BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB1138 (PAB1138) DE:NADH-dependent DYHYDROGENASE RELATED PROTEIN (341 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||A75025 NADH-dependent dyhydrogenase related protein PAB1138... 692 0.0 pir||D71201 hypothetical protein PH1881 - Pyrococcus horikoshii ... 651 0.0 pir||H69216 3-chlorobenzoate-3,4-dioxygenase dyhydrogenase relat... 132 4e-30 pir||E75096 NADH-dependent dehydrogenase homolog. PAB0775 - Pyro... 132 7e-30 pir||D72381 dehydrogenase - Thermotoga maritima (strain MSB8) >g... 127 1e-28 dbj|BAB04967.1| (AP001511) NADH-dependent dyhydrogenase [Bacillu... 126 4e-28 gb|AAC23913.1| (AF039207) NADH-dependent dehydrogenase homolog [... 122 5e-27 pir||B72359 lipopolysaccharide biosynthesis protein BplA - Therm... 120 2e-26 pir||B75025 NADH-dependent dyhydrogenase related protein PAB1139... 116 5e-25 sp|O05389|YRBE_BACSU HYPOTHETICAL 37.8 KDA PROTEIN IN CSBX-NADA ... 113 2e-24 sp|P40332|YISS_BACSU HYPOTHETICAL 37.5 KD PROTEIN IN DEGA-NPRB I... 113 2e-24 pir||E71201 probable glucose-fructose oxidoreductase - Pyrococcu... 112 5e-24 gb|AAK43115.1| Dehydrogenase, putative [Sulfolobus solfataricus] 107 2e-22 gb|AAK43149.1| Dehydrogenase, putative [Sulfolobus solfataricus] 106 5e-22 gb|AAC01706.1| (AF040570) unknown [Amycolatopsis mediterranei] 104 2e-21 gb|AAK43117.1| Dehydrogenase, putative [Sulfolobus solfataricus] 104 2e-21 emb|CAB88961.1| (AL353864) putative oxidoreductase. [Streptomyce... 103 3e-21 gb|AAC31183.1| (AF076240) putative NADH-inositol dehydrogenase M... 98 2e-19 sp|O68965|MI2D_RHIME MYO-INOSITOL 2-DEHYDROGENASE >gi|3088561|gb... 95 1e-18 emb|CAB60174.1| (AL132824) putative dehydrogenase [Streptomyces ... 94 3e-18 dbj|BAB05884.1| (AP001514) unknown conserved protein [Bacillus h... 94 3e-18 pir||S76068 hypothetical protein - Synechocystis sp. (strain PCC... 93 4e-18 pir||A69834 conserved hypothetical protein yhjJ - Bacillus subti... 93 4e-18 dbj|BAB06035.1| (AP001515) myo-inositol 2-dehydrogenase [Bacillu... 90 3e-17 sp|P26935|MI2D_BACSU MYO-INOSITOL 2-DEHYDROGENASE >gi|80338|pir|... 90 4e-17 gb|AAK43113.1| Dehydrogenase, putative [Sulfolobus solfataricus] 89 8e-17 emb|CAC11912.1| (AL445065) hypothetical protein [Thermoplasma ac... 88 1e-16 pir||A82502 oxidoreductase, Gfo/Idh/MocA family VCA0099 [importe... 88 2e-16 sp|P49307|MOCA_RHIME RHIZOPINE CATABOLISM PROTEIN MOCA >gi|21208... 87 4e-16 dbj|BAB05939.1| (AP001514) dehydrogenase [Bacillus halodurans] 86 5e-16 emb|CAC12307.1| (AL445066) glucose-fructose oxidoreductase relat... 86 5e-16 dbj|BAB05940.1| (AP001514) unknown conserved protein [Bacillus h... 86 7e-16 pir||S70672 dehydrogenase homolog - Bordetella pertussis >gi|992... 85 9e-16 emb|CAB02496.1| (Z80356) glucose-fructose oxidoreductase [Zymomo... 85 1e-15 pdb|1OFG|A Chain A, Glucose-Fructose Oxidoreductase >gi|2098324|... 85 1e-15 gb|AAD45293.1|AF156256_1 (AF156256) putative dehydrogenase [Vibr... 84 2e-15 sp|O32223|YVAA_BACSU HYPOTHETICAL OXIDOREDUCTASE IN FHUD-OPUBD I... 83 4e-15 sp|P74041|Y816_SYNY3 HYPOTHETICAL 41.5 KD PROTEIN SLL0816 >gi|74... 81 2e-14 pir||B75475 glucose-fructose oxidoreductase - Deinococcus radiod... 81 2e-14 gb|AAD50452.1|AF170704_2 (AF170704) SpcB [Streptomyces spectabilis] 80 4e-14 sp|P49305|YMO1_RHIME HYPOTHETICAL 36.4 KD PROTEIN IN MOCC-MOCA I... 80 5e-14 gb|AAF63338.1|AF244574_1 (AF244574) myo-inositol-2-dehydrogenase... 79 6e-14 pir||T44834 hypothetical protein weeE [imported] - Acinetobacter... 79 8e-14 pir||T38428 hypothetical oxidoreductase - fission yeast (Schizo... 78 1e-13 sp|Q05184|PHT4_PSEPU PUTATIVE 4,5,-DIHYDROXYPHTHALATE DEHYDROGEN... 78 2e-13 pir||G72391 conserved hypothetical protein - Thermotoga maritima... 77 2e-13 pir||A83004 conserved hypothetical protein PA5149 [imported] - P... 77 2e-13 gb|AAF13758.1|AF117351_15 (AF117351) MviM [Zymomonas mobilis] 77 3e-13 pir||T39296 Oxidoreductase - fission yeast (Schizosaccharomyces ... 76 4e-13 gb|AAD45545.1|U70376_10 (U70376) SpcB [Streptomyces flavopersicus] 76 4e-13 emb|CAB65577.1| (AL136058) putative oxidoreductase. [Streptomyce... 75 1e-12 gb|AAG09709.1|AF218837_4 (AF218837) unknown [Pasteurella multocida] 75 1e-12 emb|CAC11395.1| (AL445063) glucose-fructose oxidoreductase relat... 75 2e-12 sp|Q07982|GFO_ZYMMO GLUCOSE--FRUCTOSE OXIDOREDUCTASE PRECURSOR (... 74 3e-12 dbj|BAB07562.1| (AP001520) oxidoreductase [Bacillus halodurans] 74 3e-12 gb|AAD03557.1| (AF095748) phthalate dihydrodiol dehydrogenase [B... 73 4e-12 dbj|BAA97119.1| (AB035122) 4-carboxy-2-hydroxymuconate-6-semiald... 73 5e-12 pir||A81396 hypothetical protein Cj0504c [imported] - Campylobac... 73 5e-12 pir||T36464 probable oxidoreductase - Streptomyces coelicolor >g... 73 6e-12 pir||B64919 conserved hypothetical protein b1624 - Escherichia c... 72 1e-11 sp|P77376|YDGJ_ECOLI HYPOTHETICAL OXIDOREDUCTASE IN ADD-NTH INTE... 72 1e-11 gb|AAF51262.1| (AE003583) CG3609 gene product [Drosophila melano... 70 3e-11 sp|Q44258|CBAC_ALCSB 1-CARBOXY-3-CHLORO-3,4-DIHYDROXYCYCLO HEXA-... 70 4e-11 sp|P09400|STRI_STRGR STREPTOMYCIN BIOSYNTHESIS PROTEIN STRI >gi|... 69 7e-11 dbj|BAB04427.1| (AP001509) unknown conserved protein [Bacillus h... 69 7e-11 pir||T42744 hypothetical protein - fission yeast (Schizosaccharo... 69 9e-11 gb|AAF97051.1| (AF248034) WlbA [Bordetella avium] 69 9e-11 >pir||A75025 NADH-dependent dyhydrogenase related protein PAB1138 - Pyrococcus abyssi (strain Orsay) >gi|5459153|emb|CAB50639.1| (AJ248288) NADH-dependent DYHYDROGENASE RELATED PROTEIN [Pyrococcus abyssi] Length = 341 Score = 692 bits (1767), Expect = 0.0 Identities = 341/341 (100%), Positives = 341/341 (100%) Query: 1 MPEKLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLD 60 MPEKLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLD Sbjct: 1 MPEKLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLD 60 Query: 61 EFLEQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKL 120 EFLEQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKL Sbjct: 61 EFLEQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKL 120 Query: 121 FVGHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPADYWYWDESKSGGVIVDLGV 180 FVGHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPADYWYWDESKSGGVIVDLGV Sbjct: 121 FVGHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPADYWYWDESKSGGVIVDLGV 180 Query: 181 HVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWSYPMP 240 HVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWSYPMP Sbjct: 181 HVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWSYPMP 240 Query: 241 PKYGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPRFSPMLSTFPQAFEAELRHFF 300 PKYGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPRFSPMLSTFPQAFEAELRHFF Sbjct: 241 PKYGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPRFSPMLSTFPQAFEAELRHFF 300 Query: 301 ECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKVEVN 341 ECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKVEVN Sbjct: 301 ECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKVEVN 341 >pir||D71201 hypothetical protein PH1881 - Pyrococcus horikoshii >gi|3258320|dbj|BAA31003.1| (AP000007) 371aa long hypothetical protein [Pyrococcus horikoshii] Length = 371 Score = 651 bits (1660), Expect = 0.0 Identities = 313/341 (91%), Positives = 334/341 (97%) Query: 1 MPEKLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLD 60 M E+LKVG+IGCGNIFNLAHKPAL+SLRTIAKVVAVMDI+EEAA+KAGKELNAKVFTSLD Sbjct: 31 MSERLKVGVIGCGNIFNLAHKPALRSLRTIAKVVAVMDINEEAAKKAGKELNAKVFTSLD 90 Query: 61 EFLEQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKL 120 EFLEQDM+VVE+LTPTYTHAE+AI+ALKAGKHVIVEKPIALT EEAEKMIKEAE Q LKL Sbjct: 91 EFLEQDMDVVEVLTPTYTHAEIAIKALKAGKHVIVEKPIALTSEEAEKMIKEAEEQGLKL 150 Query: 121 FVGHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPADYWYWDESKSGGVIVDLGV 180 FVGHVRRFDKRW QIK++IK+RNILPMQIRKIEVQHLPFPADYWYWDESKSGGVI+DLGV Sbjct: 151 FVGHVRRFDKRWTQIKEVIKTRNILPMQIRKIEVQHLPFPADYWYWDESKSGGVIIDLGV 210 Query: 181 HVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWSYPMP 240 HVTDFLRWFFESEP+EVFAVGKAIRGEARVNKT+DHVVMFIKFEG KTGIGEVSWSYPM Sbjct: 211 HVTDFLRWFFESEPVEVFAVGKAIRGEARVNKTYDHVVMFIKFEGNKTGIGEVSWSYPMT 270 Query: 241 PKYGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPRFSPMLSTFPQAFEAELRHFF 300 PKYGVFYHHLDIIGKNGRIRYTP+DTPVVGV+KSSFEMPRFSPMLSTFPQAFEAELRHFF Sbjct: 271 PKYGVFYHHLDIIGKNGRIRYTPLDTPVVGVIKSSFEMPRFSPMLSTFPQAFEAELRHFF 330 Query: 301 ECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKVEVN 341 ECIKS+CEPVVTA+DALIAL+IAEKA+ESIKKGEPVKVEVN Sbjct: 331 ECIKSNCEPVVTARDALIALQIAEKARESIKKGEPVKVEVN 371 >pir||H69216 3-chlorobenzoate-3,4-dioxygenase dyhydrogenase related protein - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2621968|gb|AAB85373.1| (AE000863) 3-chlorobenzoate-3,4-dioxygenase dyhydrogenase related protein [Methanobacterium thermoautotrophicum] Length = 318 Score = 132 bits (330), Expect = 4e-30 Identities = 99/338 (29%), Positives = 163/338 (47%), Gaps = 29/338 (8%) Query: 4 KLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFL 63 ++ VG+IG G + H L+ A ++AV DI + +K + + + + L Sbjct: 3 QINVGVIGVGAM-GYNHARVYYRLKN-ANLMAVSDIMKGTLQKVANKYDTVGYVDYENLL 60 Query: 64 E-QDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFV 122 E ++ VV + PT H + ++AL+ KHV+VEKPIA T+EEAE M+K A + LKL Sbjct: 61 EIPEIEVVSVCVPTTHHYNVVMDALEHDKHVLVEKPIAFTLEEAEDMVKTARKKGLKLGT 120 Query: 123 GHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPADYWYWDESKSGGVIVDLGVHV 182 GHV RF+ + K++I++ +++ + + PFP K GV +DL +H Sbjct: 121 GHVERFNPAVQKAKELIEN-DVIGDVVSASAKRVGPFP------PRIKDVGVTIDLAIHD 173 Query: 183 TDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWSYPMPPK 242 D + + F EV+AV +I + + DH + KF+ G TGI EV+W P + Sbjct: 174 LDVMHYLFSEPVAEVYAVMGSILEKC---EYEDHAEIMTKFKSGITGILEVNWLTPYKRR 230 Query: 243 YGVFYHHLDIIGKNG--RIRYTPMDTPVVGVVKSSFEMPRFSPMLSTFPQAFEAELRHFF 300 L I G +G + Y V G ++ P+ + E++ F Sbjct: 231 ------KLAITGTDGIINVDYIDQRLDVYGKFAQDVDIKHEEPL--------KNEIKSFL 276 Query: 301 ECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKV 338 + + EP +T +D + AL+ A +S ++ PVKV Sbjct: 277 MSVINDEEPEITGEDGIYALRTVLAAMKSAREHRPVKV 314 >pir||E75096 NADH-dependent dehydrogenase homolog. PAB0775 - Pyrococcus abyssi (strain Orsay) >gi|5458586|emb|CAB50074.1| (AJ248286) NADH-DEPENDENT DEHYDROGENASE HOMOLOG. [Pyrococcus abyssi] Length = 315 Score = 132 bits (328), Expect = 7e-30 Identities = 96/347 (27%), Positives = 165/347 (46%), Gaps = 46/347 (13%) Query: 5 LKVGIIGCGNIFNLAHKPALKSLRTIAKV--VAVMDIDEEAARKAGKELNAKVFTSLDEF 62 ++VG++G G + H L KV + V DI+ E A++ + + F E Sbjct: 1 MRVGVVGVGKM-GYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYREL 59 Query: 63 LEQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFV 122 +++ ++ V I PT H E+ ++ ++ V+VEKPIA ++E A+++IK A+ + L V Sbjct: 60 IKEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMV 119 Query: 123 GHVRRFDKRWIQIKDIIK-----------SRNILPMQIRKIEVQHLPFPADYWYWDESKS 171 GHV RF+ +++K+ I+ ++ + PM R +V Sbjct: 120 GHVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTRISDV----------------- 162 Query: 172 GGVIVDLGVHVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIG 231 GVI+DL VH D + + S IEV+A + ++ A+V D+ ++ + FE G GI Sbjct: 163 -GVIIDLAVHDIDVMSFLTTSRVIEVYAKARNVKHPAKV---EDYALILLSFENGANGII 218 Query: 232 EVSWSYPMPPKYGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPRFSPMLSTFPQA 291 E + P + L+++G G I Y + + + + Sbjct: 219 ETNRLTPHKTR------TLNVVGTEG-IAYLDYINQELTLYNEEW----IYKAKINKEEP 267 Query: 292 FEAELRHFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKV 338 + E+ HF EC+K +P+V ++ L ALK+A KA ES KK E V+V Sbjct: 268 LKLEIEHFLECVKEGKKPLVGGEEGLHALKVAVKALESSKKDEVVRV 314 >pir||D72381 dehydrogenase - Thermotoga maritima (strain MSB8) >gi|4980919|gb|AAD35499.1|AE001720_13 (AE001720) dehydrogenase [Thermotoga maritima] Length = 334 Score = 127 bits (317), Expect = 1e-28 Identities = 99/342 (28%), Positives = 174/342 (49%), Gaps = 19/342 (5%) Query: 5 LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNA-KVFTSLDEFL 63 +++G+IG G I + H LK + A + A+ D+ E+ R+ ++L K + E + Sbjct: 1 MRIGVIGLGRIGTI-HAENLKMIDD-AILYAISDVREDRLREMKEKLGVEKAYKDPHELI 58 Query: 64 EQ-DMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFV 122 E +++ V + + T TH+EL I KA KHV EKP++L + + ++MI+E + ++ LF Sbjct: 59 EDPNVDAVLVCSSTNTHSELVIACAKAKKHVFCEKPLSLNLADVDRMIEETKKADVILFT 118 Query: 123 GHVRRFDKRWIQIKDIIKSRNI-LPMQIRKIEVQHLPFPADYWYWDESKSGGVIVDLGVH 181 G RRFD+ + ++K+ +++ I P +R P P DY SGG+ +D+ +H Sbjct: 119 GFNRRFDRNFKKLKEAVENGTIGKPHVLRITSRDPAPPPLDY----IRVSGGIFLDMTIH 174 Query: 182 VTDFLRWFFESEPIEVFAVGKAIRGEARVNKTH--DHVVMFIKFEGGKTGIGEVSWSYPM 239 D R+ E EVFA G + E + K D V+ ++F+ G G+ + S Sbjct: 175 DFDMARYIMGEEVEEVFADGSVLVDE-EIGKAGDVDTAVVVLRFKSGALGVIDNS----R 229 Query: 240 PPKYGVFYHHLDIIGKNGRI-RYTPMDTPVVGVVKSSFEMPRFSP-MLSTFPQAFEAELR 297 YG + +++ G GRI +T VV + R+ L + ++ EL+ Sbjct: 230 RAVYG-YDQRIEVFGSKGRIFADNVRETTVVLTDEQGDRGSRYLYFFLERYRDSYLEELK 288 Query: 298 HFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKVE 339 F + +KS P V+ +D +AL + AK+S+++ VK+E Sbjct: 289 TFIKNVKSGEPPAVSGEDGKMALLLGYAAKKSLEEKRSVKLE 330 >dbj|BAB04967.1| (AP001511) NADH-dependent dyhydrogenase [Bacillus halodurans] Length = 340 Score = 126 bits (313), Expect = 4e-28 Identities = 101/362 (27%), Positives = 163/362 (44%), Gaps = 53/362 (14%) Query: 5 LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFLE 64 L+V +IGCG+I H P + +VAV D EE A+K K A +T + LE Sbjct: 4 LRVAVIGCGSIAQHRHLPEYEQ-NPHTTIVAVCDPVEERAKKVAKLYGAIAYTDHMQLLE 62 Query: 65 -QDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVG 123 +++++V + TP HA ++I+ALKAG HV+ EKP+A + EE E MIK AE + L +G Sbjct: 63 KEEIDLVSVCTPNAYHAPISIDALKAGTHVLCEKPMATSAEECEAMIKAAEEAGMCLMIG 122 Query: 124 HVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQH------LPFPADYWYWDESKSG-GVIV 176 H +RF + + +I + +I + + H + W++ + ++ G + Sbjct: 123 HNQRFVSSHEKARQLIATGDIGKIYSFRTTFGHGGPEGWSVDGENSWFFKKDQAFIGAMG 182 Query: 177 DLGVHVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWS 236 DLGVH D LR+ E +E VG + A+ D+ V +K E G G SWS Sbjct: 183 DLGVHKADLLRYLLGEEVVE---VGAFVTTSAKQGDVDDNAVAILKTESGIVGTLTASWS 239 Query: 237 YPM-------------------PPKYGVFYHHLDIIGKNGR-IRYTPMDTPVVGVVKSSF 276 Y P Y + H+ KNG ++Y +G ++S+ Sbjct: 240 YVAKEDNSTILYGENAILRLEDDPHYSLIVHY-----KNGETVKYE------LGQIQSND 288 Query: 277 EMPRFSPMLSTFPQAFEAELRHFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPV 336 E Q + HF + EP ++ ++ +L I A E+ + G + Sbjct: 289 E----------GGQTDSRVIAHFVNSVLEGKEPPISGKEGYASLNIILAAMEASRTGRTI 338 Query: 337 KV 338 K+ Sbjct: 339 KL 340 >gb|AAC23913.1| (AF039207) NADH-dependent dehydrogenase homolog [Listeria monocytogenes] Length = 358 Score = 122 bits (304), Expect = 5e-27 Identities = 106/358 (29%), Positives = 161/358 (44%), Gaps = 31/358 (8%) Query: 5 LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKEL---NAKVFTSLDE 61 LKVGIIGCG I N H P+L A++VA DI E A A KE NA V+T+ E Sbjct: 3 LKVGIIGCGGIANGKHMPSLLKAEK-AEMVAFCDIVLEKAEAAAKEFGGENASVYTNYVE 61 Query: 62 FLE-QDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKL 120 L+ + ++V+ + TP +HAE++I A++AGKHV+ EKP+A T EA+ MI+ AE KL Sbjct: 62 LLQDKSIDVIHVCTPNISHAEISIAAMEAGKHVMCEKPMAKTTAEAKSMIEAAERTGKKL 121 Query: 121 FVGHVRRFDKRWIQIKDIIKSRNILPMQIRKIE-VQHLPFPADYWYWD-ESKSGGVIVDL 178 +G+ RF K + + ++ + + K + ++ P + D E++ GG ++D+ Sbjct: 122 TIGYQNRFRKDSDYLHQVCENGELGDIYYAKAKAIRRRAVPTWGVFLDEEAQGGGPLIDI 181 Query: 179 GVHVTDFLRWFFESEPIEVFAVG----KAIRGEARVN----------KTHDHVVMFIKFE 224 G H D W ++ + + VG K + E N D FI E Sbjct: 182 GTHALDLTLWMMDNYKPK-YVVGNSYHKLAKKENAANAWGSWDPNKFTVEDSAFGFITME 240 Query: 225 GGKTGIGEVSWSYPMPPKYGVFYHHLDIIGKNG------RIRYTPMDTPVVGVVKSSFEM 278 G T + E SW+ V + G G +R + K E Sbjct: 241 NGATIVLEASWAL---NTLDVGEARTSLSGTEGGADMEDGLRINGEAHSQMYEKKIQLEA 297 Query: 279 PRFSPMLSTFPQAFEAELRHFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPV 336 T E + I+ + +PVV A++ +I E ES K G+PV Sbjct: 298 GGVDFYDGTGDDPALIEAGQWLGAIEKNTDPVVKPGQAIVVTQILEAIYESSKTGQPV 355 >pir||B72359 lipopolysaccharide biosynthesis protein BplA - Thermotoga maritima (strain MSB8) >gi|4981103|gb|AAD35670.1|AE001733_7 (AE001733) lipopolysaccharide biosynthesis protein BplA [Thermotoga maritima] Length = 360 Score = 120 bits (299), Expect = 2e-26 Identities = 93/355 (26%), Positives = 166/355 (46%), Gaps = 33/355 (9%) Query: 4 KLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNA------KVFT 57 KL++ ++GCG I H PAL + + + VAV D+ EE A +A + + T Sbjct: 2 KLRIALVGCGRIGQKKHVPALIETQDLFETVAVCDLVEERANRAAEHFEKSGLRRPETMT 61 Query: 58 SLDEFLE-QDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQ 116 + E L+ +D++V+ I T + H ++ +EAL+AGKHV+VEKP+AL+ + +M++ ++ + Sbjct: 62 NYRELLKREDVDVISIATESGKHYQITMEALEAGKHVLVEKPMALSTKHMNEMVELSKQK 121 Query: 117 ELKLFVGHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPADY----WYWDESKSG 172 LKL V RF+ +++ + S + + V+ Y W G Sbjct: 122 NLKLGVFFQNRFNPPVQEVRKKLDSGAFGKIFYASVAVRWNRNEDYYKQASWRGTWEMDG 181 Query: 173 GVIVDLGVHVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGE 232 GV+++ H D L+WF E E++ G + D +KF+GGKTG+ E Sbjct: 182 GVLMNQSTHAIDLLQWFLGGEIEEIY--GHIANTNHPYIEAEDEGFAIVKFKGGKTGLIE 239 Query: 233 VSWSYPMPPKYGVFYHHLD----IIGKNGRIRYTPMDTPVVGVVKSSFEMPRFSPML--- 285 + VF +L+ I G+ G + + V ++ FE P + Sbjct: 240 AT--------SNVFPRNLEETLAIFGEKGTVVIGGI--AVNRILTWRFEGEEGHPFMNLP 289 Query: 286 ---STFPQAFEAELRHFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVK 337 + + + + R F+E + + +P ++ +D A++I S +G PVK Sbjct: 290 DPDTVYGDSHKYVYRDFYEAVTNDRKPYISGEDGKKAVEIVLGIYRSFLEGRPVK 344 >pir||B75025 NADH-dependent dyhydrogenase related protein PAB1139 - Pyrococcus abyssi (strain Orsay) >gi|5459154|emb|CAB50640.1| (AJ248288) NADH-dependent DYHYDROGENASE RELATED PROTEIN [Pyrococcus abyssi] Length = 335 Score = 116 bits (287), Expect = 5e-25 Identities = 100/348 (28%), Positives = 165/348 (46%), Gaps = 40/348 (11%) Query: 15 IFNLAHKPALKSLRTI-----AKVVAVMD--IDEEAARKAGKELNAKVFTSLDEFL-EQD 66 + + AH AL+ TI AK+VA+ + A+ K+ AK + ++ L ++ Sbjct: 6 VISYAHPHALRYAATIRANRRAKLVAISGDGANSGLAKIEAKKYGAKFYQDYEKLLRDES 65 Query: 67 MNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVGHVR 126 + V I TY H E+AI A + GK +++EKPIALT+E+ ++++K A +KL V Sbjct: 66 VEAVYIAIETYRHKEVAIRAAEEGKDILLEKPIALTLEDGKEIVKAARKAGVKLMVPFNP 125 Query: 127 RFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPA------DYWYWDESKS-GGVIVDLG 179 RF + + K++I+ I ++ +++ P W++D KS GG +D Sbjct: 126 RFTQPLQKAKEMIEKGEIGKLEYIYTISEYVKPPMFLEGIDTSWFFDIKKSGGGGFMDTA 185 Query: 180 VHVTDFLRWFFESEPIEVFA-VGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWSYP 238 H D L W ESEPI V+A +G I G + D I+F+ G + W+ P Sbjct: 186 PHGIDSLFWLTESEPIRVYADIGPKIWG----FQVDDIGTALIEFKNGVIAVLTAGWANP 241 Query: 239 MPPKYGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPRFSPMLSTFPQAF------ 292 YG+ + I+G +G + ++S++ P F+ + F Sbjct: 242 KGYPYGLEIKYY-IVGDDGFLD-----------IRSAY--PDFTVYQDKTEKIFWERADV 287 Query: 293 EAELRHFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKVEV 340 E + F + I+ EP +T +DAL L + A ES K G+ VKVE+ Sbjct: 288 EGIVNAFIDAIQQDKEPPITGEDALKNLAVVLAAYESSKTGKAVKVEL 335 >sp|O05389|YRBE_BACSU HYPOTHETICAL 37.8 KDA PROTEIN IN CSBX-NADA INTERGENIC REGION (ORF1) >gi|7429795|pir||D69972 opine catabolism homolog yrbE - Bacillus subtilis >gi|2635242|emb|CAB14737.1| (Z99118) similar to opine catabolism [Bacillus subtilis] >gi|6977802|emb|CAB75327.1| (Y15896) hypothetical protein [Bacillus subtilis] Length = 341 Score = 113 bits (281), Expect = 2e-24 Identities = 96/345 (27%), Positives = 159/345 (45%), Gaps = 17/345 (4%) Query: 1 MPEKLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTS-- 58 M +++ GIIG G I L H + + + K+ A+ DI + + TS Sbjct: 1 MTKQIVTGIIGAGRIGKL-HVQNISRIPHM-KIKAISDIQASRIKSWADSHQIEYITSDY 58 Query: 59 LDEFLEQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQEL 118 D + D++ + I +PT HA++ EA +A KH+ EKP++ +++E + + + Sbjct: 59 RDLLHDPDIDAIFICSPTAVHAQMIKEAAEAKKHIFCEKPVSFSLDETSEALAAVRKHGV 118 Query: 119 KLFVGHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPADYWYWDESKSGGVIVDL 178 L VG RRFD + +IK I+++ I + KI + P P + Y SGG+ +D+ Sbjct: 119 TLQVGFNRRFDPHFKKIKTIVENGEIGTPHLLKITSRD-PEPPNIDY--VRTSGGLFMDM 175 Query: 179 GVHVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTH-DHVVMFIKFEGGKTGIGEVSWSY 237 +H D R+ SE EV+A G A+ + D V+ + FE G + + S Sbjct: 176 SIHDFDMARYIMGSEVTEVYAKGAALVNPSFAELGDIDTAVITLTFENGAMAVIDNS--- 232 Query: 238 PMPPKYGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEM---PRFSPMLSTFPQAFEA 294 YG + +++ G G V V + F M P F L + ++E Sbjct: 233 -RQAVYG-YDQRVEVFGTKGSAAADNSRPTTVEVSTADFVMKDKPHFF-FLERYKDSYEE 289 Query: 295 ELRHFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKVE 339 E+ F E I ++ E T D L A +IA A++S+ G PV +E Sbjct: 290 EILRFAEAIGTNQETPCTGNDGLQAGRIARAAQQSLAFGMPVSIE 334 >sp|P40332|YISS_BACSU HYPOTHETICAL 37.5 KD PROTEIN IN DEGA-NPRB INTERGENIC REGION >gi|7429794|pir||B69838 myo-inositol 2-dehydrogenase homolog yisS - Bacillus subtilis >gi|1934841|emb|CAB07962.1| (Z93940) unknown [Bacillus subtilis] >gi|2145385|emb|CAA70648.1| (Y09476) YisS [Bacillus subtilis] >gi|2633420|emb|CAB12924.1| (Z99109) alternate gene name: yuxD, yucG~similar to myo-inositol 2-dehydrogenase [Bacillus subtilis] Length = 342 Score = 113 bits (281), Expect = 2e-24 Identities = 95/350 (27%), Positives = 168/350 (47%), Gaps = 25/350 (7%) Query: 1 MPEKLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLD 60 M +++ ++G G + H L + AK+V V D + A + +EL + ++ Sbjct: 1 MEHQVRCAVLGLGRL-GYYHAKNLVTSVPGAKLVCVGDPLKGRAEQVARELGIEKWSEDP 59 Query: 61 EFLEQD--MNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQEL 118 + +D ++ V I+TPT TH ++ I+A + GK + VEKP+ L++EE++ ++ + + Sbjct: 60 YEVLEDPGIDAVIIVTPTSTHGDMIIKAAENGKQIFVEKPLTLSLEESKAASEKVKETGV 119 Query: 119 KLFVGHVRRFDKRWIQIKDIIKSRNI-LPMQIRKIEVQHLPFPADYWYWDESKSGGVIVD 177 VG +RRFD + K I + I P+ + PA++ SGG+ +D Sbjct: 120 ICQVGFMRRFDPAYADAKRRIDAGEIGKPIYYKGFTRDQGAPPAEF----IKHSGGIFID 175 Query: 178 LGVHVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTH-DHVVMFIKFEGGKTGIGEVSWS 236 +H D R+ +E V G+ + D + +I+F+ G G E S + Sbjct: 176 CSIHDYDIARYLLGAEITSVSGHGRILNNPFMEQYGDVDQALTYIEFDSGAAGDVEASRT 235 Query: 237 YPMPPKYGVFYHHL--DIIGKNGRI---RYTPMDTPVVGVVKSSFE-MPRFSPMLSTFPQ 290 P YG H + ++IG G I ++ SSF+ +P F + F + Sbjct: 236 SP----YG---HDIRAEVIGTEGSIFIGTLRHQHVTILSAKGSSFDIIPDFQ---TRFHE 285 Query: 291 AFEAELRHFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKVEV 340 A+ EL+HF EC+++ P+VT DA I L++ A S + G PV+++V Sbjct: 286 AYCLELQHFAECVRNGKTPIVTDIDATINLEVGIAATNSFRNGMPVQLDV 335 >pir||E71201 probable glucose-fructose oxidoreductase - Pyrococcus horikoshii >gi|3258321|dbj|BAA31004.1| (AP000007) 335aa long hypothetical glucose-fructose oxidoreductase [Pyrococcus horikoshii] Length = 335 Score = 112 bits (278), Expect = 5e-24 Identities = 97/348 (27%), Positives = 166/348 (46%), Gaps = 40/348 (11%) Query: 15 IFNLAHKPALKSLRTI-----AKVVAVMD--IDEEAARKAGKELNAKVFTSLDEFL-EQD 66 I + AH AL+ TI AK+VA+ + A+ K+ AK + + ++ L ++ Sbjct: 6 IISYAHPHALRYASTIRASRRAKLVAISGDGANSALAKVEAKKYGAKFYQNYEQLLKDKS 65 Query: 67 MNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVGHVR 126 + V I TY H E+AI A + GK +++EKPIALT+E+ ++++K A +KL V Sbjct: 66 VEAVYIAIETYRHKEVAIRAAEEGKDILLEKPIALTLEDGKEIVKAARKAGVKLMVPFNP 125 Query: 127 RFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPA------DYWYWDESKS-GGVIVDLG 179 RF + + K++I+S I ++ +++ P W++D KS GG +D Sbjct: 126 RFTQPLQKAKEMIESGEIGKLEYIYTISEYVKPPMFLEGIDTSWFFDIRKSGGGGFMDTA 185 Query: 180 VHVTDFLRWFFESEPIEVFA-VGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWSYP 238 H D L W ESEP++V+A +G I G + D I+F+ + W+ P Sbjct: 186 PHGIDSLFWLTESEPVKVYADIGSKIWG----FEVDDIGTALIEFKNNVIALLTAGWANP 241 Query: 239 MPPKYGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPRFSPMLSTFPQAF------ 292 YG+ + I+G +G + +++++ P F+ + F Sbjct: 242 KGYPYGLEMKYY-IVGDDGFLD-----------IRTAY--PDFTVYQEKTEKIFWERADV 287 Query: 293 EAELRHFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKVEV 340 E + F + I+ EP +T +DAL L + A ES K G+ VK+ + Sbjct: 288 EGIINAFIDAIQQDREPPITGEDALKNLALVLAAYESSKTGKVVKINL 335 >gb|AAK43115.1| Dehydrogenase, putative [Sulfolobus solfataricus] Length = 319 Score = 107 bits (265), Expect = 2e-22 Identities = 93/331 (28%), Positives = 161/331 (48%), Gaps = 38/331 (11%) Query: 5 LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAK-VFTSLDEFL 63 +K+ ++GC F H A++++ I V +EE AR+ KE NA+ FT ++ + Sbjct: 1 MKIAVVGCDG-FGKVHLRAMRNISGIEYYV--FSRNEEKARECMKEFNAEGYFTRYEDVI 57 Query: 64 EQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVG 123 + ++++V++L H + + A+KAGKH+++EKPIA T+EEA +I +++ + K V Sbjct: 58 KSNVDIVDLLVSHDQHYPMGVMAMKAGKHLMLEKPIARTIEEAMGLINTSKDTKRKFMVL 117 Query: 124 HVRRFDKRWIQIKDII-KSRNILPMQIRKIEVQHLPFPADYWYWDESKSGGVIVDLGVHV 182 F+ + K+++ + N+ + +R I HL P + E GG ++D GVH Sbjct: 118 EQFYFESSVRKAKELLPRLGNLSLIIVRSI---HLYQPKGWRREKEKMGGGALIDGGVHF 174 Query: 183 TD-FLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWSYPMPP 241 D L E E + GK G + D + ++F G G+ SW+ P PP Sbjct: 175 IDTLLNLGGEYESVR-GVCGKYFSG----IEGEDLTLATLRFRKGHLGLLMYSWTTPNPP 229 Query: 242 KYGVFYHHLDIIGKNGRIRYTPMDTPVVGVV-----------KSSFEMPRFSPMLSTFPQ 290 K F +I G+NG I P +T V+G + E+ + +P+ Sbjct: 230 KVPAF----EIYGENGSIIEDP-NTRVMGKAYGDLILNVDGKEERIEVEKVNPI------ 278 Query: 291 AFEAELRHFFECIKSSCEPVVTAQDALIALK 321 E E+R F + +K++ E + + AL LK Sbjct: 279 --EEEIRGFVKAVKNNTEVPMPPEIALRDLK 307 >gb|AAK43149.1| Dehydrogenase, putative [Sulfolobus solfataricus] Length = 371 Score = 106 bits (261), Expect = 5e-22 Identities = 96/361 (26%), Positives = 166/361 (45%), Gaps = 30/361 (8%) Query: 1 MPEKLKVGIIGCGNIFNLAHKPALKSLRT---IAKVVAVMDIDEEAARKAGKELNAKVFT 57 M +++ V ++G G+I H ALK L K+VAV+D + A K G E +T Sbjct: 16 MSKRIGVAVVGLGSI-GKTHVKALKDLEKETEFVKLVAVVDQIKAIAEKIGSEYGTPYYT 74 Query: 58 SLDEFLEQ-DMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQ 116 ++DE L +++V+ I TP+Y HA AI A++ GKHVIVEKP+A T+ A +M+ AE Sbjct: 75 TIDEVLRNSEVDVISIATPSYLHAPQAILAIEYGKHVIVEKPMATTLAGAREMVSRAERN 134 Query: 117 ELKLFVGHVRRFDKRWIQIK-DIIKSRNILPMQIRKIEVQHLPFPADYWYWDE------- 168 E+KL V R+ ++K DI+K + + + + E++ Y+ DE Sbjct: 135 EVKLGVIFQERYAPDIRRLKNDILK--ELGRIYLIESELKWYRDMKGYYKRDEIARSWRG 192 Query: 169 ---SKSGGVIVDLGVHVTDFLRWF-FESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFE 224 ++ GGV+ + G+H D + W E E + F G + D V ++++ Sbjct: 193 MWNTEGGGVMTNQGIHTIDLMIWLNGEVEEVSGFVDNLTHDG----IEVEDTAVAIMRYK 248 Query: 225 GGKTGIGEVSWSYPMPPKYGVFYHHLDIIGKNGRIRYTPMDTPVV---GVVKSSFEMPRF 281 G +G +S + M P Y + + G NG + T V G ++ S + Sbjct: 249 NG--ALGTISQTVSMKPT-TYQYRKIRVNGSNGFVEITDGSLSTVAIEGKIEESKSSVEY 305 Query: 282 SPMLSTFPQAFEAE-LRHFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKVEV 340 P E LR F + + + ++ + +L++ + S + VK+ + Sbjct: 306 KKETIAQPGNLHKELLRDFLRALSEDNDFPINGKEGMKSLEVIKAVYLSSVNRQVVKLPL 365 Query: 341 N 341 + Sbjct: 366 D 366 >gb|AAC01706.1| (AF040570) unknown [Amycolatopsis mediterranei] Length = 342 Score = 104 bits (256), Expect = 2e-21 Identities = 90/343 (26%), Positives = 148/343 (42%), Gaps = 28/343 (8%) Query: 4 KLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFL 63 +L+V +IG G I L H A +V + D+ +R+ E AK SL+E L Sbjct: 18 QLEVALIGAGLIARL-HLEAWLGAGAAVRVYS----DDGRSRELAAEFGAKAAGSLEEAL 72 Query: 64 EQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVG 123 + + V+I TPT +H E+A+ A+ AG V+ EKP+A + EEAE+++ AE ++L+ Sbjct: 73 D-GADAVDICTPTASHHEIALTAIAAGVGVVCEKPLAASAEEAEEIVTAAERAGVRLYAA 131 Query: 124 HVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPADYWYWDESKSGGVIVDLGVHVT 183 H RF + ++ +++ S + + + P + ++SGG++ D +H Sbjct: 132 HDVRFAAPYARLHELVASGRLGEGALGRFSFSAY-HPRPWTGHASARSGGILTDQLLHGA 190 Query: 184 DFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHV---VMFIKFEGGKTGIGEVSWSYPMP 240 D W F +V V +G+ V + G W+ Sbjct: 191 DLAHWVFG----DVVRVHACYQGDIATPAPEGAVATGTAVLTHASGAISQVVSRWTATPR 246 Query: 241 PKYGVFYHHLDIIGKNGRIRYT---PMDTPVVGVVKSSFEMPRFSPMLSTFPQAFEAELR 297 P V +H + G G + Y P + VV +F P F+ E+R Sbjct: 247 PPVRVAFH---VSGTGGSVSYDSEWPQEVRVVDGGAGNFAYGG--------PSVFDTEMR 295 Query: 298 HFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKVEV 340 F EP + A+DAL A++I A ES G V++ V Sbjct: 296 EFATAFAGGPEPRIGAKDALAAVRIIHAAAESAWTGRAVELPV 338 >gb|AAK43117.1| Dehydrogenase, putative [Sulfolobus solfataricus] Length = 355 Score = 104 bits (256), Expect = 2e-21 Identities = 96/359 (26%), Positives = 166/359 (45%), Gaps = 27/359 (7%) Query: 4 KLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFL 63 K++ GIIG G H L L+ ++VAV D+ +E + + N K + E + Sbjct: 2 KIRYGIIGVGGHGKNRHLIPLIKLKNKVEIVAVADVKKERCEEVSSQFNIKCYLDYMEMV 61 Query: 64 EQD-MNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFV 122 E++ +N V I+TPT H+ +AI L G +V+V+KP+ +EE ++++ A N+ LKL V Sbjct: 62 EKESLNAVSIVTPTGLHSRIAINVLNKGVNVLVDKPLGSNLEEVKEVVNTARNKGLKLMV 121 Query: 123 GHVRRFDKRWIQIKDIIKSRNI-LPMQIRKIEVQHLPFPADYWYWDESKSG--GVIVDLG 179 G+ RF K+II + + P V+ P + D++ SG G ++D+G Sbjct: 122 GYWSRFSPALQYGKEIIHNGLLGEPYVAYGYLVRRRGIPGIPTFIDKTLSGGRGALLDIG 181 Query: 180 VHVTDFLRWFFE-SEPIEVFAVGKA------IRGEARVN---------KTHDHVVMFIKF 223 ++ D L + +PI V +GK ++ E + N D+ V +K Sbjct: 182 CYLIDNLLSLLKFRKPISV--MGKVYTKFGNVKEEVKFNWGSWDPENFSLDDYAVGLVKL 239 Query: 224 EGGKTGIGEVSWSYPMPPKYGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFE--MPRF 281 EG + I EV WS + Y + I+G G I + + V S E + Sbjct: 240 EGDVSLILEVGWSANVSHVEEKSY--VRILGDKGGIEGSGHEAIVDISFHSRTENFLTDT 297 Query: 282 SPMLSTFPQAFEAELRHFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKVEV 340 P+L FE + F + I + EP +T ++++ I + +S + + VK+ + Sbjct: 298 KPVLRKVDPYFEM-INAFVDSILTDREPPITGEESVTLHSIIDGIYKSSTEDKEVKISL 355 >emb|CAB88961.1| (AL353864) putative oxidoreductase. [Streptomyces coelicolor A3(2)] Length = 358 Score = 103 bits (254), Expect = 3e-21 Identities = 93/338 (27%), Positives = 151/338 (44%), Gaps = 14/338 (4%) Query: 5 LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFLE 64 +++GI+G G I H L L ++ +V V D +AA+ A + A+V S + Sbjct: 25 MRIGILGLGRI-GAFHAETLAGLDSVGSLV-VADPFADAAKAAAERFGAEVADSPEAVFA 82 Query: 65 QDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVGH 124 ++ V I T H +L + A++AG V EKP+A T+ E +++K +++ + +G+ Sbjct: 83 AGVDGVVIAAATDAHPDLILAAVEAGVPVFCEKPVARTMAEGVEVLKALAGRDVPVQIGY 142 Query: 125 VRRFDKRWIQIKDIIKSRNILPMQ-IRKIEVQHLPFPADYWYWDESKSGGVIVDLGVHVT 183 RRFD + + ++S + P+ +R + P PA Y + SGG+ D VH Sbjct: 143 QRRFDTGFAAARAAVRSGELGPLHTVRSTTLDPAPPPAAY----VAASGGIFRDCSVHDF 198 Query: 184 DFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWSYPMPPKY 243 D +RW E EV+AVG RG + + D + VS S Y Sbjct: 199 DSIRWVTGREVGEVYAVG-GNRGADYIREAGDADTTGAVLTLDDGTVAVVSNSRHNARGY 257 Query: 244 GVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPRFSP---MLSTFPQAFEAELRHFF 300 V ++I G + I D + V+ P +P + F A+ AEL F Sbjct: 258 DV---RMEIHGFDDSIAVGLEDRLPLRSVEPGVTFPAGTPHDFFMDRFTAAYRAELTAFT 314 Query: 301 ECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKV 338 E + + T +DAL A IAE S+ + PV + Sbjct: 315 EVVAGARPSPCTVEDALEAGWIAEACTLSLHEHRPVTI 352 >gb|AAC31183.1| (AF076240) putative NADH-inositol dehydrogenase MocA [Rhizobium leguminosarum bv. viciae] Length = 306 Score = 97.5 bits (239), Expect = 2e-19 Identities = 89/330 (26%), Positives = 142/330 (42%), Gaps = 35/330 (10%) Query: 4 KLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFL 63 + ++G+IG G + + + A +SL + +V AV++ A R A + K + + DE + Sbjct: 3 EFRLGLIGAGRMGQVHLRAASESL--LVEVTAVVE-PVAATRLALERSGIKTYKTADEMI 59 Query: 64 EQ-DMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFV 122 + +++ V I TP+ TH E G ++ EKP +T EEA K + AE ++ L + Sbjct: 60 DAGEIDGVLIATPSKTHVENITNIAARGLPILCEKPCGVTAEEARKAAEAAEQFKVHLQI 119 Query: 123 GHVRRFDKRWIQIKDIIKSRNI-LPMQIRKIEVQHLPFPADYWYWDESKSGGVIVDLGVH 181 G+ RRF +++ I+S + P I + P A + + GG ++D+GVH Sbjct: 120 GYWRRFVPELEKLRQNIRSGLLGEPYLISCFQWDETPPAASF----RATGGGALIDMGVH 175 Query: 182 VTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWSYPMPP 241 D +RW EP +V D V + GG G+G VS PP Sbjct: 176 EFDQMRWLTGQEPSNFRVAASKTTFAGKVEGDPDAVQLLCDLSGG--GVGLVSLGRRFPP 233 Query: 242 KYGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPRF---SPMLSTFPQAFEAELRH 298 + + G +G FE RF + F A ++L Sbjct: 234 GDACW---AQVFGTSG------------------FEEVRFFWPPNGEAVFLNALRSQLED 272 Query: 299 FFECIKSSCEPVVTAQDALIALKIAEKAKE 328 F + + TAQDA+ AL IAE A E Sbjct: 273 FVQAARGGASQGATAQDAVTALAIAEAATE 302 >sp|O68965|MI2D_RHIME MYO-INOSITOL 2-DEHYDROGENASE >gi|3088561|gb|AAC70005.1| (AF059313) myo-inositol dehydrogenase [Sinorhizobium meliloti] Length = 330 Score = 94.8 bits (232), Expect = 1e-18 Identities = 86/339 (25%), Positives = 143/339 (41%), Gaps = 17/339 (5%) Query: 5 LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFLE 64 ++ G++G G I + K S A++VAV D AA +V T Sbjct: 3 VRFGLLGAGRIGKVHAKAV--SGNADARLVAVADAFPAAAEAIAGAYGCEVRTIDAIEAA 60 Query: 65 QDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVGH 124 D++ V I TPT THA+L +AGK + EKPI L E +K + + KL VG Sbjct: 61 ADIDAVVICTPTDTHADLIERFARAGKAIFCEKPIDLDAERVRACLKVVSDTKAKLMVGF 120 Query: 125 VRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPF-PADYWYWDESKSGGVIVDLGVHVT 183 RRFD ++ ++ I I +++ I + P DY +SGG+ D+ +H Sbjct: 121 NRRFDPHFMAVRKAIDDGRIGEVEMVTITSRDPSAPPVDY----IKRSGGIFRDMTIHDF 176 Query: 184 DFLRWFFESEPIEVFAVGKAIRGEARVNK-THDHVVMFIKFEGGKTGIGEVSWSYPMPPK 242 D R+ EP+ V A + +A + +D V + ++ GK I S Sbjct: 177 DMARFLLGEEPVSVTATAAVLIDKAIGDAGDYDSVSVILQTASGKQAIIANS----RRAT 232 Query: 243 YGVFYHHLDIIGKNGRIRYTPMDTPV---VGVVKSSFEMPRFSPMLSTFPQAFEAELRHF 299 YG + +++ G G + PV + P ++ + +A+ E+ F Sbjct: 233 YG-YDQRIEVHGSKGAVA-AENQRPVSIEIATGDGYTRPPLHDFFMTRYTEAYANEIESF 290 Query: 300 FECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKV 338 I+ E + D L AL +A+ A S+ + + + Sbjct: 291 IAAIEKGAEIAPSGNDGLAALALADAAVRSVAEKRQISI 329 >emb|CAB60174.1| (AL132824) putative dehydrogenase [Streptomyces coelicolor] Length = 337 Score = 93.6 bits (229), Expect = 3e-18 Identities = 89/341 (26%), Positives = 150/341 (43%), Gaps = 20/341 (5%) Query: 5 LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFLE 64 +++G+IG G I H L R + ++ + D D A++ L +DE + Sbjct: 1 MRIGVIGTGRI-GTVHANTLSRHRDVGSLI-LTDADIARAQELAHRLGETAAPGVDEIFQ 58 Query: 65 QDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVGH 124 ++ V I T T HAEL A ++G V EKPIAL + + I E E L +G Sbjct: 59 WGVDAVVITTATPAHAELIGRAARSGLPVFCEKPIALDLPGTLQAIAEVEAAGTVLQMGF 118 Query: 125 VRRFDKRWIQIKDIIKSRNILPMQ-IRKIEVQHLPFPADYWYWDESKSGGVIVDLGVHVT 183 RRFD + ++ ++S + + +R + P PADY +SGG+ D +H Sbjct: 119 QRRFDTGYTGAREAVRSGRLGRLHTVRAVTSDQTPPPADYL----PQSGGLYRDTLIHDF 174 Query: 184 DFLRWFFESEPIEVFAVGK-AIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWSYPMPPK 242 D LRW E ++V+A G A R D + + + G + Sbjct: 175 DVLRWVTGREVVDVYAAGSDAGPPMFRAADDVDTGAVLLTLDDGTLATATAA------RL 228 Query: 243 YGVFYH-HLDIIGKNGRIRYTPMD-TPVVGVVKS---SFEMPRFSPMLSTFPQAFEAELR 297 G Y +++ G+ +I D TP+ + + + P ++ + F A+EAEL Sbjct: 229 NGAGYDVRMELAGELDQIVVGLDDRTPIASTEPTGPPAADKP-WTGFVERFGPAYEAELT 287 Query: 298 HFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKV 338 F + ++ ++AL AL+IAE S ++ PV++ Sbjct: 288 TFVQVVRGERANPCDGREALQALRIAEACDVSRRERRPVRL 328 >dbj|BAB05884.1| (AP001514) unknown conserved protein [Bacillus halodurans] Length = 348 Score = 93.6 bits (229), Expect = 3e-18 Identities = 83/352 (23%), Positives = 159/352 (44%), Gaps = 25/352 (7%) Query: 3 EKLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAK-VFTSLDE 61 +KL+VGIIG G I H P+ SL+ ++VA+ D+ + A+ A ++ + V+ Sbjct: 4 KKLRVGIIGAGGIARTVHIPSYLSLKDQVELVAITDVQPKHAQAAAEQFSIPYVYNDASR 63 Query: 62 FLEQ-DMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKL 120 +++ +++ V I TP H EL IEAL AG HV+ EKP A+TVE+A++M A+ L Sbjct: 64 MMQEVELDAVSICTPNAFHRELTIEALHAGCHVLCEKPPAITVEDAKQMEAAAKETGNLL 123 Query: 121 FVGHVRRFDKRWIQIKDII---KSRNILPMQIRKIEVQHLPFPADYWYWDESKSGGVIVD 177 G R +K + + I ++++ I + +P + E + GG ++D Sbjct: 124 TYGFHYRHSPEVETLKRFVDEGELGEIYHVRVQAIRRRGIPGWGVFTN-KELQGGGPLID 182 Query: 178 LGVHVTDFLRWFFE-SEPIEVFA---------VGKAIRGEARVNK--THDHVVMFIKFEG 225 +GVH+ D + EP + G + GE + D V I F+ Sbjct: 183 IGVHMLDTALYVMGFPEPATILGQTHRKIGTKEGVGLLGEWNWQQFSIEDMAVGMITFKN 242 Query: 226 GKTGIGEVSWSYPMPPKYGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPRFSPML 285 G + E +++ + + + ++ G G P+ + + +P+ Sbjct: 243 GASLTIETAFAANVKEQ---DHMNVSFFGDKGGADLFPLSI----YQEKHRTLLDITPVY 295 Query: 286 STFPQAFEAELRHFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVK 337 E E++HF +C +P+ T + ++ ++ + +S + G+ ++ Sbjct: 296 LPTYNHHEREIKHFVDCCFRLEQPLATPEQGIVIQRLIQGLYQSAESGKAIQ 347 >pir||S76068 hypothetical protein - Synechocystis sp. (strain PCC 6803) >gi|1001423|dbj|BAA10046.1| (D63999) hypothetical protein [Synechocystis sp.] Length = 364 Score = 93.2 bits (228), Expect = 4e-18 Identities = 77/334 (23%), Positives = 141/334 (42%), Gaps = 27/334 (8%) Query: 3 EKLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEF 62 + +++G+IG GN+ H + SL + V + D++ E + F E Sbjct: 22 QPIRIGVIGVGNMGQ--HHTRVLSLMKDVEFVGIADVNVERGLDTASKYRVHFFEDYQEM 79 Query: 63 LEQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFV 122 L ++ V + PT H ++ + L+ H ++EKPIA ++ EAE ++ A + L V Sbjct: 80 LPH-VDAVCVAVPTRLHHDVGMNCLQNNVHTLIEKPIAASIAEAESLVNAAADANCILQV 138 Query: 123 GHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPADYWYWDESKSGGVIVDLGVHV 182 GH+ RF+ ++++ I+K+ +L ++ ++ Y + V++DL +H Sbjct: 139 GHIERFNPAFLELTKILKTEELLAIEAHRMSP----------YSQRANDVSVVLDLMIHD 188 Query: 183 TDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWSYPMPPK 242 D L SE +++ A G G + D+V + F G + ++ S K Sbjct: 189 IDLLLELVGSEVVKLSASGSRASGSGYL----DYVTATLGFSSGI--VATLTASKVTHRK 242 Query: 243 YGVFYHH-------LDIIGKNGRI-RYTPMDTPVVGVVKSSFEMPRFSPMLSTFPQAFEA 294 H D + I R T D + + ++ + A Sbjct: 243 IRSIAAHCKNSLTEADFLNNEILIHRQTTADWSADYGQVLYRQDGLIEKVYTSNIEPLHA 302 Query: 295 ELRHFFECIKSSCEPVVTAQDALIALKIAEKAKE 328 EL HF C++ +P V + AL ALK+A +E Sbjct: 303 ELEHFIHCVRGGDQPSVGGEQALKALKLASLIEE 336 >pir||A69834 conserved hypothetical protein yhjJ - Bacillus subtilis >gi|2226182|emb|CAA74472.1| (Y14081) hypothetical protein [Bacillus subtilis] >gi|2633389|emb|CAB12893.1| (Z99109) similar to hypothetical proteins [Bacillus subtilis] Length = 350 Score = 93.2 bits (228), Expect = 4e-18 Identities = 63/197 (31%), Positives = 107/197 (53%), Gaps = 16/197 (8%) Query: 6 KVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFLEQ 65 K+GIIG G I AH AL +++ A++V V DI+++ A K K F ++DE ++ Sbjct: 3 KIGIIGAGGIAR-AHATALSTIKN-AELVGVYDINQQNAESFVKTFGGKSFENVDELIDA 60 Query: 66 DMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVGHV 125 ++ + +P + H E A++AL KHV+ EKP+A+++EEA M AE ++ +G Sbjct: 61 SEGLI-VASPNFCHKEHALQALGKHKHVLCEKPMAISLEEASIMKDTAERLSVRASMG-- 117 Query: 126 RRFDKRWIQIKDIIKS-------RNILPMQIRKIEVQHLPFPADYWYWD--ESKSGGVIV 176 F+ R++ +I+KS NIL +++ + L W D K+ G + Sbjct: 118 --FNYRYLSYVNILKSLIINNELGNILSIKVHFKKNSALRRKKFTWRDDANSKKTSGSLG 175 Query: 177 DLGVHVTDFLRWFFESE 193 DLG+H+ D + + FES+ Sbjct: 176 DLGIHLIDMVWYLFESD 192 >dbj|BAB06035.1| (AP001515) myo-inositol 2-dehydrogenase [Bacillus halodurans] Length = 348 Score = 90.1 bits (220), Expect = 3e-17 Identities = 95/337 (28%), Positives = 156/337 (46%), Gaps = 23/337 (6%) Query: 5 LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKE--LNAKVFTSLDEF 62 L+ G+IG G I H +++ + K+VAV D+++EAA++ + L A V+ D Sbjct: 3 LRFGVIGTGAI-GREHMKRIENKLSGGKIVAVTDMNQEAAKQVVTQMKLEADVYPD-DRS 60 Query: 63 LEQDMNVVEILTPTY--THAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKL 120 L NV +L ++ H + A++AGK+V VEKP+A T E K+IK N +L Sbjct: 61 LVAADNVDAVLVTSWGPAHEANVLAAIEAGKYVFVEKPLATTAEGCMKIIKAEMNHGKRL 120 Query: 121 F-VGHVRRFDKRWIQIKDIIKSRNI-LPMQIRKIEVQHLPFPADYWYWDESKSGGVIVDL 178 VG +RR+DK ++Q+K I I P+ +R H Y D+ I D Sbjct: 121 VQVGFMRRYDKGYVQLKKAIDDHFIGEPLMVR---CAHRNPEVGESYIDDM----AIHDT 173 Query: 179 GVHVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWSYP 238 +H D L W + E E +V + + + D V+ ++ +GG EV Sbjct: 174 LIHEIDVLHWLIDDE-YESVSVSFPKKTKHALPHLRDPRVVTLETKGGVLITAEVF---- 228 Query: 239 MPPKYGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPRFSPMLSTFPQAFEAELRH 298 + KYG + ++I + G I P + +++ F +A++ EL+H Sbjct: 229 VNCKYG-YDIQCEVIREEG-IASLPEVDSISFRKRATLGTNILMDWKQRFIEAYDVELQH 286 Query: 299 FFECIKSSCEPV-VTAQDALIALKIAEKAKESIKKGE 334 F + IK S EP A D +A A+ A ++ G+ Sbjct: 287 FIDSIKQSGEPSGPNAWDGYVAAITADAALKASNSGQ 323 >sp|P26935|MI2D_BACSU MYO-INOSITOL 2-DEHYDROGENASE >gi|80338|pir||JH0511 myo-inositol 2-dehydrogenase (EC 1.1.1.18) iolG - Bacillus subtilis >gi|143086|gb|AAA22543.1| (M76431) inositol dehydrogenase [Bacillus subtilis] >gi|709987|dbj|BAA03296.1| (D14399) myo-inositol dehydrogenase [Bacillus subtilis] >gi|2636516|emb|CAB16006.1| (Z99124) myo-inositol 2-dehydrogenase [Bacillus subtilis] Length = 344 Score = 89.7 bits (219), Expect = 4e-17 Identities = 91/343 (26%), Positives = 165/343 (47%), Gaps = 23/343 (6%) Query: 5 LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKE--LNAKVFTSLDEF 62 L++G+IG G I H + + + A++VAV D+++EAA+K ++ LNA V+ + D+ Sbjct: 3 LRIGVIGTGAI-GKEHINRITNKLSGAEIVAVTDVNQEAAQKVVEQYQLNATVYPN-DDS 60 Query: 63 LEQDMNVVEILTPTY--THAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKL 120 L D NV +L ++ H ++A+KA K+V EKP+A T E ++++E +L Sbjct: 61 LLADENVDAVLVTSWGPAHESSVLKAIKAQKYVFCEKPLATTAEGCMRIVEEEIKVGKRL 120 Query: 121 F-VGHVRRFDKRWIQIKDIIKSR-NILPMQIRKIEVQHLPFPADYWYWDESKSGGVIVDL 178 VG +RR+D ++Q+K+ + + N P+ I P D + D + +VD Sbjct: 121 VQVGFMRRYDSGYVQLKEALDNHVNGEPLMIHC--AHRNPTVGDNYTTDMA-----VVDT 173 Query: 179 GVHVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWSYP 238 VH D L W ++ E V + + + D ++ I+ +GG E+ Sbjct: 174 LVHEIDVLHWLV-NDDYESVQVIYPKKSKNALPHLKDPQIVVIETKGGIVINAEIY---- 228 Query: 239 MPPKYGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPRFSPMLSTFPQAFEAELRH 298 + KYG + +I+G++G I+ P + + + F F A++ E++ Sbjct: 229 VNCKYG-YDIQCEIVGEDGIIK-LPEPSSISLRKEGRFSTDILMDWQRRFVAAYDVEIQD 286 Query: 299 FFECIKSSCE-PVVTAQDALIALKIAEKAKESIKKGEPVKVEV 340 F + I+ E TA D IA + ++ + G+ KVE+ Sbjct: 287 FIDSIQKKGEVSGPTAWDGYIAAVTTDACVKAQESGQKEKVEL 329 >gb|AAK43113.1| Dehydrogenase, putative [Sulfolobus solfataricus] Length = 363 Score = 88.9 bits (217), Expect = 8e-17 Identities = 92/360 (25%), Positives = 152/360 (41%), Gaps = 36/360 (10%) Query: 5 LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFLE 64 +K+GI+G G AH PAL L KV DIDE+ + ++ K + E L Sbjct: 4 MKLGIVGLGGWVTGAHIPALTDLGI--KVDYCADIDEKRVKDLSQKTGCKGYLDYKEMLR 61 Query: 65 -QDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVG 123 ++ ++V + P HA +A++A+ +V VEKP+A + +EA +++ + + L VG Sbjct: 62 NENPDLVLVAVPHSLHAIIALDAINNDANVYVEKPMATSFQEALTLVEASRKRNKILVVG 121 Query: 124 HVRRFDKRWIQIKDIIKS---RNILPMQIRKIEVQHLPFPADYWYWDESKSGGVIVDLGV 180 H RF+ + K +I+ I M+ I + +P + D +K GG + D+G Sbjct: 122 HENRFNPAMLIAKKLIRGGEVGKIYHMRGFYIRQRGIPTSPTFIKKDLAK-GGAVFDIGT 180 Query: 181 HVTDFLRWFFESEPIEVFAVGKAIRGEARVN----------------KTHDHVVMFIKFE 224 H+ D L F P GK + + D F+K Sbjct: 181 HIIDLL-LFLSDFPTPKSVTGKTYNAFSEDKTKFSAYPSPNLPNFKVEVEDFGSAFLKLG 239 Query: 225 GGKTGIGEVSW-SYPMPPKYGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKS-SFEMPRFS 282 + EVSW SY K V I+G NG I +D V+ +++ E+ S Sbjct: 240 DEISAYVEVSWASYIKENKMEVV-----ILGDNGGIH---IDNGVLNFMRNIEDELFISS 291 Query: 283 PMLSTFPQAFEAELRHFFECIKSSCE--PVVTAQDALIALKIAEKAKESIKKGEPVKVEV 340 P+ + R E I P+ +A+ I + I E +S +G VK+++ Sbjct: 292 PLTQQKGSVYREVWRTVMESISKGFPEYPLCSAEQGAIGVAILESIYKSALEGREVKIDI 351 >emb|CAC11912.1| (AL445065) hypothetical protein [Thermoplasma acidophilum] Length = 322 Score = 88.2 bits (215), Expect = 1e-16 Identities = 71/260 (27%), Positives = 125/260 (47%), Gaps = 21/260 (8%) Query: 5 LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAK-VFTSLDEFL 63 + V +IG GN F H ++ R + +V D + + ++ + ++ + L Sbjct: 6 MSVLLIG-GNGFAKVHA---ETYRRLGIEFSVYDRNPQVLEMYRRDYGVRETYSDMAAAL 61 Query: 64 EQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVG 123 + D + V+I+ P H E+A++A++ GKHV+VEKP+ ++EA K+I +A+ + LK V Sbjct: 62 DADNDAVDIVLPHNLHYEVAMKAIEKGKHVLVEKPVTGRIDEAVKIINQAKKKRLKFMVA 121 Query: 124 HVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPADYWYWDESK-SGGVIVDLGVHV 182 FD + + +I++S I ++ + Q + A W +++ GG ++D GVH Sbjct: 122 EQFYFDPSFRKALEIVQSGKIGDVRTVIVRDQQ-RYDAPGWRSRKNEMMGGSLIDGGVHF 180 Query: 183 TDFLRWF---FESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWSYPM 239 + F ++S + G +I GE D+ FE GI SWSY Sbjct: 181 LEIFLDFGGQWKSISAHNYKGGTSIEGE-------DNTAALFTFENDVHGIFYYSWSYVE 233 Query: 240 PPKYGVFYHHLDIIGKNGRI 259 PPK F ++IG G + Sbjct: 234 PPKLPAF----EVIGTEGSV 249 >pir||A82502 oxidoreductase, Gfo/Idh/MocA family VCA0099 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9657485|gb|AAF96013.1| (AE004352) oxidoreductase, Gfo/Idh/MocA family [Vibrio cholerae] Length = 346 Score = 87.8 bits (214), Expect = 2e-16 Identities = 85/356 (23%), Positives = 163/356 (44%), Gaps = 39/356 (10%) Query: 5 LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFL- 63 LKVG+IG G H P + +L ++ + A+ ++ ++ ++ F S + Sbjct: 6 LKVGVIGYGYSAKTFHLPFIDTLESLT-LSAISSSQQQVVQEDWPQI--AYFDSAQRLIT 62 Query: 64 EQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVG 123 E D+++V I P H LA AL+ GKHVIVEKP +E+ +I+ A Q L L V Sbjct: 63 ESDVDLVIITAPNNVHFPLAKLALEHGKHVIVEKPFVTQIEQGRTLIELARQQGLLLSVF 122 Query: 124 HVRRFDKRWIQIKDIIKSRNILPMQIRKIEV-QHLPFPADYWYWDESKSGGVIVDLGVHV 182 H RR+D ++ +K +I+ + +++ + ++ P W + GG++ DL H+ Sbjct: 123 HNRRWDGDFLTVKKLIEQGQLGDVKVFESHFDRYRPVVRQRWREQAQEGGGILFDLAPHL 182 Query: 183 TDFLRWFFESEPIEVFAVGKAIRGEARVNK----THDHVVMFIKFEGGKTGIGEVSWSYP 238 D + + +F + +++ + R+ + T D+ + + + + +S Sbjct: 183 LD--------QALVLFGLPQSLSADCRMMRPDATTLDYFDLQLYYPQHVVRLHANLYS-- 232 Query: 239 MPPKYGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPRFS-PMLSTFPQAFEAE-- 295 P+ V Y L +GK + P + + + + P++S M + + AE Sbjct: 233 --PEPNVRYQVLGSLGKYVKYGLDPQEDRLKAGERPTH--PQWSQEMPEQYGILYHAEGN 288 Query: 296 ---------LRHFF----ECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKV 338 +H+F E I++ V+A+ AL ++++ E A ES KG+ + V Sbjct: 289 ENVITELGGYQHYFTQVVEAIRNGASNPVSAESALQSIQLIELALESSAKGQRLAV 344 >sp|P49307|MOCA_RHIME RHIZOPINE CATABOLISM PROTEIN MOCA >gi|2120810|pir||S51572 mocA protein - Rhizobium meliloti >gi|468762|emb|CAA55269.1| (X78503) mocA [Sinorhizobium meliloti] Length = 317 Score = 86.6 bits (211), Expect = 4e-16 Identities = 81/339 (23%), Positives = 140/339 (40%), Gaps = 45/339 (13%) Query: 4 KLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMD-IDEEAARKAGKELNAKVFTSLDEF 62 + ++G++G G + + + A +S ++ ++ AV D I AG + K + + + Sbjct: 3 RFRLGLVGAGRMGQVHVRAAAES--SLVEIAAVADPIAASRLNLAGNGI--KTYETAGDM 58 Query: 63 LEQ-DMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLF 121 +E +++ V I TP+ TH + + G ++ EKP +T EEA K AE ++ L Sbjct: 59 IEAGEVDGVLIATPSNTHVDTVADIAARGLPILCEKPCGVTAEEARKAADVAERYKVHLQ 118 Query: 122 VGHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPADYWYWDE--------SKSGG 173 +G+ RRF Q++D I++ + + + + WDE + GG Sbjct: 119 IGYWRRFVPELKQLRDDIRAGLLGNLYL-----------VSCFQWDEAPPANSFRATGGG 167 Query: 174 VIVDLGVHVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEV 233 +D+GVH D +RW EP V D V + G +G+ V Sbjct: 168 AFIDMGVHEFDQMRWLTGQEPTNFRVATSKTTFAGAVKGDPDAVQLLCDLSDGSSGL--V 225 Query: 234 SWSYPMPPKYGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPRFSPMLSTFPQAFE 293 S PP + + G + G ++ F P + F A + Sbjct: 226 SLGRRFPPGDACW---TQVFGTS-------------GFAEARFFWPPDGE--AVFLNALQ 267 Query: 294 AELRHFFECIKSSCEPVVTAQDALIALKIAEKAKESIKK 332 A+L F + + TA DA+ AL IAE A E + + Sbjct: 268 AQLEDFVQAARGGAPRGATASDAVAALTIAEAATELLSR 306 >dbj|BAB05939.1| (AP001514) dehydrogenase [Bacillus halodurans] Length = 345 Score = 86.2 bits (210), Expect = 5e-16 Identities = 82/346 (23%), Positives = 151/346 (42%), Gaps = 16/346 (4%) Query: 3 EKLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKV-FTSLDE 61 + +KVG++G G + H L ++ AV + E ++A + +TS +E Sbjct: 2 KSVKVGLVGLGRL-GQQHGDNLAFRIPRCELTAVCSVVEAEVKQARERWGVPYGYTSYEE 60 Query: 62 FL-EQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKL 120 L ++++ + I +P+ H E + L+ G HV EKP+ L + E ++ + ++ Sbjct: 61 MLANEELDAIFIASPSGFHCEQIKKGLEKGFHVFCEKPLGLHLAEVREVENAVNRHKDQV 120 Query: 121 FV-GHVRRFDKRWIQIKDIIKSRNI-LPMQIRKIEVQHLPFPADYWYWDESK-SGGVIVD 177 F+ G +RR+D + K+ I I P+ IR + + + ++ SGG+ +D Sbjct: 121 FMLGFMRRYDPSYQAAKEKINRGEIGEPVLIRCYGLDPASQIDGFLAFAKANDSGGLFLD 180 Query: 178 LGVHVTDFLRWFFESEPIEVFAVGKAI-RGEARVNKTHDHVVMFIKFEGGKTGIGEVSWS 236 + +H D RW+ +E EV+A+G + R E + ++F+ G+ Sbjct: 181 MSIHDFDLARWYLGAEASEVWAIGGSYSRPEFAELGDAETGAAMVRFDNQAIGL------ 234 Query: 237 YPMPPKYGVFYH-HLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPR--FSPMLSTFPQAFE 293 + YH +IIG G IR + VV + + + F QA+ Sbjct: 235 FVAGRNCAHGYHIETEIIGTKGTIRIGSIPERNQAVVMNEHGVIHECVQGFIERFEQAYR 294 Query: 294 AELRHFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKVE 339 AE F CI +P VT +D + + K+ K+S + V+ Sbjct: 295 AEAEEFIRCILEGRKPDVTVKDGVESTKLGYACKQSFTTKTLINVQ 340 >emb|CAC12307.1| (AL445066) glucose-fructose oxidoreductase related protein [Thermoplasma acidophilum] Length = 321 Score = 86.2 bits (210), Expect = 5e-16 Identities = 82/287 (28%), Positives = 122/287 (41%), Gaps = 39/287 (13%) Query: 5 LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELN--------AKVF 56 +KV IIG N F H A L D+D E + + + KV Sbjct: 1 MKVNIIGL-NGFGKRHIEAWSKL----------DVDIEITERKAEVVRDLLSRYDIVKVN 49 Query: 57 TSLDEFLEQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQ 116 +SL+E D + +++ P H ++ +++L GKHV+VEKPIA + +A +MI+ A Sbjct: 50 SSLEEAFNSDAEIFDLVLPHNLHHDVTVKSLAMGKHVMVEKPIATDISDAREMIRTAVQN 109 Query: 117 ELKLFVGHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPADYWYWDESKS---GG 173 K V FD + K+I+ S I + I Q ++ W S GG Sbjct: 110 RRKFMVADQYYFDPSVWKAKEIMDSGKIGSVHTIIIRDQR---KYNWHGWRSQASIMGGG 166 Query: 174 VIVDLGVHVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEV 233 ++D G+H D + E I V + R A + + D V KF+ G G+ Sbjct: 167 PLIDGGIHFIDTM-LNLAGEYISVRS--NFYRSVASIEEP-DTVEAIFKFKDGSNGLFFY 222 Query: 234 SWSYPMPPKYGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPR 280 SW YP PP F +IIG +G I P S+FE P+ Sbjct: 223 SWGYPYPPSLPSF----EIIGTDGSILEDLRSKP------SNFEAPK 259 >dbj|BAB05940.1| (AP001514) unknown conserved protein [Bacillus halodurans] Length = 345 Score = 85.8 bits (209), Expect = 7e-16 Identities = 81/342 (23%), Positives = 149/342 (42%), Gaps = 19/342 (5%) Query: 5 LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFLE 64 + +G+IG G I L + S K V+ + +D + + + + F Sbjct: 4 VNIGLIGAGRIGQLHASNIISSPYMELKAVSDVQLDHLKGTEIERSVEIMTTNPDELFSN 63 Query: 65 QDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVGH 124 +D++ + I + T THA A AGKH+ EKPI+ V E + + +K VG Sbjct: 64 RDIDAIFICSSTDTHAAFIKAAALAGKHIFCEKPISFHVTETKGALNIVNEAGVKFQVGF 123 Query: 125 VRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPADYWYWDESKSGGVIVDLGVHVTD 184 RR+DK + ++++ +++ I I ++ + P + +SGG+ +D+ +H D Sbjct: 124 NRRYDKHFRRVQECVQAGAIGAPHIIRVSSRDPEAPPLSYV---ERSGGMFMDMTIHDFD 180 Query: 185 FLRWFFESEPIEVFAVGKAIRGEARVNKTH--DHVVMFIKFEGGKTGIGEVS--WSYPMP 240 +R+ SE EV +V A ++R+ + D ++ + E G + + S +Y Sbjct: 181 MVRYLSGSEVTEV-SVKAANLVDSRIGEVGDVDTAIITLMLENGAIAVIDNSRQAAYGYD 239 Query: 241 PKYGVFYHHLDIIGKNGR---IRYTPMDTPVVGVVKSSFEMPRFSPMLSTFPQAFEAELR 297 + VF + N R ++ + DT + + K F L + QA++ E+ Sbjct: 240 QRVEVFGSLGSVSADNERKTNVQISTKDTVTLDLPKHFF--------LDRYEQAYKDEVA 291 Query: 298 HFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKVE 339 F I T +D A +A AK+S + PV V+ Sbjct: 292 EFATAILEDQPLRCTGEDGYKAELLALAAKQSWLENRPVAVK 333 >pir||S70672 dehydrogenase homolog - Bordetella pertussis >gi|992971|emb|CAA62245.1| (X90711) gene referred to as bplA in Mol. Microbiol. 19:37-52(1996) [Bordetella pertussis] >gi|3451515|emb|CAA07671.1| (AJ007747) putative oxidoreductase [Bordetella bronchiseptica] >gi|1589221|prf||2210367C bplA gene [Bordetella pertussis] Length = 350 Score = 85.4 bits (208), Expect = 9e-16 Identities = 86/356 (24%), Positives = 151/356 (42%), Gaps = 49/356 (13%) Query: 4 KLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFL 63 K++ G++GCG I + H A+ A++V + D + EA + A A+ F+SL + L Sbjct: 10 KIRFGLVGCGRI-SKNHIGAIAQHGDRAELVEICDTNPEALQAAEAATGARPFSSLSDML 68 Query: 64 EQ-DMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFV 122 Q + + + + TP+ H AIE +AG+HV+ EKP+A E+ ++M+K + ++LFV Sbjct: 69 AQGNADALVLATPSGLHPWQAIEVAQAGRHVVSEKPMATRWEDGKRMVKACDEAGVRLFV 128 Query: 123 GHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPADY---------WYWDESKSGG 173 R + +K I+ + + + V P +Y W WD GG Sbjct: 129 VKQNRRNATLQLVKKAIEQGRFGRIYMVTVNV-FWTRPQEYYDAARWRGKWEWD----GG 183 Query: 174 VIVDLGVHVTDFLRWFFESEPIE-VFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTG-IG 231 ++ H D L W P+E V+A + AR + D V +++ G G I Sbjct: 184 AFMNQASHYVDLLDWLV--GPVESVYAYTATL---ARRIEAEDTGVAALRWRHGAMGSIN 238 Query: 232 EVSWSYPMPPKYGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPRFSPMLSTFPQA 291 +YP + + I+G+ G +R V GV + + +F+ + Sbjct: 239 VTMLTYPQNLEGSI-----TILGEKGTVR-------VGGVAVNRIDEWKFAEPHPDDDKI 286 Query: 292 FEAELR--------------HFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKG 333 EA + C++ CEP ++ L +L + S + G Sbjct: 287 REANYETTSVYGFGHPLYYDNVINCLRGDCEPETDGREGLQSLALLTAIYRSARDG 342 >emb|CAB02496.1| (Z80356) glucose-fructose oxidoreductase [Zymomonas mobilis] Length = 433 Score = 84.7 bits (206), Expect = 1e-15 Identities = 65/277 (23%), Positives = 122/277 (43%), Gaps = 7/277 (2%) Query: 67 MNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVGHVR 126 ++ V I+ P HAE AI A KAGKHV+ EKP+A +V + ++MI A+ KL +G+ Sbjct: 151 IDAVYIILPNSLHAEFAIRAFKAGKHVMCEKPMATSVADCQRMIDAAKAANKKLMIGYRC 210 Query: 127 RFDKRWIQIKDIIKSRNILPMQI---RKIEVQHLPFPADYW-YWDESKSGGVIVDLGVHV 182 +D +I+ + + + +V PA W E GG ++D+G++ Sbjct: 211 HYDPMNRAAVKLIRENQLGKLGMVTTDNSDVMDQNDPAQQWRLRRELAGGGSLMDIGIYG 270 Query: 183 TDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWSYPMPPK 242 + R+ EPIEV A + + R + D ++ ++F G G S+S + Sbjct: 271 LNGTRYLLGEEPIEVRAYTYSDPNDERFVEVEDRIIWQMRFRSGALSHGASSYSTTTTSR 330 Query: 243 YGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPRFSPMLSTFPQAFEAELRHFFEC 302 + V ++ Y + + + MP+F + F A+L H E Sbjct: 331 FSVQGDKAVLLMDPATGYYQNLISVQTPGHANQSMMPQF---IMPANNQFSAQLDHLAEA 387 Query: 303 IKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKVE 339 + ++ ++ + +++ + E+ + G PV + Sbjct: 388 VINNKPVRSPGEEGMQDVRLIQAIYEAARTGRPVNTD 424 >pdb|1OFG|A Chain A, Glucose-Fructose Oxidoreductase >gi|2098324|pdb|1OFG|B Chain B, Glucose-Fructose Oxidoreductase >gi|2098325|pdb|1OFG|C Chain C, Glucose-Fructose Oxidoreductase >gi|2098326|pdb|1OFG|D Chain D, Glucose-Fructose Oxidoreductase >gi|2098327|pdb|1OFG|E Chain E, Glucose-Fructose Oxidoreductase >gi|2098328|pdb|1OFG|F Chain F, Glucose-Fructose Oxidoreductase Length = 381 Score = 84.7 bits (206), Expect = 1e-15 Identities = 65/277 (23%), Positives = 122/277 (43%), Gaps = 7/277 (2%) Query: 67 MNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVGHVR 126 ++ V I+ P HAE AI A KAGKHV+ EKP+A +V + ++MI A+ KL +G+ Sbjct: 99 IDAVYIILPNSLHAEFAIRAFKAGKHVMCEKPMATSVADCQRMIDAAKAANKKLMIGYRC 158 Query: 127 RFDKRWIQIKDIIKSRNILPMQI---RKIEVQHLPFPADYW-YWDESKSGGVIVDLGVHV 182 +D +I+ + + + +V PA W E GG ++D+G++ Sbjct: 159 HYDPMNRAAVKLIRENQLGKLGMVTTDNSDVMDQNDPAQQWRLRRELAGGGSLMDIGIYG 218 Query: 183 TDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWSYPMPPK 242 + R+ EPIEV A + + R + D ++ ++F G G S+S + Sbjct: 219 LNGTRYLLGEEPIEVRAYTYSDPNDERFVEVEDRIIWQMRFRSGALSHGASSYSTTTTSR 278 Query: 243 YGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPRFSPMLSTFPQAFEAELRHFFEC 302 + V ++ Y + + + MP+F + F A+L H E Sbjct: 279 FSVQGDKAVLLMDPATGYYQNLISVQTPGHANQSMMPQF---IMPANNQFSAQLDHLAEA 335 Query: 303 IKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKVE 339 + ++ ++ + +++ + E+ + G PV + Sbjct: 336 VINNKPVRSPGEEGMQDVRLIQAIYEAARTGRPVNTD 372 >gb|AAD45293.1|AF156256_1 (AF156256) putative dehydrogenase [Vibrio anguillarum] Length = 318 Score = 84.3 bits (205), Expect = 2e-15 Identities = 73/268 (27%), Positives = 120/268 (44%), Gaps = 27/268 (10%) Query: 4 KLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFL 63 K+++ ++GCG I + H +++ L + ++VAV D + E + + S+D+ L Sbjct: 6 KIRIAVVGCGRI-SKNHFGSIEQLDSEYELVAVCDNNPEVLELHSNKYGVPGYHSIDDLL 64 Query: 64 -EQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFV 122 Q +++V + TP+ HA I+A KAG HVI EKP+A E+ M+K ++ ++LFV Sbjct: 65 ASQTLDIVTLCTPSGIHAPQTIKAAKAGVHVITEKPMATKWEDGLAMVKACDDAGVRLFV 124 Query: 123 GHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPF----PADY-----WYWDESKSGG 173 R + +K R + + KI + HL P +Y W GG Sbjct: 125 VKQNRRNSTLQLLK-----RAVTEKRFGKIHMVHLNVFWTRPQEYYDRAAWSGTWHMDGG 179 Query: 174 VIVDLGVHVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEV 233 ++ H D L W PIE A+ R + D V+ IK+ G G V Sbjct: 180 AFMNQATHYVDLLHWLV--GPIETI---HAMTSTHRDIEVEDTGVVNIKWRNGALGSMAV 234 Query: 234 SW-SYPMPPKYGVFYHHLDIIGKNGRIR 260 + +YP + I G+ G +R Sbjct: 235 TMCTYP-----NNLEGSITIFGEKGTVR 257 >sp|O32223|YVAA_BACSU HYPOTHETICAL OXIDOREDUCTASE IN FHUD-OPUBD INTERGENIC REGION >gi|7449498|pir||G70026 conserved hypothetical protein yvaA - Bacillus subtilis >gi|2635866|emb|CAB15358.1| (Z99121) similar to hypothetical proteins [Bacillus subtilis] Length = 358 Score = 83.1 bits (202), Expect = 4e-15 Identities = 85/364 (23%), Positives = 151/364 (41%), Gaps = 45/364 (12%) Query: 3 EKLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEF 62 + +KVGI+G G ++ H P L L + EE R +A+V L+E Sbjct: 12 DTIKVGILGYGLSGSVFHGPLLDVLDEYQISKIMTSRTEEVKRDFP---DAEVVHELEEI 68 Query: 63 LEQD-MNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLF 121 + +V + TP+ H E + ++AGKHV++EKP+ T EE E + + A+ + + L Sbjct: 69 TNDPAIELVIVTTPSGLHYEHTMACIQAGKHVVMEKPMTATAEEGETLKRAADEKGVLLS 128 Query: 122 VGHVRRFDKRWIQIKDIIKSRNILPMQIRKIEV-QHLPFPADYWYWDESKSGGVIVDLGV 180 V H RR+D ++ IK +I ++ + ++ ++ P W E + G + DLG Sbjct: 129 VYHNRRWDNDFLTIKKLISEGSLEDINTYQVSYNRYRPEVQARWREKEGTATGTLYDLGS 188 Query: 181 HVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWSYPMP 240 H+ D + + +F + KA+ + + V + + + + + Sbjct: 189 HIID--------QTLHLFGMPKAVTANVMAQRENAETVDYFHLTLDYGKLQAILYGGSIV 240 Query: 241 PKYGVFY--HHLD-------IIGKNGRIR--YTPMD--------------TPVVGVVKSS 275 P G Y H D I G+ +R P D T + G K + Sbjct: 241 PANGPRYQIHGKDSSFIKYGIDGQEDALRAGRKPEDDSWGADVPEFYGKLTTIRGSDKKT 300 Query: 276 FEMPRFSPMLSTFPQAFEAELRHFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEP 335 +P + T+ R E I+ VTA++ + ++I E A ES K+ Sbjct: 301 ETIPSVNGSYLTY-------YRKIAESIREGAALPVTAEEGINVIRIIEAAMESSKEKRT 353 Query: 336 VKVE 339 + +E Sbjct: 354 IMLE 357 >sp|P74041|Y816_SYNY3 HYPOTHETICAL 41.5 KD PROTEIN SLL0816 >gi|7469938|pir||S75555 hypothetical protein sll0816 - Synechocystis sp. (strain PCC 6803) >gi|1653200|dbj|BAA18116.1| (D90911) hypothetical protein [Synechocystis sp.] Length = 371 Score = 81.1 bits (197), Expect = 2e-14 Identities = 60/194 (30%), Positives = 98/194 (49%), Gaps = 12/194 (6%) Query: 5 LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELN-AKVFTSLDEFL 63 L V +IG G H PAL+ + + +A+ D A++ K + A + +L+E L Sbjct: 7 LTVAVIGTG-FGQAVHIPALQYHQQ-TQAIAIYHRDLAKAQEVAKSNDLAYSYNNLEELL 64 Query: 64 EQ-DMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFV 122 ++ V I +P + H E+A +A+ AGKHV++EKP+ L VEE ++ A +E+++ Sbjct: 65 ANPEVQAVTIASPPFLHYEMAKQAILAGKHVLLEKPMTLRVEETIELYHLARQREVQVIP 124 Query: 123 GHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHL------PFPADYWYWDESKSGGVIV 176 RF W + +++ + IL Q++ I+V L P A WY K GG + Sbjct: 125 DFEFRFVPAWQYVAELL-GQGILG-QLKLIKVDWLVGSRANPNRAWNWYAQREKGGGALG 182 Query: 177 DLGVHVTDFLRWFF 190 L H D+L W F Sbjct: 183 ALASHTFDYLHWLF 196 >pir||B75475 glucose-fructose oxidoreductase - Deinococcus radiodurans (strain R1) >gi|6458511|gb|AAF10376.1|AE001934_7 (AE001934) glucose-fructose oxidoreductase [Deinococcus radiodurans] Length = 398 Score = 80.8 bits (196), Expect = 2e-14 Identities = 78/346 (22%), Positives = 153/346 (43%), Gaps = 20/346 (5%) Query: 3 EKLKVG--IIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGK--ELNAKVFTS 58 E+ +VG I+G G + PA ++ + A + A++ +E+ + +L S Sbjct: 41 EQKRVGFAIVGIGKLSAEELIPAARTSQH-AYIAALVTSEEDKGEAFARAFDLTPDDVYS 99 Query: 59 LDEFLE----QDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAE 114 D+F + D+ V I+ P H E A K GKHV+ EKP+++ ++A+ M+ Sbjct: 100 YDDFEKLAGRDDVEAVYIVLPNSLHREYVERAAKMGKHVLCEKPLSVNEQDAQAMVDACR 159 Query: 115 NQELKLFVGHVRRFDKRWIQIKDIIKSRNILPMQ-IRKIEVQHLPFPADYWYWDESKSGG 173 + L + ++ +D ++ + ++ + I VQ P+ + + GG Sbjct: 160 AANVLLMTAYRCQYTPEHWAARDAVQGGKLGKVKLLDSIHVQSEDDPSVWRLKLDLAGGG 219 Query: 174 VIVDLGVHVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEV 233 + D+G++ + +R+ EP VFA G+ R + + V + F GG I V Sbjct: 220 PLPDVGLYSVNIIRFVLGQEPEWVFAALHQPEGDPRFGEVEESVSAMLGFPGGV--IANV 277 Query: 234 SWSYPMPPKYGVFYHHLDIIGKNGRIRYTPMDTPVVGV-VKSSFEMPRFSPMLSTFPQAF 292 SY + L ++G+ G + P P G+ ++ + + FSP + Q F Sbjct: 278 LTSYG-----ALKTTTLRVMGEEGSLLMDPA-FPYDGLGLEITTDDGTFSPSFPEYDQ-F 330 Query: 293 EAELRHFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKV 338 E HF +C++ P ++ + ++ + ES + G+ V++ Sbjct: 331 SREFDHFAQCVRGGQTPWTPGEEGVADHRVMDAIYESARTGKRVEL 376 >gb|AAD50452.1|AF170704_2 (AF170704) SpcB [Streptomyces spectabilis] Length = 374 Score = 80.0 bits (194), Expect = 4e-14 Identities = 42/142 (29%), Positives = 79/142 (55%), Gaps = 4/142 (2%) Query: 3 EKLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKEL---NAKVFTSL 59 E+++VG+IGCG + + H P L+SL ++ A+ D+ G+ + + FT Sbjct: 4 ERVRVGVIGCGTVAQIMHLPYLQSLSDQFEITALSDLSPGLLDALGERYGVPHGRRFTDY 63 Query: 60 DEFLEQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELK 119 L+ D++ V +L+ +HA + A +AGKHV+VEKP+ T+ EA+ + ++ Sbjct: 64 RALLDTDVDAVLVLSGG-SHAPQVLAAAEAGKHVLVEKPLCFTLREADAIEAAVARSGVR 122 Query: 120 LFVGHVRRFDKRWIQIKDIIKS 141 L V +++RFD ++ K ++ + Sbjct: 123 LMVAYMKRFDPGFLYGKQLVSA 144 >sp|P49305|YMO1_RHIME HYPOTHETICAL 36.4 KD PROTEIN IN MOCC-MOCA INTERGENIC REGION (ORF334) >gi|1073149|pir||S51570 hypothetical protein 334 - Rhizobium meliloti >gi|468760|emb|CAA55267.1| (X78503) ORF334 [Sinorhizobium meliloti] Length = 334 Score = 79.6 bits (193), Expect = 5e-14 Identities = 62/198 (31%), Positives = 95/198 (47%), Gaps = 3/198 (1%) Query: 5 LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELN-AKVFTSLDEFL 63 ++ GIIG I P++ S + +VVA+ D + AR A + + S DE L Sbjct: 4 VRFGIIGTAAIAVEKVIPSMLSAEGL-EVVAIASRDLDRARAAATRFGIGRSYGSYDEIL 62 Query: 64 -EQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFV 122 + ++ V I P + H AI A +AGKHV+ EKP+AL VEE ++I + ++ Sbjct: 63 ADPEIEAVYIPLPNHLHVHWAIRAAEAGKHVLCEKPLALDVEELSRLIDCRDRTGRRIQE 122 Query: 123 GHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPADYWYWDESKSGGVIVDLGVHV 182 + R +W +I DI+ S I ++ + + D S GG + DLGV+ Sbjct: 123 AVMIRAHPQWDEIFDIVASGEIGEVRAIQGVFTEVNLDPKSIVNDASIGGGALYDLGVYP 182 Query: 183 TDFLRWFFESEPIEVFAV 200 R F +EP VFAV Sbjct: 183 IAAARMVFAAEPERVFAV 200 >gb|AAF63338.1|AF244574_1 (AF244574) myo-inositol-2-dehydrogenase [Streptomyces spectabilis] Length = 374 Score = 79.2 bits (192), Expect = 6e-14 Identities = 42/142 (29%), Positives = 78/142 (54%), Gaps = 4/142 (2%) Query: 3 EKLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNA---KVFTSL 59 E+++VG+IGCG + + H P L+SL ++ A+ D+ G+ + FT Sbjct: 4 ERVRVGVIGCGTVAQIMHLPYLQSLPDQFEITALSDLSPGLLDALGERYGVPPGRRFTDY 63 Query: 60 DEFLEQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELK 119 L+ D + V +L+ +HA + A++AGKHV+VEKP+ T+ EA+ + ++ Sbjct: 64 RALLDTDADAVLVLSGG-SHAPQVLAAVEAGKHVLVEKPLCFTLREADAIEAAVARSGVR 122 Query: 120 LFVGHVRRFDKRWIQIKDIIKS 141 L V +++RFD ++ K ++ + Sbjct: 123 LMVAYMKRFDPGFLYGKQLVSA 144 >pir||T44834 hypothetical protein weeE [imported] - Acinetobacter lwoffii >gi|6009995|emb|CAB57202.1| (AJ243431) unknown [Acinetobacter lwoffii] Length = 712 Score = 78.8 bits (191), Expect = 8e-14 Identities = 74/236 (31%), Positives = 103/236 (43%), Gaps = 25/236 (10%) Query: 7 VGIIGCGNIFNLAHKPALKS----LRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEF 62 VG IG GN + PA K L TI + + K G A+ T LD Sbjct: 393 VGFIGAGNYASRVLIPAFKKASSQLHTIVTSGGINGVIH--GEKTGF---AEASTDLDGL 447 Query: 63 LE-QDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKM-----IKEAENQ 116 L +D+N V I T +HA L AGK+V VEKP+ALTVEE EK+ NQ Sbjct: 448 LNNKDINTVAIATRHNSHAYFVERVLSAGKNVFVEKPLALTVEEIEKIETVYNQNIQNNQ 507 Query: 117 ELKLFVGHVRRFDKRWIQIK---DIIKSRNILPMQIRKIEVQHLPFPADYWYWDESKSGG 173 ++ VG RRF + ++K D +K M + + PAD+W D + GG Sbjct: 508 YARVMVGFNRRFSPQVQKMKTLLDTVKEPKSFIMTMNAGAI-----PADHWTQDNAVGGG 562 Query: 174 VIVDLGVHVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTG 229 I+ H D +R+ S+ + V A + + V D + + FE G G Sbjct: 563 RIIGEACHFIDLMRFLAGSKIVSVQA--RRMGETDAVQVLEDKASITLGFEDGSFG 616 >pir||T38428 hypothetical oxidoreductase - fission yeast (Schizosaccharomyces pombe) >gi|2398818|emb|CAB16194.1| (Z99126) hypothetical oxidoreductase [Schizosaccharomyces pombe] Length = 369 Score = 78.0 bits (189), Expect = 1e-13 Identities = 58/186 (31%), Positives = 92/186 (49%), Gaps = 8/186 (4%) Query: 5 LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMD----IDEEAARKAGKELNAKVFTSLD 60 +K ++G G + H P LK+L +V A + E AR A N KV+T LD Sbjct: 4 IKTAVLGTGMSAFIFHYPFLKALPNHFEVYAAWERRATSTESKARAAFP--NVKVYTKLD 61 Query: 61 EFL-EQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELK 119 E L + ++ +V I P H E+ +AL AGKHV+ EKP T EA+++ A+++ L Sbjct: 62 ELLADSNIELVVISLPPNVHYEVVSQALNAGKHVLCEKPFTPTYGEAKELFDLAKSKNLM 121 Query: 120 LFVGHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLP-FPADYWYWDESKSGGVIVDL 178 L V RRFD ++ K+ I++ + + + + F W + G++ DL Sbjct: 122 LTVYQNRRFDGDFLTAKECIENGRLGEVVQFESHIDRFRLFRKGNWKDVPNPGCGLVYDL 181 Query: 179 GVHVTD 184 G H+ D Sbjct: 182 GSHLID 187 >sp|Q05184|PHT4_PSEPU PUTATIVE 4,5,-DIHYDROXYPHTHALATE DEHYDROGENASE (DHP DEHYDROGENASE) >gi|295711|dbj|BAA02512.1| (D13229) PHT4 [Pseudomonas putida] Length = 410 Score = 77.6 bits (188), Expect = 2e-13 Identities = 51/199 (25%), Positives = 98/199 (48%), Gaps = 5/199 (2%) Query: 4 KLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFL 63 +L++G++G G F L L R ++V D E+A R+ ++ +A + ++++ Sbjct: 11 RLRLGVVGLGRAFTLMLPTFLADRRV--QLVGACDPREQARRQFERDFDAPAYETIEDLA 68 Query: 64 -EQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFV 122 + +++ + I +P HAE A KHV+VEKP+AL+++E ++MI + +KL V Sbjct: 69 ADSNVDALYIASPHQFHAEHTRIAAANRKHVLVEKPMALSLDECDRMIADCAEAGVKLIV 128 Query: 123 GHVRRFDKRWIQIKDIIKSRNILPMQIRKI--EVQHLPFPADYWYWDESKSGGVIVDLGV 180 GH FD +++ +++I S +++ + +L P ++ GG + Sbjct: 129 GHCHSFDTPYLRTRELIGSGEFGAVKMIQALNYTDYLQRPRRPEELSTAEGGGAVFSQAA 188 Query: 181 HVTDFLRWFFESEPIEVFA 199 H D +R S V A Sbjct: 189 HQVDVVRLLAGSRATRVRA 207 >pir||G72391 conserved hypothetical protein - Thermotoga maritima (strain MSB8) >gi|4980813|gb|AAD35400.1|AE001713_4 (AE001713) conserved hypothetical protein [Thermotoga maritima] Length = 328 Score = 77.3 bits (187), Expect = 2e-13 Identities = 66/263 (25%), Positives = 118/263 (44%), Gaps = 18/263 (6%) Query: 4 KLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKEL-NAKVFTSLDEF 62 K+++GI+GCG H PALK+L + ++ AV A + K + N VF S +E Sbjct: 6 KIRLGIVGCGIAARELHLPALKNLSHLFEITAVTSRTRSHAEEFAKMVGNPAVFDSYEEL 65 Query: 63 LEQDM-NVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLF 121 LE + + V++ P + +AL+ G HVI EKPI+ VE +K+++ +E E ++ Sbjct: 66 LESGLVDAVDLTLPVELNLPFIEKALRKGVHVICEKPISTDVETGKKVVELSEKSEKTVY 125 Query: 122 VGHVRRFDKRWIQIKDIIKSRNI-----LPMQIRKIEVQHLPFPADYWYWDESKSGGVIV 176 + R + + K++++S I + QI ++ + W GG + Sbjct: 126 IAENFRHVPAFWKAKELVESGAIGDPVFMNWQIWVGMDENNKYVHTDWRKKPKHVGGFLS 185 Query: 177 DLGVHVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWS 236 D GVH +R E+ + + + + D + +FE G G +S+S Sbjct: 186 DGGVHHAAAMRLILG----EIEWISAVAKDLSPLLGGMDFLSSIFEFENGTVGNYTISYS 241 Query: 237 YPMPPKYGVFYHHLDIIGKNGRI 259 ++ +I G G+I Sbjct: 242 LKGNERF-------EITGTKGKI 257 >pir||A83004 conserved hypothetical protein PA5149 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9951449|gb|AAG08534.1|AE004927_12 (AE004927) conserved hypothetical protein [Pseudomonas aeruginosa] Length = 360 Score = 77.3 bits (187), Expect = 2e-13 Identities = 57/210 (27%), Positives = 102/210 (48%), Gaps = 18/210 (8%) Query: 5 LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFLE 64 ++ +IG G H P ++++ + V + R A+V DE +E Sbjct: 11 IRTALIGYGFAGKTFHAPLIRAVPALCLEHVV---SRDPGRVHADLPEARVSADPDEAIE 67 Query: 65 Q-DMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEK---MIKEAENQELKL 120 D+++V I +P THA LA AL+AGKHV+V+KP +T+ EA + + +E Q L + Sbjct: 68 AADIDLVVIASPNATHASLAERALRAGKHVVVDKPFTVTLAEARRLADLARERPGQVLSV 127 Query: 121 FVGHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHL-PFPADYWYWDESKSGGVIVDLG 179 F RRFD ++ ++ +++ +I P++ + ++ P D W + G+ DLG Sbjct: 128 FQN--RRFDSDFLAVEAALQAGSIGPVRYFESAIERFRPQVRDRWREHDLPGSGLWFDLG 185 Query: 180 VHVTDFLRWFFESEPIEVFAVGKAIRGEAR 209 H+ D + + +F V + + G R Sbjct: 186 PHLLD--------QALCLFGVPQRVHGHLR 207 >gb|AAF13758.1|AF117351_15 (AF117351) MviM [Zymomonas mobilis] Length = 358 Score = 76.9 bits (186), Expect = 3e-13 Identities = 58/187 (31%), Positives = 94/187 (50%), Gaps = 11/187 (5%) Query: 3 EKLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEF 62 E +KVG+IG G + H P + ++ + ++ A++ E R+ ++ V+ +D Sbjct: 6 EIIKVGLIGYGYVGKTFHAPFIDAVEGL-ELSAIVSSHPETVREDWPDM--AVYPDIDIM 62 Query: 63 LEQ-DMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLF 121 L ++++V I TP TH LA AL AG+HV+V+KP LT E+A + AE ++ L Sbjct: 63 LSNSNVDLVVIATPNDTHKPLAERALLAGRHVVVDKPFTLTTEDARYLAALAEKEKKLLS 122 Query: 122 VGHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHL----PFPADYWYWDESKSGGVIVD 177 V RR+D ++ +K I+ L I + E HL P W + GG+ D Sbjct: 123 VFQNRRWDSDFLGVKQAIEKD--LLGDIAQFE-SHLDRFRPVVRQRWREEAVAGGGLWYD 179 Query: 178 LGVHVTD 184 L H+ D Sbjct: 180 LAPHMVD 186 >pir||T39296 Oxidoreductase - fission yeast (Schizosaccharomyces pombe) >gi|2956751|emb|CAA17915.1| (AL022105) Oxidoreductase [Schizosaccharomyces pombe] Length = 368 Score = 76.5 bits (185), Expect = 4e-13 Identities = 55/189 (29%), Positives = 99/189 (52%), Gaps = 13/189 (6%) Query: 5 LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMD----IDEEAARKAGKELNAKVFTSLD 60 +K ++G G + H P L++L + ++ A ++ + + AR A N V+T+LD Sbjct: 4 IKTAVLGTGVSAFVFHFPFLEALPSKFEIYACLERRATVTQSKARSAYP--NILVYTNLD 61 Query: 61 EFL-EQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELK 119 E L + ++ +V + P H+E+ +AL AGKHV+ EKP T EEA+++ + AE++ L Sbjct: 62 ELLADVNIELVVVSLPPNVHSEIVKKALNAGKHVVCEKPFTPTYEEAKELYELAESKSLL 121 Query: 120 LFVGHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQ----HLPFPADYWYWDESKSGGVI 175 L + RR+D ++ K II+S + Q+ + E L + W + G++ Sbjct: 122 LAIYQNRRWDGDFLTAKKIIESGRL--GQVVEFESHFDRYRLGRKSGSWKDEPRPGNGMV 179 Query: 176 VDLGVHVTD 184 +G H+ D Sbjct: 180 YGIGSHLID 188 >gb|AAD45545.1|U70376_10 (U70376) SpcB [Streptomyces flavopersicus] Length = 392 Score = 76.5 bits (185), Expect = 4e-13 Identities = 37/130 (28%), Positives = 72/130 (54%), Gaps = 4/130 (3%) Query: 3 EKLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKV---FTSL 59 +++++G+IGCG + + H P L+SL ++ A+ D+ G+ F Sbjct: 21 QRIRIGVIGCGTVAQIMHLPYLRSLPAQFEIFALSDLSPGLLDLLGERYGVPATRRFLDY 80 Query: 60 DEFLEQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELK 119 LE +++ V +L+ +HA + A +AGKH++VEKP+ T+ EA+++ +++ Sbjct: 81 RGLLESEVDAVLVLSAG-SHAPQVLAAAEAGKHILVEKPLCFTLREADEIAAAVSRSQVR 139 Query: 120 LFVGHVRRFD 129 L V +++RFD Sbjct: 140 LMVAYMKRFD 149 >emb|CAB65577.1| (AL136058) putative oxidoreductase. [Streptomyces coelicolor A3(2)] Length = 360 Score = 75.3 bits (182), Expect = 1e-12 Identities = 52/187 (27%), Positives = 94/187 (49%), Gaps = 9/187 (4%) Query: 5 LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFLE 64 L+VG++G G ++ H P + + +A V E + + + + + DE + Sbjct: 11 LRVGLVGYGLAGSVFHAPLIAATEGLALDTVVTSNPERQQQARAEFPDVRTVATPDELFD 70 Query: 65 Q--DMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFV 122 + ++++V + +P TH LA AL+AG V+V+KP+A T EA + AE + L L V Sbjct: 71 RAAELDLVVVASPNKTHVPLATRALEAGLPVVVDKPVAGTAAEARALAALAEERGLLLSV 130 Query: 123 GHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQH---LPFPADYW--YWDESKSGGVIVD 177 RR+D ++ ++ ++ + ++ + E + P P W D S+ GG++ D Sbjct: 131 FQNRRWDNDFLTLRQLLAEDAL--GEVWRFESRFERWRPKPKGGWRESGDPSEIGGLLYD 188 Query: 178 LGVHVTD 184 LG HV D Sbjct: 189 LGSHVVD 195 >gb|AAG09709.1|AF218837_4 (AF218837) unknown [Pasteurella multocida] Length = 367 Score = 75.3 bits (182), Expect = 1e-12 Identities = 71/265 (26%), Positives = 114/265 (42%), Gaps = 25/265 (9%) Query: 5 LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFLE 64 +K G++G G + A + AKV V D E KEL TSL + + Sbjct: 2 MKYGVVGVG--YFGADLARFMNENENAKVTMVYD--PENGETIAKELQCIAATSLKQLVS 57 Query: 65 Q-DMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVG 123 +++ V + TP Y H E IEA K GKHV EKPIAL ++ ++M++ E + G Sbjct: 58 SPEVDCVIVATPNYLHKEPVIEAAKHGKHVFCEKPIALNYQDCDEMVRTCEENGVIFMAG 117 Query: 124 HVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHL-------PFPADYWYWDESKSGGVIV 176 HV F K++IK I K+ H + W +KSGG + Sbjct: 118 HVMNFFNGVHHAKELIKQG-----VIGKVLYCHSARNGWEDEQSSISWKKIRAKSGGHLY 172 Query: 177 DLGVHVTDFLRWFFESEPIEV-FAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSW 235 +H D +++ P V G + D + + ++FEGG+ + E Sbjct: 173 H-HIHELDCIQFIMGGMPKTVTMTAGNVAHQSEKFGDEDDMLFLNLEFEGGRFAVLEWGS 231 Query: 236 SYPMPPKYGVFYHHLDIIGKNGRIR 260 ++ ++G H++ I G+ G I+ Sbjct: 232 AF----RWG--EHYVLIQGEKGAIK 250 >emb|CAC11395.1| (AL445063) glucose-fructose oxidoreductase related protein [Thermoplasma acidophilum] Length = 322 Score = 74.5 bits (180), Expect = 2e-12 Identities = 71/266 (26%), Positives = 119/266 (44%), Gaps = 34/266 (12%) Query: 5 LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNA-KVFTSLDEFL 63 + + ++GC K L+ + V++++ D A++ + KV+ + ++ L Sbjct: 1 MDIVLVGCKGF----GKEHLRIYSKLGYDVSIVERDSNEAKRCSELFRVYKVYDNYEDAL 56 Query: 64 EQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVG 123 N+V+++ P H E+ ALK+ KH++VEKPI ++ +I++AE +LKL V Sbjct: 57 RSGSNIVDLVVPDGLHYEMGSLALKSKKHLLVEKPITPDIDSGISLIQQAEESKLKLMVA 116 Query: 124 HVRRFDKRWIQIKDIIKSRNILPMQIRK---IEVQHLPF-PADYWYWDESKSG-GVIVDL 178 FD + + I R I +I K + V+H F W ++S G G+++D Sbjct: 117 EQFYFDP---SVNEAI--RRINNGEIGKPHTVIVRHQSFRELKGWRNEKSMMGRGILIDE 171 Query: 179 GVHVTDFLRWFFESEPIEVFAVGKAIRGEARVNKT-----HDHVVMFIKFEGGKTGIGEV 233 G H D L F G+ + V++T D FE G G+ Sbjct: 172 GTHYIDTLLNF----------GGRYRSLRSFVHRTWDFLGEDTAEAVFNFENGMHGLFFY 221 Query: 234 SWSYPMPPKYGVFYHHLDIIGKNGRI 259 SW+YP P F +IIG G I Sbjct: 222 SWNYPEYPLLPEF----EIIGDAGSI 243 >sp|Q07982|GFO_ZYMMO GLUCOSE--FRUCTOSE OXIDOREDUCTASE PRECURSOR (GFOR) >gi|95542|pir||A42289 glucose-fructose oxidoreductase (EC 1.1.-.-) precursor - Zymomonas mobilis >gi|155588|gb|AAA27690.1| (M97379) glucose-fructose oxidoreductase [Zymomonas mobilis] Length = 439 Score = 73.7 bits (178), Expect = 3e-12 Identities = 59/276 (21%), Positives = 119/276 (42%), Gaps = 6/276 (2%) Query: 67 MNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVGHVR 126 ++ V I+ P HAE AI + KAGKHV+ EKP+A +V + ++MI A+ KL +G+ Sbjct: 150 IDAVYIILPNSLHAEFAIRSFKAGKHVMCEKPMATSVADCQRMIDAAKAANKKLMIGYRC 209 Query: 127 RFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPADY---WYWDESKSGGVIVDLGVHVT 183 +D +I+ + + + + + D + GG ++D+G++ Sbjct: 210 HYDPMNRAAVKLIRENQLGKLGMVTTDNSDVMDQNDLHSSGVCVVNSGGGSLMDIGIYGL 269 Query: 184 DFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWSYPMPPKY 243 + R+ EPIEV A + + R + D ++ ++F G G S+S ++ Sbjct: 270 NGTRYLLGEEPIEVRAYTYSDPNDERFVEVEDRIIWQMRFRSGALSHGASSYSTTTTSRF 329 Query: 244 GVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPRFSPMLSTFPQAFEAELRHFFECI 303 V ++ Y + + + MP+F + F A+L H E + Sbjct: 330 SVQGDKAVLLMDPATGYYQNLISVQTPGHANQSMMPQF---IMPANNQFSAQLDHLAEAV 386 Query: 304 KSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKVE 339 ++ ++ + +++ + E+ + G V + Sbjct: 387 INNKPVRSPGEEGMQDVRLIQAIYEAARTGRAVNTD 422 >dbj|BAB07562.1| (AP001520) oxidoreductase [Bacillus halodurans] Length = 334 Score = 73.7 bits (178), Expect = 3e-12 Identities = 70/263 (26%), Positives = 116/263 (43%), Gaps = 16/263 (6%) Query: 1 MPEKLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDI-DEEAARKAGKELNA-KVFTS 58 M ++ GI+G I PA+K A+VVAV D E A E + K + Sbjct: 1 MGNNVRWGILGTAGIAKKQLIPAIKRASN-AEVVAVSSRNDMEKANCYADECDIPKRYAR 59 Query: 59 LDEFL-EQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQE 117 ++ L + D++ V I P + H A +A + GKHV+ EKP ALT EA++M+ Sbjct: 60 YEDLLNDPDIDAVYIPLPNHLHLTWAKKAAEHGKHVLCEKPAALTAAEAKEMVDACAAHG 119 Query: 118 LKLFVGHVRRFDKRWIQIKDIIKSRNILPMQ-IRKIEVQHLPFPADYWYWDESKSGGVIV 176 + + +F + ++K +I S I ++ IR LP A+ + GG + Sbjct: 120 VVFMEAFMYQFHPQHGEVKRLIDSGKIGEVRLIRSNFSFQLPLEANNIRLNREMGGGSLY 179 Query: 177 DLGVHVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWS 236 D+G + R+ EP+ + G + E V+ + V ++ EGG T + S+ Sbjct: 180 DVGCYCIHLTRYLTGKEPVHAYGTG-YLHPELGVDTSFTGV---LQMEGGVTSVFTSSFE 235 Query: 237 YPMPPKYGVFYHHLDIIGKNGRI 259 P Y +++G G I Sbjct: 236 QPADDSY-------EVVGTEGTI 251 >gb|AAD03557.1| (AF095748) phthalate dihydrodiol dehydrogenase [Burkholderia cepacia] Length = 391 Score = 73.4 bits (177), Expect = 4e-12 Identities = 48/192 (25%), Positives = 92/192 (47%), Gaps = 15/192 (7%) Query: 4 KLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFL 63 +L++G+ G G F+L L+ R ++VA D +EA R+ + A + + E Sbjct: 5 RLRIGVAGLGRAFSLMLPTFLRDSRV--QLVAACDPRDEARRQFAADFAAPTYADVAELA 62 Query: 64 -EQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFV 122 + ++ ++ + +P HA+ A GKHV+VEKP+AL + ++MI + L V Sbjct: 63 NDPNVEIIYVASPHQFHAQHTEIAAAKGKHVLVEKPMALAAADCDRMIAACRAANVHLIV 122 Query: 123 GHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPADYWYWDE-------SKSGGVI 175 GH FD +++ +++I + +++ +Q + + DY Y ++ GG + Sbjct: 123 GHCHSFDTPYLRTRELISLGDFGAVKM----IQAVNY-TDYLYRPRRPEELATAEGGGAV 177 Query: 176 VDLGVHVTDFLR 187 H D +R Sbjct: 178 FSQAAHQVDIVR 189 >dbj|BAA97119.1| (AB035122) 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase [Sphingomonas paucimobilis] Length = 315 Score = 73.0 bits (176), Expect = 5e-12 Identities = 69/255 (27%), Positives = 113/255 (44%), Gaps = 24/255 (9%) Query: 5 LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFLE 64 +++ + G G F H LK++ + V + E+AA A K T L E L Sbjct: 1 MRIALAGAG-AFGEKHLDGLKNIDGVEIVSIISRKAEQAAEVAAKYGAKHSGTDLSEALA 59 Query: 65 QD-MNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVG 123 +D ++ V + TPT HAE AI + AGKHV VE P+A + +AE ++K+++ L VG Sbjct: 60 RDDVDAVILCTPTQMHAEQAIACMNAGKHVQVEIPLADSWADAEAVMKKSQETGLVCMVG 119 Query: 124 HVRRFD--KRWIQIKDIIKSRNILPMQIRKIEVQHLPFPADYWYWDESKSGGVIVDLGVH 181 H RRF+ ++I K + I M ++ + A E +S Sbjct: 120 HTRRFNPSHQYIHNKIVAGELAIQQMDVQTYFFRRKNMNAK----GEPRSW--------- 166 Query: 182 VTDFLRWFFESEPIEVFA--VGKAIRGEARVNKTHDH----VVMFIKFEGGKTGIGEVSW 235 TD L W + +++FA GK ++ A H + M I+ + I +S Sbjct: 167 -TDHLLWHHAAHTVDLFAYQAGKIVQANAVQGPIHPELGIAMDMSIQLKSETGAICTLSL 225 Query: 236 SYPMPPKYGVFYHHL 250 S+ G F+ ++ Sbjct: 226 SFNNDGPLGTFFRYI 240 >pir||A81396 hypothetical protein Cj0504c [imported] - Campylobacter jejuni (strain NCTC 11168) >gi|6967973|emb|CAB75141.1| (AL139075) hypothetical protein Cj0504c [Campylobacter jejuni] Length = 288 Score = 73.0 bits (176), Expect = 5e-12 Identities = 53/209 (25%), Positives = 105/209 (49%), Gaps = 15/209 (7%) Query: 5 LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFLE 64 +K+GIIG G + H L S + K+ A+ D+ + ++ + LD+FL Sbjct: 1 MKIGIIGLGKM-GQNHLNEL-SKNSHFKLNALFDLCKNPNLNIFDDI---FYDDLDKFLN 55 Query: 65 QDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVGH 124 Q+ +++ I TPT +H +A + K K V++EKP+AL ++E +++ A+ +K+ VG Sbjct: 56 QNNDIIIIATPTNSHLTIAKKVFKQCKCVLIEKPLALNLKEIDEISNLAKEYSIKVGVGF 115 Query: 125 VRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPADYWYWDESKSGGVIVDLGVHVTD 184 RF+ + +K +++ I+ + I++ P+P G++ DL VH D Sbjct: 116 CERFNPAVLALKKELENEEIISINIQRFS----PYP------QRISDVGILQDLAVHDLD 165 Query: 185 FLRWFFESEPIEVFAVGKAIRGEARVNKT 213 L + + E + + K + + R +++ Sbjct: 166 LLCFLSKQEITKTNLLKKYTQDQTRESES 194 >pir||T36464 probable oxidoreductase - Streptomyces coelicolor >gi|5824085|emb|CAB54161.1| (AL110470) putative oxidoreductase [Streptomyces coelicolor A3(2)] Length = 417 Score = 72.6 bits (175), Expect = 6e-12 Identities = 56/221 (25%), Positives = 102/221 (45%), Gaps = 13/221 (5%) Query: 5 LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTS--LDEF 62 L+VG++G G ++A AL + A++V+ D D A + A V + Sbjct: 12 LRVGVVGVGQRADMA---ALVNRSGAARIVSCADPDPRGREDARRLFGADVVVHDRYERM 68 Query: 63 LEQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFV 122 L+ +++ V +LTP + H E A+ L AG V VEKP+ +TV + + ++ A +L+V Sbjct: 69 LDDELDAVFVLTPDHLHTEPALCFLAAGVAVFVEKPLTITVADCDALLMAAFRSRTRLYV 128 Query: 123 GHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHL-----PFPADYWYWDESKSGGVIVD 177 GH R +++++I + ++R + +H F W+ + + G+++ Sbjct: 129 GHNLRHLPVLRRMRELIDDGAV--GRVRAVWCRHFVGHGGDFYFKDWHAQRANTTGLLLQ 186 Query: 178 LGVHVTDFLRWFFESEPIEVFAVGK-AIRGEARVNKTHDHV 217 G H D + W V A G A+ G+ T + V Sbjct: 187 KGAHDLDVVHWLAGGFSRNVVAQGALAVYGDNPRRATQETV 227 >pir||B64919 conserved hypothetical protein b1624 - Escherichia coli >gi|1742678|dbj|BAA15375.1| (D90805) Virulence factor MviM. [Escherichia coli] >gi|1742686|dbj|BAA15382.1| (D90806) Virulence factor MviM. [Escherichia coli] >gi|1742694|dbj|BAA15389.1| (D90807) Virulence factor MviM. [Escherichia coli] >gi|1742718|dbj|BAA15412.1| (D90808) Virulence factor MviM. [Escherichia coli] >gi|1787911|gb|AAC74696.1| (AE000258) orf, hypothetical protein [Escherichia coli K12] Length = 359 Score = 71.8 bits (173), Expect = 1e-11 Identities = 51/185 (27%), Positives = 87/185 (46%), Gaps = 3/185 (1%) Query: 1 MPEKLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLD 60 M + ++VG+IG G H P + T + +AV+ +E KA V Sbjct: 14 MSDNIRVGLIGYGYASKTFHAPLIAG--TPGQELAVISSSDETKVKADWPTVTVVSEPKH 71 Query: 61 EFLEQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKL 120 F + +++++ I TP TH LA AL+AGKHV+V+KP +T+ +A ++ A++ L Sbjct: 72 LFNDPNIDLIVIPTPNDTHFPLAKAALEAGKHVVVDKPFTVTLSQARELDALAKSLGRVL 131 Query: 121 FVGHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHL-PFPADYWYWDESKSGGVIVDLG 179 V H RR+D ++ +K ++ + + + P D W G+ DL Sbjct: 132 SVFHNRRWDSDFLTLKGLLAEGVLGEVAYFESHFDRFRPQVRDRWREQGGPGSGIWYDLA 191 Query: 180 VHVTD 184 H+ D Sbjct: 192 PHLLD 196 >sp|P77376|YDGJ_ECOLI HYPOTHETICAL OXIDOREDUCTASE IN ADD-NTH INTERGENIC REGION Length = 346 Score = 71.8 bits (173), Expect = 1e-11 Identities = 51/185 (27%), Positives = 87/185 (46%), Gaps = 3/185 (1%) Query: 1 MPEKLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLD 60 M + ++VG+IG G H P + T + +AV+ +E KA V Sbjct: 1 MSDNIRVGLIGYGYASKTFHAPLIAG--TPGQELAVISSSDETKVKADWPTVTVVSEPKH 58 Query: 61 EFLEQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKL 120 F + +++++ I TP TH LA AL+AGKHV+V+KP +T+ +A ++ A++ L Sbjct: 59 LFNDPNIDLIVIPTPNDTHFPLAKAALEAGKHVVVDKPFTVTLSQARELDALAKSLGRVL 118 Query: 121 FVGHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHL-PFPADYWYWDESKSGGVIVDLG 179 V H RR+D ++ +K ++ + + + P D W G+ DL Sbjct: 119 SVFHNRRWDSDFLTLKGLLAEGVLGEVAYFESHFDRFRPQVRDRWREQGGPGSGIWYDLA 178 Query: 180 VHVTD 184 H+ D Sbjct: 179 PHLLD 183 >gb|AAF51262.1| (AE003583) CG3609 gene product [Drosophila melanogaster] Length = 335 Score = 70.2 bits (169), Expect = 3e-11 Identities = 62/234 (26%), Positives = 106/234 (44%), Gaps = 16/234 (6%) Query: 1 MPEKLKVGIIGCGNI---FNLAHKPALKSLRTIAKVVA-VMDIDEEAARKAGKELNAKVF 56 M + ++ GI G I F +A S + V A +D +E A K G K Sbjct: 1 MSKLIRWGIASAGKISEDFVIALSTLPSSDHKVQAVAARALDRAQEFATKHGIP---KAL 57 Query: 57 TSLDEFLEQ-DMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAEN 115 S +E + D++VV I T H E+A+ L GKHV+ EKP+A+ ++ E ++ A+ Sbjct: 58 GSYEELAKSTDVDVVYIGTLNPQHYEVALLMLNNGKHVLCEKPLAMNKKQVEGILAAAKA 117 Query: 116 QELKLFVGHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQH-LPFPADYWYWDESKSGGV 174 + RF + ++K++I S + Q++ +EV P P GGV Sbjct: 118 NKRFFMEAVWSRFFPSYQRVKELISSGQL--GQVKDVEVNFGFPMPHVDRLQKRELGGGV 175 Query: 175 IVDLGVHVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKT 228 + DLG++ +W F+ +P ++ + +G D V + + GG+T Sbjct: 176 VYDLGIYTIQVSQWAFQEKPEKIES-----KGTLNAEGIDDDVSATLTYSGGRT 224 >sp|Q44258|CBAC_ALCSB 1-CARBOXY-3-CHLORO-3,4-DIHYDROXYCYCLO HEXA-1,5-DIENE DEHYDROGENASE >gi|2073552|gb|AAC45718.1| (U18133) 1-carboxy-3-chloro-3,4-dihydroxycyclohexa-1,5-diene dehydrogenase [Comamonas testosteroni] Length = 397 Score = 69.9 bits (168), Expect = 4e-11 Identities = 59/202 (29%), Positives = 91/202 (44%), Gaps = 16/202 (7%) Query: 5 LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFL- 63 +++G++G G F L L R ++VA D D + R+ + A E L Sbjct: 1 MRIGVVGLGKAFMLMLPTFLMDRRV--QLVAASDTDPLSLRQFKADFPAAAVHGDIESLC 58 Query: 64 -EQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFV 122 D+ VV I TP HA A AL AGKHV+VEKP+A+T+E+ +M A+ L V Sbjct: 59 KNPDVEVVYIGTPHQFHAVHAEIALNAGKHVLVEKPMAVTLEDCCRMNACAQRAGKYLIV 118 Query: 123 GHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPADYWY-------WDESKSGGVI 175 GH FD + K++I S + ++ H D+ Y + GGV+ Sbjct: 119 GHSHSFDHPISRAKELIDSG-----RYGRVRFIHSMNYTDFLYRPRRAEELNTDLGGGVV 173 Query: 176 VDLGVHVTDFLRWFFESEPIEV 197 + H D +R + ++V Sbjct: 174 FNQASHQLDVIRLLAQGRVVDV 195 >sp|P09400|STRI_STRGR STREPTOMYCIN BIOSYNTHESIS PROTEIN STRI >gi|80803|pir||S17779 strI protein - Streptomyces griseus >gi|49268|emb|CAA68521.1| (Y00459) NAD:myo-inositol oxidoreductase [Streptomyces griseus] Length = 348 Score = 69.1 bits (166), Expect = 7e-11 Identities = 77/349 (22%), Positives = 142/349 (40%), Gaps = 31/349 (8%) Query: 5 LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNA--KVFTSLDEF 62 ++VGI+G G + L H L L +V V D+D + A + +EL A K +++ Sbjct: 1 MRVGIVGAGRMGRL-HARTLLELPDPPDLV-VHDVDPDGAHRLAQELAAGTKAQVTVERE 58 Query: 63 LEQDM---NVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELK 119 L + + + + TP + A +AG V EKP+ EA ++++ + + Sbjct: 59 LADTVTKADAIVVATPATQRRAPLLAAARAGLPVFCEKPLTADETEAAELVEALAH--TR 116 Query: 120 LFVGHVRRFDKRWIQIKDIIKSRNI-LPMQIRKIEVQHLPFPADYWYWDESKSGGVIVDL 178 L VG RR D + +++++I + + + +R H P PAD + E +G + D Sbjct: 117 LHVGFQRRCDPEYQRLRELIAAGELGRVLLVRCTAFDHRP-PADAY---EETAGDIFTDC 172 Query: 179 GVHVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWSYP 238 +H D + W + V A G + +D + G + S P Sbjct: 173 LIHDIDAVHWLTGQPTVAVQADGARL----LAGSGYDVATAVLTLADGARAVLSASRLDP 228 Query: 239 MPPKYGVFYHHLDIIGKNGRIRY-----TP---MDTPVVGVVKSSFEMPRFSPMLSTFPQ 290 +G + H ++++G G + TP + G P + F Sbjct: 229 ----HG-YDHRVEVLGTKGSLSVGLDARTPLRLLGQDGTGCPPGPGAQPAYQDFTDRFEA 283 Query: 291 AFEAELRHFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKVE 339 A+ E+ F + T Q+AL A ++A A + + G V+++ Sbjct: 284 AYRREVLAFVRTVTEGAPSPCTGQEALRAQRVAAAAGRAARTGTRVELD 332 >dbj|BAB04427.1| (AP001509) unknown conserved protein [Bacillus halodurans] Length = 369 Score = 69.1 bits (166), Expect = 7e-11 Identities = 42/120 (35%), Positives = 70/120 (58%), Gaps = 5/120 (4%) Query: 5 LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFLE 64 +K G+IGCGNI ++ + + +VA D+ E AR ++ ++ E LE Sbjct: 4 IKAGLIGCGNISSIYFENVHRFKHLT--IVACADLHLERARAQAEKYRIPKACTVAELLE 61 Query: 65 Q-DMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVG 123 ++ +V LT HA++ I+AL+AGKHV EKP+ +T+EE +K++++A +E L VG Sbjct: 62 DPEIELVINLTIPQVHAKVCIQALEAGKHVYTEKPLTITLEEGQKLLEKA--KETGLLVG 119 >pir||T42744 hypothetical protein - fission yeast (Schizosaccharomyces pombe) (fragment) >gi|1749580|dbj|BAA13848.1| (D89186) similar to Escherichia coli hypothetical 38.8KD protein in GNTR-GGT intergenic region, SWISS-PROT Accession Number P46853 [Schizosaccharomyces pombe] Length = 352 Score = 68.7 bits (165), Expect = 9e-11 Identities = 49/169 (28%), Positives = 82/169 (47%), Gaps = 4/169 (2%) Query: 20 HKPALKSLRTIAKVVAVMDIDEEAARKAGKE--LNAKVFTSLDEFL-EQDMNVVEILTPT 76 H P LK+L +V A + + + N KV+T LDE L + ++ +V I P Sbjct: 2 HYPFLKALPNHFEVYAAWERRATSTESKARADFPNVKVYTKLDELLADSNIELVVISLPP 61 Query: 77 YTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVGHVRRFDKRWIQIK 136 H E+ +AL GKHV+ EKP T EA+++ A+++ L L + RRFD ++ K Sbjct: 62 NVHYEVVSQALNVGKHVLCEKPFTPTYGEAKELFDLAKSKNLMLTLYQNRRFDGDFLTAK 121 Query: 137 DIIKSRNILPMQIRKIEVQHLP-FPADYWYWDESKSGGVIVDLGVHVTD 184 + I++ + + + + F W + G++ DLG H+ D Sbjct: 122 ECIENGRLGEVVQFESHIDRFRLFRKGNWKDVPNPGCGLVYDLGSHLID 170 >gb|AAF97051.1| (AF248034) WlbA [Bordetella avium] Length = 125 Score = 68.7 bits (165), Expect = 9e-11 Identities = 40/118 (33%), Positives = 65/118 (54%), Gaps = 2/118 (1%) Query: 4 KLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFL 63 K++ ++GCG I + H A+ A++V V D D A R A K AK ++SL E L Sbjct: 8 KIRFALVGCGRI-SKNHIAAIAQHHERAELVEVCDTDPAALRAAAKATGAKPYSSLSEML 66 Query: 64 EQDM-NVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKL 120 + V + TP+ H AIE ++G+HV+ EKP+A E+ ++M+K ++ + L Sbjct: 67 AASTADAVILATPSGLHPWQAIEVAQSGRHVVSEKPMATRWEDGKRMVKACDDAGVHL 124 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.321 0.138 0.406 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 126048172 Number of Sequences: 2977 Number of extensions: 5310718 Number of successful extensions: 12960 Number of sequences better than 1.0e-10: 67 Number of HSP's better than 0.0 without gapping: 5 Number of HSP's successfully gapped in prelim test: 62 Number of HSP's that attempted gapping in prelim test: 12855 Number of HSP's gapped (non-prelim): 76 length of query: 341 length of database: 189,106,746 effective HSP length: 55 effective length of query: 286 effective length of database: 156,189,961 effective search space: 44670328846 effective search space used: 44670328846 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.8 bits) S2: 165 (68.7 bits)