGHLTI 359
Query: 263 KGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHYRSPLDYT----EEGLQHAKNNLER 318
G KMSKSL NF+T+++ L+++S +RL L ++ LDY+ E LQ+ K E
Sbjct: 360 AGCKMSKSLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSSNTMESALQYEKFLNEF 419
Query: 319 LYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREARKKFYDAMDDDFNTAEALKAVFEVS 378
N + +R + KW E++ E + + + + A+ D+ +T ++ + +
Sbjct: 420 FLNVKDILRAPVDITGQFEKWGEEEAELNKNFYDKKTAIHKALCDNVDTRTVMEEMRALV 479
Query: 379 NAINKYILE----VDKPKESILRKALEFFKVVSEVFGIFED 415
+ N Y+ +P +++L + + ++FG E+
Sbjct: 480 SQCNLYMAARKAVRKRPNQALLENIALYLTHMLKIFGAVEE 520
Score = 78.0 bits (189), Expect = 2e-13
Identities = 38/64 (59%), Positives = 49/64 (76%), Gaps = 2/64 (3%)
Query: 20 RDGE-VRMYVCGPTVYDYPHLGHARTYIAFDVIRRYL-EHRGFTVLMVMNFTDIDDKIIK 77
+DG+ V Y CGPTVYD H+GHAR+YI+FD++RR L ++ F V MN TDIDDKIIK
Sbjct: 2 QDGKKVTWYCCGPTVYDASHMGHARSYISFDILRRVLKDYFKFDVFYCMNITDIDDKIIK 61
Query: 78 RAQE 81
RA++
Sbjct: 62 RARQ 65
>sp|P49589|SYC_HUMAN CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LIGASE) (CYSRS)
Length = 638
Score = 239 bits (604), Expect = 5e-62
Identities = 127/341 (37%), Positives = 194/341 (56%), Gaps = 22/341 (6%)
Query: 97 FLEDMNALKVKPADIYPRVTEHIDDIIEFIKKLKEKGYAYEGSDGVYFEVQKFKDYGKLS 156
F DM AL V P D+ RV+E++ +I+ F++K+ + GY Y + VYF+ KF K S
Sbjct: 223 FHRDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYVSNGSVYFDTAKFASSEKHS 282
Query: 157 GVKI--EELRKGARVEPGEG-----------KKNPEDFALWKKAKPGEPKWDSPWGEGRP 203
K+ E + ++ GEG K++P DFALWK +KPGEP W PWG+GRP
Sbjct: 283 YGKLVPEAVGDQKALQEGEGDLSISADRLSEKRSPNDFALWKASKPGEPSWPCPWGKGRP 342
Query: 204 GWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIAQSEACFGHE-WVRYWLHTGFVMV 262
GWHIECS M+ LG S DIHGGG DL FPHH+NE+AQSEA F ++ WVRY+LHTG + +
Sbjct: 343 GWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQSEAYFENDCWVRYFLHTGHLTI 402
Query: 263 KGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHYRSPLDYT----EEGLQHAKNNLER 318
G KMSKSL NF+T+++ L+++S +RL L ++ LDY+ E LQ+ K E
Sbjct: 403 AGCKMSKSLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSSNTMESALQYEKFLNEF 462
Query: 319 LYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREARKKFYDAMDDDFNTAEALKAVFEVS 378
N + +R + KW E++ E + + + + A+ D+ +T ++ + +
Sbjct: 463 FLNVKDILRAPVDITGQFEKWGEEEAELNKNFYDKKTAIHKALCDNVDTRTVMEEMRALV 522
Query: 379 NAINKYILE----VDKPKESILRKALEFFKVVSEVFGIFED 415
+ N Y+ +P +++L + + ++FG E+
Sbjct: 523 SQCNLYMAARKAVRKRPNQALLENIALYLTHMLKIFGAVEE 563
Score = 91.3 bits (223), Expect = 2e-17
Identities = 44/80 (55%), Positives = 57/80 (71%), Gaps = 1/80 (1%)
Query: 3 IKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYL-EHRGFT 61
+ +YN+LTR KE P +V Y CGPTVYD H+GHAR+YI+FD++RR L ++ F
Sbjct: 29 LHLYNSLTRNKEVFIPQDGKKVTWYCCGPTVYDASHMGHARSYISFDILRRVLKDYFKFD 88
Query: 62 VLMVMNFTDIDDKIIKRAQE 81
V MN TDIDDKIIKRA++
Sbjct: 89 VFYCMNITDIDDKIIKRARQ 108
>emb|CAA67901.1| (X99587) cysteine tRNA synthetase [Azospirillum brasilense]
Length = 448
Score = 239 bits (604), Expect = 5e-62
Identities = 171/478 (35%), Positives = 228/478 (46%), Gaps = 36/478 (7%)
Query: 1 MGIKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGF 60
M + +YNTLTR+KE +P+ V MYVCGPTVYD H+G+AR + FD++ R L
Sbjct: 1 MPLDLYNTLTRRKERFEPMTPDRVGMYVCGPTVYDTAHIGNARP-VVFDLLFRLLRRLYP 59
Query: 61 TVLMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHID 120
V V N T DDKII R TG D G A++ + L + I PR T HI
Sbjct: 60 AVTYVRNITASDDKIIDRRATTGADRG--ADQAHRGPLPRRHGPLNAAPTIEPRATHHIS 117
Query: 121 DIIEFIKKLKEKGYAYEGSDGVYFEVQKFKDYGKLSGVKIEELRKGARVEPGEGKKNPED 180
++ I L E ++++ G+LS ++E+ GARVE K++ D
Sbjct: 118 HMVALIGLLIEPATPTPRKGTCCSPCRRWRSTGQLSRRSLDEMIAGARVEVAPYKRDSSD 177
Query: 181 FALWKKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIA 240
F LWK + G+P WDSPWG GRPGWHIECS M+ ++LG +FDIHGGG DLI P HENEIA
Sbjct: 178 FVLWKPSTDGQPGWDSPWGRGRPGWHIECSAMAKEHLGVTFDIHGGGLDLILPDHENEIA 237
Query: 241 QSE-ACFGHEWVRYWLHTGFVMVKG-EKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHY 298
QS A G W GFV V+G E F T P H
Sbjct: 238 QSRCAHAGSRWPATGSTNGFVTVEGREGCPSRWATFFTGGTSCWTEFPG-------GGHP 290
Query: 299 RSPLDYTEEGL---QHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREARK 355
Y GL + +K L+R Y L A AEL +
Sbjct: 291 LGVRPYRSRGLPEAEESKATLDRWYQALRG-DPAPAQAELPF------------------ 331
Query: 356 KFYDAMDDDFNTAEALKAVFEVSNAINKYILEVDKPKESILRKALEFFKVVSEVFGIFED 415
A++DD N+ A+ + E+++A+NK E +K ++ E + E +
Sbjct: 332 DVLAALEDDLNSPLAISHLHELASAVNKATGEAEKAAAKGRCRSAERW-AAPETRSVV-P 389
Query: 416 YFKEEKKGEEEKLIELLVEVRKQLRKEKRFDLADKIREELRKLGIQLEDKGQETVWKR 473
E + I+ +E R RK K + AD+IR+EL LGI LED Q T WKR
Sbjct: 390 LGAEGAAALSDADIQQRIEDRSAARKAKNYAEADRIRKELADLGIVLEDGPQGTTWKR 447
>gb|AAD34748.1| (AF132160) unknown [Drosophila melanogaster]
>gi|7302987|gb|AAF58057.1| (AE003808) BcDNA:LD21177 gene
product [Drosophila melanogaster]
Length = 741
Score = 236 bits (595), Expect = 5e-61
Identities = 149/415 (35%), Positives = 219/415 (51%), Gaps = 47/415 (11%)
Query: 97 FLEDMNALKVKPADIYPRVTEHIDDIIEFIKKLKEKGYAYEGSDGVYFEVQKFKDYGKLS 156
F DM +L + P D+ RV+E++ I+ FI+K+ + G AY ++ VYF+V F K
Sbjct: 215 FHNDMKSLNILPPDVLTRVSEYVPQIVTFIQKIIDNGLAYAANNSVYFDVNGFDKREKHH 274
Query: 157 GVKI--EELRKGARVEPGEG-----------KKNPEDFALWKKAKPGEPKWDSPWGEGRP 203
K+ E ++ GEG K++ DFALWK +K GEP WDSPWG+GRP
Sbjct: 275 YAKLVPEAYGDTKSLQEGEGDLSIAEDRLSEKRSANDFALWKASKAGEPWWDSPWGKGRP 334
Query: 204 GWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIAQSEACFGH-EWVRYWLHTGFVMV 262
GWHIECS M+S G +FDIH GG DL FPHH+NE+AQSEA F EWV+Y+LHTG + +
Sbjct: 335 GWHIECSAMASDIFGPTFDIHTGGVDLKFPHHDNELAQSEAAFNESEWVKYFLHTGHLTI 394
Query: 263 KGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHYRSPLDYTEEGLQHAKNNLERLYNT 322
G KMSKSL NFVT++E L+++S +RL L ++ LDY+E ++ A + L
Sbjct: 395 AGCKMSKSLKNFVTIQEALKKHSATQLRLAFLLHSWKDTLDYSENTMEMATQYEKFLNEF 454
Query: 323 LENIRIAMRNAELSYK-------WSEKDFEAYEAIREARKKFYDAMDDDFNTAEALKAVF 375
N++ R+ LS + W+E + + A+ + + ++ D+ +T AL A+
Sbjct: 455 FLNVKDLTRHV-LSEEPRRQFDAWTEVEAALQKKFSNAQVQVHASLCDNIDTRSALDAIR 513
Query: 376 EVSNAINKYILEVDKPKES-ILRKALEFFKVVSEVFGIFE------DYFKEEKKGEE--- 425
E+ + N YI + S +LR + + VFG + G +
Sbjct: 514 ELVSVSNVYIRDNKTRLNSLLLRNVATYITDLLHVFGAISGPRGGIGFPVSGGSGAQAAG 573
Query: 426 -----------EKLIELLVEVRKQLRKEKRFD---LADKIREE-LRKLGIQLEDK 465
+ L E VR+Q + K FD L D +R+ L LG++LEDK
Sbjct: 574 ADLETTVLPYVQSLAEFRYLVREQAKTLKAFDILKLCDDLRDNVLPNLGVRLEDK 628
Score = 98.3 bits (241), Expect = 2e-19
Identities = 44/80 (55%), Positives = 62/80 (77%), Gaps = 1/80 (1%)
Query: 3 IKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYL-EHRGFT 61
+K++N+LTR+KE+ PL V Y CGPTVYD H+GHAR+YI+FD++RR L ++ G+
Sbjct: 20 LKLFNSLTRQKEDFVPLDGNNVTWYSCGPTVYDASHMGHARSYISFDILRRILSDYFGYN 79
Query: 62 VLMVMNFTDIDDKIIKRAQE 81
+ VMN TDIDDKII+RA++
Sbjct: 80 IHYVMNITDIDDKIIRRARQ 99
>dbj|BAA29032.1| (AB015589) cysteinyl-tRNA synthetase [Mus musculus]
Length = 486
Score = 232 bits (585), Expect = 8e-60
Identities = 122/319 (38%), Positives = 185/319 (57%), Gaps = 24/319 (7%)
Query: 88 KLAERFIKVFLEDMNALKVKPADIYPRVTEHIDDIIEFIKKLKEKGYAYEGSDGVYFEVQ 147
KL + + + F +DM A V P D+ RV+E++ +I+ F++K+ + GY Y + VYF+
Sbjct: 169 KLPKFWEEEFHKDMEAPNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYASNGSVYFDTA 228
Query: 148 KFK-----DYGKLSGVKIEELRKGARVEPGEG-----------KKNPEDFALWKKAKPGE 191
KF YGKL + + + ++ GEG K++P DFALWK +KPGE
Sbjct: 229 KFAASEKHSYGKLVPEAVGDQKA---LQEGEGDLSISADRLSEKRSPNDFALWKASKPGE 285
Query: 192 PKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIAQSEACFGHE-W 250
P W PWG+GRPGWHIECS M+ LG S DIHGGG DL FPHH+NE+AQSEA F ++ W
Sbjct: 286 PSWPCPWGKGRPGWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQSEAYFENDCW 345
Query: 251 VRYWLHTGFVMVKGEKMSKSLGNFVTVRELLQRYSPEVIRLFVLQKHYRSPLDYT----E 306
VRY+LHTG + + G KMSKSL NF+T+++ L+++S +RL L ++ LDY+ E
Sbjct: 346 VRYFLHTGHLTIAGCKMSKSLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSSNTME 405
Query: 307 EGLQHAKNNLERLYNTLENIRIAMRNAELSYKWSEKDFEAYEAIREARKKFYDAMDDDFN 366
LQ+ K E N + +R + KW ++ E + + ++A+ D+ +
Sbjct: 406 SALQYEKFMNEFFLNVKDILRAPVDITGQFEKWEAEEVELNKNFYGKKTAVHEALCDNID 465
Query: 367 TAEALKAVFEVSNAINKYI 385
T ++ + + + N Y+
Sbjct: 466 TRTVMEEMRALVSQCNLYM 484
Score = 75.3 bits (182), Expect = 1e-12
Identities = 34/60 (56%), Positives = 46/60 (76%), Gaps = 1/60 (1%)
Query: 23 EVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYL-EHRGFTVLMVMNFTDIDDKIIKRAQE 81
+V Y CGPTVYD H+GHAR+YI+FD++RR L ++ + V MN TDIDDKII+RA++
Sbjct: 4 KVTWYCCGPTVYDASHMGHARSYISFDILRRVLRDYFQYDVFYCMNITDIDDKIIRRARQ 63
>sp|O33264|SYC2_MYCTU CYSTEINYL-TRNA SYNTHETASE 2 (CYSTEINE--TRNA LIGASE 2) (CYSRS 2)
>gi|7477957|pir||E70514 probable cysS2 - Mycobacterium
tuberculosis (strain H37RV) >gi|3261823|emb|CAB10724.1|
(Z97559) cysS2 [Mycobacterium tuberculosis]
Length = 414
Score = 224 bits (565), Expect = 2e-57
Identities = 127/329 (38%), Positives = 178/329 (53%), Gaps = 16/329 (4%)
Query: 3 IKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGFTV 62
+++Y++ R+ + P + MYVCG T YD HLGHA TY+ FD+I R G +
Sbjct: 19 LRLYDSADRQVRPVAP--GSKATMYVCGITPYDATHLGHAATYVTFDLIHRLWLDLGHEL 76
Query: 63 LMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHIDDI 122
V N TDIDD + +RA G D LA+ + +F EDM AL+V P Y TE I ++
Sbjct: 77 HYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRVLPPQDYVGATEAIAEM 136
Query: 123 IEFIKKLKEKGYAY-------EGSDGVYFEVQKFKDYGKLSGVKIEELRKGARVEPGE-- 173
+E I+K+ G AY E D +YF +G SG + + + G+
Sbjct: 137 VELIEKMLACGAAYVIDREMGEYQD-IYFRADATLQFGYESGYDRDTMLRLCEERGGDPR 195
Query: 174 --GKKNPEDFALWKKAKPGEPKWDSPWGEGRPGWHIECSVMSSKYLGESFDIHGGGNDLI 231
GK + D LW+ A+PGEP W SP+G GRPGWH+EC+ ++ +G DI GGG+DLI
Sbjct: 196 RPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSRIGSGLDIQGGGSDLI 255
Query: 232 FPHHENEIAQSEACFG-HEWVRYWLHTGFVMVKGEKMSKSLGNFVTVREL-LQRYSPEVI 289
FPHHE A +E G + R+++H G + G KMSKS GN V V L Q P +
Sbjct: 256 FPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLVLVSALRAQDVEPSAV 315
Query: 290 RLFVLQKHYRSPLDYTEEGLQHAKNNLER 318
RL +L HYR+ ++++ L A L R
Sbjct: 316 RLGLLAGHYRADRFWSQQVLDEATARLHR 344
>sp|Q49784|SYC2_MYCLE CYSTEINYL-TRNA SYNTHETASE 2 (CYSTEINE--TRNA LIGASE 2) (CYSRS 2)
Length = 419
Score = 213 bits (537), Expect = 3e-54
Identities = 123/309 (39%), Positives = 163/309 (51%), Gaps = 16/309 (5%)
Query: 26 MYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGFTVLMVMNFTDIDDKIIKRAQETGED 85
MYVCG T YD HLGHA TY+AFD+I R G V V N TD+DD + +RA G D
Sbjct: 41 MYVCGITPYDATHLGHAATYLAFDLIHRLWLDLGHEVHYVQNVTDVDDPLFERADRNGVD 100
Query: 86 PGKLAERFIKVFLEDMNALKVKPADIYPRVTEHIDDIIEFIKKLKEKGYAYEGSD---GV 142
LAER + +F +DM +L++ P Y TE I +I+E + K+ G AY D +
Sbjct: 101 WRDLAEREVALFRDDMASLRILPPHDYVAATETIVEIVELVDKMLVSGAAYVIDDEYPDI 160
Query: 143 YFEVQKFKDYGKLSGVKIEELRKGARVEPGE----GKKNPEDFALWKKAKPGEPKWDSPW 198
YF +G SG + + + G+ GK D LW+ A+PGEP W SP+
Sbjct: 161 YFRADATLQFGYESGYDRDTMLRLYEQSGGDPRRPGKNGELDALLWRAARPGEPSWSSPF 220
Query: 199 GEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIAQSEACFGHEWV------- 251
G GRPGWH+EC+ ++ +G DI GGG+DLIFPHHE A +E G
Sbjct: 221 GPGRPGWHVECAAIALSRIGIGLDIQGGGSDLIFPHHEFTAAHAECVRGERRFAGTTCTL 280
Query: 252 -RYWLHTGFVMVKGEKMSKSLGNFVTVRELL-QRYSPEVIRLFVLQKHYRSPLDYTEEGL 309
R+++H G + KMSKS GN V V L Q P IRL +L HYR+ ++ + L
Sbjct: 281 GRHYVHAGMIGWDEHKMSKSRGNLVLVSTLRPQGARPSAIRLGLLAGHYRADRFWSSQLL 340
Query: 310 QHAKNNLER 318
A L R
Sbjct: 341 DDAIARLHR 349
>pir||S72854 cysteine--tRNA ligase (EC 6.1.1.16) - Mycobacterium leprae
>gi|467009|gb|AAA17194.1| (U00017) syC; B2126_C2_193
[Mycobacterium leprae]
Length = 241
Score = 186 bits (468), Expect = 4e-46
Identities = 97/229 (42%), Positives = 128/229 (55%), Gaps = 7/229 (3%)
Query: 26 MYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGFTVLMVMNFTDIDDKIIKRAQETGED 85
MYVCG T YD HLGHA TY+AFD+I R G V V N TD+DD + +RA G D
Sbjct: 1 MYVCGITPYDATHLGHAATYLAFDLIHRLWLDLGHEVHYVQNVTDVDDPLFERADRNGVD 60
Query: 86 PGKLAERFIKVFLEDMNALKVKPADIYPRVTEHIDDIIEFIKKLKEKGYAYEGSD---GV 142
LAER + +F +DM +L++ P Y TE I +I+E + K+ G AY D +
Sbjct: 61 WRDLAEREVALFRDDMASLRILPPHDYVAATETIVEIVELVDKMLVSGAAYVIDDEYPDI 120
Query: 143 YFEVQKFKDYGKLSGVKIEELRKGARVEPGE----GKKNPEDFALWKKAKPGEPKWDSPW 198
YF +G SG + + + G+ GK D LW+ A+PGEP W SP+
Sbjct: 121 YFRADATLQFGYESGYDRDTMLRLYEQSGGDPRRPGKNGELDALLWRAARPGEPSWSSPF 180
Query: 199 GEGRPGWHIECSVMSSKYLGESFDIHGGGNDLIFPHHENEIAQSEACFG 247
G GRPGWH+EC+ ++ +G DI GGG+DLIFPHHE A +E G
Sbjct: 181 GPGRPGWHVECAAIALSRIGIGLDIQGGGSDLIFPHHEFTAAHAECVRG 229
>gb|AAD09434.1| (U09230) cysteinyl-tRNA synthetase [Buchnera aphidicola]
Length = 178
Score = 143 bits (356), Expect = 6e-33
Identities = 75/176 (42%), Positives = 106/176 (59%), Gaps = 1/176 (0%)
Query: 3 IKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGFTV 62
+K++NT T KKE KP+++ ++ +YVCG TVYD+ H+GHART++ FD+I RYL GF V
Sbjct: 2 LKIFNTATSKKEIFKPIKNKKINLYVCGVTVYDFCHIGHARTFVVFDMIVRYLRLIGFQV 61
Query: 63 LMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHIDDI 122
+ N TDIDDKII ++ + D IK +D + L + P D PRVT +I DI
Sbjct: 62 KYIRNITDIDDKIILKSLKEKIDISAFTNIMIKEMNKDFSLLGISPPDEEPRVTNYIIDI 121
Query: 123 IEFIKKLKEKGYAYEGSDG-VYFEVQKFKDYGKLSGVKIEELRKGARVEPGEGKKN 177
I+ I+KL + AY G V F + K YG LS +++L G R+ + KKN
Sbjct: 122 IKVIEKLIKNKNAYVNDHGDVIFSINSDKFYGTLSRQSLDKLISGTRISIDKEKKN 177
>sp|P46241|SYC_BUCAP CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LIGASE) (CYSRS)
Length = 177
Score = 143 bits (356), Expect = 6e-33
Identities = 75/176 (42%), Positives = 106/176 (59%), Gaps = 1/176 (0%)
Query: 3 IKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGFTV 62
+K++NT T KKE KP+++ ++ +YVCG TVYD+ H+GHART++ FD+I RYL GF V
Sbjct: 2 LKIFNTATSKKEIFKPIKNKKINLYVCGVTVYDFCHIGHARTFVVFDMIVRYLRLIGFQV 61
Query: 63 LMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHIDDI 122
+ N TDIDDKII ++ + D IK +D + L + P D PRVT +I DI
Sbjct: 62 KYIRNITDIDDKIILKSLKEKIDISAFTNIMIKEMNKDFSLLGISPPDEEPRVTNYIIDI 121
Query: 123 IEFIKKLKEKGYAYEGSDG-VYFEVQKFKDYGKLSGVKIEELRKGARVEPGEGKKN 177
I+ I+KL + AY G V F + K YG LS +++L G R+ + KKN
Sbjct: 122 IKVIEKLIKNKNAYVNDHGDVIFSINSDKFYGTLSRQSLDKLISGTRISIDKEKKN 177
>sp|P77986|SYC_STAXY CYSTEINYL-TRNA SYNTHETASE (CYSTEINE--TRNA LIGASE) (CYSRS)
>gi|1514657|emb|CAA68888.1| (Y07614) cysteinyl-tRNA
synthetase [Staphylococcus xylosus]
Length = 118
Score = 140 bits (350), Expect = 3e-32
Identities = 63/117 (53%), Positives = 87/117 (73%)
Query: 3 IKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHRGFTV 62
I +YNTLTR+KE +P+ G+V+MYVCGPTVY+Y H+G+AR I +DV+RRY E++G+ V
Sbjct: 2 ITLYNTLTRQKETFEPIEPGKVKMYVCGPTVYNYIHIGNARPAINYDVVRRYFEYQGYEV 61
Query: 63 LMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIYPRVTEHI 119
+ V NFTD+DDK+IKR++E E + +R+IK F ED+ AL VK A PRV H+
Sbjct: 62 IYVSNFTDVDDKLIKRSKELDESVETITDRYIKAFYEDVGALNVKKATSNPRVMNHM 118
>pir||C53739 vacA 5'-region protein - Helicobacter pylori (ATCC 49503)
(fragment) >gi|471728|gb|AAA17656.1| (U05676)
cysteinyl-tRNA synthetase homolog [Helicobacter pylori]
Length = 188
Score = 87.0 bits (212), Expect = 4e-16
Identities = 60/202 (29%), Positives = 105/202 (51%), Gaps = 23/202 (11%)
Query: 277 VRELLQRYSPEVIRLFVLQKHYRSPLDYTEEGLQHAKNNLERLYNTLENIRIAMRNAELS 336
+++ L+ Y E++R ++L HYRS L++ EE L +K L+++Y + + + +
Sbjct: 3 IKDALKNYDGEILRNYLLGVHYRSVLNFNEEDLLVSKKRLDKIYRLKQRVLGNLGGINPN 62
Query: 337 YKWSEKDFEAYEAIREARKKFYDAMDDDFNTAEALKAVFEVSNAINKYILEVDKPKESIL 396
+K K+ + M DD N ++AL + + ++ N+ + + PK L
Sbjct: 63 FK----------------KEILECMQDDLNVSKALSVLESMLSSTNEKLDQ--NPKNKAL 104
Query: 397 R-KALEFFKVVSEVFGI-FED---YFKEEKKGEEEKLIELLVEVRKQLRKEKRFDLADKI 451
+ + L K V E+ GI F+D YF+ E++ IE +E RK+ +++K F AD I
Sbjct: 105 KGEILANLKFVEELLGIGFKDPSAYFQLGVSESEKQEIENKIEERKRAKEQKDFLKADHI 164
Query: 452 REELRKLGIQLEDKGQETVWKR 473
REEL K I L D Q T+W++
Sbjct: 165 REELLKQKIALMDTPQGTIWEK 186
>gb|AAC64627.1| (AF077541) contains similarity to class-I aminoacyl-tRNA
synthetases [Caenorhabditis elegans]
Length = 230
Score = 75.3 bits (182), Expect = 1e-12
Identities = 40/111 (36%), Positives = 60/111 (54%), Gaps = 3/111 (2%)
Query: 3 IKVYNTLTRKKEELKPLRDGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRR-YLEHRGFT 61
+ VYN+LTR+KE P V Y+CGPTV D H+GHAR+Y++ D++RR + ++ G+
Sbjct: 98 LTVYNSLTRQKEVFVPNEGARVGWYICGPTVNDSSHMGHARSYLSLDILRRVFRDYFGYD 157
Query: 62 VLMVMNFTDIDDKIIKRAQETGEDPGKLAERFIKVFLEDMNALKVKPADIY 112
V +MN TD ++ R Q + KL + V+L K Y
Sbjct: 158 VEFIMNITDGVQLLLLRPQNSTH--SKLLQTTFIVYLHKSKRFSSKTISTY 206
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.318 0.139 0.409
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 186641520
Number of Sequences: 2977
Number of extensions: 8528156
Number of successful extensions: 29540
Number of sequences better than 1.0e-10: 72
Number of HSP's better than 0.0 without gapping: 70
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 29206
Number of HSP's gapped (non-prelim): 91
length of query: 477
length of database: 189,106,746
effective HSP length: 56
effective length of query: 421
effective length of database: 155,591,474
effective search space: 65504010554
effective search space used: 65504010554
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 167 (69.5 bits)