BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB1077 (purE) DE:phosphoribosylaminoimidazole carboxylase (purE) (174 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||B75013 phosphoribosylaminoimidazole carboxylase (pure) PAB1... 342 2e-93 sp|O58058|PUR6_PYRHO PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE CA... 275 3e-73 sp|Q9WYS7|PUR6_THEMA PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE CA... 245 2e-64 gb|AAK41327.1| Phosphoribosylaminoimidazole carboxylase catalyti... 209 2e-53 sp|O06456|PUR6_SULSO PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE CA... 209 2e-53 sp|Q55498|PUR6_SYNY3 PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE CA... 205 2e-52 pir||T02535 phosphoribosylaminoimidazole carboxylase (EC 4.1.1.2... 205 3e-52 sp|O67239|PUR6_AQUAE PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE CA... 200 7e-51 sp|P15567|PUR6_SCHPO PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE (A... 200 9e-51 gb|AAC98316.1| (AF112302) phosphoribosylaminoimidazole carboxyla... 198 3e-50 emb|CAB57994.1| (AJ133372) phosphoribosylaminoimidazole carboxyl... 197 6e-50 gb|AAB09711.1| (U70673) phosphoribosylaminoimidazole carboxylase... 197 8e-50 sp|Q92233|PUR6_CRYNE PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE (A... 197 8e-50 sp|P55195|PUR6_VIGAC PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE PR... 195 3e-49 sp|O74197|PUR6_CANGA PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE (A... 193 9e-49 gb|AAD29069.1|AC007018_17 (AC007018) putative phosphoribosylamin... 193 1e-48 emb|CAC11448.1| (AL445063) probable phosphoribosylaminoimidazole... 192 3e-48 gi|6324702 phosphoribosylamino-imidazole-carboxylase; Ade2p [Sac... 185 2e-46 dbj|BAB01486.1| (AB034950) phosphoribosyl-5-aminoimidazole carbo... 185 2e-46 sp|Q92210|PUR6_CANAL PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE (A... 185 3e-46 gb|AAC49742.1| (U75582) phosphoribosylaminoimidazole carboxylase... 185 3e-46 sp|P50504|PUR6_DEBOC PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE (A... 185 3e-46 dbj|BAB04342.1| (AP001509) phosphoribosylaminoimidazole carboxyl... 184 4e-46 sp|P12044|PUR6_BACSU PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE CA... 184 6e-46 gb|AAA34407.1| (M58324) phosphoribosylaminoimidazole carboxylase... 183 7e-46 sp|P96880|PUR6_MYCTU PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE CA... 183 1e-45 sp|Q44679|PUR6_CORAM PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE CA... 181 4e-45 emb|CAA04375.1| (AJ000883) purE [Lactococcus lactis] 179 2e-44 pir||G81859 phosphoribosylaminoimidazole carboxylase (EC 4.1.1.2... 178 3e-44 pir||G81083 phosphoribosylaminoimidazole carboxylase, catalytic ... 177 6e-44 pir||C82370 phosphoribosylaminoimidazole carboxylase, catalytic ... 176 1e-43 sp|P46702|PUR6_MYCLE PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE CA... 171 3e-42 pir||C82528 phosphoribosylaminoimidazole carboxylase, catalytic ... 168 3e-41 pir||H82967 phosphoribosylaminoimidazole carboxylase, catalytic ... 167 6e-41 sp|Q01930|PUR6_PICME PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE (A... 167 8e-41 sp|P72157|PUR6_PSEAE PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE CA... 166 1e-40 sp|Q58033|PUR6_METJA PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE CA... 164 7e-40 pir||S54434 phosphoribosylaminoimidazole carboxylase (EC 4.1.1.2... 162 3e-39 sp|P09028|PUR6_ECOLI PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE CA... 158 3e-38 pir||H75568 phosphoribosylaminoimidazole carboxylase, catalytic ... 158 4e-38 sp|P43849|PUR6_HAEIN PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE CA... 157 9e-38 pir||A81341 phosphoribosylaminoimidazole carboxylase (EC 4.1.1.2... 152 3e-36 pdb|1QCZ|A Chain A, Crystal Structure Of E. Coli Pure, An Unusua... 150 7e-36 pdb|1D7A|A Chain A, Crystal Structure Of E. Coli Pure-Mononucleo... 150 7e-36 sp|P52558|PUR6_BRUME PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE CA... 144 5e-34 sp|P22348|PUR6_METSM PROBABLE PHOSPHORIBOSYLAMINOIMIDAZOLE CARBO... 136 2e-31 sp|P41654|PUR6_METTH PROBABLE PHOSPHORIBOSYLAMINOIMIDAZOLE CARBO... 123 9e-28 pir||D69052 phosphoribosylaminoimidazole carboxylase - Methanoba... 123 9e-28 gb|AAG19136.1| (AE005011) phosphoribosylaminoimidazole carboxyla... 108 3e-23 gi|11498870 phosphoribosylaminoimidazole carboxylase (purE) [Arc... 89 4e-17 >pir||B75013 phosphoribosylaminoimidazole carboxylase (pure) PAB1077 - Pyrococcus abyssi (strain Orsay) >gi|5459058|emb|CAB50544.1| (AJ248288) phosphoribosylaminoimidazole carboxylase (purE) [Pyrococcus abyssi] Length = 174 Score = 342 bits (867), Expect = 2e-93 Identities = 174/174 (100%), Positives = 174/174 (100%) Query: 1 MVKVGMPKVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEER 60 MVKVGMPKVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEER Sbjct: 1 MVKVGMPKVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEER 60 Query: 61 GIEVIIAGAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVATVGI 120 GIEVIIAGAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVATVGI Sbjct: 61 GIEVIIAGAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVATVGI 120 Query: 121 DGAKNAALLALEILSIKYPEIKEKLKKYREDMKRKVEEKSKKLEELGWRKYLEG 174 DGAKNAALLALEILSIKYPEIKEKLKKYREDMKRKVEEKSKKLEELGWRKYLEG Sbjct: 121 DGAKNAALLALEILSIKYPEIKEKLKKYREDMKRKVEEKSKKLEELGWRKYLEG 174 >sp|O58058|PUR6_PYRHO PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE CATALYTIC SUBUNIT (AIR CARBOXYLASE) (AIRC) >gi|7436513|pir||E71138 probable phosphoribosylaminoimidazole carboxylase catalytic subunit - Pyrococcus horikoshii >gi|3256711|dbj|BAA29394.1| (AP000002) 177aa long hypothetical phosphoribosylaminoimidazole carboxylase catalytic subunit [Pyrococcus horikoshii] Length = 177 Score = 275 bits (695), Expect = 3e-73 Identities = 135/171 (78%), Positives = 155/171 (89%) Query: 2 VKVGMPKVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERG 61 +K P VGIIMGSDSDLPVMKEAA++LE+F V YE+ +ISAHRTPER +EYA+ AEERG Sbjct: 5 MKSEKPLVGIIMGSDSDLPVMKEAARILEEFGVPYEITIISAHRTPERAYEYAKKAEERG 64 Query: 62 IEVIIAGAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVATVGID 121 IEVIIAGAGGAAHLPG++A+LT++PVIGVPIKSKALNGLDSLLSIVQMP GIPVATV ID Sbjct: 65 IEVIIAGAGGAAHLPGIIASLTVLPVIGVPIKSKALNGLDSLLSIVQMPSGIPVATVAID 124 Query: 122 GAKNAALLALEILSIKYPEIKEKLKKYREDMKRKVEEKSKKLEELGWRKYL 172 AKNAALLAL IL IKYPEIKEKL++Y +DMKRKVEEK+K+LEE+GW +YL Sbjct: 125 NAKNAALLALRILGIKYPEIKEKLRRYMKDMKRKVEEKAKRLEEMGWERYL 175 >sp|Q9WYS7|PUR6_THEMA PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE CATALYTIC SUBUNIT (AIR CARBOXYLASE) (AIRC) >gi|7436511|pir||G72374 phosphoribosylaminoimidazole carboxylase, catalytic subunit - Thermotoga maritima (strain MSB8) >gi|4980964|gb|AAD35541.1|AE001723_11 (AE001723) phosphoribosylaminoimidazole carboxylase, catalytic subunit [Thermotoga maritima] Length = 171 Score = 245 bits (619), Expect = 2e-64 Identities = 114/167 (68%), Positives = 148/167 (88%) Query: 6 MPKVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVI 65 MP+VGIIMGSDSDLPVMK+AA++LE+F +DYE+ ++SAHRTP+R+ EYA+ AEERGIEVI Sbjct: 1 MPRVGIIMGSDSDLPVMKQAAEILEEFGIDYEITIVSAHRTPDRMFEYAKNAEERGIEVI 60 Query: 66 IAGAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVATVGIDGAKN 125 IAGAGGAAHLPG++A++T +PVIGVP+K+ LNGLDSL SIVQMP G+PVATV I+ AKN Sbjct: 61 IAGAGGAAHLPGMVASITHLPVIGVPVKTSTLNGLDSLFSIVQMPGGVPVATVAINNAKN 120 Query: 126 AALLALEILSIKYPEIKEKLKKYREDMKRKVEEKSKKLEELGWRKYL 172 A +LA IL IKYPEI K+K+Y+E MKR+V EK+++LE++G+++YL Sbjct: 121 AGILAASILGIKYPEIARKVKEYKERMKREVLEKAQRLEQIGYKEYL 167 >gb|AAK41327.1| Phosphoribosylaminoimidazole carboxylase catalytic subunit (purE) [Sulfolobus solfataricus] Length = 158 Score = 209 bits (526), Expect = 2e-53 Identities = 102/151 (67%), Positives = 126/151 (82%) Query: 6 MPKVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVI 65 MPKV +IMGS +D M+EA ++L+ F +DYE +V+SAHRTPE + +YA+ AE+RGIEVI Sbjct: 1 MPKVAVIMGSKNDWEYMREAVEILKQFGIDYEARVVSAHRTPEFMMQYAKEAEKRGIEVI 60 Query: 66 IAGAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVATVGIDGAKN 125 IAGAGGAAHLPG++A+LT +PVIGVPI SK LNGLDSLLSIVQMP G+PVATV I GAKN Sbjct: 61 IAGAGGAAHLPGMVASLTSLPVIGVPIPSKNLNGLDSLLSIVQMPYGVPVATVAIGGAKN 120 Query: 126 AALLALEILSIKYPEIKEKLKKYREDMKRKV 156 AALLA+ IL IKY E+ +K+KK+ EDM+ V Sbjct: 121 AALLAIRILGIKYKELADKIKKFSEDMRNDV 151 >sp|O06456|PUR6_SULSO PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE CATALYTIC SUBUNIT (AIR CARBOXYLASE) (AIRC) >gi|2104667|emb|CAA73604.1| (Y13143) purE [Sulfolobus solfataricus] Length = 158 Score = 209 bits (526), Expect = 2e-53 Identities = 102/151 (67%), Positives = 126/151 (82%) Query: 6 MPKVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVI 65 MPKV +IMGS +D M+EA ++L+ F +DYE +V+SAHRTPE + +YA+ AE+RGIEVI Sbjct: 1 MPKVAVIMGSKNDWEYMREAVEILKQFGIDYEARVVSAHRTPEFMMQYAKEAEKRGIEVI 60 Query: 66 IAGAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVATVGIDGAKN 125 IAGAGGAAHLPG++A+LT +PVIGVPI SK LNGLDSLLSIVQMP G+PVATV I GAKN Sbjct: 61 IAGAGGAAHLPGMVASLTSLPVIGVPIPSKNLNGLDSLLSIVQMPYGVPVATVAIGGAKN 120 Query: 126 AALLALEILSIKYPEIKEKLKKYREDMKRKV 156 AALLA+ IL IKY E+ +K+KK+ EDM+ V Sbjct: 121 AALLAIRILGIKYKELADKIKKFSEDMRNDV 151 >sp|Q55498|PUR6_SYNY3 PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE CATALYTIC SUBUNIT (AIR CARBOXYLASE) (AIRC) >gi|7436515|pir||S76001 phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) catalytic chain - Synechocystis sp. (strain PCC 6803) >gi|1001361|dbj|BAA10848.1| (D64006) phosphoribosylaminoimidazole carboxylase [Synechocystis sp.] Length = 176 Score = 205 bits (517), Expect = 2e-52 Identities = 102/167 (61%), Positives = 131/167 (78%) Query: 7 PKVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVII 66 P VGIIMGSDSDLP M A V E+F V E+ +ISAHRTPER+ EYA+TA +RG+ +II Sbjct: 6 PLVGIIMGSDSDLPTMAAAIAVCEEFAVPTEVAIISAHRTPERMVEYAQTAHQRGLRIII 65 Query: 67 AGAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVATVGIDGAKNA 126 AGAGGAAHLPG++AALT +PVIGVP+++K L G+DSL SIVQMP GIPVATV I AKNA Sbjct: 66 AGAGGAAHLPGMVAALTPLPVIGVPVQTKTLQGVDSLYSIVQMPGGIPVATVAIGNAKNA 125 Query: 127 ALLALEILSIKYPEIKEKLKKYREDMKRKVEEKSKKLEELGWRKYLE 173 LLA++IL+ P + EK+++YR+ ++ V +K +LE LG+R YL+ Sbjct: 126 GLLAVQILASHNPVLLEKVQQYRQSLETMVLDKQAELERLGYRAYLD 172 >pir||T02535 phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) - Arabidopsis thaliana >gi|3236251|gb|AAC23639.1| (AC004684) putative phosphoribosylaminoimidazole carboxylase [Arabidopsis thaliana] Length = 645 Score = 205 bits (516), Expect = 3e-52 Identities = 97/166 (58%), Positives = 134/166 (80%) Query: 7 PKVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVII 66 P+V IIMGSD+DLPVMK+AAK+L+ F V +E+K++SAHRTPE ++ YA +A RG++VII Sbjct: 478 PRVAIIMGSDTDLPVMKDAAKILDLFGVTHEVKIVSAHRTPEMMYTYATSAHSRGVQVII 537 Query: 67 AGAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVATVGIDGAKNA 126 AGAGGAAHLPG++A+LT +PVIGVP+++ L+G+DSLLSIVQMP G+PVATV I+ A NA Sbjct: 538 AGAGGAAHLPGMVASLTPLPVIGVPVRATRLDGVDSLLSIVQMPRGVPVATVAINNATNA 597 Query: 127 ALLALEILSIKYPEIKEKLKKYREDMKRKVEEKSKKLEELGWRKYL 172 ALLA+ +L I ++ ++++Y+EDM+ + K +KLE GW YL Sbjct: 598 ALLAVRMLGISDTDLVSRMRQYQEDMRDENLNKGEKLETEGWESYL 643 >sp|O67239|PUR6_AQUAE PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE CATALYTIC SUBUNIT (AIR CARBOXYLASE) (AIRC) >gi|7436514|pir||D70401 phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) catalytic chain - Aquifex aeolicus >gi|2983633|gb|AAC07201.1| (AE000727) phosphoribosylaminoimidazole carboxylase [Aquifex aeolicus] Length = 167 Score = 200 bits (504), Expect = 7e-51 Identities = 100/159 (62%), Positives = 128/159 (79%) Query: 7 PKVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVII 66 P VG+IMGS SD MK+A +VL++F V +E+KV+SAHRTPE ++EYA+TA ERGIEVII Sbjct: 3 PLVGVIMGSISDWEYMKKAVEVLKEFGVPHEVKVVSAHRTPELMYEYAKTARERGIEVII 62 Query: 67 AGAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVATVGIDGAKNA 126 AGAGG+AHLPG+ A++T +PVIGVPI +K L G+DSL SIVQMP GIPVATV I A NA Sbjct: 63 AGAGGSAHLPGMTASMTTLPVIGVPIPTKNLGGVDSLYSIVQMPAGIPVATVAIGNATNA 122 Query: 127 ALLALEILSIKYPEIKEKLKKYREDMKRKVEEKSKKLEE 165 LLA+ ILSIKYPE +KL +Y E +K KV + +++L++ Sbjct: 123 GLLAVRILSIKYPEYAKKLDEYTEKLKEKVAKMNEELQK 161 >sp|P15567|PUR6_SCHPO PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE (AIR CARBOXYLASE) (AIRC) >gi|68001|pir||DEZPP phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) - fission yeast (Schizosaccharomyces pombe) >gi|4902|emb|CAA32650.1| (X14488) phosphoribosylaminoimidazole carboxylase (AA 1 - 552) [Schizosaccharomyces pombe] >gi|173342|gb|AAA35285.1| (M37264) phosphoribosylaminoimidazole carboxylase (ade6) [Schizosaccharomyces pombe] >gi|4176553|emb|CAA22866.1| (AL035259) phosphoribosylaminoimidazole carboxylase [Schizosaccharomyces pombe] Length = 552 Score = 200 bits (503), Expect = 9e-51 Identities = 96/168 (57%), Positives = 130/168 (77%) Query: 4 VGMPKVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIE 63 V P VGIIMGSDSDL MK+AA +L++F+V YE+ ++SAHRTP+R+ YARTA RG+ Sbjct: 383 VESPVVGIIMGSDSDLSKMKDAAVILDEFKVPYELTIVSAHRTPDRMVTYARTAASRGLR 442 Query: 64 VIIAGAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVATVGIDGA 123 VIIAGAGGAAHLPG++AA+T +PVIGVP+K L+G+DSL SIVQMP G+PVATV I+ + Sbjct: 443 VIIAGAGGAAHLPGMVAAMTPLPVIGVPVKGSTLDGVDSLHSIVQMPRGVPVATVAINNS 502 Query: 124 KNAALLALEILSIKYPEIKEKLKKYREDMKRKVEEKSKKLEELGWRKY 171 +NA +LA IL+ P + ++ + ++MK V EK+ KLE++GW+ Y Sbjct: 503 QNAGILACRILATFQPSLLAAMESFMDNMKEIVLEKADKLEKVGWKNY 550 >gb|AAC98316.1| (AF112302) phosphoribosylaminoimidazole carboxylase [Filobasidiella neoformans] Length = 582 Score = 198 bits (498), Expect = 3e-50 Identities = 98/167 (58%), Positives = 126/167 (74%) Query: 7 PKVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVII 66 P VGIIMGSDSDLPVM A K+LE F V YE+ + SAHRTPER+ +YA+TA +RG+ II Sbjct: 412 PLVGIIMGSDSDLPVMHPATKILEKFGVPYELTITSAHRTPERMVKYAKTAADRGLRAII 471 Query: 67 AGAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVATVGIDGAKNA 126 AGAGGAAHLPG++A+ T +PVIGVP+K+ L+G+DSL SIVQMP GIP ATVGI+ + NA Sbjct: 472 AGAGGAAHLPGMVASETSLPVIGVPVKASVLDGVDSLYSIVQMPRGIPCATVGINNSTNA 531 Query: 127 ALLALEILSIKYPEIKEKLKKYREDMKRKVEEKSKKLEELGWRKYLE 173 ALLA+ IL P + + ++Y + ++ +V K LEE GW KY+E Sbjct: 532 ALLAVRILGTSVPALNKATEEYSKALEEEVLAKVDILEEEGWDKYIE 578 >emb|CAB57994.1| (AJ133372) phosphoribosylaminoimidazole carboxylase [Zygosaccharomyces rouxii] >gi|11414818|emb|CAC17413.1| (AJ251115) phosphoribosyl-aminoimidazole carboxylase [Zygosaccharomyces rouxii] Length = 570 Score = 197 bits (496), Expect = 6e-50 Identities = 94/168 (55%), Positives = 131/168 (77%) Query: 5 GMPKVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEV 64 G P VGIIMGSDSDLPVM +A +LE+FEV +E+ ++SAHRTP+R+++YA A RG++ Sbjct: 400 GKPVVGIIMGSDSDLPVMSKACAILEEFEVPFEVTIVSAHRTPQRMNKYASEASSRGLKA 459 Query: 65 IIAGAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVATVGIDGAK 124 IIAGAGGAAHLPG++AA+T +PVIGVP+K +L+G+DSL SIVQMP G+PVATV I+ + Sbjct: 460 IIAGAGGAAHLPGMVAAMTPLPVIGVPVKGSSLDGVDSLHSIVQMPRGVPVATVAINNST 519 Query: 125 NAALLALEILSIKYPEIKEKLKKYREDMKRKVEEKSKKLEELGWRKYL 172 NAALLA+ + P+ +K+++Y + +V EK+KKLE G++ Y+ Sbjct: 520 NAALLAVRFIGAFEPKYHKKMQQYLLKQEVEVLEKAKKLENSGYKNYM 567 >gb|AAB09711.1| (U70673) phosphoribosylaminoimidazole carboxylase [Filobasidiella neoformans] Length = 583 Score = 197 bits (495), Expect = 8e-50 Identities = 98/167 (58%), Positives = 125/167 (74%) Query: 7 PKVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVII 66 P VGIIMGSDSDLPVM A K+LE F V YE+ + SAHRTPER+ +YA+TA RG+ II Sbjct: 413 PLVGIIMGSDSDLPVMHPATKILEKFGVPYELTITSAHRTPERMVKYAKTAAGRGLRAII 472 Query: 67 AGAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVATVGIDGAKNA 126 AGAGGAAHLPG++A+ T +PVIGVP+K+ L+G+DSL SIVQMP GIP ATVGI+ + NA Sbjct: 473 AGAGGAAHLPGMVASETSLPVIGVPVKASVLDGVDSLYSIVQMPRGIPCATVGINNSTNA 532 Query: 127 ALLALEILSIKYPEIKEKLKKYREDMKRKVEEKSKKLEELGWRKYLE 173 ALLA+ IL P + + ++Y + ++ +V K LEE GW KY+E Sbjct: 533 ALLAIRILGTSVPALNKATEEYSKALEEEVLAKVDILEEEGWDKYIE 579 >sp|Q92233|PUR6_CRYNE PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE (AIR CARBOXYLASE) (AIRC) Length = 582 Score = 197 bits (495), Expect = 8e-50 Identities = 98/167 (58%), Positives = 125/167 (74%) Query: 7 PKVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVII 66 P VGIIMGSDSDLPVM A K+LE F V YE+ + SAHRTPER+ +YA+TA RG+ II Sbjct: 412 PLVGIIMGSDSDLPVMHPATKILEKFGVPYELTITSAHRTPERMVKYAKTAAGRGLRAII 471 Query: 67 AGAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVATVGIDGAKNA 126 AGAGGAAHLPG++A+ T +PVIGVP+K+ L+G+DSL SIVQMP GIP ATVGI+ + NA Sbjct: 472 AGAGGAAHLPGMVASETSLPVIGVPVKASVLDGVDSLYSIVQMPRGIPCATVGINNSTNA 531 Query: 127 ALLALEILSIKYPEIKEKLKKYREDMKRKVEEKSKKLEELGWRKYLE 173 ALLA+ IL P + + ++Y + ++ +V K LEE GW KY+E Sbjct: 532 ALLAIRILGTSVPALNKATEEYSKALEEEVLAKVDILEEEGWDKYIE 578 >sp|P55195|PUR6_VIGAC PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE PRECURSOR (AIR CARBOXYLASE) (AIRC) >gi|629656|pir||S43322 phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) - moth bean >gi|349159|gb|AAC37400.1| (L22584) 5-aminoimidazole ribonucleotide carboxylase [Vigna aconitifolia] Length = 557 Score = 195 bits (490), Expect = 3e-49 Identities = 92/165 (55%), Positives = 127/165 (76%) Query: 9 VGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVIIAG 68 +G IMGSDSDLPVMK AA+++E F V +E++++SAHRTPE + YA +A ERG +VIIAG Sbjct: 391 LGFIMGSDSDLPVMKSAAEMMEMFGVPHEVRIVSAHRTPELMFCYASSAHERGYQVIIAG 450 Query: 69 AGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVATVGIDGAKNAAL 128 AGGAAHLPG++A+LT +PV+GVP+++ L+GLDSLLSIVQMP G+PVATV ++ A NA L Sbjct: 451 AGGAAHLPGMVASLTPLPVVGVPVRASTLDGLDSLLSIVQMPRGVPVATVAVNNATNAGL 510 Query: 129 LALEILSIKYPEIKEKLKKYREDMKRKVEEKSKKLEELGWRKYLE 173 LA+ +L + + ++ +Y+ED K V + KLE+ GW YL+ Sbjct: 511 LAVRMLGVANDNLLSRMSQYQEDQKEAVLREGDKLEKHGWESYLK 555 >sp|O74197|PUR6_CANGA PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE (AIR CARBOXYLASE) (AIRC) >gi|3342244|gb|AAC27548.1| (AF030388) aminoimidazole ribonucleotide carboxylase [Candida glabrata] Length = 570 Score = 193 bits (486), Expect = 9e-49 Identities = 94/171 (54%), Positives = 130/171 (75%) Query: 3 KVGMPKVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGI 62 +V P VG+IMGSDSDLPVM A K+LE FEV +E+ ++SAHRTP R+++YA A RGI Sbjct: 398 EVRKPLVGVIMGSDSDLPVMSAACKMLEQFEVPFEVTIVSAHRTPYRMNKYASEAVSRGI 457 Query: 63 EVIIAGAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVATVGIDG 122 +VIIAGAGGAAHLPG++AA+ +PVIGVP+K L+G+DSL SIVQMP G+PVATV I+ Sbjct: 458 KVIIAGAGGAAHLPGMVAAIAPVPVIGVPVKGSFLDGVDSLHSIVQMPRGVPVATVAINN 517 Query: 123 AKNAALLALEILSIKYPEIKEKLKKYREDMKRKVEEKSKKLEELGWRKYLE 173 + NA +LA+ +L I + +K++++ + +V +K+ KLE +G+ KYLE Sbjct: 518 STNAGILAVRMLGIHNYDYVKKMEEFLNKQEEEVLQKAAKLESIGYEKYLE 568 >gb|AAD29069.1|AC007018_17 (AC007018) putative phosphoribosylaminoimidazole carboxylase [Arabidopsis thaliana] Length = 162 Score = 193 bits (485), Expect = 1e-48 Identities = 92/160 (57%), Positives = 128/160 (79%) Query: 13 MGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVIIAGAGGA 72 MGSD+DL VMK+AAK+L+ F V +E+K++SAHRTPE ++ YA +A RG++VIIAGAGGA Sbjct: 1 MGSDTDLLVMKDAAKILDMFGVTHEVKIVSAHRTPEMMYTYATSAHSRGVQVIIAGAGGA 60 Query: 73 AHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVATVGIDGAKNAALLALE 132 AHLPG++A+LT +PVIGVP+++ L+G+DSLLSIVQMP G+PVATV I+ A NAALLA+ Sbjct: 61 AHLPGMVASLTPLPVIGVPVQATRLDGVDSLLSIVQMPRGVPVATVAINNATNAALLAVR 120 Query: 133 ILSIKYPEIKEKLKKYREDMKRKVEEKSKKLEELGWRKYL 172 +L I ++ ++++Y+EDM+ + K +KLE GW YL Sbjct: 121 MLGISDNDLVSRMRQYQEDMRDENLNKGEKLETQGWESYL 160 >emb|CAC11448.1| (AL445063) probable phosphoribosylaminoimidazole carboxylase catalytic subunit [Thermoplasma acidophilum] Length = 160 Score = 192 bits (482), Expect = 3e-48 Identities = 95/159 (59%), Positives = 124/159 (77%), Gaps = 2/159 (1%) Query: 6 MPKVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVI 65 MP+V +IMGS SD MK A L +D +K++SAHRTPE + ++A +A ++GIEVI Sbjct: 4 MPRVAVIMGSSSDYETMKPAVDFLRSMHIDVVLKIVSAHRTPEYMFQFASSARDQGIEVI 63 Query: 66 IAGAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVATVGIDGAKN 125 IAGAGGAAHLPG++A++T +PVIGVP+ S+ LNGLDSLLSIVQMP GIPVATV I +KN Sbjct: 64 IAGAGGAAHLPGMVASMTTLPVIGVPVPSRNLNGLDSLLSIVQMPSGIPVATVAIGNSKN 123 Query: 126 AALLALEILSIKYPEIKEKLKKYREDMKRKVEEKSKKLE 164 AA+LA ILSIKYPEI++ +KKY +D + +V ++KLE Sbjct: 124 AAILACRILSIKYPEIEKAIKKYMDDERDRV--LNEKLE 160 >gi|6324702 phosphoribosylamino-imidazole-carboxylase; Ade2p [Saccharomyces cerevisiae] >gi|131630|sp|P21264|PUR6_YEAST PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE (AIR CARBOXYLASE) (AIRC) >gi|68002|pir||DEBYP phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) - yeast (Saccharomyces cerevisiae) >gi|171003|gb|AAA34401.1| (M59824) phosphoribosyl aminoimidazole carboxylase [Saccharomyces cerevisiae] >gi|1050830|emb|CAA62125.1| (X90518) ORF O3293 [Saccharomyces cerevisiae] >gi|1164972|emb|CAA64047.1| (X94335) YOR3293c [Saccharomyces cerevisiae] >gi|1420332|emb|CAA99327.1| (Z75036) ORF YOR128c [Saccharomyces cerevisiae] >gi|3243009|gb|AAC23867.1| (AF069717) phosphoribosylaminoimidazole carboxylase [Expression vector pBEVY-A] >gi|3243012|gb|AAC23869.1| (AF069718) phosphoribosylaminoimidazole carboxylase [Expression vector pBEVY-GA] >gi|3243116|gb|AAC40224.1| (AF039102) phosphoribosylamino-imidazole-carboxylase [Integrating expression vector YIpDCE1] Length = 571 Score = 185 bits (466), Expect = 2e-46 Identities = 93/167 (55%), Positives = 124/167 (73%) Query: 7 PKVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVII 66 P VGIIMGSDSDLPVM A VL+DF V +E+ ++SAHRTP R+ YA +A +RGI+ II Sbjct: 403 PLVGIIMGSDSDLPVMSAACAVLKDFGVPFEVTIVSAHRTPHRMSAYAISASKRGIKTII 462 Query: 67 AGAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVATVGIDGAKNA 126 AGAGGAAHLPG++AA+T +PVIGVP+K L+G+DSL SIVQMP G+PVATV I+ + NA Sbjct: 463 AGAGGAAHLPGMVAAMTPLPVIGVPVKGSCLDGVDSLHSIVQMPRGVPVATVAINNSTNA 522 Query: 127 ALLALEILSIKYPEIKEKLKKYREDMKRKVEEKSKKLEELGWRKYLE 173 ALLA+ +L K++++ + +V K++KLE +G+ YLE Sbjct: 523 ALLAVRLLGAYDSSYTTKMEQFLLKQEEEVLVKAQKLETVGYEAYLE 569 >dbj|BAB01486.1| (AB034950) phosphoribosyl-5-aminoimidazole carboxylase [Candida boidinii] Length = 572 Score = 185 bits (466), Expect = 2e-46 Identities = 93/166 (56%), Positives = 124/166 (74%) Query: 7 PKVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVII 66 P VG+IMGSDSDLPVM +L+ F V +E+ ++SAHRTPER+ +YA A RGI+ II Sbjct: 402 PLVGVIMGSDSDLPVMSLGCNILKQFGVPFEVTIVSAHRTPERMAKYAADAPARGIKAII 461 Query: 67 AGAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVATVGIDGAKNA 126 AGAGGAAHLPG++AA+T +PVIGVP+K L+G+DSL SIVQMP GIPVATV I+ A NA Sbjct: 462 AGAGGAAHLPGMVAAMTPLPVIGVPVKGSTLDGVDSLHSIVQMPRGIPVATVAINNATNA 521 Query: 127 ALLALEILSIKYPEIKEKLKKYREDMKRKVEEKSKKLEELGWRKYL 172 ALLA+ IL + ++ Y + M+++V +K++KLE+ G+ YL Sbjct: 522 ALLAIRILGASDSKWFTEMDAYMKGMEKEVLQKAEKLEKGGYEDYL 567 >sp|Q92210|PUR6_CANAL PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE (AIR CARBOXYLASE) (AIRC) >gi|1658379|gb|AAC49755.1| (U69606) phosphoribosylaminoimidazole carboxylase [Candida albicans] Length = 568 Score = 185 bits (465), Expect = 3e-46 Identities = 93/166 (56%), Positives = 125/166 (75%) Query: 7 PKVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVII 66 P VGIIMGSDSDLPVM A++L+ F V +E+ ++SAHRTP R+ EYA A +RG++ II Sbjct: 397 PLVGIIMGSDSDLPVMAVGARILKQFGVPFELTIVSAHRTPHRMSEYAIEAPKRGLKCII 456 Query: 67 AGAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVATVGIDGAKNA 126 AGAGGAAHLPG++AA+T +PVIGVP+K L+G+DSL SIVQMP GIPVATV I+ + NA Sbjct: 457 AGAGGAAHLPGMVAAMTPLPVIGVPVKGSTLDGVDSLHSIVQMPRGIPVATVAINNSTNA 516 Query: 127 ALLALEILSIKYPEIKEKLKKYREDMKRKVEEKSKKLEELGWRKYL 172 ALLA+ IL + ++ +Y +M+ +V K++ LEE+G+ YL Sbjct: 517 ALLAIRILGAYDSKWLTEMNQYMLNMETEVLGKAETLEEIGYEDYL 562 >gb|AAC49742.1| (U75582) phosphoribosylaminoimidazole carboxylase [Candida albicans] Length = 568 Score = 185 bits (465), Expect = 3e-46 Identities = 93/166 (56%), Positives = 125/166 (75%) Query: 7 PKVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVII 66 P VGIIMGSDSDLPVM A++L+ F V +E+ ++SAHRTP R+ EYA A +RG++ II Sbjct: 397 PLVGIIMGSDSDLPVMAVGARILKQFGVPFELTIVSAHRTPHRMSEYAIEAPKRGLKCII 456 Query: 67 AGAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVATVGIDGAKNA 126 AGAGGAAHLPG++AA+T +PVIGVP+K L+G+DSL SIVQMP GIPVATV I+ + NA Sbjct: 457 AGAGGAAHLPGMVAAMTPLPVIGVPVKGSTLDGVDSLHSIVQMPRGIPVATVAINNSTNA 516 Query: 127 ALLALEILSIKYPEIKEKLKKYREDMKRKVEEKSKKLEELGWRKYL 172 ALLA+ IL + ++ +Y +M+ +V K++ LEE+G+ YL Sbjct: 517 ALLAIRILGAYDSKWLTEMNQYMLNMETEVLGKAETLEEIGYEDYL 562 >sp|P50504|PUR6_DEBOC PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE (AIR CARBOXYLASE) (AIRC) >gi|2133234|pir||S60392 phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) - yeast (Schwanniomyces occidentalis) >gi|995583|gb|AAA96380.1| (U23210) phosphoribosylaminoimidazole carboxylase [Debaryomyces occidentalis] Length = 557 Score = 185 bits (464), Expect = 3e-46 Identities = 92/165 (55%), Positives = 125/165 (75%) Query: 7 PKVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVII 66 P V IIMGSDSDLPVM A +L+ F V +E+ ++SAHRTP R+ +YA A +RG++VII Sbjct: 393 PLVSIIMGSDSDLPVMSVGANILKRFGVPFELTIVSAHRTPHRMTQYAIEAPKRGLKVII 452 Query: 67 AGAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVATVGIDGAKNA 126 AGAGGAAHLPG++AA+T +PVIGVP+K L+G+DSL SIVQMP GIPVATV I+ + NA Sbjct: 453 AGAGGAAHLPGMVAAMTPLPVIGVPVKGSTLDGVDSLHSIVQMPRGIPVATVAINNSTNA 512 Query: 127 ALLALEILSIKYPEIKEKLKKYREDMKRKVEEKSKKLEELGWRKY 171 ALLA+ IL + ++ +Y +M+ +V K+++LEE+G+ KY Sbjct: 513 ALLAVRILGAYDYKWLNEMNQYMNNMENEVLAKAERLEEVGYEKY 557 >dbj|BAB04342.1| (AP001509) phosphoribosylaminoimidazole carboxylase I [Bacillus halodurans] Length = 161 Score = 184 bits (463), Expect = 4e-46 Identities = 93/159 (58%), Positives = 124/159 (77%), Gaps = 2/159 (1%) Query: 7 PKVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVII 66 P VG+IMGS SD M+ A ++LE+ EV YE KV+SAHRTP+ + +YA TA+ERG++VII Sbjct: 3 PVVGVIMGSTSDWETMQHACEILEELEVPYEKKVVSAHRTPDLMFQYAETAQERGLKVII 62 Query: 67 AGAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVATVGID--GAK 124 AGAGGAAHLPG++AA T++PVIGVP++SKALNGLDSLLSIVQMP G+PVATV I GA Sbjct: 63 AGAGGAAHLPGMVAAKTVVPVIGVPVQSKALNGLDSLLSIVQMPGGVPVATVAIGKAGAT 122 Query: 125 NAALLALEILSIKYPEIKEKLKKYREDMKRKVEEKSKKL 163 NA LLA +++ ++ E+++ RE +++ V E S+ L Sbjct: 123 NAGLLAAQMIGAFDHQVAERVRLRREKVEQAVLESSESL 161 >sp|P12044|PUR6_BACSU PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE CATALYTIC SUBUNIT (AIR CARBOXYLASE) (AIRC) >gi|67998|pir||DEBSPE phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) catalytic chain - Bacillus subtilis >gi|143364|gb|AAA22674.1| (J02732) phosphoribosyl aminoimidazole carboxylase I (PUR-E) [Bacillus subtilis] >gi|2632956|emb|CAB12462.1| (Z99107) phosphoribosylaminoimidazole carboxylase I [Bacillus subtilis] Length = 162 Score = 184 bits (462), Expect = 6e-46 Identities = 98/159 (61%), Positives = 119/159 (74%), Gaps = 2/159 (1%) Query: 7 PKVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVII 66 P VGIIMGS SD MK A +L++ V YE KV+SAHRTP+ + EYA TA ERGI+VII Sbjct: 3 PLVGIIMGSTSDWETMKHACDILDELNVPYEKKVVSAHRTPDFMFEYAETARERGIKVII 62 Query: 67 AGAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVAT--VGIDGAK 124 AGAGGAAHLPG+ AA T +PVIGVP++SKALNG+DSLLSIVQMP G+PVAT +G GA Sbjct: 63 AGAGGAAHLPGMTAAKTTLPVIGVPVQSKALNGMDSLLSIVQMPGGVPVATTSIGKAGAV 122 Query: 125 NAALLALEILSIKYPEIKEKLKKYREDMKRKVEEKSKKL 163 NA LLA +ILS ++ KL + RE+ K+ V E S +L Sbjct: 123 NAGLLAAQILSAFDEDLARKLDERRENTKQTVLESSDQL 161 >gb|AAA34407.1| (M58324) phosphoribosylaminoimidazole carboxylase [Saccharomyces cerevisiae] Length = 570 Score = 183 bits (461), Expect = 7e-46 Identities = 91/167 (54%), Positives = 123/167 (73%) Query: 7 PKVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVII 66 P VG+IMGSDSDLPVM A VL+DF V +E+ ++SAHRTP R+ YA +A +RGI+ II Sbjct: 402 PLVGVIMGSDSDLPVMSAACAVLKDFGVTFELTIVSAHRTPHRMSAYAISASKRGIKTII 461 Query: 67 AGAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVATVGIDGAKNA 126 AGAGGAAHLPG++AA+T +PVIGVP+K L+G+DSL S VQMP G+PVATV I+ + NA Sbjct: 462 AGAGGAAHLPGMVAAMTPLPVIGVPVKGSCLDGVDSLHSTVQMPRGVPVATVAINNSTNA 521 Query: 127 ALLALEILSIKYPEIKEKLKKYREDMKRKVEEKSKKLEELGWRKYLE 173 ALLA+ +L K++++ + +V K++KLE +G+ YLE Sbjct: 522 ALLAVRLLGAYDSSYTTKMEQFLLKQEEEVLVKAQKLETVGYEAYLE 568 >sp|P96880|PUR6_MYCTU PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE CATALYTIC SUBUNIT (AIR CARBOXYLASE) (AIRC) >gi|7436516|pir||D70979 probable purE protein - Mycobacterium tuberculosis (strain H37RV) >gi|1877330|emb|CAB07078.1| (Z92771) purE [Mycobacterium tuberculosis] Length = 174 Score = 183 bits (459), Expect = 1e-45 Identities = 90/160 (56%), Positives = 120/160 (74%) Query: 7 PKVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVII 66 P+VG+IMGSDSD PVM +AA L +F++ E++V+SAHRTPE + YAR A ERG+EVII Sbjct: 8 PRVGVIMGSDSDWPVMADAAAALAEFDIPAEVRVVSAHRTPEAMFSYARGAAERGLEVII 67 Query: 67 AGAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVATVGIDGAKNA 126 AGAGGAAHLPG++AA T +PVIGVP+ L+GLDSLLSIVQMP G+PVATV I GA NA Sbjct: 68 AGAGGAAHLPGMVAAATPLPVIGVPVPLGRLDGLDSLLSIVQMPAGVPVATVSIGGAGNA 127 Query: 127 ALLALEILSIKYPEIKEKLKKYREDMKRKVEEKSKKLEEL 166 LLA+ +L P+++ ++ +++ + V K +L+ L Sbjct: 128 GLLAVRMLGAANPQLRARIVAFQDRLADVVAAKDAELQRL 167 >sp|Q44679|PUR6_CORAM PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE CATALYTIC SUBUNIT (AIR CARBOXYLASE) (AIRC) >gi|1418345|emb|CAA62599.1| (X91189) 5'-phosphoribosyl-5-amino-4-imidasol carboxylase [Corynebacterium ammoniagenes] Length = 177 Score = 181 bits (455), Expect = 4e-45 Identities = 92/170 (54%), Positives = 123/170 (72%), Gaps = 8/170 (4%) Query: 7 PKVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVII 66 P VG+IMGSDSD P ++ AA+VL++F V +E+ V+SAHRTPE++ +YA+ A RGI+VI+ Sbjct: 4 PLVGLIMGSDSDWPTVEPAAEVLDEFGVPFEVGVVSAHRTPEKMLDYAKQAHTRGIKVIV 63 Query: 67 AGAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVATVGIDGAKNA 126 A AGGAAHLPG++AA T +PVIG+P K L GLDSLLSIVQMP G+PVATV I GAKNA Sbjct: 64 ACAGGAAHLPGMVAAATPLPVIGIPRALKDLEGLDSLLSIVQMPAGVPVATVSIGGAKNA 123 Query: 127 ALLALEILSIKYPEIKEKLKKYREDM--------KRKVEEKSKKLEELGW 168 LLA+ L ++Y E+ E++ Y+E+M RK+ +K+ W Sbjct: 124 GLLAIRTLGVQYSELVERMADYQENMADYQPKIWPRKLSKKTPIFAPSSW 173 >emb|CAA04375.1| (AJ000883) purE [Lactococcus lactis] Length = 161 Score = 179 bits (449), Expect = 2e-44 Identities = 94/160 (58%), Positives = 119/160 (73%), Gaps = 2/160 (1%) Query: 6 MPKVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVI 65 M +V IIMG SD MKE AK+L+DF + YE KV+SAHRTP + E++ A ERG +VI Sbjct: 1 MAEVAIIMGCSSDWATMKETAKILDDFGLAYEKKVVSAHRTPALMAEFSSQARERGYKVI 60 Query: 66 IAGAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVAT--VGIDGA 123 IAGAGGAAHLPG+++A T++PVIGVPIKS+AL+GLDSL SIVQMP G+PVAT +G GA Sbjct: 61 IAGAGGAAHLPGMVSAQTLVPVIGVPIKSRALSGLDSLYSIVQMPAGVPVATMAIGEAGA 120 Query: 124 KNAALLALEILSIKYPEIKEKLKKYREDMKRKVEEKSKKL 163 KNAAL AL++L+ + +KL YR + VEE +K L Sbjct: 121 KNAALFALQLLANTNENLIQKLLVYRAAAQEMVEESNKAL 160 >pir||G81859 phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) catalytic subunit NMA1651 [imported] - Neisseria meningitidis (group A strain Z2491) >gi|7380293|emb|CAB84879.1| (AL162756) phosphoribosylaminoimidazole carboxylase catalytic subunit [Neisseria meningitidis Z2491] Length = 161 Score = 178 bits (447), Expect = 3e-44 Identities = 92/163 (56%), Positives = 125/163 (76%), Gaps = 4/163 (2%) Query: 6 MPKVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVI 65 M ++GIIMGS+SD PVM++AA+ LE+F V+YE +V+SAHRTP+ + +YA TA RGI+ I Sbjct: 1 MIQIGIIMGSNSDWPVMRQAAQFLEEFGVEYEARVVSAHRTPDLMFQYAETARARGIKAI 60 Query: 66 IAGAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVAT--VGIDGA 123 IAGAGGAAHLPG++AA T +PV+GVP+ SK L G DSLLSIVQMP G+PVAT +G GA Sbjct: 61 IAGAGGAAHLPGMVAAKTTVPVLGVPVPSKYLRGEDSLLSIVQMPKGVPVATFAIGEAGA 120 Query: 124 KNAALLALEILSIKYPEIKEKLKKYREDMKRKVEEKSKKLEEL 166 NAAL A+ +L+ + PE+ +KL +R ++ V S +LE++ Sbjct: 121 ANAALFAVSMLANETPELAQKLADFRAKQEQAV--LSMELEQI 161 >pir||G81083 phosphoribosylaminoimidazole carboxylase, catalytic chain NMB1439 [imported] - Neisseria meningitidis (group B strain MD58) >gi|7226680|gb|AAF41800.1| (AE002493) phosphoribosylaminoimidazole carboxylase, catalytic subunit [Neisseria meningitidis MC58] Length = 161 Score = 177 bits (445), Expect = 6e-44 Identities = 89/153 (58%), Positives = 119/153 (77%), Gaps = 2/153 (1%) Query: 6 MPKVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVI 65 M ++GIIMGS+SD PVM++AA+ LE+F V+YE +V+SAHRTP+ + +YA TA RGI+ I Sbjct: 1 MIQIGIIMGSNSDWPVMRQAAQFLEEFGVEYEARVVSAHRTPDLMFQYAETARARGIKAI 60 Query: 66 IAGAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVAT--VGIDGA 123 IAGAGGAAHLPG++AA T +PV+GVP+ SK L G DSLLSIVQMP G+PVAT +G GA Sbjct: 61 IAGAGGAAHLPGMVAAKTTVPVLGVPVPSKYLRGEDSLLSIVQMPKGVPVATFAIGEAGA 120 Query: 124 KNAALLALEILSIKYPEIKEKLKKYREDMKRKV 156 NAAL A+ +L+ + PE+ +KL +R ++ V Sbjct: 121 ANAALFAVSMLANETPELAQKLADFRAKQEQAV 153 >pir||C82370 phosphoribosylaminoimidazole carboxylase, catalytic chain VC0052 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9654446|gb|AAF93230.1| (AE004096) phosphoribosylaminoimidazole carboxylase, catalytic subunit [Vibrio cholerae] Length = 161 Score = 176 bits (442), Expect = 1e-43 Identities = 91/159 (57%), Positives = 116/159 (72%), Gaps = 2/159 (1%) Query: 9 VGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVIIAG 68 VGIIMGS SD P MK AA++L+ F V YE KV+SAHRTP L +YA +A+ERG++VIIAG Sbjct: 3 VGIIMGSKSDWPTMKHAAEMLDQFGVAYETKVVSAHRTPHLLADYASSAKERGLQVIIAG 62 Query: 69 AGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVAT--VGIDGAKNA 126 AGGAAHLPG+ AA T +PV+GVP++S+AL+GLDSL SIVQMP GI V T +G GA NA Sbjct: 63 AGGAAHLPGMTAAFTSLPVLGVPVQSRALSGLDSLYSIVQMPKGIAVGTLAIGEAGAANA 122 Query: 127 ALLALEILSIKYPEIKEKLKKYREDMKRKVEEKSKKLEE 165 LLA +I+ I PE+ K++ +R + V + EE Sbjct: 123 GLLAAQIIGIHNPEVMSKVEAFRAKQTQSVLDNPNPAEE 161 >sp|P46702|PUR6_MYCLE PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE CATALYTIC SUBUNIT (AIR CARBOXYLASE) (AIRC) >gi|466867|gb|AAA85943.1| (U00012) pur6; B1308_f3_98 [Mycobacterium leprae] Length = 171 Score = 171 bits (430), Expect = 3e-42 Identities = 85/158 (53%), Positives = 116/158 (72%) Query: 7 PKVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVII 66 P+VG+IMGSDSD VM++AA L +F++ E++V+SAHRTP + +YAR A +R I VII Sbjct: 5 PRVGVIMGSDSDWSVMQDAAHALAEFDIPIEVRVVSAHRTPAEMFDYARNAVDRSIAVII 64 Query: 67 AGAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVATVGIDGAKNA 126 AGAGGAAHLPG++A+ T +PVIGVP+ L+GLDSLLSIVQMP G+PVATV I GA+NA Sbjct: 65 AGAGGAAHLPGMVASATPLPVIGVPVPLARLDGLDSLLSIVQMPAGVPVATVSIGGARNA 124 Query: 127 ALLALEILSIKYPEIKEKLKKYREDMKRKVEEKSKKLE 164 LLA+ IL +++ +L +++ + V K L+ Sbjct: 125 GLLAVRILGSSDLQLRAQLVAFQDRLADTVRAKDADLQ 162 >pir||C82528 phosphoribosylaminoimidazole carboxylase, catalytic subunit XF2672 [imported] - Xylella fastidiosa (strain 9a5c) >gi|9107908|gb|AAF85469.1|AE004073_4 (AE004073) phosphoribosylaminoimidazole carboxylase, catalytic subunit [Xylella fastidiosa] Length = 167 Score = 168 bits (422), Expect = 3e-41 Identities = 88/144 (61%), Positives = 110/144 (76%), Gaps = 2/144 (1%) Query: 9 VGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVIIAG 68 VGI+MGS SD M+ AA+ L+ V YE+KV+SAHRTP++L YA AE RG+ IIAG Sbjct: 10 VGIVMGSSSDWGAMQHAAQKLDALGVAYEVKVVSAHRTPDKLFAYAEQAEGRGLRAIIAG 69 Query: 69 AGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVAT--VGIDGAKNA 126 AGGAAHLPG+LAA TM+PV+GVP++SKALNGLDSLLSIVQMP GIPVAT +G GA NA Sbjct: 70 AGGAAHLPGMLAAKTMVPVLGVPMQSKALNGLDSLLSIVQMPAGIPVATFAIGEAGAVNA 129 Query: 127 ALLALEILSIKYPEIKEKLKKYRE 150 AL A +L + P ++ L ++R+ Sbjct: 130 ALFAAALLVPENPAMRRMLTEFRQ 153 >pir||H82967 phosphoribosylaminoimidazole carboxylase, catalytic subunit PA5426 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9951754|gb|AAG08811.1|AE004955_5 (AE004955) phosphoribosylaminoimidazole carboxylase, catalytic subunit [Pseudomonas aeruginosa] Length = 163 Score = 167 bits (419), Expect = 6e-41 Identities = 85/150 (56%), Positives = 110/150 (72%), Gaps = 2/150 (1%) Query: 9 VGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVIIAG 68 VG+IMGS SD + A +L+ + YE+KV+SAHRTP+ L +YA AE RG+EVIIAG Sbjct: 5 VGVIMGSKSDWSTLSHTADMLDKLGIPYEVKVVSAHRTPDLLFQYAEEAEGRGLEVIIAG 64 Query: 69 AGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVAT--VGIDGAKNA 126 AGGAAHLPG+ AA T +PV+GVP++S L+G+DSLLSIVQMP G+PVAT +G GA NA Sbjct: 65 AGGAAHLPGMCAAKTHLPVLGVPVQSSMLSGVDSLLSIVQMPAGVPVATLAIGKAGAVNA 124 Query: 127 ALLALEILSIKYPEIKEKLKKYREDMKRKV 156 ALL+ IL K+P+ E LK++R + V Sbjct: 125 ALLSASILGAKHPQYHEALKQFRANQTETV 154 >sp|Q01930|PUR6_PICME PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE (AIR CARBOXYLASE) (AIRC) >gi|481666|pir||S39112 phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) - yeast (Pichia methanolica) >gi|457702|emb|CAA54041.1| (X76529) 5-aminoimidazole ribonucleotide-carboxilase [Pichia methanolica] Length = 543 Score = 167 bits (418), Expect = 8e-41 Identities = 82/133 (61%), Positives = 104/133 (77%) Query: 7 PKVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVII 66 P VG+IMGSDSDLPVM +L+ F V +E+ ++SAHRTP+R+ +YA A +RG++ II Sbjct: 402 PLVGVIMGSDSDLPVMSLGCNILKQFNVPFEVTIVSAHRTPQRMAKYAIDAPKRGLKCII 461 Query: 67 AGAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVATVGIDGAKNA 126 AGAGGAAHLPG++AA+T +PVIGVP+K L+G+DSL SIVQMP GIPVATV I+ A NA Sbjct: 462 AGAGGAAHLPGMVAAMTPLPVIGVPVKGSTLDGVDSLHSIVQMPRGIPVATVAINNATNA 521 Query: 127 ALLALEILSIKYP 139 ALLA+ IL P Sbjct: 522 ALLAITILGAGDP 534 >sp|P72157|PUR6_PSEAE PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE CATALYTIC SUBUNIT (AIR CARBOXYLASE) (AIRC) >gi|1621600|gb|AAB17257.1| (U58364) PurE [Pseudomonas aeruginosa] Length = 163 Score = 166 bits (416), Expect = 1e-40 Identities = 85/159 (53%), Positives = 112/159 (69%), Gaps = 2/159 (1%) Query: 9 VGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVIIAG 68 VG+IMGS SD + A +L+ + YE+KV+SAHRTP+ +YA AE RG+EVIIAG Sbjct: 5 VGVIMGSKSDWSTLSHTADMLDKLGIPYEVKVVSAHRTPDLFFQYAEEAEGRGLEVIIAG 64 Query: 69 AGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVAT--VGIDGAKNA 126 AGGAAHLPG+ AA T +PV+GVP++S L+G+DSLLSIVQMP G+PVAT +G GA NA Sbjct: 65 AGGAAHLPGMCAAKTHLPVLGVPVQSSMLSGVDSLLSIVQMPAGVPVATLAIGKAGAVNA 124 Query: 127 ALLALEILSIKYPEIKEKLKKYREDMKRKVEEKSKKLEE 165 ALL+ IL K+P+ E LK++R + V + +E Sbjct: 125 ALLSASILGAKHPQYHEALKQFRANQTETVLDNPDPRDE 163 >sp|Q58033|PUR6_METJA PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE CATALYTIC SUBUNIT (AIR CARBOXYLASE) (AIRC) >gi|2129196|pir||H64376 phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) - Methanococcus jannaschii >gi|1591327|gb|AAB98611.1| (U67510) phosphoribosylaminoimidazole carboxylase, (purE) [Methanococcus jannaschii] Length = 157 Score = 164 bits (410), Expect = 7e-40 Identities = 87/156 (55%), Positives = 120/156 (76%), Gaps = 4/156 (2%) Query: 11 IIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVIIAGAG 70 IIMGS+SDL + ++A +L++F V++E++V SAHRTPE + E + ++ +V IA AG Sbjct: 4 IIMGSESDLKIAEKAVNILKEFGVEFEVRVASAHRTPELVEEIVKNSKA---DVFIAIAG 60 Query: 71 GAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVATVGIDGAKNAALLA 130 AAHLPGV+A+LT PVI VP+ +K L+GLD+LLS VQMPPGIPVATVGID +NAA+LA Sbjct: 61 LAAHLPGVVASLTTKPVIAVPVDAK-LDGLDALLSSVQMPPGIPVATVGIDRGENAAILA 119 Query: 131 LEILSIKYPEIKEKLKKYREDMKRKVEEKSKKLEEL 166 LEIL++K I +KL +YRE MK+KV +K++E+ Sbjct: 120 LEILALKDENIAKKLIEYREKMKKKVYASDEKVKEM 155 >pir||S54434 phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) catalytic chain - Haemophilus influenzae (strain AM30) (fragment) >gi|535174|emb|CAA83909.1| (Z33502) PurE [Haemophilus influenzae] Length = 161 Score = 162 bits (405), Expect = 3e-39 Identities = 79/151 (52%), Positives = 112/151 (73%), Gaps = 2/151 (1%) Query: 8 KVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVIIA 67 ++ ++MGS SD M+EA ++L++ V Y ++V+SAHRTP++L E+A A++ G +VIIA Sbjct: 6 QIAVVMGSKSDWATMQEATQILDELNVPYHVEVVSAHRTPDKLFEFAENAQKNGYKVIIA 65 Query: 68 GAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVAT--VGIDGAKN 125 GAGGAAHLPG++AA T++PV+GVP+KS L+G+DSL SIVQMP GIPV T +G GA N Sbjct: 66 GAGGAAHLPGMIAAKTLVPVLGVPVKSSMLSGVDSLYSIVQMPKGIPVGTLAIGPAGAAN 125 Query: 126 AALLALEILSIKYPEIKEKLKKYREDMKRKV 156 A LLA +IL+ E+ +L+ +RE R V Sbjct: 126 AGLLAAQILAGWDAELLSRLQSFRESQTRAV 156 >sp|P09028|PUR6_ECOLI PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE CATALYTIC SUBUNIT (AIR CARBOXYLASE) (AIRC) >gi|67997|pir||DEECPE phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) catalytic chain - Escherichia coli >gi|42588|emb|CAA31420.1| (X12982) purE gene product (catalytic subunit) (AA 1- 169) [Escherichia coli] >gi|147412|gb|AAA24449.1| (M19657) 5'-phosphoribosyl-5-amino-4-imidazole carboxylase I (purE, EC 4.1.1.21) [Escherichia coli] >gi|1773204|gb|AAB40276.1| (U82664) phosphoribosylaminoimidazole carboxylase [Escherichia coli] >gi|1786734|gb|AAC73625.1| (AE000158) phosphoribosylaminoimidazole carboxylase = AIR carboxylase, catalytic subunit [Escherichia coli K12] Length = 169 Score = 158 bits (396), Expect = 3e-38 Identities = 81/153 (52%), Positives = 113/153 (72%), Gaps = 2/153 (1%) Query: 8 KVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVIIA 67 +V I+MGS SD M+ AA++ E V + ++V+SAHRTP++L +A +AEE G +VIIA Sbjct: 9 RVAIVMGSKSDWATMQFAAEIFEILNVPHHVEVVSAHRTPDKLFSFAESAEENGYQVIIA 68 Query: 68 GAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVAT--VGIDGAKN 125 GAGGAAHLPG++AA T++PV+GVP++S AL+G+DSL SIVQMP GIPV T +G GA N Sbjct: 69 GAGGAAHLPGMIAAKTLVPVLGVPVQSAALSGVDSLYSIVQMPRGIPVGTLAIGKAGAAN 128 Query: 126 AALLALEILSIKYPEIKEKLKKYREDMKRKVEE 158 AALLA +IL+ E+ ++L +R+ +V E Sbjct: 129 AALLAAQILATHDKELHQRLNDWRKAQTDEVLE 161 >pir||H75568 phosphoribosylaminoimidazole carboxylase, catalytic subunit - Deinococcus radiodurans (strain R1) >gi|6457682|gb|AAF09615.1|AE001866_2 (AE001866) phosphoribosylaminoimidazole carboxylase, catalytic subunit [Deinococcus radiodurans] Length = 177 Score = 158 bits (395), Expect = 4e-38 Identities = 80/145 (55%), Positives = 106/145 (72%), Gaps = 2/145 (1%) Query: 7 PKVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVII 66 P+VG++MGS SD M+ A +L E+ YE++V+SAHRTP L YA AE G+ II Sbjct: 11 PRVGVVMGSRSDSETMQGALDLLSQLEIPYEVRVLSAHRTPGLLSTYAARAERLGLACII 70 Query: 67 AGAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVAT--VGIDGAK 124 AGAGGAAHLPG+LAA T +PV+GVP++S+AL+G DSLLSIVQMP G+PVAT +G GAK Sbjct: 71 AGAGGAAHLPGMLAAFTRVPVLGVPVQSRALSGQDSLLSIVQMPAGVPVATFAIGQAGAK 130 Query: 125 NAALLALEILSIKYPEIKEKLKKYR 149 NAAL A +L+ ++ +L+ +R Sbjct: 131 NAALFAAALLATTDAGVRTRLEAFR 155 >sp|P43849|PUR6_HAEIN PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE CATALYTIC SUBUNIT (AIR CARBOXYLASE) (AIRC) >gi|1075150|pir||G64132 phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) catalytic chain - Haemophilus influenzae (strain Rd KW20) >gi|1574461|gb|AAC23263.1| (U32835) phosphoribosylaminoimidazole carboxylase, catalytic subunit (purE) [Haemophilus influenzae Rd] Length = 164 Score = 157 bits (392), Expect = 9e-38 Identities = 77/151 (50%), Positives = 111/151 (72%), Gaps = 2/151 (1%) Query: 8 KVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVIIA 67 ++ ++MGS SD M+EA ++L++ V Y ++V+SAHRTP++L E+A A++ G +VIIA Sbjct: 6 QIAVVMGSKSDWATMQEATQILDELNVPYHVEVVSAHRTPDKLFEFAENAQKNGYKVIIA 65 Query: 68 GAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVAT--VGIDGAKN 125 GAGGAAHLPG++AA T++PV+GVP+KS L+G+DSL SIVQMP GIPV T +G GA N Sbjct: 66 GAGGAAHLPGMIAAKTLVPVLGVPVKSSMLSGVDSLYSIVQMPKGIPVGTLAIGPAGAAN 125 Query: 126 AALLALEILSIKYPEIKEKLKKYREDMKRKV 156 A LLA +IL+ + +L+ +RE+ V Sbjct: 126 AGLLAAQILAGWDDALFTRLQAFRENQTNMV 156 >pir||A81341 phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) catalytic chain Cj0702 [imported] - Campylobacter jejuni (strain NCTC 11168) >gi|6968159|emb|CAB72976.1| (AL139076) phosphoribosylaminoimidazole carboxylase catalytic subunit [Campylobacter jejuni] Length = 164 Score = 152 bits (379), Expect = 3e-36 Identities = 83/160 (51%), Positives = 109/160 (67%), Gaps = 2/160 (1%) Query: 9 VGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVIIAG 68 V I+MGS SD MKEAAK LE F V YE+ + SAHR+P+R EY AEE+G++V IA Sbjct: 4 VSILMGSKSDYETMKEAAKTLESFGVKYELIISSAHRSPKRTKEYIANAEEKGVKVFIAA 63 Query: 69 AGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVAT--VGIDGAKNA 126 AG AAHL G +AA T PV+GVP+ L +DSL S VQMP GIPV T +G GA NA Sbjct: 64 AGMAAHLAGAVAAYTTKPVLGVPMSGSNLASMDSLFSTVQMPSGIPVGTLAIGKAGAINA 123 Query: 127 ALLALEILSIKYPEIKEKLKKYREDMKRKVEEKSKKLEEL 166 A LA++IL+I ++ +KLK+ R + ++K+ SK++E L Sbjct: 124 AYLAMQILAIYDVDLAQKLKEDRLEKEKKLVSDSKEVEVL 163 >pdb|1QCZ|A Chain A, Crystal Structure Of E. Coli Pure, An Unusual Mutase That Catalyzes The Conversion Of N5-Carboxyaminoimidazole Ribonucleotide (N5-Cair) To 4-Carboxyaminoimidazole Ribonucleotide (Cair) In The Purine Biosynthetic Pathway Length = 169 Score = 150 bits (376), Expect = 7e-36 Identities = 78/153 (50%), Positives = 109/153 (70%), Gaps = 2/153 (1%) Query: 8 KVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVIIA 67 +V I+ GS SD + AA++ E V + ++V+SAHRTP++L +A +AEE G +VIIA Sbjct: 9 RVAIVXGSKSDWATXQFAAEIFEILNVPHHVEVVSAHRTPDKLFSFAESAEENGYQVIIA 68 Query: 68 GAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVAT--VGIDGAKN 125 GAGGAAHLPG +AA T++PV+GVP++S AL+G+DSL SIVQ P GIPV T +G GA N Sbjct: 69 GAGGAAHLPGXIAAKTLVPVLGVPVQSAALSGVDSLYSIVQXPRGIPVGTLAIGKAGAAN 128 Query: 126 AALLALEILSIKYPEIKEKLKKYREDMKRKVEE 158 AALLA +IL+ E+ ++L +R+ +V E Sbjct: 129 AALLAAQILATHDKELHQRLNDWRKAQTDEVLE 161 >pdb|1D7A|A Chain A, Crystal Structure Of E. Coli Pure-Mononucleotide Complex. >gi|6730255|pdb|1D7A|B Chain B, Crystal Structure Of E. Coli Pure-Mononucleotide Complex. >gi|6730256|pdb|1D7A|C Chain C, Crystal Structure Of E. Coli Pure-Mononucleotide Complex. >gi|6730257|pdb|1D7A|D Chain D, Crystal Structure Of E. Coli Pure-Mononucleotide Complex. >gi|6730258|pdb|1D7A|L Chain L, Crystal Structure Of E. Coli Pure-Mononucleotide Complex. >gi|6730259|pdb|1D7A|M Chain M, Crystal Structure Of E. Coli Pure-Mononucleotide Complex. >gi|6730260|pdb|1D7A|N Chain N, Crystal Structure Of E. Coli Pure-Mononucleotide Complex. >gi|6730261|pdb|1D7A|O Chain O, Crystal Structure Of E. Coli Pure-Mononucleotide Complex Length = 161 Score = 150 bits (376), Expect = 7e-36 Identities = 78/153 (50%), Positives = 109/153 (70%), Gaps = 2/153 (1%) Query: 8 KVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVIIA 67 +V I+ GS SD + AA++ E V + ++V+SAHRTP++L +A +AEE G +VIIA Sbjct: 3 RVAIVXGSKSDWATXQFAAEIFEILNVPHHVEVVSAHRTPDKLFSFAESAEENGYQVIIA 62 Query: 68 GAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVAT--VGIDGAKN 125 GAGGAAHLPG +AA T++PV+GVP++S AL+G+DSL SIVQ P GIPV T +G GA N Sbjct: 63 GAGGAAHLPGXIAAKTLVPVLGVPVQSAALSGVDSLYSIVQXPRGIPVGTLAIGKAGAAN 122 Query: 126 AALLALEILSIKYPEIKEKLKKYREDMKRKVEE 158 AALLA +IL+ E+ ++L +R+ +V E Sbjct: 123 AALLAAQILATHDKELHQRLNDWRKAQTDEVLE 155 >sp|P52558|PUR6_BRUME PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE CATALYTIC SUBUNIT (AIR CARBOXYLASE) (AIRC) >gi|600729|gb|AAA57002.1| (U10241) 5'-phosphoribosyl-5-amino-4-imidazole carboxylase [Brucella melitensis] Length = 161 Score = 144 bits (360), Expect = 5e-34 Identities = 78/153 (50%), Positives = 105/153 (67%), Gaps = 3/153 (1%) Query: 9 VGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVIIAG 68 V IIMGS SD M AA LE + ++ +++SAHRTP+RL +A+ A+ G +VIIAG Sbjct: 5 VAIIMGSQSDWETMHHAADTLEALGISFDARIVSAHRTPDRLVAFAKGAKREGFKVIIAG 64 Query: 69 AGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVAT--VGIDGAKNA 126 AG AHLPG+ AA+T +PV GVP++SKAL+G DSLLSIVQMP GIPV T +G GA NA Sbjct: 65 AG-RAHLPGMAAAMTPLPVFGVPVQSKALSGQDSLLSIVQMPAGIPVGTLAIGRAGAVNA 123 Query: 127 ALLALEILSIKYPEIKEKLKKYREDMKRKVEEK 159 ALLA +L++ + +L ++R+ V E+ Sbjct: 124 ALLAAAVLALYDEALAARLDEWRKAQTESVAER 156 >sp|P22348|PUR6_METSM PROBABLE PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE (AIR CARBOXYLASE) (AIRC) >gi|322336|pir||S28656 phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) - Methanobrevibacter smithii >gi|44542|emb|CAA26422.1| (X02586) ORFA (aa 1-339) [Methanobrevibacter smithii] Length = 339 Score = 136 bits (339), Expect = 2e-31 Identities = 73/157 (46%), Positives = 105/157 (66%), Gaps = 1/157 (0%) Query: 7 PKVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVII 66 PKV II+GS SD+ + +++ K+LE E+ Y +K+ SAHRTP+ + E GI+V I Sbjct: 3 PKVMIILGSGSDIAIAEKSMKILEKLEIPYSLKIASAHRTPDLVRELVVQGTNAGIKVFI 62 Query: 67 AGAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVATVGIDGAKNA 126 AG AAHLPG +AA T PVIGVP+ K ++GLD+L S VQMP PVATVGID N Sbjct: 63 GIAGLAAHLPGAIAAYTHKPVIGVPVDVK-VSGLDALYSSVQMPYPSPVATVGIDRGDNG 121 Query: 127 ALLALEILSIKYPEIKEKLKKYREDMKRKVEEKSKKL 163 A+LA IL + EI++K+ + +E ++KV + ++++ Sbjct: 122 AILAARILGLYDEEIRKKVLESKEGYRQKVIKNNEEI 158 Score = 90.1 bits (220), Expect = 1e-17 Identities = 53/142 (37%), Positives = 86/142 (60%), Gaps = 4/142 (2%) Query: 8 KVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVIIA 67 +V II+G +DL K+ + L+ ++ ++M+VI R+ ++ Y T + ++ I Sbjct: 196 EVVIIVGRHTDLITGKKVSVTLDRLKIPHDMQVICPIRSGKKFRAYVNTM--KNAKIFIG 253 Query: 68 GAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVATVGIDGAKNAA 127 ++ + G L LT PVIGVP +++ G + LLS V MPPG+PVATVG++ +NAA Sbjct: 254 INSNSSQVSGGLVGLTEKPVIGVPCENEL--GNNYLLSTVNMPPGVPVATVGVNNGRNAA 311 Query: 128 LLALEILSIKYPEIKEKLKKYR 149 +L+ EILSI P + E L+K + Sbjct: 312 VLSGEILSINNPVLLELLEKLK 333 >sp|P41654|PUR6_METTH PROBABLE PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE (AIR CARBOXYLASE) (AIRC) >gi|44575|emb|CAA27010.1| (X03250) unidentified reading frame ORF-PurE(t) (aa 1-334) [Methanobacterium thermoautotrophicum] Length = 334 Score = 123 bits (307), Expect = 9e-28 Identities = 64/150 (42%), Positives = 98/150 (64%), Gaps = 1/150 (0%) Query: 7 PKVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVII 66 P+V I++GS SD + ++A ++ E+ + Y+++V SAHRT E++ A + G+EV I Sbjct: 3 PRVMILLGSASDFRIAEKAMEIFEELRIPYDLRVASAHRTHEKVKAIVSEAVKAGVEVFI 62 Query: 67 AGAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVATVGIDGAKNA 126 AG +AHLPG+++A T PVIGVP+ K L GLD+L + QMP PVATVG+D +NA Sbjct: 63 GIAGLSAHLPGMISANTHRPVIGVPVDVK-LGGLDALFACSQMPFPAPVATVGVDRGENA 121 Query: 127 ALLALEILSIKYPEIKEKLKKYREDMKRKV 156 A+LA +I+ I P ++E++ R +V Sbjct: 122 AILAAQIIGIGDPGVRERVADLRRGFYERV 151 Score = 113 bits (279), Expect = 2e-24 Identities = 61/143 (42%), Positives = 89/143 (61%), Gaps = 3/143 (2%) Query: 7 PKVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVII 66 P V +I GS SD+ + K+ LE + Y++ VIS R PER Y E +++ I Sbjct: 189 PMVSVIPGSYSDMKIAKKTTMFLERMGISYDLNVISPIRYPERFERYLEKMEN--VKLFI 246 Query: 67 AGAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVATVGIDGAKNA 126 A +G +AH+ G + AL+ PVIGVP K +NG DSLLS++ MPPG+PV TVG+ NA Sbjct: 247 AISGLSAHVTGAVVALSDRPVIGVPCPLK-MNGWDSLLSMINMPPGVPVGTVGVGNGGNA 305 Query: 127 ALLALEILSIKYPEIKEKLKKYR 149 A+LA E+L I +I+ ++K+ + Sbjct: 306 AILAAEMLGIYDEKIESRIKRIK 328 >pir||D69052 phosphoribosylaminoimidazole carboxylase - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622504|gb|AAB85870.1| (AE000902) phosphoribosylaminoimidazole carboxylase [Methanobacterium thermoautotrophicum] Length = 338 Score = 123 bits (307), Expect = 9e-28 Identities = 64/150 (42%), Positives = 98/150 (64%), Gaps = 1/150 (0%) Query: 7 PKVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVII 66 P+V I++GS SD + ++A ++ E+ + Y+++V SAHRT E++ A + G+EV I Sbjct: 7 PRVMILLGSASDFRIAEKAMEIFEELRIPYDLRVASAHRTHEKVKAIVSEAVKAGVEVFI 66 Query: 67 AGAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVATVGIDGAKNA 126 AG +AHLPG+++A T PVIGVP+ K L GLD+L + QMP PVATVG+D +NA Sbjct: 67 GIAGLSAHLPGMISANTHRPVIGVPVDVK-LGGLDALFACSQMPFPAPVATVGVDRGENA 125 Query: 127 ALLALEILSIKYPEIKEKLKKYREDMKRKV 156 A+LA +I+ I P ++E++ R +V Sbjct: 126 AILAAQIIGIGDPGVRERVADLRRGFYERV 155 Score = 113 bits (279), Expect = 2e-24 Identities = 61/143 (42%), Positives = 89/143 (61%), Gaps = 3/143 (2%) Query: 7 PKVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVII 66 P V +I GS SD+ + K+ LE + Y++ VIS R PER Y E +++ I Sbjct: 193 PMVSVIPGSYSDMKIAKKTTMFLERMGISYDLNVISPIRYPERFERYLEKMEN--VKLFI 250 Query: 67 AGAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVATVGIDGAKNA 126 A +G +AH+ G + AL+ PVIGVP K +NG DSLLS++ MPPG+PV TVG+ NA Sbjct: 251 AISGLSAHVTGAVVALSDRPVIGVPCPLK-MNGWDSLLSMINMPPGVPVGTVGVGNGGNA 309 Query: 127 ALLALEILSIKYPEIKEKLKKYR 149 A+LA E+L I +I+ ++K+ + Sbjct: 310 AILAAEMLGIYDEKIESRIKRIK 332 >gb|AAG19136.1| (AE005011) phosphoribosylaminoimidazole carboxylase catalytic subunit; PurE [Halobacterium sp. NRC-1] Length = 203 Score = 108 bits (268), Expect = 3e-23 Identities = 71/176 (40%), Positives = 97/176 (54%), Gaps = 21/176 (11%) Query: 7 PKVGIIMGSDSDLPVMKEAAKVLEDFE----VDY---------EMKVISAHRTPERLHEY 53 P VG+IMGSDSDL VM A L D DY E V+SAHRTP + Y Sbjct: 25 PDVGVIMGSDSDLDVMAGAHDALTDLGFTELTDYDDPPTGYTFESWVVSAHRTPTLMDAY 84 Query: 54 ARTAEERGIEVIIAGAGG-AAHLPGVLAALTM-IPVIGVPIKSKALNGLDSLLSIVQMPP 111 ARTA RG++VIIAGAGG +A LP + A+L IPV+GVP++ K S+ S++ MP Sbjct: 85 ARTAAARGLDVIIAGAGGKSADLPNMTASLAYPIPVVGVPVQEK------SVPSVIGMPT 138 Query: 112 GIPVATVGIDGAKNAALLALEILSIKYPEIKEKLKKYREDMKRKVEEKSKKLEELG 167 G P+ V + NA L A + L+ P + ++L+ + + V + S +L G Sbjct: 139 GAPITAVDAGKSYNAGLAAAQFLATDDPTLADRLRDLQAARQEGVADVSARLHSQG 194 >gi|11498870 phosphoribosylaminoimidazole carboxylase (purE) [Archaeoglobus fulgidus] >gi|3914487|sp|O28997|PUR6_ARCFU PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE CATALYTIC SUBUNIT (AIR CARBOXYLASE) (AIRC) >gi|7436517|pir||F69408 phosphoribosylaminoimidazole carboxylase (purE) homolog - Archaeoglobus fulgidus >gi|2649308|gb|AAB89973.1| (AE001016) phosphoribosylaminoimidazole carboxylase (purE) [Archaeoglobus fulgidus] Length = 180 Score = 88.5 bits (216), Expect = 4e-17 Identities = 56/156 (35%), Positives = 91/156 (57%), Gaps = 4/156 (2%) Query: 8 KVGIIMGSDSDLPVMKEAAKVLEDFEVDYEMKVISAHRTPERLHEYARTAEERGIEVIIA 67 K IIMGS SDL K+ A L DF +D M++ SAH+TPE++ E + E+ + V + Sbjct: 28 KAVIIMGSKSDLDYSKKIASKLADFGIDAVMRIASAHKTPEKVLEIIKEYEKEDV-VFVT 86 Query: 68 GAGGAAHLPGVLAALTMIPVIGVPIKSKALNGLDSLLSIVQMPPGIPVATVGIDGAKNAA 127 AG + L G + A T PVI P S G D + S ++MP G VA + + A+NAA Sbjct: 87 VAGRSNALSGFVDANTSKPVIASPPYSDKFGGAD-IFSSIRMPSG--VAPMLVLEAENAA 143 Query: 128 LLALEILSIKYPEIKEKLKKYREDMKRKVEEKSKKL 163 L +I ++K ++EK+ +++E+ +R++ + ++L Sbjct: 144 LAVAKIFALKDEGVREKVVQFQENKRREIYKADEEL 179 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.315 0.136 0.375 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 63622153 Number of Sequences: 2977 Number of extensions: 2532408 Number of successful extensions: 12588 Number of sequences better than 1.0e-10: 50 Number of HSP's better than 0.0 without gapping: 48 Number of HSP's successfully gapped in prelim test: 2 Number of HSP's that attempted gapping in prelim test: 12505 Number of HSP's gapped (non-prelim): 53 length of query: 174 length of database: 189,106,746 effective HSP length: 57 effective length of query: 117 effective length of database: 154,992,987 effective search space: 18134179479 effective search space used: 18134179479 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 42 (22.0 bits) S2: 162 (67.5 bits)