BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB1126 (eno) DE:enolase (EC 4.2.1.11) (eno) (430 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||H75022 phosphopyruvate hydratase (EC 4.2.1.11) PAB1126 - Py... 853 0.0 sp|O59605|ENO_PYRHO ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 812 0.0 sp|Q60173|ENO_METJA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 597 e-170 dbj|BAB07275.1| (AP001519) enolase (2-phosphoglycerate dehydrata... 520 e-146 pir||A41835 phosphopyruvate hydratase (EC 4.2.1.11) - Bacillus s... 517 e-146 sp|P37869|ENO_BACSU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 517 e-146 emb|CAC09537.1| (AL442120) enolase [Streptomyces coelicolor] 509 e-143 pir||D75251 enolase - Deinococcus radiodurans (strain R1) >gi|64... 506 e-142 sp|O66778|ENO_AQUAE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 503 e-141 sp|P42848|ENO_THEMA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 495 e-139 gb|AAD35958.1|AE001753_14 (AE001753) enolase [Thermotoga maritima] 495 e-139 sp|P96377|ENO_MYCTU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 488 e-137 emb|CAB94910.1| (AJ401152) enolase [Enterococcus faecalis] 487 e-137 dbj|BAB07786.1| (AB046715) enolase [Desulfovibrio vulgaris] 486 e-136 pir||A81841 phosphopyruvate hydratase (EC 4.2.1.11) NMA1495 [imp... 481 e-135 pir||D81100 enolase NMB1285 [imported] - Neisseria meningitidis ... 480 e-134 sp|O51312|ENO_BORBU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 474 e-133 sp|P42894|ENO_NEOFR ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 474 e-132 pir||T12341 phosphopyruvate hydratase (EC 4.2.1.11) - common ice... 473 e-132 sp|Q43130|ENO_MESCR ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 473 e-132 gb|AAC46289.1| (AF000366) enolase homolog [Borrelia burgdorferi] 473 e-132 emb|CAB75428.1| (AJ271785) enolase [Lupinus luteus] 473 e-132 emb|CAB96173.1| (AJ271719) enolase [Spinacia oleracea] 469 e-131 sp|P77972|ENO_SYNY3 ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 468 e-131 sp|P74934|ENO_TREPA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 467 e-131 sp|O69174|ENO_STAAU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 466 e-130 sp|P07323|ENOG_RAT GAMMA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-LY... 466 e-130 gi|5803011 enolase 2, (gamma, neuronal); Enolase-2, gamma, neuro... 466 e-130 sp|P30575|ENO1_CANAL ENOLASE 1 (2-PHOSPHOGLYCERATE DEHYDRATASE) ... 466 e-130 sp|Q27727|ENO_PLAFA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 465 e-130 emb|CAA31512.1| (X13120) neurone-specific enolase [Homo sapiens]... 465 e-130 sp|P26300|ENO_LYCES ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 465 e-130 sp|P09104|ENOG_HUMAN GAMMA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-... 465 e-130 dbj|BAA76924.1| (AB026051) enolase [Plasmodium falciparum] 464 e-130 pir||JC1039 phosphopyruvate hydratase (EC 4.2.1.11) - rat 464 e-130 pir||A53665 phosphopyruvate hydratase (EC 4.2.1.11) - liver fluke 464 e-129 gi|7305027 enolase 2, gamma neuronal [Mus musculus] >gi|119348|s... 463 e-129 emb|CAC00532.1| (AJ132580) enolase, isoform 1 [Hevea brasiliensis] 463 e-129 sp|P42896|ENO_RICCO ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 462 e-129 sp|O57391|ENOG_CHICK GAMMA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-... 462 e-129 sp|O85348|ENO_NITEU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 462 e-129 sp|Q27655|ENO_FASHE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 462 e-129 pir||A72477 probable enolase APE2458 - Aeropyrum pernix (strain ... 462 e-129 sp|P25696|ENO_ARATH ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 461 e-129 sp|Q42971|ENO_ORYSA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 460 e-128 gb|AAD41646.1|AF072589_1 (AF072589) alpha enolase [Python regius] 460 e-128 sp|P42895|ENO2_MAIZE ENOLASE 2 (2-PHOSPHOGLYCERATE DEHYDRATASE 2... 460 e-128 sp|P08324|ENO_ECOLI ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 460 e-128 sp|P33675|ENO_ZYMMO ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 459 e-128 dbj|BAA81815.1| (AB029313) enolase [Streptococcus intermedius] 459 e-128 sp|Q43321|ENO_ALNGL ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 458 e-128 emb|CAC00533.1| (AJ132581) enolase, isoform 2 [Hevea brasiliensis] 458 e-128 gb|AAD41643.1|AF072586_1 (AF072586) alpha enolase [Alligator mis... 458 e-128 sp|P08734|ENO_XENLA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 457 e-128 sp|P51913|ENOA_CHICK ALPHA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-... 456 e-127 gb|AAD41645.1|AF072588_1 (AF072588) alpha enolase [Trachemys scr... 455 e-127 sp|O02654|ENO_LOLPE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 454 e-127 sp|P26301|ENO1_MAIZE ENOLASE 1 (2-PHOSPHOGLYCERATE DEHYDRATASE 1... 453 e-126 sp|P19140|ENOA_ANAPL ALPHA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-... 453 e-126 emb|CAA76735.1| (Y17298) enolase [Cunninghamella elegans] 453 e-126 sp|P42040|ENO_CLAHE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 453 e-126 gi|4503571 enolase 1, (alpha); Enolase-1, alpha; phosphopyruvate... 453 e-126 gb|AAF13454.1|AF205070_1 (AF205070) enolase [Mastigamoeba balamu... 453 e-126 emb|CAA57795.1| (X82400) enolase [Escherichia coli] 453 e-126 sp|P17182|ENOA_MOUSE ALPHA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-... 451 e-126 pir||S06756 phosphopyruvate hydratase (EC 4.2.1.11) beta - human... 451 e-126 gi|4503573 enolase 3, (beta, muscle); Enolase-3, beta, muscle [H... 451 e-126 sp|P33676|ENO_SCHJA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 451 e-126 emb|CAA59331.1| (X84907) carbonate dehydratase [Homo sapiens] 451 e-126 gi|11426964 enolase 3, (beta, muscle) [Homo sapiens] >gi|416950|... 450 e-125 sp|Q27527|ENO_CAEEL ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 450 e-125 gb|AAD41644.1|AF072587_1 (AF072587) alpha enolase [Sceloporus un... 450 e-125 pir||A37210 phosphopyruvate hydratase (EC 4.2.1.11) beta - rabbit 450 e-125 sp|P25704|ENOB_RABIT BETA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-L... 450 e-125 gi|6679651 enolase 3, beta muscle [Mus musculus] >gi|119344|sp|P... 449 e-125 emb|CAB96125.1| (AJ272111) enolase [Euglena gracilis] 449 e-125 gi|6978809 enolase 1, alpha [Rattus norvegicus] >gi|119341|sp|P0... 449 e-125 gb|AAF71925.1|AF260259_1 (AF260259) beta beta enolase [Oryctolag... 448 e-125 pir||S43113 phosphopyruvate hydratase (EC 4.2.1.11) - fungus (C... 446 e-124 gb|AAF36733.1| (AC016662) putative enolase; 31277-33713 [Arabido... 446 e-124 sp|Q12560|ENO_ASPOR ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 445 e-124 pir||T39737 enolase - fission yeast (Schizosaccharomyces pombe) ... 444 e-124 sp|Q27877|ENO_SCHMA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 443 e-123 gb|AAC78141.1| (AF100985) phosphopyruvate hydratase [Penaeus mon... 442 e-123 sp|Q9ZMS6|ENO_HELPJ ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 441 e-123 gb|AAD33073.1|AF149256_1 (AF149256) alpha enolase [Bos taurus] 441 e-123 gb|AAF73201.1|AF152348_1 (AF152348) enolase [Trypanosoma brucei ... 441 e-123 pir||E82076 enolase VC2447 [imported] - Vibrio cholerae (group O... 441 e-123 sp|P43806|ENO_HAEIN ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 441 e-123 sp|P42448|ENO_CAMJE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 441 e-123 pir||F82700 enolase XF1291 [imported] - Xylella fastidiosa (stra... 439 e-122 pdb|1PDZ| Mol_id: 1; Molecule: Enolase; Chain: Null; Synonym: ... 439 e-122 sp|P56252|ENO_HOMGA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 439 e-122 sp|P48285|ENO_HELPY ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 439 e-122 emb|CAB94039.1| (AL358652) enolase [Leishmania major] 437 e-121 emb|CAB96126.1| (AJ272112) chloroplast enolase [Euglena gracilis] 436 e-121 pir||H83191 enolase PA3635 [imported] - Pseudomonas aeruginosa (... 436 e-121 gi|6978811 muscle specific enolase (beta beta enolose) (two spli... 436 e-121 gi|6321693 enolase I; Eno1p [Saccharomyces cerevisiae] >gi|21445... 436 e-121 sp|P00924|ENO1_YEAST ENOLASE 1 (2-PHOSPHOGLYCERATE DEHYDRATASE) ... 436 e-121 pdb|1ONE|A Chain A, Yeast Enolase Complexed With An Equilibrium ... 436 e-121 pdb|4ENL| Enolase (E.C.4.2.1.11) (2-Phospho-D-Glycerate Hydrol... 434 e-121 gb|AAD02812.1| (AF063247) enolase [Pneumocystis carinii f. sp. r... 433 e-120 sp|P07322|ENOB_CHICK BETA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-L... 433 e-120 sp|O52191|ENO_STRTR ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 432 e-120 gb|AAF51344.1| (AE003585) Eno gene product [Drosophila melanogas... 432 e-120 pir||I56569 gamma enolase - human (fragment) >gi|182118|gb|AAA52... 431 e-120 sp|P15007|ENO_DROME ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 431 e-120 sp|P51555|ENO1_ENTHI ENOLASE 1 (2-PHOSPHOGLYCERATE DEHYDRATASE) ... 430 e-119 gb|AAD51128.1|AF051910_1 (AF051910) enolase [Toxoplasma gondii] 430 e-119 gi|6321968 enolase; Eno2p [Saccharomyces cerevisiae] >gi|119337|... 428 e-119 emb|CAC16971.1| (AL450350) enolase [Streptomyces coelicolor] 428 e-119 sp|P40370|ENO1_SCHPO ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2... 427 e-118 pir||A23850 phosphopyruvate hydratase (EC 4.2.1.11), skeletal mu... 426 e-118 sp|P75189|ENO_MYCPN ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 421 e-117 pir||E81654 enolase TC0876 [imported] - Chlamydia muridarum (str... 419 e-116 sp|Q9Z7A6|ENO_CHLPN ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 417 e-115 gi|6323985 Ymr323wp [Saccharomyces cerevisiae] >gi|1706698|sp|P4... 416 e-115 pir||G81504 enolase CP1071 [imported] - Chlamydophila pneumoniae... 416 e-115 sp|O84591|ENO_CHLTR ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 414 e-114 gi|6324969 enolase homolog; Err1p [Saccharomyces cerevisiae] >gi... 413 e-114 sp|P57492|ENO_BUCAI ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 411 e-114 dbj|BAA88483.1| (AB025330) enolase-2 [Lampetra reissneri] 408 e-113 gb|AAB87891.1| (AF025806) enolase [Drosophila subobscura] 406 e-112 sp|P47647|ENO_MYCGE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 403 e-111 gb|AAB87890.1| (AF025805) enolase [Drosophila pseudoobscura] 403 e-111 dbj|BAA88479.1| (AB025326) enolase [Eptatretus burgeri] 403 e-111 gb|AAC95183.1| (AC004561) putative enolase (2-phospho-D-glycerat... 400 e-110 dbj|BAA88482.1| (AB025329) enolase-1 [Lampetra reissneri] 400 e-110 sp|P31683|ENO_CHLRE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 393 e-108 gb|AAA49217.1| (M55143) alpha-enolase/tau-crystallin [Anas platy... 388 e-107 gb|AAA37554.1| (M20745) muscle-specific enolase beta subunit (EC... 374 e-103 pir||H82922 enolase UU184 [imported] - Ureaplasma urealyticum >g... 369 e-101 gi|7657062 enolase alpha, lung-specific [Homo sapiens] >gi|72942... 363 2e-99 gb|AAK41195.1| Enolase [Sulfolobus solfataricus] 356 3e-97 gb|AAB88178.1| (AF035286) alpha enolase [Homo sapiens] 349 4e-95 sp|O26149|ENO_METTH ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-... 329 3e-89 gb|AAC48992.1| (U23472) enolase homolog; Method: conceptual tra... 289 3e-77 gb|AAC39935.1| (U88968) alpha enolase like 1 [Homo sapiens] 280 1e-74 emb|CAC12011.1| (AL445065) enolase related protein [Thermoplasma... 272 4e-72 emb|CAB94588.1| (AL359213) ENO3, muscle enolase 3 beta [Homo sap... 170 3e-41 gi|10835228 MYC promoter-binding protein 1 [Homo sapiens] >gi|12... 155 6e-37 gb|AAA24486.1| (M12843) enolase [Escherichia coli] 136 6e-31 >pir||H75022 phosphopyruvate hydratase (EC 4.2.1.11) PAB1126 - Pyrococcus abyssi (strain Orsay) >gi|5459136|emb|CAB50622.1| (AJ248288) enolase (EC 4.2.1.11) (eno) [Pyrococcus abyssi] Length = 430 Score = 853 bits (2180), Expect = 0.0 Identities = 430/430 (100%), Positives = 430/430 (100%) Query: 1 MTMENPYEIVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK 60 MTMENPYEIVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK Sbjct: 1 MTMENPYEIVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK 60 Query: 61 RYHGKGVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLA 120 RYHGKGVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLA Sbjct: 61 RYHGKGVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLA 120 Query: 121 VAKAAANALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFRE 180 VAKAAANALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFRE Sbjct: 121 VAKAAANALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFRE 180 Query: 181 AIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGE 240 AIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGE Sbjct: 181 AIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGE 240 Query: 241 EIALALDAASSEFYKDGKYIVSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFV 300 EIALALDAASSEFYKDGKYIVSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFV Sbjct: 241 EIALALDAASSEFYKDGKYIVSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFV 300 Query: 301 MITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRA 360 MITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRA Sbjct: 301 MITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRA 360 Query: 361 GYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVY 420 GYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVY Sbjct: 361 GYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVY 420 Query: 421 AGKNFRKVFF 430 AGKNFRKVFF Sbjct: 421 AGKNFRKVFF 430 >sp|O59605|ENO_PYRHO ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|7436873|pir||F71209 probable phosphoglycerate dehydratase - Pyrococcus horikoshii >gi|3258386|dbj|BAA31069.1| (AP000007) 428aa long hypothetical phosphoglycerate dehydratase [Pyrococcus horikoshii] Length = 428 Score = 812 bits (2075), Expect = 0.0 Identities = 400/428 (93%), Positives = 418/428 (97%) Query: 3 MENPYEIVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGKRY 62 MENPYEI A++AREILDSRGNPTVEVDVHTPI+MGRAAVPSGASTGTHEAVELRDGGKRY Sbjct: 1 MENPYEITAIVAREILDSRGNPTVEVDVHTPIAMGRAAVPSGASTGTHEAVELRDGGKRY 60 Query: 63 HGKGVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVA 122 HGKGVRRAVENVNKIIAPEL+GMDVRWQREID+LLIELDGTENKSNLGANAILAVSLAVA Sbjct: 61 HGKGVRRAVENVNKIIAPELIGMDVRWQREIDKLLIELDGTENKSNLGANAILAVSLAVA 120 Query: 123 KAAANALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182 KAAAN+LELPLYQYLGGVNAYVLPVPLSNVINGGVHAGN+LDFQEFMIMPIGA+SFREAI Sbjct: 121 KAAANSLELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNELDFQEFMIMPIGASSFREAI 180 Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242 RWVSETYHVLK+VI KYGKNAVNVGDEGGFAPPMKEVTEPLD LIKAIEEAGYKPG+EI Sbjct: 181 RWVSETYHVLKRVIMGKYGKNAVNVGDEGGFAPPMKEVTEPLDALIKAIEEAGYKPGDEI 240 Query: 243 ALALDAASSEFYKDGKYIVSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMI 302 ALA+DAASSEF+KDGKYIV GKEYTREELL+LYKEL STYPIVSIEDPFHEEDWEGFVMI Sbjct: 241 ALAIDAASSEFFKDGKYIVGGKEYTREELLDLYKELVSTYPIVSIEDPFHEEDWEGFVMI 300 Query: 303 TRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGY 362 T ELGKK+QIVGDDLFVTNP+RLKKGIE+GAANALLLKVNQIGTLTEAMDAAY AFRAGY Sbjct: 301 TNELGKKIQIVGDDLFVTNPRRLKKGIELGAANALLLKVNQIGTLTEAMDAAYTAFRAGY 360 Query: 363 GVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAG 422 V+VSHRSGETED TIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEG+AVYAG Sbjct: 361 SVIVSHRSGETEDTTIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGIAVYAG 420 Query: 423 KNFRKVFF 430 KNFRKVFF Sbjct: 421 KNFRKVFF 428 >sp|Q60173|ENO_METJA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|2118303|pir||A64329 phosphopyruvate hydratase (EC 4.2.1.11) - Methanococcus jannaschii >gi|1590967|gb|AAB98220.1| (U67479) enolase (eno) [Methanococcus jannaschii] Length = 427 Score = 597 bits (1522), Expect = e-170 Identities = 306/428 (71%), Positives = 356/428 (82%), Gaps = 6/428 (1%) Query: 3 MENPYEIVAVIAREILDSRGNPTVEVDVHTPIS-MGRAAVPSGASTGTHEAVELRDGGKR 61 M+ +EI ++ARE++DSRGNPTVEV+V T + G A VPSGASTGTHEA+ELRD KR Sbjct: 5 MDERFEIKDIVAREVIDSRGNPTVEVEVITKGNGYGSAIVPSGASTGTHEALELRDKEKR 64 Query: 62 YHGKGVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAV 121 + GKGV AVENVN II PE++G D R QREID ++IELDGT NKS LGANAILAVSLAV Sbjct: 65 FGGKGVLMAVENVNSIIRPEILGYDARMQREIDTIMIELDGTPNKSRLGANAILAVSLAV 124 Query: 122 AKAAANALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREA 181 AKAAA ++PLY+YLGG N+YV+PVP+ NVINGG HAGNDLD QEFMIMP+GA S EA Sbjct: 125 AKAAAATAKIPLYKYLGGFNSYVMPVPMMNVINGGKHAGNDLDLQEFMIMPVGATSISEA 184 Query: 182 IRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEE 241 +R SE YHVLK VI EKYGKNAVNVGDEGGFAPP+K E LD+L +++++AGY+ +E Sbjct: 185 VRMGSEVYHVLKNVILEKYGKNAVNVGDEGGFAPPLKTSREALDLLTESVKKAGYE--DE 242 Query: 242 IALALDAASSEFYKDGKYIVSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVM 301 + ALDAA+SEFYKDG Y V GK+ TREELL+ YK L YPIVSIEDPFHEED+EGF M Sbjct: 243 VVFALDAAASEFYKDGYYYVEGKKLTREELLDYYKALVDEYPIVSIEDPFHEEDFEGFAM 302 Query: 302 ITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAG 361 IT+EL +QIVGDDLFVTN +RL+KGIEM AANALLLKVNQIGTL+EA+DAA +AFR G Sbjct: 303 ITKEL--DIQIVGDDLFVTNVERLRKGIEMKAANALLLKVNQIGTLSEAVDAAQLAFRNG 360 Query: 362 YGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYA 421 YGVVVSHRSGETED TIADL+VALN+GQIKTGAPAR +R AKYNQLIRIE+EL G++ YA Sbjct: 361 YGVVVSHRSGETEDTTIADLSVALNSGQIKTGAPARGERTAKYNQLIRIEQEL-GLSKYA 419 Query: 422 GKNFRKVF 429 G+NFR F Sbjct: 420 GRNFRCPF 427 >dbj|BAB07275.1| (AP001519) enolase (2-phosphoglycerate dehydratase) [Bacillus halodurans] Length = 429 Score = 520 bits (1325), Expect = e-146 Identities = 271/419 (64%), Positives = 327/419 (77%), Gaps = 7/419 (1%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRDGGKRYHGKGV 67 I V ARE+LDSRGNPTVEV+V+ +MGRA VPSGASTG +EAVELRDGG+R+ GKGV Sbjct: 4 ITDVYAREVLDSRGNPTVEVEVYLESGAMGRALVPSGASTGEYEAVELRDGGERFLGKGV 63 Query: 68 RRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAAN 127 +AVENVN++IAPEL+G D Q ID+ +IELDGTENK LGANAIL VS+AVA+AAAN Sbjct: 64 LKAVENVNEVIAPELIGFDALDQIGIDQHMIELDGTENKGKLGANAILGVSMAVARAAAN 123 Query: 128 ALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVSE 187 AL+LPLY YLGG NA LPVP+ N+INGG HA N++D QEFMIMP+GA SF+EA+R +E Sbjct: 124 ALDLPLYVYLGGFNAKQLPVPMMNIINGGEHADNNVDIQEFMIMPVGAESFKEALRTGTE 183 Query: 188 TYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALALD 247 +H LKKV+ K G N VGDEGGFAP + E L +I+AIE+AGY PGE++ LA+D Sbjct: 184 IFHSLKKVLKSK-GYNTA-VGDEGGFAPNLSSNEEALQTIIEAIEQAGYTPGEQVKLAMD 241 Query: 248 AASSEFY--KDGKYIVS--GKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMIT 303 ASSE Y +DGKY +S GK + EE++ Y+EL + YPI+SIED E DWEG M+T Sbjct: 242 VASSELYNKEDGKYHLSGEGKVLSSEEMVAFYEELVAKYPIISIEDGLDENDWEGHKMLT 301 Query: 304 RELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYG 363 LG KVQ+VGDDLFVTN K+L +GIE G N++L+KVNQIGTLTE DA MA RAGY Sbjct: 302 DRLGDKVQLVGDDLFVTNTKKLAQGIEQGVGNSILIKVNQIGTLTETFDAIEMAKRAGYT 361 Query: 364 VVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAG 422 V+SHRSGETED+TIAD+AVA NAGQIKTGAP+R+DR AKYNQL+RIE+EL +A Y G Sbjct: 362 AVISHRSGETEDSTIADIAVATNAGQIKTGAPSRTDRVAKYNQLLRIEDELGNLAQYNG 420 >pir||A41835 phosphopyruvate hydratase (EC 4.2.1.11) - Bacillus subtilis >gi|460259|gb|AAA21681.1| (L29475) enolase [Bacillus subtilis] Length = 430 Score = 517 bits (1318), Expect = e-146 Identities = 272/425 (64%), Positives = 332/425 (78%), Gaps = 9/425 (2%) Query: 6 PYEIVAVIAREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRDGGK-RYH 63 PY IV V ARE+LDSRGNPTVEV+V+T + GRA VPSGASTG +EAVELRDG K RY Sbjct: 2 PY-IVDVYAREVLDSRGNPTVEVEVYTETGAFGRALVPSGASTGQYEAVELRDGDKDRYL 60 Query: 64 GKGVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAK 123 GKGV AV NVN+IIAPEL+G DV Q ID+LLIELDGTENK LGANAIL VS+A A+ Sbjct: 61 GKGVLTAVNNVNEIIAPELLGFDVTEQNAIDQLLIELDGTENKGKLGANAILGVSMACAR 120 Query: 124 AAANALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIR 183 AAA+ L++PLYQYLGG N+ LPVP+ N++NGG HA N++D QEFMIMP+GA +FREA+R Sbjct: 121 AAADFLQIPLYQYLGGFNSKTLPVPMMNIVNGGEHADNNVDIQEFMIMPVGAPNFREALR 180 Query: 184 WVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIA 243 ++ +H LK V++ K G N VGDEGGFAP + E L +++AIE+AG+KPGEE+ Sbjct: 181 MGAQIFHSLKSVLSAK-GLNTA-VGDEGGFAPNLGSNEEALQTIVEAIEKAGFKPGEEVK 238 Query: 244 LALDAASSEFY--KDGKYIVSGKEY--TREELLELYKELTSTYPIVSIEDPFHEEDWEGF 299 LA+DAASSEFY +DGKY +SG+ T E+++ Y+EL S YPI+SIED E DWEG Sbjct: 239 LAMDAASSEFYNKEDGKYHLSGEGVVKTSAEMVDWYEELVSKYPIISIEDGLDENDWEGH 298 Query: 300 VMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFR 359 ++T LGKKVQ+VGDDLFVTN K+L +GI+ G N++L+KVNQIGTLTE DA MA R Sbjct: 299 KLLTERLGKKVQLVGDDLFVTNTKKLSEGIKNGVGNSILIKVNQIGTLTETFDAIEMAKR 358 Query: 360 AGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAV 419 AGY V+SHRSGETED+TIAD+AVA NAGQIKTGAP+R+DR AKYNQL+RIE++L A Sbjct: 359 AGYTAVISHRSGETEDSTIADIAVATNAGQIKTGAPSRTDRVAKYNQLLRIEDQLAETAQ 418 Query: 420 YAGKN 424 Y G N Sbjct: 419 YHGIN 423 >sp|P37869|ENO_BACSU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|7436878|pir||B69620 phosphopyruvate hydratase (EC 4.2.1.11) [validated] - Bacillus subtilis >gi|2635903|emb|CAB15395.1| (Z99121) enolase [Bacillus subtilis] Length = 430 Score = 517 bits (1318), Expect = e-146 Identities = 272/425 (64%), Positives = 332/425 (78%), Gaps = 9/425 (2%) Query: 6 PYEIVAVIAREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRDGGK-RYH 63 PY IV V ARE+LDSRGNPTVEV+V+T + GRA VPSGASTG +EAVELRDG K RY Sbjct: 2 PY-IVDVYAREVLDSRGNPTVEVEVYTETGAFGRALVPSGASTGEYEAVELRDGDKDRYL 60 Query: 64 GKGVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAK 123 GKGV AV NVN+IIAPEL+G DV Q ID+LLIELDGTENK LGANAIL VS+A A+ Sbjct: 61 GKGVLTAVNNVNEIIAPELLGFDVTEQNAIDQLLIELDGTENKGKLGANAILGVSMACAR 120 Query: 124 AAANALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIR 183 AAA+ L++PLYQYLGG N+ LPVP+ N++NGG HA N++D QEFMIMP+GA +FREA+R Sbjct: 121 AAADFLQIPLYQYLGGFNSKTLPVPMMNIVNGGEHADNNVDIQEFMIMPVGAPNFREALR 180 Query: 184 WVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIA 243 ++ +H LK V++ K G N VGDEGGFAP + E L +++AIE+AG+KPGEE+ Sbjct: 181 MGAQIFHSLKSVLSAK-GLNTA-VGDEGGFAPNLGSNEEALQTIVEAIEKAGFKPGEEVK 238 Query: 244 LALDAASSEFY--KDGKYIVSGKEY--TREELLELYKELTSTYPIVSIEDPFHEEDWEGF 299 LA+DAASSEFY +DGKY +SG+ T E+++ Y+EL S YPI+SIED E DWEG Sbjct: 239 LAMDAASSEFYNKEDGKYHLSGEGVVKTSAEMVDWYEELVSKYPIISIEDGLDENDWEGH 298 Query: 300 VMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFR 359 ++T LGKKVQ+VGDDLFVTN K+L +GI+ G N++L+KVNQIGTLTE DA MA R Sbjct: 299 KLLTERLGKKVQLVGDDLFVTNTKKLSEGIKNGVGNSILIKVNQIGTLTETFDAIEMAKR 358 Query: 360 AGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAV 419 AGY V+SHRSGETED+TIAD+AVA NAGQIKTGAP+R+DR AKYNQL+RIE++L A Sbjct: 359 AGYTAVISHRSGETEDSTIADIAVATNAGQIKTGAPSRTDRVAKYNQLLRIEDQLAETAQ 418 Query: 420 YAGKN 424 Y G N Sbjct: 419 YHGIN 423 >emb|CAC09537.1| (AL442120) enolase [Streptomyces coelicolor] Length = 426 Score = 509 bits (1297), Expect = e-143 Identities = 264/418 (63%), Positives = 321/418 (76%), Gaps = 4/418 (0%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRDGG-KRYHGKG 66 I V+AREILDSRGNPTVEV+V S GRAAVPSGASTG EA+ELRDG RY GKG Sbjct: 4 IDVVVAREILDSRGNPTVEVEVGLDDGSTGRAAVPSGASTGAFEAIELRDGDPSRYLGKG 63 Query: 67 VRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAA 126 V +AV V + I PELVG D QR ID+ + +LD T+NK +LGANAIL VSLAVA AA+ Sbjct: 64 VEKAVLAVIEQIGPELVGYDATEQRLIDQAMFDLDATDNKGSLGANAILGVSLAVAHAAS 123 Query: 127 NALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVS 186 A +LPL++YLGG NA++LPVP+ N++NGG HA +++D QEFMI PIGA SF EA+RW + Sbjct: 124 EASDLPLFRYLGGPNAHLLPVPMMNILNGGSHADSNVDIQEFMIAPIGAESFSEALRWGA 183 Query: 187 ETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALAL 246 E YH LKKV+ K A +GDEGGFAP + E LD++++AI+EAGY PGE+IALAL Sbjct: 184 EVYHTLKKVLKNK--GLATGLGDEGGFAPNLGSNREALDLILEAIKEAGYTPGEQIALAL 241 Query: 247 DAASSEFYKDGKYIVSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMITREL 306 D A+SEFYKDG Y GK + E+ E Y EL YP+VSIEDP E+DW+G+ IT +L Sbjct: 242 DVAASEFYKDGSYAFEGKNRSAAEMTEYYAELVEAYPLVSIEDPLFEDDWDGWNTITAKL 301 Query: 307 GKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYGVVV 366 G KVQ+VGDDLFVTNP+RL +GIE +ANALL+KVNQIG+LTE +DA +A R G+ ++ Sbjct: 302 GDKVQLVGDDLFVTNPERLARGIEENSANALLVKVNQIGSLTETLDAVELAQRNGFKCMM 361 Query: 367 SHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAGKN 424 SHRSGETED TIADLAVA N GQIKTGAPARS+R AKYNQL+RIEE L+ AVYAG++ Sbjct: 362 SHRSGETEDVTIADLAVATNCGQIKTGAPARSERVAKYNQLLRIEEILDDAAVYAGRS 419 >pir||D75251 enolase - Deinococcus radiodurans (strain R1) >gi|6460466|gb|AAF12173.1|AE002092_11 (AE002092) enolase [Deinococcus radiodurans] Length = 422 Score = 506 bits (1289), Expect = e-142 Identities = 253/418 (60%), Positives = 329/418 (78%), Gaps = 5/418 (1%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISM-GRAAVPSGASTGTHEAVELRDGGKRYHGKGV 67 I VIARE+LDSRGNPTVE +VH GRA VPSGASTG+HEA+ELRDGG+RY GKGV Sbjct: 3 IEKVIAREVLDSRGNPTVEAEVHLDSGFSGRAIVPSGASTGSHEALELRDGGERYMGKGV 62 Query: 68 RRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAAN 127 RAV+NV + + P L+GMD Q ID+ L+++DGT NK N+G NAILAVSLA A+AAA Sbjct: 63 ERAVQNVREALGPALIGMDASEQAAIDKALMDVDGTSNKGNMGGNAILAVSLATARAAAA 122 Query: 128 ALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVSE 187 L++PLY+YLGG NA LPVP+ NVINGG HA N +DFQEFM+MP+GA SFREA+R+ +E Sbjct: 123 ELDIPLYRYLGGSNAKTLPVPMMNVINGGAHADNSVDFQEFMVMPVGAPSFREALRYGAE 182 Query: 188 TYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALALD 247 T+H LKKV++ + G N NVGDEGGFAP +K E L+VL++AI++AGY+PG++I +ALD Sbjct: 183 TFHHLKKVLSGR-GYN-TNVGDEGGFAPDLKSNEEALEVLLEAIQQAGYEPGKDICIALD 240 Query: 248 AASSEFYKDGKYIV--SGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMITRE 305 A +E YKDG+Y + G+ + +E+++ + + TS YPIVSIED E+DW+G+ +T + Sbjct: 241 PAVTELYKDGQYHLESEGRVLSSDEMIDFWADWTSRYPIVSIEDGLAEDDWDGWERLTAK 300 Query: 306 LGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYGVV 365 +G K Q+VGDDLFVTNP+RL++GI+ NA+L+KVNQIG+LTE+MDA +A R YG + Sbjct: 301 VGAKTQLVGDDLFVTNPERLQQGIDRKVGNAILVKVNQIGSLTESMDAIELAKRHHYGTI 360 Query: 366 VSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAGK 423 +SHRSGE+EDA IADLAVA NAGQIKTG+ +RSDR AKYNQL+RIE++L AV+ G+ Sbjct: 361 ISHRSGESEDAFIADLAVATNAGQIKTGSASRSDRIAKYNQLLRIEDQLGDRAVFPGR 418 >sp|O66778|ENO_AQUAE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|7436875|pir||F70343 enolase - Aquifex aeolicus >gi|2983135|gb|AAC06738.1| (AE000692) enolase [Aquifex aeolicus] Length = 426 Score = 503 bits (1280), Expect = e-141 Identities = 259/417 (62%), Positives = 319/417 (76%), Gaps = 4/417 (0%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRDGG-KRYHGKG 66 I V RE+LDSRGNPTVEV+V ++GRA VPSGASTG EA+ELRDG KRY GKG Sbjct: 4 IKRVHGREVLDSRGNPTVEVEVELESGALGRAIVPSGASTGEREALELRDGDPKRYLGKG 63 Query: 67 VRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAA 126 V +AV+NVN +IA LVG++ QREID++LIELDGTENKS LGANAIL S+AVA+AAA Sbjct: 64 VLKAVDNVNGVIAKALVGLEPYNQREIDQILIELDGTENKSKLGANAILGTSMAVARAAA 123 Query: 127 NALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVS 186 N L +PLY+YLGG Y LPVPL NVINGG HA N+LD QEFMI+P+ +FREA+R Sbjct: 124 NELGIPLYEYLGGKFGYRLPVPLMNVINGGAHADNNLDIQEFMIVPVCGGAFREALRAGV 183 Query: 187 ETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALAL 246 ET+H LKK++ EK + NVGDEGGFAP + E LD+L++AIE+AGYKPGE+I LAL Sbjct: 184 ETFHHLKKILKEK--GYSTNVGDEGGFAPNLNSSEEALDILMQAIEKAGYKPGEDILLAL 241 Query: 247 DAASSEFYKDGKYIVSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMITREL 306 D ASSEFY++G Y GKE + EE++E Y++L YPI+SIEDP E DWEG+ IT+ L Sbjct: 242 DVASSEFYENGVYKFEGKERSAEEMIEFYEKLIQKYPIISIEDPMSENDWEGWKEITKRL 301 Query: 307 GKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYGVVV 366 G KVQ+VGDDLF TNPK L+KGIE G ANA+L+K+NQIGT++E +D +A Y ++ Sbjct: 302 GDKVQLVGDDLFTTNPKILRKGIEEGVANAILVKLNQIGTVSETLDTVMLAKERNYSAII 361 Query: 367 SHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAGK 423 SHRSGETED I+ LAVA NAGQIKTG+ +R+DR AKYN+L+RIEE L AV+ G+ Sbjct: 362 SHRSGETEDTFISHLAVATNAGQIKTGSASRTDRIAKYNELLRIEERLGNGAVFWGR 418 >sp|P42848|ENO_THEMA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|7436890|pir||G72323 phosphopyruvate hydratase (EC 4.2.1.11) - Thermotoga maritima (strain MSB8) Length = 429 Score = 495 bits (1261), Expect = e-139 Identities = 266/426 (62%), Positives = 325/426 (75%), Gaps = 7/426 (1%) Query: 8 EIVAVIAREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRDGGK-RYHGK 65 EIV V ARE+LDSRGNPTVE +V +MGRA VPSGASTG EA+E+RD K RY GK Sbjct: 4 EIVDVRAREVLDSRGNPTVEAEVVLEDGTMGRAIVPSGASTGKFEALEIRDKDKKRYLGK 63 Query: 66 GVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 GV +AVENVN+ IAP L+GM+ Q +D+ LIELDGTENKS LGANAILAVS+AVA+AA Sbjct: 64 GVLKAVENVNETIAPALIGMNAFDQPLVDKTLIELDGTENKSKLGANAILAVSMAVARAA 123 Query: 126 ANALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWV 185 AN L LPLY+YLGGVNA VLPVPL NVINGG HA N+LD QEFMI+P G +SFREA+R Sbjct: 124 ANYLGLPLYKYLGGVNAKVLPVPLMNVINGGQHADNNLDLQEFMIVPAGFDSFREALRAG 183 Query: 186 SETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALA 245 +E +H LKK++ E + VGDEGGFAP + E + VLI+AIE+AGYKPGEE+ +A Sbjct: 184 AEIFHTLKKILHE--AGHVTAVGDEGGFAPNLSSNEEAIKVLIEAIEKAGYKPGEEVFIA 241 Query: 246 LDAASSEFYKD--GKYIVSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMIT 303 LD A+S FY + G Y V G+E + E L+ Y+EL + YPI+SIEDPF EEDW+ FV T Sbjct: 242 LDCAASSFYDEEKGVYYVDGEEKSSEVLMGYYEELVAKYPIISIEDPFAEEDWDAFVEFT 301 Query: 304 RELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYG 363 + +G KVQIVGDDL+VTN KRL KGIE+ A N++L+K+NQIGT+TE +DA MA + Sbjct: 302 KRVGNKVQIVGDDLYVTNVKRLSKGIELKATNSILIKLNQIGTVTETLDAVEMAQKNNMT 361 Query: 364 VVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAG- 422 ++SHRSGE+ED IADLAVA NAG IKTG+ +RS+R AKYNQL+RIEEEL VA + G Sbjct: 362 AIISHRSGESEDTFIADLAVATNAGFIKTGSLSRSERIAKYNQLLRIEEELGKVAEFRGL 421 Query: 423 KNFRKV 428 K+F + Sbjct: 422 KSFYSI 427 >gb|AAD35958.1|AE001753_14 (AE001753) enolase [Thermotoga maritima] Length = 427 Score = 495 bits (1261), Expect = e-139 Identities = 266/426 (62%), Positives = 325/426 (75%), Gaps = 7/426 (1%) Query: 8 EIVAVIAREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRDGGK-RYHGK 65 EIV V ARE+LDSRGNPTVE +V +MGRA VPSGASTG EA+E+RD K RY GK Sbjct: 2 EIVDVRAREVLDSRGNPTVEAEVVLEDGTMGRAIVPSGASTGKFEALEIRDKDKKRYLGK 61 Query: 66 GVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 GV +AVENVN+ IAP L+GM+ Q +D+ LIELDGTENKS LGANAILAVS+AVA+AA Sbjct: 62 GVLKAVENVNETIAPALIGMNAFDQPLVDKTLIELDGTENKSKLGANAILAVSMAVARAA 121 Query: 126 ANALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWV 185 AN L LPLY+YLGGVNA VLPVPL NVINGG HA N+LD QEFMI+P G +SFREA+R Sbjct: 122 ANYLGLPLYKYLGGVNAKVLPVPLMNVINGGQHADNNLDLQEFMIVPAGFDSFREALRAG 181 Query: 186 SETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALA 245 +E +H LKK++ E + VGDEGGFAP + E + VLI+AIE+AGYKPGEE+ +A Sbjct: 182 AEIFHTLKKILHE--AGHVTAVGDEGGFAPNLSSNEEAIKVLIEAIEKAGYKPGEEVFIA 239 Query: 246 LDAASSEFYKD--GKYIVSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMIT 303 LD A+S FY + G Y V G+E + E L+ Y+EL + YPI+SIEDPF EEDW+ FV T Sbjct: 240 LDCAASSFYDEEKGVYYVDGEEKSSEVLMGYYEELVAKYPIISIEDPFAEEDWDAFVEFT 299 Query: 304 RELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYG 363 + +G KVQIVGDDL+VTN KRL KGIE+ A N++L+K+NQIGT+TE +DA MA + Sbjct: 300 KRVGNKVQIVGDDLYVTNVKRLSKGIELKATNSILIKLNQIGTVTETLDAVEMAQKNNMT 359 Query: 364 VVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAG- 422 ++SHRSGE+ED IADLAVA NAG IKTG+ +RS+R AKYNQL+RIEEEL VA + G Sbjct: 360 AIISHRSGESEDTFIADLAVATNAGFIKTGSLSRSERIAKYNQLLRIEEELGKVAEFRGL 419 Query: 423 KNFRKV 428 K+F + Sbjct: 420 KSFYSI 425 >sp|P96377|ENO_MYCTU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|7436874|pir||B70623 probable enolase - Mycobacterium tuberculosis (strain H37RV) >gi|1870005|emb|CAB06856.1| (Z92539) eno [Mycobacterium tuberculosis] Length = 429 Score = 488 bits (1244), Expect = e-137 Identities = 249/416 (59%), Positives = 315/416 (74%), Gaps = 4/416 (0%) Query: 9 IVAVIAREILDSRGNPTVEVDVHT-PISMGRAAVPSGASTGTHEAVELRDGGKRYHGKGV 67 I V AREILDSRGNPTVEV+V + RAAVPSGASTG HEAVELRDGG RY GKGV Sbjct: 4 IEQVRAREILDSRGNPTVEVEVALIDGTFARAAVPSGASTGEHEAVELRDGGDRYGGKGV 63 Query: 68 RRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAAN 127 ++AV+ V I P ++G++ QR +D+ L++LDGT +KS LG NAIL VSLAVAKAAA+ Sbjct: 64 QKAVQAVLDEIGPAVIGLNADDQRLVDQALVDLDGTPDKSRLGGNAILGVSLAVAKAAAD 123 Query: 128 ALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVSE 187 + ELPL++Y+GG NA++LPVP+ N++NGG HA +D QEFM+ PIGA SF EA+RW +E Sbjct: 124 SAELPLFRYVGGPNAHILPVPMMNILNGGAHADTAVDIQEFMVAPIGAPSFVEALRWGAE 183 Query: 188 TYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALALD 247 YH LK V+ +K G + +GDEGGFAP + T LD++ +AIE AG +PG ++ALALD Sbjct: 184 VYHALKSVL-KKEGLST-GLGDEGGFAPDVAGTTAALDLISRAIESAGLRPGADVALALD 241 Query: 248 AASSEFYKDGK-YIVSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMITREL 306 AA++EF+ DG Y+ G T +++ E Y L YP+VSIEDP E+DW+G+ +T + Sbjct: 242 AAATEFFTDGTGYVFEGTTRTADQMTEFYAGLLGAYPLVSIEDPLSEDDWDGWAALTASI 301 Query: 307 GKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYGVVV 366 G +VQIVGDD+FVTNP+RL++GIE G ANALL+KVNQIGTLTE +DA +A GY ++ Sbjct: 302 GDRVQIVGDDIFVTNPERLEEGIERGVANALLVKVNQIGTLTETLDAVTLAHHGGYRTMI 361 Query: 367 SHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAG 422 SHRSGETED IADLAVA+ +GQIKTGAPARS+R AKYNQL+RIEE L A YAG Sbjct: 362 SHRSGETEDTMIADLAVAIGSGQIKTGAPARSERVAKYNQLLRIEEALGDAARYAG 417 >emb|CAB94910.1| (AJ401152) enolase [Enterococcus faecalis] Length = 432 Score = 487 bits (1241), Expect = e-137 Identities = 253/421 (60%), Positives = 318/421 (75%), Gaps = 9/421 (2%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRDGGK-RYHGKG 66 I + ARE+LDSRGNPT+EV+V+T + GR VPSGASTG +EAVELRDG K RY GKG Sbjct: 4 ITDIYAREVLDSRGNPTIEVEVYTESGAFGRGMVPSGASTGEYEAVELRDGDKARYLGKG 63 Query: 67 VRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAA 126 V +AV+NVN IIA ++G DVR Q ID+ +I+LDGT NK LGANAIL VS+AVA+AAA Sbjct: 64 VTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIDLDGTPNKGKLGANAILGVSIAVARAAA 123 Query: 127 NALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVS 186 + LE+PLY YLGG N VLP P+ N+INGG HA N +DFQEFMIMP+GA +F+EA+R + Sbjct: 124 DYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSIDFQEFMIMPVGAPTFKEALRMGA 183 Query: 187 ETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALAL 246 E +H L ++ K A +VGDEGGFAP + E +V+I+AIE+AGY PG+++ LA+ Sbjct: 184 EVFHALASIL--KGRGLATSVGDEGGFAPNLGSNEEGFEVIIEAIEKAGYVPGKDVVLAM 241 Query: 247 DAASSEFY--KDGKYIVSGK---EYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVM 301 DAASSEFY + G Y+++ E T EE++ Y+EL S YPI+SIED E DW+GF Sbjct: 242 DAASSEFYDKEKGVYVLADSGEGEKTTEEMIAFYEELVSKYPIISIEDGLDENDWDGFKK 301 Query: 302 ITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAG 361 +T LG KVQ+VGDDLFVTN +L +GIE G AN++L+KVNQIGTLTE +A MA AG Sbjct: 302 LTEVLGDKVQLVGDDLFVTNTTKLAEGIEKGIANSILIKVNQIGTLTETFEAIEMAKEAG 361 Query: 362 YGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYA 421 Y VVSHRSGETED+TI+D+AVA NAGQIKTG+ +R+DR AKYNQL+RIE++L VA Y Sbjct: 362 YTAVVSHRSGETEDSTISDIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDQLGDVAEYK 421 Query: 422 G 422 G Sbjct: 422 G 422 >dbj|BAB07786.1| (AB046715) enolase [Desulfovibrio vulgaris] Length = 434 Score = 486 bits (1237), Expect = e-136 Identities = 253/418 (60%), Positives = 319/418 (75%), Gaps = 6/418 (1%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPIS-MGRAAVPSGASTGTHEAVELRDGGK-RYHGKG 66 IV+V AREILDSRGNPTVEV+V GRAAVPSGASTG+ EA+E+RDG K RY GKG Sbjct: 4 IVSVWAREILDSRGNPTVEVEVSLESGHTGRAAVPSGASTGSREALEMRDGDKGRYKGKG 63 Query: 67 VRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAA 126 V +AV+NV IA +VG+D Q ++D L++LDGT+NKS LGANA+L VSLA A+AA+ Sbjct: 64 VEKAVDNVMGEIAEAIVGLDSLRQVQVDNTLLDLDGTDNKSRLGANAMLGVSLATARAAS 123 Query: 127 NALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVS 186 + L LPLYQYLGGVNA VLPVPL N+INGG HA N+LD QEFMIMPIGA +FR+A+R + Sbjct: 124 SFLGLPLYQYLGGVNAKVLPVPLMNIINGGAHAPNNLDIQEFMIMPIGAATFRDALRMGA 183 Query: 187 ETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALAL 246 ET+H LK ++A + +VGDEGGFAP +K E ++KAIEEAGY PG EIALA+ Sbjct: 184 ETFHTLKALLAAD--GHVTSVGDEGGFAPNLKNHDEAFRYIMKAIEEAGYIPGAEIALAI 241 Query: 247 DAASSEFYKDGKYIVSG--KEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMITR 304 DAA+SEF+KDGKY+++G K + E++E E T+ YP++SIED E DW+G+ +T Sbjct: 242 DAAASEFHKDGKYVLAGEGKNLSNSEMVEWLGEFTTRYPLISIEDGLAEADWDGWRELTY 301 Query: 305 ELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYGV 364 +LG +Q+VGDD+FVTNP L +GI+ G AN++L+K+NQIGTLTE +D MA +A Y Sbjct: 302 KLGDTIQLVGDDIFVTNPDILAEGIDEGVANSILIKLNQIGTLTETLDTIEMAKQAAYTT 361 Query: 365 VVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAG 422 V+SHRSGETED I+DLAV LNAGQIKTG+ RSDR AKYNQL+RIEE+L+ +Y G Sbjct: 362 VISHRSGETEDHFISDLAVGLNAGQIKTGSLCRSDRLAKYNQLLRIEEDLDDTGIYFG 419 >pir||A81841 phosphopyruvate hydratase (EC 4.2.1.11) NMA1495 [imported] - Neisseria meningitidis (group A strain Z2491) >gi|7380143|emb|CAB84728.1| (AL162756) enolase [Neisseria meningitidis Z2491] Length = 428 Score = 481 bits (1225), Expect = e-135 Identities = 259/419 (61%), Positives = 306/419 (72%), Gaps = 6/419 (1%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPIS-MGRAAVPSGASTGTHEAVELRDGGK-RYHGKG 66 IV + AREILDSRGNPTVE DV MGRAAVPSGASTG EA+ELRDG K RY GKG Sbjct: 4 IVDIFAREILDSRGNPTVECDVLLESGVMGRAAVPSGASTGQKEALELRDGDKSRYSGKG 63 Query: 67 VRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAA 126 V +AVE+VN IA L+G+D Q ID+++IELDGTENK NLGANA LAVS+AVA+AAA Sbjct: 64 VLKAVEHVNNQIAQALIGIDANEQSYIDQIMIELDGTENKGNLGANATLAVSMAVARAAA 123 Query: 127 NALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVS 186 LPLY+YLGG LPVP+ NVINGG HA N L+ QEFMIMP+GA SFREA+R + Sbjct: 124 EDSGLPLYRYLGGAGPMSLPVPMMNVINGGEHANNSLNIQEFMIMPVGAKSFREALRCGA 183 Query: 187 ETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALAL 246 E +H LKK+ K VGDEGGFAP + E L ++++A E AGYK GE++ AL Sbjct: 184 EIFHALKKLCDSK--GFPTTVGDEGGFAPNLNSHKEALQLMVEATEAAGYKAGEDVLFAL 241 Query: 247 DAASSEFYKDGKYIVS--GKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMITR 304 D ASSEFYKDGKY + G+ YT E E + L + +PI+SIED E DWEG+ ++T Sbjct: 242 DCASSEFYKDGKYHLEAEGRSYTNAEFAEYLEGLVNEFPIISIEDGMDENDWEGWKLLTE 301 Query: 305 ELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYGV 364 +LG KVQ+VGDDLFVTNPK L +GIE G ANALL+KVNQIGTL+E + A +A R Y Sbjct: 302 KLGGKVQLVGDDLFVTNPKILAEGIEKGVANALLVKVNQIGTLSETLKAVDLAKRNRYAS 361 Query: 365 VVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAGK 423 V+SHRSGETED+TIADLAVA N QIKTG+ +RSDR AKYNQL+RIEEEL A Y K Sbjct: 362 VMSHRSGETEDSTIADLAVATNCMQIKTGSLSRSDRMAKYNQLLRIEEELAEAADYPSK 420 >pir||D81100 enolase NMB1285 [imported] - Neisseria meningitidis (group B strain MD58) >gi|7226525|gb|AAF41661.1| (AE002477) enolase [Neisseria meningitidis MC58] Length = 428 Score = 480 bits (1222), Expect = e-134 Identities = 258/419 (61%), Positives = 306/419 (72%), Gaps = 6/419 (1%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPIS-MGRAAVPSGASTGTHEAVELRDGGK-RYHGKG 66 IV + AREILDSRGNPTVE DV MGRAAVPSGASTG EA+ELRDG K RY GKG Sbjct: 4 IVDIFAREILDSRGNPTVECDVLLESGVMGRAAVPSGASTGQKEALELRDGDKSRYSGKG 63 Query: 67 VRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAA 126 V +AVE+VN IA L+G+D Q ID+++IELDGTENK NLGANA LAVS+AVA+AAA Sbjct: 64 VLKAVEHVNNQIAQALIGIDANEQSYIDQIMIELDGTENKGNLGANATLAVSMAVARAAA 123 Query: 127 NALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVS 186 LPLY+YLGG LPVP+ NVINGG HA N L+ QEFMIMP+GA SFREA+R + Sbjct: 124 EDSGLPLYRYLGGAGPMSLPVPMMNVINGGEHANNSLNIQEFMIMPVGAKSFREALRCGA 183 Query: 187 ETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALAL 246 E +H LKK+ K VGDEGGFAP + E L ++++A E AGYK GE++ AL Sbjct: 184 EIFHALKKLCDSK--GFPTTVGDEGGFAPNLNSHKEALQLMVEATEAAGYKAGEDVLFAL 241 Query: 247 DAASSEFYKDGKYIVS--GKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMITR 304 D ASSEFYKDGKY + G+ YT E E + L + +PI+SIED E DWEG+ ++T Sbjct: 242 DCASSEFYKDGKYHLEAEGRSYTNAEFAEYLEGLVNEFPIISIEDGMDENDWEGWKLLTE 301 Query: 305 ELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYGV 364 +LG +VQ+VGDDLFVTNPK L +GIE G ANALL+KVNQIGTL+E + A +A R Y Sbjct: 302 KLGGRVQLVGDDLFVTNPKILAEGIEKGVANALLVKVNQIGTLSETLKAVDLAKRNRYAS 361 Query: 365 VVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAGK 423 V+SHRSGETED+TIADLAVA N QIKTG+ +RSDR AKYNQL+RIEEEL A Y K Sbjct: 362 VMSHRSGETEDSTIADLAVATNCMQIKTGSLSRSDRMAKYNQLLRIEEELAEAADYPSK 420 >sp|O51312|ENO_BORBU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|7436876|pir||H70141 enolase (eno) homolog - Lyme disease spirochete >gi|2688240|gb|AAC66719.1| (AE001140) enolase (eno) [Borrelia burgdorferi] Length = 433 Score = 474 bits (1208), Expect = e-133 Identities = 251/425 (59%), Positives = 314/425 (73%), Gaps = 9/425 (2%) Query: 7 YEIVAVIAREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRDGGKR-YHG 64 + I + AR+I+DSRGNPTVE DV + GRAAVPSGASTG +EAVELRDG K Y G Sbjct: 3 FHIYEIKARQIIDSRGNPTVEADVILEDGTYGRAAVPSGASTGINEAVELRDGDKSVYMG 62 Query: 65 KGVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKA 124 KGV +A+EN+ IIAPEL GM Q IDR ++ELDGT K LGANAILAVS+A AKA Sbjct: 63 KGVLKAIENIKNIIAPELEGMSALNQVAIDRKMLELDGTPTKEKLGANAILAVSMATAKA 122 Query: 125 AANALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRW 184 AA L L YQYLG A +LP P+ N+INGG H+ N +DFQEFMIMPIGA +F EAIR Sbjct: 123 AAKYLGLRPYQYLGAYKANILPTPMCNIINGGAHSDNSVDFQEFMIMPIGAKTFSEAIRM 182 Query: 185 VSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIAL 244 +E +H LK +++ K A +VGDEGGFAP +K E +V+I+AI++AGY+PG++IA+ Sbjct: 183 AAEVFHTLKGILSGK--GYATSVGDEGGFAPNLKSNEEACEVIIEAIKKAGYEPGKDIAI 240 Query: 245 ALDAASSEFY--KDGKYIV---SGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGF 299 ALD A+SE Y K KY++ + ++ T E+++E + + YPI+SIED EEDW+G+ Sbjct: 241 ALDPATSELYDPKTKKYVLKWSTKEKLTSEQMVEYWAKWVEKYPIISIEDGMAEEDWDGW 300 Query: 300 VMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFR 359 +T ++G K+Q+VGDDLFVTN LKKGIEMG AN++L+KVNQIGTLTE +A MA + Sbjct: 301 KKLTDKIGNKIQLVGDDLFVTNTSFLKKGIEMGVANSILIKVNQIGTLTETFEAVEMAKK 360 Query: 360 AGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAV 419 AGY +VSHRSGETED TIADL VAL GQIKTG+ +R+DR AKYNQLIRIEEELE A Sbjct: 361 AGYTAIVSHRSGETEDTTIADLVVALGTGQIKTGSLSRTDRIAKYNQLIRIEEELETTAE 420 Query: 420 YAGKN 424 Y GK+ Sbjct: 421 YHGKS 425 >sp|P42894|ENO_NEOFR ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|515827|emb|CAA56645.1| (X80474) enolase [Neocallimastix frontalis] Length = 436 Score = 474 bits (1206), Expect = e-132 Identities = 258/436 (59%), Positives = 316/436 (72%), Gaps = 17/436 (3%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGKR-YHGKGV 67 I V AR+I DSRGNPTVEV+V T + RAAVPSGASTG HEA+ELRDG K Y GKGV Sbjct: 3 ITKVHARQIFDSRGNPTVEVEVTTDKGLFRAAVPSGASTGVHEALELRDGIKADYVGKGV 62 Query: 68 RRAVENVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 +AVENVNK IAP LV +DV+ Q+ +D L++LDGT NKS LGANAIL VSLAVA+A Sbjct: 63 LKAVENVNKTIAPALVAANLDVKNQKAVDDFLLKLDGTPNKSKLGANAILGVSLAVARAG 122 Query: 126 ANALELPLYQYLGGV----NAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREA 181 A +PLYQ+LG + ++LPVP NV+NGG HAGN L QEFMI+P GA SF EA Sbjct: 123 AADKGVPLYQHLGELAGNKGPWILPVPSMNVLNGGSHAGNKLAMQEFMILPTGAKSFTEA 182 Query: 182 IRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEE 241 ++ SE YH LK VI KYG++A NVGDEGGFAP +++ E L++L +AI +AGY + Sbjct: 183 LKMGSEVYHALKSVIKAKYGQDACNVGDEGGFAPNIQDNKEGLELLNEAIAKAGYTG--K 240 Query: 242 IALALDAASSEFYKDGKYIVSGKE--------YTREELLELYKELTSTYPIVSIEDPFHE 293 + + +D ASSEFYKDGKY + K + EEL + YKE+TS YPIVSIEDP+ + Sbjct: 241 VKIGMDVASSEFYKDGKYDLDFKNPNSDPSKWISGEELGQFYKEITSEYPIVSIEDPYDQ 300 Query: 294 EDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDA 353 +D+E + ++ K+QIVGDDL VTNPKR+ IE A N LLLKVNQIGT++E++ A Sbjct: 301 DDFESWSKFRADMQDKIQIVGDDLTVTNPKRIAMAIEKKACNGLLLKVNQIGTVSESIQA 360 Query: 354 AYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEE 413 A AF G+GV+VSHRSGETED IADL V L +GQIKTGAP RS+R AKYNQL+RIEEE Sbjct: 361 ALDAFNDGWGVMVSHRSGETEDTFIADLVVGLKSGQIKTGAPCRSERLAKYNQLLRIEEE 420 Query: 414 LEGVAVYAGKNFRKVF 429 L A YAG+NFR+ F Sbjct: 421 LGANATYAGENFRRPF 436 >pir||T12341 phosphopyruvate hydratase (EC 4.2.1.11) - common ice plant >gi|533474|gb|AAA21277.1| (U09194) 2-phospho-D-glycerate hydrolase [Mesembryanthemum crystallinum] Length = 444 Score = 473 bits (1205), Expect = e-132 Identities = 258/438 (58%), Positives = 318/438 (71%), Gaps = 21/438 (4%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRDGGKRYHGKGV 67 I V AR+I DSRGNPTVE D+H + RAAVPSGASTG +EA+ELRDGGK Y GKGV Sbjct: 4 IKCVKARQIYDSRGNPTVEADIHLDDGTYARAAVPSGASTGVYEALELRDGGKDYMGKGV 63 Query: 68 RRAVENVNKIIAPELVGMDVRWQREIDRLLIE-LDGTEN-----KSNLGANAILAVSLAV 121 +AV+NVN+II P LVG D Q ID +++ LDGT N K LGANAILAVSLAV Sbjct: 64 YKAVKNVNEIIGPALVGKDPTQQTAIDNFMVQQLDGTVNEWGWCKQKLGANAILAVSLAV 123 Query: 122 AKAAANALELPLYQYLG---GVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSF 178 KA A ++PLYQ++ G VLPVP NVINGG HAGN L QEFMI+P GA+SF Sbjct: 124 CKAGAQVKKIPLYQHIAEIAGNKNMVLPVPAFNVINGGSHAGNKLAMQEFMILPTGASSF 183 Query: 179 REAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKP 238 +EA++ SE YH LK VI +KYG++A NVGDEGGFAP ++E E L++L AIE+AGY Sbjct: 184 KEAMKMGSEVYHNLKSVIKKKYGQDATNVGDEGGFAPNIQENKEGLELLKTAIEKAGYTG 243 Query: 239 GEEIALALDAASSEFYKDGK-YIVSGKEYTR--------EELLELYKELTSTYPIVSIED 289 ++ + +D A+SEFYK+ K Y ++ KE E L +LYK + YPIVSIED Sbjct: 244 --KVVIGMDVAASEFYKEDKSYDLNFKEENNDGSQRISGEALKDLYKSFVAEYPIVSIED 301 Query: 290 PFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTE 349 PF ++DWE + +T E G+KVQIVGDDL VTNPKR+KK I+ + NALLLKVNQIG++TE Sbjct: 302 PFDQDDWEHYAKMTAECGEKVQIVGDDLLVTNPKRVKKAIDENSCNALLLKVNQIGSVTE 361 Query: 350 AMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIR 409 +++A M+ +AG+GV+ SHRSGETED IADL+V L+ GQIKTGAP RS+R AKYNQL+R Sbjct: 362 SIEAVKMSKKAGWGVMASHRSGETEDTFIADLSVGLSTGQIKTGAPCRSERLAKYNQLLR 421 Query: 410 IEEELEGVAVYAGKNFRK 427 IEEEL AVYAG NFR+ Sbjct: 422 IEEELGDKAVYAGANFRR 439 >sp|Q43130|ENO_MESCR ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|1087071|gb|AAB34986.1| (S79242) 2-phospho-D-glycerate hydrolase, enolase {EC 4.2.1.11} [Mesembryanthemum crystallinum=common ice plant, Peptide, 444 aa] Length = 444 Score = 473 bits (1203), Expect = e-132 Identities = 258/438 (58%), Positives = 317/438 (71%), Gaps = 21/438 (4%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRDGGKRYHGKGV 67 I V AR+I DSRGNPTVE D+H + RAAVPSGASTG +EA+ELRDGGK Y GKGV Sbjct: 4 IKCVKARQIYDSRGNPTVEADIHLDDGTYARAAVPSGASTGVYEALELRDGGKDYMGKGV 63 Query: 68 RRAVENVNKIIAPELVGMDVRWQREIDRLLIE-LDGTEN-----KSNLGANAILAVSLAV 121 +AV+NVN+II P LVG D Q ID +++ LDGT N K LGANAILAVSLAV Sbjct: 64 YKAVKNVNEIIGPALVGKDPTQQTAIDNFMVQQLDGTVNEWGWCKQKLGANAILAVSLAV 123 Query: 122 AKAAANALELPLYQYLG---GVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSF 178 KA A ++PLYQ++ G VLPVP NVINGG HAGN L QEFMI+P GA+SF Sbjct: 124 CKAGAQVKKIPLYQHIAEIAGNKNMVLPVPAFNVINGGSHAGNKLAMQEFMILPTGASSF 183 Query: 179 REAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKP 238 +EA++ SE YH LK VI +KYG++A NVGDEGGFAP ++E E L++L AIE+AGY Sbjct: 184 KEAMKMGSEVYHNLKSVIKKKYGQDATNVGDEGGFAPNIQENKEGLELLKTAIEKAGYTG 243 Query: 239 GEEIALALDAASSEFYKDGK-YIVSGKEYTR--------EELLELYKELTSTYPIVSIED 289 ++ + +D A+SEFYK+ K Y ++ KE E L +LYK + YPIVSIED Sbjct: 244 --KVVIGMDVAASEFYKEDKSYDLNFKEENNDGSQRISGEALKDLYKSFVAEYPIVSIED 301 Query: 290 PFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTE 349 PF ++DWE + +T E G+KVQIVGDDL VTNPKR+KK I+ NALLLKVNQIG++TE Sbjct: 302 PFDQDDWEHYAKMTAECGEKVQIVGDDLLVTNPKRVKKAIDENPCNALLLKVNQIGSVTE 361 Query: 350 AMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIR 409 +++A M+ +AG+GV+ SHRSGETED IADL+V L+ GQIKTGAP RS+R AKYNQL+R Sbjct: 362 SIEAVKMSKKAGWGVMASHRSGETEDTFIADLSVGLSTGQIKTGAPCRSERLAKYNQLLR 421 Query: 410 IEEELEGVAVYAGKNFRK 427 IEEEL AVYAG NFR+ Sbjct: 422 IEEELGDKAVYAGANFRR 439 >gb|AAC46289.1| (AF000366) enolase homolog [Borrelia burgdorferi] Length = 433 Score = 473 bits (1203), Expect = e-132 Identities = 250/425 (58%), Positives = 313/425 (72%), Gaps = 9/425 (2%) Query: 7 YEIVAVIAREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRDGGKR-YHG 64 + I + AR+I+DSRGNPTVE DV + GRAAVPSGASTG +EAVELRDG K Y G Sbjct: 3 FHIYEIKARQIIDSRGNPTVEADVILEDGTYGRAAVPSGASTGINEAVELRDGDKSVYMG 62 Query: 65 KGVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKA 124 KGV +A+EN+ IIAPEL GM Q IDR ++ELDGT K LGANAILAVS+A AKA Sbjct: 63 KGVLKAIENIKNIIAPELEGMSALNQVAIDRKMLELDGTPTKEKLGANAILAVSMATAKA 122 Query: 125 AANALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRW 184 AA L L YQYLG A +LP P+ N+INGG H+ N +DFQEFMIMPIGA +F EAIR Sbjct: 123 AAKYLGLRPYQYLGAYKANILPTPMCNIINGGAHSDNSVDFQEFMIMPIGAKTFSEAIRM 182 Query: 185 VSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIAL 244 +E +H LK +++ K A +VGDEGGFAP +K E +V+I+AI++AGY+PG++IA+ Sbjct: 183 AAEVFHTLKGILSGK--GYATSVGDEGGFAPNLKSNEEACEVIIEAIKKAGYEPGKDIAI 240 Query: 245 ALDAASSEFY--KDGKYIV---SGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGF 299 ALD A+SE Y K KY++ + ++ T E+++E + + YPI+SIED EEDW+G+ Sbjct: 241 ALDPATSELYDPKTKKYVLKWSTKEKLTSEQMVEYWAKWVEKYPIISIEDGMAEEDWDGW 300 Query: 300 VMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFR 359 +T ++G K+Q+VGDDLFVTN LKKGIEMG AN++L+KVNQIGTLTE +A MA + Sbjct: 301 KKLTDKIGNKIQLVGDDLFVTNTSFLKKGIEMGVANSILIKVNQIGTLTETFEAVEMAKK 360 Query: 360 AGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAV 419 AGY +VSHRSGETED TIADL VAL GQ KTG+ +R+DR AKYNQLIRIEEELE A Sbjct: 361 AGYTAIVSHRSGETEDTTIADLVVALGTGQTKTGSLSRTDRIAKYNQLIRIEEELETTAE 420 Query: 420 YAGKN 424 Y GK+ Sbjct: 421 YHGKS 425 >emb|CAB75428.1| (AJ271785) enolase [Lupinus luteus] Length = 444 Score = 473 bits (1203), Expect = e-132 Identities = 257/437 (58%), Positives = 322/437 (72%), Gaps = 21/437 (4%) Query: 9 IVAVIAREILDSRGNPTVEVDVH-TPISMGRAAVPSGASTGTHEAVELRDGGKRYHGKGV 67 I + AR+I DSRGNPTVEVD+ + + RAAVPSGASTG +EA+ELRDGG Y GKGV Sbjct: 4 IATIKARQIFDSRGNPTVEVDLTLSDGTFARAAVPSGASTGIYEALELRDGGSDYLGKGV 63 Query: 68 RRAVENVNKIIAPELVGMDVRWQREIDRLLI-ELDGTEN-----KSNLGANAILAVSLAV 121 +AV+NVN IIAP L+G D Q ID ++ ELDGT N K LGANAILAVSLAV Sbjct: 64 SKAVDNVNTIIAPALIGKDPTEQTAIDNFIVQELDGTVNEWGWGKQKLGANAILAVSLAV 123 Query: 122 AKAAANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSF 178 KA A+AL++PLY++ L G VLPVP NVINGG HAGN L QEFMI+P+GA++F Sbjct: 124 CKAGASALKIPLYKHIANLAGNKNLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASTF 183 Query: 179 REAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKP 238 +EA++ E YH LK VI +KYG++AVNVGDEGGFAP ++E E L++L AI +AGY Sbjct: 184 KEALKIGVEVYHNLKSVIKKKYGQDAVNVGDEGGFAPNIQENKEGLELLKSAIAKAGYT- 242 Query: 239 GEEIALALDAASSEFY-KDGKYIVSGKE--------YTREELLELYKELTSTYPIVSIED 289 +++ + +D A+SEFY D KY+++ KE + EEL ELYK + YPI SIED Sbjct: 243 -DKVVIGMDVAASEFYTSDKKYVLNFKEDNNDGSQKISGEELKELYKSFVAEYPIASIED 301 Query: 290 PFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTE 349 PF ++DWE + IT E+G +VQIVGDDL VTNPKR++K I+ + NALLLKVNQIG++TE Sbjct: 302 PFDQDDWEHYGKITTEIGTEVQIVGDDLLVTNPKRVQKAIDSKSCNALLLKVNQIGSVTE 361 Query: 350 AMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIR 409 +++A M+ +AG+GV+ SHRSGETED IADLAV L+ GQIKTGAP RS+R AKYNQL+R Sbjct: 362 SIEAVKMSKKAGWGVMTSHRSGETEDTFIADLAVGLSTGQIKTGAPCRSERLAKYNQLLR 421 Query: 410 IEEELEGVAVYAGKNFR 426 IEEEL AVYAG N+R Sbjct: 422 IEEELGDEAVYAGVNYR 438 >emb|CAB96173.1| (AJ271719) enolase [Spinacia oleracea] Length = 444 Score = 469 bits (1193), Expect = e-131 Identities = 256/437 (58%), Positives = 317/437 (71%), Gaps = 21/437 (4%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRDGGKRYHGKGV 67 I +V AR+I DSRGNPTVE D+H + RAAVPSGASTG +EA+ELRDGGK Y GKGV Sbjct: 4 IKSVKARQIFDSRGNPTVEADIHLDDGTFARAAVPSGASTGIYEALELRDGGKDYMGKGV 63 Query: 68 RRAVENVNKIIAPELVGMDVRWQREIDRLLI-ELDGTEN-----KSNLGANAILAVSLAV 121 +AV+NVN+II P LVG D Q ID ++ ELDGT N K LGANAILAVSLAV Sbjct: 64 FKAVQNVNEIIGPALVGKDPTEQTAIDNFMVQELDGTTNEWGWCKQKLGANAILAVSLAV 123 Query: 122 AKAAANALELPLYQYLGGVNA---YVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSF 178 KA A ++PLYQ++ ++ VLPVP NVINGG HAGN L QEFMI+P GA+SF Sbjct: 124 CKAGAQVKKIPLYQHIAEISGNKKMVLPVPAFNVINGGSHAGNKLAMQEFMILPTGASSF 183 Query: 179 REAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKP 238 REA++ SE YH LK VI +KYG++A NVGDEGGFAP ++E E L++L AIE+AGY Sbjct: 184 REAMKMGSEVYHHLKSVIKKKYGQDATNVGDEGGFAPNIQENKEGLELLKTAIEKAGYTG 243 Query: 239 GEEIALALDAASSEFY-KDGKYIVSGKEYTRE--------ELLELYKELTSTYPIVSIED 289 ++ + +D A++EFY KD Y ++ KE + L +LYK S YPIVSIED Sbjct: 244 --KVVIGMDVAAAEFYSKDKTYDLNFKEENNDGSQKISGDALKDLYKSFVSEYPIVSIED 301 Query: 290 PFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTE 349 PF ++DWE + +T E+G KVQIVGDDL VTNPKR++K I + NALLLKVNQIG++TE Sbjct: 302 PFDQDDWEHYGKLTAEIGDKVQIVGDDLLVTNPKRVEKAINGKSCNALLLKVNQIGSVTE 361 Query: 350 AMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIR 409 +++A M+ RAG+GV+ SHRSGETED IADL+V L+ GQIKTGAP RS+R AKYNQL+R Sbjct: 362 SIEAVKMSKRAGWGVMASHRSGETEDTFIADLSVGLSTGQIKTGAPCRSERLAKYNQLLR 421 Query: 410 IEEELEGVAVYAGKNFR 426 IEEEL A+YAG +FR Sbjct: 422 IEEELGDKAIYAGADFR 438 >sp|P77972|ENO_SYNY3 ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|7436879|pir||S76837 phosphopyruvate hydratase (EC 4.2.1.11) - Synechocystis sp. (strain PCC 6803) >gi|1653839|dbj|BAA18749.1| (D90917) enolase [Synechocystis sp.] Length = 432 Score = 468 bits (1191), Expect = e-131 Identities = 244/425 (57%), Positives = 310/425 (72%), Gaps = 3/425 (0%) Query: 1 MTMENPYEIVAVIAREILDSRGNPTVEVDVHTPISM-GRAAVPSGASTGTHEAVELRDGG 59 M + P I + AREILDSRG PT+E +V G A VPSGASTG+ EA ELRDG Sbjct: 1 MLSKVPATIEEIAAREILDSRGRPTIEAEVRLESGAHGIAQVPSGASTGSFEAHELRDGD 60 Query: 60 -KRYHGKGVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVS 118 KRY GKGV +AV NV + IAP + G+D Q +D+ +I+ DGT+NK LGANAIL VS Sbjct: 61 PKRYDGKGVEKAVRNVTEKIAPVVEGLDAFDQMAVDQAMIDRDGTDNKKELGANAILGVS 120 Query: 119 LAVAKAAANALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSF 178 LA AKAAA L +PLY+YLGG A VLPVP+ NVINGG HA N++DFQEFMIMP+GA +F Sbjct: 121 LATAKAAAAELAIPLYRYLGGPLANVLPVPMMNVINGGAHADNNVDFQEFMIMPVGAETF 180 Query: 179 REAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKP 238 +EA+RW +E + VL KV+ E+ + VGDEGG+AP + + LD+LI+AIE+AGYKP Sbjct: 181 KEALRWGAEVFAVLGKVLKERKLLSG-GVGDEGGYAPNLTSNQQALDILIEAIEQAGYKP 239 Query: 239 GEEIALALDAASSEFYKDGKYIVSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEG 298 G +IALA+D A+SEF+K+G+Y G ++ +E ++ +L S YPIVSIED HE+DWE Sbjct: 240 GSQIALAMDIAASEFFKNGQYEYDGGSHSPQEFIDYQAKLVSQYPIVSIEDGLHEDDWES 299 Query: 299 FVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAF 358 + +T LG K Q+VGDDL VTNP RL+K I++G ANA+L+K+NQIGTL+E ++ +A Sbjct: 300 WKGLTTSLGTKTQLVGDDLMVTNPVRLQKSIDLGVANAILIKLNQIGTLSETLETISLAT 359 Query: 359 RAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVA 418 R Y V+SHRSGETED TIADLAVA GQIKTG+ RS+R AKYN+L+RIE+EL A Sbjct: 360 RHSYRSVISHRSGETEDTTIADLAVATRVGQIKTGSLCRSERVAKYNRLLRIEDELGDRA 419 Query: 419 VYAGK 423 VYA K Sbjct: 420 VYAPK 424 >sp|P74934|ENO_TREPA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|7436871|pir||F71278 probable enolase (eno) - syphilis spirochete >gi|1575361|gb|AAB39979.1| (U61534) 2-phospho-D-glycerate hydrolase [Treponema pallidum] >gi|3323125|gb|AAC65781.1| (AE001252) enolase (eno) [Treponema pallidum] Length = 432 Score = 467 bits (1190), Expect = e-131 Identities = 250/430 (58%), Positives = 320/430 (74%), Gaps = 13/430 (3%) Query: 8 EIVAVIAREILDSRGNPTVEVDVH-TPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGK 65 +I + AREI+DSRGNPTVEVDV + S GRA VPSGASTG EA+E+RDG K RY+GK Sbjct: 3 DIACIEAREIIDSRGNPTVEVDVSLSDGSFGRACVPSGASTGEFEALEMRDGDKERYNGK 62 Query: 66 GVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 GV +AV VN +IA L GMD Q EID + LDGT+NKS LGANA+L VS+A A+AA Sbjct: 63 GVLKAVGTVNTLIADTLEGMDALNQGEIDHAMRNLDGTDNKSKLGANAMLGVSMACARAA 122 Query: 126 ANALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWV 185 A+ L +PLY+YLGGV+ + +PVP++N+INGG H+ N +DFQEFM+MPIGA S REA+R Sbjct: 123 ADFLGVPLYRYLGGVHTFRMPVPMANIINGGKHSDNKIDFQEFMVMPIGAASMREAVRMT 182 Query: 186 SETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALA 245 +E +H LK ++A GK A +VGDEGGFAP + + L+ ++KAI +AG P +++ +A Sbjct: 183 AEVFHALKGLLAAD-GK-ATSVGDEGGFAPDLDN-EQALEYIMKAIAKAGLAPRKDVCIA 239 Query: 246 LDAASSEFYKDG-----KYIVS--GKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEG 298 LD ASSE + +G K+ S GK +T +E+++LYK+ +TYPIVSIEDP + DW G Sbjct: 240 LDCASSELFDEGDRRGYKFWKSNPGKLFTAQEMIDLYKKWIATYPIVSIEDPLDQNDWAG 299 Query: 299 FVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAF 358 +V +T+ELG KVQIVGDD FVTN RL +GI+ G+ N++L+K+NQIGT+TE +DA MA Sbjct: 300 YVQLTKELGDKVQIVGDDFFVTNTGRLARGIKEGSCNSILIKLNQIGTVTETVDAVRMAQ 359 Query: 359 RAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVA 418 AGY V+SHRSGETEDA IADLAVAL GQIKTG+ +RSDR AKYNQL+RIEEEL A Sbjct: 360 NAGYAAVISHRSGETEDAFIADLAVALETGQIKTGSMSRSDRVAKYNQLMRIEEELGAQA 419 Query: 419 VYAG-KNFRK 427 Y G K F + Sbjct: 420 RYYGAKTFER 429 >sp|O69174|ENO_STAAU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (LAMININ BINDING PROTEIN) >gi|11268974|pir||T47276 phosphopyruvate hydratase (EC 4.2.1.11) [imported] - Staphylococcus aureus >gi|3152725|gb|AAC17130.1| (AF065394) enolase [Staphylococcus aureus] Length = 434 Score = 466 bits (1187), Expect = e-130 Identities = 245/424 (57%), Positives = 311/424 (72%), Gaps = 12/424 (2%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRDGGK-RYHGKG 66 I V ARE+LDSRGNPTVEV+V T + GRA VPSGASTG HEAVELRDG K RY GKG Sbjct: 4 ITDVYAREVLDSRGNPTVEVEVLTESGAFGRALVPSGASTGEHEAVELRDGDKSRYLGKG 63 Query: 67 VRRAVENVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKA 124 V +AVENVN+IIAPE++ V Q ID+++I LDGT NK LGANAIL VS+AVA+A Sbjct: 64 VTKAVENVNEIIAPEIIEGEFSVLDQVSIDKMMIALDGTPNKGKLGANAILGVSIAVARA 123 Query: 125 AANALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRW 184 AA+ L PLY+YLGG N LPVP+ N++NGG H+ + FQEFMI+P+GA +F+E++RW Sbjct: 124 AADLLGQPLYKYLGGFNGKQLPVPMMNIVNGGSHSDAPIAFQEFMILPVGATTFKESLRW 183 Query: 185 VSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIAL 244 +E +H LK +++++ + AV GDEGGFAP + + ++ +I+AIE AGYKPGEE+ L Sbjct: 184 GTEIFHNLKSILSQRGLETAV--GDEGGFAPKFEGTEDAVETIIQAIEAAGYKPGEEVFL 241 Query: 245 ALDAASSEFYKDGKYIVS------GKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEG 298 D ASSEFY++G Y S G + T E ++ ++L YPI++IED E DW+G Sbjct: 242 GFDCASSEFYENGVYDYSKFEGEHGAKRTAAEQVDYLEQLVDKYPIITIEDGMDENDWDG 301 Query: 299 FVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAF 358 + +T +G +VQ+VGDDLFVTN + L KGIE G N++L+KVNQIGTLTE DA MA Sbjct: 302 WKQLTERIGDRVQLVGDDLFVTNTEILAKGIENGIGNSILIKVNQIGTLTETFDAIEMAQ 361 Query: 359 RAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVA 418 +AGY VVSHRSGETED TIAD+AVA NAGQIKTG+ +R+DR AKYNQL+RIE+EL A Sbjct: 362 KAGYTAVVSHRSGETEDTTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDELFETA 421 Query: 419 VYAG 422 Y G Sbjct: 422 KYDG 425 >sp|P07323|ENOG_RAT GAMMA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (NEURAL ENOLASE) (NSE) >gi|92215|pir||A24742 phosphopyruvate hydratase (EC 4.2.1.11) gamma - rat >gi|204042|gb|AAA41119.1| (M11931) neuron-specific enolase [Rattus norvegicus] >gi|1619609|emb|CAA30556.1| (X07727) enol_cds [Rattus norvegicus] >gi|2465396|gb|AAB72088.1| (AF019973) neuron-specific enolase [Rattus norvegicus] >gi|225406|prf||1302225A enolase gamma,neuron specific [Rattus norvegicus] Length = 434 Score = 466 bits (1186), Expect = e-130 Identities = 250/431 (58%), Positives = 315/431 (73%), Gaps = 17/431 (3%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67 I + AREILDSRGNPTVEVD+HT + RAAVPSGASTG +EA+ELRDG K RY GKGV Sbjct: 3 IQKIWAREILDSRGNPTVEVDLHTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGV 62 Query: 68 RRAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 +AV+++N IAP L+ G+ V Q ++D L++ELDGTENKS GANAIL VSLAV KA Sbjct: 63 LKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAG 122 Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182 A +LPLY++ L G + +LPVP NVINGG HAGN L QEFMI+P+GA SFR+A+ Sbjct: 123 AAEKDLPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAM 182 Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242 R +E YH LK VI +KYGK+A NVGDEGGFAP + E +E L+++ +AI++AGY E++ Sbjct: 183 RLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYT--EKM 240 Query: 243 ALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEED 295 + +D A+SEFY+DGKY + K T ++L LY++ YP+VSIEDPF ++D Sbjct: 241 VIGMDVAASEFYRDGKYDLDFKSPADPSRCITGDQLGALYQDFVRNYPVVSIEDPFDQDD 300 Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355 W + T +G +QIVGDDL VTNPKR+++ +E A N LLLKVNQIG++TEA+ A Sbjct: 301 WAAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACK 358 Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415 +A G+GV+VSHRSGETED IADL V L GQIKTGAP RS+R AKYNQL+RIEEEL Sbjct: 359 LAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELG 418 Query: 416 GVAVYAGKNFR 426 A +AG NFR Sbjct: 419 EEARFAGHNFR 429 >gi|5803011 enolase 2, (gamma, neuronal); Enolase-2, gamma, neuronal [Homo sapiens] >gi|11436317|ref|XP_006974.1| enolase 2, (gamma, neuronal) [Homo sapiens] >gi|68305|pir||NOHUG phosphopyruvate hydratase (EC 4.2.1.11) gamma - human >gi|31165|emb|CAA36215.1| (X51956) human gamma enolase [Homo sapiens] >gi|182116|gb|AAB59554.1| (M22349) enolase [Homo sapiens] >gi|1732416|gb|AAB51320.1| (U47924) neuron specific gamma-enolase [Homo sapiens] Length = 434 Score = 466 bits (1186), Expect = e-130 Identities = 251/431 (58%), Positives = 315/431 (72%), Gaps = 17/431 (3%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67 I + AREILDSRGNPTVEVD++T + RAAVPSGASTG +EA+ELRDG K RY GKGV Sbjct: 3 IEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGV 62 Query: 68 RRAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 +AV+++N IAP L+ G+ V Q ++D L++ELDGTENKS GANAIL VSLAV KA Sbjct: 63 LKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAG 122 Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182 A ELPLY++ L G + +LPVP NVINGG HAGN L QEFMI+P+GA SFR+A+ Sbjct: 123 AAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAM 182 Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242 R +E YH LK VI +KYGK+A NVGDEGGFAP + E +E L+++ +AI++AGY E+I Sbjct: 183 RLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYT--EKI 240 Query: 243 ALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEED 295 + +D A+SEFY+DGKY + K T ++L LY++ YP+VSIEDPF ++D Sbjct: 241 VIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDD 300 Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355 W + T +G +QIVGDDL VTNPKR+++ +E A N LLLKVNQIG++TEA+ A Sbjct: 301 WAAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACK 358 Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415 +A G+GV+VSHRSGETED IADL V L GQIKTGAP RS+R AKYNQL+RIEEEL Sbjct: 359 LAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELG 418 Query: 416 GVAVYAGKNFR 426 A +AG NFR Sbjct: 419 DEARFAGHNFR 429 >sp|P30575|ENO1_CANAL ENOLASE 1 (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|422073|pir||A40624 phosphopyruvate hydratase (EC 4.2.1.11) - yeast (Candida albicans) >gi|170861|gb|AAB46358.1| (L04943) enolase [Candida albicans] >gi|170863|gb|AAA71939.1| (L10290) enolase [Candida albicans] >gi|170865|gb|AAA34341.1| (M93712) enolase [Candida albicans] Length = 440 Score = 466 bits (1185), Expect = e-130 Identities = 251/430 (58%), Positives = 313/430 (72%), Gaps = 18/430 (4%) Query: 14 AREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRAVE 72 AR + DSRGNPTVEVD T + R+ VPSGASTG HEA+ELRDG K ++ GKGV +AV Sbjct: 9 ARYVYDSRGNPTVEVDFTTDKGLFRSIVPSGASTGVHEALELRDGDKSKWLGKGVLKAVA 68 Query: 73 NVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANALE 130 NVN IIAP L+ +DV Q +ID L+ LDGT NKS LGANAIL VSLA A AAA A Sbjct: 69 NVNDIIAPALIKAKIDVVDQAKIDEFLLSLDGTPNKSKLGANAILGVSLAAANAAAAAQG 128 Query: 131 LPLYQYLGGVN-----AYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWV 185 +PLY+++ ++ +VLPVP NV+NGG HAG L FQEFMI P G ++F EA+R Sbjct: 129 IPLYKHIANISNAKKGKFVLPVPFQNVLNGGSHAGGALAFQEFMIAPTGVSTFSEALRIG 188 Query: 186 SETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALA 245 SE YH LK + +KYG++A NVGDEGG AP +K E LD+++ AI++AGYK ++ +A Sbjct: 189 SEVYHNLKSLTKKKYGQSAGNVGDEGGVAPDIKTPKEALDLIMDAIDKAGYKG--KVGIA 246 Query: 246 LDAASSEFYKDGKYIVSGKEYTRE--------ELLELYKELTSTYPIVSIEDPFHEEDWE 297 +D ASSEFYKDGKY + K + +L +LY++L S YPIVSIEDPF E+DW+ Sbjct: 247 MDVASSEFYKDGKYDLDFKNPESDPSKWLSGPQLADLYEQLISEYPIVSIEDPFAEDDWD 306 Query: 298 GFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMA 357 +V +G K+QIVGDDL VTNP R+K IE AANALLLKVNQIGTLTE++ AA + Sbjct: 307 AWVHFFERVGDKIQIVGDDLTVTNPTRIKTAIEKKAANALLLKVNQIGTLTESIQAANDS 366 Query: 358 FRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGV 417 + AG+GV+VSHRSGETED IADL+V L +GQIKTGAPARS+R AK NQ++RIEEEL Sbjct: 367 YAAGWGVMVSHRSGETEDTFIADLSVGLRSGQIKTGAPARSERLAKLNQILRIEEELGSE 426 Query: 418 AVYAGKNFRK 427 A+YAGK+F+K Sbjct: 427 AIYAGKDFQK 436 >sp|Q27727|ENO_PLAFA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|542426|pir||S42206 phosphopyruvate hydratase (EC 4.2.1.11) - malaria parasite (Plasmodium falciparum) >gi|392027|gb|AAA18634.1| (U00152) enolase [Plasmodium falciparum] Length = 446 Score = 465 bits (1184), Expect = e-130 Identities = 249/440 (56%), Positives = 321/440 (72%), Gaps = 24/440 (5%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67 I + AREILDSRGNPTVEVD+ T + + RAAVPSGASTG +EA+ELRD K RY GKGV Sbjct: 5 ITRINAREILDSRGNPTVEVDLETNLGIFRAAVPSGASTGIYEALELRDNDKSRYLGKGV 64 Query: 68 RRAVENVNKIIAPELVGMDVRWQREIDRLLIE-LDGTEN-----KSNLGANAILAVSLAV 121 ++A++N+N+IIAP+L+GM+ Q++ID L++E LDG++N KS LGANAILA+S+AV Sbjct: 65 QKAIKNINEIIAPKLIGMNCTEQKKIDNLMVEELDGSKNEWGWSKSKLGANAILAISMAV 124 Query: 122 AKAAANALELPLYQYLGGV-----NAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGAN 176 +A A ++ LY+YL + + VLPVP NVINGG HAGN L FQEFMI+P+GA Sbjct: 125 CRAGAAPNKVSLYKYLAQLAGKKSDQMVLPVPCLNVINGGSHAGNKLSFQEFMIVPVGAP 184 Query: 177 SFREAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGY 236 SF+EA+R+ +E YH LK I +KYG +A NVGDEGGFAP + E LD+L+ AI+ AGY Sbjct: 185 SFKEALRYGAEVYHTLKSEIKKKYGIDATNVGDEGGFAPNILNANEALDLLVTAIKSAGY 244 Query: 237 KPGEEIALALDAASSEFYK--------DGKYIVSGKEY--TREELLELYKELTSTYPIVS 286 + ++ +A+D A+SEFY D K + K T +L++LY +L YPIVS Sbjct: 245 EG--KVKIAMDVAASEFYNSENKTYDLDFKTPNNDKSLVKTGAQLVDLYIDLVKKYPIVS 302 Query: 287 IEDPFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGT 346 IEDPF ++DWE + +T +GK VQIVGDDL VTNP R+ K +E A NALLLKVNQIG+ Sbjct: 303 IEDPFDQDDWENYAKLTAAIGKDVQIVGDDLLVTNPTRITKALEKNACNALLLKVNQIGS 362 Query: 347 LTEAMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQ 406 +TEA++A ++ + +GV+VSHRSGETED IADL VAL GQIKTGAP RS+RNAKYNQ Sbjct: 363 ITEAIEACLLSQKNNWGVMVSHRSGETEDVFIADLVVALRTGQIKTGAPCRSERNAKYNQ 422 Query: 407 LIRIEEELEGVAVYAGKNFR 426 L+RIEE L AV+AG+ FR Sbjct: 423 LLRIEESLGNNAVFAGEKFR 442 >emb|CAA31512.1| (X13120) neurone-specific enolase [Homo sapiens] >gi|930101|emb|CAA32505.1| (X14327) gamma enolase [Homo sapiens] Length = 433 Score = 465 bits (1183), Expect = e-130 Identities = 250/431 (58%), Positives = 315/431 (73%), Gaps = 17/431 (3%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67 I + AREILDSRGNPTVEVD++T + RAAVPSGASTG +EA+ELRDG K RY GKGV Sbjct: 2 IQKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGV 61 Query: 68 RRAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 +AV+++N IAP L+ G+ V Q ++D L++ELDGTENKS GANAIL VSLAV KA Sbjct: 62 LKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAG 121 Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182 A ELPLY++ L G + +LPVP NVINGG HAGN L QEFMI+P+GA SFR+A+ Sbjct: 122 AAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAM 181 Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242 R +E YH LK VI +KYGK+A NVGDEGGFAP + E +E L+++ +AI++AGY E++ Sbjct: 182 RLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYT--EKM 239 Query: 243 ALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEED 295 + +D A+SEFY+DGKY + K T ++L LY++ YP+VSIEDPF ++D Sbjct: 240 VIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDD 299 Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355 W + T +G +QIVGDDL VTNPKR+++ +E A N LLLKVNQIG++TEA+ A Sbjct: 300 WAAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACK 357 Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415 +A G+GV+VSHRSGETED IADL V L GQIKTGAP RS+R AKYNQL+RIEEEL Sbjct: 358 LAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELG 417 Query: 416 GVAVYAGKNFR 426 A +AG NFR Sbjct: 418 DEARFAGHNFR 428 >sp|P26300|ENO_LYCES ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|82082|pir||JQ1185 phosphopyruvate hydratase (EC 4.2.1.11) - tomato >gi|19281|emb|CAA41115.1| (X58108) enolase [Lycopersicon esculentum] Length = 444 Score = 465 bits (1183), Expect = e-130 Identities = 257/440 (58%), Positives = 317/440 (71%), Gaps = 25/440 (5%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMG---RAAVPSGASTGTHEAVELRDGGKRYHGK 65 I ++ AR+I DSRGNPTVEVDVH IS G RAAVPSGASTG +EA+ELRDGG Y GK Sbjct: 4 IKSIKARQIFDSRGNPTVEVDVH--ISNGVFARAAVPSGASTGIYEALELRDGGSDYLGK 61 Query: 66 GVRRAVENVNKIIAPELVGMDVRWQREIDRLLI-ELDGTEN-----KSNLGANAILAVSL 119 GV +AV NVN II P LVG D Q +D ++ +LDGT+N K LGANAILAVSL Sbjct: 62 GVSKAVNNVNSIIGPALVGKDPTDQTGLDNFMVHQLDGTQNEWGWCKEKLGANAILAVSL 121 Query: 120 AVAKAAANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGAN 176 AV KA A +PLY++ L G VLPVP NVINGG HAGN L QEFMI+P+GA Sbjct: 122 AVCKAGAAVRNVPLYKHIADLAGNKKLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGAA 181 Query: 177 SFREAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGY 236 +F+EA++ E YH LK VI +KYG++A NVGDEGGFAP ++E E L++L AIE+AGY Sbjct: 182 NFKEAMKMGCEVYHHLKAVIKKKYGQDATNVGDEGGFAPNIQENKEGLELLKTAIEKAGY 241 Query: 237 KPGEEIALALDAASSEFY-KDGKYIVSGKEYTRE--------ELLELYKELTSTYPIVSI 287 ++ + +D A+SEFY KD Y ++ KE + + +L +LYK S YPIVSI Sbjct: 242 TG--KVVIGMDVAASEFYGKDKSYDLNFKEESNDGSQKISGDQLKDLYKSFVSEYPIVSI 299 Query: 288 EDPFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTL 347 EDPF ++DWE + +T E+G++VQIVGDDL VTNPKR+ K I NALLLKVNQIG++ Sbjct: 300 EDPFDQDDWETYAKLTAEIGEQVQIVGDDLLVTNPKRVAKAIAEKTCNALLLKVNQIGSV 359 Query: 348 TEAMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQL 407 TE+++A M+ +AG+GV+ SHRSGETED IADLAV L+ GQIKTGAP RS+R AKYNQL Sbjct: 360 TESIEAVKMSKKAGWGVMTSHRSGETEDTFIADLAVGLSTGQIKTGAPCRSERLAKYNQL 419 Query: 408 IRIEEELEGVAVYAGKNFRK 427 +RIEEEL AVYAG +FRK Sbjct: 420 LRIEEELGSEAVYAGASFRK 439 >sp|P09104|ENOG_HUMAN GAMMA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (NEURAL ENOLASE) (NSE) Length = 434 Score = 465 bits (1183), Expect = e-130 Identities = 250/431 (58%), Positives = 315/431 (73%), Gaps = 17/431 (3%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67 I + AREILDSRGNPTVEVD++T + RAAVPSGASTG +EA+ELRDG K RY GKGV Sbjct: 3 IQKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGV 62 Query: 68 RRAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 +AV+++N IAP L+ G+ V Q ++D L++ELDGTENKS GANAIL VSLAV KA Sbjct: 63 LKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAG 122 Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182 A ELPLY++ L G + +LPVP NVINGG HAGN L QEFMI+P+GA SFR+A+ Sbjct: 123 AAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAM 182 Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242 R +E YH LK VI +KYGK+A NVGDEGGFAP + E +E L+++ +AI++AGY E++ Sbjct: 183 RLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYT--EKM 240 Query: 243 ALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEED 295 + +D A+SEFY+DGKY + K T ++L LY++ YP+VSIEDPF ++D Sbjct: 241 VIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDD 300 Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355 W + T +G +QIVGDDL VTNPKR+++ +E A N LLLKVNQIG++TEA+ A Sbjct: 301 WAAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACK 358 Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415 +A G+GV+VSHRSGETED IADL V L GQIKTGAP RS+R AKYNQL+RIEEEL Sbjct: 359 LAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELG 418 Query: 416 GVAVYAGKNFR 426 A +AG NFR Sbjct: 419 DEARFAGHNFR 429 >dbj|BAA76924.1| (AB026051) enolase [Plasmodium falciparum] Length = 446 Score = 464 bits (1182), Expect = e-130 Identities = 249/440 (56%), Positives = 321/440 (72%), Gaps = 24/440 (5%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67 I + AREILDSRGNPTVEVD+ T + + RAAVPSGASTG +EA+ELRD K RY GKGV Sbjct: 5 ITRINAREILDSRGNPTVEVDLETNLGIFRAAVPSGASTGIYEALELRDNDKSRYLGKGV 64 Query: 68 RRAVENVNKIIAPELVGMDVRWQREIDRLLIE-LDGTEN-----KSNLGANAILAVSLAV 121 ++A++N+N+IIAP+L+GM+ Q++ID L++E LDG++N KS LGANAILA+S+AV Sbjct: 65 QKAIKNINEIIAPKLIGMNCTEQKKIDNLMVEELDGSKNEWGWSKSKLGANAILAISMAV 124 Query: 122 AKAAANALELPLYQYLGGV-----NAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGAN 176 +A A A ++ LY+YL + + VLPVP NVINGG HAGN L FQEFMI+P+GA Sbjct: 125 CRAGAAANKVSLYKYLAQLAGKKSDQMVLPVPCLNVINGGSHAGNKLSFQEFMIVPVGAP 184 Query: 177 SFREAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGY 236 SF+EA+R+ +E YH LK I +KYG +A NVGDEGGFAP + E LD+L+ AI+ AGY Sbjct: 185 SFKEALRYGAEVYHTLKSEIKKKYGIDATNVGDEGGFAPNILNANEALDLLVTAIKSAGY 244 Query: 237 KPGEEIALALDAASSEFYK--------DGKYIVSGKEY--TREELLELYKELTSTYPIVS 286 + ++ +A+D A+SEFY D K + K T +L++LY +L YPIVS Sbjct: 245 EG--KVKIAMDVAASEFYNSENKTYDLDFKTPNNDKSLVKTGAQLVDLYIDLVKKYPIVS 302 Query: 287 IEDPFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGT 346 IEDPF ++DWE + +T +GK VQIVGDDL VTNP R+ K +E A NAL LKVNQIG+ Sbjct: 303 IEDPFDQDDWENYAKLTAAIGKDVQIVGDDLLVTNPTRITKALEKNACNALPLKVNQIGS 362 Query: 347 LTEAMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQ 406 +TEA++A ++ + +GV+VSHRSGETED IADL VAL GQIKTGAP RS+RNAKYNQ Sbjct: 363 ITEAIEACLLSQKNNWGVMVSHRSGETEDVFIADLVVALRTGQIKTGAPCRSERNAKYNQ 422 Query: 407 LIRIEEELEGVAVYAGKNFR 426 L+RIEE L AV+AG+ FR Sbjct: 423 LLRIEESLGNNAVFAGEKFR 442 >pir||JC1039 phosphopyruvate hydratase (EC 4.2.1.11) - rat Length = 434 Score = 464 bits (1181), Expect = e-130 Identities = 249/431 (57%), Positives = 314/431 (72%), Gaps = 17/431 (3%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67 I + AREILDSRGNPTVEVD+HT + RAAVPSGASTG +EA+ELRDG K RY GKGV Sbjct: 3 IQKIWAREILDSRGNPTVEVDLHTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGV 62 Query: 68 RRAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 +AV+++N IAP L+ G+ V Q ++D L++ELDGTENKS GANAIL VSLAV KA Sbjct: 63 LKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAG 122 Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182 A LPLY++ L G + +LPVP NVINGG HAGN L QEFMI+P+GA SFR+A+ Sbjct: 123 AAEKNLPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAM 182 Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242 R +E YH LK VI +KYGK+A NVGDEGGFAP + E +E L+++ +AI++AGY E++ Sbjct: 183 RLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYT--EKM 240 Query: 243 ALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEED 295 + +D A+SEFY+DGKY + K T ++L LY++ YP+VSIEDPF ++D Sbjct: 241 VIGMDVAASEFYRDGKYDLDFKSPADPSRCITGDQLGALYQDFVRNYPVVSIEDPFDQDD 300 Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355 W + T +G +QIVGDDL VTNPKR+++ +E A N LLLKVNQIG++TEA+ A Sbjct: 301 WAAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACK 358 Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415 +A G+GV+VSHRSGETED IADL V L GQIKTGAP RS+R AKYNQL+RIEEE+ Sbjct: 359 LAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEEVG 418 Query: 416 GVAVYAGKNFR 426 A +AG NFR Sbjct: 419 EEARFAGHNFR 429 >pir||A53665 phosphopyruvate hydratase (EC 4.2.1.11) - liver fluke Length = 431 Score = 464 bits (1180), Expect = e-129 Identities = 250/432 (57%), Positives = 311/432 (71%), Gaps = 17/432 (3%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGKRYHGKGVR 68 I A+ AR+I DSRGNPTVEVDV T + RAAVPSGASTG HEA+ELRDG Y GKGV Sbjct: 3 IKAIHARQIFDSRGNPTVEVDVTTAKGLFRAAVPSGASTGVHEALELRDGPPGYMGKGVL 62 Query: 69 RAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAA 126 +AV NVN IAP L+ G++V Q +D+ +++LDGT NK LGANAIL VSLAV KA A Sbjct: 63 KAVANVNSQIAPNLIKSGINVTDQAAVDKFMLDLDGTPNKEKLGANAILGVSLAVCKAGA 122 Query: 127 NALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIR 183 LPLY+Y L G ++PVP NVINGG HAGN L QEFMIMP GA+SF EA++ Sbjct: 123 AEKGLPLYKYIATLAGNKEVIMPVPSFNVINGGSHAGNKLAMQEFMIMPTGASSFTEAMK 182 Query: 184 WVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIA 243 SE YH L+ VI KYG +A NVGDEGGFAP +++ E L++L AI++AGY ++ Sbjct: 183 IGSEVYHNLRAVIKSKYGLDACNVGDEGGFAPSIQDNLEGLELLRTAIDKAGYTG--KVK 240 Query: 244 LALDAASSEFYKDGKYIVSGKE--------YTREELLELYKELTSTYPIVSIEDPFHEED 295 +A+D A+SEFYK+GKY + K T + + ++YK++ STYPIVSIEDPF ++D Sbjct: 241 IAMDCAASEFYKEGKYDLDFKNPKSQASSWITSDAMADVYKKMMSTYPIVSIEDPFDQDD 300 Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355 W + +T E K+QIVGDDL VTNP R++K I+ A N LLLKVNQIG+++E++ A Sbjct: 301 WPAWTKLTGEC--KIQIVGDDLTVTNPLRVQKAIDQKACNCLLLKVNQIGSVSESIKACK 358 Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415 MA AG+GV+VSHRSGETED IADL V L GQIKTGAP RS+R AKYNQL+RIEE+L Sbjct: 359 MAQEAGWGVMVSHRSGETEDNFIADLVVGLRTGQIKTGAPCRSERLAKYNQLLRIEEDLG 418 Query: 416 GVAVYAGKNFRK 427 G A YAG+NFR+ Sbjct: 419 GAAKYAGENFRR 430 >gi|7305027 enolase 2, gamma neuronal [Mus musculus] >gi|119348|sp|P17183|ENOG_MOUSE GAMMA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (NEURAL ENOLASE) (NSE) >gi|109805|pir||S10247 phosphopyruvate hydratase (EC 4.2.1.11) gamma - mouse >gi|55495|emb|CAA36606.1| (X52380) gamma-enolase (AA 1-434) [Mus sp.] >gi|2289903|gb|AAC36002.1| (AC002397) ENO2 [Mus musculus] Length = 434 Score = 463 bits (1178), Expect = e-129 Identities = 249/431 (57%), Positives = 315/431 (72%), Gaps = 17/431 (3%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67 I + AREILDSRGNPTVEVD++T + RAAVPSGASTG +EA+ELRDG K RY GKGV Sbjct: 3 IEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGV 62 Query: 68 RRAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 +AV+++N IAP L+ G+ V Q ++D L++ELDGTENKS GANAIL VSLAV KA Sbjct: 63 LKAVDHINSRIAPALISSGISVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAG 122 Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182 A +LPLY++ L G + +LPVP NVINGG HAGN L QEFMI+P+GA SFR+A+ Sbjct: 123 AAERDLPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAM 182 Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242 R +E YH LK VI +KYGK+A NVGDEGGFAP + E +E L+++ +AI++AGY E++ Sbjct: 183 RLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYT--EKM 240 Query: 243 ALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEED 295 + +D A+SEFY+DGKY + K T ++L LY++ YP+VSIEDPF ++D Sbjct: 241 VIGMDVAASEFYRDGKYDLDFKSPADPSRYITGDQLGALYQDFVRNYPVVSIEDPFDQDD 300 Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355 W + T +G +QIVGDDL VTNPKR+++ +E A N LLLKVNQIG++TEA+ A Sbjct: 301 WAAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACK 358 Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415 +A G+GV+VSHRSGETED IADL V L GQIKTGAP RS+R AKYNQL+RIEEEL Sbjct: 359 LAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELG 418 Query: 416 GVAVYAGKNFR 426 A +AG NFR Sbjct: 419 DEARFAGHNFR 429 >emb|CAC00532.1| (AJ132580) enolase, isoform 1 [Hevea brasiliensis] Length = 445 Score = 463 bits (1178), Expect = e-129 Identities = 257/438 (58%), Positives = 314/438 (71%), Gaps = 21/438 (4%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPIS-MGRAAVPSGASTGTHEAVELRDGGKRYHGKGV 67 IV+V AR+I DSRGNPTVE DV + RAAVPSGASTG +EA+ELRDGG Y GKGV Sbjct: 5 IVSVRARQIFDSRGNPTVEADVKLSDGYLARAAVPSGASTGIYEALELRDGGSDYLGKGV 64 Query: 68 RRAVENVNKIIAPELVGMDVRWQREIDRLLIE-LDGTEN-----KSNLGANAILAVSLAV 121 +AVENVN II P LVG D Q ID +++ LDGT N K LGANAILAVSLAV Sbjct: 65 SKAVENVNIIIGPALVGKDPTDQVGIDNFMVQQLDGTVNEWGWCKQKLGANAILAVSLAV 124 Query: 122 AKAAANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSF 178 KA A+ +PLY++ L G VLPVP NVINGG HAGN L QEFMI+P+GA+SF Sbjct: 125 CKAGAHVKGIPLYEHIANLAGNKNLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSF 184 Query: 179 REAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKP 238 +EA++ +E YH LK VI +KYG++A NVGDEGGFAP ++E E L++L AI +AGY Sbjct: 185 KEAMKMGAEVYHHLKSVIKKKYGQDATNVGDEGGFAPNIQENKEGLELLKTAIAKAGYTG 244 Query: 239 GEEIALALDAASSEFY-KDGKYIVSGKEYTR--------EELLELYKELTSTYPIVSIED 289 ++ + +D A+SEFY D Y ++ KE E L +LYK + YPIVSIED Sbjct: 245 --KVVIGMDVAASEFYGSDQTYDLNFKEENNNGSQKISGEALKDLYKSFVAEYPIVSIED 302 Query: 290 PFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTE 349 PF ++DW + +T E+G+KVQIVGDDL VTNPKR++K I+ A NALLLKVNQIG++TE Sbjct: 303 PFDQDDWAHYAKLTSEIGEKVQIVGDDLLVTNPKRVEKAIKEKACNALLLKVNQIGSVTE 362 Query: 350 AMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIR 409 +++A M+ RAG+GV+ SHRSGETED IADL+V L GQIKTGAP RS+R AKYNQL+R Sbjct: 363 SIEAVKMSKRAGWGVMASHRSGETEDTFIADLSVGLATGQIKTGAPCRSERLAKYNQLLR 422 Query: 410 IEEELEGVAVYAGKNFRK 427 IEEEL AVYAG NFRK Sbjct: 423 IEEELGSEAVYAGANFRK 440 >sp|P42896|ENO_RICCO ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|542019|pir||S39203 phosphopyruvate hydratase (EC 4.2.1.11) - castor bean >gi|433609|emb|CAA82232.1| (Z28386) enolase [Ricinus communis] Length = 445 Score = 462 bits (1177), Expect = e-129 Identities = 254/437 (58%), Positives = 313/437 (71%), Gaps = 21/437 (4%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPIS-MGRAAVPSGASTGTHEAVELRDGGKRYHGKGV 67 IV+V AR+I DSRGNPTVE D+ + RAAVPSGASTG +EA+ELRDGG Y GKGV Sbjct: 5 IVSVRARQIFDSRGNPTVEADIKLSDGHLARAAVPSGASTGIYEALELRDGGSDYLGKGV 64 Query: 68 RRAVENVNKIIAPELVGMDVRWQREIDRLLI-ELDGTEN-----KSNLGANAILAVSLAV 121 +AVENVN II P L+G D Q +D ++ ELDGT N K LGANAILAVSLA+ Sbjct: 65 SKAVENVNSIIGPALIGKDPTEQTALDNFMVQELDGTVNEWGWCKQKLGANAILAVSLAL 124 Query: 122 AKAAANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSF 178 KA A+ +PLY++ L G VLPVP NVINGG HAGN L QEFMI+P+GA+SF Sbjct: 125 CKAGAHVKGIPLYKHIANLAGNKNLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSF 184 Query: 179 REAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKP 238 +EA++ +E YH LK VI +KYG++A NVGDEGGFAP ++E E L++L AI +AGY Sbjct: 185 KEAMKMGAEVYHHLKSVIKKKYGQDATNVGDEGGFAPNIQENKEGLELLKTAIAKAGYTG 244 Query: 239 GEEIALALDAASSEFY-KDGKYIVSGKEYTR--------EELLELYKELTSTYPIVSIED 289 ++ + +D A+SEFY D Y ++ KE E L +LYK S YPIVSIED Sbjct: 245 --KVVIGMDVAASEFYGSDKTYDLNFKEENNDGSQKISGEALKDLYKSFASEYPIVSIED 302 Query: 290 PFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTE 349 PF ++DWE + +T E+G+KVQIVGDDL VTNPKR++K I+ A NALLLKVNQIG++TE Sbjct: 303 PFDQDDWEHYSKLTSEIGEKVQIVGDDLLVTNPKRVEKAIQEKACNALLLKVNQIGSVTE 362 Query: 350 AMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIR 409 +++A M+ RAG+GV+ SHRSGETED IADL+V L GQIKTGAP RS+R AKYNQL+R Sbjct: 363 SIEAVRMSKRAGWGVMASHRSGETEDTFIADLSVGLATGQIKTGAPCRSERLAKYNQLLR 422 Query: 410 IEEELEGVAVYAGKNFR 426 IEEEL AVYAG FR Sbjct: 423 IEEELGAEAVYAGAKFR 439 >sp|O57391|ENOG_CHICK GAMMA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (NEURAL ENOLASE) (NSE) >gi|2842531|dbj|BAA24680.1| (AB004291) gamma-subunit of enolase [Gallus gallus] Length = 434 Score = 462 bits (1177), Expect = e-129 Identities = 248/426 (58%), Positives = 314/426 (73%), Gaps = 17/426 (3%) Query: 14 AREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRAVE 72 AREILDSRGNPTVEVD++T M RAAVPSGASTG +EA+ELRD K R+ GKGV +AV+ Sbjct: 8 AREILDSRGNPTVEVDLYTHKGMFRAAVPSGASTGIYEALELRDNDKSRFLGKGVLQAVD 67 Query: 73 NVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANALE 130 ++N +AP +VG + V Q +ID L++E+DGTENKS GANAIL VSLAV KA A + Sbjct: 68 HINSTVAPAIVGSGLSVVDQEKIDNLMLEMDGTENKSKFGANAILGVSLAVCKAGAAEKD 127 Query: 131 LPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVSE 187 +PLY++ L G + +LPVP NVINGG HAGN L QEFMI+P+GA SFR+A+R +E Sbjct: 128 VPLYRHIADLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMRIGAE 187 Query: 188 TYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALALD 247 YH LK VI EKYGK+A NVGDEGGFAP + E +E L++L +AI++AGY ++I + +D Sbjct: 188 VYHNLKSVIKEKYGKDATNVGDEGGFAPNILENSEALELLKEAIDKAGYT--DKIVIGMD 245 Query: 248 AASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEEDWEGFV 300 A+SEFY+DGKY + K + +EL +LY+ YP++SIEDPF ++DWE + Sbjct: 246 VAASEFYRDGKYDLDFKSPDDPSRYISADELGDLYQSFVRAYPVLSIEDPFDQDDWEAWS 305 Query: 301 MITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRA 360 T +G +QIVGDDL VTNPKR+++ +E A N LLLKVNQIG++TEA+ A +A Sbjct: 306 KFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQEN 363 Query: 361 GYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVY 420 G+GV+VSHRSGETED IADL VAL GQIKTGAP RS+R AKYNQL+RIEEEL A + Sbjct: 364 GWGVMVSHRSGETEDTFIADLVVALCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARF 423 Query: 421 AGKNFR 426 AG NFR Sbjct: 424 AGHNFR 429 >sp|O85348|ENO_NITEU ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|3493583|gb|AAC33442.1| (AF061753) enolase; 2-phospho-D-glycerate hydrolase [Nitrosomonas europaea] Length = 428 Score = 462 bits (1177), Expect = e-129 Identities = 243/420 (57%), Positives = 312/420 (73%), Gaps = 6/420 (1%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPIS-MGRAAVPSGASTGTHEAVELRDG-GKRYHGKG 66 IV VIAREI+DSRGNPT+E DV +GRA+VPSGAS GT EAVELRDG +RY+GKG Sbjct: 4 IVDVIAREIIDSRGNPTIEADVLLESGVLGRASVPSGASVGTREAVELRDGDAQRYYGKG 63 Query: 67 VRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAA 126 V +AVE+VN I+ ++G+D Q ID+ LIELDG+ENKS LGANAILAVSLAVAKAAA Sbjct: 64 VLKAVESVNGEISETIMGLDAMEQCFIDKTLIELDGSENKSRLGANAILAVSLAVAKAAA 123 Query: 127 NALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVS 186 LPLY+YLGG+NA LPVP+ N++NGGVHA N LD QEFMI+P+G + REA+R + Sbjct: 124 EESGLPLYRYLGGINAKWLPVPMMNLVNGGVHANNRLDMQEFMIIPLGLPNLREAVRCGA 183 Query: 187 ETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALAL 246 E + L+ ++ ++ VGDEGGFAP E L ++++AI+EAGY+PG E+A+ + Sbjct: 184 EVFSTLRTLLNKR--NLPTTVGDEGGFAPSFARNEEALALIVQAIDEAGYQPGSEVAIGV 241 Query: 247 DAASSEFYKDGKYI--VSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMITR 304 D ASSEF+++GKY V G T + ++ YPI+SIED E+DWEG+ ++T Sbjct: 242 DCASSEFFREGKYHLDVDGLGLTSAQFVDYLATWVEKYPIISIEDGMSEQDWEGWGLLTE 301 Query: 305 ELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYGV 364 LGK VQ+VGDD+FVTN + LK+GI AN++L+K+NQIGTLTE ++A MA AGY Sbjct: 302 RLGKTVQLVGDDVFVTNTRILKEGISRNIANSILIKINQIGTLTETLNAIEMAKCAGYTA 361 Query: 365 VVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAGKN 424 +VSHRSGETED TIAD+AVA NA QIKTG+ +RSDR AKYNQL+RIEE+L +A YAG++ Sbjct: 362 IVSHRSGETEDTTIADIAVATNALQIKTGSLSRSDRLAKYNQLLRIEEDLGEMAQYAGRS 421 >sp|Q27655|ENO_FASHE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|499267|gb|AAA57450.1| (U10297) enolase [Fasciola hepatica] Length = 431 Score = 462 bits (1176), Expect = e-129 Identities = 249/432 (57%), Positives = 310/432 (71%), Gaps = 17/432 (3%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGKRYHGKGVR 68 I A+ AR+I DSRGNPTVEVDV T + RAAVPSGASTG HEA+ELRDG Y GKGV Sbjct: 3 IKAIHARQIFDSRGNPTVEVDVTTAKGLFRAAVPSGASTGVHEALELRDGPPGYMGKGVL 62 Query: 69 RAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAA 126 +AV NVN IAP L+ G++V Q +D+ +++LDGT NK LGANAIL VSLA KA A Sbjct: 63 KAVANVNSQIAPNLIKSGINVTDQAAVDKFMLDLDGTPNKEKLGANAILGVSLAXCKAGA 122 Query: 127 NALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIR 183 LPLY+Y L G ++PVP NVINGG HAGN L QEFMIMP GA+SF EA++ Sbjct: 123 AEKGLPLYKYIATLAGNKEVIMPVPSFNVINGGSHAGNKLAMQEFMIMPTGASSFTEAMK 182 Query: 184 WVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIA 243 SE YH L+ VI KYG +A NVGDEGGFAP +++ E L++L AI++AGY ++ Sbjct: 183 IGSEVYHNLRAVIKSKYGLDACNVGDEGGFAPSIQDNLEGLELLRTAIDKAGYTG--KVX 240 Query: 244 LALDAASSEFYKDGKYIVSGKE--------YTREELLELYKELTSTYPIVSIEDPFHEED 295 +A+D A+SEFYK+GKY + K T + + ++YK++ STYPIVSIEDPF ++D Sbjct: 241 IAMDCAASEFYKEGKYDLDFKNPKSQASSWITSDAMADVYKKMMSTYPIVSIEDPFDQDD 300 Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355 W + +T E K+QIVGDDL VTNP R++K I+ A N LLLKVNQIG+++E++ A Sbjct: 301 WPAWTKLTGEC--KIQIVGDDLTVTNPLRVQKAIDQKACNCLLLKVNQIGSVSESIKACK 358 Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415 MA AG+GV+VSHRSGETED IADL V L GQIKTGAP RS+R AKYNQL+RIEE+L Sbjct: 359 MAQEAGWGVMVSHRSGETEDNFIADLVVGLRTGQIKTGAPCRSERLAKYNQLLRIEEDLG 418 Query: 416 GVAVYAGKNFRK 427 G A YAG+NFR+ Sbjct: 419 GAAKYAGENFRR 430 >pir||A72477 probable enolase APE2458 - Aeropyrum pernix (strain K1) >gi|5106162|dbj|BAA81473.1| (AP000064) 432aa long hypothetical enolase [Aeropyrum pernix] Length = 432 Score = 462 bits (1175), Expect = e-129 Identities = 241/425 (56%), Positives = 297/425 (69%), Gaps = 1/425 (0%) Query: 5 NPYEIVAVIAREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRDGGKRYH 63 N + I V ++LDSRGNPTV+ V S+G PSGAS G EAVELRDGG ++ Sbjct: 4 NDFAIERVWGLQVLDSRGNPTVKAYVKLAGGSLGWGIAPSGASRGEREAVELRDGGGKWR 63 Query: 64 GKGVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAK 123 GKGV RAV +N ++AP L G+D R Q +IDRLLIELDGT NKS LG N A+S+AV++ Sbjct: 64 GKGVSRAVSLLNTVVAPRLEGVDARRQAQIDRLLIELDGTPNKSRLGGNTTTALSIAVSR 123 Query: 124 AAANALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIR 183 AAA L L+QYLGG A LP+PL NVINGGVHAGN+LDFQEFMI+P G SF EA+R Sbjct: 124 AAAAQARLELFQYLGGAGARRLPIPLLNVINGGVHAGNELDFQEFMIIPYGFESFTEAMR 183 Query: 184 WVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIA 243 ETY LK ++ ++YG +AVNVGDEGGFAPPM+ E L L+ A+E+AGY+PG EIA Sbjct: 184 AAVETYGELKSLLKDRYGASAVNVGDEGGFAPPMRSAEEALKTLVDAVEKAGYQPGSEIA 243 Query: 244 LALDAASSEFYKDGKYIVSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMIT 303 L +DAA+S+ Y +G+Y V GK +REELL LY+ L YPIV +EDPF E+D+EGF Sbjct: 244 LGIDAAASQLYSNGRYSVEGKSLSREELLSLYQRLVEQYPIVYLEDPFSEDDYEGFKAAV 303 Query: 304 RELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYG 363 L + IVGDDL VTNP+R+K+ + A LL+KVNQ+GTLTEA++A A G Sbjct: 304 DALSTETIIVGDDLLVTNPQRVKEASALKAVTGLLVKVNQVGTLTEALEAIQAARDRGIV 363 Query: 364 VVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAGK 423 +VSHRSG+TED IADLAVA A IKTGAPAR +R +KYN+L+ IE L A YAG Sbjct: 364 HIVSHRSGDTEDTFIADLAVATEALMIKTGAPARGERTSKYNRLLEIENILGYSAEYAGP 423 Query: 424 NFRKV 428 R V Sbjct: 424 ELRGV 428 >sp|P25696|ENO_ARATH ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|81608|pir||JQ1187 phosphopyruvate hydratase (EC 4.2.1.11) - Arabidopsis thaliana >gi|16271|emb|CAA41114.1| (X58107) enolase [Arabidopsis thaliana] >gi|4581151|gb|AAD24635.1|AC006919_15 (AC006919) enolase (2-phospho-D-glycerate hydroylase) [Arabidopsis thaliana] Length = 444 Score = 461 bits (1173), Expect = e-129 Identities = 254/438 (57%), Positives = 311/438 (70%), Gaps = 21/438 (4%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMG-RAAVPSGASTGTHEAVELRDGGKRYHGKGV 67 I V AR+I DSRGNPTVEVD+HT + AAVPSGASTG +EA+ELRDGG Y GKGV Sbjct: 4 ITVVKARQIFDSRGNPTVEVDIHTSNGIKVTAAVPSGASTGIYEALELRDGGSDYLGKGV 63 Query: 68 RRAVENVNKIIAPELVGMDVRWQREIDRLLI-ELDGTEN-----KSNLGANAILAVSLAV 121 +AV NVN II P L+G D Q ID ++ ELDGT+N K LGANAILAVSLAV Sbjct: 64 SKAVGNVNNIIGPALIGKDPTQQTAIDNFMVHELDGTQNEWGWCKQKLGANAILAVSLAV 123 Query: 122 AKAAANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSF 178 KA A +PLY++ L G VLPVP NVINGG HAGN L QEFMI+P+GA SF Sbjct: 124 CKAGAVVSGIPLYKHIANLAGNPKIVLPVPAFNVINGGSHAGNKLAMQEFMILPVGAASF 183 Query: 179 REAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKP 238 +EA++ E YH LK VI +KYG++A NVGDEGGFAP ++E E L++L AIE+AGY Sbjct: 184 KEAMKMGVEVYHHLKSVIKKKYGQDATNVGDEGGFAPNIQENKEGLELLKTAIEKAGYTG 243 Query: 239 GEEIALALDAASSEFYKDGK-YIVSGKEYTR--------EELLELYKELTSTYPIVSIED 289 ++ + +D A+SEFY + K Y ++ KE + L +LYK + YPIVSIED Sbjct: 244 --KVVIGMDVAASEFYSEDKTYDLNFKEENNNGSQKISGDALKDLYKSFVAEYPIVSIED 301 Query: 290 PFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTE 349 PF ++DWE + +T E G +VQIVGDDL VTNPKR+ K I + NALLLKVNQIG++TE Sbjct: 302 PFDQDDWEHYAKMTTECGTEVQIVGDDLLVTNPKRVAKAIAEKSCNALLLKVNQIGSVTE 361 Query: 350 AMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIR 409 +++A M+ +AG+GV+ SHRSGETED IADLAV L+ GQIKTGAP RS+R AKYNQL+R Sbjct: 362 SIEAVKMSKKAGWGVMTSHRSGETEDTFIADLAVGLSTGQIKTGAPCRSERLAKYNQLLR 421 Query: 410 IEEELEGVAVYAGKNFRK 427 IEEEL A+YAG NFRK Sbjct: 422 IEEELGSEAIYAGVNFRK 439 >sp|Q42971|ENO_ORYSA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (OSE1) >gi|7436887|pir||T03267 probable phosphopyruvate hydratase (EC 4.2.1.11) - rice >gi|780372|gb|AAC49173.1| (U09450) enolase [Oryza sativa] Length = 446 Score = 460 bits (1172), Expect = e-128 Identities = 253/438 (57%), Positives = 314/438 (70%), Gaps = 22/438 (5%) Query: 9 IVAVIAREILDSRGNPTVEVDVH-TPISMGRAAVPSGASTGTHEAVELRDGGKRYHGKGV 67 IV+V AR+I DSRGNPTVEVDV + + RAAVPSGASTG +EA+ELRDGG Y GKGV Sbjct: 5 IVSVKARQIFDSRGNPTVEVDVCCSDGTFARAAVPSGASTGVYEALELRDGGSDYLGKGV 64 Query: 68 RRAVENVNKIIAPELVGMDVRWQREIDRLLIE-LDGTEN-----KSNLGANAILAVSLAV 121 +AV+NVN +IAP L+G D Q E+D +++ LDGT+N K LGANAILAVSLA+ Sbjct: 65 SKAVDNVNSVIAPALIGKDPTSQAELDNFMVQQLDGTKNEWGWCKQKLGANAILAVSLAI 124 Query: 122 AKAAANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSF 178 KA A ++PLYQ+ L G VLPVP NVINGG HAGN L QEFMI+P GA SF Sbjct: 125 CKAGAIIKKIPLYQHIANLAGNKQLVLPVPAFNVINGGSHAGNKLAMQEFMILPTGAASF 184 Query: 179 REAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKP 238 +EA++ E YH LK VI +KYG++A NVGDEGGFAP ++E E L++L AIE+AGY Sbjct: 185 KEAMKMGVEVYHNLKSVIKKKYGQDATNVGDEGGFAPNIQENKEGLELLKTAIEKAGYTG 244 Query: 239 GEEIALALDAASSEFY--KDGKYIVSGKEYTRE--------ELLELYKELTSTYPIVSIE 288 ++ + +D A+SEFY KD Y ++ KE + L +YK S YPIVSIE Sbjct: 245 --KVVIGMDVAASEFYNDKDKTYDLNFKEENNDGSQKISGDSLKNVYKSFVSEYPIVSIE 302 Query: 289 DPFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLT 348 DPF ++DWE + +T E+G++VQIVGDDL VTNP R+ K I+ + NALLLKVNQIG++T Sbjct: 303 DPFDQDDWEHYAKMTAEIGEQVQIVGDDLLVTNPTRVAKAIQEKSCNALLLKVNQIGSVT 362 Query: 349 EAMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLI 408 E+++A M+ RAG+GV+ SHRSGETED IA+LAV L GQIKTGAP RS+R AKYNQL+ Sbjct: 363 ESIEAVKMSKRAGWGVMTSHRSGETEDTFIAELAVGLATGQIKTGAPCRSERLAKYNQLL 422 Query: 409 RIEEELEGVAVYAGKNFR 426 RIEEEL AVYAG FR Sbjct: 423 RIEEELGAAAVYAGAKFR 440 >gb|AAD41646.1|AF072589_1 (AF072589) alpha enolase [Python regius] Length = 434 Score = 460 bits (1172), Expect = e-128 Identities = 248/431 (57%), Positives = 310/431 (71%), Gaps = 17/431 (3%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67 I+ + AREI DSRGNPT+EVD++T + RAAVPSGASTG +EA+ELRD K R+ GKGV Sbjct: 3 ILKIQAREIFDSRGNPTIEVDLYTKKGLFRAAVPSGASTGIYEALELRDNDKTRFLGKGV 62 Query: 68 RRAVENVNKIIAPELVGMDVRW--QREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 +AVE+VNK IAP LV +V Q +ID+L+IE+DG+ENKS GANAIL VSLAV KA Sbjct: 63 SKAVEHVNKTIAPALVNKNVSVVEQEKIDKLMIEMDGSENKSKFGANAILGVSLAVCKAG 122 Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182 A ++PLY++ L G +LPVP NVINGG HAGN L QEFMI+PIGA F+EA+ Sbjct: 123 AAEKDIPLYRHIADLAGNKEVILPVPAFNVINGGSHAGNKLAMQEFMILPIGAECFKEAM 182 Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242 R +E YH LK VI EKYGK+A NVGDEGGFAP + E E L++L AI +AGY ++I Sbjct: 183 RIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKTAISKAGY--ADKI 240 Query: 243 ALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEED 295 + +D A+SEFY+DGKY + K T ++L +LYK YP+VSIEDPF ++D Sbjct: 241 VIGMDVAASEFYRDGKYDLDFKSPDDRSRYITPDQLADLYKGFVKNYPVVSIEDPFDQDD 300 Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355 W + T E G +Q+VGDDL VTNPKR+ K ++ + N LLLKVNQIG++TE++ A Sbjct: 301 WPAWKKFTAESG--IQVVGDDLTVTNPKRIAKAVQEKSCNCLLLKVNQIGSVTESLQACK 358 Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415 +A G+GV+VSHRSGETED IADL V L GQIKTGAP RS+R AKYNQL+RIEEEL Sbjct: 359 LAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELG 418 Query: 416 GVAVYAGKNFR 426 A +AG+NFR Sbjct: 419 SKARFAGRNFR 429 >sp|P42895|ENO2_MAIZE ENOLASE 2 (2-PHOSPHOGLYCERATE DEHYDRATASE 2) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE 2) >gi|7436888|pir||T02221 phosphopyruvate hydratase (EC 4.2.1.11) - maize >gi|602253|gb|AAD04187.1| (U17973) enolase [Zea mays] Length = 446 Score = 460 bits (1171), Expect = e-128 Identities = 253/438 (57%), Positives = 312/438 (70%), Gaps = 22/438 (5%) Query: 9 IVAVIAREILDSRGNPTVEVDVH-TPISMGRAAVPSGASTGTHEAVELRDGGKRYHGKGV 67 I +V AR+I DSRGNPTVEVDV + + RAAVPSGASTG +EA+ELRDGG Y GKGV Sbjct: 5 IQSVKARQIFDSRGNPTVEVDVFCSDGTFARAAVPSGASTGVYEALELRDGGSYYLGKGV 64 Query: 68 RRAVENVNKIIAPELVGMDVRWQREIDRLLIE-LDGTEN-----KSNLGANAILAVSLAV 121 +AV NVN +I P L+G D Q EID +++ LDGT+N K LGANAILAVSLAV Sbjct: 65 SKAVNNVNSVIGPALIGKDPTAQTEIDNFMVQQLDGTKNEWGWCKQKLGANAILAVSLAV 124 Query: 122 AKAAANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSF 178 KA A+ +PLYQ+ L G VLPVP NVINGG HAGN L QEFMI+P GA SF Sbjct: 125 CKAGASIKRIPLYQHIANLAGNKQLVLPVPAFNVINGGSHAGNKLAMQEFMILPTGAASF 184 Query: 179 REAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKP 238 +EA++ E YH LK VI +KYG++A NVGDEGGFAP ++E E L++L AIE+AGY Sbjct: 185 KEAMKMGVEVYHHLKSVIKKKYGQDATNVGDEGGFAPNIQENKEGLELLKTAIEKAGYTG 244 Query: 239 GEEIALALDAASSEFY--KDGKYIVSGKEYTRE--------ELLELYKELTSTYPIVSIE 288 ++ + +D A+SEFY KD Y ++ KE + L +YK S YPIVSIE Sbjct: 245 --KVVIGMDVAASEFYSDKDQTYDLNFKEENNDGSQKISGDSLKNVYKSFVSEYPIVSIE 302 Query: 289 DPFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLT 348 DPF ++DW + +T E+G++VQIVGDDL VTNP R+ K I+ + NALLLKVNQIG++T Sbjct: 303 DPFDQDDWVHYAKMTEEIGEQVQIVGDDLLVTNPTRVAKAIKEKSCNALLLKVNQIGSVT 362 Query: 349 EAMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLI 408 E+++A M+ RAG+GV+ SHRSGETED IADLAV L+ GQIKTGAP RS+R AKYNQL+ Sbjct: 363 ESIEAVKMSKRAGWGVMTSHRSGETEDTFIADLAVGLSTGQIKTGAPCRSERLAKYNQLL 422 Query: 409 RIEEELEGVAVYAGKNFR 426 RIEEEL +AVYAG FR Sbjct: 423 RIEEELGAIAVYAGAKFR 440 >sp|P08324|ENO_ECOLI ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|7428364|pir||NOEC phosphopyruvate hydratase (EC 4.2.1.11) - Escherichia coli (strain K-12) >gi|882673|gb|AAA69289.1| (U29580) enolase [Escherichia coli] >gi|1789141|gb|AAC75821.1| (AE000361) enolase [Escherichia coli K12] Length = 432 Score = 460 bits (1171), Expect = e-128 Identities = 249/425 (58%), Positives = 309/425 (72%), Gaps = 11/425 (2%) Query: 8 EIVAVIAREILDSRGNPTVEVDVHTPIS-MGRAAVPSGASTGTHEAVELRDGGK-RYHGK 65 +IV +I REI+DSRGNPTVE +VH +G AA PSGASTG+ EA+ELRDG K R+ GK Sbjct: 3 KIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGK 62 Query: 66 GVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 GV +AV VN IA L+G D + Q ID+++I+LDGTENKS GANAILAVSLA AKAA Sbjct: 63 GVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAA 122 Query: 126 ANALELPLYQYLGGVNA----YVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREA 181 A A +PLY+++ +N Y +PVP+ N+INGG HA N++D QEFMI P+GA + +EA Sbjct: 123 AAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEA 182 Query: 182 IRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEE 241 IR SE +H L KV+ K G N VGDEGG+AP + E L V+ +A++ AGY+ G++ Sbjct: 183 IRMGSEVFHHLAKVLKAK-GMNTA-VGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKD 240 Query: 242 IALALDAASSEFYKDGKYIVSG---KEYTREELLELYKELTSTYPIVSIEDPFHEEDWEG 298 I LA+D A+SEFYKDGKY+++G K +T EE +ELT YPIVSIED E DW+G Sbjct: 241 ITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDG 300 Query: 299 FVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAF 358 F T+ LG K+Q+VGDDLFVTN K LK+GIE G AN++L+K NQIG+LTE + A MA Sbjct: 301 FAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAK 360 Query: 359 RAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVA 418 AGY V+SHRSGETEDATIADLAV AGQIKTG+ +RSDR AKYNQLIRIEE L A Sbjct: 361 DAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKA 420 Query: 419 VYAGK 423 Y G+ Sbjct: 421 PYNGR 425 >sp|P33675|ENO_ZYMMO ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|538726|pir||A45732 phosphopyruvate hydratase (EC 4.2.1.11) - Zymomonas mobilis >gi|155581|gb|AAA27686.1| (M99380) enolase [Zymomonas mobilis] Length = 428 Score = 459 bits (1169), Expect = e-128 Identities = 248/422 (58%), Positives = 310/422 (72%), Gaps = 9/422 (2%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRDGGK-RYHGKG 66 IV++ R+++DSRGNPTVEVDV S GRAAVPSGASTG HEAVELRDG K R+ GKG Sbjct: 4 IVSIHGRQVVDSRGNPTVEVDVTLEDGSFGRAAVPSGASTGVHEAVELRDGDKTRWGGKG 63 Query: 67 VRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAA 126 V +AV VN IA ++G++ Q ID+ +I+LDGT NK GANAIL VSLAVAKAAA Sbjct: 64 VTKAVHAVNNEIANAIIGLEAEDQELIDQTMIKLDGTPNKGKFGANAILGVSLAVAKAAA 123 Query: 127 NALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVS 186 A LPLY+Y+GG A+VLPVP+ N++NGG+HA N +DFQEFMI P+GA+S EA+R + Sbjct: 124 EARGLPLYRYVGGTAAHVLPVPMMNIVNGGMHADNPIDFQEFMIAPVGASSINEAVRIGT 183 Query: 187 ETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALAL 246 E +H LKK ++ K G N NVGDEGGFAP + + LD ++ +I +AGYKPGE++ +AL Sbjct: 184 EVFHTLKKELSAK-GMN-TNVGDEGGFAPSLDSASSALDFIVDSISKAGYKPGEDVFIAL 241 Query: 247 DAASSEFYKDGKYIV----SGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMI 302 DAASSEFY + I G++ T +L++ Y EL YPI SIED E+D+E + ++ Sbjct: 242 DAASSEFYNKDQNIYDLKGEGRKLTSAQLVDYYVELCGKYPIYSIED-LAEDDFEFWKIL 300 Query: 303 TRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGY 362 T +LG KVQ+VGDDLFVTN KRL GIE G AN+LL+K NQIG+L+E + A MA A Y Sbjct: 301 TEKLGDKVQLVGDDLFVTNVKRLSDGIERGIANSLLVKFNQIGSLSETLAAVNMANDASY 360 Query: 363 GVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAG 422 V+SHRS ETED TIADLAVA N GQIKTG+ RS+R AKYNQL+RIEEEL VA YAG Sbjct: 361 TPVMSHRSVETEDTTIADLAVATNCGQIKTGSLCRSERIAKYNQLMRIEEELGSVAKYAG 420 Query: 423 KN 424 ++ Sbjct: 421 RS 422 >dbj|BAA81815.1| (AB029313) enolase [Streptococcus intermedius] Length = 434 Score = 459 bits (1169), Expect = e-128 Identities = 240/424 (56%), Positives = 303/424 (70%), Gaps = 12/424 (2%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRDGGK-RYHGKG 66 I V ARE+LDSRGNPT+EV+V+T + GR VPSGASTG HEAVELRDG K RY G G Sbjct: 4 ITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKSRYGGLG 63 Query: 67 VRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAA 126 ++AV+NVN IIA ++G DVR Q+ IDR +I LDGT NK LGANAIL VS+AVA+AAA Sbjct: 64 TQKAVDNVNNIIAEAVIGYDVRDQQAIDRAMIALDGTPNKGKLGANAILGVSIAVARAAA 123 Query: 127 NALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVS 186 + LE+PLY YLGG N VLP P+ N+INGG H+ + FQEFMI+P GA +F+EA+RW + Sbjct: 124 DYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPIAFQEFMIVPAGAPTFKEALRWGA 183 Query: 187 ETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALAL 246 E +H LKK++ + A VGDEGGFAP + ++ ++ AIE AGY PG+++ L Sbjct: 184 EIFHALKKILKSR--GLATAVGDEGGFAPRFDGTEDGVETILAAIEAAGYVPGKDVFLGF 241 Query: 247 DAASSEFYKDGKYIVSGKEY--------TREELLELYKELTSTYPIVSIEDPFHEEDWEG 298 D ASSEFY + + ++ T +E ++ +EL + YPI++IED E DW+G Sbjct: 242 DCASSEFYDKERKVYDYTKFEGEGAAVRTADEQIDYLEELVNKYPIITIEDGMDENDWDG 301 Query: 299 FVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAF 358 + +T LGKKVQ VGDD FVTN L+KGI AN++L+KVNQIGTLTE DA MA Sbjct: 302 WKKLTERLGKKVQPVGDDFFVTNTSYLEKGINEACANSILIKVNQIGTLTETFDAIEMAK 361 Query: 359 RAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVA 418 AGY VVSHRSGETED+TIAD+AVA NAGQIKTG+ +R+DR AKYNQL+RIE++L VA Sbjct: 362 EAGYTAVVSHRSGETEDSTIADIAVAANAGQIKTGSLSRTDRIAKYNQLLRIEDQLGEVA 421 Query: 419 VYAG 422 Y G Sbjct: 422 EYRG 425 >sp|Q43321|ENO_ALNGL ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|1041245|emb|CAA63121.1| (X92377) enolase [Alnus glutinosa] Length = 440 Score = 458 bits (1167), Expect = e-128 Identities = 253/438 (57%), Positives = 315/438 (71%), Gaps = 25/438 (5%) Query: 8 EIVAVIAREILDSRGNPTVEVDVHTPISM-GRAAVPSGASTGTHEAVELRDGGKRYHGKG 66 EI + AR+I DSRGNPTVE +V T + RAAVPSGASTG +EA+ELRDGG Y GKG Sbjct: 3 EITHIKARQIFDSRGNPTVEAEVTTANGVVSRAAVPSGASTGVYEALELRDGGSDYLGKG 62 Query: 67 VRRAVENVNKIIAPELVGMDVRWQR--EIDRLLIELDGTEN-----KSNLGANAILAVSL 119 V +AV+NVNKII P L+G D Q +ID + +LDGT N K LGANAILAVSL Sbjct: 63 VLKAVDNVNKIIGPALIGKDATEQTAIDIDFMFQQLDGTVNEWGWCKQKLGANAILAVSL 122 Query: 120 AVAKAAANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGAN 176 AV KA A+ ++PLY++ L G VLPVP NVINGG HAGN L QEFMI+P+GA+ Sbjct: 123 AVCKAGASVKKIPLYKHIANLAGNPKLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGAS 182 Query: 177 SFREAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGY 236 SF+EA++ E YH LK VI +KYG++A NVGDEGGFAP ++E E L++L AI +AGY Sbjct: 183 SFKEAMKMGVEVYHHLKAVIKKKYGQDATNVGDEGGFAPNIQENKEGLELLKTAIAKAGY 242 Query: 237 KPGEEIALALDAASSEFYKDGKYIVSGKE--------YTREELLELYKELTSTYPIVSIE 288 + + +D A+SEFY+ K I + KE + ++L +LYK YPIVSIE Sbjct: 243 -----VVIGMDVAASEFYEKDKDITNFKEENNDGSQKISADQLKDLYKSFVDEYPIVSIE 297 Query: 289 DPFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLT 348 DPF ++DWE + +T E+G+KVQIVGDDL VTNPKR++K I+ A NALLLKVNQIG++T Sbjct: 298 DPFDQDDWEHYSKLTAEIGEKVQIVGDDLLVTNPKRVEKAIKEKACNALLLKVNQIGSVT 357 Query: 349 EAMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLI 408 E+++A M+ RAG+G V++HRSGETED IADL+V L GQIKTGAP RS+R AKYNQL+ Sbjct: 358 ESIEAVKMSKRAGWG-VMAHRSGETEDTFIADLSVGLATGQIKTGAPCRSERLAKYNQLL 416 Query: 409 RIEEELEGVAVYAGKNFR 426 RIEEEL AVYAG NFR Sbjct: 417 RIEEELGSEAVYAGANFR 434 >emb|CAC00533.1| (AJ132581) enolase, isoform 2 [Hevea brasiliensis] Length = 445 Score = 458 bits (1166), Expect = e-128 Identities = 255/437 (58%), Positives = 312/437 (71%), Gaps = 21/437 (4%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPIS-MGRAAVPSGASTGTHEAVELRDGGKRYHGKGV 67 IV+V AR+I DSRGNPTVE DV + RAAVP GASTG +EA+ELRDGG Y GKGV Sbjct: 5 IVSVRARQIFDSRGNPTVEADVKLSDGYLARAAVPRGASTGIYEALELRDGGSDYLGKGV 64 Query: 68 RRAVENVNKIIAPELVGMDVRWQREIDRLLIE-LDGTEN-----KSNLGANAILAVSLAV 121 +AVENVN II P LVG D Q ID +++ LDGT N K LGANAILAVSLAV Sbjct: 65 SKAVENVNIIIGPALVGKDPTDQVGIDNFMVQQLDGTVNEWGWCKQKLGANAILAVSLAV 124 Query: 122 AKAAANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSF 178 KA A+ +PLY++ L G VLPVP NVINGG HAGN L QEFMI+P+GA+SF Sbjct: 125 CKAGAHVKGIPLYKHVANLAGNKNLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSF 184 Query: 179 REAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKP 238 +EA++ +E YH LK VI +KYG++A NVGDEGGFAP ++E E L++L AI +AGY Sbjct: 185 KEAMKMGAEVYHHLKSVIKKKYGQDATNVGDEGGFAPNIQENKEGLELLKTAIAKAGYTG 244 Query: 239 GEEIALALDAASSEFY-KDGKYIVSGKEYTR--------EELLELYKELTSTYPIVSIED 289 ++ + +D A+SEFY D Y ++ KE + L +LYK + YPIVSIED Sbjct: 245 --KVVIGMDVAASEFYGSDKTYDLNFKEENNNGSQKISGDVLKDLYKSFVTEYPIVSIED 302 Query: 290 PFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTE 349 PF ++DWE + +T E+G KVQIVGDDL VTNPKR++K I+ A NALLLKVNQIG++TE Sbjct: 303 PFDQDDWEHYAKLTSEIGVKVQIVGDDLLVTNPKRVEKAIKEKACNALLLKVNQIGSVTE 362 Query: 350 AMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIR 409 +++A M+ RAG+GV+ SHRSGETED IADL+V L GQIKTGAP RS+R AKYNQL+R Sbjct: 363 SIEAVKMSKRAGWGVMASHRSGETEDTFIADLSVGLATGQIKTGAPCRSERLAKYNQLLR 422 Query: 410 IEEELEGVAVYAGKNFR 426 IEEEL AVYAG NFR Sbjct: 423 IEEELGAEAVYAGANFR 439 >gb|AAD41643.1|AF072586_1 (AF072586) alpha enolase [Alligator mississippiensis] Length = 434 Score = 458 bits (1165), Expect = e-128 Identities = 245/431 (56%), Positives = 309/431 (70%), Gaps = 17/431 (3%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67 I+ + AREI DSRGNPTVEVD++T + RAAVPSGASTG +EA+ELRD K R+ GKGV Sbjct: 3 ILKIHAREIFDSRGNPTVEVDLYTSKGLFRAAVPSGASTGIYEALELRDNDKTRFMGKGV 62 Query: 68 RRAVENVNKIIAPELVGMDVRW--QREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 +AV +VNK IAP L+ ++ Q +IDRL++E+DG+ENKS GANAIL VSLAV KA Sbjct: 63 SKAVAHVNKTIAPALISKNISVVEQEKIDRLMLEMDGSENKSKFGANAILGVSLAVCKAG 122 Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182 A +PLY++ L G +LPVP NVINGG HAGN L QEFMI+P+GA SF+EA+ Sbjct: 123 AAEKGVPLYRHIADLAGNPEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFKEAM 182 Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242 R +E YH LK VI EKYGK+A NVGDEGGFAP + E E L++L AI +AGY ++I Sbjct: 183 RIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKNAINKAGYS--DKI 240 Query: 243 ALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEED 295 + +D A+SEFY+DGKY + K T ++L +LYK YP+VSIEDPF ++D Sbjct: 241 VIGMDVAASEFYRDGKYDLDFKSPDDPSRYITPDQLADLYKSFVKNYPVVSIEDPFDQDD 300 Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355 W + T +G +Q+VGDDL VTNPKR+ K ++ A N LLLKVNQIG++TE++ A Sbjct: 301 WAAWKKFTASVG--IQVVGDDLTVTNPKRIAKAVDDKACNCLLLKVNQIGSVTESLQACK 358 Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415 +A G+GV+VSHRSGETED IADL V L GQIKTGAP RS+R AKYNQ++RIEEEL Sbjct: 359 LAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEELG 418 Query: 416 GVAVYAGKNFR 426 A +AG+NFR Sbjct: 419 SKARFAGRNFR 429 >sp|P08734|ENO_XENLA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|68307|pir||NOXL phosphopyruvate hydratase (EC 4.2.1.11) ENO1 - African clawed frog >gi|64680|emb|CAA68706.1| (Y00718) enolase (AA 1-434) [Xenopus laevis] Length = 434 Score = 457 bits (1164), Expect = e-128 Identities = 249/430 (57%), Positives = 307/430 (70%), Gaps = 17/430 (3%) Query: 14 AREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRAVE 72 AREI DSRGNPTVEVD++T + RAAVPSGASTG +EA+ELRD K RY GKGV RAV+ Sbjct: 8 AREIFDSRGNPTVEVDLYTCKGLFRAAVPSGASTGIYEALELRDNDKTRYLGKGVGRAVK 67 Query: 73 NVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANALE 130 VN+ + P L ++V Q +ID+L+IE+DGTENKS GANA+L VSLAV KA A Sbjct: 68 YVNEFLGPALCTQNLNVVEQEKIDKLMIEMDGTENKSKFGANALLGVSLAVCKAGAAEKG 127 Query: 131 LPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVSE 187 +PLY++ L G +LPVP NVINGG HAGN L QEFMI+P+GA+SF+EA+R +E Sbjct: 128 VPLYRHIADLAGNPEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGADSFKEAMRIGAE 187 Query: 188 TYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALALD 247 YH LK VI EKYGK+A NVGDEGGFAP + E E L++L AI +AGY ++I + +D Sbjct: 188 VYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKTAINKAGYP--DKIVIGMD 245 Query: 248 AASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEEDWEGFV 300 A+SEFY+DGKY + K + ++L ELY YP+VSIEDPF ++ WE + Sbjct: 246 VAASEFYRDGKYDLDFKSPDDPSRYISPDKLAELYMSFVKNYPVVSIEDPFDQDHWEAWT 305 Query: 301 MITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRA 360 T G +Q+VGDDL VTNPKR+ K +E A N LLLKVNQIGT+TE+++A +A Sbjct: 306 KFTAASG--IQVVGDDLTVTNPKRIAKAVEEKACNCLLLKVNQIGTVTESLEACKLAQSN 363 Query: 361 GYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVY 420 G+GV+VSHRSGETED IADL V L GQIKTGAP RS+R AKYNQL+RIEEEL A + Sbjct: 364 GWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGSKARF 423 Query: 421 AGKNFRKVFF 430 AGKNFRK F Sbjct: 424 AGKNFRKPVF 433 >sp|P51913|ENOA_CHICK ALPHA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (PHOSPHOPYRUVATE HYDRATASE) >gi|1085243|pir||JC4186 phosphopyruvate hydratase (EC 4.2.1.11) alpha chain - chicken >gi|974176|dbj|BAA07132.1| (D37900) enolase [Gallus gallus] Length = 434 Score = 456 bits (1160), Expect = e-127 Identities = 245/431 (56%), Positives = 310/431 (71%), Gaps = 17/431 (3%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67 I+ + AREI DSRGNPTVEVD++T + RAAVPSGASTG +EA+ELRD K RY GKGV Sbjct: 3 ILKIHAREIFDSRGNPTVEVDLYTNKGLFRAAVPSGASTGIYEALELRDNDKTRYLGKGV 62 Query: 68 RRAVENVNKIIAPELVGMDVRW--QREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 +AVE+VNK IAP L+ +V Q +ID+L++E+DGTENKS GANAIL VSLAV KA Sbjct: 63 SKAVEHVNKTIAPALISKNVNVVEQEKIDKLMLEMDGTENKSKFGANAILGVSLAVCKAG 122 Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182 A +PLY++ L G +LPVP NVINGG HAGN L QEFMI+P+GA++F+EA+ Sbjct: 123 AAEKGVPLYRHIADLAGNPEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGADTFKEAM 182 Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242 R +E YH LK VI EKYGK+A NVGDEGGFAP + E E L++L AI +AGY +++ Sbjct: 183 RIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKTAIGKAGYS--DKV 240 Query: 243 ALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEED 295 + +D A+SEFY+DGKY + K + ++L +LY YP+VSIEDPF ++D Sbjct: 241 VIGMDVAASEFYRDGKYDLDFKSPDDPSRYISPDQLADLYLGFVKNYPVVSIEDPFDQDD 300 Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355 W + T +G +Q+VGDDL VTNPKR+ K +E + N LLLKVNQIG++TE++ A Sbjct: 301 WAAWKKFTASVG--IQVVGDDLTVTNPKRIAKAVEEKSCNCLLLKVNQIGSVTESLQACK 358 Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415 +A G+GV+VSHRSGETED IADL V L GQIKTGAP RS+R AKYNQL+RIEEEL Sbjct: 359 LAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELG 418 Query: 416 GVAVYAGKNFR 426 A +AG+NFR Sbjct: 419 SKARFAGRNFR 429 >gb|AAD41645.1|AF072588_1 (AF072588) alpha enolase [Trachemys scripta elegans] Length = 434 Score = 455 bits (1157), Expect = e-127 Identities = 243/431 (56%), Positives = 310/431 (71%), Gaps = 17/431 (3%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67 I+ + AREI DSRGNPTVEVD++T + RAAVPSGASTG +EA+ELRD K R+ GKGV Sbjct: 3 ILKIFAREIFDSRGNPTVEVDLYTSKGLFRAAVPSGASTGIYEALELRDNDKTRFLGKGV 62 Query: 68 RRAVENVNKIIAPELVGMDVRW--QREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 +AV +VNK IAP L+ ++ Q +ID+L++E+DG+ENKS GANAIL VSLAV KA Sbjct: 63 SKAVGHVNKTIAPALISKNINVVEQEKIDKLMLEMDGSENKSKFGANAILGVSLAVCKAG 122 Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182 A +PLY++ L G +LPVP NVINGG HAGN L QEFMI+P+GA SF+EA+ Sbjct: 123 AAEKGVPLYRHIADLAGNPEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFKEAM 182 Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242 R +E YH LK VI EKYGK+A NVGDEGGFAP + E E L++L AI +AGY +++ Sbjct: 183 RIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILEDKEALELLKTAISKAGYT--DKV 240 Query: 243 ALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEED 295 + +D A+SEFY+DGKY + K T ++L +LYK +YP+VS+EDPF ++D Sbjct: 241 VIGMDVAASEFYRDGKYDLDFKSPDDPSRYITPDQLADLYKSFIKSYPLVSVEDPFDQDD 300 Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355 W + T +G VQ+VGDDL VTNPKR+ K +E + N LLL+VNQIG++TE++ A Sbjct: 301 WSAWKKFTATVG--VQVVGDDLTVTNPKRIAKPVEEKSCNCLLLQVNQIGSVTESLQACK 358 Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415 +A G+GV+VSHRSGETED IADL V L GQIKTGAP RS+R AKYNQL+RIEEEL Sbjct: 359 LAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELG 418 Query: 416 GVAVYAGKNFR 426 A +AG+NFR Sbjct: 419 SKARFAGRNFR 429 >sp|O02654|ENO_LOLPE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|1911573|gb|AAB50731.1| (S80961) enolase [Loligo pealii=squids, nervous system, Peptide, 434 aa] [Loligo pealei] Length = 434 Score = 454 bits (1156), Expect = e-127 Identities = 248/432 (57%), Positives = 309/432 (71%), Gaps = 18/432 (4%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRD-GGKRYHGKGV 67 I V +R+I DSRGNPTVEVD+ T M RAAVPSGASTG +EA+E+RD K YHGK + Sbjct: 3 IKKVHSRQIFDSRGNPTVEVDLWTDKGMFRAAVPSGASTGIYEALEMRDKDAKNYHGKTL 62 Query: 68 RRAVENVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 AV NVNKIIAP LV MD + Q +D L+ LDGTENK+ LGANAIL VSLAV KA Sbjct: 63 FNAVGNVNKIIAPALVDKKMDEKDQTAVDNFLLALDGTENKNKLGANAILGVSLAVCKAG 122 Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182 A A +PLY++ L G +LPVP NVINGG HAGN L QEFMI+P GA +F EA+ Sbjct: 123 AAAKGVPLYRHIADLAGNKEVILPVPAFNVINGGSHAGNKLAMQEFMILPTGAKNFTEAM 182 Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242 + +E YH LK VI +KYG++A NVGDEGGFAP + + E L++L AI AGY EI Sbjct: 183 KMGTEVYHHLKSVIKKKYGQDACNVGDEGGFAPNILDNKEGLELLKTAIANAGYTA--EI 240 Query: 243 ALALDAASSEFYKDGKYIVSGKE--------YTREELLELYKELTSTYPIVSIEDPFHEE 294 + +D A+SEF K+ KY + K T ++L ++YK+ YP+VSIEDPF ++ Sbjct: 241 EIGMDVAASEFCKEKKYDLDFKNPDSNPNDWLTSDQLADVYKDFVKNYPVVSIEDPFDQD 300 Query: 295 DWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAA 354 DWE + +T+++ +QIVGDDL VTNPKR++KGI++ AANALLLKVNQIG++TE++ A Sbjct: 301 DWEAYTKMTKDMD--IQIVGDDLLVTNPKRVQKGIDLKAANALLLKVNQIGSVTESIQAC 358 Query: 355 YMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEEL 414 M+ AG+GV+VSHRSGETED IADL V L GQIKTGAP RS+R AKYNQ++RIEEEL Sbjct: 359 KMSQDAGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEEL 418 Query: 415 EGVAVYAGKNFR 426 AV+AGK FR Sbjct: 419 GDKAVFAGKKFR 430 >sp|P26301|ENO1_MAIZE ENOLASE 1 (2-PHOSPHOGLYCERATE DEHYDRATASE 1) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE 1) >gi|100869|pir||S16257 phosphopyruvate hydratase (EC 4.2.1.11) - maize >gi|22273|emb|CAA39454.1| (X55981) enolase [Zea mays] Length = 446 Score = 453 bits (1154), Expect = e-126 Identities = 252/438 (57%), Positives = 307/438 (69%), Gaps = 22/438 (5%) Query: 9 IVAVIAREILDSRGNPTVEVDVH-TPISMGRAAVPSGASTGTHEAVELRDGGKRYHGKGV 67 I V AR+I DSRGNPTVEVDV + S R AVPSGASTG +EA+ELRDGG Y GKGV Sbjct: 5 ITWVKARQIFDSRGNPTVEVDVGLSDGSYARGAVPSGASTGIYEALELRDGGSDYLGKGV 64 Query: 68 RRAVENVNKIIAPELVGMDVRWQREIDRLLIE-LDGTEN-----KSNLGANAILAVSLAV 121 +AV NVN II P +VG D Q EID +++ LDGT N K LGANAILAVSLAV Sbjct: 65 LKAVSNVNNIIGPAIVGKDPTEQVEIDNFMVQQLDGTSNEWGWCKQKLGANAILAVSLAV 124 Query: 122 AKAAANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSF 178 KA A ++PLYQ+ L G VLPVP NVINGG HAGN L QEFMI+P GA+SF Sbjct: 125 CKAGAMVKKIPLYQHIANLAGNKTLVLPVPAFNVINGGSHAGNKLAMQEFMILPTGASSF 184 Query: 179 REAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKP 238 +EA++ E YH LK +I +KYG++A NVGDEGGFAP ++E E L++L AIE+AGY Sbjct: 185 KEAMKMGVEVYHNLKSIIKKKYGQDATNVGDEGGFAPNIQENKEGLELLKAAIEKAGYTG 244 Query: 239 GEEIALALDAASSEFY--KDGKYIVSGKEYTRE--------ELLELYKELTSTYPIVSIE 288 ++ + +D A+SEF+ KD Y ++ KE + L +LYK S YPI SIE Sbjct: 245 --KVVIGMDVAASEFFGEKDKTYDLNFKEENNDGSNKISGDSLKDLYKSFVSEYPIESIE 302 Query: 289 DPFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLT 348 DPF ++DW + +T E+G+KVQIVGDDL VTNP R+ K I NALLLKVNQIG++T Sbjct: 303 DPFDQDDWSTYAKLTDEIGQKVQIVGDDLLVTNPTRVAKAINEKTCNALLLKVNQIGSVT 362 Query: 349 EAMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLI 408 E+++A M+ RAG+GV+ SHRSGETED IADL+V L+ GQIKTGAP RS+R AKYNQL+ Sbjct: 363 ESIEAVRMSKRAGWGVMASHRSGETEDTFIADLSVGLSTGQIKTGAPCRSERLAKYNQLL 422 Query: 409 RIEEELEGVAVYAGKNFR 426 RIEEEL AVYAG FR Sbjct: 423 RIEEELGDAAVYAGAKFR 440 >sp|P19140|ENOA_ANAPL ALPHA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (TAU-CRYSTALLIN) >gi|86046|pir||A32132 phosphopyruvate hydratase (EC 4.2.1.11) alpha - duck >gi|62456|emb|CAA32409.1| (X14195) tau-crystallin/ alpha-enolase [Anas platyrhynchos] >gi|213091|gb|AAA49218.1| (M20749) tau-crystallin/alpha-enolase (EC 4.2.1.11) [Anas platyrhynchos] >gi|226274|prf||1504281A tau crystallin [Anas platyrhynchos] Length = 434 Score = 453 bits (1154), Expect = e-126 Identities = 245/431 (56%), Positives = 309/431 (70%), Gaps = 17/431 (3%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67 I+ + AREI DSRGNPTVEVD++T + RAAVPSGASTG +EA+ELRD K RY GKGV Sbjct: 3 ILKIHAREIFDSRGNPTVEVDLYTNKGLFRAAVPSGASTGIYEALELRDNDKTRYMGKGV 62 Query: 68 RRAVENVNKIIAPELVGMDVRW--QREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 +AVE++NK IAP L+ +V Q +ID+L++++DG+ENKS GANAIL VSLAV KA Sbjct: 63 SKAVEHINKTIAPALISKNVNVVEQDKIDKLMLDMDGSENKSKFGANAILGVSLAVCKAG 122 Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182 A +PLY++ L G +LPVP NVINGG HAGN L QEFMI P GA+SF+EA+ Sbjct: 123 AAEKGVPLYRHIADLAGNPEVILPVPAFNVINGGSHAGNKLAMQEFMIPPCGADSFKEAM 182 Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242 R +E YH LK VI EKYGK+A NVGDEGGFAP + E E L++L AI +AGY +++ Sbjct: 183 RIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKTAIGKAGYS--DKV 240 Query: 243 ALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEED 295 + +D A+SEFY+DGKY + K + ++L +LYK YP+VSIEDPF ++D Sbjct: 241 VIGMDVAASEFYRDGKYDLDFKSPDDPSRYISPDQLADLYKGFVKNYPVVSIEDPFDQDD 300 Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355 W + T +G +Q+VGDDL VTNPKR+ K +E A N LLLKVNQIG++TE++ A Sbjct: 301 WGAWKKFTGSVG--IQVVGDDLTVTNPKRIAKAVEEKACNCLLLKVNQIGSVTESLQACK 358 Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415 +A G+GV+VSHRSGETED IADL V L GQIKTGAP RS+R AKYNQL+RIEEEL Sbjct: 359 LAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELG 418 Query: 416 GVAVYAGKNFR 426 A +AG+NFR Sbjct: 419 SKARFAGRNFR 429 >emb|CAA76735.1| (Y17298) enolase [Cunninghamella elegans] Length = 436 Score = 453 bits (1154), Expect = e-126 Identities = 251/434 (57%), Positives = 305/434 (69%), Gaps = 19/434 (4%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGKR-YHGKGV 67 I V AR+I DSRGNPTVEV+V T + RA VPSGASTG HEA+ELRDG K Y GKGV Sbjct: 3 ITKVHARQIFDSRGNPTVEVEVTTDKGVFRAGVPSGASTGVHEALELRDGVKSDYLGKGV 62 Query: 68 RRAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 +AV NVN II ELV + V Q+ +D LI+LDGTENK LGANAIL VSLAVAKA Sbjct: 63 LKAVGNVNTIINEELVKANLSVVDQKAVDDFLIQLDGTENKEKLGANAILGVSLAVAKAG 122 Query: 126 ANALELPLYQYL----GGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREA 181 A +P Y ++ G +VLPVP NVINGG HAGN L QEFMIMP GA SF EA Sbjct: 123 AAEKGVPFYVHIADLAGSKKPFVLPVPAFNVINGGSHAGNKLAMQEFMIMPTGAKSFSEA 182 Query: 182 IRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEE 241 ++ SE YH LKKVI EKYG++A NVGDEGGFAP +++ E L++L+ AIE+AGY + Sbjct: 183 MKLGSEVYHTLKKVINEKYGQDATNVGDEGGFAPNIQDNQEGLELLVTAIEKAGYTG--K 240 Query: 242 IALALDAASSEFYKDGKYIVSGKE--------YTREELLELYKELTSTYPIVSIEDPFHE 293 I +A+D A+S+FYKDGKY + K T ++L +LY YPIVSIED F + Sbjct: 241 IKVAMDCAASDFYKDGKYDLDFKNPNSDPSTYLTGQDLTDLYNSYAGKYPIVSIEDAFDQ 300 Query: 294 EDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDA 353 +DWE + + Q+VGDDL VTNPKR+ +E A NALLLKVNQIGTLTE++ A Sbjct: 301 DDWENWAHMNASAD--YQLVGDDLTVTNPKRIATAVEKKACNALLLKVNQIGTLTESIQA 358 Query: 354 AYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEE 413 A + +AG+GV+VSHRSGETED +IA + V L GQIKTGAP RS+R AKYN+L+RIEEE Sbjct: 359 ALDSQKAGWGVMVSHRSGETEDTSIASIVVGLRTGQIKTGAPCRSERLAKYNELLRIEEE 418 Query: 414 LEGVAVYAGKNFRK 427 L A+YAG++FRK Sbjct: 419 LGDAAIYAGEHFRK 432 >sp|P42040|ENO_CLAHE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (ALLERGEN CLA H 6) (CLA H VI) Length = 440 Score = 453 bits (1154), Expect = e-126 Identities = 249/435 (57%), Positives = 310/435 (71%), Gaps = 19/435 (4%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67 I + +R + DSRGNPTVEVD+ T + RA VPSGASTG+HEA ELRDG K ++ GKGV Sbjct: 3 ISKIHSRYVYDSRGNPTVEVDIVTETGLHRAIVPSGASTGSHEACELRDGDKSKWAGKGV 62 Query: 68 RRAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 +AV NVN+IIAP L+ +DV+ Q +D L +LDGT NK+ +GANAIL VS+AVAKAA Sbjct: 63 TKAVANVNEIIAPALIKENLDVKDQAAVDAFLNKLDGTTNKTKIGANAILGVSMAVAKAA 122 Query: 126 ANALELPLYQYLGGVNA----YVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREA 181 A +PLY ++ ++ +VLPVP NV+NGG HAG L FQEFMI+P GA SF EA Sbjct: 123 AAEKRVPLYAHISDLSGTKKPFVLPVPFMNVVNGGSHAGGRLAFQEFMIVPSGAPSFTEA 182 Query: 182 IRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEE 241 +R +E Y LK + ++YG++A NVGDEGG AP ++ E LD++ AIEEAGY + Sbjct: 183 MRQGAEVYQKLKSLTKKRYGQSAGNVGDEGGVAPDIQTAEEALDLITDAIEEAGYTG--Q 240 Query: 242 IALALDAASSEFYK--DGKYIVSGKE--------YTREELLELYKELTSTYPIVSIEDPF 291 I +A+D ASSEFYK + KY + K T E+L + YK+L + YPIVSIEDPF Sbjct: 241 IKIAMDVASSEFYKADEKKYDLDFKNPDSDKSKWITYEQLADQYKQLAAKYPIVSIEDPF 300 Query: 292 HEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAM 351 E+DWE + + G QIVGDDL VTNP+ +KK IE A NALLLKVNQIGT+TEA+ Sbjct: 301 AEDDWEAWSYFYKTSGSDFQIVGDDLTVTNPEFIKKAIETKACNALLLKVNQIGTITEAI 360 Query: 352 DAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIE 411 +AA +F AG+GV+VSHRSGETED TIAD+ V L AGQIKTGAPARS+R AK NQ++RIE Sbjct: 361 NAAKDSFAAGWGVMVSHRSGETEDVTIADIVVGLRAGQIKTGAPARSERLAKLNQILRIE 420 Query: 412 EELEGVAVYAGKNFR 426 EEL AVYAG NFR Sbjct: 421 EELGDKAVYAGDNFR 435 >gi|4503571 enolase 1, (alpha); Enolase-1, alpha; phosphopyruvate hydratase; enolase 1, (alpha)-like 1 [Homo sapiens] >gi|11423101|ref|XP_001559.1| enolase 1, (alpha) [Homo sapiens] >gi|119339|sp|P06733|ENOA_HUMAN ALPHA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (NON-NEURAL ENOLASE) (NNE) (PHOSPHOPYRUVATE HYDRATASE) >gi|87368|pir||A29170 phosphopyruvate hydratase (EC 4.2.1.11) alpha - human >gi|182114|gb|AAA52387.1| (M14328) alpha enolase (EC 4.2.1.11) [Homo sapiens] >gi|1167843|emb|CAA34360.1| (X16288) alpha-enolase [Homo sapiens] Length = 434 Score = 453 bits (1153), Expect = e-126 Identities = 245/431 (56%), Positives = 308/431 (70%), Gaps = 17/431 (3%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67 I+ + AREI DSRGNPTVEVD+ T + RAAVPSGASTG +EA+ELRD K RY GKGV Sbjct: 3 ILKIHAREIFDSRGNPTVEVDLFTSKGLFRAAVPSGASTGIYEALELRDNDKTRYMGKGV 62 Query: 68 RRAVENVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 +AVE++NK IAP LV ++V Q +ID+L+IE+DGTENKS GANAIL VSLAV KA Sbjct: 63 SKAVEHINKTIAPALVSKKLNVTEQEKIDKLMIEMDGTENKSKFGANAILGVSLAVCKAG 122 Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182 A +PLY++ L G + +LPVP NVINGG HAGN L QEFMI+P+GA +FREA+ Sbjct: 123 AVEKGVPLYRHIADLAGNSEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGAANFREAM 182 Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242 R +E YH LK VI EKYGK+A NVGDEGGFAP + E E L++L AI +AGY +++ Sbjct: 183 RIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEGLELLKTAIGKAGYT--DKV 240 Query: 243 ALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEED 295 + +D A+SEF++ GKY + K + ++L +LYK YP+VSIEDPF ++D Sbjct: 241 VIGMDVAASEFFRSGKYDLDFKSPDDPSRYISPDQLADLYKSFIKDYPVVSIEDPFDQDD 300 Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355 W + T G +Q+VGDDL VTNPKR+ K + + N LLLKVNQIG++TE++ A Sbjct: 301 WGAWQKFTASAG--IQVVGDDLTVTNPKRIAKAVNEKSCNCLLLKVNQIGSVTESLQACK 358 Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415 +A G+GV+VSHRSGETED IADL V L GQIKTGAP RS+R AKYNQL+RIEEEL Sbjct: 359 LAQANGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELG 418 Query: 416 GVAVYAGKNFR 426 A +AG+NFR Sbjct: 419 SKAKFAGRNFR 429 >gb|AAF13454.1|AF205070_1 (AF205070) enolase [Mastigamoeba balamuthi] Length = 439 Score = 453 bits (1152), Expect = e-126 Identities = 246/436 (56%), Positives = 313/436 (71%), Gaps = 18/436 (4%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67 I +V AREILDSRGNPTVEVD+ T + R+AVPSGASTG +EA ELRDG K RY GKGV Sbjct: 4 IKSVFAREILDSRGNPTVEVDLTTEKGLFRSAVPSGASTGIYEACELRDGDKSRYLGKGV 63 Query: 68 RRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAAN 127 +AVENVNKI+AP+L+G+DV Q EIDRL++++DGTENK++LGANAIL S++V +AAA Sbjct: 64 LKAVENVNKILAPKLIGLDVTKQGEIDRLMLQIDGTENKTHLGANAILGCSMSVCRAAAA 123 Query: 128 ALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRW 184 LPLY+Y L G + +LP+P NVINGG HAGN L QEFMI P GA SF EA+R Sbjct: 124 FRGLPLYRYIAELSGNKSPMLPLPCFNVINGGEHAGNKLAMQEFMICPTGATSFHEALRM 183 Query: 185 VSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIAL 244 +ETYH LK VI ++YG +A NVGDEGGFAP ++ E L+++++AI++AGY +I + Sbjct: 184 AAETYHNLKLVIKKRYGMDATNVGDEGGFAPNIQANHEGLELIVEAIKQAGYTG--KIEI 241 Query: 245 ALDAASSEFY--KDGKYIVSGKE----------YTREELLELYKELTSTYPIVSIEDPFH 292 +D A+S F+ K+ KY + K + E L++LY+E TS YPI SIEDPF Sbjct: 242 GMDVAASSFWDAKESKYDLGFKVPADKKTPDMLVSGEGLIKLYEEWTSKYPIWSIEDPFD 301 Query: 293 EEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMD 352 ++DW + T + ++QIVGDDL VTNPKR+ + A NALLLK+NQIG+++EA++ Sbjct: 302 QDDWATYTRFTELIRNRIQIVGDDLLVTNPKRIVEARNKKACNALLLKLNQIGSVSEAVE 361 Query: 353 AAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEE 412 A +A +GV+VSHRSGETEDA IADL V L GQIKTGAP RS+R AKYNQL+RIEE Sbjct: 362 ACRLAREVNWGVMVSHRSGETEDAFIADLVVGLGCGQIKTGAPCRSERLAKYNQLLRIEE 421 Query: 413 ELEGVAVYAGKNFRKV 428 EL A YA K V Sbjct: 422 ELGANAHYAAKTLSGV 437 >emb|CAA57795.1| (X82400) enolase [Escherichia coli] Length = 437 Score = 453 bits (1152), Expect = e-126 Identities = 245/416 (58%), Positives = 303/416 (71%), Gaps = 11/416 (2%) Query: 8 EIVAVIAREILDSRGNPTVEVDVHTPIS-MGRAAVPSGASTGTHEAVELRDGGK-RYHGK 65 +IV +I REI+DSRGNPTVE +VH +G AA PSGASTG+ EA+ELRDG K R+ GK Sbjct: 3 KIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGK 62 Query: 66 GVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 GV +AV VN IA L+G D + Q ID+++I+LDGTE KS GANAILAVSLA AKAA Sbjct: 63 GVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTEKKSKFGANAILAVSLANAKAA 122 Query: 126 ANALELPLYQYLGGVNA----YVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREA 181 A A +PLY+++ +N Y +PVP+ N+INGG HA N++D QEFMI P+GA + +EA Sbjct: 123 AAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEA 182 Query: 182 IRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEE 241 IR SE +H L KV+ K G N VGDEGG+AP + E L V+ +A++ AGY+ G++ Sbjct: 183 IRMGSEVFHHLAKVLKAK-GMNTA-VGDEGGYAPNLGSNDEALAVIAEAVKAAGYELGKD 240 Query: 242 IALALDAASSEFYKDGKYIVSG---KEYTREELLELYKELTSTYPIVSIEDPFHEEDWEG 298 I LA+D A+SEFYKDGKY+++G K +T EE +ELT YPIVSIED E DW+G Sbjct: 241 ITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDG 300 Query: 299 FVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAF 358 F T+ LG K+Q+VGDDLFVTN K LK+GIE G AN+ L+K NQIG+LTE + A MA Sbjct: 301 FAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSYLIKFNQIGSLTETLAAIKMAK 360 Query: 359 RAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEEL 414 AGY V+SHRSGETEDATIADLAV AGQIKTG+ +RSDR AKYNQLIRIEE L Sbjct: 361 DAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEAL 416 >sp|P17182|ENOA_MOUSE ALPHA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (NON-NEURAL ENOLASE) (NNE) >gi|109803|pir||S10246 phosphopyruvate hydratase (EC 4.2.1.11) alpha - mouse >gi|55491|emb|CAA36605.1| (X52379) alpha-enolase (AA 1-434) [Mus sp.] Length = 434 Score = 451 bits (1149), Expect = e-126 Identities = 245/431 (56%), Positives = 307/431 (70%), Gaps = 17/431 (3%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67 I+ + AREI DSRGNPTVEVD++T + RAAVPSGASTG +EA+ELRD K R+ GKGV Sbjct: 3 ILRIHAREIFDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDNDKTRFMGKGV 62 Query: 68 RRAVENVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 +AVE++NK IAP LV ++V Q +ID+L+IE+DGTENKS GANAIL VSLAV KA Sbjct: 63 SQAVEHINKTIAPALVSKKVNVVEQEKIDKLMIEMDGTENKSKFGANAILGVSLAVCKAG 122 Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182 A +PLY++ L G +LPVP NVINGG HAGN L QEFMI+P+GA+SFREA+ Sbjct: 123 AVEKGVPLYRHIADLAGNPEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFREAM 182 Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242 R +E YH LK VI EKYGK+A NVGDEGGFAP + E E L++L AI +AGY +++ Sbjct: 183 RIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKTAIAKAGYT--DQV 240 Query: 243 ALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEED 295 + +D A+SEFY+ GKY + K T ++L +LYK YP+VSIEDPF ++D Sbjct: 241 VIGMDVAASEFYRSGKYDLDFKSPDDPSRYITPDQLADLYKSFVQNYPVVSIEDPFDQDD 300 Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355 W + T G +Q+VGDDL VTNPKR+ K + N LLLKVNQIG++TE++ A Sbjct: 301 WGAWQKFTASAG--IQVVGDDLTVTNPKRIAKAASEKSCNCLLLKVNQIGSVTESLQACK 358 Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415 A G+GV+VSHRSGETED IADL V L GQIKTGAP RS+R AKYNQ++RIEEEL Sbjct: 359 PAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEELG 418 Query: 416 GVAVYAGKNFR 426 A +AG++FR Sbjct: 419 SKAKFAGRSFR 429 >pir||S06756 phosphopyruvate hydratase (EC 4.2.1.11) beta - human >gi|31170|emb|CAA34513.1| (X16504) beta-enoiase (AA 1-434) [Homo sapiens] Length = 434 Score = 451 bits (1148), Expect = e-126 Identities = 245/428 (57%), Positives = 304/428 (70%), Gaps = 17/428 (3%) Query: 12 VIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRA 70 + AREILDSRGNPTVEVD+HT RAAVPSGASTG +EA+ELRDG K RY GKGV +A Sbjct: 6 IFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKGRYLGKGVLKA 65 Query: 71 VENVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANA 128 VEN+N + P L+ + V Q ++D+ +IELDGTENKS GANAIL VSLAV KA A Sbjct: 66 VENINNTLGPALLQKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAE 125 Query: 129 LELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWV 185 +PLY++ L G +LPVP NVINGG HAGN+L QEFMI+P+GA+SF+EA+R Sbjct: 126 KGVPLYRHIADLAGNPDLILPVPAFNVINGGSHAGNNLAMQEFMILPVGASSFKEAMRIG 185 Query: 186 SETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALA 245 +E YH LK VI KYGK+A NVGDEGGFAP + E E L++L AI+ AGY +++ + Sbjct: 186 AEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYP--DKVVIG 243 Query: 246 LDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEEDWEG 298 +D A+SEFY++GKY + K T E+L ELYK YP+VSIEDPF ++DW Sbjct: 244 MDVAASEFYRNGKYDLDFKSPDDPARHITGEKLGELYKSFIKNYPVVSIEDPFDQDDWAT 303 Query: 299 FVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAF 358 + G +QIVGDDL VTNPKR+ + +E A N LLLKVNQIG++TE++ A +A Sbjct: 304 WTSFLS--GVNIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQ 361 Query: 359 RAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVA 418 G+GV+VSHRSGETED IADL V L GQIKTGAP RS+R AKYNQL+RIEE L A Sbjct: 362 SNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKA 421 Query: 419 VYAGKNFR 426 ++AG+ FR Sbjct: 422 IFAGRKFR 429 >gi|4503573 enolase 3, (beta, muscle); Enolase-3, beta, muscle [Homo sapiens] >gi|34789|emb|CAA36216.1| (X51957) muscle-specific enolase [Homo sapiens] Length = 434 Score = 451 bits (1148), Expect = e-126 Identities = 245/428 (57%), Positives = 303/428 (70%), Gaps = 17/428 (3%) Query: 12 VIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRA 70 + AREILDSRGNPTVEVD+HT RAAVPSGASTG +EA+ELRDG K RY GKGV +A Sbjct: 6 IFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKGRYLGKGVLKA 65 Query: 71 VENVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANA 128 VEN+N + P L+ + V Q ++D+ +IELDGTENKS GANAIL VSLAV KA A Sbjct: 66 VENINNTLGPALLQKKLSVADQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAE 125 Query: 129 LELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWV 185 +PLY++ L G +LPVP NVINGG HAGN L QEFMI+P+GA+SF+EA+R Sbjct: 126 KGVPLYRHIADLAGNPDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEAMRIG 185 Query: 186 SETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALA 245 +E YH LK VI KYGK+A NVGDEGGFAP + E E L++L AI+ AGY +++ + Sbjct: 186 AEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYP--DKVVIG 243 Query: 246 LDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEEDWEG 298 +D A+SEFY++GKY + K T E+L ELYK YP+VSIEDPF ++DW Sbjct: 244 MDVAASEFYRNGKYDLDFKSPDDPARHITGEKLGELYKSFIKNYPVVSIEDPFDQDDWAT 303 Query: 299 FVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAF 358 + G +QIVGDDL VTNPKR+ + +E A N LLLKVNQIG++TE++ A +A Sbjct: 304 WTSFLS--GVNIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQ 361 Query: 359 RAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVA 418 G+GV+VSHRSGETED IADL V L GQIKTGAP RS+R AKYNQL+RIEE L A Sbjct: 362 SNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKA 421 Query: 419 VYAGKNFR 426 ++AG+ FR Sbjct: 422 IFAGRKFR 429 >sp|P33676|ENO_SCHJA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|349802|gb|AAA29874.1| (L23324) enolase [Schistosoma japonicum] Length = 434 Score = 451 bits (1148), Expect = e-126 Identities = 249/432 (57%), Positives = 307/432 (70%), Gaps = 18/432 (4%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRD-GGKRYHGKGV 67 I+A+ AR+I DSRGNPTVEVD+ T + RAAVPSGASTG HEA+ELRD K Y KGV Sbjct: 3 IIAIHARQIFDSRGNPTVEVDLKTAKGLFRAAVPSGASTGVHEALELRDTNSKAYMCKGV 62 Query: 68 RRAVENVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 AV NVN IIAP L+ + V Q E+D+ +IELDG ENK NLGANAIL VSLAV KA Sbjct: 63 LTAVSNVNNIIAPALLKKQIPVTNQSEVDQFMIELDGKENKGNLGANAILGVSLAVCKAG 122 Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182 A L LPLY+Y L G ++PVP NVINGG HAGN L QEFMI+P GA+SF EA+ Sbjct: 123 AAELNLPLYRYIAKLAGHKDVIMPVPAFNVINGGSHAGNKLAMQEFMILPTGASSFTEAM 182 Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242 + SE YH LK VI ++G +A NVGDEGGFAP +++ + L +L +AI+ AGY EI Sbjct: 183 QMGSEVYHNLKAVIKREFGLDACNVGDEGGFAPNIQDNMKGLQLLEEAIKIAGYTGKVEI 242 Query: 243 ALALDAASSEFYKDGKYIVSGKE--------YTREELLELYKELTSTYPIVSIEDPFHEE 294 + D A+SE+YK GKY + K + +E+ +YKE+ YPIVSIEDPF ++ Sbjct: 243 GM--DCAASEYYKKGKYDLDFKNPQSAESHWLSPDEMANVYKEMIQKYPIVSIEDPFDQD 300 Query: 295 DWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAA 354 DW+ + +T +QIVGDDL VTNPKR++K I++ A N LLLKVNQIG++TE+++A Sbjct: 301 DWDAWPKLTASTN--IQIVGDDLTVTNPKRIEKAIKVKACNCLLLKVNQIGSITESIEAC 358 Query: 355 YMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEEL 414 MA +AG+GV+VSHRSGETED IADL V L GQIKTGAP RS+R AKYNQL+RIEEEL Sbjct: 359 KMAQKAGWGVMVSHRSGETEDNFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEEL 418 Query: 415 EGVAVYAGKNFR 426 A YAGK+FR Sbjct: 419 GSTAKYAGKHFR 430 >emb|CAA59331.1| (X84907) carbonate dehydratase [Homo sapiens] Length = 434 Score = 451 bits (1148), Expect = e-126 Identities = 245/431 (56%), Positives = 307/431 (70%), Gaps = 17/431 (3%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67 I+ + AREI DSRGNPTVEVD+ T + RAAVPSGASTG +EA+ELRD K RY GKGV Sbjct: 3 ILKIHAREIFDSRGNPTVEVDLFTSKGLFRAAVPSGASTGIYEALELRDNDKTRYMGKGV 62 Query: 68 RRAVENVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 +AVE++NK IAP LV ++V Q +ID+L+IE+DGTENKS GANAIL VSLAV KA Sbjct: 63 SKAVEHINKTIAPALVSKKLNVTEQEKIDKLMIEMDGTENKSKFGANAILGVSLAVCKAG 122 Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182 A +PLY++ L G + +LPVP NVINGG HAGN L QEFMI+P+GA +FREA+ Sbjct: 123 AVEKGVPLYRHIADLAGNSEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGAANFREAM 182 Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242 R +E YH LK VI EKYGK+A NVGDEGGFAP + E E L++L AI +AGY +++ Sbjct: 183 RIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEGLELLKTAIGKAGYT--DKV 240 Query: 243 ALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEED 295 + +D A+SEF + GKY + K + ++L +LYK YP+VSIEDPF ++D Sbjct: 241 VIGMDVAASEFSRSGKYDLDFKSPDDPSRYISPDQLADLYKSFIKDYPVVSIEDPFDQDD 300 Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355 W + T G +Q+VGDDL VTNPKR+ K + + N LLLKVNQIG++TE++ A Sbjct: 301 WGAWQKFTASAG--IQVVGDDLTVTNPKRIAKAVNEKSCNCLLLKVNQIGSVTESLQACK 358 Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415 +A G+GV+VSHRSGETED IADL V L GQIKTGAP RS+R AKYNQL+RIEEEL Sbjct: 359 LAQANGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELG 418 Query: 416 GVAVYAGKNFR 426 A +AG+NFR Sbjct: 419 SKAKFAGRNFR 429 >gi|11426964 enolase 3, (beta, muscle) [Homo sapiens] >gi|416950|sp|P13929|ENOB_HUMAN BETA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (SKELETAL MUSCLE ENOLASE) (MSE) >gi|31167|emb|CAA40163.1| (X56832) muscle specific enolase [Homo sapiens] Length = 434 Score = 450 bits (1146), Expect = e-125 Identities = 245/428 (57%), Positives = 303/428 (70%), Gaps = 17/428 (3%) Query: 12 VIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRA 70 + AREILDSRGNPTVEVD+HT RAAVPSGASTG +EA+ELRDG K RY GKGV +A Sbjct: 6 IFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKGRYLGKGVLKA 65 Query: 71 VENVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANA 128 VEN+N + P L+ + V Q ++D+ +IELDGTENKS GANAIL VSLAV KA A Sbjct: 66 VENINNTLGPALLQKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAE 125 Query: 129 LELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWV 185 +PLY++ L G +LPVP NVINGG HAGN L QEFMI+P+GA+SF+EA+R Sbjct: 126 KGVPLYRHIADLAGNPDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEAMRIG 185 Query: 186 SETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALA 245 +E YH LK VI KYGK+A NVGDEGGFAP + E E L++L AI+ AGY +++ + Sbjct: 186 AEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYP--DKVVIG 243 Query: 246 LDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEEDWEG 298 +D A+SEFY++GKY + K T E+L ELYK YP+VSIEDPF ++DW Sbjct: 244 MDVAASEFYRNGKYDLDFKSPDDPARHITGEKLGELYKSFIKNYPVVSIEDPFDQDDWAT 303 Query: 299 FVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAF 358 + G +QIVGDDL VTNPKR+ + +E A N LLLKVNQIG++TE++ A +A Sbjct: 304 WTSFLS--GVNIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQ 361 Query: 359 RAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVA 418 G+GV+VSHRSGETED IADL V L GQIKTGAP RS+R AKYNQL+RIEE L A Sbjct: 362 SNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKA 421 Query: 419 VYAGKNFR 426 ++AG+ FR Sbjct: 422 IFAGRKFR 429 >sp|Q27527|ENO_CAEEL ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|7508094|pir||T25040 hypothetical protein T21B10.2 - Caenorhabditis elegans >gi|3879986|emb|CAA92692.1| (Z68318) contains similarity to Pfam domain: PF00113 (Enol-ase), Score=1030.7, E-value=0, N=1~cDNA EST EMBL:Z14384 comes from this gene~cDNA EST EMBL:T02304 comes from this gene~cDNA EST yk99b2.5 comes from this gene~cDNA EST yk55g12.5 comes from this > Length = 434 Score = 450 bits (1146), Expect = e-125 Identities = 247/432 (57%), Positives = 307/432 (70%), Gaps = 18/432 (4%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGKRYH-GKGV 67 I + AR+I DSRGNPTVEVD+ T + RAAVPSGASTG HEA+ELRDG K H GKGV Sbjct: 3 ITKIHARQIYDSRGNPTVEVDLFTEKGVFRAAVPSGASTGVHEALELRDGDKAVHLGKGV 62 Query: 68 RRAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 +AV N+N+ IAP L+ G DV Q++ID ++ LDG+ENK NLGANAIL VSLAVAKA Sbjct: 63 LKAVSNINEKIAPALIAKGFDVTAQKDIDDFMMALDGSENKGNLGANAILGVSLAVAKAG 122 Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182 A LPLY+Y L G VLPVP NVINGG HAGN L QEFMI+P+GA+SF EA+ Sbjct: 123 AVHKGLPLYKYIAELAGTGKVVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFAEAM 182 Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242 R SE YH LK I ++YG +A VGDEGGFAP +++ E LD+L AI++AGY +I Sbjct: 183 RMGSEVYHHLKAEIKKRYGLDATAVGDEGGFAPNIQDNKEGLDLLNTAIDKAGYTG--KI 240 Query: 243 ALALDAASSEFYKDGKYIV--------SGKEYTREELLELYKELTSTYPIVSIEDPFHEE 294 ++ +D A+SEF+KDGKY + S K + E+L ELY+ YP+VSIED F ++ Sbjct: 241 SIGMDVAASEFFKDGKYDLDFKNPASDSSKWLSGEQLTELYQSFIKEYPVVSIEDAFDQD 300 Query: 295 DWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAA 354 DW+ + +Q+VGDDL VTNPKR++ I+ + N LLLKVNQIG++TE+++AA Sbjct: 301 DWDNWGKFHG--ATSIQLVGDDLTVTNPKRIQTAIDKKSCNCLLLKVNQIGSVTESIEAA 358 Query: 355 YMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEEL 414 ++ G+GV+VSHRSGETED IADL V L GQIKTGAP RS+R AKYNQL+RIEEEL Sbjct: 359 KLSRANGWGVMVSHRSGETEDTFIADLVVGLATGQIKTGAPCRSERLAKYNQLLRIEEEL 418 Query: 415 EGVAVYAGKNFR 426 AVYAG NFR Sbjct: 419 GADAVYAGHNFR 430 >gb|AAD41644.1|AF072587_1 (AF072587) alpha enolase [Sceloporus undulatus] Length = 434 Score = 450 bits (1145), Expect = e-125 Identities = 244/431 (56%), Positives = 307/431 (70%), Gaps = 17/431 (3%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67 I+ + AREI DSRGNPTVEVD++T + RAAVPSGASTG +EA+ELRD K R+ GKGV Sbjct: 3 ILKLHAREIFDSRGNPTVEVDLYTNKGLFRAAVPSGASTGIYEALELRDNDKTRFLGKGV 62 Query: 68 RRAVENVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 +AVE+VNK IAP LV ++V Q +ID+L++E+DGTENKS GANAIL VSLAV KA Sbjct: 63 SKAVEHVNKTIAPALVNKKVNVVEQEKIDKLMLEMDGTENKSKFGANAILGVSLAVCKAG 122 Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182 A +PLY++ L G +LPVP NVINGG HAGN L QEFMI+P+GA +F+EA+ Sbjct: 123 AAEKGVPLYRHIADLAGNEDVILPVPAFNVINGGSHAGNKLAMQEFMILPVGAENFKEAM 182 Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242 R +E Y LK VI EKYGK+A NVGDEGGFAP + E E L++L AI +AGY ++I Sbjct: 183 RIGAEVYQNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKSAISKAGYT--DKI 240 Query: 243 ALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEED 295 + +D A+SEFY+DGKY + K T ++L +LYK YP+VSIEDPF + D Sbjct: 241 VIGMDVAASEFYRDGKYDLDFKSPDDPSRYITPDQLSDLYKGFIKNYPVVSIEDPFDQHD 300 Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355 W + T G +Q+VGDDL VTNP+R+ K +E + N LLLKVNQIG++TE++ A Sbjct: 301 WAAWKKFTASAG--IQVVGDDLTVTNPRRITKAVEEKSCNCLLLKVNQIGSVTESLQACK 358 Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415 +A G+GV+VSHRSGETED IADL V L GQIKTGAP RS+R AKYNQ++RIEEEL Sbjct: 359 LAQTNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEELG 418 Query: 416 GVAVYAGKNFR 426 +AG+NFR Sbjct: 419 SKGRFAGRNFR 429 >pir||A37210 phosphopyruvate hydratase (EC 4.2.1.11) beta - rabbit Length = 433 Score = 450 bits (1144), Expect = e-125 Identities = 246/428 (57%), Positives = 304/428 (70%), Gaps = 17/428 (3%) Query: 12 VIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRA 70 + AREILDSRGNPTVEVD+HT RAAVPSGASTG +EA+ELRDG K RY GKGV +A Sbjct: 5 IFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKSRYLGKGVLKA 64 Query: 71 VENVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANA 128 VE++NK + P L+ + V Q ++D+ +IELDGTENKS GANAIL VSLAV KA A Sbjct: 65 VEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAE 124 Query: 129 LELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWV 185 +PLY++ L G + VLPVP NVINGG HAGN L QEFMI+P+GA+SFREA+R Sbjct: 125 KGVPLYRHIADLAGNHDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFREAMRIG 184 Query: 186 SETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALA 245 +E YH LK VI KYGK+A NVGDEGGFAP + E E L++L AI+ AGY +++ + Sbjct: 185 AEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYP--DKVVIG 242 Query: 246 LDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEEDWEG 298 +D A+SEF++DGKY + K T ++L ELYK YP+VSIEDPF + DW Sbjct: 243 MDVAASEFHRDGKYDLDFKSPDDPARHITGQKLGELYKSFIKNYPVVSIEDPFDQGDWGA 302 Query: 299 FVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAF 358 + G +Q+VGDDL VTNPKR+ + +E A N LLLKVNQIG++TE++ A +A Sbjct: 303 WSRFLA--GVDIQVVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQ 360 Query: 359 RAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVA 418 G+GV+VSHRSGETED IADL V L GQIKTGAP RS+R AKYNQL+RIEE L A Sbjct: 361 SNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKA 420 Query: 419 VYAGKNFR 426 V+AG+ FR Sbjct: 421 VFAGRKFR 428 >sp|P25704|ENOB_RABIT BETA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (SKELETAL MUSCLE ENOLASE) Length = 434 Score = 450 bits (1144), Expect = e-125 Identities = 246/428 (57%), Positives = 304/428 (70%), Gaps = 17/428 (3%) Query: 12 VIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRA 70 + AREILDSRGNPTVEVD+HT RAAVPSGASTG +EA+ELRDG K RY GKGV +A Sbjct: 6 IFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKSRYLGKGVLKA 65 Query: 71 VENVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANA 128 VE++NK + P L+ + V Q ++D+ +IELDGTENKS GANAIL VSLAV KA A Sbjct: 66 VEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAE 125 Query: 129 LELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWV 185 +PLY++ L G + VLPVP NVINGG HAGN L QEFMI+P+GA+SFREA+R Sbjct: 126 KGVPLYRHIADLAGNHDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFREAMRIG 185 Query: 186 SETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALA 245 +E YH LK VI KYGK+A NVGDEGGFAP + E E L++L AI+ AGY +++ + Sbjct: 186 AEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYP--DKVVIG 243 Query: 246 LDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEEDWEG 298 +D A+SEF++DGKY + K T ++L ELYK YP+VSIEDPF + DW Sbjct: 244 MDVAASEFHRDGKYDLDFKSPDDPARHITGQKLGELYKSFIKNYPVVSIEDPFDQGDWGA 303 Query: 299 FVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAF 358 + G +Q+VGDDL VTNPKR+ + +E A N LLLKVNQIG++TE++ A +A Sbjct: 304 WSRFLA--GVDIQVVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQ 361 Query: 359 RAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVA 418 G+GV+VSHRSGETED IADL V L GQIKTGAP RS+R AKYNQL+RIEE L A Sbjct: 362 SNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKA 421 Query: 419 VYAGKNFR 426 V+AG+ FR Sbjct: 422 VFAGRKFR 429 >gi|6679651 enolase 3, beta muscle [Mus musculus] >gi|119344|sp|P21550|ENOB_MOUSE BETA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (SKELETAL MUSCLE ENOLASE) >gi|68306|pir||NOMSB phosphopyruvate hydratase (EC 4.2.1.11) beta - mouse >gi|50144|emb|CAA44540.1| (X62667) beta-enolase [Mus musculus] >gi|50847|emb|CAA40913.1| (X57747) enolase [Mus musculus] >gi|50849|emb|CAA43797.1| (X61600) enolase [Mus musculus] Length = 434 Score = 449 bits (1143), Expect = e-125 Identities = 246/428 (57%), Positives = 304/428 (70%), Gaps = 17/428 (3%) Query: 12 VIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRA 70 + AREILDSRGNPTVEVD+HT RAAVPSGASTG +EA+ELRDG K RY GKGV +A Sbjct: 6 IFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKARYLGKGVLKA 65 Query: 71 VENVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANA 128 VE++NK + P L+ + V Q ++D+ +IELDGTENKS GANAIL VSLAV KA A Sbjct: 66 VEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAE 125 Query: 129 LELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWV 185 +PLY++ L G VLPVP NVINGG HAGN L QEFMI+P+GA+SF+EA+R Sbjct: 126 KGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEAMRIG 185 Query: 186 SETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALA 245 +E YH LK VI KYGK+A NVGDEGGFAP + E E L++L AI+ AGY +++ + Sbjct: 186 AEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYP--DKVVIG 243 Query: 246 LDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEEDWEG 298 +D A+SEFY++GKY + K + E+L ELYK YP+VSIEDPF ++DW Sbjct: 244 MDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGELYKNFIQNYPVVSIEDPFDQDDWAT 303 Query: 299 FVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAF 358 + G +QIVGDDL VTNPKR+ + +E A N LLLKVNQIG++TE++ A +A Sbjct: 304 WTSFLS--GVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQ 361 Query: 359 RAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVA 418 G+GV+VSHRSGETED IADL V L GQIKTGAP RS+R AKYNQL+RIEE L A Sbjct: 362 SNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKA 421 Query: 419 VYAGKNFR 426 V+AG+ FR Sbjct: 422 VFAGRKFR 429 >emb|CAB96125.1| (AJ272111) enolase [Euglena gracilis] Length = 431 Score = 449 bits (1143), Expect = e-125 Identities = 241/431 (55%), Positives = 308/431 (70%), Gaps = 15/431 (3%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISM-GRAAVPSGASTGTHEAVELRDGGKR-YHGKG 66 I V AR+ILDSRGNPTVEVDV + GR AVPSGASTG +EAVELRDG K Y GKG Sbjct: 4 IKTVKARQILDSRGNPTVEVDVILDNGLLGRGAVPSGASTGEYEAVELRDGDKAVYLGKG 63 Query: 67 VRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAA 126 V ++VE VN I+AP+LVG+D Q +ID L+ ELDGT NK +GAN IL VS+AV +AAA Sbjct: 64 VLKSVEAVNTIVAPKLVGLDPTEQLKIDNLMRELDGTPNKGKIGANGILGVSMAVCRAAA 123 Query: 127 NALELPLYQYLG---GVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIR 183 +PLY+++G G + +PVP+ N+INGG HA N +DFQEFM+MP+GA +F E +R Sbjct: 124 LVKGVPLYRHIGDLHGNKTFQMPVPMCNIINGGKHADNKIDFQEFMVMPVGAANFSEGLR 183 Query: 184 WVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIA 243 W +E +H LK ++ K + +VGDEGGFAP + E LD +I AI+ AG++PG++IA Sbjct: 184 WCAEIFHHLKSIL--KKAGHVTSVGDEGGFAPNLDN-DEALDFVIAAIKAAGFEPGKQIA 240 Query: 244 LALDAASSEFYKDG-----KYIVSGKE--YTREELLELYKELTSTYPIVSIEDPFHEEDW 296 +ALD ASSE + +G KY S + ++ E++E Y + YPIVSIEDP + DW Sbjct: 241 IALDCASSELFDEGDRKGYKYWKSNPDRLFSAAEMIEKYAGWVAKYPIVSIEDPLDQNDW 300 Query: 297 EGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYM 356 +G+V +T++LG K+QIVGDD FVTNP R KKGIE+ A N++L+KVNQIGT++E ++ M Sbjct: 301 DGYVNMTKQLGGKIQIVGDDFFVTNPTRFKKGIELAACNSILIKVNQIGTVSETLECIKM 360 Query: 357 AFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEG 416 A AGY V SHRSGETEDA IADLAV AGQIKTG+ +R+DR AKYNQLIRIEEEL G Sbjct: 361 AQAAGYTAVASHRSGETEDAFIADLAVGTAAGQIKTGSLSRTDRMAKYNQLIRIEEELGG 420 Query: 417 VAVYAGKNFRK 427 A + RK Sbjct: 421 EAKWTTAMLRK 431 >gi|6978809 enolase 1, alpha [Rattus norvegicus] >gi|119341|sp|P04764|ENOA_RAT ALPHA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (NON-NEURAL ENOLASE) (NNE) >gi|92213|pir||A23126 phosphopyruvate hydratase (EC 4.2.1.11) alpha - rat >gi|56107|emb|CAA26456.1| (X02610) alpha-alpha enolase (NNE) [Rattus norvegicus] Length = 434 Score = 449 bits (1142), Expect = e-125 Identities = 244/431 (56%), Positives = 307/431 (70%), Gaps = 17/431 (3%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67 I+ + AREI DSRGNPTVEVD++T + RAAVPSGASTG +EA+ELRD K R+ GKGV Sbjct: 3 ILKIHAREIFDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDNDKTRFMGKGV 62 Query: 68 RRAVENVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 +AVE++NK IAP LV ++V Q +ID+L+IE+DGTENKS GANAIL VSLAV KA Sbjct: 63 SKAVEHINKTIAPALVSKKLNVVEQEKIDQLMIEMDGTENKSKFGANAILGVSLAVCKAG 122 Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182 A +PLY++ L G LPVP NVINGG HAGN L QEFMI+P+GA+SFREA+ Sbjct: 123 AVGKGVPLYRHIADLAGNPEVTLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFREAM 182 Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242 R +E YH LK VI EKYGK+A NVGDEGGFAP + E E L++L AI +AGY +++ Sbjct: 183 RIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKSAIAKAGYT--DQV 240 Query: 243 ALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEED 295 + +D A+SEFY+ GKY + K T ++L +LYK YP+VSIEDPF ++D Sbjct: 241 VIGMDVAASEFYRAGKYDLDFKSPDDASRYITPDQLADLYKSFIKDYPVVSIEDPFDQDD 300 Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355 W+ + T G +Q+VGDDL VTNPKR+ K + N LLLKVNQIG++TE++ A Sbjct: 301 WDAWQKFTATAG--IQVVGDDLTVTNPKRIAKAAGEKSCNCLLLKVNQIGSVTESLQACK 358 Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415 +A G+GV+VSHRS ETED IADL V L GQIKTGAP RS+R AKYNQ++RIEEEL Sbjct: 359 LAQSNGWGVMVSHRSEETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEELG 418 Query: 416 GVAVYAGKNFR 426 A +AG++FR Sbjct: 419 SKAKFAGRSFR 429 >gb|AAF71925.1|AF260259_1 (AF260259) beta beta enolase [Oryctolagus cuniculus] Length = 434 Score = 448 bits (1141), Expect = e-125 Identities = 245/428 (57%), Positives = 305/428 (71%), Gaps = 17/428 (3%) Query: 12 VIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRA 70 + AREILDSRGNPTVEVD+HT RAAVPSGASTG +EA+ELRDG K RY GKGV +A Sbjct: 6 IFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKSRYLGKGVLKA 65 Query: 71 VENVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANA 128 VE++NK + P L+ + V Q ++D+ +IELDGTENKS GANAIL VSLAV KA A Sbjct: 66 VEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAE 125 Query: 129 LELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWV 185 +PLY++ L G + VLPVP NVINGG HAGN L QEFMI+P+GA+SFREA+R Sbjct: 126 KGVPLYRHIADLAGNHDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFREAMRIG 185 Query: 186 SETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALA 245 +E YH LK VI KYGK+A NVGDEGGFAP + E E L++L AI+ AGY +++ + Sbjct: 186 AEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYP--DKVVIG 243 Query: 246 LDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEEDWEG 298 +D A+SEF+++GKY + K T ++L ELYK YP+VSIEDPF++ DW Sbjct: 244 MDVAASEFHRNGKYDLDFKSPDDPARHITGQKLGELYKSFIKNYPVVSIEDPFNQGDWGA 303 Query: 299 FVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAF 358 + G +Q+VGDDL VTNPKR+ + +E A N LLLKVNQIG++TE++ A +A Sbjct: 304 WSRFLA--GVDIQVVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQ 361 Query: 359 RAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVA 418 G+GV+VSHRSGETED IADL V L GQIKTGAP RS+R AKYNQL+RIEE L A Sbjct: 362 SNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKA 421 Query: 419 VYAGKNFR 426 V+AG+ FR Sbjct: 422 VFAGRKFR 429 >pir||S43113 phosphopyruvate hydratase (EC 4.2.1.11) - fungus (Cladosporium herbarum) >gi|467660|emb|CAA55070.1| (X78226) phosphopyruvate hydratase [Cladosporium herbarum] Length = 440 Score = 446 bits (1135), Expect = e-124 Identities = 246/435 (56%), Positives = 307/435 (70%), Gaps = 19/435 (4%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67 I + +R + DSRGNPTVEVD+ T + RA VPS ASTG+HEA ELRDG K ++ GKGV Sbjct: 3 ISKIHSRYVYDSRGNPTVEVDIVTETGLHRAIVPSVASTGSHEACELRDGDKSKWAGKGV 62 Query: 68 RRAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 +AV NVN+IIAP L+ +DV+ Q +D L +LDGT NK+ +GANAIL VS+AVAKAA Sbjct: 63 TKAVANVNEIIAPALIKENLDVKDQAAVDAFLNKLDGTTNKTKIGANAILGVSMAVAKAA 122 Query: 126 ANALELPLYQYLGGVNA----YVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREA 181 A +PLY ++ ++ +VLPVP NV+NGG HAG L FQEFMI+P GA SF EA Sbjct: 123 AAEKRVPLYAHISDLSGTKKPFVLPVPFMNVVNGGSHAGGRLAFQEFMIVPSGAPSFTEA 182 Query: 182 IRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEE 241 +R +E Y LK + ++YG++A NVGDEGG AP ++ E LD++ AIEEAGY + Sbjct: 183 MRQGAEVYQKLKSLTKKRYGQSAGNVGDEGGVAPDIQTAEEALDLITDAIEEAGYTG--Q 240 Query: 242 IALALDAASSEFYK--DGKYIVSGKE--------YTREELLELYKELTSTYPIVSIEDPF 291 I +A+D ASSEFYK + KY + K T E+L + Y EL + YPIVSIEDPF Sbjct: 241 IKIAMDVASSEFYKADEKKYDLDFKNPDSDKSKWITYEQLADQYNELAAKYPIVSIEDPF 300 Query: 292 HEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAM 351 E+DWE + + G QIVGDDL VTNP+ +KK IE A NALLLKVNQIGT+TEA+ Sbjct: 301 AEDDWEAWSYFYKTSGSDFQIVGDDLTVTNPEFIKKAIETKACNALLLKVNQIGTITEAI 360 Query: 352 DAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIE 411 +AA +F AG+GV+VSHRSGETED TIAD+ V L AGQIKTGAPARS+R AK NQ++RIE Sbjct: 361 NAAKDSFAAGWGVMVSHRSGETEDVTIADIVVGLRAGQIKTGAPARSERLAKLNQILRIE 420 Query: 412 EELEGVAVYAGKNFR 426 EEL +YAG NFR Sbjct: 421 EELGDKRLYAGDNFR 435 >gb|AAF36733.1| (AC016662) putative enolase; 31277-33713 [Arabidopsis thaliana] Length = 477 Score = 446 bits (1135), Expect = e-124 Identities = 240/431 (55%), Positives = 316/431 (72%), Gaps = 19/431 (4%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGKR-YHGKGV 67 + V AR+I+DSRGNPTVEVD+ T + R+AVPSGASTG +EA+ELRDG K Y GKGV Sbjct: 51 VKGVKARQIIDSRGNPTVEVDLITD-DLYRSAVPSGASTGIYEALELRDGDKSVYGGKGV 109 Query: 68 RRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAAN 127 +A++N+N+++AP+L+G+DVR Q ++D L++ELDGT NKS LGANAIL VSL+V +A A Sbjct: 110 LQAIKNINELVAPKLIGVDVRNQADVDALMLELDGTPNKSKLGANAILGVSLSVCRAGAG 169 Query: 128 ALELPLYQYL---GGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRW 184 A +PLY+++ G V+PVP NVINGG HAGN L QEFMI+P+GA SF EA + Sbjct: 170 AKGVPLYKHIQETSGTKELVMPVPAFNVINGGSHAGNSLAMQEFMILPVGATSFSEAFQM 229 Query: 185 VSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIAL 244 SE YH LK +I KYG++A NVGDEGGFAP +++ E L +LI AIE+AGY +I + Sbjct: 230 GSEVYHTLKGIIKTKYGQDACNVGDEGGFAPNVQDNREGLVLLIDAIEKAGYTG--KIKI 287 Query: 245 ALDAASSEFY-KDGKYIVSGKEY--------TREELLELYKELTSTYPIVSIEDPFHEED 295 +D A+SEF+ KDG+Y ++ K+ + E L +LY+E +PIVSIEDPF ++D Sbjct: 288 GMDVAASEFFMKDGRYDLNFKKQPNDGAHVLSAESLADLYREFIKDFPIVSIEDPFDQDD 347 Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355 W + + + +Q+VGDDL VTNPKR+ + I+ + NALLLKVNQIGT+TE++ AA Sbjct: 348 WSSWASLQSSVD--IQLVGDDLLVTNPKRIAEAIKKQSCNALLLKVNQIGTVTESIQAAL 405 Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415 + AG+GV+VSHRSGETED IADL+V L +GQIKTGAP RS+R +KYNQL+RIEEEL Sbjct: 406 DSKAAGWGVMVSHRSGETEDNFIADLSVGLASGQIKTGAPCRSERLSKYNQLLRIEEELG 465 Query: 416 GVAVYAGKNFR 426 V YAG+ FR Sbjct: 466 NVR-YAGEAFR 475 >sp|Q12560|ENO_ASPOR ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|2118302|pir||JC4542 6beta-hydroxyhyoscyamine epoxidase (EC 1.14.11.14) - Aspergillus oryzae >gi|1217828|dbj|BAA09973.1| (D63941) enolase [Aspergillus oryzae] >gi|2665456|dbj|BAA23760.1| (D64113) enolase [Aspergillus oryzae] >gi|1586931|prf||2205241A enolase [Aspergillus oryzae] Length = 438 Score = 445 bits (1132), Expect = e-124 Identities = 250/435 (57%), Positives = 305/435 (69%), Gaps = 21/435 (4%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67 I + AR + DSRGNPTVEVDV T + RA VPSGASTG HEA ELRDG K + GKGV Sbjct: 3 ITKIHARSVYDSRGNPTVEVDVVTETGLHRAIVPSGASTGQHEAHELRDGDKTHWGGKGV 62 Query: 68 RRAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 +AVENVNK IAP ++ +DV+ Q ++D L +LDG+ NKSNLGANAIL VSLA+AKA Sbjct: 63 LKAVENVNKTIAPAVIEENLDVKDQSKVDEFLKKLDGSANKSNLGANAILGVSLAIAKAG 122 Query: 126 ANALELPLYQYL----GGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREA 181 A +PLY ++ G YVLPVP NV+NGG HAG L FQEFMI+P A SF EA Sbjct: 123 AAEKGVPLYAHISDLAGTKKPYVLPVPFQNVLNGGSHAGGRLAFQEFMIVPSAAPSFSEA 182 Query: 182 IRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEE 241 +R +E Y LK + +KYG++A NVGDEGG AP ++ E LD++ +AIE+AGY + Sbjct: 183 LRQGAEVYQKLKTLAKKKYGQSAGNVGDEGGVAPDIQTAEEALDLITEAIEQAGYTG--K 240 Query: 242 IALALDAASSEFYKDG--KYIV--------SGKEYTREELLELYKELTSTYPIVSIEDPF 291 + +A+D ASSEFYK KY + S K T E+L +LYK L S YPIVSIEDPF Sbjct: 241 MKIAMDVASSEFYKADVKKYDLDFKNPDSDSSKWLTYEQLADLYKTLASKYPIVSIEDPF 300 Query: 292 HEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAM 351 E+DWE + + QIVGDDL VTNP R+KK IE A NALLLKVNQIGTLTE++ Sbjct: 301 AEDDWEAWSYFYKT--SDFQIVGDDLTVTNPLRIKKAIETKACNALLLKVNQIGTLTESI 358 Query: 352 DAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIE 411 AA ++ +GV+VSHRSGETED TIAD+AV L +GQIKTGAPARS+R AK NQ++RIE Sbjct: 359 QAAKDSYADNWGVMVSHRSGETEDVTIADIAVGLRSGQIKTGAPARSERLAKLNQILRIE 418 Query: 412 EELEGVAVYAGKNFR 426 EEL A+YAG+ FR Sbjct: 419 EELGNNAIYAGEKFR 433 >pir||T39737 enolase - fission yeast (Schizosaccharomyces pombe) >gi|4886570|emb|CAB43486.1| (AL050301) enolase [Schizosaccharomyces pombe] >gi|6579195|gb|AAA51399.2| (L37084) phosphopyruvate hydratase [Schizosaccharomyces pombe] Length = 439 Score = 444 bits (1131), Expect = e-124 Identities = 240/434 (55%), Positives = 307/434 (70%), Gaps = 19/434 (4%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67 I V AR+I DSRGNPTVEVD+ T + RA VPSGASTG EA+E+RDG K ++ GKGV Sbjct: 3 IQKVFARQIYDSRGNPTVEVDLTTETGIHRAIVPSGASTGIWEALEMRDGDKTKWGGKGV 62 Query: 68 RRAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 +AV NVN IIAP +V +DV Q+ D L++LDGTENKS LGANAIL VS+A+ +A Sbjct: 63 LKAVGNVNNIIAPAVVKANLDVTDQKAADEFLLKLDGTENKSKLGANAILGVSMAICRAG 122 Query: 126 ANALELPLYQYL----GGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREA 181 A +LPL++Y+ G YVLPVP NV+NGG HAG DL FQEFMI+P GA SF EA Sbjct: 123 AAQKKLPLWKYIAENFGTKGPYVLPVPSFNVLNGGSHAGGDLAFQEFMILPTGAPSFSEA 182 Query: 182 IRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEE 241 +RW +ETYH LK + ++YG +A NVGDEGG AP ++ E LD++++AI +AGY+ + Sbjct: 183 MRWGAETYHTLKSIAKKRYGSSAGNVGDEGGIAPDLQTPQEALDLIVEAINKAGYEG--K 240 Query: 242 IALALDAASSEFYKDGKYIVSGK--------EYTREELLELYKELTSTYPIVSIEDPFHE 293 I + LD ASSEFY DGKY + K + T ++L +LY EL+ YPIVSIEDPF + Sbjct: 241 IKIGLDVASSEFYVDGKYDLDIKAAKPKPENKLTYQQLTDLYVELSKKYPIVSIEDPFDQ 300 Query: 294 EDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDA 353 +DW + + E QIVGDDL VTN KRL+ I+ ANALLLKVNQIG++TE+++A Sbjct: 301 DDWSAWTHMKAETD--FQIVGDDLTVTNVKRLRTAIDKKCANALLLKVNQIGSVTESLNA 358 Query: 354 AYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEE 413 M++ AG+GV+VSHRSGET D I+ L V + AGQ+K+GAP RS+R AKYN+L+RIEEE Sbjct: 359 VRMSYEAGWGVMVSHRSGETADTFISHLTVGIGAGQLKSGAPCRSERLAKYNELLRIEEE 418 Query: 414 LEGVAVYAGKNFRK 427 L VYAG + K Sbjct: 419 LGSEGVYAGAHAGK 432 >sp|Q27877|ENO_SCHMA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|1002610|gb|AAC46884.1| (U33177) enolase [Schistosoma mansoni] >gi|1002616|gb|AAC46886.1| (U30175) enolase [Schistosoma mansoni] Length = 434 Score = 443 bits (1126), Expect = e-123 Identities = 247/432 (57%), Positives = 303/432 (69%), Gaps = 18/432 (4%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRD-GGKRYHGKGV 67 I+ + AR+I DSRGNPTVEVD+ T + RAAVPSGASTG HEA+ELRD K Y KGV Sbjct: 3 ILTIHARQIFDSRGNPTVEVDLKTSKGLFRAAVPSGASTGVHEALELRDTNSKAYMKKGV 62 Query: 68 RRAVENVNKIIAPELVGMD--VRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 AV NVNKIIAP L+ + V Q ID+ +I+LDGTENK LGANAIL VSLAV KA Sbjct: 63 LTAVSNVNKIIAPALINKNIPVTNQAAIDKYMIDLDGTENKEKLGANAILGVSLAVCKAG 122 Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182 A LPLY+Y L G ++PVP NVINGG HAGN L QEFMI+P GA+SF EA+ Sbjct: 123 AAEAGLPLYRYIARLAGHEDVIMPVPAFNVINGGSHAGNKLAMQEFMILPTGASSFTEAM 182 Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242 + +E YH LK VI +YG +A NVGDEGGFAP +++ + L +L +AI+ AGY EI Sbjct: 183 QIGTEVYHNLKAVIKREYGLDACNVGDEGGFAPNIQDNMKGLQLLEEAIKIAGYTGKVEI 242 Query: 243 ALALDAASSEFYKDGKYIVSGKE--------YTREELLELYKELTSTYPIVSIEDPFHEE 294 + D A+SEF+K+GKY + K + + + +YK++ S +PIVSIEDPF ++ Sbjct: 243 GM--DCAASEFHKNGKYDLDFKNPHSAESTWLSPDAMANMYKQMISKFPIVSIEDPFDQD 300 Query: 295 DWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAA 354 DWE + +T +QIVGDDL VTNPKR+K+ I A N LLLKVNQIG+LTE+++A Sbjct: 301 DWETWPKLTSSTN--IQIVGDDLTVTNPKRIKQAIASKACNCLLLKVNQIGSLTESIEAC 358 Query: 355 YMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEEL 414 +A +G+GV+VSHRSGETED IADL V L GQIKTGAP RSDR AKYNQL+RIEEEL Sbjct: 359 KLAQDSGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSDRLAKYNQLLRIEEEL 418 Query: 415 EGVAVYAGKNFR 426 A YAGKNFR Sbjct: 419 GTAAKYAGKNFR 430 >gb|AAC78141.1| (AF100985) phosphopyruvate hydratase [Penaeus monodon] Length = 434 Score = 442 bits (1125), Expect = e-123 Identities = 241/435 (55%), Positives = 304/435 (69%), Gaps = 21/435 (4%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67 I V AR I DSRGNPTVEVD++T + RAAVPSGASTG HEA+E+RDG K +YHGK V Sbjct: 3 ITKVFARTIFDSRGNPTVEVDLYTHKGLFRAAVPSGASTGVHEALEMRDGDKSKYHGKSV 62 Query: 68 RRAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 +AV NVN IIAPE++ G+ V Q+E D + +LDGTENKS LGANAIL VSLA+ KA Sbjct: 63 FKAVNNVNSIIAPEIIKSGLKVTQQKECDDFMCKLDGTENKSRLGANAILGVSLAICKAG 122 Query: 126 ANALELPLYQYLGGVNAY---VLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182 A L +PLY+++ + Y +LPVP NVINGG HAGN L QEFMI+P GA SF EA+ Sbjct: 123 AAELGIPLYRHIANLANYSDVILPVPAFNVINGGSHAGNKLAMQEFMILPTGATSFTEAM 182 Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242 R SE YH LK VI ++G +A VGDEGGFAP + + L ++ ++IE+AGY +I Sbjct: 183 RMGSEVYHHLKAVIKGRFGLDATAVGDEGGFAPNILNNKDALTLIQESIEKAGYTG--KI 240 Query: 243 ALALDAASSEFYKDGKYIVS----------GKEYTREELLELYKELTSTYPIVSIEDPFH 292 + +D A+SEFYK G+ I ++ T ++L ++Y E +PIVSIEDPF Sbjct: 241 EIGMDVAASEFYK-GENIYDLDFKTANNDGSQKITGDQLRDMYMEFCKEFPIVSIEDPFD 299 Query: 293 EEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMD 352 ++DWE + +T +QIVGDDL VTNPKR+ +E A N LLLKVNQIG++TE++D Sbjct: 300 QDDWENWTKMTS--ATNIQIVGDDLTVTNPKRIATAVEKKACNCLLLKVNQIGSVTESID 357 Query: 353 AAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEE 412 A +A + G+G +VSHRSGETED IADL V L GQIKTGAP RS+R AKYNQ++RIEE Sbjct: 358 AHLLAKKNGWGTMVSHRSGETEDCFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEE 417 Query: 413 ELEGVAVYAGKNFRK 427 EL G A +AGK FRK Sbjct: 418 ELGGNAKFAGKKFRK 432 >sp|Q9ZMS6|ENO_HELPJ ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|7436886|pir||H71967 enolase - Helicobacter pylori (strain J99) >gi|4154655|gb|AAD05723.1| (AE001453) ENOLASE [Helicobacter pylori J99] Length = 426 Score = 441 bits (1123), Expect = e-123 Identities = 232/419 (55%), Positives = 299/419 (70%), Gaps = 8/419 (1%) Query: 14 AREILDSRGNPTVEVDVH-TPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRAV 71 A E++DSRGNPT++ V + + A VPSGASTG EA+ELRD K R+ GKGV RA Sbjct: 9 ALEVMDSRGNPTIQASVILSDNTKASAIVPSGASTGKREALELRDNDKTRFLGKGVLRAC 68 Query: 72 ENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANALEL 131 ENVN +I L+G++ Q +D L LDGT N +NLGANA+L VS+A+A+A+A AL L Sbjct: 69 ENVNSVIKHHLIGLEATNQAFVDERLRALDGTPNYANLGANAVLGVSMALARASAKALNL 128 Query: 132 PLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVSETYHV 191 PLY+YLGG NA LPVP+ N+INGG HA N +DFQE+MIMP+G SF+EA+R +E YH Sbjct: 129 PLYRYLGGANALTLPVPMLNIINGGTHANNSIDFQEYMIMPLGFESFKEALRASAEVYHT 188 Query: 192 LKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALALDAASS 251 LKK++ EK +VGDEGGFAP EPL+++ +AIE+AGYK GEEIALALD ASS Sbjct: 189 LKKLLDEK--NQLTSVGDEGGFAPNFNNNVEPLEIISQAIEKAGYKLGEEIALALDVASS 246 Query: 252 EFYKDG-KYIVSG--KEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMITRELGK 308 E + Y + G K EL+ YKEL + YPIVSIED E+DWEG+ +++ELG+ Sbjct: 247 ELVDEHFNYHLKGENKILDSHELVAYYKELVAKYPIVSIEDGLSEDDWEGWAFLSKELGR 306 Query: 309 KVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYGVVVSH 368 ++Q+VGDDLFVTN L+KGIE ANA+L+K NQIGT++E ++ +A Y V+SH Sbjct: 307 QIQLVGDDLFVTNASILQKGIEKNVANAILIKPNQIGTISETLETIRLAKHHAYQCVISH 366 Query: 369 RSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAGKNFRK 427 RSGE+ED+ IAD AVALN G+IKTG+ ARS+R AKYN+L+ IE EL+G +Y GK K Sbjct: 367 RSGESEDSFIADFAVALNTGEIKTGSTARSERIAKYNRLLEIEHELKG-GIYIGKELFK 424 >gb|AAD33073.1|AF149256_1 (AF149256) alpha enolase [Bos taurus] Length = 434 Score = 441 bits (1123), Expect = e-123 Identities = 240/431 (55%), Positives = 300/431 (68%), Gaps = 17/431 (3%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67 I+ V AREI DSRGNPTVEVD+ T + RAAVPSGASTG +EA+ELRD K RY GKGV Sbjct: 3 ILKVHAREIFDSRGNPTVEVDLFTAKGLFRAAVPSGASTGIYEALELRDNDKTRYMGKGV 62 Query: 68 RRAVENVNKIIAPELVGM--DVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 +AVE++NK IAP LV +V Q +ID+L+IE+DGTE KS GANAIL VSLAV KA Sbjct: 63 SKAVEHINKTIAPALVSKKSNVVEQEKIDKLMIEMDGTEKKSKFGANAILGVSLAVCKAG 122 Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182 A +PLY++ L G +LPVP NVINGG HAGN L QEFMI+P+GA +FREA+ Sbjct: 123 AVEKGVPLYRHIADLAGNAEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGAENFREAM 182 Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242 R +E YH LK VI EKYGK+A NVGDEGGFAP + E E L++L AI +AGY +++ Sbjct: 183 RIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKNAIGKAGYS--DKV 240 Query: 243 ALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEED 295 + +D A+SEFY+ GKY + K T +EL LYK YP+VSIEDPF ++D Sbjct: 241 VIGMDVAASEFYRSGKYDLDFKSPDDPSRYITPDELANLYKSFIRDYPVVSIEDPFDQDD 300 Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355 WE + T G +Q+VGDDL VT PK + KG+ + N LLLKVNQ G++TE++ Sbjct: 301 WEAWQKFTASAG--IQVVGDDLTVTTPKTIAKGVNEKSCNCLLLKVNQNGSVTESLQGCK 358 Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415 +A G+GV+VSHRSGET+D IA+L V L GQIK G P R++R AKYNQ++RIEEEL Sbjct: 359 LAHANGWGVMVSHRSGETDDTFIAELVVGLCTGQIKNGPPCRTERLAKYNQILRIEEELG 418 Query: 416 GVAVYAGKNFR 426 A +AG+NFR Sbjct: 419 SKAKFAGRNFR 429 >gb|AAF73201.1|AF152348_1 (AF152348) enolase [Trypanosoma brucei brucei] Length = 429 Score = 441 bits (1123), Expect = e-123 Identities = 238/417 (57%), Positives = 299/417 (71%), Gaps = 13/417 (3%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67 I V RE+LDSRGNPTVEV+V T + R+AVPSGASTG +EA ELRDG K RY GKG Sbjct: 3 IQKVHGREVLDSRGNPTVEVEVTTERGVFRSAVPSGASTGVYEACELRDGDKKRYVGKGC 62 Query: 68 RRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAAN 127 +AV+NVN++I P L+G D Q E+D L++ LDGT NK LGANAIL S+A++KAAA Sbjct: 63 LQAVKNVNEVIGPALIGRDELKQEELDTLMLRLDGTPNKGKLGANAILGCSMAISKAAAA 122 Query: 128 ALELPLYQYLG---GVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRW 184 A +PLY+YL G LPVP NVINGG HAGN L FQEFMI P+ A SF EA+R Sbjct: 123 AKGVPLYRYLASLAGTKELRLPVPCFNVINGGKHAGNALPFQEFMIAPVKATSFSEALRM 182 Query: 185 VSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIAL 244 SE YH L+ +I +KYG++AVNVGDEGGFAPP+K++ EPL +L++AIEEAG++ + A+ Sbjct: 183 GSEVYHSLRGIIKKKYGQDAVNVGDEGGFAPPIKDINEPLPILMEAIEEAGHRG--KFAI 240 Query: 245 ALDAASSEFYKDGK--YIVSGKE-----YTREELLELYKELTSTYPIVSIEDPFHEEDWE 297 +D A+SE Y + K Y ++ K T E+L E Y + YPIVSIEDP+ ++D+ Sbjct: 241 CMDCAASETYDEKKQQYNLTFKSPEPTWVTAEQLRETYCKWAHDYPIVSIEDPYDQDDFA 300 Query: 298 GFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMA 357 GF IT L K QIVGDDL VTN +R+K IE A N+LLLK+NQIGT++EA+ ++ + Sbjct: 301 GFAGITEALKGKTQIVGDDLTVTNTERIKMAIEKKACNSLLLKINQIGTISEAIASSKLC 360 Query: 358 FRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEEL 414 G+ V+VSHRSGETED IADL VAL +GQIKTGAP R +R AK NQL+RIEEEL Sbjct: 361 MENGWSVMVSHRSGETEDTYIADLVVALGSGQIKTGAPCRGERTAKLNQLLRIEEEL 417 >pir||E82076 enolase VC2447 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9657023|gb|AAF95589.1| (AE004314) enolase [Vibrio cholerae] Length = 433 Score = 441 bits (1123), Expect = e-123 Identities = 242/425 (56%), Positives = 303/425 (70%), Gaps = 12/425 (2%) Query: 8 EIVAVIAREILDSRGNPTVEVDVHTPIS-MGRAAVPSGASTGTHEAVELRDGGK-RYHGK 65 +IV V+ REI+DSRGNPTVE +VH +G AA PSGASTG+ EA+ELRDG K R+ GK Sbjct: 3 KIVKVLGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGK 62 Query: 66 GVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 GV +A+ VN IA LVG D + Q ID+++I+LDGTENKSN GANAILAVSLA AKAA Sbjct: 63 GVLKALAAVNGPIADALVGKDAKDQATIDQIMIDLDGTENKSNFGANAILAVSLANAKAA 122 Query: 126 ANALELPLYQYLGGVNA----YVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREA 181 A A +PLY+++ +N + +P+P+ N+INGG HA N++D QEFMI P+GA + +EA Sbjct: 123 AAAKGMPLYEHIAELNGTPGVFSMPLPMMNIINGGEHADNNVDIQEFMIQPVGAKTLKEA 182 Query: 182 IRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEE 241 +R +E +H L KV+ K G N VGDEGGFAP +K E L+V+ +A+ AGYK G + Sbjct: 183 VRMGAEVFHNLAKVLKSK-GYNTA-VGDEGGFAPNLKSNAEALEVIAEAVAAAGYKLGTD 240 Query: 242 IALALDAASSEFY----KDGKYIVSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWE 297 I LA+D A+SEFY K+ G+ +T + +ELT +PIVSIED E DWE Sbjct: 241 ITLAMDCAASEFYDAEKKEYNLKGEGRIFTSNGFSDFLEELTEKFPIVSIEDGLDESDWE 300 Query: 298 GFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMA 357 GF T +LGKK+QIVGDDLFVTN K LK+GI+ G AN++L+K NQIG+LTE + A MA Sbjct: 301 GFAYQTEKLGKKIQIVGDDLFVTNTKILKRGIDNGIANSILIKFNQIGSLTETLAAIKMA 360 Query: 358 FRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGV 417 AGY V+SHRSGETEDATIADLAV AGQIKTG+ +RSDR AKYNQLIRIEE L Sbjct: 361 KDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGSR 420 Query: 418 AVYAG 422 A + G Sbjct: 421 APFNG 425 >sp|P43806|ENO_HAEIN ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|1074058|pir||E64103 phosphopyruvate hydratase (EC 4.2.1.11) - Haemophilus influenzae (strain Rd KW20) >gi|1573953|gb|AAC22590.1| (U32775) enolase (eno) [Haemophilus influenzae Rd] Length = 436 Score = 441 bits (1122), Expect = e-123 Identities = 244/418 (58%), Positives = 300/418 (71%), Gaps = 12/418 (2%) Query: 8 EIVAVIAREILDSRGNPTVEVDVHTPIS-MGRAAVPSGASTGTHEAVELRDGGK-RYHGK 65 +IV VI REI+DSRGNPTVE +VH +G AA PSGASTG+ EA+ELRDG K R+ GK Sbjct: 3 KIVKVIGREIIDSRGNPTVEAEVHLXGGFVGLAAAPSGASTGSREALELRDGDKSRFLGK 62 Query: 66 GVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 GV +AV VN IA +VG D Q EID+++I+LDGTENKSN GANAILAVSLA AKAA Sbjct: 63 GVLKAVAAVNNEIAQAIVGKDATNQAEIDQIMIDLDGTENKSNFGANAILAVSLANAKAA 122 Query: 126 ANALELPLYQYLGGVNA----YVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREA 181 A + LPLY Y+ +N Y +P+P+ N+INGG HA N++D QEFMI P+GA + REA Sbjct: 123 AASKGLPLYAYIAELNGTAGVYSMPLPMMNIINGGEHADNNVDIQEFMIQPVGAKTLREA 182 Query: 182 IRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEE 241 +R +E +H L KV+ K AV GDEGGFAP + + L + +A+E+AGY G++ Sbjct: 183 LRIGAEVFHNLAKVLKAKGMSTAV--GDEGGFAPNLASNADALACIKEAVEKAGYVLGKD 240 Query: 242 IALALDAASSEFY--KDGKYIVSG--KEYTREELLELYKELTSTYPIVSIEDPFHEEDWE 297 + LA+D ASSEFY ++G Y + G K +T +E +EL YPIVSIED E DWE Sbjct: 241 VTLAMDCASSEFYNKENGMYEMKGEGKSFTSQEFTHYLEELCKEYPIVSIEDGQDESDWE 300 Query: 298 GFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMA 357 GF T+ LG +VQ+VGDDLFVTN K LK+GIE G AN++L+K NQIG+LTE + A MA Sbjct: 301 GFAYQTKVLGDRVQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMA 360 Query: 358 FRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415 AGY V+SHRSGETEDATIADLAV AGQIKTG+ +RSDR AKYNQLIRIEE LE Sbjct: 361 KDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRIAKYNQLIRIEEALE 418 >sp|P42448|ENO_CAMJE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|11268976|pir||E81264 phosphopyruvate hydratase (EC 4.2.1.11) Cj1672c [imported] - Campylobacter jejuni (strain NCTC 11168) >gi|6969088|emb|CAB73659.1| (AL139079) enolase [Campylobacter jejuni] Length = 414 Score = 441 bits (1122), Expect = e-123 Identities = 231/403 (57%), Positives = 296/403 (73%), Gaps = 5/403 (1%) Query: 12 VIAREILDSRGNPTVEVDVH-TPISMGRAAVPSGASTGTHEAVELRDGGKRYHGKGVRRA 70 V A E+LDSRGNPTV+ +V + S+G A VPSGASTG+ EA+ELRD +R+ GKGV +A Sbjct: 7 VRAYEVLDSRGNPTVKAEVTLSDGSVGAAIVPSGASTGSKEALELRDNDERFGGKGVLKA 66 Query: 71 VENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANALE 130 V NVN+ IA E++G+D Q ++D L ELDGT N SNLGANA L VS+A A+AAA AL Sbjct: 67 VANVNETIADEILGLDAFNQTQLDDTLRELDGTNNYSNLGANATLGVSMATARAAAAALG 126 Query: 131 LPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVSETYH 190 +PLY+YLGG NA +LPVP+ N+INGG HA N++DFQEFMIMP G SF+EA+R V E Y Sbjct: 127 MPLYRYLGGANASILPVPMCNIINGGAHANNNVDFQEFMIMPFGFTSFKEALRSVCEIYA 186 Query: 191 VLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALALDAAS 250 +LKK +A A +GDEGGFAP + TEP+D+L+ I++AGY+ + +ALD AS Sbjct: 187 ILKKELANSGHSTA--LGDEGGFAPNLANNTEPIDLLMTCIKKAGYE--NRVKIALDVAS 242 Query: 251 SEFYKDGKYIVSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMITRELGKKV 310 +EF+KDGKY + GK ++ E L+E Y EL + YPI SIED E D+EG++ +T +LG K+ Sbjct: 243 TEFFKDGKYHMEGKAFSSEALIERYVELCAKYPICSIEDGLAENDFEGWIKLTEKLGNKI 302 Query: 311 QIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYGVVVSHRS 370 Q+VGDDLFVTN L++GI ANA+L+K NQIGT+T+ M +A R Y V+SHRS Sbjct: 303 QLVGDDLFVTNEDILREGIIKKMANAVLIKPNQIGTITQTMRTVRLAQRNNYKCVMSHRS 362 Query: 371 GETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEE 413 GE+EDA IAD AVALN GQIKTGA AR +R AKYN+L+ IE E Sbjct: 363 GESEDAFIADFAVALNTGQIKTGALARGERTAKYNRLLEIEFE 405 >pir||F82700 enolase XF1291 [imported] - Xylella fastidiosa (strain 9a5c) >gi|9106280|gb|AAF84100.1|AE003962_10 (AE003962) enolase [Xylella fastidiosa] Length = 461 Score = 439 bits (1118), Expect = e-122 Identities = 238/422 (56%), Positives = 298/422 (70%), Gaps = 8/422 (1%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISM-GRAAVPSGASTGTHEAVELRDGGK-RYHGKG 66 I + AREILDSRGNPT+E +V ++ GRAAVPSGASTGT EAVELRDG K RY GKG Sbjct: 35 IAKIYAREILDSRGNPTLEAEVTLENAVCGRAAVPSGASTGTKEAVELRDGDKTRYLGKG 94 Query: 67 VRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAA 126 VR AV+NVN +IA LVG D Q +D LI LDGTENK LGANA+L VSLA A A A Sbjct: 95 VRAAVDNVNGVIAAALVGFDGADQTGLDHRLINLDGTENKGRLGANALLGVSLATAHAVA 154 Query: 127 NALELPLYQYLG--GVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRW 184 A + PL+ YL G + LPVP+ N+INGG HA N++DFQEFM++P+G SF EA+R Sbjct: 155 AARKQPLWMYLSTLGESKVSLPVPMMNIINGGAHADNNVDFQEFMVLPVGFASFSEALRA 214 Query: 185 VSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIAL 244 +E +H LK V+ + AV GDEGGFAP ++ E LD +++AI AGY GE++ L Sbjct: 215 GTEIFHALKSVLKGQGLSTAV--GDEGGFAPDLRSNVEALDAILEAIGRAGYIAGEDVLL 272 Query: 245 ALDAASSEFYKDGKYIVSG--KEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMI 302 LD ASSEF +GKY + G K T E+ ++ + + YPI+SIED E+DW G+ + Sbjct: 273 GLDVASSEFRDNGKYNLVGENKRLTSEQFVDFLDDWVTQYPIISIEDGLAEDDWAGWKQL 332 Query: 303 TRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGY 362 T +G KVQ+VGDDLFVTNPK ++GI G ANA+L+K+NQIGTLTE +++ MA RA Y Sbjct: 333 TERIGHKVQLVGDDLFVTNPKVFQEGITSGIANAILIKLNQIGTLTETLESIAMAHRAQY 392 Query: 363 GVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAG 422 +VSHRSGETED +IAD+AVA A QIKTG+ RSDR AKYNQL+RIE+ L A YAG Sbjct: 393 AAIVSHRSGETEDTSIADIAVATTATQIKTGSLCRSDRVAKYNQLLRIEQALGVGARYAG 452 Query: 423 KN 424 ++ Sbjct: 453 RD 454 >pdb|1PDZ| Mol_id: 1; Molecule: Enolase; Chain: Null; Synonym: 2-Phospho-D-Glycerate Dehydratase; Ec: 4.2.1.11; Heterogen: Phosphoglycolate; Heterogen: Mn 2+ >gi|1311142|pdb|1PDY| Mol_id: 1; Molecule: Enolase; Chain: Null; Synonym: 2-Phospho-D-Glycerate Dehydratase; Ec: 4.2.1.11 Length = 434 Score = 439 bits (1117), Expect = e-122 Identities = 239/438 (54%), Positives = 303/438 (68%), Gaps = 29/438 (6%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67 I V AR I DSRGNPTVEVD++T + RAAVPSGASTG HEA+E+RDG K +YHGK V Sbjct: 3 ITKVFARTIFDSRGNPTVEVDLYTSKGLFRAAVPSGASTGVHEALEMRDGDKSKYHGKSV 62 Query: 68 RRAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 AV+NVN +I PE++ G+ V Q+E D + +LDGTENKS+LGANAIL VSLA+ KA Sbjct: 63 FNAVKNVNDVIVPEIIKSGLKVTQQKECDEFMCKLDGTENKSSLGANAILGVSLAICKAG 122 Query: 126 ANALELPLYQYLGGVNAY---VLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182 A L +PLY+++ + Y +LPVP NVINGG HAGN L QEFMI+P GA SF EA+ Sbjct: 123 AAELGIPLYRHIANLANYDEVILPVPAFNVINGGSHAGNKLAMQEFMILPTGATSFTEAM 182 Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242 R +E YH LK VI ++G +A VGDEGGFAP + + LD++ +AI++AGY +I Sbjct: 183 RMGTEVYHHLKAVIKARFGLDATAVGDEGGFAPNILNNKDALDLIQEAIKKAGYTG--KI 240 Query: 243 ALALDAASSEFYK--------------DGKYIVSGKEYTREELLELYKELTSTYPIVSIE 288 + +D A+SEFYK DG +SG ++L ++Y E +PIVSIE Sbjct: 241 EIGMDVAASEFYKQNNIYDLDFKTANNDGSQKISG-----DQLRDMYMEFCKDFPIVSIE 295 Query: 289 DPFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLT 348 DPF ++DWE + +T G +QIVGDDL VTNPKR+ +E A LLLKVNQIG++T Sbjct: 296 DPFDQDDWETWSKMTS--GTTIQIVGDDLTVTNPKRITTAVEKKACKCLLLKVNQIGSVT 353 Query: 349 EAMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLI 408 E++DA +A + G+G +VSHRSGETED IADL V L GQIKTGAP RS+R AKYNQ++ Sbjct: 354 ESIDAHLLAKKNGWGTMVSHRSGETEDCFIADLVVGLCTGQIKTGAPCRSERLAKYNQIL 413 Query: 409 RIEEELEGVAVYAGKNFR 426 RIEEEL A +AGKNFR Sbjct: 414 RIEEELGSGAKFAGKNFR 431 >sp|P56252|ENO_HOMGA ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) Length = 433 Score = 439 bits (1117), Expect = e-122 Identities = 239/438 (54%), Positives = 303/438 (68%), Gaps = 29/438 (6%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67 I V AR I DSRGNPTVEVD++T + RAAVPSGASTG HEA+E+RDG K +YHGK V Sbjct: 2 ITKVFARTIFDSRGNPTVEVDLYTSKGLFRAAVPSGASTGVHEALEMRDGDKSKYHGKSV 61 Query: 68 RRAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 AV+NVN +I PE++ G+ V Q+E D + +LDGTENKS+LGANAIL VSLA+ KA Sbjct: 62 FNAVKNVNDVIVPEIIKSGLKVTQQKECDEFMCKLDGTENKSSLGANAILGVSLAICKAG 121 Query: 126 ANALELPLYQYLGGVNAY---VLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182 A L +PLY+++ + Y +LPVP NVINGG HAGN L QEFMI+P GA SF EA+ Sbjct: 122 AAELGIPLYRHIANLANYDEVILPVPAFNVINGGSHAGNKLAMQEFMILPTGATSFTEAM 181 Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242 R +E YH LK VI ++G +A VGDEGGFAP + + LD++ +AI++AGY +I Sbjct: 182 RMGTEVYHHLKAVIKARFGLDATAVGDEGGFAPNILNNKDALDLIQEAIKKAGYTG--KI 239 Query: 243 ALALDAASSEFYK--------------DGKYIVSGKEYTREELLELYKELTSTYPIVSIE 288 + +D A+SEFYK DG +SG ++L ++Y E +PIVSIE Sbjct: 240 EIGMDVAASEFYKQNNIYDLDFKTANNDGSQKISG-----DQLRDMYMEFCKDFPIVSIE 294 Query: 289 DPFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLT 348 DPF ++DWE + +T G +QIVGDDL VTNPKR+ +E A LLLKVNQIG++T Sbjct: 295 DPFDQDDWETWSKMTS--GTTIQIVGDDLTVTNPKRITTAVEKKACKCLLLKVNQIGSVT 352 Query: 349 EAMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLI 408 E++DA +A + G+G +VSHRSGETED IADL V L GQIKTGAP RS+R AKYNQ++ Sbjct: 353 ESIDAHLLAKKNGWGTMVSHRSGETEDCFIADLVVGLCTGQIKTGAPCRSERLAKYNQIL 412 Query: 409 RIEEELEGVAVYAGKNFR 426 RIEEEL A +AGKNFR Sbjct: 413 RIEEELGSGAKFAGKNFR 430 >sp|P48285|ENO_HELPY ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|7436877|pir||S58684 phosphopyruvate hydratase (EC 4.2.1.11) - Helicobacter pylori (strains 26695 and others) >gi|2313236|gb|AAD07219.1| (AE000536) enolase (eno) [Helicobacter pylori 26695] Length = 426 Score = 439 bits (1116), Expect = e-122 Identities = 234/420 (55%), Positives = 301/420 (70%), Gaps = 10/420 (2%) Query: 14 AREILDSRGNPTVEVDVH-TPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRAV 71 A E++DSRGNPT++ V + + A VPSGASTG EA+ELRD K R+ GKGV RA Sbjct: 9 ALEVMDSRGNPTIQASVVLSDNTKASAIVPSGASTGKREALELRDNDKTRFLGKGVLRAC 68 Query: 72 ENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANALEL 131 ENVN +I L+G++ Q +D L LDGT N +NLGANA+L VS+A+A+A+A AL L Sbjct: 69 ENVNSVIKHHLIGLEAINQAFVDERLRALDGTPNYANLGANAVLGVSMALARASAKALNL 128 Query: 132 PLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVSETYHV 191 PLY+YLGG NA LPVP+ N+INGG HA N +DFQE+MIMP+G SF+EA+R +E YH Sbjct: 129 PLYRYLGGANALTLPVPMLNIINGGTHANNSIDFQEYMIMPLGFESFKEALRASAEVYHT 188 Query: 192 LKKVIAEKYGKNAV-NVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALALDAAS 250 LKK++ GKN + +VGDEGGFAP EPL+V+ +AIE+AGYK GEEIALALD AS Sbjct: 189 LKKLLD---GKNQLTSVGDEGGFAPNFSNNVEPLEVISQAIEKAGYKLGEEIALALDVAS 245 Query: 251 SEFYKDG-KYIVSG--KEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMITRELG 307 SE + Y + G K EL+ YKEL + YPIVSIED E+DWEG+ +++ELG Sbjct: 246 SELVDENFNYHLKGENKILDSHELVAYYKELVAKYPIVSIEDGLSEDDWEGWAFLSKELG 305 Query: 308 KKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYGVVVS 367 +++Q+VGDDLFVTN L+KGIE ANA+L+K NQIGT++E ++ +A Y V+S Sbjct: 306 RQIQLVGDDLFVTNASLLQKGIEKNIANAVLIKPNQIGTISETLETIRLAKHHAYQCVMS 365 Query: 368 HRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAGKNFRK 427 HRSGE+ED+ IAD AVALN G+IKTG+ ARS+R AKYN+L+ IE EL+G +Y GK K Sbjct: 366 HRSGESEDSFIADFAVALNTGEIKTGSTARSERIAKYNRLLEIEHELKG-GIYIGKELFK 424 >emb|CAB94039.1| (AL358652) enolase [Leishmania major] Length = 429 Score = 437 bits (1111), Expect = e-121 Identities = 236/420 (56%), Positives = 297/420 (70%), Gaps = 13/420 (3%) Query: 12 VIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRA 70 V ARE+LDSRGNPTVEV++ T + R+AVPSGASTG HEA ELRDG K RY G G +A Sbjct: 6 VYAREVLDSRGNPTVEVELMTEAGVFRSAVPSGASTGVHEACELRDGDKARYCGAGCTQA 65 Query: 71 VENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANALE 130 V+NVN+I+AP LVG + Q +D+++ ELDGT+NKS LGANAIL S+A++KAAA Sbjct: 66 VKNVNEILAPALVGKEESDQAGLDKMMCELDGTKNKSKLGANAILGCSMAISKAAAAKAG 125 Query: 131 LPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVSE 187 +PLY+Y L G LPVP NVINGG HAGN L FQEFMI P A SFREA+R SE Sbjct: 126 VPLYRYIASLAGTKDIRLPVPCFNVINGGKHAGNILPFQEFMIAPTKATSFREALRMGSE 185 Query: 188 TYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALALD 247 YH LK +I KYG++AVNVGDEGGFAPP+K + EPL +L++AIE+AG+K + A+ +D Sbjct: 186 VYHALKVIIKSKYGQDAVNVGDEGGFAPPIKHIDEPLPILMEAIEKAGHKG--KFAICMD 243 Query: 248 AASSEFYKDGK--YIVSGKE-----YTREELLELYKELTSTYPIVSIEDPFHEEDWEGFV 300 A+SE Y + Y ++ K + EL Y+ + YP+VSIEDPF E++++ F Sbjct: 244 CAASEAYDAERKMYNLTFKNPEPTYVSAAELQATYERWVAEYPLVSIEDPFAEDNFDEFS 303 Query: 301 MITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRA 360 IT+ L K QIVGDDL VTN KR+ IE A N+LLLK+NQIGT++E++ AA + Sbjct: 304 AITKALAGKAQIVGDDLTVTNVKRVTMAIEKSACNSLLLKINQIGTISESIAAAKLCMEN 363 Query: 361 GYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVY 420 G+ V+VSHRSGETED IADL+V L GQIKTGAP R +R AK NQL+RIEEE+ A Y Sbjct: 364 GWSVMVSHRSGETEDTYIADLSVGLGTGQIKTGAPCRGERTAKLNQLLRIEEEIGSTATY 423 >emb|CAB96126.1| (AJ272112) chloroplast enolase [Euglena gracilis] Length = 485 Score = 436 bits (1110), Expect = e-121 Identities = 231/429 (53%), Positives = 304/429 (70%), Gaps = 16/429 (3%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISM-GRAAVPSGASTGTHEAVELRDGGKR-YHGKG 66 I V AR+ILDSRGNPTVEVDV + GR AVPSGASTG +EAVELRDG K+ Y GKG Sbjct: 57 IKVVKARQILDSRGNPTVEVDVILDNGVVGRGAVPSGASTGEYEAVELRDGDKKVYLGKG 116 Query: 67 VRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAA 126 V ++V VN ++AP+L+G+D QREID L+ ++DGT NK +GAN IL VS+A +AAA Sbjct: 117 VLKSVNAVNTLVAPKLIGLDPANQREIDELMKQIDGTPNKGKIGANGILGVSMACCRAAA 176 Query: 127 NALELPLYQYL----GGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182 +PL++++ G + + LPVP+ N+INGG HA N +DFQEFMIMPIGA SF E + Sbjct: 177 LTQGIPLWKHIANLHGNKDNFQLPVPMCNIINGGKHADNKIDFQEFMIMPIGAKSFSEGL 236 Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242 RWV+E +H LK ++ K + +VGDEGGFAP + E L+ ++KAI+ AGY PG +I Sbjct: 237 RWVTEIFHTLKALL--KKAGHVTSVGDEGGFAPDLSN-DEALEFVMKAIKAAGYTPGTQI 293 Query: 243 ALALDAASSEFYKDG-----KYIVSG--KEYTREELLELYKELTSTYPIVSIEDPFHEED 295 +ALD ASSE + +G K+ S K ++ +E+++++ YPIVSIEDP + D Sbjct: 294 GVALDCASSELFDEGGRKGYKFWKSNPSKLFSAQEMIDIFCRWCDEYPIVSIEDPLDQND 353 Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355 W+G+V +T+++G++ QIVGDD FVTNP R KGI M A NA+L+KVNQIGT++E ++ Sbjct: 354 WDGYVNMTKKMGRRTQIVGDDFFVTNPARFSKGIGMNACNAILIKVNQIGTVSETLECIK 413 Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415 MA GYG + SHRSGETEDA IADLAV GQIKTG+ +R+DR AKYNQLIRIEEEL Sbjct: 414 MAQAHGYGSIASHRSGETEDAFIADLAVGTGCGQIKTGSLSRTDRMAKYNQLIRIEEELG 473 Query: 416 GVAVYAGKN 424 A + K+ Sbjct: 474 AQAKWTTKH 482 >pir||H83191 enolase PA3635 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9949794|gb|AAG07023.1|AE004783_8 (AE004783) enolase [Pseudomonas aeruginosa] Length = 429 Score = 436 bits (1110), Expect = e-121 Identities = 235/424 (55%), Positives = 298/424 (69%), Gaps = 10/424 (2%) Query: 8 EIVAVIAREILDSRGNPTVEVDVHTPISM-GRAAVPSGASTGTHEAVELRDGGK-RYHGK 65 +IV + RE+LDSRGNPTVE DV + G A PSGASTG+ EA+ELRDG K RY GK Sbjct: 3 KIVDIKGREVLDSRGNPTVEADVILDNGIVGSACAPSGASTGSREALELRDGDKSRYLGK 62 Query: 66 GVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 GV +AV N+N I L+G D Q+ +D +IELDGTENK+ LGANAILAVSLA AKAA Sbjct: 63 GVLKAVANINGPIRDLLLGKDAADQKALDHAMIELDGTENKAKLGANAILAVSLAAAKAA 122 Query: 126 ANALELPLYQYLGGVNA----YVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREA 181 A A +PLY ++ +N Y +PVP+ N+INGG HA N++D QEFM+ P+GA +F EA Sbjct: 123 AQAKGVPLYAHIADLNGTPGQYSMPVPMMNIINGGEHADNNVDIQEFMVQPVGAKNFAEA 182 Query: 182 IRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEE 241 +R +E +H LK V+ + G N VGDEGGFAP + + L + +A+E+AGYK G++ Sbjct: 183 LRMGAEIFHHLKAVLKAR-GLNTA-VGDEGGFAPNLSSNEDALAAIAEAVEKAGYKLGDD 240 Query: 242 IALALDAASSEFYKDGKYIVSG--KEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGF 299 + LALD ASSEF+KDGKY + G K + + LT YPI+SIED E DW G+ Sbjct: 241 VTLALDCASSEFFKDGKYDLEGEGKVFDAAGFADYLAGLTQRYPIISIEDGMDESDWAGW 300 Query: 300 VMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFR 359 +T ++G KVQ+VGDDLFVTN K LK+GIE G N++L+K NQIG+LTE ++A MA Sbjct: 301 KGLTDKIGAKVQLVGDDLFVTNTKILKEGIEKGIGNSILIKFNQIGSLTETLEAIQMAKA 360 Query: 360 AGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAV 419 AGY V+SHRSGETED+TIADLAV AGQIKTG+ RSDR +KYNQL+RIEE+L A Sbjct: 361 AGYTAVISHRSGETEDSTIADLAVGTAAGQIKTGSLCRSDRVSKYNQLLRIEEQLGAKAP 420 Query: 420 YAGK 423 Y G+ Sbjct: 421 YRGR 424 >gi|6978811 muscle specific enolase (beta beta enolose) (two splicing products) [Rattus norvegicus] >gi|119346|sp|P15429|ENOB_RAT BETA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (SKELETAL MUSCLE ENOLASE) >gi|92214|pir||S02072 phosphopyruvate hydratase (EC 4.2.1.11) beta - rat >gi|57782|emb|CAA68788.1| (Y00979) beta beta enolase (AA 1-434) [Rattus norvegicus] Length = 434 Score = 436 bits (1109), Expect = e-121 Identities = 241/428 (56%), Positives = 299/428 (69%), Gaps = 17/428 (3%) Query: 12 VIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRA 70 + AREILDSRGNPTVEVD+HT RAAVPSGASTG +EA+ELRDG K RY GKGV +A Sbjct: 6 IFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKSRYLGKGVPKA 65 Query: 71 VENVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANA 128 VE++NK + P L+ + V Q ++D+ +IELDGTENKS GANAIL VSLAV KA A Sbjct: 66 VEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAE 125 Query: 129 LELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWV 185 +PLY++ L G VLPVP NVINGG HAGN L QEFMI+P+GA F+ + R Sbjct: 126 KGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGAKLFQGSQRIG 185 Query: 186 SETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALA 245 +E YH LK VI KYGK+A NVGDEGGFAP + E E L++L AI+ AGY +++ + Sbjct: 186 AEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYP--DKVVIG 243 Query: 246 LDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEEDWEG 298 +D A+SEFY++GKY + K + E+L E YK YP+VSIEDPF ++DW Sbjct: 244 MDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGEPYKSFIKNYPVVSIEDPFDQDDWAT 303 Query: 299 FVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAF 358 + G +QIVGDDL VTNPKR+ + +E A N LLLKVNQIG++TE++ A +A Sbjct: 304 WTSFLS--GVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESILACKLAQ 361 Query: 359 RAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVA 418 G+GV+VSHRSGETED +ADL V L GQIKTGAP RS+R AKYNQL+RIEE L A Sbjct: 362 SNGWGVMVSHRSGETEDTFVADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKA 421 Query: 419 VYAGKNFR 426 V+AG+ FR Sbjct: 422 VFAGRKFR 429 >gi|6321693 enolase I; Eno1p [Saccharomyces cerevisiae] >gi|2144536|pir||NOBY phosphopyruvate hydratase (EC 4.2.1.11) 1 [validated] - yeast (Saccharomyces cerevisiae) >gi|1323462|emb|CAA97283.1| (Z73039) ORF YGR254w [Saccharomyces cerevisiae] >gi|1502357|emb|CAA67616.1| (X99228) G9160 [Saccharomyces cerevisiae] Length = 437 Score = 436 bits (1109), Expect = e-121 Identities = 242/430 (56%), Positives = 300/430 (69%), Gaps = 20/430 (4%) Query: 12 VIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRA 70 V AR + DSRGNPTVEV++ T + R+ VPSGASTG HEA+E+RDG K ++ GKGV A Sbjct: 6 VYARSVYDSRGNPTVEVELTTEKGVFRSIVPSGASTGVHEALEMRDGDKSKWMGKGVLHA 65 Query: 71 VENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANA 128 V+NVN +IAP V +DV+ Q+ +D LI LDGT NKS LGANAIL VSLA ++AAA Sbjct: 66 VKNVNDVIAPAFVKANIDVKDQKAVDDFLISLDGTANKSKLGANAILGVSLAASRAAAAE 125 Query: 129 LELPLYQYLGGVNA-----YVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIR 183 +PLY++L ++ YVLPVP NV+NGG HAG L QEFMI P GA +F EA+R Sbjct: 126 KNVPLYKHLADLSKSKTSPYVLPVPFLNVLNGGSHAGGALALQEFMIAPTGAKTFAEALR 185 Query: 184 WVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIA 243 SE YH LK + ++YG +A NVGDEGG AP ++ E LD+++ AI+ AG+ +I Sbjct: 186 IGSEVYHNLKSLTKKRYGASAGNVGDEGGVAPNIQTAEEALDLIVDAIKAAGHDG--KIK 243 Query: 244 LALDAASSEFYKDGKYIVSGKE--------YTREELLELYKELTSTYPIVSIEDPFHEED 295 + LD ASSEF+KDGKY + K T +L +LY L YPIVSIEDPF E+D Sbjct: 244 IGLDCASSEFFKDGKYDLDFKNPNSDKSKWLTGPQLADLYHSLMKRYPIVSIEDPFAEDD 303 Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355 WE + + G +QIV DDL VTNPKR+ IE AA+ALLLKVNQIGTL+E++ AA Sbjct: 304 WEAWSHFFKTAG--IQIVADDLTVTNPKRIATAIEKKAADALLLKVNQIGTLSESIKAAQ 361 Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415 +F AG+GV+VSHRSGETED IADL V L GQIKTGAPARS+R AK NQL+RIEEEL Sbjct: 362 DSFAAGWGVMVSHRSGETEDTFIADLVVGLRTGQIKTGAPARSERLAKLNQLLRIEEELG 421 Query: 416 GVAVYAGKNF 425 AV+AG+NF Sbjct: 422 DNAVFAGENF 431 >sp|P00924|ENO1_YEAST ENOLASE 1 (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|171455|gb|AAA88712.1| (J01322) enolase [Saccharomyces cerevisiae] Length = 437 Score = 436 bits (1108), Expect = e-121 Identities = 241/430 (56%), Positives = 300/430 (69%), Gaps = 20/430 (4%) Query: 12 VIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRA 70 V AR + DSRGNPTVEV++ T + R+ VPSGASTG HEA+E+RDG K ++ GKGV A Sbjct: 6 VYARSVYDSRGNPTVEVELTTEKGVFRSIVPSGASTGVHEALEMRDGDKSKWMGKGVLHA 65 Query: 71 VENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANA 128 V+NVN +IAP V +DV+ Q+ +D LI LDGT NKS LGANAIL VSLA ++AAA Sbjct: 66 VKNVNDVIAPAFVKANIDVKDQKAVDDFLISLDGTANKSKLGANAILGVSLAASRAAAAE 125 Query: 129 LELPLYQYLGGVNA-----YVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIR 183 +PLY++L ++ YVLPVP NV+NGG HAG L QEFMI P GA +F EA+R Sbjct: 126 KNVPLYKHLADLSKSKTSPYVLPVPFLNVLNGGSHAGGALALQEFMIAPTGAKTFAEALR 185 Query: 184 WVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIA 243 SE YH LK + ++YG +A NVGDEGG AP ++ E LD+++ AI+ AG+ ++ Sbjct: 186 IGSEVYHNLKSLTKKRYGASAGNVGDEGGVAPNIQTAEEALDLIVDAIKAAGHDG--KVK 243 Query: 244 LALDAASSEFYKDGKYIVSGKE--------YTREELLELYKELTSTYPIVSIEDPFHEED 295 + LD ASSEF+KDGKY + K T +L +LY L YPIVSIEDPF E+D Sbjct: 244 IGLDCASSEFFKDGKYDLDFKNPNSDKSKWLTGPQLADLYHSLMKRYPIVSIEDPFAEDD 303 Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355 WE + + G +QIV DDL VTNPKR+ IE AA+ALLLKVNQIGTL+E++ AA Sbjct: 304 WEAWSHFFKTAG--IQIVADDLTVTNPKRIATAIEKKAADALLLKVNQIGTLSESIKAAQ 361 Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415 +F AG+GV+VSHRSGETED IADL V L GQIKTGAPARS+R AK NQL+RIEEEL Sbjct: 362 DSFAAGWGVMVSHRSGETEDTFIADLVVGLRTGQIKTGAPARSERLAKLNQLLRIEEELG 421 Query: 416 GVAVYAGKNF 425 AV+AG+NF Sbjct: 422 DNAVFAGENF 431 >pdb|1ONE|A Chain A, Yeast Enolase Complexed With An Equilibrium Mixture Of 2'-Phosphoglyceate And Phosphoenolpyruvate >gi|1942653|pdb|1ONE|B Chain B, Yeast Enolase Complexed With An Equilibrium Mixture Of 2'-Phosphoglyceate And Phosphoenolpyruvate >gi|1065028|pdb|1EBH|A Chain A, Enolase (E.C.4.2.1.11) (2-Phospho-D-Glycerate Hydrolase) Complexed With Mg 2+ >gi|1065029|pdb|1EBH|B Chain B, Enolase (E.C.4.2.1.11) (2-Phospho-D-Glycerate Hydrolase) Complexed With Mg 2+ >gi|2914549|pdb|2ONE|A Chain A, Asymmetric Yeast Enolase Dimer Complexed With Resolved 2'-Phosphoglycerate And Phosphoenolpyruvate >gi|2914550|pdb|2ONE|B Chain B, Asymmetric Yeast Enolase Dimer Complexed With Resolved 2'-Phosphoglycerate And Phosphoenolpyruvate >gi|1065025|pdb|1EBG|A Chain A, Enolase (E.C.4.2.1.11) (2-Phospho-D-Glycerate Hydrolase) (Apo Form) >gi|1065026|pdb|1EBG|B Chain B, Enolase (E.C.4.2.1.11) (2-Phospho-D-Glycerate Hydrolase) (Apo Form) Length = 436 Score = 436 bits (1108), Expect = e-121 Identities = 241/430 (56%), Positives = 300/430 (69%), Gaps = 20/430 (4%) Query: 12 VIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRA 70 V AR + DSRGNPTVEV++ T + R+ VPSGASTG HEA+E+RDG K ++ GKGV A Sbjct: 5 VYARSVYDSRGNPTVEVELTTEKGVFRSIVPSGASTGVHEALEMRDGDKSKWMGKGVLHA 64 Query: 71 VENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANA 128 V+NVN +IAP V +DV+ Q+ +D LI LDGT NKS LGANAIL VSLA ++AAA Sbjct: 65 VKNVNDVIAPAFVKANIDVKDQKAVDDFLISLDGTANKSKLGANAILGVSLAASRAAAAE 124 Query: 129 LELPLYQYLGGVNA-----YVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIR 183 +PLY++L ++ YVLPVP NV+NGG HAG L QEFMI P GA +F EA+R Sbjct: 125 KNVPLYKHLADLSKSKTSPYVLPVPFLNVLNGGSHAGGALALQEFMIAPTGAKTFAEALR 184 Query: 184 WVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIA 243 SE YH LK + ++YG +A NVGDEGG AP ++ E LD+++ AI+ AG+ ++ Sbjct: 185 IGSEVYHNLKSLTKKRYGASAGNVGDEGGVAPNIQTAEEALDLIVDAIKAAGHDG--KVK 242 Query: 244 LALDAASSEFYKDGKYIVSGKE--------YTREELLELYKELTSTYPIVSIEDPFHEED 295 + LD ASSEF+KDGKY + K T +L +LY L YPIVSIEDPF E+D Sbjct: 243 IGLDCASSEFFKDGKYDLDFKNPNSDKSKWLTGPQLADLYHSLMKRYPIVSIEDPFAEDD 302 Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355 WE + + G +QIV DDL VTNPKR+ IE AA+ALLLKVNQIGTL+E++ AA Sbjct: 303 WEAWSHFFKTAG--IQIVADDLTVTNPKRIATAIEKKAADALLLKVNQIGTLSESIKAAQ 360 Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415 +F AG+GV+VSHRSGETED IADL V L GQIKTGAPARS+R AK NQL+RIEEEL Sbjct: 361 DSFAAGWGVMVSHRSGETEDTFIADLVVGLRTGQIKTGAPARSERLAKLNQLLRIEEELG 420 Query: 416 GVAVYAGKNF 425 AV+AG+NF Sbjct: 421 DNAVFAGENF 430 >pdb|4ENL| Enolase (E.C.4.2.1.11) (2-Phospho-D-Glycerate Hydrolase) (Holo) >gi|231132|pdb|5ENL| Enolase (E.C.4.2.1.11) (2-Phospho-D-Glycerate Hydrolase) Complex With 2-Phospho-D-Glyceric Acid And Calcium >gi|231208|pdb|6ENL| Enolase (E.C.4.2.1.11) (2-Phospho-D-Glycerate Hydrolase) Complex With Phosphoglycolic Acid And Zinc >gi|231253|pdb|7ENL| Enolase (E.C.4.2.1.11) (2-Phospho-D-Glycerate Hydrolase) Complex With 2-Phospho-D-Glyceric Acid And Magnesium >gi|230846|pdb|3ENL| Enolase (E.C.4.2.1.11) (2-Phospho-D-Glycerate Hydrolase) (Apo) >gi|576098|pdb|1ELS| Enolase (E.C.4.2.1.11) (2-Phospho-D-Glycerate Hydrolase) Complexed With Phosphonoacetohydroxamate And Manganese >gi|494413|pdb|1NEL| Enolase (E.C.4.2.1.11) (2-Phospho-D-Glycerate Hydrolase) Complex With Orthophosphate, Fluoride And Magnesium Length = 436 Score = 434 bits (1105), Expect = e-121 Identities = 241/430 (56%), Positives = 299/430 (69%), Gaps = 20/430 (4%) Query: 12 VIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRA 70 V AR + DSRGNPTVEV++ T + R+ VPSGASTG HEA+E+RDG K ++ GKGV A Sbjct: 5 VYARSVYDSRGNPTVEVELTTEKGVFRSIVPSGASTGVHEALEMRDGDKSKWMGKGVLHA 64 Query: 71 VENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANA 128 V+NVN +IAP V +DV Q+ +D LI LDGT NKS LGANAIL VSLA ++AAA Sbjct: 65 VKNVNDVIAPAFVKANIDVSDQKAVDDFLISLDGTANKSKLGANAILGVSLAASRAAAAE 124 Query: 129 LELPLYQYLGGVNA-----YVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIR 183 +PLY++L ++ YVLPVP NV+NGG HAG L QEFMI P GA +F EA+R Sbjct: 125 KNVPLYKHLADLSKSKTSPYVLPVPFLNVLNGGSHAGGALALQEFMIAPTGAKTFAEALR 184 Query: 184 WVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIA 243 SE YH LK + ++YG +A NVGDEGG AP ++ E LD+++ AI+ AG+ ++ Sbjct: 185 IGSEVYHNLKSLTKKRYGASAGNVGDEGGVAPNIQTAEEALDLIVDAIKAAGHDG--KVK 242 Query: 244 LALDAASSEFYKDGKYIVSGKE--------YTREELLELYKELTSTYPIVSIEDPFHEED 295 + LD ASSEF+KDGKY + K T +L +LY L YPIVSIEDPF E+D Sbjct: 243 IGLDCASSEFFKDGKYDLDFKNPNSDKSKWLTGPQLADLYHSLMKRYPIVSIEDPFAEDD 302 Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355 WE + + G +QIV DDL VTNPKR+ IE AA+ALLLKVNQIGTL+E++ AA Sbjct: 303 WEAWSHFFKTAG--IQIVADDLTVTNPKRIATAIEKKAADALLLKVNQIGTLSESIKAAQ 360 Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415 +F AG+GV+VSHRSGETED IADL V L GQIKTGAPARS+R AK NQL+RIEEEL Sbjct: 361 DSFAAGWGVMVSHRSGETEDTFIADLVVGLRTGQIKTGAPARSERLAKLNQLLRIEEELG 420 Query: 416 GVAVYAGKNF 425 AV+AG+NF Sbjct: 421 DNAVFAGENF 430 >gb|AAD02812.1| (AF063247) enolase [Pneumocystis carinii f. sp. ratti] Length = 433 Score = 433 bits (1102), Expect = e-120 Identities = 233/433 (53%), Positives = 300/433 (68%), Gaps = 19/433 (4%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGKRYHGKGVR 68 I + AR DSRGNPTVEV+V T + RA VPSGASTG HEA+ELRD G + GKGV Sbjct: 3 IFKIHARSFYDSRGNPTVEVEVTTETGVHRANVPSGASTGIHEALELRDNGSSWSGKGVT 62 Query: 69 RAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAA 126 AV NVN IIAP L+ G+D++ QR ID+ LI+LDGT NKS LGANAIL VS+A+ KAAA Sbjct: 63 LAVSNVNDIIAPSLLSAGIDIKDQRSIDKFLIDLDGTSNKSRLGANAILGVSIAICKAAA 122 Query: 127 NALELPLYQYLGGV----NAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182 +PLY++ + ++LP+P NV+NGG HAG L FQEFMI+P A +F EA+ Sbjct: 123 AEKGVPLYRHFADIADIKEPFILPLPCFNVLNGGSHAGGRLAFQEFMILPTSAVTFHEAM 182 Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242 + SE Y LKK+ ++YG +A N GDEGG AP ++ E LD+++ AIEEAGY +I Sbjct: 183 QQGSEVYSALKKLSRKRYGHSAGNAGDEGGVAPDIQTADEALDLIVTAIEEAGYTG--KI 240 Query: 243 ALALDAASSEFYKDGKYIV--------SGKEYTREELLELYKELTSTYPIVSIEDPFHEE 294 +ALD A+SEFYK+GKY + S + T +EL ++Y +L+ YPIVSIE+P + Sbjct: 241 KIALDVAASEFYKNGKYDLDFKNPESDSSQHKTSKELADIYLDLSKKYPIVSIENPVDRD 300 Query: 295 DWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAA 354 DW+ ++ ++R Q+VGDDL VTN R+ + + A N LLLK+NQIGT++E++DA Sbjct: 301 DWDAWIYVSRRA--TFQMVGDDLTVTNVSRINEAADKKACNCLLLKINQIGTISESIDAF 358 Query: 355 YMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEEL 414 AF AG+GV+VSHRSGETED IADL V L GQIKTGAP RS+R AKYNQL+RIEEEL Sbjct: 359 KTAFDAGWGVMVSHRSGETEDTVIADLVVGLGTGQIKTGAPCRSERVAKYNQLLRIEEEL 418 Query: 415 EGVAVYAGKNFRK 427 +VYA N+ K Sbjct: 419 NH-SVYASMNYIK 430 >sp|P07322|ENOB_CHICK BETA ENOLASE (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (PHOSPHOPYRUVATE HYDRATASE) >gi|1085244|pir||JC4187 phosphopyruvate hydratase (EC 4.2.1.11) beta chain - chicken >gi|1616990|dbj|BAA07133.1| (D37901) enolase [Gallus gallus] Length = 434 Score = 433 bits (1101), Expect = e-120 Identities = 238/431 (55%), Positives = 299/431 (69%), Gaps = 17/431 (3%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67 I + AREILDSRG PTVEVD+HT RAAVPSGASTG HEA+E RDG K R+ GKGV Sbjct: 3 IQKIHAREILDSRGEPTVEVDLHTAKGHFRAAVPSGASTGIHEALEPRDGDKKRFLGKGV 62 Query: 68 RRAVENVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 +AVE++NK I P L+ + V Q +ID+++IE+DGTENKS GANAIL VSLAV KA Sbjct: 63 LKAVEHINKTIGPALIEKKISVVEQEKIDKVMIEMDGTENKSKFGANAILGVSLAVCKAG 122 Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182 A +PLY++ L G +LPVP NVINGG HAGN L QEFM++P+GA SF +A+ Sbjct: 123 AAEKGVPLYRHIADLAGNTELILPVPAFNVINGGSHAGNKLAMQEFMVLPVGAASFHDAM 182 Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242 R +E YH LK VI KYGK+A NVG EGGFAP + + E L++L AI +AGY +++ Sbjct: 183 RVGAEVYHSLKGVIKAKYGKDATNVGGEGGFAPNILDNHEALELLKAAIAQAGYT--DKV 240 Query: 243 ALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEED 295 + +D A+SEF +DG+Y + K T E+L E+Y+ YP+VSIEDPF ++D Sbjct: 241 VIGMDVAASEFCRDGRYHLDFKSPPHTKRYITGEQLGEIYRGFIKDYPVVSIEDPFDQDD 300 Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355 WE + + +Q+VGDDL VTNPKR+ G E A N LLLKVNQIG++TE++ A Sbjct: 301 WEAWKRFVFHVD--IQVVGDDLTVTNPKRIAHGAEQHACNCLLLKVNQIGSVTESIQACK 358 Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415 +A G+GV+VSHRSGETED IADL V L GQIKTGAP RS+R AKYNQL+RIEE L Sbjct: 359 LAQSHGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALG 418 Query: 416 GVAVYAGKNFR 426 A +AG+ FR Sbjct: 419 DKAKFAGRKFR 429 >sp|O52191|ENO_STRTR ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|2921237|gb|AAC64907.1| (AF027167) enolase [Streptococcus thermophilus] Length = 422 Score = 432 bits (1100), Expect = e-120 Identities = 230/418 (55%), Positives = 300/418 (71%), Gaps = 13/418 (3%) Query: 1 MTMENPYEIVAVIAREILDSRGNPTVEVDVH-TPISMGRAAVPSGASTGTHEAVELRDGG 59 +T+EN + AREI DSRGNPTVEVDV T ++GRAAVPSGASTG EAVELRDGG Sbjct: 3 VTIEN------IHAREIFDSRGNPTVEVDVRLTDGTLGRAAVPSGASTGDREAVELRDGG 56 Query: 60 KRYHGKGVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSL 119 R GKGV +AV NVN I L G Q ++D L+IELDGTENKS LGANAIL VS+ Sbjct: 57 ARLQGKGVSKAVANVNGEIYEALKGQSPFNQAKLDHLMIELDGTENKSCLGANAILGVSM 116 Query: 120 AVAKAAANALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFR 179 A+ +AAAN+ ++PLY+Y GGV+ LP P NVINGGVHA + +D QEF+I P+ +SFR Sbjct: 117 AIFRAAANSEKIPLYRYFGGVDLE-LPQPFFNVINGGVHADSGIDVQEFLITPVKRDSFR 175 Query: 180 EAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPG 239 + ++ ++ YH LKK++++K K V GDEGGFAP + + +L + I+ AGY PG Sbjct: 176 DGLKKIANIYHTLKKILSDKGLKTPV--GDEGGFAPKLGTTENAIAILYQPIDSAGYFPG 233 Query: 240 EEIALALDAASSEFYKDGK--YIVSGKEYTREELLELYKELTSTYP-IVSIEDPFHEEDW 296 E+IA+A+D++S EFY D K Y GK T +ELL Y L YP ++SIED F E DW Sbjct: 234 EKIAIAIDSSSIEFYDDKKKFYRFEGKNLTSKELLTYYDNLVEKYPALISIEDGFSEHDW 293 Query: 297 EGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYM 356 EGF T+ G+K+Q+VGDD+FVTNP K+GI+ ANA+L+K+NQIGT+TE ++ + Sbjct: 294 EGFAAQTKARGQKIQLVGDDIFVTNPTIFKEGIKKNVANAILIKLNQIGTVTETIETISL 353 Query: 357 AFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEEL 414 A +AGY ++SHRSGET D+ IAD +VA++AGQIK+G+ ARS+R KYNQL+RIEE+L Sbjct: 354 ARKAGYKTMISHRSGETVDSYIADFSVAMHAGQIKSGSMARSERVEKYNQLLRIEEDL 411 >gb|AAF51344.1| (AE003585) Eno gene product [Drosophila melanogaster] Length = 433 Score = 432 bits (1099), Expect = e-120 Identities = 238/433 (54%), Positives = 298/433 (67%), Gaps = 18/433 (4%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67 I A+ AR+I DSRGNPTVEVD+ T + + RAAVPSGASTG HEA+ELRD K YHGK V Sbjct: 3 IKAIKARQIYDSRGNPTVEVDLTTELGLFRAAVPSGASTGVHEALELRDNDKANYHGKSV 62 Query: 68 RRAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 +AV +VN + PEL+ +DV Q ID +I+LDGTENKS GANAIL VSLAVAKA Sbjct: 63 LKAVGHVNDTLGPELIKANLDVVDQASIDNFMIKLDGTENKSKFGANAILGVSLAVAKAG 122 Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182 A +PLY++ L G +LPVP NVINGG HAGN L QEFMI+P GA SF EA+ Sbjct: 123 AAKKGVPLYKHIADLAGNKEIILPVPAFNVINGGSHAGNKLAMQEFMILPTGATSFTEAM 182 Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242 + SE YH LK VI K+G +A VGDEGGFAP ++ E L+++ AI +AGY +I Sbjct: 183 KMGSEVYHHLKNVIKAKFGLDATAVGDEGGFAPNIQSNKEALNLISDAIAKAGYTG--KI 240 Query: 243 ALALDAASSEFYKDGKYIVSGKE--------YTREELLELYKELTSTYPIVSIEDPFHEE 294 + +D A+SEFYKDG+Y + K ++L LY+E +PIVSIEDPF ++ Sbjct: 241 EIGMDVAASEFYKDGQYDLDFKNEKSDKSQWLPADKLANLYQEFIKDFPIVSIEDPFDQD 300 Query: 295 DWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAA 354 WE + +T +QIVGDDL VTNPKR+ +E A N LLLKVNQIGT+TE++ A Sbjct: 301 HWEAWSNLTG--CTDIQIVGDDLTVTNPKRIATAVEKKACNCLLLKVNQIGTVTESIAAH 358 Query: 355 YMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEEL 414 +A + G+G +VSHRSGETED+ I DL V L+ GQIKTGAP RS+R AKYNQ++RIEEE+ Sbjct: 359 LLAKKNGWGTMVSHRSGETEDSFIGDLVVGLSTGQIKTGAPCRSERLAKYNQILRIEEEI 418 Query: 415 EGVAVYAGKNFRK 427 +AGK+FRK Sbjct: 419 GAGVKFAGKSFRK 431 >pir||I56569 gamma enolase - human (fragment) >gi|182118|gb|AAA52388.1| (M36768) gamma enolase [Homo sapiens] Length = 408 Score = 431 bits (1097), Expect = e-120 Identities = 232/402 (57%), Positives = 292/402 (71%), Gaps = 17/402 (4%) Query: 38 RAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRAVENVNKIIAPELV--GMDVRWQREID 94 RAAVPSGASTG +EA+ELRDG K RY GKGV +AV+++N IAP L+ G+ V Q ++D Sbjct: 6 RAAVPSGASTGIYEALELRDGDKQRYLGKGVLKAVDHINSTIAPALISSGLSVVEQEKLD 65 Query: 95 RLLIELDGTENKSNLGANAILAVSLAVAKAAANALELPLYQY---LGGVNAYVLPVPLSN 151 L++ELDGTENKS GANAIL VSLAV KA A LPLY++ L G + +LPVP N Sbjct: 66 NLMLELDGTENKSKFGANAILGVSLAVCKAGAAERNLPLYRHIAQLAGNSDLILPVPAFN 125 Query: 152 VINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVSETYHVLKKVIAEKYGKNAVNVGDEG 211 VINGG HAGN L QEFMI+P+GA SFR+A+R +E YH LK VI +KYGK+A NVGDEG Sbjct: 126 VINGGSHAGNKLAMQEFMILPVGAESFRDAMRLGAEVYHTLKGVIKDKYGKDATNVGDEG 185 Query: 212 GFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALALDAASSEFYKDGKYIVSGKE------ 265 GFAP + E +E L+++ +AI++AGY E+I + +D A+SEFY+DGKY + K Sbjct: 186 GFAPNILENSEALELVKEAIDKAGYT--EKIVIGMDVAASEFYRDGKYDLDFKSPTDPSR 243 Query: 266 -YTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKR 324 T ++L LY++ YP+VSIEDPF ++DW + T +G +QIVGDDL VTNPKR Sbjct: 244 YITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVG--IQIVGDDLTVTNPKR 301 Query: 325 LKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVA 384 +++ +E A N LLLKVNQIG++TEA+ A +A G+GV+VSHRSGETED IADL V Sbjct: 302 IERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVG 361 Query: 385 LNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAGKNFR 426 L GQIKTGAP RS+R AKYNQL+RIEEEL A +AG NFR Sbjct: 362 LCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARFAGHNFR 403 >sp|P15007|ENO_DROME ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|84950|pir||S07586 phosphopyruvate hydratase (EC 4.2.1.11) - fruit fly (Drosophila melanogaster) >gi|7946|emb|CAA34895.1| (X17034) enolase (AA 1-433) [Drosophila melanogaster] Length = 433 Score = 431 bits (1096), Expect = e-120 Identities = 238/433 (54%), Positives = 297/433 (67%), Gaps = 18/433 (4%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67 I A+ AR+I DSRGNPTVEVD+ T + + RAAVPSGASTG HEA+ELRD K YHGK V Sbjct: 3 IKAIKARQIYDSRGNPTVEVDLTTELGLFRAAVPSGASTGVHEALELRDNDKANYHGKSV 62 Query: 68 RRAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 +AV +VN + PEL+ +DV Q ID +I+LDGTENKS GANAIL VSLAVAKA Sbjct: 63 LKAVGHVNDTLGPELIKANLDVVDQASIDNFMIKLDGTENKSKFGANAILGVSLAVAKAG 122 Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182 A +PLY++ L G +LPVP NVINGG HAGN L QEFMI+P GA SF EA+ Sbjct: 123 AAKKGVPLYKHIADLAGNKEIILPVPAFNVINGGSHAGNKLAMQEFMILPTGATSFTEAM 182 Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242 + SE YH LK VI K+G +A VGDEGGFAP ++ E L+++ AI +AGY +I Sbjct: 183 KMGSEVYHHLKNVIKAKFGLDATAVGDEGGFAPNIQSNKEALNLISDAIAKAGYTG--KI 240 Query: 243 ALALDAASSEFYKDGKYIVSGKE--------YTREELLELYKELTSTYPIVSIEDPFHEE 294 + +D A+SEFYKDG+Y + K ++L LYKE +PIVSIEDPF ++ Sbjct: 241 EIGMDVAASEFYKDGQYDLDFKNEKSDKSQWLPADKLANLYKEFIKDFPIVSIEDPFDQD 300 Query: 295 DWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAA 354 WE + +T +QIVGDDL VTNPKR+ +E A N LLLKVNQIGT+TE++ A Sbjct: 301 HWEAWSNLTG--CTDIQIVGDDLTVTNPKRIATAVEKKACNCLLLKVNQIGTVTESIAAH 358 Query: 355 YMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEEL 414 +A + G+G +VSHRSGETED+ I DL V L+ GQIKTGAP RS+R AKYNQ++RIEEE+ Sbjct: 359 LLAKKNGWGTMVSHRSGETEDSFIGDLVVGLSTGQIKTGAPCRSERLAKYNQILRIEEEI 418 Query: 415 EGVAVYAGKNFRK 427 +AGK+F K Sbjct: 419 GAGVKFAGKSFGK 431 >sp|P51555|ENO1_ENTHI ENOLASE 1 (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|498862|gb|AAA80166.1| (U09736) enolase [Entamoeba histolytica] Length = 436 Score = 430 bits (1095), Expect = e-119 Identities = 241/434 (55%), Positives = 294/434 (67%), Gaps = 20/434 (4%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67 I V AREILDSRGNPT+EV++ T M R+ VPSGASTG HEAVELRDG K RY GKGV Sbjct: 3 IQKVHAREILDSRGNPTIEVEITTGKGMFRSCVPSGASTGVHEAVELRDGDKKRYGGKGV 62 Query: 68 RRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAAN 127 +AVENVN II P L+G +V Q E+D ++I+LDGT NK LGANAIL S+++ +AAA Sbjct: 63 LKAVENVNTIIGPALLGKNVLNQAELDEMMIKLDGTNNKGKLGANAILGCSMSICRAAAA 122 Query: 128 ALELPLYQYLGGVNAY---VLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRW 184 LPLY+YL + + +PVP NVINGG HAGN L QEFMI P GA +F EA+R Sbjct: 123 EKGLPLYKYLAELTGHKEMTMPVPCFNVINGGAHAGNALAMQEFMICPTGATNFHEALRM 182 Query: 185 VSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIAL 244 +ETY LK VI KYG++A NVGDEGGFAP + E LD+L++AI +AGY +I + Sbjct: 183 AAETYQCLKVVIKAKYGQDATNVGDEGGFAPNVSGAREALDLLVEAIAKAGYTG--KIEI 240 Query: 245 ALDAASSEFYKD-------GKYIVSGKEYTR-----EELLELYKELTSTYPIVSIEDPFH 292 A+D A+SEFY + GK I + K+ + L+ Y + YPI SIEDPF Sbjct: 241 AMDCAASEFYNEETKKYDLGKKIPADKKDPSLVKDVDGLIAEYVDYGKHYPIASIEDPFA 300 Query: 293 EEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMD 352 E+DW + T E G QIVGDDL VTNP R++ ++ A N++L+KVNQIGTLTE Sbjct: 301 EDDWAAWNKFTVEHGN-FQIVGDDLLVTNPARVQMAMDKNACNSVLIKVNQIGTLTETFK 359 Query: 353 AAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEE 412 MA G+GV+ SHRSGETED IADL V LN QIKTGAP RS+R KYNQL+RIEE Sbjct: 360 TIKMAQEKGWGVMASHRSGETEDTFIADLVVGLNCKQIKTGAPCRSERLCKYNQLMRIEE 419 Query: 413 ELEGVAVYAGKNFR 426 EL G YAGKN+R Sbjct: 420 EL-GNIPYAGKNWR 432 >gb|AAD51128.1|AF051910_1 (AF051910) enolase [Toxoplasma gondii] Length = 444 Score = 430 bits (1095), Expect = e-119 Identities = 237/437 (54%), Positives = 309/437 (70%), Gaps = 24/437 (5%) Query: 12 VIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGG-KRYHGKGVRRA 70 ++AREILDSRGNPT+EVDV T + RAAVPSGASTG +EA+ELRD KRY GKGV A Sbjct: 7 IVAREILDSRGNPTIEVDVSTEGGVFRAAVPSGASTGIYEALELRDKDPKRYLGKGVLNA 66 Query: 71 VENVNKIIAPELVGMDVRWQREIDRLLIE-LDGTEN-----KSNLGANAILAVSLAVAKA 124 VE V + I P L+G D Q+ ID L++E LDGT+N KS LGANAIL VS+A +A Sbjct: 67 VEIVRQEIKPALLGKDPCDQKGIDMLMVEQLDGTKNEWGYSKSKLGANAILGVSIACCRA 126 Query: 125 AANALELPLYQYLGG-----VNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFR 179 A + LPLY+Y+ ++ V+PVP NVINGG HAGN L QEF+I P+GA + R Sbjct: 127 GAASKGLPLYKYIATLAGKTIDKMVMPVPFFNVINGGEHAGNGLALQEFLIAPVGAPNIR 186 Query: 180 EAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPG 239 EAIR+ SETYH LK VI KYG +A NVGDEGGFAP + E L++L++AI+ AGY+ Sbjct: 187 EAIRYGSETYHHLKNVIKNKYGLDATNVGDEGGFAPNVATAEEALNLLVEAIKAAGYEG- 245 Query: 240 EEIALALDAASSEFYK--DGKYIV--------SGKEYTREELLELYKELTSTYPIVSIED 289 +I +A DAA+SEFYK + KY + + K T E+L E+Y+ YPI+S+ED Sbjct: 246 -KIKIAFDAAASEFYKQDEKKYDLDYKCKTKNASKHLTGEKLKEVYEGWLKKYPIISVED 304 Query: 290 PFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTE 349 PF ++D+ F T+++G+K Q++GDD+ VTN R++K ++ A N LLLKVNQIG++TE Sbjct: 305 PFDQDDFASFSAFTKDVGEKTQVIGDDILVTNILRIEKALKDKACNCLLLKVNQIGSVTE 364 Query: 350 AMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIR 409 A++A +A ++G+GV VSHRSGETED+ IADL V L GQIK+G+P RS+R KYNQL+R Sbjct: 365 AIEACLLAQKSGWGVQVSHRSGETEDSFIADLVVGLRCGQIKSGSPCRSERLCKYNQLMR 424 Query: 410 IEEELEGVAVYAGKNFR 426 IEE L VYAG++FR Sbjct: 425 IEESLGADCVYAGESFR 441 >gi|6321968 enolase; Eno2p [Saccharomyces cerevisiae] >gi|119337|sp|P00925|ENO2_YEAST ENOLASE 2 (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|68309|pir||NOBY2 phosphopyruvate hydratase (EC 4.2.1.11) 2 - yeast (Saccharomyces cerevisiae) >gi|171457|gb|AAA88713.1| (J01323) enolase [Saccharomyces cerevisiae] >gi|458897|gb|AAB68019.1| (U00027) Eno2p: Enolase 2; 2-phosphoglycerate dehydratase [Saccharomyces cerevisiae] Length = 437 Score = 428 bits (1089), Expect = e-119 Identities = 238/430 (55%), Positives = 295/430 (68%), Gaps = 20/430 (4%) Query: 12 VIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRA 70 V AR + DSRGNPTVEV++ T + R+ VPSGASTG HEA+E+RD K ++ GKGV A Sbjct: 6 VYARSVYDSRGNPTVEVELTTEKGVFRSIVPSGASTGVHEALEMRDEDKSKWMGKGVMNA 65 Query: 71 VENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANA 128 V NVN +IA V +DV+ Q+ +D L+ LDGT NKS LGANAIL VS+A A+AAA Sbjct: 66 VNNVNNVIAAAFVKANLDVKDQKAVDDFLLSLDGTANKSKLGANAILGVSMAAARAAAAE 125 Query: 129 LELPLYQYLGGVNA-----YVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIR 183 +PLYQ+L ++ YVLPVP NV+NGG HAG L QEFMI P GA +F EA+R Sbjct: 126 KNVPLYQHLADLSKSKTSPYVLPVPFLNVLNGGSHAGGALALQEFMIAPTGAKTFAEAMR 185 Query: 184 WVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIA 243 SE YH LK + ++YG +A NVGDEGG AP ++ E LD+++ AI+ AG+ ++ Sbjct: 186 IGSEVYHNLKSLTKKRYGASAGNVGDEGGVAPNIQTAEEALDLIVDAIKAAGHDG--KVK 243 Query: 244 LALDAASSEFYKDGKYIVSGKE--------YTREELLELYKELTSTYPIVSIEDPFHEED 295 + LD ASSEF+KDGKY + K T EL ++Y L YPIVSIEDPF E+D Sbjct: 244 IGLDCASSEFFKDGKYDLDFKNPESDKSKWLTGVELADMYHSLMKRYPIVSIEDPFAEDD 303 Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355 WE + + G +QIV DDL VTNP R+ IE AA+ALLLKVNQIGTL+E++ AA Sbjct: 304 WEAWSHFFKTAG--IQIVADDLTVTNPARIATAIEKKAADALLLKVNQIGTLSESIKAAQ 361 Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415 +F A +GV+VSHRSGETED IADL V L GQIKTGAPARS+R AK NQL+RIEEEL Sbjct: 362 DSFAANWGVMVSHRSGETEDTFIADLVVGLRTGQIKTGAPARSERLAKLNQLLRIEEELG 421 Query: 416 GVAVYAGKNF 425 AVYAG+NF Sbjct: 422 DKAVYAGENF 431 >emb|CAC16971.1| (AL450350) enolase [Streptomyces coelicolor] Length = 434 Score = 428 bits (1089), Expect = e-119 Identities = 230/420 (54%), Positives = 293/420 (69%), Gaps = 6/420 (1%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRDGGK-RYHGKG 66 I V AR I+DSRGNPTVEVDV S+GRAAVPSGASTG EAVELRD R+HGKG Sbjct: 12 IETVTARRIIDSRGNPTVEVDVVLEDGSLGRAAVPSGASTGAREAVELRDEDPTRWHGKG 71 Query: 67 VRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAA 126 V RAV +VN IA + G D Q +D LI LDGT KS LGANA+L VSLA AKAAA Sbjct: 72 VDRAVAHVNGEIAASVRGRDAADQAGLDAALIALDGTAAKSRLGANALLGVSLAAAKAAA 131 Query: 127 NALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVS 186 A PLY+YLGG +A++LP+P+ N++NGG HA N LDFQEFMI+P+GA++F EA+R S Sbjct: 132 AARRQPLYRYLGGADAHLLPLPMMNIVNGGAHADNPLDFQEFMIVPVGADTFAEAVRMGS 191 Query: 187 ETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALAL 246 E +H L++ + ++ VGDEGGFAP ++ E LD ++ AIE GY+ G +I L + Sbjct: 192 EVFHTLRRDLLA--AGHSTGVGDEGGFAPALRTAEEALDFVVAAIERTGYRAGPDIGLVM 249 Query: 247 DAASSEFYKDGKYIVSGKEYTRE--ELLELYKELTSTYPIVSIEDPFHEEDWEGFVMITR 304 D ASSEF++DG Y +G+ R E + L YP+VSIEDP E+D +G+ +T Sbjct: 250 DPASSEFFRDGGYDYAGEGVRRSPAEHADHLAGLIDAYPVVSIEDPMAEDDLDGWRELTD 309 Query: 305 ELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYGV 364 +G + Q+ GDD+F T+ +++GI G N++L+KVNQIGTLTEA+ A AG+ V Sbjct: 310 RVGDRCQLTGDDVFCTDEALVREGIRTGVGNSVLVKVNQIGTLTEALATVATAHEAGWTV 369 Query: 365 VVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAGKN 424 V+SHRSGETED TIADLAVA GQIKTG+ +RSDR AKYN+LIRIEEEL A +AG++ Sbjct: 370 VMSHRSGETEDTTIADLAVATGCGQIKTGSLSRSDRTAKYNRLIRIEEELGASARFAGRS 429 >sp|P40370|ENO1_SCHPO ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|1076907|pir||JC4036 phosphopyruvate hydratase (EC 4.2.1.11) - fission yeast (Schizosaccharomyces pombe) >gi|535442|gb|AAA70080.1| (U13799) enolase [Schizosaccharomyces pombe] Length = 439 Score = 427 bits (1086), Expect = e-118 Identities = 233/434 (53%), Positives = 300/434 (68%), Gaps = 19/434 (4%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67 I V AR+I GNPTVEVD+ T + RA VPSGASTG EA+E+RDG K ++ GKGV Sbjct: 3 IQKVFARQIYALGGNPTVEVDLTTETGIHRAIVPSGASTGIWEALEMRDGDKTKWGGKGV 62 Query: 68 RRAVENVNKIIAPELV--GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 +AV NVN IIAP +V +DV Q+ D L++LDGTENKS LGANAIL VS+A+ +A Sbjct: 63 LKAVGNVNNIIAPAVVKANLDVTDQKAADEFLLKLDGTENKSKLGANAILGVSMAICRAG 122 Query: 126 ANALELPLYQYL----GGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREA 181 A +LPL++Y+ G YVLPVP NV+NGG HAG DL FQEFMI+P GA SF EA Sbjct: 123 AAQKKLPLWKYIAENFGTKGPYVLPVPSFNVLNGGSHAGGDLAFQEFMILPTGAPSFSEA 182 Query: 182 IRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEE 241 +RW +ETY LK + ++YG +A NVGDEGG AP ++ E LD++++AI +AGY+ + Sbjct: 183 MRWGAETYQTLKSIAKKRYGSSAGNVGDEGGIAPDLQTPQEALDLIVEAINKAGYEG--K 240 Query: 242 IALALDAASSEFYKDGKYIVSGK--------EYTREELLELYKELTSTYPIVSIEDPFHE 293 I + LD SSEFY DGKY + K + T ++L +LY EL+ YPIVSIEDPF + Sbjct: 241 IKIGLDVTSSEFYVDGKYDLDIKAAKPKPENKLTYQQLTDLYVELSKKYPIVSIEDPFDQ 300 Query: 294 EDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDA 353 +DW + + E QIVGDDL VTN KRL+ I+ ANALLLKVNQIG++TE+++ Sbjct: 301 DDWSAWTHMKAETD--FQIVGDDLTVTNVKRLRTAIDKKCANALLLKVNQIGSVTESLNV 358 Query: 354 AYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEE 413 M++ AG+GV+VSHRSG T D I+ L V + AGQ+K+GAP RS+R AKYN+L+RIEEE Sbjct: 359 VRMSYEAGWGVMVSHRSGGTADTFISHLTVGIGAGQLKSGAPCRSERLAKYNELLRIEEE 418 Query: 414 LEGVAVYAGKNFRK 427 L VYAG + K Sbjct: 419 LGSRGVYAGAHAGK 432 >pir||A23850 phosphopyruvate hydratase (EC 4.2.1.11), skeletal muscle - chicken Length = 433 Score = 426 bits (1084), Expect = e-118 Identities = 234/431 (54%), Positives = 298/431 (68%), Gaps = 17/431 (3%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67 I + AREILDSRG+PTVEVD+HT RAAVPSGASTG HEA+ELRDG K R+ GKGV Sbjct: 2 IQKIHAREILDSRGDPTVEVDLHTAKGHFRAAVPSGASTGIHEALELRDGDKKRFLGKGV 61 Query: 68 RRAVENVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 +AVE++NK I P L+ + V Q +ID+++IE+DGTENKS GANAIL VSLAV+ A Sbjct: 62 LKAVEHINKTIGPALIEKKISVVEQEKIDKVVIEMDGTENKSKFGANAILGVSLAVSHAG 121 Query: 126 ANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182 A +PLY++ L G +LPVP NVINGG HAGN L QEFM++P+GA SF +A+ Sbjct: 122 AAEKGVPLYRHIADLAGNTELILPVPAFNVINGGSHAGNKLAMQEFMVLPVGAASFHDAM 181 Query: 183 RWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEI 242 R +E YH LK VI KYGK+A NVGDEGGFAP + + E L++L AI +AGY +++ Sbjct: 182 RVGAEVYHSLKGVIKAKYGKDATNVGDEGGFAPNILDNHEALELLKAAIAQAGYT--DKV 239 Query: 243 ALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPFHEED 295 + +D A+SEF +DG+Y + K T E+L E+Y+ YP+VSIEDPF ++D Sbjct: 240 VIGMDVAASEFCRDGRYDLDFKSPPDPKRLITGEQLGEIYRGFIKDYPVVSIEDPFDQDD 299 Query: 296 WEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAY 355 WE + + +Q+VGDDL V NPKR+ E A N LLL VNQIG++TE++ A Sbjct: 300 WEAWKRFVSHVD--IQVVGDDLTVANPKRIAHAAEQHACNCLLLGVNQIGSVTESIQACK 357 Query: 356 MAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELE 415 +A G+GV+VSHRSGETED IADL V L GQI+ GAP RS+R AKYNQL+RIEE L Sbjct: 358 LAQSHGWGVMVSHRSGETEDTFIADLVVGLCTGQIEQGAPCRSERLAKYNQLMRIEEALG 417 Query: 416 GVAVYAGKNFR 426 A +AG+ FR Sbjct: 418 DKAKFAGRKFR 428 >sp|P75189|ENO_MYCPN ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|2146503|pir||S73562 phosphopyruvate hydratase (EC 4.2.1.11) - Mycoplasma pneumoniae (strain ATCC 29342) >gi|1673903|gb|AAB95884.1| (AE000023) enolase (eno) [Mycoplasma pneumoniae] Length = 456 Score = 421 bits (1072), Expect = e-117 Identities = 233/439 (53%), Positives = 308/439 (70%), Gaps = 23/439 (5%) Query: 7 YEIVAVIAREILDSRGNPTVEVDVHTPIS-MGRAAVPSGASTGTHEAVELRDGG-KRYHG 64 ++I + A ++ DSRG PTV V G A VPSGASTG EA+ELRDG K Y G Sbjct: 10 FKIADLFAYQVFDSRGFPTVACVVKLASGHTGEAMVPSGASTGEKEAIELRDGDPKAYFG 69 Query: 65 KGVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKA 124 KGV +AV+NVN+ IAP+L+G++ Q ID L+I+LDGT NK+ LGANAILAVSLAVAKA Sbjct: 70 KGVSQAVQNVNQTIAPKLIGLNATDQAAIDALMIQLDGTPNKAKLGANAILAVSLAVAKA 129 Query: 125 AANALELPLYQYLG----GVNA--YVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSF 178 AA+A + L++YL G+N ++L VP+ NVINGG HA N++DFQEFMIMP+GANS Sbjct: 130 AASAQKTSLFKYLANQVMGLNKTEFILTVPMLNVINGGAHADNNIDFQEFMIMPLGANSM 189 Query: 179 REAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKP 238 +A++ SET+H L+K++ ++ G N N GDEGGFAP +K E LD++++AI+ AGY+P Sbjct: 190 HQALKMASETFHALQKLLKQR-GLNT-NKGDEGGFAPNLKLAEEALDLMVEAIKAAGYQP 247 Query: 239 GEEIALALDAASSEFYKDG--KY---------IVSGKEY--TREELLELYKELTSTYPIV 285 G +IA+ALD A+SEFY D +Y I+ KE+ T +++ K+LT YPI+ Sbjct: 248 GSDIAIALDVAASEFYDDTTKRYVFKKGIKAKILDEKEWSLTTAQMIAYLKKLTEQYPII 307 Query: 286 SIEDPFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIG 345 SIED E DWEG +T+ LG+ +QIVGDDL+ TNP +KG+ A N++L+K+NQIG Sbjct: 308 SIEDGLSEHDWEGMETLTKTLGQHIQIVGDDLYCTNPAIAEKGVAHKATNSILIKLNQIG 367 Query: 346 TLTEAMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYN 405 TLTE + A +A A + V+SHRSGETED TIADLAVA GQIKTG+ +RS+R AKYN Sbjct: 368 TLTETIKAINIAKDANWSQVISHRSGETEDTTIADLAVAACTGQIKTGSMSRSERIAKYN 427 Query: 406 QLIRIEEELEGVAVYAGKN 424 +L++IE EL A Y G N Sbjct: 428 RLLQIELELGNNAKYLGWN 446 >pir||E81654 enolase TC0876 [imported] - Chlamydia muridarum (strain Nigg) >gi|7190904|gb|AAF39672.1| (AE002354) enolase [Chlamydia muridarum] Length = 424 Score = 419 bits (1066), Expect = e-116 Identities = 228/413 (55%), Positives = 287/413 (69%), Gaps = 6/413 (1%) Query: 14 AREILDSRGNPTVEVDVHTPISM-GRAAVPSGASTGTHEAVELRDGG-KRYHGKGVRRAV 71 AREILDSRG PT+ V V T + G A VPSGASTG EA+ELRD KRY GKGV +AV Sbjct: 11 AREILDSRGYPTLYVKVITNTGIFGEACVPSGASTGIKEALELRDQDPKRYQGKGVLQAV 70 Query: 72 ENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANALEL 131 NV K++ P L G V Q D ++I+ DGT NK LGANAIL VSLA+AKAAA LE Sbjct: 71 ANVEKVLLPALQGFSVFDQITADAIMIDADGTSNKEKLGANAILGVSLALAKAAAATLER 130 Query: 132 PLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVSETYHV 191 PLY+YLGG ++VLP P+ N+INGG+HA N L FQEFMI PI A S EA+R +E +H Sbjct: 131 PLYRYLGGAFSHVLPCPMMNLINGGMHATNGLQFQEFMIRPISAPSLTEAVRMGAEVFHT 190 Query: 192 LKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALALDAASS 251 LKK++ + + + VGDEGGFAP + +E LD+L+ AIE+AG+ PGE+I+LALD A+S Sbjct: 191 LKKILQNR--QLSTGVGDEGGFAPQLASNSEALDLLLAAIEKAGFIPGEDISLALDCAAS 248 Query: 252 EFYKDGKYIVSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMITRELGKKVQ 311 FY GK + + + + EL YPI SIED EED+EG+ +++ LG ++Q Sbjct: 249 SFYNTQDKTYDGK--SAADQVAVLTELCDRYPIDSIEDGLAEEDFEGWKLLSETLGDRIQ 306 Query: 312 IVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYGVVVSHRSG 371 +VGDDLFVTN + +GI G ANA+L+K NQIGTLTE +A +A GY ++SHRSG Sbjct: 307 LVGDDLFVTNSALIAEGIAQGLANAVLIKPNQIGTLTETAEAIRLATTQGYATILSHRSG 366 Query: 372 ETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAGKN 424 ETED TIADLAVA N GQIKTG+ +RS+R AKYN+LI IEEE+ AV+ N Sbjct: 367 ETEDTTIADLAVAFNTGQIKTGSLSRSERIAKYNRLIAIEEEIGPEAVFQDSN 419 >sp|Q9Z7A6|ENO_CHLPN ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|7436889|pir||A72034 enolase - Chlamydophila pneumoniae (strain CWL029) >gi|4377111|gb|AAD18938.1| (AE001661) Enolase [Chlamydophila pneumoniae CWL029] Length = 428 Score = 417 bits (1061), Expect = e-115 Identities = 230/420 (54%), Positives = 294/420 (69%), Gaps = 10/420 (2%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRD-GGKRYHGKG 66 I + AREILDSRG PT+ V V T S+G A VPSGASTG EA+E RD RY GKG Sbjct: 6 IADIQAREILDSRGYPTLHVKVTTSTGSVGEARVPSGASTGKKEALEFRDTDSPRYQGKG 65 Query: 67 VRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAA 126 V +AV+NV +I+ P + G V Q ID L+++ DG+ NK LGANAIL VSLA A AAA Sbjct: 66 VLQAVKNVKEILFPLVKGCSVYEQSLIDSLMMDSDGSPNKETLGANAILGVSLATAHAAA 125 Query: 127 NALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVS 186 L PLY+YLGG A LP P+ N+INGG+HA N L+FQEFMI PIGA+S +EA+ + Sbjct: 126 ATLRRPLYRYLGGCFACSLPCPMMNLINGGMHADNGLEFQEFMIRPIGASSIKEAVNMGA 185 Query: 187 ETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALAL 246 + +H LKK++ E+ + VGDEGGFAP + E L++L+ AIE+AG+ PG++I+LAL Sbjct: 186 DVFHTLKKLLHER--GLSTGVGDEGGFAPNLASNEEALELLLLAIEKAGFTPGKDISLAL 243 Query: 247 DAASSEFY--KDGKYIVSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMITR 304 D A+S FY K G Y G+ Y EE + + L YPI SIED EED++G+ ++T Sbjct: 244 DCAASSFYNVKTGTY--DGRHY--EEQIAILSNLCDRYPIDSIEDGLAEEDYDGWALLTE 299 Query: 305 ELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYGV 364 LG+KVQIVGDDLFVTNP+ + +GI G AN++L+K NQIGTLTE + A +A AGY Sbjct: 300 VLGEKVQIVGDDLFVTNPELILEGISNGLANSVLIKPNQIGTLTETVYAIKLAQMAGYTT 359 Query: 365 VVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAGKN 424 ++SHRSGET D TIADLAVA NAGQIKTG+ +RS+R AKYN+L+ IEEEL A++ N Sbjct: 360 IISHRSGETTDTTIADLAVAFNAGQIKTGSLSRSERVAKYNRLMEIEEELGSEAIFTDSN 419 >gi|6323985 Ymr323wp [Saccharomyces cerevisiae] >gi|1706698|sp|P42222|ERR1_YEAST ENOLASE RELATED PROTEIN 1 >gi|2118301|pir||S69881 phosphopyruvate hydratase (EC 4.2.1.11) YMR323w - yeast (Saccharomyces cerevisiae) >gi|1072413|emb|CAA90841.1| (Z54141) unknown [Saccharomyces cerevisiae] Length = 437 Score = 416 bits (1058), Expect = e-115 Identities = 229/433 (52%), Positives = 289/433 (65%), Gaps = 20/433 (4%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67 I V AR + DSRGNPTVEV++ T + RA VPSGASTG HEAVELRDG K + GKGV Sbjct: 3 ITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGV 62 Query: 68 RRAVENVNKIIAPELVGMD--VRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 +AV NVN II P L+ D V Q+ ID L+I LDGT NKS LGANAIL VSL VA+AA Sbjct: 63 TKAVSNVNSIIGPALIKSDLCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAA 122 Query: 126 ANALELPLYQYLGGV-----NAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFRE 180 A + LY+Y+ + + +V+PVP NV+NGG HAG L QEF I P+GA SF E Sbjct: 123 AAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQSFAE 182 Query: 181 AIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGE 240 A+R SE YH LK + E+YG +A NVGDEGG AP + + LD+++KAI GY+ Sbjct: 183 AMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVKAINICGYEG-- 240 Query: 241 EIALALDAASSEFYKDGKYIVSGKEYTRE--------ELLELYKELTSTYPIVSIEDPFH 292 + + +D+A S FYKDGKY ++ KE + +L E Y L YPI+S+EDP+ Sbjct: 241 RVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLEDPYA 300 Query: 293 EEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMD 352 E+DW + + + VQI+ DDL TN R+ + IE AN LLLK+NQIGTLTE+++ Sbjct: 301 EDDWSSWSAFLKTVN--VQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIE 358 Query: 353 AAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEE 412 AA AF AG+GV++SHRSGETED IADL V L GQIK+GA +RS+R AKYN+L+RIEE Sbjct: 359 AANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEE 418 Query: 413 ELEGVAVYAGKNF 425 EL +YAG F Sbjct: 419 ELGDDCIYAGHRF 431 >pir||G81504 enolase CP1071 [imported] - Chlamydophila pneumoniae (strain AR39) >gi|7189985|gb|AAF38843.1| (AE002264) enolase [Chlamydophila pneumoniae AR39] >gi|8979174|dbj|BAA99008.1| (AP002548) enolase [Chlamydophila pneumoniae J138] Length = 428 Score = 416 bits (1058), Expect = e-115 Identities = 230/420 (54%), Positives = 293/420 (69%), Gaps = 10/420 (2%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRD-GGKRYHGKG 66 I + AREILDSRG PT+ V V T S+G A VPSGASTG EA+E RD RY GKG Sbjct: 6 IADIQAREILDSRGYPTLHVKVTTSTGSVGEARVPSGASTGKKEALEFRDTDSPRYQGKG 65 Query: 67 VRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAA 126 V +AV+NV +I+ P + G V Q ID L+++ DG+ NK LGANAIL VSLA A AAA Sbjct: 66 VLQAVKNVKEILFPLVKGCSVYEQSLIDSLMMDSDGSPNKETLGANAILGVSLATAHAAA 125 Query: 127 NALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVS 186 L PLY+YLGG A LP P+ N+INGG+HA N L FQEFMI PIGA+S +EA+ + Sbjct: 126 ATLRRPLYRYLGGCFACSLPCPMMNLINGGMHADNGLGFQEFMIRPIGASSIKEAVNMGA 185 Query: 187 ETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALAL 246 + +H LKK++ E+ + VGDEGGFAP + E L++L+ AIE+AG+ PG++I+LAL Sbjct: 186 DVFHTLKKLLHER--GLSTGVGDEGGFAPNLASNEEALELLLLAIEKAGFTPGKDISLAL 243 Query: 247 DAASSEFY--KDGKYIVSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMITR 304 D A+S FY K G Y G+ Y EE + + L YPI SIED EED++G+ ++T Sbjct: 244 DCAASSFYNVKTGTY--DGRHY--EEQIAILSNLCDRYPIDSIEDGLAEEDYDGWALLTE 299 Query: 305 ELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYGV 364 LG+KVQIVGDDLFVTNP+ + +GI G AN++L+K NQIGTLTE + A +A AGY Sbjct: 300 VLGEKVQIVGDDLFVTNPELILEGISNGLANSVLIKPNQIGTLTETVYAIKLAQMAGYTT 359 Query: 365 VVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAGKN 424 ++SHRSGET D TIADLAVA NAGQIKTG+ +RS+R AKYN+L+ IEEEL A++ N Sbjct: 360 IISHRSGETTDTTIADLAVAFNAGQIKTGSLSRSERVAKYNRLMEIEEELGSEAIFTDSN 419 >sp|O84591|ENO_CHLTR ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|7436872|pir||D71496 probable enolase - Chlamydia trachomatis (serotype D, strain UW3/Cx) >gi|3329030|gb|AAC68189.1| (AE001329) Enolase [Chlamydia trachomatis] Length = 424 Score = 414 bits (1052), Expect = e-114 Identities = 226/413 (54%), Positives = 285/413 (68%), Gaps = 6/413 (1%) Query: 14 AREILDSRGNPTVEVDVHTPI-SMGRAAVPSGASTGTHEAVELRDGG-KRYHGKGVRRAV 71 AREILDSRG PT+ V V T + G A VPSGASTG EA+ELRD KRY GKGV +A+ Sbjct: 11 AREILDSRGYPTLCVKVITNTGTFGEACVPSGASTGIKEALELRDKDPKRYQGKGVLQAI 70 Query: 72 ENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANALEL 131 NV K++ P L G V Q D ++I+ DGT NK LGANAIL VSLA+AKAAAN L+ Sbjct: 71 SNVEKVLMPALQGFSVFDQITADAIMIDADGTPNKEKLGANAILGVSLALAKAAANTLQR 130 Query: 132 PLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVSETYHV 191 PLY+YLGG ++VLP P+ N+INGG+HA N L FQEFMI PI A S EA+R +E ++ Sbjct: 131 PLYRYLGGSFSHVLPCPMMNLINGGMHATNGLQFQEFMIRPISAPSLTEAVRMGAEVFNA 190 Query: 192 LKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALALDAASS 251 LKK++ + + A VGDEGGFAP + E LD+L+ AIE AG+ P E+I+LALD A+S Sbjct: 191 LKKILQNR--QLATGVGDEGGFAPNLASNAEALDLLLTAIETAGFTPREDISLALDCAAS 248 Query: 252 EFYKDGKYIVSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMITRELGKKVQ 311 FY GK Y + + + EL YPI SIED EED+EG+ +++ LG +VQ Sbjct: 249 SFYNTQDKTYDGKSYADQ--VGILAELCEHYPIDSIEDGLAEEDFEGWKLLSETLGDRVQ 306 Query: 312 IVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYGVVVSHRSG 371 +VGDDLFVTN + +GI G ANA+L+K NQIGTLTE +A +A GY ++SHRSG Sbjct: 307 LVGDDLFVTNSALIAEGIAQGLANAVLIKPNQIGTLTETAEAIRLATIQGYATILSHRSG 366 Query: 372 ETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAGKN 424 ETED TIADLAVA N GQIKTG+ +RS+R AKYN+L+ IEEE+ A++ N Sbjct: 367 ETEDTTIADLAVAFNTGQIKTGSLSRSERIAKYNRLMAIEEEMGPEALFQDSN 419 >gi|6324969 enolase homolog; Err1p [Saccharomyces cerevisiae] >gi|6324974|ref|NP_015042.1| Similar to enolase; Err2p [Saccharomyces cerevisiae] >gi|2118299|pir||S67305 phosphopyruvate hydratase (EC 4.2.1.11) ERR1 - yeast (Saccharomyces cerevisiae) >gi|1370578|emb|CAA98018.1| (Z73637) ORF YPL281c [Saccharomyces cerevisiae] >gi|1420845|emb|CAA99725.1| (Z75301) ORF YOR393w [Saccharomyces cerevisiae] Length = 437 Score = 413 bits (1050), Expect = e-114 Identities = 227/433 (52%), Positives = 289/433 (66%), Gaps = 20/433 (4%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67 I V AR + DSRGNPTVEV++ T + RA VPSGASTG HEAVELRDG K + GKGV Sbjct: 3 ITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGV 62 Query: 68 RRAVENVNKIIAPELVGMD--VRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 +AV NVN II P L+ + V Q+ ID L+I LDGT NKS LGANAIL VSL VA+AA Sbjct: 63 TKAVSNVNSIIGPALIKSELCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAA 122 Query: 126 ANALELPLYQYLGGV-----NAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFRE 180 A + LY+Y+ + + +V+PVP NV+NGG HAG L QEF I P+GA SF E Sbjct: 123 AAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQSFAE 182 Query: 181 AIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGE 240 A+R SE YH LK + E+YG +A NVGDEGG AP + + LD++++AI GY+ Sbjct: 183 AMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVEAINICGYEG-- 240 Query: 241 EIALALDAASSEFYKDGKYIVSGKEYTRE--------ELLELYKELTSTYPIVSIEDPFH 292 + + +D+A S FYKDGKY ++ KE + +L E Y L YPI+S+EDP+ Sbjct: 241 RVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLEDPYA 300 Query: 293 EEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMD 352 E+DW + + + VQI+ DDL TN R+ + IE AN LLLK+NQIGTLTE+++ Sbjct: 301 EDDWSSWSAFLKTVN--VQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIE 358 Query: 353 AAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEE 412 AA AF AG+GV++SHRSGETED IADL V L GQIK+GA +RS+R AKYN+L+RIEE Sbjct: 359 AANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEE 418 Query: 413 ELEGVAVYAGKNF 425 EL +YAG F Sbjct: 419 ELGDDCIYAGHRF 431 >sp|P57492|ENO_BUCAI ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|10039081|dbj|BAB13115.1| (AP001119) enolase [Buchnera sp. APS] Length = 434 Score = 411 bits (1045), Expect = e-114 Identities = 220/417 (52%), Positives = 299/417 (70%), Gaps = 12/417 (2%) Query: 8 EIVAVIAREILDSRGNPTVEVDVHTPIS-MGRAAVPSGASTGTHEAVELRDGGK-RYHGK 65 +I +IAREI+DSRGNPTVE +VH +G A+ PSGASTG+ EA+ELRD K R+ GK Sbjct: 3 KITKIIAREIIDSRGNPTVESEVHLEGGFVGLASSPSGASTGSLEALELRDENKDRFMGK 62 Query: 66 GVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 GV +AV +N+ I+ L + R Q +ID ++I+LDGT NKS LGANAIL+VSLAVAKAA Sbjct: 63 GVEKAVSLINEKISIALKNKNARNQSDIDHIMIDLDGTINKSKLGANAILSVSLAVAKAA 122 Query: 126 ANALELPLYQYLGGVN----AYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREA 181 A + +PLY ++ +N + +P+P+ N+INGG HA N++D QEFMI PI A + +E+ Sbjct: 123 AASKRMPLYAHIAEINETPGVFSMPLPMINIINGGKHANNNIDIQEFMIQPISAKTVKES 182 Query: 182 IRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEE 241 IR E +H L +++ EK + VGDEGG+AP +K E L+++ AI++ YK G++ Sbjct: 183 IRIGCEIFHALGELLKEK--GMSTTVGDEGGYAPNLKSNEEALNIIQDAIQKTKYKLGQD 240 Query: 242 IALALDAASSEFYK--DGKYIVSGKE--YTREELLELYKELTSTYPIVSIEDPFHEEDWE 297 I LA+D A+SE Y + KY + G+ ++ +E ++L+ YPIVSIED E DWE Sbjct: 241 IRLAIDCAASELYNKNEKKYNLKGENISFSSKEFTHYLEKLSQKYPIVSIEDGQDESDWE 300 Query: 298 GFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMA 357 GF+ T LG K+Q+VGDDLFVTN LKKGI+ G AN++L+K+NQIGTLTE ++A A Sbjct: 301 GFLYQTHVLGNKIQLVGDDLFVTNKNILKKGIKKGIANSILIKLNQIGTLTETLEAIKTA 360 Query: 358 FRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEEL 414 +A YGV++SHRSGETEDA+IADL+V ++GQIKTG+ +RSDR +KYNQLIRIEE L Sbjct: 361 KQANYGVIISHRSGETEDASIADLSVGTSSGQIKTGSMSRSDRTSKYNQLIRIEENL 417 >dbj|BAA88483.1| (AB025330) enolase-2 [Lampetra reissneri] Length = 395 Score = 408 bits (1038), Expect = e-113 Identities = 223/394 (56%), Positives = 280/394 (70%), Gaps = 17/394 (4%) Query: 46 STGTHEAVELRDGGK-RYHGKGVRRAVENVNKIIAPELVGMD--VRWQREIDRLLIELDG 102 STG +EA+ELRDG K RY GKGV +AV ++NK IAP L+ + V Q +ID ++ELDG Sbjct: 1 STGIYEALELRDGDKSRYLGKGVLKAVNHINKEIAPALIAKNFSVVDQEKIDNFMLELDG 60 Query: 103 TENKSNLGANAILAVSLAVAKAAANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHA 159 TENKS GANAIL VSLAV KAAA +PLY++ L G +LPVP NVINGG HA Sbjct: 61 TENKSKFGANAILGVSLAVCKAAAAEKGVPLYRHIADLAGHKEVILPVPAFNVINGGSHA 120 Query: 160 GNDLDFQEFMIMPIGANSFREAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKE 219 GN L QEFMI+P+GA+SF EA+R +E YH LK VI EKYGK+A NVGDEGGFAP + E Sbjct: 121 GNKLAMQEFMILPVGASSFHEALRIGAEVYHNLKGVIKEKYGKDATNVGDEGGFAPNILE 180 Query: 220 VTEPLDVLIKAIEEAGYKPGEEIALALDAASSEFYKDGKYIVSGKE-------YTREELL 272 E L++L AI +AGY ++I + +D A+SEFY+ G Y + K T ++L Sbjct: 181 NKEALELLKTAINKAGYS--DKIVIGMDVAASEFYRKGMYDLDFKSPDDPKRYITPDKLA 238 Query: 273 ELYKELTSTYPIVSIEDPFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMG 332 ELY+ T YP+VSIEDPF ++DWE + IT K+QIVGDDL VTNPKR++K +++ Sbjct: 239 ELYQGFTKDYPVVSIEDPFDQDDWEAWTKITANT--KIQIVGDDLTVTNPKRIQKAVDVK 296 Query: 333 AANALLLKVNQIGTLTEAMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKT 392 A N LLLKVNQIG++TE++ A +A G+GV+VSHRSGETED IADL V L GQIKT Sbjct: 297 ACNCLLLKVNQIGSVTESIKACKLAQNNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKT 356 Query: 393 GAPARSDRNAKYNQLIRIEEELEGVAVYAGKNFR 426 GAP RS+R +KYNQ++RIEEEL A +AG +FR Sbjct: 357 GAPCRSERLSKYNQIMRIEEELGDKAKFAGHSFR 390 >gb|AAB87891.1| (AF025806) enolase [Drosophila subobscura] Length = 413 Score = 406 bits (1033), Expect = e-112 Identities = 221/415 (53%), Positives = 282/415 (67%), Gaps = 18/415 (4%) Query: 27 EVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRAVENVNKIIAPELV-- 83 EVD+ T + RAAVPSGASTG HEA+ELRD K YHGK V +AV +VN + PE++ Sbjct: 1 EVDLTTEHGLFRAAVPSGASTGVHEALELRDNDKANYHGKSVLKAVAHVNDTLGPEVIKA 60 Query: 84 GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANALELPLYQY---LGGV 140 +DV Q +D +I+LDGTENKS GANAIL +SLAVAKA A +PLY++ L G Sbjct: 61 NLDVVDQAAVDNFMIKLDGTENKSKFGANAILGISLAVAKAGAAKKNVPLYKHIADLAGN 120 Query: 141 NAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVSETYHVLKKVIAEKY 200 +LPVP NVINGG HAGN L QEFMI+P GA +F EA++ SE YH LK VI K+ Sbjct: 121 KEIILPVPAFNVINGGSHAGNKLAMQEFMILPTGATTFTEAMKMGSEVYHHLKNVIKAKF 180 Query: 201 GKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALALDAASSEFYKDGKYI 260 G +A VGDEGGFAP ++ E L ++ AI +AGY +I + +D A+SEF+KDG Y Sbjct: 181 GLDATAVGDEGGFAPNIQSNKEALVLITDAIAKAGYTG--KIEIGMDVAASEFFKDGLYD 238 Query: 261 VSGKE--------YTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMITRELGKKVQI 312 + K T ++L LY+E +PI SIEDPF ++ W+ + +T K+QI Sbjct: 239 LDFKNPASDKAQWLTPDKLANLYQEFIKEFPITSIEDPFDQDHWDAWTNLTSNT--KIQI 296 Query: 313 VGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYGVVVSHRSGE 372 VGDDL VTNPKR+ +E GA N LLLKVNQIGT+TE++ A +A + G+G +VSHRSGE Sbjct: 297 VGDDLTVTNPKRIATAVEKGACNCLLLKVNQIGTVTESIAAHLLAKKNGWGTMVSHRSGE 356 Query: 373 TEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAGKNFRK 427 TED+ I DL V L+ GQIKTGAP RS+R AKYNQ++RIEEE+ +AGK+FRK Sbjct: 357 TEDSFIGDLVVGLSTGQIKTGAPCRSERLAKYNQILRIEEEIGSGVKFAGKSFRK 411 >sp|P47647|ENO_MYCGE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|1361755|pir||A64245 phosphopyruvate hydratase (EC 4.2.1.11) - Mycoplasma genitalium >gi|3845000|gb|AAC71635.1| (U39723) enolase (eno) [Mycoplasma genitalium] Length = 458 Score = 403 bits (1024), Expect = e-111 Identities = 217/438 (49%), Positives = 297/438 (67%), Gaps = 23/438 (5%) Query: 8 EIVAVIAREILDSRGNPTVEVDVHTPIS-MGRAAVPSGASTGTHEAVELRDGG-KRYHGK 65 +I + A ++ DSRG PTV V +G A VPSGASTG EA+ELRD K Y GK Sbjct: 11 KITDIFAYQVFDSRGVPTVACVVKLASGHVGEAMVPSGASTGEKEAIELRDNDPKNYFGK 70 Query: 66 GVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 GV AV+NVNK+IAP+L+G++ Q +D+ +I+LD T NK+ LGANAIL+VSLAV+KAA Sbjct: 71 GVNEAVDNVNKVIAPKLIGLNAFDQLTVDQAMIKLDNTPNKAKLGANAILSVSLAVSKAA 130 Query: 126 ANALELPLYQYLG----GVNA--YVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFR 179 A A L+QY+ G+N +VLPVP+ NVINGG HA N +DFQEFMIMP+GA Sbjct: 131 AKAQNSSLFQYISNKLIGLNTTNFVLPVPMLNVINGGAHADNYIDFQEFMIMPLGAKKMH 190 Query: 180 EAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPG 239 EA++ SET+H L+ ++ +K G N N GDEGGFAP +K + LD++++AI+ AGYKP Sbjct: 191 EALKMASETFHALQNLL-KKRGLNT-NKGDEGGFAPNLKLAEDALDIMVEAIKLAGYKPW 248 Query: 240 EEIALALDAASSEFYKDGKY-----------IVSGKEY--TREELLELYKELTSTYPIVS 286 ++IA+A+D A+SEFY + K I++ K++ T +E++ ++LT YPI+S Sbjct: 249 DDIAIAIDVAASEFYDEDKKLYVFKKGIKANILNAKDWSLTSKEMIAYLEKLTKKYPIIS 308 Query: 287 IEDPFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGT 346 IED E DWEG +T+ +G +QIVGDD + TN + KKG+ N++L+K+NQIG+ Sbjct: 309 IEDGLSENDWEGMNQLTKTIGSHIQIVGDDTYCTNAELAKKGVAQNTTNSILIKLNQIGS 368 Query: 347 LTEAMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQ 406 ++E + +A +A + V+SHRSGETED TIADLAVA GQIKTG+ +RS+R AKYN+ Sbjct: 369 ISETIQTIEVAKKANWSQVISHRSGETEDTTIADLAVAAQTGQIKTGSMSRSERIAKYNR 428 Query: 407 LIRIEEELEGVAVYAGKN 424 L+ IE EL Y G N Sbjct: 429 LLYIEIELGDKGKYLGWN 446 >gb|AAB87890.1| (AF025805) enolase [Drosophila pseudoobscura] Length = 413 Score = 403 bits (1024), Expect = e-111 Identities = 219/415 (52%), Positives = 280/415 (66%), Gaps = 18/415 (4%) Query: 27 EVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGVRRAVENVNKIIAPELV-- 83 EVD+ T + RAAVPSGASTG HEA+ELRD K YHGK V +AV +VN + PE++ Sbjct: 1 EVDLTTENGLFRAAVPSGASTGVHEALELRDNDKANYHGKSVLKAVAHVNDTLGPEVIKA 60 Query: 84 GMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAANALELPLYQY---LGGV 140 +DV Q +D +I+LDGTENKS GANAIL +SLAVAKA A +PLY++ L G Sbjct: 61 NLDVVDQAAVDNFMIKLDGTENKSKFGANAILGISLAVAKAGAAKKNVPLYKHIADLAGN 120 Query: 141 NAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRWVSETYHVLKKVIAEKY 200 +LPVP NVINGG HAGN L QEFMI+P GA +F EA++ SE YH LK VI K+ Sbjct: 121 KEIILPVPAFNVINGGSHAGNKLAMQEFMILPTGATTFTEAMKMGSEVYHHLKNVIKAKF 180 Query: 201 GKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIALALDAASSEFYKDGKYI 260 G +A VGDEGGFAP ++ E L ++ AI +AGY +I + +D A+SEF+KDG Y Sbjct: 181 GLDATAVGDEGGFAPNIQSNKEALVLITDAIAKAGYTG--KIEIGMDVAASEFFKDGLYD 238 Query: 261 VSGKE--------YTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMITRELGKKVQI 312 + K + ++ LY+E +PI SIEDPF ++ W+ + +T K+QI Sbjct: 239 LDFKNPASDKAQWLSPDKXANLYQEFIKEFPITSIEDPFDQDHWDAWTNLT--CNTKIQI 296 Query: 313 VGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYGVVVSHRSGE 372 VGDDL VTNPKR+ +E GA N LLLKVNQIGT+TE++ A +A + G+G +VSHRSGE Sbjct: 297 VGDDLTVTNPKRIATAVEKGACNCLLLKVNQIGTVTESIAAHLLAKKNGWGTMVSHRSGE 356 Query: 373 TEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAGKNFRK 427 TED+ DL V L+ GQIKTGAP RS+R AKYNQ++RIEEE+ +AGKNFRK Sbjct: 357 TEDSFXGDLVVGLSTGQIKTGAPCRSERLAKYNQILRIEEEIGSGVKFAGKNFRK 411 >dbj|BAA88479.1| (AB025326) enolase [Eptatretus burgeri] Length = 395 Score = 403 bits (1024), Expect = e-111 Identities = 216/394 (54%), Positives = 280/394 (70%), Gaps = 17/394 (4%) Query: 46 STGTHEAVELRDGGK-RYHGKGVRRAVENVNKIIAPELVG--MDVRWQREIDRLLIELDG 102 STG +EA+ELRDG K RY GKGV +AV ++N IAP+L+ +V+ Q ID+ +++LDG Sbjct: 1 STGIYEALELRDGDKSRYLGKGVLKAVNHINATIAPKLIAKNFNVKDQTAIDKFMLDLDG 60 Query: 103 TENKSNLGANAILAVSLAVAKAAANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHA 159 TENKS GANAIL VSLAV KAAA +PLY++ L G +LPVP NVINGG HA Sbjct: 61 TENKSQFGANAILGVSLAVCKAAAAEKGVPLYRHIADLAGHKDVILPVPAFNVINGGSHA 120 Query: 160 GNDLDFQEFMIMPIGANSFREAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKE 219 GN L QEFMI+P+GA +F +A+R +E YH LK VI +KYGK+A NVGDEGGFAP + + Sbjct: 121 GNKLAMQEFMILPVGAANFHDAMRIGAEVYHNLKSVIKDKYGKDATNVGDEGGFAPNILD 180 Query: 220 VTEPLDVLIKAIEEAGYKPGEEIALALDAASSEFYKDGKYIVSGKE-------YTREELL 272 E L++L AI +AGY ++I + +D A+SEFY+DGKY + K + ++L Sbjct: 181 NQEALELLKHAINKAGYT--DKIVIGMDVAASEFYRDGKYDLDFKSPDDPSRHISPDKLA 238 Query: 273 ELYKELTSTYPIVSIEDPFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMG 332 +LY YP+VSIEDPF ++ WE + T +Q+VGDDL VTNPKR++KG+++ Sbjct: 239 DLYHGFIKDYPVVSIEDPFDQDHWEAWTKFTASTD--IQVVGDDLTVTNPKRIQKGVDIK 296 Query: 333 AANALLLKVNQIGTLTEAMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKT 392 A N LLLKVNQIG++TE++ A +A G+GV+VSHRSGETED+ IADL V L GQIKT Sbjct: 297 ACNCLLLKVNQIGSVTESIQACKLAQNNGWGVMVSHRSGETEDSFIADLVVGLCTGQIKT 356 Query: 393 GAPARSDRNAKYNQLIRIEEELEGVAVYAGKNFR 426 GAP RS+R AKYNQ++RIEEEL A +AGKNFR Sbjct: 357 GAPCRSERLAKYNQMMRIEEELGSNAKFAGKNFR 390 >gb|AAC95183.1| (AC004561) putative enolase (2-phospho-D-glycerate hydroylase) [Arabidopsis thaliana] Length = 475 Score = 400 bits (1017), Expect = e-110 Identities = 220/430 (51%), Positives = 299/430 (69%), Gaps = 16/430 (3%) Query: 9 IVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGK-RYHGKGV 67 I V AR+ILDSRG PTVEVD+HT + RA+VPSG S+GT+EA+ELRDG K Y G V Sbjct: 47 ITKVKARQILDSRGIPTVEVDLHTNKGVFRASVPSGDSSGTYEAIELRDGDKGMYLGNSV 106 Query: 68 RRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAAN 127 +AV+N+N+ I+ L+GMD + Q +ID+ +I+LD TE KS LGANAILAVS+A KA A Sbjct: 107 AKAVKNINEKISEALIGMDPKLQGQIDQAMIDLDKTEKKSELGANAILAVSIAACKAGAA 166 Query: 128 ALELPLYQYLGGVNA---YVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIRW 184 E+PL ++L ++ VLPVP V++GG HA N QE MI+PIGA+ F EA++W Sbjct: 167 EKEVPLCKHLSDLSGRANMVLPVPAFTVLSGGKHASNTFAIQEIMILPIGASRFEEALQW 226 Query: 185 VSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIAL 244 SETYH LK VI+EK G NVG++GG AP + + E L+++ +AI GY ++I + Sbjct: 227 GSETYHHLKAVISEKNGGLGCNVGEDGGLAPDISSLKEGLELVKEAINRTGYN--DKIKI 284 Query: 245 ALDAASSEFYKDGKYIV-------SGKEY-TREELLELYKELTSTYPIVSIEDPFHEEDW 296 A+D A++ F KY + SG+ + + E+++++YKE+ + YPIVSIEDPF +EDW Sbjct: 285 AIDIAATNFCLGTKYDLDIKSPNKSGQNFKSAEDMIDMYKEICNDYPIVSIEDPFDKEDW 344 Query: 297 EGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYM 356 E + LG Q+VGDDL ++N KR+++ I+ + NALLLKVNQIGT+TEA++ M Sbjct: 345 EHTKYFS-SLGI-CQVVGDDLLMSNSKRVERAIQESSCNALLLKVNQIGTVTEAIEVVKM 402 Query: 357 AFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEG 416 A A +GVV SHR GETED+ I+DL+V L G IK GAP R +R KYNQL+RIEEEL Sbjct: 403 ARDAQWGVVTSHRCGETEDSFISDLSVGLATGVIKAGAPCRGERTMKYNQLLRIEEELGD 462 Query: 417 VAVYAGKNFR 426 AVYAG++++ Sbjct: 463 QAVYAGEDWK 472 >dbj|BAA88482.1| (AB025329) enolase-1 [Lampetra reissneri] Length = 394 Score = 400 bits (1016), Expect = e-110 Identities = 217/394 (55%), Positives = 276/394 (69%), Gaps = 17/394 (4%) Query: 46 STGTHEAVELRDGGK-RYHGKGVRRAVENVNKIIAPELVGMD--VRWQREIDRLLIELDG 102 STG +EA+ELRD K RY GKGV +AV ++N IAP L+ V Q ID+ +++LDG Sbjct: 1 STGIYEALELRDDDKGRYLGKGVLQAVSHINDTIAPALLSQSFSVVEQEAIDQFMLDLDG 60 Query: 103 TENKSNLGANAILAVSLAVAKAAANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHA 159 TENKS GANA+L VSLAV KA A +PLY++ L G + +LPVP NVINGG HA Sbjct: 61 TENKSKFGANAVLGVSLAVCKAGAGEKGVPLYRHIADLAGNSEVILPVPAFNVINGGSHA 120 Query: 160 GNDLDFQEFMIMPIGANSFREAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKE 219 GN L QEFMI+P+GA S EA+R +E YH LK VI +KYG++A NVGDEGGFAP + E Sbjct: 121 GNKLAMQEFMILPVGAESLSEALRMGAEVYHSLKAVIKKKYGQDATNVGDEGGFAPNILE 180 Query: 220 VTEPLDVLIKAIEEAGYKPGEEIALALDAASSEFYKDGKYIVSGKE-------YTREELL 272 E LD+L +AI +AGY ++I + +D A+SEFY+DGKY + K + +EL Sbjct: 181 NMEALDLLTQAIGKAGYT--DKIVIGMDVAASEFYRDGKYDLDFKSPADPDRYISADELA 238 Query: 273 ELYKELTSTYPIVSIEDPFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMG 332 +LY+ S YP+VSIEDPF ++DWE + T G +QIVGDDL VTNP R++ +++ Sbjct: 239 DLYRTFISDYPVVSIEDPFDQDDWEAWSNFTANAG--IQIVGDDLTVTNPARIQTAVDVK 296 Query: 333 AANALLLKVNQIGTLTEAMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKT 392 A N LLLKVNQIG++TE++ A +A G+GV+VSHRSGETED IADL V L GQIKT Sbjct: 297 ACNCLLLKVNQIGSVTESIKACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKT 356 Query: 393 GAPARSDRNAKYNQLIRIEEELEGVAVYAGKNFR 426 GAP RS+R AKYNQL+RIEEEL A +AG+NFR Sbjct: 357 GAPCRSERLAKYNQLMRIEEELGKKAQFAGRNFR 390 >sp|P31683|ENO_CHLRE ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|99392|pir||S24996 phosphopyruvate hydratase (EC 4.2.1.11) - Chlamydomonas reinhardtii >gi|18143|emb|CAA47043.1| (X66412) enolase [Chlamydomonas reinhardtii] Length = 372 Score = 393 bits (998), Expect = e-108 Identities = 211/374 (56%), Positives = 269/374 (71%), Gaps = 16/374 (4%) Query: 67 VRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAAA 126 V +AVEN+N IIAP L GMD Q EID+ + +LDGT+NK LGANAILAVS+AV KA A Sbjct: 1 VTKAVENINAIIAPALKGMDPVKQAEIDQKMKDLDGTDNKGKLGANAILAVSMAVCKAGA 60 Query: 127 NALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAIR 183 +PLY++ L G + +LPVP N+INGG HAGN L QEFMI+P+GA+SF EA+R Sbjct: 61 AEKGVPLYKHIADLAGNSKLILPVPSFNIINGGSHAGNALAMQEFMILPVGASSFSEAMR 120 Query: 184 WVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEEIA 243 E YH LK +I KYG++A NVGDEGGFAP + E L+++ +AIE+AGY ++ Sbjct: 121 MGCEVYHALKGLIKAKYGQDACNVGDEGGFAPNIGSNDEGLNLVNEAIEKAGYTG--KVK 178 Query: 244 LALDAASSEFY-KDGKYIVSGKEY--------TREELLELYKELTSTYPIVSIEDPFHEE 294 + +D ASSEFY +DG Y + K T+E++LELY E YP++SIEDPF ++ Sbjct: 179 IGMDVASSEFYTEDGMYDLDFKNQPNDGSQKKTKEQMLELYNEFCKKYPVISIEDPFEQD 238 Query: 295 DWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAA 354 DWE +T E Q+VGDD+ VTNP R+KK I+ A NALLLKVNQIGT+TE+++A Sbjct: 239 DWEPCAKLTTE--NICQVVGDDILVTNPVRVKKAIDAKAVNALLLKVNQIGTITESIEAV 296 Query: 355 YMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEEL 414 MA AG+GV+ SHRSGETED+ IADLAV L +GQIKTGAP RS+RNAKYNQL+RIEEEL Sbjct: 297 RMAKEAGWGVMTSHRSGETEDSFIADLAVGLASGQIKTGAPCRSERNAKYNQLLRIEEEL 356 Query: 415 EGVAVYAGKNFRKV 428 AVYAG+++R + Sbjct: 357 GENAVYAGESWRHI 370 >gb|AAA49217.1| (M55143) alpha-enolase/tau-crystallin [Anas platyrhynchos] Length = 377 Score = 388 bits (986), Expect = e-107 Identities = 208/375 (55%), Positives = 265/375 (70%), Gaps = 16/375 (4%) Query: 64 GKGVRRAVENVNKIIAPELVGMDVRW--QREIDRLLIELDGTENKSNLGANAILAVSLAV 121 GKGV +AVE++NK IAP L+ +V Q +ID+L++++DG+ENKS GANAIL VSLAV Sbjct: 2 GKGVSKAVEHINKTIAPALISKNVNVVEQDKIDKLMLDMDGSENKSKFGANAILGVSLAV 61 Query: 122 AKAAANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSF 178 KA A +PLY++ L G +LPVP NVINGG HAGN L QEFMI P GA+SF Sbjct: 62 CKAGAAEKGVPLYRHIADLAGNPEVILPVPAFNVINGGSHAGNKLAMQEFMIPPCGADSF 121 Query: 179 REAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKP 238 +EA+R +E YH LK VI EKYGK+A NVGDEGGFAP + E E L++L AI +AGY Sbjct: 122 KEAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKTAIGKAGYS- 180 Query: 239 GEEIALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPF 291 +++ + +D A+SEFY+DGKY + K + ++L +LYK YP+VSIEDPF Sbjct: 181 -DKVVIGMDVAASEFYRDGKYDLDFKSPDDPSRYISPDQLADLYKGFVKNYPVVSIEDPF 239 Query: 292 HEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAM 351 ++DW + T +G +Q+VGDDL VTNPKR+ K +E A N LLLKVNQIG++TE++ Sbjct: 240 DQDDWGAWKKFTGSVG--IQVVGDDLTVTNPKRIAKAVEEKACNCLLLKVNQIGSVTESL 297 Query: 352 DAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIE 411 A +A G+GV+VSHRSGETED IADL V L GQIKTGAP RS+R AKYNQL+RIE Sbjct: 298 QACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIE 357 Query: 412 EELEGVAVYAGKNFR 426 EEL A +AG+NFR Sbjct: 358 EELGSKARFAGRNFR 372 >gb|AAA37554.1| (M20745) muscle-specific enolase beta subunit (EC 4.2.1.11) [Mus musculus] Length = 376 Score = 374 bits (951), Expect = e-103 Identities = 205/375 (54%), Positives = 259/375 (68%), Gaps = 16/375 (4%) Query: 64 GKGVRRAVENVNKIIAPELVG--MDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAV 121 GKGV +AVE++NK + P L+ + V Q ++D+ +IELDGTENKS GANAIL VSLAV Sbjct: 1 GKGVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAV 60 Query: 122 AKAAANALELPLYQY---LGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSF 178 KA A +PLY++ L G VLPVP NVINGG HAGN L QEFMI+P+GA+SF Sbjct: 61 CKAGAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSF 120 Query: 179 REAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKP 238 +EA+R +E YH LK VI KYGK+A NVGDEGGFAP + E E L++L AI+ Y Sbjct: 121 KEAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQANAYP- 179 Query: 239 GEEIALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKELTSTYPIVSIEDPF 291 +++ + +D A+SEFY++GKY + K + E+L ELYK YP+VSIEDPF Sbjct: 180 -DKVVIGMDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGELYKNFIQNYPVVSIEDPF 238 Query: 292 HEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAM 351 ++DW + G +QIVGDDL VTNPKR+ + +E A N LLLKVNQIG++TE++ Sbjct: 239 DQDDWATWTSFLS--GVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESI 296 Query: 352 DAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIE 411 A +A G+GV+VSHRSGETED IADL V L GQIKTGAP RS+R AKYNQL+RIE Sbjct: 297 QACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIE 356 Query: 412 EELEGVAVYAGKNFR 426 E L AV+AG+ FR Sbjct: 357 EALGDKAVFAGRKFR 371 >pir||H82922 enolase UU184 [imported] - Ureaplasma urealyticum >gi|6899148|gb|AAF30591.1|AE002118_1 (AE002118) enolase [Ureaplasma urealyticum] Length = 440 Score = 369 bits (936), Expect = e-101 Identities = 206/441 (46%), Positives = 280/441 (62%), Gaps = 25/441 (5%) Query: 8 EIVAVIAREILDSRGNPTVEVDVHTPISMGRAA-VPSGASTGTHEAVELRDGGKRYH-GK 65 +I+ ++A +ILDSRG PTV V + A VPSGASTG EA+ELRDG Y K Sbjct: 2 KIINLLAYQILDSRGQPTVAVKLFLENDQSVIAMVPSGASTGAKEALELRDGDVNYFFNK 61 Query: 66 GVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 V+ A++N+N II P L+ +V E+D LLI LDGTENKS LGANA+L VS+A+ KA Sbjct: 62 SVKLAIQNINNIIRPHLINKNVLNFFELDNLLINLDGTENKSKLGANALLGVSIAIVKAG 121 Query: 126 ANALELPLYQYLG-------GVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSF 178 A A PLYQY+ VN Y P+PL N INGG HA NDLD QEFMI+P+ A SF Sbjct: 122 AIAASKPLYQYIKEDLMHNYDVNYYA-PIPLMNFINGGAHADNDLDIQEFMIVPLNAISF 180 Query: 179 REAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKP 238 +AI+ SE +H L K++ K + GDEGGFAP +K L++L+ AI++A Y P Sbjct: 181 SQAIQIGSEIFHQLDKLL--KSNHLSTTKGDEGGFAPMLKNNYVTLELLVHAIKKAHYLP 238 Query: 239 GEE--IALALDAASSEFYKDGKYI----------VSGKEYTREELLELYKELTSTYPIVS 286 + + LALD A+SE Y++GKY + ++ +E ++ + +L S +PI+S Sbjct: 239 SKTQGVCLALDVAASELYENGKYFFKKSSSHNITLEQTSFSSDEWIKYWSKLVSMFPIIS 298 Query: 287 IEDPFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGT 346 IED F E DW F + + +Q+VGDDL+ TN K L+KGI+ A NA+L+K NQIGT Sbjct: 299 IEDCFEENDWNSFALFLKN-NPHIQVVGDDLYCTNLKYLQKGIDFKATNAILIKPNQIGT 357 Query: 347 LTEAMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQ 406 ++E +D A + ++SHRSGETED IADLA+ + AGQIKTG+ +RS+R AKYN+ Sbjct: 358 ISETLDVIKFAQKNNINTIISHRSGETEDTFIADLAIGVGAGQIKTGSLSRSERIAKYNR 417 Query: 407 LIRIEEELEGVAVYAGKNFRK 427 ++ IE+EL+ +Y F K Sbjct: 418 ILEIEQELKDKLIYEPSKFFK 438 >gi|7657062 enolase alpha, lung-specific [Homo sapiens] >gi|729422|sp|Q05524|ENOL_HUMAN ALPHA ENOLASE, LUNG SPECIFIC (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) (NON-NEURAL ENOLASE) (NNE) (PHOSPHOPYRUVATE HYDRATASE) >gi|105931|pir||S22071 phosphopyruvate hydratase (EC 4.2.1.11) - human >gi|2135922|pir||I37360 phosphopyruvate hydratase (EC 4.2.1.11), lung - human >gi|31179|emb|CAA47179.1| (X66610) enolase [Homo sapiens] Length = 458 Score = 363 bits (923), Expect = 2e-99 Identities = 229/447 (51%), Positives = 296/447 (65%), Gaps = 36/447 (8%) Query: 14 AREILDSRGNPTVEVDVHTPIS--MGRAAVPSGASTGTHEAV-ELRDGGKRYH--GKGVR 68 AR+I +SRGNPTVEVD++T GRAAVPSGASTG +EA+ ELRD K + GKGV Sbjct: 9 ARDIFESRGNPTVEVDLYTNKGGLFGRAAVPSGASTGIYEALLELRDNDKTRYMGGKGVS 68 Query: 69 RAVENV-NKIIAPELVGMDVRW--QREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 +AVE++ NK IAP L+ +V Q +ID L++++DG+ENKS GANAIL VSLAV A Sbjct: 69 KAVEHIINKTIAPALISKNVNVVEQDKIDNLMLDMDGSENKSKFGANAILGVSLAVCSNA 128 Query: 126 ANALE--LPLYQYL----GGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFR 179 E +PLY+++ G +LPVP NVINGG HAGN L QEFMI P GA+ F Sbjct: 129 GATAEKGVPLYRHIADLAGNNPEVILPVPAFNVINGGSHAGNKLAMQEFMIPPCGADRFN 188 Query: 180 EAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPG 239 +AIR +E YH LK VI EKYGK+A NVGDEGGFAP + E E L++L AI +AGY Sbjct: 189 DAIRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKTAIGKAGY--S 246 Query: 240 EEIALALDAASSEFYKDGKYIVS-------GKEYTREELLELYK-----ELTSTYPI-VS 286 +++ + +D A+SEFY+DGKY + + + ++L +LYK YP+ VS Sbjct: 247 DKVVIGMDVAASEFYRDGKYDLDFNSPDDPSRYISPDQLADLYKGFVLGHAVKNYPVGVS 306 Query: 287 IED-PFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPK-RLKKGI-EMGAANA-LLLKVN 342 IED PF ++DW + + +Q+VGDDL VT P+ R+ K + E+ A N LLLKVN Sbjct: 307 IEDPPFDQDDWGAWKKLFTGSLVGIQVVGDDLTVTKPEARIAKAVEEVKACNCLLLLKVN 366 Query: 343 QIGTLTEAMDAAYMAFRAGYGVV-VSHR-SGETEDATIADLAVALNAGQIKTGAPARSDR 400 QIG++TE++ A +A G+GV+ VSHR SGETED +ADL V L GQIKTG RS+R Sbjct: 367 QIGSVTESLQACKLAQSNGWGVMPVSHRLSGETEDTFMADLVVGLCTGQIKTGPTCRSER 426 Query: 401 NAKYNQLIRIEE-ELEGVAVYAGKNFR 426 AKYNQL+RIEE E A +AG+NFR Sbjct: 427 LAKYNQLLRIEEAEAGSKARFAGRNFR 453 >gb|AAK41195.1| Enolase [Sulfolobus solfataricus] Length = 419 Score = 356 bits (904), Expect = 3e-97 Identities = 199/428 (46%), Positives = 272/428 (63%), Gaps = 16/428 (3%) Query: 3 MENPYEIVAVIAREILDSRGNPTVEVDVHTPI---SMGRAAVPSGASTGTHEAVELRDGG 59 M N + I V EI+DSRGNPT+ V + T S G A P+GAS GT EAVE+RD Sbjct: 1 MINRFSIEKVKGLEIVDSRGNPTIRVFIRTSDGVESFGDA--PAGASKGTREAVEVRDE- 57 Query: 60 KRYHGKGVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSL 119 +G V+RAV+ VN II P L G+DVR Q ID+LL ++D TENKS LG N I+A S+ Sbjct: 58 ---NGLTVKRAVDIVNYIIDPALHGIDVREQGIIDKLLKDIDSTENKSKLGGNTIIATSI 114 Query: 120 AVAKAAANALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFR 179 A K A+ AL L +++Y+ G +P+PL N+INGG+HAGN L QEF+I+PI N+F+ Sbjct: 115 AALKTASKALGLEVFKYISGPRLPKIPIPLLNIINGGLHAGNKLKIQEFIIVPIKFNTFK 174 Query: 180 EAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPG 239 EA+ + Y LK +I E+YGK VGDEGGF+PP+++ E LD++ +I AGY+ Sbjct: 175 EALFAAIDVYRTLKGLITERYGKIYTAVGDEGGFSPPLEDTREALDLIYTSINNAGYE-- 232 Query: 240 EEIALALDAASSEFY--KDGKYIVSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWE 297 +I + +DAA S+FY K KYI+ G+E +LLE Y +L YPIV +EDPF E ++ Sbjct: 233 GKIYMGMDAAGSDFYDSKKEKYIIDGRELDPNQLLEFYLDLVKQYPIVYLEDPFEENSFD 292 Query: 298 GFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMA 357 F + +L + I GDDL+ TN K LK GIE + +++K NQ+GT++E + +A Sbjct: 293 MFSQLQNKLSSTI-ITGDDLYTTNIKYLKIGIEKRSTKGVIVKPNQVGTISETFEFTNLA 351 Query: 358 FRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGV 417 R ++ SHRSGETED IAD AV + + IK GAPAR +R +KYN+L+ IE + Sbjct: 352 RRNSMKLITSHRSGETEDNFIADFAVGIESDFIKVGAPARGERTSKYNKLLEIENKFG-- 409 Query: 418 AVYAGKNF 425 Y GK F Sbjct: 410 LEYEGKYF 417 >gb|AAB88178.1| (AF035286) alpha enolase [Homo sapiens] Length = 336 Score = 349 bits (885), Expect = 4e-95 Identities = 186/335 (55%), Positives = 234/335 (69%), Gaps = 14/335 (4%) Query: 102 GTENKSNLGANAILAVSLAVAKAAANALELPLYQY---LGGVNAYVLPVPLSNVINGGVH 158 GTENKS GANAIL VSLAV KA A +PLY++ L G + +LPVP NVINGG H Sbjct: 1 GTENKSKFGANAILGVSLAVCKAGAVEKGVPLYRHIADLAGNSEVILPVPAFNVINGGSH 60 Query: 159 AGNDLDFQEFMIMPIGANSFREAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMK 218 AGN L QEFMI+P+GA +FREA+R +E YH LK VI EKYGK+A NVGDEGGFAP + Sbjct: 61 AGNKLAMQEFMILPVGAANFREAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNIL 120 Query: 219 EVTEPLDVLIKAIEEAGYKPGEEIALALDAASSEFYKDGKYIVSGKE-------YTREEL 271 E E L++L AI +AGY +++ + +D A+SEF++ GKY + K + ++L Sbjct: 121 ENKEGLELLKTAIGKAGYT--DKVVIGMDVAASEFFRSGKYDLDFKSPDDPSRYISPDQL 178 Query: 272 LELYKELTSTYPIVSIEDPFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEM 331 +LYK YP+VSIEDPF ++DW + T G +Q+VGDDL VTNPKR+ K + Sbjct: 179 ADLYKSFIKDYPVVSIEDPFDQDDWGAWQKFTASAG--IQVVGDDLTVTNPKRIAKAVNE 236 Query: 332 GAANALLLKVNQIGTLTEAMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIK 391 + N LLLKVNQIG++TE++ A +A G+GV+VSHRSGETED IADL V L GQIK Sbjct: 237 KSCNCLLLKVNQIGSVTESLQACKLAQANGWGVMVSHRSGETEDTFIADLVVGLCTGQIK 296 Query: 392 TGAPARSDRNAKYNQLIRIEEELEGVAVYAGKNFR 426 TGAP RS+R AKYNQL+RIEEEL A +AG+NFR Sbjct: 297 TGAPCRSERLAKYNQLLRIEEELGSKAKFAGRNFR 331 >sp|O26149|ENO_METTH ENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE) (2-PHOSPHO-D-GLYCERATE HYDRO-LYASE) >gi|7436881|pir||A69156 enolase - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2621078|gb|AAB84550.1| (AE000796) enolase [Methanobacterium thermoautotrophicum] Length = 416 Score = 329 bits (835), Expect = 3e-89 Identities = 195/417 (46%), Positives = 262/417 (62%), Gaps = 16/417 (3%) Query: 3 MENPYEIVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGKRY 62 ME+ E V V R+ILDSRGNPTVEVDV T GRAA PSGASTG+ E GG Sbjct: 1 MESIIEDVRV--RKILDSRGNPTVEVDVITWNGFGRAAAPSGASTGSREVAAFPSGG--- 55 Query: 63 HGKGVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVA 122 V + V II+ EL+GMD ++ID +L E+DGTEN S+LG N ++AVS+A A Sbjct: 56 ----VDEIITEVEDIISSELIGMDAVDLQDIDLVLKEIDGTENLSSLGGNTVVAVSMATA 111 Query: 123 KAAANALELPLYQYLGGVNAYVLPVPLSNVINGGVHAG-NDLDFQEFMIMPIGANSFREA 181 KAAA++ +PLY++LGG A +P PL N+INGG HAG N D QEF+++P+GA EA Sbjct: 112 KAAASSYNMPLYRFLGGNLATSIPYPLGNMINGGAHAGKNAPDIQEFLVVPVGAEDITEA 171 Query: 182 IRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEE 241 + + + ++++I +K A GDEGG+ P + + L++ A EE + G E Sbjct: 172 VFANAAVHKRIRELIQKKDPSFAGGKGDEGGWVPSLSN-GDALEIQATACEEVTDELGVE 230 Query: 242 IALALDAASSEFYKDG--KYIVSGKEYTRE--ELLELYKELTSTYPIVSIEDPFHEEDWE 297 + +LD A+SEF+ KY+ + ++ E +E KE+ TY + +EDP HE D E Sbjct: 231 VRPSLDLAASEFWDPEIEKYVYRQENVQKDTGEQIEFVKEIIETYDMYYVEDPLHEGDLE 290 Query: 298 GFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMA 357 GF +T +G + I GDD+FVTN + L++GIEMGAANA+++K NQIGTLT+ +A Sbjct: 291 GFAELTSLVGDRCMICGDDIFVTNREILREGIEMGAANAIIIKPNQIGTLTDTYLTVKLA 350 Query: 358 FRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEEL 414 Y VVSHRSGET D TIA LAVA A IKTGA +R AK N+LIRI+EE+ Sbjct: 351 LENRYTPVVSHRSGETTDDTIAHLAVAFGAPLIKTGA-IGGERIAKLNELIRIQEEI 406 >gb|AAC48992.1| (U23472) enolase homolog; Method: conceptual translation supplied by author [Saccharomyces cerevisiae] Length = 318 Score = 289 bits (733), Expect = 3e-77 Identities = 155/316 (49%), Positives = 206/316 (65%), Gaps = 17/316 (5%) Query: 123 KAAANALELPLYQYLGGV-----NAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANS 177 +AAA + LY+Y+ + + +V+PVP NV+NGG HAG L QEF I P+GA S Sbjct: 1 RAAAAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQS 60 Query: 178 FREAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYK 237 F EA+R SE YH LK + E+YG +A NVGDEGG AP + + LD+++KAI GY+ Sbjct: 61 FAEAMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVKAINICGYE 120 Query: 238 PGEEIALALDAASSEFYKDGKYIVSGKEYTRE--------ELLELYKELTSTYPIVSIED 289 + + +D+A S FYKDGKY ++ KE + +L E Y L YPI+S+ED Sbjct: 121 G--RVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLED 178 Query: 290 PFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTE 349 P+ E+DW + + + VQI+ DDL TN R+ + IE AN LLLK+NQIGTLTE Sbjct: 179 PYAEDDWSSWSAFLKTVN--VQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTE 236 Query: 350 AMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIR 409 +++AA AF AG+GV++SHRSGETED IADL V L GQIK+GA +RS+R AKYN+L+R Sbjct: 237 SIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLR 296 Query: 410 IEEELEGVAVYAGKNF 425 IEEEL +YAG F Sbjct: 297 IEEELGDDCIYAGHRF 312 >gb|AAC39935.1| (U88968) alpha enolase like 1 [Homo sapiens] Length = 269 Score = 280 bits (710), Expect = 1e-74 Identities = 146/268 (54%), Positives = 189/268 (70%), Gaps = 11/268 (4%) Query: 166 QEFMIMPIGANSFREAIRWVSETYHVLKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLD 225 QEFMI+P+GA +FREA+R +E YH LK VI EKYGK+A NVGDEGGFAP + E E L+ Sbjct: 1 QEFMILPVGAANFREAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEGLE 60 Query: 226 VLIKAIEEAGYKPGEEIALALDAASSEFYKDGKYIVSGKE-------YTREELLELYKEL 278 +L AI +AGY +++ + +D A+SEF++ GKY + K + ++L +LYK Sbjct: 61 LLKTAIGKAGYT--DKVVIGMDVAASEFFRSGKYDLDFKSPDDPSRYISPDQLADLYKSF 118 Query: 279 TSTYPIVSIEDPFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALL 338 YP+VSIEDPF ++DW + T G +Q+VGDDL VTNPKR+ K + + N LL Sbjct: 119 IKDYPVVSIEDPFDQDDWGAWQKFTASAG--IQVVGDDLTVTNPKRIAKAVNEKSCNCLL 176 Query: 339 LKVNQIGTLTEAMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARS 398 LKVNQIG++TE++ A +A G+GV+VSHRSGETED IADL V L GQIKTGAP RS Sbjct: 177 LKVNQIGSVTESLQACKLAQANGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRS 236 Query: 399 DRNAKYNQLIRIEEELEGVAVYAGKNFR 426 +R AKYNQL+RIEEEL A +AG+NFR Sbjct: 237 ERLAKYNQLLRIEEELGSKAKFAGRNFR 264 >emb|CAC12011.1| (AL445065) enolase related protein [Thermoplasma acidophilum] Length = 401 Score = 272 bits (689), Expect = 4e-72 Identities = 154/411 (37%), Positives = 245/411 (59%), Gaps = 15/411 (3%) Query: 3 MENPYEIVAVIAREILDSRGNPTVEVDVHTPISMGRAAVPSGASTGTHEAVELRDGGKRY 62 ME P E + V R++LDSRGN TVE DV P GR + P+GASTG E + + Sbjct: 1 MELPIEEIKV--RKVLDSRGNFTVEADVTVPNGFGRTSAPAGASTGETEVIA-------F 51 Query: 63 HGKGVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVA 122 G+ +++ + L+G + Q D+LL ++DG+ N SNLG N A+S++VA Sbjct: 52 SKSGIDASIQFFESKVKRSLIGFNALDQSGFDKLLTDIDGSGNFSNLGGNLATALSMSVA 111 Query: 123 KAAANALELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNDLDFQEFMIMPIGANSFREAI 182 KAAA +L +PLY+Y+GG+ + +P P+ NVI GG HA N QEF++ G+ A Sbjct: 112 KAAAQSLGIPLYRYVGGIRS-TIPRPMGNVIGGGKHARNGTSIQEFLVSAQGSTFLESA- 169 Query: 183 RWVSETYHV-LKKVIAEKYGKNAVNVGDEGGFAPPMKEVTEPLDVLIKAIEEAGYKPGEE 241 +++ H + ++++K+ ++ VGDE ++ + + E ++L +A++E + + Sbjct: 170 -YINVLVHRRIGDMLSDKFKDISIGVGDERTWSVNLSD-EEAFEILNEAVKEISSEKKVK 227 Query: 242 IALALDAASSEFYKDGKYIVSGKEYTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVM 301 I +D A+ Y++GKY+ +R+E ++ ++ + + IEDP ++ D++GF Sbjct: 228 IYTGVDFAADSLYENGKYVYKHTTKSRDEQIDYAISISKDFGVYYIEDPMYDTDFDGFAE 287 Query: 302 ITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAG 361 IT +G + IVGDDL+ TNP R++KG+E + NA+L+KVNQIGTL+ A +A +A AG Sbjct: 288 ITARIGDRSLIVGDDLYTTNPDRIRKGVEKKSTNAVLIKVNQIGTLSAAREAVAVATFAG 347 Query: 362 YGVVVSHRSGETEDATIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEE 412 +VSHRSGET D +A L+VA + +KTG +R AK N++ RIEE Sbjct: 348 MKNIVSHRSGETTDDFLAHLSVAFGSTFVKTGV-IGGERVAKLNEIARIEE 397 >emb|CAB94588.1| (AL359213) ENO3, muscle enolase 3 beta [Homo sapiens] Length = 154 Score = 170 bits (426), Expect = 3e-41 Identities = 87/151 (57%), Positives = 107/151 (70%), Gaps = 2/151 (1%) Query: 276 KELTSTYPIVSIEDPFHEEDWEGFVMITRELGKKVQIVGDDLFVTNPKRLKKGIEMGAAN 335 K YP+VSIEDPF ++DW + G +QIVGDDL VTNPKR+ + +E A N Sbjct: 1 KSFIKNYPVVSIEDPFDQDDWATWTSFLS--GVNIQIVGDDLTVTNPKRIAQAVEKKACN 58 Query: 336 ALLLKVNQIGTLTEAMDAAYMAFRAGYGVVVSHRSGETEDATIADLAVALNAGQIKTGAP 395 LLLKVNQIG++TE++ A +A G+GV+VS RSGETED IADL V L GQIKTGAP Sbjct: 59 CLLLKVNQIGSVTESIQACKLAQSNGWGVMVSXRSGETEDTFIADLVVGLCTGQIKTGAP 118 Query: 396 ARSDRNAKYNQLIRIEEELEGVAVYAGKNFR 426 RS+R AKYNQL+RIEE L A++AG+ FR Sbjct: 119 CRSERLAKYNQLMRIEEALGDKAIFAGRKFR 149 >gi|10835228 MYC promoter-binding protein 1 [Homo sapiens] >gi|126792|sp|P22712|MBP1_HUMAN C-MYC PROMOTER-BINDING PROTEIN >gi|105479|pir||A39579 c-myc promoter-binding protein MBP-1 - human >gi|180663|gb|AAA35698.1| (M55914) c-myc binding protein [Homo sapiens] Length = 335 Score = 155 bits (389), Expect = 6e-37 Identities = 98/230 (42%), Positives = 131/230 (56%), Gaps = 20/230 (8%) Query: 208 GDEGGFAPPMKEVTEPLDVLIKAIEEAGY--KPGEEIALALDAASSEFYKDGKYIVSGKE 265 GD GFAP + E E L++L AI + G K G +D A+SEF++ G Y + K Sbjct: 110 GDLRGFAPNILENKEGLELLKTAIGKPGLHCKGGH----GMDVAASEFFRSGNYDLDFKS 165 Query: 266 -------YTREELLELYKELTSTYPIVSIEDPFHEEDWEGFVMIT--RELGKKVQIVGDD 316 + ++L +LYK YP+VSIEDPF ++DW + + R G D Sbjct: 166 PDDPSRYISPDQLADLYKSFIKDYPVVSIEDPFDQDDWGASEVHSQCRNPGSGGMTHSDQ 225 Query: 317 LFVTNPKRLKKGIEMGAANALLLKVNQIGTLTEAMDAAYMAFRAGYGVVVSHRSGETEDA 376 PK ++G+ + N LLLKVNQIG++TE++ A +A G+GV+VSHRSGETED Sbjct: 226 -----PKEDRQGVNEKSCNCLLLKVNQIGSVTESLQACKLAQANGWGVMVSHRSGETEDT 280 Query: 377 TIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGVAVYAGKNFR 426 IADL V L G + P R AKYNQL+RIEEEL A +AG+NFR Sbjct: 281 FIADLVVGLCTGADQDWCPLPITRLAKYNQLLRIEEELGSKAKFAGRNFR 330 >gb|AAA24486.1| (M12843) enolase [Escherichia coli] Length = 123 Score = 136 bits (338), Expect = 6e-31 Identities = 76/121 (62%), Positives = 91/121 (74%), Gaps = 2/121 (1%) Query: 8 EIVAVIAREILDSRGNPTVEVDVHTPIS-MGRAAVPSGASTGTHEAVELRDGGK-RYHGK 65 +IV +I REI+DSRGNPTVE +VH +G AA PSGASTG+ EA+ELRDG K R+ GK Sbjct: 3 KIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGK 62 Query: 66 GVRRAVENVNKIIAPELVGMDVRWQREIDRLLIELDGTENKSNLGANAILAVSLAVAKAA 125 GV +AV VN IA L+G D + Q ID+++I+LDGTE KS GANAILAVSLA AKAA Sbjct: 63 GVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTEKKSKFGANAILAVSLANAKAA 122 Query: 126 A 126 A Sbjct: 123 A 123 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.316 0.135 0.379 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 157371683 Number of Sequences: 2977 Number of extensions: 6660545 Number of successful extensions: 18966 Number of sequences better than 1.0e-10: 216 Number of HSP's better than 0.0 without gapping: 210 Number of HSP's successfully gapped in prelim test: 6 Number of HSP's that attempted gapping in prelim test: 17833 Number of HSP's gapped (non-prelim): 221 length of query: 430 length of database: 189,106,746 effective HSP length: 60 effective length of query: 370 effective length of database: 153,197,526 effective search space: 56683084620 effective search space used: 56683084620 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.5 bits) S2: 166 (69.1 bits)