BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB1190 (alaRS-like) DE:alanyl-tRNA synthetase related protein
(fragment)
(405 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||G75027 alanyl-tRNA synthetase related protein PAB1190 - Pyr... 825 0.0
pir||A71213 alanine--tRNA ligase truncated homolog PH1969 - Pyro... 571 e-162
pir||B75017 alanyl-tRNA synthetase (alas) PAB1245 - Pyrococcus a... 157 3e-37
sp|O58035|SYA_PYRHO ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 154 2e-36
gi|11499836 alanyl-tRNA synthetase (alaS) [Archaeoglobus fulgidu... 140 3e-32
pir||E72216 alanine--tRNA ligase truncated homolog TM1726 - Ther... 135 1e-30
sp|Q57984|SYA_METJA ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 130 3e-29
pir||A75198 alanine--tRNA ligase truncated homolog PAB0066 - Pyr... 127 2e-28
gb|AAK40671.1| Alanyl-tRNA synthetase (alaS) [Sulfolobus solfata... 125 7e-28
pir||B71231 alanine--tRNA ligase truncated homolog PH0108 - Pyro... 125 9e-28
sp|O67323|SYA_AQUAE ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 120 3e-26
sp|Q9XDM3|SYA_AQUPY ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 118 1e-25
sp|Q9Y9X3|SYA_AERPE ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 118 1e-25
gb|AAA03208.1| (J01581) alanyl-tRNA synthetase [Escherichia coli] 113 4e-24
sp|P00957|SYA_ECOLI ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 112 8e-24
sp|Q9X1B6|SYA_THEMA ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 110 2e-23
sp|P74423|SYA_SYNY3 ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 109 4e-23
gb|AAG20397.1| (AE005112) alanyl-tRNA synthetase; AlaS [Halobact... 109 4e-23
gi|6324288 Ynl040wp [Saccharomyces cerevisiae] >gi|1730724|sp|P5... 108 1e-22
sp|O34526|SYA_BACSU ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 106 6e-22
pir||H83533 alanyl-tRNA synthetase PA0903 [imported] - Pseudomon... 106 6e-22
dbj|BAB06653.1| (AP001517) unknown conserved protein in others [... 106 6e-22
emb|CAC11271.1| (AL445063) alanyl-tRNA synthetase related protei... 105 1e-21
sp|P57483|SYA_BUCAI ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 101 2e-20
dbj|BAB04986.1| (AP001511) alanyl-tRNA synthetase [Bacillus halo... 100 3e-20
pir||A83382 hypothetical protein PA2106 [imported] - Pseudomonas... 100 4e-20
gb|AAK40776.1| Alanyl-tRNA synthetase truncated homolog (alaS-li... 100 5e-20
sp|P43815|SYA_HAEIN ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 100 5e-20
sp|Q56273|SYA_THIFE ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 94 2e-18
pir||G72685 probable alanyl-tRNA synthetase APE0903 - Aeropyrum ... 94 2e-18
pir||C75511 alanyl-tRNA synthetase-related protein - Deinococcus... 94 4e-18
emb|CAC11978.1| (AL445065) alanyl-tRNA synthetase related protei... 92 8e-18
sp|O27718|SYA_METTH ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 92 1e-17
pir||H81739 alanyl-tRNA synthetase TC0125 [imported] - Chlamydia... 91 2e-17
pir||F81063 alanyl-tRNA synthetase NMB1595 [imported] - Neisseri... 91 2e-17
sp|O84754|SYA_CHLTR ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 89 7e-17
pir||E71476 alanine--tRNA ligase (EC 6.1.1.7) - Chlamydia tracho... 89 7e-17
dbj|BAB10601.1| (AB005243) alanyl-tRNA synthetase [Arabidopsis t... 89 7e-17
sp|O07438|SYA_MYCTU ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 89 9e-17
gb|AAG23689.1|AF297520_1 (AF297520) alanyl-tRNA synthase [Haemop... 89 1e-16
pir||C81804 alanine--tRNA ligase (EC 6.1.1.7) NMA1788 [imported]... 87 5e-16
sp|P74941|SYA_THETH ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 85 2e-15
pir||C81396 alanine--tRNA ligase (EC 6.1.1.7) Cj0506 [imported] ... 83 5e-15
emb|CAB93381.1| (AL357523) alanine tRNA synthetase [Streptomyces... 83 5e-15
pir||G82310 alanyl-tRNA synthetase VC0545 [imported] - Vibrio ch... 79 1e-13
sp|P21894|SYA_BOMMO ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 78 2e-13
emb|CAC11640.1| (AL445064) conserved hypothetical protein [Therm... 76 5e-13
sp|Q9ZCA4|SYA_RICPR ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 76 7e-13
gb|AAF45874.1| (AE003427) CG10802 gene product [Drosophila melan... 75 1e-12
pir||F75289 alanyl-tRNA synthetase - Deinococcus radiodurans (st... 75 2e-12
sp|P27866|SYA_RHIME ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 74 3e-12
sp|P70865|SYA_BARBA ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 74 3e-12
sp|Q9ZJY5|SYA_HELPJ ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 73 8e-12
gb|AAF52657.1| (AE003621) Aats-ala gene product [Drosophila mela... 72 1e-11
pir||C82844 alanyl-tRNA synthetase XF0124 [imported] - Xylella f... 72 1e-11
gb|AAC49007.1| (U18672) cytoplasmic alanyl-tRNA synthetase [Sacc... 72 1e-11
gi|6324911 Cytoplasmic alanyl-tRNA synthetase gene; Ala1p [Sacch... 72 1e-11
gb|AAD53924.1|AF179611_8 (AF179611) alanyl-tRNA synthetase [Zymo... 71 2e-11
gb|AAF05594.1|AF188719_1 (AF188719) alanyl-tRNA synthetase [Giar... 70 4e-11
gb|AAG23137.1|AF245445_1 (AF245445) alanyl-tRNA synthetase [Giar... 70 4e-11
sp|P56452|SYA_HELPY ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 70 5e-11
>pir||G75027 alanyl-tRNA synthetase related protein PAB1190 - Pyrococcus abyssi
(strain Orsay) >gi|5459175|emb|CAB50661.1| (AJ248288)
alanyl-tRNA synthetase related protein (fragment)
[Pyrococcus abyssi]
Length = 405
Score = 825 bits (2107), Expect = 0.0
Identities = 405/405 (100%), Positives = 405/405 (100%)
Query: 1 MARKLYYVDPYLKTAKAKISDLTIKGDKIEVSLTETIFYPRGGGQPGDKGKIRGDGFEII 60
MARKLYYVDPYLKTAKAKISDLTIKGDKIEVSLTETIFYPRGGGQPGDKGKIRGDGFEII
Sbjct: 1 MARKLYYVDPYLKTAKAKISDLTIKGDKIEVSLTETIFYPRGGGQPGDKGKIRGDGFEII 60
Query: 61 VEDTVERDGEIWHVGKLNGRTPEVGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRYDL 120
VEDTVERDGEIWHVGKLNGRTPEVGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRYDL
Sbjct: 61 VEDTVERDGEIWHVGKLNGRTPEVGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRYDL 120
Query: 121 DTSGFNIFGDYAKIEVNGELNWEMIEEAELEANKVIIDDLPVRVEEYEVLPKGVVEKLRK 180
DTSGFNIFGDYAKIEVNGELNWEMIEEAELEANKVIIDDLPVRVEEYEVLPKGVVEKLRK
Sbjct: 121 DTSGFNIFGDYAKIEVNGELNWEMIEEAELEANKVIIDDLPVRVEEYEVLPKGVVEKLRK 180
Query: 181 YIPNIKGKIRIVRIGENFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFTCGFRA 240
YIPNIKGKIRIVRIGENFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFTCGFRA
Sbjct: 181 YIPNIKGKIRIVRIGENFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFTCGFRA 240
Query: 241 IKKLNEILKDYWSALDAMPNKNPPLSERVREVLESVESLEEKVDSMRKEVWKWKEESLLG 300
IKKLNEILKDYWSALDAMPNKNPPLSERVREVLESVESLEEKVDSMRKEVWKWKEESLLG
Sbjct: 241 IKKLNEILKDYWSALDAMPNKNPPLSERVREVLESVESLEEKVDSMRKEVWKWKEESLLG 300
Query: 301 RSIEIGHYNVVTFVEKWDIKDAQAFAVDFVKNNPGTIVVLASEDYVILARNEEVEVSMKS 360
RSIEIGHYNVVTFVEKWDIKDAQAFAVDFVKNNPGTIVVLASEDYVILARNEEVEVSMKS
Sbjct: 301 RSIEIGHYNVVTFVEKWDIKDAQAFAVDFVKNNPGTIVVLASEDYVILARNEEVEVSMKS 360
Query: 361 LLEDLIKEFGGKGGGTDNLARGKIEAEPEDVIDFVVDRLREIIGA 405
LLEDLIKEFGGKGGGTDNLARGKIEAEPEDVIDFVVDRLREIIGA
Sbjct: 361 LLEDLIKEFGGKGGGTDNLARGKIEAEPEDVIDFVVDRLREIIGA 405
>pir||A71213 alanine--tRNA ligase truncated homolog PH1969 - Pyrococcus
horikoshii >gi|3258413|dbj|BAA31096.1| (AP000007) 404aa
long hypothetical alanyl-tRNA synthetase [Pyrococcus
horikoshii]
Length = 404
Score = 571 bits (1456), Expect = e-162
Identities = 259/400 (64%), Positives = 334/400 (82%), Gaps = 1/400 (0%)
Query: 1 MARKLYYVDPYLKTAKAKISDLTIKGDKIEVSLTETIFYPRGGGQPGDKGKIRGDGFEII 60
M ++YY DPYL+ AKI D+ + D++EV L TIFYP GGGQPGD+G I+G+ FEI+
Sbjct: 1 MVERVYYKDPYLREIDAKIVDVRKEKDRVEVVLDRTIFYPEGGGQPGDRGVIKGNDFEIM 60
Query: 61 VEDTVERDGEIWHVGKLNGRTPEVGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRYDL 120
VEDT+E++GEI+H+GKL G P+ GE+V+L LDWEWRYGNMQMHTGQHILSAVLKK YDL
Sbjct: 61 VEDTIEKNGEIFHIGKLRGEIPKEGEKVKLYLDWEWRYGNMQMHTGQHILSAVLKKLYDL 120
Query: 121 DTSGFNIFGDYAKIEVNGELNWEMIEEAELEANKVIIDDLPVRVEEYEVLPKGVVEKLRK 180
DT+GFNIF DYAKIEVNGE+NW+MIE AELE NK+II+DLPV +EEY+ LP+ + KLRK
Sbjct: 121 DTTGFNIFRDYAKIEVNGEVNWDMIERAELEVNKIIINDLPVVIEEYDKLPEEIALKLRK 180
Query: 181 YIPNIKGKIRIVRIGENFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFTCGFRA 240
+ +K KIRIV+IG+ D+TPCGGTHVKSTREVG+IKVLRFYKKSK+ WRIEFTCG+RA
Sbjct: 181 NVTKVKEKIRIVKIGD-VDVTPCGGTHVKSTREVGIIKVLRFYKKSKNLWRIEFTCGYRA 239
Query: 241 IKKLNEILKDYWSALDAMPNKNPPLSERVREVLESVESLEEKVDSMRKEVWKWKEESLLG 300
I K+NEIL+DYW +LD MPNKNPPL ER+ EVL +V SLE +++ +R+E+W+WK ++LL
Sbjct: 240 ISKMNEILRDYWGSLDLMPNKNPPLIERINEVLRTVNSLENRIEELRREIWEWKGKALLK 299
Query: 301 RSIEIGHYNVVTFVEKWDIKDAQAFAVDFVKNNPGTIVVLASEDYVILARNEEVEVSMKS 360
+++G+Y V+T VE W++KDAQAFA+DFVK N TI++LA+E YV+ A+NE V VSM+
Sbjct: 300 EGVKVGNYTVITHVENWNMKDAQAFAIDFVKKNSNTILLLANEKYVLFAKNEGVPVSMRE 359
Query: 361 LLEDLIKEFGGKGGGTDNLARGKIEAEPEDVIDFVVDRLR 400
LL+++I E GGKGGGTDNLARG++EA+PE++ D +++LR
Sbjct: 360 LLKEVIDELGGKGGGTDNLARGRVEAKPEEIFDVALEKLR 399
>pir||B75017 alanyl-tRNA synthetase (alas) PAB1245 - Pyrococcus abyssi (strain
Orsay) >gi|5459090|emb|CAB50576.1| (AJ248288)
alanyl-tRNA synthetase (alaS) [Pyrococcus abyssi]
Length = 914
Score = 157 bits (392), Expect = 3e-37
Identities = 126/411 (30%), Positives = 213/411 (51%), Gaps = 27/411 (6%)
Query: 3 RKLYYVDPYLKTAKAKISDLTIKGDKIEVSLTETIFYPRGGGQPGDKGKIRGDGFEIIVE 62
R LYY DP++K +A++ L + GD I L +T FYP GGGQP D G + +G E+ V
Sbjct: 517 RTLYYEDPFMKEFEARV--LRVIGDWIV--LDQTAFYPEGGGQPYDTGVLFVNGSEVKVT 572
Query: 63 DTVERDGEIWHVGKLNGRTPEVGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRYDLDT 122
+ + I H + G E G EV +DW+ R +M+ HTG H+L L +
Sbjct: 573 NVQKVGKVIVHKVENPGLFKE-GMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHV 631
Query: 123 --SGFNIFGDYAKIEVNG--ELNWEMIEEAELEANKVIIDDLPVRVEEYEVLPKGVVEK- 177
+G + D+A+++++ ++ E + E E AN+++++D V +E LP+ E+
Sbjct: 632 WQAGSQLTTDWARLDISHYKRISDEELREIERLANRIVMEDRKVT---WEWLPRTEAEQR 688
Query: 178 --LRKYIPNI-KGK-IRIVRIGENFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIE 233
R Y + G+ IR+V+I E++D+ CGGTH+ ST VG IK+LR + RI
Sbjct: 689 YGFRLYQGGVVPGRVIRVVKI-EDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERII 747
Query: 234 FTCGFRAIK---KLNEILKDYWSALDAMPNKNPPLSERVREVLESVESLEEKVDSMRKEV 290
F CG AIK K EILK L P K P +ER + ++V+ ++KE+
Sbjct: 748 FACGEAAIKEWQKEREILKKASQVLRVPPEKLPETAER---FFNEWKEARKEVEKLKKEL 804
Query: 291 WKWKEESLLGRSIEIGHYNVVTFVEKWDIKDAQAFAVDFVKNNPGTIVVLASEDYVILAR 350
K L + ++ Y + + + + D + AV+ +K +V+++ E Y ++
Sbjct: 805 AKLLVYELEAKVQKVKEYEFIGEIVEGSMDDLRE-AVERLKKPNRIVVLVSKEGYFAISV 863
Query: 351 NEEVEVSMKSLLEDLIKEFGGKGGGTDNLARGKIE--AEPEDVIDFVVDRL 399
+ V ++ L + L GG GGG ++A+G+I+ ++ ++ I+ +V L
Sbjct: 864 GDNVNLNANDLAKKLTSIAGGGGGGRKDVAQGRIKDVSKAKEAIESIVKLL 914
>sp|O58035|SYA_PYRHO ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|7437626|pir||C71455 alanine--tRNA ligase (EC
6.1.1.7) - Pyrococcus horikoshii
>gi|3256687|dbj|BAA29370.1| (AP000001) 915aa long
hypothetical alanyl-tRNA synthetase [Pyrococcus
horikoshii]
Length = 915
Score = 154 bits (385), Expect = 2e-36
Identities = 121/407 (29%), Positives = 211/407 (51%), Gaps = 27/407 (6%)
Query: 3 RKLYYVDPYLKTAKAKISDLTIKGDKIEVSLTETIFYPRGGGQPGDKGKIRGDGFEIIVE 62
R+LYY DP++K AK+ ++ K V L T FYP GGGQP D G + +G E+ V
Sbjct: 517 RRLYYEDPFMKEFDAKV----LRVIKDWVILDATAFYPEGGGQPYDTGVLIVNGREVKVT 572
Query: 63 DTVERDGEIWHVGKLNGRTPEVGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRYDLDT 122
+ + I H + G E G V ++DW+ R +M+ HTG H+L L +
Sbjct: 573 NVQKVGKVIIHKVEDPGAFKE-GMIVHGKIDWKRRIQHMRHHTGTHVLMGALVRVLGRHV 631
Query: 123 --SGFNIFGDYAKIEVNG--ELNWEMIEEAELEANKVIIDDLPVRVEEYEVLPKGVVEK- 177
+G + D+A+++++ ++ E ++E E+ AN+++++D V +E LP+ E+
Sbjct: 632 WQAGSQLTTDWARLDISHYKRISEEELKEIEMLANRIVMEDRKVT---WEWLPRTTAEQK 688
Query: 178 --LRKYIPNIKG--KIRIVRIGENFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIE 233
R Y + +IR+V+I E++D+ CGGTH+ ST VG IK+LR + RI
Sbjct: 689 YGFRLYQGGVVPGREIRVVKI-EDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERII 747
Query: 234 FTCGFRAIK---KLNEILKDYWSALDAMPNKNPPLSERVREVLESVESLEEKVDSMRKEV 290
F CG AI+ K ++LK + L P K P +ER + ++VD ++KE+
Sbjct: 748 FACGEAAIREWQKERDLLKKASNVLRVPPEKLPETAER---FFNEWKEARKEVDKLKKEL 804
Query: 291 WKWKEESLLGRSIEIGHYNVVTFVEKWDIKDAQAFAVDFVKNNPGTIVVLASEDYVILAR 350
+ L + +IG + V + ++D + V+ +K +V+++ + Y ++
Sbjct: 805 ARLLVYELESKMQKIGSIEFIGEVVEGSMEDLREL-VEKLKKPKRVVVLISRDGYFAVSV 863
Query: 351 NEEVEVSMKSLLEDLIKEFGGKGGGTDNLARGKIE--AEPEDVIDFV 395
EV V L + + GG GGG ++A+GK++ ++ +DVI+ +
Sbjct: 864 GSEVGVEANELAKKITLIAGGGGGGRRDIAQGKVKDISKAKDVIESI 910
>gi|11499836 alanyl-tRNA synthetase (alaS) [Archaeoglobus fulgidus]
>gi|3334348|sp|O28029|SYA_ARCFU ALANYL-TRNA SYNTHETASE
(ALANINE--TRNA LIGASE) (ALARS) >gi|7437618|pir||G69531
alanyl-tRNA synthetase (alaS) homolog - Archaeoglobus
fulgidus >gi|2648270|gb|AAB89002.1| (AE000949)
alanyl-tRNA synthetase (alaS) [Archaeoglobus fulgidus]
Length = 906
Score = 140 bits (349), Expect = 3e-32
Identities = 112/409 (27%), Positives = 198/409 (48%), Gaps = 22/409 (5%)
Query: 4 KLYYVDPYLKTAKAKISDLTIKGDKIEVSLTETIFYPRGGGQPGDKGKIRGDGFEIIVED 63
KLYY DP L +A++ + ++GD V L + FYP GGQ D G + +G + V D
Sbjct: 506 KLYYDDPTLLEFEAEV--IGVEGDF--VILNRSAFYPESGGQDNDVGYLIANGGKFEVVD 561
Query: 64 TVERDGEIWHVGKLNGRTPEVGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRYDLDTS 123
+E DG + HV K G PEVG +V+ +D + R+ +M+ H+ H+L L+K
Sbjct: 562 VLEADGVVLHVVK--GAKPEVGTKVKGVIDSDVRWRHMRHHSATHVLLYSLQKVLGNHVW 619
Query: 124 GFNIFGDYAKIEVN----GELNWEMIEEAELEANKVIIDDLPVRVEEYEVLPKGVVEKLR 179
+++K ++ + E I+E E+ AN+ I+ + P++ E + + R
Sbjct: 620 QAGARKEFSKARLDVTHFRRPSEEEIKEIEMLANREILANKPIKWEWMDRIEAERKFGFR 679
Query: 180 KYIPNIKG--KIRIVRIGENFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFTCG 237
Y + KIR+V++G+ D+ CGGTH +ST E+G++K+L+ R EF G
Sbjct: 680 LYQGGVPPGRKIRVVQVGD--DVQACGGTHCRSTGEIGMLKILKVESIQDGVIRFEFAAG 737
Query: 238 ---FRAIKKLNEILKDYWSALDAMPNKNPPLSERVREVLESVESLEEKVDSMRKEVWKWK 294
A++++ +L++ S L P K P ER E + E++ S+ ++W
Sbjct: 738 EAAIEAVEEMERLLREASSILRVEPAKLPKTVERFFEEWKDQRKEIERLKSVIADLW--- 794
Query: 295 EESLLGRSIEIGHYNVVTFVEKWDIKDAQAFAVDFVKNNPGTIVVLASEDYVILARNEEV 354
+ L+ R+ E VV V D++ Q A + ++ E V +
Sbjct: 795 ADILMERAEEFDSMKVVAEVVDADMQALQKLAERLAEKGAVGCLMAKGEGKVFVVTFSGQ 854
Query: 355 EVSMKSLLEDLIKEFGGKGGGTDNLARGKIE--AEPEDVIDFVVDRLRE 401
+ + LL ++ + G GGG ++A+G ++ + E+++D + L E
Sbjct: 855 KYDARELLREIGRVAKGSGGGRKDVAQGAVQQLLDREEMLDVIFRFLSE 903
>pir||E72216 alanine--tRNA ligase truncated homolog TM1726 - Thermotoga maritima
(strain MSB8) >gi|4982303|gb|AAD36791.1|AE001812_1
(AE001812) alanyl-tRNA synthetase-related protein
[Thermotoga maritima]
Length = 373
Score = 135 bits (336), Expect = 1e-30
Identities = 125/396 (31%), Positives = 196/396 (48%), Gaps = 30/396 (7%)
Query: 12 LKTAKAKISDLTIKGDKIEVSLTETIFYPRG-GGQPGDKGKIRGDGFEIIVEDTVERDGE 70
+ + +I ++ G+KI + FYP G GGQ GD+GKI G + V+ E++G
Sbjct: 1 MTAGRIRIDEVIKDGEKIIAVSRTSPFYPDGKGGQLGDRGKI-GPANVLKVK---EKNGY 56
Query: 71 IWHVGKLNGRTPEVGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRYDLDTSGFNIFGD 130
I H L+ E G+ E E+D R HT QHILSA K DL+T F++
Sbjct: 57 ILHY--LDAHL-EPGD-YECEIDPARRKDIACQHTAQHILSAAFLKVADLETVSFHMGER 112
Query: 131 YAKIEVNGELNWE-MIEEAELEANKVIIDDLPVRVEEYEVLPKGVVEKLR-KYIPNIKGK 188
+ I++N E ++EEAE AN+V+ V + E E K EK+ + +PN++GK
Sbjct: 113 VSTIDLNAPFVLEDVLEEAEDLANEVVRSCERVEILEIE---KEEAEKMNLRKLPNVEGK 169
Query: 189 IRIVRIGENFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFTCGFRAIKKLNEIL 248
+R+V+IG+ FD+T CGG HV++T E+G+IK++ K K RI FT G RA+K E
Sbjct: 170 VRVVKIGD-FDVTACGGFHVENTGEIGLIKIVDTEKVKKVLTRIYFTAGDRALKDYREKD 228
Query: 249 KDYWSALDAMPNKNPPLSERVREVLESVESLEEKVDSMRKEVWKWKE-ESLLGRSIEIGH 307
K S + L +R +LE V+ K+D + + K+ E S + ++G
Sbjct: 229 KLLKSLSRVLTTSTKELLKRAENLLEEVKEKSAKLDKLSE---KYAEILSKVAEPEKVGK 285
Query: 308 YNVVTFVEKWDIKDAQAFAVDFVKNNPGTIVVLASEDYVILARNEEVEVSMKSLLEDLIK 367
Y + F + + F+ + TIV+L D + + N + + + E L
Sbjct: 286 YYLYHFS---GTPEEMKYLPKFLADRKDTIVLLEHPDRIEIVSN---WIDCRKIFEKLKD 339
Query: 368 EFGGKGGGTDNLARGKIEAEPEDVIDFVVDRLREII 403
+ +GG + R I A I V++LREI+
Sbjct: 340 QLNVEGGSSQK--RAVITANSASRI---VEKLREIL 370
>sp|Q57984|SYA_METJA ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|2118343|pir||D64370 alanine--tRNA ligase (EC
6.1.1.7) - Methanococcus jannaschii
>gi|1591270|gb|AAB98556.1| (U67505) alanyl-tRNA
synthetase (alaS) [Methanococcus jannaschii]
Length = 892
Score = 130 bits (324), Expect = 3e-29
Identities = 107/417 (25%), Positives = 202/417 (47%), Gaps = 42/417 (10%)
Query: 5 LYYVDPYLKTAKAKISDLTIKGDKIEVSLTETIFYPRGGGQPGDKGKIRGDGFEIIVEDT 64
L+Y P +K +AKI L I D V L T FYP GGGQ D G I + V D
Sbjct: 495 LFYEYPKMKEFEAKI--LRIVDDY--VILDRTAFYPEGGGQKADTGYIIKGDKKFRVVDV 550
Query: 65 VERDGEIWH-VGKLNGRTPEVGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRYDLDT- 122
+ + ++H + LN E G+ V+ +DW+ R M+ HT HI++A +K
Sbjct: 551 QKENNIVYHKIENLNDELKE-GDIVKGVIDWKRRLSLMRNHTATHIINAAAQKVLGRHVW 609
Query: 123 -SGFNIFGDYAKIEVNG--ELNWEMIEEAELEANKVIIDDLPVR--------VEE---YE 168
+G ++ D A++++ ++ E +++ E AN++++++ ++ EE +
Sbjct: 610 QAGSDVDVDKARLDITHYKRISREELKDIERVANEIVLNNYNIKSIFMDRNEAEEKFGFR 669
Query: 169 VLPKGVVEKLRKYIPNIKGKIRIVRI----GENFDLTPCGGTHVKSTREVGVIKVLRFYK 224
+ GVV +RIV I G D+ CGGTH ++T EVG IK+++ +
Sbjct: 670 IYQGGVVPG---------NVLRIVIIEDENGNIVDVQACGGTHCQNTGEVGFIKIIKTER 720
Query: 225 KSKDTWRIEFTCGFRAIKKLNEILKDYWSALDAMPNKNPPLSERVREVLESVESLEEKVD 284
R+ ++ G A+K + E+ + + + L + ++ E + +K++
Sbjct: 721 VQDGVERLIYSSGLSALKAVQEMEDILEESAEILRCPTEELPKVIKRFFEEWKEQRKKIE 780
Query: 285 SMRKEVWKWKEESLLGRSIEIGHYNVVTFVEKWDIKDAQAFAV-DFVKNNPGTIVVLASE 343
+ K++ + K+ L+ + IG+Y V+ VEK + + + D + +V+L +
Sbjct: 781 ELEKKIGELKKFELINKFETIGNYKVL--VEKVEANPKEMLNIADNLATENAIVVLLNDK 838
Query: 344 DYVILARNEEVEVSMKSLLEDLIKEFGGKGGGTDNLARGKIEAEPEDVIDFVVDRLR 400
++ R E V++ M L+ + KGGG ++LA+GK E + E++ V++ ++
Sbjct: 839 GNILCKRGENVDIKMNELI-----RYIAKGGGREHLAQGKYEGDVEEIKKKVIEFIK 890
>pir||A75198 alanine--tRNA ligase truncated homolog PAB0066 - Pyrococcus abyssi
(strain Orsay) >gi|5457541|emb|CAB49032.1| (AJ248283)
fragment of ALANYL-TRNA SYNTHETASE [Pyrococcus abyssi]
Length = 213
Score = 127 bits (316), Expect = 2e-28
Identities = 85/241 (35%), Positives = 127/241 (52%), Gaps = 40/241 (16%)
Query: 1 MARKLYYVDPYLKTAKAKISDLTIKGDKIEVSLTETIFYPRGGGQPGDKGKIRGDGFEII 60
M RKLYY D YLK AKAK+ ++ + L +TIFYP GGGQP D+G I G +
Sbjct: 1 MTRKLYYEDAYLKEAKAKVVEIKDNA----LLLDQTIFYPTGGGQPHDRGTINGVEVLDV 56
Query: 61 VEDTVERDGEIWHVGKLNGRTPEVGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRYDL 120
+D +G +WHV K + +VG+EVEL++DW++RY M++HTG H+L VL
Sbjct: 57 YKD---EEGNVWHVVKEPEKF-KVGDEVELKIDWDYRYKLMRIHTGLHLLEHVLN----- 107
Query: 121 DTSGFNIFGDYAKIEVNGELNWEMIEEA-ELEANKVIIDDLPVRVEEYEVLPKGVVEKLR 179
EV GE WE++ +E + I P + +Y+ + ++
Sbjct: 108 --------------EVLGEGKWELVGSGMSVEKGRYDI-AYPENLNKYK---EQIISLFN 149
Query: 180 KYIPNIKGKIRIVRIGE-------NFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRI 232
KY+ G+++I GE +F++ PCGGTHVK +E+G IK L+ + R+
Sbjct: 150 KYVDE-GGEVKIWWEGETRYTQIRDFEVIPCGGTHVKDIKEIGHIKKLKRSSIGRGKQRL 208
Query: 233 E 233
E
Sbjct: 209 E 209
>gb|AAK40671.1| Alanyl-tRNA synthetase (alaS) [Sulfolobus solfataricus]
Length = 900
Score = 125 bits (312), Expect = 7e-28
Identities = 113/407 (27%), Positives = 194/407 (46%), Gaps = 31/407 (7%)
Query: 4 KLYYVDPYLKTAKAKISDLTIKGDKIEVSLTETIFYPRGGGQPGDKGKIRGDG----FEI 59
KLYY D Y+++ + K+ + K + L +T FYP GGGQ GD G I + +E+
Sbjct: 506 KLYYKDQYMRSFEGKVLGIY----KNYLILDKTTFYPEGGGQLGDTGLIIDEKSSKRYEV 561
Query: 60 IVEDTVERDGEIWHVGKLNGRTPEVGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRYD 119
+ DT + + I HV K T +VG+ V E++WE RY M+ HT H++ A KK
Sbjct: 562 V--DTQKVNDVIIHVLKEEPSTIKVGDNVRGEINWERRYRLMRHHTVTHVILAAAKKVLG 619
Query: 120 --LDTSGFNIFGDYAKIEVNGE--LNWEMIEEAELEANKVIIDDLPVR---VEEYEVLPK 172
+ +G + ++++ L E ++ E AN VI D PV+ + E K
Sbjct: 620 DHIWQAGAEKTPEKGRLDITHHKALTEEEVKLIENYANSVISDRRPVKPLEMNRMEAEMK 679
Query: 173 GVVEKLRKYIPNIKGKIRIVRIGENFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRI 232
V +PN IR++ I +++D+ CGGTHV +T E+G +K++ + R+
Sbjct: 680 YGVSIYEGGVPN-SATIRLLEI-KDWDIESCGGTHVSNTSEIGAVKIINVERIQDGIIRL 737
Query: 233 EFTCGFRAIKKLNEILKDYWSALDAMPNKNPPLSERVREVLESVESLEEKVDSMRKEVWK 292
E+ G + + E A + L R+R +L VE + R+ V
Sbjct: 738 EYVAGPALVDYIRETEAKIAEASKIIGTSPDQLPSRLRRILNEVEKKNNLIIQYRRIV-- 795
Query: 293 WKEESLLG--RSIEIGHYNVVTFVEKWDIKDAQAFAVDFVKNNPGTIVVLASEDYVILAR 350
E LL + EI + N + +E + ++ + + + TI + S++ + +A
Sbjct: 796 --ETELLNSLKPYEI-NGNKIYIIEGLNDEEENKEILRKLTSTDNTIAISISDNRLQIAT 852
Query: 351 NEEVEVSMKSLLEDLIKEFGGKGGGTDNLARGKIEAE--PEDVIDFV 395
++ + V ++E+L+K GGKGGG A + ++ E++ID V
Sbjct: 853 SKNMRVD--KIVEELLKG-GGKGGGKGTFANVILSSKKSKEEIIDIV 896
>pir||B71231 alanine--tRNA ligase truncated homolog PH0108 - Pyrococcus
horikoshii >gi|3256494|dbj|BAA29177.1| (AP000001) 216aa
long hypothetical alanyl-tRNA synthetase [Pyrococcus
horikoshii]
Length = 216
Score = 125 bits (311), Expect = 9e-28
Identities = 82/241 (34%), Positives = 127/241 (52%), Gaps = 40/241 (16%)
Query: 1 MARKLYYVDPYLKTAKAKISDLTIKGDKIEVSLTETIFYPRGGGQPGDKGKIRGDGFEII 60
M RKLYY D YLK AK ++ ++ + L +TIFYP GGGQP D+G I G +
Sbjct: 4 MTRKLYYEDAYLKEAKGRVLEIRDNA----ILLDQTIFYPTGGGQPHDRGTINGVEVLDV 59
Query: 61 VEDTVERDGEIWHVGKLNGRTPEVGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRYDL 120
+D +G +WHV K + +VG+EVEL++DW++RY M++HTG H+L VL
Sbjct: 60 YKD---EEGNVWHVVKEPEKF-KVGDEVELKIDWDYRYKLMRIHTGLHLLEHVLN----- 110
Query: 121 DTSGFNIFGDYAKIEVNGELNWEMIEEA-ELEANKVIIDDLPVRVEEYEVLPKGVVEKLR 179
EV GE NW+++ +E + I P + +Y+ + ++
Sbjct: 111 --------------EVLGEGNWQLVGSGMSVEKGRYDI-AYPENLNKYK---EQIISLFN 152
Query: 180 KYIPNIKGKIRIVRIGE-------NFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRI 232
KY+ G+++I G+ +F++ PCGGTHVK +E+G IK L+ + R+
Sbjct: 153 KYVDE-GGEVKIWWEGDRRYTQIRDFEVIPCGGTHVKDIKEIGHIKKLKRSSIGRGKQRL 211
Query: 233 E 233
E
Sbjct: 212 E 212
>sp|O67323|SYA_AQUAE ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|7437619|pir||H70411 alanine--tRNA ligase (EC
6.1.1.7) - Aquifex aeolicus >gi|2983727|gb|AAC07289.1|
(AE000733) alanyl-tRNA synthetase [Aquifex aeolicus]
Length = 867
Score = 120 bits (298), Expect = 3e-26
Identities = 117/406 (28%), Positives = 187/406 (45%), Gaps = 46/406 (11%)
Query: 25 KGDKIEVSLTETIFYPRGGGQPGDKGKIRGDGFEIIVEDTVE-RDGEIWHVGKLNGRTPE 83
+G++ EV L ET FYP GGGQ GD G I D VEDT + +G I H+GK+ T +
Sbjct: 479 EGEEGEVVLKETPFYPEGGGQIGDAGIIESDKALFKVEDTQKPTEGIIVHIGKVLKGTLK 538
Query: 84 VGEEVELELDWEWRYGNMQMHTGQHILSAVLKK--RYDLDTSGFNIFGDYAKIEVN--GE 139
VG+ V +D E R+ M+ HT H+L A L+ + +G + Y + +
Sbjct: 539 VGDTVHARVDKERRWDIMRNHTATHLLHAALRNVLGEHVRQAGSLVADKYLRFDFTHFSA 598
Query: 140 LNWEMIEEAELEANKVIIDDLPVRVEEY---EVLPKGVVEKLRKYIPNIKGKIRIVRIGE 196
L E ++ E N+ I ++LPV V E E L G + + ++R++ GE
Sbjct: 599 LTEEELKRVEELVNEKIRENLPVNVMEMAYDEALKTGAIAIFEE---KYGERVRVISCGE 655
Query: 197 NFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFTCGFRAIK---KLNEILKDYWS 253
F CGGTHV +T ++G K++ RI G +++ K ++ LK S
Sbjct: 656 -FSKELCGGTHVSATGDIGYFKIISESSVGAGVRRIVAQTGRWSVETAFKEHQTLKKASS 714
Query: 254 ALDAMPNKNPPLSERVREVLESVESLEEKVDSMRKEVWKWKEESLLGRSIEIG------- 306
AL EV++ +E L+E++ +E+ + K+E L + E+
Sbjct: 715 ALGV----------GEEEVIQKIEELKEEIKDREREIQRLKQELLKLQIREVVKEENVGD 764
Query: 307 ---HYNVVTFVEKWDIKDAQAFAVDFVKNNPGTIVVLASE--DYVILARNEEVEVSMKSL 361
HY V VE ++++ K + +V +AS D + E+S K
Sbjct: 765 FTLHYGVFEEVEPEELRNLADMLRQRTKKD---VVFIASRKGDKINFVIGVSKEISDKVN 821
Query: 362 LEDLIKEFG----GKGGGTDNLARGKIEAEPEDVIDFVVDRLREII 403
+++I+E G G GGG +LA+G +A D V L+EI+
Sbjct: 822 AKEVIREVGKVLKGGGGGRADLAQGGGKA--PDKFPEAVKLLKEIL 865
>sp|Q9XDM3|SYA_AQUPY ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|4587716|gb|AAD25871.1|AF027500_1 (AF027500)
alanyl-tRNA synthetase; alanine-tRNA ligase [Aquifex
pyrophilus]
Length = 871
Score = 118 bits (292), Expect = 1e-25
Identities = 113/397 (28%), Positives = 186/397 (46%), Gaps = 28/397 (7%)
Query: 25 KGDKIEVSLTETIFYPRGGGQPGDKGKIRGDGFEIIVEDTVE-RDGEIWHVGKLNGRTPE 83
+G++ E+ L ET FYP GGGQ GD G I D VEDT +G I H+GKL
Sbjct: 479 EGEEGEIILRETPFYPEGGGQIGDSGIIETDKGIFKVEDTQRPTEGIIVHIGKLLKGKIS 538
Query: 84 VGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRY--DLDTSGFNIFGDYAKIEVN--GE 139
V + V +D E R+ M+ HT H+L A L+ + +G + Y + +
Sbjct: 539 VKDIVHARVDKERRWDIMRNHTATHLLHAALRNLLGEHVRQAGSLVADKYLRFDFTHFSP 598
Query: 140 LNWEMIEEAELEANKVIIDDLPVRVEE---YEVLPKGVVEKLRKYIPNIKGKIRIVRIGE 196
L E I+ E N+ I ++LPV V E E L G + + ++R++ GE
Sbjct: 599 LTEEEIKRIEELVNEKIRENLPVSVMEMAYQEALQTGAIAIFEE---KYGERVRVISCGE 655
Query: 197 NFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFTCGFRAIKKLNEILKDYWSALD 256
F CGGTHV +T ++G K++ RI G A+ E +
Sbjct: 656 -FSKELCGGTHVSATGDIGYFKIISESSVGAGVRRIVAQTGRWAVNTAFEEHTTLKKVSN 714
Query: 257 AMPNKNPPLSERVREVLESVESLEEKVDSMRKEVWKW--KEESLLGRSIEIG-HYNVVTF 313
A+ K + ++V E+ E ++ E+++ +R+E+ K +E+ R E+ +Y V
Sbjct: 715 ALGVKEDEVVQKVEELKEEIKEKEKEIQKLRQEILKLQIREKVKEERHRELTLYYGVFED 774
Query: 314 VEKWDIKDAQAFAVDFVKNNPG-TIVVLASE-----DYVIL-ARNEEVEVSMKSLLEDLI 366
VE ++++ D ++ G +V +AS+ ++VI ++ EV L+ +
Sbjct: 775 VEPEELRN----LADILRQRTGKDVVFIASKKEGKINFVIASSKGISKEVRANELIRQVG 830
Query: 367 KEFGGKGGGTDNLARGKIEAEPEDVIDFVVDRLREII 403
K G GGG ++LA+G +A D D V L+E++
Sbjct: 831 KVLKGGGGGREDLAQGGGKA--PDKFDESVKLLKELL 865
>sp|Q9Y9X3|SYA_AERPE ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|7437623|pir||A72524 probable alanyl-tRNA synthetase
APE2166 - Aeropyrum pernix (strain K1)
>gi|5105865|dbj|BAA81177.1| (AP000063) 900aa long
hypothetical alanyl-tRNA synthetase [Aeropyrum pernix]
Length = 900
Score = 118 bits (292), Expect = 1e-25
Identities = 112/418 (26%), Positives = 196/418 (46%), Gaps = 25/418 (5%)
Query: 3 RKLYYVDPYLKTAKAKISDLTIKGDKIEVSLTETIFYPRGGGQPGDKGKIRGDGFEIIVE 62
R++++ DPY K KA++ L +KG + TIFYP GGGQ D G IR + + +
Sbjct: 491 RRVFHEDPYAKAWKARV--LGVKGRYLVAD--STIFYPTGGGQIHDTGVIRVNNQQYRII 546
Query: 63 DTVERDGEIWHVGKLNGRTPEVGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRYDLDT 122
D + I HV + E G+EV +E+DWE RY M+ HT H+L A ++
Sbjct: 547 DVQKVGDAIVHVAERE-IAAEPGDEVWMEIDWERRYSIMRHHTVTHVLIAAARRVLGRHA 605
Query: 123 --SGFNIFGDYAKIEVNGE--LNWEMIEEAELEANKVIIDDLPV---RVEEYEVLPKGVV 175
+G + ++++ L + IE+ E N+VI + V V++ E K
Sbjct: 606 WQAGAEKTEEKGRLDITHHRPLTRDDIEKLENVVNQVIRERRRVWEDMVDKNEAEEKYGF 665
Query: 176 EKLRKYIPNIKGKIRIVRIGENFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFT 235
+ +P K ++R+V + E++D+ C GTHV++T E+G K++ + + R+E+
Sbjct: 666 TIYQGGVPMEK-RLRLVFV-EDWDVEACFGTHVRNTGEIGGFKIISYSRIQDGVVRLEYV 723
Query: 236 CGFRAIKKLNEILKDYWSALDAMPNKNPPLSERVREVLESVESLEEKVDSMRKEVWKWKE 295
G R E+ + DA+ RV+ ++ S+E E + R K E
Sbjct: 724 AGDRVAIYARELEERLARIGDAVKAPRGQEEARVKGLIASLEQAREDLKRYRDYWVKTIE 783
Query: 296 ESLLGRSIEIGHYNV--VTFVEKWDIKDAQAFAVDFVKNNPGTIVVLASED----YVILA 349
E+ + R+ + V V +EK D + Q + I L E+ V +A
Sbjct: 784 EAYISRARRVNGVKVLAVESLEK-DRRTVQEILRKLTSRHEDLIAALVVENEGNTQVEIA 842
Query: 350 RNEEV--EVSMKSLLEDLIKEFGGKGGGTDNLARGKIEA--EPEDVIDFVVDRLREII 403
+ +V + +L++ +IK+ GG+GGG + A ++E + V + + D L ++
Sbjct: 843 AGPKAAEKVDLGALVKIVIKKVGGRGGGRGSYASLRVEGRLSADKVEELLADALENVL 900
>gb|AAA03208.1| (J01581) alanyl-tRNA synthetase [Escherichia coli]
Length = 876
Score = 113 bits (280), Expect = 4e-24
Identities = 94/375 (25%), Positives = 170/375 (45%), Gaps = 12/375 (3%)
Query: 18 KISDLTIKGDKIEVSLTETIFYPRGGGQPGDKGKIRGDGFEIIVEDTVERDGEIWHVGKL 77
K D G + V L +T FY GGQ GDKG+++G F VEDT + I H+GKL
Sbjct: 478 KAVDAINAGQEAVVVLDQTPFYAESGGQVGDKGELKGANFSFAVEDTQKYGQAIGHIGKL 537
Query: 78 NGRTPEVGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRYDLDTS--GFNIFGDYAKIE 135
+ +VG+ V+ ++D R H+ H++ A L++ S G + + +
Sbjct: 538 AAGSLKVGDAVQADVDEARRARIRLNHSATHLMHAALRQVLGTHVSHKGSLVNDKVLRFD 597
Query: 136 V--NGELNWEMIEEAELEANKVIIDDLPVRVEEYEVLPKGVVEKLRKYIPNIKGKIRIVR 193
N + E I E N +I +LP+ ++ + + ++R++
Sbjct: 598 FSHNEAMKPEEIRAVEDLVNTLIRRNLPIETNIMDLEAAKAKGAMALFGEKYDERVRVLS 657
Query: 194 IGENFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFTCGFRAIKKLNEILKDYWS 253
+G+ F CGGTH T ++G+ +++ + RIE G AI ++
Sbjct: 658 MGD-FSTELCGGTHASRTGDIGLFRIISESGTAAGVRRIEAVTGEGAIATVHADSDRLSE 716
Query: 254 ALDAMPNKNPPLSERVREVLESVESLEEKVDSMRKEVWKWKEESLLGRSIEIGHYNVVTF 313
+ + L+++VR VLE LE+++ ++++ + +L ++I++ ++
Sbjct: 717 VAHLLKGDSNNLADKVRSVLERTRQLEKELQQLKEQAAAQESANLSSKAIDVNGVKLLVS 776
Query: 314 VEKWDIKDAQAFAVDFVKNNPG-TIVVLAS--EDYVILARNEEVEVSMKSLLEDLI---- 366
VD +KN G TI+VLA+ E V L +V+ + +LI
Sbjct: 777 ELSGVEPKMLRTMVDDLKNQLGSTIIVLATVVEGKVSLIAGVSKDVTDRVKAGELIGMVA 836
Query: 367 KEFGGKGGGTDNLAR 381
++ GGKGGG ++A+
Sbjct: 837 QQVGGKGGGRPDMAQ 851
>sp|P00957|SYA_ECOLI ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|7428468|pir||SYECAT alanine--tRNA ligase (EC
6.1.1.7) [validated] - Escherichia coli
>gi|1789048|gb|AAC75739.1| (AE000353) alanyl-tRNA
synthetase [Escherichia coli K12]
>gi|1800083|dbj|BAA16559.1| (D90892) ALANYL-TRNA
SYNTHETASE (EC 6.1.1.7) (ALANINE--TRNA LIGASE) (ALARS).
[Escherichia coli]
Length = 876
Score = 112 bits (277), Expect = 8e-24
Identities = 94/375 (25%), Positives = 169/375 (45%), Gaps = 12/375 (3%)
Query: 18 KISDLTIKGDKIEVSLTETIFYPRGGGQPGDKGKIRGDGFEIIVEDTVERDGEIWHVGKL 77
K D G + V L +T FY GGQ GDKG+++G F VEDT + I H+GKL
Sbjct: 478 KAVDAINAGQEAVVVLDQTPFYAESGGQVGDKGELKGANFSFAVEDTQKYGQAIGHIGKL 537
Query: 78 NGRTPEVGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRYDLDTS--GFNIFGDYAKIE 135
+ +VG+ V+ ++D R H+ H++ A L++ S G + + +
Sbjct: 538 AAGSLKVGDAVQADVDEARRARIRLNHSATHLMHAALRQVLGTHVSQKGSLVNDKVLRFD 597
Query: 136 V--NGELNWEMIEEAELEANKVIIDDLPVRVEEYEVLPKGVVEKLRKYIPNIKGKIRIVR 193
N + E I E N I +LP+ ++ + + ++R++
Sbjct: 598 FSHNEAMKPEEIRAVEDLVNTQIRRNLPIETNIMDLEAAKAKGAMALFGEKYDERVRVLS 657
Query: 194 IGENFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFTCGFRAIKKLNEILKDYWS 253
+G+ F CGGTH T ++G+ +++ + RIE G AI ++
Sbjct: 658 MGD-FSTELCGGTHASRTGDIGLFRIISESGTAAGVRRIEAVTGEGAIATVHADSDRLSE 716
Query: 254 ALDAMPNKNPPLSERVREVLESVESLEEKVDSMRKEVWKWKEESLLGRSIEIGHYNVVTF 313
+ + L+++VR VLE LE+++ ++++ + +L ++I++ ++
Sbjct: 717 VAHLLKGDSNNLADKVRSVLERTRQLEKELQQLKEQAAAQESANLSSKAIDVNGVKLLVS 776
Query: 314 VEKWDIKDAQAFAVDFVKNNPG-TIVVLAS--EDYVILARNEEVEVSMKSLLEDLI---- 366
VD +KN G TI+VLA+ E V L +V+ + +LI
Sbjct: 777 ELSGVEPKMLRTMVDDLKNQLGSTIIVLATVVEGKVSLIAGVSKDVTDRVKAGELIGMVA 836
Query: 367 KEFGGKGGGTDNLAR 381
++ GGKGGG ++A+
Sbjct: 837 QQVGGKGGGRPDMAQ 851
>sp|Q9X1B6|SYA_THEMA ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|7437634|pir||E72259 alanine--tRNA ligase (EC
6.1.1.7) - Thermotoga maritima (strain MSB8)
>gi|4981959|gb|AAD36467.1|AE001792_7 (AE001792)
alanyl-tRNA synthetase [Thermotoga maritima]
Length = 863
Score = 110 bits (273), Expect = 2e-23
Identities = 110/390 (28%), Positives = 179/390 (45%), Gaps = 27/390 (6%)
Query: 29 IEVSLTETIFYPRGGGQPGDKGKIRGDGFEIIVEDTVER-DGEIWHVGKLNGRTPEVGEE 87
+EV + T FY GGQ D G + + +VE E +G I H K+ T G++
Sbjct: 485 VEVVFSRTPFYAEKGGQVSDTGMVEWRDGKALVEYVFEASEGVIVHRIKILDGTLRRGQK 544
Query: 88 VELELDWEWRYGNMQMHTGQHILSAVLKKRYD--LDTSGFNIFGDYAKIEVNG--ELNWE 143
V L +D + R M+ HT H+L A LKK + +G + D + + L+
Sbjct: 545 VILRVDKKRREATMRNHTATHLLHAALKKVLGDHVRQAGSLVAPDRLRFDFTHFKGLSSA 604
Query: 144 MIEEAELEANKVIIDDLPVRVEEY---EVLPKGVVEKLRKYIPNIKGKIRIVRI-GENFD 199
IE+ E N+ I++ +PV V E + GVV + ++ +R+V + G + +
Sbjct: 605 EIEQVEDLVNEWIMEAIPVEVRYTSYEEAVKSGVVALFTEKYGDV---VRVVEVPGVSKE 661
Query: 200 LTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFTCGFRAIKKLNEILKDYWSALDAMP 259
L CGGTHVK+T ++G+ K++ S RIE GF A++ L K + +
Sbjct: 662 L--CGGTHVKNTGQIGLFKIISEESVSSGVRRIEAVTGFSALELLRNQKKLIDQLKEILG 719
Query: 260 NKNPPLSERVREVLESVESLEEKVDSMRKEVWKWKEESLLGRSIEIGHYNVVTFVEKWDI 319
+ L++RV + E V+ LE+K+ R EE + + +E G E +
Sbjct: 720 AREDELTDRVLSLREKVKELEKKLSQGR-----ISEERIAMKQLEDGVKVFHGVFEGVEA 774
Query: 320 KDAQAFAVDFVKNNPGTIVVLASED------YVILARNEEVEVSMKSLLEDLIKEFGGKG 373
K A + +K IV+L S+ V ++ N + S+ ++ KE GG G
Sbjct: 775 KHLGGIADNVLKKEGEGIVILFSKFENKVSLVVKVSENLLGKYDASSIARNIAKELGGNG 834
Query: 374 GGTDNLARGKIEAEPEDVIDFVVDRLREII 403
GG N A+ PE + D V++RL E +
Sbjct: 835 GGRKNFAQAG-GRHPERIKD-VLERLEEFL 862
>sp|P74423|SYA_SYNY3 ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|7437614|pir||S76394 hypothetical protein -
Synechocystis sp. (strain PCC 6803)
>gi|1653611|dbj|BAA18523.1| (D90915) alanyl-tRNA
synthetase [Synechocystis sp.]
Length = 877
Score = 109 bits (271), Expect = 4e-23
Identities = 89/388 (22%), Positives = 170/388 (42%), Gaps = 35/388 (9%)
Query: 18 KISDLTIKGDKIEVSLTETIFYPRGGGQPGDKGKIRGDGFEIIVEDTVERDGEIWHVGKL 77
++ D + G +++ L +T FY GGQ GDKG + GD I +ED G H G++
Sbjct: 476 ELVDQAVAGQTVQIVLDQTPFYGESGGQIGDKGFLNGDNLLIRIEDVKRESGIFIHFGRV 535
Query: 78 NGRTPEVGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRYDLDTSGFNIFGDYAKIEVN 137
T ++G + +D R HT H+L + LK+ D S D+ ++ +
Sbjct: 536 ERGTVQIGTTITATIDRACRRRAQANHTATHLLQSALKRVVDEGISQAGSLVDFNRLRFD 595
Query: 138 ----GELNWEMIEEAELEANKVIIDDLPVRVEEYEVLPKGVVEKLRKYIPNIKGKIRIVR 193
+ E +++ E N+ I + V + + + ++R++
Sbjct: 596 FNSPRAVTMEELQQIEDLINQWIAEAHQTEVAVMPIADAKAKGAIAMFGEKYGAEVRVID 655
Query: 194 IGENFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFTCGFRAIKKLN---EILKD 250
+ L CGGTHV +T E+G+ K++ + RIE G + LN ++K+
Sbjct: 656 V-PGVSLELCGGTHVANTAEIGLFKIVAETGIAAGVRRIEAVAGPSVLDYLNVREAVVKE 714
Query: 251 YWSALDAMPNKNPPLSERVREVLESVESLEEKVDSMRKEVWKWKEESLLGRSIEIGHYNV 310
L A P + P +RV ++ + +++ +++++++++E+ K E LL ++ +G + +
Sbjct: 715 LGDRLKAKPEEIP---DRVHQLQQELKASQKQLEALKQELALQKSEQLLTQAQTVGEFKI 771
Query: 311 VTFVEKWDIKDAQAFAVDFVKNNPGTIVVLASEDYVILAR-NEEVEVSMKS--------- 360
+ + D + +K + E V+LA EE +VS+ +
Sbjct: 772 L-------VADLGTVDGESLKTAAERLQQKLGESAVVLASIPEEGKVSLVAAFSPQLVKT 824
Query: 361 -------LLEDLIKEFGGKGGGTDNLAR 381
+ + K GG GGG NLA+
Sbjct: 825 KQLKAGQFIGAIAKICGGGGGGRPNLAQ 852
>gb|AAG20397.1| (AE005112) alanyl-tRNA synthetase; AlaS [Halobacterium sp. NRC-1]
Length = 929
Score = 109 bits (271), Expect = 4e-23
Identities = 109/420 (25%), Positives = 190/420 (44%), Gaps = 34/420 (8%)
Query: 5 LYYVDPYLKTAKAKISDLTIK----GD-KIEVSLTETIFYPRGGGQPGDKGKIRGDGFEI 59
LYY D Y +A + D+ + GD +V L +T+FYP GGGQP D G + GD +
Sbjct: 518 LYYDDAYGSEFEAVVLDVFEREGEDGDGAFDVVLDQTMFYPEGGGQPADTGVLTGDDHTV 577
Query: 60 IVEDTVERDGEIWHVGKLNGRTPEVGEEVELELDWEWRYGNMQMHTGQHILSAVLKK--R 117
V D ERDG + H N P GE V ++D E R M HT HI+ ++
Sbjct: 578 DVIDVQERDGVVLHRTTDN---PGKGEFVRGQIDTERRRRLMAHHTATHIVVYAARQVLG 634
Query: 118 YDLDTSGFNIFGDYAKIEVN--GELNWEMIEEAELEANKVIIDDLPVRVE---EYEVLPK 172
+ +G D ++I+V ++ E ++E E AN+++ + V+ E +E +
Sbjct: 635 EHVRQAGAQKGVDSSRIDVTHYERVDRETVKEIERVANEIVRANTSVQCEWPDRHEAEAE 694
Query: 173 GVVEKLRKYIPNIKGKIRIVRIGENFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRI 232
+ + IP +IR+V + + D+ CGGTHV T E+G IK+L + R+
Sbjct: 695 YGFDLYQGGIP-AGEQIRLVHVDD--DVQACGGTHVARTGEIGSIKILNAERVQDGVERL 751
Query: 233 EFTCGFRAIKKL---NEILKDYWSALDAMPNKNPPLSERV----REVLESVESLEEKVDS 285
F G A++ + + L+ LD P + P +ER ++ ++++ L+E++
Sbjct: 752 TFAAGAAAVEHVQGQEDDLRAAAEVLDVTPAEVPETAERFFTEWKDRGKTIDDLKEQLAE 811
Query: 286 MRKEVWKWKEESLLGRSIEIGHYNVVTFVEKWDIKDAQAFAVDFVKNNPGTIVVLASED- 344
R G +++ V D+ + QA A V +V ++
Sbjct: 812 AR------ASGGGAGEEVDVAGTTAVVQRVDGDMDELQATANALVDGGQVAVVGSGADGA 865
Query: 345 YVILARNEEVEVSMKSLLEDLIKEFGGKGGGTDNLARGKIEAEPEDVIDFVVDRLREIIG 404
++ + V V+ ++ +L GG GGG + A+G + +D + R +++G
Sbjct: 866 QFVVGVPDGVPVNAGEVVGELAAMVGGGGGGPPDFAQG--GGPDAERLDDALSRAADVLG 923
>gi|6324288 Ynl040wp [Saccharomyces cerevisiae]
>gi|1730724|sp|P53960|YNE0_YEAST HYPOTHETICAL 51.0 KD
PROTEIN IN YIP3-TFC5 INTERGENIC REGION
>gi|2131872|pir||S62962 hypothetical protein YNL040w -
yeast (Saccharomyces cerevisiae)
>gi|1301892|emb|CAA95907.1| (Z71316) ORF YNL040w
[Saccharomyces cerevisiae]
Length = 456
Score = 108 bits (268), Expect = 1e-22
Identities = 104/398 (26%), Positives = 172/398 (43%), Gaps = 52/398 (13%)
Query: 30 EVSLTETIFYPRGGGQPGDKGKIR-------GDGFEIIVEDTVERDGEIWHVGKLNGRTP 82
E+ L +TI +P GGGQP D G ++ E I+ V R G H
Sbjct: 46 EIELQDTILFPEGGGQPSDSGFLKIVEGNRNSSKIEKILVSHVSRFG--LHAKHHVNDYI 103
Query: 83 EVGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRYDLDTSGFNIFGDYAK--------- 133
E G VE+ +D + R MQ HTGQH+LSA+L++ Y +DT +++ G K
Sbjct: 104 EPGTTVEVAVDEQKRMDYMQQHTGQHLLSAILERNYKVDTVSWSMGGIITKKKPVLEPSD 163
Query: 134 ----IEVNGELNWEMIEEAELEANKVIIDDLPVRVEEYEVLPKGVVEKLRKYIPN----I 185
IE+N +L + I E N++II+ + E + + V E IP+
Sbjct: 164 YFNYIELNRKLTLDEITNVSDEINQLIINFPQEIIVEERIGEETVDEVSTSKIPDDYDLS 223
Query: 186 KGKIRIVRIGENFDLTPCGGTHVKSTREVGVIKVLRFYKKSK-DTWRIEFTCGFRA---I 241
KG +R + IG+ D PC GTH+K T ++G I +L + R+ F CG R
Sbjct: 224 KGVLRTIHIGD-IDSNPCCGTHLKCTSQIGSILILSNQSAVRGSNSRLYFMCGKRVSLYA 282
Query: 242 KKLNEILKDYWSALDAMPNKNPPLSERVREVLESVESLEEKVDSMRKEVWKWKEESLLGR 301
K +N+IL D + L + +SE++ + ++ L ++ K + + E L+
Sbjct: 283 KSVNKILLDSKNLLSCSETQ---ISEKITRQTKQIQQLNKREQYWIKRLARTASEELMNT 339
Query: 302 SIEIGHYNVVTFVEKWDI--------KDAQAFAVDFVKNNPGTIVVLASED-------YV 346
G E++ K+ F D + G ++L + +
Sbjct: 340 LKASGKKRAYFMEEEYGTLELLLQIHKEVSNFLKD---DTEGYEIILCGYERQTNTGSLL 396
Query: 347 ILARNEEVEVSMKSLLEDLIKEFGGKGGGTDNLARGKI 384
IL+ + E ++ + L +++ G GG +GKI
Sbjct: 397 ILSESGEKIANLAANLGSILQNLKGGGGKKGGKWQGKI 434
>sp|O34526|SYA_BACSU ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|7437617|pir||A69584 alanine--tRNA ligase (EC
6.1.1.7) alaS - Bacillus subtilis
>gi|2635186|emb|CAB14682.1| (Z99117) alanyl-tRNA
synthetase [Bacillus subtilis]
>gi|2635204|emb|CAB14699.1| (Z99118) alanyl-tRNA
synthetase [Bacillus subtilis]
Length = 878
Score = 106 bits (261), Expect = 6e-22
Identities = 94/401 (23%), Positives = 189/401 (46%), Gaps = 30/401 (7%)
Query: 25 KGDKIEVSLTETIFYPRGGGQPGDKGKIRGDGFEIIVEDTVER-DGEIWHVGKLNGRTPE 83
+G+ +++ L ET FY GGQ GDKG +R + + ++D + +G+ H G + T +
Sbjct: 486 EGESVQIILDETPFYAESGGQIGDKGYLRSEQAVVRIKDVQKAPNGQHVHEGVVESGTVQ 545
Query: 84 VGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRYD--LDTSGFNIFGDYAKIEVN--GE 139
G V E++ R G ++ HT H+L LK ++ +G + + + + + G+
Sbjct: 546 KGLHVTAEVEDHMRSGVIKNHTATHLLHQALKDVLGTHVNQAGSLVTENRLRFDFSHFGQ 605
Query: 140 LNWEMIEEAELEANKVIIDDLPVRVEEYEVLPKGVVEKLRKYIPNIKGKIRIVRIGENFD 199
+ E +E+ E N+ I +PV ++ + + + + +R+V++G+ +
Sbjct: 606 VTKEELEQIERIVNEKIWASIPVSIDLKPIAEAKEMGAMALFGEKYGDIVRVVQVGD-YS 664
Query: 200 LTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFTCGFRAIKKLNEILKDYWSALDAMP 259
L CGG HV++T E+G+ K++ T RIE G A ++N + D +
Sbjct: 665 LELCGGCHVRNTAEIGLFKIVSESGIGAGTRRIEAVTGQGAYVEMNSQISVLKQTADELK 724
Query: 260 NKNPPLSERVREVLESVESLEEKVDSMRKEVWKWKEESLLGRSIEIGHYNVVTFVEKWDI 319
+ +RV + ++ + + +S+ ++ + ++L + E+ NV+ K +
Sbjct: 725 TNIKEVPKRVAALQAELKDAQRENESLLAKLGNVEAGAILSKVKEVDGVNVL--AAKVNA 782
Query: 320 KDAQAF--AVDFVKNNPGTIVVLASEDYVILARNEEVEVS---MKSLLE------DLIKE 368
KD VD +K G+ V++ +N++V +S K L+E L+K+
Sbjct: 783 KDMNHLRTMVDELKAKLGSAVIVLG-----AVQNDKVNISAGVTKDLIEKGLHAGKLVKQ 837
Query: 369 ----FGGKGGGTDNLAR--GKIEAEPEDVIDFVVDRLREII 403
GG GGG ++A+ GK + E+ + V D ++ ++
Sbjct: 838 AAEVCGGGGGGRPDMAQAGGKQPEKLEEALASVEDWVKSVL 878
>pir||H83533 alanyl-tRNA synthetase PA0903 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9946804|gb|AAG04292.1|AE004524_9
(AE004524) alanyl-tRNA synthetase [Pseudomonas
aeruginosa]
Length = 874
Score = 106 bits (261), Expect = 6e-22
Identities = 94/383 (24%), Positives = 170/383 (43%), Gaps = 39/383 (10%)
Query: 25 KGDKIEVSLTETIFYPRGGGQPGDKGKIRGDGFEIIVEDTVERDGEIWHVGKLNGRTPEV 84
+G++ V L +T FY GGQ GD G + G V DT + G H G + V
Sbjct: 483 EGEEGVVVLDQTPFYAESGGQVGDSGYLEAAGVRFDVRDTTKAGGAHLHHGVVARGNLSV 542
Query: 85 GEEVELELDWEWRYGNMQMHTGQHILSAVLKKRYDLDTSGFNIFGDYAKIEVNGEL---- 140
G V+ E+D R H+ H+L A L++ + GD+ ++ G L
Sbjct: 543 GGAVKAEVDASVRQATALNHSATHLLHAALRQ----------VLGDH--VQQKGSLVDSQ 590
Query: 141 -------NWEMIEEAELEANKVIID-----DLPVRVEEYEVLPKGVVEKLRKYIPNIKGK 188
++E I+ +L+A + I++ + V EE ++ + + +
Sbjct: 591 RLRFDFSHFEAIKAEQLKALEDIVNAEIRRNTEVETEETDIDTAKAKGAMALFGEKYGDQ 650
Query: 189 IRIVRIGENFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFTCGFRAIKKLNEIL 248
+R++ +G +F + CGGTHV T ++G+ K+ + RIE G A+ LN
Sbjct: 651 VRVLSMGGDFSVELCGGTHVSRTGDIGLFKITSEGGVAAGVRRIEAVTGAAALAYLNGAE 710
Query: 249 KDYWSALDAMPNKNPPLSERVREVLESVESLEEKVDSMRKEVWKWKEESLLGRSIEIGHY 308
+ A + L +++ +LE SLE++++ ++ + + L ++EI
Sbjct: 711 EQLKEAASLVKGSRDNLLDKLGALLERNRSLEKELEQLKAKAASAAGDDLSAAAVEIKGA 770
Query: 309 NVVTFVEKWDIKDAQAF--AVDFVKNNPGTIVVLAS---EDYVILARNEEVEVSMKSLLE 363
V+ + D D +A VD +KN G V+L + V+L +++ +
Sbjct: 771 KVL--AARLDGLDGKALLALVDQLKNKLGRAVILLGGELDGKVVLVAGVTQDLTGQLKAG 828
Query: 364 DLIKE----FGGKGGGTDNLARG 382
+L+K+ GGKGGG ++A+G
Sbjct: 829 ELMKQAAAAVGGKGGGRPDMAQG 851
>dbj|BAB06653.1| (AP001517) unknown conserved protein in others [Bacillus
halodurans]
Length = 242
Score = 106 bits (261), Expect = 6e-22
Identities = 73/239 (30%), Positives = 120/239 (49%), Gaps = 12/239 (5%)
Query: 1 MARKLYYVDPYLKTAKAKISDLTIKGDKIEVSLTETIFYPRGGGQPGDKGKIRGDGFEII 60
M+++LY D Y + + + L +K +V L ETIF+P GGGQP D+G + +G
Sbjct: 1 MSKELYLEDSYRQDYTSNVKLL----NKDKVILEETIFHPNGGGQPNDEGWLYQNGKAYK 56
Query: 61 VEDTVERDGEIWHVGKLNGRTPEVGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRYDL 120
V + + EI H L +EV ++++W RY M+ HT H+++ L Y
Sbjct: 57 VINVRKEGEEIIHY--LEDADDLEEDEVRMKINWSRRYNFMKYHTLLHLVAGHLYHEYGA 114
Query: 121 DTSGFNIFGDYAKIEVN---GELNWEMIEEAELEANKVIIDDLPVRVEEYEVLPKGVVEK 177
G IF + A+++++ GEL+ + E E N++I + + + E + + EK
Sbjct: 115 LAIGNQIFENRARLDIDFRGGELDVDF-HRVEEELNRLINEGRKMNIRNVERDSESISEK 173
Query: 178 LRKYIPNIKGKIRIVRIG--ENFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEF 234
+R I I ++ +R+ EN D PC GTHV + E+G K+ K K R+EF
Sbjct: 174 IRTVINLIPASVKNIRLVAIENMDEQPCSGTHVNNINEIGPFKISGNKSKGKGKRRLEF 232
>emb|CAC11271.1| (AL445063) alanyl-tRNA synthetase related protein [Thermoplasma
acidophilum]
Length = 245
Score = 105 bits (259), Expect = 1e-21
Identities = 78/244 (31%), Positives = 125/244 (50%), Gaps = 18/244 (7%)
Query: 1 MARKLYYVDPYLKTAKAKISDLTIKGDKIEVSLTETIFYPRGGGQPGDKGKIRGDGFEII 60
+ KLYY D Y+K +A++ + G + L T FYP GGGQP D G I D
Sbjct: 5 VTEKLYYDDMYMKEFQAEVVSVDSNG----IVLDRTAFYPTGGGQPNDTGIIVNDDKTYR 60
Query: 61 VEDTVERDGEIWHV-GKLNGRTPEVGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRYD 119
V D + ++ H+ ++G + G+ + ++DWE RY +M+ HT HIL ++ +++
Sbjct: 61 VVDVQKHGDDVVHILESVDGL--KAGDRIYGKIDWERRYAHMRYHTAIHILDGIVSAKHN 118
Query: 120 LDT--SGFNIFGDYAKIEVNGE-LNWEMIEEAELEANKVIIDDLPVRVEEY---EVLPK- 172
+ +G I+ D ++I++N E E +++ EAN+ I + V E E + +
Sbjct: 119 SEALLTGGQIYEDRSRIDMNIENFTKEFVDQIIQEANEFISEGHRVYAENISREEAMKRP 178
Query: 173 --GVVEKLRKYIPNIKGKIRIVRIGENFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTW 230
E RK I ++ +RI+ I E D GGTHV +TREVG I + + K +
Sbjct: 179 NLARTEPGRKLIESLP-VVRIIVI-EGLDEQSDGGTHVANTREVGKIVLRKIENKGRKNK 236
Query: 231 RIEF 234
RIEF
Sbjct: 237 RIEF 240
>sp|P57483|SYA_BUCAI ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|10039072|dbj|BAB13106.1| (AP001119) alanyl-tRNA
synthetase [Buchnera sp. APS]
Length = 878
Score = 101 bits (248), Expect = 2e-20
Identities = 90/373 (24%), Positives = 167/373 (44%), Gaps = 18/373 (4%)
Query: 24 IKGDKIEVSLTETIFYPRGGGQPGDKGKIRGDGFEIIVEDTVERDGEIWHVGKLNGRTPE 83
IK +K + L +T FY GGQ GD G++ +VE T + I H+GKL
Sbjct: 484 IKDEKGVIFLDKTPFYSESGGQIGDIGQLYHKKSSFLVEKTKKYGKTIGHIGKLISGQIT 543
Query: 84 VGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRY--DLDTSGFNIFGDYAKIEVN--GE 139
+ + + +D ++RY H+ H+L A L+K + G + Y + + +
Sbjct: 544 LNDSLFSHIDEDYRYAIQLNHSATHLLHATLRKILGDSIVQKGSLVTNTYLRFDFSYVKS 603
Query: 140 LNWEMIEEAELEANKVIIDDLPVRVEEYEVLPKGVVEKLRKYIPNIKGKIRIVRIGENFD 199
++ I++ E N I +++ ++ EE L + +K + G I V NF
Sbjct: 604 IDTSQIQKIENIINTNIRNNIKIKTEELN-LEEAKKKKAMALFDDQYGSIVRVVFINNFS 662
Query: 200 LTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFTCGFRAIKKLNE---ILKDYWSALD 256
+ CGGTH + T ++G+ K++ + RIE G +AI L+E +KD L+
Sbjct: 663 IELCGGTHTQRTGDIGLFKIISQSSVASGIKRIEAVTGQKAIDYLHEKDNYIKDISLLLN 722
Query: 257 AMPNKNPPLSERVREVLESVESLEEKVDSMRKEVWKWKEESLLGRSIEIGHYNVVTFV-E 315
+ E+ +++ ++LE+K+ ++K+ + +L EI ++T +
Sbjct: 723 C---STVDIKEKTKKLTIKTKNLEKKIIQLQKKENTQYIKKILKNVTEIKGTKLLTNIFY 779
Query: 316 KWDIKDAQAFAVDFVKNNPGTIVVLAS------EDYVILARNEEVEVSMKSLLEDLIKEF 369
++ K + K TI++L + V + RN ++ ++E +I +
Sbjct: 780 DYEQKSLRMIVDQLKKELKNTIIILINIINNRFTIIVGVTRNLLDYITAIKIMEMIINKT 839
Query: 370 GGKGGGTDNLARG 382
GKGGG +A G
Sbjct: 840 NGKGGGKKEIAEG 852
>dbj|BAB04986.1| (AP001511) alanyl-tRNA synthetase [Bacillus halodurans]
Length = 879
Score = 100 bits (247), Expect = 3e-20
Identities = 96/402 (23%), Positives = 185/402 (45%), Gaps = 21/402 (5%)
Query: 19 ISDLTIKGDKIEVSLTETIFYPRGGGQPGDKGKIRG-DGFEIIVEDTVERDGEIWHVGKL 77
++D G + +V L ET FY GGQ DKG IRG +GF ++ + +G+ H +
Sbjct: 480 VADYVGAGQEAKVILKETPFYAESGGQVADKGIIRGANGFAVVSDVQKAPNGQHLHTVIV 539
Query: 78 NGRTPEVGEEVELELDWEWRYGNMQMHTGQHILSAVLKK--RYDLDTSGFNIFGDYAKIE 135
T +V ++V+ ++ R G ++ HT H+L LK ++ +G + + + +
Sbjct: 540 KEGTLQVNDQVQAIVEETERSGIVKNHTATHLLHRALKDVLGEHVNQAGSLVSEERLRFD 599
Query: 136 VN--GELNWEMIEEAELEANKVIIDDLPVRVEEYEVLPKGVVEKLRKYIPNIKGKIRIVR 193
+ G++ E E+ E N+ I + V + + + + + +R+V
Sbjct: 600 FSHFGQVTDEEKEKIERIVNEKIWQAIKVNISTKTLDEAKAIGAMALFGEKYGDIVRVVE 659
Query: 194 IGENFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFTCG---FRAIKKLNEILKD 250
+G+ + + CGG HV +T E+G+ K++ RIE G F + K ++LK+
Sbjct: 660 VGD-YSIELCGGCHVTNTSEIGLFKIVSESGIGAGVRRIEAVTGKEAFLFMAKQLDLLKE 718
Query: 251 YWSALDAMPNKNPPLSERVREVLESVESLEEKVDSMRKEVWKWKEESLLGRSIEIGHYNV 310
+ + A K+ P+ RV + + + L+ + +S+ ++ + SL+ +I V
Sbjct: 719 TAATVKAKNVKDVPV--RVEALQQQIRELQRENESLNAKLGNMEAGSLVNEVQKIEGVPV 776
Query: 311 VTFVEKWDIKDAQAFAVDFVKNN-PGTIVVL--ASEDYVILARNEEVEVSMK-----SLL 362
+ D VD +K P ++VL ASE V + ++ K L+
Sbjct: 777 LAKAISGADMDGLRSIVDKLKQEIPSVVIVLGTASEGKVNIVAGVTKDLINKGYHAGKLV 836
Query: 363 EDLIKEFGGKGGGTDNLAR--GKIEAEPEDVIDFVVDRLREI 402
+++ GG GGG ++A+ GK + +D + FV + ++ I
Sbjct: 837 KEVATRCGGGGGGRPDMAQAGGKQPEKLQDALSFVYEYVKSI 878
>pir||A83382 hypothetical protein PA2106 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9948120|gb|AAG05494.1|AE004638_4
(AE004638) hypothetical protein [Pseudomonas aeruginosa]
Length = 244
Score = 100 bits (246), Expect = 4e-20
Identities = 81/251 (32%), Positives = 127/251 (50%), Gaps = 31/251 (12%)
Query: 5 LYYVDPYLKTAKAKISDLTIKGDKIEVSLTETIFYPRGGGQPGDKGKIR-GDGFEIIVED 63
L+ D Y + A+I+D+ G + L +T+FYP+GGGQ GD G + DG + + D
Sbjct: 7 LFLQDSYREECLARITDVVEDG----LLLDQTVFYPQGGGQAGDSGWLTLADGTRLRIAD 62
Query: 64 TVE-------RDGEIWHVGKLNG----RTPEVGEEVELELDWEWRYGNMQMHTGQHILSA 112
T + RD I H+ R + GE V ++DW RY +M++HT H+L A
Sbjct: 63 TRKGTEAGAGRDA-ILHIPAEGQATVLRAMKPGEVVLAQIDWVRRYRHMRLHTAAHMLCA 121
Query: 113 VLKKRYDLDTSGFNIFGDYAKIE--VNGELNWEMIEEAELE----ANKVIIDDLPVRVEE 166
VL +G +I ++A+++ + L+ E I+ A A+ V ID + ++
Sbjct: 122 VLP----YPVNGCSITDEHARLDFVTSEPLSREAIDSALAAMVEAAHPVSIDTMS---DD 174
Query: 167 YEVLPKGVVEKLRKYIPNIKGKIRIVRIGENFDLTPCGGTHVKSTREVGVIKVLRFYKKS 226
+V + P G++R+V I + DL PCGGTHV +T EVGV++V + KKS
Sbjct: 175 ALRARPDLVRTMSVQPPMGAGQVRLVSIKDT-DLQPCGGTHVANTEEVGVVRVSKMEKKS 233
Query: 227 KDTWRIEFTCG 237
T R+ G
Sbjct: 234 ARTRRVVLVLG 244
>gb|AAK40776.1| Alanyl-tRNA synthetase truncated homolog (alaS-like1) [Sulfolobus
solfataricus]
Length = 236
Score = 99.8 bits (245), Expect = 5e-20
Identities = 80/242 (33%), Positives = 127/242 (52%), Gaps = 16/242 (6%)
Query: 1 MARKLYYVDPYLKTAKAKISDLTIKGDKIEVSLTETIFYPRGGGQPGDKGKIRGDGFEII 60
M +LY D Y+K + ++ + I+G+ V L +T FYP GGG D G + + E I
Sbjct: 1 MTEELYLKDSYIKEFEGRV--VRIEGNY--VILDKTAFYPGGGGLDNDTGFLVNEKGERI 56
Query: 61 VEDTVER--DGEIWHVGKLNGRTPEVGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRY 118
V+R +GEI H NG V E+V +DW+ RY M++HT HI++A+ +++
Sbjct: 57 SVTEVKRGENGEILHKIDQNGSL-NVNEKVIGTIDWDRRYRMMRLHTASHIVAALAYRKF 115
Query: 119 DLDTSGFNIFGDYAKIEVNGELNWEMIEEAELEANKVIIDDLPVRV-----EEYEVLPKG 173
+G +I + AK + N E N + + E EAN++I D+ +++ EE ++P
Sbjct: 116 GALITGGHISPEQAKDDFNVE-NKDTLIELINEANEIIKKDIELKIYFLPREEALMIP-- 172
Query: 174 VVEKLRKYIPNIKGKIRIVRIGENFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIE 233
+ KL P RIV I D+ GG HVK+T+E+G I +L+ K K R+
Sbjct: 173 AIVKLAGRNPPQIPIWRIVEI-PGIDIQADGGPHVKNTKEIGEIVLLKVENKGKGRKRVY 231
Query: 234 FT 235
+T
Sbjct: 232 YT 233
>sp|P43815|SYA_HAEIN ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|1073831|pir||I64095 alanine--tRNA ligase (EC
6.1.1.7) - Haemophilus influenzae (strain Rd KW20)
>gi|1573826|gb|AAC22473.1| (U32763) alanyl-tRNA
synthetase (alaS) [Haemophilus influenzae Rd]
Length = 874
Score = 99.8 bits (245), Expect = 5e-20
Identities = 86/389 (22%), Positives = 175/389 (44%), Gaps = 27/389 (6%)
Query: 15 AKAKISDLTIKGDKIE---------VSLTETIFYPRGGGQPGDKGKIRGDGFEIIVEDTV 65
++AKI+ L G +E V L T FY GGQ GD G + V+DT
Sbjct: 465 SQAKITALFYDGKSVESIEAGQSAVVILENTPFYAESGGQIGDSGYLSTQSVTFNVKDTQ 524
Query: 66 ERDGEIWHVGKLNGRTPEVGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRYDLD---- 121
+ H+G+L + +VG+ V +D + R+ H+ H+L A L++ L
Sbjct: 525 KYGQVFGHIGELTQGSLKVGQSVNAIVDAKRRHNTSLNHSATHLLHAALRQILGLHVVQK 584
Query: 122 ---TSGFNIFGDYAKIEVNGELNWEMIEEAELEANKVIIDDLPVRVEEYEVLPKGVVEKL 178
S + D+A+ E + E + E E N+ I + PV+ + ++ +
Sbjct: 585 GSLVSDKALRFDFAQPEA---ITKEQLSEIETLVNQKIRANFPVQTDIMDIDSAKAKGAM 641
Query: 179 RKYIPNIKGKIRIVRIGENFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFTCGF 238
+ K+R++ +G+ F + CGG H K T ++G+ K++ + RIE G
Sbjct: 642 ALFGEKYGDKVRVLTMGD-FSIELCGGIHAKRTGDIGLFKIITENAVAAGIRRIEAVTGQ 700
Query: 239 RAIKKLNEILKDYWSALDAMPNKNPPLSERVREVLESVESLEEKVDSMRKEVWKWKEESL 298
AI L+ + + D + + L+E+++++ + + +E+++ ++++
Sbjct: 701 NAIDWLHNQQRILTQSADLLKSDVNTLAEKIQQLQDKAKKVEKELQGLKEKAAMQAGSYF 760
Query: 299 LGRSIEIGHYNVVTFVEKWDIKDAQAFAVDFVKNNPGTIV-----VLASEDYVILARNEE 353
+ +++I +V+ + VD +KN G+ V +L + +++ +
Sbjct: 761 VKSAVKINGVSVIAQQLDGIETKSLRVMVDDLKNQLGSGVIAFASILDEKVNLVVGVTND 820
Query: 354 VEVSMKS--LLEDLIKEFGGKGGGTDNLA 380
+ +K+ L+ + ++ GGKGGG ++A
Sbjct: 821 LTAKIKAGELVNLMAQQVGGKGGGRPDMA 849
>sp|Q56273|SYA_THIFE ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|1263913|emb|CAA64818.1| (X95571) alanyl-tRNA
synthetase [Thiobacillus ferrooxidans]
Length = 877
Score = 94.4 bits (231), Expect = 2e-18
Identities = 89/380 (23%), Positives = 167/380 (43%), Gaps = 37/380 (9%)
Query: 26 GDKIEVSLTETIFYPRGGGQPGDKGKIRGDGFEIIVEDTVERDGEIW-HVGKLNGRTPEV 84
GD V L T FY GGQ GD+G+++ + V DT + G + H+G++ ++
Sbjct: 486 GDMGVVILDRTPFYGESGGQAGDRGELQSNDALFAVTDTQKPMGHLHVHLGRVESGRLQI 545
Query: 85 GEEVELELDWEWRYGNMQMHTGQHILSAVLKKRYDLDTSGFNIFGDYAKIE---VNGE-- 139
G+ V +D R H+ H+L A L+ NI G + + + VN E
Sbjct: 546 GDMVVASVDEVARRATAAHHSATHLLHAALR----------NILGSHVQQKGSLVNPERL 595
Query: 140 ---------LNWEMIEEAELEANKVIIDDLPVRVEEYEVLPKGVVEKLRKYIPNIKGKIR 190
+ + E E N I +++ V + + + ++R
Sbjct: 596 RFDFSHPEPVTAAQLREIERVVNAAIRNNVGAETRILPVAEAQALGAMALFGEKYGDEVR 655
Query: 191 IVRIGENFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFTCGFRAIKKLNEILKD 250
+VR+G+ F + CGGTHV++ ++GV K+L + RIE G A++ + +
Sbjct: 656 VVRMGD-FSMELCGGTHVEALGDIGVFKILSESGVAAGIRRIEAVTGAVALEAIQRDEER 714
Query: 251 YWSALDAMPNKNPPLSERVREVLESVESLEEKVDSMRKEVWKWKEESLLGRSIEIGHYNV 310
+A + L +R+ + LE + LE++++ ++++ L + ++G V
Sbjct: 715 LQAAAGLLKVAPAELDQRLAQTLERLRQLEKELEKVKRDEAVRAGAGLAAEAEDVG--GV 772
Query: 311 VTFVEKWDIKDAQAF--AVDFVKNN-PGTIVVLAS---EDYVILA---RNEEVEVSMKSL 361
+ + + D +A A+D +++ P ++VLA E ++A + V L
Sbjct: 773 PVLIRRLEGMDGKALRDALDRLRSQLPDGVIVLAGVEREKVALIAGVGKGLTGRVHAGEL 832
Query: 362 LEDLIKEFGGKGGGTDNLAR 381
+ + + GGKGGG LA+
Sbjct: 833 VNTVAQPLGGKGGGRPELAQ 852
>pir||G72685 probable alanyl-tRNA synthetase APE0903 - Aeropyrum pernix (strain
K1) >gi|5104572|dbj|BAA79887.1| (AP000060) 274aa long
hypothetical alanyl-tRNA synthetase [Aeropyrum pernix]
Length = 274
Score = 94.4 bits (231), Expect = 2e-18
Identities = 82/240 (34%), Positives = 125/240 (51%), Gaps = 17/240 (7%)
Query: 5 LYYVDPYLKTAKAKISDLTIKGDKIEVSLTETIFYPRG-GGQPGDKGKI-RGDGFEIIVE 62
LY D YL+ +A++ + + G + V L T F+P GG D G I GD +V
Sbjct: 31 LYQQDSYLREFEARVEEAS--GGR--VVLDRTAFHPGPHGGLDTDTGYIFYGDKRYRVVR 86
Query: 63 DTVERDGEIWHVGKLNGRTPEVGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRYDLDT 122
VE D + H + T E G V+ +DWE RY M++HT HIL+AVL +++D+
Sbjct: 87 AAVEGD-VVAHYLDSDTATLEPGAVVKGVIDWERRYRMMRLHTFSHILAAVLYEKHDVLV 145
Query: 123 SGFNIFGDYAK--IEVNGELNWEMIEEAELEANKVIIDDLPVRV-----EEYEVLPKGVV 175
+G +I DY K + G E+IEEA EAN++ + V+V EE +P G+V
Sbjct: 146 TGGHITPDYGKDDFSIEGGGWREVIEEAFREANEIASRCIEVKVYWLPREEALKIP-GIV 204
Query: 176 EKLRKYIPNIKGKIRIVRIGENFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFT 235
+ K P ++ +RIV I D+ GG HV++T E+G + + + K K R+ +T
Sbjct: 205 KLANKLPPEVE-TLRIVEI-PGVDVQADGGPHVRNTCEIGRVVITKLESKGKRRKRVYYT 262
>pir||C75511 alanyl-tRNA synthetase-related protein - Deinococcus radiodurans
(strain R1) >gi|6458192|gb|AAF10082.1|AE001909_4
(AE001909) alanyl-tRNA synthetase-related protein
[Deinococcus radiodurans]
Length = 409
Score = 93.6 bits (229), Expect = 4e-18
Identities = 95/398 (23%), Positives = 165/398 (40%), Gaps = 30/398 (7%)
Query: 1 MARKLYYVDPYLKTAKAKISDLTIKGDKIEVSLTETIFYPRGGGQPGDKGKIRGDGFEII 60
M R LY+ DPY A S + ++G EV+L T FYP GGQ D G +R G E
Sbjct: 20 MTRPLYH-DPYQPLTFAA-SVVDVQGQ--EVALAATAFYPESGGQSSDVGLLRWPGSEAR 75
Query: 61 VEDT--VERDGEIWHVGKLNGRTPEVGEEVELELDWEWRYGNMQMHTGQHILSAVLKK-R 117
V + G +WH +++G P VG EV E+D R+ + Q H+ +H+L+ ++
Sbjct: 76 VTHARKDKATGTVWH--RVDGELPPVGAEVTGEVDPGPRWRHTQRHSAEHLLAQAFRRVN 133
Query: 118 YDLDTSGFNIFGDYAKIEVNGELNWEMIEEAELEANKVIIDDLPVRVE---EYEVLPKG- 173
+ + N+ G I+ G+ EA++ A + ++ + R E E ++P+
Sbjct: 134 PAFEVASVNMTGPECTIDFLGDPG-----EADIRAAEALLRETLGRDELTLETPIVPEAE 188
Query: 174 VVEKLRKYIPNIKGKIRIVRI----GENFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDT 229
+V + + G++R+V G+ FD++ CGGTHV + +LR +
Sbjct: 189 LVNYPLRRESKVGGQVRLVMFRGSDGDFFDVSACGGTHVPGAAMCAPVVILRTERVRGGQ 248
Query: 230 WRIEFTCGFRAIKKLNEILKDYWSALDAMPNKNPPLSERVREVLESVESLEEKVDSMRKE 289
R+ F G A + L+ + + + L ERV + + + D++R
Sbjct: 249 VRVVFMAGEEASEYLSGVYQSARTLAQEFSAPVDKLPERVAALRADLSAARADADALRAR 308
Query: 290 VWKWKEESLLGRSIEIGHYNVVTFVEKWDIKDAQAFAVDFVKNNPGTIVVLASEDYVILA 349
L + + + + +A A G ++
Sbjct: 309 --------LAAQLVAAASAEGTPPLRLLTLDNAALLAPVLTAVPAGEVLAAVGPGGRCGV 360
Query: 350 RNEEVEVSMKSLLEDLIKEFGGKGGGTDNLARGKIEAE 387
+ +V +L + GGKGGG +LA+G E
Sbjct: 361 ASAHPDVKAGDVLRAALAVTGGKGGGKPDLAQGSTADE 398
>emb|CAC11978.1| (AL445065) alanyl-tRNA synthetase related protein [Thermoplasma
acidophilum]
Length = 871
Score = 92.4 bits (226), Expect = 8e-18
Identities = 87/313 (27%), Positives = 139/313 (43%), Gaps = 37/313 (11%)
Query: 3 RKLYYVDPYLKTAKAKISDLTIKGDKIEVSLTETIFYPRGGGQPGDKGKIRGDGFEIIVE 62
R LYY DP+++ + L KG+ E+ L +T FYP GGGQP D G G I V
Sbjct: 496 RTLYYDDPFMREFTGLV--LFSKGN--EIILDKTAFYPEGGGQPWDLGYFEYKGKRINVV 551
Query: 63 DTVERDGEIWHVGKLNGRTPEVGEEVELELDWEWRYGNMQMHTGQHILSAVLKK------ 116
+ I H L+G P+ G V +DWE R M HT H+L VL++
Sbjct: 552 AVRKYGKTIVHT--LDGEIPQ-GVRVHGVIDWERRSRLMVHHTSTHLLLGVLREVLGEHV 608
Query: 117 -----RYDLDTSGFNIFGDYAKIEVNGELNWEMIEEAELEANKVIIDDLPVRVEE---YE 168
+ D++ S +I Y KI+ E I + E +I + V V Y
Sbjct: 609 WQNGVQKDVEESRLDIT-HYRKIDE------ETIRKIEERVFDLIREGREVSVRNLDWYS 661
Query: 169 VLPKGVVEKLRKYIPNIKGKIRIVRIGENFDLTPCGGTHVKSTREVGVIKVLRFYKKSKD 228
+ K +P + KIR+V I + D CGGTH+K+ +GV+K+ + ++
Sbjct: 662 AIDKYGFRLFEGGVP-LTPKIRVVEI-QGVDAEGCGGTHLKNISSIGVLKIRKVEAIQEN 719
Query: 229 TWRIEFTCGFRAIKKLNEILKDYWSALDAMPNKNPPLSERVREVLESVESLEEKVDSMRK 288
+RI F+ G A+ E + +A + L + + E+ +SV L + +R+
Sbjct: 720 IYRITFSAGVPALHLFQE-------SYEASYGISTLLKKPIEEIAQSVSELSKGYADLRR 772
Query: 289 EVWKWKEESLLGR 301
+ + + + R
Sbjct: 773 SLAEARRRDIENR 785
>sp|O27718|SYA_METTH ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|7437627|pir||A69092 alanine--tRNA ligase (EC
6.1.1.7) - Methanobacterium thermoautotrophicum (strain
Delta H) >gi|2622813|gb|AAB86155.1| (AE000926)
alanyl-tRNA synthetase [Methanobacterium
thermoautotrophicum]
Length = 898
Score = 92.1 bits (225), Expect = 1e-17
Identities = 102/426 (23%), Positives = 184/426 (42%), Gaps = 60/426 (14%)
Query: 5 LYYVDPYLKTAKAKISDLTIKGDKIEVSLTETIFYPRGGGQPGDKGKIRGDGFEIIVEDT 64
L+Y +P +A++ + G + L T+FYP GGGQP D G I +G + ++
Sbjct: 495 LFYDEPDDLEFQAEVIGIHENG----LILDRTLFYPEGGGQPSDTGYITAEGCRLRIKHA 550
Query: 65 VERDGEIWHVGKLNGRTP-----EVGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRYD 119
+ + H RT E G + +D + R + HT H++ + +K
Sbjct: 551 EKIGAVVVH------RTDDEICIEPGTTIRGFIDSDRRLQLTRNHTATHLIVSAARK--- 601
Query: 120 LDTSGFNIFGDYAKIEVNGE---------LNWEMIEEAELEANKVIIDDLPVRVEEYEVL 170
G +I+ A+ V + E ++E E AN+ ++ ++P++V +
Sbjct: 602 --VLGDHIWQAGAQKGVKSSRLDLSHYRRITLEELQEIERLANEYVMMNVPLKVRWMD-- 657
Query: 171 PKGVVEKLRKYIPNIKG-----KIRIVRIGENFDLTPCGGTHVKSTREVGVIKVLRFYKK 225
+ + E+ +I G +IR+V I D+ C GTHV T ++G+I++ R +
Sbjct: 658 -RDLAERKYGFILYQGGVVPGSRIRVVEI-PGVDVQACAGTHVHRTGDIGLIRINRTERI 715
Query: 226 SKDTWRIEFTCGFRAI---KKLNEILKDYWSALDAMPNKNPPLSERVREVLESVESLEEK 282
RIEF+ G AI +K +IL++ P++ P ER ++L +
Sbjct: 716 QDGVERIEFSAGSAAIEIMQKTGDILRESSDIFKVTPSQLPGTCER---FFTEWKALRNE 772
Query: 283 VDSMRKEVWKWKEESLLGRSIEIGHYNVVTFVEKWDIKDAQAFAVDF--------VKNNP 334
V ++++V K + R+ I V+ D+ + + A++ + N
Sbjct: 773 VSRLKEKVASLKILEMKDRAERINDLTVIIDTVDADMDEMKNMALELSATVDAVVLANPE 832
Query: 335 GTIVVLASEDYVILARNEEVEVSMKSLLEDLIKEFGGKGGGTDNLARGKIEAEPEDVIDF 394
G IV ASED V + + + ++ GG GGG +LA+G A D +D
Sbjct: 833 GKIVGAASEDAV------KAGLRINEVISQAAAVLGGGGGGRPHLAQGAGPA--TDKVDE 884
Query: 395 VVDRLR 400
++ R
Sbjct: 885 ALEEAR 890
>pir||H81739 alanyl-tRNA synthetase TC0125 [imported] - Chlamydia muridarum
(strain Nigg) >gi|7190160|gb|AAF39003.1| (AE002279)
alanyl-tRNA synthetase [Chlamydia muridarum]
Length = 875
Score = 90.9 bits (222), Expect = 2e-17
Identities = 89/387 (22%), Positives = 176/387 (44%), Gaps = 17/387 (4%)
Query: 18 KISDLTIKGDKIEVSLTETIFYPRGGGQPGDKGKIRGD-GFEIIVEDTVERDGEIWHVGK 76
+I+ +G++ + L T FY GGQ GD G+I + G ++ T + G I H GK
Sbjct: 474 EIASTLEEGEEGAIILRTTPFYAEKGGQVGDSGEIFCESGTFLVSHTTTPKAGLIAHHGK 533
Query: 77 LNGRTPEVGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRYDLDTSGFNIFGDYAKIEV 136
L+ + + V +++ R HTG H+L L+ + D KI +
Sbjct: 534 LSQGSLQTTMAVTAQVNQNLRKKIANNHTGCHLLHKALEVSLGEHIRQAGSYVDSQKIRL 593
Query: 137 ----NGELNWEMIEEAELEANKVIIDDLPVRVEEYEVLPKGVVEKLRKYIPNIKGKI-RI 191
N L+ E + E N+ I +++PV + E +++++ + G I R+
Sbjct: 594 DFSHNKALSPEELLTIETLVNEKIRENVPVTIREALYSDVMNSSEIKQFFGDKYGDIVRV 653
Query: 192 VRIGENFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFTCGFRAIKKLNEILKDY 251
V G + +L CGGTH ++T ++G ++ + + S RIE T G A D
Sbjct: 654 VSAGFSHEL--CGGTHARATGDIGYFRITKEHAVSTGIRRIEATTGEDAENIARGQDTDL 711
Query: 252 WSALDAMPNKNPPLSERVREVLESVESLEEKVDSMRKEVWKWKEESLLGRSIEIGHYNVV 311
+ + L ++R V+E + L +++ ++ ++ + + +SLL ++ + +
Sbjct: 712 NEIATIIQSPKDQLLVKLRNVMEEKKDLAKQLANLENQLVQQQVKSLLTSCDKVNETSYL 771
Query: 312 TF-VEKWDIKDAQAFAVDFVKNNPGTIVVL----ASEDYVILARNEE----VEVSMKSLL 362
+ + + + + Q +A K P + L ++ Y++L R + + ++LL
Sbjct: 772 VYHLTEEEGQRIQHYANTLHKEVPAKFISLWVTEKNDRYIVLVRVSDDLVKQGIDAQALL 831
Query: 363 EDLIKEFGGKGGGTDNLARGKIEAEPE 389
E+L+ +GG+ GG A+G + P+
Sbjct: 832 EELLAPYGGRCGGKAVSAQGSSKELPQ 858
>pir||F81063 alanyl-tRNA synthetase NMB1595 [imported] - Neisseria meningitidis
(group B strain MD58) >gi|7226845|gb|AAF41948.1|
(AE002510) alanyl-tRNA synthetase [Neisseria
meningitidis MC58]
Length = 874
Score = 90.9 bits (222), Expect = 2e-17
Identities = 91/396 (22%), Positives = 174/396 (42%), Gaps = 21/396 (5%)
Query: 25 KGDKIEVSLTETIFYPRGGGQPGDKGKIRGDGFEIIVEDTVERDGEIW-HVGKLNGRTPE 83
+GD V + T FY GGQ GD G I V DT + ++ G +
Sbjct: 482 EGDSGAVVIDFTPFYAESGGQVGDVGYIFSGENRFEVRDTQKIKAAVFGQFGVQTSGRLK 541
Query: 84 VGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRYD--LDTSGFNIFGDYAKIEVNGE-- 139
VG+ V ++D E R NM+ H+ H++ L+ ++ G + + + +++
Sbjct: 542 VGDSVTAKVDDEIRNANMRNHSATHLMHKALRDVLGRHVEQKGSLVTAESTRFDISHPQA 601
Query: 140 LNWEMIEEAELEANKVIIDDLPVRVEEYEVLPKGVVEKLRKYIPNIKGKIRIVRIGENFD 199
+ E I E E N+ I+ ++ V + + + ++R++++G F
Sbjct: 602 VTAEEIAEVERRVNEAILANVAVNAAIMSMEDAQKTGAMMLFGEKYGEEVRVLQMG-GFS 660
Query: 200 LTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFTCGFRAIKKLNE---ILKDYWSALD 256
CGGTHV T ++G+ K++ + RIE G A+K E ++KD +
Sbjct: 661 TELCGGTHVSRTGDIGLFKIISEGGIAAGVRRIEAITGLNALKWAQEQERLVKDIIAETK 720
Query: 257 AMPNKNPPLSERVREVLESVESLEEKVDSMRKEVWKWKEESLLGRSIEIGHYNVVTFVEK 316
A K+ + +++ ++LE+++ + E+ LL + ++G +V +
Sbjct: 721 AQTEKD--VLAKIQAGAAHAKALEKELARAKAELAVHAGAKLLDDAKDLGAAKLVAAQIE 778
Query: 317 WDIKDAQAFAVDFVKNNPGTIVVLA--SEDYVILARNEEVEVSMKSLLEDLIK----EFG 370
D + D + +++LA ++ V L ++ K DL+K + G
Sbjct: 779 ADAAALREIVTDLTGKSDNAVILLAAVNDGKVSLCAGVSKPLTGKVKAGDLVKFAAEQVG 838
Query: 371 GKGGGTDNLAR-GKIEAEPEDVIDFVVDRLREIIGA 405
GKGGG +LA+ G +A D + V+D +++ +GA
Sbjct: 839 GKGGGRPDLAQAGGTDA---DKLPAVLDSVKDWVGA 871
>sp|O84754|SYA_CHLTR ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|6578113|gb|AAC68344.2| (AE001346) Alanyl tRNA
Synthetase [Chlamydia trachomatis]
Length = 875
Score = 89.3 bits (218), Expect = 7e-17
Identities = 95/394 (24%), Positives = 178/394 (45%), Gaps = 19/394 (4%)
Query: 25 KGDKIEVSLTETIFYPRGGGQPGDKGKIRGDGFEIIVEDTVE-RDGEIWHVGKLNGRTPE 83
+GD+ + L T FY GGQ GD G+I + +V T+ + G I H+GKL+ +
Sbjct: 481 EGDEGAIILRTTPFYAGKGGQIGDSGEIFCESGTFLVSHTIAPKAGLIVHLGKLSQGSLT 540
Query: 84 VGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRYDLDTSGFNIFGDYAKIEV----NGE 139
V +++ R HTG H+L L+ + D KI + N
Sbjct: 541 TTMAVTAQVNQNLRKKTANNHTGCHLLHKALEMTLGEHIRQAGSYVDSQKIRLDFTHNKA 600
Query: 140 LNWEMIEEAELEANKVIIDDLPVRVEEYEVLPKGVVEKLRKYIPNIKGKI-RIVRIGENF 198
L+ E + E N+ I ++ PV + E +++++ + G I R+V G +
Sbjct: 601 LSPEDLLAIETLVNEKIRENDPVTIREVLYSDVMSSSEIKQFFGDKYGDIVRVVSAGFSH 660
Query: 199 DLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFTCGFRAIKKLNEILKDYWSALDAM 258
+L CGGTH ++T ++G ++ + + + RIE T G A E D +
Sbjct: 661 EL--CGGTHAQATGDIGYFRITKEHAVATGIRRIEATTGEDAENIAREQDVDLNEIATVI 718
Query: 259 PNKNPPLSERVREVLESVESLEEKVDSMRKEVWKWKEESLLGRSIEIGHYN-VVTFVEKW 317
+ + ++R V+E + L ++V + ++ + + ++LL +I + +V ++ +
Sbjct: 719 QSPKDQILVKIRSVMEEKKDLAKQVADLENQLVQQQVKTLLTSCEKICDTSYLVYYLTEE 778
Query: 318 DIKDAQAFAVDFVKNNPGTIVVL----ASEDYVILARNEE----VEVSMKSLLEDLIKEF 369
+ + Q +A K P + L + Y++L+R + V +LL +L+ +
Sbjct: 779 EGQRIQHYANAIHKEIPTNFISLWITEKNGRYIVLSRVSDDLTKRGVQAHTLLAELLAPY 838
Query: 370 GGKGGGTDNLARGKIEAEPEDVIDFVVDRLREII 403
GG+ GG A+G P+ I+F+ LR+ I
Sbjct: 839 GGRCGGKAISAQGSSAELPQ--IEFLNKTLRQWI 870
>pir||E71476 alanine--tRNA ligase (EC 6.1.1.7) - Chlamydia trachomatis
(serotype D, strain UW3/Cx)
Length = 924
Score = 89.3 bits (218), Expect = 7e-17
Identities = 95/394 (24%), Positives = 178/394 (45%), Gaps = 19/394 (4%)
Query: 25 KGDKIEVSLTETIFYPRGGGQPGDKGKIRGDGFEIIVEDTVE-RDGEIWHVGKLNGRTPE 83
+GD+ + L T FY GGQ GD G+I + +V T+ + G I H+GKL+ +
Sbjct: 530 EGDEGAIILRTTPFYAGKGGQIGDSGEIFCESGTFLVSHTIAPKAGLIVHLGKLSQGSLT 589
Query: 84 VGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRYDLDTSGFNIFGDYAKIEV----NGE 139
V +++ R HTG H+L L+ + D KI + N
Sbjct: 590 TTMAVTAQVNQNLRKKTANNHTGCHLLHKALEMTLGEHIRQAGSYVDSQKIRLDFTHNKA 649
Query: 140 LNWEMIEEAELEANKVIIDDLPVRVEEYEVLPKGVVEKLRKYIPNIKGKI-RIVRIGENF 198
L+ E + E N+ I ++ PV + E +++++ + G I R+V G +
Sbjct: 650 LSPEDLLAIETLVNEKIRENDPVTIREVLYSDVMSSSEIKQFFGDKYGDIVRVVSAGFSH 709
Query: 199 DLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFTCGFRAIKKLNEILKDYWSALDAM 258
+L CGGTH ++T ++G ++ + + + RIE T G A E D +
Sbjct: 710 EL--CGGTHAQATGDIGYFRITKEHAVATGIRRIEATTGEDAENIAREQDVDLNEIATVI 767
Query: 259 PNKNPPLSERVREVLESVESLEEKVDSMRKEVWKWKEESLLGRSIEIGHYN-VVTFVEKW 317
+ + ++R V+E + L ++V + ++ + + ++LL +I + +V ++ +
Sbjct: 768 QSPKDQILVKIRSVMEEKKDLAKQVADLENQLVQQQVKTLLTSCEKICDTSYLVYYLTEE 827
Query: 318 DIKDAQAFAVDFVKNNPGTIVVL----ASEDYVILARNEE----VEVSMKSLLEDLIKEF 369
+ + Q +A K P + L + Y++L+R + V +LL +L+ +
Sbjct: 828 EGQRIQHYANAIHKEIPTNFISLWITEKNGRYIVLSRVSDDLTKRGVQAHTLLAELLAPY 887
Query: 370 GGKGGGTDNLARGKIEAEPEDVIDFVVDRLREII 403
GG+ GG A+G P+ I+F+ LR+ I
Sbjct: 888 GGRCGGKAISAQGSSAELPQ--IEFLNKTLRQWI 919
>dbj|BAB10601.1| (AB005243) alanyl-tRNA synthetase [Arabidopsis thaliana]
Length = 954
Score = 89.3 bits (218), Expect = 7e-17
Identities = 99/388 (25%), Positives = 167/388 (42%), Gaps = 39/388 (10%)
Query: 25 KGDKIEVSLTETIFYPRGGGQPGDKG--KIRGDGFE---IIVEDTVERDGEIW-HVGKLN 78
+G ++EV L T FY GGQ D G + DG + ++ V++ +I+ H G +
Sbjct: 546 EGSEVEVLLDRTPFYAESGGQIADHGFLYVSSDGNQEKAVVEVSDVQKSLKIFVHKGTVK 605
Query: 79 GRTPEVGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRYDLDTS--GFNIFGDYAKIEV 136
EVG+EVE +D + R HT H+L + LKK +TS G + D + +
Sbjct: 606 SGALEVGKEVEAAVDADLRQRAKVHHTATHLLQSALKKVVGQETSQAGSLVAFDRLRFDF 665
Query: 137 N--GELNWEMIEEAELEANKVIIDDLPVRVEEYEVLPKGVVEKL-------RKYIPNIKG 187
N L+ +EE E N+ I D + E +VLP ++ KY N
Sbjct: 666 NFNRSLHDNELEEIECLINRWIGDATRL---ETKVLPLADAKRAGAIAMFGEKYDEN--- 719
Query: 188 KIRIVRI-GENFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFTCGFRAIKKLNE 246
++R+V + G + +L CGGTHV +T E+ K++ + RIE G I+ +N
Sbjct: 720 EVRVVEVPGVSMEL--CGGTHVGNTAEIRAFKIISEQGIASGIRRIEAVAGEAFIEYINS 777
Query: 247 ILKDYWSALDAMPNKNPPLSERVREVLESVESLEEKVDSMRKEVWKWKEESLLGRSIEIG 306
+ K ++ RV +LE + + ++ +R + +K + ++ +G
Sbjct: 778 RDSQMTRLCSTLKVKAEDVTNRVENLLEELRAARKEASDLRSKAAVYKASVISNKAFTVG 837
Query: 307 HYNVV-TFVEKWDIKDAQAFA-----VDFVKNNPGTIVVLAS--EDYVILARN-----EE 353
+ VE D DA + + +P +V+ +S +D V L
Sbjct: 838 TSQTIRVLVESMDDTDADSLKSAAEHLISTLEDPVAVVLGSSPEKDKVSLVAAFSPGVVS 897
Query: 354 VEVSMKSLLEDLIKEFGGKGGGTDNLAR 381
+ V + + K GG GGG N A+
Sbjct: 898 LGVQAGKFIGPIAKLCGGGGGGKPNFAQ 925
>sp|O07438|SYA_MYCTU ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|7437633|pir||C70520 probable alaS protein -
Mycobacterium tuberculosis (strain H37RV)
>gi|3261815|emb|CAB09762.1| (Z97051) alaS [Mycobacterium
tuberculosis]
Length = 904
Score = 88.9 bits (217), Expect = 9e-17
Identities = 94/407 (23%), Positives = 178/407 (43%), Gaps = 37/407 (9%)
Query: 25 KGDKIEVSLTETIFYPRGGGQPGDKGKIRGDGFE----IIVEDTVERDGEIWHVGKLNGR 80
+G ++E+ L T Y GGQ D+G I G G V D + +W V ++N
Sbjct: 500 EGQRVELVLDRTPLYAESGGQIADEGTISGTGSSEAARAAVTDVQKIAKTLW-VHRVNVE 558
Query: 81 TPEV--GEEVELELDWEWRYGNMQMHTGQHILSAVLKKRYD---LDTSGFNIFGDYAKIE 135
+ E G+ V +D WR G Q H+G H++ A L++ + N G Y + +
Sbjct: 559 SGEFVEGDTVIAAVDPGWRRGATQGHSGTHMVHAALRQVLGPNAVQAGSLNRPG-YLRFD 617
Query: 136 VN--GELNWEMIEEAELEANKVIIDDLPVRVEEYEVLPKGVVEKLRKYIPNIKGKIRIVR 193
N G L + + E N+ + D VR ++ + + + + ++R+V
Sbjct: 618 FNWQGPLTDDQRTQVEEVTNEAVQADFEVRTFTEQLDKAKAMGAIALFGESYPDEVRVVE 677
Query: 194 IGENFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFTCG---FRAIKKLNEILKD 250
+G F L CGGTHV +T ++G + +L R+E G FR + K ++
Sbjct: 678 MGGPFSLELCGGTHVSNTAQIGPVTILGESSIGSGVRRVEAYVGLDSFRHLAKERALMAG 737
Query: 251 YWSALDAMPNKNPPLSERVREVLESVESLEEKVDSMRKEVWKWKEESLLGRSIEIGHYNV 310
S+L +P++ P RV ++E + + E++++ +R + + + IG+ +
Sbjct: 738 LASSL-KVPSEEVP--ARVANLVERLRAAEKELERVRMASARAAATNAAAGAQRIGNVRL 794
Query: 311 VT-----FVEKWDIKDAQAFAVDFVKNNPGTIVVLASED-----YVILARNEEVEVSMKS 360
V + D++ + + P + ++A + Y + A ++ +++
Sbjct: 795 VAQRMSGGMTAADLRSLIGDIRGKLGSEPAVVALIAEGESQTVPYAVAANPAAQDLGIRA 854
Query: 361 LLEDLIKEFG----GKGGGTDNLARGKIEAEPEDVIDFVVDRLREII 403
DL+K+ G+GGG +LA+G + ID +D +R I
Sbjct: 855 --NDLVKQLAVAVEGRGGGKADLAQG--SGKNPTGIDAALDAVRSEI 897
>gb|AAG23689.1|AF297520_1 (AF297520) alanyl-tRNA synthase [Haemophilus ducreyi]
Length = 783
Score = 88.5 bits (216), Expect = 1e-16
Identities = 85/376 (22%), Positives = 173/376 (45%), Gaps = 22/376 (5%)
Query: 21 DLTIKGDKIEVSLTETIFYPRGGGQPGDKGKIRGDGFEIIVEDTVERDGEIWHVGKLNGR 80
D G+ V L +T FY GGQ GD G I + V DT + H+G++
Sbjct: 389 DKVQSGESAVVVLDKTPFYAEMGGQVGDSGLITTAFCQFAVADTQKYGQVFGHIGQVVSG 448
Query: 81 TPEVGEEVELELDWEWRYGNMQMHTGQHILSAVLKK--RYDLDTSGFNIFGDYAKIEVNG 138
+ +G+ + ++D R H+ H+L + L++ + G + + + + +
Sbjct: 449 SLAIGDIISAQVDIARRQAITANHSATHLLHSALRQVLGEHVVQKGSLVSENVLRFDFSQ 508
Query: 139 E--LNWEMIEEAELEANKVIIDDLPVRVEEYEV---LPKGVVEKLRKYIPNIKGKIRIVR 193
++ +EE E N+ I +L V +E ++ KG V + ++ +R+V
Sbjct: 509 SQAVSKAQLEEIERIVNRQIRQNLAVTIETMDIETAKEKGTVALFGEKYGDV---VRVVG 565
Query: 194 IGENFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFTCGFRAIKKLNEILKDYWS 253
+ +F + CGGTHVK T E+G+ K++ + R+E AI L+ K
Sbjct: 566 M-TDFSIELCGGTHVKHTGEIGLFKLISESAVAAGIRRVEALTAENAINWLHNQQKIIHQ 624
Query: 254 ALDAMPNKNPPLSERVREVLESVESLEEKVDSMRKEVWKWKEESLLGRSIEIGHYNVVTF 313
+ + + + L +++ ++ + ++ E+++ + ++ L + ++I NVV
Sbjct: 625 SAELLKTDSLSLVDKIYQLQDKIKRNEKELQHFKDKLAAQAGAELAKQVVQINGINVV-- 682
Query: 314 VEKWDIKDAQAF--AVDFVKNNPGTIVVL---ASEDYVILARNEEVEVSMKSLLEDLI-- 366
++K + ++++ VD +KN +++V+ S D V L ++S K +L+
Sbjct: 683 IQKLEGIESKSLRTMVDDLKNQLSSVIVVFGSVSADKVNLIVGVTKDLSNKVNAGELVGL 742
Query: 367 --KEFGGKGGGTDNLA 380
++ GGKGGG ++A
Sbjct: 743 IAQQVGGKGGGRPDMA 758
>pir||C81804 alanine--tRNA ligase (EC 6.1.1.7) NMA1788 [imported] - Neisseria
meningitidis (group A strain Z2491)
>gi|7380429|emb|CAB85015.1| (AL162757) alanyl-tRNA
synthetase [Neisseria meningitidis Z2491]
Length = 874
Score = 86.6 bits (211), Expect = 5e-16
Identities = 83/371 (22%), Positives = 160/371 (42%), Gaps = 17/371 (4%)
Query: 25 KGDKIEVSLTETIFYPRGGGQPGDKGKIRGDGFEIIVEDTVERDGEIW-HVGKLNGRTPE 83
+GD V + T FY GGQ GD G I V DT + ++ G +
Sbjct: 482 EGDSGAVVIDFTPFYAESGGQVGDVGYIFSSENRFEVRDTQKIKAAVFGQFGVQTSGRLK 541
Query: 84 VGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRYD--LDTSGFNIFGDYAKIEVNGE-- 139
VG+ V ++D E R NM+ H+ H++ L+ ++ G + + + +++
Sbjct: 542 VGDSVTAKVDDEIRNANMRNHSATHLMHKALRDVLGGHVEQKGSLVTAESTRFDISHPQA 601
Query: 140 LNWEMIEEAELEANKVIIDDLPVRVEEYEVLPKGVVEKLRKYIPNIKGKIRIVRIGENFD 199
+ E I E E N+ ++ ++ V + + + ++R++++G F
Sbjct: 602 VTAEEIAEVERRVNEAVLANVAVNAAIMSMEDAQKTGAMMLFGEKYGEEVRVLQMG-GFS 660
Query: 200 LTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFTCGFRAIKKLNE---ILKDYWSALD 256
CGGTHV T ++G+ K++ + RIE G A+K E ++KD +
Sbjct: 661 TELCGGTHVSRTGDIGLFKIISEGGIAAGVRRIEAITGLNALKWAQEQERLVKDIIAETK 720
Query: 257 AMPNKNPPLSERVREVLESVESLEEKVDSMRKEVWKWKEESLLGRSIEIGHYNVVTFVEK 316
A K+ + +++ ++LE+++ + E+ LL + ++G +V +
Sbjct: 721 AQTEKD--VLAKIQAGAAHAKALEKELARAKAELAVHAGAKLLDDAKDLGAAKLVAAQIE 778
Query: 317 WDIKDAQAFAVDFVKNNPGTIVVLA--SEDYVILARNEEVEVSMKSLLEDLIK----EFG 370
D + D + +++LA ++ V L ++ K DL+K + G
Sbjct: 779 ADAAALREIVTDLTGKSDNAVILLAAVNDGKVSLCAGVSKPLTGKVKAGDLVKFAAEQVG 838
Query: 371 GKGGGTDNLAR 381
GKGGG +LA+
Sbjct: 839 GKGGGRPDLAQ 849
>sp|P74941|SYA_THETH ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|1565288|emb|CAA69650.1| (Y08363) alanyl-tRNA
synthatase [Thermus thermophilus]
Length = 882
Score = 84.7 bits (206), Expect = 2e-15
Identities = 98/374 (26%), Positives = 159/374 (42%), Gaps = 21/374 (5%)
Query: 26 GDKIEVSLTETIFYPRGGGQPGDKGKIRGDGFEIIVEDTVERD-GEIWHVGKLNGRTPEV 84
G +++V L +T FY GGGQ GD G + G VE T + + G H ++ V
Sbjct: 496 GTEVQVVLDKTPFYAEGGGQIGDFGLLEWPGGRARVETTRKTERGIFLHKARVEEGVLRV 555
Query: 85 GEEVELELDWEWRYGNMQMHTGQHILSAVLKKRY--DLDTSGFNIFGDYAKIEVN--GEL 140
GE V +D R + HT H+L A L+ + +G + D + + L
Sbjct: 556 GERVRAVVD-PRRRDTERNHTATHLLHAALRAVLGPHVRQAGSLVAPDRLRFDFTHPEPL 614
Query: 141 NWEMIEEAELEANKVIIDDLPVRVEEYEVLPKGVVEKLRKYIPNIKGK-IRIVRIG---- 195
E +E EL N+ I+ D PV Y L + E G+ +R+VR+
Sbjct: 615 KPEELERVELLVNRWIMADFPV-TWRYMPLEEARKEGAMALFGEKYGEVVRVVRVEGSPL 673
Query: 196 ---ENFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFTCGFRAIKKLNEILKDYW 252
E+ +L CGG HV+ T E+G + S RIE G AI+ L
Sbjct: 674 EGLESKEL--CGGCHVRRTGEIGAFLIRSEEAVSAGVRRIEAVTGEEAIRFARGSLNRLK 731
Query: 253 SALDAMPNKNPPLSERVREVLESVESLEEKVDSMRKEVWKWKEESLLGRSIEI--GHYNV 310
+ + + L ER+ ++L ++ E +V+S++ + + G S+E G
Sbjct: 732 ALAERLEVGEAALEERLEKLLAELKEKEREVESLKARLVQAALGGGGGASLEEKGGLRWT 791
Query: 311 VTFVEKWDIKDAQAFAVDFVKNNPGTIVVLASEDYV--ILARNEEVEVSMKSLLEDLIKE 368
V + D K + A D V +VL+ V + + + + + +L L ++
Sbjct: 792 VAELPGLDAKALRQAADDLVARGADVALVLSGGQAVLKLSPKAQGMGLEAGALFRALAEK 851
Query: 369 FGGKGGGTDNLARG 382
GG+GGG LA+G
Sbjct: 852 AGGRGGGKGALAQG 865
>pir||C81396 alanine--tRNA ligase (EC 6.1.1.7) Cj0506 [imported] - Campylobacter
jejuni (strain NCTC 11168) >gi|6967975|emb|CAB75143.1|
(AL139075) alanyl-tRNA synthetase [Campylobacter jejuni]
Length = 842
Score = 83.1 bits (202), Expect = 5e-15
Identities = 87/358 (24%), Positives = 154/358 (42%), Gaps = 29/358 (8%)
Query: 31 VSLTETIFYPRGGGQPGDKGKIRGDGFEIIVEDTVERDGEIWHVGKLNGRTPEVGEEVEL 90
V L T FY GGQ D G I + V DT + K G +V + V
Sbjct: 481 VMLENTPFYATSGGQSADSGFIA----KREVLDTQKFFNLNLSFIKA-GEELKVNDIVHA 535
Query: 91 ELDWEWRYGNMQMHTGQHILSAVLKKRYDLDTSGFNIFGDYAKIEVN----GELNWEMIE 146
+D E R + H+ H+L L++ S + K+ + LN E +E
Sbjct: 536 RIDTEKREQIARHHSATHLLHHALREILGSHVSQAGSLVESNKLRFDFTHHKALNKEELE 595
Query: 147 EAELEANKVIIDDLPVRVEEYEVLPKGVVEKLRKYIPNIKGKIRIVRIGENFDLTPCGGT 206
E NK+II+ +E + + + +G +R++ +GE+ +L CGGT
Sbjct: 596 SIEKRVNKMIINSSEAILENMPLEEAKKSGAIALFNEKYQGNVRVLTLGESKEL--CGGT 653
Query: 207 HVKSTREVGVIKVLRFYKKSKDTWRIEFTCGFRAIKKLNEILKDYWSALDAMPNKNPPLS 266
HVK+T ++G +++ S RIE A++ + L++ D + N
Sbjct: 654 HVKNTAQIGSFYIVKESGVSAGVRRIEAVVSKAALEFVKNQLEELSKVKDELKN------ 707
Query: 267 ERVREVLESVESLEEKVDSMRKEVWKWKEESLLGRSIEIGHYNVVTFVEKWDIKDAQAFA 326
++L ++ L+ ++ S++ E+ + L ++I+ V V++ D D +A
Sbjct: 708 ---NDILSGIKKLKNEILSLKNELKNSSKTELDSKNIQ----GVEICVKRIDNGDIKAMI 760
Query: 327 VDFVKNNPGTIVVL----ASEDYVILARNEEVEVSMKSLLEDLIKEFGGKGGGTDNLA 380
DF KN V+L E + A ++V + +L+++ + GG GGG D+ A
Sbjct: 761 DDF-KNKFAKAVILLIQVKDEKITLAAGVKDVPLKAGALVKEAAQILGGNGGGRDDFA 817
>emb|CAB93381.1| (AL357523) alanine tRNA synthetase [Streptomyces coelicolor A3(2)]
Length = 890
Score = 83.1 bits (202), Expect = 5e-15
Identities = 87/381 (22%), Positives = 156/381 (40%), Gaps = 19/381 (4%)
Query: 20 SDLTIKGDKIEVSLTETIFYPRGGGQPGDKGKIRGD-GFEIIVEDTVER-DGEIWHVGKL 77
S +GD++E+ L T FY GGGQ GD G+IR D G I V D + G H G +
Sbjct: 487 SPAATEGDEVEIVLDRTPFYAEGGGQIGDTGRIRVDTGAVIEVRDCQKPVPGVYVHKGVV 546
Query: 78 NGRTPEVGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRYDLDTSGFNIFGDYAKIEVN 137
VG + + +D R + H+ H+ L+ + + +
Sbjct: 547 QVGEVTVGAKAQASIDDRRRKAIARAHSATHLTHQALRDALGPTAAQAGSENQPGRFRFD 606
Query: 138 ----GELNWEMIEEAELEANKVIIDDLPVRVEEYEVLPKGVVEKLRKYIPNIKGKIRIVR 193
+ ++ + E + N+V+ DL VR + + + ++ ++R+V
Sbjct: 607 FGSPSAVPTAVMTDVEQKINEVLARDLDVRADVMGIDEAKKQGAIAEFGEKYGERVRVVT 666
Query: 194 IGENFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFTCGFRAIKKLNEILKDYWS 253
IG+ F CGGTHV +T ++G++K+L RIE G A L
Sbjct: 667 IGD-FSKELCGGTHVHNTAQLGLVKLLGESSIGSGVRRIEALVGVDAYSFLAREHTVVAQ 725
Query: 254 ALDAMPNKNPPLSERVREVLESVESLEEKVDSMRKEVWKWKEESLLGRSIEIGHYNVVT- 312
+ + + L E+V +L ++ E++++ R E L + ++ +VT
Sbjct: 726 LQELIKGRPEELPEKVSAMLGKLKDAEKEIEKFRAEKVLQAAGGLADSAKDVRGVALVTG 785
Query: 313 -FVEKWDIKDAQAFAVDF---VKNNPGTIVVLAS----EDYVILARNE---EVEVSMKSL 361
+ D + +D ++ +V L + + ++A NE E + L
Sbjct: 786 QVPDGTTADDLRKLVLDVRGRIQGGRAAVVALFTTVNGKPLTVIATNEAARERGLKAGDL 845
Query: 362 LEDLIKEFGGKGGGTDNLARG 382
+ K GG GGG ++A+G
Sbjct: 846 VRTAAKTLGGGGGGKPDVAQG 866
>pir||G82310 alanyl-tRNA synthetase VC0545 [imported] - Vibrio cholerae (group
O1 strain N16961) >gi|9654973|gb|AAF93713.1| (AE004140)
alanyl-tRNA synthetase [Vibrio cholerae]
Length = 860
Score = 78.8 bits (191), Expect = 1e-13
Identities = 93/389 (23%), Positives = 159/389 (39%), Gaps = 53/389 (13%)
Query: 17 AKISDLTIKGDKIEVSLTETIFYPRGGGQPGDKGKIRGDGFEIIVEDTVERDGEIWHVGK 76
A++S L+ GDK + L T FY GGQ GD G ++ D VEDT + I H G
Sbjct: 477 AEVSTLSA-GDKAIIVLDNTPFYAESGGQCGDTGVLKTDAGIFHVEDTQKLGNAIAHHGV 535
Query: 77 LNGRTPEVGEEVELELDWEWRYGNMQMHTGQHILSAVLKK----------------RYDL 120
+ G++V+ +D + R H+ H+L A L+K
Sbjct: 536 IAQGVLATGDQVDAIVDEKRRAAISLNHSATHLLHAALRKVLGEHVAQKGSLVRAETLRF 595
Query: 121 DTSGFNIFGDYAKIEVNGELNWEMIEEAELEANKVIIDDLPVRVEEYEVLPKGVVEKL-R 179
D S EV +N E+ +E N + ID E KG +
Sbjct: 596 DFSHLEAMTAAEIKEVERLVNQEVRRNHSIETNIMNID---------EAKAKGAMALFGE 646
Query: 180 KYIPNIKGKIRIVRIGENFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFTCGFR 239
KY ++R++ +G+ F CGG H +T ++G+ K++ + RIE G
Sbjct: 647 KY----DDQVRVLSMGD-FSTELCGGIHASNTGDIGLFKIISEGGIAAGIRRIEAVTGEG 701
Query: 240 AIKKLNEILKDYWSALDAMPNKNPPLSERVREVLESVESLEEKVDSMRKEVWKWKEESLL 299
A+ DY A A + +V E+ + LE+++ ++ ++ + L+
Sbjct: 702 AL--------DYLDAQQAQHD------AKVSEMAAKAKLLEKEIQQLKDKLAAKESAGLI 747
Query: 300 GRSIEIGHYNVVTFVEKWDIKDAQAFAVDFVKNNPGTIVVL---ASEDYVILARNEEVEV 356
+ +I NV+ A VD +KN + +++ +E V L ++
Sbjct: 748 NQVKQIAGVNVLVAQLNGADNKALRGMVDDLKNQLSSGIIMLGNVAEGKVGLIAGVTNDL 807
Query: 357 SMKSLLEDLIK----EFGGKGGGTDNLAR 381
+ K +L+ + GGKGGG ++A+
Sbjct: 808 TNKVKAGELVNMVALQVGGKGGGRPDMAQ 836
>sp|P21894|SYA_BOMMO ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|68535|pir||SYMTAT alanine--tRNA ligase (EC 6.1.1.7)
- silkworm >gi|155955|gb|AAA27821.1| (M55993) transfer
RNA-Ala synthetase [Bombyx mori]
Length = 967
Score = 78.0 bits (189), Expect = 2e-13
Identities = 77/310 (24%), Positives = 136/310 (43%), Gaps = 30/310 (9%)
Query: 12 LKTAKAKISDLTIKGDKIEVSLTETIFYPRGGGQPGDKG---KIRGDGFEIIVEDTVERD 68
L+ K +S+++ G + V L T FY GGQ D+G KI + E V++ +
Sbjct: 512 LRKNKEFVSEIS-SGQECGVILDRTSFYAEQGGQIFDEGYMVKIDDETVEFTVKNVQVKG 570
Query: 69 GEIWHVGKLNGRTPEVGEEVELELDWEWRYGNMQMHTGQHILSAVLKK--RYDLDTSGFN 126
G + H GK+ G +VG+ + L +D E R M HTG H+L+ VL+K D D G
Sbjct: 571 GYVLHAGKVEGIL-KVGDTLSLHIDTERRRLVMNNHTGTHVLNNVLRKVLGNDSDQRGSL 629
Query: 127 IFGDYAKIEV--NGELNWEMIEEAELEANKVIIDDLPVRVEEYEVLPKGVVEKLR-KYIP 183
+ D + + G + + I++ E E ++I + V + + LR +
Sbjct: 630 VMPDRLRFDFTNKGPMTIKQIKDTENEIKEIIAKNKTVYANYTSLSEAKKINGLRAMFDE 689
Query: 184 NIKGKIRIVRIG---ENFDLTP------------CGGTHVKSTREVGVIKVLRFYKKSKD 228
+ +R+V +G E+ P CGG+H+ T +G ++ +K
Sbjct: 690 HYPDPVRVVSVGVPVEDLIKNPDAPTGFETSVEFCGGSHLHRTSHIGEYVIVSEEGIAKG 749
Query: 229 TWRIEFTCG---FRAIKKLNEILKDYWSALDAMPNKNPPLSERVREVLESVESLEEKVDS 285
RI G +AI KL+ + + + + + +N +S +EV + + L ++
Sbjct: 750 IRRIVAVTGPEAIKAINKLSVLENEVNNVANFIKEQNESISH--KEVSKKIVDLTNEISQ 807
Query: 286 MRKEVWKWKE 295
+ WK E
Sbjct: 808 AQISYWKKDE 817
>emb|CAC11640.1| (AL445064) conserved hypothetical protein [Thermoplasma
acidophilum]
Length = 237
Score = 76.5 bits (185), Expect = 5e-13
Identities = 64/212 (30%), Positives = 105/212 (49%), Gaps = 9/212 (4%)
Query: 30 EVSLTETIFYPRGGGQPGDKGKIRGDGFEIIVEDTVERDGEIWHVGKLNGRTPE--VGEE 87
++ + ++IFYP G+P D GK+ DG E + DT+ DGE H+ ++ P+ VG+
Sbjct: 27 DMKVDQSIFYPTTFGEPNDTGKVIIDGKEYQIVDTI-YDGEYIHLISMD-TYPQTVVGKT 84
Query: 88 VELELDWEWRYGNMQMHTGQHILSAVLKKRYDLDTSGFNIFGDYAKIEV-NGELNWEMIE 146
V+ ++DW+ RY +M+ T I+S + ++ + + D A I++ ++ + I
Sbjct: 85 VKQKIDWDKRYIHMRFRTALRIISGLAYAKWKVSCRVNETYDDRAWIDIEKPDITEDEIN 144
Query: 147 EAELEANKVIIDDLPVRVEEYEVLPKGVVEKLRK---YIPNIKGKIRIVRIGENFDLTPC 203
E EAN V+ DL VR + E L+K + + +IRI+ I E P
Sbjct: 145 EIMAEANDVVKKDLDVRFRYIGLEDFNRSEDLKKMSIHDAYDEDRIRIMSI-EGLPDQPE 203
Query: 204 GGTHVKSTREVGVIKVLRFYKKSKDTWRIEFT 235
G +VK T EVG I K K + R+ T
Sbjct: 204 FGVNVKKTGEVGQINYKTTKLKGKISNRVNIT 235
>sp|Q9ZCA4|SYA_RICPR ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|7437635|pir||H71647 alanine--tRNA ligase (EC
6.1.1.7) (alaS) RP856 - Rickettsia prowazekii
>gi|3861381|emb|CAA15280.1| (AJ235273) ALANYL-TRNA
SYNTHETASE (alaS) [Rickettsia prowazekii]
Length = 877
Score = 76.1 bits (184), Expect = 7e-13
Identities = 77/262 (29%), Positives = 118/262 (44%), Gaps = 20/262 (7%)
Query: 35 ETIFYPRGGGQPGDKGKIRGDGFEIIVEDTVER-DGEIWHVGKLNGRTPEVGEEVELELD 93
+T FY GGQ GD G I G EI V DT + I H L +GE L ++
Sbjct: 497 QTPFYGESGGQMGDIGMIFSQGSEIEVIDTFKYLRSIIVHKCILKKGKINIGENANLNIN 556
Query: 94 WEWRYGNMQMHTGQHILSAVLKKRYDLDT--SGFNIFGDYAKIEVNGE--LNWEMIEEAE 149
+R H+ HIL AVL K G + Y + ++N + + I E
Sbjct: 557 IRYRQNLRIHHSATHILHAVLHKILGKQVIQKGSLVTSTYLRFDINHSKAITNQEITLIE 616
Query: 150 LEANKVIIDDLPVRVEEY---EVLPKGVVEKL-RKYIPNIKGKIRIVRIGENFDLTPCGG 205
+ N++I ++ V + + +G + KY ++R+V+IGE L C G
Sbjct: 617 DQVNEIIRNNHEVTTTVMFTEDAIKQGAIALFGEKY----DSEVRVVKIGET-SLELCCG 671
Query: 206 THVKSTREVGVIKVLRFYKKSKDTWRIEFTCGFRAIKKLNE---ILKDYWSALDAMPNKN 262
THVK T ++G K++ + RIE CG IK + E +LK S+ NKN
Sbjct: 672 THVKRTGDIGSFKIISESAIAAGVRRIEAVCGEFVIKLIRERDSLLKSIESSFKT--NKN 729
Query: 263 PPLSERVREVLESVESLEEKVD 284
L +V +LE + LE++++
Sbjct: 730 -ELITKVINILERNKELEKELE 750
>gb|AAF45874.1| (AE003427) CG10802 gene product [Drosophila melanogaster]
Length = 297
Score = 75.3 bits (182), Expect = 1e-12
Identities = 66/230 (28%), Positives = 114/230 (48%), Gaps = 24/230 (10%)
Query: 9 DPYLKTAKAKIS-------DLTIKGDKIE------VSLTETIFYPRGGGQPGDKGKIRGD 55
D +LK K KI D T K+E V +TI +P GGGQP D G +
Sbjct: 8 DSFLKEFKTKIVSSEFATLDWTDPSGKVEKLKGFNVICEDTILFPEGGGQPCDYGTL--G 65
Query: 56 GFEIIVEDTVERDGEIWHVGKLNGRTPEVGEEVELELDWEWRYGNMQMHTGQHILSAVLK 115
GF + V+R G + + E EV L LD++ R +MQ H+GQH+++A+
Sbjct: 66 GFPV---KNVQRKGSTAVHFVESPTSFEQDAEVLLTLDYQRRLDHMQQHSGQHLITALFD 122
Query: 116 KRYDLDTSGFNIFG--DYAKIEVNGELNWEMIEEAELEANKVIID--DLPVRVEEYEVLP 171
+ + DT+ +++ Y ++ ++ E ++ E +AN +I + ++ V + + EV
Sbjct: 123 REFKYDTTSWSLGSTVSYIQLSTPHLISRESLDLIERQANDLIREGREVTVLLVDPEVAQ 182
Query: 172 KGVVEKLRKYIP-NIKGKIRIVRIGENFDLTPCGGTHVKSTREVGVIKVL 220
+ + + +P + +G R+VRI E + C GTHV + ++ IK+L
Sbjct: 183 EFQDARAPRGLPKDHEGLARVVRI-EGIESNMCCGTHVTNLSQLQCIKLL 231
>pir||F75289 alanyl-tRNA synthetase - Deinococcus radiodurans (strain R1)
>gi|6460111|gb|AAF11848.1|AE002062_1 (AE002062)
alanyl-tRNA synthetase [Deinococcus radiodurans]
Length = 890
Score = 74.9 bits (181), Expect = 2e-12
Identities = 85/384 (22%), Positives = 159/384 (41%), Gaps = 32/384 (8%)
Query: 26 GDKIEVSLTETIFYPRGGGQPGDKGKIRGDGFEIIVEDTVE-RDGEIWHVGKLNGRTPEV 84
G + V L++T FY GGG+ GD G++ DG IV DT + + G H + +
Sbjct: 500 GSEATVVLSQTPFYGEGGGEVGDTGRLEWDGGAGIVRDTQKTKQGVFLHDVLVEQGELKE 559
Query: 85 GEEVELELDWEWRYGNMQMHTGQHILSAVLKKRY--DLDTSGFNIFGDYAKIEVN--GEL 140
G V + E R + HT H+L A L+ + G + D + + + +
Sbjct: 560 GTRVRGVVSPE-RAAIQRHHTATHLLHAALRAVLGGGVQQKGSRVAADQLRFDFSHGAAM 618
Query: 141 NWEMIEEAELEANKVIIDDLPVRVEEYEVLPKGVVEKLRKYIPNIKGKIRIVRIGENFD- 199
+ E I + E ++ + + PV E + + +R+VR+ + D
Sbjct: 619 SAEEIAQVETLVSRWVSANFPVSWREMPIAEAKAAGATALFGEKYGDVVRVVRVEGDVDF 678
Query: 200 -------LTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFTCGFRAIKKLNEILKDYW 252
+ CGG HV T ++G ++ + RIE G +A L L
Sbjct: 679 GGHAVSSMELCGGAHVSRTGDIGAFVIVSDENVAAGVRRIEALAGEQATAWLRGRLNASA 738
Query: 253 SALDAMPNKNPPLSERVREVLESVESLEEKVDSMRKEVWKWKEESLLG------RSIEIG 306
A + L ERV + +++ E++ R+++ E+ +G ++ E+G
Sbjct: 739 KAAALLNTSPEGLEERVSGLQGQLKAAEKETAQARRQL----AEAQMGGGGSAAQTRELG 794
Query: 307 HYNVVTF----VEKWDIKDAQAFAVDFVKNNPGTIVVLASEDYVILARNEEVEVSMKS-- 360
+ V + +E +++ A +D ++ +V+ + + V+ A + V +
Sbjct: 795 GFKVASLKLSGIEGNELRGAADKLLD--QSGADLVVIASDKGLVVKATKDAVAKGAHAGQ 852
Query: 361 LLEDLIKEFGGKGGGTDNLARGKI 384
L+ L GGKGGG ++A+ I
Sbjct: 853 LVSKLAAAGGGKGGGRPDMAQAGI 876
>sp|P27866|SYA_RHIME ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
Length = 887
Score = 74.1 bits (179), Expect = 3e-12
Identities = 88/388 (22%), Positives = 166/388 (42%), Gaps = 50/388 (12%)
Query: 25 KGDKIEVSLTETIFYPRGGGQPGDKGKIRGDGFEIIVEDTVER-DGEIWHVGKLNGRTPE 83
KG+ +++ L +T FY GGQ GD G I + ++ V DT +R +G H + + +
Sbjct: 484 KGENVQLVLNQTPFYGESGGQVGDTGVITTETGKLTVTDTQKRGEGLFVHYCTVEEGSVK 543
Query: 84 VGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRYDLDTS--GFNIFGDYAKIEVN--GE 139
GE L +D R H+ H+L L++ + G + + + +V+
Sbjct: 544 TGEAAALTVDHARRARLRANHSATHLLHEALREVLGTHVAQKGSLVAPERLRFDVSHPKP 603
Query: 140 LNWEMIEEAELEANKVIIDDLPVRVEEYEVLPKGVVEKLRKYIPNIKGKIRIVRIGEN-- 197
+ E ++ E AN++I+ + PV V + + ++R+V +G+
Sbjct: 604 MTAEELKIVEEMANEIIVQNTPVVTRLMSVDDAIAEGAMALFGEKYGDEVRVVSMGQGLR 663
Query: 198 -------FDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFTCGFRA---IKKLNEI 247
+ + CGGTHV +T ++G+++V+ R+E G A + + +E
Sbjct: 664 GSKAGKPYSVELCGGTHVSATGDIGLVRVVSESAVGAGVRRVEALTGEAARAYLGEQDER 723
Query: 248 LKDYWSALDAMPNKNPPLSERVREVLESVESLEEKVDSMRKEVWKWKEESLLGRSIEIGH 307
+K +AL P +VL VE+L ++ + +E+ + K++ L + G
Sbjct: 724 VKTLAAALKVQP----------ADVLGRVEALLDERRKLERELTEAKKKLALAGDGQNGS 773
Query: 308 YN-------------VVTFVEKWDIKDAQAFAVDFVKNNPGTIVVLA-----SEDYVILA 349
+ VV+ VE KD ++ A D K+ +V + ++A
Sbjct: 774 GDAARDIGGVRFLGRVVSGVEP---KDLKSLADDGKKSLGSGVVAFVGVSGDGKASAVVA 830
Query: 350 RNEEV--EVSMKSLLEDLIKEFGGKGGG 375
+++ +VS L+ GGKGGG
Sbjct: 831 VTDDLTSKVSAVDLVRVASAALGGKGGG 858
>sp|P70865|SYA_BARBA ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|1568622|gb|AAB09037.1| (U68242) AlaS [Bartonella
bacilliformis]
Length = 886
Score = 73.7 bits (178), Expect = 3e-12
Identities = 87/382 (22%), Positives = 167/382 (42%), Gaps = 41/382 (10%)
Query: 26 GDKIEVSLTETIFYPRGGGQPGDKGKIRGDGFEIIVEDTVERDGEIW-HVGKLNGRTPEV 84
G K + + +T FY GGQ GD G I G F V DT ++ ++ H+G++ +
Sbjct: 485 GQKAMIVVNQTPFYGESGGQVGDSGIISGANFIFEVHDTQKKGDNVFIHIGEIKTGQAKK 544
Query: 85 GEEVELELDWEWRYGNMQMHTGQHILSAVLKKRY--DLDTSGFNIFGDYAKIEVN--GEL 140
+ VEL +D R H+ H+L L++ + G + D + + + +
Sbjct: 545 HDCVELIVDSARRRKIRANHSATHLLHESLRQTLGSHVVQKGSFVSPDRLRFDFSHPKSI 604
Query: 141 NWEMIEEAELEANKVIIDDLPVRVEEYEVLPKGVVEKLRKYIPNIKGKIRIVRIGENFDL 200
+ E +++ E AN +++ + V + + + ++R++ +G N +
Sbjct: 605 SSEELKKIEDLANDIVLQNSKVTTRLMAIDDAIAEGAMALFGEKYGDEVRVISMGNNLEQ 664
Query: 201 TP---------CGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFTCGFRAIKKLNEILKDY 251
T CGGTHV+ T ++G+I ++ + RIE A L+ +
Sbjct: 665 TGSKKWWSIELCGGTHVQRTGDIGLIHIISETSVAAGVRRIEALTATAARLYLHGQDRRV 724
Query: 252 WSALDAMPNKNPPLSERVREVLESVESLEEKVDSMRKEVWKWKEESLLGRSI----EIGH 307
+ + + ERV+ +L+ LE++++ RK++ +L G S+ +I
Sbjct: 725 YEIAGLLKTSPADVQERVQTLLDERRKLEKELNDSRKKI------ALNGGSVNSQGDIQT 778
Query: 308 YNVVTF----VEKWDIKDAQAFAVDFVKNNPGTIVVL---ASED---YVILARNEEVEVS 357
N ++F V KD +A VD K G+ VV SED ++ +++ +
Sbjct: 779 INGISFMGGVVSNILPKDLKAL-VDSGKKKIGSGVVAFISVSEDGKGSAVVGVTDDLTDT 837
Query: 358 MKSLLEDLIK----EFGGKGGG 375
+ ++ DL++ GG+GGG
Sbjct: 838 LNAV--DLVRIISVTLGGQGGG 857
>sp|Q9ZJY5|SYA_HELPJ ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|7437615|pir||F71842 alanine--tRNA ligase (EC
6.1.1.7) - Helicobacter pylori (strain J99)
>gi|4155760|gb|AAD06738.1| (AE001543) ALANYL-TRNA
SYNTHETASE [Helicobacter pylori J99]
Length = 847
Score = 72.6 bits (175), Expect = 8e-12
Identities = 89/365 (24%), Positives = 162/365 (44%), Gaps = 35/365 (9%)
Query: 28 KIEVSLTETIFYPRGGGQPGDKGKIRGDGFEI-IVEDTVERDGEIWHVGKLNGRTPEVGE 86
++ V L +T FY GGG GD+G + D E +V DT G + + ++ + + G+
Sbjct: 479 EVWVLLEKTPFYAEGGGAIGDRGTLFKDNEEAALVLDTKNFFGLNFSLLEIK-KALKKGD 537
Query: 87 EVELELDWEWRYGNMQMHTGQHILSAVLKKRYDLDTSGFNIFGDYAKIEVNGE----LNW 142
+V ++ E R + H+ H+L + L++ S + ++ + LN
Sbjct: 538 QVIAQVSDE-RLEIAKHHSATHLLQSALREVLGSHVSQAGSLVESKRLRFDFSHAKALND 596
Query: 143 EMIEEAELEANKVIIDDLPVRVEEY---EVLPKGVVEKL-RKYIPNIKGKIRIVRIGENF 198
E +E+ E N I L +VE + KG + KY N+ R+V E
Sbjct: 597 EELEKVEDLVNAQIFKHLTSQVEHMPLNQAKDKGALALFSEKYAENV----RVVSFKEA- 651
Query: 199 DLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFTCG---FRAIKKLNEILKDYWSAL 255
+ CGG HV++T +G ++++ S RIE CG ++ K+ N+ LK+ + L
Sbjct: 652 SIELCGGIHVENTGLIGGFRIVKESGVSSGVRRIEAVCGKAFYQLTKEENKELKNAKTLL 711
Query: 256 DAMPNKNPPLSERVREVLESVESLEEKVDSMRKEVWKWKEESLLGRSIEIGHYNVVTFVE 315
KN + + ++ ESV++ ++ SM V K +L+ +E G ++ ++
Sbjct: 712 -----KNNDVIAGINKLKESVKNSQKAPVSMDLPVEKIHGVNLVVGVVEQG--DIKEMID 764
Query: 316 KWDIKDAQAFAVDFVKNNPGTIVVLASEDYVILARNEEVEVSMKSLLEDLIKEFGGKGGG 375
+ K + A+ F K N E + + V + + ++ + GGKGGG
Sbjct: 765 RLKSKHEKLLAIVFKKEN---------ERITLACGVKNVPIKANAWANEVAQILGGKGGG 815
Query: 376 TDNLA 380
D+ A
Sbjct: 816 RDDFA 820
>gb|AAF52657.1| (AE003621) Aats-ala gene product [Drosophila melanogaster]
Length = 966
Score = 72.2 bits (174), Expect = 1e-11
Identities = 60/251 (23%), Positives = 113/251 (44%), Gaps = 25/251 (9%)
Query: 19 ISDLTIKGDKIEVSLTETIFYPRGGGQPGDKG---KIRGDGFEIIVEDTVERDGEIWHVG 75
++++T G K + L +T FY GGQ D+G K+ + E +V+ R G I H+G
Sbjct: 518 VNEIT-SGQKAGIVLDKTNFYAESGGQIYDQGALVKVNDEANEFLVDRVYNRGGYILHIG 576
Query: 76 KLNGRTPEVGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRYDLDT--SGFNIFGDYAK 133
+ G T +VG+E+EL +D E R+ M+ H+ H L+ L + DT G + + +
Sbjct: 577 VVEG-TLKVGDELELHIDVERRWLTMKNHSATHALNHCLLQVLGKDTEQKGSLVVPEKLR 635
Query: 134 IEVNGE--LNWEMIEEAELEANKVIIDDLPVRVEEYEVLPKGVVEKLRKYIPNI-KGKIR 190
+ N + + E + + E +++ ++P+ +E ++ + LR + +R
Sbjct: 636 FDFNSKAAMTIEQVSKTEQLTKEMVYKNVPIYAKESKLALAKKIRGLRSVFDEVYPDPVR 695
Query: 191 IV---------------RIGENFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFT 235
++ GE + CGGTH++ + + + +K RI
Sbjct: 696 VISFGVPVDELEQNPDSEAGEQTSVEFCGGTHLRRSGHIMDFVISSEEAIAKGIRRIVAL 755
Query: 236 CGFRAIKKLNE 246
G A+K L +
Sbjct: 756 TGPEALKALKK 766
>pir||C82844 alanyl-tRNA synthetase XF0124 [imported] - Xylella fastidiosa
(strain 9a5c) >gi|9104908|gb|AAF82937.1|AE003866_2
(AE003866) alanyl-tRNA synthetase [Xylella fastidiosa]
Length = 916
Score = 72.2 bits (174), Expect = 1e-11
Identities = 88/393 (22%), Positives = 171/393 (43%), Gaps = 34/393 (8%)
Query: 19 ISDLTIKGDKIEVSLTETIFYPRGGGQPGDKGKIRG-DGFEIIVEDTVERDGEIW-HVGK 76
++D GD++ V T FY GGQ GD G + DG + V DT + G+ HV +
Sbjct: 517 LTDSASVGDEVIVLTDRTPFYAESGGQVGDIGTLMASDGVRLEVTDTQKLMGQFHGHVAR 576
Query: 77 LNGRTPEVGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRYDLDT--SGFNIFGDYAKI 134
+ +VG+ + + R H+ H+L L+ + G + D +
Sbjct: 577 IVQGGVKVGDVLSGSVAVARRKMVALNHSATHLLHCALRSVFGTHVVQKGSLVAPDRLRF 636
Query: 135 EVNGELNWEMIEEAELEANKVIIDDLPVRVEEYEVLPK-GVVEKLRKYIPNIKGK----- 188
+ + ++E I A++ + +++D VR ++ + G+ L + G+
Sbjct: 637 DFS---HFEPIAAAQMTLIERMVND-EVRANHLVMIEQMGMQAALDAGAMALFGEKYGEH 692
Query: 189 IRIVRIGENFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFTCGFRAIKKLNEIL 248
+R+V +G + +L CGGTH+ T ++G+ K++ S RIE G A LN +L
Sbjct: 693 VRVVTMGTSVEL--CGGTHINRTGDIGLFKIISECGVSSGVRRIEAVTGESA---LNHVL 747
Query: 249 KD---YWSALDAMPNKNPPLSERVREVLESVESLEEKVDSMRKEVWKWKEESLLGRSIEI 305
+ + + + + +R++ + ++LE +++ ++ ++ LL ++ +
Sbjct: 748 AEEHRLYEVAGLIGSNANDVVNHIRQLTDRQKTLERELEKLKGKLISGTITDLLSTAVNV 807
Query: 306 GHYNVVTFVEKWDIKDAQAF--AVDFVK-NNPGTIVVLASED-------YVILARNEEVE 355
VV + D D +A A+D +K ++VLA + R +
Sbjct: 808 ADVKVV--AARLDGLDGKALREALDRLKLQLSDAVIVLAGVTGGKVALVTAVNGRRAMGK 865
Query: 356 VSMKSLLEDLIKEFGGKGGGTDNLARGKIEAEP 388
V +LL + + G+GGG + A+G E P
Sbjct: 866 VKADTLLSHVATQINGRGGGRVDFAQGGGEDGP 898
>gb|AAC49007.1| (U18672) cytoplasmic alanyl-tRNA synthetase [Saccharomyces
cerevisiae] >gi|1097386|prf||2113423A Ala-tRNA
synthetase [Saccharomyces cerevisiae]
Length = 958
Score = 71.8 bits (173), Expect = 1e-11
Identities = 101/438 (23%), Positives = 182/438 (41%), Gaps = 63/438 (14%)
Query: 19 ISDLTIKGDKIEVSLTETIFYPRGGGQPGDKGKIR-GDGFEIIVEDTVERDGEIWHVGKL 77
+ ++T G K + L +T FY GGQ D GKI D E VE+ +G ++H G L
Sbjct: 514 VDEITEPGKKYGIILDKTCFYAEQGGQEYDTGKIVIDDAAEFNVENVQLYNGFVFHTGSL 573
Query: 78 NGRTPEVGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRY--DLDTSGFNIFGDYAKIE 135
VG+++ D R+ HTG HIL+ LK+ D+D G + + + +
Sbjct: 574 EEGKLSVGDKIIASFDELRRFPIKNNHTGTHILNFALKETLGNDVDQKGSLVAPEKLRFD 633
Query: 136 VNGE--LNWEMIEEAELEANKVIIDDLPVRVEEYEV-LPKGVVEKLRKYIPNIKGKIRIV 192
+ + ++ E +++ E N+ I ++L V +E + L K + + +R+V
Sbjct: 634 FSHKKAVSNEELKKVEDICNEQIKENLQVFYKEIPLDLAKSIDGVRAVFGETYPDPVRVV 693
Query: 193 RIGE---------------NFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFTCG 237
+G+ + + CGGTHV T ++ +L +K RI G
Sbjct: 694 SVGKPIEELLANPANEEWTKYSIEFCGGTHVNKTGDIKYFVILEESGIAKGIRRIVAVTG 753
Query: 238 FRAIKKLNEILKDYWSALDA------MPNKNPPLSE-------------RVREVLESVES 278
A + + + + + LDA P K L E E+ +
Sbjct: 754 TEAF-EAQRLAEQFAADLDAADKLPFSPIKEKKLKELGVKLGQLSISVITKNELKQKFNK 812
Query: 279 LEEKV-DSMRKEVWKWKEESL-----LGRSIEIGHYNVVTFVEKWDIKDAQAFAVDFVKN 332
+E+ V D ++ K +++L ++ E Y +V F++ A A++++K+
Sbjct: 813 IEKAVKDEVKSRAKKENKQTLDEVKTFLQTNENAPY-LVKFIDISPNAKAITEAINYMKS 871
Query: 333 NPG----TIVVLASED---------YVILARNEEVEVSMKSLLEDLIKEFGGKGGGTDNL 379
N +I +LA D Y+ A + + +L + + GGK GG N+
Sbjct: 872 NDSVKDKSIYLLAGNDPEGRVAHGCYISNAALAK-GIDGSALAKKVSSIIGGKAGGKGNV 930
Query: 380 ARGKIEAEPEDVIDFVVD 397
+G + +P + D V D
Sbjct: 931 FQG-MGDKPAAIKDAVDD 947
>gi|6324911 Cytoplasmic alanyl-tRNA synthetase gene; Ala1p [Saccharomyces
cerevisiae] >gi|1711623|sp|P40825|SYAC_YEAST ALANYL-TRNA
SYNTHETASE, CYTOPLASMIC (ALANINE--TRNA LIGASE) (ALARS)
>gi|2118342|pir||S62065 alanine--tRNA ligase (EC
6.1.1.7), cytosolic - yeast (Saccharomyces cerevisiae)
>gi|1163069|emb|CAA89980.1| (Z49821) ALA1 [Saccharomyces
cerevisiae] >gi|1420729|emb|CAA99658.1| (Z75243) ORF
YOR335c [Saccharomyces cerevisiae]
Length = 958
Score = 71.8 bits (173), Expect = 1e-11
Identities = 101/438 (23%), Positives = 181/438 (41%), Gaps = 63/438 (14%)
Query: 19 ISDLTIKGDKIEVSLTETIFYPRGGGQPGDKGKIR-GDGFEIIVEDTVERDGEIWHVGKL 77
+ ++T G K + L +T FY GGQ D GKI D E VE+ +G ++H G L
Sbjct: 514 VDEITEPGKKYGIILDKTCFYAEQGGQEYDTGKIVIDDAAEFNVENVQLYNGFVFHTGSL 573
Query: 78 NGRTPEVGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRY--DLDTSGFNIFGDYAKIE 135
VG+++ D R+ HTG HIL+ LK+ D+D G + + + +
Sbjct: 574 EEGKLSVGDKIIASFDELRRFPIKNNHTGTHILNFALKETLGNDVDQKGSLVAPEKLRFD 633
Query: 136 VNGE--LNWEMIEEAELEANKVIIDDLPVRVEEYEV-LPKGVVEKLRKYIPNIKGKIRIV 192
+ + ++ E +++ E N+ I ++L V +E + L K + + +R+V
Sbjct: 634 FSHKKAVSNEELKKVEDICNEQIKENLQVFYKEIPLDLAKSIDGVRAVFGETYPDPVRVV 693
Query: 193 RIGE---------------NFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFTCG 237
+G+ + + CGGTHV T ++ +L +K RI G
Sbjct: 694 SVGKPIEELLANPANEEWTKYSIEFCGGTHVNKTGDIKYFVILEESGIAKGIRRIVAVTG 753
Query: 238 FRAIKKLNEILKDYWSALDA------MPNKNPPLSE-------------RVREVLESVES 278
A + + + + + LDA P K L E E+ +
Sbjct: 754 TEAF-EAQRLAEQFAADLDAADKLPFSPIKEKKLKELGVKLGQLSISVITKNELKQKFNK 812
Query: 279 LEEKV-DSMRKEVWKWKEESL-----LGRSIEIGHYNVVTFVEKWDIKDAQAFAVDFVKN 332
+E+ V D ++ K +++L + E Y +V F++ A A++++K+
Sbjct: 813 IEKAVKDEVKSRAKKENKQTLDEVKTFFETNENAPY-LVKFIDISPNAKAITEAINYMKS 871
Query: 333 NPG----TIVVLASED---------YVILARNEEVEVSMKSLLEDLIKEFGGKGGGTDNL 379
N +I +LA D Y+ A + + +L + + GGK GG N+
Sbjct: 872 NDSVKDKSIYLLAGNDPEGRVAHGCYISNAALAK-GIDGSALAKKVSSIIGGKAGGKGNV 930
Query: 380 ARGKIEAEPEDVIDFVVD 397
+G + +P + D V D
Sbjct: 931 FQG-MGDKPAAIKDAVDD 947
>gb|AAD53924.1|AF179611_8 (AF179611) alanyl-tRNA synthetase [Zymomonas mobilis]
Length = 888
Score = 71.4 bits (172), Expect = 2e-11
Identities = 62/259 (23%), Positives = 121/259 (45%), Gaps = 22/259 (8%)
Query: 25 KGDKIEVSLTETIFYPRGGGQPGDKGKIRGDG-FEIIVEDTVERDGEIW-HVGKLNGRTP 82
+GD I + +T FY GGQ GD G I G+ ++ V DT + G I H+ K+
Sbjct: 483 QGDDITIITNQTPFYGESGGQKGDIGVITGNNDLKMTVTDTQKPLGRIHAHIAKIEKGEI 542
Query: 83 EVGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRYDLDTS--GFNIFGDYAKIEVNGE- 139
++G++++L++D R H+ H+L A L+ + S G + + + + + +
Sbjct: 543 KIGDDIQLQVDINHRNRLRANHSATHLLHAALRDQLGQHVSQKGSMVSAERLRFDFSHQK 602
Query: 140 -LNWEMIEEAELEANKVIIDDLPVRVEEYEVLPKGVVE--KLRKYIPNIKGKIRIVRIG- 195
L+ + + E E N+ I+++ V + P+ VE + + ++R++ +G
Sbjct: 603 ALSDQELAAIEAEVNQQILNNSVVTTR--LMTPESAVEAGAMALFGEKYGNEVRVLSMGS 660
Query: 196 --------ENFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFTCGFRA---IKKL 244
++ + CGGTHV + ++G+ ++ S RIE G A +
Sbjct: 661 CLNDQNEESSWSVELCGGTHVSALGQIGLFHIVSETAVSSGIRRIEAVTGEEARLWLVGR 720
Query: 245 NEILKDYWSALDAMPNKNP 263
+ +L++ S L A+P + P
Sbjct: 721 DRLLRETASILKAVPEEVP 739
>gb|AAF05594.1|AF188719_1 (AF188719) alanyl-tRNA synthetase [Giardia intestinalis]
Length = 969
Score = 70.2 bits (169), Expect = 4e-11
Identities = 75/266 (28%), Positives = 127/266 (47%), Gaps = 38/266 (14%)
Query: 5 LYYVDPY----LKTAKAKISDLTI------KGDKIEVSLTETIFYPRGGGQPGDKGKIR- 53
+YY PY K A AK+ + KG + V L +T+FYP GGQ D G ++
Sbjct: 532 VYYTKPYGEKLRKLADAKVVSIFANMEDKSKGRNL-VILDKTVFYPTSGGQQHDTGVLKF 590
Query: 54 --GDGFEIIVEDTVERDGEIWH--VGKLNGRTPEV---GEEVELELDWEWRYGNMQMHTG 106
G+G ++I+ D V+ ++ H + +LN + G V + +D R M HT
Sbjct: 591 LLGNG-KMIIHDVVDVR-KVGHCVMHELNAPVADSIVQGTSVSMAIDSARRDQLMCHHTA 648
Query: 107 QHILSAVLKKRYDLDT--SGFNIFGDYAKIEVNGELNWEMIEEA--ELEANKVIIDDLPV 162
H++ A K +G + A +++ + EE E EAN++I D++P+
Sbjct: 649 AHVIHATANKVLGPHVWQAGAKKTTEVATLDITHYRSLTFDEERAIEREANRMIRDNIPI 708
Query: 163 RVEEYEVLPKGVVEKLRKY-------IPNIKGKIRIVRIGENFDLTPCGGTHVKSTREVG 215
R +Y+ LPK EK + +P +R V I ++ D C GTH+ +T ++G
Sbjct: 709 R--KYQ-LPKNKAEKKYGFSLYQGGVVPG--STVRCVDITDH-DTEACCGTHLDNTGKIG 762
Query: 216 VIKVLRFYKKSKDTWRIEFTCGFRAI 241
+I++++ + S R+ F G RA+
Sbjct: 763 LIRIVKSTRISDGVVRLTFVAGERAL 788
>gb|AAG23137.1|AF245445_1 (AF245445) alanyl-tRNA synthetase [Giardia intestinalis]
Length = 954
Score = 70.2 bits (169), Expect = 4e-11
Identities = 75/266 (28%), Positives = 127/266 (47%), Gaps = 38/266 (14%)
Query: 5 LYYVDPY----LKTAKAKISDLTI------KGDKIEVSLTETIFYPRGGGQPGDKGKIR- 53
+YY PY K A AK+ + KG + V L +T+FYP GGQ D G ++
Sbjct: 517 VYYTKPYGEKLRKLADAKVVSIFANMEDKSKGRNL-VILDKTVFYPTSGGQQHDTGVLKF 575
Query: 54 --GDGFEIIVEDTVERDGEIWH--VGKLNGRTPEV---GEEVELELDWEWRYGNMQMHTG 106
G+G ++I+ D V+ ++ H + +LN + G V + +D R M HT
Sbjct: 576 LLGNG-KMIIHDVVDVR-KVGHCVMHELNAPVADSIVQGTSVSMAIDSARRDQLMCHHTA 633
Query: 107 QHILSAVLKKRYDLDT--SGFNIFGDYAKIEVNGELNWEMIEEA--ELEANKVIIDDLPV 162
H++ A K +G + A +++ + EE E EAN++I D++P+
Sbjct: 634 AHVIHATANKVLGPHVWQAGAKKTTEVATLDITHYRSLTFDEERAIEREANRMIRDNIPI 693
Query: 163 RVEEYEVLPKGVVEKLRKY-------IPNIKGKIRIVRIGENFDLTPCGGTHVKSTREVG 215
R +Y+ LPK EK + +P +R V I ++ D C GTH+ +T ++G
Sbjct: 694 R--KYQ-LPKNEAEKKYGFSLYQGGVVPG--STVRCVDITDH-DTEACCGTHLDNTGKIG 747
Query: 216 VIKVLRFYKKSKDTWRIEFTCGFRAI 241
+I++++ + S R+ F G RA+
Sbjct: 748 LIRIVKSTRISDGVVRLTFVAGERAL 773
>sp|P56452|SYA_HELPY ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|7437616|pir||A64675 alanine--tRNA ligase (EC
6.1.1.7) - Helicobacter pylori (strain 26695)
>gi|2314404|gb|AAD08285.1| (AE000629) alanyl-tRNA
synthetase (alaS) [Helicobacter pylori 26695]
Length = 847
Score = 69.9 bits (168), Expect = 5e-11
Identities = 88/365 (24%), Positives = 161/365 (44%), Gaps = 35/365 (9%)
Query: 28 KIEVSLTETIFYPRGGGQPGDKGKIRGDGFEI-IVEDTVERDGEIWHVGKLNGRTPEVGE 86
++ V L +T FY GGG GD+G + D E+ IV DT G + + ++ + + G+
Sbjct: 479 EVWVLLEKTPFYAEGGGAIGDRGALFKDNGEVAIVLDTKNFFGLNFSLLEIK-KALKKGD 537
Query: 87 EVELELDWEWRYGNMQMHTGQHILSAVLKKRYDLDTSGFNIFGDYAKIEVNGE----LNW 142
+V ++ E R+ + H+ H+L + L++ S + ++ + LN
Sbjct: 538 QVIAQVSDE-RFEIAKHHSATHLLQSALREVLGSHVSQAGSLVESKRLRFDFSHAKALND 596
Query: 143 EMIEEAELEANKVIIDDLPVRVEEY---EVLPKGVVEKL-RKYIPNIKGKIRIVRIGENF 198
E +E+ E N I L +VE + KG + KY N+ R+V E
Sbjct: 597 EELEKVEDLVNAQIFKHLNSQVEHMPLNQAKDKGALALFSEKYAENV----RVVSFKEA- 651
Query: 199 DLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIEFTCG---FRAIKKLNEILKDYWSAL 255
+ CGG HV++T +G ++++ S RIE CG ++ K+ N+ LK+ + L
Sbjct: 652 SIELCGGIHVENTGLIGGFRIVKESGVSSGVRRIEAVCGKAFYQLAKEENKELKNAKTLL 711
Query: 256 DAMPNKNPPLSERVREVLESVESLEEKVDSMRKEVWKWKEESLLGRSIEIGHYNVVTFVE 315
KN + + ++ ESV++ ++ SM V K +L+ +E G ++ ++
Sbjct: 712 -----KNNDVIAGINKLKESVKNSQKAPVSMDLPVEKIHGVNLVVGVVEQG--DIKEMID 764
Query: 316 KWDIKDAQAFAVDFVKNNPGTIVVLASEDYVILARNEEVEVSMKSLLEDLIKEFGGKGGG 375
+ K + A+ F K N E + + + ++ + GGKGGG
Sbjct: 765 RLKSKHERLLAMVFKKEN---------ERITLACGVKNAPIKANVWANEVAQILGGKGGG 815
Query: 376 TDNLA 380
+ A
Sbjct: 816 RGDFA 820
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.316 0.139 0.405
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 161802542
Number of Sequences: 2977
Number of extensions: 7426140
Number of successful extensions: 23815
Number of sequences better than 1.0e-10: 61
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 59
Number of HSP's that attempted gapping in prelim test: 23660
Number of HSP's gapped (non-prelim): 64
length of query: 405
length of database: 189,106,746
effective HSP length: 56
effective length of query: 349
effective length of database: 155,591,474
effective search space: 54301424426
effective search space used: 54301424426
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.6 bits)
S2: 166 (69.1 bits)