BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB0966 (PAB0966) DE:SIGNAL PEPTIDASE
(155 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||A75058 signal peptidase PAB0966 - Pyrococcus abyssi (strain... 313 8e-85
pir||B71174 probable signal peptidase subunit - Pyrococcus horik... 237 6e-62
gb|AAD19813.1| (AE001574) SPC 21-kDa-like [Drosophila melanogast... 78 7e-14
gb|AAC36354.1| (AF090315) signal peptidase complex 18 kDa subuni... 72 3e-12
sp|O75957|SPC4_HUMAN MICROSOMAL SIGNAL PEPTIDASE 18 KDA SUBUNIT ... 72 3e-12
gi|7657609 signal peptidase complex (18kD) [Homo sapiens] >gi|13... 72 3e-12
gi|11433173 signal peptidase complex (18kD) [Homo sapiens] 72 3e-12
sp|P13679|SPC3_CANFA MICROSOMAL SIGNAL PEPTIDASE 21 KD SUBUNIT (... 72 4e-12
dbj|BAA76439.1| (AB022714) signal peptidase 21kDa subunit [Rattu... 72 4e-12
gi|9910550 sid2895p [Mus musculus] >gi|5931559|dbj|BAA84690.1| (... 71 7e-12
gb|AAF59551.1| (AC024812) contains similarity to SW:SPC4_CANFA [... 70 1e-11
sp|P42667|SPC4_RAT MICROSOMAL SIGNAL PEPTIDASE 18 KDA SUBUNIT (S... 70 2e-11
>pir||A75058 signal peptidase PAB0966 - Pyrococcus abyssi (strain Orsay)
>gi|5458871|emb|CAB50358.1| (AJ248287) SIGNAL PEPTIDASE
[Pyrococcus abyssi]
Length = 155
Score = 313 bits (793), Expect = 8e-85
Identities = 155/155 (100%), Positives = 155/155 (100%)
Query: 1 MDERLKEILSMVLTVILVFSVYFGLRVVLHTKTPLVVVASGSMRPVFYPGDVVLLKGVKP 60
MDERLKEILSMVLTVILVFSVYFGLRVVLHTKTPLVVVASGSMRPVFYPGDVVLLKGVKP
Sbjct: 1 MDERLKEILSMVLTVILVFSVYFGLRVVLHTKTPLVVVASGSMRPVFYPGDVVLLKGVKP 60
Query: 61 EEIKVGDVIVYKSAFSKYPIIHRVRGIKQVYINGKPQLCFITWGDNNPVPDLYELPNGGI 120
EEIKVGDVIVYKSAFSKYPIIHRVRGIKQVYINGKPQLCFITWGDNNPVPDLYELPNGGI
Sbjct: 61 EEIKVGDVIVYKSAFSKYPIIHRVRGIKQVYINGKPQLCFITWGDNNPVPDLYELPNGGI 120
Query: 121 IDCVPSYAVEAKALIVFPKIGIISIKVRELLGIGG 155
IDCVPSYAVEAKALIVFPKIGIISIKVRELLGIGG
Sbjct: 121 IDCVPSYAVEAKALIVFPKIGIISIKVRELLGIGG 155
>pir||B71174 probable signal peptidase subunit - Pyrococcus horikoshii
>gi|3256996|dbj|BAA29679.1| (AP000002) 154aa long
hypothetical signal peptidase subunit [Pyrococcus
horikoshii]
Length = 154
Score = 237 bits (598), Expect = 6e-62
Identities = 112/155 (72%), Positives = 135/155 (86%), Gaps = 1/155 (0%)
Query: 1 MDERLKEILSMVLTVILVFSVYFGLRVVLHTKTPLVVVASGSMRPVFYPGDVVLLKGVKP 60
MDE+ KE++S +L ++L ++YFGLRV LHT+TPLVVV SGSM PVF+ GDVVLL+GV+P
Sbjct: 1 MDEKGKEVISTLLIILLTLALYFGLRVALHTETPLVVVVSGSMEPVFHRGDVVLLEGVRP 60
Query: 61 EEIKVGDVIVYKSAFSKYPIIHRVRGIKQVYINGKPQLCFITWGDNNPVPDLYELPNGGI 120
EE++VGDVIVY+S S+YPIIHRVRGIK +YINGK +LCFITWGD+NPVPD+Y P GI
Sbjct: 61 EEVRVGDVIVYRSIISRYPIIHRVRGIKYIYINGKRELCFITWGDHNPVPDIYYTPE-GI 119
Query: 121 IDCVPSYAVEAKALIVFPKIGIISIKVRELLGIGG 155
+DCVP+ AVEAKAL VFP+IGIISIKVRELLG GG
Sbjct: 120 LDCVPAEAVEAKALAVFPRIGIISIKVRELLGFGG 154
>gb|AAD19813.1| (AE001574) SPC 21-kDa-like [Drosophila melanogaster]
>gi|5679033|gb|AAD46829.1|AF160889_1 (AF160889)
BcDNA.GM04682 [Drosophila melanogaster]
>gi|7298894|gb|AAF54100.1| (AE003674) BG:DS00004.11 gene
product [Drosophila melanogaster]
Length = 185
Score = 77.6 bits (188), Expect = 7e-14
Identities = 51/149 (34%), Positives = 82/149 (54%), Gaps = 9/149 (6%)
Query: 3 ERLKEILSMVLTVILVFSVYFGLRVVLHTKTPLVVVASGSMRPVFYPGDVVLLKGVKPEE 62
+ L ++LS + V ++ GL VV +++P+VVV SGSM P F+ GD++ L K E
Sbjct: 23 QSLYQVLSFAMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLTNYKEEP 82
Query: 63 IKVGDVIVYKSAFSKYPIIHRVRGIKQVYINGKPQLCFITWGDNNPVPD--LYELPNGGI 120
++VG+++V+K PI+HRV +++ + F+T GDNN V D LY PN
Sbjct: 83 VRVGEIVVFKVEGRDIPIVHRV---IKLHEKEDGSVKFLTKGDNNNVDDRGLY-APNQ-- 136
Query: 121 IDCVPSYAVEAKALIVFPKIGIISIKVRE 149
+ + +A P +GII+I + E
Sbjct: 137 -LWLTKKDIVGRARGFLPYVGIITIFMNE 164
>gb|AAC36354.1| (AF090315) signal peptidase complex 18 kDa subunit [Homo sapiens]
Length = 167
Score = 72.2 bits (174), Expect = 3e-12
Identities = 46/143 (32%), Positives = 78/143 (54%), Gaps = 5/143 (3%)
Query: 7 EILSMVLTVILVFSVYFGLRVVLHTKTPLVVVASGSMRPVFYPGDVVLLKGVKPEEIKVG 66
++L+ + V ++ GL V+ +++P+VVV SGSM P F+ GD++ L + I+VG
Sbjct: 9 QVLNFGMIVSSALMIWKGLMVITGSESPIVVVLSGSMEPAFHRGDLLFLTNRVEDPIRVG 68
Query: 67 DVIVYKSAFSKYPIIHRVRGIKQVYINGKPQLCFITWGDNNPVPDLYELPNGGIIDCVPS 126
+++V++ + PI+HRV I + NG + F+T GDNN V D G +
Sbjct: 69 EIVVFRIEGREIPIVHRVLKIHEKQ-NG--HIKFLTKGDNNAVDDRGLYKQGQ--HWLEK 123
Query: 127 YAVEAKALIVFPKIGIISIKVRE 149
V +A P IGI++I + +
Sbjct: 124 KDVVGRARGFVPYIGIVTILMND 146
>sp|O75957|SPC4_HUMAN MICROSOMAL SIGNAL PEPTIDASE 18 KDA SUBUNIT (SPC18) (ENDOPEPTIDASE
SP18) >gi|4378718|gb|AAD19640.1| (AF108945) signal
peptidase 18 kDa subunit [Homo sapiens]
Length = 179
Score = 72.2 bits (174), Expect = 3e-12
Identities = 46/143 (32%), Positives = 78/143 (54%), Gaps = 5/143 (3%)
Query: 7 EILSMVLTVILVFSVYFGLRVVLHTKTPLVVVASGSMRPVFYPGDVVLLKGVKPEEIKVG 66
++L+ + V ++ GL V+ +++P+VVV SGSM P F+ GD++ L + I+VG
Sbjct: 21 QVLNFGMIVSSALMIWKGLMVITGSESPIVVVLSGSMEPAFHRGDLLFLTNRVEDPIRVG 80
Query: 67 DVIVYKSAFSKYPIIHRVRGIKQVYINGKPQLCFITWGDNNPVPDLYELPNGGIIDCVPS 126
+++V++ + PI+HRV I + NG + F+T GDNN V D G +
Sbjct: 81 EIVVFRIEGREIPIVHRVLKIHEKQ-NG--HIKFLTKGDNNAVDDRGLYKQGQ--HWLEK 135
Query: 127 YAVEAKALIVFPKIGIISIKVRE 149
V +A P IGI++I + +
Sbjct: 136 KDVVGRARGFVPYIGIVTILMND 158
>gi|7657609 signal peptidase complex (18kD) [Homo sapiens]
>gi|134794|sp|P21378|SPC4_BOVIN MICROSOMAL SIGNAL
PEPTIDASE 18 KDA SUBUNIT (SPC18) (ENDOPEPTIDASE SP18)
>gi|108137|pir||A35309 signal peptidase (EC 3.4.99.-)
18K chain - dog >gi|164082|gb|AAA30895.1| (J05466)
microsomal signal peptidase complex [Canis familiaris]
>gi|4335939|gb|AAD17526.1| (AF061737) microsomal signal
peptidase [Homo sapiens]
>gi|6979934|gb|AAF34660.1|AF221669_1 (AF221669)
endopeptidase SP18 [Bos taurus]
Length = 179
Score = 72.2 bits (174), Expect = 3e-12
Identities = 46/143 (32%), Positives = 78/143 (54%), Gaps = 5/143 (3%)
Query: 7 EILSMVLTVILVFSVYFGLRVVLHTKTPLVVVASGSMRPVFYPGDVVLLKGVKPEEIKVG 66
++L+ + V ++ GL V+ +++P+VVV SGSM P F+ GD++ L + I+VG
Sbjct: 21 QVLNFGMIVSSALMIWKGLMVITGSESPIVVVLSGSMEPAFHRGDLLFLTNRVEDPIRVG 80
Query: 67 DVIVYKSAFSKYPIIHRVRGIKQVYINGKPQLCFITWGDNNPVPDLYELPNGGIIDCVPS 126
+++V++ + PI+HRV I + NG + F+T GDNN V D G +
Sbjct: 81 EIVVFRIEGREIPIVHRVLKIHEKQ-NG--HIKFLTKGDNNAVDDRGLYKQGQ--HWLEK 135
Query: 127 YAVEAKALIVFPKIGIISIKVRE 149
V +A P IGI++I + +
Sbjct: 136 KDVVGRARGFVPYIGIVTILMND 158
>gi|11433173 signal peptidase complex (18kD) [Homo sapiens]
Length = 205
Score = 72.2 bits (174), Expect = 3e-12
Identities = 46/143 (32%), Positives = 78/143 (54%), Gaps = 5/143 (3%)
Query: 7 EILSMVLTVILVFSVYFGLRVVLHTKTPLVVVASGSMRPVFYPGDVVLLKGVKPEEIKVG 66
++L+ + V ++ GL V+ +++P+VVV SGSM P F+ GD++ L + I+VG
Sbjct: 47 QVLNFGMIVSSALMIWKGLMVITGSESPIVVVLSGSMEPAFHRGDLLFLTNRVEDPIRVG 106
Query: 67 DVIVYKSAFSKYPIIHRVRGIKQVYINGKPQLCFITWGDNNPVPDLYELPNGGIIDCVPS 126
+++V++ + PI+HRV I + NG + F+T GDNN V D G +
Sbjct: 107 EIVVFRIEGREIPIVHRVLKIHEKQ-NG--HIKFLTKGDNNAVDDRGLYKQGQ--HWLEK 161
Query: 127 YAVEAKALIVFPKIGIISIKVRE 149
V +A P IGI++I + +
Sbjct: 162 KDVVGRARGFVPYIGIVTILMND 184
>sp|P13679|SPC3_CANFA MICROSOMAL SIGNAL PEPTIDASE 21 KD SUBUNIT (SPC21)
>gi|89064|pir||A34229 signal peptidase (EC 3.4.99.-) 21K
chain - dog >gi|164084|gb|AAA30896.1| (J05069) signal
peptidase 21 kDa subunit [Canis familiaris]
Length = 192
Score = 71.8 bits (173), Expect = 4e-12
Identities = 36/105 (34%), Positives = 62/105 (58%), Gaps = 3/105 (2%)
Query: 7 EILSMVLTVILVFSVYFGLRVVLHTKTPLVVVASGSMRPVFYPGDVVLLKGVKPEEIKVG 66
++L+ + V ++ GL V+ +++P+VVV SGSM P F+ GD++ L + + I+ G
Sbjct: 33 QVLNFAMIVSSALMIWKGLIVLTGSESPIVVVLSGSMEPAFHRGDLLFLTNFREDPIRAG 92
Query: 67 DVIVYKSAFSKYPIIHRVRGIKQVYINGKPQLCFITWGDNNPVPD 111
+++V+K PI+HRV +V+ + F+T GDNN V D
Sbjct: 93 EIVVFKVEGRDIPIVHRV---IKVHEKDNGDIKFLTKGDNNEVDD 134
>dbj|BAA76439.1| (AB022714) signal peptidase 21kDa subunit [Rattus norvegicus]
Length = 192
Score = 71.8 bits (173), Expect = 4e-12
Identities = 36/105 (34%), Positives = 62/105 (58%), Gaps = 3/105 (2%)
Query: 7 EILSMVLTVILVFSVYFGLRVVLHTKTPLVVVASGSMRPVFYPGDVVLLKGVKPEEIKVG 66
++L+ + V ++ GL V+ +++P+VVV SGSM P F+ GD++ L + + I+ G
Sbjct: 33 QVLNFAMIVSSALMIWKGLIVLTGSESPIVVVLSGSMEPAFHRGDLLFLTNFREDPIRAG 92
Query: 67 DVIVYKSAFSKYPIIHRVRGIKQVYINGKPQLCFITWGDNNPVPD 111
+++V+K PI+HRV +V+ + F+T GDNN V D
Sbjct: 93 EIVVFKVEGRDIPIVHRV---IKVHEKDNGDIKFLTKGDNNEVDD 134
>gi|9910550 sid2895p [Mus musculus] >gi|5931559|dbj|BAA84690.1| (AB025405)
sid2895p [Mus musculus]
Length = 179
Score = 71.0 bits (171), Expect = 7e-12
Identities = 43/143 (30%), Positives = 77/143 (53%), Gaps = 5/143 (3%)
Query: 7 EILSMVLTVILVFSVYFGLRVVLHTKTPLVVVASGSMRPVFYPGDVVLLKGVKPEEIKVG 66
++L+ + V ++ GL V+ +++P+VVV SGSM P F+ GD++ L + I+VG
Sbjct: 21 QVLNFGMIVSSALMIWKGLMVITGSESPIVVVLSGSMEPAFHRGDLLFLTNRVEDPIRVG 80
Query: 67 DVIVYKSAFSKYPIIHRVRGIKQVYINGKPQLCFITWGDNNPVPDLYELPNGGIIDCVPS 126
+++V++ + PI+HRV +++ + F+T GDNN V D G +
Sbjct: 81 EIVVFRIEGREIPIVHRV---LKIHEKQDGHIKFLTKGDNNAVDDRGLYKQGQ--HWLEK 135
Query: 127 YAVEAKALIVFPKIGIISIKVRE 149
V +A P IGI++I + +
Sbjct: 136 KDVVGRARGFVPYIGIVTILMND 158
>gb|AAF59551.1| (AC024812) contains similarity to SW:SPC4_CANFA [Caenorhabditis
elegans]
Length = 183
Score = 70.2 bits (169), Expect = 1e-11
Identities = 37/105 (35%), Positives = 59/105 (55%), Gaps = 3/105 (2%)
Query: 7 EILSMVLTVILVFSVYFGLRVVLHTKTPLVVVASGSMRPVFYPGDVVLLKGVKPEEIKVG 66
+ L+ + V ++ G+ V+ + +P+VVV SGSM P FY GD++LL + ++VG
Sbjct: 24 QCLNFAMVVSSALMIWKGMMVITGSDSPVVVVLSGSMEPAFYRGDLLLLTNDLEDPVRVG 83
Query: 67 DVIVYKSAFSKYPIIHRVRGIKQVYINGKPQLCFITWGDNNPVPD 111
D+ V+K + PI+HRV +V+ +T GDNN V D
Sbjct: 84 DITVFKVEGREIPIVHRV---IKVHEKSADNTKILTKGDNNQVDD 125
>sp|P42667|SPC4_RAT MICROSOMAL SIGNAL PEPTIDASE 18 KDA SUBUNIT (SPC18) (ENDOPEPTIDASE
SP18) >gi|7435856|pir||I57489 signal peptidase - rat
>gi|206978|gb|AAA64738.1| (L11319) signal peptidase
[Rattus norvegicus]
Length = 179
Score = 69.9 bits (168), Expect = 2e-11
Identities = 42/143 (29%), Positives = 77/143 (53%), Gaps = 5/143 (3%)
Query: 7 EILSMVLTVILVFSVYFGLRVVLHTKTPLVVVASGSMRPVFYPGDVVLLKGVKPEEIKVG 66
++L+ + V ++ GL ++ +++P+VVV SGSM P F+ GD++ L + I+VG
Sbjct: 21 QVLNFGMIVSSALMIWKGLMLITGSESPIVVVLSGSMEPAFHRGDLLFLTNRVEDPIRVG 80
Query: 67 DVIVYKSAFSKYPIIHRVRGIKQVYINGKPQLCFITWGDNNPVPDLYELPNGGIIDCVPS 126
+++V++ + PI+HRV +++ + F+T GDNN V D G +
Sbjct: 81 EIVVFRIEGREIPIVHRV---LKIHEKQDGHIKFLTKGDNNAVDDRGLYKQGQ--HWLEK 135
Query: 127 YAVEAKALIVFPKIGIISIKVRE 149
V +A P IGI++I + +
Sbjct: 136 KDVVGRARGFVPYIGIVTILMND 158
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.325 0.147 0.436
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60352562
Number of Sequences: 2977
Number of extensions: 2673238
Number of successful extensions: 4780
Number of sequences better than 1.0e-10: 12
Number of HSP's better than 0.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 4767
Number of HSP's gapped (non-prelim): 12
length of query: 155
length of database: 189,106,746
effective HSP length: 49
effective length of query: 106
effective length of database: 159,780,883
effective search space: 16936773598
effective search space used: 16936773598
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (22.0 bits)
S2: 162 (67.5 bits)