BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB1115 (graD-2) DE:glucose-1-phosphate thymidylyltransferase
(graD-2)
(419 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||G75020 glucose-1-phosphate thymidylyltransferase (grad-2) P... 847 0.0
pir||E71207 probable glucose-1-phosphate thymidylyltransferase -... 749 0.0
pir||A69079 glucose-1-phosphate thymidylyltransferase homolog - ... 385 e-106
pir||D64437 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.... 356 2e-97
emb|CAB57558.1| (Y18930) glucose-1-phosphate thymidylyltransfera... 336 3e-91
gb|AAK41040.1| Sugar phosphate nucleotydyl transferase [Sulfolob... 336 3e-91
gb|AAG18651.1| (AE004970) glucose-1-phosphate thymidylyltransfer... 308 7e-83
pir||F72591 probable sugar phosphate transferase APE1202 - Aerop... 210 3e-53
pir||A75098 glucose-1-phosphate thymidylyltransferase (grad-3) P... 190 3e-47
gb|AAK41974.1| Sugar phosphate nucleotydyl transferase [Sulfolob... 189 4e-47
gi|11497938 glucose-1-phosphate thymidylyltransferase (graD-2) [... 186 5e-46
pir||F71151 probable glucose-1-phosphate thymidylyltransferase -... 185 1e-45
emb|CAB57473.1| (Y18930) glucose-1-phosphate thymidylyltransfera... 179 5e-44
gb|AAK41126.1| Sugar phosphate nucleotydyl transferase [Sulfolob... 179 5e-44
pir||G72325 glucose-1-phosphate thymidylyltransferase - Thermoto... 176 4e-43
pir||S76366 hypothetical protein - Synechocystis sp. (strain PCC... 175 7e-43
gb|AAG18650.1| (AE004970) glucose-1-phosphate thymidylyltransfer... 171 1e-41
gb|AAD28517.1|AF126354_3 (AF126354) BlmD [Streptomyces bluensis] 170 2e-41
emb|CAA07386.1| (AJ006985) StrD [Streptomyces glaucescens] 167 3e-40
pir||A75596 probable glucose-1-phosphate thymidylyltransferase -... 165 8e-40
pir||T48866 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.... 162 5e-39
pir||T46521 probable dTDP-1-glucose synthase [imported] - Strept... 162 5e-39
gb|AAD13545.1| (AF080235) NDP-hexose synthetase homolog [Strepto... 162 7e-39
sp|P08075|STRD_STRGR GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (... 162 7e-39
pir||A26984 strD protein - Streptomyces griseus 160 3e-38
gb|AAF59934.1| (AF237895) dTDP-D-glucose synthase [Streptomyces ... 160 3e-38
pir||T30872 dNDP-glucose synthase - Streptomyces viridochromogen... 159 4e-38
pir||T51105 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.... 159 6e-38
pir||E72229 UDP-N-acetylglucosamine pyrophosphorylase - Thermoto... 157 2e-37
gb|AAG19459.1| (AE005038) glucose-1-phosphate thymidylyltransfer... 156 4e-37
pir||G75164 mannose-1-phosphate guanyltransferase PAB0317 - Pyro... 154 1e-36
pir||S58687 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.... 153 2e-36
emb|CAB88884.1| (AL353861) putative mannose-1-phosphate guanyltr... 153 3e-36
gb|AAF00210.1|AF164960_6 (AF164960) dNDP-glucose synthetase [Str... 152 7e-36
pir||S66080 UDP-N-acetylglucosamine pyrophosphorylase gcaD - Bac... 150 4e-35
emb|CAC12604.1| (AL445067) mannose-1-phosphate guanyltransferase... 148 8e-35
sp|P14192|GCAD_BACSU UDP-N-ACETYLGLUCOSAMINE PYROPHOSPHORYLASE (... 146 3e-34
pir||C71177 probable mannose-1-phosphate guanyltransferase - Pyr... 146 4e-34
pir||C70354 UDP-N-acetylglucosamine pyrophosphorylase - Aquifex ... 145 1e-33
gb|AAK40653.1| Sugar phosphate nucleotydyl transferase [Sulfolob... 143 5e-33
pir||A72589 probable glucose-1-phosphate thymidylyltransferase A... 140 3e-32
gb|AAF60300.1|AF234177_1 (AF234177) GDP-mannose pyrophosphorylas... 140 3e-32
gb|AAB50923.1| (L47163) glucose-1-phosphate thymidylyltransferas... 138 9e-32
pir||G69101 mannose-1-phosphate guanyltransferase - Methanobacte... 138 9e-32
pir||T41209 mannose-1-phosphate guanyltransferase - fission yeas... 138 9e-32
emb|CAB58292.1| (AL121851) mannose-1-phosphate guanyltransferase... 138 1e-31
gi|6320148 mannose-1-phosphate guanyltransferase, GDP-mannose py... 137 2e-31
gb|AAA69677.1| (U24437) mannose-1-phosphate guanyltransferase [S... 136 6e-31
gb|AAC39498.1| (U89991) mannose-1-phosphate guanylyltransferase ... 136 6e-31
gb|AAC64912.1| (AF030300) putative GDP-mannose pyrophosphorylase... 135 8e-31
gb|AAC64911.1| (AF030299) putative GDP-mannose pyrophosphorylase... 135 1e-30
dbj|BAA34807.1| (AB020596) GDP-mannose pyrophosphorylase [Candid... 135 1e-30
dbj|BAB03784.1| (AP001507) UDP-N-acetylglucosamine pyrophosphory... 134 1e-30
pir||T42371 probable mannose-1-phosphate guanylyltransferase (EC... 134 2e-30
sp|P17114|GLMU_ECOLI UDP-N-ACETYLGLUCOSAMINE PYROPHOSPHORYLASE (... 134 2e-30
pir||H75070 sugar-phosphate nucleotydyl transferase PAB0645 - Py... 134 2e-30
emb|CAA25784.1| (X01631) Eco urf 1 protein [Escherichia coli] 133 3e-30
gb|AAD01737.1| (AF022716) GDP-mannose pyrophosphorylase [Solanum... 133 3e-30
pir||B72041 udp-glcnac pyrophosphorylase - Chlamydophila pneumon... 133 4e-30
emb|CAB79775.1| (AL161577) GDP-mannose pyrophosphorylase like pr... 133 4e-30
pir||A71095 probable sugar-phosphate nucleotydyl transferase - P... 132 5e-30
pir||T01007 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13... 131 2e-29
sp|P43889|GLMU_HAEIN UDP-N-ACETYLGLUCOSAMINE PYROPHOSPHORYLASE (... 131 2e-29
sp|P57139|GLMU_BUCAI UDP-N-ACETYLGLUCOSAMINE PYROPHOSPHORYLASE (... 131 2e-29
pir||S76785 hypothetical protein - Synechocystis sp. (strain PCC... 130 4e-29
dbj|BAB07043.1| (AP001518) glucose-1-phosphate thymidylyltransfe... 130 4e-29
sp|Q50986|GLMU_NEIGO UDP-N-ACETYLGLUCOSAMINE PYROPHOSPHORYLASE (... 130 4e-29
pir||D82036 UDP-N-acetylglucosamine pyrophosphorylase VC2762 [im... 129 8e-29
pir||H81244 UDP-N-acetylglucosamine pyrophosphorylase NMB0038 [i... 129 8e-29
pir||T47698 mannose-1-phosphate guanylyltransferase-like protein... 128 1e-28
pir||A70363 mannose-1-phosphate guanyltransferase - Aquifex aeol... 127 3e-28
dbj|BAA77382.1| (AB020570) GDP-mannose pyrophosphorylase [Candid... 126 4e-28
pir||S76009 hypothetical protein - Synechocystis sp. (strain PCC... 125 7e-28
pir||G82023 UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.... 125 1e-27
gb|AAF52089.1| (AE003605) CG1129 gene product [alt 1] [Drosophil... 125 1e-27
pir||G81500 UDP-N-acetlyglucosamine pyrophosphorylase GlmU-relat... 123 3e-27
pir||T32900 hypothetical protein C42C1.5 - Caenorhabditis elegan... 122 6e-27
gb|AAG18686.1| (AE004973) glucose-1-phosphate thymidylyltransfer... 122 8e-27
gb|AAG18702.1| (AE004975) glucose-1-phosphate thymidylyltransfer... 122 1e-26
pir||E70622 probable udp-n-acetylglucosamine pyrophosphorylase -... 121 2e-26
pir||A82952 glucosamine-1-phosphate acetyltransferase/ N-acetylg... 121 2e-26
gb|AAK40709.1| Sugar phosphate nucleotydyl transferase [Sulfolob... 117 3e-25
pir||C64605 UDP-N-acetylglucosamine pyrophosphorylase - Helicoba... 116 5e-25
pir||F81276 probable sugar-phosphate nucleotide transferase Cj13... 115 1e-24
gi|11431484 GDP-mannose pyrophosphorylase B [Homo sapiens] 114 2e-24
pir||A71909 udp-n-acetylglucosamine pyrophosphorylase - Helicoba... 114 2e-24
gi|7019397 GDP-mannose pyrophosphorylase B [Homo sapiens] >gi|50... 113 3e-24
dbj|BAB14882.1| (AK024319) unnamed protein product [Homo sapiens] 113 3e-24
pir||F71491 probable UDP-glcnac pyrophosphorylase - Chlamydia tr... 112 7e-24
pir||F81650 UDP-N-acetylglucosamine pyrophosphorylase GlmU-relat... 111 2e-23
pir||B71146 probable glucose-1 phosphate transferase - Pyrococcu... 108 1e-22
pir||G72455 probable glucose-1-phosphate thymidylyltransferase A... 105 1e-21
gb|AAK41261.1| Sugar phosphate nucleotydyl transferase [Sulfolob... 104 3e-21
pir||C82720 UDP-N-acetylglucosamine pyrophosphorylase XF1140 [im... 104 3e-21
pir||B75008 glucose-1-phosphate thymidylyltransferase (grad-1) P... 103 3e-21
gb|AAK42616.1| Sugar phosphate nucleotydyl transferase [Sulfolob... 102 7e-21
sp|P39629|SPSI_BACSU SPORE COAT POLYSACCHARIDE BIOSYNTHESIS PROT... 102 7e-21
pir||E75473 UDP-N-acetylglucosamine pyrophosphorylase - Deinococ... 102 7e-21
pir||C69815 glucose-1-phosphate cytidylyltransferase (EC 2.7.7.3... 101 1e-20
pir||S75920 hypothetical protein - Synechocystis sp. (strain PCC... 99 9e-20
gi|10956341 pXO1-94 [Bacillus anthracis] >gi|7474335|pir||F59102... 99 1e-19
dbj|BAB07082.1| (AP001518) spore coat polysaccharide synthesis (... 99 1e-19
gb|AAA62081.1| (L10328) similar to Bacillus subtilis tms; simila... 98 1e-19
gb|AAD31893.2|AF144042_1 (AF144042) dTDP-glucose synthase [Strep... 98 1e-19
sp|Q58730|YD34_METJA PUTATIVE UTP--GLUCOSE-1-PHOSPHATE URIDYLYLT... 97 4e-19
gb|AAG23610.1|AF244661_1 (AF244661) glucose-1-phosphate thymidyl... 96 6e-19
sp|P75124|GALU_MYCPN UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERAS... 95 1e-18
gb|AAA62180.1| (M92842) tms [Listeria monocytogenes] 94 2e-18
pir||H70446 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7... 94 3e-18
dbj|BAB05135.1| (AP001512) mannose-1-phosphate guanyltransferase... 94 3e-18
pir||T45492 N-acetylglucosamine-1-phosphate uridyltransferase [i... 93 5e-18
pir||E81354 UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.... 93 5e-18
sp|Q05852|GTAB_BACSU UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERAS... 92 8e-18
sp|P39122|GLGC_BACSU GLUCOSE-1-PHOSPHATE ADENYLYLTRANSFERASE (AD... 90 3e-17
sp|P55464|RFBA_RHISN PROBABLE GLUCOSE-1-PHOSPHATE THYMIDYLYLTRAN... 90 3e-17
pir||A70978 probable rmlA2 protein - Mycobacterium tuberculosis ... 89 7e-17
dbj|BAA84594.1| (AB032523) glucose-1-phosphate thymidyltransfera... 89 1e-16
pir||G81287 probable sugar-phosphate nucleotidyltransferase Cj14... 89 1e-16
dbj|BAA91460.1| (AK000999) unnamed protein product [Homo sapiens] 88 2e-16
gb|AAF81069.1|AF223364_4 (AF223364) mannose-1-phosphate-guanyltr... 88 2e-16
gb|AAC78674.1| (AF094575) glucose-1-phosphate thimidylyl transfe... 87 4e-16
gb|AAD19913.1| (AF105113) glucose-1-phosphate thymidylyl transfe... 87 4e-16
gb|AAD22341.1|AC006955_27 (AC006955) putative GDP-mannose pyrop... 87 4e-16
gb|AAF73461.1|AF264025_12 (AF264025) putative dTDP-1-glucose syn... 87 4e-16
gi|11497858 glucose-1-phosphate thymidylyltransferase (graD-1) [... 86 6e-16
gb|AAC38757.1| (AF030373) glucose-1-phosphate thymidyl transfera... 86 8e-16
gb|AAD10181.1| (AF026471) Cps2L [Streptococcus pneumoniae] 86 8e-16
gb|AAF58116.1| (AE003809) CG8207 gene product [Drosophila melano... 86 8e-16
pir||T39403 probable mannose-1-phosphate gaunyl transferase - fi... 86 8e-16
gb|AAC44969.1| (U09239) glucose-1-phosphate thymidyl transferase... 86 8e-16
gb|AAD31799.1|AF128273_2 (AF128273) TDP-glucose synthase homolog... 85 1e-15
emb|CAB95915.1| (AL359989) putative UDP-N-acetylglucosamine pyro... 85 2e-15
sp|O08326|GLGC_BACST GLUCOSE-1-PHOSPHATE ADENYLYLTRANSFERASE (AD... 85 2e-15
gb|AAD22456.1|AF116284_2 (AF116284) unknown [Pseudomonas aerugin... 85 2e-15
gb|AAC68682.1| (AF079762) alpha-D-glucose-1-phosphate thymidylyl... 84 2e-15
gb|AAF01820.1|AF187532_16 (AF187532) putative dTDP-glucose synth... 84 2e-15
emb|CAB65204.1| (AJ007311) RmlA protein [Legionella pneumophila] 84 3e-15
emb|CAB89282.1| (AJ277601) glucose-1-phosphate adenylyltransfera... 84 3e-15
emb|CAC01394.1| (AJ131360) glucose-1-phosphate thymidyltransfera... 84 3e-15
emb|CAB88923.1| (AL353862) putative nucleotide phosphorylase [St... 83 4e-15
gb|AAD38517.1|AF135422_1 (AF135422) GDP-mannose pyrophosphorylas... 83 7e-15
pir||D83570 probable nucleotidyl transferase PA0597 [imported] -... 83 7e-15
pir||G64763 hypothetical protein b0359 - Escherichia coli >gi|17... 80 4e-14
gb|AAC46169.1| (AF017435) glmU-like gene product [Methylobacteri... 74 3e-12
pir||B72403 glucose-1-phosphate adenylyltransferase - Thermotoga... 74 3e-12
gb|AAD55285.1|AC008263_16 (AC008263) Similar to gb|AF135422 GDP-... 73 6e-12
gb|AAF21085.1|AC013258_23 (AC013258) putative GDP-mannose pyroph... 73 6e-12
gb|AAF60647.1| (AC006780) contains similarity to Pfam families P... 73 8e-12
sp|P42817|GCAD_BACCL UDP-N-ACETYLGLUCOSAMINE PYROPHOSPHORYLASE (... 72 1e-11
>pir||G75020 glucose-1-phosphate thymidylyltransferase (grad-2) PAB1115 -
Pyrococcus abyssi (strain Orsay)
>gi|5459119|emb|CAB50605.1| (AJ248288)
glucose-1-phosphate thymidylyltransferase (graD-2)
[Pyrococcus abyssi]
Length = 419
Score = 847 bits (2164), Expect = 0.0
Identities = 419/419 (100%), Positives = 419/419 (100%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPFVDEFIIIVKYMKEKII 60
MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPFVDEFIIIVKYMKEKII
Sbjct: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPFVDEFIIIVKYMKEKII 60
Query: 61 ETLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLLHVY 120
ETLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLLHVY
Sbjct: 61 ETLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLLHVY 120
Query: 121 KKTKANAALVVKKFDDLSQLGMVKTEGGYVREIVEKPGNVGGLANLGIYIFNPDVFEFIE 180
KKTKANAALVVKKFDDLSQLGMVKTEGGYVREIVEKPGNVGGLANLGIYIFNPDVFEFIE
Sbjct: 121 KKTKANAALVVKKFDDLSQLGMVKTEGGYVREIVEKPGNVGGLANLGIYIFNPDVFEFIE 180
Query: 181 RTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKTKLKHDI 240
RTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKTKLKHDI
Sbjct: 181 RTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKTKLKHDI 240
Query: 241 RGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDNCHIGN 300
RGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDNCHIGN
Sbjct: 241 RGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDNCHIGN 300
Query: 301 AVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTITANLRHDNRTIKVEIKGKLEDSG 360
AVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTITANLRHDNRTIKVEIKGKLEDSG
Sbjct: 301 AVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTITANLRHDNRTIKVEIKGKLEDSG 360
Query: 361 RRKLGAIIGHNVKTGINVTIYPGRKIGSGALVGPGVIVDKNIPPNVLVVAKQEKIVKEI 419
RRKLGAIIGHNVKTGINVTIYPGRKIGSGALVGPGVIVDKNIPPNVLVVAKQEKIVKEI
Sbjct: 361 RRKLGAIIGHNVKTGINVTIYPGRKIGSGALVGPGVIVDKNIPPNVLVVAKQEKIVKEI 419
>pir||E71207 probable glucose-1-phosphate thymidylyltransferase - Pyrococcus
horikoshii >gi|3258369|dbj|BAA31052.1| (AP000007) 419aa
long hypothetical glucose-1-phosphate
thymidylyltransferase [Pyrococcus horikoshii]
Length = 419
Score = 749 bits (1914), Expect = 0.0
Identities = 358/416 (86%), Positives = 392/416 (94%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPFVDEFIIIVKYMKEKII 60
MKAV+LAAGKGERLRPLTDDRPKPILK+ANKPIIEYILENLDPFVDEFII+VKY KEKII
Sbjct: 1 MKAVILAAGKGERLRPLTDDRPKPILKIANKPIIEYILENLDPFVDEFIIVVKYKKEKII 60
Query: 61 ETLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLLHVY 120
ETLGDEFHGKPITYV Q +EEGTA+AIYSAKD I +EEFFAINGDIYFEQEAIRGLLH Y
Sbjct: 61 ETLGDEFHGKPITYVVQGDEEGTARAIYSAKDAIIDEEFFAINGDIYFEQEAIRGLLHTY 120
Query: 121 KKTKANAALVVKKFDDLSQLGMVKTEGGYVREIVEKPGNVGGLANLGIYIFNPDVFEFIE 180
+K KA+ +VVKKF++LSQLG+V+ + V++I+EKPG + G ANLGIYIFN +VF+FIE
Sbjct: 121 RKMKADGGIVVKKFENLSQLGLVEVKNNLVKKIIEKPGKMEGFANLGIYIFNSEVFDFIE 180
Query: 181 RTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKTKLKHDI 240
T++SERGEYEITDTIN+MI G+++ YFEY GFWSDIGRPWDLLEVNEYILKTKLKH+I
Sbjct: 181 ETEKSERGEYEITDTINIMIERGKRIVYFEYKGFWSDIGRPWDLLEVNEYILKTKLKHNI 240
Query: 241 RGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDNCHIGN 300
RGTVEEGATIIPPVEIGEGT+VRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDNCHIGN
Sbjct: 241 RGTVEEGATIIPPVEIGEGTIVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDNCHIGN 300
Query: 301 AVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTITANLRHDNRTIKVEIKGKLEDSG 360
AVE+KNSIIMDNSNAPHLNYVGDSI+GENTNLGAGTITANLRHDN+T+KVEIKG LEDSG
Sbjct: 301 AVEVKNSIIMDNSNAPHLNYVGDSIIGENTNLGAGTITANLRHDNKTVKVEIKGNLEDSG 360
Query: 361 RRKLGAIIGHNVKTGINVTIYPGRKIGSGALVGPGVIVDKNIPPNVLVVAKQEKIV 416
RRKLGAIIGHNVKTGINV+IYPGRKIGSGALVGPGVIVDKNIPP VLVVAKQEK+V
Sbjct: 361 RRKLGAIIGHNVKTGINVSIYPGRKIGSGALVGPGVIVDKNIPPGVLVVAKQEKMV 416
>pir||A69079 glucose-1-phosphate thymidylyltransferase homolog -
Methanobacterium thermoautotrophicum (strain Delta H)
>gi|2622712|gb|AAB86062.1| (AE000918)
glucose-1-phosphate thymidylyltransferase homolog
[Methanobacterium thermoautotrophicum]
Length = 423
Score = 385 bits (979), Expect = e-106
Identities = 201/423 (47%), Positives = 277/423 (64%), Gaps = 7/423 (1%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENL-DPFVDEFIIIVKYMKEKI 59
M+AV+L AG+G R+RPLT RPK +L VA KPI++Y ++ L D V + ++I Y +E +
Sbjct: 1 MQAVILTAGEGTRMRPLTLTRPKTMLPVAGKPILQYSVDALRDNGVHDIVMITGYHEEAV 60
Query: 60 IETLGD-EFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLLH 118
GD G ITYV Q E GTA AI A + I++E F +NGDI + + L+
Sbjct: 61 RSHFGDGSGSGVNITYVRQEERLGTAHAIGQASELIDDE-FIVLNGDIITDPGLMGDLIG 119
Query: 119 VYKKTKANAALVVKKFDDLSQLGMVKTEGGYVREIVEKPG---NVGGLANLGIYIFNPDV 175
Y + K +V+++ D S G+VK EG VREI+EKPG G L N GIY+F+P V
Sbjct: 120 SYHERKPETLMVLREVPDPSSFGVVKVEGDRVREIIEKPGPDAGAGNLINTGIYVFSPAV 179
Query: 176 FEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKTK 235
F++IERT S RGEYEITDTI + + D V W D+GRPW+LLE +E ++K
Sbjct: 180 FDYIERTPLSRRGEYEITDTIMMQVRDDLPVRAIISDRDWIDVGRPWELLEASERLMKD- 238
Query: 236 LKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDN 295
L+ + G VE+G TI PV IGEGT++RSG+YI GPV IG+NC IGPN ++R +T IGD
Sbjct: 239 LEDSVEGDVEDGVTIHGPVAIGEGTIIRSGTYIQGPVYIGRNCDIGPNSYLRAHTCIGDG 298
Query: 296 CHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTITANLRHDNRTIKVEIKGK 355
IGNAVE+KNSIIMD +N HL+YVGDS++G N N+ AGT ANLR D+ +++ +K
Sbjct: 299 VSIGNAVEVKNSIIMDGTNINHLSYVGDSVIGMNCNIAAGTNIANLRFDDGPVRMVVKDD 358
Query: 356 LEDSGRRKLGAIIGHNVKTGINVTIYPGRKIGSGALVGPGVIVDKNIPPNVLVVAKQEKI 415
+ ++GRRKLGA+ G VKTGIN + PG K+G + +G G ++ +++P + LV+ +QE
Sbjct: 359 VVETGRRKLGAVFGDGVKTGINSSFNPGVKVGKDSCIGAGCVISRDVPSDRLVILRQEHT 418
Query: 416 VKE 418
E
Sbjct: 419 TME 421
>pir||D64437 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) -
Methanococcus jannaschii >gi|1591746|gb|AAB99104.1|
(U67553) glucose-1-phosphate thymidylyltransferase
(strD) [Methanococcus jannaschii]
Length = 408
Score = 356 bits (905), Expect = 2e-97
Identities = 192/422 (45%), Positives = 272/422 (63%), Gaps = 18/422 (4%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPFVDEFIIIVKYMKEKII 60
M A++L AGKGERLRPLT++RPKP++ +A KPI+++I+E ++ VD +IVKY KEKI+
Sbjct: 1 MDAIILCAGKGERLRPLTENRPKPMIPIAGKPILQHIIEKVEDLVDNIYLIVKYKKEKIV 60
Query: 61 ETLGDEFHGKP-ITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLLHV 119
D F P I ++ Q E +GT +A+ +AKDY+++E F INGDI FE + L +
Sbjct: 61 ----DYFKNHPKIKFLEQGEIDGTGQAVLTAKDYVDDE-FLVINGDIIFEDDLEEFLKYK 115
Query: 120 YKKTKANAALVVKKFDDLSQLGMVKTEG-GYVREIVEKPGNV-GGLANLGIYIFNPDVFE 177
Y A+ VK+ + G+V + + E+ EKP N L N GIY F+ +FE
Sbjct: 116 Y-------AVAVKEVKNPENFGVVVLDDENNIIELQEKPENPKSNLINAGIYKFDKKIFE 168
Query: 178 FIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKTKLK 237
IE+T+ SERGE E+TD I +I + KV + +G+W+D+GRPWD+LE N+Y+L K+
Sbjct: 169 LIEKTKISERGERELTDAIKHLIKE-EKVKGIKLNGYWNDVGRPWDILEANKYLLD-KIN 226
Query: 238 HDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDNCH 297
DI+G +EE I V I EG +V++ S I GP I K +GP +IRPYT + +N
Sbjct: 227 TDIKGKIEENVVIKGEVIIEEGAIVKANSVIEGPAIIKKGAVVGPLAYIRPYTVLMENTF 286
Query: 298 IGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTITANLRHDNRTIKVEIKGKLE 357
+GN+ E+K SIIM N+ PHL+YVGDSI+GEN N G TITANLR D++ +KV IK K
Sbjct: 287 VGNSSEVKASIIMKNTKIPHLSYVGDSIIGENCNFGCNTITANLRFDDKPVKVNIKSKRV 346
Query: 358 DSGRRKLGAIIGHNVKTGINVTIYPGRKIGSGALVGPGVIVDKNIPPNVLVVAKQEKIVK 417
+S RKLG I+G NVKTGI V+ PG K+GS +G ++D++I N V + E I +
Sbjct: 347 ES-VRKLGVIMGDNVKTGIQVSFMPGVKVGSNCWIGASCLIDRDIESNTFVYKRDELIFR 405
Query: 418 EI 419
++
Sbjct: 406 KL 407
>emb|CAB57558.1| (Y18930) glucose-1-phosphate thymidylyltransferase [Sulfolobus
solfataricus]
Length = 407
Score = 336 bits (853), Expect = 3e-91
Identities = 179/405 (44%), Positives = 260/405 (64%), Gaps = 18/405 (4%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPFVDEFIIIVKYMKEKII 60
MKAVVLAAGKGERL P+T RPKP + V P+I + L ++++ II++ +
Sbjct: 1 MKAVVLAAGKGERLEPITHTRPKPFVPVLETPLILRHIRILKKYINKIIIVINSNHKDYF 60
Query: 61 ETLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIE-EEEFFAINGDIYFEQEAIRGLLHV 119
+T+ + ++ V Q E +GTA A+ +A+ Y+E +EEF I GD+ FE++A+ +++
Sbjct: 61 KTI------EGVSLVEQTEGKGTAAALRAAEKYLEGDEEFLVIYGDLLFEEDALDKIVNT 114
Query: 120 YKKTKANAALVVKKFDDLSQLGM-VKTEGGYVREIVEKPGNV-GGLANLGIYIFNPDVFE 177
A++ ++ +D + G+ VK + IVEKP N + N GIY F D+F
Sbjct: 115 -----EGEAILARESEDPRKFGVIVKDSENRLVRIVEKPENPPSNIINAGIYKFTYDIFS 169
Query: 178 FIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKTKLK 237
+I++ S RGE+E+TD +NL+ G KV Y+G W DIGRPWDL+E N+ +L +
Sbjct: 170 YIDKISLSSRGEFELTDAVNLI---GNKVKVVTYNGIWLDIGRPWDLIEANKVLLDKEKD 226
Query: 238 HDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDNCH 297
++ G +EE I V I +G +++SG+YI GPV IGKN IGPN +IRPY+ IG N
Sbjct: 227 RNL-GVIEENVKIKGKVVIEDGVIIKSGTYIEGPVYIGKNSVIGPNAYIRPYSVIGSNVK 285
Query: 298 IGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTITANLRHDNRTIKVEIKGKLE 357
+G EIK S+IM+N+ PHL+YVGDS++ E N GAGTITANLR D +KV IK +
Sbjct: 286 VGAFNEIKESVIMENAKIPHLSYVGDSVICEGVNFGAGTITANLRFDEEEVKVNIKNERV 345
Query: 358 DSGRRKLGAIIGHNVKTGINVTIYPGRKIGSGALVGPGVIVDKNI 402
SGR+KLGAI+G +V+TGINV+I PG KIG+ A + PG +VD+++
Sbjct: 346 SSGRKKLGAIVGAHVRTGINVSILPGVKIGAYAWIYPGAVVDRDV 390
>gb|AAK41040.1| Sugar phosphate nucleotydyl transferase [Sulfolobus solfataricus]
Length = 407
Score = 336 bits (853), Expect = 3e-91
Identities = 179/405 (44%), Positives = 260/405 (64%), Gaps = 18/405 (4%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPFVDEFIIIVKYMKEKII 60
MKAVVLAAGKGERL P+T RPKP + V P+I + L ++++ II++ +
Sbjct: 1 MKAVVLAAGKGERLEPITHTRPKPFVPVLETPLILRHIRILKKYINKIIIVINSNHKDYF 60
Query: 61 ETLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIE-EEEFFAINGDIYFEQEAIRGLLHV 119
+T+ + ++ V Q E +GTA A+ +A+ Y+E +EEF I GD+ FE++A+ +++
Sbjct: 61 KTI------EGVSLVEQTEGKGTAAALRAAEKYLEGDEEFLVIYGDLLFEEDALDKIVNT 114
Query: 120 YKKTKANAALVVKKFDDLSQLGM-VKTEGGYVREIVEKPGNV-GGLANLGIYIFNPDVFE 177
A++ ++ +D + G+ VK + IVEKP N + N GIY F D+F
Sbjct: 115 -----EGEAILARESEDPRKFGVIVKDSENRLVRIVEKPENPPSNIINAGIYKFTYDIFS 169
Query: 178 FIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKTKLK 237
+I++ S RGE+E+TD +NL+ G KV Y+G W DIGRPWDL+E N+ +L +
Sbjct: 170 YIDKISLSSRGEFELTDAVNLI---GNKVKVVTYNGIWLDIGRPWDLIEANKVLLDKEKD 226
Query: 238 HDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDNCH 297
++ G +EE I V I +G +++SG+YI GPV IGKN IGPN +IRPY+ IG N
Sbjct: 227 RNL-GVIEENVKIKGKVVIEDGVIIKSGTYIEGPVYIGKNSVIGPNAYIRPYSVIGSNVK 285
Query: 298 IGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTITANLRHDNRTIKVEIKGKLE 357
+G EIK S+IM+N+ PHL+YVGDS++ E N GAGTITANLR D +KV IK +
Sbjct: 286 VGAFNEIKESVIMENAKIPHLSYVGDSVICEGVNFGAGTITANLRFDEEEVKVNIKNERV 345
Query: 358 DSGRRKLGAIIGHNVKTGINVTIYPGRKIGSGALVGPGVIVDKNI 402
SGR+KLGAI+G +V+TGINV+I PG KIG+ A + PG +VD+++
Sbjct: 346 SSGRKKLGAIVGAHVRTGINVSILPGVKIGAYAWIYPGAVVDRDV 390
>gb|AAG18651.1| (AE004970) glucose-1-phosphate thymidylyltransferase; GraD2
[Halobacterium sp. NRC-1]
Length = 401
Score = 308 bits (781), Expect = 7e-83
Identities = 164/402 (40%), Positives = 244/402 (59%), Gaps = 12/402 (2%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPFVDEFIIIVKYMKEKII 60
M+A+V+AAG+G R+ PLT+ RPKP++ VA ++E++L+ VDE++I+V Y ++I
Sbjct: 1 MQAIVVAAGRGTRMGPLTETRPKPLVPVAGATLLEHVLDAAAGVVDEYVIVVGYRGDQIR 60
Query: 61 ETLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLLHVY 120
E +G + G P+ Y Q +EGTA A+ A+ ++E +NGD+Y + L
Sbjct: 61 ERIGASYAGTPVVYAEQDTQEGTAHAVGCAEPHVEGP-CLVLNGDVYVTSALVEALAGA- 118
Query: 121 KKTKANAALVVKKFDDLSQLGMVKT-EGGYVREIVEKPGNVG-GLANLGIYIFNPDVFEF 178
A+ V D G+V+ + G V +VEKP + LANLG+Y F P VFE+
Sbjct: 119 ----DGTAMSVMPVADPQSYGVVERGDDGRVTNVVEKPTDPPTDLANLGLYRFTPRVFEY 174
Query: 179 IERTQESERGEYEITDTINLMIS--DGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKTKL 236
I+ + SERGEYE+TD + I DG A Y G W D+GRPW+LL N +L +
Sbjct: 175 IDTVERSERGEYELTDALARAIDREDGGVTAV-SYDGPWLDVGRPWELLAANSALLAEQ- 232
Query: 237 KHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDNC 296
+ +I GTV +GAT+ V + +G VR G+YI GPV I +GPN ++R T +G +
Sbjct: 233 EREINGTVADGATLTGRVVVEDGARVRDGAYIEGPVVIQSGADVGPNAYVRGATVVGPDV 292
Query: 297 HIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTITANLRHDNRTIKVEIKGKL 356
+GNAVE+KNSI+M ++ H YVGDS++G + N GAGT ANLRHD+ ++V++ G+L
Sbjct: 293 RVGNAVEVKNSILMADTAVGHHAYVGDSVLGADVNFGAGTKVANLRHDDAPVQVQVNGEL 352
Query: 357 EDSGRRKLGAIIGHNVKTGINVTIYPGRKIGSGALVGPGVIV 398
D+GRRK G ++G + KTGIN ++ G +G+G G +V
Sbjct: 353 VDTGRRKFGVVVGDDTKTGINTSLNAGVTLGTGTRTTLGAVV 394
>pir||F72591 probable sugar phosphate transferase APE1202 - Aeropyrum pernix
(strain K1) >gi|5104874|dbj|BAA80188.1| (AP000061) 360aa
long hypothetical sugar phosphate transferase [Aeropyrum
pernix]
Length = 360
Score = 210 bits (528), Expect = 3e-53
Identities = 125/338 (36%), Positives = 183/338 (53%), Gaps = 12/338 (3%)
Query: 72 ITYVSQVEEEGTAKAIYSAKDYIEEEEFFA-INGDIYFEQEAIRGLLHVYKKTKANAALV 130
+ +V Q GT A+ + + E F + GD+Y + GLL + A V
Sbjct: 20 VRFVEQGGALGTGHAVRRVLEELGGEGVFTFVYGDVYLDSR-FYGLLASAEAPSVLAGWV 78
Query: 131 VKKFDDLSQLGMVKTEGGYVREIVEKPGNV-GGLANLGIYIFNPDVFEFIERTQESERGE 189
+D G++ G VR +VEKP GG LG + + + + S RGE
Sbjct: 79 ----EDARWYGLLDVGDGLVRGVVEKPREPRGGWVFLGGFKVDGSFLGLLRGLEPSPRGE 134
Query: 190 YEITDTINLMISDGRKVAYFEYSGF-WSDIGRPWDLLEVNEYILKT-KLKHDIRGTVEEG 247
E+TD + + +G A G+ W D+GRPWD+L N + + G V
Sbjct: 135 VEVTDALEALAREGVLRALVGGEGWGWVDVGRPWDVLRANRMAFHDPQFSGGVEGEVHSS 194
Query: 248 ATIIPPVE---IGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDNCHIGNAVEI 304
A + VE I G + + S + GP IG R+GP +R YT + + ++G A E+
Sbjct: 195 AVLEGDVERIYIARGARIGAHSVVEGPAYIGPGARVGPGAHVRGYTVLLEGAYVGFASEV 254
Query: 305 KNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTITANLRHDNRTIKVEIKGKLEDSGRRKL 364
K S+IM+ + APHLNYVGDS+VGE+ NLGAGT+TANLR D R++++ +KG+ D+G RKL
Sbjct: 255 KASVIMEGARAPHLNYVGDSVVGEHVNLGAGTVTANLRFDGRSVRMTVKGERVDTGLRKL 314
Query: 365 GAIIGHNVKTGINVTIYPGRKIGSGALVGPGVIVDKNI 402
GA+IG +TGINV+I PG +IG ALV PG +V +++
Sbjct: 315 GAVIGGYAQTGINVSIMPGVRIGPRALVYPGCVVGRDV 352
>pir||A75098 glucose-1-phosphate thymidylyltransferase (grad-3) PAB0784 -
Pyrococcus abyssi (strain Orsay)
>gi|5458598|emb|CAB50086.1| (AJ248286)
glucose-1-phosphate thymidylyltransferase (graD-3)
[Pyrococcus abyssi]
Length = 352
Score = 190 bits (477), Expect = 3e-47
Identities = 120/339 (35%), Positives = 196/339 (57%), Gaps = 10/339 (2%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILEN-LDPFVDEFIIIVKYMKEKI 59
MKA++L+ G G RLRPLT + K ++ VANKP++ Y +E+ ++ + E IIV KE++
Sbjct: 1 MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIIVGPNKEQV 60
Query: 60 IETLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLLHV 119
IET+ I ++ Q E +G A AI A+DY+ ++F GD + +R H
Sbjct: 61 IETVKSVDWDANIEFIYQGEPKGLAHAILVARDYLGNDDFVMYLGDNILREGIVRHKEH- 119
Query: 120 YKKTKANAALVVKKFDDLSQLGMVKT--EGGYVREIVEKPGNV-GGLANLGIYIFNPDVF 176
++K+ +A++++ + + Q G+ + +G ++ ++EKP + LA +GIY F P +
Sbjct: 120 FEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLIEKPKHPPSNLALVGIYFFRPIIH 179
Query: 177 EFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKTKL 236
E + + S R E EITD I +I +G KV + + +G+W D G+P DLLE N +L ++
Sbjct: 180 EAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVL-DEI 238
Query: 237 KHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDNC 296
+ +I+ VE A II V+I EG + + I GP IG+N I N +I PYTS+G+N
Sbjct: 239 EREIK--VETRAKIIGRVKIEEGAKIDENTIIKGPAVIGRNAVI-RNAYIGPYTSVGNNV 295
Query: 297 HIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAG 335
I + E+++SIIMD S + +SI+G+ + G
Sbjct: 296 VIED-TEVEDSIIMDGSVIIGAGRIIESIIGKEVRIVRG 333
>gb|AAK41974.1| Sugar phosphate nucleotydyl transferase [Sulfolobus solfataricus]
Length = 344
Score = 189 bits (476), Expect = 4e-47
Identities = 122/340 (35%), Positives = 192/340 (55%), Gaps = 15/340 (4%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENL--DPFVDEFIIIVKYMKEK 58
M+AV+L G+G RLRPLT PK ++KVA KPI +++LE + D +I+ +
Sbjct: 1 MEAVILHGGQGTRLRPLTHTGPKQLIKVAGKPISQWVLEQIRDSGIKDILLILGDNTPTR 60
Query: 59 IIETLGD-EFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLL 117
+++ GD G ITYV Q + G A A+Y KD + E+ + ++ F L
Sbjct: 61 VVDYYGDGSKFGVNITYVYQGKARGLADAVYRVKDLVSEKFLVYLGDNLVFYD------L 114
Query: 118 HVYKKTKANAALVVKKFDDLSQLGMVKTEGGYVREIVEKPGN-VGGLANLGIYIFNPDVF 176
+ K +A++++ K D+ ++ G+ V +VEKP + LA +G+Y F ++F
Sbjct: 115 RKFLSFKGSASILLAKVDNPNRFGVAVINENKVIRLVEKPKEKISDLALVGVYGFTDEIF 174
Query: 177 EFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKTKL 236
E IE+ + S RGE EITD I +I++G++V Y G+W D G P D+LE N ++L
Sbjct: 175 EVIEKLKPSWRGELEITDAIQGLINEGKEVNYEIIQGWWKDTGTPKDILEANSFLLDRYA 234
Query: 237 KHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDNC 296
+ I G V E +TI V + +G VV++ S I GP IGK+ +I N +I P+TSIGD
Sbjct: 235 ERKIEGEV-ENSTIDGRVILEKGAVVKN-SVIRGPAYIGKDTKI-INSYIGPFTSIGDLS 291
Query: 297 HIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAGT 336
I + EI+ S+I+DN ++ + DS++G N+ + GT
Sbjct: 292 EISGS-EIEYSVILDNVRIKGVSLM-DSLIGNNSTVEKGT 329
>gi|11497938 glucose-1-phosphate thymidylyltransferase (graD-2) [Archaeoglobus
fulgidus] >gi|7448159|pir||E69290 glucose-1-phosphate
thymidylyltransferase (graD-2) homolog - Archaeoglobus
fulgidus >gi|2650311|gb|AAB90910.1| (AE001082)
glucose-1-phosphate thymidylyltransferase (graD-2)
[Archaeoglobus fulgidus]
Length = 352
Score = 186 bits (467), Expect = 5e-46
Identities = 118/336 (35%), Positives = 187/336 (55%), Gaps = 9/336 (2%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENL--DPFVDEFIIIVKYMKEK 58
MK V+L G G RLRPLT PK ++ VANKP+ +Y LE++ + II+ + E
Sbjct: 1 MKGVLLHGGAGTRLRPLTFTGPKQLIPVANKPVSQYCLEDMIGAGIKEVAIILGETYPEM 60
Query: 59 IIETLGDEFH-GKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLL 117
+ E GD G ITY+ Q + G A A+Y AKD++ +E+F GD Q+ I+ +
Sbjct: 61 VEEHYGDGSRFGCKITYIHQGKPLGIAHAVYLAKDFVGDEKFVVYLGDNLI-QDGIKEYV 119
Query: 118 HVYKKTKANAALVVKKFDDLSQLGMVKTEGGYVREIVEKPGNV-GGLANLGIYIFNPDVF 176
+ + +A +++K+ +D G+ K EG + ++EKP A +G+Y+F P VF
Sbjct: 120 KRFDEEDFDAFILLKEVEDPRAFGVAKFEGERLVGLIEKPKEPPSNYAVIGVYMFKPVVF 179
Query: 177 EFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKTKL 236
+ I+ + S RGE EITDT+ MI +G V Y + G+W D G+ D+L+VN IL +
Sbjct: 180 DIIKDLKPSWRGELEITDTLQKMIENGYNVGYAKLKGWWFDTGKAEDILKVNATILDERA 239
Query: 237 KHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDNC 296
K ++G V + I VE+GEG + + S + GP IG++C I N FI PYTS+G+
Sbjct: 240 KRSVKGEV-LASQIEGRVEVGEGAKI-TNSIVRGPAVIGEDCII-ENSFIGPYTSVGERT 296
Query: 297 HIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNL 332
I N+ ++ I++ S + + +S++G +
Sbjct: 297 VIKNS-SLEYCIVLSESIIEGVERIEESLIGRKVRI 331
>pir||F71151 probable glucose-1-phosphate thymidylyltransferase - Pyrococcus
horikoshii >gi|3256816|dbj|BAA29499.1| (AP000002) 356aa
long hypothetical glucose-1-phosphate
thymidylyltransferase [Pyrococcus horikoshii]
Length = 356
Score = 185 bits (464), Expect = 1e-45
Identities = 131/375 (34%), Positives = 209/375 (54%), Gaps = 32/375 (8%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILEN-LDPFVDEFIIIVKYMKEKI 59
MKA++L+ G G RLRPLT + K ++ VANKP++ Y +E+ ++ + E I+V + +
Sbjct: 5 MKALILSGGYGTRLRPLTYSQQKQLIPVANKPVLFYAIEDVIEAGIHEIGIVVGPNADLV 64
Query: 60 IETLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLLHV 119
+T+ I ++ Q E +G A AI A+DY+ +E+F GD + +R H
Sbjct: 65 KKTVMSVDWDANIEFIYQGEPKGLAHAILVARDYLGDEDFVMYLGDNILREGIVRHKEH- 123
Query: 120 YKKTKANAALVVKKFDDLSQLGMVKT--EGGYVREIVEKPGNV-GGLANLGIYIFNPDVF 176
++K+ +A++++ + + Q G+ + +G ++ +VEKP + LA +GIY F P +
Sbjct: 124 FEKSDYDASILLCEVPNPQQFGVAELSEDGKTIKRLVEKPKHPPSNLALVGIYFFRPIIH 183
Query: 177 EFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKTKL 236
E + + S R E EITD I +I +G KV + + +G+W D G+P DLLE N +L ++
Sbjct: 184 EAVRHIKPSWRNELEITDAIQWLIDNGYKVGWTKVTGWWKDTGKPEDLLEANRLVL-DEI 242
Query: 237 KHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDNC 296
+ +++ VE A II V+I EG + S I GP IGKN I N +I PYTS+G+N
Sbjct: 243 EKEVK--VETRAKIIGRVKIEEGAQIDENSVIKGPAVIGKNAVI-RNAYIGPYTSVGNNV 299
Query: 297 HIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTITANLRHDNRTIKVEIKGKL 356
I + E+++SI+MD DSI+ +GAG I ++ R +K+ IKG
Sbjct: 300 VIED-TEVEDSIVMD-----------DSII-----VGAGRIVESI--IGRGVKI-IKGNS 339
Query: 357 EDSGRRKLGAIIGHN 371
GRR IIG N
Sbjct: 340 HPMGRR---LIIGDN 351
>emb|CAB57473.1| (Y18930) glucose-1-phosphate thymidylyltransferase (graD-2)
[Sulfolobus solfataricus]
Length = 344
Score = 179 bits (450), Expect = 5e-44
Identities = 115/339 (33%), Positives = 192/339 (55%), Gaps = 15/339 (4%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENL-DPFVDEFIIIV-KYMKEK 58
M+AV+L G+G RLRPLT PK ++KVA KP+ +++LE + D + + II++ +
Sbjct: 1 MEAVILHGGQGTRLRPLTHTGPKQLIKVAGKPVSQWVLEQIRDAGIRDVIIVLGDNAPTR 60
Query: 59 IIETLGD-EFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLL 117
++E GD G ITYV Q + G A A+Y KD + ++ +Y + L
Sbjct: 61 VVEYYGDGSKFGVRITYVYQGKARGLADAVYKVKDVVSDKFL------VYLGDNLVPYDL 114
Query: 118 HVYKKTKANAALVVKKFDDLSQLGMVKTEGGYVREIVEKPGN-VGGLANLGIYIFNPDVF 176
+ K +A++++ K ++ ++ G+ + G V +++EKP + LA +G+Y F ++F
Sbjct: 115 SKFSSFKGSASILLAKVNNPNRFGVAVIKDGRVVKLIEKPKEQISDLALVGVYGFTREIF 174
Query: 177 EFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKTKL 236
+ IE + S RGE EITD I +I GR+V Y G+W D G P D+LE N ++L
Sbjct: 175 DVIESLKPSWRGELEITDAIQGLIDRGREVNYEIIQGWWKDTGTPKDILEANAFLLDRYA 234
Query: 237 KHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDNC 296
+ I G V + +T+ V I +G V+++ S + GP IG++ +I N +I P+TSIGD
Sbjct: 235 ESRIEGVV-DNSTVDGKVIIEKGAVIKN-SVVRGPTYIGRDTKI-INSYIGPFTSIGDQS 291
Query: 297 HIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAG 335
I ++ EI+ S+I+D + + DS++G N+ + G
Sbjct: 292 EITDS-EIEYSVILDGVKIRGVTLM-DSLIGNNSTVEKG 328
>gb|AAK41126.1| Sugar phosphate nucleotydyl transferase [Sulfolobus solfataricus]
Length = 344
Score = 179 bits (450), Expect = 5e-44
Identities = 115/339 (33%), Positives = 192/339 (55%), Gaps = 15/339 (4%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENL-DPFVDEFIIIV-KYMKEK 58
M+AV+L G+G RLRPLT PK ++KVA KP+ +++LE + D + + II++ +
Sbjct: 1 MEAVILHGGQGTRLRPLTHTGPKQLIKVAGKPVSQWVLEQIRDAGIRDVIIVLGDNAPTR 60
Query: 59 IIETLGD-EFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLL 117
++E GD G ITYV Q + G A A+Y KD + ++ +Y + L
Sbjct: 61 VVEYYGDGSKFGVRITYVYQGKARGLADAVYKVKDVVSDKFL------VYLGDNLVPYDL 114
Query: 118 HVYKKTKANAALVVKKFDDLSQLGMVKTEGGYVREIVEKPGN-VGGLANLGIYIFNPDVF 176
+ K +A++++ K ++ ++ G+ + G V +++EKP + LA +G+Y F ++F
Sbjct: 115 SKFSSFKGSASILLAKVNNPNRFGVAVIKDGRVVKLIEKPKEQISDLALVGVYGFTREIF 174
Query: 177 EFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKTKL 236
+ IE + S RGE EITD I +I GR+V Y G+W D G P D+LE N ++L
Sbjct: 175 DVIESLKPSWRGELEITDAIQGLIDRGREVNYEIIQGWWKDTGTPKDILEANAFLLDRYA 234
Query: 237 KHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDNC 296
+ I G V + +T+ V I +G V+++ S + GP IG++ +I N +I P+TSIGD
Sbjct: 235 ESRIEGVV-DNSTVDGKVIIEKGAVIKN-SVVRGPTYIGRDTKI-INSYIGPFTSIGDQS 291
Query: 297 HIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAG 335
I ++ EI+ S+I+D + + DS++G N+ + G
Sbjct: 292 EITDS-EIEYSVILDGVKIRGVTLM-DSLIGNNSTVEKG 328
>pir||G72325 glucose-1-phosphate thymidylyltransferase - Thermotoga maritima
(strain MSB8) >gi|4981396|gb|AAD35944.1|AE001752_11
(AE001752) glucose-1-phosphate thymidylyltransferase
[Thermotoga maritima]
Length = 355
Score = 176 bits (442), Expect = 4e-43
Identities = 114/337 (33%), Positives = 194/337 (56%), Gaps = 12/337 (3%)
Query: 2 KAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPF-VDEFIIIVKYMKEKII 60
KA+VL AGKG RLRPLT K ++ +ANKPI+ Y LEN+ ++E I+V +
Sbjct: 3 KAIVLCAGKGTRLRPLTFTTAKHLIPIANKPILFYSLENIARAGIEEVGIVVSPHNAEEF 62
Query: 61 ETL---GDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLL 117
+++ G+ F G I+Y+ Q E +G A A++ +++++ +E+F GD ++ + +
Sbjct: 63 KSIVGTGENF-GLRISYIIQEEPKGLAHAVWVSREFLGDEDFMMYLGDNLILED-LGKFV 120
Query: 118 HVYKKTKANAALVVKKFDDLSQLGMVKTEGGYVREIVEKPGNV-GGLANLGIYIFNPDVF 176
++ + A++++ D ++ G+ EG V ++VEKP LA +G+Y+F +F
Sbjct: 121 KDFENSDYAASILLSPVKDPTRFGVAVMEGDRVIKVVEKPKTPPSNLAIVGLYLFRNKIF 180
Query: 177 EFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKTKL 236
E I+ + S RGE EITD I +I G KV + G+W D G+P DLLE N IL +
Sbjct: 181 EGIKNIKPSWRGELEITDAIEYLIEKGEKVRGYIVYGWWKDTGKPEDLLEANRKIL-MET 239
Query: 237 KHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDNC 296
++ G +++ ++I PV IG+ + + S I GP IG+NC I N ++ PY+SIG+
Sbjct: 240 TEELLGEMDDKSSIQGPVRIGKASKI-VNSVIRGPAVIGENCFI-KNSYVGPYSSIGNRV 297
Query: 297 HIGNAVEIKNSIIMDNSNAPHL-NYVGDSIVGENTNL 332
+ + E++NSI+MD + + + SI+G+ ++
Sbjct: 298 ILEDC-EVENSIVMDECSITGVEKRIDSSILGKGVSV 333
>pir||S76366 hypothetical protein - Synechocystis sp. (strain PCC 6803)
>gi|1001590|dbj|BAA10218.1| (D64000) glucose-1-phosphate
thymidylyltransferase [Synechocystis sp.]
Length = 393
Score = 175 bits (440), Expect = 7e-43
Identities = 117/338 (34%), Positives = 188/338 (55%), Gaps = 10/338 (2%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDP--FVDEFIIIVKYMKEK 58
MKA++L+ GKG RLRPLT K ++ VANKPI+ Y +E + D III E+
Sbjct: 29 MKALILSGGKGTRLRPLTYTGAKQLVPVANKPILWYGIEAIAKAGITDIGIIISPETGEE 88
Query: 59 IIETLGD-EFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLL 117
I G+ E G ITY+ Q E G A A+ +A D++++ F GD + + L
Sbjct: 89 IKTITGNGEKFGIQITYILQSEPLGLAHAVKTAADFLQDSPFVMYLGDNLIQDHLEQFLA 148
Query: 118 HVYKKTKANAALVVKKFDDLSQLGMVKT-EGGYVREIVEKPGNV-GGLANLGIYIFNPDV 175
H K+ ++ +++++ + S G+ + G V +VEKP + LA +G+Y F P +
Sbjct: 149 HFQAKS-LDSLILLRRVSNPSAFGVATVNDQGKVLALVEKPEHPPSNLALVGLYFFAPTI 207
Query: 176 FEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKTK 235
+ I + S RGE EITD I +IS +V + G+W D G+ DLL N+ IL T
Sbjct: 208 HQAIANIEPSARGELEITDAIQYLISHDYRVESLQLKGWWLDTGKKDDLLAANQIILDTL 267
Query: 236 LKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDN 295
++ +I+GTV++ + I V IG + + S I GPV IG NC + NCFI PY+SI +
Sbjct: 268 VEKNIQGTVDDQSKISGRVTIGPHSQI-INSVIRGPVAIGPNCHL-ENCFIGPYSSIAEG 325
Query: 296 CHIGNAVEIKNSIIMDNSNAPHLNY-VGDSIVGENTNL 332
I +A ++++S+++ ++ + + DS++G+N +
Sbjct: 326 VKIRDA-DLEHSVVLQGASIVAIQQRIVDSVIGKNAKI 362
>gb|AAG18650.1| (AE004970) glucose-1-phosphate thymidylyltransferase; GraD5
[Halobacterium sp. NRC-1]
Length = 395
Score = 171 bits (429), Expect = 1e-41
Identities = 130/408 (31%), Positives = 200/408 (48%), Gaps = 40/408 (9%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENL-DPFVDEFIIIVKYMKEKI 59
M+AVVLAAGKGERL PLT++RPKP++ VAN+PI+E+I++ L V +++V +E++
Sbjct: 1 MQAVVLAAGKGERLWPLTENRPKPMVPVANQPILEHIVDALVSAGVTRVMLVVGSNRERV 60
Query: 60 IETLGDEFH-GKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLLH 118
D G I+YV Q + GT A+ A+ + E F A+NGD + + +
Sbjct: 61 QRHFEDGSRWGIEISYVVQDRQLGTGHALAQAESVVGES-FVALNGDRVIDASLVEDVWE 119
Query: 119 VYKKTKANAALVVKKFDDLSQLGMVKTEGGYVREIVEKPGN---VGGLANLGIYIFNPDV 175
++++ ++A+ V + + S G+V +GG V +I E+P N G+Y F P V
Sbjct: 120 CHRES-GDSAMGVTQVETPSAYGVVDLDGGTVTDIDEQPVPELVASEYINAGVYAFGPSV 178
Query: 176 FEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKTK 235
F I RT GE +TD ++ ++D ++ Y G W D+ PWDL+ N ++ T
Sbjct: 179 FAAIRRTDSY--GELALTDALDEQLAD-HELRAVRYDGRWLDVSEPWDLVAANSALI-TD 234
Query: 236 LKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIG----PNCFIRPYTS 291
+ D PPVE + G PV G C G P +R +
Sbjct: 235 RRFD------------PPVERRKPRGSVPGDDQQAPVGGGTVCGEGVIVHPQAVVRNGVA 282
Query: 292 IGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTITANLRHDNRTIKVE 351
+GDN +G I+ SI++ +S V DSIVG N +G T + D
Sbjct: 283 LGDNVTVGANAVIEQSILLPDSTVNPGAVVNDSIVGANATIGPNTTVEGGQTD------V 336
Query: 352 IKGKLEDSGRRKLGAIIGHNVKTGINVTIYPGRKIGSGALVGPGVIVD 399
+ G G R GA++G N + G VT+ PG ++VG +VD
Sbjct: 337 VLGDTVHQGVR-FGALVGDNAEVGAGVTVAPG------SIVGNSAVVD 377
>gb|AAD28517.1|AF126354_3 (AF126354) BlmD [Streptomyces bluensis]
Length = 355
Score = 170 bits (427), Expect = 2e-41
Identities = 111/336 (33%), Positives = 188/336 (55%), Gaps = 9/336 (2%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPF-VDEFIIIVKYMKEKI 59
MKA+VLA G G RLRP+T K ++ VANKP++ Y LE + + +IV M I
Sbjct: 1 MKALVLAGGSGTRLRPITHTSAKQLVPVANKPVLFYGLEAIAAAGIKNVGLIVGDMSGDI 60
Query: 60 IETLGD-EFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLLH 118
E +GD G I+Y+ Q E G A A+ ++DY+ E++F GD F I +
Sbjct: 61 SEAVGDGSKFGLSISYIEQREPLGLAHAVLISRDYLGEDDFAMYLGD-NFIVGGIDEPVR 119
Query: 119 VYKKTKANAALVVKKFDDLSQLGMVKTEG-GYVREIVEKPGNV-GGLANLGIYIFNPDVF 176
+++ + +A L++ D G+ + + G VR + EKP + LA +G+Y+F+P +
Sbjct: 120 EFRRDRPDAHLLLTHVSDPQSFGVAELDATGRVRGLEEKPRHPKSDLALVGVYLFSPAIH 179
Query: 177 EFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKTKL 236
E + + S RGE EITD + +I G+ V + +G+W D G D+LEVN +L+T
Sbjct: 180 EAVRAVKPSWRGELEITDAVQWLIDTGKDVRSRQITGYWKDTGNVSDMLEVNRLVLETID 239
Query: 237 KHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDNC 296
H G V+E + ++ V++ +G VVR+ S ++GP IG + + ++ P+TSIG++C
Sbjct: 240 PH-CAGHVDEHSDLVGRVQVDDGAVVRN-SRVVGPAVIGAG-SVVVDSYVGPFTSIGEDC 296
Query: 297 HIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNL 332
I ++ E++ SI++ ++ + V S++G + +
Sbjct: 297 VIEDS-EVEFSIVLRRASLSGVRRVEASLIGRHVQV 331
>emb|CAA07386.1| (AJ006985) StrD [Streptomyces glaucescens]
Length = 356
Score = 167 bits (418), Expect = 3e-40
Identities = 106/338 (31%), Positives = 183/338 (53%), Gaps = 8/338 (2%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPF-VDEFIIIVKYMKEKI 59
MKA+VLA G G RLRP+T K ++ VANKP++ Y LE + + + I+V +I
Sbjct: 1 MKALVLAGGAGPRLRPITHTSAKQLVPVANKPVLFYGLEAIAAAGITDVGIVVGDTVAEI 60
Query: 60 IETLGD-EFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLLH 118
E +GD G +TY+ Q + G + ++DY+ +++F GD F I +
Sbjct: 61 TEAVGDGSKFGLDVTYIPQRKPLGLGHGVRISRDYLGDDDFAMYLGD-NFVVGGIDQPIR 119
Query: 119 VYKKTKANAALVVKKFDDLSQLGMVKT-EGGYVREIVEKPGNVGG-LANLGIYIFNPDVF 176
++ + +A L++ + D G+ + E G VR + EKP + G LA +G+Y+F+P +
Sbjct: 120 AFRTHRPDAHLLLTRVSDPRSFGVAELDERGRVRHLEEKPTHPGSDLALVGVYLFSPAIH 179
Query: 177 EFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKTKL 236
E + + S RGE EIT + +I +G+ V SG+W D G D+LEVN +L+T +
Sbjct: 180 EAVRAIEPSWRGELEITHAVQWLIDEGKDVRSTLISGYWKDTGNVTDMLEVNRLVLET-V 238
Query: 237 KHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDNC 296
+ G V+E + +I V + EG V+R+ S +IGPV +G I + ++ P+TSI + C
Sbjct: 239 EPRCDGDVDEDSELIGRVRVDEGAVIRN-SRVIGPVVVGSGTTI-TDSYVGPFTSIAEGC 296
Query: 297 HIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGA 334
+ + + ++ N++ + + S++G + + A
Sbjct: 297 LVEDQPSWSSPFVLRNASISGVRRIEASLIGRHVRVTA 334
>pir||A75596 probable glucose-1-phosphate thymidylyltransferase - Deinococcus
radiodurans (strain R1)
>gi|6460571|gb|AAF12277.1|AE001862_103 (AE001862)
glucose-1-phosphate thymidylyltransferase, putative
[Deinococcus radiodurans]
Length = 361
Score = 165 bits (414), Expect = 8e-40
Identities = 109/314 (34%), Positives = 173/314 (54%), Gaps = 14/314 (4%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENL-DPFVDEFIIIVKYMKEKI 59
MKA++ AAG G RLRPLT RPKP+L+VA +PII + + L + + + I+V +
Sbjct: 10 MKALIPAAGLGTRLRPLTFTRPKPVLRVAGQPIIRHAIRTLTEAGITDIGIVVSDVTRDE 69
Query: 60 IETLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLLHV 119
I+ E +T ++Q ++ G A+ +A++++ +++F GD FE A R +
Sbjct: 70 IQHAVREIRDVKLTLINQHDQLGLGHAVLTAREWVGQDDFCVYLGDNLFEFGA-RPFIES 128
Query: 120 YKKTKANAALVVKKFDDLSQLGMVKTEGGYVREIVEKPGNV-GGLANLGIYIFNPDVFEF 178
+ + A + + K D + G+ + +G + +VEKP + LA G+Y F P +FE
Sbjct: 129 FHQKHPAALIALVKVADPTAFGVAELDGEQITRLVEKPKDPPSNLAVAGLYCFTPQIFEV 188
Query: 179 IERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYIL---KTK 235
++ S RGEYEITD I +I G+ V G+W D GRP DLL+ N +L +T
Sbjct: 189 LDVMPPSARGEYEITDGIQGLIERGQTVVGQRVEGWWKDTGRPADLLDANRLLLEQIETD 248
Query: 236 LKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDN 295
++ D+ G+ G I+P V+R S I+GPV IG++ I + +I P+TSIG
Sbjct: 249 VQGDMEGSRMTGRVIVP----ASSKVLR--SKIVGPVIIGEDVII-EDAYIGPFTSIGRG 301
Query: 296 CHIGNAVEIKNSII 309
I NA EI++S +
Sbjct: 302 TVIRNA-EIEHSSV 314
>pir||T48866 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) [validated]
- Streptomyces argillaceus >gi|1814004|emb|CAA71846.1|
(Y10907) TDP-D-Glucose synthase [Streptomyces
argillaceus] >gi|3334819|emb|CAA07754.1| (AJ007932)
dTDP-glucose synthase [Streptomyces argillaceus]
Length = 355
Score = 162 bits (407), Expect = 5e-39
Identities = 110/336 (32%), Positives = 180/336 (52%), Gaps = 9/336 (2%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENL-DPFVDEFIIIVKYMKEKI 59
MKA+VL+ G G RLRP+T PK ++ VANKP++ Y LE++ + + I+V +I
Sbjct: 1 MKALVLSGGSGTRLRPITHTSPKQLVPVANKPVLFYALEDIAQAGITDVGIVVGETAREI 60
Query: 60 IETLGD-EFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLLH 118
+ +GD G +TY+ Q + G A A+ A+DY+ +++F GD F I GL+
Sbjct: 61 EDAVGDGSKFGLQVTYLPQEKPLGLAHAVLIARDYLGDDDFVMYLGD-NFVVGGIAGLVD 119
Query: 119 VYKKTKANAALVVKKFDDLSQLGMVKTEG-GYVREIVEKPGNV-GGLANLGIYIFNPDVF 176
++ + +A +++ D + G+ + +G G V + EKP + +A +G+Y+F P V
Sbjct: 120 EFRADRPDARILLTPVPDPTAFGIAELDGEGRVVRLEEKPTHPKSDMAVIGVYLFTPLVH 179
Query: 177 EFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKTKL 236
E + + S RGE EIT I +I + V G+W D G D+LEVN +L+ +
Sbjct: 180 EAVRAIEPSWRGELEITHAIQWLIDNRHDVRSTVIHGYWKDTGNVMDMLEVNRTVLE-GV 238
Query: 237 KHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDNC 296
+ G V+ + +I V I G V S S I+GP IG I +I PYTS+ + C
Sbjct: 239 EPCTEGPVDAESEVIGRVRIEAGARV-SNSRIVGPAVIGSGTVIS-GSYIGPYTSVSEGC 296
Query: 297 HIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNL 332
I ++ EI+ SI++ +S + V S++G + +
Sbjct: 297 RIEDS-EIEFSIVLRDSRVRGVQRVRGSLIGRSVTV 331
>pir||T46521 probable dTDP-1-glucose synthase [imported] - Streptomyces
violaceoruber >gi|4218548|emb|CAA09637.1| (AJ011500)
putative dTDP-1-glucose synthase [Streptomyces
violaceoruber]
Length = 353
Score = 162 bits (407), Expect = 5e-39
Identities = 108/345 (31%), Positives = 182/345 (52%), Gaps = 21/345 (6%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPF-VDEFIIIVKYMKEKI 59
MKA++L+ G G RLRP T PK ++ VANKPI+ + LEN+ V+E ++V +++
Sbjct: 1 MKALILSGGMGTRLRPFTYSMPKQLVPVANKPILVHCLENVRAIGVEEVAVVVGDRADEV 60
Query: 60 IETLGD-EFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLLH 118
+GD G +TY+ Q G A + A++++ +E+F GD E I
Sbjct: 61 RAVVGDGSAFGLDVTYLQQEAPLGLAHCVSIAEEFLGDEDFVMYLGDNILA-EGIAESAR 119
Query: 119 VYKKTKANAALVVKKFDDLSQLGMVKTEG-GYVREIVEKPGNV-GGLANLGIYIFNPDVF 176
++ ++ A L++ K D G+ +T+ G V +VEKP LA +G+Y F V
Sbjct: 120 AFRDERSAARLLLTKVADPRAYGVAETDATGRVHALVEKPERPRSDLAVIGVYFFTAAVH 179
Query: 177 EFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKTKL 236
+ + + S RGE EITD I ++ G +V EY+G+W D G P DLL+ N +L +L
Sbjct: 180 DAVRAIEPSARGELEITDAIQYLVERGDRVVADEYTGYWKDTGSPDDLLDCNR-VLLGRL 238
Query: 237 KHDIRGTVEEGATIIPPVEIGEGTVV------RSGSYIIGPVKIGKNCRIGPNCFIRPYT 290
+ + G V+ +T+ EGTVV S S ++GP+ +G + + PYT
Sbjct: 239 RPGVHGEVDAASTV-------EGTVVVEAGRSWSDSRLVGPLVVGAG-SVVRGSELGPYT 290
Query: 291 SIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAG 335
++G +C + +A I++SI++D + + + S++G + + G
Sbjct: 291 ALGRDCVLEDA-GIRDSIVLDGVSIQGVRGLSGSLIGRSAAVRTG 334
>gb|AAD13545.1| (AF080235) NDP-hexose synthetase homolog [Streptomyces cyanogenus]
Length = 355
Score = 162 bits (406), Expect = 7e-39
Identities = 110/337 (32%), Positives = 174/337 (50%), Gaps = 9/337 (2%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENL-DPFVDEFIIIVKYMKEKI 59
MKA+VL+ G G RLRP + PK ++ +ANKP++E++L N+ D V E +IV E+I
Sbjct: 1 MKALVLSGGSGTRLRPFSHSMPKQLIPIANKPVLEHVLRNVRDLGVTEIGVIVGDRAEQI 60
Query: 60 IETLGD-EFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLLH 118
+GD G ITY+ Q G A + A+ ++ +++F GD E + +
Sbjct: 61 QAVIGDGSALGVEITYIPQEAPLGLAHCVELARPFLGDDDFVMYLGDNMLP-EGVERIAD 119
Query: 119 VYKKTKANAALVVKKFDDLSQLGMVKTEG-GYVREIVEKPGNV-GGLANLGIYIFNPDVF 176
+ + A +VV K D G+ + G V +VEKP LA +G+Y F P +
Sbjct: 120 EFTAGRPAAQVVVHKVPDPRAFGVAELAADGRVERLVEKPQEPKSDLALIGVYFFTPAIH 179
Query: 177 EFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKTKL 236
+ + + S RGE EITD I ++++G + EY G+W D GR D+LE N +L L
Sbjct: 180 KAVAAIEPSARGELEITDAIQWLVANGDRFKANEYKGYWKDTGRIEDVLECNRKLL-DDL 238
Query: 237 KHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDNC 296
K G V+ +T+I V + G S I GPV IG + + I P+TSIG +
Sbjct: 239 KPATEGEVDAASTLIGTVVVEAGP-KSSAPAIEGPVVIGAG-SVVKDSHIGPHTSIGRDV 296
Query: 297 HIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLG 333
+ I+ SI +D++ H+ + S++G + ++G
Sbjct: 297 RL-TGTSIEYSIALDDATISHVRDLHSSVIGRSASVG 332
>sp|P08075|STRD_STRGR GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (DTDP-GLUCOSE SYNTHASE)
(DTDP-GLUCOSE PYROPHOSPHORYLASE) (SUGAR-NUCLEOTIDYLATION
ENZYME) >gi|49261|emb|CAA68514.1| (Y00459) put.
sugaractivating enzyme [Streptomyces griseus]
Length = 355
Score = 162 bits (406), Expect = 7e-39
Identities = 106/352 (30%), Positives = 191/352 (54%), Gaps = 12/352 (3%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPF-VDEFIIIVKYMKEKI 59
MKA+VLA G G RLRP+T K ++ VANKP++ Y LE + + + I+V ++I
Sbjct: 1 MKALVLAGGTGTRLRPITHTSAKQLVPVANKPVLFYGLEAIRAAGIIDVGIVVGDTADEI 60
Query: 60 IETLGDEFH-GKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLLH 118
+ +GD G ++Y+ Q + G A + ++D++ E++F GD F + +
Sbjct: 61 VAAVGDGSRFGLKVSYIPQSKPLGLAHCVLISRDFLGEDDFIMYLGD-NFVVGVVEDSVR 119
Query: 119 VYKKTKANAALVVKKFDDLSQLGMVK-TEGGYVREIVEKPGNV-GGLANLGIYIFNPDVF 176
++ + +A L++ + + G+ + ++ G V + EKP + LA +G+Y+F+P +
Sbjct: 120 EFRAARPDAHLMLTRVPEPRSFGVAELSDSGQVLGLEEKPAHPKSDLALVGVYLFSPAIH 179
Query: 177 EFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKTKL 236
E + S RGE EITD + +I GR V SG+W D G D+LEVN +L+T
Sbjct: 180 EAVAAITPSWRGELEITDAVQWLIDAGRDVRSTVISGYWKDTGNVTDMLEVNRLVLET-T 238
Query: 237 KHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDNC 296
+ G V+E + +I V + EG VR+ S ++GP IG R+ N ++ P+TS+ ++C
Sbjct: 239 EPRCDGLVDERSDLIGRVLVEEGAEVRN-SRVMGPTVIGAGTRV-TNSYVGPFTSLAEDC 296
Query: 297 HIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTITANLRHDNRTI 348
+ ++ E++ SI++ ++ + + S++G + + T + H NR +
Sbjct: 297 VVEDS-EVEFSIVLRGASISGVRRIEASLIGRHVQV---TSAPEVPHANRLV 344
>pir||A26984 strD protein - Streptomyces griseus
Length = 355
Score = 160 bits (401), Expect = 3e-38
Identities = 105/352 (29%), Positives = 191/352 (53%), Gaps = 12/352 (3%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPF-VDEFIIIVKYMKEKI 59
MKA+VLA G G RLRP+T K ++ VANKP++ Y LE + + + I+V ++I
Sbjct: 1 MKALVLAGGTGTRLRPITHTSAKQLVPVANKPVLFYGLEAIRAAGIIDVGIVVGDTADEI 60
Query: 60 IETLGDEFH-GKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLLH 118
+ +GD G ++Y+ Q + G A + ++D++ E++F GD F + +
Sbjct: 61 VAAVGDGSRFGLKVSYIPQSKPLGLAHCVLISRDFLGEDDFIMYLGD-NFVVGVVEDSVR 119
Query: 119 VYKKTKANAALVVKKFDDLSQLGMVK-TEGGYVREIVEKPGNV-GGLANLGIYIFNPDVF 176
++ + +A L++ + + G+ + ++ G V + EKP + LA +G+Y+F+P +
Sbjct: 120 EFRAARPDAHLMLTRVPEPRSFGVAELSDSGQVLGLEEKPAHPKSDLALVGVYLFSPAIH 179
Query: 177 EFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKTKL 236
E + S RGE EITD + +I GR V SG+W D G D+LEVN +L+T
Sbjct: 180 EAVAAITPSWRGELEITDAVQWLIDAGRDVRSTVISGYWKDTGNVTDMLEVNRLVLET-T 238
Query: 237 KHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDNC 296
+ G V+E + +I V + EG VR+ S ++GP IG R+ N ++ P+TS+ ++C
Sbjct: 239 EPRCDGLVDERSDLIGRVLVEEGAEVRN-SRVMGPTVIGAGTRV-TNSYVGPFTSLAEDC 296
Query: 297 HIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTITANLRHDNRTI 348
+ ++ E++ SI++ ++ + + S++G + + T + H +R +
Sbjct: 297 VVEDS-EVEFSIVLRGASISGVRRIEASLIGRHVQV---TSAPEVPHAHRLV 344
>gb|AAF59934.1| (AF237895) dTDP-D-glucose synthase [Streptomyces antibioticus]
Length = 356
Score = 160 bits (401), Expect = 3e-38
Identities = 114/337 (33%), Positives = 177/337 (51%), Gaps = 10/337 (2%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPF-VDEFIIIVKYMKEKI 59
MKA+VLA G G RLRP+T K ++ VANKP++ Y LE + + + +IV ++
Sbjct: 1 MKALVLAGGSGTRLRPITHTSAKQLVAVANKPVLFYGLEAIAAAGITDVGLIVGDTAGEV 60
Query: 60 IETLGDEFH-GKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLLH 118
+GD G ITY+ Q G A A+ A Y+ +++F GD F I L+
Sbjct: 61 RAAVGDGAKFGLDITYIEQSRPLGLAHAVLIAHTYLGDDDFVMYLGD-NFIVGGIDDLVR 119
Query: 119 VYKKTKANAA-LVVKKFDDLSQLGMVKTEG-GYVREIVEKPGNV-GGLANLGIYIFNPDV 175
++ + AA +++ D S G+ + + G V + EKP + LA +G+Y F P +
Sbjct: 120 TFRDGRPPAARILLTHVSDPSAFGVAELDDDGRVVGLEEKPRHPKSDLALVGVYFFTPAI 179
Query: 176 FEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKTK 235
E + + S RGE EIT I +I +G + G+W D G D+LEVN +L+
Sbjct: 180 HEAVRAIEPSWRGELEITHAIQHLIDNGADIQSMVIEGYWKDTGNVADMLEVNRTVLE-D 238
Query: 236 LKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDN 295
L+ I GTV+E +I V +GEG V + S I+GP IG I + +I P+TS+GDN
Sbjct: 239 LEPRIEGTVDEHTVVIGRVVVGEGARV-TNSRIMGPAIIGAGAEIS-DSYIGPFTSVGDN 296
Query: 296 CHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNL 332
C I + E++ SI++ S + + S++G N +
Sbjct: 297 CRITGS-EMEFSIMLAESAITGVRRIEGSLIGRNVQV 332
>pir||T30872 dNDP-glucose synthase - Streptomyces viridochromogenes
>gi|1911169|emb|CAA72714.1| (Y11985) dNDP-glucose
synthase [Streptomyces viridochromogenes]
Length = 355
Score = 159 bits (399), Expect = 4e-38
Identities = 104/344 (30%), Positives = 189/344 (54%), Gaps = 11/344 (3%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENL-DPFVDEFIIIVKYMKEKI 59
MKA++L G G RLRP+T K ++ VAN+ ++ Y+L+++ + + E I+V +I
Sbjct: 1 MKALILVGGVGSRLRPITHTSAKQLVPVANRTVLSYVLDSIKEAGISEVGIVVGATAAEI 60
Query: 60 IETLGD--EFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLL 117
++GD EF G +TY+ Q G A A+ ++D++ +++F GD Y + I +
Sbjct: 61 QASVGDGAEF-GLDVTYIQQDAPRGLADAVLVSRDFLGDDDFVMYLGDNYVV-DGIVDFV 118
Query: 118 HVYKKTKANAALVVKKFDDLSQLGMVKT-EGGYVREIVEKPGNV-GGLANLGIYIFNPDV 175
+++ K A +++ + D + G+ + E G V +VEKP + LA +G+Y F+ V
Sbjct: 119 ADFRRDKPAAQVMLARVADPRRFGVAELDENGRVTAVVEKPQDPRSDLAIVGVYAFSSAV 178
Query: 176 FEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKTK 235
E + + S R E EITD + + G +V +W D+ D+LE+N ++L++
Sbjct: 179 HEAVAGIRPSWRNELEITDALQWLADHGHEVGSTVIDRYWKDVASVTDVLEMNRHLLES- 237
Query: 236 LKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDN 295
L+ I G V+E + ++ V + G + SGS I+GP IG + + + ++ P+TSI N
Sbjct: 238 LETRIDGEVDEASELVGRVVVEAGAKI-SGSRIVGPAVIGPD-TVVQDSYLGPFTSIEGN 295
Query: 296 CHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTITA 339
C + ++ EI+ SI++ ++ + V DS++G T + A T+
Sbjct: 296 CRVAHS-EIQYSIVLRGASIEGVARVEDSVIGRETEVNAAPRTS 338
>pir||T51105 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) [validated]
- Streptomyces antibioticus (ATCC 11891)
>gi|5902169|gb|AAD55453.1| (AF055579) dTDP-D-glucose
synthase [Streptomyces antibioticus]
Length = 356
Score = 159 bits (398), Expect = 6e-38
Identities = 114/337 (33%), Positives = 177/337 (51%), Gaps = 10/337 (2%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPF-VDEFIIIVKYMKEKI 59
MKA+VLA G G RLRP+T K ++ VANKP++ Y LE + + + +IV ++
Sbjct: 1 MKALVLAGGSGTRLRPITHTSAKQLVAVANKPVLFYGLEAIAAAGITDVGLIVGDTAGEV 60
Query: 60 IETLGDEFH-GKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLLH 118
+GD G ITY+ Q G A A+ A Y+ +++F GD F I L+
Sbjct: 61 PRAVGDGAKFGLDITYIEQSRPLGLAHAVLIAHTYLGDDDFVMYLGD-NFIVGGIDDLVR 119
Query: 119 VYKKTKANAA-LVVKKFDDLSQLGMVKTEG-GYVREIVEKPGNV-GGLANLGIYIFNPDV 175
++ + AA +++ D S G+ + + G V + EKP + LA +G+Y F P +
Sbjct: 120 TFRDGRRPAARILLTHVSDPSGFGVAELDDDGRVVGLEEKPRHPKSDLALVGVYFFTPAI 179
Query: 176 FEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKTK 235
E + + S RGE EIT I +I +G + G+W D G D+LEVN +L+
Sbjct: 180 HEAVRAIEPSWRGELEITHAIQHLIDNGADIQSMVIEGYWKDTGNVADMLEVNRTVLE-D 238
Query: 236 LKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDN 295
L+ I GTV+E +I V +GEG V + S I+GP IG I + +I P+TS+GDN
Sbjct: 239 LEPRIEGTVDEHTVVIGRVVVGEGARV-TNSRIMGPAIIGAGPEIS-DSYIGPFTSVGDN 296
Query: 296 CHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNL 332
C I + E++ SI++ S + + S++G N +
Sbjct: 297 CRITGS-EMEFSIMLAESAITGVRRIEGSLIGRNVQV 332
>pir||E72229 UDP-N-acetylglucosamine pyrophosphorylase - Thermotoga maritima
(strain MSB8) >gi|4982202|gb|AAD36696.1|AE001806_6
(AE001806) UDP-N-acetylglucosamine pyrophosphorylase
[Thermotoga maritima]
Length = 445
Score = 157 bits (393), Expect = 2e-37
Identities = 131/475 (27%), Positives = 216/475 (44%), Gaps = 97/475 (20%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPFVDEFIIIVKYMKEKII 60
M+A+VLAAGKG R++ PK + ++ +P+IE+++E + +++ + E +
Sbjct: 1 MRALVLAAGKGTRMKSKI---PKVLHPLSGRPMIEWVIETAGKVAQKVGVVLGFEAELVR 57
Query: 61 ETLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEE-EEFFAINGDI-YFEQEAIRGLLH 118
+ L + + Q E+ GTA A+ AKD+IE ++ + GD+ + ++ ++
Sbjct: 58 KALPEW-----VDVFVQGEQLGTAHAVMCAKDFIEPGDDVLILYGDVPLISENTLKRMIE 112
Query: 119 VYKKTKANAALVVKKFDDLSQLGMVKTEGGYVR--EIVEKPGNVGGLA--NLGIYIFNPD 174
++K A+ ++V +D S G V +G R E + P + + N G Y+F+ D
Sbjct: 113 EHRKG-ADVTILVADLEDPSGYGRVIQDGDKYRIIEDTDLPEELKSVTTINTGFYVFSGD 171
Query: 175 VF--EFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYIL 232
E E+ +GEY +TD +N KV + R DLLE+
Sbjct: 172 FLLRALPEIKNENAKGEYYLTDAVNF----AEKVR----------VVRTDDLLEITGVNT 217
Query: 233 KTKL--------KHDIRGTVEEGATIIPP--------VEIGEGTVVRSGSYIIGPVKIGK 276
+ L I +E G TI+ P VEIG TV+ ++I G ++G+
Sbjct: 218 RKTLVWLEEQLRMRKIEELLENGVTILDPATTYIHYSVEIGMDTVIYPMTFIEGKSRVGE 277
Query: 277 NCRIGP------------------NCF---------------IRPYTSIGDNCHIGNAVE 303
NC IGP CF +R T + + IGN VE
Sbjct: 278 NCEIGPMTRIVDCEIGNNVKITRSECFKSVIEDDVSVGPFARLREGTILKKSSKIGNFVE 337
Query: 304 IKNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTITANLRHDNRTIKVEIKGKLEDSGRRK 363
IK S I + + A HL+Y+GD+ VG+N N+GAGTIT N G++K
Sbjct: 338 IKKSTIGEGTKAQHLSYIGDAFVGKNVNVGAGTITCNY-----------------DGKKK 380
Query: 364 LGAIIGHNVKTGINVTIYPGRKIGSGALVGPGVIVDKNIPPNVLVVAKQEKIVKE 418
I G N ++ +IG GAL+G G ++ +++PP L + + ++VKE
Sbjct: 381 NPTFIEDGAFIGSNSSLVAPVRIGKGALIGAGSVITEDVPPYSLGLGRARQVVKE 435
>gb|AAG19459.1| (AE005038) glucose-1-phosphate thymidylyltransferase; GraD4
[Halobacterium sp. NRC-1]
Length = 240
Score = 156 bits (391), Expect = 4e-37
Identities = 90/236 (38%), Positives = 144/236 (60%), Gaps = 7/236 (2%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPF-VDEFIIIVKYMKEKI 59
M+AVVLAAG+G RLRPLT+D+PK ++++A KPI+ + E L ++ + IV Y K+ I
Sbjct: 1 MQAVVLAAGEGTRLRPLTEDKPKGMVEIAGKPILTHCFEQLVALGAEKIVAIVGYRKQNI 60
Query: 60 IETLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLLHV 119
I GDEF G PITY Q E+ G A A+ A++++ E+F + GD F + +++
Sbjct: 61 ISHYGDEFDGVPITYAHQREQNGLAHALLKAEEHV-NEDFMLMLGDNIFRAN-LEDVVNR 118
Query: 120 YKKTKANAALVVKK--FDDLSQLGMVKT-EGGYVREIVEKPGN-VGGLANLGIYIFNPDV 175
++ +A+AA +V++ +D+ S+ G+ T + G ++E+VEKP + L G Y F+P +
Sbjct: 119 QQEERADAAFLVEEVDWDEASRYGVCDTNDYGEIQEVVEKPDDPPSNLVMTGFYTFSPAI 178
Query: 176 FEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYI 231
F+ + Q S+R EYE++D I+L+I GR + G+ D+G P D E E I
Sbjct: 179 FQACKLVQPSDRAEYELSDAIDLLIKSGRTIDAIPMEGWRIDVGYPEDRDEAEERI 234
>pir||G75164 mannose-1-phosphate guanyltransferase PAB0317 - Pyrococcus abyssi
(strain Orsay) >gi|5457908|emb|CAB49398.1| (AJ248284)
MANNOSE-1-PHOSPHATE GUANYLTRANSFERASE [Pyrococcus
abyssi]
Length = 361
Score = 154 bits (386), Expect = 1e-36
Identities = 123/407 (30%), Positives = 200/407 (48%), Gaps = 60/407 (14%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENL-DPFVDEFIIIVKYMKEKI 59
M+AV+LA G G RL PLT RPKP++ NKP++EY++ NL + VDE I++V Y+KEKI
Sbjct: 1 MQAVLLAGGMGTRLLPLTIYRPKPMIPFFNKPLMEYMVNNLVEVGVDEIIVLVGYLKEKI 60
Query: 60 IETLGD--EFHGKPITYVS-QVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGL 116
IE GD EF G I Y + + + GTA A+ A+ +I E F + D+ + + L
Sbjct: 61 IEHFGDGKEF-GVEIKYSNGENVKFGTAGALKRAEKFI-EGTFIVASSDVLTNLD-FKSL 117
Query: 117 LHVYKKTKANAALVVKKFDDLSQLGM-VKTEGGYVREIVEKPGN---VGGLANLGIYIFN 172
L + K A + + K +D S G+ V + G + EKP L N GIY+F
Sbjct: 118 LEFHAKKGGIATMALTKVEDPSPYGVAVLDDEGKILYFKEKPRREEAPSNLVNAGIYVFE 177
Query: 173 PDVFEFIERTQESERGEYEITDTINL---MISDGRKVAYFEYSGFWSDIGRPWDLLEVNE 229
P++ + I + + + ++NL M+ +G + F + +W+D+GRP L+ E
Sbjct: 178 PEILDLIPKGKPFD-------FSLNLFPKMLEEGIPIYGFPFDEYWNDVGRPSTYLQATE 230
Query: 230 YILKTKLKHDIRGTVEEGATIIPPVEIG--EGTVVRSGSYIIGPVKIGKNCRIGPNCFIR 287
+ KLK +P + +G +G V R GS G I +N ++
Sbjct: 231 DVFLGKLK-------------LPQISVGRLKGNVERGGSLFTGSRCILRNPKVS------ 271
Query: 288 PYTSIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTITANLRHDNRT 347
+ +GDN IG V+I+ S+I N + ++I+GEN +G G
Sbjct: 272 GFAVLGDNVEIGRDVKIERSVIFSNVTIEDGAEIREAIIGENVYIGKG------------ 319
Query: 348 IKVEIKGKLEDSGRRKLGAIIGHNVKTGINVTIYPGRKIGSGALVGP 394
+ +E + D+ +II + + G NV I+ ++G +++ P
Sbjct: 320 VTIEPGSVIGDN------SIIEEHSRIGANVKIWADSRVGRESIILP 360
>pir||S58687 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) strD -
Streptomyces violaceoruber >gi|763512|gb|AAA99940.1|
(L37334) dTDP-glucose synthetase [Streptomyces
violaceoruber]
Length = 352
Score = 153 bits (384), Expect = 2e-36
Identities = 106/345 (30%), Positives = 180/345 (51%), Gaps = 22/345 (6%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPF-VDEFIIIVKYMKEKI 59
MKA++ G+RLRP T PK ++ VANKPI+ + LEN+ V+E ++V +++
Sbjct: 1 MKALICPED-GDRLRPFTYSMPKQLVPVANKPILVHCLENVRAIGVEEVAVVVGDRADEV 59
Query: 60 IETLGD-EFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLLH 118
+GD G +TY+ Q G A + A++++ +E+F GD E I
Sbjct: 60 RAVVGDGSAFGLDVTYLQQEAPLGLAHCVSIAEEFLGDEDFVMYLGDNILA-EGIAESAR 118
Query: 119 VYKKTKANAALVVKKFDDLSQLGMVKTEG-GYVREIVEKPGNV-GGLANLGIYIFNPDVF 176
++ ++ A L++ K D G+ +T+ G V +VEKP LA +G+Y F V
Sbjct: 119 AFRDERSAARLLLTKVADPRAYGVAETDATGRVHALVEKPERPRSDLAVIGVYFFTAAVH 178
Query: 177 EFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKTKL 236
+ + + S RGE EITD I ++ G +V EY+G+W D G P DLL+ N +L +L
Sbjct: 179 DAVRAIEPSARGELEITDAIQYLVERGDRVVADEYTGYWKDTGSPDDLLDCNR-VLLGRL 237
Query: 237 KHDIRGTVEEGATIIPPVEIGEGTVV------RSGSYIIGPVKIGKNCRIGPNCFIRPYT 290
+ + G V+ +T+ EGTVV S S ++GP+ +G + + PYT
Sbjct: 238 RPGVHGEVDAASTV-------EGTVVVEAGRSWSDSRLVGPLVVGAG-SVVRGSELGPYT 289
Query: 291 SIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAG 335
++G +C + +A I++SI++D + + + S++G + + G
Sbjct: 290 ALGRDCVLEDA-GIRDSIVLDGVSIQGVRGLSGSLIGRSAAVRTG 333
>emb|CAB88884.1| (AL353861) putative mannose-1-phosphate guanyltransferase
[Streptomyces coelicolor A3(2)]
Length = 831
Score = 153 bits (383), Expect = 3e-36
Identities = 108/404 (26%), Positives = 200/404 (48%), Gaps = 36/404 (8%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPF-VDEFIIIVKYMKEKI 59
MKAVV+A G+G RLRP+T PKP+L V N+PI+E++L L ++E ++ V+++ +
Sbjct: 1 MKAVVMAGGEGTRLRPMTSSMPKPLLPVVNRPIMEHVLRLLKRHGLNETVVTVQFLASLV 60
Query: 60 IETLGD-EFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLLH 118
GD E G +TY ++ + GTA ++ +A++ ++++ F I+GD + + + L++
Sbjct: 61 KNYFGDGEELGMELTYANEEKPLGTAGSVKNAEEALKDDAFLVISGDALTDFD-LTDLIN 119
Query: 119 VYKKTKANAALVVKKFDDLSQLGM-VKTEGGYVREIVEKP--GNV-GGLANLGIYIFNPD 174
+K+ + + + + + + G+ + E G V +EKP G V N GIY+ P+
Sbjct: 120 FHKEKGSLVTVCLTRVPNPLEFGITIVDEEGKVERFLEKPTWGQVFSDTVNTGIYVMEPE 179
Query: 175 VFEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKT 234
VF +++ + D ++ +G+ + + G+W D+G ++ +L+
Sbjct: 180 VFNYVDPDVPVDWS----GDVFPQLMKEGKPIYGYVAEGYWEDVGTHESYVKAQADVLER 235
Query: 235 KLKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGD 294
K+ DI +G I P V + EG V + + GP+ +G ++ IR +T IG
Sbjct: 236 KVDVDI-----DGFEISPGVWVAEGAEVHPDAVLRGPLYVGDYAKVEAGAEIREHTVIGS 290
Query: 295 NCHIGNAVEIKNSIIMDNSN-APHLNYVGDSIVGENTNLGAGTITANLRHDNRTIKVEIK 353
N + + + +++ DN PH N G +VG+NT++ R ++E
Sbjct: 291 NVVVKSGAFLHKAVVADNVYVGPHSNLRG-CVVGKNTDI------------MRAARIEDG 337
Query: 354 GKLEDSGRRKLGAIIGHNVKTGINVTIYPGRKIGSGALVGPGVI 397
+ D ++G NV +YP + I +GA V VI
Sbjct: 338 AVIGDE------CLVGEESIIQGNVRVYPFKTIEAGAFVNTSVI 375
>gb|AAF00210.1|AF164960_6 (AF164960) dNDP-glucose synthetase [Streptomyces fradiae]
Length = 355
Score = 152 bits (380), Expect = 7e-36
Identities = 113/354 (31%), Positives = 182/354 (50%), Gaps = 24/354 (6%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPF-VDEFIIIVKYMKEKI 59
MKA+VLA G G RLRP + PK ++ +AN P++ ++L NL V E +IV +I
Sbjct: 1 MKALVLAGGSGTRLRPFSYSMPKQLIPIANTPVLVHVLRNLRELGVTEAGVIVGNRGPEI 60
Query: 60 IETLGD--EFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAI--RG 115
LGD EF G +TY+ Q G A + +D++ +++F GD + RG
Sbjct: 61 SAVLGDGAEF-GMRVTYIPQDAPRGLAHTVAITRDFLCDDDFVMYLGDNMLPDGVVDMRG 119
Query: 116 LLHVYKKTKANAALVVKKFDDLSQLGMVKT-EGGYVREIVEKPGNV-GGLANLGIYIFNP 173
+H + A +VV K D G+ + G V +VEKP + +A +G+Y F
Sbjct: 120 GIH---RPSAGGQVVVYKVPDPRSFGVAELGPQGEVLRLVEKPRDPRSDMALVGVYFFTA 176
Query: 174 DVFEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILK 233
+ + + + S RGE EITD I ++S G V +Y G+W D G D+LE N ++L
Sbjct: 177 AIHDAVAAIEPSARGELEITDAIQWLVSSGADVRASQYDGYWKDTGNVEDVLECNRHLL- 235
Query: 234 TKLKHDIRGTVEEGATIIPPVEIGEGT-VVRS---GSYIIGPVKIGKNCRIGPNCFIRPY 289
L + GTV+ + + V I G VVRS G+ IIG + ++ +G P+
Sbjct: 236 DGLGARMDGTVDAASVLTGEVVIEPGAKVVRSRIMGAAIIGAGTVVQDSHVG------PH 289
Query: 290 TSIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTITANLRH 343
SIG C + ++ ++NSI +D ++ + + +S++G + ++G GT N R+
Sbjct: 290 ASIGRRCTVTDS-RVENSIALDEASVTGVRGLRNSLIGRSASVG-GTGQENERY 341
>pir||S66080 UDP-N-acetylglucosamine pyrophosphorylase gcaD - Bacillus subtilis
>gi|467439|dbj|BAA05285.1| (D26185) temperature
sensitive cell division [Bacillus subtilis]
>gi|2632317|emb|CAB11826.1| (Z99104)
UDP-N-acetylglucosamine pyrophosphorylase [Bacillus
subtilis]
Length = 456
Score = 150 bits (374), Expect = 4e-35
Identities = 133/470 (28%), Positives = 223/470 (47%), Gaps = 82/470 (17%)
Query: 3 AVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYIL-ENLDPFVDEFIIIVKYMKEKIIE 61
AVVLAAG+G R++ K + V KP++E+++ E L + + + IV + E++ +
Sbjct: 6 AVVLAAGQGTRMK---SKLYKVLHPVCGKPMVEHVVDEALKLSLSKLVTIVGHGAEEVKK 62
Query: 62 TLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEE--FFAINGDI-YFEQEAIRGLLH 118
LGD+ Y Q ++ GTA A+ A+ ++ +E+ I GD E + +L
Sbjct: 63 QLGDKSE-----YALQAKQLGTAHAVKQAQPFLADEKGVTIVICGDTPLLTAETMEQMLK 117
Query: 119 VYKKTKANAALVVKKFDDLSQLG-MVKTEGGYVREIVE-----KPGNVGGLANLGIYIF- 171
+ + +A A ++ +D + G ++++E G V++IVE + + N G Y F
Sbjct: 118 EHTQREAKATILTAVAEDPTGYGRIIRSENGAVQKIVEHKDASEEERLVTEINTGTYCFD 177
Query: 172 NPDVFEFIER-TQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIG-RPWDLLEVNE 229
N +F I++ + ++ +GEY + D I ++ ++G VA ++ F +G L E
Sbjct: 178 NEALFRAIDQVSNDNAQGEYYLPDVIEILKNEGETVAAYQTGNFQETLGVNDRVALSQAE 237
Query: 230 YILKTKLKHDIRGTVEEGATIIPPVE--------IGEGTVVRSGSYIIGPVKIGKNCRIG 281
+K ++ + ++ G T+I P+ IG TV+ G+ I G V+IG++ IG
Sbjct: 238 QFMKERIN---KRHMQNGVTLIDPMNTYISPDAVIGSDTVIYPGTVIKGEVQIGEDTIIG 294
Query: 282 PN---------------------------------CFIRPYTSIGDNCHIGNAVEIKNSI 308
P+ IRP + IG+ IGN VEIK +
Sbjct: 295 PHTEIMNSAIGSRTVIKQSVVNHSKVGNDVNIGPFAHIRPDSVIGNEVKIGNFVEIKKTQ 354
Query: 309 IMDNSNAPHLNYVGDSIVGENTNLGAGTITANLRHDNRTIKVEIKGKLEDSGRRKLGAII 368
D S A HL+YVGD+ VG + NLG G+IT N N+ + K+ED GA I
Sbjct: 355 FGDRSKASHLSYVGDAEVGTDVNLGCGSITVNYDGKNKYLT-----KIED------GAFI 403
Query: 369 GHNVKTGINVTIYPGRKIGSGALVGPGVIVDKNIPPNVLVVAKQEKIVKE 418
G N VT +G GA V G V +++P L +A+ ++ K+
Sbjct: 404 GCNSNLVAPVT------VGEGAYVAAGSTVTEDVPGKALAIARARQVNKD 447
>emb|CAC12604.1| (AL445067) mannose-1-phosphate guanyltransferase related protein
[Thermoplasma acidophilum]
Length = 359
Score = 148 bits (371), Expect = 8e-35
Identities = 106/348 (30%), Positives = 176/348 (50%), Gaps = 42/348 (12%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENL-DPFVDEFIIIVKYMKEKI 59
+K VV+A GKG RLRP+T PKP++ VA KP+I YIL+ + + II Y E +
Sbjct: 3 LKGVVMAGGKGTRLRPITYSIPKPLVPVAGKPVISYILDAFYRSGISDIIITTGYKFESL 62
Query: 60 IE-TLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLLH 118
I+ L ++ + I + + E GTA + A++++ ++ F +GDI + + I ++
Sbjct: 63 IKGVLENKNSQQNILFSVEKEAAGTAGGVKIAENFL-DDTFVVGSGDILIDFD-IGDMIK 120
Query: 119 VYKKTKANAALVVKKFDDLSQLGMVK-TEGGYVREIVEKPG---NVGGLANLGIYIFNPD 174
+++ K + V K DD SQ G+ + E GY++ +EKPG N G+YI +
Sbjct: 121 EHQRRKNKITIAVTKVDDPSQFGIAEIDEEGYIKRFLEKPGKNETFSDTINAGVYIMDRS 180
Query: 175 VFEFIERTQESERGEYEIT-DTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILK 233
+ +I T G+++ D ++S G K+ + G W D GRP D+++ N+ I+
Sbjct: 181 LLRYIPST-----GQFDFAKDLFPKLLSQGIKIGTYLIDGVWLDAGRPKDVIKANQ-IMV 234
Query: 234 TKLKHDIRGT--------VEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCF 285
K GT V +G +I PP+ IGEG V + S I G
Sbjct: 235 EKYGESFNGTGKAIIKSKVPQGCSIKPPIYIGEGVHVGNNSTISG--------------- 279
Query: 286 IRPYTSIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLG 333
+++ D IG+ V+I+NS+IM +S V +S++ +NT +G
Sbjct: 280 ----SAVYDGVSIGDDVQIENSVIMASSKIMRGTKVVNSVIMQNTTIG 323
>sp|P14192|GCAD_BACSU UDP-N-ACETYLGLUCOSAMINE PYROPHOSPHORYLASE
(N-ACETYLGLUCOSAMINE-1-PHOSPHATE URIDYLTRANSFERASE) (TMS
PROTEIN) >gi|80432|pir||S05371 tms protein - Bacillus
subtilis >gi|40217|emb|CAA34522.1| (X16518) tms gene
product (AA 1-456) [Bacillus subtilis]
Length = 456
Score = 146 bits (366), Expect = 3e-34
Identities = 132/470 (28%), Positives = 222/470 (47%), Gaps = 82/470 (17%)
Query: 3 AVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYIL-ENLDPFVDEFIIIVKYMKEKIIE 61
AVVLAAG+G R++ K + V KP++E+++ E L + + + IV + E++ +
Sbjct: 6 AVVLAAGQGTRMK---SKLYKVLHPVCGKPMVEHVVDEALKLSLSKLVTIVGHGAEEVKK 62
Query: 62 TLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEE--FFAINGDI-YFEQEAIRGLLH 118
LGD+ Y Q ++ GTA A+ A+ ++ +E+ I GD E + +L
Sbjct: 63 QLGDKSE-----YRVQAKQLGTAHAVKQAQPFLADEKGVTIVICGDTPLLTAETMEQMLK 117
Query: 119 VYKKTKANAALVVKKFDDLSQLG-MVKTEGGYVREIVE-----KPGNVGGLANLGIYIF- 171
+ + +A ++ +D + G ++++E G V++IVE + + N G Y F
Sbjct: 118 EHTQREAKRTILTAVAEDPTGYGRIIRSENGAVQKIVEHKDASEEERLVTEINTGTYCFD 177
Query: 172 NPDVFEFIER-TQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIG-RPWDLLEVNE 229
N +F I++ + ++ +GEY + D I ++ ++G VA ++ F +G L E
Sbjct: 178 NEALFRAIDQVSNDNAQGEYYLPDVIEILKNEGETVAAYQTGNFQETLGVNDRVALSQAE 237
Query: 230 YILKTKLKHDIRGTVEEGATIIPPVE--------IGEGTVVRSGSYIIGPVKIGKNCRIG 281
+K ++ + ++ G T+I P+ IG TV+ G+ I G V+IG++ IG
Sbjct: 238 QFMKERIN---KRHMQNGVTLIDPMNTYISPDAVIGSDTVIYPGTVIKGEVQIGEDTIIG 294
Query: 282 PN---------------------------------CFIRPYTSIGDNCHIGNAVEIKNSI 308
P+ IRP + IG+ IGN VEIK +
Sbjct: 295 PHTEIMNSAIGSRTVIKQSVVNHSKVGNDVNIGPFAHIRPDSVIGNEVKIGNFVEIKKTQ 354
Query: 309 IMDNSNAPHLNYVGDSIVGENTNLGAGTITANLRHDNRTIKVEIKGKLEDSGRRKLGAII 368
D S A HL+YVGD+ VG + NLG G+IT N N+ + K+ED GA I
Sbjct: 355 FGDRSKASHLSYVGDAEVGTDVNLGCGSITVNYDGKNKYLT-----KIED------GAFI 403
Query: 369 GHNVKTGINVTIYPGRKIGSGALVGPGVIVDKNIPPNVLVVAKQEKIVKE 418
G N VT +G GA V G V +++P L +A+ ++ K+
Sbjct: 404 GCNSNLVAPVT------VGEGAYVAAGSTVTEDVPGKALAIARARQVNKD 447
>pir||C71177 probable mannose-1-phosphate guanyltransferase - Pyrococcus
horikoshii >gi|3258127|dbj|BAA30810.1| (AP000007) 361aa
long hypothetical mannose-1-phosphate guanyltransferase
[Pyrococcus horikoshii]
Length = 361
Score = 146 bits (365), Expect = 4e-34
Identities = 114/404 (28%), Positives = 195/404 (48%), Gaps = 54/404 (13%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPF-VDEFIIIVKYMKEKI 59
M+AV+LA GKG RL PLT RPKP++ NKP++EY+L NL V+E I++V Y+KEKI
Sbjct: 1 MQAVLLAGGKGTRLLPLTVYRPKPMIPFFNKPLMEYMLMNLIGIGVEEIIVLVGYLKEKI 60
Query: 60 IETL--GDEFHGKPITYVS-QVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGL 116
IE GD+F G I Y + + + GTA A+ A+ +I ++ F + D+ +
Sbjct: 61 IEYFGRGDKF-GVEIKYSNGENIKLGTAGALKKAEKFI-DDTFIVASSDV-LTNLSFDSF 117
Query: 117 LHVYKKTKANAALVVKKFDDLSQLGMVKTEGG----YVREIVEKPGNVGGLANLGIYIFN 172
+ +++ A + + K +D + G+ + Y +E ++ L N GIYIF
Sbjct: 118 IRFHREKGGIATMALTKVEDPTPYGVAVLDNENRILYFKEKPKREEAPSNLVNAGIYIFE 177
Query: 173 PDVFEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYIL 232
P++ + I R + + D M+ +G + F + +W+D+GRP L+ E +
Sbjct: 178 PEILDLIPRGKAFDFS----LDLFPKMLEEGIPIYGFPFDEYWNDVGRPSTYLQATEDVF 233
Query: 233 KTKLKHDIRGTVEEGATIIPPVEIG--EGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYT 290
KL+ +P + +G +G + R GS G + +N + I +
Sbjct: 234 LGKLR-------------LPQINVGRDKGNIERGGSLFTGSKCLIRNPK------IVGFA 274
Query: 291 SIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTITANLRHDNRTIKV 350
+G+N +G V+I+ S+I N + ++I+GEN +G G + +
Sbjct: 275 VLGNNVKVGRDVKIERSVIFSNVTIEDEVEIREAIIGENVYIGRGAV------------I 322
Query: 351 EIKGKLEDSGRRKLGAIIGHNVKTGINVTIYPGRKIGSGALVGP 394
E + D+ ++I K G NV I+ K+G ++V P
Sbjct: 323 EPGSVIGDN------SVIEEYSKIGANVKIWTDSKVGRESIVLP 360
>pir||C70354 UDP-N-acetylglucosamine pyrophosphorylase - Aquifex aeolicus
>gi|2983227|gb|AAC06824.1| (AE000698)
UDP-N-acetylglucosamine pyrophosphorylase [Aquifex
aeolicus]
Length = 464
Score = 145 bits (361), Expect = 1e-33
Identities = 134/473 (28%), Positives = 213/473 (44%), Gaps = 84/473 (17%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENL-DPFVDEFIIIVKYMKEKI 59
M+AV+LAAG G R + ++PK + ++ KP++ Y++ N+ + +D+ ++V + +++
Sbjct: 1 MRAVILAAGLGTRFK---SEKPKVLHEILGKPMLWYVITNVRNGRIDDIAVVVGHKAQEV 57
Query: 60 IETLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFA--INGDI-YFEQEAIRG- 115
+E +E ++ + + GTA A+ +AKD+ E + INGD E IR
Sbjct: 58 MEAFKNE---NLKFFIQENPKGGTADAVLAAKDFFSSYEGYVLIINGDSPLVSGETIRNM 114
Query: 116 -----LLHVYKKTKANAALVVKKFDDLSQLGMVKTEGG---YVREIVEKPGNVGGLA--- 164
++ Y+ K ++ D + G + E G +R + EK A
Sbjct: 115 QQFIHMVRTYEGIKLGGVVLTTHLPDPTGYGRIIKEEGTDRIIRIVEEKDATPEEKAITE 174
Query: 165 -NLGIYIF-NPDVFEFIERTQESE-RGEYEITDTINLMISDGRKVAYFEYSGFWSDIG-- 219
N G YIF P + E + R + S GE +TD I M++ G +V F +G
Sbjct: 175 INAGTYIFYAPYLLEALYRIKPSPVTGELYLTDVIEYMVNKGYEVRSFMAKEPTEALGVN 234
Query: 220 RPWDLLEVNEYILKTKLKH--DIRGT---------VEEGATIIPPVE------------I 256
WDL V E ++K K+ RG +E +I P VE I
Sbjct: 235 TRWDLALV-ENVIKLKIARYWAERGVTVHYPETVWIEPDVSIEPDVEIFPDVMLKGKTKI 293
Query: 257 GEGTVVRSGSYI----------------IGPVKIGKNCRIGPNCFIRPYTSIGDNCHIGN 300
+G+V+ GS I I +I K +GP IR + IG+ IGN
Sbjct: 294 KKGSVIGKGSVIKDSLVEENVIVREYSVIENSEIKKRAVVGPFARIRNESVIGEEAEIGN 353
Query: 301 AVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTITANLRHDNRTIKVEIKGKLEDSG 360
VE+K S I A HL Y+GD+ VGENTN+GAGT+ AN G
Sbjct: 354 FVEVKKSSIGKGVKAKHLAYIGDATVGENTNIGAGTVFANY-----------------DG 396
Query: 361 RRKLGAIIGHNVKTGINVTIYPGRKIGSGALVGPGVIVDKNIPPNVLVVAKQE 413
+RK + +G + G N + ++G A + G +V+K+IP L V++ E
Sbjct: 397 KRKYESYVGKSAFIGSNSLLIAPIRVGDWAYIAGGSVVNKDIPEGALAVSRPE 449
>gb|AAK40653.1| Sugar phosphate nucleotydyl transferase [Sulfolobus solfataricus]
Length = 361
Score = 143 bits (356), Expect = 5e-33
Identities = 100/339 (29%), Positives = 165/339 (48%), Gaps = 32/339 (9%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENL-DPFVDEFIIIVKYMKEKI 59
+ A+VLA G RLRPL+ +PK + + NKPI+ YILE+L + V + + ++ M +KI
Sbjct: 2 VSAIVLAGGYATRLRPLSLTKPKALFPILNKPILGYILESLINSDVSDIYLSLRVMADKI 61
Query: 60 IETLGDEFHGKPITYVSQVEEEGTAKAI-YSAKDYIEEEEFFAINGDIYFEQEAIRGLLH 118
I+ L D + + E G A + ++ Y +++ I GDIY E I+ LL
Sbjct: 62 IDYLKDTSMLDKVKIEVESEPLGDAGPLKLISQKYNLDDDVLVIYGDIYSEIN-IKSLLD 120
Query: 119 VYKKTKANAALVVKKFDDLSQLGMVKTEGGYVREIVEKPGN-VGGLANLGIYIFNPDVFE 177
Y K +A +V + +D + G++ TE + E++EKP + L N G+YIF D+F+
Sbjct: 121 FYYKKSCDAVVVGTEVEDPRRYGVLYTENDVLVELIEKPKKPISNLINGGVYIFKKDLFK 180
Query: 178 FIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKTKLK 237
+E + D + ++ + ++ ++Y G W+DIG P D L +N +L K
Sbjct: 181 LVETPSSISK------DFLPKLLRT-KSISVYKYHGIWADIGVPDDYLRLNFEVLVQKYP 233
Query: 238 H---DIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGD 294
+ V E +T+IPP IG V IG + +I T +G+
Sbjct: 234 KGYINSSAKVSEKSTLIPPYYIGSKNV------------------IGEDAYITSNTILGN 275
Query: 295 NCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLG 333
+ IG I SI+M+ Y+ SI+ + T +G
Sbjct: 276 DVEIGKGTYISESILMNKVQVKEYTYISGSIIADKTKIG 314
>pir||A72589 probable glucose-1-phosphate thymidylyltransferase APE1181 -
Aeropyrum pernix (strain K1) >gi|5104853|dbj|BAA80167.1|
(AP000061) 355aa long hypothetical glucose-1-phosphate
thymidylyltransferase [Aeropyrum pernix]
Length = 355
Score = 140 bits (349), Expect = 3e-32
Identities = 112/340 (32%), Positives = 174/340 (50%), Gaps = 26/340 (7%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPF-VDEFIIIVKYMKEKI 59
+K ++LAAG+G RLRP T RPK ++ + KPII+Y +++L V + ++V Y +KI
Sbjct: 2 VKGLILAAGEGSRLRPFTFSRPKHLIPLLGKPIIQYAIDDLVSINVRDIGVVVGYFGDKI 61
Query: 60 IETLG-DEFHGKPITYVSQVEEEGTAKAIYSA-KDYIEEEEFFAINGDIYFEQEAIRGLL 117
E LG D G TY+ Q + G A AIY A K ++EF GD R
Sbjct: 62 KEFLGEDSRFGAKFTYIVQKKRLGIAHAIYRAIKQGFIDKEFIVYLGDNILSGGISR--- 118
Query: 118 HV--YKKTKANAALVVKKFDDLSQLGMVKTEGGYVREIVEKP-GNVGGLANLGIYIF-NP 173
HV + + + +++ K D + G+ G + ++VEKP ++ LA +G+Y+F +P
Sbjct: 119 HVKSWGEAGSEVHILLTKVRDPGRFGIAVLRDGKILKLVEKPQEHISDLAVVGVYMFRDP 178
Query: 174 D-VFEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYIL 232
+ V + + S RGEYEITD I + G KV + +G+W D+G LL+ Y+L
Sbjct: 179 ELVAKAFSTLKPSWRGEYEITDLIQWFVDKGYKVTFSLVTGWWKDVGTYEGLLDA-IYLL 237
Query: 233 KTKLKHDIRGTVE---EGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPY 289
+K + G +E G ++ I EGTV GP IGK+ IG + + Y
Sbjct: 238 LDNVKPRVEGKIEGEVRGRVVVEEGAIVEGTV-------HGPAYIGKDVYIGRSGLVEHY 290
Query: 290 TSIGDNCHIGNAVEIKNSIIMDNSNAPHLN--YVGDSIVG 327
S+ I + + S+I+D S +LN + DS+VG
Sbjct: 291 VSMEQGSRIISGT-VARSMILDESEL-YLNKARLVDSVVG 328
>gb|AAF60300.1|AF234177_1 (AF234177) GDP-mannose pyrophosphorylase [Pichia angusta]
Length = 364
Score = 140 bits (349), Expect = 3e-32
Identities = 107/346 (30%), Positives = 167/346 (47%), Gaps = 40/346 (11%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENL-DPFVDEFIIIVKYMKEKI 59
MK ++L G G RLRPLT PKP+++ N+P+I + +E L + + ++ V Y E +
Sbjct: 1 MKGLILVGGYGTRLRPLTLSLPKPLVEFGNRPMILHQIEALANAGCTDIVLAVNYKPEVM 60
Query: 60 IETLG--DEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEE--FFAINGDIYFEQEAIRG 115
+ L ++ +G IT+ + E GTA + A+ ++++ F +N D+ E +R
Sbjct: 61 VGALKQYEKEYGVSITFSVEEEPLGTAGPLKLAEKILKKDNTPIFVLNSDVICEYP-LRD 119
Query: 116 LLHVYKKTKANAALVVKKFDDLSQLGMV---KTEGGYVREIVEKPGN-VGGLANLGIYIF 171
LL + A +V K D+ S+ G++ + + VEKP VG N GIY+
Sbjct: 120 LLEFHTAHGGEATIVATKVDEPSKYGVIVHDRDVPNLIERFVEKPVEFVGNRINAGIYVL 179
Query: 172 NPDVFEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYI 231
NP V + IE S E T +++ +K+ F+ G+W D+G+P D L
Sbjct: 180 NPSVIDLIEMRPTSIEHE-----TFPILVEQ-KKLYSFDLPGYWMDVGQPKDFLSGMCLY 233
Query: 232 LKTKLKHD---IRGTVEEGATIIPPVEIGEGTVVRSGSYIIGP-VKIGKNCRIGPNCFIR 287
L K + + T EE V G+ +I P KIGK C+IGPN I
Sbjct: 234 LSALTKKNSNLLTSTSEE--------------YVNGGNVLIDPSAKIGKGCKIGPNVVIG 279
Query: 288 PYTSIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLG 333
P NC IG+ V I+ S I+ NS +V +IVG N+ +G
Sbjct: 280 P------NCIIGDGVRIQRSTILKNSQIKDHAWVKSTIVGWNSTVG 319
>gb|AAB50923.1| (L47163) glucose-1-phosphate thymidylyltransferase [Streptomyces
peucetius] >gi|1588468|prf||2208414A glucose phosphate
thymidylate transferase [Streptomyces peucetius]
Length = 351
Score = 138 bits (345), Expect = 9e-32
Identities = 92/281 (32%), Positives = 145/281 (50%), Gaps = 8/281 (2%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENL-DPFVDEFIIIVKYMKEKI 59
MKA+VL+ G G RLRP T PK ++ VANKP++ Y+LE++ + E I+V +I
Sbjct: 1 MKALVLSGGSGTRLRPFTHTSPKQLVPVANKPVLYYVLEDIAQASITEVGIVVGETSNEI 60
Query: 60 IETLG--DEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLL 117
+ +G D F G +TY+ Q G A A+ A+DY+ EE+F GD F I G
Sbjct: 61 RKAVGSGDRF-GLRVTYLPQEAPLGLAHAVLIARDYLGEEDFVMYLGD-NFVVGGIAGNS 118
Query: 118 HVYKKTKANAALVVKKFDDLSQLGMVKTE-GGYVREIVEKPGNV-GGLANLGIYIFNPDV 175
++ + +A +++ + D S G+ + G V + EKP + LA +GIY+F P V
Sbjct: 119 STFRAERPDAQILLTRVSDPSSFGVAEIGCDGRVVALEEKPRHPRSDLAVVGIYLFTPVV 178
Query: 176 FEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKTK 235
E + S RGE EITD + ++ V Y SG+W D G D+LEVN +L
Sbjct: 179 HEAVRALTPSRRGELEITDALQWLLDGPYDVRYTTISGYWKDTGNVADMLEVNRAVL-DG 237
Query: 236 LKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGK 276
++ + G + + ++ V I G +R+ + + G+
Sbjct: 238 IEPGMEGQADAASELVGRVRIEAGAQIRASRIVARRHRAGR 278
>pir||G69101 mannose-1-phosphate guanyltransferase - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2622888|gb|AAB86225.1| (AE000931)
mannose-1-phosphate guanyltransferase [Methanobacterium
thermoautotrophicum]
Length = 385
Score = 138 bits (345), Expect = 9e-32
Identities = 94/338 (27%), Positives = 165/338 (48%), Gaps = 13/338 (3%)
Query: 4 VVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILEN-LDPFVDEFIIIVKYMKEKIIET 62
VV+A GKG R+RPLT RPKP++ VAN+PI++YI+ LD + ++ + Y+K++I
Sbjct: 7 VVMAGGKGTRIRPLTFSRPKPLVPVANRPILDYIIHRVLDSGYSKVVMTLGYLKDQIRSH 66
Query: 63 LGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLLHVYKK 122
+ E+ + + + GTA + +A I E F ++GD+ F+ + +R ++ ++K
Sbjct: 67 VLAEYPEIDFRFSVEKKPLGTAGGVKAAASEI-NETFIVLSGDVIFDLD-LREMVKFHRK 124
Query: 123 TKANAALVVKKFDDLSQLGM-VKTEGGYVREIVEKPGN---VGGLANLGIYIFNPDVFEF 178
A + + +D S G+ V + G ++ EKP +AN GIY+ P+V E
Sbjct: 125 KNALVTVALTPVEDPSHYGIAVLDDDGKIKRFHEKPRPEEVFSKIANAGIYVMEPEVIEH 184
Query: 179 IERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKTKLKH 238
I + D ++I + F + G+W+D G+P L N +L +
Sbjct: 185 IPQGSSDFS-----ADIFPVLIERDAGMYGFLFDGYWNDAGKPNTFLRANHDVLNGTVTP 239
Query: 239 DIRGTV-EEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDNCH 297
+ G + EE + IG V+ I+GP +G R+ +I T IG +
Sbjct: 240 EPDGEIAEEVPGRFGKIWIGRDVVIGDRVRIVGPAVLGDGSRVDDGAYIGKNTVIGSRVN 299
Query: 298 IGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAG 335
+G I+ S+I+D + + + +V E+ +GAG
Sbjct: 300 VGENSFIRGSVILDGCVIGRGSQLLNCVVDEDCEIGAG 337
>pir||T41209 mannose-1-phosphate guanyltransferase - fission yeast
(Schizosaccharomyces pombe) >gi|3581924|emb|CAA20770.1|
(AL031538) mannose-1-phosphate guanyltransferase
[Schizosaccharomyces pombe]
Length = 363
Score = 138 bits (345), Expect = 9e-32
Identities = 110/351 (31%), Positives = 169/351 (47%), Gaps = 36/351 (10%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPF-VDEFIIIVKYMKEKI 59
MKA++L G G RLRPLT PKP+++ NKP+I + +E L V + ++ V Y E +
Sbjct: 1 MKALILVGGFGTRLRPLTLTLPKPLVEFGNKPMILHQVEALAAAGVTDIVLAVNYRPEIM 60
Query: 60 IETLG--DEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEE--FFAINGDIYFEQEAIRG 115
+E L ++ + IT+ + E GTA + A+D + ++ FF +N D+ E
Sbjct: 61 VEALKKYEKEYNVNITFSVENEPLGTAGPLALARDILAKDHSPFFVLNSDVICEYP-FAD 119
Query: 116 LLHVYKKTKANAALVVKKFDDLSQLGMV---KTEGGYVREIVEKPGN-VGGLANLGIYIF 171
L +K A +VV K ++ S+ G+V + VEKP V N GIYI
Sbjct: 120 LAAFHKAHGAEGTIVVTKVEEPSKYGVVVHYPNSESLIERFVEKPVEFVSNRINGGIYIL 179
Query: 172 NPDVFEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYI 231
NP V + IE S E M++D +++ F+ G+W D+G+P D L
Sbjct: 180 NPSVLDRIEPRPTSIEKE-----VFPAMVND-KQLHSFDLEGYWMDVGQPKDYLTGTCLY 233
Query: 232 LKTKLKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGP-VKIGKNCRIGPNCFIRPYT 290
L + KH + II G+ +I P IGKNC+IGPN I P
Sbjct: 234 LSSLRKHKPEILAPASSNII-------------GNVLIDPSATIGKNCKIGPNVVIGPNV 280
Query: 291 SIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTITANL 341
+IGD + +K+S + D++ +V SIVG N+ LG+ + N+
Sbjct: 281 TIGDGVRLQRCAILKSSRVRDHA------WVKSSIVGWNSTLGSWSRLENV 325
>emb|CAB58292.1| (AL121851) mannose-1-phosphate guanyltransferase [Leishmania major]
Length = 379
Score = 138 bits (344), Expect = 1e-31
Identities = 114/343 (33%), Positives = 171/343 (49%), Gaps = 25/343 (7%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPF-VDEFIIIVKYMKEKI 59
M+AV+L G G RLRPLT PKP++ NKP+I + +E L V E I+ V Y E +
Sbjct: 9 MRAVILVGGFGTRLRPLTLTTPKPLVPFCNKPMIIHQIEALKAVGVTEVILAVAYRPEAM 68
Query: 60 IETLGDEFHGKPITYVSQVEEE--GTAKAIYSAKDYIEEEE--FFAINGDIYFEQEAIRG 115
E + + + +V VEEE GTA + A+D + +++ FF +N D+ ++
Sbjct: 69 KEQMDEWSRKLGVLFVFSVEEEPLGTAGPLALARDILMQDDKPFFVLNSDVTCPFP-MQE 127
Query: 116 LLHVYKKTKANAALVVKKFDDLSQLGMV--KTEGGYVREIVEKPGN-VGGLANLGIYIFN 172
LL +K ++V + + G+V + + VEKP + +G N GIYIFN
Sbjct: 128 LLDFHKAHGGEGTIMVSQVTQWEKYGVVVYSPQNYQIERFVEKPSSFLGDRINAGIYIFN 187
Query: 173 PDVFEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWD-LLEVNEYI 231
+ + I + S E EI + M ++G+ A F GFW DIG+P D +L + +YI
Sbjct: 188 KSILDRIPPCRTSI--EKEIFPS---MAAEGQLYA-FNLEGFWMDIGQPKDYILGMTKYI 241
Query: 232 LKTKLKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTS 291
L H R T + G TV+ G+ +I P + +IG I PY S
Sbjct: 242 --PFLVHSNRETEKLHTEATKHQRGGRFTVI--GASLIDP-----SAKIGDGAVIGPYAS 292
Query: 292 IGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGA 334
IG NC IG + I N+ I++NS + V SIVG N +G+
Sbjct: 293 IGANCVIGESCRIDNAAILENSKVGKGSMVSRSIVGWNNRIGS 335
>gi|6320148 mannose-1-phosphate guanyltransferase, GDP-mannose
pyrophosphorylase; Psa1p [Saccharomyces cerevisiae]
>gi|1709086|sp|P41940|MPG1_YEAST MANNOSE-1-PHOSPHATE
GUANYLTRANSFERASE (ATP-MANNOSE-1-PHOSPHATE
GUANYLYLTRANSFERASE) (NDP-HEXOSE PYROPHOSPHORYLASE)
>gi|2132332|pir||S67590 mannose-1-phosphate
guanylyltransferase (EC 2.7.7.13) - yeast (Saccharomyces
cerevisiae) >gi|1292898|gb|AAC49289.1| (U19608) Psa1p
[Saccharomyces cerevisiae] >gi|1431053|emb|CAA98617.1|
(Z74103) ORF YDL055c [Saccharomyces cerevisiae]
Length = 361
Score = 137 bits (342), Expect = 2e-31
Identities = 100/342 (29%), Positives = 166/342 (48%), Gaps = 35/342 (10%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENL-DPFVDEFIIIVKYMKEKI 59
MK ++L G G RLRPLT PKP+++ N+P+I + +E L + V + ++ V Y E +
Sbjct: 1 MKGLILVGGYGTRLRPLTLTVPKPLVEFGNRPMILHQIEALANAGVTDIVLAVNYRPEVM 60
Query: 60 IETLG--DEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEE--FFAINGDIYFEQEAIRG 115
+ETL ++ +G IT+ + E GTA + A+D ++++ FF +N D+ E +
Sbjct: 61 VETLKKYEKEYGVNITFSVETEPLGTAGPLKLAEDVLKKDNSPFFVLNSDVICEYP-FKE 119
Query: 116 LLHVYKKTKANAALVVKKFDDLSQLGMVKTE---GGYVREIVEKPGN-VGGLANLGIYIF 171
L +K +V K D+ S+ G++ + + VEKP VG N G+YI
Sbjct: 120 LADFHKAHGGKGTIVATKVDEPSKYGVIVHDIATPNLIDRFVEKPKEFVGNRINAGLYIL 179
Query: 172 NPDVFEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYI 231
NP+V + IE S E T +++ + +++ F+ GFW D+G+P D L
Sbjct: 180 NPEVIDLIEMKPTSIEKE-----TFPILVEE-KQLYSFDLEGFWMDVGQPKDFLSGTVLY 233
Query: 232 LKTKLKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTS 291
L + K P ++ G + + I KI +IGP+ I P +
Sbjct: 234 LNSLAKRQ-------------PKKLATGANIVGNALIDPTAKISSTAKIGPDVVIGPNVT 280
Query: 292 IGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLG 333
IGD V I S+++ NS + + V +IVG N+ +G
Sbjct: 281 IGD------GVRITRSVVLCNSTIKNHSLVKSTIVGWNSTVG 316
>gb|AAA69677.1| (U24437) mannose-1-phosphate guanyltransferase [Saccharomyces
cerevisiae]
Length = 361
Score = 136 bits (338), Expect = 6e-31
Identities = 100/342 (29%), Positives = 165/342 (48%), Gaps = 35/342 (10%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENL-DPFVDEFIIIVKYMKEKI 59
MK ++L G G RLRPLT PKP+++ N+P+I + +E L + V + + V Y E +
Sbjct: 1 MKGLILVGGYGTRLRPLTLTVPKPLVEFGNRPMILHQIEALANAGVTDIALAVNYRPEVM 60
Query: 60 IETLG--DEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEE--FFAINGDIYFEQEAIRG 115
+ETL ++ +G IT+ + E GTA + A+D ++++ FF +N D+ E +
Sbjct: 61 VETLKKYEKEYGVNITFSVETEPLGTAGPLKLAEDVLKKDNSPFFVLNSDVICEYP-FKE 119
Query: 116 LLHVYKKTKANAALVVKKFDDLSQLGMVKTE---GGYVREIVEKPGN-VGGLANLGIYIF 171
L +K +V K D+ S+ G++ + + VEKP VG N G+YI
Sbjct: 120 LADFHKAHGGKGTIVATKVDEPSKYGVIVHDIATPNLIDRFVEKPKEFVGNRINAGLYIL 179
Query: 172 NPDVFEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYI 231
NP+V + IE S E T +++ + +++ F+ GFW D+G+P D L
Sbjct: 180 NPEVIDLIEMKPTSIEKE-----TFPILVEE-KQLYSFDLEGFWMDVGQPKDFLSGTVLY 233
Query: 232 LKTKLKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTS 291
L + K P ++ G + + I KI +IGP+ I P +
Sbjct: 234 LNSLAKRQ-------------PKKLATGANIVGNALIDPTAKISSTAKIGPDVVIGPNVT 280
Query: 292 IGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLG 333
IGD V I S+++ NS + + V +IVG N+ +G
Sbjct: 281 IGD------GVRITRSVVLCNSTIKNHSLVKSTIVGWNSTVG 316
>gb|AAC39498.1| (U89991) mannose-1-phosphate guanylyltransferase [Hypocrea
jecorina]
Length = 364
Score = 136 bits (338), Expect = 6e-31
Identities = 110/343 (32%), Positives = 170/343 (49%), Gaps = 34/343 (9%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENL-DPFVDEFIIIVKYMKEKI 59
MK ++L G G RLRPLT PKP+++ NKP+I + +E L V + ++ V Y E +
Sbjct: 1 MKGLILVGGFGTRLRPLTLTLPKPLVEFCNKPMIVHQIEALVAAGVTDIVLAVNYRPEIM 60
Query: 60 IETLG--DEFHGKPITYVSQVEEEGTAKAIYSAKDYI--EEEEFFAINGDIYFEQEAIRG 115
+ L +E + I + + E TA + A+ + ++ FF +N D+ + +
Sbjct: 61 EKFLAEYEEKYNINIEFSVESEPLDTAGPLKLAERILGKDDSPFFVLNSDVICDY-PFKE 119
Query: 116 LLHVYKKTKANAALVVKKFDDLSQLGMVKTEGGY---VREIVEKPGN-VGGLANLGIYIF 171
LL +K +VV K ++ S+ G+V + + + VEKP VG N G+YIF
Sbjct: 120 LLEFHKAHGDEGTIVVTKVEEPSKYGVVVHKPNHPSRIDRFVEKPVEFVGNRINAGMYIF 179
Query: 172 NPDVFEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYI 231
NP V + IE S E T M++D ++ F+ GFW D+G+P D L
Sbjct: 180 NPSVLKRIELRPTSIEKE-----TFPAMVAD-NQLHSFDLEGFWMDVGQPKDFLSGTCLY 233
Query: 232 LKTKLKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGP-VKIGKNCRIGPNCFIRPYT 290
L + K +G+ E + PP E V G+ +I P KIGKNCRIGPN I P
Sbjct: 234 LSSLTK---KGSKE----LTPPTE----PYVHGGNVMIHPSAKIGKNCRIGPNVTIGPDV 282
Query: 291 SIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLG 333
+GD + V +K S + D++ +V +IVG N+ +G
Sbjct: 283 VVGDGVRLQRCVLLKGSKVKDHA------WVKSTIVGWNSTVG 319
>gb|AAC64912.1| (AF030300) putative GDP-mannose pyrophosphorylase [Candida
albicans]
Length = 362
Score = 135 bits (337), Expect = 8e-31
Identities = 104/365 (28%), Positives = 176/365 (47%), Gaps = 40/365 (10%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPF-VDEFIIIVKYMKEKI 59
MK ++L G G RLRPLT PKP+++ N+P+I + +E L V + ++ V Y E +
Sbjct: 1 MKGLILVGGYGTRLRPLTLTLPKPLVEFGNRPMILHQIEALAAAGVTDIVLAVNYRPEVM 60
Query: 60 IETLG--DEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEE--FFAINGDIYFEQEAIRG 115
+ TL +E +G IT+ + E GTA + A++ +++++ FF +N D+ + +
Sbjct: 61 VSTLKKYEEEYGVSITFSVEEEPLGTAGPLKLAEEVLKKDDSPFFVLNSDVICDY-PFKE 119
Query: 116 LLHVYKKTKANAALVVKKFDDLSQLGMV---KTEGGYVREIVEKPGN-VGGLANLGIYIF 171
L +K A +V K D+ S+ G++ + + VEKP VG N G+YI
Sbjct: 120 LADFHKAHGAAGTIVATKVDEPSKYGVIVHDRDTPNLIDRFVEKPVEFVGNRINAGLYIL 179
Query: 172 NPDVFEFIE-RTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLE-VNE 229
NP V + IE R E+ + I + + +++ F+ G+W D+G+P D L
Sbjct: 180 NPSVIDLIEMRPTSIEKDPFPI-------LVEQKQLYSFDLEGYWMDVGQPKDFLSGTCL 232
Query: 230 YILKTKLKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPY 289
Y+ KH P ++ + V G+ +I P +I P+ I P
Sbjct: 233 YLTSLSKKH--------------PEKLCKEKYVHGGNVLIDP-----TAKIHPSALIGPN 273
Query: 290 TSIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLG--AGTITANLRHDNRT 347
+IG N +G I+ S+++ NS +V +IVG N+ +G A T + D+
Sbjct: 274 VTIGPNVVVGEGARIRRSVLLANSQVKDHAWVKSTIVGWNSRIGKWARTEGVTVLGDDVQ 333
Query: 348 IKVEI 352
+K EI
Sbjct: 334 VKNEI 338
>gb|AAC64911.1| (AF030299) putative GDP-mannose pyrophosphorylase [Candida
albicans]
Length = 362
Score = 135 bits (336), Expect = 1e-30
Identities = 104/365 (28%), Positives = 176/365 (47%), Gaps = 40/365 (10%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPF-VDEFIIIVKYMKEKI 59
MK ++L G G RLRPLT PKP+++ N+P+I + +E L V + ++ V Y E +
Sbjct: 1 MKGLILVGGYGTRLRPLTLTLPKPLVEFGNRPMILHQIEALAAAGVTDIVLAVNYRPEVM 60
Query: 60 IETLG--DEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEE--FFAINGDIYFEQEAIRG 115
+ TL +E +G IT+ + E GTA + A++ +++++ FF +N D+ + +
Sbjct: 61 VSTLKKYEEEYGVSITFSVEEEPLGTAGPLKLAEEVLKKDDSPFFVLNSDVICDY-PFKE 119
Query: 116 LLHVYKKTKANAALVVKKFDDLSQLGMV---KTEGGYVREIVEKPGN-VGGLANLGIYIF 171
L +K A +V K D+ S+ G++ + + VEKP VG N G+YI
Sbjct: 120 LADFHKAHGAAGTIVATKVDEPSKYGVIVHDRDTPNLIDRFVEKPVEFVGNRINAGLYIL 179
Query: 172 NPDVFEFIE-RTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLE-VNE 229
NP V + IE R E+ + I + + +++ F+ G+W D+G+P D L
Sbjct: 180 NPSVIDLIEMRPTSIEKDPFPI-------LVEQKQLYSFDLEGYWMDVGQPKDFLSGTCL 232
Query: 230 YILKTKLKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPY 289
Y+ KH P ++ + V G+ +I P +I P+ I P
Sbjct: 233 YLTSLSKKH--------------PEKLCKEKYVHGGNVLIDP-----TAKIHPSALIGPN 273
Query: 290 TSIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLG--AGTITANLRHDNRT 347
+IG N +G I+ S+++ NS +V +IVG N+ +G A T + D+
Sbjct: 274 VTIGPNVVVGEGARIQRSVLLANSQVKDHAWVKSTIVGWNSRIGKWARTEGVTVLGDDVQ 333
Query: 348 IKVEI 352
+K EI
Sbjct: 334 VKNEI 338
>dbj|BAA34807.1| (AB020596) GDP-mannose pyrophosphorylase [Candida albicans]
Length = 362
Score = 135 bits (336), Expect = 1e-30
Identities = 104/364 (28%), Positives = 176/364 (47%), Gaps = 38/364 (10%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPF-VDEFIIIVKYMKEKI 59
MK ++L G G RLRPLT PKP+++ N+P+I + +E L V + ++ V Y E +
Sbjct: 1 MKGLILVGGYGTRLRPLTLTLPKPLVEFGNRPMILHQIEALAAAGVTDIVLAVNYRPEVM 60
Query: 60 IETLG--DEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEE--FFAINGDIYFEQEAIRG 115
+ TL +E +G IT+ + E GTA + A++ +++++ FF +N D+ + +
Sbjct: 61 VSTLKKYEEEYGVSITFSVEEEPLGTAGPLKLAEEVLKKDDSPFFVLNSDVICDY-PFKE 119
Query: 116 LLHVYKKTKANAALVVKKFDDLSQLGMV---KTEGGYVREIVEKPGN-VGGLANLGIYIF 171
L +K A +V K D+ S+ G++ + + VEKP VG N G+YI
Sbjct: 120 LADFHKAHGAAGTIVATKVDEPSKYGVIVHDRDTPNLIDRFVEKPVEFVGNRINAGLYIL 179
Query: 172 NPDVFEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLE-VNEY 230
NP V + IE S E T +++ + +++ F+ G+W D+G+P D L Y
Sbjct: 180 NPSVIDLIEMRPTSIEKE-----TFPILV-EQKQLYSFDLEGYWMDVGQPKDFLSGTCLY 233
Query: 231 ILKTKLKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYT 290
+ KH P ++ + V G+ +I P +I P+ I P
Sbjct: 234 LTSLSKKH--------------PEKLCKEKYVHGGNVLIDP-----TAKIHPSALIGPNV 274
Query: 291 SIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLG--AGTITANLRHDNRTI 348
+IG N +G I+ S+++ NS +V +IVG N+ +G A T + D+ +
Sbjct: 275 TIGPNVVVGEGARIQRSVLLANSQVKDHAWVKSTIVGWNSRIGKWARTEGVTVLGDDVEV 334
Query: 349 KVEI 352
K EI
Sbjct: 335 KNEI 338
>dbj|BAB03784.1| (AP001507) UDP-N-acetylglucosamine pyrophosphorylase [Bacillus
halodurans]
Length = 455
Score = 134 bits (335), Expect = 1e-30
Identities = 123/474 (25%), Positives = 208/474 (42%), Gaps = 90/474 (18%)
Query: 3 AVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPF-VDEFIIIVKYMKEKIIE 61
AV+LAAG+G R++ K + V KP+++++++ + DE + I+ + + +
Sbjct: 6 AVILAAGQGTRMK---SKLYKVLHSVCGKPMVQHVVDQVSALGFDEIVTIIGHGADAVKS 62
Query: 62 TLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAIN--GDI-YFEQEAIRGLLH 118
LG+ ++Y Q E+ GT A+ A+ + I GD E I ++
Sbjct: 63 QLGER-----VSYALQEEQLGTGHAVLQAESALGGRRGVTIVLCGDTPLLTAETIDHVMS 117
Query: 119 VYKKTKANAALVVKKFDDLSQLG-MVKTEGGYVREIVEKPGNVGGL-----ANLGIYIF- 171
+++ +A A ++ + D + G +V+ + G V IVE N G Y F
Sbjct: 118 YHEEEQAKATVLTAELADPTGYGRIVRNDKGLVERIVEHKDATSEEKQITEVNTGTYCFD 177
Query: 172 NPDVFEFIERT-QESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEY 230
N +F+ ++ + +GEY + D I ++ + G KVA ++ + +G VN+
Sbjct: 178 NEALFQALKEVGNNNAQGEYYLPDVIQILQTKGEKVAAYKTAHVEETLG-------VNDR 230
Query: 231 ILKTKLKHDIRGTVEE-----GATIIPPVE--------IGEGTVVRSGSYIIGPVKIGKN 277
+ + + ++ + E G T I P + IG+ TV+ G+ ++G IG+
Sbjct: 231 VALAQAEQVMKRRINEAWMRKGVTFIDPEQTYVSPDATIGQDTVIYPGTMVLGQTTIGEG 290
Query: 278 C---------------------------------RIGPNCFIRPYTSIGDNCHIGNAVEI 304
C IGP IRP + I D+ IGN VE+
Sbjct: 291 CVLGPHTELKDSKIGNKTAVKQSVVHNSEVGERVSIGPFSHIRPASMIHDDVRIGNFVEV 350
Query: 305 KNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTITANLRHDNRTIKVEIKGKLEDSGRRKL 364
K S I S A HL+Y+GD+ VGE N G+IT N N+ + K+ED
Sbjct: 351 KKSTIGKESKASHLSYIGDAEVGERVNFSCGSITVNYDGKNKFLT-----KIEDD----- 400
Query: 365 GAIIGHNVKTGINVTIYPGRKIGSGALVGPGVIVDKNIPPNVLVVAKQEKIVKE 418
A IG N VT IG GAL+ G + +++P + L +A+ + KE
Sbjct: 401 -AFIGCNSNLIAPVT------IGKGALIAAGSTITEDVPSDALSIARARQTNKE 447
>pir||T42371 probable mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) -
fission yeast (Schizosaccharomyces pombe)
>gi|1749464|dbj|BAA13790.1| (D89128) similar to
Saccharomyces cerevisiae putative NDP-hexose
pyrophosphopylase, SWISS-PROT Accession Number P41940
[Schizosaccharomyces pombe]
Length = 363
Score = 134 bits (334), Expect = 2e-30
Identities = 108/351 (30%), Positives = 168/351 (47%), Gaps = 36/351 (10%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPF-VDEFIIIVKYMKEKI 59
MKA++L G G RLRPLT PKP+++ NKP+I + +E L V + ++ V Y E +
Sbjct: 1 MKALILVGGFGTRLRPLTLTLPKPLVEFGNKPMILHQVEALAAAGVTDIVLAVNYRPEIM 60
Query: 60 IETLG--DEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEE--FFAINGDIYFEQEAIRG 115
+E L ++ + IT+ + E GTA + A+D + ++ FF +N D+ E
Sbjct: 61 VEALKKYEKEYNVNITFSVENEPLGTAGPLALARDILAKDHSPFFVLNSDVICEYP-FAD 119
Query: 116 LLHVYKKTKANAALVVKKFDDLSQLGMV---KTEGGYVREIVEKPGN-VGGLANLGIYIF 171
L +K A +VV K ++ S+ G+V + VEKP V N +YI
Sbjct: 120 LAAFHKAHGAEGTIVVTKVEEPSKYGVVVHYPNSESLIERFVEKPVEFVSNRINGVLYIL 179
Query: 172 NPDVFEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYI 231
NP V + IE S E M++D +++ F+ G+W D+G+P D L
Sbjct: 180 NPSVLDRIEPRPTSIEKE-----VFPAMVND-KQLHSFDLEGYWMDVGQPKDYLTGTCLY 233
Query: 232 LKTKLKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGP-VKIGKNCRIGPNCFIRPYT 290
L + KH + II G+ +I P IGKNC+IGPN I P
Sbjct: 234 LSSLRKHKPEILAPASSNII-------------GNVLIDPSATIGKNCKIGPNVVIGPNV 280
Query: 291 SIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTITANL 341
+IGD + +K+S + D++ +V SIVG N+ LG+ + N+
Sbjct: 281 TIGDGVRLQRCAILKSSRVRDHA------WVKSSIVGWNSTLGSWSRLENV 325
>sp|P17114|GLMU_ECOLI UDP-N-ACETYLGLUCOSAMINE PYROPHOSPHORYLASE
(N-ACETYLGLUCOSAMINE-1-PHOSPHATE URIDYLTRANSFERASE)
>gi|7448097|pir||C65176 glmU protein - Escherichia coli
(strain K-12) >gi|1790168|gb|AAC76753.1| (AE000450)
N-acetyl glucosamine-1-phosphate uridyltransferase
[Escherichia coli K12]
Length = 456
Score = 134 bits (334), Expect = 2e-30
Identities = 120/468 (25%), Positives = 204/468 (42%), Gaps = 76/468 (16%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPFVDEFI-IIVKYMKEKI 59
M V+LAAGKG R+ D PK + +A K +++++++ + + ++ + + +
Sbjct: 6 MSVVILAAGKGTRMY---SDLPKVLHTLAGKAMVQHVIDAANELGAAHVHLVYGHGGDLL 62
Query: 60 IETLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYI-EEEEFFAINGDI-YFEQEAIRGLL 117
+ L D+ + +V Q E+ GT A+ A + ++E+ + GD+ E ++ L
Sbjct: 63 KQALKDD----NLNWVLQAEQLGTGHAMQQAAPFFADDEDILMLYGDVPLISVETLQRLR 118
Query: 118 HVYKKTKANAALVVKKFDDLSQLGMVKTEGGYVREIVEKPGNVGGLA-----NLGIYIFN 172
K + L+ K DD + G + E G V IVE N GI I N
Sbjct: 119 DA--KPQGGIGLLTVKLDDPTGYGRITRENGKVTGIVEHKDATDEQRQIQEINTGILIAN 176
Query: 173 -PDVFEFIER-TQESERGEYEITDTINLMISDGRKVA------YFEYSGF-----WSDIG 219
D+ ++ + T + +GEY ITD I L +GR++ E G S +
Sbjct: 177 GADMKRWLAKLTNNNAQGEYYITDIIALAYQEGREIVAVHPQRLSEVEGVNNRLQLSRLE 236
Query: 220 RPWDLLEVNEYI-----LKTKLKHDIRGT--------------VEEGATIIPPVEIGEGT 260
R + + + + L+ + D+RGT +E T+ V+IG G
Sbjct: 237 RVYQSEQAEKLLLAGVMLRDPARFDLRGTLTHGRDVEIDTNVIIEGNVTLGHRVKIGTGC 296
Query: 261 VVR----------SGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDNCHIGNAVEIKNSIIM 310
V++ S ++ + C IGP +RP + + H+GN VE+K + +
Sbjct: 297 VIKNSVIGDDCEISPYTVVEDANLAAACTIGPFARLRPGAELLEGAHVGNFVEMKKARLG 356
Query: 311 DNSNAPHLNYVGDSIVGENTNLGAGTITANLRHDNRTIKVEIKGKLEDSGRRKLGAIIGH 370
S A HL Y+GD+ +G+N N+GAGTIT N G K IIG
Sbjct: 357 KGSKAGHLTYLGDAEIGDNVNIGAGTITCNY-----------------DGANKFKTIIGD 399
Query: 371 NVKTGINVTIYPGRKIGSGALVGPGVIVDKNIPPNVLVVAKQEKIVKE 418
+V G + + +G GA + G V +N+ N L +++ + KE
Sbjct: 400 DVFVGSDTQLVAPVTVGKGATIAAGTTVTRNVGENALAISRVPQTQKE 447
>pir||H75070 sugar-phosphate nucleotydyl transferase PAB0645 - Pyrococcus abyssi
(strain Orsay) >gi|5458381|emb|CAB49869.1| (AJ248286)
SUGAR-PHOSPHATE NUCLEOTYDYL TRANSFERASE [Pyrococcus
abyssi]
Length = 413
Score = 134 bits (333), Expect = 2e-30
Identities = 105/344 (30%), Positives = 164/344 (47%), Gaps = 25/344 (7%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPF--VDEFIIIVKYMKEK 58
MKAV+LA G G RLRP++ RPKP++ V KP ++YILE L+ +DE I+ V YM+ +
Sbjct: 1 MKAVILAGGFGTRLRPISSTRPKPMVPVLGKPNLQYILEALEKVKEIDEVILSVHYMRGE 60
Query: 59 IIETLGDEF--HGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGL 116
I E + ++ + K I +V+ T A+ + ++Y+ ++F I GD+ F L
Sbjct: 61 IREFIQEKMRDYPKDIRFVNDPMPLETGGALKNVEEYV-SDDFLVIYGDV-FTNFDYSEL 118
Query: 117 LHVYKKTKANAALVVKKFDDLSQLGMVKT-EGGYVREIVEKPGN-VGGLANLGIYIFNPD 174
+ +KK + + K D + G+V T E G + E EKP L + GIY+ N D
Sbjct: 119 IEAHKKNDGLVTVALTKVYDPERFGVVITDEEGKIVEFEEKPRKPKTNLVDAGIYMVNKD 178
Query: 175 VFEFIERTQESERGEYEITDTINLMISDGRKVAY-FEYSGFWSDIGRPWDLLEVNEYILK 233
V + I + +E Y + + +S G Y +W D+G P D ++ L
Sbjct: 179 VLKEIPKNKE----VYFEREILPKFVSQGLVYGYKMPKHYYWVDLGTPEDFFYAHQIALD 234
Query: 234 TKLKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIG 293
+ E G I +GE + + GPV I N +IG I+ YT IG
Sbjct: 235 EMAR-------ENGYMI-----LGENVEIPEDVEVQGPVYIDDNAKIGHGVKIKAYTYIG 282
Query: 294 DNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTI 337
N I + IK +I++ N + D+I+GE +G I
Sbjct: 283 PNTMIEDKAYIKRAILLGNDIIKERAELKDTILGEGVVVGKNVI 326
>emb|CAA25784.1| (X01631) Eco urf 1 protein [Escherichia coli]
Length = 456
Score = 133 bits (332), Expect = 3e-30
Identities = 120/468 (25%), Positives = 203/468 (42%), Gaps = 76/468 (16%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPFVDEFI-IIVKYMKEKI 59
M V+LAAGKG R+ D PK + +A K +++++++ + + ++ + + +
Sbjct: 6 MSVVILAAGKGTRMY---SDLPKVLHTLAGKAMVQHVIDAANELGAAHVHLVYGHGGDLL 62
Query: 60 IETLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYI-EEEEFFAINGDI-YFEQEAIRGLL 117
+ L D+ + +V Q E+ GT A+ A + ++E+ + GD+ E ++ L
Sbjct: 63 KQALKDD----NLNWVLQAEQLGTGHAMQQAAPFFADDEDILMLYGDVPLISVETLQRLR 118
Query: 118 HVYKKTKANAALVVKKFDDLSQLGMVKTEGGYVREIVEKPGNVGGLA-----NLGIYIFN 172
K + L+ K DD + G + E G V IVE N GI I N
Sbjct: 119 DA--KPQGGIGLLTVKLDDPTGYGRITRENGKVTGIVEHKDATDEQRQIQEINTGILIAN 176
Query: 173 -PDVFEFIER-TQESERGEYEITDTINLMISDGRKVA------YFEYSGF-----WSDIG 219
D+ ++ T + +GEY ITD I L +GR++ E G S +
Sbjct: 177 GADMKRWLANVTNNNAQGEYYITDIIALAYQEGREIVAVHPQRLSEVEGVNNRLQLSRLE 236
Query: 220 RPWDLLEVNEYI-----LKTKLKHDIRGT--------------VEEGATIIPPVEIGEGT 260
R + + + + L+ + D+RGT +E T+ V+IG G
Sbjct: 237 RVYQSEQAEKLLLAGVMLRDPARFDLRGTLTHGRDVEIDTNVIIEGNVTLGHRVKIGTGC 296
Query: 261 VVR----------SGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDNCHIGNAVEIKNSIIM 310
V++ S ++ + C IGP +RP + + H+GN VE+K + +
Sbjct: 297 VIKNSVIGDDCEISPYTVVEDANLAAACTIGPFARLRPGAELLEGAHVGNFVEMKKARLG 356
Query: 311 DNSNAPHLNYVGDSIVGENTNLGAGTITANLRHDNRTIKVEIKGKLEDSGRRKLGAIIGH 370
S A HL Y+GD+ +G+N N+GAGTIT N G K IIG
Sbjct: 357 KGSKAGHLTYLGDAEIGDNVNIGAGTITCNY-----------------DGANKFKTIIGD 399
Query: 371 NVKTGINVTIYPGRKIGSGALVGPGVIVDKNIPPNVLVVAKQEKIVKE 418
+V G + + +G GA + G V +N+ N L +++ + KE
Sbjct: 400 DVFVGSDTQLVAPVTVGKGATIAAGTTVTRNVGENALAISRVPQTQKE 447
>gb|AAD01737.1| (AF022716) GDP-mannose pyrophosphorylase [Solanum tuberosum]
Length = 361
Score = 133 bits (332), Expect = 3e-30
Identities = 105/351 (29%), Positives = 161/351 (44%), Gaps = 37/351 (10%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPF-VDEFIIIVKYMKEKI 59
MKA++L G G RLRPLT PKP+++ ANKP+I + +E L V E ++ + Y E +
Sbjct: 1 MKALILVGGFGTRLRPLTLSVPKPLVEFANKPMILHQIEALKAVGVTEVVLAINYQPEVM 60
Query: 60 IETLGDEFH---GKPITYVSQVEEEGTAKAIYSAKDYIEE---EEFFAINGDIYFEQEAI 113
+ L EF G IT + E GTA + A+D + + E FF +N D+ E
Sbjct: 61 LNFL-KEFEASLGIKITCSQETEPLGTAGPLALARDKLIDDSGEPFFVLNSDVISEYP-F 118
Query: 114 RGLLHVYKKTKANAALVVKKFDDLSQLGMVKTEG--GYVREIVEKPGN-VGGLANLGIYI 170
+ ++ +K A+L+V K D+ S+ G+V E G V VEKP VG N G Y+
Sbjct: 119 KEMIQFHKSHGGEASLMVTKVDEPSKYGVVVMEESTGQVERFVEKPKLFVGNKINAGFYL 178
Query: 171 FNPDVFEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEY 230
NP V + I+ S I + I+ +K+ GFW DIG+P D +
Sbjct: 179 LNPSVLDRIQLRPTS------IEKEVFPKIAAEKKLYAMVLPGFWMDIGQPRDYITGLRL 232
Query: 231 ILKTKLKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYT 290
L + KH + SG +I+G V + ++ +IG C I P
Sbjct: 233 YLDSLKKHS-------------------SPKLASGPHIVGNVIVDESAKIGEGCLIGPDV 273
Query: 291 SIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTITANL 341
+IG C I + V + +M + SI+G ++ +G N+
Sbjct: 274 AIGSGCVIESGVRLSRCTVMRGVRIKKHACISGSIIGWHSTVGQWARVENM 324
>pir||B72041 udp-glcnac pyrophosphorylase - Chlamydophila pneumoniae (strain
CWL029) >gi|4377055|gb|AAD18887.1| (AE001656) UDP-GlcNAc
Pyrophosphorylase [Chlamydophila pneumoniae CWL029]
>gi|8979122|dbj|BAA98957.1| (AP002547) UDP-GlcNAc
pyrophosphorylase [Chlamydophila pneumoniae J138]
Length = 208
Score = 133 bits (331), Expect = 4e-30
Identities = 74/195 (37%), Positives = 103/195 (51%), Gaps = 5/195 (2%)
Query: 209 FEYSGFWSDIGRPWDLLEVNEYILKTKLKHDIRGTVEEGATI--IPPVEIGEGTVVRSGS 266
F Y S WD+L++ + +L+ + I GTVE G T+ I +EI E V SG+
Sbjct: 14 FLYPEIISKAHYTWDILDLMDQMLENHVFSGIHGTVESGVTLKNIEKIEIAEDAYVESGA 73
Query: 267 YIIGPVKIGKNCRIGPNCFIRPYTSIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIV 326
YI+GP +G + ++R G C +G+ EIKNS + ++ A H Y+GDS++
Sbjct: 74 YIVGPCILGSQTEVRHGAYLRGNVITGSRCVVGHCTEIKNSYLGHHTKAAHFAYLGDSVL 133
Query: 327 GENTNLGAGTITANLRHDNRTIKVEI---KGKLEDSGRRKLGAIIGHNVKTGINVTIYPG 383
NLGAG AN R D R I V K K D+GRRKLGA +G V G NV I PG
Sbjct: 134 SSEVNLGAGVRCANFRLDGRNIYVRSTSDKSKKIDTGRRKLGAFLGKGVAIGCNVVINPG 193
Query: 384 RKIGSGALVGPGVIV 398
+ I + PG ++
Sbjct: 194 QHILPHTRIRPGQVI 208
>emb|CAB79775.1| (AL161577) GDP-mannose pyrophosphorylase like protein [Arabidopsis
thaliana]
Length = 351
Score = 133 bits (331), Expect = 4e-30
Identities = 104/343 (30%), Positives = 164/343 (47%), Gaps = 36/343 (10%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENL-DPFVDEFIIIVKYMKEKI 59
+KA++L G G RLRPLT PKP++ NKP+I + +E L V E ++ + + + ++
Sbjct: 1 LKALILVGGFGTRLRPLTLSMPKPLVDFGNKPMILHQIEALKGAGVTEVVLAINHQQPEV 60
Query: 60 IETLGDEFHGK---PITYVSQVEEEGTAKAIYSAKDYIEEEE---FFAINGDIYFEQEAI 113
+ E+ K IT+ + E GTA + A+D + +E FF +N D+ E +
Sbjct: 61 MLNFVKEYEKKLEIKITFSQETEPLGTAGPLALARDKLVDESGQPFFVLNSDVICEYPLL 120
Query: 114 RGLLHVYKKTKANAALVVKKFDDLSQLGMVKTEGGYVR--EIVEKPGN-VGGLANLGIYI 170
++ +K +A A+++V + DD S+ G+V TE G R VEKP + VG N GIY+
Sbjct: 121 E-MIEFHKTNRAEASIMVTEVDDPSKYGVVVTEEGTARVESFVEKPKHFVGNKINAGIYL 179
Query: 171 FNPDVFEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEY 230
+P V + IE + S I I I+ +K+ GFW DIG+P D +
Sbjct: 180 LSPSVLDRIELRRTS------IEKEIFPKIASEKKLYAMVLPGFWMDIGQPKDYITGQRM 233
Query: 231 ILKTKLKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYT 290
L + + T +E AT G IIG V + ++ IG C I P
Sbjct: 234 YLNSLREK----TPQELAT---------------GDNIIGNVLVHESAVIGEGCLIGPDV 274
Query: 291 SIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLG 333
IG C I + V + +M + +SIVG ++ +G
Sbjct: 275 VIGPGCVIDSGVRLFGCTVMRGVWIKEHACISNSIVGWDSTVG 317
>pir||A71095 probable sugar-phosphate nucleotydyl transferase - Pyrococcus
horikoshii >gi|3257436|dbj|BAA30119.1| (AP000004) 416aa
long hypothetical sugar-phosphate nucleotydyl
transferase [Pyrococcus horikoshii]
Length = 416
Score = 132 bits (330), Expect = 5e-30
Identities = 106/343 (30%), Positives = 163/343 (46%), Gaps = 23/343 (6%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPF--VDEFIIIVKYMKEK 58
MKAV+LA G G RLRP++ RPKP++ V KP ++YILE L+ +DE I+ V YM+ +
Sbjct: 4 MKAVILAGGFGTRLRPISSTRPKPMVPVLGKPNLQYILEALEKVKEIDEIILSVHYMRGE 63
Query: 59 IIETLGDEF--HGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGL 116
I E + ++ + K I +V+ T A+ + ++Y+ ++F I GD+ F L
Sbjct: 64 IREFIQEKMRDYPKDIRFVNDPMPLETGGALKNVEEYV-SDDFLVIYGDV-FTNFDYSEL 121
Query: 117 LHVYKKTKANAALVVKKFDDLSQLGMVKT-EGGYVREIVEKPGN-VGGLANLGIYIFNPD 174
+ +KK + + K D + G+V T E G + E EKP L + GIY+ N D
Sbjct: 122 IEAHKKNDGLITVALTKVYDPERFGVVITDEEGKIVEFEEKPRKPKTNLVDAGIYMVNKD 181
Query: 175 VFEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKT 234
V + I + +E + +N + G K+ Y W D+G P D ++ L
Sbjct: 182 VLKEIPKNKEIYFEREILPKFVNQGLVYGYKMPKQYY---WVDLGTPEDFFYAHQIALDE 238
Query: 235 KLKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGD 294
K E G I +GE + + GPV I N +IG I+ YT IG
Sbjct: 239 LSK-------ENGYMI-----LGENVEIPDDVEVQGPVYIDDNAKIGHGVKIKAYTYIGP 286
Query: 295 NCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTI 337
N I + K SI++ N + D+I+GE +G I
Sbjct: 287 NTIIEDKAYFKRSILLGNDIIKERAELKDAILGEGVVVGKDVI 329
>pir||T01007 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) - Arabidopsis
thaliana >gi|2642159|gb|AAB87126.1| (AC003000) putative
GDP-mannose pyrophosphorylase [Arabidopsis thaliana]
>gi|3598958|gb|AAC78474.1| (AF076484) GDP-mannose
pyrophosphorylase [Arabidopsis thaliana]
>gi|4151925|gb|AAD04627.1| (AF108660) CYT1 protein
[Arabidopsis thaliana]
Length = 361
Score = 131 bits (326), Expect = 2e-29
Identities = 115/391 (29%), Positives = 180/391 (45%), Gaps = 52/391 (13%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPF-VDEFIIIVKYMKEKI 59
MKA++L G G RLRPLT PKP++ ANKP+I + +E L VDE ++ + Y E +
Sbjct: 1 MKALILVGGFGTRLRPLTLSFPKPLVDFANKPMILHQIEALKAVGVDEVVLAINYQPEVM 60
Query: 60 IETLGDEFHGK---PITYVSQVEEEGTAKAIYSAKDYIEE---EEFFAINGDIYFEQEAI 113
+ L D F K IT + E GTA + A+D + + E FF +N D+ E +
Sbjct: 61 LNFLKD-FETKLEIKITCSQETEPLGTAGPLALARDKLLDGSGEPFFVLNSDVISEYP-L 118
Query: 114 RGLLHVYKKTKANAALVVKKFDDLSQLGMVKTEG--GYVREIVEKPG-NVGGLANLGIYI 170
+ +L +K A+++V K D+ S+ G+V E G V + VEKP VG N GIY+
Sbjct: 119 KEMLEFHKSHGGEASIMVTKVDEPSKYGVVVMEESTGRVEKFVEKPKLYVGNKINAGIYL 178
Query: 171 FNPDVFEFIE-RTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNE 229
NP V + IE R E+ + I+ + + GFW DIG+P D +
Sbjct: 179 LNPSVLDKIELRPTSIEKETFP-------KIAAAQGLYAMVLPGFWMDIGQPRDYITGLR 231
Query: 230 YILKTKLKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPY 289
L + K P ++ SG +I+G V + + IG C I P
Sbjct: 232 LYLDSLRKKS-------------PAKL------TSGPHIVGNVLVDETATIGEGCLIGPD 272
Query: 290 TSIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTITANLRHDNRTI- 348
+IG C + + V + +M + SI+G ++ +G R +N TI
Sbjct: 273 VAIGPGCIVESGVRLSRCTVMRGVRIKKHACISSSIIGWHSTVGQWA-----RIENMTIL 327
Query: 349 --KVEIKGKLEDSGRRKLGAIIGH-NVKTGI 376
V + ++ +G G ++ H +K+ I
Sbjct: 328 GEDVHVSDEIYSNG----GVVLPHKEIKSNI 354
>sp|P43889|GLMU_HAEIN UDP-N-ACETYLGLUCOSAMINE PYROPHOSPHORYLASE
(N-ACETYLGLUCOSAMINE-1-PHOSPHATE URIDYLTRANSFERASE)
>gi|1075420|pir||G64083 glmU protein homolog -
Haemophilus influenzae (strain Rd KW20)
>gi|1573640|gb|AAC22302.1| (U32747)
UDP-N-acetylglucosamine pyrophosphorylase (glmU)
[Haemophilus influenzae Rd]
Length = 456
Score = 131 bits (325), Expect = 2e-29
Identities = 121/462 (26%), Positives = 203/462 (43%), Gaps = 78/462 (16%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPFVDEFIIIVKYMKEKII 60
+ AV+LAAGKG R+ D PK + +A KP+++++++ E I ++ ++
Sbjct: 6 LSAVILAAGKGTRMY---SDLPKVLHTIAGKPMVKHVIDTAHQLGSENIHLIYGHGGDLM 62
Query: 61 ETLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEE-FFAINGDI-YFEQEAIRGLLH 118
T + + +V Q E+ GTA A+ A + ++ E + GD +E + L+
Sbjct: 63 RT---HLANEQVNWVLQTEQLGTAHAVQQAAPFFKDNENIVVLYGDAPLITKETLEKLIE 119
Query: 119 VYKKTKANAALVVKKFDDLSQLGMVKTEGGYVREIVE-KPGNVGGL----ANLGIYIFNP 173
K + AL+ D+ + G + E G V IVE K N L N G+ + +
Sbjct: 120 A--KPENGIALLTVNLDNPTGYGRIIRENGNVVAIVEQKDANAEQLNIKEVNTGVMVSDG 177
Query: 174 DVFE-FIERT-QESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIG-----------R 220
F+ ++ R + +GEY +TD I L D +V + + G R
Sbjct: 178 ASFKKWLARVGNNNAQGEYYLTDLIALANQDNCQVVAVQATDVMEVEGANNRLQLAALER 237
Query: 221 PWDLLEVNEYILKTKL-----KHDIRGTVEEGATII--------------PPVEIGEGTV 261
+ + ++ +L+ + + D+RGT+E G + V+IG G V
Sbjct: 238 YFQNKQASKLLLEGVMIYDPARFDLRGTLEHGKDVEIDVNVIIEGNVKLGDRVKIGTGCV 297
Query: 262 VRSGSYIIG---PVK---------IGKNCRIGPNCFIRPYTSIGDNCHIGNAVEIKNSII 309
+++ +IG +K +G+ IGP +RP + H+GN VEIK S +
Sbjct: 298 LKN--VVIGNDVEIKPYSVLEDSIVGEKAAIGPFSRLRPGAELAAETHVGNFVEIKKSTV 355
Query: 310 MDNSNAPHLNYVGDSIVGENTNLGAGTITANLRHDNRTIKVEIKGKLEDSGRRKLGAIIG 369
S HL YVGDS +G N N+GAG IT N G K IIG
Sbjct: 356 GKGSKVNHLTYVGDSEIGSNCNIGAGVITCNY-----------------DGANKFKTIIG 398
Query: 370 HNVKTGINVTIYPGRKIGSGALVGPGVIVDKNIPPNVLVVAK 411
+V G + + K+ +GA +G G + +++ N LV+ +
Sbjct: 399 DDVFVGSDTQLVAPVKVANGATIGAGTTITRDVGENELVITR 440
>sp|P57139|GLMU_BUCAI UDP-N-ACETYLGLUCOSAMINE PYROPHOSPHORYLASE
(N-ACETYLGLUCOSAMINE-1-PHOSPHATE URIDYLTRANSFERASE)
>gi|10038719|dbj|BAB12754.1| (AP001118)
UDP-N-acetylglucosamine pyrophosphorylase [Buchnera sp.
APS]
Length = 459
Score = 131 bits (325), Expect = 2e-29
Identities = 121/463 (26%), Positives = 200/463 (43%), Gaps = 72/463 (15%)
Query: 4 VVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPFVDEFIIIVKYMKEKIIETL 63
V+LAAGKG R++ + PK + + K I+E+++E + II+V ++K + +
Sbjct: 9 VILAAGKGTRMK---SNHPKVLHFLGGKTILEHVIETAQSIKPKKIILVYSDQKKPVLS- 64
Query: 64 GDEFHGKPITYVSQVEEEGTAKAIYSA-KDYIEEEEFFAINGDIYFEQEAIRGLLHVYKK 122
+ PI ++ Q + +GT AI A K + E + GD+ F L KK
Sbjct: 65 --NIYNIPIQWIIQKKPQGTGHAILLAIKKISDNTEILVLYGDVPFISPVSIKKLQKSKK 122
Query: 123 TKANAALVVKKFDDLSQLGMVKTEGGYVREIVEKPGNVGGLANL-----GIYIF-NPDVF 176
++ +L+ K + + G + + G V I+E N+ GI+I + D+
Sbjct: 123 -QSKISLLTAKVKNPNGYGRILRKKGKVISIIEDQDASNEQKNIKEIYSGIFIAQSKDLT 181
Query: 177 EFIERT-QESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIG---------------- 219
++++ +++E+ E+ TD I L +G + E + +G
Sbjct: 182 RWLKKIDKKNEKQEFYATDIIALAHLEGSFIKTIEPLNYEEILGINNKLQLSNLEKIFQK 241
Query: 220 RPWDLLEVNEYILKTKLKHDIRGTVEEGATII--------------PPVEIGEGTVVRSG 265
+ + L +N +K RGT++ G + V+IG G ++R+
Sbjct: 242 KQINKLLINGVTIKDPSHFIFRGTLQHGQNVEIDTGVILENNVILGDDVKIGPGCIIRNS 301
Query: 266 SY----------IIGPVKIGKNCRIGPNCFIRPYTSIGDNCHIGNAVEIKNSIIMDNSNA 315
S II KIGK C IGP +R T + N HIGN VE K++ I + S
Sbjct: 302 SIDSNTNIQAYTIIENSKIGKGCIIGPFAHLRSNTLLDRNVHIGNFVETKDTFIKNESKV 361
Query: 316 PHLNYVGDSIVGENTNLGAGTITANLRHDNRTIKVEIKGKLEDSGRRKLGAIIGHNVKTG 375
HL+Y+G+S +G N+GAG+IT N G K IIG NV G
Sbjct: 362 KHLSYLGNSEIGSKVNIGAGSITCNY-----------------DGANKFKTIIGDNVLVG 404
Query: 376 INVTIYPGRKIGSGALVGPGVIVDKNIPPNVLVVAKQEKIVKE 418
N + KI + G V K++ LV +E+ K+
Sbjct: 405 SNTQLIAPIKIAKNTTIAAGTTVTKDVNTPCLVYNTKEQKYKK 447
>pir||S76785 hypothetical protein - Synechocystis sp. (strain PCC 6803)
>gi|1653786|dbj|BAA18697.1| (D90916) mannose-1-phosphate
guanyltransferase [Synechocystis sp.]
Length = 843
Score = 130 bits (323), Expect = 4e-29
Identities = 107/409 (26%), Positives = 189/409 (46%), Gaps = 46/409 (11%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPF-VDEFIIIVKYMKEKI 59
M+AV++A G G RLRPLT D PKP++ + N+PI +I+ L + E + + Y+ + +
Sbjct: 1 MRAVLMAGGAGTRLRPLTCDLPKPMVPIVNQPIAAHIIHLLRRHNITEVVATLHYLPDAM 60
Query: 60 IETL--GDEFHGKPITYVSQVEEE---GTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIR 114
+ G EF G +TY VE+E GTA + + ++ + ++ F I+GD + +
Sbjct: 61 RDYFLDGSEF-GVQMTYA--VEDEHPLGTAGCVKNIEELL-DDTFLVISGDSITDFNLTQ 116
Query: 115 GLLHVYKKTKANAALVVKKFDDLSQLGMVKT-EGGYVREIVEKPGN---VGGLANLGIYI 170
+ +K+ +A A L++ K + + G+V T E V+ +EKP N G YI
Sbjct: 117 AIA-FHKQKQAKATLILTKVPNPLEFGVVITDENQRVQRFLEKPSTSEVFSDTVNTGTYI 175
Query: 171 FNPDVFEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEY 230
P+V ++ +E + + D L++ + + F G+W D+G E
Sbjct: 176 LEPEVLAYLPPKEEMDFSK----DLFPLLLENDEPMYGFVADGYWCDVGNLDAYREAQYD 231
Query: 231 ILKTKLKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYT 290
L+ K+ ++ + IGE T + + + P+ IG NC IG + T
Sbjct: 232 ALEKKVTLELGNLPRHS-----DIWIGENTTIDPTAILTPPLAIGDNCNIGSGTKLEAGT 286
Query: 291 SIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTITANLRHDNRTIKV 350
IGDN IG E+K +I+ + ++G+ L A + R + R +
Sbjct: 287 IIGDNVTIGAGAELKRAIVWNG-----------VLIGDEAYLAACVVGRGCRIERRVQVL 335
Query: 351 E--IKGKLEDSGRRKLGAIIGHNVKTGINVTIYPGRKIGSGALVGPGVI 397
E + G L +IIG + NV ++P +++ GA++ +I
Sbjct: 336 EGAVIGPL---------SIIGEEAQINSNVKVWPSKRVEPGAILNINLI 375
>dbj|BAB07043.1| (AP001518) glucose-1-phosphate thymidylyltransferase [Bacillus
halodurans]
Length = 463
Score = 130 bits (323), Expect = 4e-29
Identities = 117/457 (25%), Positives = 200/457 (43%), Gaps = 48/457 (10%)
Query: 3 AVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPFVDEFIIIVKYMKEKIIET 62
A++LAAGKG+++ P D PK L + N+ I +++ +L E III + I++
Sbjct: 4 AIILAAGKGKKMWPYNDYWPKAALPIGNQGNIVHLVNHLKSLAFERIIITTCYLSRRIKS 63
Query: 63 LGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLLHVYKK 122
L + G I +S E GTA + +++ F + GDI+ +E + + Y+K
Sbjct: 64 LIYDVEGVEIIELSATE--GTADTLEKVVYDLQDSNLFILYGDIFITRERLSSFIEAYEK 121
Query: 123 TKA--NAALVVKKFDD---LSQLGMVKTEGGYVREIVEKPG------NVGGLANLGIYIF 171
+ +A ++ K ++ G+ + V I P V G L +
Sbjct: 122 QRETMDAVILSKPIENEHAQDWFGIKVGKDNRVENIFGHPRPHYVQERVMGAFALNTNVL 181
Query: 172 ------NPDVFEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLL 225
NP + + T + E E+ + ++ G V+ + + D+ +PW L+
Sbjct: 182 KKMLNHNPGFMKSVP-TGVMPQQEVELEQCLQWLVEVGYNVSSYPVTDGVIDMDKPWHLM 240
Query: 226 EVNEYILKTKLKH-----------------DIRGTVEEG--------ATIIPPVEIGEGT 260
+ N ++ +++ H DI+G V+ G TI IG+ T
Sbjct: 241 QAN-HLAVSEMTHALNNNEIHETCEIDPTADIQGHVKLGKHVKIGKYVTIKGNAVIGDYT 299
Query: 261 VVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDNCHIGNAVEIKNSIIMDNSNAPHLNY 320
+ +G I G V IG +CRI C I P + IG+ IG+ E + + DN + H
Sbjct: 300 KIDNGVIIEGNVVIGSDCRIENYCRIGPDSVIGNKNRIGHCAEFRG-VTFDNVSFIHFGE 358
Query: 321 VGDSIVGENTNLGAGTITANLRHDNRTIKVEIKGKLEDSGRRKLGAIIGHNVKTGINVTI 380
V I+GE+T++ AG R D++ + + E +G +TGI
Sbjct: 359 VF-GIIGESTDIAAGVTVGITRFDDQPQTQIVNNRKEFPEEFGNAVYLGDFTRTGILSLY 417
Query: 381 YPGRKIGSGALVGPGVIVDKNIPPNVLVVAKQEKIVK 417
PG K+GS ++G GV V+K++P L+ KQ I K
Sbjct: 418 MPGIKVGSNCVIGSGVAVEKDVPSKTLLYNKQTLIEK 454
>sp|Q50986|GLMU_NEIGO UDP-N-ACETYLGLUCOSAMINE PYROPHOSPHORYLASE
(N-ACETYLGLUCOSAMINE-1-PHOSPHATE URIDYLTRANSFERASE)
>gi|975206|emb|CAA90326.1| (Z50023) uridyltransferase
[Neisseria gonorrhoeae]
Length = 456
Score = 130 bits (323), Expect = 4e-29
Identities = 123/472 (26%), Positives = 207/472 (43%), Gaps = 85/472 (18%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILEN---LDPFVDEFIIIVKYMKE 57
+ V+LAAGKG R+ PK + + KP++E +++ L+P ++V + KE
Sbjct: 6 LNTVILAAGKGTRMY---SQMPKVLHCIGGKPMVERVIDTAAALNP--QNICVVVGHGKE 60
Query: 58 KIIETLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEE-EFFAINGDI-YFEQEAIRG 115
++++T+ + +V Q E+ GT A+ +A ++ E + GD+ + E +
Sbjct: 61 QVLDTVK-----RDAVWVEQTEQLGTGHAVKTALPHLASEGRTLVLYGDVPLIDVETLET 115
Query: 116 LLHVYKKTKANAALVVKKFDDLSQLGMVKTEG-GYVREIVEKPGNVGGLA-----NLGIY 169
LL L+ D + LG + +G G V IVE+ N GI
Sbjct: 116 LLEAAGN---EVGLLTDVPADPAGLGRIIRDGSGSVTAIVEEKDASATQKTIREINTGIL 172
Query: 170 IF-NPDVFEFIER-TQESERGEYEITDTINLMISDGRKV-----------AYFEYSGFWS 216
+ N + ++ + + +GEY +TD I ++DG KV A +
Sbjct: 173 VLPNAKLENWLNSLSSNNAQGEYYLTDLIAKAVADGIKVRPVRVRASHLAAGVNNKRQLA 232
Query: 217 DIGRPWDLLEVNEYI-----LKTKLKHDIRGTVEEGATII--------------PPVEIG 257
++ R + + E + L+ + D+RG ++ G ++ VEIG
Sbjct: 233 ELERIFQTEQAQELLKAGVTLRDPARFDLRGRLKHGQDVVIDVNVVIEGEVELGDNVEIG 292
Query: 258 EGTVVRSG-----------SYIIGPVKIGKNCRIGPNCFIRPYTSIGDNCHIGNAVEIKN 306
V+++ S++ G ++G+N RIGP +RP + D+ H+GN VEIKN
Sbjct: 293 ANCVIKNAKIGANSKIAPFSHLEG-CEVGENNRIGPYARLRPQARLADDVHVGNFVEIKN 351
Query: 307 SIIMDNSNAPHLNYVGDSIVGENTNLGAGTITANLRHDNRTIKVEIKGKLEDSGRRKLGA 366
+ I + A HL Y+GD+ VG TN GAGTI AN G K
Sbjct: 352 AAIGKGTKANHLTYIGDAEVGSKTNFGAGTIIANY-----------------DGVHKHKT 394
Query: 367 IIGHNVKTGINVTIYPGRKIGSGALVGPGVIVDKNIPPNVLVVAKQEKIVKE 418
+IG V+ G N + +G+ G G + +NI N L +A+ + V E
Sbjct: 395 VIGDEVRIGSNCVLVAPVTLGNKVTTGAGSAITRNIEDNKLALARARQTVIE 446
>pir||D82036 UDP-N-acetylglucosamine pyrophosphorylase VC2762 [imported] -
Vibrio cholerae (group O1 strain N16961)
>gi|9657363|gb|AAF95901.1| (AE004342)
UDP-N-acetylglucosamine pyrophosphorylase [Vibrio
cholerae]
Length = 453
Score = 129 bits (320), Expect = 8e-29
Identities = 118/464 (25%), Positives = 203/464 (43%), Gaps = 88/464 (18%)
Query: 4 VVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPFVDEFI-IIVKYMKEKIIET 62
V+LAAGKG R+ + PK + +A KP+++++++ + + I ++ + +++ +
Sbjct: 6 VILAAGKGTRMH---SNMPKVLHTLAGKPMVKHVIDTCNNLGAQNIHLVYGHGGDQMQQA 62
Query: 63 LGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEE-FFAINGDI-YFEQEAIRGLLHVY 120
L +E + +V Q ++ GT A+ A + +++E + GD+ ++ I LL
Sbjct: 63 LANE----NVNWVLQAQQLGTGHAVDQASPHFQDDEKILVLYGDVPLISEDTIESLLEA- 117
Query: 121 KKTKANAALVVKKFDDLSQLGMVKTEGGYVREIVE-----------KPGNVGGLANLGIY 169
+ AL+ +D + G + + G V IVE K N G L G
Sbjct: 118 -QPTDGIALLTVVLEDPTGYGRIVRKRGPVVAIVEQKDASEEQKLIKEVNTGVLVATG-- 174
Query: 170 IFNPDVFEFIERTQESE-RGEYEITDTINLMISDGRKVAY------FEYSGFWSDI---- 218
D+ ++ + +GEY +TD I +GR V E G I
Sbjct: 175 ---RDLKRWLAGLNNNNAQGEYYLTDVIAAAHDEGRAVEAVHPSHSIEVEGVNDRIQLAR 231
Query: 219 ------GRPWDLLEVNEYILKTKLKHDIRGTVEEGA------------------------ 248
R L +L+ + D+RGT++ G+
Sbjct: 232 LERAFQARQAKKLLEQGVMLRDPARFDLRGTLQCGSDVEIDVNVIIEGNVSIGNNVVIGA 291
Query: 249 -TIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDNCHIGNAVEIKNS 307
+I+ EI + TV+R S I G +G+NC +GP +RP + D+ H+GN VE+KN+
Sbjct: 292 GSILKDCEIDDNTVIRPYSVIEGAT-VGENCTVGPFTRLRPGAELRDDAHVGNFVEMKNA 350
Query: 308 IIMDNSNAPHLNYVGDSIVGENTNLGAGTITANLRHDNRTIKVEIKGKLEDSGRRKLGAI 367
+ + S A HL Y+GD+ +G+ N+GAG IT N G K +
Sbjct: 351 RLGEGSKANHLTYLGDAEIGKGVNVGAGVITCNY-----------------DGANKHKTV 393
Query: 368 IGHNVKTGINVTIYPGRKIGSGALVGPGVIVDKNIPPNVLVVAK 411
IG +V G + + IG+GA +G G + KN+ LV+ +
Sbjct: 394 IGDDVFVGSDCQLVAPVTIGNGATIGAGTTLTKNVAEGELVITR 437
>pir||H81244 UDP-N-acetylglucosamine pyrophosphorylase NMB0038 [imported] -
Neisseria meningitidis (group B strain MD58)
>gi|7225258|gb|AAF40509.1| (AE002362)
UDP-N-acetylglucosamine pyrophosphorylase [Neisseria
meningitidis MC58]
Length = 456
Score = 129 bits (320), Expect = 8e-29
Identities = 121/471 (25%), Positives = 206/471 (43%), Gaps = 83/471 (17%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILEN---LDPFVDEFIIIVKYMKE 57
+ V+LAAGKG R+ PK + ++ KP++ +++ L+P +++ + KE
Sbjct: 6 LNIVILAAGKGTRMY---SKMPKVLHRIGGKPMVGRVIDTAAALNP--QNICVVIGHGKE 60
Query: 58 KIIETLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEE-EFFAINGDI-YFEQEAIRG 115
++++T+ + + +V Q E+ GT A+ +A ++ E + GD+ + E +
Sbjct: 61 QVLDTVK-----RDVVWVEQTEQLGTGHAVKTALPHLSAEGRTLVLYGDVPLIDVETLET 115
Query: 116 LLHVYKKTKANAALVVKKFDDLSQLG-MVKTEGGYVREIVE-KPGNVGGLA----NLGIY 169
LL L+ +D + LG +++ G V IVE K + A N GI
Sbjct: 116 LLEAAGN---EVGLLTDVPNDPTGLGRIIRDSNGSVTAIVEEKDADAVQKAVKEINTGIL 172
Query: 170 IF-NPDVFEFIER-TQESERGEYEITDTINLMISDGRKV--AYFEYSGFWSDIGRPWDLL 225
+ N + ++ + + +GEY +TD I ++DG KV S + + L
Sbjct: 173 VLPNAKLENWLNSLSSNNAQGEYYLTDLIAKAVADGIKVHPVQVRASHLAAGVNNKLQLT 232
Query: 226 EVNEYI--------------LKTKLKHDIRGTVEEGATII--------------PPVEIG 257
E+ L+ + D+RG ++ G ++ VEIG
Sbjct: 233 ELERIFQTEQAQELLKAGVTLRDPARFDLRGRLKHGQDVVIDVNCIFEGDIELGDNVEIG 292
Query: 258 EGTVVRSGSY----IIGPV------KIGKNCRIGPNCFIRPYTSIGDNCHIGNAVEIKNS 307
V+++ I P ++G+N RIGP +RP + D+ H+GN VEIKN+
Sbjct: 293 ANCVIKNAKIGANSKIAPFSHLESCEVGENNRIGPYARLRPQARLADDVHVGNFVEIKNA 352
Query: 308 IIMDNSNAPHLNYVGDSIVGENTNLGAGTITANLRHDNRTIKVEIKGKLEDSGRRKLGAI 367
I + A HL Y+GD+ VG TN GAGTI AN G K +
Sbjct: 353 AIGKGTKANHLTYIGDAEVGCKTNFGAGTIIANY-----------------DGVHKHKTV 395
Query: 368 IGHNVKTGINVTIYPGRKIGSGALVGPGVIVDKNIPPNVLVVAKQEKIVKE 418
IG V+ G N + +G+ G G + +N+ N L +A+ + V E
Sbjct: 396 IGDEVRIGSNCVLVAPVTLGNKVTTGAGSTITRNVEDNKLALARARQTVIE 446
>pir||T47698 mannose-1-phosphate guanylyltransferase-like protein - Arabidopsis
thaliana >gi|7076802|emb|CAB75917.1| (AL132975)
mannose-1-phosphate guanylyltransferase-like protein
[Arabidopsis thaliana]
Length = 364
Score = 128 bits (318), Expect = 1e-28
Identities = 101/353 (28%), Positives = 163/353 (45%), Gaps = 38/353 (10%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPF-VDEFIIIVKYMKEKI 59
MKA++L G G RLRPLT PKP++ ANKP+I + +E L VDE ++ + Y E++
Sbjct: 1 MKALILVGGFGTRLRPLTLSLPKPLVDFANKPMILHQIEALKAIGVDEVVLAINYEPEQL 60
Query: 60 I--ETLGDEFH---GKPITYVSQVEEEGTAKAIYSAKDYIEE---EEFFAINGDIYFEQE 111
+ ++ G IT + E GTA + A+D + + + FF +N D+ +
Sbjct: 61 LVMSKFSNDVEATLGIKITCSQETEPLGTAGPLALARDKLVDGSGQPFFVLNSDVISDYP 120
Query: 112 AIRGLLHVYKKTKANAALVVKKFDDLSQLGMVKTEG--GYVREIVEKPGN-VGGLANLGI 168
+ ++ + A+++V K D+ S+ G+V E G V VEKP VG N GI
Sbjct: 121 -LEEMIAFHNAHGGEASIMVTKVDEPSKYGVVVMEEATGRVERFVEKPKLFVGNKINAGI 179
Query: 169 YIFNPDVFEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVN 228
Y+ NP V + IE S I I I++ K+ GFW DIG+P D
Sbjct: 180 YLLNPSVLDRIELRPTS------IEKEIFPQIAEAEKLYAMLLPGFWMDIGQPRD----- 228
Query: 229 EYILKTKLKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRP 288
YI +L D + + + +G +I+G V + + IG C I P
Sbjct: 229 -YITGLRLYLD-------------SLRKKSPSKLATGPHILGNVLVDETAEIGEGCLIGP 274
Query: 289 YTSIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTITANL 341
+IG C + + V + + +M + + SI+G ++ +G N+
Sbjct: 275 NVAIGPGCVVESGVRLSHCTVMRGVHVKRYACISSSIIGWHSTVGQWARVENM 327
>pir||A70363 mannose-1-phosphate guanyltransferase - Aquifex aeolicus
>gi|2983302|gb|AAC06893.1| (AE000704)
mannose-1-phosphate guanyltransferase [Aquifex aeolicus]
Length = 831
Score = 127 bits (315), Expect = 3e-28
Identities = 93/340 (27%), Positives = 170/340 (49%), Gaps = 17/340 (5%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPFVDEFIIIVKYMKEKII 60
MK V+LA G G R++PLT+ PKP+L VAN+PI+E+++ L E I+++ Y + ++I
Sbjct: 1 MKGVILAGGFGTRIQPLTNSIPKPMLPVANRPIMEHVVHRLKEAGIEEIVVLLYYQAEVI 60
Query: 61 ETL---GDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLL 117
+ G +F G ITYV + GTA A+ A++Y+ E F ++GD+ + + L+
Sbjct: 61 KNYFKDGSDF-GVKITYVQPEADYGTAGAVKQAQNYL-NETFIIVSGDVITDFN-LSELI 117
Query: 118 HVYKKTKANAALVVKKFDDLSQLGMVKT-EGGYVREIVEKPG---NVGGLANLGIYIFNP 173
+K + L + ++ Q G+V T + G V + +EKPG N GIY+ P
Sbjct: 118 AFHKSKSSKFTLALYSVENPLQFGVVITNKEGKVLKFLEKPGWGEVFSDTVNTGIYVVEP 177
Query: 174 DVFEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILK 233
++ +I + + D ++ G + + G+W DIG +V++ I
Sbjct: 178 EILNYIPEDKPFDFA----MDLFPKLMKSGIDLWALKMRGYWRDIGNIDSYRDVHKDIFA 233
Query: 234 TKLKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIG 293
+K I G + T + + EGT + + G V +GKN ++G ++ IG
Sbjct: 234 GLVKIRIPGRII--TTKEARIYVEEGTEIPENVSLKGTVILGKNVKVGEGSELKNCV-IG 290
Query: 294 DNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLG 333
+N IG V++ +S++ N + + + + ++ + +G
Sbjct: 291 NNTVIGRNVKLFDSVLWWNVSIDEESEIRNGVICNDVKIG 330
>dbj|BAA77382.1| (AB020570) GDP-mannose pyrophosphorylase [Candida glabrata]
Length = 361
Score = 126 bits (314), Expect = 4e-28
Identities = 96/342 (28%), Positives = 163/342 (47%), Gaps = 35/342 (10%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENL-DPFVDEFIIIVKYMKEKI 59
MK ++L G G RLRPLT PKP+++ N+P+I + +E L + V + ++ V E +
Sbjct: 1 MKGLILVGGYGTRLRPLTLTVPKPLVEFGNRPMILHQIEALANAGVTDIVLAVNCRPEVM 60
Query: 60 IETLG--DEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEE--FFAINGDIYFEQEAIRG 115
+ETL ++ +G IT+ + E GTA + A+ ++++ FF +N D+ E +
Sbjct: 61 VETLQKYEKEYGVSITFSVETEPLGTAGPLKLAEKVLKKDNSPFFVLNSDVICEY-PFKE 119
Query: 116 LLHVYKKTKANAALVVKKFDDLSQLGMVKTE---GGYVREIVEKPGN-VGGLANLGIYIF 171
L +K +V K D+ S+ G++ + + VEKP VG N G+YI
Sbjct: 120 LADFHKAHGGKGTIVATKVDEPSKYGVIVHDIATPNLIDRFVEKPKEFVGNRINAGLYIL 179
Query: 172 NPDVFEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYI 231
NP+V + IE S T+T +++ + + + F+ GFW D+G+P D L
Sbjct: 180 NPEVIDLIEMKPTSIE-----TETFPILV-EQKSLYSFDLEGFWMDVGQPKDFLS----- 228
Query: 232 LKTKLKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTS 291
GTV + V + G I+G V + + +I + + P
Sbjct: 229 ----------GTV----LYLNSVSKKNPEKLTKGDNIVGNVMVDPSAKIAASAKVGPDVV 274
Query: 292 IGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLG 333
IG N IG V I S+++ +S+ + V +IVG + +G
Sbjct: 275 IGPNVTIGEGVRITRSVVLSDSSIQDHSLVKSTIVGWKSTVG 316
>pir||S76009 hypothetical protein - Synechocystis sp. (strain PCC 6803)
>gi|1001368|dbj|BAA10856.1| (D64006)
UDP-N-acetylglucosamine pyrophosphorylase [Synechocystis
sp.]
Length = 456
Score = 125 bits (312), Expect = 7e-28
Identities = 126/467 (26%), Positives = 199/467 (41%), Gaps = 96/467 (20%)
Query: 5 VLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPFVDEF-IIIVKYMKEKIIETL 63
VLAAGKG R++ D PK + ++ ++E +L++ P E I+IV Y + +L
Sbjct: 6 VLAAGKGTRMK---SDLPKVLHQLGGYSLVERVLQSCRPLAPERQILIVGYQAAAVESSL 62
Query: 64 GDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEE--FFAINGDI-YFEQEAIRGLLHVY 120
+ +V Q E+ GT AI +++ + +NGD E + LL +
Sbjct: 63 AGR---SDVEFVEQREQLGTGHAIQQLLPCLQDYQGDLLVLNGDAPLLRSETLENLLATH 119
Query: 121 KKTKANAALVVKKFDDLSQLGMVKTEG-GYVREIVEKPG-----NVGGLANLGIYIFN-P 173
++ A L+ D G V G V +IVE N GIY F+ P
Sbjct: 120 QRHGNAATLLTAHLPDPKGYGRVFCNGDNRVTQIVEDRDCNAAQRQNHRVNGGIYCFHWP 179
Query: 174 DVFEFIER-TQESERGEYEITDTINLM-------ISDGRKVAYFEYSGFWSDIGRPWDLL 225
+ + + + +++ EY +T+ ++ + + D Y E +G I L
Sbjct: 180 RLAAALPKLSANNDQKEYYLTEVVDYLDQVMAVDVDD-----YLEING----INDRKQLA 230
Query: 226 EVNEYILKTKLKHDIRGTVEEGATIIPPVEIG-EGTVVRSGSYIIGP-------VKIGKN 277
N+ IL+ ++K D + +G T+I P I + TVV II P IG+
Sbjct: 231 AAND-ILQNRIKDD---WMAQGITLINPDSITIDDTVVLEADVIIEPNTHLRGKTVIGRG 286
Query: 278 CRIGP---------------------------NCFIRPYT------SIGDNCHIGNAVEI 304
RIGP C + PY+ I NC IGN VE+
Sbjct: 287 SRIGPGSLIEDSIVGSDASVLFSVVSQSQIGDGCRLGPYSHVRGEADIQANCRIGNFVEV 346
Query: 305 KNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTITANLRHDNRTIKVEIKGKLEDSGRRKL 364
K S+I SN HL+Y+GD+++G+ N+GAGTITAN G K
Sbjct: 347 KKSVIGAQSNVAHLSYLGDAMLGQRVNVGAGTITANY-----------------DGVSKH 389
Query: 365 GAIIGHNVKTGINVTIYPGRKIGSGALVGPGVIVDKNIPPNVLVVAK 411
+IG KTG N ++G G V G ++++++P L +A+
Sbjct: 390 ATVIGSGTKTGANSVFVAPVQVGEGVTVAAGSVINRDVPAGSLAIAR 436
>pir||G82023 UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.23) NMA0284
[imported] - Neisseria meningitidis (group A strain
Z2491) >gi|7379045|emb|CAB83591.1| (AL162752)
UDP-N-acetylglucosamine pyrophosphorylase [Neisseria
meningitidis Z2491]
Length = 456
Score = 125 bits (310), Expect = 1e-27
Identities = 118/470 (25%), Positives = 202/470 (42%), Gaps = 85/470 (18%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILEN---LDPFVDEFIIIVKYMKE 57
+ V+LAAGKG R+ PK + ++ + ++ +++ L+P ++V + KE
Sbjct: 6 LNIVILAAGKGTRMY---SKMPKVLHEIGGETMLGRVIDTAAALNP--QNICVVVGHGKE 60
Query: 58 KIIETLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEE-EFFAINGDI-YFEQEAIRG 115
++++T+ + + +V Q E+ GT A+ +A ++ E + GD+ + E +
Sbjct: 61 QVLDTVK-----RDVVWVEQTEQLGTGHAVKTALPHLAAEGRTLVLYGDVPLIDVETLET 115
Query: 116 LLHVYKKTKANAALVVKKFDDLSQLG-MVKTEGGYVREIVE-KPGNVGGLA----NLGIY 169
LL L+ D S LG +++ G V IVE K + A N GI
Sbjct: 116 LLEAAGN---EVGLLTDVPADPSGLGRIIRDSSGSVTAIVEEKDADAAQKAVKEINTGIL 172
Query: 170 IFNPDVFE--FIERTQESERGEYEITDTINLMISDGRKV--AYFEYSGFWSDIGRPWDLL 225
+ E + + +GEY +TD I ++DG K+ S + + L
Sbjct: 173 VLPNAKLEAWLNSLSSNNAQGEYYLTDLIAKAVADGIKIHPVQVRSSHLAAGVNNKLQLA 232
Query: 226 EVNEYI--------------LKTKLKHDIRGTVEEGATII--------------PPVEIG 257
E+ L+ + D+RG ++ G ++ VEIG
Sbjct: 233 ELERIFQTEQAQELLKAGVTLRDPARFDLRGRLKHGQDVVIDVNCIFEGKIELGDNVEIG 292
Query: 258 EGTVVRSG-----------SYIIGPVKIGKNCRIGPNCFIRPYTSIGDNCHIGNAVEIKN 306
V+++ S++ G ++G+N +IGP +RP + D+ H+GN VEIKN
Sbjct: 293 ANCVIKNAKIGANSKIAPFSHLEG-CEVGENNQIGPYARLRPQAKLADDVHVGNFVEIKN 351
Query: 307 SIIMDNSNAPHLNYVGDSIVGENTNLGAGTITANLRHDNRTIKVEIKGKLEDSGRRKLGA 366
+ I + A HL Y+GD+ VG TN GAGTI AN G K
Sbjct: 352 AAIGKGTKANHLTYIGDAEVGSKTNFGAGTIIANY-----------------DGVHKHKT 394
Query: 367 IIGHNVKTGINVTIYPGRKIGSGALVGPGVIVDKNIPPNVLVVAKQEKIV 416
+IG V+ G N + KIG+ G G + +N+ L +A+ + +
Sbjct: 395 VIGDEVRIGSNCVLVSPVKIGNKVTTGAGSTITRNVEDGKLALARSRQTI 444
>gb|AAF52089.1| (AE003605) CG1129 gene product [alt 1] [Drosophila melanogaster]
>gi|10727176|gb|AAG22216.1| (AE003605) CG1129 gene
product [alt 2] [Drosophila melanogaster]
Length = 369
Score = 125 bits (310), Expect = 1e-27
Identities = 108/343 (31%), Positives = 161/343 (46%), Gaps = 41/343 (11%)
Query: 2 KAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENL-DPFVDEFIIIVKYMKEKII 60
+A++L G G RLRPLT PKP+++ ANKPI+ + LE L D + I+ V Y E++
Sbjct: 12 RALILVGGYGTRLRPLTLSTPKPLVEFANKPILLHQLEALVDAGCRQVILAVSYRAEQME 71
Query: 61 ETLGDEFH--GKPITYVSQVEEEGTAKAIYSAKDYI--EEEEFFAINGDIYFEQEAIRGL 116
+ L E G + + + E GTA + AK + E FF +N D+ + + L
Sbjct: 72 KELKVEAKKLGVELIFSHETEPLGTAGPLALAKTILAASSEPFFVLNSDVICD-FPFKQL 130
Query: 117 LHVYKKTKANAALVVKKFDDLSQLGMV-KTEGGYVREIVEKPGN-VGGLANLGIYIFNPD 174
+ + +VV K ++ S+ G+V E G ++ +EKP V N GIYIFNP
Sbjct: 131 VQFHCNHGKEGTIVVTKVEEPSKYGVVLYDENGCIKNFIEKPQEFVSNKINAGIYIFNPS 190
Query: 175 VFEFIERTQESERGEY--EITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLE-VNEYI 231
V + IE S E E+T L D +GFW DIG+P D L + Y+
Sbjct: 191 VLDRIEVKPTSIEKEVFPEMTQQQELYAMD--------LTGFWMDIGQPKDFLTGMCLYL 242
Query: 232 LKTKLKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGP-VKIGKNCRIGPNCFIRPYT 290
+ K P + G G V G+ ++ P KIG+ CRIGPN I P
Sbjct: 243 SSLRQKQS------------PKLYTGPGVV---GNVLVDPTAKIGEGCRIGPNVTIGPDV 287
Query: 291 SIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLG 333
I D I + +K +I+ +S ++ IVG + +G
Sbjct: 288 VIEDGVCIKRSTILKGAIVRSHS------WLDSCIVGWRSTVG 324
>pir||G81500 UDP-N-acetlyglucosamine pyrophosphorylase GlmU-related enzyme
CP1124 [imported] - Chlamydophila pneumoniae (strain
AR39) >gi|7190036|gb|AAF38890.1| (AE002268)
UDP-N-acetlyglucosamine pyrophosphorylase GlmU-related
enzyme [Chlamydophila pneumoniae AR39]
Length = 176
Score = 123 bits (306), Expect = 3e-27
Identities = 68/175 (38%), Positives = 94/175 (52%), Gaps = 5/175 (2%)
Query: 229 EYILKTKLKHDIRGTVEEGATI--IPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFI 286
+ +L+ + I GTVE G T+ I +EI E V SG+YI+GP +G + ++
Sbjct: 2 DQMLENHVFSGIHGTVESGVTLKNIEKIEIAEDAYVESGAYIVGPCILGSQTEVRHGAYL 61
Query: 287 RPYTSIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTITANLRHDNR 346
R G C +G+ EIKNS + ++ A H Y+GDS++ NLGAG AN R D R
Sbjct: 62 RGNVITGSRCVVGHCTEIKNSYLGHHTKAAHFAYLGDSVLSSEVNLGAGVRCANFRLDGR 121
Query: 347 TIKVEI---KGKLEDSGRRKLGAIIGHNVKTGINVTIYPGRKIGSGALVGPGVIV 398
I V K K D+GRRKLGA +G V G NV I PG+ I + PG ++
Sbjct: 122 NIYVRSTSDKSKKIDTGRRKLGAFLGKGVAIGCNVVINPGQHILPHTRIRPGQVI 176
>pir||T32900 hypothetical protein C42C1.5 - Caenorhabditis elegans
>gi|2804432|gb|AAB97547.1| (AF043695) similar to S.
cerevisiae mannose-1-phosphate guanyltransferase
(GB:U24437) [Caenorhabditis elegans]
Length = 373
Score = 122 bits (304), Expect = 6e-27
Identities = 101/352 (28%), Positives = 166/352 (46%), Gaps = 35/352 (9%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENL-DPFVDEFIIIVKYMKEKI 59
MKA++L G G RLRPLT +PKP+++ ANKP++ + +E L + VD ++ V Y E++
Sbjct: 9 MKALILVGGYGTRLRPLTLTQPKPLVEFANKPMMLHQMEALAEVGVDTVVLAVSYRAEQL 68
Query: 60 IETLGDEFHGKPITYVSQVEEE--GTAKAIYSAKDYIE-EEEFFAINGDIYFEQEAIRGL 116
+ + + + +EEE GTA + A+ ++E + FF +N D+ + + +
Sbjct: 69 EQEMTVHADRLGVKLIFSLEEEPLGTAGPLALARKHLEGDAPFFVLNSDVICD-FPFKQM 127
Query: 117 LHVYKKTKANAALVVKKFDDLSQLGMV--KTEGGYVREIVEKPGN-VGGLANLGIYIFNP 173
+ +K + V K ++ S+ G+V + G + + VEKP VG N G+YIF+
Sbjct: 128 VEFHKNHGKEGTIAVTKVEEPSKYGVVVFDQDKGKIDDFVEKPQEYVGNKINAGLYIFSS 187
Query: 174 DVFEFIERTQESERGEY--EITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYI 231
+ + I S E E+ + NL F GFW D+G+P D L+
Sbjct: 188 KILDRIPLKPTSIEKEIFPEMAFSGNLYA--------FVLPGFWMDVGQPKDFLKGMSLF 239
Query: 232 LK--TKLKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPY 289
L K D +E G+ I P I G V + + +G NC I P
Sbjct: 240 LNHCHTTKSD---KLETGSNIHPTATIR------------GNVMVDPSATVGENCVIGPD 284
Query: 290 TSIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTITANL 341
IG I V I +S I+ +S+ + ++V SIVG ++G+ N+
Sbjct: 285 VVIGPRVKIEGGVRILHSTILSDSSIGNYSWVSGSIVGRKCHIGSWVRIENI 336
>gb|AAG18686.1| (AE004973) glucose-1-phosphate thymidylyltransferase; GraD6
[Halobacterium sp. NRC-1]
Length = 218
Score = 122 bits (303), Expect = 8e-27
Identities = 74/216 (34%), Positives = 123/216 (56%), Gaps = 7/216 (3%)
Query: 25 ILKVANKPIIEYILENLDPF-VDEFIIIVKYMKEKIIETLGDEFHGKPITYVSQVEEEGT 83
+++V KPI+ + E L D +++V Y K+ IIE GDEF G PITY Q E++G
Sbjct: 1 MVEVDGKPILTHCFEQLVELGADGLVVVVGYRKQDIIEHYGDEFEGVPITYAHQREQKGL 60
Query: 84 AKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLLHVYKKTKANAALVVKK--FDDLSQLG 141
A A+ + ++++ +E+F + GD F Q + ++ ++ +A+AA +V++ +DD S+ G
Sbjct: 61 AHALLNVEEHV-DEDFMLMLGDNIF-QANLEDVVRRQQEERADAAFLVEEVDWDDASRYG 118
Query: 142 MVKT-EGGYVREIVEKPGN-VGGLANLGIYIFNPDVFEFIERTQESERGEYEITDTINLM 199
+ T + G V ++VEKP + L G Y F+P +F Q S RGEYEI++ I+L+
Sbjct: 119 VCDTNQYGEVTDVVEKPDDPPSNLVMTGFYTFSPAIFHACHLVQPSNRGEYEISEAIDLL 178
Query: 200 ISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKTK 235
I GR + G+ D+G P D E E + + +
Sbjct: 179 IQSGRTIDAIGLEGWRVDVGYPEDREEAEERLAEAE 214
>gb|AAG18702.1| (AE004975) glucose-1-phosphate thymidylyltransferase; GraD3
[Halobacterium sp. NRC-1]
Length = 238
Score = 122 bits (302), Expect = 1e-26
Identities = 78/239 (32%), Positives = 122/239 (50%), Gaps = 13/239 (5%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILE-NLDPFVDEFIIIVKYMKEKI 59
MKAVVLAAG+G RLRP T D PKP+++V KPI+ + E LD +D+ +++V Y K+KI
Sbjct: 1 MKAVVLAAGEGTRLRPRTADLPKPLVEVNGKPILTHCFEILLDLGIDDVVVVVGYEKDKI 60
Query: 60 IETLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLLHV 119
I+ GD F I Y Q E G A A+ +A+ Y+ + +F +NGD + L H
Sbjct: 61 IDRYGDSFRAIDIEYAHQSERLGLAHAVLTAEPYV-DSDFVVLNGDNIYSANFSEVLAH- 118
Query: 120 YKKTKANAALVVKKFDD-------LSQLGMVKTEGGYVREIVEKPGNVGGLANLGIYIFN 172
+ ++ A+ V++ + +L + G V + E P N A Y+
Sbjct: 119 HTESGADITFPVEEVSTEEATSGAVCELDDDRAVTGLVEKPAEPPSN---YAPTAFYVLP 175
Query: 173 PDVFEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYI 231
P +F + SERGEYE+ D I+L+I G V + G+ ++ D+ + +
Sbjct: 176 PAIFPACRVIRPSERGEYELADAIDLLIYSGYSVETQPFEGWKVNVNTEADITRAEQLL 234
>pir||E70622 probable udp-n-acetylglucosamine pyrophosphorylase - Mycobacterium
tuberculosis (strain H37RV) >gi|1870010|emb|CAB06861.1|
(Z92539) glmU [Mycobacterium tuberculosis]
Length = 495
Score = 121 bits (300), Expect = 2e-26
Identities = 111/461 (24%), Positives = 196/461 (42%), Gaps = 74/461 (16%)
Query: 4 VVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPFVDE-FIIIVKYMKEKIIET 62
+VLAAG G R+R D PK + +A + ++ ++L + + I+++ + ++I
Sbjct: 10 LVLAAGPGTRMR---SDTPKVLHTLAGRSMLSHVLHAIAKLAPQRLIVVLGHDHQRIAPL 66
Query: 63 LGD--EFHGKPITYVSQVEEEGTAKAIYSAKDYIEEE---EFFAINGDI-YFEQEAIRGL 116
+G+ + G+ I Q GT A+ + ++ +GD + + + L
Sbjct: 67 VGELADTLGRTIDVALQDRPLGTGHAVLCGLSALPDDYAGNVVVTSGDTPLLDADTLADL 126
Query: 117 LHVYKKTKANAALVVKKFDDLSQLGMV-KTEGGYVREIVEKPGNVGGL-----ANLGIYI 170
+ ++ A ++ DD G + +T+ V IVE+ N G+Y
Sbjct: 127 IATHRAVSAAVTVLTTTLDDPFGYGRILRTQDHEVMAIVEQTDATPSQREIREVNAGVYA 186
Query: 171 FNPDVFEFIERTQESERGEYEI--TDTINLMISDGRKV--AYFEYSGFWSDIGRPWDLLE 226
F+ S + E+ TD I ++ SDG+ V ++ + S + + L E
Sbjct: 187 FDIAALRSALSRLSSNNAQQELYLTDVIAILRSDGQTVHASHVDDSALVAGVNNRVQLAE 246
Query: 227 V-NEYILKTKLKHDIRG-TVEEGAT--IIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGP 282
+ +E + H + G TV + AT I V IG TV+ G+ ++G +IG C +GP
Sbjct: 247 LASELNRRVVAAHQLAGVTVVDPATTWIDVDVTIGRDTVIHPGTQLLGRTQIGGRCVVGP 306
Query: 283 NC---------------------------------FIRPYTSIGDNCHIGNAVEIKNSII 309
+ ++RP T++G + +G VE+KNS I
Sbjct: 307 DTTLTDVAVGDGASVVRTHGSSSSIGDGAAVGPFTYLRPGTALGADGKLGAFVEVKNSTI 366
Query: 310 MDNSNAPHLNYVGDSIVGENTNLGAGTITANLRHDNRTIKVEIKGKLEDSGRRKLGAIIG 369
+ PHL YVGD+ +GE +N+GA ++ N G K +G
Sbjct: 367 GTGTKVPHLTYVGDADIGEYSNIGASSVFVNY-----------------DGTSKRRTTVG 409
Query: 370 HNVKTGINVTIYPGRKIGSGALVGPGVIVDKNIPPNVLVVA 410
+V+TG + IG GA G G +V +++PP L V+
Sbjct: 410 SHVRTGSDTMFVAPVTIGDGAYTGAGTVVREDVPPGALAVS 450
>pir||A82952 glucosamine-1-phosphate acetyltransferase/
N-acetylglucosamine-1-phosphate uridyltransferase PA5552
[imported] - Pseudomonas aeruginosa (strain PAO1)
>gi|9951892|gb|AAG08937.1|AE004967_8 (AE004967)
glucosamine-1-phosphate
acetyltransferase/N-acetylglucosamine-1-phosphate
uridyltransferase [Pseudomonas aeruginosa]
Length = 454
Score = 121 bits (300), Expect = 2e-26
Identities = 113/469 (24%), Positives = 197/469 (41%), Gaps = 92/469 (19%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPFVDEFI-IIVKYMKEKI 59
++ V+LAAG+G R+R PK + +A KP++ ++++ E I +++ + + +
Sbjct: 3 LEIVILAAGQGTRMRSAL---PKVLHPIAGKPMLGHVIDCARQLQPERIHVVIGHGADLV 59
Query: 60 IETLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLLHV 119
E + + + +V Q E+ GT A+ A ++ ++ + GD+ Q L
Sbjct: 60 RERMAAD----DLNFVLQAEQLGTGHAVAQALPFLSADQVLILYGDVPLIQLDTLQRLLA 115
Query: 120 YKKTKANAALVVKKFDDLSQLGMVKTEGGYVREIVEKPGNVGGLANLG------IYIFNP 173
+ L V D +V+ + G V+ IVE +G + +
Sbjct: 116 QVTPDQLSLLTVDMLDPTGYGRIVRDDQGAVQAIVEHKDATPAQRQIGEINTGILAVPGK 175
Query: 174 DVFEFIER-TQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEV---NE 229
+ +++ R + ++ +GEY +TD I + + DG VA +P D +EV N+
Sbjct: 176 RLADWLGRLSNDNAQGEYYLTDVIAMAVGDGLVVAS----------AQPLDAMEVQGVND 225
Query: 230 YILKTKL-KHDIRGTVEE----GATIIPP--------VEIGEGTVVRSGSYIIGPVKIGK 276
+ + +L +H R EE G T++ P + +G ++ + G V I
Sbjct: 226 RMQQAQLERHYQRLRAEELMRQGVTLLDPQRLDVRGEISVGRDVLIDVNVVLEGRVVIED 285
Query: 277 NCRIGPNCFIR----------------------------------PYTSIGDNCHIGNAV 302
+ RIGPNC IR P + +G H+GN V
Sbjct: 286 DVRIGPNCVIRDSVLRRGAVIKANSHLEGAELGEGSDAGPFARLRPGSVLGARAHVGNFV 345
Query: 303 EIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTITANLRHDNRTIKVEIKGKLEDSGRR 362
E+KN+ + + S A HL+Y+GD+ +G N N+GAGTIT N G
Sbjct: 346 ELKNARLGEGSKAGHLSYLGDAELGANCNIGAGTITCNY-----------------DGAN 388
Query: 363 KLGAIIGHNVKTGINVTIYPGRKIGSGALVGPGVIVDKNIPPNVLVVAK 411
K +G +V G N ++ KIG GA G + +P L +
Sbjct: 389 KFRTELGDDVFIGSNNSLVAPLKIGDGATTAAGSTITHEVPAKNLAFGR 437
>gb|AAK40709.1| Sugar phosphate nucleotydyl transferase [Sulfolobus solfataricus]
Length = 363
Score = 117 bits (290), Expect = 3e-25
Identities = 104/344 (30%), Positives = 158/344 (45%), Gaps = 24/344 (6%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPF-VDEFIIIVKYMKEKI 59
MKA+VLA GKGE L P T+ K + V K II Y +E L V EF IIV +I
Sbjct: 4 MKAIVLAGGKGEGLLPYTEKVQKEAITVLGKAIINYTIEGLKKAGVKEFEIIVNEKGNQI 63
Query: 60 IETLGDEFHGKPITYVSQVEE-EGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLLH 118
E E +++ + V++ +G A+ + I+++ F GDI E + L+
Sbjct: 64 EE----EVEKLDVSFETIVQKKQGIDGAVLEGIESIDDDVFVLAFGDIIAPAEFYKSLMD 119
Query: 119 VYKKTKANAAL-VVKKFDDLSQLGMVKTEGGYVREIVEKPGNVGGLANLGIYIFNPDVFE 177
Y T + A + ++ + G+VK ++ + E LA G YI
Sbjct: 120 TYIMTGSQAVIPLIPISEGTETYGLVKIVDNKLKVVKES----STLALGGAYILPKPKDN 175
Query: 178 FIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKTKLK 237
F + D I+L+ S R + YF +S W DIG P DLL E +L+ K
Sbjct: 176 FTS-----------LLDYIDLLSSQAR-LNYFIWSESWVDIGYPEDLLFALETLLRRKES 223
Query: 238 H-DIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDNC 296
+ + + A I V I + ++ + I GP IGKN +G +R Y+SI +
Sbjct: 224 VISDKAEISKNAIIGKGVIIEDYAIIEDYAIIKGPAYIGKNAYVGSFSLVRDYSSIEEGA 283
Query: 297 HIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTITAN 340
IG EI +S+I + +Y+ SIVG+ +GA ITA+
Sbjct: 284 KIGAYCEIAHSLIEPFAEVGSKSYLTYSIVGKGAKIGASVITAS 327
>pir||C64605 UDP-N-acetylglucosamine pyrophosphorylase - Helicobacter pylori
(strain 26695) >gi|2313807|gb|AAD14885.1| (AE000581)
UDP-N-acetylglucosamine pyrophosphorylase (glmU)
[Helicobacter pylori 26695]
Length = 433
Score = 116 bits (288), Expect = 5e-25
Identities = 123/445 (27%), Positives = 196/445 (43%), Gaps = 64/445 (14%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPFVDEFIIIVKYMKEKII 60
+ ++LAAGKG R+R PK + + +P++ YILE D+ +I+ + +E+I
Sbjct: 2 LSVIILAAGKGTRMR---SSLPKTLHTICGEPMLFYILETAFSISDDVHLILHHQQERIK 58
Query: 61 ETLGDEFHGKPITYVSQVEEE--GTAKAIYSAKD----YIEEEEFFAINGDI-YFEQEAI 113
E + + F G + + +Q+ E+ GT AI KD + E +N D+ ++A+
Sbjct: 59 EAVLERFKG--VIFHTQIVEKYSGTGGAIMQ-KDKTPISTKHERVLILNADMPLITKDAL 115
Query: 114 RGLLHVYKKTKANAALVVKKFDDLSQLGMVKTEGGYVREIV-EKPGNVG----GLANLGI 168
LL N A+ + D G V E V++IV EK N N G+
Sbjct: 116 APLLE-----SKNNAIGLLHLADPKGYGRVVLENHQVKKIVEEKDANDEEKEIKSVNAGV 170
Query: 169 YIFNPDVFE--FIERTQESERGEYEITDTINLMISDGRKV-AYFEYSGFWSDIGRPWDLL 225
Y F D E + ++ + EY +TD I L I++ + A F + + +
Sbjct: 171 YGFERDFLEKYLPKLHDQNAQKEYYLTDLIALGINENETIDAIFLKEECFLGVNSQTERA 230
Query: 226 EVNEYILKTKLKHDI-RGTVEEGATII---PPVEIGEGTVVRSGSYIIGPVKIGK----- 276
+ E +L+ K+ + G V + I V V+ G +IG I
Sbjct: 231 KAEEIMLERLRKNAMDLGVVMQLPNSIYLEKGVSFKGECVLEQGVRLIGNCLIENAHIKA 290
Query: 277 ----------NCRIGPNCFIRPYTSIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIV 326
N +GP RP S+ N H+GN VE KN+ + + A HL+Y+GD +
Sbjct: 291 YSVIEESQIVNSSVGPFAHARP-KSVICNSHVGNFVETKNA-KLQGTKAGHLSYLGDCEI 348
Query: 327 GENTNLGAGTITANLRHDNRTIKVEIKGKLEDSGRRKLGAIIGHNVKTGINVTIYPGRKI 386
G+NTN+GAG IT N G++K IIG NV G + + I
Sbjct: 349 GKNTNVGAGVITCNY-----------------DGKKKHQTIIGENVFIGSDSQLVAPINI 391
Query: 387 GSGALVGPGVIVDKNIPPNVLVVAK 411
GS L+G G + K+IP L +++
Sbjct: 392 GSNVLIGSGTTITKDIPSGSLSLSR 416
>pir||F81276 probable sugar-phosphate nucleotide transferase Cj1329 [imported] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6968763|emb|CAB73756.1| (AL139078) putative
sugar-phosphate nucleotide transferase [Campylobacter
jejuni]
Length = 341
Score = 115 bits (284), Expect = 1e-24
Identities = 77/230 (33%), Positives = 127/230 (54%), Gaps = 15/230 (6%)
Query: 4 VVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENL-DPFVDEFIIIVKYMKEKIIET 62
+++A G G RL+ LT D PKP+LKV KPI+E I++ L + + FI V Y K++IIE
Sbjct: 120 IIMAGGLGSRLKELTKDTPKPMLKVGKKPILESIIQRLKNQNFENFIFCVNY-KKQIIED 178
Query: 63 L---GDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLLHV 119
G +F G I+Y+ + ++ GTA A+ K +E F +N DI E + LL
Sbjct: 179 YFQKGQKF-GVKISYIKERKKLGTAGALSLIKQEF-KESFIVMNADILTELD-FNALLKA 235
Query: 120 YKKTKANAALVVKKFDDLSQLGMVKTEGGYVREIVEKPGNVGGLANLGIYIFNPDVFEFI 179
+KK+KA ++ V++F+ G++ + G++ I EKP L + GIY+ ++ I
Sbjct: 236 HKKSKALMSVCVREFEQQIPYGVITQKQGFIENIEEKP-TQKFLVSAGIYVLENEILNLI 294
Query: 180 ERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNE 229
+ + ++ + I L++ G KV + + +W DIGRP + L+ NE
Sbjct: 295 AKNE-----YLDMPELIKLVLQKG-KVNTYIINDYWIDIGRPDEFLKANE 338
>gi|11431484 GDP-mannose pyrophosphorylase B [Homo sapiens]
Length = 360
Score = 114 bits (283), Expect = 2e-24
Identities = 97/342 (28%), Positives = 158/342 (45%), Gaps = 36/342 (10%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPF-VDEFIIIVKYMKEKI 59
MKA++L G G RLRPLT PKP++ NKPI+ + +E L VD I+ V YM + +
Sbjct: 1 MKALILVGGYGTRLRPLTLSTPKPLVDFCNKPILLHQVEALAAAGVDHVILAVSYMSQVL 60
Query: 60 IETLGDEFHGKPITYVSQVEEE--GTAKAIYSAKDYIEE--EEFFAINGDIYFEQEAIRG 115
+ + + I EEE GTA + A+D + E + FF +N D+ + +
Sbjct: 61 EKEMKAQEQRLGIRISMSHEEEPLGTAGPLALARDLLSETADPFFVLNSDVICD-FPFQA 119
Query: 116 LLHVYKKTKANAALVVKKFDDLSQLGMVKTEG--GYVREIVEKPG-NVGGLANLGIYIFN 172
++ ++ +++V K ++ S+ G+V E G + VEKP V N G+YI +
Sbjct: 120 MVQFHRHHGQEGSILVTKVEEPSKYGVVVCEADTGRIHRFVEKPQVFVSNKINAGMYILS 179
Query: 173 PDVFEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLE-VNEYI 231
P V + I+ S E +M +G+ A E GFW DIG+P D L + ++
Sbjct: 180 PAVLQRIQLQPTSIEKE-----VFPIMAKEGQLYA-MELQGFWMDIGQPKDFLTGMCLFL 233
Query: 232 LKTKLKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTS 291
+ K R + SG I+G V + + RIG NC I P S
Sbjct: 234 QSLRQKQPER--------------------LCSGPGIVGNVLVDPSARIGQNCSIGPNVS 273
Query: 292 IGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLG 333
+G + + V I+ ++ ++ +++ IVG +G
Sbjct: 274 LGPGVVVEDGVCIRRCTVLRDARIRSHSWLESCIVGWRCRVG 315
>pir||A71909 udp-n-acetylglucosamine pyrophosphorylase - Helicobacter pylori
(strain J99) >gi|4155177|gb|AAD06204.1| (AE001494)
UDP-N-ACETYLGLUCOSAMINE PYROPHOSPHORYLASE [Helicobacter
pylori J99]
Length = 433
Score = 114 bits (282), Expect = 2e-24
Identities = 117/447 (26%), Positives = 196/447 (43%), Gaps = 68/447 (15%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPFVDEFIIIVKYMKEKII 60
+ ++LAAGKG R+ PK + + +P++ YILE ++ +++ + +E+I
Sbjct: 2 LSVIILAAGKGTRMH---SSLPKTLHTICGEPMLFYILEVAFSISNDVHLVLHHQQERIK 58
Query: 61 ETLGDEFHGKPITYVSQVEEE--GTAKAIYSAKDY---IEEEEFFAINGDI-YFEQEAIR 114
E + F G + + +Q+ E+ GT AI + E +N D+ ++A+
Sbjct: 59 EAVSKRFKG--VIFHAQIVEKYSGTGGAIMQENKTPIPTQHERVLILNADMPLITKDALT 116
Query: 115 GLLHVYKKTKANAALVVKKFDDLSQLGMVKTEGGYVREIVEKPG-----NVGGLANLGIY 169
LL + N A+ + D G V E V++IVE+ N G+Y
Sbjct: 117 PLLESH-----NNAIGLLHLADPKGYGRVILENHQVKKIVEEKDANDEEKTIKSVNAGVY 171
Query: 170 IFNPDVFEFIER-----TQESERGEYEITDTINLMISDGRKV-AYFEYSGFWSDIGRPWD 223
F +F+ER ++ + EY +TD I L I K+ A F + + +
Sbjct: 172 FFER---KFLERYLPKLHDQNAQKEYYLTDLIALGIKGNEKIDAIFLEEECFLGVNSQTE 228
Query: 224 LLEVNEYILKTKLKH--DIRGTVEEGATII--PPVEIGEGTVVRSGSYIIGPVKIGK--- 276
+ E +L+ K+ D+ ++ ++I V V+ G +IG I
Sbjct: 229 RAKAEEIMLERLRKNAMDLGVVMQLPSSIYLEKGVSFKGECVLEQGVRLIGNCLIENARI 288
Query: 277 ------------NCRIGPNCFIRPYTSIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDS 324
N +GP RP + I D+ H+GN VE KN+ + + A HL+Y+GD
Sbjct: 289 KAYSVIEESQIINSSVGPFAHARPKSVICDS-HVGNFVETKNA-KLQGTKAGHLSYLGDC 346
Query: 325 IVGENTNLGAGTITANLRHDNRTIKVEIKGKLEDSGRRKLGAIIGHNVKTGINVTIYPGR 384
+G+NTN+GAG IT N G++K IIG NV G + +
Sbjct: 347 EIGKNTNVGAGVITCNY-----------------DGKKKHQTIIGENVFIGSDSQLVAPI 389
Query: 385 KIGSGALVGPGVIVDKNIPPNVLVVAK 411
IGS L+G G + K+IP L +++
Sbjct: 390 NIGSNVLIGSGTTITKDIPSGSLSLSR 416
>gi|7019397 GDP-mannose pyrophosphorylase B [Homo sapiens]
>gi|5052351|gb|AAD38516.1|AF135421_1 (AF135421)
GDP-mannose pyrophosphorylase B [Homo sapiens]
Length = 360
Score = 113 bits (281), Expect = 3e-24
Identities = 97/342 (28%), Positives = 157/342 (45%), Gaps = 36/342 (10%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPF-VDEFIIIVKYMKEKI 59
MKA++L G G RLRPLT PKP++ NKPI+ + +E L VD I+ V YM + +
Sbjct: 1 MKALILVGGYGTRLRPLTLSTPKPLVDFCNKPILLHQVEALAAAGVDHVILAVSYMSQVL 60
Query: 60 IETLGDEFHGKPITYVSQVEEE--GTAKAIYSAKDYIEE--EEFFAINGDIYFEQEAIRG 115
+ + + I EEE GTA + A+D + E + FF +N D+ + +
Sbjct: 61 EKEMKAQEQRLGIRISMSHEEEPLGTAGPLALARDLLSETADPFFVLNSDVICD-FPFQA 119
Query: 116 LLHVYKKTKANAALVVKKFDDLSQLGMVKTEG--GYVREIVEKPG-NVGGLANLGIYIFN 172
++ ++ +++V K ++ S+ G+V E G + VEKP V N G+YI +
Sbjct: 120 MVQFHRHHGQEGSILVTKVEEPSKYGVVVCEADTGRIHRFVEKPQVFVSNKINAGMYILS 179
Query: 173 PDVFEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLE-VNEYI 231
P V I+ S E +M +G+ A E GFW DIG+P D L + ++
Sbjct: 180 PAVLRRIQLQPTSIEKE-----VFPIMAKEGQLYA-MELQGFWMDIGQPKDFLTGMCLFL 233
Query: 232 LKTKLKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTS 291
+ K R + SG I+G V + + RIG NC I P S
Sbjct: 234 QSLRQKQPER--------------------LCSGPGIVGNVLVDPSARIGQNCSIGPNVS 273
Query: 292 IGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLG 333
+G + + V I+ ++ ++ +++ IVG +G
Sbjct: 274 LGPGVVVEDGVCIRRCTVLRDARIRSHSWLESCIVGWRCRVG 315
>dbj|BAB14882.1| (AK024319) unnamed protein product [Homo sapiens]
Length = 387
Score = 113 bits (281), Expect = 3e-24
Identities = 97/342 (28%), Positives = 157/342 (45%), Gaps = 36/342 (10%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPF-VDEFIIIVKYMKEKI 59
MKA++L G G RLRPLT PKP++ NKPI+ + +E L VD I+ V YM + +
Sbjct: 1 MKALILVGGYGTRLRPLTLSTPKPLVDFCNKPILLHQVEALAAAGVDHVILAVSYMSQVL 60
Query: 60 IETLGDEFHGKPITYVSQVEEE--GTAKAIYSAKDYIEE--EEFFAINGDIYFEQEAIRG 115
+ + + I EEE GTA + A+D + E + FF +N D+ + +
Sbjct: 61 EKEMKAQEQRLGIRISMSHEEEPLGTAGPLALARDLLSETADPFFVLNSDVICD-FPFQA 119
Query: 116 LLHVYKKTKANAALVVKKFDDLSQLGMVKTEG--GYVREIVEKPG-NVGGLANLGIYIFN 172
++ ++ +++V K ++ S+ G+V E G + VEKP V N G+YI +
Sbjct: 120 MVQFHRHHGQEGSILVTKVEEPSKYGVVVCEADTGRIHRFVEKPQVFVSNKINAGMYILS 179
Query: 173 PDVFEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLE-VNEYI 231
P V I+ S E +M +G+ A E GFW DIG+P D L + ++
Sbjct: 180 PAVLRRIQLQPTSIEKE-----VFPIMAKEGQLYA-MELQGFWMDIGQPKDFLTGMCLFL 233
Query: 232 LKTKLKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTS 291
+ K R + SG I+G V + + RIG NC I P S
Sbjct: 234 QSLRQKQPER--------------------LCSGPGIVGNVLVDPSARIGQNCSIGPNVS 273
Query: 292 IGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLG 333
+G + + V I+ ++ ++ +++ IVG +G
Sbjct: 274 LGPGVVVEDGVCIRRCTVLRDARIRSHSWLESCIVGWRCRVG 315
>pir||F71491 probable UDP-glcnac pyrophosphorylase - Chlamydia trachomatis
(serotype D, strain UW3/Cx) >gi|3329076|gb|AAC68233.1|
(AE001333) UDP-GlcNAc Pyrophosphorylase [Chlamydia
trachomatis]
Length = 205
Score = 112 bits (278), Expect = 7e-24
Identities = 65/175 (37%), Positives = 90/175 (51%), Gaps = 2/175 (1%)
Query: 222 WDLLEVNEYILKTKLKHDIRGTVEEGATII--PPVEIGEGTVVRSGSYIIGPVKIGKNCR 279
W +L + E L + I G +EEG + +EI EG V SG+YI GP IG +
Sbjct: 26 WSILTLLEEKLASHTFSGIHGHLEEGVYLKNKETIEIQEGAYVESGAYICGPCIIGPYTQ 85
Query: 280 IGPNCFIRPYTSIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTITA 339
+ +IR +C IG+ EIKNS + ++ A H YVGDS+ G NLGAG A
Sbjct: 86 VRHGAYIRGGVITSSHCVIGHCSEIKNSYLGHHAKAAHFAYVGDSVFGSRVNLGAGVRCA 145
Query: 340 NLRHDNRTIKVEIKGKLEDSGRRKLGAIIGHNVKTGINVTIYPGRKIGSGALVGP 394
N R D +TI G+ ++ R+KLGA +G V G N + PG + S + P
Sbjct: 146 NFRLDGKTIFFHHSGERCNTKRKKLGAFLGRGVSVGCNTVLNPGCYVASATKILP 200
>pir||F81650 UDP-N-acetylglucosamine pyrophosphorylase GlmU-related enzyme
TC0918 [imported] - Chlamydia muridarum (strain Nigg)
>gi|7190946|gb|AAF39710.1| (AE002358)
UDP-N-acetylglucosamine pyrophosphorylase GlmU-related
enzyme [Chlamydia muridarum]
Length = 218
Score = 111 bits (274), Expect = 2e-23
Identities = 64/175 (36%), Positives = 90/175 (50%), Gaps = 2/175 (1%)
Query: 222 WDLLEVNEYILKTKLKHDIRGTVEEGATII--PPVEIGEGTVVRSGSYIIGPVKIGKNCR 279
W +L + E L + I+G +EEG + +EI EG V SG+Y+ GP IG +
Sbjct: 39 WSILTLLEQKLSSHSFSGIQGHLEEGVYLKNKETIEIQEGAYVESGAYLCGPCIIGPYTQ 98
Query: 280 IGPNCFIRPYTSIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTITA 339
+ +IR G +C +G+ EIKNS + + A H YVGDS++G NLGAG A
Sbjct: 99 VRHGAYIRGGVITGAHCVVGHCSEIKNSYLGHYAKAAHFAYVGDSVLGSRVNLGAGVRCA 158
Query: 340 NLRHDNRTIKVEIKGKLEDSGRRKLGAIIGHNVKTGINVTIYPGRKIGSGALVGP 394
N R D I + G D+ R+KLGA +G V G N + PG + S + P
Sbjct: 159 NFRLDGGNIFLRYSGDRYDTQRKKLGAFLGKGVSIGCNTVLNPGCCVVSATKILP 213
>pir||B71146 probable glucose-1 phosphate transferase - Pyrococcus horikoshii
>gi|3256772|dbj|BAA29455.1| (AP000002) 327aa long
hypothetical glucose-1 phosphate transferase [Pyrococcus
horikoshii]
Length = 327
Score = 108 bits (268), Expect = 1e-22
Identities = 91/319 (28%), Positives = 151/319 (46%), Gaps = 44/319 (13%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPF-VDEFIIIVKYMKEKI 59
MK +++A G RL P+T D PK +L + NK I+EYILE + VD +I ++ EK
Sbjct: 1 MKVLIMAGGYATRLWPITKDNPKALLPLGNKTILEYILEKVRELDVDVYISTNRFFAEKF 60
Query: 60 ----IETLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRG 115
+E + ++ V + E+ GT A+ +A + + E+++ + GD F +++
Sbjct: 61 RKYDVELIVED-------TVHEEEKLGTIAAMRNALNILGEDDYLIVAGDNVF-SFSLKD 112
Query: 116 LLHVYKKTKANAALVVKKFDDLSQLGMVKTEGGYVREIVEKPGN-VGGLANLGIYIFNPD 174
+ + A V F+ + G+V E V + EKP N L + G+Y+F D
Sbjct: 113 FVDNFSGKTLIAVYDVGDFELAKRYGVVVLEKDRVIDFEEKPANPKSTLISTGVYLFPRD 172
Query: 175 VF----EFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEY 230
V E++E + G + + ++ G ++ + + G+W DIG LE +
Sbjct: 173 VMKLLNEYLEDGNKDSPGYF-----LQWLLKRGEEIRAYRFDGYWYDIGSADSYLEAMKT 227
Query: 231 ILKTKLKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYT 290
+LK +I+ + A IIPPV I +GT + G IIG PY
Sbjct: 228 LLKESYIEEIQ--ISPYAKIIPPVVIKKGTKI-MGRSIIG-----------------PYA 267
Query: 291 SIGDNCHIGNAVEIKNSII 309
IG+ C I N+ +I +SII
Sbjct: 268 YIGEECIIENS-DISDSII 285
>pir||G72455 probable glucose-1-phosphate thymidylyltransferase APE2291 -
Aeropyrum pernix (strain K1) >gi|5105992|dbj|BAA81303.1|
(AP000064) 239aa long hypothetical glucose-1-phosphate
thymidylyltransferase [Aeropyrum pernix]
Length = 239
Score = 105 bits (259), Expect = 1e-21
Identities = 78/236 (33%), Positives = 132/236 (55%), Gaps = 14/236 (5%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPF-VDEFIIIVKYMKEKI 59
M A++LA G G+RLRPLT+ +PKP+L+VA KP++ + +E L + V+EF+++V Y+KE+I
Sbjct: 1 MLALILAGGYGKRLRPLTEHKPKPLLEVAGKPVLVHQIEWLRYYGVEEFVLLVGYLKERI 60
Query: 60 IETLGD-EFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEF-FAINGDIYFEQEAIRGLL 117
IE +G G ITYV + + GTA A+++A+ IE+E +NGDI + L+
Sbjct: 61 IEEMGSGAKFGVKITYVVEDKPLGTAGALWNARHIIEKENLVLVVNGDIVTNIDP-DPLV 119
Query: 118 HVYKKTKANAALVVKKFDDLSQLGMVKTEGGYVREIVEKPGNVGGLANLGIYIFNPDVFE 177
+ ++ +A A + S G+++ + G V EKP N G+Y + ++ +
Sbjct: 120 RLVREREAVAGIAAVPL--RSPYGILELDDGNVTGFREKPFIYDYWINGGLYAVSKEIVK 177
Query: 178 FIERTQESERGEYEITDTINLMISDGRKVA--YFEYSGFWSDIGRPWDLLEVNEYI 231
++ ++G+ E T T + SDG+ VA Y +W I D+ E ++ I
Sbjct: 178 YL-----PQQGDIEKT-TFPQLASDGKLVAARYEIPPFYWRSIDTFKDIEEASKEI 227
>gb|AAK41261.1| Sugar phosphate nucleotydyl transferase [Sulfolobus solfataricus]
Length = 422
Score = 104 bits (256), Expect = 3e-21
Identities = 118/430 (27%), Positives = 192/430 (44%), Gaps = 61/430 (14%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEY-ILENLDPFVDEFIIIVK-YMKEK 58
+K ++ G+ RLRPLT + K +++ N+P+IEY ILE + EFI VK Y+ +
Sbjct: 10 VKVIIPIGGEATRLRPLTIETSKAAVRLLNRPLIEYTILELAKQGIKEFIFGVKGYVNYR 69
Query: 59 IIETLGDEFHG-------KP---ITYVSQVEEEGTAKAIYSAKDYIE-EEEFFAINGDIY 107
+ L E G KP Y +V+ G A ++ +Y + E + GD
Sbjct: 70 SLFDLFKEGIGFSARYKIKPRVHFKYQPRVDSIGNADSVRINIEYYDINEPIVVVQGDNI 129
Query: 108 FEQEAIRGLLHVYKKTKANAALVVKKFD-DLSQLGMVKTEGGY-VREIVEKPGN----VG 161
F+ + I L ++ + +V+KK++ DLS+ G+ T G +R+ VEKP
Sbjct: 130 FKLD-ITKALEFHESKSSLMTIVLKKYEGDLSEFGVADTTGDLAIRKFVEKPKRREDAPS 188
Query: 162 GLANLGIYIFNPDVFEFIERTQESE---RGEYEI-TDTINLMISDGRKVAYFEYSGFWSD 217
L N GIYI +P++ + + E G+ + D I +I+ G V + W D
Sbjct: 189 DLINTGIYILSPEIRKIFKSNDVKEMYKMGKMDFGKDIIPYLINKGYPVYGYPMKEIWFD 248
Query: 218 IGRPWDLLEVNEYILKTKLKHDIRG-TVEEGATII-----PPVEIGEGTVVRSGS----Y 267
IG P L+ +L T +I G ++ I P + R
Sbjct: 249 IGTPERYLDAMVTLLHTLSDSEIGGIRIDPNRRIFVQGTSPDSRKRRREIQRKFKKGLIK 308
Query: 268 IIGPVKIGKNCRIGPNCFIRPYTSIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVG 327
I G IG++C+IG + +I ++I + IG V+I S IMD Y+GD++
Sbjct: 309 IEGDALIGRHCQIGDDTYIEE-SNIDNFTMIGKGVKIVRSAIMDR------GYIGDNVHI 361
Query: 328 ENTNLGAGTITANLRHDNRTIKVEIKGKLEDSGRRKLGAIIGHNVKTG-----INVTIYP 382
EN+ + RH VEI+ + R + ++I +V G IN IYP
Sbjct: 362 ENSIIA--------RH------VEIRSN-NEKPVRIINSVIADDVIVGEGTEIINSRIYP 406
Query: 383 GRKIGSGALV 392
+ I +G+ +
Sbjct: 407 HKFINAGSRI 416
>pir||C82720 UDP-N-acetylglucosamine pyrophosphorylase XF1140 [imported] -
Xylella fastidiosa (strain 9a5c)
>gi|9106102|gb|AAF83950.1|AE003949_14 (AE003949)
UDP-N-acetylglucosamine pyrophosphorylase [Xylella
fastidiosa]
Length = 457
Score = 104 bits (256), Expect = 3e-21
Identities = 106/461 (22%), Positives = 188/461 (39%), Gaps = 76/461 (16%)
Query: 4 VVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPFVDEFI-IIVKYMKEKIIET 62
V+LAAG+G+R++ PK + +A KP++ +++ + I ++ + ++
Sbjct: 10 VILAAGEGKRMKSAL---PKVLHPIAGKPMLAHVITAAQALTPDAIHVVYGHAGNQVRAA 66
Query: 63 LGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRG--LLHVY 120
D+ + +V Q ++ GT A+ I + +Y + IR L +
Sbjct: 67 FADQ---TDLHWVEQAQQLGTGHAVKQTMSAIPNAANVLV---LYGDVPLIRAETLKRLP 120
Query: 121 KKTKANAALVVKKFDDLSQLGMVKTEGGYVREIVE-----KPGNVGGLANLGIYIFNPDV 175
+ + A LV + + +V+ G V I+E + N GI
Sbjct: 121 RASTPIAVLVTELANPAGYGHIVRNSEGKVAAIIEDKDADEEQRRIHTVNTGILCAESTA 180
Query: 176 FE--FIERTQESERGEYEITDTIN-----------LMISDGRKVAYFEYSGFWSDIGRPW 222
+ + + +GEY +TD +M++D R+V + + R W
Sbjct: 181 LRRWLSKLSNTNMQGEYYLTDIFASATADLTPANMIMVTDAREVEGVNDLWQLTQLERAW 240
Query: 223 DLLEVNEYILK-----TKLKHDIRGTVEEGATIIPPVEIG-EGTVVRSGSYIIGP----- 271
+ L+ + D RGT+ G + +++ EG + + +IGP
Sbjct: 241 QIRAARALCLQGARVADPARLDQRGTIRIGQNVHIDIDVVLEGEIELGDNVVIGPFVRLK 300
Query: 272 -VKIGKNCR-----------------IGPNCFIRPYTSIGDNCHIGNAVEIKNSIIMDNS 313
VK+G + IGP +RP T + D HIGN VE KN+ I +S
Sbjct: 301 NVKLGPGTKVHAHCDLEGVTTTGSALIGPFARLRPGTMLADGVHIGNFVETKNTSIGADS 360
Query: 314 NAPHLNYVGDSIVGENTNLGAGTITANLRHDNRTIKVEIKGKLEDSGRRKLGAIIGHNVK 373
A HL Y+GD+ +G N+GAGTIT N N++I +IG
Sbjct: 361 KANHLTYLGDAQIGTKVNIGAGTITCNYDGINKSI-----------------TLIGDGAF 403
Query: 374 TGINVTIYPGRKIGSGALVGPGVIVDKNIPPNVLVVAKQEK 414
G + + +G+GA +G G ++ + P + L VA+ +
Sbjct: 404 IGSHSALIAPVSVGAGATLGAGTVLTHDAPAHQLTVARSRQ 444
>pir||B75008 glucose-1-phosphate thymidylyltransferase (grad-1) PAB1053 -
Pyrococcus abyssi (strain Orsay)
>gi|5459018|emb|CAB50504.1| (AJ248288)
glucose-1-phosphate thymidylyltransferase (graD-1)
[Pyrococcus abyssi]
Length = 332
Score = 103 bits (255), Expect = 3e-21
Identities = 102/332 (30%), Positives = 155/332 (45%), Gaps = 33/332 (9%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILEN-LDPFVDEFIIIVKYMKEKI 59
MK +++A G RL PLT D+PKP+L V K I+++I+E L+ VDE I E
Sbjct: 1 MKVLIMAGGYATRLWPLTKDKPKPLLPVGIKTILDFIMEKVLELNVDEVYISTNKFFEHK 60
Query: 60 IETLGDEFHGKPITYVSQVEEE--GTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLL 117
+ +++ I + EEE GT AI +A D + +++ I GD F ++R +
Sbjct: 61 FKPYAEKYGVDLIIEDTYREEEKLGTIGAIKNALDSLGLDDYLIIAGDNIFSL-SLRDFV 119
Query: 118 HVYKKTKANAALVVKKFDDLSQLGMVKTEGGYVREIVEKPGN-VGGLANLGIYIFNPDVF 176
+ A V + + G+V EG V + +EKP L + GIY DV
Sbjct: 120 SKFTGKPLIAVYDVGDLELAKRYGVVILEGNRVVKFIEKPQEPPSTLISTGIYALPRDVM 179
Query: 177 ----EFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYIL 232
E+++ + G + I +I G +V +++ FW DIG LE + ++
Sbjct: 180 GMIDEYLKYGNKDAPGYF-----IQWLIERGIEVYAYKFDDFWYDIGSADSYLESLKMLM 234
Query: 233 KTKLKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGP-VKIGKNCRIG---------- 281
K DI+ V + IIPPV I +GT + G IIGP IG+NC I
Sbjct: 235 KESYIGDIK--VSPYSKIIPPVVILDGTRI-EGRSIIGPFAYIGRNCLIENSDVSDSIIF 291
Query: 282 PNCFIRPYT----SIGDNCHIGNAVEIKNSII 309
+ IR T I + C I N +E+K SI+
Sbjct: 292 DSTVIRNSTIWRSIIDEKCEIRN-LELKKSIV 322
>gb|AAK42616.1| Sugar phosphate nucleotydyl transferase [Sulfolobus solfataricus]
Length = 237
Score = 102 bits (252), Expect = 7e-21
Identities = 74/239 (30%), Positives = 121/239 (49%), Gaps = 16/239 (6%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPF-VDEFIIIVKYMKEKI 59
M AV+LA G G+RLRPLTDDRPKP+++VA +PIIE+ + L F + F+I+ Y E +
Sbjct: 4 MHAVILAGGYGKRLRPLTDDRPKPLIEVAGRPIIEWQISWLKQFGITSFVILTGYKWEVL 63
Query: 60 IETLGDEFHGKPITYVSQVEEE--GTAKAIYSAKDYIE-EEEFFAINGDIYFEQEAIRGL 116
I+ L + I+ +EEE GT A+ + + E F +NGDI + +
Sbjct: 64 IKWLSENEKRLGISTYFSIEEEPLGTGGALRKVERLLSTENTFIVLNGDIITNLDISK-- 121
Query: 117 LHVYKKTKANAALVVKKFDDLSQLGMVKTEGGYVREIVEKPGNVGGLANLGIYIFNPDVF 176
L + + +LV K S G+V+T+ + + EKP N G+Y+ ++F
Sbjct: 122 LKISNENVMTMSLVPLK----SPYGIVETKDDKIIDFKEKPILENYWINAGVYLMRKEIF 177
Query: 177 EFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKTK 235
+++ E+G+ E T + + + Y +W I D+ EV+E ++K K
Sbjct: 178 KYL-----PEKGDMEKL-TFPKLAKESLLIGIKYYDVYWRSIDTIKDIEEVSEDLIKMK 230
>sp|P39629|SPSI_BACSU SPORE COAT POLYSACCHARIDE BIOSYNTHESIS PROTEIN SPSI
>gi|2126974|pir||S39726 spore coat polysaccharide
synthesis spsI - Bacillus subtilis
>gi|580880|emb|CAA51627.1| (X73124) ipa-71d [Bacillus
subtilis] >gi|2636319|emb|CAB15810.1| (Z99123) alternate
gene name: ipa-71d [Bacillus subtilis]
Length = 246
Score = 102 bits (252), Expect = 7e-21
Identities = 73/225 (32%), Positives = 116/225 (51%), Gaps = 8/225 (3%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDP--FVDEFIIIVKYMKEK 58
MK V+LA G G RL PLT K +L V P+I + + L D +I K +
Sbjct: 1 MKGVILAGGNGSRLMPLTKAVNKHLLPVGPYPMIYWSIMKLQEAGIKDILLISQKEHMPQ 60
Query: 59 IIETLGD-EFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLL 117
+ LG+ E G ITY Q G + + AK + ++E F + GD FE ++++
Sbjct: 61 FYKLLGNGEELGVTITYQVQPAASGISDGLSYAKRFTKKESFILLLGDNIFE-DSLKPYT 119
Query: 118 HVYKKTKANAALVVKKFDDLSQLGMVKTE--GGYVREIVEKPGNVG-GLANLGIYIFNPD 174
+++ A +++K+ DD + G+ + + +R I+EKP L GIY+++ +
Sbjct: 120 ERFEQQGKGAKVLLKEVDDPERFGIAEIDEKNKRIRSIIEKPEQPPTNLCVTGIYMYDAE 179
Query: 175 VFEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIG 219
VF +IE+ S+RGE EITD NL I + ++ Y SG+W D G
Sbjct: 180 VFSYIEQISPSKRGELEITDVNNLYI-ENSQLTYDVLSGWWVDAG 223
>pir||E75473 UDP-N-acetylglucosamine pyrophosphorylase - Deinococcus radiodurans
(strain R1) >gi|6458522|gb|AAF10386.1|AE001935_5
(AE001935) UDP-N-acetylglucosamine pyrophosphorylase
[Deinococcus radiodurans]
Length = 487
Score = 102 bits (252), Expect = 7e-21
Identities = 108/473 (22%), Positives = 186/473 (38%), Gaps = 97/473 (20%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPFVDEFIIIVKYMKEKII 60
+ V+LAAG+G R+ PK + VA +P++ + ++ I++V + +
Sbjct: 11 LDVVILAAGQGTRMNSAL---PKVLHPVAGRPMVAWAVKAARDLGARKIVVVTGHGAEQV 67
Query: 61 ETLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEE--EEFFAINGDI-YFEQEAIRGLL 117
E + + + Q + GT A S + E + + GD + +R L+
Sbjct: 68 EAAVQQ---PGVAFARQERQLGTGDAFLSGASALTEGGADILVLYGDTPLLRPDTLRELV 124
Query: 118 HVYKKTKANAALVVKKFDDLSQLG-MVKTEGGYVREIVEKPG-----NVGGLANLGIYIF 171
+++ + ++ + D + G +V+ EGG V IVE+ G N G+Y+F
Sbjct: 125 ASHREQGSAMTVLTGELPDATGYGRIVRGEGGAVERIVEQKDASDAEKAIGEFNSGVYVF 184
Query: 172 NPDVFEFIERT-QESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEY 230
+ E R +++ GEY +TD + L + G V F S P ++L N+
Sbjct: 185 DERAPELARRIGNDNKAGEYYLTDLLGLYRAGGATVRAFRLSD-------PDEVLGANDR 237
Query: 231 ILKTKLKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRI---------- 280
T+L+ ++ + EG ++ G + I V+IG++ I
Sbjct: 238 AGLTQLEATLQRRINEGH-----LKAGVSISLPGTVLIEDTVEIGRDVVIEPGALLRGQT 292
Query: 281 ------------------------------------------GPNCFIRPYTSIGDNCHI 298
GP +RP + +G+ HI
Sbjct: 293 RIAGGAVIGAYSVITDSVIHERAVIKAHSVLEQAEVGAGSDVGPFARLRPGSVLGEGVHI 352
Query: 299 GNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTITANLRHDNRTIKVEIKGKLED 358
GN VE KN+ + A HL Y+GD +G TN+GAGTI AN
Sbjct: 353 GNFVETKNARLDAGVKAGHLAYLGDVEIGAETNVGAGTIVANF----------------- 395
Query: 359 SGRRKLGAIIGHNVKTGINVTIYPGRKIGSGALVGPGVIVDKNIPPNVLVVAK 411
G K + +G V G N T+ R +G A + G + ++P + VA+
Sbjct: 396 DGLNKHQSKVGAGVFIGSNTTLIAPRVVGDAAFIAGGSAIHDDVPEGAMAVAR 448
>pir||C69815 glucose-1-phosphate cytidylyltransferase (EC 2.7.7.33) yfnH -
Bacillus subtilis >gi|2116766|dbj|BAA20117.1| (D86418)
YfnH [Bacillus subtilis] >gi|2633040|emb|CAB12546.1|
(Z99107) similar to glucose-1-phosphate
cytidylyltransferase [Bacillus subtilis]
Length = 254
Score = 101 bits (250), Expect = 1e-20
Identities = 81/253 (32%), Positives = 122/253 (48%), Gaps = 35/253 (13%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPF-VDEFIIIVKYMKEKI 59
MKAV+L GKG R+ +T+D PKP+ + KPI+ +I++ + V+EFI+++ Y EKI
Sbjct: 1 MKAVILCGGKGTRMSEVTNDIPKPLAMIGGKPILWHIMKIYQYYGVNEFILLLGYKGEKI 60
Query: 60 IETLGD-----------------EFHGKPITYVSQVEEEG----TAKAIYSAKDYIEEEE 98
E D + G+P T+ E G TA I AKDYI +E
Sbjct: 61 KEYFLDYEWKHNSLTLDSSTGEVQMLGQPETWKITFLETGVDTLTAGRILQAKDYIGDET 120
Query: 99 FFAINGDIYFEQEAIRGLLHV--YKKTKANAALVVKKFDDLSQLGMVKTEGGYVREIVEK 156
F GD A L H+ Y +TK AA V D +SQ G + E G + EK
Sbjct: 121 FLLTYGD----GLANINLFHLISYHQTK-GAAATVTGIDKVSQFGTLTVEDGMAKTFSEK 175
Query: 157 PGNVGGLANLGIYIFNPDVFEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWS 216
+ G+ N G ++ +P VF+++ + + + + + + DG Y Y GFW+
Sbjct: 176 TSS-DGIINGGFFVLSPKVFDYLPKDGNTMFED----EPLKNLAKDGELAVYRHY-GFWT 229
Query: 217 DIGRPWDLLEVNE 229
I +LLEVN+
Sbjct: 230 AIDTYKNLLEVNK 242
>pir||S75920 hypothetical protein - Synechocystis sp. (strain PCC 6803)
>gi|1653465|dbj|BAA18379.1| (D90913) mannose-1-phosphate
guanyltransferase [Synechocystis sp.]
Length = 388
Score = 99.1 bits (243), Expect = 9e-20
Identities = 93/333 (27%), Positives = 152/333 (44%), Gaps = 29/333 (8%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPF-VDEFIIIVKYMKEKI 59
MKA++LAAGKG R+RP+T PKP++ + KP++E++LE L D+ ++ V ++ E+I
Sbjct: 1 MKAMILAAGKGTRVRPITHTIPKPMIPILQKPVMEFLLELLRQHGFDQIMVNVSHLAEEI 60
Query: 60 IETLGD-EFHGKPITYVSQ---VEEEGTAKAIYSAKDYIEEEEF--------FAINGDIY 107
D + G I Y + V+ + KA+ SA + +EF + GD
Sbjct: 61 ESYFRDGQRFGVQIAYSFEGNIVDGDLVGKALGSAGGLKKIQEFNPFFDDTFVVLCGDAL 120
Query: 108 FEQEAIRGLLHVYKKTKANAALVVKKFDD--LSQLGMVKTE-GGYVREIVEKPGNVGGLA 164
+ + + + ++++ A A ++ K +S G+V T+ G + EKP L+
Sbjct: 121 IDLD-LTTAVKLHREKGAIATIITKTVPQELVSSYGVVVTDDNGKILTFQEKPAVEEALS 179
Query: 165 ---NLGIYIFNPDVFEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRP 221
N GIYIF P+V ++I QE + G D ++ G W DIG+
Sbjct: 180 TEINTGIYIFEPEVIDYIPSGQEYDLGG----DLFPKLVDSGLPFYAVNMDFEWVDIGKV 235
Query: 222 WDLLEVNEYILKTKLKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYII-GPVKIGKNCRI 280
D + ++ L +I+ G + P V G + I GPV IG RI
Sbjct: 236 PDYWQA----IRGVLSREIKNVQIPGIEVRPGVYTGINVAANWDNIEIEGPVYIGGMTRI 291
Query: 281 GPNCFIRPYTSIGDNCHIGNAVEIKNSIIMDNS 313
I + IG +C I + NS+I + S
Sbjct: 292 EDGVKIIGPSMIGPSCLICQGAVVDNSVIFEYS 324
>gi|10956341 pXO1-94 [Bacillus anthracis] >gi|7474335|pir||F59102 probable
UTP--glucose-1-phosphate uridylyltransferase (EC
2.7.7.9) pXO1-94 [similarity] - Bacillus anthracis
virulence plasmid pXO1
>gi|4894310|gb|AAD32398.1|AAD32398 (AF065404) pXO1-94
[Bacillus anthracis]
Length = 295
Score = 98.7 bits (242), Expect = 1e-19
Identities = 79/277 (28%), Positives = 132/277 (47%), Gaps = 39/277 (14%)
Query: 2 KAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPFVDEFIIIVKYMKEKIIE 61
KA++ AAG G R P T +PK +L + +KP I+YI+E E IIIV + +IE
Sbjct: 5 KAIIPAAGLGTRFLPATKAQPKEMLPIVDKPTIQYIVEEAVSSGIEDIIIVSGRGKHVIE 64
Query: 62 TLGDEFHG-----------------------KPITYVSQVEEEGTAKAIYSAKDYIEEEE 98
D+ + I Y+ Q E +G AIY A+ +I EE
Sbjct: 65 DHFDKSYELEQTLFKKNKIKTLEDIECISNLANIHYIRQKEPKGLGHAIYCARRFIGEEP 124
Query: 99 FFAINGD--IYFEQEAIRGLLHVYKKTKANAALVVKKFD-DLSQLGMVKTEGGYVRE--- 152
F + GD + ++ L+ VY++ + V + + ++S+ G+VK+ V +
Sbjct: 125 FAVLLGDDIVSSTYPCLKQLIDVYEEHHCSVVGVQRVLETEVSKYGIVKSANQNVNQSII 184
Query: 153 ----IVEKP---GNVGGLANLGIYIFNPDVFEFIERTQESERGEYEITDTINLMISDGRK 205
+VEKP LA +G YI PD+FE ++ GE ++TD IN +++ +K
Sbjct: 185 PISMLVEKPPLETAPSNLAIMGRYILKPDIFEVLKNLPVGSGGEIQLTDAIN-VLNKQQK 243
Query: 206 VAYFEYSGFWSDIGRPWDLLE--VNEYILKTKLKHDI 240
V FE+ G D+G + ++ ++ + + LK D+
Sbjct: 244 VLAFEFDGKRYDVGDKFGFIKATIDFALQRESLKEDV 280
>dbj|BAB07082.1| (AP001518) spore coat polysaccharide synthesis (glucose-1-phosphate
thymidyltransferase) [Bacillus halodurans]
Length = 247
Score = 98.7 bits (242), Expect = 1e-19
Identities = 75/239 (31%), Positives = 125/239 (51%), Gaps = 8/239 (3%)
Query: 2 KAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEY-ILENLDPFVDEFIIIV-KYMKEKI 59
KAV+LA G G RL P+T K +L V + P+I + IL+ + + E +I+ +
Sbjct: 3 KAVILAGGTGSRLSPITRVINKHLLPVGSYPMIYWSILKAKEAGLHEILILTSREHLAAF 62
Query: 60 IETLGD-EFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLLH 118
I+ LGD + G + Y Q + +G A A+ A+ ++ +E+F + GD F + + +
Sbjct: 63 IQLLGDGKDLGVHLHYTIQDQADGIASALSLAEHFVGDEKFLVLLGDNLFA-DPLTAYVQ 121
Query: 119 VYKKTKANAALVVKKFDDLSQLGMVKTEGGY--VREIVEKPGNVGGLANL-GIYIFNPDV 175
Y+K K A +++K+ D ++ G+ + +++IVEKP G + GIY+++ V
Sbjct: 122 QYEKQKEGAFVLLKEVRDPTRYGIAFLDETKQKIKKIVEKPNMQGSAYCVTGIYMYDRTV 181
Query: 176 FEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKT 234
F FIE+ S RGE EITD N I G + + +W D G L + N Y+ +T
Sbjct: 182 FSFIEQIAPSARGELEITDVNNFYIDQG-TMGFNILPDWWIDAGTHESLFKANCYMNQT 239
>gb|AAA62081.1| (L10328) similar to Bacillus subtilis tms; similarity also includes
f190 [Escherichia coli]
Length = 277
Score = 98.3 bits (241), Expect = 1e-19
Identities = 74/277 (26%), Positives = 118/277 (41%), Gaps = 57/277 (20%)
Query: 182 TQESERGEYEITDTINLMISDGRKVA------YFEYSGF-----WSDIGRPWDLLEVNEY 230
T + +GEY ITD I L +GR++ E G S + R + + +
Sbjct: 9 TNNNAQGEYYITDIIALAYQEGREIVAVHPQRLSEVEGVNNRLQLSRLERVYQSEQAEKL 68
Query: 231 I-----LKTKLKHDIRGT--------------VEEGATIIPPVEIGEGTVVR-------- 263
+ L+ + D+RGT +E T+ V+IG G V++
Sbjct: 69 LLAGVMLRDPARFDLRGTLTHGRDVEIDTNVIIEGNVTLGHRVKIGTGCVIKNSVIGDDC 128
Query: 264 --SGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDNCHIGNAVEIKNSIIMDNSNAPHLNYV 321
S ++ + C IGP +RP + + H+GN VE+K + + S A HL Y+
Sbjct: 129 EISPYTVVEDANLAAACTIGPFARLRPGAELLEGAHVGNFVEMKKARLGKGSKAGHLTYL 188
Query: 322 GDSIVGENTNLGAGTITANLRHDNRTIKVEIKGKLEDSGRRKLGAIIGHNVKTGINVTIY 381
GD+ +G+N N+GAGTIT N G K IIG +V G + +
Sbjct: 189 GDAEIGDNVNIGAGTITCNY-----------------DGANKFKTIIGDDVFVGSDTQLV 231
Query: 382 PGRKIGSGALVGPGVIVDKNIPPNVLVVAKQEKIVKE 418
+G GA + G V +N+ N L +++ + KE
Sbjct: 232 APVTVGKGATIAAGTTVTRNVGENALAISRVPQTQKE 268
>gb|AAD31893.2|AF144042_1 (AF144042) dTDP-glucose synthase [Streptomyces rimosus subsp.
paromomycinus]
Length = 256
Score = 98.3 bits (241), Expect = 1e-19
Identities = 68/218 (31%), Positives = 111/218 (50%), Gaps = 8/218 (3%)
Query: 113 IRGLLHVYKKTKANAALVVKKFDDLSQLGMVK-TEGGYVREIVEKPGNV-GGLANLGIYI 170
I G++ ++ T+ L+V K D S G+ + T G V + EKP LA +G+Y+
Sbjct: 15 IAGVVQRFRTTRCGTRLLVTKVPDPSPFGVAEVTPEGRVVRLEEKPARPRSDLAVVGVYL 74
Query: 171 FNPDVFEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEY 230
F V + + S RGE EITD I +I G V G+W D G D+LEVN+
Sbjct: 75 FTSAVHRAVAAIEPSARGELEITDAIQWLIDSGHDVVAETIDGYWKDTGDVADMLEVNQR 134
Query: 231 ILKTKLKHDIRGTVEEGATIIPPVEIGEGT-VVRSGSYIIGPVKIGKNCRIGPNCFIRPY 289
+L L+ +RG V+ + ++ PV I G +VR S I+GP IG + + + I P
Sbjct: 135 VL-ADLEPAVRGAVDSASVLLGPVRIEPGAEIVR--SRIVGPAVIGAHTTV-RDSRIGPA 190
Query: 290 TSIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVG 327
TS+ + C + + +++ SI + ++ + S++G
Sbjct: 191 TSVAEGCAVIES-DVEFSIALRDARITGAGRIEGSLIG 227
>sp|Q58730|YD34_METJA PUTATIVE UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE (UDP-GLUCOSE
PYROPHOSPHORYLASE) (UDPGP) (ALPHA-D-GLUCOSYL-1-PHOSPHATE
URIDYLYLTRANSFERASE) (URIDINE DIPHOSPHOGLUCOSE
PYROPHOSPHORYLASE) >gi|2129351|pir||E64466
UTP--glucose-1-phosphate uridylyltransferase (EC
2.7.7.9) MJ1334 [similarity] - Methanococcus jannaschii
>gi|1591975|gb|AAB99341.1| (U67573) UDP-glucose
pyrophosphorylase (gtaB) [Methanococcus jannaschii]
Length = 283
Score = 96.7 bits (237), Expect = 4e-19
Identities = 72/233 (30%), Positives = 117/233 (49%), Gaps = 32/233 (13%)
Query: 2 KAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPFVDEFIIIVKYMKEKIIE 61
KAV+ AG G RL P+T +PK +L V NKPI++Y++E+L + I+ V ++ IE
Sbjct: 4 KAVIPVAGFGTRLLPITKAQPKEMLPVVNKPIVQYVVEDLVEAGVKDILFVTGKGKQAIE 63
Query: 62 TLGD---------EFHGK--------------PITYVSQVEEEGTAKAIYSAKDYIEEEE 98
D E GK I YV Q E++G AI ++++ EE
Sbjct: 64 NHFDVNYELECKLEKSGKYELLKIIKEIDRLGNIFYVRQKEQKGLGDAILYGEEFVGEEY 123
Query: 99 FFAINGDIYFEQEAIRGLLHVYKKTKANA-ALVVKKFDDLSQLGMVKTE----GGY-VRE 152
F A+ GD + + ++ L+ ++K + AL +D+ + G++ E G Y ++
Sbjct: 124 FIAMVGDTIYSKNIVKDLIKAHEKYGCSVIALERVPKEDVYKYGVIDGEEIEKGVYKIKN 183
Query: 153 IVEKPGNVGGLANL---GIYIFNPDVFEFIERTQESERGEYEITDTINLMISD 202
+VEKP +NL G Y+ +P +FE I T GE +ITD +NL++ +
Sbjct: 184 MVEKPKVEEAPSNLIITGAYLLSPKIFEKIRETPPGRGGEIQITDAMNLLLKE 236
>gb|AAG23610.1|AF244661_1 (AF244661) glucose-1-phosphate thymidylyltransferase
[Carboxydothermus hydrogenoformans]
Length = 197
Score = 96.3 bits (236), Expect = 6e-19
Identities = 57/179 (31%), Positives = 99/179 (54%), Gaps = 3/179 (1%)
Query: 49 IIIVKYMKEKIIETLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYF 108
+II E+I +++ + T++ Q + G A A+ AKDY+E+++F GD
Sbjct: 12 VIIAPETGEEIKKSITNAGFPAKFTFILQEKPLGLAHAVKVAKDYLEDDDFIMYLGDNLI 71
Query: 109 EQEAIRGLLHVYKKTKANAALVVKKFDDLSQLGMVKTEGGY-VREIVEKPGNV-GGLANL 166
I+ + YK+ + +A +++K+ D ++ G+ + + V+ ++EKP LA +
Sbjct: 72 NS-GIKEFVEEYKENRYDATILLKEVQDPTRFGVAVVDENFKVQRLIEKPKEPPSNLALV 130
Query: 167 GIYIFNPDVFEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLL 225
GIYIF+P +F I+R + S RGE EITD I +I+ G V + +G+W D G+ LL
Sbjct: 131 GIYIFSPKIFSAIDRIKPSWRGELEITDAIQELITSGGMVQAHKITGWWLDTGKKDHLL 189
>sp|P75124|GALU_MYCPN UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE (UDP-GLUCOSE
PYROPHOSPHORYLASE) (UDPGP) (ALPHA-D-GLUCOSYL-1-PHOSPHATE
URIDYLYLTRANSFERASE) (URIDINE DIPHOSPHOGLUCOSE
PYROPHOSPHORYLASE) >gi|2146691|pir||S73501 probable
UTP--glucose-1-phosphate uridylyltransferase (EC
2.7.7.9) gtaB [similarity] - Mycoplasma pneumoniae
(strain ATCC 29342) >gi|1673837|gb|AAB95823.1|
(AE000018) UDP-glucose pyrophosphorylase [Mycoplasma
pneumoniae]
Length = 291
Score = 95.2 bits (233), Expect = 1e-18
Identities = 77/274 (28%), Positives = 123/274 (44%), Gaps = 39/274 (14%)
Query: 2 KAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILEN-LDPFVDEFIIIVKYMKEKII 60
KAV+ AAG G RL P T PK +L + NKP I+YI+E + + E ++IV KE II
Sbjct: 6 KAVIPAAGLGTRLLPATKAIPKEMLPLVNKPTIQYIVEEAVASGIKEILVIVSSKKEAII 65
Query: 61 ETLGDEF----------------------HGKPITYVSQVEEEGTAKAIYSAKDYIEEEE 98
+ +F + I +V Q + G AI AK ++ E+
Sbjct: 66 DHFDYDFILENALLQKHKDQEHQEIKDIANLAHIYFVRQKHQHGLGDAILHAKSFVGNED 125
Query: 99 FFAINGD--IYFEQEAIRGLLHVYKKTKANAALVVK-KFDDLSQLGMVKTEGGYVRE--- 152
F + GD ++ EQ A+ + Y++T V + D +++ G+V E + ++
Sbjct: 126 FAVLLGDDVVFGEQPALAQCIQAYEQTDCQVIGVQEVPHDQVNKYGIVTPEANWQKQALV 185
Query: 153 ----IVEKPGNVGGLANLGI---YIFNPDVFEFIERTQESERGEYEITDTINLMISDGRK 205
+VEKP +NL I YI P +F +++ GE ++TD +N + G
Sbjct: 186 KILGMVEKPAVNEAKSNLAILSRYILKPSIFTALKQVPFGVGGELQLTDGLNYCLQQGEP 245
Query: 206 VAYFEYSGFWSDIGRPWDLLEVNEYILKTKLKHD 239
+ G D+G ++ N Y T LK D
Sbjct: 246 FFAKHFGGTRFDVGTKNGFIKANLY---TALKTD 276
>gb|AAA62180.1| (M92842) tms [Listeria monocytogenes]
Length = 251
Score = 94.4 bits (231), Expect = 2e-18
Identities = 55/186 (29%), Positives = 88/186 (46%), Gaps = 32/186 (17%)
Query: 244 VEEGATIIPPVEIGEGTVVRSGSYIIGPV---------------KIGKNCRIGPNCFIRP 288
+E G + IG+ VV SGS I+ V K+G + +IGP +RP
Sbjct: 69 IEPGVMLRGKTVIGDDCVVTSGSEIVNSVIGERVHVRTSSIFESKVGDDVQIGPYAHLRP 128
Query: 289 YTSIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTITANLRHDNRTI 348
+ I D+ IGN VE K +++ + + PH Y+GD+ +G+N N+G G+I N
Sbjct: 129 ESDIHDHVKIGNYVETKKAVVGEGTKLPHFIYMGDAEIGKNVNVGCGSIAVNY------- 181
Query: 349 KVEIKGKLEDSGRRKLGAIIGHNVKTGINVTIYPGRKIGSGALVGPGVIVDKNIPPNVLV 408
G+ K IIG NV G N + K+G A + G + K++P + L
Sbjct: 182 ----------DGKNKAKTIIGDNVFVGCNSNLIAPVKVGDRAFIAAGSTITKDVPEDALG 231
Query: 409 VAKQEK 414
+A+ ++
Sbjct: 232 IARAKQ 237
>pir||H70446 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) galF
[similarity] - Aquifex aeolicus
>gi|2984025|gb|AAC07568.1| (AE000752) UDP-glucose
pyrophosphorylase [Aquifex aeolicus]
Length = 297
Score = 94.0 bits (230), Expect = 3e-18
Identities = 83/281 (29%), Positives = 135/281 (47%), Gaps = 41/281 (14%)
Query: 2 KAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPFVDEFIIIVKYMKEKIIE 61
K V+ AG G R P T PK +L + +KPII++I+E+ E II V +K IE
Sbjct: 6 KVVLPVAGWGTRFLPATKAMPKEMLPIIDKPIIQFIVESFINIGIENIIFVTGRHKKAIE 65
Query: 62 TLGDEFH---------GK---------------PITYVSQVEEEGTAKAIYSAKDYIEEE 97
D H GK PI YV Q E+ G A+ A+ + +E
Sbjct: 66 DHFDHNHELEEHLKKAGKEKLLREVVKISSLINPI-YVRQKEQLGLGHAVLMAEPAVSQE 124
Query: 98 EFFAINGDIYF--EQEAIRGLLHVYKK-TKANAALVVKKFDDLSQLGMVKT-----EGGY 149
FF GDI E+E ++ ++H+++K + AL+ +++S+ G+ K E
Sbjct: 125 PFFVALGDIIVENEEEELKKMIHLFRKFGNSIVALMEVPKEEVSKYGIAKVKKLDEETYI 184
Query: 150 VREIVEKPGNVGGLANLGI---YIFNPDVFEFIERTQESERGEYEITDTINLMISDGRKV 206
+ ++VEKP +NL I YIF P +FE ++ T+ + GE ++TD + L++ + +
Sbjct: 185 IVDLVEKPSPEEAPSNLAIVGRYIFTPTIFEKLKVTKPGKGGEIQLTDAMRLLLEE-EAI 243
Query: 207 AYFEYSGFWSDIGRPWDLLE-VNEYILKTKLKHDIRGTVEE 246
+ + D G P D L+ V + L+ + DI G + E
Sbjct: 244 YACKVNNTVYDTGNPKDYLKTVISFALR---REDINGELIE 281
>dbj|BAB05135.1| (AP001512) mannose-1-phosphate guanyltransferase [Bacillus
halodurans]
Length = 249
Score = 94.0 bits (230), Expect = 3e-18
Identities = 67/234 (28%), Positives = 119/234 (50%), Gaps = 12/234 (5%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPF-VDEFIIIVKYMKEKI 59
MK V+LA G+G RL+PLTD PKP+L +A P + + L +L + + +++V Y+ ++
Sbjct: 1 MKGVILAGGRGTRLKPLTDQIPKPMLPIAGVPCLAHGLAHLAAHGIRDIVMLVHYLNHQM 60
Query: 60 IETLGD-EFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLLH 118
D +G ITYV + GTA ++ +A+ Y+ +E F ++GD+ +I+ +
Sbjct: 61 KAYFQDGSKYGMRITYVQEDAPLGTAGSLKAAERYL-DEPFVVMSGDV-LTTISIQEAIV 118
Query: 119 VYKKTKANAALVVKKFDDLSQLGMVKTEGGY-VREIVEKPGNVGG---LANLGIYIFNPD 174
+K+ + ++ K+ + G+V+T + V EKP L N G+Y+ +P
Sbjct: 119 FHKRQNSLMTMLTKRVKNGQNYGVVQTGPNHRVVAFREKPTEDKTREVLVNTGLYVMDPF 178
Query: 175 VFEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVN 228
V +I + + G+ D I ++ + E G+W DIG D L+ N
Sbjct: 179 VLSYIPKGSAVDLGK----DVIPYLVDRKLDIFALEGGGYWRDIGSFHDYLQAN 228
>pir||T45492 N-acetylglucosamine-1-phosphate uridyltransferase [imported] -
Thiobacillus ferrooxidans (fragment)
>gi|2654002|gb|AAC21669.1| (AF032884)
N-acetylglucosamine-1-phosphate uridyltransferase
[Acidithiobacillus ferrooxidans]
Length = 182
Score = 93.2 bits (228), Expect = 5e-18
Identities = 64/182 (35%), Positives = 92/182 (50%), Gaps = 22/182 (12%)
Query: 230 YILKTKLKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPY 289
++ + L H +R V GA ++ IG+ + S+I G +IG RIGP IRP
Sbjct: 6 FVGEVHLGHRVR--VGAGA-VLQDARIGDDVEILPYSHIEG-AQIGAGARIGPFARIRPG 61
Query: 290 TSIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTITANLRHDNRTIK 349
T IG+ HIGN VE+K + I S A HL+Y+GD+ +G N+GAGTIT N
Sbjct: 62 TEIGER-HIGNYVEVKAAKIGAGSKANHLSYLGDAEIGTGVNVGAGTITCNY-------- 112
Query: 350 VEIKGKLEDSGRRKLGAIIGHNVKTGINVTIYPGRKIGSGALVGPGVIVDKNIPPNVLVV 409
G K IIG++V G + + IG GA +G G + K +PP L +
Sbjct: 113 ---------DGANKHRTIIGNDVFIGSDSQLVAPVNIGDGATIGAGSTITKEVPPGGLTL 163
Query: 410 AK 411
++
Sbjct: 164 SR 165
>pir||E81354 UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.23) Cj0821
[imported] - Campylobacter jejuni (strain NCTC 11168)
>gi|6968267|emb|CAB73086.1| (AL139076)
UDP-N-acetylglucosamine pyrophosphorylase [Campylobacter
jejuni]
Length = 429
Score = 93.2 bits (228), Expect = 5e-18
Identities = 109/446 (24%), Positives = 186/446 (41%), Gaps = 61/446 (13%)
Query: 4 VVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPFVDEFIIIVKYMKEKIIETL 63
++LAAG G R++ +PK + ++ K +I +IL+ D+ +++ + KE++ + +
Sbjct: 6 LILAAGLGTRIK---SQKPKVLQELCQKSMILHILKKAFALSDDVSVVLSHQKERVEKEI 62
Query: 64 GDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDI-YFEQEAIRGLLHVYKK 122
+ F I GTA A+ + + E + GD+ EQ ++ LL
Sbjct: 63 LEYFPKTQILEQDLQNYPGTAGALSGFEP--KNERVLILCGDMPLVEQTSLEALLG---- 116
Query: 123 TKANAALVVKKFDDLSQLGMVKTEGGYVREIVE-KPGNVG----GLANLGIYIFNP---- 173
A L V K D G V + V +IVE K N N G+Y+ +
Sbjct: 117 NNAKLNLAVFKARDPKSYGRVVIKNDSVEKIVEFKDANTQEKEINTCNAGVYVIDSRLLK 176
Query: 174 DVFEFIERTQESERGEYEITDTINLMISDGRKV-AYF----EYSG----FWSDIGRPWDL 224
++ I+ ++ EY +TD + L + A F E+ G F I +
Sbjct: 177 ELLPLIDNNNAAK--EYYLTDIVKLAKEKDVMIKAVFVDEDEFMGINDKFELSIAENFMQ 234
Query: 225 LEVNEYILKTKLKHDIRGTVEEGATI--IPPVEIGEGTVVRSGSYIIGPV---------K 273
++ +Y ++ + + + GA + + E+ E + S II +
Sbjct: 235 KKIKKYWMQQGVIFHLPQSTFIGADVEFVGECEVYENVRIEGKSKIINSIIKSSSVIENS 294
Query: 274 IGKNCRIGPNCFIRPYTSIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLG 333
I +N +GP +RP + N HIGN VE KN+ + + A HL+Y+GD + TN+G
Sbjct: 295 IVENSDVGPLAHLRPNCEL-KNTHIGNFVECKNAKL-NTVKAGHLSYLGDCEIDSGTNIG 352
Query: 334 AGTITANLRHDNRTIKVEIKGKLEDSGRRKLGAIIGHNVKTGINVTIYPGRKIGSGALVG 393
GTIT N G +K IIG NV G + KI ++
Sbjct: 353 CGTITCNY-----------------DGVKKHKTIIGKNVFVGSDTQFIAPVKIEDEVIIA 395
Query: 394 PGVIVDKNIPPNVLVVAKQ-EKIVKE 418
G V N+ L + + K++K+
Sbjct: 396 AGSTVSINVEKGALFINRAGHKMIKD 421
>sp|Q05852|GTAB_BACSU UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE (UDP-GLUCOSE
PYROPHOSPHORYLASE) (UDPGP) (ALPHA-D-GLUCOSYL-1-PHOSPHATE
URIDYLYLTRANSFERASE) (URIDINE DIPHOSPHOGLUCOSE
PYROPHOSPHORYLASE) (GENERAL STRESS PROTEIN 33) (GSP33)
>gi|538943|pir||A40650 UTP--glucose-1-phosphate
uridylyltransferase (EC 2.7.7.9) gtaB [validated] -
Bacillus subtilis >gi|289287|gb|AAA71967.1| (L12272)
UDP-glucose pyrophosphorylase [Bacillus subtilis]
>gi|405623|emb|CAA80241.1| (Z22516) UDP-glucose
pyrophosphorylase [Bacillus subtilis]
>gi|2636093|emb|CAB15584.1| (Z99122)
UTP-glucose-1-phosphate uridylyltransferase [Bacillus
subtilis]
Length = 292
Score = 92.4 bits (226), Expect = 8e-18
Identities = 75/252 (29%), Positives = 123/252 (48%), Gaps = 35/252 (13%)
Query: 2 KAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPFVDEFIIIVKYMKEKIIE 61
KA++ AAG G R P T PK +L + +KP I+YI+E E IIIV ++ IE
Sbjct: 6 KAIIPAAGLGTRFLPATKAMPKEMLPIVDKPTIQYIIEEAVEAGIEDIIIVTGKSKRAIE 65
Query: 62 TLGD---------EFHGK--------------PITYVSQVEEEGTAKAIYSAKDYIEEEE 98
D E GK I Y+ Q E +G A++ A+++I +E
Sbjct: 66 DHFDYSPELERNLEEKGKTELLEKVKKASNLADIHYIRQKEPKGLGHAVWCARNFIGDEP 125
Query: 99 FFAINGD--IYFEQEAIRGLLHVYKKTKANAALVVK-KFDDLSQLGMV---KTEGG--YV 150
F + GD + E +R L+ Y+KT ++ V + ++ + G++ +EG V
Sbjct: 126 FAVLLGDDIVQAETPGLRQLMDEYEKTLSSIIGVQQVPEEETHRYGIIDPLTSEGRRYQV 185
Query: 151 REIVEKPGN---VGGLANLGIYIFNPDVFEFIERTQESERGEYEITDTINLMISDGRKVA 207
+ VEKP LA LG Y+F P++F ++E Q GE ++TD I +++ ++V
Sbjct: 186 KNFVEKPPKGTAPSNLAILGRYVFTPEIFMYLEEQQVGAGGEIQLTDAIQ-KLNEIQRVF 244
Query: 208 YFEYSGFWSDIG 219
+++ G D+G
Sbjct: 245 AYDFEGKRYDVG 256
>sp|P39122|GLGC_BACSU GLUCOSE-1-PHOSPHATE ADENYLYLTRANSFERASE (ADP-GLUCOSE SYNTHASE)
(ADP-GLUCOSE PYROPHOSPHORYLASE) >gi|1071860|pir||S40049
glucose-1-phosphate adenylyltransferase (EC 2.7.7.27)
glgC - Bacillus subtilis >gi|397489|emb|CAA81041.1|
(Z25795) ADP-glucose pyrophosphorylase [Bacillus
subtilis] >gi|2293137|gb|AAC00215.1| (AF008220)
ADP-glucose pyrophosphorylase [Bacillus subtilis]
>gi|2635581|emb|CAB15075.1| (Z99119) glucose-1-phosphate
adenylyltransferase [Bacillus subtilis]
Length = 380
Score = 90.5 bits (221), Expect = 3e-17
Identities = 90/351 (25%), Positives = 166/351 (46%), Gaps = 41/351 (11%)
Query: 3 AVVLAAGKGERLRPLTDDRPKPILKVANK-PIIEYILENL-DPFVDEFIIIVKYMKEKII 60
A++LA GKG RL LT + KP + K II++ L N + +D I+ +Y ++
Sbjct: 7 AMLLAGGKGSRLSGLTKNMAKPAVSFGGKYRIIDFTLSNCSNSGIDTVGILTQYQPLELN 66
Query: 61 ETLG-------DEFHG-----KPITYVSQVE-EEGTAKAIYSAKDYIEE---EEFFAING 104
+G D ++G P S+V+ +GTA +IY +Y+ + E ++G
Sbjct: 67 SYIGIGSAWDLDRYNGGVTVLPPYAESSEVKWYKGTASSIYENLNYLNQYDPEYVLILSG 126
Query: 105 DIYFEQEAIRGL-LHVYKKTKANAALVVKKFDDLSQLGMVKTE-GGYVREIVEKPG-NVG 161
D ++ + + L H+ KK +++ +++ S+ G++K G + EKP
Sbjct: 127 DHIYKMDYGKMLDYHIEKKADVTISVIEVGWEEASRFGIMKANPDGTITHFDEKPKFPKS 186
Query: 162 GLANLGIYIFN-PDVFEFIERTQESERGEYEI-TDTINLMISDGRKVAYFEYSGFWSDIG 219
LA++GIYIFN P + +++E ++ ++ D I L++ + +K++ + + G+W D+G
Sbjct: 187 NLASMGIYIFNWPLLKQYLEMDDQNPYSSHDFGKDIIPLLLEEKKKLSAYPFKGYWKDVG 246
Query: 220 RPWDLLEVNEYILK--TKLKHDIRGTVEEGATIIPPVE------------IGEGTVVR-- 263
L E N +LK ++LK R P + + EG VV
Sbjct: 247 TVQSLWEANMDLLKEDSELKLFERKWKIYSVNPNQPPQFISSDAQVQDSLVNEGCVVYGN 306
Query: 264 -SGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDNCHIGNAVEIKNSIIMDNS 313
S S + V +GK+ + + I P +IG++ I NA+ ++ D +
Sbjct: 307 VSHSVLFQGVTVGKHTTV-TSSVIMPDVTIGEHVVIENAIVPNGMVLPDGA 356
>sp|P55464|RFBA_RHISN PROBABLE GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (DTDP-GLUCOSE
SYNTHASE) (DTDP-GLUCOSE PYROPHOSPHORYLASE)
>gi|2182410|gb|AAB91682.1| (AE000074) Y4gH [Rhizobium
sp. NGR234]
Length = 286
Score = 90.5 bits (221), Expect = 3e-17
Identities = 74/237 (31%), Positives = 107/237 (44%), Gaps = 6/237 (2%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLD-PFVDEFIIIVKYMKEKI 59
MK ++LA G G RL P+T K IL V +KP+I Y L L + E +II +
Sbjct: 1 MKGIILAGGSGTRLHPMTLVMSKQILPVYDKPMIFYPLTTLMLAGIREILIISTPHHMPL 60
Query: 60 IET-LGDEFH-GKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLL 117
+ LGD G + Y Q G A+A D++ I GD + ++GLL
Sbjct: 61 FQALLGDGSQWGISLRYAVQPSPNGLAQAYVIGADFVAGSPSCLILGDNIYFGHGLQGLL 120
Query: 118 HVYKKTKANAALVVKKFDDLSQLGMVK-TEGGYVREIVEKPGNVGGL-ANLGIYIFNPDV 175
+ A + +D + G+V+ EG I EKP A G+Y ++ +V
Sbjct: 121 QQAAALQQGATIFAYHVNDPERYGVVEFDEGMNALSIEEKPAAPKSTWAVTGLYFYDSEV 180
Query: 176 FEFIERTQESERGEYEITDTINLMISDGR-KVAYFEYSGFWSDIGRPWDLLEVNEYI 231
+ + S RGEYEITD + + G+ KVA W D G P LLE E++
Sbjct: 181 VDIAANLKPSARGEYEITDVNRIYLERGKLKVAVLGRGYAWLDTGTPDSLLEAAEFV 237
>pir||A70978 probable rmlA2 protein - Mycobacterium tuberculosis (strain H37RV)
>gi|1877319|emb|CAB07091.1| (Z92771) rmlA2
[Mycobacterium tuberculosis]
Length = 359
Score = 89.3 bits (218), Expect = 7e-17
Identities = 86/338 (25%), Positives = 145/338 (42%), Gaps = 19/338 (5%)
Query: 3 AVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPFVDEFIIIVKYMKEKIIET 62
AVVL GKG RLRPLT PKP+L A P + ++L + E +I+ K + E
Sbjct: 8 AVVLVGGKGTRLRPLTLSAPKPMLPTAGLPFLTHLLSRIAAAGIEHVILGTSYKPAVFEA 67
Query: 63 -LGD-EFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLLHVY 120
GD G I YV++ GT I + + + NGD+ + + LL +
Sbjct: 68 EFGDGSALGLQIEYVTEEHPLGTGGGIANVAGKLRNDTAMVFNGDVLSGAD-LAQLLDFH 126
Query: 121 KKTKANAALVVKKFDDLSQLGMVKT-EGGYVREIVEKPGN-VGGLANLGIYIFNPDVFEF 178
+ +A+ L + + D G V T E V +EK + N G Y+F +V
Sbjct: 127 RSNRADVTLQLVRVGDPRAFGCVPTDEEDRVVAFLEKTEDPPTDQINAGCYVFERNV--- 183
Query: 179 IERTQESERGEYEITDTINLMISDGR-KVAYFEYSGFWSDIGRPWDLLEVNEYILK-TKL 236
I+R + E + +++DG K+ + + +W D+G P D + + +++
Sbjct: 184 IDRIPQGREVSVE-REVFPALLADGDCKIYGYVDASYWRDMGTPEDFVRGSADLVRGIAP 242
Query: 237 KHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDNC 296
+RG E + +G V G+ +IG +G+ IGP + I D
Sbjct: 243 SPALRGHRGEQL-------VHDGAAVSPGALLIGGTVVGRGAEIGPGTRL-DGAVIFDGV 294
Query: 297 HIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGA 334
+ I+ SII + + D ++G+ ++GA
Sbjct: 295 RVEAGCVIERSIIGFGARIGPRALIRDGVIGDGADIGA 332
>dbj|BAA84594.1| (AB032523) glucose-1-phosphate thymidyltransferase [Streptomyces
avermitilis]
Length = 299
Score = 88.5 bits (216), Expect = 1e-16
Identities = 73/247 (29%), Positives = 108/247 (43%), Gaps = 6/247 (2%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILE--NLDPFVDEFIIIVKYMKEK 58
MK +VLA G G RL PLT K +L V +KP+I Y L L D +I E+
Sbjct: 1 MKGIVLAGGTGSRLYPLTRALSKQLLPVYDKPMIYYPLSVLMLGGIKDILVISSPDHLEQ 60
Query: 59 IIETLGDEFH-GKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLL 117
LGD G I Y +Q G A+A D+I +++ + GD F LL
Sbjct: 61 FRRLLGDGSRLGLNIDYAAQQRPGGIAEAFLIGADFIGQDQVSLVLGDNIFHGMGFSHLL 120
Query: 118 HVYKKTKANAALVVKKFDDLSQLGMVKTE-GGYVREIVEKP-GNVGGLANLGIYIFNPDV 175
+ + L D + G+ + + G + + EKP LA G+Y+++ DV
Sbjct: 121 RSHTRDVDGCVLFGYAVTDPERYGVGEVDASGKLLSVEEKPTAPRSNLAITGLYLYDNDV 180
Query: 176 FEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGF-WSDIGRPWDLLEVNEYILKT 234
E + S RGE EITD +++GR GF W D G L+ +Y+
Sbjct: 181 IEVARGIRSSARGELEITDVNRAYLAEGRARLVDLGRGFTWLDAGTHDSLMHAGQYVQVL 240
Query: 235 KLKHDIR 241
+ + +R
Sbjct: 241 EKRQGVR 247
>pir||G81287 probable sugar-phosphate nucleotidyltransferase Cj1423c [imported]
- Campylobacter jejuni (strain NCTC 11168)
>gi|6968852|emb|CAB73847.1| (AL139078) putative
sugar-phosphate nucleotidyltransferase [Campylobacter
jejuni]
Length = 221
Score = 88.5 bits (216), Expect = 1e-16
Identities = 59/178 (33%), Positives = 88/178 (49%), Gaps = 8/178 (4%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENL-DPFVDEFIIIVKYMKEKI 59
M+A++L G G RL+ + D PKP+ + +KP +E+I E L + E I+ V Y E I
Sbjct: 1 MQAIILCGGLGTRLKSIIKDIPKPMAPINDKPFLEFIFEYLKKQGIKEVILAVSYKYEVI 60
Query: 60 IETLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLLHV 119
E DEF G I Y + E GT AI +++ E + +NGD +F+ + L
Sbjct: 61 KEYFKDEFLGIKIKYSIEKEPLGTGGAIKETLKFVKNEA-YVLNGDTFFDID-----LSK 114
Query: 120 YKKTKANAALVVKKFDDLSQLGMVKT-EGGYVREIVEKPGNVGGLANLGIYIFNPDVF 176
K ++ L +K+ +D + G V E V EK GL N GIY+ D+F
Sbjct: 115 LKLNESKICLALKQMNDFDRYGTVNVDEQDLVISFEEKVFKKQGLINGGIYLLTKDIF 172
>dbj|BAA91460.1| (AK000999) unnamed protein product [Homo sapiens]
Length = 420
Score = 88.2 bits (215), Expect = 2e-16
Identities = 85/365 (23%), Positives = 153/365 (41%), Gaps = 50/365 (13%)
Query: 1 MKAVVLAAG--KGERLRPLTDDRPKPILKVANKPIIEYILENLD--PFVDEFIIIVKYMK 56
+KAV+L G KG R RPL+ + PKP+ VA P+I++ +E P + E ++I Y
Sbjct: 2 LKAVILIGGPQKGTRFRPLSFEVPKPLFPVAGVPMIQHHIEACAQVPGMQEILLIGFYQP 61
Query: 57 EK----IIETLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYI---EEEEFFAINGDIYFE 109
++ +E EF+ P+ Y+ + GT +Y +D I E FF +N D+Y +
Sbjct: 62 DEPLTQFLEAAQQEFN-LPVRYLQEFAPLGTGGGLYHFRDQILAGSPEAFFVLNADVYSD 120
Query: 110 QEAIRGLLHVYKKTKANAALVVKKFDDLSQLG----MVKTEGGYVREIVEKPGN-VGGLA 164
+ +L +++ + L+ + L + + V VEKP + +
Sbjct: 121 FP-LSAMLEAHRRQRHPFLLLGTTANRTQSLNYGCIVENPQTHEVLHYVEKPSTFISDII 179
Query: 165 NLGIYIFNPDVFEFIERTQESERGEYEITDTINLMISDGR---------------KVAYF 209
N GIY+F+P+ + + + + + ++ D+ L G ++
Sbjct: 180 NCGIYLFSPEALKPLRDVFQRNQQDGQLEDSPGLWPGAGTIRLEQDVFSALAGQGQIYVH 239
Query: 210 EYSGFWSDIGRPWDLLEVNE-YILKTKLKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYI 268
G WS I L + Y+ + + H P + + T G +I
Sbjct: 240 LTDGIWSQIKSAGSALYASRLYLSRYQDTH--------------PERLAKHTP--GGPWI 283
Query: 269 IGPVKIGKNCRIGPNCFIRPYTSIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGE 328
G V I ++ P+ + P SIG +G V ++ SI++ + V SIVG
Sbjct: 284 RGNVYIHPTAKVAPSAVLGPNVSIGKGVTVGEGVRLRESIVLHGATLQEHTCVLHSIVGW 343
Query: 329 NTNLG 333
+ +G
Sbjct: 344 GSTVG 348
>gb|AAF81069.1|AF223364_4 (AF223364) mannose-1-phosphate-guanyltransferase-like protein
[Myxococcus xanthus]
Length = 342
Score = 87.8 bits (214), Expect = 2e-16
Identities = 85/354 (24%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPFVDEFIIIVKYMKEKII 60
MKA+VL AG G RLRPLT+ PKP + +P++ Y L L + I + +
Sbjct: 1 MKAMVLCAGLGTRLRPLTERWPKPAMPFLGQPLLRYHLAVLKAAGVTAVGINTHHLPDTM 60
Query: 61 ETLGD---EFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLL 117
E + G P+ V++ +GT I +D++ + +F NGDI + + +R ++
Sbjct: 61 EAVARAECARAGLPLHVVNEPVIQGTGGGIRGLRDFLSDGDFIVFNGDILYPVD-LRPVV 119
Query: 118 HVYKKTKANAALVVKKFDDLSQLGMVKTEG-GYVREIVEKPGNVGGLAN---LGIYIFNP 173
+++ + A A +V++ V+ + G VR I GL+ G+++ +P
Sbjct: 120 ALHQASGALATMVLQPMPAGETYAAVELDAEGRVRRIAGHGPGGEGLSPWHFTGVHVMSP 179
Query: 174 DVFEFIERTQESERGEYEITDTINLMISD-GRKVAYFEYSGFWSDIGRPWDLLEVNEYIL 232
VF+F+ S RGE +I + + + G+ V G+WSD+G P L + +L
Sbjct: 180 RVFDFM-----SPRGEEDINRGVYVRAMEAGQMVRGVRVDGYWSDLGTPSRYLATVQDVL 234
Query: 233 KTKLKHDIRGTVEEGATIIPPVEIGEGT----VVRSGSYIIGPVKIGKNCRIGPNCFIRP 288
++ + G + + V GT R GPV +G+ + + P
Sbjct: 235 AGHVRLEWLGA---DSPLAGTVRGASGTWAHAEARLDGTAEGPVYLGRGSAVAAGAAVGP 291
Query: 289 YTSIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTITANLR 342
S+ + + + + +++ G+S+ E GA I A L+
Sbjct: 292 GVSLEPGAKVAAGARLSRATVFEDTEVSS----GESL-SEVLAWGAHRIAAPLK 340
>gb|AAC78674.1| (AF094575) glucose-1-phosphate thimidylyl transferase Cps19aL
[Streptococcus pneumoniae]
Length = 289
Score = 87.0 bits (212), Expect = 4e-16
Identities = 70/238 (29%), Positives = 111/238 (46%), Gaps = 8/238 (3%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPFVDEFIIIVKYMKE--- 57
MK ++LA G G RL PLT K ++ V +KP+I Y L L + I+I+ ++
Sbjct: 1 MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLAGIKDILIISTPQDLPR 60
Query: 58 -KIIETLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGL 116
K + G EF G ++Y Q +G A+A +++I ++ I GD + + +
Sbjct: 61 FKDLLLDGSEF-GIKLSYAEQPSPDGLAQAFLIGEEFIGDDSVALILGDNIYHGPGLSTM 119
Query: 117 LHVYKKTKANAALVVKKFDDLSQLGMVKTEGGY-VREIVEKPGNV-GGLANLGIYIFNPD 174
L K + A + + D + G+V+ + I EKP A G+Y ++ D
Sbjct: 120 LQKAAKKEKGATVFGYQVKDPERFGVVEFDTDMNAISIEEKPEYPRSNYAVTGLYFYDND 179
Query: 175 VFEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGF-WSDIGRPWDLLEVNEYI 231
V E ++ + S RGE EITD ++ G GF W D G LLE ++YI
Sbjct: 180 VVEIAKQIKPSARGELEITDVNKAYLNRGDLSVELMGRGFAWLDTGTHESLLEASQYI 237
>gb|AAD19913.1| (AF105113) glucose-1-phosphate thymidylyl transferase
[Streptococcus pneumoniae]
Length = 289
Score = 87.0 bits (212), Expect = 4e-16
Identities = 70/238 (29%), Positives = 111/238 (46%), Gaps = 8/238 (3%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPFVDEFIIIVKYMKE--- 57
MK ++LA G G RL PLT K ++ V +KP+I Y L L + I+I+ ++
Sbjct: 1 MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLAGIKDILIISTPQDLPR 60
Query: 58 -KIIETLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGL 116
K + G EF G ++Y Q +G A+A +++I ++ I GD + + +
Sbjct: 61 FKDLLLDGSEF-GIKLSYAEQPSPDGLAQAFLIGEEFIGDDSVALILGDNIYHGPGLSTM 119
Query: 117 LHVYKKTKANAALVVKKFDDLSQLGMVKTEGGY-VREIVEKPGNV-GGLANLGIYIFNPD 174
L K + A + + D + G+V+ + I EKP A G+Y ++ D
Sbjct: 120 LQKAAKKEKGATVFGYQVKDPERFGVVEFDTDMNAISIEEKPEYPRSNYAVTGLYFYDND 179
Query: 175 VFEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGF-WSDIGRPWDLLEVNEYI 231
V E ++ + S RGE EITD ++ G GF W D G LLE ++YI
Sbjct: 180 VVEIAKQIKPSARGELEITDVNKAYLNRGDLSVELMGRGFAWLDTGTHESLLEASQYI 237
>gb|AAD22341.1|AC006955_27 (AC006955) putative GDP-mannose pyrophosphorylase [Arabidopsis
thaliana]
Length = 385
Score = 87.0 bits (212), Expect = 4e-16
Identities = 92/388 (23%), Positives = 165/388 (41%), Gaps = 52/388 (13%)
Query: 3 AVVLAAG--KGERLRPLTDDRPKPILKVANKPIIEYILENLDPFVD-EFIIIVKYMKEK- 58
AV++ G KG R RPL+ + PKP++ +A +P+I + + + I ++ + +E+
Sbjct: 8 AVIMVGGPTKGTRFRPLSFNTPKPLIPLAGQPMIHHPISACKKISNLAQIFLIGFYEERE 67
Query: 59 ---IIETLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEE---FFAINGDIYFEQEA 112
+ ++ +E P+ Y+ + + G+A A+Y +D I EE+ F +N D+
Sbjct: 68 FALYVSSISNELK-IPVRYLKEDKPHGSAGALYYFRDRIMEEKPSHVFLLNCDVCCSFP- 125
Query: 113 IRGLLHVYKKTKANAALVVKKF--DDLSQLG--MVKTEGGYVREIVEKPGN-VGGLANLG 167
++G+L +++ ++V K + SQ G + + + EKP V L N G
Sbjct: 126 LQGILDAHRRYGGIGTMLVIKVSAEAASQFGELIADPDTKELLHYTEKPETFVSDLINCG 185
Query: 168 IYIFNPDVFEFIERTQESER--------------GEYEITDTINLMISDGRKVAY-FEYS 212
+Y+F D+F IE R ++ D L G+K Y +E
Sbjct: 186 VYVFTSDIFNAIEEVYSQIRDTSSNYQSATRSVPADFVRLDQDILSPLAGKKQLYTYENK 245
Query: 213 GFWSDIGRPWDLLEVNEYILKTKLKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPV 272
FW I P L+ + L R T P + G IIG V
Sbjct: 246 DFWEQIKTPGKSLKCSALYLS-----QFRET--------SPHILASGDGTNRKPTIIGDV 292
Query: 273 KIGKNCRIGPNCFIRPYTSIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNL 332
I + ++ P I P SI N +G V + + II+D+ V +SI+G +++
Sbjct: 293 YIHPSVKLHPTAKIGPNVSISANVRVGPGVRLISCIILDDVEIKENAVVINSIIGWKSSI 352
Query: 333 GAG-------TITANLRHDNRTIKVEIK 353
G + ++ N+T+ V ++
Sbjct: 353 GEAVTVEDEVAVIGSIVLQNKTLNVSVQ 380
>gb|AAF73461.1|AF264025_12 (AF264025) putative dTDP-1-glucose synthase; AknY [Streptomyces
galilaeus]
Length = 291
Score = 87.0 bits (212), Expect = 4e-16
Identities = 74/255 (29%), Positives = 113/255 (44%), Gaps = 7/255 (2%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILE--NLDPFVDEFIIIVKYMKEK 58
MK ++LA G G RL P+T K +L V +KP+I Y L L + +I + E+
Sbjct: 1 MKGIILAGGSGTRLHPITVSVSKQLLPVGDKPMIYYPLSVLMLADIREILLICTERDLEQ 60
Query: 59 IIETLGDEFH-GKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLL 117
LGD G I Y Q G A A D++ +++ + GD F LL
Sbjct: 61 FRRLLGDGSQLGLRIDYAVQNRPAGLADAFVIGADHVGDDDVALVLGDNIFHGHHFYDLL 120
Query: 118 HVYKKTKANAALVVKKFDDLSQLGMVKTE-GGYVREIVEKPGNV-GGLANLGIYIFNPDV 175
L +D + G+ +T+ G + + EKP LA G+Y+++ +V
Sbjct: 121 QSNVHDVQGCVLFGYPVEDPERYGVGETDASGQLVSLEEKPLRPRSDLAITGLYLYDNEV 180
Query: 176 FEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGF-WSDIGRPWDLLEVNEYILKT 234
+ + + S RGE EITD ++ GR GF W D G P LL+ +Y+
Sbjct: 181 VDIAKNLRPSPRGELEITDVNRNYLARGRARLVDLGRGFAWLDAGTPESLLQATQYVRTL 240
Query: 235 KLKHDIR-GTVEEGA 248
+ + +R VEE A
Sbjct: 241 EERQGVRIACVEEVA 255
>gi|11497858 glucose-1-phosphate thymidylyltransferase (graD-1) [Archaeoglobus
fulgidus] >gi|7448175|pir||B69280 glucose-1-phosphate
thymidylyltransferase (graD-1) homolog - Archaeoglobus
fulgidus >gi|2650399|gb|AAB90991.1| (AE001089)
glucose-1-phosphate thymidylyltransferase (graD-1)
[Archaeoglobus fulgidus]
Length = 332
Score = 86.2 bits (210), Expect = 6e-16
Identities = 84/330 (25%), Positives = 148/330 (44%), Gaps = 28/330 (8%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPFVDEFIIIVKYMKEKII 60
MK +++A G RL P+T + KP+L V K I++++ E + F ++ E+
Sbjct: 1 MKVIIMAGGYATRLWPITKSKAKPLLPVGTKRIVDHVYEKVLKFNSPILLSTNKRFEEDF 60
Query: 61 ETLGDEFHGKPITYVSQVEEE--GTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLLH 118
+ + + + EEE G KA+ + I +++F + GD F E + ++
Sbjct: 61 RKWAEGKDVEVVVEDTMREEEKLGAVKALAQVVEGI-DDDFLVVAGDNIFSFE-LNPIVE 118
Query: 119 VYKKTKA--NAALVVKKFDDLSQLGMVKTEGGYVREIVEKPGN-VGGLANLGIYIFNPDV 175
+++K K+ A V ++ + G+ + EG VR EKP L + IY F ++
Sbjct: 119 LFRKKKSPVTALYDVGDYELAKRYGVAELEGEIVRRFYEKPEKPASTLVGIAIYTFPREI 178
Query: 176 FE-FIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKT 234
+ +E +ER + + D ++ + +G W D+G P +E ++ +
Sbjct: 179 ADLLVEYVGGNERSD-NLGDFLSYLCQKMDVYGCIFDNGNWYDVGNPDSYIEAFKFYTDS 237
Query: 235 KLKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGP-VKIGKNCRIGPNCF-------- 285
+ + V + A II PV I E VV G I+GP IG+ C I +
Sbjct: 238 FVHESVE--VAKAAKIIEPVVI-ERDVVIKGRSIVGPYAYIGEGCEIDSSDVSESVVFSK 294
Query: 286 -----IRPYTS-IGDNCHIGNAVEIKNSII 309
+R + S I D+C I N +E+ SII
Sbjct: 295 TVLKRVRLWRSIIDDDCEIRN-IELSGSII 323
>gb|AAC38757.1| (AF030373) glucose-1-phosphate thymidyl transferase [Streptococcus
pneumoniae] >gi|3818496|gb|AAC69538.1| (AF057294)
Cps23fO [Streptococcus pneumoniae]
Length = 289
Score = 85.8 bits (209), Expect = 8e-16
Identities = 71/238 (29%), Positives = 107/238 (44%), Gaps = 8/238 (3%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPFVDEFIIIVKYMKE--- 57
MK ++LA G G RL PLT K ++ V +KP+I Y L L I+I+ ++
Sbjct: 1 MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLAGIRDILIISTPQDLPR 60
Query: 58 -KIIETLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGL 116
K + G EF G ++Y Q +G A+A +++I ++ I GD + + +
Sbjct: 61 FKELLQDGSEF-GIKLSYAEQPSPDGLAQAFIIGEEFIGDDSVALILGDNIYHGPGLSTM 119
Query: 117 LHVYKKTKANAALVVKKFDDLSQLGMVK-TEGGYVREIVEKPGNV-GGLANLGIYIFNPD 174
L K + A + D + G+V+ E I EKP A G+Y ++ D
Sbjct: 120 LQKAAKKEKGATVFGYHVKDPERFGVVEFDENMNAISIEEKPEYPRSNYAVTGLYFYDND 179
Query: 175 VFEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGF-WSDIGRPWDLLEVNEYI 231
V E + + S RGE EITD + G GF W D G LLE ++YI
Sbjct: 180 VVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRGFAWLDTGTHESLLEASQYI 237
>gb|AAD10181.1| (AF026471) Cps2L [Streptococcus pneumoniae]
Length = 289
Score = 85.8 bits (209), Expect = 8e-16
Identities = 71/238 (29%), Positives = 108/238 (44%), Gaps = 8/238 (3%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPFVDEFIIIVKYMKE--- 57
MK ++LA G G RL PLT K ++ V +KP+I Y L L + I+I+ ++
Sbjct: 1 MKGIILAGGSGTRLYPLTRATSKQLMPVYDKPMIYYPLSTLMLAGIKDILIISTPQDLPR 60
Query: 58 -KIIETLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGL 116
K + G EF G ++Y Q +G A+A +D+I ++ I GD + + +
Sbjct: 61 FKDLLLDGSEF-GIRLSYAEQPSPDGLAQAFLIGEDFIGDDSVALILGDNIYHGPGLSKM 119
Query: 117 LHVYKKTKANAALVVKKFDDLSQLGMVK-TEGGYVREIVEKPG-NVGGLANLGIYIFNPD 174
L + A + + D + G+V+ E I EKP A G+Y ++ D
Sbjct: 120 LQKTVSKEKGATVFGYQVKDPERFGVVEFDENMNAISIEEKPECPRSNYAVTGLYFYDND 179
Query: 175 VFEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGF-WSDIGRPWDLLEVNEYI 231
V E + + S RGE EITD + G GF W D G LLE ++YI
Sbjct: 180 VVEIAKSIKPSARGELEITDVNKAYLDRGNLSVEVMGRGFAWLDTGTHESLLEASQYI 237
>gb|AAF58116.1| (AE003809) CG8207 gene product [Drosophila melanogaster]
Length = 448
Score = 85.8 bits (209), Expect = 8e-16
Identities = 91/378 (24%), Positives = 154/378 (40%), Gaps = 57/378 (15%)
Query: 1 MKAVVLAAG--KGERLRPLTDDRPKPILKVANKPIIEYILENLD--PFVDEFIIIVKYMK 56
+KAV+L G KG R RPL+ D PKP+ +A +P+I + +E P + E +II Y +
Sbjct: 2 LKAVILIGGPQKGTRFRPLSLDTPKPLFPLAGRPLIAHHIEACAQLPDIREILIIGYYPQ 61
Query: 57 EKIIETLGD-----EFHGKPITYVSQVEEEGTAKAIYSAKDYI---EEEEFFAINGDIYF 108
++ +GD I Y+ + GTA +Y +D I FF +NGD+
Sbjct: 62 TQMEGFVGDMQALYSSSNINIRYLQEFTALGTAGGMYHFRDQIRAGNPRAFFVLNGDVCA 121
Query: 109 EQEAIRGLLHVYKKTKANAALVVKKFDDLSQLGM------VKTEGGYVREIVEKPGN-VG 161
+ ++ L ++K A+A + + + Q + G V VEKP + V
Sbjct: 122 D-FPLQELCDFHEKRPASALVTIMSTEATRQQSLHYGCLVFDRSSGAVSHYVEKPSSYVS 180
Query: 162 GLANLGIYIFNPDVFE-----FIERTQE---------------SERGEYEITDTINLMIS 201
N G+Y+ + D+F F R QE E+G + + ++
Sbjct: 181 TFINCGVYVCSMDIFTVLAQIFHSRGQEYSCQAFCNGNGNGNGREQGHIKWEQEVLTPLA 240
Query: 202 DGRKVAYFEYSGFWSDIGRPWDLLEVNEYILKTKLKHDIRGTVEEGATIIPPVEIGEG-- 259
K+ +WS + + N + L K G ++ GEG
Sbjct: 241 GTDKLFAMPVPNWWSQLKTAGSAIYANRHYLGLYKKTHPERLANVG------IKRGEGDG 294
Query: 260 ---TVVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDNCHIGNAVEIKNSIIMDNSNAP 316
V Y+ + + +GPN I P +IG I ++ ++ + I+D++
Sbjct: 295 SLICTVHPDVYVHPSATVHHSAVLGPNVAIGPGVTIGPGVRIRESIVLEQAQILDHTLVL 354
Query: 317 HLNYVGDSIVGENTNLGA 334
H SIVG + +GA
Sbjct: 355 H------SIVGRGSTIGA 366
>pir||T39403 probable mannose-1-phosphate gaunyl transferase - fission yeast
(Schizosaccharomyces pombe) >gi|3080527|emb|CAA18655.1|
(AL022600) putative mannose-1-phosphate
guanyltransferase. [Schizosaccharomyces pombe]
Length = 414
Score = 85.8 bits (209), Expect = 8e-16
Identities = 100/392 (25%), Positives = 162/392 (40%), Gaps = 63/392 (16%)
Query: 3 AVVLAAG--KGERLRPLTDDRPKPILKVANKPIIEYILENLDPFVD-EFIIIVKYMKEKI 59
AV+L G +G R RPL+ D PKP+ K+ + +I + L L + + +V + E +
Sbjct: 5 AVILVGGPSRGTRFRPLSFDVPKPLFKIGGREMIYHHLAALSKIESVKDVFLVGFYDESV 64
Query: 60 IETLGDEFHG-----KPITYVSQVEEEGTAKAIYSAKDYI---EEEEFFAINGDIYFEQE 111
+ +E I Y+ + GT +Y +D I F ++ D+
Sbjct: 65 FKDFINEVASHFPSFNRIKYLREYNCLGTGGGLYHFRDQILKGHTSNVFVMHADVCCSFP 124
Query: 112 AIRGLLHVYKKTKANAALVVKKF--DDLSQLGMVKTEG--GYVREIVEKPGN-VGGLANL 166
++ LL+V+ + KA L+ K +D S G + E G V V+KP + + + +
Sbjct: 125 -LQELLNVHHEKKALVTLMATKVSKEDASNFGCLVEEPSTGRVLHYVDKPSSYLSNIISC 183
Query: 167 GIYIFNPDVFEFIERTQESERGEYEI----------------TDTINLMISDGRKVAY-F 209
GIYIF+ +F+ I++ E E E TD + + SD K Y +
Sbjct: 184 GIYIFDASIFDEIKKAYERRLEEVEKQLRSLDEGMEDYLSLETDVLAPLCSDSSKAIYAY 243
Query: 210 EYSGFWSDIGRPWDLLEVNEYILKTKLKHDIRGTV---EEGATIIPPVEIGEGTVVRSGS 266
FW I + N L+ K HD GT+ + A II PV I +V G+
Sbjct: 244 NTPEFWRQIKTAGSAVPANSLYLQ-KAYHD--GTLPKPDTEAEIIQPVFIHPNAIVSKGA 300
Query: 267 YIIGPVKIGKNCRIGPNCFIRPYTSIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIV 326
+IGPN SIG I + I+NSII ++ V SI+
Sbjct: 301 ------------KIGPN------VSIGARVRIEDGARIRNSIIQEDCEISANAVVLHSIL 342
Query: 327 GENTNLG-----AGTITANLRHDNRTIKVEIK 353
+ +G G+ T +H ++ +K
Sbjct: 343 SRHCKIGKWSRVEGSPTLPSQHSTTIMRNSVK 374
>gb|AAC44969.1| (U09239) glucose-1-phosphate thymidyl transferase [Streptococcus
pneumoniae]
Length = 289
Score = 85.8 bits (209), Expect = 8e-16
Identities = 71/238 (29%), Positives = 105/238 (43%), Gaps = 8/238 (3%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILEN--LDPFVDEFIIIVKYMKEK 58
MK ++LA G G RL PLT K ++ V +KP+I Y L L D II +
Sbjct: 1 MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLAGIRDILIISTPQDLHR 60
Query: 59 IIETL--GDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGL 116
E L G EF G ++Y Q +G A+A +++I ++ I GD + + +
Sbjct: 61 FQELLQDGSEF-GLKLSYAEQPSPDGLAQAFIIGEEFISDDSVALILGDNIYHGSGLSKM 119
Query: 117 LHVYKKTKANAALVVKKFDDLSQLGMVKTEGGY-VREIVEKPGNV-GGLANLGIYIFNPD 174
L ++ A + D + G+V+ + I EKP A G+Y ++ D
Sbjct: 120 LQKAASKESGATVFGYHVKDPERFGVVEFDQDMKAISIEEKPEQPRSNYAVTGLYFYDND 179
Query: 175 VFEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGF-WSDIGRPWDLLEVNEYI 231
V E + + S RGE EITD + G GF W D G LLE ++YI
Sbjct: 180 VVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRGFAWLDTGTHESLLEASQYI 237
>gb|AAD31799.1|AF128273_2 (AF128273) TDP-glucose synthase homolog [Streptomyces griseus]
Length = 289
Score = 85.0 bits (207), Expect = 1e-15
Identities = 73/253 (28%), Positives = 111/253 (43%), Gaps = 7/253 (2%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILE--NLDPFVDEFIIIVKYMKEK 58
MK ++LA G G RL+P+T K +L V +KP+I Y L L D I+ +
Sbjct: 1 MKGIILAGGHGTRLQPITFGVSKQLLPVYDKPMIYYPLSVLMLAGITDIQIVAAPDGLQG 60
Query: 59 IIETLGDEFH-GKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLL 117
LGD G ++Y Q + G A A ++D+I ++ + GD F +L
Sbjct: 61 FRRLLGDGSDLGLDLSYAEQDKPRGLADAFLVSEDHIGDDAVALVLGDNLFHGPGFSDIL 120
Query: 118 HVYKKTKANAALVVKKFDDLSQLGMVKTEG-GYVREIVEKPGNV-GGLANLGIYIFNPDV 175
A L D + G+ + +G G + + EKP LA G+Y ++ DV
Sbjct: 121 RRVALDLDGAVLFGYPVRDPERYGVGEVDGAGNLTALEEKPARPRSNLAITGLYFYDNDV 180
Query: 176 FEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGF-WSDIGRPWDLLEVNEYILKT 234
E + SERGE EITD + G+ GF W D G L++ +Y+
Sbjct: 181 VEIARSLRPSERGELEITDVNRRYLERGKAALVQLGRGFVWLDTGTHDALIDAGQYVQLL 240
Query: 235 KLKHDIR-GTVEE 246
+ + +R VEE
Sbjct: 241 EHRQGVRIACVEE 253
>emb|CAB95915.1| (AL359989) putative UDP-N-acetylglucosamine pyrophosphorylase,
partial CDS [Streptomyces coelicolor A3(2)]
Length = 343
Score = 84.7 bits (206), Expect = 2e-15
Identities = 69/277 (24%), Positives = 116/277 (40%), Gaps = 65/277 (23%)
Query: 181 RTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEY--ILKTKLKH 238
RT S+ EY +TD + ++ G +V +G +I + +++ E IL +L
Sbjct: 58 RTDNSQGEEY-LTDVLGILREAGHRVGA-SVAGDHREIAGINNRVQLAEARRILNDRL-- 113
Query: 239 DIRGTVEEGATIIPP--------VEIGEGTVVRSGSYIIGPVKIGKNCRIGPN------- 283
+ G + G T++ P V + VV G+ + G + + C +GPN
Sbjct: 114 -LTGAMLAGVTVVDPATTWVDVTVTFEQDVVVHPGTQLHGTTHLAEGCEVGPNTRLTDTR 172
Query: 284 --------------------------CFIRPYTSIGDNCHIGNAVEIKNSIIMDNSNAPH 317
++RP T +G IG VE KNS I + + PH
Sbjct: 173 VEAGARVDNTVANGAHVGPQASVGPYAYLRPGTRLGLKSKIGTFVEAKNSSIGEGTKVPH 232
Query: 318 LNYVGDSIVGENTNLGAGTITANLRHDNRTIKVEIKGKLEDSGRRKLGAIIGHNVKTGIN 377
L+Y+GD+ VG+ TN+GA ++ N G+ K IG + +TG +
Sbjct: 233 LSYMGDATVGDFTNIGAASVFVNY-----------------DGQDKHHTTIGSHCRTGSD 275
Query: 378 VTIYPGRKIGSGALVGPGVIVDKNIPPNVLVVAKQEK 414
+G GA G ++ K++PP L VA+ ++
Sbjct: 276 NMFVAPVTVGDGAYTAAGSVITKDVPPGSLAVARGQQ 312
>sp|O08326|GLGC_BACST GLUCOSE-1-PHOSPHATE ADENYLYLTRANSFERASE (ADP-GLUCOSE SYNTHASE)
(ADP-GLUCOSE PYROPHOSPHORYLASE)
>gi|1944411|dbj|BAA19589.1| (D87026) subunit of
ADP-glucose pyrophosphorylase [Bacillus
stearothermophilus]
Length = 387
Score = 84.7 bits (206), Expect = 2e-15
Identities = 86/354 (24%), Positives = 162/354 (45%), Gaps = 45/354 (12%)
Query: 3 AVVLAAGKGERLRPLTDDRPKPILKVANK-PIIEYILENL-DPFVDEFIIIVKYMKEKII 60
A++LA G+G RLR LT + KP + K II++ L N + +D ++ +Y +
Sbjct: 7 AMLLAGGQGSRLRSLTTNIAKPAVPFGGKYRIIDFTLSNCTNSGIDTVGVLTQYQPLLLH 66
Query: 61 ETLG-------DEFHG-----KPITYVSQVE-EEGTAKAIYSAKDYIEE---EEFFAING 104
+G D +G P + S V+ EGTA A+Y +YIE+ + ++G
Sbjct: 67 SYIGIGSAWDLDRRNGGVTVLPPYSVSSGVKWYEGTANAVYQNINYIEQYNPDYVLVLSG 126
Query: 105 DIYFEQEAIRGL-LHVYKKTKANAALVVKKFDDLSQLGMVKT-EGGYVREIVEKPGNV-G 161
D ++ + L H+ K+ +++ +++ S+ G++ T E + E EKP
Sbjct: 127 DHIYKMDYQHMLDYHIAKQADVTISVIEVPWEEASRFGIMNTNEEMEIVEFAEKPAEPKS 186
Query: 162 GLANLGIYIFN-PDVFEFIERTQESERGEYEI-TDTINLMISDGRKVAYFEYSGFWSDIG 219
LA++GIYIFN P + ++++ + ++ D I +++ + ++ + + G+W D+G
Sbjct: 187 NLASMGIYIFNWPLLKQYLQIDNANPHSSHDFGKDVIPMLLREKKRPFAYPFEGYWKDVG 246
Query: 220 RPWDLLEVNEYILKTKLKHD-------------------IRGTVEEGATIIPPVEIGEGT 260
L E N +L + D I E +++ + EGT
Sbjct: 247 TVKSLWEANMDLLDENNELDLFDRSWRIYSVNPNQPPQYISPEAEVSDSLVNEGCVVEGT 306
Query: 261 VVRSGSYIIGPVKIGKNCRIGPNCFIRPYTSIGDNCHIGNAVEIKNSIIMDNSN 314
V R S + V+IGK + I P ++ + ++ A+ +SII +S+
Sbjct: 307 VER--SVLFQGVRIGKGA-VVKESVIMPGAAVSEGAYVERAIVTPDSIIPPHSS 357
>gb|AAD22456.1|AF116284_2 (AF116284) unknown [Pseudomonas aeruginosa]
Length = 224
Score = 84.7 bits (206), Expect = 2e-15
Identities = 73/233 (31%), Positives = 112/233 (47%), Gaps = 15/233 (6%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIE-YILENLDPFVDEFIIIVKYMKEKI 59
MKA++LAAG+GER+RP T PKP+++ A P+IE +L VD+++I ++ E+I
Sbjct: 1 MKAMILAAGRGERMRPTTLHTPKPLIEAAGVPLIERQLLALRQAGVDDWVINHAWLGEQI 60
Query: 60 IETLGDEFH-GKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLLH 118
LGD G I Y + E T I+ A + E+ F +NGD++ + + R LH
Sbjct: 61 EAYLGDGSRLGGRIAYSPEGEPLETGGGIFRALPLLGEQPFLLLNGDVWSDFDYSR--LH 118
Query: 119 VYKKTKANAALVVKKFDDLSQLGMVKTEGGYVREIVEKPGNVGGLANLGIYIFNPDVFEF 178
+ A+ LV + GG V E E GN L GI + +P +FE
Sbjct: 119 LADGDLAHLVLVDNPAHHPAG-DFHLDAGGRVGETREAGGN---LTYSGIAVLHPALFE- 173
Query: 179 IERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYI 231
+ G +++ + I+ GR V+ Y G W D+G L EV +
Sbjct: 174 -----GCQPGAFKLAPLLRKAIAAGR-VSGEHYRGQWVDVGTHERLAEVERLL 220
>gb|AAC68682.1| (AF079762) alpha-D-glucose-1-phosphate thymidylyltransferase
[Streptomyces venezuelae]
Length = 292
Score = 84.3 bits (205), Expect = 2e-15
Identities = 74/237 (31%), Positives = 103/237 (43%), Gaps = 6/237 (2%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILE--NLDPFVDEFIIIVKYMKEK 58
MK +VLA G G RL P T K IL V NKP+I Y L L + II E
Sbjct: 1 MKGIVLAGGSGTRLHPATSVISKQILPVYNKPMIYYPLSVLMLGGIREIQIISTPQHIEL 60
Query: 59 IIETLGDEFH-GKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLL 117
LG+ H G + Y Q E G A A+ ++I ++ I GD F + LL
Sbjct: 61 FQSLLGNGRHLGIELDYAVQKEPAGIADALLVGAEHIGDDTCALILGDNIFHGPGLYTLL 120
Query: 118 HVYKKTKANAALVVKKFDDLSQLGMVKTEG-GYVREIVEKPGNV-GGLANLGIYIFNPDV 175
L D + G+ + + G + ++VEKP LA G+Y+++ DV
Sbjct: 121 RDSIARLDGCVLFGYPVKDPERYGVAEVDATGRLTDLVEKPVKPRSNLAVTGLYLYDNDV 180
Query: 176 FEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGF-WSDIGRPWDLLEVNEYI 231
+ + + S RGE EITD + + GR GF W D G LL +Y+
Sbjct: 181 VDIAKNIRPSPRGELEITDVNRVYLERGRAELVNLGRGFAWLDTGTHDSLLRAAQYV 237
>gb|AAF01820.1|AF187532_16 (AF187532) putative dTDP-glucose synthase [Streptomyces nogalater]
Length = 293
Score = 84.3 bits (205), Expect = 2e-15
Identities = 73/255 (28%), Positives = 109/255 (42%), Gaps = 7/255 (2%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILE--NLDPFVDEFIIIVKYMKEK 58
MK ++LA G G RL P T K +L V +KP+I Y L L D II + +
Sbjct: 1 MKGIILAGGTGSRLHPTTLAVSKQLLPVGDKPMIYYPLSVLMLAGVTDILIISTPHELPR 60
Query: 59 IIETLGDEFH-GKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLL 117
+ GD G + Y Q + G A+A D++ + GD F + +G+L
Sbjct: 61 MRRLFGDGAQLGLRLAYAEQEKPRGIAEAFLIGADHVGSDAVALALGDNIFHGSSFQGVL 120
Query: 118 HVYKKTKANAALVVKKFDDLSQLGMVKTE-GGYVREIVEKPGNV-GGLANLGIYIFNPDV 175
+ L D + G+ + G + I EKP A G+Y ++ +V
Sbjct: 121 RKEAEELDGCVLFGYPVKDPQRYGVGEANASGRLVSIEEKPVRPRSNRAITGLYFYDNEV 180
Query: 176 FEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGF-WSDIGRPWDLLEVNEYILKT 234
+ R + S RGE EITD + GR GF W D G P LL+ ++Y+
Sbjct: 181 VDIARRLRPSARGELEITDINRTYMERGRARLVDLGRGFAWLDTGTPESLLQASQYVSAL 240
Query: 235 KLKHDIR-GTVEEGA 248
+ + IR +EE A
Sbjct: 241 EERQGIRIACIEEVA 255
>emb|CAB65204.1| (AJ007311) RmlA protein [Legionella pneumophila]
Length = 291
Score = 83.9 bits (204), Expect = 3e-15
Identities = 77/255 (30%), Positives = 115/255 (44%), Gaps = 11/255 (4%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLD-PFVDEFIIIVKYMKEKI 59
MK ++LA G G RL PLT K ++ V +KP+I Y + L + E +II +
Sbjct: 1 MKGIILAGGFGTRLYPLTKSISKHMIPVYDKPMIYYAISTLMLANIREILIISTEEHLPL 60
Query: 60 IETL---GDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGL 116
+ L G ++ G Y+ Q E G A+A + +I + + GD + L
Sbjct: 61 YQNLLSDGSQW-GISFAYLVQNEPRGIAEAFILGEKFIGNDSVCLVLGDNIHQGRGFSEL 119
Query: 117 LHVYKKTKANAALVVKKFDDLSQ-LGMVK-TEGGYVREIVEKPGN-VGGLANLGIYIFNP 173
L K+K N A V + D Q G+V+ E V IVEKP A G+Y ++
Sbjct: 120 LQ-NAKSKLNGATVFAYYVDKPQAYGVVEFNEKQQVLSIVEKPAQPKSNYAVTGLYFYDN 178
Query: 174 DVFEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGF-WSDIGRPWDLLEVNEYIL 232
V E + + S RGE EITD + + + GF W D+G P LL + YI
Sbjct: 179 QVIEIAKSLKPSGRGELEITDINQFYLYENKLDVQILGRGFVWLDMGTPETLLSASNYIC 238
Query: 233 KTKLKHDIR-GTVEE 246
+ + ++ G EE
Sbjct: 239 TIEQRQGLKIGCPEE 253
>emb|CAB89282.1| (AJ277601) glucose-1-phosphate adenylyltransferase [Clostridium
cellulolyticum]
Length = 426
Score = 83.9 bits (204), Expect = 3e-15
Identities = 110/445 (24%), Positives = 186/445 (41%), Gaps = 70/445 (15%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANK-PIIEYILENL-DPFVDEFIIIVKYMKEK 58
M A++LA G+G RL LT + KP + K II++ L N + +D ++ +Y K
Sbjct: 6 MIAMLLAGGQGSRLGVLTKNVAKPAVLYGGKYRIIDFSLSNCTNSGIDTVGVLTQYQPLK 65
Query: 59 IIETLGDEFHGKP---------ITYVSQVEE-------EGTAKAIYSAKDYIEEEE---F 99
+ +G GKP +T +S + +GTA A+Y YI++
Sbjct: 66 LNAHIGI---GKPWDMDRIEGGVTILSPYLKAEMGEWFKGTANAVYQNIQYIDKYSPHYV 122
Query: 100 FAINGDIYFEQEAIRGLLHVYKKTKANAALVVKK--FDDLSQLGMVKT-EGGYVREIVEK 156
++GD ++ + + +L +K+ A+A + V +++ S+ G++ E G + E EK
Sbjct: 123 IILSGDHIYKMDYSK-MLDFHKENHADATISVINVPYEEASRYGIMNCHENGKIYEFEEK 181
Query: 157 PGNVGG-LANLGIYIFNPDVF-EFIERTQESERGEYEI-TDTINLMISDGRKVAYFEYSG 213
P N LA++G+YIF E++ + E + + I M+ DG+ + ++YSG
Sbjct: 182 PKNPKSTLASMGVYIFTWSTLREYLIKDNECSDSVNDFGKNIIPAMLGDGKSMWAYQYSG 241
Query: 214 FWSDIGRPWDLLEVNEYILKTKLKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVK 273
+W D+G E + D+ V + P I V+ YI
Sbjct: 242 YWRDVGTIQAFWESS---------MDLVSRVPQFNLFDPEWRIYTPNPVKPAHYIASSAC 292
Query: 274 IGKNCRIGPNCFIRP---YTSIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDS------ 324
+ K+ I C + + + +I I++SIIM NS Y+ S
Sbjct: 293 VKKSI-IAEGCSVHGTVINSILFPGAYIEEGAVIQDSIIMSNSRVCKNAYINRSIISEQA 351
Query: 325 IVGENTNLGAGTITANLRHDNRTIKVEIKGKLEDSGRRKLG--------AIIGHNV--KT 374
I+GE LG G N E K + DSG +G +IG NV
Sbjct: 352 IIGEKARLGEGPDVPN----------EYKPGIYDSGITVVGEKSSIPADPVIGKNVMIDI 401
Query: 375 GINVTIYPGRKIGSGALVGPGVIVD 399
G + + + SG V G + +
Sbjct: 402 GASAVDFTSLNVQSGKSVFKGGVAE 426
>emb|CAC01394.1| (AJ131360) glucose-1-phosphate thymidyltransferase [Campylobacter
jejuni]
Length = 307
Score = 83.9 bits (204), Expect = 3e-15
Identities = 69/245 (28%), Positives = 112/245 (45%), Gaps = 8/245 (3%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPFVDEFIIIVKYMK--EK 58
MK ++LA G G RL P T K +L + +KP+I Y + L + ++I+ K ++
Sbjct: 16 MKGIILAGGSGTRLYPSTLTLCKQLLPIYDKPMIYYPMSVLMLAKIKEVLIISTPKDIDR 75
Query: 59 IIETLGD-EFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLL 117
E D F G I Y Q EG A+ + A+D+I+ ++ I GD F + +L
Sbjct: 76 FKELFKDGSFLGMQIQYKIQERPEGLAQGLILAQDFIQNDDIALILGDNIFYGQGFSDIL 135
Query: 118 HVYKK--TKANAALVVKKFDDLSQLGMVK-TEGGYVREIVEKPGN-VGGLANLGIYIFNP 173
K K A++ D + G+V+ + G V + EKP N G+Y +N
Sbjct: 136 ENAKDDLKKGFASIFSYHVKDPERFGVVEMDQNGNVLSLEEKPKNPKSNHVATGLYFYNN 195
Query: 174 DVFEFIERTQESERGEYEITD-TINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYIL 232
D + + + S RGE EITD I + + K + W D G L+E + ++
Sbjct: 196 DAIDIAKNVKPSARGELEITDVNIEYLRLNKLKSQHLGRGFAWIDTGTHDSLIEASSFVQ 255
Query: 233 KTKLK 237
+L+
Sbjct: 256 TIELR 260
>emb|CAB88923.1| (AL353862) putative nucleotide phosphorylase [Streptomyces
coelicolor A3(2)]
Length = 360
Score = 83.5 bits (203), Expect = 4e-15
Identities = 88/351 (25%), Positives = 149/351 (42%), Gaps = 38/351 (10%)
Query: 2 KAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENLDPF-VDEFIIIVKYMKEKII 60
+A++L GKG RLRPLT + PKP+++ A P + + L V+ ++ Y+ E
Sbjct: 3 EAILLVGGKGTRLRPLTVNTPKPMVRAAGVPFLTHQLARAKAAGVEHIVLATSYLAEVFE 62
Query: 61 ETLGD-EFHGKPITYVSQVEEEGTAKAIYSAKDYIE---EEEFFAINGDIYFEQEAIRGL 116
GD G + YV++ E GT AI + + +E NGDI + I L
Sbjct: 63 PYFGDGSTLGLHLEYVTEEEPLGTGGAIRNVASRLHSGPDEPVLIFNGDILTGLD-IGAL 121
Query: 117 LHVYKKTKANAALVVKKFDDLSQLGMVKTEG-GYVREIVEKPGN----VGGLANLGIYIF 171
+ ++ T A+ +L + + D G+V T+ G V +EKP V N G Y+F
Sbjct: 122 VRTHETTGADVSLHLTQVTDPRAYGLVPTDDTGRVLAFLEKPQTPEEIVTDQINAGAYVF 181
Query: 172 NPDVFEFIE--RTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVN- 228
V + I R ER +T +++ G + S +W D+G P + +
Sbjct: 182 RRSVIDTIPAGRPVSVER------ETFPELLATGAHLQGMVDSTYWLDLGTPAAFVRGSA 235
Query: 229 EYILKTKLKHDIRG-----TVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPN 283
+ +L + G V A + P ++ GTVV G+++ ++ I P
Sbjct: 236 DLVLGRAPSPAVPGRCGDRLVLPTAQVAPDAKLTGGTVVGEGAFVAEGARV-FGSTILPG 294
Query: 284 CFIRPYTSIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGA 334
I P I D S+I + + + D+++G+ +GA
Sbjct: 295 AVIEPGAVITD------------SLIGTRARVGTRSVLADTVIGDGAVIGA 333
>gb|AAD38517.1|AF135422_1 (AF135422) GDP-mannose pyrophosphorylase A [Homo sapiens]
Length = 399
Score = 82.7 bits (201), Expect = 7e-15
Identities = 83/365 (22%), Positives = 151/365 (40%), Gaps = 50/365 (13%)
Query: 1 MKAVVLAAG--KGERLRPLTDDRPKPILKVANKPIIEYILENLD--PFVDEFIIIVKYMK 56
+KAV+L G KG R RPL+ + PKP+ VA P+I++ +E P + E ++I Y
Sbjct: 2 LKAVILIGGPQKGTRFRPLSFEVPKPLFPVAGVPMIQHHIEACAQVPGMQEILLIGFYQP 61
Query: 57 EK----IIETLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYI---EEEEFFAINGDIYFE 109
++ +E EF+ P+ Y+ + GT +Y +D I E FF +N D+ +
Sbjct: 62 DEPLTQFLEAAQQEFN-LPVRYLQEFAPLGTGGGLYHFRDQILAGSPEAFFVLNADVCSD 120
Query: 110 QEAIRGLLHVYKKTKANAALVVKKFDDLSQLG----MVKTEGGYVREIVEKPGN-VGGLA 164
+ +L +++ + L+ + L + + V VEKP + +
Sbjct: 121 FP-LSAMLEAHRRQRHPFLLLGTTANRTQSLNYGCIVENPQTHEVLHYVEKPSTFISDII 179
Query: 165 NLGIYIFNPDVFEFIERTQESERGEYEITDTINLMISDGR---------------KVAYF 209
N GIY+F+P+ + + + + + ++ D+ L G ++
Sbjct: 180 NCGIYLFSPEALKPLRDVFQRNQQDGQLEDSPGLWPGAGTIRLEQDVFSALAGQGQIYVH 239
Query: 210 EYSGFWSDIGRPWDLLEVNE-YILKTKLKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYI 268
G WS I L + Y+ + + H P + + T G +I
Sbjct: 240 LTDGIWSQIKSAGSALYASRLYLSRYQDTH--------------PERLAKHTP--GGPWI 283
Query: 269 IGPVKIGKNCRIGPNCFIRPYTSIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGE 328
G V I ++ P+ + P SIG +G V ++ SI++ + V IVG
Sbjct: 284 RGNVYIHPTAKVAPSAVLGPNVSIGKGVTVGEGVRLRESIVLHGATLQEHTCVLHCIVGW 343
Query: 329 NTNLG 333
+ +G
Sbjct: 344 GSTVG 348
>pir||D83570 probable nucleotidyl transferase PA0597 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9946470|gb|AAG03986.1|AE004496_2 (AE004496) probable
nucleotidyl transferase [Pseudomonas aeruginosa]
Length = 224
Score = 82.7 bits (201), Expect = 7e-15
Identities = 72/233 (30%), Positives = 112/233 (47%), Gaps = 15/233 (6%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIE-YILENLDPFVDEFIIIVKYMKEKI 59
MKA++LAAG+GER+RP T PKP+++ A P+IE +L VD+++I ++ E+I
Sbjct: 1 MKAMILAAGRGERMRPTTLHTPKPLIEAAGVPLIERQLLALRQAGVDDWVINHAWLGEQI 60
Query: 60 IETLGDEFH-GKPITYVSQVEEEGTAKAIYSAKDYIEEEEFFAINGDIYFEQEAIRGLLH 118
LGD G I Y + E T I+ A + E+ F +NGD++ + + R LH
Sbjct: 61 EAYLGDGSRLGGRIAYSPEGEPLETGGGIFRALPLLGEQPFLLLNGDVWSDFDYSR--LH 118
Query: 119 VYKKTKANAALVVKKFDDLSQLGMVKTEGGYVREIVEKPGNVGGLANLGIYIFNPDVFEF 178
+ A+ LV + GG V E E GN L GI + +P +FE
Sbjct: 119 LADGDLAHLVLVDNPAHHPAG-DFHLDAGGRVGETREAGGN---LTYSGIAVLHPALFE- 173
Query: 179 IERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLEVNEYI 231
+ G +++ + I+ GR V+ + G W D+G L EV +
Sbjct: 174 -----GCQPGAFKLAPLLRKAIAAGR-VSGEHHRGQWVDVGTHERLAEVERLL 220
>pir||G64763 hypothetical protein b0359 - Escherichia coli
>gi|1786556|gb|AAC73462.1| (AE000143) putative
transferase [Escherichia coli K12]
Length = 147
Score = 80.4 bits (195), Expect = 4e-14
Identities = 45/119 (37%), Positives = 63/119 (52%)
Query: 285 FIRPYTSIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTITANLRHD 344
FIRP T I + IG A EIKN++I + ++ DS+V LGA T+N R D
Sbjct: 14 FIRPGTIISNGVKIGFATEIKNAVIEAEATIGPQCFIADSVVANQAYLGAQVRTSNHRLD 73
Query: 345 NRTIKVEIKGKLEDSGRRKLGAIIGHNVKTGINVTIYPGRKIGSGALVGPGVIVDKNIP 403
+ + V + +G KLG IG + G+ V I PGR I +GP VIV++N+P
Sbjct: 74 EQPVSVRTPEGIIATGCDKLGCYIGQRSRLGVQVIILPGRIISPNTQLGPRVIVERNLP 132
>gb|AAC46169.1| (AF017435) glmU-like gene product [Methylobacterium extorquens]
Length = 342
Score = 74.1 bits (179), Expect = 3e-12
Identities = 82/346 (23%), Positives = 148/346 (42%), Gaps = 33/346 (9%)
Query: 1 MKAVVLAAGKGERLRPLTDDRPKPILKVANKPIIEYILENL-DPFVDEFIIIVKYMKEKI 59
+ A+VLAAGKG R+R DRPK + +AN+ ++ ++L + + ++V+ +E +
Sbjct: 12 LHAIVLAAGKGTRMR---SDRPKVLHALANRSMLGHVLAAVQEAGAARLAVVVEPGREDV 68
Query: 60 IETLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEE-EEFFAINGDIYFEQEAIRGLLH 118
+ + G I Q E GTA A+ +A+ +E ++ GD L
Sbjct: 69 VREIERLAPGAGIH--PQAERLGTAHAVLAARASLEGGQDVIVAFGDTPLVTAETYARLR 126
Query: 119 VYKKTKANAALVVKKFDDLSQLGMVKTEGGYVREIVEKPG-----NVGGLANLGIYIFN- 172
+ A A++ + D + G V TEGG V I E+ L+N G+ +
Sbjct: 127 APLREGAAVAVLAFEAADPTGYGRVLTEGGRVLAIREEKDASQEERAVRLSNAGLMALSG 186
Query: 173 PDVFEFIERT-QESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRPWDLLE---VN 228
+ER ++ EY +TD + L DG VA P D E VN
Sbjct: 187 AHALSLLERIGNDNANREYYLTDAVALAAGDGLSVAVV-----------PVDEAEAQGVN 235
Query: 229 EYILKTKLKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRIGPNCFIRP 288
+ + ++ + I+ + A + + R G + +G++ + P+C P
Sbjct: 236 DRVQLSQAEPRIQARLRRAAQLGG----ADADRARDGVFFSVDTILGRDVVVEPHCVFGP 291
Query: 289 YTSIGDNCHIGNAVEIKNSIIMDNSN-APHLNYVGDSIVGENTNLG 333
IGD C I + ++ +M+ ++ PH+ G +++ +LG
Sbjct: 292 GVVIGDGCTIRAFSHLHDARLMEGADIGPHVRLRGGAVLEAGVHLG 337
>pir||B72403 glucose-1-phosphate adenylyltransferase - Thermotoga maritima
(strain MSB8) >gi|4980738|gb|AAD35331.1|AE001707_18
(AE001707) glucose-1-phosphate adenylyltransferase
[Thermotoga maritima]
Length = 423
Score = 74.1 bits (179), Expect = 3e-12
Identities = 97/428 (22%), Positives = 180/428 (41%), Gaps = 65/428 (15%)
Query: 3 AVVLAAGKGERLRPLTDDRPKPILKVANK-PIIEYILEN-LDPFVDEFIIIVKYMKEKII 60
A++LA G+G RL LT+ KP + K +I++ L N ++ + ++ +Y +
Sbjct: 6 AMILAGGQGTRLGVLTERIAKPAVPFGGKYRLIDFTLSNCVNSGIYRVGVLTQYRPHVLS 65
Query: 61 ETLGDEFHGKPIT-------------YVSQVEEE---GTAKAIYSAKDYIEEEE---FFA 101
+ +G G+P YV + E + GTA A+Y +++EE +
Sbjct: 66 KHIGI---GRPWDLDRKDGGVEILPPYVGRHESDWYKGTANAVYQNLEFLEENDAELVLI 122
Query: 102 INGDIYFEQEAIRGLL--HVYKKTKANAALVVKKFDDLSQLGMVKTE-GGYVREIVEKPG 158
++GD + L+ H+ K+ A + ++ S+ G++ T+ G + + EKP
Sbjct: 123 LSGDHVYAMN-YNDLIDYHLLKEADGTIACMEVPIEEASRFGIMITDVDGRIVDFEEKPA 181
Query: 159 NV-GGLANLGIYIFNPDVFEFIERTQESERGEYEIT-----DTINLMISDGRKVAY-FEY 211
LA+LGIY+FN +EF+++ + + + D I ++ + Y F +
Sbjct: 182 KPRSNLASLGIYVFN---YEFLKKVLIEDENDPNSSHDFGKDVIPRILRENLGSLYAFRF 238
Query: 212 SGFWSDIGRPWDLLEVN-EYILKTKL--KHDIRGTVEEGATIIPPVEIGEGTVVRSGSYI 268
G+W D+G E N E +L +D +PP + G+ V +
Sbjct: 239 DGYWRDVGTLRSYWEANLELVLPVPPFNLYDPNWRFFTHTEEMPPAYVAPGSKVSTSL-- 296
Query: 269 IGPVKIGKNCRIGPNCFIRPYTSIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGE 328
+ + + N F + I IG +KNS+IM + Y+ + I+ E
Sbjct: 297 -----VSEGAEVYGNVF---NSVIFQGVKIGRGTVVKNSVIMTRTEIGENCYLENVIIAE 348
Query: 329 NTNLGAGTITANLRHDNRTIKVEIKGKLEDSGRRKLGAIIGHNVKTGINVTIYPGRKIGS 388
N +G +N+R + + + KL+ L ++ G+N I IG
Sbjct: 349 NVKIG-----SNVR---MGVGEDAESKLDPKVYSGLLTVV------GMNSVIPDDMVIGK 394
Query: 389 GALVGPGV 396
++G GV
Sbjct: 395 NCVIGIGV 402
>gb|AAD55285.1|AC008263_16 (AC008263) Similar to gb|AF135422 GDP-mannose pyrophosphorylase A
(GMPPA) from Homo sapiens. ESTs gb|AA712990, gb|N65247,
gb|N38149, gb|T04179, gb|Z38092, gb|T76473, gb|N96403,
gb|AA394551 and gb|AA728527 come from this gene.
[Arabidopsis thaliana]
Length = 411
Score = 73.0 bits (176), Expect = 6e-12
Identities = 102/453 (22%), Positives = 184/453 (40%), Gaps = 88/453 (19%)
Query: 3 AVVLAAG--KGERLRPLTDDRPKPILKVANKPIIEYILENLD--PFVDEFIIIVKYMKEK 58
AV++ G KG R RPL+ + PKP+ +A +P++ + + P + + ++ Y + +
Sbjct: 7 AVIMVGGPTKGTRFRPLSLNIPKPLFPIAGQPMVHHPISACKRIPNLAQIYLVGFYEERE 66
Query: 59 I---IETLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEE---FFAINGDIYFEQEA 112
+ + +E P+ Y+ + + G+A +Y ++ I E+ F +N D+
Sbjct: 67 FALYVSAISNELK-VPVRYLREDKPHGSAGGLYHFRNLIMEDSPSHIFLLNCDVCCSFPL 125
Query: 113 IRGLLHVYKKTKANAALVVKKF--DDLSQLGMVKTEG--GYVREIVEKPGN-VGGLANLG 167
+ +L ++ L+V K + SQ G + + + EKP V N G
Sbjct: 126 PK-MLEAHRGYGGIGTLLVIKVSPESASQFGELVADPVTNELLHYTEKPETFVSDRINCG 184
Query: 168 IYIFNPDVFEFIE--RTQESERGEYEI--------------TDTINL---MISD--GRKV 206
+Y+F P++F I TQ +R + TD + L ++S G+K
Sbjct: 185 VYVFTPEIFNAIGDVSTQRKDRATLKRVSSFEALQPATRIPTDFVRLDQDILSPLAGKKR 244
Query: 207 AY-FEYSGFWSDIGRPWDLLEVNEYILKTKLKHDIRGTVEEGATIIPPVEIGEGTVVRSG 265
Y +E FW I P L + L + P + G RS
Sbjct: 245 LYTYETMDFWEQIKSPGMSLRCSGLYLSQ-------------FRLTSPQLLASGDGTRS- 290
Query: 266 SYIIGPVKIGKNCRIGPNCFIRPYTSIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSI 325
+ +IG V I + ++ P I P SI N +G V + + II+D+ V ++I
Sbjct: 291 AIVIGDVYIHPSAKVHPTAKIGPNVSISANARVGPGVRLMSCIILDDVEIMENAVVTNAI 350
Query: 326 VGENTNLGAGTITANLRHDNRTIKVEIKGKLEDSGRRKLGAIIGHNVKTGINVTIYPGRK 385
VG +++G R +V+ +G +N K G+ +
Sbjct: 351 VGWKSSIG------------RWSRVQAEGV--------------YNSKLGVTI------- 377
Query: 386 IGSGALVGPGVIVDKNI--PPNVLVVAKQEKIV 416
+G V V+V +I P L V+ Q++I+
Sbjct: 378 LGDSVAVEDEVVVTSSIVLPNKTLNVSVQDEII 410
>gb|AAF21085.1|AC013258_23 (AC013258) putative GDP-mannose pyrophosphorylase; 64911-67597
[Arabidopsis thaliana]
Length = 415
Score = 73.0 bits (176), Expect = 6e-12
Identities = 102/453 (22%), Positives = 184/453 (40%), Gaps = 88/453 (19%)
Query: 3 AVVLAAG--KGERLRPLTDDRPKPILKVANKPIIEYILENLD--PFVDEFIIIVKYMKEK 58
AV++ G KG R RPL+ + PKP+ +A +P++ + + P + + ++ Y + +
Sbjct: 11 AVIMVGGPTKGTRFRPLSLNIPKPLFPIAGQPMVHHPISACKRIPNLAQIYLVGFYEERE 70
Query: 59 I---IETLGDEFHGKPITYVSQVEEEGTAKAIYSAKDYIEEEE---FFAINGDIYFEQEA 112
+ + +E P+ Y+ + + G+A +Y ++ I E+ F +N D+
Sbjct: 71 FALYVSAISNELK-VPVRYLREDKPHGSAGGLYHFRNLIMEDSPSHIFLLNCDVCCSFPL 129
Query: 113 IRGLLHVYKKTKANAALVVKKF--DDLSQLGMVKTEG--GYVREIVEKPGN-VGGLANLG 167
+ +L ++ L+V K + SQ G + + + EKP V N G
Sbjct: 130 PK-MLEAHRGYGGIGTLLVIKVSPESASQFGELVADPVTNELLHYTEKPETFVSDRINCG 188
Query: 168 IYIFNPDVFEFIE--RTQESERGEYEI--------------TDTINL---MISD--GRKV 206
+Y+F P++F I TQ +R + TD + L ++S G+K
Sbjct: 189 VYVFTPEIFNAIGDVSTQRKDRATLKRVSSFEALQPATRIPTDFVRLDQDILSPLAGKKR 248
Query: 207 AY-FEYSGFWSDIGRPWDLLEVNEYILKTKLKHDIRGTVEEGATIIPPVEIGEGTVVRSG 265
Y +E FW I P L + L + P + G RS
Sbjct: 249 LYTYETMDFWEQIKSPGMSLRCSGLYLSQ-------------FRLTSPQLLASGDGTRS- 294
Query: 266 SYIIGPVKIGKNCRIGPNCFIRPYTSIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSI 325
+ +IG V I + ++ P I P SI N +G V + + II+D+ V ++I
Sbjct: 295 AIVIGDVYIHPSAKVHPTAKIGPNVSISANARVGPGVRLMSCIILDDVEIMENAVVTNAI 354
Query: 326 VGENTNLGAGTITANLRHDNRTIKVEIKGKLEDSGRRKLGAIIGHNVKTGINVTIYPGRK 385
VG +++G R +V+ +G +N K G+ +
Sbjct: 355 VGWKSSIG------------RWSRVQAEGV--------------YNSKLGVTI------- 381
Query: 386 IGSGALVGPGVIVDKNI--PPNVLVVAKQEKIV 416
+G V V+V +I P L V+ Q++I+
Sbjct: 382 LGDSVAVEDEVVVTSSIVLPNKTLNVSVQDEII 414
>gb|AAF60647.1| (AC006780) contains similarity to Pfam families PF00483
(NTP_transferase), Score=47.5, E=3e-10, N=1 and PF00132
(hexapep), Score=19.4, E=0.0011, N=1; similar to other
mannose-1-phosphate gaunyl transferases [Caenorhabditis
elegans]
Length = 401
Score = 72.6 bits (175), Expect = 8e-12
Identities = 87/353 (24%), Positives = 148/353 (41%), Gaps = 49/353 (13%)
Query: 2 KAVVLAAG--KGERLRPLTDDRPKPILKVANKPIIEYILENLDPF--VDEFIIIVKYMKE 57
KAVVL G KG R RPL+ PKP+ +A P+IE+ ++ L + E +++ + +
Sbjct: 4 KAVVLVGGPQKGTRFRPLSLQLPKPLFPIAGVPLIEHHIDQLCQLSGLSEILLLGFFPSD 63
Query: 58 KIIETLG--DEFHGKPITYVSQVEEEGTAKAIYSAKDYI---EEEEFFAIN----GDIYF 108
+ + + + I Y+ + GTA + S K I + + F IN GD+
Sbjct: 64 VFTDFISRCQQTYRVSIKYLEEPNPLGTAGGLVSFKKQILAGDPDAVFVINADVCGDLPI 123
Query: 109 EQ-----EAIRGLLHVYKKTKANAALVVKKFDDLSQLGMVKTEG-GYVREIVEKPGN-VG 161
E +++ G + T+A + G V T+ G V V+KP V
Sbjct: 124 EDMGAKLDSLSGSSMLMLTTEATRQQSIN-------FGSVVTDSEGRVIHYVDKPTTFVS 176
Query: 162 GLANLGIYIFNPDVFEFIERTQESERGEYEITDTINLMISDGRKVAYFEYSGFWSDIGRP 221
+ G+Y+ +V ++ + G + TD + + S G A + +WS
Sbjct: 177 TNISCGVYLIKAEVIRQLDLPLNGD-GIWLETDVLPQLASSGNLYA-LHTTRWWSQTKTA 234
Query: 222 WDLLEVNEYILKT-KLKHDIRGTVEEGATIIPPVEIGEGTVVRSGSYIIGPVKIGKNCRI 280
+L N + L+ K ++ R + ++G+ IIG V I + ++
Sbjct: 235 AAVLYANRHYLRLYKRRYAAR-------------------LCKNGAQIIGDVFIDPSAKV 275
Query: 281 GPNCFIRPYTSIGDNCHIGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLG 333
P I P SIG IG V IK SII+ + V S++G + +G
Sbjct: 276 HPTAKIGPNVSIGPKSVIGKGVRIKESIILPEAVIEENACVLQSVIGWRSVVG 328
>sp|P42817|GCAD_BACCL UDP-N-ACETYLGLUCOSAMINE PYROPHOSPHORYLASE
(N-ACETYLGLUCOSAMINE-1-PHOSPHATE URIDYLTRANSFERASE)
>gi|1075784|pir||S51151 N-acetylglucosamine-1-phosphate
uridyltransferase - Bacillus caldolyticus (fragment)
>gi|2126772|pir||PC4228 N-acetylglucosamine-1-phosphate
uridyltransferase (EC 2.-.-.-) - Bacillus caldolyticus
(fragment) >gi|633146|emb|CAA58681.1| (X83708)
N-acetylglucosamine-1-phosphate uridyltransferase
[Bacillus caldolyticus]
Length = 116
Score = 71.8 bits (173), Expect = 1e-11
Identities = 45/121 (37%), Positives = 63/121 (51%), Gaps = 17/121 (14%)
Query: 298 IGNAVEIKNSIIMDNSNAPHLNYVGDSIVGENTNLGAGTITANLRHDNRTIKVEIKGKLE 357
IGN VE+K S S APHL+Y+GD+ VG + NLG G+IT N N+ + K+E
Sbjct: 1 IGNFVEVKKSTFGKGSKAPHLSYIGDAEVGADVNLGCGSITVNYDGVNKHMT-----KIE 55
Query: 358 DSGRRKLGAIIGHNVKTGINVTIYPGRKIGSGALVGPGVIVDKNIPPNVLVVAKQEKIVK 417
+ GA IG NV VT +G GA V G + ++P L +A+ ++ K
Sbjct: 56 N------GAFIGCNVNLIAPVT------VGQGAYVAAGSTITNDVPGRALAIARARQVNK 103
Query: 418 E 418
E
Sbjct: 104 E 104
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.317 0.141 0.403
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 161703040
Number of Sequences: 2977
Number of extensions: 7446792
Number of successful extensions: 19175
Number of sequences better than 1.0e-10: 247
Number of HSP's better than 0.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 221
Number of HSP's that attempted gapping in prelim test: 18316
Number of HSP's gapped (non-prelim): 361
length of query: 419
length of database: 189,106,746
effective HSP length: 56
effective length of query: 363
effective length of database: 155,591,474
effective search space: 56479705062
effective search space used: 56479705062
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.6 bits)
S2: 166 (69.1 bits)