BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB1107 (PAB1107) DE:Transport protein
(425 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||C75019 transport protein PAB1107 - Pyrococcus abyssi (strai... 824 0.0
pir||F71205 hypothetical protein PH1912 - Pyrococcus horikoshii ... 727 0.0
gb|AAA62957.1| (U15181) hypothetical protein [Mycobacterium leprae] 331 1e-89
sp|O07186|YQ84_MYCTU HYPOTHETICAL 45.2 KDA PROTEIN RV2684 >gi|74... 331 1e-89
sp|P46838|AG45_MYCLE 46 KD MEMBRANE PROTEIN >gi|409174|gb|AAA994... 329 4e-89
sp|O07187|YQ85_MYCTU HYPOTHETICAL 45.2 KDA PROTEIN RV2685 >gi|74... 319 5e-86
pir||F72315 conserved hypothetical protein - Thermotoga maritima... 315 6e-85
dbj|BAB04950.1| (AP001511) unknown conserved protein in others [... 309 3e-83
gb|AAF97184.1|AF268611_7 (AF268611) permease [uncultured marine ... 301 9e-81
gb|AAF49861.1| (AE003539) CG11262 gene product [Drosophila melan... 232 5e-60
pir||G72300 conserved hypothetical protein - Thermotoga maritima... 228 1e-58
sp|P74635|Y753_SYNY3 HYPOTHETICAL 48.0 KD PROTEIN SLR0753 >gi|74... 219 4e-56
gb|AAD38580.1|AF145605_1 (AF145605) BcDNA.GH02636 [Drosophila me... 207 2e-52
gb|AAF50958.1| (AE003575) CG15624 gene product [Drosophila melan... 189 5e-47
gi|11499889 arsenite transport protein (arsB) [Archaeoglobus ful... 185 1e-45
gi|11230776 pink-eyed dilution protein [Mus musculus] >gi|200285... 176 4e-43
prf||1905395A pink eyed dilution gene [Homo sapiens] 173 4e-42
gi|4557811 P protein [Homo sapiens] >gi|548651|sp|Q04671|P_HUMAN... 172 6e-42
gb|AAC13784.1| (U19176) P protein [Homo sapiens] 172 6e-42
pir||A57173 oculocutaneous albinism II-related protein P - human... 171 2e-41
gb|AAF47636.1| (AE003474) CG13801 gene product [Drosophila melan... 159 6e-38
pir||B72758 hypothetical protein APE0055 - Aeropyrum pernix (str... 150 2e-35
gb|AAK40494.1| Arsenite transport protein (arsB) [Sulfolobus sol... 150 2e-35
gb|AAC13783.1| (U19176) P protein, truncated [Homo sapiens] 141 2e-32
gi|11433867 oculocutaneous albinism II (pink-eye dilution (murin... 141 2e-32
sp|Q01255|ARSB_STAXY ARSENICAL PUMP MEMBRANE PROTEIN >gi|282259|... 131 2e-29
sp|P30329|ARSB_STAAU ARSENICAL PUMP MEMBRANE PROTEIN >gi|282238|... 129 6e-29
emb|CAC11316.1| (AL445063) probable arsenical pump membrane prot... 126 5e-28
pir||G69779 arsenical pump membrane protein homolog ydfA - Bacil... 123 3e-27
gb|AAF69238.1|AF173880_1 (AF173880) arsenical membrane pump [Aci... 123 5e-27
dbj|BAB06718.1| (AP001517) arsenic efflux pump [Bacillus halodur... 122 1e-26
emb|CAB88405.1| (AJ288983) ArsB transmembrane efflux channel [Se... 118 2e-25
gb|AAF89641.1|AF168737_4 (AF168737) ArsB [Klebsiella oxytoca] 114 2e-24
dbj|BAA24823.1| (AB004659) ArsB [Acidiphilium multivorum] 112 7e-24
sp|P37310|ARSB_ECOLI ARSENICAL PUMP MEMBRANE PROTEIN >gi|516211|... 112 9e-24
pir||S47723 arsenite efflux pump (EC 1.-.-.-) - Escherichia coli... 112 9e-24
sp|P08691|ARB1_ECOLI ARSENICAL PUMP MEMBRANE PROTEIN >gi|78324|p... 109 5e-23
pir||G83361 ArsB protein PA2278 [imported] - Pseudomonas aerugin... 108 1e-22
sp|P52146|ARB2_ECOLI ARSENICAL PUMP MEMBRANE PROTEIN >gi|1061417... 106 4e-22
sp|Q57898|Y456_METJA HYPOTHETICAL PROTEIN MJ0456 >gi|2128333|pir... 102 8e-21
gi|10955595 arsenite pump transmembrane protein ArsB [Yersinia e... 102 1e-20
sp|Q57486|Y608_HAEIN HYPOTHETICAL PROTEIN HI0608 >gi|1075008|pir... 100 4e-20
pir||E81324 probable arsenical pump membrane protein Cj1187c [im... 100 4e-20
pir||H70606 probable arsenical pump membrane protein - Mycobacte... 100 5e-20
pir||B82510 transporter, NadC family VCA0025 [imported] - Vibrio... 100 5e-20
gb|AAC69643.1| (AF010234) ArsB [Pseudomonas aeruginosa] 99 1e-19
gb|AAC24385.1| (U89959) Hypothetical protein [Arabidopsis thaliana] 98 2e-19
sp|Q58086|Y672_METJA HYPOTHETICAL PROTEIN MJ0672 >gi|2129152|pir... 95 1e-18
pir||A75166 hypothetical protein PAB0325 - Pyrococcus abyssi (st... 94 3e-18
pir||C71131 hypothetical protein PH0816 - Pyrococcus horikoshii ... 92 1e-17
pir||F70302 transporter (Pho87 family) - Aquifex aeolicus >gi|29... 92 1e-17
sp|P75788|YBIR_ECOLI HYPOTHETICAL 41.2 KDA PROTEIN IM OMPX-MOEB ... 91 2e-17
pir||C69205 sodium/dicarboxylate or sulfate cotransporter - Meth... 85 2e-15
pir||G81156 transporter, NadC family NMB0792 [imported] - Neisse... 84 3e-15
pir||A81948 probable transmembrane transport protein NMA1003 [im... 84 3e-15
sp|P52137|YFJV_ECOLI PUTATIVE ARSENICAL PUMP MEMBRANE PROTEIN 81 3e-14
pir||B70069 arsenical pump membrane protein homolog ywrK - Bacil... 80 6e-14
gb|AAD12976.1| (AF078135) unknown [Leptospira borgpetersenii] 78 2e-13
pir||S43561 YCR37C homolog K08E5.2 - Caenorhabditis elegans 77 4e-13
sp|Q21339|YM22_CAEEL HYPOTHETICAL 58.7 KD PROTEIN K08E5.2 IN CHR... 77 4e-13
gb|AAD52193.1|AF144879_32 (AF144879) unknown [Leptospira interro... 73 5e-12
>pir||C75019 transport protein PAB1107 - Pyrococcus abyssi (strain Orsay)
>gi|5459107|emb|CAB50593.1| (AJ248288) Transport protein
[Pyrococcus abyssi]
Length = 425
Score = 824 bits (2106), Expect = 0.0
Identities = 425/425 (100%), Positives = 425/425 (100%)
Query: 1 MVSELEIIALGVFISVYAAIISEKIHRTVAAMLGASIMLFLKIVPWENIPEYLDLDTILL 60
MVSELEIIALGVFISVYAAIISEKIHRTVAAMLGASIMLFLKIVPWENIPEYLDLDTILL
Sbjct: 1 MVSELEIIALGVFISVYAAIISEKIHRTVAAMLGASIMLFLKIVPWENIPEYLDLDTILL 60
Query: 61 LAGMMVIVNISRESGLFEYIAIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLT 120
LAGMMVIVNISRESGLFEYIAIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLT
Sbjct: 61 LAGMMVIVNISRESGLFEYIAIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLT 120
Query: 121 PMLLYITRRMGVDPVPYLLAEIFASNIGGTATLIGDPPNIMIASAAKLSFNEFIMNMTPI 180
PMLLYITRRMGVDPVPYLLAEIFASNIGGTATLIGDPPNIMIASAAKLSFNEFIMNMTPI
Sbjct: 121 PMLLYITRRMGVDPVPYLLAEIFASNIGGTATLIGDPPNIMIASAAKLSFNEFIMNMTPI 180
Query: 181 AFLDLFIMVALIYLFYRREFKNVEYHVDGIMNLREEEAIRDKQLFRKSVVTIAFVVLAFF 240
AFLDLFIMVALIYLFYRREFKNVEYHVDGIMNLREEEAIRDKQLFRKSVVTIAFVVLAFF
Sbjct: 181 AFLDLFIMVALIYLFYRREFKNVEYHVDGIMNLREEEAIRDKQLFRKSVVTIAFVVLAFF 240
Query: 241 LHDTIGIEPAVVALTGASILLLWSRVPPEVALEKVEWATLFFFGGLFIIVGGLVETGLIE 300
LHDTIGIEPAVVALTGASILLLWSRVPPEVALEKVEWATLFFFGGLFIIVGGLVETGLIE
Sbjct: 241 LHDTIGIEPAVVALTGASILLLWSRVPPEVALEKVEWATLFFFGGLFIIVGGLVETGLIE 300
Query: 301 DVGKWIVSHISSENEAILMISWVSAFLSAIIDNIPFTATMIPLIKSMGGSINVYPLWWAL 360
DVGKWIVSHISSENEAILMISWVSAFLSAIIDNIPFTATMIPLIKSMGGSINVYPLWWAL
Sbjct: 301 DVGKWIVSHISSENEAILMISWVSAFLSAIIDNIPFTATMIPLIKSMGGSINVYPLWWAL 360
Query: 361 SLGACLGGNGTAIGASANVVVLGIAYREGIRITFIDFLKVGMIIMLLTVGAGSLVLIARY 420
SLGACLGGNGTAIGASANVVVLGIAYREGIRITFIDFLKVGMIIMLLTVGAGSLVLIARY
Sbjct: 361 SLGACLGGNGTAIGASANVVVLGIAYREGIRITFIDFLKVGMIIMLLTVGAGSLVLIARY 420
Query: 421 GGGIL 425
GGGIL
Sbjct: 421 GGGIL 425
>pir||F71205 hypothetical protein PH1912 - Pyrococcus horikoshii
>gi|3258354|dbj|BAA31037.1| (AP000007) 424aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 424
Score = 727 bits (1856), Expect = 0.0
Identities = 355/424 (83%), Positives = 400/424 (93%)
Query: 1 MVSELEIIALGVFISVYAAIISEKIHRTVAAMLGASIMLFLKIVPWENIPEYLDLDTILL 60
M+SE+EII LG+FI+ YA IISEKIHRTVAA+LGASIML L IVPWE +PEYLDLDTILL
Sbjct: 1 MISEVEIITLGIFIATYAVIISEKIHRTVAALLGASIMLVLNIVPWEKVPEYLDLDTILL 60
Query: 61 LAGMMVIVNISRESGLFEYIAIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLT 120
LAGMMV+VNIS+ESGLFEYIAIKVA++SKG+P+RVLLLFSVTTAVVSAFLDNVTTVLLLT
Sbjct: 61 LAGMMVVVNISKESGLFEYIAIKVAKVSKGNPIRVLLLFSVTTAVVSAFLDNVTTVLLLT 120
Query: 121 PMLLYITRRMGVDPVPYLLAEIFASNIGGTATLIGDPPNIMIASAAKLSFNEFIMNMTPI 180
PMLLYITRRMGV+PVPYLLAEIFASNIGGTATLIGDPPNIMI SAAKLSFN+FI+NM PI
Sbjct: 121 PMLLYITRRMGVNPVPYLLAEIFASNIGGTATLIGDPPNIMIGSAAKLSFNDFIVNMAPI 180
Query: 181 AFLDLFIMVALIYLFYRREFKNVEYHVDGIMNLREEEAIRDKQLFRKSVVTIAFVVLAFF 240
+F+DLFIM+AL+Y+ Y++EF V+Y++DGIMNLREE+AI+D++LF+KSV+TI +++AFF
Sbjct: 181 SFMDLFIMIALVYILYKKEFSRVKYNLDGIMNLREEDAIKDRELFKKSVITIGLIIVAFF 240
Query: 241 LHDTIGIEPAVVALTGASILLLWSRVPPEVALEKVEWATLFFFGGLFIIVGGLVETGLIE 300
HD +GIEPAVVALTGA+ILLLWSRV PEVALEKVEWATLFFFGGLFIIVGGLVETGLI+
Sbjct: 241 FHDALGIEPAVVALTGATILLLWSRVSPEVALEKVEWATLFFFGGLFIIVGGLVETGLID 300
Query: 301 DVGKWIVSHISSENEAILMISWVSAFLSAIIDNIPFTATMIPLIKSMGGSINVYPLWWAL 360
+ GKWIV HI+SENEAIL+ISW+SAF SAIIDNIPFTATMIPLIKSM GSIN+YPLWWAL
Sbjct: 301 EAGKWIVRHITSENEAILLISWISAFSSAIIDNIPFTATMIPLIKSMAGSINIYPLWWAL 360
Query: 361 SLGACLGGNGTAIGASANVVVLGIAYREGIRITFIDFLKVGMIIMLLTVGAGSLVLIARY 420
SLGACLGGNGTAIGASANVVVLGIAYREGIRITF DFLKVGM +M+ +V AGSLVLIARY
Sbjct: 361 SLGACLGGNGTAIGASANVVVLGIAYREGIRITFKDFLKVGMAVMISSVAAGSLVLIARY 420
Query: 421 GGGI 424
GGGI
Sbjct: 421 GGGI 424
>gb|AAA62957.1| (U15181) hypothetical protein [Mycobacterium leprae]
Length = 429
Score = 331 bits (839), Expect = 1e-89
Identities = 179/425 (42%), Positives = 271/425 (63%), Gaps = 9/425 (2%)
Query: 5 LEIIALGVFISVYAAIISEKIHRTVAAMLGASIMLFLKIVPWENI----PEYLDLDTILL 60
+ +IA+ VFI YA I S+++++T+AA+ GA+I++ L I+ E++ +D + I L
Sbjct: 1 MSVIAITVFIVTYALIASDRVNKTLAALTGAAIVVTLPIINSEDVFYSHETGIDWEVIFL 60
Query: 61 LAGMMVIVNISRESGLFEYIAIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLT 120
L MM+IV++ R++G+FEY+AI A+ S G P+R+LLL + A+ SA LDNVTTVLL+
Sbjct: 61 LLSMMIIVSVLRQTGVFEYVAIWTAKRSHGSPLRILLLLVLVMALGSALLDNVTTVLLIA 120
Query: 121 PMLLYITRRMGVDPVPYLLAEIFASNIGGTATLIGDPPNIMIASAAKLSFNEFIMNMTPI 180
P+ L + R+ ++ P+L+AE+FASNIGG ATL+GDPPNI+IAS A SFN+F++++TPI
Sbjct: 121 PVTLLVCERLTINAAPFLMAEVFASNIGGAATLVGDPPNIIIASRAGFSFNDFLIHLTPI 180
Query: 181 AFLDLFIMVALIYLFYRREFKNVEYHVDGIMNLREEEAIRDKQLFRKSVVTIAFVVLAFF 240
+ ++ AL+ +R F V IM+L E EAIRD+ L K V + V +AF
Sbjct: 181 VIIVTVVLSALLPRLFRGAFAVDPERVADIMSLNEREAIRDRWLLIKCGVVLLLVFVAFI 240
Query: 241 LHDTIGIEPAVVALTGASILLLWSRVPPEVALEKVEWATLFFFGGLFIIVGGLVETGLIE 300
H + P++V + GA IL++ S++ L V+W TL FF GLFI+VG LV+T ++
Sbjct: 241 AHPVLHTGPSLVGMLGAGILIVISKLERSDYLSSVKWETLLFFAGLFIMVGALVKTDVVN 300
Query: 301 DVGKWIVSHISS-ENEAILMISWVSAFLSAIIDNIPFTATMIP----LIKSMGGSINVYP 355
+ + + E +++ VS +S+IIDNIP+ ATM P L+ SM +
Sbjct: 301 QLARATTTLTGGHELLTVVLTLGVSTLVSSIIDNIPYVATMTPIVSELVASMPDQSHTDI 360
Query: 356 LWWALSLGACLGGNGTAIGASANVVVLGIAYREGIRITFIDFLKVGMIIMLLTVGAGSLV 415
LWWAL+LGA GGN TA+GASANVV+L IA G I+F +F + G+ + ++++ +
Sbjct: 361 LWWALALGADFGGNLTAVGASANVVMLEIAKSAGTPISFWEFTRKGIAVTVISIALAGIY 420
Query: 416 LIARY 420
L RY
Sbjct: 421 LWLRY 425
>sp|O07186|YQ84_MYCTU HYPOTHETICAL 45.2 KDA PROTEIN RV2684 >gi|7477889|pir||G70528
probable arsA protein - Mycobacterium tuberculosis
(strain H37RV) >gi|2181975|emb|CAB09495.1| (Z96072) arsA
[Mycobacterium tuberculosis]
Length = 429
Score = 331 bits (839), Expect = 1e-89
Identities = 176/429 (41%), Positives = 275/429 (64%), Gaps = 18/429 (4%)
Query: 5 LEIIALGVFISVYAAIISEKIHRTVAAMLGASIMLFLKIVPWENI----PEYLDLDTILL 60
+ ++A+ +F++ Y I S+++++T+ A+ GA+ ++ L ++ +I +D D I L
Sbjct: 1 MSVVAVTIFVAAYVLIASDRVNKTMVALTGAAAVVVLPVITSHDIFYSHDTGIDWDVIFL 60
Query: 61 LAGMMVIVNISRESGLFEYIAIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLT 120
L GMM+IV + R++G+FEY AI A+ ++G P+R+++L + +A+ SA LDNVTTVLL+
Sbjct: 61 LVGMMIIVGVLRQTGVFEYTAIWAAKRARGSPLRIMILLVLVSALASALLDNVTTVLLIA 120
Query: 121 PMLLYITRRMGVDPVPYLLAEIFASNIGGTATLIGDPPNIMIASAAKLSFNEFIMNMTPI 180
P+ L + R+ ++ +L+AE+FASNIGG ATL+GDPPNI++AS A L+FN+F++++TP+
Sbjct: 121 PVTLLVCDRLNINTTSFLMAEVFASNIGGAATLVGDPPNIIVASRAGLTFNDFMLHLTPL 180
Query: 181 AFLDLFIMVALIYLFYRREFKNVEYHVD---GIMNLREEEAIRDKQLFRKSVVTIAFVVL 237
+ L ++A++ R F ++ D +M L E EAIRD+ L K + V
Sbjct: 181 VVIVLIALIAVL----PRLFGSITVEADRIADVMALDEGEAIRDRGLLVKCGAVLVLVFA 236
Query: 238 AFFLHDTIGIEPAVVALTGASILLLWSRVPPEVALEKVEWATLFFFGGLFIIVGGLVETG 297
AF H + I+P++VAL GA +L++ S + L VEW TL FF GLFI+VG LV+TG
Sbjct: 237 AFVAHPVLHIQPSLVALLGAGMLIVVSGLTRSEYLSSVEWDTLLFFAGLFIMVGALVKTG 296
Query: 298 LIEDVGKWIVSHISSEN--EAILMISWVSAFLSAIIDNIPFTATMIPLIKS----MGGSI 351
++ D+ + + ++ N +I VSA +S IIDNIP+ ATM PL+ MGG
Sbjct: 297 VVNDLAR-AATQLTGGNIVATAFLILGVSAPISGIIDNIPYVATMTPLVAELVAVMGGQP 355
Query: 352 NVYPLWWALSLGACLGGNGTAIGASANVVVLGIAYREGIRITFIDFLKVGMIIMLLTVGA 411
+ WWAL+LGA GGN TAIGASANVV+LGIA R G I+F +F + G ++ +++
Sbjct: 356 STDTPWWALALGADFGGNLTAIGASANVVMLGIARRAGAPISFWEFTRKGAVVTAVSIAL 415
Query: 412 GSLVLIARY 420
++ L RY
Sbjct: 416 AAIYLWLRY 424
>sp|P46838|AG45_MYCLE 46 KD MEMBRANE PROTEIN >gi|409174|gb|AAA99493.1| (L10660) 46 kDa
protein [Mycobacterium leprae]
Length = 429
Score = 329 bits (834), Expect = 4e-89
Identities = 178/425 (41%), Positives = 270/425 (62%), Gaps = 9/425 (2%)
Query: 5 LEIIALGVFISVYAAIISEKIHRTVAAMLGASIMLFLKIVPWENI----PEYLDLDTILL 60
+ +IA+ VFI YA I S+++++T+AA+ GA+I++ L I+ E++ +D + I L
Sbjct: 1 MSVIAITVFIVTYALIASDRVNKTLAALTGAAIVVTLPIINSEDVFYSHETGIDWEVIFL 60
Query: 61 LAGMMVIVNISRESGLFEYIAIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLT 120
L MM+IV++ R++G+FEY+AI A+ S G P+R+LLL + A+ SA LDNVTTVLL+
Sbjct: 61 LLSMMIIVSVLRQTGVFEYVAIWTAKRSHGSPLRILLLLVLVMALGSALLDNVTTVLLIA 120
Query: 121 PMLLYITRRMGVDPVPYLLAEIFASNIGGTATLIGDPPNIMIASAAKLSFNEFIMNMTPI 180
P+ L + R+ ++ P+L+AE+FASNIGG TL+GDPPNI+IAS A SFN+F++++TPI
Sbjct: 121 PVTLLVCERLTINAAPFLMAEVFASNIGGARTLVGDPPNIIIASRAGFSFNDFLIHLTPI 180
Query: 181 AFLDLFIMVALIYLFYRREFKNVEYHVDGIMNLREEEAIRDKQLFRKSVVTIAFVVLAFF 240
+ ++ AL+ +R F V IM+L E EAIRD+ L K V + V +AF
Sbjct: 181 VIIVTVVLSALLPRLFRGAFAVDPERVADIMSLNEREAIRDRWLLIKCGVVLLLVFVAFI 240
Query: 241 LHDTIGIEPAVVALTGASILLLWSRVPPEVALEKVEWATLFFFGGLFIIVGGLVETGLIE 300
H + P++V + GA IL++ S++ L V+W TL FF GLFI+VG LV+T ++
Sbjct: 241 AHPVLHTGPSLVGMLGAGILIVISKLERSDYLSSVKWETLLFFAGLFIMVGALVKTDVVN 300
Query: 301 DVGKWIVSHISS-ENEAILMISWVSAFLSAIIDNIPFTATMIP----LIKSMGGSINVYP 355
+ + + E +++ VS +S+IIDNIP+ ATM P L+ SM +
Sbjct: 301 QLARATTTLTGGHELLTVVLTLGVSTLVSSIIDNIPYVATMTPIVSELVASMPDQSHTDI 360
Query: 356 LWWALSLGACLGGNGTAIGASANVVVLGIAYREGIRITFIDFLKVGMIIMLLTVGAGSLV 415
LWWAL+LGA GGN TA+GASANVV+L IA G I+F +F + G+ + ++++ +
Sbjct: 361 LWWALALGADFGGNLTAVGASANVVMLEIAKSAGTPISFWEFTRKGIAVTVISIALAGIY 420
Query: 416 LIARY 420
L RY
Sbjct: 421 LWLRY 425
>sp|O07187|YQ85_MYCTU HYPOTHETICAL 45.2 KDA PROTEIN RV2685 >gi|7477890|pir||H70528
probable arsB protein - Mycobacterium tuberculosis
(strain H37RV) >gi|2181976|emb|CAB09476.1| (Z96072) arsB
[Mycobacterium tuberculosis]
Length = 428
Score = 319 bits (808), Expect = 5e-86
Identities = 179/428 (41%), Positives = 271/428 (62%), Gaps = 16/428 (3%)
Query: 5 LEIIALGVFISVYAAIISEKIHRTVAAMLGASIMLFLKIVPWENI----PEYLDLDTILL 60
+ IIA+ VF++ YA I S+++ +T A+ A+IM+ IV +++ +D D I L
Sbjct: 1 MSIIAITVFVAGYALIASDRVSKTRVALTCAAIMVGAGIVGSDDVFYSHEAGIDWDVIFL 60
Query: 61 LAGMMVIVNISRESGLFEYIAIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLT 120
L GMM+IV++ R +G+FEY+AI + + P+R+++L + TA+ SA LDNVTTVLL+
Sbjct: 61 LLGMMIIVSVLRHTGVFEYVAIWAVKRANAAPLRIMILLVLVTALGSALLDNVTTVLLIA 120
Query: 121 PMLLYITRRMGVDPVPYLLAEIFASNIGGTATLIGDPPNIMIASAAKLSFNEFIMNMTPI 180
P+ L + R+GV+ P+L+AE+FASN+GG ATL+GDPPNI+IAS A L+FN+F+++M P
Sbjct: 121 PVTLLVCDRLGVNSTPFLVAEVFASNVGGAATLVGDPPNIIIASRAGLTFNDFLIHMAPA 180
Query: 181 AFLDLFIMVALIYL--FYRREFKNVEYHVDGIMNLREEEAIRDKQLFRKSVVTIAFVVLA 238
L +M+ALI L + V +++L E EAI D+ L K V + V A
Sbjct: 181 V---LVVMIALIGLLPWLLGSVTAEPDRVADVLSLNEREAIHDRGLLIKCGVVLVLVFAA 237
Query: 239 FFLHDTIGIEPAVVALTGASILLLWSRVPPEVALEKVEWATLFFFGGLFIIVGGLVETGL 298
F H + I+P++VAL GA +L+ +S + L VEW TL FF GLF++VG LV+TG+
Sbjct: 238 FIAHPVLHIQPSLVALLGAGVLVRFSGLERSDYLSSVEWDTLLFFAGLFVMVGALVKTGV 297
Query: 299 IEDVGKWIVSHISSENEAIL--MISWVSAFLSAIIDNIPFTATMIP----LIKSMGGSIN 352
+E + + + ++ NE + +I +SA +S IIDNIP+ ATM P L+ +M G ++
Sbjct: 298 VEQLAR-AATELTGGNELLTVGLILGISAPVSGIIDNIPYVATMTPIVTELVAAMPGHVH 356
Query: 353 VYPLWWALSLGACLGGNGTAIGASANVVVLGIAYREGIRITFIDFLKVGMIIMLLTVGAG 412
WWAL+L A GGN TA+ ASANVV+LGIA R G I+F F + G ++ +++
Sbjct: 357 PDTFWWALALSADFGGNLTAVAASANVVMLGIARRSGTPISFWKFTRKGAVVTAVSLVLS 416
Query: 413 SLVLIARY 420
++ L RY
Sbjct: 417 AVYLWLRY 424
>pir||F72315 conserved hypothetical protein - Thermotoga maritima (strain MSB8)
>gi|4981472|gb|AAD36015.1|AE001757_8 (AE001757)
conserved hypothetical protein [Thermotoga maritima]
Length = 425
Score = 315 bits (799), Expect = 6e-85
Identities = 176/424 (41%), Positives = 264/424 (61%), Gaps = 14/424 (3%)
Query: 7 IIALGVFISVYAAIISEKIHRTVAAMLGASIMLFLKIV-PWENIPEYLDLDTILLLAGMM 65
+++L +FI VY II EK HR V MLG S LFL P E + Y+D +TI LL GMM
Sbjct: 6 VVSLLIFIIVYLFIILEKHHRAVITMLGGSAALFLVFKDPIEALVRYVDFNTIFLLIGMM 65
Query: 66 VIVNISRESGLFEYIAIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLTPMLLY 125
+ V++++ SGLF ++ + ++S G+ + + A++S+FLDNVTT+L+ P+ L
Sbjct: 66 IFVSVTKRSGLFHFLGLYSVKLSGGNVFLFFIAINTLVALLSSFLDNVTTILVFVPVTLV 125
Query: 126 ITRRMGVDPVPYLLAEIFASNIGGTATLIGDPPNIMIASAAKLSFNEFIMNMTPIAFLDL 185
+ + +DPVP++++EI +SNIGGTAT+IGDPPNIMIASAAKL F +F++N+ P A L L
Sbjct: 126 VCDTVDLDPVPFVISEIISSNIGGTATMIGDPPNIMIASAAKLHFLDFVVNVAPAAVLTL 185
Query: 186 FIMVALIYLFYRRE-FKNVEYHVDGIMNLREEEAIRDKQLFRKSVVTIAFVVLAFFLHDT 244
+ + + YRR F+ + V+ + + AI DK+LF S++ V++ F L
Sbjct: 186 IVTLIFLSAVYRRVIFRKIP--VEVVKDFDPRRAIVDKKLFYLSIILTLVVLVLFSLQKP 243
Query: 245 IGIEPAVVA-LTGASILLLWSRVPPEVALEKVEWATLFFFGGLFIIVGGLVETGLIEDVG 303
+G+E VA L G L + E +++EW +FFF GLF++VG L E G++E +
Sbjct: 244 LGLESFEVALLAGFLSLAFLKKKDIEDVFKEIEWGVIFFFIGLFLVVGALEEAGVLERIS 303
Query: 304 KWIVSHISSENEAILM-ISWVSAFLSAIIDNIPFTATMIPLIKSMG-----GSINVYPLW 357
+ ++ + E+ L+ + +S SA +DNIPFTATMIP+IK + ++ PLW
Sbjct: 304 ELVIRLSKGKMESTLISVLGISGLSSAFVDNIPFTATMIPVIKKLAVLAPETFSDLRPLW 363
Query: 358 WALSLGACLGGNGTAIGASANVVVLG-IAYREGIRITFIDFLKVGMIIMLLTVGAGSLVL 416
WALSLGAC GGNGT IGASANVV IA R+ ITF ++ K+G +++L++ + L
Sbjct: 364 WALSLGACFGGNGTLIGASANVVGTSLIADRK--HITFWEYFKIGFPVLILSLLVSGVYL 421
Query: 417 IARY 420
+ RY
Sbjct: 422 LIRY 425
>dbj|BAB04950.1| (AP001511) unknown conserved protein in others [Bacillus
halodurans]
Length = 428
Score = 309 bits (784), Expect = 3e-83
Identities = 166/420 (39%), Positives = 264/420 (62%), Gaps = 7/420 (1%)
Query: 8 IALGVFISVYAAIISEKIHRTVAAMLGASIMLFLKIVPWEN-IPEYLDLDTILLLAGMMV 66
+AL +F+ Y I++E +R V A LG +MLF+ I P + +Y+D TI LL MM+
Sbjct: 5 LALVIFVICYLLIMAETFNRAVVACLGGVLMLFVGIYPLDAAFLQYIDWHTITLLLSMMI 64
Query: 67 IVNISRESGLFEYIAIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLTPMLLYI 126
+V+I+ +SG FEY+AI++A+ G P+ +L++ + TA+ SAFL+NVT VLL+ P++L +
Sbjct: 65 LVSITSQSGFFEYMAIRLAQKVDGRPIPLLIVVAGITAIGSAFLNNVTMVLLIVPIVLTL 124
Query: 127 TRRMGVDPVPYLLAEIFASNIGGTATLIGDPPNIMIASA-AKLSFNEFIMNMTPIAFLDL 185
T + ++ VP+LL + ASNIGGTATLIGDPPN+MI A A LSFN+F++++ PI +
Sbjct: 125 TNLLKLNAVPFLLTLVMASNIGGTATLIGDPPNLMIGQAVAHLSFNDFLLHLGPIVAVIF 184
Query: 186 FIMVALIYLFYRREFKNVEYHVDGIMNLREEEAIRDKQLFRKSVVTIAFVVLAFFLHDTI 245
F+++ + L+YRR+ + + ++++ L KS+ + + F + +
Sbjct: 185 FVVLIGLILYYRRQLSVTAEDRSRLRGVDPTSYLKNRPLLIKSMTVLTLTTIGFTIQPFL 244
Query: 246 GIEPAVVALTGASILLLWSRVPPEV--ALEKVEWATLFFFGGLFIIVGGLVETGLIEDVG 303
+E +A+ GA +L+L ++ ++ VEW TLFFF GLF++VGG+ E G+I+++
Sbjct: 245 PVELTSIAMAGALLLMLITQNEQDMEGVFRSVEWVTLFFFIGLFMLVGGIKEVGIIDEIA 304
Query: 304 KWIVSHISSE-NEAILMISWVSAFLSAIIDNIPFTATMIPLIKSMG--GSINVYPLWWAL 360
K I+ + + + L I W S LS +DNIPF A MIP+I G + PLWW+L
Sbjct: 305 KAIIYYTEGDIPKTSLFILWGSGILSGFVDNIPFVAAMIPVILEFQEYGVGELDPLWWSL 364
Query: 361 SLGACLGGNGTAIGASANVVVLGIAYREGIRITFIDFLKVGMIIMLLTVGAGSLVLIARY 420
+LGACLGGN T IGA+ANV+V G+A + ++++FLKVG + L++ ++ L RY
Sbjct: 365 ALGACLGGNATVIGATANVIVAGLAVQAKQSFSYLEFLKVGAPVALVSFLLCTVYLYIRY 424
>gb|AAF97184.1|AF268611_7 (AF268611) permease [uncultured marine group II euryarchaeote
37F11]
Length = 573
Score = 301 bits (763), Expect = 9e-81
Identities = 180/448 (40%), Positives = 261/448 (58%), Gaps = 37/448 (8%)
Query: 8 IALGVFISVYAAIISEKIHRTVAAMLGASIMLFL-------KIVPWENIPEYLDLDTILL 60
+ LG+ + VYA II+E +HRT+AA LG + + + + + + +D +TI L
Sbjct: 59 VGLGILLFVYALIITEVVHRTLAATLGGLLAVIALNHYSVEEALSLKAVTTMIDWETIGL 118
Query: 61 LAGMMVIVNISRESGLFEYIAIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLT 120
L GMMV+V I +G+FE+ A++ + S G+ ++++ TAV+SAFLDNVTT+LLLT
Sbjct: 119 LLGMMVMVGIISHTGVFEWFAVQAYKKSGGEIWTLVVILCSVTAVLSAFLDNVTTMLLLT 178
Query: 121 PMLLYITRRMGVDPVPYLLAEIFASNIGGTATLIGDPPNIMIASAAK------------- 167
P+ + I + + + P+P L++E+ SNIGG AT+IGDPPNIMI SA
Sbjct: 179 PVTIKIAQVLDLKPIPILISEVLFSNIGGAATMIGDPPNIMIGSAMSPDAISGNKDPNIA 238
Query: 168 ------LSFNEFIMNMTPIAFLDLFIMVALIYLFYRREFKNVEYHVDGIMNLREEEAIRD 221
++FN+FI M P + + LI Y+ EF I L + AI+D
Sbjct: 239 NLASDGVTFNDFITEMAPGILMTIVPSFMLIRWLYKDEFSGRRDR--DITELERQYAIKD 296
Query: 222 KQLFRKSVVTIAFVVLAFFLHDTIGIEPAVVALTGASILLL-WSRVPPEVALEKVEWATL 280
+ + S + V+L FFLH I + + VAL+GA ++LL +R E LE VEW TL
Sbjct: 297 IKGLKVSGAILTLVILGFFLHPVIHLAVSWVALSGALVMLLATNRHELEEPLEHVEWTTL 356
Query: 281 FFFGGLFIIVGGLVETGLIEDVGKWIVSHISSENE------AILMISWVSAFLSAIIDNI 334
FF GLF++V L G+I+ +G+++ I + AIL+I WVSA SA IDNI
Sbjct: 357 LFFAGLFVLVHSLQYMGVIDYIGEYVEKAIKFFPDDYRLAAAILIILWVSAIASAFIDNI 416
Query: 335 PFTATMIPLIKSMGGSIN--VYPLWWALSLGACLGGNGTAIGASANVVVLGIAYREGIRI 392
P+TATMIP++ S+ +N + PL WAL+ GACLGGNGT IGASANVV G++ G I
Sbjct: 417 PYTATMIPIVLSLAFELNLPLNPLIWALAFGACLGGNGTLIGASANVVTAGMSEEAGYPI 476
Query: 393 TFIDFLKVGMIIMLLTVGAGSLVLIARY 420
+F +F + G +MLL+ S +I Y
Sbjct: 477 SFNEFFRAGFPVMLLSTFIVSFYMILVY 504
>gb|AAF49861.1| (AE003539) CG11262 gene product [Drosophila melanogaster]
Length = 666
Score = 232 bits (586), Expect = 5e-60
Identities = 157/473 (33%), Positives = 242/473 (50%), Gaps = 67/473 (14%)
Query: 12 VFISVYAAIISEKIHRTVAAML----GASIMLFLKIVPW-ENIPEYLDLDTILLLAGMMV 66
+ I Y I+ E RT AA++ G +I+ L P E I ++D +T++LL GMM+
Sbjct: 183 LLIGFYILIVFELTDRTFAALMMATTGIAILTALGNRPTLETIISWIDFETLILLLGMMI 242
Query: 67 IVNISRESGLFEYIAIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLTPMLLYI 126
+V I E+G+F+++A+ RISKG+P +LLL S TA++S LDNVT +LL+ P+ + +
Sbjct: 243 LVAIMSETGVFDWMAVLAYRISKGNPWPMLLLLSSITAIMSCMLDNVTMLLLMAPIAIRL 302
Query: 127 TRRMGVDPVPYLLAEIFASNIGGTATLIGDPPNIMIAS-----AAKLSFNEFIMNMTPIA 181
M V L+ + SNIGGT T +GDPPN++IA+ +A + F +F ++M P
Sbjct: 303 CEAMAVQTPLVLIVVVMYSNIGGTLTPVGDPPNVIIATNSEVISAGVDFLDFTIHMLPGV 362
Query: 182 FLDLFIMVALIYLFYRREF----------------------------------------- 200
L A++Y+ R+
Sbjct: 363 LLAAVAGYAVMYVTMRKSLFKLEEQQLELAAERENSRRRSSADITARAEEMRIRQPTGRQ 422
Query: 201 --KNVEYHVDGIMNLREEEAIRDKQLFRKSVVTIAFVVLAFFLHDTIGIEPAV---VALT 255
K E + + +L IRDK L K + T+ FV++ F LH + A VA+
Sbjct: 423 LLKPAENYFQTLAHLEAHHRIRDKTLLIKCLFTLCFVIIFFLLHSLPFMHGATLGWVAIL 482
Query: 256 GASILLLWSRVPP-EVALEKVEWATLFFFGGLFIIVGGLVETGLIEDVGKWIVSHISSEN 314
A +LL+ +++ E L++VEW+ L F LF++ + + G I + V I S
Sbjct: 483 AAFLLLILAKMNDIEAILDQVEWSALLFLAALFVLTEAVDKLGFIRWLCDLTVKVIMSVE 542
Query: 315 E------AILMISWVSAFLSAIIDNIPFTATM----IPLIKSMGGSINVYPLWWALSLGA 364
E AIL+I W+SA L+A + N+P T + I L ++ S+ + PL WALS GA
Sbjct: 543 ERYQTTVAILIIIWMSAILAAFVGNVPVTTMLLRLNIELHRNDAISVPLTPLIWALSYGA 602
Query: 365 CLGGNGTAIGASANVVVLGIAYREGIRITFIDFLKVGMIIMLLTVGAGSLVLI 417
C GGNGT IGASANVV IA + G +I+F+ F G +ML ++ ++ L+
Sbjct: 603 CFGGNGTLIGASANVVAAAIAQQYGYKISFVQFFIYGFPMMLTSIFLATVYLL 655
>pir||G72300 conserved hypothetical protein - Thermotoga maritima (strain MSB8)
>gi|4981587|gb|AAD36122.1|AE001765_1 (AE001765)
conserved hypothetical protein [Thermotoga maritima]
Length = 421
Score = 228 bits (575), Expect = 1e-58
Identities = 135/398 (33%), Positives = 224/398 (55%), Gaps = 5/398 (1%)
Query: 14 ISVYAAIISEKIHRTVAAMLGASIMLFLKIVPW---ENIPEYLDLDTILLLAGMMVIVNI 70
I Y II KI ++V +L A +++ +K+V +NI E +D +T+ LL GMM+IV+I
Sbjct: 12 ILAYYFIIFGKIAKSVVTLLIALVLMAIKVVEGLDLKNIGEVVDFNTLGLLLGMMIIVHI 71
Query: 71 SRESGLFEYIAIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLTPMLLYITRRM 130
+ +G FEY+AI +IS+G + V TAV SAFLDN+ T++L++P+L I M
Sbjct: 72 LKGTGFFEYLAISAIKISRGRFWLLFAFLMVLTAVTSAFLDNLITIILVSPILFLILDTM 131
Query: 131 GVDPVPYLLAEIFASNIGGTATLIGDPPNIMIASAAKLSFNEFIMNMTPIAFLDLFIMVA 190
V+PVP+ L IF NIGG +TLIG P NI++ S + LSFN+F+ NM + L +F++V
Sbjct: 132 EVNPVPFFLFTIFIDNIGGMSTLIGSPLNIVLGSISGLSFNDFLKNMGLVTVL-MFVVVF 190
Query: 191 LIYLFYRREFKNVEYHVDGIMNLREEEAIRDKQLFRKSVVTIAFVVLAFFLHDTIGIEPA 250
++ Y R + + ++++ + +I D + +KS+ ++ F LH + +E +
Sbjct: 191 FLFKRYVRIDEKAFEKLRNLLSVDPKRSITDPVVLKKSLFVFLSTLVLFGLHSFVEVELS 250
Query: 251 VVALTGASILLLWSRVPPEVALEKVEWATLFFFGGLFIIVGGLVETGLIEDVGKWIVSHI 310
++AL A LLL E E ++W TLFF+ GLFII L + G++E + ++ +
Sbjct: 251 LIALIAACALLLMLGKNFEKVSEGIDWDTLFFYTGLFIISYSLEQIGVMEVIASFLKALS 310
Query: 311 SSENEAILMISWVSAFLSAIIDNIPFTATMIPLIKSMGGSINVYPLWWALSLGACLGGNG 370
+ + ++W+S +A + +P T + P +K + LWW ++GA LG N
Sbjct: 311 FNRFLFVATVTWISILSTAFLSAVPATLIIAPTLKILVSQGFPASLWWVYAVGANLGTNL 370
Query: 371 TAIGASANVVVLGIAYR-EGIRITFIDFLKVGMIIMLL 407
T +GA N+V L + + ++F +F KV M +
Sbjct: 371 TPLGAVQNIVGLSLLEKYTKHTVSFKEFFKVAWSFMFI 408
>sp|P74635|Y753_SYNY3 HYPOTHETICAL 48.0 KD PROTEIN SLR0753 >gi|7469763|pir||S76839
hypothetical protein - Synechocystis sp. (strain PCC
6803) >gi|1653841|dbj|BAA18751.1| (D90917) P protein
[Synechocystis sp.]
Length = 449
Score = 219 bits (553), Expect = 4e-56
Identities = 137/443 (30%), Positives = 244/443 (54%), Gaps = 34/443 (7%)
Query: 1 MVSELE-IIALGVFISVYAAIISEKIHRTVAAMLGASIMLFLKIVPWENIPEYLDLD--T 57
MV+ L + +LGVF+ V I+SEKIH T+AA LGA I++F ++ + +Y+ T
Sbjct: 1 MVANLPALFSLGVFVGVILLIMSEKIHLTIAAFLGALILVFTHVITLKEGIDYISQSYAT 60
Query: 58 ILLLAGMMVIVNISRESGLFEYIAIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTVL 117
+ L G+MV+V + +FEY+A ++ ++KG ++L T + A L N TTV+
Sbjct: 61 LALFFGVMVLVRSFEPTKIFEYLATQMVLLAKGSGKLLMLGVIAITTPICAVLPNATTVM 120
Query: 118 LLTPMLLYITRRMGVDPVPYLLAEIFASNIGGTATLIGDPPNIMIASAAKLSFNEFIMNM 177
LL P++ + + +GVD VP L+ +F +N G TL+GDP ++ A +SFN+++ +
Sbjct: 121 LLAPLIPPLAQEIGVDFVPILILMVFVANSAGLLTLVGDPATFIVGDAINISFNDYLFKL 180
Query: 178 TPIAFLDLFIMVALIYLFYRREFKNVEYHVDGIMNLREEEAIRDKQLFRKSVVTIAFVVL 237
+ + L + +V + +R +++ H++ + I ++ V I V++
Sbjct: 181 SFMGVLAIVSIVVITPFLFRHIWRSRFTHLEDL----PHPQINHPKVLMAGGVIITLVLI 236
Query: 238 AFFLHDT--IGIEPAVVALTGASI-LLLWSRVPPEVA---LEKVEWATLFFFGGLFIIVG 291
F + ++ + I PA VAL GA + LLL S+ + L V+W+TL FF +F+I+G
Sbjct: 237 FFVIGESLPVPIPPASVALMGACLALLLASQSKIDTVHNILRDVDWSTLIFFMSIFVIIG 296
Query: 292 GLVETGLIEDVGKWIVSHISSENEAI--LMISWVSAFLSAIIDNIPFTATMIPLIKS--- 346
L +TG+ + + +++ + +N A +++ + LS+++ NIP M+PL+K
Sbjct: 297 SLEKTGVTASLAQ-LLAVVVGQNIAFGAIVLVFTVGLLSSVVPNIPLVVAMVPLLKQYVV 355
Query: 347 ---------MGGSIN------VYPLWWALSLGACLGGNGTAIGASANVVVLGIAYREGIR 391
+G + + V PL++A+ GA LGGNGT +GAS+N+V GI+ + G
Sbjct: 356 NIGFAGPEILGANFDGQLPAEVLPLFYAMMFGATLGGNGTLVGASSNIVAAGISEQHGRP 415
Query: 392 ITFIDFLKVGMIIMLLTVGAGSL 414
I+F FL+ G+ +M + + +L
Sbjct: 416 ISFHRFLRYGLPVMAVQLVVAAL 438
>gb|AAD38580.1|AF145605_1 (AF145605) BcDNA.GH02636 [Drosophila melanogaster]
>gi|7295655|gb|AAF50961.1| (AE003575) BcDNA:GH02636 gene
product [Drosophila melanogaster]
Length = 803
Score = 207 bits (522), Expect = 2e-52
Identities = 159/504 (31%), Positives = 247/504 (48%), Gaps = 101/504 (20%)
Query: 7 IIALGVFISVYAAIISEKIHRTVAAMLGAS----IMLFLKIVP-WENIPEYLDLDTILLL 61
I A V +Y II E ++RT AA++ ++ I+ L P I ++D++T+LLL
Sbjct: 300 IYAAAVLCGLYVMIIWEIVNRTFAAIIASTLSVGILAALNSRPSMATIMGWIDVETLLLL 359
Query: 62 AGMMVIVNISRESGLFEYIAIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLTP 121
GMM++V I E+G+F+Y+A+ +I+ G ++ + TAV+S+FLDNVTTVLL+TP
Sbjct: 360 FGMMILVAILSETGVFDYLAVYAYKITNGHVWPLINCLCLFTAVLSSFLDNVTTVLLMTP 419
Query: 122 MLLYITRRMGVDPVPYLLAEIFASNIGGTATLIGDPPNIMIASAAKLS-----FNEFIMN 176
+ + + M ++PVP L+ + SNIGG T +GDPPN++IAS + +S F F ++
Sbjct: 420 VTIRLCEVMCLNPVPILMCMVIYSNIGGALTPVGDPPNVIIASNSYISKNGVNFAVFTLH 479
Query: 177 MTPIAFLDLFIMVALIYLFYRREFKNV----------------EYHVDGIMNLREEEAIR 220
M P + +++ Y+ R +F+N+ E HV +
Sbjct: 480 MLP----GVLLVMVQTYIQLRFKFRNISDLQFKDSPEVEELRHEIHVWKRAAASLSAYSK 535
Query: 221 DKQLFRKSVV-TIAFVVLAFFLHDTIGIEPA---------------------VVALTGAS 258
D++L R++++ + + + T IEPA ++ + A
Sbjct: 536 DEELVRQTLMKKVNRLKRSLKKRMTAVIEPAPNYQQTLANLQAKYPIRNKPLLIKCSAAL 595
Query: 259 IL---LLWSRVPPEVALEKVEWATLFFFGGLFIIV------------------------- 290
+ L + PE+ + W L G +F+I+
Sbjct: 596 VFVISLFFLHSVPELQRLSLGWTAL--LGAIFLIILADIEDMEAILARVEWSTLLFFAAL 653
Query: 291 ----GGLVETGLIEDVGKWIVSHISSENE------AILMISWVSAFLSAIIDNIPFTATM 340
L E GLIE +G I E AIL+I WVSA SA +DNIP T M
Sbjct: 654 FILMEALTELGLIEWIGNMTEGIILGVGEDRRLMVAILIILWVSAVASAFVDNIPLTTMM 713
Query: 341 IPLIKSMGG----SINVYPLWWALSLGACLGGNGTAIGASANVVVLGIAYREGIRITFID 396
+ + S+ ++ + PL WAL+LGACLGGNGT IGASANVV G+A + G + TF+
Sbjct: 714 VKITISLAQNSTLNLPLQPLVWALALGACLGGNGTLIGASANVVCAGVAEQHGYKFTFLQ 773
Query: 397 FLKVGMIIMLLTVGAGSLVLIARY 420
F KVG IM+ GS+++ Y
Sbjct: 774 FFKVGFPIMI-----GSIIVTTGY 792
>gb|AAF50958.1| (AE003575) CG15624 gene product [Drosophila melanogaster]
Length = 846
Score = 189 bits (475), Expect = 5e-47
Identities = 139/498 (27%), Positives = 243/498 (47%), Gaps = 90/498 (18%)
Query: 7 IIALGVFISVYAAIISEKIHRTVAAMLGASIMLFLKIVPWENIP------EYLDLDTILL 60
I+A + + YA ++ E RT AM+ SI+ + + + P +++D++ + L
Sbjct: 344 ILAGVILLIFYALLVWELFERTFVAMI-CSILSVTTLACFNDRPNMDEIIQWMDMELLTL 402
Query: 61 LAGMMVIVNISRESGLFEYIAIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLT 120
L MM+++ I E+G+F+Y+A+ IS G ++ + T +VS+ LDN+TTVLLLT
Sbjct: 403 LFCMMLLILILTETGVFDYLAVFCFEISGGKIWPMIYSLCLVTCLVSSVLDNMTTVLLLT 462
Query: 121 PMLLYITRRMGVDPVPYLLAEIFASNIGGTATLIGDPPNIMIASAA-----KLSFNEFIM 175
P+ + + M +DP+P ++ I +NIGG T IGDP +I++++ ++F F+
Sbjct: 463 PVAIRLCEVMQLDPLPVVMGIIVHANIGGALTPIGDPISIIVSTNHFIVDNDVTFPTFVA 522
Query: 176 NMTPIAFLDLFIMVALIYLFY-----------------RREFK----------------- 201
+ P L + + LFY RRE K
Sbjct: 523 HTFPGVILAVIQSCVYLRLFYHNIDALRLNEPKEMSELRREMKVWQRALNAVASCSKDAQ 582
Query: 202 -------------------------NVEYHVDGIMNLREEEAIRDKQLFRKSVVTIAFVV 236
+ E + + + L+++ I++K L +S + FV+
Sbjct: 583 LVRGTLQAKIKQLKRTLRRLQKGVGSTEVYTNTLDELKQKYPIKNKTLLLQSAGALLFVI 642
Query: 237 LAFFLHDTIG---IEPAVVALTGASILLL-WSRVPPEVALEKVEWATLFFFGGLFIIVGG 292
+ FF+ + VAL G +LL+ +R E + ++EW TL FF +F+++
Sbjct: 643 VCFFIQSVPHWRTLPLGWVALLGVILLLIILNRDDMEHLMHRIEWTTLLFFAAMFVMMEC 702
Query: 293 LVETGL---IEDVGKWIVSHISSENE---AILMISWVSAFLSAIIDNIPFTATMIPLIKS 346
+ G+ I ++ + ++ + + AI MI W+SA S+I+D+IP A M+ L+ S
Sbjct: 703 VERLGIFACISELTEHVILSVGKSHRLAMAIFMILWMSALASSILDSIPVAAIMVKLVTS 762
Query: 347 MGGS----INVYPLWWALSLGACLGGNGTAIGASANVVVLGIAYREGIRITFIDFLKVGM 402
+ + + PL WAL+LGA +GGNGT GASANV+ GIA + G +++F +L+
Sbjct: 763 LVAKPSLGLPLQPLVWALTLGASMGGNGTLYGASANVIAAGIAEQHGYKLSFTRYLRTVF 822
Query: 403 IIMLLTVGAGSLVLIARY 420
+ML G + L+ Y
Sbjct: 823 PMML-----GQITLMTVY 835
>gi|11499889 arsenite transport protein (arsB) [Archaeoglobus fulgidus]
>gi|7482910|pir||D69538 arsenite transport protein
(arsB) homolog - Archaeoglobus fulgidus
>gi|2648213|gb|AAB88949.1| (AE000945) arsenite transport
protein (arsB) [Archaeoglobus fulgidus]
Length = 397
Score = 185 bits (464), Expect = 1e-45
Identities = 122/416 (29%), Positives = 217/416 (51%), Gaps = 28/416 (6%)
Query: 7 IIALGVFISVYAAIISE----KIHRTVAAMLGASIMLFLKIVPWENIPEYLDLDTILLLA 62
+I L + I YA I + K+ R A+ +GA++ML ++ + +D +TI+LL
Sbjct: 1 MIELLISILTYALISLQSFYRKMDRPAASTIGAALMLAFGVMSLKEAVRAIDYNTIMLLF 60
Query: 63 GMMVIVNISRESGLFEYIAIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLTPM 122
GMMV+ +G F+++A K+ S G+ R+L ++ +SA N T + +TP+
Sbjct: 61 GMMVLTAYLGIAGFFDWLASKIMGFS-GNGKRLLFTIVFSSGFLSALFVNDTICVFMTPV 119
Query: 123 LLYITRRMGVDPVPYLLAEIFASNIGGTATLIGDPPNIMIASAAKLSFNEFIMNMTPIAF 182
++ + G+ P+P L+A ++N+G T+IG+P N++I + + F +F M P+
Sbjct: 120 VVRVALSAGISPIPLLIALATSANVGSAVTIIGNPQNMLIGLKSGIGFVQFTAKMLPVGV 179
Query: 183 LDLFIMVALIYLFYRREFKNVEYHVDGIMNLREEEAIRDKQLFRKSVVTIAFVVLAFFLH 242
+FI+ ++IY+ YR E G + + E +++L K ++T A V++ F
Sbjct: 180 AGIFIVYSVIYVLYRGEL--------GKLRNGKIEVNLNRRLAAKGLLTFALVLILFV-- 229
Query: 243 DTIGIEPAVVALTGASILLLWSRVPPEVALEKVEWATLFFFGGLFIIVGGLVETGLIEDV 302
T ++ A GA+I+ V P ALEKV+W L F LFI++ G ++
Sbjct: 230 -TEFYPVSLSAFIGAAIMFAIGGVKPREALEKVDWGLLLLFCNLFIVMHGFEKS-----Y 283
Query: 303 GKWIVSHIS-SENEA-ILMISWVSAFLSAIIDNIPFTATMIPLIKSMGGSINVYPLWWAL 360
G+ I+S +S E+ A L S ++ S ++ N+PF ++P K W L
Sbjct: 284 GEKILSMLSFGESFADYLYFSLLTVAGSNLVSNVPFVMMVLPAAKGAAAD-----FWLIL 338
Query: 361 SLGACLGGNGTAIGASANVVVLGIAYREGIRITFIDFLKVGMIIMLLTVGAGSLVL 416
++ + GN T IG+ AN++V A R G+ ++F ++LK G+ + TV G+L++
Sbjct: 339 AMASTFAGNLTLIGSVANLIVAESAERHGVHLSFFEYLKAGVPVTFATVLVGALLI 394
>gi|11230776 pink-eyed dilution protein [Mus musculus] >gi|200285|gb|AAA39908.1|
(M97900) putative open reading frame [Mus musculus]
Length = 833
Score = 176 bits (442), Expect = 4e-43
Identities = 144/509 (28%), Positives = 234/509 (45%), Gaps = 113/509 (22%)
Query: 9 ALGVFISVYAAIISEKIHRTVAAMLGASIMLFLKIVPWE-----NIPEYLDLDTILLLAG 63
A+ + VY II E +HRT+AAMLGA L V + ++ E++D +T+ LL G
Sbjct: 329 AVAILAGVYTLIIFEIVHRTLAAMLGALAALAALAVVGDRPSLTHVVEWIDFETLALLFG 388
Query: 64 MMVIVNISRESG------------------------------------------LFEYIA 81
MM++V + E+G LF +
Sbjct: 389 MMILVAVFSETGFFDYCAVKAYQLSRGRVWAMIFMLCLMAAILSAFLDNVTTMLLFTPVT 448
Query: 82 IKVARISKGDPMRVLL---LFSVTTAVVSAFLDNVTTVLLLTPMLLYITRRMGVDPVPYL 138
I++ + DP +VL+ +F+ +A D +++ L R+MG+D +
Sbjct: 449 IRLCEVLNLDPRQVLIAEVIFTNIGGAATAIGDPPNVIIVSNQEL----RKMGLDFAGFT 504
Query: 139 LAEIFASNIGGTATLIGDPPNIMIASAAKLSFNEFIMNMTPIAFLDL------------- 185
A +F +G L+ P + + L +N+ + N P ++L
Sbjct: 505 -AHMF---LGICLVLLVSFPLLRL-----LYWNKKLYNKEPSEIVELKHEIHVWRLTAQR 555
Query: 186 -----------------------FIMVALIYLFYRREFKNVEYHVDGIMNLREEEAIRDK 222
++ ++ F+R+ + + I L+ + I D+
Sbjct: 556 ISPASREETAVRGLLLEKVLALEHLLAQRLHTFHRQISQEDKNWETNIQELQRKHRISDR 615
Query: 223 QLFRKSVVTIAFVVLAFFLHDT---IGIEPAVVALTGASILLLWSRVPP-EVALEKVEWA 278
L K + + FV+ FFL+ I ++ +A+ GA LL+ + + E+ L +VEWA
Sbjct: 616 SLLVKCLTVLGFVISMFFLNSFVPGIHLDLGWIAILGAIWLLILADIHDFEIILHRVEWA 675
Query: 279 TLFFFGGLFIIVGGLVETGLIEDVGKWIVSHISSENE------AILMISWVSAFLSAIID 332
TL FF LF+++ L L+E VG+ I E AI++I WVSA S++ID
Sbjct: 676 TLLFFAALFVLMEALTHLHLVEYVGEQTALLIKMVPEDQRFAAAIVLIVWVSALASSLID 735
Query: 333 NIPFTATMIPLIKSMGG----SINVYPLWWALSLGACLGGNGTAIGASANVVVLGIAYRE 388
NIPFTATMIP++ ++ S+ PL +AL+LGACLGGNGT IGAS NVV GIA +
Sbjct: 736 NIPFTATMIPVLLNLSQDPEISLPALPLMYALALGACLGGNGTLIGASTNVVCAGIAEKH 795
Query: 389 GIRITFIDFLKVGMIIMLLTVGAGSLVLI 417
G +F++F ++G +ML++ G L+
Sbjct: 796 GYGFSFMEFFRLGFPVMLMSCTIGMCYLL 824
>prf||1905395A pink eyed dilution gene [Homo sapiens]
Length = 838
Score = 173 bits (434), Expect = 4e-42
Identities = 146/513 (28%), Positives = 236/513 (45%), Gaps = 113/513 (22%)
Query: 8 IALGVFISVYAAIISEKIHRTVAAMLGASIMLFLKIVPWE-----NIPEYLDLDTILLLA 62
IA + VYA II E +HRT+AAMLG+ L V + ++ E++D +T+ LL
Sbjct: 333 IATAILAGVYALIIFEIVHRTLAAMLGSLAALAALAVIGDRPSLTHVVEWIDFETLALLF 392
Query: 63 GMMVIVNISRESG------------------------------------------LFEYI 80
GMM++V I E+G LF +
Sbjct: 393 GMMILVAIFSETGFFDYCAVKAYRLSRGRVWAMIIMLCLIAAVLSAFLDNVTTMLLFTPV 452
Query: 81 AIKVARISKGDPMRVLL---LFSVTTAVVSAFLDNVTTVLLLTPMLLYITRRMGVDPVPY 137
I++ + DP +VL+ +F+ +A D +++ L R+MG+D +
Sbjct: 453 TIRLCEVLNLDPRQVLIAEVIFTNIGGAATAIGDPPNVIIVSNQEL----RKMGLDFAGF 508
Query: 138 LLAEIFASNIGGTATLIGDPPNIMIASAAKLSFNEFIMNMTPIAFLDL------------ 185
A +F IG L+ P + + L +N + N P ++L
Sbjct: 509 T-AHMF---IGICIVLLVCFPLLRL-----LYWNRKLYNKEPSEIVELKHEIHVWRLTAQ 559
Query: 186 ------------------------FIMVALIYLFYRREFKNVEYHVDGIMNLREEEAIRD 221
++ ++ F+R+ + + I L+++ I D
Sbjct: 560 RISPASREETAVRRLLLGKVLALEHLLARRLHTFHRQISQEDKNWETNIQELQKKHRISD 619
Query: 222 KQLFRKSVVTIAFVVLAFFLHDT---IGIEPAVVALTGASILLLWSRVPP-EVALEKVEW 277
L K + I FV+ FFL+ I ++ +A+ GA LL+ + + E+ L +VEW
Sbjct: 620 GILLAKCLTVIGFVIFMFFLNSFVPGIHLDLGWIAILGAIWLLILADIHDFEIILHRVEW 679
Query: 278 ATLFFFGGLFIIVGGLVETGLIEDVGKW---IVSHISSENE---AILMISWVSAFLSAII 331
ATL FF LF+++ L LIE VG+ ++ + E AI+++ WVSA S++I
Sbjct: 680 ATLLFFAALFVLMEALAHLHLIEYVGEQTALLIKMVPEEQRLIAAIVLVVWVSALASSLI 739
Query: 332 DNIPFTATMIPLIKSMGGSINVY----PLWWALSLGACLGGNGTAIGASANVVVLGIAYR 387
DNIPFTATMIP++ ++ V PL +AL+ GACLGGNGT IGASANVV GIA +
Sbjct: 740 DNIPFTATMIPVLLNLSHDPEVGLPAPPLMYALAFGACLGGNGTLIGASANVVCAGIAEQ 799
Query: 388 EGIRITFIDFLKVGMIIMLLTVGAGSLVLIARY 420
G +F++F ++G +M+++ G L+ +
Sbjct: 800 HGYGFSFMEFFRLGFPMMVVSCTVGMCYLLVAH 832
>gi|4557811 P protein [Homo sapiens] >gi|548651|sp|Q04671|P_HUMAN P PROTEIN
(MELANOCYTE-SPECIFIC TRANSPORTER PROTEIN)
>gi|345851|pir||S28911 gene DN10 protein - human
>gi|190285|gb|AAA36477.1| (M99564) P protein [Homo
sapiens]
Length = 838
Score = 172 bits (432), Expect = 6e-42
Identities = 145/513 (28%), Positives = 236/513 (45%), Gaps = 113/513 (22%)
Query: 8 IALGVFISVYAAIISEKIHRTVAAMLGASIMLFLKIVPWE-----NIPEYLDLDTILLLA 62
IA + VYA II E +HRT+AAMLG+ L V + ++ E++D +T+ LL
Sbjct: 333 IATAILAGVYALIIFEIVHRTLAAMLGSLAALAALAVIGDRPSLTHVVEWIDFETLALLF 392
Query: 63 GMMVIVNISRESG------------------------------------------LFEYI 80
GMM++V I E+G LF +
Sbjct: 393 GMMILVAIFSETGFFDYCAVKAYRLSRGRVWAMIIMLCLIAAVLSAFLDNVTTMLLFTPV 452
Query: 81 AIKVARISKGDPMRVLL---LFSVTTAVVSAFLDNVTTVLLLTPMLLYITRRMGVDPVPY 137
I++ + DP +VL+ +F+ +A D +++ L R+MG+D +
Sbjct: 453 TIRLCEVLNLDPRQVLIAEVIFTNIGGAATAIGDPPNVIIVSNQEL----RKMGLDFAGF 508
Query: 138 LLAEIFASNIGGTATLIGDPPNIMIASAAKLSFNEFIMNMTPIAFLDL------------ 185
A +F IG L+ P + + L +N + N P ++L
Sbjct: 509 T-AHMF---IGICLVLLVCFPLLRL-----LYWNRKLYNKEPSEIVELKHEIHVWRLTAQ 559
Query: 186 ------------------------FIMVALIYLFYRREFKNVEYHVDGIMNLREEEAIRD 221
++ ++ F+R+ + + I L+++ I D
Sbjct: 560 RISPASREETAVRRLLLGKVLALEHLLARRLHTFHRQISQEDKNWETNIQELQKKHRISD 619
Query: 222 KQLFRKSVVTIAFVVLAFFLHDT---IGIEPAVVALTGASILLLWSRVPP-EVALEKVEW 277
L K + + FV+ FFL+ I ++ +A+ GA LL+ + + E+ L +VEW
Sbjct: 620 GILLAKCLTVLGFVIFMFFLNSFVPGIHLDLGWIAILGAIWLLILADIHDFEIILHRVEW 679
Query: 278 ATLFFFGGLFIIVGGLVETGLIEDVGKW---IVSHISSENE---AILMISWVSAFLSAII 331
ATL FF LF+++ L LIE VG+ ++ + E AI+++ WVSA S++I
Sbjct: 680 ATLLFFAALFVLMEALAHLHLIEYVGEQTALLIKMVPEEQRLIAAIVLVVWVSALASSLI 739
Query: 332 DNIPFTATMIPLIKSMGGSINVY----PLWWALSLGACLGGNGTAIGASANVVVLGIAYR 387
DNIPFTATMIP++ ++ V PL +AL+ GACLGGNGT IGASANVV GIA +
Sbjct: 740 DNIPFTATMIPVLLNLSHDPEVGLPAPPLMYALAFGACLGGNGTLIGASANVVCAGIAEQ 799
Query: 388 EGIRITFIDFLKVGMIIMLLTVGAGSLVLIARY 420
G +F++F ++G +M+++ G L+ +
Sbjct: 800 HGYGFSFMEFFRLGFPMMVVSCTVGMCYLLVAH 832
>gb|AAC13784.1| (U19176) P protein [Homo sapiens]
Length = 838
Score = 172 bits (432), Expect = 6e-42
Identities = 145/513 (28%), Positives = 236/513 (45%), Gaps = 113/513 (22%)
Query: 8 IALGVFISVYAAIISEKIHRTVAAMLGASIMLFLKIVPWE-----NIPEYLDLDTILLLA 62
IA + VYA II E +HRT+AAMLG+ L V + ++ E++D +T+ LL
Sbjct: 333 IATAILAGVYALIIFEIVHRTLAAMLGSLAALAALAVIGDRPSLTHVVEWIDFETLALLF 392
Query: 63 GMMVIVNISRESG------------------------------------------LFEYI 80
GMM++V I E+G LF +
Sbjct: 393 GMMILVAIFSETGFFDYCAVKAYRLSRGRVWAMIIMLCLIAAVLSAFLDNVTTMLLFTPV 452
Query: 81 AIKVARISKGDPMRVLL---LFSVTTAVVSAFLDNVTTVLLLTPMLLYITRRMGVDPVPY 137
I++ + DP +VL+ +F+ +A D +++ L R+MG+D +
Sbjct: 453 TIRLCEVLNLDPRQVLIAEVIFTNIGGAATAIGDPPNVIIVSNQEL----RKMGLDFAGF 508
Query: 138 LLAEIFASNIGGTATLIGDPPNIMIASAAKLSFNEFIMNMTPIAFLDL------------ 185
A +F IG L+ P + + L +N + N P ++L
Sbjct: 509 T-AHMF---IGICLVLLVCFPLLRL-----LYWNRKLYNKEPSEIVELKHEIHVWRLTAQ 559
Query: 186 ------------------------FIMVALIYLFYRREFKNVEYHVDGIMNLREEEAIRD 221
++ ++ F+R+ + + I L+++ I D
Sbjct: 560 RISPASREETAVRRLLLGKVLALEHLLARRLHTFHRQISQEDKNWETNIQELQKKHRISD 619
Query: 222 KQLFRKSVVTIAFVVLAFFLHDT---IGIEPAVVALTGASILLLWSRVPP-EVALEKVEW 277
L K + + FV+ FFL+ I ++ +A+ GA LL+ + + E+ L +VEW
Sbjct: 620 GILLAKCLTVLGFVIFMFFLNSFVPGIHLDLGWIAILGAIWLLILADIHDFEIILHRVEW 679
Query: 278 ATLFFFGGLFIIVGGLVETGLIEDVGKW---IVSHISSENE---AILMISWVSAFLSAII 331
ATL FF LF+++ L LIE VG+ ++ + E AI+++ WVSA S++I
Sbjct: 680 ATLLFFAALFVLMEALAHLHLIEYVGEQTALLIKMVPEEQRLIAAIVLVVWVSALASSLI 739
Query: 332 DNIPFTATMIPLIKSMGGSINVY----PLWWALSLGACLGGNGTAIGASANVVVLGIAYR 387
DNIPFTATMIP++ ++ V PL +AL+ GACLGGNGT IGASANVV GIA +
Sbjct: 740 DNIPFTATMIPVLLNLSHDPEVGLPAPPLMYALAFGACLGGNGTLIGASANVVCAGIAEQ 799
Query: 388 EGIRITFIDFLKVGMIIMLLTVGAGSLVLIARY 420
G +F++F ++G +M+++ G L+ +
Sbjct: 800 HGYGFSFMEFFRLGFPMMVVSCTVGMCYLLVAH 832
>pir||A57173 oculocutaneous albinism II-related protein P - human (fragment)
Length = 532
Score = 171 bits (428), Expect = 2e-41
Identities = 145/510 (28%), Positives = 234/510 (45%), Gaps = 113/510 (22%)
Query: 8 IALGVFISVYAAIISEKIHRTVAAMLGASIMLFLKIVPWE-----NIPEYLDLDTILLLA 62
IA + VYA II E +HRT+AAMLG+ L V + ++ E++D +T+ LL
Sbjct: 27 IATAILAGVYALIIFEIVHRTLAAMLGSLAALAALAVIGDRPSLTHVVEWIDFETLALLF 86
Query: 63 GMMVIVNISRESG------------------------------------------LFEYI 80
GMM++V I E+G LF +
Sbjct: 87 GMMILVAIFSETGFFDYCAVKAYRLSRGRVWAMIIMLCLIAAVLSAFLDNVTTMLLFTPV 146
Query: 81 AIKVARISKGDPMRVLL---LFSVTTAVVSAFLDNVTTVLLLTPMLLYITRRMGVDPVPY 137
I++ + DP +VL+ +F+ +A D +++ L R+MG+D +
Sbjct: 147 TIRLCEVLNLDPRQVLIAEVIFTNIGGAATAIGDPPNVIIVSNQEL----RKMGLDFAGF 202
Query: 138 LLAEIFASNIGGTATLIGDPPNIMIASAAKLSFNEFIMNMTPIAFLDL------------ 185
A +F IG L+ P + + L +N + N P ++L
Sbjct: 203 T-AHMF---IGICLVLLVCFPLLRL-----LYWNRKLYNKEPSEIVELKHEIHVWRLTAQ 253
Query: 186 ------------------------FIMVALIYLFYRREFKNVEYHVDGIMNLREEEAIRD 221
++ ++ F+R+ + + I L+++ I D
Sbjct: 254 RISPASREETAVRRLLLGKVLALEHLLARRLHTFHRQISQEDKNWETNIQELQKKHRISD 313
Query: 222 KQLFRKSVVTIAFVVLAFFLHDT---IGIEPAVVALTGASILLLWSRVPP-EVALEKVEW 277
L K + + FV+ FFL+ I ++ +A+ GA LL+ + + E+ L +VEW
Sbjct: 314 GILLAKCLTVLGFVIFMFFLNSFVPGIHLDLGWIAILGAIWLLILADIHDFEIILHRVEW 373
Query: 278 ATLFFFGGLFIIVGGLVETGLIEDVGKW---IVSHISSENE---AILMISWVSAFLSAII 331
ATL FF L +++ L LIE VG+ ++ + E AI+++ WVSA S++I
Sbjct: 374 ATLLFFAALEVLMEALAHLHLIEYVGEQTALLIKMVPEEQRLIAAIVLVVWVSALASSLI 433
Query: 332 DNIPFTATMIPLIKSMGGSINVY----PLWWALSLGACLGGNGTAIGASANVVVLGIAYR 387
DNIPFTATMIP++ ++ V PL +AL+LGACLGGNGT IGAS NVV GIA +
Sbjct: 434 DNIPFTATMIPVLLNLSHDPEVGLPAPPLMYALALGACLGGNGTLIGASTNVVCAGIAEK 493
Query: 388 EGIRITFIDFLKVGMIIMLLTVGAGSLVLI 417
G +F++F ++G +ML++ G L+
Sbjct: 494 HGYGFSFMEFFRLGFPVMLMSCTIGMCYLL 523
>gb|AAF47636.1| (AE003474) CG13801 gene product [Drosophila melanogaster]
Length = 690
Score = 159 bits (398), Expect = 6e-38
Identities = 131/471 (27%), Positives = 203/471 (42%), Gaps = 65/471 (13%)
Query: 12 VFISVYAAIISEKIHRTVAAMLGASIMLFLKIV-----PWENIPEYLDLDTILLLAGMMV 66
+ I +YA II E R ++ +L ++ L L V E I ++D +T++LL G M+
Sbjct: 211 LLIGLYAIIIWEFSDRILSTLLITAMSLALLTVLGSRPTLETIVSWVDWETMMLLLGNMI 270
Query: 67 IVNISRESGLFEYIAIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLTPMLLYI 126
I + ++G F+Y+A+ RISKG ++ L + S +DN T VLL P ++ +
Sbjct: 271 ITSRMADTGFFDYLAVVAYRISKGHAWLLIGLLGFFVGLTSTVVDNATVVLLFCPPVIRL 330
Query: 127 TRRMGVDPVPYLLAEIFASNIGGTATLIGDPPNIMIAS-----AAKLSFNEFIMNMTPIA 181
M + L+ +NIGG+ T + PPN +IA+ +A ++F F + M P A
Sbjct: 331 CEVMDLRTTLVLIIVAIYANIGGSITPVSGPPNTIIATNKMVESAGINFVRFSLLMLPTA 390
Query: 182 FLDLFIMVALIYLFY-----------------RREFKNVEYHVD---------------- 208
+ L LIY RRE + +
Sbjct: 391 LICLASTFGLIYWTMGKKIYILDEDQVNLAEKRRENTRTSFDIQLRVAELRRQPRSKVIP 450
Query: 209 -------GIMNLREEEAIRDKQLFRKSVVTIAFVVLAFFLHDTIGIEPA-----VVALTG 256
+ L +R K L +S++ ++F F L P + L+
Sbjct: 451 PAESYFITLATLEASNFVRKKVLLVESLLALSFAAFCFILQSVPWAIPGASLGWISILSA 510
Query: 257 ASILLLWSRVPPEVALEKVEWATLFFFGGLFIIVGGLVETGLIEDVGKWIVSHISSENEA 316
+L+L + + VEW + LFI + E GLI +G +VS I +E+
Sbjct: 511 FLLLILIDQKDIIKVMASVEWGIMLLLASLFIFTMVVDELGLIHWLGSQVVSVILRVDES 570
Query: 317 ------ILMISWVSAFLSAIIDNIPFTATMIPLIKSM----GGSINVYPLWWALSLGACL 366
+L+I W+SA LSA I N M+ L M + + PL WA S+G
Sbjct: 571 YQTMVGMLLILWLSALLSAFIHNAAVAPIMVKLCTDMVVYDQVQMPLLPLIWATSMGTSY 630
Query: 367 GGNGTAIGASANVVVLGIAYREGIRITFIDFLKVGMIIMLLTVGAGSLVLI 417
G NGT +G+ AN + G +ITF F VG +IML TV S+ LI
Sbjct: 631 GANGTLLGSLANEFAAVVGKAHGYKITFRSFFVVGFLIMLFTVVICSIFLI 681
>pir||B72758 hypothetical protein APE0055 - Aeropyrum pernix (strain K1)
>gi|5103443|dbj|BAA78964.1| (AP000058) 430aa long
hypothetical protein [Aeropyrum pernix]
Length = 430
Score = 150 bits (376), Expect = 2e-35
Identities = 106/416 (25%), Positives = 191/416 (45%), Gaps = 23/416 (5%)
Query: 5 LEIIALGVFISVYAAIISEKIHRTVAAMLGASIMLFLKIVPWENIPEYLDLDTILLLAGM 64
++++A +F ++S + AA+ G + ++ L E +++ + I +L GM
Sbjct: 1 MDLVAALLFTLTIMLVVSRYVDEVAAALAGVTALILLTNYTPEEAFNFVEWNVIAILLGM 60
Query: 65 MVIVNISRESGLFEYIAIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLTPMLL 124
+I E G E I++ S G + LL ++ + +S F+DNV +LL+ + +
Sbjct: 61 WIIAGYMIEGGFTE-ATIRLVSRSAGTYRKFLLYMALLSGFISMFIDNVLVILLVGSLTI 119
Query: 125 YITRRMGVDPVPYLLAEIFASNIGGTATLIGDPPNIMIASAAKLSFNEFIM-----NMTP 179
++ G +PV +L F++N GTA L+GD P ++ + A F +FI + P
Sbjct: 120 AAAKKAGGNPVLAILLVGFSANFMGTALLMGDLPPQLLHTIAGAEFLDFIWTRGKPSSFP 179
Query: 180 IAFLDLFIMVALIYLFYRREFKNVEYHVDGIMNLREEEAIRDKQLFRKSVVTIAFVVLAF 239
+ + + + Y+ + R N G+ E+ L S+ V+A
Sbjct: 180 LLTATFLLTLGVFYILFIRREPNSRIDDAGLSG----ESTNRGGLLIISLTFFTMTVIAM 235
Query: 240 FLHDTIGIEPAVVALTGASILLLW----------SRVPPEVALEKVEWATLFFFGGLFII 289
L +G + + GAS L L V E AL+ VEW L F+ LF +
Sbjct: 236 ALRPLLGFPLGFITMAGASQLALTVEVLRRLGLAGMVEFENALKHVEWRALLFYAALFSL 295
Query: 290 VGGLVETGLIEDVGKWIVSHISSENE-AILMISWVSAFLSAIIDNIPFTATMIPLIKSMG 348
VGGL G+IE++ + +V +SS+ A ++ W LS +I++ T + ++K
Sbjct: 296 VGGLESEGVIEEIARLLVGSVSSDPAIAYTVMYWSVGLLSLVIEHDALLLTFLYIVKDAA 355
Query: 349 GSINVYP--LWWALSLGACLGGNGTAIGASANVVVLGIAYREGIRITFIDFLKVGM 402
+ P ++W ++ A L N T A A V + ++ REG R+ ++FLK +
Sbjct: 356 SLAGIDPWNIYWGMAWSATLASNATTAAAPALYVAVAMSDREGHRVRALEFLKYSL 411
>gb|AAK40494.1| Arsenite transport protein (arsB) [Sulfolobus solfataricus]
Length = 411
Score = 150 bits (376), Expect = 2e-35
Identities = 110/409 (26%), Positives = 206/409 (49%), Gaps = 23/409 (5%)
Query: 7 IIALGVFISVYAAIISEKIHRT---VAAMLGASIMLFLKIVPWENIPEYLDLDTILLLAG 63
I AL V + Y IIS I + + G +M+ L I+ E + ++LD IL L
Sbjct: 3 ISALIVMVITYCLIISRSITKIPPWASMFFGGILMVILGIISPEEALQSINLDVILFLIT 62
Query: 64 MMVIVNISRESGLFEYIAIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLTPML 123
+ + SG +++A K+ K +P +VL + + ++S + N TP++
Sbjct: 63 LFTFASALEVSGFLKFLAYKIIEKFK-EPRKVLFYILLYSGLLSNLVTNDGVSASWTPVI 121
Query: 124 LYITRRMGVDPVPYLLAEIFASNIGGTATLIGDPPNIMIA--SAAKLSFNEFIMNMTPIA 181
L ++R +GV VP+L A IG G+P N++IA S K F F + +T +
Sbjct: 122 LELSRMIGVSEVPFLYALAVGVTIGSVIMPTGNPQNLLIALESGIKNPFITFTIYLTLPS 181
Query: 182 FLDLFIMVALIYLFYRREFKNVEYHVDGIMNLREEEAIR---DKQLFRKSVVTIAFVVLA 238
+ L I +++ +R+ + +N+++EE + D++L ++ + ++
Sbjct: 182 IISLIIAYFILFRLFRKSLS-----LPSGINIKKEEEEKVDFDRRLGYLTLTLLVVTIIL 236
Query: 239 FFLHDTIGIEPAVVALTGASILLLWSRVPPEVALEKVEWATLFFFGGLFIIVGGLVETGL 298
FF I+ + +L +SILLL + ++ + +++W T+ FF GLFI G++++G+
Sbjct: 237 FFSLSFFKIDILLGSLVTSSILLLLTEKRRDI-VRRMDWPTILFFIGLFIFTDGVLKSGI 295
Query: 299 IEDVGKWIVSHISSENEAILMISWVSAFLSAIIDNIPFTATMIPLIKSMGGSINVYPLWW 358
I+ +S+ +++ I VS LS ++ N+P A IP++ S G V W
Sbjct: 296 IQ-----YLSNFLPPPDSVASIMIVSILLSQVLSNVPLVAIYIPIMISHSGITVVD--WL 348
Query: 359 ALSLGACLGGNGTAIGASANVVVLGIA-YREGIRITFIDFLKVGMIIML 406
AL+ G+ + GN T +GA++NV++ + R G F++F+K + I++
Sbjct: 349 ALAAGSTIAGNFTILGAASNVIISEASESRGGKGFNFVEFMKYTIPILI 397
>gb|AAC13783.1| (U19176) P protein, truncated [Homo sapiens]
Length = 668
Score = 141 bits (351), Expect = 2e-32
Identities = 83/208 (39%), Positives = 123/208 (58%), Gaps = 11/208 (5%)
Query: 8 IALGVFISVYAAIISEKIHRTVAAMLGASIMLFLKIVPWE-----NIPEYLDLDTILLLA 62
IA + VYA II E +HRT+AAMLG+ L V + ++ E++D +T+ LL
Sbjct: 333 IATAILAGVYALIIFEIVHRTLAAMLGSLAALAALAVIGDRPSLTHVVEWIDFETLALLF 392
Query: 63 GMMVIVNISRESGLFEYIAIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLTPM 122
GMM++V I E+G F+Y A+K R+S+G ++++ + AV+SAFLDNVTT+LL TP+
Sbjct: 393 GMMILVAIFSETGFFDYCAVKAYRLSRGRVWAMIIMLCLIAAVLSAFLDNVTTMLLFTPV 452
Query: 123 LLYITRRMGVDPVPYLLAEIFASNIGGTATLIGDPPNIMIASAAK-----LSFNEFIMNM 177
+ + + +DP L+AE+ +NIGG AT IGDPPN++I S + L F F +M
Sbjct: 453 TIRLCEVLNLDPRQVLIAEVIFTNIGGAATAIGDPPNVIIVSNQELRKMGLDFAGFTAHM 512
Query: 178 TPIAFLDLFIMVALIYLFY-RREFKNVE 204
L L + L+ L Y R+ N E
Sbjct: 513 FIGICLVLLVCFPLLRLLYWNRKLYNKE 540
>gi|11433867 oculocutaneous albinism II (pink-eye dilution (murine) homolog)
[Homo sapiens]
Length = 532
Score = 141 bits (351), Expect = 2e-32
Identities = 83/208 (39%), Positives = 123/208 (58%), Gaps = 11/208 (5%)
Query: 8 IALGVFISVYAAIISEKIHRTVAAMLGASIMLFLKIVPWE-----NIPEYLDLDTILLLA 62
IA + VYA II E +HRT+AAMLG+ L V + ++ E++D +T+ LL
Sbjct: 250 IATAILAGVYALIIFEIVHRTLAAMLGSLAALAALAVIGDRPSLTHVVEWIDFETLALLF 309
Query: 63 GMMVIVNISRESGLFEYIAIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLTPM 122
GMM++V I E+G F+Y A+K R+S+G ++++ + AV+SAFLDNVTT+LL TP+
Sbjct: 310 GMMILVAIFSETGFFDYCAVKAYRLSRGRVWAMIIMLCLIAAVLSAFLDNVTTMLLFTPV 369
Query: 123 LLYITRRMGVDPVPYLLAEIFASNIGGTATLIGDPPNIMIASAAK-----LSFNEFIMNM 177
+ + + +DP L+AE+ +NIGG AT IGDPPN++I S + L F F +M
Sbjct: 370 TIRLCEVLNLDPRQVLIAEVIFTNIGGAATAIGDPPNVIIVSNQELRKMGLDFAGFTAHM 429
Query: 178 TPIAFLDLFIMVALIYLFY-RREFKNVE 204
L L + L+ L Y R+ N E
Sbjct: 430 FIGICLVLLVCFPLLRLLYWNRKLYNKE 457
>sp|Q01255|ARSB_STAXY ARSENICAL PUMP MEMBRANE PROTEIN >gi|282259|pir||B41902 arsenical
pump membrane protein - Staphylococcus xylosus
>gi|155345|gb|AAA27588.1| (M80565) arsenic efflux pump
protein [Plasmid pSX267]
Length = 429
Score = 131 bits (325), Expect = 2e-29
Identities = 96/416 (23%), Positives = 217/416 (52%), Gaps = 18/416 (4%)
Query: 5 LEIIALGVFISVYAAIISEK--IHRTVAAMLGASIMLFLKIVPWENIPEYLDL--DTILL 60
+ I+A+ +F+ +I + + + A++GA + + +V + ++ E + + L
Sbjct: 1 MTILAIVIFLLTLIFVIWQPKGLDIGITALIGAVVAIITGVVSFSDVLEVTGIVWNATLT 60
Query: 61 LAGMMVIVNISRESGLFEYIAIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLT 120
+++I I E G FE+ AI + + S G+ +++ + + A+V+AF N L+LT
Sbjct: 61 FVAVILISLILDEIGFFEWSAIHMVKASNGNGLKMFVFIMLLGAIVAAFFANDGAALILT 120
Query: 121 PMLLYITRRMGVDP---VPYLLAEIFASNIGGTATLIGDPPNIMIASAAKLSFNEFIMNM 177
P++L + R +G + P+++A F ++ ++ + NI+ A + F E+ M
Sbjct: 121 PIVLAMVRNLGFNKKVIFPFIIASGFIADTTSLPLIVSNLVNIVSADYFDIGFIEYFSRM 180
Query: 178 TPIAFLDLFIMVALIYLFYRREFKNVEYHVDGIMNLREEEAIRDKQLFRKSVVTIAFVVL 237
L + +++L++R+ ++ + + + + I+D +LF+ S + +A +++
Sbjct: 181 IIPNIFSLIASILVLWLYFRKSIPKT-FNTENLSD--PKNVIKDPKLFKLSWIVLAILLV 237
Query: 238 AFFLHDTIGIEPAVVALTGASILLLWSRVPPEVALEKV----EWATLFFFGGLFIIVGGL 293
+ + + I I +++A A I ++ +R V ++V W + F G++++V GL
Sbjct: 238 GYLVSEFIQIPVSIIAGIIALIFVILARKSKAVHTKQVIKGAPWNIVVFSIGMYLVVFGL 297
Query: 294 VETGLIEDVGKWIVSHISSEN--EAILMISWVSAFLSAIIDNIP-FTATMIPLIKSMGGS 350
G+ +G I+++ISS +I+ + +++AFLS+I++N+P I + +S
Sbjct: 298 KNVGITTILGD-ILTNISSYGLFSSIMGMGFIAAFLSSIMNNMPTVLIDAIAIGQSSATG 356
Query: 351 INVYPLWWALSLGACLGGNGTAIGASANVVVLGIAYREGIRITFIDFLKVGMIIML 406
I + +A +G+ LG T IG+ A ++ L + ++G++I++ + K G+II +
Sbjct: 357 ILKEGMVYANVIGSDLGPKITPIGSLATLLWLHVLTQKGVKISWGTYFKTGIIITI 412
>sp|P30329|ARSB_STAAU ARSENICAL PUMP MEMBRANE PROTEIN >gi|282238|pir||C41903 arsenical
pump membrane protein - Staphylococcus aureus
>gi|150728|gb|AAA25637.1| (M86824) arsenic efflux pump
protein [Plasmid pI258]
Length = 429
Score = 129 bits (321), Expect = 6e-29
Identities = 95/416 (22%), Positives = 216/416 (51%), Gaps = 18/416 (4%)
Query: 5 LEIIALGVFISVYAAIISEK--IHRTVAAMLGASIMLFLKIVPWENIPEYLDL--DTILL 60
+ I+A+ +F+ +I + + + A++GA + + +V ++ E + + L
Sbjct: 1 MTILAIVIFLLTLTFVIWQPKGLDIGITALIGAVVAIITGVVSLSDVLEVTGIVWNATLT 60
Query: 61 LAGMMVIVNISRESGLFEYIAIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLT 120
+++I I E G FE+ AI + + S G+ +++ + + A+V+AF N L+LT
Sbjct: 61 FVAVILISLILDEIGFFEWSAIHMVKASNGNGLKMFVFIMLLGAIVAAFFANDGAALILT 120
Query: 121 PMLLYITRRMGVDP---VPYLLAEIFASNIGGTATLIGDPPNIMIASAAKLSFNEFIMNM 177
P++L + R +G + P+++A F ++ ++ + NI+ A + F E+ M
Sbjct: 121 PIVLAMVRNLGFNQKVIFPFIIASGFIADTTSLPLIVSNLVNIVSADYFDIGFIEYFSRM 180
Query: 178 TPIAFLDLFIMVALIYLFYRREFKNVEYHVDGIMNLREEEAIRDKQLFRKSVVTIAFVVL 237
L + +++L++R+ + + + + + AI+D +LF+ S + +A +++
Sbjct: 181 IIPNIFSLIASILVLWLYFRKSIPKT-FDTENLSD--PKSAIKDSKLFKLSWIVLAVLLV 237
Query: 238 AFFLHDTIGIEPAVVALTGASILLLWSRVPPEVALEKV----EWATLFFFGGLFIIVGGL 293
+ + + I I +++A A I ++ +R V ++V W + F G++++V GL
Sbjct: 238 GYLVSEFIQIPVSIIAGIIAFIFVILARKSKAVHTKQVIKGAPWNIVVFSIGMYLVVFGL 297
Query: 294 VETGLIEDVGKWIVSHISSEN--EAILMISWVSAFLSAIIDNIP-FTATMIPLIKSMGGS 350
G+ +G ++++IS+ +I+ + +++AFLS+I++N+P I + +S
Sbjct: 298 KNVGITTILGD-VLTNISNYGLFSSIMGMGFIAAFLSSIMNNMPTVLIDAIAIGQSSATG 356
Query: 351 INVYPLWWALSLGACLGGNGTAIGASANVVVLGIAYREGIRITFIDFLKVGMIIML 406
I + +A +G+ LG T IG+ A ++ L + ++G++I++ + K G+II +
Sbjct: 357 ILKEGMVYANVIGSDLGPKITPIGSLATLLWLHVLTQKGVKISWGTYFKTGIIITI 412
>emb|CAC11316.1| (AL445063) probable arsenical pump membrane protein [Thermoplasma
acidophilum]
Length = 435
Score = 126 bits (313), Expect = 5e-28
Identities = 97/359 (27%), Positives = 184/359 (51%), Gaps = 17/359 (4%)
Query: 74 SGLFEYIAIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLTPMLLYITRRMGVD 133
SG FEY AI++++++ G+ +++ + + + +SAF N T L+LTP++ IT R G+D
Sbjct: 82 SGFFEYYAIRISKMAGGNGLKLFVFIVLLGSAISAFFANDGTALVLTPIVSAITARTGMD 141
Query: 134 ---PVPYLLAEIFASNIGGTATLIGDPPNIMIASAAKLSFNEFIMNMTPIAFLDLFIMVA 190
+ +++A F ++ +I + NI+ A +SF ++ M + + +
Sbjct: 142 KRRALAFVMATGFIADSSSLPFIISNLVNIIGAGYFGVSFAQYAETMIVPDIVSIMASLG 201
Query: 191 LIYLFYRREFKNVEYHVDGIMNLREEEAIRDKQLFRKSVVTIAFVVLAFFLHDTIGIEPA 250
++ L YR+E +VEY + + + E I D ++FR ++ IA VVLA+FL I +
Sbjct: 202 VLILIYRKE-ASVEYSTEDVGD--ENRVIVDSRIFRLALPFIAIVVLAYFLSSLDSIPVS 258
Query: 251 VVALTGASILLLWSRVPPEV----ALEKVEWATLFFFGGLFIIVGGLVETGLIEDVGKWI 306
+AL A +L +RV ++ L + W + F G++++V G GL + + +
Sbjct: 259 FIALPAALTVLYIARVNGKINTGLVLREAPWQIVLFSLGMYVVVYGFGNAGLTDLITDLM 318
Query: 307 VSHISSENEAILMISWV-SAFLSAIIDNIPFTATMIPLIKSMGGSINVYPLWWALSLGAC 365
S +S N A ++ + FL+ ++N+P T + + S+ G+ L +A +G
Sbjct: 319 RSLMSLGNPAYTLLGGLFFGFLAGAMNNLPSTMMGVLTVSSLSGN---RFLLYANVIGND 375
Query: 366 LGGNGTAIGASANVV-VLGIAYREGIRITFIDFLKVGMIIML--LTVGAGSLVLIARYG 421
+G T IG+ A ++ + + + GI +T + ++K+G I L L V SL + G
Sbjct: 376 IGPKFTPIGSLATLLWMYTLRRKHGIEVTPLYYMKIGFIAALPVLVVTLLSLYAVVSLG 434
>pir||G69779 arsenical pump membrane protein homolog ydfA - Bacillus subtilis
>gi|1881341|dbj|BAA19368.1| (AB001488) SIMILAR TO
ARSENICAL PUMP MEMBRANE PROTEIN. [Bacillus subtilis]
>gi|2632834|emb|CAB12341.1| (Z99106) similar to
arsenical pump membrane protein [Bacillus subtilis]
Length = 435
Score = 123 bits (307), Expect = 3e-27
Identities = 101/419 (24%), Positives = 211/419 (50%), Gaps = 22/419 (5%)
Query: 7 IIALGVFISVYAAIISEKIHRTV--AAMLGASIMLFLKIVPWENIPEYLDL--DTILLLA 62
I+A+ +F+ +I + + ++ +A GA + L +V + ++ + + L
Sbjct: 5 ILAVFIFLLTLVLVIWQPKNLSIGWSACGGAVLALIAGVVNFHDVLTVTGIVWNATLAFV 64
Query: 63 GMMVIVNISRESGLFEYIAIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLTPM 122
+++I I G FE+ A+ +A+ +KG +R+ + S+ A+V+A N L+LTP+
Sbjct: 65 AIILISLILDNIGFFEWAALHMAKAAKGYGVRMFVYVSLLGAIVAALFANDGAALILTPI 124
Query: 123 LLYITRRMGVDP---VPYLLAEIFASNIGGTATLIGDPPNIMIASAAKLSFNEFIMNMTP 179
+L + R + + P+++A F ++ ++ + NI+ A ++F ++ M
Sbjct: 125 VLAMVRALHFNEKLVFPFIIASGFIADTTSLPFVVSNLVNIVSADYFHITFIDYASRMVV 184
Query: 180 IAFLDLFIMVALIYLFYRREFKNVEYHVDGIMNLREEEAIRDKQLFRKSVVTIAFVVLAF 239
L + ++YLF+R K++ D + EAI+D+ +FR S + +++ +
Sbjct: 185 PYLFSLLASIIVLYLFFR---KSIPKRYDLTEVKKPVEAIKDQNMFRLSWYILGLLLIGY 241
Query: 240 FLHDTIGIEPAVVALTGASILLLWSRVPPEVALEKV----EWATLFFFGGLFIIVGGLVE 295
F + I +VVA + A I L+ ++ P V +KV WA +FF G++++V G+
Sbjct: 242 FASEFFSIPVSVVAGSIAIIFLIAAQKSPAVHTKKVVKEAPWAIVFFSIGMYVVVYGVRN 301
Query: 296 TGLIEDVGKWIVSHISSEN--EAILMISWVSAFLSAIIDNIPFTATMIPLIKSMGGSINV 353
GL DV ++ + + + + +++A LS+I++N+P MI + G +
Sbjct: 302 AGL-TDVLSDVIQAAADQGLFAGTIGMGFIAAILSSIMNNLP--TVMIDALAIAGTDTHG 358
Query: 354 Y---PLWWALSLGACLGGNGTAIGASANVVVLGIAYREGIRITFIDFLKVGMIIMLLTV 409
L +A +G+ LG T IG+ A ++ L + +G++I++ + K G+I+ + T+
Sbjct: 359 MMREALIYANVIGSDLGPKITPIGSLATLLWLHVLSHKGMKISWGTYFKTGIILTIPTL 417
>gb|AAF69238.1|AF173880_1 (AF173880) arsenical membrane pump [Acidithiobacillus ferrooxidans]
Length = 436
Score = 123 bits (305), Expect = 5e-27
Identities = 106/423 (25%), Positives = 198/423 (46%), Gaps = 31/423 (7%)
Query: 7 IIALGVFISVYAAIISEKIHRTV--AAMLGASIMLFLKIVPWENIPE--YLDLDTILLLA 62
++A+ +F+ +I + ++ +AM GA + L ++ W +IP ++ D
Sbjct: 1 MLAVAIFLVTLILVIWQPKGLSIGWSAMGGAVVALATGVITWSDIPIVWHIVWDATFTFV 60
Query: 63 GMMVIVNISRESGLFEYIAIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLTPM 122
+++I I E+G F + A+ V R G + L V A+++A N LLLTP+
Sbjct: 61 ALIIISLILDEAGFFHWAALHVVRWGGGRGRLLFPLIVVLGAMIAAVFANDGAALLLTPI 120
Query: 123 LLYITRRMGVDPV---PYLLAEIFASNIGGTATLIGDPPNIMIASAAKLSFNEFIMNMTP 179
++ I R+ P +++A F ++ +I + NI+ A+ +SF+ + M P
Sbjct: 121 VMAILLRLDFTPAATFAFVIATGFVADTTSLPLMISNLVNIVSANYFNISFDRYATVMVP 180
Query: 180 IAFLDLFIMVALIYLFYRREFKNVEYHVDGIMNLREEEAIRDKQLFRKSVVTIAFVVLAF 239
+ + L + +++L++RR Y + I D +FR S + +++A+
Sbjct: 181 VDLVALAATLGVLWLYFRRVVPR-RYLTRDLP--EPASVIMDHVVFRASFPVLILLLVAY 237
Query: 240 FLHDTIGIEPAVVALTGASILLL----W------SRVPPEVALEKVEWATLFFFGGLFII 289
F+ + +VV TGA ILL W +R+P L + WA + F G++++
Sbjct: 238 FVTAQWQVPVSVVTGTGALILLALAGRWLQGGRGARIPVRKVLREAPWAIVVFSLGMYLV 297
Query: 290 VGGLVETGLIEDVG---KWIVSHISSENEAILMISWVSAFLSAIIDNIPFTATMIPLIKS 346
V GL GL V W H A L +++A LS+I++N+P I
Sbjct: 298 VYGLRNAGLTSYVAMALHWFAGH--GTVAAALGTGFLAALLSSIMNNMPAVLVGALAIHQ 355
Query: 347 MGGSINVYPLW-----WALSLGACLGGNGTAIGASANVVVLGIAYREGIRITFIDFLKVG 401
+ S+ PL +A +G LG T IG+ A ++ L + R+G+ +T+ +++ G
Sbjct: 356 L-SSVATDPLLREIMVYANVIGCDLGPKFTPIGSLATLLWLHVLSRKGMTVTWGQYMRTG 414
Query: 402 MII 404
++I
Sbjct: 415 LLI 417
>dbj|BAB06718.1| (AP001517) arsenic efflux pump [Bacillus halodurans]
Length = 436
Score = 122 bits (302), Expect = 1e-26
Identities = 99/422 (23%), Positives = 210/422 (49%), Gaps = 24/422 (5%)
Query: 7 IIALGVFISVYAAIISEKIHRTV--AAMLGASIMLFLKIVPWENIPEYLDL--DTILLLA 62
I+A +F+ +I + ++ +A +GA + L +V + ++ + + L
Sbjct: 5 IVASLIFLFTLVLVIWQPRGLSIGWSATIGAVLALLAGVVDFADVQAVTGIVWNATLTFV 64
Query: 63 GMMVIVNISRESGLFEYIAIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLTPM 122
+++I I E G FE+ A+ +AR++ G +++ L ++ A+V+A N L+LTP+
Sbjct: 65 AIIIISLILDEIGFFEWSALHMARVANGSGIKMFLYITLLGAIVAALFANDGAALILTPI 124
Query: 123 LLYITRRMGVDP---VPYLLAEIFASNIGGTATLIGDPPNIMIASAAKLSFNEFIMNMTP 179
+L + R + +P+++A F ++ ++ + NI+ A + F E+ M
Sbjct: 125 VLAMVRALKFKEAMVLPFVMASGFIADTTSLPLIVSNLVNIVSADFFNIGFVEYATRMVV 184
Query: 180 IAFLDLFIMVALIYLFYRREFKNVEYHVDGIMNLREEEAIRDKQLFRKSVVTIAFVVLAF 239
L + ++YL++R++ Y + + + EAI+DK +F+ S V +A +++ +
Sbjct: 185 PNLFALAASIVVLYLYFRKDMPKT-YDLSQLK--KPHEAIKDKAMFKLSWVILAVLLIGY 241
Query: 240 FLHDTIGIEPAVVALTGASILLLWSR--------VPPEVALEKVEWATLFFFGGLFIIVG 291
F+ + + I + VA+ A + L R + ++ WA + F G++++V
Sbjct: 242 FVSEFVHIPVSFVAMPIAFVFYLIFRRASGKNKALNTTGIIKGAPWAIVVFSIGMYVVVY 301
Query: 292 GLVETGLIEDVGKWI-VSHISSENEAILMISWVSAFLSAIIDNIP---FTATMIPLIKSM 347
GL GL + I ++ + + +++A LS++++N+P A I +M
Sbjct: 302 GLRNVGLTNILADIIELAAAQGLFAGTMAMGFIAAILSSLMNNMPTVMINALAIADTNTM 361
Query: 348 GGSINVYPLWWALSLGACLGGNGTAIGASANVVVLGIAYREGIRITFIDFLKVGMIIMLL 407
G I L +A +G+ LG T IG+ A ++ L + ++G++IT+ + KVG+I+ +
Sbjct: 362 G--IMREALIYANVIGSDLGPKITPIGSLATLLWLHVLSKKGMKITWGYYFKVGIILTVP 419
Query: 408 TV 409
T+
Sbjct: 420 TL 421
>emb|CAB88405.1| (AJ288983) ArsB transmembrane efflux channel [Serratia marcescens]
Length = 429
Score = 118 bits (292), Expect = 2e-25
Identities = 97/406 (23%), Positives = 203/406 (49%), Gaps = 26/406 (6%)
Query: 30 AAMLGASIMLFLKIVPWENIPEYLDL--DTILLLAGMMVIVNISRESGLFEYIAIKVARI 87
+A LGA + L +V +IP + + +++I + ESG FE+ A+ VAR
Sbjct: 27 SASLGAILALLTGVVHLGDIPVVWQIVWNATATFIAVIIISLLLDESGFFEWAALHVARW 86
Query: 88 SKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLTPMLLYITRRMGVD---PVPYLLAEIFA 144
G + + A+V+A N L+LTP+++ + +G + +++A F
Sbjct: 87 GNGRGRLLFTWIVLLGAIVAALFANDGAALILTPIVIAMLLALGFSRGATLAFIMAAGFI 146
Query: 145 SNIGGTATLIGDPPNIMIASAAKLSFNEFIMNMTPIAFLDLFIMVALIYLFYRREFKNVE 204
++ ++ + NI+ A KL F+E+ M P+ + + +++LF+R++ V
Sbjct: 147 ADTASLPLIVSNLVNIVSADFFKLGFSEYAAVMVPVNLAAIAATLVMLHLFFRKDIPAV- 205
Query: 205 YHVDGIMNLREEEAIRDKQLFRKSVVTIAFVVLAFFLHDTIGIEPAVVALTGASILLLWS 264
D + ++AIRD F+ + + +++ FF + +G+ ++VA GA +L +
Sbjct: 206 --YDVSLLKEPKDAIRDVNTFKTGWLVLVLLLVGFFGLEPLGVPVSLVAAAGALLLFAVA 263
Query: 265 RVPPEVALEKV----EWATLFFFGGLFIIVGGLVETGLIEDVGKWIVSHISSEN--EAIL 318
+ + KV W + F G++++V GL GL + +++ ++ + A L
Sbjct: 264 KKGHAINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTHYLSS-LLNQLAEQGLWAATL 322
Query: 319 MISWVSAFLSAIIDNIPFTATMIPLIKSMGGS----INVYPLWWALSLGACLGGNGTAIG 374
+++AFLS++++N+P T++ S+ GS + + +A +G+ LG T IG
Sbjct: 323 GTGFLTAFLSSVMNNMP---TVLVGALSIDGSTATGVIKEAMIYANVIGSDLGPKITPIG 379
Query: 375 ASANVVVLGIAYREGIRITFIDFLKVGMI----IMLLTVGAGSLVL 416
+ A ++ L + ++ I+IT+ + +VG++ ++ +T+ A +L L
Sbjct: 380 SLATLLWLHVLSQKNIKITWGYYFRVGIVMTIPVLFVTLAALALRL 425
>gb|AAF89641.1|AF168737_4 (AF168737) ArsB [Klebsiella oxytoca]
Length = 429
Score = 114 bits (283), Expect = 2e-24
Identities = 98/400 (24%), Positives = 189/400 (46%), Gaps = 38/400 (9%)
Query: 30 AAMLGASIMLFLKIVPWENIPEYLDL--DTILLLAGMMVIVNISRESGLFEYIAIKVARI 87
+AMLGA + L +V +IP ++ + +++I + ESG FE+ A+ V+R
Sbjct: 27 SAMLGAGLALISGVVHVGDIPVVWNIVWNATATFIAVIIISLLLDESGFFEWAALHVSRW 86
Query: 88 SKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLTPMLLYITRRMGVD---PVPYLLAEIFA 144
G + + A V+A N L+LTP+++ + +G + +++A F
Sbjct: 87 GNGRGRLLFTYIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSKGTTLAFVMAAGFI 146
Query: 145 SNIGGTATLIGDPPNIMIASAAKLSFNEFIMNMTPIAFLDLFIMVALIYLFYRREFKNVE 204
++ ++ + NI+ A L F E+ M P+ + +A+++LF+R K++
Sbjct: 147 ADTASLPLIVSNLVNIVSADFFGLGFTEYASVMVPVDIAAIIATLAMLHLFFR---KDIP 203
Query: 205 YHVDGIMNLREEEAIRDKQLFRKSVVTIAFVVLAFFLHDTIGIEPAVVALTGASILLLWS 264
D + +AI+D FR + + +++ FF+ + +GI + +A GA IL +
Sbjct: 204 PTYDLALLKAPTKAIKDPATFRTGWIVLILLLVGFFVLEPLGIPVSAIAAVGAVILFAVA 263
Query: 265 RVPPEVALEKV----EWATLFFFGGLFIIVGGLVETGLIE----------DVGKWIVSHI 310
+ + KV W + F G++++V GL GL E D G W
Sbjct: 264 KRGHAINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNVLADKGLW----- 318
Query: 311 SSENEAILMISWVSAFLSAIIDNIPFTATMIPLIKSMGGS----INVYPLWWALSLGACL 366
A L +++AFLS+I++N+P T++ S+ GS + + +A +G L
Sbjct: 319 ----AATLGTGFLTAFLSSIMNNMP---TVLVGALSIDGSTATGVFKEAMIYANVIGCDL 371
Query: 367 GGNGTAIGASANVVVLGIAYREGIRITFIDFLKVGMIIML 406
G T IG+ A ++ L + ++ + IT+ + + G+++ L
Sbjct: 372 GPKITPIGSLATLLWLHVLSQKNMTITWGYYFRTGIVMTL 411
>dbj|BAA24823.1| (AB004659) ArsB [Acidiphilium multivorum]
Length = 429
Score = 112 bits (278), Expect = 7e-24
Identities = 97/400 (24%), Positives = 188/400 (46%), Gaps = 38/400 (9%)
Query: 30 AAMLGASIMLFLKIVPWENIPEYLDL--DTILLLAGMMVIVNISRESGLFEYIAIKVARI 87
+AMLGA + L +V +IP ++ + +++I + ESG FE+ A+ V+R
Sbjct: 27 SAMLGAGLALISGVVHVGDIPVVWNIVWNATATFIAVIIISLLLDESGFFEWAALHVSRW 86
Query: 88 SKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLTPMLLYITRRMGVD---PVPYLLAEIFA 144
G + + A V+A N L+LTP+++ + +G + +++A F
Sbjct: 87 GNGRGRLLFTYIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSKGTTLAFVMAAGFI 146
Query: 145 SNIGGTATLIGDPPNIMIASAAKLSFNEFIMNMTPIAFLDLFIMVALIYLFYRREFKNVE 204
++ ++ + NI+ A L F E+ M P+ + + +++LF+R K++
Sbjct: 147 ADTASLPLIVSNLVNIVSADFFGLGFTEYASVMVPVDIAAIVATLVMLHLFFR---KDIP 203
Query: 205 YHVDGIMNLREEEAIRDKQLFRKSVVTIAFVVLAFFLHDTIGIEPAVVALTGASILLLWS 264
D + +AI+D FR + + +++ FF+ + +GI + +A GA IL +
Sbjct: 204 PTYDLALLKAPAKAIKDLATFRTGWIVLILLLVGFFVLEPLGIPVSAIAAVGAVILFAVA 263
Query: 265 RVPPEVALEKV----EWATLFFFGGLFIIVGGLVETGLIE----------DVGKWIVSHI 310
+ + KV W + F G++++V GL GL E D G W
Sbjct: 264 KRGHAIKTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNVLADKGLW----- 318
Query: 311 SSENEAILMISWVSAFLSAIIDNIPFTATMIPLIKSMGGS----INVYPLWWALSLGACL 366
A L +++AFLS+I++N+P T++ S+ GS + + +A +G L
Sbjct: 319 ----AATLGTGFLTAFLSSIMNNMP---TVLVGALSIDGSTATGVIKEAMIYANVIGCDL 371
Query: 367 GGNGTAIGASANVVVLGIAYREGIRITFIDFLKVGMIIML 406
G T IG+ A ++ L + ++ + IT+ + + G+++ L
Sbjct: 372 GPKITPIGSLATLLWLHVLSQKNMTITWGYYFRTGIVMTL 411
>sp|P37310|ARSB_ECOLI ARSENICAL PUMP MEMBRANE PROTEIN >gi|516211|emb|CAA56362.1| (X80057)
membrane-located arsenite efflux pump [Escherichia coli]
Length = 429
Score = 112 bits (277), Expect = 9e-24
Identities = 96/390 (24%), Positives = 188/390 (47%), Gaps = 18/390 (4%)
Query: 30 AAMLGASIMLFLKIVPWENIPEYLDL--DTILLLAGMMVIVNISRESGLFEYIAIKVARI 87
+A LGA + L +V +IP ++ + +++I + ESG FE+ A+ V+R
Sbjct: 27 SATLGAVLALVTGVVHPGDIPVVWNIVWNATAAFIAVIIISLLLDESGFFEWAALHVSRW 86
Query: 88 SKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLTPMLLYITRRMGVDPVPYLLAEIFASNI 147
G + + A V+A N L+LTP+++ + +G L + A I
Sbjct: 87 GNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSKGTTLAFVMAAGFI 146
Query: 148 GGTATL---IGDPPNIMIASAAKLSFNEFIMNMTPIAFLDLFIMVALIYLFYRREFKNVE 204
TA+L + + NI+ A L F E+ M P+ + + +++L++R K++
Sbjct: 147 ADTASLPLIVSNLVNIVSADFFGLGFREYASVMVPVDIAAIVATLVMLHLYFR---KDIP 203
Query: 205 YHVDGIMNLREEEAIRDKQLFRKSVVTIAFVVLAFFLHDTIGIEPAVVALTGASILLLWS 264
+ D + EAI+D F+ V + +++ FF+ + +GI + +A GA IL + +
Sbjct: 204 QNYDMALLKSPAEAIKDPATFKTGWVVLLLLLVGFFVLEPLGIPVSAIAAVGALILFVVA 263
Query: 265 RVPPEVALEKV----EWATLFFFGGLFIIVGGLVETGLIEDVGKWIVSHISSEN---EAI 317
+ + KV W + F G++++V GL GL E + V ++ ++N A
Sbjct: 264 KRGHAINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSG--VLNVLADNGLWAAT 321
Query: 318 LMISWVSAFLSAIIDNIPFTAT-MIPLIKSMGGSINVYPLWWALSLGACLGGNGTAIGAS 376
L +++AFLS+I++N+P + + S + + +A +G LG T IG+
Sbjct: 322 LGTGFLTAFLSSIMNNMPTVLVGALSIDGSTASGVIKEAMVYANVIGCDLGPKITPIGSL 381
Query: 377 ANVVVLGIAYREGIRITFIDFLKVGMIIML 406
A ++ L + ++ + I++ + + G+I+ L
Sbjct: 382 ATLLWLHVLSQKNMTISWGYYFRTGIIMTL 411
>pir||S47723 arsenite efflux pump (EC 1.-.-.-) - Escherichia coli
>gi|912466|gb|AAB18478.1| (U00039) arsF [Escherichia
coli] >gi|1789917|gb|AAC76527.1| (AE000426) arsenical
pump membrane protein [Escherichia coli K12]
Length = 436
Score = 112 bits (277), Expect = 9e-24
Identities = 96/390 (24%), Positives = 188/390 (47%), Gaps = 18/390 (4%)
Query: 30 AAMLGASIMLFLKIVPWENIPEYLDL--DTILLLAGMMVIVNISRESGLFEYIAIKVARI 87
+A LGA + L +V +IP ++ + +++I + ESG FE+ A+ V+R
Sbjct: 34 SATLGAVLALVTGVVHPGDIPVVWNIVWNATAAFIAVIIISLLLDESGFFEWAALHVSRW 93
Query: 88 SKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLTPMLLYITRRMGVDPVPYLLAEIFASNI 147
G + + A V+A N L+LTP+++ + +G L + A I
Sbjct: 94 GNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSKGTTLAFVMAAGFI 153
Query: 148 GGTATL---IGDPPNIMIASAAKLSFNEFIMNMTPIAFLDLFIMVALIYLFYRREFKNVE 204
TA+L + + NI+ A L F E+ M P+ + + +++L++R K++
Sbjct: 154 ADTASLPLIVSNLVNIVSADFFGLGFREYASVMVPVDIAAIVATLVMLHLYFR---KDIP 210
Query: 205 YHVDGIMNLREEEAIRDKQLFRKSVVTIAFVVLAFFLHDTIGIEPAVVALTGASILLLWS 264
+ D + EAI+D F+ V + +++ FF+ + +GI + +A GA IL + +
Sbjct: 211 QNYDMALLKSPAEAIKDPATFKTGWVVLLLLLVGFFVLEPLGIPVSAIAAVGALILFVVA 270
Query: 265 RVPPEVALEKV----EWATLFFFGGLFIIVGGLVETGLIEDVGKWIVSHISSEN---EAI 317
+ + KV W + F G++++V GL GL E + V ++ ++N A
Sbjct: 271 KRGHAINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSG--VLNVLADNGLWAAT 328
Query: 318 LMISWVSAFLSAIIDNIPFTAT-MIPLIKSMGGSINVYPLWWALSLGACLGGNGTAIGAS 376
L +++AFLS+I++N+P + + S + + +A +G LG T IG+
Sbjct: 329 LGTGFLTAFLSSIMNNMPTVLVGALSIDGSTASGVIKEAMVYANVIGCDLGPKITPIGSL 388
Query: 377 ANVVVLGIAYREGIRITFIDFLKVGMIIML 406
A ++ L + ++ + I++ + + G+I+ L
Sbjct: 389 ATLLWLHVLSQKNMTISWGYYFRTGIIMTL 418
>sp|P08691|ARB1_ECOLI ARSENICAL PUMP MEMBRANE PROTEIN >gi|78324|pir||B25937 arsenical
pump membrane protein - Escherichia coli plasmid R773
>gi|151858|gb|AAA21095.1| (J02591) ArsB [Plasmid R773]
Length = 429
Score = 109 bits (271), Expect = 5e-23
Identities = 91/393 (23%), Positives = 193/393 (48%), Gaps = 24/393 (6%)
Query: 30 AAMLGASIMLFLKIVPWENIPEYLDL--DTILLLAGMMVIVNISRESGLFEYIAIKVARI 87
+A LGA + L ++ +IP ++ + +++I + ESG FE+ A+ V+R
Sbjct: 27 SATLGAVLALASGVIHIADIPVVWNIVWNATATFIAVIIISLLLDESGFFEWAALHVSRW 86
Query: 88 SKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLTPMLLYITRRMGVD---PVPYLLAEIFA 144
G + + A V+A N L+LTP+++ + +G + +++A F
Sbjct: 87 GNGRGRLLFTYIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSKSTTLAFVMAAGFI 146
Query: 145 SNIGGTATLIGDPPNIMIASAAKLSFNEFIMNMTPIAFLDLFIMVALIYLFYRREFKNVE 204
S+ ++ + NI+ A KL F E+ M P+ + + +++LF+R++
Sbjct: 147 SDTASLPLIVSNLVNIVSADFFKLGFTEYASVMVPVDIAAIIATLVMLHLFFRKDIPPTY 206
Query: 205 YHVDGIMNLRE-EEAIRDKQLFRKSVVTIAFVVLAFFLHDTIGIEPAVVALTGASILLLW 263
+ L+E +AI+D FR V + +++ FF+ + +GI + +A GA++L
Sbjct: 207 ----ELARLKEPAKAIKDPATFRTGWVVLLLLLVGFFVLEPMGIPVSAIAAVGAAVLFAV 262
Query: 264 SRVPPEVALEKV----EWATLFFFGGLFIIVGGLVETGLIEDVGKWIVSHISSEN--EAI 317
++ + KV W + F G+++++ GL GL + + +++ ++ + A
Sbjct: 263 AKKGHGINTGKVLRGAPWQIVIFSLGMYLVIYGLRNAGLTDYLSD-VLNELADKGLWAAT 321
Query: 318 LMISWVSAFLSAIIDNIPFTATMIPLIKSMGGS----INVYPLWWALSLGACLGGNGTAI 373
L +++A LS+I++N+P T++ S+ GS + + +A +G LG T I
Sbjct: 322 LGTGFLTALLSSIMNNMP---TVLIGALSIDGSTATGVIKEAMIYANVIGCDLGPKITPI 378
Query: 374 GASANVVVLGIAYREGIRITFIDFLKVGMIIML 406
G+ A ++ L + ++ + IT+ + + G+++ L
Sbjct: 379 GSLATLLWLHVLSQKNMTITWGYYFRTGIVMTL 411
>pir||G83361 ArsB protein PA2278 [imported] - Pseudomonas aeruginosa (strain
PAO1) >gi|9948307|gb|AAG05666.1|AE004653_9 (AE004653)
ArsB protein [Pseudomonas aeruginosa]
Length = 427
Score = 108 bits (267), Expect = 1e-22
Identities = 102/415 (24%), Positives = 197/415 (46%), Gaps = 20/415 (4%)
Query: 7 IIALGVFISVYAAIISEKIHRTV--AAMLGASIMLFLKIVPWENIPEYLDL--DTILLLA 62
+IA +F+ +I + + +A +GA + L L V +IP ++ +
Sbjct: 2 LIAFAIFLFTLVLVIWQPRGLGIGWSASIGALLALALGSVAPGDIPTVWNIVWNATATFI 61
Query: 63 GMMVIVNISRESGLFEYIAIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLTPM 122
++VI + E+G FE+ A+ VAR + GD R+ + A VSA N L+LTP+
Sbjct: 62 AVIVISLLLDEAGFFEWAALHVARWAGGDGRRLFAFCVLLGAAVSALFANDGAALILTPI 121
Query: 123 LLYITRRMGVDPVPYLLAEIFASNIGGTATL---IGDPPNIMIASAAKLSFNEFIMNMTP 179
++ + + P L + A I +A+L + + NI+ A L F E+ M P
Sbjct: 122 VMSMLLALRFSPAATLAFVMAAGFIADSASLPLVVSNLVNIVSADYFGLGFGEYAAVMLP 181
Query: 180 IAFLDLFIMVALIYLFYRREFKNVEYHVDGIMNLREEEAIRDKQLFRKSVVTIAFVVLAF 239
+ + + + +++L++RR+ V Y ++ + R AIRD+ F + ++
Sbjct: 182 VNLVSVATSLLVLFLYFRRDLPPV-YALEQLKPPR--AAIRDRATFVVGGWMLLVLLAGL 238
Query: 240 FLHDTIGIEPAVVALTGASILLLWSR----VPPEVALEKVEWATLFFFGGLFIIVGGLVE 295
F + +G+ + VA A++LL + + L + W + F G++++V GL
Sbjct: 239 FALEPLGVPVSAVAAACAALLLAVAGRGRVISTRRVLREAPWQIVVFSLGMYLVVYGLKN 298
Query: 296 TGLIEDVGKWIVSHISSEN--EAILMISWVSAFLSAIIDNIP--FTATMIPLIKSMGGSI 351
GL D+ +++ ++ A L +SA LS++++N+P + G++
Sbjct: 299 AGL-TDLLAQLLNRLAEHGVWAAALGTGLLSAALSSVMNNMPSMLLGALSIQASDTAGAV 357
Query: 352 NVYPLWWALSLGACLGGNGTAIGASANVVVLGIAYREGIRITFIDFLKVGMIIML 406
+ +A +G LG T IG+ A ++ L + R+G+RIT+ + +VG ++ L
Sbjct: 358 R-EAMIYANVIGCDLGPKITPIGSLATLLWLHVLARKGMRITWGYYFRVGALLTL 411
>sp|P52146|ARB2_ECOLI ARSENICAL PUMP MEMBRANE PROTEIN >gi|1061417|gb|AAB09627.1| (U38947)
ArsB [Plasmid R46]
Length = 429
Score = 106 bits (263), Expect = 4e-22
Identities = 95/400 (23%), Positives = 185/400 (45%), Gaps = 38/400 (9%)
Query: 30 AAMLGASIMLFLKIVPWENIPEYLDL--DTILLLAGMMVIVNISRESGLFEYIAIKVARI 87
+A LGA + L +V +IP ++ + +++I + ESG FE+ A+ V+R
Sbjct: 27 SATLGAVLALISGVVHIGDIPVVWNIVWNATATFIAVIIISLLLDESGFFEWAALHVSRW 86
Query: 88 SKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLTPMLLYITRRMGVD---PVPYLLAEIFA 144
G + + A V+A N L+LTP+++ + +G + +++A F
Sbjct: 87 GNGRGRLLFTYIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSKGTTLAFVMAAGFI 146
Query: 145 SNIGGTATLIGDPPNIMIASAAKLSFNEFIMNMTPIAFLDLFIMVALIYLFYRREFKNVE 204
++ ++ + NI+ A L F E+ M P+ + + +++LF+R K++
Sbjct: 147 ADTASLPLIVSNLVNIVSADFFGLGFTEYASVMVPVDIAAIIATLVMLHLFFR---KDIP 203
Query: 205 YHVDGIMNLREEEAIRDKQLFRKSVVTIAFVVLAFFLHDTIGIEPAVVALTGASILLLWS 264
D + +AI+D FR + + +++ FF+ + +GI + +A GA IL +
Sbjct: 204 PTYDLALLKAPAKAIKDLATFRTGWIVLILLLVGFFVLEPLGIPVSAIAAVGAVILFAVA 263
Query: 265 RVPPEVALEKV----EWATLFFFGGLFIIVGGLVETGLIE----------DVGKWIVSHI 310
+ KV W + F G++++V GL GL E D G W
Sbjct: 264 NRGHAINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNVLADKGLW----- 318
Query: 311 SSENEAILMISWVSAFLSAIIDNIPFTATMIPLIKSMGGS----INVYPLWWALSLGACL 366
A +++AFLS+I++N+P T++ S+ GS + + +A +G L
Sbjct: 319 ----AATFGTGFLTAFLSSIMNNMP---TVLVGALSIDGSTATGVIKEAMIFANVIGCDL 371
Query: 367 GGNGTAIGASANVVVLGIAYREGIRITFIDFLKVGMIIML 406
G T IG+ A ++ L + ++ + IT+ + + G+++ L
Sbjct: 372 GPKITPIGSLATLLWLHVLSQKNMTITWGYYFRTGIVMTL 411
>sp|Q57898|Y456_METJA HYPOTHETICAL PROTEIN MJ0456 >gi|2128333|pir||H64356 hypothetical
protein MJ0456 - Methanococcus jannaschii
>gi|1499250|gb|AAB98444.1| (U67496) conserved
hypothetical protein [Methanococcus jannaschii]
Length = 352
Score = 102 bits (252), Expect = 8e-21
Identities = 97/386 (25%), Positives = 182/386 (47%), Gaps = 61/386 (15%)
Query: 37 IMLFLKIVPWENIPEYLDLDTILLLAGMMVIVNISRESGLFEYIAIKVARISKGDPMRVL 96
++L L I+ + ++ TI L +MVI+NI R++ +YI++K+ + SK R+
Sbjct: 17 LLLLLNIINPMEVFHIVEWKTIFSLFYLMVIINIMRDTKFLDYISLKILKKSK----RIF 72
Query: 97 LLFSVTTAVVSAFLDNVTTVLLLTPMLLYITRRMGV---DPVPYLLAEIFASNIGGTATL 153
+ T +S+ + N ++ ++ P+ L I R + D ++ E ++NIG T
Sbjct: 73 IALIFLTLFLSSLITNDVSLFVIIPLTLIIHRYTNMPFKDLEKLIIFEGVSANIGSGLTP 132
Query: 154 IGDPPNIMIASAAKLSFNEFIMNMTPIAFLDLFIMVALIYLFYRREFKNVEYHVDGIMNL 213
IG+P N+ + + EFI+NM P + ++ + EFK + ++ +
Sbjct: 133 IGNPQNLFLFHFYNIGTLEFIINMIPFEIFGILAILPFL------EFKKYDTKINIDIKF 186
Query: 214 REEEAIRDKQLFRKSVVTIAFVVLAFFLH-DTIGIEPAVVALTGASILLLWSRVPPEVAL 272
++E +++ V+L F + + I I P ++A +L++ RV
Sbjct: 187 KKEWIF--------YILSFILVLLCVFGYLNFIYILPLILA------ILMYKRV------ 226
Query: 273 EKVEWATLFFFGGLFIIVGGLVETGLIEDVGKWIVSHISSENEAILMISWVSAFLSAIID 332
KV++ L F LF+ + GL G+I +I S +M+ ++ LS II
Sbjct: 227 -KVDYLFLLTFIFLFVDIEGLKRIGII---------NIFSIKCGNVMLMIYASLLSQIIS 276
Query: 333 NIPFTATMIPLIKSMGGSINVYPLWWALSLGACLGGNGTAIGASANVVVLGIAYREGIRI 392
N+P T + L K+ W ++ G +GGNGT I + AN++ L ++ +R+
Sbjct: 277 NVPATVLLSHLYKN----------WLPIAYGVNIGGNGTLIASFANLITLRLS-NGNVRV 325
Query: 393 TFIDFLKVGMIIMLLTVGAGSLVLIA 418
FL +G II ++ + +VL+A
Sbjct: 326 G--RFLLIGGIIYIMHL----IVLVA 345
>gi|10955595 arsenite pump transmembrane protein ArsB [Yersinia enterocolitica]
>gi|2498159|sp|P74985|ARSB_YEREN TRANSMEMBRANE PROTEIN
OF ARSENITE PUMP >gi|1545992|gb|AAB42204.1| (U58366)
transmembrane protein of arsenite pump [Yersinia
enterocolitica] >gi|4324382|gb|AAD16859.1| (AF102990)
arsenite pump transmembrane protein ArsB [Yersinia
enterocolitica]
Length = 429
Score = 102 bits (251), Expect = 1e-20
Identities = 83/389 (21%), Positives = 185/389 (47%), Gaps = 16/389 (4%)
Query: 30 AAMLGASIMLFLKIVPWENIPEYLDL--DTILLLAGMMVIVNISRESGLFEYIAIKVARI 87
+A + A++ L ++ +IP ++ + +++I + ESG FE+ A+ V+R
Sbjct: 27 SASICAALALVSGVIHVGDIPVVWNIVWNATATFIAVIIISLLLDESGFFEWAALHVSRW 86
Query: 88 SKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLTPMLLYITRRMGVD---PVPYLLAEIFA 144
G + + A V+A N L+LTP+++ + +G + +++A F
Sbjct: 87 GNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSKRTTLAFVMAAGFI 146
Query: 145 SNIGGTATLIGDPPNIMIASAAKLSFNEFIMNMTPIAFLDLFIMVALIYLFYRREFKNVE 204
++ ++ + NI+ A +L F E+ M P+ + + +++LF+RR+ +
Sbjct: 147 ADTASLPLIVSNLVNIVSADFFRLGFTEYASVMLPVDIAAIAATLGMLHLFFRRD---IP 203
Query: 205 YHVDGIMNLREEEAIRDKQLFRKSVVTIAFVVLAFFLHDTIGIEPAVVALTGASILLLWS 264
D + AI+D FR + + +++ FF+ + +GI + +A G +L +
Sbjct: 204 ATYDVSLLKMPASAIKDPATFRAGWIVLVLLLVGFFVLEPLGIPVSAIAAVGTVVLFAVA 263
Query: 265 RVPPEVALEKV----EWATLFFFGGLFIIVGGLVETGLIEDVGKWIVSHISSEN--EAIL 318
+ + KV W + F G++++V GL GL E + +++ ++ + A
Sbjct: 264 KKGHAINTGKVLRGAPWQIVVFSLGMYLVVYGLRNAGLTEYL-SGVLNMLADKGLLAATF 322
Query: 319 MISWVSAFLSAIIDNIPFTAT-MIPLIKSMGGSINVYPLWWALSLGACLGGNGTAIGASA 377
+++AFLS++++N+P + + S + + +A +G LG T IG+ A
Sbjct: 323 GTGFLTAFLSSVMNNMPTVLVGALSIDGSTASGVIKEAMIYANVIGCDLGPKITPIGSLA 382
Query: 378 NVVVLGIAYREGIRITFIDFLKVGMIIML 406
++ L + ++ + I++ + + G+I+ L
Sbjct: 383 TLLWLHVLSQKNMTISWGYYFRTGIIMTL 411
>sp|Q57486|Y608_HAEIN HYPOTHETICAL PROTEIN HI0608 >gi|1075008|pir||I64080 probable
membrane protein HI0608 - Haemophilus influenzae
(strain Rd KW20) >gi|1573601|gb|AAC22267.1| (U32743)
conserved hypothetical protein [Haemophilus influenzae
Rd]
Length = 461
Score = 100 bits (246), Expect = 4e-20
Identities = 93/424 (21%), Positives = 192/424 (44%), Gaps = 29/424 (6%)
Query: 8 IALGVFISVYAAIISEKIHRTVAAMLGASIMLFLKIVPWENIPEYLDLDTILLLAGMMVI 67
+AL FI+V +SE +H T+ A+L + + L +V + TI L G +
Sbjct: 40 LALLAFIAVLW--LSEALHVTITALLVPLLAVALGLVSTKQALVGFADPTIFLFFGGFSL 97
Query: 68 VNISRESGLFEYIAIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLTPMLLYIT 127
L + IA K+ +++G+ ++ + TA +S ++ N T ++ P+ + I
Sbjct: 98 ATALHIQKLDKLIANKIMALARGNLFIAVIYLFLITAFLSMWMSNTATAAMMLPLAMGIL 157
Query: 128 RRMGVDP-----VPYLLAEIFASNIGGTATLIGDPPNIMIASAAKLSFNEFIMNMTPIAF 182
++ + V LL ++++IGG TL+G PPN ++AS L+F++++ PI
Sbjct: 158 SQLDREKDHNTYVFVLLGIAYSASIGGMGTLVGSPPNAIVASNLNLTFSDWLWYGLPIMI 217
Query: 183 LDLFIMVALIYLFYR--------REFKNVEYHVDGIMNLREEEAIRDKQLFRKSVVTIAF 234
+ L +M+ ++Y+ ++ + F+N+E + I+ I +F + F
Sbjct: 218 ILLPLMIGILYIIFKPKLHLNFEQTFENIEMNPMRILTFIIFPVIALTWIFSGKI--NPF 275
Query: 235 VVLAFFLHDTIGIEPAVVALTGASILLLWSRVPPEVALEKVEWATLFFFGGLFIIVGGLV 294
+ L I ++VAL A ++ + +W L FGG + L
Sbjct: 276 ISGLLGLQKNIASFDSIVALLAAIVICSTGVASWKQIQSNTDWGVLMLFGGGLTLSAVLK 335
Query: 295 ETGLIEDVGKWIVSHISSENEAI--LMISWVSAFLSAIIDNIPFTATMIPLIKSMGGSIN 352
++G + + IV I ++ + L+++ FL+ N A ++P+ S+ S+
Sbjct: 336 DSGASKILADSIVFMIDGQHFYLIGLLVAAFIIFLTEFTSNTASAALLVPIFISIAQSLG 395
Query: 353 VYPLWWALSLGACLGGNGT---AIGASANVVVLG---IAYREGIRITFIDFLKVGMIIML 406
+ + AL +G +G + + N +V G + E +++ F+ L + ++++
Sbjct: 396 MPEIGLALIIG--IGASCAFMLPVATPPNAIVFGSGQVKQSEMVKVGFL--LNLVCVVVI 451
Query: 407 LTVG 410
T+G
Sbjct: 452 ATMG 455
>pir||E81324 probable arsenical pump membrane protein Cj1187c [imported] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6968620|emb|CAB73441.1| (AL139077) putative
arsenical pump membrane protein [Campylobacter jejuni]
Length = 428
Score = 100 bits (246), Expect = 4e-20
Identities = 99/400 (24%), Positives = 190/400 (46%), Gaps = 30/400 (7%)
Query: 29 VAAMLGASIMLFLKIVPWENIPEYLDL--DTILLLAGMMVIVNISRESGLFEYIAIKVAR 86
V + LGA + ++V +++ L D+ L L G++++ G F++IA K+
Sbjct: 25 VFSSLGAFFVFIFQLVDFKDACFVFSLVWDSSLTLVGLIILSFSLEALGFFDFIASKILY 84
Query: 87 ISKG--------DPMRVLLLFSVTTAVVSAFLDNVTTVLLLTPMLLYI------TRRMGV 132
S+ +++L + +SAF N +L++TP+++ + +
Sbjct: 85 FSREKNQEKIYISTKKMMLFLLIFVFFLSAFFANDGAILIITPIIIALFSTLKDCKNHAF 144
Query: 133 DPVPYLLAEIFASNIGGTATLIGDPPNIMIASAAKLSFNEFIMNM-TPIAFLDLFIMVAL 191
+LL+ F + A +I + NI+ A+ K+ F EF NM P F+ L +V +
Sbjct: 145 ILSSFLLSLSFLCDASSNALVISNLTNIITANYFKIEFLEFAKNMFLPNFFVLLSTIVTV 204
Query: 192 IYLFYRREFKNVEYHVDGIMNLREEEAIRDKQLFRKSVVTIAFVVLAFFLHDTIGIEPAV 251
L+ R K +E+ L ++E I K LF +V + V++FF+ + I+ +
Sbjct: 205 FVLYVRVLPKRLEF------KLIKKEQISLK-LFFLCIVFLFLFVISFFIGEIFDIKISF 257
Query: 252 VALTGASIL-LLWSRVPPEVALE---KVEWATLFFFGGLFIIVGGLVETGLIEDVGKWIV 307
AL A I L+ ++ + +++ + + L F GL+++V L + G+ E + K
Sbjct: 258 FALLWAGIFWLIVLKIQGKKSIKILFEAPYGVLLFSFGLYMVVFALHKIGVSEILVK-SY 316
Query: 308 SHISSENEAILMISWVSAFLSAIIDNIPFTATMIPLIKSMGGSINVYPLW-WALSLGACL 366
+ + + I ++ +SAF S++ +N+P +K + + L +A LG +
Sbjct: 317 AFLMQDKSGIFGVALISAFGSSVFNNLPMVLIGDLALKEYFENFSFDSLMIYAHLLGVNI 376
Query: 367 GGNGTAIGASANVVVLGIAYREGIRITFIDFLKVGMIIML 406
G T IG+ A ++ LG+ R+GI I+F + K G +I L
Sbjct: 377 GPKLTPIGSLATLLWLGVLARKGINISFWQYCKFGFLITL 416
>pir||H70606 probable arsenical pump membrane protein - Mycobacterium
tuberculosis (strain H37RV) >gi|1877309|emb|CAB07152.1|
(Z92774) arsB2 [Mycobacterium tuberculosis]
Length = 413
Score = 99.8 bits (245), Expect = 5e-20
Identities = 102/431 (23%), Positives = 197/431 (45%), Gaps = 45/431 (10%)
Query: 8 IALGVFISVYAAIISEKIHR------TVAAMLGASIMLFL-KIVPWENIPEYLDLDTILL 60
+ L V + + A ++ + R AA+ A I+L + I P + + + L ++
Sbjct: 1 MTLAVALILLAVVLGFAVARPRGWPEAAAAVPAAVILLAIGAISPQQAMAQVSGLARVVA 60
Query: 61 LAG-MMVIVNISRESGLFEYIAIKVARISKGDPMRVLLLFSVTTAVVSAF-LDNVTTVLL 118
G ++V+ + + GLFE +AR S + +F+V+ A+ +A LD TV+L
Sbjct: 61 FLGAVLVLAKLCDDEGLFEAAGAAMARASAESHRLLRQVFAVSAAITAALCLD--ATVVL 118
Query: 119 LTPMLLYITRRMGVDPVPYLLAEIFASNIGGTATLIGDPPNIMIASAAKLSFNEFIMNMT 178
LTP++L RR+ PY A +N + + N++ A +SF +F + M
Sbjct: 119 LTPVVLATVRRLRTPVRPYAYATAHLANAASLLLPVSNLTNLLAYHGAGISFTKFTLLMA 178
Query: 179 PIAFLDLFIMVALIYLFYRREFKNVEYHVDGIMNLREEEAIRDKQLFRKS-------VVT 231
L VA +Y+ +R F R+ + D+Q + + +V
Sbjct: 179 ----LPWLSAVAAVYVVFRWFF------------ARDLRVVPDRQQLKPAPRLPMFVLVV 222
Query: 232 IAFVVLAFFLHDTIGIEPAVVALTGASILLLWSRVPPEVALEKVEWAT----LFFFGGLF 287
+A + F + +++G+ P AL GA++L L S ++ ++ A L F L
Sbjct: 223 VALTLGGFAVAESVGLAPTWAALAGAAVLALRSLRRGHTSVLRIARAVNVSFLVFVLALG 282
Query: 288 IIVGGLVETGLIEDVGKWIVSHISSENEAILMISWVSAFLSAIIDNIPFTATMIPLIKSM 347
++V ++ G+ + V S A+L I+ ++A L+ +++N+P T ++PL+ +
Sbjct: 283 VVVHAVMLNGMAARMS--AVLPTGSGLPALLGIAALAAVLANVVNNLPATLVLVPLV-AA 339
Query: 348 GGSINVYPLWWALSLGACLGGNGTAIGASANVVVLGIAYREGIRITFIDFLKVGMIIMLL 407
GG V A+ LG +G N T G+ +N++ G+ R + + ++ ++G+ +
Sbjct: 340 GGPAAVL----AVLLGVNIGPNLTYAGSLSNLLWRGVLRRHNVDASVGEYTRLGLCTVPA 395
Query: 408 TVGAGSLVLIA 418
+ L L A
Sbjct: 396 ALAMAVLALWA 406
>pir||B82510 transporter, NadC family VCA0025 [imported] - Vibrio cholerae
(group O1 strain N16961) >gi|9657405|gb|AAF95939.1|
(AE004346) transporter, NadC family [Vibrio cholerae]
Length = 462
Score = 99.8 bits (245), Expect = 5e-20
Identities = 95/372 (25%), Positives = 169/372 (44%), Gaps = 38/372 (10%)
Query: 8 IALGVFISVYAAII--SEKIHRTVAAMLGASIMLFLKIVPWENIPEYLDLDTILLLAGMM 65
+ LG+ + + A++ +E +H TV A+L + +F I + I L G
Sbjct: 45 VVLGISMLAFIAVLWLTEALHVTVTAILVPVMAVFFGIFETQAALNNFANSIIFLFLGGF 104
Query: 66 VIVNISRESGLFEYIAIKVARISKGD-PMRVLLLFSVTTAVVSAFLDNVTTVLLLTPMLL 124
+ GL + IA KV +++G + V +LF VT A++S ++ N T ++ P++L
Sbjct: 105 ALAAAMHHQGLDKVIADKVLAMAQGKMSVAVFMLFGVT-ALLSMWISNTATAAMMLPLVL 163
Query: 125 YITRRMGVDP-----VPYLLAEIFASNIGGTATLIGDPPNIMIASAAKLSFNEFIMNMTP 179
+ ++ D V LL ++++IGG ATL+G PPN + A+ LSF +++ P
Sbjct: 164 GVLSKVDADKQRSTYVFVLLGVAYSASIGGIATLVGSPPNAIAAAEVGLSFTDWMKFGLP 223
Query: 180 IAFLDLFIMVALIYLFYRREFKNVEYHVDGIMNLREEEAIRDKQLFRKSVVTIAFVVLAF 239
A + L + +A++Y + ++G+ L DK VVT+ L
Sbjct: 224 TAMMMLPMAIAILYFLLKPT-------LNGMFELDRAPVNWDK----GKVVTLGIFGLTV 272
Query: 240 FLHDTIGIEPAVVAL-----------TGASILLLWSRVPPEVALEK-VEWATLFFFGGLF 287
FL I P AL GA ++L ++RV ++K +W L FGG
Sbjct: 273 FL--WIFSSPINAALGGFKSFDTLVALGAILMLSFARVVHWKEIQKTADWGVLLLFGGGL 330
Query: 288 IIVGGLVETG---LIEDVGKWIVSHISSENEAILMISWVSAFLSAIIDNIPFTATMIPLI 344
+ L +TG + + +VSH+ IL+++ FL+ N A +IP+
Sbjct: 331 CLSNVLKQTGTSVFLANALSDMVSHMGI-FVVILVVATFVVFLTEFASNTASAALLIPVF 389
Query: 345 KSMGGSINVYPL 356
++ + + P+
Sbjct: 390 ATVAEAFGMSPV 401
>gb|AAC69643.1| (AF010234) ArsB [Pseudomonas aeruginosa]
Length = 425
Score = 98.7 bits (242), Expect = 1e-19
Identities = 102/416 (24%), Positives = 199/416 (47%), Gaps = 24/416 (5%)
Query: 7 IIALGVFISVYAAIISEKIHRTV--AAMLGASIMLFLKIVPWENIPEYLDL--DTILLLA 62
+IA +F+ +I + + +A +GA + L L V +IP ++ +
Sbjct: 2 LIAFAIFLFTLVLVIWQPRGLGIGWSASIGALLALALGSVAPGDIPTVWNIVWNATATFI 61
Query: 63 GMMVIVNISRESGLFEYIAIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLTPM 122
++VI + E+G FE+ A+ VA + R+ + A VSA N L+LTP+
Sbjct: 62 AVIVISLLLDEAGFFEWAALHVA-LGWRRTRRLFAFCVLLGAAVSALFANDGAALILTPI 120
Query: 123 LLYITRRMGVDPVPYLLAEIFASNIGGTATL---IGDPPNIMIASAAKLSFNEFIMNMTP 179
++ + + P L + A I +A+L + + NI+ A L F E+ M P
Sbjct: 121 VMSMLLALRFSPAATLAFVMAAGFIADSASLPLVVSNLVNIVSADYFGLGFGEYAAVMLP 180
Query: 180 IAFLDLFIMVALIYLFYRREFKNVEYHVDGIMNLREEEAIRDKQLFRKSVVTIAFVVLAF 239
+ + + + +++L++RR+ V Y ++ + R AIRD+ F + ++
Sbjct: 181 VNLVSVATSLLVLFLYFRRDLPPV-YALEQLKPPRA--AIRDRATFVVGGWMLLVLLAGL 237
Query: 240 FLHDTIGIEPAVVALTGASILLLWS---RVPPEVALEKVEWATLFFFGGLFIIVGGLVET 296
F + +G+ + VA A++LL + RV + + W + F G++++V GL
Sbjct: 238 FALEPLGVPVSAVAAACAALLLAVAGRGRVISTRRVREAPWQIVVFSLGMYLVVYGLKNA 297
Query: 297 GLIEDVGKWIVSHISSEN--EAILMISWVSAFLSAIIDNIPFTATMIPLIKSMGGSINVY 354
GL + + + +++ ++ A L +SA LS++++N+P +M+ S+ S
Sbjct: 298 GLTDLLAQ-LLNRMTEHGVWAAALGTGLLSAALSSVMNNMP---SMLLGALSIQASDTAG 353
Query: 355 P----LWWALSLGACLGGNGTAIGASANVVVLGIAYREGIRITFIDFLKVGMIIML 406
P + +A +G LG T IG+ A ++ L + R+G+RIT+ + +VG ++ L
Sbjct: 354 PVREAMIYANVIGCDLGPKITPIGSLATLLWLHVLARKGMRITWGYYFRVGALLTL 409
>gb|AAC24385.1| (U89959) Hypothetical protein [Arabidopsis thaliana]
Length = 502
Score = 98.3 bits (241), Expect = 2e-19
Identities = 66/229 (28%), Positives = 120/229 (51%), Gaps = 4/229 (1%)
Query: 8 IALGVF--ISVYAAIISEKIHRTVAAMLGASIMLFLKIVPWENIPEYLDLDTILLLAGMM 65
+A +F ++V+ ++ I RT ++ GA +M+ +++ E +DL + LL G M
Sbjct: 14 VAFAIFWILAVFPSVPFLPIGRTAGSLFGAMLMVIFQVITPEQAYAAIDLPILGLLFGTM 73
Query: 66 VIVNISRESGLFEYIAIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLTPMLLY 125
V+ + +F+Y+ ++ S+G P +L + +AV SA N T+ ++LT +L
Sbjct: 74 VVSIYLERADMFKYLGTLLSWKSRG-PKDLLCRVCLVSAVSSALFTNDTSCVVLTEFVLK 132
Query: 126 ITRRMGVDPVPYLLAEIFASNIGGTATLIGDPPNIMIASAAKLSFNEFIMNMTPIAFLDL 185
I R+ + P P+LLA ++NIG +AT IG+P N++IA +K+ F EF++ + P + +
Sbjct: 133 IARQKNLPPHPFLLALATSANIGSSATPIGNPQNLVIAVQSKIPFWEFLLGVFPAMIVGI 192
Query: 186 FIMVALIYLFYRREFKNVEYHVDGIMNLREE-EAIRDKQLFRKSVVTIA 233
+ L+ Y R + + + + N E A D Q R S T +
Sbjct: 193 TVNAMLLLGMYWRLLSDHKEDEEEVQNADSEVVAQEDVQSHRFSPATFS 241
>sp|Q58086|Y672_METJA HYPOTHETICAL PROTEIN MJ0672 >gi|2129152|pir||H64383 Na+ transporter
- Methanococcus jannaschii >gi|1591386|gb|AAB98666.1|
(U67514) membrane bound transport protein, putative
[Methanococcus jannaschii]
Length = 432
Score = 95.2 bits (233), Expect = 1e-18
Identities = 90/422 (21%), Positives = 191/422 (44%), Gaps = 20/422 (4%)
Query: 3 SELEIIALGVFISVYAAII--SEKIHRTVAAMLGASIMLFLKIVPWENIPEYLDLDTILL 60
S L I G+ I + A + E + V ++ + +FL I + Y I L
Sbjct: 21 SSLPDIYKGIVILIVAGCLWFFELLPLPVTSLAIPIMAVFLGIFNLKEALTYFAHPIIFL 80
Query: 61 LAGMMVIVNISRESGLFEYIAIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLT 120
G ++ + L ++IA K+ K L+F ++ +S ++ N + L+L
Sbjct: 81 FLGGFMLAQALKNHNLDKFIAYKLLNYGKDFKTTCFLMF-LSAYFLSMWISNTSATLILL 139
Query: 121 PMLLYITRRMGVDPVPYLLAEI-FASNIGGTATLIGDPPNIMIASAAKLSFNEFIMNMTP 179
P+ L + + +LL + ++++IGG AT+IG PPN + +S F + P
Sbjct: 140 PIALGLLHKKTGKLRDFLLLGVAYSASIGGIATIIGSPPNAIASSYLDYGFFSWFKVGFP 199
Query: 180 IAFLDLFIMVALIYLFYRREFKNVEYHVDGIMNLREEEAIRDKQLFRKSVVTIAFVVLAF 239
I+ L I +Y+++++ + + M L A + +F V+ + +++
Sbjct: 200 ISLLLFLICTLTLYIYFKKWIPKEDIAIQARMEL-SRNAYKLLVIF---VLIASLWIISD 255
Query: 240 FLHDTIGIE--PAVVALTGASILLLWSRVPPEVALEKVEWATLFFFGGLFIIVGGLVETG 297
+L + ++ +V+A+ +L +++ V +K++W TL FGG + G +V++G
Sbjct: 256 YLSEIFNVQYFDSVIAIFAIILLFVFNLVEVN-DFKKIDWGTLILFGGALCLGGVIVKSG 314
Query: 298 LIEDVGKWIVSHISSENEAIL--MISWVSAFLSAIIDNIPFTATMIPLIKSMGGSINVYP 355
+ + +++ + + +L ++ ++ L+ I N T ++P++ + I
Sbjct: 315 ANTFLSEKLIAILGNLTPIVLLFLVVTITIILTNFISNTGLTGIIVPILFGVSLGIPKEI 374
Query: 356 LWWALSLGACLGGNGTAIGASANVVVLGIAYREGIRITFIDFLKVGMIIMLLTVGAGSLV 415
L A+ + A +G N +V Y EG++ + +K+GMI+ +L+ +L
Sbjct: 375 LILAVGMSASCSFI-LPVGTPPNAIV----YSEGVKKE--EMMKIGMILSILSAAVITLY 427
Query: 416 LI 417
I
Sbjct: 428 SI 429
>pir||A75166 hypothetical protein PAB0325 - Pyrococcus abyssi (strain Orsay)
>gi|5457918|emb|CAB49408.1| (AJ248284) hypothetical
protein [Pyrococcus abyssi]
Length = 369
Score = 94.0 bits (230), Expect = 3e-18
Identities = 108/373 (28%), Positives = 174/373 (45%), Gaps = 56/373 (15%)
Query: 51 EYLDLDTILLLAGMMVIVNISRESGLFEYIAIKVARIS-KGDPMRVLLLFSVTTAVVSAF 109
++++ ++ L+ +++ SG+F +AI++AR S +G +R++LL TA SAF
Sbjct: 20 QFVNWGSLFLITSLIIASKGLELSGVFTSLAIRLARGSMRGISIRLILL----TAFSSAF 75
Query: 110 LDNVTTVLLLTPMLLYITRRMGVDPVPYLLAEI-FASNIGGTATLIGDPPNIMIASAAKL 168
+ N T VL+ TP+++ + R V+ VP L+ + ++NIG + T +G+P NI+I L
Sbjct: 76 IMNDTAVLVFTPLVVSLGRIAEVN-VPRLVTLVAISANIGSSLTPMGNPQNIIIWRHYNL 134
Query: 169 SFNEFIMNMTPIAFLDLFIMVALIYLFYRREFKNVEYHVDGIMNLREEEAIRDKQLFRKS 228
EFI M P L L I++A +L R E K +E G+ K LF S
Sbjct: 135 GILEFIKGMLPFTLLWLLILLAFAWL-ERGEVKLLEVPGVGVR----------KDLFFAS 183
Query: 229 VVTIAFVVLAFFLHDTIGIEPAVVALTGASILLLWSRVPPEVALEKVEWATLFFFGGLFI 288
+ L FL ++ ++ AL IL L V+ L F I
Sbjct: 184 AFLLG---LDLFLGK---LDMSLFALVFTIILFL-----------VVDRYVLLSFDIALI 226
Query: 289 IVGGLVETGLIEDVGKWIVSHISSENEAILMISWVSAFLSAIIDNIPFTATMIPLIKSMG 348
L+ + E I + + + VS F+S I N+P TA +I
Sbjct: 227 PTFALIFSNFAE-----ISELVKPKIVGYKLTFLVSLFMSQFISNVPATAILI------- 274
Query: 349 GSINVYPLWWALSLGACLGGNGTAIGASANVVVLGIAYREGIRITFIDFLKVGMI-IMLL 407
NV W LSLG LGGNGT I + AN++ L I+ + + DF + ++ IM+
Sbjct: 275 -HSNV--PWLPLSLGVNLGGNGTVISSLANLIALRIS-----GVKWRDFHRYSLLYIMVA 326
Query: 408 TVGAGSLVLIARY 420
T+ + L+ R+
Sbjct: 327 TLVTFGIFLLLRH 339
>pir||C71131 hypothetical protein PH0816 - Pyrococcus horikoshii
>gi|3257226|dbj|BAA29909.1| (AP000003) 368aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 368
Score = 92.1 bits (225), Expect = 1e-17
Identities = 78/338 (23%), Positives = 146/338 (43%), Gaps = 38/338 (11%)
Query: 47 ENIPEYLDLDTILLLAGMMVIVNISRESGLFEYIAIKVARISKGDPMRVLLLFSVTTAVV 106
+ P +D I L+A ++++ SG+F ++ + +S G R+ + +T A
Sbjct: 35 QRTPGLIDWRNISLIASLILVSRGLELSGIFTRLSSYLISVSGGSGRRLAFILLLTIAFS 94
Query: 107 SAFLDNVTTVLLLTPMLLYITRRMGVDPVPYLLAEIFASNIGGTATLIGDPPNIMIASAA 166
S+ + N T +L+ P+++ I++ D ++ A+NIG T IG+P NI+I ++
Sbjct: 95 SSIIMNDTAMLIFIPLIVTISKVSEEDLSSLVVLSAIAANIGSALTPIGNPQNIIIWNSY 154
Query: 167 KLSFNEFIMNMTPIAFLDLFIMVALIYLFYRREFKNVEYHVDGIMNLREEEAIRDKQLFR 226
+ F+ F++ M P L L +++ L YL + + + E I + +
Sbjct: 155 AIPFHSFVLEMLPFVLLWLLLLLFLAYLIFNDKIERKELPPVNI----NTSFLWTSMILL 210
Query: 227 KSVVTIAFVVLAFFLHDTIGIEPAVVALTGASILLLWSRVPPEVALEKVEWATLFFFGGL 286
+T A A + T I V L G +L +W L F +
Sbjct: 211 VGDITFAQGGKALW---TFPITFGVFLLIGREVLF------------GFDWGLLLMFIFI 255
Query: 287 FIIVGGLVETGLIEDVGKWIVSHISSENEAILMISWVSAFLSAIIDNIPFTATMIPLIKS 346
F+ G + ++ G +S N + + SAFLS ++ N+P T +
Sbjct: 256 FVDFGEIAH--ILSSSG------VSFPNSGVKLF-LTSAFLSQLVSNVPATILL------ 300
Query: 347 MGGSINVYPLWWALSLGACLGGNGTAIGASANVVVLGI 384
+N W +L+ G +GG G +G+ AN++ + I
Sbjct: 301 ----LNEGKDWISLAAGVNIGGTGLIVGSLANLIAIRI 334
>pir||F70302 transporter (Pho87 family) - Aquifex aeolicus
>gi|2982784|gb|AAC06409.1| (AE000670) transporter (Pho87
family) [Aquifex aeolicus]
Length = 446
Score = 92.1 bits (225), Expect = 1e-17
Identities = 111/424 (26%), Positives = 189/424 (44%), Gaps = 49/424 (11%)
Query: 11 GVFISVYAAI--ISEKIHRTVAAMLGASIMLFLKIVPWENIPEYLDLDTILLLAGMMVIV 68
G+ I + AAI I+E + V A+L + L + + Y I L G V+
Sbjct: 30 GIAILLLAAILWITEALPLPVTALLIPVSGVLLGVFDVKTALSYFAHPLIFLFFGGFVLA 89
Query: 69 NISRESGLFEYIAIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLTPMLLYI-- 126
+ + EYIA K+ +++G + + L + T+++S ++ N +T ++ P+ L I
Sbjct: 90 VALSKYQIDEYIAHKIVSVAQGKFLPSVFLLMLATSLISMWISNTSTTAMMLPLALGILA 149
Query: 127 ----TRRMGVDPVPYLLAEIFASNIGGTATLIGDPPNIMIASAAKLSFNEFIMNMTPIAF 182
T R V P LL +++++GG TL+G PPN + A LSF +++ P+ F
Sbjct: 150 GVRETEREKVFPF-VLLGIAYSASVGGIGTLVGSPPNGIAAGILGLSFPDWLKFGIPV-F 207
Query: 183 LDLF-IMVALIYLFYR----------REFKNVEYHVDGIMNLREEEAIRDKQLFRKSVVT 231
L LF ++ A+++L +R +E K E+ ++ L +F K +
Sbjct: 208 LILFPLLFAILFLVFRPTSDLKVERVQEIK-FEFTPQRVLVLLIFLFTALAWIFSKKIAP 266
Query: 232 IAFVVLAFFLHDTIGIEPAVVALTGASILLLWSRVPPEVALEKVEWATLFFFGGLFIIVG 291
I F V +F DT+ AVVAL LL W V E V W TL FGG + G
Sbjct: 267 I-FEVKKYF--DTVVALLAVVALF-IFRLLDWRDVK-----EGVSWGTLLLFGGGIALSG 317
Query: 292 GLVETGLIEDVGKWIVSHISSENEAILMISWV--SAFLSAIIDNIPFTATMIPLIKSMGG 349
+ +TG + + + +V + + +++ V FL+ ++ N TA + P++ S
Sbjct: 318 IMKKTGTAKFISQELVDVLHGLPTFLFLLTIVLFVIFLTELMSNTATTALIAPILFSTAQ 377
Query: 350 SIN------VYPLWWALSLGACLGGNGTAIGASANVVVLGIAYREGIRITFIDFLKVGMI 403
I V P A S L + N +V G Y I ++VG+I
Sbjct: 378 MIGKPPEMLVIPAAVAASCAFML-----PVATPPNAIVYGTGY-----IKQSQMMRVGLI 427
Query: 404 IMLL 407
+ ++
Sbjct: 428 LNIV 431
>sp|P75788|YBIR_ECOLI HYPOTHETICAL 41.2 KDA PROTEIN IM OMPX-MOEB INTERGENIC REGION
>gi|7466797|pir||B64819 probable membrane protein ybiR -
Escherichia coli >gi|1787039|gb|AAC73905.1| (AE000184)
orf, hypothetical protein [Escherichia coli K12]
>gi|4062385|dbj|BAA35499.1| (D90719) Hypothetical
protein MJ0456 [Escherichia coli]
>gi|4062392|dbj|BAA35506.1| (D90720) Hypothetical
protein MJ0456 [Escherichia coli]
Length = 372
Score = 91.3 bits (223), Expect = 2e-17
Identities = 95/387 (24%), Positives = 173/387 (44%), Gaps = 38/387 (9%)
Query: 32 MLGASIMLFLKIVPWENIPEYLDLDTILLLAGMMVIVNISRESGLFEYIAIKVARISKGD 91
++G + F+ P ++ P +D TI+ L+G+M++ SG F+ + K+ R +
Sbjct: 20 LVGIGLSFFVPFAP-KSWPAAIDWHTIITLSGLMLLTKGVELSGYFDVLGRKMVRRFATE 78
Query: 92 PMRVLLLFSVTTAVVSAFLDNVTTVLLLTPMLLYITRRMGVDPVPYLLAEIFASNIGGTA 151
R+ + + A++S FL N + ++ P+ + + R + ++ E A N G
Sbjct: 79 -RRLAMFMVLAAALLSTFLTNDVALFIVVPLTITLKRLCEIPVNRLIIFEALAVNAGSLL 137
Query: 152 TLIGDPPNIMIASAAKLSFNEFIMNMTPIAFLDLFIMVALIYLFYRREFKNVEYHVDGIM 211
T IG+P NI+I + LSF FI M P+A + ++ L + + K ++YH G+
Sbjct: 138 TPIGNPQNILIWGRSGLSFAGFIAQMAPLAGAMMLTLLLLCWCCF--PGKAMQYHT-GV- 193
Query: 212 NLREEEAIRDKQLFRKSVVTIAFVVLAFFLHDTIGIEPAVVALTGASILLLWSRVPPEVA 271
+ + + ++ + I F+ F + G+ + A LL RV
Sbjct: 194 ---QTPEWKPRLVWSCLGLYIVFLTALEFKQELWGL-----VIVAAGFALLARRV----- 240
Query: 272 LEKVEWATLFFFGGLFIIVGGLVETGLIEDVGKWIVSHISSENEAILMISWVSAF-LSAI 330
+ V+W L F +FI V L + ++ V VSH+S W++A LS +
Sbjct: 241 VLSVDWTLLLVFMAMFIDVHLLTQLPALQGV-LGNVSHLSEPG------LWLTAIGLSQV 293
Query: 331 IDNIPFTATMIPLIKSMGGSINVYPLWWALSLGACLGGNGTAIGASANVVVLGIAYREGI 390
I N+P T ++ + L WA++ +GG G G+ AN++ L +A I
Sbjct: 294 ISNVPSTILLLNYVPPS------LLLVWAVN----VGGFGLLPGSLANLIALRMANDRRI 343
Query: 391 RITFIDFLKVGMIIMLLTVGAGSLVLI 417
F + M++ VG LV++
Sbjct: 344 WWRF-HLYSIPMLLWAALVGYVLLVIL 369
>pir||C69205 sodium/dicarboxylate or sulfate cotransporter - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2621879|gb|AAB85290.1| (AE000857)
sodium/dicarboxylate or sulfate cotransporter
[Methanobacterium thermoautotrophicum]
Length = 443
Score = 84.7 bits (206), Expect = 2e-15
Identities = 93/424 (21%), Positives = 180/424 (41%), Gaps = 32/424 (7%)
Query: 9 ALGVFISVYAAIISEKIHRTVAAMLGASIMLFLKIVPWENIPEYLDLDTILLLAGMMVIV 68
AL + + +E + V +++ + + +EN + L+ G ++
Sbjct: 20 ALALLVFAVTMWATEAVPLAVTSLIILFAQPLIGVESFENAVIGFANPILFLMIGGFIMA 79
Query: 69 NISRESGLFEYIAIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLTPMLLYITR 128
R+SGL + + P R L + +T ++SA+++NV +L P++ I
Sbjct: 80 EAIRKSGLAQRFTYYLLGRLGTSPERGLFVSIFSTGLLSAWIENVVAFAMLLPIIKEIVD 139
Query: 129 RMGVDPVP---------YLLAEIFASNIGGTATLIGDPPNIMIASAAKLSFNEFIMNMTP 179
MG +L F S GG T IG PN+M A+ + F +++ P
Sbjct: 140 IMGCSEPEKGKSNYAKAMILGASFGSLAGGFGTEIGTAPNLMAAAYTSIPFLNWMIFGLP 199
Query: 180 IAFLDLFIMVALIYLFYRREFKNVEYHVDGIMNLREE---EAIRDKQLFRKSVVTIAFVV 236
++ L + L+ + E + +E + D ++ R RD++L S + F +
Sbjct: 200 LSIAMLLVTWFLLMRIFPSEVRALE-NGDALIGERIRMMGSMSRDEKL---SAGILLFAI 255
Query: 237 LAFFLHDTIGIEPAVVALTGASILLLWSRVPPEVALEKVEWATLFFFGGLFIIVGGLVET 296
L + GI V+L A + + + + A + ++W + FFGG + L++T
Sbjct: 256 LLWVTAGFTGINSYSVSLIAAVMFIFAGVITWKDAQKNIDWGLVVFFGGALSLGSALLKT 315
Query: 297 GLIEDVGKWIVSHISSENEAI---LMISWVSAFLSAIIDNIPFTATMIPLIKSMGGS--- 350
G + +V + S+ + L++ V+ ++ ++ NI +A ++PL ++ +
Sbjct: 316 GAAAWIIDKLVGMLGSDPSTVIVMLVLMAVAVIITQVMSNIALSAILVPLSVTLASAQHQ 375
Query: 351 -INVY--PLWWALSLGACL--GGNGTAIGASANVVVLGIAYREGIRITFIDFLKVGMIIM 405
I VY P+ A SL L A+ + V L R GI I + VG+I+
Sbjct: 376 PIGVYAVPVAIACSLSFMLPMADPTVAMAYGSGYVKLRDIPRAGIPI-----IAVGIILT 430
Query: 406 LLTV 409
+L +
Sbjct: 431 VLVI 434
>pir||G81156 transporter, NadC family NMB0792 [imported] - Neisseria
meningitidis (group B strain MD58)
>gi|7226025|gb|AAF41205.1| (AE002433) transporter, NadC
family [Neisseria meningitidis MC58]
Length = 471
Score = 84.3 bits (205), Expect = 3e-15
Identities = 94/433 (21%), Positives = 184/433 (41%), Gaps = 34/433 (7%)
Query: 8 IALGVFISVYAAIISEKIHRTVAAMLGASIMLFLKIVPWENIPEYLDLDT--ILLLAGMM 65
IAL +F++ A +E +H TV A++ + + L + D I + G
Sbjct: 57 IALLIFVA--ALWFTEAVHITVTALMVPILAVVLGFPDMDIKKAMADFSNPIIYIFFGGF 114
Query: 66 VIVNISRESGLFEYIAIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLTPMLLY 125
+ L IA+ + R+S+G+ +L+ + TA +S ++ N T ++ P+ +
Sbjct: 115 ALATALHMQRLDRKIAVSLLRLSRGNMKVAVLMLFLVTAFLSMWISNTATAAMMLPLAMG 174
Query: 126 ITRRMGVDP-----VPYLLAEIFASNIGGTATLIGDPPNIMIASAAKLSFNEFIMNMTPI 180
+ + + V LL + ++IGG TL+G PPN++ A A L F ++ P+
Sbjct: 175 MLSHLDQEKEHKTYVFLLLGIAYCASIGGLGTLVGSPPNLIAAKALNLDFVGWMKLGLPM 234
Query: 181 AFLDLFIMVALIYLFYRREF-KNVEYHVDGI-MNLREEEAIRDKQLFRKSVVTIAFVVLA 238
L L +M+ +Y+ + + VE + I L A+ +F + T A + +
Sbjct: 235 MLLILPLMLLSLYVILKPNLNERVEIKAESIPWTLHRVIAL---LIF---LATAAAWIFS 288
Query: 239 FFLHDTIGIE--PAVVALTGASILLLWSRVPPEVALEKVEWATLFFFGGLFIIVGGLVET 296
+ GI V+AL+ A ++++ + +W L FGG + L +
Sbjct: 289 SKIKTAFGISNPDTVIALSAAVAVVVFGVAQWKEVARNTDWGVLMLFGGGISLSTLLKTS 348
Query: 297 GLIEDVGKWIVSHISSENE--AILMISWVSAFLSAIIDNIPFTATMIPLIKSMGGSINV- 353
G E +G+ + + S IL+++ FL+ N A ++P+ + + +
Sbjct: 349 GASEALGQQVAATFSGAPAFLVILIVAAFIIFLTEFTSNTASAALLVPIFSGIAMQMGLP 408
Query: 354 -YPLWWALSLGACLGGNGTAIGASANVVVLGIAYREGIRITFIDFLKVGMIIMLLTVGAG 412
L + + +GA + N +V G I + + VG+++ +L V
Sbjct: 409 EQVLVFVIGIGASCAFM-LPVATPPNAIVFGTGL-----IKQREMMNVGILLNILCV--- 459
Query: 413 SLVLIARYGGGIL 425
VL+A + +L
Sbjct: 460 --VLVALWAYAVL 470
>pir||A81948 probable transmembrane transport protein NMA1003 [imported] -
Neisseria meningitidis (group A strain Z2491)
>gi|7379705|emb|CAB84272.1| (AL162754) putative
transmembrane transport protein [Neisseria meningitidis
Z2491]
Length = 471
Score = 84.3 bits (205), Expect = 3e-15
Identities = 96/433 (22%), Positives = 184/433 (42%), Gaps = 34/433 (7%)
Query: 8 IALGVFISVYAAIISEKIHRTVAAMLGASIMLFLKIVPWENIPEYLDLDT--ILLLAGMM 65
IAL +F++ A +E +H TV A++ + + L + D I + G
Sbjct: 57 IALLIFVA--ALWFTEAVHITVTALMIPILAVVLGFPDMDIKKAMADFSNPIIYIFFGGF 114
Query: 66 VIVNISRESGLFEYIAIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLTP---- 121
+ L IA+ + R+S+G +L+ + TA +S ++ N T ++ P
Sbjct: 115 ALATALHMQRLDRKIAVSLLRLSRGSMKAAVLMLFLVTAFLSMWISNTATAAMMLPLAMG 174
Query: 122 MLLYITRRMGVDPVPYLLAEI-FASNIGGTATLIGDPPNIMIASAAKLSFNEFIMNMTPI 180
ML ++ R ++L I + ++IGG TL+G PPN++ A A L F ++ P+
Sbjct: 175 MLSHLDREKERKTYVFVLLGIAYCASIGGLGTLVGSPPNLIAAKALNLDFVGWMKLGLPM 234
Query: 181 AFLDLFIMVALIYLFYRREF-KNVEYHVDGI-MNLREEEAIRDKQLFRKSVVTIAFVVLA 238
L L +M+ +Y+ + + VE + I L A+ +F + T A + +
Sbjct: 235 MLLILPLMLLSLYVILKPNLNERVEIKAESIPWTLHRVIAL---LIF---LATAAAWIFS 288
Query: 239 FFLHDTIGIE--PAVVALTGASILLLWSRVPPEVALEKVEWATLFFFGGLFIIVGGLVET 296
+ GI V+AL+ A ++++ + +W L FGG + L +
Sbjct: 289 SKIKTAFGISNPDTVIALSAAVAVVVFGVAQWKEVARNTDWGVLMLFGGGISLSTLLKTS 348
Query: 297 GLIEDVGKWIVSHISSENE--AILMISWVSAFLSAIIDNIPFTATMIPLIKSMGGSINV- 353
G E +G+ + + S IL+++ FL+ N A ++P+ + + +
Sbjct: 349 GASEALGQQVAATFSGAPAFLVILIVAAFIIFLTEFTSNTASAALLVPIFSGIAMQMGLP 408
Query: 354 -YPLWWALSLGACLGGNGTAIGASANVVVLGIAYREGIRITFIDFLKVGMIIMLLTVGAG 412
L + + +GA + N +V G I + + VG+++ +L V
Sbjct: 409 EQVLVFVIGIGASCAFM-LPVATPPNAIVFGTGL-----IKQREMMNVGILLNILCV--- 459
Query: 413 SLVLIARYGGGIL 425
VL+A + +L
Sbjct: 460 --VLVALWAYAVL 470
>sp|P52137|YFJV_ECOLI PUTATIVE ARSENICAL PUMP MEMBRANE PROTEIN
Length = 338
Score = 80.8 bits (196), Expect = 3e-14
Identities = 79/322 (24%), Positives = 147/322 (45%), Gaps = 36/322 (11%)
Query: 104 AVVSAFLDNVTTVLLLTPMLLYITRRMGVDPVPYLLAEIFASNIGGTATL---IGDPPNI 160
A V A N L+LTP+++ + +G L + A I TA+L + + NI
Sbjct: 12 AAVDALFANDGAALILTPIVIAMLIALGFSQGTTLAFVMAAGFIADTASLPLIVSNLVNI 71
Query: 161 MIASAAKLSFNEFIMNMTPIAFLDLFIMVALIYLFYRREFKNVEYHVDGIMNLREEEAIR 220
+ A LSF ++ M + + + ++YLF+RR Y V + AI+
Sbjct: 72 VSADFFGLSFAQYASVMISVDAAAIAATLIMLYLFFRRVIP-ATYXVSLLKT--PASAIK 128
Query: 221 DKQLFRKSVVTIAFVVLAFFLHDTIGIEPAVVALTGASILLLWSRVPPEVALEKV----E 276
D FR + + +++ FF + GI + +A GA++L + ++ + KV
Sbjct: 129 DLATFRAGWIVLLLLLVGFFFLEPQGILVSAIAAAGAAVLFVVAKRGHSINTGKVLRGAP 188
Query: 277 WATLFFFGGLFIIVGGLVETG----------LIEDVGKWIVSHISSENEAILMISWVSAF 326
W + F G++I+V GL G L+ D G W A +++AF
Sbjct: 189 WQIVIFSLGMYIVVYGLRNAGFTEYLSGVLNLLADKGLW---------AATFGTGFLTAF 239
Query: 327 LSAIIDNIPFTATMIPLIKSMGGS----INVYPLWWALSLGACLGGNGTAIGASANVVVL 382
LS++++N+P T++ S+ GS + + +A +G LG T IG+ A ++ L
Sbjct: 240 LSSVMNNMP---TVLIGALSIDGSTATGVVKEAMIYANVIGCDLGPKITPIGSLATLLWL 296
Query: 383 GIAYREGIRITFIDFLKVGMII 404
+ ++ + IT+ + + G+++
Sbjct: 297 HVLAQKNMTITWGYYFRTGIVM 318
>pir||B70069 arsenical pump membrane protein homolog ywrK - Bacillus subtilis
>gi|1929338|emb|CAB07801.1| (Z93767) similar to ArsB
integral membrane protein presumably containing the
arsenate-arsenite-antimony transmembrane channel
[Bacillus subtilis] >gi|2636128|emb|CAB15620.1| (Z99122)
similar to arsenical pump membrane protein [Bacillus
subtilis]
Length = 442
Score = 79.6 bits (193), Expect = 6e-14
Identities = 86/415 (20%), Positives = 180/415 (42%), Gaps = 36/415 (8%)
Query: 25 IHRTVAAMLGASIMLFLKIVPWENIPEYLDLDT---ILLLAGMMVIVNISRESGLFEYIA 81
++ + A GA ++L V ++ E T + +LA M++ + + G F ++A
Sbjct: 18 LNEAIPATFGALMVLLCGSVSLADLGEIGTKVTGASVTILATMIMAIALE-SFGFFYWVA 76
Query: 82 IKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLTPMLLYITRRMGV---DPVPYL 138
K+ + SKG +++ L ++ +++ FL+N ++L+ TP+LL + + +G+ PYL
Sbjct: 77 AKLLQQSKGSGIKLFWLTNLLCFLMTIFLNNDGSILITTPILLLVLKYLGLKKHQKAPYL 136
Query: 139 LAEIFASNIGGTATLIGDPPNIMIASAAKLSFNEFIMNMTPIAFLDLFIMVALIYLFY-- 196
L+ + + + + N++ + M + + L M L+++F+
Sbjct: 137 LSGVLIATASSAPIGVSNIVNLISLKIIGMDLYLHTAMMFVPSMMGLIFMTCLLFMFFYK 196
Query: 197 --RREFKNVEYHVDGIMNLR------EEEAIRDKQLFRKSVVTIAFVVL---AFFLHDTI 245
+ ++ H + + R + ++ + + +AFV L + F
Sbjct: 197 RLPKSLPDIPGHFQSLRHRRYHPLHSPSAPLPERNQTKIMLFVLAFVFLVRMSLFAASYT 256
Query: 246 GIEPAVVALTGASILLLWS----RVPPEVALEKVEWATLFFFGGLFIIVGGLVETGLIED 301
GI +VA+ G+ ILL W + P L K W F +++++ GL G E
Sbjct: 257 GISVPLVAVIGSFILLSWRWIYFKTSPRDLLYKSPWHIFIFAFTMYVLIYGLHNIGFTEL 316
Query: 302 VGKWIVSHISSENEAILMISWVS-AFLSAIIDNIP------FTATMIPLIKSMGGSINVY 354
+ + +S S +S + S + +N P FT T + L S
Sbjct: 317 LVSYFEPVVSGSLAHATFASGISTSVFSNLFNNHPALMISTFTLTEMTLNPS-----TTK 371
Query: 355 PLWWALSLGACLGGNGTAIGASANVVVLGIAYREGIRITFIDFLKVGMIIMLLTV 409
++ A +G+ +G +G A ++ + I + I++ +++K +II+ LTV
Sbjct: 372 IIYLANIIGSDIGSLLLPMGTLATLIWMHILKQHDESISWGEYIKTTIIIIPLTV 426
>gb|AAD12976.1| (AF078135) unknown [Leptospira borgpetersenii]
Length = 464
Score = 77.6 bits (188), Expect = 2e-13
Identities = 94/384 (24%), Positives = 165/384 (42%), Gaps = 40/384 (10%)
Query: 57 TILLLAGMMVIVNISRESGLFEYIAIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTV 116
+I+L G V+ ++GL + A ++ R +VLL F TT +S ++ N T
Sbjct: 97 SIILFLGGFVLAKACVKTGLDRFFANRIIRKFGVKSHQVLLGFMFTTGFISMWMSNTATT 156
Query: 117 LLLTPMLLYITRRMGVDPVPYLLAEI----FASNIGGTATLIGDPPNIMIASAAK----- 167
++ + + R + + P+ A I FA+NIGG T IG PPNI+ +
Sbjct: 157 SMMIALSFPLLRVLP-EKEPFRKALILGIPFAANIGGVGTPIGSPPNIIAMGILRQQGIV 215
Query: 168 LSFNEFIMNMTP-IAFLDLFIMVALIYLFYRREFKNVEYHVDGIMNLREEEAIRDKQLFR 226
+ F ++ P + L LF + L+ LF +++ +D ++ +E E FR
Sbjct: 216 IPFGTWMFFAVPLVVVLILFAWILLMKLFPQKD------SLDLVVEFQEPERGMKSFSFR 269
Query: 227 KSVVTIAFVVLAFFLHDTIGIEPAVVALTGASILLLWSRVPPEVALEKVEWATLFFFGGL 286
+ + V+ +F + G+ VVAL IL + E + ++W+ L G
Sbjct: 270 VTSMIFLGTVVLWFTENLHGVPAGVVALL-PLILFPMFGILNEKDINSLDWSVLILISGG 328
Query: 287 FIIVGGLVETGLIEDVGKW---IVSHISSENEAILMISW---VSAFLSAIIDNIPFTATM 340
I G ++G+ G W I+ HI+ AI ++ + ++ LS + N T +
Sbjct: 329 IGIGVGFQQSGM----GPWFSGILKHIAKPEYAISVLFFLCVLTLLLSTFMSNTAATNLL 384
Query: 341 IPLIKSMGGSI----NVYPLWWALSLGACLGGNGTAIGASANVVVLGIAYREGIRITFID 396
+P + NVY L + LG L + A+ + IAY G I D
Sbjct: 385 VPFAFPFSAILFPGSNVYLL--EVCLGIALSAS-LAMSLPVSTPPNAIAYSVG-GIEIKD 440
Query: 397 FLKVGMIIMLLTVGAGSLVLIARY 420
+ G+ I + G +V+++ Y
Sbjct: 441 MICAGLPIGIF----GLIVVLSSY 460
>pir||S43561 YCR37C homolog K08E5.2 - Caenorhabditis elegans
Length = 526
Score = 76.9 bits (186), Expect = 4e-13
Identities = 94/456 (20%), Positives = 185/456 (39%), Gaps = 74/456 (16%)
Query: 21 ISEKIHRTVAAMLGASIMLFLKIVPWENIPEYLDLDTILLLAGMMVIVNISRESGLFEYI 80
+SE + V AML + + ++ + DT L G +++ + L E +
Sbjct: 49 MSEVMPLAVTAMLPVVLFPLVGVLDANTTAKEYMNDTNFLFIGGLIMAAAVEKCDLHERV 108
Query: 81 AIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLTPMLLYITR------------ 128
A+ V R +P ++L F TA++S+F+ N T ++ P+ + +
Sbjct: 109 ALSVLRCVGSEPKWIMLGFMTVTALLSSFISNTATTAMMVPIGQSVVQQLISSFQHHPTN 168
Query: 129 ----RMGVDPVP--YLLAEIFASNIGGTATLIGDPPNIMIASA---------AKLSFNEF 173
R+G + +L+ FA+NIGGT T G P N+++ L++ +
Sbjct: 169 GERGRLGCKKMATGLVLSICFAANIGGTGTATGTPSNLVMLGQLSALFPKVDGSLNYVTW 228
Query: 174 IMNMTPIAFLDLFIMVALIYLFYRREFKNVEYHVDGIMNLREEEAIRDKQLFRKSVVTIA 233
I P+ L LF+ + F+ R+ + V ++ R E R KSV
Sbjct: 229 IFFAYPLMLLCLFVAWMTLVSFFLRDAPEKDEAVTEMLKTRYNELPR-MTYAEKSVFVCF 287
Query: 234 FVVLAFFLHDTIGIEP-------------AVVALTGASILLLWSRVPPEVAL-------- 272
++L+ ++ G+ P A A+ A +L + P++A
Sbjct: 288 CILLSLWVFRNPGVVPGFGVFFKKGAYTDATSAMIVAFLLFVLPSERPDLATYIKKEDLK 347
Query: 273 ------------EKVEWATLFFFGGLFIIVGGLVETGLIEDVGKWIVSHISSENEAILMI 320
E W+ + GG F + G+ E+GL +G S S E+ + ++
Sbjct: 348 KRGCLMDWKTMQETFPWSVVLLLGGGFALAAGVKESGLSLLIGN---SLSSIEHLPLWIL 404
Query: 321 SWVSAFLSAIIDNI---PFTATM-IPLIKSMGGSINVYPLWWALSLGACLGGNGT---AI 373
++ ++ +I NI TA++ +P++ ++ +P + L L L + +
Sbjct: 405 QLLTMLIAMVITNICSNTVTASIFVPIVATLAQRAGHHP--FTLMLPTTLASSFAFIFPV 462
Query: 374 GASANVVVLGIAYREGIRITFIDFLKVGMIIMLLTV 409
G N +V G + + F+ + + + +++LTV
Sbjct: 463 GTPPNAIVFGSGMVKVSDMAFVGGI-ISLELLVLTV 497
>sp|Q21339|YM22_CAEEL HYPOTHETICAL 58.7 KD PROTEIN K08E5.2 IN CHROMOSOME III
>gi|3878357|emb|CAA83225.1| (Z30974) contains similarity
to Pfam domain: PF00939 (Sodium:sulfate symporter
transmembrane region), Score=250.8, E-value=6e-72,
N=1~cDNA EST yk250f6.5 comes from this gene
[Caenorhabditis elegans]
Length = 534
Score = 76.9 bits (186), Expect = 4e-13
Identities = 94/456 (20%), Positives = 185/456 (39%), Gaps = 74/456 (16%)
Query: 21 ISEKIHRTVAAMLGASIMLFLKIVPWENIPEYLDLDTILLLAGMMVIVNISRESGLFEYI 80
+SE + V AML + + ++ + DT L G +++ + L E +
Sbjct: 57 MSEVMPLAVTAMLPVVLFPLVGVLDANTTAKEYMNDTNFLFIGGLIMAAAVEKCDLHERV 116
Query: 81 AIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTVLLLTPMLLYITR------------ 128
A+ V R +P ++L F TA++S+F+ N T ++ P+ + +
Sbjct: 117 ALSVLRCVGSEPKWIMLGFMTVTALLSSFISNTATTAMMVPIGQSVVQQLISSFQHHPTN 176
Query: 129 ----RMGVDPVP--YLLAEIFASNIGGTATLIGDPPNIMIASA---------AKLSFNEF 173
R+G + +L+ FA+NIGGT T G P N+++ L++ +
Sbjct: 177 GERGRLGCKKMATGLVLSICFAANIGGTGTATGTPSNLVMLGQLSALFPKVDGSLNYVTW 236
Query: 174 IMNMTPIAFLDLFIMVALIYLFYRREFKNVEYHVDGIMNLREEEAIRDKQLFRKSVVTIA 233
I P+ L LF+ + F+ R+ + V ++ R E R KSV
Sbjct: 237 IFFAYPLMLLCLFVAWMTLVSFFLRDAPEKDEAVTEMLKTRYNELPR-MTYAEKSVFVCF 295
Query: 234 FVVLAFFLHDTIGIEP-------------AVVALTGASILLLWSRVPPEVAL-------- 272
++L+ ++ G+ P A A+ A +L + P++A
Sbjct: 296 CILLSLWVFRNPGVVPGFGVFFKKGAYTDATSAMIVAFLLFVLPSERPDLATYIKKEDLK 355
Query: 273 ------------EKVEWATLFFFGGLFIIVGGLVETGLIEDVGKWIVSHISSENEAILMI 320
E W+ + GG F + G+ E+GL +G S S E+ + ++
Sbjct: 356 KRGCLMDWKTMQETFPWSVVLLLGGGFALAAGVKESGLSLLIGN---SLSSIEHLPLWIL 412
Query: 321 SWVSAFLSAIIDNI---PFTATM-IPLIKSMGGSINVYPLWWALSLGACLGGNGT---AI 373
++ ++ +I NI TA++ +P++ ++ +P + L L L + +
Sbjct: 413 QLLTMLIAMVITNICSNTVTASIFVPIVATLAQRAGHHP--FTLMLPTTLASSFAFIFPV 470
Query: 374 GASANVVVLGIAYREGIRITFIDFLKVGMIIMLLTV 409
G N +V G + + F+ + + + +++LTV
Sbjct: 471 GTPPNAIVFGSGMVKVSDMAFVGGI-ISLELLVLTV 505
>gb|AAD52193.1|AF144879_32 (AF144879) unknown [Leptospira interrogans]
Length = 464
Score = 73.4 bits (177), Expect = 5e-12
Identities = 90/380 (23%), Positives = 164/380 (42%), Gaps = 32/380 (8%)
Query: 57 TILLLAGMMVIVNISRESGLFEYIAIKVARISKGDPMRVLLLFSVTTAVVSAFLDNVTTV 116
+I+L G V+ ++GL + A ++ R +VLL F TT +S ++ N T
Sbjct: 97 SIVLFLGGFVLAKACVKTGLDRFFANRIIRRFGVKSHQVLLGFMFTTGFISMWMSNTATT 156
Query: 117 LLLTPMLLYITRRMGVDPVPYLLAEI----FASNIGGTATLIGDPPNIMIASAAK----- 167
++ L + +M + P+ A I FA+NIGG T IG PPNI+ +
Sbjct: 157 SMMIA-LSFPMLQMLPEKEPFRKALILGIPFAANIGGVGTPIGSPPNIIAMGILRQEGIV 215
Query: 168 LSFNEFIMNMTPIAF-LDLFIMVALIYLFYRREFKNVEYHVDGIMNLREEEAIRDKQLFR 226
+SF ++ P+ L LF + L+ LF +++ ++ ++ +E E FR
Sbjct: 216 VSFGTWMFFAVPLVIVLILFAWLLLMKLFPQKDL------LELVVEFQEPEEGTKSFSFR 269
Query: 227 KSVVTIAFVVLAFFLHDTIGIEPAVVALTGASILLLWSRVPPEVALEKVEWATLFFFGGL 286
+ VL +F + GI VVAL + ++ + E + ++W+ L G
Sbjct: 270 ITTAIFFGTVLLWFTENLHGIPAGVVALLPLILFPVFG-ILNEKDINSLDWSVLLLIAGG 328
Query: 287 FIIVGGLVETGLIEDVGKWIVSHISSEN--EAILMISWVSAFLSAIIDNIPFTATMIPLI 344
I G ++G+ +++ I E + ++ ++ LS + N T ++P
Sbjct: 329 IGIGVGFQQSGMKFWFSEFLKPIIKPEYSVSVLFLLCVLALLLSTFMSNTAATNLLVPFA 388
Query: 345 KSMGGSI----NVYPLWWALSLGACLGGNGTAIGASANVVVLGIAYREGIRITFIDFLKV 400
+ + NVY L + LG L + A+ + IAY G D ++
Sbjct: 389 FPLSTIVLPESNVYLL--EVCLGIALSAS-LAMSLPVSTPPNAIAYSVG-GFEIKDMIQA 444
Query: 401 GMIIMLLTVGAGSLVLIARY 420
G+ I +L G ++++A Y
Sbjct: 445 GLPIGIL----GLILVLAGY 460
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.328 0.144 0.417
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 142604062
Number of Sequences: 2977
Number of extensions: 5689968
Number of successful extensions: 20132
Number of sequences better than 1.0e-10: 61
Number of HSP's better than 0.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 37
Number of HSP's that attempted gapping in prelim test: 19797
Number of HSP's gapped (non-prelim): 100
length of query: 425
length of database: 189,106,746
effective HSP length: 54
effective length of query: 371
effective length of database: 156,788,448
effective search space: 58168514208
effective search space used: 58168514208
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (21.7 bits)
S2: 166 (69.1 bits)