BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB1101 (PAB1101) DE:Transport protein
         (746 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||A75018 transport protein PAB1101 - Pyrococcus abyssi (strai...  1435  0.0
pir||H71453 hypothetical protein PH0287 - Pyrococcus horikoshii ...  1267  0.0
sp|Q58957|YF62_METJA PUTATIVE MEMBRANE PROTEIN MJ1562 >gi|212893...   255  2e-66
gi|11498828 conserved hypothetical protein [Archaeoglobus fulgid...   231  3e-59
gi|11498071 conserved hypothetical protein [Archaeoglobus fulgid...   203  5e-51
gb|AAG19780.1| (AE005063) Vng1476c [Halobacterium sp. NRC-1]          173  5e-42
pir||D70131 conserved hypothetical integral membrane protein BB0...   145  1e-33
pir||E72272 conserved hypothetical protein - Thermotoga maritima...   141  3e-32
sp|O54101|MMLB_STRCO PUTATIVE MEMBRANE PROTEIN SC10A5.10C >gi|74...   115  2e-24
pir||D72329 hypothetical protein - Thermotoga maritima (strain M...   102  1e-20
gb|AAD44231.1|AF143772_37 (AF143772) TmtpB [Mycobacterium avium]      101  3e-20
sp|O53784|MML5_MYCTU PUTATIVE MEMBRANE PROTEIN MMPL5 >gi|7478343...   101  4e-20
emb|CAB90894.1| (AL355753) putative integral membrane protein. [...    97  6e-19
pir||B81282 probable integral membrane protein Cj1373 [imported]...    94  4e-18
emb|CAB89762.1| (AL354616) putative integral membrane protein. [...    94  5e-18
emb|CAB89749.1| (AL354616) putative membrane protein [Streptomyc...    92  2e-17
dbj|BAB04439.1| (AP001509) unknown conserved protein in others [...    89  1e-16
emb|CAB59662.1| (AL132674) putative membrane transport protein [...    87  5e-16
sp|P54881|MML4_MYCLE PUTATIVE MEMBRANE PROTEIN MMPL4 >gi|699243|...    87  5e-16
sp|O50439|MMLA_MYCTU PUTATIVE MEMBRANE PROTEIN MMPL10 >gi|747902...    86  1e-15
sp|Q11171|MML2_MYCTU PUTATIVE MEMBRANE PROTEIN MMPL2 >gi|7478399...    85  3e-15
sp|O53735|MML4_MYCTU PUTATIVE MEMBRANE PROTEIN MMPL4 >gi|7478403...    85  3e-15
sp|O07800|MML8_MYCTU PUTATIVE MEMBRANE PROTEIN MMPL8 >gi|7478406...    83  1e-14
emb|CAB56653.1| (AL121596) putative membrane transport protein [...    82  2e-14
gb|AAF97217.1|AF271635_1 (AF271635) putative transport membrane ...    82  3e-14
pir||E71280 probable antibiotic transport protein - syphilis spi...    80  7e-14
sp|Q50585|MMLC_MYCTU PUTATIVE MEMBRANE PROTEIN MMPL12 >gi|747839...    79  2e-13
sp|Q49619|MMLA_MYCLE PUTATIVE MEMBRANE PROTEIN MMPL10 >gi|214597...    78  3e-13
pir||A75560 conserved hypothetical protein - Deinococcus radiodu...    76  1e-12
sp|Q53902|MMLA_STRCO PUTATIVE MEMBRANE PROTEIN ACTII-3 >gi|80715...    75  2e-12
pir||T23399 hypothetical protein K07C10.1 - Caenorhabditis elega...    75  4e-12
sp|P96706|YDGH_BACSU PUTATIVE MEMBRANE PROTEIN YDGH >gi|7475936|...    74  7e-12
emb|CAB86119.1| (AL163003) putative integral membrane protein [S...    73  9e-12
sp|P95211|MML1_MYCTU PUTATIVE MEMBRANE PROTEIN MMPL1 >gi|7478394...    72  3e-11

>pir||A75018 transport protein PAB1101 - Pyrococcus abyssi (strain Orsay)
           >gi|5459097|emb|CAB50583.1| (AJ248288) Transport protein
           [Pyrococcus abyssi]
           Length = 746
           
 Score = 1435 bits (3673), Expect = 0.0
 Identities = 746/746 (100%), Positives = 746/746 (100%)

Query: 1   MLRKIARVIVIYRHSLAVVTMFLLILSAYGITQLRFETDLSKQLPEDLEAVKSYFTLQNE 60
           MLRKIARVIVIYRHSLAVVTMFLLILSAYGITQLRFETDLSKQLPEDLEAVKSYFTLQNE
Sbjct: 1   MLRKIARVIVIYRHSLAVVTMFLLILSAYGITQLRFETDLSKQLPEDLEAVKSYFTLQNE 60

Query: 61  FGGSGSALIYVKIKNNDNVVDIRDPKIIEAMYSLEQRLREKEYVTDTFSIADLMVQILGR 120
           FGGSGSALIYVKIKNNDNVVDIRDPKIIEAMYSLEQRLREKEYVTDTFSIADLMVQILGR
Sbjct: 61  FGGSGSALIYVKIKNNDNVVDIRDPKIIEAMYSLEQRLREKEYVTDTFSIADLMVQILGR 120

Query: 121 LPKNMDEVKFVLNMLPPEARNGLISGDYSSTIIIVNLNREKNQKALVRVYNDIEREIERT 180
           LPKNMDEVKFVLNMLPPEARNGLISGDYSSTIIIVNLNREKNQKALVRVYNDIEREIERT
Sbjct: 121 LPKNMDEVKFVLNMLPPEARNGLISGDYSSTIIIVNLNREKNQKALVRVYNDIEREIERT 180

Query: 181 NFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPLVPL 240
           NFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPLVPL
Sbjct: 181 NFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPLVPL 240

Query: 241 IFGVVMTLGFMGLLGIPLDIATTTVGAMIIGMGIDYGVHVTNRYYEERGKGKSLEEAAEE 300
           IFGVVMTLGFMGLLGIPLDIATTTVGAMIIGMGIDYGVHVTNRYYEERGKGKSLEEAAEE
Sbjct: 241 IFGVVMTLGFMGLLGIPLDIATTTVGAMIIGMGIDYGVHVTNRYYEERGKGKSLEEAAEE 300

Query: 301 AIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVTPALAILE 360
           AIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVTPALAILE
Sbjct: 301 AIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVTPALAILE 360

Query: 361 EEFREKVMKKKEIIAIGGGKSKISFIFSMLGKAIKRSPWTALLIALIISGVSLYGASKIT 420
           EEFREKVMKKKEIIAIGGGKSKISFIFSMLGKAIKRSPWTALLIALIISGVSLYGASKIT
Sbjct: 361 EEFREKVMKKKEIIAIGGGKSKISFIFSMLGKAIKRSPWTALLIALIISGVSLYGASKIT 420

Query: 421 TEVRLEKMIPTDLPEIQALSDIRSEFGGQDEVTILIKADDVRDPTLVRDILRFEREIKAD 480
           TEVRLEKMIPTDLPEIQALSDIRSEFGGQDEVTILIKADDVRDPTLVRDILRFEREIKAD
Sbjct: 421 TEVRLEKMIPTDLPEIQALSDIRSEFGGQDEVTILIKADDVRDPTLVRDILRFEREIKAD 480

Query: 481 SYINNVFETQSIADVVIQKYGYIPQDKEKISEAIEGSSLVSSDYSMTIIKLKGNFMGVTQ 540
           SYINNVFETQSIADVVIQKYGYIPQDKEKISEAIEGSSLVSSDYSMTIIKLKGNFMGVTQ
Sbjct: 481 SYINNVFETQSIADVVIQKYGYIPQDKEKISEAIEGSSLVSSDYSMTIIKLKGNFMGVTQ 540

Query: 541 SEFNRIMEYFERAIQRADFPPGVKVELAGESYLNYVLNDLVNEELGKISTIGTLIVVMVV 600
           SEFNRIMEYFERAIQRADFPPGVKVELAGESYLNYVLNDLVNEELGKISTIGTLIVVMVV
Sbjct: 541 SEFNRIMEYFERAIQRADFPPGVKVELAGESYLNYVLNDLVNEELGKISTIGTLIVVMVV 600

Query: 601 FAIFRRPTVSIAMIMPMFLGALWTIGYMGLAGIPFSQTLAGVVSMIVGLGVDYGMHITHR 660
           FAIFRRPTVSIAMIMPMFLGALWTIGYMGLAGIPFSQTLAGVVSMIVGLGVDYGMHITHR
Sbjct: 601 FAIFRRPTVSIAMIMPMFLGALWTIGYMGLAGIPFSQTLAGVVSMIVGLGVDYGMHITHR 660

Query: 661 FLEELNEGNKTPIITALESVGPGIFVGALTTAGGFLALLSAQLTAIHDFGRVLAVGIFAS 720
           FLEELNEGNKTPIITALESVGPGIFVGALTTAGGFLALLSAQLTAIHDFGRVLAVGIFAS
Sbjct: 661 FLEELNEGNKTPIITALESVGPGIFVGALTTAGGFLALLSAQLTAIHDFGRVLAVGIFAS 720

Query: 721 MFAAYLVTPAILQLEFGRKISKEVRE 746
           MFAAYLVTPAILQLEFGRKISKEVRE
Sbjct: 721 MFAAYLVTPAILQLEFGRKISKEVRE 746


>pir||H71453 hypothetical protein PH0287 - Pyrococcus horikoshii
           >gi|3256676|dbj|BAA29359.1| (AP000001) 787aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 787
           
 Score = 1267 bits (3242), Expect = 0.0
 Identities = 635/747 (85%), Positives = 712/747 (95%), Gaps = 2/747 (0%)

Query: 1   MLRKIARVIVIYRHSLAVVTMFLLILSAYGITQLRFETDLSKQLPEDLEAVKSYFTLQNE 60
           MLRKIAR+IV+YRHSLAV+T+FLLILS YGIT+L+FE+DLSKQLPEDLEAVK+YFTLQNE
Sbjct: 42  MLRKIARIIVVYRHSLAVITIFLLILSGYGITKLKFESDLSKQLPEDLEAVKNYFTLQNE 101

Query: 61  FGGSGSALIYVKIKNNDNVVDIRDPKIIEAMYSLEQRLREKEYVTDTFSIADLMVQILGR 120
           FGGSGSALIYVKIK+ D V DIRDP +I+AMYSLEQRL++KEYVTDTFSIADL VQILGR
Sbjct: 102 FGGSGSALIYVKIKSPDKVADIRDPTVIKAMYSLEQRLKDKEYVTDTFSIADLAVQILGR 161

Query: 121 LPKNMDEVKFVLNMLPPEARNGLISGDYSSTIIIVNLNREKNQKALVRVYNDIEREIERT 180
           LP N++EVKFVLNMLP +ARNGL+S DYSSTIIIV+LNREKNQ+ALVRVYN+I+ EIE++
Sbjct: 162 LPNNIEEVKFVLNMLPEDARNGLVSRDYSSTIIIVSLNREKNQRALVRVYNEIKNEIEKS 221

Query: 181 NFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPLVPL 240
           NFP+GVEVVLTGDLGITYKILEMLQNDMNRTMA++GIIV+++LLYFYKSPIRMLVPL+PL
Sbjct: 222 NFPEGVEVVLTGDLGITYKILEMLQNDMNRTMAVAGIIVIILLLYFYKSPIRMLVPLIPL 281

Query: 241 IFGVVMTLGFMGLLGIPLDIATTTVGAMIIGMGIDYGVHVTNRYYEERGKGKSLEEAAEE 300
           IFGV MTLGFMGLLGIPLDIAT+TVGAMIIGMGIDYGVHVTNRYYEER KG+S EEAAEE
Sbjct: 282 IFGVTMTLGFMGLLGIPLDIATSTVGAMIIGMGIDYGVHVTNRYYEERNKGRSPEEAAEE 341

Query: 301 AIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVTPALAILE 360
           AI+ETGKALLGAALTTIAGFLALS+SILPSLKRLS+SLVMGLGLAA+NAVIVTPALAILE
Sbjct: 342 AISETGKALLGAALTTIAGFLALSLSILPSLKRLSISLVMGLGLAAVNAVIVTPALAILE 401

Query: 361 EEFREKVMKKK-EIIAIGGGKSKISFIFSMLGKAIKRSPWTALLIALIISGVSLYGASKI 419
           EEFR K++ KK EII+IGG + K+ FIFS LG  IKRSPW ALLIA++ISGVSLYGA+KI
Sbjct: 402 EEFRTKILGKKGEIISIGGEEGKLGFIFSRLGLFIKRSPWLALLIAVMISGVSLYGATKI 461

Query: 420 TTEVRLEKMIPTDLPEIQALSDIRSEFGGQDEVTILIKADDVRDPTLVRDILRFEREIKA 479
           TTEVRLEKMIP D+PEIQAL+DIRSEFGGQDE+TILIKADDVRDP +VR ILRFERE+KA
Sbjct: 462 TTEVRLEKMIPMDMPEIQALTDIRSEFGGQDEITILIKADDVRDPEIVRSILRFEREVKA 521

Query: 480 DSYINNVFETQSIADVVIQKYGYIPQDKEKISEAIEGSSLVSSDYSMTIIKLKGNFMGVT 539
           DSYINNVFE++SIADVVI+KYGYIP+DKEKI++A+EGSSLVSSDYS+TI+KLKGNFMGVT
Sbjct: 522 DSYINNVFESESIADVVIEKYGYIPEDKEKIAKALEGSSLVSSDYSLTIVKLKGNFMGVT 581

Query: 540 QSEFNRIMEYFERAIQRADFPPGVKVELAGESYLNYVLNDLVNEELGKISTIGTLIVVMV 599
           Q +FN+IMEYFE  ++RA+FPPGVK ELAGESYLNYVL++LVNEELGKISTIGT+IVV++
Sbjct: 582 QEDFNKIMEYFEEELKRANFPPGVKAELAGESYLNYVLDNLVNEELGKISTIGTIIVVLI 641

Query: 600 VFAIFRRPTVSIAMIMPMFLGALWTIGYMGLAGIPFSQTLAGVVSMIVGLGVDYGMHITH 659
           VFAIFRRPTV++AMIMPMFLGALWTIGYMGLAGIPFSQTLAGVVSMIVGLGVDYGMHITH
Sbjct: 642 VFAIFRRPTVAVAMIMPMFLGALWTIGYMGLAGIPFSQTLAGVVSMIVGLGVDYGMHITH 701

Query: 660 RFLEELNEGNKTPIITALESVGPGIFVGALTTAGGFLALLSAQLTAIHDFGRVLAVGIFA 719
           RFLEEL EGNKTPIITA+ESVGPGI +GALTTAGGFLALL+ +LTAIHDFG+VLAVGIF+
Sbjct: 702 RFLEELKEGNKTPIITAMESVGPGILIGALTTAGGFLALLTGRLTAIHDFGKVLAVGIFS 761

Query: 720 SMFAAYLVTPAILQLEFGRKISKEVRE 746
           SM AAYLVTPAILQLEFGRKI KEV+E
Sbjct: 762 SMLAAYLVTPAILQLEFGRKI-KEVKE 787


>sp|Q58957|YF62_METJA PUTATIVE MEMBRANE PROTEIN MJ1562 >gi|2128938|pir||A64495
           hypothetical protein MJ1562 - Methanococcus jannaschii
           >gi|1592186|gb|AAB99583.1| (U67596) M. jannaschii
           predicted coding region MJ1562 [Methanococcus
           jannaschii]
           Length = 388
           
 Score =  255 bits (644), Expect = 2e-66
 Identities = 128/378 (33%), Positives = 229/378 (59%), Gaps = 8/378 (2%)

Query: 1   MLRKIARVIVIYRHS----LAVVTMFLLILSAYGITQLRFETDLSKQLPEDLEAVKSYFT 56
           MLR+I + +  +       + ++ + + + +    T ++ +T   K LP+D   +K+ + 
Sbjct: 5   MLREILKKVAHFSEQKPFLMLLIILIITVFAGISATNVKSQTAFEKMLPQDNPIIKTLYE 64

Query: 57  LQNEFGGSGSALIYVKIK---NNDNVVDIRDPKIIEAMYSLEQRLREKEYVTDTFSIADL 113
           +++EFGG+    I +K+K   ++D VVDIRDP++++A+  LE  LR  + +T   S  D+
Sbjct: 65  VRDEFGGTDVITICIKLKPSDSSDKVVDIRDPRVLKAIKELEDNLRYVDGITSVSSPVDI 124

Query: 114 MVQIL-GRLPKNMDEVKFVLNMLPPEARNGLISGDYSSTIIIVNLNREKNQKALVRVYND 172
           ++Q   G +P ++D VK +LN LP + R  + + DYS T++    +   +QK L+RV +D
Sbjct: 125 IIQKNNGIVPNDIDTVKDILNKLPEDKRKRIFNSDYSMTVVNAYTDAGGDQKKLMRVMDD 184

Query: 173 IEREIERTNFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIR 232
           +   IE T FP GVEV+ TG   +   + E+++   + T  +  I +++IL+ +++ P+ 
Sbjct: 185 VNERIEETPFPPGVEVIATGTPPMRKLMDELMKESQSFTTTVGLIGILIILIIYFRKPLS 244

Query: 233 MLVPLVPLIFGVVMTLGFMGLLGIPLDIATTTVGAMIIGMGIDYGVHVTNRYYEERGKGK 292
            ++PL+P++  V+ T G MGLL IPLD+AT  +G++I+G+GIDYG+H+ +RY EER KG 
Sbjct: 245 SIMPLLPVLIAVIWTGGAMGLLDIPLDMATAGIGSLILGLGIDYGIHLMHRYDEERRKGM 304

Query: 293 SLEEAAEEAIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIV 352
            +++A E A+ ETG A++    TT+ GFLAL ++ LP +  L     +G+    +  + +
Sbjct: 305 PIDKAIETAVVETGTAVMATTATTVVGFLALVLAPLPMMANLGKVCALGISFCMVVVLTL 364

Query: 353 TPALAILEEEFREKVMKK 370
            PAL ++EE     ++K+
Sbjct: 365 LPALIVIEERHIMPLIKR 382


 Score =  202 bits (509), Expect = 1e-50
 Identities = 115/359 (32%), Positives = 195/359 (54%), Gaps = 22/359 (6%)

Query: 395 KRSPWTALLIALIISGVSLYGASKITTEVRLEKMIPTDLPEIQALSDIRSEFGGQDEVTI 454
           ++ P+  LLI LII+  +   A+ + ++   EKM+P D P I+ L ++R EFGG D +TI
Sbjct: 18  EQKPFLMLLIILIITVFAGISATNVKSQTAFEKMLPQDNPIIKTLYEVRDEFGGTDVITI 77

Query: 455 LIKAD---------DVRDPTLVRDILRFEREIKADSYINNVFETQSIADVVIQKY-GYIP 504
            IK           D+RDP +++ I   E  ++   Y++ +    S  D++IQK  G +P
Sbjct: 78  CIKLKPSDSSDKVVDIRDPRVLKAIKELEDNLR---YVDGITSVSSPVDIIIQKNNGIVP 134

Query: 505 QDKEKISEAI------EGSSLVSSDYSMTIIKLKGNFMGVTQSEFNRIMEYFERAIQRAD 558
            D + + + +      +   + +SDYSMT++    +  G  Q +  R+M+     I+   
Sbjct: 135 NDIDTVKDILNKLPEDKRKRIFNSDYSMTVVNAYTD-AGGDQKKLMRVMDDVNERIEETP 193

Query: 559 FPPGVKVELAGESYLNYVLNDLVNEELGKISTIGTLIVVMVVFAIFRRPTVSIAMIMPMF 618
           FPPGV+V   G   +  ++++L+ E     +T+G + +++++   FR+P  SI  ++P+ 
Sbjct: 194 FPPGVEVIATGTPPMRKLMDELMKESQSFTTTVGLIGILIILIIYFRKPLSSIMPLLPVL 253

Query: 619 LGALWTIGYMGLAGIPFSQTLAGVVSMIVGLGVDYGMHITHRFLEELNEGN--KTPIITA 676
           +  +WT G MGL  IP     AG+ S+I+GLG+DYG+H+ HR+ EE  +G      I TA
Sbjct: 254 IAVIWTGGAMGLLDIPLDMATAGIGSLILGLGIDYGIHLMHRYDEERRKGMPIDKAIETA 313

Query: 677 LESVGPGIFVGALTTAGGFLALLSAQLTAIHDFGRVLAVGIFASMFAAYLVTPAILQLE 735
           +   G  +     TT  GFLAL+ A L  + + G+V A+GI   M     + PA++ +E
Sbjct: 314 VVETGTAVMATTATTVVGFLALVLAPLPMMANLGKVCALGISFCMVVVLTLLPALIVIE 372


>gi|11498828 conserved hypothetical protein [Archaeoglobus fulgidus]
           >gi|7430104|pir||D69403 conserved hypothetical protein
           AF1229 - Archaeoglobus fulgidus
           >gi|2649351|gb|AAB90013.1| (AE001019) conserved
           hypothetical protein [Archaeoglobus fulgidus]
           Length = 750
           
 Score =  231 bits (582), Expect = 3e-59
 Identities = 193/758 (25%), Positives = 359/758 (46%), Gaps = 49/758 (6%)

Query: 1   MLRKIARVIVIYRHSLAVVTMFLLILSAYGITQLRFETDLSKQLPEDLEAVKSYFTLQNE 60
           +L ++AR I      +  +   +LILSA+    +   +       +D    + Y   Q +
Sbjct: 5   LLDRVARFIARRPGFVISIISIILILSAFSAQNVGLTSGTESMFSKDNVIYRQYKLYQKD 64

Query: 61  FGGSGSALIYVKIKNNDNVVDIRDPKIIEAMYSLEQRLREKEYVTDTFSIADLMVQILGR 120
           FG  G+  ++V IK +D V    + ++ + +  L++R+ E E V+   S A ++  + G 
Sbjct: 65  FG-VGADQLFVLIKGDDVV----NSEVYQYLLDLQKRIEEIEGVSSVVSPASIVSSLYGG 119

Query: 121 LPKNMDEVKFVLNMLPPEARNGLISGDYSSTIIIVNLNREKNQKALVRVYNDIEREIERT 180
           LP +  ++    ++   +     +    +  ++I+ L    + K    +  ++E+ I  T
Sbjct: 120 LPSDESKISIATSLYASD-----LVPKPTLAMMIIQLGTADDTKQ-EEIAIEVEKVISFT 173

Query: 181 NFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRM----LVP 236
           N P G+ + LTG   ++Y+I   +      TM +S I++VL+L   +   +R      +P
Sbjct: 174 NPPHGLVLQLTGGPALSYQIEREIGKSFGITMMVSIILMVLLLFLTFSGAVRKKYTAFLP 233

Query: 237 LVPLIFGVVMTLGFMGLLGIPLDIATTTVGAMIIGMGIDYGVHVTNRYYEERGKGKSLEE 296
           LV  +  V +  G M +LGIPL   T     M+IG+ I+YG  + NRY EER +G+ +++
Sbjct: 234 LVISVMSVTVVYGLMPILGIPLSEHTNGALPMLIGLAIEYGAQLQNRYEEERREGRDVDD 293

Query: 297 AAEEAIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVTPAL 356
           A   +I  TG A++ A +TT+ GF+++    +P++ +  +   +GL +A L  +   PA+
Sbjct: 294 AVVISITRTGLAIVMALITTVIGFMSMLAPGMPAMAQFGIISSLGLIVAYLLTLTFLPAV 353

Query: 357 AILEEEFRE-KVMKKKEIIAIGGGKSKISFIFSMLGKAIKRSPWTALLIALIISGVSLYG 415
             L + + + K  K++E  ++G  +  +S I ++        P   L+ A II    LY 
Sbjct: 354 LKLIDHWNDAKEQKREEEKSVGTLERSLSAISTLTA----TRPVGILVAASIIVLFGLYA 409

Query: 416 ASKITTEVRLEKMIPTDLPEIQALSDIRSEFGGQDEVTILIKADDVRDPTLVRDILRFER 475
           A +I  E    K +P DL  +Q   +I    GGQ   T++++ D++   TL       + 
Sbjct: 410 APQIGLETNYNKYVPQDLTAMQRFKEIERLVGGQATYTLVLEVDELNAETLKEIDELSKY 469

Query: 476 EIKADSYINNVFETQSIADVVIQKYGY--IPQDKEKISEAIEGSSLVSSDYSMTII--KL 531
            ++ +  I +      +   V + YG+  +P+   ++ + +  S+L   + S  I   ++
Sbjct: 470 IVEKEELIYDYSSITKLISEVRKAYGFEGLPESDAELMQIL--SALPQEEVSRYISGGQI 527

Query: 532 KGNFMGVTQSEFNRIMEYFERAIQRADFPPGVKVELAGESYLNYVL-NDLVNEELGKIST 590
             +F     S+   I  +  ++I R        VE  G S   YV    ++  E+G++ T
Sbjct: 528 AVHFSSNADSQDEYISTH--KSIVR-------DVEFFGWSGGYYVTGGPVIYGEMGRLMT 578

Query: 591 IGT--------LIVVMVVFAIFR--RPTVSIAMIMPMFLGALWTIGYMGLAGIPFSQTLA 640
            G          +++M++ A++R  R  V   + +   +GA+ TI  M L G   +    
Sbjct: 579 SGQTTMTVVAYALIIMLLLAVYRSIRKAVVPLIAITSVIGAMNTI--MFLTGTKQTMISI 636

Query: 641 GVVSMIVGLGVDYGMHITHRFLEELNEGNKTPII-TALESVGPGIFVGALTTAGGFLALL 699
            + S+ +GLG+D+ +H+  R+ EE    +    +   +E  G  I   ALT AGGF +L+
Sbjct: 637 ALNSITLGLGIDFSIHVLERYFEERAAFSPVEAVRRTIERTGKAITTSALTMAGGFGSLM 696

Query: 700 SAQLTAIHDFGRVLAVGIFASMFAAYLVTPAILQLEFG 737
            +    + +FG +  V I  S+ AA  V PA L L  G
Sbjct: 697 FSTFPIMQNFGFIALVAILFSLLAALTVVPAFLMLTEG 734


 Score =  115 bits (285), Expect = 2e-24
 Identities = 87/360 (24%), Positives = 174/360 (48%), Gaps = 23/360 (6%)

Query: 16  LAVVTMFLLILSAYGITQLRFETDLSKQLPEDLEAVKSYFTLQNEFGGSGSALIYVKIKN 75
           + V    +++   Y   Q+  ET+ +K +P+DL A++ +  ++   GG  +  + ++   
Sbjct: 395 ILVAASIIVLFGLYAAPQIGLETNYNKYVPQDLTAMQRFKEIERLVGGQATYTLVLE--- 451

Query: 76  NDNVVDIRDPKIIEAMYSLEQRLREKE-YVTDTFSIADLMVQI-----LGRLPKNMDEVK 129
               VD  + + ++ +  L + + EKE  + D  SI  L+ ++        LP++  E+ 
Sbjct: 452 ----VDELNAETLKEIDELSKYIVEKEELIYDYSSITKLISEVRKAYGFEGLPESDAELM 507

Query: 130 FVLNMLPPEARNGLISGDYSSTIIIVNLNREKNQKALVRVYNDIEREIERTNFPQGVEVV 189
            +L+ LP E  +  ISG   +     N +   +Q   +  +  I R++E   +  G  V 
Sbjct: 508 QILSALPQEEVSRYISGGQIAVHFSSNAD---SQDEYISTHKSIVRDVEFFGWSGGYYV- 563

Query: 190 LTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPLVPL--IFGVVMT 247
            TG   I  ++  ++ +       ++  +++++LL  Y+S  + +VPL+ +  + G + T
Sbjct: 564 -TGGPVIYGEMGRLMTSGQTTMTVVAYALIIMLLLAVYRSIRKAVVPLIAITSVIGAMNT 622

Query: 248 LGFMGLLGIPLDIATTTVGAMIIGMGIDYGVHVTNRYYEERGKGKSLEEAAEEAIAETGK 307
           + F  L G    + +  + ++ +G+GID+ +HV  RY+EER     +E A    I  TGK
Sbjct: 623 IMF--LTGTKQTMISIALNSITLGLGIDFSIHVLERYFEERAAFSPVE-AVRRTIERTGK 679

Query: 308 ALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVTPALAILEEEFREKV 367
           A+  +ALT   GF +L  S  P ++      ++ +  + L A+ V PA  +L E    ++
Sbjct: 680 AITTSALTMAGGFGSLMFSTFPIMQNFGFIALVAILFSLLAALTVVPAFLMLTEGIEARI 739


>gi|11498071 conserved hypothetical protein [Archaeoglobus fulgidus]
           >gi|7430103|pir||C69307 conserved hypothetical protein
           AF0459 - Archaeoglobus fulgidus
           >gi|2650170|gb|AAB90778.1| (AE001073) conserved
           hypothetical protein [Archaeoglobus fulgidus]
           Length = 736
           
 Score =  203 bits (512), Expect = 5e-51
 Identities = 170/683 (24%), Positives = 314/683 (45%), Gaps = 54/683 (7%)

Query: 69  IYVKIKNNDNVVDIRDPKIIEAMYSLEQRLREKEYVTDTFSIADLMVQILGRLPKNMDEV 128
           +Y+ +K  D    +    ++E M SL++ L  ++ V  T S A ++  +LG +P + + V
Sbjct: 78  VYIIVKAED----VLSRDVMEYMLSLQKVLEGRDGVVSTSSPASILRDVLGDIPDSEELV 133

Query: 129 KFVLNMLPPEARNGLISGDYSSTIIIVNLNREKNQKALVRVYNDIEREIERTNFPQGVEV 188
                 L        +  + S  +I V +   +N + L+ +  +IER ++  + P GV V
Sbjct: 134 GETAERLAKS-----LLPERSFALISVQIESMENDR-LMELAEEIERILQFVSPPPGVVV 187

Query: 189 VLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIR----MLVPLVPLIFGV 244
            +TG   + Y+I + ++ D+ RT  I+ + ++ +L+  +   +R    +L PL+  +  V
Sbjct: 188 DVTGGAVLMYQIAKAVEEDVYRTFFIASVTMIAVLVAVFSGVVRSKLTVLFPLIVSLMSV 247

Query: 245 VMTLGFMGLLGIPLDIATTTVGAMIIGMGIDYGVHVTNRYYEERGKGKSLEEAAEEAIAE 304
            +  G + LLG+ +    +    ++IG+ IDY   + NRY EER  G+ ++EA EEA+  
Sbjct: 248 AVMAGLLPLLGLQMTEYNSATIPILIGLAIDYAAQLQNRYEEERRGGREVDEALEEALNH 307

Query: 305 TGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVTPALAILEEEFR 364
           T   L  A  TT+ GF ++    +PSL   S  L +GL  A L +    P+L  L +   
Sbjct: 308 TRFPLFMAMATTVIGFASMCAPGIPSLFWFSFLLSVGLITAFLLSNTFLPSLLKLSDR-- 365

Query: 365 EKVMKKKEIIAIGGGKSKIS-----FIFSMLGKAIKRSPWTALLIALIISGVSLYGASKI 419
                       GG +  IS      + + + K    +    L + LI+  V  Y ++ +
Sbjct: 366 ------------GGREESISPGILEKLLTTIAKVTIANSRKILALTLILIVVGAYASTHV 413

Query: 420 TTEVRLEKMIPTDLPEIQALSDIRSEFGGQDEVTILIKADDVRDPTLVRDILRFEREIKA 479
             E    K  P DLP +    +I  +   Q    +++  + +        +++ E   K 
Sbjct: 414 ELETNRRKYAPPDLPALVKFEEIERKVSPQYVYALVLSTERID----AESVVKAEELAKY 469

Query: 480 DSYINNVFETQSIADVVIQKYGYIPQDKEKISEAIEGSSLVSSDYSMTIIKLKGNFMGV- 538
            S    +++  S+   + + YG IP   E  S+AI+  +L  S YS  I    GN + V 
Sbjct: 470 ISSREEIYDYDSLGKTLEEYYGAIP--AESFSKAID--ALPKSIYSRFI---SGNQLAVY 522

Query: 539 ------TQSEFNRIMEYFERAIQRADFPPGVKVELAGESYLNYVLNDLVNEELGKISTIG 592
                 T+ E  ++M   E  ++  ++     +   G   +   L++++   L  ++ + 
Sbjct: 523 FYTNTQTEEEVEKMMRSIENDLRFLEWDGDYYI--TGFPVILGHLSEVLFSSLNLMTLVA 580

Query: 593 TLIVVMVVFAIFRRPTVSIAMIMPMFLGALWTIGYMGLAGIPFSQTLAGVVSMIVGLGVD 652
            L++V  +   +R    +I  ++ + +        M L GI  +     + S+++G+G+D
Sbjct: 581 YLLIVTFLLLAYRSVVRAIIPLISISVAVASMNVCMLLMGIKQTTISIALNSIVLGMGID 640

Query: 653 YGMHITHRFLEELNE-GNKTPIITALESVGPGIFVGALTTAGGFLALLSAQLTAIHDFGR 711
           Y +HIT R+ EE  + G +  +   +E  G  +   ALTTAGGF AL  +    + +FG 
Sbjct: 641 YSIHITERYFEERGKFGVEESVKRTVERTGKAVLTSALTTAGGFGALYFSTFPVLSNFGI 700

Query: 712 VLAVGIFASMFAAYLVTPAILQL 734
           +  + I  S+ AA    PA+L L
Sbjct: 701 LAFIAIIFSLLAATSAVPALLIL 723


 Score =  146 bits (364), Expect = 1e-33
 Identities = 97/367 (26%), Positives = 178/367 (48%), Gaps = 17/367 (4%)

Query: 1   MLRKIARVIVIYRHSLAVVTMFLLILSAYGITQLRFETDLSKQLPEDLEAVKSYFTLQNE 60
           +L  IA+V +     +  +T+ L+++ AY  T +  ET+  K  P DL A+  +  ++ +
Sbjct: 380 LLTTIAKVTIANSRKILALTLILIVVGAYASTHVELETNRRKYAPPDLPALVKFEEIERK 439

Query: 61  FGGSGSALIYVKIKNNDNVVDIRDPKIIEAMYSLEQRLREKEYVTDTFSIADLMVQILGR 120
                   +Y  + + + +    D + +     L + +  +E + D  S+   + +  G 
Sbjct: 440 VSPQ---YVYALVLSTERI----DAESVVKAEELAKYISSREEIYDYDSLGKTLEEYYGA 492

Query: 121 LPKNMDEVKFVLNMLPPEARNGLISGDYSSTIIIVNLNREKNQKALVRVYNDIEREIERT 180
           +P   +     ++ LP    +  ISG+  +     N   E+  + ++R   +  R +E  
Sbjct: 493 IPA--ESFSKAIDALPKSIYSRFISGNQLAVYFYTNTQTEEEVEKMMRSIENDLRFLEWD 550

Query: 181 NFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPLVPL 240
                 +  +TG   I   + E+L + +N    ++ +++V  LL  Y+S +R ++PL+ +
Sbjct: 551 G-----DYYITGFPVILGHLSEVLFSSLNLMTLVAYLLIVTFLLLAYRSVVRAIIPLISI 605

Query: 241 IFGVVMTLGFMGLLGIPLDIATTTVGAMIIGMGIDYGVHVTNRYYEERGKGKSLEEAAEE 300
              V      M L+GI     +  + ++++GMGIDY +H+T RY+EERGK   +EE+ + 
Sbjct: 606 SVAVASMNVCMLLMGIKQTTISIALNSIVLGMGIDYSIHITERYFEERGKF-GVEESVKR 664

Query: 301 AIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVTPALAILE 360
            +  TGKA+L +ALTT  GF AL  S  P L    +   + +  + L A    PAL IL 
Sbjct: 665 TVERTGKAVLTSALTTAGGFGALYFSTFPVLSNFGILAFIAIIFSLLAATSAVPALLILY 724

Query: 361 EE--FRE 365
           E+  FRE
Sbjct: 725 EKNYFRE 731


>gb|AAG19780.1| (AE005063) Vng1476c [Halobacterium sp. NRC-1]
           Length = 746
           
 Score =  173 bits (435), Expect = 5e-42
 Identities = 167/680 (24%), Positives = 293/680 (42%), Gaps = 53/680 (7%)

Query: 81  DIRDPKIIEAMYSLEQRLREKEYVTDTFSIADLMVQILGRLPKNMDEVKFVLNMLPPEAR 140
           DI +P  IEA+   ++R+ + + V    S AD +    GR+P +  +++ V+        
Sbjct: 75  DITEPSAIEAIDRYDRRMSQTQDVYAVRSPADQVRAAYGRIPDSKSKIESVIG------- 127

Query: 141 NGLISGDYSSTIIIVNLNREKNQKALVRVYNDIEREIERTNFPQGVEVVLTGDLGITYKI 200
               S DY++  I  + +  + Q+    +Y +     +   FP  V   +TGD   + ++
Sbjct: 128 ----SPDYTTIQIATDTDLTQQQQR--PIYTEAVSTSDWARFPASVTATVTGDAAFSAQL 181

Query: 201 LEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPLVPLIFGVVMTLGFMGLLGIPLDI 260
             ++Q    + + ++  ++V+ L + ++     L+P+V +  GV+ T G +G  GIP   
Sbjct: 182 STVIQQSTQKLLGLAVGLMVIALFFLFRGVRLRLLPIVAVFVGVIYTFGAIGYGGIPNST 241

Query: 261 ATTTVGAMIIGMGIDYGVHVTNRYYEERGKGKSLEEAAEEAIAETGKALLGAALTTIAGF 320
            T+ V  ++IG+GIDY V    R YEE  +     EA   A+   G  +L A L    GF
Sbjct: 242 MTSAVFPILIGLGIDYSVQFHER-YEEELETHPPREALPNALGGVGPPVLIAMLAAALGF 300

Query: 321 LALSISI-LPSLKRLSVSLVMGLGLA-ALNAVIVTPALAILEEEFREKVMKKKEIIAIGG 378
            A  +S   P++   + + ++G+ L  A   +++   L I    + +         A GG
Sbjct: 301 GATWVSTSSPAIIWFAQTSILGVLLTYAAGILVLLAGLTIYIRRWGD----DSPAAADGG 356

Query: 379 G----------KSKISFIFSMLGKA---IKRSPWTALLIALIISGVSLYGASKITTEVRL 425
                       S+I  + S LG+    +   P T L IAL++SGV    AS + T    
Sbjct: 357 DPEAAHAEVDEDSRIGLVGSTLGRTSRILASHPMTVLAIALVLSGVGFQVASSLGTLADT 416

Query: 426 EKMIPTDLPEIQALSDIRSEFGGQDEVT--ILIKADDVRDPTLVRDILRFEREIKADSYI 483
           E+ IP DLP    L   RS+ GG    +  +L+    ++ P    + LR+   +   +  
Sbjct: 417 EEFIPQDLPAYVDLQQFRSQTGGGTSTSYDVLVTGTHLKHP----ETLRWMDGLNDVATQ 472

Query: 484 NNVFETQSIADVVIQKY--GYIPQDKEKISEAI-----EGSSLVSSDYSMTIIKLKGNFM 536
             + E        +++Y  G IP+    +   +     E      +D    I       M
Sbjct: 473 APLVEGVDTPAGAVKQYNGGEIPRTTSGVERVLAQMPTEQRQRYYNDGRAHITVASPQDM 532

Query: 537 GVTQSEFNRIMEYFERAIQRADFPPGVKVELAGESYLNY-VLNDLVNEELGKISTIGTLI 595
             T  +    +E  + ++  ++ PPGV  E+ G S +    + D +N      + +G L 
Sbjct: 533 --TTGQVLSFLENSQESLDYSNPPPGVTAEVTGTSSIAVPSIIDQINSR-NTTTGLGILF 589

Query: 596 VVMVVFAIFRRPTVSIAMIMPMFLGALWTIGYMGLAGIPFSQTLAGVVSMIVGLGVDYGM 655
           V  ++   +R    ++A ++PM     W   YM    IP S   A + +M VG+G +Y +
Sbjct: 590 VFALLGLYYRDLVKAVAPLVPMVFVIGWQNIYMLALDIPVSPLGASLGAMTVGIGAEYTI 649

Query: 656 HITHRFLEELNE---GNKTPIITALESVGPGIFVGALTTAGGFLALLSAQLTAIHDFGRV 712
            +  R+ EE      G    +  A   VG  I V  +TT  GF AL+ +    +  FG +
Sbjct: 650 IVMERYYEEKQHNGYGRLDAVEIAASRVGKAITVSGMTTVFGFSALILSPFPVLSSFGFL 709

Query: 713 LAVGIFASMFAAYLVTPAIL 732
               IF ++ A+    P  L
Sbjct: 710 TVGVIFLTLIASLATLPPTL 729


 Score =  121 bits (300), Expect = 3e-26
 Identities = 97/359 (27%), Positives = 171/359 (47%), Gaps = 19/359 (5%)

Query: 382 KISFIFSMLGKAIKRSPWTALLIALIISGVSLYGASKITTEVRLEKMIPTDLPEIQALSD 441
           K+   F+ +G  ++  P   LLIA ++  V++ GA++IT+    +  + ++ P  +A SD
Sbjct: 3   KLRSAFASIGDRVQARPVATLLIAGLLILVAIGGAAQITSVTGDDAFVGSN-PTYEAFSD 61

Query: 442 IRSEFGGQDEVTILIKADDVRDPTLVRDILRFEREIKADSYINNVFETQSIADVVIQKYG 501
                     + +LI+ D + +P+ +  I R++R +   S   +V+  +S AD V   YG
Sbjct: 62  SFDH----GNIAVLIRGD-ITEPSAIEAIDRYDRRM---SQTQDVYAVRSPADQVRAAYG 113

Query: 502 YIPQDKEKISEAIEGSSLVSSDYSMTIIKLKGNFMGVTQSEFNRIMEYFERAIQRADFPP 561
            IP  K KI   I      S DY+   I    +   +TQ +   I          A FP 
Sbjct: 114 RIPDSKSKIESVIG-----SPDYTTIQIATDTD---LTQQQQRPIYTEAVSTSDWARFPA 165

Query: 562 GVKVELAGESYLNYVLNDLVNEELGKISTIGTLIVVMVVFAIFRRPTVSIAMIMPMFLGA 621
            V   + G++  +  L+ ++ +   K+  +   ++V+ +F +FR   + +  I+ +F+G 
Sbjct: 166 SVTATVTGDAAFSAQLSTVIQQSTQKLLGLAVGLMVIALFFLFRGVRLRLLPIVAVFVGV 225

Query: 622 LWTIGYMGLAGIPFSQTLAGVVSMIVGLGVDYGMHITHRFLEEL-NEGNKTPIITALESV 680
           ++T G +G  GIP S   + V  +++GLG+DY +    R+ EEL     +  +  AL  V
Sbjct: 226 IYTFGAIGYGGIPNSTMTSAVFPILIGLGIDYSVQFHERYEEELETHPPREALPNALGGV 285

Query: 681 GPGIFVGALTTAGGFLAL-LSAQLTAIHDFGRVLAVGIFASMFAAYLVTPAILQLEFGR 738
           GP + +  L  A GF A  +S    AI  F +   +G+  +  A  LV  A L +   R
Sbjct: 286 GPPVLIAMLAAALGFGATWVSTSSPAIIWFAQTSILGVLLTYAAGILVLLAGLTIYIRR 344


 Score =  103 bits (255), Expect = 6e-21
 Identities = 90/358 (25%), Positives = 160/358 (44%), Gaps = 15/358 (4%)

Query: 10  VIYRHSLAVVTMFLLILSAYGI---TQLRFETDLSKQLPEDLEAVKSYFTLQNEFGGSGS 66
           ++  H + V+ +  L+LS  G    + L    D  + +P+DL A       +++ GG  S
Sbjct: 384 ILASHPMTVLAI-ALVLSGVGFQVASSLGTLADTEEFIPQDLPAYVDLQQFRSQTGGGTS 442

Query: 67  ALIYVKIKNNDNVVDIRDPKIIEAMYSLEQRLREKEYVTDTFSIADLMVQILG-RLPKNM 125
               V +        ++ P+ +  M  L     +   V    + A  + Q  G  +P+  
Sbjct: 443 TSYDVLVTGTH----LKHPETLRWMDGLNDVATQAPLVEGVDTPAGAVKQYNGGEIPRTT 498

Query: 126 DEVKFVLNMLPPEARNGLISGDYSSTIIIVNLNREKNQKALVRVYNDIEREIERTNFPQG 185
             V+ VL  +P E R    +   +   I V   ++     ++    + +  ++ +N P G
Sbjct: 499 SGVERVLAQMPTEQRQRYYNDGRAH--ITVASPQDMTTGQVLSFLENSQESLDYSNPPPG 556

Query: 186 VEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPLVPLIFGVV 245
           V   +TG   I    +    N  N T  +  + V  +L  +Y+  ++ + PLVP++F + 
Sbjct: 557 VTAEVTGTSSIAVPSIIDQINSRNTTTGLGILFVFALLGLYYRDLVKAVAPLVPMVFVIG 616

Query: 246 MTLGFMGLLGIPLDIATTTVGAMIIGMGIDYGVHVTNRYYEERG-KGKSLEEAAEEAIAE 304
               +M  L IP+     ++GAM +G+G +Y + V  RYYEE+   G    +A E A + 
Sbjct: 617 WQNIYMLALDIPVSPLGASLGAMTVGIGAEYTIIVMERYYEEKQHNGYGRLDAVEIAASR 676

Query: 305 TGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVT--PALAILE 360
            GKA+  + +TT+ GF AL +S  P L      L +G+    L A + T  P L +L+
Sbjct: 677 VGKAITVSGMTTVFGFSALILSPFPVLSSFGF-LTVGVIFLTLIASLATLPPTLVVLD 733


>pir||D70131 conserved hypothetical integral membrane protein BB0252 - Lyme
           disease spirochete >gi|2688146|gb|AAB91494.1| (AE001135)
           conserved hypothetical integral membrane protein
           [Borrelia burgdorferi]
           Length = 767
           
 Score =  145 bits (363), Expect = 1e-33
 Identities = 165/768 (21%), Positives = 345/768 (44%), Gaps = 73/768 (9%)

Query: 13  RHSLAVVTMFLLILSAYG--ITQLRFETDLSKQLPEDLEAVKSYFTLQNEFGGSGSALIY 70
           R+   + T+F+LI    G  +  L+F+ ++ K +P+  E          +   S S L  
Sbjct: 9   RYKGIIFTIFILITIFLGFFLKNLKFDANILKLIPKTKETESLI-----DIDKSNSLLST 63

Query: 71  VKI-KNNDNVVDIRDPKIIEAMYSLEQRLRE--KEYVTDTFSIADLMVQILGRLPKNMDE 127
           + I ++  N+ + ++ + I ++ S   ++ +     VT  FS      + +    K+++E
Sbjct: 64  IVIFQDKKNIFNKKNFETINSVISEITKILKVSPNAVTSIFSYFPQFKKEI-YTDKDIEE 122

Query: 128 VKFVLNMLPPEARNGLISGDYSSTIIIVNLNREKNQ----KALVRVYNDIEREIERTNFP 183
           +K  +   P      L  G+  + I  + +  E +Q    + L    +++E+ I++    
Sbjct: 123 IKSKIKSTPFVKNTFL--GNSENLIYFIIIPSESDQINFSRNLKTELDEMEKTIKKYE-T 179

Query: 184 QGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPLVPLIFG 243
             +++ LTGDL +  KIL  +  D      ++  +V++ L    K+ I  L+P+   +  
Sbjct: 180 DDLKLYLTGDLIVREKILNYMVEDFKILGPLATFVVIISLYLIIKNLIGALIPIFIALLS 239

Query: 244 VVMTLGFMGLLGIPLDIATTTVGAMIIGMGIDYGVHVTNRYYEERGKGKSLEEAAEEAIA 303
           ++ T G  GL+  P+ +  T++  ++I +G    VH+ N  ++   K +  +E+ +  I 
Sbjct: 240 LIWTFGIKGLVQSPITVPETSMIVLLISIGCANAVHIINEIFKLIKKEQLSKESIKATIK 299

Query: 304 ETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVTPALAILEEEF 363
           +    +L  + TT  GFL+L+ S + + K + + + +G+ ++ + ++ V P +  L    
Sbjct: 300 KLKTPILLTSFTTAFGFLSLTTSSINAYKTMGIFMSIGVIISMIISLTVLPGIITLIPFA 359

Query: 364 REKVMKKKEIIAIGGGKSKISF------IFSMLGKAIKRSPWTALLIALIISGVSLYGAS 417
           ++K  +K++   +    +KISF      + + + K+I +  +T+ ++ LII G+S  G  
Sbjct: 360 KKKSFEKEKENKL----NKISFLERLAKLNTQITKSILKRKYTSSIMVLIILGISFVGLL 415

Query: 418 KITTEVRLEKMIPTDLPEIQALSDIRSEFGGQDEVTILI----------KADDVRDPTLV 467
           KI      +          + L+ ++ E GG     I I          KA  + D  L+
Sbjct: 416 KIEINFDEKDYFKESTSVKKTLNLMQKEMGGISIFKIEIEGRPGEFKNAKAMQILD--LI 473

Query: 468 RDILRFEREIKADSYINNVFETQSIADVVIQKYGY-IPQDK---EKISEAIEGSS----- 518
            D L         S IN + +  +          Y +P++K    K+   I+ S      
Sbjct: 474 TDKLDAFSAKTQSSSINGILKFTNFKIKKESPLEYKLPENKIILNKLINLIDKSDWTKDN 533

Query: 519 ---LVSSDYSM--TIIKLKGNFM-GVTQSE---FNRIMEYFERAIQRADFPPGVKVELAG 569
               ++ D+S+   I++++ N   G+ + E    N I EY +            K   +G
Sbjct: 534 KRMYINDDWSLISIIVRIEDNSTEGIKKFEKYAINTINEYMKNN----------KYHFSG 583

Query: 570 ESYLNYVLNDLVNEE-LGKISTIGTLIVVMVVFAIFRRPTVSIAMIMPMFLGALWTIGYM 628
                 +   +V E+ +  I+T+G++ ++++ F  F+     I + +P+          M
Sbjct: 584 VYDKVLIAKTMVKEQVINIITTLGSITLLLMFF--FKSIKTGIIIAIPVAWSVFLNFAVM 641

Query: 629 GLAGIPFSQTLAGVVSMIVGLGVDYGMHITHRFL--EELNEGNKTPIITALESVGPGIFV 686
            L GI  +   A + S+ +G+GVDY +H  + F+   + N+  KT ++ ++ +V  GIF 
Sbjct: 642 RLFGITLNPATATIASVSMGVGVDYSIHFFNTFILQYQKNQIYKTALLESIPNVFNGIFA 701

Query: 687 GALTTAGGFLALLSAQLTAIHDFGRVLAVGIFASMFAAYLVTPAILQL 734
            +++   GFL L  +    I   G ++A  +  +  A+  + P ++ L
Sbjct: 702 NSISVGIGFLTLTFSSYKIISTLGAIIAFTMLTTSLASLTLLPLLIYL 749


>pir||E72272 conserved hypothetical protein - Thermotoga maritima (strain MSB8)
           >gi|4981852|gb|AAD36368.1|AE001784_10 (AE001784)
           conserved hypothetical protein [Thermotoga maritima]
           Length = 694
           
 Score =  141 bits (352), Expect = 3e-32
 Identities = 166/755 (21%), Positives = 329/755 (42%), Gaps = 86/755 (11%)

Query: 1   MLRKIARVIVIYRHSLAVVTMFLLILSAYGITQLRFETDLSKQLPEDLEAVKSYFTLQNE 60
           M  K    +   R  +  + + + IL+ +G+ +L F T+ S  +P+     + Y  +   
Sbjct: 1   MFEKYTSFVFKNRKRIFALVLVINILALFGLFRLHFTTEFSILMPQKSHQKEIYDRMNTI 60

Query: 61  FGGSGSALIYVKIKNNDNVVDIRDPKIIEAMYSLEQRLREKEYVT---DTFSIADLMVQI 117
           F       + VK+ N D +      K+ E    L      K  +T   + F +   +V+ 
Sbjct: 61  FKSGEQLAVMVKM-NTDPLSREGLNKVFEIKERLSSIEGVKTVITPVPEKFPVGFRLVET 119

Query: 118 LGRLPKNMDE-------VKFVLNMLPPEARNGLISGDYSSTIIIV--NLNREKNQKALVR 168
            G   K  ++       VK +LN+   +       G Y+  +I+   ++  EK +K L  
Sbjct: 120 KGMAEKEYEDFLSYVQSVKDLLNVKKTD------DGYYALFMILPEESVPPEKIEKVL-- 171

Query: 169 VYNDIEREIERTNFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYK 228
             +D E  +  T + +           I   +L M+         +    VVL+L  F  
Sbjct: 172 --SDYEHYLSGTQYLEDQ---------IFRYLLFMI-------FTLPPFAVVLLLNVFRV 213

Query: 229 SPIRM---LVPLVPLIFGVVMTLGF-MGLLGIPLDIATTTVGAMIIGMGIDYGVHVTNRY 284
              R    +  L+P  F  + TLG  MG  G  L I T  V    I MG   G+H  + +
Sbjct: 214 QLGRFKYAIFSLIPAGFAALWTLGIVMGWFGQDLSIITFLVPIFTIVMGSADGLHFVSHF 273

Query: 285 YEERGKGKSLEEAAEEAIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGL 344
            E + +G++   A +  +   G+A++   LTT+AGFL+       S+K++ V   +G+GL
Sbjct: 274 LERKREGETTFNAVKNTLESVGRAMILTTLTTMAGFLSFLTLNSESMKQMGVLASIGIGL 333

Query: 345 AALNAVIVTPALAILEEEFREKVMKKKEIIAIGGGKSKISFIFSMLGKAIKRSPWTALLI 404
           A ++  IV P +    E+                 K+K S +F +  K  KR    AL++
Sbjct: 334 AGVSTWIVLPVILSRVEKVEP--------------KNKESGVFRVFQKLSKR----ALVV 375

Query: 405 ALIISGVSLYGASKITTEVRLEKMIPTDLPEIQALSDIRSEFGGQDEVTILIKADDVRDP 464
            ++   + L G   +  ++ + K+  +     + +  I   FG    V IL +++++ DP
Sbjct: 376 TIVSVLIFLPGLFFLKADLNILKLYKSYTRVRKNVEKIEEVFGRALPVYILFESENLFDP 435

Query: 465 TLVRDILRFEREIKADSYINNVFETQSIADVVIQKYGYIPQDK---EKISEAIEGSSLVS 521
           +  + +L  E ++K +      F+  S+ D++ +    + ++K   + ++ A+    L+ 
Sbjct: 436 SFAQKVLSMEEDLKKEG-----FDAFSMYDIISKLNERLFKEKGYPKILARALILKRLLP 490

Query: 522 SDYSMTIIKLKGNFMGVTQSEFNR-IMEYFERAIQRADFPPGVKVELAGESYLNYVLND- 579
            +Y+  ++        V  ++ +R I+   E  +++  F      ++ G  Y+   +ND 
Sbjct: 491 DEYTENLVSGNTGRAFVFLNDLDREILVKVENVVEKHGF------QVTGIPYIIKEMNDS 544

Query: 580 LVNEELGKISTIGTLIVVMVVFAIFRRPTVSIA-MIMPMFLGALWTIGYMGLAGIPFSQT 638
           +V ++L  +S    + +V ++  +F+R  +  A  I+P+ +  +   G+MGL+GIP +  
Sbjct: 545 IVPQQL--LSVFLAISMVFLLLVLFQRSFLYPAKAIVPVGISLVSLFGFMGLSGIPLNLI 602

Query: 639 LAGVVSMIVGLGVDYGMHITHRFLEELNEGNKTPIITALESVGPGIFVGALTTAGGFLAL 698
            A +  +++G+G+DY +H+T  F     +  KT  I +       +   A   + G  AL
Sbjct: 603 TANMAGIVIGVGIDYAIHVTELF-RYYGDIEKTVRIASTP-----VLANAFGLSIGLSAL 656

Query: 699 LSAQLTAIHDFGRVLAVGIFASMFAAYLVTPAILQ 733
           + +  T       ++ V +  S F + ++ P +L+
Sbjct: 657 ILSPFTFHTYLVAIMWVTMTVSSFMSLVILPKLLE 691


>sp|O54101|MMLB_STRCO PUTATIVE MEMBRANE PROTEIN SC10A5.10C >gi|7480675|pir||T34577
           probable export protein - Streptomyces coelicolor
           >gi|2815318|emb|CAA16442.1| (AL021529) SC10A5.10c,
           probable export protein, len: 847 aa; si milar to eg. S.
           coelicolor actinorhodin antibiotic export p rotein
           TR:Q53902 (EMBL:M64683) ORF2 (ACTII) (711 aa), fasta
           scores; opt: 705 z-score: 1126.2 E(): 0, 35.4% identity
           in 746 aa ov>
           Length = 847
           
 Score =  115 bits (285), Expect = 2e-24
 Identities = 152/632 (24%), Positives = 259/632 (40%), Gaps = 69/632 (10%)

Query: 128 VKFVLNMLPPEARNGLISGDYSSTIIIVNLNREKNQKALVRVYNDIEREIERTNFPQGVE 187
           V  V  +  P+A   L+S D  + ++IV +    + ++     +++         P   +
Sbjct: 111 VSVVSTVTAPDAAAELVSQDRGAQLVIVPMEGSPSDESFQNAVDEVRALASDRAGP--AD 168

Query: 188 VVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPLVPLIFGVVM- 246
           V +TG  GI    +++        +  + ++V++ILL  Y+SP+  LVPL  L  GV M 
Sbjct: 169 VAVTGPAGIATDTVKVFSGGDKVLLLATVVLVLIILLAIYRSPLMALVPL--LAVGVAMR 226

Query: 247 ---TLGFMGLLGIPLDIATTTVGAMII---GMGIDYGVHVTNRYYEERGKGKSLEEAAEE 300
              TLG +      + +++ T   M +   G+G DY + +T RY E          A + 
Sbjct: 227 VAETLGAILADAGVITVSSQTASIMTVLLFGVGTDYALIITARYRETLLDEPDRARAMQA 286

Query: 301 AIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVTPALAIL- 359
           A+  T +++L +A T +    AL +++ P+L      L +G+ + AL A    PAL +L 
Sbjct: 287 AVRRTAESVLASASTIVLAMFALLVAVSPALHGFGPYLALGVAVMALVAFTFIPALVLLL 346

Query: 360 -EEEFREKVMKKKEIIAIGGGKSKISFIFSMLGKAIKRSP---WTALLIALIISGVSLYG 415
               F    + K    + G G      I+  +   + R+P    +A++  L++    L G
Sbjct: 347 GRSVFWPGGVDKAAERSRGAG------IWHRIAALVARAPVKVASAVIALLVVLSAGLLG 400

Query: 416 ASKITTEVRLEKMIPTDLPEIQALSDIRSEFGGQD---EVTILIKADDVRDPTLVRDILR 472
             +    +   +   T+    Q L  IR EFG  +      ++   D++R      DI  
Sbjct: 401 YQESFNTLSGFR-AATESEHGQHL--IREEFGPGEIAPSTVVVHSQDNLRSSPAPADIA- 456

Query: 473 FEREIKADSYINNVFETQSIADVVIQKYGYIPQDKEKISEAIEGSSLVSSDYSMTIIKLK 532
                   + + +      +AD  + K G     K    + I    L    YS   +   
Sbjct: 457 --------TALTDADHVSRVADPRMGKDG-----KTVFYDVI----LDLDPYSSKALDAI 499

Query: 533 GNFMGVTQSEFNRIMEYFERAIQRADFPPGVKVELAGESYLNYVLNDLVNEELGKISTIG 592
           G     TQS           A Q A       V + GE+  N  +   ++ +   I  + 
Sbjct: 500 GPLKQATQS-----------AAQAAGVQDAT-VLIGGETAQNADIRSALDRDTTLIVLLV 547

Query: 593 TLIVVMVVFAIFR---RPTVSIAMIMPMFLGAL-----WTIGYMGLAGIPFSQTLAGVVS 644
             IV +V+  + R    P   +A ++  FL  L     +T+  +G  GI  ++  A +  
Sbjct: 548 LAIVTVVLVLLLRSLLAPLYLVATLLLSFLATLGATTFFTVTVLGDDGIG-NRVTAYIFV 606

Query: 645 MIVGLGVDYGMHITHRFLEELNEGNKTPIIT-ALESVGPGIFVGALTTAGGFLALLSAQL 703
            +V LGVDY + I  RF +EL        IT AL   G  I    L  A  F  L++  +
Sbjct: 607 FLVALGVDYNIFIMSRFKQELRTQPPAKAITAALTRTGGVISSAGLILAATFAVLMTQPI 666

Query: 704 TAIHDFGRVLAVGIFASMFAAY-LVTPAILQL 734
             +  FG  +A GI    F    L+ PAI++L
Sbjct: 667 RELFQFGFAMACGILLDTFLIRPLLVPAIVRL 698


>pir||D72329 hypothetical protein - Thermotoga maritima (strain MSB8)
           >gi|4981348|gb|AAD35899.1|AE001749_2 (AE001749)
           hypothetical protein [Thermotoga maritima]
           Length = 674
           
 Score =  102 bits (253), Expect = 1e-20
 Identities = 85/356 (23%), Positives = 170/356 (46%), Gaps = 43/356 (12%)

Query: 3   RKIARVIVIYRHSLAVVTMFLLILSAYGITQLRFETDLSKQLPEDLEAVKSYFTLQNEFG 62
           RKIA +++       VV + +  LS + + +++  +D+      D E  K+Y  +  +F 
Sbjct: 353 RKIALIVL-------VVFLVMAALSPFLLKRVQVGSDMVSYFERDSELRKAYDLIVKKFN 405

Query: 63  GSGSALIYVKIKNNDNVVDIRDPKIIEAMYSLEQRLREKEYVTDTFSIADLMVQILGRLP 122
                 IY+ ++ N   V   D KI++    L +++ + EYV+      D+ V I+  L 
Sbjct: 406 TREP--IYLVLEKNVPFVGT-DSKILK---ELIEKIEKSEYVSSVVFPVDIPVPIMYTLS 459

Query: 123 KNMDEVKFVLNMLPPEARNGLISGDYSSTIIIVNLNRE--KNQKALVRVYNDIEREIERT 180
           +    +K  +             GD +   +IVNL  E  ++ K +V + N++  E   +
Sbjct: 460 RTNPFLKTFV-------------GDRNRIRLIVNLTPEGYEHVKKVVDLINEVVSETGWS 506

Query: 181 NFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPLVPL 240
           ++  G  V++  D+       E +     +++ ++ I++  ++   ++ P+  L  ++P+
Sbjct: 507 HYVAG-SVLIWNDIN------ESIMRSQIQSIVLASILIFAMVFIIFRRPLTTLSVMIPI 559

Query: 241 IFGVVMTLGFMGLLGIPLDIATTTVGAMIIGMGIDYGVHVTNRYYEERGKGKSLEEAAEE 300
            F  V    FM L GI LD++T+    +++G+ IDY +H+ +   E R +   L      
Sbjct: 560 AFTTVFNFLFMALFGISLDVSTSITSGILMGLVIDYSIHIASE--ERRLRDPYL------ 611

Query: 301 AIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVTPAL 356
            +   G ++L  AL  I+GF  L  S L   K +S+ +++G+G+ A+  +IV P +
Sbjct: 612 VVKNVGPSVLTNALGLISGFAVLLFSELALFKNISLLMMLGIGVGAIFTLIVQPMI 667


>gb|AAD44231.1|AF143772_37 (AF143772) TmtpB [Mycobacterium avium]
           Length = 963
           
 Score =  101 bits (249), Expect = 3e-20
 Identities = 94/375 (25%), Positives = 156/375 (41%), Gaps = 33/375 (8%)

Query: 106 DTFSIADLMVQILGRLPKNMDEVKFVLNMLPPEARNGLISGDYSSTIIIVNLNREKNQKA 165
           D  +  D ++++L    K++  V+       P  R    S D  +  + VNLN      A
Sbjct: 96  DAHTYYDRLIRLLENDHKHVQHVQNFWG--DPLTRGAAQSQDGKAAYVQVNLNGNAGAAA 153

Query: 166 LVRVYNDIEREIERTNFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLY 225
                  I + ++  + P G++V +TG   I   +    Q  +      S I++ + LL 
Sbjct: 154 GDESVAAIRKLVQEASPPPGLKVYVTGPAPIVADMNIAGQKTVMLVTLASLIVIFVTLLL 213

Query: 226 FYKSPIRMLVPLV------PLIFGVVMTLGFMGLLGIPLDIATTTVGAMIIGMGIDYGVH 279
            Y+S I +++ L+       +  G+V  LG +G++G+    A   + A +I  G DYG+ 
Sbjct: 214 VYRSVITVILLLLIVGLELQIARGMVALLGHLGVVGLTT-FAVNLLVAAVIATGTDYGIF 272

Query: 280 VTNRYYEERGKGKSLEEAAEEAIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLV 339
              RY E R  G+S EEA         K +L + LT     L LS + LP  + L + + 
Sbjct: 273 FVGRYQEARQAGESREEAFYTTFNGVAKVVLASGLTIAGAVLCLSFTRLPYFQPLGIPVA 332

Query: 340 MGLGLAALNAVIVTPALAILEEEF-----REKVMKKKEIIAIGGGKSKISFIFSMLGKAI 394
           +G+ +A L A+ + PAL      F     R  V  ++               +  +G AI
Sbjct: 333 VGISIAVLVALTLGPALLAAGARFGLFEPRRAVSARR---------------WRRIGTAI 377

Query: 395 KRSPWTALLIALIISGVSLYGASKITTEVRLEKMIPTDLPEIQALSDIRSEFGGQ----D 450
            R P   L+  L +S V L            +K IP  +P     +     F GQ     
Sbjct: 378 VRWPAPILIATLAVSLVGLLALPNYRPSYDDQKFIPDSIPANVGFAAAARHFPGQRMQMP 437

Query: 451 EVTILIKADDVRDPT 465
           E+ ++    D+R+PT
Sbjct: 438 EILLVETDHDLRNPT 452


>sp|O53784|MML5_MYCTU PUTATIVE MEMBRANE PROTEIN MMPL5 >gi|7478343|pir||E70826 probable
           membrane protein - Mycobacterium tuberculosis  (strain
           H37RV) >gi|2909649|emb|CAA17459.1| (AL021943) mmpL5
           [Mycobacterium tuberculosis]
           Length = 964
           
 Score =  101 bits (248), Expect = 4e-20
 Identities = 90/386 (23%), Positives = 160/386 (41%), Gaps = 21/386 (5%)

Query: 116 QILGRLPKNMDEVKFVLNML-PPEARNGLISGDYSSTIIIVNLNREKNQKALVRVYNDIE 174
           Q++GRL  +   V+ + +    P    G  S D  +  + V L   + +         ++
Sbjct: 111 QMIGRLQADTTHVQSLQDFWGDPLTATGAQSSDGKAAYVQVKLAGNQGESLANESVEAVK 170

Query: 175 REIERTNFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRML 234
             +ER   P GV+V +TG   +     +     +    A++  +++++LL  Y+S I   
Sbjct: 171 TIVERLAPPPGVKVYVTGSAALVADQQQAGDRSLQVIEAVTFTVIIVMLLLVYRSIITSA 230

Query: 235 VPLVPLIFGVVMTLGFMGLLGIPLDI-----ATTTVGAMIIGMGIDYGVHVTNRYYEERG 289
           + L  ++ G++ T G +  LG    I     AT  +  + I    DY + +  RY E RG
Sbjct: 231 IMLTMVVLGLLATRGGVAFLGFHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRYQEARG 290

Query: 290 KGKSLEEAAEEAIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNA 349
            G+  E A       T   +LG+ LT       LS + LP  + L V L +G+ +    A
Sbjct: 291 LGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQTLGVPLAIGMVIVVAAA 350

Query: 350 VIVTPALAILEEEFREKVMKKKEIIAIGGGKSKISFIFSMLGKAIKRSPWTALLIALIIS 409
           + + PA+  +   F  K+++ K +  + G +         +G AI R P   L+ A+ ++
Sbjct: 351 LTLGPAIIAVTSRF-GKLLEPKRMARVRGWRK--------VGAAIVRWPGPILVGAVALA 401

Query: 410 GVSLYGASKITTEVRLEKMIPTDLPEIQALSDIRSEFGG---QDEVTILIKADDVRDPTL 466
            V L       T       +P DLP  +  +     F       EV ++    D+R+   
Sbjct: 402 LVGLLTLPGYRTNYNDRNYLPADLPANEGYAAAERHFSQARMNPEVLMVESDHDMRNSA- 460

Query: 467 VRDILRFEREIKADSYINNVFETQSI 492
             D L   +  KA   +  +   Q+I
Sbjct: 461 --DFLVINKIAKAIFAVEGISRVQAI 484


>emb|CAB90894.1| (AL355753) putative integral membrane protein. [Streptomyces
           coelicolor A3(2)]
           Length = 739
           
 Score = 97.1 bits (238), Expect = 6e-19
 Identities = 125/560 (22%), Positives = 229/560 (40%), Gaps = 69/560 (12%)

Query: 205 QNDMNRTMAISGI-IVVLILLYFYKSPIRMLVPLVPLIFGVVMTLGFMGLLGIPLDI-AT 262
           + +M  T  + GI +  ++LL  + S +   +PL+  I GV + +  +G LG  L++ AT
Sbjct: 171 EQEMGGTAELIGIGVAAIVLLLTFGSLVAAGMPLLSAIIGVGIGISAIGALGSTLELSAT 230

Query: 263 TTVGAMIIGMG--IDYGVHVTNRYYEERGKGKSLEEAAEEAIAETGKALLGAALTTIAGF 320
           T+  AM+IG+   IDY + + +RY  E  +G++ EEAA  A+   G A++ A LT +   
Sbjct: 231 TSTLAMMIGLAVAIDYALFIVSRYRAEISEGRAPEEAAGRAVGTAGSAVVFAGLTVVVAL 290

Query: 321 LALSISILPSLKRLSVSLVMGLGLAALNAVIVTPALAIL--EEEFREKVMKKKEIIAIGG 378
             L+I  +P L ++ ++    +G+A L A+ +TPAL     +     K  K         
Sbjct: 291 AGLAIVNIPILTKMGLAAAGTVGIAVLIALTLTPALLGFAGKRALSRKDRKAPAGARAAS 350

Query: 379 GKSKISFIFSMLGKAIKRSPWTALLIALIISGVSLYGASKITTEVRLEKMIPTDLPEIQA 438
           GK K+    +   + ++R P T LL A++  GV    A+ +   +  E     D  + +A
Sbjct: 351 GKPKLG---TRWARFVQRRPVTVLLTAVLGLGVIAVPAAGMELGLPDEGSSAPDTTQRKA 407

Query: 439 LSDIRSEFGG--QDEVTILIKADDVRDPTLVRDILRFEREIKADSYINNVFETQSIADVV 496
              +   FG      + + + A    DP    D +           I  + E  ++    
Sbjct: 408 YDMLSESFGAGFNGPLMVTVDARGADDPKAAADTV--------GEKITGLGEAAAVTPAN 459

Query: 497 IQKYGYIPQDKEKISEAIEGSSLVSSDYSMTIIKLKGNFMGVTQSEFNRIMEYFERAIQR 556
             +               EG + V     +T++   G     T+S  + I         R
Sbjct: 460 FNE---------------EGDTAV-----LTVMPKTGPSDVATESLVHDIRSL--SGDIR 497

Query: 557 ADFPPGVKVELAGESYLNY--VLNDLVNEELGKISTIGTLIVVMVVFAIF--RRPTVSIA 612
           AD    + V  A    +++   L+D +   L  +  +  L++++V  ++    +  +   
Sbjct: 498 ADTGAAMLVTGATAMTIDFSQTLDDALIPYLALVVGLAFLLLMLVFRSVLVPLKAALGFL 557

Query: 613 MIMPMFLGALWTIGYMGLAGIPFSQTLAG---------VVSMIVGLGVDYGMHITHRFLE 663
           + +   LGA+  +   G     F     G         ++ ++ GL +DY + +  R  E
Sbjct: 558 LSVAAALGAVVAVFQWGWLADVFGVDQPGPIMSMMPIFMIGVVFGLAMDYEVFLVTRMRE 617

Query: 664 ELNEGNKTPIITALESVGPGIFVGALTTAGGFLALLSA---------QLTAIHDFGRVLA 714
               G      +A ESV  G   G    A   + ++S           +  +  FG  +A
Sbjct: 618 AYVHGE-----SAAESVTTGFTHGGRVVAAAAIIMISVFSGFILENDAMIKMMGFGLAIA 672

Query: 715 VGIFASMFAAYLVTPAILQL 734
           V +F +      + PA+L L
Sbjct: 673 V-LFDAFVVRMAIVPAVLAL 691


>pir||B81282 probable integral membrane protein Cj1373 [imported] -
           Campylobacter jejuni (strain NCTC 11168)
           >gi|6968807|emb|CAB73800.1| (AL139078) putative integral
           membrane protein [Campylobacter jejuni]
           Length = 823
           
 Score = 94.4 bits (231), Expect = 4e-18
 Identities = 151/832 (18%), Positives = 335/832 (40%), Gaps = 116/832 (13%)

Query: 1   MLRKIARVIVIYRHSLAVVTMFLLILSAYGITQLRFETDLSKQLPEDLEAVKSYFTLQNE 60
           M  K+ +  +    S    T+F+ +  ++   +L  +      L ED   +K++  +   
Sbjct: 1   MFAKLLKFFISRPKSTFFGTLFICLFLSFFAFKLSVDASAESLLLEDDADLKTFREISKH 60

Query: 61  FGGSGSALIYVKIKN-----NDNVV-------DIRDPKIIEAMYSL-EQRLREKEYVTDT 107
           +      L+  K  +     N+N+        ++    ++E ++S+    L +    TD 
Sbjct: 61  YKSDNFLLLAFKPYDEKPFSNENLAKLKKLHEELEKAPLVERVFSIINAPLLQSSQNTD- 119

Query: 108 FSIADLMVQILGRLPKNMDEVKFVLNML-PPEARNGLISGDYSSTIIIVNLN-------- 158
             + +L+  I     ++++  K    +L  P  +N +IS D   T +I+ L         
Sbjct: 120 --LKELLKNIPNIESQDINRTKAQNEILNSPFYKNNIISKDGKVTGLIIYLKPDTVYNNL 177

Query: 159 ----------REKNQKAL-VRVYNDIEREIERT----------NFPQGVEVVLTGDLG-I 196
                     +EK+Q  L ++ + D ++ I +           N+ +  + +  G +  I
Sbjct: 178 IEKRDLATDEKEKDQIRLAIKEHQDKQKVITKQSLDTIKSIVRNYEKNKDTLYLGGVSMI 237

Query: 197 TYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPLVPLIFGVVMTLGFMGLLGI 256
              ++  +++D+         ++ L L YF++S   + +PL      +    G   LL  
Sbjct: 238 ADDMIAYIKSDLVLYGVSLVFLLGLALYYFFRSWRFVFLPLFICFISLSAASGVFALLNF 297

Query: 257 PLDIATTTVGAMIIGMGIDYGVHVTNRYYE--ERGKGKSLEEAAEEAIAETGKALLGAAL 314
            + + ++   A+++ + +   VH+   + E  +      +E    E +       L A +
Sbjct: 298 QITVISSNYVALVLIITLSVVVHLITHFIESTQNHPKAKVERIVLETLLAKANPSLYAIV 357

Query: 315 TTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVTPALAIL-------EEEFREKV 367
           TT+ GF +L +S +  + +L + + +G+GLA + + +   ++ +L       ++EF+  +
Sbjct: 358 TTMIGFFSLILSNIEPIIKLGIMMSIGIGLALIFSYLFLASILVLLKPKNYHKKEFKFNL 417

Query: 368 MKKKEIIAIGGGKSKISFIFSMLGKAIKRSPWTALLIALIISGVSLYGASKITTEVRLEK 427
           +      A+   K ++ +  S+L          A+++ALI       G SK+  E     
Sbjct: 418 LAFCAKTALDPKKRRMIYEISVL----------AIILALI-------GISKLRVENSFVN 460

Query: 428 MIPTDLPEIQALSDIRSEFGGQDEVTILIKADDVRDPTLVRDIL-RFEREIKADSYINNV 486
                    + L  I    GG   + ++I+  + ++     D L  FE E + +      
Sbjct: 461 YFKDGSEIKKGLLVIDKNLGGTLPLEVIIRFPNNKNDQNASDTLDSFESEFE-NLATQET 519

Query: 487 FETQSIADVVIQKYGYIPQDKEKISEAIEGSSLVS-----------SDYSMTIIK----- 530
           +   S    + +K     ++KE +   +  +SL++            D+++  +      
Sbjct: 520 YWFDSKKTRIAKKVHEFLENKEFVGSVLSLNSLLTLGKNINDGKELDDFALAFLNENLPA 579

Query: 531 -----LKGNFMGVTQSEFNRIMEYFER--AIQRADF-------------PPGVKVELAGE 570
                L   F+ +  +E    M   +    ++R +F               GV+V++ G 
Sbjct: 580 KFKQDLLSPFVSIENNELRFSMRIVDSDPNLRRNEFLIDLKKQLNELVKNDGVEVQITGI 639

Query: 571 SYL-NYVLNDLVNEELGKISTIGTLIVVMVVFAI-FRRPTVSIAMIMPMFLGALWTIGYM 628
             L N +L  L + +   +  I  ++ + ++F I FR    S+A I+   +        M
Sbjct: 640 MVLYNNMLQSLFSSQFDTL--IFVILAIFILFIIVFRDLKFSVAAILVNVIPLSVVFALM 697

Query: 629 GLAGIPFSQTLAGVVSMIVGLGVDYGMHITHRFLEEL-NEGNKTPIITALESVGPGIFVG 687
           GL GIP       + ++ +G+GVD  +H  +RF EE+ N+  +  I+ +  S+G  ++  
Sbjct: 698 GLLGIPLDMMSITIAAIAIGIGVDDAIHYIYRFREEIKNKSLEEAIMISHLSIGSALYYT 757

Query: 688 ALTTAGGFLALLSAQLTAIHDFGRVLAVGIFASMFAAYLVTPAILQLEFGRK 739
            ++   GF  ++S+       FG +    +   +  +  + P+ L   + +K
Sbjct: 758 TISIVLGFSVMMSSNFIPTIYFGILTVFVMILLLSGSLFLLPSFLITIYSKK 809


 Score = 92.4 bits (226), Expect = 2e-17
 Identities = 87/362 (24%), Positives = 160/362 (44%), Gaps = 58/362 (16%)

Query: 13  RHSLAVVTMFLLILSAYGITQLRFETDLSKQLPEDLEAVKSYFTLQNEFGGSGSALIYVK 72
           R  +  +++  +IL+  GI++LR E        +  E  K    +    GG+    + ++
Sbjct: 431 RRMIYEISVLAIILALIGISKLRVENSFVNYFKDGSEIKKGLLVIDKNLGGTLPLEVIIR 490

Query: 73  IKNNDNVVDIRDP---------------------KIIEAMYSLEQRLREKEYVTDTFSIA 111
             NN N  +  D                      K       + + L  KE+V    S+ 
Sbjct: 491 FPNNKNDQNASDTLDSFESEFENLATQETYWFDSKKTRIAKKVHEFLENKEFVGSVLSLN 550

Query: 112 DLMVQILGRLPKNMDEVK--------FVLNMLPPEARNGLISG---------DYSSTIII 154
            L+      L KN+++ K        F+   LP + +  L+S           +S  I+ 
Sbjct: 551 SLLT-----LGKNINDGKELDDFALAFLNENLPAKFKQDLLSPFVSIENNELRFSMRIVD 605

Query: 155 VNLNREKNQKALVRVYNDIEREIERTNFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAI 214
            + N  +N+  +     D+++++       GVEV +TG + +   +L+ L +    T+  
Sbjct: 606 SDPNLRRNEFLI-----DLKKQLNELVKNDGVEVQITGIMVLYNNMLQSLFSSQFDTLIF 660

Query: 215 SGIIVVLILLYFYK----SPIRMLVPLVPLIFGVVMTLGFMGLLGIPLDIATTTVGAMII 270
             + + ++ +  ++    S   +LV ++PL   VV  L  MGLLGIPLD+ + T+ A+ I
Sbjct: 661 VILAIFILFIIVFRDLKFSVAAILVNVIPL--SVVFAL--MGLLGIPLDMMSITIAAIAI 716

Query: 271 GMGIDYGVHVTNRYYEERGKGKSLEEAAEEAIAETGKALLGAALTTIAGF-LALSISILP 329
           G+G+D  +H   R+ EE  K KSLEEA   +    G AL    ++ + GF + +S + +P
Sbjct: 717 GIGVDDAIHYIYRFREEI-KNKSLEEAIMISHLSIGSALYYTTISIVLGFSVMMSSNFIP 775

Query: 330 SL 331
           ++
Sbjct: 776 TI 777


>emb|CAB89762.1| (AL354616) putative integral membrane protein. [Streptomyces
           coelicolor A3(2)]
           Length = 748
           
 Score = 94.0 bits (230), Expect = 5e-18
 Identities = 116/549 (21%), Positives = 219/549 (39%), Gaps = 57/549 (10%)

Query: 213 AISGIIVVLILLYFYKSPIRMLVPLVPLIFGVVMTLGFMGLLG--IPLDIATTTVGAMI- 269
           AI   +  ++LL  + S     +PL+  + GV +++  +  LG  + L + T T+ +M+ 
Sbjct: 181 AIGIALAAVVLLITFGSLAAAGLPLLTAVIGVGVSMCAILALGSTLGLTMTTGTLASMLG 240

Query: 270 IGMGIDYGVHVTNRYYEERGKGKSLEEAAEEAIAETGKALLGAALTTIAGFLALSISILP 329
           + +GIDY + V +RY EER  G +  EAA  A+   G A++ A LT I   + L++  +P
Sbjct: 241 LAVGIDYALFVVSRYREERANGHAPREAAGLAVGTAGSAVVFAGLTVIIALVGLTVIGVP 300

Query: 330 SLKRLSVSLVMGLGLAALNAVIVTPALAIL--EEEFREKVMKKKEIIAIGGGKSKISFIF 387
            L ++ +     + +A L A+ + PAL  +        +V K +E     G     S   
Sbjct: 301 MLTKMGLCAAGAVAIAVLVALTLVPALLGMWPNAVLSRRVRKFREADKRDGNAKHHSETP 360

Query: 388 SMLG----KAIKRSPWTALLIALIISGVSLYGASKITTEVRLEKMIPTDLPEIQALSDIR 443
              G    + + R P   LL+ + + GV    A+ +   +  ++  PT   E +A   + 
Sbjct: 361 DNGGTRWARFVMRRPVAVLLLGVAVLGVLALPATHLEMGMPGDEAKPTSTTERRAYDALA 420

Query: 444 SEFGGQDEVTILIKADDVRDPTLVRDILRFEREIKADSYINNVFETQSIADVVIQKYGYI 503
             FG      + + A DV+D T        + +  A +    + +T  +  V        
Sbjct: 421 DGFGAGFNGPLTVVA-DVKDAT--------DPQAAAATMAEQIKDTDGVVSVT------P 465

Query: 504 PQDKEKISEAIEGSSLVSSDYSMTIIKLKGNFMGVTQSEFNRIMEYFERAIQRADFPPGV 563
           PQ  E       G + + S    T         G        I++         +   G 
Sbjct: 466 PQFNE------AGDTALFSAVPAT---------GPNTEATKEIVQTIRAERPGLEADTGA 510

Query: 564 KVELAGESYLNYVLNDLVNEELGKISTIGTLIVVMVVFAIFRRPTVSIAMIMPMFLGALW 623
             E+ G + +N  +   + + L     +  L+ ++++  +FR   V +   +   L  L 
Sbjct: 511 TFEVTGSTAMNIDVAQALQDALVPYLAVIVLLSLLLLLIVFRSILVPVKAALGFLLSVLA 570

Query: 624 TIGYM----------GLAGIPFSQTLAG-----VVSMIVGLGVDYGMHITHRFLEELNEG 668
           ++G +          GL G+  +  +       +V ++ GL +DY + +  R  E    G
Sbjct: 571 SLGTVVAVFQWGWGAGLLGVEQTGPIMSLMPIFLVGIVFGLAMDYEVFLVARMREAYVHG 630

Query: 669 NK--TPIITALESVGPGIFVGALTTAGGFLALLSAQLTAIHDFGRVLAVGIFASMFAAYL 726
            +    ++T        +   A+     F   + +  + I   G  LAV +    F   +
Sbjct: 631 ERPGQAVVTGFRHSARVVAAAAVIMMAVFSGFIGSGESMIKTIGFGLAVAVLFDAFVVRM 690

Query: 727 -VTPAILQL 734
            + PA+L L
Sbjct: 691 ALVPAVLAL 699


>emb|CAB89749.1| (AL354616) putative membrane protein [Streptomyces coelicolor
           A3(2)]
           Length = 716
           
 Score = 92.1 bits (225), Expect = 2e-17
 Identities = 125/578 (21%), Positives = 236/578 (40%), Gaps = 73/578 (12%)

Query: 183 PQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPLVPLIF 242
           P G+E+ +TG   I   +  +      + +  +  +V L+L+  Y+SP+  ++PLV +  
Sbjct: 162 PSGLELEVTGPGAIDGDMDAVFDGIDEQVLLTTIAVVTLLLILTYRSPVLWIIPLVAVGA 221

Query: 243 GVVMTLGFMGLL----GIPL-DIATTTVGAMIIGMGIDYGVHVTNRYYEERGKGKSLEEA 297
             + ++G + LL    GI + D  +  +  ++ G+G DY + +  RY E     +++  A
Sbjct: 222 AALTSMGTVYLLVKGFGIVVNDQNSALLTILVFGVGTDYALLLIARYREALHHQENVRGA 281

Query: 298 AEEAIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVTPALA 357
              A+     A++ +A T ++G L L ++ L S   L      G+  A +  + + PA+ 
Sbjct: 282 MVHALRGAAPAIVASAATVVSGLLCLLVADLNSTSGLGPIGAAGILCALVAMLTLFPAVL 341

Query: 358 IL--EEEFREKVMKKKEIIAIGGGKSKISFIFSMLGKAIKRSPWTALLIALIISGVSLYG 415
           ++     F   V +    +    G      ++  LG AI R  W A L +  + GV   G
Sbjct: 342 VVLGRRIFWPAVPRFSTAVEEKPG------LWGRLGTAINRRRWVATLGSFGVLGVLALG 395

Query: 416 ASKITTEVRLEKM---IPTDLPEIQALSDIRSEFGGQDEVTILIKADDVRDPTLVRDILR 472
            +  TT +R +     +P  +     L +   E GGQ              P  V     
Sbjct: 396 LAGNTTALREQDQFLSVPESVTGFTVLREHFPELGGQ--------------PLTV----- 436

Query: 473 FEREIKADSYINNVFETQSIADVVIQKYGYIPQDKEKISEAIEGSSLVSSDYSMTIIKLK 532
           F R  + +  ++ V +T+ +A  V +             E + G + +S         + 
Sbjct: 437 FTRPAQQEKVLDVVEDTRGVALAVPE-------------ETVGGWANIS---------VF 474

Query: 533 GNFMGVTQSEFNRIMEYFERAIQRADFPPGVKVELAGESYLNYVLNDLVNEELGKISTIG 592
                 T +E++ I    +R         G +  + G S  N +  ++      K+    
Sbjct: 475 PKDAPDTAAEYDTI----KRVRTAVHMVSGAEAIVGGPSAEN-LDTEVTTRRDEKLVIPL 529

Query: 593 TLIVVMVVFAIFRR----PTVSIAMIMPMFLGALWTIGY-----MGLAGIPFSQTLAGVV 643
            L+VV+++  +  R    P V +A ++  F  A     +     +G  G+ +S  L   +
Sbjct: 530 VLVVVLIILGLLLRAVLAPLVLMATVVVSFAAAFGGSVFVFDTILGFKGVDYSVPLLAFL 589

Query: 644 SMIVGLGVDYGMHITHRFLEE-LNEGNKTPIITALESVGPGIFVGALTTAGGFLALLSAQ 702
             +V LGVDY + +  R  +E +  G +  ++ AL + G  I    L  A  F  L++  
Sbjct: 590 -FLVALGVDYNIFLASRARQETMRLGAREGMLKALSATGGVITSAGLVLAATFGVLVTLP 648

Query: 703 LTAIHDFGRVLAVGIFASMFAAYLVTPAILQLEFGRKI 740
           L  + + G ++A G+         V    L L  GR++
Sbjct: 649 LVMLVEVGFLVAFGVLLDALLVRSVLVPALTLLIGRRM 686


>dbj|BAB04439.1| (AP001509) unknown conserved protein in others [Bacillus
           halodurans]
           Length = 687
           
 Score = 89.3 bits (218), Expect = 1e-16
 Identities = 153/749 (20%), Positives = 304/749 (40%), Gaps = 89/749 (11%)

Query: 5   IARVIVIYRHSLAVVTMFLLILSAYGITQLRFETDLSKQLPEDLEAVKSYFTLQNEFGGS 64
           IA  I+  R ++ +    L  +SA  +  +    +++  LP++ ++ K+   L+ EF  +
Sbjct: 4   IAAFIIKKRKTIVLSFAILTFISAIALFFVSVNYNMTDYLPDEAQSTKAIEVLEEEFDRT 63

Query: 65  GSALIYVKIKNNDNVVDIRDPKIIEAMYSLEQRLREKEYVTDTFSIADLMVQILGRLPKN 124
            S         N  V+ IRD  + EA+   ++ L E + V+D   + +++          
Sbjct: 64  VS---------NARVM-IRDVTVQEALL-YKKELEEIDGVSDVIWLDEVI---------- 102

Query: 125 MDEVKFVLNMLPPEARNGLISGDYSSTIIIVNLN-REKNQKALVRVYNDIEREIERTNFP 183
             +++  L M    A   L+   Y     + +L  RE ++ A+     ++          
Sbjct: 103 --DLETPLEM----ADKDLVKSYYKDESALFSLTIREGDEVAVTDAIYELI--------- 147

Query: 184 QGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPLVPLIFG 243
            G +  L+G+   T    +M   +     ++   I+V+IL+    S I  L  L  +   
Sbjct: 148 -GEDNALSGEAVNTAVSQQMTGKETIYAASLLIPIIVIILIISTTSWIEPLFFLTAIGVS 206

Query: 244 VVMTLGFMGLLGIPLDIATTTVGAMIIGMGIDYGVHVTNRYYEERGKGKSLEEAAEEAIA 303
           V++ LG    +G    +  +    + + + +DY + + +R+ + R + +  EEA + A+ 
Sbjct: 207 VLINLGTNIFIGEVSFVTQSVSPILQLAVSLDYAIFLLHRFSDYRKQTEDPEEAMQIAVR 266

Query: 304 ETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVTPALAILEEEF 363
           ++  A+  +A TT  GF AL+         L ++LV G+ L+ ++ ++  PAL I   ++
Sbjct: 267 KSFPAIAASAATTFFGFTALTFMQFEIGADLGLNLVKGIVLSFISVMVFLPALTICFYKW 326

Query: 364 REKVMKK---KEIIAIGGGKSKISFIFSMLGKAIKRSPWTALLIALIISGVSLYGASKIT 420
            +K   +       +IG G  KI FI             +  +++L+I  V  Y A   T
Sbjct: 327 IDKTQHRPFFPRFQSIGNGVMKIRFI-------------SLAVVSLLI--VPSYLAQGQT 371

Query: 421 TEVRLEKMIPTDLPEIQALSDIRSEFGGQDEVTILIKADDVRDPTLVRDILRFEREIKAD 480
           + +     +P         + I   FG    + +L+   DV      R++   E+E++  
Sbjct: 372 SFIYGIGELPESSRAGSDTATIEEVFGKSTPIVLLVPKGDV-----AREV-EMEQELEKV 425

Query: 481 SYINNVFE-TQSIADVVIQKYGYIPQDKEKISEAIEGSSLVSSDYSMTIIKLKGNFMGVT 539
            YI NV    QS++  +  +Y         I E++      S  YS  I+  +      T
Sbjct: 426 DYITNVISYNQSVSATIPSEY---------IDESVT-EQFYSEHYSQIILYTE------T 469

Query: 540 QSEFNRIMEYFERAIQRADFPPGVKVELAGESYLNYVLNDLVNEELGKISTIGTLIVVMV 599
             E        E   + A    G      GES   Y +   + ++   ++ +  + + +V
Sbjct: 470 DVEGEVAFSVVETVQEIAASYYGDDALSLGESVSLYDMKTTIMKDNRVVNLLTVVAIAIV 529

Query: 600 VFAIFRRPTVSIAMIMPMFLGALW---TIGYMGLAGIPF-SQTLAGVVSMIVGLGVDYGM 655
           +   FR  ++ + +++ +   A+W    + Y   A + +    + G V +     VDY +
Sbjct: 530 LLLTFRSISIPVILLLTI-QSAVWLNLAVPYFTDAPLVYLGYLIVGTVQL--AATVDYAI 586

Query: 656 HITHRFLEELNEGNKTPII--TALESVGPGIFVGALTTAGGFLALLSAQLTAIHDFGRVL 713
             T  +L    +  +   I  T  E         A+ ++ GF+  L++    +   G +L
Sbjct: 587 LYTEGYLVNRRKMPRRQAITKTLTEKTFSISISAAILSSVGFILWLTSSNPVVSSIGLLL 646

Query: 714 AVGIFASMFAAYLVTPAILQLEFGRKISK 742
             G   +        PA+L L F + I K
Sbjct: 647 GRGALLAFILVIFFLPAML-LVFDKAIRK 674


>emb|CAB59662.1| (AL132674) putative membrane transport protein [Streptomyces
           coelicolor A3(2)]
           Length = 745
           
 Score = 87.4 bits (213), Expect = 5e-16
 Identities = 149/772 (19%), Positives = 290/772 (37%), Gaps = 106/772 (13%)

Query: 2   LRKIARVIVIYRHSLAVVTMFLLILSAYGITQLRFETDLSKQLPEDLEAVKSYFTLQNEF 61
           L K+ R+    RH +A++ + LL L+  G        + S  +P   EA K++  L+  F
Sbjct: 5   LYKLGRLAFRRRHFVALIWVALLTLAGVGAASAPPAGNSSFSIP-GTEAQKAFDLLEQRF 63

Query: 62  GGSGS----ALIYVKIKNNDNVVDIRDPKIIEAMYSLEQRLREKEYVTDTFSIADLMVQI 117
            G+ +    A +  K    + + D  +   +E      + + E    ++  S+AD     
Sbjct: 64  PGASADGATARVVFKAPAGETMTDAGNKATVE------KTVDELADGSEVASVAD----- 112

Query: 118 LGRLPKNMDEVKFVLNMLPPEARNGLISGDYSSTIIIVNLNREKNQKALVRVYNDIEREI 177
                              P   N  +S D   TI   ++  + +   L     D   + 
Sbjct: 113 -------------------PYTGNA-VSED--GTIAYASVKYDVSGMELEESTKDALEDA 150

Query: 178 ERTNFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPL 237
            +     G+ V + GD       L+ +  +   T  I   +  ++L+  + S +   +PL
Sbjct: 151 AQQARDAGLTVEIGGDA------LQAVP-ETGATEVIGIAVAAVVLVITFGSLVSAGLPL 203

Query: 238 VPLIFGVVMTLGFMGLLGIPLDI-ATTTVGAMIIGM--GIDYGVHVTNRYYEERGKGKSL 294
           +  + GV + +  +  L   L++ +TT++ AM+IG+  GIDY + + +RY  E  +G+  
Sbjct: 204 LTALIGVGIGVSSITALASALELGSTTSILAMMIGLAVGIDYALFIVSRYRAELAEGRER 263

Query: 295 EEAAEEAIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVTP 354
           EEAA  A+   G A++ A LT +   + L++  +P L ++ ++    + +A L A+ + P
Sbjct: 264 EEAAGRAVGTAGSAVVFAGLTVVIALVGLAVVNIPMLTKMGIAAAGTVAIAVLIALTMIP 323

Query: 355 A-LAILEEEFREKVMKKKEIIAIGGGKSK--------ISFIFSMLGKAIKRSPWTALLIA 405
           A L       +    K K +     G+ K         + + +     + R P   LL+ 
Sbjct: 324 ALLGYAGRRVKPAGAKGKRLGRSRKGEPKPDRPAGQPKANLGTRWASFVVRRPLAVLLLG 383

Query: 406 LIISGVSLYGASKITTEVRLEKMIPTDLPEIQALSDIRSEFGGQDEVTILIKADDVRDPT 465
           +I  G +   A+ +   +  +   PT   + +A   +   FG      +++  D      
Sbjct: 384 VIGLGAAAVPAASLELGLPDDGSQPTSTTQRRAYDLLSEGFGPGFNGPLMVVVDAKGSDA 443

Query: 466 LVRDILRFEREIKADSYINNVFETQSIADVVIQKYGYIPQDKEKISEAIEGSSLVSSDYS 525
                   E+ IK    +  V                +P  K         SS+ + D  
Sbjct: 444 PKDAFTDVEQRIKGLDGVVAVAPPAPNKGGDTATITVVPDSKP--------SSVQTEDLV 495

Query: 526 MTIIKLKGNFMGVTQSEFNRIMEYFERAIQRADFPPGVKVELAGESYLNYVLNDLVNEEL 585
             I    G+    T                      G +  + G + +N  ++  +N+ L
Sbjct: 496 HAIRDAGGDVEAKT----------------------GAETLVTGATAMNIDVSQKLNDAL 533

Query: 586 GKISTIGTLIVVMVVFAIFRRPTVSIAMIMPMFLGAL-------------WTIGYMGL-- 630
                +   +  +++  +FR   V +   +   L  +             W  G MG+  
Sbjct: 534 VPYLVLVVGLAFLLLIVVFRSILVPLKAALGFLLSVMAALGAVVAVFQWGWLSGLMGVEE 593

Query: 631 AGIPFSQTLAGVVSMIVGLGVDYGMHITHRFLEELNEGNK--TPIITALESVGPGIFVGA 688
            G   S     +V ++ GL +DY + +  R  E    G K    ++T  +     +   A
Sbjct: 594 TGPVMSMMPIFMVGVVFGLAMDYEVFLVTRMREAYVHGEKPNQAVVTGFKHGARVVTAAA 653

Query: 689 LTTAGGFLALLSAQLTAIHDFGRVLAVGIFASMFAAYL-VTPAILQLEFGRK 739
           +     F   + +  + +   G  LA+ +F   F   + + PA+L L  G+K
Sbjct: 654 VIMMAVFAGFIGSSESMVKMIGFGLAIAVFFDAFVVRMAIVPAVLAL-LGKK 704


>sp|P54881|MML4_MYCLE PUTATIVE MEMBRANE PROTEIN MMPL4 >gi|699243|gb|AAA63006.1| (U15183)
           transport protein [Mycobacterium leprae]
           Length = 959
           
 Score = 87.4 bits (213), Expect = 5e-16
 Identities = 77/337 (22%), Positives = 141/337 (40%), Gaps = 20/337 (5%)

Query: 137 PEARNGLISGDYSSTIIIVNLNREKNQKALVRVYNDIEREIERTNFPQGVEVVLTGDLGI 196
           P    G  S D  +  + ++L   + +       + + + + +T  P G+   +TG   +
Sbjct: 126 PLTAPGAQSNDGKAAYVQLSLAGNQGELLAQESIDAVRKIVVQTPAPPGITAWVTGASAL 185

Query: 197 TYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPLVPLIF------GVVMTLGF 250
              +       M R  A S I++++ LL  Y+S I +++ L  +        GVV  LG 
Sbjct: 186 IADMHHSGDKSMIRITATSVIVILVTLLLVYRSFITVILLLFTVGIESAVARGVVALLGH 245

Query: 251 MGLLGIPLDIATTTVGAMIIGMGIDYGVHVTNRYYEERGKGKSLEEAAEEAIAETGKALL 310
            GL+G+    A   + ++ I  G DYG+ +T RY E R   ++ E A       T   +L
Sbjct: 246 TGLIGLST-FAVNLLTSLAIAAGTDYGIFITGRYQEARQANENKEAAFYTMYRGTFHVIL 304

Query: 311 GAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVTPALAILEEEFREKVMKK 370
           G+ LT       LS + +P  + L V   +G+ +A   A+ + PA+  +   F   + + 
Sbjct: 305 GSGLTISGATFCLSFARMPYFQTLGVPCAVGMLIAVAVALTLGPAVLTVGSRF--GLFEP 362

Query: 371 KEIIAIGGGKSKISFIFSMLGKAIKRSPWTALLIALIISGVSLYGASKITTEVRLEKMIP 430
           K +I + G        +  +G  + R P   L+    I+ V L       T  +    +P
Sbjct: 363 KRLIKVRG--------WRRIGTVVVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLP 414

Query: 431 TDLPEIQALSDIRSEFGG---QDEVTILIKADDVRDP 464
             +P  Q  +     F     + E+ ++    D+R+P
Sbjct: 415 ASIPANQGFAAADRHFPQARMKPEILMIESDHDMRNP 451


>sp|O50439|MMLA_MYCTU PUTATIVE MEMBRANE PROTEIN MMPL10 >gi|7479028|pir||G70876 probable
           transmembrane protein - Mycobacterium tuberculosis
           (strain H37RV) >gi|2695967|emb|CAA15860.1| (AL010186)
           mmpL10 [Mycobacterium tuberculosis]
           Length = 1002
           
 Score = 86.2 bits (210), Expect = 1e-15
 Identities = 89/372 (23%), Positives = 159/372 (41%), Gaps = 23/372 (6%)

Query: 117 ILGRLPKNMDEVKFVLNMLP-PEARNGLISGDYSSTIIIVNLNREKNQKALVRVYNDIER 175
           ++ RL  +  +V  + + L  P  R  L S D  + I+ + L  +         Y D+ER
Sbjct: 78  LVDRLRNDAKDVVMLQDFLTTPPLREVLGSKDGKAWILPIGLAGDLGTPKSYHAYTDVER 137

Query: 176 EIERTNFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLV 235
            ++RT     +   +TG       + +    D         +++++IL+  Y++P+ ML+
Sbjct: 138 IVKRTVAGTTLTANVTGPAATVADLTDAGARDRASIELAIAVMLLVILMVIYRNPVTMLL 197

Query: 236 PLVPL------IFGVVMTLGFMGLLGIPLDIATTTVGAMIIGMGIDYGVHVTNRYYEERG 289
           PLV +         +V  +  +G L +  + A   + AMI G G DY V + +RY+E   
Sbjct: 198 PLVTIGASLMTAQALVAGVSLVGGLAVS-NQAIVLLSAMIAGAGTDYAVFLISRYHEYVR 256

Query: 290 KGKSLEEAAEEAIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNA 349
            G+  E A + A+   GK +  +A T    FL +  + L     +  +L +G+ ++ L A
Sbjct: 257 LGEHPERAVQRAMMSVGKVIAASAATVGITFLGMRFAKLGVFSTVGPALAIGIAVSFLAA 316

Query: 350 VIVTPALAILEEEFREKVMKKKEIIAIGGGKSKISFIFSMLGKAIKRSPWTALLIALIIS 409
           V + PA+ +L    R  V  + E         +++  +   G  I R P  A L A +I 
Sbjct: 317 VTLLPAILVLASP-RGWVAPRGE---------RMATFWRRAGTRIVRRP-KAYLGASLIG 365

Query: 410 GVSLYG-ASKITTEVRLEKMIPTDLPEIQALSDIRSEFGGQD---EVTILIKADDVRDPT 465
            V+L   AS         K +P   P     + +   F       E  I+  A D+R P 
Sbjct: 366 LVALASCASLAHFNYDDRKQLPPSDPSSVGYAAMEHHFSVNQTIPEYLIIHSAHDLRTPR 425

Query: 466 LVRDILRFEREI 477
            + D+ +  + +
Sbjct: 426 GLADLEQLAQRV 437


>sp|Q11171|MML2_MYCTU PUTATIVE MEMBRANE PROTEIN MMPL2 >gi|7478399|pir||F70746 probable
           mmpL2 protein - Mycobacterium tuberculosis (strain
           H37RV) >gi|1449306|emb|CAB00933.1| (Z77162) mmpL2
           [Mycobacterium tuberculosis]
           Length = 968
           
 Score = 85.0 bits (207), Expect = 3e-15
 Identities = 84/367 (22%), Positives = 150/367 (39%), Gaps = 28/367 (7%)

Query: 137 PEARNGLISGDYSSTIIIVNLNREKNQKALVRVYNDIEREIERTNFPQGVEVVLTGDLGI 196
           P    G  S D  +  ++V L      +A   V+  +   ++ T  P GV+  +TG   +
Sbjct: 124 PLTAAGSQSADDRAAYVVVYLVGNNETEAYDSVHA-VRHMVDTTPPPHGVKAYVTGPAAL 182

Query: 197 TYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPLVPLIFGVVMTLGFMGLLGI 256
                E     + +  AI+ +++  +LL  Y+S I  ++ L+ +   +    GF+ LL  
Sbjct: 183 NADQAEAGDKSIAKVTAITSMVIAAMLLVIYRSVITAVLVLIMVGIDLGAIRGFIALLAD 242

Query: 257 P-----LDIATTTVGAMIIGMGIDYGVHVTNRYYEERGKGKSLEEAAEEAIAETGKALLG 311
                    AT  +  M I    DY + +  RY+E R  G+  E A       T   +LG
Sbjct: 243 HNIFSLSTFATNLLVLMAIAASTDYAIFMLGRYHESRYAGEDRETAFYTMFHGTAHVILG 302

Query: 312 AALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVTPALAILEEEFREKVMKKK 371
           + LT       LS + LP  + L   + +G+ +A L A+ + PA+  +   F+    K++
Sbjct: 303 SGLTIAGAMYCLSFARLPYFETLGAPIAIGMLVAVLAALTLGPAVLTVGSFFKLFDPKRR 362

Query: 372 EIIAIGGGKSKISFIFSMLGKAIKRSPWTALLIALIISGVSLYGASKITTEVRLEKMIPT 431
                       +  +  +G AI R P   L    +++ + L       T   L K +P 
Sbjct: 363 ----------MNTRRWRRVGTAIVRWPGPVLAATCLVASIGLLALPSYRTTYDLRKFMPA 412

Query: 432 DLPEI--QALSDIRSEFGGQDEVTILIKAD-DVRDPTLVRDILRFEREIKADSYINNVFE 488
            +P     A +  R      +   +LI+ D D+R+P    D+L  ++  K      N++ 
Sbjct: 413 SMPSNVGDAAAGRRFSRARLNPEVLLIETDHDMRNPV---DMLVLDKVAK------NIYH 463

Query: 489 TQSIADV 495
           +  I  V
Sbjct: 464 SPGIEQV 470


>sp|O53735|MML4_MYCTU PUTATIVE MEMBRANE PROTEIN MMPL4 >gi|7478403|pir||C70831 probable
           mmpL4 protein - Mycobacterium tuberculosis (strain
           H37RV) >gi|2909525|emb|CAA17407.1| (AL021932) mmpL4
           [Mycobacterium tuberculosis]
           Length = 967
           
 Score = 84.7 bits (206), Expect = 3e-15
 Identities = 79/365 (21%), Positives = 147/365 (39%), Gaps = 23/365 (6%)

Query: 137 PEARNGLISGDYSSTIIIVNLNREKNQKALVRVYNDIEREIERTNFPQGVEVVLTGDLGI 196
           P    G+ S D  +  + ++L   +           +   +E T  P G++  +TG   +
Sbjct: 129 PLTAAGVQSNDGKAAYVQLSLAGNQGTPLANESVEAVRSIVESTPAPPGIKAYVTGPSAL 188

Query: 197 TYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPLVPL------IFGVVMTLGF 250
              +       M R   ++  ++ ++LL  Y+S I +++ L+ +        GVV  LG 
Sbjct: 189 AADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITVVLLLITVGVELTAARGVVAVLGH 248

Query: 251 MGLLGIPLDIATTTVGAMIIGMGIDYGVHVTNRYYEERGKGKSLEEAAEEAIAETGKALL 310
            G +G+    A + + ++ I  G DYG+ +  RY E R  G+  E A       T   +L
Sbjct: 249 SGAIGLTT-FAVSLLTSLAIAAGTDYGIFIIGRYQEARQAGEDKEAAYYTMYRGTAHVIL 307

Query: 311 GAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVTPALAILEEEFREKVMKK 370
           G+ LT       LS + +P  + L +   +G+ +A   AV +T   A+L    R  +   
Sbjct: 308 GSGLTIAGATFCLSFARMPYFQTLGIPCAVGMLVAV--AVALTLGPAVLHVGSRFGLFDP 365

Query: 371 KEIIAIGGGKSKISFIFSMLGKAIKRSPWTALLIALIISGVSLYGASKITTEVRLEKMIP 430
           K ++ + G        +  +G  + R P   L+    I+ V L       T       +P
Sbjct: 366 KRLLKVRG--------WRRVGTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLP 417

Query: 431 TDLPEIQALSDIRSEFGG---QDEVTILIKADDVRDPTLVRDILRFEREIKADSYINNVF 487
             +P  Q  +     F     + E+ ++    D+R+P    D L  ++  K    +  + 
Sbjct: 418 DFIPANQGYAAADRHFSQARMKPEILMIESDHDMRNPA---DFLVLDKLAKGIFRVPGIS 474

Query: 488 ETQSI 492
             Q+I
Sbjct: 475 RVQAI 479


>sp|O07800|MML8_MYCTU PUTATIVE MEMBRANE PROTEIN MMPL8 >gi|7478406|pir||C70522 probable
           mmpL8 protein - Mycobacterium tuberculosis (strain
           H37RV) >gi|3261809|emb|CAB10022.1| (Z97188) mmpL8
           [Mycobacterium tuberculosis]
           Length = 1089
           
 Score = 82.7 bits (201), Expect = 1e-14
 Identities = 87/366 (23%), Positives = 162/366 (43%), Gaps = 44/366 (12%)

Query: 137 PEARNGLISGDYSSTIIIV----NLNREKNQKALVRVYNDIEREIERTNFPQGVEVVLTG 192
           P  R  + S D  + I+ V    +L   ++++A  RV + +E ++  +         LTG
Sbjct: 144 PPLRELMTSKDNQAWILPVGLPGDLGSTQSKQAYARVADIVEHQVAGSTLTAN----LTG 199

Query: 193 DLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPLVPLIFGVVMTLGFMG 252
                  +    Q D +R      I++++ILL  Y +PI M++PL+ +   VV+    + 
Sbjct: 200 PAATVADLNLTGQRDRSRIEFAITILLLVILLIIYGNPITMVLPLITIGMSVVVAQRLVA 259

Query: 253 LLGIP-LDIATTTV---GAMIIGMGIDYGVHVTNRYYEERGKGKSLEEAAEEAIAETGKA 308
           + G+  L IA  ++     M++G G DY V + +RY++   +G   ++A ++A+   GK 
Sbjct: 260 IAGLAGLGIANQSIIFMSGMMVGAGTDYAVFLISRYHDYLRQGADSDQAVKKALTSIGKV 319

Query: 309 LLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVTPALAILEEEFREKVM 368
           +  +A T    FL +  + L  LK +   L + + +    AV + PAL +L    R  + 
Sbjct: 320 IAASAATVAITFLGMVFTQLGILKTVGPMLGISVAVVFFAAVTLLPALMVLTGR-RGWIA 378

Query: 369 KKKEIIAIGGGKSKISFIFSMLGKAIKRSPWTALLIALII-------SGVSLYGASKITT 421
            ++++             +   G  I R P T LL + ++       +G++ Y      T
Sbjct: 379 PRRDL---------TRRFWRSSGVHIVRRPKTHLLASALVLVILAGCAGLARYNYDDRKT 429

Query: 422 ----------EVRLEKMIPTDL--PE---IQALSDIRSEFGGQDEVTILIKADDVRDPTL 466
                        L+K  P++L  PE   IQ+ +D+R+     D   ++ +   V    +
Sbjct: 430 LPASVESSIGYAALDKHFPSNLIIPEYLFIQSSTDLRTPKALADLEQMVQRVSQVPGVAM 489

Query: 467 VRDILR 472
           VR I R
Sbjct: 490 VRGITR 495


>emb|CAB56653.1| (AL121596) putative membrane transport protein [Streptomyces
           coelicolor A3(2)]
           Length = 765
           
 Score = 82.3 bits (200), Expect = 2e-14
 Identities = 116/565 (20%), Positives = 222/565 (38%), Gaps = 80/565 (14%)

Query: 218 IVVLILLYFYKSPIRMLVPLVPLIFGVVMTLGFMGLLGIPLDIATTTVG-AMIIGM--GI 274
           +  ++LL  + S     +PL+  + GV +TL  +  LG  L ++T +   AM+IG+  G+
Sbjct: 184 VAAVVLLITFGSLAAAGLPLITAVVGVALTLASIVALGSALGMSTASGDLAMMIGIAVGV 243

Query: 275 DYGVHVTNRYYEERGKGKSLEEAAEEAIAETGKALLGAALTTIAGFLALSISILPSLKRL 334
           DY + V +RY EER +G    EAA  A+   G A++ A LT +     LS+  +PSL ++
Sbjct: 244 DYALLVVSRYREERAEGHDAREAAGLAVGTAGSAVVFAGLTVVIALAGLSVIGVPSLTKM 303

Query: 335 SVSLVMGLGLAALNAVIVTPAL------AILEEEFRE-----------KVMKKKEIIAIG 377
            ++    + +A L  + + PAL      A+L    R+           K         + 
Sbjct: 304 GLAAAGAVVIAVLITLTLVPALCGFWPDALLARRVRKGRSAPPARRFRKGRSTPPARRLR 363

Query: 378 GG-------KSKISFIFSM-LGKAIKRSPWTALLIALIISGVSLYGASKITTEVRLEKMI 429
           GG       +++ +  +S+   + ++R P   LL + ++ G     A  +   +  ++  
Sbjct: 364 GGPGRGAARRTREAGAWSVRWARFVQRRPVPVLLGSAVLLGALAVPALDLRLGMPGDEAK 423

Query: 430 PTDLPEIQALSDIRSEFGG--QDEVTILIKADDVRDPTLVRDILRFEREIKADSYINNVF 487
           PT   E +A   +   FG      +T+++ A    DP                       
Sbjct: 424 PTSTTERRAYDALADGFGPGFNGPLTVVVDARQADDPRSA-------------------- 463

Query: 488 ETQSIADVVIQKYGYIPQDKEKISEAIEGSSLVSSDYSMTIIKLKGNFMGVTQSEFNRIM 547
              +++D +    G +     + + A + + + +   +             T      ++
Sbjct: 464 -VAAVSDRLAATAGVVSVAPPRFNAAKDTAVIQAVPAT-----------APTSERTEELV 511

Query: 548 EYFERAIQRADFPPGVKVELAGESYLNYVLNDLVNEELGKISTIGTLIVVMVVFAIFRRP 607
                     +   G   E+ G + LN  +   + + L     +   +  +++  +FR  
Sbjct: 512 HTIRDERHATESATGATFEVTGTTALNIDVARKMTDALIPYLLVVVGLAFLLLLVVFRSV 571

Query: 608 TVSIAMIMPMFL------GALWTI---GY-MGLAGI----PFSQTL-AGVVSMIVGLGVD 652
            V +   +   L      GAL TI   G+  GL G+    P   T+   +V ++ GL +D
Sbjct: 572 LVPLKAALGFLLSVGASFGALVTIFQNGHGAGLLGVEETGPVMSTMPLMLVGIVFGLAMD 631

Query: 653 YGMHITHRFLEELNEGNK--TPIITALESVGPGIFVGALTTAGGFLALLSAQLTAIHDFG 710
           Y + +  R  E +  G +    ++T     G  +   A+     F   ++   T +   G
Sbjct: 632 YQVFLVSRMREAVVHGERPAEAVVTGFRHSGRVVTAAAVIMTSVFAGFMTGGETLLKMVG 691

Query: 711 RVLAVGIFASMFAAYLV-TPAILQL 734
             LAV +    F   +   PA+L L
Sbjct: 692 FGLAVAVLFDAFVVRMAFVPAVLVL 716


>gb|AAF97217.1|AF271635_1 (AF271635) putative transport membrane protein C [Mycobacterium
           smegmatis]
           Length = 994
           
 Score = 81.5 bits (198), Expect = 3e-14
 Identities = 80/325 (24%), Positives = 133/325 (40%), Gaps = 23/325 (7%)

Query: 177 IERTNFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVP 236
           + RT  P+GV V +TG   +   +       + +  A++ +I+  +LL  Y+S I +++ 
Sbjct: 174 VARTPAPEGVSVYVTGAAPLVSDMQHSGNRSILKITAVTVVIIFAMLLMVYRSVITVILL 233

Query: 237 LVPLIFGVVMTLGFMGLLGIP--LDIATTTVGAMI---IGMGIDYGVHVTNRYYEERGKG 291
           L+ + F V    G +  LG      ++T  V  ++   I  G DYG+    RY E R  G
Sbjct: 234 LIMVGFEVAAARGIVAFLGANEVFVLSTFAVNMLVFLAIAAGTDYGIFFFGRYQEARAAG 293

Query: 292 KSLEEAAEEAIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVI 351
           +  E A           ++ + LT       L+ + LP    + V   +G+  A   AV 
Sbjct: 294 EDRETAYYSMYRGVTPVVMASGLTIAGAIFCLTFTRLPYFHTMGVPCAIGMLAAVAVAVT 353

Query: 352 VTPALAILEEEFREKVMKKKEIIAIGGGKSKISFIFSMLGKAIKRSPWTALLIALIISGV 411
           + PA   L         K+K  +    G          +G AI R P   L+ +L ++ V
Sbjct: 354 LVPAGVALAGRIGWLEPKRKMRVRRWRG----------IGTAIVRWPAPILVASLAVALV 403

Query: 412 SLYGASKITTEVRLEKMIPTDLPEIQALSDIRSEFGGQDEVT---ILIKAD-DVRDPTLV 467
            L       T       IP D+P     +     F  Q  +T   +++++D D+R+PT  
Sbjct: 404 GLLALPGYETSYNDRDYIPADIPANAGFAAADRHF-SQARMTPDILMVESDHDMRNPT-- 460

Query: 468 RDILRFEREIKADSYINNVFETQSI 492
            D L   +  KA   +  V   Q I
Sbjct: 461 -DFLVLNKIAKAIFKVRGVSRVQGI 484


>pir||E71280 probable antibiotic transport protein - syphilis spirochete
           >gi|3323098|gb|AAC65756.1| (AE001250) antibiotic
           transport protein, putative [Treponema pallidum]
           Length = 888
           
 Score = 80.4 bits (195), Expect = 7e-14
 Identities = 102/489 (20%), Positives = 202/489 (40%), Gaps = 50/489 (10%)

Query: 16  LAVVTMFLLILSAYGITQLRFETDLSKQLPEDLEAVKSYFTLQNEFGGSGSALIYVKIKN 75
           L  V   L +  A  +  LR + +  + +P++     +   + + FG     LI +K + 
Sbjct: 31  LVAVLSALTLFFAVQLRTLRLDNNNFRFIPKENSVRIADQRIDSTFGSQVPVLIGIKREY 90

Query: 76  NDNVVDIRDPKIIEAMYSLEQRLREKEYVTDTFSIADLMVQILGRLPKNMDEVKFVLNML 135
              V    DP  +  + SL +R+     V    +++ L  + LG    N+   + V +  
Sbjct: 91  TSVV----DPVFLADVRSLIERISAVPLVRAESTLSLLSAEYLGLRAGNIISERVVPDEF 146

Query: 136 PPEARN----------------GLISGDYSSTIIIVNLNREKNQ----------KALVRV 169
              A                   L+S D  S  I+V L+    +          +A++R+
Sbjct: 147 SGSAEEVQGVYRKLRDWDFYECSLVSRDLRSMQIVVFLDTSNEESSSPEAMAACRAIIRI 206

Query: 170 YNDIEREIERTNFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKS 229
               +    +T F  GV V    ++G      E   +D+   + +  +I+++ L   ++ 
Sbjct: 207 LGAWKSRDAQT-FVTGVTVF--NEMGN-----EASTHDLTLLVPLVVLIIIVALFVSFRR 258

Query: 230 PIRMLVPLVPLIFGVVMTLGFMGLLGIPLDIATTTVGAMIIGMGIDYGVHVTNRYY---E 286
              + +PL+ ++   V  LG M L  IPL I +  +  ++I +G  YG+H+ + Y+    
Sbjct: 259 LAGIFLPLLTVVISTVWALGAMALCAIPLSILSAILPVILIAVGSAYGIHIVSAYFYGAS 318

Query: 287 ERGKGKSLEEAAE--EAIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGL 344
            R      E  A   EA+ +  + +  +ALTT  GF++   + +  +    V   +G+  
Sbjct: 319 SRICSTRQEHRARIVEAVDKIIQPVFLSALTTFVGFVSFCFTSVVPIFEFGVFASVGVAS 378

Query: 345 AALNAVIVTPALAILEEEFREKVMKKKEIIAIGGGKSKISFIFSMLGKAIKRSPWTALLI 404
           A   A+++ P+L I+      +V       A   G   +    +     I     T L +
Sbjct: 379 AFAVALMLIPSLLIIRGP-ESRVCAH----APDAGHEHMDTAITGTLMVIAHHYRTVLFV 433

Query: 405 ALIISGVSLYGASKITTEVRLEKMIPTDLPEIQALSDIRSEFGGQDEVTILIKADDVRDP 464
           A +    SL G S++  +  L +    ++  +Q+   ++  FGG   +T+L+ +   RD 
Sbjct: 434 AFLAVVFSLVGMSRLVIDNVLTEYFEPEVTVVQSDRFMQQHFGGSRSLTVLV-STPARDG 492

Query: 465 TLVR-DILR 472
           ++ R D+L+
Sbjct: 493 SVARPDVLK 501


 Score = 77.3 bits (187), Expect = 6e-13
 Identities = 87/377 (23%), Positives = 163/377 (43%), Gaps = 55/377 (14%)

Query: 398 PWTALLIALIISGVSLYGASKITTEVRLE----KMIPTDLPEIQALSDIRSEFGGQDEVT 453
           PW   ++  ++S ++L+ A ++ T +RL+    + IP +     A   I S FG Q  V 
Sbjct: 28  PW---VLVAVLSALTLFFAVQLRT-LRLDNNNFRFIPKENSVRIADQRIDSTFGSQVPVL 83

Query: 454 ILIKAD--DVRDPTLVRDILRFEREIKADSYINNVFETQSIADVVIQKY----------- 500
           I IK +   V DP  + D+      I A   +      +S   ++  +Y           
Sbjct: 84  IGIKREYTSVVDPVFLADVRSLIERISAVPLVR----AESTLSLLSAEYLGLRAGNIISE 139

Query: 501 GYIPQDKEKISEAIEG------------SSLVSSDY-SMTIIKLKGNFMGVTQSEFNRIM 547
             +P +    +E ++G             SLVS D  SM I+         T +E +   
Sbjct: 140 RVVPDEFSGSAEEVQGVYRKLRDWDFYECSLVSRDLRSMQIVVFLD-----TSNEESSSP 194

Query: 548 EYFE--RAIQR---ADFPPGVKVELAGESYLNYVLNDLVNEELGKISTIGTLIVVMVVFA 602
           E     RAI R   A      +  + G +  N + N+    +L  +  +  LI+++ +F 
Sbjct: 195 EAMAACRAIIRILGAWKSRDAQTFVTGVTVFNEMGNEASTHDLTLLVPLVVLIIIVALFV 254

Query: 603 IFRRPTVSIAMIMPMFLGALWTIGYMGLAGIPFSQTLAGVVSMIVGLGVDYGMHITHRF- 661
            FRR       ++ + +  +W +G M L  IP S   A +  +++ +G  YG+HI   + 
Sbjct: 255 SFRRLAGIFLPLLTVVISTVWALGAMALCAIPLSILSAILPVILIAVGSAYGIHIVSAYF 314

Query: 662 ------LEELNEGNKTPIITALESVGPGIFVGALTTAGGFLALLSAQLTAIHDFGRVLAV 715
                 +    + ++  I+ A++ +   +F+ ALTT  GF++     +  I +FG   +V
Sbjct: 315 YGASSRICSTRQEHRARIVEAVDKIIQPVFLSALTTFVGFVSFCFTSVVPIFEFGVFASV 374

Query: 716 GIFASMFAAYLVTPAIL 732
           G+ ++   A ++ P++L
Sbjct: 375 GVASAFAVALMLIPSLL 391


 Score = 76.9 bits (186), Expect = 8e-13
 Identities = 67/256 (26%), Positives = 112/256 (43%), Gaps = 15/256 (5%)

Query: 498 QKYGYIPQDKEKISEAIEGSSLVSSDYSMTIIK-------LKGNFMGVT--QSEFNRIME 548
           +KYG   +  E++ E I G  L+ S   + ++        LK N    T  Q +   ++E
Sbjct: 637 KKYGV--KTSEELQEIISGYLLLLSGKGLGLVDRAVDPRALKMNIQLGTKGQQDSYGVIE 694

Query: 549 YFERAIQRADFPPGVKVELAGESYLNYVLNDLVNEELGKISTIGTLIVVMVVFAI-FRRP 607
             ++ I R +FP  V  E  G   +   LNDLV +    IS + +L VV ++ A+ +R  
Sbjct: 695 AVKKFI-RENFPQDVHAEFGGSVLVEQSLNDLVVQSQ-LISLVFSLCVVFIIIAVHYRSL 752

Query: 608 TVSIAMIMPMFLGALWTIGYMGLAGIPFSQTLAGVVSMIVGLGVDYGMHITHRFLEELNE 667
              I   +P+ +  L   G MG  GI  +     V     G+GVDY +H    +     E
Sbjct: 753 FAGIIGTLPLGVSVLVNFGVMGFFGIKLNICTTMVAGFSSGIGVDYTIHYLAAYRRAWKE 812

Query: 668 -GNKTPIITALESVGPGIFVGALTTAGGFLALLSAQLTAIHDFGRVLAVGIFASMFAAYL 726
            G K  +       G  I    L+   GF  L+ ++   + DFG ++ + +  S  A+  
Sbjct: 813 CGGKDFLTQTFYGSGRAILFNVLSVGSGFAVLMLSKFNVLADFGLLMVLAMLTSSVASLT 872

Query: 727 VTPAILQLEFGRKISK 742
           + P +L +   R I++
Sbjct: 873 LLPTLLNVVKPRFITR 888


 Score = 71.0 bits (171), Expect = 4e-11
 Identities = 49/204 (24%), Positives = 94/204 (46%), Gaps = 3/204 (1%)

Query: 155 VNLNREKNQKALVRVYNDIE--REIERTNFPQGVEVVLTGDLGITYKILEMLQNDMNRTM 212
           + +N +   K     Y  IE  ++  R NFPQ V     G + +   + +++      ++
Sbjct: 675 LKMNIQLGTKGQQDSYGVIEAVKKFIRENFPQDVHAEFGGSVLVEQSLNDLVVQSQLISL 734

Query: 213 AISGIIVVLILLYFYKSPIRMLVPLVPLIFGVVMTLGFMGLLGIPLDIATTTVGAMIIGM 272
             S  +V +I+   Y+S    ++  +PL   V++  G MG  GI L+I TT V     G+
Sbjct: 735 VFSLCVVFIIIAVHYRSLFAGIIGTLPLGVSVLVNFGVMGFFGIKLNICTTMVAGFSSGI 794

Query: 273 GIDYGVHVTNRYYEERGKGKSLEEAAEEAIAETGKALLGAALTTIAGFLALSISILPSLK 332
           G+DY +H     Y    K    ++   +    +G+A+L   L+  +GF  L +S    L 
Sbjct: 795 GVDYTIHYL-AAYRRAWKECGGKDFLTQTFYGSGRAILFNVLSVGSGFAVLMLSKFNVLA 853

Query: 333 RLSVSLVMGLGLAALNAVIVTPAL 356
              + +V+ +  +++ ++ + P L
Sbjct: 854 DFGLLMVLAMLTSSVASLTLLPTL 877


>sp|Q50585|MMLC_MYCTU PUTATIVE MEMBRANE PROTEIN MMPL12 >gi|7478398|pir||B70723 probable
           mmpL12 protein - Mycobacterium tuberculosis (strain
           H37RV) >gi|1477435|emb|CAB01394.1| (Z77826) mmpL12
           [Mycobacterium tuberculosis]
           Length = 1146
           
 Score = 79.2 bits (192), Expect = 2e-13
 Identities = 77/352 (21%), Positives = 158/352 (44%), Gaps = 25/352 (7%)

Query: 137 PEARNGLISGDYSSTIIIVNLNREKNQKALVRVYNDIEREIERTNFPQGVEVVLTGDLGI 196
           PE +  L S D  +  + +    +         +  +   +++T     + V L+G +  
Sbjct: 126 PEMKELLASKDNKAWNLPITFAGDAASPETQAAFKRVAAIVKQTVAGTSLTVHLSGPIAT 185

Query: 197 TYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPLVPLIFGVVM---TLGFMGL 253
              + E+ + D+      + + V++IL+  Y++ + MLVPL  +   VV    TL  +  
Sbjct: 186 VADLTELGEKDVRIIEIGTAVSVLIILILVYRNLVTMLVPLATIGASVVTAQGTLSGLAE 245

Query: 254 LGIPLDI-ATTTVGAMIIGMGIDYGVHVTNRYYEERGKGKSLEEAAEEAIAETGKALLGA 312
            G+ +++ A   + A++IG G DY V + +RY++    G+  + A ++A+   GK +  +
Sbjct: 246 FGLAVNMQAIVFMSAVMIGAGTDYAVFLISRYHDYVRHGEKSDMAVKKALMSIGKVITAS 305

Query: 313 ALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVTPALAILEEEFREKVMKKKE 372
           A T    FLA+  + L     +  ++ + + ++ L AV + PA+  L    R  +  +++
Sbjct: 306 AATVAVTFLAMVFTKLEVFSAVGPAIAVAITVSLLGAVTLLPAILTLTGR-RGWIKPRRD 364

Query: 373 IIAIGGGKSKISFIFSMLGKAIKRSPWTALLIALIISGVSLYGASKITTEVRLE----KM 428
           + +    +S +        + ++RS  T  L+  +I  V+L G    T  +R      K 
Sbjct: 365 LTSRMWRRSGV--------RIVRRS--TIHLVGSLIVLVALAGC---TLLIRFNYDDLKT 411

Query: 429 IPTDLPEIQALSDIRSEF--GGQDEVTILIKAD-DVRDPTLVRDILRFEREI 477
           +P  +  ++    +   F       + + IK+  D+R P  + DI    REI
Sbjct: 412 VPQHVESVKGYEAMNRHFPMNAMTPMVLFIKSPRDLRTPGALADIEMMSREI 463


>sp|Q49619|MMLA_MYCLE PUTATIVE MEMBRANE PROTEIN MMPL10 >gi|2145979|pir||S72698 transport
           protein tp1 - Mycobacterium leprae
           >gi|466786|gb|AAA17062.1| (U00010) transport protein
           (similarity to antibiotic transport protein actII-3 from
           S.coelicolor); tp1; Lepb1170_C1_181 [Mycobacterium
           leprae]
           Length = 1008
           
 Score = 78.0 bits (189), Expect = 3e-13
 Identities = 83/377 (22%), Positives = 157/377 (41%), Gaps = 26/377 (6%)

Query: 117 ILGRLPKNMDEVKFVLNMLP-PEARNGLISGDYSSTIIIVNLNREKNQKALVRVYNDIER 175
           ++ RL  +  +V  + + L  P     L+S D  + I+ + L  E    A  + Y  +  
Sbjct: 104 LVDRLRNDTKDVVVLQDFLSTPPLHELLVSKDGKAWILPIVLAGELGTSASYQAYAGVAG 163

Query: 176 EIERT---NFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIR 232
            +++T        ++  LTG       + +    D      +  ++++ IL+  Y++PI 
Sbjct: 164 IVKQTLESTAGSSLKANLTGPASTVADLTDAGARDRTSIELVIAVLLLTILMIIYRNPIT 223

Query: 233 MLVPLVPLIFGVVMTLGFMGLLGIPLDIATTT-----VGAMIIGMGIDYGVHVTNRY--Y 285
           ML+PL+ +   ++     +  + +   +A +      + AMI G G DY V + +RY  Y
Sbjct: 224 MLLPLITIGASLMTAQAVVSGVSVLAGLAVSNQMIVLLSAMIAGAGTDYAVFLISRYHDY 283

Query: 286 EERGKGKSLEE--AAEEAIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLG 343
              G G + +   A  +A+   GK +  +A T    FL +S + +     +  +L +G+ 
Sbjct: 284 IRMGSGSAQDAGCAVRQALISLGKVIAASAATVGITFLGMSFTKIRVFSTVGPALAIGIA 343

Query: 344 LAALNAVIVTPALAILEEEFREKVMKKKEIIAIGGGKSKISFIFSMLGKAIKRSPWTALL 403
           +A L AV + PAL +L    R  V  +++         +    +   G  I R P   L 
Sbjct: 344 VAFLAAVTLMPALLVLAGT-RGWVAPRRD---------RAGAFWRRTGVRIVRRPVAYLS 393

Query: 404 IALIISGVSLYGASKITTEVRLEKMIPTDLPEIQALSDIRSEFG-GQ--DEVTILIKADD 460
            +++I  V    AS +       K IP         + + S F  GQ   E  ++    D
Sbjct: 394 ASMVILIVLALCASLVRFNYDDRKQIPASDESSVGYAALESHFPVGQAIPEYLLIQSPHD 453

Query: 461 VRDPTLVRDILRFEREI 477
           +R P  + D+    + +
Sbjct: 454 LRTPRALADMAELAQRV 470


>pir||A75560 conserved hypothetical protein - Deinococcus radiodurans  (strain
           R1) >gi|6457770|gb|AAF09696.1|AE001873_6 (AE001873)
           conserved hypothetical protein [Deinococcus radiodurans]
           Length = 749
           
 Score = 76.5 bits (185), Expect = 1e-12
 Identities = 125/650 (19%), Positives = 258/650 (39%), Gaps = 58/650 (8%)

Query: 120 RLPKNMDEVKFVLNMLPPEARNGLISGDYSSTIIIVNLN---REKNQKALVRVYNDIERE 176
           R    + +VK V  +LP + R GL S D + T+ +       +E  ++A+ R+     R 
Sbjct: 100 RFVSGLRDVKGVTRVLPAQ-RGGLGSRDAAGTLALTVAQIPLQEDGKEAVARI-----RA 153

Query: 177 IERTNFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVP 236
             R      +++ +TG   I     E+ + D  R+  ++  ++ L+LL  + + +   +P
Sbjct: 154 YVRRVASPALDIRVTGGQAIADDFTELAEADTKRSEFVALPLIALLLLLVFGALVATGLP 213

Query: 237 LVPLIFGVVMTLGFMGLLGIPLDIAT---TTVGAMIIGMGIDYGVHVTNRYYEERGKGKS 293
           LV  +  + + +  +  L   ++++T   + V  + +G GIDY + + NR+ EE  +  +
Sbjct: 214 LVIGMLSISVAMAGLYFLTTVMEVSTFAQSVVTMLGLGAGIDYALLMVNRFREELARRGN 273

Query: 294 LEEAAEEAIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVT 353
             EAA   +   G+++L +  T       L +  L  ++ + +  V+ + L  L ++   
Sbjct: 274 AAEAAARTVETAGRSVLFSGSTVAIAMAGLLLPPLSFVRSIGIGGVLAVVLTVLASLTAL 333

Query: 354 PALAILEEEFREKVMKKKEIIAIGGGKSKISFIFSMLGKAIKRSPWTALLIALIISGVSL 413
           PAL  L     ++V   + + +     +  S  ++   + +   P   ++++     +  
Sbjct: 334 PALLTL---LGDRVNAPRLLRSTWAQSAGASAAWTAFARRVTARPLAVVVLSTAFLLLLA 390

Query: 414 YGASKITTEVRLEKMIPTDLPEIQALSDIRSEFGG--QDEVTILIKADDVRDPTLVRDIL 471
             AS++ T       +   +    AL D+R    G    +  +L+  +  R         
Sbjct: 391 VPASRMKTGYAGAWGLVPGVESRDALQDVRDMGAGGLLSQYEVLLDLEGKRYTP------ 444

Query: 472 RFEREIKADSYINNVFETQSIADVVIQKYGYIPQDKEKISEAIEGSSLVSSDYSMTIIKL 531
             ++  +  + +N++     +  V+       P D +             S  +      
Sbjct: 445 --DQSARFQAVVNDLRALPGVRAVL--SPFLTPADLQAAGGGTSDGLAALSLLTQRSFSR 500

Query: 532 KGNFMGVTQSEFNR----IMEYFERAIQRADFPPGVKVELAGESYLNYVLNDLVNEELGK 587
              F+ VT    +     +   FE+ ++      G +  + G        ++ + + L  
Sbjct: 501 DRTFLRVTVVPDDTLRADLAPAFEKRVRAVLEGSGSRFLVGGAPVGGREFSEAITDTLPT 560

Query: 588 ISTI---GTLIVVMVVFAIFRRPTVSIAMIMPMFLGA-----LWTI---GYMGLAGIPFS 636
           +      GT +++++ F     P  SI M   + +GA      W +    + GL G+P S
Sbjct: 561 VMLAVFGGTFVLLLLAFRSLLIPLKSIVM-NALTVGAAAGVVTWAVQEGHFAGLLGLPAS 619

Query: 637 QTLAGVV---------SMIVGLGVDYGMHITHRFLEELNEG--NKTPIITALESVGPGIF 685
              AGV+         +++ GL +DY + +  R  EE   G  N   ++ A+      I 
Sbjct: 620 ---AGVLDSSLPLLLFAVMFGLSMDYEIFLLSRVQEEHLAGASNDEAVVRAVGHTARIIT 676

Query: 686 VGALTTAGGFLALLSAQLTAIHDFGRVLAVGIFASMFAAYLV-TPAILQL 734
             A+     F A +  ++ A    G  LAV +        LV  PA L+L
Sbjct: 677 SAAVIMFIVFTAFMFGRVVATKSVGLGLAVAVVLDATLVRLVLVPAFLKL 726


>sp|Q53902|MMLA_STRCO PUTATIVE MEMBRANE PROTEIN ACTII-3 >gi|80715|pir||C40046 antibiotic
           transport-associated protein actII-3 - Streptomyces
           coelicolor >gi|153146|gb|AAA26691.1| (M64683) ORF3
           [Streptomyces coelicolor]
           Length = 711
           
 Score = 75.3 bits (182), Expect = 2e-12
 Identities = 55/214 (25%), Positives = 105/214 (48%), Gaps = 7/214 (3%)

Query: 151 TIIIVNLNREKNQKALVRVYNDIEREIERTNFPQGVEVVLTGDLGITYKILEMLQNDMNR 210
           T++ V+L ++   + L     D+ R I R + P G+ V +TG  G      E   +   +
Sbjct: 121 TVVNVHLGKD-GWEGLNAAAKDM-RAIARPSAPDGLGVHVTGPTGYAADSAESFSSADFK 178

Query: 211 TMAISGIIVVLILLYFYKSPIRMLVPLVPLIFGVVMTLGFMGLL----GIPLDIATTTV- 265
              ++ +IVV IL+  Y+SP+  L+P++     +V++   + LL    G+ ++  T  + 
Sbjct: 179 LTLVTLLIVVTILVVTYRSPLLWLLPMISAGMSLVISQAIVYLLAKNAGLTVNAQTAMIL 238

Query: 266 GAMIIGMGIDYGVHVTNRYYEERGKGKSLEEAAEEAIAETGKALLGAALTTIAGFLALSI 325
             +++G   DY + +  RY EE  + +   EA   A+   G A++ +A T     L L +
Sbjct: 239 TVLVLGAATDYALLLVARYREELRRHEDRHEAMAVALRRAGPAIVASAATVAVSMLVLLL 298

Query: 326 SILPSLKRLSVSLVMGLGLAALNAVIVTPALAIL 359
           + L S K L     +G+ +  L+ + + PAL ++
Sbjct: 299 AALNSTKGLGPVCAVGVLVGLLSMMTLLPALLVI 332


>pir||T23399 hypothetical protein K07C10.1 - Caenorhabditis elegans
           >gi|3878347|emb|CAA87375.1| (Z47074) similarity to
           transmembranous domains of the drosophila protein
           patched (Swiss Prot accession number P18502)
           [Caenorhabditis elegans]
           Length = 690
           
 Score = 74.5 bits (180), Expect = 4e-12
 Identities = 114/526 (21%), Positives = 206/526 (38%), Gaps = 60/526 (11%)

Query: 251 MGLLGIPLDIATTTVGAMIIGMGIDYGVHVTNRYYEERGKGKSLEEAAEEAIAETGKALL 310
           +G +G P +        +I+G+G+D    + N +  E GK KS ++A  +      +   
Sbjct: 151 LGWVGHPFNSIMCITPFLILGIGVDDAFLLLNCWRREEGKDKSAKQAENQLARVIREISP 210

Query: 311 GAALTTIAGFLALSISILPSLKRLSVSLVMGLGLA-----ALNAVIVTPA---------- 355
             A+T++   +A  +  L    ++S S  +G  LA      L  +I  P           
Sbjct: 211 SMAITSLTNTMAFGVGFLAPTPQMS-SFCLGTALAIVLDFLLEFLIFVPCMVLFYKKKPE 269

Query: 356 -LAILEEEF-REKVMKKKEIIAIGGGKSKISFIFSMLGKAIKRSPWTALLIALIIS--GV 411
            +AI  EEF  EK  K+ E     G  S+I+  +      +   P   L+I L  S    
Sbjct: 270 IIAIENEEFANEKTEKRSETST--GKYSRIN--WKCFTNLLLSVPGRVLVIILYFSIFTA 325

Query: 412 SLYGASKITTEVRLEKMIPTDLPEIQALSDIRSEFGGQDEVTILIKADDVRDPTLVRDI- 470
           S +G +K+       K  P+D   + +L+   S       +  L    D+++ T V +  
Sbjct: 326 SYFGVAKMEKTFDPSKTFPSDSKLVDSLASFTSIQVEYSPLNFLSSVPDLKNDTDVANFN 385

Query: 471 -----LRFEREIKADSYINNVF----ETQSIADVVIQKYGYIPQDKEKISEAIEGSSLVS 521
                L F  E   D   +N++    +  + +++  + Y ++ +  +    A  G+    
Sbjct: 386 EMLHKLEFREECYGDVGSHNMYRDYVQFLNYSNITDKSYNHLEKFLKGRGMADVGTIKYH 445

Query: 522 SDYSMTIIKLKGNFMGVTQSEFNRIMEYFERAIQRADFPPGVKVELAGESYLNYVLNDLV 581
            + + TII +  NF+ V Q          E+  +RA      +  L   S  N  L D  
Sbjct: 446 KEGNDTIIDMI-NFVVVCQGR--------EKWAERAVNVEKTRQILVDYSDYNITLFDYD 496

Query: 582 NEELGKISTI-GTLIVVMVVFAIFRRPTVSIAMIMPMFLG-----------ALWTIGYMG 629
                 I T+ G L+  + +   F   T++  +IMP F+            +   IG++ 
Sbjct: 497 GTIYDLIITVKGELVKSLAI--TFTCMTIACFVIMPSFVAPTIASVATVSISFCLIGFLS 554

Query: 630 LAGIPFSQTLAGVVSMIVGLGVDYGMHITHRF--LEELNEGNKTPIITA-LESVGPGIFV 686
           + G          V M +G  VDY  H+ + +    E + G+K  +IT+ L++VG  +  
Sbjct: 555 IWGQNLDPVTMIDVIMAIGFSVDYSAHVCYHYYCAREQHLGSKHEVITSVLQAVGRPVVE 614

Query: 687 GALTTAGGFLALLSAQLTAIHDFGRVLAVGIFASMFAAYLVTPAIL 732
            +LTT      L    +  I  F + + +     +       P +L
Sbjct: 615 ASLTTLLCMAPLFVVPVYMIQSFAKTVTLVTSFGLLHGLFFLPVVL 660


>sp|P96706|YDGH_BACSU PUTATIVE MEMBRANE PROTEIN YDGH >gi|7475936|pir||B69783 transporter
           homolog ydgH - Bacillus subtilis
           >gi|1881371|dbj|BAA19398.1| (AB001488) PROBABLE
           TRANSPORT PROTEIN, SIMILAR PRODUCT IN MYCOBACTERIUM
           LEPRAE. [Bacillus subtilis] >gi|2632865|emb|CAB12372.1|
           (Z99106) similar to transporter [Bacillus subtilis]
           >gi|2632878|emb|CAB12384.1| (Z99107) similar to
           transporter [Bacillus subtilis]
           Length = 885
           
 Score = 73.7 bits (178), Expect = 7e-12
 Identities = 84/405 (20%), Positives = 176/405 (42%), Gaps = 31/405 (7%)

Query: 123 KNMDEVKFVLNMLPPE--ARNGLISGDYSSTIIIVNL--NREKNQKALVRVYNDIEREIE 178
           K +D V+ V + L  E   ++ L+S D  + ++ V +  + +K +K    +Y  +     
Sbjct: 90  KKIDGVEEVTSPLSAEKEVKDQLMSKDKKTVLMPVTITGSDKKAEKIADEIYQIV----- 144

Query: 179 RTNFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPLV 238
               P  +   +TG   I        +  + +T  I+  +++ +LL  ++S +   +P+V
Sbjct: 145 ----PDDLTAYITGASLINQDFAHSSEEGLKKTEVITVCLIIGLLLIVFRSVVTPFIPIV 200

Query: 239 PLIFGVVMTLGFMGLLGIPLDIATTT-----VGAMIIGMGIDYGVHVTNRYYEERGKGKS 293
            + F  +++   +G+L   +D   +T     + A++ G+G DY + +  R+ EE   G  
Sbjct: 201 VVGFSYLISQSILGILVYNVDFPISTFTQTFLVAILFGIGTDYCILLLTRFREELANGHD 260

Query: 294 LEEAAEEAIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVT 353
            +EAA  A    GK L  +    + GF AL  +   ++ + +V + +G+G+  +    + 
Sbjct: 261 KKEAALIAYRTGGKTLFISGFAVLIGFSALGFAKF-AIFQSAVGVAVGVGILMIILYTLL 319

Query: 354 PALAILEEEFREKVMKKKEIIAIGGGKSKISFIFSMLGKAIKRSPWTALLIALIIS-GVS 412
           P   +   E  +     K++++    K     +++ LG+     P+  ++I ++I+    
Sbjct: 320 PLFMVTLGE--KLFWPSKKVLSHSDNK-----LWAFLGRHSVARPFLFIVITVVITLPFI 372

Query: 413 LYGASKITTEVRLEKMIPTDLPEIQALSDIRSEFGGQDEVTILIKADDVRDPTLVRDILR 472
           L    +I+ +   E  I +D   I+AL  I+  FG      I +     +D T    I  
Sbjct: 373 LTYDDQISFDSTAE--ISSDYKSIKALEAIKDGFGEGKAFPINVVVKGDKDLTTADTIPY 430

Query: 473 FEREIKADSYINNVFETQSIADVVIQKYG--YIPQDKEKISEAIE 515
                KA   +++V    +I     +K    YI      +S+ ++
Sbjct: 431 LGNISKAIEKVDHVDSVMTITQPTGKKIKDLYIDNQLGSVSDGLD 475


>emb|CAB86119.1| (AL163003) putative integral membrane protein [Streptomyces
           coelicolor A3(2)]
           Length = 743
           
 Score = 73.4 bits (177), Expect = 9e-12
 Identities = 61/248 (24%), Positives = 112/248 (44%), Gaps = 8/248 (3%)

Query: 218 IVVLILLYFYKSPIRMLVPLVPLIFGVVMTLGFMGLLGIPLDI---ATTTVGAMIIGMGI 274
           + +L+LL+ + S +  L+PL   +  +V T   + LLG    I   AT    A+ +G+GI
Sbjct: 186 LTLLLLLFVFGSVVSALLPLAIGLIAIVGTFAELFLLGSVASISITATNLTTALGLGLGI 245

Query: 275 DYGVHVTNRYYEERGKGKSLEEAAEEAIAETGKALLGAALTTIAGFLALSISILPSLKRL 334
           DY + + +R+ E+  KG S+++A    +   G+ +  +A T      AL +     L+  
Sbjct: 246 DYALLMVSRFREQLAKGASVDDAVRHTVHTAGRTVAFSAATVAVALAALLVFPQYFLRSF 305

Query: 335 SVSLVMGLGLAALNAVIVTPALAILEEEFREKVMKKKEIIAIGGGKSKISFIFSMLGKAI 394
             + V  + +AA++ + V PAL  +      K              S++ F   +   A+
Sbjct: 306 GYAGVGVVAIAAVSTLFVMPALLNVLGHRVNKGRLPWAGRTERHDDSRVPFWGRLARTAM 365

Query: 395 KRSPWTAL--LIALIISGVSLYGASKITTEVRLEKMIPTDLPEIQALSDIRSEFGGQDEV 452
           +R   TAL  L  L+++   L G   I+  +  E+ +P D    Q  + +   F G D  
Sbjct: 366 RRPALTALPVLAVLLLAASPLLG---ISIGIADERSLPEDAASRQVSARLAENFNGSDAA 422

Query: 453 TILIKADD 460
            + +  D+
Sbjct: 423 AVHVVMDE 430


>sp|P95211|MML1_MYCTU PUTATIVE MEMBRANE PROTEIN MMPL1 >gi|7478394|pir||A70634 probable
           mmpL1 protein - Mycobacterium tuberculosis (strain
           H37RV) >gi|1817718|emb|CAB06593.1| (Z84725) mmpL1
           [Mycobacterium tuberculosis]
           Length = 958
           
 Score = 71.8 bits (173), Expect = 3e-11
 Identities = 79/391 (20%), Positives = 151/391 (38%), Gaps = 34/391 (8%)

Query: 117 ILGRLPKNMDEVKFVLNML-PPEARNGLISGDYSSTIIIVNLNREKNQKALVRVYNDIER 175
           ++ +L ++   V+ + N    P    G  S D  +  + +NL  ++           ++R
Sbjct: 101 LVTKLSQDTTHVQHIENFWGDPLTAAGSQSADGKAAYVQLNLTGDQGGSQANESVAAVQR 160

Query: 176 EIERTNFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLV 235
            ++    P G++  +TG   +    +      ++    IS  ++ ++L   Y+S    L+
Sbjct: 161 IVDSVPPPPGIKAYVTGPGPLGADRVVYGDRSLHTITGISIAVIAIMLFIAYRSLSAALI 220

Query: 236 PLVPL------IFGVVMTLGFMGLLGIPLDIATTTVGAMIIGMGIDYGVHVTNRYYEERG 289
            L+ +      + G++ T     L+G+        V A+ I    DY + +  RY E R 
Sbjct: 221 MLLTVGLELLAVRGIISTFAVNDLMGLSTFTVNVLV-ALTIAASTDYIIFLVGRYQEARA 279

Query: 290 KGKSLEEAAEEAIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNA 349
            G++ E A       T   +L + LT       L  + LP    L+    +GL    L +
Sbjct: 280 TGQNREAAYYTMFGGTAHVVLASGLTVAGAMYCLGFTRLPYFNTLASPCAIGLVTVMLAS 339

Query: 350 VIVTPALAILEEEF-----REKVMKKKEIIAIGGGKSKISFIFSMLGKAIKRSPWTALLI 404
           + + PA+  +   F     +    K++               +  +G  + R P   L  
Sbjct: 340 LTLAPAIIAVASRFGLFDPKRATTKRR---------------WRRIGTVVVRWPGPVLAA 384

Query: 405 ALIISGVSLYGASKITTEVRLEKMIPTDLPEI--QALSDIRSEFGGQDEVTILIKAD-DV 461
            L+I+ + L    K  T       IP+  P       SD        +   ++++AD D+
Sbjct: 385 TLLIALIGLLALPKYQTNYNERYYIPSAAPSNIGYLASDRHFPQARMEPEVLMVEADHDL 444

Query: 462 RDPTLVRDILRFEREIKADSYINNVFETQSI 492
           R+PT   D+L  +R  K   +   +   QSI
Sbjct: 445 RNPT---DMLILDRIAKTVFHTPGIARVQSI 472


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.322    0.140    0.384 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 248335531
Number of Sequences: 2977
Number of extensions: 10391870
Number of successful extensions: 31594
Number of sequences better than 1.0e-10: 34
Number of HSP's better than  0.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 31386
Number of HSP's gapped (non-prelim): 111
length of query: 746
length of database: 189,106,746
effective HSP length: 60
effective length of query: 686
effective length of database: 153,197,526
effective search space: 105093502836
effective search space used: 105093502836
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.9 bits)
S2: 168 (69.9 bits)