BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB1200 (purQ) DE:phosphoribosylformylglycinamidine synthase I
(EC 6.3.5.3) (purQ)
(223 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||B75026 phosphoribosylformylglycinamidine synthase (EC 6.3.5... 460 e-129
pir||C71211 probable phosphoribosylformylglycinamidine synthase ... 399 e-110
pir||F64505 phosphoribosylformylglycinamidine synthase (EC 6.3.5... 260 1e-68
pir||C70395 phosphoribosyl formylglycinamidine synthase I - Aqui... 245 3e-64
sp|P12041|PURQ_BACSU PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE ... 234 6e-61
emb|CAB57673.1| (Y18930) phosphoribosylformylglycinamidine synth... 233 1e-60
gb|AAK40939.1| Phosphoribosylformylglycinamidine synthase I (FGA... 233 1e-60
pir||T51700 phosphoribosylformylglycinamidine synthase (EC 6.3.5... 228 5e-59
dbj|BAB04347.1| (AP001509) phosphoribosylformylglycinamidine syn... 227 1e-58
pir||E69091 phosphoribosylformylglycinamidine synthase (EC 6.3.5... 219 2e-56
pir||D75545 phosphoribosylformylglycinamidine synthase I - Deino... 215 5e-55
pir||G72276 phosphoribosylformylglycinamidine synthase I - Therm... 213 2e-54
pir||S76655 phosphoribosylformylglycinamidine synthase (EC 6.3.5... 210 2e-53
gb|AAG20128.1| (AE005091) phosphoribosylformylglycinamide syntha... 199 2e-50
pir||C81397 phosphoribosylformylglycinamidine synthase (EC 6.3.5... 190 1e-47
pir||G70709 probable purQ protein - Mycobacterium tuberculosis (... 183 1e-45
emb|CAB56358.1| (AL118514) phosphoribosyl formylglycinamidine sy... 182 4e-45
emb|CAB08429.1| (Z95151) PurQ [Mycobacterium leprae] 180 1e-44
dbj|BAA89450.1| (AB003162) 5'-phosphoribosyl-N-formylglycinamidi... 180 1e-44
emb|CAC12439.1| (AL445067) phosphoribosylformylglycinamidine syn... 157 8e-38
gi|11498859 phosphoribosylformylglycinamidine synthase I (purQ) ... 157 1e-37
sp|P35421|PUR4_DROME PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE ... 96 5e-19
gb|AAF52329.1| (AE003612) ade2 gene product [Drosophila melanoga... 96 5e-19
gb|AAF31730.1|AC020579_7 (AC020579) putative phosphoribosylformy... 89 3e-17
pir||H64090 phosphoribosylformylglycinamidine synthase (EC 6.3.5... 87 2e-16
sp|P43847|PURL_HAEIN PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE ... 87 2e-16
sp|P15254|PURL_ECOLI PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE ... 87 2e-16
pir||SYECPG phosphoribosylformylglycinamidine synthase (EC 6.3.5... 87 2e-16
gb|AAB08888.1| (U68728) phosphoribosylformylglycinamidine synthe... 85 9e-16
dbj|BAA20816.1| (AB002359) KIAA0361 [Homo sapiens] 84 1e-15
pir||A82272 phosphoribosylformylglycinamidine synthase VC0869 [i... 84 1e-15
pir||B83175 phosphoribosylformylglycinamidine synthase PA3763 [i... 83 3e-15
pir||G81017 phosphoribosylformylglycinamidine synthase NMB1996 [... 76 3e-13
pir||G81961 phosphoribosylformylglycinamidine synthase (EC 6.3.5... 76 3e-13
pir||D82685 phosphoribosylformylglycinamidine synthetase XF1423 ... 72 7e-12
gi|6321498 5'-phosphoribosylformyl glycinamidine synthetase; Ade... 70 2e-11
pir||T11661 phosphoribosylformylglycinamidine synthase (EC 6.3.5... 70 2e-11
>pir||B75026 phosphoribosylformylglycinamidine synthase (EC 6.3.5.3) I PAB1200 -
Pyrococcus abyssi (strain Orsay)
>gi|5459162|emb|CAB50648.1| (AJ248288)
phosphoribosylformylglycinamidine synthase I (EC
6.3.5.3) (purQ) [Pyrococcus abyssi]
Length = 223
Score = 460 bits (1170), Expect = e-129
Identities = 223/223 (100%), Positives = 223/223 (100%)
Query: 1 MPRFAVIVFPGTNCDFETVEAIRKAGGEAERVWYKESIREYDGVVLPGGFSYADYLRAGA 60
MPRFAVIVFPGTNCDFETVEAIRKAGGEAERVWYKESIREYDGVVLPGGFSYADYLRAGA
Sbjct: 1 MPRFAVIVFPGTNCDFETVEAIRKAGGEAERVWYKESIREYDGVVLPGGFSYADYLRAGA 60
Query: 61 IAARQRIMEEVREFAEEGRPVLGICNGFQVLTEAGLLPGALRPNKIPRFICKWIYLKVND 120
IAARQRIMEEVREFAEEGRPVLGICNGFQVLTEAGLLPGALRPNKIPRFICKWIYLKVND
Sbjct: 61 IAARQRIMEEVREFAEEGRPVLGICNGFQVLTEAGLLPGALRPNKIPRFICKWIYLKVND 120
Query: 121 TNTAFTQLYEEGEIIRMPIAHAEGNYYVDDPSRIRIVFQYSDENGNLTEEANPNGSVMNI 180
TNTAFTQLYEEGEIIRMPIAHAEGNYYVDDPSRIRIVFQYSDENGNLTEEANPNGSVMNI
Sbjct: 121 TNTAFTQLYEEGEIIRMPIAHAEGNYYVDDPSRIRIVFQYSDENGNLTEEANPNGSVMNI 180
Query: 181 AGVSNEGGNVLGMMPHPERASDAFLGSEDGLKVFRSMVEYAKR 223
AGVSNEGGNVLGMMPHPERASDAFLGSEDGLKVFRSMVEYAKR
Sbjct: 181 AGVSNEGGNVLGMMPHPERASDAFLGSEDGLKVFRSMVEYAKR 223
>pir||C71211 probable phosphoribosylformylglycinamidine synthase I - Pyrococcus
horikoshii >gi|3258399|dbj|BAA31082.1| (AP000007) 227aa
long hypothetical phosphoribosylformylglycinamidine
synthase I [Pyrococcus horikoshii]
Length = 227
Score = 399 bits (1014), Expect = e-110
Identities = 180/223 (80%), Positives = 211/223 (93%)
Query: 1 MPRFAVIVFPGTNCDFETVEAIRKAGGEAERVWYKESIREYDGVVLPGGFSYADYLRAGA 60
M +FAVIVFPGTNCDFETVEAI++AGGEAERVWYK+S+++YDGVV+PGGFSYADYLRAGA
Sbjct: 5 MVKFAVIVFPGTNCDFETVEAIKRAGGEAERVWYKQSVKDYDGVVIPGGFSYADYLRAGA 64
Query: 61 IAARQRIMEEVREFAEEGRPVLGICNGFQVLTEAGLLPGALRPNKIPRFICKWIYLKVND 120
IAARQ++MEE+RE AEEGRP+LGICNGFQ+LTEA LLPGALRPNKIPRF+CKW++LKV D
Sbjct: 65 IAARQKVMEEIRELAEEGRPILGICNGFQILTEANLLPGALRPNKIPRFLCKWVHLKVVD 124
Query: 121 TNTAFTQLYEEGEIIRMPIAHAEGNYYVDDPSRIRIVFQYSDENGNLTEEANPNGSVMNI 180
T FT LYEEGE++RMPIAHAEGNYY+D+PS++RIVFQYSDE G++TEEANPNGSV+NI
Sbjct: 125 VETPFTYLYEEGEVVRMPIAHAEGNYYIDNPSKVRIVFQYSDEKGSITEEANPNGSVLNI 184
Query: 181 AGVSNEGGNVLGMMPHPERASDAFLGSEDGLKVFRSMVEYAKR 223
AGV+N+ GNVLGMMPHPERASD FLGSEDGLKVF+S+VE+ K+
Sbjct: 185 AGVTNKQGNVLGMMPHPERASDRFLGSEDGLKVFKSIVEWMKK 227
>pir||F64505 phosphoribosylformylglycinamidine synthase (EC 6.3.5.3) I -
Methanococcus jannaschii >gi|1592231|gb|AAB99669.1|
(U67605) phosphoribosylformylglycinamidine synthase I,
(purQ) [Methanococcus jannaschii]
Length = 230
Score = 260 bits (657), Expect = 1e-68
Identities = 123/228 (53%), Positives = 165/228 (71%), Gaps = 7/228 (3%)
Query: 3 RFAVIVFPGTNCDFETVEAIRKAGGEAERVWY-KESIREYDGVVLPGGFSYADYLRAGAI 61
+ AV F GTNCD + A++ AGGE E V++ +E++ Y G V+PGGFSY DYLRAGAI
Sbjct: 2 KIAVTKFLGTNCDLDVCHAVKLAGGEPELVFFTQENLDSYKGAVIPGGFSYGDYLRAGAI 61
Query: 62 AARQRIMEEVREFAEEGRPVLGICNGFQVLTEAGLLPGALRPNKIPRFICKWIYLKVNDT 121
+AR I++ +++ EEG+PVLGICNG Q+ EAG G L N +FICKW+Y++V +
Sbjct: 62 SARTPIIKGLKKMVEEGKPVLGICNGAQIGLEAGFSKGTLTNNLNAKFICKWVYIRVENN 121
Query: 122 NTAFTQLYEEGEIIRMPIAHAEGNYYVDDPS------RIRIVFQYSDENGNLTEEANPNG 175
T FTQ Y++GE++++PIAHAEG +Y DD + IVF+Y DE G +TEEANPNG
Sbjct: 122 KTPFTQYYKKGEVLKIPIAHAEGRFYADDETLDYMYKNNMIVFKYCDETGEVTEEANPNG 181
Query: 176 SVMNIAGVSNEGGNVLGMMPHPERASDAFLGSEDGLKVFRSMVEYAKR 223
S+ NIAGV NE N + +MPHPERAS+ LGS+DGLK+F+ M++YAKR
Sbjct: 182 SIDNIAGVCNENQNCVLLMPHPERASEKILGSDDGLKMFKGMIDYAKR 229
>pir||C70395 phosphoribosyl formylglycinamidine synthase I - Aquifex aeolicus
>gi|2983574|gb|AAC07146.1| (AE000723) phosphoribosyl
formylglycinamidine synthase I [Aquifex aeolicus]
Length = 227
Score = 245 bits (620), Expect = 3e-64
Identities = 119/224 (53%), Positives = 163/224 (72%), Gaps = 8/224 (3%)
Query: 3 RFAVIVFPGTNCDFETVEAIRKA-GGEAERV-WYKESIREYDGVVLPGGFSYADYLRAGA 60
+FAV VFPG+NCD++T IR + E V W ++++ +YD VVLPGGFS+ DYLR GA
Sbjct: 2 KFAVCVFPGSNCDYDTYYVIRDILEKDVEFVYWEEKNLSKYDVVVLPGGFSFGDYLRPGA 61
Query: 61 IAARQRIMEEVREFAEEGRPVLGICNGFQVLTEAGLLPGALRPNKIPRFICKWIYLKVND 120
+AAR + + + +FA++G+ V+GICNGFQ+LTE GLLPGAL PN RF+CKW+ L+V +
Sbjct: 62 LAARTPLAQAIYDFAQKGKYVIGICNGFQILTELGLLPGALLPNLNMRFVCKWVNLRVEN 121
Query: 121 TNTAFTQLYEEGEIIRMPIAHAEGNYYVDD------PSRIRIVFQYSDENGNLTEEANPN 174
+AFT+ E+G+++R+PIAH +G YYV + +I+F+Y DE G + EE NPN
Sbjct: 122 ERSAFTRKLEKGDVLRIPIAHHDGRYYVPEEELRKMEENGQILFRYCDEQGEVKEEVNPN 181
Query: 175 GSVMNIAGVSNEGGNVLGMMPHPERASDAFLGSEDGLKVFRSMV 218
GSV NIAGV N+ GNV GMMPHPERAS+ LGS DGL ++ S++
Sbjct: 182 GSVSNIAGVMNKEGNVFGMMPHPERASEDILGSHDGLMLWYSLL 225
>sp|P12041|PURQ_BACSU PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE I (FGAM SYNTHASE I)
>gi|68652|pir||SYBS1G phosphoribosylformylglycinamidine
synthase (EC 6.3.5.3) component I [validated] - Bacillus
subtilis >gi|143368|gb|AAA22678.1| (J02732)
phosphoribosylformyl glycinamidine synthetase I (PUR-L;
gtg start codon) [Bacillus subtilis]
>gi|2632961|emb|CAB12467.1| (Z99107)
phosphoribosylformylglycinamidine synthetase II
[Bacillus subtilis]
Length = 227
Score = 234 bits (591), Expect = 6e-61
Identities = 121/221 (54%), Positives = 156/221 (69%), Gaps = 9/221 (4%)
Query: 3 RFAVIVFPGTNCDFETVEAIR-KAGGEAERVWYKE-SIREYDGVVLPGGFSYADYLRAGA 60
+FAVIV PG+NCD + A++ + G E E VW++E S+ +DGV++PGGFSY DYLR GA
Sbjct: 2 KFAVIVLPGSNCDIDMYHAVKDELGHEVEYVWHEETSLDGFDGVLIPGGFSYGDYLRCGA 61
Query: 61 IAARQRIMEEVREFAEEGRPVLGICNGFQVLTEAGLLPGALRPNKIPRFICKWIYLKVND 120
IA IM V++ A EG+PVLG+CNGFQ+L E GLLPGA+R NK +FIC+ + L V +
Sbjct: 62 IARFANIMPAVKQAAAEGKPVLGVCNGFQILQELGLLPGAMRRNKDLKFICRPVELIVQN 121
Query: 121 TNTAFTQLYEEGEIIRMPIAHAEGNYYVDDPSRIRIVFQYSDENGNL--TEEANPNGSVM 178
T FT YE+GE I +P+AH EGN+Y DD + + EN + T +N NGSV
Sbjct: 122 DETLFTASYEKGESITIPVAHGEGNFYCDDETLATL-----KENNQIAFTYGSNINGSVS 176
Query: 179 NIAGVSNEGGNVLGMMPHPERASDAFLGSEDGLKVFRSMVE 219
+IAGV NE GNVLGMMPHPERA D LGS DGLK+F+S+V+
Sbjct: 177 DIAGVVNEKGNVLGMMPHPERAVDELLGSADGLKLFQSIVK 217
>emb|CAB57673.1| (Y18930) phosphoribosylformylglycinamidine synthase I [Sulfolobus
solfataricus]
Length = 224
Score = 233 bits (589), Expect = 1e-60
Identities = 120/223 (53%), Positives = 163/223 (72%), Gaps = 7/223 (3%)
Query: 5 AVIVFPGTNCDFETVEAIRKAGGEAERVWYKESIRE-YDGVVLPGGFSYADYLRAGAIAA 63
A+I FPGT C+ + +A+ +AG V YK+ + Y+GV+LPGGFS+ DYLRAG+IAA
Sbjct: 3 AIIKFPGTTCETDVYKALIEAGVPTVIVKYKDFDPDRYNGVILPGGFSFGDYLRAGSIAA 62
Query: 64 RQRIMEEVREFAEEGRPVLGICNGFQVLTEAGLLPGALRPNKIPRFICKWIYLKVNDTNT 123
M++V++ AE+G+ V+GICNGFQ+L E+GLL GAL PN RFI KW+YLKV +T
Sbjct: 63 STETMKKVKQMAEDGKIVIGICNGFQILVESGLLKGALLPNLKLRFISKWVYLKVIRADT 122
Query: 124 AFTQLYEEGEIIRMPIAHAEGNYYVD--DPSRIRIVFQYSDENGNLTEEANPNGSVMNIA 181
T+ ++ +IIRMPIAHAEG YYVD D ++ +V QY DENGN++E+ NPNGS++NIA
Sbjct: 123 ILTKGLDK-KIIRMPIAHAEGRYYVDDIDYAKTHMVLQYCDENGNISEDVNPNGSLLNIA 181
Query: 182 GVSNEGGNVLGMMPHPERAS---DAFLGSEDGLKVFRSMVEYA 221
++NE GNV+GMMPHPERAS + G+ DGL + R + E+A
Sbjct: 182 SIANEEGNVIGMMPHPERASFKLTSIDGTVDGLILLRRLGEWA 224
>gb|AAK40939.1| Phosphoribosylformylglycinamidine synthase I (FGAM synthase I)
(purQ) [Sulfolobus solfataricus]
Length = 224
Score = 233 bits (589), Expect = 1e-60
Identities = 120/223 (53%), Positives = 163/223 (72%), Gaps = 7/223 (3%)
Query: 5 AVIVFPGTNCDFETVEAIRKAGGEAERVWYKESIRE-YDGVVLPGGFSYADYLRAGAIAA 63
A+I FPGT C+ + +A+ +AG V YK+ + Y+GV+LPGGFS+ DYLRAG+IAA
Sbjct: 3 AIIKFPGTTCETDVYKALIEAGVPTVIVKYKDFDPDRYNGVILPGGFSFGDYLRAGSIAA 62
Query: 64 RQRIMEEVREFAEEGRPVLGICNGFQVLTEAGLLPGALRPNKIPRFICKWIYLKVNDTNT 123
M++V++ AE+G+ V+GICNGFQ+L E+GLL GAL PN RFI KW+YLKV +T
Sbjct: 63 STETMKKVKQMAEDGKIVIGICNGFQILVESGLLKGALLPNLKLRFISKWVYLKVIRADT 122
Query: 124 AFTQLYEEGEIIRMPIAHAEGNYYVD--DPSRIRIVFQYSDENGNLTEEANPNGSVMNIA 181
T+ ++ +IIRMPIAHAEG YYVD D ++ +V QY DENGN++E+ NPNGS++NIA
Sbjct: 123 ILTKGLDK-KIIRMPIAHAEGRYYVDDIDYAKTHMVLQYCDENGNISEDVNPNGSLLNIA 181
Query: 182 GVSNEGGNVLGMMPHPERAS---DAFLGSEDGLKVFRSMVEYA 221
++NE GNV+GMMPHPERAS + G+ DGL + R + E+A
Sbjct: 182 SIANEEGNVIGMMPHPERASFKLTSIDGTVDGLILLRRLGEWA 224
>pir||T51700 phosphoribosylformylglycinamidine synthase (EC 6.3.5.3) component I
[similarity] - Lactococcus lactis
>gi|4097532|gb|AAD12625.1| (U64311)
phosphoribosylformylglycinamidine synthetase I
[Lactococcus lactis]
Length = 226
Score = 228 bits (575), Expect = 5e-59
Identities = 117/225 (52%), Positives = 152/225 (67%), Gaps = 16/225 (7%)
Query: 3 RFAVIVFPGTNCDFETVEAIRKA-GGEAERVWYKE-SIREYDGVVLPGGFSYADYLRAGA 60
+FAVI FPG+NCDF+ + AIR G EAE VW+ E S+ +DGV++PGGFSY DYLR GA
Sbjct: 2 KFAVIQFPGSNCDFDLLWAIRDVMGAEAEFVWHDEKSLAGFDGVLIPGGFSYGDYLRCGA 61
Query: 61 IAARQRIMEEVREFAEEGRPVLGICNGFQVLTEAGLLPGALRPNKIPRFICKWIYLKVND 120
IA+ IM E++ A+EG+PV G CNGFQ+L E+GLLPG L N+ +F+ KW LKV +
Sbjct: 62 IASFANIMPEIKRLAKEGKPVFGTCNGFQILVESGLLPGVLIRNEGLKFVSKWQVLKVEN 121
Query: 121 TNTAFTQLYEEGEIIRMPIAHAEGNYYVDDPSRI------RIVFQYSDENGNLTEEANPN 174
+ FT Y + +I +PIAH EG Y D+ + +IVF Y+DE NPN
Sbjct: 122 NQSNFTTEYAKDALINLPIAHGEGQYVADEATLAELKENGQIVFTYADE--------NPN 173
Query: 175 GSVMNIAGVSNEGGNVLGMMPHPERASDAFLGSEDGLKVFRSMVE 219
GSV NIAG+ N+ GNVLGMMPHPERA + LG DG K+F S+++
Sbjct: 174 GSVENIAGIINKEGNVLGMMPHPERAMEELLGGADGRKMFASLLK 218
>dbj|BAB04347.1| (AP001509) phosphoribosylformylglycinamidine synthetase II
[Bacillus halodurans]
Length = 227
Score = 227 bits (572), Expect = 1e-58
Identities = 116/224 (51%), Positives = 155/224 (68%), Gaps = 17/224 (7%)
Query: 3 RFAVIVFPGTNCDFETVEAIRKA-GGEAERVWYKE-SIREYDGVVLPGGFSYADYLRAGA 60
+FAVIVFPG+NCD + A++ A G E + +W+ E S+ YD ++LPGGFSY DYLR+G+
Sbjct: 2 KFAVIVFPGSNCDADMYHAVKDALGEEVDYLWHTETSVEGYDAILLPGGFSYGDYLRSGS 61
Query: 61 IAARQRIMEEVREFAEEGRPVLGICNGFQVLTEAGLLPGALRPNKIPRFICKWIYLKVND 120
IA IME+V A EG PVLG+CNGFQVL EAGLLPGA+ N+ FICK + L+V +
Sbjct: 62 IARFSPIMEDVIRAANEGVPVLGVCNGFQVLLEAGLLPGAMLRNEKLTFICKPVELEVQN 121
Query: 121 TNTAFTQLYEEGEIIRMPIAHAEGNYYVDD------PSRIRIVFQYSDENGNLTEEANPN 174
+T FT YE+GE I +P+AH EGNYY DD + ++VF+Y+D N
Sbjct: 122 NDTFFTSEYEQGETITIPVAHGEGNYYCDDETLKQLEANNQVVFRYTD---------RVN 172
Query: 175 GSVMNIAGVSNEGGNVLGMMPHPERASDAFLGSEDGLKVFRSMV 218
GS +IAG+ N+ GNVLGMMPHPERA + +G EDGL++F+S++
Sbjct: 173 GSRNHIAGIVNKAGNVLGMMPHPERAVEQLVGGEDGLRLFKSIL 216
>pir||E69091 phosphoribosylformylglycinamidine synthase (EC 6.3.5.3) I -
Methanobacterium thermoautotrophicum (strain Delta H)
>gi|2621210|gb|AAB84674.1| (AE000804)
phosphoribosylformylglycinamidine synthase I
[Methanobacterium thermoautotrophicum]
Length = 218
Score = 219 bits (553), Expect = 2e-56
Identities = 110/223 (49%), Positives = 145/223 (64%), Gaps = 13/223 (5%)
Query: 3 RFAVIVFPGTNCDFETVEAIRKAGGEAERVWYKE-SIREYDGVVLPGGFSYADYLRAGAI 61
R VI FPG+NCD + + AG E E VW+ + ++ D VV+PGGFSY DYLRAGAI
Sbjct: 2 RVGVIRFPGSNCDRDVHHVLELAGAEPEYVWWNQRNLDHLDAVVIPGGFSYGDYLRAGAI 61
Query: 62 AARQRIMEEVREFAEEGRPVLGICNGFQVLTEAGLLPGALRPNKIPRFICKWIYLKVNDT 121
AA +M+ VRE E +PVLGICNG Q+L E GL+PG N+ P+F C+W L+V T
Sbjct: 62 AAITPVMDAVRELVREEKPVLGICNGAQILAEVGLVPGVFTVNEHPKFNCQWTELRVKTT 121
Query: 122 NTAFTQLYEEGEIIRMPIAHAEGNYYVDDPSRI----RIVFQYSDENGNLTEEANPNGSV 177
T FT L+++ E+IRMP+AHAEG YY D+ S + ++V Q+ E NPNGS+
Sbjct: 122 RTPFTGLFKKDEVIRMPVAHAEGRYYHDNISEVWENDQVVLQFHGE--------NPNGSL 173
Query: 178 MNIAGVSNEGGNVLGMMPHPERASDAFLGSEDGLKVFRSMVEY 220
I GV +E G V +MPHPERAS+ LGS DG K FR ++++
Sbjct: 174 DGITGVCDESGLVCAVMPHPERASEEILGSVDGFKFFRGILKF 216
>pir||D75545 phosphoribosylformylglycinamidine synthase I - Deinococcus
radiodurans (strain R1)
>gi|6457894|gb|AAF09809.1|AE001884_4 (AE001884)
phosphoribosylformylglycinamidine synthase I
[Deinococcus radiodurans]
Length = 266
Score = 215 bits (541), Expect = 5e-55
Identities = 118/222 (53%), Positives = 148/222 (66%), Gaps = 18/222 (8%)
Query: 5 AVIVFPGTNCDFETVEAIRKAGGE-AERVWYKESI--REYDGVVLPGGFSYADYLRAGAI 61
AVI FPG+NCD + + A R + A+ VW+ E+ + V LPGGFSY D+LR+GAI
Sbjct: 49 AVIQFPGSNCDADALHAARLLLDDGAQFVWHTETALPEGTELVFLPGGFSYGDHLRSGAI 108
Query: 62 AARQRIMEEVREFAEEGRPVLGICNGFQVLTEAGLLPGALRPNKIPRFICKWIYLKVNDT 121
AAR IM V+ AE G VLG+CNGFQVLTEAGLLPGAL NK F+CK ++L+V +
Sbjct: 109 AARSPIMNAVKAHAEAGGYVLGVCNGFQVLTEAGLLPGALSRNKELHFMCKPVHLRVENN 168
Query: 122 NTAFTQLYEEGEIIRMPIAHAEGNYYVDDPSRI------RIVFQYSDENGNLTEEANPNG 175
T F++ Y G+II +PIAH EGNYY D + R+VF+Y+D NPNG
Sbjct: 169 ATDFSRAYGPGQIIEIPIAHGEGNYYADAATIAELEEGGRVVFRYAD---------NPNG 219
Query: 176 SVMNIAGVSNEGGNVLGMMPHPERASDAFLGSEDGLKVFRSM 217
S+ +IAG+ NE GNVLGMMPHPERA + LGSEDG VF S+
Sbjct: 220 SLNDIAGIVNERGNVLGMMPHPERAVELLLGSEDGKGVFESL 261
>pir||G72276 phosphoribosylformylglycinamidine synthase I - Thermotoga maritima
(strain MSB8) >gi|4981800|gb|AAD36320.1|AE001780_4
(AE001780) phosphoribosylformylglycinamidine synthase I
[Thermotoga maritima]
Length = 213
Score = 213 bits (536), Expect = 2e-54
Identities = 107/223 (47%), Positives = 145/223 (64%), Gaps = 13/223 (5%)
Query: 2 PRFAVIVFPGTNCDFETVEAIRKAGGEAERVWYKESIREYDGVVLPGGFSYADYLRAGAI 61
PR V+V+PG+NCD + A+ G E V + + +Y+ ++LPGGFSY DYLR GA+
Sbjct: 3 PRACVVVYPGSNCDRDAYHALEINGFEPSYVGLDDKLDDYELIILPGGFSYGDYLRPGAV 62
Query: 62 AARQRIMEEVREFAEEGRPVLGICNGFQVLTEAGLLPGALRPNKIPRFICKWIYLKVNDT 121
AAR++I E+ + AE G+ ++GICNGFQ+L E GLL GAL N +FICKW+ L V +
Sbjct: 63 AAREKIAFEIAKAAERGKLIMGICNGFQILIEMGLLKGALLQNSSGKFICKWVDLIVENN 122
Query: 122 NTAFTQLYEEGEIIRMPIAHAEGNYY-VDDPSRIRIVFQYSDENGNLTEEANPNGSVMNI 180
+T FT +E+GE IR+PIAH G Y +DD + +V +Y + NGS I
Sbjct: 123 DTPFTNAFEKGEKIRIPIAHGFGRYVKIDD---VNVVLRYVKD---------VNGSDERI 170
Query: 181 AGVSNEGGNVLGMMPHPERASDAFLGSEDGLKVFRSMVEYAKR 223
AGV NE GNV G+MPHPERA + +G EDG KVF+S++ Y KR
Sbjct: 171 AGVLNESGNVFGLMPHPERAVEELIGGEDGKKVFQSILNYLKR 213
>pir||S76655 phosphoribosylformylglycinamidine synthase (EC 6.3.5.3) I -
Synechocystis sp. (strain PCC 6803)
>gi|1001761|dbj|BAA10599.1| (D64004) phosphoribosyl
formylglycinamidine synthase [Synechocystis sp.]
Length = 224
Score = 210 bits (528), Expect = 2e-53
Identities = 109/224 (48%), Positives = 145/224 (64%), Gaps = 8/224 (3%)
Query: 1 MPRFAVIVFPGTNCDFETVEAIRKAGGEAER-VWYKES-IREYDGVVLPGGFSYADYLRA 58
M F +IVFPG+NCD + + R +W++E+ + D VVLPGGFSY DYLR
Sbjct: 1 MTSFGIIVFPGSNCDRDIATVTAGLLDQPTRFIWHQETDLHGVDVVVLPGGFSYGDYLRC 60
Query: 59 GAIAARQRIMEEVREFAEEGRPVLGICNGFQVLTEAGLLPGALRPNKIPRFICKWIYLKV 118
GAIA IM + + A G+ VLGICNGFQVLTE GLLPGAL N+ FIC + ++V
Sbjct: 61 GAIARFSPIMTAIIDHANAGKRVLGICNGFQVLTEVGLLPGALIRNRDLHFICDRVTVRV 120
Query: 119 NDTNTAFTQLYEEGEIIRMPIAHAEGNYYVDDPS------RIRIVFQYSDENGNLTEEAN 172
T +T+ Y+ ++I +PIAH EG Y+ D + +I+F+YS+ G LT ++N
Sbjct: 121 ESNQTVWTKGYQSQQVITLPIAHGEGRYFADGDTLKALEDNEQILFRYSNAQGELTTDSN 180
Query: 173 PNGSVMNIAGVSNEGGNVLGMMPHPERASDAFLGSEDGLKVFRS 216
PNGS+ NIAG++N GNVLGMMPHPERA+D L + DGL +F S
Sbjct: 181 PNGSLHNIAGITNVQGNVLGMMPHPERAADRLLKATDGLAMFIS 224
>gb|AAG20128.1| (AE005091) phosphoribosylformylglycinamide synthase I; PurL2
[Halobacterium sp. NRC-1]
Length = 224
Score = 199 bits (502), Expect = 2e-50
Identities = 98/213 (46%), Positives = 140/213 (65%), Gaps = 7/213 (3%)
Query: 5 AVIVFPGTNCDFETVEAIRKAGGEAERVWYKESI-REYDGVVLPGGFSYADYLRAGAIAA 63
AV+ F G+NCD + V A+ G +A W+ + + + DGVV+PGGFSY DYLRAGA+AA
Sbjct: 4 AVVRFGGSNCDRDAVRALAHLGVDAAVAWHDDGLPADTDGVVVPGGFSYGDYLRAGAMAA 63
Query: 64 RQRIMEEVREFAEEGRPVLGICNGFQVLTEAGLLPGALRPNKIPRFICKWIYLKVNDTNT 123
+ ++ EVR A +G PVLG+CNG Q+ EAGL PGA N RF C+ ++L+V + T
Sbjct: 64 QSPVVAEVRALAADGVPVLGVCNGAQIGCEAGLAPGAFTTNASARFQCERVHLRVENATT 123
Query: 124 AFTQLYEEGEIIRMPIAHAEGNYYVDDPSRI------RIVFQYSDENGNLTEEANPNGSV 177
+T Y EG+++ +PIAH EG + +DD + R++F+Y + +G +TE ANPNGS
Sbjct: 124 PWTAAYSEGDVLEIPIAHGEGRFEIDDDAYADLVADDRVLFRYCNADGEVTEAANPNGST 183
Query: 178 MNIAGVSNEGGNVLGMMPHPERASDAFLGSEDG 210
+AGV+ + +V MMPHPERA+ LG+ DG
Sbjct: 184 GAVAGVTGDRDHVAVMMPHPERATLPALGATDG 216
>pir||C81397 phosphoribosylformylglycinamidine synthase (EC 6.3.5.3) I Cj0514
[imported] - Campylobacter jejuni (strain NCTC 11168)
>gi|6967983|emb|CAB75151.1| (AL139075)
phosphoribosylformylglycinamidine synthase I
[Campylobacter jejuni]
Length = 223
Score = 190 bits (477), Expect = 1e-47
Identities = 99/222 (44%), Positives = 139/222 (62%), Gaps = 15/222 (6%)
Query: 3 RFAVIVFPGTNCDFETVEAIRKAGGEAERVWYKESIREYDGVVLPGGFSYADYLRAGAIA 62
+ A+I FPGTNC+F+T A K G + + VW++E + D VVLPGGFSY DYLR AIA
Sbjct: 2 KVAIIRFPGTNCEFDTTYAFEKLGVKTQIVWHEEKEFDADLVVLPGGFSYGDYLRCAAIA 61
Query: 63 ARQRIMEEVREFAEEGRPVLGICNGFQVLTEAGLLPGALRPNKIPRFICKWIYLKVNDTN 122
M+ V A++G +LGICNGFQ+L E+GLL GA++ N FI K L+V +
Sbjct: 62 KLAPAMQGVFNHAKKGGYILGICNGFQILLESGLLKGAMKHNNNLSFISKNQSLRVVSND 121
Query: 123 TAFTQLYEEGEIIRMPIAHAEGNYYVDDPS------RIRIVFQYSDENGNLTEEANPNGS 176
AF + +++ EII +PIAH EGNYY D+ + + I+ +Y E NPNGS
Sbjct: 122 NAFLKNFKKDEIINLPIAHGEGNYYADETTLKELQDKDLIILKY---------EPNPNGS 172
Query: 177 VMNIAGVSNEGGNVLGMMPHPERASDAFLGSEDGLKVFRSMV 218
V +IAG+ +E + G+MPHPERA + LG++ GLK+ + +
Sbjct: 173 VFDIAGICDENKKIFGLMPHPERACEKVLGNDVGLKMLKGFL 214
>pir||G70709 probable purQ protein - Mycobacterium tuberculosis (strain H37RV)
>gi|1550666|emb|CAB02378.1| (Z80226) purQ [Mycobacterium
tuberculosis]
Length = 224
Score = 183 bits (460), Expect = 1e-45
Identities = 101/227 (44%), Positives = 139/227 (60%), Gaps = 21/227 (9%)
Query: 3 RFAVIVFPGTNCDFETVEAIRKAGGEAERVWYKES-IREYDGVVLPGGFSYADYLRAGAI 61
R V+ FPGT D + A R+ G E +W+ ++ ++ D VV+PGGFSY DYLRAGAI
Sbjct: 4 RIGVVTFPGTLDDVDAARAARQVGAEVVSLWHADADLKGVDAVVVPGGFSYGDYLRAGAI 63
Query: 62 AARQRIMEEVREFAEEGRPVLGICNGFQVLTEAGLLPGALRPNKIPRFICKWIYLKVNDT 121
A +M+EV A+ G PVLGICNGFQVL EAGLLPGAL N FIC+ ++L+V T
Sbjct: 64 ARFAPVMDEVVAAADRGMPVLGICNGFQVLCEAGLLPGALTRNVGLHFICRDVWLRVAST 123
Query: 122 NTAFTQLYEEGEIIRMPIAHAEGNYYVDDPSRI--------RIVFQYSDENGNLTEEANP 173
+TA+T +E + +P+ EG Y P ++ R+VF+Y D N
Sbjct: 124 STAWTSRFEPDADLLVPLKSGEGRYVA--PEKVLDELEGEGRVVFRYHD---------NV 172
Query: 174 NGSVMNIAGVSNEGGNVLGMMPHPERASDAFLG-SEDGLKVFRSMVE 219
NGS+ +IAG+ + G V+G+MPHPE A +A G S+DGL +F S ++
Sbjct: 173 NGSLRDIAGICSANGRVVGLMPHPEHAIEALTGPSDDGLGLFYSALD 219
>emb|CAB56358.1| (AL118514) phosphoribosyl formylglycinamidine synthase I (EC
6.3.5.3) [Streptomyces coelicolor A3(2)]
Length = 226
Score = 182 bits (456), Expect = 4e-45
Identities = 99/226 (43%), Positives = 141/226 (61%), Gaps = 17/226 (7%)
Query: 3 RFAVIVFPGTNCDFETVEAIRKAGGEAERVWYKES-IREYDGVVLPGGFSYADYLRAGAI 61
R V+ FPG+ D +T AIR AG E +W+K+ +++ D VVL GGFSY DYLRAGAI
Sbjct: 4 RIGVVTFPGSLDDRDTQRAIRVAGAEPVALWHKDKDLKQVDAVVLCGGFSYGDYLRAGAI 63
Query: 62 AARQRIMEEVREFAEEGRPVLGICNGFQVLTEAGLLPGALRPNKIPRFICKWIYLKVNDT 121
A +M+ V + A+ G PVLGICNGFQ+LTEA LLPG + N FIC+ L+V +
Sbjct: 64 ARFSPVMDTVIDQAKAGLPVLGICNGFQILTEAHLLPGGMLGNDHLHFICRDQKLRVENA 123
Query: 122 NTAFTQLYEEGEIIRMPIAHAEGNYYVDD------PSRIRIVFQYSDENGNLTEEANPNG 175
+T++T Y G+ I +P+ + +G Y D + R+ F+Y D NPNG
Sbjct: 124 DTSWTSDYTAGQEIHIPLKNMDGRYVADRRTLDELEAEGRVAFRYLD--------MNPNG 175
Query: 176 SVMNIAGVSNEGGNVLGMMPHPERASDAFLGS--EDGLKVFRSMVE 219
S+ +IAG++N GNV+G+MPHPE A ++ +G+ DGL F S+++
Sbjct: 176 SLNDIAGITNAAGNVVGLMPHPEHAVESLIGTGRTDGLPFFTSILK 221
>emb|CAB08429.1| (Z95151) PurQ [Mycobacterium leprae]
Length = 224
Score = 180 bits (453), Expect = 1e-44
Identities = 102/225 (45%), Positives = 135/225 (59%), Gaps = 17/225 (7%)
Query: 3 RFAVIVFPGTNCDFETVEAIRKAGGEAERVWYKES-IREYDGVVLPGGFSYADYLRAGAI 61
R VI FPGT D + A R G EA +W+ ++ ++ D VV+PGGFSY DYLRAGAI
Sbjct: 4 RIGVITFPGTLDDVDAARAARHVGAEAVSLWHADADLKGVDAVVVPGGFSYGDYLRAGAI 63
Query: 62 AARQRIMEEVREFAEEGRPVLGICNGFQVLTEAGLLPGALRPNKIPRFICKWIYLKVNDT 121
A IM EV + + G PVLGICNGFQVL EAGLLPGAL N FIC+ ++L+V T
Sbjct: 64 ARLSPIMTEVVDAVQRGMPVLGICNGFQVLCEAGLLPGALIRNVGLHFICRDVWLRVIST 123
Query: 122 NTAFTQLYEEGEIIRMPIAHAEGNYYVDD------PSRIRIVFQYSDENGNLTEEANPNG 175
+TA+T +E + + + EG Y + R+VF+Y D N NG
Sbjct: 124 STAWTSRFEPETDLLVSLKSGEGRYVASENVLDELDGEGRVVFRYHD---------NING 174
Query: 176 SVMNIAGVSNEGGNVLGMMPHPERASDAFLG-SEDGLKVFRSMVE 219
S+ +IAG+S+ G V+GMMPHPE A + G S+DGL +F S ++
Sbjct: 175 SLRDIAGISSANGRVVGMMPHPEHAIEVLTGPSDDGLGLFYSALD 219
>dbj|BAA89450.1| (AB003162) 5'-phosphoribosyl-N-formylglycinamidine synthetase
[Corynebacterium ammoniagenes]
Length = 225
Score = 180 bits (452), Expect = 1e-44
Identities = 101/225 (44%), Positives = 140/225 (61%), Gaps = 19/225 (8%)
Query: 3 RFAVIVFPGTNCDFETVEAIRKAGGEAERVWYKES-IREYDGVVLPGGFSYADYLRAGAI 61
+ VI FPGT D + A+R AG EA +W+ ++ ++ D VV+PGGFSY DYLR+GAI
Sbjct: 4 KIGVITFPGTLDDVDAQRAVRLAGAEAVSLWHADTDLKGVDAVVVPGGFSYGDYLRSGAI 63
Query: 62 AARQRIMEEVREFAEEGRPVLGICNGFQVLTEAGLLPGALRPNKIPRFICKWIYLKVNDT 121
+A +M+ V + A +G P LGICNGFQ+LTEAGLL GAL NK F C +L+V +
Sbjct: 64 SALAPVMQSVVDRARQGMPTLGICNGFQILTEAGLLEGALTRNKGLHFHCVDTHLEVVNN 123
Query: 122 NTAFTQLYEEGEIIRMPIAHAEGNYYVDDPSRI-------RIVFQYSDENGNLTEEANPN 174
NTA+T +E G+ I +P H EG + P I ++VF+Y+D N N
Sbjct: 124 NTAWTTEFEAGDKIFVPAKHGEGRFQA-APETIDKLEGEGQVVFRYTD---------NFN 173
Query: 175 GSVMNIAGVSNEGGNVLGMMPHPERASDAFLG-SEDGLKVFRSMV 218
GS+ +IAG++NE G ++G+MPHPE A + G S DGL +F S +
Sbjct: 174 GSLNDIAGITNETGRIVGLMPHPEHAIETLTGPSTDGLGLFVSAI 218
>emb|CAC12439.1| (AL445067) phosphoribosylformylglycinamidine synthase I related
protein [Thermoplasma acidophilum]
Length = 289
Score = 157 bits (394), Expect = 8e-38
Identities = 84/220 (38%), Positives = 136/220 (61%), Gaps = 23/220 (10%)
Query: 2 PRFAVIVFPGTNCDFETVEAIRKAGGEAERVWY------KESIREYDGVVLPGGFSYADY 55
P+ +++ GTN + E ++R++GG+ + V +++I +YD +++PGGFS DY
Sbjct: 36 PKVGILLMEGTNNETEVFFSVRRSGGDPDYVHVSDIAAGRKAISDYDALIVPGGFSAGDY 95
Query: 56 LRAGAIAARQRIM---EEVREFAEEGRPVLGICNGFQVLTEAGLLPG----ALRPNKIPR 108
+RAG I A + + +E+R+F + GRP++GICNGFQV+ E GL+ L N+ R
Sbjct: 96 IRAGVIFAARLLAVAGKEIRDFVDSGRPLIGICNGFQVIMEMGLIGKRDELTLTNNESGR 155
Query: 109 FICKWIYLKVNDTNTAFTQLYEEGEIIRMPIAHAEGNYYVDDPSRIR-------IVFQYS 161
F C++ Y+ + N F ++ ++P+AHAEG V S ++ ++F+YS
Sbjct: 156 FECRYTYITMTSDNPIFRDAFKGKGSFQVPVAHAEGRIAVSGVSVLKRLYENDQVLFKYS 215
Query: 162 DENGNLTEEA--NPNGSVMNIAGVSNEGGNVLGMMPHPER 199
D +G +T+E NPNGSV +IA ++NE GNV+G+MPHPER
Sbjct: 216 DTHG-VTDEYPWNPNGSVDSIASLTNEHGNVIGLMPHPER 254
>gi|11498859 phosphoribosylformylglycinamidine synthase I (purQ) [Archaeoglobus
fulgidus] >gi|7483916|pir||C69407
phosphoribosylformylglycinamidine synthase I (purQ)
homolog - Archaeoglobus fulgidus
>gi|2649319|gb|AAB89983.1| (AE001017)
phosphoribosylformylglycinamidine synthase I (purQ)
[Archaeoglobus fulgidus]
Length = 271
Score = 157 bits (393), Expect = 1e-37
Identities = 104/265 (39%), Positives = 140/265 (52%), Gaps = 45/265 (16%)
Query: 3 RFAVIVFPGTNCDFETVEAIRKAGGEAERVWYKE------------SIREYDGVVLPGGF 50
+ AV+ GTNC+ ETV+A R G EAE V K+ S+ +Y +V PGGF
Sbjct: 7 KVAVLRMEGTNCEDETVKAFRSLGVEAEAVHIKQFYSDMIRFEEQRSVFDYQCLVFPGGF 66
Query: 51 SYADYLRAGAI-AARQR--IMEEVREFAEEGRPVLGICNGFQVLTEAGLLPG-------- 99
S DY+RAGAI +AR + + +++ EF + G P+LGICNGFQVL E G LPG
Sbjct: 67 SAGDYIRAGAIFSARVKSVLRKDIEEFIKMGYPILGICNGFQVLVELGALPGFDEDKPLA 126
Query: 100 -----ALRPNKIPRFICKWIYLKVNDTNTAFTQLYEEGEIIRMPIAHAEG---------- 144
AL N RF C+ LK F + ++ +++ P+AHAEG
Sbjct: 127 EKPEMALAMNDSSRFECRPTLLKKESEKCIFVKNLKK-DVVMFPVAHAEGKVVFPSGKED 185
Query: 145 NYYVDDPSRIRIVFQYSDENGNLTEEA-NPNGSVMNIAGVSNEGGNVLGMMPHPERASDA 203
Y S +IVF+Y DE G+ NPNGS NIAG+ N V G+MPHPERA
Sbjct: 186 EYLERLTSNDQIVFRYVDEKGDYAGYPWNPNGSFYNIAGICNATHTVFGLMPHPERAFFG 245
Query: 204 FL-----GSEDGLKVFRSMVEYAKR 223
+ G DG +FRS+V+Y ++
Sbjct: 246 YQVGRREGYGDGYCIFRSVVDYLEK 270
>sp|P35421|PUR4_DROME PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE (FGAM SYNTHASE)
(FORMYLGLYCINAMIDE RIBOTIDE AMIDOTRANSFERASE) (FGARAT)
(ADENOSINE-2) (FGAMS) (FORMYLGLYCINAMIDE RIBOTIDE
SYNTHETASE) >gi|7438074|pir||T13363
phosphoribosylformylglycinamidine synthase (EC 6.3.5.3) -
fruit fly (Drosophila melanogaster)
>gi|414423|gb|AAC46468.1| (U00683) formylglycineamide
ribotide amidotransferase [Drosophila melanogaster]
Length = 1354
Score = 95.6 bits (234), Expect = 5e-19
Identities = 72/234 (30%), Positives = 104/234 (43%), Gaps = 33/234 (14%)
Query: 3 RFAVIVFPGTNCDFETVEAIRKAGGEAERVWYKE------SIREYDGVVLPGGFSYADYL 56
R AV+ G N + E + + +A E V + S+ +Y G++ PGGFSYAD L
Sbjct: 1086 RVAVLREEGVNSEREMMACLLRANFEVHDVTMSDLLQGTASVSQYRGLIFPGGFSYADTL 1145
Query: 57 R-----AGAIAARQRIMEEVREFAEEGRPV-LGICNGFQVLTEAGLLPGA---------- 100
A I R++ + F LGICNG Q++T G + A
Sbjct: 1146 GSAKGWAANILHNPRLLPQFEAFKRRQDVFSLGICNGCQLMTLIGFVGSAKSEVGADPDV 1205
Query: 101 -LRPNKIPRFICKWIYLKVNDTNTAFTQLYEEGEIIRMPIAHAEGNYYVDDPSRIR---- 155
L NK RF C+W +K+ + ++ ++ +AH EG + D I
Sbjct: 1206 ALLHNKSQRFECRWATVKIPSNRSIMLGSMKD-LVLGCWVAHGEGRFAFRDEKLISHLQS 1264
Query: 156 ---IVFQYSDENGNLTE--EANPNGSVMNIAGVSNEGGNVLGMMPHPERASDAF 204
+ QY D+ G TE NPNGS IAG+ + G L +MPHPER S +
Sbjct: 1265 EQLVTLQYVDDVGKPTELYPLNPNGSPQGIAGLCSSDGRHLALMPHPERCSSMY 1318
>gb|AAF52329.1| (AE003612) ade2 gene product [Drosophila melanogaster]
Length = 1354
Score = 95.6 bits (234), Expect = 5e-19
Identities = 72/234 (30%), Positives = 104/234 (43%), Gaps = 33/234 (14%)
Query: 3 RFAVIVFPGTNCDFETVEAIRKAGGEAERVWYKE------SIREYDGVVLPGGFSYADYL 56
R AV+ G N + E + + +A E V + S+ +Y G++ PGGFSYAD L
Sbjct: 1086 RVAVLREEGVNSEREMMACLLRANFEVHDVTMSDLLQGTASVSQYRGLIFPGGFSYADTL 1145
Query: 57 R-----AGAIAARQRIMEEVREFAEEGRPV-LGICNGFQVLTEAGLLPGA---------- 100
A I R++ + F LGICNG Q++T G + A
Sbjct: 1146 GSAKGWAANILHNPRLLPQFEAFKRRQDVFSLGICNGCQLMTLIGFVGSAKSEVGADPDV 1205
Query: 101 -LRPNKIPRFICKWIYLKVNDTNTAFTQLYEEGEIIRMPIAHAEGNYYVDDPSRIR---- 155
L NK RF C+W +K+ + ++ ++ +AH EG + D I
Sbjct: 1206 ALLHNKSQRFECRWATVKIPSNRSIMLGSMKD-LVLGCWVAHGEGRFAFRDEKLISHLQS 1264
Query: 156 ---IVFQYSDENGNLTE--EANPNGSVMNIAGVSNEGGNVLGMMPHPERASDAF 204
+ QY D+ G TE NPNGS IAG+ + G L +MPHPER S +
Sbjct: 1265 EQLVTLQYVDDVGKPTELYPLNPNGSPQGIAGLCSSDGRHLALMPHPERCSSMY 1318
>gb|AAF31730.1|AC020579_7 (AC020579) putative phosphoribosylformylglycinamidine synthase;
25509-29950 [Arabidopsis thaliana]
Length = 1387
Score = 89.3 bits (218), Expect = 3e-17
Identities = 74/234 (31%), Positives = 113/234 (47%), Gaps = 38/234 (16%)
Query: 1 MPRFAVIVFPGTNCDFETVEAIRKAGGEAERVWYKE------SIREYDGVVLPGGFSYAD 54
+P+ AVI G+N D E A AG E V + ++ ++ G+V GGFSYAD
Sbjct: 1119 IPKVAVIREEGSNGDREMSAAFYAAGFEPWDVTVSDLLAGDITLDQFRGIVFVGGFSYAD 1178
Query: 55 YLR-----AGAIAARQRIMEEVREFAEEGRP---VLGICNGFQVLTEAGLLPG------- 99
L A +I + ++ + +EF + RP LGICNG Q++ G +PG
Sbjct: 1179 VLDSAKGWAASIRFNEPVLSQFQEFYK--RPDTFSLGICNGCQLMALLGWVPGPQVGGSL 1236
Query: 100 -ALRP----NKIPRFICKWIYLKVNDTNTAFTQLYEEGEIIRMPIAHAEGNYYVDDPSRI 154
+P N+ RF C++ + + D+ + + E G + + AH EG Y D +
Sbjct: 1237 DTSQPRFVHNESGRFECRFTSVTIKDSPSIMLKGME-GSTLGVWAAHGEGRAYFPDEGVL 1295
Query: 155 RIVF-------QYSDENGNLTEEA--NPNGSVMNIAGVSNEGGNVLGMMPHPER 199
+ +Y D++GN+TE N NGS + IA + + G L MMPHPER
Sbjct: 1296 DHMLHSDLAPLRYCDDDGNVTEAYPFNLNGSPLGIAAICSPDGRHLAMMPHPER 1349
>pir||H64090 phosphoribosylformylglycinamidine synthase (EC 6.3.5.3) - Haemophilus
influenzae (strain Rd KW20) >gi|1573760|gb|AAC22411.1|
(U32759) phosphoribosylformylglycinamidine synthase
(purL) [Haemophilus influenzae Rd]
Length = 1320
Score = 87.0 bits (212), Expect = 2e-16
Identities = 75/251 (29%), Positives = 115/251 (44%), Gaps = 37/251 (14%)
Query: 2 PRFAVIVFPGTNCDFETVEAIRKAGGEAERVWYKE------SIREYDGVVLPGGFSYADY 55
P A++ G N +E A +AG A V + ++ E++ +V GGFSY D
Sbjct: 1066 PTIAILREQGVNSHYEMAAAFDRAGFNAIDVHMSDLMIGRRNLAEFNAMVACGGFSYGDV 1125
Query: 56 LRAG-----AIAARQRIMEEVREF-AEEGRPVLGICNGFQVLTE-AGLLPGALR-----P 103
L AG +I ++ E+ +F LG+CNG Q+++ A ++PG
Sbjct: 1126 LGAGGGWAKSILFNPKLHEQFSQFFINPNTLTLGVCNGCQMISNLAEIIPGTENWPHFVR 1185
Query: 104 NKIPRFICKWIYLKVNDTNTAFTQLYEEGEIIRMPIAHAEGNYYVDDPSRIR-------I 156
NK RF + +K+N+ ++ + G + + ++H EG + I
Sbjct: 1186 NKSERFEARVSLVKINEVDSVWFAGMA-GSHMPIAVSHGEGQVKFKSVEQFAGLKAQGII 1244
Query: 157 VFQYSDENGNLTE--EANPNGSVMNIAGVSNEGGNVLGMMPHPERASDAFLGS------- 207
QY D NG+ TE ANPNGS I ++N G V MMPHPER A S
Sbjct: 1245 AAQYIDNNGSPTELYPANPNGSSEGITAITNLDGRVAIMMPHPERVFRAVSNSWHPENWT 1304
Query: 208 EDG--LKVFRS 216
EDG +++FR+
Sbjct: 1305 EDGAWMRLFRN 1315
>sp|P43847|PURL_HAEIN PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE (FGAM SYNTHASE)
(FORMYLGLYCINAMIDE RIBOTIDE AMIDOTRANSFERASE) (FGARAT)
Length = 1297
Score = 87.0 bits (212), Expect = 2e-16
Identities = 75/251 (29%), Positives = 115/251 (44%), Gaps = 37/251 (14%)
Query: 2 PRFAVIVFPGTNCDFETVEAIRKAGGEAERVWYKE------SIREYDGVVLPGGFSYADY 55
P A++ G N +E A +AG A V + ++ E++ +V GGFSY D
Sbjct: 1043 PTIAILREQGVNSHYEMAAAFDRAGFNAIDVHMSDLMIGRRNLAEFNAMVACGGFSYGDV 1102
Query: 56 LRAG-----AIAARQRIMEEVREF-AEEGRPVLGICNGFQVLTE-AGLLPGALR-----P 103
L AG +I ++ E+ +F LG+CNG Q+++ A ++PG
Sbjct: 1103 LGAGGGWAKSILFNPKLHEQFSQFFINPNTLTLGVCNGCQMISNLAEIIPGTENWPHFVR 1162
Query: 104 NKIPRFICKWIYLKVNDTNTAFTQLYEEGEIIRMPIAHAEGNYYVDDPSRIR-------I 156
NK RF + +K+N+ ++ + G + + ++H EG + I
Sbjct: 1163 NKSERFEARVSLVKINEVDSVWFAGMA-GSHMPIAVSHGEGQVKFKSVEQFAGLKAQGII 1221
Query: 157 VFQYSDENGNLTE--EANPNGSVMNIAGVSNEGGNVLGMMPHPERASDAFLGS------- 207
QY D NG+ TE ANPNGS I ++N G V MMPHPER A S
Sbjct: 1222 AAQYIDNNGSPTELYPANPNGSSEGITAITNLDGRVAIMMPHPERVFRAVSNSWHPENWT 1281
Query: 208 EDG--LKVFRS 216
EDG +++FR+
Sbjct: 1282 EDGAWMRLFRN 1292
>sp|P15254|PURL_ECOLI PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE (FGAM SYNTHASE)
(FORMYLGLYCINAMIDE RIBOTIDE AMIDOTRANSFERASE) (FGARAT)
>gi|147423|gb|AAA24456.1| (M19501) formylglycineamide
ribonucleotide synthetase (EC 6.3.5.3) [Escherichia coli]
>gi|1033146|gb|AAA79819.1| (U36841)
phosphoribosylformylglycineamide synthetase [Escherichia
coli]
Length = 1295
Score = 86.6 bits (211), Expect = 2e-16
Identities = 76/251 (30%), Positives = 116/251 (45%), Gaps = 37/251 (14%)
Query: 2 PRFAVIVFPGTNCDFETVEAIRKAGGEAERVWYKE------SIREYDGVVLPGGFSYADY 55
P+ AV+ G N E A +AG +A V + + ++ +V GGFSY D
Sbjct: 1040 PKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLTGRTGLEDFHALVACGGFSYGDV 1099
Query: 56 LRAG-----AIAARQRIMEEVREFAEEGRPV-LGICNGFQVLTEAG-LLPGA-LRP---- 103
L AG +I R+ +E F + + LG+CNG Q+++ L+PG+ L P
Sbjct: 1100 LGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGVCNGCQMMSNLRELIPGSELWPRFVR 1159
Query: 104 NKIPRFICKWIYLKVNDTNTAFTQLYEEGEIIRMPIAHAEGNYYVDDPSRIR-------I 156
N RF ++ ++V + + Q G + + ++H EG V D + + +
Sbjct: 1160 NTSDRFEARFSLVEVTQSPSLLLQGMV-GSQMPIAVSHGEGRVEVRDAAHLAALESKGLV 1218
Query: 157 VFQYSDENGNLTEE--ANPNGSVMNIAGVSNEGGNVLGMMPHPERASDAFLGS------- 207
+Y D G +TE ANPNGS I V+ E G V MMPHPER S
Sbjct: 1219 ALRYVDNFGKVTETYPANPNGSPNGITAVTTESGRVTIMMPHPERVFRTVSNSWHPENWG 1278
Query: 208 EDG--LKVFRS 216
EDG +++FR+
Sbjct: 1279 EDGPWMRIFRN 1289
>pir||SYECPG phosphoribosylformylglycinamidine synthase (EC 6.3.5.3) [validated] -
Escherichia coli >gi|1788909|gb|AAC75610.1| (AE000342)
phosphoribosylformyl-glycineamide synthetase = FGAM
synthetase [Escherichia coli K12]
Length = 1295
Score = 86.6 bits (211), Expect = 2e-16
Identities = 76/251 (30%), Positives = 116/251 (45%), Gaps = 37/251 (14%)
Query: 2 PRFAVIVFPGTNCDFETVEAIRKAGGEAERVWYKE------SIREYDGVVLPGGFSYADY 55
P+ AV+ G N E A +AG +A V + + ++ +V GGFSY D
Sbjct: 1040 PKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLTGRTGLEDFHALVACGGFSYGDV 1099
Query: 56 LRAG-----AIAARQRIMEEVREFAEEGRPV-LGICNGFQVLTEAG-LLPGA-LRP---- 103
L AG +I R+ +E F + + LG+CNG Q+++ L+PG+ L P
Sbjct: 1100 LGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGVCNGCQMMSNLRELIPGSELWPRFVR 1159
Query: 104 NKIPRFICKWIYLKVNDTNTAFTQLYEEGEIIRMPIAHAEGNYYVDDPSRIR-------I 156
N RF ++ ++V + + Q G + + ++H EG V D + + +
Sbjct: 1160 NTSDRFEARFSLVEVTQSPSLLLQGMV-GSQMPIAVSHGEGRVEVRDAAHLAALESKGLV 1218
Query: 157 VFQYSDENGNLTEE--ANPNGSVMNIAGVSNEGGNVLGMMPHPERASDAFLGS------- 207
+Y D G +TE ANPNGS I V+ E G V MMPHPER S
Sbjct: 1219 ALRYVDNFGKVTETYPANPNGSPNGITAVTTESGRVTIMMPHPERVFRTVSNSWHPENWG 1278
Query: 208 EDG--LKVFRS 216
EDG +++FR+
Sbjct: 1279 EDGPWMRIFRN 1289
>gb|AAB08888.1| (U68728) phosphoribosylformylglycinamidine synthetase [Salmonella
typhimurium]
Length = 1295
Score = 84.7 bits (206), Expect = 9e-16
Identities = 70/225 (31%), Positives = 105/225 (46%), Gaps = 28/225 (12%)
Query: 2 PRFAVIVFPGTNCDFETVEAIRKAGGEAERVWYKE------SIREYDGVVLPGGFSYADY 55
P+ AV+ G N E A +AG +A V + + + +V GGFSY D
Sbjct: 1040 PKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLGGRIGLGNFHALVACGGFSYGDV 1099
Query: 56 LRAG-----AIAARQRIMEEVREFAEEGRPV-LGICNGFQVLTEAG-LLPGA-LRP---- 103
L AG +I R+ +E F + + LG+CNG Q+++ L+PG+ L P
Sbjct: 1100 LGAGEGWAKSILFNHRVRDEFETFFHRPQTLALGVCNGCQMMSNLRELIPGSELWPRFVR 1159
Query: 104 NKIPRFICKWIYLKVNDTNTAFTQLYEEGEIIRMPIAHAEGNYYVDDPSRIR-------I 156
N RF ++ ++V + + Q G + + ++H EG V D + + +
Sbjct: 1160 NHSDRFEARFSLVEVTQSPSLLLQGMV-GSQMPIAVSHGEGRVEVRDDAHLAALESKGLV 1218
Query: 157 VFQYSDENGNLTEE--ANPNGSVMNIAGVSNEGGNVLGMMPHPER 199
+Y D G +TE ANPNGS I V+ E G V MMPHPER
Sbjct: 1219 ALRYVDNFGKVTETYPANPNGSPNGITAVTTENGRVTIMMPHPER 1263
>dbj|BAA20816.1| (AB002359) KIAA0361 [Homo sapiens]
Length = 1371
Score = 84.3 bits (205), Expect = 1e-15
Identities = 75/242 (30%), Positives = 106/242 (42%), Gaps = 46/242 (19%)
Query: 2 PRFAVIVFPGTNCDFETVEAIRKAGGEAERVWYKE------SIREYDGVVLPGGFSYADY 55
PR A++ G+N D E +A AG E V ++ + + GV GGFSYAD
Sbjct: 1096 PRVAILREEGSNGDREMADAFHLAGFEVWDVTMQDLCSGAIGLDTFRGVAFVGGFSYADV 1155
Query: 56 LR-----AGAIAARQRIMEEVREFAEEGRP---VLGICNGFQVLTEAGLLPG-------- 99
L A A+ R E+R F + RP LG+CNG Q+L G + G
Sbjct: 1156 LGSAKGWAAAVTFHPRAGAELRRFRK--RPDTFSLGVCNGCQLLALLGWVGGDPNEDAAE 1213
Query: 100 ------------ALRPNKIPRFICKWIYLKVNDTNTAFTQLYEEGEIIRMPIAHAEGNYY 147
LR N R+ +W ++V A EG ++ + AH EG
Sbjct: 1214 MGPDSQPARPGLLLRHNLSGRYESRWASVRVGP-GPALMLRGMEGAVLPVWSAHGEGYVA 1272
Query: 148 VDDP-------SRIRIVFQYSDENGNLTEE--ANPNGSVMNIAGVSNEGGNVLGMMPHPE 198
P +R ++D++GN TE+ NPNGS +AG+ + G L +MPHPE
Sbjct: 1273 FSSPELQAQIEARGLAPLHWADDDGNPTEQYPLNPNGSPGGVAGICSCDGRHLAVMPHPE 1332
Query: 199 RA 200
RA
Sbjct: 1333 RA 1334
>pir||A82272 phosphoribosylformylglycinamidine synthase VC0869 [imported] - Vibrio
cholerae (group O1 strain N16961)
>gi|9655322|gb|AAF94031.1| (AE004171)
phosphoribosylformylglycinamidine synthase [Vibrio
cholerae]
Length = 1297
Score = 84.3 bits (205), Expect = 1e-15
Identities = 74/227 (32%), Positives = 107/227 (46%), Gaps = 32/227 (14%)
Query: 2 PRFAVIVFPGTNCDFETVEAIRKAGGEAERVWYKESIR------EYDGVVLPGGFSYADY 55
P+ A++ G N E A +AG +A V + + Y G+V GGFSY D
Sbjct: 1042 PKMAILREQGVNSHVEMAAAFDRAGFDAVDVHMSDILTGQTVLDAYQGLVACGGFSYGDV 1101
Query: 56 LRAG-----AIAARQRIMEEVREFAEEGRPV-LGICNGFQVLTEA-GLLPGA-LRP---- 103
L AG +I + E+ +F + LG+CNG Q+L+ L+PGA L P
Sbjct: 1102 LGAGEGWAKSILFNAQAREQFEQFFQRKDTFSLGVCNGCQMLSNLRDLIPGAELWPRFVR 1161
Query: 104 NKIPRFICKWIYLKVNDTNTAFTQLYEEGEIIRMPIA--HAEGNYYVDDPSRIRIVFQ-- 159
N+ RF ++ ++V + + F + E RMPIA H EG V D + + Q
Sbjct: 1162 NESDRFEARFSLVEVQKSPSLF---FSEMAGSRMPIAVSHGEGRVEVRDAQHLAAIEQSG 1218
Query: 160 -----YSDENGNLTEE--ANPNGSVMNIAGVSNEGGNVLGMMPHPER 199
+ D G T+ +NPNGS I G++ + G V MMPHPER
Sbjct: 1219 TVAIRFVDNFGQPTQAYPSNPNGSPNAITGLTTQDGRVTIMMPHPER 1265
>pir||B83175 phosphoribosylformylglycinamidine synthase PA3763 [imported] -
Pseudomonas aeruginosa (strain PAO1)
>gi|9949933|gb|AAG07150.1|AE004795_2 (AE004795)
phosphoribosylformylglycinamidine synthase [Pseudomonas
aeruginosa]
Length = 1298
Score = 83.1 bits (202), Expect = 3e-15
Identities = 75/251 (29%), Positives = 116/251 (45%), Gaps = 37/251 (14%)
Query: 2 PRFAVIVFPGTNCDFETVEAIRKAGGEAERVWYKE------SIREYDGVVLPGGFSYADY 55
P+ A++ G N E A +AG A V + + + G+V GGFSY D
Sbjct: 1043 PKVAILREQGVNGQVEMAAAFDRAGFAAIDVHMSDILAGRVDLDAFKGLVACGGFSYGDV 1102
Query: 56 LRAGAIAARQRIME-EVRE-----FAEEGRPVLGICNGFQVLTEAG-LLPGA-----LRP 103
L AG A+ + R+ FA + LG+CNG Q+++ L+PG
Sbjct: 1103 LGAGEGWAKSILFNARARDGFQAFFARKDSFALGVCNGCQMMSNLHELIPGTEFWPHFVR 1162
Query: 104 NKIPRFICKWIYLKVNDTNTAFTQLYEEGEIIRMPIAHAEGNYYVDDPSRIR-------I 156
N+ +F + ++V ++++ F Q G + + IAH EG+ + + +
Sbjct: 1163 NRSEQFEARVAMVQVQESSSIFLQGMA-GSRLPIAIAHGEGHAEFESEEALLEADLSGCV 1221
Query: 157 VFQYSDENGNLTEE--ANPNGSVMNIAGVSNEGGNVLGMMPHPERASDAFLGS------- 207
++ D +G +TE ANPNGS I G+S+ G V MMPHPER A S
Sbjct: 1222 SLRFVDNHGKVTEAYPANPNGSPRGITGLSSRDGRVTIMMPHPERVFRAVQNSWRPDDWQ 1281
Query: 208 EDG--LKVFRS 216
EDG L++FR+
Sbjct: 1282 EDGGWLRMFRN 1292
>pir||G81017 phosphoribosylformylglycinamidine synthase NMB1996 [imported] -
Neisseria meningitidis (group B strain MD58)
>gi|7227259|gb|AAF42323.1| (AE002549)
phosphoribosylformylglycinamidine synthase [Neisseria
meningitidis MC58]
Length = 1320
Score = 76.5 bits (185), Expect = 3e-13
Identities = 64/222 (28%), Positives = 101/222 (44%), Gaps = 24/222 (10%)
Query: 2 PRFAVIVFPGTNCDFETVEAIRKAGGEAERVWYKE------SIREYDGVVLPGGFSYADY 55
P+ A++ G N E A +AG +A V + + ++ + GGFSY D
Sbjct: 1067 PKIAILREQGVNGQIEMAAAFTRAGFDAYDVHMSDLMAGRIHLADFKMLAACGGFSYGDV 1126
Query: 56 LRAGAIAARQRIMEEVRE------FAEEGRPVLGICNGFQVLTE-AGLLPGALRPNKIPR 108
L AG A+ + FA+ LG+CNG Q+++ A ++PG K R
Sbjct: 1127 LGAGEGWAKSILFHPALRDQFAAFFADPDTLTLGVCNGCQMVSNLAEIIPGTAGWPKFKR 1186
Query: 109 FICKWIYLK---VNDTNTAFTQLYE-EGEIIRMPIAHAEGN-----YYVDDPSRIRIVFQ 159
+ + + V+ +A L E +G + + ++H EG + + + + I Q
Sbjct: 1187 NLSEQFEARLSMVHVPKSASLILNEMQGSSLPVVVSHGEGRADFALHGGNISADLGIALQ 1246
Query: 160 YSDENGNLTEE--ANPNGSVMNIAGVSNEGGNVLGMMPHPER 199
Y D +T+ NPNGS IAGV+N G + MMPHPER
Sbjct: 1247 YIDGQNQVTQTYPLNPNGSPQGIAGVTNADGRITIMMPHPER 1288
>pir||G81961 phosphoribosylformylglycinamidine synthase (EC 6.3.5.3) NMA0445
[imported] - Neisseria meningitidis (group A strain
Z2491) >gi|7379194|emb|CAB83743.1| (AL162753)
phophoribosylformylglycinamidine synthase [Neisseria
meningitidis Z2491]
Length = 1320
Score = 76.1 bits (184), Expect = 3e-13
Identities = 64/222 (28%), Positives = 100/222 (44%), Gaps = 24/222 (10%)
Query: 2 PRFAVIVFPGTNCDFETVEAIRKAGGEAERVWYKE------SIREYDGVVLPGGFSYADY 55
P+ A++ G N E A +AG +A V + + ++ + GGFSY D
Sbjct: 1067 PKIAILREQGVNGQIEMAAAFTRAGFDAYDVHMSDLMAGRVHLADFKMLAACGGFSYGDV 1126
Query: 56 LRAGAIAARQRIMEEVRE------FAEEGRPVLGICNGFQVLTE-AGLLPGALRPNKIPR 108
L AG A+ + F + LG+CNG Q+++ A ++PG K R
Sbjct: 1127 LGAGKGWAKSILFHPALRDQFAAFFTDPNTLTLGVCNGCQMVSNLAEIIPGTAGWPKFKR 1186
Query: 109 FICKWIYLK---VNDTNTAFTQLYE-EGEIIRMPIAHAEGN-----YYVDDPSRIRIVFQ 159
+ + + V+ +A L E +G + + ++H EG + + + + I Q
Sbjct: 1187 NLSEQFEARLSMVHVPKSASLILNEMQGSSLPVVVSHGEGRADFALHGGNISADLGIALQ 1246
Query: 160 YSDENGNLTEE--ANPNGSVMNIAGVSNEGGNVLGMMPHPER 199
Y D +T+ NPNGS IAGV+N G V MMPHPER
Sbjct: 1247 YVDGQNQITQTYPLNPNGSPQGIAGVTNADGRVTIMMPHPER 1288
>pir||D82685 phosphoribosylformylglycinamidine synthetase XF1423 [imported] -
Xylella fastidiosa (strain 9a5c)
>gi|9106435|gb|AAF84232.1|AE003972_17 (AE003972)
phosphoribosylformylglycinamidine synthetase [Xylella
fastidiosa]
Length = 1322
Score = 71.8 bits (173), Expect = 7e-12
Identities = 61/221 (27%), Positives = 96/221 (42%), Gaps = 24/221 (10%)
Query: 2 PRFAVIVFPGTNCDFETVEAIRKAGGEAERVWYKESIR------EYDGVVLPGGFSYADY 55
P A++ G N E +AG + + I E+ G+ GGFSY D
Sbjct: 1071 PTVAILREQGINGHIEMALCFERAGFHCVDIHMNDLITGRVHLDEFVGLAACGGFSYGDV 1130
Query: 56 LRAG-----AIAARQRIMEEVREF-AEEGRPVLGICNGFQVLTEA-GLLPGALR-----P 103
L AG +I R + ++ F R LG+CNG Q+L++ ++PGA
Sbjct: 1131 LGAGRGWATSILERTALRDQFAAFFTRTDRFALGVCNGCQMLSQLKSMIPGAEHWPRFVR 1190
Query: 104 NKIPRFICKWIYLKVNDTNTAFTQLYEEGEIIRMPIAHAEGNYYVDDPS---RIRIVFQY 160
N+ +F + L+V + + F G + + +AH EG D P+ + +Y
Sbjct: 1191 NRSEQFEARTALLEVIQSPSIFLSGMA-GSRLPVAVAHGEGYAMFDTPADQAAAHVALRY 1249
Query: 161 SDENGNLTEE--ANPNGSVMNIAGVSNEGGNVLGMMPHPER 199
+ +G NPNGS I G++ G + +MPHPER
Sbjct: 1250 INGHGQAATHYPLNPNGSPNGITGLTTTDGRITILMPHPER 1290
>gi|6321498 5'-phosphoribosylformyl glycinamidine synthetase; Ade6p
[Saccharomyces cerevisiae]
>gi|1709924|sp|P38972|PUR4_YEAST
PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE (FGAM
SYNTHASE) (FORMYLGLYCINAMIDE RIBOTIDE AMIDOTRANSFERASE)
(FGARAT) >gi|2118366|pir||S64356
phosphoribosylformylglycinamidine synthase (EC 6.3.5.3) -
yeast (Saccharomyces cerevisiae)
>gi|1323079|emb|CAA97063.1| (Z72846) ORF YGR061c
[Saccharomyces cerevisiae]
Length = 1358
Score = 70.2 bits (169), Expect = 2e-11
Identities = 62/232 (26%), Positives = 95/232 (40%), Gaps = 34/232 (14%)
Query: 2 PRFAVIVFPGTNCDFETVEAIRKAGGEAERVWYKESIR------EYDGVVLPGGFSYADY 55
P+ A++ G N E ++AG + V + + ++ G+ GGFSY D
Sbjct: 1091 PKVAILREQGVNGQMEMAWCFQQAGFNSVDVTMTDLLEGRFHLDDFIGLAACGGFSYGDV 1150
Query: 56 LRAGA-----IAARQRIMEEVREFAEEGRPVL--GICNGFQVLTEA-GLLPGALRPNKIP 107
L AGA + + + + +F E + G CNG Q L+ ++PG
Sbjct: 1151 LGAGAGWAKSVLYHEGVRSQFSKFFNERQDTFAFGACNGCQFLSRLKDIIPGCENWPSFE 1210
Query: 108 RFICKWIYLKV----------NDTNTAFTQLYEEGEIIRMPIAHAEGNYYVDDPSRIRIV 157
R + + +V N + + G + + +AH EG +
Sbjct: 1211 RNVSEQYEARVCMVQISQEKDNSSEESVFLNGMAGSKLPIAVAHGEGKATFSKSAEQLEK 1270
Query: 158 FQ--------YSDENGNLTEEA--NPNGSVMNIAGVSNEGGNVLGMMPHPER 199
F+ Y D GN+TE NPNGS IAG+ + G VL MMPHPER
Sbjct: 1271 FEKDGLCCIRYVDNYGNVTERFPFNPNGSTNGIAGIKSPNGRVLAMMPHPER 1322
>pir||T11661 phosphoribosylformylglycinamidine synthase (EC 6.3.5.3) - fission
yeast (Schizosaccharomyces pombe)
>gi|2330857|emb|CAB11094.1| (Z98533)
phosphoribosylformylglycinamidine synthase
[Schizosaccharomyces pombe]
Length = 1323
Score = 70.2 bits (169), Expect = 2e-11
Identities = 64/228 (28%), Positives = 102/228 (44%), Gaps = 30/228 (13%)
Query: 2 PRFAVIVFPGTNCDFETVEAIRKAGGEAERVWYKESIR------EYDGVVLPGGFSYADY 55
P+ A++ G N E A +G A V + + ++ G+ GGFSY D
Sbjct: 1060 PKVAILREQGVNGYLEMAYAFYASGFTAVDVHMTDILSGRVHLDDFVGIAACGGFSYGDV 1119
Query: 56 LRAG-----AIAARQRIMEEVREFAEEGRPV--LGICNGFQVLTEA-GLLPGA-----LR 102
L +G +I + E F E + LGICNG Q+ + L+PGA
Sbjct: 1120 LGSGNGWATSILLHEDARNEFYRFFNERKDTFGLGICNGCQLFSRLKSLIPGAKSWPMFT 1179
Query: 103 PNKIPRFICKWIYLKVNDTNTAFTQLYEE--GEIIRMPIAHAEGNYYVDDPSR------- 153
N+ ++ + + LK+++T+ + + E G + + +AH EG D S
Sbjct: 1180 FNESAQYEGRAVMLKIDETSGSKSIFTESMAGSSLPVVVAHGEGRAVFDSESDYEQFKKE 1239
Query: 154 -IRIVFQYSDENGNLTEEA-NPNGSVMNIAGVSNEGGNVLGMMPHPER 199
+ +++ ++ N + NPNGS IAGV + G L MMPHPER
Sbjct: 1240 GLDLIYYVNNYNERTSRYPFNPNGSRDAIAGVRSPCGRFLAMMPHPER 1287
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.319 0.139 0.415
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 90684465
Number of Sequences: 2977
Number of extensions: 4044211
Number of successful extensions: 9425
Number of sequences better than 1.0e-10: 37
Number of HSP's better than 0.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 9322
Number of HSP's gapped (non-prelim): 37
length of query: 223
length of database: 189,106,746
effective HSP length: 53
effective length of query: 170
effective length of database: 157,386,935
effective search space: 26755778950
effective search space used: 26755778950
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 163 (67.9 bits)