BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB1206 (pcm) DE:L-isoaspartyl protein carboxyl
methyltransferase (pcm)
(219 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||E75025 l-isoaspartyl protein carboxyl methyltransferase (pc... 446 e-124
pir||A71202 probable L-isoaspartyl protein carboxyl methyltransf... 387 e-107
sp|O59534|PIMT_PYRHO PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE ... 387 e-107
gi|11499903 L-isoaspartyl protein carboxyl methyltransferase (pc... 210 9e-54
sp|Q57636|PIMT_METJA PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE ... 208 4e-53
gi|11497657 L-isoaspartyl protein carboxyl methyltransferase (pc... 202 3e-51
sp|O26915|PIMT_METTH PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE ... 198 6e-50
sp|Q9YDA1|PIMT_AERPE PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE ... 196 2e-49
pir||T06709 protein-L-isoaspartate(D-aspartate) O-methyltransfer... 148 4e-35
sp|Q42539|PIMT_ARATH PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE ... 148 7e-35
sp|Q43209|PIMT_WHEAT PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE ... 147 1e-34
sp|P24206|PIMT_ECOLI PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE ... 135 4e-31
pir||G82311 protein-L-isoaspartate O-methyltransferase VC0532 [i... 132 2e-30
pir||F83193 L-isoaspartate protein carboxylmethyltransferase typ... 131 1e-29
sp|P23506|PIMT_MOUSE PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHY... 119 3e-26
sp|P15246|PIMT_BOVIN PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHY... 117 1e-25
gi|6981338 protein-L-isoaspartate (D-aspartate) O-methyltransfer... 117 1e-25
gi|6679217 protein-L-isoaspartate (D-aspartate) O-methyltransfer... 117 1e-25
pir||A43292 protein-L-isoaspartate(D-aspartate) O-methyltransfer... 117 1e-25
sp|Q56308|PIMT_THEMA PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE ... 117 1e-25
gi|4885539 protein-L-isoaspartate (D-aspartate) O-methyltransfer... 117 1e-25
pir||JH0624 protein-L-isoaspartate(D-aspartate) O-methyltransfer... 117 1e-25
gi|11417533 protein-L-isoaspartate (D-aspartate) O-methyltransfe... 117 1e-25
prf||2110330A isoAsp protein carboxyl methyltransferase [Homo sa... 116 2e-25
sp|P22061|PIMT_HUMAN PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHY... 116 2e-25
pir||A34489 protein-L-isoaspartate(D-aspartate) O-methyltransfer... 116 3e-25
sp|Q92047|PIMT_BRARE PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHY... 116 3e-25
gb|AAF52012.1| (AE003602) Pcmt gene product [Drosophila melanoga... 115 6e-25
sp|Q27869|PIMT_DROME PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHY... 114 8e-25
pir||C82754 L-isoaspartate O-methyltransferase XF0857 [imported]... 113 1e-24
emb|CAB92590.1| (AL356812) putative O-methyltransferase. [Strep... 112 3e-24
pir||T50917 hypothetical protein pcm [imported] - Rubrivivax gel... 112 3e-24
pir||I56505 protein-L-isoaspartate(D-aspartate) O-methyltransfer... 111 9e-24
sp|P56133|PIMT_HELPY PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE ... 107 1e-22
sp|Q9ZKC2|PIMT_HELPJ PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE ... 106 2e-22
gb|AAK42721.1| L-isoaspartyl protein carboxyl methyltransferase ... 102 3e-21
emb|CAB71208.1| (AL138538) putative O-methyltransferase [Strepto... 101 1e-20
sp|O08249|PIMT_RHIME PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE ... 100 1e-20
gb|AAB88075.1| (U81296) L-isoaspartyl protein carboxyl methyltra... 100 2e-20
pir||T39119 protein-L-isoaspartate(D-aspartate) O-methyltransfer... 98 7e-20
pir||D81440 protein-L-isoaspartate(D-aspartate) O-methyltransfer... 96 3e-19
dbj|BAB09395.1| (AB024031) contains similarity to L-isoaspartyl ... 95 6e-19
sp|Q27873|PIMT_CAEEL PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE ... 94 1e-18
pir||C81031 protein-L-isoaspartate O-methyltransferase NMB1885 [... 89 3e-17
pir||A81976 probable protein-L-isoaspartate(D-aspartate) O-methy... 89 3e-17
gb|AAG18721.1| (AE004977) L-isoaspartyl protein carboxyl methylt... 86 3e-16
gb|AAF70310.1|AF260132_1 (AF260132) putative protein-L-isoaspart... 82 6e-15
gb|AAA90933.1| (M93009) L-isoaspartyl/D-aspartyl protein carboxy... 79 4e-14
gb|AAF80359.1|AF157831_1 (AF157831) L-isoaspartyl protein carbox... 78 6e-14
sp|P45683|PIMT_PSEAE PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE ... 72 6e-12
pir||H82539 protein-L-isoaspartate O-methyltransferase XF2585 [i... 69 4e-11
>pir||E75025 l-isoaspartyl protein carboxyl methyltransferase (pcm) PAB1206 -
Pyrococcus abyssi (strain Orsay)
>gi|5459157|emb|CAB50643.1| (AJ248288) L-isoaspartyl
protein carboxyl methyltransferase (pcm) [Pyrococcus
abyssi]
Length = 219
Score = 446 bits (1135), Expect = e-124
Identities = 219/219 (100%), Positives = 219/219 (100%)
Query: 1 MVSMDLYERWKRTVEMLEREGIIRSLEVKEAFLKYPRYMFVEDRYKSYAHIDEPLPIPAG 60
MVSMDLYERWKRTVEMLEREGIIRSLEVKEAFLKYPRYMFVEDRYKSYAHIDEPLPIPAG
Sbjct: 1 MVSMDLYERWKRTVEMLEREGIIRSLEVKEAFLKYPRYMFVEDRYKSYAHIDEPLPIPAG 60
Query: 61 QTVSAPHMVAIMLEIAKLKEGMNVLEVGTGSGWNAALISYIVKTDVYSIERIPELVEFAK 120
QTVSAPHMVAIMLEIAKLKEGMNVLEVGTGSGWNAALISYIVKTDVYSIERIPELVEFAK
Sbjct: 61 QTVSAPHMVAIMLEIAKLKEGMNVLEVGTGSGWNAALISYIVKTDVYSIERIPELVEFAK 120
Query: 121 RNLERAGVKNVHVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPVGS 180
RNLERAGVKNVHVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPVGS
Sbjct: 121 RNLERAGVKNVHVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPVGS 180
Query: 181 YHLWQELLEVVKKKSGEIKVRNHGGVAFVPLIGEYGWRE 219
YHLWQELLEVVKKKSGEIKVRNHGGVAFVPLIGEYGWRE
Sbjct: 181 YHLWQELLEVVKKKSGEIKVRNHGGVAFVPLIGEYGWRE 219
>pir||A71202 probable L-isoaspartyl protein carboxyl methyltransferase -
Pyrococcus horikoshii >gi|3258325|dbj|BAA31008.1|
(AP000007) 272aa long hypothetical L-isoaspartyl protein
carboxyl methyltransferase [Pyrococcus horikoshii]
Length = 272
Score = 387 bits (984), Expect = e-107
Identities = 183/219 (83%), Positives = 204/219 (92%)
Query: 1 MVSMDLYERWKRTVEMLEREGIIRSLEVKEAFLKYPRYMFVEDRYKSYAHIDEPLPIPAG 60
M +LYE+WKRTVEML+ EGII+S +V+ AFLK PRY+FVEDRYK YAH+DEPLPIPAG
Sbjct: 54 MDEKELYEKWKRTVEMLKAEGIIKSEKVERAFLKCPRYLFVEDRYKKYAHVDEPLPIPAG 113
Query: 61 QTVSAPHMVAIMLEIAKLKEGMNVLEVGTGSGWNAALISYIVKTDVYSIERIPELVEFAK 120
QT+SAPHMVAIMLEIA LK GMNVLEVGTGSGWNAALI+ IVK DVYSIERIPELVEFAK
Sbjct: 114 QTISAPHMVAIMLEIADLKPGMNVLEVGTGSGWNAALIAEIVKGDVYSIERIPELVEFAK 173
Query: 121 RNLERAGVKNVHVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPVGS 180
RNLERAGVKNVHVILGDGSKGFPPK+PYD IIVTAGAP++P+PLVEQLKPGG+LIIPVGS
Sbjct: 174 RNLERAGVKNVHVILGDGSKGFPPKSPYDAIIVTAGAPEIPKPLVEQLKPGGKLIIPVGS 233
Query: 181 YHLWQELLEVVKKKSGEIKVRNHGGVAFVPLIGEYGWRE 219
YHLWQELLEV+K++ G IK++NHGGVAFVPLIGE+GWRE
Sbjct: 234 YHLWQELLEVIKREDGSIKIKNHGGVAFVPLIGEHGWRE 272
>sp|O59534|PIMT_PYRHO PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE (PROTEIN-BETA-ASPARTATE
METHYLTRANSFERASE) (PIMT) (PROTEIN L-ISOASPARTYL
METHYLTRANSFERASE) (L-ISOASPARTYL PROTEIN CARBOXYL
METHYLTRANSFERASE)
Length = 220
Score = 387 bits (984), Expect = e-107
Identities = 183/219 (83%), Positives = 204/219 (92%)
Query: 1 MVSMDLYERWKRTVEMLEREGIIRSLEVKEAFLKYPRYMFVEDRYKSYAHIDEPLPIPAG 60
M +LYE+WKRTVEML+ EGII+S +V+ AFLK PRY+FVEDRYK YAH+DEPLPIPAG
Sbjct: 2 MDEKELYEKWKRTVEMLKAEGIIKSEKVERAFLKCPRYLFVEDRYKKYAHVDEPLPIPAG 61
Query: 61 QTVSAPHMVAIMLEIAKLKEGMNVLEVGTGSGWNAALISYIVKTDVYSIERIPELVEFAK 120
QT+SAPHMVAIMLEIA LK GMNVLEVGTGSGWNAALI+ IVK DVYSIERIPELVEFAK
Sbjct: 62 QTISAPHMVAIMLEIADLKPGMNVLEVGTGSGWNAALIAEIVKGDVYSIERIPELVEFAK 121
Query: 121 RNLERAGVKNVHVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPVGS 180
RNLERAGVKNVHVILGDGSKGFPPK+PYD IIVTAGAP++P+PLVEQLKPGG+LIIPVGS
Sbjct: 122 RNLERAGVKNVHVILGDGSKGFPPKSPYDAIIVTAGAPEIPKPLVEQLKPGGKLIIPVGS 181
Query: 181 YHLWQELLEVVKKKSGEIKVRNHGGVAFVPLIGEYGWRE 219
YHLWQELLEV+K++ G IK++NHGGVAFVPLIGE+GWRE
Sbjct: 182 YHLWQELLEVIKREDGSIKIKNHGGVAFVPLIGEHGWRE 220
>gi|11499903 L-isoaspartyl protein carboxyl methyltransferase (pcm-2)
[Archaeoglobus fulgidus]
>gi|7387999|sp|O27962|PIM2_ARCFU PROTEIN-L-ISOASPARTATE
O-METHYLTRANSFERASE 2 (PROTEIN-BETA-ASPARTATE
METHYLTRANSFERASE 2) (PIMT 2) (PROTEIN L-ISOASPARTYL
METHYLTRANSFERASE 2) (L-ISOASPARTYL PROTEIN CARBOXYL
METHYLTRANSFERASE 2) >gi|7451062|pir||B69540
L-isoaspartyl protein carboxyl methyltransferase (pcm-2)
homolog - Archaeoglobus fulgidus
>gi|2648197|gb|AAB88934.1| (AE000944) L-isoaspartyl
protein carboxyl methyltransferase (pcm-2)
[Archaeoglobus fulgidus]
Length = 219
Score = 210 bits (530), Expect = 9e-54
Identities = 115/217 (52%), Positives = 150/217 (68%), Gaps = 5/217 (2%)
Query: 4 MDLYERWKRTVEMLEREGIIRSLEVKEAFLKYPRYMFVEDRYKSYAHIDEPLPIPAGQTV 63
MD E+ +R E L +E + S +V EA K PR++FV + YK+ A++D PLPI GQT+
Sbjct: 1 MDYDEKRERLAERLRQE-LNLSRKVYEAIRKVPRHLFVPESYKNEAYVDTPLPIGYGQTI 59
Query: 64 SAPHMVAIMLEIAKLKEGMNVLEVGTGSGWNAALISYIVKTD--VYSIERIPELVEFAKR 121
SAPHMVAIM E+ L+EG VLEVGTG G++AA+ + IV V SIE IPEL E A+
Sbjct: 60 SAPHMVAIMCELLDLREGDKVLEVGTGCGYHAAVTAEIVGKSGKVISIEYIPELAERARA 119
Query: 122 NLERAGVKNVHVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPVGSY 181
L+ G NV VI+GDGSKG+ +APYD I VTA AP +P+PL+EQLKP GR++IPVG
Sbjct: 120 ILKALGYDNVEVIVGDGSKGYEKEAPYDKIYVTAAAPDIPKPLIEQLKPRGRMVIPVGDS 179
Query: 182 HLWQELLEVVKKKSGEIKVRNHGGVAFVPLIGEYGWR 218
W L+ V K +SG ++ +N G V FVPL GEYG++
Sbjct: 180 VQW--LIIVEKDESGNVRKKNWGSVRFVPLRGEYGFK 214
>sp|Q57636|PIMT_METJA PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE (PROTEIN-BETA-ASPARTATE
METHYLTRANSFERASE) (PIMT) (PROTEIN L-ISOASPARTYL
METHYLTRANSFERASE) (L-ISOASPARTYL PROTEIN CARBOXYL
METHYLTRANSFERASE) >gi|2129092|pir||E64321 L-isoaspartyl
protein carboxyl methyltransferase - Methanococcus
jannaschii >gi|1590925|gb|AAB98157.1| (U67474)
L-isoaspartyl protein carboxyl methyltransferase
[Methanococcus jannaschii]
Length = 215
Score = 208 bits (524), Expect = 4e-53
Identities = 111/217 (51%), Positives = 148/217 (68%), Gaps = 5/217 (2%)
Query: 4 MDLYERWKRTVEMLEREGIIRSLEVKEAFLKYPRYMFVEDRYKSYAHIDEPLPIPAGQTV 63
MDL E+ K +E L REG I+S V +A LK PR F+ + K YA++D PL I GQT+
Sbjct: 1 MDLEEQKKAVIEKLIREGYIKSKRVIDALLKVPREEFLPEHLKEYAYVDTPLEIGYGQTI 60
Query: 64 SAPHMVAIMLEIAKLKEGMNVLEVGTGSGWNAALISYIVKTD--VYSIERIPELVEFAKR 121
SA HMV +M E+ LK GM VLE+GTG G++AA+ + IV D V SIERIPEL E A+R
Sbjct: 61 SAIHMVGMMCELLDLKPGMKVLEIGTGCGYHAAVTAEIVGEDGLVVSIERIPELAEKAER 120
Query: 122 NLERAGVKNVHVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPVGSY 181
L + G NV VI+GDG+ G+ P APYD I TA PK+PEPL+ QLK GG+L++PVG Y
Sbjct: 121 TLRKLGYDNVIVIVGDGTLGYEPLAPYDRIYTTAAGPKIPEPLIRQLKDGGKLLMPVGRY 180
Query: 182 HLWQELLEVVKKKSGEIKVRNHGGVAFVPLIGEYGWR 218
+ L + +K+ EI +++ G VAFVPL+G+ G++
Sbjct: 181 ---LQRLVLAEKRGDEIIIKDCGPVAFVPLVGKEGFQ 214
>gi|11497657 L-isoaspartyl protein carboxyl methyltransferase (pcm-1)
[Archaeoglobus fulgidus]
>gi|7388000|sp|O30199|PIM1_ARCFU PROTEIN-L-ISOASPARTATE
O-METHYLTRANSFERASE 1 (PROTEIN-BETA-ASPARTATE
METHYLTRANSFERASE 1) (PIMT 1) (PROTEIN L-ISOASPARTYL
METHYLTRANSFERASE 1) (L-ISOASPARTYL PROTEIN CARBOXYL
METHYLTRANSFERASE 1) >gi|7451061|pir||D69254
L-isoaspartyl protein carboxyl methyltransferase (pcm-1)
homolog - Archaeoglobus fulgidus
>gi|2650620|gb|AAB91197.1| (AE001104) L-isoaspartyl
protein carboxyl methyltransferase (pcm-1)
[Archaeoglobus fulgidus]
Length = 216
Score = 202 bits (508), Expect = 3e-51
Identities = 110/217 (50%), Positives = 151/217 (68%), Gaps = 7/217 (3%)
Query: 4 MDLYERWKRTVEMLEREGIIRSLEVKEAFLKYPRYMFVEDRYKSYAHIDEPLPIPAGQTV 63
MD E+ + E L R+ + S +V A K PR++FV +RY++ A++D PLPI GQT+
Sbjct: 1 MDFDEKRRILAERL-RDELNLSEKVYNAIKKVPRHLFVPERYRTMAYVDTPLPIGYGQTI 59
Query: 64 SAPHMVAIMLEIAKLKEGMNVLEVGTGSGWNAALISYIV--KTDVYSIERIPELVEFAKR 121
SAPHMVAIM E+ L+EG VLE+GTG G++AA+ + IV + V S+ERIPEL E AKR
Sbjct: 60 SAPHMVAIMCELLDLREGERVLEIGTGCGYHAAVTAEIVGKRGLVVSVERIPELAEIAKR 119
Query: 122 NLERAGVKNVHVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPVGSY 181
NL G +NV VI+GDGS G+ P APYD I VTA AP +P+PL+EQLK GG+++IP+G
Sbjct: 120 NLSALGYENVVVIVGDGSLGYEPMAPYDKIYVTASAPDIPKPLLEQLKIGGKMVIPIGE- 178
Query: 182 HLWQELLEVVKKKSGEIKVRNHGGVAFVPLIGEYGWR 218
+ L VV++ +G ++ + G V FVPL G+YG+R
Sbjct: 179 --TTQFLYVVERDNG-VRKWSWGAVRFVPLYGKYGFR 212
>sp|O26915|PIMT_METTH PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE (PROTEIN-BETA-ASPARTATE
METHYLTRANSFERASE) (PIMT) (PROTEIN L-ISOASPARTYL
METHYLTRANSFERASE) (L-ISOASPARTYL PROTEIN CARBOXYL
METHYLTRANSFERASE) >gi|7451060|pir||C69210 L-isoaspartyl
protein carboxyl methyltransferase - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2621917|gb|AAB85325.1| (AE000860) L-isoaspartyl
protein carboxyl methyltransferase [Methanobacterium
thermoautotrophicum]
Length = 217
Score = 198 bits (497), Expect = 6e-50
Identities = 102/210 (48%), Positives = 145/210 (68%), Gaps = 2/210 (0%)
Query: 11 KRTVEMLEREGIIRSLEVKEAFLKYPRYMFVEDRYKSYAHIDEPLPIPAGQTVSAPHMVA 70
+R V+ L G I+S V+ A + PR FV + A++D PLPI GQT+SAPHMVA
Sbjct: 6 RRMVQDLMERGYIKSEAVRRAMERVPREEFVPEDEMHRAYMDMPLPIGEGQTISAPHMVA 65
Query: 71 IMLEIAKLKEGMNVLEVGTGSGWNAALISYIVKTD--VYSIERIPELVEFAKRNLERAGV 128
++ EI L+ GM VLE+GTG G+NAA+I+ I+ + +Y++ERI L E A++ L G
Sbjct: 66 MIAEILDLEPGMKVLEIGTGCGYNAAVIAEIIGPEGHLYTVERIGILYERARKKLRSLGY 125
Query: 129 KNVHVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPVGSYHLWQELL 188
N+ VI GDGS+GF +APY I VTA AP +P+PL++QL+ GG+L+IPVGS +QEL+
Sbjct: 126 DNITVIHGDGSQGFADEAPYSRIYVTAAAPYIPDPLMKQLEIGGKLLIPVGSDKFYQELV 185
Query: 189 EVVKKKSGEIKVRNHGGVAFVPLIGEYGWR 218
+ + + + + RN GGVAFVPLIG++GW+
Sbjct: 186 LIERTSADDYRSRNLGGVAFVPLIGKHGWK 215
>sp|Q9YDA1|PIMT_AERPE PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE (PROTEIN-BETA-ASPARTATE
METHYLTRANSFERASE) (PIMT) (PROTEIN L-ISOASPARTYL
METHYLTRANSFERASE) (L-ISOASPARTYL PROTEIN CARBOXYL
METHYLTRANSFERASE) >gi|7516186|pir||D72699 hypothetical
protein APE1011 - Aeropyrum pernix (strain K1)
>gi|5104681|dbj|BAA79996.1| (AP000060) 256aa long
hypothetical protein-L-isoaspartate O-methyltransferase
[Aeropyrum pernix]
Length = 256
Score = 196 bits (492), Expect = 2e-49
Identities = 104/211 (49%), Positives = 140/211 (66%), Gaps = 4/211 (1%)
Query: 12 RTVEMLEREGIIRSLEVKEAFLKYPRYMFVEDRYKSYAHIDEPLPIPAGQTVSAPHMVAI 71
R VE L R G++ S V EA + PR++FV Y+ A+ D PLPI GQT+SAP +V
Sbjct: 36 RMVEQLRRSGLVTSRRVLEAMARVPRHLFVPPEYRGMAYEDRPLPIGHGQTISAPGVVGR 95
Query: 72 MLEIAKLKEGMNVLEVGTGSGWNAALISYIVKTD--VYSIERIPELVEFAKRNLERAGVK 129
ML++ + G VL+VG GSG+ +AL++ +V VY++ERIPEL E+A+ NLE+ G +
Sbjct: 96 MLQLLDPQPGEKVLDVGAGSGYQSALLAELVTPGGRVYAVERIPELAEYARENLEKTGYR 155
Query: 130 N-VHVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPVGSYHLWQELL 188
V V++GDGSKG P APY I V A APK P+PLVEQL PGGR++IP+G+ L Q L
Sbjct: 156 GVVEVVVGDGSKGLPQHAPYHRIKVAAAAPKPPKPLVEQLAPGGRMVIPIGTPDL-QILT 214
Query: 189 EVVKKKSGEIKVRNHGGVAFVPLIGEYGWRE 219
+ K G ++ R V FVPLIGE+G+RE
Sbjct: 215 IIEKTPDGRVRERRDIEVLFVPLIGEHGYRE 245
>pir||T06709 protein-L-isoaspartate(D-aspartate) O-methyltransferase (EC
2.1.1.77) [validated] - Arabidopsis thaliana
>gi|4678355|emb|CAB41165.1| (AL049659)
protein-L-isoaspartate(D-aspartate) O-methyltransferase
[Arabidopsis thaliana]
Length = 230
Score = 148 bits (371), Expect = 4e-35
Identities = 87/211 (41%), Positives = 131/211 (61%), Gaps = 14/211 (6%)
Query: 11 KRTVEMLEREGIIRSLEVKEAFLKYPRYMFVEDRYKSYAHIDEPLPIPAGQTVSAPHMVA 70
K VE L+ GI+ S EV +A R +FV DR S A++D P+ I T+SAPHM A
Sbjct: 14 KAMVENLQNHGIVTSDEVAKAMEAVDRGVFVTDR--SSAYVDSPMSIGYNVTISAPHMHA 71
Query: 71 IMLEIAK--LKEGMNVLEVGTGSGWNAALISYIVKTD--VYSIERIPELVEFAKRNLERA 126
+ L++ + LK GM VL+VG+G+G+ A + +V T+ +E IPELV + +N+E +
Sbjct: 72 MCLQLLEKHLKPGMRVLDVGSGTGYLTACFAVMVGTEGRAIGVEHIPELVASSVKNIEAS 131
Query: 127 GV------KNVHVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPVGS 180
+++ V +GDG +G+ APYD I V A AP++PE L++QLKPGGRL+IPVG
Sbjct: 132 AASPFLKERSLAVHVGDGRQGWAEFAPYDAIHVGAAAPEIPEALIDQLKPGGRLVIPVG- 190
Query: 181 YHLWQELLEVVKKKSGEIKVRNHGGVAFVPL 211
+++Q+L V K G + +++ V +VPL
Sbjct: 191 -NIFQDLQVVDKNSDGSVSIKDETSVRYVPL 220
>sp|Q42539|PIMT_ARATH PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE (PROTEIN-BETA-ASPARTATE
METHYLTRANSFERASE) (PIMT) (PROTEIN L-ISOASPARTYL
METHYLTRANSFERASE) (L-ISOASPARTYL PROTEIN CARBOXYL
METHYLTRANSFERASE) >gi|2129700|pir||S66344
protein-L-isoaspartate(D-aspartate) O-methyltransferase
(EC 2.1.1.77) - Arabidopsis thaliana
>gi|1322021|gb|AAC49279.1| (U31288) L-isoaspartyl
methyltransferase [Arabidopsis thaliana]
Length = 230
Score = 148 bits (369), Expect = 7e-35
Identities = 87/211 (41%), Positives = 130/211 (61%), Gaps = 14/211 (6%)
Query: 11 KRTVEMLEREGIIRSLEVKEAFLKYPRYMFVEDRYKSYAHIDEPLPIPAGQTVSAPHMVA 70
K VE L+ GI+ S EV +A R +FV DR S A++D P+ I T+SAPHM A
Sbjct: 14 KAMVENLQNHGIVTSDEVAKAMEAVDRGVFVTDR--SSAYVDSPMSIGYNVTISAPHMHA 71
Query: 71 IMLEIAK--LKEGMNVLEVGTGSGWNAALISYIVKTD--VYSIERIPELVEFAKRNLERA 126
+ L++ + LK GM VL+VG+G+G+ A + +V T+ +E IPELV + +N+E +
Sbjct: 72 MCLQLLEKHLKPGMRVLDVGSGTGYLTACFAVMVGTEGRAIGVEHIPELVASSVKNIEAS 131
Query: 127 GVK------NVHVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPVGS 180
++ V +GDG +G+ APYD I V A AP++PE L++QLKPGGRL+IPVG
Sbjct: 132 AASPFLKEGSLAVHVGDGRQGWAEFAPYDAIHVGAAAPEIPEALIDQLKPGGRLVIPVG- 190
Query: 181 YHLWQELLEVVKKKSGEIKVRNHGGVAFVPL 211
+++Q+L V K G + +++ V +VPL
Sbjct: 191 -NIFQDLQVVDKNSDGSVSIKDETSVRYVPL 220
>sp|Q43209|PIMT_WHEAT PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE (PROTEIN-BETA-ASPARTATE
METHYLTRANSFERASE) (PIMT) (PROTEIN L-ISOASPARTYL
METHYLTRANSFERASE) (L-ISOASPARTYL PROTEIN CARBOXYL
METHYLTRANSFERASE) >gi|7451057|pir||T06519 probable
protein-L-isoaspartate(D-aspartate) O-methyltransferase
(EC 2.1.1.77) - wheat >gi|414332|gb|AAA34297.1| (L07941)
L-isoaspartyl methyltransferase [Triticum aestivum]
Length = 230
Score = 147 bits (367), Expect = 1e-34
Identities = 90/216 (41%), Positives = 125/216 (57%), Gaps = 18/216 (8%)
Query: 8 ERWKRTVEMLEREGIIRSLEVKEAFLKYPRYMFVEDRYKSYAHIDEPLPIPAGQTVSAPH 67
E+ VE L++ G++R+ +V E R +FV + + Y D P+PI T+SAPH
Sbjct: 11 EKNNALVEYLKQYGVVRTDKVAEVMETIDRALFVPEGFTPYT--DSPMPIGYNATISAPH 68
Query: 68 MVAIMLEIAK--LKEGMNVLEVGTGSGWNAALISYIVKTD--VYSIERIPELVEFAKRNL 123
M A LE+ K L+ GM+ L+VG+GSG+ A + +V + IE IPELV + N+
Sbjct: 69 MHATCLELLKDYLQPGMHALDVGSGSGYLTACFAMMVGPEGRAVGIEHIPELVVASTENV 128
Query: 124 ERA--------GVKNVHVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLI 175
ER+ G + HV DG G+P APYD I V A AP++P PL+EQLKPGGR++
Sbjct: 129 ERSAAAALMKDGSLSFHV--SDGRLGWPDAAPYDAIHVGAAAPEIPRPLLEQLKPGGRMV 186
Query: 176 IPVGSYHLWQELLEVVKKKSGEIKVRNHGGVAFVPL 211
IPVG+Y Q+L + K G VRN V +VPL
Sbjct: 187 IPVGTYS--QDLQVIDKSADGSTSVRNDASVRYVPL 220
>sp|P24206|PIMT_ECOLI PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE (PROTEIN-BETA-ASPARTATE
METHYLTRANSFERASE) (PIMT) (PROTEIN L-ISOASPARTYL
METHYLTRANSFERASE) (L-ISOASPARTYL PROTEIN CARBOXYL
METHYLTRANSFERASE) >gi|78786|pir||JH0242
protein-L-isoaspartate(D-aspartate) O-methyltransferase
(EC 2.1.1.77) type II - Escherichia coli
>gi|147115|gb|AAA24302.1| (M63493) L-isoaspartyl protein
carboxyl methyltransferase [Escherichia coli]
>gi|882636|gb|AAA69253.1| (U29579) L-isoaspartyl protein
carboxyl methyltransferase type II [Escherichia coli]
>gi|1789100|gb|AAC75785.1| (AE000358) L-isoaspartate
protein carboxylmethyltransferase type II [Escherichia
coli K12]
Length = 208
Score = 135 bits (337), Expect = 4e-31
Identities = 79/204 (38%), Positives = 122/204 (59%), Gaps = 5/204 (2%)
Query: 9 RWKRTVEMLEREGIIRSLEVKEAFLKYPRYMFVEDRYKSYAHIDEPLPIPAGQTVSAPHM 68
R + ++ L +GI + +V A PR FV++ ++ A + LPI GQT+S P+M
Sbjct: 5 RVQALLDQLRAQGI-QDEQVLNALAAVPREKFVDEAFEQKAWDNIALPIGQGQTISQPYM 63
Query: 69 VAIMLEIAKLKEGMNVLEVGTGSGWNAALISYIVKTDVYSIERIPELVEFAKRNLERAGV 128
VA M E+ +L VLE+GTGSG+ A+++++V+ V S+ERI L A+R L+ +
Sbjct: 64 VARMTELLELTPQSRVLEIGTGSGYQTAILAHLVQ-HVCSVERIKGLQWQARRRLKNLDL 122
Query: 129 KNVHVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPVGSYHLWQELL 188
NV GDG +G+ +AP+D IIVTA P++P L+ QL GG L++PVG H + L
Sbjct: 123 HNVSTRHGDGWQGWQARAPFDAIIVTAAPPEIPTALMTQLDEGGILVLPVGEEH---QYL 179
Query: 189 EVVKKKSGEIKVRNHGGVAFVPLI 212
+ V+++ GE + V FVPL+
Sbjct: 180 KRVRRRGGEFIIDTVEAVRFVPLV 203
>pir||G82311 protein-L-isoaspartate O-methyltransferase VC0532 [imported] -
Vibrio cholerae (group O1 strain N16961)
>gi|9654959|gb|AAF93700.1| (AE004139)
protein-L-isoaspartate O-methyltransferase [Vibrio
cholerae]
Length = 208
Score = 132 bits (330), Expect = 2e-30
Identities = 78/201 (38%), Positives = 117/201 (57%), Gaps = 5/201 (2%)
Query: 12 RTVEMLEREGIIRSLEVKEAFLKYPRYMFVEDRYKSYAHIDEPLPIPAGQTVSAPHMVAI 71
R ++ L +GI S +V A PR FV A+ + LPI GQT+S P++VA
Sbjct: 8 RLIQFLTEQGIT-SPQVLAAIHALPREFFVAPAMMHQAYDNNALPIGQGQTISQPYIVAK 66
Query: 72 MLEIAKLKEGMNVLEVGTGSGWNAALISYIVKTDVYSIERIPELVEFAKRNLERAGVKNV 131
M E+ L VLE+GTGSG+ A+++ +V V+++ERI L AKR L++ + NV
Sbjct: 67 MTELLALTPETKVLEIGTGSGYQTAVLAKLVN-HVFTVERIKTLQWDAKRRLKQLDIYNV 125
Query: 132 HVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPVGSYHLWQELLEVV 191
GDG +G+P + P+D I+VTA A KVP+ L++QL GGR++IPVG ++ L +
Sbjct: 126 STKHGDGWQGWPARGPFDAILVTAAAAKVPQSLLDQLAEGGRMVIPVGED---EQYLYKI 182
Query: 192 KKKSGEIKVRNHGGVAFVPLI 212
++ G+ V FVPL+
Sbjct: 183 VRQGGQFISERVEAVRFVPLV 203
>pir||F83193 L-isoaspartate protein carboxylmethyltransferase type II PA3624
[imported] - Pseudomonas aeruginosa (strain PAO1)
>gi|9949782|gb|AAG07012.1|AE004782_10 (AE004782)
L-isoaspartate protein carboxylmethyltransferase type II
[Pseudomonas aeruginosa]
Length = 211
Score = 131 bits (325), Expect = 1e-29
Identities = 80/203 (39%), Positives = 124/203 (60%), Gaps = 5/203 (2%)
Query: 11 KRTVEMLEREGIIRSLEVKEAFLKYPRYMFVEDRYKSYAHIDEPLPIPAGQTVSAPHMVA 70
+R ++ L EG+ + V E + PR++FV++ A+ D LPI QT+S P MVA
Sbjct: 8 ERLIQRLYEEGLSNA-HVLEVIRRTPRHLFVDEALSHRAYEDTALPIGHNQTISQPFMVA 66
Query: 71 IMLEIAKLKEGMN-VLEVGTGSGWNAALISYIVKTDVYSIERIPELVEFAKRNLERAGVK 129
M E+ ++ V+E+GTGSG+ A+++ +V+ V+S+ERI L + AK L ++
Sbjct: 67 RMTELLLAAGPLDKVMEIGTGSGYQTAVLAQLVER-VFSVERIQALQDKAKERLAELNLR 125
Query: 130 NVHVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPVGSYHLWQELLE 189
NV GDG +G+ APY+ IIVTA A +VP+ L++QL PGGRL+IPVG + Q+L+
Sbjct: 126 NVVFRWGDGWEGWSALAPYNGIIVTAAATEVPQSLLDQLAPGGRLVIPVGGGEV-QQLML 184
Query: 190 VVKKKSGEIKVRNHGGVAFVPLI 212
+V+ + G + V FVPL+
Sbjct: 185 IVRTEDG-FSRQVLDSVRFVPLL 206
>sp|P23506|PIMT_MOUSE PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE
(PROTEIN-BETA-ASPARTATE METHYLTRANSFERASE) (PIMT)
(PROTEIN L-ISOASPARTYL/D-ASPARTYL METHYLTRANSFERASE)
(L-ISOASPARTYL PROTEIN CARBOXYL METHYLTRANSFERASE)
>gi|110866|pir||JC1248
protein-L-isoaspartate(D-aspartate) O-methyltransferase
(EC 2.1.1.77) - mouse
Length = 227
Score = 119 bits (295), Expect = 3e-26
Identities = 79/207 (38%), Positives = 115/207 (55%), Gaps = 13/207 (6%)
Query: 14 VEMLEREGIIRSLEVKEAFLKYPRYMFVEDRYKSYAHIDEPLPIPAGQTVSAPHMVAIML 73
+ L + GII++ +V E L R + KS ++D P I T+SAPHM A L
Sbjct: 14 IHNLRKNGIIKTDKVFEVMLATDRSHYA----KSNPYMDSPQSIGFQATISAPHMHAYAL 69
Query: 74 EIA--KLKEGMNVLEVGTGSGWNAALISYIVKTD--VYSIERIPELVEFAKRNLER---- 125
E+ +L EG L+VG+GSG A + +V V I+ I ELV+ + N+++
Sbjct: 70 ELLFDQLHEGAKALDVGSGSGILTACFARMVGNSGKVIGIDHIKELVDDSITNVKKDDPM 129
Query: 126 -AGVKNVHVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPVGSYHLW 184
V +++GDG G+ +APYD I V A AP VP+ L++QLKPGGRLI+PVG
Sbjct: 130 LLSSGRVRLVVGDGRMGYAEEAPYDAIHVGAAAPVVPQALIDQLKPGGRLILPVGPAGGN 189
Query: 185 QELLEVVKKKSGEIKVRNHGGVAFVPL 211
Q L + K + G +K++ GV +VPL
Sbjct: 190 QMLEQYDKLQDGSVKMKPLMGVIYVPL 216
>sp|P15246|PIMT_BOVIN PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE
(PROTEIN-BETA-ASPARTATE METHYLTRANSFERASE) (PIMT)
(PROTEIN L-ISOASPARTYL/D-ASPARTYL METHYLTRANSFERASE)
(L-ISOASPARTYL PROTEIN CARBOXYL METHYLTRANSFERASE)
>gi|89737|pir||A34242
protein-L-isoaspartate(D-aspartate) O-methyltransferase
(EC 2.1.1.77) form I - bovine
Length = 226
Score = 117 bits (290), Expect = 1e-25
Identities = 78/207 (37%), Positives = 113/207 (53%), Gaps = 13/207 (6%)
Query: 14 VEMLEREGIIRSLEVKEAFLKYPRYMFVEDRYKSYAHIDEPLPIPAGQTVSAPHMVAIML 73
+ L + GII++ +V E L R + K ++D P I T+SAPHM A L
Sbjct: 13 IHNLRKNGIIKTDKVFEVMLATDRSHYA----KCNPYMDSPQSIGFQATISAPHMHAYAL 68
Query: 74 EIA--KLKEGMNVLEVGTGSGWNAALISYIVKTD--VYSIERIPELVEFAKRNLER---- 125
E+ +L EG L+VG+GSG A + +V V I+ I ELV+ + N+ +
Sbjct: 69 ELLFDQLNEGAKALDVGSGSGILTACFARMVGPSGKVIGIDHIKELVDDSINNVRKDDPM 128
Query: 126 -AGVKNVHVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPVGSYHLW 184
V +++GDG G+ +APYD I V A AP VP+ L++QLKPGGRLI+PVG
Sbjct: 129 LLSSGRVQLVVGDGRMGYAAEAPYDAIHVGAAAPVVPQALIDQLKPGGRLILPVGPAGGN 188
Query: 185 QELLEVVKKKSGEIKVRNHGGVAFVPL 211
Q L + K + G +K++ GV +VPL
Sbjct: 189 QMLEQYDKLQDGSVKMKPLMGVIYVPL 215
>gi|6981338 protein-L-isoaspartate (D-aspartate) O-methyltransferase [Rattus
norvegicus] >gi|130219|sp|P22062|PIMT_RAT
PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE
(PROTEIN-BETA-ASPARTATE METHYLTRANSFERASE) (PIMT)
(PROTEIN L-ISOASPARTYL/D-ASPARTYL METHYLTRANSFERASE)
(L-ISOASPARTYL PROTEIN CARBOXYL METHYLTRANSFERASE)
>gi|112228|pir||A32449
protein-L-isoaspartate(D-aspartate) O-methyltransferase
(EC 2.1.1.77) - rat >gi|603467|gb|AAA60742.1| (M26686)
protein carboxyl methyltransferase [Rattus norvegicus]
Length = 227
Score = 117 bits (290), Expect = 1e-25
Identities = 79/207 (38%), Positives = 114/207 (54%), Gaps = 13/207 (6%)
Query: 14 VEMLEREGIIRSLEVKEAFLKYPRYMFVEDRYKSYAHIDEPLPIPAGQTVSAPHMVAIML 73
+ L + GII++ +V E L R + KS ++D P I T+SAPHM A L
Sbjct: 14 IHNLRKNGIIKTDKVFEVMLATDRSHYA----KSNPYMDSPQSIGFQATISAPHMHAYAL 69
Query: 74 EIA--KLKEGMNVLEVGTGSGWNAALISYIV--KTDVYSIERIPELVEFAKRNLER---- 125
E+ +L EG +VG+GSG A + +V V I+ I ELV+ + N+++
Sbjct: 70 ELLFDQLHEGAKAPDVGSGSGILTACFARMVGHSGKVIGIDHIKELVDDSITNVKKDDPM 129
Query: 126 -AGVKNVHVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPVGSYHLW 184
V +++GDG GF +APYD I V A AP VP+ L++QLKPGGRLI+PVG
Sbjct: 130 LLSSGRVRLVVGDGRMGFAEEAPYDAIHVGAAAPVVPQALIDQLKPGGRLILPVGPAGGN 189
Query: 185 QELLEVVKKKSGEIKVRNHGGVAFVPL 211
Q L + K + G +K++ GV +VPL
Sbjct: 190 QMLEQYDKLQDGSVKMKPLMGVIYVPL 216
>gi|6679217 protein-L-isoaspartate (D-aspartate) O-methyltransferase 1; protein
carboxyl methyltransferase [Mus musculus]
>gi|200255|gb|AAA92742.1| (M60320) protein carboxyl
methyltransferase [Mus musculus]
Length = 227
Score = 117 bits (290), Expect = 1e-25
Identities = 78/207 (37%), Positives = 114/207 (54%), Gaps = 13/207 (6%)
Query: 14 VEMLEREGIIRSLEVKEAFLKYPRYMFVEDRYKSYAHIDEPLPIPAGQTVSAPHMVAIML 73
+ L + GII++ +V E L R + KS ++D P T+SAPHM A L
Sbjct: 14 IHNLRKNGIIKTDKVFEVMLATDRSHYA----KSNPYMDSPQSTGFQATISAPHMHAYAL 69
Query: 74 EIA--KLKEGMNVLEVGTGSGWNAALISYIVKTD--VYSIERIPELVEFAKRNLER---- 125
E+ +L EG L+VG+GSG A + +V V I+ I ELV+ + N+++
Sbjct: 70 ELLFDQLHEGAKALDVGSGSGILTACFARMVGNSGKVIGIDHIKELVDDSITNVKKDDPM 129
Query: 126 -AGVKNVHVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPVGSYHLW 184
V +++GDG G+ +APYD I V A AP VP+ L++QLKPGGRLI+PVG
Sbjct: 130 LLSSGRVRLVVGDGRMGYAEEAPYDAIHVGAAAPVVPQALIDQLKPGGRLILPVGPAGGN 189
Query: 185 QELLEVVKKKSGEIKVRNHGGVAFVPL 211
Q L + K + G +K++ GV +VPL
Sbjct: 190 QMLEQYDKLQDGSVKMKPLMGVIYVPL 216
>pir||A43292 protein-L-isoaspartate(D-aspartate) O-methyltransferase (EC
2.1.1.77) form II - bovine
Length = 227
Score = 117 bits (290), Expect = 1e-25
Identities = 78/207 (37%), Positives = 113/207 (53%), Gaps = 13/207 (6%)
Query: 14 VEMLEREGIIRSLEVKEAFLKYPRYMFVEDRYKSYAHIDEPLPIPAGQTVSAPHMVAIML 73
+ L + GII++ +V E L R + K ++D P I T+SAPHM A L
Sbjct: 13 IHNLRKNGIIKTDKVFEVMLATDRSHYA----KCNPYMDSPQSIGFQATISAPHMHAYAL 68
Query: 74 EIA--KLKEGMNVLEVGTGSGWNAALISYIVKTD--VYSIERIPELVEFAKRNLER---- 125
E+ +L EG L+VG+GSG A + +V V I+ I ELV+ + N+ +
Sbjct: 69 ELLFDQLNEGAKALDVGSGSGILTACFARMVGPSGKVIGIDHIKELVDDSINNVRKDDPM 128
Query: 126 -AGVKNVHVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPVGSYHLW 184
V +++GDG G+ +APYD I V A AP VP+ L++QLKPGGRLI+PVG
Sbjct: 129 LLSSGRVQLVVGDGRMGYAAEAPYDAIHVGAAAPVVPQALIDQLKPGGRLILPVGPAGGN 188
Query: 185 QELLEVVKKKSGEIKVRNHGGVAFVPL 211
Q L + K + G +K++ GV +VPL
Sbjct: 189 QMLEQYDKLQDGSVKMKPLMGVIYVPL 215
>sp|Q56308|PIMT_THEMA PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE (PROTEIN-BETA-ASPARTATE
METHYLTRANSFERASE) (PIMT) (PROTEIN L-ISOASPARTYL
METHYLTRANSFERASE) (L-ISOASPARTYL PROTEIN CARBOXYL
METHYLTRANSFERASE) >gi|7462866|pir||G72342
L-isoaspartate(D-aspartate) O-methyltransferase -
Thermotoga maritima (strain MSB8)
>gi|940145|gb|AAA96385.1| (U30501) orf1; similar to
protein-L-isoaspartate(D-aspartate)
O-methyltransferases, Swiss-Prot Accession Number
P24206; ORF1 protein; Method: conceptual translation
supplied by author [Thermotoga maritima]
>gi|4981228|gb|AAD35786.1|AE001742_1 (AE001742)
L-isoaspartate(D-aspartate) O-methyltransferase
[Thermotoga maritima]
Length = 317
Score = 117 bits (290), Expect = 1e-25
Identities = 72/170 (42%), Positives = 105/170 (61%), Gaps = 9/170 (5%)
Query: 16 MLEREGIIRSLEVKEAFLKYPRYMFVEDRYK-SYAHIDEPL-PIPAGQ---TVSAPHMVA 70
+L++ G+ S + +AFL+ PR F+ Y SY + D L G+ T S P ++A
Sbjct: 8 ILKKYGV--SDHIAKAFLEIPREEFLTKSYPLSYVYEDIVLVSYDDGEEYSTSSQPSLMA 65
Query: 71 IMLEIAKLKEGMNVLEVGTGSGWNAALISYIV--KTDVYSIERIPELVEFAKRNLERAGV 128
+ +E L +GM VLE+G G+G+NAA++S +V K V S+E ++ E AKRN+ER G+
Sbjct: 66 LFMEWVGLDKGMRVLEIGGGTGYNAAVMSRVVGEKGLVVSVEYSRKICEIAKRNVERLGI 125
Query: 129 KNVHVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPV 178
+NV + GDG G P +PYDVI VT G +VPE QLK GGR+I+P+
Sbjct: 126 ENVIFVCGDGYYGVPEFSPYDVIFVTVGVDEVPETWFTQLKEGGRVIVPI 175
>gi|4885539 protein-L-isoaspartate (D-aspartate) O-methyltransferase [Homo
sapiens] >gi|1332399|dbj|BAA05028.1| (D25545) PIMT
isozyme I [Homo sapiens] >gi|1332403|dbj|BAA05030.1|
(D25547) PIMT isozyme I [Homo sapiens]
Length = 227
Score = 117 bits (290), Expect = 1e-25
Identities = 79/207 (38%), Positives = 113/207 (54%), Gaps = 13/207 (6%)
Query: 14 VEMLEREGIIRSLEVKEAFLKYPRYMFVEDRYKSYAHIDEPLPIPAGQTVSAPHMVAIML 73
+ L + GII++ +V E L R + K ++D P I T+SAPHM A L
Sbjct: 14 IHNLRKNGIIKTDKVFEVMLATDRSHYA----KCNPYMDSPQSIGFQATISAPHMHAYAL 69
Query: 74 EIA--KLKEGMNVLEVGTGSGWNAALISYIVKTD--VYSIERIPELVEFAKRNLER---- 125
E+ +L EG L+VG+GSG A + +V V I+ I ELV+ + N+ +
Sbjct: 70 ELLFDQLHEGAKALDVGSGSGILTACFARMVGCTGKVIGIDHIKELVDDSVNNVRKDDPT 129
Query: 126 -AGVKNVHVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPVGSYHLW 184
V +++GDG G+ +APYD I V A AP VP+ L++QLKPGGRLI+PVG
Sbjct: 130 LLSSGRVQLVVGDGRMGYAEEAPYDAIHVGAAAPVVPQALIDQLKPGGRLILPVGPAGGN 189
Query: 185 QELLEVVKKKSGEIKVRNHGGVAFVPL 211
Q L + K + G IK++ GV +VPL
Sbjct: 190 QMLEQYDKLQDGSIKMKPLMGVIYVPL 216
>pir||JH0624 protein-L-isoaspartate(D-aspartate) O-methyltransferase (EC
2.1.1.77) splice form II - human
>gi|180637|gb|AAA90934.1| (M93008)
L-isoaspartyl/D-aspartyl protein carboxyl
methyltransferase [Homo sapiens]
>gi|474984|dbj|BAA02991.1| (D13892) carboxyl
methyltransferase [Homo sapiens]
>gi|1332401|dbj|BAA05029.1| (D25546) PIMT isozyme II
[Homo sapiens]
Length = 228
Score = 117 bits (290), Expect = 1e-25
Identities = 79/207 (38%), Positives = 113/207 (54%), Gaps = 13/207 (6%)
Query: 14 VEMLEREGIIRSLEVKEAFLKYPRYMFVEDRYKSYAHIDEPLPIPAGQTVSAPHMVAIML 73
+ L + GII++ +V E L R + K ++D P I T+SAPHM A L
Sbjct: 14 IHNLRKNGIIKTDKVFEVMLATDRSHYA----KCNPYMDSPQSIGFQATISAPHMHAYAL 69
Query: 74 EIA--KLKEGMNVLEVGTGSGWNAALISYIVKTD--VYSIERIPELVEFAKRNLER---- 125
E+ +L EG L+VG+GSG A + +V V I+ I ELV+ + N+ +
Sbjct: 70 ELLFDQLHEGAKALDVGSGSGILTACFARMVGCTGKVIGIDHIKELVDDSVNNVRKDDPT 129
Query: 126 -AGVKNVHVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPVGSYHLW 184
V +++GDG G+ +APYD I V A AP VP+ L++QLKPGGRLI+PVG
Sbjct: 130 LLSSGRVQLVVGDGRMGYAEEAPYDAIHVGAAAPVVPQALIDQLKPGGRLILPVGPAGGN 189
Query: 185 QELLEVVKKKSGEIKVRNHGGVAFVPL 211
Q L + K + G IK++ GV +VPL
Sbjct: 190 QMLEQYDKLQDGSIKMKPLMGVIYVPL 216
>gi|11417533 protein-L-isoaspartate (D-aspartate) O-methyltransferase [Homo
sapiens]
Length = 251
Score = 117 bits (290), Expect = 1e-25
Identities = 79/207 (38%), Positives = 113/207 (54%), Gaps = 13/207 (6%)
Query: 14 VEMLEREGIIRSLEVKEAFLKYPRYMFVEDRYKSYAHIDEPLPIPAGQTVSAPHMVAIML 73
+ L + GII++ +V E L R + K ++D P I T+SAPHM A L
Sbjct: 38 IHNLRKNGIIKTDKVFEVMLATDRSHYA----KCNPYMDSPQSIGFQATISAPHMHAYAL 93
Query: 74 EIA--KLKEGMNVLEVGTGSGWNAALISYIVKTD--VYSIERIPELVEFAKRNLER---- 125
E+ +L EG L+VG+GSG A + +V V I+ I ELV+ + N+ +
Sbjct: 94 ELLFDQLHEGAKALDVGSGSGILTACFARMVGCTGKVIGIDHIKELVDDSVNNVRKDDPT 153
Query: 126 -AGVKNVHVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPVGSYHLW 184
V +++GDG G+ +APYD I V A AP VP+ L++QLKPGGRLI+PVG
Sbjct: 154 LLSSGRVQLVVGDGRMGYAEEAPYDAIHVGAAAPVVPQALIDQLKPGGRLILPVGPAGGN 213
Query: 185 QELLEVVKKKSGEIKVRNHGGVAFVPL 211
Q L + K + G IK++ GV +VPL
Sbjct: 214 QMLEQYDKLQDGSIKMKPLMGVIYVPL 240
>prf||2110330A isoAsp protein carboxyl methyltransferase [Homo sapiens]
Length = 230
Score = 116 bits (289), Expect = 2e-25
Identities = 81/210 (38%), Positives = 114/210 (53%), Gaps = 19/210 (9%)
Query: 14 VEMLEREGIIRSLEVKEAFLKYPRYMFVEDRY---KSYAHIDEPLPIPAGQTVSAPHMVA 70
+ L + GII++ +V E YM DR K ++D P I T+SAPHM A
Sbjct: 14 IHNLRKNGIIKTDKVFE-------YMLATDRSHYAKCNPYMDSPQSIGFQATISAPHMHA 66
Query: 71 IMLEIA--KLKEGMNVLEVGTGSGWNAALISYIVKTD--VYSIERIPELVEFAKRNLER- 125
LE+ +L EG L+VG+GSG A + +V V I+ I ELV+ + N+ +
Sbjct: 67 YALELLFDQLHEGAKALDVGSGSGILTACFARMVGCTGKVIGIDHIKELVDDSVNNVRKD 126
Query: 126 ----AGVKNVHVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPVGSY 181
V +++GDG G+ +APYD I V A AP VP+ L++QLKPGGRLI+PVG
Sbjct: 127 DPTLLSSGRVQLVVGDGRMGYAEEAPYDAIHVGAAAPVVPQALIDQLKPGGRLILPVGPA 186
Query: 182 HLWQELLEVVKKKSGEIKVRNHGGVAFVPL 211
Q L + K + G IK++ GV +VPL
Sbjct: 187 GGNQMLEQYDKLQDGSIKMKPLMGVIYVPL 216
>sp|P22061|PIMT_HUMAN PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE
(PROTEIN-BETA-ASPARTATE METHYLTRANSFERASE) (PIMT)
(PROTEIN L-ISOASPARTYL/D-ASPARTYL METHYLTRANSFERASE)
(L-ISOASPARTYL PROTEIN CARBOXYL METHYLTRANSFERASE)
Length = 227
Score = 116 bits (289), Expect = 2e-25
Identities = 79/207 (38%), Positives = 113/207 (54%), Gaps = 13/207 (6%)
Query: 14 VEMLEREGIIRSLEVKEAFLKYPRYMFVEDRYKSYAHIDEPLPIPAGQTVSAPHMVAIML 73
+ L + GII++ +V E L R + K ++D P I T+SAPHM A L
Sbjct: 14 IHNLRKNGIIKTDKVFEVMLATDRSHYA----KCNPYMDSPQSIGFQATISAPHMHAYAL 69
Query: 74 EIA--KLKEGMNVLEVGTGSGWNAALISYIVKTD--VYSIERIPELVEFAKRNLER---- 125
E+ +L EG L+VG+GSG A + +V V I+ I ELV+ + N+ +
Sbjct: 70 ELLFDQLHEGAKALDVGSGSGILTACFARMVGCTGKVIGIDHIKELVDDSINNVRKDDPT 129
Query: 126 -AGVKNVHVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPVGSYHLW 184
V +++GDG G+ +APYD I V A AP VP+ L++QLKPGGRLI+PVG
Sbjct: 130 LLSSGRVQLVVGDGRMGYAEEAPYDAIHVGAAAPVVPQALIDQLKPGGRLILPVGPAGGN 189
Query: 185 QELLEVVKKKSGEIKVRNHGGVAFVPL 211
Q L + K + G IK++ GV +VPL
Sbjct: 190 QMLEQYDKLQDGSIKMKPLMGVIYVPL 216
>pir||A34489 protein-L-isoaspartate(D-aspartate) O-methyltransferase (EC
2.1.1.77) splice form I - human
Length = 226
Score = 116 bits (287), Expect = 3e-25
Identities = 78/207 (37%), Positives = 113/207 (53%), Gaps = 13/207 (6%)
Query: 14 VEMLEREGIIRSLEVKEAFLKYPRYMFVEDRYKSYAHIDEPLPIPAGQTVSAPHMVAIML 73
+ L + GI+++ +V E L R + K ++D P I T+SAPHM A L
Sbjct: 13 IHNLRKNGILKTDKVFEVMLATDRSHYA----KCNPYMDSPQSIGFQATISAPHMHAYAL 68
Query: 74 EIA--KLKEGMNVLEVGTGSGWNAALISYIVKTD--VYSIERIPELVEFAKRNLER---- 125
E+ +L EG L+VG+GSG A + +V V I+ I ELV+ + N+ +
Sbjct: 69 ELLFDQLHEGAKALDVGSGSGILTACFARMVGQTGKVIGIDHIKELVDDSINNVRKDDPT 128
Query: 126 -AGVKNVHVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPVGSYHLW 184
V +++GDG G+ +APYD I V A AP VP+ L++QLKPGGRLI+PVG
Sbjct: 129 LLSSGRVQLVVGDGRMGYAEEAPYDAIHVGAAAPVVPQALIDQLKPGGRLILPVGPAGGN 188
Query: 185 QELLEVVKKKSGEIKVRNHGGVAFVPL 211
Q L + K + G IK++ GV +VPL
Sbjct: 189 QMLEQYDKLQDGSIKMKPLMGVIYVPL 215
>sp|Q92047|PIMT_BRARE PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE
(PROTEIN-BETA-ASPARTATE METHYLTRANSFERASE) (PIMT)
(PROTEIN L-ISOASPARTYL/D-ASPARTYL METHYLTRANSFERASE)
(L-ISOASPARTYL PROTEIN CARBOXYL METHYLTRANSFERASE)
>gi|1255009|gb|AAA96020.1| (U37434) L-isoaspartate
(D-aspartate) O-methyltransferase [Danio rerio]
Length = 228
Score = 116 bits (287), Expect = 3e-25
Identities = 82/207 (39%), Positives = 111/207 (53%), Gaps = 13/207 (6%)
Query: 14 VEMLEREGIIRSLEVKEAFLKYPRYMFVEDRYKSYAHIDEPLPIPAGQTVSAPHMVAIML 73
V L + GII+S V E L R F + ++D P I T+SAPHM A L
Sbjct: 14 VNNLRKNGIIKSDRVYEVMLATDRSHFS----RCNPYMDSPQSIGYQATISAPHMHAYAL 69
Query: 74 EIAK--LKEGMNVLEVGTGSGWNAALISYIVKTD--VYSIERIPELVEFAKRNLERAGVK 129
E+ L EG L+VG+GSG + S +V V I+ I ELVE + N+++
Sbjct: 70 ELLHDHLYEGAKALDVGSGSGILSVCFSRMVGPTGKVIGIDHIKELVEDSIANVKKDDPS 129
Query: 130 -----NVHVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPVGSYHLW 184
+ +I+GDG GF +APYD I V A AP VP+ L++QLKPGGRLI+PVG
Sbjct: 130 LITSGRIKLIVGDGRMGFTEEAPYDAIHVGAAAPTVPQALLDQLKPGGRLILPVGPAGGN 189
Query: 185 QELLEVVKKKSGEIKVRNHGGVAFVPL 211
Q L + K + G K++ GV +VPL
Sbjct: 190 QMLEQYDKLEDGSTKMKPLMGVIYVPL 216
>gb|AAF52012.1| (AE003602) Pcmt gene product [Drosophila melanogaster]
Length = 226
Score = 115 bits (284), Expect = 6e-25
Identities = 77/212 (36%), Positives = 113/212 (52%), Gaps = 18/212 (8%)
Query: 14 VEMLEREGIIRSLEVKEAFLKYPRYMFVEDRYKSYAHIDEPLPIPAGQTVSAPHMVAIML 73
+ L+ G+I S V +A + R + ++D P PI G T+SAPHM A L
Sbjct: 14 IRQLKDHGVIASDAVAQAMKETDRKHYSPRN----PYMDAPQPIGGGVTISAPHMHAFAL 69
Query: 74 EIAK--LKEGMNVLEVGTGSGWNAALISYIVK-------TDVYSIERIPELVEFAKRNL- 123
E + LK G +L+VG+GSG+ A +K T + IE ELV +K NL
Sbjct: 70 EYLRDHLKPGARILDVGSGSGYLTACFYRYIKAKGVDADTRIVGIEHQAELVRRSKANLN 129
Query: 124 --ERAGVKNVHVIL--GDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPVG 179
+R+ + + +++ GDG KG+PP APY+ I V A AP P L+ QL GGRLI+PVG
Sbjct: 130 TDDRSMLDSGQLLIVEGDGRKGYPPNAPYNAIHVGAAAPDTPTELINQLASGGRLIVPVG 189
Query: 180 SYHLWQELLEVVKKKSGEIKVRNHGGVAFVPL 211
Q + + K +G++++ GV +VPL
Sbjct: 190 PDGGSQYMQQYDKDANGKVEMTRLMGVMYVPL 221
>sp|Q27869|PIMT_DROME PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE
(PROTEIN-BETA-ASPARTATE METHYLTRANSFERASE) (PIMT)
(PROTEIN L-ISOASPARTYL/D-ASPARTYL METHYLTRANSFERASE)
(L-ISOASPARTYL PROTEIN CARBOXYL METHYLTRANSFERASE)
>gi|1051233|gb|AAA80540.1| (U37432) protein D-aspartyl,
L-isoaspartyl methyltransferase [Drosophila
melanogaster] >gi|1171337|gb|AAA86272.1| (U43737)
isoaspartyl methyltransferase [Drosophila melanogaster]
Length = 226
Score = 114 bits (283), Expect = 8e-25
Identities = 77/212 (36%), Positives = 112/212 (52%), Gaps = 18/212 (8%)
Query: 14 VEMLEREGIIRSLEVKEAFLKYPRYMFVEDRYKSYAHIDEPLPIPAGQTVSAPHMVAIML 73
+ L+ G+I S V +A + R + ++D P PI G T+SAPHM A L
Sbjct: 14 IRQLKDHGVIASDAVAQAMKETDRKHYSPRN----PYMDAPQPIGGGVTISAPHMHAFAL 69
Query: 74 EIAK--LKEGMNVLEVGTGSGWNAALISYIVK-------TDVYSIERIPELVEFAKRNL- 123
E + LK G +L+VG+GSG+ A +K T + IE ELV K NL
Sbjct: 70 EYLRDHLKPGARILDVGSGSGYLTACFYRYIKAKGVDADTRIVGIEHQAELVRRTKANLN 129
Query: 124 --ERAGVKNVHVIL--GDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPVG 179
+R+ + + +++ GDG KG+PP APY+ I V A AP P L+ QL GGRLI+PVG
Sbjct: 130 TDDRSMLDSGQLLIVEGDGRKGYPPNAPYNAIHVGAAAPDTPTELINQLASGGRLIVPVG 189
Query: 180 SYHLWQELLEVVKKKSGEIKVRNHGGVAFVPL 211
Q + + K +G++++ GV +VPL
Sbjct: 190 PDGGSQYMQQYDKDANGKVEMTRLMGVMYVPL 221
>pir||C82754 L-isoaspartate O-methyltransferase XF0857 [imported] - Xylella
fastidiosa (strain 9a5c)
>gi|9105765|gb|AAF83667.1|AE003925_7 (AE003925)
L-isoaspartate O-methyltransferase [Xylella fastidiosa]
Length = 225
Score = 113 bits (281), Expect = 1e-24
Identities = 75/201 (37%), Positives = 114/201 (56%), Gaps = 4/201 (1%)
Query: 12 RTVEMLEREGIIRSLEVKEAFLKYPRYMFVEDRYKSYAHIDEPLPIPAGQTVSAPHMVAI 71
R VE L RE I+ V PR++F+++ A+ D LPI GQT+S P +VA
Sbjct: 24 RLVERL-RECGIQDERVLTTIRIVPRHLFIDEALALRAYEDTALPIGHGQTISQPWVVAR 82
Query: 72 MLEIAKLKEGMNVLEVGTGSGWNAALISYIVKTDVYSIERIPELVEFAKRNLERAGVKNV 131
M E +LE+GTGSG+ +A+++ + +VY+IERI +L+ A++ + G+K +
Sbjct: 83 MTEAVMQVAPKKILEIGTGSGYQSAILASL-GLEVYTIERIGKLLRQARKRFRQLGIK-I 140
Query: 132 HVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPVGSYHLWQELLEVV 191
DGS G+ APY+ I+VTA AP + + L+EQL GGRL+ PVG+ Q L+++
Sbjct: 141 RSKHDDGSIGWTEHAPYNAILVTAAAPTLIDTLIEQLAIGGRLVAPVGTAS-EQALVQLT 199
Query: 192 KKKSGEIKVRNHGGVAFVPLI 212
+ G I V FV L+
Sbjct: 200 RTIDGNITHEILEPVTFVSLL 220
>emb|CAB92590.1| (AL356812) putative O-methyltransferase. [Streptomyces coelicolor
A3(2)]
Length = 696
Score = 112 bits (278), Expect = 3e-24
Identities = 66/173 (38%), Positives = 102/173 (58%), Gaps = 8/173 (4%)
Query: 14 VEMLEREGIIRSLEVKEAFLKYPRYMFVEDRYKSYAHIDEPLPIP---AGQTVSA---PH 67
++ L G +R+ V+EA PR++FV + A+ + P+ +G+++S P
Sbjct: 302 IDHLVETGCVRTPRVEEAMRTVPRHLFVPNAPLEKAYGNAPVDTKFDGSGRSISCASQPD 361
Query: 68 MVAIMLEIAKLKEGMNVLEVGTGSGWNAALISYIVKTD--VYSIERIPELVEFAKRNLER 125
+VA+MLE ++ G +LE+G G+G+NA L+ Y+V V +I+ ++V A+ L
Sbjct: 362 IVAMMLEQLDVQPGQKILELGAGTGFNAGLLGYLVGETGHVTTIDVDEDIVAGARGGLAA 421
Query: 126 AGVKNVHVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPV 178
AG+ NV VILGDG+ G P APYD I T GA VP ++QL PGGRL+ P+
Sbjct: 422 AGIHNVEVILGDGAVGHTPNAPYDRIEATVGAHGVPHAWLDQLAPGGRLLTPL 474
>pir||T50917 hypothetical protein pcm [imported] - Rubrivivax gelatinosus
>gi|7416821|dbj|BAA94070.1| (AB034704) similar to
L-isoaspartyl protein carboxyl methyltransferase of
Escherichia coli [Rubrivivax gelatinosus]
Length = 270
Score = 112 bits (278), Expect = 3e-24
Identities = 75/209 (35%), Positives = 112/209 (52%), Gaps = 10/209 (4%)
Query: 11 KRTVEMLEREGIIRSLEVKEAFLKYPRYMFVEDRYKSYAHIDEPLPIPAGQTVSAPHMVA 70
+R V L +G+ R V AF PR+ FV+ + A+ D LPI GQT+S P +V
Sbjct: 59 ERMVARLHADGL-RCEPVLRAFAAVPRHHFVDSALATQAYEDTSLPIGLGQTISKPSVVG 117
Query: 71 IMLEI-------AKLKEGMNVLEVGTGSGWNAALISYIVKTDVYSIERIPELVEFAKRNL 123
ML + A VLE+GTG G+ AAL++ I K V SIER+ L + A+ NL
Sbjct: 118 RMLALLFGGERAAAAGHLGRVLEIGTGCGYQAALLAQISKR-VVSIERLKPLHDKARDNL 176
Query: 124 ERAGVK-NVHVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPVGSYH 182
+ ++ ++ GDG G P APYD I+ AG +P+ ++QL GGRL+ P+
Sbjct: 177 AASRHPGDLRLLYGDGRLGHAPLAPYDSIVAAAGGEDIPQAWLDQLAEGGRLVAPMHDPA 236
Query: 183 LWQELLEVVKKKSGEIKVRNHGGVAFVPL 211
++L V+ ++ ++ + H V FVPL
Sbjct: 237 AGGQVLVVIDRRPEGLRRQVHDAVHFVPL 265
>pir||I56505 protein-L-isoaspartate(D-aspartate) O-methyltransferase (EC
2.1.1.77) - black rat >gi|220787|dbj|BAA02034.1|
(D11475) isoaspartyl protein carboxyl methyltransferase
[Rattus norvegicus]
Length = 196
Score = 111 bits (274), Expect = 9e-24
Identities = 71/175 (40%), Positives = 100/175 (56%), Gaps = 9/175 (5%)
Query: 46 KSYAHIDEPLPIPAGQTVSAPHMVAIMLEIA--KLKEGMNVLEVGTGSGWNAALISYIV- 102
KS ++D P I T+SAPHM A LE+ +L EG +VG+GSG A + +V
Sbjct: 11 KSNPYMDSPQSIGFQATISAPHMHAYALELLFDQLHEGAKAPDVGSGSGILTACFARMVG 70
Query: 103 -KTDVYSIERIPELVEFAKRNLER-----AGVKNVHVILGDGSKGFPPKAPYDVIIVTAG 156
V I+ I ELV+ + N+++ V +++GDG GF +APYD I V A
Sbjct: 71 HSGKVIGIDHIKELVDDSITNVKKDDPMLLSSGRVRLVVGDGRMGFAEEAPYDAIHVGAA 130
Query: 157 APKVPEPLVEQLKPGGRLIIPVGSYHLWQELLEVVKKKSGEIKVRNHGGVAFVPL 211
AP VP+ L++QLKPGGRLI+PVG Q L + K + G +K++ GV +VPL
Sbjct: 131 APVVPQALIDQLKPGGRLILPVGPAGGNQMLEQYDKLQDGSVKMKPLMGVIYVPL 185
>sp|P56133|PIMT_HELPY PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE (PROTEIN-BETA-ASPARTATE
METHYLTRANSFERASE) (PIMT) (PROTEIN L-ISOASPARTYL
METHYLTRANSFERASE) (L-ISOASPARTYL PROTEIN CARBOXYL
METHYLTRANSFERASE) >gi|7451064|pir||C64565
L-isoaspartyl-protein carboxyl methyltransferase -
Helicobacter pylori (strain 26695)
>gi|2313465|gb|AAD07431.1| (AE000553)
L-isoaspartyl-protein carboxyl methyltransferase (pcm)
[Helicobacter pylori 26695]
Length = 209
Score = 107 bits (264), Expect = 1e-22
Identities = 62/175 (35%), Positives = 106/175 (60%), Gaps = 3/175 (1%)
Query: 27 EVKEAFLKYPRYMFVEDRYKSYAHIDEPLPIPAGQTVSAPHMVAIMLEIAKLKEGMNVLE 86
+V+EA R +FV +K +A+ L + A Q +S+P VA M + ++ +VLE
Sbjct: 22 KVREAMESIEREVFVPAPFKHFAYTLNALSMQAQQYISSPLTVAKMTQYLEIDHVDSVLE 81
Query: 87 VGTGSGWNAALISYIVKTDVYSIERIPELVEFAKRNLERAGVKNVHVILGDGSKGFPPKA 146
+G GSG+ AA++S I + V+SIERI L A+ L+ G+ NVHV DG+KG+ A
Sbjct: 82 IGCGSGYQAAVLSQIFRR-VFSIERIESLYIEARLRLKTLGLDNVHVKFADGNKGWEQYA 140
Query: 147 PYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPVGSYHLWQELLEVVKKKSGEIKVR 201
PYD I+ +A A +P+ L++QL+ GG L+ P+ + +++++ K++ ++V+
Sbjct: 141 PYDRILFSACAKNIPQALIDQLEEGGILVAPIQENN--EQVIKRFVKQNNALRVQ 193
>sp|Q9ZKC2|PIMT_HELPJ PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE (PROTEIN-BETA-ASPARTATE
METHYLTRANSFERASE) (PIMT) (PROTEIN L-ISOASPARTYL
METHYLTRANSFERASE) (L-ISOASPARTYL PROTEIN CARBOXYL
METHYLTRANSFERASE) >gi|7451063|pir||D71858
protein-l-isoaspartate o-methyltransferase -
Helicobacter pylori (strain J99)
>gi|4155612|gb|AAD06603.1| (AE001530)
PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE [Helicobacter
pylori J99]
Length = 209
Score = 106 bits (263), Expect = 2e-22
Identities = 62/175 (35%), Positives = 106/175 (60%), Gaps = 3/175 (1%)
Query: 27 EVKEAFLKYPRYMFVEDRYKSYAHIDEPLPIPAGQTVSAPHMVAIMLEIAKLKEGMNVLE 86
+V+EA R +FV +K +A+ L + A Q +S+P VA M + ++ +VLE
Sbjct: 22 KVREAMESIEREVFVPAPFKHFAYTLNALSMQAQQYISSPLTVAKMTQYLEIDHVDSVLE 81
Query: 87 VGTGSGWNAALISYIVKTDVYSIERIPELVEFAKRNLERAGVKNVHVILGDGSKGFPPKA 146
+G GSG+ AA++S I + V+SIERI L A+ L+ G+ NVHV DG+KG+ A
Sbjct: 82 IGCGSGYQAAVLSQIFRR-VFSIERIESLYIEARLRLKTLGLDNVHVKFADGNKGWERYA 140
Query: 147 PYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPVGSYHLWQELLEVVKKKSGEIKVR 201
PYD I+ +A A +P+ L++QL+ GG L+ P+ + +++++ K++ ++V+
Sbjct: 141 PYDRILFSACAKNIPQALIDQLEEGGILVAPIQENN--EQVIKRFVKQNNALRVQ 193
>gb|AAK42721.1| L-isoaspartyl protein carboxyl methyltransferase (pcm) [Sulfolobus
solfataricus]
Length = 236
Score = 102 bits (253), Expect = 3e-21
Identities = 72/212 (33%), Positives = 114/212 (52%), Gaps = 11/212 (5%)
Query: 16 MLEREGIIRSLE---VKEAFLKYPRYMFVEDRYKSYAH----IDEPLPIPAGQTVSAPHM 68
M ++ I+RS++ + AF+K R F+ K YA+ +D+P I T +A +
Sbjct: 1 MSAKDDILRSIKNSKLANAFIKVNREDFLPQLLKKYAYDPNYVDKPFYITPNVTTTALSL 60
Query: 69 VAIMLEIAKLKEGMNVLEVGTGSGWNAALISYIV-KTDVYSIERIPELVEFAKRNLERAG 127
ML+I L E VLE+GTG G+ AL++ +V +V S+E + E+AK N+
Sbjct: 61 GMYMLDILNLGETQKVLEIGTGIGYYTALMAEVVGDNNVISLEIDDTIFEYAK-NILLPK 119
Query: 128 VKNVHVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPVGSYHLWQEL 187
+ +I DGS G+ +APYD II+ A AP VP L +QL+ G +++P+GS +
Sbjct: 120 YPRIKLIKTDGSLGYDKEAPYDRIIIWAAAPTVPCKLYDQLRENGIMVVPIGSEK--AQG 177
Query: 188 LEVVKKKSGEIKVRNHGGVAFVPLIGEYGWRE 219
L + K E K+ G V F+ + G +G+ E
Sbjct: 178 LYRITKIGYEPKIERLGDVIFMKMRGLFGFYE 209
>emb|CAB71208.1| (AL138538) putative O-methyltransferase [Streptomyces coelicolor
A3(2)]
Length = 324
Score = 101 bits (248), Expect = 1e-20
Identities = 60/182 (32%), Positives = 98/182 (52%), Gaps = 31/182 (17%)
Query: 29 KEAFLKYPRYMFV-----------------------EDRYKSYAHIDEPLPIPAGQ---- 61
+EAF K PR++FV +R+ A+ D PL
Sbjct: 35 REAFRKVPRHLFVPYYYVGVRGGYERRWGEDPDPRARERWVRGAYADAPLATRMRDGELL 94
Query: 62 -TVSAPHMVAIMLEIAKLKEGMNVLEVGTGSGWNAALISYIVKTD--VYSIERIPELVEF 118
++S P ++A+ML +++G VLE+G G+G+NAAL+++ + D V +++ PE+ E
Sbjct: 95 SSISQPSLMAMMLVELDVRDGDRVLEIGAGTGYNAALLAHRLGADDLVTTVDLDPEITES 154
Query: 119 AKRNLERAGVKNVHVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPV 178
A+R+L+ AG V+ GDG++G P +APYD I+ T P VP Q +PGGR++ P+
Sbjct: 155 ARRHLDAAGYHPA-VVTGDGARGVPERAPYDRILATCALPSVPRAWPAQCRPGGRILTPL 213
Query: 179 GS 180
+
Sbjct: 214 AT 215
>sp|O08249|PIMT_RHIME PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE (PROTEIN-BETA-ASPARTATE
METHYLTRANSFERASE) (PIMT) (PROTEIN L-ISOASPARTYL
METHYLTRANSFERASE) (L-ISOASPARTYL PROTEIN CARBOXYL
METHYLTRANSFERASE)
Length = 204
Score = 100 bits (247), Expect = 1e-20
Identities = 56/160 (35%), Positives = 89/160 (55%), Gaps = 1/160 (0%)
Query: 19 REGIIRSLEVKEAFLKYPRYMFVEDRYKSYAHIDEPLPIPAGQTVSAPHMVAIMLEIAKL 78
R G I + E+ +A + PR +F +Y+ + +P+ G + M +L L
Sbjct: 6 RSGGIVNHELLKAVEQTPRTLFAPPQYQDEVYSKRLIPLECGSFMEGCDMAVRLLHCLNL 65
Query: 79 KEGMNVLEVGTGSGWNAALISYIVKTDVYSIERIPELVEFAKRNLERAGVKNVHVILGDG 138
K G +LEVGTGSG+ AA++ I + V +I+R LV A++NLE+AG++NV V DG
Sbjct: 66 KPGQRILEVGTGSGFTAAVMGRIAER-VLTIDRYQTLVASAQKNLEKAGLRNVVVRQADG 124
Query: 139 SKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPV 178
S G P + +D I++TA +P + L GG L++P+
Sbjct: 125 SAGVPGEGTFDRILITAAFNSLPRTFSDHLVSGGTLLVPI 164
>gb|AAB88075.1| (U81296) L-isoaspartyl protein carboxyl methyltransferase
[Sinorhizobium meliloti]
Length = 204
Score = 99.8 bits (245), Expect = 2e-20
Identities = 56/160 (35%), Positives = 88/160 (55%), Gaps = 1/160 (0%)
Query: 19 REGIIRSLEVKEAFLKYPRYMFVEDRYKSYAHIDEPLPIPAGQTVSAPHMVAIMLEIAKL 78
R G I + E+ +A + PR F +Y+ + +P+ G + M +L L
Sbjct: 6 RSGGIVNHELLKAVEQTPRTFFAPPQYQDEVYSKRLIPLECGSFMEGCDMAVRLLHCLNL 65
Query: 79 KEGMNVLEVGTGSGWNAALISYIVKTDVYSIERIPELVEFAKRNLERAGVKNVHVILGDG 138
K G +LEVGTGSG+ AA++ I + V +I+R LV A++NLE+AG++NV V DG
Sbjct: 66 KPGQRILEVGTGSGFTAAVMGRIAER-VLTIDRYQTLVASAQKNLEKAGLRNVVVRQADG 124
Query: 139 SKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPV 178
S G P + +D I++TA +P + L GG L++P+
Sbjct: 125 SAGVPGEGTFDRILITAAFNSLPRTFSDHLVSGGTLLVPI 164
>pir||T39119 protein-L-isoaspartate(D-aspartate) O-methyltransferase (EC
2.1.1.77) - fission yeast (Schizosaccharomyces pombe)
>gi|6224599|emb|CAB60018.1| (AL132779) putative
protein-l-isoaspartate o-methyltransferase
[Schizosaccharomyces pombe]
Length = 230
Score = 98.3 bits (241), Expect = 7e-20
Identities = 63/177 (35%), Positives = 99/177 (55%), Gaps = 17/177 (9%)
Query: 50 HIDEPLPIPAGQTVSAPHMVAIMLEIAK--LKEGMNVLEVGTGSGWNAALISYIVKTD-- 105
++D P I G T+SAPHM A L+ + L+ G + L++G+GSG+ A ++ +V +
Sbjct: 46 YMDSPQSIGYGVTISAPHMHATALQELEPVLQPGCSALDIGSGSGYLVAAMARMVAPNGT 105
Query: 106 VYSIERIPELVEFAKRNL-----------ERAGVKNVHVILGDGSKGFPPKAPYDVIIVT 154
V IE IP+LVE +K+NL E K + + +GDG G +D I V
Sbjct: 106 VKGIEHIPQLVETSKKNLLKDINHDEVLMEMYKEKRLQINVGDGRMGTSEDEKFDAIHVG 165
Query: 155 AGAPKVPEPLVEQLKPGGRLIIPVGSYHLWQELLEVVKKKSGEIKVRNHGGVAFVPL 211
A A ++P+ LV+QLK G+++IP+G+Y Q + + K + G+I R V +VPL
Sbjct: 166 ASASELPQKLVDQLKSPGKILIPIGTYS--QNIYLIEKNEQGKISKRTLFPVRYVPL 220
>pir||D81440 protein-L-isoaspartate(D-aspartate) O-methyltransferase (EC
2.1.1.77) Cj0228c [imported] - Campylobacter jejuni
(strain NCTC 11168) >gi|6967706|emb|CAB72697.1|
(AL139074) protein-L-isoaspartate O-methyltransferase
[Campylobacter jejuni]
Length = 209
Score = 96.3 bits (236), Expect = 3e-19
Identities = 64/211 (30%), Positives = 114/211 (53%), Gaps = 8/211 (3%)
Query: 4 MDLYERWKRTVEMLER--EGIIRSLEVKEAFLKYPRYMFVEDRYKSYAHIDEPLPIPAGQ 61
M+ +E+ KR M E + + + E+ AF + PR +F K++A+ + LP+ Q
Sbjct: 1 MNAFEQ-KRCQNMAEEIAQKVFINEELFNAFCQIPREIF--SPLKAHAYRLDALPLANSQ 57
Query: 62 TVSAPHMVAIMLEIAKLKEGMNVLEVGTGSGWNAALISYIVKTDVYSIERIPELVEFAKR 121
+S+P VA M K ++LE+G GSG+ AA++S +++ V++IERI L + A +
Sbjct: 58 WISSPLTVAKMTMALDFKNADSILEIGCGSGYQAAILSKVIRR-VFTIERIENLAKKAAQ 116
Query: 122 NLERAGVKNVHVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPVGSY 181
+ N++V DG G+ APYD I+ +A A ++PE L++QL G L+ P+
Sbjct: 117 TFRELELFNINVKFDDGQNGWKNYAPYDRILFSAYATQIPEILLDQLSDDGILVAPI--L 174
Query: 182 HLWQELLEVVKKKSGEIKVRNHGGVAFVPLI 212
H ++ + ++K ++ FVP++
Sbjct: 175 HNGKQFITRLRKNGTNLQKEILEECLFVPIV 205
>dbj|BAB09395.1| (AB024031) contains similarity to L-isoaspartyl protein carboxyl
methyltransferase~gene_id:K6A12.10 [Arabidopsis
thaliana]
Length = 269
Score = 95.2 bits (233), Expect = 6e-19
Identities = 53/132 (40%), Positives = 82/132 (61%), Gaps = 14/132 (10%)
Query: 90 GSGWNAALISYIVKTD--VYSIERIPELVEFAKRNLERA--------GVKNVHVILGDGS 139
G+G+ + +V + V ++ IPELV+ + +N+E++ G ++HV GDG
Sbjct: 132 GTGYLTGCFALMVGAEGRVVGVDHIPELVDMSIKNIEKSVAASFLKKGSLSLHV--GDGR 189
Query: 140 KGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPVGSYHLWQELLEVVKKKSGEIK 199
KG+ APYD I V A A ++P+PL++QLKPGGR++IP+G+Y +QEL + K + G IK
Sbjct: 190 KGWQEFAPYDAIHVGAAASEIPQPLLDQLKPGGRMVIPLGTY--FQELKVIDKNEDGSIK 247
Query: 200 VRNHGGVAFVPL 211
V V +VPL
Sbjct: 248 VHTETSVRYVPL 259
>sp|Q27873|PIMT_CAEEL PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE (PROTEIN-BETA-ASPARTATE
METHYLTRANSFERASE) (PIMT) (PROTEIN L-ISOASPARTYL
METHYLTRANSFERASE) (L-ISOASPARTYL PROTEIN CARBOXYL
METHYLTRANSFERASE) >gi|7511619|pir||T32150
protein-L-isoaspartate(D-aspartate) O-methyltransferase
(EC 2.1.1.77) pcm-1 - Caenorhabditis elegans
>gi|805080|gb|AAA82166.1| (U09669)
protein-L-isoaspartate (D-aspartate) O-methyltransferase
[Caenorhabditis elegans] >gi|805086|gb|AAB60240.1|
(U15129) protein-L-isoaspartate (D-aspartate)
O-methyltransferase [Caenorhabditis elegans]
>gi|2384785|gb|AAB69887.1| (AF022968) C. elegans
protein-L-isoaspartate O-methyltransferase (PCM-1)
(PID:g805096) [Caenorhabditis elegans]
Length = 225
Score = 94.0 bits (230), Expect = 1e-18
Identities = 64/169 (37%), Positives = 96/169 (55%), Gaps = 10/169 (5%)
Query: 52 DEPLPIPAGQTVSAPHMVAIMLEIAK--LKEGMNVLEVGTGSGWNAALISYIVKTD--VY 107
D P I TVSAPHM A L+ + L G L+VG+GSG+ ++ +V + V
Sbjct: 48 DAPQRIGYNATVSAPHMHAAALDYLQNHLVAGAKALDVGSGSGYLTVCMAMMVGRNGTVV 107
Query: 108 SIERIPELVEFAKRNL-----ERAGVKNVHVILGDGSKGFPPKAPYDVIIVTAGAPKVPE 162
IE +P+LVE +++N+ E+ NV +I GDG +GF KAPY+ I V A + VP+
Sbjct: 108 GIEHMPQLVELSEKNIRKHHSEQLERGNVIIIEGDGRQGFAEKAPYNAIHVGAASKGVPK 167
Query: 163 PLVEQLKPGGRLIIPVGSYHLWQELLEVVKKKSGEIKVRNHGGVAFVPL 211
L +QL GGR++IPV Q ++ + K +G+I+ + V +VPL
Sbjct: 168 ALTDQLAEGGRMMIPVEQVDGNQVFMQ-IDKINGKIEQKIVEHVIYVPL 215
>pir||C81031 protein-L-isoaspartate O-methyltransferase NMB1885 [imported] -
Neisseria meningitidis (group B strain MD58)
>gi|7227144|gb|AAF42219.1| (AE002538)
protein-L-isoaspartate O-methyltransferase [Neisseria
meningitidis MC58]
Length = 218
Score = 89.3 bits (218), Expect = 3e-17
Identities = 59/185 (31%), Positives = 93/185 (49%), Gaps = 1/185 (0%)
Query: 4 MDLYERWKRTVEMLEREGIIRSLEVKEAFLKYPRYMFVEDRYKSYAHIDEPLPIPAGQTV 63
MD + VE R + +V +A + PR +FV++ + A+ D LP+ G +
Sbjct: 1 MDFEKARFNMVEQQIRPWDVLDFDVLDALAEIPRELFVDEDLQGLAYADMALPLANGHKM 60
Query: 64 SAPHMVAIMLEIAKLKEGMNVLEVGTGSGWNAALISYIVKTDVYSIERIPELVEFAKRNL 123
P +VA + + KL + VLE+GTGSG+ AL++ + V S + E AK L
Sbjct: 61 LEPKVVARLAQGLKLTKNDTVLEIGTGSGYATALLAKLAGR-VVSDDIDVEQQNRAKAVL 119
Query: 124 ERAGVKNVHVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPVGSYHL 183
+ G+ N+ + +G AP+D + V VPE L EQLK GGR+++ VG +
Sbjct: 120 DGLGLDNIDYVQNNGLTELSAGAPFDAVYVGGAVNLVPEVLKEQLKDGGRMVVIVGRKPV 179
Query: 184 WQELL 188
+ LL
Sbjct: 180 QRALL 184
>pir||A81976 probable protein-L-isoaspartate(D-aspartate) O-methyltransferase
(EC 2.1.1.77) NMA0572 [imported] - Neisseria
meningitidis (group A strain Z2491)
>gi|7379308|emb|CAB83863.1| (AL162753) putative
protein-L-isoaspartate O-methyltransferase [Neisseria
meningitidis Z2491]
Length = 218
Score = 89.3 bits (218), Expect = 3e-17
Identities = 63/197 (31%), Positives = 96/197 (47%), Gaps = 1/197 (0%)
Query: 4 MDLYERWKRTVEMLEREGIIRSLEVKEAFLKYPRYMFVEDRYKSYAHIDEPLPIPAGQTV 63
MD + VE R + +V +A + PR +FV++ + A+ D LP+ G +
Sbjct: 1 MDFEKARFNMVEQQIRPWDVLDFDVLDALAEIPRELFVDEDLQGLAYADMALPLANGHKM 60
Query: 64 SAPHMVAIMLEIAKLKEGMNVLEVGTGSGWNAALISYIVKTDVYSIERIPELVEFAKRNL 123
P +VA + + KL + VLE+GTGSG+ AL++ + V S + E AK L
Sbjct: 61 LEPKVVARLAQGLKLTKNDTVLEIGTGSGYATALLAKLA-GKVVSDDLDAEQQNRAKAVL 119
Query: 124 ERAGVKNVHVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPVGSYHL 183
+ G+ N+ + +G AP+D + V VPE L EQLK GGR+ + VG +
Sbjct: 120 DGLGLDNIDYVQNNGLTELSAGAPFDAVYVGGAVNLVPEVLKEQLKDGGRMAVIVGRKPV 179
Query: 184 WQELLEVVKKKSGEIKV 200
+ LL K E KV
Sbjct: 180 QRALLITRKGDVFEEKV 196
>gb|AAG18721.1| (AE004977) L-isoaspartyl protein carboxyl methyltransferase; PimT1
[Halobacterium sp. NRC-1]
Length = 245
Score = 86.2 bits (210), Expect = 3e-16
Identities = 63/178 (35%), Positives = 98/178 (54%), Gaps = 10/178 (5%)
Query: 36 PRYMFVEDRYKSYAHIDEPLPIPAGQTVSAPHMVAIMLEIAKLKEGMNVLEVGTGSGWNA 95
PR+ FV+ +++Y D+ G V AP VA ++ + + G +VL VG G G+
Sbjct: 35 PRHEFVDAGHRAYT--DQAFE-HRGTRVLAPSTVARLVGALEPRAGDDVLVVGAGVGYTV 91
Query: 96 ALISYIV-KTDVYSIERIPELVEFAKRNLERAGVKNVHVILGDGSKGFPPKAPYDVIIVT 154
A+++ I T V++++ ++V A+ NL AG ++V V DG++G AP+D ++V
Sbjct: 92 AVVAEIAGPTHVHAVDIDRQVVYDARGNLADAGYEDVLVDCRDGAEGLAEYAPFDRVLVE 151
Query: 155 AGAPKVPEPLVEQLKPGGRLIIPVGSYHLWQELLEVVKKKSGEIKVRNHGGVAFVPLI 212
AGA VP+ L QL GRL+ P G Q L+ V + GE V HG V+F PL+
Sbjct: 152 AGAASVPDALARQLAADGRLVFPEGVGD--QRLVSV---RDGE-TVGVHGPVSFAPLL 203
>gb|AAF70310.1|AF260132_1 (AF260132) putative protein-L-isoaspartate O-methyltransferase
[Pseudomonas putida]
Length = 107
Score = 81.9 bits (199), Expect = 6e-15
Identities = 45/99 (45%), Positives = 65/99 (65%), Gaps = 1/99 (1%)
Query: 114 ELVEFAKRNLERAGVKNVHVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGR 173
+L + AK L ++NV GDG +G+P APY+ IIVTA AP+VP+ L++QL PGGR
Sbjct: 5 DLHDRAKERLVELNLRNVVFRWGDGCEGWPALAPYNGIIVTAVAPEVPQALLDQLAPGGR 64
Query: 174 LIIPVGSYHLWQELLEVVKKKSGEIKVRNHGGVAFVPLI 212
++IPVG Q+L+ +V+++ G R G V FVPL+
Sbjct: 65 MVIPVGPAGEAQQLMLIVREEHG-FSRRVLGAVRFVPLL 102
>gb|AAA90933.1| (M93009) L-isoaspartyl/D-aspartyl protein carboxyl
methyltransferase [Homo sapiens]
Length = 108
Score = 79.2 bits (192), Expect = 4e-14
Identities = 41/81 (50%), Positives = 54/81 (66%)
Query: 131 VHVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPVGSYHLWQELLEV 190
V +++GDG G+ +APYD I V A AP VP+ L++QLKPGGRLI+PVG Q L +
Sbjct: 17 VQLVVGDGRMGYAEEAPYDAIHVGAAAPVVPQALIDQLKPGGRLILPVGPAGGNQMLEQY 76
Query: 191 VKKKSGEIKVRNHGGVAFVPL 211
K + G IK+R GV +VPL
Sbjct: 77 DKLQDGSIKMRPLMGVIYVPL 97
>gb|AAF80359.1|AF157831_1 (AF157831) L-isoaspartyl protein carboxyl methyltransferase homolog
[Bartonella bacilliformis]
Length = 219
Score = 78.4 bits (190), Expect = 6e-14
Identities = 50/165 (30%), Positives = 85/165 (51%), Gaps = 1/165 (0%)
Query: 31 AFLKYPRYMFVEDRYKSYAHIDEPLPIPAGQTVSAPHMVAIMLEIAKLKEGMNVLEVGTG 90
AF K PR FV + + A+ ++ +PI G+ + ++L L++ VLE+GTG
Sbjct: 33 AFEKIPRQYFVSSPWLNSAYDNKVIPIECGEYIERLEEQLLILFALSLRKKHRVLEIGTG 92
Query: 91 SGWNAALISYIVKTDVYSIERIPELVEFAKRNLERAGVKNVHVILGDGSKGFPPKAPYDV 150
SG+ +ALI+Y+ V +++R LV+ A++ + G++N+ V DGS+G +D
Sbjct: 93 SGFCSALIAYL-SDRVVTVDRYKTLVDLARQKFQTLGIENIVVHQIDGSRGVTGFGLFDR 151
Query: 151 IIVTAGAPKVPEPLVEQLKPGGRLIIPVGSYHLWQELLEVVKKKS 195
I++ PE +E L G LI +G Q + +K S
Sbjct: 152 ILIWPSRSDEPEEFLELLTGNGILIQAIGPDEGVQMVTRYIKNGS 196
>sp|P45683|PIMT_PSEAE PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE (PROTEIN-BETA-ASPARTATE
METHYLTRANSFERASE) (PIMT) (PROTEIN L-ISOASPARTYL
METHYLTRANSFERASE) (L-ISOASPARTYL PROTEIN CARBOXYL
METHYLTRANSFERASE) >gi|2120644|pir||S55062 protein
L-aspartyl carboxy methyltransferase - Pseudomonas
aeruginosa (fragment) >gi|4433349|dbj|BAA05129.1|
(D26134) protein L-aspartyl carboxy methyltransferase
[Pseudomonas aeruginosa]
Length = 104
Score = 71.8 bits (173), Expect = 6e-12
Identities = 43/101 (42%), Positives = 62/101 (60%), Gaps = 2/101 (1%)
Query: 112 IPELVEFAKRNLERAGVKNVHVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPG 171
I L + AK L ++NV GDG +G+ APY+ IIVTA A +VP+ L++QL PG
Sbjct: 1 IQALQDKAKERLAELNLRNVVFRWGDGWEGWSALAPYNGIIVTAAATEVPQSLLDQLAPG 60
Query: 172 GRLIIPVGSYHLWQELLEVVKKKSGEIKVRNHGGVAFVPLI 212
GRL+IPVG + Q+L+ +V+ + G + V FVPL+
Sbjct: 61 GRLVIPVGGGEV-QQLMLIVRTEDG-FSRQVLDSVRFVPLL 99
>pir||H82539 protein-L-isoaspartate O-methyltransferase XF2585 [imported] -
Xylella fastidiosa (strain 9a5c)
>gi|9107802|gb|AAF85382.1|AE004065_7 (AE004065)
protein-L-isoaspartate O-methyltransferase [Xylella
fastidiosa]
Length = 218
Score = 69.1 bits (166), Expect = 4e-11
Identities = 50/179 (27%), Positives = 86/179 (47%), Gaps = 3/179 (1%)
Query: 11 KRTVEMLEREGIIRSLEVKEAFLKYPRYMFVEDRYKSYAHIDEPLPIPAGQTVSAPHMVA 70
++ VE R + L V + PR FV + Y++ A+ D +P+ GQT+ P +
Sbjct: 10 EKMVEQQIRPWDVVDLHVLDVLAHIPREAFVPEPYRTLAYADLEIPLHGGQTMMKPVIEG 69
Query: 71 IMLEIAKLKEGMNVLEVGTGSGWNAALISYIVKTDVYSIERIPELVEFAKRNLERAGV-K 129
+L+ L +VLE+GTGSG+ A ++ + ++ S+E L A +L+ G+
Sbjct: 70 RLLQALMLSPEEDVLEIGTGSGFLTACLASL-GHEIVSLEINSALGASAHTHLDTIGLGS 128
Query: 130 NVHVILGDGSKGFPPKAPYDVIIVTAGAPKVPEPLVEQLKPGGRLIIPVGSYHLWQELL 188
NVH+ D + P+ + VI +T +P ++ L P GR+ G Q +L
Sbjct: 129 NVHIEQADAFT-WQPERQFSVICLTGAVNTLPLQFLQWLHPNGRMFAIHGHSPAMQAVL 186
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.319 0.140 0.414
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 88109511
Number of Sequences: 2977
Number of extensions: 4040131
Number of successful extensions: 10595
Number of sequences better than 1.0e-10: 51
Number of HSP's better than 0.0 without gapping: 33
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 10477
Number of HSP's gapped (non-prelim): 51
length of query: 219
length of database: 189,106,746
effective HSP length: 53
effective length of query: 166
effective length of database: 157,386,935
effective search space: 26126231210
effective search space used: 26126231210
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 163 (67.9 bits)