BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB1029 (PAB1029) DE:NA+/CA+ EXCHANGING PROTEIN RELATED
(314 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||C75003 na+/ca+ exchanging protein related PAB1029 - Pyrococ... 586 e-167
pir||D71159 probable Na+/Ca2+-exchanging protein - Pyrococcus ho... 497 e-140
sp|Q57556|Y091_METJA HYPOTHETICAL PROTEIN MJ0091 >gi|2129153|pir... 186 2e-46
dbj|BAB04184.1| (AP001508) unknown conserved protein in others [... 183 2e-45
pir||H82064 conserved hypothetical protein VC2522 [imported] - V... 173 2e-42
pir||S74922 hypothetical protein slr0681 - Synechocystis sp. (st... 170 2e-41
pir||E70306 conserved hypothetical protein aq_066 - Aquifex aeol... 169 5e-41
pir||B72342 conserved hypothetical protein - Thermotoga maritima... 168 6e-41
sp|P45394|YRBG_ECOLI HYPOTHETICAL 34.7 KD PROTEIN IN MURA-RPON I... 165 5e-40
pir||H69020 probable Na+/Ca2+,K+-exchanging protein - Methanobac... 156 3e-37
gb|AAG18939.1| (AE004995) cation antiporter; Caa [Halobacterium ... 153 2e-36
pir||E69009 cation antiporter - Methanobacterium thermoautotroph... 142 6e-33
pir||A71250 conserved hypothetical integral membrane protein TP1... 132 5e-30
pir||D70120 probable Na+/Ca2+-exchanging protein - Lyme disease ... 120 3e-26
pir||T45258 hypothetical protein [imported] - Methanobacterium t... 98 2e-19
pir||S68978 Na+/Ca2+,K+-exchanging protein homolog - Methanobact... 94 2e-18
gb|AAG20377.1| (AE005111) Na+/Ca2+-exchanging protein; Nce [Halo... 94 3e-18
gb|AAK41422.1| Na(+)/Ca(2+) exchanging protein related [Sulfolob... 79 6e-14
gb|AAK43291.1| Conserved hypothetical protein [Sulfolobus solfat... 78 1e-13
emb|CAC12320.1| (AL445066) conserved hypothetical membrane prote... 74 2e-12
dbj|BAB06586.1| (AP001516) cation antiporter (Na+/Ca2+) [Bacillu... 70 4e-11
>pir||C75003 na+/ca+ exchanging protein related PAB1029 - Pyrococcus abyssi
(strain Orsay) >gi|5458979|emb|CAB50465.1| (AJ248288)
NA+/CA+ EXCHANGING PROTEIN RELATED [Pyrococcus abyssi]
Length = 314
Score = 586 bits (1495), Expect = e-167
Identities = 314/314 (100%), Positives = 314/314 (100%)
Query: 1 MEVAIVTAVFILGLILLIKGSDIFVNAATRIAETFGVSEFLIALVLASIATTLPEATVSA 60
MEVAIVTAVFILGLILLIKGSDIFVNAATRIAETFGVSEFLIALVLASIATTLPEATVSA
Sbjct: 1 MEVAIVTAVFILGLILLIKGSDIFVNAATRIAETFGVSEFLIALVLASIATTLPEATVSA 60
Query: 61 ISSYKGNSGIALGNAVGSALANIALILGISAMITPLKVDEVANENSLIMLGVTLYAWLLM 120
ISSYKGNSGIALGNAVGSALANIALILGISAMITPLKVDEVANENSLIMLGVTLYAWLLM
Sbjct: 61 ISSYKGNSGIALGNAVGSALANIALILGISAMITPLKVDEVANENSLIMLGVTLYAWLLM 120
Query: 121 INGEISRIEGLTLVLIYGAFLYYLYRKHVKLEEIEEESRGNVIKDIAILFLSGGMVILGA 180
INGEISRIEGLTLVLIYGAFLYYLYRKHVKLEEIEEESRGNVIKDIAILFLSGGMVILGA
Sbjct: 121 INGEISRIEGLTLVLIYGAFLYYLYRKHVKLEEIEEESRGNVIKDIAILFLSGGMVILGA 180
Query: 181 ELVVDSAVKIARGAGIPEVVIGVTLVSIGTSLPELANSLTAALKGIHNVSVGNIIGADII 240
ELVVDSAVKIARGAGIPEVVIGVTLVSIGTSLPELANSLTAALKGIHNVSVGNIIGADII
Sbjct: 181 ELVVDSAVKIARGAGIPEVVIGVTLVSIGTSLPELANSLTAALKGIHNVSVGNIIGADII 240
Query: 241 DILMVIGIASIIRPIKVDPSIVKVTMPITVLVMAILTVSLFRNNKVGRKTAVTLLLVYSI 300
DILMVIGIASIIRPIKVDPSIVKVTMPITVLVMAILTVSLFRNNKVGRKTAVTLLLVYSI
Sbjct: 241 DILMVIGIASIIRPIKVDPSIVKVTMPITVLVMAILTVSLFRNNKVGRKTAVTLLLVYSI 300
Query: 301 FLYLLAQGKVYIPG 314
FLYLLAQGKVYIPG
Sbjct: 301 FLYLLAQGKVYIPG 314
>pir||D71159 probable Na+/Ca2+-exchanging protein - Pyrococcus horikoshii
>gi|3256878|dbj|BAA29561.1| (AP000002) 325aa long
hypothetical Na(+)/Ca(2+)-exchanging protein [Pyrococcus
horikoshii]
Length = 325
Score = 497 bits (1265), Expect = e-140
Identities = 258/306 (84%), Positives = 281/306 (91%)
Query: 9 VFILGLILLIKGSDIFVNAATRIAETFGVSEFLIALVLASIATTLPEATVSAISSYKGNS 68
+F GL+LLIKGSDIFV AATRIAE F VSEFLIALVLAS+ATTLPE TVSAISSY+GNS
Sbjct: 20 IFSAGLLLLIKGSDIFVEAATRIAEAFKVSEFLIALVLASVATTLPEVTVSAISSYRGNS 79
Query: 69 GIALGNAVGSALANIALILGISAMITPLKVDEVANENSLIMLGVTLYAWLLMINGEISRI 128
GIA+GNAVGSALANIALIL ISAMI PL VD++A+ENSLIM+GVT YAWLLM NGEISRI
Sbjct: 80 GIAIGNAVGSALANIALILAISAMIMPLNVDKIASENSLIMVGVTFYAWLLMSNGEISRI 139
Query: 129 EGLTLVLIYGAFLYYLYRKHVKLEEIEEESRGNVIKDIAILFLSGGMVILGAELVVDSAV 188
EGLTLVLIY AFLYYLYRKHVKLEE+E++SR NV +D+ ILFLSGGMVILGAELVVDSAV
Sbjct: 140 EGLTLVLIYAAFLYYLYRKHVKLEEVEKKSRCNVTRDVLILFLSGGMVILGAELVVDSAV 199
Query: 189 KIARGAGIPEVVIGVTLVSIGTSLPELANSLTAALKGIHNVSVGNIIGADIIDILMVIGI 248
KIAR GIPEVVIGVTLVSIGTSLPE ANSLTA LK I NVSVGNIIGADI+DILMVIGI
Sbjct: 200 KIARAIGIPEVVIGVTLVSIGTSLPEFANSLTATLKKIPNVSVGNIIGADILDILMVIGI 259
Query: 249 ASIIRPIKVDPSIVKVTMPITVLVMAILTVSLFRNNKVGRKTAVTLLLVYSIFLYLLAQG 308
AS+IRPI+VDPSIVK+ MPIT+LVM ILTVSLFRNNK+GRKTAVTLL++YS F+YLL QG
Sbjct: 260 ASMIRPIRVDPSIVKIVMPITLLVMIILTVSLFRNNKIGRKTAVTLLIIYSAFIYLLTQG 319
Query: 309 KVYIPG 314
KVYIPG
Sbjct: 320 KVYIPG 325
Score = 81.9 bits (199), Expect = 9e-15
Identities = 41/144 (28%), Positives = 88/144 (60%), Gaps = 8/144 (5%)
Query: 166 IAILFLSGGMVIL--GAELVVDSAVKIARGAGIPEVVIGVTLVSIGTSLPELANSLTAAL 223
+ IL S G+++L G+++ V++A +IA + E +I + L S+ T+LPE+ S ++
Sbjct: 16 LEILIFSAGLLLLIKGSDIFVEAATRIAEAFKVSEFLIALVLASVATTLPEVTVSAISSY 75
Query: 224 KGIHNVSVGNIIGADIIDILMVIGIASIIRPIKVDPSIVKVTMPITVLVMAILTVS--LF 281
+G +++GN +G+ + +I +++ I+++I P+ VD K+ +++++ + + L
Sbjct: 76 RGNSGIAIGNAVGSALANIALILAISAMIMPLNVD----KIASENSLIMVGVTFYAWLLM 131
Query: 282 RNNKVGRKTAVTLLLVYSIFLYLL 305
N ++ R +TL+L+Y+ FLY L
Sbjct: 132 SNGEISRIEGLTLVLIYAAFLYYL 155
>sp|Q57556|Y091_METJA HYPOTHETICAL PROTEIN MJ0091 >gi|2129153|pir||C64311
Na+/Ca2+-exchanging protein - Methanococcus jannaschii
>gi|1590872|gb|AAB98072.1| (U67466) Na+/Ca+ exchanger
protein, putative [Methanococcus jannaschii]
Length = 302
Score = 186 bits (468), Expect = 2e-46
Identities = 112/300 (37%), Positives = 181/300 (60%), Gaps = 7/300 (2%)
Query: 10 FILGLILLIKGSDIFVNAATRIAETFGVSEFLIALVLASIATTLPEATVSAISSYKGNSG 69
F+LGLILL GSD FV + RIA F VS F+I + +I T+LPE SA +SY G
Sbjct: 9 FLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPG 68
Query: 70 IALGNAVGSALANIALILGISAMITPLKVDEVANENSLIMLGVTLYAWLLMINGEISRIE 129
I++GNA+GS + NI L+LG+SA+I+P+ VD+ +N L+ L ++A ++ I+G S I+
Sbjct: 69 ISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDG-FSWID 127
Query: 130 GLTLVLIYGAFLYYLYRK-HVKLEEIEEESRGNVIKDIAILFLSGGMVILGAELVVDSAV 188
G+ L++++ +L + + ++EE +++ +V+ + +L + V++GAEL VD A
Sbjct: 128 GVVLLILFIIYLRWTVKNGSAEIEENNDKNNPSVVFSLVLLIIGLIGVLVGAELFVDGAK 187
Query: 189 KIARGAGIPEVVIGVTLVSIGTSLPELANSLTAALKGIHNVSVGNIIGADIIDILMVIGI 248
KIA I + VIG TLV+ GTSLPEL SL AA + + + +GN+IG++I DI + +
Sbjct: 188 KIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAV 247
Query: 249 ASIIRPIKVDPSIVKVTMPITVLVMAILTVSLFRNNKVGRKTAVTLLLVYSIFLYLLAQG 308
S+ + + V M + V +M++L + +K+GR + L +Y I + L G
Sbjct: 248 GSLFMHLPAE----NVQMAVLV-IMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLRMG 302
>dbj|BAB04184.1| (AP001508) unknown conserved protein in others [Bacillus
halodurans]
Length = 318
Score = 183 bits (460), Expect = 2e-45
Identities = 112/304 (36%), Positives = 177/304 (57%), Gaps = 15/304 (4%)
Query: 9 VFILGLILLIKGSDIFVNAATRIAETFGVSEFLIALVLASIATTLPEATVSAISSYKGNS 68
+ +LG LLIKG+D FV+ ++ IA VS LI L + + T+ PEAT S I++ GN
Sbjct: 5 LLLLGFALLIKGADFFVDGSSSIARLLNVSPLLIGLTIVAFGTSSPEATASIIAALNGNP 64
Query: 69 GIALGNAVGSALANIALILGISAMITPLKVDEVANENSL---IMLGVTLYAWL--LMING 123
+ALGN +GS + NI L++G++A+++PL V + ++ + LY ++ MI G
Sbjct: 65 DVALGNVIGSNMFNITLVVGLTALLSPLIVTNATLRKEIPFTLLASIALYIFINDQMIEG 124
Query: 124 EI----SRIEGLTLVLIYGAFLYYLY---RKHVKLEEIEEES--RGNVIKDIAILFLSGG 174
+ SR EGL L+LI+ FLYY++ R + ++I ++ + K+I + L
Sbjct: 125 AVESTLSRSEGLILLLIFCVFLYYIFEVARTSPREQKIVQDFAIKPTWRKNIFLSILGLA 184
Query: 175 MVILGAELVVDSAVKIARGAGIPEVVIGVTLVSIGTSLPELANSLTAALKGIHNVSVGNI 234
M+I G ELV+ + IA G+ E ++G+T+V+IGTSLPEL SLTAALK +++GNI
Sbjct: 185 MIIGGGELVIRHSTAIAFSHGMSETLVGLTIVAIGTSLPELVTSLTAALKKESEIALGNI 244
Query: 235 IGADIIDILMVIGIASIIRPIKVDPSIVKVTMPITVLVMAILTVSLFRNNKVGRKTAVTL 294
+G+ I +I V+G A+ I P+ VD +V + + L + +L S R VG+ + L
Sbjct: 245 VGSSIFNIFFVLGTAATITPMHVDSRVVVDLLLLIFLTLLLLVFSRTRYT-VGKYEGLIL 303
Query: 295 LLVY 298
Y
Sbjct: 304 ASFY 307
Score = 88.9 bits (217), Expect = 7e-17
Identities = 47/147 (31%), Positives = 90/147 (60%), Gaps = 11/147 (7%)
Query: 168 ILFLSGGMVILGAELVVDSAVKIARGAGIPEVVIGVTLVSIGTSLPELANSLTAALKGIH 227
+L L ++I GA+ VD + IAR + ++IG+T+V+ GTS PE S+ AAL G
Sbjct: 5 LLLLGFALLIKGADFFVDGSSSIARLLNVSPLLIGLTIVAFGTSSPEATASIIAALNGNP 64
Query: 228 NVSVGNIIGADIIDILMVIGIASIIRPIKVDPSIVKVTMPITVLVMAILTVSLFRNNKV- 286
+V++GN+IG+++ +I +V+G+ +++ P+ V + ++ +P T+L A + + +F N+++
Sbjct: 65 DVALGNVIGSNMFNITLVVGLTALLSPLIVTNATLRKEIPFTLL--ASIALYIFINDQMI 122
Query: 287 --------GRKTAVTLLLVYSIFLYLL 305
R + LLL++ +FLY +
Sbjct: 123 EGAVESTLSRSEGLILLLIFCVFLYYI 149
>pir||H82064 conserved hypothetical protein VC2522 [imported] - Vibrio cholerae
(group O1 strain N16961) >gi|9657106|gb|AAF95664.1|
(AE004322) conserved hypothetical protein [Vibrio
cholerae]
Length = 332
Score = 173 bits (434), Expect = 2e-42
Identities = 107/319 (33%), Positives = 188/319 (58%), Gaps = 14/319 (4%)
Query: 1 MEVAIVTAVFI-LGLILLIKGSDIFVNAATRIAETFGVSEFLIALVLASIATTLPEATVS 59
+ + I VF+ +GL +L+ G+D V + +A G+S +I + + ++ ++ PE VS
Sbjct: 11 INMLIEAVVFLFIGLAILVWGADKLVFGSAALARNIGISPLVIGMTILAMGSSAPEMMVS 70
Query: 60 AISSYKGNSGIALGNAVGSALANIALILGISAMITPLKVDEVANENSL-IMLGVTLYAWL 118
A ++ +G + A+GN +GS +ANIALILGI+A++ PL V L +M+GVTL A
Sbjct: 71 ATAALEGKTDTAVGNVLGSNIANIALILGITAIVKPLSVGSAVLRRELPMMIGVTLIAGA 130
Query: 119 LMINGEISRIEGLTLVLIYGAFLYYLYRKHVK--------LEEIEEESRGNVIKDIAILF 170
++ + + EG+ L+ ++ AF+ + + K L+E E E V A +
Sbjct: 131 ILWDNHLGFYEGILLIALFAAFILVMLQVSRKEKQNGDALLDEQESEIPVGVSNPKAAFW 190
Query: 171 LSGGMVIL--GAELVVDSAVKIARGAGIPEVVIGVTLVSIGTSLPELANSLTAALKGIHN 228
+ G+++L GA ++VD+AV IA+ G+ ++VIG+T++++GTSLPELA SL ALKG +
Sbjct: 191 VVVGLILLPIGAGMLVDNAVVIAKYFGMSDLVIGLTIIAVGTSLPELAASLAGALKGEDD 250
Query: 229 VSVGNIIGADIIDILMVIGIASIIRPIKVDPSIVKVTMPITVLVMAILT-VSLFRNNKVG 287
++VGNIIG+++ +IL V+G+ ++ P + P + + + V +L V+L + ++
Sbjct: 251 MAVGNIIGSNVFNILAVMGLPGLLNPSLLSPEAMSRDFWVMLGVSLLLVGVALGKKRQIT 310
Query: 288 RKTAVTLLLVYSIFL-YLL 305
R LL + ++ YLL
Sbjct: 311 RLEGALLLCSFIGYITYLL 329
Score = 93.6 bits (229), Expect = 3e-18
Identities = 44/146 (30%), Positives = 96/146 (65%), Gaps = 1/146 (0%)
Query: 162 VIKDIAILFLSGGMVILGAELVVDSAVKIARGAGIPEVVIGVTLVSIGTSLPELANSLTA 221
+I+ + LF+ +++ GA+ +V + +AR GI +VIG+T++++G+S PE+ S TA
Sbjct: 14 LIEAVVFLFIGLAILVWGADKLVFGSAALARNIGISPLVIGMTILAMGSSAPEMMVSATA 73
Query: 222 ALKGIHNVSVGNIIGADIIDILMVIGIASIIRPIKVDPSIVKVTMPITVLVMAILTVSLF 281
AL+G + +VGN++G++I +I +++GI +I++P+ V ++++ +P+ + V I L+
Sbjct: 74 ALEGKTDTAVGNVLGSNIANIALILGITAIVKPLSVGSAVLRRELPMMIGVTLIAGAILW 133
Query: 282 RNNKVGRKTAVTLLLVYSIFLYLLAQ 307
+N +G + L+ +++ F+ ++ Q
Sbjct: 134 -DNHLGFYEGILLIALFAAFILVMLQ 158
>pir||S74922 hypothetical protein slr0681 - Synechocystis sp. (strain PCC 6803)
>gi|1652037|dbj|BAA16962.1| (D90902) hypothetical
protein [Synechocystis sp.]
Length = 433
Score = 170 bits (426), Expect = 2e-41
Identities = 112/308 (36%), Positives = 187/308 (60%), Gaps = 21/308 (6%)
Query: 11 ILGLILLIKGSDIFVNAATRIAETFGVSEFLIALVLASIATTLPEATVSAISSYKGNSGI 70
ILGL +L+ G++I V A+RIA G+S +I L + + T++PE VS ++ G + I
Sbjct: 76 ILGLGILVAGAEILVKGASRIALMAGLSPLIIGLTIVAYGTSMPEMVVSLQAAIAGQADI 135
Query: 71 ALGNAVGSALANIALILGISAMITPLKV-DEVANENSLIMLGVTLYAWLLMINGEISRIE 129
++GN VGS + N+ LILG+ ++ITPL V ++ + I++GV+ + +G+ISR++
Sbjct: 136 SIGNVVGSNIFNVLLILGVCSIITPLIVAQQLIRLDIPILIGVSGLLLMFGWDGQISRVD 195
Query: 130 GLTLVLIYGAFLY--YLYRKHVK------LEEIEEESRGNVIKD-----IAILFLSGG-- 174
G+ +L GA LY +L R+ K EE +E V K I I ++ GG
Sbjct: 196 GV--ILASGAILYTTFLIRQSKKENNPDVTEEYLKEFGEPVPKTGKQIFIQIAYVVGGVA 253
Query: 175 MVILGAELVVDSAVKIARGAGIPEVVIGVTLVSIGTSLPELANSLTAALKGIHNVSVGNI 234
+++LG+ L+V S+V IA+ GI E+VIG+TL++ GTSLPELA S+ A+ +G +++VGN+
Sbjct: 254 LLVLGSSLLVKSSVAIAKSLGISELVIGLTLIAAGTSLPELATSVVASYRGERDIAVGNV 313
Query: 235 IGADIIDILMVIGIASIIRP--IKVDPSIVKVTMPITVLVMAILTVSLFRNNKVGRKTAV 292
+G++I +IL V+G A+I P I+V S +P+ + +A++ + +F ++ +
Sbjct: 314 VGSNIFNILAVLGFAAIFSPNGIQVSNSAFNFDIPV-MFAVALVCLPVFITGRLIDRWEG 372
Query: 293 TLLLVYSI 300
L L Y I
Sbjct: 373 FLFLFYYI 380
Score = 96.7 bits (237), Expect = 3e-19
Identities = 49/140 (35%), Positives = 93/140 (66%), Gaps = 4/140 (2%)
Query: 166 IAILFLSGGMVILGAELVVDSAVKIARGAGIPEVVIGVTLVSIGTSLPELANSLTAALKG 225
I L L G+++ GAE++V A +IA AG+ ++IG+T+V+ GTS+PE+ SL AA+ G
Sbjct: 72 IPFLILGLGILVAGAEILVKGASRIALMAGLSPLIIGLTIVAYGTSMPEMVVSLQAAIAG 131
Query: 226 IHNVSVGNIIGADIIDILMVIGIASIIRPIKVDPSIVKVTMPITVLVMAILTVSLFRNNK 285
++S+GN++G++I ++L+++G+ SII P+ V ++++ +PI + V +L + + + +
Sbjct: 132 QADISIGNVVGSNIFNVLLILGVCSIITPLIVAQQLIRLDIPILIGVSGLLLMFGW-DGQ 190
Query: 286 VGRKTAVTL---LLVYSIFL 302
+ R V L ++Y+ FL
Sbjct: 191 ISRVDGVILASGAILYTTFL 210
Score = 88.9 bits (217), Expect = 7e-17
Identities = 53/147 (36%), Positives = 83/147 (56%), Gaps = 4/147 (2%)
Query: 2 EVAIVTAVFILGLILLIKGSDIFVNAATRIAETFGVSEFLIALVLASIATTLPEATVSAI 61
++ I A + G+ LL+ GS + V ++ IA++ G+SE +I L L + T+LPE S +
Sbjct: 240 QIFIQIAYVVGGVALLVLGSSLLVKSSVAIAKSLGISELVIGLTLIAAGTSLPELATSVV 299
Query: 62 SSYKGNSGIALGNAVGSALANIALILGISAMITP--LKVDEVA-NENSLIMLGVTLYAWL 118
+SY+G IA+GN VGS + NI +LG +A+ +P ++V A N + +M V L
Sbjct: 300 ASYRGERDIAVGNVVGSNIFNILAVLGFAAIFSPNGIQVSNSAFNFDIPVMFAVALVCLP 359
Query: 119 LMINGE-ISRIEGLTLVLIYGAFLYYL 144
+ I G I R EG + Y A+ YL
Sbjct: 360 VFITGRLIDRWEGFLFLFYYIAYTAYL 386
>pir||E70306 conserved hypothetical protein aq_066 - Aquifex aeolicus
>gi|2982830|gb|AAC06453.1| (AE000672) hypothetical
protein [Aquifex aeolicus]
Length = 322
Score = 169 bits (423), Expect = 5e-41
Identities = 110/309 (35%), Positives = 176/309 (56%), Gaps = 17/309 (5%)
Query: 12 LGLILLIKGSDIFVNAATRIAETFGVSEFLIALVLASIATTLPEATVSAISSYKGNSGIA 71
LG LL+KG+D+ + A +A FG+ EF+I L L + T+LPE TV+ ++ K SGI+
Sbjct: 10 LGFFLLVKGADMLIEGAGGLARRFGIPEFVIGLTLVAFGTSLPEFTVNVSAALKDASGIS 69
Query: 72 LGNAVGSALANIALILGISAMITPLKVDE--VANE---NSLIMLGVTLYAWLLMIN---- 122
LGN +GS +ANI LILG++++I PL V V E N + L + + A +++N
Sbjct: 70 LGNVIGSNIANILLILGVASLIKPLTVHATFVKKEIPVNFFLTLTLIVMANDVILNHAPV 129
Query: 123 GEISRIEGLTLVLIYGAFLYYL--YRKHVKLEEIEEESRGNVIKDIAILFLSGGMVILGA 180
ISR +GL L++ + ++Y+L Y + + E E + + K L + LGA
Sbjct: 130 SLISRGDGLVLIITFLGYMYFLVAYLERDSILEGEMKESISPFKGFIYFILGLTGLSLGA 189
Query: 181 ELVVDSAVKIARGAGIPEVVIGVTLVSIGTSLPELANSLTAALKGIHNVSVGNIIGADII 240
+ VD AV +A+ G+ E VIG+ +V+IGTSLPEL S +A KG ++++GN+ G++I
Sbjct: 190 DWTVDGAVGLAKALGVSEAVIGLFVVAIGTSLPELFASAVSAYKGNPDIALGNVAGSNIF 249
Query: 241 DILMVIGIASIIRPIKVDPSIVKVTMPITVLVMAILTVSLF---RNNKVGRKTAVTLLLV 297
+ +V+G +S+IR I V P V + + + +L +S R + R LL
Sbjct: 250 NATLVLGTSSVIRDIPV-PERANVDLGVLFIATLLLLISSIWGKRKYTLDRMEGGIFLLA 308
Query: 298 YSIFLYLLA 306
Y F+Y++A
Sbjct: 309 Y--FIYVIA 315
Score = 103 bits (254), Expect = 3e-21
Identities = 51/151 (33%), Positives = 97/151 (63%), Gaps = 7/151 (4%)
Query: 162 VIKDIAILFLSGGMVILGAELVVDSAVKIARGAGIPEVVIGVTLVSIGTSLPELANSLTA 221
++ D+ +L L +++ GA+++++ A +AR GIPE VIG+TLV+ GTSLPE +++A
Sbjct: 1 MLTDLGLLTLGFFLLVKGADMLIEGAGGLARRFGIPEFVIGLTLVAFGTSLPEFTVNVSA 60
Query: 222 ALKGIHNVSVGNIIGADIIDILMVIGIASIIRPIKVDPSIVKVTMPIT---VLVMAILTV 278
ALK +S+GN+IG++I +IL+++G+AS+I+P+ V + VK +P+ L + ++
Sbjct: 61 ALKDASGISLGNVIGSNIANILLILGVASLIKPLTVHATFVKKEIPVNFFLTLTLIVMAN 120
Query: 279 SLFRNNK----VGRKTAVTLLLVYSIFLYLL 305
+ N+ + R + L++ + ++Y L
Sbjct: 121 DVILNHAPVSLISRGDGLVLIITFLGYMYFL 151
Score = 92.1 bits (225), Expect = 8e-18
Identities = 60/143 (41%), Positives = 82/143 (56%), Gaps = 14/143 (9%)
Query: 10 FILGLILLIKGSDIFVNAATRIAETFGVSEFLIALVLASIATTLPEATVSAISSYKGNSG 69
FILGL L G+D V+ A +A+ GVSE +I L + +I T+LPE SA+S+YKGN
Sbjct: 178 FILGLTGLSLGADWTVDGAVGLAKALGVSEAVIGLFVVAIGTSLPELFASAVSAYKGNPD 237
Query: 70 IALGNAVGSALANIALILGISAMITPLKVDEVANENSLIMLGVTLYAWLLMINGEI---- 125
IALGN GS + N L+LG S++I + V E AN + LGV A LL++ I
Sbjct: 238 IALGNVAGSNIFNATLVLGTSSVIRDIPVPERAN----VDLGVLFIATLLLLISSIWGKR 293
Query: 126 ----SRIEGLTLVLIYGAFLYYL 144
R+EG +L Y F+Y +
Sbjct: 294 KYTLDRMEGGIFLLAY--FIYVI 314
>pir||B72342 conserved hypothetical protein - Thermotoga maritima (strain MSB8)
>gi|4981249|gb|AAD35806.1|AE001743_8 (AE001743)
conserved hypothetical protein [Thermotoga maritima]
Length = 309
Score = 168 bits (422), Expect = 6e-41
Identities = 95/300 (31%), Positives = 175/300 (57%), Gaps = 8/300 (2%)
Query: 12 LGLILLIKGSDIFVNAATRIAETFGVSEFLIALVLASIATTLPEATVSAISSYKGNSGIA 71
LG+ +L+ G++ V A+ +A T G+S+ ++ L + + T+LPE S +S+ KG S IA
Sbjct: 8 LGIAILVIGANWLVTGASSLALTLGISKLIVGLSVVAFGTSLPELVSSLVSASKGYSSIA 67
Query: 72 LGNAVGSALANIALILGISAMI--TPLKVDEVANENSLIMLGVTLYAWLLMINGEISRIE 129
+ N VGS +AN+ L LG++A++ P+K V +E ++L + L + N +S +
Sbjct: 68 ISNVVGSNIANVGLCLGLAAVLRAVPVKRSTVRSEIPFMILATISFISLFLKNYYLSWHD 127
Query: 130 GLTLVLIYGAFLYYLYR--KHVKLEEIEEESRGNVIKDIAILFLSGGMVIL--GAELVVD 185
G+ + F+YYL K V EE+EE + +++L + GG++ L G +L ++
Sbjct: 128 GVVFLSFMVIFMYYLITSAKEVVEEELEEIKPQKSVA-VSLLMIVGGILALWFGGDLAIE 186
Query: 186 SAVKIARGAGIPEVVIGVTLVSIGTSLPELANSLTAALKGIHNVSVGNIIGADIIDILMV 245
+AVKIA G+ + IG+T++++GTSLPEL S+ + K ++ VGNI+G+++ +IL++
Sbjct: 187 NAVKIAETFGLSQAFIGLTVIAVGTSLPELVVSIVSTAKKESDILVGNIVGSNVFNILLI 246
Query: 246 IGIASIIRPIKVDPSIVKVTMPITVLVMAILTVSLFRNNKVGRKTAVTLLLVYSIFLYLL 305
+G++S + VD + V + + A+L V ++ R L++YS+++Y +
Sbjct: 247 LGVSSFFGRLTVDVN-YSVDLWFLFITSALLLVFAVSRRRISRFEGAVFLIIYSVYVYFV 305
Score = 89.7 bits (219), Expect = 4e-17
Identities = 54/144 (37%), Positives = 82/144 (56%), Gaps = 3/144 (2%)
Query: 3 VAIVTAVFILGLILLIKGSDIFVNAATRIAETFGVSEFLIALVLASIATTLPEATVSAIS 62
VA+ + + G++ L G D+ + A +IAETFG+S+ I L + ++ T+LPE VS +S
Sbjct: 163 VAVSLLMIVGGILALWFGGDLAIENAVKIAETFGLSQAFIGLTVIAVGTSLPELVVSIVS 222
Query: 63 SYKGNSGIALGNAVGSALANIALILGISAMITPLKVDEVANENSLIMLGVT--LYAWLLM 120
+ K S I +GN VGS + NI LILG+S+ L VD V L L +T L +
Sbjct: 223 TAKKESDILVGNIVGSNVFNILLILGVSSFFGRLTVD-VNYSVDLWFLFITSALLLVFAV 281
Query: 121 INGEISRIEGLTLVLIYGAFLYYL 144
ISR EG ++IY ++Y++
Sbjct: 282 SRRRISRFEGAVFLIIYSVYVYFV 305
>sp|P45394|YRBG_ECOLI HYPOTHETICAL 34.7 KD PROTEIN IN MURA-RPON INTERGENIC REGION (O325)
>gi|7465977|pir||F65110 hypothetical 34.7 kD protein in
murZ-rpoN intergenic region - Escherichia coli (strain
K-12) >gi|606134|gb|AAA57997.1| (U18997) ORF_o325
[Escherichia coli] >gi|1789587|gb|AAC76228.1| (AE000399)
orf, hypothetical protein [Escherichia coli K12]
Length = 325
Score = 165 bits (414), Expect = 5e-40
Identities = 100/314 (31%), Positives = 183/314 (57%), Gaps = 13/314 (4%)
Query: 5 IVTAVFILGLILLIKGSDIFVNAATRIAETFGVSEFLIALVLASIATTLPEATVSAISSY 64
+ TA+ I+GL+L++ +D V AA+ + TFG+ +I + + SI T+LPE VS +S
Sbjct: 3 LATALLIVGLLLVVYSADRLVFAASILCRTFGIPPLIIGMTVVSIGTSLPEVIVSLAASL 62
Query: 65 KGNSGIALGNAVGSALANIALILGISAMITPLKV-DEVANENSLIMLGVTLYAWLLMING 123
+A+G A+GS + NI LILG++A++ P V +V +ML V++ A ++ +G
Sbjct: 63 HEQRDLAVGTALGSNIINILLILGLAALVRPFTVHSDVLRRELPLMLLVSVVAGSVLYDG 122
Query: 124 EISRIEGLTLVLIYGAFLYYLYRKHVKLEE-----IEEESRGNVIKD----IAILFLSGG 174
++SR +G+ L+ + +L ++ + + E + E + +D +A L+L
Sbjct: 123 QLSRSDGIFLLFLAVLWLLFIVKLARQAERQGTDSLTREQLAELPRDGGLPVAFLWLGIA 182
Query: 175 MVIL--GAELVVDSAVKIARGAGIPEVVIGVTLVSIGTSLPELANSLTAALKGIHNVSVG 232
++I+ +VVD+A +A I E+ +G+T ++IGTSLPELA ++ KG ++++VG
Sbjct: 183 LIIMPVATRMVVDNATVLANYFAISELTMGLTAIAIGTSLPELATAIAGVRKGENDIAVG 242
Query: 233 NIIGADIIDILMVIGIASIIRPIKVDPSIVKVTMPITVLVMAILTVSLFRNN-KVGRKTA 291
NIIGA+I +I++V+G+ ++I P ++DP + +LV I + +R + + GR
Sbjct: 243 NIIGANIFNIVIVLGLPALITPGEIDPLAYSRDYSVMLLVSIIFALLCWRRSPQPGRGVG 302
Query: 292 VTLLLVYSIFLYLL 305
V L + ++L +L
Sbjct: 303 VLLTGGFIVWLAML 316
Score = 90.5 bits (221), Expect = 2e-17
Identities = 46/141 (32%), Positives = 93/141 (65%), Gaps = 1/141 (0%)
Query: 167 AILFLSGGMVILGAELVVDSAVKIARGAGIPEVVIGVTLVSIGTSLPELANSLTAALKGI 226
A+L + +V+ A+ +V +A + R GIP ++IG+T+VSIGTSLPE+ SL A+L
Sbjct: 6 ALLIVGLLLVVYSADRLVFAASILCRTFGIPPLIIGMTVVSIGTSLPEVIVSLAASLHEQ 65
Query: 227 HNVSVGNIIGADIIDILMVIGIASIIRPIKVDPSIVKVTMPITVLVMAILTVSLFRNNKV 286
+++VG +G++II+IL+++G+A+++RP V +++ +P+ +LV +++ S+ + ++
Sbjct: 66 RDLAVGTALGSNIINILLILGLAALVRPFTVHSDVLRRELPLMLLV-SVVAGSVLYDGQL 124
Query: 287 GRKTAVTLLLVYSIFLYLLAQ 307
R + LL + ++L + +
Sbjct: 125 SRSDGIFLLFLAVLWLLFIVK 145
>pir||H69020 probable Na+/Ca2+,K+-exchanging protein - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2622261|gb|AAB85644.1| (AE000885) Na+/Ca+ exchanging
protein related [Methanobacterium thermoautotrophicum]
Length = 330
Score = 156 bits (390), Expect = 3e-37
Identities = 90/309 (29%), Positives = 177/309 (57%), Gaps = 8/309 (2%)
Query: 3 VAIVTAVFILGLILLIKGSDIFVNAATRIAETFGVSEFLIALVLASIATTLPEATVSAIS 62
V I+ + LIL+IK +D+FV+ + + G+SE ++ + ++I T+LPE + I+
Sbjct: 17 VLILIVGLVASLILVIKSADLFVDNLVDLGSSLGISEVILGVTASAIGTSLPEFGSALIA 76
Query: 63 SYKGNSGIALGNAVGSALANIALILGISAMITPL---KVDEVANENSLIMLGVTLYAWLL 119
S G++ I +G +GS + NIA ILGIS+++ + D + + S ++ L
Sbjct: 77 SLSGSTDIGVGCVIGSNIWNIAGILGISSVVAGIIETNADGLKRDFSATLV-TGLILLFF 135
Query: 120 MINGEISRIEGLTLVLIYGAFLYYLYRKHVKLEEI---EEESRGNVIKDIAILFLSGGMV 176
M G I +I L +VL Y +L+ L + + + E +K +A+ + +
Sbjct: 136 MFFGNIGKIAALVMVLTYAVYLWRLIKAQKTYSDENSGKNEREPLDLKKLALTVVGFAGL 195
Query: 177 ILGAELVVDSAVKIARGAGIPEVVIGVTLVSIGTSLPELANSLTAALKGIHNVSVGNIIG 236
++G ++V + V++A AGIP +++G+ ++IGTS+PEL +L++A+KG+H +S+G ++G
Sbjct: 196 VIGCRILVYTGVELADIAGIPAMIMGLFTLAIGTSIPELVVTLSSAVKGLHELSIGTVLG 255
Query: 237 ADIIDILMVIGIASIIRPIKVDPSIVKVTMPITVLVMAILTVSLFRNN-KVGRKTAVTLL 295
++ +IL+ IG+ ++I P+ V+ + P+ +LV +L + + + + K+ R + LL
Sbjct: 256 SNTFNILVGIGVPALIAPVPVERLSLTFDAPVMILVTVLLVLLIRQGDMKLKRTGGIVLL 315
Query: 296 LVYSIFLYL 304
VY ++ +
Sbjct: 316 AVYISYVIM 324
Score = 85.0 bits (207), Expect = 1e-15
Identities = 52/157 (33%), Positives = 95/157 (60%), Gaps = 6/157 (3%)
Query: 158 SRGNVIKDIAILFL----SGGMVILGAELVVDSAVKIARGAGIPEVVIGVTLVSIGTSLP 213
S N+++ + IL + S +VI A+L VD+ V + GI EV++GVT +IGTSLP
Sbjct: 9 SGDNLLERVLILIVGLVASLILVIKSADLFVDNLVDLGSSLGISEVILGVTASAIGTSLP 68
Query: 214 ELANSLTAALKGIHNVSVGNIIGADIIDILMVIGIASIIRPI-KVDPSIVKVTMPITVLV 272
E ++L A+L G ++ VG +IG++I +I ++GI+S++ I + + +K T++
Sbjct: 69 EFGSALIASLSGSTDIGVGCVIGSNIWNIAGILGISSVVAGIIETNADGLKRDFSATLVT 128
Query: 273 MAILTVSLFRNNKVGRKTAVTLLLVYSIFLYLLAQGK 309
IL +F N +G+ A+ ++L Y+++L+ L + +
Sbjct: 129 GLILLFFMFFGN-IGKIAALVMVLTYAVYLWRLIKAQ 164
>gb|AAG18939.1| (AE004995) cation antiporter; Caa [Halobacterium sp. NRC-1]
Length = 318
Score = 153 bits (383), Expect = 2e-36
Identities = 95/311 (30%), Positives = 173/311 (55%), Gaps = 19/311 (6%)
Query: 9 VFILGLILLIKGSDIFVNAATRIAETFGVSEFLIALVLASIATTLPEATVSAISSYKGNS 68
+ + G++LL G+++ V+AA+ +A + G+ + + + + ATT PE VS +
Sbjct: 11 ILVAGILLLYVGAELLVSAASALALSHGIKAATVGVTVVAFATTAPELFVSTVGGITAGD 70
Query: 69 GIALGNAVGSALANIALILGISAMITPLKVDE-VANENSLIMLGVTLYAWLLMINGEISR 127
IALGN VGS +ANI L+LG +A++ P+ VD+ + + ML L L ++G +
Sbjct: 71 SIALGNIVGSNIANIGLVLGTAALLRPMDVDKTLLYHHGPFMLAAALALVGLSLDGTLGA 130
Query: 128 IEGLTLVLIYGAFLYYLYRKHVKLEEIEEESRGNV-IKDIAILFLSGGMVILGAELVV-- 184
++G+ L+ + F Y+YR H + ++ + +V + D A +V++GA L++
Sbjct: 131 LDGVALLALLAVFTAYIYR-HAQQDDDDVSLPDDVDMDDDATATARDYVVLVGAILLLLG 189
Query: 185 DSAVKIARGAGI------PEVVIGVTLVSIGTSLPELANSLTAALKGIHNVSVGNIIGAD 238
S I G G+ ++ IG+T+++ GTS+PELA S+ +AL+ + S+GN++G++
Sbjct: 190 GSRALITGGRGVLMEFGFSDLFIGLTVIAFGTSVPELATSVVSALRDEADFSIGNVVGSN 249
Query: 239 IIDILMVIGIASIIRPIKVDPSIVKVTMPI----TVLVMAILTVSLFRNNKVGRKTAVTL 294
I ++L VIGI +I+ PI V + +P+ TVL + ++ V +++ R L
Sbjct: 250 IYNVLAVIGIVAILVPITVTKGTLAFELPVMLGFTVLALGMMAV----GDRITRVEGAVL 305
Query: 295 LLVYSIFLYLL 305
+ Y F+Y L
Sbjct: 306 IGSYGGFVYFL 316
>pir||E69009 cation antiporter - Methanobacterium thermoautotrophicum (strain
Delta H) >gi|2622172|gb|AAB85562.1| (AE000878) cation
antiporter [Methanobacterium thermoautotrophicum]
Length = 322
Score = 142 bits (354), Expect = 6e-33
Identities = 89/303 (29%), Positives = 168/303 (55%), Gaps = 7/303 (2%)
Query: 1 MEVAIVTAVFILGLILLIKGSDIFVNAATRIAETFGVSEFLIALVLASIATTLPEATVSA 60
M V I+ +F + LI +IK +DIFV+ I G+S+ ++ + +A+ T+LPE +
Sbjct: 10 MSVIILLFLFTVSLIGVIKSADIFVDRIVDIGRALGISQIILGVTVAAAGTSLPEFGSAL 69
Query: 61 ISSYKGNSGIALGNAVGSALANIALILGISAMIT---PLKVDEVANENSLIMLGVTLYAW 117
IS GN + +G +GS + NIA I+GISA+++ DE+ + +L + + +
Sbjct: 70 ISVLTGNPDLGVGVVIGSNIWNIAGIIGISAILSCAVTTNRDEIRRDGLFGLLSILILTF 129
Query: 118 LLMINGEISRIEGLTLVLIYGAFLYYLYRKHVKLEEIEEESRGNVIKDIAILFLSG--GM 175
+++ G + + G+ L+ +YG +L+ L +K G V I + G G+
Sbjct: 130 FMLM-GPVGPLTGVVLLALYGVYLWVLIKKQRGYYTSHLMDHGEVDAKTIISAILGFTGL 188
Query: 176 VILGAELVVDSAVKIARGAGIPEVVIGVTLVSIGTSLPELANSLTAALKGIHNVSVGNII 235
V+ ++V SAV IA +PE++IG+ ++IGTSL EL ++ +A+K + ++S+G ++
Sbjct: 189 VVF-CRILVYSAVGIAEIMNVPEMIIGLFALAIGTSLAELVVAVNSAMKRMCSLSLGTVL 247
Query: 236 GADIIDILMVIGIASIIRPIKVDPSIVKVTMPITVLVMAILTVSLFRNNKVGRKTAVTLL 295
G++I +IL+ IG+ S+ I V+P + + P+ + V + ++ + ++ R V L+
Sbjct: 248 GSNIFNILIGIGVPSLFVRIPVEPLSLILDAPVLMGVTVAVMYFMWTDMELRRVEGVALV 307
Query: 296 LVY 298
Y
Sbjct: 308 AFY 310
>pir||A71250 conserved hypothetical integral membrane protein TP1034 - syphilis
spirochete >gi|3323364|gb|AAC26588.1| (AE001271)
conserved hypothetical integral membrane protein
[Treponema pallidum]
Length = 341
Score = 132 bits (329), Expect = 5e-30
Identities = 85/314 (27%), Positives = 159/314 (50%), Gaps = 19/314 (6%)
Query: 9 VFILGLILLIKGSDIFVNAATRIAETFGVSEFLIALVLASIATTLPEATVSAISSYKGNS 68
V + L L + +D V +A+ ++ +G+SE L+ L S+ TT PEA VS ++ GN+
Sbjct: 20 VLLCALYFLARSADCLVESASALSRRWGISEALLGATLVSLGTTTPEAAVSVYAALCGNA 79
Query: 69 GIALGNAVGSALANIALILGISAMIT----PLKVDEVANENSLIMLGVTLYAWLLM--IN 122
+ALGNA+GS + + ILG+ A++ L + + + V W+ +
Sbjct: 80 DLALGNAIGSIVVDTGFILGLGALLARPGLALDTHLMRRHARVQLFVVCALGWVTLPRFG 139
Query: 123 GEISRIEGLTLVLIYGAFLYYLYR----------KHVKLEEIEEESRGNVIKDIAILFLS 172
+ + G + + +L+ R + L + ++R +V + + L
Sbjct: 140 ARVHQYVGWLFLSLLALYLWVSLRWSALPHAPDTRTAALPADKTDTR-SVCRLLLQLGGG 198
Query: 173 GGMVILGAELVVDSAVKIARGAGIPEVVIGVTLVSIGTSLPELANSLTAALKGIHNVSVG 232
G ++LG+ +++ + +A AG+P +I T+++ GTS+PEL +++TA +G ++VG
Sbjct: 199 IGFLVLGSRVLIPTVEIMALRAGVPAGIIAATIIAFGTSVPELVSAITAVRRGHGALAVG 258
Query: 233 NIIGADIIDILMVIGIASIIRP--IKVDPSIVKVTMPITVLVMAILTVSLFRNNKVGRKT 290
NI+GADI+++L V+G A+ + P + V + +P +LV+ I + R
Sbjct: 259 NIVGADILNVLFVVGAAASLTPHGLPVPKIFSLLHLPAMLLVVGIFHACALGRRTLTRPA 318
Query: 291 AVTLLLVYSIFLYL 304
V L VY +F+ L
Sbjct: 319 GVLLCAVYGLFVLL 332
>pir||D70120 probable Na+/Ca2+-exchanging protein - Lyme disease spirochete
>gi|2688049|gb|AAC66548.1| (AE001127) Na+/Ca+ exchange
protein, putative [Borrelia burgdorferi]
Length = 337
Score = 120 bits (297), Expect = 3e-26
Identities = 84/313 (26%), Positives = 159/313 (49%), Gaps = 23/313 (7%)
Query: 13 GLILLIKGSDIFVNAATRIAETFGVSEFLIALVLASIATTLPEATVSAISSYKGNSGIAL 72
G+ LL G ++ + ++ IA V LI + + S +T+ PE S ++++KG + I +
Sbjct: 22 GIFLLYLGGNLLLKSSVGIATYLKVPTLLIGVTIVSFSTSAPELFTSLVAAFKGKNEIVV 81
Query: 73 GNAVGSALANIALILGISAMITPLKVDEVANENSLIMLGVTLYAWLLM---------ING 123
N +GS + N+ L L ++ +K D + S + L + ++ LL+
Sbjct: 82 SNVIGSNIINMLLALPLAGFFLKIKADFKRLKLSFMFLFLLMFLLLLLSFDFRSYSFFVT 141
Query: 124 EISRIEGLTLVLIYGAFLYYLY---RKHVKLEEIEEESRGNVIKDIAILF-------LSG 173
+R ++++++ ++L Y +++ LE +E N+ + +F +S
Sbjct: 142 PYNRFSSFSILILFLSYLLLFYKEEKEYASLENSFQEGASNLNQSFNFIFFNLLSFAISM 201
Query: 174 GMVILGAELVVDSAVKIARGA-GIPEVVIGVTLVSIGTSLPELANSLTAALKGIHNVSVG 232
+ LG++L+VD A+ IA + E +IG+ LV+ GTS+PEL SL A ++ +++ G
Sbjct: 202 YFLYLGSKLLVDGALYIANNVFNVSEKLIGIILVAFGTSVPELVVSLFAIIRKESDIAFG 261
Query: 233 NIIGADIIDILMVIGIASIIRPIKVDPSIVKVTMPITVLVMAILTVSLFRNNKVGRKTAV 292
NIIG++I +I ++ +S RPI + I + I V + +L + + GR ++
Sbjct: 262 NIIGSNIFNIGFILASSSFFRPILLQ-DIYILDFSIMVFITLVLFLVVKFKGVFGRGISL 320
Query: 293 TLLLVYSIFLYLL 305
LL+Y FLY L
Sbjct: 321 IFLLLY--FLYNL 331
Score = 71.4 bits (172), Expect = 1e-11
Identities = 46/137 (33%), Positives = 74/137 (53%), Gaps = 4/137 (2%)
Query: 10 FILGLILLIKGSDIFVNAATRIAET-FGVSEFLIALVLASIATTLPEATVSAISSYKGNS 68
F + + L GS + V+ A IA F VSE LI ++L + T++PE VS + + S
Sbjct: 197 FAISMYFLYLGSKLLVDGALYIANNVFNVSEKLIGIILVAFGTSVPELVVSLFAIIRKES 256
Query: 69 GIALGNAVGSALANIALILGISAMITPLKVDEVANENSLIMLGVTLYAWLLM-INGEISR 127
IA GN +GS + NI IL S+ P+ + ++ + IM+ +TL +L++ G R
Sbjct: 257 DIAFGNIIGSNIFNIGFILASSSFFRPILLQDIYILDFSIMVFITLVLFLVVKFKGVFGR 316
Query: 128 IEGLTLVLIYGAFLYYL 144
G++L+ + FLY L
Sbjct: 317 --GISLIFLLLYFLYNL 331
>pir||T45258 hypothetical protein [imported] - Methanobacterium
thermoautotrophicum (fragment)
>gi|1296938|emb|CAA66197.1| (X97589) ORF318
[Methanobacterium thermoautotrophicum]
Length = 160
Score = 97.5 bits (239), Expect = 2e-19
Identities = 46/143 (32%), Positives = 95/143 (66%), Gaps = 1/143 (0%)
Query: 163 IKDIAILFLSGGMVILGAELVVDSAVKIARGAGIPEVVIGVTLVSIGTSLPELANSLTAA 222
+K +A+ + +++G ++V S V++A AGIP +++G+ ++IGTS+PEL +L++A
Sbjct: 12 LKKLALTVVGFTGLVIGCRILVYSGVELADIAGIPAMIMGLFTLAIGTSIPELVVTLSSA 71
Query: 223 LKGIHNVSVGNIIGADIIDILMVIGIASIIRPIKVDPSIVKVTMPITVLVMAILTVSLFR 282
+KG+H +S+G ++G++ +IL+ IG+ ++I P+ V+P ++ PI +LV +L + + +
Sbjct: 72 VKGLHELSIGTVLGSNTFNILVGIGVPALIAPVPVEPLSLRFDAPIMILVTVLLVLLIKQ 131
Query: 283 NN-KVGRKTAVTLLLVYSIFLYL 304
+ K+ R + LL VY ++ +
Sbjct: 132 GDMKLKRSGGIILLAVYISYVVM 154
>pir||S68978 Na+/Ca2+,K+-exchanging protein homolog - Methanobacterium
thermoautotrophicum (strain Marburg) (fragment)
Length = 158
Score = 94.0 bits (230), Expect = 2e-18
Identities = 55/151 (36%), Positives = 95/151 (62%), Gaps = 2/151 (1%)
Query: 160 GNVIKDIAILFLSGGMVILGAELVVDSAVKIARGAGIPEVVIGVTLVSIGTSLPELANSL 219
GNV+ IA L +S +VI A++ VD+ V + GI EV++GVT +IGTSLPE ++L
Sbjct: 3 GNVLILIAALVVSLILVIKSADIFVDNLVDLGSSLGISEVILGVTASAIGTSLPEFGSAL 62
Query: 220 TAALKGIHNVSVGNIIGADIIDILMVIGIASIIR-PIKVDPSIVKVTMPITVLVMAILTV 278
A+L G ++ VG +IG++I +I ++GI++++ I+ + +K T++ IL
Sbjct: 63 IASLSGSTDIGVGCVIGSNIWNIAGILGISALVAGVIETNADGLKRDFSATLMTGLILLF 122
Query: 279 SLFRNNKVGRKTAVTLLLVYSIFLYLLAQGK 309
+F N +GR AV ++L+YS++L+ L + +
Sbjct: 123 FMFFGN-IGRLAAVAMVLLYSVYLWRLIKAQ 152
Score = 84.7 bits (206), Expect = 1e-15
Identities = 49/148 (33%), Positives = 87/148 (58%), Gaps = 6/148 (4%)
Query: 3 VAIVTAVFILGLILLIKGSDIFVNAATRIAETFGVSEFLIALVLASIATTLPEATVSAIS 62
V I+ A ++ LIL+IK +DIFV+ + + G+SE ++ + ++I T+LPE + I+
Sbjct: 5 VLILIAALVVSLILVIKSADIFVDNLVDLGSSLGISEVILGVTASAIGTSLPEFGSALIA 64
Query: 63 SYKGNSGIALGNAVGSALANIALILGISAMITPL---KVDEVANE-NSLIMLGVTLYAWL 118
S G++ I +G +GS + NIA ILGISA++ + D + + ++ +M G+ L
Sbjct: 65 SLSGSTDIGVGCVIGSNIWNIAGILGISALVAGVIETNADGLKRDFSATLMTGLILL--F 122
Query: 119 LMINGEISRIEGLTLVLIYGAFLYYLYR 146
M G I R+ + +VL+Y +L+ L +
Sbjct: 123 FMFFGNIGRLAAVAMVLLYSVYLWRLIK 150
>gb|AAG20377.1| (AE005111) Na+/Ca2+-exchanging protein; Nce [Halobacterium sp.
NRC-1]
Length = 344
Score = 93.6 bits (229), Expect = 3e-18
Identities = 74/295 (25%), Positives = 143/295 (48%), Gaps = 22/295 (7%)
Query: 8 AVFILGLILLIKGSDIFVNAATRIAETFGVSEFLIALVLASIATTLPEATVSAISSYKGN 67
AV ++ +L+ GS AA +++ +G+ + ++ +I ++ PE +++ G+
Sbjct: 16 AVVVVATLLIWAGSSWLEAAAEQLSAHYGLPAVVQGSIVVAIGSSFPELLSVLVTALDGS 75
Query: 68 SGIALGNAVGSALANIALILGISAMITPLKVDE----VANENSLIMLGVT--LYAWLLMI 121
G+ +G VGSA+ NI ++ G++ + T +D V E ML V+ L + L +
Sbjct: 76 FGLGVGAIVGSAIFNILVVPGLAGITTTQPLDATRTVVYKEAQFYMLAVSTLLLTFALAV 135
Query: 122 -----------NGEISRIEGLTLVLIYGAFLYYLYRKHVKLEEIEEESRGNVIKDIAILF 170
+G ++R L +L+YG +L+ ++ + + + +V + A L
Sbjct: 136 IYAPIPGGDPLDGAVTRPLALVPLLLYGLYLFIQWQDVGDHDPTTDTTDVDVPRAWARLA 195
Query: 171 LSGGMVILGAELVVDSAVKIARGAGIPEVVIGVTLVSIGTSLPELANSLTAALKGIHNVS 230
+ + EL+V + +A IP + GVT+++ TSLP+ S+ AA G S
Sbjct: 196 AGLAAISVAVELLVGAVTGLAATFDIPSFLAGVTILAAATSLPDALVSVRAARSGHGVTS 255
Query: 231 VGNIIGADIIDILMVIGIASII---RPIK--VDPSIVKVTMPITVLVMAILTVSL 280
+GN++G++ D+L+ I I +I P+ V ++ V TVL+ +L L
Sbjct: 256 LGNVLGSNTFDLLVAIPIGVLIAGRAPVSFAVAAPLMGVLTLATVLLFTVLRTGL 310
>gb|AAK41422.1| Na(+)/Ca(2+) exchanging protein related [Sulfolobus solfataricus]
Length = 307
Score = 79.2 bits (192), Expect = 6e-14
Identities = 62/303 (20%), Positives = 145/303 (47%), Gaps = 15/303 (4%)
Query: 10 FILGLILLIKGSDIFVNAATRIAETFGVSEFLIALVLASIATTLPEATVSAISSYKGNSG 69
FI I + +++ A + + G + + ++ T LPE ++S +G+
Sbjct: 8 FIGIFIAIFVSAELLAKGADELEDFLG--QGITGGIILGFLTALPETIFVIVASLEGSFD 65
Query: 70 IALGNAVGSALANIALILGISAMI------TPLKVDEVANENSLIMLGVTLYAWLLMING 123
+ALG+A+G + L +G+ + T L++ + ++ ++ T+ L++I G
Sbjct: 66 VALGSAIGGNVLLFTLGIGLVGVFYAFKWRTALQISSEYSVENVFLVLTTIGMLLVLIYG 125
Query: 124 EISRIEGLTLVLIYGAFLYYLYRKHVKLEEIEEESRGNVIKDIAILFLSGGMVILGAELV 183
+++ I GL L+LIY +Y +YR E E +GN++K + + G ++++ +
Sbjct: 126 KLNIISGLLLILIY--VIYVVYRVAKFRREGMEREKGNLMKPVGFIIAGGVLLVVFSHYF 183
Query: 184 VDSAVKIARGAGIPEVVIGVTLVSIGTSLPELANSLTAAL--KGIHNVSVGNIIGADIID 241
V+ +IA +P + + + + I L E ++ L K ++S+ + +G+ I +
Sbjct: 184 VEYINEIAIMFNVPAIWLSLVIAPIAGELEEKISAFRLVLMSKDGGSLSILSFVGSKIEN 243
Query: 242 ILMVIGIASIIRPIKVDPSIVKVTMPITVLVMAILTVSLFRNNKVGRKTAVTLLLVYSIF 301
+++GI I ++ ++ + + L+ ++ + + + ++ +V L+ VY I
Sbjct: 244 ATVLLGIIGIFTDYELQQALPEYA---SSLIANMIALYVLFDKRLKTFESVILIGVYVII 300
Query: 302 LYL 304
+ L
Sbjct: 301 VIL 303
>gb|AAK43291.1| Conserved hypothetical protein [Sulfolobus solfataricus]
Length = 312
Score = 78.0 bits (189), Expect = 1e-13
Identities = 62/307 (20%), Positives = 146/307 (47%), Gaps = 21/307 (6%)
Query: 11 ILGLILLIKGSDIFVNAATRIAETFGVSEFLIALVLASIATTLPEATVSAISSYKGNSGI 70
I+ LIL+ + + + +FG + ++ LPE + + G I
Sbjct: 10 IVLLILVAFSATLMAKGTRELERSFGKG--IAGGLILGFINALPETIIVIQAVLNGFYDI 67
Query: 71 ALGNAVGSALANIALILGISAMITPLKV--------DEVANENSLIMLGVTLYAWLLMIN 122
ALG+A+G + + L +G+ ++ LK ++ E S +L V + + ++
Sbjct: 68 ALGSALGGNILLLTLGIGLISIFYYLKYKSNIITLDSDINIEYSSFLLAVIILG-IAIVY 126
Query: 123 GEISRIEGLTLVLIYGAFLYYLYRKHVKLEEI--EEESRGNVIKDIAILFLSGGMVILGA 180
G+++ GL L+ ++YY+YR++ I E+++GN IK +A + + G +I +
Sbjct: 127 GKLNYYIGLFLL---SPYIYYIYRRYKNYRGILKNEKNKGNAIKGLAYVMIGGLPLIFIS 183
Query: 181 ELVVDSAVKIARGAGIPEVVIGVTLVSIGTSLPE--LANSLTAALKGIHNVSVGNIIGAD 238
+ ++ + IA + +++ + + I L E A L + ++ N IG+
Sbjct: 184 KYLISTISSIASVFNVQPLILAILITPIAAELEENLTAIKLISDSPSSATTALMNFIGSK 243
Query: 239 IIDILMVIGIASIIRPIKVDPSIVKVTMPITVLVMAILTVSLFRNNKVGRKTAVTLLLVY 298
+ ++ +++ I I + + + PS++ + + +L ++L + + ++ + K ++L +Y
Sbjct: 244 LENMTLLLSIIGISQTVSLRPSLLYL---LLILATSLLALGIIKDRNIKVKEGLSLFGIY 300
Query: 299 SIFLYLL 305
+I + +L
Sbjct: 301 AILIAIL 307
>emb|CAC12320.1| (AL445066) conserved hypothetical membrane protein [Thermoplasma
acidophilum]
Length = 291
Score = 73.7 bits (178), Expect = 2e-12
Identities = 68/280 (24%), Positives = 122/280 (43%), Gaps = 9/280 (3%)
Query: 10 FILGLILLIKGSDIFVNAATRIAETFGVSEFLIALVLASIATTLPEATVSAISSYKGNSG 69
FI LI+L+ SD F + A + + G+ + + A+ L E +SA S +
Sbjct: 16 FIASLIILVFSSDAFFDNAVPMFRSRGIGDMYAGTIFVGFASVLDEIALSASSLIFRHPE 75
Query: 70 IALGNAVGSALANIALILGISAMITPLKVDEVANENSLIMLGVTLYAWLLMINGEIS-RI 128
I +G GS L +A +I + EVA E +L M+ + + L M+ EI I
Sbjct: 76 IGIGAVEGSNLITMAFF----TVIVAVSYLEVAGEFTLDMIVILVLTILSMVFAEIFVHI 131
Query: 129 EGLTLVLIYGAFLYYLYRKHVKLEEIEEESRGNVIKDIAILFLSGGMVILGAELVVDSAV 188
+ ++ F+ YL +K +E G +L +S ++ L ++ +V S +
Sbjct: 132 PWFYSIALFVPFVVYLV---IKAGGSKEAGYGPQEYSNIVLIVSFFLIFLSSDTLVRSTI 188
Query: 189 KIARGAGIPEVVIGVTLVSIGTSLPELANSLTAALKGIHNVSVGNIIGADIIDILMVIGI 248
IA GI V + + + +S PE+ L + G VS+G G+ + + ++ GI
Sbjct: 189 GIASYTGINLVDLSAYGIGMVSSFPEIIMILVSLRGGRKVVSMGIFTGSTVYKMSLIPGI 248
Query: 249 ASIIRPIKVDPSIVKVTMPITVLVMAILTVSLFRNNKVGR 288
+ P I + + I V+ + +L + + GR
Sbjct: 249 IIVSEPTGFS-DIFYMLLAILVMSLLVLFLGIMSRKSQGR 287
>dbj|BAB06586.1| (AP001516) cation antiporter (Na+/Ca2+) [Bacillus halodurans]
Length = 330
Score = 69.9 bits (168), Expect = 4e-11
Identities = 75/290 (25%), Positives = 140/290 (47%), Gaps = 27/290 (9%)
Query: 10 FILGLILLIKGSDIFVNAATRIAETFGVSEFLIALVLASIATTLPEATVSAISSYKGNSG 69
FI+ I+ I + N A I E + L+ + + AT+LPE T + + N
Sbjct: 6 FIVAAIVTILTAIKLSNYADTIGEKSTLGGMLVGTIFLAGATSLPEITTTVSAIVLNNPD 65
Query: 70 IALGNAVGSALANIALILGISAMITPLKVDEVANEN-------SLIMLGVTLYAWLLMIN 122
+A+GN +GS + N+ ++ + ++ A+ + L++ VTL A L ++
Sbjct: 66 LAVGNVLGSNMFNLLILATLDLYFRRAQLFRGADTSHFFTASIGLLLAMVTLIAITLRLD 125
Query: 123 GEISRI--EGLTLVLIY--GAFLYYLYRKHVKLEE--IEEESRGNVIKDIAIL-----FL 171
+ I + L L+++Y G L R E I++E V KD+++ F
Sbjct: 126 VTLLGIGIDMLVLIVVYAFGMKLLSAVRNDPVPESQTIDQEDNRPVKKDVSLRHAMIGFA 185
Query: 172 SGGMVILGA-ELVVDSAVKIARGAGIPEVVIGVTLVSIGTSLPELANSLTAA-LKGIHNV 229
+VI+GA L+ + +IA G+ +G L++ TSLPE + A LK I N+
Sbjct: 186 ISAIVIMGAGTLLTVTGDEIAVVTGLGSSFVGSFLIAATTSLPEGVSVFVALRLKNI-NL 244
Query: 230 SVGNIIGADIIDILMVIGIASII-RPIKVDPSIVKVTMPITVLVMAILTV 278
++G+++G+++ + L ++G++ I+ RP SI+ P+ L A + +
Sbjct: 245 ALGSVLGSNLFNFL-ILGVSDILYRP----GSIIAAISPVHQLTAAAVGI 289
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.323 0.141 0.378
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 96058567
Number of Sequences: 2977
Number of extensions: 3631457
Number of successful extensions: 13043
Number of sequences better than 1.0e-10: 21
Number of HSP's better than 0.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 12955
Number of HSP's gapped (non-prelim): 45
length of query: 314
length of database: 189,106,746
effective HSP length: 59
effective length of query: 255
effective length of database: 153,796,013
effective search space: 39217983315
effective search space used: 39217983315
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.9 bits)
S2: 165 (68.7 bits)