BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB1104 (ppa) DE:THERMOSTABLE INORGANIC PYROPHOSPHATASE (EC 3.6.1.1) (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE). (178 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value sp|Q9UY24|IPYR_PYRAB INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PH... 375 e-103 sp|O59570|IPYR_PYRHO INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PH... 360 8e-99 sp|P77992|IPYR_THELI INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PH... 342 1e-93 sp|O26363|IPYR_METTH INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PH... 228 4e-59 sp|P37981|IPYR_THEAC INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PH... 187 7e-47 gb|AAG18854.1| (AE004989) inorganic pyrophosphatase; Ipp [Haloba... 180 1e-44 dbj|BAB05323.1| (AP001512) inorganic pyrophosphatase [Bacillus h... 177 8e-44 pir||JH0271 inorganic pyrophosphatase (EC 3.6.1.1) - Bacillus st... 176 1e-43 sp|O05724|IPYR_BACST INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PH... 176 1e-43 sp|P19514|IPYR_BACP3 INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PH... 174 6e-43 sp|O48556|IPYR_MAIZE SOLUBLE INORGANIC PYROPHOSPHATASE (PYROPHOS... 172 3e-42 sp|Q43187|IPYR_SOLTU SOLUBLE INORGANIC PYROPHOSPHATASE (PYROPHOS... 169 1e-41 gb|AAD46520.1|AF149116_1 (AF149116) soluble inorganic pyrophosph... 169 2e-41 pir||T01946 inorganic pyrophosphatase homolog F11O4.12 - Arabido... 168 4e-41 pir||T02201 probable inorganic pyrophosphatase (EC 3.6.1.1) - Ar... 168 4e-41 pir||T07399 probable inorganic pyrophosphatase (EC 3.6.1.1), sol... 166 2e-40 pir||T45902 inorganic pyrophosphatase-like protein - Arabidopsis... 166 2e-40 gb|AAD15513.1| (AC006439) putative inorganic pyrophosphatase [Ar... 166 2e-40 sp|P21216|IPYR_ARATH SOLUBLE INORGANIC PYROPHOSPHATASE (PYROPHOS... 165 3e-40 sp|O67501|IPYR_AQUAE INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PH... 165 3e-40 gb|AAC78101.1| (AF093629) inorganic pyrophosphatase [Oryza sativa] 164 6e-40 gb|AAF26475.1|AC007323_16 (AC007323) T25K16.5 [Arabidopsis thali... 162 2e-39 gb|AAF27918.1|AF220202_1 (AF220202) soluble inorganic pyrophosph... 159 2e-38 sp|P50308|IPYR_SULAC INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PH... 158 5e-38 pir||S76172 inorganic pyrophosphatase (EC 3.6.1.1) slr1622 [simi... 156 1e-37 sp|P80507|IPYR_SYNY3 INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PH... 156 1e-37 sp|O23979|IPYR_HORVD SOLUBLE INORGANIC PYROPHOSPHATASE (PYROPHOS... 154 7e-37 pir||H72550 probable inorganic pyrophosphatase APE1692 - Aeropyr... 153 2e-36 sp|Q9YBA5|IPYR_AERPE INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PH... 153 2e-36 pir||JE0392 inorganic pyrophosphatase (EC 3.6.1.1) - Sulfolobus ... 152 3e-36 sp|O69540|IPYR_MYCLE INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PH... 152 4e-36 sp|O06379|IPYR_MYCTU INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PH... 150 1e-35 gb|AAG31654.1| (AF315738) PRLI-interacting factor F [Arabidopsis... 150 1e-35 gb|AAK42538.1| Inorganic pyrophosphatase, putative (ppa) [Sulfol... 146 2e-34 pir||C83141 inorganic pyrophosphatase PA4031 [imported] - Pseudo... 141 5e-33 sp|O22537|IPYR_ORYSA SOLUBLE INORGANIC PYROPHOSPHATASE (PYROPHOS... 140 1e-32 pdb|2PRD| Mol_id: 1; Molecule: Pyrophosphate Phosphohydrolase;... 139 3e-32 sp|P38576|IPYR_THETH INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PH... 139 3e-32 sp|Q9X8I9|IPYR_STRCO INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PH... 136 2e-31 pir||H82589 inorganic pyrophosphatase XF2171 [imported] - Xylell... 136 2e-31 sp|P17288|IPYR_ECOLI INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PH... 136 2e-31 pdb|1JFD|A Chain A, Structure Of Inorganic Pyrophosphatase >gi|2... 136 2e-31 pdb|1OBW|A Chain A, Structure Of Inorganic Pyrophosphatase >gi|2... 134 9e-31 pdb|1MJW|A Chain A, Structure Of Inorganic Pyrophosphatase Mutan... 134 9e-31 pdb|1MJX|A Chain A, Structure Of Inorganic Pyrophosphatase Mutan... 134 9e-31 pdb|1MJZ| Structure Of Inorganic Pyrophosphatase Mutant D97n 134 9e-31 sp|O34955|IPYR_LEGPN INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PH... 132 2e-30 pdb|1MJY|A Chain A, Structure Of Inorganic Pyrophosphatase Mutan... 132 3e-30 sp|O05545|IPYR_GLUSU INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PH... 130 1e-29 pir||C82064 inorganic pyrophosphatase VC2545 [imported] - Vibrio... 129 2e-29 sp|P51064|IPYR_BARBA INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PH... 120 8e-27 sp|Q9ZLL5|IPYR_HELPJ INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PH... 120 1e-26 sp|P56153|IPYR_HELPY INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PH... 119 2e-26 sp|P47593|IPYR_MYCGE INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PH... 117 7e-26 sp|P75250|IPYR_MYCPN INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PH... 117 7e-26 pir||E81412 inorganic pyrophosphatase (EC 3.6.1.1) Cj0638c [impo... 113 1e-24 sp|P57190|IPYR_BUCAI INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PH... 111 7e-24 sp|Q9RGQ1|IPYR_RHORU INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PH... 107 8e-23 pir||B82908 inorganic pyrophosphatase UU315 [imported] - Ureapla... 107 1e-22 sp|Q9ZCW5|IPYR_RICPR INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PH... 106 2e-22 emb|CAB37742.1| (AJ239631) inorganic pyrophosphatase [Helicobact... 106 2e-22 emb|CAB37755.1| (AJ239644) inorganic pyrophosphatase [Helicobact... 106 2e-22 emb|CAB37740.1| (AJ239629) inorganic pyrophosphatase [Helicobact... 105 3e-22 emb|CAB37738.1| (AJ239627) inorganic pyrophosphatase [Helicobact... 104 5e-22 emb|CAB37739.1| (AJ239628) inorganic pyrophosphatase [Helicobact... 104 5e-22 emb|CAB37737.1| (AJ239626) inorganic pyrophosphatase [Helicobact... 104 7e-22 emb|CAB37748.1| (AJ239637) inorganic pyrophosphatase [Helicobact... 104 9e-22 emb|CAB37751.1| (AJ239640) inorganic pyrophosphatase [Helicobact... 104 9e-22 pir||F81175 inorganic pyrophosphatase NMB0641 [imported] - Neiss... 104 9e-22 emb|CAB37745.1| (AJ239634) inorganic pyrophosphatase [Helicobact... 102 2e-21 pir||G81930 probable inorganic pyrophosphatase (EC 3.6.1.1) NMA0... 101 6e-21 sp|P44529|IPYR_HAEIN INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PH... 96 3e-19 pir||A81736 inorganic pyrophosphatase, probable TC0153 [imported... 89 3e-17 sp|Q9Z6Y8|IPYR_CHLPN INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PH... 89 3e-17 sp|P37980|IPYR_BOVIN INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PH... 84 9e-16 sp|O84777|IPYR_CHLTR INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PH... 84 1e-15 gb|AAD24964.1| (AF108211) cytosolic inorganic pyrophosphatase [H... 81 8e-15 gi|11056044 pyrophosphatase (inorganic); inorganic pyrophosphata... 81 8e-15 gb|AAD50298.1|AF174582_1 (AF174582) inorganic pyrophosphatase [T... 79 3e-14 pir||S77798 probable inorganic pyrophosphatase (EC 3.6.1.1) - My... 79 4e-14 emb|CAA83823.1| (Z33286) inorganic pyrophosphatase [Mycoplasma c... 78 5e-14 pir||T49933 inorganic pyrophosphatase-like protein - Arabidopsis... 74 1e-12 pdb|8PRK|B Chain B, The R78k And D117e Active Site Variants Of S... 72 4e-12 sp|P00817|IPYR_YEAST INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PH... 71 9e-12 gi|6319483 Inorganic pyrophosphatase; Ipp1p [Saccharomyces cerev... 71 9e-12 pdb|1WGJ|B Chain B, Structure Of Inorganic Pyrophosphatase >gi|2... 71 9e-12 pdb|1HUJ|A Chain A, Refined Structure Of Yeast Inorganic Pyropho... 71 9e-12 pdb|1HUK|A Chain A, Refined Structure Of Yeast Inorganic Pyropho... 71 9e-12 pir||T20014 hypothetical protein C47E12.4 - Caenorhabditis elega... 71 1e-11 sp|Q18680|IPYR_CAEEL PROBABLE INORGANIC PYROPHOSPHATASE (PYROPHO... 71 1e-11 sp|P13998|IPYR_KLULA INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PH... 70 2e-11 pdb|1PYP| Inorganic Pyrophosphatase (E.C.3.6.1.1) 70 2e-11 pdb|117E|A Chain A, The R78k And D117e Active Site Variants Of S... 69 3e-11 pdb|1YPP|A Chain A, Acid Anhydride Hydrolase >gi|1942887|pdb|1YP... 69 3e-11 sp|O77460|IPYR_DROME INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PH... 69 4e-11 sp|O13505|IPYR_PICPA INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PH... 68 6e-11 pir||T51225 related to INORGANIC PYROPHOSPHATASE [imported] - Ne... 68 7e-11 >sp|Q9UY24|IPYR_PYRAB INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) >gi|7436040|pir||F75018 inorganic pyrophosphatase (EC 3.6.1.1) PAB1104 [similarity] - Pyrococcus abyssi (strain Orsay) >gi|5459102|emb|CAB50588.1| (AJ248288) THERMOSTABLE INORGANIC PYROPHOSPHATASE (EC 3.6.1.1) (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE). [Pyrococcus abyssi] Length = 178 Score = 375 bits (953), Expect = e-103 Identities = 178/178 (100%), Positives = 178/178 (100%) Query: 1 MNPFHDLEPGPNVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIP 60 MNPFHDLEPGPNVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIP Sbjct: 1 MNPFHDLEPGPNVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIP 60 Query: 61 RTWYDDDDPFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKDWK 120 RTWYDDDDPFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKDWK Sbjct: 61 RTWYDDDDPFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKDWK 120 Query: 121 DIDDVPKAFLDEIAHFFKRYKELQGKEIIVEGWEGAEAAKREILRAIELYKEKFGSKE 178 DIDDVPKAFLDEIAHFFKRYKELQGKEIIVEGWEGAEAAKREILRAIELYKEKFGSKE Sbjct: 121 DIDDVPKAFLDEIAHFFKRYKELQGKEIIVEGWEGAEAAKREILRAIELYKEKFGSKE 178 >sp|O59570|IPYR_PYRHO INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) >gi|7436022|pir||A71205 inorganic pyrophosphatase (EC 3.6.1.1) PH1907 [similarity] - Pyrococcus horikoshii >gi|3258349|dbj|BAA31032.1| (AP000007) 178aa long hypothetical inorganic pyrophosphatase [Pyrococcus horikoshii] Length = 178 Score = 360 bits (913), Expect = 8e-99 Identities = 169/178 (94%), Positives = 174/178 (96%) Query: 1 MNPFHDLEPGPNVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIP 60 MNPFHDLEPGPNVPEVVYALIEIPKGSRNKYELDK+TGLLKLDRVLY+PF YPVDYGIIP Sbjct: 1 MNPFHDLEPGPNVPEVVYALIEIPKGSRNKYELDKETGLLKLDRVLYTPFHYPVDYGIIP 60 Query: 61 RTWYDDDDPFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKDWK 120 RTWY+D DPFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKDWK Sbjct: 61 RTWYEDGDPFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKDWK 120 Query: 121 DIDDVPKAFLDEIAHFFKRYKELQGKEIIVEGWEGAEAAKREILRAIELYKEKFGSKE 178 DI DVPKAFLDEIAHFFKRYKEL+GKEIIVEGWEGAEAAKREILRAIE+YKEKFG KE Sbjct: 121 DISDVPKAFLDEIAHFFKRYKELEGKEIIVEGWEGAEAAKREILRAIEMYKEKFGKKE 178 >sp|P77992|IPYR_THELI INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) >gi|1518483|gb|AAB07349.1| (U49440) thermostable inorganic pyrophosphatase [Thermococcus litoralis] Length = 176 Score = 342 bits (869), Expect = 1e-93 Identities = 161/174 (92%), Positives = 166/174 (94%) Query: 1 MNPFHDLEPGPNVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIP 60 MNPFHDLEPGP VPEVVYALIEIPKGSRNKYELDKKTGL+KLDRVLYSPF YPVDYGIIP Sbjct: 1 MNPFHDLEPGPEVPEVVYALIEIPKGSRNKYELDKKTGLIKLDRVLYSPFHYPVDYGIIP 60 Query: 61 RTWYDDDDPFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKDWK 120 +TWYDDDDPFDIMVIMREPTYP +IEARPIGLFKMIDSGDKDYKVLAVPVEDPYF DWK Sbjct: 61 QTWYDDDDPFDIMVIMREPTYPGVLIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFNDWK 120 Query: 121 DIDDVPKAFLDEIAHFFKRYKELQGKEIIVEGWEGAEAAKREILRAIELYKEKF 174 DI DVPKAFLDEIAHFF+RYKELQGKEIIVEGWE AE AK+EILRAIELYKEKF Sbjct: 121 DISDVPKAFLDEIAHFFQRYKELQGKEIIVEGWENAEKAKQEILRAIELYKEKF 174 >sp|O26363|IPYR_METTH INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) >gi|7436025|pir||B69133 inorganic pyrophosphatase (EC 3.6.1.1) MTH263 [similarity] - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2621313|gb|AAB84769.1| (AE000812) inorganic pyrophosphatase [Methanobacterium thermoautotrophicum] Length = 176 Score = 228 bits (575), Expect = 4e-59 Identities = 108/174 (62%), Positives = 134/174 (76%) Query: 1 MNPFHDLEPGPNVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIP 60 MN + D+EPGP+VPEVVYA++EIPKGSRNKYE K LDRVLYS FYP +YGIIP Sbjct: 1 MNLWKDIEPGPSVPEVVYAVVEIPKGSRNKYEYHKDLQAFALDRVLYSAVFYPAEYGIIP 60 Query: 61 RTWYDDDDPFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKDWK 120 RT YDD DP DI+V+M EPT+P IIE+RPIGL +MID GD+D K+LAVPV DP+F D K Sbjct: 61 RTLYDDGDPMDILVLMDEPTFPGCIIESRPIGLLRMIDGGDQDDKILAVPVADPHFADVK 120 Query: 121 DIDDVPKAFLDEIAHFFKRYKELQGKEIIVEGWEGAEAAKREILRAIELYKEKF 174 DI D+P+ L EIA+FF+ YK+L+GK+ GWEGAE A + +IELY++K+ Sbjct: 121 DISDIPEHNLKEIANFFETYKKLEGKKTETLGWEGAEKAFEAVNHSIELYRKKY 174 >sp|P37981|IPYR_THEAC INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) >gi|478783|pir||S29313 inorganic pyrophosphatase (EC 3.6.1.1), cytosolic [validated] - Thermoplasma acidophilum >gi|48082|emb|CAA45525.1| (X64200) inorganic pyrophosphatase [Thermoplasma acidophilum] >gi|10639570|emb|CAC11542.1| (AL445064) inorganic pyrophosphatase [Thermoplasma acidophilum] Length = 179 Score = 187 bits (470), Expect = 7e-47 Identities = 91/174 (52%), Positives = 121/174 (69%) Query: 4 FHDLEPGPNVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTW 63 +H + GP PE VY ++EIP+GSR KYE+ K + +DRVLYS YPVDYG+IPRT Sbjct: 5 YHSVPVGPKPPEEVYVIVEIPRGSRVKYEIAKDFPGMLVDRVLYSSVVYPVDYGLIPRTL 64 Query: 64 YDDDDPFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKDWKDID 123 Y D DP D+MV++ +PT+P I++ RPIG+ KM+D G+ D K+LAV +DP KD+ Sbjct: 65 YYDGDPMDVMVLISQPTFPGAIMKVRPIGMMKMVDQGETDNKILAVFDKDPNVSYIKDLK 124 Query: 124 DVPKAFLDEIAHFFKRYKELQGKEIIVEGWEGAEAAKREILRAIELYKEKFGSK 177 DV LDEIA+FF YK L+ KE V GWEG EAA +EI +I++Y+EK+G K Sbjct: 125 DVNAHLLDEIANFFSTYKILEKKETKVLGWEGKEAALKEIEVSIKMYEEKYGKK 178 >gb|AAG18854.1| (AE004989) inorganic pyrophosphatase; Ipp [Halobacterium sp. NRC-1] Length = 177 Score = 180 bits (451), Expect = 1e-44 Identities = 88/174 (50%), Positives = 120/174 (68%), Gaps = 1/174 (0%) Query: 2 NPFHDLEPGPNVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPR 61 N + DLE GP+ P+V+YA++E KG RNKYE DK + LDRVL+S YP DYG IP+ Sbjct: 3 NLWEDLETGPDAPDVIYAVVECLKGERNKYEYDKDIPGVVLDRVLHSNVHYPSDYGFIPQ 62 Query: 62 TWYDDDDPFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKDWKD 121 ++YDD DPFD++V++ + T+P +IEARP+ L +M D G++D KV+AVP EDP + D +D Sbjct: 63 SYYDDGDPFDVLVLVEDQTFPGCVIEARPVALMEMDDDGEQDDKVIAVPEEDPRYDDVED 122 Query: 122 IDDVPKAFLDEIAHFFKRYKELQG-KEIIVEGWEGAEAAKREILRAIELYKEKF 174 +DD+ EIA FF+ YK L+ KE V GW A+AAK I A +LY E+F Sbjct: 123 VDDLTDQQKAEIAEFFETYKNLEADKETAVLGWGDAQAAKDAIEHAQDLYDEQF 176 >dbj|BAB05323.1| (AP001512) inorganic pyrophosphatase [Bacillus halodurans] Length = 163 Score = 177 bits (444), Expect = 8e-44 Identities = 84/158 (53%), Positives = 111/158 (70%) Query: 14 PEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDDDDPFDIM 73 P+V+ A IEIP GS+NKYE DK+ G+ KLDRVL+SP FYP +YG I T D DP D++ Sbjct: 5 PKVIEAFIEIPTGSQNKYEYDKERGVFKLDRVLFSPMFYPAEYGYIENTLALDGDPLDVL 64 Query: 74 VIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKDWKDIDDVPKAFLDEI 133 VI+ PT+P +I+A+ +G MID G++D K++AVP EDP FKD ++D+PK LDEI Sbjct: 65 VIVSNPTFPGCVIDAKVLGFLNMIDGGEEDQKLIAVPTEDPRFKDVNSLNDLPKHKLDEI 124 Query: 134 AHFFKRYKELQGKEIIVEGWEGAEAAKREILRAIELYK 171 AHFFK YK+L+GK+ V +E AEAA + I YK Sbjct: 125 AHFFKTYKDLEGKKTEVGAYEDAEAAAKLIDECFARYK 162 >pir||JH0271 inorganic pyrophosphatase (EC 3.6.1.1) - Bacillus stearothermophilus >gi|2059312|dbj|BAA19837.1| (AB003087) Pyrophosphatase [Bacillus stearothermophilus] Length = 164 Score = 176 bits (443), Expect = 1e-43 Identities = 84/159 (52%), Positives = 110/159 (68%) Query: 15 EVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDDDDPFDIMV 74 ++V A IEIP GS+NKYE DK+ G+ KLDRVLYSP FYP +YG + T D DP DI+V Sbjct: 5 KIVEAFIEIPTGSQNKYEFDKERGIFKLDRVLYSPMFYPAEYGYLQNTLALDGDPLDILV 64 Query: 75 IMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKDWKDIDDVPKAFLDEIA 134 I PT+P +I+ R IG M+DSG++D K++ VPVEDP F + + I+D+P+ L EIA Sbjct: 65 ITTNPTFPGCVIDTRVIGYLNMVDSGEEDAKLIGVPVEDPRFDEVRSIEDLPQHKLKEIA 124 Query: 135 HFFKRYKELQGKEIIVEGWEGAEAAKREILRAIELYKEK 173 HFF+RYK+LQGK + WEG EAA + I I Y E+ Sbjct: 125 HFFERYKDLQGKRTEIGTWEGPEAAAKLIDECIARYNEQ 163 >sp|O05724|IPYR_BACST INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) Length = 165 Score = 176 bits (443), Expect = 1e-43 Identities = 84/159 (52%), Positives = 110/159 (68%) Query: 15 EVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDDDDPFDIMV 74 ++V A IEIP GS+NKYE DK+ G+ KLDRVLYSP FYP +YG + T D DP DI+V Sbjct: 6 KIVEAFIEIPTGSQNKYEFDKERGIFKLDRVLYSPMFYPAEYGYLQNTLALDGDPLDILV 65 Query: 75 IMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKDWKDIDDVPKAFLDEIA 134 I PT+P +I+ R IG M+DSG++D K++ VPVEDP F + + I+D+P+ L EIA Sbjct: 66 ITTNPTFPGCVIDTRVIGYLNMVDSGEEDAKLIGVPVEDPRFDEVRSIEDLPQHKLKEIA 125 Query: 135 HFFKRYKELQGKEIIVEGWEGAEAAKREILRAIELYKEK 173 HFF+RYK+LQGK + WEG EAA + I I Y E+ Sbjct: 126 HFFERYKDLQGKRTEIGTWEGPEAAAKLIDECIARYNEQ 164 >sp|P19514|IPYR_BACP3 INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) >gi|77465|pir||JX0135 inorganic pyrophosphatase (EC 3.6.1.1) - thermophilic bacterium PS-3 Length = 164 Score = 174 bits (437), Expect = 6e-43 Identities = 83/159 (52%), Positives = 109/159 (68%) Query: 15 EVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDDDDPFDIMV 74 ++V A IEIP GS+NKYE DK+ G+ KLDRVLYSP FYP +YG + T D DP DI+V Sbjct: 5 KIVEAFIEIPTGSQNKYEFDKERGIFKLDRVLYSPMFYPAEYGYLQNTLALDGDPLDILV 64 Query: 75 IMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKDWKDIDDVPKAFLDEIA 134 I P +P +I+ R IG M+DSG++D K++ VPVEDP F + + I+D+P+ L EIA Sbjct: 65 ITTNPPFPGCVIDTRVIGYLNMVDSGEEDAKLIGVPVEDPRFDEVRSIEDLPQHKLKEIA 124 Query: 135 HFFKRYKELQGKEIIVEGWEGAEAAKREILRAIELYKEK 173 HFF+RYK+LQGK + WEG EAA + I I Y E+ Sbjct: 125 HFFERYKDLQGKRTEIGTWEGPEAAAKLIDECIARYNEQ 163 >sp|O48556|IPYR_MAIZE SOLUBLE INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) >gi|7436036|pir||T01370 inorganic pyrophosphatase (EC 3.6.1.1) - maize >gi|2668746|gb|AAB88618.1| (AF034947) inorganic pyrophosphatase [Zea mays] Length = 214 Score = 172 bits (431), Expect = 3e-42 Identities = 80/171 (46%), Positives = 118/171 (68%) Query: 2 NPFHDLEPGPNVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPR 61 +P+HDLE GP+ P V ++EI KGS+ KYELDKKTGL+K+DRVLYS YP +YG +PR Sbjct: 36 HPWHDLEIGPDAPAVFNVVVEITKGSKVKYELDKKTGLIKVDRVLYSSVVYPHNYGFVPR 95 Query: 62 TWYDDDDPFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKDWKD 121 T +D+DP D++V+M+EP P + + AR IGL MID G+KD K++AV +DP ++ + D Sbjct: 96 TLCEDNDPMDVLVLMQEPVVPGSFLRARAIGLMPMIDQGEKDDKIIAVCADDPEYRHYND 155 Query: 122 IDDVPKAFLDEIAHFFKRYKELQGKEIIVEGWEGAEAAKREILRAIELYKE 172 I ++ L EI FF+ YK+ + KE+ V+ + A A+ I +++LY + Sbjct: 156 ISELSPHRLQEIKRFFEDYKKNENKEVAVDAFLPATTAREAIQYSMDLYAQ 206 >sp|Q43187|IPYR_SOLTU SOLUBLE INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) >gi|7436030|pir||T07594 probable inorganic pyrophosphatase (EC 3.6.1.1), soluble PPA - potato >gi|534916|emb|CAA85362.1| (Z36894) soluble inorganic pyrophosphatase [Solanum tuberosum] Length = 211 Score = 169 bits (425), Expect = 1e-41 Identities = 81/171 (47%), Positives = 115/171 (66%) Query: 2 NPFHDLEPGPNVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPR 61 +P+HDLE GP P V +IEI KGS+ KYELDKKTGL+K+DR+LYS YP +YG IPR Sbjct: 33 HPWHDLEIGPEAPSVFNVVIEISKGSKVKYELDKKTGLIKVDRILYSSVVYPQNYGFIPR 92 Query: 62 TWYDDDDPFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKDWKD 121 T +D+DP D++V+M+EP P + AR IGL MID G+KD K++AV +DP ++ + D Sbjct: 93 TLCEDNDPMDVLVLMQEPVLPGCFLRARAIGLMPMIDQGEKDDKIIAVCADDPEYRHYTD 152 Query: 122 IDDVPKAFLDEIAHFFKRYKELQGKEIIVEGWEGAEAAKREILRAIELYKE 172 I +P L EI FF+ YK+ + K++ V+ + +A I +++LY E Sbjct: 153 IKQLPPHRLAEIRRFFEDYKKNENKDVAVDDFLPPNSAVNAIQYSMDLYAE 203 >gb|AAD46520.1|AF149116_1 (AF149116) soluble inorganic pyrophosphatase [Populus tremula x Populus tremuloides] Length = 215 Score = 169 bits (423), Expect = 2e-41 Identities = 80/171 (46%), Positives = 114/171 (65%) Query: 2 NPFHDLEPGPNVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPR 61 +P+HDLE GP P + ++EI KGS+ KYELDKKTGL+K+DR+LYS YP +YG IPR Sbjct: 37 HPWHDLEIGPGAPHIFNVVVEITKGSKVKYELDKKTGLIKVDRILYSSVVYPHNYGFIPR 96 Query: 62 TWYDDDDPFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKDWKD 121 T +D+DP D++V+M+EP P + AR IGL MID G+KD K++AV +DP +K + D Sbjct: 97 TLCEDNDPLDVLVLMQEPVLPGCFLRARAIGLMPMIDQGEKDDKIIAVCADDPEYKHYTD 156 Query: 122 IDDVPKAFLDEIAHFFKRYKELQGKEIIVEGWEGAEAAKREILRAIELYKE 172 I ++ L EI FF+ YK+ + KE+ V + + A I +++LY E Sbjct: 157 IKELAPHRLSEIRRFFEDYKKNENKEVAVNDFLPSNTAVEAIQYSMDLYAE 207 >pir||T01946 inorganic pyrophosphatase homolog F11O4.12 - Arabidopsis thaliana >gi|3695383|gb|AAC62786.1| (AF096370) similar to inorganic pyrophosphatase (Pfam: PF00719 Pyrophosphatase, E-value: 2.7e-88) [Arabidopsis thaliana] >gi|7268191|emb|CAB77718.1| (AL161492) putative inorganic phosphatase [Arabidopsis thaliana] Length = 216 Score = 168 bits (421), Expect = 4e-41 Identities = 82/171 (47%), Positives = 115/171 (66%) Query: 2 NPFHDLEPGPNVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPR 61 +P+HDLE GP P + +IEI KGS+ KYELDKKTGL+K+DR+LYS YP +YG +PR Sbjct: 38 HPWHDLEIGPGAPVIFNVVIEISKGSKVKYELDKKTGLIKVDRILYSSVVYPHNYGFVPR 97 Query: 62 TWYDDDDPFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKDWKD 121 T +D+DP D++VIM+EP P + AR IGL MID G+KD K++AV V+DP +K + Sbjct: 98 TLCEDNDPIDVLVIMQEPVLPGCFLRARAIGLMPMIDQGEKDDKIIAVCVDDPEYKHITN 157 Query: 122 IDDVPKAFLDEIAHFFKRYKELQGKEIIVEGWEGAEAAKREILRAIELYKE 172 I+++P L EI FF+ YK+ + KE+ V + A I +++LY E Sbjct: 158 INELPPHRLSEIRRFFEDYKKNENKEVAVNDFLQPGPAIEAIQYSMDLYAE 208 >pir||T02201 probable inorganic pyrophosphatase (EC 3.6.1.1) - Arabidopsis thaliana >gi|3522960|gb|AAC34242.1| (AC004411) putative inorganic pyrophosphatase [Arabidopsis thaliana] Length = 216 Score = 168 bits (421), Expect = 4e-41 Identities = 81/171 (47%), Positives = 115/171 (66%) Query: 2 NPFHDLEPGPNVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPR 61 +P+HDLE GP P V ++EI KGS+ KYELDKKTGL+K+DR+LYS YP +YG IPR Sbjct: 38 HPWHDLEIGPEAPLVFNVVVEITKGSKVKYELDKKTGLIKVDRILYSSVVYPHNYGFIPR 97 Query: 62 TWYDDDDPFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKDWKD 121 T +D+DP D++V+M+EP P + AR IGL MID G+KD K++AV +DP +K + D Sbjct: 98 TLCEDNDPLDVLVLMQEPVLPGCFLRARAIGLMPMIDQGEKDDKIIAVCADDPEYKHFTD 157 Query: 122 IDDVPKAFLDEIAHFFKRYKELQGKEIIVEGWEGAEAAKREILRAIELYKE 172 I + L EI FF+ YK+ + K++ V + +E+A I +++LY E Sbjct: 158 IKQLAPHRLQEIRRFFEDYKKNENKKVAVNDFLPSESAHEAIQYSMDLYAE 208 >pir||T07399 probable inorganic pyrophosphatase (EC 3.6.1.1), soluble - potato >gi|2706450|emb|CAA12415.1| (AJ225172) magnesium dependent soluble inorganic pyrophosphatase [Solanum tuberosum] Length = 217 Score = 166 bits (416), Expect = 2e-40 Identities = 81/172 (47%), Positives = 118/172 (68%), Gaps = 1/172 (0%) Query: 2 NPFHDLEPGPNVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPR 61 +P+HDLE P+ P++ +IEI KGS+ KYELDKKTGL+K+DRVLYS YP +YG IPR Sbjct: 38 HPWHDLEIEPDAPQIFNVVIEISKGSKVKYELDKKTGLIKVDRVLYSSVVYPHNYGFIPR 97 Query: 62 TWYDDDDPFDIMVIMREP-TYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKDWK 120 T +D DP D++VIM+EP T L + A+ IG+ MID G+KD K++AV +DP +KD+ Sbjct: 98 TLCEDSDPLDVLVIMQEPITSGLDFLRAKAIGVMPMIDQGEKDEKIIAVCADDPEYKDYA 157 Query: 121 DIDDVPKAFLDEIAHFFKRYKELQGKEIIVEGWEGAEAAKREILRAIELYKE 172 DI+++P L EI FF+ YK+ + KE+ V + ++ A + + +LY + Sbjct: 158 DINELPPHRLAEIRRFFEDYKKNENKEVAVNDFLPSDKAFEAVQHSQDLYAD 209 >pir||T45902 inorganic pyrophosphatase-like protein - Arabidopsis thaliana >gi|6729513|emb|CAB67669.1| (AL132966) inorganic pyrophosphatase-like protein [Arabidopsis thaliana] Length = 216 Score = 166 bits (416), Expect = 2e-40 Identities = 78/171 (45%), Positives = 114/171 (66%) Query: 2 NPFHDLEPGPNVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPR 61 +P+HDLE GP P + ++EI KGS+ KYELDK TGL+K+DR+LYS YP +YG IPR Sbjct: 38 HPWHDLEIGPEAPIIFNCVVEIGKGSKVKYELDKTTGLIKVDRILYSSVVYPHNYGFIPR 97 Query: 62 TWYDDDDPFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKDWKD 121 T +D DP D++VIM+EP P + A+ IGL MID G+KD K++AV +DP ++ + D Sbjct: 98 TLCEDSDPIDVLVIMQEPVIPGCFLRAKAIGLMPMIDQGEKDDKIIAVCADDPEYRHYND 157 Query: 122 IDDVPKAFLDEIAHFFKRYKELQGKEIIVEGWEGAEAAKREILRAIELYKE 172 I ++P + EI FF+ YK+ + KE+ V + A AA + +++LY + Sbjct: 158 ISELPPHRMAEIRRFFEDYKKNENKEVAVNDFLPATAAYDAVQHSMDLYAD 208 >gb|AAD15513.1| (AC006439) putative inorganic pyrophosphatase [Arabidopsis thaliana] Length = 218 Score = 166 bits (415), Expect = 2e-40 Identities = 80/169 (47%), Positives = 115/169 (67%) Query: 2 NPFHDLEPGPNVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPR 61 +P+HDLE GP P V ++EI KG + KYELDK +GL+K+DRVLYS YP +YG IPR Sbjct: 40 HPWHDLEIGPEAPTVFNCVVEISKGGKVKYELDKNSGLIKVDRVLYSSIVYPHNYGFIPR 99 Query: 62 TWYDDDDPFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKDWKD 121 T +D DP D++V+M+EP + + AR IGL MID G+KD K++AV +DP F+ ++D Sbjct: 100 TICEDSDPMDVLVLMQEPVLTGSFLRARAIGLMPMIDQGEKDDKIIAVCADDPEFRHYRD 159 Query: 122 IDDVPKAFLDEIAHFFKRYKELQGKEIIVEGWEGAEAAKREILRAIELY 170 I ++P L EI FF+ YK+ + K++ VE + A+AA I +++LY Sbjct: 160 IKELPPHRLAEIRRFFEDYKKNENKKVDVEAFLPAQAAIDAIKDSMDLY 208 >sp|P21216|IPYR_ARATH SOLUBLE INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) >gi|81645|pir||S13379 inorganic pyrophosphatase (EC 3.6.1.1) - Arabidopsis thaliana >gi|16348|emb|CAA40764.1| (X57545) inorganic pyrophosphatase [Arabidopsis thaliana] Length = 263 Score = 165 bits (414), Expect = 3e-40 Identities = 80/170 (47%), Positives = 115/170 (67%) Query: 2 NPFHDLEPGPNVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPR 61 +P+HDLE GP P V +EI KG + KYELDK +GL+K+DRVLYS YP +YG IPR Sbjct: 40 HPWHDLEIGPEAPTVFNCAVEISKGGKVKYELDKNSGLIKVDRVLYSSIVYPHNYGFIPR 99 Query: 62 TWYDDDDPFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKDWKD 121 T +D DP D++V+M+EP + + AR IGL MID G+KD K++AV +DP F+ ++D Sbjct: 100 TICEDSDPMDVLVLMQEPVLTGSFLRARAIGLMPMIDQGEKDDKIIAVCADDPEFRHYRD 159 Query: 122 IDDVPKAFLDEIAHFFKRYKELQGKEIIVEGWEGAEAAKREILRAIELYK 171 I ++P L EI FF+ YK+ + K++ VE + A+AA I +++LY+ Sbjct: 160 IKELPPHRLAEIRRFFEDYKKNENKKVDVEAFLPAQAAIDAIKDSMDLYE 209 >sp|O67501|IPYR_AQUAE INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) >gi|7436020|pir||C70434 inorganic pyrophosphatase - Aquifex aeolicus >gi|2983913|gb|AAC07463.1| (AE000745) inorganic pyrophosphatase [Aquifex aeolicus] Length = 178 Score = 165 bits (414), Expect = 3e-40 Identities = 80/172 (46%), Positives = 115/172 (66%), Gaps = 3/172 (1%) Query: 4 FHDLEPGPNVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTW 63 + L PG N PE +Y +IEIP+GS KYELDK TG++ +DR L++ +YP +YG +P+T Sbjct: 3 YDQLPPGKNPPEDIYVVIEIPQGSAVKYELDKDTGVIFVDRFLFTAMYYPFNYGFVPQTL 62 Query: 64 YDDDDPFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVE--DPYFKDWKD 121 DD DP D++VI REP P ++ RPIG+ +M D D KV+AVP E DP + + K Sbjct: 63 ADDGDPVDVLVISREPVVPGAVMRCRPIGMLEMRDEAGIDTKVIAVPHEKLDPSYSNIKT 122 Query: 122 IDDVPKAFLDEIAHFFKRYKELQ-GKEIIVEGWEGAEAAKREILRAIELYKE 172 +D++P+ ++I HFF+ YKEL+ GK + VE W+G + A EI + IE YK+ Sbjct: 123 VDNLPEIVREKIKHFFEHYKELEPGKWVKVENWKGLQDAIEEIKKGIENYKK 174 >gb|AAC78101.1| (AF093629) inorganic pyrophosphatase [Oryza sativa] Length = 214 Score = 164 bits (411), Expect = 6e-40 Identities = 80/169 (47%), Positives = 113/169 (66%) Query: 2 NPFHDLEPGPNVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPR 61 +P+HDLE GP P V ++EIP+GS+ KYELDK TGL+K+DRVLYS YP +YG IPR Sbjct: 36 HPWHDLEIGPGAPAVFNCVVEIPRGSKVKYELDKATGLIKVDRVLYSSVVYPHNYGFIPR 95 Query: 62 TWYDDDDPFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKDWKD 121 T +D DP D++V+M+E P + AR IGL MID G+KD K++AV +D ++ ++D Sbjct: 96 TLCEDGDPMDVLVLMQEQVVPGCFLRARAIGLMPMIDQGEKDDKIIAVCADDLEYRHFRD 155 Query: 122 IDDVPKAFLDEIAHFFKRYKELQGKEIIVEGWEGAEAAKREILRAIELY 170 I ++P L EI FF+ YK+ + KE+ V + AE A I +++LY Sbjct: 156 IKEIPLHRLQEIRRFFEDYKKNENKEVAVNEFLPAEDAINAIKYSMDLY 204 >gb|AAF26475.1|AC007323_16 (AC007323) T25K16.5 [Arabidopsis thaliana] Length = 230 Score = 162 bits (407), Expect = 2e-39 Identities = 82/189 (43%), Positives = 118/189 (62%), Gaps = 18/189 (9%) Query: 2 NPFHDLEPGPNVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPR 61 +P+HDLE GP P++ ++EI KGS+ KYELDKKTGL+K+DR+LYS YP +YG +PR Sbjct: 34 HPWHDLEIGPGAPQIFNVVVEITKGSKVKYELDKKTGLIKVDRILYSSVVYPHNYGFVPR 93 Query: 62 TWYDDDDPFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKDWKD 121 T +D+DP D++VIM+EP P + AR IGL MID G+KD K++AV V+DP +K + D Sbjct: 94 TLCEDNDPIDVLVIMQEPVLPGCFLRARAIGLMPMIDQGEKDDKIIAVCVDDPEYKHYTD 153 Query: 122 IDDVPKAFLDEIAHFFK------------------RYKELQGKEIIVEGWEGAEAAKREI 163 I ++P L EI FF+ K+ + KE+ V + +E+A I Sbjct: 154 IKELPPHRLSEIRRFFEDCILFLQCSSLFISIDLSTNKKNENKEVAVNDFLPSESAVEAI 213 Query: 164 LRAIELYKE 172 +++LY E Sbjct: 214 QYSMDLYAE 222 >gb|AAF27918.1|AF220202_1 (AF220202) soluble inorganic pyrophosphatase [Malus x domestica] Length = 228 Score = 159 bits (398), Expect = 2e-38 Identities = 78/171 (45%), Positives = 112/171 (64%) Query: 2 NPFHDLEPGPNVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPR 61 +P+HDLE GP P++ +IEIPKGS+ KYELDKKTGL+K DR+L S YP +YG IPR Sbjct: 50 HPWHDLEIGPGAPKIFNCVIEIPKGSKVKYELDKKTGLIKGDRILDSSVVYPHNYGFIPR 109 Query: 62 TWYDDDDPFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKDWKD 121 T +D+DP + IM+EP P + A+ IGL MID G+KD +++AV +DP ++ + D Sbjct: 110 TLCEDNDPLGCLDIMQEPVVPGCFLRAKAIGLMPMIDQGEKDDQIIAVCADDPEYRHYND 169 Query: 122 IDDVPKAFLDEIAHFFKRYKELQGKEIIVEGWEGAEAAKREILRAIELYKE 172 I ++P L EI FF+ YK+ + KE+ V+ + A A I ++ LY + Sbjct: 170 IKELPPHRLAEIRRFFEDYKKNENKEVAVDDFLPASTAFDAIQHSMNLYAD 220 >sp|P50308|IPYR_SULAC INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) >gi|1361933|pir||S57617 inorganic pyrophosphatase (EC 3.6.1.1) - Sulfolobus acidocaldarius >gi|2129434|pir||S65965 inorganic pyrophosphatase (EC 3.6.1.1) - Sulfolobus acidocaldarius >gi|4930102|pdb|1QEZ|F Chain F, Sulfolobus Acidocaldarius Inorganic Pyrophosphatase: An Archael Pyrophosphatase. >gi|4930098|pdb|1QEZ|B Chain B, Sulfolobus Acidocaldarius Inorganic Pyrophosphatase: An Archael Pyrophosphatase. >gi|4930100|pdb|1QEZ|D Chain D, Sulfolobus Acidocaldarius Inorganic Pyrophosphatase: An Archael Pyrophosphatase. >gi|4930101|pdb|1QEZ|E Chain E, Sulfolobus Acidocaldarius Inorganic Pyrophosphatase: An Archael Pyrophosphatase. >gi|4930099|pdb|1QEZ|C Chain C, Sulfolobus Acidocaldarius Inorganic Pyrophosphatase: An Archael Pyrophosphatase. >gi|4930097|pdb|1QEZ|A Chain A, Sulfolobus Acidocaldarius Inorganic Pyrophosphatase: An Archael Pyrophosphatase. >gi|886704|emb|CAA57434.1| (X81842) inorganic pyrophosphatase [Sulfolobus acidocaldarius] Length = 173 Score = 158 bits (395), Expect = 5e-38 Identities = 79/165 (47%), Positives = 109/165 (65%), Gaps = 3/165 (1%) Query: 7 LEPGPNVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDD 66 L PG N P+VV L+EIP+GS KYE D + G++K+DRVLY+ YP +YG IP T +D Sbjct: 3 LSPGKNAPDVVNVLVEIPQGSNIKYEYDDEEGVIKVDRVLYTSMNYPFNYGFIPGTLEED 62 Query: 67 DDPFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVE--DPYFKDWKDIDD 124 DP D++VI YP ++IE RPIG+ M D +D K++AVP + DP F + KDI+D Sbjct: 63 GDPLDVLVITNYQLYPGSVIEVRPIGILYMKDEEGEDAKIVAVPKDKTDPSFSNIKDIND 122 Query: 125 VPKAFLDEIAHFFKRYKELQ-GKEIIVEGWEGAEAAKREILRAIE 168 +P+A ++I HFF+ YKEL+ GK + + GW A AK I AI+ Sbjct: 123 LPQATKNKIVHFFEHYKELEPGKYVKISGWGSATEAKNRIQLAIK 167 >pir||S76172 inorganic pyrophosphatase (EC 3.6.1.1) slr1622 [similarity] - Synechocystis sp. (strain PCC 6803) >gi|1653518|dbj|BAA18431.1| (D90914) inorganic pyrophosphatase [Synechocystis sp.] Length = 233 Score = 156 bits (391), Expect = 1e-37 Identities = 81/168 (48%), Positives = 104/168 (61%), Gaps = 2/168 (1%) Query: 6 DLEPGPNVPE--VVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTW 63 DL P P+ ++ LIEIP GS+NKYE DK LDRVLYS YP DYG IP T Sbjct: 66 DLSRIPAQPKAGLINVLIEIPAGSKNKYEFDKDMNCFALDRVLYSSVQYPYDYGFIPNTL 125 Query: 64 YDDDDPFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKDWKDID 123 DD DP D MVIM +PT+P +I ARPIG+ +MID GD+D K+L VP +DP + K I+ Sbjct: 126 ADDGDPLDGMVIMDQPTFPGCVITARPIGMLEMIDGGDRDEKILCVPAKDPRYTYVKSIN 185 Query: 124 DVPKAFLDEIAHFFKRYKELQGKEIIVEGWEGAEAAKREILRAIELYK 171 D+ LDEIA FF+ YK L+ K + GW+ +A + ++ YK Sbjct: 186 DLAGHRLDEIAEFFRSYKNLEKKVTEILGWKDVDAVLPLVEECVKNYK 233 >sp|P80507|IPYR_SYNY3 INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) Length = 169 Score = 156 bits (391), Expect = 1e-37 Identities = 81/168 (48%), Positives = 104/168 (61%), Gaps = 2/168 (1%) Query: 6 DLEPGPNVPE--VVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTW 63 DL P P+ ++ LIEIP GS+NKYE DK LDRVLYS YP DYG IP T Sbjct: 2 DLSRIPAQPKAGLINVLIEIPAGSKNKYEFDKDMNCFALDRVLYSSVQYPYDYGFIPNTL 61 Query: 64 YDDDDPFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKDWKDID 123 DD DP D MVIM +PT+P +I ARPIG+ +MID GD+D K+L VP +DP + K I+ Sbjct: 62 ADDGDPLDGMVIMDQPTFPGCVITARPIGMLEMIDGGDRDEKILCVPAKDPRYTYVKSIN 121 Query: 124 DVPKAFLDEIAHFFKRYKELQGKEIIVEGWEGAEAAKREILRAIELYK 171 D+ LDEIA FF+ YK L+ K + GW+ +A + ++ YK Sbjct: 122 DLAGHRLDEIAEFFRSYKNLEKKVTEILGWKDVDAVLPLVEECVKNYK 169 >sp|O23979|IPYR_HORVD SOLUBLE INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) >gi|7436037|pir||T04421 probable inorganic pyrophosphatase (EC 3.6.1.1), soluble - two-rowed barley >gi|2258074|gb|AAC50012.1| (AF009675) soluble inorganic pyrophosphatase [Hordeum vulgare var. distichum] Length = 215 Score = 154 bits (385), Expect = 7e-37 Identities = 78/172 (45%), Positives = 115/172 (66%), Gaps = 4/172 (2%) Query: 2 NPFHDLEPGPNVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPR 61 +P+HDLE GP P V ++EI KGS+ KYELDKKTGL+K+DRVLYS YP +YG IPR Sbjct: 39 HPWHDLEIGPGAPAVFNVVVEITKGSKVKYELDKKTGLIKVDRVLYSSVVYPHNYGFIPR 98 Query: 62 TWYDDDDPFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKDWK- 120 T +D+DP D++V+M+EP P + + AR IGL MID G+KD K++AV +DP ++ + Sbjct: 99 TLCEDNDPMDVLVLMQEPVIPGSFLRARAIGLMPMIDQGEKDDKIIAVCADDPEYRHYST 158 Query: 121 DIDDVPKAFLDEIAHFFKRYKELQGKEIIVEGWEGAEAAKREILRAIELYKE 172 + +P+ L EI + YK+ + KE+ V+ + A A+ I +++LY + Sbjct: 159 SVSLLPR--LQEIKR-LEDYKKNENKEVAVDAFLPATTAREAIQYSMDLYAQ 207 >pir||H72550 probable inorganic pyrophosphatase APE1692 - Aeropyrum pernix (strain K1) >gi|5105380|dbj|BAA80693.1| (AP000062) 207aa long hypothetical inorganic pyrophosphatase [Aeropyrum pernix] Length = 207 Score = 153 bits (382), Expect = 2e-36 Identities = 80/166 (48%), Positives = 103/166 (61%), Gaps = 3/166 (1%) Query: 9 PGPNVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDDDD 68 PG P+VV +IEIP S KYE DK+ ++K+DR LY+ YP +YG IP T +D D Sbjct: 40 PGDEAPDVVNVVIEIPMNSSVKYEFDKEACIVKVDRFLYTSMVYPFNYGFIPGTLEEDGD 99 Query: 69 PFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVE--DPYFKDWKDIDDVP 126 P D++VI REP P ++IEA P+ + M D D KV+AVP DP F +KD+ D+P Sbjct: 100 PVDVLVISREPVAPGSLIEAVPVAVLDMEDEEGPDSKVVAVPKAKLDPLFASYKDVGDIP 159 Query: 127 KAFLDEIAHFFKRYKELQ-GKEIIVEGWEGAEAAKREILRAIELYK 171 A +I HFF+ YKEL+ GK + V GW A AK I RAIE YK Sbjct: 160 DALKSKIKHFFEHYKELEPGKWVRVTGWRPAADAKEIIRRAIERYK 205 >sp|Q9YBA5|IPYR_AERPE INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) Length = 176 Score = 153 bits (382), Expect = 2e-36 Identities = 80/166 (48%), Positives = 103/166 (61%), Gaps = 3/166 (1%) Query: 9 PGPNVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDDDD 68 PG P+VV +IEIP S KYE DK+ ++K+DR LY+ YP +YG IP T +D D Sbjct: 9 PGDEAPDVVNVVIEIPMNSSVKYEFDKEACIVKVDRFLYTSMVYPFNYGFIPGTLEEDGD 68 Query: 69 PFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVE--DPYFKDWKDIDDVP 126 P D++VI REP P ++IEA P+ + M D D KV+AVP DP F +KD+ D+P Sbjct: 69 PVDVLVISREPVAPGSLIEAVPVAVLDMEDEEGPDSKVVAVPKAKLDPLFASYKDVGDIP 128 Query: 127 KAFLDEIAHFFKRYKELQ-GKEIIVEGWEGAEAAKREILRAIELYK 171 A +I HFF+ YKEL+ GK + V GW A AK I RAIE YK Sbjct: 129 DALKSKIKHFFEHYKELEPGKWVRVTGWRPAADAKEIIRRAIERYK 174 >pir||JE0392 inorganic pyrophosphatase (EC 3.6.1.1) - Sulfolobus sp. (strain 7) Length = 172 Score = 152 bits (380), Expect = 3e-36 Identities = 79/170 (46%), Positives = 105/170 (61%), Gaps = 3/170 (1%) Query: 7 LEPGPNVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDD 66 L PG P+ V LIEIP GS KYE D++ ++K+DR+LY+ YP +YG IP T +D Sbjct: 3 LSPGKKAPDEVNVLIEIPLGSNIKYEYDEEEEVVKVDRILYTSMVYPFNYGFIPGTLEED 62 Query: 67 DDPFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVE--DPYFKDWKDIDD 124 DP D++VI P P T IE RPIG+ M D +D K++AVP + DP F + KDI D Sbjct: 63 GDPLDVLVISNYPLLPGTAIEVRPIGILYMRDEEGEDAKIIAVPKDKVDPTFSNIKDIID 122 Query: 125 VPKAFLDEIAHFFKRYKELQ-GKEIIVEGWEGAEAAKREILRAIELYKEK 173 +P+A D+I HFF+ YKEL+ GK + + GW G AK I AI+ K Sbjct: 123 LPQAIKDKINHFFEHYKELEPGKWVKISGWGGVSEAKTRINEAIKRANSK 172 >sp|O69540|IPYR_MYCLE INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) >gi|3097233|emb|CAA18808.1| (AL023093) inorganic pyrophosphatase [Mycobacterium leprae] Length = 162 Score = 152 bits (379), Expect = 4e-36 Identities = 74/152 (48%), Positives = 99/152 (64%), Gaps = 1/152 (0%) Query: 21 IEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDDDDPFDIMVIMREPT 80 IEIPKG RNKYE+D KTG ++LDR LY+P YP DYG I T +D DP D +V++ EP Sbjct: 7 IEIPKGQRNKYEVDHKTGRVRLDRYLYTPMAYPTDYGFIEDTLGEDGDPLDALVLLPEPL 66 Query: 81 YPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKDWKDIDDVPKAFLDEIAHFFKRY 140 +P ++EARP+G+F+M+D D KVL VPV D + I DVP LD I HFF Y Sbjct: 67 FPGVLVEARPVGMFRMVDEHGGDDKVLCVPVNDHRWDHIHGIIDVPTFELDAIKHFFVHY 126 Query: 141 KELQ-GKEIIVEGWEGAEAAKREILRAIELYK 171 K+L+ GK + W G + A+ E+ R++E +K Sbjct: 127 KDLEPGKFVKAADWVGRDEAEAEVQRSVERFK 158 >sp|O06379|IPYR_MYCTU INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) >gi|7436018|pir||E70561 probable inorganic pyrophosphatase - Mycobacterium tuberculosis (strain H37RV) >gi|2105066|emb|CAB08851.1| (Z95436) ppa [Mycobacterium tuberculosis] Length = 162 Score = 150 bits (375), Expect = 1e-35 Identities = 72/152 (47%), Positives = 98/152 (64%), Gaps = 1/152 (0%) Query: 21 IEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDDDDPFDIMVIMREPT 80 IEIPKG RNKYE+D +TG ++LDR LY+P YP DYG I T DD DP D +V++ +P Sbjct: 7 IEIPKGQRNKYEVDHETGRVRLDRYLYTPMAYPTDYGFIEDTLGDDGDPLDALVLLPQPV 66 Query: 81 YPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKDWKDIDDVPKAFLDEIAHFFKRY 140 +P ++ ARP+G+F+M+D D KVL VP DP + +DI DVP LD I HFF Y Sbjct: 67 FPGVLVAARPVGMFRMVDEHGGDDKVLCVPAGDPRWDHVQDIGDVPAFELDAIKHFFVHY 126 Query: 141 KELQ-GKEIIVEGWEGAEAAKREILRAIELYK 171 K+L+ GK + W A+ E+ R++E +K Sbjct: 127 KDLEPGKFVKAADWVDRAEAEAEVQRSVERFK 158 >gb|AAG31654.1| (AF315738) PRLI-interacting factor F [Arabidopsis thaliana] Length = 166 Score = 150 bits (374), Expect = 1e-35 Identities = 74/153 (48%), Positives = 104/153 (67%) Query: 20 LIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDDDDPFDIMVIMREP 79 +IEI KGS+ KYELDKKTGL+K+DR+LYS YP +YG +PRT +D+DP D++VIM+EP Sbjct: 6 VIEISKGSKVKYELDKKTGLIKVDRILYSSVVYPHNYGFVPRTLCEDNDPIDVLVIMQEP 65 Query: 80 TYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKDWKDIDDVPKAFLDEIAHFFKR 139 P + AR IGL MID G+KD K++AV V+DP +K +I+++P L EI FF+ Sbjct: 66 VLPGCFLRARAIGLMPMIDQGEKDDKIIAVCVDDPEYKHITNINELPPHRLSEIRRFFED 125 Query: 140 YKELQGKEIIVEGWEGAEAAKREILRAIELYKE 172 YK+ + KE+ V + A I +++LY E Sbjct: 126 YKKNENKEVAVNDFLQPGPAIEAIQYSMDLYAE 158 >gb|AAK42538.1| Inorganic pyrophosphatase, putative (ppa) [Sulfolobus solfataricus] Length = 172 Score = 146 bits (364), Expect = 2e-34 Identities = 74/169 (43%), Positives = 103/169 (60%), Gaps = 3/169 (1%) Query: 7 LEPGPNVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDD 66 L PG P+ + IEIP GS KYE D++ ++K+DRVLY+ YP +YG IP T +D Sbjct: 3 LGPGKKAPDEINVFIEIPMGSNIKYEYDEEEDIIKVDRVLYTSMVYPFNYGFIPETLEED 62 Query: 67 DDPFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVP--VEDPYFKDWKDIDD 124 DP D++V+ P T+IEARPIG+ M D +D KV+AVP DP F + D+ D Sbjct: 63 GDPLDVLVLGNYSLMPGTVIEARPIGMIYMRDEEGEDAKVIAVPRNKTDPSFSNINDVKD 122 Query: 125 VPKAFLDEIAHFFKRYKELQ-GKEIIVEGWEGAEAAKREILRAIELYKE 172 +P+A ++I HFF+ YKEL+ K + + GW AK I +AIE K+ Sbjct: 123 LPEAIRNKIVHFFEHYKELEPNKWVKISGWGSVAEAKERIKKAIERKKQ 171 >pir||C83141 inorganic pyrophosphatase PA4031 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9950226|gb|AAG07418.1|AE004820_3 (AE004820) inorganic pyrophosphatase [Pseudomonas aeruginosa] Length = 175 Score = 141 bits (352), Expect = 5e-33 Identities = 70/173 (40%), Positives = 106/173 (60%), Gaps = 4/173 (2%) Query: 4 FHDLEPGPNVPEVVYALIEIPKGSRN-KYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRT 62 + + G ++P +Y IEIP KYE+DK T L +DR + +P FYP +YG IP T Sbjct: 3 YSKIPAGKDLPNDIYVAIEIPANHAPIKYEIDKDTDCLFVDRFMATPMFYPANYGFIPNT 62 Query: 63 WYDDDDPFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVE--DPYFKDWK 120 DD DP D++V+ P P ++I ARP+G+ M D D K++AVP + +KD K Sbjct: 63 LADDGDPLDVLVVTPYPVAPGSVIRARPVGVLHMTDEAGGDAKLIAVPHDKLSVLYKDVK 122 Query: 121 DIDDVPKAFLDEIAHFFKRYKELQ-GKEIIVEGWEGAEAAKREILRAIELYKE 172 + D+P L++I HFF+ YK+L+ GK + VEGW A+AA+ EI +A+ +++ Sbjct: 123 EYTDLPALLLEQIKHFFENYKDLEKGKWVKVEGWGNADAARAEITKAVAAFQK 175 >sp|O22537|IPYR_ORYSA SOLUBLE INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) >gi|7436035|pir||T02082 probable inorganic pyrophosphatase (EC 3.6.1.1) - rice >gi|2570501|gb|AAB82136.1| (AF022733) inorganic pyrophosphatase [Oryza sativa] Length = 214 Score = 140 bits (349), Expect = 1e-32 Identities = 74/169 (43%), Positives = 101/169 (58%) Query: 2 NPFHDLEPGPNVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPR 61 +P+HDLE GP P V ++EIP+GS+ K ELDK TGL+K+DRVLYS YP +YG IPR Sbjct: 36 HPWHDLEIGPGAPAVFNCVVEIPRGSKVKCELDKATGLIKVDRVLYSSVVYPHNYGFIPR 95 Query: 62 TWYDDDDPFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKDWKD 121 T +D DP D++V+M+E P + AR IGL MID G+KD K++AV +D Sbjct: 96 TLCEDGDPMDVLVLMQEQVVPGCFLRARAIGLMPMIDQGEKDDKIIAVRADDLNTATSGT 155 Query: 122 IDDVPKAFLDEIAHFFKRYKELQGKEIIVEGWEGAEAAKREILRAIELY 170 P A FF+ YK+ + KE+ V + AE A I +++ Y Sbjct: 156 SRKSPFTAFKRSAVFFEDYKKNENKEVAVNEFFPAEDAINAIKYSMDFY 204 >pdb|2PRD| Mol_id: 1; Molecule: Pyrophosphate Phosphohydrolase; Chain: Null; Ec: 3.6.1.1 Length = 174 Score = 139 bits (346), Expect = 3e-32 Identities = 75/168 (44%), Positives = 94/168 (55%), Gaps = 3/168 (1%) Query: 7 LEPGPNVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDD 66 L G PEVV+ +IE+P+GS NKYE D G +KLDRVL FYP DYG IP T +D Sbjct: 6 LPVGDKAPEVVHMVIEVPRGSGNKYEYDPDLGAIKLDRVLPGAQFYPGDYGFIPSTLAED 65 Query: 67 DDPFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKDWKDIDDVP 126 DP D +V+ P P ++E R +GL M D D KV+ V ED +DI DVP Sbjct: 66 GDPLDGLVLSTYPLLPGVVVEVRVVGLLLMEDEKGGDAKVIGVVAEDQRLDHIQDIGDVP 125 Query: 127 KAFLDEIAHFFKRYKELQ---GKEIIVEGWEGAEAAKREILRAIELYK 171 + EI HFF+ YK L+ GK + V GW +AA E+ I YK Sbjct: 126 EGVKQEIQHFFETYKALEAKKGKWVKVTGWRDRKAALEEVRACIARYK 173 >sp|P38576|IPYR_THETH INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) >gi|7436017|pir||JE0189 inorganic pyrophosphatase (EC 3.6.1.1) - Thermus aquaticus >gi|2810983|dbj|BAA24521.1| (AB010580) Tth PPase [Thermus thermophilus] Length = 175 Score = 139 bits (346), Expect = 3e-32 Identities = 75/168 (44%), Positives = 94/168 (55%), Gaps = 3/168 (1%) Query: 7 LEPGPNVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDD 66 L G PEVV+ +IE+P+GS NKYE D G +KLDRVL FYP DYG IP T +D Sbjct: 7 LPVGDKAPEVVHMVIEVPRGSGNKYEYDPDLGAIKLDRVLPGAQFYPGDYGFIPSTLAED 66 Query: 67 DDPFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKDWKDIDDVP 126 DP D +V+ P P ++E R +GL M D D KV+ V ED +DI DVP Sbjct: 67 GDPLDGLVLSTYPLLPGVVVEVRVVGLLLMEDEKGGDAKVIGVVAEDQRLDHIQDIGDVP 126 Query: 127 KAFLDEIAHFFKRYKELQ---GKEIIVEGWEGAEAAKREILRAIELYK 171 + EI HFF+ YK L+ GK + V GW +AA E+ I YK Sbjct: 127 EGVKQEIQHFFETYKALEAKKGKWVKVTGWRDRKAALEEVRACIARYK 174 >sp|Q9X8I9|IPYR_STRCO INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) >gi|7480775|pir||T36335 probable inorganic pyrophosphatase - Streptomyces coelicolor >gi|4808348|emb|CAB42762.1| (AL049841) putative inorganic pyrophosphatase [Streptomyces coelicolor A3(2)] Length = 163 Score = 136 bits (339), Expect = 2e-31 Identities = 70/156 (44%), Positives = 98/156 (61%), Gaps = 1/156 (0%) Query: 21 IEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDDDDPFDIMVIMREPT 80 IEIPKGSRNKYE+D +TG ++LDR L++ YP DYG + T +D DP D +VI+ EPT Sbjct: 7 IEIPKGSRNKYEVDHETGRIRLDRRLFTSTAYPTDYGFVENTLGEDGDPLDALVILDEPT 66 Query: 81 YPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKDWKDIDDVPKAFLDEIAHFFKRY 140 +P +I R IG+F+M D D K+L VP DP + +DI V + EI HFF+ Y Sbjct: 67 FPGCLIRCRAIGMFRMTDEAGGDDKLLCVPSTDPRVEHLRDIHHVSEFDRLEIQHFFEVY 126 Query: 141 KELQ-GKEIIVEGWEGAEAAKREILRAIELYKEKFG 175 K+L+ GK + W G A+ EI R+ + +K++ G Sbjct: 127 KDLEPGKSVEGADWVGRTEAEAEIERSYKRFKDQGG 162 >pir||H82589 inorganic pyrophosphatase XF2171 [imported] - Xylella fastidiosa (strain 9a5c) >gi|9107311|gb|AAF84970.1|AE004031_2 (AE004031) inorganic pyrophosphatase [Xylella fastidiosa] Length = 178 Score = 136 bits (339), Expect = 2e-31 Identities = 67/167 (40%), Positives = 105/167 (62%), Gaps = 4/167 (2%) Query: 10 GPNVPEVVYALIEIPKGSRN-KYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDDDD 68 G N+PE + +IEIPK S KYE+DK +G + +DR+L +P YP +YG +P T D D Sbjct: 9 GNNLPEEINVIIEIPKDSEPVKYEVDKASGAIFVDRILSTPMRYPCNYGYVPNTLCGDGD 68 Query: 69 PFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPY--FKDWKDIDDVP 126 P D+MV++ P P +++ RP+G+ +M D D K+LAVPV + + +DI+ V Sbjct: 69 PVDVMVVLPLPLVPGSVVRCRPVGVLQMKDEAGNDEKLLAVPVSKIFSGYSHIEDINQVS 128 Query: 127 KAFLDEIAHFFKRYKELQ-GKEIIVEGWEGAEAAKREILRAIELYKE 172 +L+ I HFF+ YK+L+ GK + ++GW A AK+ + A++ YK+ Sbjct: 129 AHWLERIGHFFEHYKDLEKGKWVEIDGWGNATTAKQILTNAVQRYKD 175 >sp|P17288|IPYR_ECOLI INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) >gi|67793|pir||PWEC inorganic pyrophosphatase (EC 3.6.1.1) - Escherichia coli >gi|450373|gb|AAB88583.1| (M23550) inorganic pyrophosphatase [Escherichia coli] >gi|537068|gb|AAA97123.1| (U14003) ppa gene product [Escherichia coli] >gi|1790673|gb|AAC77183.1| (AE000494) inorganic pyrophosphatase [Escherichia coli K12] Length = 176 Score = 136 bits (338), Expect = 2e-31 Identities = 72/168 (42%), Positives = 105/168 (61%), Gaps = 4/168 (2%) Query: 10 GPNVPEVVYALIEIPKGSRN-KYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDDDD 68 G ++PE +Y +IEIP + KYE+DK++G L +DR + + FYP +YG I T D D Sbjct: 9 GKDLPEDIYVVIEIPANADPIKYEIDKESGALFVDRFMSTAMFYPCNYGYINHTLSLDGD 68 Query: 69 PFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVE--DPYFKDWKDIDDVP 126 P D++V P P ++I RP+G+ KM D +D K++AVP + KD++D+P Sbjct: 69 PVDVLVPTPYPLQPGSVIRCRPVGVLKMTDEAGEDAKLVAVPHSKLSKEYDHIKDVNDLP 128 Query: 127 KAFLDEIAHFFKRYKELQ-GKEIIVEGWEGAEAAKREILRAIELYKEK 173 + +IAHFF+ YK+L+ GK + VEGWE AEAAK EI+ + E K K Sbjct: 129 ELLKAQIAHFFEHYKDLEKGKWVKVEGWENAEAAKAEIVASFERAKNK 176 >pdb|1JFD|A Chain A, Structure Of Inorganic Pyrophosphatase >gi|2781228|pdb|1JFD|B Chain B, Structure Of Inorganic Pyrophosphatase >gi|1421110|pdb|1INO| Recombinant Inorganic Pyrophosphatase From Escherichia Coli >gi|1943415|pdb|2EIP|B Chain B, Inorganic Pyrophosphatase >gi|2392377|pdb|1IPW|B Chain B, Inorganic Pyrophosphatase From Escherichia Coli With Three Magnesium Ions >gi|1943562|pdb|1FAJ| Inorganic Pyrophosphatase >gi|1943414|pdb|2EIP|A Chain A, Inorganic Pyrophosphatase >gi|2392376|pdb|1IPW|A Chain A, Inorganic Pyrophosphatase From Escherichia Coli With Three Magnesium Ions Length = 175 Score = 136 bits (338), Expect = 2e-31 Identities = 72/168 (42%), Positives = 105/168 (61%), Gaps = 4/168 (2%) Query: 10 GPNVPEVVYALIEIPKGSRN-KYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDDDD 68 G ++PE +Y +IEIP + KYE+DK++G L +DR + + FYP +YG I T D D Sbjct: 8 GKDLPEDIYVVIEIPANADPIKYEIDKESGALFVDRFMSTAMFYPCNYGYINHTLSLDGD 67 Query: 69 PFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVE--DPYFKDWKDIDDVP 126 P D++V P P ++I RP+G+ KM D +D K++AVP + KD++D+P Sbjct: 68 PVDVLVPTPYPLQPGSVIRCRPVGVLKMTDEAGEDAKLVAVPHSKLSKEYDHIKDVNDLP 127 Query: 127 KAFLDEIAHFFKRYKELQ-GKEIIVEGWEGAEAAKREILRAIELYKEK 173 + +IAHFF+ YK+L+ GK + VEGWE AEAAK EI+ + E K K Sbjct: 128 ELLKAQIAHFFEHYKDLEKGKWVKVEGWENAEAAKAEIVASFERAKNK 175 >pdb|1OBW|A Chain A, Structure Of Inorganic Pyrophosphatase >gi|2554847|pdb|1OBW|B Chain B, Structure Of Inorganic Pyrophosphatase >gi|2554848|pdb|1OBW|C Chain C, Structure Of Inorganic Pyrophosphatase >gi|809170|pdb|1IGP| Inorganic Pyrophosphatase (E.C.3.6.1.1) Length = 175 Score = 134 bits (333), Expect = 9e-31 Identities = 71/168 (42%), Positives = 104/168 (61%), Gaps = 4/168 (2%) Query: 10 GPNVPEVVYALIEIPKGSRN-KYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDDDD 68 G ++PE +Y +IEIP + KYE+DK++G L +DR + + FYP +YG I T D D Sbjct: 8 GKDLPEDIYVVIEIPANADPIKYEIDKESGALFVDRFMSTAMFYPCNYGYINHTLSLDGD 67 Query: 69 PFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVE--DPYFKDWKDIDDVP 126 P D++V P P ++ RP+G+ KM D +D K++AVP + KD++D+P Sbjct: 68 PVDVLVPTPYPLQPGSVTRCRPVGVLKMTDEAGEDAKLVAVPHSKLSKEYDHIKDVNDLP 127 Query: 127 KAFLDEIAHFFKRYKELQ-GKEIIVEGWEGAEAAKREILRAIELYKEK 173 + +IAHFF+ YK+L+ GK + VEGWE AEAAK EI+ + E K K Sbjct: 128 ELLKAQIAHFFEHYKDLEKGKWVKVEGWENAEAAKAEIVASFERAKNK 175 >pdb|1MJW|A Chain A, Structure Of Inorganic Pyrophosphatase Mutant D42n >gi|2781251|pdb|1MJW|B Chain B, Structure Of Inorganic Pyrophosphatase Mutant D42n Length = 175 Score = 134 bits (333), Expect = 9e-31 Identities = 71/168 (42%), Positives = 105/168 (62%), Gaps = 4/168 (2%) Query: 10 GPNVPEVVYALIEIPKGSRN-KYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDDDD 68 G ++PE +Y +IEIP + KYE+DK++G L ++R + + FYP +YG I T D D Sbjct: 8 GKDLPEDIYVVIEIPANADPIKYEIDKESGALFVNRFMSTAMFYPCNYGYINHTLSLDGD 67 Query: 69 PFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVE--DPYFKDWKDIDDVP 126 P D++V P P ++I RP+G+ KM D +D K++AVP + KD++D+P Sbjct: 68 PVDVLVPTPYPLQPGSVIRCRPVGVLKMTDEAGEDAKLVAVPHSKLSKEYDHIKDVNDLP 127 Query: 127 KAFLDEIAHFFKRYKELQ-GKEIIVEGWEGAEAAKREILRAIELYKEK 173 + +IAHFF+ YK+L+ GK + VEGWE AEAAK EI+ + E K K Sbjct: 128 ELLKAQIAHFFEHYKDLEKGKWVKVEGWENAEAAKAEIVASFERAKNK 175 >pdb|1MJX|A Chain A, Structure Of Inorganic Pyrophosphatase Mutant D65n >gi|2781253|pdb|1MJX|B Chain B, Structure Of Inorganic Pyrophosphatase Mutant D65n Length = 175 Score = 134 bits (333), Expect = 9e-31 Identities = 71/168 (42%), Positives = 105/168 (62%), Gaps = 4/168 (2%) Query: 10 GPNVPEVVYALIEIPKGSRN-KYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDDDD 68 G ++PE +Y +IEIP + KYE+DK++G L +DR + + FYP +YG I T + D Sbjct: 8 GKDLPEDIYVVIEIPANADPIKYEIDKESGALFVDRFMSTAMFYPCNYGYINHTLSLNGD 67 Query: 69 PFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVE--DPYFKDWKDIDDVP 126 P D++V P P ++I RP+G+ KM D +D K++AVP + KD++D+P Sbjct: 68 PVDVLVPTPYPLQPGSVIRCRPVGVLKMTDEAGEDAKLVAVPHSKLSKEYDHIKDVNDLP 127 Query: 127 KAFLDEIAHFFKRYKELQ-GKEIIVEGWEGAEAAKREILRAIELYKEK 173 + +IAHFF+ YK+L+ GK + VEGWE AEAAK EI+ + E K K Sbjct: 128 ELLKAQIAHFFEHYKDLEKGKWVKVEGWENAEAAKAEIVASFERAKNK 175 >pdb|1MJZ| Structure Of Inorganic Pyrophosphatase Mutant D97n Length = 175 Score = 134 bits (333), Expect = 9e-31 Identities = 71/168 (42%), Positives = 105/168 (62%), Gaps = 4/168 (2%) Query: 10 GPNVPEVVYALIEIPKGSRN-KYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDDDD 68 G ++PE +Y +IEIP + KYE+DK++G L +DR + + FYP +YG I T D D Sbjct: 8 GKDLPEDIYVVIEIPANADPIKYEIDKESGALFVDRFMSTAMFYPCNYGYINHTLSLDGD 67 Query: 69 PFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVE--DPYFKDWKDIDDVP 126 P D++V P P ++I RP+G+ KM + +D K++AVP + KD++D+P Sbjct: 68 PVDVLVPTPYPLQPGSVIRCRPVGVLKMTNEAGEDAKLVAVPHSKLSKEYDHIKDVNDLP 127 Query: 127 KAFLDEIAHFFKRYKELQ-GKEIIVEGWEGAEAAKREILRAIELYKEK 173 + +IAHFF+ YK+L+ GK + VEGWE AEAAK EI+ + E K K Sbjct: 128 ELLKAQIAHFFEHYKDLEKGKWVKVEGWENAEAAKAEIVASFERAKNK 175 >sp|O34955|IPYR_LEGPN INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) >gi|2613038|gb|AAB84257.1| (AF030232) inorganic pyrophosphatase [Legionella pneumophila] >gi|2642277|gb|AAC02428.1| (AF031464) inorganic pyrophosphatase [Legionella pneumophila] Length = 178 Score = 132 bits (330), Expect = 2e-30 Identities = 71/169 (42%), Positives = 98/169 (57%), Gaps = 4/169 (2%) Query: 6 DLEPGPNVPEVVYALIEIPK-GSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWY 64 ++ G +VP V +IEIP G KYE+DKKTG L +DR + + FYP +YG IP T Sbjct: 5 EIPSGRDVPNEVNVIIEIPMHGEPVKYEVDKKTGALFVDRFMTTAMFYPTNYGYIPNTLS 64 Query: 65 DDDDPFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVE--DPYFKDWKDI 122 +D DP D++VI P +I R +G+ KM D D K+LAVP ++ + Sbjct: 65 EDGDPVDVLVITPVPLISGAVISCRAVGMLKMTDESGVDAKILAVPTTKLSKMYQSMQTY 124 Query: 123 DDVPKAFLDEIAHFFKRYKEL-QGKEIIVEGWEGAEAAKREILRAIELY 170 D+P+ L I HFFK YK+L +GK + VEGW G +AA+ EI +I Y Sbjct: 125 QDIPQHLLLSIEHFFKHYKDLEEGKWVKVEGWVGPDAAREEITSSINRY 173 >pdb|1MJY|A Chain A, Structure Of Inorganic Pyrophosphatase Mutant D70n >gi|2781255|pdb|1MJY|B Chain B, Structure Of Inorganic Pyrophosphatase Mutant D70n Length = 175 Score = 132 bits (328), Expect = 3e-30 Identities = 70/168 (41%), Positives = 104/168 (61%), Gaps = 4/168 (2%) Query: 10 GPNVPEVVYALIEIPKGSRN-KYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDDDD 68 G ++PE +Y +IEIP + KYE+DK++G L +DR + + FYP +YG I T D D Sbjct: 8 GKDLPEDIYVVIEIPANADPIKYEIDKESGALFVDRFMSTAMFYPCNYGYINHTLSLDGD 67 Query: 69 PFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVE--DPYFKDWKDIDDVP 126 P +++V P P ++ RP+G+ KM D +D K++AVP + KD++D+P Sbjct: 68 PVNVLVPTPYPLQPGSVTRCRPVGVLKMTDEAGEDAKLVAVPHSKLSKEYDHIKDVNDLP 127 Query: 127 KAFLDEIAHFFKRYKELQ-GKEIIVEGWEGAEAAKREILRAIELYKEK 173 + +IAHFF+ YK+L+ GK + VEGWE AEAAK EI+ + E K K Sbjct: 128 ELLKAQIAHFFEHYKDLEKGKWVKVEGWENAEAAKAEIVASFERAKNK 175 >sp|O05545|IPYR_GLUSU INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) Length = 176 Score = 130 bits (324), Expect = 1e-29 Identities = 67/168 (39%), Positives = 98/168 (57%), Gaps = 3/168 (1%) Query: 7 LEPGPNVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDD 66 + PG ++P + +IEIP+GS+ KYE+DK +G L +DR L++P YP YG IP T D Sbjct: 9 ISPGKDLPNDINVVIEIPQGSQVKYEVDKDSGALVVDRFLFTPHAYPAAYGFIPGTLGRD 68 Query: 67 DDPFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVE--DPYFKDWKDIDD 124 DP D +V+ P ++I ARPIG+ KM D +D K++ VP P F + +DD Sbjct: 69 GDPADALVLTPAAVVPGSVIRARPIGMLKMEDESGQDEKIICVPARKVHPQFSNVHSVDD 128 Query: 125 VPKAFLDEIAHFFKRYKELQ-GKEIIVEGWEGAEAAKREILRAIELYK 171 +P+ I HFF+RYK+L+ K + V GW A + I+ A+ K Sbjct: 129 LPEITKKAITHFFERYKDLEPNKWVKVTGWADKAEAGKVIMEALAAAK 176 >pir||C82064 inorganic pyrophosphatase VC2545 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9657129|gb|AAF95686.1| (AE004323) inorganic pyrophosphatase [Vibrio cholerae] Length = 176 Score = 129 bits (321), Expect = 2e-29 Identities = 67/173 (38%), Positives = 107/173 (61%), Gaps = 4/173 (2%) Query: 5 HDLEPGPNVPEVVYALIEIPKGSRN-KYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTW 63 +++ G ++P+ +Y +IEIP + KYE+DK++G + +DR + +P FYP +YG + T Sbjct: 4 NNVPAGKSLPDDIYVVIEIPANADPIKYEVDKESGAVFVDRFMSAPMFYPCNYGYVNHTL 63 Query: 64 YDDDDPFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVE--DPYFKDWKD 121 D DP D++V P P ++I RP+G+ KM D +D KV+AVP + +D Sbjct: 64 SLDGDPVDVLVPTPYPLIPGSVIRCRPVGVLKMTDESGEDAKVVAVPHTKISKEYDHIQD 123 Query: 122 IDDVPKAFLDEIAHFFKRYKELQ-GKEIIVEGWEGAEAAKREILRAIELYKEK 173 ++D+P +I HFF+RYKEL+ GK + V+GWE A +A+ EIL + E + K Sbjct: 124 VNDLPALLKAQITHFFERYKELESGKWVKVDGWEDAASARAEILSSYERAQNK 176 >sp|P51064|IPYR_BARBA INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) >gi|940255|gb|AAB88054.1| (L46591) inorganic pyrophosphatase [Bartonella bacilliformis] Length = 177 Score = 120 bits (299), Expect = 8e-27 Identities = 69/166 (41%), Positives = 93/166 (55%), Gaps = 4/166 (2%) Query: 10 GPNVPEVVYALIEIPKGSRN-KYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDDDD 68 G N PE V +IE+P S+ KYE+DKK+G L +DR + + YP +YG IP T +D D Sbjct: 9 GNNPPEDVNVIIEVPVDSQPVKYEMDKKSGSLFVDRFISTSMVYPGNYGFIPHTLSEDSD 68 Query: 69 PFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVE--DPYFKDWKDIDDVP 126 P D++V P P +I RPIG M D G KD K++AVP + D D+ Sbjct: 69 PIDVLVCNTRPLIPGCVINVRPIGALIMEDDGGKDEKIIAVPTPKLTQQYIGIHDYTDLT 128 Query: 127 KAFLDEIAHFFKRYKELQ-GKEIIVEGWEGAEAAKREILRAIELYK 171 + L +I HFFK YK+L+ GK +EGW A+ I +AIE K Sbjct: 129 ENILKKIEHFFKHYKDLEAGKWAKIEGWRDKNFARELIQQAIERAK 174 >sp|Q9ZLL5|IPYR_HELPJ INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) >gi|7436026|pir||G71916 inorganic pyrophosphatase - Helicobacter pylori (strain J99) >gi|4155114|gb|AAD06146.1| (AE001489) inorganic pyrophosphatase [Helicobacter pylori J99] Length = 173 Score = 120 bits (297), Expect = 1e-26 Identities = 65/155 (41%), Positives = 97/155 (61%), Gaps = 3/155 (1%) Query: 20 LIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDDDDPFDIMVIMREP 79 +IEI K S KYELDK++G L +DRVLY YP +YG +P T D DP D +V+ Sbjct: 18 VIEISKHSNIKYELDKESGALMVDRVLYGAQNYPANYGFVPNTLGSDGDPVDALVLSDVA 77 Query: 80 TYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVE--DPYFKDWKDIDDVPKAFLDEIAHFF 137 ++++AR +G+ M D D K+LA+P++ DP KDIDD+ K LD+I HFF Sbjct: 78 FQAGSVVKARLVGVLNMEDESGMDEKLLALPIDKIDPTHSYVKDIDDLSKHTLDKIKHFF 137 Query: 138 KRYKELQ-GKEIIVEGWEGAEAAKREILRAIELYK 171 + YK+L+ K + V+G+E E+A + + +AI+ Y+ Sbjct: 138 ETYKDLEPNKWVKVKGFENKESAIKVLEKAIKAYQ 172 >sp|P56153|IPYR_HELPY INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) >gi|7436027|pir||D64597 inorganic pyrophosphatase - Helicobacter pylori (strain 26695) >gi|2313741|gb|AAD07684.1| (AE000576) inorganic pyrophosphatase (ppa) [Helicobacter pylori 26695] Length = 173 Score = 119 bits (295), Expect = 2e-26 Identities = 64/155 (41%), Positives = 97/155 (62%), Gaps = 3/155 (1%) Query: 20 LIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDDDDPFDIMVIMREP 79 +IEI K S KYELDK++G L +DRVLY YP +YG +P T D DP D +V+ Sbjct: 18 VIEISKHSNIKYELDKESGALMVDRVLYGAQNYPANYGFVPNTLGSDGDPVDALVLSDVA 77 Query: 80 TYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVE--DPYFKDWKDIDDVPKAFLDEIAHFF 137 ++++AR +G+ M D D K++A+P++ DP KDIDD+ K LD+I HFF Sbjct: 78 FQAGSVVKARLVGVLNMEDESGMDEKLIALPIDKIDPTHSYVKDIDDLSKHTLDKIKHFF 137 Query: 138 KRYKELQ-GKEIIVEGWEGAEAAKREILRAIELYK 171 + YK+L+ K + V+G+E E+A + + +AI+ Y+ Sbjct: 138 ETYKDLEPNKWVKVKGFENKESAIKVLEKAIKAYQ 172 >sp|P47593|IPYR_MYCGE INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) >gi|1361703|pir||H64238 inorganic pyrophosphatase (EC 3.6.1.1) - Mycoplasma genitalium >gi|3844935|gb|AAC71576.1| (U39717) inorganic pyrophosphatase (ppa) [Mycoplasma genitalium] Length = 184 Score = 117 bits (291), Expect = 7e-26 Identities = 59/157 (37%), Positives = 93/157 (58%) Query: 16 VVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDDDDPFDIMVI 75 ++ ++EIPK S+ KYE D++TG +++DR+L+ YP +YG I T D D D + Sbjct: 5 LIDVIVEIPKNSKIKYEYDRQTGQIRVDRILFGSESYPQNYGFIKNTLDWDGDELDCFIF 64 Query: 76 MREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKDWKDIDDVPKAFLDEIAH 135 +P P T++ R +G +MID G+ D K+L V DP +K+ I D+PK ++EI Sbjct: 65 ADQPFLPATVVPTRIVGALEMIDDGEIDTKLLGVIDCDPRYKEINQISDLPKHRIEEILI 124 Query: 136 FFKRYKELQGKEIIVEGWEGAEAAKREILRAIELYKE 172 F K YK LQ K +I++G + AK+E ++L K+ Sbjct: 125 FLKTYKLLQKKTVIIKGLKDVCWAKKEYEICLQLMKD 161 >sp|P75250|IPYR_MYCPN INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) >gi|2146322|pir||S73640 inorganic pyrophosphatase (EC 3.6.1.1) - Mycoplasma pneumoniae >gi|1673987|gb|AAB95962.1| (AE000029) inorganic pyrophosphatase [Mycoplasma pneumoniae] Length = 184 Score = 117 bits (291), Expect = 7e-26 Identities = 58/152 (38%), Positives = 90/152 (59%) Query: 21 IEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDDDDPFDIMVIMREPT 80 +EIPK S+ KYE D+KT +++DR+L+ YP +YG I T D D D + + Sbjct: 10 VEIPKSSKIKYEYDRKTSQIRVDRILFGSESYPQNYGFIANTLDWDGDELDCFIFADQAF 69 Query: 81 YPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKDWKDIDDVPKAFLDEIAHFFKRY 140 P ++ R +G +M+D G+ D K+L V DP +K+ ++D+PK +DEI F K Y Sbjct: 70 LPGVVVPTRIVGALEMVDDGELDTKLLGVIDCDPRYKEINSVNDLPKHRVDEIIGFLKTY 129 Query: 141 KELQGKEIIVEGWEGAEAAKREILRAIELYKE 172 K LQ KE+I++G + E AK+E ++L K+ Sbjct: 130 KLLQKKEVIIKGVQSLEWAKKEYQVCVDLMKQ 161 >pir||E81412 inorganic pyrophosphatase (EC 3.6.1.1) Cj0638c [imported] - Campylobacter jejuni (strain NCTC 11168) >gi|6968105|emb|CAB75274.1| (AL139075) inorganic pyrophosphatase [Campylobacter jejuni] Length = 172 Score = 113 bits (281), Expect = 1e-24 Identities = 65/163 (39%), Positives = 97/163 (58%), Gaps = 3/163 (1%) Query: 12 NVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDDDDPFD 71 ++P + A+IEIP GS KYE+DK +G + +DRV+ S FYP +YG I T DD DP D Sbjct: 10 DIPNKINAVIEIPYGSNIKYEIDKDSGAIMVDRVMASAIFYPANYGFIANTLADDGDPVD 69 Query: 72 IMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVE--DPYFKDWKDIDDVPKAF 129 I+V+ P +I R IG+ M D D K+LAVP D + + K D+P+A Sbjct: 70 ILVLNEYPIQAGAVIPCRLIGVLIMEDESGMDEKLLAVPNSKIDARYDNIKTYTDLPQAT 129 Query: 130 LDEIAHFFKRYKELQ-GKEIIVEGWEGAEAAKREILRAIELYK 171 L++I +FF+ YK L+ K + V+ ++ +AA + +AI+ YK Sbjct: 130 LNKIKNFFETYKILEPNKWVKVQDFKDEKAAIEILEKAIKNYK 172 >sp|P57190|IPYR_BUCAI INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) >gi|10038773|dbj|BAB12808.1| (AP001118) inorganic pyrophosphatase [Buchnera sp. APS] Length = 182 Score = 111 bits (274), Expect = 7e-24 Identities = 60/158 (37%), Positives = 88/158 (54%), Gaps = 4/158 (2%) Query: 10 GPNVPEVVYALIEIPKGSRN-KYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDDDD 68 G ++P +Y +IEI S KYE+DKK+G+L +DR + +P FYP +YG I T D D Sbjct: 9 GDDIPNDIYVIIEISSNSSPIKYEVDKKSGMLFVDRFIPTPMFYPCNYGYINHTLSLDGD 68 Query: 69 PFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVED--PYFKDWKDIDDVP 126 P D++V P +I +PIG+ M D D K++AVP +K+ DI D+ Sbjct: 69 PLDVLVPSHYPIKSSCVIHCKPIGILNMQDESGDDAKIIAVPKSKICQEYKNINDISDIS 128 Query: 127 KAFLDEIAHFFKRYKELQ-GKEIIVEGWEGAEAAKREI 163 + +I HFF+ YK L+ K + + GW + AK EI Sbjct: 129 ELLKKQITHFFQNYKTLEKEKWVEIIGWGNCQDAKLEI 166 >sp|Q9RGQ1|IPYR_RHORU INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) >gi|6650713|gb|AAF21981.1|AF115341_1 (AF115341) cytoplasmic pyrophosphatase [Rhodospirillum rubrum] Length = 179 Score = 107 bits (265), Expect = 8e-23 Identities = 61/162 (37%), Positives = 89/162 (54%), Gaps = 4/162 (2%) Query: 10 GPNVPEVVYALIEIPK-GSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDDDD 68 G N P+ V +IEIP KYE+DK++G + +DR L++ YP +YG +P T DD D Sbjct: 9 GKNPPQDVNVIIEIPLLADPVKYEVDKESGAMFVDRFLHTAMHYPCNYGFVPHTLSDDGD 68 Query: 69 PFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVED--PYFKDWKDIDDVP 126 P D+MV+ R P +++ RP+G+ M D +D K+L VP PY + + D+ Sbjct: 69 PVDVMVVGRIPVAVGSVMRTRPVGVLYMEDEAGRDEKILGVPHSKLYPYHDNVNNFGDLR 128 Query: 127 KAFLDEIAHFFKRYKEL-QGKEIIVEGWEGAEAAKREILRAI 167 L I HFF YK+L +GK + + GW + A I R I Sbjct: 129 PIELRRIEHFFAHYKDLEEGKWVKILGWGNYKEAWDVIERGI 170 >pir||B82908 inorganic pyrophosphatase UU315 [imported] - Ureaplasma urealyticum >gi|6899291|gb|AAF30724.1|AE002128_12 (AE002128) inorganic pyrophosphatase [Ureaplasma urealyticum] Length = 181 Score = 107 bits (264), Expect = 1e-22 Identities = 57/152 (37%), Positives = 84/152 (54%) Query: 21 IEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDDDDPFDIMVIMREPT 80 IEIPK S KYE D+ T + +DR+L+ YP +YG + D D D++V + Sbjct: 7 IEIPKNSNIKYEYDRATKEIMVDRILHGSMVYPHNYGFLKEALDYDGDELDVLVFADQAF 66 Query: 81 YPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKDWKDIDDVPKAFLDEIAHFFKRY 140 P + AR +G KMID G+ D K+LAV DP +K + D+P +L E+ FF+ Y Sbjct: 67 QPGIKVPARVLGAMKMIDGGETDTKLLAVIDVDPRYKHINNFKDIPLHWLAEVQDFFENY 126 Query: 141 KELQGKEIIVEGWEGAEAAKREILRAIELYKE 172 K LQ K++ + G+E A++E + L KE Sbjct: 127 KNLQNKKVKILGFEDEIWAQKEYEECVLLMKE 158 >sp|Q9ZCW5|IPYR_RICPR INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) >gi|7436019|pir||H71663 inorganic pyrophosphatase (ppa) RP589 - Rickettsia prowazekii >gi|3861134|emb|CAA15034.1| (AJ235272) INORGANIC PYROPHOSPHATASE (ppa) [Rickettsia prowazekii] Length = 172 Score = 106 bits (262), Expect = 2e-22 Identities = 59/156 (37%), Positives = 87/156 (54%), Gaps = 4/156 (2%) Query: 17 VYALIEIPKGSRN-KYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDDDDPFDIMVI 75 + +IEIP S KYE DK++G L +DR + + YP +YG IP T +D DP D++V+ Sbjct: 15 INVIIEIPMNSGPIKYEFDKESGALFVDRFMQTTMSYPCNYGFIPDTLSNDGDPVDVLVV 74 Query: 76 MREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVE--DPYFKDWKDIDDVPKAFLDEI 133 P P ++I+ R IG+ M D D K++AVP D F K++DD+ + I Sbjct: 75 AHHPVVPGSVIKCRAIGVLMMEDESGLDEKIIAVPTSKLDITFDHIKELDDLCEMLKKRI 134 Query: 134 AHFFKRYKELQ-GKEIIVEGWEGAEAAKREILRAIE 168 HFF+ YK+L+ GK + V GW A+ I I+ Sbjct: 135 VHFFEHYKDLEKGKWVKVTGWGDKVKAETLIKEGID 170 >emb|CAB37742.1| (AJ239631) inorganic pyrophosphatase [Helicobacter pylori] Length = 132 Score = 106 bits (262), Expect = 2e-22 Identities = 56/131 (42%), Positives = 82/131 (61%), Gaps = 3/131 (2%) Query: 27 SRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDDDDPFDIMVIMREPTYPLTII 86 S KYELDK++G L +DRVLY YP +YG +P T D DP D++V+ +++ Sbjct: 1 SNIKYELDKESGALMVDRVLYGAQNYPANYGFVPNTLGSDGDPVDVLVLSDVAFQAGSVV 60 Query: 87 EARPIGLFKMIDSGDKDYKVLAVPVE--DPYFKDWKDIDDVPKAFLDEIAHFFKRYKELQ 144 +AR +G+ M D D K+LA+P++ DP KDIDD+ K LD+I HFF+ YK+L+ Sbjct: 61 KARLVGVLNMEDESGMDEKLLALPIDKIDPTHSYVKDIDDLSKHTLDKIKHFFETYKDLE 120 Query: 145 -GKEIIVEGWE 154 K + V+G+E Sbjct: 121 PNKWVKVKGFE 131 >emb|CAB37755.1| (AJ239644) inorganic pyrophosphatase [Helicobacter pylori] Length = 132 Score = 106 bits (261), Expect = 2e-22 Identities = 57/131 (43%), Positives = 81/131 (61%), Gaps = 3/131 (2%) Query: 27 SRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDDDDPFDIMVIMREPTYPLTII 86 S KYELDKK+G L +DRVLY YP +YG +P T D DP D +V+ +++ Sbjct: 1 SNIKYELDKKSGALMVDRVLYGAQNYPANYGFVPNTLGSDGDPVDALVLSDVAFQAGSVV 60 Query: 87 EARPIGLFKMIDSGDKDYKVLAVPVE--DPYFKDWKDIDDVPKAFLDEIAHFFKRYKELQ 144 +AR +G+ M D D K+LA+P++ DP KDIDD+ K LD+I HFF+ YK+L+ Sbjct: 61 KARLVGVLNMEDESGVDEKLLALPIDKIDPTHSYVKDIDDLSKHTLDKIKHFFETYKDLE 120 Query: 145 -GKEIIVEGWE 154 K + V+G+E Sbjct: 121 PNKWVKVKGFE 131 >emb|CAB37740.1| (AJ239629) inorganic pyrophosphatase [Helicobacter pylori] Length = 132 Score = 105 bits (260), Expect = 3e-22 Identities = 55/131 (41%), Positives = 82/131 (61%), Gaps = 3/131 (2%) Query: 27 SRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDDDDPFDIMVIMREPTYPLTII 86 S KYELDK++G L +DRVLY YP +YG +P T D DP D++V+ +++ Sbjct: 1 SNIKYELDKESGALMVDRVLYGAQNYPANYGFVPNTLGSDGDPVDVLVLSDVAFQAGSVV 60 Query: 87 EARPIGLFKMIDSGDKDYKVLAVPVE--DPYFKDWKDIDDVPKAFLDEIAHFFKRYKELQ 144 +AR +G+ M D D K++A+P++ DP KDIDD+ K LD+I HFF+ YK+L+ Sbjct: 61 KARLVGVLNMEDESGMDEKLIALPIDKIDPTHSYVKDIDDLSKHTLDKIKHFFETYKDLE 120 Query: 145 -GKEIIVEGWE 154 K + V+G+E Sbjct: 121 PNKWVKVKGFE 131 >emb|CAB37738.1| (AJ239627) inorganic pyrophosphatase [Helicobacter pylori] Length = 132 Score = 104 bits (258), Expect = 5e-22 Identities = 56/131 (42%), Positives = 81/131 (61%), Gaps = 3/131 (2%) Query: 27 SRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDDDDPFDIMVIMREPTYPLTII 86 S KYELDK++G L +DRVLY YP +YG +P T D DP D +V+ +++ Sbjct: 1 SNIKYELDKESGALMVDRVLYGAQNYPTNYGFVPNTLGSDGDPVDALVLSDVAFQAGSVV 60 Query: 87 EARPIGLFKMIDSGDKDYKVLAVPVE--DPYFKDWKDIDDVPKAFLDEIAHFFKRYKELQ 144 +AR +G+ M D D K+LA+P++ DP KDIDD+ K LD+I HFF+ YK+L+ Sbjct: 61 KARLVGVLNMEDESGMDEKLLALPIDKIDPTHSYVKDIDDLSKHTLDKIKHFFETYKDLE 120 Query: 145 -GKEIIVEGWE 154 K + V+G+E Sbjct: 121 PNKWVKVKGFE 131 >emb|CAB37739.1| (AJ239628) inorganic pyrophosphatase [Helicobacter pylori] >gi|4467579|emb|CAB37741.1| (AJ239630) inorganic pyrophosphatase [Helicobacter pylori] >gi|4467583|emb|CAB37743.1| (AJ239632) inorganic pyrophosphatase [Helicobacter pylori] >gi|4467595|emb|CAB37749.1| (AJ239638) inorganic pyrophosphatase [Helicobacter pylori] >gi|4467597|emb|CAB37750.1| (AJ239639) inorganic pyrophosphatase [Helicobacter pylori] >gi|4467601|emb|CAB37752.1| (AJ239641) inorganic pyrophosphatase [Helicobacter pylori] >gi|4467603|emb|CAB37753.1| (AJ239642) inorganic pyrophosphatase [Helicobacter pylori] >gi|4467605|emb|CAB37754.1| (AJ239643) inorganic pyrophosphatase [Helicobacter pylori] Length = 132 Score = 104 bits (258), Expect = 5e-22 Identities = 56/131 (42%), Positives = 81/131 (61%), Gaps = 3/131 (2%) Query: 27 SRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDDDDPFDIMVIMREPTYPLTII 86 S KYELDK++G L +DRVLY YP +YG +P T D DP D +V+ +++ Sbjct: 1 SNIKYELDKESGALMVDRVLYGAQNYPANYGFVPNTLGSDGDPVDALVLSDVAFQAGSVV 60 Query: 87 EARPIGLFKMIDSGDKDYKVLAVPVE--DPYFKDWKDIDDVPKAFLDEIAHFFKRYKELQ 144 +AR +G+ M D D K+LA+P++ DP KDIDD+ K LD+I HFF+ YK+L+ Sbjct: 61 KARLVGVLNMEDESGMDEKLLALPIDKIDPTHSYVKDIDDLSKHTLDKIKHFFETYKDLE 120 Query: 145 -GKEIIVEGWE 154 K + V+G+E Sbjct: 121 PNKWVKVKGFE 131 >emb|CAB37737.1| (AJ239626) inorganic pyrophosphatase [Helicobacter pylori] >gi|4467585|emb|CAB37744.1| (AJ239633) inorganic pyrophosphatase [Helicobacter pylori] >gi|4467589|emb|CAB37746.1| (AJ239635) inorganic pyrophosphatase [Helicobacter pylori] >gi|4467591|emb|CAB37747.1| (AJ239636) inorganic pyrophosphatase [Helicobacter pylori] Length = 132 Score = 104 bits (257), Expect = 7e-22 Identities = 56/131 (42%), Positives = 81/131 (61%), Gaps = 3/131 (2%) Query: 27 SRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDDDDPFDIMVIMREPTYPLTII 86 S KYELDK++G L +DRVLY YP +YG +P T D DP D +V+ +++ Sbjct: 1 SNIKYELDKESGALMVDRVLYGAQNYPANYGFVPNTLGSDGDPVDALVLSDVAFQAGSVV 60 Query: 87 EARPIGLFKMIDSGDKDYKVLAVPVE--DPYFKDWKDIDDVPKAFLDEIAHFFKRYKELQ 144 +AR +G+ M D D K+LA+P++ DP KDIDD+ K LD+I HFF+ YK+L+ Sbjct: 61 KARLVGVLNMEDESGVDEKLLALPIDKIDPTHSYVKDIDDLSKHTLDKIKHFFETYKDLE 120 Query: 145 -GKEIIVEGWE 154 K + V+G+E Sbjct: 121 PNKWVKVKGFE 131 >emb|CAB37748.1| (AJ239637) inorganic pyrophosphatase [Helicobacter pylori] Length = 132 Score = 104 bits (256), Expect = 9e-22 Identities = 55/131 (41%), Positives = 81/131 (60%), Gaps = 3/131 (2%) Query: 27 SRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDDDDPFDIMVIMREPTYPLTII 86 S KYELDK++G L +DRVLY YP +YG +P T D DP D +V+ +++ Sbjct: 1 SNIKYELDKESGALMVDRVLYGAQNYPANYGFVPNTLGSDGDPVDALVLSDVAFQAGSVV 60 Query: 87 EARPIGLFKMIDSGDKDYKVLAVPVE--DPYFKDWKDIDDVPKAFLDEIAHFFKRYKELQ 144 +AR +G+ M D D K++A+P++ DP KDIDD+ K LD+I HFF+ YK+L+ Sbjct: 61 KARLVGVLNMEDESGMDEKLIALPIDKIDPTHSYVKDIDDLSKHTLDKIKHFFETYKDLE 120 Query: 145 -GKEIIVEGWE 154 K + V+G+E Sbjct: 121 PNKWVKVKGFE 131 >emb|CAB37751.1| (AJ239640) inorganic pyrophosphatase [Helicobacter pylori] Length = 132 Score = 104 bits (256), Expect = 9e-22 Identities = 55/131 (41%), Positives = 81/131 (60%), Gaps = 3/131 (2%) Query: 27 SRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDDDDPFDIMVIMREPTYPLTII 86 S KYELDK++G L +DRVLY YP +YG +P T D DP D +V+ +++ Sbjct: 1 SNIKYELDKESGALMVDRVLYGAQNYPANYGFVPNTLGSDGDPIDALVLSDVVFQAGSVV 60 Query: 87 EARPIGLFKMIDSGDKDYKVLAVPVE--DPYFKDWKDIDDVPKAFLDEIAHFFKRYKELQ 144 +AR +G+ M D D K++A+P++ DP KDIDD+ K LD+I HFF+ YK+L+ Sbjct: 61 KARLVGVLNMEDESGMDEKLIALPIDKIDPTHSYVKDIDDLSKHTLDKIKHFFETYKDLE 120 Query: 145 -GKEIIVEGWE 154 K + V+G+E Sbjct: 121 PNKWVKVKGFE 131 >pir||F81175 inorganic pyrophosphatase NMB0641 [imported] - Neisseria meningitidis (group B strain MD58) >gi|7225870|gb|AAF41064.1| (AE002419) inorganic pyrophosphatase [Neisseria meningitidis MC58] Length = 177 Score = 104 bits (256), Expect = 9e-22 Identities = 57/169 (33%), Positives = 94/169 (54%), Gaps = 2/169 (1%) Query: 7 LEPGPNVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDD 66 L PG ++ + EIP GS +K E ++K +LDRV + F P +YG IP+T +D Sbjct: 8 LTPGDVDGGIINVVNEIPAGSNHKIEWNRKLAAFQLDRVEPAIFAKPTNYGFIPQTLDED 67 Query: 67 DDPFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKD-WKDIDDV 125 D D++++ +P +EAR IG+ K +D G+ D K++ VP +D + +K + D+ Sbjct: 68 GDELDVLLVTEQPLATGVFLEARVIGVMKFVDDGEVDDKIVCVPADDRNNGNAYKTLSDL 127 Query: 126 PKAFLDEIAHFFKRYKEL-QGKEIIVEGWEGAEAAKREILRAIELYKEK 173 P+ + +I F YK+L + VE W AE AK+ I +IE + ++ Sbjct: 128 PQQLIKQIEFHFNHYKDLKKAGTTKVESWGDAEEAKKVIKESIERWNKQ 176 >emb|CAB37745.1| (AJ239634) inorganic pyrophosphatase [Helicobacter pylori] Length = 132 Score = 102 bits (253), Expect = 2e-21 Identities = 55/131 (41%), Positives = 81/131 (60%), Gaps = 3/131 (2%) Query: 27 SRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDDDDPFDIMVIMREPTYPLTII 86 S KYELDK++G L +DRVLY YP +YG +P T D DP D +V+ +++ Sbjct: 1 SNIKYELDKESGALMVDRVLYGAQNYPANYGFVPNTLGSDGDPVDALVLSDVAFQAGSVV 60 Query: 87 EARPIGLFKMIDSGDKDYKVLAVPVE--DPYFKDWKDIDDVPKAFLDEIAHFFKRYKELQ 144 +AR +G+ M D D K+LA+P++ DP KDI+D+ K LD+I HFF+ YK+L+ Sbjct: 61 KARLVGVLNMEDESGMDEKLLALPIDKIDPTHSYVKDINDLSKHTLDKIKHFFETYKDLE 120 Query: 145 -GKEIIVEGWE 154 K + V+G+E Sbjct: 121 PNKWVKVKGFE 131 >pir||G81930 probable inorganic pyrophosphatase (EC 3.6.1.1) NMA0851 [imported] - Neisseria meningitidis (group A strain Z2491) >gi|7379567|emb|CAB84132.1| (AL162754) putative inorganic pyrophosphatase [Neisseria meningitidis Z2491] Length = 177 Score = 101 bits (249), Expect = 6e-21 Identities = 54/160 (33%), Positives = 91/160 (56%), Gaps = 2/160 (1%) Query: 16 VVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDDDDPFDIMVI 75 ++ + EIP GS +K E ++K +LDRV + F P +YG IP+T +D D D++++ Sbjct: 17 IINVVNEIPAGSNHKIEWNRKLAAFQLDRVEPAIFAKPTNYGFIPQTLDEDGDELDVLLV 76 Query: 76 MREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKD-WKDIDDVPKAFLDEIA 134 +P +EAR IG+ K +D G+ D K++ VP +D + +K + D+P+ + +I Sbjct: 77 TEQPLATGVFLEARVIGVMKFVDDGEVDDKIVCVPADDRNNGNAYKTLADLPQQLIKQIE 136 Query: 135 HFFKRYKEL-QGKEIIVEGWEGAEAAKREILRAIELYKEK 173 F YK+L + VE W AE AK+ I +IE + ++ Sbjct: 137 FHFNHYKDLKKAGTTKVESWGDAEEAKKVIKESIERWNKQ 176 >sp|P44529|IPYR_HAEIN INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) >gi|1074929|pir||G64049 inorganic pyrophosphatase homolog - Haemophilus influenzae (strain Rd KW20) >gi|1573079|gb|AAC21798.1| (U32698) inorganic pyrophosphatase (ppa) [Haemophilus influenzae Rd] Length = 176 Score = 96.0 bits (235), Expect = 3e-19 Identities = 55/169 (32%), Positives = 89/169 (52%), Gaps = 2/169 (1%) Query: 7 LEPGPNVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDD 66 L PG ++ + EIP+GS +K E ++K +LDRV + F P +YG IP+T +D Sbjct: 8 LTPGDVDAGIINVVNEIPEGSCHKIEWNRKVAAFQLDRVEPAIFAKPTNYGFIPQTLDED 67 Query: 67 DDPFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVED-PYFKDWKDIDDV 125 D D+++I R+P +EA+ IG+ K +D G+ D K++ VP +D + + D+ Sbjct: 68 GDELDVLLITRQPLATGVFLEAKVIGVMKFVDDGEVDDKIVCVPADDRDTGNAYNSLADL 127 Query: 126 PKAFLDEIAHFFKRYKELQGK-EIIVEGWEGAEAAKREILRAIELYKEK 173 P + +I F YK L+ V W E AK I +I+ + E+ Sbjct: 128 PANLIKQIEFHFNNYKALKKPGSTKVTHWGDVEEAKEVIRESIKRWNER 176 >pir||A81736 inorganic pyrophosphatase, probable TC0153 [imported] - Chlamydia muridarum (strain Nigg) >gi|7190190|gb|AAF39030.1| (AE002282) inorganic pyrophosphatase, putative [Chlamydia muridarum] Length = 209 Score = 89.3 bits (218), Expect = 3e-17 Identities = 64/186 (34%), Positives = 93/186 (49%), Gaps = 26/186 (13%) Query: 15 EVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDD-------- 66 E + IEI K+ELDK+TGLLK+DR F P YG++P+T+ D Sbjct: 23 ESLCCYIEITPSDSVKFELDKETGLLKVDRPQKFSNFCPCLYGLLPKTYCGDLSGEYSGQ 82 Query: 67 ----------DDPFDIMVIMREP-TYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPY 115 DP DI V+ + T +++ARPIG +++DSG+ D K++AV +D Sbjct: 83 QSNRDNIKGDGDPLDICVLTEKNITQGNILLQARPIGGIRILDSGEADDKIIAVLEDDLV 142 Query: 116 FKDWKDIDDVPKAFLDEIAHFFKRYKE-----LQGKEIIVE--GWEGAEAAKREILRAIE 168 + +DI D P + LD I H+F YK +Q K +E G G + A++ I A E Sbjct: 143 YGAMEDISDCPGSVLDMIQHYFLTYKATPESLIQAKPAKIEIIGLYGKKEAQKVIRLAHE 202 Query: 169 LYKEKF 174 Y F Sbjct: 203 DYCNLF 208 >sp|Q9Z6Y8|IPYR_CHLPN INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) >gi|7436038|pir||E72020 inorganic pyrophosphatase CP0948 [imported] - Chlamydophila pneumoniae (strains CWL029 and AR39) >gi|4377239|gb|AAD19056.1| (AE001671) Inorganic Pyrophosphatase [Chlamydophila pneumoniae CWL029] >gi|7189861|gb|AAF38730.1| (AE002253) inorganic pyrophosphatase [Chlamydophila pneumoniae AR39] >gi|8979292|dbj|BAA99126.1| (AP002548) inorganic pyrophosphatase [Chlamydophila pneumoniae J138] Length = 215 Score = 88.9 bits (217), Expect = 3e-17 Identities = 66/200 (33%), Positives = 98/200 (49%), Gaps = 26/200 (13%) Query: 2 NPFHDLEPGPNVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPR 61 +P+H + E + IEI K+ELDK TGLLK+DR F P YG++P+ Sbjct: 10 HPWHSPTLTQDNYESLCCYIEITPYDSVKFELDKATGLLKVDRPQKFSNFCPCLYGLLPQ 69 Query: 62 TW------------------YDDDDPFDIMVIMREPTYPLTII-EARPIGLFKMIDSGDK 102 T+ D DP D+ V+ + + I+ +ARPIG ++IDSG+ Sbjct: 70 TYCGTASGNYSGEQTRREGIQGDKDPLDVCVLTEKNIHHGNILLQARPIGGLRIIDSGEA 129 Query: 103 DYKVLAVPVEDPYFKDWKDIDDVPKAFLDEIAHFFKRYKE-----LQGK--EIIVEGWEG 155 D K++AV +D F + +DI D P LD I H+F YK ++G +I + G G Sbjct: 130 DDKIIAVLEDDLVFAEIEDISDCPGTVLDMIQHYFLTYKATPNHLIKGSPAKIEIVGIYG 189 Query: 156 AEAAKREILRAIELYKEKFG 175 + A++ I A E Y G Sbjct: 190 KKEAQKVIQLAHEDYLSYIG 209 >sp|P37980|IPYR_BOVIN INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) >gi|539751|pir||A45153 inorganic pyrophosphatase (EC 3.6.1.1) - bovine Length = 289 Score = 84.3 bits (205), Expect = 9e-16 Identities = 56/172 (32%), Positives = 87/172 (50%), Gaps = 27/172 (15%) Query: 1 MNPFHDLEPGPNVPEVVYALIEIPKGSRNKYEL-----------DKKTGLLKLDRVLYSP 49 ++PFHD+ P EV + ++E+P+ S K E+ D K G L+ L+ Sbjct: 29 ISPFHDI-PIYADKEVFHMVVEVPRWSNAKMEIATKDPLNPIKQDVKKGKLRYVANLFPY 87 Query: 50 FFYPVDYGIIPRTWYD------------DDDPFDIMVIMREPTYPLTIIEARPIGLFKMI 97 Y +YG IP+TW D D+DP D+ I + II + +G+ MI Sbjct: 88 KGYIWNYGAIPQTWEDPGHNDKHTGCCGDNDPIDVCEIGSKVCARGEIIRVKVLGILAMI 147 Query: 98 DSGDKDYKVLAVPVEDPYFKDWKDIDDVPK---AFLDEIAHFFKRYKELQGK 146 D G+ D+KV+A+ VEDP ++ DI+DV + +L+ +F+RYK GK Sbjct: 148 DEGETDWKVIAINVEDPDAANYNDINDVKRLKPGYLEATVDWFRRYKVPDGK 199 >sp|O84777|IPYR_CHLTR INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) >gi|7436029|pir||G71473 probable inorganic pyrophosphatase - Chlamydia trachomatis (serotype D, strain UW3/Cx) >gi|3329235|gb|AAC68367.1| (AE001349) Inorganic Pyrophosphatase [Chlamydia trachomatis] Length = 209 Score = 83.9 bits (204), Expect = 1e-15 Identities = 61/186 (32%), Positives = 93/186 (49%), Gaps = 26/186 (13%) Query: 15 EVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPRTWYDD-------- 66 E + IEI K+ELDK+TG+LK+DR F P YG++P+T+ D Sbjct: 23 ESLCCYIEITPADSVKFELDKETGILKVDRPQKFSNFCPCLYGLLPKTYCGDLSGEYSGQ 82 Query: 67 ----------DDPFDIMVIMREP-TYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPY 115 DP DI V+ + T +++ARPIG +++DS + D K++AV +D Sbjct: 83 QSNRENIKGDGDPLDICVLTEKNITQGNILLQARPIGGIRILDSEEADDKIIAVLEDDLV 142 Query: 116 FKDWKDIDDVPKAFLDEIAHFFKRYKE-----LQGK--EIIVEGWEGAEAAKREILRAIE 168 + + +DI + P LD I H+F YK +Q K +I + G G + A++ I A E Sbjct: 143 YGNIEDISECPGTVLDMIQHYFLTYKATPESLIQAKPAKIEIVGLYGKKEAQKVIRLAHE 202 Query: 169 LYKEKF 174 Y F Sbjct: 203 DYCNLF 208 >gb|AAD24964.1| (AF108211) cytosolic inorganic pyrophosphatase [Homo sapiens] Length = 282 Score = 81.1 bits (197), Expect = 8e-15 Identities = 54/172 (31%), Positives = 87/172 (50%), Gaps = 27/172 (15%) Query: 1 MNPFHDLEPGPNVPEVVYALIEIPKGSRNKYEL-----------DKKTGLLKLDRVLYSP 49 ++PFHD+ P +V + ++E+P+ S K E+ D K G L+ L+ Sbjct: 25 ISPFHDI-PIYADKDVFHMVVEVPRWSNAKMEIATKDPLNPIKQDVKKGKLRYVANLFPY 83 Query: 50 FFYPVDYGIIPRTWYD------------DDDPFDIMVIMREPTYPLTIIEARPIGLFKMI 97 Y +YG IP+TW D D+DP D+ I + II + +G+ MI Sbjct: 84 KGYIWNYGAIPQTWEDPGHNDKHTGCCGDNDPIDVCEIGSKVCARGEIIGVKVLGILAMI 143 Query: 98 DSGDKDYKVLAVPVEDPYFKDWKDIDDVPK---AFLDEIAHFFKRYKELQGK 146 D G+ D+KV+A+ V+DP ++ DI+DV + +L+ +F+RYK GK Sbjct: 144 DEGETDWKVIAINVDDPDAANYNDINDVKRLKPGYLEATVDWFRRYKVPDGK 195 >gi|11056044 pyrophosphatase (inorganic); inorganic pyrophosphatase [Homo sapiens] >gi|8247940|sp|Q15181|IPYR_HUMAN INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) >gi|4960208|gb|AAD34643.1|AF154065_1 (AF154065) inorganic pyrophosphatase [Homo sapiens] >gi|5931602|dbj|BAA84702.1| (AB026723) pyrophosphatase [Homo sapiens] >gi|6563256|gb|AAF17222.1|AF119665_1 (AF119665) inorganic pyrophosphatase [Homo sapiens] >gi|11526787|gb|AAG36780.1|AF217186_1 (AF217186) inorganic pyrophosphatase 1 [Homo sapiens] Length = 289 Score = 81.1 bits (197), Expect = 8e-15 Identities = 54/172 (31%), Positives = 87/172 (50%), Gaps = 27/172 (15%) Query: 1 MNPFHDLEPGPNVPEVVYALIEIPKGSRNKYEL-----------DKKTGLLKLDRVLYSP 49 ++PFHD+ P +V + ++E+P+ S K E+ D K G L+ L+ Sbjct: 29 ISPFHDI-PIYADKDVFHMVVEVPRWSNAKMEIATKDPLNPIKQDVKKGKLRYVANLFPY 87 Query: 50 FFYPVDYGIIPRTWYD------------DDDPFDIMVIMREPTYPLTIIEARPIGLFKMI 97 Y +YG IP+TW D D+DP D+ I + II + +G+ MI Sbjct: 88 KGYIWNYGAIPQTWEDPGHNDKHTGCCGDNDPIDVCEIGSKVCARGEIIGVKVLGILAMI 147 Query: 98 DSGDKDYKVLAVPVEDPYFKDWKDIDDVPK---AFLDEIAHFFKRYKELQGK 146 D G+ D+KV+A+ V+DP ++ DI+DV + +L+ +F+RYK GK Sbjct: 148 DEGETDWKVIAINVDDPDAANYNDINDVKRLKPGYLEATVDWFRRYKVPDGK 199 >gb|AAD50298.1|AF174582_1 (AF174582) inorganic pyrophosphatase [Torpedo marmorata] Length = 288 Score = 79.2 bits (192), Expect = 3e-14 Identities = 49/173 (28%), Positives = 87/173 (49%), Gaps = 27/173 (15%) Query: 1 MNPFHDLEPGPNVPEVVYALI-EIPKGSRNKYEL-----------DKKTGLLKLDRVLYS 48 ++PFHD+ + + V+ ++ E+P+ + K E+ D K G L+ ++ Sbjct: 27 VSPFHDIPLWASESQNVFNMVVEVPRWTNAKMEIATKEPLNPIKQDIKKGNLRYVANIFP 86 Query: 49 PFFYPVDYGIIPRTWYD------------DDDPFDIMVIMREPTYPLTIIEARPIGLFKM 96 Y +YG +P+TW D D+DP D+ I + +I+ + +G+ M Sbjct: 87 HKGYIWNYGALPQTWEDPNHTDELTGCAGDNDPIDVCEIGTKVCTRGEVIQVKVLGILAM 146 Query: 97 IDSGDKDYKVLAVPVEDP---YFKDWKDIDDVPKAFLDEIAHFFKRYKELQGK 146 ID G+ D+K++A+ V+DP F D +D+ DV +L+ +F+RYK GK Sbjct: 147 IDEGETDWKIIAIDVKDPEEDKFNDIEDVKDVKPGYLEATVDWFRRYKVPDGK 199 >pir||S77798 probable inorganic pyrophosphatase (EC 3.6.1.1) - Mycoplasma capricolum (fragment) Length = 136 Score = 78.8 bits (191), Expect = 4e-14 Identities = 38/118 (32%), Positives = 65/118 (54%), Gaps = 3/118 (2%) Query: 59 IPRTWYDDDDPFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKD 118 +P+ + D DP D++ + PT P ++ R +G KM+ +G+ D K+ V +DP FK+ Sbjct: 9 VPKHYSWDGDPLDVISLCTYPTLPGVXVDIRILGSIKMVXAGEVDTKLFGVFNDDPRFKE 68 Query: 119 WKDIDDVPKAFLDEIAHFFKRYKELQGKEIIVEGWEGAEAAKREILRA---IELYKEK 173 ++ ++DVPK + FF +YK LQ K + + GW + A E+ E YK++ Sbjct: 69 YQTLNDVPKHYXXXXXXFFLQYKALQNKVVRINGWGTLDXALEELEECKARFEEYKDR 126 >emb|CAA83823.1| (Z33286) inorganic pyrophosphatase [Mycoplasma capricolum] Length = 136 Score = 78.4 bits (190), Expect = 5e-14 Identities = 38/118 (32%), Positives = 65/118 (54%), Gaps = 3/118 (2%) Query: 59 IPRTWYDDDDPFDIMVIMREPTYPLTIIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFKD 118 +P+ + D DP D++ + PT P ++ R +G KM+ +G+ D K+ V +DP FK+ Sbjct: 9 VPKHYSWDGDPLDVISLCTYPTLPGVXVDIRILGSIKMVXAGEVDTKLFGVFNDDPRFKE 68 Query: 119 WKDIDDVPKAFLDEIAHFFKRYKELQGKEIIVEGWEGAEAAKREILRA---IELYKEK 173 ++ ++DVPK + FF +YK LQ K + + GW + A E+ E YK++ Sbjct: 69 YQTLNDVPKHYRXXXXXFFLQYKALQNKVVRINGWGTLDXALEELEECKARFEEYKDR 126 >pir||T49933 inorganic pyrophosphatase-like protein - Arabidopsis thaliana >gi|7671424|emb|CAB89365.1| (AL353994) inorganic pyrophosphatase-like protein [Arabidopsis thaliana] >gi|9758993|dbj|BAB09520.1| (AB020752) inorganic pyrophosphatase-like protein [Arabidopsis thaliana] Length = 300 Score = 73.7 bits (178), Expect = 1e-12 Identities = 57/196 (29%), Positives = 95/196 (48%), Gaps = 23/196 (11%) Query: 1 MNPFHDLEPGPNVPEVVYALIEIPKGSRNKYEL--DKKTGLLKLD----RVLYSPFFYPV 54 ++P+HD+ P V ++EIPK S+ K E+ D+ +K D ++ Y P+ Sbjct: 90 VSPWHDI-PLTLGDGVFNFIVEIPKESKAKMEVATDEDFTPIKQDTKKGKLRYYPYNINW 148 Query: 55 DYGIIPRTWYD-------------DDDPFDIMVIMREPTYPLTIIEARPIGLFKMIDSGD 101 +YG++P+TW D D+DP D++ I I++ +P+ MID G+ Sbjct: 149 NYGLLPQTWEDPSHANSEVEGCFGDNDPVDVVEIGETQRKIGDILKIKPLAALAMIDEGE 208 Query: 102 KDYKVLAVPVEDPYFKDWKDIDDVPKAF---LDEIAHFFKRYKELQGKEIIVEGWEGAEA 158 D+K++A+ ++DP D++DV K F L I +F+ YK GK G A Sbjct: 209 LDWKIVAISLDDPKAHLVNDVEDVEKHFPGTLTAIRDWFRDYKIPDGKPANRFGLGDKPA 268 Query: 159 AKREILRAIELYKEKF 174 K L+ I+ E + Sbjct: 269 NKDYALKIIQETNESW 284 >pdb|8PRK|B Chain B, The R78k And D117e Active Site Variants Of Saccharomyces Cerevisiae Soluble Inorganic Pyrophosphatase: Structural Studies And Mechanistic Implications >gi|6729855|pdb|8PRK|A Chain A, The R78k And D117e Active Site Variants Of Saccharomyces Cerevisiae Soluble Inorganic Pyrophosphatase: Structural Studies And Mechanistic Implications Length = 287 Score = 72.2 bits (174), Expect = 4e-12 Identities = 54/203 (26%), Positives = 91/203 (44%), Gaps = 30/203 (14%) Query: 1 MNPFHDLEPGPNVPEVVYALI-EIPKGSRNKYEL-----------DKKTGLLKLDRVLYS 48 ++ FHD+ + ++ ++ EIP+ + K E+ D K G LK R + Sbjct: 27 VSAFHDIPLYADKENNIFNMVVEIPRWTNAKLEITKEETLNPIIQDTKKGKLKFVRNCFP 86 Query: 49 PFFYPVDYGIIPRTWYD------------DDDPFDIMVIMREPTYPLTIIEARPIGLFKM 96 Y +YG P+TW D D+DP D++ I Y + + + +G+ + Sbjct: 87 HHGYIHNYGAFPQTWEDPNVSHPETKAVGDNDPIDVLEIGETIAYTGQVKQVKALGIMAL 146 Query: 97 IDSGDKDYKVLAVPVEDPYFKDWKDIDDVPKAF---LDEIAHFFKRYKELQGKEIIVEGW 153 +D G+ D+KV+A+ + DP DI+DV K F L +F+ YK GK + Sbjct: 147 LDEGETDWKVIAIDINDPLAPKLNDIEDVEKYFPGLLRATNEWFRIYKIPDGKPENQFAF 206 Query: 154 EGAEAAKREILRAIELYKEKFGS 176 G K+ A+++ KE S Sbjct: 207 SGEAKNKK---YALDIIKETHDS 226 >sp|P00817|IPYR_YEAST INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) >gi|4199|emb|CAA31629.1| (X13253) pyrophosphatase (AA 1 - 287) [Saccharomyces cerevisiae] Length = 287 Score = 71.0 bits (171), Expect = 9e-12 Identities = 53/203 (26%), Positives = 91/203 (44%), Gaps = 30/203 (14%) Query: 1 MNPFHDLEPGPNVPEVVYALI-EIPKGSRNKYEL-----------DKKTGLLKLDRVLYS 48 ++ FHD+ + ++ ++ EIP+ + K E+ D K G L+ R + Sbjct: 27 VSAFHDIPLYADKENNIFNMVVEIPRWTNAKLEITKEETLNPIIQDTKKGKLRFVRNCFP 86 Query: 49 PFFYPVDYGIIPRTWYD------------DDDPFDIMVIMREPTYPLTIIEARPIGLFKM 96 Y +YG P+TW D D+DP D++ I Y + + + +G+ + Sbjct: 87 HHGYIHNYGAFPQTWEDPNVSHPETKAVGDNDPIDVLEIGETIAYTGQVKQVKALGIMAL 146 Query: 97 IDSGDKDYKVLAVPVEDPYFKDWKDIDDVPKAF---LDEIAHFFKRYKELQGKEIIVEGW 153 +D G+ D+KV+A+ + DP DI+DV K F L +F+ YK GK + Sbjct: 147 LDEGETDWKVIAIDINDPLAPKLNDIEDVEKYFPGLLRATNEWFRIYKIPDGKPENQFAF 206 Query: 154 EGAEAAKREILRAIELYKEKFGS 176 G K+ A+++ KE S Sbjct: 207 SGEAKNKK---YALDIIKETHDS 226 >gi|6319483 Inorganic pyrophosphatase; Ipp1p [Saccharomyces cerevisiae] >gi|625241|pir||PWBY inorganic pyrophosphatase (EC 3.6.1.1) - yeast (Saccharomyces cerevisiae) >gi|536206|emb|CAA84949.1| (Z35880) ORF YBR011c [Saccharomyces cerevisiae] Length = 287 Score = 71.0 bits (171), Expect = 9e-12 Identities = 53/203 (26%), Positives = 91/203 (44%), Gaps = 30/203 (14%) Query: 1 MNPFHDLEPGPNVPEVVYALI-EIPKGSRNKYEL-----------DKKTGLLKLDRVLYS 48 ++ FHD+ + ++ ++ EIP+ + K E+ D K G L+ R + Sbjct: 27 VSAFHDIPLYADKENNIFNMVVEIPRWTNAKLEITKEETLNPIIQDTKKGKLRFVRNCFP 86 Query: 49 PFFYPVDYGIIPRTWYD------------DDDPFDIMVIMREPTYPLTIIEARPIGLFKM 96 Y +YG P+TW D D+DP D++ I Y + + + +G+ + Sbjct: 87 HHGYIHNYGAFPQTWEDPNVSHPETKAVGDNDPIDVLEIGETIAYTGQVKQVKALGIMAL 146 Query: 97 IDSGDKDYKVLAVPVEDPYFKDWKDIDDVPKAF---LDEIAHFFKRYKELQGKEIIVEGW 153 +D G+ D+KV+A+ + DP DI+DV K F L +F+ YK GK + Sbjct: 147 LDEGETDWKVIAIDINDPLAPKLNDIEDVEKYFPGLLRATNEWFRIYKIPDGKPENQFAF 206 Query: 154 EGAEAAKREILRAIELYKEKFGS 176 G K+ A+++ KE S Sbjct: 207 SGEAKNKK---YALDIIKETHDS 226 >pdb|1WGJ|B Chain B, Structure Of Inorganic Pyrophosphatase >gi|2781302|pdb|1WGJ|A Chain A, Structure Of Inorganic Pyrophosphatase >gi|2781300|pdb|1WGI|A Chain A, Structure Of Inorganic Pyrophosphatase >gi|2781301|pdb|1WGI|B Chain B, Structure Of Inorganic Pyrophosphatase Length = 286 Score = 71.0 bits (171), Expect = 9e-12 Identities = 53/203 (26%), Positives = 91/203 (44%), Gaps = 30/203 (14%) Query: 1 MNPFHDLEPGPNVPEVVYALI-EIPKGSRNKYEL-----------DKKTGLLKLDRVLYS 48 ++ FHD+ + ++ ++ EIP+ + K E+ D K G L+ R + Sbjct: 26 VSAFHDIPLYADKENNIFNMVVEIPRWTNAKLEITKEETLNPIIQDTKKGKLRFVRNCFP 85 Query: 49 PFFYPVDYGIIPRTWYD------------DDDPFDIMVIMREPTYPLTIIEARPIGLFKM 96 Y +YG P+TW D D+DP D++ I Y + + + +G+ + Sbjct: 86 HHGYIHNYGAFPQTWEDPNVSHPETKAVGDNDPIDVLEIGETIAYTGQVKQVKALGIMAL 145 Query: 97 IDSGDKDYKVLAVPVEDPYFKDWKDIDDVPKAF---LDEIAHFFKRYKELQGKEIIVEGW 153 +D G+ D+KV+A+ + DP DI+DV K F L +F+ YK GK + Sbjct: 146 LDEGETDWKVIAIDINDPLAPKLNDIEDVEKYFPGLLRATNEWFRIYKIPDGKPENQFAF 205 Query: 154 EGAEAAKREILRAIELYKEKFGS 176 G K+ A+++ KE S Sbjct: 206 SGEAKNKK---YALDIIKETHDS 225 >pdb|1HUJ|A Chain A, Refined Structure Of Yeast Inorganic Pyrophosphatase And Its K61r Mutant >gi|3114390|pdb|1HUJ|B Chain B, Refined Structure Of Yeast Inorganic Pyrophosphatase And Its K61r Mutant Length = 281 Score = 71.0 bits (171), Expect = 9e-12 Identities = 53/203 (26%), Positives = 91/203 (44%), Gaps = 30/203 (14%) Query: 1 MNPFHDLEPGPNVPEVVYALI-EIPKGSRNKYEL-----------DKKTGLLKLDRVLYS 48 ++ FHD+ + ++ ++ EIP+ + K E+ D K G L+ R + Sbjct: 26 VSAFHDIPLYADKENNIFNMVVEIPRWTNAKLEITREETLNPIIQDTKKGKLRFVRNCFP 85 Query: 49 PFFYPVDYGIIPRTWYD------------DDDPFDIMVIMREPTYPLTIIEARPIGLFKM 96 Y +YG P+TW D D+DP D++ I Y + + + +G+ + Sbjct: 86 HHGYIHNYGAFPQTWEDPNVSHPETKAVGDNDPIDVLEIGETIAYTGQVKQVKALGIMAL 145 Query: 97 IDSGDKDYKVLAVPVEDPYFKDWKDIDDVPKAF---LDEIAHFFKRYKELQGKEIIVEGW 153 +D G+ D+KV+A+ + DP DI+DV K F L +F+ YK GK + Sbjct: 146 LDEGETDWKVIAIDINDPLAPKLNDIEDVEKYFPGLLRATNEWFRIYKIPDGKPENQFAF 205 Query: 154 EGAEAAKREILRAIELYKEKFGS 176 G K+ A+++ KE S Sbjct: 206 SGEAKNKK---YALDIIKETHDS 225 >pdb|1HUK|A Chain A, Refined Structure Of Yeast Inorganic Pyrophosphatase And Its K61r Mutant >gi|3114392|pdb|1HUK|B Chain B, Refined Structure Of Yeast Inorganic Pyrophosphatase And Its K61r Mutant Length = 281 Score = 71.0 bits (171), Expect = 9e-12 Identities = 53/203 (26%), Positives = 91/203 (44%), Gaps = 30/203 (14%) Query: 1 MNPFHDLEPGPNVPEVVYALI-EIPKGSRNKYEL-----------DKKTGLLKLDRVLYS 48 ++ FHD+ + ++ ++ EIP+ + K E+ D K G L+ R + Sbjct: 26 VSAFHDIPLYADKENNIFNMVVEIPRWTNAKLEITKEETLNPIIQDTKKGKLRFVRNCFP 85 Query: 49 PFFYPVDYGIIPRTWYD------------DDDPFDIMVIMREPTYPLTIIEARPIGLFKM 96 Y +YG P+TW D D+DP D++ I Y + + + +G+ + Sbjct: 86 HHGYIHNYGAFPQTWEDPNVSHPETKAVGDNDPIDVLEIGETIAYTGQVKQVKALGIMAL 145 Query: 97 IDSGDKDYKVLAVPVEDPYFKDWKDIDDVPKAF---LDEIAHFFKRYKELQGKEIIVEGW 153 +D G+ D+KV+A+ + DP DI+DV K F L +F+ YK GK + Sbjct: 146 LDEGETDWKVIAIDINDPLAPKLNDIEDVEKYFPGLLRATNEWFRIYKIPDGKPENQFAF 205 Query: 154 EGAEAAKREILRAIELYKEKFGS 176 G K+ A+++ KE S Sbjct: 206 SGEAKNKK---YALDIIKETHDS 225 >pir||T20014 hypothetical protein C47E12.4 - Caenorhabditis elegans >gi|5824411|emb|CAA93107.2| (Z68882) Similarity to Bovine inorganic pyrophosphatase (SW:IPYR_BOVIN), contains similarity to Pfam domain: PF00719 (Inorganic pyrophosphatase), Score=349.0, E-value=1.6e-101, N=1~cDNA EST yk102b9.3 comes from this gene~cDNA EST yk102b9.5 comes from t> Length = 350 Score = 70.6 bits (170), Expect = 1e-11 Identities = 47/173 (27%), Positives = 83/173 (47%), Gaps = 27/173 (15%) Query: 1 MNPFHDLEPGPNVPEVVYALI-EIPKGSRNKYEL-----------DKKTGLLKLDRVLYS 48 ++P+HD+ N + VY +I EIP+ + K E+ D+K G+ + ++ Sbjct: 93 VSPWHDIPLFANKDKRVYNMIVEIPRWTNAKMEMATKEPFSPIKQDEKKGVARFVHNIFP 152 Query: 49 PFFYPVDYGIIPRTWYD------------DDDPFDIMVIMREPTYPLTIIEARPIGLFKM 96 Y +YG +P+TW D D+DP D++ + + +++ + +G + Sbjct: 153 HKGYIWNYGALPQTWEDPNHVVPDTGAKGDNDPIDVIEVGSKVAGRGAVLQVKVLGTLAL 212 Query: 97 IDSGDKDYKVLAVPVEDPYFKDWKDIDDVPKAF---LDEIAHFFKRYKELQGK 146 ID G+ D+K++A+ V D DIDDV K + L +F+ YK GK Sbjct: 213 IDEGETDWKLVAIDVNDENADKLNDIDDVEKVYPGLLAASVEWFRNYKIPAGK 265 >sp|Q18680|IPYR_CAEEL PROBABLE INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) Length = 292 Score = 70.6 bits (170), Expect = 1e-11 Identities = 47/173 (27%), Positives = 83/173 (47%), Gaps = 27/173 (15%) Query: 1 MNPFHDLEPGPNVPEVVYALI-EIPKGSRNKYEL-----------DKKTGLLKLDRVLYS 48 ++P+HD+ N + VY +I EIP+ + K E+ D+K G+ + ++ Sbjct: 35 VSPWHDIPLFANKDKRVYNMIVEIPRWTNAKMEMATKEPFSPIKQDEKKGVARFVHNIFP 94 Query: 49 PFFYPVDYGIIPRTWYD------------DDDPFDIMVIMREPTYPLTIIEARPIGLFKM 96 Y +YG +P+TW D D+DP D++ + + +++ + +G + Sbjct: 95 HKGYIWNYGALPQTWEDPNHVVPDTGAKGDNDPIDVIEVGSKVAGRGAVLQVKVLGTLAL 154 Query: 97 IDSGDKDYKVLAVPVEDPYFKDWKDIDDVPKAF---LDEIAHFFKRYKELQGK 146 ID G+ D+K++A+ V D DIDDV K + L +F+ YK GK Sbjct: 155 IDEGETDWKLVAIDVNDENADKLNDIDDVEKVYPGLLAASVEWFRNYKIPAGK 207 >sp|P13998|IPYR_KLULA INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) >gi|67792|pir||PWVKL inorganic pyrophosphatase (EC 3.6.1.1) - yeast (Kluyveromyces marxianus var. lactis) >gi|2903|emb|CAA32446.1| (X14230) inorganic pyrophosphatase (AA 1-287) [Kluyveromyces lactis] Length = 287 Score = 69.9 bits (168), Expect = 2e-11 Identities = 46/173 (26%), Positives = 80/173 (45%), Gaps = 27/173 (15%) Query: 1 MNPFHDLEPGPNVPEVVYALI-EIPKGSRNKYEL-----------DKKTGLLKLDRVLYS 48 ++ FHD+ + ++ ++ EIP+ + K E+ D K G L+ R + Sbjct: 27 ISAFHDIPLYADEANGIFNMVVEIPRWTNAKLEITKEEPLNPIIQDTKKGKLRFVRNCFP 86 Query: 49 PFFYPVDYGIIPRTWYD------------DDDPFDIMVIMREPTYPLTIIEARPIGLFKM 96 Y +YG P+TW D D+DP D++ I + Y + + + +G+ + Sbjct: 87 HHGYIHNYGAFPQTWEDPNESHPETKAVGDNDPLDVLEIGEQVAYTGQVKQVKVLGVMAL 146 Query: 97 IDSGDKDYKVLAVPVEDPYFKDWKDIDDVPK---AFLDEIAHFFKRYKELQGK 146 +D G+ D+KV+A+ + DP DI+DV K L +F+ YK GK Sbjct: 147 LDEGETDWKVIAIDINDPLAPKLNDIEDVEKHLPGLLRATNEWFRIYKIPDGK 199 >pdb|1PYP| Inorganic Pyrophosphatase (E.C.3.6.1.1) Length = 285 Score = 69.9 bits (168), Expect = 2e-11 Identities = 52/202 (25%), Positives = 92/202 (44%), Gaps = 29/202 (14%) Query: 1 MNPFHDLEPGPNVPEVVYALI-EIPKGSRNKYELDKKT----------GLLKLDRVLYSP 49 ++ FHD+ + + ++ ++ EIP+ + K E+ K+ G L+ R + Sbjct: 26 VSAFHDIPLYADKEDNIFNMVVEIPRWTNAKLEITKEETLNPIIQNTKGKLRFVRNCFPH 85 Query: 50 FFYPVDYGIIPRTWYD------------DDDPFDIMVIMREPTYPLTIIEARPIGLFKMI 97 Y +YG P+TW D D++P D++ I Y + E + +G+ ++ Sbjct: 86 HGYIHNYGAFPQTWEDPNVSHPETKAVGDNNPIDVLQIGETIAYTGQVKEVKALGIMALL 145 Query: 98 DSGDKDYKVLAVPVEDPYFKDWKDIDDVPKAF---LDEIAHFFKRYKELQGKEIIVEGWE 154 D G+ D+KV+A+ + DP DI+DV K F L +F+ YK GK + Sbjct: 146 DEGETDWKVIAIDINDPLAPKLNDIEDVEKYFPGLLRATDEWFRIYKIPDGKPENQFAFS 205 Query: 155 GAEAAKREILRAIELYKEKFGS 176 G K+ A+++ KE S Sbjct: 206 GEAKNKK---YALDIIKETHNS 224 >pdb|117E|A Chain A, The R78k And D117e Active Site Variants Of Saccharomyces Cerevisiae Soluble Inorganic Pyrophosphatase: Structural Studies And Mechanistic Implications >gi|6729691|pdb|117E|B Chain B, The R78k And D117e Active Site Variants Of Saccharomyces Cerevisiae Soluble Inorganic Pyrophosphatase: Structural Studies And Mechanistic Implications Length = 286 Score = 69.5 bits (167), Expect = 3e-11 Identities = 52/203 (25%), Positives = 91/203 (44%), Gaps = 30/203 (14%) Query: 1 MNPFHDLEPGPNVPEVVYALI-EIPKGSRNKYEL-----------DKKTGLLKLDRVLYS 48 ++ FHD+ + ++ ++ EIP+ + K E+ D K G L+ R + Sbjct: 26 VSAFHDIPLYADKENNIFNMVVEIPRWTNAKLEITKEETLNPIIQDTKKGKLRFVRNCFP 85 Query: 49 PFFYPVDYGIIPRTWYD------------DDDPFDIMVIMREPTYPLTIIEARPIGLFKM 96 Y +YG P+TW D D++P D++ I Y + + + +G+ + Sbjct: 86 HHGYIHNYGAFPQTWEDPNVSHPETKAVGDNEPIDVLEIGETIAYTGQVKQVKALGIMAL 145 Query: 97 IDSGDKDYKVLAVPVEDPYFKDWKDIDDVPKAF---LDEIAHFFKRYKELQGKEIIVEGW 153 +D G+ D+KV+A+ + DP DI+DV K F L +F+ YK GK + Sbjct: 146 LDEGETDWKVIAIDINDPLAPKLNDIEDVEKYFPGLLRATNEWFRIYKIPDGKPENQFAF 205 Query: 154 EGAEAAKREILRAIELYKEKFGS 176 G K+ A+++ KE S Sbjct: 206 SGEAKNKK---YALDIIKETHDS 225 >pdb|1YPP|A Chain A, Acid Anhydride Hydrolase >gi|1942887|pdb|1YPP|B Chain B, Acid Anhydride Hydrolase Length = 286 Score = 69.1 bits (166), Expect = 3e-11 Identities = 52/203 (25%), Positives = 91/203 (44%), Gaps = 30/203 (14%) Query: 1 MNPFHDLEPGPNVPEVVYALI-EIPKGSRNKYELDKKT-----------GLLKLDRVLYS 48 ++ FHD+ + ++ ++ EIP+ + K E+ K+ G L+ R + Sbjct: 26 VSAFHDIPLYADKENNIFNMVVEIPRWTNAKLEITKEETLNPIIQDTAKGKLRFVRNCFP 85 Query: 49 PFFYPVDYGIIPRTWYD------------DDDPFDIMVIMREPTYPLTIIEARPIGLFKM 96 Y +YG P+TW D D+DP D++ I Y + + + +G+ + Sbjct: 86 HHGYIHNYGAFPQTWEDPNVSHPETKAVGDNDPIDVLEIGETIAYTGQVKQVKALGIMAL 145 Query: 97 IDSGDKDYKVLAVPVEDPYFKDWKDIDDVPKAF---LDEIAHFFKRYKELQGKEIIVEGW 153 +D G+ D+KV+A+ + DP DI+DV K F L +F+ YK GK + Sbjct: 146 LDEGETDWKVIAIDINDPLAPKLNDIEDVEKYFPGLLRATNEWFRIYKIPDGKPENQFAF 205 Query: 154 EGAEAAKREILRAIELYKEKFGS 176 G K+ A+++ KE S Sbjct: 206 SGEAKNKK---YALDIIKETHDS 225 >sp|O77460|IPYR_DROME INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) (NUCLEOSOME REMODELING FACTOR 38 KDA SUBUNIT) >gi|3600094|gb|AAC97112.1| (AF085601) inorganic pyrophosphatase NURF-38 [Drosophila melanogaster] >gi|3746880|gb|AAC97111.1| (AF085600) inorganic pyrophosphatase NURF-38 [Drosophila melanogaster] Length = 290 Score = 68.7 bits (165), Expect = 4e-11 Identities = 47/173 (27%), Positives = 80/173 (46%), Gaps = 27/173 (15%) Query: 1 MNPFHDLEPGPNVPEVVYALI-EIPKGSRNKYELDKKT-----------GLLKLDRVLYS 48 ++P HD+ N + +Y ++ E+P+ + K E+ KT G L+ + Sbjct: 29 ISPMHDIPLYANEEKTIYNMVVEVPRWTNAKMEISLKTPMNPIKQDIKKGKLRFVANCFP 88 Query: 49 PFFYPVDYGIIPRTWYD------------DDDPFDIMVIMREPTYPLTIIEARPIGLFKM 96 Y +YG +P+TW + D+DP D++ I +++ + +G F + Sbjct: 89 HKGYIWNYGALPQTWENPDHIEPSTGCKGDNDPIDVIEIGYRVAKRGDVLKVKVLGQFAL 148 Query: 97 IDSGDKDYKVLAVPVEDPYFKDWKDIDDVPKAF---LDEIAHFFKRYKELQGK 146 ID G+ D+K++A+ V DP DI DV + F L +FK YK GK Sbjct: 149 IDEGETDWKIIAIDVNDPLASKVNDIADVDQYFPGLLRATVEWFKIYKIPDGK 201 >sp|O13505|IPYR_PICPA INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) >gi|2624379|emb|CAA04453.1| (AJ001000) inorganic pyrophosphatase (pyrophosphate phospho-hydrolase) [Pichia pastoris] Length = 285 Score = 68.3 bits (164), Expect = 6e-11 Identities = 47/173 (27%), Positives = 80/173 (46%), Gaps = 28/173 (16%) Query: 1 MNPFHDLEP-GPNVPEVVYALIEIPKGSRNKYELDK-----------KTGLLKLDRVLYS 48 ++PFHD+ +V+ ++E+P+ + K E+ K K G L+ R + Sbjct: 27 VSPFHDIPLYADESKKVLNMVVEVPRWTNAKLEISKEEKLNPILQDTKKGKLRFVRNCFP 86 Query: 49 PFFYPVDYGIIPRTWYD------------DDDPFDIMVIMREPTYPLTIIEARPIGLFKM 96 Y +YG P+TW D D+DP D+ I E +Y + + + +G+ + Sbjct: 87 HHGYIHNYGAFPQTWEDPNVTHPETKAKGDNDPLDVCEI-GERSYTGQVKQVKVLGVMAL 145 Query: 97 IDSGDKDYKVLAVPVEDPYFKDWKDIDDVPK---AFLDEIAHFFKRYKELQGK 146 +D G+ D+KV+ + + DP DI+DV K L +F+ YK GK Sbjct: 146 LDEGETDWKVIVIDINDPLAPKLNDIEDVEKHMPGLLRATNEWFRIYKIPDGK 198 >pir||T51225 related to INORGANIC PYROPHOSPHATASE [imported] - Neurospora crassa >gi|9453821|emb|CAB99389.1| (AL390354) related to INORGANIC PYROPHOSPHATASE [Neurospora crassa] Length = 387 Score = 67.9 bits (163), Expect = 7e-11 Identities = 56/212 (26%), Positives = 95/212 (44%), Gaps = 40/212 (18%) Query: 1 MNPFHDLEPGPNVPEVVYALI-EIPKGSRNKYELDKKTGLLKLDRVLYS-----PFF--- 51 ++PFHD+ + + VY +I EIP+ S+ K+E+ + L + + + S P F Sbjct: 68 ISPFHDIPLFHSRSQQVYNMIVEIPRWSQTKFEISRSLPLNPIVQDVLSARPNQPRFVPN 127 Query: 52 ------YPVDYGIIPRTWYD------------------DDDPFDIMVIMREPTYPLTIIE 87 YP +YG +P+TW D+DP D I Y + + Sbjct: 128 LFPYKGYPWNYGCLPQTWESPHYKGPGPDAEGAEGARGDNDPIDACEIGTRVAYTGEVKQ 187 Query: 88 ARPIGLFKMIDSGDKDYKVLAVPVEDPYFKDWKDIDDVPK---AFLDEIAHFFKRYKELQ 144 + +G+ ++D+G+ D+KVL V V D + DI DV + L+ +F Y + Sbjct: 188 VKVLGVLGLVDAGEMDWKVLVVDVRDKLAQKVDDIKDVERECPGLLEATRDWFTWYGVPE 247 Query: 145 GKE----IIVEGWEGAEAAKREILRAIELYKE 172 G++ + W+G E A I E++KE Sbjct: 248 GRKKNRFALGGEWKGREYAVGVIKECEEMWKE 279 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.320 0.145 0.443 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 76636179 Number of Sequences: 2977 Number of extensions: 3429378 Number of successful extensions: 6703 Number of sequences better than 1.0e-10: 97 Number of HSP's better than 0.0 without gapping: 74 Number of HSP's successfully gapped in prelim test: 23 Number of HSP's that attempted gapping in prelim test: 6529 Number of HSP's gapped (non-prelim): 97 length of query: 178 length of database: 189,106,746 effective HSP length: 49 effective length of query: 129 effective length of database: 159,780,883 effective search space: 20611733907 effective search space used: 20611733907 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.7 bits) S2: 162 (67.5 bits)