BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB1101 (PAB1101) DE:Transport protein (746 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||A75018 transport protein PAB1101 - Pyrococcus abyssi (strai... 1435 0.0 pir||H71453 hypothetical protein PH0287 - Pyrococcus horikoshii ... 1267 0.0 sp|Q58957|YF62_METJA PUTATIVE MEMBRANE PROTEIN MJ1562 >gi|212893... 255 2e-66 gi|11498828 conserved hypothetical protein [Archaeoglobus fulgid... 231 3e-59 gi|11498071 conserved hypothetical protein [Archaeoglobus fulgid... 203 5e-51 gb|AAG19780.1| (AE005063) Vng1476c [Halobacterium sp. NRC-1] 173 5e-42 pir||D70131 conserved hypothetical integral membrane protein BB0... 145 1e-33 pir||E72272 conserved hypothetical protein - Thermotoga maritima... 141 3e-32 sp|O54101|MMLB_STRCO PUTATIVE MEMBRANE PROTEIN SC10A5.10C >gi|74... 115 2e-24 pir||D72329 hypothetical protein - Thermotoga maritima (strain M... 102 1e-20 gb|AAD44231.1|AF143772_37 (AF143772) TmtpB [Mycobacterium avium] 101 3e-20 sp|O53784|MML5_MYCTU PUTATIVE MEMBRANE PROTEIN MMPL5 >gi|7478343... 101 4e-20 emb|CAB90894.1| (AL355753) putative integral membrane protein. [... 97 6e-19 pir||B81282 probable integral membrane protein Cj1373 [imported]... 94 4e-18 emb|CAB89762.1| (AL354616) putative integral membrane protein. [... 94 5e-18 emb|CAB89749.1| (AL354616) putative membrane protein [Streptomyc... 92 2e-17 dbj|BAB04439.1| (AP001509) unknown conserved protein in others [... 89 1e-16 emb|CAB59662.1| (AL132674) putative membrane transport protein [... 87 5e-16 sp|P54881|MML4_MYCLE PUTATIVE MEMBRANE PROTEIN MMPL4 >gi|699243|... 87 5e-16 sp|O50439|MMLA_MYCTU PUTATIVE MEMBRANE PROTEIN MMPL10 >gi|747902... 86 1e-15 sp|Q11171|MML2_MYCTU PUTATIVE MEMBRANE PROTEIN MMPL2 >gi|7478399... 85 3e-15 sp|O53735|MML4_MYCTU PUTATIVE MEMBRANE PROTEIN MMPL4 >gi|7478403... 85 3e-15 sp|O07800|MML8_MYCTU PUTATIVE MEMBRANE PROTEIN MMPL8 >gi|7478406... 83 1e-14 emb|CAB56653.1| (AL121596) putative membrane transport protein [... 82 2e-14 gb|AAF97217.1|AF271635_1 (AF271635) putative transport membrane ... 82 3e-14 pir||E71280 probable antibiotic transport protein - syphilis spi... 80 7e-14 sp|Q50585|MMLC_MYCTU PUTATIVE MEMBRANE PROTEIN MMPL12 >gi|747839... 79 2e-13 sp|Q49619|MMLA_MYCLE PUTATIVE MEMBRANE PROTEIN MMPL10 >gi|214597... 78 3e-13 pir||A75560 conserved hypothetical protein - Deinococcus radiodu... 76 1e-12 sp|Q53902|MMLA_STRCO PUTATIVE MEMBRANE PROTEIN ACTII-3 >gi|80715... 75 2e-12 pir||T23399 hypothetical protein K07C10.1 - Caenorhabditis elega... 75 4e-12 sp|P96706|YDGH_BACSU PUTATIVE MEMBRANE PROTEIN YDGH >gi|7475936|... 74 7e-12 emb|CAB86119.1| (AL163003) putative integral membrane protein [S... 73 9e-12 sp|P95211|MML1_MYCTU PUTATIVE MEMBRANE PROTEIN MMPL1 >gi|7478394... 72 3e-11 >pir||A75018 transport protein PAB1101 - Pyrococcus abyssi (strain Orsay) >gi|5459097|emb|CAB50583.1| (AJ248288) Transport protein [Pyrococcus abyssi] Length = 746 Score = 1435 bits (3673), Expect = 0.0 Identities = 746/746 (100%), Positives = 746/746 (100%) Query: 1 MLRKIARVIVIYRHSLAVVTMFLLILSAYGITQLRFETDLSKQLPEDLEAVKSYFTLQNE 60 MLRKIARVIVIYRHSLAVVTMFLLILSAYGITQLRFETDLSKQLPEDLEAVKSYFTLQNE Sbjct: 1 MLRKIARVIVIYRHSLAVVTMFLLILSAYGITQLRFETDLSKQLPEDLEAVKSYFTLQNE 60 Query: 61 FGGSGSALIYVKIKNNDNVVDIRDPKIIEAMYSLEQRLREKEYVTDTFSIADLMVQILGR 120 FGGSGSALIYVKIKNNDNVVDIRDPKIIEAMYSLEQRLREKEYVTDTFSIADLMVQILGR Sbjct: 61 FGGSGSALIYVKIKNNDNVVDIRDPKIIEAMYSLEQRLREKEYVTDTFSIADLMVQILGR 120 Query: 121 LPKNMDEVKFVLNMLPPEARNGLISGDYSSTIIIVNLNREKNQKALVRVYNDIEREIERT 180 LPKNMDEVKFVLNMLPPEARNGLISGDYSSTIIIVNLNREKNQKALVRVYNDIEREIERT Sbjct: 121 LPKNMDEVKFVLNMLPPEARNGLISGDYSSTIIIVNLNREKNQKALVRVYNDIEREIERT 180 Query: 181 NFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPLVPL 240 NFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPLVPL Sbjct: 181 NFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPLVPL 240 Query: 241 IFGVVMTLGFMGLLGIPLDIATTTVGAMIIGMGIDYGVHVTNRYYEERGKGKSLEEAAEE 300 IFGVVMTLGFMGLLGIPLDIATTTVGAMIIGMGIDYGVHVTNRYYEERGKGKSLEEAAEE Sbjct: 241 IFGVVMTLGFMGLLGIPLDIATTTVGAMIIGMGIDYGVHVTNRYYEERGKGKSLEEAAEE 300 Query: 301 AIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVTPALAILE 360 AIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVTPALAILE Sbjct: 301 AIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVTPALAILE 360 Query: 361 EEFREKVMKKKEIIAIGGGKSKISFIFSMLGKAIKRSPWTALLIALIISGVSLYGASKIT 420 EEFREKVMKKKEIIAIGGGKSKISFIFSMLGKAIKRSPWTALLIALIISGVSLYGASKIT Sbjct: 361 EEFREKVMKKKEIIAIGGGKSKISFIFSMLGKAIKRSPWTALLIALIISGVSLYGASKIT 420 Query: 421 TEVRLEKMIPTDLPEIQALSDIRSEFGGQDEVTILIKADDVRDPTLVRDILRFEREIKAD 480 TEVRLEKMIPTDLPEIQALSDIRSEFGGQDEVTILIKADDVRDPTLVRDILRFEREIKAD Sbjct: 421 TEVRLEKMIPTDLPEIQALSDIRSEFGGQDEVTILIKADDVRDPTLVRDILRFEREIKAD 480 Query: 481 SYINNVFETQSIADVVIQKYGYIPQDKEKISEAIEGSSLVSSDYSMTIIKLKGNFMGVTQ 540 SYINNVFETQSIADVVIQKYGYIPQDKEKISEAIEGSSLVSSDYSMTIIKLKGNFMGVTQ Sbjct: 481 SYINNVFETQSIADVVIQKYGYIPQDKEKISEAIEGSSLVSSDYSMTIIKLKGNFMGVTQ 540 Query: 541 SEFNRIMEYFERAIQRADFPPGVKVELAGESYLNYVLNDLVNEELGKISTIGTLIVVMVV 600 SEFNRIMEYFERAIQRADFPPGVKVELAGESYLNYVLNDLVNEELGKISTIGTLIVVMVV Sbjct: 541 SEFNRIMEYFERAIQRADFPPGVKVELAGESYLNYVLNDLVNEELGKISTIGTLIVVMVV 600 Query: 601 FAIFRRPTVSIAMIMPMFLGALWTIGYMGLAGIPFSQTLAGVVSMIVGLGVDYGMHITHR 660 FAIFRRPTVSIAMIMPMFLGALWTIGYMGLAGIPFSQTLAGVVSMIVGLGVDYGMHITHR Sbjct: 601 FAIFRRPTVSIAMIMPMFLGALWTIGYMGLAGIPFSQTLAGVVSMIVGLGVDYGMHITHR 660 Query: 661 FLEELNEGNKTPIITALESVGPGIFVGALTTAGGFLALLSAQLTAIHDFGRVLAVGIFAS 720 FLEELNEGNKTPIITALESVGPGIFVGALTTAGGFLALLSAQLTAIHDFGRVLAVGIFAS Sbjct: 661 FLEELNEGNKTPIITALESVGPGIFVGALTTAGGFLALLSAQLTAIHDFGRVLAVGIFAS 720 Query: 721 MFAAYLVTPAILQLEFGRKISKEVRE 746 MFAAYLVTPAILQLEFGRKISKEVRE Sbjct: 721 MFAAYLVTPAILQLEFGRKISKEVRE 746 >pir||H71453 hypothetical protein PH0287 - Pyrococcus horikoshii >gi|3256676|dbj|BAA29359.1| (AP000001) 787aa long hypothetical protein [Pyrococcus horikoshii] Length = 787 Score = 1267 bits (3242), Expect = 0.0 Identities = 635/747 (85%), Positives = 712/747 (95%), Gaps = 2/747 (0%) Query: 1 MLRKIARVIVIYRHSLAVVTMFLLILSAYGITQLRFETDLSKQLPEDLEAVKSYFTLQNE 60 MLRKIAR+IV+YRHSLAV+T+FLLILS YGIT+L+FE+DLSKQLPEDLEAVK+YFTLQNE Sbjct: 42 MLRKIARIIVVYRHSLAVITIFLLILSGYGITKLKFESDLSKQLPEDLEAVKNYFTLQNE 101 Query: 61 FGGSGSALIYVKIKNNDNVVDIRDPKIIEAMYSLEQRLREKEYVTDTFSIADLMVQILGR 120 FGGSGSALIYVKIK+ D V DIRDP +I+AMYSLEQRL++KEYVTDTFSIADL VQILGR Sbjct: 102 FGGSGSALIYVKIKSPDKVADIRDPTVIKAMYSLEQRLKDKEYVTDTFSIADLAVQILGR 161 Query: 121 LPKNMDEVKFVLNMLPPEARNGLISGDYSSTIIIVNLNREKNQKALVRVYNDIEREIERT 180 LP N++EVKFVLNMLP +ARNGL+S DYSSTIIIV+LNREKNQ+ALVRVYN+I+ EIE++ Sbjct: 162 LPNNIEEVKFVLNMLPEDARNGLVSRDYSSTIIIVSLNREKNQRALVRVYNEIKNEIEKS 221 Query: 181 NFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPLVPL 240 NFP+GVEVVLTGDLGITYKILEMLQNDMNRTMA++GIIV+++LLYFYKSPIRMLVPL+PL Sbjct: 222 NFPEGVEVVLTGDLGITYKILEMLQNDMNRTMAVAGIIVIILLLYFYKSPIRMLVPLIPL 281 Query: 241 IFGVVMTLGFMGLLGIPLDIATTTVGAMIIGMGIDYGVHVTNRYYEERGKGKSLEEAAEE 300 IFGV MTLGFMGLLGIPLDIAT+TVGAMIIGMGIDYGVHVTNRYYEER KG+S EEAAEE Sbjct: 282 IFGVTMTLGFMGLLGIPLDIATSTVGAMIIGMGIDYGVHVTNRYYEERNKGRSPEEAAEE 341 Query: 301 AIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVTPALAILE 360 AI+ETGKALLGAALTTIAGFLALS+SILPSLKRLS+SLVMGLGLAA+NAVIVTPALAILE Sbjct: 342 AISETGKALLGAALTTIAGFLALSLSILPSLKRLSISLVMGLGLAAVNAVIVTPALAILE 401 Query: 361 EEFREKVMKKK-EIIAIGGGKSKISFIFSMLGKAIKRSPWTALLIALIISGVSLYGASKI 419 EEFR K++ KK EII+IGG + K+ FIFS LG IKRSPW ALLIA++ISGVSLYGA+KI Sbjct: 402 EEFRTKILGKKGEIISIGGEEGKLGFIFSRLGLFIKRSPWLALLIAVMISGVSLYGATKI 461 Query: 420 TTEVRLEKMIPTDLPEIQALSDIRSEFGGQDEVTILIKADDVRDPTLVRDILRFEREIKA 479 TTEVRLEKMIP D+PEIQAL+DIRSEFGGQDE+TILIKADDVRDP +VR ILRFERE+KA Sbjct: 462 TTEVRLEKMIPMDMPEIQALTDIRSEFGGQDEITILIKADDVRDPEIVRSILRFEREVKA 521 Query: 480 DSYINNVFETQSIADVVIQKYGYIPQDKEKISEAIEGSSLVSSDYSMTIIKLKGNFMGVT 539 DSYINNVFE++SIADVVI+KYGYIP+DKEKI++A+EGSSLVSSDYS+TI+KLKGNFMGVT Sbjct: 522 DSYINNVFESESIADVVIEKYGYIPEDKEKIAKALEGSSLVSSDYSLTIVKLKGNFMGVT 581 Query: 540 QSEFNRIMEYFERAIQRADFPPGVKVELAGESYLNYVLNDLVNEELGKISTIGTLIVVMV 599 Q +FN+IMEYFE ++RA+FPPGVK ELAGESYLNYVL++LVNEELGKISTIGT+IVV++ Sbjct: 582 QEDFNKIMEYFEEELKRANFPPGVKAELAGESYLNYVLDNLVNEELGKISTIGTIIVVLI 641 Query: 600 VFAIFRRPTVSIAMIMPMFLGALWTIGYMGLAGIPFSQTLAGVVSMIVGLGVDYGMHITH 659 VFAIFRRPTV++AMIMPMFLGALWTIGYMGLAGIPFSQTLAGVVSMIVGLGVDYGMHITH Sbjct: 642 VFAIFRRPTVAVAMIMPMFLGALWTIGYMGLAGIPFSQTLAGVVSMIVGLGVDYGMHITH 701 Query: 660 RFLEELNEGNKTPIITALESVGPGIFVGALTTAGGFLALLSAQLTAIHDFGRVLAVGIFA 719 RFLEEL EGNKTPIITA+ESVGPGI +GALTTAGGFLALL+ +LTAIHDFG+VLAVGIF+ Sbjct: 702 RFLEELKEGNKTPIITAMESVGPGILIGALTTAGGFLALLTGRLTAIHDFGKVLAVGIFS 761 Query: 720 SMFAAYLVTPAILQLEFGRKISKEVRE 746 SM AAYLVTPAILQLEFGRKI KEV+E Sbjct: 762 SMLAAYLVTPAILQLEFGRKI-KEVKE 787 >sp|Q58957|YF62_METJA PUTATIVE MEMBRANE PROTEIN MJ1562 >gi|2128938|pir||A64495 hypothetical protein MJ1562 - Methanococcus jannaschii >gi|1592186|gb|AAB99583.1| (U67596) M. jannaschii predicted coding region MJ1562 [Methanococcus jannaschii] Length = 388 Score = 255 bits (644), Expect = 2e-66 Identities = 128/378 (33%), Positives = 229/378 (59%), Gaps = 8/378 (2%) Query: 1 MLRKIARVIVIYRHS----LAVVTMFLLILSAYGITQLRFETDLSKQLPEDLEAVKSYFT 56 MLR+I + + + + ++ + + + + T ++ +T K LP+D +K+ + Sbjct: 5 MLREILKKVAHFSEQKPFLMLLIILIITVFAGISATNVKSQTAFEKMLPQDNPIIKTLYE 64 Query: 57 LQNEFGGSGSALIYVKIK---NNDNVVDIRDPKIIEAMYSLEQRLREKEYVTDTFSIADL 113 +++EFGG+ I +K+K ++D VVDIRDP++++A+ LE LR + +T S D+ Sbjct: 65 VRDEFGGTDVITICIKLKPSDSSDKVVDIRDPRVLKAIKELEDNLRYVDGITSVSSPVDI 124 Query: 114 MVQIL-GRLPKNMDEVKFVLNMLPPEARNGLISGDYSSTIIIVNLNREKNQKALVRVYND 172 ++Q G +P ++D VK +LN LP + R + + DYS T++ + +QK L+RV +D Sbjct: 125 IIQKNNGIVPNDIDTVKDILNKLPEDKRKRIFNSDYSMTVVNAYTDAGGDQKKLMRVMDD 184 Query: 173 IEREIERTNFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIR 232 + IE T FP GVEV+ TG + + E+++ + T + I +++IL+ +++ P+ Sbjct: 185 VNERIEETPFPPGVEVIATGTPPMRKLMDELMKESQSFTTTVGLIGILIILIIYFRKPLS 244 Query: 233 MLVPLVPLIFGVVMTLGFMGLLGIPLDIATTTVGAMIIGMGIDYGVHVTNRYYEERGKGK 292 ++PL+P++ V+ T G MGLL IPLD+AT +G++I+G+GIDYG+H+ +RY EER KG Sbjct: 245 SIMPLLPVLIAVIWTGGAMGLLDIPLDMATAGIGSLILGLGIDYGIHLMHRYDEERRKGM 304 Query: 293 SLEEAAEEAIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIV 352 +++A E A+ ETG A++ TT+ GFLAL ++ LP + L +G+ + + + Sbjct: 305 PIDKAIETAVVETGTAVMATTATTVVGFLALVLAPLPMMANLGKVCALGISFCMVVVLTL 364 Query: 353 TPALAILEEEFREKVMKK 370 PAL ++EE ++K+ Sbjct: 365 LPALIVIEERHIMPLIKR 382 Score = 202 bits (509), Expect = 1e-50 Identities = 115/359 (32%), Positives = 195/359 (54%), Gaps = 22/359 (6%) Query: 395 KRSPWTALLIALIISGVSLYGASKITTEVRLEKMIPTDLPEIQALSDIRSEFGGQDEVTI 454 ++ P+ LLI LII+ + A+ + ++ EKM+P D P I+ L ++R EFGG D +TI Sbjct: 18 EQKPFLMLLIILIITVFAGISATNVKSQTAFEKMLPQDNPIIKTLYEVRDEFGGTDVITI 77 Query: 455 LIKAD---------DVRDPTLVRDILRFEREIKADSYINNVFETQSIADVVIQKY-GYIP 504 IK D+RDP +++ I E ++ Y++ + S D++IQK G +P Sbjct: 78 CIKLKPSDSSDKVVDIRDPRVLKAIKELEDNLR---YVDGITSVSSPVDIIIQKNNGIVP 134 Query: 505 QDKEKISEAI------EGSSLVSSDYSMTIIKLKGNFMGVTQSEFNRIMEYFERAIQRAD 558 D + + + + + + +SDYSMT++ + G Q + R+M+ I+ Sbjct: 135 NDIDTVKDILNKLPEDKRKRIFNSDYSMTVVNAYTD-AGGDQKKLMRVMDDVNERIEETP 193 Query: 559 FPPGVKVELAGESYLNYVLNDLVNEELGKISTIGTLIVVMVVFAIFRRPTVSIAMIMPMF 618 FPPGV+V G + ++++L+ E +T+G + +++++ FR+P SI ++P+ Sbjct: 194 FPPGVEVIATGTPPMRKLMDELMKESQSFTTTVGLIGILIILIIYFRKPLSSIMPLLPVL 253 Query: 619 LGALWTIGYMGLAGIPFSQTLAGVVSMIVGLGVDYGMHITHRFLEELNEGN--KTPIITA 676 + +WT G MGL IP AG+ S+I+GLG+DYG+H+ HR+ EE +G I TA Sbjct: 254 IAVIWTGGAMGLLDIPLDMATAGIGSLILGLGIDYGIHLMHRYDEERRKGMPIDKAIETA 313 Query: 677 LESVGPGIFVGALTTAGGFLALLSAQLTAIHDFGRVLAVGIFASMFAAYLVTPAILQLE 735 + G + TT GFLAL+ A L + + G+V A+GI M + PA++ +E Sbjct: 314 VVETGTAVMATTATTVVGFLALVLAPLPMMANLGKVCALGISFCMVVVLTLLPALIVIE 372 >gi|11498828 conserved hypothetical protein [Archaeoglobus fulgidus] >gi|7430104|pir||D69403 conserved hypothetical protein AF1229 - Archaeoglobus fulgidus >gi|2649351|gb|AAB90013.1| (AE001019) conserved hypothetical protein [Archaeoglobus fulgidus] Length = 750 Score = 231 bits (582), Expect = 3e-59 Identities = 193/758 (25%), Positives = 359/758 (46%), Gaps = 49/758 (6%) Query: 1 MLRKIARVIVIYRHSLAVVTMFLLILSAYGITQLRFETDLSKQLPEDLEAVKSYFTLQNE 60 +L ++AR I + + +LILSA+ + + +D + Y Q + Sbjct: 5 LLDRVARFIARRPGFVISIISIILILSAFSAQNVGLTSGTESMFSKDNVIYRQYKLYQKD 64 Query: 61 FGGSGSALIYVKIKNNDNVVDIRDPKIIEAMYSLEQRLREKEYVTDTFSIADLMVQILGR 120 FG G+ ++V IK +D V + ++ + + L++R+ E E V+ S A ++ + G Sbjct: 65 FG-VGADQLFVLIKGDDVV----NSEVYQYLLDLQKRIEEIEGVSSVVSPASIVSSLYGG 119 Query: 121 LPKNMDEVKFVLNMLPPEARNGLISGDYSSTIIIVNLNREKNQKALVRVYNDIEREIERT 180 LP + ++ ++ + + + ++I+ L + K + ++E+ I T Sbjct: 120 LPSDESKISIATSLYASD-----LVPKPTLAMMIIQLGTADDTKQ-EEIAIEVEKVISFT 173 Query: 181 NFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRM----LVP 236 N P G+ + LTG ++Y+I + TM +S I++VL+L + +R +P Sbjct: 174 NPPHGLVLQLTGGPALSYQIEREIGKSFGITMMVSIILMVLLLFLTFSGAVRKKYTAFLP 233 Query: 237 LVPLIFGVVMTLGFMGLLGIPLDIATTTVGAMIIGMGIDYGVHVTNRYYEERGKGKSLEE 296 LV + V + G M +LGIPL T M+IG+ I+YG + NRY EER +G+ +++ Sbjct: 234 LVISVMSVTVVYGLMPILGIPLSEHTNGALPMLIGLAIEYGAQLQNRYEEERREGRDVDD 293 Query: 297 AAEEAIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVTPAL 356 A +I TG A++ A +TT+ GF+++ +P++ + + +GL +A L + PA+ Sbjct: 294 AVVISITRTGLAIVMALITTVIGFMSMLAPGMPAMAQFGIISSLGLIVAYLLTLTFLPAV 353 Query: 357 AILEEEFRE-KVMKKKEIIAIGGGKSKISFIFSMLGKAIKRSPWTALLIALIISGVSLYG 415 L + + + K K++E ++G + +S I ++ P L+ A II LY Sbjct: 354 LKLIDHWNDAKEQKREEEKSVGTLERSLSAISTLTA----TRPVGILVAASIIVLFGLYA 409 Query: 416 ASKITTEVRLEKMIPTDLPEIQALSDIRSEFGGQDEVTILIKADDVRDPTLVRDILRFER 475 A +I E K +P DL +Q +I GGQ T++++ D++ TL + Sbjct: 410 APQIGLETNYNKYVPQDLTAMQRFKEIERLVGGQATYTLVLEVDELNAETLKEIDELSKY 469 Query: 476 EIKADSYINNVFETQSIADVVIQKYGY--IPQDKEKISEAIEGSSLVSSDYSMTII--KL 531 ++ + I + + V + YG+ +P+ ++ + + S+L + S I ++ Sbjct: 470 IVEKEELIYDYSSITKLISEVRKAYGFEGLPESDAELMQIL--SALPQEEVSRYISGGQI 527 Query: 532 KGNFMGVTQSEFNRIMEYFERAIQRADFPPGVKVELAGESYLNYVL-NDLVNEELGKIST 590 +F S+ I + ++I R VE G S YV ++ E+G++ T Sbjct: 528 AVHFSSNADSQDEYISTH--KSIVR-------DVEFFGWSGGYYVTGGPVIYGEMGRLMT 578 Query: 591 IGT--------LIVVMVVFAIFR--RPTVSIAMIMPMFLGALWTIGYMGLAGIPFSQTLA 640 G +++M++ A++R R V + + +GA+ TI M L G + Sbjct: 579 SGQTTMTVVAYALIIMLLLAVYRSIRKAVVPLIAITSVIGAMNTI--MFLTGTKQTMISI 636 Query: 641 GVVSMIVGLGVDYGMHITHRFLEELNEGNKTPII-TALESVGPGIFVGALTTAGGFLALL 699 + S+ +GLG+D+ +H+ R+ EE + + +E G I ALT AGGF +L+ Sbjct: 637 ALNSITLGLGIDFSIHVLERYFEERAAFSPVEAVRRTIERTGKAITTSALTMAGGFGSLM 696 Query: 700 SAQLTAIHDFGRVLAVGIFASMFAAYLVTPAILQLEFG 737 + + +FG + V I S+ AA V PA L L G Sbjct: 697 FSTFPIMQNFGFIALVAILFSLLAALTVVPAFLMLTEG 734 Score = 115 bits (285), Expect = 2e-24 Identities = 87/360 (24%), Positives = 174/360 (48%), Gaps = 23/360 (6%) Query: 16 LAVVTMFLLILSAYGITQLRFETDLSKQLPEDLEAVKSYFTLQNEFGGSGSALIYVKIKN 75 + V +++ Y Q+ ET+ +K +P+DL A++ + ++ GG + + ++ Sbjct: 395 ILVAASIIVLFGLYAAPQIGLETNYNKYVPQDLTAMQRFKEIERLVGGQATYTLVLE--- 451 Query: 76 NDNVVDIRDPKIIEAMYSLEQRLREKE-YVTDTFSIADLMVQI-----LGRLPKNMDEVK 129 VD + + ++ + L + + EKE + D SI L+ ++ LP++ E+ Sbjct: 452 ----VDELNAETLKEIDELSKYIVEKEELIYDYSSITKLISEVRKAYGFEGLPESDAELM 507 Query: 130 FVLNMLPPEARNGLISGDYSSTIIIVNLNREKNQKALVRVYNDIEREIERTNFPQGVEVV 189 +L+ LP E + ISG + N + +Q + + I R++E + G V Sbjct: 508 QILSALPQEEVSRYISGGQIAVHFSSNAD---SQDEYISTHKSIVRDVEFFGWSGGYYV- 563 Query: 190 LTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPLVPL--IFGVVMT 247 TG I ++ ++ + ++ +++++LL Y+S + +VPL+ + + G + T Sbjct: 564 -TGGPVIYGEMGRLMTSGQTTMTVVAYALIIMLLLAVYRSIRKAVVPLIAITSVIGAMNT 622 Query: 248 LGFMGLLGIPLDIATTTVGAMIIGMGIDYGVHVTNRYYEERGKGKSLEEAAEEAIAETGK 307 + F L G + + + ++ +G+GID+ +HV RY+EER +E A I TGK Sbjct: 623 IMF--LTGTKQTMISIALNSITLGLGIDFSIHVLERYFEERAAFSPVE-AVRRTIERTGK 679 Query: 308 ALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVTPALAILEEEFREKV 367 A+ +ALT GF +L S P ++ ++ + + L A+ V PA +L E ++ Sbjct: 680 AITTSALTMAGGFGSLMFSTFPIMQNFGFIALVAILFSLLAALTVVPAFLMLTEGIEARI 739 >gi|11498071 conserved hypothetical protein [Archaeoglobus fulgidus] >gi|7430103|pir||C69307 conserved hypothetical protein AF0459 - Archaeoglobus fulgidus >gi|2650170|gb|AAB90778.1| (AE001073) conserved hypothetical protein [Archaeoglobus fulgidus] Length = 736 Score = 203 bits (512), Expect = 5e-51 Identities = 170/683 (24%), Positives = 314/683 (45%), Gaps = 54/683 (7%) Query: 69 IYVKIKNNDNVVDIRDPKIIEAMYSLEQRLREKEYVTDTFSIADLMVQILGRLPKNMDEV 128 +Y+ +K D + ++E M SL++ L ++ V T S A ++ +LG +P + + V Sbjct: 78 VYIIVKAED----VLSRDVMEYMLSLQKVLEGRDGVVSTSSPASILRDVLGDIPDSEELV 133 Query: 129 KFVLNMLPPEARNGLISGDYSSTIIIVNLNREKNQKALVRVYNDIEREIERTNFPQGVEV 188 L + + S +I V + +N + L+ + +IER ++ + P GV V Sbjct: 134 GETAERLAKS-----LLPERSFALISVQIESMENDR-LMELAEEIERILQFVSPPPGVVV 187 Query: 189 VLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIR----MLVPLVPLIFGV 244 +TG + Y+I + ++ D+ RT I+ + ++ +L+ + +R +L PL+ + V Sbjct: 188 DVTGGAVLMYQIAKAVEEDVYRTFFIASVTMIAVLVAVFSGVVRSKLTVLFPLIVSLMSV 247 Query: 245 VMTLGFMGLLGIPLDIATTTVGAMIIGMGIDYGVHVTNRYYEERGKGKSLEEAAEEAIAE 304 + G + LLG+ + + ++IG+ IDY + NRY EER G+ ++EA EEA+ Sbjct: 248 AVMAGLLPLLGLQMTEYNSATIPILIGLAIDYAAQLQNRYEEERRGGREVDEALEEALNH 307 Query: 305 TGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVTPALAILEEEFR 364 T L A TT+ GF ++ +PSL S L +GL A L + P+L L + Sbjct: 308 TRFPLFMAMATTVIGFASMCAPGIPSLFWFSFLLSVGLITAFLLSNTFLPSLLKLSDR-- 365 Query: 365 EKVMKKKEIIAIGGGKSKIS-----FIFSMLGKAIKRSPWTALLIALIISGVSLYGASKI 419 GG + IS + + + K + L + LI+ V Y ++ + Sbjct: 366 ------------GGREESISPGILEKLLTTIAKVTIANSRKILALTLILIVVGAYASTHV 413 Query: 420 TTEVRLEKMIPTDLPEIQALSDIRSEFGGQDEVTILIKADDVRDPTLVRDILRFEREIKA 479 E K P DLP + +I + Q +++ + + +++ E K Sbjct: 414 ELETNRRKYAPPDLPALVKFEEIERKVSPQYVYALVLSTERID----AESVVKAEELAKY 469 Query: 480 DSYINNVFETQSIADVVIQKYGYIPQDKEKISEAIEGSSLVSSDYSMTIIKLKGNFMGV- 538 S +++ S+ + + YG IP E S+AI+ +L S YS I GN + V Sbjct: 470 ISSREEIYDYDSLGKTLEEYYGAIP--AESFSKAID--ALPKSIYSRFI---SGNQLAVY 522 Query: 539 ------TQSEFNRIMEYFERAIQRADFPPGVKVELAGESYLNYVLNDLVNEELGKISTIG 592 T+ E ++M E ++ ++ + G + L++++ L ++ + Sbjct: 523 FYTNTQTEEEVEKMMRSIENDLRFLEWDGDYYI--TGFPVILGHLSEVLFSSLNLMTLVA 580 Query: 593 TLIVVMVVFAIFRRPTVSIAMIMPMFLGALWTIGYMGLAGIPFSQTLAGVVSMIVGLGVD 652 L++V + +R +I ++ + + M L GI + + S+++G+G+D Sbjct: 581 YLLIVTFLLLAYRSVVRAIIPLISISVAVASMNVCMLLMGIKQTTISIALNSIVLGMGID 640 Query: 653 YGMHITHRFLEELNE-GNKTPIITALESVGPGIFVGALTTAGGFLALLSAQLTAIHDFGR 711 Y +HIT R+ EE + G + + +E G + ALTTAGGF AL + + +FG Sbjct: 641 YSIHITERYFEERGKFGVEESVKRTVERTGKAVLTSALTTAGGFGALYFSTFPVLSNFGI 700 Query: 712 VLAVGIFASMFAAYLVTPAILQL 734 + + I S+ AA PA+L L Sbjct: 701 LAFIAIIFSLLAATSAVPALLIL 723 Score = 146 bits (364), Expect = 1e-33 Identities = 97/367 (26%), Positives = 178/367 (48%), Gaps = 17/367 (4%) Query: 1 MLRKIARVIVIYRHSLAVVTMFLLILSAYGITQLRFETDLSKQLPEDLEAVKSYFTLQNE 60 +L IA+V + + +T+ L+++ AY T + ET+ K P DL A+ + ++ + Sbjct: 380 LLTTIAKVTIANSRKILALTLILIVVGAYASTHVELETNRRKYAPPDLPALVKFEEIERK 439 Query: 61 FGGSGSALIYVKIKNNDNVVDIRDPKIIEAMYSLEQRLREKEYVTDTFSIADLMVQILGR 120 +Y + + + + D + + L + + +E + D S+ + + G Sbjct: 440 VSPQ---YVYALVLSTERI----DAESVVKAEELAKYISSREEIYDYDSLGKTLEEYYGA 492 Query: 121 LPKNMDEVKFVLNMLPPEARNGLISGDYSSTIIIVNLNREKNQKALVRVYNDIEREIERT 180 +P + ++ LP + ISG+ + N E+ + ++R + R +E Sbjct: 493 IPA--ESFSKAIDALPKSIYSRFISGNQLAVYFYTNTQTEEEVEKMMRSIENDLRFLEWD 550 Query: 181 NFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPLVPL 240 + +TG I + E+L + +N ++ +++V LL Y+S +R ++PL+ + Sbjct: 551 G-----DYYITGFPVILGHLSEVLFSSLNLMTLVAYLLIVTFLLLAYRSVVRAIIPLISI 605 Query: 241 IFGVVMTLGFMGLLGIPLDIATTTVGAMIIGMGIDYGVHVTNRYYEERGKGKSLEEAAEE 300 V M L+GI + + ++++GMGIDY +H+T RY+EERGK +EE+ + Sbjct: 606 SVAVASMNVCMLLMGIKQTTISIALNSIVLGMGIDYSIHITERYFEERGKF-GVEESVKR 664 Query: 301 AIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVTPALAILE 360 + TGKA+L +ALTT GF AL S P L + + + + L A PAL IL Sbjct: 665 TVERTGKAVLTSALTTAGGFGALYFSTFPVLSNFGILAFIAIIFSLLAATSAVPALLILY 724 Query: 361 EE--FRE 365 E+ FRE Sbjct: 725 EKNYFRE 731 >gb|AAG19780.1| (AE005063) Vng1476c [Halobacterium sp. NRC-1] Length = 746 Score = 173 bits (435), Expect = 5e-42 Identities = 167/680 (24%), Positives = 293/680 (42%), Gaps = 53/680 (7%) Query: 81 DIRDPKIIEAMYSLEQRLREKEYVTDTFSIADLMVQILGRLPKNMDEVKFVLNMLPPEAR 140 DI +P IEA+ ++R+ + + V S AD + GR+P + +++ V+ Sbjct: 75 DITEPSAIEAIDRYDRRMSQTQDVYAVRSPADQVRAAYGRIPDSKSKIESVIG------- 127 Query: 141 NGLISGDYSSTIIIVNLNREKNQKALVRVYNDIEREIERTNFPQGVEVVLTGDLGITYKI 200 S DY++ I + + + Q+ +Y + + FP V +TGD + ++ Sbjct: 128 ----SPDYTTIQIATDTDLTQQQQR--PIYTEAVSTSDWARFPASVTATVTGDAAFSAQL 181 Query: 201 LEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPLVPLIFGVVMTLGFMGLLGIPLDI 260 ++Q + + ++ ++V+ L + ++ L+P+V + GV+ T G +G GIP Sbjct: 182 STVIQQSTQKLLGLAVGLMVIALFFLFRGVRLRLLPIVAVFVGVIYTFGAIGYGGIPNST 241 Query: 261 ATTTVGAMIIGMGIDYGVHVTNRYYEERGKGKSLEEAAEEAIAETGKALLGAALTTIAGF 320 T+ V ++IG+GIDY V R YEE + EA A+ G +L A L GF Sbjct: 242 MTSAVFPILIGLGIDYSVQFHER-YEEELETHPPREALPNALGGVGPPVLIAMLAAALGF 300 Query: 321 LALSISI-LPSLKRLSVSLVMGLGLA-ALNAVIVTPALAILEEEFREKVMKKKEIIAIGG 378 A +S P++ + + ++G+ L A +++ L I + + A GG Sbjct: 301 GATWVSTSSPAIIWFAQTSILGVLLTYAAGILVLLAGLTIYIRRWGD----DSPAAADGG 356 Query: 379 G----------KSKISFIFSMLGKA---IKRSPWTALLIALIISGVSLYGASKITTEVRL 425 S+I + S LG+ + P T L IAL++SGV AS + T Sbjct: 357 DPEAAHAEVDEDSRIGLVGSTLGRTSRILASHPMTVLAIALVLSGVGFQVASSLGTLADT 416 Query: 426 EKMIPTDLPEIQALSDIRSEFGGQDEVT--ILIKADDVRDPTLVRDILRFEREIKADSYI 483 E+ IP DLP L RS+ GG + +L+ ++ P + LR+ + + Sbjct: 417 EEFIPQDLPAYVDLQQFRSQTGGGTSTSYDVLVTGTHLKHP----ETLRWMDGLNDVATQ 472 Query: 484 NNVFETQSIADVVIQKY--GYIPQDKEKISEAI-----EGSSLVSSDYSMTIIKLKGNFM 536 + E +++Y G IP+ + + E +D I M Sbjct: 473 APLVEGVDTPAGAVKQYNGGEIPRTTSGVERVLAQMPTEQRQRYYNDGRAHITVASPQDM 532 Query: 537 GVTQSEFNRIMEYFERAIQRADFPPGVKVELAGESYLNY-VLNDLVNEELGKISTIGTLI 595 T + +E + ++ ++ PPGV E+ G S + + D +N + +G L Sbjct: 533 --TTGQVLSFLENSQESLDYSNPPPGVTAEVTGTSSIAVPSIIDQINSR-NTTTGLGILF 589 Query: 596 VVMVVFAIFRRPTVSIAMIMPMFLGALWTIGYMGLAGIPFSQTLAGVVSMIVGLGVDYGM 655 V ++ +R ++A ++PM W YM IP S A + +M VG+G +Y + Sbjct: 590 VFALLGLYYRDLVKAVAPLVPMVFVIGWQNIYMLALDIPVSPLGASLGAMTVGIGAEYTI 649 Query: 656 HITHRFLEELNE---GNKTPIITALESVGPGIFVGALTTAGGFLALLSAQLTAIHDFGRV 712 + R+ EE G + A VG I V +TT GF AL+ + + FG + Sbjct: 650 IVMERYYEEKQHNGYGRLDAVEIAASRVGKAITVSGMTTVFGFSALILSPFPVLSSFGFL 709 Query: 713 LAVGIFASMFAAYLVTPAIL 732 IF ++ A+ P L Sbjct: 710 TVGVIFLTLIASLATLPPTL 729 Score = 121 bits (300), Expect = 3e-26 Identities = 97/359 (27%), Positives = 171/359 (47%), Gaps = 19/359 (5%) Query: 382 KISFIFSMLGKAIKRSPWTALLIALIISGVSLYGASKITTEVRLEKMIPTDLPEIQALSD 441 K+ F+ +G ++ P LLIA ++ V++ GA++IT+ + + ++ P +A SD Sbjct: 3 KLRSAFASIGDRVQARPVATLLIAGLLILVAIGGAAQITSVTGDDAFVGSN-PTYEAFSD 61 Query: 442 IRSEFGGQDEVTILIKADDVRDPTLVRDILRFEREIKADSYINNVFETQSIADVVIQKYG 501 + +LI+ D + +P+ + I R++R + S +V+ +S AD V YG Sbjct: 62 SFDH----GNIAVLIRGD-ITEPSAIEAIDRYDRRM---SQTQDVYAVRSPADQVRAAYG 113 Query: 502 YIPQDKEKISEAIEGSSLVSSDYSMTIIKLKGNFMGVTQSEFNRIMEYFERAIQRADFPP 561 IP K KI I S DY+ I + +TQ + I A FP Sbjct: 114 RIPDSKSKIESVIG-----SPDYTTIQIATDTD---LTQQQQRPIYTEAVSTSDWARFPA 165 Query: 562 GVKVELAGESYLNYVLNDLVNEELGKISTIGTLIVVMVVFAIFRRPTVSIAMIMPMFLGA 621 V + G++ + L+ ++ + K+ + ++V+ +F +FR + + I+ +F+G Sbjct: 166 SVTATVTGDAAFSAQLSTVIQQSTQKLLGLAVGLMVIALFFLFRGVRLRLLPIVAVFVGV 225 Query: 622 LWTIGYMGLAGIPFSQTLAGVVSMIVGLGVDYGMHITHRFLEEL-NEGNKTPIITALESV 680 ++T G +G GIP S + V +++GLG+DY + R+ EEL + + AL V Sbjct: 226 IYTFGAIGYGGIPNSTMTSAVFPILIGLGIDYSVQFHERYEEELETHPPREALPNALGGV 285 Query: 681 GPGIFVGALTTAGGFLAL-LSAQLTAIHDFGRVLAVGIFASMFAAYLVTPAILQLEFGR 738 GP + + L A GF A +S AI F + +G+ + A LV A L + R Sbjct: 286 GPPVLIAMLAAALGFGATWVSTSSPAIIWFAQTSILGVLLTYAAGILVLLAGLTIYIRR 344 Score = 103 bits (255), Expect = 6e-21 Identities = 90/358 (25%), Positives = 160/358 (44%), Gaps = 15/358 (4%) Query: 10 VIYRHSLAVVTMFLLILSAYGI---TQLRFETDLSKQLPEDLEAVKSYFTLQNEFGGSGS 66 ++ H + V+ + L+LS G + L D + +P+DL A +++ GG S Sbjct: 384 ILASHPMTVLAI-ALVLSGVGFQVASSLGTLADTEEFIPQDLPAYVDLQQFRSQTGGGTS 442 Query: 67 ALIYVKIKNNDNVVDIRDPKIIEAMYSLEQRLREKEYVTDTFSIADLMVQILG-RLPKNM 125 V + ++ P+ + M L + V + A + Q G +P+ Sbjct: 443 TSYDVLVTGTH----LKHPETLRWMDGLNDVATQAPLVEGVDTPAGAVKQYNGGEIPRTT 498 Query: 126 DEVKFVLNMLPPEARNGLISGDYSSTIIIVNLNREKNQKALVRVYNDIEREIERTNFPQG 185 V+ VL +P E R + + I V ++ ++ + + ++ +N P G Sbjct: 499 SGVERVLAQMPTEQRQRYYNDGRAH--ITVASPQDMTTGQVLSFLENSQESLDYSNPPPG 556 Query: 186 VEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPLVPLIFGVV 245 V +TG I + N N T + + V +L +Y+ ++ + PLVP++F + Sbjct: 557 VTAEVTGTSSIAVPSIIDQINSRNTTTGLGILFVFALLGLYYRDLVKAVAPLVPMVFVIG 616 Query: 246 MTLGFMGLLGIPLDIATTTVGAMIIGMGIDYGVHVTNRYYEERG-KGKSLEEAAEEAIAE 304 +M L IP+ ++GAM +G+G +Y + V RYYEE+ G +A E A + Sbjct: 617 WQNIYMLALDIPVSPLGASLGAMTVGIGAEYTIIVMERYYEEKQHNGYGRLDAVEIAASR 676 Query: 305 TGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVT--PALAILE 360 GKA+ + +TT+ GF AL +S P L L +G+ L A + T P L +L+ Sbjct: 677 VGKAITVSGMTTVFGFSALILSPFPVLSSFGF-LTVGVIFLTLIASLATLPPTLVVLD 733 >pir||D70131 conserved hypothetical integral membrane protein BB0252 - Lyme disease spirochete >gi|2688146|gb|AAB91494.1| (AE001135) conserved hypothetical integral membrane protein [Borrelia burgdorferi] Length = 767 Score = 145 bits (363), Expect = 1e-33 Identities = 165/768 (21%), Positives = 345/768 (44%), Gaps = 73/768 (9%) Query: 13 RHSLAVVTMFLLILSAYG--ITQLRFETDLSKQLPEDLEAVKSYFTLQNEFGGSGSALIY 70 R+ + T+F+LI G + L+F+ ++ K +P+ E + S S L Sbjct: 9 RYKGIIFTIFILITIFLGFFLKNLKFDANILKLIPKTKETESLI-----DIDKSNSLLST 63 Query: 71 VKI-KNNDNVVDIRDPKIIEAMYSLEQRLRE--KEYVTDTFSIADLMVQILGRLPKNMDE 127 + I ++ N+ + ++ + I ++ S ++ + VT FS + + K+++E Sbjct: 64 IVIFQDKKNIFNKKNFETINSVISEITKILKVSPNAVTSIFSYFPQFKKEI-YTDKDIEE 122 Query: 128 VKFVLNMLPPEARNGLISGDYSSTIIIVNLNREKNQ----KALVRVYNDIEREIERTNFP 183 +K + P L G+ + I + + E +Q + L +++E+ I++ Sbjct: 123 IKSKIKSTPFVKNTFL--GNSENLIYFIIIPSESDQINFSRNLKTELDEMEKTIKKYE-T 179 Query: 184 QGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPLVPLIFG 243 +++ LTGDL + KIL + D ++ +V++ L K+ I L+P+ + Sbjct: 180 DDLKLYLTGDLIVREKILNYMVEDFKILGPLATFVVIISLYLIIKNLIGALIPIFIALLS 239 Query: 244 VVMTLGFMGLLGIPLDIATTTVGAMIIGMGIDYGVHVTNRYYEERGKGKSLEEAAEEAIA 303 ++ T G GL+ P+ + T++ ++I +G VH+ N ++ K + +E+ + I Sbjct: 240 LIWTFGIKGLVQSPITVPETSMIVLLISIGCANAVHIINEIFKLIKKEQLSKESIKATIK 299 Query: 304 ETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVTPALAILEEEF 363 + +L + TT GFL+L+ S + + K + + + +G+ ++ + ++ V P + L Sbjct: 300 KLKTPILLTSFTTAFGFLSLTTSSINAYKTMGIFMSIGVIISMIISLTVLPGIITLIPFA 359 Query: 364 REKVMKKKEIIAIGGGKSKISF------IFSMLGKAIKRSPWTALLIALIISGVSLYGAS 417 ++K +K++ + +KISF + + + K+I + +T+ ++ LII G+S G Sbjct: 360 KKKSFEKEKENKL----NKISFLERLAKLNTQITKSILKRKYTSSIMVLIILGISFVGLL 415 Query: 418 KITTEVRLEKMIPTDLPEIQALSDIRSEFGGQDEVTILI----------KADDVRDPTLV 467 KI + + L+ ++ E GG I I KA + D L+ Sbjct: 416 KIEINFDEKDYFKESTSVKKTLNLMQKEMGGISIFKIEIEGRPGEFKNAKAMQILD--LI 473 Query: 468 RDILRFEREIKADSYINNVFETQSIADVVIQKYGY-IPQDK---EKISEAIEGSS----- 518 D L S IN + + + Y +P++K K+ I+ S Sbjct: 474 TDKLDAFSAKTQSSSINGILKFTNFKIKKESPLEYKLPENKIILNKLINLIDKSDWTKDN 533 Query: 519 ---LVSSDYSM--TIIKLKGNFM-GVTQSE---FNRIMEYFERAIQRADFPPGVKVELAG 569 ++ D+S+ I++++ N G+ + E N I EY + K +G Sbjct: 534 KRMYINDDWSLISIIVRIEDNSTEGIKKFEKYAINTINEYMKNN----------KYHFSG 583 Query: 570 ESYLNYVLNDLVNEE-LGKISTIGTLIVVMVVFAIFRRPTVSIAMIMPMFLGALWTIGYM 628 + +V E+ + I+T+G++ ++++ F F+ I + +P+ M Sbjct: 584 VYDKVLIAKTMVKEQVINIITTLGSITLLLMFF--FKSIKTGIIIAIPVAWSVFLNFAVM 641 Query: 629 GLAGIPFSQTLAGVVSMIVGLGVDYGMHITHRFL--EELNEGNKTPIITALESVGPGIFV 686 L GI + A + S+ +G+GVDY +H + F+ + N+ KT ++ ++ +V GIF Sbjct: 642 RLFGITLNPATATIASVSMGVGVDYSIHFFNTFILQYQKNQIYKTALLESIPNVFNGIFA 701 Query: 687 GALTTAGGFLALLSAQLTAIHDFGRVLAVGIFASMFAAYLVTPAILQL 734 +++ GFL L + I G ++A + + A+ + P ++ L Sbjct: 702 NSISVGIGFLTLTFSSYKIISTLGAIIAFTMLTTSLASLTLLPLLIYL 749 >pir||E72272 conserved hypothetical protein - Thermotoga maritima (strain MSB8) >gi|4981852|gb|AAD36368.1|AE001784_10 (AE001784) conserved hypothetical protein [Thermotoga maritima] Length = 694 Score = 141 bits (352), Expect = 3e-32 Identities = 166/755 (21%), Positives = 329/755 (42%), Gaps = 86/755 (11%) Query: 1 MLRKIARVIVIYRHSLAVVTMFLLILSAYGITQLRFETDLSKQLPEDLEAVKSYFTLQNE 60 M K + R + + + + IL+ +G+ +L F T+ S +P+ + Y + Sbjct: 1 MFEKYTSFVFKNRKRIFALVLVINILALFGLFRLHFTTEFSILMPQKSHQKEIYDRMNTI 60 Query: 61 FGGSGSALIYVKIKNNDNVVDIRDPKIIEAMYSLEQRLREKEYVT---DTFSIADLMVQI 117 F + VK+ N D + K+ E L K +T + F + +V+ Sbjct: 61 FKSGEQLAVMVKM-NTDPLSREGLNKVFEIKERLSSIEGVKTVITPVPEKFPVGFRLVET 119 Query: 118 LGRLPKNMDE-------VKFVLNMLPPEARNGLISGDYSSTIIIV--NLNREKNQKALVR 168 G K ++ VK +LN+ + G Y+ +I+ ++ EK +K L Sbjct: 120 KGMAEKEYEDFLSYVQSVKDLLNVKKTD------DGYYALFMILPEESVPPEKIEKVL-- 171 Query: 169 VYNDIEREIERTNFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYK 228 +D E + T + + I +L M+ + VVL+L F Sbjct: 172 --SDYEHYLSGTQYLEDQ---------IFRYLLFMI-------FTLPPFAVVLLLNVFRV 213 Query: 229 SPIRM---LVPLVPLIFGVVMTLGF-MGLLGIPLDIATTTVGAMIIGMGIDYGVHVTNRY 284 R + L+P F + TLG MG G L I T V I MG G+H + + Sbjct: 214 QLGRFKYAIFSLIPAGFAALWTLGIVMGWFGQDLSIITFLVPIFTIVMGSADGLHFVSHF 273 Query: 285 YEERGKGKSLEEAAEEAIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGL 344 E + +G++ A + + G+A++ LTT+AGFL+ S+K++ V +G+GL Sbjct: 274 LERKREGETTFNAVKNTLESVGRAMILTTLTTMAGFLSFLTLNSESMKQMGVLASIGIGL 333 Query: 345 AALNAVIVTPALAILEEEFREKVMKKKEIIAIGGGKSKISFIFSMLGKAIKRSPWTALLI 404 A ++ IV P + E+ K+K S +F + K KR AL++ Sbjct: 334 AGVSTWIVLPVILSRVEKVEP--------------KNKESGVFRVFQKLSKR----ALVV 375 Query: 405 ALIISGVSLYGASKITTEVRLEKMIPTDLPEIQALSDIRSEFGGQDEVTILIKADDVRDP 464 ++ + L G + ++ + K+ + + + I FG V IL +++++ DP Sbjct: 376 TIVSVLIFLPGLFFLKADLNILKLYKSYTRVRKNVEKIEEVFGRALPVYILFESENLFDP 435 Query: 465 TLVRDILRFEREIKADSYINNVFETQSIADVVIQKYGYIPQDK---EKISEAIEGSSLVS 521 + + +L E ++K + F+ S+ D++ + + ++K + ++ A+ L+ Sbjct: 436 SFAQKVLSMEEDLKKEG-----FDAFSMYDIISKLNERLFKEKGYPKILARALILKRLLP 490 Query: 522 SDYSMTIIKLKGNFMGVTQSEFNR-IMEYFERAIQRADFPPGVKVELAGESYLNYVLND- 579 +Y+ ++ V ++ +R I+ E +++ F ++ G Y+ +ND Sbjct: 491 DEYTENLVSGNTGRAFVFLNDLDREILVKVENVVEKHGF------QVTGIPYIIKEMNDS 544 Query: 580 LVNEELGKISTIGTLIVVMVVFAIFRRPTVSIA-MIMPMFLGALWTIGYMGLAGIPFSQT 638 +V ++L +S + +V ++ +F+R + A I+P+ + + G+MGL+GIP + Sbjct: 545 IVPQQL--LSVFLAISMVFLLLVLFQRSFLYPAKAIVPVGISLVSLFGFMGLSGIPLNLI 602 Query: 639 LAGVVSMIVGLGVDYGMHITHRFLEELNEGNKTPIITALESVGPGIFVGALTTAGGFLAL 698 A + +++G+G+DY +H+T F + KT I + + A + G AL Sbjct: 603 TANMAGIVIGVGIDYAIHVTELF-RYYGDIEKTVRIASTP-----VLANAFGLSIGLSAL 656 Query: 699 LSAQLTAIHDFGRVLAVGIFASMFAAYLVTPAILQ 733 + + T ++ V + S F + ++ P +L+ Sbjct: 657 ILSPFTFHTYLVAIMWVTMTVSSFMSLVILPKLLE 691 >sp|O54101|MMLB_STRCO PUTATIVE MEMBRANE PROTEIN SC10A5.10C >gi|7480675|pir||T34577 probable export protein - Streptomyces coelicolor >gi|2815318|emb|CAA16442.1| (AL021529) SC10A5.10c, probable export protein, len: 847 aa; si milar to eg. S. coelicolor actinorhodin antibiotic export p rotein TR:Q53902 (EMBL:M64683) ORF2 (ACTII) (711 aa), fasta scores; opt: 705 z-score: 1126.2 E(): 0, 35.4% identity in 746 aa ov> Length = 847 Score = 115 bits (285), Expect = 2e-24 Identities = 152/632 (24%), Positives = 259/632 (40%), Gaps = 69/632 (10%) Query: 128 VKFVLNMLPPEARNGLISGDYSSTIIIVNLNREKNQKALVRVYNDIEREIERTNFPQGVE 187 V V + P+A L+S D + ++IV + + ++ +++ P + Sbjct: 111 VSVVSTVTAPDAAAELVSQDRGAQLVIVPMEGSPSDESFQNAVDEVRALASDRAGP--AD 168 Query: 188 VVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPLVPLIFGVVM- 246 V +TG GI +++ + + ++V++ILL Y+SP+ LVPL L GV M Sbjct: 169 VAVTGPAGIATDTVKVFSGGDKVLLLATVVLVLIILLAIYRSPLMALVPL--LAVGVAMR 226 Query: 247 ---TLGFMGLLGIPLDIATTTVGAMII---GMGIDYGVHVTNRYYEERGKGKSLEEAAEE 300 TLG + + +++ T M + G+G DY + +T RY E A + Sbjct: 227 VAETLGAILADAGVITVSSQTASIMTVLLFGVGTDYALIITARYRETLLDEPDRARAMQA 286 Query: 301 AIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVTPALAIL- 359 A+ T +++L +A T + AL +++ P+L L +G+ + AL A PAL +L Sbjct: 287 AVRRTAESVLASASTIVLAMFALLVAVSPALHGFGPYLALGVAVMALVAFTFIPALVLLL 346 Query: 360 -EEEFREKVMKKKEIIAIGGGKSKISFIFSMLGKAIKRSP---WTALLIALIISGVSLYG 415 F + K + G G I+ + + R+P +A++ L++ L G Sbjct: 347 GRSVFWPGGVDKAAERSRGAG------IWHRIAALVARAPVKVASAVIALLVVLSAGLLG 400 Query: 416 ASKITTEVRLEKMIPTDLPEIQALSDIRSEFGGQD---EVTILIKADDVRDPTLVRDILR 472 + + + T+ Q L IR EFG + ++ D++R DI Sbjct: 401 YQESFNTLSGFR-AATESEHGQHL--IREEFGPGEIAPSTVVVHSQDNLRSSPAPADIA- 456 Query: 473 FEREIKADSYINNVFETQSIADVVIQKYGYIPQDKEKISEAIEGSSLVSSDYSMTIIKLK 532 + + + +AD + K G K + I L YS + Sbjct: 457 --------TALTDADHVSRVADPRMGKDG-----KTVFYDVI----LDLDPYSSKALDAI 499 Query: 533 GNFMGVTQSEFNRIMEYFERAIQRADFPPGVKVELAGESYLNYVLNDLVNEELGKISTIG 592 G TQS A Q A V + GE+ N + ++ + I + Sbjct: 500 GPLKQATQS-----------AAQAAGVQDAT-VLIGGETAQNADIRSALDRDTTLIVLLV 547 Query: 593 TLIVVMVVFAIFR---RPTVSIAMIMPMFLGAL-----WTIGYMGLAGIPFSQTLAGVVS 644 IV +V+ + R P +A ++ FL L +T+ +G GI ++ A + Sbjct: 548 LAIVTVVLVLLLRSLLAPLYLVATLLLSFLATLGATTFFTVTVLGDDGIG-NRVTAYIFV 606 Query: 645 MIVGLGVDYGMHITHRFLEELNEGNKTPIIT-ALESVGPGIFVGALTTAGGFLALLSAQL 703 +V LGVDY + I RF +EL IT AL G I L A F L++ + Sbjct: 607 FLVALGVDYNIFIMSRFKQELRTQPPAKAITAALTRTGGVISSAGLILAATFAVLMTQPI 666 Query: 704 TAIHDFGRVLAVGIFASMFAAY-LVTPAILQL 734 + FG +A GI F L+ PAI++L Sbjct: 667 RELFQFGFAMACGILLDTFLIRPLLVPAIVRL 698 >pir||D72329 hypothetical protein - Thermotoga maritima (strain MSB8) >gi|4981348|gb|AAD35899.1|AE001749_2 (AE001749) hypothetical protein [Thermotoga maritima] Length = 674 Score = 102 bits (253), Expect = 1e-20 Identities = 85/356 (23%), Positives = 170/356 (46%), Gaps = 43/356 (12%) Query: 3 RKIARVIVIYRHSLAVVTMFLLILSAYGITQLRFETDLSKQLPEDLEAVKSYFTLQNEFG 62 RKIA +++ VV + + LS + + +++ +D+ D E K+Y + +F Sbjct: 353 RKIALIVL-------VVFLVMAALSPFLLKRVQVGSDMVSYFERDSELRKAYDLIVKKFN 405 Query: 63 GSGSALIYVKIKNNDNVVDIRDPKIIEAMYSLEQRLREKEYVTDTFSIADLMVQILGRLP 122 IY+ ++ N V D KI++ L +++ + EYV+ D+ V I+ L Sbjct: 406 TREP--IYLVLEKNVPFVGT-DSKILK---ELIEKIEKSEYVSSVVFPVDIPVPIMYTLS 459 Query: 123 KNMDEVKFVLNMLPPEARNGLISGDYSSTIIIVNLNRE--KNQKALVRVYNDIEREIERT 180 + +K + GD + +IVNL E ++ K +V + N++ E + Sbjct: 460 RTNPFLKTFV-------------GDRNRIRLIVNLTPEGYEHVKKVVDLINEVVSETGWS 506 Query: 181 NFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPLVPL 240 ++ G V++ D+ E + +++ ++ I++ ++ ++ P+ L ++P+ Sbjct: 507 HYVAG-SVLIWNDIN------ESIMRSQIQSIVLASILIFAMVFIIFRRPLTTLSVMIPI 559 Query: 241 IFGVVMTLGFMGLLGIPLDIATTTVGAMIIGMGIDYGVHVTNRYYEERGKGKSLEEAAEE 300 F V FM L GI LD++T+ +++G+ IDY +H+ + E R + L Sbjct: 560 AFTTVFNFLFMALFGISLDVSTSITSGILMGLVIDYSIHIASE--ERRLRDPYL------ 611 Query: 301 AIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVTPAL 356 + G ++L AL I+GF L S L K +S+ +++G+G+ A+ +IV P + Sbjct: 612 VVKNVGPSVLTNALGLISGFAVLLFSELALFKNISLLMMLGIGVGAIFTLIVQPMI 667 >gb|AAD44231.1|AF143772_37 (AF143772) TmtpB [Mycobacterium avium] Length = 963 Score = 101 bits (249), Expect = 3e-20 Identities = 94/375 (25%), Positives = 156/375 (41%), Gaps = 33/375 (8%) Query: 106 DTFSIADLMVQILGRLPKNMDEVKFVLNMLPPEARNGLISGDYSSTIIIVNLNREKNQKA 165 D + D ++++L K++ V+ P R S D + + VNLN A Sbjct: 96 DAHTYYDRLIRLLENDHKHVQHVQNFWG--DPLTRGAAQSQDGKAAYVQVNLNGNAGAAA 153 Query: 166 LVRVYNDIEREIERTNFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLY 225 I + ++ + P G++V +TG I + Q + S I++ + LL Sbjct: 154 GDESVAAIRKLVQEASPPPGLKVYVTGPAPIVADMNIAGQKTVMLVTLASLIVIFVTLLL 213 Query: 226 FYKSPIRMLVPLV------PLIFGVVMTLGFMGLLGIPLDIATTTVGAMIIGMGIDYGVH 279 Y+S I +++ L+ + G+V LG +G++G+ A + A +I G DYG+ Sbjct: 214 VYRSVITVILLLLIVGLELQIARGMVALLGHLGVVGLTT-FAVNLLVAAVIATGTDYGIF 272 Query: 280 VTNRYYEERGKGKSLEEAAEEAIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLV 339 RY E R G+S EEA K +L + LT L LS + LP + L + + Sbjct: 273 FVGRYQEARQAGESREEAFYTTFNGVAKVVLASGLTIAGAVLCLSFTRLPYFQPLGIPVA 332 Query: 340 MGLGLAALNAVIVTPALAILEEEF-----REKVMKKKEIIAIGGGKSKISFIFSMLGKAI 394 +G+ +A L A+ + PAL F R V ++ + +G AI Sbjct: 333 VGISIAVLVALTLGPALLAAGARFGLFEPRRAVSARR---------------WRRIGTAI 377 Query: 395 KRSPWTALLIALIISGVSLYGASKITTEVRLEKMIPTDLPEIQALSDIRSEFGGQ----D 450 R P L+ L +S V L +K IP +P + F GQ Sbjct: 378 VRWPAPILIATLAVSLVGLLALPNYRPSYDDQKFIPDSIPANVGFAAAARHFPGQRMQMP 437 Query: 451 EVTILIKADDVRDPT 465 E+ ++ D+R+PT Sbjct: 438 EILLVETDHDLRNPT 452 >sp|O53784|MML5_MYCTU PUTATIVE MEMBRANE PROTEIN MMPL5 >gi|7478343|pir||E70826 probable membrane protein - Mycobacterium tuberculosis (strain H37RV) >gi|2909649|emb|CAA17459.1| (AL021943) mmpL5 [Mycobacterium tuberculosis] Length = 964 Score = 101 bits (248), Expect = 4e-20 Identities = 90/386 (23%), Positives = 160/386 (41%), Gaps = 21/386 (5%) Query: 116 QILGRLPKNMDEVKFVLNML-PPEARNGLISGDYSSTIIIVNLNREKNQKALVRVYNDIE 174 Q++GRL + V+ + + P G S D + + V L + + ++ Sbjct: 111 QMIGRLQADTTHVQSLQDFWGDPLTATGAQSSDGKAAYVQVKLAGNQGESLANESVEAVK 170 Query: 175 REIERTNFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRML 234 +ER P GV+V +TG + + + A++ +++++LL Y+S I Sbjct: 171 TIVERLAPPPGVKVYVTGSAALVADQQQAGDRSLQVIEAVTFTVIIVMLLLVYRSIITSA 230 Query: 235 VPLVPLIFGVVMTLGFMGLLGIPLDI-----ATTTVGAMIIGMGIDYGVHVTNRYYEERG 289 + L ++ G++ T G + LG I AT + + I DY + + RY E RG Sbjct: 231 IMLTMVVLGLLATRGGVAFLGFHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRYQEARG 290 Query: 290 KGKSLEEAAEEAIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNA 349 G+ E A T +LG+ LT LS + LP + L V L +G+ + A Sbjct: 291 LGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQTLGVPLAIGMVIVVAAA 350 Query: 350 VIVTPALAILEEEFREKVMKKKEIIAIGGGKSKISFIFSMLGKAIKRSPWTALLIALIIS 409 + + PA+ + F K+++ K + + G + +G AI R P L+ A+ ++ Sbjct: 351 LTLGPAIIAVTSRF-GKLLEPKRMARVRGWRK--------VGAAIVRWPGPILVGAVALA 401 Query: 410 GVSLYGASKITTEVRLEKMIPTDLPEIQALSDIRSEFGG---QDEVTILIKADDVRDPTL 466 V L T +P DLP + + F EV ++ D+R+ Sbjct: 402 LVGLLTLPGYRTNYNDRNYLPADLPANEGYAAAERHFSQARMNPEVLMVESDHDMRNSA- 460 Query: 467 VRDILRFEREIKADSYINNVFETQSI 492 D L + KA + + Q+I Sbjct: 461 --DFLVINKIAKAIFAVEGISRVQAI 484 >emb|CAB90894.1| (AL355753) putative integral membrane protein. [Streptomyces coelicolor A3(2)] Length = 739 Score = 97.1 bits (238), Expect = 6e-19 Identities = 125/560 (22%), Positives = 229/560 (40%), Gaps = 69/560 (12%) Query: 205 QNDMNRTMAISGI-IVVLILLYFYKSPIRMLVPLVPLIFGVVMTLGFMGLLGIPLDI-AT 262 + +M T + GI + ++LL + S + +PL+ I GV + + +G LG L++ AT Sbjct: 171 EQEMGGTAELIGIGVAAIVLLLTFGSLVAAGMPLLSAIIGVGIGISAIGALGSTLELSAT 230 Query: 263 TTVGAMIIGMG--IDYGVHVTNRYYEERGKGKSLEEAAEEAIAETGKALLGAALTTIAGF 320 T+ AM+IG+ IDY + + +RY E +G++ EEAA A+ G A++ A LT + Sbjct: 231 TSTLAMMIGLAVAIDYALFIVSRYRAEISEGRAPEEAAGRAVGTAGSAVVFAGLTVVVAL 290 Query: 321 LALSISILPSLKRLSVSLVMGLGLAALNAVIVTPALAIL--EEEFREKVMKKKEIIAIGG 378 L+I +P L ++ ++ +G+A L A+ +TPAL + K K Sbjct: 291 AGLAIVNIPILTKMGLAAAGTVGIAVLIALTLTPALLGFAGKRALSRKDRKAPAGARAAS 350 Query: 379 GKSKISFIFSMLGKAIKRSPWTALLIALIISGVSLYGASKITTEVRLEKMIPTDLPEIQA 438 GK K+ + + ++R P T LL A++ GV A+ + + E D + +A Sbjct: 351 GKPKLG---TRWARFVQRRPVTVLLTAVLGLGVIAVPAAGMELGLPDEGSSAPDTTQRKA 407 Query: 439 LSDIRSEFGG--QDEVTILIKADDVRDPTLVRDILRFEREIKADSYINNVFETQSIADVV 496 + FG + + + A DP D + I + E ++ Sbjct: 408 YDMLSESFGAGFNGPLMVTVDARGADDPKAAADTV--------GEKITGLGEAAAVTPAN 459 Query: 497 IQKYGYIPQDKEKISEAIEGSSLVSSDYSMTIIKLKGNFMGVTQSEFNRIMEYFERAIQR 556 + EG + V +T++ G T+S + I R Sbjct: 460 FNE---------------EGDTAV-----LTVMPKTGPSDVATESLVHDIRSL--SGDIR 497 Query: 557 ADFPPGVKVELAGESYLNY--VLNDLVNEELGKISTIGTLIVVMVVFAIF--RRPTVSIA 612 AD + V A +++ L+D + L + + L++++V ++ + + Sbjct: 498 ADTGAAMLVTGATAMTIDFSQTLDDALIPYLALVVGLAFLLLMLVFRSVLVPLKAALGFL 557 Query: 613 MIMPMFLGALWTIGYMGLAGIPFSQTLAG---------VVSMIVGLGVDYGMHITHRFLE 663 + + LGA+ + G F G ++ ++ GL +DY + + R E Sbjct: 558 LSVAAALGAVVAVFQWGWLADVFGVDQPGPIMSMMPIFMIGVVFGLAMDYEVFLVTRMRE 617 Query: 664 ELNEGNKTPIITALESVGPGIFVGALTTAGGFLALLSA---------QLTAIHDFGRVLA 714 G +A ESV G G A + ++S + + FG +A Sbjct: 618 AYVHGE-----SAAESVTTGFTHGGRVVAAAAIIMISVFSGFILENDAMIKMMGFGLAIA 672 Query: 715 VGIFASMFAAYLVTPAILQL 734 V +F + + PA+L L Sbjct: 673 V-LFDAFVVRMAIVPAVLAL 691 >pir||B81282 probable integral membrane protein Cj1373 [imported] - Campylobacter jejuni (strain NCTC 11168) >gi|6968807|emb|CAB73800.1| (AL139078) putative integral membrane protein [Campylobacter jejuni] Length = 823 Score = 94.4 bits (231), Expect = 4e-18 Identities = 151/832 (18%), Positives = 335/832 (40%), Gaps = 116/832 (13%) Query: 1 MLRKIARVIVIYRHSLAVVTMFLLILSAYGITQLRFETDLSKQLPEDLEAVKSYFTLQNE 60 M K+ + + S T+F+ + ++ +L + L ED +K++ + Sbjct: 1 MFAKLLKFFISRPKSTFFGTLFICLFLSFFAFKLSVDASAESLLLEDDADLKTFREISKH 60 Query: 61 FGGSGSALIYVKIKN-----NDNVV-------DIRDPKIIEAMYSL-EQRLREKEYVTDT 107 + L+ K + N+N+ ++ ++E ++S+ L + TD Sbjct: 61 YKSDNFLLLAFKPYDEKPFSNENLAKLKKLHEELEKAPLVERVFSIINAPLLQSSQNTD- 119 Query: 108 FSIADLMVQILGRLPKNMDEVKFVLNML-PPEARNGLISGDYSSTIIIVNLN-------- 158 + +L+ I ++++ K +L P +N +IS D T +I+ L Sbjct: 120 --LKELLKNIPNIESQDINRTKAQNEILNSPFYKNNIISKDGKVTGLIIYLKPDTVYNNL 177 Query: 159 ----------REKNQKAL-VRVYNDIEREIERT----------NFPQGVEVVLTGDLG-I 196 +EK+Q L ++ + D ++ I + N+ + + + G + I Sbjct: 178 IEKRDLATDEKEKDQIRLAIKEHQDKQKVITKQSLDTIKSIVRNYEKNKDTLYLGGVSMI 237 Query: 197 TYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPLVPLIFGVVMTLGFMGLLGI 256 ++ +++D+ ++ L L YF++S + +PL + G LL Sbjct: 238 ADDMIAYIKSDLVLYGVSLVFLLGLALYYFFRSWRFVFLPLFICFISLSAASGVFALLNF 297 Query: 257 PLDIATTTVGAMIIGMGIDYGVHVTNRYYE--ERGKGKSLEEAAEEAIAETGKALLGAAL 314 + + ++ A+++ + + VH+ + E + +E E + L A + Sbjct: 298 QITVISSNYVALVLIITLSVVVHLITHFIESTQNHPKAKVERIVLETLLAKANPSLYAIV 357 Query: 315 TTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVTPALAIL-------EEEFREKV 367 TT+ GF +L +S + + +L + + +G+GLA + + + ++ +L ++EF+ + Sbjct: 358 TTMIGFFSLILSNIEPIIKLGIMMSIGIGLALIFSYLFLASILVLLKPKNYHKKEFKFNL 417 Query: 368 MKKKEIIAIGGGKSKISFIFSMLGKAIKRSPWTALLIALIISGVSLYGASKITTEVRLEK 427 + A+ K ++ + S+L A+++ALI G SK+ E Sbjct: 418 LAFCAKTALDPKKRRMIYEISVL----------AIILALI-------GISKLRVENSFVN 460 Query: 428 MIPTDLPEIQALSDIRSEFGGQDEVTILIKADDVRDPTLVRDIL-RFEREIKADSYINNV 486 + L I GG + ++I+ + ++ D L FE E + + Sbjct: 461 YFKDGSEIKKGLLVIDKNLGGTLPLEVIIRFPNNKNDQNASDTLDSFESEFE-NLATQET 519 Query: 487 FETQSIADVVIQKYGYIPQDKEKISEAIEGSSLVS-----------SDYSMTIIK----- 530 + S + +K ++KE + + +SL++ D+++ + Sbjct: 520 YWFDSKKTRIAKKVHEFLENKEFVGSVLSLNSLLTLGKNINDGKELDDFALAFLNENLPA 579 Query: 531 -----LKGNFMGVTQSEFNRIMEYFER--AIQRADF-------------PPGVKVELAGE 570 L F+ + +E M + ++R +F GV+V++ G Sbjct: 580 KFKQDLLSPFVSIENNELRFSMRIVDSDPNLRRNEFLIDLKKQLNELVKNDGVEVQITGI 639 Query: 571 SYL-NYVLNDLVNEELGKISTIGTLIVVMVVFAI-FRRPTVSIAMIMPMFLGALWTIGYM 628 L N +L L + + + I ++ + ++F I FR S+A I+ + M Sbjct: 640 MVLYNNMLQSLFSSQFDTL--IFVILAIFILFIIVFRDLKFSVAAILVNVIPLSVVFALM 697 Query: 629 GLAGIPFSQTLAGVVSMIVGLGVDYGMHITHRFLEEL-NEGNKTPIITALESVGPGIFVG 687 GL GIP + ++ +G+GVD +H +RF EE+ N+ + I+ + S+G ++ Sbjct: 698 GLLGIPLDMMSITIAAIAIGIGVDDAIHYIYRFREEIKNKSLEEAIMISHLSIGSALYYT 757 Query: 688 ALTTAGGFLALLSAQLTAIHDFGRVLAVGIFASMFAAYLVTPAILQLEFGRK 739 ++ GF ++S+ FG + + + + + P+ L + +K Sbjct: 758 TISIVLGFSVMMSSNFIPTIYFGILTVFVMILLLSGSLFLLPSFLITIYSKK 809 Score = 92.4 bits (226), Expect = 2e-17 Identities = 87/362 (24%), Positives = 160/362 (44%), Gaps = 58/362 (16%) Query: 13 RHSLAVVTMFLLILSAYGITQLRFETDLSKQLPEDLEAVKSYFTLQNEFGGSGSALIYVK 72 R + +++ +IL+ GI++LR E + E K + GG+ + ++ Sbjct: 431 RRMIYEISVLAIILALIGISKLRVENSFVNYFKDGSEIKKGLLVIDKNLGGTLPLEVIIR 490 Query: 73 IKNNDNVVDIRDP---------------------KIIEAMYSLEQRLREKEYVTDTFSIA 111 NN N + D K + + L KE+V S+ Sbjct: 491 FPNNKNDQNASDTLDSFESEFENLATQETYWFDSKKTRIAKKVHEFLENKEFVGSVLSLN 550 Query: 112 DLMVQILGRLPKNMDEVK--------FVLNMLPPEARNGLISG---------DYSSTIII 154 L+ L KN+++ K F+ LP + + L+S +S I+ Sbjct: 551 SLLT-----LGKNINDGKELDDFALAFLNENLPAKFKQDLLSPFVSIENNELRFSMRIVD 605 Query: 155 VNLNREKNQKALVRVYNDIEREIERTNFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAI 214 + N +N+ + D+++++ GVEV +TG + + +L+ L + T+ Sbjct: 606 SDPNLRRNEFLI-----DLKKQLNELVKNDGVEVQITGIMVLYNNMLQSLFSSQFDTLIF 660 Query: 215 SGIIVVLILLYFYK----SPIRMLVPLVPLIFGVVMTLGFMGLLGIPLDIATTTVGAMII 270 + + ++ + ++ S +LV ++PL VV L MGLLGIPLD+ + T+ A+ I Sbjct: 661 VILAIFILFIIVFRDLKFSVAAILVNVIPL--SVVFAL--MGLLGIPLDMMSITIAAIAI 716 Query: 271 GMGIDYGVHVTNRYYEERGKGKSLEEAAEEAIAETGKALLGAALTTIAGF-LALSISILP 329 G+G+D +H R+ EE K KSLEEA + G AL ++ + GF + +S + +P Sbjct: 717 GIGVDDAIHYIYRFREEI-KNKSLEEAIMISHLSIGSALYYTTISIVLGFSVMMSSNFIP 775 Query: 330 SL 331 ++ Sbjct: 776 TI 777 >emb|CAB89762.1| (AL354616) putative integral membrane protein. [Streptomyces coelicolor A3(2)] Length = 748 Score = 94.0 bits (230), Expect = 5e-18 Identities = 116/549 (21%), Positives = 219/549 (39%), Gaps = 57/549 (10%) Query: 213 AISGIIVVLILLYFYKSPIRMLVPLVPLIFGVVMTLGFMGLLG--IPLDIATTTVGAMI- 269 AI + ++LL + S +PL+ + GV +++ + LG + L + T T+ +M+ Sbjct: 181 AIGIALAAVVLLITFGSLAAAGLPLLTAVIGVGVSMCAILALGSTLGLTMTTGTLASMLG 240 Query: 270 IGMGIDYGVHVTNRYYEERGKGKSLEEAAEEAIAETGKALLGAALTTIAGFLALSISILP 329 + +GIDY + V +RY EER G + EAA A+ G A++ A LT I + L++ +P Sbjct: 241 LAVGIDYALFVVSRYREERANGHAPREAAGLAVGTAGSAVVFAGLTVIIALVGLTVIGVP 300 Query: 330 SLKRLSVSLVMGLGLAALNAVIVTPALAIL--EEEFREKVMKKKEIIAIGGGKSKISFIF 387 L ++ + + +A L A+ + PAL + +V K +E G S Sbjct: 301 MLTKMGLCAAGAVAIAVLVALTLVPALLGMWPNAVLSRRVRKFREADKRDGNAKHHSETP 360 Query: 388 SMLG----KAIKRSPWTALLIALIISGVSLYGASKITTEVRLEKMIPTDLPEIQALSDIR 443 G + + R P LL+ + + GV A+ + + ++ PT E +A + Sbjct: 361 DNGGTRWARFVMRRPVAVLLLGVAVLGVLALPATHLEMGMPGDEAKPTSTTERRAYDALA 420 Query: 444 SEFGGQDEVTILIKADDVRDPTLVRDILRFEREIKADSYINNVFETQSIADVVIQKYGYI 503 FG + + A DV+D T + + A + + +T + V Sbjct: 421 DGFGAGFNGPLTVVA-DVKDAT--------DPQAAAATMAEQIKDTDGVVSVT------P 465 Query: 504 PQDKEKISEAIEGSSLVSSDYSMTIIKLKGNFMGVTQSEFNRIMEYFERAIQRADFPPGV 563 PQ E G + + S T G I++ + G Sbjct: 466 PQFNE------AGDTALFSAVPAT---------GPNTEATKEIVQTIRAERPGLEADTGA 510 Query: 564 KVELAGESYLNYVLNDLVNEELGKISTIGTLIVVMVVFAIFRRPTVSIAMIMPMFLGALW 623 E+ G + +N + + + L + L+ ++++ +FR V + + L L Sbjct: 511 TFEVTGSTAMNIDVAQALQDALVPYLAVIVLLSLLLLLIVFRSILVPVKAALGFLLSVLA 570 Query: 624 TIGYM----------GLAGIPFSQTLAG-----VVSMIVGLGVDYGMHITHRFLEELNEG 668 ++G + GL G+ + + +V ++ GL +DY + + R E G Sbjct: 571 SLGTVVAVFQWGWGAGLLGVEQTGPIMSLMPIFLVGIVFGLAMDYEVFLVARMREAYVHG 630 Query: 669 NK--TPIITALESVGPGIFVGALTTAGGFLALLSAQLTAIHDFGRVLAVGIFASMFAAYL 726 + ++T + A+ F + + + I G LAV + F + Sbjct: 631 ERPGQAVVTGFRHSARVVAAAAVIMMAVFSGFIGSGESMIKTIGFGLAVAVLFDAFVVRM 690 Query: 727 -VTPAILQL 734 + PA+L L Sbjct: 691 ALVPAVLAL 699 >emb|CAB89749.1| (AL354616) putative membrane protein [Streptomyces coelicolor A3(2)] Length = 716 Score = 92.1 bits (225), Expect = 2e-17 Identities = 125/578 (21%), Positives = 236/578 (40%), Gaps = 73/578 (12%) Query: 183 PQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPLVPLIF 242 P G+E+ +TG I + + + + + +V L+L+ Y+SP+ ++PLV + Sbjct: 162 PSGLELEVTGPGAIDGDMDAVFDGIDEQVLLTTIAVVTLLLILTYRSPVLWIIPLVAVGA 221 Query: 243 GVVMTLGFMGLL----GIPL-DIATTTVGAMIIGMGIDYGVHVTNRYYEERGKGKSLEEA 297 + ++G + LL GI + D + + ++ G+G DY + + RY E +++ A Sbjct: 222 AALTSMGTVYLLVKGFGIVVNDQNSALLTILVFGVGTDYALLLIARYREALHHQENVRGA 281 Query: 298 AEEAIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVTPALA 357 A+ A++ +A T ++G L L ++ L S L G+ A + + + PA+ Sbjct: 282 MVHALRGAAPAIVASAATVVSGLLCLLVADLNSTSGLGPIGAAGILCALVAMLTLFPAVL 341 Query: 358 IL--EEEFREKVMKKKEIIAIGGGKSKISFIFSMLGKAIKRSPWTALLIALIISGVSLYG 415 ++ F V + + G ++ LG AI R W A L + + GV G Sbjct: 342 VVLGRRIFWPAVPRFSTAVEEKPG------LWGRLGTAINRRRWVATLGSFGVLGVLALG 395 Query: 416 ASKITTEVRLEKM---IPTDLPEIQALSDIRSEFGGQDEVTILIKADDVRDPTLVRDILR 472 + TT +R + +P + L + E GGQ P V Sbjct: 396 LAGNTTALREQDQFLSVPESVTGFTVLREHFPELGGQ--------------PLTV----- 436 Query: 473 FEREIKADSYINNVFETQSIADVVIQKYGYIPQDKEKISEAIEGSSLVSSDYSMTIIKLK 532 F R + + ++ V +T+ +A V + E + G + +S + Sbjct: 437 FTRPAQQEKVLDVVEDTRGVALAVPE-------------ETVGGWANIS---------VF 474 Query: 533 GNFMGVTQSEFNRIMEYFERAIQRADFPPGVKVELAGESYLNYVLNDLVNEELGKISTIG 592 T +E++ I +R G + + G S N + ++ K+ Sbjct: 475 PKDAPDTAAEYDTI----KRVRTAVHMVSGAEAIVGGPSAEN-LDTEVTTRRDEKLVIPL 529 Query: 593 TLIVVMVVFAIFRR----PTVSIAMIMPMFLGALWTIGY-----MGLAGIPFSQTLAGVV 643 L+VV+++ + R P V +A ++ F A + +G G+ +S L + Sbjct: 530 VLVVVLIILGLLLRAVLAPLVLMATVVVSFAAAFGGSVFVFDTILGFKGVDYSVPLLAFL 589 Query: 644 SMIVGLGVDYGMHITHRFLEE-LNEGNKTPIITALESVGPGIFVGALTTAGGFLALLSAQ 702 +V LGVDY + + R +E + G + ++ AL + G I L A F L++ Sbjct: 590 -FLVALGVDYNIFLASRARQETMRLGAREGMLKALSATGGVITSAGLVLAATFGVLVTLP 648 Query: 703 LTAIHDFGRVLAVGIFASMFAAYLVTPAILQLEFGRKI 740 L + + G ++A G+ V L L GR++ Sbjct: 649 LVMLVEVGFLVAFGVLLDALLVRSVLVPALTLLIGRRM 686 >dbj|BAB04439.1| (AP001509) unknown conserved protein in others [Bacillus halodurans] Length = 687 Score = 89.3 bits (218), Expect = 1e-16 Identities = 153/749 (20%), Positives = 304/749 (40%), Gaps = 89/749 (11%) Query: 5 IARVIVIYRHSLAVVTMFLLILSAYGITQLRFETDLSKQLPEDLEAVKSYFTLQNEFGGS 64 IA I+ R ++ + L +SA + + +++ LP++ ++ K+ L+ EF + Sbjct: 4 IAAFIIKKRKTIVLSFAILTFISAIALFFVSVNYNMTDYLPDEAQSTKAIEVLEEEFDRT 63 Query: 65 GSALIYVKIKNNDNVVDIRDPKIIEAMYSLEQRLREKEYVTDTFSIADLMVQILGRLPKN 124 S N V+ IRD + EA+ ++ L E + V+D + +++ Sbjct: 64 VS---------NARVM-IRDVTVQEALL-YKKELEEIDGVSDVIWLDEVI---------- 102 Query: 125 MDEVKFVLNMLPPEARNGLISGDYSSTIIIVNLN-REKNQKALVRVYNDIEREIERTNFP 183 +++ L M A L+ Y + +L RE ++ A+ ++ Sbjct: 103 --DLETPLEM----ADKDLVKSYYKDESALFSLTIREGDEVAVTDAIYELI--------- 147 Query: 184 QGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPLVPLIFG 243 G + L+G+ T +M + ++ I+V+IL+ S I L L + Sbjct: 148 -GEDNALSGEAVNTAVSQQMTGKETIYAASLLIPIIVIILIISTTSWIEPLFFLTAIGVS 206 Query: 244 VVMTLGFMGLLGIPLDIATTTVGAMIIGMGIDYGVHVTNRYYEERGKGKSLEEAAEEAIA 303 V++ LG +G + + + + + +DY + + +R+ + R + + EEA + A+ Sbjct: 207 VLINLGTNIFIGEVSFVTQSVSPILQLAVSLDYAIFLLHRFSDYRKQTEDPEEAMQIAVR 266 Query: 304 ETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVTPALAILEEEF 363 ++ A+ +A TT GF AL+ L ++LV G+ L+ ++ ++ PAL I ++ Sbjct: 267 KSFPAIAASAATTFFGFTALTFMQFEIGADLGLNLVKGIVLSFISVMVFLPALTICFYKW 326 Query: 364 REKVMKK---KEIIAIGGGKSKISFIFSMLGKAIKRSPWTALLIALIISGVSLYGASKIT 420 +K + +IG G KI FI + +++L+I V Y A T Sbjct: 327 IDKTQHRPFFPRFQSIGNGVMKIRFI-------------SLAVVSLLI--VPSYLAQGQT 371 Query: 421 TEVRLEKMIPTDLPEIQALSDIRSEFGGQDEVTILIKADDVRDPTLVRDILRFEREIKAD 480 + + +P + I FG + +L+ DV R++ E+E++ Sbjct: 372 SFIYGIGELPESSRAGSDTATIEEVFGKSTPIVLLVPKGDV-----AREV-EMEQELEKV 425 Query: 481 SYINNVFE-TQSIADVVIQKYGYIPQDKEKISEAIEGSSLVSSDYSMTIIKLKGNFMGVT 539 YI NV QS++ + +Y I E++ S YS I+ + T Sbjct: 426 DYITNVISYNQSVSATIPSEY---------IDESVT-EQFYSEHYSQIILYTE------T 469 Query: 540 QSEFNRIMEYFERAIQRADFPPGVKVELAGESYLNYVLNDLVNEELGKISTIGTLIVVMV 599 E E + A G GES Y + + ++ ++ + + + +V Sbjct: 470 DVEGEVAFSVVETVQEIAASYYGDDALSLGESVSLYDMKTTIMKDNRVVNLLTVVAIAIV 529 Query: 600 VFAIFRRPTVSIAMIMPMFLGALW---TIGYMGLAGIPF-SQTLAGVVSMIVGLGVDYGM 655 + FR ++ + +++ + A+W + Y A + + + G V + VDY + Sbjct: 530 LLLTFRSISIPVILLLTI-QSAVWLNLAVPYFTDAPLVYLGYLIVGTVQL--AATVDYAI 586 Query: 656 HITHRFLEELNEGNKTPII--TALESVGPGIFVGALTTAGGFLALLSAQLTAIHDFGRVL 713 T +L + + I T E A+ ++ GF+ L++ + G +L Sbjct: 587 LYTEGYLVNRRKMPRRQAITKTLTEKTFSISISAAILSSVGFILWLTSSNPVVSSIGLLL 646 Query: 714 AVGIFASMFAAYLVTPAILQLEFGRKISK 742 G + PA+L L F + I K Sbjct: 647 GRGALLAFILVIFFLPAML-LVFDKAIRK 674 >emb|CAB59662.1| (AL132674) putative membrane transport protein [Streptomyces coelicolor A3(2)] Length = 745 Score = 87.4 bits (213), Expect = 5e-16 Identities = 149/772 (19%), Positives = 290/772 (37%), Gaps = 106/772 (13%) Query: 2 LRKIARVIVIYRHSLAVVTMFLLILSAYGITQLRFETDLSKQLPEDLEAVKSYFTLQNEF 61 L K+ R+ RH +A++ + LL L+ G + S +P EA K++ L+ F Sbjct: 5 LYKLGRLAFRRRHFVALIWVALLTLAGVGAASAPPAGNSSFSIP-GTEAQKAFDLLEQRF 63 Query: 62 GGSGS----ALIYVKIKNNDNVVDIRDPKIIEAMYSLEQRLREKEYVTDTFSIADLMVQI 117 G+ + A + K + + D + +E + + E ++ S+AD Sbjct: 64 PGASADGATARVVFKAPAGETMTDAGNKATVE------KTVDELADGSEVASVAD----- 112 Query: 118 LGRLPKNMDEVKFVLNMLPPEARNGLISGDYSSTIIIVNLNREKNQKALVRVYNDIEREI 177 P N +S D TI ++ + + L D + Sbjct: 113 -------------------PYTGNA-VSED--GTIAYASVKYDVSGMELEESTKDALEDA 150 Query: 178 ERTNFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPL 237 + G+ V + GD L+ + + T I + ++L+ + S + +PL Sbjct: 151 AQQARDAGLTVEIGGDA------LQAVP-ETGATEVIGIAVAAVVLVITFGSLVSAGLPL 203 Query: 238 VPLIFGVVMTLGFMGLLGIPLDI-ATTTVGAMIIGM--GIDYGVHVTNRYYEERGKGKSL 294 + + GV + + + L L++ +TT++ AM+IG+ GIDY + + +RY E +G+ Sbjct: 204 LTALIGVGIGVSSITALASALELGSTTSILAMMIGLAVGIDYALFIVSRYRAELAEGRER 263 Query: 295 EEAAEEAIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVTP 354 EEAA A+ G A++ A LT + + L++ +P L ++ ++ + +A L A+ + P Sbjct: 264 EEAAGRAVGTAGSAVVFAGLTVVIALVGLAVVNIPMLTKMGIAAAGTVAIAVLIALTMIP 323 Query: 355 A-LAILEEEFREKVMKKKEIIAIGGGKSK--------ISFIFSMLGKAIKRSPWTALLIA 405 A L + K K + G+ K + + + + R P LL+ Sbjct: 324 ALLGYAGRRVKPAGAKGKRLGRSRKGEPKPDRPAGQPKANLGTRWASFVVRRPLAVLLLG 383 Query: 406 LIISGVSLYGASKITTEVRLEKMIPTDLPEIQALSDIRSEFGGQDEVTILIKADDVRDPT 465 +I G + A+ + + + PT + +A + FG +++ D Sbjct: 384 VIGLGAAAVPAASLELGLPDDGSQPTSTTQRRAYDLLSEGFGPGFNGPLMVVVDAKGSDA 443 Query: 466 LVRDILRFEREIKADSYINNVFETQSIADVVIQKYGYIPQDKEKISEAIEGSSLVSSDYS 525 E+ IK + V +P K SS+ + D Sbjct: 444 PKDAFTDVEQRIKGLDGVVAVAPPAPNKGGDTATITVVPDSKP--------SSVQTEDLV 495 Query: 526 MTIIKLKGNFMGVTQSEFNRIMEYFERAIQRADFPPGVKVELAGESYLNYVLNDLVNEEL 585 I G+ T G + + G + +N ++ +N+ L Sbjct: 496 HAIRDAGGDVEAKT----------------------GAETLVTGATAMNIDVSQKLNDAL 533 Query: 586 GKISTIGTLIVVMVVFAIFRRPTVSIAMIMPMFLGAL-------------WTIGYMGL-- 630 + + +++ +FR V + + L + W G MG+ Sbjct: 534 VPYLVLVVGLAFLLLIVVFRSILVPLKAALGFLLSVMAALGAVVAVFQWGWLSGLMGVEE 593 Query: 631 AGIPFSQTLAGVVSMIVGLGVDYGMHITHRFLEELNEGNK--TPIITALESVGPGIFVGA 688 G S +V ++ GL +DY + + R E G K ++T + + A Sbjct: 594 TGPVMSMMPIFMVGVVFGLAMDYEVFLVTRMREAYVHGEKPNQAVVTGFKHGARVVTAAA 653 Query: 689 LTTAGGFLALLSAQLTAIHDFGRVLAVGIFASMFAAYL-VTPAILQLEFGRK 739 + F + + + + G LA+ +F F + + PA+L L G+K Sbjct: 654 VIMMAVFAGFIGSSESMVKMIGFGLAIAVFFDAFVVRMAIVPAVLAL-LGKK 704 >sp|P54881|MML4_MYCLE PUTATIVE MEMBRANE PROTEIN MMPL4 >gi|699243|gb|AAA63006.1| (U15183) transport protein [Mycobacterium leprae] Length = 959 Score = 87.4 bits (213), Expect = 5e-16 Identities = 77/337 (22%), Positives = 141/337 (40%), Gaps = 20/337 (5%) Query: 137 PEARNGLISGDYSSTIIIVNLNREKNQKALVRVYNDIEREIERTNFPQGVEVVLTGDLGI 196 P G S D + + ++L + + + + + + +T P G+ +TG + Sbjct: 126 PLTAPGAQSNDGKAAYVQLSLAGNQGELLAQESIDAVRKIVVQTPAPPGITAWVTGASAL 185 Query: 197 TYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPLVPLIF------GVVMTLGF 250 + M R A S I++++ LL Y+S I +++ L + GVV LG Sbjct: 186 IADMHHSGDKSMIRITATSVIVILVTLLLVYRSFITVILLLFTVGIESAVARGVVALLGH 245 Query: 251 MGLLGIPLDIATTTVGAMIIGMGIDYGVHVTNRYYEERGKGKSLEEAAEEAIAETGKALL 310 GL+G+ A + ++ I G DYG+ +T RY E R ++ E A T +L Sbjct: 246 TGLIGLST-FAVNLLTSLAIAAGTDYGIFITGRYQEARQANENKEAAFYTMYRGTFHVIL 304 Query: 311 GAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVTPALAILEEEFREKVMKK 370 G+ LT LS + +P + L V +G+ +A A+ + PA+ + F + + Sbjct: 305 GSGLTISGATFCLSFARMPYFQTLGVPCAVGMLIAVAVALTLGPAVLTVGSRF--GLFEP 362 Query: 371 KEIIAIGGGKSKISFIFSMLGKAIKRSPWTALLIALIISGVSLYGASKITTEVRLEKMIP 430 K +I + G + +G + R P L+ I+ V L T + +P Sbjct: 363 KRLIKVRG--------WRRIGTVVVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLP 414 Query: 431 TDLPEIQALSDIRSEFGG---QDEVTILIKADDVRDP 464 +P Q + F + E+ ++ D+R+P Sbjct: 415 ASIPANQGFAAADRHFPQARMKPEILMIESDHDMRNP 451 >sp|O50439|MMLA_MYCTU PUTATIVE MEMBRANE PROTEIN MMPL10 >gi|7479028|pir||G70876 probable transmembrane protein - Mycobacterium tuberculosis (strain H37RV) >gi|2695967|emb|CAA15860.1| (AL010186) mmpL10 [Mycobacterium tuberculosis] Length = 1002 Score = 86.2 bits (210), Expect = 1e-15 Identities = 89/372 (23%), Positives = 159/372 (41%), Gaps = 23/372 (6%) Query: 117 ILGRLPKNMDEVKFVLNMLP-PEARNGLISGDYSSTIIIVNLNREKNQKALVRVYNDIER 175 ++ RL + +V + + L P R L S D + I+ + L + Y D+ER Sbjct: 78 LVDRLRNDAKDVVMLQDFLTTPPLREVLGSKDGKAWILPIGLAGDLGTPKSYHAYTDVER 137 Query: 176 EIERTNFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLV 235 ++RT + +TG + + D +++++IL+ Y++P+ ML+ Sbjct: 138 IVKRTVAGTTLTANVTGPAATVADLTDAGARDRASIELAIAVMLLVILMVIYRNPVTMLL 197 Query: 236 PLVPL------IFGVVMTLGFMGLLGIPLDIATTTVGAMIIGMGIDYGVHVTNRYYEERG 289 PLV + +V + +G L + + A + AMI G G DY V + +RY+E Sbjct: 198 PLVTIGASLMTAQALVAGVSLVGGLAVS-NQAIVLLSAMIAGAGTDYAVFLISRYHEYVR 256 Query: 290 KGKSLEEAAEEAIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNA 349 G+ E A + A+ GK + +A T FL + + L + +L +G+ ++ L A Sbjct: 257 LGEHPERAVQRAMMSVGKVIAASAATVGITFLGMRFAKLGVFSTVGPALAIGIAVSFLAA 316 Query: 350 VIVTPALAILEEEFREKVMKKKEIIAIGGGKSKISFIFSMLGKAIKRSPWTALLIALIIS 409 V + PA+ +L R V + E +++ + G I R P A L A +I Sbjct: 317 VTLLPAILVLASP-RGWVAPRGE---------RMATFWRRAGTRIVRRP-KAYLGASLIG 365 Query: 410 GVSLYG-ASKITTEVRLEKMIPTDLPEIQALSDIRSEFGGQD---EVTILIKADDVRDPT 465 V+L AS K +P P + + F E I+ A D+R P Sbjct: 366 LVALASCASLAHFNYDDRKQLPPSDPSSVGYAAMEHHFSVNQTIPEYLIIHSAHDLRTPR 425 Query: 466 LVRDILRFEREI 477 + D+ + + + Sbjct: 426 GLADLEQLAQRV 437 >sp|Q11171|MML2_MYCTU PUTATIVE MEMBRANE PROTEIN MMPL2 >gi|7478399|pir||F70746 probable mmpL2 protein - Mycobacterium tuberculosis (strain H37RV) >gi|1449306|emb|CAB00933.1| (Z77162) mmpL2 [Mycobacterium tuberculosis] Length = 968 Score = 85.0 bits (207), Expect = 3e-15 Identities = 84/367 (22%), Positives = 150/367 (39%), Gaps = 28/367 (7%) Query: 137 PEARNGLISGDYSSTIIIVNLNREKNQKALVRVYNDIEREIERTNFPQGVEVVLTGDLGI 196 P G S D + ++V L +A V+ + ++ T P GV+ +TG + Sbjct: 124 PLTAAGSQSADDRAAYVVVYLVGNNETEAYDSVHA-VRHMVDTTPPPHGVKAYVTGPAAL 182 Query: 197 TYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPLVPLIFGVVMTLGFMGLLGI 256 E + + AI+ +++ +LL Y+S I ++ L+ + + GF+ LL Sbjct: 183 NADQAEAGDKSIAKVTAITSMVIAAMLLVIYRSVITAVLVLIMVGIDLGAIRGFIALLAD 242 Query: 257 P-----LDIATTTVGAMIIGMGIDYGVHVTNRYYEERGKGKSLEEAAEEAIAETGKALLG 311 AT + M I DY + + RY+E R G+ E A T +LG Sbjct: 243 HNIFSLSTFATNLLVLMAIAASTDYAIFMLGRYHESRYAGEDRETAFYTMFHGTAHVILG 302 Query: 312 AALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVTPALAILEEEFREKVMKKK 371 + LT LS + LP + L + +G+ +A L A+ + PA+ + F+ K++ Sbjct: 303 SGLTIAGAMYCLSFARLPYFETLGAPIAIGMLVAVLAALTLGPAVLTVGSFFKLFDPKRR 362 Query: 372 EIIAIGGGKSKISFIFSMLGKAIKRSPWTALLIALIISGVSLYGASKITTEVRLEKMIPT 431 + + +G AI R P L +++ + L T L K +P Sbjct: 363 ----------MNTRRWRRVGTAIVRWPGPVLAATCLVASIGLLALPSYRTTYDLRKFMPA 412 Query: 432 DLPEI--QALSDIRSEFGGQDEVTILIKAD-DVRDPTLVRDILRFEREIKADSYINNVFE 488 +P A + R + +LI+ D D+R+P D+L ++ K N++ Sbjct: 413 SMPSNVGDAAAGRRFSRARLNPEVLLIETDHDMRNPV---DMLVLDKVAK------NIYH 463 Query: 489 TQSIADV 495 + I V Sbjct: 464 SPGIEQV 470 >sp|O53735|MML4_MYCTU PUTATIVE MEMBRANE PROTEIN MMPL4 >gi|7478403|pir||C70831 probable mmpL4 protein - Mycobacterium tuberculosis (strain H37RV) >gi|2909525|emb|CAA17407.1| (AL021932) mmpL4 [Mycobacterium tuberculosis] Length = 967 Score = 84.7 bits (206), Expect = 3e-15 Identities = 79/365 (21%), Positives = 147/365 (39%), Gaps = 23/365 (6%) Query: 137 PEARNGLISGDYSSTIIIVNLNREKNQKALVRVYNDIEREIERTNFPQGVEVVLTGDLGI 196 P G+ S D + + ++L + + +E T P G++ +TG + Sbjct: 129 PLTAAGVQSNDGKAAYVQLSLAGNQGTPLANESVEAVRSIVESTPAPPGIKAYVTGPSAL 188 Query: 197 TYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPLVPL------IFGVVMTLGF 250 + M R ++ ++ ++LL Y+S I +++ L+ + GVV LG Sbjct: 189 AADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITVVLLLITVGVELTAARGVVAVLGH 248 Query: 251 MGLLGIPLDIATTTVGAMIIGMGIDYGVHVTNRYYEERGKGKSLEEAAEEAIAETGKALL 310 G +G+ A + + ++ I G DYG+ + RY E R G+ E A T +L Sbjct: 249 SGAIGLTT-FAVSLLTSLAIAAGTDYGIFIIGRYQEARQAGEDKEAAYYTMYRGTAHVIL 307 Query: 311 GAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVTPALAILEEEFREKVMKK 370 G+ LT LS + +P + L + +G+ +A AV +T A+L R + Sbjct: 308 GSGLTIAGATFCLSFARMPYFQTLGIPCAVGMLVAV--AVALTLGPAVLHVGSRFGLFDP 365 Query: 371 KEIIAIGGGKSKISFIFSMLGKAIKRSPWTALLIALIISGVSLYGASKITTEVRLEKMIP 430 K ++ + G + +G + R P L+ I+ V L T +P Sbjct: 366 KRLLKVRG--------WRRVGTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLP 417 Query: 431 TDLPEIQALSDIRSEFGG---QDEVTILIKADDVRDPTLVRDILRFEREIKADSYINNVF 487 +P Q + F + E+ ++ D+R+P D L ++ K + + Sbjct: 418 DFIPANQGYAAADRHFSQARMKPEILMIESDHDMRNPA---DFLVLDKLAKGIFRVPGIS 474 Query: 488 ETQSI 492 Q+I Sbjct: 475 RVQAI 479 >sp|O07800|MML8_MYCTU PUTATIVE MEMBRANE PROTEIN MMPL8 >gi|7478406|pir||C70522 probable mmpL8 protein - Mycobacterium tuberculosis (strain H37RV) >gi|3261809|emb|CAB10022.1| (Z97188) mmpL8 [Mycobacterium tuberculosis] Length = 1089 Score = 82.7 bits (201), Expect = 1e-14 Identities = 87/366 (23%), Positives = 162/366 (43%), Gaps = 44/366 (12%) Query: 137 PEARNGLISGDYSSTIIIV----NLNREKNQKALVRVYNDIEREIERTNFPQGVEVVLTG 192 P R + S D + I+ V +L ++++A RV + +E ++ + LTG Sbjct: 144 PPLRELMTSKDNQAWILPVGLPGDLGSTQSKQAYARVADIVEHQVAGSTLTAN----LTG 199 Query: 193 DLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPLVPLIFGVVMTLGFMG 252 + Q D +R I++++ILL Y +PI M++PL+ + VV+ + Sbjct: 200 PAATVADLNLTGQRDRSRIEFAITILLLVILLIIYGNPITMVLPLITIGMSVVVAQRLVA 259 Query: 253 LLGIP-LDIATTTV---GAMIIGMGIDYGVHVTNRYYEERGKGKSLEEAAEEAIAETGKA 308 + G+ L IA ++ M++G G DY V + +RY++ +G ++A ++A+ GK Sbjct: 260 IAGLAGLGIANQSIIFMSGMMVGAGTDYAVFLISRYHDYLRQGADSDQAVKKALTSIGKV 319 Query: 309 LLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVTPALAILEEEFREKVM 368 + +A T FL + + L LK + L + + + AV + PAL +L R + Sbjct: 320 IAASAATVAITFLGMVFTQLGILKTVGPMLGISVAVVFFAAVTLLPALMVLTGR-RGWIA 378 Query: 369 KKKEIIAIGGGKSKISFIFSMLGKAIKRSPWTALLIALII-------SGVSLYGASKITT 421 ++++ + G I R P T LL + ++ +G++ Y T Sbjct: 379 PRRDL---------TRRFWRSSGVHIVRRPKTHLLASALVLVILAGCAGLARYNYDDRKT 429 Query: 422 ----------EVRLEKMIPTDL--PE---IQALSDIRSEFGGQDEVTILIKADDVRDPTL 466 L+K P++L PE IQ+ +D+R+ D ++ + V + Sbjct: 430 LPASVESSIGYAALDKHFPSNLIIPEYLFIQSSTDLRTPKALADLEQMVQRVSQVPGVAM 489 Query: 467 VRDILR 472 VR I R Sbjct: 490 VRGITR 495 >emb|CAB56653.1| (AL121596) putative membrane transport protein [Streptomyces coelicolor A3(2)] Length = 765 Score = 82.3 bits (200), Expect = 2e-14 Identities = 116/565 (20%), Positives = 222/565 (38%), Gaps = 80/565 (14%) Query: 218 IVVLILLYFYKSPIRMLVPLVPLIFGVVMTLGFMGLLGIPLDIATTTVG-AMIIGM--GI 274 + ++LL + S +PL+ + GV +TL + LG L ++T + AM+IG+ G+ Sbjct: 184 VAAVVLLITFGSLAAAGLPLITAVVGVALTLASIVALGSALGMSTASGDLAMMIGIAVGV 243 Query: 275 DYGVHVTNRYYEERGKGKSLEEAAEEAIAETGKALLGAALTTIAGFLALSISILPSLKRL 334 DY + V +RY EER +G EAA A+ G A++ A LT + LS+ +PSL ++ Sbjct: 244 DYALLVVSRYREERAEGHDAREAAGLAVGTAGSAVVFAGLTVVIALAGLSVIGVPSLTKM 303 Query: 335 SVSLVMGLGLAALNAVIVTPAL------AILEEEFRE-----------KVMKKKEIIAIG 377 ++ + +A L + + PAL A+L R+ K + Sbjct: 304 GLAAAGAVVIAVLITLTLVPALCGFWPDALLARRVRKGRSAPPARRFRKGRSTPPARRLR 363 Query: 378 GG-------KSKISFIFSM-LGKAIKRSPWTALLIALIISGVSLYGASKITTEVRLEKMI 429 GG +++ + +S+ + ++R P LL + ++ G A + + ++ Sbjct: 364 GGPGRGAARRTREAGAWSVRWARFVQRRPVPVLLGSAVLLGALAVPALDLRLGMPGDEAK 423 Query: 430 PTDLPEIQALSDIRSEFGG--QDEVTILIKADDVRDPTLVRDILRFEREIKADSYINNVF 487 PT E +A + FG +T+++ A DP Sbjct: 424 PTSTTERRAYDALADGFGPGFNGPLTVVVDARQADDPRSA-------------------- 463 Query: 488 ETQSIADVVIQKYGYIPQDKEKISEAIEGSSLVSSDYSMTIIKLKGNFMGVTQSEFNRIM 547 +++D + G + + + A + + + + + T ++ Sbjct: 464 -VAAVSDRLAATAGVVSVAPPRFNAAKDTAVIQAVPAT-----------APTSERTEELV 511 Query: 548 EYFERAIQRADFPPGVKVELAGESYLNYVLNDLVNEELGKISTIGTLIVVMVVFAIFRRP 607 + G E+ G + LN + + + L + + +++ +FR Sbjct: 512 HTIRDERHATESATGATFEVTGTTALNIDVARKMTDALIPYLLVVVGLAFLLLLVVFRSV 571 Query: 608 TVSIAMIMPMFL------GALWTI---GY-MGLAGI----PFSQTL-AGVVSMIVGLGVD 652 V + + L GAL TI G+ GL G+ P T+ +V ++ GL +D Sbjct: 572 LVPLKAALGFLLSVGASFGALVTIFQNGHGAGLLGVEETGPVMSTMPLMLVGIVFGLAMD 631 Query: 653 YGMHITHRFLEELNEGNK--TPIITALESVGPGIFVGALTTAGGFLALLSAQLTAIHDFG 710 Y + + R E + G + ++T G + A+ F ++ T + G Sbjct: 632 YQVFLVSRMREAVVHGERPAEAVVTGFRHSGRVVTAAAVIMTSVFAGFMTGGETLLKMVG 691 Query: 711 RVLAVGIFASMFAAYLV-TPAILQL 734 LAV + F + PA+L L Sbjct: 692 FGLAVAVLFDAFVVRMAFVPAVLVL 716 >gb|AAF97217.1|AF271635_1 (AF271635) putative transport membrane protein C [Mycobacterium smegmatis] Length = 994 Score = 81.5 bits (198), Expect = 3e-14 Identities = 80/325 (24%), Positives = 133/325 (40%), Gaps = 23/325 (7%) Query: 177 IERTNFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVP 236 + RT P+GV V +TG + + + + A++ +I+ +LL Y+S I +++ Sbjct: 174 VARTPAPEGVSVYVTGAAPLVSDMQHSGNRSILKITAVTVVIIFAMLLMVYRSVITVILL 233 Query: 237 LVPLIFGVVMTLGFMGLLGIP--LDIATTTVGAMI---IGMGIDYGVHVTNRYYEERGKG 291 L+ + F V G + LG ++T V ++ I G DYG+ RY E R G Sbjct: 234 LIMVGFEVAAARGIVAFLGANEVFVLSTFAVNMLVFLAIAAGTDYGIFFFGRYQEARAAG 293 Query: 292 KSLEEAAEEAIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVI 351 + E A ++ + LT L+ + LP + V +G+ A AV Sbjct: 294 EDRETAYYSMYRGVTPVVMASGLTIAGAIFCLTFTRLPYFHTMGVPCAIGMLAAVAVAVT 353 Query: 352 VTPALAILEEEFREKVMKKKEIIAIGGGKSKISFIFSMLGKAIKRSPWTALLIALIISGV 411 + PA L K+K + G +G AI R P L+ +L ++ V Sbjct: 354 LVPAGVALAGRIGWLEPKRKMRVRRWRG----------IGTAIVRWPAPILVASLAVALV 403 Query: 412 SLYGASKITTEVRLEKMIPTDLPEIQALSDIRSEFGGQDEVT---ILIKAD-DVRDPTLV 467 L T IP D+P + F Q +T +++++D D+R+PT Sbjct: 404 GLLALPGYETSYNDRDYIPADIPANAGFAAADRHF-SQARMTPDILMVESDHDMRNPT-- 460 Query: 468 RDILRFEREIKADSYINNVFETQSI 492 D L + KA + V Q I Sbjct: 461 -DFLVLNKIAKAIFKVRGVSRVQGI 484 >pir||E71280 probable antibiotic transport protein - syphilis spirochete >gi|3323098|gb|AAC65756.1| (AE001250) antibiotic transport protein, putative [Treponema pallidum] Length = 888 Score = 80.4 bits (195), Expect = 7e-14 Identities = 102/489 (20%), Positives = 202/489 (40%), Gaps = 50/489 (10%) Query: 16 LAVVTMFLLILSAYGITQLRFETDLSKQLPEDLEAVKSYFTLQNEFGGSGSALIYVKIKN 75 L V L + A + LR + + + +P++ + + + FG LI +K + Sbjct: 31 LVAVLSALTLFFAVQLRTLRLDNNNFRFIPKENSVRIADQRIDSTFGSQVPVLIGIKREY 90 Query: 76 NDNVVDIRDPKIIEAMYSLEQRLREKEYVTDTFSIADLMVQILGRLPKNMDEVKFVLNML 135 V DP + + SL +R+ V +++ L + LG N+ + V + Sbjct: 91 TSVV----DPVFLADVRSLIERISAVPLVRAESTLSLLSAEYLGLRAGNIISERVVPDEF 146 Query: 136 PPEARN----------------GLISGDYSSTIIIVNLNREKNQ----------KALVRV 169 A L+S D S I+V L+ + +A++R+ Sbjct: 147 SGSAEEVQGVYRKLRDWDFYECSLVSRDLRSMQIVVFLDTSNEESSSPEAMAACRAIIRI 206 Query: 170 YNDIEREIERTNFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKS 229 + +T F GV V ++G E +D+ + + +I+++ L ++ Sbjct: 207 LGAWKSRDAQT-FVTGVTVF--NEMGN-----EASTHDLTLLVPLVVLIIIVALFVSFRR 258 Query: 230 PIRMLVPLVPLIFGVVMTLGFMGLLGIPLDIATTTVGAMIIGMGIDYGVHVTNRYY---E 286 + +PL+ ++ V LG M L IPL I + + ++I +G YG+H+ + Y+ Sbjct: 259 LAGIFLPLLTVVISTVWALGAMALCAIPLSILSAILPVILIAVGSAYGIHIVSAYFYGAS 318 Query: 287 ERGKGKSLEEAAE--EAIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGL 344 R E A EA+ + + + +ALTT GF++ + + + V +G+ Sbjct: 319 SRICSTRQEHRARIVEAVDKIIQPVFLSALTTFVGFVSFCFTSVVPIFEFGVFASVGVAS 378 Query: 345 AALNAVIVTPALAILEEEFREKVMKKKEIIAIGGGKSKISFIFSMLGKAIKRSPWTALLI 404 A A+++ P+L I+ +V A G + + I T L + Sbjct: 379 AFAVALMLIPSLLIIRGP-ESRVCAH----APDAGHEHMDTAITGTLMVIAHHYRTVLFV 433 Query: 405 ALIISGVSLYGASKITTEVRLEKMIPTDLPEIQALSDIRSEFGGQDEVTILIKADDVRDP 464 A + SL G S++ + L + ++ +Q+ ++ FGG +T+L+ + RD Sbjct: 434 AFLAVVFSLVGMSRLVIDNVLTEYFEPEVTVVQSDRFMQQHFGGSRSLTVLV-STPARDG 492 Query: 465 TLVR-DILR 472 ++ R D+L+ Sbjct: 493 SVARPDVLK 501 Score = 77.3 bits (187), Expect = 6e-13 Identities = 87/377 (23%), Positives = 163/377 (43%), Gaps = 55/377 (14%) Query: 398 PWTALLIALIISGVSLYGASKITTEVRLE----KMIPTDLPEIQALSDIRSEFGGQDEVT 453 PW ++ ++S ++L+ A ++ T +RL+ + IP + A I S FG Q V Sbjct: 28 PW---VLVAVLSALTLFFAVQLRT-LRLDNNNFRFIPKENSVRIADQRIDSTFGSQVPVL 83 Query: 454 ILIKAD--DVRDPTLVRDILRFEREIKADSYINNVFETQSIADVVIQKY----------- 500 I IK + V DP + D+ I A + +S ++ +Y Sbjct: 84 IGIKREYTSVVDPVFLADVRSLIERISAVPLVR----AESTLSLLSAEYLGLRAGNIISE 139 Query: 501 GYIPQDKEKISEAIEG------------SSLVSSDY-SMTIIKLKGNFMGVTQSEFNRIM 547 +P + +E ++G SLVS D SM I+ T +E + Sbjct: 140 RVVPDEFSGSAEEVQGVYRKLRDWDFYECSLVSRDLRSMQIVVFLD-----TSNEESSSP 194 Query: 548 EYFE--RAIQR---ADFPPGVKVELAGESYLNYVLNDLVNEELGKISTIGTLIVVMVVFA 602 E RAI R A + + G + N + N+ +L + + LI+++ +F Sbjct: 195 EAMAACRAIIRILGAWKSRDAQTFVTGVTVFNEMGNEASTHDLTLLVPLVVLIIIVALFV 254 Query: 603 IFRRPTVSIAMIMPMFLGALWTIGYMGLAGIPFSQTLAGVVSMIVGLGVDYGMHITHRF- 661 FRR ++ + + +W +G M L IP S A + +++ +G YG+HI + Sbjct: 255 SFRRLAGIFLPLLTVVISTVWALGAMALCAIPLSILSAILPVILIAVGSAYGIHIVSAYF 314 Query: 662 ------LEELNEGNKTPIITALESVGPGIFVGALTTAGGFLALLSAQLTAIHDFGRVLAV 715 + + ++ I+ A++ + +F+ ALTT GF++ + I +FG +V Sbjct: 315 YGASSRICSTRQEHRARIVEAVDKIIQPVFLSALTTFVGFVSFCFTSVVPIFEFGVFASV 374 Query: 716 GIFASMFAAYLVTPAIL 732 G+ ++ A ++ P++L Sbjct: 375 GVASAFAVALMLIPSLL 391 Score = 76.9 bits (186), Expect = 8e-13 Identities = 67/256 (26%), Positives = 112/256 (43%), Gaps = 15/256 (5%) Query: 498 QKYGYIPQDKEKISEAIEGSSLVSSDYSMTIIK-------LKGNFMGVT--QSEFNRIME 548 +KYG + E++ E I G L+ S + ++ LK N T Q + ++E Sbjct: 637 KKYGV--KTSEELQEIISGYLLLLSGKGLGLVDRAVDPRALKMNIQLGTKGQQDSYGVIE 694 Query: 549 YFERAIQRADFPPGVKVELAGESYLNYVLNDLVNEELGKISTIGTLIVVMVVFAI-FRRP 607 ++ I R +FP V E G + LNDLV + IS + +L VV ++ A+ +R Sbjct: 695 AVKKFI-RENFPQDVHAEFGGSVLVEQSLNDLVVQSQ-LISLVFSLCVVFIIIAVHYRSL 752 Query: 608 TVSIAMIMPMFLGALWTIGYMGLAGIPFSQTLAGVVSMIVGLGVDYGMHITHRFLEELNE 667 I +P+ + L G MG GI + V G+GVDY +H + E Sbjct: 753 FAGIIGTLPLGVSVLVNFGVMGFFGIKLNICTTMVAGFSSGIGVDYTIHYLAAYRRAWKE 812 Query: 668 -GNKTPIITALESVGPGIFVGALTTAGGFLALLSAQLTAIHDFGRVLAVGIFASMFAAYL 726 G K + G I L+ GF L+ ++ + DFG ++ + + S A+ Sbjct: 813 CGGKDFLTQTFYGSGRAILFNVLSVGSGFAVLMLSKFNVLADFGLLMVLAMLTSSVASLT 872 Query: 727 VTPAILQLEFGRKISK 742 + P +L + R I++ Sbjct: 873 LLPTLLNVVKPRFITR 888 Score = 71.0 bits (171), Expect = 4e-11 Identities = 49/204 (24%), Positives = 94/204 (46%), Gaps = 3/204 (1%) Query: 155 VNLNREKNQKALVRVYNDIE--REIERTNFPQGVEVVLTGDLGITYKILEMLQNDMNRTM 212 + +N + K Y IE ++ R NFPQ V G + + + +++ ++ Sbjct: 675 LKMNIQLGTKGQQDSYGVIEAVKKFIRENFPQDVHAEFGGSVLVEQSLNDLVVQSQLISL 734 Query: 213 AISGIIVVLILLYFYKSPIRMLVPLVPLIFGVVMTLGFMGLLGIPLDIATTTVGAMIIGM 272 S +V +I+ Y+S ++ +PL V++ G MG GI L+I TT V G+ Sbjct: 735 VFSLCVVFIIIAVHYRSLFAGIIGTLPLGVSVLVNFGVMGFFGIKLNICTTMVAGFSSGI 794 Query: 273 GIDYGVHVTNRYYEERGKGKSLEEAAEEAIAETGKALLGAALTTIAGFLALSISILPSLK 332 G+DY +H Y K ++ + +G+A+L L+ +GF L +S L Sbjct: 795 GVDYTIHYL-AAYRRAWKECGGKDFLTQTFYGSGRAILFNVLSVGSGFAVLMLSKFNVLA 853 Query: 333 RLSVSLVMGLGLAALNAVIVTPAL 356 + +V+ + +++ ++ + P L Sbjct: 854 DFGLLMVLAMLTSSVASLTLLPTL 877 >sp|Q50585|MMLC_MYCTU PUTATIVE MEMBRANE PROTEIN MMPL12 >gi|7478398|pir||B70723 probable mmpL12 protein - Mycobacterium tuberculosis (strain H37RV) >gi|1477435|emb|CAB01394.1| (Z77826) mmpL12 [Mycobacterium tuberculosis] Length = 1146 Score = 79.2 bits (192), Expect = 2e-13 Identities = 77/352 (21%), Positives = 158/352 (44%), Gaps = 25/352 (7%) Query: 137 PEARNGLISGDYSSTIIIVNLNREKNQKALVRVYNDIEREIERTNFPQGVEVVLTGDLGI 196 PE + L S D + + + + + + +++T + V L+G + Sbjct: 126 PEMKELLASKDNKAWNLPITFAGDAASPETQAAFKRVAAIVKQTVAGTSLTVHLSGPIAT 185 Query: 197 TYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPLVPLIFGVVM---TLGFMGL 253 + E+ + D+ + + V++IL+ Y++ + MLVPL + VV TL + Sbjct: 186 VADLTELGEKDVRIIEIGTAVSVLIILILVYRNLVTMLVPLATIGASVVTAQGTLSGLAE 245 Query: 254 LGIPLDI-ATTTVGAMIIGMGIDYGVHVTNRYYEERGKGKSLEEAAEEAIAETGKALLGA 312 G+ +++ A + A++IG G DY V + +RY++ G+ + A ++A+ GK + + Sbjct: 246 FGLAVNMQAIVFMSAVMIGAGTDYAVFLISRYHDYVRHGEKSDMAVKKALMSIGKVITAS 305 Query: 313 ALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVTPALAILEEEFREKVMKKKE 372 A T FLA+ + L + ++ + + ++ L AV + PA+ L R + +++ Sbjct: 306 AATVAVTFLAMVFTKLEVFSAVGPAIAVAITVSLLGAVTLLPAILTLTGR-RGWIKPRRD 364 Query: 373 IIAIGGGKSKISFIFSMLGKAIKRSPWTALLIALIISGVSLYGASKITTEVRLE----KM 428 + + +S + + ++RS T L+ +I V+L G T +R K Sbjct: 365 LTSRMWRRSGV--------RIVRRS--TIHLVGSLIVLVALAGC---TLLIRFNYDDLKT 411 Query: 429 IPTDLPEIQALSDIRSEF--GGQDEVTILIKAD-DVRDPTLVRDILRFEREI 477 +P + ++ + F + + IK+ D+R P + DI REI Sbjct: 412 VPQHVESVKGYEAMNRHFPMNAMTPMVLFIKSPRDLRTPGALADIEMMSREI 463 >sp|Q49619|MMLA_MYCLE PUTATIVE MEMBRANE PROTEIN MMPL10 >gi|2145979|pir||S72698 transport protein tp1 - Mycobacterium leprae >gi|466786|gb|AAA17062.1| (U00010) transport protein (similarity to antibiotic transport protein actII-3 from S.coelicolor); tp1; Lepb1170_C1_181 [Mycobacterium leprae] Length = 1008 Score = 78.0 bits (189), Expect = 3e-13 Identities = 83/377 (22%), Positives = 157/377 (41%), Gaps = 26/377 (6%) Query: 117 ILGRLPKNMDEVKFVLNMLP-PEARNGLISGDYSSTIIIVNLNREKNQKALVRVYNDIER 175 ++ RL + +V + + L P L+S D + I+ + L E A + Y + Sbjct: 104 LVDRLRNDTKDVVVLQDFLSTPPLHELLVSKDGKAWILPIVLAGELGTSASYQAYAGVAG 163 Query: 176 EIERT---NFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIR 232 +++T ++ LTG + + D + ++++ IL+ Y++PI Sbjct: 164 IVKQTLESTAGSSLKANLTGPASTVADLTDAGARDRTSIELVIAVLLLTILMIIYRNPIT 223 Query: 233 MLVPLVPLIFGVVMTLGFMGLLGIPLDIATTT-----VGAMIIGMGIDYGVHVTNRY--Y 285 ML+PL+ + ++ + + + +A + + AMI G G DY V + +RY Y Sbjct: 224 MLLPLITIGASLMTAQAVVSGVSVLAGLAVSNQMIVLLSAMIAGAGTDYAVFLISRYHDY 283 Query: 286 EERGKGKSLEE--AAEEAIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLG 343 G G + + A +A+ GK + +A T FL +S + + + +L +G+ Sbjct: 284 IRMGSGSAQDAGCAVRQALISLGKVIAASAATVGITFLGMSFTKIRVFSTVGPALAIGIA 343 Query: 344 LAALNAVIVTPALAILEEEFREKVMKKKEIIAIGGGKSKISFIFSMLGKAIKRSPWTALL 403 +A L AV + PAL +L R V +++ + + G I R P L Sbjct: 344 VAFLAAVTLMPALLVLAGT-RGWVAPRRD---------RAGAFWRRTGVRIVRRPVAYLS 393 Query: 404 IALIISGVSLYGASKITTEVRLEKMIPTDLPEIQALSDIRSEFG-GQ--DEVTILIKADD 460 +++I V AS + K IP + + S F GQ E ++ D Sbjct: 394 ASMVILIVLALCASLVRFNYDDRKQIPASDESSVGYAALESHFPVGQAIPEYLLIQSPHD 453 Query: 461 VRDPTLVRDILRFEREI 477 +R P + D+ + + Sbjct: 454 LRTPRALADMAELAQRV 470 >pir||A75560 conserved hypothetical protein - Deinococcus radiodurans (strain R1) >gi|6457770|gb|AAF09696.1|AE001873_6 (AE001873) conserved hypothetical protein [Deinococcus radiodurans] Length = 749 Score = 76.5 bits (185), Expect = 1e-12 Identities = 125/650 (19%), Positives = 258/650 (39%), Gaps = 58/650 (8%) Query: 120 RLPKNMDEVKFVLNMLPPEARNGLISGDYSSTIIIVNLN---REKNQKALVRVYNDIERE 176 R + +VK V +LP + R GL S D + T+ + +E ++A+ R+ R Sbjct: 100 RFVSGLRDVKGVTRVLPAQ-RGGLGSRDAAGTLALTVAQIPLQEDGKEAVARI-----RA 153 Query: 177 IERTNFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVP 236 R +++ +TG I E+ + D R+ ++ ++ L+LL + + + +P Sbjct: 154 YVRRVASPALDIRVTGGQAIADDFTELAEADTKRSEFVALPLIALLLLLVFGALVATGLP 213 Query: 237 LVPLIFGVVMTLGFMGLLGIPLDIAT---TTVGAMIIGMGIDYGVHVTNRYYEERGKGKS 293 LV + + + + + L ++++T + V + +G GIDY + + NR+ EE + + Sbjct: 214 LVIGMLSISVAMAGLYFLTTVMEVSTFAQSVVTMLGLGAGIDYALLMVNRFREELARRGN 273 Query: 294 LEEAAEEAIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVT 353 EAA + G+++L + T L + L ++ + + V+ + L L ++ Sbjct: 274 AAEAAARTVETAGRSVLFSGSTVAIAMAGLLLPPLSFVRSIGIGGVLAVVLTVLASLTAL 333 Query: 354 PALAILEEEFREKVMKKKEIIAIGGGKSKISFIFSMLGKAIKRSPWTALLIALIISGVSL 413 PAL L ++V + + + + S ++ + + P ++++ + Sbjct: 334 PALLTL---LGDRVNAPRLLRSTWAQSAGASAAWTAFARRVTARPLAVVVLSTAFLLLLA 390 Query: 414 YGASKITTEVRLEKMIPTDLPEIQALSDIRSEFGG--QDEVTILIKADDVRDPTLVRDIL 471 AS++ T + + AL D+R G + +L+ + R Sbjct: 391 VPASRMKTGYAGAWGLVPGVESRDALQDVRDMGAGGLLSQYEVLLDLEGKRYTP------ 444 Query: 472 RFEREIKADSYINNVFETQSIADVVIQKYGYIPQDKEKISEAIEGSSLVSSDYSMTIIKL 531 ++ + + +N++ + V+ P D + S + Sbjct: 445 --DQSARFQAVVNDLRALPGVRAVL--SPFLTPADLQAAGGGTSDGLAALSLLTQRSFSR 500 Query: 532 KGNFMGVTQSEFNR----IMEYFERAIQRADFPPGVKVELAGESYLNYVLNDLVNEELGK 587 F+ VT + + FE+ ++ G + + G ++ + + L Sbjct: 501 DRTFLRVTVVPDDTLRADLAPAFEKRVRAVLEGSGSRFLVGGAPVGGREFSEAITDTLPT 560 Query: 588 ISTI---GTLIVVMVVFAIFRRPTVSIAMIMPMFLGA-----LWTI---GYMGLAGIPFS 636 + GT +++++ F P SI M + +GA W + + GL G+P S Sbjct: 561 VMLAVFGGTFVLLLLAFRSLLIPLKSIVM-NALTVGAAAGVVTWAVQEGHFAGLLGLPAS 619 Query: 637 QTLAGVV---------SMIVGLGVDYGMHITHRFLEELNEG--NKTPIITALESVGPGIF 685 AGV+ +++ GL +DY + + R EE G N ++ A+ I Sbjct: 620 ---AGVLDSSLPLLLFAVMFGLSMDYEIFLLSRVQEEHLAGASNDEAVVRAVGHTARIIT 676 Query: 686 VGALTTAGGFLALLSAQLTAIHDFGRVLAVGIFASMFAAYLV-TPAILQL 734 A+ F A + ++ A G LAV + LV PA L+L Sbjct: 677 SAAVIMFIVFTAFMFGRVVATKSVGLGLAVAVVLDATLVRLVLVPAFLKL 726 >sp|Q53902|MMLA_STRCO PUTATIVE MEMBRANE PROTEIN ACTII-3 >gi|80715|pir||C40046 antibiotic transport-associated protein actII-3 - Streptomyces coelicolor >gi|153146|gb|AAA26691.1| (M64683) ORF3 [Streptomyces coelicolor] Length = 711 Score = 75.3 bits (182), Expect = 2e-12 Identities = 55/214 (25%), Positives = 105/214 (48%), Gaps = 7/214 (3%) Query: 151 TIIIVNLNREKNQKALVRVYNDIEREIERTNFPQGVEVVLTGDLGITYKILEMLQNDMNR 210 T++ V+L ++ + L D+ R I R + P G+ V +TG G E + + Sbjct: 121 TVVNVHLGKD-GWEGLNAAAKDM-RAIARPSAPDGLGVHVTGPTGYAADSAESFSSADFK 178 Query: 211 TMAISGIIVVLILLYFYKSPIRMLVPLVPLIFGVVMTLGFMGLL----GIPLDIATTTV- 265 ++ +IVV IL+ Y+SP+ L+P++ +V++ + LL G+ ++ T + Sbjct: 179 LTLVTLLIVVTILVVTYRSPLLWLLPMISAGMSLVISQAIVYLLAKNAGLTVNAQTAMIL 238 Query: 266 GAMIIGMGIDYGVHVTNRYYEERGKGKSLEEAAEEAIAETGKALLGAALTTIAGFLALSI 325 +++G DY + + RY EE + + EA A+ G A++ +A T L L + Sbjct: 239 TVLVLGAATDYALLLVARYREELRRHEDRHEAMAVALRRAGPAIVASAATVAVSMLVLLL 298 Query: 326 SILPSLKRLSVSLVMGLGLAALNAVIVTPALAIL 359 + L S K L +G+ + L+ + + PAL ++ Sbjct: 299 AALNSTKGLGPVCAVGVLVGLLSMMTLLPALLVI 332 >pir||T23399 hypothetical protein K07C10.1 - Caenorhabditis elegans >gi|3878347|emb|CAA87375.1| (Z47074) similarity to transmembranous domains of the drosophila protein patched (Swiss Prot accession number P18502) [Caenorhabditis elegans] Length = 690 Score = 74.5 bits (180), Expect = 4e-12 Identities = 114/526 (21%), Positives = 206/526 (38%), Gaps = 60/526 (11%) Query: 251 MGLLGIPLDIATTTVGAMIIGMGIDYGVHVTNRYYEERGKGKSLEEAAEEAIAETGKALL 310 +G +G P + +I+G+G+D + N + E GK KS ++A + + Sbjct: 151 LGWVGHPFNSIMCITPFLILGIGVDDAFLLLNCWRREEGKDKSAKQAENQLARVIREISP 210 Query: 311 GAALTTIAGFLALSISILPSLKRLSVSLVMGLGLA-----ALNAVIVTPA---------- 355 A+T++ +A + L ++S S +G LA L +I P Sbjct: 211 SMAITSLTNTMAFGVGFLAPTPQMS-SFCLGTALAIVLDFLLEFLIFVPCMVLFYKKKPE 269 Query: 356 -LAILEEEF-REKVMKKKEIIAIGGGKSKISFIFSMLGKAIKRSPWTALLIALIIS--GV 411 +AI EEF EK K+ E G S+I+ + + P L+I L S Sbjct: 270 IIAIENEEFANEKTEKRSETST--GKYSRIN--WKCFTNLLLSVPGRVLVIILYFSIFTA 325 Query: 412 SLYGASKITTEVRLEKMIPTDLPEIQALSDIRSEFGGQDEVTILIKADDVRDPTLVRDI- 470 S +G +K+ K P+D + +L+ S + L D+++ T V + Sbjct: 326 SYFGVAKMEKTFDPSKTFPSDSKLVDSLASFTSIQVEYSPLNFLSSVPDLKNDTDVANFN 385 Query: 471 -----LRFEREIKADSYINNVF----ETQSIADVVIQKYGYIPQDKEKISEAIEGSSLVS 521 L F E D +N++ + + +++ + Y ++ + + A G+ Sbjct: 386 EMLHKLEFREECYGDVGSHNMYRDYVQFLNYSNITDKSYNHLEKFLKGRGMADVGTIKYH 445 Query: 522 SDYSMTIIKLKGNFMGVTQSEFNRIMEYFERAIQRADFPPGVKVELAGESYLNYVLNDLV 581 + + TII + NF+ V Q E+ +RA + L S N L D Sbjct: 446 KEGNDTIIDMI-NFVVVCQGR--------EKWAERAVNVEKTRQILVDYSDYNITLFDYD 496 Query: 582 NEELGKISTI-GTLIVVMVVFAIFRRPTVSIAMIMPMFLG-----------ALWTIGYMG 629 I T+ G L+ + + F T++ +IMP F+ + IG++ Sbjct: 497 GTIYDLIITVKGELVKSLAI--TFTCMTIACFVIMPSFVAPTIASVATVSISFCLIGFLS 554 Query: 630 LAGIPFSQTLAGVVSMIVGLGVDYGMHITHRF--LEELNEGNKTPIITA-LESVGPGIFV 686 + G V M +G VDY H+ + + E + G+K +IT+ L++VG + Sbjct: 555 IWGQNLDPVTMIDVIMAIGFSVDYSAHVCYHYYCAREQHLGSKHEVITSVLQAVGRPVVE 614 Query: 687 GALTTAGGFLALLSAQLTAIHDFGRVLAVGIFASMFAAYLVTPAIL 732 +LTT L + I F + + + + P +L Sbjct: 615 ASLTTLLCMAPLFVVPVYMIQSFAKTVTLVTSFGLLHGLFFLPVVL 660 >sp|P96706|YDGH_BACSU PUTATIVE MEMBRANE PROTEIN YDGH >gi|7475936|pir||B69783 transporter homolog ydgH - Bacillus subtilis >gi|1881371|dbj|BAA19398.1| (AB001488) PROBABLE TRANSPORT PROTEIN, SIMILAR PRODUCT IN MYCOBACTERIUM LEPRAE. [Bacillus subtilis] >gi|2632865|emb|CAB12372.1| (Z99106) similar to transporter [Bacillus subtilis] >gi|2632878|emb|CAB12384.1| (Z99107) similar to transporter [Bacillus subtilis] Length = 885 Score = 73.7 bits (178), Expect = 7e-12 Identities = 84/405 (20%), Positives = 176/405 (42%), Gaps = 31/405 (7%) Query: 123 KNMDEVKFVLNMLPPE--ARNGLISGDYSSTIIIVNL--NREKNQKALVRVYNDIEREIE 178 K +D V+ V + L E ++ L+S D + ++ V + + +K +K +Y + Sbjct: 90 KKIDGVEEVTSPLSAEKEVKDQLMSKDKKTVLMPVTITGSDKKAEKIADEIYQIV----- 144 Query: 179 RTNFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLVPLV 238 P + +TG I + + +T I+ +++ +LL ++S + +P+V Sbjct: 145 ----PDDLTAYITGASLINQDFAHSSEEGLKKTEVITVCLIIGLLLIVFRSVVTPFIPIV 200 Query: 239 PLIFGVVMTLGFMGLLGIPLDIATTT-----VGAMIIGMGIDYGVHVTNRYYEERGKGKS 293 + F +++ +G+L +D +T + A++ G+G DY + + R+ EE G Sbjct: 201 VVGFSYLISQSILGILVYNVDFPISTFTQTFLVAILFGIGTDYCILLLTRFREELANGHD 260 Query: 294 LEEAAEEAIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNAVIVT 353 +EAA A GK L + + GF AL + ++ + +V + +G+G+ + + Sbjct: 261 KKEAALIAYRTGGKTLFISGFAVLIGFSALGFAKF-AIFQSAVGVAVGVGILMIILYTLL 319 Query: 354 PALAILEEEFREKVMKKKEIIAIGGGKSKISFIFSMLGKAIKRSPWTALLIALIIS-GVS 412 P + E + K++++ K +++ LG+ P+ ++I ++I+ Sbjct: 320 PLFMVTLGE--KLFWPSKKVLSHSDNK-----LWAFLGRHSVARPFLFIVITVVITLPFI 372 Query: 413 LYGASKITTEVRLEKMIPTDLPEIQALSDIRSEFGGQDEVTILIKADDVRDPTLVRDILR 472 L +I+ + E I +D I+AL I+ FG I + +D T I Sbjct: 373 LTYDDQISFDSTAE--ISSDYKSIKALEAIKDGFGEGKAFPINVVVKGDKDLTTADTIPY 430 Query: 473 FEREIKADSYINNVFETQSIADVVIQKYG--YIPQDKEKISEAIE 515 KA +++V +I +K YI +S+ ++ Sbjct: 431 LGNISKAIEKVDHVDSVMTITQPTGKKIKDLYIDNQLGSVSDGLD 475 >emb|CAB86119.1| (AL163003) putative integral membrane protein [Streptomyces coelicolor A3(2)] Length = 743 Score = 73.4 bits (177), Expect = 9e-12 Identities = 61/248 (24%), Positives = 112/248 (44%), Gaps = 8/248 (3%) Query: 218 IVVLILLYFYKSPIRMLVPLVPLIFGVVMTLGFMGLLGIPLDI---ATTTVGAMIIGMGI 274 + +L+LL+ + S + L+PL + +V T + LLG I AT A+ +G+GI Sbjct: 186 LTLLLLLFVFGSVVSALLPLAIGLIAIVGTFAELFLLGSVASISITATNLTTALGLGLGI 245 Query: 275 DYGVHVTNRYYEERGKGKSLEEAAEEAIAETGKALLGAALTTIAGFLALSISILPSLKRL 334 DY + + +R+ E+ KG S+++A + G+ + +A T AL + L+ Sbjct: 246 DYALLMVSRFREQLAKGASVDDAVRHTVHTAGRTVAFSAATVAVALAALLVFPQYFLRSF 305 Query: 335 SVSLVMGLGLAALNAVIVTPALAILEEEFREKVMKKKEIIAIGGGKSKISFIFSMLGKAI 394 + V + +AA++ + V PAL + K S++ F + A+ Sbjct: 306 GYAGVGVVAIAAVSTLFVMPALLNVLGHRVNKGRLPWAGRTERHDDSRVPFWGRLARTAM 365 Query: 395 KRSPWTAL--LIALIISGVSLYGASKITTEVRLEKMIPTDLPEIQALSDIRSEFGGQDEV 452 +R TAL L L+++ L G I+ + E+ +P D Q + + F G D Sbjct: 366 RRPALTALPVLAVLLLAASPLLG---ISIGIADERSLPEDAASRQVSARLAENFNGSDAA 422 Query: 453 TILIKADD 460 + + D+ Sbjct: 423 AVHVVMDE 430 >sp|P95211|MML1_MYCTU PUTATIVE MEMBRANE PROTEIN MMPL1 >gi|7478394|pir||A70634 probable mmpL1 protein - Mycobacterium tuberculosis (strain H37RV) >gi|1817718|emb|CAB06593.1| (Z84725) mmpL1 [Mycobacterium tuberculosis] Length = 958 Score = 71.8 bits (173), Expect = 3e-11 Identities = 79/391 (20%), Positives = 151/391 (38%), Gaps = 34/391 (8%) Query: 117 ILGRLPKNMDEVKFVLNML-PPEARNGLISGDYSSTIIIVNLNREKNQKALVRVYNDIER 175 ++ +L ++ V+ + N P G S D + + +NL ++ ++R Sbjct: 101 LVTKLSQDTTHVQHIENFWGDPLTAAGSQSADGKAAYVQLNLTGDQGGSQANESVAAVQR 160 Query: 176 EIERTNFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVVLILLYFYKSPIRMLV 235 ++ P G++ +TG + + ++ IS ++ ++L Y+S L+ Sbjct: 161 IVDSVPPPPGIKAYVTGPGPLGADRVVYGDRSLHTITGISIAVIAIMLFIAYRSLSAALI 220 Query: 236 PLVPL------IFGVVMTLGFMGLLGIPLDIATTTVGAMIIGMGIDYGVHVTNRYYEERG 289 L+ + + G++ T L+G+ V A+ I DY + + RY E R Sbjct: 221 MLLTVGLELLAVRGIISTFAVNDLMGLSTFTVNVLV-ALTIAASTDYIIFLVGRYQEARA 279 Query: 290 KGKSLEEAAEEAIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLVMGLGLAALNA 349 G++ E A T +L + LT L + LP L+ +GL L + Sbjct: 280 TGQNREAAYYTMFGGTAHVVLASGLTVAGAMYCLGFTRLPYFNTLASPCAIGLVTVMLAS 339 Query: 350 VIVTPALAILEEEF-----REKVMKKKEIIAIGGGKSKISFIFSMLGKAIKRSPWTALLI 404 + + PA+ + F + K++ + +G + R P L Sbjct: 340 LTLAPAIIAVASRFGLFDPKRATTKRR---------------WRRIGTVVVRWPGPVLAA 384 Query: 405 ALIISGVSLYGASKITTEVRLEKMIPTDLPEI--QALSDIRSEFGGQDEVTILIKAD-DV 461 L+I+ + L K T IP+ P SD + ++++AD D+ Sbjct: 385 TLLIALIGLLALPKYQTNYNERYYIPSAAPSNIGYLASDRHFPQARMEPEVLMVEADHDL 444 Query: 462 RDPTLVRDILRFEREIKADSYINNVFETQSI 492 R+PT D+L +R K + + QSI Sbjct: 445 RNPT---DMLILDRIAKTVFHTPGIARVQSI 472 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.322 0.140 0.384 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 248335531 Number of Sequences: 2977 Number of extensions: 10391870 Number of successful extensions: 31594 Number of sequences better than 1.0e-10: 34 Number of HSP's better than 0.0 without gapping: 7 Number of HSP's successfully gapped in prelim test: 27 Number of HSP's that attempted gapping in prelim test: 31386 Number of HSP's gapped (non-prelim): 111 length of query: 746 length of database: 189,106,746 effective HSP length: 60 effective length of query: 686 effective length of database: 153,197,526 effective search space: 105093502836 effective search space used: 105093502836 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.9 bits) S2: 168 (69.9 bits)