BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB1138 (PAB1138) DE:NADH-dependent DYHYDROGENASE RELATED
PROTEIN
         (341 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||A75025 NADH-dependent dyhydrogenase related protein PAB1138...   692  0.0
pir||D71201 hypothetical protein PH1881 - Pyrococcus horikoshii ...   651  0.0
pir||H69216 3-chlorobenzoate-3,4-dioxygenase dyhydrogenase relat...   132  4e-30
pir||E75096 NADH-dependent dehydrogenase homolog. PAB0775 - Pyro...   132  7e-30
pir||D72381 dehydrogenase - Thermotoga maritima (strain MSB8) >g...   127  1e-28
dbj|BAB04967.1| (AP001511) NADH-dependent dyhydrogenase [Bacillu...   126  4e-28
gb|AAC23913.1| (AF039207) NADH-dependent dehydrogenase homolog [...   122  5e-27
pir||B72359 lipopolysaccharide biosynthesis protein BplA - Therm...   120  2e-26
pir||B75025 NADH-dependent dyhydrogenase related protein PAB1139...   116  5e-25
sp|O05389|YRBE_BACSU HYPOTHETICAL 37.8 KDA PROTEIN IN CSBX-NADA ...   113  2e-24
sp|P40332|YISS_BACSU HYPOTHETICAL 37.5 KD PROTEIN IN DEGA-NPRB I...   113  2e-24
pir||E71201 probable glucose-fructose oxidoreductase - Pyrococcu...   112  5e-24
gb|AAK43115.1| Dehydrogenase, putative [Sulfolobus solfataricus]      107  2e-22
gb|AAK43149.1| Dehydrogenase, putative [Sulfolobus solfataricus]      106  5e-22
gb|AAC01706.1| (AF040570) unknown [Amycolatopsis mediterranei]        104  2e-21
gb|AAK43117.1| Dehydrogenase, putative [Sulfolobus solfataricus]      104  2e-21
emb|CAB88961.1| (AL353864) putative oxidoreductase. [Streptomyce...   103  3e-21
gb|AAC31183.1| (AF076240) putative NADH-inositol dehydrogenase M...    98  2e-19
sp|O68965|MI2D_RHIME MYO-INOSITOL 2-DEHYDROGENASE >gi|3088561|gb...    95  1e-18
emb|CAB60174.1| (AL132824) putative dehydrogenase [Streptomyces ...    94  3e-18
dbj|BAB05884.1| (AP001514) unknown conserved protein [Bacillus h...    94  3e-18
pir||S76068 hypothetical protein - Synechocystis sp. (strain PCC...    93  4e-18
pir||A69834 conserved hypothetical protein yhjJ - Bacillus subti...    93  4e-18
dbj|BAB06035.1| (AP001515) myo-inositol 2-dehydrogenase [Bacillu...    90  3e-17
sp|P26935|MI2D_BACSU MYO-INOSITOL 2-DEHYDROGENASE >gi|80338|pir|...    90  4e-17
gb|AAK43113.1| Dehydrogenase, putative [Sulfolobus solfataricus]       89  8e-17
emb|CAC11912.1| (AL445065) hypothetical protein [Thermoplasma ac...    88  1e-16
pir||A82502 oxidoreductase, Gfo/Idh/MocA family VCA0099 [importe...    88  2e-16
sp|P49307|MOCA_RHIME RHIZOPINE CATABOLISM PROTEIN MOCA >gi|21208...    87  4e-16
dbj|BAB05939.1| (AP001514) dehydrogenase [Bacillus halodurans]         86  5e-16
emb|CAC12307.1| (AL445066) glucose-fructose oxidoreductase relat...    86  5e-16
dbj|BAB05940.1| (AP001514) unknown conserved protein [Bacillus h...    86  7e-16
pir||S70672 dehydrogenase homolog - Bordetella pertussis >gi|992...    85  9e-16
emb|CAB02496.1| (Z80356) glucose-fructose oxidoreductase [Zymomo...    85  1e-15
pdb|1OFG|A Chain A, Glucose-Fructose Oxidoreductase >gi|2098324|...    85  1e-15
gb|AAD45293.1|AF156256_1 (AF156256) putative dehydrogenase [Vibr...    84  2e-15
sp|O32223|YVAA_BACSU HYPOTHETICAL OXIDOREDUCTASE IN FHUD-OPUBD I...    83  4e-15
sp|P74041|Y816_SYNY3 HYPOTHETICAL 41.5 KD PROTEIN SLL0816 >gi|74...    81  2e-14
pir||B75475 glucose-fructose oxidoreductase - Deinococcus radiod...    81  2e-14
gb|AAD50452.1|AF170704_2 (AF170704) SpcB [Streptomyces spectabilis]    80  4e-14
sp|P49305|YMO1_RHIME HYPOTHETICAL 36.4 KD PROTEIN IN MOCC-MOCA I...    80  5e-14
gb|AAF63338.1|AF244574_1 (AF244574) myo-inositol-2-dehydrogenase...    79  6e-14
pir||T44834 hypothetical protein weeE [imported] - Acinetobacter...    79  8e-14
pir||T38428 hypothetical oxidoreductase - fission yeast  (Schizo...    78  1e-13
sp|Q05184|PHT4_PSEPU PUTATIVE 4,5,-DIHYDROXYPHTHALATE DEHYDROGEN...    78  2e-13
pir||G72391 conserved hypothetical protein - Thermotoga maritima...    77  2e-13
pir||A83004 conserved hypothetical protein PA5149 [imported] - P...    77  2e-13
gb|AAF13758.1|AF117351_15 (AF117351) MviM [Zymomonas mobilis]          77  3e-13
pir||T39296 Oxidoreductase - fission yeast (Schizosaccharomyces ...    76  4e-13
gb|AAD45545.1|U70376_10 (U70376) SpcB [Streptomyces flavopersicus]     76  4e-13
emb|CAB65577.1| (AL136058) putative oxidoreductase. [Streptomyce...    75  1e-12
gb|AAG09709.1|AF218837_4 (AF218837) unknown [Pasteurella multocida]    75  1e-12
emb|CAC11395.1| (AL445063) glucose-fructose oxidoreductase relat...    75  2e-12
sp|Q07982|GFO_ZYMMO GLUCOSE--FRUCTOSE OXIDOREDUCTASE PRECURSOR (...    74  3e-12
dbj|BAB07562.1| (AP001520) oxidoreductase [Bacillus halodurans]        74  3e-12
gb|AAD03557.1| (AF095748) phthalate dihydrodiol dehydrogenase [B...    73  4e-12
dbj|BAA97119.1| (AB035122) 4-carboxy-2-hydroxymuconate-6-semiald...    73  5e-12
pir||A81396 hypothetical protein Cj0504c [imported] - Campylobac...    73  5e-12
pir||T36464 probable oxidoreductase - Streptomyces coelicolor >g...    73  6e-12
pir||B64919 conserved hypothetical protein b1624 - Escherichia c...    72  1e-11
sp|P77376|YDGJ_ECOLI HYPOTHETICAL OXIDOREDUCTASE IN ADD-NTH INTE...    72  1e-11
gb|AAF51262.1| (AE003583) CG3609 gene product [Drosophila melano...    70  3e-11
sp|Q44258|CBAC_ALCSB 1-CARBOXY-3-CHLORO-3,4-DIHYDROXYCYCLO HEXA-...    70  4e-11
sp|P09400|STRI_STRGR STREPTOMYCIN BIOSYNTHESIS PROTEIN STRI >gi|...    69  7e-11
dbj|BAB04427.1| (AP001509) unknown conserved protein [Bacillus h...    69  7e-11
pir||T42744 hypothetical protein - fission yeast (Schizosaccharo...    69  9e-11
gb|AAF97051.1| (AF248034) WlbA [Bordetella avium]                      69  9e-11

>pir||A75025 NADH-dependent dyhydrogenase related protein PAB1138 - Pyrococcus
           abyssi (strain Orsay) >gi|5459153|emb|CAB50639.1|
           (AJ248288) NADH-dependent DYHYDROGENASE RELATED PROTEIN
           [Pyrococcus abyssi]
           Length = 341
           
 Score =  692 bits (1767), Expect = 0.0
 Identities = 341/341 (100%), Positives = 341/341 (100%)

Query: 1   MPEKLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLD 60
           MPEKLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLD
Sbjct: 1   MPEKLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLD 60

Query: 61  EFLEQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKL 120
           EFLEQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKL
Sbjct: 61  EFLEQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKL 120

Query: 121 FVGHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPADYWYWDESKSGGVIVDLGV 180
           FVGHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPADYWYWDESKSGGVIVDLGV
Sbjct: 121 FVGHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPADYWYWDESKSGGVIVDLGV 180

Query: 181 HVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWSYPMP 240
           HVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWSYPMP
Sbjct: 181 HVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWSYPMP 240

Query: 241 PKYGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPRFSPMLSTFPQAFEAELRHFF 300
           PKYGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPRFSPMLSTFPQAFEAELRHFF
Sbjct: 241 PKYGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPRFSPMLSTFPQAFEAELRHFF 300

Query: 301 ECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKVEVN 341
           ECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKVEVN
Sbjct: 301 ECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKVEVN 341


>pir||D71201 hypothetical protein PH1881 - Pyrococcus horikoshii
           >gi|3258320|dbj|BAA31003.1| (AP000007) 371aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 371
           
 Score =  651 bits (1660), Expect = 0.0
 Identities = 313/341 (91%), Positives = 334/341 (97%)

Query: 1   MPEKLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLD 60
           M E+LKVG+IGCGNIFNLAHKPAL+SLRTIAKVVAVMDI+EEAA+KAGKELNAKVFTSLD
Sbjct: 31  MSERLKVGVIGCGNIFNLAHKPALRSLRTIAKVVAVMDINEEAAKKAGKELNAKVFTSLD 90

Query: 61  EFLEQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKL 120
           EFLEQDM+VVE+LTPTYTHAE+AI+ALKAGKHVIVEKPIALT EEAEKMIKEAE Q LKL
Sbjct: 91  EFLEQDMDVVEVLTPTYTHAEIAIKALKAGKHVIVEKPIALTSEEAEKMIKEAEEQGLKL 150

Query: 121 FVGHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPADYWYWDESKSGGVIVDLGV 180
           FVGHVRRFDKRW QIK++IK+RNILPMQIRKIEVQHLPFPADYWYWDESKSGGVI+DLGV
Sbjct: 151 FVGHVRRFDKRWTQIKEVIKTRNILPMQIRKIEVQHLPFPADYWYWDESKSGGVIIDLGV 210

Query: 181 HVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWSYPMP 240
           HVTDFLRWFFESEP+EVFAVGKAIRGEARVNKT+DHVVMFIKFEG KTGIGEVSWSYPM 
Sbjct: 211 HVTDFLRWFFESEPVEVFAVGKAIRGEARVNKTYDHVVMFIKFEGNKTGIGEVSWSYPMT 270

Query: 241 PKYGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPRFSPMLSTFPQAFEAELRHFF 300
           PKYGVFYHHLDIIGKNGRIRYTP+DTPVVGV+KSSFEMPRFSPMLSTFPQAFEAELRHFF
Sbjct: 271 PKYGVFYHHLDIIGKNGRIRYTPLDTPVVGVIKSSFEMPRFSPMLSTFPQAFEAELRHFF 330

Query: 301 ECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKVEVN 341
           ECIKS+CEPVVTA+DALIAL+IAEKA+ESIKKGEPVKVEVN
Sbjct: 331 ECIKSNCEPVVTARDALIALQIAEKARESIKKGEPVKVEVN 371


>pir||H69216 3-chlorobenzoate-3,4-dioxygenase dyhydrogenase related protein -
           Methanobacterium thermoautotrophicum (strain Delta H)
           >gi|2621968|gb|AAB85373.1| (AE000863)
           3-chlorobenzoate-3,4-dioxygenase dyhydrogenase related
           protein [Methanobacterium thermoautotrophicum]
           Length = 318
           
 Score =  132 bits (330), Expect = 4e-30
 Identities = 99/338 (29%), Positives = 163/338 (47%), Gaps = 29/338 (8%)

Query: 4   KLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFL 63
           ++ VG+IG G +    H      L+  A ++AV DI +   +K   + +   +   +  L
Sbjct: 3   QINVGVIGVGAM-GYNHARVYYRLKN-ANLMAVSDIMKGTLQKVANKYDTVGYVDYENLL 60

Query: 64  E-QDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFV 122
           E  ++ VV +  PT  H  + ++AL+  KHV+VEKPIA T+EEAE M+K A  + LKL  
Sbjct: 61  EIPEIEVVSVCVPTTHHYNVVMDALEHDKHVLVEKPIAFTLEEAEDMVKTARKKGLKLGT 120

Query: 123 GHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPADYWYWDESKSGGVIVDLGVHV 182
           GHV RF+    + K++I++ +++   +     +  PFP         K  GV +DL +H 
Sbjct: 121 GHVERFNPAVQKAKELIEN-DVIGDVVSASAKRVGPFP------PRIKDVGVTIDLAIHD 173

Query: 183 TDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWSYPMPPK 242
            D + + F     EV+AV  +I  +    +  DH  +  KF+ G TGI EV+W  P   +
Sbjct: 174 LDVMHYLFSEPVAEVYAVMGSILEKC---EYEDHAEIMTKFKSGITGILEVNWLTPYKRR 230

Query: 243 YGVFYHHLDIIGKNG--RIRYTPMDTPVVGVVKSSFEMPRFSPMLSTFPQAFEAELRHFF 300
                  L I G +G   + Y      V G      ++    P+        + E++ F 
Sbjct: 231 ------KLAITGTDGIINVDYIDQRLDVYGKFAQDVDIKHEEPL--------KNEIKSFL 276

Query: 301 ECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKV 338
             + +  EP +T +D + AL+    A +S ++  PVKV
Sbjct: 277 MSVINDEEPEITGEDGIYALRTVLAAMKSAREHRPVKV 314


>pir||E75096 NADH-dependent dehydrogenase homolog. PAB0775 - Pyrococcus abyssi
           (strain Orsay) >gi|5458586|emb|CAB50074.1| (AJ248286)
           NADH-DEPENDENT DEHYDROGENASE HOMOLOG. [Pyrococcus
           abyssi]
           Length = 315
           
 Score =  132 bits (328), Expect = 7e-30
 Identities = 96/347 (27%), Positives = 165/347 (46%), Gaps = 46/347 (13%)

Query: 5   LKVGIIGCGNIFNLAHKPALKSLRTIAKV--VAVMDIDEEAARKAGKELNAKVFTSLDEF 62
           ++VG++G G +    H      L    KV  + V DI+ E A++  +    + F    E 
Sbjct: 1   MRVGVVGVGKM-GYHHARIYSELAKEGKVELIGVADINFERAKEVAETFKTRAFKDYREL 59

Query: 63  LEQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFV 122
           +++ ++ V I  PT  H E+ ++ ++    V+VEKPIA ++E A+++IK A+   + L V
Sbjct: 60  IKEGVDAVSIAVPTSLHREVTMDFIENEVSVLVEKPIAESIESAQEIIKAAKKMNVVLMV 119

Query: 123 GHVRRFDKRWIQIKDIIK-----------SRNILPMQIRKIEVQHLPFPADYWYWDESKS 171
           GHV RF+   +++K+ I+           ++ + PM  R  +V                 
Sbjct: 120 GHVERFNPAVLKLKETIERGMLGEIVTMTAKRVGPMVTRISDV----------------- 162

Query: 172 GGVIVDLGVHVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIG 231
            GVI+DL VH  D + +   S  IEV+A  + ++  A+V    D+ ++ + FE G  GI 
Sbjct: 163 -GVIIDLAVHDIDVMSFLTTSRVIEVYAKARNVKHPAKV---EDYALILLSFENGANGII 218

Query: 232 EVSWSYPMPPKYGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPRFSPMLSTFPQA 291
           E +   P   +       L+++G  G I Y       + +    +             + 
Sbjct: 219 ETNRLTPHKTR------TLNVVGTEG-IAYLDYINQELTLYNEEW----IYKAKINKEEP 267

Query: 292 FEAELRHFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKV 338
            + E+ HF EC+K   +P+V  ++ L ALK+A KA ES KK E V+V
Sbjct: 268 LKLEIEHFLECVKEGKKPLVGGEEGLHALKVAVKALESSKKDEVVRV 314


>pir||D72381 dehydrogenase - Thermotoga maritima (strain MSB8)
           >gi|4980919|gb|AAD35499.1|AE001720_13 (AE001720)
           dehydrogenase [Thermotoga maritima]
           Length = 334
           
 Score =  127 bits (317), Expect = 1e-28
 Identities = 99/342 (28%), Positives = 174/342 (49%), Gaps = 19/342 (5%)

Query: 5   LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNA-KVFTSLDEFL 63
           +++G+IG G I  + H   LK +   A + A+ D+ E+  R+  ++L   K +    E +
Sbjct: 1   MRIGVIGLGRIGTI-HAENLKMIDD-AILYAISDVREDRLREMKEKLGVEKAYKDPHELI 58

Query: 64  EQ-DMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFV 122
           E  +++ V + + T TH+EL I   KA KHV  EKP++L + + ++MI+E +  ++ LF 
Sbjct: 59  EDPNVDAVLVCSSTNTHSELVIACAKAKKHVFCEKPLSLNLADVDRMIEETKKADVILFT 118

Query: 123 GHVRRFDKRWIQIKDIIKSRNI-LPMQIRKIEVQHLPFPADYWYWDESKSGGVIVDLGVH 181
           G  RRFD+ + ++K+ +++  I  P  +R       P P DY       SGG+ +D+ +H
Sbjct: 119 GFNRRFDRNFKKLKEAVENGTIGKPHVLRITSRDPAPPPLDY----IRVSGGIFLDMTIH 174

Query: 182 VTDFLRWFFESEPIEVFAVGKAIRGEARVNKTH--DHVVMFIKFEGGKTGIGEVSWSYPM 239
             D  R+    E  EVFA G  +  E  + K    D  V+ ++F+ G  G+ + S     
Sbjct: 175 DFDMARYIMGEEVEEVFADGSVLVDE-EIGKAGDVDTAVVVLRFKSGALGVIDNS----R 229

Query: 240 PPKYGVFYHHLDIIGKNGRI-RYTPMDTPVVGVVKSSFEMPRFSP-MLSTFPQAFEAELR 297
              YG +   +++ G  GRI      +T VV   +      R+    L  +  ++  EL+
Sbjct: 230 RAVYG-YDQRIEVFGSKGRIFADNVRETTVVLTDEQGDRGSRYLYFFLERYRDSYLEELK 288

Query: 298 HFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKVE 339
            F + +KS   P V+ +D  +AL +   AK+S+++   VK+E
Sbjct: 289 TFIKNVKSGEPPAVSGEDGKMALLLGYAAKKSLEEKRSVKLE 330


>dbj|BAB04967.1| (AP001511) NADH-dependent dyhydrogenase [Bacillus halodurans]
           Length = 340
           
 Score =  126 bits (313), Expect = 4e-28
 Identities = 101/362 (27%), Positives = 163/362 (44%), Gaps = 53/362 (14%)

Query: 5   LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFLE 64
           L+V +IGCG+I    H P  +       +VAV D  EE A+K  K   A  +T   + LE
Sbjct: 4   LRVAVIGCGSIAQHRHLPEYEQ-NPHTTIVAVCDPVEERAKKVAKLYGAIAYTDHMQLLE 62

Query: 65  -QDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVG 123
            +++++V + TP   HA ++I+ALKAG HV+ EKP+A + EE E MIK AE   + L +G
Sbjct: 63  KEEIDLVSVCTPNAYHAPISIDALKAGTHVLCEKPMATSAEECEAMIKAAEEAGMCLMIG 122

Query: 124 HVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQH------LPFPADYWYWDESKSG-GVIV 176
           H +RF     + + +I + +I  +   +    H           + W++ + ++  G + 
Sbjct: 123 HNQRFVSSHEKARQLIATGDIGKIYSFRTTFGHGGPEGWSVDGENSWFFKKDQAFIGAMG 182

Query: 177 DLGVHVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWS 236
           DLGVH  D LR+    E +E   VG  +   A+     D+ V  +K E G  G    SWS
Sbjct: 183 DLGVHKADLLRYLLGEEVVE---VGAFVTTSAKQGDVDDNAVAILKTESGIVGTLTASWS 239

Query: 237 YPM-------------------PPKYGVFYHHLDIIGKNGR-IRYTPMDTPVVGVVKSSF 276
           Y                      P Y +  H+     KNG  ++Y       +G ++S+ 
Sbjct: 240 YVAKEDNSTILYGENAILRLEDDPHYSLIVHY-----KNGETVKYE------LGQIQSND 288

Query: 277 EMPRFSPMLSTFPQAFEAELRHFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPV 336
           E            Q     + HF   +    EP ++ ++   +L I   A E+ + G  +
Sbjct: 289 E----------GGQTDSRVIAHFVNSVLEGKEPPISGKEGYASLNIILAAMEASRTGRTI 338

Query: 337 KV 338
           K+
Sbjct: 339 KL 340


>gb|AAC23913.1| (AF039207) NADH-dependent dehydrogenase homolog [Listeria
           monocytogenes]
           Length = 358
           
 Score =  122 bits (304), Expect = 5e-27
 Identities = 106/358 (29%), Positives = 161/358 (44%), Gaps = 31/358 (8%)

Query: 5   LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKEL---NAKVFTSLDE 61
           LKVGIIGCG I N  H P+L      A++VA  DI  E A  A KE    NA V+T+  E
Sbjct: 3   LKVGIIGCGGIANGKHMPSLLKAEK-AEMVAFCDIVLEKAEAAAKEFGGENASVYTNYVE 61

Query: 62  FLE-QDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKL 120
            L+ + ++V+ + TP  +HAE++I A++AGKHV+ EKP+A T  EA+ MI+ AE    KL
Sbjct: 62  LLQDKSIDVIHVCTPNISHAEISIAAMEAGKHVMCEKPMAKTTAEAKSMIEAAERTGKKL 121

Query: 121 FVGHVRRFDKRWIQIKDIIKSRNILPMQIRKIE-VQHLPFPADYWYWD-ESKSGGVIVDL 178
            +G+  RF K    +  + ++  +  +   K + ++    P    + D E++ GG ++D+
Sbjct: 122 TIGYQNRFRKDSDYLHQVCENGELGDIYYAKAKAIRRRAVPTWGVFLDEEAQGGGPLIDI 181

Query: 179 GVHVTDFLRWFFESEPIEVFAVG----KAIRGEARVN----------KTHDHVVMFIKFE 224
           G H  D   W  ++   + + VG    K  + E   N             D    FI  E
Sbjct: 182 GTHALDLTLWMMDNYKPK-YVVGNSYHKLAKKENAANAWGSWDPNKFTVEDSAFGFITME 240

Query: 225 GGKTGIGEVSWSYPMPPKYGVFYHHLDIIGKNG------RIRYTPMDTPVVGVVKSSFEM 278
            G T + E SW+        V      + G  G       +R        +   K   E 
Sbjct: 241 NGATIVLEASWAL---NTLDVGEARTSLSGTEGGADMEDGLRINGEAHSQMYEKKIQLEA 297

Query: 279 PRFSPMLSTFPQAFEAELRHFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPV 336
                   T       E   +   I+ + +PVV    A++  +I E   ES K G+PV
Sbjct: 298 GGVDFYDGTGDDPALIEAGQWLGAIEKNTDPVVKPGQAIVVTQILEAIYESSKTGQPV 355


>pir||B72359 lipopolysaccharide biosynthesis protein BplA - Thermotoga maritima
           (strain MSB8) >gi|4981103|gb|AAD35670.1|AE001733_7
           (AE001733) lipopolysaccharide biosynthesis protein BplA
           [Thermotoga maritima]
           Length = 360
           
 Score =  120 bits (299), Expect = 2e-26
 Identities = 93/355 (26%), Positives = 166/355 (46%), Gaps = 33/355 (9%)

Query: 4   KLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNA------KVFT 57
           KL++ ++GCG I    H PAL   + + + VAV D+ EE A +A +          +  T
Sbjct: 2   KLRIALVGCGRIGQKKHVPALIETQDLFETVAVCDLVEERANRAAEHFEKSGLRRPETMT 61

Query: 58  SLDEFLE-QDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQ 116
           +  E L+ +D++V+ I T +  H ++ +EAL+AGKHV+VEKP+AL+ +   +M++ ++ +
Sbjct: 62  NYRELLKREDVDVISIATESGKHYQITMEALEAGKHVLVEKPMALSTKHMNEMVELSKQK 121

Query: 117 ELKLFVGHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPADY----WYWDESKSG 172
            LKL V    RF+    +++  + S     +    + V+       Y    W       G
Sbjct: 122 NLKLGVFFQNRFNPPVQEVRKKLDSGAFGKIFYASVAVRWNRNEDYYKQASWRGTWEMDG 181

Query: 173 GVIVDLGVHVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGE 232
           GV+++   H  D L+WF   E  E++  G          +  D     +KF+GGKTG+ E
Sbjct: 182 GVLMNQSTHAIDLLQWFLGGEIEEIY--GHIANTNHPYIEAEDEGFAIVKFKGGKTGLIE 239

Query: 233 VSWSYPMPPKYGVFYHHLD----IIGKNGRIRYTPMDTPVVGVVKSSFEMPRFSPML--- 285
            +          VF  +L+    I G+ G +    +   V  ++   FE     P +   
Sbjct: 240 AT--------SNVFPRNLEETLAIFGEKGTVVIGGI--AVNRILTWRFEGEEGHPFMNLP 289

Query: 286 ---STFPQAFEAELRHFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVK 337
              + +  + +   R F+E + +  +P ++ +D   A++I      S  +G PVK
Sbjct: 290 DPDTVYGDSHKYVYRDFYEAVTNDRKPYISGEDGKKAVEIVLGIYRSFLEGRPVK 344


>pir||B75025 NADH-dependent dyhydrogenase related protein PAB1139 - Pyrococcus
           abyssi (strain Orsay) >gi|5459154|emb|CAB50640.1|
           (AJ248288) NADH-dependent DYHYDROGENASE RELATED PROTEIN
           [Pyrococcus abyssi]
           Length = 335
           
 Score =  116 bits (287), Expect = 5e-25
 Identities = 100/348 (28%), Positives = 165/348 (46%), Gaps = 40/348 (11%)

Query: 15  IFNLAHKPALKSLRTI-----AKVVAVMD--IDEEAARKAGKELNAKVFTSLDEFL-EQD 66
           + + AH  AL+   TI     AK+VA+     +   A+   K+  AK +   ++ L ++ 
Sbjct: 6   VISYAHPHALRYAATIRANRRAKLVAISGDGANSGLAKIEAKKYGAKFYQDYEKLLRDES 65

Query: 67  MNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVGHVR 126
           +  V I   TY H E+AI A + GK +++EKPIALT+E+ ++++K A    +KL V    
Sbjct: 66  VEAVYIAIETYRHKEVAIRAAEEGKDILLEKPIALTLEDGKEIVKAARKAGVKLMVPFNP 125

Query: 127 RFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPA------DYWYWDESKS-GGVIVDLG 179
           RF +   + K++I+   I  ++      +++  P         W++D  KS GG  +D  
Sbjct: 126 RFTQPLQKAKEMIEKGEIGKLEYIYTISEYVKPPMFLEGIDTSWFFDIKKSGGGGFMDTA 185

Query: 180 VHVTDFLRWFFESEPIEVFA-VGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWSYP 238
            H  D L W  ESEPI V+A +G  I G     +  D     I+F+ G   +    W+ P
Sbjct: 186 PHGIDSLFWLTESEPIRVYADIGPKIWG----FQVDDIGTALIEFKNGVIAVLTAGWANP 241

Query: 239 MPPKYGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPRFSPMLSTFPQAF------ 292
               YG+   +  I+G +G +            ++S++  P F+       + F      
Sbjct: 242 KGYPYGLEIKYY-IVGDDGFLD-----------IRSAY--PDFTVYQDKTEKIFWERADV 287

Query: 293 EAELRHFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKVEV 340
           E  +  F + I+   EP +T +DAL  L +   A ES K G+ VKVE+
Sbjct: 288 EGIVNAFIDAIQQDKEPPITGEDALKNLAVVLAAYESSKTGKAVKVEL 335


>sp|O05389|YRBE_BACSU HYPOTHETICAL 37.8 KDA PROTEIN IN CSBX-NADA INTERGENIC REGION (ORF1)
           >gi|7429795|pir||D69972 opine catabolism homolog yrbE -
           Bacillus subtilis >gi|2635242|emb|CAB14737.1| (Z99118)
           similar to opine catabolism [Bacillus subtilis]
           >gi|6977802|emb|CAB75327.1| (Y15896) hypothetical
           protein [Bacillus subtilis]
           Length = 341
           
 Score =  113 bits (281), Expect = 2e-24
 Identities = 96/345 (27%), Positives = 159/345 (45%), Gaps = 17/345 (4%)

Query: 1   MPEKLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTS-- 58
           M +++  GIIG G I  L H   +  +  + K+ A+ DI     +        +  TS  
Sbjct: 1   MTKQIVTGIIGAGRIGKL-HVQNISRIPHM-KIKAISDIQASRIKSWADSHQIEYITSDY 58

Query: 59  LDEFLEQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQEL 118
            D   + D++ + I +PT  HA++  EA +A KH+  EKP++ +++E  + +       +
Sbjct: 59  RDLLHDPDIDAIFICSPTAVHAQMIKEAAEAKKHIFCEKPVSFSLDETSEALAAVRKHGV 118

Query: 119 KLFVGHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPADYWYWDESKSGGVIVDL 178
            L VG  RRFD  + +IK I+++  I    + KI  +  P P +  Y     SGG+ +D+
Sbjct: 119 TLQVGFNRRFDPHFKKIKTIVENGEIGTPHLLKITSRD-PEPPNIDY--VRTSGGLFMDM 175

Query: 179 GVHVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTH-DHVVMFIKFEGGKTGIGEVSWSY 237
            +H  D  R+   SE  EV+A G A+   +       D  V+ + FE G   + + S   
Sbjct: 176 SIHDFDMARYIMGSEVTEVYAKGAALVNPSFAELGDIDTAVITLTFENGAMAVIDNS--- 232

Query: 238 PMPPKYGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEM---PRFSPMLSTFPQAFEA 294
                YG +   +++ G  G           V V  + F M   P F   L  +  ++E 
Sbjct: 233 -RQAVYG-YDQRVEVFGTKGSAAADNSRPTTVEVSTADFVMKDKPHFF-FLERYKDSYEE 289

Query: 295 ELRHFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKVE 339
           E+  F E I ++ E   T  D L A +IA  A++S+  G PV +E
Sbjct: 290 EILRFAEAIGTNQETPCTGNDGLQAGRIARAAQQSLAFGMPVSIE 334


>sp|P40332|YISS_BACSU HYPOTHETICAL 37.5 KD PROTEIN IN DEGA-NPRB INTERGENIC REGION
           >gi|7429794|pir||B69838 myo-inositol 2-dehydrogenase
           homolog yisS - Bacillus subtilis
           >gi|1934841|emb|CAB07962.1| (Z93940) unknown [Bacillus
           subtilis] >gi|2145385|emb|CAA70648.1| (Y09476) YisS
           [Bacillus subtilis] >gi|2633420|emb|CAB12924.1| (Z99109)
           alternate gene name: yuxD, yucG~similar to myo-inositol
           2-dehydrogenase [Bacillus subtilis]
           Length = 342
           
 Score =  113 bits (281), Expect = 2e-24
 Identities = 95/350 (27%), Positives = 168/350 (47%), Gaps = 25/350 (7%)

Query: 1   MPEKLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLD 60
           M  +++  ++G G +    H   L +    AK+V V D  +  A +  +EL  + ++   
Sbjct: 1   MEHQVRCAVLGLGRL-GYYHAKNLVTSVPGAKLVCVGDPLKGRAEQVARELGIEKWSEDP 59

Query: 61  EFLEQD--MNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQEL 118
             + +D  ++ V I+TPT TH ++ I+A + GK + VEKP+ L++EE++   ++ +   +
Sbjct: 60  YEVLEDPGIDAVIIVTPTSTHGDMIIKAAENGKQIFVEKPLTLSLEESKAASEKVKETGV 119

Query: 119 KLFVGHVRRFDKRWIQIKDIIKSRNI-LPMQIRKIEVQHLPFPADYWYWDESKSGGVIVD 177
              VG +RRFD  +   K  I +  I  P+  +         PA++       SGG+ +D
Sbjct: 120 ICQVGFMRRFDPAYADAKRRIDAGEIGKPIYYKGFTRDQGAPPAEF----IKHSGGIFID 175

Query: 178 LGVHVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTH-DHVVMFIKFEGGKTGIGEVSWS 236
             +H  D  R+   +E   V   G+ +           D  + +I+F+ G  G  E S +
Sbjct: 176 CSIHDYDIARYLLGAEITSVSGHGRILNNPFMEQYGDVDQALTYIEFDSGAAGDVEASRT 235

Query: 237 YPMPPKYGVFYHHL--DIIGKNGRI---RYTPMDTPVVGVVKSSFE-MPRFSPMLSTFPQ 290
            P    YG   H +  ++IG  G I           ++    SSF+ +P F    + F +
Sbjct: 236 SP----YG---HDIRAEVIGTEGSIFIGTLRHQHVTILSAKGSSFDIIPDFQ---TRFHE 285

Query: 291 AFEAELRHFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKVEV 340
           A+  EL+HF EC+++   P+VT  DA I L++   A  S + G PV+++V
Sbjct: 286 AYCLELQHFAECVRNGKTPIVTDIDATINLEVGIAATNSFRNGMPVQLDV 335


>pir||E71201 probable glucose-fructose oxidoreductase - Pyrococcus horikoshii
           >gi|3258321|dbj|BAA31004.1| (AP000007) 335aa long
           hypothetical glucose-fructose oxidoreductase [Pyrococcus
           horikoshii]
           Length = 335
           
 Score =  112 bits (278), Expect = 5e-24
 Identities = 97/348 (27%), Positives = 166/348 (46%), Gaps = 40/348 (11%)

Query: 15  IFNLAHKPALKSLRTI-----AKVVAVMD--IDEEAARKAGKELNAKVFTSLDEFL-EQD 66
           I + AH  AL+   TI     AK+VA+     +   A+   K+  AK + + ++ L ++ 
Sbjct: 6   IISYAHPHALRYASTIRASRRAKLVAISGDGANSALAKVEAKKYGAKFYQNYEQLLKDKS 65

Query: 67  MNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVGHVR 126
           +  V I   TY H E+AI A + GK +++EKPIALT+E+ ++++K A    +KL V    
Sbjct: 66  VEAVYIAIETYRHKEVAIRAAEEGKDILLEKPIALTLEDGKEIVKAARKAGVKLMVPFNP 125

Query: 127 RFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPA------DYWYWDESKS-GGVIVDLG 179
           RF +   + K++I+S  I  ++      +++  P         W++D  KS GG  +D  
Sbjct: 126 RFTQPLQKAKEMIESGEIGKLEYIYTISEYVKPPMFLEGIDTSWFFDIRKSGGGGFMDTA 185

Query: 180 VHVTDFLRWFFESEPIEVFA-VGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWSYP 238
            H  D L W  ESEP++V+A +G  I G     +  D     I+F+     +    W+ P
Sbjct: 186 PHGIDSLFWLTESEPVKVYADIGSKIWG----FEVDDIGTALIEFKNNVIALLTAGWANP 241

Query: 239 MPPKYGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPRFSPMLSTFPQAF------ 292
               YG+   +  I+G +G +            +++++  P F+       + F      
Sbjct: 242 KGYPYGLEMKYY-IVGDDGFLD-----------IRTAY--PDFTVYQEKTEKIFWERADV 287

Query: 293 EAELRHFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKVEV 340
           E  +  F + I+   EP +T +DAL  L +   A ES K G+ VK+ +
Sbjct: 288 EGIINAFIDAIQQDREPPITGEDALKNLALVLAAYESSKTGKVVKINL 335


>gb|AAK43115.1| Dehydrogenase, putative [Sulfolobus solfataricus]
           Length = 319
           
 Score =  107 bits (265), Expect = 2e-22
 Identities = 93/331 (28%), Positives = 161/331 (48%), Gaps = 38/331 (11%)

Query: 5   LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAK-VFTSLDEFL 63
           +K+ ++GC   F   H  A++++  I   V     +EE AR+  KE NA+  FT  ++ +
Sbjct: 1   MKIAVVGCDG-FGKVHLRAMRNISGIEYYV--FSRNEEKARECMKEFNAEGYFTRYEDVI 57

Query: 64  EQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVG 123
           + ++++V++L     H  + + A+KAGKH+++EKPIA T+EEA  +I  +++ + K  V 
Sbjct: 58  KSNVDIVDLLVSHDQHYPMGVMAMKAGKHLMLEKPIARTIEEAMGLINTSKDTKRKFMVL 117

Query: 124 HVRRFDKRWIQIKDII-KSRNILPMQIRKIEVQHLPFPADYWYWDESKSGGVIVDLGVHV 182
               F+    + K+++ +  N+  + +R I   HL  P  +    E   GG ++D GVH 
Sbjct: 118 EQFYFESSVRKAKELLPRLGNLSLIIVRSI---HLYQPKGWRREKEKMGGGALIDGGVHF 174

Query: 183 TD-FLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWSYPMPP 241
            D  L    E E +     GK   G     +  D  +  ++F  G  G+   SW+ P PP
Sbjct: 175 IDTLLNLGGEYESVR-GVCGKYFSG----IEGEDLTLATLRFRKGHLGLLMYSWTTPNPP 229

Query: 242 KYGVFYHHLDIIGKNGRIRYTPMDTPVVGVV-----------KSSFEMPRFSPMLSTFPQ 290
           K   F    +I G+NG I   P +T V+G             +   E+ + +P+      
Sbjct: 230 KVPAF----EIYGENGSIIEDP-NTRVMGKAYGDLILNVDGKEERIEVEKVNPI------ 278

Query: 291 AFEAELRHFFECIKSSCEPVVTAQDALIALK 321
             E E+R F + +K++ E  +  + AL  LK
Sbjct: 279 --EEEIRGFVKAVKNNTEVPMPPEIALRDLK 307


>gb|AAK43149.1| Dehydrogenase, putative [Sulfolobus solfataricus]
           Length = 371
           
 Score =  106 bits (261), Expect = 5e-22
 Identities = 96/361 (26%), Positives = 166/361 (45%), Gaps = 30/361 (8%)

Query: 1   MPEKLKVGIIGCGNIFNLAHKPALKSLRT---IAKVVAVMDIDEEAARKAGKELNAKVFT 57
           M +++ V ++G G+I    H  ALK L       K+VAV+D  +  A K G E     +T
Sbjct: 16  MSKRIGVAVVGLGSI-GKTHVKALKDLEKETEFVKLVAVVDQIKAIAEKIGSEYGTPYYT 74

Query: 58  SLDEFLEQ-DMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQ 116
           ++DE L   +++V+ I TP+Y HA  AI A++ GKHVIVEKP+A T+  A +M+  AE  
Sbjct: 75  TIDEVLRNSEVDVISIATPSYLHAPQAILAIEYGKHVIVEKPMATTLAGAREMVSRAERN 134

Query: 117 ELKLFVGHVRRFDKRWIQIK-DIIKSRNILPMQIRKIEVQHLPFPADYWYWDE------- 168
           E+KL V    R+     ++K DI+K   +  + + + E++       Y+  DE       
Sbjct: 135 EVKLGVIFQERYAPDIRRLKNDILK--ELGRIYLIESELKWYRDMKGYYKRDEIARSWRG 192

Query: 169 ---SKSGGVIVDLGVHVTDFLRWF-FESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFE 224
              ++ GGV+ + G+H  D + W   E E +  F       G     +  D  V  ++++
Sbjct: 193 MWNTEGGGVMTNQGIHTIDLMIWLNGEVEEVSGFVDNLTHDG----IEVEDTAVAIMRYK 248

Query: 225 GGKTGIGEVSWSYPMPPKYGVFYHHLDIIGKNGRIRYTPMDTPVV---GVVKSSFEMPRF 281
            G   +G +S +  M P     Y  + + G NG +  T      V   G ++ S     +
Sbjct: 249 NG--ALGTISQTVSMKPT-TYQYRKIRVNGSNGFVEITDGSLSTVAIEGKIEESKSSVEY 305

Query: 282 SPMLSTFPQAFEAE-LRHFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKVEV 340
                  P     E LR F   +    +  +  ++ + +L++ +    S    + VK+ +
Sbjct: 306 KKETIAQPGNLHKELLRDFLRALSEDNDFPINGKEGMKSLEVIKAVYLSSVNRQVVKLPL 365

Query: 341 N 341
           +
Sbjct: 366 D 366


>gb|AAC01706.1| (AF040570) unknown [Amycolatopsis mediterranei]
           Length = 342
           
 Score =  104 bits (256), Expect = 2e-21
 Identities = 90/343 (26%), Positives = 148/343 (42%), Gaps = 28/343 (8%)

Query: 4   KLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFL 63
           +L+V +IG G I  L H  A        +V +    D+  +R+   E  AK   SL+E L
Sbjct: 18  QLEVALIGAGLIARL-HLEAWLGAGAAVRVYS----DDGRSRELAAEFGAKAAGSLEEAL 72

Query: 64  EQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVG 123
           +   + V+I TPT +H E+A+ A+ AG  V+ EKP+A + EEAE+++  AE   ++L+  
Sbjct: 73  D-GADAVDICTPTASHHEIALTAIAAGVGVVCEKPLAASAEEAEEIVTAAERAGVRLYAA 131

Query: 124 HVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPADYWYWDESKSGGVIVDLGVHVT 183
           H  RF   + ++ +++ S  +    + +        P  +     ++SGG++ D  +H  
Sbjct: 132 HDVRFAAPYARLHELVASGRLGEGALGRFSFSAY-HPRPWTGHASARSGGILTDQLLHGA 190

Query: 184 DFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHV---VMFIKFEGGKTGIGEVSWSYPMP 240
           D   W F     +V  V    +G+         V      +    G        W+    
Sbjct: 191 DLAHWVFG----DVVRVHACYQGDIATPAPEGAVATGTAVLTHASGAISQVVSRWTATPR 246

Query: 241 PKYGVFYHHLDIIGKNGRIRYT---PMDTPVVGVVKSSFEMPRFSPMLSTFPQAFEAELR 297
           P   V +H   + G  G + Y    P +  VV     +F            P  F+ E+R
Sbjct: 247 PPVRVAFH---VSGTGGSVSYDSEWPQEVRVVDGGAGNFAYGG--------PSVFDTEMR 295

Query: 298 HFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKVEV 340
            F        EP + A+DAL A++I   A ES   G  V++ V
Sbjct: 296 EFATAFAGGPEPRIGAKDALAAVRIIHAAAESAWTGRAVELPV 338


>gb|AAK43117.1| Dehydrogenase, putative [Sulfolobus solfataricus]
           Length = 355
           
 Score =  104 bits (256), Expect = 2e-21
 Identities = 96/359 (26%), Positives = 166/359 (45%), Gaps = 27/359 (7%)

Query: 4   KLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFL 63
           K++ GIIG G      H   L  L+   ++VAV D+ +E   +   + N K +    E +
Sbjct: 2   KIRYGIIGVGGHGKNRHLIPLIKLKNKVEIVAVADVKKERCEEVSSQFNIKCYLDYMEMV 61

Query: 64  EQD-MNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFV 122
           E++ +N V I+TPT  H+ +AI  L  G +V+V+KP+   +EE ++++  A N+ LKL V
Sbjct: 62  EKESLNAVSIVTPTGLHSRIAINVLNKGVNVLVDKPLGSNLEEVKEVVNTARNKGLKLMV 121

Query: 123 GHVRRFDKRWIQIKDIIKSRNI-LPMQIRKIEVQHLPFPADYWYWDESKSG--GVIVDLG 179
           G+  RF       K+II +  +  P       V+    P    + D++ SG  G ++D+G
Sbjct: 122 GYWSRFSPALQYGKEIIHNGLLGEPYVAYGYLVRRRGIPGIPTFIDKTLSGGRGALLDIG 181

Query: 180 VHVTDFLRWFFE-SEPIEVFAVGKA------IRGEARVN---------KTHDHVVMFIKF 223
            ++ D L    +  +PI V  +GK       ++ E + N            D+ V  +K 
Sbjct: 182 CYLIDNLLSLLKFRKPISV--MGKVYTKFGNVKEEVKFNWGSWDPENFSLDDYAVGLVKL 239

Query: 224 EGGKTGIGEVSWSYPMPPKYGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFE--MPRF 281
           EG  + I EV WS  +       Y  + I+G  G I  +  +  V     S  E  +   
Sbjct: 240 EGDVSLILEVGWSANVSHVEEKSY--VRILGDKGGIEGSGHEAIVDISFHSRTENFLTDT 297

Query: 282 SPMLSTFPQAFEAELRHFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKVEV 340
            P+L      FE  +  F + I +  EP +T ++++    I +   +S  + + VK+ +
Sbjct: 298 KPVLRKVDPYFEM-INAFVDSILTDREPPITGEESVTLHSIIDGIYKSSTEDKEVKISL 355


>emb|CAB88961.1| (AL353864) putative oxidoreductase. [Streptomyces coelicolor A3(2)]
           Length = 358
           
 Score =  103 bits (254), Expect = 3e-21
 Identities = 93/338 (27%), Positives = 151/338 (44%), Gaps = 14/338 (4%)

Query: 5   LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFLE 64
           +++GI+G G I    H   L  L ++  +V V D   +AA+ A +   A+V  S +    
Sbjct: 25  MRIGILGLGRI-GAFHAETLAGLDSVGSLV-VADPFADAAKAAAERFGAEVADSPEAVFA 82

Query: 65  QDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVGH 124
             ++ V I   T  H +L + A++AG  V  EKP+A T+ E  +++K    +++ + +G+
Sbjct: 83  AGVDGVVIAAATDAHPDLILAAVEAGVPVFCEKPVARTMAEGVEVLKALAGRDVPVQIGY 142

Query: 125 VRRFDKRWIQIKDIIKSRNILPMQ-IRKIEVQHLPFPADYWYWDESKSGGVIVDLGVHVT 183
            RRFD  +   +  ++S  + P+  +R   +   P PA Y     + SGG+  D  VH  
Sbjct: 143 QRRFDTGFAAARAAVRSGELGPLHTVRSTTLDPAPPPAAY----VAASGGIFRDCSVHDF 198

Query: 184 DFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWSYPMPPKY 243
           D +RW    E  EV+AVG   RG   + +  D              +  VS S      Y
Sbjct: 199 DSIRWVTGREVGEVYAVG-GNRGADYIREAGDADTTGAVLTLDDGTVAVVSNSRHNARGY 257

Query: 244 GVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPRFSP---MLSTFPQAFEAELRHFF 300
            V    ++I G +  I     D   +  V+     P  +P    +  F  A+ AEL  F 
Sbjct: 258 DV---RMEIHGFDDSIAVGLEDRLPLRSVEPGVTFPAGTPHDFFMDRFTAAYRAELTAFT 314

Query: 301 ECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKV 338
           E +  +     T +DAL A  IAE    S+ +  PV +
Sbjct: 315 EVVAGARPSPCTVEDALEAGWIAEACTLSLHEHRPVTI 352


>gb|AAC31183.1| (AF076240) putative NADH-inositol dehydrogenase MocA [Rhizobium
           leguminosarum bv. viciae]
           Length = 306
           
 Score = 97.5 bits (239), Expect = 2e-19
 Identities = 89/330 (26%), Positives = 142/330 (42%), Gaps = 35/330 (10%)

Query: 4   KLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFL 63
           + ++G+IG G +  +  + A +SL  + +V AV++    A R A +    K + + DE +
Sbjct: 3   EFRLGLIGAGRMGQVHLRAASESL--LVEVTAVVE-PVAATRLALERSGIKTYKTADEMI 59

Query: 64  EQ-DMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFV 122
           +  +++ V I TP+ TH E        G  ++ EKP  +T EEA K  + AE  ++ L +
Sbjct: 60  DAGEIDGVLIATPSKTHVENITNIAARGLPILCEKPCGVTAEEARKAAEAAEQFKVHLQI 119

Query: 123 GHVRRFDKRWIQIKDIIKSRNI-LPMQIRKIEVQHLPFPADYWYWDESKSGGVIVDLGVH 181
           G+ RRF     +++  I+S  +  P  I   +    P  A +     +  GG ++D+GVH
Sbjct: 120 GYWRRFVPELEKLRQNIRSGLLGEPYLISCFQWDETPPAASF----RATGGGALIDMGVH 175

Query: 182 VTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWSYPMPP 241
             D +RW    EP              +V    D V +     GG  G+G VS     PP
Sbjct: 176 EFDQMRWLTGQEPSNFRVAASKTTFAGKVEGDPDAVQLLCDLSGG--GVGLVSLGRRFPP 233

Query: 242 KYGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPRF---SPMLSTFPQAFEAELRH 298
               +     + G +G                  FE  RF       + F  A  ++L  
Sbjct: 234 GDACW---AQVFGTSG------------------FEEVRFFWPPNGEAVFLNALRSQLED 272

Query: 299 FFECIKSSCEPVVTAQDALIALKIAEKAKE 328
           F +  +       TAQDA+ AL IAE A E
Sbjct: 273 FVQAARGGASQGATAQDAVTALAIAEAATE 302


>sp|O68965|MI2D_RHIME MYO-INOSITOL 2-DEHYDROGENASE >gi|3088561|gb|AAC70005.1| (AF059313)
           myo-inositol dehydrogenase [Sinorhizobium meliloti]
           Length = 330
           
 Score = 94.8 bits (232), Expect = 1e-18
 Identities = 86/339 (25%), Positives = 143/339 (41%), Gaps = 17/339 (5%)

Query: 5   LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFLE 64
           ++ G++G G I  +  K    S    A++VAV D    AA         +V T       
Sbjct: 3   VRFGLLGAGRIGKVHAKAV--SGNADARLVAVADAFPAAAEAIAGAYGCEVRTIDAIEAA 60

Query: 65  QDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVGH 124
            D++ V I TPT THA+L     +AGK +  EKPI L  E     +K   + + KL VG 
Sbjct: 61  ADIDAVVICTPTDTHADLIERFARAGKAIFCEKPIDLDAERVRACLKVVSDTKAKLMVGF 120

Query: 125 VRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPF-PADYWYWDESKSGGVIVDLGVHVT 183
            RRFD  ++ ++  I    I  +++  I  +     P DY      +SGG+  D+ +H  
Sbjct: 121 NRRFDPHFMAVRKAIDDGRIGEVEMVTITSRDPSAPPVDY----IKRSGGIFRDMTIHDF 176

Query: 184 DFLRWFFESEPIEVFAVGKAIRGEARVNK-THDHVVMFIKFEGGKTGIGEVSWSYPMPPK 242
           D  R+    EP+ V A    +  +A  +   +D V + ++   GK  I   S        
Sbjct: 177 DMARFLLGEEPVSVTATAAVLIDKAIGDAGDYDSVSVILQTASGKQAIIANS----RRAT 232

Query: 243 YGVFYHHLDIIGKNGRIRYTPMDTPV---VGVVKSSFEMPRFSPMLSTFPQAFEAELRHF 299
           YG +   +++ G  G +       PV   +         P     ++ + +A+  E+  F
Sbjct: 233 YG-YDQRIEVHGSKGAVA-AENQRPVSIEIATGDGYTRPPLHDFFMTRYTEAYANEIESF 290

Query: 300 FECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKV 338
              I+   E   +  D L AL +A+ A  S+ +   + +
Sbjct: 291 IAAIEKGAEIAPSGNDGLAALALADAAVRSVAEKRQISI 329


>emb|CAB60174.1| (AL132824) putative dehydrogenase [Streptomyces coelicolor]
           Length = 337
           
 Score = 93.6 bits (229), Expect = 3e-18
 Identities = 89/341 (26%), Positives = 150/341 (43%), Gaps = 20/341 (5%)

Query: 5   LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFLE 64
           +++G+IG G I    H   L   R +  ++ + D D   A++    L       +DE  +
Sbjct: 1   MRIGVIGTGRI-GTVHANTLSRHRDVGSLI-LTDADIARAQELAHRLGETAAPGVDEIFQ 58

Query: 65  QDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVGH 124
             ++ V I T T  HAEL   A ++G  V  EKPIAL +    + I E E     L +G 
Sbjct: 59  WGVDAVVITTATPAHAELIGRAARSGLPVFCEKPIALDLPGTLQAIAEVEAAGTVLQMGF 118

Query: 125 VRRFDKRWIQIKDIIKSRNILPMQ-IRKIEVQHLPFPADYWYWDESKSGGVIVDLGVHVT 183
            RRFD  +   ++ ++S  +  +  +R +     P PADY      +SGG+  D  +H  
Sbjct: 119 QRRFDTGYTGAREAVRSGRLGRLHTVRAVTSDQTPPPADYL----PQSGGLYRDTLIHDF 174

Query: 184 DFLRWFFESEPIEVFAVGK-AIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWSYPMPPK 242
           D LRW    E ++V+A G  A     R     D   + +  + G       +        
Sbjct: 175 DVLRWVTGREVVDVYAAGSDAGPPMFRAADDVDTGAVLLTLDDGTLATATAA------RL 228

Query: 243 YGVFYH-HLDIIGKNGRIRYTPMD-TPVVGVVKS---SFEMPRFSPMLSTFPQAFEAELR 297
            G  Y   +++ G+  +I     D TP+     +   + + P ++  +  F  A+EAEL 
Sbjct: 229 NGAGYDVRMELAGELDQIVVGLDDRTPIASTEPTGPPAADKP-WTGFVERFGPAYEAELT 287

Query: 298 HFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKV 338
            F + ++         ++AL AL+IAE    S ++  PV++
Sbjct: 288 TFVQVVRGERANPCDGREALQALRIAEACDVSRRERRPVRL 328


>dbj|BAB05884.1| (AP001514) unknown conserved protein [Bacillus halodurans]
           Length = 348
           
 Score = 93.6 bits (229), Expect = 3e-18
 Identities = 83/352 (23%), Positives = 159/352 (44%), Gaps = 25/352 (7%)

Query: 3   EKLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAK-VFTSLDE 61
           +KL+VGIIG G I    H P+  SL+   ++VA+ D+  + A+ A ++ +   V+     
Sbjct: 4   KKLRVGIIGAGGIARTVHIPSYLSLKDQVELVAITDVQPKHAQAAAEQFSIPYVYNDASR 63

Query: 62  FLEQ-DMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKL 120
            +++ +++ V I TP   H EL IEAL AG HV+ EKP A+TVE+A++M   A+     L
Sbjct: 64  MMQEVELDAVSICTPNAFHRELTIEALHAGCHVLCEKPPAITVEDAKQMEAAAKETGNLL 123

Query: 121 FVGHVRRFDKRWIQIKDII---KSRNILPMQIRKIEVQHLPFPADYWYWDESKSGGVIVD 177
             G   R       +K  +   +   I  ++++ I  + +P    +    E + GG ++D
Sbjct: 124 TYGFHYRHSPEVETLKRFVDEGELGEIYHVRVQAIRRRGIPGWGVFTN-KELQGGGPLID 182

Query: 178 LGVHVTDFLRWFFE-SEPIEVFA---------VGKAIRGEARVNK--THDHVVMFIKFEG 225
           +GVH+ D   +     EP  +            G  + GE    +    D  V  I F+ 
Sbjct: 183 IGVHMLDTALYVMGFPEPATILGQTHRKIGTKEGVGLLGEWNWQQFSIEDMAVGMITFKN 242

Query: 226 GKTGIGEVSWSYPMPPKYGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPRFSPML 285
           G +   E +++  +  +    + ++   G  G     P+        +    +   +P+ 
Sbjct: 243 GASLTIETAFAANVKEQ---DHMNVSFFGDKGGADLFPLSI----YQEKHRTLLDITPVY 295

Query: 286 STFPQAFEAELRHFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVK 337
                  E E++HF +C     +P+ T +  ++  ++ +   +S + G+ ++
Sbjct: 296 LPTYNHHEREIKHFVDCCFRLEQPLATPEQGIVIQRLIQGLYQSAESGKAIQ 347


>pir||S76068 hypothetical protein - Synechocystis sp. (strain PCC 6803)
           >gi|1001423|dbj|BAA10046.1| (D63999) hypothetical
           protein [Synechocystis sp.]
           Length = 364
           
 Score = 93.2 bits (228), Expect = 4e-18
 Identities = 77/334 (23%), Positives = 141/334 (42%), Gaps = 27/334 (8%)

Query: 3   EKLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEF 62
           + +++G+IG GN+    H   + SL    + V + D++ E       +     F    E 
Sbjct: 22  QPIRIGVIGVGNMGQ--HHTRVLSLMKDVEFVGIADVNVERGLDTASKYRVHFFEDYQEM 79

Query: 63  LEQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFV 122
           L   ++ V +  PT  H ++ +  L+   H ++EKPIA ++ EAE ++  A +    L V
Sbjct: 80  LPH-VDAVCVAVPTRLHHDVGMNCLQNNVHTLIEKPIAASIAEAESLVNAAADANCILQV 138

Query: 123 GHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPADYWYWDESKSGGVIVDLGVHV 182
           GH+ RF+  ++++  I+K+  +L ++  ++            Y   +    V++DL +H 
Sbjct: 139 GHIERFNPAFLELTKILKTEELLAIEAHRMSP----------YSQRANDVSVVLDLMIHD 188

Query: 183 TDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWSYPMPPK 242
            D L     SE +++ A G    G   +    D+V   + F  G   +  ++ S     K
Sbjct: 189 IDLLLELVGSEVVKLSASGSRASGSGYL----DYVTATLGFSSGI--VATLTASKVTHRK 242

Query: 243 YGVFYHH-------LDIIGKNGRI-RYTPMDTPVVGVVKSSFEMPRFSPMLSTFPQAFEA 294
                 H        D +     I R T  D           +      + ++  +   A
Sbjct: 243 IRSIAAHCKNSLTEADFLNNEILIHRQTTADWSADYGQVLYRQDGLIEKVYTSNIEPLHA 302

Query: 295 ELRHFFECIKSSCEPVVTAQDALIALKIAEKAKE 328
           EL HF  C++   +P V  + AL ALK+A   +E
Sbjct: 303 ELEHFIHCVRGGDQPSVGGEQALKALKLASLIEE 336


>pir||A69834 conserved hypothetical protein yhjJ - Bacillus subtilis
           >gi|2226182|emb|CAA74472.1| (Y14081) hypothetical
           protein [Bacillus subtilis] >gi|2633389|emb|CAB12893.1|
           (Z99109) similar to hypothetical proteins [Bacillus
           subtilis]
           Length = 350
           
 Score = 93.2 bits (228), Expect = 4e-18
 Identities = 63/197 (31%), Positives = 107/197 (53%), Gaps = 16/197 (8%)

Query: 6   KVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFLEQ 65
           K+GIIG G I   AH  AL +++  A++V V DI+++ A    K    K F ++DE ++ 
Sbjct: 3   KIGIIGAGGIAR-AHATALSTIKN-AELVGVYDINQQNAESFVKTFGGKSFENVDELIDA 60

Query: 66  DMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVGHV 125
              ++ + +P + H E A++AL   KHV+ EKP+A+++EEA  M   AE   ++  +G  
Sbjct: 61  SEGLI-VASPNFCHKEHALQALGKHKHVLCEKPMAISLEEASIMKDTAERLSVRASMG-- 117

Query: 126 RRFDKRWIQIKDIIKS-------RNILPMQIRKIEVQHLPFPADYWYWD--ESKSGGVIV 176
             F+ R++   +I+KS        NIL +++   +   L      W  D    K+ G + 
Sbjct: 118 --FNYRYLSYVNILKSLIINNELGNILSIKVHFKKNSALRRKKFTWRDDANSKKTSGSLG 175

Query: 177 DLGVHVTDFLRWFFESE 193
           DLG+H+ D + + FES+
Sbjct: 176 DLGIHLIDMVWYLFESD 192


>dbj|BAB06035.1| (AP001515) myo-inositol 2-dehydrogenase [Bacillus halodurans]
           Length = 348
           
 Score = 90.1 bits (220), Expect = 3e-17
 Identities = 95/337 (28%), Positives = 156/337 (46%), Gaps = 23/337 (6%)

Query: 5   LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKE--LNAKVFTSLDEF 62
           L+ G+IG G I    H   +++  +  K+VAV D+++EAA++   +  L A V+   D  
Sbjct: 3   LRFGVIGTGAI-GREHMKRIENKLSGGKIVAVTDMNQEAAKQVVTQMKLEADVYPD-DRS 60

Query: 63  LEQDMNVVEILTPTY--THAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKL 120
           L    NV  +L  ++   H    + A++AGK+V VEKP+A T E   K+IK   N   +L
Sbjct: 61  LVAADNVDAVLVTSWGPAHEANVLAAIEAGKYVFVEKPLATTAEGCMKIIKAEMNHGKRL 120

Query: 121 F-VGHVRRFDKRWIQIKDIIKSRNI-LPMQIRKIEVQHLPFPADYWYWDESKSGGVIVDL 178
             VG +RR+DK ++Q+K  I    I  P+ +R     H        Y D+      I D 
Sbjct: 121 VQVGFMRRYDKGYVQLKKAIDDHFIGEPLMVR---CAHRNPEVGESYIDDM----AIHDT 173

Query: 179 GVHVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWSYP 238
            +H  D L W  + E  E  +V    + +  +    D  V+ ++ +GG     EV     
Sbjct: 174 LIHEIDVLHWLIDDE-YESVSVSFPKKTKHALPHLRDPRVVTLETKGGVLITAEVF---- 228

Query: 239 MPPKYGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPRFSPMLSTFPQAFEAELRH 298
           +  KYG +    ++I + G I   P    +    +++            F +A++ EL+H
Sbjct: 229 VNCKYG-YDIQCEVIREEG-IASLPEVDSISFRKRATLGTNILMDWKQRFIEAYDVELQH 286

Query: 299 FFECIKSSCEPV-VTAQDALIALKIAEKAKESIKKGE 334
           F + IK S EP    A D  +A   A+ A ++   G+
Sbjct: 287 FIDSIKQSGEPSGPNAWDGYVAAITADAALKASNSGQ 323


>sp|P26935|MI2D_BACSU MYO-INOSITOL 2-DEHYDROGENASE >gi|80338|pir||JH0511 myo-inositol
           2-dehydrogenase (EC 1.1.1.18) iolG - Bacillus subtilis
           >gi|143086|gb|AAA22543.1| (M76431) inositol
           dehydrogenase [Bacillus subtilis]
           >gi|709987|dbj|BAA03296.1| (D14399) myo-inositol
           dehydrogenase [Bacillus subtilis]
           >gi|2636516|emb|CAB16006.1| (Z99124) myo-inositol
           2-dehydrogenase [Bacillus subtilis]
           Length = 344
           
 Score = 89.7 bits (219), Expect = 4e-17
 Identities = 91/343 (26%), Positives = 165/343 (47%), Gaps = 23/343 (6%)

Query: 5   LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKE--LNAKVFTSLDEF 62
           L++G+IG G I    H   + +  + A++VAV D+++EAA+K  ++  LNA V+ + D+ 
Sbjct: 3   LRIGVIGTGAI-GKEHINRITNKLSGAEIVAVTDVNQEAAQKVVEQYQLNATVYPN-DDS 60

Query: 63  LEQDMNVVEILTPTY--THAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKL 120
           L  D NV  +L  ++   H    ++A+KA K+V  EKP+A T E   ++++E      +L
Sbjct: 61  LLADENVDAVLVTSWGPAHESSVLKAIKAQKYVFCEKPLATTAEGCMRIVEEEIKVGKRL 120

Query: 121 F-VGHVRRFDKRWIQIKDIIKSR-NILPMQIRKIEVQHLPFPADYWYWDESKSGGVIVDL 178
             VG +RR+D  ++Q+K+ + +  N  P+ I        P   D +  D +     +VD 
Sbjct: 121 VQVGFMRRYDSGYVQLKEALDNHVNGEPLMIHC--AHRNPTVGDNYTTDMA-----VVDT 173

Query: 179 GVHVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWSYP 238
            VH  D L W   ++  E   V    + +  +    D  ++ I+ +GG     E+     
Sbjct: 174 LVHEIDVLHWLV-NDDYESVQVIYPKKSKNALPHLKDPQIVVIETKGGIVINAEIY---- 228

Query: 239 MPPKYGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPRFSPMLSTFPQAFEAELRH 298
           +  KYG +    +I+G++G I+  P  + +    +  F           F  A++ E++ 
Sbjct: 229 VNCKYG-YDIQCEIVGEDGIIK-LPEPSSISLRKEGRFSTDILMDWQRRFVAAYDVEIQD 286

Query: 299 FFECIKSSCE-PVVTAQDALIALKIAEKAKESIKKGEPVKVEV 340
           F + I+   E    TA D  IA    +   ++ + G+  KVE+
Sbjct: 287 FIDSIQKKGEVSGPTAWDGYIAAVTTDACVKAQESGQKEKVEL 329


>gb|AAK43113.1| Dehydrogenase, putative [Sulfolobus solfataricus]
           Length = 363
           
 Score = 88.9 bits (217), Expect = 8e-17
 Identities = 92/360 (25%), Positives = 152/360 (41%), Gaps = 36/360 (10%)

Query: 5   LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFLE 64
           +K+GI+G G     AH PAL  L    KV    DIDE+  +   ++   K +    E L 
Sbjct: 4   MKLGIVGLGGWVTGAHIPALTDLGI--KVDYCADIDEKRVKDLSQKTGCKGYLDYKEMLR 61

Query: 65  -QDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVG 123
            ++ ++V +  P   HA +A++A+    +V VEKP+A + +EA  +++ +  +   L VG
Sbjct: 62  NENPDLVLVAVPHSLHAIIALDAINNDANVYVEKPMATSFQEALTLVEASRKRNKILVVG 121

Query: 124 HVRRFDKRWIQIKDIIKS---RNILPMQIRKIEVQHLPFPADYWYWDESKSGGVIVDLGV 180
           H  RF+   +  K +I+      I  M+   I  + +P    +   D +K GG + D+G 
Sbjct: 122 HENRFNPAMLIAKKLIRGGEVGKIYHMRGFYIRQRGIPTSPTFIKKDLAK-GGAVFDIGT 180

Query: 181 HVTDFLRWFFESEPIEVFAVGKAIRGEARVN----------------KTHDHVVMFIKFE 224
           H+ D L  F    P      GK     +                   +  D    F+K  
Sbjct: 181 HIIDLL-LFLSDFPTPKSVTGKTYNAFSEDKTKFSAYPSPNLPNFKVEVEDFGSAFLKLG 239

Query: 225 GGKTGIGEVSW-SYPMPPKYGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKS-SFEMPRFS 282
              +   EVSW SY    K  V      I+G NG I    +D  V+  +++   E+   S
Sbjct: 240 DEISAYVEVSWASYIKENKMEVV-----ILGDNGGIH---IDNGVLNFMRNIEDELFISS 291

Query: 283 PMLSTFPQAFEAELRHFFECIKSSCE--PVVTAQDALIALKIAEKAKESIKKGEPVKVEV 340
           P+       +    R   E I       P+ +A+   I + I E   +S  +G  VK+++
Sbjct: 292 PLTQQKGSVYREVWRTVMESISKGFPEYPLCSAEQGAIGVAILESIYKSALEGREVKIDI 351


>emb|CAC11912.1| (AL445065) hypothetical protein [Thermoplasma acidophilum]
           Length = 322
           
 Score = 88.2 bits (215), Expect = 1e-16
 Identities = 71/260 (27%), Positives = 125/260 (47%), Gaps = 21/260 (8%)

Query: 5   LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAK-VFTSLDEFL 63
           + V +IG GN F   H    ++ R +    +V D + +      ++   +  ++ +   L
Sbjct: 6   MSVLLIG-GNGFAKVHA---ETYRRLGIEFSVYDRNPQVLEMYRRDYGVRETYSDMAAAL 61

Query: 64  EQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVG 123
           + D + V+I+ P   H E+A++A++ GKHV+VEKP+   ++EA K+I +A+ + LK  V 
Sbjct: 62  DADNDAVDIVLPHNLHYEVAMKAIEKGKHVLVEKPVTGRIDEAVKIINQAKKKRLKFMVA 121

Query: 124 HVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPADYWYWDESK-SGGVIVDLGVHV 182
               FD  + +  +I++S  I  ++   +  Q   + A  W   +++  GG ++D GVH 
Sbjct: 122 EQFYFDPSFRKALEIVQSGKIGDVRTVIVRDQQ-RYDAPGWRSRKNEMMGGSLIDGGVHF 180

Query: 183 TDFLRWF---FESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWSYPM 239
            +    F   ++S     +  G +I GE       D+      FE    GI   SWSY  
Sbjct: 181 LEIFLDFGGQWKSISAHNYKGGTSIEGE-------DNTAALFTFENDVHGIFYYSWSYVE 233

Query: 240 PPKYGVFYHHLDIIGKNGRI 259
           PPK   F    ++IG  G +
Sbjct: 234 PPKLPAF----EVIGTEGSV 249


>pir||A82502 oxidoreductase, Gfo/Idh/MocA family VCA0099 [imported] - Vibrio
           cholerae (group O1 strain N16961)
           >gi|9657485|gb|AAF96013.1| (AE004352) oxidoreductase,
           Gfo/Idh/MocA family [Vibrio cholerae]
           Length = 346
           
 Score = 87.8 bits (214), Expect = 2e-16
 Identities = 85/356 (23%), Positives = 163/356 (44%), Gaps = 39/356 (10%)

Query: 5   LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFL- 63
           LKVG+IG G      H P + +L ++  + A+    ++  ++   ++    F S    + 
Sbjct: 6   LKVGVIGYGYSAKTFHLPFIDTLESLT-LSAISSSQQQVVQEDWPQI--AYFDSAQRLIT 62

Query: 64  EQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVG 123
           E D+++V I  P   H  LA  AL+ GKHVIVEKP    +E+   +I+ A  Q L L V 
Sbjct: 63  ESDVDLVIITAPNNVHFPLAKLALEHGKHVIVEKPFVTQIEQGRTLIELARQQGLLLSVF 122

Query: 124 HVRRFDKRWIQIKDIIKSRNILPMQIRKIEV-QHLPFPADYWYWDESKSGGVIVDLGVHV 182
           H RR+D  ++ +K +I+   +  +++ +    ++ P     W     + GG++ DL  H+
Sbjct: 123 HNRRWDGDFLTVKKLIEQGQLGDVKVFESHFDRYRPVVRQRWREQAQEGGGILFDLAPHL 182

Query: 183 TDFLRWFFESEPIEVFAVGKAIRGEARVNK----THDHVVMFIKFEGGKTGIGEVSWSYP 238
            D        + + +F + +++  + R+ +    T D+  + + +      +    +S  
Sbjct: 183 LD--------QALVLFGLPQSLSADCRMMRPDATTLDYFDLQLYYPQHVVRLHANLYS-- 232

Query: 239 MPPKYGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPRFS-PMLSTFPQAFEAE-- 295
             P+  V Y  L  +GK  +    P +  +    + +   P++S  M   +   + AE  
Sbjct: 233 --PEPNVRYQVLGSLGKYVKYGLDPQEDRLKAGERPTH--PQWSQEMPEQYGILYHAEGN 288

Query: 296 ---------LRHFF----ECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKV 338
                     +H+F    E I++     V+A+ AL ++++ E A ES  KG+ + V
Sbjct: 289 ENVITELGGYQHYFTQVVEAIRNGASNPVSAESALQSIQLIELALESSAKGQRLAV 344


>sp|P49307|MOCA_RHIME RHIZOPINE CATABOLISM PROTEIN MOCA >gi|2120810|pir||S51572 mocA
           protein - Rhizobium meliloti >gi|468762|emb|CAA55269.1|
           (X78503) mocA [Sinorhizobium meliloti]
           Length = 317
           
 Score = 86.6 bits (211), Expect = 4e-16
 Identities = 81/339 (23%), Positives = 140/339 (40%), Gaps = 45/339 (13%)

Query: 4   KLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMD-IDEEAARKAGKELNAKVFTSLDEF 62
           + ++G++G G +  +  + A +S  ++ ++ AV D I       AG  +  K + +  + 
Sbjct: 3   RFRLGLVGAGRMGQVHVRAAAES--SLVEIAAVADPIAASRLNLAGNGI--KTYETAGDM 58

Query: 63  LEQ-DMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLF 121
           +E  +++ V I TP+ TH +   +    G  ++ EKP  +T EEA K    AE  ++ L 
Sbjct: 59  IEAGEVDGVLIATPSNTHVDTVADIAARGLPILCEKPCGVTAEEARKAADVAERYKVHLQ 118

Query: 122 VGHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPADYWYWDE--------SKSGG 173
           +G+ RRF     Q++D I++  +  + +              + WDE        +  GG
Sbjct: 119 IGYWRRFVPELKQLRDDIRAGLLGNLYL-----------VSCFQWDEAPPANSFRATGGG 167

Query: 174 VIVDLGVHVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEV 233
             +D+GVH  D +RW    EP               V    D V +      G +G+  V
Sbjct: 168 AFIDMGVHEFDQMRWLTGQEPTNFRVATSKTTFAGAVKGDPDAVQLLCDLSDGSSGL--V 225

Query: 234 SWSYPMPPKYGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPRFSPMLSTFPQAFE 293
           S     PP    +     + G +             G  ++ F  P      + F  A +
Sbjct: 226 SLGRRFPPGDACW---TQVFGTS-------------GFAEARFFWPPDGE--AVFLNALQ 267

Query: 294 AELRHFFECIKSSCEPVVTAQDALIALKIAEKAKESIKK 332
           A+L  F +  +       TA DA+ AL IAE A E + +
Sbjct: 268 AQLEDFVQAARGGAPRGATASDAVAALTIAEAATELLSR 306


>dbj|BAB05939.1| (AP001514) dehydrogenase [Bacillus halodurans]
           Length = 345
           
 Score = 86.2 bits (210), Expect = 5e-16
 Identities = 82/346 (23%), Positives = 151/346 (42%), Gaps = 16/346 (4%)

Query: 3   EKLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKV-FTSLDE 61
           + +KVG++G G +    H   L       ++ AV  + E   ++A +       +TS +E
Sbjct: 2   KSVKVGLVGLGRL-GQQHGDNLAFRIPRCELTAVCSVVEAEVKQARERWGVPYGYTSYEE 60

Query: 62  FL-EQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKL 120
            L  ++++ + I +P+  H E   + L+ G HV  EKP+ L + E  ++       + ++
Sbjct: 61  MLANEELDAIFIASPSGFHCEQIKKGLEKGFHVFCEKPLGLHLAEVREVENAVNRHKDQV 120

Query: 121 FV-GHVRRFDKRWIQIKDIIKSRNI-LPMQIRKIEVQHLPFPADYWYWDESK-SGGVIVD 177
           F+ G +RR+D  +   K+ I    I  P+ IR   +        +  + ++  SGG+ +D
Sbjct: 121 FMLGFMRRYDPSYQAAKEKINRGEIGEPVLIRCYGLDPASQIDGFLAFAKANDSGGLFLD 180

Query: 178 LGVHVTDFLRWFFESEPIEVFAVGKAI-RGEARVNKTHDHVVMFIKFEGGKTGIGEVSWS 236
           + +H  D  RW+  +E  EV+A+G +  R E       +     ++F+    G+      
Sbjct: 181 MSIHDFDLARWYLGAEASEVWAIGGSYSRPEFAELGDAETGAAMVRFDNQAIGL------ 234

Query: 237 YPMPPKYGVFYH-HLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPR--FSPMLSTFPQAFE 293
           +         YH   +IIG  G IR   +      VV +   +        +  F QA+ 
Sbjct: 235 FVAGRNCAHGYHIETEIIGTKGTIRIGSIPERNQAVVMNEHGVIHECVQGFIERFEQAYR 294

Query: 294 AELRHFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKVE 339
           AE   F  CI    +P VT +D + + K+    K+S      + V+
Sbjct: 295 AEAEEFIRCILEGRKPDVTVKDGVESTKLGYACKQSFTTKTLINVQ 340


>emb|CAC12307.1| (AL445066) glucose-fructose oxidoreductase related protein
           [Thermoplasma acidophilum]
           Length = 321
           
 Score = 86.2 bits (210), Expect = 5e-16
 Identities = 82/287 (28%), Positives = 122/287 (41%), Gaps = 39/287 (13%)

Query: 5   LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELN--------AKVF 56
           +KV IIG  N F   H  A   L          D+D E   +  + +          KV 
Sbjct: 1   MKVNIIGL-NGFGKRHIEAWSKL----------DVDIEITERKAEVVRDLLSRYDIVKVN 49

Query: 57  TSLDEFLEQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQ 116
           +SL+E    D  + +++ P   H ++ +++L  GKHV+VEKPIA  + +A +MI+ A   
Sbjct: 50  SSLEEAFNSDAEIFDLVLPHNLHHDVTVKSLAMGKHVMVEKPIATDISDAREMIRTAVQN 109

Query: 117 ELKLFVGHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPADYWYWDESKS---GG 173
             K  V     FD    + K+I+ S  I  +    I  Q      ++  W    S   GG
Sbjct: 110 RRKFMVADQYYFDPSVWKAKEIMDSGKIGSVHTIIIRDQR---KYNWHGWRSQASIMGGG 166

Query: 174 VIVDLGVHVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEV 233
            ++D G+H  D +      E I V +     R  A + +  D V    KF+ G  G+   
Sbjct: 167 PLIDGGIHFIDTM-LNLAGEYISVRS--NFYRSVASIEEP-DTVEAIFKFKDGSNGLFFY 222

Query: 234 SWSYPMPPKYGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPR 280
           SW YP PP    F    +IIG +G I       P      S+FE P+
Sbjct: 223 SWGYPYPPSLPSF----EIIGTDGSILEDLRSKP------SNFEAPK 259


>dbj|BAB05940.1| (AP001514) unknown conserved protein [Bacillus halodurans]
           Length = 345
           
 Score = 85.8 bits (209), Expect = 7e-16
 Identities = 81/342 (23%), Positives = 149/342 (42%), Gaps = 19/342 (5%)

Query: 5   LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFLE 64
           + +G+IG G I  L     + S     K V+ + +D     +  + +        + F  
Sbjct: 4   VNIGLIGAGRIGQLHASNIISSPYMELKAVSDVQLDHLKGTEIERSVEIMTTNPDELFSN 63

Query: 65  QDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVGH 124
           +D++ + I + T THA     A  AGKH+  EKPI+  V E +  +       +K  VG 
Sbjct: 64  RDIDAIFICSSTDTHAAFIKAAALAGKHIFCEKPISFHVTETKGALNIVNEAGVKFQVGF 123

Query: 125 VRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPADYWYWDESKSGGVIVDLGVHVTD 184
            RR+DK + ++++ +++  I    I ++  +    P   +     +SGG+ +D+ +H  D
Sbjct: 124 NRRYDKHFRRVQECVQAGAIGAPHIIRVSSRDPEAPPLSYV---ERSGGMFMDMTIHDFD 180

Query: 185 FLRWFFESEPIEVFAVGKAIRGEARVNKTH--DHVVMFIKFEGGKTGIGEVS--WSYPMP 240
            +R+   SE  EV +V  A   ++R+ +    D  ++ +  E G   + + S   +Y   
Sbjct: 181 MVRYLSGSEVTEV-SVKAANLVDSRIGEVGDVDTAIITLMLENGAIAVIDNSRQAAYGYD 239

Query: 241 PKYGVFYHHLDIIGKNGR---IRYTPMDTPVVGVVKSSFEMPRFSPMLSTFPQAFEAELR 297
            +  VF     +   N R   ++ +  DT  + + K  F        L  + QA++ E+ 
Sbjct: 240 QRVEVFGSLGSVSADNERKTNVQISTKDTVTLDLPKHFF--------LDRYEQAYKDEVA 291

Query: 298 HFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKVE 339
            F   I        T +D   A  +A  AK+S  +  PV V+
Sbjct: 292 EFATAILEDQPLRCTGEDGYKAELLALAAKQSWLENRPVAVK 333


>pir||S70672 dehydrogenase homolog - Bordetella pertussis
           >gi|992971|emb|CAA62245.1| (X90711) gene referred to as
           bplA in Mol. Microbiol. 19:37-52(1996) [Bordetella
           pertussis] >gi|3451515|emb|CAA07671.1| (AJ007747)
           putative oxidoreductase [Bordetella bronchiseptica]
           >gi|1589221|prf||2210367C bplA gene [Bordetella
           pertussis]
           Length = 350
           
 Score = 85.4 bits (208), Expect = 9e-16
 Identities = 86/356 (24%), Positives = 151/356 (42%), Gaps = 49/356 (13%)

Query: 4   KLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFL 63
           K++ G++GCG I +  H  A+      A++V + D + EA + A     A+ F+SL + L
Sbjct: 10  KIRFGLVGCGRI-SKNHIGAIAQHGDRAELVEICDTNPEALQAAEAATGARPFSSLSDML 68

Query: 64  EQ-DMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFV 122
            Q + + + + TP+  H   AIE  +AG+HV+ EKP+A   E+ ++M+K  +   ++LFV
Sbjct: 69  AQGNADALVLATPSGLHPWQAIEVAQAGRHVVSEKPMATRWEDGKRMVKACDEAGVRLFV 128

Query: 123 GHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPADY---------WYWDESKSGG 173
               R +     +K  I+      + +  + V     P +Y         W WD    GG
Sbjct: 129 VKQNRRNATLQLVKKAIEQGRFGRIYMVTVNV-FWTRPQEYYDAARWRGKWEWD----GG 183

Query: 174 VIVDLGVHVTDFLRWFFESEPIE-VFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTG-IG 231
             ++   H  D L W     P+E V+A    +   AR  +  D  V  +++  G  G I 
Sbjct: 184 AFMNQASHYVDLLDWLV--GPVESVYAYTATL---ARRIEAEDTGVAALRWRHGAMGSIN 238

Query: 232 EVSWSYPMPPKYGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPRFSPMLSTFPQA 291
               +YP   +  +      I+G+ G +R       V GV  +  +  +F+       + 
Sbjct: 239 VTMLTYPQNLEGSI-----TILGEKGTVR-------VGGVAVNRIDEWKFAEPHPDDDKI 286

Query: 292 FEAELR--------------HFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKG 333
            EA                 +   C++  CEP    ++ L +L +      S + G
Sbjct: 287 REANYETTSVYGFGHPLYYDNVINCLRGDCEPETDGREGLQSLALLTAIYRSARDG 342


>emb|CAB02496.1| (Z80356) glucose-fructose oxidoreductase [Zymomonas mobilis]
           Length = 433
           
 Score = 84.7 bits (206), Expect = 1e-15
 Identities = 65/277 (23%), Positives = 122/277 (43%), Gaps = 7/277 (2%)

Query: 67  MNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVGHVR 126
           ++ V I+ P   HAE AI A KAGKHV+ EKP+A +V + ++MI  A+    KL +G+  
Sbjct: 151 IDAVYIILPNSLHAEFAIRAFKAGKHVMCEKPMATSVADCQRMIDAAKAANKKLMIGYRC 210

Query: 127 RFDKRWIQIKDIIKSRNILPMQI---RKIEVQHLPFPADYW-YWDESKSGGVIVDLGVHV 182
            +D        +I+   +  + +      +V     PA  W    E   GG ++D+G++ 
Sbjct: 211 HYDPMNRAAVKLIRENQLGKLGMVTTDNSDVMDQNDPAQQWRLRRELAGGGSLMDIGIYG 270

Query: 183 TDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWSYPMPPK 242
            +  R+    EPIEV A   +   + R  +  D ++  ++F  G    G  S+S     +
Sbjct: 271 LNGTRYLLGEEPIEVRAYTYSDPNDERFVEVEDRIIWQMRFRSGALSHGASSYSTTTTSR 330

Query: 243 YGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPRFSPMLSTFPQAFEAELRHFFEC 302
           + V      ++       Y  + +       +   MP+F   +      F A+L H  E 
Sbjct: 331 FSVQGDKAVLLMDPATGYYQNLISVQTPGHANQSMMPQF---IMPANNQFSAQLDHLAEA 387

Query: 303 IKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKVE 339
           + ++       ++ +  +++ +   E+ + G PV  +
Sbjct: 388 VINNKPVRSPGEEGMQDVRLIQAIYEAARTGRPVNTD 424


>pdb|1OFG|A Chain A, Glucose-Fructose Oxidoreductase >gi|2098324|pdb|1OFG|B
           Chain B, Glucose-Fructose Oxidoreductase
           >gi|2098325|pdb|1OFG|C Chain C, Glucose-Fructose
           Oxidoreductase >gi|2098326|pdb|1OFG|D Chain D,
           Glucose-Fructose Oxidoreductase >gi|2098327|pdb|1OFG|E
           Chain E, Glucose-Fructose Oxidoreductase
           >gi|2098328|pdb|1OFG|F Chain F, Glucose-Fructose
           Oxidoreductase
           Length = 381
           
 Score = 84.7 bits (206), Expect = 1e-15
 Identities = 65/277 (23%), Positives = 122/277 (43%), Gaps = 7/277 (2%)

Query: 67  MNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVGHVR 126
           ++ V I+ P   HAE AI A KAGKHV+ EKP+A +V + ++MI  A+    KL +G+  
Sbjct: 99  IDAVYIILPNSLHAEFAIRAFKAGKHVMCEKPMATSVADCQRMIDAAKAANKKLMIGYRC 158

Query: 127 RFDKRWIQIKDIIKSRNILPMQI---RKIEVQHLPFPADYW-YWDESKSGGVIVDLGVHV 182
            +D        +I+   +  + +      +V     PA  W    E   GG ++D+G++ 
Sbjct: 159 HYDPMNRAAVKLIRENQLGKLGMVTTDNSDVMDQNDPAQQWRLRRELAGGGSLMDIGIYG 218

Query: 183 TDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWSYPMPPK 242
            +  R+    EPIEV A   +   + R  +  D ++  ++F  G    G  S+S     +
Sbjct: 219 LNGTRYLLGEEPIEVRAYTYSDPNDERFVEVEDRIIWQMRFRSGALSHGASSYSTTTTSR 278

Query: 243 YGVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPRFSPMLSTFPQAFEAELRHFFEC 302
           + V      ++       Y  + +       +   MP+F   +      F A+L H  E 
Sbjct: 279 FSVQGDKAVLLMDPATGYYQNLISVQTPGHANQSMMPQF---IMPANNQFSAQLDHLAEA 335

Query: 303 IKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKVE 339
           + ++       ++ +  +++ +   E+ + G PV  +
Sbjct: 336 VINNKPVRSPGEEGMQDVRLIQAIYEAARTGRPVNTD 372


>gb|AAD45293.1|AF156256_1 (AF156256) putative dehydrogenase [Vibrio anguillarum]
           Length = 318
           
 Score = 84.3 bits (205), Expect = 2e-15
 Identities = 73/268 (27%), Positives = 120/268 (44%), Gaps = 27/268 (10%)

Query: 4   KLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFL 63
           K+++ ++GCG I +  H  +++ L +  ++VAV D + E       +     + S+D+ L
Sbjct: 6   KIRIAVVGCGRI-SKNHFGSIEQLDSEYELVAVCDNNPEVLELHSNKYGVPGYHSIDDLL 64

Query: 64  -EQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFV 122
             Q +++V + TP+  HA   I+A KAG HVI EKP+A   E+   M+K  ++  ++LFV
Sbjct: 65  ASQTLDIVTLCTPSGIHAPQTIKAAKAGVHVITEKPMATKWEDGLAMVKACDDAGVRLFV 124

Query: 123 GHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPF----PADY-----WYWDESKSGG 173
               R +     +K     R +   +  KI + HL      P +Y     W       GG
Sbjct: 125 VKQNRRNSTLQLLK-----RAVTEKRFGKIHMVHLNVFWTRPQEYYDRAAWSGTWHMDGG 179

Query: 174 VIVDLGVHVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEV 233
             ++   H  D L W     PIE      A+    R  +  D  V+ IK+  G  G   V
Sbjct: 180 AFMNQATHYVDLLHWLV--GPIETI---HAMTSTHRDIEVEDTGVVNIKWRNGALGSMAV 234

Query: 234 SW-SYPMPPKYGVFYHHLDIIGKNGRIR 260
           +  +YP           + I G+ G +R
Sbjct: 235 TMCTYP-----NNLEGSITIFGEKGTVR 257


>sp|O32223|YVAA_BACSU HYPOTHETICAL OXIDOREDUCTASE IN FHUD-OPUBD INTERGENIC REGION
           >gi|7449498|pir||G70026 conserved hypothetical protein
           yvaA - Bacillus subtilis >gi|2635866|emb|CAB15358.1|
           (Z99121) similar to hypothetical proteins [Bacillus
           subtilis]
           Length = 358
           
 Score = 83.1 bits (202), Expect = 4e-15
 Identities = 85/364 (23%), Positives = 151/364 (41%), Gaps = 45/364 (12%)

Query: 3   EKLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEF 62
           + +KVGI+G G   ++ H P L  L        +    EE  R      +A+V   L+E 
Sbjct: 12  DTIKVGILGYGLSGSVFHGPLLDVLDEYQISKIMTSRTEEVKRDFP---DAEVVHELEEI 68

Query: 63  LEQD-MNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLF 121
                + +V + TP+  H E  +  ++AGKHV++EKP+  T EE E + + A+ + + L 
Sbjct: 69  TNDPAIELVIVTTPSGLHYEHTMACIQAGKHVVMEKPMTATAEEGETLKRAADEKGVLLS 128

Query: 122 VGHVRRFDKRWIQIKDIIKSRNILPMQIRKIEV-QHLPFPADYWYWDESKSGGVIVDLGV 180
           V H RR+D  ++ IK +I   ++  +   ++   ++ P     W   E  + G + DLG 
Sbjct: 129 VYHNRRWDNDFLTIKKLISEGSLEDINTYQVSYNRYRPEVQARWREKEGTATGTLYDLGS 188

Query: 181 HVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWSYPMP 240
           H+ D        + + +F + KA+       + +   V +         +  + +   + 
Sbjct: 189 HIID--------QTLHLFGMPKAVTANVMAQRENAETVDYFHLTLDYGKLQAILYGGSIV 240

Query: 241 PKYGVFY--HHLD-------IIGKNGRIR--YTPMD--------------TPVVGVVKSS 275
           P  G  Y  H  D       I G+   +R    P D              T + G  K +
Sbjct: 241 PANGPRYQIHGKDSSFIKYGIDGQEDALRAGRKPEDDSWGADVPEFYGKLTTIRGSDKKT 300

Query: 276 FEMPRFSPMLSTFPQAFEAELRHFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEP 335
             +P  +    T+        R   E I+      VTA++ +  ++I E A ES K+   
Sbjct: 301 ETIPSVNGSYLTY-------YRKIAESIREGAALPVTAEEGINVIRIIEAAMESSKEKRT 353

Query: 336 VKVE 339
           + +E
Sbjct: 354 IMLE 357


>sp|P74041|Y816_SYNY3 HYPOTHETICAL 41.5 KD PROTEIN SLL0816 >gi|7469938|pir||S75555
           hypothetical protein sll0816 - Synechocystis sp. (strain
           PCC 6803) >gi|1653200|dbj|BAA18116.1| (D90911)
           hypothetical protein [Synechocystis sp.]
           Length = 371
           
 Score = 81.1 bits (197), Expect = 2e-14
 Identities = 60/194 (30%), Positives = 98/194 (49%), Gaps = 12/194 (6%)

Query: 5   LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELN-AKVFTSLDEFL 63
           L V +IG G      H PAL+  +   + +A+   D   A++  K  + A  + +L+E L
Sbjct: 7   LTVAVIGTG-FGQAVHIPALQYHQQ-TQAIAIYHRDLAKAQEVAKSNDLAYSYNNLEELL 64

Query: 64  EQ-DMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFV 122
              ++  V I +P + H E+A +A+ AGKHV++EKP+ L VEE  ++   A  +E+++  
Sbjct: 65  ANPEVQAVTIASPPFLHYEMAKQAILAGKHVLLEKPMTLRVEETIELYHLARQREVQVIP 124

Query: 123 GHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHL------PFPADYWYWDESKSGGVIV 176
               RF   W  + +++  + IL  Q++ I+V  L      P  A  WY    K GG + 
Sbjct: 125 DFEFRFVPAWQYVAELL-GQGILG-QLKLIKVDWLVGSRANPNRAWNWYAQREKGGGALG 182

Query: 177 DLGVHVTDFLRWFF 190
            L  H  D+L W F
Sbjct: 183 ALASHTFDYLHWLF 196


>pir||B75475 glucose-fructose oxidoreductase - Deinococcus radiodurans  (strain
           R1) >gi|6458511|gb|AAF10376.1|AE001934_7 (AE001934)
           glucose-fructose oxidoreductase [Deinococcus
           radiodurans]
           Length = 398
           
 Score = 80.8 bits (196), Expect = 2e-14
 Identities = 78/346 (22%), Positives = 153/346 (43%), Gaps = 20/346 (5%)

Query: 3   EKLKVG--IIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGK--ELNAKVFTS 58
           E+ +VG  I+G G +      PA ++ +  A + A++  +E+      +  +L      S
Sbjct: 41  EQKRVGFAIVGIGKLSAEELIPAARTSQH-AYIAALVTSEEDKGEAFARAFDLTPDDVYS 99

Query: 59  LDEFLE----QDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAE 114
            D+F +     D+  V I+ P   H E    A K GKHV+ EKP+++  ++A+ M+    
Sbjct: 100 YDDFEKLAGRDDVEAVYIVLPNSLHREYVERAAKMGKHVLCEKPLSVNEQDAQAMVDACR 159

Query: 115 NQELKLFVGHVRRFDKRWIQIKDIIKSRNILPMQ-IRKIEVQHLPFPADYWYWDESKSGG 173
              + L   +  ++       +D ++   +  ++ +  I VQ    P+ +    +   GG
Sbjct: 160 AANVLLMTAYRCQYTPEHWAARDAVQGGKLGKVKLLDSIHVQSEDDPSVWRLKLDLAGGG 219

Query: 174 VIVDLGVHVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEV 233
            + D+G++  + +R+    EP  VFA      G+ R  +  + V   + F GG   I  V
Sbjct: 220 PLPDVGLYSVNIIRFVLGQEPEWVFAALHQPEGDPRFGEVEESVSAMLGFPGGV--IANV 277

Query: 234 SWSYPMPPKYGVFYHHLDIIGKNGRIRYTPMDTPVVGV-VKSSFEMPRFSPMLSTFPQAF 292
             SY       +    L ++G+ G +   P   P  G+ ++ + +   FSP    + Q F
Sbjct: 278 LTSYG-----ALKTTTLRVMGEEGSLLMDPA-FPYDGLGLEITTDDGTFSPSFPEYDQ-F 330

Query: 293 EAELRHFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKV 338
             E  HF +C++    P    ++ +   ++ +   ES + G+ V++
Sbjct: 331 SREFDHFAQCVRGGQTPWTPGEEGVADHRVMDAIYESARTGKRVEL 376


>gb|AAD50452.1|AF170704_2 (AF170704) SpcB [Streptomyces spectabilis]
           Length = 374
           
 Score = 80.0 bits (194), Expect = 4e-14
 Identities = 42/142 (29%), Positives = 79/142 (55%), Gaps = 4/142 (2%)

Query: 3   EKLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKEL---NAKVFTSL 59
           E+++VG+IGCG +  + H P L+SL    ++ A+ D+        G+     + + FT  
Sbjct: 4   ERVRVGVIGCGTVAQIMHLPYLQSLSDQFEITALSDLSPGLLDALGERYGVPHGRRFTDY 63

Query: 60  DEFLEQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELK 119
              L+ D++ V +L+   +HA   + A +AGKHV+VEKP+  T+ EA+ +        ++
Sbjct: 64  RALLDTDVDAVLVLSGG-SHAPQVLAAAEAGKHVLVEKPLCFTLREADAIEAAVARSGVR 122

Query: 120 LFVGHVRRFDKRWIQIKDIIKS 141
           L V +++RFD  ++  K ++ +
Sbjct: 123 LMVAYMKRFDPGFLYGKQLVSA 144


>sp|P49305|YMO1_RHIME HYPOTHETICAL 36.4 KD PROTEIN IN MOCC-MOCA INTERGENIC REGION
           (ORF334) >gi|1073149|pir||S51570 hypothetical protein
           334 - Rhizobium meliloti >gi|468760|emb|CAA55267.1|
           (X78503) ORF334 [Sinorhizobium meliloti]
           Length = 334
           
 Score = 79.6 bits (193), Expect = 5e-14
 Identities = 62/198 (31%), Positives = 95/198 (47%), Gaps = 3/198 (1%)

Query: 5   LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELN-AKVFTSLDEFL 63
           ++ GIIG   I      P++ S   + +VVA+   D + AR A       + + S DE L
Sbjct: 4   VRFGIIGTAAIAVEKVIPSMLSAEGL-EVVAIASRDLDRARAAATRFGIGRSYGSYDEIL 62

Query: 64  -EQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFV 122
            + ++  V I  P + H   AI A +AGKHV+ EKP+AL VEE  ++I   +    ++  
Sbjct: 63  ADPEIEAVYIPLPNHLHVHWAIRAAEAGKHVLCEKPLALDVEELSRLIDCRDRTGRRIQE 122

Query: 123 GHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPADYWYWDESKSGGVIVDLGVHV 182
             + R   +W +I DI+ S  I  ++  +     +         D S  GG + DLGV+ 
Sbjct: 123 AVMIRAHPQWDEIFDIVASGEIGEVRAIQGVFTEVNLDPKSIVNDASIGGGALYDLGVYP 182

Query: 183 TDFLRWFFESEPIEVFAV 200
               R  F +EP  VFAV
Sbjct: 183 IAAARMVFAAEPERVFAV 200


>gb|AAF63338.1|AF244574_1 (AF244574) myo-inositol-2-dehydrogenase [Streptomyces spectabilis]
           Length = 374
           
 Score = 79.2 bits (192), Expect = 6e-14
 Identities = 42/142 (29%), Positives = 78/142 (54%), Gaps = 4/142 (2%)

Query: 3   EKLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNA---KVFTSL 59
           E+++VG+IGCG +  + H P L+SL    ++ A+ D+        G+       + FT  
Sbjct: 4   ERVRVGVIGCGTVAQIMHLPYLQSLPDQFEITALSDLSPGLLDALGERYGVPPGRRFTDY 63

Query: 60  DEFLEQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELK 119
              L+ D + V +L+   +HA   + A++AGKHV+VEKP+  T+ EA+ +        ++
Sbjct: 64  RALLDTDADAVLVLSGG-SHAPQVLAAVEAGKHVLVEKPLCFTLREADAIEAAVARSGVR 122

Query: 120 LFVGHVRRFDKRWIQIKDIIKS 141
           L V +++RFD  ++  K ++ +
Sbjct: 123 LMVAYMKRFDPGFLYGKQLVSA 144


>pir||T44834 hypothetical protein weeE [imported] - Acinetobacter lwoffii
           >gi|6009995|emb|CAB57202.1| (AJ243431) unknown
           [Acinetobacter lwoffii]
           Length = 712
           
 Score = 78.8 bits (191), Expect = 8e-14
 Identities = 74/236 (31%), Positives = 103/236 (43%), Gaps = 25/236 (10%)

Query: 7   VGIIGCGNIFNLAHKPALKS----LRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEF 62
           VG IG GN  +    PA K     L TI     +  +      K G    A+  T LD  
Sbjct: 393 VGFIGAGNYASRVLIPAFKKASSQLHTIVTSGGINGVIH--GEKTGF---AEASTDLDGL 447

Query: 63  LE-QDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKM-----IKEAENQ 116
           L  +D+N V I T   +HA      L AGK+V VEKP+ALTVEE EK+          NQ
Sbjct: 448 LNNKDINTVAIATRHNSHAYFVERVLSAGKNVFVEKPLALTVEEIEKIETVYNQNIQNNQ 507

Query: 117 ELKLFVGHVRRFDKRWIQIK---DIIKSRNILPMQIRKIEVQHLPFPADYWYWDESKSGG 173
             ++ VG  RRF  +  ++K   D +K      M +    +     PAD+W  D +  GG
Sbjct: 508 YARVMVGFNRRFSPQVQKMKTLLDTVKEPKSFIMTMNAGAI-----PADHWTQDNAVGGG 562

Query: 174 VIVDLGVHVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTG 229
            I+    H  D +R+   S+ + V A  + +     V    D   + + FE G  G
Sbjct: 563 RIIGEACHFIDLMRFLAGSKIVSVQA--RRMGETDAVQVLEDKASITLGFEDGSFG 616


>pir||T38428 hypothetical oxidoreductase - fission yeast  (Schizosaccharomyces
           pombe) >gi|2398818|emb|CAB16194.1| (Z99126) hypothetical
           oxidoreductase [Schizosaccharomyces pombe]
           Length = 369
           
 Score = 78.0 bits (189), Expect = 1e-13
 Identities = 58/186 (31%), Positives = 92/186 (49%), Gaps = 8/186 (4%)

Query: 5   LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMD----IDEEAARKAGKELNAKVFTSLD 60
           +K  ++G G    + H P LK+L    +V A  +      E  AR A    N KV+T LD
Sbjct: 4   IKTAVLGTGMSAFIFHYPFLKALPNHFEVYAAWERRATSTESKARAAFP--NVKVYTKLD 61

Query: 61  EFL-EQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELK 119
           E L + ++ +V I  P   H E+  +AL AGKHV+ EKP   T  EA+++   A+++ L 
Sbjct: 62  ELLADSNIELVVISLPPNVHYEVVSQALNAGKHVLCEKPFTPTYGEAKELFDLAKSKNLM 121

Query: 120 LFVGHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLP-FPADYWYWDESKSGGVIVDL 178
           L V   RRFD  ++  K+ I++  +  +   +  +     F    W    +   G++ DL
Sbjct: 122 LTVYQNRRFDGDFLTAKECIENGRLGEVVQFESHIDRFRLFRKGNWKDVPNPGCGLVYDL 181

Query: 179 GVHVTD 184
           G H+ D
Sbjct: 182 GSHLID 187


>sp|Q05184|PHT4_PSEPU PUTATIVE 4,5,-DIHYDROXYPHTHALATE DEHYDROGENASE (DHP DEHYDROGENASE)
           >gi|295711|dbj|BAA02512.1| (D13229) PHT4 [Pseudomonas
           putida]
           Length = 410
           
 Score = 77.6 bits (188), Expect = 2e-13
 Identities = 51/199 (25%), Positives = 98/199 (48%), Gaps = 5/199 (2%)

Query: 4   KLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFL 63
           +L++G++G G  F L     L   R   ++V   D  E+A R+  ++ +A  + ++++  
Sbjct: 11  RLRLGVVGLGRAFTLMLPTFLADRRV--QLVGACDPREQARRQFERDFDAPAYETIEDLA 68

Query: 64  -EQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFV 122
            + +++ + I +P   HAE    A    KHV+VEKP+AL+++E ++MI +     +KL V
Sbjct: 69  ADSNVDALYIASPHQFHAEHTRIAAANRKHVLVEKPMALSLDECDRMIADCAEAGVKLIV 128

Query: 123 GHVRRFDKRWIQIKDIIKSRNILPMQIRKI--EVQHLPFPADYWYWDESKSGGVIVDLGV 180
           GH   FD  +++ +++I S     +++ +      +L  P        ++ GG +     
Sbjct: 129 GHCHSFDTPYLRTRELIGSGEFGAVKMIQALNYTDYLQRPRRPEELSTAEGGGAVFSQAA 188

Query: 181 HVTDFLRWFFESEPIEVFA 199
           H  D +R    S    V A
Sbjct: 189 HQVDVVRLLAGSRATRVRA 207


>pir||G72391 conserved hypothetical protein - Thermotoga maritima (strain MSB8)
           >gi|4980813|gb|AAD35400.1|AE001713_4 (AE001713)
           conserved hypothetical protein [Thermotoga maritima]
           Length = 328
           
 Score = 77.3 bits (187), Expect = 2e-13
 Identities = 66/263 (25%), Positives = 118/263 (44%), Gaps = 18/263 (6%)

Query: 4   KLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKEL-NAKVFTSLDEF 62
           K+++GI+GCG      H PALK+L  + ++ AV       A +  K + N  VF S +E 
Sbjct: 6   KIRLGIVGCGIAARELHLPALKNLSHLFEITAVTSRTRSHAEEFAKMVGNPAVFDSYEEL 65

Query: 63  LEQDM-NVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLF 121
           LE  + + V++  P   +     +AL+ G HVI EKPI+  VE  +K+++ +E  E  ++
Sbjct: 66  LESGLVDAVDLTLPVELNLPFIEKALRKGVHVICEKPISTDVETGKKVVELSEKSEKTVY 125

Query: 122 VGHVRRFDKRWIQIKDIIKSRNI-----LPMQIRKIEVQHLPFPADYWYWDESKSGGVIV 176
           +    R    + + K++++S  I     +  QI     ++  +    W       GG + 
Sbjct: 126 IAENFRHVPAFWKAKELVESGAIGDPVFMNWQIWVGMDENNKYVHTDWRKKPKHVGGFLS 185

Query: 177 DLGVHVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWS 236
           D GVH    +R        E+  +    +  + +    D +    +FE G  G   +S+S
Sbjct: 186 DGGVHHAAAMRLILG----EIEWISAVAKDLSPLLGGMDFLSSIFEFENGTVGNYTISYS 241

Query: 237 YPMPPKYGVFYHHLDIIGKNGRI 259
                ++       +I G  G+I
Sbjct: 242 LKGNERF-------EITGTKGKI 257


>pir||A83004 conserved hypothetical protein PA5149 [imported] - Pseudomonas
           aeruginosa (strain PAO1)
           >gi|9951449|gb|AAG08534.1|AE004927_12 (AE004927)
           conserved hypothetical protein [Pseudomonas aeruginosa]
           Length = 360
           
 Score = 77.3 bits (187), Expect = 2e-13
 Identities = 57/210 (27%), Positives = 102/210 (48%), Gaps = 18/210 (8%)

Query: 5   LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFLE 64
           ++  +IG G      H P ++++  +     V     +  R       A+V    DE +E
Sbjct: 11  IRTALIGYGFAGKTFHAPLIRAVPALCLEHVV---SRDPGRVHADLPEARVSADPDEAIE 67

Query: 65  Q-DMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEK---MIKEAENQELKL 120
             D+++V I +P  THA LA  AL+AGKHV+V+KP  +T+ EA +   + +E   Q L +
Sbjct: 68  AADIDLVVIASPNATHASLAERALRAGKHVVVDKPFTVTLAEARRLADLARERPGQVLSV 127

Query: 121 FVGHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHL-PFPADYWYWDESKSGGVIVDLG 179
           F    RRFD  ++ ++  +++ +I P++  +  ++   P   D W   +    G+  DLG
Sbjct: 128 FQN--RRFDSDFLAVEAALQAGSIGPVRYFESAIERFRPQVRDRWREHDLPGSGLWFDLG 185

Query: 180 VHVTDFLRWFFESEPIEVFAVGKAIRGEAR 209
            H+ D        + + +F V + + G  R
Sbjct: 186 PHLLD--------QALCLFGVPQRVHGHLR 207


>gb|AAF13758.1|AF117351_15 (AF117351) MviM [Zymomonas mobilis]
           Length = 358
           
 Score = 76.9 bits (186), Expect = 3e-13
 Identities = 58/187 (31%), Positives = 94/187 (50%), Gaps = 11/187 (5%)

Query: 3   EKLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEF 62
           E +KVG+IG G +    H P + ++  + ++ A++    E  R+   ++   V+  +D  
Sbjct: 6   EIIKVGLIGYGYVGKTFHAPFIDAVEGL-ELSAIVSSHPETVREDWPDM--AVYPDIDIM 62

Query: 63  LEQ-DMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLF 121
           L   ++++V I TP  TH  LA  AL AG+HV+V+KP  LT E+A  +   AE ++  L 
Sbjct: 63  LSNSNVDLVVIATPNDTHKPLAERALLAGRHVVVDKPFTLTTEDARYLAALAEKEKKLLS 122

Query: 122 VGHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHL----PFPADYWYWDESKSGGVIVD 177
           V   RR+D  ++ +K  I+    L   I + E  HL    P     W  +    GG+  D
Sbjct: 123 VFQNRRWDSDFLGVKQAIEKD--LLGDIAQFE-SHLDRFRPVVRQRWREEAVAGGGLWYD 179

Query: 178 LGVHVTD 184
           L  H+ D
Sbjct: 180 LAPHMVD 186


>pir||T39296 Oxidoreductase - fission yeast (Schizosaccharomyces pombe)
           >gi|2956751|emb|CAA17915.1| (AL022105) Oxidoreductase
           [Schizosaccharomyces pombe]
           Length = 368
           
 Score = 76.5 bits (185), Expect = 4e-13
 Identities = 55/189 (29%), Positives = 99/189 (52%), Gaps = 13/189 (6%)

Query: 5   LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMD----IDEEAARKAGKELNAKVFTSLD 60
           +K  ++G G    + H P L++L +  ++ A ++    + +  AR A    N  V+T+LD
Sbjct: 4   IKTAVLGTGVSAFVFHFPFLEALPSKFEIYACLERRATVTQSKARSAYP--NILVYTNLD 61

Query: 61  EFL-EQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELK 119
           E L + ++ +V +  P   H+E+  +AL AGKHV+ EKP   T EEA+++ + AE++ L 
Sbjct: 62  ELLADVNIELVVVSLPPNVHSEIVKKALNAGKHVVCEKPFTPTYEEAKELYELAESKSLL 121

Query: 120 LFVGHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQ----HLPFPADYWYWDESKSGGVI 175
           L +   RR+D  ++  K II+S  +   Q+ + E       L   +  W  +     G++
Sbjct: 122 LAIYQNRRWDGDFLTAKKIIESGRL--GQVVEFESHFDRYRLGRKSGSWKDEPRPGNGMV 179

Query: 176 VDLGVHVTD 184
             +G H+ D
Sbjct: 180 YGIGSHLID 188


>gb|AAD45545.1|U70376_10 (U70376) SpcB [Streptomyces flavopersicus]
           Length = 392
           
 Score = 76.5 bits (185), Expect = 4e-13
 Identities = 37/130 (28%), Positives = 72/130 (54%), Gaps = 4/130 (3%)

Query: 3   EKLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKV---FTSL 59
           +++++G+IGCG +  + H P L+SL    ++ A+ D+        G+         F   
Sbjct: 21  QRIRIGVIGCGTVAQIMHLPYLRSLPAQFEIFALSDLSPGLLDLLGERYGVPATRRFLDY 80

Query: 60  DEFLEQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELK 119
              LE +++ V +L+   +HA   + A +AGKH++VEKP+  T+ EA+++       +++
Sbjct: 81  RGLLESEVDAVLVLSAG-SHAPQVLAAAEAGKHILVEKPLCFTLREADEIAAAVSRSQVR 139

Query: 120 LFVGHVRRFD 129
           L V +++RFD
Sbjct: 140 LMVAYMKRFD 149


>emb|CAB65577.1| (AL136058) putative oxidoreductase. [Streptomyces coelicolor A3(2)]
           Length = 360
           
 Score = 75.3 bits (182), Expect = 1e-12
 Identities = 52/187 (27%), Positives = 94/187 (49%), Gaps = 9/187 (4%)

Query: 5   LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFLE 64
           L+VG++G G   ++ H P + +   +A    V    E   +   +  + +   + DE  +
Sbjct: 11  LRVGLVGYGLAGSVFHAPLIAATEGLALDTVVTSNPERQQQARAEFPDVRTVATPDELFD 70

Query: 65  Q--DMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFV 122
           +  ++++V + +P  TH  LA  AL+AG  V+V+KP+A T  EA  +   AE + L L V
Sbjct: 71  RAAELDLVVVASPNKTHVPLATRALEAGLPVVVDKPVAGTAAEARALAALAEERGLLLSV 130

Query: 123 GHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQH---LPFPADYW--YWDESKSGGVIVD 177
              RR+D  ++ ++ ++    +   ++ + E +     P P   W    D S+ GG++ D
Sbjct: 131 FQNRRWDNDFLTLRQLLAEDAL--GEVWRFESRFERWRPKPKGGWRESGDPSEIGGLLYD 188

Query: 178 LGVHVTD 184
           LG HV D
Sbjct: 189 LGSHVVD 195


>gb|AAG09709.1|AF218837_4 (AF218837) unknown [Pasteurella multocida]
           Length = 367
           
 Score = 75.3 bits (182), Expect = 1e-12
 Identities = 71/265 (26%), Positives = 114/265 (42%), Gaps = 25/265 (9%)

Query: 5   LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFLE 64
           +K G++G G  +  A      +    AKV  V D   E      KEL     TSL + + 
Sbjct: 2   MKYGVVGVG--YFGADLARFMNENENAKVTMVYD--PENGETIAKELQCIAATSLKQLVS 57

Query: 65  Q-DMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVG 123
             +++ V + TP Y H E  IEA K GKHV  EKPIAL  ++ ++M++  E   +    G
Sbjct: 58  SPEVDCVIVATPNYLHKEPVIEAAKHGKHVFCEKPIALNYQDCDEMVRTCEENGVIFMAG 117

Query: 124 HVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHL-------PFPADYWYWDESKSGGVIV 176
           HV  F       K++IK        I K+   H           +  W    +KSGG + 
Sbjct: 118 HVMNFFNGVHHAKELIKQG-----VIGKVLYCHSARNGWEDEQSSISWKKIRAKSGGHLY 172

Query: 177 DLGVHVTDFLRWFFESEPIEV-FAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSW 235
              +H  D +++     P  V    G       +     D + + ++FEGG+  + E   
Sbjct: 173 H-HIHELDCIQFIMGGMPKTVTMTAGNVAHQSEKFGDEDDMLFLNLEFEGGRFAVLEWGS 231

Query: 236 SYPMPPKYGVFYHHLDIIGKNGRIR 260
           ++    ++G   H++ I G+ G I+
Sbjct: 232 AF----RWG--EHYVLIQGEKGAIK 250


>emb|CAC11395.1| (AL445063) glucose-fructose oxidoreductase related protein
           [Thermoplasma acidophilum]
           Length = 322
           
 Score = 74.5 bits (180), Expect = 2e-12
 Identities = 71/266 (26%), Positives = 119/266 (44%), Gaps = 34/266 (12%)

Query: 5   LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNA-KVFTSLDEFL 63
           + + ++GC        K  L+    +   V++++ D   A++  +     KV+ + ++ L
Sbjct: 1   MDIVLVGCKGF----GKEHLRIYSKLGYDVSIVERDSNEAKRCSELFRVYKVYDNYEDAL 56

Query: 64  EQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVG 123
               N+V+++ P   H E+   ALK+ KH++VEKPI   ++    +I++AE  +LKL V 
Sbjct: 57  RSGSNIVDLVVPDGLHYEMGSLALKSKKHLLVEKPITPDIDSGISLIQQAEESKLKLMVA 116

Query: 124 HVRRFDKRWIQIKDIIKSRNILPMQIRK---IEVQHLPF-PADYWYWDESKSG-GVIVDL 178
               FD     + + I  R I   +I K   + V+H  F     W  ++S  G G+++D 
Sbjct: 117 EQFYFDP---SVNEAI--RRINNGEIGKPHTVIVRHQSFRELKGWRNEKSMMGRGILIDE 171

Query: 179 GVHVTDFLRWFFESEPIEVFAVGKAIRGEARVNKT-----HDHVVMFIKFEGGKTGIGEV 233
           G H  D L  F           G+     + V++T      D       FE G  G+   
Sbjct: 172 GTHYIDTLLNF----------GGRYRSLRSFVHRTWDFLGEDTAEAVFNFENGMHGLFFY 221

Query: 234 SWSYPMPPKYGVFYHHLDIIGKNGRI 259
           SW+YP  P    F    +IIG  G I
Sbjct: 222 SWNYPEYPLLPEF----EIIGDAGSI 243


>sp|Q07982|GFO_ZYMMO GLUCOSE--FRUCTOSE OXIDOREDUCTASE PRECURSOR (GFOR)
           >gi|95542|pir||A42289 glucose-fructose oxidoreductase
           (EC 1.1.-.-) precursor - Zymomonas mobilis
           >gi|155588|gb|AAA27690.1| (M97379) glucose-fructose
           oxidoreductase [Zymomonas mobilis]
           Length = 439
           
 Score = 73.7 bits (178), Expect = 3e-12
 Identities = 59/276 (21%), Positives = 119/276 (42%), Gaps = 6/276 (2%)

Query: 67  MNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVGHVR 126
           ++ V I+ P   HAE AI + KAGKHV+ EKP+A +V + ++MI  A+    KL +G+  
Sbjct: 150 IDAVYIILPNSLHAEFAIRSFKAGKHVMCEKPMATSVADCQRMIDAAKAANKKLMIGYRC 209

Query: 127 RFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPADY---WYWDESKSGGVIVDLGVHVT 183
            +D        +I+   +  + +   +   +    D         +  GG ++D+G++  
Sbjct: 210 HYDPMNRAAVKLIRENQLGKLGMVTTDNSDVMDQNDLHSSGVCVVNSGGGSLMDIGIYGL 269

Query: 184 DFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWSYPMPPKY 243
           +  R+    EPIEV A   +   + R  +  D ++  ++F  G    G  S+S     ++
Sbjct: 270 NGTRYLLGEEPIEVRAYTYSDPNDERFVEVEDRIIWQMRFRSGALSHGASSYSTTTTSRF 329

Query: 244 GVFYHHLDIIGKNGRIRYTPMDTPVVGVVKSSFEMPRFSPMLSTFPQAFEAELRHFFECI 303
            V      ++       Y  + +       +   MP+F   +      F A+L H  E +
Sbjct: 330 SVQGDKAVLLMDPATGYYQNLISVQTPGHANQSMMPQF---IMPANNQFSAQLDHLAEAV 386

Query: 304 KSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKVE 339
            ++       ++ +  +++ +   E+ + G  V  +
Sbjct: 387 INNKPVRSPGEEGMQDVRLIQAIYEAARTGRAVNTD 422


>dbj|BAB07562.1| (AP001520) oxidoreductase [Bacillus halodurans]
           Length = 334
           
 Score = 73.7 bits (178), Expect = 3e-12
 Identities = 70/263 (26%), Positives = 116/263 (43%), Gaps = 16/263 (6%)

Query: 1   MPEKLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDI-DEEAARKAGKELNA-KVFTS 58
           M   ++ GI+G   I      PA+K     A+VVAV    D E A     E +  K +  
Sbjct: 1   MGNNVRWGILGTAGIAKKQLIPAIKRASN-AEVVAVSSRNDMEKANCYADECDIPKRYAR 59

Query: 59  LDEFL-EQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQE 117
            ++ L + D++ V I  P + H   A +A + GKHV+ EKP ALT  EA++M+       
Sbjct: 60  YEDLLNDPDIDAVYIPLPNHLHLTWAKKAAEHGKHVLCEKPAALTAAEAKEMVDACAAHG 119

Query: 118 LKLFVGHVRRFDKRWIQIKDIIKSRNILPMQ-IRKIEVQHLPFPADYWYWDESKSGGVIV 176
           +      + +F  +  ++K +I S  I  ++ IR      LP  A+    +    GG + 
Sbjct: 120 VVFMEAFMYQFHPQHGEVKRLIDSGKIGEVRLIRSNFSFQLPLEANNIRLNREMGGGSLY 179

Query: 177 DLGVHVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWS 236
           D+G +     R+    EP+  +  G  +  E  V+ +   V   ++ EGG T +   S+ 
Sbjct: 180 DVGCYCIHLTRYLTGKEPVHAYGTG-YLHPELGVDTSFTGV---LQMEGGVTSVFTSSFE 235

Query: 237 YPMPPKYGVFYHHLDIIGKNGRI 259
            P    Y       +++G  G I
Sbjct: 236 QPADDSY-------EVVGTEGTI 251


>gb|AAD03557.1| (AF095748) phthalate dihydrodiol dehydrogenase [Burkholderia
           cepacia]
           Length = 391
           
 Score = 73.4 bits (177), Expect = 4e-12
 Identities = 48/192 (25%), Positives = 92/192 (47%), Gaps = 15/192 (7%)

Query: 4   KLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFL 63
           +L++G+ G G  F+L     L+  R   ++VA  D  +EA R+   +  A  +  + E  
Sbjct: 5   RLRIGVAGLGRAFSLMLPTFLRDSRV--QLVAACDPRDEARRQFAADFAAPTYADVAELA 62

Query: 64  -EQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFV 122
            + ++ ++ + +P   HA+    A   GKHV+VEKP+AL   + ++MI       + L V
Sbjct: 63  NDPNVEIIYVASPHQFHAQHTEIAAAKGKHVLVEKPMALAAADCDRMIAACRAANVHLIV 122

Query: 123 GHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPADYWYWDE-------SKSGGVI 175
           GH   FD  +++ +++I   +   +++    +Q + +  DY Y          ++ GG +
Sbjct: 123 GHCHSFDTPYLRTRELISLGDFGAVKM----IQAVNY-TDYLYRPRRPEELATAEGGGAV 177

Query: 176 VDLGVHVTDFLR 187
                H  D +R
Sbjct: 178 FSQAAHQVDIVR 189


>dbj|BAA97119.1| (AB035122) 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase
           [Sphingomonas paucimobilis]
           Length = 315
           
 Score = 73.0 bits (176), Expect = 5e-12
 Identities = 69/255 (27%), Positives = 113/255 (44%), Gaps = 24/255 (9%)

Query: 5   LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFLE 64
           +++ + G G  F   H   LK++  +  V  +    E+AA  A K       T L E L 
Sbjct: 1   MRIALAGAG-AFGEKHLDGLKNIDGVEIVSIISRKAEQAAEVAAKYGAKHSGTDLSEALA 59

Query: 65  QD-MNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVG 123
           +D ++ V + TPT  HAE AI  + AGKHV VE P+A +  +AE ++K+++   L   VG
Sbjct: 60  RDDVDAVILCTPTQMHAEQAIACMNAGKHVQVEIPLADSWADAEAVMKKSQETGLVCMVG 119

Query: 124 HVRRFD--KRWIQIKDIIKSRNILPMQIRKIEVQHLPFPADYWYWDESKSGGVIVDLGVH 181
           H RRF+   ++I  K +     I  M ++    +     A      E +S          
Sbjct: 120 HTRRFNPSHQYIHNKIVAGELAIQQMDVQTYFFRRKNMNAK----GEPRSW--------- 166

Query: 182 VTDFLRWFFESEPIEVFA--VGKAIRGEARVNKTHDH----VVMFIKFEGGKTGIGEVSW 235
            TD L W   +  +++FA   GK ++  A     H      + M I+ +     I  +S 
Sbjct: 167 -TDHLLWHHAAHTVDLFAYQAGKIVQANAVQGPIHPELGIAMDMSIQLKSETGAICTLSL 225

Query: 236 SYPMPPKYGVFYHHL 250
           S+      G F+ ++
Sbjct: 226 SFNNDGPLGTFFRYI 240


>pir||A81396 hypothetical protein Cj0504c [imported] - Campylobacter jejuni
           (strain NCTC 11168) >gi|6967973|emb|CAB75141.1|
           (AL139075) hypothetical protein Cj0504c [Campylobacter
           jejuni]
           Length = 288
           
 Score = 73.0 bits (176), Expect = 5e-12
 Identities = 53/209 (25%), Positives = 105/209 (49%), Gaps = 15/209 (7%)

Query: 5   LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFLE 64
           +K+GIIG G +    H   L S  +  K+ A+ D+ +        ++    +  LD+FL 
Sbjct: 1   MKIGIIGLGKM-GQNHLNEL-SKNSHFKLNALFDLCKNPNLNIFDDI---FYDDLDKFLN 55

Query: 65  QDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVGH 124
           Q+ +++ I TPT +H  +A +  K  K V++EKP+AL ++E +++   A+   +K+ VG 
Sbjct: 56  QNNDIIIIATPTNSHLTIAKKVFKQCKCVLIEKPLALNLKEIDEISNLAKEYSIKVGVGF 115

Query: 125 VRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPADYWYWDESKSGGVIVDLGVHVTD 184
             RF+   + +K  +++  I+ + I++      P+P            G++ DL VH  D
Sbjct: 116 CERFNPAVLALKKELENEEIISINIQRFS----PYP------QRISDVGILQDLAVHDLD 165

Query: 185 FLRWFFESEPIEVFAVGKAIRGEARVNKT 213
            L +  + E  +   + K  + + R +++
Sbjct: 166 LLCFLSKQEITKTNLLKKYTQDQTRESES 194


>pir||T36464 probable oxidoreductase - Streptomyces coelicolor
           >gi|5824085|emb|CAB54161.1| (AL110470) putative
           oxidoreductase [Streptomyces coelicolor A3(2)]
           Length = 417
           
 Score = 72.6 bits (175), Expect = 6e-12
 Identities = 56/221 (25%), Positives = 102/221 (45%), Gaps = 13/221 (5%)

Query: 5   LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTS--LDEF 62
           L+VG++G G   ++A   AL +    A++V+  D D      A +   A V      +  
Sbjct: 12  LRVGVVGVGQRADMA---ALVNRSGAARIVSCADPDPRGREDARRLFGADVVVHDRYERM 68

Query: 63  LEQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFV 122
           L+ +++ V +LTP + H E A+  L AG  V VEKP+ +TV + + ++  A     +L+V
Sbjct: 69  LDDELDAVFVLTPDHLHTEPALCFLAAGVAVFVEKPLTITVADCDALLMAAFRSRTRLYV 128

Query: 123 GHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHL-----PFPADYWYWDESKSGGVIVD 177
           GH  R      +++++I    +   ++R +  +H       F    W+   + + G+++ 
Sbjct: 129 GHNLRHLPVLRRMRELIDDGAV--GRVRAVWCRHFVGHGGDFYFKDWHAQRANTTGLLLQ 186

Query: 178 LGVHVTDFLRWFFESEPIEVFAVGK-AIRGEARVNKTHDHV 217
            G H  D + W        V A G  A+ G+     T + V
Sbjct: 187 KGAHDLDVVHWLAGGFSRNVVAQGALAVYGDNPRRATQETV 227


>pir||B64919 conserved hypothetical protein b1624 - Escherichia coli
           >gi|1742678|dbj|BAA15375.1| (D90805) Virulence factor
           MviM. [Escherichia coli] >gi|1742686|dbj|BAA15382.1|
           (D90806) Virulence factor MviM. [Escherichia coli]
           >gi|1742694|dbj|BAA15389.1| (D90807) Virulence factor
           MviM. [Escherichia coli] >gi|1742718|dbj|BAA15412.1|
           (D90808) Virulence factor MviM. [Escherichia coli]
           >gi|1787911|gb|AAC74696.1| (AE000258) orf, hypothetical
           protein [Escherichia coli K12]
           Length = 359
           
 Score = 71.8 bits (173), Expect = 1e-11
 Identities = 51/185 (27%), Positives = 87/185 (46%), Gaps = 3/185 (1%)

Query: 1   MPEKLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLD 60
           M + ++VG+IG G      H P +    T  + +AV+   +E   KA       V     
Sbjct: 14  MSDNIRVGLIGYGYASKTFHAPLIAG--TPGQELAVISSSDETKVKADWPTVTVVSEPKH 71

Query: 61  EFLEQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKL 120
            F + +++++ I TP  TH  LA  AL+AGKHV+V+KP  +T+ +A ++   A++    L
Sbjct: 72  LFNDPNIDLIVIPTPNDTHFPLAKAALEAGKHVVVDKPFTVTLSQARELDALAKSLGRVL 131

Query: 121 FVGHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHL-PFPADYWYWDESKSGGVIVDLG 179
            V H RR+D  ++ +K ++    +  +   +       P   D W        G+  DL 
Sbjct: 132 SVFHNRRWDSDFLTLKGLLAEGVLGEVAYFESHFDRFRPQVRDRWREQGGPGSGIWYDLA 191

Query: 180 VHVTD 184
            H+ D
Sbjct: 192 PHLLD 196


>sp|P77376|YDGJ_ECOLI HYPOTHETICAL OXIDOREDUCTASE IN ADD-NTH INTERGENIC REGION
           Length = 346
           
 Score = 71.8 bits (173), Expect = 1e-11
 Identities = 51/185 (27%), Positives = 87/185 (46%), Gaps = 3/185 (1%)

Query: 1   MPEKLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLD 60
           M + ++VG+IG G      H P +    T  + +AV+   +E   KA       V     
Sbjct: 1   MSDNIRVGLIGYGYASKTFHAPLIAG--TPGQELAVISSSDETKVKADWPTVTVVSEPKH 58

Query: 61  EFLEQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKL 120
            F + +++++ I TP  TH  LA  AL+AGKHV+V+KP  +T+ +A ++   A++    L
Sbjct: 59  LFNDPNIDLIVIPTPNDTHFPLAKAALEAGKHVVVDKPFTVTLSQARELDALAKSLGRVL 118

Query: 121 FVGHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHL-PFPADYWYWDESKSGGVIVDLG 179
            V H RR+D  ++ +K ++    +  +   +       P   D W        G+  DL 
Sbjct: 119 SVFHNRRWDSDFLTLKGLLAEGVLGEVAYFESHFDRFRPQVRDRWREQGGPGSGIWYDLA 178

Query: 180 VHVTD 184
            H+ D
Sbjct: 179 PHLLD 183


>gb|AAF51262.1| (AE003583) CG3609 gene product [Drosophila melanogaster]
           Length = 335
           
 Score = 70.2 bits (169), Expect = 3e-11
 Identities = 62/234 (26%), Positives = 106/234 (44%), Gaps = 16/234 (6%)

Query: 1   MPEKLKVGIIGCGNI---FNLAHKPALKSLRTIAKVVA-VMDIDEEAARKAGKELNAKVF 56
           M + ++ GI   G I   F +A      S   +  V A  +D  +E A K G     K  
Sbjct: 1   MSKLIRWGIASAGKISEDFVIALSTLPSSDHKVQAVAARALDRAQEFATKHGIP---KAL 57

Query: 57  TSLDEFLEQ-DMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAEN 115
            S +E  +  D++VV I T    H E+A+  L  GKHV+ EKP+A+  ++ E ++  A+ 
Sbjct: 58  GSYEELAKSTDVDVVYIGTLNPQHYEVALLMLNNGKHVLCEKPLAMNKKQVEGILAAAKA 117

Query: 116 QELKLFVGHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQH-LPFPADYWYWDESKSGGV 174
            +         RF   + ++K++I S  +   Q++ +EV    P P           GGV
Sbjct: 118 NKRFFMEAVWSRFFPSYQRVKELISSGQL--GQVKDVEVNFGFPMPHVDRLQKRELGGGV 175

Query: 175 IVDLGVHVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKT 228
           + DLG++     +W F+ +P ++ +     +G        D V   + + GG+T
Sbjct: 176 VYDLGIYTIQVSQWAFQEKPEKIES-----KGTLNAEGIDDDVSATLTYSGGRT 224


>sp|Q44258|CBAC_ALCSB 1-CARBOXY-3-CHLORO-3,4-DIHYDROXYCYCLO HEXA-1,5-DIENE DEHYDROGENASE
           >gi|2073552|gb|AAC45718.1| (U18133)
           1-carboxy-3-chloro-3,4-dihydroxycyclohexa-1,5-diene
           dehydrogenase [Comamonas testosteroni]
           Length = 397
           
 Score = 69.9 bits (168), Expect = 4e-11
 Identities = 59/202 (29%), Positives = 91/202 (44%), Gaps = 16/202 (7%)

Query: 5   LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFL- 63
           +++G++G G  F L     L   R   ++VA  D D  + R+   +  A       E L 
Sbjct: 1   MRIGVVGLGKAFMLMLPTFLMDRRV--QLVAASDTDPLSLRQFKADFPAAAVHGDIESLC 58

Query: 64  -EQDMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFV 122
              D+ VV I TP   HA  A  AL AGKHV+VEKP+A+T+E+  +M   A+     L V
Sbjct: 59  KNPDVEVVYIGTPHQFHAVHAEIALNAGKHVLVEKPMAVTLEDCCRMNACAQRAGKYLIV 118

Query: 123 GHVRRFDKRWIQIKDIIKSRNILPMQIRKIEVQHLPFPADYWY-------WDESKSGGVI 175
           GH   FD    + K++I S      +  ++   H     D+ Y        +    GGV+
Sbjct: 119 GHSHSFDHPISRAKELIDSG-----RYGRVRFIHSMNYTDFLYRPRRAEELNTDLGGGVV 173

Query: 176 VDLGVHVTDFLRWFFESEPIEV 197
            +   H  D +R   +   ++V
Sbjct: 174 FNQASHQLDVIRLLAQGRVVDV 195


>sp|P09400|STRI_STRGR STREPTOMYCIN BIOSYNTHESIS PROTEIN STRI >gi|80803|pir||S17779 strI
           protein - Streptomyces griseus >gi|49268|emb|CAA68521.1|
           (Y00459) NAD:myo-inositol oxidoreductase [Streptomyces
           griseus]
           Length = 348
           
 Score = 69.1 bits (166), Expect = 7e-11
 Identities = 77/349 (22%), Positives = 142/349 (40%), Gaps = 31/349 (8%)

Query: 5   LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNA--KVFTSLDEF 62
           ++VGI+G G +  L H   L  L     +V V D+D + A +  +EL A  K   +++  
Sbjct: 1   MRVGIVGAGRMGRL-HARTLLELPDPPDLV-VHDVDPDGAHRLAQELAAGTKAQVTVERE 58

Query: 63  LEQDM---NVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELK 119
           L   +   + + + TP        + A +AG  V  EKP+     EA ++++   +   +
Sbjct: 59  LADTVTKADAIVVATPATQRRAPLLAAARAGLPVFCEKPLTADETEAAELVEALAH--TR 116

Query: 120 LFVGHVRRFDKRWIQIKDIIKSRNI-LPMQIRKIEVQHLPFPADYWYWDESKSGGVIVDL 178
           L VG  RR D  + +++++I +  +   + +R     H P PAD +   E  +G +  D 
Sbjct: 117 LHVGFQRRCDPEYQRLRELIAAGELGRVLLVRCTAFDHRP-PADAY---EETAGDIFTDC 172

Query: 179 GVHVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTHDHVVMFIKFEGGKTGIGEVSWSYP 238
            +H  D + W      + V A G  +         +D     +    G   +   S   P
Sbjct: 173 LIHDIDAVHWLTGQPTVAVQADGARL----LAGSGYDVATAVLTLADGARAVLSASRLDP 228

Query: 239 MPPKYGVFYHHLDIIGKNGRIRY-----TP---MDTPVVGVVKSSFEMPRFSPMLSTFPQ 290
               +G + H ++++G  G +       TP   +     G        P +      F  
Sbjct: 229 ----HG-YDHRVEVLGTKGSLSVGLDARTPLRLLGQDGTGCPPGPGAQPAYQDFTDRFEA 283

Query: 291 AFEAELRHFFECIKSSCEPVVTAQDALIALKIAEKAKESIKKGEPVKVE 339
           A+  E+  F   +        T Q+AL A ++A  A  + + G  V+++
Sbjct: 284 AYRREVLAFVRTVTEGAPSPCTGQEALRAQRVAAAAGRAARTGTRVELD 332


>dbj|BAB04427.1| (AP001509) unknown conserved protein [Bacillus halodurans]
           Length = 369
           
 Score = 69.1 bits (166), Expect = 7e-11
 Identities = 42/120 (35%), Positives = 70/120 (58%), Gaps = 5/120 (4%)

Query: 5   LKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFLE 64
           +K G+IGCGNI ++  +   +       +VA  D+  E AR   ++       ++ E LE
Sbjct: 4   IKAGLIGCGNISSIYFENVHRFKHLT--IVACADLHLERARAQAEKYRIPKACTVAELLE 61

Query: 65  Q-DMNVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVG 123
             ++ +V  LT    HA++ I+AL+AGKHV  EKP+ +T+EE +K++++A  +E  L VG
Sbjct: 62  DPEIELVINLTIPQVHAKVCIQALEAGKHVYTEKPLTITLEEGQKLLEKA--KETGLLVG 119


>pir||T42744 hypothetical protein - fission yeast (Schizosaccharomyces pombe)
           (fragment) >gi|1749580|dbj|BAA13848.1| (D89186) similar
           to Escherichia coli hypothetical 38.8KD protein in
           GNTR-GGT intergenic region, SWISS-PROT Accession Number
           P46853 [Schizosaccharomyces pombe]
           Length = 352
           
 Score = 68.7 bits (165), Expect = 9e-11
 Identities = 49/169 (28%), Positives = 82/169 (47%), Gaps = 4/169 (2%)

Query: 20  HKPALKSLRTIAKVVAVMDIDEEAARKAGKE--LNAKVFTSLDEFL-EQDMNVVEILTPT 76
           H P LK+L    +V A  +    +     +    N KV+T LDE L + ++ +V I  P 
Sbjct: 2   HYPFLKALPNHFEVYAAWERRATSTESKARADFPNVKVYTKLDELLADSNIELVVISLPP 61

Query: 77  YTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKLFVGHVRRFDKRWIQIK 136
             H E+  +AL  GKHV+ EKP   T  EA+++   A+++ L L +   RRFD  ++  K
Sbjct: 62  NVHYEVVSQALNVGKHVLCEKPFTPTYGEAKELFDLAKSKNLMLTLYQNRRFDGDFLTAK 121

Query: 137 DIIKSRNILPMQIRKIEVQHLP-FPADYWYWDESKSGGVIVDLGVHVTD 184
           + I++  +  +   +  +     F    W    +   G++ DLG H+ D
Sbjct: 122 ECIENGRLGEVVQFESHIDRFRLFRKGNWKDVPNPGCGLVYDLGSHLID 170


>gb|AAF97051.1| (AF248034) WlbA [Bordetella avium]
           Length = 125
           
 Score = 68.7 bits (165), Expect = 9e-11
 Identities = 40/118 (33%), Positives = 65/118 (54%), Gaps = 2/118 (1%)

Query: 4   KLKVGIIGCGNIFNLAHKPALKSLRTIAKVVAVMDIDEEAARKAGKELNAKVFTSLDEFL 63
           K++  ++GCG I +  H  A+      A++V V D D  A R A K   AK ++SL E L
Sbjct: 8   KIRFALVGCGRI-SKNHIAAIAQHHERAELVEVCDTDPAALRAAAKATGAKPYSSLSEML 66

Query: 64  EQDM-NVVEILTPTYTHAELAIEALKAGKHVIVEKPIALTVEEAEKMIKEAENQELKL 120
                + V + TP+  H   AIE  ++G+HV+ EKP+A   E+ ++M+K  ++  + L
Sbjct: 67  AASTADAVILATPSGLHPWQAIEVAQSGRHVVSEKPMATRWEDGKRMVKACDDAGVHL 124


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.321    0.138    0.406 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 126048172
Number of Sequences: 2977
Number of extensions: 5310718
Number of successful extensions: 12960
Number of sequences better than 1.0e-10: 67
Number of HSP's better than  0.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 62
Number of HSP's that attempted gapping in prelim test: 12855
Number of HSP's gapped (non-prelim): 76
length of query: 341
length of database: 189,106,746
effective HSP length: 55
effective length of query: 286
effective length of database: 156,189,961
effective search space: 44670328846
effective search space used: 44670328846
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 165 (68.7 bits)