BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB1159 (gcp) DE:O-sialoglycoprotein endopeptidase (gcp) (324 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||F75029 o-sialoglycoprotein endopeptidase (gcp) PAB1159 - Py... 644 0.0 sp|O57716|GCP_PYRHO PUTATIVE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (... 611 e-174 gi|11498712 O-sialoglycoprotein endopeptidase (gcp) [Archaeoglob... 394 e-109 sp|O27476|GCP_METTH PUTATIVE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (... 386 e-106 pir||A64441 O-sialoglycoprotein endopeptidase (EC 3.4.24.57) hom... 364 e-100 sp|Q58530|GCP_METJA PUTATIVE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (... 364 e-100 emb|CAC11469.1| (AL445064) O-sialoglycoprotein endopeptidase rel... 353 2e-96 pir||T04567 O-sialoglycoprotein endopeptidase homolog T12H17.110... 316 2e-85 gb|AAF49481.1| (AE003527) CG4933 gene product [Drosophila melano... 307 9e-83 gi|8923380 hypothetical protein FLJ20411 [Homo sapiens] >gi|1143... 306 3e-82 pir||T39567 glycoprotein endopeptidase-like protein - fission ye... 303 2e-81 pir||H72714 probable O-sialoglycoprotein endopeptidase APE1135 -... 290 1e-77 dbj|BAA82123.1| (AB023065) O-sialoglycoprotease [Rattus norvegicus] 283 2e-75 gi|6322891 probable calcium-binding protein; Ykr038cp [Saccharom... 263 2e-69 gb|AAG20204.1| (AE005096) O-sialoglycoprotein endopeptidase homo... 244 1e-63 gb|AAK40758.1| O-sialoglycoprotein endopeptidase [Sulfolobus sol... 215 7e-55 sp|P43764|GCP_HAEIN PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (... 192 6e-48 sp|P36174|YHSH_HALMA HYPOTHETICAL PROTEIN IN HSH 3'REGION (ORFX)... 190 1e-47 sp|O66986|GCP_AQUAE PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (... 190 2e-47 sp|O05518|GCP_BACSU PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (... 188 7e-47 pir||G72411 hypothetical protein TM0145 - Thermotoga maritima (s... 182 5e-45 pir||QQECR6 O-sialoglycoprotein endopeptidase (EC 3.4.24.57) - E... 177 1e-43 sp|P05852|GCP_ECOLI PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (... 175 5e-43 sp|O86793|GCP_STRCO PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (... 175 5e-43 pir||H83572 O-sialoglycoprotein endopeptidase PA0580 [imported] ... 173 2e-42 dbj|BAB04267.1| (AP001508) glycoprotein endopeptidase [Bacillus ... 173 2e-42 pir||D82807 O-sialoglycoprotein endopeptidase XF0435 [imported] ... 172 4e-42 pir||C81986 probable O-sialoglycoprotein endopeptidase (EC 3.4.2... 169 4e-41 sp|P36175|GCP_PASHA O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROT... 169 5e-41 pir||C81040 O-sialoglycoprotein endopeptidase NMB1802 [imported]... 168 6e-41 gb|AAF32396.1|AF224466_3 (AF224466) sialylglycoprotease [Haemoph... 166 4e-40 sp|P74034|GCP_SYNY3 PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (... 164 1e-39 gb|AAB82636.1| (AC002387) putative O-sialoglycoprotein endopepti... 155 6e-37 sp|O51710|GCP_BORBU PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (... 152 4e-36 pir||A71545 probable o-sialoglycoprotein endopeptidase - Chlamyd... 149 5e-35 pir||H72106 o-sialoglycoprotein endopeptidase - Chlamydophila pn... 148 6e-35 sp|Q50709|GCP_MYCTU PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (... 143 3e-33 sp|P57166|GCP_BUCAI PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (... 143 3e-33 gb|AAF73560.1| (AE002315) O-sialoglycoprotein endopeptidase [Chl... 143 4e-33 sp|Q9ZEA8|GCP_RICPR PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (... 141 1e-32 sp|P37969|GCP_MYCLE PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (... 133 2e-30 sp|O83686|GCP_TREPA PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (... 125 5e-28 gi|6320099 similar to H.influenzae sialoglycoprotease; Qri7p [Sa... 124 1e-27 sp|P75055|GCP_MYCPN PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (... 123 3e-27 sp|P47292|GCP_MYCGE PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (... 115 1e-24 pir||S72996 probable glycoproteinase u229e - Mycobacterium lepra... 112 6e-24 gi|11641265 putative sialoglycoprotease type 2 [Homo sapiens] >g... 110 2e-23 pir||T40899 probable proteinase - fission yeast (Schizosaccharom... 109 6e-23 pir||T18825 hypothetical protein C01G10.10 - Caenorhabditis eleg... 103 3e-21 pir||H82894 sialoglycoproteinase UU411 [imported] - Ureaplasma u... 101 1e-20 pir||E81278 probable glycoproteinase Cj1344c [imported] - Campyl... 99 6e-20 gb|AAF49008.1| (AE003513) CG14231 gene product [Drosophila melan... 97 2e-19 pir||E71801 probable o-sialoglycoprotein endopeptidase - Helicob... 95 1e-18 gb|AAD00282.1| (U78601) putative sialoglycoprotease protein [Str... 94 2e-18 sp|P55996|GCP_HELPY PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (... 93 5e-18 >pir||F75029 o-sialoglycoprotein endopeptidase (gcp) PAB1159 - Pyrococcus abyssi (strain Orsay) >gi|5459190|emb|CAB50676.1| (AJ248288) O-sialoglycoprotein endopeptidase (gcp) [Pyrococcus abyssi] Length = 324 Score = 644 bits (1642), Expect = 0.0 Identities = 324/324 (100%), Positives = 324/324 (100%) Query: 1 MLALGIEGTAHTLGIGIVSEDKVLANVFDTLTTEKGGIHPKEAAEHHARLMKPLLRKALS 60 MLALGIEGTAHTLGIGIVSEDKVLANVFDTLTTEKGGIHPKEAAEHHARLMKPLLRKALS Sbjct: 1 MLALGIEGTAHTLGIGIVSEDKVLANVFDTLTTEKGGIHPKEAAEHHARLMKPLLRKALS 60 Query: 61 EAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKMFGV 120 EAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKMFGV Sbjct: 61 EAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKMFGV 120 Query: 121 KDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGPKVEKLAE 180 KDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGPKVEKLAE Sbjct: 121 KDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGPKVEKLAE 180 Query: 181 KGEKYIELPYAVKGMDLSFSGLLTEAIRKYRSGKYRVEDLAYSFQETAFAALVEVTERAV 240 KGEKYIELPYAVKGMDLSFSGLLTEAIRKYRSGKYRVEDLAYSFQETAFAALVEVTERAV Sbjct: 181 KGEKYIELPYAVKGMDLSFSGLLTEAIRKYRSGKYRVEDLAYSFQETAFAALVEVTERAV 240 Query: 241 AHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGLRMYKA 300 AHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGLRMYKA Sbjct: 241 AHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGLRMYKA 300 Query: 301 GISFRLEETIVKQKFRTDEVEIVW 324 GISFRLEETIVKQKFRTDEVEIVW Sbjct: 301 GISFRLEETIVKQKFRTDEVEIVW 324 >sp|O57716|GCP_PYRHO PUTATIVE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROTEASE) >gi|7444716|pir||C71215 O-sialoglycoprotein endopeptidase homolog PH1987 - Pyrococcus horikoshii >gi|3258431|dbj|BAA31114.1| (AP000007) 324aa long hypothetical O-sialoglycoprotein endopeptidase [Pyrococcus horikoshii] Length = 324 Score = 611 bits (1558), Expect = e-174 Identities = 301/324 (92%), Positives = 316/324 (96%) Query: 1 MLALGIEGTAHTLGIGIVSEDKVLANVFDTLTTEKGGIHPKEAAEHHARLMKPLLRKALS 60 MLALGIEGTAHTLGIGIVSE KVLANVFDTLTTEKGGIHPKEAAEHHARLMKPLL+KAL Sbjct: 1 MLALGIEGTAHTLGIGIVSEKKVLANVFDTLTTEKGGIHPKEAAEHHARLMKPLLKKALE 60 Query: 61 EAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKMFGV 120 +AG+S+DDIDVIAFSQGPGLGPALRVVATAARALA++Y KPIVGVNHCIAHVEITKMFG+ Sbjct: 61 KAGISMDDIDVIAFSQGPGLGPALRVVATAARALAIRYNKPIVGVNHCIAHVEITKMFGI 120 Query: 121 KDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGPKVEKLAE 180 KDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGPK+EKLAE Sbjct: 121 KDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGPKLEKLAE 180 Query: 181 KGEKYIELPYAVKGMDLSFSGLLTEAIRKYRSGKYRVEDLAYSFQETAFAALVEVTERAV 240 KG+ YI+LPYAVKGMDLSFSGLLTEAIRKYRSGK+RVEDLAYSFQETAFAALVEVTERA+ Sbjct: 181 KGKNYIDLPYAVKGMDLSFSGLLTEAIRKYRSGKFRVEDLAYSFQETAFAALVEVTERAL 240 Query: 241 AHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGLRMYKA 300 AHTEK EVVLVGGVAANNRLREML+IM EDRG+KFFVPPYDLCRDNGAMIAYTGLRMYKA Sbjct: 241 AHTEKKEVVLVGGVAANNRLREMLKIMAEDRGVKFFVPPYDLCRDNGAMIAYTGLRMYKA 300 Query: 301 GISFRLEETIVKQKFRTDEVEIVW 324 GISF LE+TIVKQKFRTDEVEI W Sbjct: 301 GISFPLEKTIVKQKFRTDEVEITW 324 >gi|11498712 O-sialoglycoprotein endopeptidase (gcp) [Archaeoglobus fulgidus] >gi|7444721|pir||G69388 O-sialoglycoprotein endopeptidase homolog - Archaeoglobus fulgidus >gi|2649475|gb|AAB90129.1| (AE001027) O-sialoglycoprotein endopeptidase (gcp) [Archaeoglobus fulgidus] Length = 323 Score = 394 bits (1001), Expect = e-109 Identities = 199/325 (61%), Positives = 251/325 (77%), Gaps = 4/325 (1%) Query: 1 MLALGIEGTAHTLGIGIVSEDKVLANVFDTLTTEKGGIHPKEAAEHHARLMKPLLRKALS 60 M+ALGIEGTA +L IG+V E+ V+A D ++GGIHP+EA++HH+ + LL + Sbjct: 1 MIALGIEGTAWSLSIGVVDEEGVIALENDPYIPKEGGIHPREASQHHSERLPSLLSRVFE 60 Query: 61 EAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITK-MFG 119 + V + IDV+AFSQGPG+GP LRVVATAAR LA+K KP+VGVNHC+AHVE+ + G Sbjct: 61 K--VDKNSIDVVAFSQGPGMGPCLRVVATAARLLAIKLEKPLVGVNHCLAHVEVGRWQTG 118 Query: 120 VKDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGPKVEKLA 179 + PV LYVSGGN+QV+A G RYRVFGETLDIGIGNA+D AR +GL PGGPK+E+LA Sbjct: 119 ARKPVSLYVSGGNSQVIARRGNRYRVFGETLDIGIGNALDKLARHMGLKHPGGPKIEELA 178 Query: 180 EKGEKYIELPYAVKGMDLSFSGLLTEAIRKYRSGKYRVEDLAYSFQETAFAALVEVTERA 239 +KG+KY LPY VKGMD SFSG++T A R + SG R+ED+A+SFQETAFA L EVTERA Sbjct: 179 KKGQKYHFLPYVVKGMDFSFSGMVTAAQRLFDSG-VRMEDVAFSFQETAFAMLTEVTERA 237 Query: 240 VAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGLRMYK 299 +A+ + +EV+LVGGVAAN RL+EMLRIM EDRG KF+VPP +L DNGAMIAYTGL MYK Sbjct: 238 LAYLDLNEVLLVGGVAANKRLQEMLRIMCEDRGAKFYVPPKELAGDNGAMIAYTGLLMYK 297 Query: 300 AGISFRLEETIVKQKFRTDEVEIVW 324 G +E++ V+ FR ++VE+ W Sbjct: 298 HGHQTPVEKSYVRPDFRIEDVEVNW 322 >sp|O27476|GCP_METTH PUTATIVE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROTEASE) >gi|7482768|pir||H69056 O-sialoglycoprotein endopeptidase - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622538|gb|AAB85902.1| (AE000904) O-sialoglycoprotein endopeptidase [Methanobacterium thermoautotrophicum] Length = 534 Score = 386 bits (981), Expect = e-106 Identities = 199/326 (61%), Positives = 246/326 (75%), Gaps = 3/326 (0%) Query: 1 MLALGIEGTAHTLGIGIVSE-DKVLANVFDTLTTEKGGIHPKEAAEHHARLMKPLLRKAL 59 ML LGIEGTA G+GIV E VL+ L EKGGIHP+EAAEHHA+ + L+ +A Sbjct: 1 MLCLGIEGTAEKTGVGIVDEAGNVLSLRGKPLIPEKGGIHPREAAEHHAKWIPRLIAEAC 60 Query: 60 SEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKMF- 118 +AGV L +I +I+FS+GPGLGPALR VATAAR LA+ PIVGVNHCI H+EI ++ Sbjct: 61 RDAGVELGEIGLISFSRGPGLGPALRTVATAARTLALSLDVPIVGVNHCIGHIEIGRLTT 120 Query: 119 GVKDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGPKVEKL 178 G DPV LYVSGGNTQV+A GRYRVFGETLDI +GN +D FARE GLG PGGP +E+L Sbjct: 121 GASDPVSLYVSGGNTQVIAFNEGRYRVFGETLDIAVGNMLDQFARESGLGHPGGPVIEQL 180 Query: 179 AEKGEKYIELPYAVKGMDLSFSGLLTEAIRKYRSGKYRVEDLAYSFQETAFAALVEVTER 238 A K +YIELPY+VKGMD+SFSGLLT A+RK +G +EDLAYS QETAF+ LVEVTER Sbjct: 181 ALKASEYIELPYSVKGMDISFSGLLTAALRKMEAGA-SLEDLAYSIQETAFSMLVEVTER 239 Query: 239 AVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGLRMY 298 A+A+TEK++V+L GGVA N RLR+MLR M ++ ++F +PP + C DNGAMIA+ G +Y Sbjct: 240 ALAYTEKNQVLLCGGVAVNRRLRDMLREMCQEHHVEFHMPPPEYCGDNGAMIAWLGQLVY 299 Query: 299 KAGISFRLEETIVKQKFRTDEVEIVW 324 K LE+T V Q++RTDEV++ W Sbjct: 300 KYRGPDALEDTTVVQRYRTDEVDVPW 325 >pir||A64441 O-sialoglycoprotein endopeptidase (EC 3.4.24.57) homolog - Methanococcus jannaschii Length = 539 Score = 364 bits (924), Expect = e-100 Identities = 185/326 (56%), Positives = 240/326 (72%), Gaps = 5/326 (1%) Query: 1 MLALGIEGTAHTLGIGIVSED-KVLANVFDTLTTEKGGIHPKEAAEHHARLMKPLLRKAL 59 M+ LG+EGTA G+GIV+ D +VL N K GI+P+EAA+HHA L+++A Sbjct: 5 MICLGLEGTAEKTGVGIVTSDGEVLFNKTIMYKPPKQGINPREAADHHAETFPKLIKEAF 64 Query: 60 SEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKMFG 119 V ++ID+IAFSQGPGLGP+LRV AT AR L++ +KPI+GVNHCIAH+EI K+ Sbjct: 65 EV--VDKNEIDLIAFSQGPGLGPSLRVTATVARTLSLTLKKPIIGVNHCIAHIEIGKLTT 122 Query: 120 -VKDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGPKVEKL 178 +DP+ LYVSGGNTQV+A +YRVFGETLDI +GN +D FAR + L PGGP +E+L Sbjct: 123 EAEDPLTLYVSGGNTQVIAYVSKKYRVFGETLDIAVGNCLDQFARYVNLPHPGGPYIEEL 182 Query: 179 AEKGEKYIELPYAVKGMDLSFSGLLTEAIRKYRSGKYRVEDLAYSFQETAFAALVEVTER 238 A KG+K ++LPY VKGMD++FSGLLT A+R Y +G+ R+ED+ YS QE AF+ L E+TER Sbjct: 183 ARKGKKLVDLPYTVKGMDIAFSGLLTAAMRAYDAGE-RLEDICYSLQEYAFSMLTEITER 241 Query: 239 AVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGLRMY 298 A+AHT K EV+LVGGVAANNRLREML+ M E + + F+VPP + C DNGAMIA+ GL M+ Sbjct: 242 ALAHTNKGEVMLVGGVAANNRLREMLKAMCEGQNVDFYVPPKEFCGDNGAMIAWLGLLMH 301 Query: 299 KAGISFRLEETIVKQKFRTDEVEIVW 324 K G L+ET + +RTD VE+ W Sbjct: 302 KNGRWMSLDETKIIPNYRTDMVEVNW 327 >sp|Q58530|GCP_METJA PUTATIVE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROTEASE) >gi|2826367|gb|AAB99132.1| (U67555) O-sialoglycoprotein endopeptidase (gcp) [Methanococcus jannaschii] Length = 535 Score = 364 bits (924), Expect = e-100 Identities = 185/326 (56%), Positives = 240/326 (72%), Gaps = 5/326 (1%) Query: 1 MLALGIEGTAHTLGIGIVSED-KVLANVFDTLTTEKGGIHPKEAAEHHARLMKPLLRKAL 59 M+ LG+EGTA G+GIV+ D +VL N K GI+P+EAA+HHA L+++A Sbjct: 1 MICLGLEGTAEKTGVGIVTSDGEVLFNKTIMYKPPKQGINPREAADHHAETFPKLIKEAF 60 Query: 60 SEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKMFG 119 V ++ID+IAFSQGPGLGP+LRV AT AR L++ +KPI+GVNHCIAH+EI K+ Sbjct: 61 EV--VDKNEIDLIAFSQGPGLGPSLRVTATVARTLSLTLKKPIIGVNHCIAHIEIGKLTT 118 Query: 120 -VKDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGPKVEKL 178 +DP+ LYVSGGNTQV+A +YRVFGETLDI +GN +D FAR + L PGGP +E+L Sbjct: 119 EAEDPLTLYVSGGNTQVIAYVSKKYRVFGETLDIAVGNCLDQFARYVNLPHPGGPYIEEL 178 Query: 179 AEKGEKYIELPYAVKGMDLSFSGLLTEAIRKYRSGKYRVEDLAYSFQETAFAALVEVTER 238 A KG+K ++LPY VKGMD++FSGLLT A+R Y +G+ R+ED+ YS QE AF+ L E+TER Sbjct: 179 ARKGKKLVDLPYTVKGMDIAFSGLLTAAMRAYDAGE-RLEDICYSLQEYAFSMLTEITER 237 Query: 239 AVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGLRMY 298 A+AHT K EV+LVGGVAANNRLREML+ M E + + F+VPP + C DNGAMIA+ GL M+ Sbjct: 238 ALAHTNKGEVMLVGGVAANNRLREMLKAMCEGQNVDFYVPPKEFCGDNGAMIAWLGLLMH 297 Query: 299 KAGISFRLEETIVKQKFRTDEVEIVW 324 K G L+ET + +RTD VE+ W Sbjct: 298 KNGRWMSLDETKIIPNYRTDMVEVNW 323 >emb|CAC11469.1| (AL445064) O-sialoglycoprotein endopeptidase related protein [Thermoplasma acidophilum] Length = 529 Score = 353 bits (895), Expect = 2e-96 Identities = 174/325 (53%), Positives = 234/325 (71%), Gaps = 2/325 (0%) Query: 1 MLALGIEGTAHTLGIGIVSEDKVLANVFDTLTTEKGGIHPKEAAEHHARLMKPLLRKALS 60 M+ LG+EGTAHT+ GI+ E ++LA + GGI P +AA HH+ ++ ++ +AL Sbjct: 1 MIVLGLEGTAHTISCGIIDESRILAMESSMYRPKTGGIRPLDAAVHHSEVIDTVISRALE 60 Query: 61 EAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEI-TKMFG 119 +A +S+ DID+I FS GPGL P+LRV ATAAR ++V KPI+GVNH + H+EI ++ G Sbjct: 61 KAKISIHDIDLIGFSMGPGLAPSLRVTATAARTISVLTGKPIIGVNHPLGHIEIGRRVTG 120 Query: 120 VKDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGPKVEKLA 179 DPV LYVSGGNTQV+A GRYRV GETLDIGIGN ID FARE G+ FPGGP++EKLA Sbjct: 121 AIDPVMLYVSGGNTQVIAHVNGRYRVLGETLDIGIGNMIDKFAREAGIPFPGGPEIEKLA 180 Query: 180 EKGEKYIELPYAVKGMDLSFSGLLTEAIRKYRSGKYRVEDLAYSFQETAFAALVEVTERA 239 KG K ++LPY+VKGMD +FSG+LT A++ ++G+ +ED++YS QETAFA LVEV ERA Sbjct: 181 MKGTKLLDLPYSVKGMDTAFSGILTAALQYLKTGQ-AIEDISYSIQETAFAMLVEVLERA 239 Query: 240 VAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGLRMYK 299 + + KDE+++ GGVA N RLR+M+ M + GI+ ++ + C DNG MIA L MYK Sbjct: 240 LYVSGKDEILMAGGVALNRRLRDMVTNMAREAGIRSYLTDREYCMDNGIMIAQAALLMYK 299 Query: 300 AGISFRLEETIVKQKFRTDEVEIVW 324 +G+ +EET V +FR DEV+ W Sbjct: 300 SGVRMSVEETAVNPRFRIDEVDAPW 324 >pir||T04567 O-sialoglycoprotein endopeptidase homolog T12H17.110 - Arabidopsis thaliana >gi|2827549|emb|CAA16557.1| (AL021635) glycoprotein endopeptidase - like protein [Arabidopsis thaliana] >gi|7269118|emb|CAB79227.1| (AL161557) glycoprotein endopeptidase-like protein [Arabidopsis thaliana] Length = 353 Score = 316 bits (802), Expect = 2e-85 Identities = 167/333 (50%), Positives = 225/333 (67%), Gaps = 9/333 (2%) Query: 1 MLALGIEGTAHTLGIGIVSED-KVLANVFDTLTTEKG-GIHPKEAAEHHARLMKPLLRKA 58 M+A+G EG+A+ +G+GIV+ D +LAN T T G G P+E A HH + PL++ A Sbjct: 5 MIAIGFEGSANKIGVGIVTLDGTILANPRHTYITPPGHGFLPRETAHHHLDHVLPLVKSA 64 Query: 59 LSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKMF 118 L + V+ ++ID I +++GPG+G L+V A R L+ ++KPIV VNHC+AH+E+ ++ Sbjct: 65 LETSQVTPEEIDCICYTKGPGMGAPLQVSAIVVRVLSQLWKKPIVAVNHCVAHIEMGRVV 124 Query: 119 -GVKDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGP--KV 175 G DPV LYVSGGNTQV+A GRYR+FGET+DI +GN +D FAR L L P + Sbjct: 125 TGADDPVVLYVSGGNTQVIAYSEGRYRIFGETIDIAVGNCLDRFARVLKLSNDPSPGYNI 184 Query: 176 EKLAEKGEKYIELPYAVKGMDLSFSGLL----TEAIRKYRSGKYRVEDLAYSFQETAFAA 231 E+LA+KGE +I+LPYAVKGMD+SFSG+L T A K ++ + DL YS QET FA Sbjct: 185 EQLAKKGENFIDLPYAVKGMDVSFSGILSYIETTAEEKLKNNECTPADLCYSLQETVFAM 244 Query: 232 LVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIA 291 LVE+TERA+AH +K +V++VGGV N RL+EM+R M +R K F C DNGAMIA Sbjct: 245 LVEITERAMAHCDKKDVLIVGGVGCNERLQEMMRTMCSERDGKLFATDDRYCIDNGAMIA 304 Query: 292 YTGLRMYKAGISFRLEETIVKQKFRTDEVEIVW 324 YTGL + GI +E++ Q+FRTDEV VW Sbjct: 305 YTGLLAFVNGIETPIEDSTFTQRFRTDEVHAVW 337 >gb|AAF49481.1| (AE003527) CG4933 gene product [Drosophila melanogaster] Length = 347 Score = 307 bits (779), Expect = 9e-83 Identities = 163/341 (47%), Positives = 218/341 (63%), Gaps = 19/341 (5%) Query: 3 ALGIEGTAHTLGIGIVSEDKVLANVFDTLTTEKG-GIHPKEAAEHHARLMKPLLRKALSE 61 ALGIEG+A+ +GIGI+ + KVLANV T T G G PKE A+HH + L+ +L E Sbjct: 4 ALGIEGSANKIGIGIIRDGKVLANVRRTYITPPGEGFLPKETAKHHREAILGLVESSLKE 63 Query: 62 AGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKMF-GV 120 A + D+DVI +++GPG+ P L V A AR L++ + P++GVNHCI H+E+ ++ G Sbjct: 64 AQLKSSDLDVICYTKGPGMAPPLLVGAIVARTLSLLWNIPLLGVNHCIGHIEMGRLITGA 123 Query: 121 KDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGP--KVEKL 178 ++P LYVSGGNTQV+A RYR+FGET+DI +GN +D FAR + L P +E+L Sbjct: 124 QNPTVLYVSGGNTQVIAYSNKRYRIFGETIDIAVGNCLDRFARIIKLSNDPSPGYNIEQL 183 Query: 179 AEKGEKYIELPYAVKGMDLSFSGLLTEAIRKYRSGK---------------YRVEDLAYS 223 A+ +YI+LPY VKGMD+SFSG+L+ GK Y DL YS Sbjct: 184 AKSSNRYIKLPYVVKGMDVSFSGILSYIEDLAEPGKRQNKRKKPQEEEVNNYSQADLCYS 243 Query: 224 FQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLC 283 QET FA LVE+TERA+AH +EV++VGGV N RL+EM+RIM E+RG K F C Sbjct: 244 LQETIFAMLVEITERAMAHCGSNEVLIVGGVGCNERLQEMMRIMCEERGGKLFATDERYC 303 Query: 284 RDNGAMIAYTGLRMYKAGISFRLEETIVKQKFRTDEVEIVW 324 DNG MIA+ G M+++G EE+ V Q+FRTDEV + W Sbjct: 304 IDNGLMIAHAGAEMFRSGTRMPFEESYVTQRFRTDEVLVSW 344 >gi|8923380 hypothetical protein FLJ20411 [Homo sapiens] >gi|11437426|ref|XP_007489.1| hypothetical protein FLJ20411 [Homo sapiens] >gi|6850969|emb|CAB71031.1| (AJ271669) putative sialoglycoprotease [Homo sapiens] >gi|7020492|dbj|BAA91150.1| (AK000418) unnamed protein product [Homo sapiens] Length = 335 Score = 306 bits (775), Expect = 3e-82 Identities = 158/329 (48%), Positives = 219/329 (66%), Gaps = 8/329 (2%) Query: 4 LGIEGTAHTLGIGIVSEDKVLANVFDTLTTEKG-GIHPKEAAEHHARLMKPLLRKALSEA 62 LG EG+A+ +G+G+V + KVLAN T T G G P + A HH ++ LL++AL+E+ Sbjct: 5 LGFEGSANKIGVGVVRDGKVLANPRRTYVTPPGTGFLPGDTARHHRAVILDLLQEALTES 64 Query: 63 GVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKMF-GVK 121 G++ DID IA+++GPG+G L VA AR +A + KP+VGVNHCI H+E+ ++ G Sbjct: 65 GLTSQDIDCIAYTKGPGMGAPLVSVAVVARTVAQLWNKPLVGVNHCIGHIEMGRLITGAT 124 Query: 122 DPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGP--KVEKLA 179 P LYVSGGNTQV+A RYR+FGET+DI +GN +D FAR L + P +E++A Sbjct: 125 SPTVLYVSGGNTQVIAYSEHRYRIFGETIDIAVGNCLDRFARVLKISNDPSPGYNIEQMA 184 Query: 180 EKGEKYIELPYAVKGMDLSFSGLLT----EAIRKYRSGKYRVEDLAYSFQETAFAALVEV 235 ++G+K +ELPY VKGMD+SFSG+L+ A R +G+ EDL +S QET FA LVE+ Sbjct: 185 KRGKKLVELPYTVKGMDVSFSGILSFIEDVAHRMLATGECTPEDLCFSLQETVFAMLVEI 244 Query: 236 TERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGL 295 TERA+AH E ++VGGV N RL+EM+ M ++RG + F C DNGAMIA G Sbjct: 245 TERAMAHCGSQEALIVGGVGCNVRLQEMMATMCQERGARLFATDERFCIDNGAMIAQAGW 304 Query: 296 RMYKAGISFRLEETIVKQKFRTDEVEIVW 324 M++AG L ++ V Q++RTDEVE+ W Sbjct: 305 EMFRAGHRTPLSDSGVTQRYRTDEVEVTW 333 >pir||T39567 glycoprotein endopeptidase-like protein - fission yeast (Schizosaccharomyces pombe) >gi|4481949|emb|CAB38507.1| (AL035637) glycoprotein endopeptidase-like protein. [Schizosaccharomyces pombe] Length = 346 Score = 303 bits (768), Expect = 2e-81 Identities = 162/340 (47%), Positives = 219/340 (63%), Gaps = 16/340 (4%) Query: 1 MLALGIEGTAHTLGIGIVSED-----KVLANVFDTLTTEKG-GIHPKEAAEHHARLMKPL 54 ++ALG+EG+A+ LG+GI+ D K+LANV T T G G P + A+HH + PL Sbjct: 5 LIALGLEGSANKLGVGIILHDTNGSAKILANVRHTYITPPGQGFLPSDTAKHHRAWIIPL 64 Query: 55 LRKALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEI 114 +++A +EA +S DID I F++GPG+G L VA AR L++ ++KP+V VNHCI H+E+ Sbjct: 65 IKQAFAEAKISFKDIDCICFTKGPGIGAPLNSVALCARMLSLIHKKPLVAVNHCIGHIEM 124 Query: 115 TK-MFGVKDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGP 173 + + G ++PV LYVSGGNTQV+A +YR+FGETLDI IGN +D FAR +GL P Sbjct: 125 GREITGAQNPVVLYVSGGNTQVIAYSEKKYRIFGETLDIAIGNCLDRFARIIGLSNAPSP 184 Query: 174 --KVEKLAEKGEKYIELPYAVKGMDLSFSGLL-------TEAIRKYRSGKYRVEDLAYSF 224 + + A+KG+++IELPY VKGMD SFSGLL TE + +DL YS Sbjct: 185 GYNIMQEAKKGKRFIELPYTVKGMDCSFSGLLSGVEAAATELLDPKNPSSVTKQDLCYSL 244 Query: 225 QETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCR 284 QET FA LVE+TERA+AH D V++VGGV N RL++M+ M+ DRG F C Sbjct: 245 QETGFAMLVEITERAMAHIRADSVLIVGGVGCNERLQQMMAEMSSDRGADVFSTDERFCI 304 Query: 285 DNGAMIAYTGLRMYKAGISFRLEETIVKQKFRTDEVEIVW 324 DNG MIA GL YK G + E+ + Q++RTD+V I W Sbjct: 305 DNGIMIAQAGLLAYKTGDRCAVAESTITQRYRTDDVYISW 344 >pir||H72714 probable O-sialoglycoprotein endopeptidase APE1135 - Aeropyrum pernix (strain K1) >gi|5104805|dbj|BAA80120.1| (AP000060) 349aa long hypothetical O-sialoglycoprotein endopeptidase [Aeropyrum pernix] Length = 349 Score = 290 bits (735), Expect = 1e-77 Identities = 161/331 (48%), Positives = 211/331 (63%), Gaps = 8/331 (2%) Query: 1 MLALGIEGTAHTLGIGIVSEDK--VLANVFDTLTTEKGGIHPKEAAEHHARLMKPLLRKA 58 +L LGIE TAHT G+GIVS V A+V T +GGI P+E AE + + +A Sbjct: 9 VLVLGIESTAHTFGVGIVSTRPPIVRADVRRRWTPREGGILPREVAEFFSLHAGEAVAEA 68 Query: 59 LSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKM- 117 L EAGVS+ D+D +A + GPG+GPALRV AT ARAL+ KY KP+V VNH +AHVE + Sbjct: 69 LGEAGVSIADVDAVAVALGPGMGPALRVGATVARALSAKYGKPLVPVNHAVAHVEAARFT 128 Query: 118 FGVKDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVFARELGLGFP----GGP 173 G++DPV LYV+GGNT V++ GRYR FGETLDI +GN +D FARE G+ P G Sbjct: 129 TGLRDPVALYVAGGNTTVVSFVAGRYRTFGETLDIALGNLLDTFAREAGIAPPYVAGGLH 188 Query: 174 KVEKLAEKGEKYIELPYAVKGMDLSFSGLLTEAIRKYRSGKYRVEDLAYSFQETAFAALV 233 V++ AE G +PY VKG D+SFSG+LT A+R + G R+ D+ Y+ +E AF+++V Sbjct: 189 AVDRCAEGGGFVEGIPYVVKGQDVSFSGILTAALRLLKRGA-RLSDVCYTLREVAFSSVV 247 Query: 234 EVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYT 293 EVTER +AHT K + L GGVAAN L E + +M G + L DNG MIA T Sbjct: 248 EVTERCLAHTGKRQATLTGGVAANRVLNEKMSLMAGLHGAVYRPVDVRLSGDNGVMIALT 307 Query: 294 GLRMYKAGISFRLEETIVKQKFRTDEVEIVW 324 GL Y G+ E ++Q++R DEV+I W Sbjct: 308 GLAAYLHGVIIDPGEAYIRQRWRIDEVDIPW 338 >dbj|BAA82123.1| (AB023065) O-sialoglycoprotease [Rattus norvegicus] Length = 322 Score = 283 bits (716), Expect = 2e-75 Identities = 148/318 (46%), Positives = 210/318 (65%), Gaps = 8/318 (2%) Query: 4 LGIEGTAHTLGIGIVSEDKVLANVFDTLTTEKG-GIHPKEAAEHHARLMKPLLRKALSEA 62 LG EG+A+ +G+G+V + VLAN T T G G P + A HH ++ LL++AL+EA Sbjct: 5 LGFEGSANKIGVGVVRDGTVLANPRRTYVTAPGTGFLPGDTARHHRAVILDLLQEALTEA 64 Query: 63 GVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKMF-GVK 121 G++ DID IA+++GPG+G L VA AR +A + KP++GVNHCI H+E+ ++ G Sbjct: 65 GLTPKDIDCIAYTKGPGMGAPLASVAVVARTVAQLWNKPLLGVNHCIGHIEMGRLITGAV 124 Query: 122 DPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGP--KVEKLA 179 +P LYVSGGNTQV++ RYR+FGET+DI +GN +D FAR L + P +E++A Sbjct: 125 NPTVLYVSGGNTQVISYSEHRYRIFGETIDIAVGNCLDRFARVLKISNDPSPGYNIEQMA 184 Query: 180 EKGEKYIELPYAVKGMDLSFSGLLT----EAIRKYRSGKYRVEDLAYSFQETAFAALVEV 235 ++G+K +ELPY VKGMD+SFSG+L+ A R +G+ EDL +S QET FA LVE+ Sbjct: 185 KRGKKLVELPYTVKGMDVSFSGILSFIEDAAQRMLATGECTPEDLCFSLQETVFAMLVEI 244 Query: 236 TERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGL 295 TERA+AH E ++VGGV N RL+EM+ M ++RG + F C DNGAMIA G Sbjct: 245 TERAMAHCGSKEALIVGGVGCNVRLQEMMATMCQERGAQLFATDERFCIDNGAMIAQAGW 304 Query: 296 RMYKAGISFRLEETIVKQ 313 M++AG L+++ + Q Sbjct: 305 EMFQAGHRTPLQDSGITQ 322 >gi|6322891 probable calcium-binding protein; Ykr038cp [Saccharomyces cerevisiae] >gi|549609|sp|P36132|YK18_YEAST HYPOTHETICAL 46.6 KDA PROTEIN IN DAL80-GAP1 INTERGENIC REGION >gi|539319|pir||S38110 O-sialoglycoprotein endopeptidase homolog YKR038c - yeast (Saccharomyces cerevisiae) >gi|486477|emb|CAA82112.1| (Z28263) ORF YKR038c [Saccharomyces cerevisiae] Length = 421 Score = 263 bits (665), Expect = 2e-69 Identities = 162/368 (44%), Positives = 215/368 (58%), Gaps = 45/368 (12%) Query: 2 LALGIEGTAHTLGIGIVS----------------EDKVLANVFDTLTTEKG-GIHPKEAA 44 +ALG+EG+A+ LG+GIV E ++L+N+ DT T G G P++ A Sbjct: 52 IALGLEGSANKLGVGIVKHPLLPKHANSDLSYDCEAEMLSNIRDTYVTPPGEGFLPRDTA 111 Query: 45 EHHARLMKPLLRKALSEAGVSLD--DIDVIAFSQGPGLGPALRVVATAARALAVKYRKPI 102 HH L+++AL+EA + DIDVI F++GPG+G L V AAR ++ + P+ Sbjct: 112 RHHRNWCIRLIKQALAEADIKSPTLDIDVICFTKGPGMGAPLHSVVIAARTCSLLWDVPL 171 Query: 103 VGVNHCIAHVEITK-MFGVKDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVF 161 VGVNHCI H+E+ + + ++PV LYVSGGNTQV+A RYR+FGETLDI IGN +D F Sbjct: 172 VGVNHCIGHIEMGREITKAQNPVVLYVSGGNTQVIAYSEKRYRIFGETLDIAIGNCLDRF 231 Query: 162 ARELGLGFPGGP--KVEKLAEKG---EKYIELPYAVKGMDLSFSGLLT----------EA 206 AR L + P +E+LA+K E +ELPY VKGMDLS SG+L + Sbjct: 232 ARTLKIPNEPSPGYNIEQLAKKAPHKENLVELPYTVKGMDLSMSGILASIDLLAKDLFKG 291 Query: 207 IRKYR--------SGKYRVEDLAYSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANN 258 +K + K VEDL YS QE FA LVE+TERA+AH ++V++VGGV N Sbjct: 292 NKKNKILFDKTTGEQKVTVEDLCYSLQENLFAMLVEITERAMAHVNSNQVLIVGGVGCNV 351 Query: 259 RLREMLRIMTEDRGI-KFFVPPYDLCRDNGAMIAYTGLRMYK-AGISFRLEETIVKQKFR 316 RL+EM+ M +DR + C DNG MIA GL Y+ GI ET+V QKFR Sbjct: 352 RLQEMMAQMCKDRANGQVHATDNRFCIDNGVMIAQAGLLEYRMGGIVKDFSETVVTQKFR 411 Query: 317 TDEVEIVW 324 TDEV W Sbjct: 412 TDEVYAAW 419 >gb|AAG20204.1| (AE005096) O-sialoglycoprotein endopeptidase homolog; Gcp [Halobacterium sp. NRC-1] Length = 483 Score = 244 bits (616), Expect = 1e-63 Identities = 133/263 (50%), Positives = 163/263 (61%), Gaps = 3/263 (1%) Query: 63 GVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITK-MFGVK 121 G + DID +AFS+GPGLGP LR+V +AARALA P+VGVNH +AH+EI + G + Sbjct: 14 GAADGDIDAVAFSRGPGLGPCLRIVGSAARALAQALDVPLVGVNHMVAHLEIGRHQSGFQ 73 Query: 122 DPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGPKVEKLAEK 181 PV L SG N VLA GRYRV GET+D G+GNAID F R +G PGGPKVE A Sbjct: 74 QPVCLNASGANAHVLAYRNGRYRVLGETMDTGVGNAIDKFTRHVGWQHPGGPKVETHARD 133 Query: 182 GEKYIELPYAVKGMDLSFSGLLTEAIRKYRSGKYRVEDLAYSFQETAFAALVEVTERAVA 241 GE Y LPY VKGMD SFSG+++ A G V D+ +ET FA L EV ERA+A Sbjct: 134 GE-YTALPYVVKGMDFSFSGIMSAAKDAVDDG-VPVADVCRGLEETMFAMLTEVAERALA 191 Query: 242 HTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGLRMYKAG 301 T +DE+VL GGV N+RLR ML M RG F P RDN MIA G +M AG Sbjct: 192 LTGRDELVLGGGVGQNDRLRGMLEAMCAARGASFHAPEPRFLRDNAGMIAVLGAKMAAAG 251 Query: 302 ISFRLEETIVKQKFRTDEVEIVW 324 + + ++ + +FR DEV + W Sbjct: 252 ATIPVADSAINSQFRPDEVSVTW 274 >gb|AAK40758.1| O-sialoglycoprotein endopeptidase [Sulfolobus solfataricus] Length = 246 Score = 215 bits (541), Expect = 7e-55 Identities = 115/246 (46%), Positives = 164/246 (65%), Gaps = 7/246 (2%) Query: 84 LRVVATAARALAVKYRKPIVGVNHCIAHVEITKMFG-VKDPVGLYVSGGNTQVLALEGGR 142 +RV AT ARA+A+KY K +V VNH I H+EI + +DP+ LY+SGGNT + GR Sbjct: 1 MRVGATLARAIALKYNKKLVPVNHGIGHIEIGYLTTEARDPLILYLSGGNTIITTFYKGR 60 Query: 143 YRVFGETLDIGIGNAIDVFARELGLGFP----GGPKVEKLAEKGEKYIELPYAVKGMDLS 198 +RVFGETLDI +GN +DVF RE+ L P G ++ AEKG K ++LPY VKG D+S Sbjct: 61 FRVFGETLDIALGNMMDVFVREVSLAPPYIINGIHVIDICAEKGNKLLKLPYVVKGQDMS 120 Query: 199 FSGLLTEAIRKYRSGKYRVEDLAYSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANN 258 FSGLLT A+R GK ++ED+ YS +E AF L+E TERA+A T K E+++VGGVAA+ Sbjct: 121 FSGLLTAALRVV--GKEKLEDICYSVREIAFDMLLEATERALALTSKKELMIVGGVAASV 178 Query: 259 RLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGLRMYKAGISFRLEETIVKQKFRTD 318 LR+ L + ++ ++ + P + DNGAMIAY G+ G+ ++++ ++ ++R D Sbjct: 179 SLRKKLEELGKEWNVQIKIVPPEFAGDNGAMIAYAGMLAASKGVFIDVDKSYIRPRWRVD 238 Query: 319 EVEIVW 324 EV+I W Sbjct: 239 EVDIPW 244 >sp|P43764|GCP_HAEIN PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROTEASE) >gi|1075307|pir||H64074 O-sialoglycoprotein endopeptidase (EC 3.4.24.57) - Haemophilus influenzae (strain Rd KW20) >gi|1573514|gb|AAC22187.1| (U32735) O-sialoglycoprotein endopeptidase (gcp) [Haemophilus influenzae Rd] Length = 342 Score = 192 bits (482), Expect = 6e-48 Identities = 125/322 (38%), Positives = 174/322 (53%), Gaps = 22/322 (6%) Query: 1 MLALGIEGTAHTLGIGIVSEDK-VLANVFDT---LTTEKGGIHPKEAAEHHARLMKPLLR 56 M LGIE + G+ I E+K ++AN T L + GG+ P+ A+ H R PL++ Sbjct: 1 MKILGIETSCDETGVAIYDEEKGLIANQLYTQIALHADYGGVVPELASRDHIRKTAPLIK 60 Query: 57 KALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITK 116 AL EA ++ DID IA++ GPGL AL V AT AR+LA + P +GV+H H+ + Sbjct: 61 AALEEANLTASDIDGIAYTSGPGLVGALLVGATIARSLAYAWNVPAIGVHHMEGHL-LAP 119 Query: 117 MFGVKDP----VGLYVSGGNTQVLALEG-GRYRVFGETLDIGIGNAIDVFARELGLGFPG 171 M P V L VSGG+TQ++ ++G G+Y V GE++D G A D A+ LGL +PG Sbjct: 120 MLDDNSPHFPFVALLVSGGHTQLVRVDGVGKYEVIGESIDDAAGEAFDKTAKLLGLDYPG 179 Query: 172 GPKVEKLAEKG-EKYIELPYAV---KGMDLSFSGLLTEAIRKYRSG--------KYRVED 219 G + +LAEKG P + G+D SFSGL T A + D Sbjct: 180 GAALSRLAEKGTPNRFTFPRPMTDRAGLDFSFSGLKTFAANTVNQAIKNEGELIEQTKAD 239 Query: 220 LAYSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPP 279 +AY+FQ+ L +RA+ T +V+ GGV+AN +LRE L + ++ G + F P Sbjct: 240 IAYAFQDAVVDTLAIKCKRALKETGYKRLVIAGGVSANKKLRETLAHLMQNLGGEVFYPQ 299 Query: 280 YDLCRDNGAMIAYTGLRMYKAG 301 C DNGAMIAYTG K G Sbjct: 300 PQFCTDNGAMIAYTGFLRLKQG 321 >sp|P36174|YHSH_HALMA HYPOTHETICAL PROTEIN IN HSH 3'REGION (ORFX) >gi|282647|pir||S27037 hypothetical protein X - Haloarcula marismortui >gi|312781|emb|CAA49709.1| (X70117) HmaORFx [Haloarcula marismortui] Length = 226 Score = 190 bits (479), Expect = 1e-47 Identities = 106/222 (47%), Positives = 136/222 (60%), Gaps = 17/222 (7%) Query: 1 MLALGIEGTAHTLGIGI--------VSEDKVLANVFDTLTTEKGGIHPKEAAEHHARLMK 52 M LGIEGTA + V++D + D + GGIHP+EAAEH + Sbjct: 1 MRILGIEGTAWAASASVFETPDPARVTDDDHVFIETDAYAPDSGGIHPREAAEHMGEAIP 60 Query: 53 PLLRKALSE----AGVSLDD---IDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGV 105 ++ A+ AG DD ID +AF++GPGLGP LR+VATAARA+A ++ P+VGV Sbjct: 61 TVVETAIEHTHGRAGRDGDDSAPIDAVAFARGPGLGPCLRIVATAARAVAQRFDVPLVGV 120 Query: 106 NHCIAHVEITK-MFGVKDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVFARE 164 NH +AH+E+ + G PV L SG N +L GRYRV GET+D G+GNAID F R Sbjct: 121 NHMVAHLEVGRHRSGFDSPVCLNASGANAHILGYRNGRYRVLGETMDTGVGNAIDKFTRH 180 Query: 165 LGLGFPGGPKVEKLAEKGEKYIELPYAVKGMDLSFSGLLTEA 206 +G PGGPKVE+ A GE Y ELPY VKGMD SFSG+++ A Sbjct: 181 IGWSHPGGPKVEQHARDGE-YHELPYVVKGMDFSFSGIMSAA 221 >sp|O66986|GCP_AQUAE PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROTEASE) >gi|7444713|pir||G70369 sialoglycoproteinase - Aquifex aeolicus >gi|2983364|gb|AAC06951.1| (AE000708) sialoglycoprotease [Aquifex aeolicus] Length = 335 Score = 190 bits (477), Expect = 2e-47 Identities = 117/313 (37%), Positives = 182/313 (57%), Gaps = 11/313 (3%) Query: 1 MLALGIEGTAHTLGIGIVSEDK-VLANVF---DTLTTEKGGIHPKEAAEHHARLMKPLLR 56 M L +E + + I + K VL NV + + GG+ P+ +A H R + P+ Sbjct: 1 MRTLAVETSCDETALAIYDDQKGVLGNVILSQAVVHSPFGGVVPELSAREHTRNILPIFD 60 Query: 57 KALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHV-EIT 115 + L E+ ++L++ID I+F+ PGL +L V A+ALA +YRKP+V V+H H+ + Sbjct: 61 RLLKESRINLEEIDFISFTLTPGLILSLVVGVAFAKALAYEYRKPLVPVHHLEGHIYSVF 120 Query: 116 KMFGVKDP-VGLYVSGGNTQV-LALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGP 173 V+ P + L +SGG+T + L + GRY G TLD +G A D A+ LGLG+PGGP Sbjct: 121 LEKKVEYPFLALIISGGHTDLYLVRDFGRYDFLGGTLDDAVGEAYDKVAKMLGLGYPGGP 180 Query: 174 KVEKLAEKGEKYIELPYAVK---GMDLSFSGLLTEAIRKYRSGK-YRVEDLAYSFQETAF 229 +++LA++G+K LP + ++ SFSGL T + + K R ED+AYSFQET Sbjct: 181 IIDRLAKEGKKLYPLPKPLMEEGNLNFSFSGLKTAILNLLKKEKNVRKEDIAYSFQETVV 240 Query: 230 AALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAM 289 L+E + A+ T +V+VGGV+AN+RLRE+ + +++ G + ++P L DN M Sbjct: 241 EILLEKSLWAMKKTGIKRLVVVGGVSANSRLREVFKKASQEYGFELYIPHPSLSTDNALM 300 Query: 290 IAYTGLRMYKAGI 302 IAY G+ +K G+ Sbjct: 301 IAYAGMERFKRGV 313 >sp|O05518|GCP_BACSU PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROTEASE) >gi|7444711|pir||F69786 glycoprotein endopeptidase homolog ydiE - Bacillus subtilis >gi|1945110|dbj|BAA19718.1| (D88802) P. haemolytica o-sialoglycoprotein endopeptidase; P36175 (660) transmembrane [Bacillus subtilis] >gi|2632907|emb|CAB12413.1| (Z99107) similar to glycoprotein endopeptidase [Bacillus subtilis] Length = 346 Score = 188 bits (473), Expect = 7e-47 Identities = 121/318 (38%), Positives = 174/318 (54%), Gaps = 16/318 (5%) Query: 1 MLALGIEGTAHTLGIGIVSEDK-VLANVFDT-LTTEK--GGIHPKEAAEHHARLMKPLLR 56 M LGIE + IV K +++NV + + + K GG+ P+ A+ HH + ++ Sbjct: 7 MYVLGIETSCDETAAAIVKNGKEIISNVVASQIESHKRFGGVVPEIASRHHVEQITLVIE 66 Query: 57 KALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITK 116 +A +AG++ DID IA ++GPGL AL + AA+AL+ Y P+VGV+H H+ + Sbjct: 67 EAFRKAGMTYSDIDAIAVTEGPGLVGALLIGVNAAKALSFAYNIPLVGVHHIAGHIYANR 126 Query: 117 MFG--VKDPVGLYVSGGNTQVLAL-EGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGP 173 + V + L VSGG+T+++ + E G + V GETLD G A D AR +GL +PGGP Sbjct: 127 LVEDIVFPALALVVSGGHTELVYMKEHGSFEVIGETLDDAAGEAYDKVARTMGLPYPGGP 186 Query: 174 KVEKLAEKGEKYIELPYA---VKGMDLSFSGLLTEAIRKYRSGKYR-----VEDLAYSFQ 225 +++KLAEKG I LP A + SFSGL + I + + EDL+ SFQ Sbjct: 187 QIDKLAEKGNDNIPLPRAWLEEGSYNFSFSGLKSAVINTLHNASQKGQEIAPEDLSASFQ 246 Query: 226 ETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREML-RIMTEDRGIKFFVPPYDLCR 284 + LV T RA + +V+L GGVAAN LR L + + GI +PP LC Sbjct: 247 NSVIDVLVTKTARAAKEYDVKQVLLAGGVAANRGLRAALEKEFAQHEGITLVIPPLALCT 306 Query: 285 DNGAMIAYTGLRMYKAGI 302 DN AMIA G ++ GI Sbjct: 307 DNAAMIAAAGTIAFEKGI 324 >pir||G72411 hypothetical protein TM0145 - Thermotoga maritima (strain MSB8) >gi|4980638|gb|AAD35238.1|AE001700_2 (AE001700) secreted metalloendopeptidase Gcp, putative [Thermotoga maritima] Length = 327 Score = 182 bits (457), Expect = 5e-45 Identities = 125/316 (39%), Positives = 173/316 (54%), Gaps = 17/316 (5%) Query: 1 MLALGIEGTAHTLGIGIVSEDKVLANVFDTLTTEK----GGIHPKEAAEHHARLMKPLLR 56 M LGIE + + ++ + K + F E GG+ P+ AA HH + + LL+ Sbjct: 1 MRVLGIETSCDETAVAVLDDGKNVVVNFTVSQIEVHQKFGGVVPEVAARHHLKNLPILLK 60 Query: 57 KALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITK 116 KA + V + +DV+A + GPGL AL V +AA+ LA+ KP VGVNH AHV+ Sbjct: 61 KAFEK--VPPETVDVVAATYGPGLIGALLVGLSAAKGLAISLEKPFVGVNHVEAHVQAVF 118 Query: 117 MFG--VKDP-VGLYVSGGNTQVLAL-EGGRYRVFGETLDIGIGNAIDVFARELGLGFPGG 172 + +K P V L VSGG+TQ++ + E V GETLD G A D AR LGLG+PGG Sbjct: 119 LANPDLKPPLVVLMVSGGHTQLMKVDEDYSMEVLGETLDDSAGEAFDKVARLLGLGYPGG 178 Query: 173 PKVEKLAEKG--EKYIELPYAVKGMD---LSFSGLLTEAIRKYRSGK-YRVEDLAYSFQE 226 P ++++A+KG EKY P + D SF+GL T + + K Y+VED+A SFQ+ Sbjct: 179 PVIDRVAKKGDPEKY-SFPRPMLDDDSYNFSFAGLKTSVLYFLQREKGYKVEDVAASFQK 237 Query: 227 TAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDN 286 LVE T R + ++ VGGVAAN+ LRE +R E + F PP +LC DN Sbjct: 238 AVVDILVEKTFRLARNLGIRKIAFVGGVAANSMLREEVRKRAERWNYEVFFPPLELCTDN 297 Query: 287 GAMIAYTGLRMYKAGI 302 M+A G K G+ Sbjct: 298 ALMVAKAGYEKAKRGM 313 >pir||QQECR6 O-sialoglycoprotein endopeptidase (EC 3.4.24.57) - Escherichia coli >gi|882587|gb|AAA89144.1| (U28379) ORF_f337 [Escherichia coli] >gi|1789445|gb|AAC76100.1| (AE000388) putative O-sialoglycoprotein endopeptidase [Escherichia coli K12] Length = 337 Score = 177 bits (445), Expect = 1e-43 Identities = 120/318 (37%), Positives = 178/318 (55%), Gaps = 19/318 (5%) Query: 1 MLALGIEGTAHTLGIGIVSEDK-VLANVFDT---LTTEKGGIHPKEAAEHHARLMKPLLR 56 M LGIE + GI I ++K +LAN + L + GG+ P+ A+ H R PL++ Sbjct: 1 MRVLGIETSCDETGIAIYDDEKGLLANQLYSQVKLHADYGGVVPELASRDHVRKTVPLIQ 60 Query: 57 KALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITK 116 AL E+G++ DID +A++ GPGL AL V AT R+LA + P + V+H H+ + Sbjct: 61 AALKESGLTAKDIDAVAYTAGPGLVGALLVGATVGRSLAFAWDVPAIPVHHMEGHL-LAP 119 Query: 117 MFGVKDP----VGLYVSGGNTQVLALEG-GRYRVFGETLDIGIGNAIDVFARELGLGFPG 171 M P V L VSGG+TQ++++ G G+Y + GE++D G A D A+ LGL +PG Sbjct: 120 MLEDNPPEFPFVALLVSGGHTQLISVTGIGQYELLGESIDDAAGEAFDKTAKLLGLDYPG 179 Query: 172 GPKVEKLAEKGEK---YIELPYAVK-GMDLSFSGLLTEA---IRKYRSGKYRVEDLAYSF 224 GP + K+A +G P + G+D SFSGL T A IR + D+A +F Sbjct: 180 GPLLSKMAAQGTAGRFVFPRPMTDRPGLDFSFSGLKTFAANTIRDNGTDDQTRADIARAF 239 Query: 225 QETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLR-EMLRIMTEDRGIKFFVPPYDLC 283 ++ L+ +RA+ T +V+ GGV+AN LR ++ +M + RG F+ P + C Sbjct: 240 EDAVVDTLMIKCKRALDQTGFKRLVMAGGVSANRTLRAKLAEMMKKRRGEVFYARP-EFC 298 Query: 284 RDNGAMIAYTGLRMYKAG 301 DNGAMIAY G+ +KAG Sbjct: 299 TDNGAMIAYAGMVRFKAG 316 >sp|P05852|GCP_ECOLI PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROTEASE) >gi|551834|gb|AAA72575.1| (M16194) [Escherichia coli rpsU gene encoding ribosomal protein S21, partial cds, with 5' flank encoding three unidentified proteins, complete cds..], gene products >gi|225555|prf||1306285D ORF x,upsU upstream [Escherichia coli] Length = 337 Score = 175 bits (440), Expect = 5e-43 Identities = 119/318 (37%), Positives = 177/318 (55%), Gaps = 19/318 (5%) Query: 1 MLALGIEGTAHTLGIGIVSEDK-VLANVFDT---LTTEKGGIHPKEAAEHHARLMKPLLR 56 M LGIE + GI I ++K +LAN + L + GG+ P+ A+ H R PL++ Sbjct: 1 MRVLGIETSCDETGIAIYDDEKGLLANQLYSQVKLHADYGGVVPELASRDHVRKTVPLIQ 60 Query: 57 KALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITK 116 AL E+G++ DID +A++ GPGL AL V AT R+LA + P + V+H H+ + Sbjct: 61 AALKESGLTAKDIDAVAYTAGPGLVGALLVGATVGRSLAFAWDVPAIPVHHMEGHL-LAP 119 Query: 117 MFGVKDP----VGLYVSGGNTQVLALEG-GRYRVFGETLDIGIGNAIDVFARELGLGFPG 171 M P V L V GG+TQ++++ G G+Y + GE++D G A D A+ LGL +PG Sbjct: 120 MLEDNPPEFPFVALLVCGGHTQLISVTGIGQYELLGESIDDAAGEAFDKTAKLLGLDYPG 179 Query: 172 GPKVEKLAEKGEK---YIELPYAVK-GMDLSFSGLLTEA---IRKYRSGKYRVEDLAYSF 224 GP + K+A +G P + G+D SFSGL T A IR + D+A +F Sbjct: 180 GPLLSKMAAQGTAGRFVFPRPMTDRPGLDFSFSGLKTFAANTIRDNGTDDQTRADIARAF 239 Query: 225 QETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLR-EMLRIMTEDRGIKFFVPPYDLC 283 ++ L+ +RA+ T +V+ GGV+AN LR ++ +M + RG F+ P + C Sbjct: 240 EDAVVDTLMIKCKRALDQTGFKRLVMAGGVSANRTLRAKLAEMMKKRRGEVFYARP-EFC 298 Query: 284 RDNGAMIAYTGLRMYKAG 301 DNGAMIAY G+ +KAG Sbjct: 299 TDNGAMIAYAGMVRFKAG 316 >sp|O86793|GCP_STRCO PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROTEASE) >gi|7481089|pir||T35581 probable O-sialoglycoprotein endopeptidase - Streptomyces coelicolor >gi|3449264|emb|CAA20408.1| (AL031317) putative O-sialoglycoprotein endopeptidase [Streptomyces coelicolor A3(2)] Length = 374 Score = 175 bits (440), Expect = 5e-43 Identities = 120/315 (38%), Positives = 166/315 (52%), Gaps = 19/315 (6%) Query: 2 LALGIEGTAHTLGIGIVSEDKVLANVFDTLTTEK---GGIHPKEAAEHHARLMKPLLRKA 58 L LGIE + G+G+V +LA+ + E GG+ P+ A+ H M P + +A Sbjct: 9 LVLGIETSCDETGVGVVRGTTLLADAVASSVDEHARFGGVVPEVASRAHLEAMVPTIDRA 68 Query: 59 LSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKM- 117 L EAGVS D+D IA + GPGL AL V +AA+A A KP+ GVNH +H+ + ++ Sbjct: 69 LKEAGVSARDLDGIAVTAGPGLAGALLVGVSAAKAYAYALGKPLYGVNHLASHICVDQLE 128 Query: 118 -FGVKDP-VGLYVSGGNTQVLALEG--GRYRVFGETLDIGIGNAIDVFARELGLGFPGGP 173 + +P + L VSGG++ +L R G T+D G A D AR L LGFPGGP Sbjct: 129 HGALPEPTMALLVSGGHSSLLLSTDITSDVRPLGATIDDAAGEAFDKIARVLNLGFPGGP 188 Query: 174 KVEKLAEKGE-KYIELPYAVKG-----MDLSFSGLLTEAIR----KYRSG-KYRVEDLAY 222 +++ A +G+ I P + G D SFSGL T R K +G + V D++ Sbjct: 189 VIDRYAREGDPNAIAFPRGLTGPRDAAYDFSFSGLKTAVARWIEAKRAAGEEVPVRDVSA 248 Query: 223 SFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDL 282 SFQE L RA D +++ GGVAAN+RLR + + E GI+ VP L Sbjct: 249 SFQEAVVDVLTRKAVRACKDEGVDHLMIGGGVAANSRLRALAQERCEAAGIRLRVPRPKL 308 Query: 283 CRDNGAMIAYTGLRM 297 C DNGAM+A G M Sbjct: 309 CTDNGAMVAALGAEM 323 >pir||H83572 O-sialoglycoprotein endopeptidase PA0580 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9946451|gb|AAG03969.1|AE004494_5 (AE004494) O-sialoglycoprotein endopeptidase [Pseudomonas aeruginosa] Length = 341 Score = 173 bits (435), Expect = 2e-42 Identities = 118/322 (36%), Positives = 180/322 (55%), Gaps = 23/322 (7%) Query: 1 MLALGIEGTAHTLGIGIV-SEDKVLAN-VFDTLTTEK--GGIHPKEAAEHHARLMKPLLR 56 M LG+E + G+ + SE +LA+ +F + + GG+ P+ A+ H + M PL+R Sbjct: 1 MRVLGLETSCDETGVALYDSERGLLADALFSQIDLHRVYGGVVPELASRDHVKRMLPLIR 60 Query: 57 KALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITK 116 + L E+G + DID IA++ GPGL AL V A+ A+A+A + P VGV+H H+ + Sbjct: 61 QVLDESGCTPADIDAIAYTAGPGLVGALLVGASCAQAMAFAWGVPAVGVHHMEGHL-LAP 119 Query: 117 MFGVKDP----VGLYVSGGNTQVLALEG-GRYRVFGETLDIGIGNAIDVFARELGLGFPG 171 M + P V L VSGG+TQ++ ++G GRY++ GE++D G A D A+ +GLG+PG Sbjct: 120 MLEEQPPRFPFVALLVSGGHTQLVRVDGIGRYQLLGESVDDAAGEAFDKTAKLIGLGYPG 179 Query: 172 GPKVEKLAEKGEK---YIELPYAVK-GMDLSFSGLLTEAIRKYR-------SGKYRVEDL 220 GP++ +LAE+G P + G+D SFSGL T + ++ + D+ Sbjct: 180 GPEIARLAERGTPGRFVFPRPMTDRPGLDFSFSGLKTFTLNTWQRCVEAGDDSEQTRCDI 239 Query: 221 AYSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREML-RIMTEDRGIKFFVPP 279 A +FQ L+ RA+ T +V+ GGV+AN LR L +++ E +G F+ P Sbjct: 240 ALAFQTAVVETLLIKCRRALKQTGLKNLVIAGGVSANQALRSGLEKMLGEMKGQVFYARP 299 Query: 280 YDLCRDNGAMIAYTGLRMYKAG 301 C DNGAMIAY G + AG Sbjct: 300 -RFCTDNGAMIAYAGCQRLLAG 320 >dbj|BAB04267.1| (AP001508) glycoprotein endopeptidase [Bacillus halodurans] Length = 343 Score = 173 bits (435), Expect = 2e-42 Identities = 107/304 (35%), Positives = 163/304 (53%), Gaps = 15/304 (4%) Query: 2 LALGIEGTAHTLGIGIVSEDK-VLANVFDT-LTTEK--GGIHPKEAAEHHARLMKPLLRK 57 L L IE + ++ +L+NV + + + K GG+ P+ A+ HH + ++ + Sbjct: 11 LILAIETSCDETSAAVIENGTTILSNVVSSQIDSHKRFGGVVPEIASRHHVEQITVIVEE 70 Query: 58 ALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKM 117 A+ EAGV D+ +A ++GPGL AL + AA+A+A ++ P++GV+H H+ ++ Sbjct: 71 AMHEAGVDFADLAAVAVTEGPGLVGALLIGVNAAKAIAFAHQLPLIGVHHIAGHIYANRL 130 Query: 118 FGVKD--PVGLYVSGGNTQVLALEG-GRYRVFGETLDIGIGNAIDVFARELGLGFPGGPK 174 + + L VSGG+T+++ +E G + V GET D +G A D AR LGL +PGGP Sbjct: 131 LKELEFPLLALVVSGGHTELIYMENHGEFEVIGETRDDAVGEAYDKVARTLGLPYPGGPH 190 Query: 175 VEKLAEKGEKYIELPYA---VKGMDLSFSGLLTEAIRKYRSGKYR-----VEDLAYSFQE 226 +++LA GE ++ P A D SFSGL + I + K R ED+A SFQ Sbjct: 191 IDRLAVNGEDTLQFPRAWLEPDSFDFSFSGLKSAVINTLHNAKQRGENVQAEDVAASFQA 250 Query: 227 TAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDN 286 + LV T++A + +V+L GGVAAN LR L I +PP LC DN Sbjct: 251 SVIDVLVTKTKKAAEEYKVRQVLLAGGVAANKGLRTALEEAFFKEPIDLVIPPLSLCTDN 310 Query: 287 GAMI 290 AMI Sbjct: 311 AAMI 314 >pir||D82807 O-sialoglycoprotein endopeptidase XF0435 [imported] - Xylella fastidiosa (strain 9a5c) >gi|9105277|gb|AAF83245.1|AE003894_10 (AE003894) O-sialoglycoprotein endopeptidase [Xylella fastidiosa] Length = 348 Score = 172 bits (432), Expect = 4e-42 Identities = 121/328 (36%), Positives = 176/328 (52%), Gaps = 35/328 (10%) Query: 1 MLALGIEGTAHTLGIGIVSEDKVLA--------NVFD--TLTTEKGGIHPKEAAEHHARL 50 M +GIE + G+ + D L+ +V+ L E GG+ P+ A+ H R Sbjct: 1 MKIIGIESSCDETGVAVY--DTALSGFAALRAHSVYSQVALHAEYGGVVPELASRDHVRK 58 Query: 51 MKPLLRKALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIA 110 + PLLR+ L+EA +S++++D +A++ GPGL AL V A ARALA P +GV+H Sbjct: 59 LLPLLRQTLAEAKLSVEELDGVAYTAGPGLVGALLVGAGVARALAWALEVPAIGVHHMEG 118 Query: 111 HVEITKMFGVKDP----VGLYVSGGNTQVLALEG-GRYRVFGETLDIGIGNAIDVFAREL 165 H+ ++ + P V L VSGG+TQ++A++ G YR+ GETLD G A D A+ + Sbjct: 119 HL-LSPLLEDDPPEVPFVALLVSGGHTQLVAVDAIGDYRLLGETLDDAAGEAFDKVAKLM 177 Query: 166 GLGFPGGPKVEKLAEKG--------EKYIELPYAVKGMDLSFSGLLTEAIRKYR----SG 213 GL +PGGP++ LAE+G ++ P G+D SFSGL T+ + +R S Sbjct: 178 GLPYPGGPQLAALAEQGIPGRFCFTRPMVDRP----GLDFSFSGLKTQVLLAWRNSDQSD 233 Query: 214 KYRVEDLAYSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGI 273 RV D+A F++ L ERA+ +V+ GGV AN LR L+ M RG Sbjct: 234 AIRV-DVARGFEDAVVDTLAIKCERALDTVACQTLVVAGGVGANKCLRARLQAMCRQRGG 292 Query: 274 KFFVPPYDLCRDNGAMIAYTGLRMYKAG 301 + P LC DNGAMIA+ G +AG Sbjct: 293 RACFPRPALCTDNGAMIAFAGALRLQAG 320 >pir||C81986 probable O-sialoglycoprotein endopeptidase (EC 3.4.24.57) NMA0661 [imported] - Neisseria meningitidis (group A strain Z2491) >gi|7379390|emb|CAB83948.1| (AL162753) putative O-sialoglycoprotein endopeptidase [Neisseria meningitidis Z2491] Length = 354 Score = 169 bits (424), Expect = 4e-41 Identities = 118/329 (35%), Positives = 171/329 (51%), Gaps = 36/329 (10%) Query: 1 MLALGIEGTAHTLGIGIVSEDKVL-ANVFDT---LTTEKGGIHPKEAAEHHARLMKPLLR 56 ML LGIE + G+ + ++ L A+ T + E GG+ P+ A+ H R + PL Sbjct: 1 MLVLGIESSCDETGVALYDTERGLRAHCLHTQMAMHAEYGGVVPELASRDHIRRLVPLTE 60 Query: 57 KALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITK 116 L++AG S DID +AF+QGPGLG AL ++ A ALA+ KP++ V+H H+ ++ Sbjct: 61 GCLAQAGASYGDIDAVAFTQGPGLGGALLAGSSYANALALALDKPVIPVHHLEGHL-LSP 119 Query: 117 MFGVKDP----VGLYVSGGNTQVLALEG-GRYRVFGETLDIGIGNAIDVFARELGLGFPG 171 + + P V L VSGG+TQ++A+ G G Y + GE++D G A D A+ LGL +PG Sbjct: 120 LLAEEKPDFPFVALLVSGGHTQIMAVRGIGDYALLGESVDDAAGEAFDKTAKLLGLPYPG 179 Query: 172 GPKVEKLAEKG--EKYIELPYAVKGMDL--SFSGLLT---EAIRKYRS-------GKYRV 217 G K+ +LAE G E ++ + DL SFSGL T A+ K R+ + Sbjct: 180 GAKLSELAESGRPEAFVFPRPMIHSDDLQMSFSGLKTAVLTAVEKVRAENGADDIPEQTR 239 Query: 218 EDLAYSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMT--------- 268 D+ +FQ+ L ++A+ T VV+ GGV AN +LRE MT Sbjct: 240 NDICRAFQDAVVDVLAAKVKKALLQTGFRTVVVAGGVGANRKLRETFGNMTVQIPTPKGK 299 Query: 269 ---EDRGIKFFVPPYDLCRDNGAMIAYTG 294 + F PP C DNGAMIA+ G Sbjct: 300 PKHPSEKVSVFFPPTAYCTDNGAMIAFAG 328 >sp|P36175|GCP_PASHA O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROTEASE) >gi|97190|pir||A38108 O-sialoglycoprotein endopeptidase (EC 3.4.24.57) [validated] - Pasteurella haemolytica (serotype A1) >gi|561690|gb|AAA80282.1| (U15958) sialoglycoprotease [Pasteurella haemolytica] Length = 325 Score = 169 bits (423), Expect = 5e-41 Identities = 115/320 (35%), Positives = 170/320 (52%), Gaps = 22/320 (6%) Query: 1 MLALGIEGTAHTLGIGIVSEDK-VLANVFDT---LTTEKGGIHPKEAAEHHARLMKPLLR 56 M LGIE + G+ I EDK ++AN + + + GG+ P+ A+ H R PL++ Sbjct: 1 MRILGIETSCDETGVAIYDEDKGLVANQLYSQIDMHADYGGVVPELASRDHIRKTLPLIQ 60 Query: 57 KALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITK 116 +AL EA + DID IA++ GPGL AL V +T AR+LA + P +GV+H H+ + Sbjct: 61 EALKEANLQPSDIDGIAYTAGPGLVGALLVGSTIARSLAYAWNVPALGVHHMEGHL-LAP 119 Query: 117 MFGVKDP----VGLYVSGGNTQVLALEG-GRYRVFGETLDIGIGNAIDVFARELGLGFPG 171 M P V L +SGG+TQ++ ++G G+Y + GE++D G A D + LGL +P Sbjct: 120 MLEENAPEFPFVALLISGGHTQLVKVDGVGQYELLGESIDDAAGEAFDKTGKLLGLDYPA 179 Query: 172 GPKVEKLAEKGE----KYIELPYAVKGMDLSFSGLLTEAIRKYRSG--------KYRVED 219 G + KLAE G K+ G+D SFSGL T A ++ + D Sbjct: 180 GVAMSKLAESGTPNRFKFPRPMTDRPGLDFSFSGLKTFAANTIKANLNENGELDEQTKCD 239 Query: 220 LAYSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPP 279 +A++FQ+ ++ +RA+ T +V+ GGV+AN +LR L M + + F P Sbjct: 240 IAHAFQQAVVDTILIKCKRALEQTGYKRLVMAGGVSANKQLRADLAEMMKKLKGEVFYPR 299 Query: 280 YDLCRDNGAMIAYTGLRMYK 299 C DNGAMIAYTG K Sbjct: 300 PQFCTDNGAMIAYTGFLRLK 319 >pir||C81040 O-sialoglycoprotein endopeptidase NMB1802 [imported] - Neisseria meningitidis (group B strain MD58) >gi|7227056|gb|AAF42139.1| (AE002530) O-sialoglycoprotein endopeptidase [Neisseria meningitidis MC58] Length = 354 Score = 168 bits (422), Expect = 6e-41 Identities = 118/329 (35%), Positives = 171/329 (51%), Gaps = 36/329 (10%) Query: 1 MLALGIEGTAHTLGIGIVSEDKVL-ANVFDT---LTTEKGGIHPKEAAEHHARLMKPLLR 56 ML LGIE + G+ + ++ L A+ T + E GG+ P+ A+ H R + PL Sbjct: 1 MLVLGIESSCDETGVALYDTERGLRAHCLHTQMAMHAEYGGVVPELASRDHIRRLVPLTE 60 Query: 57 KALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITK 116 L++AG S DID +AF+QGPGLG AL ++ A ALA+ KP++ V+H H+ ++ Sbjct: 61 GCLAQAGASYGDIDAVAFTQGPGLGGALLAGSSYANALALALDKPVIPVHHLEGHL-LSP 119 Query: 117 MFGVKDP----VGLYVSGGNTQVLALEG-GRYRVFGETLDIGIGNAIDVFARELGLGFPG 171 + + P V L VSGG+TQ++A+ G G Y + GE++D G A D A+ LGL +PG Sbjct: 120 LLAEEKPDFPFVALLVSGGHTQIMAVRGIGDYALLGESVDDAAGEAFDKTAKLLGLLYPG 179 Query: 172 GPKVEKLAEKG--EKYIELPYAVKGMDL--SFSGLLT---EAIRKYRS-------GKYRV 217 G K+ +LAE G E ++ + DL SFSGL T A+ K R+ + Sbjct: 180 GAKLSELAESGRFEAFVFPRPMIHSDDLQMSFSGLKTAVLTAVEKVRAENGADDIPEQTR 239 Query: 218 EDLAYSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMT--------- 268 D+ +FQ+ L ++A+ T VV+ GGV AN +LRE MT Sbjct: 240 NDICRAFQDAVVDVLAAKVKKALLQTGFRTVVVAGGVGANRKLRETFGNMTVQIPTPKGK 299 Query: 269 ---EDRGIKFFVPPYDLCRDNGAMIAYTG 294 + F PP C DNGAMIA+ G Sbjct: 300 PKHPSEKVSVFFPPTAYCTDNGAMIAFAG 328 >gb|AAF32396.1|AF224466_3 (AF224466) sialylglycoprotease [Haemophilus ducreyi] Length = 348 Score = 166 bits (415), Expect = 4e-40 Identities = 113/322 (35%), Positives = 169/322 (52%), Gaps = 22/322 (6%) Query: 1 MLALGIEGTAHTLGIGIVSEDK-VLANVFDT---LTTEKGGIHPKEAAEHHARLMKPLLR 56 M LGIE + G+ I E + ++AN + + + GG+ P+ A+ H R PL++ Sbjct: 1 MRILGIETSCDETGVAIYDEQRGLIANQLYSQIEMHADYGGVVPELASRDHIRKTLPLIQ 60 Query: 57 KALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITK 116 AL EA ++ +ID IA++ GPGL AL V AT ARALA + P + V+H H+ + Sbjct: 61 AALKEANLTASEIDGIAYTAGPGLVGALLVGATIARALAYAWNVPALAVHHMEGHL-MAP 119 Query: 117 MFGVKDP----VGLYVSGGNTQVLALEG-GRYRVFGETLDIGIGNAIDVFARELGLGFPG 171 M P + L +SGG+TQ++ + G G Y + GE++D G A D + LGL +P Sbjct: 120 MLEENPPEFPFIALLISGGHTQLIKVAGVGEYEILGESIDDAAGEAFDKTGKLLGLDYPA 179 Query: 172 GPKVEKLAEKG-EKYIELPYAV---KGMDLSFSGLLTEAIRKY-----RSGKYRVE---D 219 G + +LAEKG P + G+D SFSGL T A +G+ + D Sbjct: 180 GVALSQLAEKGTPNRFVFPRPMTDRPGLDFSFSGLKTFAANTINAQLDENGQLNEQTRCD 239 Query: 220 LAYSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPP 279 +A++FQ+ ++ +RA+ T +V+ GGV+AN +LR L M + + + P Sbjct: 240 IAHAFQQAVVDTIIIKCKRALQQTGYSRLVMAGGVSANKQLRAELATMMQALKGQVYYPR 299 Query: 280 YDLCRDNGAMIAYTGLRMYKAG 301 C DNGAMIAYTG K G Sbjct: 300 PQFCTDNGAMIAYTGFIRLKKG 321 >sp|P74034|GCP_SYNY3 PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROTEASE) >gi|7444708|pir||S75548 sialoglycoproteinase - Synechocystis sp. (strain PCC 6803) >gi|1653193|dbj|BAA18109.1| (D90911) sialoglycoprotease [Synechocystis sp.] Length = 348 Score = 164 bits (411), Expect = 1e-39 Identities = 113/321 (35%), Positives = 170/321 (52%), Gaps = 21/321 (6%) Query: 2 LALGIEGTAHTLGIGIVSEDKVLANVFDT-LTTEK--GGIHPKEAAEHHARLMKPLLRKA 58 + L IE + + IV+ V +NV + + T + GG+ P+ A+ H L+ L +A Sbjct: 3 IILAIETSCDETAVAIVNNRNVCSNVVSSQIQTHQIFGGVVPEVASRQHLLLINTCLDQA 62 Query: 59 LSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKMF 118 L +G+ +I+ IA + PGL AL V TAA+ LA+ ++KP +GV+H H+ + + Sbjct: 63 LQASGLGWPEIEAIAVTVAPGLAGALMVGVTAAKTLAMVHQKPFLGVHHLEGHIYASYLS 122 Query: 119 --GVKDP-VGLYVSGGNTQVLALEG-GRYRVFGETLDIGIGNAIDVFARELGLGFPGGPK 174 ++ P + L VSGG+T ++ ++G G YR G T D G A D AR L LG+PGGP Sbjct: 123 QPDLQPPFLCLLVSGGHTSLIHVKGCGDYRQLGTTRDDAAGEAFDKVARLLDLGYPGGPA 182 Query: 175 VEKLAEKG--------EKYIELPY-AVKGMDLSFSGLLTEAIR-----KYRSGKYRVEDL 220 +++ A++G E I LP D SFSGL T +R K S V+DL Sbjct: 183 IDRAAKQGDPGTFKLPEGKISLPQGGYHPYDSSFSGLKTAMLRLTQELKQSSAPLPVDDL 242 Query: 221 AYSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPY 280 A SFQ+T +L + T + V + + GGVAAN+RLR L+ ++ ++ F PP Sbjct: 243 AASFQDTVARSLTKKTIQCVLDHGLTTITVGGGVAANSRLRYHLQTAAQEHQLQVFFPPL 302 Query: 281 DLCRDNGAMIAYTGLRMYKAG 301 C DN AMIA ++ G Sbjct: 303 KFCTDNAAMIACAAADHFQNG 323 >gb|AAB82636.1| (AC002387) putative O-sialoglycoprotein endopeptidase [Arabidopsis thaliana] Length = 463 Score = 155 bits (388), Expect = 6e-37 Identities = 110/318 (34%), Positives = 171/318 (53%), Gaps = 17/318 (5%) Query: 1 MLALGIEGTAHTLGIGIVSEDKVLANVFDT-LTTEKGGIHPKEAAEHHARLMKPLLRKAL 59 ++ LGIE + +VS L++ L + GG+ PK+A E H+R++ +++ AL Sbjct: 84 LVVLGIETSCDDTAAAVVSPFNHLSSSCRAELLVQYGGVAPKQAEEAHSRVIDKVVQDAL 143 Query: 60 SEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKMFG 119 +A ++ D+ +A + GPGL LRV AR +A + PIVGV+H AH + ++ Sbjct: 144 DKANLTEKDLSAVAVTIGPGLSLCLRVGVRKARRVAGNFSLPIVGVHHMEAHALVARLVE 203 Query: 120 VK---DPVGLYVSGG-NTQVLALEGGRYRVFGETLDIGIGNAIDVFARELGLGF--PGGP 173 + + L +SGG N VLA + G+Y G T+D IG A D A+ LGL GGP Sbjct: 204 QELSFPFMALLISGGHNLLVLAHKLGQYTQLGTTVDDAIGEAFDKTAKWLGLDMHRSGGP 263 Query: 174 KVEKLAEKGE-KYIELPYAV---KGMDLSFSGLLTEAIRKYRSGKYRVE-DLAYSFQETA 228 VE+LA +G+ K ++ + K + S++GL T+ + + R D+A SFQ A Sbjct: 264 AVEELALEGDAKSVKFNVPMKYHKDCNFSYAGLKTQVRLAIEAKEIRNRADIAASFQRVA 323 Query: 229 FAALVEVTERAVAHTEKDE-----VVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLC 283 L E ERA+ + E +V+ GGVA+N +R L + E++ +K PP LC Sbjct: 324 VLHLEEKCERAIDWALELEPSIKHMVISGGVASNKYVRLRLNNIVENKNLKLVCPPPSLC 383 Query: 284 RDNGAMIAYTGLRMYKAG 301 DNG M+A+TGL ++ G Sbjct: 384 TDNGVMVAWTGLEHFRVG 401 >sp|O51710|GCP_BORBU PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROTEASE) >gi|7444712|pir||H70195 sialoglycoproteinase (gcp) homolog - Lyme disease spirochete >gi|2688702|gb|AAC67111.1| (AE001176) sialoglycoprotease (gcp) [Borrelia burgdorferi] Length = 346 Score = 152 bits (381), Expect = 4e-36 Identities = 104/315 (33%), Positives = 163/315 (51%), Gaps = 21/315 (6%) Query: 1 MLALGIEGTAHTLGIGIVSED-KVLANVFDTLTTEKG--GIHPKEAAEHHARLMKPLLRK 57 M LGIE + + +V +L+N+ T K GI P+ A+ H + + K Sbjct: 1 MKVLGIETSCDDCCVAVVENGIHILSNIKLNQTEHKKYYGIVPEIASRLHTEAIMSVCIK 60 Query: 58 ALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKM 117 AL +A + +ID+IA + PGL +L V A+ LA+ +KPI+ ++H + H+ M Sbjct: 61 ALKKANTKISEIDLIAVTSRPGLIGSLIVGLNFAKGLAISLKKPIICIDHILGHLYAPLM 120 Query: 118 FG-VKDP-VGLYVSGGNTQVLALEG-GRYRVFGETLDIGIGNAIDVFARELGLGFPGGPK 174 ++ P + L +SGG+T + + + G TLD G A D A+ +GFPGGP Sbjct: 121 HSKIEYPFISLLLSGGHTLIAKQKNFDDVEILGRTLDDACGEAFDKVAKHYDMGFPGGPN 180 Query: 175 VEKLAEKG-EKYIELPYAV-----KGMDLSFSGLLTEAIRKYRSGKYR-----VEDLAYS 223 +E++++ G E + P D S+SGL T I + K + ++A S Sbjct: 181 IEQISKNGDENTFQFPVTTFKKKENWYDFSYSGLKTACIHQLEKFKSKDNPTTKNNIAAS 240 Query: 224 FQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLC 283 FQ+ AF L+ +RA+ T+ +++V+ GGVA+N LRE + + I+ + PP DLC Sbjct: 241 FQKAAFENLITPLKRAIKDTQINKLVIAGGVASNLYLREKI----DKLKIQTYYPPLDLC 296 Query: 284 RDNGAMIAYTGLRMY 298 DNGAMIA G MY Sbjct: 297 TDNGAMIAGLGFNMY 311 >pir||A71545 probable o-sialoglycoprotein endopeptidase - Chlamydia trachomatis (serotype D, strain UW3/Cx) >gi|3328603|gb|AAC67789.1| (AE001293) O-Sialoglycoprotein Endopeptidase [Chlamydia trachomatis] Length = 338 Score = 149 bits (372), Expect = 5e-35 Identities = 100/318 (31%), Positives = 158/318 (49%), Gaps = 23/318 (7%) Query: 1 MLALGIEGTAHTLGIGIVSEDKVLANVFDT--LTTEKGGIHPKEAAEHHARLMKPLLRKA 58 ML LG+E + +V K+LAN + + GG+ P+ A+ H + LL A Sbjct: 1 MLTLGLESSCDETSCSLVQNGKILANKIASQDIHASYGGVIPELASRAHLQTFPELLTAA 60 Query: 59 LSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKMF 118 AGVSL+DI++I+ + PGL AL + A+ LA ++P++GVNH AH+ M Sbjct: 61 TQSAGVSLEDIELISVANTPGLIGALSIGVNFAKGLASGLKRPLIGVNHVEAHLYAACME 120 Query: 119 GVK---DPVGLYVSGGNTQVLAL-EGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGPK 174 +GL +SG +T + + + + + G+T D IG D AR LGL +PGG K Sbjct: 121 APATQFPALGLAISGAHTSLFLMPDATTFLLIGKTRDDAIGETFDKVARFLGLPYPGGQK 180 Query: 175 VEKLAEKG--EKYIELPYAVKGMDLSFSGLLTEAIRKYRS------------GKYRVEDL 220 +E+LA +G + + P V G D SFSGL T + + + + ++ Sbjct: 181 LEELAREGDADAFAFSPARVSGYDFSFSGLKTAVLYALKGNNSSAKAPFPEVSETQKRNI 240 Query: 221 AYSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPY 280 A SFQ+ F + + V + +++ GGVA N+ R R++ + + + P Sbjct: 241 AASFQKAVFMTIAQKLPDIVKTFSCESLIVGGGVANNSYFR---RLLNQICSLPIYFPSS 297 Query: 281 DLCRDNGAMIAYTGLRMY 298 LC DN AMIA G R++ Sbjct: 298 QLCSDNAAMIAGLGERLF 315 >pir||H72106 o-sialoglycoprotein endopeptidase - Chlamydophila pneumoniae (strain CWL029) >gi|4376465|gb|AAD18347.1| (AE001606) O-Sialoglycoprotein Endopeptidase [Chlamydophila pneumoniae CWL029] >gi|8163461|gb|AAF73688.1| (AE002216) O-sialoglycoprotein endopeptidase [Chlamydophila pneumoniae AR39] >gi|8978567|dbj|BAA98404.1| (AP002545) O-sialoglycoprotein endopeptidase [Chlamydophila pneumoniae J138] Length = 344 Score = 148 bits (371), Expect = 6e-35 Identities = 102/315 (32%), Positives = 156/315 (49%), Gaps = 24/315 (7%) Query: 1 MLALGIEGTAHTLGIGIVSEDK-VLANVFDT--LTTEKGGIHPKEAAEHHARLMKPLLRK 57 ML LG+E + IV+EDK +LAN+ + + GG+ P+ A+ H + ++ K Sbjct: 1 MLTLGLESSCDETACAIVNEDKQILANIIASQDIHASYGGVVPELASRAHLHIFPQVINK 60 Query: 58 ALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKM 117 AL +A + ++D+D+IA +Q PGL +L V + +A+ +K ++GVNH AH+ M Sbjct: 61 ALQQANLLIEDMDLIAVTQTPGLIGSLSVGVHFGKGIAIGAKKSLIGVNHVEAHLYAAYM 120 Query: 118 F--GVKDP-VGLYVSGGNTQVLALEG-GRYRVFGETLDIGIGNAIDVFARELGLGFPGGP 173 V+ P +GL VSG +T +E Y++ G+T D IG D R LGL +P GP Sbjct: 121 AAQNVQFPALGLVVSGAHTAAFFIENPTSYKLIGKTRDDAIGETFDKVGRFLGLPYPAGP 180 Query: 174 KVEKLAEKG--EKYIELPYAVKGMDLSFSGLLTEAIRKYRSGK------------YRVED 219 +EKLA +G + Y P V D SFSGL T + + + D Sbjct: 181 LIEKLALEGSEDSYPFSPAKVPNYDFSFSGLKTAVLYAIKGNNSSPRSPAPEISLEKQRD 240 Query: 220 LAYSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPP 279 +A SFQ+ A + + + +++ GGVA N R ++ + + PP Sbjct: 241 IAASFQKAACTTIAQKLPTIIKEFSCRSILIGGGVAINEYFRSAIQTAC---NLPVYFPP 297 Query: 280 YDLCRDNGAMIAYTG 294 LC DN AMIA G Sbjct: 298 AKLCSDNAAMIAGLG 312 >sp|Q50709|GCP_MYCTU PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROTEASE) >gi|7444707|pir||H70737 probable o-sialoglycoprotein endopeptidase - Mycobacterium tuberculosis (strain H37RV) >gi|1449368|emb|CAB01004.1| (Z77165) gcp [Mycobacterium tuberculosis] Length = 344 Score = 143 bits (357), Expect = 3e-33 Identities = 110/320 (34%), Positives = 155/320 (48%), Gaps = 24/320 (7%) Query: 4 LGIEGTAHTLGIGIVSEDK-----VLANVFDTLTTEK---GGIHPKEAAEHHARLMKPLL 55 LGIE + G+GI D +LA+ + E GG+ P+ A+ H + P + Sbjct: 5 LGIETSCDETGVGIARLDPDGTVTLLADEVASSVDEHVRFGGVVPEIASRAHLEALGPAM 64 Query: 56 RKALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHV--E 113 R+AL+ AG L D++A + GPGL AL V AA+A + + P VNH H+ + Sbjct: 65 RRALAAAG--LKQPDIVAATIGPGLAGALLVGVAAAKAYSAAWGVPFYAVNHLGGHLAAD 122 Query: 114 ITKMFGVKDPVGLYVSGGNTQVLALE--GGRYRVFGETLDIGIGNAIDVFARELGLGFPG 171 + + + + V L VSGG+T +L + G G T+D G A D AR LGLG+PG Sbjct: 123 VYEHGPLPECVALLVSGGHTHLLHVRSLGEPIIELGSTVDDAAGEAYDKVARLLGLGYPG 182 Query: 172 GPKVEKLAEKGEK-YIELPYAVKG-----MDLSFSGLLTEAIRKYRSGK----YRVEDLA 221 G ++ LA G++ I P + G SFSGL T R S +R D+A Sbjct: 183 GKALDDLARTGDRDAIVFPRGMSGPADDRYAFSFSGLKTAVARYVESHAADPGFRTADIA 242 Query: 222 YSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYD 281 FQE L RA +++ GGVAAN+RLRE+ + G +P Sbjct: 243 AGFQEAVADVLTMKAVRAATALGVSTLLIAGGVAANSRLRELATQRCGEAGRTLRIPSPR 302 Query: 282 LCRDNGAMIAYTGLRMYKAG 301 LC DNGAMIA ++ AG Sbjct: 303 LCTDNGAMIAAFAAQLVAAG 322 >sp|P57166|GCP_BUCAI PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROTEASE) >gi|10038746|dbj|BAB12781.1| (AP001118) O-sialoglycoprotein endopeptidase [Buchnera sp. APS] Length = 336 Score = 143 bits (357), Expect = 3e-33 Identities = 111/337 (32%), Positives = 173/337 (50%), Gaps = 20/337 (5%) Query: 1 MLALGIEGTAHTLGIGIVSEDK--VLANVFDT--LTTEKGGIHPKEAAEHHARLMKPLLR 56 M LGIE + GI I +K ++ +++ L GGI P+ A+ H M LL Sbjct: 1 MRILGIETSCDDTGIAIYDTNKGLLINEIYNQRKLNNIYGGIIPELASREHMEAMIVLLN 60 Query: 57 KALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITK 116 K + + +D+IA++ GPGL +L V AT A +L + P++ V+H AH+ ++ Sbjct: 61 KIFKKKNI-YKYVDMIAYTAGPGLIGSLLVGATFACSLGLSLNIPVLPVHHMEAHL-LSP 118 Query: 117 MFGVKDP----VGLYVSGGNTQVL-ALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPG 171 M K +GL VSG +TQ++ A + G Y + G LD G A D A+ LGL +PG Sbjct: 119 MLDYKTIQFPFIGLLVSGKHTQIIGAHKFGEYEILGNCLDDAAGEAFDKTAKLLGLKYPG 178 Query: 172 GPKVEKLAEKGEK-YIELPYAV---KGMDLSFSGLLT---EAIRKYRSGKYRVEDLAYSF 224 G ++ KLA KG K Y P + ++ SFSGL T + I+K ++A +F Sbjct: 179 GLELSKLASKGIKDYFYFPRPMIHHSDLNFSFSGLKTFAAQTIKKSSKSMQEKANIAKAF 238 Query: 225 QETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDR-GIKFFVPPYDLC 283 ++ L+ T++A+ + +V+ GGV+AN +LR+ IM + F + C Sbjct: 239 EDAVIDILLIKTKKALKKQKWKRLVIAGGVSANQKLRKKSEIMVKKNFNGTVFYSSLEFC 298 Query: 284 RDNGAMIAYTGLRMYKAGISFRLEETIVKQKFRTDEV 320 DN AMIAY G K + +L E +VK K+ D++ Sbjct: 299 TDNAAMIAYLGSLRQKEARNSQL-EILVKPKWSIDDL 334 >gb|AAF73560.1| (AE002315) O-sialoglycoprotein endopeptidase [Chlamydia muridarum] Length = 340 Score = 143 bits (356), Expect = 4e-33 Identities = 100/318 (31%), Positives = 157/318 (48%), Gaps = 23/318 (7%) Query: 1 MLALGIEGTAHTLGIGIVSEDKVLAN--VFDTLTTEKGGIHPKEAAEHHARLMKPLLRKA 58 ML LG+E + +V K+LAN + GG+ P+ A+ H ++ LL Sbjct: 1 MLTLGLESSCDETSCALVENGKILANRIASQDIHAAYGGVIPELASRAHLQIFPKLLAAV 60 Query: 59 LSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKMF 118 +A VSL+D+++I+ + PGL AL V A+ LA +K ++GVNH AH+ + Sbjct: 61 AQDAEVSLEDVELISVANTPGLIGALSVGVNFAKGLASGLKKTLIGVNHVEAHLYAACLE 120 Query: 119 --GVKDP-VGLYVSGGNTQVLALEGG-RYRVFGETLDIGIGNAIDVFARELGLGFPGGPK 174 ++ P +GL +SG +T + + + + G+T D IG D AR LGL +PGG K Sbjct: 121 EPSIRFPALGLAISGAHTSLFLMPNATTFLLIGKTRDDAIGETFDKVARFLGLPYPGGQK 180 Query: 175 VEKLAEKG--EKYIELPYAVKGMDLSFSGLLTEAIRKYRS------------GKYRVEDL 220 +E+LA+ G E Y V G D SFSGL T + + + + ++ Sbjct: 181 LEELAQDGDEEAYPFSRAKVSGNDFSFSGLKTAVLYALKGNNSSAKAPFPEVSETQKRNI 240 Query: 221 AYSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPY 280 A SFQ+ AF + + V + +++ GGVA N R R++ + + + P Sbjct: 241 AASFQKAAFMTIAQKLPDIVKAFSCESLIVGGGVANNRYFR---RLLNQTCSLPTYFPSS 297 Query: 281 DLCRDNGAMIAYTGLRMY 298 LC DN AMIA G R++ Sbjct: 298 QLCSDNAAMIAGLGERLF 315 >sp|Q9ZEA8|GCP_RICPR PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROTEASE) >gi|7444723|pir||E71711 probable o-sialoglycoprotein endopeptidase (gcp) RP037 - Rickettsia prowazekii >gi|3860607|emb|CAA14508.1| (AJ235270) PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (gcp) [Rickettsia prowazekii] Length = 387 Score = 141 bits (352), Expect = 1e-32 Identities = 112/363 (30%), Positives = 164/363 (44%), Gaps = 69/363 (19%) Query: 4 LGIEGTAHTLGIGIVSED-KVLANVFDTLTTEK---GGIHPKEAAEHHARLMKPLLRKAL 59 LGIE + I I++E K+L+N+ + TE GG+ P+ AA H + L+ L Sbjct: 5 LGIESSCDDTAISIITERRKILSNIIISQNTEHAVFGGVVPEIAARSHLSNLDQALKNVL 64 Query: 60 SEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKMF- 118 ++ L +I IA + GPGL + V + AR+L+ +KP + +NH H ++ Sbjct: 65 KKSNTELTEISAIAATSGPGLIGGVIVGSMFARSLSSALKKPFIAINHLEGHALTARLTD 124 Query: 119 GVKDP-VGLYVSGGNTQVLALEG-GRYRVFGETLDIGIGNAIDVFARELGLGFPGGPKVE 176 + P + L SGG+ Q +A+ G G+Y++ G T+D +G D A+ L L FPGGP++E Sbjct: 125 NISYPYLLLLASGGHCQFVAVLGLGKYKILGTTIDDAVGETFDKVAKMLNLSFPGGPEIE 184 Query: 177 KLAEKGEKY-IELPYAV---KGMDLSFSGLLTEAIRKYRSGKYRV-----EDLAYSFQET 227 K A+ G + + P + ++SFSGL T A+R V D+A SFQ T Sbjct: 185 KRAKLGNPHKYKFPKPIINSGNCNMSFSGLKT-AVRTLIMNLKEVNDSVINDIAASFQFT 243 Query: 228 AFAALVEVTERAVA--------------HTEK---------------------------- 245 A L + A+ H K Sbjct: 244 IGAILSSKMQDAIRLYKQILNDYYEDINHPTKLNLKSFRKDEFNWKPLECITRPKYRIHI 303 Query: 246 ----------DEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGL 295 D +V+ GGVAAN L+E+L T G + PP LC DN AMIAY GL Sbjct: 304 QNSYRSNLLNDTIVIAGGVAANKYLQEILSDCTRPYGYRLIAPPMHLCTDNAAMIAYAGL 363 Query: 296 RMY 298 Y Sbjct: 364 ERY 366 >sp|P37969|GCP_MYCLE PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROTEASE) >gi|2145944|pir||S72817 probable glycoproteinase - Mycobacterium leprae >gi|466938|gb|AAC43226.1| (U00015) u1620c; B1620_C3_226 [Mycobacterium leprae] Length = 351 Score = 133 bits (332), Expect = 2e-30 Identities = 108/310 (34%), Positives = 153/310 (48%), Gaps = 20/310 (6%) Query: 2 LALGIEGTAHTLGIGIVSEDK-----VLANVFDTLTTEK---GGIHPKEAAEHHARLMKP 53 + L IE + G+GI D +LA+ + E+ GG+ P+ A+ H + P Sbjct: 10 IILAIETSCDETGVGIACLDDYGTVTLLADEVASSVDEQARFGGVVPEIASRAHLEALGP 69 Query: 54 LLRKALSEAGVSLD-DIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHV 112 +R AL+ AG++ DV+A + GPGL AL V AA+A + + P VNH H+ Sbjct: 70 TIRCALAAAGLTGSAKPDVVAATIGPGLAGALLVGVAAAKAYSAAWGVPFYAVNHLGGHL 129 Query: 113 --EITKMFGVKDPVGLYVSGGNTQVLALE--GGRYRVFGETLDIGIGNAIDVFARELGLG 168 ++ + + + V L VSGG+T +L + G G T+D G A D AR LGLG Sbjct: 130 AADVYEHGPLPECVALLVSGGHTHLLQVRSLGAPIVELGSTVDDAAGEAYDKVARLLGLG 189 Query: 169 FPGGPKVEKLAEKGEK-YIELPYAVKGM--DL---SFSGLLTEAIRKYRSGKYRVE-DLA 221 +PGG ++ LA G++ I P + G DL SFSGL T R S + D+A Sbjct: 190 YPGGKVLDDLARTGDRDAIVFPRGMTGPADDLNAFSFSGLKTAVARYVESHPDALPADVA 249 Query: 222 YSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYD 281 FQE L RA +++VGGVAAN+RLRE+ G+ +P Sbjct: 250 AGFQEAVADVLTMKAVRAATGLGVSTLLIVGGVAANSRLRELAAQRCAAAGLMLRIPGPR 309 Query: 282 LCRDNGAMIA 291 C DNGAMIA Sbjct: 310 FCTDNGAMIA 319 >sp|O83686|GCP_TREPA PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROTEASE) >gi|7444717|pir||H71294 probable o-sialoglycoprotein endopeptidase (gcp) - syphilis spirochete >gi|3322977|gb|AAC65643.1| (AE001242) o-sialoglycoprotein endopeptidase (gcp) [Treponema pallidum] Length = 352 Score = 125 bits (312), Expect = 5e-28 Identities = 105/317 (33%), Positives = 151/317 (47%), Gaps = 27/317 (8%) Query: 1 MLALGIEGTAHTLGIGIVSEDK-VLANVFDT---LTTEKGGIHPKEAAEHHARLMKPLLR 56 M LGIE + + IV + V +NV T GI P+ A+ H + P ++ Sbjct: 1 MNVLGIETSCDETAVAIVKDGTHVCSNVVATQIPFHAPYRGIVPELASRKHIEWILPTVK 60 Query: 57 KALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNH-----CIAH 111 +AL+ A ++L DID IA + PGL +L V T A+ LA P + VNH C AH Sbjct: 61 EALARAQLTLADIDGIAVTHAPGLTGSLLVGLTFAKTLAWSMHLPFIAVNHLHAHFCAAH 120 Query: 112 VEITKMFGVKDPVGLYVSGGNTQVLAL-EGGRYRVFGETLDIGIGNAIDVFARELGLGFP 170 VE + VGL SGG+ V + + + G T+D G A D A G G+P Sbjct: 121 VEHDLAYPY---VGLLASGGHALVCVVHDFDQVEALGATIDDAPGEAFDKVAAFYGFGYP 177 Query: 171 GGPKVEKLAEKGE---KYIELP-YAVKG--MDLSFSGLLTEAIRKY-----RSGKYRVED 219 GG +E LAE+G+ LP + KG D+S+SGL T I + + + ++ Sbjct: 178 GGKVIETLAEQGDARAARFPLPHFHGKGHRYDVSYSGLKTAVIHQLDHFWNKEYERTAQN 237 Query: 220 LAYSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPP 279 +A +FQ A L+ RA+ T V+ GGVAAN+ LR+ + R + P Sbjct: 238 IAAAFQACAINILLRPLARALQDTGLPTAVVCGGVAANSLLRKSVADWKHARCV---FPS 294 Query: 280 YDLCRDNGAMIAYTGLR 296 + C DN M+A G R Sbjct: 295 REYCTDNAVMVAALGYR 311 >gi|6320099 similar to H.influenzae sialoglycoprotease; Qri7p [Saccharomyces cerevisiae] >gi|1172805|sp|P43122|QRI7_YEAST PUTATIVE PROTEASE QRI7 >gi|1077467|pir||S50740 QRI7 protein - yeast (Saccharomyces cerevisiae) >gi|683704|emb|CAA55926.1| (X79380) QRI7 [Saccharomyces cerevisiae] >gi|1199545|emb|CAA64909.1| (X95644) ORF 2358 [Saccharomyces cerevisiae] >gi|1431146|emb|CAA98671.1| (Z74152) ORF YDL104c [Saccharomyces cerevisiae] Length = 407 Score = 124 bits (309), Expect = 1e-27 Identities = 103/324 (31%), Positives = 163/324 (49%), Gaps = 54/324 (16%) Query: 23 VLANVFDTLTT-EKGGIHPKEAAEHHARLMKPLLRKALSEAGVSLDDIDVIAFSQGPGLG 81 VLAN+ DTL + ++GGI P +A HH + PL +AL E+ + ID+I ++GPG+ Sbjct: 61 VLANLKDTLDSIDEGGIIPTKAHIHHQARIGPLTERALIESNAR-EGIDLICVTRGPGMP 119 Query: 82 PALRVVATAARALAVKYRKPIVGVNHCIAHVEITKM-FGVKDP----VGLYVSGGNTQ-V 135 +L A+ LAV + KP++GV+H + H+ I +M K P V L VSGG+T V Sbjct: 120 GSLSGGLDFAKGLAVAWNKPLIGVHHMLGHLLIPRMGTNGKVPQFPFVSLLVSGGHTTFV 179 Query: 136 LALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGPKVEKLAEKGEKYI--------- 186 L+ + + +T+DI +G+++D RELG K +A + EK+I Sbjct: 180 LSRAIDDHEILCDTIDIAVGDSLDKCGRELGF------KGTMIAREMEKFINQDINDQDF 233 Query: 187 ----ELPYAVKG-------MDLSFSGLLTEAIRK--YRSGKYRVEDL--------AYSFQ 225 E+P +K + SFS +T A+R + GK +++L AY Q Sbjct: 234 ALKLEMPSPLKNSASKRNMLSFSFSAFIT-ALRTNLTKLGKTEIQELPEREIRSIAYQVQ 292 Query: 226 ETAFAALVEVTERAV-AHTEK----DEVVLVGGVAANNRLREMLR----IMTEDRGIKFF 276 E+ F ++ + + + EK E V GGV++N RLR L + F+ Sbjct: 293 ESVFDHIINKLKHVLKSQPEKFKNVREFVCSGGVSSNQRLRTKLETELGTLNSTSFFNFY 352 Query: 277 VPPYDLCRDNGAMIAYTGLRMYKA 300 PP DLC DN MI + G+ ++++ Sbjct: 353 YPPMDLCSDNSIMIGWAGIEIWES 376 >sp|P75055|GCP_MYCPN PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROTEASE) >gi|2146478|pir||S73421 o-sialoglycoprotein endopeptidase - Mycoplasma pneumoniae (strain ATCC 29342) >gi|1673750|gb|AAB95743.1| (AE000011) o-sialoglycoprotein endopeptidase [Mycoplasma pneumoniae] Length = 319 Score = 123 bits (306), Expect = 3e-27 Identities = 95/312 (30%), Positives = 153/312 (48%), Gaps = 34/312 (10%) Query: 4 LGIEGTAHTLGIGIVSEDKVLANVFDT---LTTEKGGIHPKEAAEHHARLMKPLLRKALS 60 LGIE T IG+++E KV A++ + L + GG+ P+ AA H + L KAL Sbjct: 8 LGIETTCDDTSIGVITESKVQAHIVLSSAKLHAQTGGVVPEVAARSHEQN----LLKALQ 63 Query: 61 EAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHV-------E 113 ++GV L+ I IA++ PGL L V AT AR+L+ KP++ +NH AH+ + Sbjct: 64 QSGVVLEQITHIAYAANPGLPGCLHVGATFARSLSFLLDKPLLPINHLYAHIFSALIDQD 123 Query: 114 ITKMFGVKDP-VGLYVSGGNTQVLALEG-GRYRVFGETLDIGIGNAIDVFARELGLGFPG 171 I ++ K P +GL VSGG+T + ++ + ET D IG D R +G +P Sbjct: 124 INQL---KLPALGLVVSGGHTAIYLIKSLFDLELIAETSDDAIGEVYDKVGRAMGFPYPA 180 Query: 172 GPKVEKL--AEKGEKYIELPYAVKGMDLSFSGLLTEAIRKYRSGKYRV---------EDL 220 GP+++ L E + + + K S+SGL ++ K + + R + Sbjct: 181 GPQLDSLFQPELVKSHYFFRPSTKWTKFSYSGLKSQCFTKIKQLRERKGFNPQTHDWNEF 240 Query: 221 AYSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPY 280 A +FQ T + + A+ + ++L GGV+AN LRE + + + + + P Sbjct: 241 ASNFQATIIDHYINHVKDAIQQHQPQMLLLGGGVSANKYLREQVTQLQ----LPYLIAPL 296 Query: 281 DLCRDNGAMIAY 292 DNGAMI + Sbjct: 297 KYTSDNGAMIGF 308 >sp|P47292|GCP_MYCGE PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROTEASE) >gi|1361848|pir||A64205 O-sialoglycoprotein endopeptidase (EC 3.4.24.57) homolog - Mycoplasma genitalium >gi|3844655|gb|AAC71262.1| (U39684) O-sialoglycoprotein endopeptidase [Mycoplasma genitalium] Length = 315 Score = 115 bits (284), Expect = 1e-24 Identities = 86/310 (27%), Positives = 150/310 (47%), Gaps = 28/310 (9%) Query: 1 MLALGIEGTAHTLGIGIVSEDKVLANVFDT---LTTEKGGIHPKEAAEHHARLMKPLLRK 57 + LGIE T G+ IV + K+ +N+ + L + GG+ P+ AA H + L K Sbjct: 5 LCVLGIETTCDDTGLSIVIDQKIKSNIVISSANLHVKTGGVVPEIAARCHEQN----LFK 60 Query: 58 ALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHV----- 112 A+ + + D+ IA++ PGL L V AT AR+L+ KP++ +NH AH+ Sbjct: 61 AIRDLNFEIRDLSHIAYACNPGLAGCLHVGATFARSLSFLLDKPLLPINHLYAHIFSCLI 120 Query: 113 --EITKMFGVKDPVGLYVSGGNTQVLALEG-GRYRVFGETLDIGIGNAIDVFARELGLGF 169 ++ K+ +GL +SGG+T + ++ + ET D IG D R +G + Sbjct: 121 DQDLNKL--QLPALGLVISGGHTAIYLVKSFYELELIAETSDDAIGEVYDKIGRAMGFDY 178 Query: 170 PGGPKVEKLAEKG--EKYIELPYAVKGMDLSFSGLLTEAIRKYR---SGKYRVE--DLAY 222 P G K++ L K + + + K S+SGL ++ + K + + K R++ +LA Sbjct: 179 PAGSKIDSLFNKELVKPHYFFKPSTKWTKFSYSGLKSQCLNKIKQISANKTRIDWSELAS 238 Query: 223 SFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDL 282 +FQ T ++ + A+ +++ GGV+AN+ L + + + F + Sbjct: 239 NFQATIIDHYIDHVKNAIKKFAPKMLLVGGGVSANSYLSNRISTL----NLPFLIADSKY 294 Query: 283 CRDNGAMIAY 292 DNGAMI + Sbjct: 295 TSDNGAMIGF 304 >pir||S72996 probable glycoproteinase u229e - Mycobacterium leprae >gi|467128|gb|AAA17310.1| (U00020) u229e; B229_C3_246 [Mycobacterium leprae] Length = 290 Score = 112 bits (277), Expect = 6e-24 Identities = 95/278 (34%), Positives = 137/278 (49%), Gaps = 20/278 (7%) Query: 2 LALGIEGTAHTLGIGIVSEDK-----VLANVFDTLTTEK---GGIHPKEAAEHHARLMKP 53 + L IE + G+GI D +LA+ + E+ GG+ P+ A+ H + P Sbjct: 10 IILAIETSCDETGVGIACLDDYGTVTLLADEVASSVDEQARFGGVVPEIASRAHLEALGP 69 Query: 54 LLRKALSEAGVSLD-DIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHV 112 +R AL+ AG++ DV+A + GPGL AL V AA+A + + P VNH H+ Sbjct: 70 TIRCALAAAGLTGSAKPDVVAATIGPGLAGALLVGVAAAKAYSAAWGVPFYAVNHLGGHL 129 Query: 113 --EITKMFGVKDPVGLYVSGGNTQVLALE--GGRYRVFGETLDIGIGNAIDVFARELGLG 168 ++ + + + V L VSGG+T +L + G G T+D G A D AR LGLG Sbjct: 130 AADVYEHGPLPECVALLVSGGHTHLLQVRSLGAPIVELGSTVDDAAGEAYDKVARLLGLG 189 Query: 169 FPGGPKVEKLAEKGEK-YIELPYAVKGM--DL---SFSGLLTEAIRKYRSGKYRV-EDLA 221 +PGG ++ LA G++ I P + G DL SFSGL T R S + D+A Sbjct: 190 YPGGKVLDDLARTGDRDAIVFPRGMTGPADDLNAFSFSGLKTAVARYVESHPDALPADVA 249 Query: 222 YSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNR 259 FQE L RA +++VGGVAAN+R Sbjct: 250 AGFQEAVADVLTMKAVRAATGLGVSTLLIVGGVAANSR 287 >gi|11641265 putative sialoglycoprotease type 2 [Homo sapiens] >gi|11071727|emb|CAC14666.1| (AJ295148) putative sialoglycoprotease type 2 [Homo sapiens] Length = 439 Score = 110 bits (273), Expect = 2e-23 Identities = 101/363 (27%), Positives = 166/363 (44%), Gaps = 62/363 (17%) Query: 2 LALGIEGTAHTLGIGIVSED-KVLANVFDTLTT---EKGGIHPKEAAEHHARLMKPLLRK 57 + LGIE + +V E VL + T + GGI P A + H ++ ++++ Sbjct: 38 IVLGIETSCDDTAAAVVDETGNVLGEAIHSQTEVHLKTGGIVPPAAQQLHRENIQRIVQE 97 Query: 58 ALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKM 117 ALS +GVS D+ IA + PGL +L V + + L + +KP + ++H AH ++ Sbjct: 98 ALSASGVSPSDLSAIATTIKPGLALSLGVGLSFSLQLVGQLKKPFIPIHHMEAHALTIRL 157 Query: 118 FG-VKDP-VGLYVSGGNTQVLALEG-GRYRVFGETLDIGIGNAIDVFARELGL------- 167 V+ P + L +SGG+ + ++G + + G++LDI G+ +D AR L L Sbjct: 158 TNKVEFPFLVLLISGGHCLLALVQGVSDFLLLGKSLDIAPGDMLDKVARRLSLIKHPECS 217 Query: 168 GFPGGPKVEKLAEKGEKY---IELP-YAVKGMDLSFSGL--LTEAI-------------- 207 GG +E LA++G ++ I+ P + K D SF+GL +T+ I Sbjct: 218 TMSGGKAIEHLAKQGNRFHFDIKPPLHHAKNCDFSFTGLQHVTDKIIMKKEKEEGIFLIS 277 Query: 208 ------------------RKYRSGKY--RVEDLAYSFQETAFAALVEVTERAVAHTEKDE 247 +Y G+ D+A + Q T LV+ T RA+ ++ + Sbjct: 278 KVEQINIPGLCLKIAAHFCRYEKGQILSSAADIAATVQHTMACHLVKRTHRAILFCKQRD 337 Query: 248 --------VVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGLRMYK 299 +V GGVA+N +R L I+T PP LC DNG MIA+ G+ + Sbjct: 338 LLPQNNAVLVASGGVASNFYIRRALEILTNATQCTLLCPPPRLCTDNGIMIAWNGIERLR 397 Query: 300 AGI 302 G+ Sbjct: 398 GGL 400 >pir||T40899 probable proteinase - fission yeast (Schizosaccharomyces pombe) >gi|4049543|emb|CAA22548.1| (AL034564) putative protease; endopeptidase [Schizosaccharomyces pombe] Length = 412 Score = 109 bits (269), Expect = 6e-23 Identities = 88/297 (29%), Positives = 140/297 (46%), Gaps = 32/297 (10%) Query: 36 GGIHPKEAAEHHARLMKPLLRKALSEAGVS-LDDIDVIAFSQGPGLGPALRVVATAARAL 94 GGIHP H + + ++++ +S+A S + D D+IA ++GPG+ L V A+ L Sbjct: 85 GGIHPTIVIHEHQKNLAKVIQRTISDAARSGITDFDLIAVTRGPGMIGPLAVGLNTAKGL 144 Query: 95 AVKYRKPIVGVNHCIAH---VEITKMFGVKDPVGLYVSGGNTQVLALEG-GRYRVFGETL 150 AV +KP++ V+H AH V++ K + + VSGG+T ++ + + T Sbjct: 145 AVGLQKPLLAVHHMQAHALAVQLEKSIDF-PYLNILVSGGHTMLVYSNSLLNHEIIVTTS 203 Query: 151 DIGIGNAIDVFARELGLGFPGGPKVEKLAEKGEKYI-ELPYAVK------------GMDL 197 DI +G+ +D A+ LG+ + L + I Y++K Sbjct: 204 DIAVGDYLDKCAKYLGIPWDNEMPAAALEQFASPEINSTSYSLKPPIPLNTREKVHSASF 263 Query: 198 SFSGLLTEAIRKYRSGKYRVED---LAYSFQETAFAALVEVTERAVAHTEKDEV---VLV 251 SFSGL + A R R + + AY Q AF + + T A+ + +V V Sbjct: 264 SFSGLESYACRIIRKTPLNLSEKKFFAYQLQYAAFQHICQKTLLALKRLDLSKVKYLVCS 323 Query: 252 GGVAANNRLREM-------LRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGLRMYKAG 301 GGVA N L++M L+ + IK P D+C DN AMI YT ++M+KAG Sbjct: 324 GGVARNELLKKMLNDTLMVLQFEHQPTDIKLVYPSPDICSDNAAMIGYTAIQMFKAG 380 >pir||T18825 hypothetical protein C01G10.10 - Caenorhabditis elegans >gi|3873878|emb|CAB02716.1| (Z81030) contains similarity to Pfam domain: PF00814 (Glycoprotease family), Score=577.5, E-value=2.8e-170, N=1~cDNA EST yk113e2.3 comes from this gene~cDNA EST yk113e2.5 comes from this gene~cDNA EST yk342g8.3 comes from this gene~cDNA EST yk342g8.5 c> Length = 421 Score = 103 bits (254), Expect = 3e-21 Identities = 93/326 (28%), Positives = 155/326 (47%), Gaps = 34/326 (10%) Query: 4 LGIEGTAHTLGIGIVSEDKVLAN----VFDTLTTEKGGIHPKEAAEHHARLMKPLLRKAL 59 LGIE + + IV+E + + + + ++GGI+P A H + L+ K L Sbjct: 26 LGIETSCDDTAVAIVNEKREILSSERYTERAIQRQQGGINPSVCALQHRENLPRLIEKCL 85 Query: 60 SEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKMFG 119 ++AG S D+D +A + PGL AL+ +AA A K+R P++ V+H AH + Sbjct: 86 NDAGTSPKDLDAVAVTVTPGLVIALKEGISAAIGFAKKHRLPLIPVHHMRAHA--LSILL 143 Query: 120 VKDPV-----GLYVSGGNTQV-LALEGGRYRVFGETLDIGIGNAIDVFARELG-LG--FP 170 V D V + +SGG+ + +A + +++++G+++ G ID AR+LG LG F Sbjct: 144 VDDSVRFPFSAVLLSGGHALISVAEDVEKFKLYGQSVSGSPGECIDKVARQLGDLGSEFD 203 Query: 171 G---GPKVEKLAEKGEKYIELPYA-----VKGMDLSFSGL------LTEAIRKYRSGKYR 216 G G VE LA + L Y V +++F + L E +RK Sbjct: 204 GIHVGAAVEILASRASADGHLRYPIFLPNVPKANMNFDQIKGSYLNLLERLRKNSETSID 263 Query: 217 VEDLAYSFQETA---FAALVEVTERAVAHTEK--DEVVLVGGVAANNRLREMLRIMTEDR 271 + D S Q T ++ + + +++ EK ++V+ GGVAAN + + ++ Sbjct: 264 IPDFCASLQNTVARHISSKLHIFFESLSEQEKLPKQLVIGGGVAANQYIFGAISKLSAAH 323 Query: 272 GIKFFVPPYDLCRDNGAMIAYTGLRM 297 + LC DN MIAY+GL M Sbjct: 324 NVTTIKVLLSLCTDNAEMIAYSGLLM 349 >pir||H82894 sialoglycoproteinase UU411 [imported] - Ureaplasma urealyticum >gi|6899399|gb|AAF30822.1|AE002138_9 (AE002138) sialoglycoprotease [Ureaplasma urealyticum] Length = 320 Score = 101 bits (249), Expect = 1e-20 Identities = 87/321 (27%), Positives = 152/321 (47%), Gaps = 29/321 (9%) Query: 2 LALGIEGTAHTLGIGIVSEDKVLANVFDT---LTTEKGGIHPKEAAEHHARLMKPLLRKA 58 L L IE + + + +K++A+ + + + GG+ P+ A+ +H + + L + Sbjct: 6 LILSIESSCDETSLALFENNKLIAHKISSSASIQSLHGGVVPELASRYHEQNINHLFNEI 65 Query: 59 LSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHV------ 112 L+E ++ I +A++ PGL L V A+ LAV +V +NH AHV Sbjct: 66 LNETKINPLTITHVAYTAMPGLPGCLHVGKVFAKQLAVLINAELVPINHLHAHVFSASIN 125 Query: 113 -EITKMFGVKDPVGLYVSGGNTQV-LALEGGRYRVFGETLDIGIGNAIDVFARELGLGFP 170 +T F +GL VSGG + + L + +V +T D IG D AR LG +P Sbjct: 126 QNLTFPF-----LGLVVSGGESCIYLVNDYDEIKVLNQTHDDAIGECYDKIARVLGWKYP 180 Query: 171 GGPKVEKLAEKGEKYIE-LPYAVKGMDLSFSGLLTEAIRKYRSGKYRVED-----LAYSF 224 GGP ++K ++ +E + D SFSGL T I + K + +A SF Sbjct: 181 GGPIIDKNYQENLATLEFIKSQPAAKDFSFSGLKTAVINYIHNAKQKKISFDPVVVASSF 240 Query: 225 QETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCR 284 Q+ A +++ + + + + + + GGV+AN+ LR+ ++ + + ++P Sbjct: 241 QKFAINEIIKKIKYYLNLYKLNHLAIGGGVSANSLLRKKIQSL----DVISYIPEMIYTG 296 Query: 285 DNGAMI---AYTGLRMYKAGI 302 DN AMI AY ++ +K I Sbjct: 297 DNAAMIGAYAYALIKNHKKSI 317 >pir||E81278 probable glycoproteinase Cj1344c [imported] - Campylobacter jejuni (strain NCTC 11168) >gi|6968778|emb|CAB73771.1| (AL139078) putative glycoprotease [Campylobacter jejuni] Length = 335 Score = 99.1 bits (243), Expect = 6e-20 Identities = 86/334 (25%), Positives = 147/334 (43%), Gaps = 30/334 (8%) Query: 2 LALGIEGTAHTLGIGIVSEDKVLANVFDTLTTEK-----GGIHPKEAAEHHARLMKPLLR 56 L L IE + I I+ ++ + ++ E GG+ P+ AA H+ + +L+ Sbjct: 4 LILAIESSCDDSSIAIIDKNTLECKFHKKISQELDHSIYGGVVPELAARLHSEALPKMLK 63 Query: 57 KALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHV---- 112 + ++ IA + PGL +L + A+ LA P++ +NH H+ Sbjct: 64 QCKEH----FKNLCAIAVTNEPGLSVSLLSGISMAKTLASALNLPLIPINHLKGHIYSLF 119 Query: 113 ---EITKMFGVKDPVGLYVSGGNTQVLAL-EGGRYRVFGETLDIGIGNAIDVFARELGLG 168 +I+ G+ L VSGG+T VL L + + T D G + D A+ + LG Sbjct: 120 LEEKISLDMGI-----LLVSGGHTMVLYLKDDASLELLASTNDDSFGESFDKVAKMMNLG 174 Query: 169 FPGGPKVEKLAEKGE-KYIELPYAVKG---MDLSFSGLLT----EAIRKYRSGKYRVEDL 220 +PGG +E LA+ + K I +K + SFSGL E ++ + ++ Sbjct: 175 YPGGVIIENLAKNAKLKNISFNTPLKHSKELAFSFSGLKNAVRLEILKHENLNEDTKAEI 234 Query: 221 AYSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPY 280 AY+F+ TA +++ E+ + +VGG +AN LR L+ + + + P Sbjct: 235 AYAFENTACDHIMDKLEKIFNLYKFKNFGVVGGASANLNLRSRLQNLCQKYNANLKLAPL 294 Query: 281 DLCRDNGAMIAYTGLRMYKAGISFRLEETIVKQK 314 C DN MIA + Y+ +EE I+ K Sbjct: 295 KFCSDNALMIARAAVDAYEKKEFVSVEEDILSPK 328 >gb|AAF49008.1| (AE003513) CG14231 gene product [Drosophila melanogaster] Length = 409 Score = 97.1 bits (238), Expect = 2e-19 Identities = 94/336 (27%), Positives = 148/336 (43%), Gaps = 46/336 (13%) Query: 4 LGIEGTAHTLGIGIV-SEDKVLANVFDT---LTTEKGGIHPKEAAEHHARLMKPLLRKAL 59 LGIE + GI IV + +V+ANV ++ T GGI P A + H ++ ++ + Sbjct: 28 LGIETSCDDTGIAIVDTTGRVIANVLESQQEFHTRYGGIIPPRAQDLHRARIESAYQRCM 87 Query: 60 SEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKMFG 119 A + D + IA + PGL +L V AR LA + +KP++ V+H AH +M Sbjct: 88 EAAQLKPDQLTAIAVTTRPGLPLSLLVGVRFARHLARRLQKPLLPVHHMEAHALQARM-E 146 Query: 120 VKDPVG-----LYVSGGNTQVLALEG-GRYRVFGETLDIGIGNAIDVFARELGLG----- 168 + +G L SGG+ Q++ G GR + G+TLD G A D R L L Sbjct: 147 HPEQIGYPFLCLLASGGHCQLVVANGPGRLTLLGQTLDDAPGEAFDKIGRRLRLHILPEY 206 Query: 169 --FPGGPKVEKLAEKGEKYI----ELPYA-VKGMDLSFSGLLTEAIRKYRSGKYRVE--- 218 + GG +E A+ + LP A + + SF+G+ + R R+ + R E Sbjct: 207 RLWNGGRAIEHAAQLASDPLAYEFPLPLAQQRNCNFSFAGIKNNSFRAIRA-RERAERTP 265 Query: 219 ---------DLAYSFQETAFAALVEVTERAVAH----------TEKDEVVLVGGVAANNR 259 D + L+ T+RA+ + +V+ GGVA N+ Sbjct: 266 PDGVISNYGDFCAGLLRSVSRHLMHRTQRAIEYCLLPHRQLFGDTPPTLVMSGGVANNDA 325 Query: 260 LREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGL 295 + + + G + F P C DNG MIA+ G+ Sbjct: 326 IYANIEHLAAQYGCRSFRPSKRYCSDNGVMIAWHGV 361 >pir||E71801 probable o-sialoglycoprotein endopeptidase - Helicobacter pylori (strain J99) >gi|4156114|gb|AAD07065.1| (AE001570) putative O-SIALOGLYCOPROTEIN ENDOPEPTIDASE [Helicobacter pylori J99] Length = 340 Score = 94.8 bits (232), Expect = 1e-18 Identities = 78/294 (26%), Positives = 127/294 (42%), Gaps = 15/294 (5%) Query: 36 GGIHPKEAAEHHARLMKPLLRKALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALA 95 GG+ P+ A+ HA + LL + I IA + PGL L A+AL+ Sbjct: 40 GGVVPEIASRLHAENLPLLLERVKISLNKDFSKIKAIAITNQPGLSVTLIEGLMMAKALS 99 Query: 96 VKYRKPIVGVNHCIAHVE--ITKMFGVKDPVG-LYVSGGNTQVL-ALEGGRYRVFGETLD 151 + P++ +H HV + P+ L VSGG++ +L A + ++ +LD Sbjct: 100 LSLNLPLILEDHLRGHVYSLFINEKQTRMPLSVLLVSGGHSLILEARDYEDIKIVATSLD 159 Query: 152 IGIGNAIDVFARELGLGFPGGPKVEKLA---EKGEKYIELPYAVK---GMDLSFSGLLTE 205 G + D ++ L LG+PGGP VEKLA + + P +K + SFSGL Sbjct: 160 DSFGESFDKVSKMLDLGYPGGPIVEKLALDYAHPNEPLMFPIPLKNSPNLAFSFSGLKNA 219 Query: 206 AIRKYRSGKYRVED-----LAYSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRL 260 + + + D + Y FQ A L++ T+R +VGG + N L Sbjct: 220 VRLEVEKNAHNLNDEVKQKIGYHFQSAAIEHLIQQTKRYFKIKRPKIFGIVGGASQNLAL 279 Query: 261 REMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGLRMYKAGISFRLEETIVKQK 314 R+ + + + + P + C DN AMI + L Y+ LE+ + + Sbjct: 280 RKAFEDLCAEFDCELVLAPLEFCSDNAAMIGRSSLEAYQKKRFIPLEKADISPR 333 >gb|AAD00282.1| (U78601) putative sialoglycoprotease protein [Streptococcus mutans] Length = 155 Score = 94.0 bits (230), Expect = 2e-18 Identities = 52/143 (36%), Positives = 82/143 (56%), Gaps = 3/143 (2%) Query: 36 GGIHPKEAAEHHARLMKPLLRKALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALA 95 GG+ PK A+ HH ++ ++ AL EAG++ D+ +A + GPGL AL V AA+A A Sbjct: 13 GGVVPKLASRHHVEVITLCIQDALQEAGITAGDLSAVAVTYGPGLVGALLVGMAAAKAFA 72 Query: 96 VKYRKPIVGVNHCIAHVEITKMFG-VKDP-VGLYVSGGNTQVLALEG-GRYRVFGETLDI 152 P++ VNH H+ + ++ P + L VSGG+T+++ + G YR+ GET D Sbjct: 73 WANHLPLIPVNHMAGHLMAAQSIADLQYPLLALLVSGGHTELVYVAAPGDYRIVGETRDN 132 Query: 153 GIGNAIDVFARELGLGFPGGPKV 175 +G A D R +GL +P G ++ Sbjct: 133 AVGEAYDKVGRVMGLTYPAGKEI 155 >sp|P55996|GCP_HELPY PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROTEASE) >gi|7444710|pir||H64717 sialoglycoproteinase gcp (EC 3.4.-.-) - Helicobacter pylori (strain 26695) >gi|2314767|gb|AAD08622.1| (AE000655) sialoglycoprotease (gcp) [Helicobacter pylori 26695] Length = 340 Score = 92.8 bits (227), Expect = 5e-18 Identities = 80/288 (27%), Positives = 123/288 (41%), Gaps = 33/288 (11%) Query: 36 GGIHPKEAAEHHARLMKPLLRKALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALA 95 GG+ P+ A+ HA + LL + I IA + PGL L A+AL+ Sbjct: 40 GGVVPELASRLHAENLPLLLERIKISLNKDFSKIKAIAITNQPGLSVTLIEGLMMAKALS 99 Query: 96 VKYRKPIVGVNHCIAHVE---ITKMFGVKDPVGLYVSGGNTQVL-ALEGGRYRVFGETLD 151 + P++ +H HV I + L VSGG++ +L A + ++ +LD Sbjct: 100 LSLNLPLILEDHLRGHVYSLFINEKQTCMPLSVLLVSGGHSLILEARDYENIKIVATSLD 159 Query: 152 IGIGNAIDVFARELGLGFPGGPKVEKLA---EKGEKYIELPYAVK---GMDLSFSGL--- 202 G + D ++ L LG+PGGP VEKLA + + P +K + SFSGL Sbjct: 160 DSFGESFDKVSKMLDLGYPGGPIVEKLALDYRHPNEPLMFPIPLKNSPNLAFSFSGLKNA 219 Query: 203 -----------LTEAIRKYRSGKYRVEDLAYSFQETAFAALVEVTERAVAHTEKDEVVLV 251 L EAI+ + + Y FQ A L++ T+R +V Sbjct: 220 VRLEVEKNAPNLNEAIK---------QKIGYHFQSAAIEHLIQQTKRYFKIKRPKIFGIV 270 Query: 252 GGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGLRMYK 299 GG + N LR+ + + K + P + C DN AMI + L Y+ Sbjct: 271 GGASQNLALRKAFENLCDAFDCKLVLAPLEFCSDNAAMIGRSSLEAYQ 318 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.320 0.140 0.398 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 116600517 Number of Sequences: 2977 Number of extensions: 4927131 Number of successful extensions: 11084 Number of sequences better than 1.0e-10: 55 Number of HSP's better than 0.0 without gapping: 25 Number of HSP's successfully gapped in prelim test: 30 Number of HSP's that attempted gapping in prelim test: 10892 Number of HSP's gapped (non-prelim): 57 length of query: 324 length of database: 189,106,746 effective HSP length: 56 effective length of query: 268 effective length of database: 155,591,474 effective search space: 41698515032 effective search space used: 41698515032 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.8 bits) S2: 165 (68.7 bits)