BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB1171 (gcs1) DE:GLYCINE DEHYDROGENASE (DECARBOXYLATING)
SUBUNIT 1 (EC 1.4.4.2) (GLYCINE DECARBOXYLASE) (GLYCINE CLEAVAGE
SYSTEM P- PROTEIN).
         (449 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||E75030 probable glycine dehydrogenase (decarboxylating) (EC...   901  0.0
pir||C71216 probable glycine dehydrogenase subunit 1 - Pyrococcu...   857  0.0
gb|AAK41200.1| Glycine dehydrogenase subunit 1 [Sulfolobus solfa...   399  e-110
pir||G72518 probable glycine dehydrogenase subunit 1 APE2124 - A...   383  e-105
sp|P54376|GCS1_BACSU PROBABLE GLYCINE DEHYDROGENASE [DECARBOXYLA...   379  e-104
dbj|BAB06534.1| (AP001516) glycine dehydrogenase subunit 1 [Baci...   366  e-100
pir||G72403 glycine dehydrogenase (decarboxylating) subunit 1 - ...   347  1e-94
emb|CAC12479.1| (AL445067) glycine dehydrogenase (decarboxylatin...   327  2e-88
pir||F70395 glycine dehydrogenase (decarboxylating) - Aquifex ae...   323  3e-87
gb|AAG19868.1| (AE005071) glycine dehydrogenase subunit 1; GcvP1...   284  1e-75
sp|O49954|GCSP_SOLTU GLYCINE DEHYDROGENASE [DECARBOXYLATING], MI...   247  2e-64
pir||D83339 glycine cleavage system protein P2 PA2445 [imported]...   237  2e-61
gb|AAD56281.1|AF137264_1 (AF137264) glycine decarboxylase p prot...   237  2e-61
sp|P23378|GCSP_HUMAN GLYCINE DEHYDROGENASE [DECARBOXYLATING], MI...   236  4e-61
pir||T16734 hypothetical protein R12C12.1 - Caenorhabditis elega...   236  4e-61
gi|4504013 glycine dehydrogenase (decarboxylating; glycine decar...   235  6e-61
pir||T05309 probable glycine dehydrogenase (decarboxylating) (EC...   235  6e-61
sp|O49850|GCSP_FLAAN GLYCINE DEHYDROGENASE [DECARBOXYLATING], MI...   235  8e-61
sp|O49852|GCSP_FLATR GLYCINE DEHYDROGENASE [DECARBOXYLATING], MI...   235  1e-60
sp|Q09785|GCSP_SCHPO PUTATIVE GLYCINE DEHYDROGENASE [DECARBOXYLA...   234  1e-60
sp|P49362|GCSB_FLAPR GLYCINE DEHYDROGENASE [DECARBOXYLATING] B, ...   232  6e-60
pir||T02615 probable glycine dehydrogenase (decarboxylating) (EC...   232  6e-60
sp|P26969|GCSP_PEA GLYCINE DEHYDROGENASE [DECARBOXYLATING], MITO...   231  9e-60
pir||S40216 P protein - Flaveria pringlei >gi|438003|emb|CAA8107...   231  1e-59
sp|P49361|GCSA_FLAPR GLYCINE DEHYDROGENASE [DECARBOXYLATING] A, ...   231  1e-59
gi|6323843 Glycine decarboxylase complex (P-subunit), glycine sy...   228  8e-59
pir||T44754 probable glycine dehydrogenase (decarboxylating) (EC...   226  4e-58
pir||E75352 glycine cleavage system P protein - Deinococcus radi...   225  7e-58
pir||A39521 glycine dehydrogenase (decarboxylating) (EC 1.4.4.2)...   224  1e-57
sp|P15505|GCSP_CHICK GLYCINE DEHYDROGENASE [DECARBOXYLATING], MI...   224  1e-57
pir||C82687 glycine decarboxylase XF1385 [imported] - Xylella fa...   224  2e-57
pir||S70896 aminomethyltransferase (EC 2.1.2.10) - yeast (Saccha...   223  4e-57
sp|Q50601|GCSP_MYCTU PROBABLE GLYCINE DEHYDROGENASE [DECARBOXYLA...   222  8e-57
gb|AAF54512.1| (AE003686) CG3999 gene product [Drosophila melano...   219  4e-56
pir||T46636 glycine dehydrogenase (decarboxylating) (EC 1.4.4.2)...   217  2e-55
gb|AAA63798.1| (U11693) victorin binding protein [Avena sativa]       215  1e-54
pir||S76257 hypothetical protein - Synechocystis sp. (strain PCC...   213  3e-54
sp|P33195|GCSP_ECOLI GLYCINE DEHYDROGENASE [DECARBOXYLATING] (GL...   212  7e-54
gb|AAA69071.1| (U28377) ORF_f957 [Escherichia coli]                   212  7e-54
pir||E82994 glycine cleavage system protein P1 PA5213 [imported]...   209  5e-53
pir||D81821 glycine dehydrogenase (decarboxylating) (EC 1.4.4.2)...   203  5e-51
emb|CAA72254.1| (Y11467) putative glycine dehydrogenase (decarbo...   197  2e-49
dbj|BAB06533.1| (AP001516) glycine dehydrogenase subunit 2 [Baci...   115  1e-24
sp|P54377|GCS2_BACSU PROBABLE GLYCINE DEHYDROGENASE [DECARBOXYLA...   112  7e-24
pir||H72403 glycine dehydrogenase (decarboxylating) subunit 2 - ...   108  1e-22
pir||D75030 probable glycine dehydrogenase (decarboxylating) (EC...   102  8e-21
pir||B71216 probable glycine dehydrogenase subunit 2 - Pyrococcu...   100  3e-20
emb|CAC12478.1| (AL445067) glycine dehydrogenase (decarboxylatin...    97  4e-19
gb|AAK41199.1| Glycine dehydrogenase subunit 2 [Sulfolobus solfa...    90  6e-17
gb|AAB97081.1| (AF042072) glycine decarboxylase P subunit [Coffe...    89  1e-16
gb|AAB99844.1| (AF043097) glycine decarboxylase multi-enzyme com...    89  1e-16
gb|AAB99845.1| (AF043098) glycine decarboxylase multi-enzyme com...    89  1e-16
pir||H70463 glycine dehydrogenase (decarboxylating) - Aquifex ae...    88  2e-16
pir||D72518 probable glycine dehydrogenase subunit 2 APE2121 - A...    85  2e-15

>pir||E75030 probable glycine dehydrogenase (decarboxylating) (EC 1.4.4.2) chain
           1 PAB1171 - Pyrococcus abyssi (strain Orsay)
           >gi|5459197|emb|CAB50683.1| (AJ248288) GLYCINE
           DEHYDROGENASE (DECARBOXYLATING) SUBUNIT 1 (EC 1.4.4.2)
           (GLYCINE DECARBOXYLASE) (GLYCINE CLEAVAGE SYSTEM
           P-PROTEIN). [Pyrococcus abyssi]
           Length = 449
           
 Score =  901 bits (2304), Expect = 0.0
 Identities = 449/449 (100%), Positives = 449/449 (100%)

Query: 1   MAKHYIPNSAHKEEMLKEIGLSSIDELFADIPGKFIRDELNLPEGKSEYEVFLEMNEILG 60
           MAKHYIPNSAHKEEMLKEIGLSSIDELFADIPGKFIRDELNLPEGKSEYEVFLEMNEILG
Sbjct: 1   MAKHYIPNSAHKEEMLKEIGLSSIDELFADIPGKFIRDELNLPEGKSEYEVFLEMNEILG 60

Query: 61  KNKTVLEMPTFLGAGTYFHYIPAHVKYLIERSEFLTAYTPYQPEISQGMLQALFEYQSLI 120
           KNKTVLEMPTFLGAGTYFHYIPAHVKYLIERSEFLTAYTPYQPEISQGMLQALFEYQSLI
Sbjct: 61  KNKTVLEMPTFLGAGTYFHYIPAHVKYLIERSEFLTAYTPYQPEISQGMLQALFEYQSLI 120

Query: 121 AELVGLPVVNASMYDWGTAMAEAALMTVRLHRGKRKKFIVPRHTHPERLQVLETYAKGPG 180
           AELVGLPVVNASMYDWGTAMAEAALMTVRLHRGKRKKFIVPRHTHPERLQVLETYAKGPG
Sbjct: 121 AELVGLPVVNASMYDWGTAMAEAALMTVRLHRGKRKKFIVPRHTHPERLQVLETYAKGPG 180

Query: 181 VEIETVKWNERGQVDIEDLKEKVKDAAGVYVEIPNFFGLLEEEVREIGEIAHEAGAYFVV 240
           VEIETVKWNERGQVDIEDLKEKVKDAAGVYVEIPNFFGLLEEEVREIGEIAHEAGAYFVV
Sbjct: 181 VEIETVKWNERGQVDIEDLKEKVKDAAGVYVEIPNFFGLLEEEVREIGEIAHEAGAYFVV 240

Query: 241 GVDPTILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPGRLIG 300
           GVDPTILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPGRLIG
Sbjct: 241 GVDPTILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPGRLIG 300

Query: 301 MTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRGIRELGEV 360
           MTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRGIRELGEV
Sbjct: 301 MTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRGIRELGEV 360

Query: 361 ILKNTAYLKKRLSEVAEIPFDGVNFKDVLVRFEKPYKEIHEELLKRNIHGGYYVGKHFPE 420
           ILKNTAYLKKRLSEVAEIPFDGVNFKDVLVRFEKPYKEIHEELLKRNIHGGYYVGKHFPE
Sbjct: 361 ILKNTAYLKKRLSEVAEIPFDGVNFKDVLVRFEKPYKEIHEELLKRNIHGGYYVGKHFPE 420

Query: 421 LGESALFAATETTRKEWVDALISALREVI 449
           LGESALFAATETTRKEWVDALISALREVI
Sbjct: 421 LGESALFAATETTRKEWVDALISALREVI 449


>pir||C71216 probable glycine dehydrogenase subunit 1 - Pyrococcus horikoshii
           >gi|3258439|dbj|BAA31122.1| (AP000007) 449aa long
           hypothetical glycine dehydrogenase subunit 1 [Pyrococcus
           horikoshii]
           Length = 449
           
 Score =  857 bits (2189), Expect = 0.0
 Identities = 418/449 (93%), Positives = 439/449 (97%)

Query: 1   MAKHYIPNSAHKEEMLKEIGLSSIDELFADIPGKFIRDELNLPEGKSEYEVFLEMNEILG 60
           M  HYIPNSAHKEEMLKEIGLSSI+ELFADIP KFI++ELNLPEGKSEYEVFLEMNEIL 
Sbjct: 1   MGNHYIPNSAHKEEMLKEIGLSSIEELFADIPEKFIKEELNLPEGKSEYEVFLEMNEILE 60

Query: 61  KNKTVLEMPTFLGAGTYFHYIPAHVKYLIERSEFLTAYTPYQPEISQGMLQALFEYQSLI 120
           KNKTVLEMPTFLGAGTYFHYIPAHVK+LIERSEFLT+YTPYQPEISQGMLQALFEYQSLI
Sbjct: 61  KNKTVLEMPTFLGAGTYFHYIPAHVKHLIERSEFLTSYTPYQPEISQGMLQALFEYQSLI 120

Query: 121 AELVGLPVVNASMYDWGTAMAEAALMTVRLHRGKRKKFIVPRHTHPERLQVLETYAKGPG 180
           AELVGLPVVN+SMYDWGTAMAEAALMTVRLH+GKRKKF+VP+HTHPERLQVL TY +GP 
Sbjct: 121 AELVGLPVVNSSMYDWGTAMAEAALMTVRLHKGKRKKFVVPKHTHPERLQVLRTYTRGPE 180

Query: 181 VEIETVKWNERGQVDIEDLKEKVKDAAGVYVEIPNFFGLLEEEVREIGEIAHEAGAYFVV 240
           VEI TV WNERGQVD+EDLKEKVKDAAGVY+EIPNFFGLLEEE+RE+GEIAHEAGAYFVV
Sbjct: 181 VEIVTVNWNERGQVDVEDLKEKVKDAAGVYIEIPNFFGLLEEEIREVGEIAHEAGAYFVV 240

Query: 241 GVDPTILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPGRLIG 300
           GVDPTILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAV+NDMKLIRQMPGR+IG
Sbjct: 241 GVDPTILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVKNDMKLIRQMPGRIIG 300

Query: 301 MTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRGIRELGEV 360
           MTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGP+GIRELGEV
Sbjct: 301 MTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPKGIRELGEV 360

Query: 361 ILKNTAYLKKRLSEVAEIPFDGVNFKDVLVRFEKPYKEIHEELLKRNIHGGYYVGKHFPE 420
           ILKNTAYLKKRLSEVAEIPFDGVNFKDVLVRF+KPY+EIHEELLKRNIHGGYYVG HFPE
Sbjct: 361 ILKNTAYLKKRLSEVAEIPFDGVNFKDVLVRFDKPYREIHEELLKRNIHGGYYVGSHFPE 420

Query: 421 LGESALFAATETTRKEWVDALISALREVI 449
           LGE+ALFAATETTRKEWVDALISAL+EVI
Sbjct: 421 LGEAALFAATETTRKEWVDALISALKEVI 449


>gb|AAK41200.1| Glycine dehydrogenase subunit 1 [Sulfolobus solfataricus]
           Length = 455
           
 Score =  399 bits (1013), Expect = e-110
 Identities = 217/458 (47%), Positives = 309/458 (67%), Gaps = 18/458 (3%)

Query: 1   MAKH-YIPNSAHKEEMLKEIGLSSIDELFADIPGKF-IRDELNLPEGK--SEYEVFLEMN 56
           M KH ++PN    +EMLKEIG++S+D+LF DIP +  I   L + + K  SEYE+  E+ 
Sbjct: 1   MYKHPWLPNLDLTDEMLKEIGVNSLDDLFNDIPAEIKINRLLKVAKDKPLSEYEIEKEIY 60

Query: 57  EILGKNKTVLEMPTFLGAGTYFHYIPAHVKYLIERSEFLTAYTPYQPEISQGMLQALFEY 116
           E + KN   LE P F+GAG   HYIP  VK++I RSEF T+YTPYQPEISQG+LQALFEY
Sbjct: 61  EKVKKN-VELEAPPFIGAGICPHYIPNAVKFIIGRSEFYTSYTPYQPEISQGILQALFEY 119

Query: 117 QSLIAELVGLPVVNASMYDWGTAMAEAALMTVRLHRGKRKKFIVPRHTHPERLQVLETYA 176
           QSL+AEL+ + VVNASMYDWG+A+AEA LM  R++   +K  +VP + +P   +V+ T+ 
Sbjct: 120 QSLMAELLEMDVVNASMYDWGSALAEAVLMANRING--KKTVLVPENANPFHKEVMRTWI 177

Query: 177 KGPGVEIETVKWNER-GQVDIEDLKEKVK--DAAGVYVEIPNFFGLLEEEVREIGEIAHE 233
           +G G++IE VK+++  G+VDIEDL++K    D + +YV+ PNFFG+ E  +  I ++A  
Sbjct: 178 QGKGIKIEEVKYDKNSGEVDIEDLEKKSSSNDVSAIYVQQPNFFGIFESNIEHIIDVAKH 237

Query: 234 AGAYFVVGVDPTILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQ 293
             A  ++GV+P  LG+++ PG   ADIVVG+    G P+NFGGP  GIFAVR DM L+RQ
Sbjct: 238 KKALSIIGVNPLSLGLIKPPGSYEADIVVGDGQELGLPLNFGGPLMGIFAVRWDMGLVRQ 297

Query: 294 MPGRLIGMTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRG 353
           MPGR++G+T+D      F + LQTREQ I+R KATSNI +NEAL+A+A A++++ LG  G
Sbjct: 298 MPGRIVGITRDVNNNMGFTLILQTREQFIKREKATSNITTNEALLALANAVYLSLLGKEG 357

Query: 354 IRELGEVILKNTAYLKKRLSEVAEI--PFDGVNFKDVLVRFEKPYKEIHEELLKRNIHGG 411
           IREL E I   + Y  KRL+E+  +  PF    F++ +++F   Y  I+++L +R + GG
Sbjct: 358 IRELAEEIYFRSHYAAKRLTEIDNVIMPFTSDFFEEFVIKFPIEYNIINDKLKERKLQGG 417

Query: 412 YYVGKHFPELGESALFAATETTRKEWVDALISALREVI 449
             +  H      ++LF  TE   K+ +D L+S ++E I
Sbjct: 418 LKLSIH------TSLFCVTEVHDKKSIDLLVSTIQEAI 449


>pir||G72518 probable glycine dehydrogenase subunit 1 APE2124 - Aeropyrum pernix
           (strain K1) >gi|5105823|dbj|BAA81135.1| (AP000063) 471aa
           long hypothetical glycine dehydrogenase subunit 1
           [Aeropyrum pernix]
           Length = 471
           
 Score =  383 bits (974), Expect = e-105
 Identities = 216/462 (46%), Positives = 298/462 (63%), Gaps = 20/462 (4%)

Query: 5   YIPNSAHK---EEMLKEIGLSSIDELFADIPGKFIR-----DELNLPEGK--SEYEVFLE 54
           +IPNS HK   +EML+ IG+SS+D+L+ DIP   +      D L + EG+  SE EV   
Sbjct: 11  WIPNS-HKAILDEMLEAIGVSSVDDLYRDIPPTILLSPEEWDSLPIGEGRPLSEAEVLAR 69

Query: 55  MNEILGKNKTVLEMPTFLGAGTYFHYIPAHVKYLIERSEFLTAYTPYQPEISQGMLQALF 114
           +N+IL +NK   + P F+G G +  Y+P+ VK LI R EFLTAYTPYQ EISQG++QALF
Sbjct: 70  INDILSRNKYFTDPPPFVGGGVWPRYVPSVVKALITRGEFLTAYTPYQAEISQGLMQALF 129

Query: 115 EYQSLIAELVGLPVVNASMYDWGTAMAEAALMTVRLHRGKRKKFIVPRHTHPERLQVLET 174
           EYQSL+AEL+ + VVNAS+YDW +A+ EA LM  R+ R  R + +VP   +P  L+   T
Sbjct: 130 EYQSLVAELLEMEVVNASLYDWSSAVGEAMLMARRVTR--RNRVLVPETMNPLHLETATT 187

Query: 175 YAKGPGVEIETVKWN-ERGQVDIEDLKEKVK--DAAGVYVEIPNFF-GLLEEEVREIGEI 230
           YA G G+ +E V+ + E G +D+EDL+ ++   D A +Y+E P+ + G+++E V   GE 
Sbjct: 188 YAYGGGIRVEKVRVDRETGFIDLEDLESRLSQGDTAALYMEYPSSYTGVIDENVEAAGEA 247

Query: 231 AHEAGAYFVVGVDPTILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVRNDMKL 290
            H+AG  F++GV+P  + I++ PG LGADI VG+    G  +N+GGP  G+FAVR D +L
Sbjct: 248 VHKAGGLFILGVEPVSMAILKPPGRLGADIAVGDGQPLGLGLNYGGPYLGVFAVRWDGRL 307

Query: 291 IRQMPGRLIGMTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLG 350
           +RQMPGRLIGMT DAEG+RAF M LQTREQHIRRAKATSNI +NEAL+A+AAA++++ LG
Sbjct: 308 VRQMPGRLIGMTVDAEGRRAFAMILQTREQHIRRAKATSNITTNEALMAIAAAVYLSLLG 367

Query: 351 PRGIRELGEVILKNTAYLKKRLSEV--AEIP-FDGVNFKDVLVRFEKPYKEIHEELLKRN 407
           P+G+RE+ E     + Y  KRLSE+   E P  +G    D  VR           LL++ 
Sbjct: 368 PQGLREVAEASWYMSHYAAKRLSELRGVEAPLLEGEFIMDFTVRLPMDAGVARRRLLEKG 427

Query: 408 IHGGYYVGKHFPELGESALFAATETTRKEWVDALISALREVI 449
           +  G  +G          L   TE   +  VD L++ L  V+
Sbjct: 428 VLAGIPLGGFSFFSDNDMLLTVTEAHTRRHVDLLVNLLDSVL 469


>sp|P54376|GCS1_BACSU PROBABLE GLYCINE DEHYDROGENASE [DECARBOXYLATING] SUBUNIT 1 (GLYCINE
           DECARBOXYLASE) (GLYCINE CLEAVAGE SYSTEM P-PROTEIN)
           >gi|7451835|pir||A69959 glycine dehydrogenase homolog
           yqhJ - Bacillus subtilis >gi|1303891|dbj|BAA12547.1|
           (D84432) YqhJ [Bacillus subtilis]
           >gi|2634890|emb|CAB14387.1| (Z99116) similar to glycine
           dehydrogenase [Bacillus subtilis]
           Length = 448
           
 Score =  379 bits (962), Expect = e-104
 Identities = 202/449 (44%), Positives = 293/449 (64%), Gaps = 10/449 (2%)

Query: 1   MAKHYIP-NSAHKEEMLKEIGLSSIDELFADIPGKF-IRDELNLPEGKSEYEVFLEMNEI 58
           M   Y+P     K+EML  IG+SSID+LFADIP     + E  + + KSE E+  E+ ++
Sbjct: 1   MKHRYLPATEKDKQEMLATIGVSSIDDLFADIPENVKYKKEHQIKKAKSETELTRELTKL 60

Query: 59  LGKNKTVLEMPTFLGAGTYFHYIPAHVKYLIERSEFLTAYTPYQPEISQGMLQALFEYQS 118
             KN+  ++  +FLGAG Y HY P  V ++I RSEF TAYTPYQPEISQG LQA+FE+Q+
Sbjct: 61  ASKNRDTVQYASFLGAGVYDHYQPVIVDHVISRSEFYTAYTPYQPEISQGELQAIFEFQT 120

Query: 119 LIAELVGLPVVNASMYDWGTAMAEAALMTVRLHRGKRKKFIVPRHTHPERLQVLETYAKG 178
           +I EL G+ + N+SMYD GTA+AEAA++       K+KK +V +  HPE  +VL+TYAKG
Sbjct: 121 MICELTGMDIANSSMYDGGTALAEAAMLA--SGHTKKKKIVVSKTVHPESREVLKTYAKG 178

Query: 179 PGVEIETVKWNERGQVDIEDLKEKV-KDAAGVYVEIPNFFGLLEEEVREIGEIAHEAGAY 237
             +++  V   + G  D++ L++ V ++ A V V+ PNFFG + E +++I  IAH+  + 
Sbjct: 179 QYIDVVEVPAAD-GVTDLDALRQTVCENTAAVIVQYPNFFGRI-EPLKDIEPIAHQGKSM 236

Query: 238 FVVGVDPTILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPGR 297
           F+V  +P  LG++  PG+  +DIVVG+A  FG P  +GGP  G FAV    KL+R++PGR
Sbjct: 237 FIVSANPLALGLLTPPGKFQSDIVVGDAHRFGIPSAYGGPHCGFFAVTK--KLMRKVPGR 294

Query: 298 LIGMTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRGIREL 357
           L+G T+D  GKR FV+TLQ REQHIRR KATSNICSN+AL A+AA++ + +LG  G++++
Sbjct: 295 LVGQTEDENGKRGFVLTLQAREQHIRRDKATSNICSNQALNALAASVAMTALGKNGVKDI 354

Query: 358 GEVILKNTAYLKKRLSEVA-EIPFDGVNFKDVLVRFEKPYKEIHEELLKRNIHGGYYVGK 416
               L    Y K+   +    + FDG  F + +++ ++P + +++ LL + + GGY +G 
Sbjct: 355 ARQNLLKANYAKQEAKKAGLTVMFDGPMFNEFVIKLDEPVRAVNKRLLAKGMIGGYDLGL 414

Query: 417 HFPELGESALFAATETTRKEWVDALISAL 445
            +PEL    L A TE   KE +DALI  L
Sbjct: 415 TYPELDCHMLIAVTELRTKEEIDALIQEL 443


>dbj|BAB06534.1| (AP001516) glycine dehydrogenase subunit 1 [Bacillus halodurans]
           Length = 447
           
 Score =  366 bits (930), Expect = e-100
 Identities = 202/443 (45%), Positives = 283/443 (63%), Gaps = 10/443 (2%)

Query: 1   MAKHYIPNSAH-KEEMLKEIGLSSIDELFADIPGKF-IRDELNLPEGKSEYEVFLEMNEI 58
           M   Y+P +   ++EML+ IG+ SI+ELF+DIP     + +LN+P    E E+     ++
Sbjct: 1   MNHRYLPMTTDDRQEMLQAIGVDSIEELFSDIPQDIRFKGKLNIPNALKEPELIRYFQQL 60

Query: 59  LGKNKTVLEMPTFLGAGTYFHYIPAHVKYLIERSEFLTAYTPYQPEISQGMLQALFEYQS 118
             +N  + +  +FLGAG Y HYIP+ V ++I RSEF TAYTPYQPEISQG LQA+FE+Q+
Sbjct: 61  ANENVHLKDKASFLGAGVYDHYIPSIVDHVISRSEFYTAYTPYQPEISQGELQAIFEFQT 120

Query: 119 LIAELVGLPVVNASMYDWGTAMAEAALMTVRLHRGKRKKFIVPRHTHPERLQVLETYAKG 178
           +I EL G+ V N+SMYD  TA+AEAA+M+      K+KK +V +  HPE   VL T A G
Sbjct: 121 MICELTGMEVANSSMYDGPTALAEAAMMS--CGHTKKKKILVSKAVHPEARDVLMTNAYG 178

Query: 179 PGVEIETVKWNERGQVDIEDLKEKV-KDAAGVYVEIPNFFGLLEEEVREIGEIAHEAGAY 237
             +E+  +  N  G  D+E LK    ++ A V V+ PNFFG L E + EI  ++H+  A 
Sbjct: 179 QRLEVVEIDTN-NGVTDVEHLKALYDEETACVIVQHPNFFGRL-EPLAEIESVSHQGKAT 236

Query: 238 FVVGVDPTILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPGR 297
           FVV  +P  LG+++ PG  GAD+VVG+A  FG P  +GGP  G FA     KL+R++PGR
Sbjct: 237 FVVSSNPLALGLLKPPGAFGADVVVGDAQPFGIPTQYGGPHCGYFATTK--KLMRKVPGR 294

Query: 298 LIGMTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRGIREL 357
           L+G T D +G+R FV+TLQ REQHIRR KATSNICSN+AL A+AAA+ +A++G RG++E+
Sbjct: 295 LVGQTTDDQGQRGFVLTLQAREQHIRREKATSNICSNQALNALAAAVAMATIGKRGVKEM 354

Query: 358 GEVILKNTAYLKKRL-SEVAEIPFDGVNFKDVLVRFEKPYKEIHEELLKRNIHGGYYVGK 416
               ++  AY K +L +   EI  +G  F + +++   P  E+ E LL +    GY +GK
Sbjct: 355 ALQNVQKAAYAKSQLKANGVEIVAEGPCFNEFIIKLSSPLHEVEEALLAKGFIAGYDLGK 414

Query: 417 HFPELGESALFAATETTRKEWVD 439
            +PEL    L A TE   KE +D
Sbjct: 415 VYPELEGHMLVAVTEVRTKEEID 437


>pir||G72403 glycine dehydrogenase (decarboxylating) subunit 1 - Thermotoga
           maritima (strain MSB8)
           >gi|4980711|gb|AAD35305.1|AE001706_4 (AE001706) glycine
           dehydrogenase (decarboxylating) subunit 1 [Thermotoga
           maritima]
           Length = 437
           
 Score =  347 bits (882), Expect = 1e-94
 Identities = 196/445 (44%), Positives = 279/445 (62%), Gaps = 15/445 (3%)

Query: 5   YIPNSAHK-EEMLKEIGLSSIDELFADIPGKFIRDELNLPEGKSEYEVFLEMNEILGKNK 63
           YIP++      ML  IG+SSI+ELF+ IP    R  LN+PE + E+ VF ++ EI   N 
Sbjct: 5   YIPHTDEDVRAMLDFIGVSSIEELFSSIPVS-ARSSLNIPESRDEFSVFKQLKEISEMNN 63

Query: 64  TVLEMPTFLGAGTYFHYIPAHVKYLIERSEFLTAYTPYQPEISQGMLQALFEYQSLIAEL 123
           ++ +   FLGAG Y  Y+P  V  L  + +FLTAYTPYQ E+SQG LQALFEYQ+++ EL
Sbjct: 64  SLEDYAVFLGAGVYKRYVPTVVYDLAMKPDFLTAYTPYQAEVSQGTLQALFEYQTMVCEL 123

Query: 124 VGLPVVNASMYDWGTAMAEAALMTVRLHRGKRKKFIVPRHTHPERLQVLETYAKGPGVEI 183
            G+ V NASMYD  TA+AEAALM+ RL  GK +K +V R  HPE   VL TY +  G  +
Sbjct: 124 TGMEVANASMYDGATALAEAALMSFRL-TGK-EKVVVARSVHPEYRAVLRTYLEKRGFTV 181

Query: 184 ETVKWNERGQVDIEDLKEKVKDAAGVYVEIPNFFGLLEEEVREIGEIAHEAG-AYFVVGV 242
               ++E G+V +E++ E   + A + V+ PNFFG++E    ++  +   +G A  +V V
Sbjct: 182 VEAGYDETGRVLLEEVDE---ETAAIAVQYPNFFGIIE----DLDYVRSRSGNALLIVVV 234

Query: 243 DPTILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPGRLIGMT 302
           +P  L ++E PG  GADIVVGE    G PM FGG   GIFA R +   +RQMPGRLIG T
Sbjct: 235 EPVSLALLEPPGSYGADIVVGEGQSLGLPMWFGGYSLGIFATREE--YVRQMPGRLIGQT 292

Query: 303 KDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRGIRELGEVIL 362
            D  G  A+ M LQTREQHIRRA+ATSNICSN A  A+ AA++++ +GP G++E+     
Sbjct: 293 VDQAGNTAYTMILQTREQHIRRARATSNICSNHAHAALIAAVYMSVMGPDGLKEVARRSY 352

Query: 363 KNTAYLKKRLSEVA-EIPFDGVNFKDVLVRFEKPYKEIHEELLKRNIHGGYYVGKHFPEL 421
               YL++RL E+  ++ F G  F + +    + Y +   +++++ I G   + + +PEL
Sbjct: 353 NAAHYLQERLEEIGFKLCFSGEFFNEFVFNVPEDYPDRWRKMMEKKILGPLPLEEFYPEL 412

Query: 422 GESALFAATETTRKEWVDALISALR 446
           G++AL  ATE   KE ++ L+ A++
Sbjct: 413 GDTALACATEVISKEDIEKLLEAMK 437


>emb|CAC12479.1| (AL445067) glycine dehydrogenase (decarboxylating) related protein,
           subunit 1 [Thermoplasma acidophilum]
           Length = 433
           
 Score =  327 bits (829), Expect = 2e-88
 Identities = 181/438 (41%), Positives = 273/438 (62%), Gaps = 15/438 (3%)

Query: 15  MLKEIGLSSIDELFADIPGKFIRDELNLPEGKSEYEVFLEMNEILGKNKTVLEMPTFLGA 74
           ML  +G+   +ELF+DIP    +  + +  G  EY V     EI  KNKT  +M  FLG 
Sbjct: 7   MLNFLGMKDPEELFSDIPKSVRKKSIGIGGGLDEYRVIDRAMEIGRKNKT--DMINFLGN 64

Query: 75  GTYFHYIPAHVKYLIERSEFLTAYTPYQPEISQGMLQALFEYQSLIAELVGLPVVNASMY 134
           G Y   IP  V Y++ + EFL +YTPYQPEISQGMLQ++FEYQSLI++L+G+ V NASMY
Sbjct: 65  GIYDRVIPEAVNYILSKPEFLDSYTPYQPEISQGMLQSMFEYQSLISDLMGMDVTNASMY 124

Query: 135 DWGTAMAEAALMTVRLHRGKRKKFIVPRHTHPERLQVLETYAKGPGVEIETVKWNERGQV 194
           D  +A+ EAA M  R++     K +VP  ++  ++ VL  Y  G  ++I   +  E G +
Sbjct: 125 DGYSALGEAARMAYRING--HSKILVPESSYDSKISVLRNYIWGLNMKIMKYRIGEDGMI 182

Query: 195 DIEDLKEKV-KDAAGVYVEIPNFFGLLEEEVREIGEIAHEAGAYFVVGVDPTILGIVEAP 253
           D++DL  K+  D + + VE PN +G+L++ +  + +I  +A    +  VDP  LG+V+ P
Sbjct: 183 DLDDLSSKIDSDTSAIVVENPNGYGILDKNIFGVKDIKKDA--VLISYVDPISLGVVKPP 240

Query: 254 GELGADIVVGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPGRLIGMTKDAEGKRAFVM 313
           GE G+DI V E    G PMNFGGP  G+ + +  M+ IR+ PGR+IG + D+ GKRA+VM
Sbjct: 241 GEYGSDIAVAEGQQLGIPMNFGGPLLGLMSFK--MEHIRRSPGRIIGESIDSNGKRAYVM 298

Query: 314 TLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRGIRELGEVILKNTAYLKKRLS 373
           TLQTREQHIRRAKATSNICSN+AL+ +AA+ +++ +G  G+R++  + +K++  +K++LS
Sbjct: 299 TLQTREQHIRRAKATSNICSNQALLTLAASAYLSIMGSTGLRKVALLTIKHSRMIKEKLS 358

Query: 374 EVAEIP-FDGVNFKDVLVRFEKPYKEIHEELLKRNIHGGYYVGKHFPE--LGESALFAAT 430
            +   P F   +F DV+ R E   +++ E L  +NI GG  + +   +  + ++  F  T
Sbjct: 359 SIGVKPYFSTESFSDVMFRLE---RDVMEALASKNILGGLKLRQLISDTPMKDATFFTVT 415

Query: 431 ETTRKEWVDALISALREV 448
           E T    ++ L +AL  +
Sbjct: 416 EKTDAAAIEKLAAALEVI 433


>pir||F70395 glycine dehydrogenase (decarboxylating) - Aquifex aeolicus
           >gi|2983571|gb|AAC07143.1| (AE000723) glycine
           dehydrogenase (decarboxylating) [Aquifex aeolicus]
           Length = 439
           
 Score =  323 bits (818), Expect = 3e-87
 Identities = 186/446 (41%), Positives = 274/446 (60%), Gaps = 14/446 (3%)

Query: 5   YIPNSAHK-EEMLKEIGLSSIDELFADIPGKFIRDELNLPEGKSEYEVFLEMNEILGKNK 63
           YIP+S  + +E+L ++GL S+++LF+ IP +    + + PE KSE E    +  I  +  
Sbjct: 3   YIPHSEEETKEILSKLGLESLEDLFSHIPKELFAKDFSFPEPKSEEE----LRRIFERAC 58

Query: 64  TVLEMPT-FLGAGTYFHYIPAHVKYLIERSEFLTAYTPYQPEISQGMLQALFEYQSLIAE 122
              E+P  F+GAG Y   IP+ +  ++ R EFLT YTPYQ E SQG LQA+FEYQSLI E
Sbjct: 59  EDTELPLYFIGAGAYDRIIPSVIWQILSRGEFLTPYTPYQAEASQGTLQAIFEYQSLICE 118

Query: 123 LVGLPVVNASMYDWGTAMAEAALMTVRLHRGKRKKFIVPRHTHPERLQVLETYAKGPGVE 182
           L G+ V NASMYD  +A+AEA LM  R  +GK    ++ +  +P   + ++TY +G   +
Sbjct: 119 LTGMDVANASMYDGASALAEAVLM-ARAIKGKGDTVVLSKALNPLYRRTVKTYLRGYEDK 177

Query: 183 IETVKWNERGQVDIEDLKEKVKDAA--GVYVEIPNFFGLLEEEVREIGEIAHEAGAYFVV 240
           I  V + E G  D+ +L+E +K++    + V+ PNFFG + E ++EIGE+  +    FVV
Sbjct: 178 IVEVPYTEEGTTDLNNLEEVLKESEVHALAVQYPNFFGFV-EPLKEIGELCKKYEVPFVV 236

Query: 241 GVDPTILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPGRLIG 300
            VDP  L I++ P E GADIVVGE    G P++FGGP  G FA + +   +R+MPGRL+G
Sbjct: 237 FVDPIALSILKPPAEFGADIVVGEGQQMGIPLSFGGPYVGFFATKKEH--VRKMPGRLVG 294

Query: 301 MTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRGIRELGEV 360
           M +D EGKRAF + LQTREQHIRR +ATSNIC+N+ L+A+A  +++  LG  G++++   
Sbjct: 295 MGEDIEGKRAFTLVLQTREQHIRRERATSNICTNQNLMALANLLYMVLLGKEGMKKVAVQ 354

Query: 361 ILKNTAYLKKRLSEVA-EIPFDGVNFKDVLVRFEKPYKEIHEELLKRNIHGGYYVGKHFP 419
            L    Y KK L +   E  F G +  +  +R E   K I+ +LLK  I  G  + + + 
Sbjct: 355 SLSKALYFKKELMKKGFEEVFTGKHLWEFPLRHES-LKAIYRKLLKEKIVLGLPLDRFYE 413

Query: 420 ELGESALFAATETTRKEWVDALISAL 445
           +L  + L A TE   KE +D++++ L
Sbjct: 414 DLKNTTLIAVTEKRTKEEIDSVLALL 439


>gb|AAG19868.1| (AE005071) glycine dehydrogenase subunit 1; GcvP1 [Halobacterium
           sp. NRC-1]
           Length = 441
           
 Score =  284 bits (719), Expect = 1e-75
 Identities = 174/447 (38%), Positives = 251/447 (55%), Gaps = 21/447 (4%)

Query: 7   PNSAHKEEMLKEIGLSSIDELFADIPGKFIRDELNLPEGKSEYEVFLEMNEILGKNKTVL 66
           P+ A  + ML  +G+  +DELF DIP +   D     + KSE      +   L  N  + 
Sbjct: 9   PSEADTDAMLDAVGVDRVDELF-DIPPEVSFDGEFGIDAKSEQAALRGVRRRLSDNDDLT 67

Query: 67  EMPTFLGAGTYFHYIPAHVKYLIERSEFLTAYTPYQPEISQGMLQALFEYQSLIAELVGL 126
           E   FLG G Y HY+P+ V  + +RSEF+T+YT YQPEI+QG LQ LFEYQSL+ EL GL
Sbjct: 68  E---FLGRGHYEHYVPSLVDSVSQRSEFITSYTQYQPEITQGFLQVLFEYQSLLVELTGL 124

Query: 127 PVVNASMYDWGTAMAEAALMTVRLHRGKRKKFIVPRHTHPERLQVLETYAKGPGVEIETV 186
            V N SMYD  TA+AEAAL+  R+      + +VP       + VL  Y  G  V +E  
Sbjct: 125 GVANCSMYDAATALAEAALLAKRVRAADGNRVLVPGFVRDSHVDVLRNYTSGSDVVVERY 184

Query: 187 KWNERGQVDIEDLKEKV-KDAAGVYVEIPNFFGLLEEEVREIGEIAHEAGAYFVVGVDPT 245
              + G VD++ L+  +  D   VY E P   G +EE++  +G++A    A F +G DP 
Sbjct: 185 A-TDAGNVDLDALEAAMDADVVMVYAENPTTCGTVEEQLCAVGDLADSHDALFCLGSDPV 243

Query: 246 ILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPGRLIGMTKDA 305
            + I++ P ++GAD+VVG+AS  G P ++ G   G+FA R +   +RQ+PGRL+G ++D 
Sbjct: 244 AMSILQRPVDVGADVVVGDASVLGMPTSY-GTGLGVFATRKE--FLRQVPGRLVGASEDD 300

Query: 306 EGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRGIRELGEVILKNT 365
            G RAF +TLQTREQHIR+ +ATSNIC+N+A VA+ AAIH A LG  G+ +L E +++  
Sbjct: 301 AGTRAFTLTLQTREQHIRKERATSNICTNQAWVALRAAIHAAWLGADGLVDLAERMVELP 360

Query: 366 AYLKKRLSEV----AEIPFDGVNFKDVLVRFEKPYKEIHEELLKRNIHGGYYVGKHFPEL 421
             L  RL +V    A +  D  + ++   R E+P   +    L+    G + V  H    
Sbjct: 361 RDLAARLDDVSGVTAPVHDDRHHIREFQARTEQPAPAV-ASALEAEGFGVHAVDDH---- 415

Query: 422 GESALFAATETTRKEWVDALISALREV 448
               +        +   DA ++A+REV
Sbjct: 416 ---TIQVCVTDANEHATDAFVAAVREV 439


>sp|O49954|GCSP_SOLTU GLYCINE DEHYDROGENASE [DECARBOXYLATING], MITOCHONDRIAL PRECURSOR
           (GLYCINE DECARBOXYLASE) (GLYCINE CLEAVAGE SYSTEM
           P-PROTEIN) >gi|7489225|pir||T07826
           aminomethyltransferase (EC 2.1.2.10) precursor - potato
           >gi|2894362|emb|CAB16918.1| (Z99770) P-Protein precursor
           [Solanum tuberosum]
           Length = 1035
           
 Score =  247 bits (624), Expect = 2e-64
 Identities = 156/389 (40%), Positives = 222/389 (56%), Gaps = 33/389 (8%)

Query: 8   NSAHKEEMLKEI---GLSSIDELF-ADIPGKFIRDELNLPE---GKSEYEVFLEMNEILG 60
           NSA  EE  K     G  S+D L  A +P     + + LP+   G +E ++   M  +  
Sbjct: 81  NSATPEEQTKMAEFCGFQSLDALIDATVPQSIRSESMKLPKFDSGLTESQMIEHMQNLAS 140

Query: 61  KNKTVLEMPTFLGAGTYFHYIPAHV-KYLIERSEFLTAYTPYQPEISQGMLQALFEYQSL 119
           KNK      +++G G Y  Y+P  + + L+E   + T YTPYQ EISQG L++L  YQ++
Sbjct: 141 KNKV---FKSYIGMGYYNTYVPPVILRNLLENPAWYTQYTPYQAEISQGRLESLLNYQTM 197

Query: 120 IAELVGLPVVNASMYDWGTAMAEAALMTVRLHRGKRKKFIVPRHTHPERLQVLETYAKGP 179
           I +L GLP+ NAS+ D GTA AEA  M   + +GK+K F++  + HP+ + + +T A G 
Sbjct: 198 ITDLTGLPMSNASLLDEGTAAAEAMAMCNNILKGKKKTFLIASNCHPQTIDICKTRADGF 257

Query: 180 GVEIETVKWNERGQVDIEDLKEKVKDAAGVYVEIPNFFGLLEEEVREIGEI---AHEAGA 236
            +++ TV        D++D+  K  D  GV V+ P      E E+ + GE    AH  G 
Sbjct: 258 DLKVVTV--------DLKDIDYKSGDVCGVLVQYPG----TEGEILDYGEFIKNAHAHGV 305

Query: 237 YFVVGVDPTILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPG 296
             V+  D   L +++ PGELGADIVVG A  FG PM +GGP A   A   + K  R MPG
Sbjct: 306 KVVMASDLLALTMLKPPGELGADIVVGSAQRFGVPMGYGGPHAAFLATSQEYK--RMMPG 363

Query: 297 RLIGMTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRGIRE 356
           R+IG++ D+ GK A  M +QTREQHIRR KATSNIC+ +AL+A  AA++    GP G++ 
Sbjct: 364 RIIGLSVDSTGKPALRMAMQTREQHIRRDKATSNICTAQALLANMAAMYAVYHGPEGLKT 423

Query: 357 LGEVI--LKNT--AYLKK-RLSEVAEIPF 380
           +G+ +  L  T  A LKK    EV ++PF
Sbjct: 424 IGQRVHGLAGTFSAGLKKLGTVEVQDLPF 452


>pir||D83339 glycine cleavage system protein P2 PA2445 [imported] - Pseudomonas
           aeruginosa (strain PAO1)
           >gi|9948493|gb|AAG05833.1|AE004672_1 (AE004672) glycine
           cleavage system protein P2 [Pseudomonas aeruginosa]
           Length = 959
           
 Score =  237 bits (599), Expect = 2e-61
 Identities = 146/393 (37%), Positives = 212/393 (53%), Gaps = 20/393 (5%)

Query: 1   MAKHYIPNSAHKEEMLKEIGLSSIDELFADIPGKFIRDE--LNLPEGKSEYEVFLEMNEI 58
           +A+H  P +A  + ML+ +G  S+D L  ++    I+    L+LP G  E E    +  I
Sbjct: 19  IARHIGPRAADTQAMLQRLGYDSLDTLIGNVIPDSIKGSSVLDLPAGMGEAEALASLKAI 78

Query: 59  LGKNKTVLEMPTFLGAGTYFHYIPAHV-KYLIERSEFLTAYTPYQPEISQGMLQALFEYQ 117
             +N+    + +F+G G Y  + PA + + L+E   + TAYTPYQPEISQG L+AL  +Q
Sbjct: 79  AARNRA---LRSFIGQGYYNCHTPAPILRNLLENPAWYTAYTPYQPEISQGRLEALLNFQ 135

Query: 118 SLIAELVGLPVVNASMYDWGTAMAEAALMTVRLHRGKRKK-FIVPRHTHPERLQVLETYA 176
           +L+++L GLP+ NASM D  TA AEA     RL + +  + F   RH HP+ L VL T A
Sbjct: 136 TLVSDLSGLPIANASMLDEATAAAEAMTFCKRLSKNRTSQAFFASRHCHPQTLDVLRTRA 195

Query: 177 KGPGVEIETVKWNERGQVDIEDLKEKVKDAAGVYVEIPNFFGLLEEEVREIGEIAHEAGA 236
           +  G+E+          V  E   E      G  ++ P   G +  + RE+    H   A
Sbjct: 196 EPLGIEV---------VVGDESTIEDFSAYFGALLQYPTCDGEI-VDYRELVSRFHAVDA 245

Query: 237 YFVVGVDPTILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPG 296
              V  D   L ++  PGE GAD+ +G A  FG P+ FGGP A  FA R+  K  R MPG
Sbjct: 246 LVAVAADLLALTLLTPPGEFGADVAIGSAQRFGVPLGFGGPHAAYFATRDAFK--RDMPG 303

Query: 297 RLIGMTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRGIRE 356
           RL+G++ D  GK A+ + +QTREQHIRR KATSNIC+ + L+A  A++     GP+G+  
Sbjct: 304 RLVGVSIDRHGKPAYRLAMQTREQHIRREKATSNICTAQVLLANIASMFAVYHGPQGLLR 363

Query: 357 LGEVILKNTAYLKKRLSEVAEIPFDGVNFKDVL 389
           +     + TA L   L  +  +  +  +F D L
Sbjct: 364 IARRTHRLTAILAAGLERLG-VAVEQKHFFDTL 395


 Score = 71.8 bits (173), Expect = 1e-11
 Identities = 87/368 (23%), Positives = 148/368 (39%), Gaps = 54/368 (14%)

Query: 100 PYQP-EISQGMLQALFEYQSLIAELVGLPVVNASMYDWGTAMAEAALMTVRLHR-----G 153
           P+ P E S+G  Q   E ++++    G   V+    + G+    A L+ +R +       
Sbjct: 538 PFAPAEQSEGYRQLTDELEAMLCSATGYDAVSLQP-NAGSQGEYAGLLAIRAYHQSRGDS 596

Query: 154 KRKKFIVPRHTHPERLQVLETYAKGPGVEIETVKWNERGQVDIEDLKEKVKD----AAGV 209
           +R   ++P   H          A   G+ +  V  + RG VD+EDL+ K  +     A +
Sbjct: 597 QRDICLIPSSAHGTN----PATASMVGMRVVVVACDARGNVDVEDLRNKASEHKERLAAL 652

Query: 210 YVEIPNFFGLLEEEVREIGEIAHEAGA-YFVVGVDPTILGIVEAPGELGADIV-VGEASY 267
            +  P+  G+ EE +REI  I H+ G   ++ G +   +  + APG+ G D+  +     
Sbjct: 653 MITYPSTHGVFEEAIREICAIVHDCGGQVYIDGANMNAMVGLCAPGKFGGDVSHLNLHKT 712

Query: 268 FGNPMNFGGPRAGIFAVRNDMKLIRQMPGRLIGMTKDAEGKRAFVMTLQTREQHIRRAKA 327
           F  P   GGP  G   VR    L   +PG   G  K+                      A
Sbjct: 713 FCIPHGGGGPGVGPIGVR--AHLAPFLPGHARGERKEG---------------------A 749

Query: 328 TSNICSNEALVAVAAAIHIASLGPRGIRELGEVILKNTAYLKKRLSEVAEIPFDGVNFKD 387
            S      A +     ++I  +G  G++   E+ + N  Y+  RL E   + + G N   
Sbjct: 750 VSAAPYGSASILPITWMYIRMMGGEGLKRASEMAILNANYIAHRLEEHYPVLYAGGN--- 806

Query: 388 VLVRFE-----KPYKEIH----EELLKRNIHGGYYV-GKHFPELGESALFAATETTRKEW 437
            LV  E     +P K+      +++ KR +  G++     FP  G + +   TE+  K  
Sbjct: 807 GLVAHECILDLRPLKDSSGISVDDVAKRLMDFGFHAPTMSFPVAG-TLMIEPTESESKAE 865

Query: 438 VDALISAL 445
           +D    A+
Sbjct: 866 LDRFCDAM 873


>gb|AAD56281.1|AF137264_1 (AF137264) glycine decarboxylase p protein [Anas platyrhynchos]
           Length = 1024
           
 Score =  237 bits (599), Expect = 2e-61
 Identities = 148/414 (35%), Positives = 224/414 (53%), Gaps = 19/414 (4%)

Query: 3   KHYIPNSAHKEEMLKEIGLSSIDELFAD-IPGKF-IRDELNLPEGKSEYEVFLEMNEILG 60
           +H  P    K EML+ +G+ S++EL    IPG   +R  L + +   E E+   +  I  
Sbjct: 70  RHIGPREGEKREMLRALGVQSVEELMDKAIPGSIRLRRPLRMEDPVGENEILETLYNIAS 129

Query: 61  KNKTVLEMPTFLGAGTYFHYIPAHV-KYLIERSEFLTAYTPYQPEISQGMLQALFEYQSL 119
           KNK      +++G G Y   +P  + + L+E + ++T YTPYQPE+SQG L++L  YQ++
Sbjct: 130 KNKI---WRSYIGMGYYNCSVPQPIARNLLENAGWVTQYTPYQPEVSQGRLESLLNYQTM 186

Query: 120 IAELVGLPVVNASMYDWGTAMAEAALMTVRLHRGKRKKFIVPRHTHPERLQVLETYAKGP 179
           + ++ G+ V NAS+ D GTA AEA  +  R    KR+KF V    HP+ + V++T A   
Sbjct: 187 VCDITGMDVANASLLDEGTAAAEAMQLCHR--HNKRRKFYVDSRCHPQTIAVVQTRANYT 244

Query: 180 GVEIETVKWNERGQVDIEDLKEKVKDAAGVYVEIPNFFGLLEEEVREIGEIAHEAGAYFV 239
           GV  E    +E        +    KD +GV  + P+  G +E+   E+ E AH+ G    
Sbjct: 245 GVITELKLPHE--------MDFSGKDVSGVLFQYPDTEGKVED-FSELVERAHQNGTLAC 295

Query: 240 VGVDPTILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPGRLI 299
              D   L I++ PGE G D+V+G +  FG P+ +GGP A  FAV+ +  L+R MPGR++
Sbjct: 296 CATDLLALCILKPPGEFGVDVVLGSSQRFGVPLCYGGPHAAFFAVKEN--LVRMMPGRMV 353

Query: 300 GMTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRGIRELGE 359
           G+T+DA GK  + + LQTREQHIRR KATSNIC+ +AL+A  AA+     G  G+R++  
Sbjct: 354 GVTRDANGKEVYRLALQTREQHIRRDKATSNICTAQALLANMAAMFGVYHGSDGLRDIAR 413

Query: 360 VILKNTAYLKKRLSEVAEIPFDGVNFKDVLVRFEKPYKEIHEELLKRNIHGGYY 413
            +   T  L + L          + F  + V      KE+ +    R I+   Y
Sbjct: 414 RVHNATLILAEGLRRAGHKLHHDLFFDTLTVTCGCSVKEVLDRAALRKINFRIY 467


>sp|P23378|GCSP_HUMAN GLYCINE DEHYDROGENASE [DECARBOXYLATING], MITOCHONDRIAL PRECURSOR
           (GLYCINE DECARBOXYLASE) (GLYCINE CLEAVAGE SYSTEM
           P-PROTEIN) >gi|87570|pir||JN0124 glycine dehydrogenase
           (decarboxylating) (EC 1.4.4.2) - human
           >gi|190287|gb|AAA36478.1| (M63635) glycine decarboxylase
           [Homo sapiens]
           Length = 1020
           
 Score =  236 bits (596), Expect = 4e-61
 Identities = 148/403 (36%), Positives = 222/403 (54%), Gaps = 30/403 (7%)

Query: 3   KHYIPNSAHKEEMLKEIGLSSIDELFAD-IPGKF-IRDELNLPEGKSEYEVFLEMNEILG 60
           +H  P    + EML+ +GL+SIDEL    +P    ++  L + +   E E+   ++ I  
Sbjct: 66  RHIGPGDKDQREMLQTLGLASIDELIEKTVPANIRLKRPLKMEDPVCENEILATLHAISS 125

Query: 61  KNKTVLEMPTFLGAGTYFHYIPAHV-KYLIERSEFLTAYTPYQPEISQGMLQALFEYQSL 119
           KN+      +++G G Y   +P  + + L+E S ++T YTPYQPE+SQG L++L  YQ++
Sbjct: 126 KNQI---WRSYIGMGYYNCSVPQTILRNLLENSGWITQYTPYQPEVSQGRLESLLNYQTM 182

Query: 120 IAELVGLPVVNASMYDWGTAMAEAALMTVRLHRGKRKKFIVPRHTHPERLQVLETYAKGP 179
           + ++ GL + NAS+ D GTA AEA  +  R    KR+KF+V    HP+ + V++T AK  
Sbjct: 183 VCDITGLDMANASLLDEGTAAAEALQLCYR--HNKRRKFLVDPRCHPQTIAVVQTRAKYT 240

Query: 180 GVEIETVKWNERGQVDIEDLKEKVKDAAGVYVEIPNFFGLLEEEVREIGEIAHEAGAYFV 239
           GV  E     E        +    KD +GV  + P+  G +E+   E+ E AH++G+   
Sbjct: 241 GVLTELKLPCE--------MDFSGKDVSGVLFQYPDTEGKVED-FTELVERAHQSGSLAC 291

Query: 240 VGVDPTILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPGRLI 299
              D   L I+  PGE G DI +G +  FG P+ +GGP A  FAVR    L+R MPGR++
Sbjct: 292 CATDLLALCILRPPGEFGVDIALGSSQRFGVPLGYGGPHAAFFAVRES--LVRMMPGRMV 349

Query: 300 GMTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRGIRELGE 359
           G+T+DA GK  + + LQTREQHIRR KATSNIC+ +AL+A  AA+     G  G+  +  
Sbjct: 350 GVTRDATGKEVYRLALQTREQHIRRDKATSNICTAQALLANMAAMFAIYHGSHGLEHIAR 409

Query: 360 VILKNTAYLKKRLSEVA-----EIPFD------GVNFKDVLVR 391
            +   T  L + L         ++ FD      G + K+VL R
Sbjct: 410 RVHNATLILSEGLKRAGHQLQHDLFFDTLKIHCGCSVKEVLGR 452


>pir||T16734 hypothetical protein R12C12.1 - Caenorhabditis elegans
           >gi|746454|gb|AAC46780.1| (U23510) similar to glycine
           dehydrogenase [Caenorhabditis elegans]
           Length = 979
           
 Score =  236 bits (596), Expect = 4e-61
 Identities = 148/376 (39%), Positives = 216/376 (57%), Gaps = 20/376 (5%)

Query: 3   KHYIPNSAHKEEMLKEIGLSSIDELFADIPGKFIRDE--LNLPEGKSEYEVFLEMNEILG 60
           +H  P    +++ML  IG   +D+L        I+ E  L LP    EY++  E+  I  
Sbjct: 33  RHIGPRRLEQQQMLDFIGYKDLDDLTGTNVPNMIKAEKALELPAPLDEYKMLKELEAIAA 92

Query: 61  KNKTVLEMPTFLGAGTYFHYIPAHV-KYLIERSEFLTAYTPYQPEISQGMLQALFEYQSL 119
           +NK      +++G G Y   +PA + + +++   +++ YTPYQ EISQG L++L  +Q++
Sbjct: 93  QNKIYR---SYIGMGYYDTIVPAVISRNILQNIGWISQYTPYQAEISQGRLESLLNFQTM 149

Query: 120 IAELVGLPVVNASMYDWGTAMAEAALMTVRLHRGKRKKFIVPRHTHPERLQVLETYAKGP 179
           IAE+ GLP  NAS+ D  TA AEA  +  R    KR K +V    HP+ L V+ T +   
Sbjct: 150 IAEMTGLPTTNASLLDEATASAEAVALAARTT--KRNKIVVDSFCHPQNLDVIRTRSGPL 207

Query: 180 GVEIETVKWNERGQVDIEDLKEKVKDAAGVYVEIPNFFGLLEEEVREIGEIAHEAGAYFV 239
           G++IE     E    D     +KV   A V V+ PN  G + +   E+ E AH+  +  +
Sbjct: 208 GIDIEVSDSIEGYAFD-----DKV---AAVVVQYPNTEGRIHQ-FDELIESAHKNKSLVI 258

Query: 240 VGVDPTILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAV-RNDMK--LIRQMPG 296
           +  D   L I+ +PG+LGADI VG A  FG P+ +GGP AG  AV ++D K  L R +PG
Sbjct: 259 MVCDLLSLTILRSPGDLGADIAVGSAQRFGVPLGYGGPHAGFMAVAKHDAKNALGRNIPG 318

Query: 297 RLIGMTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRGIRE 356
           R+IG+TKDA G RA  + LQTREQHIRR KATSNIC+ +AL+A  +A++    GP+ + E
Sbjct: 319 RIIGVTKDANGNRALRLALQTREQHIRRDKATSNICTAQALLANMSAMYAVYHGPQRLTE 378

Query: 357 LGEVILKNTAYLKKRL 372
           +   + K+TAYL   L
Sbjct: 379 IARGVHKSTAYLAYHL 394


>gi|4504013 glycine dehydrogenase (decarboxylating; glycine decarboxylase,
           glycine cleavage system protein P) [Homo sapiens]
           >gi|87571|pir||B39521 glycine dehydrogenase
           (decarboxylating) (EC 1.4.4.2) precursor - human
           >gi|190209|gb|AAA36463.1| (M64590) glycine decarboxylase
           [Homo sapiens] >gi|219660|dbj|BAA14286.1| (D90239)
           glycine decarboxylase precursor [Homo sapiens]
           Length = 1020
           
 Score =  235 bits (594), Expect = 6e-61
 Identities = 148/403 (36%), Positives = 222/403 (54%), Gaps = 30/403 (7%)

Query: 3   KHYIPNSAHKEEMLKEIGLSSIDELFAD-IPGKF-IRDELNLPEGKSEYEVFLEMNEILG 60
           +H  P    + EML+ +GL+SIDEL    +P    ++  L + +   E E+   ++ I  
Sbjct: 66  RHIGPGDKDQREMLQTLGLASIDELIEKTVPANIRLKRPLKMEDPVCENEILATLHAISS 125

Query: 61  KNKTVLEMPTFLGAGTYFHYIPAHV-KYLIERSEFLTAYTPYQPEISQGMLQALFEYQSL 119
           KN+      +++G G Y   +P  + + L+E S ++T YTPYQPE+SQG L++L  YQ++
Sbjct: 126 KNQI---WRSYIGMGYYNCSVPQTILRNLLENSGWITQYTPYQPEVSQGRLESLLNYQTM 182

Query: 120 IAELVGLPVVNASMYDWGTAMAEAALMTVRLHRGKRKKFIVPRHTHPERLQVLETYAKGP 179
           + ++ GL + NAS+ D GTA AEA  +  R    KR+KF+V    HP+ + V++T AK  
Sbjct: 183 VCDITGLDMANASLLDEGTAAAEALQLCYR--HNKRRKFLVDPRCHPQTIAVVQTRAKYT 240

Query: 180 GVEIETVKWNERGQVDIEDLKEKVKDAAGVYVEIPNFFGLLEEEVREIGEIAHEAGAYFV 239
           GV  E     E        +    KD +GV  + P+  G +E+   E+ E AH++G+   
Sbjct: 241 GVLTELKLPCE--------MDFSGKDVSGVLFQYPDTEGKVED-FTELVERAHQSGSLAC 291

Query: 240 VGVDPTILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPGRLI 299
              D   L I+  PGE G DI +G +  FG P+ +GGP A  FAVR    L+R MPGR++
Sbjct: 292 CATDLLALCILRPPGEFGVDIALGSSQRFGVPLGYGGPHAAFFAVRES--LVRMMPGRMV 349

Query: 300 GMTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRGIRELGE 359
           G+T+DA GK  + + LQTREQHIRR KATSNIC+ +AL+A  AA+     G  G+  +  
Sbjct: 350 GVTRDATGKEVYRLALQTREQHIRRDKATSNICTAQALLANMAAMFRIYHGSHGLEHIAR 409

Query: 360 VILKNTAYLKKRLSEVA-----EIPFD------GVNFKDVLVR 391
            +   T  L + L         ++ FD      G + K+VL R
Sbjct: 410 RVHNATLILSEGLKRAGHQLQHDLFFDTLKIHCGCSVKEVLGR 452


>pir||T05309 probable glycine dehydrogenase (decarboxylating) (EC 1.4.4.2)
           F26P21.130 - Arabidopsis thaliana
           >gi|3688182|emb|CAA21210.1| (AL031804) P-Protein-like
           protein [Arabidopsis thaliana]
           >gi|7270248|emb|CAB80018.1| (AL161582) P-Protein-like
           protein [Arabidopsis thaliana]
           Length = 1037
           
 Score =  235 bits (594), Expect = 6e-61
 Identities = 149/396 (37%), Positives = 219/396 (54%), Gaps = 34/396 (8%)

Query: 8   NSAHKEE---MLKEIGLSSIDELF-ADIPGKFIRDELNLPE---GKSEYEVFLEMNEILG 60
           NSA  +E   M K  G   ID L  A +P     D +   +   G +E ++   M ++  
Sbjct: 84  NSATPDEQTHMAKFCGFDHIDSLIDATVPKSIRLDSMKFSKFDAGLTESQMIQHMVDLAS 143

Query: 61  KNKTVLEMPTFLGAGTYFHYIPAHV-KYLIERSEFLTAYTPYQPEISQGMLQALFEYQSL 119
           KNK      +F+G G Y  ++P  + + ++E   + T YTPYQ EISQG L++L  +Q++
Sbjct: 144 KNKV---FKSFIGMGYYNTHVPTVILRNIMENPAWYTQYTPYQAEISQGRLESLLNFQTV 200

Query: 120 IAELVGLPVVNASMYDWGTAMAEAALMTVRLHRGKRKKFIVPRHTHPERLQVLETYAKGP 179
           I +L GLP+ NAS+ D GTA AEA  M   + +GK+K F++  + HP+ + V +T A G 
Sbjct: 201 ITDLTGLPMSNASLLDEGTAAAEAMAMCNNILKGKKKTFVIASNCHPQTIDVCKTRADGF 260

Query: 180 GVEIETVKWNERGQVDIEDLKEKVKDAAGVYVEIPNFFGLLEEEVREIGEI---AHEAGA 236
            +++ T         D++D+     D  GV V+ P      E EV +  E    AH  G 
Sbjct: 261 DLKVVT--------SDLKDIDYSSGDVCGVLVQYPG----TEGEVLDYAEFVKNAHANGV 308

Query: 237 YFVVGVDPTILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPG 296
             V+  D   L +++ PGE GADIVVG A  FG PM +GGP A   A   + K  R MPG
Sbjct: 309 KVVMATDLLALTVLKPPGEFGADIVVGSAQRFGVPMGYGGPHAAFLATSQEYK--RMMPG 366

Query: 297 RLIGMTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRGIRE 356
           R+IG++ D+ GK+A  M +QTREQHIRR KATSNIC+ +AL+A  AA++    GP G++ 
Sbjct: 367 RIIGISVDSSGKQALRMAMQTREQHIRRDKATSNICTAQALLANMAAMYAVYHGPAGLKS 426

Query: 357 LGEVI-----LKNTAYLKKRLSEVAEIP-FDGVNFK 386
           + + +     + +    K  ++EV E+P FD V  K
Sbjct: 427 IAQRVHGLAGIFSLGLNKLGVAEVQELPFFDTVKIK 462


>sp|O49850|GCSP_FLAAN GLYCINE DEHYDROGENASE [DECARBOXYLATING], MITOCHONDRIAL PRECURSOR
           (GLYCINE DECARBOXYLASE) (GLYCINE CLEAVAGE SYSTEM
           P-PROTEIN) >gi|2894358|emb|CAB16911.1| (Z99762)
           P-protein [Flaveria anomala]
           Length = 1034
           
 Score =  235 bits (593), Expect = 8e-61
 Identities = 149/410 (36%), Positives = 220/410 (53%), Gaps = 22/410 (5%)

Query: 8   NSAHKEEMLKE---IGLSSIDELF-ADIPGKFIRDELN---LPEGKSEYEVFLEMNEILG 60
           NSA  EE  K    +G S++D L  A +P     D +      EG +E ++   M ++  
Sbjct: 80  NSATPEEQTKMAEFVGFSNLDSLIDATVPKSIRLDSMKYSKFDEGLTESQMIAHMQDLAS 139

Query: 61  KNKTVLEMPTFLGAGTYFHYIPAHV-KYLIERSEFLTAYTPYQPEISQGMLQALFEYQSL 119
           KNK      +F+G G Y   +P  + + ++E   + T YTPYQ EI+QG L++L  +Q++
Sbjct: 140 KNKI---FKSFIGMGYYNTSVPTVILRNIMENPGWYTQYTPYQAEIAQGRLESLLNFQTM 196

Query: 120 IAELVGLPVVNASMYDWGTAMAEAALMTVRLHRGKRKKFIVPRHTHPERLQVLETYAKGP 179
           I +L GLP+ NAS+ D GTA AEA  M   + +GK+K FI+  + HP+ + + +T A G 
Sbjct: 197 ITDLTGLPMSNASLLDEGTAAAEAMAMCNNIQKGKKKTFIIASNCHPQTIDICKTRADGF 256

Query: 180 GVEIETVKWNERGQVDIEDLKEKVKDAAGVYVEIPNFFGLLEEEVREIGEIAHEAGAYFV 239
            +++ T         D++D      D  GV V+ P   G L  +  E  + AH  G   V
Sbjct: 257 DLKVVT--------SDLKDFDYSSGDVCGVLVQYPGTEGEL-LDYSEFIKNAHANGVKVV 307

Query: 240 VGVDPTILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPGRLI 299
           +  D   L I++ PGELGADIVVG A  FG PM +GGP A   A   + K  R MPGR+I
Sbjct: 308 MASDLLALTILKPPGELGADIVVGSAQRFGVPMGYGGPHAAFLATSQEYK--RMMPGRII 365

Query: 300 GMTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRGIRELGE 359
           G++ D+ GK A  M +QTREQHIRR KATSNIC+ +AL+A  AA++    GP G++ + +
Sbjct: 366 GVSVDSSGKPALRMAMQTREQHIRRDKATSNICTAQALLANMAAMYGVYHGPEGLKTIAK 425

Query: 360 VILKNTAYLKKRLSEVAEIPFDGVNFKDVLVRFEKPYKEIHEELLKRNIH 409
            +          L ++  +    + F D +       K I EE  K  ++
Sbjct: 426 RVHGLAGTFAAGLKKLGTVQVQDLPFFDTVKVTCADSKAIAEEACKHKMN 475


>sp|O49852|GCSP_FLATR GLYCINE DEHYDROGENASE [DECARBOXYLATING], MITOCHONDRIAL PRECURSOR
           (GLYCINE DECARBOXYLASE) (GLYCINE CLEAVAGE SYSTEM
           P-PROTEIN) >gi|2894360|emb|CAB16916.1| (Z99767)
           P-Protein precursor [Flaveria trinervia]
           Length = 1034
           
 Score =  235 bits (592), Expect = 1e-60
 Identities = 149/410 (36%), Positives = 220/410 (53%), Gaps = 22/410 (5%)

Query: 8   NSAHKEEMLKE---IGLSSIDELF-ADIPGKFIRDELN---LPEGKSEYEVFLEMNEILG 60
           NSA  EE  K    +G S++D L  A +P     D +      EG +E ++   M ++  
Sbjct: 80  NSATPEEQTKMAEFVGFSNLDSLIDATVPKAIRLDSMKYSKFDEGLTESQMIAHMQDLAS 139

Query: 61  KNKTVLEMPTFLGAGTYFHYIPAHV-KYLIERSEFLTAYTPYQPEISQGMLQALFEYQSL 119
           KNK      +F+G G Y   +P  + + ++E   + T YTPYQ EI+QG L++L  +Q++
Sbjct: 140 KNKI---FKSFIGMGYYNTSVPTVILRNIMENPGWYTQYTPYQAEIAQGRLESLLNFQTM 196

Query: 120 IAELVGLPVVNASMYDWGTAMAEAALMTVRLHRGKRKKFIVPRHTHPERLQVLETYAKGP 179
           I +L GLP+ NAS+ D GTA AEA  M   + +GK+K FI+  + HP+ + + +T A G 
Sbjct: 197 ITDLTGLPMSNASLLDEGTAAAEAMAMCNNIQKGKKKTFIIASNCHPQTIDICKTRADGF 256

Query: 180 GVEIETVKWNERGQVDIEDLKEKVKDAAGVYVEIPNFFGLLEEEVREIGEIAHEAGAYFV 239
            +++ T         D++D      D  GV V+ P   G L  +  E  + AH  G   V
Sbjct: 257 DLKVVT--------SDLKDFDYSSGDVCGVLVQYPGTEGEL-LDYSEFIKNAHANGVKVV 307

Query: 240 VGVDPTILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPGRLI 299
           +  D   L I++ PGELGADIVVG A  FG PM +GGP A   A   + K  R MPGR+I
Sbjct: 308 MASDLLALTILKPPGELGADIVVGSAQRFGVPMGYGGPHAAFLATSQEYK--RMMPGRII 365

Query: 300 GMTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRGIRELGE 359
           G++ D+ GK A  M +QTREQHIRR KATSNIC+ +AL+A  AA++    GP G++ + +
Sbjct: 366 GVSVDSSGKPALRMAMQTREQHIRRDKATSNICTAQALLANMAAMYGVYHGPEGLKTIAK 425

Query: 360 VILKNTAYLKKRLSEVAEIPFDGVNFKDVLVRFEKPYKEIHEELLKRNIH 409
            +          L ++  +    + F D +       K I EE  K  ++
Sbjct: 426 RVHGLAGTFAAGLKKLGTVQVQDLPFFDTVKVTCADSKAIAEEAYKHKMN 475


>sp|Q09785|GCSP_SCHPO PUTATIVE GLYCINE DEHYDROGENASE [DECARBOXYLATING], MITOCHONDRIAL
           PRECURSOR (GLYCINE DECARBOXYLASE) (GLYCINE CLEAVAGE
           SYSTEM P-PROTEIN) >gi|2130270|pir||S62435 probable
           glycine dehydrogenase (decarboxylating) - fission yeast
           (Schizosaccharomyces pombe) >gi|7492605|pir||T37641
           probable glycine dehydrogenase (decarboxylating) -
           fission yeast (Schizosaccharomyces pombe)
           >gi|1008991|emb|CAA91099.1| (Z54308) putative glycine
           dehydrogenase (decarboxylating) [Schizosaccharomyces
           pombe]
           Length = 1017
           
 Score =  234 bits (591), Expect = 1e-60
 Identities = 139/385 (36%), Positives = 209/385 (54%), Gaps = 27/385 (7%)

Query: 3   KHYIPNSAHKEEMLKEIGLSSIDELFADIPGKFIR--------------DELNLPEGKSE 48
           +H  P+   ++  L+ +G    D    D+    +R              +E N P   SE
Sbjct: 52  RHIGPSKTDQQYQLESLGYKDFDSFLKDVIPDSVRTPESQLMAFGSVNPNEKNPPVNYSE 111

Query: 49  YEVFLEMNEILGKNKTVLEMPTFLGAGTYFHYIPAHV-KYLIERSEFLTAYTPYQPEISQ 107
            E     N +  +NK +    +F+G G Y   +PA + + ++E  E+ T YTPYQ EISQ
Sbjct: 112 SEFTTLANNVANQNKLI---KSFIGMGYYNVKLPAAIQRNVLENPEWYTQYTPYQAEISQ 168

Query: 108 GMLQALFEYQSLIAELVGLPVVNASMYDWGTAMAEAALMTVRLHRGKRKKFIVPRHTHPE 167
           G L+++  YQ++IA+L GL + NAS+ D GTA  EA +M +   + KRK F+V ++ +P 
Sbjct: 169 GRLESMMNYQTMIADLTGLSISNASLLDEGTAAGEAMVMLMANDKKKRKTFLVDKNIYPN 228

Query: 168 RLQVLETYAKGPGVEIETVKWNERGQVDIEDLKEKVKDAAGVYVEIPNFFGLLEEEVREI 227
            L VL T A G G++IE         +  E + +  K   G++V+ P   G +  +   +
Sbjct: 229 TLSVLRTRASGFGIKIEL------DNITPELITKSAKHVFGIFVQYPAADGSI-FDYGHL 281

Query: 228 GEIAHEAGAYFVVGVDPTILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVRND 287
              A     + V   D   L I+++PGE GAD+ VG    FG PM +GGP AG FA   +
Sbjct: 282 AATARSFNMHVVAATDLLALTILKSPGEWGADVAVGSTQRFGLPMGYGGPHAGFFACSEE 341

Query: 288 MKLIRQMPGRLIGMTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIA 347
            K  R++PGRLIG++KD     A+ + LQTREQHIRR KATSNIC+ +AL+A  +A +  
Sbjct: 342 FK--RKIPGRLIGLSKDRLENPAYRLALQTREQHIRREKATSNICTAQALLANMSAFYAI 399

Query: 348 SLGPRGIRELGEVILKNTAYLKKRL 372
             GP G++E+   I  +T++LK  L
Sbjct: 400 YHGPNGLQEIANRIYASTSFLKSAL 424


>sp|P49362|GCSB_FLAPR GLYCINE DEHYDROGENASE [DECARBOXYLATING] B, MITOCHONDRIAL PRECURSOR
           (GLYCINE DECARBOXYLASE B) (GLYCINE CLEAVAGE SYSTEM
           P-PROTEIN B) >gi|2130012|pir||S63536
           aminomethyltransferase (EC 2.1.2.10) gdcsPB precursor -
           Flaveria pringlei >gi|1000489|emb|CAA91000.1| (Z54239)
           P-protein precursor of glycine cleavage system [Flaveria
           pringlei]
           Length = 1034
           
 Score =  232 bits (586), Expect = 6e-60
 Identities = 148/410 (36%), Positives = 218/410 (53%), Gaps = 22/410 (5%)

Query: 8   NSAHKEEMLKE---IGLSSIDELF-ADIPGKFIRDELN---LPEGKSEYEVFLEMNEILG 60
           NSA  EE  K    +G  ++D L  A +P     D +      EG +E ++   M ++  
Sbjct: 80  NSATPEEQTKMAEFVGFPNLDSLIDATVPKSIRLDSMKYSKFDEGLTESQMIAHMQDLAS 139

Query: 61  KNKTVLEMPTFLGAGTYFHYIPAHV-KYLIERSEFLTAYTPYQPEISQGMLQALFEYQSL 119
           KNK      +F+G G Y   +P  + + ++E   + T YTPYQ EI+QG L++L  +Q++
Sbjct: 140 KNKI---FKSFIGMGYYNTSVPTVILRNIMENPGWYTQYTPYQAEIAQGRLESLLNFQTM 196

Query: 120 IAELVGLPVVNASMYDWGTAMAEAALMTVRLHRGKRKKFIVPRHTHPERLQVLETYAKGP 179
           I +L GLP+ NAS+ D GTA AEA  M   + +GK+K FI+  + HP+ + + +T A G 
Sbjct: 197 ITDLTGLPMSNASLLDEGTAAAEAMAMCNNIQKGKKKTFIIASNCHPQTIDICKTRADGF 256

Query: 180 GVEIETVKWNERGQVDIEDLKEKVKDAAGVYVEIPNFFGLLEEEVREIGEIAHEAGAYFV 239
            +++ T         D++D      D  GV V+ P   G L  +  E  + AH  G   V
Sbjct: 257 DLKVVT--------SDLKDFDYSSGDVCGVLVQYPGTEGEL-LDYSEFIKNAHANGVKVV 307

Query: 240 VGVDPTILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPGRLI 299
           +  D   L I++ PGELGADIVVG A  FG PM +GGP A   A   + K  R MPGR+I
Sbjct: 308 MASDLLALTILKPPGELGADIVVGSAQRFGVPMGYGGPHAAFLATSQEYK--RMMPGRII 365

Query: 300 GMTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRGIRELGE 359
           G++ D+ GK A  M +QTREQHIRR KATSNIC+ +AL+A  AA+     GP G++ + +
Sbjct: 366 GVSVDSSGKPALRMAMQTREQHIRRDKATSNICTAQALLANMAAMFGVYHGPEGLKTIAK 425

Query: 360 VILKNTAYLKKRLSEVAEIPFDGVNFKDVLVRFEKPYKEIHEELLKRNIH 409
            +          L ++  +    + F D +       K I EE  K  ++
Sbjct: 426 RVHGLAGTFASGLKKLGTVQVQDLPFFDTVKVTCADSKAIAEEAYKHKMN 475


>pir||T02615 probable glycine dehydrogenase (decarboxylating) (EC 1.4.4.2)
           T19L18.11 - Arabidopsis thaliana
           >gi|3413705|gb|AAC31228.1| (AC004747) putative glycine
           dehydrogenase [Arabidopsis thaliana]
           Length = 1044
           
 Score =  232 bits (586), Expect = 6e-60
 Identities = 142/364 (39%), Positives = 204/364 (56%), Gaps = 29/364 (7%)

Query: 8   NSAHKEE---MLKEIGLSSIDELFADIPGKFIR-DELNLP----EGKSEYEVFLEMNEIL 59
           NSA  +E   M    G  +++ L      K IR D +       EG +E ++   M+++ 
Sbjct: 89  NSATPDEQAQMANYCGFDNLNTLIDSTVPKSIRLDSMKFSGIFDEGLTESQMIEHMSDLA 148

Query: 60  GKNKTVLEMPTFLGAGTY-FHYIPAHVKYLIERSEFLTAYTPYQPEISQGMLQALFEYQS 118
            KNK      +F+G G Y  H  P  ++ ++E   + T YTPYQ EISQG L++L  YQ+
Sbjct: 149 SKNKV---FKSFIGMGYYNTHVPPVILRNIMENPAWYTQYTPYQAEISQGRLESLLNYQT 205

Query: 119 LIAELVGLPVVNASMYDWGTAMAEAALMTVRLHRGKRKKFIVPRHTHPERLQVLETYAKG 178
           +I +L GLP+ NAS+ D GTA AEA  M   + +GK+K F++  + HP+ + V +T A G
Sbjct: 206 VITDLTGLPMSNASLLDEGTAAAEAMAMCNNILKGKKKTFVIASNCHPQTIDVCKTRADG 265

Query: 179 PGVEIETVKWNERGQVDIEDLKEKVKDAAGVYVEIPNFFGLLEEEVREIGEI---AHEAG 235
             +++ T        VDI+D+     D  GV V+ P      E EV + GE    AH  G
Sbjct: 266 FDLKVVT--------VDIKDVDYSSGDVCGVLVQYPG----TEGEVLDYGEFVKNAHANG 313

Query: 236 AYFVVGVDPTILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQMP 295
              V+  D   L +++ PGE GADIVVG    FG PM +GGP A   A   + K  R MP
Sbjct: 314 VKVVMATDLLALTMLKPPGEFGADIVVGSGQRFGVPMGYGGPHAAFLATSQEYK--RMMP 371

Query: 296 GRLIGMTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRGIR 355
           GR+IG++ D+ GK+A  M +QTREQHIRR KATSNIC+ +AL+A   A++    GP G++
Sbjct: 372 GRIIGVSVDSSGKQALRMAMQTREQHIRRDKATSNICTAQALLANMTAMYAVYHGPEGLK 431

Query: 356 ELGE 359
            + +
Sbjct: 432 SIAQ 435


>sp|P26969|GCSP_PEA GLYCINE DEHYDROGENASE [DECARBOXYLATING], MITOCHONDRIAL PRECURSOR
           (GLYCINE DECARBOXYLASE) (GLYCINE CLEAVAGE SYSTEM
           P-PROTEIN) >gi|282926|pir||A42109 glycine dehydrogenase
           (decarboxylating) (EC 1.4.4.2) component P precursor -
           garden pea >gi|20741|emb|CAA42443.1| (X59773) component
           of aminomethyltransferase [Pisum sativum]
           Length = 1057
           
 Score =  231 bits (584), Expect = 9e-60
 Identities = 141/363 (38%), Positives = 207/363 (56%), Gaps = 28/363 (7%)

Query: 8   NSAHKEE---MLKEIGLSSIDELF-ADIPGKFIRDELNLPE---GKSEYEVFLEMNEILG 60
           NSA  +E   M + +G  ++D L  A +P      E+   +   G +E ++   M ++  
Sbjct: 103 NSATPDEQTKMAESVGFDTLDSLVDATVPKSIRLKEMKFNKFDGGLTEGQMIEHMKDLAS 162

Query: 61  KNKTVLEMPTFLGAGTY-FHYIPAHVKYLIERSEFLTAYTPYQPEISQGMLQALFEYQSL 119
           KNK      +F+G G Y  H  P  ++ ++E   + T YTPYQ EISQG L++L  +Q++
Sbjct: 163 KNKV---FKSFIGMGYYNTHVPPVILRNIMENPAWYTQYTPYQAEISQGRLESLLNFQTM 219

Query: 120 IAELVGLPVVNASMYDWGTAMAEAALMTVRLHRGKRKKFIVPRHTHPERLQVLETYAKGP 179
           I +L GLP+ NAS+ D GTA AEA  M   + +GK+K FI+  + HP+ + + +T A G 
Sbjct: 220 ITDLTGLPMSNASLLDEGTAAAEAMSMCNNIQKGKKKTFIIASNCHPQTIDICQTRADGF 279

Query: 180 GVEIETVKWNERGQVDIEDLKEKVKDAAGVYVEIPNFFGLLEEEVREIGEI---AHEAGA 236
            +++  VK       D++D+  K  D  GV V+ P      E EV + GE    AH    
Sbjct: 280 ELKV-VVK-------DLKDIDYKSGDVCGVLVQYPG----TEGEVLDYGEFIKKAHANEV 327

Query: 237 YFVVGVDPTILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPG 296
             V+  D   L +++ PGE GADIVVG A  FG PM +GGP A   A   + K  R MPG
Sbjct: 328 KVVMASDLLALTVLKPPGEFGADIVVGSAQRFGVPMGYGGPHAAFLATSQEYK--RMMPG 385

Query: 297 RLIGMTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRGIRE 356
           R+IG++ D+ GK+A  M +QTREQHIRR KATSNIC+ +AL+A  AA++    GP G++ 
Sbjct: 386 RIIGVSVDSSGKQALRMAMQTREQHIRRDKATSNICTAQALLANMAAMYAVYHGPEGLKA 445

Query: 357 LGE 359
           + +
Sbjct: 446 IAQ 448


>pir||S40216 P protein - Flaveria pringlei >gi|438003|emb|CAA81076.1| (Z25857) P
           protein [Flaveria pringlei]
           Length = 1037
           
 Score =  231 bits (583), Expect = 1e-59
 Identities = 147/410 (35%), Positives = 218/410 (52%), Gaps = 22/410 (5%)

Query: 8   NSAHKEEMLKE---IGLSSIDELF-ADIPGKFIRDELN---LPEGKSEYEVFLEMNEILG 60
           NSA  EE  K    +G  ++D L  A +P     D +      EG +E ++   M ++  
Sbjct: 83  NSATPEEQTKMAEFVGFPNLDSLIDATVPKSIRLDSMKYSKFDEGLTESQMIAHMQDLAS 142

Query: 61  KNKTVLEMPTFLGAGTYFHYIPAHV-KYLIERSEFLTAYTPYQPEISQGMLQALFEYQSL 119
           KNK      +F+G G Y   +P  + + ++E   + T YTPYQ EI+QG L++L  +Q++
Sbjct: 143 KNKI---FKSFIGMGYYNTSVPTVILRNIMENPGWYTQYTPYQAEIAQGRLESLLNFQTM 199

Query: 120 IAELVGLPVVNASMYDWGTAMAEAALMTVRLHRGKRKKFIVPRHTHPERLQVLETYAKGP 179
           + +L GLP+ NAS+ D GTA AEA  M   + +GK+K FI+  + HP+ + + +T A G 
Sbjct: 200 VTDLTGLPMSNASLLDEGTAAAEAMAMCNNIQKGKKKTFIIASNCHPQTIDICKTRADGF 259

Query: 180 GVEIETVKWNERGQVDIEDLKEKVKDAAGVYVEIPNFFGLLEEEVREIGEIAHEAGAYFV 239
            +++ T         D++D      D  GV V+ P   G L  +  E  + AH  G   V
Sbjct: 260 DLKVVT--------SDLKDFDYSSGDVCGVLVQYPGTEGEL-LDYSEFIKNAHANGVKVV 310

Query: 240 VGVDPTILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPGRLI 299
           +  D   L I++ PGELGADIVVG A  FG PM +GGP A   A   + K  R MPGR+I
Sbjct: 311 MASDLLALTILKPPGELGADIVVGSAQRFGVPMGYGGPHAAFLATSQEYK--RMMPGRII 368

Query: 300 GMTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRGIRELGE 359
           G++ D+ GK A  M +QTREQHIRR KATSNIC+ +AL+A  AA+     GP G++ + +
Sbjct: 369 GVSVDSSGKPALRMAMQTREQHIRRDKATSNICTAQALLANMAAMFGVYHGPEGLKTIAK 428

Query: 360 VILKNTAYLKKRLSEVAEIPFDGVNFKDVLVRFEKPYKEIHEELLKRNIH 409
            +          L ++  +    + F D +       K I EE  K  ++
Sbjct: 429 RVHGLAGTFAAGLKKLGTVQVQDLPFFDTVKVTCVDSKAIAEEAYKHKMN 478


>sp|P49361|GCSA_FLAPR GLYCINE DEHYDROGENASE [DECARBOXYLATING] A, MITOCHONDRIAL PRECURSOR
           (GLYCINE DECARBOXYLASE A) (GLYCINE CLEAVAGE SYSTEM
           P-PROTEIN A) >gi|2130011|pir||S63535
           aminomethyltransferase (EC 2.1.2.10) gdcsPA precursor -
           Flaveria pringlei >gi|608712|emb|CAA85353.1| (Z36879)
           P-protein of the glycine cleavage system [Flaveria
           pringlei]
           Length = 1037
           
 Score =  231 bits (583), Expect = 1e-59
 Identities = 147/410 (35%), Positives = 218/410 (52%), Gaps = 22/410 (5%)

Query: 8   NSAHKEEMLKE---IGLSSIDELF-ADIPGKFIRDELN---LPEGKSEYEVFLEMNEILG 60
           NSA  EE  K    +G  ++D L  A +P     D +      EG +E ++   M ++  
Sbjct: 83  NSATPEEQTKMAEFVGFPNLDSLIDATVPKSIRLDSMKYSKFDEGLTESQMIAHMQDLAS 142

Query: 61  KNKTVLEMPTFLGAGTYFHYIPAHV-KYLIERSEFLTAYTPYQPEISQGMLQALFEYQSL 119
           KNK      +F+G G Y   +P  + + ++E   + T YTPYQ EI+QG L++L  +Q++
Sbjct: 143 KNKI---FKSFIGMGYYNTSVPTVILRNIMENPGWYTQYTPYQAEIAQGRLESLLNFQTM 199

Query: 120 IAELVGLPVVNASMYDWGTAMAEAALMTVRLHRGKRKKFIVPRHTHPERLQVLETYAKGP 179
           + +L GLP+ NAS+ D GTA AEA  M   + +GK+K FI+  + HP+ + + +T A G 
Sbjct: 200 VTDLTGLPMSNASLLDEGTAAAEAMAMCNNIQKGKKKTFIIASNCHPQTIDICKTRADGF 259

Query: 180 GVEIETVKWNERGQVDIEDLKEKVKDAAGVYVEIPNFFGLLEEEVREIGEIAHEAGAYFV 239
            +++ T         D++D      D  GV V+ P   G L  +  E  + AH  G   V
Sbjct: 260 DLKVVT--------SDLKDFDYSSGDVCGVLVQYPGTEGEL-LDYSEFIKNAHANGVKVV 310

Query: 240 VGVDPTILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPGRLI 299
           +  D   L I++ PGELGADIVVG A  FG PM +GGP A   A   + K  R MPGR+I
Sbjct: 311 MASDLLALTILKPPGELGADIVVGSAQRFGVPMGYGGPHAAFLATSQEYK--RMMPGRII 368

Query: 300 GMTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRGIRELGE 359
           G++ D+ GK A  M +QTREQHIRR KATSNIC+ +AL+A  AA+     GP G++ + +
Sbjct: 369 GVSVDSSGKPALRMAMQTREQHIRRDKATSNICTAQALLANMAAMFGVYHGPEGLKTIAK 428

Query: 360 VILKNTAYLKKRLSEVAEIPFDGVNFKDVLVRFEKPYKEIHEELLKRNIH 409
            +          L ++  +    + F D +       K I EE  K  ++
Sbjct: 429 RVHGLAGTFAAGLKKLGTVQVQDLPFFDTVKVTCVDSKAIAEEAYKHKMN 478


>gi|6323843 Glycine decarboxylase complex (P-subunit), glycine synthase
           (P-subunit), Glycine cleavage system (P-subunit); Gcv2p
           [Saccharomyces cerevisiae]
           >gi|1346120|sp|P49095|GCSP_YEAST GLYCINE DEHYDROGENASE
           [DECARBOXYLATING], MITOCHONDRIAL PRECURSOR (GLYCINE
           DECARBOXYLASE) (GLYCINE CLEAVAGE SYSTEM P-PROTEIN)
           >gi|1078211|pir||S50917 aminomethyltransferase (EC
           2.1.2.10) - yeast (Saccharomyces cerevisiae)
           >gi|642281|emb|CAA87810.1| (Z47815) putative glycine
           dehydrogenase [Saccharomyces cerevisiae]
           >gi|676871|gb|AAB18933.1| (U20641) glycine decarboxylase
           [Saccharomyces cerevisiae] >gi|1589242|prf||2210375A Gly
           decarboxylase:SUBUNIT=P [Saccharomyces cerevisiae]
           Length = 1034
           
 Score =  228 bits (576), Expect = 8e-59
 Identities = 138/379 (36%), Positives = 216/379 (56%), Gaps = 25/379 (6%)

Query: 3   KHYIPNSAHKEEMLKEIGLSSIDELFADI--PGKFIRDELNLP---EGKSEYEVFLEMNE 57
           +H  P+ +  ++MLK +G S ++    ++  P    R  L L    +G  E E+   + +
Sbjct: 70  RHLGPSPSDVKKMLKTMGYSDLNAFIEELVPPNILKRRPLKLEAPSKGFCEQEMLQHLEK 129

Query: 58  ILGKNKTVLEMPTFLGAGTYFHYIPAHV-KYLIERSEFLTAYTPYQPEISQGMLQALFEY 116
           I  KN    ++  F+G G Y   +P  + + L+E  E+ T+YTPYQPEISQG L+AL  +
Sbjct: 130 IANKNH--YKVKNFIGKGYYGTILPPVIQRNLLESPEWYTSYTPYQPEISQGRLEALLNF 187

Query: 117 QSLIAELVGLPVVNASMYDWGTAMAEAALMTVRLHRGKRKKFIVPRHTHPERLQVLETYA 176
           Q+++++L GLPV NAS+ D GTA  EA L++  + R K+ K+++ +  H +   VL T A
Sbjct: 188 QTVVSDLTGLPVANASLLDEGTAAGEAMLLSFNISRKKKLKYVIDKKLHQQTKSVLHTRA 247

Query: 177 KGPGVEIETVKWNERGQVDIEDLKEKV-----KDAAGVYVEIPNFFG--LLEEEVREIGE 229
           K   +EI         +VD  D+K+ V      D +G  V+ P   G  L  + ++++ +
Sbjct: 248 KPFNIEII--------EVDCSDIKKAVDVLKNPDVSGCLVQYPATDGSILPPDSMKQLSD 299

Query: 230 IAHEAGAYFVVGVDPTILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVRNDMK 289
             H   +   V  D   L +++ P   GADIV+G +  FG PM +GGP A  FAV +  K
Sbjct: 300 ALHSHKSLLSVASDLMALTLLKPPAHYGADIVLGSSQRFGVPMGYGGPHAAFFAVID--K 357

Query: 290 LIRQMPGRLIGMTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASL 349
           L R++PGR++G++KD  GK A  + LQTREQHI+R KATSNIC+ +AL+A  A+ +    
Sbjct: 358 LNRKIPGRIVGISKDRLGKTALRLALQTREQHIKRDKATSNICTAQALLANVASSYCVYH 417

Query: 350 GPRGIRELGEVILKNTAYL 368
           GP+G++ +   I   T+ L
Sbjct: 418 GPKGLQNISRRIFSLTSIL 436


>pir||T44754 probable glycine dehydrogenase (decarboxylating) (EC 1.4.4.2)
           [imported] - Mycobacterium leprae
           >gi|2578379|emb|CAA15464.1| (AL008609) glycine
           dehydrogenase (decarboxylating) [Mycobacterium leprae]
           Length = 952
           
 Score =  226 bits (570), Expect = 4e-58
 Identities = 156/456 (34%), Positives = 222/456 (48%), Gaps = 37/456 (8%)

Query: 2   AKHYIPNSAHKEEMLKEIGLSSIDELFADIPGKFIRDELN----------LPEGKSEYEV 51
           A+H  PNS     ML  IG+ S+D+L A      I D +           LP   +E E 
Sbjct: 15  ARHIGPNSEDVATMLAVIGVESLDDLAAKAVPSDILDNVTDTGVAPGLDRLPPPATESET 74

Query: 52  FLEMNEILGKNKTVLEMPTFLGAGTYFHYIPAHV-KYLIERSEFLTAYTPYQPEISQGML 110
             E+  +   N   + M   +G G Y    PA + + ++E   + T YTPYQPEISQG L
Sbjct: 75  LAELGALARANTVAVSM---IGQGYYDTLTPAVLSRNILENPAWYTPYTPYQPEISQGRL 131

Query: 111 QALFEYQSLIAELVGLPVVNASMYDWGTAMAEAALMTVRLHRGKRKKFIVPRHTHPERLQ 170
           +AL  +Q+L+++L GL + NASM D GTA AEA  +  R  R    + +V      + + 
Sbjct: 132 EALLNFQTLVSDLTGLEIANASMLDEGTAAAEAMTLMYRAARSTASRVVVDVDVFAQTVA 191

Query: 171 VLETYAKGPGVEIETVKWNERGQVDIEDLKEKVKDAA--GVYVEIPNFFGLLEEEVREIG 228
           V  T AK  G++I            + DL+E + D    GV  ++P   G + +    I 
Sbjct: 192 VFATRAKPLGIDIV-----------VADLREGLPDGEFFGVITQLPGASGRITDWTALIA 240

Query: 229 EIAHEAGAYFVVGVDPTILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVRNDM 288
           + AH  GA   VG D   L ++  PGE+GAD+  G    FG PM FGGP AG  A+    
Sbjct: 241 Q-AHSRGALVAVGADLLALTLITPPGEIGADVAFGTTQRFGVPMGFGGPHAGYLALHT-- 297

Query: 289 KLIRQMPGRLIGMTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIAS 348
           K  RQ+PGRL+G++ D++G  A+ + LQTREQHIRR KATSNIC+ + L+AV AA++ + 
Sbjct: 298 KHARQLPGRLVGVSVDSDGTPAYRLALQTREQHIRRDKATSNICTAQVLLAVMAAMYASY 357

Query: 349 LGPRGIRELGEVILKNTAYLKKRLSEVAEIPFDGVNFKDVLVRFEKPYKEIHEELLKRNI 408
            G  G+  +   +      L   LS           F  VL R      +I     +R I
Sbjct: 358 HGAEGLTGIARRVHAQARALAAGLSAAGVEVVHQAFFDTVLARVPGRTVQIQGAAKERGI 417

Query: 409 HGGYYVGKHFPELGESALFAATETTRKEWVDALISA 444
           +     G H          A  E T  E + A+++A
Sbjct: 418 NVWLVDGDH-------VSVACDEATTDEHITAVLAA 446


>pir||E75352 glycine cleavage system P protein - Deinococcus radiodurans
           (strain R1) >gi|6459582|gb|AAF11360.1|AE002021_9
           (AE002021) glycine cleavage system P protein
           [Deinococcus radiodurans]
           Length = 949
           
 Score =  225 bits (568), Expect = 7e-58
 Identities = 148/391 (37%), Positives = 206/391 (51%), Gaps = 23/391 (5%)

Query: 3   KHYIPNSAHKEEMLKEIGLSSIDELF-ADIPGKFIRD-ELNLPEGKSEYEVFLEMNEILG 60
           +H  P+ A + EML  +G+SS+DEL    +P     D EL+   G +E +   E+  +  
Sbjct: 17  RHIGPSEAEQAEMLGVLGVSSLDELTQTTLPAAIQFDGELHTGPGMTEAQALAELKAVAQ 76

Query: 61  KNKTVLEMPTFLGAGTYFHYIPAHVKYLIERSEFLTAYTPYQPEISQGMLQALFEYQSLI 120
           KNK          AGT     P  ++ ++E   + TAYTPYQ EISQG L+ L  +Q  +
Sbjct: 77  KNKVFRSYIGMGYAGT--DVPPVILRNMLENPGWYTAYTPYQAEISQGRLEMLLNFQQTV 134

Query: 121 AELVGLPVVNASMYDWGTAMAEAALMTVRLHRGKRKK-FIVPRHTHPERLQVLETYAKGP 179
            ++ G+PV NAS+ D  TA AEA  +  R  + K    F V  + HP+ + V++T A+  
Sbjct: 135 QDMTGMPVSNASLLDEATAAAEAMTLAKRQSKNKGSNVFFVADNVHPQTMDVVKTRAEYF 194

Query: 180 GVEIETVKWNERGQVDIEDLKEKVKDAAGVYVEIPNFFGLLEEEVREIGEIAHEAGAYFV 239
           G E++T      G  D        + A G  V+ P   G +   +  I E AH  GA  +
Sbjct: 195 GFEVQT------GSADAIP-----EGAFGALVQYPGTHGEVLN-LAPIAEKAHTQGAALI 242

Query: 240 VGVDPTILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPGRLI 299
           V  D     ++  PGE GADIVVG A  FG PM FGGP A   A +   +  R MPGR+I
Sbjct: 243 VATDLLACALLTPPGEQGADIVVGSAQRFGVPMGFGGPHAAFLACQKGFE--RSMPGRVI 300

Query: 300 GMTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRGIRELGE 359
           G++KD  G  A  M +QTREQHIRR KATSNIC+ +AL+A  AA +    GP GI+ + E
Sbjct: 301 GVSKDVRGNTALRMAMQTREQHIRREKATSNICTAQALLANMAAAYAVWHGPEGIKTIAE 360

Query: 360 VILKNTAYLKKRLSEVA----EIPFDGVNFK 386
            + + T  L K L +      E  FD + F+
Sbjct: 361 RVHRLTGILAKALQDAGIKANETFFDTLTFE 391


 Score = 80.0 bits (194), Expect = 5e-14
 Identities = 95/376 (25%), Positives = 162/376 (42%), Gaps = 57/376 (15%)

Query: 100 PYQPEI-SQGMLQALFEYQSLIAELVGLPVVNASMYDWGTAMAE-AALMTVRLH---RGK 154
           P+ PE  +QG  + L E +  +A++ G   V  SM     A  E A L+ +R +   RG+
Sbjct: 524 PFAPESQTQGYAEMLAELERWLADITGYDAV--SMQPNSGAQGEYAGLLVIRKYHEARGE 581

Query: 155 --RKKFIVPRHTHPERLQVLETYAKGPGVEIETVKWNERGQVDIEDLKEKVK----DAAG 208
             R   ++P   H          A   G+++  VK +E+G +D +DLK + +      A 
Sbjct: 582 AHRNICLIPASAHGTN----PASAAMMGMQVVVVKTDEQGNIDFDDLKAQAEAHSDHLAA 637

Query: 209 VYVEIPNFFGLLEEEVREIGEIAHE-AGAYFVVGVDPTILGIVEAPGELGADIV-VGEAS 266
           + +  P+  G+ EE VR++ ++ H+  G  ++ G +   +  V  PG +G D+  +    
Sbjct: 638 LMITYPSTHGVYEENVRDVCDLIHQHGGQVYLDGANMNAMVGVAKPGLIGGDVSHLNLHK 697

Query: 267 YFGNPMNFGGPRAGIFAVRNDMKLIRQMPGRLIGMTKDAEGKRAFVMTLQTREQHIRRAK 326
            F  P   GGP  G   V+    L   +P   +  T D+                     
Sbjct: 698 TFAIPHGGGGPGMGPIGVK--AHLAPFLPNHAVAPTSDSH------------------TG 737

Query: 327 ATSNICSNEALVAVAAAIHIASLGPRGIRELGEVILKNTAYLKKRLSEVAEIPFDGVNFK 386
           A S      A +   + ++I  LG  G+R+  +V L N  Y+ KRLS    + + G   K
Sbjct: 738 AVSAAPYGSASILPISYLYIKLLGAAGLRQSTQVALLNANYIAKRLSGAFPVLYSG---K 794

Query: 387 DVLVRFE-----KPYKE----IHEELLKRNIHGGYYV-GKHFPELGESALFAATETTRK- 435
              V  E     +P K+      E++ KR +  G++     FP  G + +   TE+  K 
Sbjct: 795 GGRVAHECILDIRPLKQESGVSEEDIAKRLMDYGFHAPTMSFPVPG-TLMIEPTESEPKA 853

Query: 436 ---EWVDALISALREV 448
               +VDA+++  RE+
Sbjct: 854 ELDRFVDAMLNIRREI 869


>pir||A39521 glycine dehydrogenase (decarboxylating) (EC 1.4.4.2) precursor -
           chicken
           Length = 1003
           
 Score =  224 bits (566), Expect = 1e-57
 Identities = 144/414 (34%), Positives = 220/414 (52%), Gaps = 25/414 (6%)

Query: 3   KHYIPNSAHKEEMLKEIGLSSIDELF-ADIPGKF-IRDELNLPEGKSEYEVFLEMNEILG 60
           +H  P    K EML  +G+ S++EL    IP    +R  L + +   E E+   +  I  
Sbjct: 55  RHIGPREREKREMLSAVGVQSVEELMDKTIPASIRLRRPLRMDDHVVENEILETLYNIAS 114

Query: 61  KNKTVLEMPTFLGAGTYFHYIPAHV-KYLIERSEFLTAYTPYQPEISQGMLQALFEYQSL 119
           KNK      +++G G Y   +P  + + L+E + ++T YTPYQPE+SQG L++L  YQ++
Sbjct: 115 KNKI---WRSYIGMGYYNCSVPQPIARNLLENAGWVTQYTPYQPEVSQGRLESLLNYQTM 171

Query: 120 IAELVGLPVVNASMYDWGTAMAEAALMTVRLHRGKRKKFIVPRHTHPERLQVLETYAKGP 179
           + ++ G+ V NAS+ D GTA AEA  +  R  + KR+KF +    HP+      T A   
Sbjct: 172 VCDITGMDVANASLLDEGTAAAEAMQLCHR--QNKRRKFYIDARCHPQ------TIANYT 223

Query: 180 GVEIETVKWNERGQVDIEDLKEKVKDAAGVYVEIPNFFGLLEEEVREIGEIAHEAGAYFV 239
           GV  E    +E        +    KD +GV  + P+  G +E+   E+ E AH+ G    
Sbjct: 224 GVITELKLPHE--------MDFSGKDVSGVLFQYPDTEGKVED-FSELIERAHQNGTLAC 274

Query: 240 VGVDPTILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPGRLI 299
              D   L I++ PGE G D+V+G +  FG P+ +GGP A  FAV+ +  L+R MPGR++
Sbjct: 275 CATDLLALCILKPPGEFGVDVVLGSSQRFGVPLCYGGPHAAFFAVKEN--LVRMMPGRMV 332

Query: 300 GMTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRGIRELGE 359
           G+T+DA GK  + + LQTREQHIRR KATSNIC+ +AL+A  AA++    G  G++++  
Sbjct: 333 GVTRDANGKEVYRLALQTREQHIRRDKATSNICTAQALLANMAAMYGVYHGSDGLKDIAR 392

Query: 360 VILKNTAYLKKRLSEVAEIPFDGVNFKDVLVRFEKPYKEIHEELLKRNIHGGYY 413
            +   T  L + L          + F  + V      KE+ +    R I+   Y
Sbjct: 393 RVHNATLILAEGLRRAGHKLHHDLFFDTLTVTCGCSVKEVLDRAALRKINVRIY 446


>sp|P15505|GCSP_CHICK GLYCINE DEHYDROGENASE [DECARBOXYLATING], MITOCHONDRIAL PRECURSOR
           (GLYCINE DECARBOXYLASE) (GLYCINE CLEAVAGE SYSTEM
           P-PROTEIN) >gi|212585|gb|AAA49029.1| (M64402) glycine
           decarboxylase [Gallus gallus] >gi|222821|dbj|BAA14313.1|
           (D90266) glycine decarboxylase precursor [Gallus gallus]
           Length = 1004
           
 Score =  224 bits (566), Expect = 1e-57
 Identities = 144/414 (34%), Positives = 220/414 (52%), Gaps = 25/414 (6%)

Query: 3   KHYIPNSAHKEEMLKEIGLSSIDELF-ADIPGKF-IRDELNLPEGKSEYEVFLEMNEILG 60
           +H  P    K EML  +G+ S++EL    IP    +R  L + +   E E+   +  I  
Sbjct: 56  RHIGPREREKREMLSAVGVQSVEELMDKTIPASIRLRRPLRMDDHVVENEILETLYNIAS 115

Query: 61  KNKTVLEMPTFLGAGTYFHYIPAHV-KYLIERSEFLTAYTPYQPEISQGMLQALFEYQSL 119
           KNK      +++G G Y   +P  + + L+E + ++T YTPYQPE+SQG L++L  YQ++
Sbjct: 116 KNKI---WRSYIGMGYYNCSVPQPIARNLLENAGWVTQYTPYQPEVSQGRLESLLNYQTM 172

Query: 120 IAELVGLPVVNASMYDWGTAMAEAALMTVRLHRGKRKKFIVPRHTHPERLQVLETYAKGP 179
           + ++ G+ V NAS+ D GTA AEA  +  R  + KR+KF +    HP+      T A   
Sbjct: 173 VCDITGMDVANASLLDEGTAAAEAMQLCHR--QNKRRKFYIDARCHPQ------TIANYT 224

Query: 180 GVEIETVKWNERGQVDIEDLKEKVKDAAGVYVEIPNFFGLLEEEVREIGEIAHEAGAYFV 239
           GV  E    +E        +    KD +GV  + P+  G +E+   E+ E AH+ G    
Sbjct: 225 GVITELKLPHE--------MDFSGKDVSGVLFQYPDTEGKVED-FSELIERAHQNGTLAC 275

Query: 240 VGVDPTILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPGRLI 299
              D   L I++ PGE G D+V+G +  FG P+ +GGP A  FAV+ +  L+R MPGR++
Sbjct: 276 CATDLLALCILKPPGEFGVDVVLGSSQRFGVPLCYGGPHAAFFAVKEN--LVRMMPGRMV 333

Query: 300 GMTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRGIRELGE 359
           G+T+DA GK  + + LQTREQHIRR KATSNIC+ +AL+A  AA++    G  G++++  
Sbjct: 334 GVTRDANGKEVYRLALQTREQHIRRDKATSNICTAQALLANMAAMYGVYHGSDGLKDIAR 393

Query: 360 VILKNTAYLKKRLSEVAEIPFDGVNFKDVLVRFEKPYKEIHEELLKRNIHGGYY 413
            +   T  L + L          + F  + V      KE+ +    R I+   Y
Sbjct: 394 RVHNATLILAEGLRRAGHKLHHDLFFDTLTVTCGCSVKEVLDRAALRKINVRIY 447


>pir||C82687 glycine decarboxylase XF1385 [imported] - Xylella fastidiosa
           (strain 9a5c) >gi|9106393|gb|AAF84194.1|AE003970_1
           (AE003970) glycine decarboxylase [Xylella fastidiosa]
           Length = 993
           
 Score =  224 bits (565), Expect = 2e-57
 Identities = 133/355 (37%), Positives = 198/355 (55%), Gaps = 19/355 (5%)

Query: 3   KHYIPNSAHKEEMLKEIGLSSIDELFADIPGKFIRDE--LNLPEGKSEYEVFLEMNEILG 60
           +H  PN     +ML+ +G  S++ L   I  + IR    L+LP+G +E E   ++  I  
Sbjct: 33  RHIGPNDVEIAQMLRVVGYDSLESLTDAIVPEKIRSTVALDLPKGITEEEALAKIRVIAN 92

Query: 61  KNKTVLEMPTFLGAGTYFHYIPAHV-KYLIERSEFLTAYTPYQPEISQGMLQALFEYQSL 119
           KN+      +F+G G Y  + P  + + ++E   + TAYTPYQ EISQG ++AL  +Q++
Sbjct: 93  KNRV---FRSFIGQGYYGTHTPKVILRNVLENPAWYTAYTPYQAEISQGRMEALINFQTM 149

Query: 120 IAELVGLPVVNASMYDWGTAMAEAALMTVRLHRGKRKKFIVPRHTHPERLQVLETYAKGP 179
            A+L G+ + NAS+ D  TA AEA  +  R  + +   F V    HP+ L++L T A+  
Sbjct: 150 CADLTGMEIANASLLDEATAAAEAMSLAKRSAKSRSDLFFVHDAVHPQTLELLRTRAEPL 209

Query: 180 GVEIETVKWNERGQVDIEDLKEKVKDAAGVYVEIPNFFGLLEEEVREIGEIAHEAGAYFV 239
           G+ +      E  Q D+           G+ ++ P+ FG + +  R + +  H  G    
Sbjct: 210 GIVLRVGTPEEALQADV----------FGILLQYPDTFGRIGDH-RVLADAVHARGGLVA 258

Query: 240 VGVDPTILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPGRLI 299
           V  D   L ++  PGE GADIVVG +  FG P  FGGP AG  A R+  K  R +PGRLI
Sbjct: 259 VASDLLALTLITPPGEWGADIVVGNSQRFGVPFGFGGPHAGFMACRDIYK--RSIPGRLI 316

Query: 300 GMTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRGI 354
           G++ DA G  A+ + LQTREQHIRR KATSNIC+ + L+AV A+++    GP+G+
Sbjct: 317 GVSVDAAGHPAYRLALQTREQHIRREKATSNICTAQVLLAVMASMYAVYHGPQGL 371


 Score = 77.6 bits (188), Expect = 3e-13
 Identities = 89/371 (23%), Positives = 162/371 (42%), Gaps = 41/371 (11%)

Query: 100 PYQPEIS-QGMLQALFEYQSLIAELVGLPVVNASMYDWGTAMAEAALMTVRLH---RGKR 155
           P  P +   G  Q + E ++++AE  G   ++      G     A L+ +R +   RG+ 
Sbjct: 542 PLAPAVQWSGYRQLIDELEAMLAECTGYDAISLQPNS-GAQGEYAGLLAIRAYHRSRGEE 600

Query: 156 KKFI--VPRHTHPERLQVLETYAKGPGVEIETVKWNERGQVDIEDLK---EKVKDA-AGV 209
           ++ +  +P   H          A+  G+++  +K +  G VD++DL+   EK  D+ A +
Sbjct: 601 RRNVCLIPESAHGTN----PASAQLCGMQVVIIKCDRSGNVDVDDLRMKAEKYSDSLAAL 656

Query: 210 YVEIPNFFGLLEEEVREIGEIAH-EAGAYFVVGVDPTILGIVEAPGELGADIV-VGEASY 267
            V  P+  G+ EE + EI EI H   G  +  G +   L  V  PG  G+D+  +     
Sbjct: 657 MVTYPSTHGVFEEAITEICEIVHAHGGQVYTDGANMNALVGVAKPGRWGSDVSHLNLHKT 716

Query: 268 FGNPMNFGGPRAGIFAVRNDMKLIRQMPGRLIGMTKDAEGKRAFVMTLQTREQHIRRAKA 327
           F  P   GGP  G  AV+  +          +  T    G  A +    T+E  +    A
Sbjct: 717 FCIPHGGGGPGVGPCAVKAHL-------APFLPKTLPLPGDAAGLPVQGTQEAKVGMVSA 769

Query: 328 TSNICSNEALVAVAAAIHIASLGPRGIRELGEVILKNTAYLKKRLSEVAEIPFDGVNFKD 387
            +      A +   + ++I  +G  G+R+  +V L N  Y+ KRL+   +  + G   + 
Sbjct: 770 AN---FGSASILPVSWMYITMMGAAGLRKATQVALLNANYIAKRLAPHYKTLYTG---RH 823

Query: 388 VLVRFE-----KPYKEIH----EELLKRNIHGGYYVGK-HFPELGESALFAATETTRKEW 437
            LV  E     +P +++     E++ KR I  G++     FP  G + +   TE+  ++ 
Sbjct: 824 GLVAHECILDVRPLEKVSGVSAEDIAKRLIDFGFHAPTLSFPVAG-TLMVEPTESESQQE 882

Query: 438 VDALISALREV 448
           +D  + A+ ++
Sbjct: 883 LDRFVDAMIQI 893


>pir||S70896 aminomethyltransferase (EC 2.1.2.10) - yeast (Saccharomyces
           cerevisiae)
           Length = 1034
           
 Score =  223 bits (562), Expect = 4e-57
 Identities = 137/378 (36%), Positives = 215/378 (56%), Gaps = 23/378 (6%)

Query: 3   KHYIPNSAHKEEMLKEIGLSSIDELFADI--PGKFIRDELNLPEGKSEY--EVFLEMNEI 58
           +H  P+ +  ++MLK +G S ++    ++  P    R  L L      +  +V L+  E 
Sbjct: 70  RHLGPSPSVVKKMLKTMGYSDLNAFIEELVPPNILKRRPLKLEAPSKGFCEQVSLQHLEK 129

Query: 59  LGKNKTVLEMPTFLGAGTYFHYIPAHV-KYLIERSEFLTAYTPYQPEISQGMLQALFEYQ 117
           +  NK   ++  F+G G Y   +P  + + L+E  E+ T+YTPYQPEISQG L+AL  +Q
Sbjct: 130 IA-NKNHYKVKNFIGKGYYGTILPPVIQRNLLESPEWYTSYTPYQPEISQGRLEALLNFQ 188

Query: 118 SLIAELVGLPVVNASMYDWGTAMAEAALMTVRLHRGKRKKFIVPRHTHPERLQVLETYAK 177
           +++++L GLPV NAS+ D GTA  EA L++  + R K+ K+++ +  H +   VL T A 
Sbjct: 189 TVVSDLTGLPVANASLLDEGTAAGEAMLLSFNISRKKKLKYVIDKKLHQQTKSVLHTRAL 248

Query: 178 GPGVEIETVKWNERGQVDIEDLKEKV-----KDAAGVYVEIPNFFG--LLEEEVREIGEI 230
              +EI         +VD  D+K+ V      D +G  V+ P   G  L  + ++++ + 
Sbjct: 249 PFNIEII--------EVDCSDIKKAVDVLKNPDVSGCLVQYPATDGSILPPDSMKQLSDA 300

Query: 231 AHEAGAYFVVGVDPTILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVRNDMKL 290
            H   +   V  D   L +++ P   GADIV+G +  FG PM +GGP A  FAV +  KL
Sbjct: 301 LHSHKSLLSVASDLMALTLLKPPAHYGADIVLGSSQRFGVPMGYGGPHAAFFAVID--KL 358

Query: 291 IRQMPGRLIGMTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLG 350
            R++PGR++G++KD  GK A  +TLQTREQHI+R KATSNIC+ +AL+A  A+ +    G
Sbjct: 359 NRKIPGRIVGISKDRLGKTALRLTLQTREQHIKRDKATSNICTAQALLANVASSYCVYHG 418

Query: 351 PRGIRELGEVILKNTAYL 368
           P+G++ +   I   T+ L
Sbjct: 419 PKGLQNISRRIFSLTSIL 436


>sp|Q50601|GCSP_MYCTU PROBABLE GLYCINE DEHYDROGENASE [DECARBOXYLATING] (GLYCINE
           DECARBOXYLASE) (GLYCINE CLEAVAGE SYSTEM P-PROTEIN)
           >gi|7478080|pir||A70722 probable gcvB protein -
           Mycobacterium tuberculosis (strain H37RV)
           >gi|1483539|emb|CAB01470.1| (Z78020) gcvB [Mycobacterium
           tuberculosis]
           Length = 941
           
 Score =  222 bits (559), Expect = 8e-57
 Identities = 140/353 (39%), Positives = 191/353 (53%), Gaps = 30/353 (8%)

Query: 15  MLKEIGLSSIDELFADIPGKFIRDEL----------NLPEGKSEYEVFLEMNEILGKNKT 64
           ML  IG+ S+D+L        I D L          +LP   SE E   E+  +   N  
Sbjct: 22  MLAVIGVDSLDDLAVKAVPAGILDTLTDTGAAPGLDSLPPAASEAEALAELRALADANTV 81

Query: 65  VLEMPTFLGAGTY-FHYIPAHVKYLIERSEFLTAYTPYQPEISQGMLQALFEYQSLIAEL 123
            + M   +G G Y  H  P  ++ +IE   + TAYTPYQPEISQG L+AL  +Q+L+ +L
Sbjct: 82  AVSM---IGQGYYDTHTPPVLLRNIIENPAWYTAYTPYQPEISQGRLEALLNFQTLVTDL 138

Query: 124 VGLPVVNASMYDWGTAMAEAALMTVRLHRGKRKKFIVPRHTHPERLQVLETYAKGPGVEI 183
            GL + NASM D GTA AEA  +  R  RG  K+ +V      +   VL T AK  G+EI
Sbjct: 139 TGLEIANASMLDEGTAAAEAMTLMHRAARGPVKRVVVDADVFTQTAAVLATRAKPLGIEI 198

Query: 184 ETVKWNERGQVDIEDLKEKVKDAA--GVYVEIPNFFGLLEEEVREIGEIAHEAGAYFVVG 241
            T            DL+  + D    GV  ++P   G + +    + + AH+ GA   VG
Sbjct: 199 VTA-----------DLRAGLPDGEFFGVIAQLPGASGRITDWSALVQQ-AHDRGALVAVG 246

Query: 242 VDPTILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPGRLIGM 301
            D   L ++  PGE+GAD+  G    FG PM FGGP AG  AV    K  RQ+PGRL+G+
Sbjct: 247 ADLLALTLIAPPGEIGADVAFGTTQRFGVPMGFGGPHAGYLAVH--AKHARQLPGRLVGV 304

Query: 302 TKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRGI 354
           + D++G  A+ + LQTREQHIRR KATSNIC+ + L+AV AA++ +  G  G+
Sbjct: 305 SVDSDGTPAYRLALQTREQHIRRDKATSNICTAQVLLAVLAAMYASYHGAGGL 357


>gb|AAF54512.1| (AE003686) CG3999 gene product [Drosophila melanogaster]
           Length = 985
           
 Score =  219 bits (553), Expect = 4e-56
 Identities = 131/363 (36%), Positives = 207/363 (56%), Gaps = 19/363 (5%)

Query: 2   AKHYIPNSAHKEEMLKEIGLSSIDELFAD-IPGKF-IRDELNLPEGKSEYEVFLEMNEIL 59
           ++H  P       ML  +G  S+ EL    +P    ++ EL+L +  +E+E+   + +I 
Sbjct: 39  SRHIGPRKTDVVAMLDTLGFKSLAELTEKAVPQSIQLKRELDLDKPLNEHELIRRIRDIS 98

Query: 60  GKNKTVLEMPTFLGAGTYFHYIP-AHVKYLIERSEFLTAYTPYQPEISQGMLQALFEYQS 118
            KN+      +++G G +  ++P   ++ + E   + T YTPYQPEI+QG L++L  YQ+
Sbjct: 99  LKNQL---WRSYIGMGYHNCHVPHTIIRNMFENPGWTTQYTPYQPEIAQGRLESLLNYQT 155

Query: 119 LIAELVGLPVVNASMYDWGTAMAEAALMTVRLHRGKRKKFIVPRHTHPERLQVLETYAKG 178
           L+ +L GL V NAS+ D GTA AEA  +  R    KRKK  +    HP+ L V++T  + 
Sbjct: 156 LVTDLTGLDVANASLLDEGTAAAEAMCLATR--HNKRKKLYLSNRVHPQTLSVVKTRTEA 213

Query: 179 PGVEIETVKWNERGQVDIEDLKEKVKDAAGVYVEIPNFFGLLEEEVREIGEIAHEAGAYF 238
             +EI        G ++  DL  +  + AG+ ++ P+ +G +++   +I  +A + G   
Sbjct: 214 LELEIVV------GPIEQADLPSR--ELAGILLQYPDTYGDVKD-FEDIAALAKKNGTLV 264

Query: 239 VVGVDPTILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPGRL 298
           VV  D   L ++  P E GADI VG +   G P+ +GGP AG FA +    L+R MPGR+
Sbjct: 265 VVATDLLSLTLLRPPAEFGADIAVGTSQRLGVPLGYGGPHAGFFACKQS--LVRLMPGRM 322

Query: 299 IGMTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRGIRELG 358
           IG+T+D +G  A+ + LQTREQHIRR KATSNIC+ +AL+A  +A++    GP G++ + 
Sbjct: 323 IGVTRDMDGNDAYRLALQTREQHIRRDKATSNICTAQALLANMSAMYAIYHGPEGLKAMA 382

Query: 359 EVI 361
             I
Sbjct: 383 NRI 385


>pir||T46636 glycine dehydrogenase (decarboxylating) (EC 1.4.4.2) [imported] -
           Hordeum sp. x Triticum sp >gi|2565305|gb|AAB82711.1|
           (AF024589) glycine decarboxylase P subunit [Hordeum x
           Triticum]
           Length = 1031
           
 Score =  217 bits (547), Expect = 2e-55
 Identities = 141/392 (35%), Positives = 208/392 (52%), Gaps = 31/392 (7%)

Query: 3   KHYIPNSAHKEEMLKEIGLSSIDELF-ADIPGKFIRDELNLP----EGKSEYEVFLEMNE 57
           +H     A +  M  E G +++D L  A +P       +        G +E ++   M  
Sbjct: 73  RHNSATPAEQAVMASECGFNTLDALIDATVPAAIRAPPMQFTGKFDAGFTESQMLEHMAH 132

Query: 58  ILGKNKTVLEMPTFLGAGTYFHYIPAHV-KYLIERSEFLTAYTPYQPEISQGMLQALFEY 116
           +   NKT     +F+G G Y  +IPA + + L+E   + T YTPYQ EI+QG L++L  Y
Sbjct: 133 LASMNKTY---KSFIGMGYYNTHIPAVILRNLMENPAWYTQYTPYQAEIAQGRLESLLNY 189

Query: 117 QSLIAELVGLPVVNASMYDWGTAMAEAALMTVRLHRGKRKKFIVPRHTHPERLQVLETYA 176
           Q+++A+L GLP+ NAS+ D  TA AEA  M + + + K+K F++  + HP+ + + +T A
Sbjct: 190 QTMVADLTGLPMSNASLLDEATAAAEAMAMCLGIVKSKKKTFLIASNCHPQTIDICQTRA 249

Query: 177 KGPGVEIETVKWNERGQVDIEDLKEKVKDAAGVYVEIPNFFGLLEEEVREIGEI---AHE 233
            G  + +             +D      D  GV V+ P      E EV +  E    AH 
Sbjct: 250 TGFDINVVVSA--------AKDFDYSSGDVCGVLVQYPG----TEGEVLDYAEFVKDAHA 297

Query: 234 AGAYFVVGVDPTILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQ 293
            G   V+  D   L  +  PGE+GADI VG A  FG PM +GGP A   A   + K  R 
Sbjct: 298 HGVKVVMATDLLALTTLRPPGEIGADIAVGSAQRFGVPMGYGGPHAAFLATSQEYK--RL 355

Query: 294 MPGRLIGMTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRG 353
           MPGR+IG++ D+ GK A  M +QTREQHIRR KATSNIC+ +AL+A  AA++    GP G
Sbjct: 356 MPGRIIGVSVDSSGKPALRMAMQTREQHIRRDKATSNICTAQALLANMAAMYAVYHGPAG 415

Query: 354 IRELGEVI--LKNT-AYLKKRLSEVA--EIPF 380
           ++ + + +  L  T A+  K+L  V   E+P+
Sbjct: 416 LKAIADRVHGLAGTFAHGLKKLGTVTVQELPY 447


>gb|AAA63798.1| (U11693) victorin binding protein [Avena sativa]
           Length = 1032
           
 Score =  215 bits (541), Expect = 1e-54
 Identities = 140/392 (35%), Positives = 208/392 (52%), Gaps = 31/392 (7%)

Query: 3   KHYIPNSAHKEEMLKEIGLSSIDELF-ADIPGKFIRDELNLP----EGKSEYEVFLEMNE 57
           +H   + A +  M    G +++D L  A +P       +        G +E ++   M  
Sbjct: 74  RHNSASPAEQTVMASTCGFNTLDSLIDATVPAAIRAPPMQFTGKFDAGFTESQMLEHMAH 133

Query: 58  ILGKNKTVLEMPTFLGAGTYFHYIPAHV-KYLIERSEFLTAYTPYQPEISQGMLQALFEY 116
           +   NK      +F+G G Y  +IPA + + L+E   + T YTPYQ EI+QG L++L  Y
Sbjct: 134 LASMNKVY---KSFIGMGYYNTHIPAVILRNLMENPAWYTQYTPYQAEIAQGRLESLLNY 190

Query: 117 QSLIAELVGLPVVNASMYDWGTAMAEAALMTVRLHRGKRKKFIVPRHTHPERLQVLETYA 176
           Q+++A+L GLP+ NAS+ D  TA AEA  M   + + K+K F++  + HP+ + + +T A
Sbjct: 191 QTMVADLTGLPMSNASLLDEATAAAEAMAMCNGILKAKKKTFLIASNCHPQTIDICQTRA 250

Query: 177 KGPGVEIETVKWNERGQVDIEDLKEKVKDAAGVYVEIPNFFGLLEEEVREIGEI---AHE 233
            G  + +           D +D      D  GV V+ P      E EV +  E    AH+
Sbjct: 251 AGFDLNVVV--------SDAKDFDYSSGDVCGVLVQYPG----TEGEVLDYAEFVKDAHK 298

Query: 234 AGAYFVVGVDPTILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQ 293
            G   V+  D   L  +  PGE+GADI VG A  FG PM +GGP A   A   + K  R 
Sbjct: 299 HGVKVVMATDLLALTTLRPPGEIGADIAVGSAQRFGVPMGYGGPHAAFLATSQEYK--RL 356

Query: 294 MPGRLIGMTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRG 353
           MPGR+IG++ D+ GK A  M +QTREQHIRR KATSNIC+ +AL+A  AA++    GP G
Sbjct: 357 MPGRIIGVSVDSSGKPALRMAMQTREQHIRRDKATSNICTAQALLANMAAMYAVYHGPAG 416

Query: 354 IRELGEVI--LKNT-AYLKKRLSEVA--EIPF 380
           ++ + + +  L  T A+  K+L  V   E+P+
Sbjct: 417 LKAIADRVHGLAGTFAHGLKKLGTVTVQELPY 448


>pir||S76257 hypothetical protein - Synechocystis sp. (strain PCC 6803)
           >gi|1653603|dbj|BAA18516.1| (D90914) P protein of
           glycine cleavage complex [Synechocystis sp.]
           Length = 983
           
 Score =  213 bits (537), Expect = 3e-54
 Identities = 127/369 (34%), Positives = 199/369 (53%), Gaps = 18/369 (4%)

Query: 3   KHYIPNSAHKEEMLKEIGLSSIDELFADIPGKFIR--DELNLPEGKSEYEVFLEMNEILG 60
           +H  P    + +ML+ +G  ++ +L        IR    L LP  +SEY    ++  I  
Sbjct: 36  RHLGPGETEQRQMLQTLGFDTLGDLIDQAVPPAIRFPRSLQLPASQSEYGAIAQLKSIAS 95

Query: 61  KNKTVLEMPTFLGAGTYFHYIPAHV-KYLIERSEFLTAYTPYQPEISQGMLQALFEYQSL 119
           KN+      +++G G Y    P  + + ++E   + TAYTPYQ EI+QG L+AL  +Q++
Sbjct: 96  KNQV---FRSYIGMGYYDTITPPVIQRNILENPGWYTAYTPYQAEIAQGRLEALLNFQTM 152

Query: 120 IAELVGLPVVNASMYDWGTAMAEAALMTVRLHRGKRKKFIVPRHTHPERLQVLETYAKGP 179
           + +L GL + NAS+ D GTA AEA  ++  + + K   F V +  HP+ ++V++T A   
Sbjct: 153 VMDLTGLEIANASLLDEGTAAAEAMALSYGVSKSKANAFFVAQDCHPQTIEVIKTRANPL 212

Query: 180 GVEIETVKWNERGQVDIEDLKEKVKDAAGVYVEIPNFFGLLEEEVREIGEIAHEAGAYFV 239
           G+E+        G          +    G  ++ P   G +  + R   + AH+  A   
Sbjct: 213 GIEVIV------GDHHTFSFSTSI---FGALLQYPATDGAV-YDYRSFIDKAHQHQALVT 262

Query: 240 VGVDPTILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPGRLI 299
           +  DP  L ++  PGELGADI VG    FG P+ +GGP A  FA + + +  R+MPGR++
Sbjct: 263 LAADPLSLTLLTPPGELGADIAVGSTQRFGIPLGYGGPHAAYFATKAEYQ--RKMPGRIV 320

Query: 300 GMTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRGIRELGE 359
           G++KDA G  A  + LQTREQHIRR KATSNIC+ + L+AV A+++    G  G++ +  
Sbjct: 321 GVSKDAHGNPALRLALQTREQHIRRDKATSNICTAQVLLAVMASMYGVYHGSTGLKNIAL 380

Query: 360 VILKNTAYL 368
            I + T  L
Sbjct: 381 RIHQLTVLL 389


>sp|P33195|GCSP_ECOLI GLYCINE DEHYDROGENASE [DECARBOXYLATING] (GLYCINE DECARBOXYLASE)
           (GLYCINE CLEAVAGE SYSTEM P-PROTEIN)
           >gi|480419|pir||S36834 glycine dehydrogenase
           (decarboxylating) (EC 1.4.4.2) - Escherichia coli
           >gi|304892|gb|AAA23867.1| (L20872) gcvHP [Escherichia
           coli] >gi|403345|emb|CAA52146.1| (X73958) glycine
           dehydrogenase (decarboxylating) [Escherichia coli]
           >gi|1789269|gb|AAC75941.1| (AE000373) glycine
           decarboxylase, P protein of glycine cleavage system
           [Escherichia coli K12]
           Length = 957
           
 Score =  212 bits (534), Expect = 7e-54
 Identities = 143/388 (36%), Positives = 208/388 (52%), Gaps = 43/388 (11%)

Query: 3   KHYIPNSAHKEEMLKEIGLSSIDELFADIPGKFIR----DELNLPEGKSEYEVFLEMNEI 58
           +H  P++A ++EML  +G  S++ L   I  K I+     ++  P   +EY    E+  I
Sbjct: 17  RHIGPDAAQQQEMLNAVGAQSLNALTGQIVPKDIQLATPPQVGAPA--TEYAALAELKAI 74

Query: 59  LGKNKTVLEMPTFLGAG-TYFHYIPAHVKYLIERSEFLTAYTPYQPEISQGMLQALFEYQ 117
             +NK      +++G G T     P  ++ ++E   + TAYTPYQPE+SQG L+AL  +Q
Sbjct: 75  ASRNK---RFTSYIGMGYTAVQLPPVILRNMLENPGWYTAYTPYQPEVSQGRLEALLNFQ 131

Query: 118 SLIAELVGLPVVNASMYDWGTAMAEAALMTVRLHRGKR-KKFIVPRHTHPERLQVLETYA 176
            +  +L GL + +AS+ D  TA AEA  M  R+ + K   +F V    HP+ L V+ T A
Sbjct: 132 QVTLDLTGLDMASASLLDEATAAAEAMAMAKRVSKLKNANRFFVASDVHPQTLDVVRTRA 191

Query: 177 KGPGVEIETVKWNERGQVDIEDLKEKVKDAAGVYVEIPNFFGLLEEEVREIGEIAHEAGA 236
           +  G E+            I D  +KV D   V       FG+L ++V   GEI H+  A
Sbjct: 192 ETFGFEV------------IVDDAQKVLDHQDV-------FGVLLQQVGTTGEI-HDYTA 231

Query: 237 YF--------VVGVDPTILGIV--EAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVRN 286
                     VV V   I+ +V   APG+ GADIV G A  FG PM +GGP A  FA ++
Sbjct: 232 LISELKSRKIVVSVAADIMALVLLTAPGKQGADIVFGSAQRFGVPMGYGGPHAAFFAAKD 291

Query: 287 DMKLIRQMPGRLIGMTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHI 346
           + K  R MPGR+IG++KDA G  A  M +QTREQHIRR KA SNIC+++ L+A  A+++ 
Sbjct: 292 EYK--RSMPGRIIGVSKDAAGNTALRMAMQTREQHIRREKANSNICTSQVLLANIASLYA 349

Query: 347 ASLGPRGIRELGEVILKNTAYLKKRLSE 374
              GP G++ +   I + T  L   L +
Sbjct: 350 VYHGPVGLKRIANRIHRLTDILAAGLQQ 377


 Score = 71.4 bits (172), Expect = 2e-11
 Identities = 87/374 (23%), Positives = 153/374 (40%), Gaps = 48/374 (12%)

Query: 93  EFLTAYTPYQPEISQGMLQALFEYQSLIAELVGLPVVNASMYDWGTAMAEAALMTVRLHR 152
           EF   +    PE ++G  Q + +    + +L G   V     + G     A L+ +R + 
Sbjct: 529 EFAELHPFCPPEQAEGYQQMIAQLADWLVKLTGYDAV-CMQPNSGAQGEYAGLLAIRHYH 587

Query: 153 -----GKRKKFIVPRHTHPERLQVLETYAKGPGVEIETVKWNERGQVDIEDLKEKVKDAA 207
                G R   ++P   H          A   G+++  V  ++ G +D+ DL+ K + A 
Sbjct: 588 ESRNEGHRDICLIPASAHGTN----PASAHMAGMQVVVVACDKNGNIDLTDLRAKAEQAG 643

Query: 208 G----VYVEIPNFFGLLEEEVREIGEIAHE-AGAYFVVGVDPTILGIVEAPGELGADIV- 261
                + V  P+  G+ EE +RE+ E+ H+  G  ++ G +      + +PG +GAD+  
Sbjct: 644 DNLSCIMVTYPSTHGVYEETIREVCEVVHQFGGQVYLDGANMNAQVGITSPGFIGADVSH 703

Query: 262 VGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPGRLIGMTKDAEGKRAFVMTLQTREQH 321
           +     F  P   GGP  G   V+    L   +PG  +                   E  
Sbjct: 704 LNLHKTFCIPHGGGGPGMGPIGVK--AHLAPFVPGHSVVQI----------------EGM 745

Query: 322 IRRAKATSNICSNEALVAVAAAIHIASLGPRGIRELGEVILKNTAYLKKRLSEVAEIPFD 381
           + R  A S      A +   + ++I  +G  G+++  +V + N  Y+  RL +   + + 
Sbjct: 746 LTRQGAVSAAPFGSASILPISWMYIRMMGAEGLKKASQVAILNANYIASRLQDAFPVLYT 805

Query: 382 GVNFKDVLVRFE-----KPYKE---IHE-ELLKRNIHGGYYV-GKHFPELGESALFAATE 431
           G   +D  V  E     +P KE   I E ++ KR I  G++     FP  G + +   TE
Sbjct: 806 G---RDGRVAHECILDIRPLKEETGISELDIAKRLIDYGFHAPTMSFPVAG-TLMVEPTE 861

Query: 432 TTRKEWVDALISAL 445
           +  K  +D  I A+
Sbjct: 862 SESKVELDRFIDAM 875


>gb|AAA69071.1| (U28377) ORF_f957 [Escherichia coli]
           Length = 957
           
 Score =  212 bits (534), Expect = 7e-54
 Identities = 143/388 (36%), Positives = 208/388 (52%), Gaps = 43/388 (11%)

Query: 3   KHYIPNSAHKEEMLKEIGLSSIDELFADIPGKFIR----DELNLPEGKSEYEVFLEMNEI 58
           +H  P++A ++EML  +G  S++ L   I  K I+     ++  P   +EY    E+  I
Sbjct: 17  RHIGPDAAQQQEMLNAVGAQSLNALTGQIVPKDIQLATPPQVGAPA--TEYAALAELKAI 74

Query: 59  LGKNKTVLEMPTFLGAG-TYFHYIPAHVKYLIERSEFLTAYTPYQPEISQGMLQALFEYQ 117
             +NK      +++G G T     P  ++ ++E   + TAYTPYQPE+SQG L+AL  +Q
Sbjct: 75  ASRNK---RFTSYIGMGYTAVQLPPVILRNMLENPGWYTAYTPYQPEVSQGRLEALLNFQ 131

Query: 118 SLIAELVGLPVVNASMYDWGTAMAEAALMTVRLHRGKR-KKFIVPRHTHPERLQVLETYA 176
            +  +L GL + +AS+ D  TA AEA  M  R+ + K   +F V    HP+ L V+ T A
Sbjct: 132 QVTLDLTGLDMASASLLDEATAAAEAMAMAKRVXKLKNANRFFVASDVHPQTLDVVRTRA 191

Query: 177 KGPGVEIETVKWNERGQVDIEDLKEKVKDAAGVYVEIPNFFGLLEEEVREIGEIAHEAGA 236
           +  G E+            I D  +KV D   V       FG+L ++V   GEI H+  A
Sbjct: 192 ETFGFEV------------IVDDAQKVLDHQDV-------FGVLLQQVGTTGEI-HDYTA 231

Query: 237 YF--------VVGVDPTILGIV--EAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVRN 286
                     VV V   I+ +V   APG+ GADIV G A  FG PM +GGP A  FA ++
Sbjct: 232 LISELKSRKIVVSVAADIMALVLLTAPGKQGADIVFGSAQRFGVPMGYGGPHAAFFAAKD 291

Query: 287 DMKLIRQMPGRLIGMTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHI 346
           + K  R MPGR+IG++KDA G  A  M +QTREQHIRR KA SNIC+++ L+A  A+++ 
Sbjct: 292 EYK--RSMPGRIIGVSKDAAGNTALRMAMQTREQHIRREKANSNICTSQVLLANIASLYA 349

Query: 347 ASLGPRGIRELGEVILKNTAYLKKRLSE 374
              GP G++ +   I + T  L   L +
Sbjct: 350 VYHGPVGLKRIANRIHRLTDILAAGLQQ 377


 Score = 71.4 bits (172), Expect = 2e-11
 Identities = 87/374 (23%), Positives = 153/374 (40%), Gaps = 48/374 (12%)

Query: 93  EFLTAYTPYQPEISQGMLQALFEYQSLIAELVGLPVVNASMYDWGTAMAEAALMTVRLHR 152
           EF   +    PE ++G  Q + +    + +L G   V     + G     A L+ +R + 
Sbjct: 529 EFAELHPFCPPEQAEGYQQMIAQLADWLVKLTGYDAV-CMQPNSGAQGEYAGLLAIRHYH 587

Query: 153 -----GKRKKFIVPRHTHPERLQVLETYAKGPGVEIETVKWNERGQVDIEDLKEKVKDAA 207
                G R   ++P   H          A   G+++  V  ++ G +D+ DL+ K + A 
Sbjct: 588 ESRNEGHRDICLIPASAHGTN----PASAHMAGMQVVVVACDKNGNIDLTDLRAKAEQAG 643

Query: 208 G----VYVEIPNFFGLLEEEVREIGEIAHE-AGAYFVVGVDPTILGIVEAPGELGADIV- 261
                + V  P+  G+ EE +RE+ E+ H+  G  ++ G +      + +PG +GAD+  
Sbjct: 644 DNLSCIMVTYPSTHGVYEETIREVCEVVHQFGGQVYLDGANMNAQVGITSPGFIGADVSH 703

Query: 262 VGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPGRLIGMTKDAEGKRAFVMTLQTREQH 321
           +     F  P   GGP  G   V+    L   +PG  +                   E  
Sbjct: 704 LNLHKTFCIPHGGGGPGMGPIGVK--AHLAPFVPGHSVVQI----------------EGM 745

Query: 322 IRRAKATSNICSNEALVAVAAAIHIASLGPRGIRELGEVILKNTAYLKKRLSEVAEIPFD 381
           + R  A S      A +   + ++I  +G  G+++  +V + N  Y+  RL +   + + 
Sbjct: 746 LTRQGAVSAAPFGSASILPISWMYIRMMGAEGLKKASQVAILNANYIASRLQDAFPVLYT 805

Query: 382 GVNFKDVLVRFE-----KPYKE---IHE-ELLKRNIHGGYYV-GKHFPELGESALFAATE 431
           G   +D  V  E     +P KE   I E ++ KR I  G++     FP  G + +   TE
Sbjct: 806 G---RDGRVAHECILDIRPLKEETGISELDIAKRLIDYGFHAPTMSFPVAG-TLMVEPTE 861

Query: 432 TTRKEWVDALISAL 445
           +  K  +D  I A+
Sbjct: 862 SESKVELDRFIDAM 875


>pir||E82994 glycine cleavage system protein P1 PA5213 [imported] - Pseudomonas
           aeruginosa (strain PAO1)
           >gi|9951520|gb|AAG08598.1|AE004934_5 (AE004934) glycine
           cleavage system protein P1 [Pseudomonas aeruginosa]
           Length = 958
           
 Score =  209 bits (527), Expect = 5e-53
 Identities = 132/371 (35%), Positives = 196/371 (52%), Gaps = 19/371 (5%)

Query: 1   MAKHYIPNSAHKEEMLKEIGLSSIDELFADI--PGKFIRDELNLPEGKSEYEVFLEMNEI 58
           + +H  P+ A ++ ML  +G+S+  EL      P   +   L LP    E      +   
Sbjct: 17  LRRHLGPDPAEQQAMLAFLGVSTRAELIVQTVPPAIRLNRPLELPAALDEQAALARLRGY 76

Query: 59  LGKNKTVLEMPTFLGAGTYFHYIPAHV-KYLIERSEFLTAYTPYQPEISQGMLQALFEYQ 117
            G N+      + +G G Y    P+ + + ++E   + TAYTPYQPEI+QG L+AL  +Q
Sbjct: 77  AGLNQ---RWTSLIGMGYYGTVTPSVILRNVLENPGWYTAYTPYQPEIAQGRLEALLNFQ 133

Query: 118 SLIAELVGLPVVNASMYDWGTAMAEAALMTVRLHRGKRKKFIVPRHTHPERLQVLETYAK 177
            L  +L GL + +AS+ D  TA AEA  +  R+ + +  +F V  H HP+ + VL T A+
Sbjct: 134 QLTIDLTGLDLASASLLDEATAAAEAMALARRVAKARSNRFFVDAHCHPQTVSVLRTRAE 193

Query: 178 GPGVEIETVKWNERGQVDIEDLKEKVKDAAGVYVEIPNFFGLLEEEVREIGEIAHEAGAY 237
             G E+          VD  D         G  ++ P+  G +  ++R + E  H   A 
Sbjct: 194 AFGFEL---------VVDEPD-NLAAHAVFGALLQYPDSRGEI-RDLRPLIEALHGQQAL 242

Query: 238 FVVGVDPTILGIVEAPGELGADIVVGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPGR 297
             V  D   L ++  PGELGAD+V+G A  FG PM +GGP A  FA R   K  R MPGR
Sbjct: 243 ACVASDLLALLLLTPPGELGADVVLGSAQRFGVPMGYGGPHAAFFATREGYK--RAMPGR 300

Query: 298 LIGMTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRGIREL 357
           +IG+++DA G  A  M LQTREQHIRR KA SNIC+ + L+A  A+++    GP+ ++ +
Sbjct: 301 IIGVSRDARGNPALRMALQTREQHIRREKANSNICTAQVLLANIASLYAVYHGPQELKRI 360

Query: 358 GEVILKNTAYL 368
            + + + TA L
Sbjct: 361 AQRVQRLTALL 371


>pir||D81821 glycine dehydrogenase (decarboxylating) (EC 1.4.4.2) NMA1934
           [imported] - Neisseria meningitidis (group A strain
           Z2491) >gi|7380566|emb|CAB85154.1| (AL162757) glycine
           dehydrogenase [Neisseria meningitidis Z2491]
           Length = 950
           
 Score =  203 bits (510), Expect = 5e-51
 Identities = 124/350 (35%), Positives = 190/350 (53%), Gaps = 19/350 (5%)

Query: 15  MLKEIGLSSIDELFADIPGKFIR--DELNLPEGKSEYEVFLEMNEILGKNKTVLEMPTFL 72
           +L  +   S+DE   +   + IR   EL+LPE  +E +   ++  I  KN   +   +++
Sbjct: 25  LLAAVDEKSMDEFVGNTVPQSIRMPSELDLPEALTEADALAKLKGIASKN---MINKSYI 81

Query: 73  GAGTYFHYIPAHV-KYLIERSEFLTAYTPYQPEISQGMLQALFEYQSLIAELVGLPVVNA 131
           G G Y   +P  + + ++E   + TAYTPYQ EI+QG L+AL  +Q +  +L G PV  A
Sbjct: 82  GLGYYPTRVPNVILRNVLENPGWYTAYTPYQAEIAQGRLEALLNFQQVCIDLTGFPVAGA 141

Query: 132 SMYDWGTAMAEAALMTVRLHRGKRKKFIVPRHTHPERLQVLETYAKGPGVEIETVKWNER 191
           S+ D  TA AEA  M  R+ + K ++F V    +P+ L V++T AK  G E+    + + 
Sbjct: 142 SLLDEATAAAEAMAMAHRVGKVKSERFFVDERVYPQTLDVMKTRAKYFGFELVVGDFAQA 201

Query: 192 GQVDIEDLKEKVKDAAGVYVEIPNFFGLLEEEVREIGEIAHEAGAYFVVGVDPTILGIVE 251
            + +      +     G   ++ +  G L+ +           G    V  D   L +++
Sbjct: 202 DEGEYFGALFQYVGKDGDVQDLQDVIGRLKAK-----------GTIVAVAADIMSLVLLK 250

Query: 252 APGELGADIVVGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPGRLIGMTKDAEGKRAF 311
           +P ELGADI +G    FG PM FGGP A  FA +++ K  R  PGR+IG++KDA GK A 
Sbjct: 251 SPAELGADIALGNTQRFGVPMGFGGPHAAYFAFKDEFK--RSAPGRIIGVSKDASGKPAL 308

Query: 312 VMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRGIRELGEVI 361
            M L TREQHIRR KATSNIC+ +AL+A  A ++    GP+G++ + + I
Sbjct: 309 RMALSTREQHIRREKATSNICTAQALLANLAGMYAVYHGPKGVKRIADRI 358


>emb|CAA72254.1| (Y11467) putative glycine dehydrogenase (decarboxylating) subunit 1
           [Thermus thermophilus]
           Length = 333
           
 Score =  197 bits (496), Expect = 2e-49
 Identities = 127/324 (39%), Positives = 178/324 (54%), Gaps = 23/324 (7%)

Query: 133 MYDWGTAMAEAALMTVRLHRGKRKKFIVPRHTHPERLQVLETYAKGPGVEIETVKWNERG 192
           MYD  TA+AE  L+ +R     R   +V +  HPE   VL  Y +  G ++ T+   E G
Sbjct: 25  MYDGATALAEGVLLALR--ETGRMGVLVSQGVHPEYRAVLRAYLEAVGAKLLTLPL-EGG 81

Query: 193 QVDIEDLKEKVKDAAGVYVEIPNFFGLLEEEVREIGEIAHEAGAYFVVGVDPTILGIVEA 252
           +  + ++ E+V     V V+ PNF G LE+ +    E AH AGA FV   DP  LG+++ 
Sbjct: 82  RTPLPEVGEEV---GAVVVQNPNFLGALED-LGPFAEAAHGAGALFVAVADPLSLGVLKP 137

Query: 253 PGELGADIVVGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPGRLIGMTKDAEGKRAFV 312
           PG  G DI VG+    G PM FGGP  G  A +     +RQ+PGRL+  T D EG+R F+
Sbjct: 138 PGAYGVDIAVGDGQSLGLPMGFGGPHFGFLATKK--AFVRQLPGRLVSETVDVEGRRGFI 195

Query: 313 MTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRGIRELGEVILKNTAYLKKRL 372
           +TLQ REQ+IRRAKA SNI +N  L A+  A+++A+LGP G+R   EV LK+     K  
Sbjct: 196 LTLQAREQYIRRAKAKSNITTNAQLTALMGAMYLAALGPEGLR---EVALKSVEMAHKLH 252

Query: 373 SEVAEIPFDGVN-------FKDVLVRFEKPYKEIHEELLKRNIHGGYYVGKHFPELGESA 425
           + + E+P  GV        F +  +   K  + +   L +R  HG   V + + E    A
Sbjct: 253 ALLLEVP--GVRPFTPKPFFNEFALALPKDPEAVRRALAERGFHGATPVPREYGE--NLA 308

Query: 426 LFAATETTRKEWVDALISALREVI 449
           LFAATE   +E + AL  AL+EV+
Sbjct: 309 LFAATELHEEEDLLALREALKEVL 332


>dbj|BAB06533.1| (AP001516) glycine dehydrogenase subunit 2 [Bacillus halodurans]
           Length = 488
           
 Score =  115 bits (284), Expect = 1e-24
 Identities = 128/441 (29%), Positives = 201/441 (45%), Gaps = 52/441 (11%)

Query: 31  IPGKFIRDEL-NLPEGKSEYEVFLEMNEILGKNKTVLEMPTFLGAGTYFHYIPAHVKYLI 89
           IP +F+R+E   LPE  SE ++      +  +N  V      LG+ T        +KY  
Sbjct: 36  IPAEFLREEAPELPE-VSELQLMRHYTALSKRNHGVDSGFYPLGSCT--------MKYNP 86

Query: 90  ERSEFLTAYT------PYQPEIS-QGMLQALFEYQSLIAELVGLPVVNASMYDWGTAMAE 142
           + +E +  Y       PYQPE   QG L+ ++E Q+ +AE+ G+  V  ++     A  E
Sbjct: 87  KINEDVARYPGFANIHPYQPEAQVQGALRLMYELQTALAEITGMDEV--TLQPAAGAQGE 144

Query: 143 -AALMTVRLHRG-----KRKKFIVPRHTHPERLQVLETYAKGPGVEIETVKWNERGQVDI 196
              LM +R +        R K IVP   H          A   G E  TV+ +E G VD+
Sbjct: 145 WTGLMLIRAYHEANGDTNRTKVIVPDSAHGTN----PASATVAGFESVTVRTDEDGLVDL 200

Query: 197 EDLKEKV-KDAAGVYVEIPNFFGLLEEEVREIGEIAHEAGA--YFVVGVDPTILGIVEAP 253
           + L+E V +D A + +  PN  GL E  + E+  I HEAG   Y+       ILGI   P
Sbjct: 201 DHLREVVGEDTAALMLTNPNTLGLFEAHIVEMAAIIHEAGGKLYYDGANSNAILGIAR-P 259

Query: 254 GELGADIV-VGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPGRLIGMTKDAEGKRAFV 312
           G++G D+V +     F  P   GGP +G   V+ +  LI  +P  ++   KD +  R   
Sbjct: 260 GDMGFDVVHLNLHKTFTGPHGGGGPGSGPVGVKKE--LIPYLPKPVV--VKDGDSYRLDY 315

Query: 313 MTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRGIRELGEVILKNTAYLKKRL 372
                R   I R K           + V A  +I ++GP G+R + E  + N  Y+ +RL
Sbjct: 316 ----DRPHSIGRVKPYYGNFG----INVRAYTYIRTMGPEGLRTVSEYAVLNANYMMRRL 367

Query: 373 SEVAEIPFDGVNFKDVLVRFEKPYKEIHE---ELLKRNIHGGYYVGK-HFP-ELGESALF 427
           +   ++P+D  + K   V   +  K++     ++ KR +  GY+    +FP  + E  + 
Sbjct: 368 APYFDLPYD-QHCKHEFVLSGRQQKKLGVRTLDIAKRLLDFGYHPPTIYFPLNVEECLMI 426

Query: 428 AATETTRKEWVDALISALREV 448
             TET  KE +D  I A+ ++
Sbjct: 427 EPTETESKETLDEFIEAMIQI 447


>sp|P54377|GCS2_BACSU PROBABLE GLYCINE DEHYDROGENASE [DECARBOXYLATING] SUBUNIT 2 (GLYCINE
           DECARBOXYLASE) (GLYCINE CLEAVAGE SYSTEM P-PROTEIN)
           >gi|7451546|pir||B69959 glycine dehydrogenase homolog
           yqhK - Bacillus subtilis >gi|1303892|dbj|BAA12548.1|
           (D84432) YqhK [Bacillus subtilis]
           >gi|2634889|emb|CAB14386.1| (Z99116) similar to glycine
           dehydrogenase [Bacillus subtilis]
           Length = 488
           
 Score =  112 bits (278), Expect = 7e-24
 Identities = 129/429 (30%), Positives = 195/429 (45%), Gaps = 36/429 (8%)

Query: 35  FIRDE-LNLPEGKSEYEVFLEMNEILGKNKTVLEMPTFLGAGTYFHYIPAHVKYLIERSE 93
           +IRDE   LPE  SE ++      +  +N  V      LG+ T   Y P  +   I R  
Sbjct: 40  YIRDEDAALPE-VSELDIMRHYTALSKRNHGVDSGFYPLGSCT-MKYNPK-INEKIARIP 96

Query: 94  FLTAYTPYQPEIS-QGMLQALFEYQSLIAELVGLPVVNASMYDWGTAMAEAALMTVRLH- 151
              A  P Q E + QG L+ L++    + E+ G+  V       G       LM +R + 
Sbjct: 97  GFAAIHPLQDEDTVQGALELLYDLSKHLEEITGMDEVTLQPAA-GAHGEWTGLMMIRAYH 155

Query: 152 --RG--KRKKFIVPRHTHPERLQVLETYAKGPGVEIETVKWNERGQVDIEDLKEKV-KDA 206
             RG  KR K IVP   H          A   G E  TVK NE+G VD+EDLK  V ++ 
Sbjct: 156 EARGDFKRTKVIVPDSAHGTN----PASATVAGFETVTVKSNEKGLVDLEDLKRAVNEET 211

Query: 207 AGVYVEIPNFFGLLEEEVREIGEIAHEAGA-YFVVGVDPTILGIVEAPGELGADIV-VGE 264
           A + +  PN  GL EE++ E+ EI H+AG   +  G +   +     PG++G D+V +  
Sbjct: 212 AALMLTNPNTLGLFEEQITEMAEIVHQAGGKLYYDGANLNAVLSKARPGDMGFDVVHLNL 271

Query: 265 ASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPGRLIGMTKDAEGKRAFVMTLQTREQHIRR 324
              F  P   GGP +G   V+ D  LI  +P  ++      EG+  F      R   I R
Sbjct: 272 HKTFTGPHGGGGPGSGPVGVKQD--LIPYLPKPVL---VKKEGRFTFDYD---RPHAIGR 323

Query: 325 AKATSNICSNEALVAVAAAIHIASLGPRGIRELGEVILKNTAYLKKRLSEVAEIPFDGVN 384
            K           + V A  +I S+GP G++ + E  + N  Y+ ++L+   ++PFD  +
Sbjct: 324 VKPYYGNFG----INVRAYTYIRSMGPDGLKAVTENAVLNANYMMRKLAPYYDLPFDR-H 378

Query: 385 FKDVLVRFEKPYKEIHE---ELLKRNIHGGYYVGK-HFP-ELGESALFAATETTRKEWVD 439
            K   V   K  K++     ++ KR +  GY+    +FP  + E  +   TET  KE +D
Sbjct: 379 CKHEFVLSGKRQKKLGVRTLDIAKRLLDFGYHPPTIYFPLNVEECIMIEPTETESKETLD 438

Query: 440 ALISALREV 448
           A I A+ ++
Sbjct: 439 AFIDAMIQI 447


>pir||H72403 glycine dehydrogenase (decarboxylating) subunit 2 - Thermotoga
           maritima (strain MSB8)
           >gi|4980712|gb|AAD35306.1|AE001706_5 (AE001706) glycine
           dehydrogenase (decarboxylating) subunit 2 [Thermotoga
           maritima]
           Length = 474
           
 Score =  108 bits (267), Expect = 1e-22
 Identities = 105/366 (28%), Positives = 174/366 (46%), Gaps = 37/366 (10%)

Query: 100 PYQP-EISQGMLQALFEYQSLIAELVGLPVVNASMYDWGTAMAE-AALMTVRLH---RGK 154
           PYQP E  QG L+ ++E + ++ E+ G+   + ++     A  E   ++ VR +   RG 
Sbjct: 93  PYQPVETVQGSLRLMYELKKMLCEITGMD--DMTLQPAAGAHGELTGMLIVREYFKNRGD 150

Query: 155 --RKKFIVPRHTHPERLQVLETYAKGPGVEIETVKWNERGQVDIEDLKEKV-KDAAGVYV 211
             RKK +VP   H          A   G E+  +K ++ G VD+EDLK+ + ++ A V +
Sbjct: 151 TGRKKVLVPDSAHGTN----PASASMVGFEVVEIK-SKNGMVDVEDLKKLLDEEVAAVML 205

Query: 212 EIPNFFGLLEEEVREIGEIAHEAGA--YFVVGVDPTILGIVEAPGELGADIV-VGEASYF 268
             PN  GL E+++ +I E+ HE GA  Y+       I+G V  PG++G DIV +     F
Sbjct: 206 TNPNTLGLFEKDILKIAEMTHECGALLYYDGANLNAIMGKVR-PGDMGFDIVHLNLHKTF 264

Query: 269 GNPMNFGGPRAGIFAVRNDMKLIRQMPGRLIGMTKDAEGKRAFVMTLQTREQHIRRAKAT 328
             P   GGP +G   V+  +      P     + K+ E    FV      E+ I R ++ 
Sbjct: 265 STPHGMGGPGSGPVGVKKHLVDFLPFPQ----VKKNGELYELFVP-----EKTIGRVRSF 315

Query: 329 SNICSNEALVAVAAAIHIASLGPRGIRELGEVILKNTAYLKKRLSEVAEIPFDGVNFKDV 388
                    V V A  +I ++G  G+  + E+ + N  YLKK++ +  EIP++G    + 
Sbjct: 316 FG----NFPVLVKAYTYILTMGRDGLERVSEMAVLNANYLKKKIEKFLEIPYNGFCMHEF 371

Query: 389 LVRFEKPYKEIHE---ELLKRNIHGGYYVGK-HFPEL-GESALFAATETTRKEWVDALIS 443
           +   EK ++E      ++ KR +  G +    +FP +  E+ +   TET  KE +D    
Sbjct: 372 VASAEKVFRETGVRTLDIAKRILDFGVHPPTVYFPLIVPEALMIEPTETENKETLDKYAE 431

Query: 444 ALREVI 449
            L  V+
Sbjct: 432 ILERVV 437


>pir||D75030 probable glycine dehydrogenase (decarboxylating) (EC 1.4.4.2) chain
           2 PAB1172 - Pyrococcus abyssi (strain Orsay)
           >gi|5459196|emb|CAB50682.1| (AJ248288) PROBABLE GLYCINE
           DEHYDROGENASE (DECARBOXYLATING SUBUNIT 2 (EC 1.4.4.2)
           (GLYCINE DECARBOXYLASE) GLYCINE CLEAVAGE SYSTEM
           P-PROTEIN). [Pyrococcus abyssi]
           Length = 502
           
 Score =  102 bits (252), Expect = 8e-21
 Identities = 124/452 (27%), Positives = 201/452 (44%), Gaps = 55/452 (12%)

Query: 24  IDELFADIPGKFIRDE-LNLPEGKSEYEVFLEMNEILGKNKTVLEMPTFLGAGTYFHYIP 82
           I+++  +IP K  R   LNLPE  SE EV      +   N  V      LG+ T      
Sbjct: 29  IEDVDVEIPEKLKRKSPLNLPE-VSEPEVVKHYTRLSEMNYGVDSGIYPLGSCT------ 81

Query: 83  AHVKYLIERSEFLTAYT------PYQPEIS-QGMLQALFEYQSLIAELVGL------PVV 129
             +KY  + +E L  +       PYQ E + QG L+ ++E +  + E+ G+      P  
Sbjct: 82  --MKYNPKINEELAGHPKVAYIHPYQDERTVQGALRIMWELEQWLKEITGMDRFTLQPAA 139

Query: 130 NASMYDWGTAMAEAALMTVRLHRGK--RKKFIVPRHTHPERLQVLETYAKGPGVEIETVK 187
            A+    G  + +A      L RG+  R + +VP   H          A   G ++  + 
Sbjct: 140 GANGEFTGVMIIKA----YHLDRGETQRNEMLVPDSAHGTN----PASAAMAGFKVIEIP 191

Query: 188 WNERGQVDIEDLKEKVKD-AAGVYVEIPNFFGLLEEEVREIGEIAHEAGA--YFVVGVDP 244
            NE G VD+E L+  V +  AG+ +  PN  G+ E+E+ EI +I H+AG   Y+      
Sbjct: 192 SNENGTVDLEALENAVSERTAGLMLTNPNTLGIFEDEIEEIAKIVHKAGGLLYYDGANLN 251

Query: 245 TILGIVEAPGELGADIV-VGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPGRLIGMTK 303
            ILG V  PG++G DIV +     F  P   GGP AG   V+  +K    +P     ++ 
Sbjct: 252 GILGKVR-PGDMGFDIVHLNLHKTFSTPHGGGGPGAGPVGVKEFLKDYLPVP----LVSY 306

Query: 304 DAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRGIRELGEVILK 363
           D E  R ++      +  + ++            V V A  ++  +G  G+RE+ EV + 
Sbjct: 307 DEENDRYYL------DYDVPKSIGKVKELFGNFAVLVRALTYLKVMGKDGLREVSEVAVL 360

Query: 364 NTAYLKKRLSEVA--EIPFDGVNFKDVLVRFEKPYKEIHEELL---KRNIHGGYYVGK-H 417
           N  YL ++L      E+P   +   +V+   E   +E     L   KR +  G +    +
Sbjct: 361 NANYLARKLKGTRGYELPHKELRKHEVVFSAEPMKRETGVRTLDVAKRLLDFGMHAPTIY 420

Query: 418 FPEL-GESALFAATETTRKEWVDALISALREV 448
           FP +  E+ +   TET  KE +DA + A++++
Sbjct: 421 FPLIVHEALMIEPTETVSKEELDAYVEAMKKI 452


>pir||B71216 probable glycine dehydrogenase subunit 2 - Pyrococcus horikoshii
           >gi|3258438|dbj|BAA31121.1| (AP000007) 502aa long
           hypothetical glycine dehydrogenase subunit 2 [Pyrococcus
           horikoshii]
           Length = 502
           
 Score =  100 bits (247), Expect = 3e-20
 Identities = 122/446 (27%), Positives = 197/446 (43%), Gaps = 43/446 (9%)

Query: 24  IDELFADIPGKFIRDE-LNLPEGKSEYEVFLEMNEILGKNKTVLEMPTFLGAGTYFHYIP 82
           I+++  +IP K  R   L LPE  SE EV      +   N  V      LG+ T   Y P
Sbjct: 29  IEDVKVEIPEKLKRKTPLELPE-VSEPEVVKHYTRLSEMNYGVDSGIYPLGSCT-MKYNP 86

Query: 83  AHVKYLIERSEFLTAYTPYQPEIS-QGMLQALFEYQSLIAELVGL------PVVNASMYD 135
             +   I     +    PYQ E + QG L+ ++E +  + E+ G+      P   A+   
Sbjct: 87  K-INEEIANHPKVAFIHPYQDERTVQGALKIMWELEQWLKEITGMDRFTLQPAAGANGEF 145

Query: 136 WGTAMAEAALMTVRLHRG--KRKKFIVPRHTHPERLQVLETYAKGPGVEIETVKWNERGQ 193
            G  + +A      L RG  +R + +VP   H          A   G ++  +  NE G 
Sbjct: 146 TGVMIIKA----YHLDRGDTQRTEILVPDSAHGTN----PASASMAGFKVVEIPSNENGT 197

Query: 194 VDIEDLKEKVKD-AAGVYVEIPNFFGLLEEEVREIGEIAHEAGA--YFVVGVDPTILGIV 250
           VD+E L+  V +  AG+ +  PN  G+ E+E+ EI +I H+ G   Y+       ILG V
Sbjct: 198 VDLEALENAVSERTAGLMLTNPNTLGIFEDEIEEIAKIVHKVGGLLYYDGANLNGILGKV 257

Query: 251 EAPGELGADIV-VGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPGRLIGMTKDAEGKR 309
             PG++G DIV +     F  P   GGP AG   V+  +K    +P     ++ D E  R
Sbjct: 258 R-PGDMGFDIVHLNLHKTFSTPHGGGGPGAGPVGVKEFLKDYLPVP----LVSYDEENDR 312

Query: 310 AFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRGIRELGEVILKNTAYLK 369
            ++      + ++ ++            V V A  ++  +G  G+RE+ EV + N  YL 
Sbjct: 313 YYL------DYNVPKSIGKVKELFGNFAVLVKALTYLKIMGKEGLREVSEVAVLNANYLA 366

Query: 370 KRLSEVA--EIPFDGVNFKDVLVRFEKPYKEIHEELL---KRNIHGGYYVGK-HFPEL-G 422
           ++L      E+P   +   +V+   E   KE     L   KR +  G +    +FP +  
Sbjct: 367 RKLKGTRGYELPHKELRKHEVVFSAEPMKKETGVRTLDVAKRLLDFGLHAPTIYFPLIVH 426

Query: 423 ESALFAATETTRKEWVDALISALREV 448
           E+ +   TE+  KE +DA + AL+++
Sbjct: 427 EALMIEPTESVSKEELDAYVEALKKI 452


>emb|CAC12478.1| (AL445067) glycine dehydrogenase (decarboxylating) related protein,
           subunit 2 [Thermoplasma acidophilum]
           Length = 472
           
 Score = 97.1 bits (238), Expect = 4e-19
 Identities = 118/457 (25%), Positives = 201/457 (43%), Gaps = 44/457 (9%)

Query: 11  HKEEMLKEIGLSSIDELFADI-----PGKFIRDELNLPEGKSEYEVFLEMNEILGKNKTV 65
           + E ++K+I   +  +L  D+     P    R +L LP+  SE +V      +   N TV
Sbjct: 8   YDEPLIKDIKSDTSFKLSEDVDENLLPQDMRRTDLKLPQ-VSEVDVVRHYTRLSQMNYTV 66

Query: 66  LEMPTFLGAGTYFHYIPAHVKYLIERSEFLTAYTPYQPEIS-QGMLQALFEYQSLIAELV 124
                 LG+ T   Y P +   +   +EF   + P+QPE + QG LQ ++E Q  + ++ 
Sbjct: 67  DVGIYPLGSCT-MKYNPKYADRIASFAEFRNIH-PFQPESTVQGTLQIMYELQEFLKKIS 124

Query: 125 GLPVVNASMYDWGTAMAEAALMTVR----LHRGKRKKFIVPRHTHPERLQVLETYAKGPG 180
            +  V               L+  +    LH   R + IVP   H          A   G
Sbjct: 125 DMDAVTLQPMAGADGEFTGILIIKKYFEDLHED-RTEIIVPDSAHGTN----PASATMGG 179

Query: 181 VEIETVKWNERGQVDIEDLKEKV-KDAAGVYVEIPNFFGLLEEEVREIGEIAHEAGA-YF 238
            ++  +  N  G VD+  LK  + K  A + +  PN  G+ E+ + EI +I H+AGA  +
Sbjct: 180 FDVVEIPSNSEGMVDLNALKAAISKKTAALMITNPNTLGIFEQNITEIAKILHDAGALLY 239

Query: 239 VVGVDPTILGIVEAPGELGADIV-VGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPGR 297
             G +   +  + +PG +G DIV       F  P   GGP AG  AV++ +     +P  
Sbjct: 240 YDGANLNAIFGITSPGLMGFDIVHFNLHKSFATPHGGGGPGAGPVAVKSFLSDFLPVP-- 297

Query: 298 LIGMTKDAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRGIREL 357
           ++G     +GKR F+     +++ I R  +     S    + + A  ++   G  G++  
Sbjct: 298 VVGY----DGKRYFLD--YGKKKSIGRVSSFYGSFS----ILLRAWSYVIRNGDDGLKNA 347

Query: 358 GEVILKNTAYLKKRLSEVAEIPFDGVNFKDVLVRFEKPYK---EIHEELLKRNIHGGYYV 414
               + N+ YLKK++    E+P+  +   + ++  EK  +   +I + LL   IH     
Sbjct: 348 TIRAVLNSNYLKKKVEGYYEVPYYPLKKHEFVLSTEKTGRRALDIGKYLLDFGIHSPTV- 406

Query: 415 GKHFPEL-GESALFAATETTRKE----WVDALISALR 446
             +FP +  E+ +   TET  K+    + D LISAL+
Sbjct: 407 --YFPLIVKEAMMIEPTETVSKDDLDRYADVLISALK 441


>gb|AAK41199.1| Glycine dehydrogenase subunit 2 [Sulfolobus solfataricus]
           Length = 508
           
 Score = 89.7 bits (219), Expect = 6e-17
 Identities = 102/394 (25%), Positives = 169/394 (42%), Gaps = 54/394 (13%)

Query: 85  VKYLIERSEFLTAYTPYQPEIS-----QGMLQALFEYQSLIAELVGLPVVNASMYDWGTA 139
           +KY  +  E  TA T +   +      QG+L+ ++E Q+  +E+ G+   +  +      
Sbjct: 88  MKYNPKIEEKATAITEFHHPLEDEDYIQGILEMIYELQNWFSEITGMDECSLQVPAGSAG 147

Query: 140 MAEAALMTVRLH----RGKRKKFIVPRHTHPERLQVLETYAKGPGVEIETVKWNERGQVD 195
                LM  + H    R  +   +V    H          A   G ++  VK N  G VD
Sbjct: 148 EFAGVLMIKKYHEEHNRNYKDTILVADTAHGTN----PASAAMAGYKVMYVKSNAEGLVD 203

Query: 196 IEDLKEKVKD-AAGVYVEIPNFFGLLEEEVREIGEIAHEAGA--YFVVGVDPTILGIVEA 252
           ++ L+E V D  AG  +  PN  GL EE + EI +I H   A  Y+       +LGI   
Sbjct: 204 MDILREIVNDKTAGFMLTNPNTLGLFEENILEISKIIHSTNAVLYYDGANLNGVLGIAR- 262

Query: 253 PGELGADIV-VGEASYFGNPMNFGGPRAGIFAVRNDM------KLIRQMPGR--LIGMTK 303
           PG++G DIV +     F  P   GGP AG    + ++       ++ ++ G+  L  + K
Sbjct: 263 PGDMGFDIVHLNLHKTFAVPHGGGGPGAGAICAKGELVNYLPYPMVEKVNGKYKLSKIPK 322

Query: 304 DAEGKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHIASLGPRGIRELGEVILK 363
           ++ GK   + T      ++ R+ A                 +I  LGP+GI+ +G++   
Sbjct: 323 NSIGK---IATFYGNVGNLARSFA-----------------YILGLGPQGIQMIGKMSTL 362

Query: 364 NTAYLKKRLSEVAEIPFDGVN--FKDVLVRFEKPYKEIH----EELLKRNIHGGYYVGK- 416
            T YL  +L +V E+     N   K  +V   K   E +     ++ K  +  G+Y    
Sbjct: 363 ATNYLIAKLRDVKELELIAPNRHRKHEVVFSVKQLMENYGVSANDVAKALLDNGFYAPTI 422

Query: 417 HFPELGESAL-FAATETTRKEWVDALISALREVI 449
           +FP + E AL    TET  KE +D     L++++
Sbjct: 423 YFPPIVEEALMIEPTETETKETLDMFAETLKKIV 456


>gb|AAB97081.1| (AF042072) glycine decarboxylase P subunit [Coffea arabica]
           >gi|2827422|gb|AAB99846.1| (AF043099) glycine
           decarboxylase multi-enzyme complex P subunit [Coffea
           eugenioides]
           Length = 142
           
 Score = 88.5 bits (216), Expect = 1e-16
 Identities = 55/142 (38%), Positives = 81/142 (56%), Gaps = 11/142 (7%)

Query: 8   NSAHKEEMLKEI---GLSSIDELF-ADIPGKFIRDELNLP---EGKSEYEVFLEMNEILG 60
           NSA  EE +K +   G  S+D L  A +P     D +      EG +E ++   M ++  
Sbjct: 4   NSATPEEQIKMVENCGFPSLDSLIDATVPKSIRLDGMTFSKFDEGLTEAQMIDHMQKLAS 63

Query: 61  KNKTVLEMPTFLGAGTYFHYIPAHV-KYLIERSEFLTAYTPYQPEISQGMLQALFEYQSL 119
           KNK      +++G G Y  ++P  + + L+E   + T YTPYQ EISQG L++L  YQ++
Sbjct: 64  KNKV---FKSYIGMGYYNTFVPPVILRNLLENPAWYTQYTPYQAEISQGRLESLLNYQTM 120

Query: 120 IAELVGLPVVNASMYDWGTAMA 141
           IA+L GLP+ NAS+ D GTA A
Sbjct: 121 IADLTGLPMSNASLLDEGTAAA 142


>gb|AAB99844.1| (AF043097) glycine decarboxylase multi-enzyme complex P subunit
           [Coffea canephora]
           Length = 142
           
 Score = 88.5 bits (216), Expect = 1e-16
 Identities = 55/142 (38%), Positives = 81/142 (56%), Gaps = 11/142 (7%)

Query: 8   NSAHKEEMLKEI---GLSSIDELF-ADIPGKFIRDELNLP---EGKSEYEVFLEMNEILG 60
           NSA  EE +K +   G  S+D L  A +P     D +      EG +E ++   M ++  
Sbjct: 4   NSATPEEQIKMVENCGFPSLDSLIDATVPKSIRLDGMTFSKFDEGLTEAQMIDHMEKLAS 63

Query: 61  KNKTVLEMPTFLGAGTYFHYIPAHV-KYLIERSEFLTAYTPYQPEISQGMLQALFEYQSL 119
           KNK      +++G G Y  ++P  + + L+E   + T YTPYQ EISQG L++L  YQ++
Sbjct: 64  KNKV---FKSYIGMGYYNTFVPPVILRNLLENPAWYTQYTPYQAEISQGRLESLLNYQTM 120

Query: 120 IAELVGLPVVNASMYDWGTAMA 141
           IA+L GLP+ NAS+ D GTA A
Sbjct: 121 IADLTGLPMSNASLLDEGTAAA 142


>gb|AAB99845.1| (AF043098) glycine decarboxylase multi-enzyme complex P subunit
           [Coffea congensis]
           Length = 142
           
 Score = 88.5 bits (216), Expect = 1e-16
 Identities = 55/142 (38%), Positives = 81/142 (56%), Gaps = 11/142 (7%)

Query: 8   NSAHKEEMLKEI---GLSSIDELF-ADIPGKFIRDELNLP---EGKSEYEVFLEMNEILG 60
           NSA  EE +K +   G  S+D L  A +P     D +      EG +E ++   M ++  
Sbjct: 4   NSATPEEQIKMVENCGFPSLDSLIDATVPKSIRLDGMTFSKFDEGLTEAQMIDHMEKLAS 63

Query: 61  KNKTVLEMPTFLGAGTYFHYIPAHV-KYLIERSEFLTAYTPYQPEISQGMLQALFEYQSL 119
           KNK      +++G G Y  ++P  + + L+E   + T YTPYQ EISQG L++L  YQ++
Sbjct: 64  KNKV---FKSYIGMGYYNTFVPPVILRNLLENPAWYTQYTPYQAEISQGRLESLLNYQTM 120

Query: 120 IAELVGLPVVNASMYDWGTAMA 141
           IA+L GLP+ NAS+ D GTA A
Sbjct: 121 IADLTGLPMSNASLLDEGTAAA 142


>pir||H70463 glycine dehydrogenase (decarboxylating) - Aquifex aeolicus
           >gi|2984168|gb|AAC07701.1| (AE000762) glycine
           dehydrogenase (decarboxylating) [Aquifex aeolicus]
           Length = 482
           
 Score = 87.8 bits (214), Expect = 2e-16
 Identities = 103/434 (23%), Positives = 187/434 (42%), Gaps = 37/434 (8%)

Query: 31  IPGKFIRDELNLPEGKSEYEVFLEMNEILGKNKTVLEMPTFLGAGTYFHYIPAHVKYLIE 90
           +P +++R+EL+ PE  SE +V      +   N  V      LG+ T   Y P   + L+ 
Sbjct: 31  LPEEYLREELDFPE-VSELDVVRHYTNLSHLNYAVDTTMVPLGSCT-MKYNPRINEELVN 88

Query: 91  RSEFLTAYTPYQPEISQGMLQALFEYQSLIAELVGLPVVNASMYDWGTAMAEAALMTVRL 150
           + EFL  +     E  Q +L+ ++E + L+ EL G   V+              L+    
Sbjct: 89  KKEFLNVHPLTPEEYIQPLLKLVYELKELLKELGGFAEVSLQPAAGAHGELLGLLLIHAY 148

Query: 151 H--RGKRKK--FIVPRHTHPERLQVLETYAKGPGVEIETVKWNERGQVDIEDLKEKVKD- 205
           H  RG ++K   ++P   H          A   G +I+ VK +++G++D ED  +K+ + 
Sbjct: 149 HQDRGNKEKKVVLIPDSAHGTN----PASAAICGFDIKVVKSDKKGELDFEDFIKKLDER 204

Query: 206 AAGVYVEIPNFFGLLEEEVREIGEIAHEAGA-YFVVGVDPTILGIVEAPGELGADIV-VG 263
            A + +  PN  G+ E +++EI E  H+  A  ++ G +   L     PGE G D++   
Sbjct: 205 VAALMITNPNTLGIFERKIKEIAEELHKRDALLYMDGANFNALVGRFKPGEWGVDVMHFN 264

Query: 264 EASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPGRLIGMTKDAEGKRAFVMTLQTREQHIR 323
               F  P   GGP AG   V   +K    +P        + +GK+ ++        +I 
Sbjct: 265 LHKTFSTPHGGGGPGAGPVGVSERLKPYLPVP------QIEYDGKKYYL------NWNIE 312

Query: 324 RAKATSNICSNEALVAVAAAIHIASLGPRGIRELGEVILKNTAYLKKRLSEVAEIPF--- 380
           ++           LV + A  +I + G + I+++ E  + N  YLK  L  V + P+   
Sbjct: 313 KSVGKILAFHGHFLVWLKALAYILTYG-KDIKKVSEYAVLNARYLKHLLKGVFKDPYPES 371

Query: 381 ----DGVNFKDVLVRFEKPYKEIHEELLKRNIHGGYYVGKHFPEL-GESALFAATETTRK 435
               + V     L ++     ++ + +L    +G Y    +FP +  E+ +   TET   
Sbjct: 372 PCMHEFVLSATNLTKYGVRASDVAKRILD---YGFYAPTMYFPLIVREALMIEPTETENP 428

Query: 436 EWVDALISALREVI 449
           + +      LR+++
Sbjct: 429 DTLKKFALILRKIV 442


>pir||D72518 probable glycine dehydrogenase subunit 2 APE2121 - Aeropyrum pernix
           (strain K1) >gi|5105820|dbj|BAA81132.1| (AP000063) 521aa
           long hypothetical glycine dehydrogenase subunit 2
           [Aeropyrum pernix]
           Length = 521
           
 Score = 84.7 bits (206), Expect = 2e-15
 Identities = 124/462 (26%), Positives = 189/462 (40%), Gaps = 50/462 (10%)

Query: 13  EEMLKEIGLSSIDELFADIPGKFIRDELNLPEGKSEYEVFLEMNEILGKNKTVLEMPTFL 72
           E+++KE+G   + +  A           +LPE  SE EV      +      V   P  L
Sbjct: 31  EKVVKEVGPLKLPQSLAR------GSPPSLPE-VSEVEVVRHYTRLSQMAYGVDNGPVPL 83

Query: 73  GAGTYFHYIPAHVKYLIERSEFLTAYTPYQPEISQGMLQALFEYQSLIAELVGLPVVNAS 132
           G+ T   Y P     L       T +     E  QG+L+A++  Q  +  + G+      
Sbjct: 84  GSCT-MKYNPRVAARLAFDPRLETLHPLQDDETVQGVLEAIYMVQEWLRHITGMDACTVH 142

Query: 133 MYDWGTAMAEAALMTVRLH--RG---KRKKFIVPRHTHPERLQVLETYAKGPGVEIETVK 187
                       LM  R H  RG   KR+  IVP   H          A   G ++  V 
Sbjct: 143 PAAGSQGELAGVLMIKRFHEMRGDLDKRRVIIVPDSAHGTN----PASAAMGGFQVVEVP 198

Query: 188 WNERGQVDIEDLKEKVK-DAAGVYVEIPNFFGLLEEEVREIGEIAHEAGAYFVVGVDPTI 246
             + G VD+E LK  V  D AG+ +  P+  GL EE + EI  + HEAG          +
Sbjct: 199 TGDDGNVDMEALKAAVGGDTAGLMITNPSTLGLFEENILEISRLVHEAGGLLYYD-GANL 257

Query: 247 LGIV--EAPGELGADIV-VGEASYFGNPMNFGGPRAGIFAVRNDMKLIRQMPGRLIGMTK 303
            GI+    PG++  DI  V     F  P   GGP +G   V    K +  + G  + +  
Sbjct: 258 NGIIGRARPGDMEFDIAHVNLHKTFSVPHGGGGPGSGPVCV----KRVEVVDG--VTLED 311

Query: 304 DAEGKRAFVMTLQTREQHIRRAKATS--NICSNEALVAVAAAI-----HIASLGPRGIRE 356
              G R     + +RE+ + R +     ++    A +A   A+     +I ++GP+G+R 
Sbjct: 312 LLPGPR----VVYSREEGLYRVRPPGRWSVGRLRAWIANTLAVLWAYAYILAMGPQGLRL 367

Query: 357 LGEVILKNTAYLKKRLSE---VAEIPF-DGVNFKDVLVRFEKPYKE----IHEELLKRNI 408
            GEV + NT Y   RL E      +P+      K  +V   KP K       E++ K  +
Sbjct: 368 AGEVSVVNTNYF-IRLMEGHWGYSLPYAPSRPRKHEVVLSAKPLKRETGATAEDVAKGLL 426

Query: 409 HGGYYVGK-HFPELGESALFAA-TETTRKEWVDALISALREV 448
             G Y    +FP + E AL    TE+  KE ++A  + L+E+
Sbjct: 427 DAGLYAPTIYFPLIVEEALMIEFTESETKENIEAYAARLKEI 468


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.319    0.138    0.397 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 166853912
Number of Sequences: 2977
Number of extensions: 7347028
Number of successful extensions: 19858
Number of sequences better than 1.0e-10: 54
Number of HSP's better than  0.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 19634
Number of HSP's gapped (non-prelim): 84
length of query: 449
length of database: 189,106,746
effective HSP length: 57
effective length of query: 392
effective length of database: 154,992,987
effective search space: 60757250904
effective search space used: 60757250904
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 166 (69.1 bits)