BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0961 (PAB0961) DE:dehydrogenase
(392 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||G75056 dehydrogenase PAB0961 - Pyrococcus abyssi (strain Or... 771 0.0
pir||D71175 hypothetical protein PH0600 - Pyrococcus horikoshii ... 733 0.0
pir||C69276 coenzyme F420--quinone oxidoreductase (EC 1.6.5.-) 4... 189 5e-47
gi|11497827 conserved hypothetical protein [Archaeoglobus fulgid... 189 5e-47
gb|AAG19915.1| (AE005075) Vng1663c [Halobacterium sp. NRC-1] 171 9e-42
sp|Q58799|YE04_METJA HYPOTHETICAL PROTEIN MJ1404 >gi|2128840|pir... 131 1e-29
emb|CAC11941.1| (AL445065) conserved hypothetical protein [Therm... 91 2e-17
sp|Q59011|IMDH_METJA INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (IMP... 90 5e-17
gb|AAK42850.1| Conserved hypothetical protein [Sulfolobus solfat... 88 2e-16
sp|O58045|IMDH_PYRHO INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (IMP... 86 8e-16
sp|P42851|IMDH_PYRFU INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (IMP... 84 2e-15
gb|AAK40395.1| Conserved hypothetical protein [Sulfolobus solfat... 83 5e-15
pir||D69030 MJ1225-related protein MTH1223 - Methanobacterium th... 82 1e-14
pir||E75015 IMP dehydrogenase (EC 1.1.1.205) PAB1250 - Pyrococcu... 80 3e-14
pir||F72780 hypothetical protein APE0231 - Aeropyrum pernix (str... 80 6e-14
sp|Q58332|Y922_METJA HYPOTHETICAL PROTEIN MJ0922 >gi|2127741|pir... 79 1e-13
sp|Q58629|YC32_METJA HYPOTHETICAL PROTEIN MJ1232 >gi|2128738|pir... 78 2e-13
pir||D69035 MJ1232 protein homolog MTH126 - Methanobacterium the... 78 2e-13
pir||C69030 MJ1225 protein homolog MTH1222 - Methanobacterium th... 78 2e-13
sp|P15889|YR33_THEPE HYPOTHETICAL 33.4 KD PROTEIN IN RIBOSOMAL R... 76 5e-13
pir||F69185 yhcV homolog MTH644 - Methanobacterium thermoautotro... 76 6e-13
sp|P50100|IMDH_METKA PUTATIVE INOSINE-5'-MONOPHOSPHATE DEHYDROGE... 75 1e-12
gi|11498454 conserved hypothetical protein [Archaeoglobus fulgid... 75 1e-12
sp|Q58622|YC25_METJA HYPOTHETICAL PROTEIN MJ1225 >gi|2128050|pir... 75 2e-12
pir||C72264 IMP dehydrogenase (EC 1.1.1.205) - Thermotoga mariti... 74 3e-12
pir||C75148 hypothetical protein PAB2118 - Pyrococcus abyssi (st... 73 6e-12
gb|AAK43302.1| Conserved hypothetical protein [Sulfolobus solfat... 73 7e-12
pir||H72780 hypothetical protein APE0233 - Aeropyrum pernix (str... 73 7e-12
sp|O67820|IMDH_AQUAE INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (IMP... 72 1e-11
pir||C71188 conserved hypothetical protein MJ1225 homolog - Pyro... 71 2e-11
pir||B72265 hypothetical protein TM1354 - Thermotoga maritima (s... 71 2e-11
>pir||G75056 dehydrogenase PAB0961 - Pyrococcus abyssi (strain Orsay)
>gi|5458861|emb|CAB50348.1| (AJ248287) dehydrogenase
[Pyrococcus abyssi]
Length = 392
Score = 771 bits (1968), Expect = 0.0
Identities = 392/392 (100%), Positives = 392/392 (100%)
Query: 1 MVGIQVQEVMTDRYAKIDINAPLSEAIGIIEKEDPDLILVFDDNVYKGVLTQDLIIRSHL 60
MVGIQVQEVMTDRYAKIDINAPLSEAIGIIEKEDPDLILVFDDNVYKGVLTQDLIIRSHL
Sbjct: 1 MVGIQVQEVMTDRYAKIDINAPLSEAIGIIEKEDPDLILVFDDNVYKGVLTQDLIIRSHL 60
Query: 61 KWDPTKAKVRDVYKPAPVVKPTDDLSHAAKLLLETDLRSLPVGENKAEILGVISDMALLE 120
KWDPTKAKVRDVYKPAPVVKPTDDLSHAAKLLLETDLRSLPVGENKAEILGVISDMALLE
Sbjct: 61 KWDPTKAKVRDVYKPAPVVKPTDDLSHAAKLLLETDLRSLPVGENKAEILGVISDMALLE 120
Query: 121 RVVAEEFGKRKVEEFMTKDVITLGPDDTVAKALATMRDHGISRIPVVDEEGKLEGLVTLH 180
RVVAEEFGKRKVEEFMTKDVITLGPDDTVAKALATMRDHGISRIPVVDEEGKLEGLVTLH
Sbjct: 121 RVVAEEFGKRKVEEFMTKDVITLGPDDTVAKALATMRDHGISRIPVVDEEGKLEGLVTLH 180
Query: 181 DLIIRFIKPRFKAQYGELAGEKIPPFSMKLREAMIKGVITIMPEATIREAVSTMKDNNID 240
DLIIRFIKPRFKAQYGELAGEKIPPFSMKLREAMIKGVITIMPEATIREAVSTMKDNNID
Sbjct: 181 DLIIRFIKPRFKAQYGELAGEKIPPFSMKLREAMIKGVITIMPEATIREAVSTMKDNNID 240
Query: 241 GLVVVDENNKVVGILTVKDLLLPISRMVEKEARFYLQLGGDASALSEFTRERIINDIKRF 300
GLVVVDENNKVVGILTVKDLLLPISRMVEKEARFYLQLGGDASALSEFTRERIINDIKRF
Sbjct: 241 GLVVVDENNKVVGILTVKDLLLPISRMVEKEARFYLQLGGDASALSEFTRERIINDIKRF 300
Query: 301 VDGYADLLGNEGIIYLYIRRFNEKFRGVHLYQARMRVVTDRGVFIARGETWGAIQAVHDA 360
VDGYADLLGNEGIIYLYIRRFNEKFRGVHLYQARMRVVTDRGVFIARGETWGAIQAVHDA
Sbjct: 301 VDGYADLLGNEGIIYLYIRRFNEKFRGVHLYQARMRVVTDRGVFIARGETWGAIQAVHDA 360
Query: 361 IRAIERQLLQKAELERDIRYAKRFIEKLELWR 392
IRAIERQLLQKAELERDIRYAKRFIEKLELWR
Sbjct: 361 IRAIERQLLQKAELERDIRYAKRFIEKLELWR 392
>pir||D71175 hypothetical protein PH0600 - Pyrococcus horikoshii
>gi|3257006|dbj|BAA29689.1| (AP000002) 392aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 392
Score = 733 bits (1873), Expect = 0.0
Identities = 366/392 (93%), Positives = 386/392 (98%)
Query: 1 MVGIQVQEVMTDRYAKIDINAPLSEAIGIIEKEDPDLILVFDDNVYKGVLTQDLIIRSHL 60
MVGIQVQEVMTD+YAKIDI+APLSEAIGIIEKEDPDLILVFDDNVYKGVLTQDLIIRSHL
Sbjct: 1 MVGIQVQEVMTDKYAKIDISAPLSEAIGIIEKEDPDLILVFDDNVYKGVLTQDLIIRSHL 60
Query: 61 KWDPTKAKVRDVYKPAPVVKPTDDLSHAAKLLLETDLRSLPVGENKAEILGVISDMALLE 120
KWDPTKAKVRD+YKPAPVVKPTDDLSHAAKLLLETDLRSLPVGENKAEI+GVISD+ALLE
Sbjct: 61 KWDPTKAKVRDIYKPAPVVKPTDDLSHAAKLLLETDLRSLPVGENKAEIIGVISDIALLE 120
Query: 121 RVVAEEFGKRKVEEFMTKDVITLGPDDTVAKALATMRDHGISRIPVVDEEGKLEGLVTLH 180
RVVAEEFGK+KVEEFMTKDVITL PDDTVAKALA MRDHGISRIP+V+EEGKLEGLVTLH
Sbjct: 121 RVVAEEFGKKKVEEFMTKDVITLTPDDTVAKALAVMRDHGISRIPIVNEEGKLEGLVTLH 180
Query: 181 DLIIRFIKPRFKAQYGELAGEKIPPFSMKLREAMIKGVITIMPEATIREAVSTMKDNNID 240
DLI+RFIKPRFKAQ GEL GEKIPPFSMKLREAMI+GVITI+P AT+REAV+TMKDN+ID
Sbjct: 181 DLILRFIKPRFKAQTGELVGEKIPPFSMKLREAMIRGVITILPTATVREAVATMKDNDID 240
Query: 241 GLVVVDENNKVVGILTVKDLLLPISRMVEKEARFYLQLGGDASALSEFTRERIINDIKRF 300
GLVVVDE NKVVGILTVKDLLLPISRMVEKEA+FYLQLGGDASALS+FTRERIINDIK+F
Sbjct: 241 GLVVVDEGNKVVGILTVKDLLLPISRMVEKEAKFYLQLGGDASALSDFTRERIINDIKKF 300
Query: 301 VDGYADLLGNEGIIYLYIRRFNEKFRGVHLYQARMRVVTDRGVFIARGETWGAIQAVHDA 360
VDGY+DLLGNEGIIYLYIRRFNEKFRGVHLYQARMR+VTD+GVFIARGETWGAIQAVHDA
Sbjct: 301 VDGYSDLLGNEGIIYLYIRRFNEKFRGVHLYQARMRIVTDKGVFIARGETWGAIQAVHDA 360
Query: 361 IRAIERQLLQKAELERDIRYAKRFIEKLELWR 392
IRAIERQLLQKAELERDIRYAKRFIEKLELWR
Sbjct: 361 IRAIERQLLQKAELERDIRYAKRFIEKLELWR 392
>pir||C69276 coenzyme F420--quinone oxidoreductase (EC 1.6.5.-) 41K chain
[validated] - Archaeoglobus fulgidus
Length = 390
Score = 189 bits (475), Expect = 5e-47
Identities = 122/391 (31%), Positives = 216/391 (55%), Gaps = 17/391 (4%)
Query: 6 VQEVMTDRYAKIDINAPLSEAIGIIEKEDPD---LILVFDDNVYKGVLTQDLIIRSHLKW 62
++E++ D + I+ N +S+ ++EK D D ILV +D GV+ + +IR +
Sbjct: 6 LKELIRDDFEVINANETVSKLFPMLEKLDRDKANAILVEEDGKIVGVVREKDLIRGSVLK 65
Query: 63 DPTKAKVRDVYKPAPVVKPTD-DLSHAAKLLLE--TDLRSLPVGENKAEILGVISDMALL 119
+P + KV+ + + + D A+ +E T + + + + ++ + ++ L
Sbjct: 66 NPHETKVKSLLVRTGKIDLNELDPYKVARRFVEDSTPFVIVQIDDKRVGVIYINDFLSAL 125
Query: 120 ERVVAEEFGKRKVEEFMTKDVITLGPDDTVAKALATMRDHGISRIPVVDEEGKLEGLVTL 179
+ +EF KV E M +VIT+ D+ AKAL+ MR HGI R+ VVDE K+ G++T
Sbjct: 126 K----DEFKDVKVREVMNPEVITVRRFDSAAKALSVMRTHGIDRVVVVDENNKVIGILTG 181
Query: 180 HDLIIRFIKPRFKAQYGELAGEKIPPFSMKLREAMIKGVITIMPEATIREAVSTMKDNNI 239
D++ R I PR +A+ G+ +GEK S+ + M V+++ ++ E + M +N I
Sbjct: 182 KDVVDRVISPRKRARMGDSSGEKEKTLSIMVESIMSSPVVSVSRNDSVAEVIDLMVENRI 241
Query: 240 DGLVVVDENNKVVGILTVKDLLLPISRMVEKEAR--FYLQLGGDASALSEFTRERIINDI 297
VVV + GI+ KD+L ++KE+R F +Q+ L EF RE I+ D+
Sbjct: 242 SS-VVVTRDGLPDGIVIKKDIL---EYYLKKESRKEFNVQISTADITLDEFDREAILEDV 297
Query: 298 KRFVDGYADLLGNEGIIYLYIRRFNEKFRGVHLYQARMRVVTDRGVFIARGETWGAIQAV 357
++ + ++D LG E +++YI+R E FR + L R+++ +++G F+ GE+WG AV
Sbjct: 298 EKLMRKFSDFLG-ESFLFIYIKRHKEHFRNLPLIHVRLKLASEKGNFMVSGESWGVEYAV 356
Query: 358 HDAIRAIERQLLQKAELERDIRYAKRFIEKL 388
H A++ +ER++L++ EL D R KRF E++
Sbjct: 357 HVALKKLEREILKEKELLEDKRMIKRFYEEV 387
>gi|11497827 conserved hypothetical protein [Archaeoglobus fulgidus]
>gi|2650431|gb|AAB91022.1| (AE001091) conserved
hypothetical protein [Archaeoglobus fulgidus]
Length = 393
Score = 189 bits (475), Expect = 5e-47
Identities = 122/391 (31%), Positives = 216/391 (55%), Gaps = 17/391 (4%)
Query: 6 VQEVMTDRYAKIDINAPLSEAIGIIEKEDPD---LILVFDDNVYKGVLTQDLIIRSHLKW 62
++E++ D + I+ N +S+ ++EK D D ILV +D GV+ + +IR +
Sbjct: 9 LKELIRDDFEVINANETVSKLFPMLEKLDRDKANAILVEEDGKIVGVVREKDLIRGSVLK 68
Query: 63 DPTKAKVRDVYKPAPVVKPTD-DLSHAAKLLLE--TDLRSLPVGENKAEILGVISDMALL 119
+P + KV+ + + + D A+ +E T + + + + ++ + ++ L
Sbjct: 69 NPHETKVKSLLVRTGKIDLNELDPYKVARRFVEDSTPFVIVQIDDKRVGVIYINDFLSAL 128
Query: 120 ERVVAEEFGKRKVEEFMTKDVITLGPDDTVAKALATMRDHGISRIPVVDEEGKLEGLVTL 179
+ +EF KV E M +VIT+ D+ AKAL+ MR HGI R+ VVDE K+ G++T
Sbjct: 129 K----DEFKDVKVREVMNPEVITVRRFDSAAKALSVMRTHGIDRVVVVDENNKVIGILTG 184
Query: 180 HDLIIRFIKPRFKAQYGELAGEKIPPFSMKLREAMIKGVITIMPEATIREAVSTMKDNNI 239
D++ R I PR +A+ G+ +GEK S+ + M V+++ ++ E + M +N I
Sbjct: 185 KDVVDRVISPRKRARMGDSSGEKEKTLSIMVESIMSSPVVSVSRNDSVAEVIDLMVENRI 244
Query: 240 DGLVVVDENNKVVGILTVKDLLLPISRMVEKEAR--FYLQLGGDASALSEFTRERIINDI 297
VVV + GI+ KD+L ++KE+R F +Q+ L EF RE I+ D+
Sbjct: 245 SS-VVVTRDGLPDGIVIKKDIL---EYYLKKESRKEFNVQISTADITLDEFDREAILEDV 300
Query: 298 KRFVDGYADLLGNEGIIYLYIRRFNEKFRGVHLYQARMRVVTDRGVFIARGETWGAIQAV 357
++ + ++D LG E +++YI+R E FR + L R+++ +++G F+ GE+WG AV
Sbjct: 301 EKLMRKFSDFLG-ESFLFIYIKRHKEHFRNLPLIHVRLKLASEKGNFMVSGESWGVEYAV 359
Query: 358 HDAIRAIERQLLQKAELERDIRYAKRFIEKL 388
H A++ +ER++L++ EL D R KRF E++
Sbjct: 360 HVALKKLEREILKEKELLEDKRMIKRFYEEV 390
>gb|AAG19915.1| (AE005075) Vng1663c [Halobacterium sp. NRC-1]
Length = 380
Score = 171 bits (430), Expect = 9e-42
Identities = 108/387 (27%), Positives = 203/387 (51%), Gaps = 12/387 (3%)
Query: 4 IQVQEVMTDRYAKIDINAPLSEAIGIIEKEDPDLILVFDDNVYKGVLTQDLIIRSHLKWD 63
+ + ++ + Y ++D L + + E+E+P ++V + Y GV+T+ +I+SH+ D
Sbjct: 1 MDISDIAANDYVEVDAEQRLGKVRSLFERENPKGVIVTEAGAYDGVITERQLIQSHIGDD 60
Query: 64 PTKAKVRDVYKPAPVVKPTDDLSHAAKLLLETDLRSLPVGENKAEILGVISDMALLERVV 123
+V + AP V T+D+ A++L+E + PV E + GVI++ A+L+ V+
Sbjct: 61 ---TRVAAMVTDAPKVSRTEDVRETARMLVEGGTKIAPVFE-AGSLWGVITEDAILDAVL 116
Query: 124 AEEFGKRKVEEFMTKDVITLGPDDTVAKALATMRDHGISRIPVVDEEGKLEGLVTLHDLI 183
A V + T+ V+T+ DD++ + + +R+HGISR+PVVD+ G L G+VT +D++
Sbjct: 117 AN-LDALDVRDIYTEHVVTVDEDDSMGRVINLLREHGISRLPVVDDAGLLSGIVTRYDIV 175
Query: 184 IRFIKPRFKAQYGELAGEKIPPFSMKLREAMIKGVITIMPEATIREAVSTMKDNNIDGLV 243
++ K G+ +GE + + + M V T + ++R+AV M ++ G++
Sbjct: 176 DFVVRDTEKTTVGDRSGEIERLLDLPVSDEMTSPVKTASFDDSVRDAVDDMLAHDYSGVI 235
Query: 244 VV--DENNKVVGILTVKDLLLPISRMVEKEARFYLQLGGDASALSEFTRERIINDIKRFV 301
V D+ V GILT D+L +S E+ + + L +R+ + I+ V
Sbjct: 236 VTPDDDERAVGGILTKTDVLRALSYTEEEHLDVQIT---NIDLLDTLSRQEVRERIENVV 292
Query: 302 DGYADLLGNEGIIYLYIRRFNEKFRGVHLYQARMRVVTDRGVFIARGETWGAIQAVHDAI 361
Y D+ + ++ + + EK RG L Q+++R+ T++G GE +GA + H A+
Sbjct: 293 AKYGDMDVHHA--HVRLSKHKEKLRGTPLIQSQIRLRTNKGQIAGTGEGYGADNSFHVAL 350
Query: 362 RAIERQLLQKAELERDIRYAKRFIEKL 388
+ER +L+ +E D Y + + KL
Sbjct: 351 DKLERNVLELKGIEHDEEYEGQLLRKL 377
>sp|Q58799|YE04_METJA HYPOTHETICAL PROTEIN MJ1404 >gi|2128840|pir||C64475 hypothetical
protein MJ1404 - Methanococcus jannaschii
>gi|1592053|gb|AAB99421.1| (U67581) M. jannaschii
predicted coding region MJ1404 [Methanococcus
jannaschii]
Length = 421
Score = 131 bits (326), Expect = 1e-29
Identities = 108/397 (27%), Positives = 193/397 (48%), Gaps = 41/397 (10%)
Query: 1 MVGIQVQEVMTDRYAKIDINAPLSEAIGIIEKEDPDLILVFDDN----VYKGVLTQDLII 56
M+ V+E+MT + + P+S+A+GI+E+ ++V D Y + +DL++
Sbjct: 4 MLNEPVKEIMTKDVVTVTPDTPVSKALGIMEENGFHHLIVVDKKDGKEEYYLISMRDLLL 63
Query: 57 RSHLKWDPTKAKVRDVYKPAPVVKPTDDLSHAAKLLLETDLRSLPVGENKAEILGVISDM 116
S T +VR + A V A +L++ R+ P+ N +++G+I+D
Sbjct: 64 ASS-----TDEEVRSLMYKAHCVHEDTPFLDAVCEMLDSGQRAAPIVNNVGKMVGIITDY 118
Query: 117 ALLERVVAEEFGK-RKVEEFMTKDVITLGPDDTVAKALATMRDHGISRIPVVDEEGKLEG 175
++ R + K KV + MT++VIT+ +D++ KA A MRD+ I R+ VVD+EG G
Sbjct: 119 DIMARAAKSKIMKDTKVTKIMTRNVITINENDSIGKARALMRDNNIGRLVVVDDEGNPVG 178
Query: 176 LVTLHDLIIRFIKPRFKAQYGELAGEKIPPFSMKLREAMIKGVITIMPEATIREAVSTMK 235
+VT D++ + KP+ K GE GEK+P +R M +IT+ +A+ +A M+
Sbjct: 179 MVTEVDILKKVFKPKKKMTAGEFKGEKVPRMGQPVRLIMNTPLITVDVDASAADAARVMQ 238
Query: 236 DNNIDGLVVVDENNKVVGILTVKDLLLPISRMVEKEARFYLQLGGDASALSEFTRERII- 294
+ +I G+ VV + + GI+T D++ I+ + +K A ++L G + ERII
Sbjct: 239 EYDIRGVPVV-KGKSLRGIVTRLDIIKYIADL-KKGAMIEIELHGMLDPEFKDLAERIIA 296
Query: 295 NDIKRFVDGYADLLGNEGIIYLYIRRFNEKFRGVHLYQARMRVVTDRGVFIARG------ 348
++K+ V G I + I++ +K GV Y+ V T +++ G
Sbjct: 297 TEVKKMVKH----AGKIHWIKITIKKERDK-GGVPYYRITTYVKTPNKLYVGEGRPKASL 351
Query: 349 -----------------ETWGAIQAVHDAIRAIERQL 368
E W I + +++ ++ RQL
Sbjct: 352 PNKLEAEGEDIAYVSEHERWEFIDVLKESLESVLRQL 388
>emb|CAC11941.1| (AL445065) conserved hypothetical protein [Thermoplasma
acidophilum]
Length = 362
Score = 90.9 bits (222), Expect = 2e-17
Identities = 82/373 (21%), Positives = 179/373 (47%), Gaps = 16/373 (4%)
Query: 4 IQVQEVMTDRYAKIDINAPLSEAIGIIEKEDPDLILVFDDNVYKGVLT-QDLIIRSHLKW 62
++V E+MT + I+ S+ + + + + V D + Y G++T DL+ + ++
Sbjct: 1 MKVSELMTTDPITVSIDDTFSKVMSKMNETGIHQLPVMDGDRYAGMITYSDLLKKRSIQ- 59
Query: 63 DPTKAKVRDVYKPAPVVKPTDDLSHAAKLLLETDLRSLPVGENKAEILGVISDMALLERV 122
K+K+ + P + DD+ A +L+ +T L +LPV + K +++G+IS +++ +
Sbjct: 60 --VKSKISNYTISTPTLNADDDVLEAVRLIKDTGLSALPVFQ-KGKLVGIISRTDIIKNL 116
Query: 123 VA-EEFGKRKVEEFMTKDVITLGPDDTVAKALATMRDHGISRIPVVDEEGKLEGLVTLHD 181
+ ++ + M+ D I + DD + +A +MR IPV + KL G++ L+
Sbjct: 117 PQIVDVRDVRIFQIMSSDPIYVYEDDDIEEAFDSMRMLNEVEIPVASRDEKLSGIIRLNS 176
Query: 182 LIIRFIKPRFKAQYGELAGEKIPPFSMKLREAMIKGVITIMPEATIREAVSTMKDNNIDG 241
++ + + K +YG GEK P +K + +++ +++ A I EAV M ++
Sbjct: 177 ILNILYRQKEKIKYGGY-GEK-EPVEIKCK-SLMDPPVSVDRYAGIDEAVKLMMQYSLH- 232
Query: 242 LVVVDENNKVVGILTVKDLLLPISRMVEKEARFYLQLGGDASALSEFTRERIINDIKRFV 301
++ V ++ K+VGI+ DL+ I E + +++ G E + +RF+
Sbjct: 233 IMPVTDSGKIVGIVDFSDLINMIK--TESKEGILIEISG-LDVYDEDLYDIAFELSERFL 289
Query: 302 DGYADLLG-NEGIIYLYIRRFNEKFRGVHLYQARMRVVTDRGVFIARGETWGAIQAVHDA 360
D ++ + ++G + +++ ++ K +G Y R R+ + G W + + +
Sbjct: 290 DKFSKMTDVSQGKLLIHVMKY--KTQGSTKYSIRTRISAPPLFLVQNGSGWNFAEVLGEI 347
Query: 361 IRAIERQLLQKAE 373
E ++ + E
Sbjct: 348 FDRYEERIKKMKE 360
>sp|Q59011|IMDH_METJA INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (IMP DEHYDROGENASE) (IMPDH)
(IMPD) >gi|2117504|pir||G64501 IMP dehydrogenase (EC
1.1.1.205) - Methanococcus jannaschii
>gi|1592337|gb|AAB99638.1| (U67602)
inosine-5'-monophosphate dehydrogenase, (guaB)
[Methanococcus jannaschii]
Length = 496
Score = 89.7 bits (219), Expect = 5e-17
Identities = 51/152 (33%), Positives = 84/152 (54%), Gaps = 18/152 (11%)
Query: 110 LGVISDMALLERVVAEEFGKRKVEEFMTKDVITLGPDDTVAKALATMRDHGISRIPVVDE 169
LGVI +E V + +K +E + KDVIT+ PDDTV +A+ M + IS +PVVD
Sbjct: 70 LGVIHRNMSIEEQVHQVQAVKKADEVVIKDVITVSPDDTVGEAINVMETYSISGLPVVDN 129
Query: 170 EGKLEGLVTLHDLIIRFIKPRFKAQYGELAGEKIPPFSMKLREAMIKGVITIMPEATIRE 229
E KL G++T D ++ I+ + K K+++ M K V+ + E
Sbjct: 130 EDKLVGIITHRD--VKAIEDKTK----------------KVKDVMTKDVVCAKEDVEEEE 171
Query: 230 AVSTMKDNNIDGLVVVDENNKVVGILTVKDLL 261
A+ M N ++ L +VD+ N+++GI+T++D+L
Sbjct: 172 ALELMYANRVERLPIVDDENRLIGIITLRDIL 203
>gb|AAK42850.1| Conserved hypothetical protein [Sulfolobus solfataricus]
Length = 250
Score = 88.2 bits (215), Expect = 2e-16
Identities = 62/242 (25%), Positives = 125/242 (51%), Gaps = 21/242 (8%)
Query: 23 LSEAIGIIEKEDPDLILVFDDNVYKGVLTQDLIIRSHLKWDPT--KAKVRDVY-KPAPVV 79
L EAI I+ I+V + G+++ ++ S ++ KV+D+ K +V
Sbjct: 20 LKEAIDILSNNPSGRIVVLKEEKPIGIVSTRDVVASFSEYGTNIYDLKVKDIMSKDLVIV 79
Query: 80 KPTDDLSHAAKLLLETDLRSLPVGENKAEILGVISDMALLERVVAEEFGKRKVEEFMTKD 139
P DD++H +++L ++ +PV +N I+G+ ++ +L+ + + F V+ M+ +
Sbjct: 80 SPNDDVNHVVRIMLMNNIGGIPVVDNNV-IVGIFTEREILKLIASSMFSGL-VDSVMSSN 137
Query: 140 VITLGPDDTVAKALATMRDHGISRIPVVDEEGKLEGLVTLHDLIIRFIKPRFKAQYGELA 199
+I++G ++T+ A M + + R+PV ++ +L G++T D++ ++ A+ +
Sbjct: 138 IISIGEENTIMDAAKLMVMNNVRRLPVFSKDNRLVGIITAADIV------KYLAKNKNIG 191
Query: 200 GEKIPPFSMKLREAMIKGVITIMPEATIREAVSTMKDNNIDGLVVVDENNKVVGILTVKD 259
K+ +A K ITI +I A M + I G ++V EN K+VGI+T +D
Sbjct: 192 ---------KVLDAGTKNPITINRYYSILNAAKLMIEKRI-GTLLVMENQKLVGIVTERD 241
Query: 260 LL 261
L+
Sbjct: 242 LM 243
>sp|O58045|IMDH_PYRHO INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (IMP DEHYDROGENASE) (IMPDH)
(IMPD) >gi|7427688|pir||E71456 IMP dehydrogenase (EC
1.1.1.205) - Pyrococcus horikoshii
>gi|3256697|dbj|BAA29380.1| (AP000001) 486aa long
hypothetical inosine-5'-monophosphate dehydrogenase
[Pyrococcus horikoshii]
Length = 486
Score = 85.8 bits (209), Expect = 8e-16
Identities = 68/196 (34%), Positives = 101/196 (50%), Gaps = 29/196 (14%)
Query: 110 LGVISDMALLERVVAEEFGKRKVEEFMTKDVITLGPDDTVAKALATMRDHGISRIPVVDE 169
LGVI +E V + ++ E + +DVIT+ PD+TV AL M HGI +PVV++
Sbjct: 73 LGVIHRNMGIEEQVEQVKRVKRAERLIVEDVITIAPDETVDFALFLMEKHGIDGLPVVED 132
Query: 170 EGKLEGLVTLHDLIIRFIKPRFKAQYGELAGEKIPPFSMKLREAMIKGVITIMPEATIRE 229
E K+ G++T D+ A+ G+L ++E M K VIT+ + E
Sbjct: 133 E-KVVGIITKKDIA---------AREGKL-----------VKELMTKEVITVPESIEVEE 171
Query: 230 AVSTMKDNNIDGLVVVDENNKVVGILTVKDLLLPISRMVEKEARFYLQLGGD---ASALS 286
A+ M +N ID L VVDE K+VG++T+ DL ++R K A G+ A+A+S
Sbjct: 172 ALKIMIENRIDRLPVVDERGKLVGLITMSDL---VARKKYKNA--VRDENGELLVAAAVS 226
Query: 287 EFTRERIINDIKRFVD 302
F +R I K VD
Sbjct: 227 PFDIKRAIELDKAGVD 242
Score = 72.6 bits (175), Expect = 7e-12
Identities = 73/264 (27%), Positives = 132/264 (49%), Gaps = 21/264 (7%)
Query: 8 EVMTDRYAKIDINAP-LSEAIGIIEKEDPDLILVFDDNVYKGVLTQDLIIRSHLKW-DPT 65
+V T + +N P LS A+ + + + + + + + GV+ +++ I ++
Sbjct: 35 DVSTRITPNVKLNIPILSAAMDTVTEWEMAVAMAREGGL--GVIHRNMGIEEQVEQVKRV 92
Query: 66 KAKVRDVYKPAPVVKPTDDLSHAAKLLLETDLRSLPVGENKAEILGVISDMALLERVVAE 125
K R + + + P + + A L+ + + LPV E++ +++G+I+ ++ +A
Sbjct: 93 KRAERLIVEDVITIAPDETVDFALFLMEKHGIDGLPVVEDE-KVVGIIT-----KKDIAA 146
Query: 126 EFGKRKVEEFMTKDVITLGPDDTVAKALATMRDHGISRIPVVDEEGKLEGLVTLHDLIIR 185
GK V+E MTK+VIT+ V +AL M ++ I R+PVVDE GKL GL+T+ DL+ R
Sbjct: 147 REGKL-VKELMTKEVITVPESIEVEEALKIMIENRIDRLPVVDERGKLVGLITMSDLVAR 205
Query: 186 -FIKPRFKAQYGE-LAGEKIPPFSMK----LREAMIKGVITIMPEATIREAVSTMKD--N 237
K + + GE L + PF +K L +A + ++ A +A+ +MK+
Sbjct: 206 KKYKNAVRDENGELLVAAAVSPFDIKRAIELDKAGVDVIVVDTAHAHNLKAIKSMKEMRQ 265
Query: 238 NIDGLVVVDE--NNKVVGILTVKD 259
+D +V N K V LT D
Sbjct: 266 KVDADFIVGNIANPKAVDDLTFAD 289
>sp|P42851|IMDH_PYRFU INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (IMP DEHYDROGENASE) (IMPDH)
(IMPD) >gi|2117506|pir||JC4998 IMP dehydrogenase (EC
1.1.1.205) - Pyrococcus furiosus
>gi|595287|gb|AAC44532.1| (U08814) IMP dehydrogenase
[Pyrococcus furiosus]
Length = 485
Score = 84.3 bits (205), Expect = 2e-15
Identities = 50/152 (32%), Positives = 81/152 (52%), Gaps = 21/152 (13%)
Query: 110 LGVISDMALLERVVAEEFGKRKVEEFMTKDVITLGPDDTVAKALATMRDHGISRIPVVDE 169
LGVI +E V + ++ E F+ +DVIT+ PD+T+ AL M HGI +PVV+E
Sbjct: 73 LGVIHRNMSIEEQVEQVKRVKRAERFIVEDVITIAPDETIDYALFLMEKHGIDGLPVVEE 132
Query: 170 EGKLEGLVTLHDLIIRFIKPRFKAQYGELAGEKIPPFSMKLREAMIKGVITIMPEATIRE 229
+ ++ G++T D+ R ++E M + VIT+ + E
Sbjct: 133 D-RVVGIITKKDIAARE--------------------GRTVKELMTREVITVPESVDVEE 171
Query: 230 AVSTMKDNNIDGLVVVDENNKVVGILTVKDLL 261
A+ M +N ID L VV+E+ K+VG++T+ DL+
Sbjct: 172 ALKIMMENRIDRLPVVNEDGKLVGLITMSDLV 203
Score = 71.0 bits (171), Expect = 2e-11
Identities = 70/264 (26%), Positives = 129/264 (48%), Gaps = 21/264 (7%)
Query: 8 EVMTDRYAKIDINAP-LSEAIGIIEKEDPDLILVFDDNVYKGVLTQDLIIRSHLKW-DPT 65
+V T + +N P LS A+ + + + + + + + GV+ +++ I ++
Sbjct: 35 DVSTQITPNVKLNIPILSAAMDTVTEWEMAVAMAREGGL--GVIHRNMSIEEQVEQVKRV 92
Query: 66 KAKVRDVYKPAPVVKPTDDLSHAAKLLLETDLRSLPVGENKAEILGVISDMALLERVVAE 125
K R + + + P + + +A L+ + + LPV E ++G+I+ ++ +A
Sbjct: 93 KRAERFIVEDVITIAPDETIDYALFLMEKHGIDGLPVVEED-RVVGIIT-----KKDIAA 146
Query: 126 EFGKRKVEEFMTKDVITLGPDDTVAKALATMRDHGISRIPVVDEEGKLEGLVTLHDLIIR 185
G R V+E MT++VIT+ V +AL M ++ I R+PVV+E+GKL GL+T+ DL+ R
Sbjct: 147 REG-RTVKELMTREVITVPESVDVEEALKIMMENRIDRLPVVNEDGKLVGLITMSDLVAR 205
Query: 186 -FIKPRFKAQYGE-LAGEKIPPFSMK----LREAMIKGVITIMPEATIREAVSTMKDN-- 237
K + + GE L + PF ++ L A + ++ A +A+ MK+
Sbjct: 206 KKYKNAVRNEKGELLVAAAVSPFDLRRAIELDRAGVDVIVVDTAHAHNLKAIKAMKEMRQ 265
Query: 238 --NIDGLVVVDENNKVVGILTVKD 259
+ D +V N K V LT D
Sbjct: 266 KVSADFIVGNIANPKAVDDLTFAD 289
>gb|AAK40395.1| Conserved hypothetical protein [Sulfolobus solfataricus]
Length = 380
Score = 83.1 bits (202), Expect = 5e-15
Identities = 79/356 (22%), Positives = 168/356 (47%), Gaps = 19/356 (5%)
Query: 23 LSEAIGIIEKEDPDLILVFDDNVYKGVLT-QDLIIRSHLKWDPTKAKVRDVYKPAPVVKP 81
LS+ I +++ + V D G+++ +DL+ R + K ++ P+ V+
Sbjct: 20 LSDIISKMKENKMWTVPVIKDRKLIGLISYKDLLSRRV----SLETKAINIMSPSVTVQI 75
Query: 82 TDDLSHAAKLLLETDLRSLPVGENKAEILGVISDMALLERVV-AEEFGK-RKVEEFMTKD 139
+D++ T R +PV K E +G+++ +LL ++ A E + R E+MT
Sbjct: 76 DEDINRLIAKFYTTKARVIPVINEKREFIGLVTRESLLSYLLKANEIPENRTAREYMTSP 135
Query: 140 VITLGPDDTVAKALATMRDHGISRIPVVDEEGKLEGLVTLHDLIIRFIKPRFKAQYGELA 199
++ +D++A+A M ISR+P +E +L G+++ D++ + + +
Sbjct: 136 ATSIDENDSIARARWLMIRDNISRLPAT-KEYRLTGIISARDIVDALYSVSGRKRESIMK 194
Query: 200 GEKIPPFSMKLREAMIKGVITIMPEATIREAVSTMKDNNIDGLVVVDENNKVVGILTVKD 259
E+ +M ++E M VIT + ++ + V + I G+ V+ E +++ G+++ D
Sbjct: 195 DEE-RVMAMPVKEIMKYPVITANGKDSLTDVVEKLLKFRISGMPVM-EGDRLSGVISGLD 252
Query: 260 LLLPISRMVEKEARFYLQLGGDASALSEFTRERIINDIKRFVDGYADLLGNEGIIYLYIR 319
++ ++ ++ ++ + + EF I+DI ++ Y + + +
Sbjct: 253 IIKAVAEKMQLSIPIEAKIPQELKSNLEFKAN--IDDI---LERYLSKIERLTEVINFKV 307
Query: 320 RFNEKFR----GVHLYQARMRVVTDRGVFIARGETWGAIQAVHDAIRAIERQLLQK 371
F E+ R LY A +RV T G ++AR W + A+ +A+ IE ++L+K
Sbjct: 308 SFKEEMRSSTGNKKLYTAMVRVTTKIGDYVARDTDWEPVVALKNAVEKIEERILRK 363
>pir||D69030 MJ1225-related protein MTH1223 - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2622334|gb|AAB85712.1| (AE000890)
inosine-5'-monophosphate dehydrogenase related protein
II [Methanobacterium thermoautotrophicum]
Length = 281
Score = 81.9 bits (199), Expect = 1e-14
Identities = 76/280 (27%), Positives = 132/280 (47%), Gaps = 22/280 (7%)
Query: 1 MVGIQVQEVMTDRYAKIDINAPLSEAIGIIEKEDPDLILVFD-DNVYKGVLTQDLIIRSH 59
MV + + +MTD +D ++ A ++ + ++V D D G++T+ I R
Sbjct: 1 MVTVDIGSIMTDEVIVMDETQQVAYARNLMLRHGISRVVVVDADGKPVGIVTETDITRKL 60
Query: 60 LKWDPT-------KAKVRDVYKPAPV-VKPTDDLSHAAKLLLETDLRSLPVGENKAEILG 111
P K +R V PV V D AA+L+L ++ SL V + + E+ G
Sbjct: 61 RVNGPDWRRRPIDKISIRRVMTENPVTVNVNDTPRDAAELMLRKNVGSLLVMDGE-ELAG 119
Query: 112 VISDMALLERVVAEEFGKRKVEEFMTKDVITLGPDDTVAKALATMRDHGISRIPVVDEEG 171
+++ LL G+ KV + MT+DV T+ P+ T++ + M ++ ISR+ VV + G
Sbjct: 120 IVTKKDLLRFFKDRCAGRWKVRDLMTEDVKTVTPNHTLSHVIGVMEENNISRV-VVTDNG 178
Query: 172 KLEGLVTLHDL-IIRFIKPR---------FKAQYGELAGEKIPPFSMKLREAMIKGVITI 221
+EG++T +L F P F ++ E + + M + VI +
Sbjct: 179 AVEGIITSENLSFATFEDPERGIPVERVYFISRTSEEKKRVRTIAMLTAGDIMTEDVIKV 238
Query: 222 MPEATIREAVSTMKDNNIDGLVVVDENNKVVGILTVKDLL 261
P A + M +N I GL VV E++++VGI+T D++
Sbjct: 239 EPSVDASSAAAMMLENGISGLPVV-EDDELVGIITKTDII 277
>pir||E75015 IMP dehydrogenase (EC 1.1.1.205) PAB1250 - Pyrococcus abyssi
(strain Orsay) >gi|5459077|emb|CAB50563.1| (AJ248288)
INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (EC 1.1.1.205)
(IMP DEHYDROGENASE) (IMPDH) (IMPD). [Pyrococcus abyssi]
Length = 485
Score = 80.4 bits (195), Expect = 3e-14
Identities = 51/152 (33%), Positives = 82/152 (53%), Gaps = 21/152 (13%)
Query: 110 LGVISDMALLERVVAEEFGKRKVEEFMTKDVITLGPDDTVAKALATMRDHGISRIPVVDE 169
LGVI +E V + +K E F+ +DVIT+ P++TV AL M H I +PVV+
Sbjct: 73 LGVIHRNMSIEEQVEQVKRVKKAERFIVEDVITISPEETVDFALFLMEKHDIDGLPVVEN 132
Query: 170 EGKLEGLVTLHDLIIRFIKPRFKAQYGELAGEKIPPFSMKLREAMIKGVITIMPEATIRE 229
E K+ G+++ D+ A+ G+L ++E M K VIT+ + E
Sbjct: 133 E-KVVGIISKKDIA---------AREGKL-----------VKELMTKDVITVPENIEVEE 171
Query: 230 AVSTMKDNNIDGLVVVDENNKVVGILTVKDLL 261
A+ M +N ID L VVD+ +++G++T+ DL+
Sbjct: 172 ALKIMIENRIDRLPVVDKEGRLIGLITMSDLV 203
Score = 78.0 bits (189), Expect = 2e-13
Identities = 75/264 (28%), Positives = 133/264 (49%), Gaps = 21/264 (7%)
Query: 8 EVMTDRYAKIDINAP-LSEAIGIIEKEDPDLILVFDDNVYKGVLTQDLIIRSHLKW-DPT 65
+V T + +N P LS A+ + + + + + + + GV+ +++ I ++
Sbjct: 35 DVSTQITPNVKLNIPILSAAMDTVTEWEMAVAMAREGGL--GVIHRNMSIEEQVEQVKRV 92
Query: 66 KAKVRDVYKPAPVVKPTDDLSHAAKLLLETDLRSLPVGENKAEILGVISDMALLERVVAE 125
K R + + + P + + A L+ + D+ LPV EN+ +++G+IS ++ +A
Sbjct: 93 KKAERFIVEDVITISPEETVDFALFLMEKHDIDGLPVVENE-KVVGIIS-----KKDIAA 146
Query: 126 EFGKRKVEEFMTKDVITLGPDDTVAKALATMRDHGISRIPVVDEEGKLEGLVTLHDLIIR 185
GK V+E MTKDVIT+ + V +AL M ++ I R+PVVD+EG+L GL+T+ DL+ R
Sbjct: 147 REGKL-VKELMTKDVITVPENIEVEEALKIMIENRIDRLPVVDKEGRLIGLITMSDLVAR 205
Query: 186 -FIKPRFKAQYGE-LAGEKIPPF----SMKLREAMIKGVITIMPEATIREAVSTMKD--N 237
K + + GE L + PF +++L A ++ A +A+ MK+
Sbjct: 206 KKYKNAVRDENGELLVAAAVSPFDIRRAIELDRAGADVIVVDTAHAHNLKAIKAMKEMRQ 265
Query: 238 NIDGLVVVDE--NNKVVGILTVKD 259
+D +V N K V LT D
Sbjct: 266 KVDADFIVGNIANPKAVDDLTFAD 289
>pir||F72780 hypothetical protein APE0231 - Aeropyrum pernix (strain K1)
>gi|5103623|dbj|BAA79144.1| (AP000058) 287aa long
hypothetical protein [Aeropyrum pernix]
Length = 287
Score = 79.6 bits (193), Expect = 6e-14
Identities = 53/161 (32%), Positives = 85/161 (51%), Gaps = 22/161 (13%)
Query: 131 KVEEFMTKDVITLGPDDTVAKALATMRDHGISRIPVVDEEGKLEGLVTLHDLIIRFIKPR 190
+V +MT+DV T+ PDDT+A A M H ISR+PVV E KL G++T+ D+ ++ +
Sbjct: 4 RVVSYMTRDVYTVSPDDTLAHARKLMLTHDISRLPVV-EGSKLRGIITITDIADALVR-K 61
Query: 191 FKAQYGELAGEKIPPFSMKLREAMIKGVITIMPEATIREAVSTMKDNNIDGLVVVDENNK 250
+ ++ P S+ +RE M + V+TI +++ A S M +NI G+ VV +
Sbjct: 62 YPSR---------PANSIYVREVMARDVVTIEGTKSVKTAASLMLKHNIGGVPVVAPDGT 112
Query: 251 VVGILTVKDLLLPISRMVEKEARFYLQLGGDASALSEFTRE 291
+ GI+T DL R+Y + + + EF RE
Sbjct: 113 LEGIITRTDL-----------TRYYSEKMKGVNLVKEFMRE 142
Score = 71.0 bits (171), Expect = 2e-11
Identities = 61/195 (31%), Positives = 95/195 (48%), Gaps = 24/195 (12%)
Query: 70 RDVYKPAPVVKPTDDLSHAAKLLLETDLRSLPVGE-NKAEILGVISDMA--LLERVVAEE 126
RDVY V P D L+HA KL+L D+ LPV E +K + I+D+A L+ + +
Sbjct: 11 RDVY----TVSPDDTLAHARKLMLTHDISRLPVVEGSKLRGIITITDIADALVRKYPSRP 66
Query: 127 FGKRKVEEFMTKDVITLGPDDTVAKALATMRDHGISRIPVVDEEGKLEGLVTLHDLIIRF 186
V E M +DV+T+ +V A + M H I +PVV +G LEG++T DL R+
Sbjct: 67 ANSIYVREVMARDVVTIEGTKSVKTAASLMLKHNIGGVPVVAPDGTLEGIITRTDL-TRY 125
Query: 187 IKPRFKAQYGELAGEKIPPFSMKL-REAMIKGVITIMPEATIREAVSTMKDNNIDGLVVV 245
+ K L E + K RE I V+ +M + + G V++
Sbjct: 126 YSEKMKGV--NLVKEFMREIYAKARREHSIFYVLKLM-------------EIDATGKVLI 170
Query: 246 DENNKVVGILTVKDL 260
+ K+VG++T +D+
Sbjct: 171 LDGGKLVGVITKRDI 185
>sp|Q58332|Y922_METJA HYPOTHETICAL PROTEIN MJ0922 >gi|2127741|pir||B64415 yhcV homolog -
Methanococcus jannaschii >gi|1591595|gb|AAB98926.1|
(U67535) conserved hypothetical protein [Methanococcus
jannaschii]
Length = 138
Score = 78.8 bits (191), Expect = 1e-13
Identities = 49/143 (34%), Positives = 81/143 (56%), Gaps = 18/143 (12%)
Query: 131 KVEEFMTKDVITLGPDDTVAKALATMRDHGISRIPVVDEEGKLEGLVTLHDLIIRFIKPR 190
KV++ MTK+VIT + V +A M + IS +PV+D+E K+ G+VT D+ I+ +
Sbjct: 9 KVKDVMTKNVITAKRHEGVVEAFEKMLKYKISSLPVIDDENKVIGIVTTTDIGYNLIRDK 68
Query: 191 FKAQYGELAGEKIPPFSMKLREAMIKGVITIMPEATIREAVSTM-----KDNNIDGLVVV 245
+ + + + M K VITI +A+I EA+ M K+ I+ L VV
Sbjct: 69 YTLE-------------TTIGDVMTKDVITIHEDASILEAIKKMDISGKKEEIINQLPVV 115
Query: 246 DENNKVVGILTVKDLLLPISRMV 268
D+NNK+VGI++ D++ IS+++
Sbjct: 116 DKNNKLVGIISDGDIIRTISKII 138
>sp|Q58629|YC32_METJA HYPOTHETICAL PROTEIN MJ1232 >gi|2128738|pir||G64453 conserved
hypothetical protein MJ1232 - Methanococcus jannaschii
>gi|1591864|gb|AAB99237.1| (U67564) conserved
hypothetical protein [Methanococcus jannaschii]
Length = 296
Score = 77.6 bits (188), Expect = 2e-13
Identities = 61/202 (30%), Positives = 96/202 (47%), Gaps = 37/202 (18%)
Query: 83 DDLSH----AAKLLLETDLRSLPVGE---------NKAEILGVISDMALLERVV------ 123
D +SH ++K+ +E D + +G+ NK I G I + R++
Sbjct: 104 DTVSHEKCCSSKIHIEGDTKHFNIGDIIRVGPTYHNKIIINGKIIGRDDIHRILLIDVLG 163
Query: 124 AEEFGKRKVEEFMTKDVITLGPDDTVAKALATMRDHGISRIPVVDEEGKLEGLVTLHDLI 183
KV + K+V T+ P+ T+ + + IS PVVD + KL G+++LHD+
Sbjct: 164 VSSIPNIKVGDVGIKEVWTINPNCTLRETAKLFAEKYISGAPVVDND-KLVGVISLHDI- 221
Query: 184 IRFIKPRFKAQYGELAGEKIPPFSMKLREAMIKGVITIMPEATIREAVSTMKDNNIDGLV 243
E I K++E M + VITI + I +A+ M NN+ LV
Sbjct: 222 ----------------AENIDNIDKKVKEVMRRDVITIHKDEKIYDALKIMNKNNVGRLV 265
Query: 244 VVDENNKVVGILTVKDLLLPIS 265
+VD+NNK+VGI+T D+L IS
Sbjct: 266 IVDDNNKIVGIITRTDILKIIS 287
>pir||D69035 MJ1232 protein homolog MTH126 - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2621166|gb|AAB84632.1| (AE000802)
inosine-5'-monophosphate dehydrogenase related protein
VII [Methanobacterium thermoautotrophicum]
Length = 302
Score = 77.6 bits (188), Expect = 2e-13
Identities = 53/178 (29%), Positives = 88/178 (48%), Gaps = 22/178 (12%)
Query: 90 KLLLETDLRSLPVGENKAEILGVI------SDMALLERVVAEEFGKRKVEEFMTKDVITL 143
KL L +R P NK + GV+ ++ LL+ K+ V E T+D++TL
Sbjct: 134 KLDLGDRVRIGPTPVNKLVVDGVVVGRDDMDNIILLDTTAIRSIPKKTVAEVATRDLVTL 193
Query: 144 GPDDTVAKALATMRDHGISRIPVVDEEGKLEGLVTLHDLIIRFIKPRFKAQYGELAGEKI 203
PD TV +A A + GI P+V+++ +++G+VTL D+ AG +
Sbjct: 194 APDITVKEAAARLSSLGIEGAPIVEDD-EVKGIVTLSDITASIA-----------AGTEF 241
Query: 204 PPFSMKLREAMIKGVITIMPEATIREAVSTMKDNNIDGLVVVDENNKVVGILTVKDLL 261
M++ + M K +IT+ + I +A+ M +NI L+V D + GI+T D+L
Sbjct: 242 ----MQVSDIMSKNIITVKQDTMIADAIEVMNKHNIGRLIVTDSEGRPTGIITRTDIL 295
>pir||C69030 MJ1225 protein homolog MTH1222 - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2622333|gb|AAB85711.1| (AE000890)
inosine-5'-monophosphate dehydrogenase related protein I
[Methanobacterium thermoautotrophicum]
Length = 275
Score = 77.6 bits (188), Expect = 2e-13
Identities = 69/275 (25%), Positives = 135/275 (49%), Gaps = 24/275 (8%)
Query: 1 MVGIQVQEVMTDRYAKIDINAPLSEAIGIIEKEDPDLILVFDDNV-----YKGVLTQ-DL 54
M + ++ +M++ ID + + +A+ +++K + +LV + N G++T+ D+
Sbjct: 1 MESMIIKNIMSEDPVCIDKDQNICDALRLMDKRNVSRLLVINTNSDHERELVGIVTEKDI 60
Query: 55 IIR----SHLKWDPTKAKVRDVYKPAPVV-KPTDDLSHAAKLLLETDLRSLPVGENKAEI 109
++ + P+ V V P + +P D +AA ++LE ++ SLPV + EI
Sbjct: 61 ALKLGSSRYGNMAPSHFHVSTVMTPELITAEPDMDAGNAASVMLENNIGSLPVLHD-GEI 119
Query: 110 LGVISDMALLERVVAEEFGKRKVEEFMTKDVITLGPDDTVAKALATMRDHGISRIPVVDE 169
+G+++ LL+ + K + M+ ++IT+ P + V A M D GI R+ V+ E
Sbjct: 120 MGIVTKSDLLDICRGRAYEKYTAADVMSTEMITVSPAERVVHARRIMIDAGIGRLLVM-E 178
Query: 170 EGKLEGLVTLHDLIIRFIKPRFKAQYGELAGEKIPPFSMK---LREAMIKGVITIMPEAT 226
E +L G++T D+ R + +L ++ P ++ + + M + V TI E
Sbjct: 179 EDELAGILTARDM------TRAVINFRKLVPDRHKPSRIRNLLVEDIMKQNVRTIEEETP 232
Query: 227 IREAVSTMKDNNIDGLVVVDENNKVVGILTVKDLL 261
+ E S M + G V+ + +V GI+T D+L
Sbjct: 233 VTEVASLMLETGYGGFPVIKQ--EVEGIVTKTDIL 265
>sp|P15889|YR33_THEPE HYPOTHETICAL 33.4 KD PROTEIN IN RIBOSOMAL RNA OPERON
>gi|81092|pir||S08244 conserved hypothetical protein
MJ1225 homolog - Thermofilum pendens
>gi|48226|emb|CAA32944.1| (X14835) open reading frame 1
(300 AA) [Thermofilum pendens]
Length = 300
Score = 76.5 bits (185), Expect = 5e-13
Identities = 61/227 (26%), Positives = 112/227 (48%), Gaps = 20/227 (8%)
Query: 41 FDDNVYKGVLTQDLIIRSHLKWDPTKAKVRDVYKPAPVVKPTDDLSHAAKLLLETDLRSL 100
F+ +VYK + + LK+DP P V DL +L++E + +L
Sbjct: 73 FNGDVYKALEQTGV---EFLKYDP------------PYVYTRSDLREVIELMVERGIGAL 117
Query: 101 PVGENKAEILGVISDMALLERVVAEEFGKRKVEEFMTKDVITLGPDDTVAKALATMRDHG 160
V + ++G++S+ ++ ++A KV+E MT +V+ L P D++ + + M +
Sbjct: 118 AVVDEDLRVVGIVSERHVIS-LLANVETHVKVKEIMTSEVVYLSPMDSLFEGMRVMSERR 176
Query: 161 ISRIPVVDEEGKLEGLVTLHDLIIRFIKPRFKAQYGELAGEKIPPFSMKLREAMIKGVIT 220
I R+P+V E +L G+VT+ D++ + A+ E G + + L K V+
Sbjct: 177 IRRLPLVSGE-ELRGIVTIKDVLSYVSREDVLARLKE--GSRSAVYDTPLVYISSKPVLA 233
Query: 221 IMPEATIREAVSTMKDNNIDGLVVVDENNKVVGILTVKDLLLPISRM 267
+ + + AVS MK + I G +VV + K GI+T +D+L + R+
Sbjct: 234 VEDDVDVGLAVSLMKKHGI-GALVVTHDGKPRGIVTERDVLTRLPRV 279
>pir||F69185 yhcV homolog MTH644 - Methanobacterium thermoautotrophicum (strain
Delta H) >gi|2621725|gb|AAB85149.1| (AE000844) conserved
protein [Methanobacterium thermoautotrophicum]
Length = 157
Score = 76.1 bits (184), Expect = 6e-13
Identities = 46/150 (30%), Positives = 80/150 (52%), Gaps = 19/150 (12%)
Query: 131 KVEEFMTKDVITLGPDDTVAKALATMRDHGISRIPVVDEEGKLEGLVTLHDLI------- 183
+V++ M DVIT+ ++ A +R++ IS PVVDE+GKL G+++ D++
Sbjct: 3 RVKDAMQSDVITVKRTSSIHDAARVLRENRISGAPVVDEDGKLVGIISEGDIMRLIEVHS 62
Query: 184 --IRFIKP----------RFKAQYGELAGEKIPPFSMKLREAMIKGVITIMPEATIREAV 231
+ I P R K +Y E+A M++ E M V+T+ P A++ +A
Sbjct: 63 PSLNLIMPSPLDLLELPLRMKHEYDEIARGIRKAAVMRVEEIMTPKVVTVPPHASVSDAA 122
Query: 232 STMKDNNIDGLVVVDENNKVVGILTVKDLL 261
M+ ++I L V+DEN ++ GI+T D++
Sbjct: 123 ELMERHDIKRLPVIDENGRLAGIITRGDII 152
>sp|P50100|IMDH_METKA PUTATIVE INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (IMP DEHYDROGENASE)
(IMPDH) (IMPD) (ORFX) >gi|1002715|gb|AAA92086.1|
(U31567) similar to the inosine monophosphate
dehydrogenase from Pyrococcus furiosus (SwissProt
Accession Number P42851); orfX protein; Method:
conceptual translation supplied by author [Methanopyrus
kandleri]
Length = 172
Score = 75.3 bits (182), Expect = 1e-12
Identities = 43/130 (33%), Positives = 72/130 (55%), Gaps = 12/130 (9%)
Query: 132 VEEFMTKDVITLGPDDTVAKALATMRDHGISRIPVVDEEGKLEGLVTLHDLIIRFIKPRF 191
V E +DVIT P +T + MR+HGI + +V+E+ + G++T DL+I+ +
Sbjct: 6 VGEVARRDVITGSPTETAVEIAYKMREHGIGSVVIVNEKDEPIGIITERDLVIKVVSQ-- 63
Query: 192 KAQYGELAGEKIPPFSMKLREAMIKGVITIMPEATIREAVSTMKDNNIDGLVVVDENNKV 251
G+ P + R+ M + VIT+ + + EAV M D I L +VD+N K+
Sbjct: 64 --------GKN--PDEVIARDIMSQPVITVEEDMEVNEAVKLMVDKGIRRLPIVDDNGKL 113
Query: 252 VGILTVKDLL 261
+GI+T++D+L
Sbjct: 114 IGIVTMQDIL 123
>gi|11498454 conserved hypothetical protein [Archaeoglobus fulgidus]
>gi|7429331|pir||H69355 conserved hypothetical protein
MJ1225 homolog - Archaeoglobus fulgidus
>gi|2649753|gb|AAB90389.1| (AE001045) conserved
hypothetical protein [Archaeoglobus fulgidus]
Length = 284
Score = 74.9 bits (181), Expect = 1e-12
Identities = 51/188 (27%), Positives = 97/188 (51%), Gaps = 7/188 (3%)
Query: 79 VKPTDDLSHAAKLLLETDLRSLPVGENKAEILGVISDMALLERVVAEEFGKRKVEEFMTK 138
V +D L A + + E ++ P+ ++G+I++ +L+ + A ++MT
Sbjct: 92 VNESDSLEEAVETMFEKNVGGCPIVNKDDVVVGIITERDILKYLGANRSIDGVASDYMTS 151
Query: 139 DVITLGPDDTVAKALATMRDHGISRIPVVDEEGKLEGLVTLHDLIIRF-IKPRFK-AQYG 196
VITL P D++ +A+ TM + + RIP++D +G L GL+T+ +++ F F+ G
Sbjct: 152 SVITLRPKDSIERAMRTMIEKKLRRIPIID-DGILVGLITVREILRYFGTGEAFRMLTSG 210
Query: 197 ELAGEKIPPFSMKLRE---AMIKGVITIMPEATIREAVSTMKDNNIDGLVVVDENNKVVG 253
+ P S L + K ++T +I + VS+M + G+ ++ EN K+ G
Sbjct: 211 NIKDAIDKPISTILANDELLVYKDILTFPRNISISQLVSSMLEKGY-GVALIVENGKLEG 269
Query: 254 ILTVKDLL 261
I+T +DL+
Sbjct: 270 IITERDLI 277
Score = 72.2 bits (174), Expect = 1e-11
Identities = 48/147 (32%), Positives = 76/147 (51%), Gaps = 4/147 (2%)
Query: 134 EFMTKDVITLGPDDTVAKALATMRDHGISRIPVVDEEGK-LEGLVTLHDLIIRFIK-PRF 191
E TKDV TL P T+ AL M RIP+ D K LEG+++ D + F P+F
Sbjct: 3 EIATKDVFTLPPTSTLMNALKMMLRRNFRRIPIADPGTKRLEGIISATDFVNIFGGGPKF 62
Query: 192 KAQYGELAGEKIPPFSMKLREAMIKGVITIMPEATIREAVSTMKDNNIDGLVVVDENNKV 251
G G + + M + V+T+ ++ EAV TM + N+ G +V++++ V
Sbjct: 63 GLIKGRYGGNLSAAVNEVVETIMEREVVTVNESDSLEEAVETMFEKNVGGCPIVNKDDVV 122
Query: 252 VGILTVKDLL--LPISRMVEKEARFYL 276
VGI+T +D+L L +R ++ A Y+
Sbjct: 123 VGIITERDILKYLGANRSIDGVASDYM 149
>sp|Q58622|YC25_METJA HYPOTHETICAL PROTEIN MJ1225 >gi|2128050|pir||H64452 conserved
hypothetical protein MJ1225 - Methanococcus jannaschii
>gi|1591856|gb|AAB99228.1| (U67563) conserved
hypothetical protein [Methanococcus jannaschii]
Length = 280
Score = 74.5 bits (180), Expect = 2e-12
Identities = 60/244 (24%), Positives = 122/244 (49%), Gaps = 9/244 (3%)
Query: 19 INAPLSEAIGIIEKEDPDLILVFDDNVYKGVLTQDLIIRSHLKWDPTKAKVRDVYKPAPV 78
+NA ++ +GII D I+ F K L ++ R+ L VR++ + +
Sbjct: 41 VNAGNNKVVGIITSMD---IVDFMGGGSKYNLIREKHERNFLA--AINEPVREIMEENVI 95
Query: 79 -VKPTDDLSHAAKLLLETDLRSLPVGENKAEILGVISDMALLERVVAEEFGKRKVEEFMT 137
+K D+ A + L ++ P+ ++ +++ +I++ ++ ++ + +++++T
Sbjct: 96 TLKENADIDEAIETFLTKNVGGAPIVNDENQLISLITERDVIRALLDKIDENEVIDDYIT 155
Query: 138 KDVITLGPDDTVAKALATMRDHGISRIPVVDEEGKLEGLVTLHDLIIRFIKPRFKAQYGE 197
+DVI P + + TM +G R+PVV EG+L G++T D I+ + + + +
Sbjct: 156 RDVIVATPGERLKDVARTMVRNGFRRLPVV-SEGRLVGIITSTD-FIKLLGSDWAFNHMQ 213
Query: 198 LAGEKIPPFSMKLREAMIKGVITIMPEATIREAVSTMKDNNIDGLVVVDENNKVVGILTV 257
G ++++ E M + VIT +++ M N+I L VVDEN ++ GI+T
Sbjct: 214 -TGNVREITNVRMEEIMKRDVITAKEGDKLKKIAEIMVTNDIGALPVVDENLRIKGIITE 272
Query: 258 KDLL 261
KD+L
Sbjct: 273 KDVL 276
>pir||C72264 IMP dehydrogenase (EC 1.1.1.205) - Thermotoga maritima (strain
MSB8) >gi|4981907|gb|AAD36418.1|AE001789_3 (AE001789)
inosine-5'-monophosphate dehydrogenase [Thermotoga
maritima]
Length = 482
Score = 73.7 bits (178), Expect = 3e-12
Identities = 54/175 (30%), Positives = 88/175 (49%), Gaps = 20/175 (11%)
Query: 130 RKVEEFMTKDVITLGPDDTVAKALATMRDHGISRIPVVDEEGKLEGLVTLHDLIIRFIKP 189
+K E + D IT+ PD TV +A+ M ++ I +PVVDEEG+L GL+T D +RF K
Sbjct: 83 KKTENGIIYDPITVTPDMTVKEAIDLMAEYKIGGLPVVDEEGRLVGLLTNRD--VRFEK- 139
Query: 190 RFKAQYGELAGEKIPPFSMKLREAMI--KGVITIMPEATIREAVSTMKDNNIDGLVVVDE 247
S K+++ M + +I P+ ++ +A + + I+ L +V +
Sbjct: 140 ---------------NLSKKIKDLMTPREKLIVAPPDISLEKAKEILHQHRIEKLPLVSK 184
Query: 248 NNKVVGILTVKDLLLPISRMVEKEARFYLQLGGDASALSEFTRERIINDIKRFVD 302
+NK+VG++T+KD++ I L G A S T ER+ +K VD
Sbjct: 185 DNKLVGLITIKDIMSVIEHPNAARDEKGRLLVGAAVGTSPETMERVEKLVKAGVD 239
>pir||C75148 hypothetical protein PAB2118 - Pyrococcus abyssi (strain Orsay)
>gi|5457776|emb|CAB49266.1| (AJ248284) hypothetical
protein [Pyrococcus abyssi]
Length = 282
Score = 73.0 bits (176), Expect = 6e-12
Identities = 73/280 (26%), Positives = 125/280 (44%), Gaps = 28/280 (10%)
Query: 4 IQVQEVMTDRYAKIDINAPLSEAIGIIEKEDPDLILVFDDNVYKGVLTQDLIIRSHLKWD 63
++V+ +MT I + A + A+ I +K V + +G L + I+ L
Sbjct: 1 MKVKTIMTPNPVTITLPATRNYALDIFKKHKVRSFPVVNR---EGKLVGIISIKRVLTNP 57
Query: 64 PTKAKVRDVYKPAPVVKPTDDLSHAAKLLLETDLRSLPVGENKAEILGVISDMALLERVV 123
+ V + P VK DDL AA+L+LE D R + V +N+ + +G+++ ++ R +
Sbjct: 58 DEEQLAMLVKRDVPTVKENDDLKKAARLMLEHDYRRVVVVDNEGKPVGILTVGDIVRRYL 117
Query: 124 A--EEFGKRKVEEFMTKDVITLGPDDTVAKALATMRDHGISRIPVVDEEGKLEGLVTLHD 181
A E++ + ++E + + V + + AL + +PVVD+ G+L G++ D
Sbjct: 118 AKTEKYKEVEIEPYYQRHVSIVWKGTPLKAALKALLLSNAMALPVVDDNGELIGIIDETD 177
Query: 182 L-----IIRFIKPRFKAQYGE----------LAGEKIPPFSMKL-----REAMIKGVITI 221
L I+R +K A E L EK F ++L E M K VI
Sbjct: 178 LLRDSEIVRIMKSTELAASSEEEWILESHPTLLFEK---FELQLPNKPVEEIMTKDVIVA 234
Query: 222 MPEATIREAVSTMKDNNIDGLVVVDENNKVVGILTVKDLL 261
P T+ E M I+ L V+ +VG++ DLL
Sbjct: 235 TPHMTVYEVAKKMVKYRIEQLPVIKGEGDLVGLIRDFDLL 274
>gb|AAK43302.1| Conserved hypothetical protein [Sulfolobus solfataricus]
Length = 277
Score = 72.6 bits (175), Expect = 7e-12
Identities = 61/250 (24%), Positives = 127/250 (50%), Gaps = 29/250 (11%)
Query: 38 ILVFDDNVYKGVLTQDLI--IRSHLK--------WDPTKAKVRDVYKPAPV-VKPTDDLS 86
I+V ++ + + T+DL+ + S+ K + + + D P PV V T D
Sbjct: 35 IIVANEKIEGLLTTRDLLSTVESYCKDSCSQGDLYHISTTPIIDYMTPNPVTVYNTSDEF 94
Query: 87 HAAKLLLETDLRSLPVGENKAEILGVISD--MALLERVVAEEFGKRKVEEFMTKDVITLG 144
A +++ + SLPV + + +G++++ LL + + E F V+ FM+ V T+
Sbjct: 95 TAINIMVTRNFGSLPVVDINDKPVGIVTEREFLLLYKDLDEIF---PVKVFMSTKVQTIY 151
Query: 145 PDDTVAKALATMRDHGISRIPVVDEEGKLEGLVTLHDLIIRFIKPRFKAQYGELAGEKIP 204
+ + +A+ M G R+PV+D++ K+ G+VT+ + I + K A +K+
Sbjct: 152 KEVRLDQAVKLMLRRGFRRLPVIDDDNKVVGIVTVVNAIKQLAK----------AVDKLD 201
Query: 205 P---FSMKLREAMIKGVITIMPEATIREAVSTMKDNNIDGLVVVDENNKVVGILTVKDLL 261
P + +++ M+ ++TI A++ A + M I L++++++N + GI+T +DLL
Sbjct: 202 PDYFYGKVVKDVMVTNLVTIDELASVNRAAAEMIVKRIGSLLILNKDNTIRGIITERDLL 261
Query: 262 LPISRMVEKE 271
+ + ++ E
Sbjct: 262 IALHHILVME 271
>pir||H72780 hypothetical protein APE0233 - Aeropyrum pernix (strain K1)
>gi|5103625|dbj|BAA79146.1| (AP000058) 340aa long
hypothetical protein [Aeropyrum pernix]
Length = 340
Score = 72.6 bits (175), Expect = 7e-12
Identities = 52/194 (26%), Positives = 103/194 (52%), Gaps = 7/194 (3%)
Query: 79 VKPTDDLSHAAKLLLETDLRSLPVGENKAEILGVISDMALLERVVAEEFGKRKVEEFMTK 138
V +DDL ++++ + LPV + + GVI++ +L R+ F K KV ++MT
Sbjct: 152 VSVSDDLDTILRIMVGEGIGFLPVLYDDGTLHGVITERNILGRIADIPFDK-KVGDYMTA 210
Query: 139 DVITLGPDDTVAKALATMRDHGISRIPVVDEE-GKLEGLVTLHDLIIRFIKPRFKAQYGE 197
++ + P+ + +A+ +M +G R+ V+ G+++G++T D++ F +A
Sbjct: 211 TIVGVDPEAPLKEAMRSMVTYGFRRLLVISSSTGEIKGVITAKDIVAYF--GEHEAFKNA 268
Query: 198 LAGEKIPPFSMKLREAMIKGVITIMPEATIREAVSTMKDNNIDGLVVVDENNKVVGILTV 257
+G+ S+ + M V TI +A++ +A M + +D L+VVD + GI+T
Sbjct: 269 PSGKVSEAISIPVYMVMSPEVYTIDEKASVADAARRMVELGVDSLIVVD-GGEAKGIITE 327
Query: 258 KDLLLPISRMVEKE 271
+D+L ++ +VE E
Sbjct: 328 RDVL--VASVVEGE 339
>sp|O67820|IMDH_AQUAE INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (IMP DEHYDROGENASE) (IMPDH)
(IMPD) >gi|7427683|pir||H70473 IMP dehydrogenase (EC
1.1.1.205) - Aquifex aeolicus >gi|2984252|gb|AAC07779.1|
(AE000768) inosine monophosphate dehydrogenase [Aquifex
aeolicus]
Length = 490
Score = 71.8 bits (173), Expect = 1e-11
Identities = 51/140 (36%), Positives = 74/140 (52%), Gaps = 18/140 (12%)
Query: 124 AEEFGK-RKVEEFMTKDVITLGPDDTVAKALATMRDHGISRIPVVDEEGKLEGLVTLHDL 182
AEE K +K E M + +T+ PD V +AL M + IS +PVVDEE KL G++T DL
Sbjct: 83 AEEVEKVKKSESGMIINPVTVKPDTRVKEALDIMAKYKISGVPVVDEERKLIGILTNRDL 142
Query: 183 IIRFIKPRFKAQYGELAGEKIPPFSMKLREAMIKGVITIMPEA-TIREAVSTMKDNNIDG 241
RFIKP +S + E M K + PE T+ EA + I+
Sbjct: 143 --RFIKPE--------------DYSKPVSEFMTKENLITAPEGITLDEAEEIFRKYKIEK 186
Query: 242 LVVVDENNKVVGILTVKDLL 261
L +VD+ K+ G++T+KD++
Sbjct: 187 LPIVDKEGKIKGLITIKDIV 206
>pir||C71188 conserved hypothetical protein MJ1225 homolog - Pyrococcus
horikoshii >gi|3258215|dbj|BAA30898.1| (AP000007) 285aa
long hypothetical protein [Pyrococcus horikoshii]
Length = 285
Score = 71.0 bits (171), Expect = 2e-11
Identities = 73/283 (25%), Positives = 125/283 (43%), Gaps = 28/283 (9%)
Query: 1 MVGIQVQEVMTDRYAKIDINAPLSEAIGIIEKEDPDLILVFDDNVYKGVLTQDLIIRSHL 60
M+ ++V+ +MT I + A + A+ + +K V + +G L + ++ L
Sbjct: 1 MIWVRVKTIMTQNPVTITLPATRNYALELFKKYKVRSFPVVNK---EGKLVGIISVKRIL 57
Query: 61 KWDPTKAKVRDVYKPAPVVKPTDDLSHAAKLLLETDLRSLPVGENKAEILGVISDMALLE 120
+ V + PVVK D L AAKL+LE D R + V ++K + +G+++ ++
Sbjct: 58 VNPDEEQLAMLVKRDVPVVKENDTLKKAAKLMLEYDYRRVVVVDSKGKPVGILTVGDIIR 117
Query: 121 RVVA--EEFGKRKVEEFMTKDVITLGPDDTVAKALATMRDHGISRIPVVDEEGKLEGLVT 178
R A E++ ++E + + V + + AL + +PVVD EG L G+V
Sbjct: 118 RYFAKSEKYKGVEIEPYYQRYVSIVWEGTPLKAALKALLLSNSMALPVVDSEGNLVGIVD 177
Query: 179 LHDL-----IIRFIKPRFKAQYGE----------LAGEKIPPFSMKL-----REAMIKGV 218
DL I+R +K A E L EK F ++L E M + V
Sbjct: 178 ETDLLRDSEIVRIMKSTELAASSEEEWILESHPTLLFEK---FELQLPNKPVAEIMTRDV 234
Query: 219 ITIMPEATIREAVSTMKDNNIDGLVVVDENNKVVGILTVKDLL 261
I P T+ E M +I+ L V+ ++G++ DLL
Sbjct: 235 IVATPHMTVHEVALKMAKYSIEQLPVIRGEGDLIGLIRDFDLL 277
>pir||B72265 hypothetical protein TM1354 - Thermotoga maritima (strain MSB8)
>gi|4981914|gb|AAD36425.1|AE001789_10 (AE001789)
inosine-5-monophosphate dehydrogenase-related protein
[Thermotoga maritima]
Length = 321
Score = 71.0 bits (171), Expect = 2e-11
Identities = 37/105 (35%), Positives = 62/105 (58%), Gaps = 1/105 (0%)
Query: 79 VKPTDDLSHAAKLLLETDLRSLPVGENKAEILGVISDMALLERVVAEEFGKRKVEEFMTK 138
V P L H +++ + +PV ++K ++G++S ++ + + + K VE+ MTK
Sbjct: 29 VTPDKTLLHVKEIMRIKRISGVPVVDDKKRVVGIVSLEDII-KALEGSYIKDSVEKRMTK 87
Query: 139 DVITLGPDDTVAKALATMRDHGISRIPVVDEEGKLEGLVTLHDLI 183
+V+ L DT+ A+ T +G R PVVD+EGKL G+VT HD+I
Sbjct: 88 NVVCLKETDTLQDAVKTFEKYGYGRFPVVDDEGKLVGIVTKHDII 132
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.321 0.141 0.394
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 138639362
Number of Sequences: 2977
Number of extensions: 5939473
Number of successful extensions: 17748
Number of sequences better than 1.0e-10: 31
Number of HSP's better than 0.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 17557
Number of HSP's gapped (non-prelim): 77
length of query: 392
length of database: 189,106,746
effective HSP length: 57
effective length of query: 335
effective length of database: 154,992,987
effective search space: 51922650645
effective search space used: 51922650645
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 166 (69.1 bits)