BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB1126 (eno) DE:enolase (EC 4.2.1.11) (eno)
         (430 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||H75022 phosphopyruvate hydratase (EC 4.2.1.11) PAB1126 - Py...   853  0.0
sp|O59605|ENO_PYRHO ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   812  0.0
sp|Q60173|ENO_METJA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   597  e-170
dbj|BAB07275.1| (AP001519) enolase (2-phosphoglycerate dehydrata...   520  e-146
pir||A41835 phosphopyruvate hydratase (EC 4.2.1.11) - Bacillus s...   517  e-146
sp|P37869|ENO_BACSU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   517  e-146
emb|CAC09537.1| (AL442120) enolase [Streptomyces coelicolor]          509  e-143
pir||D75251 enolase - Deinococcus radiodurans (strain R1) >gi|64...   506  e-142
sp|O66778|ENO_AQUAE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   503  e-141
sp|P42848|ENO_THEMA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   495  e-139
gb|AAD35958.1|AE001753_14 (AE001753) enolase [Thermotoga maritima]    495  e-139
sp|P96377|ENO_MYCTU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   488  e-137
emb|CAB94910.1| (AJ401152) enolase [Enterococcus faecalis]            487  e-137
dbj|BAB07786.1| (AB046715) enolase [Desulfovibrio vulgaris]           486  e-136
pir||A81841 phosphopyruvate hydratase (EC 4.2.1.11) NMA1495 [imp...   481  e-135
pir||D81100 enolase NMB1285 [imported] - Neisseria meningitidis ...   480  e-134
sp|O51312|ENO_BORBU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   474  e-133
sp|P42894|ENO_NEOFR ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   474  e-132
pir||T12341 phosphopyruvate hydratase (EC 4.2.1.11) - common ice...   473  e-132
sp|Q43130|ENO_MESCR ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   473  e-132
gb|AAC46289.1| (AF000366) enolase homolog [Borrelia burgdorferi]      473  e-132
emb|CAB75428.1| (AJ271785) enolase [Lupinus luteus]                   473  e-132
emb|CAB96173.1| (AJ271719) enolase [Spinacia oleracea]                469  e-131
sp|P77972|ENO_SYNY3 ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   468  e-131
sp|P74934|ENO_TREPA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   467  e-131
sp|O69174|ENO_STAAU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   466  e-130
sp|P07323|ENOG_RAT GAMMA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-LY...   466  e-130
gi|5803011 enolase 2, (gamma, neuronal); Enolase-2, gamma, neuro...   466  e-130
sp|P30575|ENO1_CANAL ENOLASE 1 (2-PHOSPHOGLYCERATE DEHYDRATASE) ...   466  e-130
sp|Q27727|ENO_PLAFA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   465  e-130
emb|CAA31512.1| (X13120) neurone-specific enolase [Homo sapiens]...   465  e-130
sp|P26300|ENO_LYCES ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   465  e-130
sp|P09104|ENOG_HUMAN GAMMA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-...   465  e-130
dbj|BAA76924.1| (AB026051) enolase [Plasmodium falciparum]            464  e-130
pir||JC1039 phosphopyruvate hydratase (EC 4.2.1.11) - rat             464  e-130
pir||A53665 phosphopyruvate hydratase (EC 4.2.1.11) - liver fluke     464  e-129
gi|7305027 enolase 2, gamma neuronal [Mus musculus] >gi|119348|s...   463  e-129
emb|CAC00532.1| (AJ132580) enolase, isoform 1 [Hevea brasiliensis]    463  e-129
sp|P42896|ENO_RICCO ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   462  e-129
sp|O57391|ENOG_CHICK GAMMA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-...   462  e-129
sp|O85348|ENO_NITEU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   462  e-129
sp|Q27655|ENO_FASHE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   462  e-129
pir||A72477 probable enolase APE2458 - Aeropyrum pernix (strain ...   462  e-129
sp|P25696|ENO_ARATH ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   461  e-129
sp|Q42971|ENO_ORYSA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   460  e-128
gb|AAD41646.1|AF072589_1 (AF072589) alpha enolase [Python regius]     460  e-128
sp|P42895|ENO2_MAIZE ENOLASE 2 (2-PHOSPHOGLYCERATE DEHYDRATASE 2...   460  e-128
sp|P08324|ENO_ECOLI ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   460  e-128
sp|P33675|ENO_ZYMMO ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   459  e-128
dbj|BAA81815.1| (AB029313) enolase [Streptococcus intermedius]        459  e-128
sp|Q43321|ENO_ALNGL ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   458  e-128
emb|CAC00533.1| (AJ132581) enolase, isoform 2 [Hevea brasiliensis]    458  e-128
gb|AAD41643.1|AF072586_1 (AF072586) alpha enolase [Alligator mis...   458  e-128
sp|P08734|ENO_XENLA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   457  e-128
sp|P51913|ENOA_CHICK ALPHA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-...   456  e-127
gb|AAD41645.1|AF072588_1 (AF072588) alpha enolase [Trachemys scr...   455  e-127
sp|O02654|ENO_LOLPE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   454  e-127
sp|P26301|ENO1_MAIZE ENOLASE 1 (2-PHOSPHOGLYCERATE DEHYDRATASE 1...   453  e-126
sp|P19140|ENOA_ANAPL ALPHA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-...   453  e-126
emb|CAA76735.1| (Y17298) enolase [Cunninghamella elegans]             453  e-126
sp|P42040|ENO_CLAHE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   453  e-126
gi|4503571 enolase 1, (alpha); Enolase-1, alpha; phosphopyruvate...   453  e-126
gb|AAF13454.1|AF205070_1 (AF205070) enolase [Mastigamoeba balamu...   453  e-126
emb|CAA57795.1| (X82400) enolase [Escherichia coli]                   453  e-126
sp|P17182|ENOA_MOUSE ALPHA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-...   451  e-126
pir||S06756 phosphopyruvate hydratase (EC 4.2.1.11) beta - human...   451  e-126
gi|4503573 enolase 3, (beta, muscle); Enolase-3, beta, muscle [H...   451  e-126
sp|P33676|ENO_SCHJA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   451  e-126
emb|CAA59331.1| (X84907) carbonate dehydratase [Homo sapiens]         451  e-126
gi|11426964 enolase 3, (beta, muscle) [Homo sapiens] >gi|416950|...   450  e-125
sp|Q27527|ENO_CAEEL ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   450  e-125
gb|AAD41644.1|AF072587_1 (AF072587) alpha enolase [Sceloporus un...   450  e-125
pir||A37210 phosphopyruvate hydratase (EC 4.2.1.11) beta - rabbit     450  e-125
sp|P25704|ENOB_RABIT BETA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-L...   450  e-125
gi|6679651 enolase 3, beta muscle [Mus musculus] >gi|119344|sp|P...   449  e-125
emb|CAB96125.1| (AJ272111) enolase [Euglena gracilis]                 449  e-125
gi|6978809 enolase 1, alpha [Rattus norvegicus] >gi|119341|sp|P0...   449  e-125
gb|AAF71925.1|AF260259_1 (AF260259) beta beta enolase [Oryctolag...   448  e-125
pir||S43113 phosphopyruvate hydratase (EC 4.2.1.11) - fungus  (C...   446  e-124
gb|AAF36733.1| (AC016662) putative enolase; 31277-33713 [Arabido...   446  e-124
sp|Q12560|ENO_ASPOR ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   445  e-124
pir||T39737 enolase - fission yeast (Schizosaccharomyces pombe) ...   444  e-124
sp|Q27877|ENO_SCHMA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   443  e-123
gb|AAC78141.1| (AF100985) phosphopyruvate hydratase [Penaeus mon...   442  e-123
sp|Q9ZMS6|ENO_HELPJ ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   441  e-123
gb|AAD33073.1|AF149256_1 (AF149256) alpha enolase [Bos taurus]        441  e-123
gb|AAF73201.1|AF152348_1 (AF152348) enolase [Trypanosoma brucei ...   441  e-123
pir||E82076 enolase VC2447 [imported] - Vibrio cholerae (group O...   441  e-123
sp|P43806|ENO_HAEIN ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   441  e-123
sp|P42448|ENO_CAMJE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   441  e-123
pir||F82700 enolase XF1291 [imported] - Xylella fastidiosa (stra...   439  e-122
pdb|1PDZ|   Mol_id: 1; Molecule: Enolase; Chain: Null; Synonym: ...   439  e-122
sp|P56252|ENO_HOMGA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   439  e-122
sp|P48285|ENO_HELPY ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   439  e-122
emb|CAB94039.1| (AL358652) enolase [Leishmania major]                 437  e-121
emb|CAB96126.1| (AJ272112) chloroplast enolase [Euglena gracilis]     436  e-121
pir||H83191 enolase PA3635 [imported] - Pseudomonas aeruginosa (...   436  e-121
gi|6978811 muscle specific enolase (beta beta enolose) (two spli...   436  e-121
gi|6321693 enolase I; Eno1p [Saccharomyces cerevisiae] >gi|21445...   436  e-121
sp|P00924|ENO1_YEAST ENOLASE 1 (2-PHOSPHOGLYCERATE DEHYDRATASE) ...   436  e-121
pdb|1ONE|A Chain A, Yeast Enolase Complexed With An Equilibrium ...   436  e-121
pdb|4ENL|   Enolase (E.C.4.2.1.11) (2-Phospho-D-Glycerate Hydrol...   434  e-121
gb|AAD02812.1| (AF063247) enolase [Pneumocystis carinii f. sp. r...   433  e-120
sp|P07322|ENOB_CHICK BETA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-L...   433  e-120
sp|O52191|ENO_STRTR ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   432  e-120
gb|AAF51344.1| (AE003585) Eno gene product [Drosophila melanogas...   432  e-120
pir||I56569 gamma enolase - human (fragment) >gi|182118|gb|AAA52...   431  e-120
sp|P15007|ENO_DROME ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   431  e-120
sp|P51555|ENO1_ENTHI ENOLASE 1 (2-PHOSPHOGLYCERATE DEHYDRATASE) ...   430  e-119
gb|AAD51128.1|AF051910_1 (AF051910) enolase [Toxoplasma gondii]       430  e-119
gi|6321968 enolase; Eno2p [Saccharomyces cerevisiae] >gi|119337|...   428  e-119
emb|CAC16971.1| (AL450350) enolase [Streptomyces coelicolor]          428  e-119
sp|P40370|ENO1_SCHPO ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2...   427  e-118
pir||A23850 phosphopyruvate hydratase (EC 4.2.1.11), skeletal mu...   426  e-118
sp|P75189|ENO_MYCPN ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   421  e-117
pir||E81654 enolase TC0876 [imported] - Chlamydia muridarum (str...   419  e-116
sp|Q9Z7A6|ENO_CHLPN ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   417  e-115
gi|6323985 Ymr323wp [Saccharomyces cerevisiae] >gi|1706698|sp|P4...   416  e-115
pir||G81504 enolase CP1071 [imported] - Chlamydophila pneumoniae...   416  e-115
sp|O84591|ENO_CHLTR ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   414  e-114
gi|6324969 enolase homolog; Err1p [Saccharomyces cerevisiae] >gi...   413  e-114
sp|P57492|ENO_BUCAI ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   411  e-114
dbj|BAA88483.1| (AB025330) enolase-2 [Lampetra reissneri]             408  e-113
gb|AAB87891.1| (AF025806) enolase [Drosophila subobscura]             406  e-112
sp|P47647|ENO_MYCGE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   403  e-111
gb|AAB87890.1| (AF025805) enolase [Drosophila pseudoobscura]          403  e-111
dbj|BAA88479.1| (AB025326) enolase [Eptatretus burgeri]               403  e-111
gb|AAC95183.1| (AC004561) putative enolase (2-phospho-D-glycerat...   400  e-110
dbj|BAA88482.1| (AB025329) enolase-1 [Lampetra reissneri]             400  e-110
sp|P31683|ENO_CHLRE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   393  e-108
gb|AAA49217.1| (M55143) alpha-enolase/tau-crystallin [Anas platy...   388  e-107
gb|AAA37554.1| (M20745) muscle-specific enolase beta subunit (EC...   374  e-103
pir||H82922 enolase UU184 [imported] - Ureaplasma urealyticum >g...   369  e-101
gi|7657062 enolase alpha, lung-specific [Homo sapiens] >gi|72942...   363  2e-99
gb|AAK41195.1| Enolase [Sulfolobus solfataricus]                      356  3e-97
gb|AAB88178.1| (AF035286) alpha enolase [Homo sapiens]                349  4e-95
sp|O26149|ENO_METTH ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-...   329  3e-89
gb|AAC48992.1| (U23472) enolase homolog;  Method: conceptual tra...   289  3e-77
gb|AAC39935.1| (U88968) alpha enolase like 1 [Homo sapiens]           280  1e-74
emb|CAC12011.1| (AL445065) enolase related protein [Thermoplasma...   272  4e-72
emb|CAB94588.1| (AL359213) ENO3, muscle enolase 3 beta [Homo sap...   170  3e-41
gi|10835228 MYC promoter-binding protein 1 [Homo sapiens] >gi|12...   155  6e-37
gb|AAA24486.1| (M12843) enolase [Escherichia coli]                    136  6e-31

>pir||H75022 phosphopyruvate hydratase (EC 4.2.1.11) PAB1126 - Pyrococcus abyssi
           (strain Orsay) >gi|5459136|emb|CAB50622.1| (AJ248288)
           enolase (EC 4.2.1.11) (eno) [Pyrococcus abyssi]
           Length = 430
           
 Score =  853 bits (2180), Expect = 0.0
 Identities = 430/430 (100%), Positives = 430/430 (100%)

Query: 1   MTMENPYEIVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK 60
           MTMENPYEIVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK
Sbjct: 1   MTMENPYEIVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK 60

Query: 61  RYHGKGVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLA 120
           RYHGKGVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLA
Sbjct: 61  RYHGKGVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLA 120

Query: 121 VAKAAANALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFRE 180
           VAKAAANALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFRE
Sbjct: 121 VAKAAANALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFRE 180

Query: 181 AIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGE 240
           AIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGE
Sbjct: 181 AIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGE 240

Query: 241 EIALALDAASSEFYKDGKYIVSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFV 300
           EIALALDAASSEFYKDGKYIVSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFV
Sbjct: 241 EIALALDAASSEFYKDGKYIVSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFV 300

Query: 301 MITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRA 360
           MITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRA
Sbjct: 301 MITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRA 360

Query: 361 GYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVY 420
           GYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVY
Sbjct: 361 GYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVY 420

Query: 421 AGKNFRKVFF 430
           AGKNFRKVFF
Sbjct: 421 AGKNFRKVFF 430


>sp|O59605|ENO_PYRHO ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|7436873|pir||F71209 probable
           phosphoglycerate dehydratase - Pyrococcus horikoshii
           >gi|3258386|dbj|BAA31069.1| (AP000007) 428aa long
           hypothetical phosphoglycerate dehydratase [Pyrococcus
           horikoshii]
           Length = 428
           
 Score =  812 bits (2075), Expect = 0.0
 Identities = 400/428 (93%), Positives = 418/428 (97%)

Query: 3   MENPYEIVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGKRY 62
           MENPYEI A++AREILDSRGNPTVEVDVHTPI+MGRAAVPSGASTGTHEAVELRDGGKRY
Sbjct: 1   MENPYEITAIVAREILDSRGNPTVEVDVHTPIAMGRAAVPSGASTGTHEAVELRDGGKRY 60

Query: 63  HGKGVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVA 122
           HGKGVRRAVENVNKIIAPEL+GMDVRWQREID+LLIELDGTENKSNLGANAILAVSLAVA
Sbjct: 61  HGKGVRRAVENVNKIIAPELIGMDVRWQREIDKLLIELDGTENKSNLGANAILAVSLAVA 120

Query: 123 KAAANALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182
           KAAAN+LELPLYQYLGGVNAYVLPVPLSNVINGGVHAGN+LDFQEFMIMPIGA+SFREAI
Sbjct: 121 KAAANSLELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNELDFQEFMIMPIGASSFREAI 180

Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242
           RWVSETYHVLK+VI  KYGKNAVNVGDEGGFAPPMKEVTEPLD LIKAIEEAGYKPG+EI
Sbjct: 181 RWVSETYHVLKRVIMGKYGKNAVNVGDEGGFAPPMKEVTEPLDALIKAIEEAGYKPGDEI 240

Query: 243 ALALDAASSEFYKDGKYIVSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMI 302
           ALA+DAASSEF+KDGKYIV GKEYTREELL+LYKEL STYPIVSIEDPFHEEDWEGFVMI
Sbjct: 241 ALAIDAASSEFFKDGKYIVGGKEYTREELLDLYKELVSTYPIVSIEDPFHEEDWEGFVMI 300

Query: 303 TRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGY 362
           T ELGKK+QIVGDDLFVTNP+RLKKGIE+GAANALLLKVNQIGTLTEAMDAAY AFRAGY
Sbjct: 301 TNELGKKIQIVGDDLFVTNPRRLKKGIELGAANALLLKVNQIGTLTEAMDAAYTAFRAGY 360

Query: 363 GVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAG 422
            V+VSHRSGETED TIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEG+AVYAG
Sbjct: 361 SVIVSHRSGETEDTTIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGIAVYAG 420

Query: 423 KNFRKVFF 430
           KNFRKVFF
Sbjct: 421 KNFRKVFF 428


>sp|Q60173|ENO_METJA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|2118303|pir||A64329 phosphopyruvate
           hydratase (EC 4.2.1.11) - Methanococcus jannaschii
           >gi|1590967|gb|AAB98220.1| (U67479) enolase (eno)
           [Methanococcus jannaschii]
           Length = 427
           
 Score =  597 bits (1522), Expect = e-170
 Identities = 306/428 (71%), Positives = 356/428 (82%), Gaps = 6/428 (1%)

Query: 3   MENPYEIVAVIAREILDSRGNPTVEVDVHTPIS-MGRAAVPSGASTGTHEAVELRDGGKR 61
           M+  +EI  ++ARE++DSRGNPTVEV+V T  +  G A VPSGASTGTHEA+ELRD  KR
Sbjct: 5   MDERFEIKDIVAREVIDSRGNPTVEVEVITKGNGYGSAIVPSGASTGTHEALELRDKEKR 64

Query: 62  YHGKGVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAV 121
           + GKGV  AVENVN II PE++G D R QREID ++IELDGT NKS LGANAILAVSLAV
Sbjct: 65  FGGKGVLMAVENVNSIIRPEILGYDARMQREIDTIMIELDGTPNKSRLGANAILAVSLAV 124

Query: 122 AKAAANALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREA 181
           AKAAA   ++PLY+YLGG N+YV+PVP+ NVINGG HAGNDLD QEFMIMP+GA S  EA
Sbjct: 125 AKAAAATAKIPLYKYLGGFNSYVMPVPMMNVINGGKHAGNDLDLQEFMIMPVGATSISEA 184

Query: 182 IRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEE 241
           +R  SE YHVLK VI EKYGKNAVNVGDEGGFAPP+K   E LD+L +++++AGY+  +E
Sbjct: 185 VRMGSEVYHVLKNVILEKYGKNAVNVGDEGGFAPPLKTSREALDLLTESVKKAGYE--DE 242

Query: 242 IALALDAASSEFYKDGKYIVSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVM 301
           +  ALDAA+SEFYKDG Y V GK+ TREELL+ YK L   YPIVSIEDPFHEED+EGF M
Sbjct: 243 VVFALDAAASEFYKDGYYYVEGKKLTREELLDYYKALVDEYPIVSIEDPFHEEDFEGFAM 302

Query: 302 ITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAG 361
           IT+EL   +QIVGDDLFVTN +RL+KGIEM AANALLLKVNQIGTL+EA+DAA +AFR G
Sbjct: 303 ITKEL--DIQIVGDDLFVTNVERLRKGIEMKAANALLLKVNQIGTLSEAVDAAQLAFRNG 360

Query: 362 YGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYA 421
           YGVVVSHRSGETED TIADL+VALN+GQIKTGAPAR +R AKYNQLIRIE+EL G++ YA
Sbjct: 361 YGVVVSHRSGETEDTTIADLSVALNSGQIKTGAPARGERTAKYNQLIRIEQEL-GLSKYA 419

Query: 422 GKNFRKVF 429
           G+NFR  F
Sbjct: 420 GRNFRCPF 427


>dbj|BAB07275.1| (AP001519) enolase (2-phosphoglycerate dehydratase) [Bacillus
           halodurans]
           Length = 429
           
 Score =  520 bits (1325), Expect = e-146
 Identities = 271/419 (64%), Positives = 327/419 (77%), Gaps = 7/419 (1%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRDGGKRYHGKGV 67
           I  V ARE+LDSRGNPTVEV+V+    +MGRA VPSGASTG +EAVELRDGG+R+ GKGV
Sbjct: 4   ITDVYAREVLDSRGNPTVEVEVYLESGAMGRALVPSGASTGEYEAVELRDGGERFLGKGV 63

Query: 68  RRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAAN 127
            +AVENVN++IAPEL+G D   Q  ID+ +IELDGTENK  LGANAIL VS+AVA+AAAN
Sbjct: 64  LKAVENVNEVIAPELIGFDALDQIGIDQHMIELDGTENKGKLGANAILGVSMAVARAAAN 123

Query: 128 ALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVSE 187
           AL+LPLY YLGG NA  LPVP+ N+INGG HA N++D QEFMIMP+GA SF+EA+R  +E
Sbjct: 124 ALDLPLYVYLGGFNAKQLPVPMMNIINGGEHADNNVDIQEFMIMPVGAESFKEALRTGTE 183

Query: 188 TYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALALD 247
            +H LKKV+  K G N   VGDEGGFAP +    E L  +I+AIE+AGY PGE++ LA+D
Sbjct: 184 IFHSLKKVLKSK-GYNTA-VGDEGGFAPNLSSNEEALQTIIEAIEQAGYTPGEQVKLAMD 241

Query: 248 AASSEFY--KDGKYIVS--GKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMIT 303
            ASSE Y  +DGKY +S  GK  + EE++  Y+EL + YPI+SIED   E DWEG  M+T
Sbjct: 242 VASSELYNKEDGKYHLSGEGKVLSSEEMVAFYEELVAKYPIISIEDGLDENDWEGHKMLT 301

Query: 304 RELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYG 363
             LG KVQ+VGDDLFVTN K+L +GIE G  N++L+KVNQIGTLTE  DA  MA RAGY 
Sbjct: 302 DRLGDKVQLVGDDLFVTNTKKLAQGIEQGVGNSILIKVNQIGTLTETFDAIEMAKRAGYT 361

Query: 364 VVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAG 422
            V+SHRSGETED+TIAD+AVA NAGQIKTGAP+R+DR AKYNQL+RIE+EL  +A Y G
Sbjct: 362 AVISHRSGETEDSTIADIAVATNAGQIKTGAPSRTDRVAKYNQLLRIEDELGNLAQYNG 420


>pir||A41835 phosphopyruvate hydratase (EC 4.2.1.11) - Bacillus subtilis
           >gi|460259|gb|AAA21681.1| (L29475) enolase [Bacillus
           subtilis]
           Length = 430
           
 Score =  517 bits (1318), Expect = e-146
 Identities = 272/425 (64%), Positives = 332/425 (78%), Gaps = 9/425 (2%)

Query: 6   PYEIVAVIAREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRDGGK-RYH 63
           PY IV V ARE+LDSRGNPTVEV+V+T   + GRA VPSGASTG +EAVELRDG K RY 
Sbjct: 2   PY-IVDVYAREVLDSRGNPTVEVEVYTETGAFGRALVPSGASTGQYEAVELRDGDKDRYL 60

Query: 64  GKGVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAK 123
           GKGV  AV NVN+IIAPEL+G DV  Q  ID+LLIELDGTENK  LGANAIL VS+A A+
Sbjct: 61  GKGVLTAVNNVNEIIAPELLGFDVTEQNAIDQLLIELDGTENKGKLGANAILGVSMACAR 120

Query: 124 AAANALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIR 183
           AAA+ L++PLYQYLGG N+  LPVP+ N++NGG HA N++D QEFMIMP+GA +FREA+R
Sbjct: 121 AAADFLQIPLYQYLGGFNSKTLPVPMMNIVNGGEHADNNVDIQEFMIMPVGAPNFREALR 180

Query: 184 WVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIA 243
             ++ +H LK V++ K G N   VGDEGGFAP +    E L  +++AIE+AG+KPGEE+ 
Sbjct: 181 MGAQIFHSLKSVLSAK-GLNTA-VGDEGGFAPNLGSNEEALQTIVEAIEKAGFKPGEEVK 238

Query: 244 LALDAASSEFY--KDGKYIVSGKEY--TREELLELYKELTSTYPIVSIEDPFHEEDWEGF 299
           LA+DAASSEFY  +DGKY +SG+    T  E+++ Y+EL S YPI+SIED   E DWEG 
Sbjct: 239 LAMDAASSEFYNKEDGKYHLSGEGVVKTSAEMVDWYEELVSKYPIISIEDGLDENDWEGH 298

Query: 300 VMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFR 359
            ++T  LGKKVQ+VGDDLFVTN K+L +GI+ G  N++L+KVNQIGTLTE  DA  MA R
Sbjct: 299 KLLTERLGKKVQLVGDDLFVTNTKKLSEGIKNGVGNSILIKVNQIGTLTETFDAIEMAKR 358

Query: 360 AGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAV 419
           AGY  V+SHRSGETED+TIAD+AVA NAGQIKTGAP+R+DR AKYNQL+RIE++L   A 
Sbjct: 359 AGYTAVISHRSGETEDSTIADIAVATNAGQIKTGAPSRTDRVAKYNQLLRIEDQLAETAQ 418

Query: 420 YAGKN 424
           Y G N
Sbjct: 419 YHGIN 423


>sp|P37869|ENO_BACSU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|7436878|pir||B69620 phosphopyruvate
           hydratase (EC 4.2.1.11) [validated] - Bacillus subtilis
           >gi|2635903|emb|CAB15395.1| (Z99121) enolase [Bacillus
           subtilis]
           Length = 430
           
 Score =  517 bits (1318), Expect = e-146
 Identities = 272/425 (64%), Positives = 332/425 (78%), Gaps = 9/425 (2%)

Query: 6   PYEIVAVIAREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRDGGK-RYH 63
           PY IV V ARE+LDSRGNPTVEV+V+T   + GRA VPSGASTG +EAVELRDG K RY 
Sbjct: 2   PY-IVDVYAREVLDSRGNPTVEVEVYTETGAFGRALVPSGASTGEYEAVELRDGDKDRYL 60

Query: 64  GKGVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAK 123
           GKGV  AV NVN+IIAPEL+G DV  Q  ID+LLIELDGTENK  LGANAIL VS+A A+
Sbjct: 61  GKGVLTAVNNVNEIIAPELLGFDVTEQNAIDQLLIELDGTENKGKLGANAILGVSMACAR 120

Query: 124 AAANALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIR 183
           AAA+ L++PLYQYLGG N+  LPVP+ N++NGG HA N++D QEFMIMP+GA +FREA+R
Sbjct: 121 AAADFLQIPLYQYLGGFNSKTLPVPMMNIVNGGEHADNNVDIQEFMIMPVGAPNFREALR 180

Query: 184 WVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIA 243
             ++ +H LK V++ K G N   VGDEGGFAP +    E L  +++AIE+AG+KPGEE+ 
Sbjct: 181 MGAQIFHSLKSVLSAK-GLNTA-VGDEGGFAPNLGSNEEALQTIVEAIEKAGFKPGEEVK 238

Query: 244 LALDAASSEFY--KDGKYIVSGKEY--TREELLELYKELTSTYPIVSIEDPFHEEDWEGF 299
           LA+DAASSEFY  +DGKY +SG+    T  E+++ Y+EL S YPI+SIED   E DWEG 
Sbjct: 239 LAMDAASSEFYNKEDGKYHLSGEGVVKTSAEMVDWYEELVSKYPIISIEDGLDENDWEGH 298

Query: 300 VMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFR 359
            ++T  LGKKVQ+VGDDLFVTN K+L +GI+ G  N++L+KVNQIGTLTE  DA  MA R
Sbjct: 299 KLLTERLGKKVQLVGDDLFVTNTKKLSEGIKNGVGNSILIKVNQIGTLTETFDAIEMAKR 358

Query: 360 AGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAV 419
           AGY  V+SHRSGETED+TIAD+AVA NAGQIKTGAP+R+DR AKYNQL+RIE++L   A 
Sbjct: 359 AGYTAVISHRSGETEDSTIADIAVATNAGQIKTGAPSRTDRVAKYNQLLRIEDQLAETAQ 418

Query: 420 YAGKN 424
           Y G N
Sbjct: 419 YHGIN 423


>emb|CAC09537.1| (AL442120) enolase [Streptomyces coelicolor]
           Length = 426
           
 Score =  509 bits (1297), Expect = e-143
 Identities = 264/418 (63%), Positives = 321/418 (76%), Gaps = 4/418 (0%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRDGG-KRYHGKG 66
           I  V+AREILDSRGNPTVEV+V     S GRAAVPSGASTG  EA+ELRDG   RY GKG
Sbjct: 4   IDVVVAREILDSRGNPTVEVEVGLDDGSTGRAAVPSGASTGAFEAIELRDGDPSRYLGKG 63

Query: 67  VRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAA 126
           V +AV  V + I PELVG D   QR ID+ + +LD T+NK +LGANAIL VSLAVA AA+
Sbjct: 64  VEKAVLAVIEQIGPELVGYDATEQRLIDQAMFDLDATDNKGSLGANAILGVSLAVAHAAS 123

Query: 127 NALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVS 186
            A +LPL++YLGG NA++LPVP+ N++NGG HA +++D QEFMI PIGA SF EA+RW +
Sbjct: 124 EASDLPLFRYLGGPNAHLLPVPMMNILNGGSHADSNVDIQEFMIAPIGAESFSEALRWGA 183

Query: 187 ETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALAL 246
           E YH LKKV+  K    A  +GDEGGFAP +    E LD++++AI+EAGY PGE+IALAL
Sbjct: 184 EVYHTLKKVLKNK--GLATGLGDEGGFAPNLGSNREALDLILEAIKEAGYTPGEQIALAL 241

Query: 247 DAASSEFYKDGKYIVSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMITREL 306
           D A+SEFYKDG Y   GK  +  E+ E Y EL   YP+VSIEDP  E+DW+G+  IT +L
Sbjct: 242 DVAASEFYKDGSYAFEGKNRSAAEMTEYYAELVEAYPLVSIEDPLFEDDWDGWNTITAKL 301

Query: 307 GKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYGVVV 366
           G KVQ+VGDDLFVTNP+RL +GIE  +ANALL+KVNQIG+LTE +DA  +A R G+  ++
Sbjct: 302 GDKVQLVGDDLFVTNPERLARGIEENSANALLVKVNQIGSLTETLDAVELAQRNGFKCMM 361

Query: 367 SHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAGKN 424
           SHRSGETED TIADLAVA N GQIKTGAPARS+R AKYNQL+RIEE L+  AVYAG++
Sbjct: 362 SHRSGETEDVTIADLAVATNCGQIKTGAPARSERVAKYNQLLRIEEILDDAAVYAGRS 419


>pir||D75251 enolase - Deinococcus radiodurans (strain R1)
           >gi|6460466|gb|AAF12173.1|AE002092_11 (AE002092) enolase
           [Deinococcus radiodurans]
           Length = 422
           
 Score =  506 bits (1289), Expect = e-142
 Identities = 253/418 (60%), Positives = 329/418 (78%), Gaps = 5/418 (1%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISM-GRAAVPSGASTGTHEAVELRDGGKRYHGKGV 67
           I  VIARE+LDSRGNPTVE +VH      GRA VPSGASTG+HEA+ELRDGG+RY GKGV
Sbjct: 3   IEKVIAREVLDSRGNPTVEAEVHLDSGFSGRAIVPSGASTGSHEALELRDGGERYMGKGV 62

Query: 68  RRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAAN 127
            RAV+NV + + P L+GMD   Q  ID+ L+++DGT NK N+G NAILAVSLA A+AAA 
Sbjct: 63  ERAVQNVREALGPALIGMDASEQAAIDKALMDVDGTSNKGNMGGNAILAVSLATARAAAA 122

Query: 128 ALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVSE 187
            L++PLY+YLGG NA  LPVP+ NVINGG HA N +DFQEFM+MP+GA SFREA+R+ +E
Sbjct: 123 ELDIPLYRYLGGSNAKTLPVPMMNVINGGAHADNSVDFQEFMVMPVGAPSFREALRYGAE 182

Query: 188 TYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALALD 247
           T+H LKKV++ + G N  NVGDEGGFAP +K   E L+VL++AI++AGY+PG++I +ALD
Sbjct: 183 TFHHLKKVLSGR-GYN-TNVGDEGGFAPDLKSNEEALEVLLEAIQQAGYEPGKDICIALD 240

Query: 248 AASSEFYKDGKYIV--SGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMITRE 305
            A +E YKDG+Y +   G+  + +E+++ + + TS YPIVSIED   E+DW+G+  +T +
Sbjct: 241 PAVTELYKDGQYHLESEGRVLSSDEMIDFWADWTSRYPIVSIEDGLAEDDWDGWERLTAK 300

Query: 306 LGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYGVV 365
           +G K Q+VGDDLFVTNP+RL++GI+    NA+L+KVNQIG+LTE+MDA  +A R  YG +
Sbjct: 301 VGAKTQLVGDDLFVTNPERLQQGIDRKVGNAILVKVNQIGSLTESMDAIELAKRHHYGTI 360

Query: 366 VSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAGK 423
           +SHRSGE+EDA IADLAVA NAGQIKTG+ +RSDR AKYNQL+RIE++L   AV+ G+
Sbjct: 361 ISHRSGESEDAFIADLAVATNAGQIKTGSASRSDRIAKYNQLLRIEDQLGDRAVFPGR 418


>sp|O66778|ENO_AQUAE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|7436875|pir||F70343 enolase - Aquifex
           aeolicus >gi|2983135|gb|AAC06738.1| (AE000692) enolase
           [Aquifex aeolicus]
           Length = 426
           
 Score =  503 bits (1280), Expect = e-141
 Identities = 259/417 (62%), Positives = 319/417 (76%), Gaps = 4/417 (0%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRDGG-KRYHGKG 66
           I  V  RE+LDSRGNPTVEV+V     ++GRA VPSGASTG  EA+ELRDG  KRY GKG
Sbjct: 4   IKRVHGREVLDSRGNPTVEVEVELESGALGRAIVPSGASTGEREALELRDGDPKRYLGKG 63

Query: 67  VRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAA 126
           V +AV+NVN +IA  LVG++   QREID++LIELDGTENKS LGANAIL  S+AVA+AAA
Sbjct: 64  VLKAVDNVNGVIAKALVGLEPYNQREIDQILIELDGTENKSKLGANAILGTSMAVARAAA 123

Query: 127 NALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVS 186
           N L +PLY+YLGG   Y LPVPL NVINGG HA N+LD QEFMI+P+   +FREA+R   
Sbjct: 124 NELGIPLYEYLGGKFGYRLPVPLMNVINGGAHADNNLDIQEFMIVPVCGGAFREALRAGV 183

Query: 187 ETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALAL 246
           ET+H LKK++ EK    + NVGDEGGFAP +    E LD+L++AIE+AGYKPGE+I LAL
Sbjct: 184 ETFHHLKKILKEK--GYSTNVGDEGGFAPNLNSSEEALDILMQAIEKAGYKPGEDILLAL 241

Query: 247 DAASSEFYKDGKYIVSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMITREL 306
           D ASSEFY++G Y   GKE + EE++E Y++L   YPI+SIEDP  E DWEG+  IT+ L
Sbjct: 242 DVASSEFYENGVYKFEGKERSAEEMIEFYEKLIQKYPIISIEDPMSENDWEGWKEITKRL 301

Query: 307 GKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYGVVV 366
           G KVQ+VGDDLF TNPK L+KGIE G ANA+L+K+NQIGT++E +D   +A    Y  ++
Sbjct: 302 GDKVQLVGDDLFTTNPKILRKGIEEGVANAILVKLNQIGTVSETLDTVMLAKERNYSAII 361

Query: 367 SHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAGK 423
           SHRSGETED  I+ LAVA NAGQIKTG+ +R+DR AKYN+L+RIEE L   AV+ G+
Sbjct: 362 SHRSGETEDTFISHLAVATNAGQIKTGSASRTDRIAKYNELLRIEERLGNGAVFWGR 418


>sp|P42848|ENO_THEMA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|7436890|pir||G72323 phosphopyruvate
           hydratase (EC 4.2.1.11) - Thermotoga maritima (strain
           MSB8)
           Length = 429
           
 Score =  495 bits (1261), Expect = e-139
 Identities = 266/426 (62%), Positives = 325/426 (75%), Gaps = 7/426 (1%)

Query: 8   EIVAVIAREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRDGGK-RYHGK 65
           EIV V ARE+LDSRGNPTVE +V     +MGRA VPSGASTG  EA+E+RD  K RY GK
Sbjct: 4   EIVDVRAREVLDSRGNPTVEAEVVLEDGTMGRAIVPSGASTGKFEALEIRDKDKKRYLGK 63

Query: 66  GVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
           GV +AVENVN+ IAP L+GM+   Q  +D+ LIELDGTENKS LGANAILAVS+AVA+AA
Sbjct: 64  GVLKAVENVNETIAPALIGMNAFDQPLVDKTLIELDGTENKSKLGANAILAVSMAVARAA 123

Query: 126 ANALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWV 185
           AN L LPLY+YLGGVNA VLPVPL NVINGG HA N+LD QEFMI+P G +SFREA+R  
Sbjct: 124 ANYLGLPLYKYLGGVNAKVLPVPLMNVINGGQHADNNLDLQEFMIVPAGFDSFREALRAG 183

Query: 186 SETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALA 245
           +E +H LKK++ E    +   VGDEGGFAP +    E + VLI+AIE+AGYKPGEE+ +A
Sbjct: 184 AEIFHTLKKILHE--AGHVTAVGDEGGFAPNLSSNEEAIKVLIEAIEKAGYKPGEEVFIA 241

Query: 246 LDAASSEFYKD--GKYIVSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMIT 303
           LD A+S FY +  G Y V G+E + E L+  Y+EL + YPI+SIEDPF EEDW+ FV  T
Sbjct: 242 LDCAASSFYDEEKGVYYVDGEEKSSEVLMGYYEELVAKYPIISIEDPFAEEDWDAFVEFT 301

Query: 304 RELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYG 363
           + +G KVQIVGDDL+VTN KRL KGIE+ A N++L+K+NQIGT+TE +DA  MA +    
Sbjct: 302 KRVGNKVQIVGDDLYVTNVKRLSKGIELKATNSILIKLNQIGTVTETLDAVEMAQKNNMT 361

Query: 364 VVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAG- 422
            ++SHRSGE+ED  IADLAVA NAG IKTG+ +RS+R AKYNQL+RIEEEL  VA + G 
Sbjct: 362 AIISHRSGESEDTFIADLAVATNAGFIKTGSLSRSERIAKYNQLLRIEEELGKVAEFRGL 421

Query: 423 KNFRKV 428
           K+F  +
Sbjct: 422 KSFYSI 427


>gb|AAD35958.1|AE001753_14 (AE001753) enolase [Thermotoga maritima]
           Length = 427
           
 Score =  495 bits (1261), Expect = e-139
 Identities = 266/426 (62%), Positives = 325/426 (75%), Gaps = 7/426 (1%)

Query: 8   EIVAVIAREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRDGGK-RYHGK 65
           EIV V ARE+LDSRGNPTVE +V     +MGRA VPSGASTG  EA+E+RD  K RY GK
Sbjct: 2   EIVDVRAREVLDSRGNPTVEAEVVLEDGTMGRAIVPSGASTGKFEALEIRDKDKKRYLGK 61

Query: 66  GVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
           GV +AVENVN+ IAP L+GM+   Q  +D+ LIELDGTENKS LGANAILAVS+AVA+AA
Sbjct: 62  GVLKAVENVNETIAPALIGMNAFDQPLVDKTLIELDGTENKSKLGANAILAVSMAVARAA 121

Query: 126 ANALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWV 185
           AN L LPLY+YLGGVNA VLPVPL NVINGG HA N+LD QEFMI+P G +SFREA+R  
Sbjct: 122 ANYLGLPLYKYLGGVNAKVLPVPLMNVINGGQHADNNLDLQEFMIVPAGFDSFREALRAG 181

Query: 186 SETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALA 245
           +E +H LKK++ E    +   VGDEGGFAP +    E + VLI+AIE+AGYKPGEE+ +A
Sbjct: 182 AEIFHTLKKILHE--AGHVTAVGDEGGFAPNLSSNEEAIKVLIEAIEKAGYKPGEEVFIA 239

Query: 246 LDAASSEFYKD--GKYIVSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMIT 303
           LD A+S FY +  G Y V G+E + E L+  Y+EL + YPI+SIEDPF EEDW+ FV  T
Sbjct: 240 LDCAASSFYDEEKGVYYVDGEEKSSEVLMGYYEELVAKYPIISIEDPFAEEDWDAFVEFT 299

Query: 304 RELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYG 363
           + +G KVQIVGDDL+VTN KRL KGIE+ A N++L+K+NQIGT+TE +DA  MA +    
Sbjct: 300 KRVGNKVQIVGDDLYVTNVKRLSKGIELKATNSILIKLNQIGTVTETLDAVEMAQKNNMT 359

Query: 364 VVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAG- 422
            ++SHRSGE+ED  IADLAVA NAG IKTG+ +RS+R AKYNQL+RIEEEL  VA + G 
Sbjct: 360 AIISHRSGESEDTFIADLAVATNAGFIKTGSLSRSERIAKYNQLLRIEEELGKVAEFRGL 419

Query: 423 KNFRKV 428
           K+F  +
Sbjct: 420 KSFYSI 425


>sp|P96377|ENO_MYCTU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|7436874|pir||B70623 probable enolase -
           Mycobacterium tuberculosis (strain H37RV)
           >gi|1870005|emb|CAB06856.1| (Z92539) eno [Mycobacterium
           tuberculosis]
           Length = 429
           
 Score =  488 bits (1244), Expect = e-137
 Identities = 249/416 (59%), Positives = 315/416 (74%), Gaps = 4/416 (0%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHT-PISMGRAAVPSGASTGTHEAVELRDGGKRYHGKGV 67
           I  V AREILDSRGNPTVEV+V     +  RAAVPSGASTG HEAVELRDGG RY GKGV
Sbjct: 4   IEQVRAREILDSRGNPTVEVEVALIDGTFARAAVPSGASTGEHEAVELRDGGDRYGGKGV 63

Query: 68  RRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAAN 127
           ++AV+ V   I P ++G++   QR +D+ L++LDGT +KS LG NAIL VSLAVAKAAA+
Sbjct: 64  QKAVQAVLDEIGPAVIGLNADDQRLVDQALVDLDGTPDKSRLGGNAILGVSLAVAKAAAD 123

Query: 128 ALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVSE 187
           + ELPL++Y+GG NA++LPVP+ N++NGG HA   +D QEFM+ PIGA SF EA+RW +E
Sbjct: 124 SAELPLFRYVGGPNAHILPVPMMNILNGGAHADTAVDIQEFMVAPIGAPSFVEALRWGAE 183

Query: 188 TYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALALD 247
            YH LK V+ +K G +   +GDEGGFAP +   T  LD++ +AIE AG +PG ++ALALD
Sbjct: 184 VYHALKSVL-KKEGLST-GLGDEGGFAPDVAGTTAALDLISRAIESAGLRPGADVALALD 241

Query: 248 AASSEFYKDGK-YIVSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMITREL 306
           AA++EF+ DG  Y+  G   T +++ E Y  L   YP+VSIEDP  E+DW+G+  +T  +
Sbjct: 242 AAATEFFTDGTGYVFEGTTRTADQMTEFYAGLLGAYPLVSIEDPLSEDDWDGWAALTASI 301

Query: 307 GKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYGVVV 366
           G +VQIVGDD+FVTNP+RL++GIE G ANALL+KVNQIGTLTE +DA  +A   GY  ++
Sbjct: 302 GDRVQIVGDDIFVTNPERLEEGIERGVANALLVKVNQIGTLTETLDAVTLAHHGGYRTMI 361

Query: 367 SHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAG 422
           SHRSGETED  IADLAVA+ +GQIKTGAPARS+R AKYNQL+RIEE L   A YAG
Sbjct: 362 SHRSGETEDTMIADLAVAIGSGQIKTGAPARSERVAKYNQLLRIEEALGDAARYAG 417


>emb|CAB94910.1| (AJ401152) enolase [Enterococcus faecalis]
           Length = 432
           
 Score =  487 bits (1241), Expect = e-137
 Identities = 253/421 (60%), Positives = 318/421 (75%), Gaps = 9/421 (2%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRDGGK-RYHGKG 66
           I  + ARE+LDSRGNPT+EV+V+T   + GR  VPSGASTG +EAVELRDG K RY GKG
Sbjct: 4   ITDIYAREVLDSRGNPTIEVEVYTESGAFGRGMVPSGASTGEYEAVELRDGDKARYLGKG 63

Query: 67  VRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAA 126
           V +AV+NVN IIA  ++G DVR Q  ID+ +I+LDGT NK  LGANAIL VS+AVA+AAA
Sbjct: 64  VTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIDLDGTPNKGKLGANAILGVSIAVARAAA 123

Query: 127 NALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVS 186
           + LE+PLY YLGG N  VLP P+ N+INGG HA N +DFQEFMIMP+GA +F+EA+R  +
Sbjct: 124 DYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSIDFQEFMIMPVGAPTFKEALRMGA 183

Query: 187 ETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALAL 246
           E +H L  ++  K    A +VGDEGGFAP +    E  +V+I+AIE+AGY PG+++ LA+
Sbjct: 184 EVFHALASIL--KGRGLATSVGDEGGFAPNLGSNEEGFEVIIEAIEKAGYVPGKDVVLAM 241

Query: 247 DAASSEFY--KDGKYIVSGK---EYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVM 301
           DAASSEFY  + G Y+++     E T EE++  Y+EL S YPI+SIED   E DW+GF  
Sbjct: 242 DAASSEFYDKEKGVYVLADSGEGEKTTEEMIAFYEELVSKYPIISIEDGLDENDWDGFKK 301

Query: 302 ITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAG 361
           +T  LG KVQ+VGDDLFVTN  +L +GIE G AN++L+KVNQIGTLTE  +A  MA  AG
Sbjct: 302 LTEVLGDKVQLVGDDLFVTNTTKLAEGIEKGIANSILIKVNQIGTLTETFEAIEMAKEAG 361

Query: 362 YGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYA 421
           Y  VVSHRSGETED+TI+D+AVA NAGQIKTG+ +R+DR AKYNQL+RIE++L  VA Y 
Sbjct: 362 YTAVVSHRSGETEDSTISDIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDQLGDVAEYK 421

Query: 422 G 422
           G
Sbjct: 422 G 422


>dbj|BAB07786.1| (AB046715) enolase [Desulfovibrio vulgaris]
           Length = 434
           
 Score =  486 bits (1237), Expect = e-136
 Identities = 253/418 (60%), Positives = 319/418 (75%), Gaps = 6/418 (1%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPIS-MGRAAVPSGASTGTHEAVELRDGGK-RYHGKG 66
           IV+V AREILDSRGNPTVEV+V       GRAAVPSGASTG+ EA+E+RDG K RY GKG
Sbjct: 4   IVSVWAREILDSRGNPTVEVEVSLESGHTGRAAVPSGASTGSREALEMRDGDKGRYKGKG 63

Query: 67  VRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAA 126
           V +AV+NV   IA  +VG+D   Q ++D  L++LDGT+NKS LGANA+L VSLA A+AA+
Sbjct: 64  VEKAVDNVMGEIAEAIVGLDSLRQVQVDNTLLDLDGTDNKSRLGANAMLGVSLATARAAS 123

Query: 127 NALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVS 186
           + L LPLYQYLGGVNA VLPVPL N+INGG HA N+LD QEFMIMPIGA +FR+A+R  +
Sbjct: 124 SFLGLPLYQYLGGVNAKVLPVPLMNIINGGAHAPNNLDIQEFMIMPIGAATFRDALRMGA 183

Query: 187 ETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALAL 246
           ET+H LK ++A     +  +VGDEGGFAP +K   E    ++KAIEEAGY PG EIALA+
Sbjct: 184 ETFHTLKALLAAD--GHVTSVGDEGGFAPNLKNHDEAFRYIMKAIEEAGYIPGAEIALAI 241

Query: 247 DAASSEFYKDGKYIVSG--KEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMITR 304
           DAA+SEF+KDGKY+++G  K  +  E++E   E T+ YP++SIED   E DW+G+  +T 
Sbjct: 242 DAAASEFHKDGKYVLAGEGKNLSNSEMVEWLGEFTTRYPLISIEDGLAEADWDGWRELTY 301

Query: 305 ELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYGV 364
           +LG  +Q+VGDD+FVTNP  L +GI+ G AN++L+K+NQIGTLTE +D   MA +A Y  
Sbjct: 302 KLGDTIQLVGDDIFVTNPDILAEGIDEGVANSILIKLNQIGTLTETLDTIEMAKQAAYTT 361

Query: 365 VVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAG 422
           V+SHRSGETED  I+DLAV LNAGQIKTG+  RSDR AKYNQL+RIEE+L+   +Y G
Sbjct: 362 VISHRSGETEDHFISDLAVGLNAGQIKTGSLCRSDRLAKYNQLLRIEEDLDDTGIYFG 419


>pir||A81841 phosphopyruvate hydratase (EC 4.2.1.11) NMA1495 [imported] -
           Neisseria meningitidis (group A strain Z2491)
           >gi|7380143|emb|CAB84728.1| (AL162756) enolase
           [Neisseria meningitidis Z2491]
           Length = 428
           
 Score =  481 bits (1225), Expect = e-135
 Identities = 259/419 (61%), Positives = 306/419 (72%), Gaps = 6/419 (1%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPIS-MGRAAVPSGASTGTHEAVELRDGGK-RYHGKG 66
           IV + AREILDSRGNPTVE DV      MGRAAVPSGASTG  EA+ELRDG K RY GKG
Sbjct: 4   IVDIFAREILDSRGNPTVECDVLLESGVMGRAAVPSGASTGQKEALELRDGDKSRYSGKG 63

Query: 67  VRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAA 126
           V +AVE+VN  IA  L+G+D   Q  ID+++IELDGTENK NLGANA LAVS+AVA+AAA
Sbjct: 64  VLKAVEHVNNQIAQALIGIDANEQSYIDQIMIELDGTENKGNLGANATLAVSMAVARAAA 123

Query: 127 NALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVS 186
               LPLY+YLGG     LPVP+ NVINGG HA N L+ QEFMIMP+GA SFREA+R  +
Sbjct: 124 EDSGLPLYRYLGGAGPMSLPVPMMNVINGGEHANNSLNIQEFMIMPVGAKSFREALRCGA 183

Query: 187 ETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALAL 246
           E +H LKK+   K       VGDEGGFAP +    E L ++++A E AGYK GE++  AL
Sbjct: 184 EIFHALKKLCDSK--GFPTTVGDEGGFAPNLNSHKEALQLMVEATEAAGYKAGEDVLFAL 241

Query: 247 DAASSEFYKDGKYIVS--GKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMITR 304
           D ASSEFYKDGKY +   G+ YT  E  E  + L + +PI+SIED   E DWEG+ ++T 
Sbjct: 242 DCASSEFYKDGKYHLEAEGRSYTNAEFAEYLEGLVNEFPIISIEDGMDENDWEGWKLLTE 301

Query: 305 ELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYGV 364
           +LG KVQ+VGDDLFVTNPK L +GIE G ANALL+KVNQIGTL+E + A  +A R  Y  
Sbjct: 302 KLGGKVQLVGDDLFVTNPKILAEGIEKGVANALLVKVNQIGTLSETLKAVDLAKRNRYAS 361

Query: 365 VVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAGK 423
           V+SHRSGETED+TIADLAVA N  QIKTG+ +RSDR AKYNQL+RIEEEL   A Y  K
Sbjct: 362 VMSHRSGETEDSTIADLAVATNCMQIKTGSLSRSDRMAKYNQLLRIEEELAEAADYPSK 420


>pir||D81100 enolase NMB1285 [imported] - Neisseria meningitidis (group B strain
           MD58) >gi|7226525|gb|AAF41661.1| (AE002477) enolase
           [Neisseria meningitidis MC58]
           Length = 428
           
 Score =  480 bits (1222), Expect = e-134
 Identities = 258/419 (61%), Positives = 306/419 (72%), Gaps = 6/419 (1%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPIS-MGRAAVPSGASTGTHEAVELRDGGK-RYHGKG 66
           IV + AREILDSRGNPTVE DV      MGRAAVPSGASTG  EA+ELRDG K RY GKG
Sbjct: 4   IVDIFAREILDSRGNPTVECDVLLESGVMGRAAVPSGASTGQKEALELRDGDKSRYSGKG 63

Query: 67  VRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAA 126
           V +AVE+VN  IA  L+G+D   Q  ID+++IELDGTENK NLGANA LAVS+AVA+AAA
Sbjct: 64  VLKAVEHVNNQIAQALIGIDANEQSYIDQIMIELDGTENKGNLGANATLAVSMAVARAAA 123

Query: 127 NALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVS 186
               LPLY+YLGG     LPVP+ NVINGG HA N L+ QEFMIMP+GA SFREA+R  +
Sbjct: 124 EDSGLPLYRYLGGAGPMSLPVPMMNVINGGEHANNSLNIQEFMIMPVGAKSFREALRCGA 183

Query: 187 ETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALAL 246
           E +H LKK+   K       VGDEGGFAP +    E L ++++A E AGYK GE++  AL
Sbjct: 184 EIFHALKKLCDSK--GFPTTVGDEGGFAPNLNSHKEALQLMVEATEAAGYKAGEDVLFAL 241

Query: 247 DAASSEFYKDGKYIVS--GKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMITR 304
           D ASSEFYKDGKY +   G+ YT  E  E  + L + +PI+SIED   E DWEG+ ++T 
Sbjct: 242 DCASSEFYKDGKYHLEAEGRSYTNAEFAEYLEGLVNEFPIISIEDGMDENDWEGWKLLTE 301

Query: 305 ELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYGV 364
           +LG +VQ+VGDDLFVTNPK L +GIE G ANALL+KVNQIGTL+E + A  +A R  Y  
Sbjct: 302 KLGGRVQLVGDDLFVTNPKILAEGIEKGVANALLVKVNQIGTLSETLKAVDLAKRNRYAS 361

Query: 365 VVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAGK 423
           V+SHRSGETED+TIADLAVA N  QIKTG+ +RSDR AKYNQL+RIEEEL   A Y  K
Sbjct: 362 VMSHRSGETEDSTIADLAVATNCMQIKTGSLSRSDRMAKYNQLLRIEEELAEAADYPSK 420


>sp|O51312|ENO_BORBU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|7436876|pir||H70141 enolase (eno)
           homolog - Lyme disease spirochete
           >gi|2688240|gb|AAC66719.1| (AE001140) enolase (eno)
           [Borrelia burgdorferi]
           Length = 433
           
 Score =  474 bits (1208), Expect = e-133
 Identities = 251/425 (59%), Positives = 314/425 (73%), Gaps = 9/425 (2%)

Query: 7   YEIVAVIAREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRDGGKR-YHG 64
           + I  + AR+I+DSRGNPTVE DV     + GRAAVPSGASTG +EAVELRDG K  Y G
Sbjct: 3   FHIYEIKARQIIDSRGNPTVEADVILEDGTYGRAAVPSGASTGINEAVELRDGDKSVYMG 62

Query: 65  KGVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKA 124
           KGV +A+EN+  IIAPEL GM    Q  IDR ++ELDGT  K  LGANAILAVS+A AKA
Sbjct: 63  KGVLKAIENIKNIIAPELEGMSALNQVAIDRKMLELDGTPTKEKLGANAILAVSMATAKA 122

Query: 125 AANALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRW 184
           AA  L L  YQYLG   A +LP P+ N+INGG H+ N +DFQEFMIMPIGA +F EAIR 
Sbjct: 123 AAKYLGLRPYQYLGAYKANILPTPMCNIINGGAHSDNSVDFQEFMIMPIGAKTFSEAIRM 182

Query: 185 VSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIAL 244
            +E +H LK +++ K    A +VGDEGGFAP +K   E  +V+I+AI++AGY+PG++IA+
Sbjct: 183 AAEVFHTLKGILSGK--GYATSVGDEGGFAPNLKSNEEACEVIIEAIKKAGYEPGKDIAI 240

Query: 245 ALDAASSEFY--KDGKYIV---SGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGF 299
           ALD A+SE Y  K  KY++   + ++ T E+++E + +    YPI+SIED   EEDW+G+
Sbjct: 241 ALDPATSELYDPKTKKYVLKWSTKEKLTSEQMVEYWAKWVEKYPIISIEDGMAEEDWDGW 300

Query: 300 VMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFR 359
             +T ++G K+Q+VGDDLFVTN   LKKGIEMG AN++L+KVNQIGTLTE  +A  MA +
Sbjct: 301 KKLTDKIGNKIQLVGDDLFVTNTSFLKKGIEMGVANSILIKVNQIGTLTETFEAVEMAKK 360

Query: 360 AGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAV 419
           AGY  +VSHRSGETED TIADL VAL  GQIKTG+ +R+DR AKYNQLIRIEEELE  A 
Sbjct: 361 AGYTAIVSHRSGETEDTTIADLVVALGTGQIKTGSLSRTDRIAKYNQLIRIEEELETTAE 420

Query: 420 YAGKN 424
           Y GK+
Sbjct: 421 YHGKS 425


>sp|P42894|ENO_NEOFR ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|515827|emb|CAA56645.1| (X80474) enolase
           [Neocallimastix frontalis]
           Length = 436
           
 Score =  474 bits (1206), Expect = e-132
 Identities = 258/436 (59%), Positives = 316/436 (72%), Gaps = 17/436 (3%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGKR-YHGKGV 67
           I  V AR+I DSRGNPTVEV+V T   + RAAVPSGASTG HEA+ELRDG K  Y GKGV
Sbjct: 3   ITKVHARQIFDSRGNPTVEVEVTTDKGLFRAAVPSGASTGVHEALELRDGIKADYVGKGV 62

Query: 68  RRAVENVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
            +AVENVNK IAP LV   +DV+ Q+ +D  L++LDGT NKS LGANAIL VSLAVA+A 
Sbjct: 63  LKAVENVNKTIAPALVAANLDVKNQKAVDDFLLKLDGTPNKSKLGANAILGVSLAVARAG 122

Query: 126 ANALELPLYQYLGGV----NAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREA 181
           A    +PLYQ+LG +      ++LPVP  NV+NGG HAGN L  QEFMI+P GA SF EA
Sbjct: 123 AADKGVPLYQHLGELAGNKGPWILPVPSMNVLNGGSHAGNKLAMQEFMILPTGAKSFTEA 182

Query: 182 IRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEE 241
           ++  SE YH LK VI  KYG++A NVGDEGGFAP +++  E L++L +AI +AGY    +
Sbjct: 183 LKMGSEVYHALKSVIKAKYGQDACNVGDEGGFAPNIQDNKEGLELLNEAIAKAGYTG--K 240

Query: 242 IALALDAASSEFYKDGKYIVSGKE--------YTREELLELYKELTSTYPIVSIEDPFHE 293
           + + +D ASSEFYKDGKY +  K          + EEL + YKE+TS YPIVSIEDP+ +
Sbjct: 241 VKIGMDVASSEFYKDGKYDLDFKNPNSDPSKWISGEELGQFYKEITSEYPIVSIEDPYDQ 300

Query: 294 EDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDA 353
           +D+E +     ++  K+QIVGDDL VTNPKR+   IE  A N LLLKVNQIGT++E++ A
Sbjct: 301 DDFESWSKFRADMQDKIQIVGDDLTVTNPKRIAMAIEKKACNGLLLKVNQIGTVSESIQA 360

Query: 354 AYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEE 413
           A  AF  G+GV+VSHRSGETED  IADL V L +GQIKTGAP RS+R AKYNQL+RIEEE
Sbjct: 361 ALDAFNDGWGVMVSHRSGETEDTFIADLVVGLKSGQIKTGAPCRSERLAKYNQLLRIEEE 420

Query: 414 LEGVAVYAGKNFRKVF 429
           L   A YAG+NFR+ F
Sbjct: 421 LGANATYAGENFRRPF 436


>pir||T12341 phosphopyruvate hydratase (EC 4.2.1.11) - common ice plant
           >gi|533474|gb|AAA21277.1| (U09194) 2-phospho-D-glycerate
           hydrolase [Mesembryanthemum crystallinum]
           Length = 444
           
 Score =  473 bits (1205), Expect = e-132
 Identities = 258/438 (58%), Positives = 318/438 (71%), Gaps = 21/438 (4%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRDGGKRYHGKGV 67
           I  V AR+I DSRGNPTVE D+H    +  RAAVPSGASTG +EA+ELRDGGK Y GKGV
Sbjct: 4   IKCVKARQIYDSRGNPTVEADIHLDDGTYARAAVPSGASTGVYEALELRDGGKDYMGKGV 63

Query: 68  RRAVENVNKIIAPELVGMDVRWQREIDRLLIE-LDGTEN-----KSNLGANAILAVSLAV 121
            +AV+NVN+II P LVG D   Q  ID  +++ LDGT N     K  LGANAILAVSLAV
Sbjct: 64  YKAVKNVNEIIGPALVGKDPTQQTAIDNFMVQQLDGTVNEWGWCKQKLGANAILAVSLAV 123

Query: 122 AKAAANALELPLYQYLG---GVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSF 178
            KA A   ++PLYQ++    G    VLPVP  NVINGG HAGN L  QEFMI+P GA+SF
Sbjct: 124 CKAGAQVKKIPLYQHIAEIAGNKNMVLPVPAFNVINGGSHAGNKLAMQEFMILPTGASSF 183

Query: 179 REAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKP 238
           +EA++  SE YH LK VI +KYG++A NVGDEGGFAP ++E  E L++L  AIE+AGY  
Sbjct: 184 KEAMKMGSEVYHNLKSVIKKKYGQDATNVGDEGGFAPNIQENKEGLELLKTAIEKAGYTG 243

Query: 239 GEEIALALDAASSEFYKDGK-YIVSGKEYTR--------EELLELYKELTSTYPIVSIED 289
             ++ + +D A+SEFYK+ K Y ++ KE           E L +LYK   + YPIVSIED
Sbjct: 244 --KVVIGMDVAASEFYKEDKSYDLNFKEENNDGSQRISGEALKDLYKSFVAEYPIVSIED 301

Query: 290 PFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTE 349
           PF ++DWE +  +T E G+KVQIVGDDL VTNPKR+KK I+  + NALLLKVNQIG++TE
Sbjct: 302 PFDQDDWEHYAKMTAECGEKVQIVGDDLLVTNPKRVKKAIDENSCNALLLKVNQIGSVTE 361

Query: 350 AMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIR 409
           +++A  M+ +AG+GV+ SHRSGETED  IADL+V L+ GQIKTGAP RS+R AKYNQL+R
Sbjct: 362 SIEAVKMSKKAGWGVMASHRSGETEDTFIADLSVGLSTGQIKTGAPCRSERLAKYNQLLR 421

Query: 410 IEEELEGVAVYAGKNFRK 427
           IEEEL   AVYAG NFR+
Sbjct: 422 IEEELGDKAVYAGANFRR 439


>sp|Q43130|ENO_MESCR ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|1087071|gb|AAB34986.1| (S79242)
           2-phospho-D-glycerate hydrolase, enolase {EC 4.2.1.11}
           [Mesembryanthemum crystallinum=common ice plant,
           Peptide, 444 aa]
           Length = 444
           
 Score =  473 bits (1203), Expect = e-132
 Identities = 258/438 (58%), Positives = 317/438 (71%), Gaps = 21/438 (4%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRDGGKRYHGKGV 67
           I  V AR+I DSRGNPTVE D+H    +  RAAVPSGASTG +EA+ELRDGGK Y GKGV
Sbjct: 4   IKCVKARQIYDSRGNPTVEADIHLDDGTYARAAVPSGASTGVYEALELRDGGKDYMGKGV 63

Query: 68  RRAVENVNKIIAPELVGMDVRWQREIDRLLIE-LDGTEN-----KSNLGANAILAVSLAV 121
            +AV+NVN+II P LVG D   Q  ID  +++ LDGT N     K  LGANAILAVSLAV
Sbjct: 64  YKAVKNVNEIIGPALVGKDPTQQTAIDNFMVQQLDGTVNEWGWCKQKLGANAILAVSLAV 123

Query: 122 AKAAANALELPLYQYLG---GVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSF 178
            KA A   ++PLYQ++    G    VLPVP  NVINGG HAGN L  QEFMI+P GA+SF
Sbjct: 124 CKAGAQVKKIPLYQHIAEIAGNKNMVLPVPAFNVINGGSHAGNKLAMQEFMILPTGASSF 183

Query: 179 REAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKP 238
           +EA++  SE YH LK VI +KYG++A NVGDEGGFAP ++E  E L++L  AIE+AGY  
Sbjct: 184 KEAMKMGSEVYHNLKSVIKKKYGQDATNVGDEGGFAPNIQENKEGLELLKTAIEKAGYTG 243

Query: 239 GEEIALALDAASSEFYKDGK-YIVSGKEYTR--------EELLELYKELTSTYPIVSIED 289
             ++ + +D A+SEFYK+ K Y ++ KE           E L +LYK   + YPIVSIED
Sbjct: 244 --KVVIGMDVAASEFYKEDKSYDLNFKEENNDGSQRISGEALKDLYKSFVAEYPIVSIED 301

Query: 290 PFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTE 349
           PF ++DWE +  +T E G+KVQIVGDDL VTNPKR+KK I+    NALLLKVNQIG++TE
Sbjct: 302 PFDQDDWEHYAKMTAECGEKVQIVGDDLLVTNPKRVKKAIDENPCNALLLKVNQIGSVTE 361

Query: 350 AMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIR 409
           +++A  M+ +AG+GV+ SHRSGETED  IADL+V L+ GQIKTGAP RS+R AKYNQL+R
Sbjct: 362 SIEAVKMSKKAGWGVMASHRSGETEDTFIADLSVGLSTGQIKTGAPCRSERLAKYNQLLR 421

Query: 410 IEEELEGVAVYAGKNFRK 427
           IEEEL   AVYAG NFR+
Sbjct: 422 IEEELGDKAVYAGANFRR 439


>gb|AAC46289.1| (AF000366) enolase homolog [Borrelia burgdorferi]
           Length = 433
           
 Score =  473 bits (1203), Expect = e-132
 Identities = 250/425 (58%), Positives = 313/425 (72%), Gaps = 9/425 (2%)

Query: 7   YEIVAVIAREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRDGGKR-YHG 64
           + I  + AR+I+DSRGNPTVE DV     + GRAAVPSGASTG +EAVELRDG K  Y G
Sbjct: 3   FHIYEIKARQIIDSRGNPTVEADVILEDGTYGRAAVPSGASTGINEAVELRDGDKSVYMG 62

Query: 65  KGVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKA 124
           KGV +A+EN+  IIAPEL GM    Q  IDR ++ELDGT  K  LGANAILAVS+A AKA
Sbjct: 63  KGVLKAIENIKNIIAPELEGMSALNQVAIDRKMLELDGTPTKEKLGANAILAVSMATAKA 122

Query: 125 AANALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRW 184
           AA  L L  YQYLG   A +LP P+ N+INGG H+ N +DFQEFMIMPIGA +F EAIR 
Sbjct: 123 AAKYLGLRPYQYLGAYKANILPTPMCNIINGGAHSDNSVDFQEFMIMPIGAKTFSEAIRM 182

Query: 185 VSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIAL 244
            +E +H LK +++ K    A +VGDEGGFAP +K   E  +V+I+AI++AGY+PG++IA+
Sbjct: 183 AAEVFHTLKGILSGK--GYATSVGDEGGFAPNLKSNEEACEVIIEAIKKAGYEPGKDIAI 240

Query: 245 ALDAASSEFY--KDGKYIV---SGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGF 299
           ALD A+SE Y  K  KY++   + ++ T E+++E + +    YPI+SIED   EEDW+G+
Sbjct: 241 ALDPATSELYDPKTKKYVLKWSTKEKLTSEQMVEYWAKWVEKYPIISIEDGMAEEDWDGW 300

Query: 300 VMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFR 359
             +T ++G K+Q+VGDDLFVTN   LKKGIEMG AN++L+KVNQIGTLTE  +A  MA +
Sbjct: 301 KKLTDKIGNKIQLVGDDLFVTNTSFLKKGIEMGVANSILIKVNQIGTLTETFEAVEMAKK 360

Query: 360 AGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAV 419
           AGY  +VSHRSGETED TIADL VAL  GQ KTG+ +R+DR AKYNQLIRIEEELE  A 
Sbjct: 361 AGYTAIVSHRSGETEDTTIADLVVALGTGQTKTGSLSRTDRIAKYNQLIRIEEELETTAE 420

Query: 420 YAGKN 424
           Y GK+
Sbjct: 421 YHGKS 425


>emb|CAB75428.1| (AJ271785) enolase [Lupinus luteus]
           Length = 444
           
 Score =  473 bits (1203), Expect = e-132
 Identities = 257/437 (58%), Positives = 322/437 (72%), Gaps = 21/437 (4%)

Query: 9   IVAVIAREILDSRGNPTVEVDVH-TPISMGRAAVPSGASTGTHEAVELRDGGKRYHGKGV 67
           I  + AR+I DSRGNPTVEVD+  +  +  RAAVPSGASTG +EA+ELRDGG  Y GKGV
Sbjct: 4   IATIKARQIFDSRGNPTVEVDLTLSDGTFARAAVPSGASTGIYEALELRDGGSDYLGKGV 63

Query: 68  RRAVENVNKIIAPELVGMDVRWQREIDRLLI-ELDGTEN-----KSNLGANAILAVSLAV 121
            +AV+NVN IIAP L+G D   Q  ID  ++ ELDGT N     K  LGANAILAVSLAV
Sbjct: 64  SKAVDNVNTIIAPALIGKDPTEQTAIDNFIVQELDGTVNEWGWGKQKLGANAILAVSLAV 123

Query: 122 AKAAANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSF 178
            KA A+AL++PLY++   L G    VLPVP  NVINGG HAGN L  QEFMI+P+GA++F
Sbjct: 124 CKAGASALKIPLYKHIANLAGNKNLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASTF 183

Query: 179 REAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKP 238
           +EA++   E YH LK VI +KYG++AVNVGDEGGFAP ++E  E L++L  AI +AGY  
Sbjct: 184 KEALKIGVEVYHNLKSVIKKKYGQDAVNVGDEGGFAPNIQENKEGLELLKSAIAKAGYT- 242

Query: 239 GEEIALALDAASSEFY-KDGKYIVSGKE--------YTREELLELYKELTSTYPIVSIED 289
            +++ + +D A+SEFY  D KY+++ KE         + EEL ELYK   + YPI SIED
Sbjct: 243 -DKVVIGMDVAASEFYTSDKKYVLNFKEDNNDGSQKISGEELKELYKSFVAEYPIASIED 301

Query: 290 PFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTE 349
           PF ++DWE +  IT E+G +VQIVGDDL VTNPKR++K I+  + NALLLKVNQIG++TE
Sbjct: 302 PFDQDDWEHYGKITTEIGTEVQIVGDDLLVTNPKRVQKAIDSKSCNALLLKVNQIGSVTE 361

Query: 350 AMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIR 409
           +++A  M+ +AG+GV+ SHRSGETED  IADLAV L+ GQIKTGAP RS+R AKYNQL+R
Sbjct: 362 SIEAVKMSKKAGWGVMTSHRSGETEDTFIADLAVGLSTGQIKTGAPCRSERLAKYNQLLR 421

Query: 410 IEEELEGVAVYAGKNFR 426
           IEEEL   AVYAG N+R
Sbjct: 422 IEEELGDEAVYAGVNYR 438


>emb|CAB96173.1| (AJ271719) enolase [Spinacia oleracea]
           Length = 444
           
 Score =  469 bits (1193), Expect = e-131
 Identities = 256/437 (58%), Positives = 317/437 (71%), Gaps = 21/437 (4%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRDGGKRYHGKGV 67
           I +V AR+I DSRGNPTVE D+H    +  RAAVPSGASTG +EA+ELRDGGK Y GKGV
Sbjct: 4   IKSVKARQIFDSRGNPTVEADIHLDDGTFARAAVPSGASTGIYEALELRDGGKDYMGKGV 63

Query: 68  RRAVENVNKIIAPELVGMDVRWQREIDRLLI-ELDGTEN-----KSNLGANAILAVSLAV 121
            +AV+NVN+II P LVG D   Q  ID  ++ ELDGT N     K  LGANAILAVSLAV
Sbjct: 64  FKAVQNVNEIIGPALVGKDPTEQTAIDNFMVQELDGTTNEWGWCKQKLGANAILAVSLAV 123

Query: 122 AKAAANALELPLYQYLGGVNA---YVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSF 178
            KA A   ++PLYQ++  ++     VLPVP  NVINGG HAGN L  QEFMI+P GA+SF
Sbjct: 124 CKAGAQVKKIPLYQHIAEISGNKKMVLPVPAFNVINGGSHAGNKLAMQEFMILPTGASSF 183

Query: 179 REAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKP 238
           REA++  SE YH LK VI +KYG++A NVGDEGGFAP ++E  E L++L  AIE+AGY  
Sbjct: 184 REAMKMGSEVYHHLKSVIKKKYGQDATNVGDEGGFAPNIQENKEGLELLKTAIEKAGYTG 243

Query: 239 GEEIALALDAASSEFY-KDGKYIVSGKEYTRE--------ELLELYKELTSTYPIVSIED 289
             ++ + +D A++EFY KD  Y ++ KE   +         L +LYK   S YPIVSIED
Sbjct: 244 --KVVIGMDVAAAEFYSKDKTYDLNFKEENNDGSQKISGDALKDLYKSFVSEYPIVSIED 301

Query: 290 PFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTE 349
           PF ++DWE +  +T E+G KVQIVGDDL VTNPKR++K I   + NALLLKVNQIG++TE
Sbjct: 302 PFDQDDWEHYGKLTAEIGDKVQIVGDDLLVTNPKRVEKAINGKSCNALLLKVNQIGSVTE 361

Query: 350 AMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIR 409
           +++A  M+ RAG+GV+ SHRSGETED  IADL+V L+ GQIKTGAP RS+R AKYNQL+R
Sbjct: 362 SIEAVKMSKRAGWGVMASHRSGETEDTFIADLSVGLSTGQIKTGAPCRSERLAKYNQLLR 421

Query: 410 IEEELEGVAVYAGKNFR 426
           IEEEL   A+YAG +FR
Sbjct: 422 IEEELGDKAIYAGADFR 438


>sp|P77972|ENO_SYNY3 ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|7436879|pir||S76837 phosphopyruvate
           hydratase (EC 4.2.1.11) - Synechocystis sp.  (strain PCC
           6803) >gi|1653839|dbj|BAA18749.1| (D90917) enolase
           [Synechocystis sp.]
           Length = 432
           
 Score =  468 bits (1191), Expect = e-131
 Identities = 244/425 (57%), Positives = 310/425 (72%), Gaps = 3/425 (0%)

Query: 1   MTMENPYEIVAVIAREILDSRGNPTVEVDVHTPISM-GRAAVPSGASTGTHEAVELRDGG 59
           M  + P  I  + AREILDSRG PT+E +V       G A VPSGASTG+ EA ELRDG 
Sbjct: 1   MLSKVPATIEEIAAREILDSRGRPTIEAEVRLESGAHGIAQVPSGASTGSFEAHELRDGD 60

Query: 60  -KRYHGKGVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVS 118
            KRY GKGV +AV NV + IAP + G+D   Q  +D+ +I+ DGT+NK  LGANAIL VS
Sbjct: 61  PKRYDGKGVEKAVRNVTEKIAPVVEGLDAFDQMAVDQAMIDRDGTDNKKELGANAILGVS 120

Query: 119 LAVAKAAANALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSF 178
           LA AKAAA  L +PLY+YLGG  A VLPVP+ NVINGG HA N++DFQEFMIMP+GA +F
Sbjct: 121 LATAKAAAAELAIPLYRYLGGPLANVLPVPMMNVINGGAHADNNVDFQEFMIMPVGAETF 180

Query: 179 REAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKP 238
           +EA+RW +E + VL KV+ E+   +   VGDEGG+AP +    + LD+LI+AIE+AGYKP
Sbjct: 181 KEALRWGAEVFAVLGKVLKERKLLSG-GVGDEGGYAPNLTSNQQALDILIEAIEQAGYKP 239

Query: 239 GEEIALALDAASSEFYKDGKYIVSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEG 298
           G +IALA+D A+SEF+K+G+Y   G  ++ +E ++   +L S YPIVSIED  HE+DWE 
Sbjct: 240 GSQIALAMDIAASEFFKNGQYEYDGGSHSPQEFIDYQAKLVSQYPIVSIEDGLHEDDWES 299

Query: 299 FVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAF 358
           +  +T  LG K Q+VGDDL VTNP RL+K I++G ANA+L+K+NQIGTL+E ++   +A 
Sbjct: 300 WKGLTTSLGTKTQLVGDDLMVTNPVRLQKSIDLGVANAILIKLNQIGTLSETLETISLAT 359

Query: 359 RAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVA 418
           R  Y  V+SHRSGETED TIADLAVA   GQIKTG+  RS+R AKYN+L+RIE+EL   A
Sbjct: 360 RHSYRSVISHRSGETEDTTIADLAVATRVGQIKTGSLCRSERVAKYNRLLRIEDELGDRA 419

Query: 419 VYAGK 423
           VYA K
Sbjct: 420 VYAPK 424


>sp|P74934|ENO_TREPA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|7436871|pir||F71278 probable enolase
           (eno) - syphilis spirochete >gi|1575361|gb|AAB39979.1|
           (U61534) 2-phospho-D-glycerate hydrolase [Treponema
           pallidum] >gi|3323125|gb|AAC65781.1| (AE001252) enolase
           (eno) [Treponema pallidum]
           Length = 432
           
 Score =  467 bits (1190), Expect = e-131
 Identities = 250/430 (58%), Positives = 320/430 (74%), Gaps = 13/430 (3%)

Query: 8   EIVAVIAREILDSRGNPTVEVDVH-TPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGK 65
           +I  + AREI+DSRGNPTVEVDV  +  S GRA VPSGASTG  EA+E+RDG K RY+GK
Sbjct: 3   DIACIEAREIIDSRGNPTVEVDVSLSDGSFGRACVPSGASTGEFEALEMRDGDKERYNGK 62

Query: 66  GVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
           GV +AV  VN +IA  L GMD   Q EID  +  LDGT+NKS LGANA+L VS+A A+AA
Sbjct: 63  GVLKAVGTVNTLIADTLEGMDALNQGEIDHAMRNLDGTDNKSKLGANAMLGVSMACARAA 122

Query: 126 ANALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWV 185
           A+ L +PLY+YLGGV+ + +PVP++N+INGG H+ N +DFQEFM+MPIGA S REA+R  
Sbjct: 123 ADFLGVPLYRYLGGVHTFRMPVPMANIINGGKHSDNKIDFQEFMVMPIGAASMREAVRMT 182

Query: 186 SETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALA 245
           +E +H LK ++A   GK A +VGDEGGFAP +    + L+ ++KAI +AG  P +++ +A
Sbjct: 183 AEVFHALKGLLAAD-GK-ATSVGDEGGFAPDLDN-EQALEYIMKAIAKAGLAPRKDVCIA 239

Query: 246 LDAASSEFYKDG-----KYIVS--GKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEG 298
           LD ASSE + +G     K+  S  GK +T +E+++LYK+  +TYPIVSIEDP  + DW G
Sbjct: 240 LDCASSELFDEGDRRGYKFWKSNPGKLFTAQEMIDLYKKWIATYPIVSIEDPLDQNDWAG 299

Query: 299 FVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAF 358
           +V +T+ELG KVQIVGDD FVTN  RL +GI+ G+ N++L+K+NQIGT+TE +DA  MA 
Sbjct: 300 YVQLTKELGDKVQIVGDDFFVTNTGRLARGIKEGSCNSILIKLNQIGTVTETVDAVRMAQ 359

Query: 359 RAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVA 418
            AGY  V+SHRSGETEDA IADLAVAL  GQIKTG+ +RSDR AKYNQL+RIEEEL   A
Sbjct: 360 NAGYAAVISHRSGETEDAFIADLAVALETGQIKTGSMSRSDRVAKYNQLMRIEEELGAQA 419

Query: 419 VYAG-KNFRK 427
            Y G K F +
Sbjct: 420 RYYGAKTFER 429


>sp|O69174|ENO_STAAU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) (LAMININ BINDING PROTEIN)
           >gi|11268974|pir||T47276 phosphopyruvate hydratase (EC
           4.2.1.11) [imported] - Staphylococcus aureus
           >gi|3152725|gb|AAC17130.1| (AF065394) enolase
           [Staphylococcus aureus]
           Length = 434
           
 Score =  466 bits (1187), Expect = e-130
 Identities = 245/424 (57%), Positives = 311/424 (72%), Gaps = 12/424 (2%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRDGGK-RYHGKG 66
           I  V ARE+LDSRGNPTVEV+V T   + GRA VPSGASTG HEAVELRDG K RY GKG
Sbjct: 4   ITDVYAREVLDSRGNPTVEVEVLTESGAFGRALVPSGASTGEHEAVELRDGDKSRYLGKG 63

Query: 67  VRRAVENVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKA 124
           V +AVENVN+IIAPE++     V  Q  ID+++I LDGT NK  LGANAIL VS+AVA+A
Sbjct: 64  VTKAVENVNEIIAPEIIEGEFSVLDQVSIDKMMIALDGTPNKGKLGANAILGVSIAVARA 123

Query: 125 AANALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRW 184
           AA+ L  PLY+YLGG N   LPVP+ N++NGG H+   + FQEFMI+P+GA +F+E++RW
Sbjct: 124 AADLLGQPLYKYLGGFNGKQLPVPMMNIVNGGSHSDAPIAFQEFMILPVGATTFKESLRW 183

Query: 185 VSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIAL 244
            +E +H LK +++++  + AV  GDEGGFAP  +   + ++ +I+AIE AGYKPGEE+ L
Sbjct: 184 GTEIFHNLKSILSQRGLETAV--GDEGGFAPKFEGTEDAVETIIQAIEAAGYKPGEEVFL 241

Query: 245 ALDAASSEFYKDGKYIVS------GKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEG 298
             D ASSEFY++G Y  S      G + T  E ++  ++L   YPI++IED   E DW+G
Sbjct: 242 GFDCASSEFYENGVYDYSKFEGEHGAKRTAAEQVDYLEQLVDKYPIITIEDGMDENDWDG 301

Query: 299 FVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAF 358
           +  +T  +G +VQ+VGDDLFVTN + L KGIE G  N++L+KVNQIGTLTE  DA  MA 
Sbjct: 302 WKQLTERIGDRVQLVGDDLFVTNTEILAKGIENGIGNSILIKVNQIGTLTETFDAIEMAQ 361

Query: 359 RAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVA 418
           +AGY  VVSHRSGETED TIAD+AVA NAGQIKTG+ +R+DR AKYNQL+RIE+EL   A
Sbjct: 362 KAGYTAVVSHRSGETEDTTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDELFETA 421

Query: 419 VYAG 422
            Y G
Sbjct: 422 KYDG 425


>sp|P07323|ENOG_RAT GAMMA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (NEURAL ENOLASE)
           (NSE) >gi|92215|pir||A24742 phosphopyruvate hydratase
           (EC 4.2.1.11) gamma - rat >gi|204042|gb|AAA41119.1|
           (M11931) neuron-specific enolase [Rattus norvegicus]
           >gi|1619609|emb|CAA30556.1| (X07727) enol_cds [Rattus
           norvegicus] >gi|2465396|gb|AAB72088.1| (AF019973)
           neuron-specific enolase [Rattus norvegicus]
           >gi|225406|prf||1302225A enolase gamma,neuron specific
           [Rattus norvegicus]
           Length = 434
           
 Score =  466 bits (1186), Expect = e-130
 Identities = 250/431 (58%), Positives = 315/431 (73%), Gaps = 17/431 (3%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67
           I  + AREILDSRGNPTVEVD+HT   + RAAVPSGASTG +EA+ELRDG K RY GKGV
Sbjct: 3   IQKIWAREILDSRGNPTVEVDLHTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGV 62

Query: 68  RRAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
            +AV+++N  IAP L+  G+ V  Q ++D L++ELDGTENKS  GANAIL VSLAV KA 
Sbjct: 63  LKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAG 122

Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182
           A   +LPLY++   L G +  +LPVP  NVINGG HAGN L  QEFMI+P+GA SFR+A+
Sbjct: 123 AAEKDLPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAM 182

Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242
           R  +E YH LK VI +KYGK+A NVGDEGGFAP + E +E L+++ +AI++AGY   E++
Sbjct: 183 RLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYT--EKM 240

Query: 243 ALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEED 295
            + +D A+SEFY+DGKY +  K         T ++L  LY++    YP+VSIEDPF ++D
Sbjct: 241 VIGMDVAASEFYRDGKYDLDFKSPADPSRCITGDQLGALYQDFVRNYPVVSIEDPFDQDD 300

Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355
           W  +   T  +G  +QIVGDDL VTNPKR+++ +E  A N LLLKVNQIG++TEA+ A  
Sbjct: 301 WAAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACK 358

Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415
           +A   G+GV+VSHRSGETED  IADL V L  GQIKTGAP RS+R AKYNQL+RIEEEL 
Sbjct: 359 LAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELG 418

Query: 416 GVAVYAGKNFR 426
             A +AG NFR
Sbjct: 419 EEARFAGHNFR 429


>gi|5803011 enolase 2, (gamma, neuronal); Enolase-2, gamma, neuronal [Homo
           sapiens] >gi|11436317|ref|XP_006974.1| enolase 2,
           (gamma, neuronal) [Homo sapiens] >gi|68305|pir||NOHUG
           phosphopyruvate hydratase (EC 4.2.1.11) gamma - human
           >gi|31165|emb|CAA36215.1| (X51956) human gamma enolase
           [Homo sapiens] >gi|182116|gb|AAB59554.1| (M22349)
           enolase [Homo sapiens] >gi|1732416|gb|AAB51320.1|
           (U47924) neuron specific gamma-enolase [Homo sapiens]
           Length = 434
           
 Score =  466 bits (1186), Expect = e-130
 Identities = 251/431 (58%), Positives = 315/431 (72%), Gaps = 17/431 (3%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67
           I  + AREILDSRGNPTVEVD++T   + RAAVPSGASTG +EA+ELRDG K RY GKGV
Sbjct: 3   IEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGV 62

Query: 68  RRAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
            +AV+++N  IAP L+  G+ V  Q ++D L++ELDGTENKS  GANAIL VSLAV KA 
Sbjct: 63  LKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAG 122

Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182
           A   ELPLY++   L G +  +LPVP  NVINGG HAGN L  QEFMI+P+GA SFR+A+
Sbjct: 123 AAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAM 182

Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242
           R  +E YH LK VI +KYGK+A NVGDEGGFAP + E +E L+++ +AI++AGY   E+I
Sbjct: 183 RLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYT--EKI 240

Query: 243 ALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEED 295
            + +D A+SEFY+DGKY +  K         T ++L  LY++    YP+VSIEDPF ++D
Sbjct: 241 VIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDD 300

Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355
           W  +   T  +G  +QIVGDDL VTNPKR+++ +E  A N LLLKVNQIG++TEA+ A  
Sbjct: 301 WAAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACK 358

Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415
           +A   G+GV+VSHRSGETED  IADL V L  GQIKTGAP RS+R AKYNQL+RIEEEL 
Sbjct: 359 LAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELG 418

Query: 416 GVAVYAGKNFR 426
             A +AG NFR
Sbjct: 419 DEARFAGHNFR 429


>sp|P30575|ENO1_CANAL ENOLASE 1 (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|422073|pir||A40624 phosphopyruvate
           hydratase (EC 4.2.1.11) - yeast (Candida albicans)
           >gi|170861|gb|AAB46358.1| (L04943) enolase [Candida
           albicans] >gi|170863|gb|AAA71939.1| (L10290) enolase
           [Candida albicans] >gi|170865|gb|AAA34341.1| (M93712)
           enolase [Candida albicans]
           Length = 440
           
 Score =  466 bits (1185), Expect = e-130
 Identities = 251/430 (58%), Positives = 313/430 (72%), Gaps = 18/430 (4%)

Query: 14  AREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRAVE 72
           AR + DSRGNPTVEVD  T   + R+ VPSGASTG HEA+ELRDG K ++ GKGV +AV 
Sbjct: 9   ARYVYDSRGNPTVEVDFTTDKGLFRSIVPSGASTGVHEALELRDGDKSKWLGKGVLKAVA 68

Query: 73  NVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANALE 130
           NVN IIAP L+   +DV  Q +ID  L+ LDGT NKS LGANAIL VSLA A AAA A  
Sbjct: 69  NVNDIIAPALIKAKIDVVDQAKIDEFLLSLDGTPNKSKLGANAILGVSLAAANAAAAAQG 128

Query: 131 LPLYQYLGGVN-----AYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWV 185
           +PLY+++  ++      +VLPVP  NV+NGG HAG  L FQEFMI P G ++F EA+R  
Sbjct: 129 IPLYKHIANISNAKKGKFVLPVPFQNVLNGGSHAGGALAFQEFMIAPTGVSTFSEALRIG 188

Query: 186 SETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALA 245
           SE YH LK +  +KYG++A NVGDEGG AP +K   E LD+++ AI++AGYK   ++ +A
Sbjct: 189 SEVYHNLKSLTKKKYGQSAGNVGDEGGVAPDIKTPKEALDLIMDAIDKAGYKG--KVGIA 246

Query: 246 LDAASSEFYKDGKYIVSGKEYTRE--------ELLELYKELTSTYPIVSIEDPFHEEDWE 297
           +D ASSEFYKDGKY +  K    +        +L +LY++L S YPIVSIEDPF E+DW+
Sbjct: 247 MDVASSEFYKDGKYDLDFKNPESDPSKWLSGPQLADLYEQLISEYPIVSIEDPFAEDDWD 306

Query: 298 GFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMA 357
            +V     +G K+QIVGDDL VTNP R+K  IE  AANALLLKVNQIGTLTE++ AA  +
Sbjct: 307 AWVHFFERVGDKIQIVGDDLTVTNPTRIKTAIEKKAANALLLKVNQIGTLTESIQAANDS 366

Query: 358 FRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGV 417
           + AG+GV+VSHRSGETED  IADL+V L +GQIKTGAPARS+R AK NQ++RIEEEL   
Sbjct: 367 YAAGWGVMVSHRSGETEDTFIADLSVGLRSGQIKTGAPARSERLAKLNQILRIEEELGSE 426

Query: 418 AVYAGKNFRK 427
           A+YAGK+F+K
Sbjct: 427 AIYAGKDFQK 436


>sp|Q27727|ENO_PLAFA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|542426|pir||S42206 phosphopyruvate
           hydratase (EC 4.2.1.11) - malaria parasite  (Plasmodium
           falciparum) >gi|392027|gb|AAA18634.1| (U00152) enolase
           [Plasmodium falciparum]
           Length = 446
           
 Score =  465 bits (1184), Expect = e-130
 Identities = 249/440 (56%), Positives = 321/440 (72%), Gaps = 24/440 (5%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67
           I  + AREILDSRGNPTVEVD+ T + + RAAVPSGASTG +EA+ELRD  K RY GKGV
Sbjct: 5   ITRINAREILDSRGNPTVEVDLETNLGIFRAAVPSGASTGIYEALELRDNDKSRYLGKGV 64

Query: 68  RRAVENVNKIIAPELVGMDVRWQREIDRLLIE-LDGTEN-----KSNLGANAILAVSLAV 121
           ++A++N+N+IIAP+L+GM+   Q++ID L++E LDG++N     KS LGANAILA+S+AV
Sbjct: 65  QKAIKNINEIIAPKLIGMNCTEQKKIDNLMVEELDGSKNEWGWSKSKLGANAILAISMAV 124

Query: 122 AKAAANALELPLYQYLGGV-----NAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGAN 176
            +A A   ++ LY+YL  +     +  VLPVP  NVINGG HAGN L FQEFMI+P+GA 
Sbjct: 125 CRAGAAPNKVSLYKYLAQLAGKKSDQMVLPVPCLNVINGGSHAGNKLSFQEFMIVPVGAP 184

Query: 177 SFREAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGY 236
           SF+EA+R+ +E YH LK  I +KYG +A NVGDEGGFAP +    E LD+L+ AI+ AGY
Sbjct: 185 SFKEALRYGAEVYHTLKSEIKKKYGIDATNVGDEGGFAPNILNANEALDLLVTAIKSAGY 244

Query: 237 KPGEEIALALDAASSEFYK--------DGKYIVSGKEY--TREELLELYKELTSTYPIVS 286
           +   ++ +A+D A+SEFY         D K   + K    T  +L++LY +L   YPIVS
Sbjct: 245 EG--KVKIAMDVAASEFYNSENKTYDLDFKTPNNDKSLVKTGAQLVDLYIDLVKKYPIVS 302

Query: 287 IEDPFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGT 346
           IEDPF ++DWE +  +T  +GK VQIVGDDL VTNP R+ K +E  A NALLLKVNQIG+
Sbjct: 303 IEDPFDQDDWENYAKLTAAIGKDVQIVGDDLLVTNPTRITKALEKNACNALLLKVNQIGS 362

Query: 347 LTEAMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQ 406
           +TEA++A  ++ +  +GV+VSHRSGETED  IADL VAL  GQIKTGAP RS+RNAKYNQ
Sbjct: 363 ITEAIEACLLSQKNNWGVMVSHRSGETEDVFIADLVVALRTGQIKTGAPCRSERNAKYNQ 422

Query: 407 LIRIEEELEGVAVYAGKNFR 426
           L+RIEE L   AV+AG+ FR
Sbjct: 423 LLRIEESLGNNAVFAGEKFR 442


>emb|CAA31512.1| (X13120) neurone-specific enolase [Homo sapiens]
           >gi|930101|emb|CAA32505.1| (X14327) gamma enolase [Homo
           sapiens]
           Length = 433
           
 Score =  465 bits (1183), Expect = e-130
 Identities = 250/431 (58%), Positives = 315/431 (73%), Gaps = 17/431 (3%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67
           I  + AREILDSRGNPTVEVD++T   + RAAVPSGASTG +EA+ELRDG K RY GKGV
Sbjct: 2   IQKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGV 61

Query: 68  RRAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
            +AV+++N  IAP L+  G+ V  Q ++D L++ELDGTENKS  GANAIL VSLAV KA 
Sbjct: 62  LKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAG 121

Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182
           A   ELPLY++   L G +  +LPVP  NVINGG HAGN L  QEFMI+P+GA SFR+A+
Sbjct: 122 AAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAM 181

Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242
           R  +E YH LK VI +KYGK+A NVGDEGGFAP + E +E L+++ +AI++AGY   E++
Sbjct: 182 RLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYT--EKM 239

Query: 243 ALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEED 295
            + +D A+SEFY+DGKY +  K         T ++L  LY++    YP+VSIEDPF ++D
Sbjct: 240 VIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDD 299

Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355
           W  +   T  +G  +QIVGDDL VTNPKR+++ +E  A N LLLKVNQIG++TEA+ A  
Sbjct: 300 WAAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACK 357

Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415
           +A   G+GV+VSHRSGETED  IADL V L  GQIKTGAP RS+R AKYNQL+RIEEEL 
Sbjct: 358 LAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELG 417

Query: 416 GVAVYAGKNFR 426
             A +AG NFR
Sbjct: 418 DEARFAGHNFR 428


>sp|P26300|ENO_LYCES ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|82082|pir||JQ1185 phosphopyruvate
           hydratase (EC 4.2.1.11) - tomato
           >gi|19281|emb|CAA41115.1| (X58108) enolase [Lycopersicon
           esculentum]
           Length = 444
           
 Score =  465 bits (1183), Expect = e-130
 Identities = 257/440 (58%), Positives = 317/440 (71%), Gaps = 25/440 (5%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMG---RAAVPSGASTGTHEAVELRDGGKRYHGK 65
           I ++ AR+I DSRGNPTVEVDVH  IS G   RAAVPSGASTG +EA+ELRDGG  Y GK
Sbjct: 4   IKSIKARQIFDSRGNPTVEVDVH--ISNGVFARAAVPSGASTGIYEALELRDGGSDYLGK 61

Query: 66  GVRRAVENVNKIIAPELVGMDVRWQREIDRLLI-ELDGTEN-----KSNLGANAILAVSL 119
           GV +AV NVN II P LVG D   Q  +D  ++ +LDGT+N     K  LGANAILAVSL
Sbjct: 62  GVSKAVNNVNSIIGPALVGKDPTDQTGLDNFMVHQLDGTQNEWGWCKEKLGANAILAVSL 121

Query: 120 AVAKAAANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGAN 176
           AV KA A    +PLY++   L G    VLPVP  NVINGG HAGN L  QEFMI+P+GA 
Sbjct: 122 AVCKAGAAVRNVPLYKHIADLAGNKKLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGAA 181

Query: 177 SFREAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGY 236
           +F+EA++   E YH LK VI +KYG++A NVGDEGGFAP ++E  E L++L  AIE+AGY
Sbjct: 182 NFKEAMKMGCEVYHHLKAVIKKKYGQDATNVGDEGGFAPNIQENKEGLELLKTAIEKAGY 241

Query: 237 KPGEEIALALDAASSEFY-KDGKYIVSGKEYTRE--------ELLELYKELTSTYPIVSI 287
               ++ + +D A+SEFY KD  Y ++ KE + +        +L +LYK   S YPIVSI
Sbjct: 242 TG--KVVIGMDVAASEFYGKDKSYDLNFKEESNDGSQKISGDQLKDLYKSFVSEYPIVSI 299

Query: 288 EDPFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTL 347
           EDPF ++DWE +  +T E+G++VQIVGDDL VTNPKR+ K I     NALLLKVNQIG++
Sbjct: 300 EDPFDQDDWETYAKLTAEIGEQVQIVGDDLLVTNPKRVAKAIAEKTCNALLLKVNQIGSV 359

Query: 348 TEAMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQL 407
           TE+++A  M+ +AG+GV+ SHRSGETED  IADLAV L+ GQIKTGAP RS+R AKYNQL
Sbjct: 360 TESIEAVKMSKKAGWGVMTSHRSGETEDTFIADLAVGLSTGQIKTGAPCRSERLAKYNQL 419

Query: 408 IRIEEELEGVAVYAGKNFRK 427
           +RIEEEL   AVYAG +FRK
Sbjct: 420 LRIEEELGSEAVYAGASFRK 439


>sp|P09104|ENOG_HUMAN GAMMA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (NEURAL ENOLASE)
           (NSE)
           Length = 434
           
 Score =  465 bits (1183), Expect = e-130
 Identities = 250/431 (58%), Positives = 315/431 (73%), Gaps = 17/431 (3%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67
           I  + AREILDSRGNPTVEVD++T   + RAAVPSGASTG +EA+ELRDG K RY GKGV
Sbjct: 3   IQKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGV 62

Query: 68  RRAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
            +AV+++N  IAP L+  G+ V  Q ++D L++ELDGTENKS  GANAIL VSLAV KA 
Sbjct: 63  LKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAG 122

Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182
           A   ELPLY++   L G +  +LPVP  NVINGG HAGN L  QEFMI+P+GA SFR+A+
Sbjct: 123 AAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAM 182

Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242
           R  +E YH LK VI +KYGK+A NVGDEGGFAP + E +E L+++ +AI++AGY   E++
Sbjct: 183 RLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYT--EKM 240

Query: 243 ALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEED 295
            + +D A+SEFY+DGKY +  K         T ++L  LY++    YP+VSIEDPF ++D
Sbjct: 241 VIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDD 300

Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355
           W  +   T  +G  +QIVGDDL VTNPKR+++ +E  A N LLLKVNQIG++TEA+ A  
Sbjct: 301 WAAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACK 358

Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415
           +A   G+GV+VSHRSGETED  IADL V L  GQIKTGAP RS+R AKYNQL+RIEEEL 
Sbjct: 359 LAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELG 418

Query: 416 GVAVYAGKNFR 426
             A +AG NFR
Sbjct: 419 DEARFAGHNFR 429


>dbj|BAA76924.1| (AB026051) enolase [Plasmodium falciparum]
           Length = 446
           
 Score =  464 bits (1182), Expect = e-130
 Identities = 249/440 (56%), Positives = 321/440 (72%), Gaps = 24/440 (5%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67
           I  + AREILDSRGNPTVEVD+ T + + RAAVPSGASTG +EA+ELRD  K RY GKGV
Sbjct: 5   ITRINAREILDSRGNPTVEVDLETNLGIFRAAVPSGASTGIYEALELRDNDKSRYLGKGV 64

Query: 68  RRAVENVNKIIAPELVGMDVRWQREIDRLLIE-LDGTEN-----KSNLGANAILAVSLAV 121
           ++A++N+N+IIAP+L+GM+   Q++ID L++E LDG++N     KS LGANAILA+S+AV
Sbjct: 65  QKAIKNINEIIAPKLIGMNCTEQKKIDNLMVEELDGSKNEWGWSKSKLGANAILAISMAV 124

Query: 122 AKAAANALELPLYQYLGGV-----NAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGAN 176
            +A A A ++ LY+YL  +     +  VLPVP  NVINGG HAGN L FQEFMI+P+GA 
Sbjct: 125 CRAGAAANKVSLYKYLAQLAGKKSDQMVLPVPCLNVINGGSHAGNKLSFQEFMIVPVGAP 184

Query: 177 SFREAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGY 236
           SF+EA+R+ +E YH LK  I +KYG +A NVGDEGGFAP +    E LD+L+ AI+ AGY
Sbjct: 185 SFKEALRYGAEVYHTLKSEIKKKYGIDATNVGDEGGFAPNILNANEALDLLVTAIKSAGY 244

Query: 237 KPGEEIALALDAASSEFYK--------DGKYIVSGKEY--TREELLELYKELTSTYPIVS 286
           +   ++ +A+D A+SEFY         D K   + K    T  +L++LY +L   YPIVS
Sbjct: 245 EG--KVKIAMDVAASEFYNSENKTYDLDFKTPNNDKSLVKTGAQLVDLYIDLVKKYPIVS 302

Query: 287 IEDPFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGT 346
           IEDPF ++DWE +  +T  +GK VQIVGDDL VTNP R+ K +E  A NAL LKVNQIG+
Sbjct: 303 IEDPFDQDDWENYAKLTAAIGKDVQIVGDDLLVTNPTRITKALEKNACNALPLKVNQIGS 362

Query: 347 LTEAMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQ 406
           +TEA++A  ++ +  +GV+VSHRSGETED  IADL VAL  GQIKTGAP RS+RNAKYNQ
Sbjct: 363 ITEAIEACLLSQKNNWGVMVSHRSGETEDVFIADLVVALRTGQIKTGAPCRSERNAKYNQ 422

Query: 407 LIRIEEELEGVAVYAGKNFR 426
           L+RIEE L   AV+AG+ FR
Sbjct: 423 LLRIEESLGNNAVFAGEKFR 442


>pir||JC1039 phosphopyruvate hydratase (EC 4.2.1.11) - rat
           Length = 434
           
 Score =  464 bits (1181), Expect = e-130
 Identities = 249/431 (57%), Positives = 314/431 (72%), Gaps = 17/431 (3%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67
           I  + AREILDSRGNPTVEVD+HT   + RAAVPSGASTG +EA+ELRDG K RY GKGV
Sbjct: 3   IQKIWAREILDSRGNPTVEVDLHTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGV 62

Query: 68  RRAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
            +AV+++N  IAP L+  G+ V  Q ++D L++ELDGTENKS  GANAIL VSLAV KA 
Sbjct: 63  LKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAG 122

Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182
           A    LPLY++   L G +  +LPVP  NVINGG HAGN L  QEFMI+P+GA SFR+A+
Sbjct: 123 AAEKNLPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAM 182

Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242
           R  +E YH LK VI +KYGK+A NVGDEGGFAP + E +E L+++ +AI++AGY   E++
Sbjct: 183 RLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYT--EKM 240

Query: 243 ALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEED 295
            + +D A+SEFY+DGKY +  K         T ++L  LY++    YP+VSIEDPF ++D
Sbjct: 241 VIGMDVAASEFYRDGKYDLDFKSPADPSRCITGDQLGALYQDFVRNYPVVSIEDPFDQDD 300

Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355
           W  +   T  +G  +QIVGDDL VTNPKR+++ +E  A N LLLKVNQIG++TEA+ A  
Sbjct: 301 WAAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACK 358

Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415
           +A   G+GV+VSHRSGETED  IADL V L  GQIKTGAP RS+R AKYNQL+RIEEE+ 
Sbjct: 359 LAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEEVG 418

Query: 416 GVAVYAGKNFR 426
             A +AG NFR
Sbjct: 419 EEARFAGHNFR 429


>pir||A53665 phosphopyruvate hydratase (EC 4.2.1.11) - liver fluke
           Length = 431
           
 Score =  464 bits (1180), Expect = e-129
 Identities = 250/432 (57%), Positives = 311/432 (71%), Gaps = 17/432 (3%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGKRYHGKGVR 68
           I A+ AR+I DSRGNPTVEVDV T   + RAAVPSGASTG HEA+ELRDG   Y GKGV 
Sbjct: 3   IKAIHARQIFDSRGNPTVEVDVTTAKGLFRAAVPSGASTGVHEALELRDGPPGYMGKGVL 62

Query: 69  RAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAA 126
           +AV NVN  IAP L+  G++V  Q  +D+ +++LDGT NK  LGANAIL VSLAV KA A
Sbjct: 63  KAVANVNSQIAPNLIKSGINVTDQAAVDKFMLDLDGTPNKEKLGANAILGVSLAVCKAGA 122

Query: 127 NALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIR 183
               LPLY+Y   L G    ++PVP  NVINGG HAGN L  QEFMIMP GA+SF EA++
Sbjct: 123 AEKGLPLYKYIATLAGNKEVIMPVPSFNVINGGSHAGNKLAMQEFMIMPTGASSFTEAMK 182

Query: 184 WVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIA 243
             SE YH L+ VI  KYG +A NVGDEGGFAP +++  E L++L  AI++AGY    ++ 
Sbjct: 183 IGSEVYHNLRAVIKSKYGLDACNVGDEGGFAPSIQDNLEGLELLRTAIDKAGYTG--KVK 240

Query: 244 LALDAASSEFYKDGKYIVSGKE--------YTREELLELYKELTSTYPIVSIEDPFHEED 295
           +A+D A+SEFYK+GKY +  K          T + + ++YK++ STYPIVSIEDPF ++D
Sbjct: 241 IAMDCAASEFYKEGKYDLDFKNPKSQASSWITSDAMADVYKKMMSTYPIVSIEDPFDQDD 300

Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355
           W  +  +T E   K+QIVGDDL VTNP R++K I+  A N LLLKVNQIG+++E++ A  
Sbjct: 301 WPAWTKLTGEC--KIQIVGDDLTVTNPLRVQKAIDQKACNCLLLKVNQIGSVSESIKACK 358

Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415
           MA  AG+GV+VSHRSGETED  IADL V L  GQIKTGAP RS+R AKYNQL+RIEE+L 
Sbjct: 359 MAQEAGWGVMVSHRSGETEDNFIADLVVGLRTGQIKTGAPCRSERLAKYNQLLRIEEDLG 418

Query: 416 GVAVYAGKNFRK 427
           G A YAG+NFR+
Sbjct: 419 GAAKYAGENFRR 430


>gi|7305027 enolase 2, gamma neuronal [Mus musculus]
           >gi|119348|sp|P17183|ENOG_MOUSE GAMMA ENOLASE
           (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (NEURAL ENOLASE)
           (NSE) >gi|109805|pir||S10247 phosphopyruvate hydratase
           (EC 4.2.1.11) gamma - mouse >gi|55495|emb|CAA36606.1|
           (X52380) gamma-enolase (AA 1-434) [Mus sp.]
           >gi|2289903|gb|AAC36002.1| (AC002397) ENO2 [Mus
           musculus]
           Length = 434
           
 Score =  463 bits (1178), Expect = e-129
 Identities = 249/431 (57%), Positives = 315/431 (72%), Gaps = 17/431 (3%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67
           I  + AREILDSRGNPTVEVD++T   + RAAVPSGASTG +EA+ELRDG K RY GKGV
Sbjct: 3   IEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGV 62

Query: 68  RRAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
            +AV+++N  IAP L+  G+ V  Q ++D L++ELDGTENKS  GANAIL VSLAV KA 
Sbjct: 63  LKAVDHINSRIAPALISSGISVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAG 122

Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182
           A   +LPLY++   L G +  +LPVP  NVINGG HAGN L  QEFMI+P+GA SFR+A+
Sbjct: 123 AAERDLPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAM 182

Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242
           R  +E YH LK VI +KYGK+A NVGDEGGFAP + E +E L+++ +AI++AGY   E++
Sbjct: 183 RLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYT--EKM 240

Query: 243 ALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEED 295
            + +D A+SEFY+DGKY +  K         T ++L  LY++    YP+VSIEDPF ++D
Sbjct: 241 VIGMDVAASEFYRDGKYDLDFKSPADPSRYITGDQLGALYQDFVRNYPVVSIEDPFDQDD 300

Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355
           W  +   T  +G  +QIVGDDL VTNPKR+++ +E  A N LLLKVNQIG++TEA+ A  
Sbjct: 301 WAAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACK 358

Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415
           +A   G+GV+VSHRSGETED  IADL V L  GQIKTGAP RS+R AKYNQL+RIEEEL 
Sbjct: 359 LAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELG 418

Query: 416 GVAVYAGKNFR 426
             A +AG NFR
Sbjct: 419 DEARFAGHNFR 429


>emb|CAC00532.1| (AJ132580) enolase, isoform 1 [Hevea brasiliensis]
           Length = 445
           
 Score =  463 bits (1178), Expect = e-129
 Identities = 257/438 (58%), Positives = 314/438 (71%), Gaps = 21/438 (4%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPIS-MGRAAVPSGASTGTHEAVELRDGGKRYHGKGV 67
           IV+V AR+I DSRGNPTVE DV      + RAAVPSGASTG +EA+ELRDGG  Y GKGV
Sbjct: 5   IVSVRARQIFDSRGNPTVEADVKLSDGYLARAAVPSGASTGIYEALELRDGGSDYLGKGV 64

Query: 68  RRAVENVNKIIAPELVGMDVRWQREIDRLLIE-LDGTEN-----KSNLGANAILAVSLAV 121
            +AVENVN II P LVG D   Q  ID  +++ LDGT N     K  LGANAILAVSLAV
Sbjct: 65  SKAVENVNIIIGPALVGKDPTDQVGIDNFMVQQLDGTVNEWGWCKQKLGANAILAVSLAV 124

Query: 122 AKAAANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSF 178
            KA A+   +PLY++   L G    VLPVP  NVINGG HAGN L  QEFMI+P+GA+SF
Sbjct: 125 CKAGAHVKGIPLYEHIANLAGNKNLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSF 184

Query: 179 REAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKP 238
           +EA++  +E YH LK VI +KYG++A NVGDEGGFAP ++E  E L++L  AI +AGY  
Sbjct: 185 KEAMKMGAEVYHHLKSVIKKKYGQDATNVGDEGGFAPNIQENKEGLELLKTAIAKAGYTG 244

Query: 239 GEEIALALDAASSEFY-KDGKYIVSGKEYTR--------EELLELYKELTSTYPIVSIED 289
             ++ + +D A+SEFY  D  Y ++ KE           E L +LYK   + YPIVSIED
Sbjct: 245 --KVVIGMDVAASEFYGSDQTYDLNFKEENNNGSQKISGEALKDLYKSFVAEYPIVSIED 302

Query: 290 PFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTE 349
           PF ++DW  +  +T E+G+KVQIVGDDL VTNPKR++K I+  A NALLLKVNQIG++TE
Sbjct: 303 PFDQDDWAHYAKLTSEIGEKVQIVGDDLLVTNPKRVEKAIKEKACNALLLKVNQIGSVTE 362

Query: 350 AMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIR 409
           +++A  M+ RAG+GV+ SHRSGETED  IADL+V L  GQIKTGAP RS+R AKYNQL+R
Sbjct: 363 SIEAVKMSKRAGWGVMASHRSGETEDTFIADLSVGLATGQIKTGAPCRSERLAKYNQLLR 422

Query: 410 IEEELEGVAVYAGKNFRK 427
           IEEEL   AVYAG NFRK
Sbjct: 423 IEEELGSEAVYAGANFRK 440


>sp|P42896|ENO_RICCO ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|542019|pir||S39203 phosphopyruvate
           hydratase (EC 4.2.1.11) - castor bean
           >gi|433609|emb|CAA82232.1| (Z28386) enolase [Ricinus
           communis]
           Length = 445
           
 Score =  462 bits (1177), Expect = e-129
 Identities = 254/437 (58%), Positives = 313/437 (71%), Gaps = 21/437 (4%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPIS-MGRAAVPSGASTGTHEAVELRDGGKRYHGKGV 67
           IV+V AR+I DSRGNPTVE D+      + RAAVPSGASTG +EA+ELRDGG  Y GKGV
Sbjct: 5   IVSVRARQIFDSRGNPTVEADIKLSDGHLARAAVPSGASTGIYEALELRDGGSDYLGKGV 64

Query: 68  RRAVENVNKIIAPELVGMDVRWQREIDRLLI-ELDGTEN-----KSNLGANAILAVSLAV 121
            +AVENVN II P L+G D   Q  +D  ++ ELDGT N     K  LGANAILAVSLA+
Sbjct: 65  SKAVENVNSIIGPALIGKDPTEQTALDNFMVQELDGTVNEWGWCKQKLGANAILAVSLAL 124

Query: 122 AKAAANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSF 178
            KA A+   +PLY++   L G    VLPVP  NVINGG HAGN L  QEFMI+P+GA+SF
Sbjct: 125 CKAGAHVKGIPLYKHIANLAGNKNLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSF 184

Query: 179 REAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKP 238
           +EA++  +E YH LK VI +KYG++A NVGDEGGFAP ++E  E L++L  AI +AGY  
Sbjct: 185 KEAMKMGAEVYHHLKSVIKKKYGQDATNVGDEGGFAPNIQENKEGLELLKTAIAKAGYTG 244

Query: 239 GEEIALALDAASSEFY-KDGKYIVSGKEYTR--------EELLELYKELTSTYPIVSIED 289
             ++ + +D A+SEFY  D  Y ++ KE           E L +LYK   S YPIVSIED
Sbjct: 245 --KVVIGMDVAASEFYGSDKTYDLNFKEENNDGSQKISGEALKDLYKSFASEYPIVSIED 302

Query: 290 PFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTE 349
           PF ++DWE +  +T E+G+KVQIVGDDL VTNPKR++K I+  A NALLLKVNQIG++TE
Sbjct: 303 PFDQDDWEHYSKLTSEIGEKVQIVGDDLLVTNPKRVEKAIQEKACNALLLKVNQIGSVTE 362

Query: 350 AMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIR 409
           +++A  M+ RAG+GV+ SHRSGETED  IADL+V L  GQIKTGAP RS+R AKYNQL+R
Sbjct: 363 SIEAVRMSKRAGWGVMASHRSGETEDTFIADLSVGLATGQIKTGAPCRSERLAKYNQLLR 422

Query: 410 IEEELEGVAVYAGKNFR 426
           IEEEL   AVYAG  FR
Sbjct: 423 IEEELGAEAVYAGAKFR 439


>sp|O57391|ENOG_CHICK GAMMA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (NEURAL ENOLASE)
           (NSE) >gi|2842531|dbj|BAA24680.1| (AB004291)
           gamma-subunit of enolase [Gallus gallus]
           Length = 434
           
 Score =  462 bits (1177), Expect = e-129
 Identities = 248/426 (58%), Positives = 314/426 (73%), Gaps = 17/426 (3%)

Query: 14  AREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRAVE 72
           AREILDSRGNPTVEVD++T   M RAAVPSGASTG +EA+ELRD  K R+ GKGV +AV+
Sbjct: 8   AREILDSRGNPTVEVDLYTHKGMFRAAVPSGASTGIYEALELRDNDKSRFLGKGVLQAVD 67

Query: 73  NVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANALE 130
           ++N  +AP +VG  + V  Q +ID L++E+DGTENKS  GANAIL VSLAV KA A   +
Sbjct: 68  HINSTVAPAIVGSGLSVVDQEKIDNLMLEMDGTENKSKFGANAILGVSLAVCKAGAAEKD 127

Query: 131 LPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVSE 187
           +PLY++   L G +  +LPVP  NVINGG HAGN L  QEFMI+P+GA SFR+A+R  +E
Sbjct: 128 VPLYRHIADLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMRIGAE 187

Query: 188 TYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALALD 247
            YH LK VI EKYGK+A NVGDEGGFAP + E +E L++L +AI++AGY   ++I + +D
Sbjct: 188 VYHNLKSVIKEKYGKDATNVGDEGGFAPNILENSEALELLKEAIDKAGYT--DKIVIGMD 245

Query: 248 AASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEEDWEGFV 300
            A+SEFY+DGKY +  K         + +EL +LY+     YP++SIEDPF ++DWE + 
Sbjct: 246 VAASEFYRDGKYDLDFKSPDDPSRYISADELGDLYQSFVRAYPVLSIEDPFDQDDWEAWS 305

Query: 301 MITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRA 360
             T  +G  +QIVGDDL VTNPKR+++ +E  A N LLLKVNQIG++TEA+ A  +A   
Sbjct: 306 KFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQEN 363

Query: 361 GYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVY 420
           G+GV+VSHRSGETED  IADL VAL  GQIKTGAP RS+R AKYNQL+RIEEEL   A +
Sbjct: 364 GWGVMVSHRSGETEDTFIADLVVALCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARF 423

Query: 421 AGKNFR 426
           AG NFR
Sbjct: 424 AGHNFR 429


>sp|O85348|ENO_NITEU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|3493583|gb|AAC33442.1| (AF061753)
           enolase; 2-phospho-D-glycerate hydrolase [Nitrosomonas
           europaea]
           Length = 428
           
 Score =  462 bits (1177), Expect = e-129
 Identities = 243/420 (57%), Positives = 312/420 (73%), Gaps = 6/420 (1%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPIS-MGRAAVPSGASTGTHEAVELRDG-GKRYHGKG 66
           IV VIAREI+DSRGNPT+E DV      +GRA+VPSGAS GT EAVELRDG  +RY+GKG
Sbjct: 4   IVDVIAREIIDSRGNPTIEADVLLESGVLGRASVPSGASVGTREAVELRDGDAQRYYGKG 63

Query: 67  VRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAA 126
           V +AVE+VN  I+  ++G+D   Q  ID+ LIELDG+ENKS LGANAILAVSLAVAKAAA
Sbjct: 64  VLKAVESVNGEISETIMGLDAMEQCFIDKTLIELDGSENKSRLGANAILAVSLAVAKAAA 123

Query: 127 NALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVS 186
               LPLY+YLGG+NA  LPVP+ N++NGGVHA N LD QEFMI+P+G  + REA+R  +
Sbjct: 124 EESGLPLYRYLGGINAKWLPVPMMNLVNGGVHANNRLDMQEFMIIPLGLPNLREAVRCGA 183

Query: 187 ETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALAL 246
           E +  L+ ++ ++       VGDEGGFAP      E L ++++AI+EAGY+PG E+A+ +
Sbjct: 184 EVFSTLRTLLNKR--NLPTTVGDEGGFAPSFARNEEALALIVQAIDEAGYQPGSEVAIGV 241

Query: 247 DAASSEFYKDGKYI--VSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMITR 304
           D ASSEF+++GKY   V G   T  + ++        YPI+SIED   E+DWEG+ ++T 
Sbjct: 242 DCASSEFFREGKYHLDVDGLGLTSAQFVDYLATWVEKYPIISIEDGMSEQDWEGWGLLTE 301

Query: 305 ELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYGV 364
            LGK VQ+VGDD+FVTN + LK+GI    AN++L+K+NQIGTLTE ++A  MA  AGY  
Sbjct: 302 RLGKTVQLVGDDVFVTNTRILKEGISRNIANSILIKINQIGTLTETLNAIEMAKCAGYTA 361

Query: 365 VVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAGKN 424
           +VSHRSGETED TIAD+AVA NA QIKTG+ +RSDR AKYNQL+RIEE+L  +A YAG++
Sbjct: 362 IVSHRSGETEDTTIADIAVATNALQIKTGSLSRSDRLAKYNQLLRIEEDLGEMAQYAGRS 421


>sp|Q27655|ENO_FASHE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|499267|gb|AAA57450.1| (U10297) enolase
           [Fasciola hepatica]
           Length = 431
           
 Score =  462 bits (1176), Expect = e-129
 Identities = 249/432 (57%), Positives = 310/432 (71%), Gaps = 17/432 (3%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGKRYHGKGVR 68
           I A+ AR+I DSRGNPTVEVDV T   + RAAVPSGASTG HEA+ELRDG   Y GKGV 
Sbjct: 3   IKAIHARQIFDSRGNPTVEVDVTTAKGLFRAAVPSGASTGVHEALELRDGPPGYMGKGVL 62

Query: 69  RAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAA 126
           +AV NVN  IAP L+  G++V  Q  +D+ +++LDGT NK  LGANAIL VSLA  KA A
Sbjct: 63  KAVANVNSQIAPNLIKSGINVTDQAAVDKFMLDLDGTPNKEKLGANAILGVSLAXCKAGA 122

Query: 127 NALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIR 183
               LPLY+Y   L G    ++PVP  NVINGG HAGN L  QEFMIMP GA+SF EA++
Sbjct: 123 AEKGLPLYKYIATLAGNKEVIMPVPSFNVINGGSHAGNKLAMQEFMIMPTGASSFTEAMK 182

Query: 184 WVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIA 243
             SE YH L+ VI  KYG +A NVGDEGGFAP +++  E L++L  AI++AGY    ++ 
Sbjct: 183 IGSEVYHNLRAVIKSKYGLDACNVGDEGGFAPSIQDNLEGLELLRTAIDKAGYTG--KVX 240

Query: 244 LALDAASSEFYKDGKYIVSGKE--------YTREELLELYKELTSTYPIVSIEDPFHEED 295
           +A+D A+SEFYK+GKY +  K          T + + ++YK++ STYPIVSIEDPF ++D
Sbjct: 241 IAMDCAASEFYKEGKYDLDFKNPKSQASSWITSDAMADVYKKMMSTYPIVSIEDPFDQDD 300

Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355
           W  +  +T E   K+QIVGDDL VTNP R++K I+  A N LLLKVNQIG+++E++ A  
Sbjct: 301 WPAWTKLTGEC--KIQIVGDDLTVTNPLRVQKAIDQKACNCLLLKVNQIGSVSESIKACK 358

Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415
           MA  AG+GV+VSHRSGETED  IADL V L  GQIKTGAP RS+R AKYNQL+RIEE+L 
Sbjct: 359 MAQEAGWGVMVSHRSGETEDNFIADLVVGLRTGQIKTGAPCRSERLAKYNQLLRIEEDLG 418

Query: 416 GVAVYAGKNFRK 427
           G A YAG+NFR+
Sbjct: 419 GAAKYAGENFRR 430


>pir||A72477 probable enolase APE2458 - Aeropyrum pernix (strain K1)
           >gi|5106162|dbj|BAA81473.1| (AP000064) 432aa long
           hypothetical enolase [Aeropyrum pernix]
           Length = 432
           
 Score =  462 bits (1175), Expect = e-129
 Identities = 241/425 (56%), Positives = 297/425 (69%), Gaps = 1/425 (0%)

Query: 5   NPYEIVAVIAREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRDGGKRYH 63
           N + I  V   ++LDSRGNPTV+  V     S+G    PSGAS G  EAVELRDGG ++ 
Sbjct: 4   NDFAIERVWGLQVLDSRGNPTVKAYVKLAGGSLGWGIAPSGASRGEREAVELRDGGGKWR 63

Query: 64  GKGVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAK 123
           GKGV RAV  +N ++AP L G+D R Q +IDRLLIELDGT NKS LG N   A+S+AV++
Sbjct: 64  GKGVSRAVSLLNTVVAPRLEGVDARRQAQIDRLLIELDGTPNKSRLGGNTTTALSIAVSR 123

Query: 124 AAANALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIR 183
           AAA    L L+QYLGG  A  LP+PL NVINGGVHAGN+LDFQEFMI+P G  SF EA+R
Sbjct: 124 AAAAQARLELFQYLGGAGARRLPIPLLNVINGGVHAGNELDFQEFMIIPYGFESFTEAMR 183

Query: 184 WVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIA 243
              ETY  LK ++ ++YG +AVNVGDEGGFAPPM+   E L  L+ A+E+AGY+PG EIA
Sbjct: 184 AAVETYGELKSLLKDRYGASAVNVGDEGGFAPPMRSAEEALKTLVDAVEKAGYQPGSEIA 243

Query: 244 LALDAASSEFYKDGKYIVSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMIT 303
           L +DAA+S+ Y +G+Y V GK  +REELL LY+ L   YPIV +EDPF E+D+EGF    
Sbjct: 244 LGIDAAASQLYSNGRYSVEGKSLSREELLSLYQRLVEQYPIVYLEDPFSEDDYEGFKAAV 303

Query: 304 RELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYG 363
             L  +  IVGDDL VTNP+R+K+   + A   LL+KVNQ+GTLTEA++A   A   G  
Sbjct: 304 DALSTETIIVGDDLLVTNPQRVKEASALKAVTGLLVKVNQVGTLTEALEAIQAARDRGIV 363

Query: 364 VVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAGK 423
            +VSHRSG+TED  IADLAVA  A  IKTGAPAR +R +KYN+L+ IE  L   A YAG 
Sbjct: 364 HIVSHRSGDTEDTFIADLAVATEALMIKTGAPARGERTSKYNRLLEIENILGYSAEYAGP 423

Query: 424 NFRKV 428
             R V
Sbjct: 424 ELRGV 428


>sp|P25696|ENO_ARATH ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|81608|pir||JQ1187 phosphopyruvate
           hydratase (EC 4.2.1.11) - Arabidopsis thaliana
           >gi|16271|emb|CAA41114.1| (X58107) enolase [Arabidopsis
           thaliana] >gi|4581151|gb|AAD24635.1|AC006919_15
           (AC006919) enolase (2-phospho-D-glycerate hydroylase)
           [Arabidopsis thaliana]
           Length = 444
           
 Score =  461 bits (1173), Expect = e-129
 Identities = 254/438 (57%), Positives = 311/438 (70%), Gaps = 21/438 (4%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMG-RAAVPSGASTGTHEAVELRDGGKRYHGKGV 67
           I  V AR+I DSRGNPTVEVD+HT   +   AAVPSGASTG +EA+ELRDGG  Y GKGV
Sbjct: 4   ITVVKARQIFDSRGNPTVEVDIHTSNGIKVTAAVPSGASTGIYEALELRDGGSDYLGKGV 63

Query: 68  RRAVENVNKIIAPELVGMDVRWQREIDRLLI-ELDGTEN-----KSNLGANAILAVSLAV 121
            +AV NVN II P L+G D   Q  ID  ++ ELDGT+N     K  LGANAILAVSLAV
Sbjct: 64  SKAVGNVNNIIGPALIGKDPTQQTAIDNFMVHELDGTQNEWGWCKQKLGANAILAVSLAV 123

Query: 122 AKAAANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSF 178
            KA A    +PLY++   L G    VLPVP  NVINGG HAGN L  QEFMI+P+GA SF
Sbjct: 124 CKAGAVVSGIPLYKHIANLAGNPKIVLPVPAFNVINGGSHAGNKLAMQEFMILPVGAASF 183

Query: 179 REAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKP 238
           +EA++   E YH LK VI +KYG++A NVGDEGGFAP ++E  E L++L  AIE+AGY  
Sbjct: 184 KEAMKMGVEVYHHLKSVIKKKYGQDATNVGDEGGFAPNIQENKEGLELLKTAIEKAGYTG 243

Query: 239 GEEIALALDAASSEFYKDGK-YIVSGKEYTR--------EELLELYKELTSTYPIVSIED 289
             ++ + +D A+SEFY + K Y ++ KE           + L +LYK   + YPIVSIED
Sbjct: 244 --KVVIGMDVAASEFYSEDKTYDLNFKEENNNGSQKISGDALKDLYKSFVAEYPIVSIED 301

Query: 290 PFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTE 349
           PF ++DWE +  +T E G +VQIVGDDL VTNPKR+ K I   + NALLLKVNQIG++TE
Sbjct: 302 PFDQDDWEHYAKMTTECGTEVQIVGDDLLVTNPKRVAKAIAEKSCNALLLKVNQIGSVTE 361

Query: 350 AMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIR 409
           +++A  M+ +AG+GV+ SHRSGETED  IADLAV L+ GQIKTGAP RS+R AKYNQL+R
Sbjct: 362 SIEAVKMSKKAGWGVMTSHRSGETEDTFIADLAVGLSTGQIKTGAPCRSERLAKYNQLLR 421

Query: 410 IEEELEGVAVYAGKNFRK 427
           IEEEL   A+YAG NFRK
Sbjct: 422 IEEELGSEAIYAGVNFRK 439


>sp|Q42971|ENO_ORYSA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) (OSE1) >gi|7436887|pir||T03267 probable
           phosphopyruvate hydratase (EC 4.2.1.11) - rice
           >gi|780372|gb|AAC49173.1| (U09450) enolase [Oryza
           sativa]
           Length = 446
           
 Score =  460 bits (1172), Expect = e-128
 Identities = 253/438 (57%), Positives = 314/438 (70%), Gaps = 22/438 (5%)

Query: 9   IVAVIAREILDSRGNPTVEVDVH-TPISMGRAAVPSGASTGTHEAVELRDGGKRYHGKGV 67
           IV+V AR+I DSRGNPTVEVDV  +  +  RAAVPSGASTG +EA+ELRDGG  Y GKGV
Sbjct: 5   IVSVKARQIFDSRGNPTVEVDVCCSDGTFARAAVPSGASTGVYEALELRDGGSDYLGKGV 64

Query: 68  RRAVENVNKIIAPELVGMDVRWQREIDRLLIE-LDGTEN-----KSNLGANAILAVSLAV 121
            +AV+NVN +IAP L+G D   Q E+D  +++ LDGT+N     K  LGANAILAVSLA+
Sbjct: 65  SKAVDNVNSVIAPALIGKDPTSQAELDNFMVQQLDGTKNEWGWCKQKLGANAILAVSLAI 124

Query: 122 AKAAANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSF 178
            KA A   ++PLYQ+   L G    VLPVP  NVINGG HAGN L  QEFMI+P GA SF
Sbjct: 125 CKAGAIIKKIPLYQHIANLAGNKQLVLPVPAFNVINGGSHAGNKLAMQEFMILPTGAASF 184

Query: 179 REAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKP 238
           +EA++   E YH LK VI +KYG++A NVGDEGGFAP ++E  E L++L  AIE+AGY  
Sbjct: 185 KEAMKMGVEVYHNLKSVIKKKYGQDATNVGDEGGFAPNIQENKEGLELLKTAIEKAGYTG 244

Query: 239 GEEIALALDAASSEFY--KDGKYIVSGKEYTRE--------ELLELYKELTSTYPIVSIE 288
             ++ + +D A+SEFY  KD  Y ++ KE   +         L  +YK   S YPIVSIE
Sbjct: 245 --KVVIGMDVAASEFYNDKDKTYDLNFKEENNDGSQKISGDSLKNVYKSFVSEYPIVSIE 302

Query: 289 DPFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLT 348
           DPF ++DWE +  +T E+G++VQIVGDDL VTNP R+ K I+  + NALLLKVNQIG++T
Sbjct: 303 DPFDQDDWEHYAKMTAEIGEQVQIVGDDLLVTNPTRVAKAIQEKSCNALLLKVNQIGSVT 362

Query: 349 EAMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLI 408
           E+++A  M+ RAG+GV+ SHRSGETED  IA+LAV L  GQIKTGAP RS+R AKYNQL+
Sbjct: 363 ESIEAVKMSKRAGWGVMTSHRSGETEDTFIAELAVGLATGQIKTGAPCRSERLAKYNQLL 422

Query: 409 RIEEELEGVAVYAGKNFR 426
           RIEEEL   AVYAG  FR
Sbjct: 423 RIEEELGAAAVYAGAKFR 440


>gb|AAD41646.1|AF072589_1 (AF072589) alpha enolase [Python regius]
           Length = 434
           
 Score =  460 bits (1172), Expect = e-128
 Identities = 248/431 (57%), Positives = 310/431 (71%), Gaps = 17/431 (3%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67
           I+ + AREI DSRGNPT+EVD++T   + RAAVPSGASTG +EA+ELRD  K R+ GKGV
Sbjct: 3   ILKIQAREIFDSRGNPTIEVDLYTKKGLFRAAVPSGASTGIYEALELRDNDKTRFLGKGV 62

Query: 68  RRAVENVNKIIAPELVGMDVRW--QREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
            +AVE+VNK IAP LV  +V    Q +ID+L+IE+DG+ENKS  GANAIL VSLAV KA 
Sbjct: 63  SKAVEHVNKTIAPALVNKNVSVVEQEKIDKLMIEMDGSENKSKFGANAILGVSLAVCKAG 122

Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182
           A   ++PLY++   L G    +LPVP  NVINGG HAGN L  QEFMI+PIGA  F+EA+
Sbjct: 123 AAEKDIPLYRHIADLAGNKEVILPVPAFNVINGGSHAGNKLAMQEFMILPIGAECFKEAM 182

Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242
           R  +E YH LK VI EKYGK+A NVGDEGGFAP + E  E L++L  AI +AGY   ++I
Sbjct: 183 RIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKTAISKAGY--ADKI 240

Query: 243 ALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEED 295
            + +D A+SEFY+DGKY +  K         T ++L +LYK     YP+VSIEDPF ++D
Sbjct: 241 VIGMDVAASEFYRDGKYDLDFKSPDDRSRYITPDQLADLYKGFVKNYPVVSIEDPFDQDD 300

Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355
           W  +   T E G  +Q+VGDDL VTNPKR+ K ++  + N LLLKVNQIG++TE++ A  
Sbjct: 301 WPAWKKFTAESG--IQVVGDDLTVTNPKRIAKAVQEKSCNCLLLKVNQIGSVTESLQACK 358

Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415
           +A   G+GV+VSHRSGETED  IADL V L  GQIKTGAP RS+R AKYNQL+RIEEEL 
Sbjct: 359 LAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELG 418

Query: 416 GVAVYAGKNFR 426
             A +AG+NFR
Sbjct: 419 SKARFAGRNFR 429


>sp|P42895|ENO2_MAIZE ENOLASE 2 (2-PHOSPHOGLYCERATE DEHYDRATASE 2) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE 2) >gi|7436888|pir||T02221 phosphopyruvate
           hydratase (EC 4.2.1.11) - maize
           >gi|602253|gb|AAD04187.1| (U17973) enolase [Zea mays]
           Length = 446
           
 Score =  460 bits (1171), Expect = e-128
 Identities = 253/438 (57%), Positives = 312/438 (70%), Gaps = 22/438 (5%)

Query: 9   IVAVIAREILDSRGNPTVEVDVH-TPISMGRAAVPSGASTGTHEAVELRDGGKRYHGKGV 67
           I +V AR+I DSRGNPTVEVDV  +  +  RAAVPSGASTG +EA+ELRDGG  Y GKGV
Sbjct: 5   IQSVKARQIFDSRGNPTVEVDVFCSDGTFARAAVPSGASTGVYEALELRDGGSYYLGKGV 64

Query: 68  RRAVENVNKIIAPELVGMDVRWQREIDRLLIE-LDGTEN-----KSNLGANAILAVSLAV 121
            +AV NVN +I P L+G D   Q EID  +++ LDGT+N     K  LGANAILAVSLAV
Sbjct: 65  SKAVNNVNSVIGPALIGKDPTAQTEIDNFMVQQLDGTKNEWGWCKQKLGANAILAVSLAV 124

Query: 122 AKAAANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSF 178
            KA A+   +PLYQ+   L G    VLPVP  NVINGG HAGN L  QEFMI+P GA SF
Sbjct: 125 CKAGASIKRIPLYQHIANLAGNKQLVLPVPAFNVINGGSHAGNKLAMQEFMILPTGAASF 184

Query: 179 REAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKP 238
           +EA++   E YH LK VI +KYG++A NVGDEGGFAP ++E  E L++L  AIE+AGY  
Sbjct: 185 KEAMKMGVEVYHHLKSVIKKKYGQDATNVGDEGGFAPNIQENKEGLELLKTAIEKAGYTG 244

Query: 239 GEEIALALDAASSEFY--KDGKYIVSGKEYTRE--------ELLELYKELTSTYPIVSIE 288
             ++ + +D A+SEFY  KD  Y ++ KE   +         L  +YK   S YPIVSIE
Sbjct: 245 --KVVIGMDVAASEFYSDKDQTYDLNFKEENNDGSQKISGDSLKNVYKSFVSEYPIVSIE 302

Query: 289 DPFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLT 348
           DPF ++DW  +  +T E+G++VQIVGDDL VTNP R+ K I+  + NALLLKVNQIG++T
Sbjct: 303 DPFDQDDWVHYAKMTEEIGEQVQIVGDDLLVTNPTRVAKAIKEKSCNALLLKVNQIGSVT 362

Query: 349 EAMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLI 408
           E+++A  M+ RAG+GV+ SHRSGETED  IADLAV L+ GQIKTGAP RS+R AKYNQL+
Sbjct: 363 ESIEAVKMSKRAGWGVMTSHRSGETEDTFIADLAVGLSTGQIKTGAPCRSERLAKYNQLL 422

Query: 409 RIEEELEGVAVYAGKNFR 426
           RIEEEL  +AVYAG  FR
Sbjct: 423 RIEEELGAIAVYAGAKFR 440


>sp|P08324|ENO_ECOLI ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|7428364|pir||NOEC phosphopyruvate
           hydratase (EC 4.2.1.11) - Escherichia coli  (strain
           K-12) >gi|882673|gb|AAA69289.1| (U29580) enolase
           [Escherichia coli] >gi|1789141|gb|AAC75821.1| (AE000361)
           enolase [Escherichia coli K12]
           Length = 432
           
 Score =  460 bits (1171), Expect = e-128
 Identities = 249/425 (58%), Positives = 309/425 (72%), Gaps = 11/425 (2%)

Query: 8   EIVAVIAREILDSRGNPTVEVDVHTPIS-MGRAAVPSGASTGTHEAVELRDGGK-RYHGK 65
           +IV +I REI+DSRGNPTVE +VH     +G AA PSGASTG+ EA+ELRDG K R+ GK
Sbjct: 3   KIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGK 62

Query: 66  GVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
           GV +AV  VN  IA  L+G D + Q  ID+++I+LDGTENKS  GANAILAVSLA AKAA
Sbjct: 63  GVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAA 122

Query: 126 ANALELPLYQYLGGVNA----YVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREA 181
           A A  +PLY+++  +N     Y +PVP+ N+INGG HA N++D QEFMI P+GA + +EA
Sbjct: 123 AAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEA 182

Query: 182 IRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEE 241
           IR  SE +H L KV+  K G N   VGDEGG+AP +    E L V+ +A++ AGY+ G++
Sbjct: 183 IRMGSEVFHHLAKVLKAK-GMNTA-VGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKD 240

Query: 242 IALALDAASSEFYKDGKYIVSG---KEYTREELLELYKELTSTYPIVSIEDPFHEEDWEG 298
           I LA+D A+SEFYKDGKY+++G   K +T EE     +ELT  YPIVSIED   E DW+G
Sbjct: 241 ITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDG 300

Query: 299 FVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAF 358
           F   T+ LG K+Q+VGDDLFVTN K LK+GIE G AN++L+K NQIG+LTE + A  MA 
Sbjct: 301 FAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAK 360

Query: 359 RAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVA 418
            AGY  V+SHRSGETEDATIADLAV   AGQIKTG+ +RSDR AKYNQLIRIEE L   A
Sbjct: 361 DAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKA 420

Query: 419 VYAGK 423
            Y G+
Sbjct: 421 PYNGR 425


>sp|P33675|ENO_ZYMMO ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|538726|pir||A45732 phosphopyruvate
           hydratase (EC 4.2.1.11) - Zymomonas mobilis
           >gi|155581|gb|AAA27686.1| (M99380) enolase [Zymomonas
           mobilis]
           Length = 428
           
 Score =  459 bits (1169), Expect = e-128
 Identities = 248/422 (58%), Positives = 310/422 (72%), Gaps = 9/422 (2%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRDGGK-RYHGKG 66
           IV++  R+++DSRGNPTVEVDV     S GRAAVPSGASTG HEAVELRDG K R+ GKG
Sbjct: 4   IVSIHGRQVVDSRGNPTVEVDVTLEDGSFGRAAVPSGASTGVHEAVELRDGDKTRWGGKG 63

Query: 67  VRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAA 126
           V +AV  VN  IA  ++G++   Q  ID+ +I+LDGT NK   GANAIL VSLAVAKAAA
Sbjct: 64  VTKAVHAVNNEIANAIIGLEAEDQELIDQTMIKLDGTPNKGKFGANAILGVSLAVAKAAA 123

Query: 127 NALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVS 186
            A  LPLY+Y+GG  A+VLPVP+ N++NGG+HA N +DFQEFMI P+GA+S  EA+R  +
Sbjct: 124 EARGLPLYRYVGGTAAHVLPVPMMNIVNGGMHADNPIDFQEFMIAPVGASSINEAVRIGT 183

Query: 187 ETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALAL 246
           E +H LKK ++ K G N  NVGDEGGFAP +   +  LD ++ +I +AGYKPGE++ +AL
Sbjct: 184 EVFHTLKKELSAK-GMN-TNVGDEGGFAPSLDSASSALDFIVDSISKAGYKPGEDVFIAL 241

Query: 247 DAASSEFYKDGKYIV----SGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMI 302
           DAASSEFY   + I      G++ T  +L++ Y EL   YPI SIED   E+D+E + ++
Sbjct: 242 DAASSEFYNKDQNIYDLKGEGRKLTSAQLVDYYVELCGKYPIYSIED-LAEDDFEFWKIL 300

Query: 303 TRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGY 362
           T +LG KVQ+VGDDLFVTN KRL  GIE G AN+LL+K NQIG+L+E + A  MA  A Y
Sbjct: 301 TEKLGDKVQLVGDDLFVTNVKRLSDGIERGIANSLLVKFNQIGSLSETLAAVNMANDASY 360

Query: 363 GVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAG 422
             V+SHRS ETED TIADLAVA N GQIKTG+  RS+R AKYNQL+RIEEEL  VA YAG
Sbjct: 361 TPVMSHRSVETEDTTIADLAVATNCGQIKTGSLCRSERIAKYNQLMRIEEELGSVAKYAG 420

Query: 423 KN 424
           ++
Sbjct: 421 RS 422


>dbj|BAA81815.1| (AB029313) enolase [Streptococcus intermedius]
           Length = 434
           
 Score =  459 bits (1169), Expect = e-128
 Identities = 240/424 (56%), Positives = 303/424 (70%), Gaps = 12/424 (2%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRDGGK-RYHGKG 66
           I  V ARE+LDSRGNPT+EV+V+T   + GR  VPSGASTG HEAVELRDG K RY G G
Sbjct: 4   ITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKSRYGGLG 63

Query: 67  VRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAA 126
            ++AV+NVN IIA  ++G DVR Q+ IDR +I LDGT NK  LGANAIL VS+AVA+AAA
Sbjct: 64  TQKAVDNVNNIIAEAVIGYDVRDQQAIDRAMIALDGTPNKGKLGANAILGVSIAVARAAA 123

Query: 127 NALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVS 186
           + LE+PLY YLGG N  VLP P+ N+INGG H+   + FQEFMI+P GA +F+EA+RW +
Sbjct: 124 DYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPIAFQEFMIVPAGAPTFKEALRWGA 183

Query: 187 ETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALAL 246
           E +H LKK++  +    A  VGDEGGFAP      + ++ ++ AIE AGY PG+++ L  
Sbjct: 184 EIFHALKKILKSR--GLATAVGDEGGFAPRFDGTEDGVETILAAIEAAGYVPGKDVFLGF 241

Query: 247 DAASSEFYKDGKYIVSGKEY--------TREELLELYKELTSTYPIVSIEDPFHEEDWEG 298
           D ASSEFY   + +    ++        T +E ++  +EL + YPI++IED   E DW+G
Sbjct: 242 DCASSEFYDKERKVYDYTKFEGEGAAVRTADEQIDYLEELVNKYPIITIEDGMDENDWDG 301

Query: 299 FVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAF 358
           +  +T  LGKKVQ VGDD FVTN   L+KGI    AN++L+KVNQIGTLTE  DA  MA 
Sbjct: 302 WKKLTERLGKKVQPVGDDFFVTNTSYLEKGINEACANSILIKVNQIGTLTETFDAIEMAK 361

Query: 359 RAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVA 418
            AGY  VVSHRSGETED+TIAD+AVA NAGQIKTG+ +R+DR AKYNQL+RIE++L  VA
Sbjct: 362 EAGYTAVVSHRSGETEDSTIADIAVAANAGQIKTGSLSRTDRIAKYNQLLRIEDQLGEVA 421

Query: 419 VYAG 422
            Y G
Sbjct: 422 EYRG 425


>sp|Q43321|ENO_ALNGL ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|1041245|emb|CAA63121.1| (X92377)
           enolase [Alnus glutinosa]
           Length = 440
           
 Score =  458 bits (1167), Expect = e-128
 Identities = 253/438 (57%), Positives = 315/438 (71%), Gaps = 25/438 (5%)

Query: 8   EIVAVIAREILDSRGNPTVEVDVHTPISM-GRAAVPSGASTGTHEAVELRDGGKRYHGKG 66
           EI  + AR+I DSRGNPTVE +V T   +  RAAVPSGASTG +EA+ELRDGG  Y GKG
Sbjct: 3   EITHIKARQIFDSRGNPTVEAEVTTANGVVSRAAVPSGASTGVYEALELRDGGSDYLGKG 62

Query: 67  VRRAVENVNKIIAPELVGMDVRWQR--EIDRLLIELDGTEN-----KSNLGANAILAVSL 119
           V +AV+NVNKII P L+G D   Q   +ID +  +LDGT N     K  LGANAILAVSL
Sbjct: 63  VLKAVDNVNKIIGPALIGKDATEQTAIDIDFMFQQLDGTVNEWGWCKQKLGANAILAVSL 122

Query: 120 AVAKAAANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGAN 176
           AV KA A+  ++PLY++   L G    VLPVP  NVINGG HAGN L  QEFMI+P+GA+
Sbjct: 123 AVCKAGASVKKIPLYKHIANLAGNPKLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGAS 182

Query: 177 SFREAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGY 236
           SF+EA++   E YH LK VI +KYG++A NVGDEGGFAP ++E  E L++L  AI +AGY
Sbjct: 183 SFKEAMKMGVEVYHHLKAVIKKKYGQDATNVGDEGGFAPNIQENKEGLELLKTAIAKAGY 242

Query: 237 KPGEEIALALDAASSEFYKDGKYIVSGKE--------YTREELLELYKELTSTYPIVSIE 288
                + + +D A+SEFY+  K I + KE         + ++L +LYK     YPIVSIE
Sbjct: 243 -----VVIGMDVAASEFYEKDKDITNFKEENNDGSQKISADQLKDLYKSFVDEYPIVSIE 297

Query: 289 DPFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLT 348
           DPF ++DWE +  +T E+G+KVQIVGDDL VTNPKR++K I+  A NALLLKVNQIG++T
Sbjct: 298 DPFDQDDWEHYSKLTAEIGEKVQIVGDDLLVTNPKRVEKAIKEKACNALLLKVNQIGSVT 357

Query: 349 EAMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLI 408
           E+++A  M+ RAG+G V++HRSGETED  IADL+V L  GQIKTGAP RS+R AKYNQL+
Sbjct: 358 ESIEAVKMSKRAGWG-VMAHRSGETEDTFIADLSVGLATGQIKTGAPCRSERLAKYNQLL 416

Query: 409 RIEEELEGVAVYAGKNFR 426
           RIEEEL   AVYAG NFR
Sbjct: 417 RIEEELGSEAVYAGANFR 434


>emb|CAC00533.1| (AJ132581) enolase, isoform 2 [Hevea brasiliensis]
           Length = 445
           
 Score =  458 bits (1166), Expect = e-128
 Identities = 255/437 (58%), Positives = 312/437 (71%), Gaps = 21/437 (4%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPIS-MGRAAVPSGASTGTHEAVELRDGGKRYHGKGV 67
           IV+V AR+I DSRGNPTVE DV      + RAAVP GASTG +EA+ELRDGG  Y GKGV
Sbjct: 5   IVSVRARQIFDSRGNPTVEADVKLSDGYLARAAVPRGASTGIYEALELRDGGSDYLGKGV 64

Query: 68  RRAVENVNKIIAPELVGMDVRWQREIDRLLIE-LDGTEN-----KSNLGANAILAVSLAV 121
            +AVENVN II P LVG D   Q  ID  +++ LDGT N     K  LGANAILAVSLAV
Sbjct: 65  SKAVENVNIIIGPALVGKDPTDQVGIDNFMVQQLDGTVNEWGWCKQKLGANAILAVSLAV 124

Query: 122 AKAAANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSF 178
            KA A+   +PLY++   L G    VLPVP  NVINGG HAGN L  QEFMI+P+GA+SF
Sbjct: 125 CKAGAHVKGIPLYKHVANLAGNKNLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSF 184

Query: 179 REAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKP 238
           +EA++  +E YH LK VI +KYG++A NVGDEGGFAP ++E  E L++L  AI +AGY  
Sbjct: 185 KEAMKMGAEVYHHLKSVIKKKYGQDATNVGDEGGFAPNIQENKEGLELLKTAIAKAGYTG 244

Query: 239 GEEIALALDAASSEFY-KDGKYIVSGKEYTR--------EELLELYKELTSTYPIVSIED 289
             ++ + +D A+SEFY  D  Y ++ KE           + L +LYK   + YPIVSIED
Sbjct: 245 --KVVIGMDVAASEFYGSDKTYDLNFKEENNNGSQKISGDVLKDLYKSFVTEYPIVSIED 302

Query: 290 PFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTE 349
           PF ++DWE +  +T E+G KVQIVGDDL VTNPKR++K I+  A NALLLKVNQIG++TE
Sbjct: 303 PFDQDDWEHYAKLTSEIGVKVQIVGDDLLVTNPKRVEKAIKEKACNALLLKVNQIGSVTE 362

Query: 350 AMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIR 409
           +++A  M+ RAG+GV+ SHRSGETED  IADL+V L  GQIKTGAP RS+R AKYNQL+R
Sbjct: 363 SIEAVKMSKRAGWGVMASHRSGETEDTFIADLSVGLATGQIKTGAPCRSERLAKYNQLLR 422

Query: 410 IEEELEGVAVYAGKNFR 426
           IEEEL   AVYAG NFR
Sbjct: 423 IEEELGAEAVYAGANFR 439


>gb|AAD41643.1|AF072586_1 (AF072586) alpha enolase [Alligator mississippiensis]
           Length = 434
           
 Score =  458 bits (1165), Expect = e-128
 Identities = 245/431 (56%), Positives = 309/431 (70%), Gaps = 17/431 (3%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67
           I+ + AREI DSRGNPTVEVD++T   + RAAVPSGASTG +EA+ELRD  K R+ GKGV
Sbjct: 3   ILKIHAREIFDSRGNPTVEVDLYTSKGLFRAAVPSGASTGIYEALELRDNDKTRFMGKGV 62

Query: 68  RRAVENVNKIIAPELVGMDVRW--QREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
            +AV +VNK IAP L+  ++    Q +IDRL++E+DG+ENKS  GANAIL VSLAV KA 
Sbjct: 63  SKAVAHVNKTIAPALISKNISVVEQEKIDRLMLEMDGSENKSKFGANAILGVSLAVCKAG 122

Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182
           A    +PLY++   L G    +LPVP  NVINGG HAGN L  QEFMI+P+GA SF+EA+
Sbjct: 123 AAEKGVPLYRHIADLAGNPEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFKEAM 182

Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242
           R  +E YH LK VI EKYGK+A NVGDEGGFAP + E  E L++L  AI +AGY   ++I
Sbjct: 183 RIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKNAINKAGYS--DKI 240

Query: 243 ALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEED 295
            + +D A+SEFY+DGKY +  K         T ++L +LYK     YP+VSIEDPF ++D
Sbjct: 241 VIGMDVAASEFYRDGKYDLDFKSPDDPSRYITPDQLADLYKSFVKNYPVVSIEDPFDQDD 300

Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355
           W  +   T  +G  +Q+VGDDL VTNPKR+ K ++  A N LLLKVNQIG++TE++ A  
Sbjct: 301 WAAWKKFTASVG--IQVVGDDLTVTNPKRIAKAVDDKACNCLLLKVNQIGSVTESLQACK 358

Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415
           +A   G+GV+VSHRSGETED  IADL V L  GQIKTGAP RS+R AKYNQ++RIEEEL 
Sbjct: 359 LAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEELG 418

Query: 416 GVAVYAGKNFR 426
             A +AG+NFR
Sbjct: 419 SKARFAGRNFR 429


>sp|P08734|ENO_XENLA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|68307|pir||NOXL phosphopyruvate
           hydratase (EC 4.2.1.11) ENO1 - African clawed frog
           >gi|64680|emb|CAA68706.1| (Y00718) enolase (AA 1-434)
           [Xenopus laevis]
           Length = 434
           
 Score =  457 bits (1164), Expect = e-128
 Identities = 249/430 (57%), Positives = 307/430 (70%), Gaps = 17/430 (3%)

Query: 14  AREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRAVE 72
           AREI DSRGNPTVEVD++T   + RAAVPSGASTG +EA+ELRD  K RY GKGV RAV+
Sbjct: 8   AREIFDSRGNPTVEVDLYTCKGLFRAAVPSGASTGIYEALELRDNDKTRYLGKGVGRAVK 67

Query: 73  NVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANALE 130
            VN+ + P L    ++V  Q +ID+L+IE+DGTENKS  GANA+L VSLAV KA A    
Sbjct: 68  YVNEFLGPALCTQNLNVVEQEKIDKLMIEMDGTENKSKFGANALLGVSLAVCKAGAAEKG 127

Query: 131 LPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVSE 187
           +PLY++   L G    +LPVP  NVINGG HAGN L  QEFMI+P+GA+SF+EA+R  +E
Sbjct: 128 VPLYRHIADLAGNPEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGADSFKEAMRIGAE 187

Query: 188 TYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALALD 247
            YH LK VI EKYGK+A NVGDEGGFAP + E  E L++L  AI +AGY   ++I + +D
Sbjct: 188 VYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKTAINKAGYP--DKIVIGMD 245

Query: 248 AASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEEDWEGFV 300
            A+SEFY+DGKY +  K         + ++L ELY      YP+VSIEDPF ++ WE + 
Sbjct: 246 VAASEFYRDGKYDLDFKSPDDPSRYISPDKLAELYMSFVKNYPVVSIEDPFDQDHWEAWT 305

Query: 301 MITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRA 360
             T   G  +Q+VGDDL VTNPKR+ K +E  A N LLLKVNQIGT+TE+++A  +A   
Sbjct: 306 KFTAASG--IQVVGDDLTVTNPKRIAKAVEEKACNCLLLKVNQIGTVTESLEACKLAQSN 363

Query: 361 GYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVY 420
           G+GV+VSHRSGETED  IADL V L  GQIKTGAP RS+R AKYNQL+RIEEEL   A +
Sbjct: 364 GWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGSKARF 423

Query: 421 AGKNFRKVFF 430
           AGKNFRK  F
Sbjct: 424 AGKNFRKPVF 433


>sp|P51913|ENOA_CHICK ALPHA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (PHOSPHOPYRUVATE
           HYDRATASE) >gi|1085243|pir||JC4186 phosphopyruvate
           hydratase (EC 4.2.1.11) alpha chain - chicken
           >gi|974176|dbj|BAA07132.1| (D37900) enolase [Gallus
           gallus]
           Length = 434
           
 Score =  456 bits (1160), Expect = e-127
 Identities = 245/431 (56%), Positives = 310/431 (71%), Gaps = 17/431 (3%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67
           I+ + AREI DSRGNPTVEVD++T   + RAAVPSGASTG +EA+ELRD  K RY GKGV
Sbjct: 3   ILKIHAREIFDSRGNPTVEVDLYTNKGLFRAAVPSGASTGIYEALELRDNDKTRYLGKGV 62

Query: 68  RRAVENVNKIIAPELVGMDVRW--QREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
            +AVE+VNK IAP L+  +V    Q +ID+L++E+DGTENKS  GANAIL VSLAV KA 
Sbjct: 63  SKAVEHVNKTIAPALISKNVNVVEQEKIDKLMLEMDGTENKSKFGANAILGVSLAVCKAG 122

Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182
           A    +PLY++   L G    +LPVP  NVINGG HAGN L  QEFMI+P+GA++F+EA+
Sbjct: 123 AAEKGVPLYRHIADLAGNPEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGADTFKEAM 182

Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242
           R  +E YH LK VI EKYGK+A NVGDEGGFAP + E  E L++L  AI +AGY   +++
Sbjct: 183 RIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKTAIGKAGYS--DKV 240

Query: 243 ALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEED 295
            + +D A+SEFY+DGKY +  K         + ++L +LY      YP+VSIEDPF ++D
Sbjct: 241 VIGMDVAASEFYRDGKYDLDFKSPDDPSRYISPDQLADLYLGFVKNYPVVSIEDPFDQDD 300

Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355
           W  +   T  +G  +Q+VGDDL VTNPKR+ K +E  + N LLLKVNQIG++TE++ A  
Sbjct: 301 WAAWKKFTASVG--IQVVGDDLTVTNPKRIAKAVEEKSCNCLLLKVNQIGSVTESLQACK 358

Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415
           +A   G+GV+VSHRSGETED  IADL V L  GQIKTGAP RS+R AKYNQL+RIEEEL 
Sbjct: 359 LAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELG 418

Query: 416 GVAVYAGKNFR 426
             A +AG+NFR
Sbjct: 419 SKARFAGRNFR 429


>gb|AAD41645.1|AF072588_1 (AF072588) alpha enolase [Trachemys scripta elegans]
           Length = 434
           
 Score =  455 bits (1157), Expect = e-127
 Identities = 243/431 (56%), Positives = 310/431 (71%), Gaps = 17/431 (3%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67
           I+ + AREI DSRGNPTVEVD++T   + RAAVPSGASTG +EA+ELRD  K R+ GKGV
Sbjct: 3   ILKIFAREIFDSRGNPTVEVDLYTSKGLFRAAVPSGASTGIYEALELRDNDKTRFLGKGV 62

Query: 68  RRAVENVNKIIAPELVGMDVRW--QREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
            +AV +VNK IAP L+  ++    Q +ID+L++E+DG+ENKS  GANAIL VSLAV KA 
Sbjct: 63  SKAVGHVNKTIAPALISKNINVVEQEKIDKLMLEMDGSENKSKFGANAILGVSLAVCKAG 122

Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182
           A    +PLY++   L G    +LPVP  NVINGG HAGN L  QEFMI+P+GA SF+EA+
Sbjct: 123 AAEKGVPLYRHIADLAGNPEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFKEAM 182

Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242
           R  +E YH LK VI EKYGK+A NVGDEGGFAP + E  E L++L  AI +AGY   +++
Sbjct: 183 RIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILEDKEALELLKTAISKAGYT--DKV 240

Query: 243 ALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEED 295
            + +D A+SEFY+DGKY +  K         T ++L +LYK    +YP+VS+EDPF ++D
Sbjct: 241 VIGMDVAASEFYRDGKYDLDFKSPDDPSRYITPDQLADLYKSFIKSYPLVSVEDPFDQDD 300

Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355
           W  +   T  +G  VQ+VGDDL VTNPKR+ K +E  + N LLL+VNQIG++TE++ A  
Sbjct: 301 WSAWKKFTATVG--VQVVGDDLTVTNPKRIAKPVEEKSCNCLLLQVNQIGSVTESLQACK 358

Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415
           +A   G+GV+VSHRSGETED  IADL V L  GQIKTGAP RS+R AKYNQL+RIEEEL 
Sbjct: 359 LAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELG 418

Query: 416 GVAVYAGKNFR 426
             A +AG+NFR
Sbjct: 419 SKARFAGRNFR 429


>sp|O02654|ENO_LOLPE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|1911573|gb|AAB50731.1| (S80961) enolase
           [Loligo pealii=squids, nervous system, Peptide, 434 aa]
           [Loligo pealei]
           Length = 434
           
 Score =  454 bits (1156), Expect = e-127
 Identities = 248/432 (57%), Positives = 309/432 (71%), Gaps = 18/432 (4%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRD-GGKRYHGKGV 67
           I  V +R+I DSRGNPTVEVD+ T   M RAAVPSGASTG +EA+E+RD   K YHGK +
Sbjct: 3   IKKVHSRQIFDSRGNPTVEVDLWTDKGMFRAAVPSGASTGIYEALEMRDKDAKNYHGKTL 62

Query: 68  RRAVENVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
             AV NVNKIIAP LV   MD + Q  +D  L+ LDGTENK+ LGANAIL VSLAV KA 
Sbjct: 63  FNAVGNVNKIIAPALVDKKMDEKDQTAVDNFLLALDGTENKNKLGANAILGVSLAVCKAG 122

Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182
           A A  +PLY++   L G    +LPVP  NVINGG HAGN L  QEFMI+P GA +F EA+
Sbjct: 123 AAAKGVPLYRHIADLAGNKEVILPVPAFNVINGGSHAGNKLAMQEFMILPTGAKNFTEAM 182

Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242
           +  +E YH LK VI +KYG++A NVGDEGGFAP + +  E L++L  AI  AGY    EI
Sbjct: 183 KMGTEVYHHLKSVIKKKYGQDACNVGDEGGFAPNILDNKEGLELLKTAIANAGYTA--EI 240

Query: 243 ALALDAASSEFYKDGKYIVSGKE--------YTREELLELYKELTSTYPIVSIEDPFHEE 294
            + +D A+SEF K+ KY +  K          T ++L ++YK+    YP+VSIEDPF ++
Sbjct: 241 EIGMDVAASEFCKEKKYDLDFKNPDSNPNDWLTSDQLADVYKDFVKNYPVVSIEDPFDQD 300

Query: 295 DWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAA 354
           DWE +  +T+++   +QIVGDDL VTNPKR++KGI++ AANALLLKVNQIG++TE++ A 
Sbjct: 301 DWEAYTKMTKDMD--IQIVGDDLLVTNPKRVQKGIDLKAANALLLKVNQIGSVTESIQAC 358

Query: 355 YMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEEL 414
            M+  AG+GV+VSHRSGETED  IADL V L  GQIKTGAP RS+R AKYNQ++RIEEEL
Sbjct: 359 KMSQDAGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEEL 418

Query: 415 EGVAVYAGKNFR 426
              AV+AGK FR
Sbjct: 419 GDKAVFAGKKFR 430


>sp|P26301|ENO1_MAIZE ENOLASE 1 (2-PHOSPHOGLYCERATE DEHYDRATASE 1) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE 1) >gi|100869|pir||S16257 phosphopyruvate
           hydratase (EC 4.2.1.11) - maize
           >gi|22273|emb|CAA39454.1| (X55981) enolase [Zea mays]
           Length = 446
           
 Score =  453 bits (1154), Expect = e-126
 Identities = 252/438 (57%), Positives = 307/438 (69%), Gaps = 22/438 (5%)

Query: 9   IVAVIAREILDSRGNPTVEVDVH-TPISMGRAAVPSGASTGTHEAVELRDGGKRYHGKGV 67
           I  V AR+I DSRGNPTVEVDV  +  S  R AVPSGASTG +EA+ELRDGG  Y GKGV
Sbjct: 5   ITWVKARQIFDSRGNPTVEVDVGLSDGSYARGAVPSGASTGIYEALELRDGGSDYLGKGV 64

Query: 68  RRAVENVNKIIAPELVGMDVRWQREIDRLLIE-LDGTEN-----KSNLGANAILAVSLAV 121
            +AV NVN II P +VG D   Q EID  +++ LDGT N     K  LGANAILAVSLAV
Sbjct: 65  LKAVSNVNNIIGPAIVGKDPTEQVEIDNFMVQQLDGTSNEWGWCKQKLGANAILAVSLAV 124

Query: 122 AKAAANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSF 178
            KA A   ++PLYQ+   L G    VLPVP  NVINGG HAGN L  QEFMI+P GA+SF
Sbjct: 125 CKAGAMVKKIPLYQHIANLAGNKTLVLPVPAFNVINGGSHAGNKLAMQEFMILPTGASSF 184

Query: 179 REAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKP 238
           +EA++   E YH LK +I +KYG++A NVGDEGGFAP ++E  E L++L  AIE+AGY  
Sbjct: 185 KEAMKMGVEVYHNLKSIIKKKYGQDATNVGDEGGFAPNIQENKEGLELLKAAIEKAGYTG 244

Query: 239 GEEIALALDAASSEFY--KDGKYIVSGKEYTRE--------ELLELYKELTSTYPIVSIE 288
             ++ + +D A+SEF+  KD  Y ++ KE   +         L +LYK   S YPI SIE
Sbjct: 245 --KVVIGMDVAASEFFGEKDKTYDLNFKEENNDGSNKISGDSLKDLYKSFVSEYPIESIE 302

Query: 289 DPFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLT 348
           DPF ++DW  +  +T E+G+KVQIVGDDL VTNP R+ K I     NALLLKVNQIG++T
Sbjct: 303 DPFDQDDWSTYAKLTDEIGQKVQIVGDDLLVTNPTRVAKAINEKTCNALLLKVNQIGSVT 362

Query: 349 EAMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLI 408
           E+++A  M+ RAG+GV+ SHRSGETED  IADL+V L+ GQIKTGAP RS+R AKYNQL+
Sbjct: 363 ESIEAVRMSKRAGWGVMASHRSGETEDTFIADLSVGLSTGQIKTGAPCRSERLAKYNQLL 422

Query: 409 RIEEELEGVAVYAGKNFR 426
           RIEEEL   AVYAG  FR
Sbjct: 423 RIEEELGDAAVYAGAKFR 440


>sp|P19140|ENOA_ANAPL ALPHA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (TAU-CRYSTALLIN)
           >gi|86046|pir||A32132 phosphopyruvate hydratase (EC
           4.2.1.11) alpha - duck >gi|62456|emb|CAA32409.1|
           (X14195) tau-crystallin/ alpha-enolase [Anas
           platyrhynchos] >gi|213091|gb|AAA49218.1| (M20749)
           tau-crystallin/alpha-enolase (EC 4.2.1.11) [Anas
           platyrhynchos] >gi|226274|prf||1504281A tau crystallin
           [Anas platyrhynchos]
           Length = 434
           
 Score =  453 bits (1154), Expect = e-126
 Identities = 245/431 (56%), Positives = 309/431 (70%), Gaps = 17/431 (3%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67
           I+ + AREI DSRGNPTVEVD++T   + RAAVPSGASTG +EA+ELRD  K RY GKGV
Sbjct: 3   ILKIHAREIFDSRGNPTVEVDLYTNKGLFRAAVPSGASTGIYEALELRDNDKTRYMGKGV 62

Query: 68  RRAVENVNKIIAPELVGMDVRW--QREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
            +AVE++NK IAP L+  +V    Q +ID+L++++DG+ENKS  GANAIL VSLAV KA 
Sbjct: 63  SKAVEHINKTIAPALISKNVNVVEQDKIDKLMLDMDGSENKSKFGANAILGVSLAVCKAG 122

Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182
           A    +PLY++   L G    +LPVP  NVINGG HAGN L  QEFMI P GA+SF+EA+
Sbjct: 123 AAEKGVPLYRHIADLAGNPEVILPVPAFNVINGGSHAGNKLAMQEFMIPPCGADSFKEAM 182

Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242
           R  +E YH LK VI EKYGK+A NVGDEGGFAP + E  E L++L  AI +AGY   +++
Sbjct: 183 RIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKTAIGKAGYS--DKV 240

Query: 243 ALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEED 295
            + +D A+SEFY+DGKY +  K         + ++L +LYK     YP+VSIEDPF ++D
Sbjct: 241 VIGMDVAASEFYRDGKYDLDFKSPDDPSRYISPDQLADLYKGFVKNYPVVSIEDPFDQDD 300

Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355
           W  +   T  +G  +Q+VGDDL VTNPKR+ K +E  A N LLLKVNQIG++TE++ A  
Sbjct: 301 WGAWKKFTGSVG--IQVVGDDLTVTNPKRIAKAVEEKACNCLLLKVNQIGSVTESLQACK 358

Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415
           +A   G+GV+VSHRSGETED  IADL V L  GQIKTGAP RS+R AKYNQL+RIEEEL 
Sbjct: 359 LAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELG 418

Query: 416 GVAVYAGKNFR 426
             A +AG+NFR
Sbjct: 419 SKARFAGRNFR 429


>emb|CAA76735.1| (Y17298) enolase [Cunninghamella elegans]
           Length = 436
           
 Score =  453 bits (1154), Expect = e-126
 Identities = 251/434 (57%), Positives = 305/434 (69%), Gaps = 19/434 (4%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGKR-YHGKGV 67
           I  V AR+I DSRGNPTVEV+V T   + RA VPSGASTG HEA+ELRDG K  Y GKGV
Sbjct: 3   ITKVHARQIFDSRGNPTVEVEVTTDKGVFRAGVPSGASTGVHEALELRDGVKSDYLGKGV 62

Query: 68  RRAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
            +AV NVN II  ELV   + V  Q+ +D  LI+LDGTENK  LGANAIL VSLAVAKA 
Sbjct: 63  LKAVGNVNTIINEELVKANLSVVDQKAVDDFLIQLDGTENKEKLGANAILGVSLAVAKAG 122

Query: 126 ANALELPLYQYL----GGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREA 181
           A    +P Y ++    G    +VLPVP  NVINGG HAGN L  QEFMIMP GA SF EA
Sbjct: 123 AAEKGVPFYVHIADLAGSKKPFVLPVPAFNVINGGSHAGNKLAMQEFMIMPTGAKSFSEA 182

Query: 182 IRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEE 241
           ++  SE YH LKKVI EKYG++A NVGDEGGFAP +++  E L++L+ AIE+AGY    +
Sbjct: 183 MKLGSEVYHTLKKVINEKYGQDATNVGDEGGFAPNIQDNQEGLELLVTAIEKAGYTG--K 240

Query: 242 IALALDAASSEFYKDGKYIVSGKE--------YTREELLELYKELTSTYPIVSIEDPFHE 293
           I +A+D A+S+FYKDGKY +  K          T ++L +LY      YPIVSIED F +
Sbjct: 241 IKVAMDCAASDFYKDGKYDLDFKNPNSDPSTYLTGQDLTDLYNSYAGKYPIVSIEDAFDQ 300

Query: 294 EDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDA 353
           +DWE +  +        Q+VGDDL VTNPKR+   +E  A NALLLKVNQIGTLTE++ A
Sbjct: 301 DDWENWAHMNASAD--YQLVGDDLTVTNPKRIATAVEKKACNALLLKVNQIGTLTESIQA 358

Query: 354 AYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEE 413
           A  + +AG+GV+VSHRSGETED +IA + V L  GQIKTGAP RS+R AKYN+L+RIEEE
Sbjct: 359 ALDSQKAGWGVMVSHRSGETEDTSIASIVVGLRTGQIKTGAPCRSERLAKYNELLRIEEE 418

Query: 414 LEGVAVYAGKNFRK 427
           L   A+YAG++FRK
Sbjct: 419 LGDAAIYAGEHFRK 432


>sp|P42040|ENO_CLAHE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) (ALLERGEN CLA H 6) (CLA H VI)
           Length = 440
           
 Score =  453 bits (1154), Expect = e-126
 Identities = 249/435 (57%), Positives = 310/435 (71%), Gaps = 19/435 (4%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67
           I  + +R + DSRGNPTVEVD+ T   + RA VPSGASTG+HEA ELRDG K ++ GKGV
Sbjct: 3   ISKIHSRYVYDSRGNPTVEVDIVTETGLHRAIVPSGASTGSHEACELRDGDKSKWAGKGV 62

Query: 68  RRAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
            +AV NVN+IIAP L+   +DV+ Q  +D  L +LDGT NK+ +GANAIL VS+AVAKAA
Sbjct: 63  TKAVANVNEIIAPALIKENLDVKDQAAVDAFLNKLDGTTNKTKIGANAILGVSMAVAKAA 122

Query: 126 ANALELPLYQYLGGVNA----YVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREA 181
           A    +PLY ++  ++     +VLPVP  NV+NGG HAG  L FQEFMI+P GA SF EA
Sbjct: 123 AAEKRVPLYAHISDLSGTKKPFVLPVPFMNVVNGGSHAGGRLAFQEFMIVPSGAPSFTEA 182

Query: 182 IRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEE 241
           +R  +E Y  LK +  ++YG++A NVGDEGG AP ++   E LD++  AIEEAGY    +
Sbjct: 183 MRQGAEVYQKLKSLTKKRYGQSAGNVGDEGGVAPDIQTAEEALDLITDAIEEAGYTG--Q 240

Query: 242 IALALDAASSEFYK--DGKYIVSGKE--------YTREELLELYKELTSTYPIVSIEDPF 291
           I +A+D ASSEFYK  + KY +  K          T E+L + YK+L + YPIVSIEDPF
Sbjct: 241 IKIAMDVASSEFYKADEKKYDLDFKNPDSDKSKWITYEQLADQYKQLAAKYPIVSIEDPF 300

Query: 292 HEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAM 351
            E+DWE +    +  G   QIVGDDL VTNP+ +KK IE  A NALLLKVNQIGT+TEA+
Sbjct: 301 AEDDWEAWSYFYKTSGSDFQIVGDDLTVTNPEFIKKAIETKACNALLLKVNQIGTITEAI 360

Query: 352 DAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIE 411
           +AA  +F AG+GV+VSHRSGETED TIAD+ V L AGQIKTGAPARS+R AK NQ++RIE
Sbjct: 361 NAAKDSFAAGWGVMVSHRSGETEDVTIADIVVGLRAGQIKTGAPARSERLAKLNQILRIE 420

Query: 412 EELEGVAVYAGKNFR 426
           EEL   AVYAG NFR
Sbjct: 421 EELGDKAVYAGDNFR 435


>gi|4503571 enolase 1, (alpha); Enolase-1, alpha; phosphopyruvate hydratase;
           enolase 1, (alpha)-like 1 [Homo sapiens]
           >gi|11423101|ref|XP_001559.1| enolase 1, (alpha) [Homo
           sapiens] >gi|119339|sp|P06733|ENOA_HUMAN ALPHA ENOLASE
           (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (NON-NEURAL ENOLASE)
           (NNE) (PHOSPHOPYRUVATE HYDRATASE) >gi|87368|pir||A29170
           phosphopyruvate hydratase (EC 4.2.1.11) alpha - human
           >gi|182114|gb|AAA52387.1| (M14328) alpha enolase (EC
           4.2.1.11) [Homo sapiens] >gi|1167843|emb|CAA34360.1|
           (X16288) alpha-enolase [Homo sapiens]
           Length = 434
           
 Score =  453 bits (1153), Expect = e-126
 Identities = 245/431 (56%), Positives = 308/431 (70%), Gaps = 17/431 (3%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67
           I+ + AREI DSRGNPTVEVD+ T   + RAAVPSGASTG +EA+ELRD  K RY GKGV
Sbjct: 3   ILKIHAREIFDSRGNPTVEVDLFTSKGLFRAAVPSGASTGIYEALELRDNDKTRYMGKGV 62

Query: 68  RRAVENVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
            +AVE++NK IAP LV   ++V  Q +ID+L+IE+DGTENKS  GANAIL VSLAV KA 
Sbjct: 63  SKAVEHINKTIAPALVSKKLNVTEQEKIDKLMIEMDGTENKSKFGANAILGVSLAVCKAG 122

Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182
           A    +PLY++   L G +  +LPVP  NVINGG HAGN L  QEFMI+P+GA +FREA+
Sbjct: 123 AVEKGVPLYRHIADLAGNSEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGAANFREAM 182

Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242
           R  +E YH LK VI EKYGK+A NVGDEGGFAP + E  E L++L  AI +AGY   +++
Sbjct: 183 RIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEGLELLKTAIGKAGYT--DKV 240

Query: 243 ALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEED 295
            + +D A+SEF++ GKY +  K         + ++L +LYK     YP+VSIEDPF ++D
Sbjct: 241 VIGMDVAASEFFRSGKYDLDFKSPDDPSRYISPDQLADLYKSFIKDYPVVSIEDPFDQDD 300

Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355
           W  +   T   G  +Q+VGDDL VTNPKR+ K +   + N LLLKVNQIG++TE++ A  
Sbjct: 301 WGAWQKFTASAG--IQVVGDDLTVTNPKRIAKAVNEKSCNCLLLKVNQIGSVTESLQACK 358

Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415
           +A   G+GV+VSHRSGETED  IADL V L  GQIKTGAP RS+R AKYNQL+RIEEEL 
Sbjct: 359 LAQANGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELG 418

Query: 416 GVAVYAGKNFR 426
             A +AG+NFR
Sbjct: 419 SKAKFAGRNFR 429


>gb|AAF13454.1|AF205070_1 (AF205070) enolase [Mastigamoeba balamuthi]
           Length = 439
           
 Score =  453 bits (1152), Expect = e-126
 Identities = 246/436 (56%), Positives = 313/436 (71%), Gaps = 18/436 (4%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67
           I +V AREILDSRGNPTVEVD+ T   + R+AVPSGASTG +EA ELRDG K RY GKGV
Sbjct: 4   IKSVFAREILDSRGNPTVEVDLTTEKGLFRSAVPSGASTGIYEACELRDGDKSRYLGKGV 63

Query: 68  RRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAAN 127
            +AVENVNKI+AP+L+G+DV  Q EIDRL++++DGTENK++LGANAIL  S++V +AAA 
Sbjct: 64  LKAVENVNKILAPKLIGLDVTKQGEIDRLMLQIDGTENKTHLGANAILGCSMSVCRAAAA 123

Query: 128 ALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRW 184
              LPLY+Y   L G  + +LP+P  NVINGG HAGN L  QEFMI P GA SF EA+R 
Sbjct: 124 FRGLPLYRYIAELSGNKSPMLPLPCFNVINGGEHAGNKLAMQEFMICPTGATSFHEALRM 183

Query: 185 VSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIAL 244
            +ETYH LK VI ++YG +A NVGDEGGFAP ++   E L+++++AI++AGY    +I +
Sbjct: 184 AAETYHNLKLVIKKRYGMDATNVGDEGGFAPNIQANHEGLELIVEAIKQAGYTG--KIEI 241

Query: 245 ALDAASSEFY--KDGKYIVSGKE----------YTREELLELYKELTSTYPIVSIEDPFH 292
            +D A+S F+  K+ KY +  K            + E L++LY+E TS YPI SIEDPF 
Sbjct: 242 GMDVAASSFWDAKESKYDLGFKVPADKKTPDMLVSGEGLIKLYEEWTSKYPIWSIEDPFD 301

Query: 293 EEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMD 352
           ++DW  +   T  +  ++QIVGDDL VTNPKR+ +     A NALLLK+NQIG+++EA++
Sbjct: 302 QDDWATYTRFTELIRNRIQIVGDDLLVTNPKRIVEARNKKACNALLLKLNQIGSVSEAVE 361

Query: 353 AAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEE 412
           A  +A    +GV+VSHRSGETEDA IADL V L  GQIKTGAP RS+R AKYNQL+RIEE
Sbjct: 362 ACRLAREVNWGVMVSHRSGETEDAFIADLVVGLGCGQIKTGAPCRSERLAKYNQLLRIEE 421

Query: 413 ELEGVAVYAGKNFRKV 428
           EL   A YA K    V
Sbjct: 422 ELGANAHYAAKTLSGV 437


>emb|CAA57795.1| (X82400) enolase [Escherichia coli]
           Length = 437
           
 Score =  453 bits (1152), Expect = e-126
 Identities = 245/416 (58%), Positives = 303/416 (71%), Gaps = 11/416 (2%)

Query: 8   EIVAVIAREILDSRGNPTVEVDVHTPIS-MGRAAVPSGASTGTHEAVELRDGGK-RYHGK 65
           +IV +I REI+DSRGNPTVE +VH     +G AA PSGASTG+ EA+ELRDG K R+ GK
Sbjct: 3   KIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGK 62

Query: 66  GVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
           GV +AV  VN  IA  L+G D + Q  ID+++I+LDGTE KS  GANAILAVSLA AKAA
Sbjct: 63  GVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTEKKSKFGANAILAVSLANAKAA 122

Query: 126 ANALELPLYQYLGGVNA----YVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREA 181
           A A  +PLY+++  +N     Y +PVP+ N+INGG HA N++D QEFMI P+GA + +EA
Sbjct: 123 AAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEA 182

Query: 182 IRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEE 241
           IR  SE +H L KV+  K G N   VGDEGG+AP +    E L V+ +A++ AGY+ G++
Sbjct: 183 IRMGSEVFHHLAKVLKAK-GMNTA-VGDEGGYAPNLGSNDEALAVIAEAVKAAGYELGKD 240

Query: 242 IALALDAASSEFYKDGKYIVSG---KEYTREELLELYKELTSTYPIVSIEDPFHEEDWEG 298
           I LA+D A+SEFYKDGKY+++G   K +T EE     +ELT  YPIVSIED   E DW+G
Sbjct: 241 ITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDG 300

Query: 299 FVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAF 358
           F   T+ LG K+Q+VGDDLFVTN K LK+GIE G AN+ L+K NQIG+LTE + A  MA 
Sbjct: 301 FAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSYLIKFNQIGSLTETLAAIKMAK 360

Query: 359 RAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEEL 414
            AGY  V+SHRSGETEDATIADLAV   AGQIKTG+ +RSDR AKYNQLIRIEE L
Sbjct: 361 DAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEAL 416


>sp|P17182|ENOA_MOUSE ALPHA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (NON-NEURAL
           ENOLASE) (NNE) >gi|109803|pir||S10246 phosphopyruvate
           hydratase (EC 4.2.1.11) alpha - mouse
           >gi|55491|emb|CAA36605.1| (X52379) alpha-enolase (AA
           1-434) [Mus sp.]
           Length = 434
           
 Score =  451 bits (1149), Expect = e-126
 Identities = 245/431 (56%), Positives = 307/431 (70%), Gaps = 17/431 (3%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67
           I+ + AREI DSRGNPTVEVD++T   + RAAVPSGASTG +EA+ELRD  K R+ GKGV
Sbjct: 3   ILRIHAREIFDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDNDKTRFMGKGV 62

Query: 68  RRAVENVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
            +AVE++NK IAP LV   ++V  Q +ID+L+IE+DGTENKS  GANAIL VSLAV KA 
Sbjct: 63  SQAVEHINKTIAPALVSKKVNVVEQEKIDKLMIEMDGTENKSKFGANAILGVSLAVCKAG 122

Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182
           A    +PLY++   L G    +LPVP  NVINGG HAGN L  QEFMI+P+GA+SFREA+
Sbjct: 123 AVEKGVPLYRHIADLAGNPEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFREAM 182

Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242
           R  +E YH LK VI EKYGK+A NVGDEGGFAP + E  E L++L  AI +AGY   +++
Sbjct: 183 RIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKTAIAKAGYT--DQV 240

Query: 243 ALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEED 295
            + +D A+SEFY+ GKY +  K         T ++L +LYK     YP+VSIEDPF ++D
Sbjct: 241 VIGMDVAASEFYRSGKYDLDFKSPDDPSRYITPDQLADLYKSFVQNYPVVSIEDPFDQDD 300

Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355
           W  +   T   G  +Q+VGDDL VTNPKR+ K     + N LLLKVNQIG++TE++ A  
Sbjct: 301 WGAWQKFTASAG--IQVVGDDLTVTNPKRIAKAASEKSCNCLLLKVNQIGSVTESLQACK 358

Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415
            A   G+GV+VSHRSGETED  IADL V L  GQIKTGAP RS+R AKYNQ++RIEEEL 
Sbjct: 359 PAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEELG 418

Query: 416 GVAVYAGKNFR 426
             A +AG++FR
Sbjct: 419 SKAKFAGRSFR 429


>pir||S06756 phosphopyruvate hydratase (EC 4.2.1.11) beta - human
           >gi|31170|emb|CAA34513.1| (X16504) beta-enoiase (AA
           1-434) [Homo sapiens]
           Length = 434
           
 Score =  451 bits (1148), Expect = e-126
 Identities = 245/428 (57%), Positives = 304/428 (70%), Gaps = 17/428 (3%)

Query: 12  VIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRA 70
           + AREILDSRGNPTVEVD+HT     RAAVPSGASTG +EA+ELRDG K RY GKGV +A
Sbjct: 6   IFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKGRYLGKGVLKA 65

Query: 71  VENVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANA 128
           VEN+N  + P L+   + V  Q ++D+ +IELDGTENKS  GANAIL VSLAV KA A  
Sbjct: 66  VENINNTLGPALLQKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAE 125

Query: 129 LELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWV 185
             +PLY++   L G    +LPVP  NVINGG HAGN+L  QEFMI+P+GA+SF+EA+R  
Sbjct: 126 KGVPLYRHIADLAGNPDLILPVPAFNVINGGSHAGNNLAMQEFMILPVGASSFKEAMRIG 185

Query: 186 SETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALA 245
           +E YH LK VI  KYGK+A NVGDEGGFAP + E  E L++L  AI+ AGY   +++ + 
Sbjct: 186 AEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYP--DKVVIG 243

Query: 246 LDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEEDWEG 298
           +D A+SEFY++GKY +  K         T E+L ELYK     YP+VSIEDPF ++DW  
Sbjct: 244 MDVAASEFYRNGKYDLDFKSPDDPARHITGEKLGELYKSFIKNYPVVSIEDPFDQDDWAT 303

Query: 299 FVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAF 358
           +       G  +QIVGDDL VTNPKR+ + +E  A N LLLKVNQIG++TE++ A  +A 
Sbjct: 304 WTSFLS--GVNIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQ 361

Query: 359 RAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVA 418
             G+GV+VSHRSGETED  IADL V L  GQIKTGAP RS+R AKYNQL+RIEE L   A
Sbjct: 362 SNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKA 421

Query: 419 VYAGKNFR 426
           ++AG+ FR
Sbjct: 422 IFAGRKFR 429


>gi|4503573 enolase 3, (beta, muscle); Enolase-3, beta, muscle [Homo sapiens]
           >gi|34789|emb|CAA36216.1| (X51957) muscle-specific
           enolase [Homo sapiens]
           Length = 434
           
 Score =  451 bits (1148), Expect = e-126
 Identities = 245/428 (57%), Positives = 303/428 (70%), Gaps = 17/428 (3%)

Query: 12  VIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRA 70
           + AREILDSRGNPTVEVD+HT     RAAVPSGASTG +EA+ELRDG K RY GKGV +A
Sbjct: 6   IFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKGRYLGKGVLKA 65

Query: 71  VENVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANA 128
           VEN+N  + P L+   + V  Q ++D+ +IELDGTENKS  GANAIL VSLAV KA A  
Sbjct: 66  VENINNTLGPALLQKKLSVADQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAE 125

Query: 129 LELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWV 185
             +PLY++   L G    +LPVP  NVINGG HAGN L  QEFMI+P+GA+SF+EA+R  
Sbjct: 126 KGVPLYRHIADLAGNPDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEAMRIG 185

Query: 186 SETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALA 245
           +E YH LK VI  KYGK+A NVGDEGGFAP + E  E L++L  AI+ AGY   +++ + 
Sbjct: 186 AEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYP--DKVVIG 243

Query: 246 LDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEEDWEG 298
           +D A+SEFY++GKY +  K         T E+L ELYK     YP+VSIEDPF ++DW  
Sbjct: 244 MDVAASEFYRNGKYDLDFKSPDDPARHITGEKLGELYKSFIKNYPVVSIEDPFDQDDWAT 303

Query: 299 FVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAF 358
           +       G  +QIVGDDL VTNPKR+ + +E  A N LLLKVNQIG++TE++ A  +A 
Sbjct: 304 WTSFLS--GVNIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQ 361

Query: 359 RAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVA 418
             G+GV+VSHRSGETED  IADL V L  GQIKTGAP RS+R AKYNQL+RIEE L   A
Sbjct: 362 SNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKA 421

Query: 419 VYAGKNFR 426
           ++AG+ FR
Sbjct: 422 IFAGRKFR 429


>sp|P33676|ENO_SCHJA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|349802|gb|AAA29874.1| (L23324) enolase
           [Schistosoma japonicum]
           Length = 434
           
 Score =  451 bits (1148), Expect = e-126
 Identities = 249/432 (57%), Positives = 307/432 (70%), Gaps = 18/432 (4%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRD-GGKRYHGKGV 67
           I+A+ AR+I DSRGNPTVEVD+ T   + RAAVPSGASTG HEA+ELRD   K Y  KGV
Sbjct: 3   IIAIHARQIFDSRGNPTVEVDLKTAKGLFRAAVPSGASTGVHEALELRDTNSKAYMCKGV 62

Query: 68  RRAVENVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
             AV NVN IIAP L+   + V  Q E+D+ +IELDG ENK NLGANAIL VSLAV KA 
Sbjct: 63  LTAVSNVNNIIAPALLKKQIPVTNQSEVDQFMIELDGKENKGNLGANAILGVSLAVCKAG 122

Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182
           A  L LPLY+Y   L G    ++PVP  NVINGG HAGN L  QEFMI+P GA+SF EA+
Sbjct: 123 AAELNLPLYRYIAKLAGHKDVIMPVPAFNVINGGSHAGNKLAMQEFMILPTGASSFTEAM 182

Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242
           +  SE YH LK VI  ++G +A NVGDEGGFAP +++  + L +L +AI+ AGY    EI
Sbjct: 183 QMGSEVYHNLKAVIKREFGLDACNVGDEGGFAPNIQDNMKGLQLLEEAIKIAGYTGKVEI 242

Query: 243 ALALDAASSEFYKDGKYIVSGKE--------YTREELLELYKELTSTYPIVSIEDPFHEE 294
            +  D A+SE+YK GKY +  K          + +E+  +YKE+   YPIVSIEDPF ++
Sbjct: 243 GM--DCAASEYYKKGKYDLDFKNPQSAESHWLSPDEMANVYKEMIQKYPIVSIEDPFDQD 300

Query: 295 DWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAA 354
           DW+ +  +T      +QIVGDDL VTNPKR++K I++ A N LLLKVNQIG++TE+++A 
Sbjct: 301 DWDAWPKLTASTN--IQIVGDDLTVTNPKRIEKAIKVKACNCLLLKVNQIGSITESIEAC 358

Query: 355 YMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEEL 414
            MA +AG+GV+VSHRSGETED  IADL V L  GQIKTGAP RS+R AKYNQL+RIEEEL
Sbjct: 359 KMAQKAGWGVMVSHRSGETEDNFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEEL 418

Query: 415 EGVAVYAGKNFR 426
              A YAGK+FR
Sbjct: 419 GSTAKYAGKHFR 430


>emb|CAA59331.1| (X84907) carbonate dehydratase [Homo sapiens]
           Length = 434
           
 Score =  451 bits (1148), Expect = e-126
 Identities = 245/431 (56%), Positives = 307/431 (70%), Gaps = 17/431 (3%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67
           I+ + AREI DSRGNPTVEVD+ T   + RAAVPSGASTG +EA+ELRD  K RY GKGV
Sbjct: 3   ILKIHAREIFDSRGNPTVEVDLFTSKGLFRAAVPSGASTGIYEALELRDNDKTRYMGKGV 62

Query: 68  RRAVENVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
            +AVE++NK IAP LV   ++V  Q +ID+L+IE+DGTENKS  GANAIL VSLAV KA 
Sbjct: 63  SKAVEHINKTIAPALVSKKLNVTEQEKIDKLMIEMDGTENKSKFGANAILGVSLAVCKAG 122

Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182
           A    +PLY++   L G +  +LPVP  NVINGG HAGN L  QEFMI+P+GA +FREA+
Sbjct: 123 AVEKGVPLYRHIADLAGNSEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGAANFREAM 182

Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242
           R  +E YH LK VI EKYGK+A NVGDEGGFAP + E  E L++L  AI +AGY   +++
Sbjct: 183 RIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEGLELLKTAIGKAGYT--DKV 240

Query: 243 ALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEED 295
            + +D A+SEF + GKY +  K         + ++L +LYK     YP+VSIEDPF ++D
Sbjct: 241 VIGMDVAASEFSRSGKYDLDFKSPDDPSRYISPDQLADLYKSFIKDYPVVSIEDPFDQDD 300

Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355
           W  +   T   G  +Q+VGDDL VTNPKR+ K +   + N LLLKVNQIG++TE++ A  
Sbjct: 301 WGAWQKFTASAG--IQVVGDDLTVTNPKRIAKAVNEKSCNCLLLKVNQIGSVTESLQACK 358

Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415
           +A   G+GV+VSHRSGETED  IADL V L  GQIKTGAP RS+R AKYNQL+RIEEEL 
Sbjct: 359 LAQANGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELG 418

Query: 416 GVAVYAGKNFR 426
             A +AG+NFR
Sbjct: 419 SKAKFAGRNFR 429


>gi|11426964 enolase 3, (beta, muscle) [Homo sapiens]
           >gi|416950|sp|P13929|ENOB_HUMAN BETA ENOLASE
           (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (SKELETAL MUSCLE
           ENOLASE) (MSE) >gi|31167|emb|CAA40163.1| (X56832) muscle
           specific enolase [Homo sapiens]
           Length = 434
           
 Score =  450 bits (1146), Expect = e-125
 Identities = 245/428 (57%), Positives = 303/428 (70%), Gaps = 17/428 (3%)

Query: 12  VIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRA 70
           + AREILDSRGNPTVEVD+HT     RAAVPSGASTG +EA+ELRDG K RY GKGV +A
Sbjct: 6   IFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKGRYLGKGVLKA 65

Query: 71  VENVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANA 128
           VEN+N  + P L+   + V  Q ++D+ +IELDGTENKS  GANAIL VSLAV KA A  
Sbjct: 66  VENINNTLGPALLQKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAE 125

Query: 129 LELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWV 185
             +PLY++   L G    +LPVP  NVINGG HAGN L  QEFMI+P+GA+SF+EA+R  
Sbjct: 126 KGVPLYRHIADLAGNPDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEAMRIG 185

Query: 186 SETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALA 245
           +E YH LK VI  KYGK+A NVGDEGGFAP + E  E L++L  AI+ AGY   +++ + 
Sbjct: 186 AEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYP--DKVVIG 243

Query: 246 LDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEEDWEG 298
           +D A+SEFY++GKY +  K         T E+L ELYK     YP+VSIEDPF ++DW  
Sbjct: 244 MDVAASEFYRNGKYDLDFKSPDDPARHITGEKLGELYKSFIKNYPVVSIEDPFDQDDWAT 303

Query: 299 FVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAF 358
           +       G  +QIVGDDL VTNPKR+ + +E  A N LLLKVNQIG++TE++ A  +A 
Sbjct: 304 WTSFLS--GVNIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQ 361

Query: 359 RAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVA 418
             G+GV+VSHRSGETED  IADL V L  GQIKTGAP RS+R AKYNQL+RIEE L   A
Sbjct: 362 SNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKA 421

Query: 419 VYAGKNFR 426
           ++AG+ FR
Sbjct: 422 IFAGRKFR 429


>sp|Q27527|ENO_CAEEL ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|7508094|pir||T25040 hypothetical
           protein T21B10.2 - Caenorhabditis elegans
           >gi|3879986|emb|CAA92692.1| (Z68318) contains similarity
           to Pfam domain: PF00113 (Enol-ase), Score=1030.7,
           E-value=0, N=1~cDNA EST EMBL:Z14384 comes from this
           gene~cDNA EST EMBL:T02304 comes from this gene~cDNA EST
           yk99b2.5 comes from this gene~cDNA EST yk55g12.5 comes
           from this >
           Length = 434
           
 Score =  450 bits (1146), Expect = e-125
 Identities = 247/432 (57%), Positives = 307/432 (70%), Gaps = 18/432 (4%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGKRYH-GKGV 67
           I  + AR+I DSRGNPTVEVD+ T   + RAAVPSGASTG HEA+ELRDG K  H GKGV
Sbjct: 3   ITKIHARQIYDSRGNPTVEVDLFTEKGVFRAAVPSGASTGVHEALELRDGDKAVHLGKGV 62

Query: 68  RRAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
            +AV N+N+ IAP L+  G DV  Q++ID  ++ LDG+ENK NLGANAIL VSLAVAKA 
Sbjct: 63  LKAVSNINEKIAPALIAKGFDVTAQKDIDDFMMALDGSENKGNLGANAILGVSLAVAKAG 122

Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182
           A    LPLY+Y   L G    VLPVP  NVINGG HAGN L  QEFMI+P+GA+SF EA+
Sbjct: 123 AVHKGLPLYKYIAELAGTGKVVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFAEAM 182

Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242
           R  SE YH LK  I ++YG +A  VGDEGGFAP +++  E LD+L  AI++AGY    +I
Sbjct: 183 RMGSEVYHHLKAEIKKRYGLDATAVGDEGGFAPNIQDNKEGLDLLNTAIDKAGYTG--KI 240

Query: 243 ALALDAASSEFYKDGKYIV--------SGKEYTREELLELYKELTSTYPIVSIEDPFHEE 294
           ++ +D A+SEF+KDGKY +        S K  + E+L ELY+     YP+VSIED F ++
Sbjct: 241 SIGMDVAASEFFKDGKYDLDFKNPASDSSKWLSGEQLTELYQSFIKEYPVVSIEDAFDQD 300

Query: 295 DWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAA 354
           DW+ +          +Q+VGDDL VTNPKR++  I+  + N LLLKVNQIG++TE+++AA
Sbjct: 301 DWDNWGKFHG--ATSIQLVGDDLTVTNPKRIQTAIDKKSCNCLLLKVNQIGSVTESIEAA 358

Query: 355 YMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEEL 414
            ++   G+GV+VSHRSGETED  IADL V L  GQIKTGAP RS+R AKYNQL+RIEEEL
Sbjct: 359 KLSRANGWGVMVSHRSGETEDTFIADLVVGLATGQIKTGAPCRSERLAKYNQLLRIEEEL 418

Query: 415 EGVAVYAGKNFR 426
              AVYAG NFR
Sbjct: 419 GADAVYAGHNFR 430


>gb|AAD41644.1|AF072587_1 (AF072587) alpha enolase [Sceloporus undulatus]
           Length = 434
           
 Score =  450 bits (1145), Expect = e-125
 Identities = 244/431 (56%), Positives = 307/431 (70%), Gaps = 17/431 (3%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67
           I+ + AREI DSRGNPTVEVD++T   + RAAVPSGASTG +EA+ELRD  K R+ GKGV
Sbjct: 3   ILKLHAREIFDSRGNPTVEVDLYTNKGLFRAAVPSGASTGIYEALELRDNDKTRFLGKGV 62

Query: 68  RRAVENVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
            +AVE+VNK IAP LV   ++V  Q +ID+L++E+DGTENKS  GANAIL VSLAV KA 
Sbjct: 63  SKAVEHVNKTIAPALVNKKVNVVEQEKIDKLMLEMDGTENKSKFGANAILGVSLAVCKAG 122

Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182
           A    +PLY++   L G    +LPVP  NVINGG HAGN L  QEFMI+P+GA +F+EA+
Sbjct: 123 AAEKGVPLYRHIADLAGNEDVILPVPAFNVINGGSHAGNKLAMQEFMILPVGAENFKEAM 182

Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242
           R  +E Y  LK VI EKYGK+A NVGDEGGFAP + E  E L++L  AI +AGY   ++I
Sbjct: 183 RIGAEVYQNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKSAISKAGYT--DKI 240

Query: 243 ALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEED 295
            + +D A+SEFY+DGKY +  K         T ++L +LYK     YP+VSIEDPF + D
Sbjct: 241 VIGMDVAASEFYRDGKYDLDFKSPDDPSRYITPDQLSDLYKGFIKNYPVVSIEDPFDQHD 300

Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355
           W  +   T   G  +Q+VGDDL VTNP+R+ K +E  + N LLLKVNQIG++TE++ A  
Sbjct: 301 WAAWKKFTASAG--IQVVGDDLTVTNPRRITKAVEEKSCNCLLLKVNQIGSVTESLQACK 358

Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415
           +A   G+GV+VSHRSGETED  IADL V L  GQIKTGAP RS+R AKYNQ++RIEEEL 
Sbjct: 359 LAQTNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEELG 418

Query: 416 GVAVYAGKNFR 426
               +AG+NFR
Sbjct: 419 SKGRFAGRNFR 429


>pir||A37210 phosphopyruvate hydratase (EC 4.2.1.11) beta - rabbit
           Length = 433
           
 Score =  450 bits (1144), Expect = e-125
 Identities = 246/428 (57%), Positives = 304/428 (70%), Gaps = 17/428 (3%)

Query: 12  VIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRA 70
           + AREILDSRGNPTVEVD+HT     RAAVPSGASTG +EA+ELRDG K RY GKGV +A
Sbjct: 5   IFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKSRYLGKGVLKA 64

Query: 71  VENVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANA 128
           VE++NK + P L+   + V  Q ++D+ +IELDGTENKS  GANAIL VSLAV KA A  
Sbjct: 65  VEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAE 124

Query: 129 LELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWV 185
             +PLY++   L G +  VLPVP  NVINGG HAGN L  QEFMI+P+GA+SFREA+R  
Sbjct: 125 KGVPLYRHIADLAGNHDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFREAMRIG 184

Query: 186 SETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALA 245
           +E YH LK VI  KYGK+A NVGDEGGFAP + E  E L++L  AI+ AGY   +++ + 
Sbjct: 185 AEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYP--DKVVIG 242

Query: 246 LDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEEDWEG 298
           +D A+SEF++DGKY +  K         T ++L ELYK     YP+VSIEDPF + DW  
Sbjct: 243 MDVAASEFHRDGKYDLDFKSPDDPARHITGQKLGELYKSFIKNYPVVSIEDPFDQGDWGA 302

Query: 299 FVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAF 358
           +       G  +Q+VGDDL VTNPKR+ + +E  A N LLLKVNQIG++TE++ A  +A 
Sbjct: 303 WSRFLA--GVDIQVVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQ 360

Query: 359 RAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVA 418
             G+GV+VSHRSGETED  IADL V L  GQIKTGAP RS+R AKYNQL+RIEE L   A
Sbjct: 361 SNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKA 420

Query: 419 VYAGKNFR 426
           V+AG+ FR
Sbjct: 421 VFAGRKFR 428


>sp|P25704|ENOB_RABIT BETA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (SKELETAL MUSCLE
           ENOLASE)
           Length = 434
           
 Score =  450 bits (1144), Expect = e-125
 Identities = 246/428 (57%), Positives = 304/428 (70%), Gaps = 17/428 (3%)

Query: 12  VIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRA 70
           + AREILDSRGNPTVEVD+HT     RAAVPSGASTG +EA+ELRDG K RY GKGV +A
Sbjct: 6   IFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKSRYLGKGVLKA 65

Query: 71  VENVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANA 128
           VE++NK + P L+   + V  Q ++D+ +IELDGTENKS  GANAIL VSLAV KA A  
Sbjct: 66  VEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAE 125

Query: 129 LELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWV 185
             +PLY++   L G +  VLPVP  NVINGG HAGN L  QEFMI+P+GA+SFREA+R  
Sbjct: 126 KGVPLYRHIADLAGNHDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFREAMRIG 185

Query: 186 SETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALA 245
           +E YH LK VI  KYGK+A NVGDEGGFAP + E  E L++L  AI+ AGY   +++ + 
Sbjct: 186 AEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYP--DKVVIG 243

Query: 246 LDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEEDWEG 298
           +D A+SEF++DGKY +  K         T ++L ELYK     YP+VSIEDPF + DW  
Sbjct: 244 MDVAASEFHRDGKYDLDFKSPDDPARHITGQKLGELYKSFIKNYPVVSIEDPFDQGDWGA 303

Query: 299 FVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAF 358
           +       G  +Q+VGDDL VTNPKR+ + +E  A N LLLKVNQIG++TE++ A  +A 
Sbjct: 304 WSRFLA--GVDIQVVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQ 361

Query: 359 RAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVA 418
             G+GV+VSHRSGETED  IADL V L  GQIKTGAP RS+R AKYNQL+RIEE L   A
Sbjct: 362 SNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKA 421

Query: 419 VYAGKNFR 426
           V+AG+ FR
Sbjct: 422 VFAGRKFR 429


>gi|6679651 enolase 3, beta muscle [Mus musculus]
           >gi|119344|sp|P21550|ENOB_MOUSE BETA ENOLASE
           (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (SKELETAL MUSCLE
           ENOLASE) >gi|68306|pir||NOMSB phosphopyruvate hydratase
           (EC 4.2.1.11) beta - mouse >gi|50144|emb|CAA44540.1|
           (X62667) beta-enolase [Mus musculus]
           >gi|50847|emb|CAA40913.1| (X57747) enolase [Mus
           musculus] >gi|50849|emb|CAA43797.1| (X61600) enolase
           [Mus musculus]
           Length = 434
           
 Score =  449 bits (1143), Expect = e-125
 Identities = 246/428 (57%), Positives = 304/428 (70%), Gaps = 17/428 (3%)

Query: 12  VIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRA 70
           + AREILDSRGNPTVEVD+HT     RAAVPSGASTG +EA+ELRDG K RY GKGV +A
Sbjct: 6   IFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKARYLGKGVLKA 65

Query: 71  VENVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANA 128
           VE++NK + P L+   + V  Q ++D+ +IELDGTENKS  GANAIL VSLAV KA A  
Sbjct: 66  VEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAE 125

Query: 129 LELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWV 185
             +PLY++   L G    VLPVP  NVINGG HAGN L  QEFMI+P+GA+SF+EA+R  
Sbjct: 126 KGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEAMRIG 185

Query: 186 SETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALA 245
           +E YH LK VI  KYGK+A NVGDEGGFAP + E  E L++L  AI+ AGY   +++ + 
Sbjct: 186 AEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYP--DKVVIG 243

Query: 246 LDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEEDWEG 298
           +D A+SEFY++GKY +  K         + E+L ELYK     YP+VSIEDPF ++DW  
Sbjct: 244 MDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGELYKNFIQNYPVVSIEDPFDQDDWAT 303

Query: 299 FVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAF 358
           +       G  +QIVGDDL VTNPKR+ + +E  A N LLLKVNQIG++TE++ A  +A 
Sbjct: 304 WTSFLS--GVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQ 361

Query: 359 RAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVA 418
             G+GV+VSHRSGETED  IADL V L  GQIKTGAP RS+R AKYNQL+RIEE L   A
Sbjct: 362 SNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKA 421

Query: 419 VYAGKNFR 426
           V+AG+ FR
Sbjct: 422 VFAGRKFR 429


>emb|CAB96125.1| (AJ272111) enolase [Euglena gracilis]
           Length = 431
           
 Score =  449 bits (1143), Expect = e-125
 Identities = 241/431 (55%), Positives = 308/431 (70%), Gaps = 15/431 (3%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISM-GRAAVPSGASTGTHEAVELRDGGKR-YHGKG 66
           I  V AR+ILDSRGNPTVEVDV     + GR AVPSGASTG +EAVELRDG K  Y GKG
Sbjct: 4   IKTVKARQILDSRGNPTVEVDVILDNGLLGRGAVPSGASTGEYEAVELRDGDKAVYLGKG 63

Query: 67  VRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAA 126
           V ++VE VN I+AP+LVG+D   Q +ID L+ ELDGT NK  +GAN IL VS+AV +AAA
Sbjct: 64  VLKSVEAVNTIVAPKLVGLDPTEQLKIDNLMRELDGTPNKGKIGANGILGVSMAVCRAAA 123

Query: 127 NALELPLYQYLG---GVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIR 183
               +PLY+++G   G   + +PVP+ N+INGG HA N +DFQEFM+MP+GA +F E +R
Sbjct: 124 LVKGVPLYRHIGDLHGNKTFQMPVPMCNIINGGKHADNKIDFQEFMVMPVGAANFSEGLR 183

Query: 184 WVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIA 243
           W +E +H LK ++  K   +  +VGDEGGFAP +    E LD +I AI+ AG++PG++IA
Sbjct: 184 WCAEIFHHLKSIL--KKAGHVTSVGDEGGFAPNLDN-DEALDFVIAAIKAAGFEPGKQIA 240

Query: 244 LALDAASSEFYKDG-----KYIVSGKE--YTREELLELYKELTSTYPIVSIEDPFHEEDW 296
           +ALD ASSE + +G     KY  S  +  ++  E++E Y    + YPIVSIEDP  + DW
Sbjct: 241 IALDCASSELFDEGDRKGYKYWKSNPDRLFSAAEMIEKYAGWVAKYPIVSIEDPLDQNDW 300

Query: 297 EGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYM 356
           +G+V +T++LG K+QIVGDD FVTNP R KKGIE+ A N++L+KVNQIGT++E ++   M
Sbjct: 301 DGYVNMTKQLGGKIQIVGDDFFVTNPTRFKKGIELAACNSILIKVNQIGTVSETLECIKM 360

Query: 357 AFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEG 416
           A  AGY  V SHRSGETEDA IADLAV   AGQIKTG+ +R+DR AKYNQLIRIEEEL G
Sbjct: 361 AQAAGYTAVASHRSGETEDAFIADLAVGTAAGQIKTGSLSRTDRMAKYNQLIRIEEELGG 420

Query: 417 VAVYAGKNFRK 427
            A +     RK
Sbjct: 421 EAKWTTAMLRK 431


>gi|6978809 enolase 1, alpha [Rattus norvegicus] >gi|119341|sp|P04764|ENOA_RAT
           ALPHA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE)
           (NON-NEURAL ENOLASE) (NNE) >gi|92213|pir||A23126
           phosphopyruvate hydratase (EC 4.2.1.11) alpha - rat
           >gi|56107|emb|CAA26456.1| (X02610) alpha-alpha enolase
           (NNE) [Rattus norvegicus]
           Length = 434
           
 Score =  449 bits (1142), Expect = e-125
 Identities = 244/431 (56%), Positives = 307/431 (70%), Gaps = 17/431 (3%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67
           I+ + AREI DSRGNPTVEVD++T   + RAAVPSGASTG +EA+ELRD  K R+ GKGV
Sbjct: 3   ILKIHAREIFDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDNDKTRFMGKGV 62

Query: 68  RRAVENVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
            +AVE++NK IAP LV   ++V  Q +ID+L+IE+DGTENKS  GANAIL VSLAV KA 
Sbjct: 63  SKAVEHINKTIAPALVSKKLNVVEQEKIDQLMIEMDGTENKSKFGANAILGVSLAVCKAG 122

Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182
           A    +PLY++   L G     LPVP  NVINGG HAGN L  QEFMI+P+GA+SFREA+
Sbjct: 123 AVGKGVPLYRHIADLAGNPEVTLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFREAM 182

Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242
           R  +E YH LK VI EKYGK+A NVGDEGGFAP + E  E L++L  AI +AGY   +++
Sbjct: 183 RIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKSAIAKAGYT--DQV 240

Query: 243 ALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEED 295
            + +D A+SEFY+ GKY +  K         T ++L +LYK     YP+VSIEDPF ++D
Sbjct: 241 VIGMDVAASEFYRAGKYDLDFKSPDDASRYITPDQLADLYKSFIKDYPVVSIEDPFDQDD 300

Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355
           W+ +   T   G  +Q+VGDDL VTNPKR+ K     + N LLLKVNQIG++TE++ A  
Sbjct: 301 WDAWQKFTATAG--IQVVGDDLTVTNPKRIAKAAGEKSCNCLLLKVNQIGSVTESLQACK 358

Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415
           +A   G+GV+VSHRS ETED  IADL V L  GQIKTGAP RS+R AKYNQ++RIEEEL 
Sbjct: 359 LAQSNGWGVMVSHRSEETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEELG 418

Query: 416 GVAVYAGKNFR 426
             A +AG++FR
Sbjct: 419 SKAKFAGRSFR 429


>gb|AAF71925.1|AF260259_1 (AF260259) beta beta enolase [Oryctolagus cuniculus]
           Length = 434
           
 Score =  448 bits (1141), Expect = e-125
 Identities = 245/428 (57%), Positives = 305/428 (71%), Gaps = 17/428 (3%)

Query: 12  VIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRA 70
           + AREILDSRGNPTVEVD+HT     RAAVPSGASTG +EA+ELRDG K RY GKGV +A
Sbjct: 6   IFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKSRYLGKGVLKA 65

Query: 71  VENVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANA 128
           VE++NK + P L+   + V  Q ++D+ +IELDGTENKS  GANAIL VSLAV KA A  
Sbjct: 66  VEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAE 125

Query: 129 LELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWV 185
             +PLY++   L G +  VLPVP  NVINGG HAGN L  QEFMI+P+GA+SFREA+R  
Sbjct: 126 KGVPLYRHIADLAGNHDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFREAMRIG 185

Query: 186 SETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALA 245
           +E YH LK VI  KYGK+A NVGDEGGFAP + E  E L++L  AI+ AGY   +++ + 
Sbjct: 186 AEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYP--DKVVIG 243

Query: 246 LDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEEDWEG 298
           +D A+SEF+++GKY +  K         T ++L ELYK     YP+VSIEDPF++ DW  
Sbjct: 244 MDVAASEFHRNGKYDLDFKSPDDPARHITGQKLGELYKSFIKNYPVVSIEDPFNQGDWGA 303

Query: 299 FVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAF 358
           +       G  +Q+VGDDL VTNPKR+ + +E  A N LLLKVNQIG++TE++ A  +A 
Sbjct: 304 WSRFLA--GVDIQVVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQ 361

Query: 359 RAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVA 418
             G+GV+VSHRSGETED  IADL V L  GQIKTGAP RS+R AKYNQL+RIEE L   A
Sbjct: 362 SNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKA 421

Query: 419 VYAGKNFR 426
           V+AG+ FR
Sbjct: 422 VFAGRKFR 429


>pir||S43113 phosphopyruvate hydratase (EC 4.2.1.11) - fungus  (Cladosporium
           herbarum) >gi|467660|emb|CAA55070.1| (X78226)
           phosphopyruvate hydratase [Cladosporium herbarum]
           Length = 440
           
 Score =  446 bits (1135), Expect = e-124
 Identities = 246/435 (56%), Positives = 307/435 (70%), Gaps = 19/435 (4%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67
           I  + +R + DSRGNPTVEVD+ T   + RA VPS ASTG+HEA ELRDG K ++ GKGV
Sbjct: 3   ISKIHSRYVYDSRGNPTVEVDIVTETGLHRAIVPSVASTGSHEACELRDGDKSKWAGKGV 62

Query: 68  RRAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
            +AV NVN+IIAP L+   +DV+ Q  +D  L +LDGT NK+ +GANAIL VS+AVAKAA
Sbjct: 63  TKAVANVNEIIAPALIKENLDVKDQAAVDAFLNKLDGTTNKTKIGANAILGVSMAVAKAA 122

Query: 126 ANALELPLYQYLGGVNA----YVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREA 181
           A    +PLY ++  ++     +VLPVP  NV+NGG HAG  L FQEFMI+P GA SF EA
Sbjct: 123 AAEKRVPLYAHISDLSGTKKPFVLPVPFMNVVNGGSHAGGRLAFQEFMIVPSGAPSFTEA 182

Query: 182 IRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEE 241
           +R  +E Y  LK +  ++YG++A NVGDEGG AP ++   E LD++  AIEEAGY    +
Sbjct: 183 MRQGAEVYQKLKSLTKKRYGQSAGNVGDEGGVAPDIQTAEEALDLITDAIEEAGYTG--Q 240

Query: 242 IALALDAASSEFYK--DGKYIVSGKE--------YTREELLELYKELTSTYPIVSIEDPF 291
           I +A+D ASSEFYK  + KY +  K          T E+L + Y EL + YPIVSIEDPF
Sbjct: 241 IKIAMDVASSEFYKADEKKYDLDFKNPDSDKSKWITYEQLADQYNELAAKYPIVSIEDPF 300

Query: 292 HEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAM 351
            E+DWE +    +  G   QIVGDDL VTNP+ +KK IE  A NALLLKVNQIGT+TEA+
Sbjct: 301 AEDDWEAWSYFYKTSGSDFQIVGDDLTVTNPEFIKKAIETKACNALLLKVNQIGTITEAI 360

Query: 352 DAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIE 411
           +AA  +F AG+GV+VSHRSGETED TIAD+ V L AGQIKTGAPARS+R AK NQ++RIE
Sbjct: 361 NAAKDSFAAGWGVMVSHRSGETEDVTIADIVVGLRAGQIKTGAPARSERLAKLNQILRIE 420

Query: 412 EELEGVAVYAGKNFR 426
           EEL    +YAG NFR
Sbjct: 421 EELGDKRLYAGDNFR 435


>gb|AAF36733.1| (AC016662) putative enolase; 31277-33713 [Arabidopsis thaliana]
           Length = 477
           
 Score =  446 bits (1135), Expect = e-124
 Identities = 240/431 (55%), Positives = 316/431 (72%), Gaps = 19/431 (4%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGKR-YHGKGV 67
           +  V AR+I+DSRGNPTVEVD+ T   + R+AVPSGASTG +EA+ELRDG K  Y GKGV
Sbjct: 51  VKGVKARQIIDSRGNPTVEVDLITD-DLYRSAVPSGASTGIYEALELRDGDKSVYGGKGV 109

Query: 68  RRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAAN 127
            +A++N+N+++AP+L+G+DVR Q ++D L++ELDGT NKS LGANAIL VSL+V +A A 
Sbjct: 110 LQAIKNINELVAPKLIGVDVRNQADVDALMLELDGTPNKSKLGANAILGVSLSVCRAGAG 169

Query: 128 ALELPLYQYL---GGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRW 184
           A  +PLY+++    G    V+PVP  NVINGG HAGN L  QEFMI+P+GA SF EA + 
Sbjct: 170 AKGVPLYKHIQETSGTKELVMPVPAFNVINGGSHAGNSLAMQEFMILPVGATSFSEAFQM 229

Query: 185 VSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIAL 244
            SE YH LK +I  KYG++A NVGDEGGFAP +++  E L +LI AIE+AGY    +I +
Sbjct: 230 GSEVYHTLKGIIKTKYGQDACNVGDEGGFAPNVQDNREGLVLLIDAIEKAGYTG--KIKI 287

Query: 245 ALDAASSEFY-KDGKYIVSGKEY--------TREELLELYKELTSTYPIVSIEDPFHEED 295
            +D A+SEF+ KDG+Y ++ K+         + E L +LY+E    +PIVSIEDPF ++D
Sbjct: 288 GMDVAASEFFMKDGRYDLNFKKQPNDGAHVLSAESLADLYREFIKDFPIVSIEDPFDQDD 347

Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355
           W  +  +   +   +Q+VGDDL VTNPKR+ + I+  + NALLLKVNQIGT+TE++ AA 
Sbjct: 348 WSSWASLQSSVD--IQLVGDDLLVTNPKRIAEAIKKQSCNALLLKVNQIGTVTESIQAAL 405

Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415
            +  AG+GV+VSHRSGETED  IADL+V L +GQIKTGAP RS+R +KYNQL+RIEEEL 
Sbjct: 406 DSKAAGWGVMVSHRSGETEDNFIADLSVGLASGQIKTGAPCRSERLSKYNQLLRIEEELG 465

Query: 416 GVAVYAGKNFR 426
            V  YAG+ FR
Sbjct: 466 NVR-YAGEAFR 475


>sp|Q12560|ENO_ASPOR ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|2118302|pir||JC4542
           6beta-hydroxyhyoscyamine epoxidase (EC 1.14.11.14) -
           Aspergillus oryzae >gi|1217828|dbj|BAA09973.1| (D63941)
           enolase [Aspergillus oryzae] >gi|2665456|dbj|BAA23760.1|
           (D64113) enolase [Aspergillus oryzae]
           >gi|1586931|prf||2205241A enolase [Aspergillus oryzae]
           Length = 438
           
 Score =  445 bits (1132), Expect = e-124
 Identities = 250/435 (57%), Positives = 305/435 (69%), Gaps = 21/435 (4%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67
           I  + AR + DSRGNPTVEVDV T   + RA VPSGASTG HEA ELRDG K  + GKGV
Sbjct: 3   ITKIHARSVYDSRGNPTVEVDVVTETGLHRAIVPSGASTGQHEAHELRDGDKTHWGGKGV 62

Query: 68  RRAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
            +AVENVNK IAP ++   +DV+ Q ++D  L +LDG+ NKSNLGANAIL VSLA+AKA 
Sbjct: 63  LKAVENVNKTIAPAVIEENLDVKDQSKVDEFLKKLDGSANKSNLGANAILGVSLAIAKAG 122

Query: 126 ANALELPLYQYL----GGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREA 181
           A    +PLY ++    G    YVLPVP  NV+NGG HAG  L FQEFMI+P  A SF EA
Sbjct: 123 AAEKGVPLYAHISDLAGTKKPYVLPVPFQNVLNGGSHAGGRLAFQEFMIVPSAAPSFSEA 182

Query: 182 IRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEE 241
           +R  +E Y  LK +  +KYG++A NVGDEGG AP ++   E LD++ +AIE+AGY    +
Sbjct: 183 LRQGAEVYQKLKTLAKKKYGQSAGNVGDEGGVAPDIQTAEEALDLITEAIEQAGYTG--K 240

Query: 242 IALALDAASSEFYKDG--KYIV--------SGKEYTREELLELYKELTSTYPIVSIEDPF 291
           + +A+D ASSEFYK    KY +        S K  T E+L +LYK L S YPIVSIEDPF
Sbjct: 241 MKIAMDVASSEFYKADVKKYDLDFKNPDSDSSKWLTYEQLADLYKTLASKYPIVSIEDPF 300

Query: 292 HEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAM 351
            E+DWE +    +      QIVGDDL VTNP R+KK IE  A NALLLKVNQIGTLTE++
Sbjct: 301 AEDDWEAWSYFYKT--SDFQIVGDDLTVTNPLRIKKAIETKACNALLLKVNQIGTLTESI 358

Query: 352 DAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIE 411
            AA  ++   +GV+VSHRSGETED TIAD+AV L +GQIKTGAPARS+R AK NQ++RIE
Sbjct: 359 QAAKDSYADNWGVMVSHRSGETEDVTIADIAVGLRSGQIKTGAPARSERLAKLNQILRIE 418

Query: 412 EELEGVAVYAGKNFR 426
           EEL   A+YAG+ FR
Sbjct: 419 EELGNNAIYAGEKFR 433


>pir||T39737 enolase - fission yeast (Schizosaccharomyces pombe)
           >gi|4886570|emb|CAB43486.1| (AL050301) enolase
           [Schizosaccharomyces pombe] >gi|6579195|gb|AAA51399.2|
           (L37084) phosphopyruvate hydratase [Schizosaccharomyces
           pombe]
           Length = 439
           
 Score =  444 bits (1131), Expect = e-124
 Identities = 240/434 (55%), Positives = 307/434 (70%), Gaps = 19/434 (4%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67
           I  V AR+I DSRGNPTVEVD+ T   + RA VPSGASTG  EA+E+RDG K ++ GKGV
Sbjct: 3   IQKVFARQIYDSRGNPTVEVDLTTETGIHRAIVPSGASTGIWEALEMRDGDKTKWGGKGV 62

Query: 68  RRAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
            +AV NVN IIAP +V   +DV  Q+  D  L++LDGTENKS LGANAIL VS+A+ +A 
Sbjct: 63  LKAVGNVNNIIAPAVVKANLDVTDQKAADEFLLKLDGTENKSKLGANAILGVSMAICRAG 122

Query: 126 ANALELPLYQYL----GGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREA 181
           A   +LPL++Y+    G    YVLPVP  NV+NGG HAG DL FQEFMI+P GA SF EA
Sbjct: 123 AAQKKLPLWKYIAENFGTKGPYVLPVPSFNVLNGGSHAGGDLAFQEFMILPTGAPSFSEA 182

Query: 182 IRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEE 241
           +RW +ETYH LK +  ++YG +A NVGDEGG AP ++   E LD++++AI +AGY+   +
Sbjct: 183 MRWGAETYHTLKSIAKKRYGSSAGNVGDEGGIAPDLQTPQEALDLIVEAINKAGYEG--K 240

Query: 242 IALALDAASSEFYKDGKYIVSGK--------EYTREELLELYKELTSTYPIVSIEDPFHE 293
           I + LD ASSEFY DGKY +  K        + T ++L +LY EL+  YPIVSIEDPF +
Sbjct: 241 IKIGLDVASSEFYVDGKYDLDIKAAKPKPENKLTYQQLTDLYVELSKKYPIVSIEDPFDQ 300

Query: 294 EDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDA 353
           +DW  +  +  E     QIVGDDL VTN KRL+  I+   ANALLLKVNQIG++TE+++A
Sbjct: 301 DDWSAWTHMKAETD--FQIVGDDLTVTNVKRLRTAIDKKCANALLLKVNQIGSVTESLNA 358

Query: 354 AYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEE 413
             M++ AG+GV+VSHRSGET D  I+ L V + AGQ+K+GAP RS+R AKYN+L+RIEEE
Sbjct: 359 VRMSYEAGWGVMVSHRSGETADTFISHLTVGIGAGQLKSGAPCRSERLAKYNELLRIEEE 418

Query: 414 LEGVAVYAGKNFRK 427
           L    VYAG +  K
Sbjct: 419 LGSEGVYAGAHAGK 432


>sp|Q27877|ENO_SCHMA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|1002610|gb|AAC46884.1| (U33177) enolase
           [Schistosoma mansoni] >gi|1002616|gb|AAC46886.1|
           (U30175) enolase [Schistosoma mansoni]
           Length = 434
           
 Score =  443 bits (1126), Expect = e-123
 Identities = 247/432 (57%), Positives = 303/432 (69%), Gaps = 18/432 (4%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRD-GGKRYHGKGV 67
           I+ + AR+I DSRGNPTVEVD+ T   + RAAVPSGASTG HEA+ELRD   K Y  KGV
Sbjct: 3   ILTIHARQIFDSRGNPTVEVDLKTSKGLFRAAVPSGASTGVHEALELRDTNSKAYMKKGV 62

Query: 68  RRAVENVNKIIAPELVGMD--VRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
             AV NVNKIIAP L+  +  V  Q  ID+ +I+LDGTENK  LGANAIL VSLAV KA 
Sbjct: 63  LTAVSNVNKIIAPALINKNIPVTNQAAIDKYMIDLDGTENKEKLGANAILGVSLAVCKAG 122

Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182
           A    LPLY+Y   L G    ++PVP  NVINGG HAGN L  QEFMI+P GA+SF EA+
Sbjct: 123 AAEAGLPLYRYIARLAGHEDVIMPVPAFNVINGGSHAGNKLAMQEFMILPTGASSFTEAM 182

Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242
           +  +E YH LK VI  +YG +A NVGDEGGFAP +++  + L +L +AI+ AGY    EI
Sbjct: 183 QIGTEVYHNLKAVIKREYGLDACNVGDEGGFAPNIQDNMKGLQLLEEAIKIAGYTGKVEI 242

Query: 243 ALALDAASSEFYKDGKYIVSGKE--------YTREELLELYKELTSTYPIVSIEDPFHEE 294
            +  D A+SEF+K+GKY +  K          + + +  +YK++ S +PIVSIEDPF ++
Sbjct: 243 GM--DCAASEFHKNGKYDLDFKNPHSAESTWLSPDAMANMYKQMISKFPIVSIEDPFDQD 300

Query: 295 DWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAA 354
           DWE +  +T      +QIVGDDL VTNPKR+K+ I   A N LLLKVNQIG+LTE+++A 
Sbjct: 301 DWETWPKLTSSTN--IQIVGDDLTVTNPKRIKQAIASKACNCLLLKVNQIGSLTESIEAC 358

Query: 355 YMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEEL 414
            +A  +G+GV+VSHRSGETED  IADL V L  GQIKTGAP RSDR AKYNQL+RIEEEL
Sbjct: 359 KLAQDSGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSDRLAKYNQLLRIEEEL 418

Query: 415 EGVAVYAGKNFR 426
              A YAGKNFR
Sbjct: 419 GTAAKYAGKNFR 430


>gb|AAC78141.1| (AF100985) phosphopyruvate hydratase [Penaeus monodon]
           Length = 434
           
 Score =  442 bits (1125), Expect = e-123
 Identities = 241/435 (55%), Positives = 304/435 (69%), Gaps = 21/435 (4%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67
           I  V AR I DSRGNPTVEVD++T   + RAAVPSGASTG HEA+E+RDG K +YHGK V
Sbjct: 3   ITKVFARTIFDSRGNPTVEVDLYTHKGLFRAAVPSGASTGVHEALEMRDGDKSKYHGKSV 62

Query: 68  RRAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
            +AV NVN IIAPE++  G+ V  Q+E D  + +LDGTENKS LGANAIL VSLA+ KA 
Sbjct: 63  FKAVNNVNSIIAPEIIKSGLKVTQQKECDDFMCKLDGTENKSRLGANAILGVSLAICKAG 122

Query: 126 ANALELPLYQYLGGVNAY---VLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182
           A  L +PLY+++  +  Y   +LPVP  NVINGG HAGN L  QEFMI+P GA SF EA+
Sbjct: 123 AAELGIPLYRHIANLANYSDVILPVPAFNVINGGSHAGNKLAMQEFMILPTGATSFTEAM 182

Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242
           R  SE YH LK VI  ++G +A  VGDEGGFAP +    + L ++ ++IE+AGY    +I
Sbjct: 183 RMGSEVYHHLKAVIKGRFGLDATAVGDEGGFAPNILNNKDALTLIQESIEKAGYTG--KI 240

Query: 243 ALALDAASSEFYKDGKYIVS----------GKEYTREELLELYKELTSTYPIVSIEDPFH 292
            + +D A+SEFYK G+ I             ++ T ++L ++Y E    +PIVSIEDPF 
Sbjct: 241 EIGMDVAASEFYK-GENIYDLDFKTANNDGSQKITGDQLRDMYMEFCKEFPIVSIEDPFD 299

Query: 293 EEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMD 352
           ++DWE +  +T      +QIVGDDL VTNPKR+   +E  A N LLLKVNQIG++TE++D
Sbjct: 300 QDDWENWTKMTS--ATNIQIVGDDLTVTNPKRIATAVEKKACNCLLLKVNQIGSVTESID 357

Query: 353 AAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEE 412
           A  +A + G+G +VSHRSGETED  IADL V L  GQIKTGAP RS+R AKYNQ++RIEE
Sbjct: 358 AHLLAKKNGWGTMVSHRSGETEDCFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEE 417

Query: 413 ELEGVAVYAGKNFRK 427
           EL G A +AGK FRK
Sbjct: 418 ELGGNAKFAGKKFRK 432


>sp|Q9ZMS6|ENO_HELPJ ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|7436886|pir||H71967 enolase -
           Helicobacter pylori (strain J99)
           >gi|4154655|gb|AAD05723.1| (AE001453) ENOLASE
           [Helicobacter pylori J99]
           Length = 426
           
 Score =  441 bits (1123), Expect = e-123
 Identities = 232/419 (55%), Positives = 299/419 (70%), Gaps = 8/419 (1%)

Query: 14  AREILDSRGNPTVEVDVH-TPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRAV 71
           A E++DSRGNPT++  V  +  +   A VPSGASTG  EA+ELRD  K R+ GKGV RA 
Sbjct: 9   ALEVMDSRGNPTIQASVILSDNTKASAIVPSGASTGKREALELRDNDKTRFLGKGVLRAC 68

Query: 72  ENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANALEL 131
           ENVN +I   L+G++   Q  +D  L  LDGT N +NLGANA+L VS+A+A+A+A AL L
Sbjct: 69  ENVNSVIKHHLIGLEATNQAFVDERLRALDGTPNYANLGANAVLGVSMALARASAKALNL 128

Query: 132 PLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVSETYHV 191
           PLY+YLGG NA  LPVP+ N+INGG HA N +DFQE+MIMP+G  SF+EA+R  +E YH 
Sbjct: 129 PLYRYLGGANALTLPVPMLNIINGGTHANNSIDFQEYMIMPLGFESFKEALRASAEVYHT 188

Query: 192 LKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALALDAASS 251
           LKK++ EK      +VGDEGGFAP      EPL+++ +AIE+AGYK GEEIALALD ASS
Sbjct: 189 LKKLLDEK--NQLTSVGDEGGFAPNFNNNVEPLEIISQAIEKAGYKLGEEIALALDVASS 246

Query: 252 EFYKDG-KYIVSG--KEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMITRELGK 308
           E   +   Y + G  K     EL+  YKEL + YPIVSIED   E+DWEG+  +++ELG+
Sbjct: 247 ELVDEHFNYHLKGENKILDSHELVAYYKELVAKYPIVSIEDGLSEDDWEGWAFLSKELGR 306

Query: 309 KVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYGVVVSH 368
           ++Q+VGDDLFVTN   L+KGIE   ANA+L+K NQIGT++E ++   +A    Y  V+SH
Sbjct: 307 QIQLVGDDLFVTNASILQKGIEKNVANAILIKPNQIGTISETLETIRLAKHHAYQCVISH 366

Query: 369 RSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAGKNFRK 427
           RSGE+ED+ IAD AVALN G+IKTG+ ARS+R AKYN+L+ IE EL+G  +Y GK   K
Sbjct: 367 RSGESEDSFIADFAVALNTGEIKTGSTARSERIAKYNRLLEIEHELKG-GIYIGKELFK 424


>gb|AAD33073.1|AF149256_1 (AF149256) alpha enolase [Bos taurus]
           Length = 434
           
 Score =  441 bits (1123), Expect = e-123
 Identities = 240/431 (55%), Positives = 300/431 (68%), Gaps = 17/431 (3%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67
           I+ V AREI DSRGNPTVEVD+ T   + RAAVPSGASTG +EA+ELRD  K RY GKGV
Sbjct: 3   ILKVHAREIFDSRGNPTVEVDLFTAKGLFRAAVPSGASTGIYEALELRDNDKTRYMGKGV 62

Query: 68  RRAVENVNKIIAPELVGM--DVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
            +AVE++NK IAP LV    +V  Q +ID+L+IE+DGTE KS  GANAIL VSLAV KA 
Sbjct: 63  SKAVEHINKTIAPALVSKKSNVVEQEKIDKLMIEMDGTEKKSKFGANAILGVSLAVCKAG 122

Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182
           A    +PLY++   L G    +LPVP  NVINGG HAGN L  QEFMI+P+GA +FREA+
Sbjct: 123 AVEKGVPLYRHIADLAGNAEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGAENFREAM 182

Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242
           R  +E YH LK VI EKYGK+A NVGDEGGFAP + E  E L++L  AI +AGY   +++
Sbjct: 183 RIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKNAIGKAGYS--DKV 240

Query: 243 ALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEED 295
            + +D A+SEFY+ GKY +  K         T +EL  LYK     YP+VSIEDPF ++D
Sbjct: 241 VIGMDVAASEFYRSGKYDLDFKSPDDPSRYITPDELANLYKSFIRDYPVVSIEDPFDQDD 300

Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355
           WE +   T   G  +Q+VGDDL VT PK + KG+   + N LLLKVNQ G++TE++    
Sbjct: 301 WEAWQKFTASAG--IQVVGDDLTVTTPKTIAKGVNEKSCNCLLLKVNQNGSVTESLQGCK 358

Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415
           +A   G+GV+VSHRSGET+D  IA+L V L  GQIK G P R++R AKYNQ++RIEEEL 
Sbjct: 359 LAHANGWGVMVSHRSGETDDTFIAELVVGLCTGQIKNGPPCRTERLAKYNQILRIEEELG 418

Query: 416 GVAVYAGKNFR 426
             A +AG+NFR
Sbjct: 419 SKAKFAGRNFR 429


>gb|AAF73201.1|AF152348_1 (AF152348) enolase [Trypanosoma brucei brucei]
           Length = 429
           
 Score =  441 bits (1123), Expect = e-123
 Identities = 238/417 (57%), Positives = 299/417 (71%), Gaps = 13/417 (3%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67
           I  V  RE+LDSRGNPTVEV+V T   + R+AVPSGASTG +EA ELRDG K RY GKG 
Sbjct: 3   IQKVHGREVLDSRGNPTVEVEVTTERGVFRSAVPSGASTGVYEACELRDGDKKRYVGKGC 62

Query: 68  RRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAAN 127
            +AV+NVN++I P L+G D   Q E+D L++ LDGT NK  LGANAIL  S+A++KAAA 
Sbjct: 63  LQAVKNVNEVIGPALIGRDELKQEELDTLMLRLDGTPNKGKLGANAILGCSMAISKAAAA 122

Query: 128 ALELPLYQYLG---GVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRW 184
           A  +PLY+YL    G     LPVP  NVINGG HAGN L FQEFMI P+ A SF EA+R 
Sbjct: 123 AKGVPLYRYLASLAGTKELRLPVPCFNVINGGKHAGNALPFQEFMIAPVKATSFSEALRM 182

Query: 185 VSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIAL 244
            SE YH L+ +I +KYG++AVNVGDEGGFAPP+K++ EPL +L++AIEEAG++   + A+
Sbjct: 183 GSEVYHSLRGIIKKKYGQDAVNVGDEGGFAPPIKDINEPLPILMEAIEEAGHRG--KFAI 240

Query: 245 ALDAASSEFYKDGK--YIVSGKE-----YTREELLELYKELTSTYPIVSIEDPFHEEDWE 297
            +D A+SE Y + K  Y ++ K       T E+L E Y +    YPIVSIEDP+ ++D+ 
Sbjct: 241 CMDCAASETYDEKKQQYNLTFKSPEPTWVTAEQLRETYCKWAHDYPIVSIEDPYDQDDFA 300

Query: 298 GFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMA 357
           GF  IT  L  K QIVGDDL VTN +R+K  IE  A N+LLLK+NQIGT++EA+ ++ + 
Sbjct: 301 GFAGITEALKGKTQIVGDDLTVTNTERIKMAIEKKACNSLLLKINQIGTISEAIASSKLC 360

Query: 358 FRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEEL 414
              G+ V+VSHRSGETED  IADL VAL +GQIKTGAP R +R AK NQL+RIEEEL
Sbjct: 361 MENGWSVMVSHRSGETEDTYIADLVVALGSGQIKTGAPCRGERTAKLNQLLRIEEEL 417


>pir||E82076 enolase VC2447 [imported] - Vibrio cholerae (group O1 strain
           N16961) >gi|9657023|gb|AAF95589.1| (AE004314) enolase
           [Vibrio cholerae]
           Length = 433
           
 Score =  441 bits (1123), Expect = e-123
 Identities = 242/425 (56%), Positives = 303/425 (70%), Gaps = 12/425 (2%)

Query: 8   EIVAVIAREILDSRGNPTVEVDVHTPIS-MGRAAVPSGASTGTHEAVELRDGGK-RYHGK 65
           +IV V+ REI+DSRGNPTVE +VH     +G AA PSGASTG+ EA+ELRDG K R+ GK
Sbjct: 3   KIVKVLGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGK 62

Query: 66  GVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
           GV +A+  VN  IA  LVG D + Q  ID+++I+LDGTENKSN GANAILAVSLA AKAA
Sbjct: 63  GVLKALAAVNGPIADALVGKDAKDQATIDQIMIDLDGTENKSNFGANAILAVSLANAKAA 122

Query: 126 ANALELPLYQYLGGVNA----YVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREA 181
           A A  +PLY+++  +N     + +P+P+ N+INGG HA N++D QEFMI P+GA + +EA
Sbjct: 123 AAAKGMPLYEHIAELNGTPGVFSMPLPMMNIINGGEHADNNVDIQEFMIQPVGAKTLKEA 182

Query: 182 IRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEE 241
           +R  +E +H L KV+  K G N   VGDEGGFAP +K   E L+V+ +A+  AGYK G +
Sbjct: 183 VRMGAEVFHNLAKVLKSK-GYNTA-VGDEGGFAPNLKSNAEALEVIAEAVAAAGYKLGTD 240

Query: 242 IALALDAASSEFY----KDGKYIVSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWE 297
           I LA+D A+SEFY    K+      G+ +T     +  +ELT  +PIVSIED   E DWE
Sbjct: 241 ITLAMDCAASEFYDAEKKEYNLKGEGRIFTSNGFSDFLEELTEKFPIVSIEDGLDESDWE 300

Query: 298 GFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMA 357
           GF   T +LGKK+QIVGDDLFVTN K LK+GI+ G AN++L+K NQIG+LTE + A  MA
Sbjct: 301 GFAYQTEKLGKKIQIVGDDLFVTNTKILKRGIDNGIANSILIKFNQIGSLTETLAAIKMA 360

Query: 358 FRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGV 417
             AGY  V+SHRSGETEDATIADLAV   AGQIKTG+ +RSDR AKYNQLIRIEE L   
Sbjct: 361 KDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGSR 420

Query: 418 AVYAG 422
           A + G
Sbjct: 421 APFNG 425


>sp|P43806|ENO_HAEIN ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|1074058|pir||E64103 phosphopyruvate
           hydratase (EC 4.2.1.11) - Haemophilus influenzae (strain
           Rd KW20) >gi|1573953|gb|AAC22590.1| (U32775) enolase
           (eno) [Haemophilus influenzae Rd]
           Length = 436
           
 Score =  441 bits (1122), Expect = e-123
 Identities = 244/418 (58%), Positives = 300/418 (71%), Gaps = 12/418 (2%)

Query: 8   EIVAVIAREILDSRGNPTVEVDVHTPIS-MGRAAVPSGASTGTHEAVELRDGGK-RYHGK 65
           +IV VI REI+DSRGNPTVE +VH     +G AA PSGASTG+ EA+ELRDG K R+ GK
Sbjct: 3   KIVKVIGREIIDSRGNPTVEAEVHLXGGFVGLAAAPSGASTGSREALELRDGDKSRFLGK 62

Query: 66  GVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
           GV +AV  VN  IA  +VG D   Q EID+++I+LDGTENKSN GANAILAVSLA AKAA
Sbjct: 63  GVLKAVAAVNNEIAQAIVGKDATNQAEIDQIMIDLDGTENKSNFGANAILAVSLANAKAA 122

Query: 126 ANALELPLYQYLGGVNA----YVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREA 181
           A +  LPLY Y+  +N     Y +P+P+ N+INGG HA N++D QEFMI P+GA + REA
Sbjct: 123 AASKGLPLYAYIAELNGTAGVYSMPLPMMNIINGGEHADNNVDIQEFMIQPVGAKTLREA 182

Query: 182 IRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEE 241
           +R  +E +H L KV+  K    AV  GDEGGFAP +    + L  + +A+E+AGY  G++
Sbjct: 183 LRIGAEVFHNLAKVLKAKGMSTAV--GDEGGFAPNLASNADALACIKEAVEKAGYVLGKD 240

Query: 242 IALALDAASSEFY--KDGKYIVSG--KEYTREELLELYKELTSTYPIVSIEDPFHEEDWE 297
           + LA+D ASSEFY  ++G Y + G  K +T +E     +EL   YPIVSIED   E DWE
Sbjct: 241 VTLAMDCASSEFYNKENGMYEMKGEGKSFTSQEFTHYLEELCKEYPIVSIEDGQDESDWE 300

Query: 298 GFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMA 357
           GF   T+ LG +VQ+VGDDLFVTN K LK+GIE G AN++L+K NQIG+LTE + A  MA
Sbjct: 301 GFAYQTKVLGDRVQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMA 360

Query: 358 FRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415
             AGY  V+SHRSGETEDATIADLAV   AGQIKTG+ +RSDR AKYNQLIRIEE LE
Sbjct: 361 KDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRIAKYNQLIRIEEALE 418


>sp|P42448|ENO_CAMJE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|11268976|pir||E81264 phosphopyruvate
           hydratase (EC 4.2.1.11) Cj1672c [imported] -
           Campylobacter jejuni (strain NCTC 11168)
           >gi|6969088|emb|CAB73659.1| (AL139079) enolase
           [Campylobacter jejuni]
           Length = 414
           
 Score =  441 bits (1122), Expect = e-123
 Identities = 231/403 (57%), Positives = 296/403 (73%), Gaps = 5/403 (1%)

Query: 12  VIAREILDSRGNPTVEVDVH-TPISMGRAAVPSGASTGTHEAVELRDGGKRYHGKGVRRA 70
           V A E+LDSRGNPTV+ +V  +  S+G A VPSGASTG+ EA+ELRD  +R+ GKGV +A
Sbjct: 7   VRAYEVLDSRGNPTVKAEVTLSDGSVGAAIVPSGASTGSKEALELRDNDERFGGKGVLKA 66

Query: 71  VENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANALE 130
           V NVN+ IA E++G+D   Q ++D  L ELDGT N SNLGANA L VS+A A+AAA AL 
Sbjct: 67  VANVNETIADEILGLDAFNQTQLDDTLRELDGTNNYSNLGANATLGVSMATARAAAAALG 126

Query: 131 LPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVSETYH 190
           +PLY+YLGG NA +LPVP+ N+INGG HA N++DFQEFMIMP G  SF+EA+R V E Y 
Sbjct: 127 MPLYRYLGGANASILPVPMCNIINGGAHANNNVDFQEFMIMPFGFTSFKEALRSVCEIYA 186

Query: 191 VLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALALDAAS 250
           +LKK +A      A  +GDEGGFAP +   TEP+D+L+  I++AGY+    + +ALD AS
Sbjct: 187 ILKKELANSGHSTA--LGDEGGFAPNLANNTEPIDLLMTCIKKAGYE--NRVKIALDVAS 242

Query: 251 SEFYKDGKYIVSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMITRELGKKV 310
           +EF+KDGKY + GK ++ E L+E Y EL + YPI SIED   E D+EG++ +T +LG K+
Sbjct: 243 TEFFKDGKYHMEGKAFSSEALIERYVELCAKYPICSIEDGLAENDFEGWIKLTEKLGNKI 302

Query: 311 QIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYGVVVSHRS 370
           Q+VGDDLFVTN   L++GI    ANA+L+K NQIGT+T+ M    +A R  Y  V+SHRS
Sbjct: 303 QLVGDDLFVTNEDILREGIIKKMANAVLIKPNQIGTITQTMRTVRLAQRNNYKCVMSHRS 362

Query: 371 GETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEE 413
           GE+EDA IAD AVALN GQIKTGA AR +R AKYN+L+ IE E
Sbjct: 363 GESEDAFIADFAVALNTGQIKTGALARGERTAKYNRLLEIEFE 405


>pir||F82700 enolase XF1291 [imported] - Xylella fastidiosa (strain 9a5c)
           >gi|9106280|gb|AAF84100.1|AE003962_10 (AE003962) enolase
           [Xylella fastidiosa]
           Length = 461
           
 Score =  439 bits (1118), Expect = e-122
 Identities = 238/422 (56%), Positives = 298/422 (70%), Gaps = 8/422 (1%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISM-GRAAVPSGASTGTHEAVELRDGGK-RYHGKG 66
           I  + AREILDSRGNPT+E +V    ++ GRAAVPSGASTGT EAVELRDG K RY GKG
Sbjct: 35  IAKIYAREILDSRGNPTLEAEVTLENAVCGRAAVPSGASTGTKEAVELRDGDKTRYLGKG 94

Query: 67  VRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAA 126
           VR AV+NVN +IA  LVG D   Q  +D  LI LDGTENK  LGANA+L VSLA A A A
Sbjct: 95  VRAAVDNVNGVIAAALVGFDGADQTGLDHRLINLDGTENKGRLGANALLGVSLATAHAVA 154

Query: 127 NALELPLYQYLG--GVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRW 184
            A + PL+ YL   G +   LPVP+ N+INGG HA N++DFQEFM++P+G  SF EA+R 
Sbjct: 155 AARKQPLWMYLSTLGESKVSLPVPMMNIINGGAHADNNVDFQEFMVLPVGFASFSEALRA 214

Query: 185 VSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIAL 244
            +E +H LK V+  +    AV  GDEGGFAP ++   E LD +++AI  AGY  GE++ L
Sbjct: 215 GTEIFHALKSVLKGQGLSTAV--GDEGGFAPDLRSNVEALDAILEAIGRAGYIAGEDVLL 272

Query: 245 ALDAASSEFYKDGKYIVSG--KEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMI 302
            LD ASSEF  +GKY + G  K  T E+ ++   +  + YPI+SIED   E+DW G+  +
Sbjct: 273 GLDVASSEFRDNGKYNLVGENKRLTSEQFVDFLDDWVTQYPIISIEDGLAEDDWAGWKQL 332

Query: 303 TRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGY 362
           T  +G KVQ+VGDDLFVTNPK  ++GI  G ANA+L+K+NQIGTLTE +++  MA RA Y
Sbjct: 333 TERIGHKVQLVGDDLFVTNPKVFQEGITSGIANAILIKLNQIGTLTETLESIAMAHRAQY 392

Query: 363 GVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAG 422
             +VSHRSGETED +IAD+AVA  A QIKTG+  RSDR AKYNQL+RIE+ L   A YAG
Sbjct: 393 AAIVSHRSGETEDTSIADIAVATTATQIKTGSLCRSDRVAKYNQLLRIEQALGVGARYAG 452

Query: 423 KN 424
           ++
Sbjct: 453 RD 454


>pdb|1PDZ|   Mol_id: 1; Molecule: Enolase; Chain: Null; Synonym:
           2-Phospho-D-Glycerate Dehydratase; Ec: 4.2.1.11;
           Heterogen: Phosphoglycolate; Heterogen: Mn 2+
           >gi|1311142|pdb|1PDY|  Mol_id: 1; Molecule: Enolase;
           Chain: Null; Synonym: 2-Phospho-D-Glycerate Dehydratase;
           Ec: 4.2.1.11
           Length = 434
           
 Score =  439 bits (1117), Expect = e-122
 Identities = 239/438 (54%), Positives = 303/438 (68%), Gaps = 29/438 (6%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67
           I  V AR I DSRGNPTVEVD++T   + RAAVPSGASTG HEA+E+RDG K +YHGK V
Sbjct: 3   ITKVFARTIFDSRGNPTVEVDLYTSKGLFRAAVPSGASTGVHEALEMRDGDKSKYHGKSV 62

Query: 68  RRAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
             AV+NVN +I PE++  G+ V  Q+E D  + +LDGTENKS+LGANAIL VSLA+ KA 
Sbjct: 63  FNAVKNVNDVIVPEIIKSGLKVTQQKECDEFMCKLDGTENKSSLGANAILGVSLAICKAG 122

Query: 126 ANALELPLYQYLGGVNAY---VLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182
           A  L +PLY+++  +  Y   +LPVP  NVINGG HAGN L  QEFMI+P GA SF EA+
Sbjct: 123 AAELGIPLYRHIANLANYDEVILPVPAFNVINGGSHAGNKLAMQEFMILPTGATSFTEAM 182

Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242
           R  +E YH LK VI  ++G +A  VGDEGGFAP +    + LD++ +AI++AGY    +I
Sbjct: 183 RMGTEVYHHLKAVIKARFGLDATAVGDEGGFAPNILNNKDALDLIQEAIKKAGYTG--KI 240

Query: 243 ALALDAASSEFYK--------------DGKYIVSGKEYTREELLELYKELTSTYPIVSIE 288
            + +D A+SEFYK              DG   +SG     ++L ++Y E    +PIVSIE
Sbjct: 241 EIGMDVAASEFYKQNNIYDLDFKTANNDGSQKISG-----DQLRDMYMEFCKDFPIVSIE 295

Query: 289 DPFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLT 348
           DPF ++DWE +  +T   G  +QIVGDDL VTNPKR+   +E  A   LLLKVNQIG++T
Sbjct: 296 DPFDQDDWETWSKMTS--GTTIQIVGDDLTVTNPKRITTAVEKKACKCLLLKVNQIGSVT 353

Query: 349 EAMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLI 408
           E++DA  +A + G+G +VSHRSGETED  IADL V L  GQIKTGAP RS+R AKYNQ++
Sbjct: 354 ESIDAHLLAKKNGWGTMVSHRSGETEDCFIADLVVGLCTGQIKTGAPCRSERLAKYNQIL 413

Query: 409 RIEEELEGVAVYAGKNFR 426
           RIEEEL   A +AGKNFR
Sbjct: 414 RIEEELGSGAKFAGKNFR 431


>sp|P56252|ENO_HOMGA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE)
           Length = 433
           
 Score =  439 bits (1117), Expect = e-122
 Identities = 239/438 (54%), Positives = 303/438 (68%), Gaps = 29/438 (6%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67
           I  V AR I DSRGNPTVEVD++T   + RAAVPSGASTG HEA+E+RDG K +YHGK V
Sbjct: 2   ITKVFARTIFDSRGNPTVEVDLYTSKGLFRAAVPSGASTGVHEALEMRDGDKSKYHGKSV 61

Query: 68  RRAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
             AV+NVN +I PE++  G+ V  Q+E D  + +LDGTENKS+LGANAIL VSLA+ KA 
Sbjct: 62  FNAVKNVNDVIVPEIIKSGLKVTQQKECDEFMCKLDGTENKSSLGANAILGVSLAICKAG 121

Query: 126 ANALELPLYQYLGGVNAY---VLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182
           A  L +PLY+++  +  Y   +LPVP  NVINGG HAGN L  QEFMI+P GA SF EA+
Sbjct: 122 AAELGIPLYRHIANLANYDEVILPVPAFNVINGGSHAGNKLAMQEFMILPTGATSFTEAM 181

Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242
           R  +E YH LK VI  ++G +A  VGDEGGFAP +    + LD++ +AI++AGY    +I
Sbjct: 182 RMGTEVYHHLKAVIKARFGLDATAVGDEGGFAPNILNNKDALDLIQEAIKKAGYTG--KI 239

Query: 243 ALALDAASSEFYK--------------DGKYIVSGKEYTREELLELYKELTSTYPIVSIE 288
            + +D A+SEFYK              DG   +SG     ++L ++Y E    +PIVSIE
Sbjct: 240 EIGMDVAASEFYKQNNIYDLDFKTANNDGSQKISG-----DQLRDMYMEFCKDFPIVSIE 294

Query: 289 DPFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLT 348
           DPF ++DWE +  +T   G  +QIVGDDL VTNPKR+   +E  A   LLLKVNQIG++T
Sbjct: 295 DPFDQDDWETWSKMTS--GTTIQIVGDDLTVTNPKRITTAVEKKACKCLLLKVNQIGSVT 352

Query: 349 EAMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLI 408
           E++DA  +A + G+G +VSHRSGETED  IADL V L  GQIKTGAP RS+R AKYNQ++
Sbjct: 353 ESIDAHLLAKKNGWGTMVSHRSGETEDCFIADLVVGLCTGQIKTGAPCRSERLAKYNQIL 412

Query: 409 RIEEELEGVAVYAGKNFR 426
           RIEEEL   A +AGKNFR
Sbjct: 413 RIEEELGSGAKFAGKNFR 430


>sp|P48285|ENO_HELPY ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|7436877|pir||S58684 phosphopyruvate
           hydratase (EC 4.2.1.11) - Helicobacter pylori (strains
           26695 and others) >gi|2313236|gb|AAD07219.1| (AE000536)
           enolase (eno) [Helicobacter pylori 26695]
           Length = 426
           
 Score =  439 bits (1116), Expect = e-122
 Identities = 234/420 (55%), Positives = 301/420 (70%), Gaps = 10/420 (2%)

Query: 14  AREILDSRGNPTVEVDVH-TPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRAV 71
           A E++DSRGNPT++  V  +  +   A VPSGASTG  EA+ELRD  K R+ GKGV RA 
Sbjct: 9   ALEVMDSRGNPTIQASVVLSDNTKASAIVPSGASTGKREALELRDNDKTRFLGKGVLRAC 68

Query: 72  ENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANALEL 131
           ENVN +I   L+G++   Q  +D  L  LDGT N +NLGANA+L VS+A+A+A+A AL L
Sbjct: 69  ENVNSVIKHHLIGLEAINQAFVDERLRALDGTPNYANLGANAVLGVSMALARASAKALNL 128

Query: 132 PLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVSETYHV 191
           PLY+YLGG NA  LPVP+ N+INGG HA N +DFQE+MIMP+G  SF+EA+R  +E YH 
Sbjct: 129 PLYRYLGGANALTLPVPMLNIINGGTHANNSIDFQEYMIMPLGFESFKEALRASAEVYHT 188

Query: 192 LKKVIAEKYGKNAV-NVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALALDAAS 250
           LKK++    GKN + +VGDEGGFAP      EPL+V+ +AIE+AGYK GEEIALALD AS
Sbjct: 189 LKKLLD---GKNQLTSVGDEGGFAPNFSNNVEPLEVISQAIEKAGYKLGEEIALALDVAS 245

Query: 251 SEFYKDG-KYIVSG--KEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMITRELG 307
           SE   +   Y + G  K     EL+  YKEL + YPIVSIED   E+DWEG+  +++ELG
Sbjct: 246 SELVDENFNYHLKGENKILDSHELVAYYKELVAKYPIVSIEDGLSEDDWEGWAFLSKELG 305

Query: 308 KKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYGVVVS 367
           +++Q+VGDDLFVTN   L+KGIE   ANA+L+K NQIGT++E ++   +A    Y  V+S
Sbjct: 306 RQIQLVGDDLFVTNASLLQKGIEKNIANAVLIKPNQIGTISETLETIRLAKHHAYQCVMS 365

Query: 368 HRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAGKNFRK 427
           HRSGE+ED+ IAD AVALN G+IKTG+ ARS+R AKYN+L+ IE EL+G  +Y GK   K
Sbjct: 366 HRSGESEDSFIADFAVALNTGEIKTGSTARSERIAKYNRLLEIEHELKG-GIYIGKELFK 424


>emb|CAB94039.1| (AL358652) enolase [Leishmania major]
           Length = 429
           
 Score =  437 bits (1111), Expect = e-121
 Identities = 236/420 (56%), Positives = 297/420 (70%), Gaps = 13/420 (3%)

Query: 12  VIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRA 70
           V ARE+LDSRGNPTVEV++ T   + R+AVPSGASTG HEA ELRDG K RY G G  +A
Sbjct: 6   VYAREVLDSRGNPTVEVELMTEAGVFRSAVPSGASTGVHEACELRDGDKARYCGAGCTQA 65

Query: 71  VENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANALE 130
           V+NVN+I+AP LVG +   Q  +D+++ ELDGT+NKS LGANAIL  S+A++KAAA    
Sbjct: 66  VKNVNEILAPALVGKEESDQAGLDKMMCELDGTKNKSKLGANAILGCSMAISKAAAAKAG 125

Query: 131 LPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVSE 187
           +PLY+Y   L G     LPVP  NVINGG HAGN L FQEFMI P  A SFREA+R  SE
Sbjct: 126 VPLYRYIASLAGTKDIRLPVPCFNVINGGKHAGNILPFQEFMIAPTKATSFREALRMGSE 185

Query: 188 TYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALALD 247
            YH LK +I  KYG++AVNVGDEGGFAPP+K + EPL +L++AIE+AG+K   + A+ +D
Sbjct: 186 VYHALKVIIKSKYGQDAVNVGDEGGFAPPIKHIDEPLPILMEAIEKAGHKG--KFAICMD 243

Query: 248 AASSEFYKDGK--YIVSGKE-----YTREELLELYKELTSTYPIVSIEDPFHEEDWEGFV 300
            A+SE Y   +  Y ++ K       +  EL   Y+   + YP+VSIEDPF E++++ F 
Sbjct: 244 CAASEAYDAERKMYNLTFKNPEPTYVSAAELQATYERWVAEYPLVSIEDPFAEDNFDEFS 303

Query: 301 MITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRA 360
            IT+ L  K QIVGDDL VTN KR+   IE  A N+LLLK+NQIGT++E++ AA +    
Sbjct: 304 AITKALAGKAQIVGDDLTVTNVKRVTMAIEKSACNSLLLKINQIGTISESIAAAKLCMEN 363

Query: 361 GYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVY 420
           G+ V+VSHRSGETED  IADL+V L  GQIKTGAP R +R AK NQL+RIEEE+   A Y
Sbjct: 364 GWSVMVSHRSGETEDTYIADLSVGLGTGQIKTGAPCRGERTAKLNQLLRIEEEIGSTATY 423


>emb|CAB96126.1| (AJ272112) chloroplast enolase [Euglena gracilis]
           Length = 485
           
 Score =  436 bits (1110), Expect = e-121
 Identities = 231/429 (53%), Positives = 304/429 (70%), Gaps = 16/429 (3%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISM-GRAAVPSGASTGTHEAVELRDGGKR-YHGKG 66
           I  V AR+ILDSRGNPTVEVDV     + GR AVPSGASTG +EAVELRDG K+ Y GKG
Sbjct: 57  IKVVKARQILDSRGNPTVEVDVILDNGVVGRGAVPSGASTGEYEAVELRDGDKKVYLGKG 116

Query: 67  VRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAA 126
           V ++V  VN ++AP+L+G+D   QREID L+ ++DGT NK  +GAN IL VS+A  +AAA
Sbjct: 117 VLKSVNAVNTLVAPKLIGLDPANQREIDELMKQIDGTPNKGKIGANGILGVSMACCRAAA 176

Query: 127 NALELPLYQYL----GGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182
               +PL++++    G  + + LPVP+ N+INGG HA N +DFQEFMIMPIGA SF E +
Sbjct: 177 LTQGIPLWKHIANLHGNKDNFQLPVPMCNIINGGKHADNKIDFQEFMIMPIGAKSFSEGL 236

Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242
           RWV+E +H LK ++  K   +  +VGDEGGFAP +    E L+ ++KAI+ AGY PG +I
Sbjct: 237 RWVTEIFHTLKALL--KKAGHVTSVGDEGGFAPDLSN-DEALEFVMKAIKAAGYTPGTQI 293

Query: 243 ALALDAASSEFYKDG-----KYIVSG--KEYTREELLELYKELTSTYPIVSIEDPFHEED 295
            +ALD ASSE + +G     K+  S   K ++ +E+++++      YPIVSIEDP  + D
Sbjct: 294 GVALDCASSELFDEGGRKGYKFWKSNPSKLFSAQEMIDIFCRWCDEYPIVSIEDPLDQND 353

Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355
           W+G+V +T+++G++ QIVGDD FVTNP R  KGI M A NA+L+KVNQIGT++E ++   
Sbjct: 354 WDGYVNMTKKMGRRTQIVGDDFFVTNPARFSKGIGMNACNAILIKVNQIGTVSETLECIK 413

Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415
           MA   GYG + SHRSGETEDA IADLAV    GQIKTG+ +R+DR AKYNQLIRIEEEL 
Sbjct: 414 MAQAHGYGSIASHRSGETEDAFIADLAVGTGCGQIKTGSLSRTDRMAKYNQLIRIEEELG 473

Query: 416 GVAVYAGKN 424
             A +  K+
Sbjct: 474 AQAKWTTKH 482


>pir||H83191 enolase PA3635 [imported] - Pseudomonas aeruginosa (strain PAO1)
           >gi|9949794|gb|AAG07023.1|AE004783_8 (AE004783) enolase
           [Pseudomonas aeruginosa]
           Length = 429
           
 Score =  436 bits (1110), Expect = e-121
 Identities = 235/424 (55%), Positives = 298/424 (69%), Gaps = 10/424 (2%)

Query: 8   EIVAVIAREILDSRGNPTVEVDVHTPISM-GRAAVPSGASTGTHEAVELRDGGK-RYHGK 65
           +IV +  RE+LDSRGNPTVE DV     + G A  PSGASTG+ EA+ELRDG K RY GK
Sbjct: 3   KIVDIKGREVLDSRGNPTVEADVILDNGIVGSACAPSGASTGSREALELRDGDKSRYLGK 62

Query: 66  GVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
           GV +AV N+N  I   L+G D   Q+ +D  +IELDGTENK+ LGANAILAVSLA AKAA
Sbjct: 63  GVLKAVANINGPIRDLLLGKDAADQKALDHAMIELDGTENKAKLGANAILAVSLAAAKAA 122

Query: 126 ANALELPLYQYLGGVNA----YVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREA 181
           A A  +PLY ++  +N     Y +PVP+ N+INGG HA N++D QEFM+ P+GA +F EA
Sbjct: 123 AQAKGVPLYAHIADLNGTPGQYSMPVPMMNIINGGEHADNNVDIQEFMVQPVGAKNFAEA 182

Query: 182 IRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEE 241
           +R  +E +H LK V+  + G N   VGDEGGFAP +    + L  + +A+E+AGYK G++
Sbjct: 183 LRMGAEIFHHLKAVLKAR-GLNTA-VGDEGGFAPNLSSNEDALAAIAEAVEKAGYKLGDD 240

Query: 242 IALALDAASSEFYKDGKYIVSG--KEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGF 299
           + LALD ASSEF+KDGKY + G  K +      +    LT  YPI+SIED   E DW G+
Sbjct: 241 VTLALDCASSEFFKDGKYDLEGEGKVFDAAGFADYLAGLTQRYPIISIEDGMDESDWAGW 300

Query: 300 VMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFR 359
             +T ++G KVQ+VGDDLFVTN K LK+GIE G  N++L+K NQIG+LTE ++A  MA  
Sbjct: 301 KGLTDKIGAKVQLVGDDLFVTNTKILKEGIEKGIGNSILIKFNQIGSLTETLEAIQMAKA 360

Query: 360 AGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAV 419
           AGY  V+SHRSGETED+TIADLAV   AGQIKTG+  RSDR +KYNQL+RIEE+L   A 
Sbjct: 361 AGYTAVISHRSGETEDSTIADLAVGTAAGQIKTGSLCRSDRVSKYNQLLRIEEQLGAKAP 420

Query: 420 YAGK 423
           Y G+
Sbjct: 421 YRGR 424


>gi|6978811 muscle specific enolase (beta beta enolose) (two splicing products)
           [Rattus norvegicus] >gi|119346|sp|P15429|ENOB_RAT BETA
           ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (SKELETAL
           MUSCLE ENOLASE) >gi|92214|pir||S02072 phosphopyruvate
           hydratase (EC 4.2.1.11) beta - rat
           >gi|57782|emb|CAA68788.1| (Y00979) beta beta enolase (AA
           1-434) [Rattus norvegicus]
           Length = 434
           
 Score =  436 bits (1109), Expect = e-121
 Identities = 241/428 (56%), Positives = 299/428 (69%), Gaps = 17/428 (3%)

Query: 12  VIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRA 70
           + AREILDSRGNPTVEVD+HT     RAAVPSGASTG +EA+ELRDG K RY GKGV +A
Sbjct: 6   IFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKSRYLGKGVPKA 65

Query: 71  VENVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANA 128
           VE++NK + P L+   + V  Q ++D+ +IELDGTENKS  GANAIL VSLAV KA A  
Sbjct: 66  VEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAE 125

Query: 129 LELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWV 185
             +PLY++   L G    VLPVP  NVINGG HAGN L  QEFMI+P+GA  F+ + R  
Sbjct: 126 KGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGAKLFQGSQRIG 185

Query: 186 SETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALA 245
           +E YH LK VI  KYGK+A NVGDEGGFAP + E  E L++L  AI+ AGY   +++ + 
Sbjct: 186 AEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYP--DKVVIG 243

Query: 246 LDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEEDWEG 298
           +D A+SEFY++GKY +  K         + E+L E YK     YP+VSIEDPF ++DW  
Sbjct: 244 MDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGEPYKSFIKNYPVVSIEDPFDQDDWAT 303

Query: 299 FVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAF 358
           +       G  +QIVGDDL VTNPKR+ + +E  A N LLLKVNQIG++TE++ A  +A 
Sbjct: 304 WTSFLS--GVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESILACKLAQ 361

Query: 359 RAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVA 418
             G+GV+VSHRSGETED  +ADL V L  GQIKTGAP RS+R AKYNQL+RIEE L   A
Sbjct: 362 SNGWGVMVSHRSGETEDTFVADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKA 421

Query: 419 VYAGKNFR 426
           V+AG+ FR
Sbjct: 422 VFAGRKFR 429


>gi|6321693 enolase I; Eno1p [Saccharomyces cerevisiae] >gi|2144536|pir||NOBY
           phosphopyruvate hydratase (EC 4.2.1.11) 1 [validated] -
           yeast (Saccharomyces cerevisiae)
           >gi|1323462|emb|CAA97283.1| (Z73039) ORF YGR254w
           [Saccharomyces cerevisiae] >gi|1502357|emb|CAA67616.1|
           (X99228) G9160 [Saccharomyces cerevisiae]
           Length = 437
           
 Score =  436 bits (1109), Expect = e-121
 Identities = 242/430 (56%), Positives = 300/430 (69%), Gaps = 20/430 (4%)

Query: 12  VIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRA 70
           V AR + DSRGNPTVEV++ T   + R+ VPSGASTG HEA+E+RDG K ++ GKGV  A
Sbjct: 6   VYARSVYDSRGNPTVEVELTTEKGVFRSIVPSGASTGVHEALEMRDGDKSKWMGKGVLHA 65

Query: 71  VENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANA 128
           V+NVN +IAP  V   +DV+ Q+ +D  LI LDGT NKS LGANAIL VSLA ++AAA  
Sbjct: 66  VKNVNDVIAPAFVKANIDVKDQKAVDDFLISLDGTANKSKLGANAILGVSLAASRAAAAE 125

Query: 129 LELPLYQYLGGVNA-----YVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIR 183
             +PLY++L  ++      YVLPVP  NV+NGG HAG  L  QEFMI P GA +F EA+R
Sbjct: 126 KNVPLYKHLADLSKSKTSPYVLPVPFLNVLNGGSHAGGALALQEFMIAPTGAKTFAEALR 185

Query: 184 WVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIA 243
             SE YH LK +  ++YG +A NVGDEGG AP ++   E LD+++ AI+ AG+    +I 
Sbjct: 186 IGSEVYHNLKSLTKKRYGASAGNVGDEGGVAPNIQTAEEALDLIVDAIKAAGHDG--KIK 243

Query: 244 LALDAASSEFYKDGKYIVSGKE--------YTREELLELYKELTSTYPIVSIEDPFHEED 295
           + LD ASSEF+KDGKY +  K          T  +L +LY  L   YPIVSIEDPF E+D
Sbjct: 244 IGLDCASSEFFKDGKYDLDFKNPNSDKSKWLTGPQLADLYHSLMKRYPIVSIEDPFAEDD 303

Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355
           WE +    +  G  +QIV DDL VTNPKR+   IE  AA+ALLLKVNQIGTL+E++ AA 
Sbjct: 304 WEAWSHFFKTAG--IQIVADDLTVTNPKRIATAIEKKAADALLLKVNQIGTLSESIKAAQ 361

Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415
            +F AG+GV+VSHRSGETED  IADL V L  GQIKTGAPARS+R AK NQL+RIEEEL 
Sbjct: 362 DSFAAGWGVMVSHRSGETEDTFIADLVVGLRTGQIKTGAPARSERLAKLNQLLRIEEELG 421

Query: 416 GVAVYAGKNF 425
             AV+AG+NF
Sbjct: 422 DNAVFAGENF 431


>sp|P00924|ENO1_YEAST ENOLASE 1 (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|171455|gb|AAA88712.1| (J01322) enolase
           [Saccharomyces cerevisiae]
           Length = 437
           
 Score =  436 bits (1108), Expect = e-121
 Identities = 241/430 (56%), Positives = 300/430 (69%), Gaps = 20/430 (4%)

Query: 12  VIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRA 70
           V AR + DSRGNPTVEV++ T   + R+ VPSGASTG HEA+E+RDG K ++ GKGV  A
Sbjct: 6   VYARSVYDSRGNPTVEVELTTEKGVFRSIVPSGASTGVHEALEMRDGDKSKWMGKGVLHA 65

Query: 71  VENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANA 128
           V+NVN +IAP  V   +DV+ Q+ +D  LI LDGT NKS LGANAIL VSLA ++AAA  
Sbjct: 66  VKNVNDVIAPAFVKANIDVKDQKAVDDFLISLDGTANKSKLGANAILGVSLAASRAAAAE 125

Query: 129 LELPLYQYLGGVNA-----YVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIR 183
             +PLY++L  ++      YVLPVP  NV+NGG HAG  L  QEFMI P GA +F EA+R
Sbjct: 126 KNVPLYKHLADLSKSKTSPYVLPVPFLNVLNGGSHAGGALALQEFMIAPTGAKTFAEALR 185

Query: 184 WVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIA 243
             SE YH LK +  ++YG +A NVGDEGG AP ++   E LD+++ AI+ AG+    ++ 
Sbjct: 186 IGSEVYHNLKSLTKKRYGASAGNVGDEGGVAPNIQTAEEALDLIVDAIKAAGHDG--KVK 243

Query: 244 LALDAASSEFYKDGKYIVSGKE--------YTREELLELYKELTSTYPIVSIEDPFHEED 295
           + LD ASSEF+KDGKY +  K          T  +L +LY  L   YPIVSIEDPF E+D
Sbjct: 244 IGLDCASSEFFKDGKYDLDFKNPNSDKSKWLTGPQLADLYHSLMKRYPIVSIEDPFAEDD 303

Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355
           WE +    +  G  +QIV DDL VTNPKR+   IE  AA+ALLLKVNQIGTL+E++ AA 
Sbjct: 304 WEAWSHFFKTAG--IQIVADDLTVTNPKRIATAIEKKAADALLLKVNQIGTLSESIKAAQ 361

Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415
            +F AG+GV+VSHRSGETED  IADL V L  GQIKTGAPARS+R AK NQL+RIEEEL 
Sbjct: 362 DSFAAGWGVMVSHRSGETEDTFIADLVVGLRTGQIKTGAPARSERLAKLNQLLRIEEELG 421

Query: 416 GVAVYAGKNF 425
             AV+AG+NF
Sbjct: 422 DNAVFAGENF 431


>pdb|1ONE|A Chain A, Yeast Enolase Complexed With An Equilibrium Mixture Of
           2'-Phosphoglyceate And Phosphoenolpyruvate
           >gi|1942653|pdb|1ONE|B Chain B, Yeast Enolase Complexed
           With An Equilibrium Mixture Of 2'-Phosphoglyceate And
           Phosphoenolpyruvate >gi|1065028|pdb|1EBH|A Chain A,
           Enolase (E.C.4.2.1.11) (2-Phospho-D-Glycerate Hydrolase)
           Complexed With Mg 2+ >gi|1065029|pdb|1EBH|B Chain B,
           Enolase (E.C.4.2.1.11) (2-Phospho-D-Glycerate Hydrolase)
           Complexed With Mg 2+ >gi|2914549|pdb|2ONE|A Chain A,
           Asymmetric Yeast Enolase Dimer Complexed With Resolved
           2'-Phosphoglycerate And Phosphoenolpyruvate
           >gi|2914550|pdb|2ONE|B Chain B, Asymmetric Yeast Enolase
           Dimer Complexed With Resolved 2'-Phosphoglycerate And
           Phosphoenolpyruvate >gi|1065025|pdb|1EBG|A Chain A,
           Enolase (E.C.4.2.1.11) (2-Phospho-D-Glycerate Hydrolase)
           (Apo Form) >gi|1065026|pdb|1EBG|B Chain B, Enolase
           (E.C.4.2.1.11) (2-Phospho-D-Glycerate Hydrolase) (Apo
           Form)
           Length = 436
           
 Score =  436 bits (1108), Expect = e-121
 Identities = 241/430 (56%), Positives = 300/430 (69%), Gaps = 20/430 (4%)

Query: 12  VIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRA 70
           V AR + DSRGNPTVEV++ T   + R+ VPSGASTG HEA+E+RDG K ++ GKGV  A
Sbjct: 5   VYARSVYDSRGNPTVEVELTTEKGVFRSIVPSGASTGVHEALEMRDGDKSKWMGKGVLHA 64

Query: 71  VENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANA 128
           V+NVN +IAP  V   +DV+ Q+ +D  LI LDGT NKS LGANAIL VSLA ++AAA  
Sbjct: 65  VKNVNDVIAPAFVKANIDVKDQKAVDDFLISLDGTANKSKLGANAILGVSLAASRAAAAE 124

Query: 129 LELPLYQYLGGVNA-----YVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIR 183
             +PLY++L  ++      YVLPVP  NV+NGG HAG  L  QEFMI P GA +F EA+R
Sbjct: 125 KNVPLYKHLADLSKSKTSPYVLPVPFLNVLNGGSHAGGALALQEFMIAPTGAKTFAEALR 184

Query: 184 WVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIA 243
             SE YH LK +  ++YG +A NVGDEGG AP ++   E LD+++ AI+ AG+    ++ 
Sbjct: 185 IGSEVYHNLKSLTKKRYGASAGNVGDEGGVAPNIQTAEEALDLIVDAIKAAGHDG--KVK 242

Query: 244 LALDAASSEFYKDGKYIVSGKE--------YTREELLELYKELTSTYPIVSIEDPFHEED 295
           + LD ASSEF+KDGKY +  K          T  +L +LY  L   YPIVSIEDPF E+D
Sbjct: 243 IGLDCASSEFFKDGKYDLDFKNPNSDKSKWLTGPQLADLYHSLMKRYPIVSIEDPFAEDD 302

Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355
           WE +    +  G  +QIV DDL VTNPKR+   IE  AA+ALLLKVNQIGTL+E++ AA 
Sbjct: 303 WEAWSHFFKTAG--IQIVADDLTVTNPKRIATAIEKKAADALLLKVNQIGTLSESIKAAQ 360

Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415
            +F AG+GV+VSHRSGETED  IADL V L  GQIKTGAPARS+R AK NQL+RIEEEL 
Sbjct: 361 DSFAAGWGVMVSHRSGETEDTFIADLVVGLRTGQIKTGAPARSERLAKLNQLLRIEEELG 420

Query: 416 GVAVYAGKNF 425
             AV+AG+NF
Sbjct: 421 DNAVFAGENF 430


>pdb|4ENL|   Enolase (E.C.4.2.1.11) (2-Phospho-D-Glycerate Hydrolase) (Holo)
           >gi|231132|pdb|5ENL|  Enolase (E.C.4.2.1.11)
           (2-Phospho-D-Glycerate Hydrolase) Complex With
           2-Phospho-D-Glyceric Acid And Calcium
           >gi|231208|pdb|6ENL|  Enolase (E.C.4.2.1.11)
           (2-Phospho-D-Glycerate Hydrolase) Complex With
           Phosphoglycolic Acid And Zinc >gi|231253|pdb|7ENL|
           Enolase (E.C.4.2.1.11) (2-Phospho-D-Glycerate Hydrolase)
           Complex With 2-Phospho-D-Glyceric Acid And Magnesium
           >gi|230846|pdb|3ENL|  Enolase (E.C.4.2.1.11)
           (2-Phospho-D-Glycerate Hydrolase) (Apo)
           >gi|576098|pdb|1ELS|  Enolase (E.C.4.2.1.11)
           (2-Phospho-D-Glycerate Hydrolase) Complexed With
           Phosphonoacetohydroxamate And Manganese
           >gi|494413|pdb|1NEL|  Enolase (E.C.4.2.1.11)
           (2-Phospho-D-Glycerate Hydrolase) Complex With
           Orthophosphate, Fluoride And Magnesium
           Length = 436
           
 Score =  434 bits (1105), Expect = e-121
 Identities = 241/430 (56%), Positives = 299/430 (69%), Gaps = 20/430 (4%)

Query: 12  VIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRA 70
           V AR + DSRGNPTVEV++ T   + R+ VPSGASTG HEA+E+RDG K ++ GKGV  A
Sbjct: 5   VYARSVYDSRGNPTVEVELTTEKGVFRSIVPSGASTGVHEALEMRDGDKSKWMGKGVLHA 64

Query: 71  VENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANA 128
           V+NVN +IAP  V   +DV  Q+ +D  LI LDGT NKS LGANAIL VSLA ++AAA  
Sbjct: 65  VKNVNDVIAPAFVKANIDVSDQKAVDDFLISLDGTANKSKLGANAILGVSLAASRAAAAE 124

Query: 129 LELPLYQYLGGVNA-----YVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIR 183
             +PLY++L  ++      YVLPVP  NV+NGG HAG  L  QEFMI P GA +F EA+R
Sbjct: 125 KNVPLYKHLADLSKSKTSPYVLPVPFLNVLNGGSHAGGALALQEFMIAPTGAKTFAEALR 184

Query: 184 WVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIA 243
             SE YH LK +  ++YG +A NVGDEGG AP ++   E LD+++ AI+ AG+    ++ 
Sbjct: 185 IGSEVYHNLKSLTKKRYGASAGNVGDEGGVAPNIQTAEEALDLIVDAIKAAGHDG--KVK 242

Query: 244 LALDAASSEFYKDGKYIVSGKE--------YTREELLELYKELTSTYPIVSIEDPFHEED 295
           + LD ASSEF+KDGKY +  K          T  +L +LY  L   YPIVSIEDPF E+D
Sbjct: 243 IGLDCASSEFFKDGKYDLDFKNPNSDKSKWLTGPQLADLYHSLMKRYPIVSIEDPFAEDD 302

Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355
           WE +    +  G  +QIV DDL VTNPKR+   IE  AA+ALLLKVNQIGTL+E++ AA 
Sbjct: 303 WEAWSHFFKTAG--IQIVADDLTVTNPKRIATAIEKKAADALLLKVNQIGTLSESIKAAQ 360

Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415
            +F AG+GV+VSHRSGETED  IADL V L  GQIKTGAPARS+R AK NQL+RIEEEL 
Sbjct: 361 DSFAAGWGVMVSHRSGETEDTFIADLVVGLRTGQIKTGAPARSERLAKLNQLLRIEEELG 420

Query: 416 GVAVYAGKNF 425
             AV+AG+NF
Sbjct: 421 DNAVFAGENF 430


>gb|AAD02812.1| (AF063247) enolase [Pneumocystis carinii f. sp. ratti]
           Length = 433
           
 Score =  433 bits (1102), Expect = e-120
 Identities = 233/433 (53%), Positives = 300/433 (68%), Gaps = 19/433 (4%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGKRYHGKGVR 68
           I  + AR   DSRGNPTVEV+V T   + RA VPSGASTG HEA+ELRD G  + GKGV 
Sbjct: 3   IFKIHARSFYDSRGNPTVEVEVTTETGVHRANVPSGASTGIHEALELRDNGSSWSGKGVT 62

Query: 69  RAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAA 126
            AV NVN IIAP L+  G+D++ QR ID+ LI+LDGT NKS LGANAIL VS+A+ KAAA
Sbjct: 63  LAVSNVNDIIAPSLLSAGIDIKDQRSIDKFLIDLDGTSNKSRLGANAILGVSIAICKAAA 122

Query: 127 NALELPLYQYLGGV----NAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182
               +PLY++   +      ++LP+P  NV+NGG HAG  L FQEFMI+P  A +F EA+
Sbjct: 123 AEKGVPLYRHFADIADIKEPFILPLPCFNVLNGGSHAGGRLAFQEFMILPTSAVTFHEAM 182

Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242
           +  SE Y  LKK+  ++YG +A N GDEGG AP ++   E LD+++ AIEEAGY    +I
Sbjct: 183 QQGSEVYSALKKLSRKRYGHSAGNAGDEGGVAPDIQTADEALDLIVTAIEEAGYTG--KI 240

Query: 243 ALALDAASSEFYKDGKYIV--------SGKEYTREELLELYKELTSTYPIVSIEDPFHEE 294
            +ALD A+SEFYK+GKY +        S +  T +EL ++Y +L+  YPIVSIE+P   +
Sbjct: 241 KIALDVAASEFYKNGKYDLDFKNPESDSSQHKTSKELADIYLDLSKKYPIVSIENPVDRD 300

Query: 295 DWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAA 354
           DW+ ++ ++R      Q+VGDDL VTN  R+ +  +  A N LLLK+NQIGT++E++DA 
Sbjct: 301 DWDAWIYVSRRA--TFQMVGDDLTVTNVSRINEAADKKACNCLLLKINQIGTISESIDAF 358

Query: 355 YMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEEL 414
             AF AG+GV+VSHRSGETED  IADL V L  GQIKTGAP RS+R AKYNQL+RIEEEL
Sbjct: 359 KTAFDAGWGVMVSHRSGETEDTVIADLVVGLGTGQIKTGAPCRSERVAKYNQLLRIEEEL 418

Query: 415 EGVAVYAGKNFRK 427
              +VYA  N+ K
Sbjct: 419 NH-SVYASMNYIK 430


>sp|P07322|ENOB_CHICK BETA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (PHOSPHOPYRUVATE
           HYDRATASE) >gi|1085244|pir||JC4187 phosphopyruvate
           hydratase (EC 4.2.1.11) beta chain - chicken
           >gi|1616990|dbj|BAA07133.1| (D37901) enolase [Gallus
           gallus]
           Length = 434
           
 Score =  433 bits (1101), Expect = e-120
 Identities = 238/431 (55%), Positives = 299/431 (69%), Gaps = 17/431 (3%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67
           I  + AREILDSRG PTVEVD+HT     RAAVPSGASTG HEA+E RDG K R+ GKGV
Sbjct: 3   IQKIHAREILDSRGEPTVEVDLHTAKGHFRAAVPSGASTGIHEALEPRDGDKKRFLGKGV 62

Query: 68  RRAVENVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
            +AVE++NK I P L+   + V  Q +ID+++IE+DGTENKS  GANAIL VSLAV KA 
Sbjct: 63  LKAVEHINKTIGPALIEKKISVVEQEKIDKVMIEMDGTENKSKFGANAILGVSLAVCKAG 122

Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182
           A    +PLY++   L G    +LPVP  NVINGG HAGN L  QEFM++P+GA SF +A+
Sbjct: 123 AAEKGVPLYRHIADLAGNTELILPVPAFNVINGGSHAGNKLAMQEFMVLPVGAASFHDAM 182

Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242
           R  +E YH LK VI  KYGK+A NVG EGGFAP + +  E L++L  AI +AGY   +++
Sbjct: 183 RVGAEVYHSLKGVIKAKYGKDATNVGGEGGFAPNILDNHEALELLKAAIAQAGYT--DKV 240

Query: 243 ALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEED 295
            + +D A+SEF +DG+Y +  K         T E+L E+Y+     YP+VSIEDPF ++D
Sbjct: 241 VIGMDVAASEFCRDGRYHLDFKSPPHTKRYITGEQLGEIYRGFIKDYPVVSIEDPFDQDD 300

Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355
           WE +      +   +Q+VGDDL VTNPKR+  G E  A N LLLKVNQIG++TE++ A  
Sbjct: 301 WEAWKRFVFHVD--IQVVGDDLTVTNPKRIAHGAEQHACNCLLLKVNQIGSVTESIQACK 358

Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415
           +A   G+GV+VSHRSGETED  IADL V L  GQIKTGAP RS+R AKYNQL+RIEE L 
Sbjct: 359 LAQSHGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALG 418

Query: 416 GVAVYAGKNFR 426
             A +AG+ FR
Sbjct: 419 DKAKFAGRKFR 429


>sp|O52191|ENO_STRTR ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|2921237|gb|AAC64907.1| (AF027167)
           enolase [Streptococcus thermophilus]
           Length = 422
           
 Score =  432 bits (1100), Expect = e-120
 Identities = 230/418 (55%), Positives = 300/418 (71%), Gaps = 13/418 (3%)

Query: 1   MTMENPYEIVAVIAREILDSRGNPTVEVDVH-TPISMGRAAVPSGASTGTHEAVELRDGG 59
           +T+EN      + AREI DSRGNPTVEVDV  T  ++GRAAVPSGASTG  EAVELRDGG
Sbjct: 3   VTIEN------IHAREIFDSRGNPTVEVDVRLTDGTLGRAAVPSGASTGDREAVELRDGG 56

Query: 60  KRYHGKGVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSL 119
            R  GKGV +AV NVN  I   L G     Q ++D L+IELDGTENKS LGANAIL VS+
Sbjct: 57  ARLQGKGVSKAVANVNGEIYEALKGQSPFNQAKLDHLMIELDGTENKSCLGANAILGVSM 116

Query: 120 AVAKAAANALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFR 179
           A+ +AAAN+ ++PLY+Y GGV+   LP P  NVINGGVHA + +D QEF+I P+  +SFR
Sbjct: 117 AIFRAAANSEKIPLYRYFGGVDLE-LPQPFFNVINGGVHADSGIDVQEFLITPVKRDSFR 175

Query: 180 EAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPG 239
           + ++ ++  YH LKK++++K  K  V  GDEGGFAP +      + +L + I+ AGY PG
Sbjct: 176 DGLKKIANIYHTLKKILSDKGLKTPV--GDEGGFAPKLGTTENAIAILYQPIDSAGYFPG 233

Query: 240 EEIALALDAASSEFYKDGK--YIVSGKEYTREELLELYKELTSTYP-IVSIEDPFHEEDW 296
           E+IA+A+D++S EFY D K  Y   GK  T +ELL  Y  L   YP ++SIED F E DW
Sbjct: 234 EKIAIAIDSSSIEFYDDKKKFYRFEGKNLTSKELLTYYDNLVEKYPALISIEDGFSEHDW 293

Query: 297 EGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYM 356
           EGF   T+  G+K+Q+VGDD+FVTNP   K+GI+   ANA+L+K+NQIGT+TE ++   +
Sbjct: 294 EGFAAQTKARGQKIQLVGDDIFVTNPTIFKEGIKKNVANAILIKLNQIGTVTETIETISL 353

Query: 357 AFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEEL 414
           A +AGY  ++SHRSGET D+ IAD +VA++AGQIK+G+ ARS+R  KYNQL+RIEE+L
Sbjct: 354 ARKAGYKTMISHRSGETVDSYIADFSVAMHAGQIKSGSMARSERVEKYNQLLRIEEDL 411


>gb|AAF51344.1| (AE003585) Eno gene product [Drosophila melanogaster]
           Length = 433
           
 Score =  432 bits (1099), Expect = e-120
 Identities = 238/433 (54%), Positives = 298/433 (67%), Gaps = 18/433 (4%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67
           I A+ AR+I DSRGNPTVEVD+ T + + RAAVPSGASTG HEA+ELRD  K  YHGK V
Sbjct: 3   IKAIKARQIYDSRGNPTVEVDLTTELGLFRAAVPSGASTGVHEALELRDNDKANYHGKSV 62

Query: 68  RRAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
            +AV +VN  + PEL+   +DV  Q  ID  +I+LDGTENKS  GANAIL VSLAVAKA 
Sbjct: 63  LKAVGHVNDTLGPELIKANLDVVDQASIDNFMIKLDGTENKSKFGANAILGVSLAVAKAG 122

Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182
           A    +PLY++   L G    +LPVP  NVINGG HAGN L  QEFMI+P GA SF EA+
Sbjct: 123 AAKKGVPLYKHIADLAGNKEIILPVPAFNVINGGSHAGNKLAMQEFMILPTGATSFTEAM 182

Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242
           +  SE YH LK VI  K+G +A  VGDEGGFAP ++   E L+++  AI +AGY    +I
Sbjct: 183 KMGSEVYHHLKNVIKAKFGLDATAVGDEGGFAPNIQSNKEALNLISDAIAKAGYTG--KI 240

Query: 243 ALALDAASSEFYKDGKYIVSGKE--------YTREELLELYKELTSTYPIVSIEDPFHEE 294
            + +D A+SEFYKDG+Y +  K            ++L  LY+E    +PIVSIEDPF ++
Sbjct: 241 EIGMDVAASEFYKDGQYDLDFKNEKSDKSQWLPADKLANLYQEFIKDFPIVSIEDPFDQD 300

Query: 295 DWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAA 354
            WE +  +T      +QIVGDDL VTNPKR+   +E  A N LLLKVNQIGT+TE++ A 
Sbjct: 301 HWEAWSNLTG--CTDIQIVGDDLTVTNPKRIATAVEKKACNCLLLKVNQIGTVTESIAAH 358

Query: 355 YMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEEL 414
            +A + G+G +VSHRSGETED+ I DL V L+ GQIKTGAP RS+R AKYNQ++RIEEE+
Sbjct: 359 LLAKKNGWGTMVSHRSGETEDSFIGDLVVGLSTGQIKTGAPCRSERLAKYNQILRIEEEI 418

Query: 415 EGVAVYAGKNFRK 427
                +AGK+FRK
Sbjct: 419 GAGVKFAGKSFRK 431


>pir||I56569 gamma enolase - human (fragment) >gi|182118|gb|AAA52388.1| (M36768)
           gamma enolase [Homo sapiens]
           Length = 408
           
 Score =  431 bits (1097), Expect = e-120
 Identities = 232/402 (57%), Positives = 292/402 (71%), Gaps = 17/402 (4%)

Query: 38  RAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRAVENVNKIIAPELV--GMDVRWQREID 94
           RAAVPSGASTG +EA+ELRDG K RY GKGV +AV+++N  IAP L+  G+ V  Q ++D
Sbjct: 6   RAAVPSGASTGIYEALELRDGDKQRYLGKGVLKAVDHINSTIAPALISSGLSVVEQEKLD 65

Query: 95  RLLIELDGTENKSNLGANAILAVSLAVAKAAANALELPLYQY---LGGVNAYVLPVPLSN 151
            L++ELDGTENKS  GANAIL VSLAV KA A    LPLY++   L G +  +LPVP  N
Sbjct: 66  NLMLELDGTENKSKFGANAILGVSLAVCKAGAAERNLPLYRHIAQLAGNSDLILPVPAFN 125

Query: 152 VINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVSETYHVLKKVIAEKYGKNAVNVGDEG 211
           VINGG HAGN L  QEFMI+P+GA SFR+A+R  +E YH LK VI +KYGK+A NVGDEG
Sbjct: 126 VINGGSHAGNKLAMQEFMILPVGAESFRDAMRLGAEVYHTLKGVIKDKYGKDATNVGDEG 185

Query: 212 GFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALALDAASSEFYKDGKYIVSGKE------ 265
           GFAP + E +E L+++ +AI++AGY   E+I + +D A+SEFY+DGKY +  K       
Sbjct: 186 GFAPNILENSEALELVKEAIDKAGYT--EKIVIGMDVAASEFYRDGKYDLDFKSPTDPSR 243

Query: 266 -YTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKR 324
             T ++L  LY++    YP+VSIEDPF ++DW  +   T  +G  +QIVGDDL VTNPKR
Sbjct: 244 YITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVG--IQIVGDDLTVTNPKR 301

Query: 325 LKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVA 384
           +++ +E  A N LLLKVNQIG++TEA+ A  +A   G+GV+VSHRSGETED  IADL V 
Sbjct: 302 IERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVG 361

Query: 385 LNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAGKNFR 426
           L  GQIKTGAP RS+R AKYNQL+RIEEEL   A +AG NFR
Sbjct: 362 LCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARFAGHNFR 403


>sp|P15007|ENO_DROME ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|84950|pir||S07586 phosphopyruvate
           hydratase (EC 4.2.1.11) - fruit fly  (Drosophila
           melanogaster) >gi|7946|emb|CAA34895.1| (X17034) enolase
           (AA 1-433) [Drosophila melanogaster]
           Length = 433
           
 Score =  431 bits (1096), Expect = e-120
 Identities = 238/433 (54%), Positives = 297/433 (67%), Gaps = 18/433 (4%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67
           I A+ AR+I DSRGNPTVEVD+ T + + RAAVPSGASTG HEA+ELRD  K  YHGK V
Sbjct: 3   IKAIKARQIYDSRGNPTVEVDLTTELGLFRAAVPSGASTGVHEALELRDNDKANYHGKSV 62

Query: 68  RRAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
            +AV +VN  + PEL+   +DV  Q  ID  +I+LDGTENKS  GANAIL VSLAVAKA 
Sbjct: 63  LKAVGHVNDTLGPELIKANLDVVDQASIDNFMIKLDGTENKSKFGANAILGVSLAVAKAG 122

Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182
           A    +PLY++   L G    +LPVP  NVINGG HAGN L  QEFMI+P GA SF EA+
Sbjct: 123 AAKKGVPLYKHIADLAGNKEIILPVPAFNVINGGSHAGNKLAMQEFMILPTGATSFTEAM 182

Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242
           +  SE YH LK VI  K+G +A  VGDEGGFAP ++   E L+++  AI +AGY    +I
Sbjct: 183 KMGSEVYHHLKNVIKAKFGLDATAVGDEGGFAPNIQSNKEALNLISDAIAKAGYTG--KI 240

Query: 243 ALALDAASSEFYKDGKYIVSGKE--------YTREELLELYKELTSTYPIVSIEDPFHEE 294
            + +D A+SEFYKDG+Y +  K            ++L  LYKE    +PIVSIEDPF ++
Sbjct: 241 EIGMDVAASEFYKDGQYDLDFKNEKSDKSQWLPADKLANLYKEFIKDFPIVSIEDPFDQD 300

Query: 295 DWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAA 354
            WE +  +T      +QIVGDDL VTNPKR+   +E  A N LLLKVNQIGT+TE++ A 
Sbjct: 301 HWEAWSNLTG--CTDIQIVGDDLTVTNPKRIATAVEKKACNCLLLKVNQIGTVTESIAAH 358

Query: 355 YMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEEL 414
            +A + G+G +VSHRSGETED+ I DL V L+ GQIKTGAP RS+R AKYNQ++RIEEE+
Sbjct: 359 LLAKKNGWGTMVSHRSGETEDSFIGDLVVGLSTGQIKTGAPCRSERLAKYNQILRIEEEI 418

Query: 415 EGVAVYAGKNFRK 427
                +AGK+F K
Sbjct: 419 GAGVKFAGKSFGK 431


>sp|P51555|ENO1_ENTHI ENOLASE 1 (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|498862|gb|AAA80166.1| (U09736) enolase
           [Entamoeba histolytica]
           Length = 436
           
 Score =  430 bits (1095), Expect = e-119
 Identities = 241/434 (55%), Positives = 294/434 (67%), Gaps = 20/434 (4%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67
           I  V AREILDSRGNPT+EV++ T   M R+ VPSGASTG HEAVELRDG K RY GKGV
Sbjct: 3   IQKVHAREILDSRGNPTIEVEITTGKGMFRSCVPSGASTGVHEAVELRDGDKKRYGGKGV 62

Query: 68  RRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAAN 127
            +AVENVN II P L+G +V  Q E+D ++I+LDGT NK  LGANAIL  S+++ +AAA 
Sbjct: 63  LKAVENVNTIIGPALLGKNVLNQAELDEMMIKLDGTNNKGKLGANAILGCSMSICRAAAA 122

Query: 128 ALELPLYQYLGGVNAY---VLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRW 184
              LPLY+YL  +  +    +PVP  NVINGG HAGN L  QEFMI P GA +F EA+R 
Sbjct: 123 EKGLPLYKYLAELTGHKEMTMPVPCFNVINGGAHAGNALAMQEFMICPTGATNFHEALRM 182

Query: 185 VSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIAL 244
            +ETY  LK VI  KYG++A NVGDEGGFAP +    E LD+L++AI +AGY    +I +
Sbjct: 183 AAETYQCLKVVIKAKYGQDATNVGDEGGFAPNVSGAREALDLLVEAIAKAGYTG--KIEI 240

Query: 245 ALDAASSEFYKD-------GKYIVSGKEYTR-----EELLELYKELTSTYPIVSIEDPFH 292
           A+D A+SEFY +       GK I + K+        + L+  Y +    YPI SIEDPF 
Sbjct: 241 AMDCAASEFYNEETKKYDLGKKIPADKKDPSLVKDVDGLIAEYVDYGKHYPIASIEDPFA 300

Query: 293 EEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMD 352
           E+DW  +   T E G   QIVGDDL VTNP R++  ++  A N++L+KVNQIGTLTE   
Sbjct: 301 EDDWAAWNKFTVEHGN-FQIVGDDLLVTNPARVQMAMDKNACNSVLIKVNQIGTLTETFK 359

Query: 353 AAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEE 412
              MA   G+GV+ SHRSGETED  IADL V LN  QIKTGAP RS+R  KYNQL+RIEE
Sbjct: 360 TIKMAQEKGWGVMASHRSGETEDTFIADLVVGLNCKQIKTGAPCRSERLCKYNQLMRIEE 419

Query: 413 ELEGVAVYAGKNFR 426
           EL G   YAGKN+R
Sbjct: 420 EL-GNIPYAGKNWR 432


>gb|AAD51128.1|AF051910_1 (AF051910) enolase [Toxoplasma gondii]
           Length = 444
           
 Score =  430 bits (1095), Expect = e-119
 Identities = 237/437 (54%), Positives = 309/437 (70%), Gaps = 24/437 (5%)

Query: 12  VIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGG-KRYHGKGVRRA 70
           ++AREILDSRGNPT+EVDV T   + RAAVPSGASTG +EA+ELRD   KRY GKGV  A
Sbjct: 7   IVAREILDSRGNPTIEVDVSTEGGVFRAAVPSGASTGIYEALELRDKDPKRYLGKGVLNA 66

Query: 71  VENVNKIIAPELVGMDVRWQREIDRLLIE-LDGTEN-----KSNLGANAILAVSLAVAKA 124
           VE V + I P L+G D   Q+ ID L++E LDGT+N     KS LGANAIL VS+A  +A
Sbjct: 67  VEIVRQEIKPALLGKDPCDQKGIDMLMVEQLDGTKNEWGYSKSKLGANAILGVSIACCRA 126

Query: 125 AANALELPLYQYLGG-----VNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFR 179
            A +  LPLY+Y+       ++  V+PVP  NVINGG HAGN L  QEF+I P+GA + R
Sbjct: 127 GAASKGLPLYKYIATLAGKTIDKMVMPVPFFNVINGGEHAGNGLALQEFLIAPVGAPNIR 186

Query: 180 EAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPG 239
           EAIR+ SETYH LK VI  KYG +A NVGDEGGFAP +    E L++L++AI+ AGY+  
Sbjct: 187 EAIRYGSETYHHLKNVIKNKYGLDATNVGDEGGFAPNVATAEEALNLLVEAIKAAGYEG- 245

Query: 240 EEIALALDAASSEFYK--DGKYIV--------SGKEYTREELLELYKELTSTYPIVSIED 289
            +I +A DAA+SEFYK  + KY +        + K  T E+L E+Y+     YPI+S+ED
Sbjct: 246 -KIKIAFDAAASEFYKQDEKKYDLDYKCKTKNASKHLTGEKLKEVYEGWLKKYPIISVED 304

Query: 290 PFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTE 349
           PF ++D+  F   T+++G+K Q++GDD+ VTN  R++K ++  A N LLLKVNQIG++TE
Sbjct: 305 PFDQDDFASFSAFTKDVGEKTQVIGDDILVTNILRIEKALKDKACNCLLLKVNQIGSVTE 364

Query: 350 AMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIR 409
           A++A  +A ++G+GV VSHRSGETED+ IADL V L  GQIK+G+P RS+R  KYNQL+R
Sbjct: 365 AIEACLLAQKSGWGVQVSHRSGETEDSFIADLVVGLRCGQIKSGSPCRSERLCKYNQLMR 424

Query: 410 IEEELEGVAVYAGKNFR 426
           IEE L    VYAG++FR
Sbjct: 425 IEESLGADCVYAGESFR 441


>gi|6321968 enolase; Eno2p [Saccharomyces cerevisiae]
           >gi|119337|sp|P00925|ENO2_YEAST ENOLASE 2
           (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|68309|pir||NOBY2 phosphopyruvate
           hydratase (EC 4.2.1.11) 2 - yeast  (Saccharomyces
           cerevisiae) >gi|171457|gb|AAA88713.1| (J01323) enolase
           [Saccharomyces cerevisiae] >gi|458897|gb|AAB68019.1|
           (U00027) Eno2p: Enolase 2; 2-phosphoglycerate
           dehydratase [Saccharomyces cerevisiae]
           Length = 437
           
 Score =  428 bits (1089), Expect = e-119
 Identities = 238/430 (55%), Positives = 295/430 (68%), Gaps = 20/430 (4%)

Query: 12  VIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRA 70
           V AR + DSRGNPTVEV++ T   + R+ VPSGASTG HEA+E+RD  K ++ GKGV  A
Sbjct: 6   VYARSVYDSRGNPTVEVELTTEKGVFRSIVPSGASTGVHEALEMRDEDKSKWMGKGVMNA 65

Query: 71  VENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANA 128
           V NVN +IA   V   +DV+ Q+ +D  L+ LDGT NKS LGANAIL VS+A A+AAA  
Sbjct: 66  VNNVNNVIAAAFVKANLDVKDQKAVDDFLLSLDGTANKSKLGANAILGVSMAAARAAAAE 125

Query: 129 LELPLYQYLGGVNA-----YVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIR 183
             +PLYQ+L  ++      YVLPVP  NV+NGG HAG  L  QEFMI P GA +F EA+R
Sbjct: 126 KNVPLYQHLADLSKSKTSPYVLPVPFLNVLNGGSHAGGALALQEFMIAPTGAKTFAEAMR 185

Query: 184 WVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIA 243
             SE YH LK +  ++YG +A NVGDEGG AP ++   E LD+++ AI+ AG+    ++ 
Sbjct: 186 IGSEVYHNLKSLTKKRYGASAGNVGDEGGVAPNIQTAEEALDLIVDAIKAAGHDG--KVK 243

Query: 244 LALDAASSEFYKDGKYIVSGKE--------YTREELLELYKELTSTYPIVSIEDPFHEED 295
           + LD ASSEF+KDGKY +  K          T  EL ++Y  L   YPIVSIEDPF E+D
Sbjct: 244 IGLDCASSEFFKDGKYDLDFKNPESDKSKWLTGVELADMYHSLMKRYPIVSIEDPFAEDD 303

Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355
           WE +    +  G  +QIV DDL VTNP R+   IE  AA+ALLLKVNQIGTL+E++ AA 
Sbjct: 304 WEAWSHFFKTAG--IQIVADDLTVTNPARIATAIEKKAADALLLKVNQIGTLSESIKAAQ 361

Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415
            +F A +GV+VSHRSGETED  IADL V L  GQIKTGAPARS+R AK NQL+RIEEEL 
Sbjct: 362 DSFAANWGVMVSHRSGETEDTFIADLVVGLRTGQIKTGAPARSERLAKLNQLLRIEEELG 421

Query: 416 GVAVYAGKNF 425
             AVYAG+NF
Sbjct: 422 DKAVYAGENF 431


>emb|CAC16971.1| (AL450350) enolase [Streptomyces coelicolor]
           Length = 434
           
 Score =  428 bits (1089), Expect = e-119
 Identities = 230/420 (54%), Positives = 293/420 (69%), Gaps = 6/420 (1%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRDGGK-RYHGKG 66
           I  V AR I+DSRGNPTVEVDV     S+GRAAVPSGASTG  EAVELRD    R+HGKG
Sbjct: 12  IETVTARRIIDSRGNPTVEVDVVLEDGSLGRAAVPSGASTGAREAVELRDEDPTRWHGKG 71

Query: 67  VRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAA 126
           V RAV +VN  IA  + G D   Q  +D  LI LDGT  KS LGANA+L VSLA AKAAA
Sbjct: 72  VDRAVAHVNGEIAASVRGRDAADQAGLDAALIALDGTAAKSRLGANALLGVSLAAAKAAA 131

Query: 127 NALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVS 186
            A   PLY+YLGG +A++LP+P+ N++NGG HA N LDFQEFMI+P+GA++F EA+R  S
Sbjct: 132 AARRQPLYRYLGGADAHLLPLPMMNIVNGGAHADNPLDFQEFMIVPVGADTFAEAVRMGS 191

Query: 187 ETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALAL 246
           E +H L++ +      ++  VGDEGGFAP ++   E LD ++ AIE  GY+ G +I L +
Sbjct: 192 EVFHTLRRDLLA--AGHSTGVGDEGGFAPALRTAEEALDFVVAAIERTGYRAGPDIGLVM 249

Query: 247 DAASSEFYKDGKYIVSGKEYTRE--ELLELYKELTSTYPIVSIEDPFHEEDWEGFVMITR 304
           D ASSEF++DG Y  +G+   R   E  +    L   YP+VSIEDP  E+D +G+  +T 
Sbjct: 250 DPASSEFFRDGGYDYAGEGVRRSPAEHADHLAGLIDAYPVVSIEDPMAEDDLDGWRELTD 309

Query: 305 ELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYGV 364
            +G + Q+ GDD+F T+   +++GI  G  N++L+KVNQIGTLTEA+     A  AG+ V
Sbjct: 310 RVGDRCQLTGDDVFCTDEALVREGIRTGVGNSVLVKVNQIGTLTEALATVATAHEAGWTV 369

Query: 365 VVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAGKN 424
           V+SHRSGETED TIADLAVA   GQIKTG+ +RSDR AKYN+LIRIEEEL   A +AG++
Sbjct: 370 VMSHRSGETEDTTIADLAVATGCGQIKTGSLSRSDRTAKYNRLIRIEEELGASARFAGRS 429


>sp|P40370|ENO1_SCHPO ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|1076907|pir||JC4036 phosphopyruvate
           hydratase (EC 4.2.1.11) - fission yeast
           (Schizosaccharomyces pombe) >gi|535442|gb|AAA70080.1|
           (U13799) enolase [Schizosaccharomyces pombe]
           Length = 439
           
 Score =  427 bits (1086), Expect = e-118
 Identities = 233/434 (53%), Positives = 300/434 (68%), Gaps = 19/434 (4%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67
           I  V AR+I    GNPTVEVD+ T   + RA VPSGASTG  EA+E+RDG K ++ GKGV
Sbjct: 3   IQKVFARQIYALGGNPTVEVDLTTETGIHRAIVPSGASTGIWEALEMRDGDKTKWGGKGV 62

Query: 68  RRAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
            +AV NVN IIAP +V   +DV  Q+  D  L++LDGTENKS LGANAIL VS+A+ +A 
Sbjct: 63  LKAVGNVNNIIAPAVVKANLDVTDQKAADEFLLKLDGTENKSKLGANAILGVSMAICRAG 122

Query: 126 ANALELPLYQYL----GGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREA 181
           A   +LPL++Y+    G    YVLPVP  NV+NGG HAG DL FQEFMI+P GA SF EA
Sbjct: 123 AAQKKLPLWKYIAENFGTKGPYVLPVPSFNVLNGGSHAGGDLAFQEFMILPTGAPSFSEA 182

Query: 182 IRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEE 241
           +RW +ETY  LK +  ++YG +A NVGDEGG AP ++   E LD++++AI +AGY+   +
Sbjct: 183 MRWGAETYQTLKSIAKKRYGSSAGNVGDEGGIAPDLQTPQEALDLIVEAINKAGYEG--K 240

Query: 242 IALALDAASSEFYKDGKYIVSGK--------EYTREELLELYKELTSTYPIVSIEDPFHE 293
           I + LD  SSEFY DGKY +  K        + T ++L +LY EL+  YPIVSIEDPF +
Sbjct: 241 IKIGLDVTSSEFYVDGKYDLDIKAAKPKPENKLTYQQLTDLYVELSKKYPIVSIEDPFDQ 300

Query: 294 EDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDA 353
           +DW  +  +  E     QIVGDDL VTN KRL+  I+   ANALLLKVNQIG++TE+++ 
Sbjct: 301 DDWSAWTHMKAETD--FQIVGDDLTVTNVKRLRTAIDKKCANALLLKVNQIGSVTESLNV 358

Query: 354 AYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEE 413
             M++ AG+GV+VSHRSG T D  I+ L V + AGQ+K+GAP RS+R AKYN+L+RIEEE
Sbjct: 359 VRMSYEAGWGVMVSHRSGGTADTFISHLTVGIGAGQLKSGAPCRSERLAKYNELLRIEEE 418

Query: 414 LEGVAVYAGKNFRK 427
           L    VYAG +  K
Sbjct: 419 LGSRGVYAGAHAGK 432


>pir||A23850 phosphopyruvate hydratase (EC 4.2.1.11), skeletal muscle - chicken
           Length = 433
           
 Score =  426 bits (1084), Expect = e-118
 Identities = 234/431 (54%), Positives = 298/431 (68%), Gaps = 17/431 (3%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67
           I  + AREILDSRG+PTVEVD+HT     RAAVPSGASTG HEA+ELRDG K R+ GKGV
Sbjct: 2   IQKIHAREILDSRGDPTVEVDLHTAKGHFRAAVPSGASTGIHEALELRDGDKKRFLGKGV 61

Query: 68  RRAVENVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
            +AVE++NK I P L+   + V  Q +ID+++IE+DGTENKS  GANAIL VSLAV+ A 
Sbjct: 62  LKAVEHINKTIGPALIEKKISVVEQEKIDKVVIEMDGTENKSKFGANAILGVSLAVSHAG 121

Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182
           A    +PLY++   L G    +LPVP  NVINGG HAGN L  QEFM++P+GA SF +A+
Sbjct: 122 AAEKGVPLYRHIADLAGNTELILPVPAFNVINGGSHAGNKLAMQEFMVLPVGAASFHDAM 181

Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242
           R  +E YH LK VI  KYGK+A NVGDEGGFAP + +  E L++L  AI +AGY   +++
Sbjct: 182 RVGAEVYHSLKGVIKAKYGKDATNVGDEGGFAPNILDNHEALELLKAAIAQAGYT--DKV 239

Query: 243 ALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEED 295
            + +D A+SEF +DG+Y +  K         T E+L E+Y+     YP+VSIEDPF ++D
Sbjct: 240 VIGMDVAASEFCRDGRYDLDFKSPPDPKRLITGEQLGEIYRGFIKDYPVVSIEDPFDQDD 299

Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355
           WE +      +   +Q+VGDDL V NPKR+    E  A N LLL VNQIG++TE++ A  
Sbjct: 300 WEAWKRFVSHVD--IQVVGDDLTVANPKRIAHAAEQHACNCLLLGVNQIGSVTESIQACK 357

Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415
           +A   G+GV+VSHRSGETED  IADL V L  GQI+ GAP RS+R AKYNQL+RIEE L 
Sbjct: 358 LAQSHGWGVMVSHRSGETEDTFIADLVVGLCTGQIEQGAPCRSERLAKYNQLMRIEEALG 417

Query: 416 GVAVYAGKNFR 426
             A +AG+ FR
Sbjct: 418 DKAKFAGRKFR 428


>sp|P75189|ENO_MYCPN ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|2146503|pir||S73562 phosphopyruvate
           hydratase (EC 4.2.1.11) - Mycoplasma pneumoniae (strain
           ATCC 29342) >gi|1673903|gb|AAB95884.1| (AE000023)
           enolase (eno) [Mycoplasma pneumoniae]
           Length = 456
           
 Score =  421 bits (1072), Expect = e-117
 Identities = 233/439 (53%), Positives = 308/439 (70%), Gaps = 23/439 (5%)

Query: 7   YEIVAVIAREILDSRGNPTVEVDVHTPIS-MGRAAVPSGASTGTHEAVELRDGG-KRYHG 64
           ++I  + A ++ DSRG PTV   V       G A VPSGASTG  EA+ELRDG  K Y G
Sbjct: 10  FKIADLFAYQVFDSRGFPTVACVVKLASGHTGEAMVPSGASTGEKEAIELRDGDPKAYFG 69

Query: 65  KGVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKA 124
           KGV +AV+NVN+ IAP+L+G++   Q  ID L+I+LDGT NK+ LGANAILAVSLAVAKA
Sbjct: 70  KGVSQAVQNVNQTIAPKLIGLNATDQAAIDALMIQLDGTPNKAKLGANAILAVSLAVAKA 129

Query: 125 AANALELPLYQYLG----GVNA--YVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSF 178
           AA+A +  L++YL     G+N   ++L VP+ NVINGG HA N++DFQEFMIMP+GANS 
Sbjct: 130 AASAQKTSLFKYLANQVMGLNKTEFILTVPMLNVINGGAHADNNIDFQEFMIMPLGANSM 189

Query: 179 REAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKP 238
            +A++  SET+H L+K++ ++ G N  N GDEGGFAP +K   E LD++++AI+ AGY+P
Sbjct: 190 HQALKMASETFHALQKLLKQR-GLNT-NKGDEGGFAPNLKLAEEALDLMVEAIKAAGYQP 247

Query: 239 GEEIALALDAASSEFYKDG--KY---------IVSGKEY--TREELLELYKELTSTYPIV 285
           G +IA+ALD A+SEFY D   +Y         I+  KE+  T  +++   K+LT  YPI+
Sbjct: 248 GSDIAIALDVAASEFYDDTTKRYVFKKGIKAKILDEKEWSLTTAQMIAYLKKLTEQYPII 307

Query: 286 SIEDPFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIG 345
           SIED   E DWEG   +T+ LG+ +QIVGDDL+ TNP   +KG+   A N++L+K+NQIG
Sbjct: 308 SIEDGLSEHDWEGMETLTKTLGQHIQIVGDDLYCTNPAIAEKGVAHKATNSILIKLNQIG 367

Query: 346 TLTEAMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYN 405
           TLTE + A  +A  A +  V+SHRSGETED TIADLAVA   GQIKTG+ +RS+R AKYN
Sbjct: 368 TLTETIKAINIAKDANWSQVISHRSGETEDTTIADLAVAACTGQIKTGSMSRSERIAKYN 427

Query: 406 QLIRIEEELEGVAVYAGKN 424
           +L++IE EL   A Y G N
Sbjct: 428 RLLQIELELGNNAKYLGWN 446


>pir||E81654 enolase TC0876 [imported] - Chlamydia muridarum (strain Nigg)
           >gi|7190904|gb|AAF39672.1| (AE002354) enolase [Chlamydia
           muridarum]
           Length = 424
           
 Score =  419 bits (1066), Expect = e-116
 Identities = 228/413 (55%), Positives = 287/413 (69%), Gaps = 6/413 (1%)

Query: 14  AREILDSRGNPTVEVDVHTPISM-GRAAVPSGASTGTHEAVELRDGG-KRYHGKGVRRAV 71
           AREILDSRG PT+ V V T   + G A VPSGASTG  EA+ELRD   KRY GKGV +AV
Sbjct: 11  AREILDSRGYPTLYVKVITNTGIFGEACVPSGASTGIKEALELRDQDPKRYQGKGVLQAV 70

Query: 72  ENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANALEL 131
            NV K++ P L G  V  Q   D ++I+ DGT NK  LGANAIL VSLA+AKAAA  LE 
Sbjct: 71  ANVEKVLLPALQGFSVFDQITADAIMIDADGTSNKEKLGANAILGVSLALAKAAAATLER 130

Query: 132 PLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVSETYHV 191
           PLY+YLGG  ++VLP P+ N+INGG+HA N L FQEFMI PI A S  EA+R  +E +H 
Sbjct: 131 PLYRYLGGAFSHVLPCPMMNLINGGMHATNGLQFQEFMIRPISAPSLTEAVRMGAEVFHT 190

Query: 192 LKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALALDAASS 251
           LKK++  +  + +  VGDEGGFAP +   +E LD+L+ AIE+AG+ PGE+I+LALD A+S
Sbjct: 191 LKKILQNR--QLSTGVGDEGGFAPQLASNSEALDLLLAAIEKAGFIPGEDISLALDCAAS 248

Query: 252 EFYKDGKYIVSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMITRELGKKVQ 311
            FY        GK  +  + + +  EL   YPI SIED   EED+EG+ +++  LG ++Q
Sbjct: 249 SFYNTQDKTYDGK--SAADQVAVLTELCDRYPIDSIEDGLAEEDFEGWKLLSETLGDRIQ 306

Query: 312 IVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYGVVVSHRSG 371
           +VGDDLFVTN   + +GI  G ANA+L+K NQIGTLTE  +A  +A   GY  ++SHRSG
Sbjct: 307 LVGDDLFVTNSALIAEGIAQGLANAVLIKPNQIGTLTETAEAIRLATTQGYATILSHRSG 366

Query: 372 ETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAGKN 424
           ETED TIADLAVA N GQIKTG+ +RS+R AKYN+LI IEEE+   AV+   N
Sbjct: 367 ETEDTTIADLAVAFNTGQIKTGSLSRSERIAKYNRLIAIEEEIGPEAVFQDSN 419


>sp|Q9Z7A6|ENO_CHLPN ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|7436889|pir||A72034 enolase -
           Chlamydophila pneumoniae (strain CWL029)
           >gi|4377111|gb|AAD18938.1| (AE001661) Enolase
           [Chlamydophila pneumoniae CWL029]
           Length = 428
           
 Score =  417 bits (1061), Expect = e-115
 Identities = 230/420 (54%), Positives = 294/420 (69%), Gaps = 10/420 (2%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRD-GGKRYHGKG 66
           I  + AREILDSRG PT+ V V T   S+G A VPSGASTG  EA+E RD    RY GKG
Sbjct: 6   IADIQAREILDSRGYPTLHVKVTTSTGSVGEARVPSGASTGKKEALEFRDTDSPRYQGKG 65

Query: 67  VRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAA 126
           V +AV+NV +I+ P + G  V  Q  ID L+++ DG+ NK  LGANAIL VSLA A AAA
Sbjct: 66  VLQAVKNVKEILFPLVKGCSVYEQSLIDSLMMDSDGSPNKETLGANAILGVSLATAHAAA 125

Query: 127 NALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVS 186
             L  PLY+YLGG  A  LP P+ N+INGG+HA N L+FQEFMI PIGA+S +EA+   +
Sbjct: 126 ATLRRPLYRYLGGCFACSLPCPMMNLINGGMHADNGLEFQEFMIRPIGASSIKEAVNMGA 185

Query: 187 ETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALAL 246
           + +H LKK++ E+    +  VGDEGGFAP +    E L++L+ AIE+AG+ PG++I+LAL
Sbjct: 186 DVFHTLKKLLHER--GLSTGVGDEGGFAPNLASNEEALELLLLAIEKAGFTPGKDISLAL 243

Query: 247 DAASSEFY--KDGKYIVSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMITR 304
           D A+S FY  K G Y   G+ Y  EE + +   L   YPI SIED   EED++G+ ++T 
Sbjct: 244 DCAASSFYNVKTGTY--DGRHY--EEQIAILSNLCDRYPIDSIEDGLAEEDYDGWALLTE 299

Query: 305 ELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYGV 364
            LG+KVQIVGDDLFVTNP+ + +GI  G AN++L+K NQIGTLTE + A  +A  AGY  
Sbjct: 300 VLGEKVQIVGDDLFVTNPELILEGISNGLANSVLIKPNQIGTLTETVYAIKLAQMAGYTT 359

Query: 365 VVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAGKN 424
           ++SHRSGET D TIADLAVA NAGQIKTG+ +RS+R AKYN+L+ IEEEL   A++   N
Sbjct: 360 IISHRSGETTDTTIADLAVAFNAGQIKTGSLSRSERVAKYNRLMEIEEELGSEAIFTDSN 419


>gi|6323985 Ymr323wp [Saccharomyces cerevisiae]
           >gi|1706698|sp|P42222|ERR1_YEAST ENOLASE RELATED PROTEIN
           1 >gi|2118301|pir||S69881 phosphopyruvate hydratase (EC
           4.2.1.11) YMR323w - yeast  (Saccharomyces cerevisiae)
           >gi|1072413|emb|CAA90841.1| (Z54141) unknown
           [Saccharomyces cerevisiae]
           Length = 437
           
 Score =  416 bits (1058), Expect = e-115
 Identities = 229/433 (52%), Positives = 289/433 (65%), Gaps = 20/433 (4%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67
           I  V AR + DSRGNPTVEV++ T   + RA VPSGASTG HEAVELRDG K  + GKGV
Sbjct: 3   ITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGV 62

Query: 68  RRAVENVNKIIAPELVGMD--VRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
            +AV NVN II P L+  D  V  Q+ ID L+I LDGT NKS LGANAIL VSL VA+AA
Sbjct: 63  TKAVSNVNSIIGPALIKSDLCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAA 122

Query: 126 ANALELPLYQYLGGV-----NAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFRE 180
           A    + LY+Y+  +     + +V+PVP  NV+NGG HAG  L  QEF I P+GA SF E
Sbjct: 123 AAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQSFAE 182

Query: 181 AIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGE 240
           A+R  SE YH LK +  E+YG +A NVGDEGG AP +    + LD+++KAI   GY+   
Sbjct: 183 AMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVKAINICGYEG-- 240

Query: 241 EIALALDAASSEFYKDGKYIVSGKEYTRE--------ELLELYKELTSTYPIVSIEDPFH 292
            + + +D+A S FYKDGKY ++ KE   +        +L E Y  L   YPI+S+EDP+ 
Sbjct: 241 RVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLEDPYA 300

Query: 293 EEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMD 352
           E+DW  +    + +   VQI+ DDL  TN  R+ + IE   AN LLLK+NQIGTLTE+++
Sbjct: 301 EDDWSSWSAFLKTVN--VQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIE 358

Query: 353 AAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEE 412
           AA  AF AG+GV++SHRSGETED  IADL V L  GQIK+GA +RS+R AKYN+L+RIEE
Sbjct: 359 AANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEE 418

Query: 413 ELEGVAVYAGKNF 425
           EL    +YAG  F
Sbjct: 419 ELGDDCIYAGHRF 431


>pir||G81504 enolase CP1071 [imported] - Chlamydophila pneumoniae (strain AR39)
           >gi|7189985|gb|AAF38843.1| (AE002264) enolase
           [Chlamydophila pneumoniae AR39]
           >gi|8979174|dbj|BAA99008.1| (AP002548) enolase
           [Chlamydophila pneumoniae J138]
           Length = 428
           
 Score =  416 bits (1058), Expect = e-115
 Identities = 230/420 (54%), Positives = 293/420 (69%), Gaps = 10/420 (2%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRD-GGKRYHGKG 66
           I  + AREILDSRG PT+ V V T   S+G A VPSGASTG  EA+E RD    RY GKG
Sbjct: 6   IADIQAREILDSRGYPTLHVKVTTSTGSVGEARVPSGASTGKKEALEFRDTDSPRYQGKG 65

Query: 67  VRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAA 126
           V +AV+NV +I+ P + G  V  Q  ID L+++ DG+ NK  LGANAIL VSLA A AAA
Sbjct: 66  VLQAVKNVKEILFPLVKGCSVYEQSLIDSLMMDSDGSPNKETLGANAILGVSLATAHAAA 125

Query: 127 NALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVS 186
             L  PLY+YLGG  A  LP P+ N+INGG+HA N L FQEFMI PIGA+S +EA+   +
Sbjct: 126 ATLRRPLYRYLGGCFACSLPCPMMNLINGGMHADNGLGFQEFMIRPIGASSIKEAVNMGA 185

Query: 187 ETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALAL 246
           + +H LKK++ E+    +  VGDEGGFAP +    E L++L+ AIE+AG+ PG++I+LAL
Sbjct: 186 DVFHTLKKLLHER--GLSTGVGDEGGFAPNLASNEEALELLLLAIEKAGFTPGKDISLAL 243

Query: 247 DAASSEFY--KDGKYIVSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMITR 304
           D A+S FY  K G Y   G+ Y  EE + +   L   YPI SIED   EED++G+ ++T 
Sbjct: 244 DCAASSFYNVKTGTY--DGRHY--EEQIAILSNLCDRYPIDSIEDGLAEEDYDGWALLTE 299

Query: 305 ELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYGV 364
            LG+KVQIVGDDLFVTNP+ + +GI  G AN++L+K NQIGTLTE + A  +A  AGY  
Sbjct: 300 VLGEKVQIVGDDLFVTNPELILEGISNGLANSVLIKPNQIGTLTETVYAIKLAQMAGYTT 359

Query: 365 VVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAGKN 424
           ++SHRSGET D TIADLAVA NAGQIKTG+ +RS+R AKYN+L+ IEEEL   A++   N
Sbjct: 360 IISHRSGETTDTTIADLAVAFNAGQIKTGSLSRSERVAKYNRLMEIEEELGSEAIFTDSN 419


>sp|O84591|ENO_CHLTR ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|7436872|pir||D71496 probable enolase -
           Chlamydia trachomatis (serotype D, strain UW3/Cx)
           >gi|3329030|gb|AAC68189.1| (AE001329) Enolase [Chlamydia
           trachomatis]
           Length = 424
           
 Score =  414 bits (1052), Expect = e-114
 Identities = 226/413 (54%), Positives = 285/413 (68%), Gaps = 6/413 (1%)

Query: 14  AREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRDGG-KRYHGKGVRRAV 71
           AREILDSRG PT+ V V T   + G A VPSGASTG  EA+ELRD   KRY GKGV +A+
Sbjct: 11  AREILDSRGYPTLCVKVITNTGTFGEACVPSGASTGIKEALELRDKDPKRYQGKGVLQAI 70

Query: 72  ENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANALEL 131
            NV K++ P L G  V  Q   D ++I+ DGT NK  LGANAIL VSLA+AKAAAN L+ 
Sbjct: 71  SNVEKVLMPALQGFSVFDQITADAIMIDADGTPNKEKLGANAILGVSLALAKAAANTLQR 130

Query: 132 PLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVSETYHV 191
           PLY+YLGG  ++VLP P+ N+INGG+HA N L FQEFMI PI A S  EA+R  +E ++ 
Sbjct: 131 PLYRYLGGSFSHVLPCPMMNLINGGMHATNGLQFQEFMIRPISAPSLTEAVRMGAEVFNA 190

Query: 192 LKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALALDAASS 251
           LKK++  +  + A  VGDEGGFAP +    E LD+L+ AIE AG+ P E+I+LALD A+S
Sbjct: 191 LKKILQNR--QLATGVGDEGGFAPNLASNAEALDLLLTAIETAGFTPREDISLALDCAAS 248

Query: 252 EFYKDGKYIVSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMITRELGKKVQ 311
            FY        GK Y  +  + +  EL   YPI SIED   EED+EG+ +++  LG +VQ
Sbjct: 249 SFYNTQDKTYDGKSYADQ--VGILAELCEHYPIDSIEDGLAEEDFEGWKLLSETLGDRVQ 306

Query: 312 IVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYGVVVSHRSG 371
           +VGDDLFVTN   + +GI  G ANA+L+K NQIGTLTE  +A  +A   GY  ++SHRSG
Sbjct: 307 LVGDDLFVTNSALIAEGIAQGLANAVLIKPNQIGTLTETAEAIRLATIQGYATILSHRSG 366

Query: 372 ETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAGKN 424
           ETED TIADLAVA N GQIKTG+ +RS+R AKYN+L+ IEEE+   A++   N
Sbjct: 367 ETEDTTIADLAVAFNTGQIKTGSLSRSERIAKYNRLMAIEEEMGPEALFQDSN 419


>gi|6324969 enolase homolog; Err1p [Saccharomyces cerevisiae]
           >gi|6324974|ref|NP_015042.1| Similar to enolase; Err2p
           [Saccharomyces cerevisiae] >gi|2118299|pir||S67305
           phosphopyruvate hydratase (EC 4.2.1.11) ERR1 - yeast
           (Saccharomyces cerevisiae) >gi|1370578|emb|CAA98018.1|
           (Z73637) ORF YPL281c [Saccharomyces cerevisiae]
           >gi|1420845|emb|CAA99725.1| (Z75301) ORF YOR393w
           [Saccharomyces cerevisiae]
           Length = 437
           
 Score =  413 bits (1050), Expect = e-114
 Identities = 227/433 (52%), Positives = 289/433 (66%), Gaps = 20/433 (4%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67
           I  V AR + DSRGNPTVEV++ T   + RA VPSGASTG HEAVELRDG K  + GKGV
Sbjct: 3   ITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGV 62

Query: 68  RRAVENVNKIIAPELVGMD--VRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
            +AV NVN II P L+  +  V  Q+ ID L+I LDGT NKS LGANAIL VSL VA+AA
Sbjct: 63  TKAVSNVNSIIGPALIKSELCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAA 122

Query: 126 ANALELPLYQYLGGV-----NAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFRE 180
           A    + LY+Y+  +     + +V+PVP  NV+NGG HAG  L  QEF I P+GA SF E
Sbjct: 123 AAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQSFAE 182

Query: 181 AIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGE 240
           A+R  SE YH LK +  E+YG +A NVGDEGG AP +    + LD++++AI   GY+   
Sbjct: 183 AMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVEAINICGYEG-- 240

Query: 241 EIALALDAASSEFYKDGKYIVSGKEYTRE--------ELLELYKELTSTYPIVSIEDPFH 292
            + + +D+A S FYKDGKY ++ KE   +        +L E Y  L   YPI+S+EDP+ 
Sbjct: 241 RVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLEDPYA 300

Query: 293 EEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMD 352
           E+DW  +    + +   VQI+ DDL  TN  R+ + IE   AN LLLK+NQIGTLTE+++
Sbjct: 301 EDDWSSWSAFLKTVN--VQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIE 358

Query: 353 AAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEE 412
           AA  AF AG+GV++SHRSGETED  IADL V L  GQIK+GA +RS+R AKYN+L+RIEE
Sbjct: 359 AANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEE 418

Query: 413 ELEGVAVYAGKNF 425
           EL    +YAG  F
Sbjct: 419 ELGDDCIYAGHRF 431


>sp|P57492|ENO_BUCAI ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|10039081|dbj|BAB13115.1| (AP001119)
           enolase [Buchnera sp. APS]
           Length = 434
           
 Score =  411 bits (1045), Expect = e-114
 Identities = 220/417 (52%), Positives = 299/417 (70%), Gaps = 12/417 (2%)

Query: 8   EIVAVIAREILDSRGNPTVEVDVHTPIS-MGRAAVPSGASTGTHEAVELRDGGK-RYHGK 65
           +I  +IAREI+DSRGNPTVE +VH     +G A+ PSGASTG+ EA+ELRD  K R+ GK
Sbjct: 3   KITKIIAREIIDSRGNPTVESEVHLEGGFVGLASSPSGASTGSLEALELRDENKDRFMGK 62

Query: 66  GVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
           GV +AV  +N+ I+  L   + R Q +ID ++I+LDGT NKS LGANAIL+VSLAVAKAA
Sbjct: 63  GVEKAVSLINEKISIALKNKNARNQSDIDHIMIDLDGTINKSKLGANAILSVSLAVAKAA 122

Query: 126 ANALELPLYQYLGGVN----AYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREA 181
           A +  +PLY ++  +N     + +P+P+ N+INGG HA N++D QEFMI PI A + +E+
Sbjct: 123 AASKRMPLYAHIAEINETPGVFSMPLPMINIINGGKHANNNIDIQEFMIQPISAKTVKES 182

Query: 182 IRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEE 241
           IR   E +H L +++ EK    +  VGDEGG+AP +K   E L+++  AI++  YK G++
Sbjct: 183 IRIGCEIFHALGELLKEK--GMSTTVGDEGGYAPNLKSNEEALNIIQDAIQKTKYKLGQD 240

Query: 242 IALALDAASSEFYK--DGKYIVSGKE--YTREELLELYKELTSTYPIVSIEDPFHEEDWE 297
           I LA+D A+SE Y   + KY + G+   ++ +E     ++L+  YPIVSIED   E DWE
Sbjct: 241 IRLAIDCAASELYNKNEKKYNLKGENISFSSKEFTHYLEKLSQKYPIVSIEDGQDESDWE 300

Query: 298 GFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMA 357
           GF+  T  LG K+Q+VGDDLFVTN   LKKGI+ G AN++L+K+NQIGTLTE ++A   A
Sbjct: 301 GFLYQTHVLGNKIQLVGDDLFVTNKNILKKGIKKGIANSILIKLNQIGTLTETLEAIKTA 360

Query: 358 FRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEEL 414
            +A YGV++SHRSGETEDA+IADL+V  ++GQIKTG+ +RSDR +KYNQLIRIEE L
Sbjct: 361 KQANYGVIISHRSGETEDASIADLSVGTSSGQIKTGSMSRSDRTSKYNQLIRIEENL 417


>dbj|BAA88483.1| (AB025330) enolase-2 [Lampetra reissneri]
           Length = 395
           
 Score =  408 bits (1038), Expect = e-113
 Identities = 223/394 (56%), Positives = 280/394 (70%), Gaps = 17/394 (4%)

Query: 46  STGTHEAVELRDGGK-RYHGKGVRRAVENVNKIIAPELVGMD--VRWQREIDRLLIELDG 102
           STG +EA+ELRDG K RY GKGV +AV ++NK IAP L+  +  V  Q +ID  ++ELDG
Sbjct: 1   STGIYEALELRDGDKSRYLGKGVLKAVNHINKEIAPALIAKNFSVVDQEKIDNFMLELDG 60

Query: 103 TENKSNLGANAILAVSLAVAKAAANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHA 159
           TENKS  GANAIL VSLAV KAAA    +PLY++   L G    +LPVP  NVINGG HA
Sbjct: 61  TENKSKFGANAILGVSLAVCKAAAAEKGVPLYRHIADLAGHKEVILPVPAFNVINGGSHA 120

Query: 160 GNDLDFQEFMIMPIGANSFREAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKE 219
           GN L  QEFMI+P+GA+SF EA+R  +E YH LK VI EKYGK+A NVGDEGGFAP + E
Sbjct: 121 GNKLAMQEFMILPVGASSFHEALRIGAEVYHNLKGVIKEKYGKDATNVGDEGGFAPNILE 180

Query: 220 VTEPLDVLIKAIEEAGYKPGEEIALALDAASSEFYKDGKYIVSGKE-------YTREELL 272
             E L++L  AI +AGY   ++I + +D A+SEFY+ G Y +  K         T ++L 
Sbjct: 181 NKEALELLKTAINKAGYS--DKIVIGMDVAASEFYRKGMYDLDFKSPDDPKRYITPDKLA 238

Query: 273 ELYKELTSTYPIVSIEDPFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMG 332
           ELY+  T  YP+VSIEDPF ++DWE +  IT     K+QIVGDDL VTNPKR++K +++ 
Sbjct: 239 ELYQGFTKDYPVVSIEDPFDQDDWEAWTKITANT--KIQIVGDDLTVTNPKRIQKAVDVK 296

Query: 333 AANALLLKVNQIGTLTEAMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKT 392
           A N LLLKVNQIG++TE++ A  +A   G+GV+VSHRSGETED  IADL V L  GQIKT
Sbjct: 297 ACNCLLLKVNQIGSVTESIKACKLAQNNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKT 356

Query: 393 GAPARSDRNAKYNQLIRIEEELEGVAVYAGKNFR 426
           GAP RS+R +KYNQ++RIEEEL   A +AG +FR
Sbjct: 357 GAPCRSERLSKYNQIMRIEEELGDKAKFAGHSFR 390


>gb|AAB87891.1| (AF025806) enolase [Drosophila subobscura]
           Length = 413
           
 Score =  406 bits (1033), Expect = e-112
 Identities = 221/415 (53%), Positives = 282/415 (67%), Gaps = 18/415 (4%)

Query: 27  EVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRAVENVNKIIAPELV-- 83
           EVD+ T   + RAAVPSGASTG HEA+ELRD  K  YHGK V +AV +VN  + PE++  
Sbjct: 1   EVDLTTEHGLFRAAVPSGASTGVHEALELRDNDKANYHGKSVLKAVAHVNDTLGPEVIKA 60

Query: 84  GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANALELPLYQY---LGGV 140
            +DV  Q  +D  +I+LDGTENKS  GANAIL +SLAVAKA A    +PLY++   L G 
Sbjct: 61  NLDVVDQAAVDNFMIKLDGTENKSKFGANAILGISLAVAKAGAAKKNVPLYKHIADLAGN 120

Query: 141 NAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVSETYHVLKKVIAEKY 200
              +LPVP  NVINGG HAGN L  QEFMI+P GA +F EA++  SE YH LK VI  K+
Sbjct: 121 KEIILPVPAFNVINGGSHAGNKLAMQEFMILPTGATTFTEAMKMGSEVYHHLKNVIKAKF 180

Query: 201 GKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALALDAASSEFYKDGKYI 260
           G +A  VGDEGGFAP ++   E L ++  AI +AGY    +I + +D A+SEF+KDG Y 
Sbjct: 181 GLDATAVGDEGGFAPNIQSNKEALVLITDAIAKAGYTG--KIEIGMDVAASEFFKDGLYD 238

Query: 261 VSGKE--------YTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMITRELGKKVQI 312
           +  K          T ++L  LY+E    +PI SIEDPF ++ W+ +  +T     K+QI
Sbjct: 239 LDFKNPASDKAQWLTPDKLANLYQEFIKEFPITSIEDPFDQDHWDAWTNLTSNT--KIQI 296

Query: 313 VGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYGVVVSHRSGE 372
           VGDDL VTNPKR+   +E GA N LLLKVNQIGT+TE++ A  +A + G+G +VSHRSGE
Sbjct: 297 VGDDLTVTNPKRIATAVEKGACNCLLLKVNQIGTVTESIAAHLLAKKNGWGTMVSHRSGE 356

Query: 373 TEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAGKNFRK 427
           TED+ I DL V L+ GQIKTGAP RS+R AKYNQ++RIEEE+     +AGK+FRK
Sbjct: 357 TEDSFIGDLVVGLSTGQIKTGAPCRSERLAKYNQILRIEEEIGSGVKFAGKSFRK 411


>sp|P47647|ENO_MYCGE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|1361755|pir||A64245 phosphopyruvate
           hydratase (EC 4.2.1.11) - Mycoplasma genitalium
           >gi|3845000|gb|AAC71635.1| (U39723) enolase (eno)
           [Mycoplasma genitalium]
           Length = 458
           
 Score =  403 bits (1024), Expect = e-111
 Identities = 217/438 (49%), Positives = 297/438 (67%), Gaps = 23/438 (5%)

Query: 8   EIVAVIAREILDSRGNPTVEVDVHTPIS-MGRAAVPSGASTGTHEAVELRDGG-KRYHGK 65
           +I  + A ++ DSRG PTV   V      +G A VPSGASTG  EA+ELRD   K Y GK
Sbjct: 11  KITDIFAYQVFDSRGVPTVACVVKLASGHVGEAMVPSGASTGEKEAIELRDNDPKNYFGK 70

Query: 66  GVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
           GV  AV+NVNK+IAP+L+G++   Q  +D+ +I+LD T NK+ LGANAIL+VSLAV+KAA
Sbjct: 71  GVNEAVDNVNKVIAPKLIGLNAFDQLTVDQAMIKLDNTPNKAKLGANAILSVSLAVSKAA 130

Query: 126 ANALELPLYQYLG----GVNA--YVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFR 179
           A A    L+QY+     G+N   +VLPVP+ NVINGG HA N +DFQEFMIMP+GA    
Sbjct: 131 AKAQNSSLFQYISNKLIGLNTTNFVLPVPMLNVINGGAHADNYIDFQEFMIMPLGAKKMH 190

Query: 180 EAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPG 239
           EA++  SET+H L+ ++ +K G N  N GDEGGFAP +K   + LD++++AI+ AGYKP 
Sbjct: 191 EALKMASETFHALQNLL-KKRGLNT-NKGDEGGFAPNLKLAEDALDIMVEAIKLAGYKPW 248

Query: 240 EEIALALDAASSEFYKDGKY-----------IVSGKEY--TREELLELYKELTSTYPIVS 286
           ++IA+A+D A+SEFY + K            I++ K++  T +E++   ++LT  YPI+S
Sbjct: 249 DDIAIAIDVAASEFYDEDKKLYVFKKGIKANILNAKDWSLTSKEMIAYLEKLTKKYPIIS 308

Query: 287 IEDPFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGT 346
           IED   E DWEG   +T+ +G  +QIVGDD + TN +  KKG+     N++L+K+NQIG+
Sbjct: 309 IEDGLSENDWEGMNQLTKTIGSHIQIVGDDTYCTNAELAKKGVAQNTTNSILIKLNQIGS 368

Query: 347 LTEAMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQ 406
           ++E +    +A +A +  V+SHRSGETED TIADLAVA   GQIKTG+ +RS+R AKYN+
Sbjct: 369 ISETIQTIEVAKKANWSQVISHRSGETEDTTIADLAVAAQTGQIKTGSMSRSERIAKYNR 428

Query: 407 LIRIEEELEGVAVYAGKN 424
           L+ IE EL     Y G N
Sbjct: 429 LLYIEIELGDKGKYLGWN 446


>gb|AAB87890.1| (AF025805) enolase [Drosophila pseudoobscura]
           Length = 413
           
 Score =  403 bits (1024), Expect = e-111
 Identities = 219/415 (52%), Positives = 280/415 (66%), Gaps = 18/415 (4%)

Query: 27  EVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRAVENVNKIIAPELV-- 83
           EVD+ T   + RAAVPSGASTG HEA+ELRD  K  YHGK V +AV +VN  + PE++  
Sbjct: 1   EVDLTTENGLFRAAVPSGASTGVHEALELRDNDKANYHGKSVLKAVAHVNDTLGPEVIKA 60

Query: 84  GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANALELPLYQY---LGGV 140
            +DV  Q  +D  +I+LDGTENKS  GANAIL +SLAVAKA A    +PLY++   L G 
Sbjct: 61  NLDVVDQAAVDNFMIKLDGTENKSKFGANAILGISLAVAKAGAAKKNVPLYKHIADLAGN 120

Query: 141 NAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVSETYHVLKKVIAEKY 200
              +LPVP  NVINGG HAGN L  QEFMI+P GA +F EA++  SE YH LK VI  K+
Sbjct: 121 KEIILPVPAFNVINGGSHAGNKLAMQEFMILPTGATTFTEAMKMGSEVYHHLKNVIKAKF 180

Query: 201 GKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALALDAASSEFYKDGKYI 260
           G +A  VGDEGGFAP ++   E L ++  AI +AGY    +I + +D A+SEF+KDG Y 
Sbjct: 181 GLDATAVGDEGGFAPNIQSNKEALVLITDAIAKAGYTG--KIEIGMDVAASEFFKDGLYD 238

Query: 261 VSGKE--------YTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMITRELGKKVQI 312
           +  K          + ++   LY+E    +PI SIEDPF ++ W+ +  +T     K+QI
Sbjct: 239 LDFKNPASDKAQWLSPDKXANLYQEFIKEFPITSIEDPFDQDHWDAWTNLT--CNTKIQI 296

Query: 313 VGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYGVVVSHRSGE 372
           VGDDL VTNPKR+   +E GA N LLLKVNQIGT+TE++ A  +A + G+G +VSHRSGE
Sbjct: 297 VGDDLTVTNPKRIATAVEKGACNCLLLKVNQIGTVTESIAAHLLAKKNGWGTMVSHRSGE 356

Query: 373 TEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAGKNFRK 427
           TED+   DL V L+ GQIKTGAP RS+R AKYNQ++RIEEE+     +AGKNFRK
Sbjct: 357 TEDSFXGDLVVGLSTGQIKTGAPCRSERLAKYNQILRIEEEIGSGVKFAGKNFRK 411


>dbj|BAA88479.1| (AB025326) enolase [Eptatretus burgeri]
           Length = 395
           
 Score =  403 bits (1024), Expect = e-111
 Identities = 216/394 (54%), Positives = 280/394 (70%), Gaps = 17/394 (4%)

Query: 46  STGTHEAVELRDGGK-RYHGKGVRRAVENVNKIIAPELVG--MDVRWQREIDRLLIELDG 102
           STG +EA+ELRDG K RY GKGV +AV ++N  IAP+L+    +V+ Q  ID+ +++LDG
Sbjct: 1   STGIYEALELRDGDKSRYLGKGVLKAVNHINATIAPKLIAKNFNVKDQTAIDKFMLDLDG 60

Query: 103 TENKSNLGANAILAVSLAVAKAAANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHA 159
           TENKS  GANAIL VSLAV KAAA    +PLY++   L G    +LPVP  NVINGG HA
Sbjct: 61  TENKSQFGANAILGVSLAVCKAAAAEKGVPLYRHIADLAGHKDVILPVPAFNVINGGSHA 120

Query: 160 GNDLDFQEFMIMPIGANSFREAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKE 219
           GN L  QEFMI+P+GA +F +A+R  +E YH LK VI +KYGK+A NVGDEGGFAP + +
Sbjct: 121 GNKLAMQEFMILPVGAANFHDAMRIGAEVYHNLKSVIKDKYGKDATNVGDEGGFAPNILD 180

Query: 220 VTEPLDVLIKAIEEAGYKPGEEIALALDAASSEFYKDGKYIVSGKE-------YTREELL 272
             E L++L  AI +AGY   ++I + +D A+SEFY+DGKY +  K         + ++L 
Sbjct: 181 NQEALELLKHAINKAGYT--DKIVIGMDVAASEFYRDGKYDLDFKSPDDPSRHISPDKLA 238

Query: 273 ELYKELTSTYPIVSIEDPFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMG 332
           +LY      YP+VSIEDPF ++ WE +   T      +Q+VGDDL VTNPKR++KG+++ 
Sbjct: 239 DLYHGFIKDYPVVSIEDPFDQDHWEAWTKFTASTD--IQVVGDDLTVTNPKRIQKGVDIK 296

Query: 333 AANALLLKVNQIGTLTEAMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKT 392
           A N LLLKVNQIG++TE++ A  +A   G+GV+VSHRSGETED+ IADL V L  GQIKT
Sbjct: 297 ACNCLLLKVNQIGSVTESIQACKLAQNNGWGVMVSHRSGETEDSFIADLVVGLCTGQIKT 356

Query: 393 GAPARSDRNAKYNQLIRIEEELEGVAVYAGKNFR 426
           GAP RS+R AKYNQ++RIEEEL   A +AGKNFR
Sbjct: 357 GAPCRSERLAKYNQMMRIEEELGSNAKFAGKNFR 390


>gb|AAC95183.1| (AC004561) putative enolase (2-phospho-D-glycerate hydroylase)
           [Arabidopsis thaliana]
           Length = 475
           
 Score =  400 bits (1017), Expect = e-110
 Identities = 220/430 (51%), Positives = 299/430 (69%), Gaps = 16/430 (3%)

Query: 9   IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67
           I  V AR+ILDSRG PTVEVD+HT   + RA+VPSG S+GT+EA+ELRDG K  Y G  V
Sbjct: 47  ITKVKARQILDSRGIPTVEVDLHTNKGVFRASVPSGDSSGTYEAIELRDGDKGMYLGNSV 106

Query: 68  RRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAAN 127
            +AV+N+N+ I+  L+GMD + Q +ID+ +I+LD TE KS LGANAILAVS+A  KA A 
Sbjct: 107 AKAVKNINEKISEALIGMDPKLQGQIDQAMIDLDKTEKKSELGANAILAVSIAACKAGAA 166

Query: 128 ALELPLYQYLGGVNA---YVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRW 184
             E+PL ++L  ++     VLPVP   V++GG HA N    QE MI+PIGA+ F EA++W
Sbjct: 167 EKEVPLCKHLSDLSGRANMVLPVPAFTVLSGGKHASNTFAIQEIMILPIGASRFEEALQW 226

Query: 185 VSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIAL 244
            SETYH LK VI+EK G    NVG++GG AP +  + E L+++ +AI   GY   ++I +
Sbjct: 227 GSETYHHLKAVISEKNGGLGCNVGEDGGLAPDISSLKEGLELVKEAINRTGYN--DKIKI 284

Query: 245 ALDAASSEFYKDGKYIV-------SGKEY-TREELLELYKELTSTYPIVSIEDPFHEEDW 296
           A+D A++ F    KY +       SG+ + + E+++++YKE+ + YPIVSIEDPF +EDW
Sbjct: 285 AIDIAATNFCLGTKYDLDIKSPNKSGQNFKSAEDMIDMYKEICNDYPIVSIEDPFDKEDW 344

Query: 297 EGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYM 356
           E     +  LG   Q+VGDDL ++N KR+++ I+  + NALLLKVNQIGT+TEA++   M
Sbjct: 345 EHTKYFS-SLGI-CQVVGDDLLMSNSKRVERAIQESSCNALLLKVNQIGTVTEAIEVVKM 402

Query: 357 AFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEG 416
           A  A +GVV SHR GETED+ I+DL+V L  G IK GAP R +R  KYNQL+RIEEEL  
Sbjct: 403 ARDAQWGVVTSHRCGETEDSFISDLSVGLATGVIKAGAPCRGERTMKYNQLLRIEEELGD 462

Query: 417 VAVYAGKNFR 426
            AVYAG++++
Sbjct: 463 QAVYAGEDWK 472


>dbj|BAA88482.1| (AB025329) enolase-1 [Lampetra reissneri]
           Length = 394
           
 Score =  400 bits (1016), Expect = e-110
 Identities = 217/394 (55%), Positives = 276/394 (69%), Gaps = 17/394 (4%)

Query: 46  STGTHEAVELRDGGK-RYHGKGVRRAVENVNKIIAPELVGMD--VRWQREIDRLLIELDG 102
           STG +EA+ELRD  K RY GKGV +AV ++N  IAP L+     V  Q  ID+ +++LDG
Sbjct: 1   STGIYEALELRDDDKGRYLGKGVLQAVSHINDTIAPALLSQSFSVVEQEAIDQFMLDLDG 60

Query: 103 TENKSNLGANAILAVSLAVAKAAANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHA 159
           TENKS  GANA+L VSLAV KA A    +PLY++   L G +  +LPVP  NVINGG HA
Sbjct: 61  TENKSKFGANAVLGVSLAVCKAGAGEKGVPLYRHIADLAGNSEVILPVPAFNVINGGSHA 120

Query: 160 GNDLDFQEFMIMPIGANSFREAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKE 219
           GN L  QEFMI+P+GA S  EA+R  +E YH LK VI +KYG++A NVGDEGGFAP + E
Sbjct: 121 GNKLAMQEFMILPVGAESLSEALRMGAEVYHSLKAVIKKKYGQDATNVGDEGGFAPNILE 180

Query: 220 VTEPLDVLIKAIEEAGYKPGEEIALALDAASSEFYKDGKYIVSGKE-------YTREELL 272
             E LD+L +AI +AGY   ++I + +D A+SEFY+DGKY +  K         + +EL 
Sbjct: 181 NMEALDLLTQAIGKAGYT--DKIVIGMDVAASEFYRDGKYDLDFKSPADPDRYISADELA 238

Query: 273 ELYKELTSTYPIVSIEDPFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMG 332
           +LY+   S YP+VSIEDPF ++DWE +   T   G  +QIVGDDL VTNP R++  +++ 
Sbjct: 239 DLYRTFISDYPVVSIEDPFDQDDWEAWSNFTANAG--IQIVGDDLTVTNPARIQTAVDVK 296

Query: 333 AANALLLKVNQIGTLTEAMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKT 392
           A N LLLKVNQIG++TE++ A  +A   G+GV+VSHRSGETED  IADL V L  GQIKT
Sbjct: 297 ACNCLLLKVNQIGSVTESIKACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKT 356

Query: 393 GAPARSDRNAKYNQLIRIEEELEGVAVYAGKNFR 426
           GAP RS+R AKYNQL+RIEEEL   A +AG+NFR
Sbjct: 357 GAPCRSERLAKYNQLMRIEEELGKKAQFAGRNFR 390


>sp|P31683|ENO_CHLRE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|99392|pir||S24996 phosphopyruvate
           hydratase (EC 4.2.1.11) - Chlamydomonas reinhardtii
           >gi|18143|emb|CAA47043.1| (X66412) enolase
           [Chlamydomonas reinhardtii]
           Length = 372
           
 Score =  393 bits (998), Expect = e-108
 Identities = 211/374 (56%), Positives = 269/374 (71%), Gaps = 16/374 (4%)

Query: 67  VRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAA 126
           V +AVEN+N IIAP L GMD   Q EID+ + +LDGT+NK  LGANAILAVS+AV KA A
Sbjct: 1   VTKAVENINAIIAPALKGMDPVKQAEIDQKMKDLDGTDNKGKLGANAILAVSMAVCKAGA 60

Query: 127 NALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIR 183
               +PLY++   L G +  +LPVP  N+INGG HAGN L  QEFMI+P+GA+SF EA+R
Sbjct: 61  AEKGVPLYKHIADLAGNSKLILPVPSFNIINGGSHAGNALAMQEFMILPVGASSFSEAMR 120

Query: 184 WVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIA 243
              E YH LK +I  KYG++A NVGDEGGFAP +    E L+++ +AIE+AGY    ++ 
Sbjct: 121 MGCEVYHALKGLIKAKYGQDACNVGDEGGFAPNIGSNDEGLNLVNEAIEKAGYTG--KVK 178

Query: 244 LALDAASSEFY-KDGKYIVSGKEY--------TREELLELYKELTSTYPIVSIEDPFHEE 294
           + +D ASSEFY +DG Y +  K          T+E++LELY E    YP++SIEDPF ++
Sbjct: 179 IGMDVASSEFYTEDGMYDLDFKNQPNDGSQKKTKEQMLELYNEFCKKYPVISIEDPFEQD 238

Query: 295 DWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAA 354
           DWE    +T E     Q+VGDD+ VTNP R+KK I+  A NALLLKVNQIGT+TE+++A 
Sbjct: 239 DWEPCAKLTTE--NICQVVGDDILVTNPVRVKKAIDAKAVNALLLKVNQIGTITESIEAV 296

Query: 355 YMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEEL 414
            MA  AG+GV+ SHRSGETED+ IADLAV L +GQIKTGAP RS+RNAKYNQL+RIEEEL
Sbjct: 297 RMAKEAGWGVMTSHRSGETEDSFIADLAVGLASGQIKTGAPCRSERNAKYNQLLRIEEEL 356

Query: 415 EGVAVYAGKNFRKV 428
              AVYAG+++R +
Sbjct: 357 GENAVYAGESWRHI 370


>gb|AAA49217.1| (M55143) alpha-enolase/tau-crystallin [Anas platyrhynchos]
           Length = 377
           
 Score =  388 bits (986), Expect = e-107
 Identities = 208/375 (55%), Positives = 265/375 (70%), Gaps = 16/375 (4%)

Query: 64  GKGVRRAVENVNKIIAPELVGMDVRW--QREIDRLLIELDGTENKSNLGANAILAVSLAV 121
           GKGV +AVE++NK IAP L+  +V    Q +ID+L++++DG+ENKS  GANAIL VSLAV
Sbjct: 2   GKGVSKAVEHINKTIAPALISKNVNVVEQDKIDKLMLDMDGSENKSKFGANAILGVSLAV 61

Query: 122 AKAAANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSF 178
            KA A    +PLY++   L G    +LPVP  NVINGG HAGN L  QEFMI P GA+SF
Sbjct: 62  CKAGAAEKGVPLYRHIADLAGNPEVILPVPAFNVINGGSHAGNKLAMQEFMIPPCGADSF 121

Query: 179 REAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKP 238
           +EA+R  +E YH LK VI EKYGK+A NVGDEGGFAP + E  E L++L  AI +AGY  
Sbjct: 122 KEAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKTAIGKAGYS- 180

Query: 239 GEEIALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPF 291
            +++ + +D A+SEFY+DGKY +  K         + ++L +LYK     YP+VSIEDPF
Sbjct: 181 -DKVVIGMDVAASEFYRDGKYDLDFKSPDDPSRYISPDQLADLYKGFVKNYPVVSIEDPF 239

Query: 292 HEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAM 351
            ++DW  +   T  +G  +Q+VGDDL VTNPKR+ K +E  A N LLLKVNQIG++TE++
Sbjct: 240 DQDDWGAWKKFTGSVG--IQVVGDDLTVTNPKRIAKAVEEKACNCLLLKVNQIGSVTESL 297

Query: 352 DAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIE 411
            A  +A   G+GV+VSHRSGETED  IADL V L  GQIKTGAP RS+R AKYNQL+RIE
Sbjct: 298 QACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIE 357

Query: 412 EELEGVAVYAGKNFR 426
           EEL   A +AG+NFR
Sbjct: 358 EELGSKARFAGRNFR 372


>gb|AAA37554.1| (M20745) muscle-specific enolase beta subunit (EC 4.2.1.11) [Mus
           musculus]
           Length = 376
           
 Score =  374 bits (951), Expect = e-103
 Identities = 205/375 (54%), Positives = 259/375 (68%), Gaps = 16/375 (4%)

Query: 64  GKGVRRAVENVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAV 121
           GKGV +AVE++NK + P L+   + V  Q ++D+ +IELDGTENKS  GANAIL VSLAV
Sbjct: 1   GKGVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAV 60

Query: 122 AKAAANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSF 178
            KA A    +PLY++   L G    VLPVP  NVINGG HAGN L  QEFMI+P+GA+SF
Sbjct: 61  CKAGAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSF 120

Query: 179 REAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKP 238
           +EA+R  +E YH LK VI  KYGK+A NVGDEGGFAP + E  E L++L  AI+   Y  
Sbjct: 121 KEAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQANAYP- 179

Query: 239 GEEIALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPF 291
            +++ + +D A+SEFY++GKY +  K         + E+L ELYK     YP+VSIEDPF
Sbjct: 180 -DKVVIGMDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGELYKNFIQNYPVVSIEDPF 238

Query: 292 HEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAM 351
            ++DW  +       G  +QIVGDDL VTNPKR+ + +E  A N LLLKVNQIG++TE++
Sbjct: 239 DQDDWATWTSFLS--GVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESI 296

Query: 352 DAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIE 411
            A  +A   G+GV+VSHRSGETED  IADL V L  GQIKTGAP RS+R AKYNQL+RIE
Sbjct: 297 QACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIE 356

Query: 412 EELEGVAVYAGKNFR 426
           E L   AV+AG+ FR
Sbjct: 357 EALGDKAVFAGRKFR 371


>pir||H82922 enolase UU184 [imported] - Ureaplasma urealyticum
           >gi|6899148|gb|AAF30591.1|AE002118_1 (AE002118) enolase
           [Ureaplasma urealyticum]
           Length = 440
           
 Score =  369 bits (936), Expect = e-101
 Identities = 206/441 (46%), Positives = 280/441 (62%), Gaps = 25/441 (5%)

Query: 8   EIVAVIAREILDSRGNPTVEVDVHTPISMGRAA-VPSGASTGTHEAVELRDGGKRYH-GK 65
           +I+ ++A +ILDSRG PTV V +         A VPSGASTG  EA+ELRDG   Y   K
Sbjct: 2   KIINLLAYQILDSRGQPTVAVKLFLENDQSVIAMVPSGASTGAKEALELRDGDVNYFFNK 61

Query: 66  GVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
            V+ A++N+N II P L+  +V    E+D LLI LDGTENKS LGANA+L VS+A+ KA 
Sbjct: 62  SVKLAIQNINNIIRPHLINKNVLNFFELDNLLINLDGTENKSKLGANALLGVSIAIVKAG 121

Query: 126 ANALELPLYQYLG-------GVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSF 178
           A A   PLYQY+         VN Y  P+PL N INGG HA NDLD QEFMI+P+ A SF
Sbjct: 122 AIAASKPLYQYIKEDLMHNYDVNYYA-PIPLMNFINGGAHADNDLDIQEFMIVPLNAISF 180

Query: 179 REAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKP 238
            +AI+  SE +H L K++  K    +   GDEGGFAP +K     L++L+ AI++A Y P
Sbjct: 181 SQAIQIGSEIFHQLDKLL--KSNHLSTTKGDEGGFAPMLKNNYVTLELLVHAIKKAHYLP 238

Query: 239 GEE--IALALDAASSEFYKDGKYI----------VSGKEYTREELLELYKELTSTYPIVS 286
            +   + LALD A+SE Y++GKY           +    ++ +E ++ + +L S +PI+S
Sbjct: 239 SKTQGVCLALDVAASELYENGKYFFKKSSSHNITLEQTSFSSDEWIKYWSKLVSMFPIIS 298

Query: 287 IEDPFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGT 346
           IED F E DW  F +  +     +Q+VGDDL+ TN K L+KGI+  A NA+L+K NQIGT
Sbjct: 299 IEDCFEENDWNSFALFLKN-NPHIQVVGDDLYCTNLKYLQKGIDFKATNAILIKPNQIGT 357

Query: 347 LTEAMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQ 406
           ++E +D    A +     ++SHRSGETED  IADLA+ + AGQIKTG+ +RS+R AKYN+
Sbjct: 358 ISETLDVIKFAQKNNINTIISHRSGETEDTFIADLAIGVGAGQIKTGSLSRSERIAKYNR 417

Query: 407 LIRIEEELEGVAVYAGKNFRK 427
           ++ IE+EL+   +Y    F K
Sbjct: 418 ILEIEQELKDKLIYEPSKFFK 438


>gi|7657062 enolase alpha, lung-specific [Homo sapiens]
           >gi|729422|sp|Q05524|ENOL_HUMAN ALPHA ENOLASE, LUNG
           SPECIFIC (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (NON-NEURAL
           ENOLASE) (NNE) (PHOSPHOPYRUVATE HYDRATASE)
           >gi|105931|pir||S22071 phosphopyruvate hydratase (EC
           4.2.1.11) - human >gi|2135922|pir||I37360
           phosphopyruvate hydratase (EC 4.2.1.11), lung - human
           >gi|31179|emb|CAA47179.1| (X66610) enolase [Homo
           sapiens]
           Length = 458
           
 Score =  363 bits (923), Expect = 2e-99
 Identities = 229/447 (51%), Positives = 296/447 (65%), Gaps = 36/447 (8%)

Query: 14  AREILDSRGNPTVEVDVHTPIS--MGRAAVPSGASTGTHEAV-ELRDGGKRYH--GKGVR 68
           AR+I +SRGNPTVEVD++T      GRAAVPSGASTG +EA+ ELRD  K  +  GKGV 
Sbjct: 9   ARDIFESRGNPTVEVDLYTNKGGLFGRAAVPSGASTGIYEALLELRDNDKTRYMGGKGVS 68

Query: 69  RAVENV-NKIIAPELVGMDVRW--QREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
           +AVE++ NK IAP L+  +V    Q +ID L++++DG+ENKS  GANAIL VSLAV   A
Sbjct: 69  KAVEHIINKTIAPALISKNVNVVEQDKIDNLMLDMDGSENKSKFGANAILGVSLAVCSNA 128

Query: 126 ANALE--LPLYQYL----GGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFR 179
               E  +PLY+++    G     +LPVP  NVINGG HAGN L  QEFMI P GA+ F 
Sbjct: 129 GATAEKGVPLYRHIADLAGNNPEVILPVPAFNVINGGSHAGNKLAMQEFMIPPCGADRFN 188

Query: 180 EAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPG 239
           +AIR  +E YH LK VI EKYGK+A NVGDEGGFAP + E  E L++L  AI +AGY   
Sbjct: 189 DAIRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKTAIGKAGY--S 246

Query: 240 EEIALALDAASSEFYKDGKYIVS-------GKEYTREELLELYK-----ELTSTYPI-VS 286
           +++ + +D A+SEFY+DGKY +         +  + ++L +LYK          YP+ VS
Sbjct: 247 DKVVIGMDVAASEFYRDGKYDLDFNSPDDPSRYISPDQLADLYKGFVLGHAVKNYPVGVS 306

Query: 287 IED-PFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPK-RLKKGI-EMGAANA-LLLKVN 342
           IED PF ++DW  +  +       +Q+VGDDL VT P+ R+ K + E+ A N  LLLKVN
Sbjct: 307 IEDPPFDQDDWGAWKKLFTGSLVGIQVVGDDLTVTKPEARIAKAVEEVKACNCLLLLKVN 366

Query: 343 QIGTLTEAMDAAYMAFRAGYGVV-VSHR-SGETEDATIADLAVALNAGQIKTGAPARSDR 400
           QIG++TE++ A  +A   G+GV+ VSHR SGETED  +ADL V L  GQIKTG   RS+R
Sbjct: 367 QIGSVTESLQACKLAQSNGWGVMPVSHRLSGETEDTFMADLVVGLCTGQIKTGPTCRSER 426

Query: 401 NAKYNQLIRIEE-ELEGVAVYAGKNFR 426
            AKYNQL+RIEE E    A +AG+NFR
Sbjct: 427 LAKYNQLLRIEEAEAGSKARFAGRNFR 453


>gb|AAK41195.1| Enolase [Sulfolobus solfataricus]
           Length = 419
           
 Score =  356 bits (904), Expect = 3e-97
 Identities = 199/428 (46%), Positives = 272/428 (63%), Gaps = 16/428 (3%)

Query: 3   MENPYEIVAVIAREILDSRGNPTVEVDVHTPI---SMGRAAVPSGASTGTHEAVELRDGG 59
           M N + I  V   EI+DSRGNPT+ V + T     S G A  P+GAS GT EAVE+RD  
Sbjct: 1   MINRFSIEKVKGLEIVDSRGNPTIRVFIRTSDGVESFGDA--PAGASKGTREAVEVRDE- 57

Query: 60  KRYHGKGVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSL 119
              +G  V+RAV+ VN II P L G+DVR Q  ID+LL ++D TENKS LG N I+A S+
Sbjct: 58  ---NGLTVKRAVDIVNYIIDPALHGIDVREQGIIDKLLKDIDSTENKSKLGGNTIIATSI 114

Query: 120 AVAKAAANALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFR 179
           A  K A+ AL L +++Y+ G     +P+PL N+INGG+HAGN L  QEF+I+PI  N+F+
Sbjct: 115 AALKTASKALGLEVFKYISGPRLPKIPIPLLNIINGGLHAGNKLKIQEFIIVPIKFNTFK 174

Query: 180 EAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPG 239
           EA+    + Y  LK +I E+YGK    VGDEGGF+PP+++  E LD++  +I  AGY+  
Sbjct: 175 EALFAAIDVYRTLKGLITERYGKIYTAVGDEGGFSPPLEDTREALDLIYTSINNAGYE-- 232

Query: 240 EEIALALDAASSEFY--KDGKYIVSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWE 297
            +I + +DAA S+FY  K  KYI+ G+E    +LLE Y +L   YPIV +EDPF E  ++
Sbjct: 233 GKIYMGMDAAGSDFYDSKKEKYIIDGRELDPNQLLEFYLDLVKQYPIVYLEDPFEENSFD 292

Query: 298 GFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMA 357
            F  +  +L   + I GDDL+ TN K LK GIE  +   +++K NQ+GT++E  +   +A
Sbjct: 293 MFSQLQNKLSSTI-ITGDDLYTTNIKYLKIGIEKRSTKGVIVKPNQVGTISETFEFTNLA 351

Query: 358 FRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGV 417
            R    ++ SHRSGETED  IAD AV + +  IK GAPAR +R +KYN+L+ IE +    
Sbjct: 352 RRNSMKLITSHRSGETEDNFIADFAVGIESDFIKVGAPARGERTSKYNKLLEIENKFG-- 409

Query: 418 AVYAGKNF 425
             Y GK F
Sbjct: 410 LEYEGKYF 417


>gb|AAB88178.1| (AF035286) alpha enolase [Homo sapiens]
           Length = 336
           
 Score =  349 bits (885), Expect = 4e-95
 Identities = 186/335 (55%), Positives = 234/335 (69%), Gaps = 14/335 (4%)

Query: 102 GTENKSNLGANAILAVSLAVAKAAANALELPLYQY---LGGVNAYVLPVPLSNVINGGVH 158
           GTENKS  GANAIL VSLAV KA A    +PLY++   L G +  +LPVP  NVINGG H
Sbjct: 1   GTENKSKFGANAILGVSLAVCKAGAVEKGVPLYRHIADLAGNSEVILPVPAFNVINGGSH 60

Query: 159 AGNDLDFQEFMIMPIGANSFREAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMK 218
           AGN L  QEFMI+P+GA +FREA+R  +E YH LK VI EKYGK+A NVGDEGGFAP + 
Sbjct: 61  AGNKLAMQEFMILPVGAANFREAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNIL 120

Query: 219 EVTEPLDVLIKAIEEAGYKPGEEIALALDAASSEFYKDGKYIVSGKE-------YTREEL 271
           E  E L++L  AI +AGY   +++ + +D A+SEF++ GKY +  K         + ++L
Sbjct: 121 ENKEGLELLKTAIGKAGYT--DKVVIGMDVAASEFFRSGKYDLDFKSPDDPSRYISPDQL 178

Query: 272 LELYKELTSTYPIVSIEDPFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEM 331
            +LYK     YP+VSIEDPF ++DW  +   T   G  +Q+VGDDL VTNPKR+ K +  
Sbjct: 179 ADLYKSFIKDYPVVSIEDPFDQDDWGAWQKFTASAG--IQVVGDDLTVTNPKRIAKAVNE 236

Query: 332 GAANALLLKVNQIGTLTEAMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIK 391
            + N LLLKVNQIG++TE++ A  +A   G+GV+VSHRSGETED  IADL V L  GQIK
Sbjct: 237 KSCNCLLLKVNQIGSVTESLQACKLAQANGWGVMVSHRSGETEDTFIADLVVGLCTGQIK 296

Query: 392 TGAPARSDRNAKYNQLIRIEEELEGVAVYAGKNFR 426
           TGAP RS+R AKYNQL+RIEEEL   A +AG+NFR
Sbjct: 297 TGAPCRSERLAKYNQLLRIEEELGSKAKFAGRNFR 331


>sp|O26149|ENO_METTH ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE
           HYDRO-LYASE) >gi|7436881|pir||A69156 enolase -
           Methanobacterium thermoautotrophicum (strain Delta H)
           >gi|2621078|gb|AAB84550.1| (AE000796) enolase
           [Methanobacterium thermoautotrophicum]
           Length = 416
           
 Score =  329 bits (835), Expect = 3e-89
 Identities = 195/417 (46%), Positives = 262/417 (62%), Gaps = 16/417 (3%)

Query: 3   MENPYEIVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGKRY 62
           ME+  E V V  R+ILDSRGNPTVEVDV T    GRAA PSGASTG+ E      GG   
Sbjct: 1   MESIIEDVRV--RKILDSRGNPTVEVDVITWNGFGRAAAPSGASTGSREVAAFPSGG--- 55

Query: 63  HGKGVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVA 122
               V   +  V  II+ EL+GMD    ++ID +L E+DGTEN S+LG N ++AVS+A A
Sbjct: 56  ----VDEIITEVEDIISSELIGMDAVDLQDIDLVLKEIDGTENLSSLGGNTVVAVSMATA 111

Query: 123 KAAANALELPLYQYLGGVNAYVLPVPLSNVINGGVHAG-NDLDFQEFMIMPIGANSFREA 181
           KAAA++  +PLY++LGG  A  +P PL N+INGG HAG N  D QEF+++P+GA    EA
Sbjct: 112 KAAASSYNMPLYRFLGGNLATSIPYPLGNMINGGAHAGKNAPDIQEFLVVPVGAEDITEA 171

Query: 182 IRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEE 241
           +   +  +  ++++I +K    A   GDEGG+ P +    + L++   A EE   + G E
Sbjct: 172 VFANAAVHKRIRELIQKKDPSFAGGKGDEGGWVPSLSN-GDALEIQATACEEVTDELGVE 230

Query: 242 IALALDAASSEFYKDG--KYIVSGKEYTRE--ELLELYKELTSTYPIVSIEDPFHEEDWE 297
           +  +LD A+SEF+     KY+   +   ++  E +E  KE+  TY +  +EDP HE D E
Sbjct: 231 VRPSLDLAASEFWDPEIEKYVYRQENVQKDTGEQIEFVKEIIETYDMYYVEDPLHEGDLE 290

Query: 298 GFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMA 357
           GF  +T  +G +  I GDD+FVTN + L++GIEMGAANA+++K NQIGTLT+      +A
Sbjct: 291 GFAELTSLVGDRCMICGDDIFVTNREILREGIEMGAANAIIIKPNQIGTLTDTYLTVKLA 350

Query: 358 FRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEEL 414
               Y  VVSHRSGET D TIA LAVA  A  IKTGA    +R AK N+LIRI+EE+
Sbjct: 351 LENRYTPVVSHRSGETTDDTIAHLAVAFGAPLIKTGA-IGGERIAKLNELIRIQEEI 406


>gb|AAC48992.1| (U23472) enolase homolog;  Method: conceptual translation supplied
           by author [Saccharomyces cerevisiae]
           Length = 318
           
 Score =  289 bits (733), Expect = 3e-77
 Identities = 155/316 (49%), Positives = 206/316 (65%), Gaps = 17/316 (5%)

Query: 123 KAAANALELPLYQYLGGV-----NAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANS 177
           +AAA    + LY+Y+  +     + +V+PVP  NV+NGG HAG  L  QEF I P+GA S
Sbjct: 1   RAAAAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQS 60

Query: 178 FREAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYK 237
           F EA+R  SE YH LK +  E+YG +A NVGDEGG AP +    + LD+++KAI   GY+
Sbjct: 61  FAEAMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVKAINICGYE 120

Query: 238 PGEEIALALDAASSEFYKDGKYIVSGKEYTRE--------ELLELYKELTSTYPIVSIED 289
               + + +D+A S FYKDGKY ++ KE   +        +L E Y  L   YPI+S+ED
Sbjct: 121 G--RVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLED 178

Query: 290 PFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTE 349
           P+ E+DW  +    + +   VQI+ DDL  TN  R+ + IE   AN LLLK+NQIGTLTE
Sbjct: 179 PYAEDDWSSWSAFLKTVN--VQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTE 236

Query: 350 AMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIR 409
           +++AA  AF AG+GV++SHRSGETED  IADL V L  GQIK+GA +RS+R AKYN+L+R
Sbjct: 237 SIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLR 296

Query: 410 IEEELEGVAVYAGKNF 425
           IEEEL    +YAG  F
Sbjct: 297 IEEELGDDCIYAGHRF 312


>gb|AAC39935.1| (U88968) alpha enolase like 1 [Homo sapiens]
           Length = 269
           
 Score =  280 bits (710), Expect = 1e-74
 Identities = 146/268 (54%), Positives = 189/268 (70%), Gaps = 11/268 (4%)

Query: 166 QEFMIMPIGANSFREAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLD 225
           QEFMI+P+GA +FREA+R  +E YH LK VI EKYGK+A NVGDEGGFAP + E  E L+
Sbjct: 1   QEFMILPVGAANFREAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEGLE 60

Query: 226 VLIKAIEEAGYKPGEEIALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKEL 278
           +L  AI +AGY   +++ + +D A+SEF++ GKY +  K         + ++L +LYK  
Sbjct: 61  LLKTAIGKAGYT--DKVVIGMDVAASEFFRSGKYDLDFKSPDDPSRYISPDQLADLYKSF 118

Query: 279 TSTYPIVSIEDPFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALL 338
              YP+VSIEDPF ++DW  +   T   G  +Q+VGDDL VTNPKR+ K +   + N LL
Sbjct: 119 IKDYPVVSIEDPFDQDDWGAWQKFTASAG--IQVVGDDLTVTNPKRIAKAVNEKSCNCLL 176

Query: 339 LKVNQIGTLTEAMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARS 398
           LKVNQIG++TE++ A  +A   G+GV+VSHRSGETED  IADL V L  GQIKTGAP RS
Sbjct: 177 LKVNQIGSVTESLQACKLAQANGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRS 236

Query: 399 DRNAKYNQLIRIEEELEGVAVYAGKNFR 426
           +R AKYNQL+RIEEEL   A +AG+NFR
Sbjct: 237 ERLAKYNQLLRIEEELGSKAKFAGRNFR 264


>emb|CAC12011.1| (AL445065) enolase related protein [Thermoplasma acidophilum]
           Length = 401
           
 Score =  272 bits (689), Expect = 4e-72
 Identities = 154/411 (37%), Positives = 245/411 (59%), Gaps = 15/411 (3%)

Query: 3   MENPYEIVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGKRY 62
           ME P E + V  R++LDSRGN TVE DV  P   GR + P+GASTG  E +        +
Sbjct: 1   MELPIEEIKV--RKVLDSRGNFTVEADVTVPNGFGRTSAPAGASTGETEVIA-------F 51

Query: 63  HGKGVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVA 122
              G+  +++     +   L+G +   Q   D+LL ++DG+ N SNLG N   A+S++VA
Sbjct: 52  SKSGIDASIQFFESKVKRSLIGFNALDQSGFDKLLTDIDGSGNFSNLGGNLATALSMSVA 111

Query: 123 KAAANALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182
           KAAA +L +PLY+Y+GG+ +  +P P+ NVI GG HA N    QEF++   G+     A 
Sbjct: 112 KAAAQSLGIPLYRYVGGIRS-TIPRPMGNVIGGGKHARNGTSIQEFLVSAQGSTFLESA- 169

Query: 183 RWVSETYHV-LKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEE 241
            +++   H  +  ++++K+   ++ VGDE  ++  + +  E  ++L +A++E   +   +
Sbjct: 170 -YINVLVHRRIGDMLSDKFKDISIGVGDERTWSVNLSD-EEAFEILNEAVKEISSEKKVK 227

Query: 242 IALALDAASSEFYKDGKYIVSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVM 301
           I   +D A+   Y++GKY+      +R+E ++    ++  + +  IEDP ++ D++GF  
Sbjct: 228 IYTGVDFAADSLYENGKYVYKHTTKSRDEQIDYAISISKDFGVYYIEDPMYDTDFDGFAE 287

Query: 302 ITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAG 361
           IT  +G +  IVGDDL+ TNP R++KG+E  + NA+L+KVNQIGTL+ A +A  +A  AG
Sbjct: 288 ITARIGDRSLIVGDDLYTTNPDRIRKGVEKKSTNAVLIKVNQIGTLSAAREAVAVATFAG 347

Query: 362 YGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEE 412
              +VSHRSGET D  +A L+VA  +  +KTG     +R AK N++ RIEE
Sbjct: 348 MKNIVSHRSGETTDDFLAHLSVAFGSTFVKTGV-IGGERVAKLNEIARIEE 397


>emb|CAB94588.1| (AL359213) ENO3, muscle enolase 3 beta [Homo sapiens]
           Length = 154
           
 Score =  170 bits (426), Expect = 3e-41
 Identities = 87/151 (57%), Positives = 107/151 (70%), Gaps = 2/151 (1%)

Query: 276 KELTSTYPIVSIEDPFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAAN 335
           K     YP+VSIEDPF ++DW  +       G  +QIVGDDL VTNPKR+ + +E  A N
Sbjct: 1   KSFIKNYPVVSIEDPFDQDDWATWTSFLS--GVNIQIVGDDLTVTNPKRIAQAVEKKACN 58

Query: 336 ALLLKVNQIGTLTEAMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAP 395
            LLLKVNQIG++TE++ A  +A   G+GV+VS RSGETED  IADL V L  GQIKTGAP
Sbjct: 59  CLLLKVNQIGSVTESIQACKLAQSNGWGVMVSXRSGETEDTFIADLVVGLCTGQIKTGAP 118

Query: 396 ARSDRNAKYNQLIRIEEELEGVAVYAGKNFR 426
            RS+R AKYNQL+RIEE L   A++AG+ FR
Sbjct: 119 CRSERLAKYNQLMRIEEALGDKAIFAGRKFR 149


>gi|10835228 MYC promoter-binding protein 1 [Homo sapiens]
           >gi|126792|sp|P22712|MBP1_HUMAN C-MYC PROMOTER-BINDING
           PROTEIN >gi|105479|pir||A39579 c-myc promoter-binding
           protein MBP-1 - human >gi|180663|gb|AAA35698.1| (M55914)
           c-myc binding protein [Homo sapiens]
           Length = 335
           
 Score =  155 bits (389), Expect = 6e-37
 Identities = 98/230 (42%), Positives = 131/230 (56%), Gaps = 20/230 (8%)

Query: 208 GDEGGFAPPMKEVTEPLDVLIKAIEEAGY--KPGEEIALALDAASSEFYKDGKYIVSGKE 265
           GD  GFAP + E  E L++L  AI + G   K G      +D A+SEF++ G Y +  K 
Sbjct: 110 GDLRGFAPNILENKEGLELLKTAIGKPGLHCKGGH----GMDVAASEFFRSGNYDLDFKS 165

Query: 266 -------YTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMIT--RELGKKVQIVGDD 316
                   + ++L +LYK     YP+VSIEDPF ++DW    + +  R  G       D 
Sbjct: 166 PDDPSRYISPDQLADLYKSFIKDYPVVSIEDPFDQDDWGASEVHSQCRNPGSGGMTHSDQ 225

Query: 317 LFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYGVVVSHRSGETEDA 376
                PK  ++G+   + N LLLKVNQIG++TE++ A  +A   G+GV+VSHRSGETED 
Sbjct: 226 -----PKEDRQGVNEKSCNCLLLKVNQIGSVTESLQACKLAQANGWGVMVSHRSGETEDT 280

Query: 377 TIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAGKNFR 426
            IADL V L  G  +   P    R AKYNQL+RIEEEL   A +AG+NFR
Sbjct: 281 FIADLVVGLCTGADQDWCPLPITRLAKYNQLLRIEEELGSKAKFAGRNFR 330


>gb|AAA24486.1| (M12843) enolase [Escherichia coli]
           Length = 123
           
 Score =  136 bits (338), Expect = 6e-31
 Identities = 76/121 (62%), Positives = 91/121 (74%), Gaps = 2/121 (1%)

Query: 8   EIVAVIAREILDSRGNPTVEVDVHTPIS-MGRAAVPSGASTGTHEAVELRDGGK-RYHGK 65
           +IV +I REI+DSRGNPTVE +VH     +G AA PSGASTG+ EA+ELRDG K R+ GK
Sbjct: 3   KIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGK 62

Query: 66  GVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125
           GV +AV  VN  IA  L+G D + Q  ID+++I+LDGTE KS  GANAILAVSLA AKAA
Sbjct: 63  GVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTEKKSKFGANAILAVSLANAKAA 122

Query: 126 A 126
           A
Sbjct: 123 A 123


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.316    0.135    0.379 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 157371683
Number of Sequences: 2977
Number of extensions: 6660545
Number of successful extensions: 18966
Number of sequences better than 1.0e-10: 216
Number of HSP's better than  0.0 without gapping: 210
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 17833
Number of HSP's gapped (non-prelim): 221
length of query: 430
length of database: 189,106,746
effective HSP length: 60
effective length of query: 370
effective length of database: 153,197,526
effective search space: 56683084620
effective search space used: 56683084620
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.5 bits)
S2: 166 (69.1 bits)