BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB1159 (gcp) DE:O-sialoglycoprotein endopeptidase (gcp)
         (324 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||F75029 o-sialoglycoprotein endopeptidase (gcp) PAB1159 - Py...   644  0.0
sp|O57716|GCP_PYRHO PUTATIVE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (...   611  e-174
gi|11498712 O-sialoglycoprotein endopeptidase (gcp) [Archaeoglob...   394  e-109
sp|O27476|GCP_METTH PUTATIVE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (...   386  e-106
pir||A64441 O-sialoglycoprotein endopeptidase (EC 3.4.24.57) hom...   364  e-100
sp|Q58530|GCP_METJA PUTATIVE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (...   364  e-100
emb|CAC11469.1| (AL445064) O-sialoglycoprotein endopeptidase rel...   353  2e-96
pir||T04567 O-sialoglycoprotein endopeptidase homolog T12H17.110...   316  2e-85
gb|AAF49481.1| (AE003527) CG4933 gene product [Drosophila melano...   307  9e-83
gi|8923380 hypothetical protein FLJ20411 [Homo sapiens] >gi|1143...   306  3e-82
pir||T39567 glycoprotein endopeptidase-like protein - fission ye...   303  2e-81
pir||H72714 probable O-sialoglycoprotein endopeptidase APE1135 -...   290  1e-77
dbj|BAA82123.1| (AB023065) O-sialoglycoprotease [Rattus norvegicus]   283  2e-75
gi|6322891 probable calcium-binding protein; Ykr038cp [Saccharom...   263  2e-69
gb|AAG20204.1| (AE005096) O-sialoglycoprotein endopeptidase homo...   244  1e-63
gb|AAK40758.1| O-sialoglycoprotein endopeptidase [Sulfolobus sol...   215  7e-55
sp|P43764|GCP_HAEIN PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (...   192  6e-48
sp|P36174|YHSH_HALMA HYPOTHETICAL PROTEIN IN HSH 3'REGION (ORFX)...   190  1e-47
sp|O66986|GCP_AQUAE PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (...   190  2e-47
sp|O05518|GCP_BACSU PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (...   188  7e-47
pir||G72411 hypothetical protein TM0145 - Thermotoga maritima (s...   182  5e-45
pir||QQECR6 O-sialoglycoprotein endopeptidase (EC 3.4.24.57) - E...   177  1e-43
sp|P05852|GCP_ECOLI PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (...   175  5e-43
sp|O86793|GCP_STRCO PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (...   175  5e-43
pir||H83572 O-sialoglycoprotein endopeptidase PA0580 [imported] ...   173  2e-42
dbj|BAB04267.1| (AP001508) glycoprotein endopeptidase [Bacillus ...   173  2e-42
pir||D82807 O-sialoglycoprotein endopeptidase XF0435 [imported] ...   172  4e-42
pir||C81986 probable O-sialoglycoprotein endopeptidase (EC 3.4.2...   169  4e-41
sp|P36175|GCP_PASHA O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROT...   169  5e-41
pir||C81040 O-sialoglycoprotein endopeptidase NMB1802 [imported]...   168  6e-41
gb|AAF32396.1|AF224466_3 (AF224466) sialylglycoprotease [Haemoph...   166  4e-40
sp|P74034|GCP_SYNY3 PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (...   164  1e-39
gb|AAB82636.1| (AC002387) putative O-sialoglycoprotein endopepti...   155  6e-37
sp|O51710|GCP_BORBU PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (...   152  4e-36
pir||A71545 probable o-sialoglycoprotein endopeptidase - Chlamyd...   149  5e-35
pir||H72106 o-sialoglycoprotein endopeptidase - Chlamydophila pn...   148  6e-35
sp|Q50709|GCP_MYCTU PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (...   143  3e-33
sp|P57166|GCP_BUCAI PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (...   143  3e-33
gb|AAF73560.1| (AE002315) O-sialoglycoprotein endopeptidase [Chl...   143  4e-33
sp|Q9ZEA8|GCP_RICPR PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (...   141  1e-32
sp|P37969|GCP_MYCLE PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (...   133  2e-30
sp|O83686|GCP_TREPA PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (...   125  5e-28
gi|6320099 similar to H.influenzae sialoglycoprotease; Qri7p [Sa...   124  1e-27
sp|P75055|GCP_MYCPN PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (...   123  3e-27
sp|P47292|GCP_MYCGE PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (...   115  1e-24
pir||S72996 probable glycoproteinase u229e - Mycobacterium lepra...   112  6e-24
gi|11641265 putative sialoglycoprotease type 2 [Homo sapiens] >g...   110  2e-23
pir||T40899 probable proteinase - fission yeast (Schizosaccharom...   109  6e-23
pir||T18825 hypothetical protein C01G10.10 - Caenorhabditis eleg...   103  3e-21
pir||H82894 sialoglycoproteinase UU411 [imported] - Ureaplasma u...   101  1e-20
pir||E81278 probable glycoproteinase Cj1344c [imported] - Campyl...    99  6e-20
gb|AAF49008.1| (AE003513) CG14231 gene product [Drosophila melan...    97  2e-19
pir||E71801 probable o-sialoglycoprotein endopeptidase - Helicob...    95  1e-18
gb|AAD00282.1| (U78601) putative sialoglycoprotease protein [Str...    94  2e-18
sp|P55996|GCP_HELPY PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (...    93  5e-18

>pir||F75029 o-sialoglycoprotein endopeptidase (gcp) PAB1159 - Pyrococcus abyssi
           (strain Orsay) >gi|5459190|emb|CAB50676.1| (AJ248288)
           O-sialoglycoprotein endopeptidase (gcp) [Pyrococcus
           abyssi]
           Length = 324
           
 Score =  644 bits (1642), Expect = 0.0
 Identities = 324/324 (100%), Positives = 324/324 (100%)

Query: 1   MLALGIEGTAHTLGIGIVSEDKVLANVFDTLTTEKGGIHPKEAAEHHARLMKPLLRKALS 60
           MLALGIEGTAHTLGIGIVSEDKVLANVFDTLTTEKGGIHPKEAAEHHARLMKPLLRKALS
Sbjct: 1   MLALGIEGTAHTLGIGIVSEDKVLANVFDTLTTEKGGIHPKEAAEHHARLMKPLLRKALS 60

Query: 61  EAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKMFGV 120
           EAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKMFGV
Sbjct: 61  EAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKMFGV 120

Query: 121 KDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGPKVEKLAE 180
           KDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGPKVEKLAE
Sbjct: 121 KDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGPKVEKLAE 180

Query: 181 KGEKYIELPYAVKGMDLSFSGLLTEAIRKYRSGKYRVEDLAYSFQETAFAALVEVTERAV 240
           KGEKYIELPYAVKGMDLSFSGLLTEAIRKYRSGKYRVEDLAYSFQETAFAALVEVTERAV
Sbjct: 181 KGEKYIELPYAVKGMDLSFSGLLTEAIRKYRSGKYRVEDLAYSFQETAFAALVEVTERAV 240

Query: 241 AHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGLRMYKA 300
           AHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGLRMYKA
Sbjct: 241 AHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGLRMYKA 300

Query: 301 GISFRLEETIVKQKFRTDEVEIVW 324
           GISFRLEETIVKQKFRTDEVEIVW
Sbjct: 301 GISFRLEETIVKQKFRTDEVEIVW 324


>sp|O57716|GCP_PYRHO PUTATIVE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROTEASE)
           >gi|7444716|pir||C71215 O-sialoglycoprotein
           endopeptidase homolog PH1987 - Pyrococcus horikoshii
           >gi|3258431|dbj|BAA31114.1| (AP000007) 324aa long
           hypothetical O-sialoglycoprotein endopeptidase
           [Pyrococcus horikoshii]
           Length = 324
           
 Score =  611 bits (1558), Expect = e-174
 Identities = 301/324 (92%), Positives = 316/324 (96%)

Query: 1   MLALGIEGTAHTLGIGIVSEDKVLANVFDTLTTEKGGIHPKEAAEHHARLMKPLLRKALS 60
           MLALGIEGTAHTLGIGIVSE KVLANVFDTLTTEKGGIHPKEAAEHHARLMKPLL+KAL 
Sbjct: 1   MLALGIEGTAHTLGIGIVSEKKVLANVFDTLTTEKGGIHPKEAAEHHARLMKPLLKKALE 60

Query: 61  EAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKMFGV 120
           +AG+S+DDIDVIAFSQGPGLGPALRVVATAARALA++Y KPIVGVNHCIAHVEITKMFG+
Sbjct: 61  KAGISMDDIDVIAFSQGPGLGPALRVVATAARALAIRYNKPIVGVNHCIAHVEITKMFGI 120

Query: 121 KDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGPKVEKLAE 180
           KDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGPK+EKLAE
Sbjct: 121 KDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGPKLEKLAE 180

Query: 181 KGEKYIELPYAVKGMDLSFSGLLTEAIRKYRSGKYRVEDLAYSFQETAFAALVEVTERAV 240
           KG+ YI+LPYAVKGMDLSFSGLLTEAIRKYRSGK+RVEDLAYSFQETAFAALVEVTERA+
Sbjct: 181 KGKNYIDLPYAVKGMDLSFSGLLTEAIRKYRSGKFRVEDLAYSFQETAFAALVEVTERAL 240

Query: 241 AHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGLRMYKA 300
           AHTEK EVVLVGGVAANNRLREML+IM EDRG+KFFVPPYDLCRDNGAMIAYTGLRMYKA
Sbjct: 241 AHTEKKEVVLVGGVAANNRLREMLKIMAEDRGVKFFVPPYDLCRDNGAMIAYTGLRMYKA 300

Query: 301 GISFRLEETIVKQKFRTDEVEIVW 324
           GISF LE+TIVKQKFRTDEVEI W
Sbjct: 301 GISFPLEKTIVKQKFRTDEVEITW 324


>gi|11498712 O-sialoglycoprotein endopeptidase (gcp) [Archaeoglobus fulgidus]
           >gi|7444721|pir||G69388 O-sialoglycoprotein
           endopeptidase homolog - Archaeoglobus fulgidus
           >gi|2649475|gb|AAB90129.1| (AE001027)
           O-sialoglycoprotein endopeptidase (gcp) [Archaeoglobus
           fulgidus]
           Length = 323
           
 Score =  394 bits (1001), Expect = e-109
 Identities = 199/325 (61%), Positives = 251/325 (77%), Gaps = 4/325 (1%)

Query: 1   MLALGIEGTAHTLGIGIVSEDKVLANVFDTLTTEKGGIHPKEAAEHHARLMKPLLRKALS 60
           M+ALGIEGTA +L IG+V E+ V+A   D    ++GGIHP+EA++HH+  +  LL +   
Sbjct: 1   MIALGIEGTAWSLSIGVVDEEGVIALENDPYIPKEGGIHPREASQHHSERLPSLLSRVFE 60

Query: 61  EAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITK-MFG 119
           +  V  + IDV+AFSQGPG+GP LRVVATAAR LA+K  KP+VGVNHC+AHVE+ +   G
Sbjct: 61  K--VDKNSIDVVAFSQGPGMGPCLRVVATAARLLAIKLEKPLVGVNHCLAHVEVGRWQTG 118

Query: 120 VKDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGPKVEKLA 179
            + PV LYVSGGN+QV+A  G RYRVFGETLDIGIGNA+D  AR +GL  PGGPK+E+LA
Sbjct: 119 ARKPVSLYVSGGNSQVIARRGNRYRVFGETLDIGIGNALDKLARHMGLKHPGGPKIEELA 178

Query: 180 EKGEKYIELPYAVKGMDLSFSGLLTEAIRKYRSGKYRVEDLAYSFQETAFAALVEVTERA 239
           +KG+KY  LPY VKGMD SFSG++T A R + SG  R+ED+A+SFQETAFA L EVTERA
Sbjct: 179 KKGQKYHFLPYVVKGMDFSFSGMVTAAQRLFDSG-VRMEDVAFSFQETAFAMLTEVTERA 237

Query: 240 VAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGLRMYK 299
           +A+ + +EV+LVGGVAAN RL+EMLRIM EDRG KF+VPP +L  DNGAMIAYTGL MYK
Sbjct: 238 LAYLDLNEVLLVGGVAANKRLQEMLRIMCEDRGAKFYVPPKELAGDNGAMIAYTGLLMYK 297

Query: 300 AGISFRLEETIVKQKFRTDEVEIVW 324
            G    +E++ V+  FR ++VE+ W
Sbjct: 298 HGHQTPVEKSYVRPDFRIEDVEVNW 322


>sp|O27476|GCP_METTH PUTATIVE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROTEASE)
           >gi|7482768|pir||H69056 O-sialoglycoprotein
           endopeptidase - Methanobacterium thermoautotrophicum
           (strain Delta H) >gi|2622538|gb|AAB85902.1| (AE000904)
           O-sialoglycoprotein endopeptidase [Methanobacterium
           thermoautotrophicum]
           Length = 534
           
 Score =  386 bits (981), Expect = e-106
 Identities = 199/326 (61%), Positives = 246/326 (75%), Gaps = 3/326 (0%)

Query: 1   MLALGIEGTAHTLGIGIVSE-DKVLANVFDTLTTEKGGIHPKEAAEHHARLMKPLLRKAL 59
           ML LGIEGTA   G+GIV E   VL+     L  EKGGIHP+EAAEHHA+ +  L+ +A 
Sbjct: 1   MLCLGIEGTAEKTGVGIVDEAGNVLSLRGKPLIPEKGGIHPREAAEHHAKWIPRLIAEAC 60

Query: 60  SEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKMF- 118
            +AGV L +I +I+FS+GPGLGPALR VATAAR LA+    PIVGVNHCI H+EI ++  
Sbjct: 61  RDAGVELGEIGLISFSRGPGLGPALRTVATAARTLALSLDVPIVGVNHCIGHIEIGRLTT 120

Query: 119 GVKDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGPKVEKL 178
           G  DPV LYVSGGNTQV+A   GRYRVFGETLDI +GN +D FARE GLG PGGP +E+L
Sbjct: 121 GASDPVSLYVSGGNTQVIAFNEGRYRVFGETLDIAVGNMLDQFARESGLGHPGGPVIEQL 180

Query: 179 AEKGEKYIELPYAVKGMDLSFSGLLTEAIRKYRSGKYRVEDLAYSFQETAFAALVEVTER 238
           A K  +YIELPY+VKGMD+SFSGLLT A+RK  +G   +EDLAYS QETAF+ LVEVTER
Sbjct: 181 ALKASEYIELPYSVKGMDISFSGLLTAALRKMEAGA-SLEDLAYSIQETAFSMLVEVTER 239

Query: 239 AVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGLRMY 298
           A+A+TEK++V+L GGVA N RLR+MLR M ++  ++F +PP + C DNGAMIA+ G  +Y
Sbjct: 240 ALAYTEKNQVLLCGGVAVNRRLRDMLREMCQEHHVEFHMPPPEYCGDNGAMIAWLGQLVY 299

Query: 299 KAGISFRLEETIVKQKFRTDEVEIVW 324
           K      LE+T V Q++RTDEV++ W
Sbjct: 300 KYRGPDALEDTTVVQRYRTDEVDVPW 325


>pir||A64441 O-sialoglycoprotein endopeptidase (EC 3.4.24.57) homolog -
           Methanococcus jannaschii
           Length = 539
           
 Score =  364 bits (924), Expect = e-100
 Identities = 185/326 (56%), Positives = 240/326 (72%), Gaps = 5/326 (1%)

Query: 1   MLALGIEGTAHTLGIGIVSED-KVLANVFDTLTTEKGGIHPKEAAEHHARLMKPLLRKAL 59
           M+ LG+EGTA   G+GIV+ D +VL N        K GI+P+EAA+HHA     L+++A 
Sbjct: 5   MICLGLEGTAEKTGVGIVTSDGEVLFNKTIMYKPPKQGINPREAADHHAETFPKLIKEAF 64

Query: 60  SEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKMFG 119
               V  ++ID+IAFSQGPGLGP+LRV AT AR L++  +KPI+GVNHCIAH+EI K+  
Sbjct: 65  EV--VDKNEIDLIAFSQGPGLGPSLRVTATVARTLSLTLKKPIIGVNHCIAHIEIGKLTT 122

Query: 120 -VKDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGPKVEKL 178
             +DP+ LYVSGGNTQV+A    +YRVFGETLDI +GN +D FAR + L  PGGP +E+L
Sbjct: 123 EAEDPLTLYVSGGNTQVIAYVSKKYRVFGETLDIAVGNCLDQFARYVNLPHPGGPYIEEL 182

Query: 179 AEKGEKYIELPYAVKGMDLSFSGLLTEAIRKYRSGKYRVEDLAYSFQETAFAALVEVTER 238
           A KG+K ++LPY VKGMD++FSGLLT A+R Y +G+ R+ED+ YS QE AF+ L E+TER
Sbjct: 183 ARKGKKLVDLPYTVKGMDIAFSGLLTAAMRAYDAGE-RLEDICYSLQEYAFSMLTEITER 241

Query: 239 AVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGLRMY 298
           A+AHT K EV+LVGGVAANNRLREML+ M E + + F+VPP + C DNGAMIA+ GL M+
Sbjct: 242 ALAHTNKGEVMLVGGVAANNRLREMLKAMCEGQNVDFYVPPKEFCGDNGAMIAWLGLLMH 301

Query: 299 KAGISFRLEETIVKQKFRTDEVEIVW 324
           K G    L+ET +   +RTD VE+ W
Sbjct: 302 KNGRWMSLDETKIIPNYRTDMVEVNW 327


>sp|Q58530|GCP_METJA PUTATIVE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROTEASE)
           >gi|2826367|gb|AAB99132.1| (U67555) O-sialoglycoprotein
           endopeptidase (gcp) [Methanococcus jannaschii]
           Length = 535
           
 Score =  364 bits (924), Expect = e-100
 Identities = 185/326 (56%), Positives = 240/326 (72%), Gaps = 5/326 (1%)

Query: 1   MLALGIEGTAHTLGIGIVSED-KVLANVFDTLTTEKGGIHPKEAAEHHARLMKPLLRKAL 59
           M+ LG+EGTA   G+GIV+ D +VL N        K GI+P+EAA+HHA     L+++A 
Sbjct: 1   MICLGLEGTAEKTGVGIVTSDGEVLFNKTIMYKPPKQGINPREAADHHAETFPKLIKEAF 60

Query: 60  SEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKMFG 119
               V  ++ID+IAFSQGPGLGP+LRV AT AR L++  +KPI+GVNHCIAH+EI K+  
Sbjct: 61  EV--VDKNEIDLIAFSQGPGLGPSLRVTATVARTLSLTLKKPIIGVNHCIAHIEIGKLTT 118

Query: 120 -VKDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGPKVEKL 178
             +DP+ LYVSGGNTQV+A    +YRVFGETLDI +GN +D FAR + L  PGGP +E+L
Sbjct: 119 EAEDPLTLYVSGGNTQVIAYVSKKYRVFGETLDIAVGNCLDQFARYVNLPHPGGPYIEEL 178

Query: 179 AEKGEKYIELPYAVKGMDLSFSGLLTEAIRKYRSGKYRVEDLAYSFQETAFAALVEVTER 238
           A KG+K ++LPY VKGMD++FSGLLT A+R Y +G+ R+ED+ YS QE AF+ L E+TER
Sbjct: 179 ARKGKKLVDLPYTVKGMDIAFSGLLTAAMRAYDAGE-RLEDICYSLQEYAFSMLTEITER 237

Query: 239 AVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGLRMY 298
           A+AHT K EV+LVGGVAANNRLREML+ M E + + F+VPP + C DNGAMIA+ GL M+
Sbjct: 238 ALAHTNKGEVMLVGGVAANNRLREMLKAMCEGQNVDFYVPPKEFCGDNGAMIAWLGLLMH 297

Query: 299 KAGISFRLEETIVKQKFRTDEVEIVW 324
           K G    L+ET +   +RTD VE+ W
Sbjct: 298 KNGRWMSLDETKIIPNYRTDMVEVNW 323


>emb|CAC11469.1| (AL445064) O-sialoglycoprotein endopeptidase related protein
           [Thermoplasma acidophilum]
           Length = 529
           
 Score =  353 bits (895), Expect = 2e-96
 Identities = 174/325 (53%), Positives = 234/325 (71%), Gaps = 2/325 (0%)

Query: 1   MLALGIEGTAHTLGIGIVSEDKVLANVFDTLTTEKGGIHPKEAAEHHARLMKPLLRKALS 60
           M+ LG+EGTAHT+  GI+ E ++LA        + GGI P +AA HH+ ++  ++ +AL 
Sbjct: 1   MIVLGLEGTAHTISCGIIDESRILAMESSMYRPKTGGIRPLDAAVHHSEVIDTVISRALE 60

Query: 61  EAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEI-TKMFG 119
           +A +S+ DID+I FS GPGL P+LRV ATAAR ++V   KPI+GVNH + H+EI  ++ G
Sbjct: 61  KAKISIHDIDLIGFSMGPGLAPSLRVTATAARTISVLTGKPIIGVNHPLGHIEIGRRVTG 120

Query: 120 VKDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGPKVEKLA 179
             DPV LYVSGGNTQV+A   GRYRV GETLDIGIGN ID FARE G+ FPGGP++EKLA
Sbjct: 121 AIDPVMLYVSGGNTQVIAHVNGRYRVLGETLDIGIGNMIDKFAREAGIPFPGGPEIEKLA 180

Query: 180 EKGEKYIELPYAVKGMDLSFSGLLTEAIRKYRSGKYRVEDLAYSFQETAFAALVEVTERA 239
            KG K ++LPY+VKGMD +FSG+LT A++  ++G+  +ED++YS QETAFA LVEV ERA
Sbjct: 181 MKGTKLLDLPYSVKGMDTAFSGILTAALQYLKTGQ-AIEDISYSIQETAFAMLVEVLERA 239

Query: 240 VAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGLRMYK 299
           +  + KDE+++ GGVA N RLR+M+  M  + GI+ ++   + C DNG MIA   L MYK
Sbjct: 240 LYVSGKDEILMAGGVALNRRLRDMVTNMAREAGIRSYLTDREYCMDNGIMIAQAALLMYK 299

Query: 300 AGISFRLEETIVKQKFRTDEVEIVW 324
           +G+   +EET V  +FR DEV+  W
Sbjct: 300 SGVRMSVEETAVNPRFRIDEVDAPW 324


>pir||T04567 O-sialoglycoprotein endopeptidase homolog T12H17.110 - Arabidopsis
           thaliana >gi|2827549|emb|CAA16557.1| (AL021635)
           glycoprotein endopeptidase - like protein [Arabidopsis
           thaliana] >gi|7269118|emb|CAB79227.1| (AL161557)
           glycoprotein endopeptidase-like protein [Arabidopsis
           thaliana]
           Length = 353
           
 Score =  316 bits (802), Expect = 2e-85
 Identities = 167/333 (50%), Positives = 225/333 (67%), Gaps = 9/333 (2%)

Query: 1   MLALGIEGTAHTLGIGIVSED-KVLANVFDTLTTEKG-GIHPKEAAEHHARLMKPLLRKA 58
           M+A+G EG+A+ +G+GIV+ D  +LAN   T  T  G G  P+E A HH   + PL++ A
Sbjct: 5   MIAIGFEGSANKIGVGIVTLDGTILANPRHTYITPPGHGFLPRETAHHHLDHVLPLVKSA 64

Query: 59  LSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKMF 118
           L  + V+ ++ID I +++GPG+G  L+V A   R L+  ++KPIV VNHC+AH+E+ ++ 
Sbjct: 65  LETSQVTPEEIDCICYTKGPGMGAPLQVSAIVVRVLSQLWKKPIVAVNHCVAHIEMGRVV 124

Query: 119 -GVKDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGP--KV 175
            G  DPV LYVSGGNTQV+A   GRYR+FGET+DI +GN +D FAR L L     P   +
Sbjct: 125 TGADDPVVLYVSGGNTQVIAYSEGRYRIFGETIDIAVGNCLDRFARVLKLSNDPSPGYNI 184

Query: 176 EKLAEKGEKYIELPYAVKGMDLSFSGLL----TEAIRKYRSGKYRVEDLAYSFQETAFAA 231
           E+LA+KGE +I+LPYAVKGMD+SFSG+L    T A  K ++ +    DL YS QET FA 
Sbjct: 185 EQLAKKGENFIDLPYAVKGMDVSFSGILSYIETTAEEKLKNNECTPADLCYSLQETVFAM 244

Query: 232 LVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIA 291
           LVE+TERA+AH +K +V++VGGV  N RL+EM+R M  +R  K F      C DNGAMIA
Sbjct: 245 LVEITERAMAHCDKKDVLIVGGVGCNERLQEMMRTMCSERDGKLFATDDRYCIDNGAMIA 304

Query: 292 YTGLRMYKAGISFRLEETIVKQKFRTDEVEIVW 324
           YTGL  +  GI   +E++   Q+FRTDEV  VW
Sbjct: 305 YTGLLAFVNGIETPIEDSTFTQRFRTDEVHAVW 337


>gb|AAF49481.1| (AE003527) CG4933 gene product [Drosophila melanogaster]
           Length = 347
           
 Score =  307 bits (779), Expect = 9e-83
 Identities = 163/341 (47%), Positives = 218/341 (63%), Gaps = 19/341 (5%)

Query: 3   ALGIEGTAHTLGIGIVSEDKVLANVFDTLTTEKG-GIHPKEAAEHHARLMKPLLRKALSE 61
           ALGIEG+A+ +GIGI+ + KVLANV  T  T  G G  PKE A+HH   +  L+  +L E
Sbjct: 4   ALGIEGSANKIGIGIIRDGKVLANVRRTYITPPGEGFLPKETAKHHREAILGLVESSLKE 63

Query: 62  AGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKMF-GV 120
           A +   D+DVI +++GPG+ P L V A  AR L++ +  P++GVNHCI H+E+ ++  G 
Sbjct: 64  AQLKSSDLDVICYTKGPGMAPPLLVGAIVARTLSLLWNIPLLGVNHCIGHIEMGRLITGA 123

Query: 121 KDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGP--KVEKL 178
           ++P  LYVSGGNTQV+A    RYR+FGET+DI +GN +D FAR + L     P   +E+L
Sbjct: 124 QNPTVLYVSGGNTQVIAYSNKRYRIFGETIDIAVGNCLDRFARIIKLSNDPSPGYNIEQL 183

Query: 179 AEKGEKYIELPYAVKGMDLSFSGLLTEAIRKYRSGK---------------YRVEDLAYS 223
           A+   +YI+LPY VKGMD+SFSG+L+        GK               Y   DL YS
Sbjct: 184 AKSSNRYIKLPYVVKGMDVSFSGILSYIEDLAEPGKRQNKRKKPQEEEVNNYSQADLCYS 243

Query: 224 FQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLC 283
            QET FA LVE+TERA+AH   +EV++VGGV  N RL+EM+RIM E+RG K F      C
Sbjct: 244 LQETIFAMLVEITERAMAHCGSNEVLIVGGVGCNERLQEMMRIMCEERGGKLFATDERYC 303

Query: 284 RDNGAMIAYTGLRMYKAGISFRLEETIVKQKFRTDEVEIVW 324
            DNG MIA+ G  M+++G     EE+ V Q+FRTDEV + W
Sbjct: 304 IDNGLMIAHAGAEMFRSGTRMPFEESYVTQRFRTDEVLVSW 344


>gi|8923380 hypothetical protein FLJ20411 [Homo sapiens]
           >gi|11437426|ref|XP_007489.1| hypothetical protein
           FLJ20411 [Homo sapiens] >gi|6850969|emb|CAB71031.1|
           (AJ271669) putative sialoglycoprotease [Homo sapiens]
           >gi|7020492|dbj|BAA91150.1| (AK000418) unnamed protein
           product [Homo sapiens]
           Length = 335
           
 Score =  306 bits (775), Expect = 3e-82
 Identities = 158/329 (48%), Positives = 219/329 (66%), Gaps = 8/329 (2%)

Query: 4   LGIEGTAHTLGIGIVSEDKVLANVFDTLTTEKG-GIHPKEAAEHHARLMKPLLRKALSEA 62
           LG EG+A+ +G+G+V + KVLAN   T  T  G G  P + A HH  ++  LL++AL+E+
Sbjct: 5   LGFEGSANKIGVGVVRDGKVLANPRRTYVTPPGTGFLPGDTARHHRAVILDLLQEALTES 64

Query: 63  GVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKMF-GVK 121
           G++  DID IA+++GPG+G  L  VA  AR +A  + KP+VGVNHCI H+E+ ++  G  
Sbjct: 65  GLTSQDIDCIAYTKGPGMGAPLVSVAVVARTVAQLWNKPLVGVNHCIGHIEMGRLITGAT 124

Query: 122 DPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGP--KVEKLA 179
            P  LYVSGGNTQV+A    RYR+FGET+DI +GN +D FAR L +     P   +E++A
Sbjct: 125 SPTVLYVSGGNTQVIAYSEHRYRIFGETIDIAVGNCLDRFARVLKISNDPSPGYNIEQMA 184

Query: 180 EKGEKYIELPYAVKGMDLSFSGLLT----EAIRKYRSGKYRVEDLAYSFQETAFAALVEV 235
           ++G+K +ELPY VKGMD+SFSG+L+     A R   +G+   EDL +S QET FA LVE+
Sbjct: 185 KRGKKLVELPYTVKGMDVSFSGILSFIEDVAHRMLATGECTPEDLCFSLQETVFAMLVEI 244

Query: 236 TERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGL 295
           TERA+AH    E ++VGGV  N RL+EM+  M ++RG + F      C DNGAMIA  G 
Sbjct: 245 TERAMAHCGSQEALIVGGVGCNVRLQEMMATMCQERGARLFATDERFCIDNGAMIAQAGW 304

Query: 296 RMYKAGISFRLEETIVKQKFRTDEVEIVW 324
            M++AG    L ++ V Q++RTDEVE+ W
Sbjct: 305 EMFRAGHRTPLSDSGVTQRYRTDEVEVTW 333


>pir||T39567 glycoprotein endopeptidase-like protein - fission yeast
           (Schizosaccharomyces pombe) >gi|4481949|emb|CAB38507.1|
           (AL035637) glycoprotein endopeptidase-like protein.
           [Schizosaccharomyces pombe]
           Length = 346
           
 Score =  303 bits (768), Expect = 2e-81
 Identities = 162/340 (47%), Positives = 219/340 (63%), Gaps = 16/340 (4%)

Query: 1   MLALGIEGTAHTLGIGIVSED-----KVLANVFDTLTTEKG-GIHPKEAAEHHARLMKPL 54
           ++ALG+EG+A+ LG+GI+  D     K+LANV  T  T  G G  P + A+HH   + PL
Sbjct: 5   LIALGLEGSANKLGVGIILHDTNGSAKILANVRHTYITPPGQGFLPSDTAKHHRAWIIPL 64

Query: 55  LRKALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEI 114
           +++A +EA +S  DID I F++GPG+G  L  VA  AR L++ ++KP+V VNHCI H+E+
Sbjct: 65  IKQAFAEAKISFKDIDCICFTKGPGIGAPLNSVALCARMLSLIHKKPLVAVNHCIGHIEM 124

Query: 115 TK-MFGVKDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGP 173
            + + G ++PV LYVSGGNTQV+A    +YR+FGETLDI IGN +D FAR +GL     P
Sbjct: 125 GREITGAQNPVVLYVSGGNTQVIAYSEKKYRIFGETLDIAIGNCLDRFARIIGLSNAPSP 184

Query: 174 --KVEKLAEKGEKYIELPYAVKGMDLSFSGLL-------TEAIRKYRSGKYRVEDLAYSF 224
              + + A+KG+++IELPY VKGMD SFSGLL       TE +          +DL YS 
Sbjct: 185 GYNIMQEAKKGKRFIELPYTVKGMDCSFSGLLSGVEAAATELLDPKNPSSVTKQDLCYSL 244

Query: 225 QETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCR 284
           QET FA LVE+TERA+AH   D V++VGGV  N RL++M+  M+ DRG   F      C 
Sbjct: 245 QETGFAMLVEITERAMAHIRADSVLIVGGVGCNERLQQMMAEMSSDRGADVFSTDERFCI 304

Query: 285 DNGAMIAYTGLRMYKAGISFRLEETIVKQKFRTDEVEIVW 324
           DNG MIA  GL  YK G    + E+ + Q++RTD+V I W
Sbjct: 305 DNGIMIAQAGLLAYKTGDRCAVAESTITQRYRTDDVYISW 344


>pir||H72714 probable O-sialoglycoprotein endopeptidase APE1135 - Aeropyrum
           pernix (strain K1) >gi|5104805|dbj|BAA80120.1|
           (AP000060) 349aa long hypothetical O-sialoglycoprotein
           endopeptidase [Aeropyrum pernix]
           Length = 349
           
 Score =  290 bits (735), Expect = 1e-77
 Identities = 161/331 (48%), Positives = 211/331 (63%), Gaps = 8/331 (2%)

Query: 1   MLALGIEGTAHTLGIGIVSEDK--VLANVFDTLTTEKGGIHPKEAAEHHARLMKPLLRKA 58
           +L LGIE TAHT G+GIVS     V A+V    T  +GGI P+E AE  +      + +A
Sbjct: 9   VLVLGIESTAHTFGVGIVSTRPPIVRADVRRRWTPREGGILPREVAEFFSLHAGEAVAEA 68

Query: 59  LSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKM- 117
           L EAGVS+ D+D +A + GPG+GPALRV AT ARAL+ KY KP+V VNH +AHVE  +  
Sbjct: 69  LGEAGVSIADVDAVAVALGPGMGPALRVGATVARALSAKYGKPLVPVNHAVAHVEAARFT 128

Query: 118 FGVKDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVFARELGLGFP----GGP 173
            G++DPV LYV+GGNT V++   GRYR FGETLDI +GN +D FARE G+  P    G  
Sbjct: 129 TGLRDPVALYVAGGNTTVVSFVAGRYRTFGETLDIALGNLLDTFAREAGIAPPYVAGGLH 188

Query: 174 KVEKLAEKGEKYIELPYAVKGMDLSFSGLLTEAIRKYRSGKYRVEDLAYSFQETAFAALV 233
            V++ AE G     +PY VKG D+SFSG+LT A+R  + G  R+ D+ Y+ +E AF+++V
Sbjct: 189 AVDRCAEGGGFVEGIPYVVKGQDVSFSGILTAALRLLKRGA-RLSDVCYTLREVAFSSVV 247

Query: 234 EVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYT 293
           EVTER +AHT K +  L GGVAAN  L E + +M    G  +      L  DNG MIA T
Sbjct: 248 EVTERCLAHTGKRQATLTGGVAANRVLNEKMSLMAGLHGAVYRPVDVRLSGDNGVMIALT 307

Query: 294 GLRMYKAGISFRLEETIVKQKFRTDEVEIVW 324
           GL  Y  G+     E  ++Q++R DEV+I W
Sbjct: 308 GLAAYLHGVIIDPGEAYIRQRWRIDEVDIPW 338


>dbj|BAA82123.1| (AB023065) O-sialoglycoprotease [Rattus norvegicus]
           Length = 322
           
 Score =  283 bits (716), Expect = 2e-75
 Identities = 148/318 (46%), Positives = 210/318 (65%), Gaps = 8/318 (2%)

Query: 4   LGIEGTAHTLGIGIVSEDKVLANVFDTLTTEKG-GIHPKEAAEHHARLMKPLLRKALSEA 62
           LG EG+A+ +G+G+V +  VLAN   T  T  G G  P + A HH  ++  LL++AL+EA
Sbjct: 5   LGFEGSANKIGVGVVRDGTVLANPRRTYVTAPGTGFLPGDTARHHRAVILDLLQEALTEA 64

Query: 63  GVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKMF-GVK 121
           G++  DID IA+++GPG+G  L  VA  AR +A  + KP++GVNHCI H+E+ ++  G  
Sbjct: 65  GLTPKDIDCIAYTKGPGMGAPLASVAVVARTVAQLWNKPLLGVNHCIGHIEMGRLITGAV 124

Query: 122 DPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGP--KVEKLA 179
           +P  LYVSGGNTQV++    RYR+FGET+DI +GN +D FAR L +     P   +E++A
Sbjct: 125 NPTVLYVSGGNTQVISYSEHRYRIFGETIDIAVGNCLDRFARVLKISNDPSPGYNIEQMA 184

Query: 180 EKGEKYIELPYAVKGMDLSFSGLLT----EAIRKYRSGKYRVEDLAYSFQETAFAALVEV 235
           ++G+K +ELPY VKGMD+SFSG+L+     A R   +G+   EDL +S QET FA LVE+
Sbjct: 185 KRGKKLVELPYTVKGMDVSFSGILSFIEDAAQRMLATGECTPEDLCFSLQETVFAMLVEI 244

Query: 236 TERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGL 295
           TERA+AH    E ++VGGV  N RL+EM+  M ++RG + F      C DNGAMIA  G 
Sbjct: 245 TERAMAHCGSKEALIVGGVGCNVRLQEMMATMCQERGAQLFATDERFCIDNGAMIAQAGW 304

Query: 296 RMYKAGISFRLEETIVKQ 313
            M++AG    L+++ + Q
Sbjct: 305 EMFQAGHRTPLQDSGITQ 322


>gi|6322891 probable calcium-binding protein; Ykr038cp [Saccharomyces
           cerevisiae] >gi|549609|sp|P36132|YK18_YEAST HYPOTHETICAL
           46.6 KDA PROTEIN IN DAL80-GAP1 INTERGENIC REGION
           >gi|539319|pir||S38110 O-sialoglycoprotein endopeptidase
           homolog YKR038c - yeast  (Saccharomyces cerevisiae)
           >gi|486477|emb|CAA82112.1| (Z28263) ORF YKR038c
           [Saccharomyces cerevisiae]
           Length = 421
           
 Score =  263 bits (665), Expect = 2e-69
 Identities = 162/368 (44%), Positives = 215/368 (58%), Gaps = 45/368 (12%)

Query: 2   LALGIEGTAHTLGIGIVS----------------EDKVLANVFDTLTTEKG-GIHPKEAA 44
           +ALG+EG+A+ LG+GIV                 E ++L+N+ DT  T  G G  P++ A
Sbjct: 52  IALGLEGSANKLGVGIVKHPLLPKHANSDLSYDCEAEMLSNIRDTYVTPPGEGFLPRDTA 111

Query: 45  EHHARLMKPLLRKALSEAGVSLD--DIDVIAFSQGPGLGPALRVVATAARALAVKYRKPI 102
            HH      L+++AL+EA +     DIDVI F++GPG+G  L  V  AAR  ++ +  P+
Sbjct: 112 RHHRNWCIRLIKQALAEADIKSPTLDIDVICFTKGPGMGAPLHSVVIAARTCSLLWDVPL 171

Query: 103 VGVNHCIAHVEITK-MFGVKDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVF 161
           VGVNHCI H+E+ + +   ++PV LYVSGGNTQV+A    RYR+FGETLDI IGN +D F
Sbjct: 172 VGVNHCIGHIEMGREITKAQNPVVLYVSGGNTQVIAYSEKRYRIFGETLDIAIGNCLDRF 231

Query: 162 ARELGLGFPGGP--KVEKLAEKG---EKYIELPYAVKGMDLSFSGLLT----------EA 206
           AR L +     P   +E+LA+K    E  +ELPY VKGMDLS SG+L           + 
Sbjct: 232 ARTLKIPNEPSPGYNIEQLAKKAPHKENLVELPYTVKGMDLSMSGILASIDLLAKDLFKG 291

Query: 207 IRKYR--------SGKYRVEDLAYSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANN 258
            +K +          K  VEDL YS QE  FA LVE+TERA+AH   ++V++VGGV  N 
Sbjct: 292 NKKNKILFDKTTGEQKVTVEDLCYSLQENLFAMLVEITERAMAHVNSNQVLIVGGVGCNV 351

Query: 259 RLREMLRIMTEDRGI-KFFVPPYDLCRDNGAMIAYTGLRMYK-AGISFRLEETIVKQKFR 316
           RL+EM+  M +DR   +        C DNG MIA  GL  Y+  GI     ET+V QKFR
Sbjct: 352 RLQEMMAQMCKDRANGQVHATDNRFCIDNGVMIAQAGLLEYRMGGIVKDFSETVVTQKFR 411

Query: 317 TDEVEIVW 324
           TDEV   W
Sbjct: 412 TDEVYAAW 419


>gb|AAG20204.1| (AE005096) O-sialoglycoprotein endopeptidase homolog; Gcp
           [Halobacterium sp. NRC-1]
           Length = 483
           
 Score =  244 bits (616), Expect = 1e-63
 Identities = 133/263 (50%), Positives = 163/263 (61%), Gaps = 3/263 (1%)

Query: 63  GVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITK-MFGVK 121
           G +  DID +AFS+GPGLGP LR+V +AARALA     P+VGVNH +AH+EI +   G +
Sbjct: 14  GAADGDIDAVAFSRGPGLGPCLRIVGSAARALAQALDVPLVGVNHMVAHLEIGRHQSGFQ 73

Query: 122 DPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGPKVEKLAEK 181
            PV L  SG N  VLA   GRYRV GET+D G+GNAID F R +G   PGGPKVE  A  
Sbjct: 74  QPVCLNASGANAHVLAYRNGRYRVLGETMDTGVGNAIDKFTRHVGWQHPGGPKVETHARD 133

Query: 182 GEKYIELPYAVKGMDLSFSGLLTEAIRKYRSGKYRVEDLAYSFQETAFAALVEVTERAVA 241
           GE Y  LPY VKGMD SFSG+++ A      G   V D+    +ET FA L EV ERA+A
Sbjct: 134 GE-YTALPYVVKGMDFSFSGIMSAAKDAVDDG-VPVADVCRGLEETMFAMLTEVAERALA 191

Query: 242 HTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGLRMYKAG 301
            T +DE+VL GGV  N+RLR ML  M   RG  F  P     RDN  MIA  G +M  AG
Sbjct: 192 LTGRDELVLGGGVGQNDRLRGMLEAMCAARGASFHAPEPRFLRDNAGMIAVLGAKMAAAG 251

Query: 302 ISFRLEETIVKQKFRTDEVEIVW 324
            +  + ++ +  +FR DEV + W
Sbjct: 252 ATIPVADSAINSQFRPDEVSVTW 274


>gb|AAK40758.1| O-sialoglycoprotein endopeptidase [Sulfolobus solfataricus]
           Length = 246
           
 Score =  215 bits (541), Expect = 7e-55
 Identities = 115/246 (46%), Positives = 164/246 (65%), Gaps = 7/246 (2%)

Query: 84  LRVVATAARALAVKYRKPIVGVNHCIAHVEITKMFG-VKDPVGLYVSGGNTQVLALEGGR 142
           +RV AT ARA+A+KY K +V VNH I H+EI  +    +DP+ LY+SGGNT +     GR
Sbjct: 1   MRVGATLARAIALKYNKKLVPVNHGIGHIEIGYLTTEARDPLILYLSGGNTIITTFYKGR 60

Query: 143 YRVFGETLDIGIGNAIDVFARELGLGFP----GGPKVEKLAEKGEKYIELPYAVKGMDLS 198
           +RVFGETLDI +GN +DVF RE+ L  P    G   ++  AEKG K ++LPY VKG D+S
Sbjct: 61  FRVFGETLDIALGNMMDVFVREVSLAPPYIINGIHVIDICAEKGNKLLKLPYVVKGQDMS 120

Query: 199 FSGLLTEAIRKYRSGKYRVEDLAYSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANN 258
           FSGLLT A+R    GK ++ED+ YS +E AF  L+E TERA+A T K E+++VGGVAA+ 
Sbjct: 121 FSGLLTAALRVV--GKEKLEDICYSVREIAFDMLLEATERALALTSKKELMIVGGVAASV 178

Query: 259 RLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGLRMYKAGISFRLEETIVKQKFRTD 318
            LR+ L  + ++  ++  + P +   DNGAMIAY G+     G+   ++++ ++ ++R D
Sbjct: 179 SLRKKLEELGKEWNVQIKIVPPEFAGDNGAMIAYAGMLAASKGVFIDVDKSYIRPRWRVD 238

Query: 319 EVEIVW 324
           EV+I W
Sbjct: 239 EVDIPW 244


>sp|P43764|GCP_HAEIN PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROTEASE)
           >gi|1075307|pir||H64074 O-sialoglycoprotein
           endopeptidase (EC 3.4.24.57) - Haemophilus influenzae
           (strain Rd KW20) >gi|1573514|gb|AAC22187.1| (U32735)
           O-sialoglycoprotein endopeptidase (gcp) [Haemophilus
           influenzae Rd]
           Length = 342
           
 Score =  192 bits (482), Expect = 6e-48
 Identities = 125/322 (38%), Positives = 174/322 (53%), Gaps = 22/322 (6%)

Query: 1   MLALGIEGTAHTLGIGIVSEDK-VLANVFDT---LTTEKGGIHPKEAAEHHARLMKPLLR 56
           M  LGIE +    G+ I  E+K ++AN   T   L  + GG+ P+ A+  H R   PL++
Sbjct: 1   MKILGIETSCDETGVAIYDEEKGLIANQLYTQIALHADYGGVVPELASRDHIRKTAPLIK 60

Query: 57  KALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITK 116
            AL EA ++  DID IA++ GPGL  AL V AT AR+LA  +  P +GV+H   H+ +  
Sbjct: 61  AALEEANLTASDIDGIAYTSGPGLVGALLVGATIARSLAYAWNVPAIGVHHMEGHL-LAP 119

Query: 117 MFGVKDP----VGLYVSGGNTQVLALEG-GRYRVFGETLDIGIGNAIDVFARELGLGFPG 171
           M     P    V L VSGG+TQ++ ++G G+Y V GE++D   G A D  A+ LGL +PG
Sbjct: 120 MLDDNSPHFPFVALLVSGGHTQLVRVDGVGKYEVIGESIDDAAGEAFDKTAKLLGLDYPG 179

Query: 172 GPKVEKLAEKG-EKYIELPYAV---KGMDLSFSGLLTEAIRKYRSG--------KYRVED 219
           G  + +LAEKG       P  +    G+D SFSGL T A               +    D
Sbjct: 180 GAALSRLAEKGTPNRFTFPRPMTDRAGLDFSFSGLKTFAANTVNQAIKNEGELIEQTKAD 239

Query: 220 LAYSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPP 279
           +AY+FQ+     L    +RA+  T    +V+ GGV+AN +LRE L  + ++ G + F P 
Sbjct: 240 IAYAFQDAVVDTLAIKCKRALKETGYKRLVIAGGVSANKKLRETLAHLMQNLGGEVFYPQ 299

Query: 280 YDLCRDNGAMIAYTGLRMYKAG 301
              C DNGAMIAYTG    K G
Sbjct: 300 PQFCTDNGAMIAYTGFLRLKQG 321


>sp|P36174|YHSH_HALMA HYPOTHETICAL PROTEIN IN HSH 3'REGION (ORFX) >gi|282647|pir||S27037
           hypothetical protein X - Haloarcula marismortui
           >gi|312781|emb|CAA49709.1| (X70117) HmaORFx [Haloarcula
           marismortui]
           Length = 226
           
 Score =  190 bits (479), Expect = 1e-47
 Identities = 106/222 (47%), Positives = 136/222 (60%), Gaps = 17/222 (7%)

Query: 1   MLALGIEGTAHTLGIGI--------VSEDKVLANVFDTLTTEKGGIHPKEAAEHHARLMK 52
           M  LGIEGTA      +        V++D  +    D    + GGIHP+EAAEH    + 
Sbjct: 1   MRILGIEGTAWAASASVFETPDPARVTDDDHVFIETDAYAPDSGGIHPREAAEHMGEAIP 60

Query: 53  PLLRKALSE----AGVSLDD---IDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGV 105
            ++  A+      AG   DD   ID +AF++GPGLGP LR+VATAARA+A ++  P+VGV
Sbjct: 61  TVVETAIEHTHGRAGRDGDDSAPIDAVAFARGPGLGPCLRIVATAARAVAQRFDVPLVGV 120

Query: 106 NHCIAHVEITK-MFGVKDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDVFARE 164
           NH +AH+E+ +   G   PV L  SG N  +L    GRYRV GET+D G+GNAID F R 
Sbjct: 121 NHMVAHLEVGRHRSGFDSPVCLNASGANAHILGYRNGRYRVLGETMDTGVGNAIDKFTRH 180

Query: 165 LGLGFPGGPKVEKLAEKGEKYIELPYAVKGMDLSFSGLLTEA 206
           +G   PGGPKVE+ A  GE Y ELPY VKGMD SFSG+++ A
Sbjct: 181 IGWSHPGGPKVEQHARDGE-YHELPYVVKGMDFSFSGIMSAA 221


>sp|O66986|GCP_AQUAE PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROTEASE)
           >gi|7444713|pir||G70369 sialoglycoproteinase - Aquifex
           aeolicus >gi|2983364|gb|AAC06951.1| (AE000708)
           sialoglycoprotease [Aquifex aeolicus]
           Length = 335
           
 Score =  190 bits (477), Expect = 2e-47
 Identities = 117/313 (37%), Positives = 182/313 (57%), Gaps = 11/313 (3%)

Query: 1   MLALGIEGTAHTLGIGIVSEDK-VLANVF---DTLTTEKGGIHPKEAAEHHARLMKPLLR 56
           M  L +E +     + I  + K VL NV      + +  GG+ P+ +A  H R + P+  
Sbjct: 1   MRTLAVETSCDETALAIYDDQKGVLGNVILSQAVVHSPFGGVVPELSAREHTRNILPIFD 60

Query: 57  KALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHV-EIT 115
           + L E+ ++L++ID I+F+  PGL  +L V    A+ALA +YRKP+V V+H   H+  + 
Sbjct: 61  RLLKESRINLEEIDFISFTLTPGLILSLVVGVAFAKALAYEYRKPLVPVHHLEGHIYSVF 120

Query: 116 KMFGVKDP-VGLYVSGGNTQV-LALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGP 173
               V+ P + L +SGG+T + L  + GRY   G TLD  +G A D  A+ LGLG+PGGP
Sbjct: 121 LEKKVEYPFLALIISGGHTDLYLVRDFGRYDFLGGTLDDAVGEAYDKVAKMLGLGYPGGP 180

Query: 174 KVEKLAEKGEKYIELPYAVK---GMDLSFSGLLTEAIRKYRSGK-YRVEDLAYSFQETAF 229
            +++LA++G+K   LP  +     ++ SFSGL T  +   +  K  R ED+AYSFQET  
Sbjct: 181 IIDRLAKEGKKLYPLPKPLMEEGNLNFSFSGLKTAILNLLKKEKNVRKEDIAYSFQETVV 240

Query: 230 AALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAM 289
             L+E +  A+  T    +V+VGGV+AN+RLRE+ +  +++ G + ++P   L  DN  M
Sbjct: 241 EILLEKSLWAMKKTGIKRLVVVGGVSANSRLREVFKKASQEYGFELYIPHPSLSTDNALM 300

Query: 290 IAYTGLRMYKAGI 302
           IAY G+  +K G+
Sbjct: 301 IAYAGMERFKRGV 313


>sp|O05518|GCP_BACSU PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROTEASE)
           >gi|7444711|pir||F69786 glycoprotein endopeptidase
           homolog ydiE - Bacillus subtilis
           >gi|1945110|dbj|BAA19718.1| (D88802) P. haemolytica
           o-sialoglycoprotein endopeptidase; P36175 (660)
           transmembrane [Bacillus subtilis]
           >gi|2632907|emb|CAB12413.1| (Z99107) similar to
           glycoprotein endopeptidase [Bacillus subtilis]
           Length = 346
           
 Score =  188 bits (473), Expect = 7e-47
 Identities = 121/318 (38%), Positives = 174/318 (54%), Gaps = 16/318 (5%)

Query: 1   MLALGIEGTAHTLGIGIVSEDK-VLANVFDT-LTTEK--GGIHPKEAAEHHARLMKPLLR 56
           M  LGIE +       IV   K +++NV  + + + K  GG+ P+ A+ HH   +  ++ 
Sbjct: 7   MYVLGIETSCDETAAAIVKNGKEIISNVVASQIESHKRFGGVVPEIASRHHVEQITLVIE 66

Query: 57  KALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITK 116
           +A  +AG++  DID IA ++GPGL  AL +   AA+AL+  Y  P+VGV+H   H+   +
Sbjct: 67  EAFRKAGMTYSDIDAIAVTEGPGLVGALLIGVNAAKALSFAYNIPLVGVHHIAGHIYANR 126

Query: 117 MFG--VKDPVGLYVSGGNTQVLAL-EGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGP 173
           +    V   + L VSGG+T+++ + E G + V GETLD   G A D  AR +GL +PGGP
Sbjct: 127 LVEDIVFPALALVVSGGHTELVYMKEHGSFEVIGETLDDAAGEAYDKVARTMGLPYPGGP 186

Query: 174 KVEKLAEKGEKYIELPYA---VKGMDLSFSGLLTEAIRKYRSGKYR-----VEDLAYSFQ 225
           +++KLAEKG   I LP A       + SFSGL +  I    +   +      EDL+ SFQ
Sbjct: 187 QIDKLAEKGNDNIPLPRAWLEEGSYNFSFSGLKSAVINTLHNASQKGQEIAPEDLSASFQ 246

Query: 226 ETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREML-RIMTEDRGIKFFVPPYDLCR 284
            +    LV  T RA    +  +V+L GGVAAN  LR  L +   +  GI   +PP  LC 
Sbjct: 247 NSVIDVLVTKTARAAKEYDVKQVLLAGGVAANRGLRAALEKEFAQHEGITLVIPPLALCT 306

Query: 285 DNGAMIAYTGLRMYKAGI 302
           DN AMIA  G   ++ GI
Sbjct: 307 DNAAMIAAAGTIAFEKGI 324


>pir||G72411 hypothetical protein TM0145 - Thermotoga maritima (strain MSB8)
           >gi|4980638|gb|AAD35238.1|AE001700_2 (AE001700) secreted
           metalloendopeptidase Gcp, putative [Thermotoga maritima]
           Length = 327
           
 Score =  182 bits (457), Expect = 5e-45
 Identities = 125/316 (39%), Positives = 173/316 (54%), Gaps = 17/316 (5%)

Query: 1   MLALGIEGTAHTLGIGIVSEDKVLANVFDTLTTEK----GGIHPKEAAEHHARLMKPLLR 56
           M  LGIE +     + ++ + K +   F     E     GG+ P+ AA HH + +  LL+
Sbjct: 1   MRVLGIETSCDETAVAVLDDGKNVVVNFTVSQIEVHQKFGGVVPEVAARHHLKNLPILLK 60

Query: 57  KALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITK 116
           KA  +  V  + +DV+A + GPGL  AL V  +AA+ LA+   KP VGVNH  AHV+   
Sbjct: 61  KAFEK--VPPETVDVVAATYGPGLIGALLVGLSAAKGLAISLEKPFVGVNHVEAHVQAVF 118

Query: 117 MFG--VKDP-VGLYVSGGNTQVLAL-EGGRYRVFGETLDIGIGNAIDVFARELGLGFPGG 172
           +    +K P V L VSGG+TQ++ + E     V GETLD   G A D  AR LGLG+PGG
Sbjct: 119 LANPDLKPPLVVLMVSGGHTQLMKVDEDYSMEVLGETLDDSAGEAFDKVARLLGLGYPGG 178

Query: 173 PKVEKLAEKG--EKYIELPYAVKGMD---LSFSGLLTEAIRKYRSGK-YRVEDLAYSFQE 226
           P ++++A+KG  EKY   P  +   D    SF+GL T  +   +  K Y+VED+A SFQ+
Sbjct: 179 PVIDRVAKKGDPEKY-SFPRPMLDDDSYNFSFAGLKTSVLYFLQREKGYKVEDVAASFQK 237

Query: 227 TAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDN 286
                LVE T R   +    ++  VGGVAAN+ LRE +R   E    + F PP +LC DN
Sbjct: 238 AVVDILVEKTFRLARNLGIRKIAFVGGVAANSMLREEVRKRAERWNYEVFFPPLELCTDN 297

Query: 287 GAMIAYTGLRMYKAGI 302
             M+A  G    K G+
Sbjct: 298 ALMVAKAGYEKAKRGM 313


>pir||QQECR6 O-sialoglycoprotein endopeptidase (EC 3.4.24.57) - Escherichia coli
           >gi|882587|gb|AAA89144.1| (U28379) ORF_f337 [Escherichia
           coli] >gi|1789445|gb|AAC76100.1| (AE000388) putative
           O-sialoglycoprotein endopeptidase [Escherichia coli K12]
           Length = 337
           
 Score =  177 bits (445), Expect = 1e-43
 Identities = 120/318 (37%), Positives = 178/318 (55%), Gaps = 19/318 (5%)

Query: 1   MLALGIEGTAHTLGIGIVSEDK-VLANVFDT---LTTEKGGIHPKEAAEHHARLMKPLLR 56
           M  LGIE +    GI I  ++K +LAN   +   L  + GG+ P+ A+  H R   PL++
Sbjct: 1   MRVLGIETSCDETGIAIYDDEKGLLANQLYSQVKLHADYGGVVPELASRDHVRKTVPLIQ 60

Query: 57  KALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITK 116
            AL E+G++  DID +A++ GPGL  AL V AT  R+LA  +  P + V+H   H+ +  
Sbjct: 61  AALKESGLTAKDIDAVAYTAGPGLVGALLVGATVGRSLAFAWDVPAIPVHHMEGHL-LAP 119

Query: 117 MFGVKDP----VGLYVSGGNTQVLALEG-GRYRVFGETLDIGIGNAIDVFARELGLGFPG 171
           M     P    V L VSGG+TQ++++ G G+Y + GE++D   G A D  A+ LGL +PG
Sbjct: 120 MLEDNPPEFPFVALLVSGGHTQLISVTGIGQYELLGESIDDAAGEAFDKTAKLLGLDYPG 179

Query: 172 GPKVEKLAEKGEK---YIELPYAVK-GMDLSFSGLLTEA---IRKYRSGKYRVEDLAYSF 224
           GP + K+A +G         P   + G+D SFSGL T A   IR   +      D+A +F
Sbjct: 180 GPLLSKMAAQGTAGRFVFPRPMTDRPGLDFSFSGLKTFAANTIRDNGTDDQTRADIARAF 239

Query: 225 QETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLR-EMLRIMTEDRGIKFFVPPYDLC 283
           ++     L+   +RA+  T    +V+ GGV+AN  LR ++  +M + RG  F+  P + C
Sbjct: 240 EDAVVDTLMIKCKRALDQTGFKRLVMAGGVSANRTLRAKLAEMMKKRRGEVFYARP-EFC 298

Query: 284 RDNGAMIAYTGLRMYKAG 301
            DNGAMIAY G+  +KAG
Sbjct: 299 TDNGAMIAYAGMVRFKAG 316


>sp|P05852|GCP_ECOLI PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROTEASE)
           >gi|551834|gb|AAA72575.1| (M16194) [Escherichia coli
           rpsU gene encoding ribosomal protein S21, partial cds,
           with 5' flank encoding three unidentified proteins,
           complete cds..], gene products >gi|225555|prf||1306285D
           ORF x,upsU upstream [Escherichia coli]
           Length = 337
           
 Score =  175 bits (440), Expect = 5e-43
 Identities = 119/318 (37%), Positives = 177/318 (55%), Gaps = 19/318 (5%)

Query: 1   MLALGIEGTAHTLGIGIVSEDK-VLANVFDT---LTTEKGGIHPKEAAEHHARLMKPLLR 56
           M  LGIE +    GI I  ++K +LAN   +   L  + GG+ P+ A+  H R   PL++
Sbjct: 1   MRVLGIETSCDETGIAIYDDEKGLLANQLYSQVKLHADYGGVVPELASRDHVRKTVPLIQ 60

Query: 57  KALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITK 116
            AL E+G++  DID +A++ GPGL  AL V AT  R+LA  +  P + V+H   H+ +  
Sbjct: 61  AALKESGLTAKDIDAVAYTAGPGLVGALLVGATVGRSLAFAWDVPAIPVHHMEGHL-LAP 119

Query: 117 MFGVKDP----VGLYVSGGNTQVLALEG-GRYRVFGETLDIGIGNAIDVFARELGLGFPG 171
           M     P    V L V GG+TQ++++ G G+Y + GE++D   G A D  A+ LGL +PG
Sbjct: 120 MLEDNPPEFPFVALLVCGGHTQLISVTGIGQYELLGESIDDAAGEAFDKTAKLLGLDYPG 179

Query: 172 GPKVEKLAEKGEK---YIELPYAVK-GMDLSFSGLLTEA---IRKYRSGKYRVEDLAYSF 224
           GP + K+A +G         P   + G+D SFSGL T A   IR   +      D+A +F
Sbjct: 180 GPLLSKMAAQGTAGRFVFPRPMTDRPGLDFSFSGLKTFAANTIRDNGTDDQTRADIARAF 239

Query: 225 QETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLR-EMLRIMTEDRGIKFFVPPYDLC 283
           ++     L+   +RA+  T    +V+ GGV+AN  LR ++  +M + RG  F+  P + C
Sbjct: 240 EDAVVDTLMIKCKRALDQTGFKRLVMAGGVSANRTLRAKLAEMMKKRRGEVFYARP-EFC 298

Query: 284 RDNGAMIAYTGLRMYKAG 301
            DNGAMIAY G+  +KAG
Sbjct: 299 TDNGAMIAYAGMVRFKAG 316


>sp|O86793|GCP_STRCO PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROTEASE)
           >gi|7481089|pir||T35581 probable O-sialoglycoprotein
           endopeptidase - Streptomyces coelicolor
           >gi|3449264|emb|CAA20408.1| (AL031317) putative
           O-sialoglycoprotein endopeptidase [Streptomyces
           coelicolor A3(2)]
           Length = 374
           
 Score =  175 bits (440), Expect = 5e-43
 Identities = 120/315 (38%), Positives = 166/315 (52%), Gaps = 19/315 (6%)

Query: 2   LALGIEGTAHTLGIGIVSEDKVLANVFDTLTTEK---GGIHPKEAAEHHARLMKPLLRKA 58
           L LGIE +    G+G+V    +LA+   +   E    GG+ P+ A+  H   M P + +A
Sbjct: 9   LVLGIETSCDETGVGVVRGTTLLADAVASSVDEHARFGGVVPEVASRAHLEAMVPTIDRA 68

Query: 59  LSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKM- 117
           L EAGVS  D+D IA + GPGL  AL V  +AA+A A    KP+ GVNH  +H+ + ++ 
Sbjct: 69  LKEAGVSARDLDGIAVTAGPGLAGALLVGVSAAKAYAYALGKPLYGVNHLASHICVDQLE 128

Query: 118 -FGVKDP-VGLYVSGGNTQVLALEG--GRYRVFGETLDIGIGNAIDVFARELGLGFPGGP 173
              + +P + L VSGG++ +L         R  G T+D   G A D  AR L LGFPGGP
Sbjct: 129 HGALPEPTMALLVSGGHSSLLLSTDITSDVRPLGATIDDAAGEAFDKIARVLNLGFPGGP 188

Query: 174 KVEKLAEKGE-KYIELPYAVKG-----MDLSFSGLLTEAIR----KYRSG-KYRVEDLAY 222
            +++ A +G+   I  P  + G      D SFSGL T   R    K  +G +  V D++ 
Sbjct: 189 VIDRYAREGDPNAIAFPRGLTGPRDAAYDFSFSGLKTAVARWIEAKRAAGEEVPVRDVSA 248

Query: 223 SFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDL 282
           SFQE     L     RA      D +++ GGVAAN+RLR + +   E  GI+  VP   L
Sbjct: 249 SFQEAVVDVLTRKAVRACKDEGVDHLMIGGGVAANSRLRALAQERCEAAGIRLRVPRPKL 308

Query: 283 CRDNGAMIAYTGLRM 297
           C DNGAM+A  G  M
Sbjct: 309 CTDNGAMVAALGAEM 323


>pir||H83572 O-sialoglycoprotein endopeptidase PA0580 [imported] - Pseudomonas
           aeruginosa (strain PAO1)
           >gi|9946451|gb|AAG03969.1|AE004494_5 (AE004494)
           O-sialoglycoprotein endopeptidase [Pseudomonas
           aeruginosa]
           Length = 341
           
 Score =  173 bits (435), Expect = 2e-42
 Identities = 118/322 (36%), Positives = 180/322 (55%), Gaps = 23/322 (7%)

Query: 1   MLALGIEGTAHTLGIGIV-SEDKVLAN-VFDTLTTEK--GGIHPKEAAEHHARLMKPLLR 56
           M  LG+E +    G+ +  SE  +LA+ +F  +   +  GG+ P+ A+  H + M PL+R
Sbjct: 1   MRVLGLETSCDETGVALYDSERGLLADALFSQIDLHRVYGGVVPELASRDHVKRMLPLIR 60

Query: 57  KALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITK 116
           + L E+G +  DID IA++ GPGL  AL V A+ A+A+A  +  P VGV+H   H+ +  
Sbjct: 61  QVLDESGCTPADIDAIAYTAGPGLVGALLVGASCAQAMAFAWGVPAVGVHHMEGHL-LAP 119

Query: 117 MFGVKDP----VGLYVSGGNTQVLALEG-GRYRVFGETLDIGIGNAIDVFARELGLGFPG 171
           M   + P    V L VSGG+TQ++ ++G GRY++ GE++D   G A D  A+ +GLG+PG
Sbjct: 120 MLEEQPPRFPFVALLVSGGHTQLVRVDGIGRYQLLGESVDDAAGEAFDKTAKLIGLGYPG 179

Query: 172 GPKVEKLAEKGEK---YIELPYAVK-GMDLSFSGLLTEAIRKYR-------SGKYRVEDL 220
           GP++ +LAE+G         P   + G+D SFSGL T  +  ++         +    D+
Sbjct: 180 GPEIARLAERGTPGRFVFPRPMTDRPGLDFSFSGLKTFTLNTWQRCVEAGDDSEQTRCDI 239

Query: 221 AYSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREML-RIMTEDRGIKFFVPP 279
           A +FQ      L+    RA+  T    +V+ GGV+AN  LR  L +++ E +G  F+  P
Sbjct: 240 ALAFQTAVVETLLIKCRRALKQTGLKNLVIAGGVSANQALRSGLEKMLGEMKGQVFYARP 299

Query: 280 YDLCRDNGAMIAYTGLRMYKAG 301
              C DNGAMIAY G +   AG
Sbjct: 300 -RFCTDNGAMIAYAGCQRLLAG 320


>dbj|BAB04267.1| (AP001508) glycoprotein endopeptidase [Bacillus halodurans]
           Length = 343
           
 Score =  173 bits (435), Expect = 2e-42
 Identities = 107/304 (35%), Positives = 163/304 (53%), Gaps = 15/304 (4%)

Query: 2   LALGIEGTAHTLGIGIVSEDK-VLANVFDT-LTTEK--GGIHPKEAAEHHARLMKPLLRK 57
           L L IE +       ++     +L+NV  + + + K  GG+ P+ A+ HH   +  ++ +
Sbjct: 11  LILAIETSCDETSAAVIENGTTILSNVVSSQIDSHKRFGGVVPEIASRHHVEQITVIVEE 70

Query: 58  ALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKM 117
           A+ EAGV   D+  +A ++GPGL  AL +   AA+A+A  ++ P++GV+H   H+   ++
Sbjct: 71  AMHEAGVDFADLAAVAVTEGPGLVGALLIGVNAAKAIAFAHQLPLIGVHHIAGHIYANRL 130

Query: 118 FGVKD--PVGLYVSGGNTQVLALEG-GRYRVFGETLDIGIGNAIDVFARELGLGFPGGPK 174
               +   + L VSGG+T+++ +E  G + V GET D  +G A D  AR LGL +PGGP 
Sbjct: 131 LKELEFPLLALVVSGGHTELIYMENHGEFEVIGETRDDAVGEAYDKVARTLGLPYPGGPH 190

Query: 175 VEKLAEKGEKYIELPYA---VKGMDLSFSGLLTEAIRKYRSGKYR-----VEDLAYSFQE 226
           +++LA  GE  ++ P A       D SFSGL +  I    + K R      ED+A SFQ 
Sbjct: 191 IDRLAVNGEDTLQFPRAWLEPDSFDFSFSGLKSAVINTLHNAKQRGENVQAEDVAASFQA 250

Query: 227 TAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDN 286
           +    LV  T++A    +  +V+L GGVAAN  LR  L        I   +PP  LC DN
Sbjct: 251 SVIDVLVTKTKKAAEEYKVRQVLLAGGVAANKGLRTALEEAFFKEPIDLVIPPLSLCTDN 310

Query: 287 GAMI 290
            AMI
Sbjct: 311 AAMI 314


>pir||D82807 O-sialoglycoprotein endopeptidase XF0435 [imported] - Xylella
           fastidiosa (strain 9a5c)
           >gi|9105277|gb|AAF83245.1|AE003894_10 (AE003894)
           O-sialoglycoprotein endopeptidase [Xylella fastidiosa]
           Length = 348
           
 Score =  172 bits (432), Expect = 4e-42
 Identities = 121/328 (36%), Positives = 176/328 (52%), Gaps = 35/328 (10%)

Query: 1   MLALGIEGTAHTLGIGIVSEDKVLA--------NVFD--TLTTEKGGIHPKEAAEHHARL 50
           M  +GIE +    G+ +   D  L+        +V+    L  E GG+ P+ A+  H R 
Sbjct: 1   MKIIGIESSCDETGVAVY--DTALSGFAALRAHSVYSQVALHAEYGGVVPELASRDHVRK 58

Query: 51  MKPLLRKALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIA 110
           + PLLR+ L+EA +S++++D +A++ GPGL  AL V A  ARALA     P +GV+H   
Sbjct: 59  LLPLLRQTLAEAKLSVEELDGVAYTAGPGLVGALLVGAGVARALAWALEVPAIGVHHMEG 118

Query: 111 HVEITKMFGVKDP----VGLYVSGGNTQVLALEG-GRYRVFGETLDIGIGNAIDVFAREL 165
           H+ ++ +     P    V L VSGG+TQ++A++  G YR+ GETLD   G A D  A+ +
Sbjct: 119 HL-LSPLLEDDPPEVPFVALLVSGGHTQLVAVDAIGDYRLLGETLDDAAGEAFDKVAKLM 177

Query: 166 GLGFPGGPKVEKLAEKG--------EKYIELPYAVKGMDLSFSGLLTEAIRKYR----SG 213
           GL +PGGP++  LAE+G           ++ P    G+D SFSGL T+ +  +R    S 
Sbjct: 178 GLPYPGGPQLAALAEQGIPGRFCFTRPMVDRP----GLDFSFSGLKTQVLLAWRNSDQSD 233

Query: 214 KYRVEDLAYSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGI 273
             RV D+A  F++     L    ERA+       +V+ GGV AN  LR  L+ M   RG 
Sbjct: 234 AIRV-DVARGFEDAVVDTLAIKCERALDTVACQTLVVAGGVGANKCLRARLQAMCRQRGG 292

Query: 274 KFFVPPYDLCRDNGAMIAYTGLRMYKAG 301
           +   P   LC DNGAMIA+ G    +AG
Sbjct: 293 RACFPRPALCTDNGAMIAFAGALRLQAG 320


>pir||C81986 probable O-sialoglycoprotein endopeptidase (EC 3.4.24.57) NMA0661
           [imported] - Neisseria meningitidis (group A strain
           Z2491) >gi|7379390|emb|CAB83948.1| (AL162753) putative
           O-sialoglycoprotein endopeptidase [Neisseria
           meningitidis Z2491]
           Length = 354
           
 Score =  169 bits (424), Expect = 4e-41
 Identities = 118/329 (35%), Positives = 171/329 (51%), Gaps = 36/329 (10%)

Query: 1   MLALGIEGTAHTLGIGIVSEDKVL-ANVFDT---LTTEKGGIHPKEAAEHHARLMKPLLR 56
           ML LGIE +    G+ +   ++ L A+   T   +  E GG+ P+ A+  H R + PL  
Sbjct: 1   MLVLGIESSCDETGVALYDTERGLRAHCLHTQMAMHAEYGGVVPELASRDHIRRLVPLTE 60

Query: 57  KALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITK 116
             L++AG S  DID +AF+QGPGLG AL   ++ A ALA+   KP++ V+H   H+ ++ 
Sbjct: 61  GCLAQAGASYGDIDAVAFTQGPGLGGALLAGSSYANALALALDKPVIPVHHLEGHL-LSP 119

Query: 117 MFGVKDP----VGLYVSGGNTQVLALEG-GRYRVFGETLDIGIGNAIDVFARELGLGFPG 171
           +   + P    V L VSGG+TQ++A+ G G Y + GE++D   G A D  A+ LGL +PG
Sbjct: 120 LLAEEKPDFPFVALLVSGGHTQIMAVRGIGDYALLGESVDDAAGEAFDKTAKLLGLPYPG 179

Query: 172 GPKVEKLAEKG--EKYIELPYAVKGMDL--SFSGLLT---EAIRKYRS-------GKYRV 217
           G K+ +LAE G  E ++     +   DL  SFSGL T    A+ K R+        +   
Sbjct: 180 GAKLSELAESGRPEAFVFPRPMIHSDDLQMSFSGLKTAVLTAVEKVRAENGADDIPEQTR 239

Query: 218 EDLAYSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMT--------- 268
            D+  +FQ+     L    ++A+  T    VV+ GGV AN +LRE    MT         
Sbjct: 240 NDICRAFQDAVVDVLAAKVKKALLQTGFRTVVVAGGVGANRKLRETFGNMTVQIPTPKGK 299

Query: 269 ---EDRGIKFFVPPYDLCRDNGAMIAYTG 294
                  +  F PP   C DNGAMIA+ G
Sbjct: 300 PKHPSEKVSVFFPPTAYCTDNGAMIAFAG 328


>sp|P36175|GCP_PASHA O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROTEASE)
           >gi|97190|pir||A38108 O-sialoglycoprotein endopeptidase
           (EC 3.4.24.57) [validated] - Pasteurella haemolytica
           (serotype A1) >gi|561690|gb|AAA80282.1| (U15958)
           sialoglycoprotease [Pasteurella haemolytica]
           Length = 325
           
 Score =  169 bits (423), Expect = 5e-41
 Identities = 115/320 (35%), Positives = 170/320 (52%), Gaps = 22/320 (6%)

Query: 1   MLALGIEGTAHTLGIGIVSEDK-VLANVFDT---LTTEKGGIHPKEAAEHHARLMKPLLR 56
           M  LGIE +    G+ I  EDK ++AN   +   +  + GG+ P+ A+  H R   PL++
Sbjct: 1   MRILGIETSCDETGVAIYDEDKGLVANQLYSQIDMHADYGGVVPELASRDHIRKTLPLIQ 60

Query: 57  KALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITK 116
           +AL EA +   DID IA++ GPGL  AL V +T AR+LA  +  P +GV+H   H+ +  
Sbjct: 61  EALKEANLQPSDIDGIAYTAGPGLVGALLVGSTIARSLAYAWNVPALGVHHMEGHL-LAP 119

Query: 117 MFGVKDP----VGLYVSGGNTQVLALEG-GRYRVFGETLDIGIGNAIDVFARELGLGFPG 171
           M     P    V L +SGG+TQ++ ++G G+Y + GE++D   G A D   + LGL +P 
Sbjct: 120 MLEENAPEFPFVALLISGGHTQLVKVDGVGQYELLGESIDDAAGEAFDKTGKLLGLDYPA 179

Query: 172 GPKVEKLAEKGE----KYIELPYAVKGMDLSFSGLLTEAIRKYRSG--------KYRVED 219
           G  + KLAE G     K+        G+D SFSGL T A    ++         +    D
Sbjct: 180 GVAMSKLAESGTPNRFKFPRPMTDRPGLDFSFSGLKTFAANTIKANLNENGELDEQTKCD 239

Query: 220 LAYSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPP 279
           +A++FQ+     ++   +RA+  T    +V+ GGV+AN +LR  L  M +    + F P 
Sbjct: 240 IAHAFQQAVVDTILIKCKRALEQTGYKRLVMAGGVSANKQLRADLAEMMKKLKGEVFYPR 299

Query: 280 YDLCRDNGAMIAYTGLRMYK 299
              C DNGAMIAYTG    K
Sbjct: 300 PQFCTDNGAMIAYTGFLRLK 319


>pir||C81040 O-sialoglycoprotein endopeptidase NMB1802 [imported] - Neisseria
           meningitidis (group B strain MD58)
           >gi|7227056|gb|AAF42139.1| (AE002530)
           O-sialoglycoprotein endopeptidase [Neisseria
           meningitidis MC58]
           Length = 354
           
 Score =  168 bits (422), Expect = 6e-41
 Identities = 118/329 (35%), Positives = 171/329 (51%), Gaps = 36/329 (10%)

Query: 1   MLALGIEGTAHTLGIGIVSEDKVL-ANVFDT---LTTEKGGIHPKEAAEHHARLMKPLLR 56
           ML LGIE +    G+ +   ++ L A+   T   +  E GG+ P+ A+  H R + PL  
Sbjct: 1   MLVLGIESSCDETGVALYDTERGLRAHCLHTQMAMHAEYGGVVPELASRDHIRRLVPLTE 60

Query: 57  KALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITK 116
             L++AG S  DID +AF+QGPGLG AL   ++ A ALA+   KP++ V+H   H+ ++ 
Sbjct: 61  GCLAQAGASYGDIDAVAFTQGPGLGGALLAGSSYANALALALDKPVIPVHHLEGHL-LSP 119

Query: 117 MFGVKDP----VGLYVSGGNTQVLALEG-GRYRVFGETLDIGIGNAIDVFARELGLGFPG 171
           +   + P    V L VSGG+TQ++A+ G G Y + GE++D   G A D  A+ LGL +PG
Sbjct: 120 LLAEEKPDFPFVALLVSGGHTQIMAVRGIGDYALLGESVDDAAGEAFDKTAKLLGLLYPG 179

Query: 172 GPKVEKLAEKG--EKYIELPYAVKGMDL--SFSGLLT---EAIRKYRS-------GKYRV 217
           G K+ +LAE G  E ++     +   DL  SFSGL T    A+ K R+        +   
Sbjct: 180 GAKLSELAESGRFEAFVFPRPMIHSDDLQMSFSGLKTAVLTAVEKVRAENGADDIPEQTR 239

Query: 218 EDLAYSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMT--------- 268
            D+  +FQ+     L    ++A+  T    VV+ GGV AN +LRE    MT         
Sbjct: 240 NDICRAFQDAVVDVLAAKVKKALLQTGFRTVVVAGGVGANRKLRETFGNMTVQIPTPKGK 299

Query: 269 ---EDRGIKFFVPPYDLCRDNGAMIAYTG 294
                  +  F PP   C DNGAMIA+ G
Sbjct: 300 PKHPSEKVSVFFPPTAYCTDNGAMIAFAG 328


>gb|AAF32396.1|AF224466_3 (AF224466) sialylglycoprotease [Haemophilus ducreyi]
           Length = 348
           
 Score =  166 bits (415), Expect = 4e-40
 Identities = 113/322 (35%), Positives = 169/322 (52%), Gaps = 22/322 (6%)

Query: 1   MLALGIEGTAHTLGIGIVSEDK-VLANVFDT---LTTEKGGIHPKEAAEHHARLMKPLLR 56
           M  LGIE +    G+ I  E + ++AN   +   +  + GG+ P+ A+  H R   PL++
Sbjct: 1   MRILGIETSCDETGVAIYDEQRGLIANQLYSQIEMHADYGGVVPELASRDHIRKTLPLIQ 60

Query: 57  KALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITK 116
            AL EA ++  +ID IA++ GPGL  AL V AT ARALA  +  P + V+H   H+ +  
Sbjct: 61  AALKEANLTASEIDGIAYTAGPGLVGALLVGATIARALAYAWNVPALAVHHMEGHL-MAP 119

Query: 117 MFGVKDP----VGLYVSGGNTQVLALEG-GRYRVFGETLDIGIGNAIDVFARELGLGFPG 171
           M     P    + L +SGG+TQ++ + G G Y + GE++D   G A D   + LGL +P 
Sbjct: 120 MLEENPPEFPFIALLISGGHTQLIKVAGVGEYEILGESIDDAAGEAFDKTGKLLGLDYPA 179

Query: 172 GPKVEKLAEKG-EKYIELPYAV---KGMDLSFSGLLTEAIRKY-----RSGKYRVE---D 219
           G  + +LAEKG       P  +    G+D SFSGL T A          +G+   +   D
Sbjct: 180 GVALSQLAEKGTPNRFVFPRPMTDRPGLDFSFSGLKTFAANTINAQLDENGQLNEQTRCD 239

Query: 220 LAYSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPP 279
           +A++FQ+     ++   +RA+  T    +V+ GGV+AN +LR  L  M +    + + P 
Sbjct: 240 IAHAFQQAVVDTIIIKCKRALQQTGYSRLVMAGGVSANKQLRAELATMMQALKGQVYYPR 299

Query: 280 YDLCRDNGAMIAYTGLRMYKAG 301
              C DNGAMIAYTG    K G
Sbjct: 300 PQFCTDNGAMIAYTGFIRLKKG 321


>sp|P74034|GCP_SYNY3 PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROTEASE)
           >gi|7444708|pir||S75548 sialoglycoproteinase -
           Synechocystis sp. (strain PCC 6803)
           >gi|1653193|dbj|BAA18109.1| (D90911) sialoglycoprotease
           [Synechocystis sp.]
           Length = 348
           
 Score =  164 bits (411), Expect = 1e-39
 Identities = 113/321 (35%), Positives = 170/321 (52%), Gaps = 21/321 (6%)

Query: 2   LALGIEGTAHTLGIGIVSEDKVLANVFDT-LTTEK--GGIHPKEAAEHHARLMKPLLRKA 58
           + L IE +     + IV+   V +NV  + + T +  GG+ P+ A+  H  L+   L +A
Sbjct: 3   IILAIETSCDETAVAIVNNRNVCSNVVSSQIQTHQIFGGVVPEVASRQHLLLINTCLDQA 62

Query: 59  LSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKMF 118
           L  +G+   +I+ IA +  PGL  AL V  TAA+ LA+ ++KP +GV+H   H+  + + 
Sbjct: 63  LQASGLGWPEIEAIAVTVAPGLAGALMVGVTAAKTLAMVHQKPFLGVHHLEGHIYASYLS 122

Query: 119 --GVKDP-VGLYVSGGNTQVLALEG-GRYRVFGETLDIGIGNAIDVFARELGLGFPGGPK 174
              ++ P + L VSGG+T ++ ++G G YR  G T D   G A D  AR L LG+PGGP 
Sbjct: 123 QPDLQPPFLCLLVSGGHTSLIHVKGCGDYRQLGTTRDDAAGEAFDKVARLLDLGYPGGPA 182

Query: 175 VEKLAEKG--------EKYIELPY-AVKGMDLSFSGLLTEAIR-----KYRSGKYRVEDL 220
           +++ A++G        E  I LP       D SFSGL T  +R     K  S    V+DL
Sbjct: 183 IDRAAKQGDPGTFKLPEGKISLPQGGYHPYDSSFSGLKTAMLRLTQELKQSSAPLPVDDL 242

Query: 221 AYSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPY 280
           A SFQ+T   +L + T + V       + + GGVAAN+RLR  L+   ++  ++ F PP 
Sbjct: 243 AASFQDTVARSLTKKTIQCVLDHGLTTITVGGGVAANSRLRYHLQTAAQEHQLQVFFPPL 302

Query: 281 DLCRDNGAMIAYTGLRMYKAG 301
             C DN AMIA      ++ G
Sbjct: 303 KFCTDNAAMIACAAADHFQNG 323


>gb|AAB82636.1| (AC002387) putative O-sialoglycoprotein endopeptidase [Arabidopsis
           thaliana]
           Length = 463
           
 Score =  155 bits (388), Expect = 6e-37
 Identities = 110/318 (34%), Positives = 171/318 (53%), Gaps = 17/318 (5%)

Query: 1   MLALGIEGTAHTLGIGIVSEDKVLANVFDT-LTTEKGGIHPKEAAEHHARLMKPLLRKAL 59
           ++ LGIE +       +VS    L++     L  + GG+ PK+A E H+R++  +++ AL
Sbjct: 84  LVVLGIETSCDDTAAAVVSPFNHLSSSCRAELLVQYGGVAPKQAEEAHSRVIDKVVQDAL 143

Query: 60  SEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKMFG 119
            +A ++  D+  +A + GPGL   LRV    AR +A  +  PIVGV+H  AH  + ++  
Sbjct: 144 DKANLTEKDLSAVAVTIGPGLSLCLRVGVRKARRVAGNFSLPIVGVHHMEAHALVARLVE 203

Query: 120 VK---DPVGLYVSGG-NTQVLALEGGRYRVFGETLDIGIGNAIDVFARELGLGF--PGGP 173
            +     + L +SGG N  VLA + G+Y   G T+D  IG A D  A+ LGL     GGP
Sbjct: 204 QELSFPFMALLISGGHNLLVLAHKLGQYTQLGTTVDDAIGEAFDKTAKWLGLDMHRSGGP 263

Query: 174 KVEKLAEKGE-KYIELPYAV---KGMDLSFSGLLTEAIRKYRSGKYRVE-DLAYSFQETA 228
            VE+LA +G+ K ++    +   K  + S++GL T+      + + R   D+A SFQ  A
Sbjct: 264 AVEELALEGDAKSVKFNVPMKYHKDCNFSYAGLKTQVRLAIEAKEIRNRADIAASFQRVA 323

Query: 229 FAALVEVTERAVAHTEKDE-----VVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLC 283
              L E  ERA+    + E     +V+ GGVA+N  +R  L  + E++ +K   PP  LC
Sbjct: 324 VLHLEEKCERAIDWALELEPSIKHMVISGGVASNKYVRLRLNNIVENKNLKLVCPPPSLC 383

Query: 284 RDNGAMIAYTGLRMYKAG 301
            DNG M+A+TGL  ++ G
Sbjct: 384 TDNGVMVAWTGLEHFRVG 401


>sp|O51710|GCP_BORBU PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROTEASE)
           >gi|7444712|pir||H70195 sialoglycoproteinase (gcp)
           homolog - Lyme disease spirochete
           >gi|2688702|gb|AAC67111.1| (AE001176) sialoglycoprotease
           (gcp) [Borrelia burgdorferi]
           Length = 346
           
 Score =  152 bits (381), Expect = 4e-36
 Identities = 104/315 (33%), Positives = 163/315 (51%), Gaps = 21/315 (6%)

Query: 1   MLALGIEGTAHTLGIGIVSED-KVLANVFDTLTTEKG--GIHPKEAAEHHARLMKPLLRK 57
           M  LGIE +     + +V     +L+N+    T  K   GI P+ A+  H   +  +  K
Sbjct: 1   MKVLGIETSCDDCCVAVVENGIHILSNIKLNQTEHKKYYGIVPEIASRLHTEAIMSVCIK 60

Query: 58  ALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKM 117
           AL +A   + +ID+IA +  PGL  +L V    A+ LA+  +KPI+ ++H + H+    M
Sbjct: 61  ALKKANTKISEIDLIAVTSRPGLIGSLIVGLNFAKGLAISLKKPIICIDHILGHLYAPLM 120

Query: 118 FG-VKDP-VGLYVSGGNTQVLALEG-GRYRVFGETLDIGIGNAIDVFARELGLGFPGGPK 174
              ++ P + L +SGG+T +   +      + G TLD   G A D  A+   +GFPGGP 
Sbjct: 121 HSKIEYPFISLLLSGGHTLIAKQKNFDDVEILGRTLDDACGEAFDKVAKHYDMGFPGGPN 180

Query: 175 VEKLAEKG-EKYIELPYAV-----KGMDLSFSGLLTEAIRKYRSGKYR-----VEDLAYS 223
           +E++++ G E   + P           D S+SGL T  I +    K +       ++A S
Sbjct: 181 IEQISKNGDENTFQFPVTTFKKKENWYDFSYSGLKTACIHQLEKFKSKDNPTTKNNIAAS 240

Query: 224 FQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLC 283
           FQ+ AF  L+   +RA+  T+ +++V+ GGVA+N  LRE +    +   I+ + PP DLC
Sbjct: 241 FQKAAFENLITPLKRAIKDTQINKLVIAGGVASNLYLREKI----DKLKIQTYYPPLDLC 296

Query: 284 RDNGAMIAYTGLRMY 298
            DNGAMIA  G  MY
Sbjct: 297 TDNGAMIAGLGFNMY 311


>pir||A71545 probable o-sialoglycoprotein endopeptidase - Chlamydia trachomatis
           (serotype D, strain UW3/Cx) >gi|3328603|gb|AAC67789.1|
           (AE001293) O-Sialoglycoprotein Endopeptidase [Chlamydia
           trachomatis]
           Length = 338
           
 Score =  149 bits (372), Expect = 5e-35
 Identities = 100/318 (31%), Positives = 158/318 (49%), Gaps = 23/318 (7%)

Query: 1   MLALGIEGTAHTLGIGIVSEDKVLANVFDT--LTTEKGGIHPKEAAEHHARLMKPLLRKA 58
           ML LG+E +       +V   K+LAN   +  +    GG+ P+ A+  H +    LL  A
Sbjct: 1   MLTLGLESSCDETSCSLVQNGKILANKIASQDIHASYGGVIPELASRAHLQTFPELLTAA 60

Query: 59  LSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKMF 118
              AGVSL+DI++I+ +  PGL  AL +    A+ LA   ++P++GVNH  AH+    M 
Sbjct: 61  TQSAGVSLEDIELISVANTPGLIGALSIGVNFAKGLASGLKRPLIGVNHVEAHLYAACME 120

Query: 119 GVK---DPVGLYVSGGNTQVLAL-EGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGPK 174
                   +GL +SG +T +  + +   + + G+T D  IG   D  AR LGL +PGG K
Sbjct: 121 APATQFPALGLAISGAHTSLFLMPDATTFLLIGKTRDDAIGETFDKVARFLGLPYPGGQK 180

Query: 175 VEKLAEKG--EKYIELPYAVKGMDLSFSGLLTEAIRKYRS------------GKYRVEDL 220
           +E+LA +G  + +   P  V G D SFSGL T  +   +              + +  ++
Sbjct: 181 LEELAREGDADAFAFSPARVSGYDFSFSGLKTAVLYALKGNNSSAKAPFPEVSETQKRNI 240

Query: 221 AYSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPY 280
           A SFQ+  F  + +     V     + +++ GGVA N+  R   R++ +   +  + P  
Sbjct: 241 AASFQKAVFMTIAQKLPDIVKTFSCESLIVGGGVANNSYFR---RLLNQICSLPIYFPSS 297

Query: 281 DLCRDNGAMIAYTGLRMY 298
            LC DN AMIA  G R++
Sbjct: 298 QLCSDNAAMIAGLGERLF 315


>pir||H72106 o-sialoglycoprotein endopeptidase - Chlamydophila pneumoniae
           (strain CWL029) >gi|4376465|gb|AAD18347.1| (AE001606)
           O-Sialoglycoprotein Endopeptidase [Chlamydophila
           pneumoniae CWL029] >gi|8163461|gb|AAF73688.1| (AE002216)
           O-sialoglycoprotein endopeptidase [Chlamydophila
           pneumoniae AR39] >gi|8978567|dbj|BAA98404.1| (AP002545)
           O-sialoglycoprotein endopeptidase [Chlamydophila
           pneumoniae J138]
           Length = 344
           
 Score =  148 bits (371), Expect = 6e-35
 Identities = 102/315 (32%), Positives = 156/315 (49%), Gaps = 24/315 (7%)

Query: 1   MLALGIEGTAHTLGIGIVSEDK-VLANVFDT--LTTEKGGIHPKEAAEHHARLMKPLLRK 57
           ML LG+E +       IV+EDK +LAN+  +  +    GG+ P+ A+  H  +   ++ K
Sbjct: 1   MLTLGLESSCDETACAIVNEDKQILANIIASQDIHASYGGVVPELASRAHLHIFPQVINK 60

Query: 58  ALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKM 117
           AL +A + ++D+D+IA +Q PGL  +L V     + +A+  +K ++GVNH  AH+    M
Sbjct: 61  ALQQANLLIEDMDLIAVTQTPGLIGSLSVGVHFGKGIAIGAKKSLIGVNHVEAHLYAAYM 120

Query: 118 F--GVKDP-VGLYVSGGNTQVLALEG-GRYRVFGETLDIGIGNAIDVFARELGLGFPGGP 173
               V+ P +GL VSG +T    +E    Y++ G+T D  IG   D   R LGL +P GP
Sbjct: 121 AAQNVQFPALGLVVSGAHTAAFFIENPTSYKLIGKTRDDAIGETFDKVGRFLGLPYPAGP 180

Query: 174 KVEKLAEKG--EKYIELPYAVKGMDLSFSGLLTEAIRKYRSGK------------YRVED 219
            +EKLA +G  + Y   P  V   D SFSGL T  +   +                +  D
Sbjct: 181 LIEKLALEGSEDSYPFSPAKVPNYDFSFSGLKTAVLYAIKGNNSSPRSPAPEISLEKQRD 240

Query: 220 LAYSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPP 279
           +A SFQ+ A   + +     +       +++ GGVA N   R  ++       +  + PP
Sbjct: 241 IAASFQKAACTTIAQKLPTIIKEFSCRSILIGGGVAINEYFRSAIQTAC---NLPVYFPP 297

Query: 280 YDLCRDNGAMIAYTG 294
             LC DN AMIA  G
Sbjct: 298 AKLCSDNAAMIAGLG 312


>sp|Q50709|GCP_MYCTU PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROTEASE)
           >gi|7444707|pir||H70737 probable o-sialoglycoprotein
           endopeptidase - Mycobacterium tuberculosis (strain
           H37RV) >gi|1449368|emb|CAB01004.1| (Z77165) gcp
           [Mycobacterium tuberculosis]
           Length = 344
           
 Score =  143 bits (357), Expect = 3e-33
 Identities = 110/320 (34%), Positives = 155/320 (48%), Gaps = 24/320 (7%)

Query: 4   LGIEGTAHTLGIGIVSEDK-----VLANVFDTLTTEK---GGIHPKEAAEHHARLMKPLL 55
           LGIE +    G+GI   D      +LA+   +   E    GG+ P+ A+  H   + P +
Sbjct: 5   LGIETSCDETGVGIARLDPDGTVTLLADEVASSVDEHVRFGGVVPEIASRAHLEALGPAM 64

Query: 56  RKALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHV--E 113
           R+AL+ AG  L   D++A + GPGL  AL V   AA+A +  +  P   VNH   H+  +
Sbjct: 65  RRALAAAG--LKQPDIVAATIGPGLAGALLVGVAAAKAYSAAWGVPFYAVNHLGGHLAAD 122

Query: 114 ITKMFGVKDPVGLYVSGGNTQVLALE--GGRYRVFGETLDIGIGNAIDVFARELGLGFPG 171
           + +   + + V L VSGG+T +L +   G      G T+D   G A D  AR LGLG+PG
Sbjct: 123 VYEHGPLPECVALLVSGGHTHLLHVRSLGEPIIELGSTVDDAAGEAYDKVARLLGLGYPG 182

Query: 172 GPKVEKLAEKGEK-YIELPYAVKG-----MDLSFSGLLTEAIRKYRSGK----YRVEDLA 221
           G  ++ LA  G++  I  P  + G        SFSGL T   R   S      +R  D+A
Sbjct: 183 GKALDDLARTGDRDAIVFPRGMSGPADDRYAFSFSGLKTAVARYVESHAADPGFRTADIA 242

Query: 222 YSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYD 281
             FQE     L     RA        +++ GGVAAN+RLRE+      + G    +P   
Sbjct: 243 AGFQEAVADVLTMKAVRAATALGVSTLLIAGGVAANSRLRELATQRCGEAGRTLRIPSPR 302

Query: 282 LCRDNGAMIAYTGLRMYKAG 301
           LC DNGAMIA    ++  AG
Sbjct: 303 LCTDNGAMIAAFAAQLVAAG 322


>sp|P57166|GCP_BUCAI PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROTEASE)
           >gi|10038746|dbj|BAB12781.1| (AP001118)
           O-sialoglycoprotein endopeptidase [Buchnera sp. APS]
           Length = 336
           
 Score =  143 bits (357), Expect = 3e-33
 Identities = 111/337 (32%), Positives = 173/337 (50%), Gaps = 20/337 (5%)

Query: 1   MLALGIEGTAHTLGIGIVSEDK--VLANVFDT--LTTEKGGIHPKEAAEHHARLMKPLLR 56
           M  LGIE +    GI I   +K  ++  +++   L    GGI P+ A+  H   M  LL 
Sbjct: 1   MRILGIETSCDDTGIAIYDTNKGLLINEIYNQRKLNNIYGGIIPELASREHMEAMIVLLN 60

Query: 57  KALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITK 116
           K   +  +    +D+IA++ GPGL  +L V AT A +L +    P++ V+H  AH+ ++ 
Sbjct: 61  KIFKKKNI-YKYVDMIAYTAGPGLIGSLLVGATFACSLGLSLNIPVLPVHHMEAHL-LSP 118

Query: 117 MFGVKDP----VGLYVSGGNTQVL-ALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPG 171
           M   K      +GL VSG +TQ++ A + G Y + G  LD   G A D  A+ LGL +PG
Sbjct: 119 MLDYKTIQFPFIGLLVSGKHTQIIGAHKFGEYEILGNCLDDAAGEAFDKTAKLLGLKYPG 178

Query: 172 GPKVEKLAEKGEK-YIELPYAV---KGMDLSFSGLLT---EAIRKYRSGKYRVEDLAYSF 224
           G ++ KLA KG K Y   P  +     ++ SFSGL T   + I+K         ++A +F
Sbjct: 179 GLELSKLASKGIKDYFYFPRPMIHHSDLNFSFSGLKTFAAQTIKKSSKSMQEKANIAKAF 238

Query: 225 QETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDR-GIKFFVPPYDLC 283
           ++     L+  T++A+   +   +V+ GGV+AN +LR+   IM +       F    + C
Sbjct: 239 EDAVIDILLIKTKKALKKQKWKRLVIAGGVSANQKLRKKSEIMVKKNFNGTVFYSSLEFC 298

Query: 284 RDNGAMIAYTGLRMYKAGISFRLEETIVKQKFRTDEV 320
            DN AMIAY G    K   + +L E +VK K+  D++
Sbjct: 299 TDNAAMIAYLGSLRQKEARNSQL-EILVKPKWSIDDL 334


>gb|AAF73560.1| (AE002315) O-sialoglycoprotein endopeptidase [Chlamydia muridarum]
           Length = 340
           
 Score =  143 bits (356), Expect = 4e-33
 Identities = 100/318 (31%), Positives = 157/318 (48%), Gaps = 23/318 (7%)

Query: 1   MLALGIEGTAHTLGIGIVSEDKVLAN--VFDTLTTEKGGIHPKEAAEHHARLMKPLLRKA 58
           ML LG+E +       +V   K+LAN      +    GG+ P+ A+  H ++   LL   
Sbjct: 1   MLTLGLESSCDETSCALVENGKILANRIASQDIHAAYGGVIPELASRAHLQIFPKLLAAV 60

Query: 59  LSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKMF 118
             +A VSL+D+++I+ +  PGL  AL V    A+ LA   +K ++GVNH  AH+    + 
Sbjct: 61  AQDAEVSLEDVELISVANTPGLIGALSVGVNFAKGLASGLKKTLIGVNHVEAHLYAACLE 120

Query: 119 --GVKDP-VGLYVSGGNTQVLALEGG-RYRVFGETLDIGIGNAIDVFARELGLGFPGGPK 174
              ++ P +GL +SG +T +  +     + + G+T D  IG   D  AR LGL +PGG K
Sbjct: 121 EPSIRFPALGLAISGAHTSLFLMPNATTFLLIGKTRDDAIGETFDKVARFLGLPYPGGQK 180

Query: 175 VEKLAEKG--EKYIELPYAVKGMDLSFSGLLTEAIRKYRS------------GKYRVEDL 220
           +E+LA+ G  E Y      V G D SFSGL T  +   +              + +  ++
Sbjct: 181 LEELAQDGDEEAYPFSRAKVSGNDFSFSGLKTAVLYALKGNNSSAKAPFPEVSETQKRNI 240

Query: 221 AYSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPY 280
           A SFQ+ AF  + +     V     + +++ GGVA N   R   R++ +   +  + P  
Sbjct: 241 AASFQKAAFMTIAQKLPDIVKAFSCESLIVGGGVANNRYFR---RLLNQTCSLPTYFPSS 297

Query: 281 DLCRDNGAMIAYTGLRMY 298
            LC DN AMIA  G R++
Sbjct: 298 QLCSDNAAMIAGLGERLF 315


>sp|Q9ZEA8|GCP_RICPR PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROTEASE)
           >gi|7444723|pir||E71711 probable o-sialoglycoprotein
           endopeptidase (gcp) RP037 - Rickettsia prowazekii
           >gi|3860607|emb|CAA14508.1| (AJ235270) PROBABLE
           O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (gcp) [Rickettsia
           prowazekii]
           Length = 387
           
 Score =  141 bits (352), Expect = 1e-32
 Identities = 112/363 (30%), Positives = 164/363 (44%), Gaps = 69/363 (19%)

Query: 4   LGIEGTAHTLGIGIVSED-KVLANVFDTLTTEK---GGIHPKEAAEHHARLMKPLLRKAL 59
           LGIE +     I I++E  K+L+N+  +  TE    GG+ P+ AA  H   +   L+  L
Sbjct: 5   LGIESSCDDTAISIITERRKILSNIIISQNTEHAVFGGVVPEIAARSHLSNLDQALKNVL 64

Query: 60  SEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKMF- 118
            ++   L +I  IA + GPGL   + V +  AR+L+   +KP + +NH   H    ++  
Sbjct: 65  KKSNTELTEISAIAATSGPGLIGGVIVGSMFARSLSSALKKPFIAINHLEGHALTARLTD 124

Query: 119 GVKDP-VGLYVSGGNTQVLALEG-GRYRVFGETLDIGIGNAIDVFARELGLGFPGGPKVE 176
            +  P + L  SGG+ Q +A+ G G+Y++ G T+D  +G   D  A+ L L FPGGP++E
Sbjct: 125 NISYPYLLLLASGGHCQFVAVLGLGKYKILGTTIDDAVGETFDKVAKMLNLSFPGGPEIE 184

Query: 177 KLAEKGEKY-IELPYAV---KGMDLSFSGLLTEAIRKYRSGKYRV-----EDLAYSFQET 227
           K A+ G  +  + P  +      ++SFSGL T A+R        V      D+A SFQ T
Sbjct: 185 KRAKLGNPHKYKFPKPIINSGNCNMSFSGLKT-AVRTLIMNLKEVNDSVINDIAASFQFT 243

Query: 228 AFAALVEVTERAVA--------------HTEK---------------------------- 245
             A L    + A+               H  K                            
Sbjct: 244 IGAILSSKMQDAIRLYKQILNDYYEDINHPTKLNLKSFRKDEFNWKPLECITRPKYRIHI 303

Query: 246 ----------DEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGL 295
                     D +V+ GGVAAN  L+E+L   T   G +   PP  LC DN AMIAY GL
Sbjct: 304 QNSYRSNLLNDTIVIAGGVAANKYLQEILSDCTRPYGYRLIAPPMHLCTDNAAMIAYAGL 363

Query: 296 RMY 298
             Y
Sbjct: 364 ERY 366


>sp|P37969|GCP_MYCLE PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROTEASE)
           >gi|2145944|pir||S72817 probable glycoproteinase -
           Mycobacterium leprae >gi|466938|gb|AAC43226.1| (U00015)
           u1620c; B1620_C3_226 [Mycobacterium leprae]
           Length = 351
           
 Score =  133 bits (332), Expect = 2e-30
 Identities = 108/310 (34%), Positives = 153/310 (48%), Gaps = 20/310 (6%)

Query: 2   LALGIEGTAHTLGIGIVSEDK-----VLANVFDTLTTEK---GGIHPKEAAEHHARLMKP 53
           + L IE +    G+GI   D      +LA+   +   E+   GG+ P+ A+  H   + P
Sbjct: 10  IILAIETSCDETGVGIACLDDYGTVTLLADEVASSVDEQARFGGVVPEIASRAHLEALGP 69

Query: 54  LLRKALSEAGVSLD-DIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHV 112
            +R AL+ AG++     DV+A + GPGL  AL V   AA+A +  +  P   VNH   H+
Sbjct: 70  TIRCALAAAGLTGSAKPDVVAATIGPGLAGALLVGVAAAKAYSAAWGVPFYAVNHLGGHL 129

Query: 113 --EITKMFGVKDPVGLYVSGGNTQVLALE--GGRYRVFGETLDIGIGNAIDVFARELGLG 168
             ++ +   + + V L VSGG+T +L +   G      G T+D   G A D  AR LGLG
Sbjct: 130 AADVYEHGPLPECVALLVSGGHTHLLQVRSLGAPIVELGSTVDDAAGEAYDKVARLLGLG 189

Query: 169 FPGGPKVEKLAEKGEK-YIELPYAVKGM--DL---SFSGLLTEAIRKYRSGKYRVE-DLA 221
           +PGG  ++ LA  G++  I  P  + G   DL   SFSGL T   R   S    +  D+A
Sbjct: 190 YPGGKVLDDLARTGDRDAIVFPRGMTGPADDLNAFSFSGLKTAVARYVESHPDALPADVA 249

Query: 222 YSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYD 281
             FQE     L     RA        +++VGGVAAN+RLRE+        G+   +P   
Sbjct: 250 AGFQEAVADVLTMKAVRAATGLGVSTLLIVGGVAANSRLRELAAQRCAAAGLMLRIPGPR 309

Query: 282 LCRDNGAMIA 291
            C DNGAMIA
Sbjct: 310 FCTDNGAMIA 319


>sp|O83686|GCP_TREPA PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROTEASE)
           >gi|7444717|pir||H71294 probable o-sialoglycoprotein
           endopeptidase (gcp) - syphilis spirochete
           >gi|3322977|gb|AAC65643.1| (AE001242)
           o-sialoglycoprotein endopeptidase (gcp) [Treponema
           pallidum]
           Length = 352
           
 Score =  125 bits (312), Expect = 5e-28
 Identities = 105/317 (33%), Positives = 151/317 (47%), Gaps = 27/317 (8%)

Query: 1   MLALGIEGTAHTLGIGIVSEDK-VLANVFDT---LTTEKGGIHPKEAAEHHARLMKPLLR 56
           M  LGIE +     + IV +   V +NV  T         GI P+ A+  H   + P ++
Sbjct: 1   MNVLGIETSCDETAVAIVKDGTHVCSNVVATQIPFHAPYRGIVPELASRKHIEWILPTVK 60

Query: 57  KALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNH-----CIAH 111
           +AL+ A ++L DID IA +  PGL  +L V  T A+ LA     P + VNH     C AH
Sbjct: 61  EALARAQLTLADIDGIAVTHAPGLTGSLLVGLTFAKTLAWSMHLPFIAVNHLHAHFCAAH 120

Query: 112 VEITKMFGVKDPVGLYVSGGNTQVLAL-EGGRYRVFGETLDIGIGNAIDVFARELGLGFP 170
           VE    +     VGL  SGG+  V  + +  +    G T+D   G A D  A   G G+P
Sbjct: 121 VEHDLAYPY---VGLLASGGHALVCVVHDFDQVEALGATIDDAPGEAFDKVAAFYGFGYP 177

Query: 171 GGPKVEKLAEKGE---KYIELP-YAVKG--MDLSFSGLLTEAIRKY-----RSGKYRVED 219
           GG  +E LAE+G+       LP +  KG   D+S+SGL T  I +      +  +   ++
Sbjct: 178 GGKVIETLAEQGDARAARFPLPHFHGKGHRYDVSYSGLKTAVIHQLDHFWNKEYERTAQN 237

Query: 220 LAYSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPP 279
           +A +FQ  A   L+    RA+  T     V+ GGVAAN+ LR+ +      R +    P 
Sbjct: 238 IAAAFQACAINILLRPLARALQDTGLPTAVVCGGVAANSLLRKSVADWKHARCV---FPS 294

Query: 280 YDLCRDNGAMIAYTGLR 296
            + C DN  M+A  G R
Sbjct: 295 REYCTDNAVMVAALGYR 311


>gi|6320099 similar to H.influenzae sialoglycoprotease; Qri7p [Saccharomyces
           cerevisiae] >gi|1172805|sp|P43122|QRI7_YEAST PUTATIVE
           PROTEASE QRI7 >gi|1077467|pir||S50740 QRI7 protein -
           yeast (Saccharomyces cerevisiae)
           >gi|683704|emb|CAA55926.1| (X79380) QRI7 [Saccharomyces
           cerevisiae] >gi|1199545|emb|CAA64909.1| (X95644) ORF
           2358 [Saccharomyces cerevisiae]
           >gi|1431146|emb|CAA98671.1| (Z74152) ORF YDL104c
           [Saccharomyces cerevisiae]
           Length = 407
           
 Score =  124 bits (309), Expect = 1e-27
 Identities = 103/324 (31%), Positives = 163/324 (49%), Gaps = 54/324 (16%)

Query: 23  VLANVFDTLTT-EKGGIHPKEAAEHHARLMKPLLRKALSEAGVSLDDIDVIAFSQGPGLG 81
           VLAN+ DTL + ++GGI P +A  HH   + PL  +AL E+    + ID+I  ++GPG+ 
Sbjct: 61  VLANLKDTLDSIDEGGIIPTKAHIHHQARIGPLTERALIESNAR-EGIDLICVTRGPGMP 119

Query: 82  PALRVVATAARALAVKYRKPIVGVNHCIAHVEITKM-FGVKDP----VGLYVSGGNTQ-V 135
            +L      A+ LAV + KP++GV+H + H+ I +M    K P    V L VSGG+T  V
Sbjct: 120 GSLSGGLDFAKGLAVAWNKPLIGVHHMLGHLLIPRMGTNGKVPQFPFVSLLVSGGHTTFV 179

Query: 136 LALEGGRYRVFGETLDIGIGNAIDVFARELGLGFPGGPKVEKLAEKGEKYI--------- 186
           L+     + +  +T+DI +G+++D   RELG       K   +A + EK+I         
Sbjct: 180 LSRAIDDHEILCDTIDIAVGDSLDKCGRELGF------KGTMIAREMEKFINQDINDQDF 233

Query: 187 ----ELPYAVKG-------MDLSFSGLLTEAIRK--YRSGKYRVEDL--------AYSFQ 225
               E+P  +K        +  SFS  +T A+R    + GK  +++L        AY  Q
Sbjct: 234 ALKLEMPSPLKNSASKRNMLSFSFSAFIT-ALRTNLTKLGKTEIQELPEREIRSIAYQVQ 292

Query: 226 ETAFAALVEVTERAV-AHTEK----DEVVLVGGVAANNRLREMLR----IMTEDRGIKFF 276
           E+ F  ++   +  + +  EK     E V  GGV++N RLR  L      +       F+
Sbjct: 293 ESVFDHIINKLKHVLKSQPEKFKNVREFVCSGGVSSNQRLRTKLETELGTLNSTSFFNFY 352

Query: 277 VPPYDLCRDNGAMIAYTGLRMYKA 300
            PP DLC DN  MI + G+ ++++
Sbjct: 353 YPPMDLCSDNSIMIGWAGIEIWES 376


>sp|P75055|GCP_MYCPN PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROTEASE)
           >gi|2146478|pir||S73421 o-sialoglycoprotein
           endopeptidase - Mycoplasma pneumoniae  (strain ATCC
           29342) >gi|1673750|gb|AAB95743.1| (AE000011)
           o-sialoglycoprotein endopeptidase [Mycoplasma
           pneumoniae]
           Length = 319
           
 Score =  123 bits (306), Expect = 3e-27
 Identities = 95/312 (30%), Positives = 153/312 (48%), Gaps = 34/312 (10%)

Query: 4   LGIEGTAHTLGIGIVSEDKVLANVFDT---LTTEKGGIHPKEAAEHHARLMKPLLRKALS 60
           LGIE T     IG+++E KV A++  +   L  + GG+ P+ AA  H +     L KAL 
Sbjct: 8   LGIETTCDDTSIGVITESKVQAHIVLSSAKLHAQTGGVVPEVAARSHEQN----LLKALQ 63

Query: 61  EAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHV-------E 113
           ++GV L+ I  IA++  PGL   L V AT AR+L+    KP++ +NH  AH+       +
Sbjct: 64  QSGVVLEQITHIAYAANPGLPGCLHVGATFARSLSFLLDKPLLPINHLYAHIFSALIDQD 123

Query: 114 ITKMFGVKDP-VGLYVSGGNTQVLALEG-GRYRVFGETLDIGIGNAIDVFARELGLGFPG 171
           I ++   K P +GL VSGG+T +  ++      +  ET D  IG   D   R +G  +P 
Sbjct: 124 INQL---KLPALGLVVSGGHTAIYLIKSLFDLELIAETSDDAIGEVYDKVGRAMGFPYPA 180

Query: 172 GPKVEKL--AEKGEKYIELPYAVKGMDLSFSGLLTEAIRKYRSGKYRV---------EDL 220
           GP+++ L   E  + +     + K    S+SGL ++   K +  + R           + 
Sbjct: 181 GPQLDSLFQPELVKSHYFFRPSTKWTKFSYSGLKSQCFTKIKQLRERKGFNPQTHDWNEF 240

Query: 221 AYSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPY 280
           A +FQ T     +   + A+   +   ++L GGV+AN  LRE +  +     + + + P 
Sbjct: 241 ASNFQATIIDHYINHVKDAIQQHQPQMLLLGGGVSANKYLREQVTQLQ----LPYLIAPL 296

Query: 281 DLCRDNGAMIAY 292
               DNGAMI +
Sbjct: 297 KYTSDNGAMIGF 308


>sp|P47292|GCP_MYCGE PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROTEASE)
           >gi|1361848|pir||A64205 O-sialoglycoprotein
           endopeptidase (EC 3.4.24.57) homolog - Mycoplasma
           genitalium >gi|3844655|gb|AAC71262.1| (U39684)
           O-sialoglycoprotein endopeptidase [Mycoplasma
           genitalium]
           Length = 315
           
 Score =  115 bits (284), Expect = 1e-24
 Identities = 86/310 (27%), Positives = 150/310 (47%), Gaps = 28/310 (9%)

Query: 1   MLALGIEGTAHTLGIGIVSEDKVLANVFDT---LTTEKGGIHPKEAAEHHARLMKPLLRK 57
           +  LGIE T    G+ IV + K+ +N+  +   L  + GG+ P+ AA  H +     L K
Sbjct: 5   LCVLGIETTCDDTGLSIVIDQKIKSNIVISSANLHVKTGGVVPEIAARCHEQN----LFK 60

Query: 58  ALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHV----- 112
           A+ +    + D+  IA++  PGL   L V AT AR+L+    KP++ +NH  AH+     
Sbjct: 61  AIRDLNFEIRDLSHIAYACNPGLAGCLHVGATFARSLSFLLDKPLLPINHLYAHIFSCLI 120

Query: 113 --EITKMFGVKDPVGLYVSGGNTQVLALEG-GRYRVFGETLDIGIGNAIDVFARELGLGF 169
             ++ K+      +GL +SGG+T +  ++      +  ET D  IG   D   R +G  +
Sbjct: 121 DQDLNKL--QLPALGLVISGGHTAIYLVKSFYELELIAETSDDAIGEVYDKIGRAMGFDY 178

Query: 170 PGGPKVEKLAEKG--EKYIELPYAVKGMDLSFSGLLTEAIRKYR---SGKYRVE--DLAY 222
           P G K++ L  K   + +     + K    S+SGL ++ + K +   + K R++  +LA 
Sbjct: 179 PAGSKIDSLFNKELVKPHYFFKPSTKWTKFSYSGLKSQCLNKIKQISANKTRIDWSELAS 238

Query: 223 SFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDL 282
           +FQ T     ++  + A+       +++ GGV+AN+ L   +  +     + F +     
Sbjct: 239 NFQATIIDHYIDHVKNAIKKFAPKMLLVGGGVSANSYLSNRISTL----NLPFLIADSKY 294

Query: 283 CRDNGAMIAY 292
             DNGAMI +
Sbjct: 295 TSDNGAMIGF 304


>pir||S72996 probable glycoproteinase u229e - Mycobacterium leprae
           >gi|467128|gb|AAA17310.1| (U00020) u229e; B229_C3_246
           [Mycobacterium leprae]
           Length = 290
           
 Score =  112 bits (277), Expect = 6e-24
 Identities = 95/278 (34%), Positives = 137/278 (49%), Gaps = 20/278 (7%)

Query: 2   LALGIEGTAHTLGIGIVSEDK-----VLANVFDTLTTEK---GGIHPKEAAEHHARLMKP 53
           + L IE +    G+GI   D      +LA+   +   E+   GG+ P+ A+  H   + P
Sbjct: 10  IILAIETSCDETGVGIACLDDYGTVTLLADEVASSVDEQARFGGVVPEIASRAHLEALGP 69

Query: 54  LLRKALSEAGVSLD-DIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHV 112
            +R AL+ AG++     DV+A + GPGL  AL V   AA+A +  +  P   VNH   H+
Sbjct: 70  TIRCALAAAGLTGSAKPDVVAATIGPGLAGALLVGVAAAKAYSAAWGVPFYAVNHLGGHL 129

Query: 113 --EITKMFGVKDPVGLYVSGGNTQVLALE--GGRYRVFGETLDIGIGNAIDVFARELGLG 168
             ++ +   + + V L VSGG+T +L +   G      G T+D   G A D  AR LGLG
Sbjct: 130 AADVYEHGPLPECVALLVSGGHTHLLQVRSLGAPIVELGSTVDDAAGEAYDKVARLLGLG 189

Query: 169 FPGGPKVEKLAEKGEK-YIELPYAVKGM--DL---SFSGLLTEAIRKYRSGKYRV-EDLA 221
           +PGG  ++ LA  G++  I  P  + G   DL   SFSGL T   R   S    +  D+A
Sbjct: 190 YPGGKVLDDLARTGDRDAIVFPRGMTGPADDLNAFSFSGLKTAVARYVESHPDALPADVA 249

Query: 222 YSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNR 259
             FQE     L     RA        +++VGGVAAN+R
Sbjct: 250 AGFQEAVADVLTMKAVRAATGLGVSTLLIVGGVAANSR 287


>gi|11641265 putative sialoglycoprotease type 2 [Homo sapiens]
           >gi|11071727|emb|CAC14666.1| (AJ295148) putative
           sialoglycoprotease type 2 [Homo sapiens]
           Length = 439
           
 Score =  110 bits (273), Expect = 2e-23
 Identities = 101/363 (27%), Positives = 166/363 (44%), Gaps = 62/363 (17%)

Query: 2   LALGIEGTAHTLGIGIVSED-KVLANVFDTLTT---EKGGIHPKEAAEHHARLMKPLLRK 57
           + LGIE +       +V E   VL     + T    + GGI P  A + H   ++ ++++
Sbjct: 38  IVLGIETSCDDTAAAVVDETGNVLGEAIHSQTEVHLKTGGIVPPAAQQLHRENIQRIVQE 97

Query: 58  ALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKM 117
           ALS +GVS  D+  IA +  PGL  +L V  + +  L  + +KP + ++H  AH    ++
Sbjct: 98  ALSASGVSPSDLSAIATTIKPGLALSLGVGLSFSLQLVGQLKKPFIPIHHMEAHALTIRL 157

Query: 118 FG-VKDP-VGLYVSGGNTQVLALEG-GRYRVFGETLDIGIGNAIDVFARELGL------- 167
              V+ P + L +SGG+  +  ++G   + + G++LDI  G+ +D  AR L L       
Sbjct: 158 TNKVEFPFLVLLISGGHCLLALVQGVSDFLLLGKSLDIAPGDMLDKVARRLSLIKHPECS 217

Query: 168 GFPGGPKVEKLAEKGEKY---IELP-YAVKGMDLSFSGL--LTEAI-------------- 207
              GG  +E LA++G ++   I+ P +  K  D SF+GL  +T+ I              
Sbjct: 218 TMSGGKAIEHLAKQGNRFHFDIKPPLHHAKNCDFSFTGLQHVTDKIIMKKEKEEGIFLIS 277

Query: 208 ------------------RKYRSGKY--RVEDLAYSFQETAFAALVEVTERAVAHTEKDE 247
                              +Y  G+      D+A + Q T    LV+ T RA+   ++ +
Sbjct: 278 KVEQINIPGLCLKIAAHFCRYEKGQILSSAADIAATVQHTMACHLVKRTHRAILFCKQRD 337

Query: 248 --------VVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGLRMYK 299
                   +V  GGVA+N  +R  L I+T         PP  LC DNG MIA+ G+   +
Sbjct: 338 LLPQNNAVLVASGGVASNFYIRRALEILTNATQCTLLCPPPRLCTDNGIMIAWNGIERLR 397

Query: 300 AGI 302
            G+
Sbjct: 398 GGL 400


>pir||T40899 probable proteinase - fission yeast (Schizosaccharomyces pombe)
           >gi|4049543|emb|CAA22548.1| (AL034564) putative
           protease; endopeptidase [Schizosaccharomyces pombe]
           Length = 412
           
 Score =  109 bits (269), Expect = 6e-23
 Identities = 88/297 (29%), Positives = 140/297 (46%), Gaps = 32/297 (10%)

Query: 36  GGIHPKEAAEHHARLMKPLLRKALSEAGVS-LDDIDVIAFSQGPGLGPALRVVATAARAL 94
           GGIHP      H + +  ++++ +S+A  S + D D+IA ++GPG+   L V    A+ L
Sbjct: 85  GGIHPTIVIHEHQKNLAKVIQRTISDAARSGITDFDLIAVTRGPGMIGPLAVGLNTAKGL 144

Query: 95  AVKYRKPIVGVNHCIAH---VEITKMFGVKDPVGLYVSGGNTQVLALEG-GRYRVFGETL 150
           AV  +KP++ V+H  AH   V++ K       + + VSGG+T ++       + +   T 
Sbjct: 145 AVGLQKPLLAVHHMQAHALAVQLEKSIDF-PYLNILVSGGHTMLVYSNSLLNHEIIVTTS 203

Query: 151 DIGIGNAIDVFARELGLGFPGGPKVEKLAEKGEKYI-ELPYAVK------------GMDL 197
           DI +G+ +D  A+ LG+ +        L +     I    Y++K                
Sbjct: 204 DIAVGDYLDKCAKYLGIPWDNEMPAAALEQFASPEINSTSYSLKPPIPLNTREKVHSASF 263

Query: 198 SFSGLLTEAIRKYRSGKYRVED---LAYSFQETAFAALVEVTERAVAHTEKDEV---VLV 251
           SFSGL + A R  R     + +    AY  Q  AF  + + T  A+   +  +V   V  
Sbjct: 264 SFSGLESYACRIIRKTPLNLSEKKFFAYQLQYAAFQHICQKTLLALKRLDLSKVKYLVCS 323

Query: 252 GGVAANNRLREM-------LRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGLRMYKAG 301
           GGVA N  L++M       L+   +   IK   P  D+C DN AMI YT ++M+KAG
Sbjct: 324 GGVARNELLKKMLNDTLMVLQFEHQPTDIKLVYPSPDICSDNAAMIGYTAIQMFKAG 380


>pir||T18825 hypothetical protein C01G10.10 - Caenorhabditis elegans
           >gi|3873878|emb|CAB02716.1| (Z81030) contains similarity
           to Pfam domain: PF00814 (Glycoprotease family),
           Score=577.5, E-value=2.8e-170, N=1~cDNA EST yk113e2.3
           comes from this gene~cDNA EST yk113e2.5 comes from this
           gene~cDNA EST yk342g8.3 comes from this gene~cDNA EST
           yk342g8.5 c>
           Length = 421
           
 Score =  103 bits (254), Expect = 3e-21
 Identities = 93/326 (28%), Positives = 155/326 (47%), Gaps = 34/326 (10%)

Query: 4   LGIEGTAHTLGIGIVSEDKVLAN----VFDTLTTEKGGIHPKEAAEHHARLMKPLLRKAL 59
           LGIE +     + IV+E + + +        +  ++GGI+P   A  H   +  L+ K L
Sbjct: 26  LGIETSCDDTAVAIVNEKREILSSERYTERAIQRQQGGINPSVCALQHRENLPRLIEKCL 85

Query: 60  SEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKMFG 119
           ++AG S  D+D +A +  PGL  AL+   +AA   A K+R P++ V+H  AH     +  
Sbjct: 86  NDAGTSPKDLDAVAVTVTPGLVIALKEGISAAIGFAKKHRLPLIPVHHMRAHA--LSILL 143

Query: 120 VKDPV-----GLYVSGGNTQV-LALEGGRYRVFGETLDIGIGNAIDVFARELG-LG--FP 170
           V D V      + +SGG+  + +A +  +++++G+++    G  ID  AR+LG LG  F 
Sbjct: 144 VDDSVRFPFSAVLLSGGHALISVAEDVEKFKLYGQSVSGSPGECIDKVARQLGDLGSEFD 203

Query: 171 G---GPKVEKLAEKGEKYIELPYA-----VKGMDLSFSGL------LTEAIRKYRSGKYR 216
           G   G  VE LA +      L Y      V   +++F  +      L E +RK       
Sbjct: 204 GIHVGAAVEILASRASADGHLRYPIFLPNVPKANMNFDQIKGSYLNLLERLRKNSETSID 263

Query: 217 VEDLAYSFQETA---FAALVEVTERAVAHTEK--DEVVLVGGVAANNRLREMLRIMTEDR 271
           + D   S Q T     ++ + +   +++  EK   ++V+ GGVAAN  +   +  ++   
Sbjct: 264 IPDFCASLQNTVARHISSKLHIFFESLSEQEKLPKQLVIGGGVAANQYIFGAISKLSAAH 323

Query: 272 GIKFFVPPYDLCRDNGAMIAYTGLRM 297
            +        LC DN  MIAY+GL M
Sbjct: 324 NVTTIKVLLSLCTDNAEMIAYSGLLM 349


>pir||H82894 sialoglycoproteinase UU411 [imported] - Ureaplasma urealyticum
           >gi|6899399|gb|AAF30822.1|AE002138_9 (AE002138)
           sialoglycoprotease [Ureaplasma urealyticum]
           Length = 320
           
 Score =  101 bits (249), Expect = 1e-20
 Identities = 87/321 (27%), Positives = 152/321 (47%), Gaps = 29/321 (9%)

Query: 2   LALGIEGTAHTLGIGIVSEDKVLANVFDT---LTTEKGGIHPKEAAEHHARLMKPLLRKA 58
           L L IE +     + +   +K++A+   +   + +  GG+ P+ A+ +H + +  L  + 
Sbjct: 6   LILSIESSCDETSLALFENNKLIAHKISSSASIQSLHGGVVPELASRYHEQNINHLFNEI 65

Query: 59  LSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHV------ 112
           L+E  ++   I  +A++  PGL   L V    A+ LAV     +V +NH  AHV      
Sbjct: 66  LNETKINPLTITHVAYTAMPGLPGCLHVGKVFAKQLAVLINAELVPINHLHAHVFSASIN 125

Query: 113 -EITKMFGVKDPVGLYVSGGNTQV-LALEGGRYRVFGETLDIGIGNAIDVFARELGLGFP 170
             +T  F     +GL VSGG + + L  +    +V  +T D  IG   D  AR LG  +P
Sbjct: 126 QNLTFPF-----LGLVVSGGESCIYLVNDYDEIKVLNQTHDDAIGECYDKIARVLGWKYP 180

Query: 171 GGPKVEKLAEKGEKYIE-LPYAVKGMDLSFSGLLTEAIRKYRSGKYRVED-----LAYSF 224
           GGP ++K  ++    +E +       D SFSGL T  I    + K +        +A SF
Sbjct: 181 GGPIIDKNYQENLATLEFIKSQPAAKDFSFSGLKTAVINYIHNAKQKKISFDPVVVASSF 240

Query: 225 QETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCR 284
           Q+ A   +++  +  +   + + + + GGV+AN+ LR+ ++ +     +  ++P      
Sbjct: 241 QKFAINEIIKKIKYYLNLYKLNHLAIGGGVSANSLLRKKIQSL----DVISYIPEMIYTG 296

Query: 285 DNGAMI---AYTGLRMYKAGI 302
           DN AMI   AY  ++ +K  I
Sbjct: 297 DNAAMIGAYAYALIKNHKKSI 317


>pir||E81278 probable glycoproteinase Cj1344c [imported] - Campylobacter jejuni
           (strain NCTC 11168) >gi|6968778|emb|CAB73771.1|
           (AL139078) putative glycoprotease [Campylobacter jejuni]
           Length = 335
           
 Score = 99.1 bits (243), Expect = 6e-20
 Identities = 86/334 (25%), Positives = 147/334 (43%), Gaps = 30/334 (8%)

Query: 2   LALGIEGTAHTLGIGIVSEDKVLANVFDTLTTEK-----GGIHPKEAAEHHARLMKPLLR 56
           L L IE +     I I+ ++ +       ++ E      GG+ P+ AA  H+  +  +L+
Sbjct: 4   LILAIESSCDDSSIAIIDKNTLECKFHKKISQELDHSIYGGVVPELAARLHSEALPKMLK 63

Query: 57  KALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHV---- 112
           +          ++  IA +  PGL  +L    + A+ LA     P++ +NH   H+    
Sbjct: 64  QCKEH----FKNLCAIAVTNEPGLSVSLLSGISMAKTLASALNLPLIPINHLKGHIYSLF 119

Query: 113 ---EITKMFGVKDPVGLYVSGGNTQVLAL-EGGRYRVFGETLDIGIGNAIDVFARELGLG 168
              +I+   G+     L VSGG+T VL L +     +   T D   G + D  A+ + LG
Sbjct: 120 LEEKISLDMGI-----LLVSGGHTMVLYLKDDASLELLASTNDDSFGESFDKVAKMMNLG 174

Query: 169 FPGGPKVEKLAEKGE-KYIELPYAVKG---MDLSFSGLLT----EAIRKYRSGKYRVEDL 220
           +PGG  +E LA+  + K I     +K    +  SFSGL      E ++     +    ++
Sbjct: 175 YPGGVIIENLAKNAKLKNISFNTPLKHSKELAFSFSGLKNAVRLEILKHENLNEDTKAEI 234

Query: 221 AYSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPY 280
           AY+F+ TA   +++  E+     +     +VGG +AN  LR  L+ + +       + P 
Sbjct: 235 AYAFENTACDHIMDKLEKIFNLYKFKNFGVVGGASANLNLRSRLQNLCQKYNANLKLAPL 294

Query: 281 DLCRDNGAMIAYTGLRMYKAGISFRLEETIVKQK 314
             C DN  MIA   +  Y+      +EE I+  K
Sbjct: 295 KFCSDNALMIARAAVDAYEKKEFVSVEEDILSPK 328


>gb|AAF49008.1| (AE003513) CG14231 gene product [Drosophila melanogaster]
           Length = 409
           
 Score = 97.1 bits (238), Expect = 2e-19
 Identities = 94/336 (27%), Positives = 148/336 (43%), Gaps = 46/336 (13%)

Query: 4   LGIEGTAHTLGIGIV-SEDKVLANVFDT---LTTEKGGIHPKEAAEHHARLMKPLLRKAL 59
           LGIE +    GI IV +  +V+ANV ++     T  GGI P  A + H   ++   ++ +
Sbjct: 28  LGIETSCDDTGIAIVDTTGRVIANVLESQQEFHTRYGGIIPPRAQDLHRARIESAYQRCM 87

Query: 60  SEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKMFG 119
             A +  D +  IA +  PGL  +L V    AR LA + +KP++ V+H  AH    +M  
Sbjct: 88  EAAQLKPDQLTAIAVTTRPGLPLSLLVGVRFARHLARRLQKPLLPVHHMEAHALQARM-E 146

Query: 120 VKDPVG-----LYVSGGNTQVLALEG-GRYRVFGETLDIGIGNAIDVFARELGLG----- 168
             + +G     L  SGG+ Q++   G GR  + G+TLD   G A D   R L L      
Sbjct: 147 HPEQIGYPFLCLLASGGHCQLVVANGPGRLTLLGQTLDDAPGEAFDKIGRRLRLHILPEY 206

Query: 169 --FPGGPKVEKLAEKGEKYI----ELPYA-VKGMDLSFSGLLTEAIRKYRSGKYRVE--- 218
             + GG  +E  A+     +     LP A  +  + SF+G+   + R  R+ + R E   
Sbjct: 207 RLWNGGRAIEHAAQLASDPLAYEFPLPLAQQRNCNFSFAGIKNNSFRAIRA-RERAERTP 265

Query: 219 ---------DLAYSFQETAFAALVEVTERAVAH----------TEKDEVVLVGGVAANNR 259
                    D       +    L+  T+RA+ +               +V+ GGVA N+ 
Sbjct: 266 PDGVISNYGDFCAGLLRSVSRHLMHRTQRAIEYCLLPHRQLFGDTPPTLVMSGGVANNDA 325

Query: 260 LREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGL 295
           +   +  +    G + F P    C DNG MIA+ G+
Sbjct: 326 IYANIEHLAAQYGCRSFRPSKRYCSDNGVMIAWHGV 361


>pir||E71801 probable o-sialoglycoprotein endopeptidase - Helicobacter pylori
           (strain J99) >gi|4156114|gb|AAD07065.1| (AE001570)
           putative O-SIALOGLYCOPROTEIN ENDOPEPTIDASE [Helicobacter
           pylori J99]
           Length = 340
           
 Score = 94.8 bits (232), Expect = 1e-18
 Identities = 78/294 (26%), Positives = 127/294 (42%), Gaps = 15/294 (5%)

Query: 36  GGIHPKEAAEHHARLMKPLLRKALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALA 95
           GG+ P+ A+  HA  +  LL +           I  IA +  PGL   L      A+AL+
Sbjct: 40  GGVVPEIASRLHAENLPLLLERVKISLNKDFSKIKAIAITNQPGLSVTLIEGLMMAKALS 99

Query: 96  VKYRKPIVGVNHCIAHVE--ITKMFGVKDPVG-LYVSGGNTQVL-ALEGGRYRVFGETLD 151
           +    P++  +H   HV          + P+  L VSGG++ +L A +    ++   +LD
Sbjct: 100 LSLNLPLILEDHLRGHVYSLFINEKQTRMPLSVLLVSGGHSLILEARDYEDIKIVATSLD 159

Query: 152 IGIGNAIDVFARELGLGFPGGPKVEKLA---EKGEKYIELPYAVK---GMDLSFSGLLTE 205
              G + D  ++ L LG+PGGP VEKLA       + +  P  +K    +  SFSGL   
Sbjct: 160 DSFGESFDKVSKMLDLGYPGGPIVEKLALDYAHPNEPLMFPIPLKNSPNLAFSFSGLKNA 219

Query: 206 AIRKYRSGKYRVED-----LAYSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRL 260
              +     + + D     + Y FQ  A   L++ T+R           +VGG + N  L
Sbjct: 220 VRLEVEKNAHNLNDEVKQKIGYHFQSAAIEHLIQQTKRYFKIKRPKIFGIVGGASQNLAL 279

Query: 261 REMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGLRMYKAGISFRLEETIVKQK 314
           R+    +  +   +  + P + C DN AMI  + L  Y+      LE+  +  +
Sbjct: 280 RKAFEDLCAEFDCELVLAPLEFCSDNAAMIGRSSLEAYQKKRFIPLEKADISPR 333


>gb|AAD00282.1| (U78601) putative sialoglycoprotease protein [Streptococcus mutans]
           Length = 155
           
 Score = 94.0 bits (230), Expect = 2e-18
 Identities = 52/143 (36%), Positives = 82/143 (56%), Gaps = 3/143 (2%)

Query: 36  GGIHPKEAAEHHARLMKPLLRKALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALA 95
           GG+ PK A+ HH  ++   ++ AL EAG++  D+  +A + GPGL  AL V   AA+A A
Sbjct: 13  GGVVPKLASRHHVEVITLCIQDALQEAGITAGDLSAVAVTYGPGLVGALLVGMAAAKAFA 72

Query: 96  VKYRKPIVGVNHCIAHVEITKMFG-VKDP-VGLYVSGGNTQVLALEG-GRYRVFGETLDI 152
                P++ VNH   H+   +    ++ P + L VSGG+T+++ +   G YR+ GET D 
Sbjct: 73  WANHLPLIPVNHMAGHLMAAQSIADLQYPLLALLVSGGHTELVYVAAPGDYRIVGETRDN 132

Query: 153 GIGNAIDVFARELGLGFPGGPKV 175
            +G A D   R +GL +P G ++
Sbjct: 133 AVGEAYDKVGRVMGLTYPAGKEI 155


>sp|P55996|GCP_HELPY PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROTEASE)
           >gi|7444710|pir||H64717 sialoglycoproteinase gcp (EC
           3.4.-.-) - Helicobacter pylori  (strain 26695)
           >gi|2314767|gb|AAD08622.1| (AE000655) sialoglycoprotease
           (gcp) [Helicobacter pylori 26695]
           Length = 340
           
 Score = 92.8 bits (227), Expect = 5e-18
 Identities = 80/288 (27%), Positives = 123/288 (41%), Gaps = 33/288 (11%)

Query: 36  GGIHPKEAAEHHARLMKPLLRKALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALA 95
           GG+ P+ A+  HA  +  LL +           I  IA +  PGL   L      A+AL+
Sbjct: 40  GGVVPELASRLHAENLPLLLERIKISLNKDFSKIKAIAITNQPGLSVTLIEGLMMAKALS 99

Query: 96  VKYRKPIVGVNHCIAHVE---ITKMFGVKDPVGLYVSGGNTQVL-ALEGGRYRVFGETLD 151
           +    P++  +H   HV    I +         L VSGG++ +L A +    ++   +LD
Sbjct: 100 LSLNLPLILEDHLRGHVYSLFINEKQTCMPLSVLLVSGGHSLILEARDYENIKIVATSLD 159

Query: 152 IGIGNAIDVFARELGLGFPGGPKVEKLA---EKGEKYIELPYAVK---GMDLSFSGL--- 202
              G + D  ++ L LG+PGGP VEKLA       + +  P  +K    +  SFSGL   
Sbjct: 160 DSFGESFDKVSKMLDLGYPGGPIVEKLALDYRHPNEPLMFPIPLKNSPNLAFSFSGLKNA 219

Query: 203 -----------LTEAIRKYRSGKYRVEDLAYSFQETAFAALVEVTERAVAHTEKDEVVLV 251
                      L EAI+         + + Y FQ  A   L++ T+R           +V
Sbjct: 220 VRLEVEKNAPNLNEAIK---------QKIGYHFQSAAIEHLIQQTKRYFKIKRPKIFGIV 270

Query: 252 GGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGLRMYK 299
           GG + N  LR+    + +    K  + P + C DN AMI  + L  Y+
Sbjct: 271 GGASQNLALRKAFENLCDAFDCKLVLAPLEFCSDNAAMIGRSSLEAYQ 318


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.320    0.140    0.398 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 116600517
Number of Sequences: 2977
Number of extensions: 4927131
Number of successful extensions: 11084
Number of sequences better than 1.0e-10: 55
Number of HSP's better than  0.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 10892
Number of HSP's gapped (non-prelim): 57
length of query: 324
length of database: 189,106,746
effective HSP length: 56
effective length of query: 268
effective length of database: 155,591,474
effective search space: 41698515032
effective search space used: 41698515032
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 165 (68.7 bits)