BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB1245 (alaS) DE:alanyl-tRNA synthetase (alaS)
(914 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||B75017 alanyl-tRNA synthetase (alas) PAB1245 - Pyrococcus a... 1857 0.0
sp|O58035|SYA_PYRHO ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 1710 0.0
sp|Q57984|SYA_METJA ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 901 0.0
sp|O27718|SYA_METTH ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 873 0.0
gi|11499836 alanyl-tRNA synthetase (alaS) [Archaeoglobus fulgidu... 841 0.0
gb|AAG20397.1| (AE005112) alanyl-tRNA synthetase; AlaS [Halobact... 756 0.0
gb|AAK40671.1| Alanyl-tRNA synthetase (alaS) [Sulfolobus solfata... 679 0.0
sp|Q9Y9X3|SYA_AERPE ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 671 0.0
emb|CAC11978.1| (AL445065) alanyl-tRNA synthetase related protei... 659 0.0
gb|AAG23137.1|AF245445_1 (AF245445) alanyl-tRNA synthetase [Giar... 449 e-125
gb|AAF05594.1|AF188719_1 (AF188719) alanyl-tRNA synthetase [Giar... 448 e-124
sp|O67323|SYA_AQUAE ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 340 5e-92
sp|Q9XDM3|SYA_AQUPY ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 332 9e-90
dbj|BAB04986.1| (AP001511) alanyl-tRNA synthetase [Bacillus halo... 313 6e-84
sp|O34526|SYA_BACSU ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 312 1e-83
sp|Q9X1B6|SYA_THEMA ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 300 4e-80
sp|P74423|SYA_SYNY3 ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 293 8e-78
sp|Q56273|SYA_THIFE ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 282 9e-75
sp|P74941|SYA_THETH ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 280 3e-74
sp|P27866|SYA_RHIME ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 276 7e-73
sp|Q9ZCA4|SYA_RICPR ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 273 4e-72
dbj|BAB10601.1| (AB005243) alanyl-tRNA synthetase [Arabidopsis t... 271 2e-71
pir||C81804 alanine--tRNA ligase (EC 6.1.1.7) NMA1788 [imported]... 267 4e-70
pir||F81063 alanyl-tRNA synthetase NMB1595 [imported] - Neisseri... 266 8e-70
pir||H83533 alanyl-tRNA synthetase PA0903 [imported] - Pseudomon... 264 4e-69
gb|AAD53924.1|AF179611_8 (AF179611) alanyl-tRNA synthetase [Zymo... 263 9e-69
sp|P70865|SYA_BARBA ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 260 6e-68
sp|Q9ZJY5|SYA_HELPJ ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 258 2e-67
pir||F75289 alanyl-tRNA synthetase - Deinococcus radiodurans (st... 255 2e-66
emb|CAB93381.1| (AL357523) alanine tRNA synthetase [Streptomyces... 254 4e-66
sp|P56452|SYA_HELPY ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 253 6e-66
sp|O07438|SYA_MYCTU ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 253 6e-66
pir||C81396 alanine--tRNA ligase (EC 6.1.1.7) Cj0506 [imported] ... 242 2e-62
sp|P57483|SYA_BUCAI ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 237 5e-61
pir||G82310 alanyl-tRNA synthetase VC0545 [imported] - Vibrio ch... 235 1e-60
sp|P43815|SYA_HAEIN ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 234 3e-60
pir||C82844 alanyl-tRNA synthetase XF0124 [imported] - Xylella f... 231 2e-59
pir||H81739 alanyl-tRNA synthetase TC0125 [imported] - Chlamydia... 231 2e-59
gb|AAC49007.1| (U18672) cytoplasmic alanyl-tRNA synthetase [Sacc... 230 6e-59
gi|6324911 Cytoplasmic alanyl-tRNA synthetase gene; Ala1p [Sacch... 230 6e-59
sp|P00957|SYA_ECOLI ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 229 8e-59
gb|AAA03208.1| (J01581) alanyl-tRNA synthetase [Escherichia coli] 229 1e-58
gb|AAG23689.1|AF297520_1 (AF297520) alanyl-tRNA synthase [Haemop... 219 2e-55
pir||E71476 alanine--tRNA ligase (EC 6.1.1.7) - Chlamydia tracho... 215 1e-54
sp|O84754|SYA_CHLTR ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 215 2e-54
sp|Q9Z714|SYA_CHLPN ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 213 9e-54
sp|O13914|SYAC_SCHPO PROBABLE ALANYL-TRNA SYNTHETASE, CYTOPLASMI... 210 4e-53
sp|P21894|SYA_BOMMO ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 202 1e-50
sp|P35029|SYA_SULAC ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 196 7e-49
gb|AAD50044.1|AC007980_9 (AC007980) 78688 [Arabidopsis thaliana] 196 1e-48
gb|AAF05592.1|AF188717_1 (AF188717) alanyl-tRNA synthetase [Dict... 194 4e-48
pir||S32671 alanine--tRNA ligase (EC 6.1.1.7) - Arabidopsis thal... 193 8e-48
sp|P36428|SYA_ARATH ALANYL-TRNA SYNTHETASE, MITOCHONDRIAL PRECUR... 193 8e-48
emb|CAA80381.1| (Z22673) cytosolic tRNA-Ala synthetase [Arabidop... 193 8e-48
gb|AAF52657.1| (AE003621) Aats-ala gene product [Drosophila mela... 190 4e-47
pir||T29466 hypothetical protein F28H1.3 - Caenorhabditis elegan... 189 1e-46
gi|4501841 alanyl-tRNA synthetase [Homo sapiens] >gi|1351144|sp|... 186 1e-45
gb|AAF05593.1|AF188718_1 (AF188718) alanyl-tRNA synthetase [Dros... 185 2e-45
sp|P96041|SYA_SULSO ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 182 2e-44
pir||D82899 alanyl-tRNA synthetase UU369 [imported] - Ureaplasma... 181 3e-44
gi|11431793 alanyl-tRNA synthetase [Homo sapiens] 171 3e-41
pir||A71213 alanine--tRNA ligase truncated homolog PH1969 - Pyro... 170 5e-41
dbj|BAA86584.1| (AB033096) KIAA1270 protein [Homo sapiens] 166 1e-39
pir||G75027 alanyl-tRNA synthetase related protein PAB1190 - Pyr... 157 7e-37
emb|CAC11271.1| (AL445063) alanyl-tRNA synthetase related protei... 151 3e-35
sp|P47534|SYA_MYCGE ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 145 2e-33
sp|P75368|SYA_MYCPN ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 144 4e-33
gb|AAF05590.1|AF188715_1 (AF188715) alanyl-tRNA synthetase [Caen... 137 6e-31
pir||C75511 alanyl-tRNA synthetase-related protein - Deinococcus... 136 8e-31
pir||B71231 alanine--tRNA ligase truncated homolog PH0108 - Pyro... 135 2e-30
pir||A75198 alanine--tRNA ligase truncated homolog PAB0066 - Pyr... 133 1e-29
dbj|BAB06653.1| (AP001517) unknown conserved protein in others [... 131 3e-29
gb|AAK40776.1| Alanyl-tRNA synthetase truncated homolog (alaS-li... 129 1e-28
pir||T26086 hypothetical protein W02B12.6 - Caenorhabditis elega... 127 7e-28
emb|CAA83717.1| (Z33042) Ala-tRNA synthetase [Mycoplasma caprico... 123 1e-26
pir||S77844 alanine--tRNA ligase (EC 6.1.1.7) - Mycoplasma capri... 123 1e-26
sp|O83980|SYA_TREPA ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 121 4e-26
pir||G72685 probable alanyl-tRNA synthetase APE0903 - Aeropyrum ... 119 1e-25
pir||E72216 alanine--tRNA ligase truncated homolog TM1726 - Ther... 117 5e-25
sp|O51238|SYA_BORBU ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 106 9e-22
gb|AAF45874.1| (AE003427) CG10802 gene product [Drosophila melan... 104 3e-21
pir||A83382 hypothetical protein PA2106 [imported] - Pseudomonas... 102 2e-20
sp|Q56648|SYA_VIBCH ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE... 97 1e-18
pir||B71172 alanine--tRNA ligase truncated homolog PH0574 - Pyro... 96 2e-18
gb|AAF05591.1|AF188716_1 (AF188716) alanyl-tRNA synthetase [Dros... 90 8e-17
gi|6324288 Ynl040wp [Saccharomyces cerevisiae] >gi|1730724|sp|P5... 90 8e-17
pir||A75053 alanine--tRNA ligase truncated homolog PAB1440 - Pyr... 90 1e-16
emb|CAC00447.1| (AL160371) possible hypothetical 51.0 Kd protein... 90 1e-16
gb|AAF50804.1| (AE003567) Aats-ala-m gene product [Drosophila me... 89 3e-16
pir||T03808 alanine--tRNA ligase (EC 6.1.1.7) - Mycoplasma hyopn... 78 3e-13
gb|AAK41508.1| Alanyl-tRNA synthetase truncated homolog (alaS-li... 78 4e-13
emb|CAC11640.1| (AL445064) conserved hypothetical protein [Therm... 72 2e-11
>pir||B75017 alanyl-tRNA synthetase (alas) PAB1245 - Pyrococcus abyssi (strain
Orsay) >gi|5459090|emb|CAB50576.1| (AJ248288)
alanyl-tRNA synthetase (alaS) [Pyrococcus abyssi]
Length = 914
Score = 1857 bits (4758), Expect = 0.0
Identities = 914/914 (100%), Positives = 914/914 (100%)
Query: 1 MEFIMKTRMFEEEGWIRKKCKVCGKPFWTLDPDRETCGDPPCDEYQFIGKPGIPKKYTLD 60
MEFIMKTRMFEEEGWIRKKCKVCGKPFWTLDPDRETCGDPPCDEYQFIGKPGIPKKYTLD
Sbjct: 1 MEFIMKTRMFEEEGWIRKKCKVCGKPFWTLDPDRETCGDPPCDEYQFIGKPGIPKKYTLD 60
Query: 61 EMREKFLKFFEKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPANPL 120
EMREKFLKFFEKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPANPL
Sbjct: 61 EMREKFLKFFEKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPANPL 120
Query: 121 VISQPSIRFTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFEFFTKELKM 180
VISQPSIRFTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFEFFTKELKM
Sbjct: 121 VISQPSIRFTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFEFFTKELKM 180
Query: 181 KPEDITFKENPWAGGGNAGPAFEVLYRGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYV 240
KPEDITFKENPWAGGGNAGPAFEVLYRGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYV
Sbjct: 181 KPEDITFKENPWAGGGNAGPAFEVLYRGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYV 240
Query: 241 PMETKVVDTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSRLAG 300
PMETKVVDTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSRLAG
Sbjct: 241 PMETKVVDTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSRLAG 300
Query: 301 MFDIEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSN 360
MFDIEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSN
Sbjct: 301 MFDIEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSN 360
Query: 361 VKAGYLARLLIRKSIRHLKELGLEVPLSEIVALHIKELHKTFPEFKEMEDVILEIIDLEE 420
VKAGYLARLLIRKSIRHLKELGLEVPLSEIVALHIKELHKTFPEFKEMEDVILEIIDLEE
Sbjct: 361 VKAGYLARLLIRKSIRHLKELGLEVPLSEIVALHIKELHKTFPEFKEMEDVILEIIDLEE 420
Query: 421 KKYSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKVH 480
KKYSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKVH
Sbjct: 421 KKYSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKVH 480
Query: 481 VPDNFYSIVAKEAEKEKEEKEEEVVDFELVKDLPETRTLYYEDPFMKEFEARVLRVIGDW 540
VPDNFYSIVAKEAEKEKEEKEEEVVDFELVKDLPETRTLYYEDPFMKEFEARVLRVIGDW
Sbjct: 481 VPDNFYSIVAKEAEKEKEEKEEEVVDFELVKDLPETRTLYYEDPFMKEFEARVLRVIGDW 540
Query: 541 IVLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTNVQKVGKVIVHKVENPGLFKEGMEVRGR 600
IVLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTNVQKVGKVIVHKVENPGLFKEGMEVRGR
Sbjct: 541 IVLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTNVQKVGKVIVHKVENPGLFKEGMEVRGR 600
Query: 601 IDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTTDWARLDISHYKRISDEELRE 660
IDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTTDWARLDISHYKRISDEELRE
Sbjct: 601 IDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTTDWARLDISHYKRISDEELRE 660
Query: 661 IERLANRIVMEDRKVTWEWLPRTEAEQRYGFRLYQGGVVPGRVIRVVKIEDWDVQACGGT 720
IERLANRIVMEDRKVTWEWLPRTEAEQRYGFRLYQGGVVPGRVIRVVKIEDWDVQACGGT
Sbjct: 661 IERLANRIVMEDRKVTWEWLPRTEAEQRYGFRLYQGGVVPGRVIRVVKIEDWDVQACGGT 720
Query: 721 HLPSTGLVGPIKILRTERIQDGVERIIFACGEAAIKEWQKEREILKKASQVLRVPPEKLP 780
HLPSTGLVGPIKILRTERIQDGVERIIFACGEAAIKEWQKEREILKKASQVLRVPPEKLP
Sbjct: 721 HLPSTGLVGPIKILRTERIQDGVERIIFACGEAAIKEWQKEREILKKASQVLRVPPEKLP 780
Query: 781 ETAERFFNEWKEARKEVEKLKKELAKLLVYELEAKVQKVKEYEFIGEIVEGSMDDLREAV 840
ETAERFFNEWKEARKEVEKLKKELAKLLVYELEAKVQKVKEYEFIGEIVEGSMDDLREAV
Sbjct: 781 ETAERFFNEWKEARKEVEKLKKELAKLLVYELEAKVQKVKEYEFIGEIVEGSMDDLREAV 840
Query: 841 ERLKKPNRIVVLVSKEGYFAISVGDNVNLNANDLAKKLTSIAGGGGGGRKDVAQGRIKDV 900
ERLKKPNRIVVLVSKEGYFAISVGDNVNLNANDLAKKLTSIAGGGGGGRKDVAQGRIKDV
Sbjct: 841 ERLKKPNRIVVLVSKEGYFAISVGDNVNLNANDLAKKLTSIAGGGGGGRKDVAQGRIKDV 900
Query: 901 SKAKEAIESIVKLL 914
SKAKEAIESIVKLL
Sbjct: 901 SKAKEAIESIVKLL 914
>sp|O58035|SYA_PYRHO ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|7437626|pir||C71455 alanine--tRNA ligase (EC
6.1.1.7) - Pyrococcus horikoshii
>gi|3256687|dbj|BAA29370.1| (AP000001) 915aa long
hypothetical alanyl-tRNA synthetase [Pyrococcus
horikoshii]
Length = 915
Score = 1710 bits (4381), Expect = 0.0
Identities = 808/910 (88%), Positives = 882/910 (96%)
Query: 1 MEFIMKTRMFEEEGWIRKKCKVCGKPFWTLDPDRETCGDPPCDEYQFIGKPGIPKKYTLD 60
MEFIMKTRMFEEEGWIRKKCKVCGKPFWTLDPDRETCGDPPCDEYQFIGKPGIP+KYTLD
Sbjct: 1 MEFIMKTRMFEEEGWIRKKCKVCGKPFWTLDPDRETCGDPPCDEYQFIGKPGIPRKYTLD 60
Query: 61 EMREKFLKFFEKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPANPL 120
EMREKFL+FFEKHE+YPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPANPL
Sbjct: 61 EMREKFLRFFEKHEIYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPANPL 120
Query: 121 VISQPSIRFTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFEFFTKELKM 180
VISQPSIRFTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYW+DETVELAFEFFTKELKM
Sbjct: 121 VISQPSIRFTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWMDETVELAFEFFTKELKM 180
Query: 181 KPEDITFKENPWAGGGNAGPAFEVLYRGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYV 240
KPEDITFKENPWAGGGNAGPAFEVLYRGLEVATLVFMQYKKAPENAP+DQVV+IKG++Y+
Sbjct: 181 KPEDITFKENPWAGGGNAGPAFEVLYRGLEVATLVFMQYKKAPENAPQDQVVVIKGEKYI 240
Query: 241 PMETKVVDTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSRLAG 300
PMETKVVDTGYGLERLVWMSQGTPTAYDAVLGYVVEPLK+MAG+EKIDE+ILMENSRLAG
Sbjct: 241 PMETKVVDTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKKMAGIEKIDEKILMENSRLAG 300
Query: 301 MFDIEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSN 360
MFDIED+GDL+ LR++VA++VGI+VEELEKAIRPYELIYAIADHTKALTFMLADGV+PSN
Sbjct: 301 MFDIEDLGDLRYLREQVAKRVGITVEELEKAIRPYELIYAIADHTKALTFMLADGVVPSN 360
Query: 361 VKAGYLARLLIRKSIRHLKELGLEVPLSEIVALHIKELHKTFPEFKEMEDVILEIIDLEE 420
VKAGYLARLLIRKSIRHL+ELGLEVPLSEIVALHIKELHKTFPEFKEMED+ILE+I+LEE
Sbjct: 361 VKAGYLARLLIRKSIRHLRELGLEVPLSEIVALHIKELHKTFPEFKEMEDIILEMIELEE 420
Query: 421 KKYSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKVH 480
KKY+ETL+RGSDLVRREIAKLKKKG+ EIP+EKL+TFYESHGLTPE+VKEIAEKEG+KV+
Sbjct: 421 KKYAETLRRGSDLVRREIAKLKKKGIKEIPVEKLVTFYESHGLTPEIVKEIAEKEGVKVN 480
Query: 481 VPDNFYSIVAKEAEKEKEEKEEEVVDFELVKDLPETRTLYYEDPFMKEFEARVLRVIGDW 540
+PDNFYS+VAKEAE+ KEEK EE+VDFEL+KDLP+TR LYYEDPFMKEF+A+VLRVI DW
Sbjct: 481 IPDNFYSMVAKEAERTKEEKGEELVDFELLKDLPDTRRLYYEDPFMKEFDAKVLRVIKDW 540
Query: 541 IVLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTNVQKVGKVIVHKVENPGLFKEGMEVRGR 600
++LD TAFYPEGGGQPYDTGVL VNG EVKVTNVQKVGKVI+HKVE+PG FKEGM V G+
Sbjct: 541 VILDATAFYPEGGGQPYDTGVLIVNGREVKVTNVQKVGKVIIHKVEDPGAFKEGMIVHGK 600
Query: 601 IDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTTDWARLDISHYKRISDEELRE 660
IDW RRIQHMRHHTGTHVLMGALVRVLG+HVWQAGSQLTTDWARLDISHYKRIS+EEL+E
Sbjct: 601 IDWKRRIQHMRHHTGTHVLMGALVRVLGRHVWQAGSQLTTDWARLDISHYKRISEEELKE 660
Query: 661 IERLANRIVMEDRKVTWEWLPRTEAEQRYGFRLYQGGVVPGRVIRVVKIEDWDVQACGGT 720
IE LANRIVMEDRKVTWEWLPRT AEQ+YGFRLYQGGVVPGR IRVVKIEDWDVQACGGT
Sbjct: 661 IEMLANRIVMEDRKVTWEWLPRTTAEQKYGFRLYQGGVVPGREIRVVKIEDWDVQACGGT 720
Query: 721 HLPSTGLVGPIKILRTERIQDGVERIIFACGEAAIKEWQKEREILKKASQVLRVPPEKLP 780
HLPSTGLVGPIKILRTERIQDGVERIIFACGEAAI+EWQKER++LKKAS VLRVPPEKLP
Sbjct: 721 HLPSTGLVGPIKILRTERIQDGVERIIFACGEAAIREWQKERDLLKKASNVLRVPPEKLP 780
Query: 781 ETAERFFNEWKEARKEVEKLKKELAKLLVYELEAKVQKVKEYEFIGEIVEGSMDDLREAV 840
ETAERFFNEWKEARKEV+KLKKELA+LLVYELE+K+QK+ EFIGE+VEGSM+DLRE V
Sbjct: 781 ETAERFFNEWKEARKEVDKLKKELARLLVYELESKMQKIGSIEFIGEVVEGSMEDLRELV 840
Query: 841 ERLKKPNRIVVLVSKEGYFAISVGDNVNLNANDLAKKLTSIAGGGGGGRKDVAQGRIKDV 900
E+LKKP R+VVL+S++GYFA+SVG V + AN+LAKK+T IAGGGGGGR+D+AQG++KD+
Sbjct: 841 EKLKKPKRVVVLISRDGYFAVSVGSEVGVEANELAKKITLIAGGGGGGRRDIAQGKVKDI 900
Query: 901 SKAKEAIESI 910
SKAK+ IESI
Sbjct: 901 SKAKDVIESI 910
>sp|Q57984|SYA_METJA ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|2118343|pir||D64370 alanine--tRNA ligase (EC
6.1.1.7) - Methanococcus jannaschii
>gi|1591270|gb|AAB98556.1| (U67505) alanyl-tRNA
synthetase (alaS) [Methanococcus jannaschii]
Length = 892
Score = 901 bits (2302), Expect = 0.0
Identities = 456/920 (49%), Positives = 628/920 (67%), Gaps = 38/920 (4%)
Query: 1 MEFIMKTRMFEEEGWIRKKCKVCGKPFWTLDPDRETCGDPPCDEYQFIGKPGIPKKYTLD 60
M+ K ++F+E G++RKKCK CG+ FWTLD +RETCGD PCD Y FIGKP K YT
Sbjct: 1 MKHNYKVKLFDELGFVRKKCKKCGQWFWTLDEERETCGDAPCDIYSFIGKPITKKPYTYK 60
Query: 61 EMREKFLKFFEKHEVYPHGRVKRYPVLPR-WRDDVLLVGASIMDFQPWVISGEADPPANP 119
EM ++F+ FF++H H +KR PV R WRDD+LL ASI FQPW+ G P ANP
Sbjct: 61 EMVKEFINFFKEHG---HEPIKRAPVTARRWRDDILLTIASIAVFQPWITKGIVKPKANP 117
Query: 120 LVISQPSIRFTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFEFFTKELK 179
LVI+QP IR DIDNVG TGRH T F M HHAFN YW DETVEL F FF K+L
Sbjct: 118 LVIAQPCIRLNDIDNVGRTGRHLTCFTMGGHHAFNREDDFKYWQDETVELCFNFF-KKLG 176
Query: 180 MKPEDITFKENPWAGGGNAGPAFEVLYRGLEVATLVFMQYKKAPENAPEDQVVIIKGDRY 239
+ + ITF E+ W GGGNAGP +EV+ G+E+ATLVFMQY+K GD Y
Sbjct: 177 IDEKSITFIESWWEGGGNAGPCYEVITHGVELATLVFMQYEKV-------------GDNY 223
Query: 240 VPMETKVVDTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSRLA 299
+ K+VDTGYG+ER VW S G PT YDA+ +V LK AGV+ ID+ IL + + +A
Sbjct: 224 KEIPLKIVDTGYGIERFVWASTGEPTIYDAIFKNIVNKLKEDAGVKDIDKEILAKITEVA 283
Query: 300 GMFDIEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPS 359
G+ D++D+GDL+ LR++VA KV I VEEL+K I PYE IYAI DHT+AL FML DG++PS
Sbjct: 284 GLMDVKDVGDLRKLREEVANKVNIPVEELDKLISPYEDIYAIVDHTRALAFMLGDGIVPS 343
Query: 360 NVKAGYLARLLIRKSIRHLKELGLEVPLSEIVALHIKELHKTFPEFKEMEDVILEIIDLE 419
NVK GYL R+LIRK++RH+ L L P++EIVA+ + EL +PE +MED I+EI+++E
Sbjct: 344 NVKDGYLVRMLIRKTLRHMDRLNLSTPITEIVAMQLNELKDLYPELLDMEDYIMEILEIE 403
Query: 420 EKKYSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKV 479
KY +T++RG +V R + K EI LE LI Y+SHGL PE+VK++A+ G V
Sbjct: 404 TNKYRQTIERGKGIVERLL-----KSKKEIDLENLIELYDSHGLPPEIVKDVAKSLGKDV 458
Query: 480 HVPDNFYSIVAKEAEKEKEEKEEEVVDFELVKDLPETRTLYYEDPFMKEFEARVLRVIGD 539
+PDNFY+IVA+ E +KE KE+ + ++ +T L+YE P MKEFEA++LR++ D
Sbjct: 459 KIPDNFYTIVAERHENKKEVKEKIKLP---EVNVDKTELLFYEYPKMKEFEAKILRIVDD 515
Query: 540 WIVLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTNVQKVGKVIVHKVEN-PGLFKEGMEVR 598
+++LD+TAFYPEGGGQ DTG + + +V +VQK ++ HK+EN KEG V+
Sbjct: 516 YVILDRTAFYPEGGGQKADTGYIIKGDKKFRVVDVQKENNIVYHKIENLNDELKEGDIVK 575
Query: 599 GRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTTDWARLDISHYKRISDEEL 658
G IDW RR+ MR+HT TH++ A +VLG+HVWQAGS + D ARLDI+HYKRIS EEL
Sbjct: 576 GVIDWKRRLSLMRNHTATHIINAAAQKVLGRHVWQAGSDVDVDKARLDITHYKRISREEL 635
Query: 659 REIERLANRIVMEDRKVTWEWLPRTEAEQRYGFRLYQGGVVPGRVIRVVKIED-----WD 713
++IER+AN IV+ + + ++ R EAE+++GFR+YQGGVVPG V+R+V IED D
Sbjct: 636 KDIERVANEIVLNNYNIKSIFMDRNEAEEKFGFRIYQGGVVPGNVLRIVIIEDENGNIVD 695
Query: 714 VQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGEAAIKEWQKEREILKKASQVLR 773
VQACGGTH +TG VG IKI++TER+QDGVER+I++ G +A+K Q+ +IL++++++LR
Sbjct: 696 VQACGGTHCQNTGEVGFIKIIKTERVQDGVERLIYSSGLSALKAVQEMEDILEESAEILR 755
Query: 774 VPPEKLPETAERFFNEWKEARKEVEKLKKELAKLLVYELEAKVQKVKEYEFIGEIVEGSM 833
P E+LP+ +RFF EWKE RK++E+L+K++ +L +EL K + + Y+ + E VE +
Sbjct: 756 CPTEELPKVIKRFFEEWKEQRKKIEELEKKIGELKKFELINKFETIGNYKVLVEKVEANP 815
Query: 834 DDLREAVERLKKPNRIVVLVSKEGYFAISVGDNVNLNANDLAKKLTSIAGGGGGGRKDVA 893
++ + L N IVVL++ +G G+NV++ N+L + + GGGR+ +A
Sbjct: 816 KEMLNIADNLATENAIVVLLNDKGNILCKRGENVDIKMNELIRYIAK-----GGGREHLA 870
Query: 894 QGRIK-DVSKAKEAIESIVK 912
QG+ + DV + K+ + +K
Sbjct: 871 QGKYEGDVEEIKKKVIEFIK 890
>sp|O27718|SYA_METTH ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|7437627|pir||A69092 alanine--tRNA ligase (EC
6.1.1.7) - Methanobacterium thermoautotrophicum (strain
Delta H) >gi|2622813|gb|AAB86155.1| (AE000926)
alanyl-tRNA synthetase [Methanobacterium
thermoautotrophicum]
Length = 898
Score = 873 bits (2230), Expect = 0.0
Identities = 441/909 (48%), Positives = 611/909 (66%), Gaps = 27/909 (2%)
Query: 4 IMKTRMFEEEGWIRKKCKVCGKPFWTLDPDRETCGDPPCDEYQFIGKPGIPKKYTLDEMR 63
I + E+ G+ + +C+ CG FW++ +R TCGD PCDEY FIG P + Y L E++
Sbjct: 2 ITMSHQLEKLGYRKYECRSCGNTFWSMK-ERATCGDAPCDEYGFIGNPATDRSYDLYEIQ 60
Query: 64 EKFLKFFEKHEVYPHGRVKRYPVLP-RWRDDVLLVGASIMDFQPWVISGEADPPANPLVI 122
+KF++FF + H ++RYPVL RWRDDV LVGASI +FQPWV SG PPANPLV+
Sbjct: 61 DKFMEFFAERG---HEPIRRYPVLAKRWRDDVFLVGASIYNFQPWVTSGLVKPPANPLVV 117
Query: 123 SQPSIRFTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFEFFTKELKMKP 182
+QPSIR D+DNVG TGRH T F M HHAFN +YW +ET++ +F T + + P
Sbjct: 118 AQPSIRLNDVDNVGRTGRHLTCFTMGGHHAFNSEDNTVYWEEETIKYCHDFLT-HIGIDP 176
Query: 183 EDITFKENPWAGGGNAGPAFEVLYRGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYVPM 242
+ITF E+ W GGGN GP +EV RG+E+ATLVF+QY+ P+ E+ +P+
Sbjct: 177 SEITFIESWWQGGGNEGPCYEVCVRGVELATLVFIQYRTLPDGGREE----------IPL 226
Query: 243 ETKVVDTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSRLAGMF 302
K+VDTGYGLER W+SQGTPTAYDA LG V+E L + GV KIDE IL EN+++AGM
Sbjct: 227 --KIVDTGYGLERFAWISQGTPTAYDACLGPVIEKLVELTGV-KIDEEILAENAQVAGMM 283
Query: 303 DIEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSNVK 362
DIE DL+ LRK+VA+K+GISVEELE+A P E +YAIADHT+ L FMLADGVIPSNVK
Sbjct: 284 DIETYADLRELRKRVADKLGISVEELERAAAPMESVYAIADHTRCLAFMLADGVIPSNVK 343
Query: 363 AGYLARLLIRKSIRHLKELGLEVPLSEIVALHIKELHKTFPEFKEMEDVILEIIDLEEKK 422
GYLARL+IR+++R +K+LG++ L +I+ + ++ L +PE + + IL IIDLEE +
Sbjct: 344 EGYLARLIIRRTLRLMKDLGMKESLKDIMNIQVEFLEGHYPEIRSHHEHILNIIDLEEHR 403
Query: 423 YSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKVHVP 482
Y+ T+KRG +V + I LK+ G +E+PLE LI Y+SHG+ PE + EIAE+ G +V +P
Sbjct: 404 YARTVKRGRRIVEKTIKYLKRDGKAEMPLEILIKLYDSHGIPPETIGEIAEESGFQVKIP 463
Query: 483 DNFYSIVAKEAEKEKEEKEEEVVDFELVKDLPETRTLYYEDPFMKEFEARVLRVIGDWIV 542
DNFY++VA+ E E E EE+V D P T L+Y++P EF+A V+ + + ++
Sbjct: 464 DNFYTLVAERNETETEMPEEDVH-----LDYPATELLFYDEPDDLEFQAEVIGIHENGLI 518
Query: 543 LDQTAFYPEGGGQPYDTGVLFVNGSEVKVTNVQKVGKVIVHKVENPGLFKEGMEVRGRID 602
LD+T FYPEGGGQP DTG + G +++ + +K+G V+VH+ ++ + G +RG ID
Sbjct: 519 LDRTLFYPEGGGQPSDTGYITAEGCRLRIKHAEKIGAVVVHRTDDEICIEPGTTIRGFID 578
Query: 603 WDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTTDWARLDISHYKRISDEELREIE 662
DRR+Q R+HT TH+++ A +VLG H+WQAG+Q +RLD+SHY+RI+ EEL+EIE
Sbjct: 579 SDRRLQLTRNHTATHLIVSAARKVLGDHIWQAGAQKGVKSSRLDLSHYRRITLEELQEIE 638
Query: 663 RLANRIVMEDRKVTWEWLPRTEAEQRYGFRLYQGGVVPGRVIRVVKIEDWDVQACGGTHL 722
RLAN VM + + W+ R AE++YGF LYQGGVVPG IRVV+I DVQAC GTH+
Sbjct: 639 RLANEYVMMNVPLKVRWMDRDLAERKYGFILYQGGVVPGSRIRVVEIPGVDVQACAGTHV 698
Query: 723 PSTGLVGPIKILRTERIQDGVERIIFACGEAAIKEWQKEREILKKASQVLRVPPEKLPET 782
TG +G I+I RTERIQDGVERI F+ G AAI+ QK +IL+++S + +V P +LP T
Sbjct: 699 HRTGDIGLIRINRTERIQDGVERIEFSAGSAAIEIMQKTGDILRESSDIFKVTPSQLPGT 758
Query: 783 AERFFNEWKEARKEVEKLKKELAKLLVYELEAKVQKVKEYEFIGEIVEGSMDDLREAVER 842
ERFF EWK R EV +LK+++A L + E++ + +++ + I + V+ MD+++
Sbjct: 759 CERFFTEWKALRNEVSRLKEKVASLKILEMKDRAERINDLTVIIDTVDADMDEMKNMALE 818
Query: 843 LKKPNRIVVLVSKEGYFAISVGDN---VNLNANDLAKKLTSIAGGGGGGRKDVAQGRIKD 899
L VVL + EG + ++ L N++ + ++ GGGGGGR +AQG
Sbjct: 819 LSATVDAVVLANPEGKIVGAASEDAVKAGLRINEVISQAAAVLGGGGGGRPHLAQGAGPA 878
Query: 900 VSKAKEAIE 908
K EA+E
Sbjct: 879 TDKVDEALE 887
>gi|11499836 alanyl-tRNA synthetase (alaS) [Archaeoglobus fulgidus]
>gi|3334348|sp|O28029|SYA_ARCFU ALANYL-TRNA SYNTHETASE
(ALANINE--TRNA LIGASE) (ALARS) >gi|7437618|pir||G69531
alanyl-tRNA synthetase (alaS) homolog - Archaeoglobus
fulgidus >gi|2648270|gb|AAB89002.1| (AE000949)
alanyl-tRNA synthetase (alaS) [Archaeoglobus fulgidus]
Length = 906
Score = 841 bits (2148), Expect = 0.0
Identities = 437/909 (48%), Positives = 604/909 (66%), Gaps = 28/909 (3%)
Query: 12 EEGWIRKKCKVCGKPFWTLDPDRETCGDPPCDEYQFIGKPGIPKKYTLDEMREKFLKFFE 71
E G++RK+C CGK FWT DP+RE CGDPPC+ Y FIG P K + LDEMRE +L FFE
Sbjct: 15 ENGFVRKRCPKCGKHFWTADPEREICGDPPCESYSFIGNPVFKKPFELDEMREYYLNFFE 74
Query: 72 KHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPANPLVISQPSIRFTD 131
+ HGR++RYPV+ RWR D+ L ASI DFQP+V SG A PPANPL ISQP IR D
Sbjct: 75 RRG---HGRIERYPVVARWRTDIYLTIASIADFQPFVTSGVAPPPANPLTISQPCIRLDD 131
Query: 132 IDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFEFFTKELKMKPEDITFKENP 191
+D+VG TGRH T+FEMMAHHAFNYPGK IYW +ETV E EL +K EDI +KE P
Sbjct: 132 LDSVGRTGRHLTLFEMMAHHAFNYPGKEIYWKNETVAYCTELLN-ELGVKKEDIVYKEEP 190
Query: 192 WAGGGNAGPAFEVLYRGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYVPMETKVVDTGY 251
WAGGGNAGP E + GLEVATLVFM ++ PE E IKG RY M+ +VDTGY
Sbjct: 191 WAGGGNAGPCLEAIVGGLEVATLVFMNLEEHPEGDIE-----IKGARYRKMDNYIVDTGY 245
Query: 252 GLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVE--KIDER---ILMENSRLAGMFDIED 306
GLER VW S+GTPT YDA+ VV+ + + V + DER I+ E+S+LAG+
Sbjct: 246 GLERFVWASKGTPTVYDAIFPEVVDTIIDNSNVSFNREDERVRRIVAESSKLAGIMGELR 305
Query: 307 MGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSNVKAGYL 366
L LRK VA+ VG+SVEELE + P E +Y++ADHT+ + FML DG++PSN AGYL
Sbjct: 306 GERLNQLRKSVADTVGVSVEELEGIVVPLEKVYSLADHTRCILFMLGDGLVPSNAGAGYL 365
Query: 367 ARLLIRKSIRHLKELGLEVPLSEIVALHIKELHKTFPEFKEMEDVILEIIDLEEKKYSET 426
ARL+IR+S+R +EL L + L ++V +H K L EF + EI++LE+++Y T
Sbjct: 366 ARLMIRRSLRLAEELELGLDLYDLVEMHKKILGF---EFDVPLSTVQEILELEKERYRTT 422
Query: 427 LKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKVHVPDNFY 486
+ +G+ LV R + + KK + + LI Y+SHG+ EL IA ++G +V +P + Y
Sbjct: 423 VSKGTRLVERLVERKKK-----LEKDDLIELYDSHGIPVELAVGIAAEKGAEVEMPKDIY 477
Query: 487 SIVAKEAEKEKEEKEEEVVDFELVKDLPETRTLYYEDPFMKEFEARVLRVIGDWIVLDQT 546
+ +AK K ++ +E+++ L + P T LYY+DP + EFEA V+ V GD+++L+++
Sbjct: 478 AELAKRHSKAEKVQEKKIT---LQNEYPATEKLYYDDPTLLEFEAEVIGVEGDFVILNRS 534
Query: 547 AFYPEGGGQPYDTGVLFVNGSEVKVTNVQKVGKVIVHKVENPGLFKEGMEVRGRIDWDRR 606
AFYPE GGQ D G L NG + +V +V + V++H V+ + G +V+G ID D R
Sbjct: 535 AFYPESGGQDNDVGYLIANGGKFEVVDVLEADGVVLHVVKGAKP-EVGTKVKGVIDSDVR 593
Query: 607 IQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTTDWARLDISHYKRISDEELREIERLAN 666
+HMRHH+ THVL+ +L +VLG HVWQAG++ ARLD++H++R S+EE++EIE LAN
Sbjct: 594 WRHMRHHSATHVLLYSLQKVLGNHVWQAGARKEFSKARLDVTHFRRPSEEEIKEIEMLAN 653
Query: 667 RIVMEDRKVTWEWLPRTEAEQRYGFRLYQGGVVPGRVIRVVKIEDWDVQACGGTHLPSTG 726
R ++ ++ + WEW+ R EAE+++GFRLYQGGV PGR IRVV++ D DVQACGGTH STG
Sbjct: 654 REILANKPIKWEWMDRIEAERKFGFRLYQGGVPPGRKIRVVQVGD-DVQACGGTHCRSTG 712
Query: 727 LVGPIKILRTERIQDGVERIIFACGEAAIKEWQKEREILKKASQVLRVPPEKLPETAERF 786
+G +KIL+ E IQDGV R FA GEAAI+ ++ +L++AS +LRV P KLP+T ERF
Sbjct: 713 EIGMLKILKVESIQDGVIRFEFAAGEAAIEAVEEMERLLREASSILRVEPAKLPKTVERF 772
Query: 787 FNEWKEARKEVEKLKKELAKLLVYELEAKVQKVKEYEFIGEIVEGSMDDLREAVERLKKP 846
F EWK+ RKE+E+LK +A L L + ++ + + E+V+ M L++ ERL +
Sbjct: 773 FEEWKDQRKEIERLKSVIADLWADILMERAEEFDSMKVVAEVVDADMQALQKLAERLAEK 832
Query: 847 NRIVVLVSK-EGYFAISVGDNVNLNANDLAKKLTSIAGGGGGGRKDVAQGRIKDVSKAKE 905
+ L++K EG + +A +L +++ +A G GGGRKDVAQG ++ + +E
Sbjct: 833 GAVGCLMAKGEGKVFVVTFSGQKYDARELLREIGRVAKGSGGGRKDVAQGAVQQLLDREE 892
Query: 906 AIESIVKLL 914
++ I + L
Sbjct: 893 MLDVIFRFL 901
>gb|AAG20397.1| (AE005112) alanyl-tRNA synthetase; AlaS [Halobacterium sp. NRC-1]
Length = 929
Score = 756 bits (1932), Expect = 0.0
Identities = 418/939 (44%), Positives = 580/939 (61%), Gaps = 45/939 (4%)
Query: 1 MEFIMKTRMFEEEGWIRKKCKVCGKPFWTLDPDRETCGDPPCDEYQFIGKPGIPKKYTLD 60
+E + FEEEG+ R++C CG FWT D DRETCG+PPC++YQFI PG Y+L
Sbjct: 4 LESAYRLEYFEEEGFHRRECVSCGAHFWTRDGDRETCGEPPCEDYQFIDNPGFDASYSLT 63
Query: 61 EMREKFLKFFEKHEVYPHGRVKRYPVLP-RWRDDVLLVGASIMDFQPWVISGEADPPANP 119
EMR + +FE+ H + YPV RWRDDVLL ASI DFQP V SG + PPANP
Sbjct: 64 EMRSAMVSYFERAG---HDSIDPYPVAANRWRDDVLLTQASIYDFQPHVTSGASPPPANP 120
Query: 120 LVISQPSIRFTDIDNVGITGRHFTIFEMMAHHAFN--------YPGKPIYWIDETVELAF 171
LV+SQP IR DIDNVG TGRH FEM+ HHAFN Y G+ +YW D VE
Sbjct: 121 LVVSQPCIRMQDIDNVGKTGRHTMAFEMLGHHAFNADEGTDYAYDGE-VYWKDTAVEHC- 178
Query: 172 EFFTKELKMKPEDITFKENPWAGGGNAGPAFEVLYRGLEVATLVFMQYKKAPENAPEDQV 231
E ++ + +++TF E+PW GGGNAG AFEV+YRGLE+ATLVFM ++ P+ E +
Sbjct: 179 EGLLADVGVSLDEVTFIEDPWVGGGNAGAAFEVIYRGLELATLVFMSLERDPDGEYEMK- 237
Query: 232 VIIKGDRYVPMETKVVDTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDER- 290
G Y M+ +VVDTGYG+ER WMSQGTPT Y+AV ++ LK AG+E DE
Sbjct: 238 ---DGHTYAEMDRRVVDTGYGVERWTWMSQGTPTVYEAVYPDTIDFLKEQAGIEHTDEEA 294
Query: 291 -ILMENSRLAGMFDIEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALT 349
++ S+ AG DI+++ D++ R +A ++G+ E L + + P E IYAIADH++ L
Sbjct: 295 ELVHRASKHAGNLDIDEVADIEDARAGIAAELGVDAERLTELVAPLEDIYAIADHSRVLA 354
Query: 350 FMLADGVIPSNVKAGYLARLLIRKSIRHLKELGLEVPLSEIVALHIKELHKTFPEFKEME 409
+M DG++PSNV GYLAR+++R++ R + ++G +VPL E+V + L E
Sbjct: 355 YMFGDGIVPSNVGTGYLARMVLRRTKRLVDDIGADVPLDELVDMQADRLGY------ENR 408
Query: 410 DVILEIIDLEEKKYSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVK 469
D I I+ E +KY ETL+RG V + + +G +P ++LI Y+SHG+ P +V
Sbjct: 409 DTIRSIVRSEVEKYGETLERGGRRVEQLAEEYADRG-EPVPTDELIELYDSHGIQPGMVA 467
Query: 470 EIAEKEGIKVHVPDNFYSIVA-KEAEKEKEEKEEEVVDFELVKDLPETRTLYYEDPFMKE 528
+IA G V PD+FYS+VA + + + + + + DLPET TLYY+D + E
Sbjct: 468 DIAADVGATVDAPDDFYSLVAARHDDGDSGAAGGDGGGDDRLADLPETETLYYDDAYGSE 527
Query: 529 FEARVLRVI------GDW---IVLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTNVQKVGK 579
FEA VL V GD +VLDQT FYPEGGGQP DTGVL + V V +VQ+
Sbjct: 528 FEAVVLDVFEREGEDGDGAFDVVLDQTMFYPEGGGQPADTGVLTGDDHTVDVIDVQERDG 587
Query: 580 VIVHKV-ENPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQL 638
V++H+ +NPG +G VRG+ID +RR + M HHT TH+++ A +VLG+HV QAG+Q
Sbjct: 588 VVLHRTTDNPG---KGEFVRGQIDTERRRRLMAHHTATHIVVYAARQVLGEHVRQAGAQK 644
Query: 639 TTDWARLDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFRLYQGGV 698
D +R+D++HY+R+ E ++EIER+AN IV + V EW R EAE YGF LYQGG+
Sbjct: 645 GVDSSRIDVTHYERVDRETVKEIERVANEIVRANTSVQCEWPDRHEAEAEYGFDLYQGGI 704
Query: 699 VPGRVIRVVKIEDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGEAAIKEW 758
G IR+V ++D DVQACGGTH+ TG +G IKIL ER+QDGVER+ FA G AA++
Sbjct: 705 PAGEQIRLVHVDD-DVQACGGTHVARTGEIGSIKILNAERVQDGVERLTFAAGAAAVEHV 763
Query: 759 QKEREILKKASQVLRVPPEKLPETAERFFNEWKEARKEVEKLKKELAKLLVYELEAKVQ- 817
Q + + L+ A++VL V P ++PETAERFF EWK+ K ++ LK++LA+ A +
Sbjct: 764 QGQEDDLRAAAEVLDVTPAEVPETAERFFTEWKDRGKTIDDLKEQLAEARASGGGAGEEV 823
Query: 818 KVKEYEFIGEIVEGSMDDLREAVERLKKPNRIVVLVS--KEGYFAISVGDNVNLNANDLA 875
V + + V+G MD+L+ L ++ V+ S F + V D V +NA ++
Sbjct: 824 DVAGTTAVVQRVDGDMDELQATANALVDGGQVAVVGSGADGAQFVVGVPDGVPVNAGEVV 883
Query: 876 KKLTSIAGGGGGGRKDVAQGRIKDVSKAKEAIESIVKLL 914
+L ++ GGGGGG D AQG D + +A+ +L
Sbjct: 884 GELAAMVGGGGGGPPDFAQGGGPDAERLDDALSRAADVL 922
>gb|AAK40671.1| Alanyl-tRNA synthetase (alaS) [Sulfolobus solfataricus]
Length = 900
Score = 679 bits (1734), Expect = 0.0
Identities = 376/926 (40%), Positives = 557/926 (59%), Gaps = 56/926 (6%)
Query: 6 KTRMFEEEGWIRKKCKVCGKPFWTLDPDRETCGDPPCDEYQFIGKPGIPKKYTLDEMREK 65
K F + + RK CK C PFWT D +E C D PC +Y F + T+ E REK
Sbjct: 9 KLNFFIKNDFKRKICKSCQTPFWTKDDKKEYCSDIPCTDYYFFDINIKSQPLTVKEAREK 68
Query: 66 FLKFFEKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPANPLVISQP 125
FL FFEK H R+ PVL RWR+D+ L ASI+DFQP V SG PPANPLV+SQP
Sbjct: 69 FLSFFEKRG---HTRIPPKPVLARWREDLYLTIASIVDFQPHVTSGLVPPPANPLVVSQP 125
Query: 126 SIRFTDIDNVGIT-GRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFEFFTKELKMKPED 184
SIR DIDNVG+T GRH T FEM AHHAFNYP + +YW DET A EFFTKEL + E+
Sbjct: 126 SIRLEDIDNVGVTFGRHLTTFEMAAHHAFNYPDRYVYWKDETTAYATEFFTKELGIPEEE 185
Query: 185 ITFKENPWAGGGNAGPAFEVLYRGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYVPMET 244
+ FKE+ W GGGNAGP EV GLE+ATLVFMQYK + GD Y+P++
Sbjct: 186 LNFKESWWEGGGNAGPCLEVTVGGLELATLVFMQYK-----------ITDNGD-YIPLKL 233
Query: 245 KVVDTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSRLAGMFDI 304
K+VDTGYG+ER+ W++Q TP+A+ A+ G +V GV IDE +L SR AG D
Sbjct: 234 KIVDTGYGVERIAWVTQKTPSAFHAIYGNLVYKFFDKIGVAYIDETLLKVASRFAGKIDP 293
Query: 305 EDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSNVKAG 364
++ +K+ R+ V++++GI ++ +E+ + ++ I DHTK + MLADG++PSN G
Sbjct: 294 DNPDTIKIHRQMVSKELGIDIKNVEEELDRAAKVFQILDHTKTIMLMLADGLVPSNSGEG 353
Query: 365 YLARLLIRKSIRHLKELGLEVPLSEIVALHIKELHKTFPEFKEMEDVILEIIDLEEKKYS 424
YL RL+IR++++ L+ L +V L E+V I + FP+ + +D IL+ ++LE++++
Sbjct: 354 YLGRLVIRRALKVLRLLKSDVRLYELVKEQIGFWKEDFPQVLKNKDYILDAVELEQQRFE 413
Query: 425 ETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKVHVPDN 484
+ L++ + + L +K SEI E LI Y+S+G+ P+L++E +K+ +K +P N
Sbjct: 414 KILEKVPSIA----STLARK--SEITTEDLIQVYDSNGVPPDLLEEELKKKRVKFELPRN 467
Query: 485 FYSIVAKEAEKEKEEKEEEVVDF-----ELVKDLPETRTLYYEDPFMKEFEARVLRVIGD 539
FY++VAK + + + V E + L T LYY+D +M+ FE +VL + +
Sbjct: 468 FYALVAKRHQTSTIKNVYDKVKLPKDLLEYITTLQPTEKLYYKDQYMRSFEGKVLGIYKN 527
Query: 540 WIVLDQTAFYPEGGGQPYDTGVLFVNGSEVK--VTNVQKVGKVIVHKV-ENPGLFKEGME 596
+++LD+T FYPEGGGQ DTG++ S + V + QKV VI+H + E P K G
Sbjct: 528 YLILDKTTFYPEGGGQLGDTGLIIDEKSSKRYEVVDTQKVNDVIIHVLKEEPSTIKVGDN 587
Query: 597 VRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTTDWARLDISHYKRISDE 656
VRG I+W+RR + MRHHT THV++ A +VLG H+WQAG++ T + RLDI+H+K +++E
Sbjct: 588 VRGEINWERRYRLMRHHTVTHVILAAAKKVLGDHIWQAGAEKTPEKGRLDITHHKALTEE 647
Query: 657 ELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFRLYQGGVVPGRVIRVVKIEDWDVQA 716
E++ IE AN ++ + R V + R EAE +YG +Y+GGV IR+++I+DWD+++
Sbjct: 648 EVKLIENYANSVISDRRPVKPLEMNRMEAEMKYGVSIYEGGVPNSATIRLLEIKDWDIES 707
Query: 717 CGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGEAAIKEWQKEREILKKASQVLRVPP 776
CGGTH+ +T +G +KI+ ERIQDG+ R+ + G A + ++ + +AS+++ P
Sbjct: 708 CGGTHVSNTSEIGAVKIINVERIQDGIIRLEYVAGPALVDYIRETEAKIAEASKIIGTSP 767
Query: 777 EKLPETAERFFNEWKEARKEVEKLKKELAKLLVYELEAKVQKVKEYEFIGE---IVEGSM 833
++LP R NE ++ + + ++ + E E + +K YE G I+EG +
Sbjct: 768 DQLPSRLRRILNEVEKKNNLIIQYRR------IVETEL-LNSLKPYEINGNKIYIIEG-L 819
Query: 834 DDLREAVERLKKPNRIVVLVSKEGYFAISVGDN-------VNLNANDLAKKLTSIAGGGG 886
+D E E L+K L S + AIS+ DN N+ + + ++L + GGG
Sbjct: 820 NDEEENKEILRK------LTSTDNTIAISISDNRLQIATSKNMRVDKIVEEL--LKGGGK 871
Query: 887 GGRKDVAQGRIKDVSKAKEAIESIVK 912
GG K I K+KE I IV+
Sbjct: 872 GGGKGTFANVILSSKKSKEEIIDIVR 897
>sp|Q9Y9X3|SYA_AERPE ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|7437623|pir||A72524 probable alanyl-tRNA synthetase
APE2166 - Aeropyrum pernix (strain K1)
>gi|5105865|dbj|BAA81177.1| (AP000063) 900aa long
hypothetical alanyl-tRNA synthetase [Aeropyrum pernix]
Length = 900
Score = 671 bits (1713), Expect = 0.0
Identities = 374/921 (40%), Positives = 542/921 (58%), Gaps = 46/921 (4%)
Query: 14 GWIRKKCKVCGKPFWTLDPDRETCGDPPCDEYQFIGKPGIPKKYTLDEMREKFLKFFEKH 73
G++RK+ C + FWTL+P+ D PC EY F K ++ E RE FL FFEKH
Sbjct: 2 GFVRKEGARCREAFWTLNPEFSEPQDTPCVEYWF-DKVKSVSGMSVGEAREAFLSFFEKH 60
Query: 74 EVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPANPLVISQPSIRFTDID 133
H RV PV+ RWR+D+ L ASI+ FQP V SG PPANPLVISQPSIR DID
Sbjct: 61 G---HTRVPPRPVVARWREDLYLTIASIVVFQPHVTSGLVPPPANPLVISQPSIRLEDID 117
Query: 134 NVGIT-GRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFEFFTKELKMKPEDITFKENPW 192
NVGIT GRH T FEM AHHAFNYP + +YW +ETV LAFEFFT+ L + PE I FKE+ W
Sbjct: 118 NVGITIGRHLTSFEMAAHHAFNYPDRQVYWKEETVRLAFEFFTQVLGIPPELIVFKESWW 177
Query: 193 AGGGNAGPAFEVLYRGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYVPMETKVVDTGYG 252
GGGNAGP+FEV GLE+ATLVFM+Y+ ++ G RY + K+VDTGYG
Sbjct: 178 EGGGNAGPSFEVAVGGLELATLVFMKYR------------VVDG-RYEEIPLKIVDTGYG 224
Query: 253 LERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSRLAGMFDIEDMGDLKL 312
+ERL W +Q TPTA+ A+ G +V+ +RM GVEK DE ++ R+AG D ED L+
Sbjct: 225 VERLAWFTQKTPTAFHAIYGSLVDDFRRMLGVEKPDENVMWAAFRVAGFLDPEDPESLRN 284
Query: 313 LRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSNVKAGYLARLLIR 372
+ VA G VE + + +Y++ DHTK + ML DG++PSN GYLARL++R
Sbjct: 285 YYQTVASLAGGDVETVRSILTREARLYSVLDHTKTIALMLGDGIVPSNSGEGYLARLVVR 344
Query: 373 KSIRHLKELGLEVPLSEIVALHIKELHKTFPEFKEMEDVILEIIDLEEKKYSETLKRGSD 432
+++R L L EVPL ++V + + FP+ KE D IL+ + LEE+++ + L++
Sbjct: 345 RALRQLSLLNAEVPLVDLVERQARFWMRDFPQLKENLDYILDAVSLEEERFRDVLRKARS 404
Query: 433 LVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKVHVPDNFYSIVAKE 492
+V RE+ + K+ G+ + LI Y+S G+ PE+ EIA G V VP NFYS+VA
Sbjct: 405 IVERELKRKKRLGVDD-----LIRLYDSMGVPPEIAAEIAASRGAPVEVPHNFYSLVAAR 459
Query: 493 AEKEKEEKEEEVVDFELVKDLPE-------TRTLYYEDPFMKEFEARVLRVIGDWIVLDQ 545
++ + + L +D+ E TR +++EDP+ K ++ARVL V G ++V D
Sbjct: 460 HRGPEKIRGYGFDETGLPRDVEEWARRFGETRRVFHEDPYAKAWKARVLGVKGRYLVADS 519
Query: 546 TAFYPEGGGQPYDTGVLFVNGSEVKVTNVQKVGKVIVHKVENPGLFKEGMEVRGRIDWDR 605
T FYP GGGQ +DTGV+ VN + ++ +VQKVG IVH E + G EV IDW+R
Sbjct: 520 TIFYPTGGGQIHDTGVIRVNNQQYRIIDVQKVGDAIVHVAEREIAAEPGDEVWMEIDWER 579
Query: 606 RIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTTDWARLDISHYKRISDEELREIERLA 665
R MRHHT THVL+ A RVLG+H WQAG++ T + RLDI+H++ ++ +++ ++E +
Sbjct: 580 RYSIMRHHTVTHVLIAAARRVLGRHAWQAGAEKTEEKGRLDITHHRPLTRDDIEKLENVV 639
Query: 666 NRIVMEDRKVTWEWLPRTEAEQRYGFRLYQGGVVPGRVIRVVKIEDWDVQACGGTHLPST 725
N+++ E R+V + + + EAE++YGF +YQGGV + +R+V +EDWDV+AC GTH+ +T
Sbjct: 640 NQVIRERRRVWEDMVDKNEAEEKYGFTIYQGGVPMEKRLRLVFVEDWDVEACFGTHVRNT 699
Query: 726 GLVGPIKILRTERIQDGVERIIFACGEAAIKEWQKEREILKKASQVLRVPPEKLPETAER 785
G +G KI+ RIQDGV R+ + G+ ++ E L + ++ P + +
Sbjct: 700 GEIGGFKIISYSRIQDGVVRLEYVAGDRVAIYARELEERLARIGDAVKAPRGQEEARVKG 759
Query: 786 FFNEWKEARKEVEKLKKELAKLLVYELEAKVQKVKEYEFIGEIVEGSMDDLREAVERLKK 845
++AR+++++ + K + ++ ++V + + VE D R E L+K
Sbjct: 760 LIASLEQAREDLKRYRDYWVKTIEEAYISRARRVNGVKVLA--VESLEKDRRTVQEILRK 817
Query: 846 PNR------IVVLVSKEGYFAISV------GDNVNLNANDLAKKLTSIAGGGGGGRKDVA 893
++V EG + + + V+L A L K + GG GGGR A
Sbjct: 818 LTSRHEDLIAALVVENEGNTQVEIAAGPKAAEKVDLGA--LVKIVIKKVGGRGGGRGSYA 875
Query: 894 QGRIKDVSKAKEAIESIVKLL 914
R++ A + E + L
Sbjct: 876 SLRVEGRLSADKVEELLADAL 896
>emb|CAC11978.1| (AL445065) alanyl-tRNA synthetase related protein [Thermoplasma
acidophilum]
Length = 871
Score = 659 bits (1683), Expect = 0.0
Identities = 366/880 (41%), Positives = 530/880 (59%), Gaps = 52/880 (5%)
Query: 10 FEEEGWIRKKCKVCGKPFWTLDPDRETCGDPPCDEYQFIGKPGIPKKYTLDEMREKFLKF 69
F G+ +K+C CG FWT D +R TCGD PCDEY FIG +PK Y+L EMR+ F+KF
Sbjct: 13 FLNSGFEKKQCIKCGSYFWTQDKERNTCGDTPCDEYTFIGNSPVPKSYSLSEMRDAFIKF 72
Query: 70 FEKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPANPLVISQPSIRF 129
FEK H +K YPV+PRWR+DVLLV ASI DFQP V SG PP NP+V+SQPSIR
Sbjct: 73 FEKRG---HKFLKPYPVVPRWREDVLLVNASIYDFQPHVTSGIVRPPGNPIVMSQPSIRM 129
Query: 130 TDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFEFFTKELKMKPEDITFKE 189
D+D VGITGRH T FEM+ H +FN K +YW +ETV ++F T+ L + + I+FKE
Sbjct: 130 NDVDLVGITGRHLTSFEMLCHDSFNTKDKTVYWKEETVHYCYDFLTEGLGIDGKLISFKE 189
Query: 190 NPWAGGGNAGPAFEVLYRGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYVPMETKVVDT 249
PW+GGGNAG A EV RGLEVATLVFM K+ P N P + I G RY M+ ++VDT
Sbjct: 190 KPWSGGGNAGNALEVFVRGLEVATLVFMDMKEDP-NGPYE----IDGIRYSKMDMRIVDT 244
Query: 250 GYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSRLAGMFD-IEDMG 308
GYGLERL W+SQGTPT Y A+ +++ + + + V IDE L E + + M + E+
Sbjct: 245 GYGLERLTWLSQGTPTVYQAIYPDIIQHVMKNSSVSDIDEEFLSEVVKASVMKEPYEESF 304
Query: 309 DLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSNVKAGYLAR 368
+ L K+ + + + I+ ++ + DH ++L M A VIPSNVK GYLAR
Sbjct: 305 VISQLEKRYPD-----ARQRFEEIKKVRDVFLMIDHARSLMHMFAAYVIPSNVKVGYLAR 359
Query: 369 LLIRKSIRHLKELGLEVPLSEIVALHIKELHKTFPEFKEMEDVILEIIDLEEKKYSETLK 428
+LIR++ R + G L +++ ++ ++L P+F E + +++ +EE+KY + +
Sbjct: 360 MLIRRAYRAISNTGYRGSLMDLIRMNHEDLKDIVPDFP--EQFVSDVLSIEEEKYRDVER 417
Query: 429 RGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKVHVPDNFYSI 488
G+ ++ + I+ KG ++ L+ L+ Y+SHG++PE VK E +G+++ VPDNF++I
Sbjct: 418 HGTQIIDKMIS---NKG--KLSLDDLVLLYDSHGISPETVKAYLETKGMEIDVPDNFHAI 472
Query: 489 VAKEAEKEKEEKEEEVVDFELVKDLP--ETRTLYYEDPFMKEFEARVLRVIGDWIVLDQT 546
V K EK + EK++ D P ETRTLYY+DPFM+EF VL G+ I+LD+T
Sbjct: 473 VIKRHEKGETEKKK-------YSDYPEIETRTLYYDDPFMREFTGLVLFSKGNEIILDKT 525
Query: 547 AFYPEGGGQPYDTGVLFVNGSEVKVTNVQKVGKVIVHKVENPGLFKEGMEVRGRIDWDRR 606
AFYPEGGGQP+D G G + V V+K GK IVH ++ G +G+ V G IDW+RR
Sbjct: 526 AFYPEGGGQPWDLGYFEYKGKRINVVAVRKYGKTIVHTLD--GEIPQGVRVHGVIDWERR 583
Query: 607 IQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTTDWARLDISHYKRISDEELREIERLAN 666
+ M HHT TH+L+G L VLG+HVWQ G Q + +RLDI+HY++I +E +R+IE
Sbjct: 584 SRLMVHHTSTHLLLGVLREVLGEHVWQNGVQKDVEESRLDITHYRKIDEETIRKIEERVF 643
Query: 667 RIVMEDRKVTWEWLPRTEAEQRYGFRLYQGGVVPGRVIRVVKIEDWDVQACGGTHLPSTG 726
++ E R+V+ L A +YGFRL++GGV IRVV+I+ D + CGGTHL +
Sbjct: 644 DLIREGREVSVRNLDWYSAIDKYGFRLFEGGVPLTPKIRVVEIQGVDAEGCGGTHLKNIS 703
Query: 727 LVGPIKILRTERIQDGVERIIFACGEAAIKEWQKEREILKKASQVLRVPPEKLPETAERF 786
+G +KI + E IQ+ + RI F+ G A+ +Q+ E S +L+ P E++ ++
Sbjct: 704 SIGVLKIRKVEAIQENIYRITFSAGVPALHLFQESYEASYGISTLLKKPIEEIAQSV--- 760
Query: 787 FNEWKEARKEVEKLKKELAKLLVYELEAKVQKVKEYEFIG---EIVEGSMDDLREAVERL 843
E K L++ LA+ ++E ++ K+ G I+E D+ E + R+
Sbjct: 761 ----SELSKGYADLRRSLAEARRRDIENRIANAKKIGTPGAEYPIIEADDADIGE-ISRI 815
Query: 844 KKPNRIVVLV-----SKEGYFAISVGDNVNLNANDLAKKL 878
++ ++V K Y AIS + A D+ +KL
Sbjct: 816 AHSRKVDLIVETRIAGKFKYTAIS----PSKKARDMIRKL 851
>gb|AAG23137.1|AF245445_1 (AF245445) alanyl-tRNA synthetase [Giardia intestinalis]
Length = 954
Score = 449 bits (1143), Expect = e-125
Identities = 276/832 (33%), Positives = 437/832 (52%), Gaps = 66/832 (7%)
Query: 9 MFEEEGWIRKKCKVCGKPFWTLDPDRETCGDPPC-DEYQFIGKPGIPKKYTLDEMREKFL 67
+F++ G+ R C CG +W R CGD C EY F KP +K MR +
Sbjct: 21 VFDDFGFKRHICPKCGTLYWRRTELRTICGDSECLGEYSFFDKP--ERKDDPWSMRRVWN 78
Query: 68 KFFEKH-EVYP-HGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPANPLVISQP 125
F + + P H V RYPV+ RWRDD A I +QP+ ++GE +PPANPL+ Q
Sbjct: 79 SFAQSFTQTTPAHTIVPRYPVVARWRDDCEFTAAGIQCYQPFCVTGEIEPPANPLIQPQL 138
Query: 126 SIRFTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFEFFTKELKMKPEDI 185
+RF D+D++G++GRH++ F M+ FN K +Y+ +E + E+ + + + +++
Sbjct: 139 CLRFNDLDSIGLSGRHYSGFTMLGIQVFNTSTKYVYFKEEIIRFNLEWL-QTMGIDLDEV 197
Query: 186 TFKENPWAGGGNAGPAFEVLYRGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYVPMETK 245
T + WAGGGN GP E GLEV +VFM++K + E P+ +
Sbjct: 198 TLIADVWAGGGNLGPCVEYFMHGLEVGNMVFMEFKAFADGTIE------------PLPVQ 245
Query: 246 VVDTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGV--EKIDERILMENSRLAGMFD 303
VVD G GLER+ W+ + T+Y ++ + ++ G+ + I+ + R + + +
Sbjct: 246 VVDVGIGLERIPWLLNRSVTSYITAFPTALKQMSQLIGITDDVINGDVWRRFGRYSCLLN 305
Query: 304 IEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSNVKA 363
I+++ D+ + E+ G++ E++ I P +Y + DH ++L + DG +PSNV
Sbjct: 306 IDEVSDISQAWALIKERTGLTTEDITNVIEPVRQMYIVLDHLRSLMVAIQDGALPSNVGG 365
Query: 364 GYLARLLIRKSIRHLKE------LGLEVPLSEIVALHIKELHK-----TFPEFKEMEDVI 412
G R ++R+ L +G L +I+ H ++L + +FP FK + V+
Sbjct: 366 GNNLRNVLRRVFHILVSRGWWDAIGGIDGLCQIIDYHRQDLEEVHGAGSFPPFKPLRAVL 425
Query: 413 LEIIDLEEKKYSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIA 472
+LE +++ T K D ++ KL KKG + +E +T + GL + V E+
Sbjct: 426 ----ELEYTRWTTTDKDARD----KVEKLLKKGKGHLSIEDWVTIVTTFGLNADQVSELT 477
Query: 473 EKEGIKVHVPDNFYSIVAKEAEKEKEEKEEEVVDFELVKDLPETRTLYYEDPFMKEF--- 529
+ VP+N YS VA++ +EK + V LP T +YY P+ ++
Sbjct: 478 G-----IPVPENLYSHVAEQ--QEKNAIKVAVAQLYDTVSLPPTDCVYYTKPYGEKLRKL 530
Query: 530 -EARVLRVIGDW---------IVLDQTAFYPEGGGQPYDTGVL---FVNGSEV--KVTNV 574
+A+V+ + + ++LD+T FYP GGQ +DTGVL NG + V +V
Sbjct: 531 ADAKVVSIFANMEDKSKGRNLVILDKTVFYPTSGGQQHDTGVLKFLLGNGKMIIHDVVDV 590
Query: 575 QKVGKVIVHKVENP--GLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVW 632
+KVG ++H++ P +G V ID RR Q M HHT HV+ +VLG HVW
Sbjct: 591 RKVGHCVMHELNAPVADSIVQGTSVSMAIDSARRDQLMCHHTAAHVIHATANKVLGPHVW 650
Query: 633 QAGSQLTTDWARLDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFR 692
QAG++ TT+ A LDI+HY+ ++ +E R IER ANR++ ++ + LP+ EAE++YGF
Sbjct: 651 QAGAKKTTEVATLDITHYRSLTFDEERAIEREANRMIRDNIPIRKYQLPKNEAEKKYGFS 710
Query: 693 LYQGGVVPGRVIRVVKIEDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGE 752
LYQGGVVPG +R V I D D +AC GTHL +TG +G I+I+++ RI DGV R+ F GE
Sbjct: 711 LYQGGVVPGSTVRCVDITDHDTEACCGTHLDNTGKIGLIRIVKSTRISDGVVRLTFVAGE 770
Query: 753 AAIKEWQKEREILKKASQVLRVPPEKLPETAERFFNEWKEARKEVEKLKKEL 804
A+ + EIL V + +T ++FF K +L+ EL
Sbjct: 771 RALDFTDTQSEILHTQMDRWGVDQAGIVKTGDKFFTAMKRLENLTVQLRGEL 822
>gb|AAF05594.1|AF188719_1 (AF188719) alanyl-tRNA synthetase [Giardia intestinalis]
Length = 969
Score = 448 bits (1139), Expect = e-124
Identities = 275/832 (33%), Positives = 437/832 (52%), Gaps = 66/832 (7%)
Query: 9 MFEEEGWIRKKCKVCGKPFWTLDPDRETCGDPPC-DEYQFIGKPGIPKKYTLDEMREKFL 67
+F++ G+ R C CG +W R CGD C EY F KP +K MR +
Sbjct: 36 VFDDFGFKRHICPKCGTLYWRRTELRTICGDSECLGEYSFFDKP--ERKDDPWSMRRVWN 93
Query: 68 KFFEKH-EVYP-HGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPANPLVISQP 125
F + + P H V RYPV+ RWRDD A I +QP+ ++GE +PPANPL+ Q
Sbjct: 94 SFAQSFTQTTPAHTIVPRYPVVARWRDDCEFTAAGIQCYQPFCVTGEIEPPANPLIQPQL 153
Query: 126 SIRFTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFEFFTKELKMKPEDI 185
+RF D+D++G++GRH++ F M+ FN K +Y+ +E + E+ + + + +++
Sbjct: 154 CLRFNDLDSIGLSGRHYSGFTMLGIQVFNTSTKYVYFKEEIIRFNLEWL-QTMGIDLDEV 212
Query: 186 TFKENPWAGGGNAGPAFEVLYRGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYVPMETK 245
T + WAGGGN GP E GLEV +VFM++K + E P+ +
Sbjct: 213 TLIADVWAGGGNLGPCVEYFMHGLEVGNMVFMEFKAFADGTIE------------PLPVQ 260
Query: 246 VVDTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGV--EKIDERILMENSRLAGMFD 303
VVD G GLER+ W+ + T+Y ++ + ++ G+ + I+ + R + + +
Sbjct: 261 VVDVGIGLERIPWLLNRSVTSYITAFPTALKQMSQLIGITDDVINGDVWRRFGRYSCLLN 320
Query: 304 IEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSNVKA 363
I+++ D+ + E+ G++ E++ I P +Y + DH ++L + DG +PSNV
Sbjct: 321 IDEVSDISQAWALIKERTGLTTEDITNVIEPVRQMYIVLDHLRSLMVAIQDGALPSNVGG 380
Query: 364 GYLARLLIRKSIRHLKE------LGLEVPLSEIVALHIKELHK-----TFPEFKEMEDVI 412
G R ++R+ L +G L +I+ H ++L + +FP FK + V+
Sbjct: 381 GNNLRNVLRRVFHILVSRGWWDAIGGIDGLCQIIDYHRQDLEEVHGAGSFPPFKPLRAVL 440
Query: 413 LEIIDLEEKKYSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIA 472
+LE +++ T K D ++ KL KKG + +E +T + GL + V E+
Sbjct: 441 ----ELEYTRWTTTDKDARD----KVEKLLKKGKGHLSIEDWVTIVTTFGLNADQVSELT 492
Query: 473 EKEGIKVHVPDNFYSIVAKEAEKEKEEKEEEVVDFELVKDLPETRTLYYEDPFMKEF--- 529
+ VP+N YS VA++ +EK + V LP T +YY P+ ++
Sbjct: 493 G-----IPVPENLYSHVAEQ--QEKNAIKVAVAQLYDTVSLPPTDCVYYTKPYGEKLRKL 545
Query: 530 -EARVLRVIGDW---------IVLDQTAFYPEGGGQPYDTGVL---FVNGSEV--KVTNV 574
+A+V+ + + ++LD+T FYP GGQ +DTGVL NG + V +V
Sbjct: 546 ADAKVVSIFANMEDKSKGRNLVILDKTVFYPTSGGQQHDTGVLKFLLGNGKMIIHDVVDV 605
Query: 575 QKVGKVIVHKVENP--GLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVW 632
+KVG ++H++ P +G V ID RR Q M HHT HV+ +VLG HVW
Sbjct: 606 RKVGHCVMHELNAPVADSIVQGTSVSMAIDSARRDQLMCHHTAAHVIHATANKVLGPHVW 665
Query: 633 QAGSQLTTDWARLDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFR 692
QAG++ TT+ A LDI+HY+ ++ +E R IER ANR++ ++ + LP+ +AE++YGF
Sbjct: 666 QAGAKKTTEVATLDITHYRSLTFDEERAIEREANRMIRDNIPIRKYQLPKNKAEKKYGFS 725
Query: 693 LYQGGVVPGRVIRVVKIEDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGE 752
LYQGGVVPG +R V I D D +AC GTHL +TG +G I+I+++ RI DGV R+ F GE
Sbjct: 726 LYQGGVVPGSTVRCVDITDHDTEACCGTHLDNTGKIGLIRIVKSTRISDGVVRLTFVAGE 785
Query: 753 AAIKEWQKEREILKKASQVLRVPPEKLPETAERFFNEWKEARKEVEKLKKEL 804
A+ + EIL V + +T ++FF K +L+ EL
Sbjct: 786 RALDFTDTQSEILHTQMDRWGVDQAGIVKTGDKFFTAMKRLENLTVQLRGEL 837
>sp|O67323|SYA_AQUAE ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|7437619|pir||H70411 alanine--tRNA ligase (EC
6.1.1.7) - Aquifex aeolicus >gi|2983727|gb|AAC07289.1|
(AE000733) alanyl-tRNA synthetase [Aquifex aeolicus]
Length = 867
Score = 340 bits (862), Expect = 5e-92
Identities = 277/935 (29%), Positives = 460/935 (48%), Gaps = 157/935 (16%)
Query: 61 EMREKFLKFFEKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPANPL 120
E+RE FL FFEK H RVK P++P +L V A ++ F+ V G P
Sbjct: 7 EIRELFLSFFEKKG---HTRVKSAPLVPENDPTLLFVNAGMVPFKN-VFLGLEKRPYKRA 62
Query: 121 VISQPSIRFT----DIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFEFFTK 176
Q +R + D++ VG T RH T FEM+ + +F Y+ E +E A+EF T+
Sbjct: 63 TSCQKCLRVSGKHNDLEQVGYTSRHHTFFEMLGNFSFGD-----YFKKEAIEYAWEFVTE 117
Query: 177 ELKMKPEDITF-----------------------------KENPWAGG--GNAGPAFEVL 205
LK+ E + ++N W G G GP+ E+
Sbjct: 118 VLKLPKEKLYVSVYKDDEEAYRIWNEHIGIPSERIWRLGEEDNFWQMGDVGPCGPSSEIY 177
Query: 206 ------YRG----LEVATLVFMQYKKAPENAPEDQVVIIKGDRYVPMETKVVDTGYGLER 255
Y G LE+ LVFMQY N E+ V+ P+ +DTG GLER
Sbjct: 178 VDRGEEYEGDERYLEIWNLVFMQY-----NRDENGVL-------TPLPHPNIDTGMGLER 225
Query: 256 LVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSRLAGMFDIEDMGDLKLLRK 315
+ + QG + ++ + +F + G+ ++ K
Sbjct: 226 IASVLQGKNSNFEIDI-----------------------------IFPLIQFGE-EVSGK 255
Query: 316 KVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSNVKAGYLARLLIRKSI 375
K EK E + A+R IADH +A+TF ++DGVIPSN GY+ R ++R+++
Sbjct: 256 KYGEKF-----ETDVALR------VIADHLRAITFAISDGVIPSNEGRGYVIRRILRRAM 304
Query: 376 RHLKELGLEVP-LSEIVALHIKELHKTFPEFKEMEDVILEIIDLEEKKYSETLKRGSDLV 434
R +LG+E P L + V L + + + +PE + + + I+ EEK++ +TLK G + +
Sbjct: 305 RFGYKLGIENPFLYKGVDLVVDIMKEPYPELELSREFVKGIVKGEEKRFIKTLKAGMEYI 364
Query: 435 RREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKVHVPDNFYSIVAKEAE 494
+ I K ++G + +++ T Y+++G +L+ EIA ++G+ + + + F + ++ E
Sbjct: 365 QEVIQKALEEGRKTLSGKEVFTAYDTYGFPVDLIDEIAREKGLGIDL-EGFQCELEEQRE 423
Query: 495 KEKEEKEEEVVDFELV----KDLPETRTLY-YEDPFMKEFEARVLRVI------------ 537
+ ++ + E + V K+L +T YE E+E++V+ ++
Sbjct: 424 RARKHFKVEAKKVKPVYSHLKELGKTSAFVGYEH---MEWESQVVGLVKGEGLVSELKEG 480
Query: 538 --GDWIVLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTNVQKVGK-VIVH--KVENPGLFK 592
G+ +VL +T FYPEGGGQ D G++ + + KV + QK + +IVH KV G K
Sbjct: 481 EEGE-VVLKETPFYPEGGGQIGDAGIIESDKALFKVEDTQKPTEGIIVHIGKVLK-GTLK 538
Query: 593 EGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTTDWARLDISHYKR 652
G V R+D +RR MR+HT TH+L AL VLG+HV QAGS + + R D +H+
Sbjct: 539 VGDTVHARVDKERRWDIMRNHTATHLLHAALRNVLGEHVRQAGSLVADKYLRFDFTHFSA 598
Query: 653 ISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFRLYQGGVVP-----GRVIRVV 707
+++EEL+ +E L N + E+ LP E Y L G + G +RV+
Sbjct: 599 LTEEELKRVEELVNEKIREN-------LPVNVMEMAYDEALKTGAIAIFEEKYGERVRVI 651
Query: 708 KIEDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGEAAIKEWQKEREILKK 767
++ + CGGTH+ +TG +G KI+ + GV RI+ G +++ KE + LKK
Sbjct: 652 SCGEFSKELCGGTHVSATGDIGYFKIISESSVGAGVRRIVAQTGRWSVETAFKEHQTLKK 711
Query: 768 ASQVLRVPPEKLPETAERFFNEWKEARKEVEKLKKELAKLLVYELEAKVQKVKEYEF-IG 826
AS L V E++ + E E K+ +E+++LK+EL KL + E+ K + V ++ G
Sbjct: 712 ASSALGVGEEEVIQKIEELKEEIKDREREIQRLKQELLKLQIREV-VKEENVGDFTLHYG 770
Query: 827 EIVEGSMDDLREAVERLKKPNR--IVVLVSKEG---YFAISVGDNVN--LNANDLAKKLT 879
E ++LR + L++ + +V + S++G F I V ++ +NA ++ +++
Sbjct: 771 VFEEVEPEELRNLADMLRQRTKKDVVFIASRKGDKINFVIGVSKEISDKVNAKEVIREVG 830
Query: 880 SIAGGGGGGRKDVAQGRIKDVSKAKEAIESIVKLL 914
+ GGGGGR D+AQG K K EA++ + ++L
Sbjct: 831 KVLKGGGGGRADLAQGGGKAPDKFPEAVKLLKEIL 865
>sp|Q9XDM3|SYA_AQUPY ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|4587716|gb|AAD25871.1|AF027500_1 (AF027500)
alanyl-tRNA synthetase; alanine-tRNA ligase [Aquifex
pyrophilus]
Length = 871
Score = 332 bits (843), Expect = 9e-90
Identities = 273/941 (29%), Positives = 461/941 (48%), Gaps = 161/941 (17%)
Query: 57 YTLDEMREKFLKFFEKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPP 116
++ E+RE FL FFEK H RVK P++P +L V A ++ F+ V G P
Sbjct: 3 FSAHEIRELFLSFFEKKG---HTRVKSAPLVPENDPTLLFVNAGMVPFKN-VFLGLEKRP 58
Query: 117 ANPLVISQPSIRFT----DIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFE 172
Q +R + D++ VG T RH T FEM+ + +F Y+ E +E A+E
Sbjct: 59 YKRATSCQKCLRVSGKHNDLEQVGYTSRHHTFFEMLGNFSFGD-----YFKKEAIEYAWE 113
Query: 173 FFTKELKMKPEDITF-----------------------------KENPWAGG--GNAGPA 201
F T+ LK+ E + ++N W G G GP+
Sbjct: 114 FVTEVLKLPKERLYVSVYKDDEEAYRIWNEHIGIPSERIWRLGEEDNFWQMGDTGPCGPS 173
Query: 202 FEVL------YRG----LEVATLVFMQYKKAPENAPEDQVVIIKGDRYVPMETKVVDTGY 251
E+ Y G LE+ LVFMQY N E+ V+ P+ +DTG
Sbjct: 174 SEIYVDRGEEYEGEERYLEIWNLVFMQY-----NRDENGVL-------TPLPHPNIDTGM 221
Query: 252 GLERLVWMSQGTPTAYDAVLGY-VVEPLKRMAGVEKIDERILMENSRLAGMFDIEDMGDL 310
GLER+ + QG + ++ + Y ++E + ++G
Sbjct: 222 GLERIASVLQGKNSNFEIDIIYPLIEFGEEVSG--------------------------- 254
Query: 311 KLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSNVKAGYLARLL 370
KK EK E + A+R IADH +A+TF ++DGVIPSN GY+ R +
Sbjct: 255 ----KKYGEKF-----ETDVALR------VIADHLRAITFAISDGVIPSNEGRGYVIRRI 299
Query: 371 IRKSIRHLKELGLEVP-LSEIVALHIKELHKTFPEFKEMEDVILEIIDLEEKKYSETLKR 429
+R+++R +LG+ P L + + L + + + +PE + D + I+ EE+++ TL+
Sbjct: 300 LRRAMRFGYQLGITEPFLYKGIDLVVDIMKEPYPELELSRDFVKGIVKGEEERFIRTLRS 359
Query: 430 GSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKVHVPDNFYSIV 489
G + ++ I K +G + +++ T Y+++G +L++EIA+++G+++ + + F +
Sbjct: 360 GMEYIQEVIEKALSEGRKTLTGKEVFTAYDTYGFPVDLIQEIAKEKGLEIDL-EGFQCEL 418
Query: 490 AKEAEKEKEEKEEEVVDFELV----KDLPET-RTLYYEDPFMKEFEARVLRVI-GDWIV- 542
++ E+ ++ + E + + V K+L T R + YE E+E VL +I GD IV
Sbjct: 419 EEQRERARKSFKIETKEVKPVYAHLKELGITSRFVGYEH---LEYETEVLGIIVGDEIVS 475
Query: 543 -----------LDQTAFYPEGGGQPYDTGVLFVNGSEVKVTNVQK--------VGKVIVH 583
L +T FYPEGGGQ D+G++ + KV + Q+ +GK++
Sbjct: 476 EIKEGEEGEIILRETPFYPEGGGQIGDSGIIETDKGIFKVEDTQRPTEGIIVHIGKLLKG 535
Query: 584 KVENPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTTDWA 643
K+ + V R+D +RR MR+HT TH+L AL +LG+HV QAGS + +
Sbjct: 536 KISVKDI------VHARVDKERRWDIMRNHTATHLLHAALRNLLGEHVRQAGSLVADKYL 589
Query: 644 RLDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFRLYQGGVVPGRV 703
R D +H+ +++EE++ IE L N + E+ V+ + EA Q +++ G
Sbjct: 590 RFDFTHFSPLTEEEIKRIEELVNEKIRENLPVSVMEMAYQEALQTGAIAIFEEKY--GER 647
Query: 704 IRVVKIEDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGEAAIKEWQKERE 763
+RV+ ++ + CGGTH+ +TG +G KI+ + GV RI+ G A+ +E
Sbjct: 648 VRVISCGEFSKELCGGTHVSATGDIGYFKIISESSVGAGVRRIVAQTGRWAVNTAFEEHT 707
Query: 764 ILKKASQVLRVPPEKLPETAERFFNEWKEARKEVEKLKKELAKLLVYELEAKVQKVKEYE 823
LKK S L V +++ + E E KE KE++KL++E+ KL + E KV++ + E
Sbjct: 708 TLKKVSNALGVKEDEVVQKVEELKEEIKEKEKEIQKLRQEILKLQIRE---KVKEERHRE 764
Query: 824 ---FIGEIVEGSMDDLREAVERLK-KPNRIVVLVS--KEG----YFAISVGDNVNLNAND 873
+ G + ++LR + L+ + + VV ++ KEG A S G + + AN+
Sbjct: 765 LTLYYGVFEDVEPEELRNLADILRQRTGKDVVFIASKKEGKINFVIASSKGISKEVRANE 824
Query: 874 LAKKLTSIAGGGGGGRKDVAQGRIKDVSKAKEAIESIVKLL 914
L +++ + GGGGGR+D+AQG K K E+++ + +LL
Sbjct: 825 LIRQVGKVLKGGGGGREDLAQGGGKAPDKFDESVKLLKELL 865
>dbj|BAB04986.1| (AP001511) alanyl-tRNA synthetase [Bacillus halodurans]
Length = 879
Score = 313 bits (793), Expect = 6e-84
Identities = 254/938 (27%), Positives = 440/938 (46%), Gaps = 150/938 (15%)
Query: 55 KKYTLDEMREKFLKFFEK--HEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGE 112
K T ++R+ FL FF++ H+V P + +P +L + + + + + G
Sbjct: 2 KYLTSAQVRQMFLDFFKEKGHDVEPSASL-----VPHDDPSLLWINSGVATLKKY-FDGR 55
Query: 113 ADPPANPLVISQPSIRFTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFE 172
P + +Q SIR DI+NVG T RH T FEM+ + + Y+ +E +E A+E
Sbjct: 56 VIPENPRITNAQKSIRTNDIENVGKTARHHTFFEMLGNFSIGD-----YFKEEAIEWAWE 110
Query: 173 FFTKE-----------LKMKPED------------------ITFKENPW-AGGGNAGPAF 202
F T E + + PED I + N W G G +GP
Sbjct: 111 FLTSEKWIGFDKEKLSVTVHPEDDEAYSYWKEKIGIPEERIIRLEGNFWDIGEGPSGPNT 170
Query: 203 EVLY----------------------RGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYV 240
E+ Y R LEV LVF Q+ P+ + Y
Sbjct: 171 EIFYDRGPEYGDQPNDPELYPGGENDRYLEVWNLVFSQFNHNPDGS------------YT 218
Query: 241 PMETKVVDTGYGLERLVWMSQGTPTAYDAVLGY-VVEPLKRMAGVEKIDERILMENSRLA 299
P+ K +DTG GLER+V + Q PT ++ L ++ ++++G E
Sbjct: 219 PLPKKNIDTGMGLERMVSVIQNVPTNFETDLFMPIIRATEKISGTEYGSHH--------- 269
Query: 300 GMFDIEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPS 359
V+ KV IADH + +TF + DG +PS
Sbjct: 270 --------------EADVSFKV-------------------IADHIRTVTFAIGDGALPS 296
Query: 360 NVKAGYLARLLIRKSIRHLKELGLEVP-LSEIVALHIKELHKTFPEFKEMEDVILEIIDL 418
N GY+ R L+R+++R+ K++G++ P + E+V + + +PE KE I +++
Sbjct: 297 NEGRGYVLRRLLRRAVRYAKQIGIDRPFMYELVPVVGDIMVDFYPEVKEKAAFIQKVVKT 356
Query: 419 EEKKYSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIK 478
EE+++ ETL G ++ + I K K +G S I + Y+++G +L +E E++G++
Sbjct: 357 EEERFHETLNEGLSILEKVIDKAKSEGASTISGSDVFRLYDTYGFPVDLTEEYVEEQGLQ 416
Query: 479 VHVPDNFYSIVAKEAEKEKEEKEE----EVVDFELVKDLPETRTLYYEDPFMKE-FEARV 533
V + D F + + ++ E+ + +++ +V D L + ++ + Y+ + E V
Sbjct: 417 VDL-DGFEAEMERQRERARTARQQAGSMQVQDEVLGQITVDSTFIGYKQLSTETTIETIV 475
Query: 534 L-RVIGDWI--------VLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTNVQKV--GKVIV 582
L + + D++ +L +T FY E GGQ D G++ V++VQK G+ +
Sbjct: 476 LDKTVADYVGAGQEAKVILKETPFYAESGGQVADKGIIRGANGFAVVSDVQKAPNGQHLH 535
Query: 583 HKVENPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTTDW 642
+ G + +V+ ++ R +++HT TH+L AL VLG+HV QAGS ++ +
Sbjct: 536 TVIVKEGTLQVNDQVQAIVEETERSGIVKNHTATHLLHRALKDVLGEHVNQAGSLVSEER 595
Query: 643 ARLDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFRLYQGGVVPGR 702
R D SH+ +++DEE +IER+ N + + KV EA+ L+ G G
Sbjct: 596 LRFDFSHFGQVTDEEKEKIERIVNEKIWQAIKVNISTKTLDEAKAIGAMALF--GEKYGD 653
Query: 703 VIRVVKIEDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGEAAIKEWQKER 762
++RVV++ D+ ++ CGG H+ +T +G KI+ I GV RI G+ A K+
Sbjct: 654 IVRVVEVGDYSIELCGGCHVTNTSEIGLFKIVSESGIGAGVRRIEAVTGKEAFLFMAKQL 713
Query: 763 EILKKASQVLRVPPEK-LPETAERFFNEWKEARKEVEKLKKELAKLLVYELEAKVQKVKE 821
++LK+ + ++ K +P E + +E ++E E L +L + L +VQK++
Sbjct: 714 DLLKETAATVKAKNVKDVPVRVEALQQQIRELQRENESLNAKLGNMEAGSLVNEVQKIEG 773
Query: 822 YEFIGEIVEGS-MDDLREAVERLKK--PNRIVVL-VSKEGYFAISVG-----DNVNLNAN 872
+ + + G+ MD LR V++LK+ P+ ++VL + EG I G N +A
Sbjct: 774 VPVLAKAISGADMDGLRSIVDKLKQEIPSVVIVLGTASEGKVNIVAGVTKDLINKGYHAG 833
Query: 873 DLAKKLTSIAGGGGGGRKDVAQGRIKDVSKAKEAIESI 910
L K++ + GGGGGGR D+AQ K K ++A+ +
Sbjct: 834 KLVKEVATRCGGGGGGRPDMAQAGGKQPEKLQDALSFV 871
>sp|O34526|SYA_BACSU ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|7437617|pir||A69584 alanine--tRNA ligase (EC
6.1.1.7) alaS - Bacillus subtilis
>gi|2635186|emb|CAB14682.1| (Z99117) alanyl-tRNA
synthetase [Bacillus subtilis]
>gi|2635204|emb|CAB14699.1| (Z99118) alanyl-tRNA
synthetase [Bacillus subtilis]
Length = 878
Score = 312 bits (790), Expect = 1e-83
Identities = 263/936 (28%), Positives = 431/936 (45%), Gaps = 147/936 (15%)
Query: 55 KKYTLDEMREKFLKFFEK--HEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGE 112
K T E+R+ FL FF++ H V P + +P +L + + + + + G
Sbjct: 2 KHLTSAEVRQMFLDFFKEKGHAVEPSASL-----VPHEDPSLLWINSGVATLKKY-FDGR 55
Query: 113 ADPPANPLVISQPSIRFTDIDNVGITGRHFTIFEMMAHHAFN--YPGKPIYWIDETV--- 167
P +V +Q +IR DI+NVG T RH T FEM+ + + + + I W E +
Sbjct: 56 VVPENPRIVNAQKAIRTNDIENVGKTARHHTFFEMLGNFSIGDYFKEEAITWAWEFLTSD 115
Query: 168 ------------------ELAFEFFTKELKMKPEDITFKE-NPW-AGGGNAGPAFEVLY- 206
E A+EF+ K++ + E I E N W G G +GP E+ Y
Sbjct: 116 KWIGFDKELLSVTVHPEDEEAYEFWAKKIGIPEERIIRLEGNFWDIGEGPSGPNTEIFYD 175
Query: 207 ---------------------RGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYVPMETK 245
R LEV LVF ++ P+ Y P+ K
Sbjct: 176 RGEAYGNDPEDPELYPGGENDRYLEVWNLVFSEFNHNPDGT------------YTPLPKK 223
Query: 246 VVDTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSRLAGMFDIE 305
+DTG GLER+V + Q PT +D L + K E I E G +++
Sbjct: 224 NIDTGMGLERMVSVIQNVPTNFDTDL---------FVPIIKATESISGETY---GKDNVK 271
Query: 306 DMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSNVKAGY 365
D A KV IADH + + F ++DG +PSN GY
Sbjct: 272 D----------TAFKV-------------------IADHIRTVAFAVSDGALPSNEGRGY 302
Query: 366 LARLLIRKSIRHLKELGLEVP-LSEIVALHIKELHKTFPEFKEMEDVILEIIDLEEKKYS 424
+ R L+R+++R+ K + + P + ++V + + + +PE KE D I ++I EE+++
Sbjct: 303 VLRRLLRRAVRYAKTINIHRPFMFDLVPVVAEIMADFYPEVKEKADFIAKVIKTEEERFH 362
Query: 425 ETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKVHVPDN 484
ETL G ++ I K K KG S I + Y+++G EL +E AE E + V +
Sbjct: 363 ETLNEGLAILSEMIKKEKDKGSSVISGADVFKLYDTYGFPVELTEEYAEDENMTVD-HEG 421
Query: 485 FYSIVAKEAEKEKEEKEE---EVVDFELVKDLPETRTLYYEDPFMKEFEARVLRVIGD-- 539
F + ++ E+ + +++ V ++D+ T + + +A ++ ++ D
Sbjct: 422 FEEEMNQQRERARNARQDVGSMQVQGGALRDVTVEST--FVGYSQTKADANIIVLLQDGQ 479
Query: 540 -----------WIVLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTNVQKV--GKVIVHKVE 586
I+LD+T FY E GGQ D G L + V++ +VQK G+ + V
Sbjct: 480 LIEEAHEGESVQIILDETPFYAESGGQIGDKGYLRSEQAVVRIKDVQKAPNGQHVHEGVV 539
Query: 587 NPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTTDWARLD 646
G ++G+ V ++ R +++HT TH+L AL VLG HV QAGS +T + R D
Sbjct: 540 ESGTVQKGLHVTAEVEDHMRSGVIKNHTATHLLHQALKDVLGTHVNQAGSLVTENRLRFD 599
Query: 647 ISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFRLYQGGVVPGRVIRV 706
SH+ +++ EEL +IER+ N + V+ + P EA++ L+ G G ++RV
Sbjct: 600 FSHFGQVTKEELEQIERIVNEKIWASIPVSIDLKPIAEAKEMGAMALF--GEKYGDIVRV 657
Query: 707 VKIEDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGEAAIKEWQKEREILK 766
V++ D+ ++ CGG H+ +T +G KI+ I G RI G+ A E + +LK
Sbjct: 658 VQVGDYSLELCGGCHVRNTAEIGLFKIVSESGIGAGTRRIEAVTGQGAYVEMNSQISVLK 717
Query: 767 KASQVLRVPPEKLPETAERFFNEWKEARKEVEKLKKELAKLLVYELEAKVQKVKEYEFI- 825
+ + L+ +++P+ E K+A++E E L LAKL E A + KVKE + +
Sbjct: 718 QTADELKTNIKEVPKRVAALQAELKDAQRENESL---LAKLGNVEAGAILSKVKEVDGVN 774
Query: 826 ---GEIVEGSMDDLREAVERLK-KPNRIVVLVSKEGYFAISVGDNV-------NLNANDL 874
++ M+ LR V+ LK K V+++ +++ V L+A L
Sbjct: 775 VLAAKVNAKDMNHLRTMVDELKAKLGSAVIVLGAVQNDKVNISAGVTKDLIEKGLHAGKL 834
Query: 875 AKKLTSIAGGGGGGRKDVAQGRIKDVSKAKEAIESI 910
K+ + GGGGGGR D+AQ K K +EA+ S+
Sbjct: 835 VKQAAEVCGGGGGGRPDMAQAGGKQPEKLEEALASV 870
>sp|Q9X1B6|SYA_THEMA ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|7437634|pir||E72259 alanine--tRNA ligase (EC
6.1.1.7) - Thermotoga maritima (strain MSB8)
>gi|4981959|gb|AAD36467.1|AE001792_7 (AE001792)
alanyl-tRNA synthetase [Thermotoga maritima]
Length = 863
Score = 300 bits (761), Expect = 4e-80
Identities = 261/934 (27%), Positives = 438/934 (45%), Gaps = 153/934 (16%)
Query: 58 TLDEMREKFLKFFEK--HEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADP 115
T +E+RE FLKFFEK H++ P + P P+ +L A ++ F+P + G+ +P
Sbjct: 5 TSEEIREAFLKFFEKKGHKILPSASL--IPDDPQ----LLFTVAGMVPFKP-IFWGKVEP 57
Query: 116 PANPLVISQPSIRFTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFEFFT 175
+ Q +R DI+NVG T RH T FEM+ + +F Y+ +E +E A+EF T
Sbjct: 58 VYTRVATCQKCLRTVDIENVGKTPRHHTFFEMLGNFSFGD-----YFKEEAIEWAWEFLT 112
Query: 176 KELKMKPEDITF-----------------------------KENPWAGGGNAGPA---FE 203
+ L + E + ++N W G GP E
Sbjct: 113 QVLGVPEEKLWVSVYEEDEEAFRIWNEKIGLPEKRILRMGKEDNFWGPAGPTGPCGPDTE 172
Query: 204 VLY---------------------RGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYVPM 242
+ Y R +E+ LVF +Y + E + P+
Sbjct: 173 IFYDTGYSKGCPEGEGCTPANSEGRFVEIWNLVFTEYYQDEEG------------KLHPL 220
Query: 243 ETKVVDTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSRLAGMF 302
K +DTG GLER M QG + +D L +P+ +++I+E L G
Sbjct: 221 PRKNIDTGAGLERFCAMMQGVYSNFDTDL---FQPI-----IKRIEE--------LTG-- 262
Query: 303 DIEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSNVK 362
VG +E EK + I IADH +A+TF++++GV PSN
Sbjct: 263 ------------------VGYKTDE-EKDVS----IRVIADHIRAITFLISEGVFPSNEG 299
Query: 363 AGYLARLLIRKSIRHLKELGLEVP-LSEIVALHIKELHKTFPEFKEMEDVILEIIDLEEK 421
GY+ R +IR+++RH LG+ P L IV ++++ K +PE E ++ E++ EE
Sbjct: 300 RGYVLRRIIRRAMRHGILLGMSEPFLYRIVDAVVEKMGKVYPEIVRGEGMVKEVLSAEEN 359
Query: 422 KYSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKVHV 481
++ +TL++G + + +KKG +I E Y+++GL EL EIA+++G++V V
Sbjct: 360 RFLKTLEQGMKVFDEIV---EKKG--KIDSEDAFRLYDTYGLPLELTLEIAKEKGVEVDV 414
Query: 482 PD-NFYSIVAKEAEKEKEEKEEEVVDFELVKDLPETRTLYYEDPFMKEFEARVLRVIGD- 539
+ N Y + + E +E ++ LP+ + E E V+ V D
Sbjct: 415 QEFNKYMEEQQRKSRAAMGDVEFARRYEYLEKLPKDFRTEFTGYEKLEDEGEVVLVARDD 474
Query: 540 -----------WIVLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTNVQKVGK-VIVHKVEN 587
+V +T FY E GGQ DTG++ + V V + + VIVH+++
Sbjct: 475 ETVEEASEGTVEVVFSRTPFYAEKGGQVSDTGMVEWRDGKALVEYVFEASEGVIVHRIKI 534
Query: 588 -PGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTTDWARLD 646
G + G +V R+D RR MR+HT TH+L AL +VLG HV QAGS + D R D
Sbjct: 535 LDGTLRRGQKVILRVDKKRREATMRNHTATHLLHAALKKVLGDHVRQAGSLVAPDRLRFD 594
Query: 647 ISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFRLYQGGVVPGRVIRV 706
+H+K +S E+ ++E L N +ME V + EA + L+ G V+RV
Sbjct: 595 FTHFKGLSSAEIEQVEDLVNEWIMEAIPVEVRYTSYEEAVKSGVVALFTEKY--GDVVRV 652
Query: 707 VKIEDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGEAAIKEWQKEREILK 766
V++ + CGGTH+ +TG +G KI+ E + GV RI G +A++ + +++++
Sbjct: 653 VEVPGVSKELCGGTHVKNTGQIGLFKIISEESVSSGVRRIEAVTGFSALELLRNQKKLID 712
Query: 767 KASQVLRVPPEKLPETAERFFNEWKEARKEVEKLKKELAKLLVYELEAKVQKVKEYEFIG 826
+ ++L ++L + + KE K++ + + ++ + +LE VK + +
Sbjct: 713 QLKEILGAREDELTDRVLSLREKVKELEKKLSQGRISEERIAMKQLE---DGVKVFHGVF 769
Query: 827 EIVEGS-MDDLREAVERLKKPNRIVVLVSK---EGYFAISVGDNV--NLNANDLAKKLTS 880
E VE + + + V + K+ IV+L SK + + V +N+ +A+ +A+ +
Sbjct: 770 EGVEAKHLGGIADNVLK-KEGEGIVILFSKFENKVSLVVKVSENLLGKYDASSIARNIAK 828
Query: 881 IAGGGGGGRKDVAQGRIKDVSKAKEAIESIVKLL 914
GG GGGRK+ AQ + + K+ +E + + L
Sbjct: 829 ELGGNGGGRKNFAQAGGRHPERIKDVLERLEEFL 862
>sp|P74423|SYA_SYNY3 ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|7437614|pir||S76394 hypothetical protein -
Synechocystis sp. (strain PCC 6803)
>gi|1653611|dbj|BAA18523.1| (D90915) alanyl-tRNA
synthetase [Synechocystis sp.]
Length = 877
Score = 293 bits (741), Expect = 8e-78
Identities = 257/935 (27%), Positives = 419/935 (44%), Gaps = 155/935 (16%)
Query: 61 EMREKFLKFF--EKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPAN 118
E+R++FL FF +H++ P + P P VLL A ++ F+P + G+
Sbjct: 12 EIRQQFLNFFADRQHQILPSASL--VPEDPT----VLLTIAGMLPFKP-IFLGQKSAEFP 64
Query: 119 PLVISQPSIRFTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFEFFTKEL 178
SQ IR DI+NVG T RH T FEM+ + +F Y+ + + A+E T+
Sbjct: 65 RATTSQKCIRTNDIENVGRTARHHTFFEMLGNFSFGD-----YFKSQAIAWAWELSTQVF 119
Query: 179 KMKPEDITFK-----------------------------ENPWAGG--GNAGPAFEVLY- 206
K+ E + +N W G G GP E+ Y
Sbjct: 120 KLPAERLVVSVFEEDDEAFAIWRDEIGIPAHRIQRMGADDNFWVSGPTGPCGPCSEIYYD 179
Query: 207 ----------------RGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYVPMETKVVDTG 250
R +E LVFMQY + +NA P+E K +DTG
Sbjct: 180 FHPELGDEKLDLEDDSRFIEFYNLVFMQYNR--DNA----------GNLTPLEKKNIDTG 227
Query: 251 YGLERLVWMSQGTPTAYDAVLGY-VVEPLKRMAGVEKIDERILMENSRLAGMFDIEDMGD 309
GLER+ + Q P Y+ L + +++ +AG++
Sbjct: 228 MGLERMAQILQKVPNNYETDLIFPIIQTAANIAGIDYAQAN------------------- 268
Query: 310 LKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSNVKAGYLARL 369
EK +S++ I DH +++ M+ADG+ SN+ GY+ R
Sbjct: 269 ---------EKTKVSLK-------------VIGDHVRSVVHMIADGISASNLGRGYVLRR 306
Query: 370 LIRKSIRHLKELGLEVPLS-EIVALHIKELHKTFPEFKEMEDVILEIIDLEEKKYSETLK 428
LIR+ +RH + LG+ + ++ A ++ +P E + +I + + EE + +TL+
Sbjct: 307 LIRRVVRHGRLLGINGEFTTKVAATAVQLAQPVYPNVLERQSLIEQELQREEAAFLKTLE 366
Query: 429 RGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKVHVPDNFYSI 488
RG L +A L G++EI T Y++ G EL +EIAE++GI V V + F
Sbjct: 367 RGEKL----LADLMADGVTEIAGADAFTLYDTFGFPLELTQEIAEEQGITVDV-EGFEKA 421
Query: 489 VAKEAEKEKEEKE------EEVVDFELVKDLPETRTLYYEDPFMKEFEARVL-------- 534
+ ++ E+ K E +E +D +L + T L Y D VL
Sbjct: 422 MQEQQERSKAAHETIDLTVQESLD-KLANHIHPTEFLGYTDLQSSAIVKAVLVGGELVDQ 480
Query: 535 RVIGDW--IVLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTNVQKVGKVIVH--KVENPGL 590
V G IVLDQT FY E GGQ D G L + +++ +V++ + +H +VE G
Sbjct: 481 AVAGQTVQIVLDQTPFYGESGGQIGDKGFLNGDNLLIRIEDVKRESGIFIHFGRVER-GT 539
Query: 591 FKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTTDWARLDISHY 650
+ G + ID R + +HT TH+L AL RV+ + + QAGS + + R D +
Sbjct: 540 VQIGTTITATIDRACRRRAQANHTATHLLQSALKRVVDEGISQAGSLVDFNRLRFDFNSP 599
Query: 651 KRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFRLYQGGVVPGRVIRVVKIE 710
+ ++ EEL++IE L N+ + E + +P +A+ + ++ G G +RV+ +
Sbjct: 600 RAVTMEELQQIEDLINQWIAEAHQTEVAVMPIADAKAKGAIAMF--GEKYGAEVRVIDVP 657
Query: 711 DWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGEAAIKEWQKEREILKKASQ 770
++ CGGTH+ +T +G KI+ I GV RI G + + ++K+
Sbjct: 658 GVSLELCGGTHVANTAEIGLFKIVAETGIAAGVRRIEAVAGPSVLDYLNVREAVVKELGD 717
Query: 771 VLRVPPEKLPETAERFFNEWKEARKEVEKLKKELAKLLVYELEAKVQKVKEYE-FIGEIV 829
L+ PE++P+ + E K ++K++E LK+ELA +L + Q V E++ + ++
Sbjct: 718 RLKAKPEEIPDRVHQLQQELKASQKQLEALKQELALQKSEQLLTQAQTVGEFKILVADLG 777
Query: 830 EGSMDDLREAVERL--KKPNRIVVLVS--KEG------YFAISVGDNVNLNANDLAKKLT 879
+ L+ A ERL K VVL S +EG F+ + L A +
Sbjct: 778 TVDGESLKTAAERLQQKLGESAVVLASIPEEGKVSLVAAFSPQLVKTKQLKAGQFIGAIA 837
Query: 880 SIAGGGGGGRKDVAQGRIKDVSKAKEAIESIVKLL 914
I GGGGGGR ++AQ +D SK EA+ + + L
Sbjct: 838 KICGGGGGGRPNLAQAGGRDASKLPEALATAKQTL 872
>sp|Q56273|SYA_THIFE ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|1263913|emb|CAA64818.1| (X95571) alanyl-tRNA
synthetase [Thiobacillus ferrooxidans]
Length = 877
Score = 282 bits (715), Expect = 9e-75
Identities = 254/918 (27%), Positives = 410/918 (43%), Gaps = 156/918 (16%)
Query: 62 MREKFLKFF--EKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPANP 119
+R+ FL++F + H++ P P++PR +L A ++ F+ V G P
Sbjct: 6 IRQAFLEYFVEQGHQIVPSS-----PLIPRNDPTLLFTNAGMVPFKD-VFLGLETRPYRR 59
Query: 120 LVISQPSIR----FTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFEFFT 175
V SQ +R D++NVG T RH T FEM+ + +F Y+ E + A+ F T
Sbjct: 60 AVSSQRCMRAGGKHNDLENVGYTARHHTFFEMLGNFSFGD-----YFKREVIGFAWRFLT 114
Query: 176 KELKMKPEDITF-----------------------------KENPWAGG--GNAGPAFEV 204
+ L + PE + K+N W+ G G GP E+
Sbjct: 115 ERLGLPPEKLWITVYEEDDEAADIWMNEIGVDPARLSRCGEKDNFWSMGDTGPCGPCSEI 174
Query: 205 LY-------------------RGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYVPMETK 245
Y R +E+ LVFMQ+ + P+
Sbjct: 175 FYDHGPHIPGGPPGSPEEDGDRYIEIWNLVFMQFDRDSSGT------------LTPLPKP 222
Query: 246 VVDTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSRLAGMFDIE 305
VDTG GLERL + QG YD L +PL A ++G
Sbjct: 223 SVDTGMGLERLAAVLQGVHNNYDTDL---FKPLIAAAAA-------------ISG----- 261
Query: 306 DMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSNVKAGY 365
K A + + V +ADH +A +F++ DGV+P+N GY
Sbjct: 262 -----KTYGSDAATDISLRV---------------LADHIRACSFLITDGVLPANEGRGY 301
Query: 366 LARLLIRKSIRHLKELGLE-VPLSEIVALHIKELHKTFPEFKEMEDVILEIIDLEEKKYS 424
+ R +IR+++RH ++LG+E V ++VA + E+ FPE + + ++ EE ++
Sbjct: 302 VLRRIIRRAVRHGRKLGMETVFFHQLVAPLVAEMGSAFPELTRAQREVERALEREETRFR 361
Query: 425 ETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKVHVPDN 484
ETL+RG L+ IA L + IP E + ++ G +L +IA + + + + +
Sbjct: 362 ETLERGLSLLEEAIADLAAG--AAIPGEIIFRLADTFGFPVDLTADIARERDLIMDM-EG 418
Query: 485 FYSIVAKEAEK------EKEEKEEEVVDFELVKDLPETRTLYYED--------PFMKEFE 530
+ + +A E E + E V +L LP T Y +++ E
Sbjct: 419 YEAAMADERSPLPCRLGGSGEVKTERVYHDLAMRLPVTEFTGYSTCADEGKVVALIRDGE 478
Query: 531 ARVLRVIGDW--IVLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTNVQK-VGKVIVH--KV 585
GD ++LD+T FY E GGQ D G L N + VT+ QK +G + VH +V
Sbjct: 479 EVAFLEAGDMGVVILDRTPFYGESGGQAGDRGELQSNDALFAVTDTQKPMGHLHVHLGRV 538
Query: 586 ENPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTTDWARL 645
E+ G + G V +D R HH+ TH+L AL +LG HV Q GS + + R
Sbjct: 539 ES-GRLQIGDMVVASVDEVARRATAAHHSATHLLHAALRNILGSHVQQKGSLVNPERLRF 597
Query: 646 DISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFRLYQGGVVPGRVIR 705
D SH + ++ +LREIER+ N + + LP EA+ L+ G G +R
Sbjct: 598 DFSHPEPVTAAQLREIERVVNAAIRNNVGAETRILPVAEAQALGAMALF--GEKYGDEVR 655
Query: 706 VVKIEDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGEAAIKEWQKEREIL 765
VV++ D+ ++ CGGTH+ + G +G KIL + G+ RI G A++ Q++ E L
Sbjct: 656 VVRMGDFSMELCGGTHVEALGDIGVFKILSESGVAAGIRRIEAVTGAVALEAIQRDEERL 715
Query: 766 KKASQVLRVPPEKLPETAERFFNEWKEARKEVEKLKKELAKLLVYELEAKVQKVKEYEFI 825
+ A+ +L+V P +L + + ++ KE+EK+K++ A L A+ + V +
Sbjct: 716 QAAAGLLKVAPAELDQRLAQTLERLRQLEKELEKVKRDEAVRAGAGLAAEAEDVGGVPVL 775
Query: 826 GEIVEGSMDD--LREAVERLKK--PNRIVVLVSKEG-----YFAISVGDNVNLNANDLAK 876
+EG MD LR+A++RL+ P+ ++VL E + G ++A +L
Sbjct: 776 IRRLEG-MDGKALRDALDRLRSQLPDGVIVLAGVEREKVALIAGVGKGLTGRVHAGELVN 834
Query: 877 KLTSIAGGGGGGRKDVAQ 894
+ GG GGGR ++AQ
Sbjct: 835 TVAQPLGGKGGGRPELAQ 852
>sp|P74941|SYA_THETH ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|1565288|emb|CAA69650.1| (Y08363) alanyl-tRNA
synthatase [Thermus thermophilus]
Length = 882
Score = 280 bits (710), Expect = 3e-74
Identities = 276/954 (28%), Positives = 407/954 (41%), Gaps = 180/954 (18%)
Query: 61 EMREKFLKFFEKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGE---ADPPA 117
E+REKFL FFE H R+ + ++P +L A + +P+ + +
Sbjct: 5 EIREKFLSFFEGKG---HLRLPSFSLIPEDDPSLLFTSAGMAPLKPYFLGAKPIFGGREW 61
Query: 118 NPLVISQPSIRFTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFEFFTKE 177
+ Q +R DI+NVG T RH T FEM+ + +F Y+ E + A+EF T+
Sbjct: 62 RRVTTCQECLRVGDIENVGRTSRHNTYFEMLGNFSFGD-----YFKKEAILWAWEFLTEH 116
Query: 178 LKMKP----------EDITFK-------------------ENPWAGG-------GNAGPA 201
LK+ P +D ++ EN W GG G +GP
Sbjct: 117 LKLDPGRLWVTVFEDDDEAYEIWRDLVGVPEERIGRFGEDENYWPGGAITHGPNGPSGPC 176
Query: 202 FEVLY--------------------RGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYVP 241
E Y R +E+ LVF QY + AP I+K P
Sbjct: 177 SETFYDRGPAYGTPDETGPNTGSGDRFVEIWNLVFTQYDR---QAPIPGPGILK-----P 228
Query: 242 METKVVDTGYGLERLVWMSQGTPTAYDAVLGY-VVEPLKRMAGVEKIDERILMENSRLAG 300
+ K +DTG GL R+ + Q Y + +++ + RM+G
Sbjct: 229 LPQKNIDTGMGLYRVAAILQDVEDFYRTDTFFPIIQEVARMSG----------------- 271
Query: 301 MFDIEDMGDLKLLRKKVAEKVGISVEELEKAIRPYE-----LIYAIADHTKALTFMLADG 355
RPYE IADH +A+ L+DG
Sbjct: 272 --------------------------------RPYEGKTSVSHRVIADHVRAVVAALSDG 299
Query: 356 VIPSNVKAGYLARLLIRKSIRHLKELGLEVPLSEIVALHIKELHKTF-PEFKEMEDVILE 414
SN GY+ R L+R+++RH LGL P +A + EL F PE +E + +
Sbjct: 300 ATFSNTGRGYVIRRLLRRALRHGYLLGLSDPFLHRLAPLVAELLGDFYPEMRENLPAVEK 359
Query: 415 IIDLEEKKYSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEK 474
I LEE+++ ETL+ G + ++ LK + +P ++ Y+++G +L EIA +
Sbjct: 360 QIRLEEERFLETLEGGLKRLDALLSGLKPGEV--LPGKEAFRLYDTYGFPLDLTVEIAAE 417
Query: 475 EGIKVHVP--------DNFYSIVAKEAEKEKEEKEEEVVDFELVKDLPETRTLYYEDPFM 526
G V S A E+E +K +V++ EL + T L Y
Sbjct: 418 RGYGVDTEGFQKAMEEQQSRSRAAMAFEREIFKKGAQVLE-ELYAERGATEFLGYN---A 473
Query: 527 KEFEARVLRVI-GDW------------IVLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTN 573
E EA VL ++ GD +VLD+T FY EGGGQ D G+L G +V
Sbjct: 474 LEAEAEVLALLAGDQSLLEAGPGTEVQVVLDKTPFYAEGGGQIGDFGLLEWPGGRARVET 533
Query: 574 VQKVGK-VIVHKVE-NPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHV 631
+K + + +HK G+ + G VR +D RR R+HT TH+L AL VLG HV
Sbjct: 534 TRKTERGIFLHKARVEEGVLRVGERVRAVVD-PRRRDTERNHTATHLLHAALRAVLGPHV 592
Query: 632 WQAGSQLTTDWARLDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGF 691
QAGS + D R D +H + + EEL +E L NR +M D VTW ++P EA +
Sbjct: 593 RQAGSLVAPDRLRFDFTHPEPLKPEELERVELLVNRWIMADFPVTWRYMPLEEARKEGAM 652
Query: 692 RLYQGGVVPGRVIRVVKIEDWDVQA------CGGTHLPSTGLVGPIKILRTERIQDGVER 745
L+ G G V+RVV++E ++ CGG H+ TG +G I E + GV R
Sbjct: 653 ALF--GEKYGEVVRVVRVEGSPLEGLESKELCGGCHVRRTGEIGAFLIRSEEAVSAGVRR 710
Query: 746 IIFACGEAAIKEWQKEREILKKASQVLRVPPEKLPETAERFFNEWKEARKEVEKLKKELA 805
I GE AI+ + LK ++ L V L E E+ E KE +EVE LK L
Sbjct: 711 IEAVTGEEAIRFARGSLNRLKALAERLEVGEAALEERLEKLLAELKEKEREVESLKARLV 770
Query: 806 KLLV-----YELEAKVQKVKEYEFIGEIVEGSMDDLREAVERLKKPNRIVVLVSKEGYFA 860
+ + LE +K + E+ LR+A + L V LV G
Sbjct: 771 QAALGGGGGASLE---EKGGLRWTVAELPGLDAKALRQAADDLVARGADVALVLSGGQAV 827
Query: 861 ISV---GDNVNLNANDLAKKLTSIAGGGGGGRKDVAQGRIKDVSKAKEAIESIV 911
+ + + L A L + L AGG GGG+ +AQG D KA+EA+ ++
Sbjct: 828 LKLSPKAQGMGLEAGALFRALAEKAGGRGGGKGALAQGGGLDPRKAREALPGLL 881
>sp|P27866|SYA_RHIME ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
Length = 887
Score = 276 bits (699), Expect = 7e-73
Identities = 256/953 (26%), Positives = 421/953 (43%), Gaps = 168/953 (17%)
Query: 59 LDEMREKFLKFFEKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPAN 118
++E+R FL +F K+ H V P++PR ++ A ++ F+ V +G P +
Sbjct: 4 VNEIRSMFLDYFRKNG---HEIVSSSPLVPRNDPTLMFTNAGMVQFKN-VFTGLEQRPYS 59
Query: 119 PLVISQPSIR----FTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFEFF 174
+Q +R D+DNVG T RH T FEM+ + +F Y+ + +ELA+
Sbjct: 60 TAATAQKCVRAGGKHNDLDNVGYTARHHTFFEMLGNFSFGD-----YFKERAIELAWNLI 114
Query: 175 TKELKMKPED-----------------------------ITFKENPWAGG--GNAGPAFE 203
TKE + + I +N WA G G GP E
Sbjct: 115 TKEYGLDAKRLLVTVYHTDDEAFGLWKKIAGLSDDRIIRIATSDNFWAMGDTGPCGPCSE 174
Query: 204 VLY-------------------RGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYVPMET 244
+ Y R +E+ LVFMQY++ I K +R V +
Sbjct: 175 IFYDHGDHIWGGPPGSAEEDGDRFIEIWNLVFMQYEQ-----------ITKEER-VDLPR 222
Query: 245 KVVDTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSRLAGMFDI 304
+DTG GLER+ + QG YD L
Sbjct: 223 PSIDTGMGLERVAAVLQGQHDNYDIDL--------------------------------- 249
Query: 305 EDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSNVKAG 364
+ L E G+ E +A IADH ++ F++ADGV+PSN G
Sbjct: 250 -----FRALIAASEEATGVKAEGDRRASHR-----VIADHLRSSAFLIADGVLPSNEGRG 299
Query: 365 YLARLLIRKSIRHLKELGLEVPLS-EIVALHIKELHKTFPEFKEMEDVILEIIDLEEKKY 423
Y+ R ++R+++RH + LG PL +++ + ++ + +PE E +I E + LEE ++
Sbjct: 300 YVLRRIMRRAMRHAQLLGARDPLMWKLLPALVGQMGRAYPELVRAEALISETLKLEETRF 359
Query: 424 SETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKVHVPD 483
+TL+RG +L+ A L + + E Y+++G +L ++ +GI V
Sbjct: 360 RKTLERGLNLLAEASADLSEG--DQFNGETAFKLYDTYGFPLDLTQDALRAKGIGVDTDA 417
Query: 484 NFYSIVAKEAEKEKE-----EKEEEVVDFELVKDLPETRTLYYEDPFMKEFEARVLRVIG 538
++ ++AE E E + FEL T L Y+ + E +L ++
Sbjct: 418 FTAAMQRQKAEARANWAGSGEAATETIWFELRDKHGATDFLGYDT---ESAEGVILAIVK 474
Query: 539 DW-------------IVLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTNVQKVGK-VIVHK 584
D +VL+QT FY E GGQ DTGV+ ++ VT+ QK G+ + VH
Sbjct: 475 DGAVVESAAKGENVQLVLNQTPFYGESGGQVGDTGVITTETGKLTVTDTQKRGEGLFVHY 534
Query: 585 VE-NPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTTDWA 643
G K G +D RR + +H+ TH+L AL VLG HV Q GS + +
Sbjct: 535 CTVEEGSVKTGEAAALTVDHARRARLRANHSATHLLHEALREVLGTHVAQKGSLVAPERL 594
Query: 644 RLDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFRLYQGGVVPGRV 703
R D+SH K ++ EEL+ +E +AN I++++ V + +A L+ G G
Sbjct: 595 RFDVSHPKPMTAEELKIVEEMANEIIVQNTPVVTRLMSVDDAIAEGAMALF--GEKYGDE 652
Query: 704 IRVVKI----------EDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGEA 753
+RVV + + + V+ CGGTH+ +TG +G ++++ + GV R+ GEA
Sbjct: 653 VRVVSMGQGLRGSKAGKPYSVELCGGTHVSATGDIGLVRVVSESAVGAGVRRVEALTGEA 712
Query: 754 AIKEWQKEREILKKASQVLRVPPEKLPETAERFFNEWKEARKEVEKLKKELAKLLVYELE 813
A ++ E +K + L+V P + E +E ++ +E+ + KK+LA +
Sbjct: 713 ARAYLGEQDERVKTLAAALKVQPADVLGRVEALLDERRKLERELTEAKKKLALAGDGQNG 772
Query: 814 A--KVQKVKEYEFIGEIVEG-SMDDLREAVERLKKP--NRIVVLVSKEG----YFAISVG 864
+ + + F+G +V G DL+ + KK + +V V G ++V
Sbjct: 773 SGDAARDIGGVRFLGRVVSGVEPKDLKSLADDGKKSLGSGVVAFVGVSGDGKASAVVAVT 832
Query: 865 DNV--NLNANDLAKKLTSIAGG-GGGGRKDVAQGRIKDVSKAKEAIESIVKLL 914
D++ ++A DL + ++ GG GGGGR D+AQ D +A EAIE++ L
Sbjct: 833 DDLTSKVSAVDLVRVASAALGGKGGGGRPDMAQAGGPDGGRAAEAIEAVAGAL 885
>sp|Q9ZCA4|SYA_RICPR ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|7437635|pir||H71647 alanine--tRNA ligase (EC
6.1.1.7) (alaS) RP856 - Rickettsia prowazekii
>gi|3861381|emb|CAA15280.1| (AJ235273) ALANYL-TRNA
SYNTHETASE (alaS) [Rickettsia prowazekii]
Length = 877
Score = 273 bits (692), Expect = 4e-72
Identities = 241/933 (25%), Positives = 417/933 (43%), Gaps = 162/933 (17%)
Query: 56 KYTLDEMREKFLKFFEKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADP 115
K+T +E+R KF+ +F+ + H V ++P ++ V + ++ F+ V +G+
Sbjct: 3 KFTTEEVRSKFITYFKANN---HTHVPASSLIPDNDPSLMFVNSGMVQFKN-VFTGQEKR 58
Query: 116 PANPLVISQPSIR----FTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAF 171
N V SQ S+R D+++VG T RH T FEM+ + +F Y+ ++ + +
Sbjct: 59 SYNKAVTSQKSLRAGGKHNDLEHVGYTARHHTFFEMLGNFSFGD-----YFKEQAIYYTW 113
Query: 172 EFFTKELKMKPED------------------------------ITFKENPWAGG--GNAG 199
+ TKE ++ P+D I +N W+ G G G
Sbjct: 114 DLLTKEFEL-PKDKLYVTIYHTDDPAASYWKKIAGLKDDRIIRIKTNDNFWSMGDTGPCG 172
Query: 200 PAFEVLY-------------------RGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYV 240
P E+ + R +E+ +VFMQY++ I + +
Sbjct: 173 PCSEIFFDHGEEIYGGLPGTKDENCDRFIEIWNMVFMQYEQ------------INKETRI 220
Query: 241 PMETKVVDTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSRLAG 300
+ K +DTG GLER+ + Q YD L + K+D
Sbjct: 221 ELPKKSIDTGMGLERMTAVLQHVNNNYDIDLFQEIINFTENIVKIKVD------------ 268
Query: 301 MFDIEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSN 360
G+ K + IADH +A +F++ADG+IPSN
Sbjct: 269 -------GEAKFSYR------------------------VIADHLRASSFLIADGIIPSN 297
Query: 361 VKAGYLARLLIRKSIRHLKELGLEVPLS-EIVALHIKELHKTFPEFKEMEDVILEIIDLE 419
GY+ R ++R+++RH LG + PL +++ + + +PE K E I I++ E
Sbjct: 298 EGRGYVLRRIMRRAMRHAHMLGAKEPLMYKLLPKLVDLMGNIYPELKIAESFISSILEQE 357
Query: 420 EKKYSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKV 479
E ++ TL+RG L+ E L K S++ E Y+++G +L ++I + I V
Sbjct: 358 EIRFKTTLERGLKLLTEETKTLTKG--SKLSGEVAFKLYDTYGFPLDLTEDILKNRDITV 415
Query: 480 HVPDNFYSIVAKEAEKEKE------EKEEEVVDFELVKDLPETRTLYYEDPFMKEFEARV 533
F ++ + E+ ++ E + + + F++ + T L Y + E E ++
Sbjct: 416 D-HKGFEELMLTQKERARKSWLGSGESKTDQLWFDIKEQYGSTEFLGYT---LNEAECKI 471
Query: 534 LRVIGD--------------WIVLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTNVQK-VG 578
+ +I + ++ +QT FY E GGQ D G++F GSE++V + K +
Sbjct: 472 IALIKNNNLVDNIQEINTQFLLIANQTPFYGESGGQMGDIGMIFSQGSEIEVIDTFKYLR 531
Query: 579 KVIVHK-VENPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQ 637
+IVHK + G G I+ R HH+ TH+L L ++LGK V Q GS
Sbjct: 532 SIIVHKCILKKGKINIGENANLNINIRYRQNLRIHHSATHILHAVLHKILGKQVIQKGSL 591
Query: 638 LTTDWARLDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFRLYQGG 697
+T+ + R DI+H K I+++E+ IE N I+ + +VT + +A ++ L+ G
Sbjct: 592 VTSTYLRFDINHSKAITNQEITLIEDQVNEIIRNNHEVTTTVMFTEDAIKQGAIALF--G 649
Query: 698 VVPGRVIRVVKIEDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGEAAIKE 757
+RVVKI + ++ C GTH+ TG +G KI+ I GV RI CGE IK
Sbjct: 650 EKYDSEVRVVKIGETSLELCCGTHVKRTGDIGSFKIISESAIAAGVRRIEAVCGEFVIKL 709
Query: 758 WQKEREILKKASQVLRVPPEKLPETAERFFNEWKEARKEVEKLKKELAKLLVYELEAKVQ 817
++ +LK + +L KE KE+EK L + +++ + +
Sbjct: 710 IRERDSLLKSIESSFKTNKNELITKVINILERNKELEKELEKAHLASLDLSIEQIKKQTK 769
Query: 818 KVKEYEFIGEIVEGSMDD--LREAVERL-KKPNRIVVLVSKEGYFAISVGDNVN------ 868
++ + + + V G++++ LR+A E L KK ++V+ G +S+ V+
Sbjct: 770 EITGIKLLYKEV-GNINNKILRQAAENLTKKVENLIVVYIAHGVDKLSITVAVSKAITDK 828
Query: 869 LNANDLAKKLTSIAGG-GGGGRKDVAQGRIKDV 900
NA +AK+L+ GG GGGG+ +AQ D+
Sbjct: 829 FNAGIIAKELSLFLGGSGGGGQASIAQAGGNDI 861
>dbj|BAB10601.1| (AB005243) alanyl-tRNA synthetase [Arabidopsis thaliana]
Length = 954
Score = 271 bits (686), Expect = 2e-71
Identities = 259/948 (27%), Positives = 408/948 (42%), Gaps = 164/948 (17%)
Query: 60 DEMREKFLKFFEK--HEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPA 117
D +R +FL+FF H+V P + P P VLL A ++ F+P + G+
Sbjct: 57 DSIRRRFLEFFASRGHKVLPSSSL--VPEDPT----VLLTIAGMLQFKP-IFLGKVPREV 109
Query: 118 NPLVISQPSIRFTDIDNVGITGRHFTIFEMMAHHAFN--YPGKPIYWIDE--TVEL---- 169
+Q IR D++NVG T RH T FEM+ + +F + + I W E T+E
Sbjct: 110 PCATTAQRCIRTNDLENVGKTARHHTFFEMLGNFSFGDYFKKEAIKWAWELSTIEFGLPA 169
Query: 170 -------------AFEFFTKELKMKPEDITFK---ENPWAGG--GNAGPAFEVLY----- 206
AFE + E+ + E I +N W G G GP E+ Y
Sbjct: 170 NRVWVSIYEDDDEAFEIWKNEVGVSVERIKRMGEADNFWTSGPTGPCGPCSELYYDFYPE 229
Query: 207 -------------RGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYVPMETKVVDTGYGL 253
R +E LVFMQY K + E P++ K +DTG GL
Sbjct: 230 RGYDEDVDLGDDTRFIEFYNLVFMQYNKTEDGLLE------------PLKQKNIDTGLGL 277
Query: 254 ERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSRLAGMFDIEDMGDLKLL 313
ER+ + Q P Y+ L Y +
Sbjct: 278 ERIAQILQKVPNNYETDLIYPIIA------------------------------------ 301
Query: 314 RKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSNVKAGYLARLLIRK 373
K++E IS + + + IADH +A+ ++++DGV PSN+ GY+ R LIR+
Sbjct: 302 --KISELANISYDSANDKAKTS--LKVIADHMRAVVYLISDGVSPSNIGRGYVVRRLIRR 357
Query: 374 SIRHLKELGLEVPLS--------EIVALHIKELHKTFP-EFKEMEDVILEIIDLEEKKYS 424
++R K LG+ ++ VA + EL + K I+E I EE +
Sbjct: 358 AVRKGKSLGINGDMNGNLKGAFLPAVAEKVIELSTYIDSDVKLKASRIIEEIRQEELHFK 417
Query: 425 ETLKRGSDLVRREIAKL-----KKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKV 479
+TL+RG L+ +++ K K + + Y++ G E+ E+AE+ G+ +
Sbjct: 418 KTLERGEKLLDQKLNDALSIADKTKDTPYLDGKDAFLLYDTFGFPVEITAEVAEERGVSI 477
Query: 480 HVPDNFYSIVAKEAEKEKEEKEEEVV------DFELVKDLPETRTLYYEDPFMKEFEARV 533
+ N + V E ++ + + VV D ++ K++ +T L Y D +
Sbjct: 478 DM--NGFE-VEMENQRRQSQAAHNVVKLTVEDDADMTKNIADTEFLGY-DSLSARAVVKS 533
Query: 534 LRVIGDWIV-----------LDQTAFYPEGGGQPYDTGVLFVNG------SEVKVTNVQK 576
L V G ++ LD+T FY E GGQ D G L+V+ + V+V++VQK
Sbjct: 534 LLVNGKPVIRVSEGSEVEVLLDRTPFYAESGGQIADHGFLYVSSDGNQEKAVVEVSDVQK 593
Query: 577 VGKVIVHK-VENPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAG 635
K+ VHK G + G EV +D D R + HHT TH+L AL +V+G+ QAG
Sbjct: 594 SLKIFVHKGTVKSGALEVGKEVEAAVDADLRQRAKVHHTATHLLQSALKKVVGQETSQAG 653
Query: 636 SQLTTDWARLDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFRLYQ 695
S + D R D + + + D EL EIE L NR + + ++ + LP +A++ ++
Sbjct: 654 SLVAFDRLRFDFNFNRSLHDNELEEIECLINRWIGDATRLETKVLPLADAKRAGAIAMF- 712
Query: 696 GGVVPGRVIRVVKIEDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGEAAI 755
G +RVV++ ++ CGGTH+ +T + KI+ + I G+ RI GEA I
Sbjct: 713 GEKYDENEVRVVEVPGVSMELCGGTHVGNTAEIRAFKIISEQGIASGIRRIEAVAGEAFI 772
Query: 756 KEWQKEREILKKASQVLRVPPEKLPETAERFFNEWKEARKEVEKLKKELAKLLVYELEAK 815
+ + + L+V E + E E + ARKE L+ + A + K
Sbjct: 773 EYINSRDSQMTRLCSTLKVKAEDVTNRVENLLEELRAARKEASDLRSKAAVYKASVISNK 832
Query: 816 VQKVKEYEFIGEIVEGSMDD-----LREAVER----LKKPNRIVVLVSKEG-----YFAI 861
V + I +VE SMDD L+ A E L+ P +V+ S E A
Sbjct: 833 AFTVGTSQTIRVLVE-SMDDTDADSLKSAAEHLISTLEDPVAVVLGSSPEKDKVSLVAAF 891
Query: 862 SVG-DNVNLNANDLAKKLTSIAGGGGGGRKDVAQGRIKDVSKAKEAIE 908
S G ++ + A + + GGGGGG+ + AQ + A+E
Sbjct: 892 SPGVVSLGVQAGKFIGPIAKLCGGGGGGKPNFAQAGGRKPENLPSALE 939
>pir||C81804 alanine--tRNA ligase (EC 6.1.1.7) NMA1788 [imported] - Neisseria
meningitidis (group A strain Z2491)
>gi|7380429|emb|CAB85015.1| (AL162757) alanyl-tRNA
synthetase [Neisseria meningitidis Z2491]
Length = 874
Score = 267 bits (675), Expect = 4e-70
Identities = 247/937 (26%), Positives = 403/937 (42%), Gaps = 163/937 (17%)
Query: 61 EMREKFLKFFEKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPANPL 120
E+R+KFLKFFE H V+ ++P +L A + F+ V G P +
Sbjct: 5 ELRQKFLKFFETKG---HTVVRSSSLVPHDDPTLLFTNAGMNQFKD-VFLGFDKRPYSRA 60
Query: 121 VISQPSIR----FTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFEFFTK 176
+Q +R D++NVG T RH T FEMM + +F Y+ + + A+EF T
Sbjct: 61 TTAQKCVRAGGKHNDLENVGYTARHHTFFEMMGNFSFGD-----YFKRDAIHFAWEFLTS 115
Query: 177 ----------------------------ELKMKPEDIT----------FKENPWAGG--G 196
E+ M E I +N W G G
Sbjct: 116 PEWLNIPKDKLLATVYAEDDEAYNIWLNEIGMPSERIVRIGDNKGAKYVSDNFWQMGDTG 175
Query: 197 NAGPAFEVLY-------------------RGLEVATLVFMQYKKAPENAPEDQVVIIKGD 237
GP E+ Y R +E+ VFMQ+ + +
Sbjct: 176 PCGPCSEIFYDHGEEIWGGIPGSPEEDGDRWIEIWNCVFMQFNRDEQGNMN--------- 226
Query: 238 RYVPMETKVVDTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSR 297
P+ VDTG GLER+ + Q + Y+ L
Sbjct: 227 ---PLPKPSVDTGMGLERMAAVMQHVHSNYEIDL-------------------------- 257
Query: 298 LAGMFDIEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVI 357
+ L K VA + G + E +++ IADH ++ +F++ADGV+
Sbjct: 258 ------------FQDLLKAVARETGAAFSMDEPSLK------VIADHIRSCSFLIADGVL 299
Query: 358 PSNVKAGYLARLLIRKSIRHLKELGLEVPL-SEIVALHIKELHKTFPEFKEMEDVILEII 416
PSN GY+ R +IR+++RH +LG P ++VA +KE+ +PE KE + I E +
Sbjct: 300 PSNEGRGYVLRRIIRRAVRHGYKLGQSKPFFHKLVADLVKEMGGAYPELKEKQAQIEEAL 359
Query: 417 DLEEKKYSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEG 476
EE ++++TL+ G L+ +AK G + E + Y+++G +L +I +
Sbjct: 360 KNEESRFAQTLETGMALLENALAK----GGKTLDGEIIFKLYDTYGFPYDLTADICRERN 415
Query: 477 IKVHVPDNFYSIVAKEAEKEKEEKEEEVVDFELVKDLPETRTLYYEDPFMKEFEARVLRV 536
I++ + A+ A + + + +L D +T Y + ++ E++VL +
Sbjct: 416 IELDEAGFEREMEAQRARARAAQSFK--ANAQLPYDGQDTEFKGYSE---RQTESKVLAL 470
Query: 537 IGDW-------------IVLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTNVQKVGKVIVH 583
D +V+D T FY E GGQ D G +F + + +V + QK+ +
Sbjct: 471 YKDGEQVNELNEGDSGAVVIDFTPFYAESGGQVGDVGYIFSSENRFEVRDTQKIKAAVFG 530
Query: 584 K--VENPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTTD 641
+ V+ G K G V ++D + R +MR+H+ TH++ AL VLG HV Q GS +T +
Sbjct: 531 QFGVQTSGRLKVGDSVTAKVDDEIRNANMRNHSATHLMHKALRDVLGGHVEQKGSLVTAE 590
Query: 642 WARLDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFRLYQGGVVPG 701
R DISH + ++ EE+ E+ER N V+ + V + +A++ L+ G G
Sbjct: 591 STRFDISHPQAVTAEEIAEVERRVNEAVLANVAVNAAIMSMEDAQKTGAMMLF--GEKYG 648
Query: 702 RVIRVVKIEDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGEAAIKEWQKE 761
+RV+++ + + CGGTH+ TG +G KI+ I GV RI G A+K Q++
Sbjct: 649 EEVRVLQMGGFSTELCGGTHVSRTGDIGLFKIISEGGIAAGVRRIEAITGLNALKWAQEQ 708
Query: 762 REILKKASQVLRVPPEK-LPETAERFFNEWKEARKEVEKLKKELAKLLVYELEAKVQKVK 820
++K + EK + + K KE+ + K ELA +L + +
Sbjct: 709 ERLVKDIIAETKAQTEKDVLAKIQAGAAHAKALEKELARAKAELAVHAGAKLLDDAKDLG 768
Query: 821 EYEFIGEIVEGSMDDLREAVERL--KKPNRIVVLVS-KEGYFAISVGDNVNL----NAND 873
+ + +E LRE V L K N +++L + +G ++ G + L A D
Sbjct: 769 AAKLVAAQIEADAAALREIVTDLTGKSDNAVILLAAVNDGKVSLCAGVSKPLTGKVKAGD 828
Query: 874 LAKKLTSIAGGGGGGRKDVAQGRIKDVSKAKEAIESI 910
L K GG GGGR D+AQ D K E + S+
Sbjct: 829 LVKFAAEQVGGKGGGRPDLAQAGGTDAGKLPEMLVSV 865
>pir||F81063 alanyl-tRNA synthetase NMB1595 [imported] - Neisseria meningitidis
(group B strain MD58) >gi|7226845|gb|AAF41948.1|
(AE002510) alanyl-tRNA synthetase [Neisseria
meningitidis MC58]
Length = 874
Score = 266 bits (673), Expect = 8e-70
Identities = 247/938 (26%), Positives = 402/938 (42%), Gaps = 165/938 (17%)
Query: 61 EMREKFLKFFEKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPANPL 120
E+R+KFLKFFE H V+ ++P +L A + F+ V G P +
Sbjct: 5 ELRQKFLKFFETKG---HTVVRSSSLVPHDDPTLLFTNAGMNQFKD-VFLGFDKRPYSRA 60
Query: 121 VISQPSIR----FTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFEFFTK 176
+Q +R D++NVG T RH T FEMM + +F Y+ + + A+EF T
Sbjct: 61 TTAQKCVRAGGKHNDLENVGYTARHHTFFEMMGNFSFGD-----YFKRDAIHFAWEFLTS 115
Query: 177 ----------------------------ELKMKPEDIT----------FKENPWAGG--G 196
E+ M E I +N W G G
Sbjct: 116 PEWLNIPKDKLLATVYAEDDEAYNIWLNEIGMPSERIVRIGDNKGAKYASDNFWQMGDTG 175
Query: 197 NAGPAFEVLY-------------------RGLEVATLVFMQYKKAPENAPEDQVVIIKGD 237
GP E+ Y R +E+ VFMQ+ + +
Sbjct: 176 PCGPCSEIFYDHGEEIWGGIPGSPEEDGDRWIEIWNCVFMQFNRDEQGNMN--------- 226
Query: 238 RYVPMETKVVDTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSR 297
P+ VDTG GLER+ + Q + Y+ L
Sbjct: 227 ---PLPKPSVDTGMGLERIAAVMQHVHSNYEIDL-------------------------- 257
Query: 298 LAGMFDIEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVI 357
+ L K VA + G E +++ IADH ++ +F++ADGV+
Sbjct: 258 ------------FQDLLKAVARETGAPFRMEEPSLK------VIADHIRSCSFLIADGVL 299
Query: 358 PSNVKAGYLARLLIRKSIRHLKELGLEVPL-SEIVALHIKELHKTFPEFKEMEDVILEII 416
PSN GY+ R +IR+++RH +LG P ++VA +KE+ +PE KE + I E +
Sbjct: 300 PSNEGRGYVLRRIIRRAVRHGYKLGQSKPFFHKLVADLVKEMGGAYPELKEKQAQIEEAL 359
Query: 417 DLEEKKYSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEG 476
EE ++++TL+ G L+ + K K EI + Y+++G +L +I +
Sbjct: 360 KNEESRFAQTLETGMALLENALVKGGKTLGGEI----IFKLYDTYGFPYDLTADICRERN 415
Query: 477 IKVHVPDNFYSIVAKEAEKEKEEKEEEV-VDFELVKDLPETRTLYYEDPFMKEFEARVLR 535
I+ PD EA++ + + + +L D +T Y + ++ E++VL
Sbjct: 416 IE---PDEAGFEREMEAQRARARAAQSFKANAQLPYDGQDTEFKGYSE---RQTESKVLA 469
Query: 536 VIGDW-------------IVLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTNVQKVGKVIV 582
+ D +V+D T FY E GGQ D G +F + +V + QK+ +
Sbjct: 470 LYKDGEQVNELNEGDSGAVVIDFTPFYAESGGQVGDVGYIFSGENRFEVRDTQKIKAAVF 529
Query: 583 HK--VENPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTT 640
+ V+ G K G V ++D + R +MR+H+ TH++ AL VLG+HV Q GS +T
Sbjct: 530 GQFGVQTSGRLKVGDSVTAKVDDEIRNANMRNHSATHLMHKALRDVLGRHVEQKGSLVTA 589
Query: 641 DWARLDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFRLYQGGVVP 700
+ R DISH + ++ EE+ E+ER N ++ + V + +A++ L+ G
Sbjct: 590 ESTRFDISHPQAVTAEEIAEVERRVNEAILANVAVNAAIMSMEDAQKTGAMMLF--GEKY 647
Query: 701 GRVIRVVKIEDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGEAAIKEWQK 760
G +RV+++ + + CGGTH+ TG +G KI+ I GV RI G A+K Q+
Sbjct: 648 GEEVRVLQMGGFSTELCGGTHVSRTGDIGLFKIISEGGIAAGVRRIEAITGLNALKWAQE 707
Query: 761 EREILKKASQVLRVPPEK-LPETAERFFNEWKEARKEVEKLKKELAKLLVYELEAKVQKV 819
+ ++K + EK + + K KE+ + K ELA +L + +
Sbjct: 708 QERLVKDIIAETKAQTEKDVLAKIQAGAAHAKALEKELARAKAELAVHAGAKLLDDAKDL 767
Query: 820 KEYEFIGEIVEGSMDDLREAVERL--KKPNRIVVLVS-KEGYFAISVGDNVNL----NAN 872
+ + +E LRE V L K N +++L + +G ++ G + L A
Sbjct: 768 GAAKLVAAQIEADAAALREIVTDLTGKSDNAVILLAAVNDGKVSLCAGVSKPLTGKVKAG 827
Query: 873 DLAKKLTSIAGGGGGGRKDVAQGRIKDVSKAKEAIESI 910
DL K GG GGGR D+AQ D K ++S+
Sbjct: 828 DLVKFAAEQVGGKGGGRPDLAQAGGTDADKLPAVLDSV 865
>pir||H83533 alanyl-tRNA synthetase PA0903 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9946804|gb|AAG04292.1|AE004524_9
(AE004524) alanyl-tRNA synthetase [Pseudomonas
aeruginosa]
Length = 874
Score = 264 bits (667), Expect = 4e-69
Identities = 249/926 (26%), Positives = 409/926 (43%), Gaps = 146/926 (15%)
Query: 61 EMREKFLKFFEKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPANPL 120
E+RE FL+FFE+ H RV ++P +L A + F+ + E
Sbjct: 5 EIREAFLRFFEEKG---HTRVASSSLIPANDPTLLFTNAGMNQFKDCFLGLEKRAYTRAT 61
Query: 121 VISQPSIR----FTDIDNVGITGRHFTIFEMMAHHAF----------------------N 154
SQ +R D++NVG T RH T FEM+ + +F N
Sbjct: 62 T-SQKCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKRDAIHYAWEFLTGEKWLN 120
Query: 155 YPGKPIY-WIDETVELAFEFFTKELKMKPEDIT----------FKENPWAGG--GNAGPA 201
P + ++ + T + A++ +TKE+ + E + +N WA G G GP
Sbjct: 121 LPKEKLWVTVYATDDEAYDIWTKEVGVPAERMVRIGDNKGAPYASDNFWAMGDTGPCGPC 180
Query: 202 FEVLY-------------------RGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYVPM 242
E+ + R +E+ VFMQ+ + + P+
Sbjct: 181 TEIFFDHGPEIWGGPPGSPEEDGDRYIEIWNNVFMQFNRTADGVMH------------PL 228
Query: 243 ETKVVDTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSRLAGMF 302
VDTG GLER+ + Q + Y+ ID L +N
Sbjct: 229 PAPSVDTGMGLERVSAVLQHVHSNYE------------------ID---LFQN------- 260
Query: 303 DIEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSNVK 362
L K AE +G + ++ + +ADH ++ +F++ADGV+PSN
Sbjct: 261 ----------LLKASAEAIGCANDDAPS-------LKVVADHIRSCSFLIADGVLPSNEG 303
Query: 363 AGYLARLLIRKSIRHLKELGLEVPL-SEIVALHIKELHKTFPEFKEMEDVILEIIDLEEK 421
GY+ R +IR++ RH +LG +IVA + E+ FPE K+ + I ++ EE+
Sbjct: 304 RGYVLRRIIRRACRHGNKLGARGTFFHKIVAALVAEMGDAFPELKQQQAHIERVLKTEEE 363
Query: 422 KYSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKVHV 481
++++TL++G ++ +++A+L+ S IP + Y+++G +L +IA + + +
Sbjct: 364 QFAKTLEQGLKILEQDLAELQG---SVIPGNVVFKLYDTYGFPVDLTNDIARERELTID- 419
Query: 482 PDNFYSIVAKEAEKEKEEKEEEVVDFELVKDLPETRTLYYED--------PFMKEFEARV 533
D F + + E+ + + LVK ETR L Y+ ++ +A
Sbjct: 420 EDGFEREMEAQRERARASSAFGMDYNSLVKVDGETRFLGYQGVSGAGQIVALFRDGQAVE 479
Query: 534 LRVIGDW--IVLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTNVQKVGKVIVHK-VENPGL 590
G+ +VLDQT FY E GGQ D+G L G V + K G +H V G
Sbjct: 480 RLEEGEEGVVVLDQTPFYAESGGQVGDSGYLEAAGVRFDVRDTTKAGGAHLHHGVVARGN 539
Query: 591 FKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTTDWARLDISHY 650
G V+ +D R +H+ TH+L AL +VLG HV Q GS + + R D SH+
Sbjct: 540 LSVGGAVKAEVDASVRQATALNHSATHLLHAALRQVLGDHVQQKGSLVDSQRLRFDFSHF 599
Query: 651 KRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFRLYQGGVVPGRVIRVVKI- 709
+ I E+L+ +E + N + + +V E A+ + L+ G G +RV+ +
Sbjct: 600 EAIKAEQLKALEDIVNAEIRRNTEVETEETDIDTAKAKGAMALF--GEKYGDQVRVLSMG 657
Query: 710 EDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGEAAIKEWQKEREILKKAS 769
D+ V+ CGGTH+ TG +G KI + GV RI G AA+ E LK+A+
Sbjct: 658 GDFSVELCGGTHVSRTGDIGLFKITSEGGVAAGVRRIEAVTGAAALAYLNGAEEQLKEAA 717
Query: 770 QVLRVPPEKLPETAERFFNEWKEARKEVEKLKKELAKLLVYELEAKVQKVKEYEFIGEIV 829
+++ + L + + KE+E+LK + A +L A ++K + + +
Sbjct: 718 SLVKGSRDNLLDKLGALLERNRSLEKELEQLKAKAASAAGDDLSAAAVEIKGAKVLAARL 777
Query: 830 EG-SMDDLREAVERLK-KPNRIVVLVSKE--GYFAISVGDNVN----LNANDLAKKLTSI 881
+G L V++LK K R V+L+ E G + G + L A +L K+ +
Sbjct: 778 DGLDGKALLALVDQLKNKLGRAVILLGGELDGKVVLVAGVTQDLTGQLKAGELMKQAAAA 837
Query: 882 AGGGGGGRKDVAQGRIKDVSKAKEAI 907
GG GGGR D+AQG D +K EA+
Sbjct: 838 VGGKGGGRPDMAQGGGTDAAKLDEAL 863
>gb|AAD53924.1|AF179611_8 (AF179611) alanyl-tRNA synthetase [Zymomonas mobilis]
Length = 888
Score = 263 bits (664), Expect = 9e-69
Identities = 243/956 (25%), Positives = 422/956 (43%), Gaps = 172/956 (17%)
Query: 58 TLDEMREKFLKFFEKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPA 117
T +E+R F + F K +P P++P+ ++ V A ++ F+ +G P
Sbjct: 3 TTNEIRRSFSRIFRKE--WPSDSTIA-PLVPQNDPTLMFVNAGMVPFKN-TFTGLESRPY 58
Query: 118 NPLVISQPSIR----FTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFEF 173
SQ +R D+DNVG T RH T FEM+ + +F Y+ + +ELA+
Sbjct: 59 KTATSSQKCVRAGGKHNDLDNVGYTARHHTFFEMLGNFSFGD-----YFKERVIELAWGL 113
Query: 174 FTKELKMKPE-----------------------------DITFKENPWAGG--GNAGPAF 202
TKE + PE I +N W+ G G GP
Sbjct: 114 ITKEWGLDPERLCVTVYHTDEEAFNLWRKIAGLPEDRIIKIATSDNFWSMGDTGPCGPCS 173
Query: 203 EVLY------------------RGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYVPMET 244
E+ Y R +E+ LVFMQY++ + + + +
Sbjct: 174 EIFYDHGPEIPGASGLADEDGDRFVEIWNLVFMQYEQ------------VNAETRLNLPR 221
Query: 245 KVVDTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSRLAGMFDI 304
+DTG GLER+ + QG YD + K + + ++ G F
Sbjct: 222 PSIDTGMGLERIASVLQGVHDNYDT------DTFKALIAASGE-----LTHTATDGQF-- 268
Query: 305 EDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSNVKAG 364
K + +V IADH +A F++ADGV+P+N G
Sbjct: 269 -----------KASHRV-------------------IADHLRAAGFLVADGVLPANEGRG 298
Query: 365 YLARLLIRKSIRHLKELGLEVPLS-EIVALHIKELHKTFPEFKEMEDVILEIIDLEEKKY 423
Y+ R ++R+++RH +G + PL +V + E+ +PE + +I E + LEE ++
Sbjct: 299 YVLRRIMRRAMRHAHLIGAKEPLMYRLVPALLSEMGMAYPELVRAKALIEETLRLEETRF 358
Query: 424 SETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKVHVPD 483
+TL G +++ E LK +P Y+++G +L + + V
Sbjct: 359 RQTLANGLKILKDETQHLKSG--DTLPGAVAFRLYDTYGFPYDLTADALRARNLTVDQAG 416
Query: 484 NFYSIV-----AKEAEKEKEEKEEEVVDFELVKDLPETRTLYYEDPFMKEFEARVLRVIG 538
++ A+ A K EK + + F++ L T Y ++ +++ +I
Sbjct: 417 FDAAMAEQRKAARAAWKGSGEKASDEIWFDIADQLGGTEFTGYT---AEKGSGQIIALIK 473
Query: 539 DW-------------IVLDQTAFYPEGGGQPYDTGVLFVNGS-EVKVTNVQK-VGKVIVH 583
D I+ +QT FY E GGQ D GV+ N ++ VT+ QK +G++ H
Sbjct: 474 DGKRVETAKQGDDITIITNQTPFYGESGGQKGDIGVITGNNDLKMTVTDTQKPLGRIHAH 533
Query: 584 --KVENPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTTD 641
K+E G K G +++ ++D + R + +H+ TH+L AL LG+HV Q GS ++ +
Sbjct: 534 IAKIEK-GEIKIGDDIQLQVDINHRNRLRANHSATHLLHAALRDQLGQHVSQKGSMVSAE 592
Query: 642 WARLDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFRLYQGGVVPG 701
R D SH K +SD+EL IE N+ ++ + VT + A + L+ G G
Sbjct: 593 RLRFDFSHQKALSDQELAAIEAEVNQQILNNSVVTTRLMTPESAVEAGAMALF--GEKYG 650
Query: 702 RVIRVVKI----------EDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACG 751
+RV+ + W V+ CGGTH+ + G +G I+ + G+ RI G
Sbjct: 651 NEVRVLSMGSCLNDQNEESSWSVELCGGTHVSALGQIGLFHIVSETAVSSGIRRIEAVTG 710
Query: 752 EAAIKEWQKERE-ILKKASQVLRVPPEKLPETAERFFNEWKEARKEV---EKLKKELAKL 807
E A + W R+ +L++ + +L+ PE++P +E ++ ++ + + L A
Sbjct: 711 EEA-RLWLVGRDRLLRETASILKAVPEEVPTRTAAILDERRKCQRSLADQKALAFANANC 769
Query: 808 LVYELEAKVQKVKEYEFIGEIVEG----SMDDLREAVERLKKPNRIVVLVSKEGYFAISV 863
A K+ Y FIG+++EG ++ L + +++ + I ++ EG ++++
Sbjct: 770 GQGGNNAAPDKLGAYHFIGQVIEGLEPKALLGLIDENKKIIESGVIALITVNEGRASVAI 829
Query: 864 GDNVNL----NANDLAKKLTSIAGG-GGGGRKDVAQGRIKDVSKAKEAIESIVKLL 914
G + +L +A DL +K GG GGGGR D+AQG + ++A +A+E++ LL
Sbjct: 830 GVSDSLKGKISAVDLVRKAVETLGGKGGGGRPDMAQGGGPNGNEAAQALEAVKALL 885
>sp|P70865|SYA_BARBA ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|1568622|gb|AAB09037.1| (U68242) AlaS [Bartonella
bacilliformis]
Length = 886
Score = 260 bits (657), Expect = 6e-68
Identities = 248/949 (26%), Positives = 419/949 (44%), Gaps = 167/949 (17%)
Query: 58 TLDEMREKFLKFFEKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPA 117
+++ +R FL +F ++ H + P++PR ++ A ++DF+ V +G
Sbjct: 3 SVNNIRSTFLDYFHRNG---HEVLSSSPLVPRNDPTLMFTNAGMVDFKN-VFTGLEKHSY 58
Query: 118 NPLVISQPSIR----FTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFEF 173
N +Q +R D+DNVG T RH T FEM+ + +F+ Y+ +E + A+
Sbjct: 59 NRATTAQKCVRAGGKHNDLDNVGYTARHHTFFEMLGNFSFSN-----YFKEEAIFYAWNL 113
Query: 174 FTKELKMKPED-----------------------------ITFKENPWAGG--GNAGPAF 202
TKE + + I +N W G G GP
Sbjct: 114 LTKEFCLSKDKLLVTVYHDDDVAAGLWRKISGLSEEKIIRIATNDNFWMMGDTGPCGPCS 173
Query: 203 EVLY-------------------RGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYVPME 243
E+ Y R +E+ LVFMQY++ + ++ + +
Sbjct: 174 EIFYDHGDKIWGGPPGSADEDGDRFIEIWNLVFMQYEQ------------LSKEKRIELP 221
Query: 244 TKVVDTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSRLAGMFD 303
+DTG GLER+ + QG YD L R L+ S+ +
Sbjct: 222 QPSIDTGMGLERIAAVLQGVHDNYDIDLF-----------------RTLIHASQ--EIIG 262
Query: 304 IEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSNVKA 363
++ GD + IADH ++ F++ADG++PSN
Sbjct: 263 VKATGDFFASHR------------------------VIADHLRSSAFLIADGIMPSNEGR 298
Query: 364 GYLARLLIRKSIRHLKELGL-EVPLSEIVALHIKELHKTFPEFKEMEDVILEIIDLEEKK 422
GY+ R ++R+++RH LG ++ + +V + I E+ + +PE E +I EI+ LEE +
Sbjct: 299 GYVLRRIMRRAMRHAHLLGSKDLLMWRLVPVLISEMGQAYPELVRAESLISEILKLEETR 358
Query: 423 YSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKVHVP 482
+ +TL+RG L+ L++ E Y+++G +L ++ + GI V V
Sbjct: 359 FRKTLERGLGLLNEASTHLEEGDYFNG--EVAFKLYDTYGFPLDLTQDALRRRGISVDVD 416
Query: 483 DNFYSIVAKEAEKEKE-----EKEEEVVDFELVKDLPETRTLYYEDPFMKEFEARVLRVI 537
++ ++AE + E V F + + T L YE ++ E + +I
Sbjct: 417 AFDKAMKRQKAEARANWSGSGDCVTETVWFSIRDQVGATEFLGYET---EKAEGIITALI 473
Query: 538 GD-------------WIVLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTNVQKVG-KVIVH 583
D IV++QT FY E GGQ D+G++ +V + QK G V +H
Sbjct: 474 RDGEVVDHIDLGQKAMIVVNQTPFYGESGGQVGDSGIISGANFIFEVHDTQKKGDNVFIH 533
Query: 584 KVE-NPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTTDW 642
E G K+ V +D RR + +H+ TH+L +L + LG HV Q GS ++ D
Sbjct: 534 IGEIKTGQAKKHDCVELIVDSARRRKIRANHSATHLLHESLRQTLGSHVVQKGSFVSPDR 593
Query: 643 ARLDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFRLYQGGVVPGR 702
R D SH K IS EEL++IE LAN IV+++ KVT + +A L+ G G
Sbjct: 594 LRFDFSHPKSISSEELKKIEDLANDIVLQNSKVTTRLMAIDDAIAEGAMALF--GEKYGD 651
Query: 703 VIRVVKIED----------WDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGE 752
+RV+ + + W ++ CGGTH+ TG +G I I+ + GV RI
Sbjct: 652 EVRVISMGNNLEQTGSKKWWSIELCGGTHVQRTGDIGLIHIISETSVAAGVRRIEALTAT 711
Query: 753 AAIKEWQKEREILKKASQVLRVPPEKLPETAERFFNEWKEARKEVEKLKKELA-KLLVYE 811
AA + + + + +L+ P + E + +E ++ KE+ +K++A
Sbjct: 712 AARLYLHGQDRRVYEIAGLLKTSPADVQERVQTLLDERRKLEKELNDSRKKIALNGGSVN 771
Query: 812 LEAKVQKVKEYEFIGEIVEGSM-DDLREAVERLKKP--NRIVVLVS----KEGYFAISVG 864
+ +Q + F+G +V + DL+ V+ KK + +V +S +G + V
Sbjct: 772 SQGDIQTINGISFMGGVVSNILPKDLKALVDSGKKKIGSGVVAFISVSEDGKGSAVVGVT 831
Query: 865 DNV--NLNANDLAKKLTSIAGG-GGGGRKDVAQGRIKDVSKAKEAIESI 910
D++ LNA DL + ++ GG GGGGR+D+AQ + KA EA+ ++
Sbjct: 832 DDLTDTLNAVDLVRIISVTLGGQGGGGRRDMAQAGGSEGGKADEALVAL 880
>sp|Q9ZJY5|SYA_HELPJ ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|7437615|pir||F71842 alanine--tRNA ligase (EC
6.1.1.7) - Helicobacter pylori (strain J99)
>gi|4155760|gb|AAD06738.1| (AE001543) ALANYL-TRNA
SYNTHETASE [Helicobacter pylori J99]
Length = 847
Score = 258 bits (652), Expect = 2e-67
Identities = 228/926 (24%), Positives = 407/926 (43%), Gaps = 172/926 (18%)
Query: 61 EMREKFLKFFEK--HEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPAN 118
++R +FL+FF+ HE+YP P++P +L A ++ F+ + +G P+
Sbjct: 2 DIRNEFLQFFQNKGHEIYPS-----MPLVPN-DATLLFTNAGMVQFKD-IFTGIVPRPSI 54
Query: 119 PLVISQPSI-----RFTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFEF 173
P S + D++NVG T RH T+FEM+ + +F Y+ +E + A+EF
Sbjct: 55 PRAASSQLCMRAGGKHNDLENVGYTARHHTLFEMLGNFSFGD-----YFKEEAILFAWEF 109
Query: 174 FTKELKMKPEDITF---------------------------KENPWAGG--GNAGPAFEV 204
TK L KP+D+ K+N W G G GP E+
Sbjct: 110 VTKNLGFKPKDLYISVHEKDDEAVKLWEKFVPVDRIKKMGDKDNFWQMGDSGPCGPCSEI 169
Query: 205 LY-------------------RGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYVPMETK 245
R LE+ LVFMQY+++ + P+
Sbjct: 170 YIDQGEKHFKGSEDYFGGEGDRFLEIWNLVFMQYERSNDGVLS------------PLPKP 217
Query: 246 VVDTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSRLAGMFDIE 305
+DTG GLER+ + + +D+ L
Sbjct: 218 SIDTGMGLERVQALLEHKLNNFDSSL---------------------------------- 243
Query: 306 DMGDLKLLRKKVAEKVGIS-VEELEKAIRPYELIYAIADHTKALTFMLADGVIPSNVKAG 364
L ++++E G+ E + + R +ADH +A+ F+LA V + G
Sbjct: 244 ----FAPLMEEISELTGLDYASEFQPSFR------VVADHARAVAFLLAQEVHFNKEGRG 293
Query: 365 YLARLLIRKSIRHLKELGL-EVPLSEIVALHIKELHKTFPEFKEMEDVILEIIDLEEKKY 423
Y+ R ++R+++RH +GL E L ++V + ++ KE ++++++ EE+++
Sbjct: 294 YVLRRILRRALRHGYLMGLKEAFLYKVVGVVCEQFSNVHAYLKESKEMVMKECFEEEERF 353
Query: 424 SETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKVHVPD 483
ETL+ G +L + L + + + + Y++ G +L ++ G V +
Sbjct: 354 LETLESGMELFNLSLTHLNENKIFDGKIA--FKLYDTFGFPLDLTNDMLRSHGACVDM-Q 410
Query: 484 NFYSIVAKEAEKEKEEKE-----------------EEVVDFELVKDLPETRTLYYEDPFM 526
F + + ++ ++ K + E V +E + L +++ F
Sbjct: 411 GFENCMQEQVKRSKASWKGKQNNADFSAILNAYAPNEFVGYETTECLANALG-FFDSDFK 469
Query: 527 KEFEARVLRVIGDWIVLDQTAFYPEGGGQPYDTGVLFVNGSEVK-VTNVQKVGKVIVHKV 585
+ EA + + W++L++T FY EGGG D G LF + E V + + + +
Sbjct: 470 EITEANPNQEV--WVLLEKTPFYAEGGGAIGDRGTLFKDNEEAALVLDTKNFFGLNFSLL 527
Query: 586 ENPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTTDWARL 645
E K+G +V ++ D R++ +HH+ TH+L AL VLG HV QAGS + + R
Sbjct: 528 EIKKALKKGDQVIAQVS-DERLEIAKHHSATHLLQSALREVLGSHVSQAGSLVESKRLRF 586
Query: 646 DISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFRLYQGGVVPGRVIR 705
D SH K ++DEEL ++E L N + + E +P +A+ + L+ +R
Sbjct: 587 DFSHAKALNDEELEKVEDLVNAQIFKHLTSQVEHMPLNQAKDKGALALFSEKYAEN--VR 644
Query: 706 VVKIEDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGEAAIKEWQKEREIL 765
VV ++ ++ CGG H+ +TGL+G +I++ + GV RI CG+A + ++E + L
Sbjct: 645 VVSFKEASIELCGGIHVENTGLIGGFRIVKESGVSSGVRRIEAVCGKAFYQLTKEENKEL 704
Query: 766 KKASQVLRVPPEKLPETAERFFNEWKEARKEVEKLKKELAKLLVYELEAKVQKVKEYEFI 825
K A +L+ N+ KE+ K +K ++ V+K+ +
Sbjct: 705 KNAKTLLK------NNDVIAGINKLKESVKNSQKAP--------VSMDLPVEKIHGVNLV 750
Query: 826 GEIVEGSMDDLREAVERLK-KPNRIVVLVSKEGYFAISVG---DNVNLNANDLAKKLTSI 881
+VE D++E ++RLK K +++ +V K+ I++ NV + AN A ++ I
Sbjct: 751 VGVVE--QGDIKEMIDRLKSKHEKLLAIVFKKENERITLACGVKNVPIKANAWANEVAQI 808
Query: 882 AGGGGGGRKDVAQGRIKDVSKAKEAI 907
GG GGGR D A KD+ + A+
Sbjct: 809 LGGKGGGRDDFASAGGKDIENLQAAL 834
>pir||F75289 alanyl-tRNA synthetase - Deinococcus radiodurans (strain R1)
>gi|6460111|gb|AAF11848.1|AE002062_1 (AE002062)
alanyl-tRNA synthetase [Deinococcus radiodurans]
Length = 890
Score = 255 bits (644), Expect = 2e-66
Identities = 265/955 (27%), Positives = 412/955 (42%), Gaps = 175/955 (18%)
Query: 58 TLDEMREKFLKFFEK--HEVYP-HGRVKRYPVLPRWRDDVLLVGASIMDFQ------PWV 108
T E+RE++L FFE H P H + P L A + F+ P V
Sbjct: 6 TTAEIRERYLYFFETKGHLRLPSHSTIAPDPT-------TLFTVAGMQPFKENFMGAPAV 58
Query: 109 ISGEADPPANPLVISQPSIRFTDIDNVGITGRHFTIFEMMAHHAFN--YPGKPIYWIDET 166
G+ P+ + +Q +R DI+NVG T RH ++FEMM + +F + I+W E
Sbjct: 59 FDGQ---PSKRVTTAQKCVRVGDIENVGRTRRHLSLFEMMGNFSFGDYFKRDAIHWAWEF 115
Query: 167 V---------------------ELAFEFFTKELKMKPEDI---TFKENPWAGG------- 195
+ + AF ++T+++ + E I EN W
Sbjct: 116 LTGPEWMGMDKDKMYVTVYKDDDEAFGYWTQDIGLPAEHIHRFDADENFWPANAPLEGPN 175
Query: 196 GNAGPAFEVLY---------------------RGLEVATLVFMQYKKAPENAPEDQVVII 234
G GP E+ Y R LEV LVF QY + +A V+
Sbjct: 176 GPCGPCSEIYYDRGENYGDDTWGDYYQTRESARFLEVWNLVFPQYDRQDLDASGQPVL-- 233
Query: 235 KGDRYVPMETKVVDTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILME 294
+ K +DTG GLER+ + Q P Y V +P+ VE++ E
Sbjct: 234 -----KDLPFKNIDTGMGLERVASVVQDVPDFYS---NDVFKPI-----VERVAE----- 275
Query: 295 NSRLAGMFDIEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLAD 354
L K + +S +A+H ++++ ++AD
Sbjct: 276 -----------------LSGKPYEGETSVSHR-------------VVAEHIRSVSMIVAD 305
Query: 355 GVIPSNVKAGYLARLLIRKSIRHLKELGLEVP-LSEIVALHIKELHKTFPEFKEMEDVIL 413
G SN GY AR ++R++IRH LGL P L +V L + + +PE + + +
Sbjct: 306 GTAFSNTGRGYTARKIMRRAIRHGYMLGLREPQLYRLVELVVDSMGGAYPELQHNQSRVE 365
Query: 414 EIIDLEEKKYSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAE 473
+ EE+++ +TL+ G + ++ ++K S + + Y+++G +L KEIAE
Sbjct: 366 ASVRAEEEQFLKTLEGGIKRLGGLLSGMEKG--STLVGKDAFELYDTYGFPVDLTKEIAE 423
Query: 474 KEGIKVHVPDNFYSIVAKEAEKEKEEKEEEVVDF----ELVKDLPETRTLYYEDPFMKEF 529
+ G+ V S+ + K + F E + LP T+ + Y+
Sbjct: 424 EYGVSVDEAGYAESLEHAQEIARAGSKYGKSELFGGHQEALDGLPATQFVGYDQT---SG 480
Query: 530 EARVLRVIGDW-------------IVLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTNVQK 576
+ +VL ++ +VL QT FY EGGG+ DTG L +G V + QK
Sbjct: 481 DGQVLALLSGGERLSHLPAGSEATVVLSQTPFYGEGGGEVGDTGRLEWDGGAGIVRDTQK 540
Query: 577 VGK-VIVHKV-ENPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQA 634
+ V +H V G KEG VRG + R RHHT TH+L AL VLG V Q
Sbjct: 541 TKQGVFLHDVLVEQGELKEGTRVRGVVS-PERAAIQRHHTATHLLHAALRAVLGGGVQQK 599
Query: 635 GSQLTTDWARLDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFRLY 694
GS++ D R D SH +S EE+ ++E L +R V + V+W +P EA+ L+
Sbjct: 600 GSRVAADQLRFDFSHGAAMSAEEIAQVETLVSRWVSANFPVSWREMPIAEAKAAGATALF 659
Query: 695 QGGVVPGRVIRVVKIE-DWD--------VQACGGTHLPSTGLVGPIKILRTERIQDGVER 745
G G V+RVV++E D D ++ CGG H+ TG +G I+ E + GV R
Sbjct: 660 --GEKYGDVVRVVRVEGDVDFGGHAVSSMELCGGAHVSRTGDIGAFVIVSDENVAAGVRR 717
Query: 746 IIFACGEAAIKEWQKEREILKKASQVLRVPPEKLPETAERFFNEWKEARKEVEKLKKELA 805
I GE A + KA+ +L PE L E + K A KE + +++LA
Sbjct: 718 IEALAGEQATAWLRGRLNASAKAAALLNTSPEGLEERVSGLQGQLKAAEKETAQARRQLA 777
Query: 806 KLLVYELEAKVQ-------KVKEYEFIGEIVEGSMDDLREAVERL--KKPNRIVVLVSKE 856
+ + + Q KV + G +EG ++LR A ++L + +VV+ S +
Sbjct: 778 EAQMGGGGSAAQTRELGGFKVASLKLSG--IEG--NELRGAADKLLDQSGADLVVIASDK 833
Query: 857 GYFAISVGDNV--NLNANDLAKKLTSIAGGGGGGRKDVAQGRIKDVSKAKEAIES 909
G + D V +A L KL + GG GGGR D+AQ I D + A A+++
Sbjct: 834 GLVVKATKDAVAKGAHAGQLVSKLAAAGGGKGGGRPDMAQAGITDAAGALGALDT 888
>emb|CAB93381.1| (AL357523) alanine tRNA synthetase [Streptomyces coelicolor A3(2)]
Length = 890
Score = 254 bits (641), Expect = 4e-66
Identities = 240/943 (25%), Positives = 416/943 (43%), Gaps = 151/943 (16%)
Query: 61 EMREKFLKFFEK--HEVYPHGRVKRYPVLPRWRDD--VLLVGASIMDFQPWVISGEADPP 116
E+R ++L FFE+ H V P + DD +LLV A ++ F+P+ + GE PP
Sbjct: 5 EIRRRWLSFFEERGHTVVPSASLIA--------DDPTLLLVPAGMVPFKPYFL-GEVKPP 55
Query: 117 ANPLVISQPSIRFTDIDNVGITGRHFTIFEMMAHHAFN---------------------- 154
+ Q +R DI+ VG T RH T F+M + +F
Sbjct: 56 FDRATSVQKCVRTPDIEEVGKTTRHGTFFQMCGNFSFGDYFKEGAITYAWELLTSAQDKG 115
Query: 155 -YPGKP------IYWIDETVELAFEFFTKELKMKPEDITFKENPWAGG--GNAGPAFEVL 205
Y P +Y D+ E + + + + K+N W+ G G GP E+
Sbjct: 116 GYGLDPERLWITVYQDDDEAERIWHDVVGVPSERIQRLGKKDNYWSMGVPGPCGPCSEIN 175
Query: 206 Y-----------------RGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYVPMETKVVD 248
Y R +E+ LVFMQY++ E+ ++ + + +K +D
Sbjct: 176 YDRGPEFGVEGGPAVNDERYVEIWNLVFMQYERGEGIGKEEFEILGE------LPSKNID 229
Query: 249 TGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSRLAGMFDIEDMG 308
TG GLERL + QG Y+ ID + + N
Sbjct: 230 TGLGLERLAMILQGVQNMYE------------------IDTSMAVIN------------- 258
Query: 309 DLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSNVKAGYLAR 368
K E G++ + + + ++ DH + ++ DGV P N GY+ R
Sbjct: 259 -------KATELTGVAYGDAQASDVSLRVV---TDHMRTSVMLIGDGVTPGNEGRGYVLR 308
Query: 369 LLIRKSIRHLKELGLEVPL-SEIVALHIKELHKTFPEFKEMEDVILEIIDLEEKKYSETL 427
++R++IR+++ LG P+ +++ + I + + +PE + I ++ EE + +TL
Sbjct: 309 RIMRRAIRNMRLLGATGPVVKDLIDVVIGMMGQQYPELVTDRERIEKVALAEENAFLKTL 368
Query: 428 KRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKVHVPDNFYS 487
K G++++ ++ K G + + +K +++ G +L E+A ++G+ V D F
Sbjct: 369 KAGTNILDTAVSDTKASGGTVLAGDKAFLLHDTWGFPIDLTLEMAAEQGLSVD-EDGFRR 427
Query: 488 IVAKEAEKEKEEKEEEVVDF-------ELVKDLPETRTLYYEDPFMKEFEARVLRVIGDW 540
++ ++ E+ K + + + E+ T + Y D E E+ ++ ++ D
Sbjct: 428 LMKEQRERAKADAQAKKTGHAGAGAYREIADKAGATDFVGYTDT---ESESTIVGILVDG 484
Query: 541 -------------IVLDQTAFYPEGGGQPYDTGVLFVN-GSEVKVTNVQK-VGKVIVHK- 584
IVLD+T FY EGGGQ DTG + V+ G+ ++V + QK V V VHK
Sbjct: 485 ASSPAATEGDEVEIVLDRTPFYAEGGGQIGDTGRIRVDTGAVIEVRDCQKPVPGVYVHKG 544
Query: 585 VENPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTTDWAR 644
V G G + + ID RR R H+ TH+ AL LG QAGS+ R
Sbjct: 545 VVQVGEVTVGAKAQASIDDRRRKAIARAHSATHLTHQALRDALGPTAAQAGSENQPGRFR 604
Query: 645 LDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFRLYQGGVVPGRVI 704
D + + ++E+ N ++ D V + + EA+++ + G G +
Sbjct: 605 FDFGSPSAVPTAVMTDVEQKINEVLARDLDVRADVMGIDEAKKQGAIAEF--GEKYGERV 662
Query: 705 RVVKIEDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGEAAIKEWQKEREI 764
RVV I D+ + CGGTH+ +T +G +K+L I GV RI G A +E +
Sbjct: 663 RVVTIGDFSKELCGGTHVHNTAQLGLVKLLGESSIGSGVRRIEALVGVDAYSFLAREHTV 722
Query: 765 LKKASQVLRVPPEKLPETAERFFNEWKEARKEVEKLKKELAKLLVYELEAKVQKVKEYEF 824
+ + ++++ PE+LPE + K+A KE+EK + E L + V+
Sbjct: 723 VAQLQELIKGRPEELPEKVSAMLGKLKDAEKEIEKFRAEKVLQAAGGLADSAKDVRGVAL 782
Query: 825 I-GEIVEG-SMDDLREAV----ERLKKPNRIVV----LVSKEGYFAISVGDNV---NLNA 871
+ G++ +G + DDLR+ V R++ VV V+ + I+ + L A
Sbjct: 783 VTGQVPDGTTADDLRKLVLDVRGRIQGGRAAVVALFTTVNGKPLTVIATNEAARERGLKA 842
Query: 872 NDLAKKLTSIAGGGGGGRKDVAQGRIKDVSKAKEAIESIVKLL 914
DL + GGGGGG+ DVAQG ++ + +A++++ +L+
Sbjct: 843 GDLVRTAAKTLGGGGGGKPDVAQGGGQNAAAIGDAVDAVERLV 885
>sp|P56452|SYA_HELPY ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|7437616|pir||A64675 alanine--tRNA ligase (EC
6.1.1.7) - Helicobacter pylori (strain 26695)
>gi|2314404|gb|AAD08285.1| (AE000629) alanyl-tRNA
synthetase (alaS) [Helicobacter pylori 26695]
Length = 847
Score = 253 bits (640), Expect = 6e-66
Identities = 228/924 (24%), Positives = 406/924 (43%), Gaps = 168/924 (18%)
Query: 61 EMREKFLKFFEK--HEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPAN 118
++R +FL+FF+ H VYP P++P +L A ++ F+ + +G P+
Sbjct: 2 DIRNEFLQFFQNKGHAVYPS-----MPLVPN-DATLLFTNAGMVQFKD-IFTGIVPRPSI 54
Query: 119 PLVISQPSI-----RFTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFEF 173
P S + D++NVG T RH T+FEM+ + +F Y+ +E + A+EF
Sbjct: 55 PRAASSQLCMRAGGKHNDLENVGYTARHHTLFEMLGNFSFGD-----YFKEEAILFAWEF 109
Query: 174 FTKELKMKPEDITF---------------------------KENPWAGG--GNAGPAFEV 204
TK L KP+D+ K+N W G G GP E+
Sbjct: 110 VTKNLGFKPKDLYISVHEKDDEAVKLWEKFVPVDRIKKMGDKDNFWQMGDSGPCGPCSEI 169
Query: 205 LY-------------------RGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYVPMETK 245
R LE+ LVFMQY+++ + P+
Sbjct: 170 YIDQGEKHFKGSEDYFGGEGDRFLEIWNLVFMQYERSNDGVLS------------PLPKP 217
Query: 246 VVDTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSRLAGMFDIE 305
+DTG GLER+ + + +D+ L PL +E+I E ++ +
Sbjct: 218 SIDTGMGLERVQALLEHKLNNFDSSL---FAPL-----MEEISELTSLDYA--------- 260
Query: 306 DMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSNVKAGY 365
E + + R +ADH +A+ F+LA GV + GY
Sbjct: 261 --------------------SEFQPSFR------VVADHARAVAFLLAQGVHFNKEGRGY 294
Query: 366 LARLLIRKSIRHLKELGL-EVPLSEIVALHIKELHKTFPEFKEMEDVILEIIDLEEKKYS 424
+ R ++R+++RH +GL E L ++V + ++ T KE ++++++ EE+ +
Sbjct: 295 VLRRILRRALRHGYLMGLKEAFLYKVVGVVCEQFANTHAYLKESKEMVVKECFEEEEHFL 354
Query: 425 ETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKVHVPDN 484
ETL+ G +L + L + + + + Y++ G +L ++ G +
Sbjct: 355 ETLESGMELFNLSLKHLNENKIFDGKIA--FKLYDTFGFPLDLTNDMLRSHGACADM-QG 411
Query: 485 FYSIVAKEAEKEKE--EKEEEVVDFELVKDLPETRTL--------------YYEDPFMKE 528
F + ++ ++ K + ++ DF + + +++ F +
Sbjct: 412 FELCMQEQVKRSKASWKGKQNNADFSAILNAYAPNVFVGYETTECSAKVLGFFDSDFKEI 471
Query: 529 FEARVLRVIGDWIVLDQTAFYPEGGGQPYDTGVLFVNGSEVKVT-NVQKVGKVIVHKVEN 587
+A + + W++L++T FY EGGG D G LF + EV + + + + +E
Sbjct: 472 TDANPNQEV--WVLLEKTPFYAEGGGAIGDRGALFKDNGEVAIVLDTKNFFGLNFSLLEI 529
Query: 588 PGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTTDWARLDI 647
K+G +V ++ D R + +HH+ TH+L AL VLG HV QAGS + + R D
Sbjct: 530 KKALKKGDQVIAQVS-DERFEIAKHHSATHLLQSALREVLGSHVSQAGSLVESKRLRFDF 588
Query: 648 SHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFRLYQGGVVPGRVIRVV 707
SH K ++DEEL ++E L N + + E +P +A+ + L+ +RVV
Sbjct: 589 SHAKALNDEELEKVEDLVNAQIFKHLNSQVEHMPLNQAKDKGALALFSEKYAEN--VRVV 646
Query: 708 KIEDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGEAAIKEWQKEREILKK 767
++ ++ CGG H+ +TGL+G +I++ + GV RI CG+A + ++E + LK
Sbjct: 647 SFKEASIELCGGIHVENTGLIGGFRIVKESGVSSGVRRIEAVCGKAFYQLAKEENKELKN 706
Query: 768 ASQVLRVPPEKLPETAERFFNEWKEARKEVEKLKKELAKLLVYELEAKVQKVKEYEFIGE 827
A +L+ N+ KE+ K +K ++ V+K+ +
Sbjct: 707 AKTLLK------NNDVIAGINKLKESVKNSQKAP--------VSMDLPVEKIHGVNLVVG 752
Query: 828 IVEGSMDDLREAVERLK-KPNRIVVLVSKEGYFAISVG---DNVNLNANDLAKKLTSIAG 883
+VE D++E ++RLK K R++ +V K+ I++ N + AN A ++ I G
Sbjct: 753 VVE--QGDIKEMIDRLKSKHERLLAMVFKKENERITLACGVKNAPIKANVWANEVAQILG 810
Query: 884 GGGGGRKDVAQGRIKDVSKAKEAI 907
G GGGR D A KD+ + A+
Sbjct: 811 GKGGGRGDFASAGGKDIENLQAAL 834
>sp|O07438|SYA_MYCTU ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|7437633|pir||C70520 probable alaS protein -
Mycobacterium tuberculosis (strain H37RV)
>gi|3261815|emb|CAB09762.1| (Z97051) alaS [Mycobacterium
tuberculosis]
Length = 904
Score = 253 bits (640), Expect = 6e-66
Identities = 242/950 (25%), Positives = 402/950 (41%), Gaps = 161/950 (16%)
Query: 61 EMREKFLKFFEKHEVYPHGRVKRYPVLPRWRDD--VLLVGASIMDFQPWVISGEADPPAN 118
E+R++FL F K H V V+ DD +L V A ++ F P+ + G+ PP
Sbjct: 5 EIRKRFLDHFVKAG---HTEVPSASVI---LDDPNLLFVNAGMVQFVPFFL-GQRTPPYP 57
Query: 119 PLVISQPSIRFTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFEFFTKEL 178
Q IR DID VGIT RH T F+M + +F Y+ +ELA+ T L
Sbjct: 58 TATSIQKCIRTPDIDEVGITTRHNTFFQMAGNFSFGD-----YFKRGAIELAWALLTNSL 112
Query: 179 K-----MKPEDIT-----------------------------FKENPWAGG--GNAGPAF 202
+ PE I +N W+ G G GP+
Sbjct: 113 AAGGYGLDPERIWTTVYFDDDEAVRLWQEVAGLPAERIQRRGMADNYWSMGIPGPCGPSS 172
Query: 203 EVLY-----------------RGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYVPMETK 245
E+ Y R LEV LVFMQ ++ ED ++ P+ K
Sbjct: 173 EIYYDRGPEFGPAGGPIVSEDRYLEVWNLVFMQNERGEGTTKEDYQIL------GPLPRK 226
Query: 246 VVDTGYGLERLVWMSQGTPTAYDA-VLGYVVEPLKRMAGVEKIDERILMENSRLAGMFDI 304
+DTG G+ER+ + Q Y+ +L V++ + R+A A +D+
Sbjct: 227 NIDTGMGVERIALVLQDVHNVYETDLLRPVIDTVARVA----------------ARAYDV 270
Query: 305 EDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSNVKAG 364
+ D R IADH++ ++ DGV P N G
Sbjct: 271 GNHEDDVRYR-------------------------IIADHSRTAAILIGDGVSPGNDGRG 305
Query: 365 YLARLLIRKSIRHLKELGLEVPL-SEIVALHIKELHKTFPEFKEMEDVILEIIDLEEKKY 423
Y+ R L+R+ IR K LG++ + +++A + ++PE + I I EE +
Sbjct: 306 YVLRRLLRRVIRSAKLLGIDAAIVGDLMATVRNAMGPSYPELVADFERISRIAVAEETAF 365
Query: 424 SETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKVHVPD 483
+ TL GS L + KK G + + T ++++G EL E+A + G++V
Sbjct: 366 NRTLASGSRLFEEVASSTKKSGATVLSGSDAFTLHDTYGFPIELTLEMAAETGLQVD-EI 424
Query: 484 NFYSIVAKEAEKEKEE---KEEEVVDFELVKDLPETRTLYYEDPFMKEFEARVLRVIGDW 540
F ++A++ + K + ++ D ++L + + +AR+L + D
Sbjct: 425 GFRELMAEQRRRAKADAAARKHAHADLSAYRELVDAGATEFTGFDELRSQARILGIFVDG 484
Query: 541 ---------------------IVLDQTAFYPEGGGQPYDTGVLFVNGSE----VKVTNVQ 575
+VLD+T Y E GGQ D G + GS VT+VQ
Sbjct: 485 KRVPVVAHGVAGGAGEGQRVELVLDRTPLYAESGGQIADEGTISGTGSSEAARAAVTDVQ 544
Query: 576 KVGKVI-VHKVE-NPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQ 633
K+ K + VH+V G F EG V +D R + H+GTH++ AL +VLG + Q
Sbjct: 545 KIAKTLWVHRVNVESGEFVEGDTVIAAVDPGWRRGATQGHSGTHMVHAALRQVLGPNAVQ 604
Query: 634 AGSQLTTDWARLDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFRL 693
AGS + R D + ++D++ ++E + N V D +V +A+ L
Sbjct: 605 AGSLNRPGYLRFDFNWQGPLTDDQRTQVEEVTNEAVQADFEVRTFTEQLDKAKAMGAIAL 664
Query: 694 YQGGVVPGRVIRVVKIEDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGEA 753
+ G P V V + ++ CGGTH+ +T +GP+ IL I GV R+ G
Sbjct: 665 F-GESYPDEVRVVEMGGPFSLELCGGTHVSNTAQIGPVTILGESSIGSGVRRVEAYVGLD 723
Query: 754 AIKEWQKEREILKKASQVLRVPPEKLPETAERFFNEWKEARKEVEKLKKELAKLLVYELE 813
+ + KER ++ + L+VP E++P + A KE+E+++ A+
Sbjct: 724 SFRHLAKERALMAGLASSLKVPSEEVPARVANLVERLRAAEKELERVRMASARAAATNAA 783
Query: 814 AKVQKVKEYEFIGEIVEGSMD--DLREAVERLK-----KPNRIVVLVSKEGY---FAIS- 862
A Q++ + + + G M DLR + ++ +P + ++ E +A++
Sbjct: 784 AGAQRIGNVRLVAQRMSGGMTAADLRSLIGDIRGKLGSEPAVVALIAEGESQTVPYAVAA 843
Query: 863 --VGDNVNLNANDLAKKLTSIAGGGGGGRKDVAQGRIKDVSKAKEAIESI 910
++ + ANDL K+L G GGG+ D+AQG K+ + A++++
Sbjct: 844 NPAAQDLGIRANDLVKQLAVAVEGRGGGKADLAQGSGKNPTGIDAALDAV 893
>pir||C81396 alanine--tRNA ligase (EC 6.1.1.7) Cj0506 [imported] - Campylobacter
jejuni (strain NCTC 11168) >gi|6967975|emb|CAB75143.1|
(AL139075) alanyl-tRNA synthetase [Campylobacter jejuni]
Length = 842
Score = 242 bits (610), Expect = 2e-62
Identities = 237/938 (25%), Positives = 410/938 (43%), Gaps = 185/938 (19%)
Query: 61 EMREKFLKFFEK--HEVYPHGRVKRYPVLPRWRDD--VLLVGASIMDFQPWVISGEADPP 116
++R+ +L FF HE+ P P++P DD +L A ++ F+ + +GE P
Sbjct: 2 DIRKAYLDFFASKGHEITPSS-----PLVP---DDATLLFTNAGMVPFKS-IFTGEIPRP 52
Query: 117 ANPLVIS-QPSIR----FTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAF 171
P S Q IR D+DNVG T RH T FEM+ + +F Y+ ++ + A+
Sbjct: 53 NPPRKTSCQTCIRAGGKHNDLDNVGYTARHHTFFEMLGNFSFGD-----YFKEQAIAYAW 107
Query: 172 EFFTKELKMKPEDITF----------------------------KENPWAGG--GNAGPA 201
EF T+ LK+ P+D + K+N W G G GP
Sbjct: 108 EFVTEVLKL-PKDRLYVTVHENDDEAFNLWQKHIQKERIYKFGDKDNFWQMGDTGPCGPC 166
Query: 202 FEVLY-------------------RGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYVPM 242
E+ Y R LE+ LVFMQY+++ + P+
Sbjct: 167 SEIFYDQGQEHFNSSEDYMGGDGDRFLEIWNLVFMQYERSADGVLS------------PL 214
Query: 243 ETKVVDTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSRLAGMF 302
+DTG GLER+ + +G + +D+ L + + +I
Sbjct: 215 PKPSIDTGMGLERVTAIKEGKFSNFDSSLFMPI--------INEIS-------------- 252
Query: 303 DIEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSNVK 362
KL K + G S IADH ++ F+LA GV
Sbjct: 253 --------KLCNKTYVYESGASFR-------------VIADHIRSSVFLLAQGVSFDKEG 291
Query: 363 AGYLARLLIRKSIRHLKELGLEVP-LSEIVALHIKELHKTFPEFKEMEDVILEIIDLEEK 421
GY+ R ++R+++RH LG + + ++V + + + E +D I E I LEE+
Sbjct: 292 RGYVLRRILRRALRHGYLLGFKQAFMYKLVDVVCDLMGGHYTYLNEKKDFIKEQIRLEEE 351
Query: 422 KYSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKVHV 481
++ T++ G ++ E+ K+ E+ + Y+++G +L ++ ++ +KV
Sbjct: 352 RFLSTIENGIEIFNEELKNTKEIFSGEVAFK----LYDTYGFPLDLTADMLREKNLKVDE 407
Query: 482 PD-----NFYSIVAKEAEKEKEEKEEEVVDFELVKDLPETRTLYYEDPFMKEFEARVLRV 536
N AK + K +K L++ E + YE E E+++L +
Sbjct: 408 EKFELFMNEQKARAKASWKGSGDKTASGDFKNLLEKFGENHFVGYEKA---ECESKILAL 464
Query: 537 IGD------------WIVLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTNVQKVGKVIVHK 584
+ + W++L+ T FY GGQ D+G + ++ +V + QK + +
Sbjct: 465 LDEDFKEVSTLKDAGWVMLENTPFYATSGGQSADSGFI----AKREVLDTQKFFNLNLSF 520
Query: 585 VENPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTTDWAR 644
++ K V RID ++R Q RHH+ TH+L AL +LG HV QAGS + ++ R
Sbjct: 521 IKAGEELKVNDIVHARIDTEKREQIARHHSATHLLHHALREILGSHVSQAGSLVESNKLR 580
Query: 645 LDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFRL----YQGGVVP 700
D +H+K ++ EEL IE+ N++++ + E +P EA++ L YQG V
Sbjct: 581 FDFTHHKALNKEELESIEKRVNKMIINSSEAILENMPLEEAKKSGAIALFNEKYQGNV-- 638
Query: 701 GRVIRVVKIEDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGEAAIKEWQK 760
RV+ + + + CGGTH+ +T +G I++ + GV RI +AA++ +
Sbjct: 639 ----RVLTLGE-SKELCGGTHVKNTAQIGSFYIVKESGVSAGVRRIEAVVSKAALEFVKN 693
Query: 761 EREILKKASQVLRVPPEKLPETAERFFNEWKEARKEVEKLKKELAKLLVYELEAKVQKVK 820
+ E L K L+ + K+ + E+ LK EL EL++K ++
Sbjct: 694 QLEELSKVKDELK---------NNDILSGIKKLKNEILSLKNELKNSSKTELDSK--NIQ 742
Query: 821 EYEFIGEIVEGSMDDLREAVERLKK--PNRIVVLVS-KEGYFAISVG-DNVNLNANDLAK 876
E + ++ D++ ++ K +++L+ K+ ++ G +V L A L K
Sbjct: 743 GVEICVKRIDNG--DIKAMIDDFKNKFAKAVILLIQVKDEKITLAAGVKDVPLKAGALVK 800
Query: 877 KLTSIAGGGGGGRKDVAQGRIKDVSKAKEAIESIVKLL 914
+ I GG GGGR D A KD+SK EA++ ++ +
Sbjct: 801 EAAQILGGNGGGRDDFATAGGKDLSKINEALKQSLETI 838
>sp|P57483|SYA_BUCAI ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|10039072|dbj|BAB13106.1| (AP001119) alanyl-tRNA
synthetase [Buchnera sp. APS]
Length = 878
Score = 237 bits (598), Expect = 5e-61
Identities = 224/930 (24%), Positives = 404/930 (43%), Gaps = 169/930 (18%)
Query: 56 KYTLDEMREKFLKFFEK--HEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEA 113
K T D++R+ FLKFF++ H + P + Y D LL + M+ + GE
Sbjct: 2 KKTTDKIRQDFLKFFKEKGHMIIPSSSLVPY------NDSTLLFTNAGMNQFKEIFLGEK 55
Query: 114 DPPANPLVISQPSIR----FTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVEL 169
+ Q +R D++NVG T +H T FEM+ + +F Y+ + +E
Sbjct: 56 KSNYPRVATVQRCLRTGGKHNDLENVGYTSKHHTFFEMLGNFSFGD-----YFKKQAIEY 110
Query: 170 AFEFFTKELKM------------KPEDITFK--------------------------ENP 191
A+E T + K + T+K EN
Sbjct: 111 AWELLTSKKWFNIPQNKLWISVYKDDTETYKIWNDIIKIPSERIIRIGDKNKEKYNSENF 170
Query: 192 WAGG--GNAGPAFEVLY-------------------RGLEVATLVFMQYKKAPENAPEDQ 230
W G G GP E+ Y R +E+ +VF+++ +
Sbjct: 171 WQMGDTGPCGPCTEIFYDYSDTMKIDPIEFLENKNGRFVEIWNIVFIEFNR--------- 221
Query: 231 VVIIKGDRYVPMETKVVDTGYGLERLVWMSQGTPTAYDA-VLGYVVEPLKRMAGVEKIDE 289
I + + ++ K +DTG GLER+ + Q + Y V +++ + +++ + +D
Sbjct: 222 ---ISKTKIISLKNKSIDTGMGLERISAVLQNVYSNYHIDVFQKLIKNIAQLSSINNLDH 278
Query: 290 RILMENSRLAGMFDIEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALT 349
IS + IADH ++ +
Sbjct: 279 ---------------------------------ISFQ-------------VIADHIRSCS 292
Query: 350 FMLADGVIPSNVKAGYLARLLIRKSIRHLKELGLEVPL-SEIVALHIKELHKTFPEFKEM 408
+++AD ++PSN GY+ R +IR+++RH ++G++ ++V+ I + KT KE
Sbjct: 293 YIIADNILPSNEHRGYILRRIIRRALRHGHKIGIKKNFFHKLVSSVIHVMGKTGDILKEK 352
Query: 409 EDVILEIIDLEEKKYSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELV 468
++ I ++ +EE ++S TL++G ++ EI K+ +S + Y++ G +L
Sbjct: 353 QEKIENVLKIEEMQFSYTLEKGLKILNSEIEKIDNNILSG---KTAFYLYDTFGFPIDLT 409
Query: 469 KEIAEKEGIKVHVPDNFYSIVAKEAEKEKEEKEEEVVD-------------FE-LVKDLP 514
++ ++ IK+ N Y + AKE +KE+ ++ FE K +
Sbjct: 410 SDVCREKNIKIDY--NSYEL-AKEKQKEQSNINKKFYKNYNNNIILNDTCIFEGYTKTI- 465
Query: 515 ETRTLYYEDPFMKEFEARVLRVIGDWIVLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTNV 574
TR+L + +++++ I LD+T FY E GGQ D G L+ S V
Sbjct: 466 -TRSLVKYIFVNNQSVSKIIKDEKGVIFLDKTPFYSESGGQIGDIGQLYHKKSSFLVEKT 524
Query: 575 QKVGKVIVHKVEN-PGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQ 633
+K GK I H + G + ID D R +H+ TH+L L ++LG + Q
Sbjct: 525 KKYGKTIGHIGKLISGQITLNDSLFSHIDEDYRYAIQLNHSATHLLHATLRKILGDSIVQ 584
Query: 634 AGSQLTTDWARLDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFRL 693
GS +T + R D S+ K I ++++IE + N + + K+ E L EA+++ L
Sbjct: 585 KGSLVTNTYLRFDFSYVKSIDTSQIQKIENIINTNIRNNIKIKTEELNLEEAKKKKAMAL 644
Query: 694 YQGGVVPGRVIRVVKIEDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGEA 753
+ G ++RVV I ++ ++ CGGTH TG +G KI+ + G++RI G+
Sbjct: 645 FDDQY--GSIVRVVFINNFSIELCGGTHTQRTGDIGLFKIISQSSVASGIKRIEAVTGQK 702
Query: 754 AIKEWQKEREILKKASQVLRVPPEKLPETAERFFNEWKEARKEVEKLKKELAKLLVYELE 813
AI ++ +K S +L + E ++ + K K++ +L+K+ + ++
Sbjct: 703 AIDYLHEKDNYIKDISLLLNCSTVDIKEKTKKLTIKTKNLEKKIIQLQKKENTQYIKKIL 762
Query: 814 AKVQKVKEYEFIGEI-VEGSMDDLREAVERLKK--PNRIVVLVS-KEGYFAISVGDNVNL 869
V ++K + + I + LR V++LKK N I++L++ F I VG NL
Sbjct: 763 KNVTEIKGTKLLTNIFYDYEQKSLRMIVDQLKKELKNTIIILINIINNRFTIIVGVTRNL 822
Query: 870 ----NANDLAKKLTSIAGGGGGGRKDVAQG 895
A + + + + G GGG+K++A+G
Sbjct: 823 LDYITAIKIMEMIINKTNGKGGGKKEIAEG 852
>pir||G82310 alanyl-tRNA synthetase VC0545 [imported] - Vibrio cholerae (group
O1 strain N16961) >gi|9654973|gb|AAF93713.1| (AE004140)
alanyl-tRNA synthetase [Vibrio cholerae]
Length = 860
Score = 235 bits (594), Expect = 1e-60
Identities = 234/947 (24%), Positives = 395/947 (41%), Gaps = 196/947 (20%)
Query: 60 DEMREKFLKFFEKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPANP 119
DE+R FL FFE H V+ ++P +L A + F+ + E
Sbjct: 6 DEVRRAFLSFFESKG---HQIVESSSLVPANDPTLLFTNAGMNQFKDCFLGLEKRAYTRA 62
Query: 120 LVISQPSIR----FTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFEFFT 175
+Q +R D++NVG T RH T FEM+ + +F Y+ ++ ++ A+EF T
Sbjct: 63 TT-AQRCVRAGGKHNDLENVGFTARHHTFFEMLGNFSFGD-----YFKEDAIQYAWEFLT 116
Query: 176 KELKMKPE--------------DITFK-----------------------ENPWAGG--G 196
L++ E DI K +N W G G
Sbjct: 117 DVLQLPKERLLVTVYETDDEAFDIWNKKVGIPADRIIRIGDKKGGKKFDSDNFWQMGDTG 176
Query: 197 NAGPAFEVLY-------------------RGLEVATLVFMQYKKAPENAPEDQVVIIKGD 237
GP E+ Y R +E+ VFMQ+ + + E
Sbjct: 177 PCGPCTEIFYDHGDHIWGGPPGSPEEDGDRFIEIWNNVFMQFNRHADGTME--------- 227
Query: 238 RYVPMETKVVDTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSR 297
P+ VDTG G+ER+ + QG + Y+
Sbjct: 228 ---PLPKPSVDTGMGIERISAIMQGVHSNYE----------------------------- 255
Query: 298 LAGMFDIEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVI 357
D+ + L K A+ +G + +++R +ADH ++ F++ DGV+
Sbjct: 256 ----IDV-----FQTLIKAAADAIGYQ-DLTNQSLR------VVADHIRSCAFLIVDGVM 299
Query: 358 PSNVKAGYLARLLIRKSIRHLKELGLEVPLSEIVALHIKELHKTFP-EFKEMEDVILEII 416
PSN GY+ R +IR+++RH +LG + + + E+ T E K+ + ++ +++
Sbjct: 300 PSNEGRGYVLRRIIRRAVRHGNKLGAQGAFFHKLVGPLAEVMGTAGVELKKQQALVEKVL 359
Query: 417 DLEEKKYSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEG 476
+EE+ + TL RG ++ + +L + + E + Y+++G +L ++A + G
Sbjct: 360 RIEEENFGRTLDRGMSILNDALDQLSGQVLDG---ETVFKLYDTYGFPADLTNDVARERG 416
Query: 477 IKVHVPDNFYSIVAKEAEKEKEEKEEEVVDFELVKDLPETRTLYY---------EDPFMK 527
+ F + ++ ++ +E + L+K T Y + F++
Sbjct: 417 FSIDEA-GFEQAMEEQRQRAREAGQFGTDYNSLIKSATNTEFCGYTASRGQSVVREMFVE 475
Query: 528 EFEARVLRVIGDW--IVLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTNVQKVGKVIVHK- 584
E L GD IVLD T FY E GGQ DTGVL + V + QK+G I H
Sbjct: 476 GAEVSTLSA-GDKAIIVLDNTPFYAESGGQCGDTGVLKTDAGIFHVEDTQKLGNAIAHHG 534
Query: 585 VENPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTTDWAR 644
V G+ G +V +D RR +H+ TH+L AL +VLG+HV Q GS + + R
Sbjct: 535 VIAQGVLATGDQVDAIVDEKRRAAISLNHSATHLLHAALRKVLGEHVAQKGSLVRAETLR 594
Query: 645 LDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFRLYQGGVVPGRVI 704
D SH + ++ E++E+ERL N+ V + + + EA+ + L+ G +
Sbjct: 595 FDFSHLEAMTAAEIKEVERLVNQEVRRNHSIETNIMNIDEAKAKGAMALF--GEKYDDQV 652
Query: 705 RVVKIEDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGEAAI-----KEWQ 759
RV+ + D+ + CGG H +TG +G KI+ I G+ RI GE A+ ++ Q
Sbjct: 653 RVLSMGDFSTELCGGIHASNTGDIGLFKIISEGGIAAGIRRIEAVTGEGALDYLDAQQAQ 712
Query: 760 KEREILKKASQVLRVPPEKLPETAERFFNEWKEARKEVEKLKKELAKLLVYELEAKVQKV 819
+ ++ + A++ K KE+++LK +LA E + +V
Sbjct: 713 HDAKVSEMAAKA-------------------KLLEKEIQQLKDKLA---AKESAGLINQV 750
Query: 820 KEYEFIGEIV-----------EGSMDDLREAVERLKKPNRIVVL----VSKEGYFAISVG 864
K+ + +V G +DDL+ + + I++L K G A
Sbjct: 751 KQIAGVNVLVAQLNGADNKALRGMVDDLKNQLS-----SGIIMLGNVAEGKVGLIAGVTN 805
Query: 865 DNVN-LNANDLAKKLTSIAGGGGGGRKDVAQGRIKDVSKAKEAIESI 910
D N + A +L + GG GGGR D+AQ D A+ES+
Sbjct: 806 DLTNKVKAGELVNMVALQVGGKGGGRPDMAQAGGTDAHALPSALESV 852
>sp|P43815|SYA_HAEIN ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|1073831|pir||I64095 alanine--tRNA ligase (EC
6.1.1.7) - Haemophilus influenzae (strain Rd KW20)
>gi|1573826|gb|AAC22473.1| (U32763) alanyl-tRNA
synthetase (alaS) [Haemophilus influenzae Rd]
Length = 874
Score = 234 bits (591), Expect = 3e-60
Identities = 229/936 (24%), Positives = 391/936 (41%), Gaps = 159/936 (16%)
Query: 58 TLDEMREKFLKFFEKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPA 117
T E+R+ FL FF H V+ ++P +L A + F+ + + P +
Sbjct: 3 TTAEIRQSFLDFFHSKG---HQVVESSSLVPENDPTLLFTNAGMNQFKDVFLGMDKRPYS 59
Query: 118 NPLVISQ---PSIRFTDIDNVGITGRHFTIFEMMAHHAFN-------------YPGKPIY 161
+ P + D++NVG T RH T FEM+ + +F Y P +
Sbjct: 60 RATTAQRCVRPGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKQDAINFAWEYLTSPQW 119
Query: 162 --------WID--ETVELAFEFFTKELKMKPEDIT----------FKENPWAGG--GNAG 199
W+ ET + A+ + K++ + E I +N WA G G G
Sbjct: 120 LGLPKEKLWVTVYETDDEAYNIWNKDVGVPAERIIRIGDNKGSPYASDNFWAMGDTGPCG 179
Query: 200 PAFEVLY-------------------RGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYV 240
P E+ Y R +E+ +VFMQ+ + + E
Sbjct: 180 PCTEIFYDHGDHIWGGPPGSPEEDGDRYIEIWNVVFMQFNRLADGTMEK----------- 228
Query: 241 PMETKVVDTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSRLAG 300
+ VDTG GLER+ + Q + Y+
Sbjct: 229 -LPRPSVDTGMGLERISAVLQHVNSNYE-------------------------------- 255
Query: 301 MFDIEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSN 360
DI K L K AE VG + + K++R IADH ++ +++ADGVIPSN
Sbjct: 256 -IDI-----FKTLIAKTAEIVG-ATDLTNKSLR------VIADHIRSCAYLIADGVIPSN 302
Query: 361 VKAGYLARLLIRKSIRHLKELGL-EVPLSEIVALHIKELHKTFPEFKEMEDVILEIIDLE 419
GY+ R +IR+++RH LG E ++V I + + + K + + +++ LE
Sbjct: 303 EGRGYVLRRIIRRAVRHGHLLGAKESFFYKLVPTLIDVMAEAGKDVKAKQTNVEKLLRLE 362
Query: 420 EKKYSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKV 479
E++++ TL+RG L+ ++++K +S E Y+++G +L ++ + I +
Sbjct: 363 EEQFARTLERGLSLLDEALSQVKDGILSG---EVAFKLYDTYGFPLDLTADVCRERNITI 419
Query: 480 HVPDNFYSIVAKEAEKE-------------KEEKEEEVVDFELVKDLPETRTLYYEDPFM 526
+ A+ + + + E + + V+ + L+Y+ +
Sbjct: 420 DEQAFDRKMEAQRTRAQAASQFGVDYNSVIRVDGETKFEGYTEVESQAKITALFYDGKSV 479
Query: 527 KEFEARVLRVIGDWIVLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTNVQKVGKVIVHKVE 586
+ EA V+ +L+ T FY E GGQ D+G L V + QK G+V H E
Sbjct: 480 ESIEAGQSAVV----ILENTPFYAESGGQIGDSGYLSTQSVTFNVKDTQKYGQVFGHIGE 535
Query: 587 -NPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTTDWARL 645
G K G V +D RR +H+ TH+L AL ++LG HV Q GS ++ R
Sbjct: 536 LTQGSLKVGQSVNAIVDAKRRHNTSLNHSATHLLHAALRQILGLHVVQKGSLVSDKALRF 595
Query: 646 DISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFRLYQGGVVPGRVIR 705
D + + I+ E+L EIE L N+ + + V + + A+ + L+ G G +R
Sbjct: 596 DFAQPEAITKEQLSEIETLVNQKIRANFPVQTDIMDIDSAKAKGAMALF--GEKYGDKVR 653
Query: 706 VVKIEDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGEAAIKEWQKEREIL 765
V+ + D+ ++ CGG H TG +G KI+ + G+ RI G+ AI ++ IL
Sbjct: 654 VLTMGDFSIELCGGIHAKRTGDIGLFKIITENAVAAGIRRIEAVTGQNAIDWLHNQQRIL 713
Query: 766 KKASQVLRVPPEKLPETAERFFNEWKEARKEVEKLKKELAKLLVYELEAKVQKVKEYEFI 825
+++ +L+ L E ++ ++ K+ KE++ LK++ A K+ I
Sbjct: 714 TQSADLLKSDVNTLAEKIQQLQDKAKKVEKELQGLKEKAAMQAGSYFVKSAVKINGVSVI 773
Query: 826 GEIVEG-SMDDLREAVERLKKPNRIVVLVSKEGYFAISVGDNVNL------------NAN 872
+ ++G LR V+ LK V+ FA + + VNL A
Sbjct: 774 AQQLDGIETKSLRVMVDDLKNQLGSGVIA-----FASILDEKVNLVVGVTNDLTAKIKAG 828
Query: 873 DLAKKLTSIAGGGGGGRKDVAQGRIKDVSKAKEAIE 908
+L + GG GGGR D+A + +AI+
Sbjct: 829 ELVNLMAQQVGGKGGGRPDMAMAGGSQLENVTQAIK 864
>pir||C82844 alanyl-tRNA synthetase XF0124 [imported] - Xylella fastidiosa
(strain 9a5c) >gi|9104908|gb|AAF82937.1|AE003866_2
(AE003866) alanyl-tRNA synthetase [Xylella fastidiosa]
Length = 916
Score = 231 bits (584), Expect = 2e-59
Identities = 238/964 (24%), Positives = 401/964 (40%), Gaps = 187/964 (19%)
Query: 48 IGKPGIPKKYTLDEMREKFLKFFEK--HEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQ 105
+ IP K+T ++R FL+FF+ H++ P P++P +L + ++ F+
Sbjct: 30 VNSMNIPTKFTTSKIRSDFLEFFKNKGHKIVPSA-----PLVPGNDPTLLFTNSGMVQFK 84
Query: 106 PWVISGEADPPANPLVIS---QPSIRFTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYW 162
+ E + + + D+D+VG T RH T FEM+ + +F Y+
Sbjct: 85 DVFLGAEKRSEVRVADVQCCLRAGGKHNDLDSVGYTARHHTFFEMLGNWSFGD-----YF 139
Query: 163 IDETVELAFEFFTKELKMKPEDITF----------------------------------- 187
E + A+E T ++ PE +
Sbjct: 140 KKEAITWAWELLTHVWELPPERLLVTVYHTDDESYALWRDMVGVPEDRIVRIGDNKGAPF 199
Query: 188 -KENPW--AGGGNAGPAFEVLY-------------------RGLEVATLVFMQYKKAPEN 225
+N W A G GP E+ Y R +E+ LVFMQ+ + +
Sbjct: 200 ASDNFWQMADTGPCGPCTEIFYDHGEHIPGGPPGSPDEDGDRFIEIWNLVFMQFDRQSDG 259
Query: 226 APEDQVVIIKGDRYVPMETKVVDTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVE 285
VP+ VDTG GLERL + Q T Y+ L
Sbjct: 260 T------------LVPLPAPCVDTGMGLERLAAILQHVHTNYEIDLF------------- 294
Query: 286 KIDERILMENSRLAGMFDIEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHT 345
+ ++++ + L + D+++ K++R IADH+
Sbjct: 295 ---QTLILKAAELTAVADVQN-----------------------KSLR------VIADHS 322
Query: 346 KALTFMLADGVIPSNVKAGYLARLLIRKSIRHLKELGLEVP-LSEIVALHIKELHKTFPE 404
+A F++ DGV+PSN GY+ R +IR+++RH LG+ P + +V + + +P+
Sbjct: 323 RACAFLIVDGVLPSNEGRGYVLRRIIRRALRHGWMLGVRQPFFNNMVPTLVAVMGDAYPK 382
Query: 405 FKEMEDVILEIIDLEEKKYSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLT 464
+ + ++ + EE++++ETL G + AK+ IP Y+++G
Sbjct: 383 LQAAAESVMRTLLAEEERFAETLDVGMKIFNEVAAKVAN---GVIPGSDAFRLYDTYGFP 439
Query: 465 PELVKEIAEKEGIKVHVPDNFYSIVAKEAEKEKEEKEEEV---------VDFELVKDLPE 515
+L +IA + G+ V +V EA ++ K + E L
Sbjct: 440 VDLTADIARERGMSV-------DMVGFEAAMTQQRKTARAAGKFGRGVQLSAERAAMLSP 492
Query: 516 TRTLYYEDPFMKEFEARVLRV--------------IGDWIVL--DQTAFYPEGGGQPYDT 559
T L YE + +A LRV +GD +++ D+T FY E GGQ D
Sbjct: 493 TVFLGYE-----QLQADGLRVVALLSDGGLTDSASVGDEVIVLTDRTPFYAESGGQVGDI 547
Query: 560 GVLFV-NGSEVKVTNVQK-VGKVIVHKVE-NPGLFKEGMEVRGRIDWDRRIQHMRHHTGT 616
G L +G ++VT+ QK +G+ H G K G + G + RR +H+ T
Sbjct: 548 GTLMASDGVRLEVTDTQKLMGQFHGHVARIVQGGVKVGDVLSGSVAVARRKMVALNHSAT 607
Query: 617 HVLMGALVRVLGKHVWQAGSQLTTDWARLDISHYKRISDEELREIERLANRIVMEDRKVT 676
H+L AL V G HV Q GS + D R D SH++ I+ ++ IER+ N V + V
Sbjct: 608 HLLHCALRSVFGTHVVQKGSLVAPDRLRFDFSHFEPIAAAQMTLIERMVNDEVRANHLVM 667
Query: 677 WEWLPRTEAEQRYGFRLYQGGVVPGRVIRVVKIEDWDVQACGGTHLPSTGLVGPIKILRT 736
E + A L+ G G +RVV + V+ CGGTH+ TG +G KI+
Sbjct: 668 IEQMGMQAALDAGAMALF--GEKYGEHVRVVTM-GTSVELCGGTHINRTGDIGLFKIISE 724
Query: 737 ERIQDGVERIIFACGEAAIKEWQKEREILKKASQVLRVPPEKLPETAERFFNEWKEARKE 796
+ GV RI GE+A+ E L + + ++ + + + K +E
Sbjct: 725 CGVSSGVRRIEAVTGESALNHVLAEEHRLYEVAGLIGSNANDVVNHIRQLTDRQKTLERE 784
Query: 797 VEKLKKELAKLLVYELEAKVQKVKEYEFIGEIVEG-SMDDLREAVERLK--KPNRIVVLV 853
+EKLK +L + +L + V + + + ++G LREA++RLK + ++VL
Sbjct: 785 LEKLKGKLISGTITDLLSTAVNVADVKVVAARLDGLDGKALREALDRLKLQLSDAVIVLA 844
Query: 854 SKEGYFAISVGDNVN-------LNANDLAKKLTSIAGGGGGGRKDVAQGRIKDVSKAKEA 906
G +++ VN + A+ L + + G GGGR D AQG +D + A
Sbjct: 845 GVTG-GKVALVTAVNGRRAMGKVKADTLLSHVATQINGRGGGRVDFAQGGGEDGPSLRSA 903
Query: 907 IESI 910
++ +
Sbjct: 904 LDGV 907
>pir||H81739 alanyl-tRNA synthetase TC0125 [imported] - Chlamydia muridarum
(strain Nigg) >gi|7190160|gb|AAF39003.1| (AE002279)
alanyl-tRNA synthetase [Chlamydia muridarum]
Length = 875
Score = 231 bits (584), Expect = 2e-59
Identities = 237/940 (25%), Positives = 404/940 (42%), Gaps = 167/940 (17%)
Query: 62 MREKFLKFFEKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPANPLV 121
+R FLKF+ H V PV P +L A + F+ + G+
Sbjct: 6 LRSNFLKFYTNRN---HTPVASSPVFPYNDPSILFTNAGMNQFKN-IFLGKEQTSYTRAT 61
Query: 122 ISQPSIR----FTDIDNVGITGRHFTIFEMMAHHAF--------------------NYPG 157
SQ IR D++NVG T RH T FEM+ + +F N+
Sbjct: 62 TSQKCIRAGGKHNDLENVGHTSRHLTFFEMLGNFSFGDYFKQDAISFAWEVSLSVFNFDP 121
Query: 158 KPIY-WIDETVELAFEFFTKELKM-KPEDITFKENPW--AGGGNAGPAFEVLY------- 206
IY + E + AF + K L + +T K+N W A G G E+L+
Sbjct: 122 DFIYATVHEKDDEAFALWEKYLPTNRIFRLTDKDNFWSMADTGPCGFCSELLFDRGEKFG 181
Query: 207 ------------RGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYVPMETKVVDTGYGLE 254
R LE LVFM++ + + + ++ K VDTG GLE
Sbjct: 182 KATSPLEDADGERFLEYWNLVFMEFNRTSDGT------------LLALQKKCVDTGAGLE 229
Query: 255 RLVWMSQGTPTAYDA-VLGYVVEPLKRMAGVEKIDERILMENSRLAGMFDIEDMGDLKLL 313
RLV + T T ++A VL +++ A VE + E F +
Sbjct: 230 RLVSLLSETDTVFEADVLRHLI------AKVENLSEITYSPTESKGSAFRV--------- 274
Query: 314 RKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSNVKAGYLARLLIRK 373
IADH ++L+F + DG++P N + GY+ R ++R+
Sbjct: 275 ---------------------------IADHVRSLSFAITDGLLPGNTERGYVLRKILRR 307
Query: 374 SIRHLKELGLEVP-LSEIVALHIKELHKTFPEFKEMEDVILEIIDLEEKKYSETLKRGSD 432
++ + K LG P L+EIV I+ + + +PE + E I E++ EE+ + +TL+RG +
Sbjct: 308 AVNYGKRLGFHRPFLAEIVPSLIETMGEAYPELQAAETQIQEVLTTEEEHFFKTLQRGGN 367
Query: 433 LVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKVHVPDNFYSIVAKE 492
L+ + + +S+I E +++GL + + +A+ V + D F + +
Sbjct: 368 LLHQVLKS--SASLSKISGEDAFKLKDTYGLPIDEIALLAKDHNYTVDM-DTFRKLEMEA 424
Query: 493 AEKEKEEKEEEVVDFELV-KDLPETRTLYYE-------DPFMK------EFEARVLRVIG 538
E+ ++ + D + + +D+ T T + D F++ E + +
Sbjct: 425 KERSRKNTVKNKNDSDSIFQDVDPTNTSEFVGYDMLSCDTFIEGIVKYNEIASTLEEGEE 484
Query: 539 DWIVLDQTAFYPEGGGQPYDTGVLFVNGSEVKV--TNVQKVGKVIVHKVENPGLFKEGME 596
I+L T FY E GGQ D+G +F V T K G + H + G + M
Sbjct: 485 GAIILRTTPFYAEKGGQVGDSGEIFCESGTFLVSHTTTPKAGLIAHHGKLSQGSLQTTMA 544
Query: 597 VRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTTDWARLDISHYKRISDE 656
V +++ + R + +HTG H+L AL LG+H+ QAGS + + RLD SH K +S E
Sbjct: 545 VTAQVNQNLRKKIANNHTGCHLLHKALEVSLGEHIRQAGSYVDSQKIRLDFSHNKALSPE 604
Query: 657 ELREIERLANRIVMEDRKVT------WEWLPRTEAEQRYGFRLYQGGVVPGRVIRVVKIE 710
EL IE L N + E+ VT + + +E +Q +G + G ++RVV
Sbjct: 605 ELLTIETLVNEKIRENVPVTIREALYSDVMNSSEIKQFFGDKY-------GDIVRVVS-A 656
Query: 711 DWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGEAAIKEWQKEREILKKASQ 770
+ + CGGTH +TG +G +I + + G+ RI GE A + + L + +
Sbjct: 657 GFSHELCGGTHARATGDIGYFRITKEHAVSTGIRRIEATTGEDAENIARGQDTDLNEIAT 716
Query: 771 VLRVPPEKLPETAERFFNEWKEARKEVEKLKKELAKLLVYELEAKVQKVKEYEFI----- 825
+++ P ++L E K+ K++ L+ +L + V L KV E ++
Sbjct: 717 IIQSPKDQLLVKLRNVMEEKKDLAKQLANLENQLVQQQVKSLLTSCDKVNETSYLVYHLT 776
Query: 826 ---GEIVEGSMDDLREAVER-------LKKPNRIVVLVSKEGYFAISVGDNV---NLNAN 872
G+ ++ + L + V +K +R +VLV V D++ ++A
Sbjct: 777 EEEGQRIQHYANTLHKEVPAKFISLWVTEKNDRYIVLV--------RVSDDLVKQGIDAQ 828
Query: 873 DLAKKLTSIAGGGGGGRKDVAQGRIKDVSKAKEAIESIVK 912
L ++L + GG GG+ AQG K++ + E + +I++
Sbjct: 829 ALLEELLAPYGGRCGGKAVSAQGSSKELPQI-EVLNTILR 867
>gb|AAC49007.1| (U18672) cytoplasmic alanyl-tRNA synthetase [Saccharomyces
cerevisiae] >gi|1097386|prf||2113423A Ala-tRNA
synthetase [Saccharomyces cerevisiae]
Length = 958
Score = 230 bits (580), Expect = 6e-59
Identities = 256/1005 (25%), Positives = 424/1005 (41%), Gaps = 200/1005 (19%)
Query: 52 GIPKKYTLDEMREKFLKFFEKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISG 111
G +K+T +R FL +F+ E H VK PV+P +L A + ++P + G
Sbjct: 4 GDKQKWTATNVRNTFLDYFKSKE---HKFVKSSPVVPFDDPTLLFANAGMNQYKP-IFLG 59
Query: 112 EADPPANPLVI-----SQPSIR----FTDIDNVGITGRHFTIFEMMAHHAFNYPGKP--- 159
DP ++ + SQ IR D+++VG H T FEM+ + +F K
Sbjct: 60 TVDPASDFYTLKRAYNSQKCIRAGGKHNDLEDVGKDSYHHTFFEMLGNWSFGDYFKKEAI 119
Query: 160 ---------IYWI------------DETVELAFEFFTKELKMK---PEDITF----KENP 191
+Y I DE + L + +EL P+D K+N
Sbjct: 120 TYSWTLLTEVYGIPKDSLYVTYFEGDEKLGLEPDTEARELWKNVGVPDDHILPGNAKDNF 179
Query: 192 WAGG--GNAGPAFEVLYRG-----------------LEVATLVFMQYKKAPENAPEDQVV 232
W G G GP E+ Y LEV LVF+Q+ + + + +
Sbjct: 180 WEMGDQGPCGPCSEIHYDRIGGRNAASLVNMDDPDVLEVWNLVFIQFNREQDGSLK---- 235
Query: 233 IIKGDRYVPMETKVVDTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERIL 292
P+ K +DTG G ERLV + Q + YD V PL E+I E +
Sbjct: 236 --------PLPAKHIDTGMGFERLVSVLQDVRSNYDTD---VFTPL-----FERIQE--I 277
Query: 293 MENSRLAGMFDIEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFML 352
+G F D + ++ A R +ADH + LTF L
Sbjct: 278 TSVRPYSGNFGENDK------------------DGIDTAYR------VLADHVRTLTFAL 313
Query: 353 ADGVIPSNVKAGYLARLLIRKSIRHLKELGLEVPL----SEIVALHIKELHKTFPEFKEM 408
ADG +P+N GY+ R ++R+ R+ ++ + P+ S + I ++ FPE +
Sbjct: 314 ADGGVPNNEGRGYVLRRILRRGARYARKY-MNYPIGNFFSTLAPTLISQVQDIFPELAKD 372
Query: 409 EDVILEIIDLEEKKYSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELV 468
+ EI+D EE +++TL RG L + + K + +++ Y+++G +L
Sbjct: 373 PAFLFEILDEEEASFAKTLDRGERLFEKYASAASKTESKTLDGKQVWRLYDTYGFPVDLT 432
Query: 469 KEIAEKEGIKVHVPDNFYSIVAKEAEKEKEEKEEEVVDFELVK-------DLPETRTLYY 521
+ +AE++G+K+ P F AK+ E ++ + +L+K +L + +
Sbjct: 433 ELMAEEQGLKIDGP-GFEK--AKQESYEASKRGGKRTKSDLIKLNVHELSELNDAKVPKT 489
Query: 522 EDPF---MKEFEARVLRVIGD--------------WIVLDQTAFYPEGGGQPYDTGVLFV 564
D F E +L++ I+LD+T FY E GGQ YDTG + +
Sbjct: 490 NDEFKYGSANVEGTILKLHDGTNFVDEITEPGKKYGIILDKTCFYAEQGGQEYDTGKIVI 549
Query: 565 -NGSEVKVTNVQKVGKVIVHKVE-NPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGA 622
+ +E V NVQ + H G G ++ D RR +HTGTH+L A
Sbjct: 550 DDAAEFNVENVQLYNGFVFHTGSLEEGKLSVGDKIIASFDELRRFPIKNNHTGTHILNFA 609
Query: 623 LVRVLGKHVWQAGSQLTTDWARLDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPR 682
L LG V Q GS + + R D SH K +S+EEL+++E + N + E+ +V ++ +P
Sbjct: 610 LKETLGNDVDQKGSLVAPEKLRFDFSHKKAVSNEELKKVEDICNEQIKENLQVFYKEIPL 669
Query: 683 TEAEQRYGFRLYQGGVVPGRVIRVVKI-------------EDW---DVQACGGTHLPSTG 726
A+ G R G P V RVV + E+W ++ CGGTH+ TG
Sbjct: 670 DLAKSIDGVRAVFGETYPDPV-RVVSVGKPIEELLANPANEEWTKYSIEFCGGTHVNKTG 728
Query: 727 LVGPIKILRTERIQDGVERIIFACGEAA------------------------IKEWQKER 762
+ IL I G+ RI+ G A IKE +K +
Sbjct: 729 DIKYFVILEESGIAKGIRRIVAVTGTEAFEAQRLAEQFAADLDAADKLPFSPIKE-KKLK 787
Query: 763 EILKKASQVLRVPPEKLPETAERFFNEWKEARKEVEKLKKELAKLLVYELEAKVQKVKEY 822
E+ K Q L + E ++F K + EV+ K+ K + E++ +Q +
Sbjct: 788 ELGVKLGQ-LSISVITKNELKQKFNKIEKAVKDEVKSRAKKENKQTLDEVKTFLQTNENA 846
Query: 823 EFIGEIVEGSMD--DLREAVERLK-----KPNRIVVLVSKEGYFAISVGDNVN------- 868
++ + ++ S + + EA+ +K K I +L + ++ G ++
Sbjct: 847 PYLVKFIDISPNAKAITEAINYMKSNDSVKDKSIYLLAGNDPEGRVAHGCYISNAALAKG 906
Query: 869 LNANDLAKKLTSIAGGGGGGRKDVAQGRIKDVSKAKEAIESIVKL 913
++ + LAKK++SI GG GG+ +V QG + K+A++ + L
Sbjct: 907 IDGSALAKKVSSIIGGKAGGKGNVFQGMGDKPAAIKDAVDDLESL 951
>gi|6324911 Cytoplasmic alanyl-tRNA synthetase gene; Ala1p [Saccharomyces
cerevisiae] >gi|1711623|sp|P40825|SYAC_YEAST ALANYL-TRNA
SYNTHETASE, CYTOPLASMIC (ALANINE--TRNA LIGASE) (ALARS)
>gi|2118342|pir||S62065 alanine--tRNA ligase (EC
6.1.1.7), cytosolic - yeast (Saccharomyces cerevisiae)
>gi|1163069|emb|CAA89980.1| (Z49821) ALA1 [Saccharomyces
cerevisiae] >gi|1420729|emb|CAA99658.1| (Z75243) ORF
YOR335c [Saccharomyces cerevisiae]
Length = 958
Score = 230 bits (580), Expect = 6e-59
Identities = 250/1000 (25%), Positives = 418/1000 (41%), Gaps = 190/1000 (19%)
Query: 52 GIPKKYTLDEMREKFLKFFEKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISG 111
G +K+T +R FL +F+ E H VK PV+P +L A + ++P + G
Sbjct: 4 GDKQKWTATNVRNTFLDYFKSKE---HKFVKSSPVVPFDDPTLLFANAGMNQYKP-IFLG 59
Query: 112 EADPPANPLVI-----SQPSIR----FTDIDNVGITGRHFTIFEMMAHHAFNYPGKP--- 159
DP ++ + SQ IR D+++VG H T FEM+ + +F K
Sbjct: 60 TVDPASDFYTLKRAYNSQKCIRAGGKHNDLEDVGKDSYHHTFFEMLGNWSFGDYFKKEAI 119
Query: 160 ---------IYWI------------DETVELAFEFFTKELKMK---PEDITF----KENP 191
+Y I DE + L + +EL P+D K+N
Sbjct: 120 TYSWTLLTEVYGIPKDRLYVTYFEGDEKLGLEPDTEARELWKNVGVPDDHILPGNAKDNF 179
Query: 192 WAGG--GNAGPAFEVLYRG-----------------LEVATLVFMQYKKAPENAPEDQVV 232
W G G GP E+ Y LEV LVF+Q+ + + + +
Sbjct: 180 WEMGDQGPCGPCSEIHYDRIGGRNAASLVNMDDPDVLEVWNLVFIQFNREQDGSLK---- 235
Query: 233 IIKGDRYVPMETKVVDTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERIL 292
P+ K +DTG G ERLV + Q + YD V PL E+I E +
Sbjct: 236 --------PLPAKHIDTGMGFERLVSVLQDVRSNYDTD---VFTPL-----FERIQE--I 277
Query: 293 MENSRLAGMFDIEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFML 352
+G F D + ++ A R +ADH + LTF L
Sbjct: 278 TSVRPYSGNFGENDK------------------DGIDTAYR------VLADHVRTLTFAL 313
Query: 353 ADGVIPSNVKAGYLARLLIRKSIRHLKELGLEVPL----SEIVALHIKELHKTFPEFKEM 408
ADG +P+N GY+ R ++R+ R+ ++ + P+ S + I ++ FPE +
Sbjct: 314 ADGGVPNNEGRGYVLRRILRRGARYARKY-MNYPIGNFFSTLAPTLISQVQDIFPELAKD 372
Query: 409 EDVILEIIDLEEKKYSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELV 468
+ EI+D EE +++TL RG L + + K + +++ Y+++G +L
Sbjct: 373 PAFLFEILDEEEASFAKTLDRGERLFEKYASAASKTESKTLDGKQVWRLYDTYGFPVDLT 432
Query: 469 KEIAEKEGIKVHVPD----NFYSIVAKEAEKEKEEKEEEVVDFELVKDLPETRTLYYEDP 524
+ +AE++G+K+ P S A + +K++ + ++ + +L + + D
Sbjct: 433 ELMAEEQGLKIDGPGFEKAKQESYEASKRGGKKDQSDLIKLNVHELSELNDAKVPKTNDE 492
Query: 525 F---MKEFEARVLRVIGD--------------WIVLDQTAFYPEGGGQPYDTGVLFV-NG 566
F E +L++ I+LD+T FY E GGQ YDTG + + +
Sbjct: 493 FKYGSANVEGTILKLHDGTNFVDEITEPGKKYGIILDKTCFYAEQGGQEYDTGKIVIDDA 552
Query: 567 SEVKVTNVQKVGKVIVHKVE-NPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVR 625
+E V NVQ + H G G ++ D RR +HTGTH+L AL
Sbjct: 553 AEFNVENVQLYNGFVFHTGSLEEGKLSVGDKIIASFDELRRFPIKNNHTGTHILNFALKE 612
Query: 626 VLGKHVWQAGSQLTTDWARLDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEA 685
LG V Q GS + + R D SH K +S+EEL+++E + N + E+ +V ++ +P A
Sbjct: 613 TLGNDVDQKGSLVAPEKLRFDFSHKKAVSNEELKKVEDICNEQIKENLQVFYKEIPLDLA 672
Query: 686 EQRYGFRLYQGGVVPGRVIRVVKI-------------EDW---DVQACGGTHLPSTGLVG 729
+ G R G P V RVV + E+W ++ CGGTH+ TG +
Sbjct: 673 KSIDGVRAVFGETYPDPV-RVVSVGKPIEELLANPANEEWTKYSIEFCGGTHVNKTGDIK 731
Query: 730 PIKILRTERIQDGVERIIFACGEAAIKEWQKEREILKKASQVLRVP-----PEKLPETAE 784
IL I G+ RI+ G A + + + ++P +KL E
Sbjct: 732 YFVILEESGIAKGIRRIVAVTGTEAFEAQRLAEQFAADLDAADKLPFSPIKEKKLKELGV 791
Query: 785 RF---------FNEWKEARKEVEK-LKKELAKLLVYELEAKVQKVKEYEFIGE------- 827
+ NE K+ ++EK +K E+ E + + +VK + E
Sbjct: 792 KLGQLSISVITKNELKQKFNKIEKAVKDEVKSRAKKENKQTLDEVKTFFETNENAPYLVK 851
Query: 828 --IVEGSMDDLREAVERLK-----KPNRIVVLVSKEGYFAISVGDNVN-------LNAND 873
+ + + EA+ +K K I +L + ++ G ++ ++ +
Sbjct: 852 FIDISPNAKAITEAINYMKSNDSVKDKSIYLLAGNDPEGRVAHGCYISNAALAKGIDGSA 911
Query: 874 LAKKLTSIAGGGGGGRKDVAQGRIKDVSKAKEAIESIVKL 913
LAKK++SI GG GG+ +V QG + K+A++ + L
Sbjct: 912 LAKKVSSIIGGKAGGKGNVFQGMGDKPAAIKDAVDDLESL 951
>sp|P00957|SYA_ECOLI ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|7428468|pir||SYECAT alanine--tRNA ligase (EC
6.1.1.7) [validated] - Escherichia coli
>gi|1789048|gb|AAC75739.1| (AE000353) alanyl-tRNA
synthetase [Escherichia coli K12]
>gi|1800083|dbj|BAA16559.1| (D90892) ALANYL-TRNA
SYNTHETASE (EC 6.1.1.7) (ALANINE--TRNA LIGASE) (ALARS).
[Escherichia coli]
Length = 876
Score = 229 bits (579), Expect = 8e-59
Identities = 233/930 (25%), Positives = 380/930 (40%), Gaps = 149/930 (16%)
Query: 61 EMREKFLKFFEKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPANPL 120
E+R+ FL FF H V ++P +L A + F+ V G +
Sbjct: 7 EIRQAFLDFFHSKG---HQVVASSSLVPHNDPTLLFTNAGMNQFKD-VFLGLDKRNYSRA 62
Query: 121 VISQPSIR----FTDIDNVGITGRHFTIFEMMAHHAFN---------------------- 154
SQ +R D++NVG T RH T FEM+ + +F
Sbjct: 63 TTSQRCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKHDAIQFAWELLTSEKWFA 122
Query: 155 YPGKPIYWID--ETVELAFEFFTKELKMKPEDIT----------FKENPWAGG--GNAGP 200
P K W+ E+ + A+E + KE+ + E I +N W G G GP
Sbjct: 123 LP-KERLWVTVYESDDEAYEIWEKEVGIPRERIIRIGDNKGAPYASDNFWQMGDTGPCGP 181
Query: 201 AFEVLY-------------------RGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYVP 241
E+ Y R +E+ +VFMQ+ + + E P
Sbjct: 182 CTEIFYDHGDHIWGGPPGSPEEDGDRYIEIWNIVFMQFNRQADGTME------------P 229
Query: 242 METKVVDTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSRLAGM 301
+ VDTG GLER+ + Q + YD L
Sbjct: 230 LPKPSVDTGMGLERIAAVLQHVNSNYDIDL------------------------------ 259
Query: 302 FDIEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSNV 361
+ L + VA+ G + + K++R IADH ++ F++ADGV+PSN
Sbjct: 260 --------FRTLIQAVAKVTG-ATDLSNKSLR------VIADHIRSCAFLIADGVMPSNE 304
Query: 362 KAGYLARLLIRKSIRHLKELGL-EVPLSEIVALHIKELHKTFPEFKEMEDVILEIIDLEE 420
GY+ R +IR+++RH LG E ++V I + + K + + +++ EE
Sbjct: 305 NRGYVLRRIIRRAVRHGNMLGAKETFFYKLVGPLIDVMGSAGEDLKRQQAQVEQVLKTEE 364
Query: 421 KKYSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKVH 480
++++ TL+RG L+ E+AKL + E Y+++G +L ++ + IKV
Sbjct: 365 EQFARTLERGLALLDEELAKLSGDTLDG---ETAFRLYDTYGFPVDLTADVCRERNIKVD 421
Query: 481 VPDNFYSIVAKEAEKEKEEKEEEVVDFELVKDLPETRTLYYEDPFMKEFEARVLRVIGDW 540
+ + +E + E D+ + + D + L V G
Sbjct: 422 --EAGFEAAMEEQRRRAREASGFGADYNAMIRVDSASEFKGYDHLELNGKVTALFVDGKA 479
Query: 541 I-----------VLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTNVQKVGKVIVHKVE-NP 588
+ VLDQT FY E GGQ D G L V + QK G+ I H +
Sbjct: 480 VDAINAGQEAVVVLDQTPFYAESGGQVGDKGELKGANFSFAVEDTQKYGQAIGHIGKLAA 539
Query: 589 GLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTTDWARLDIS 648
G K G V+ +D RR + +H+ TH++ AL +VLG HV Q GS + R D S
Sbjct: 540 GSLKVGDAVQADVDEARRARIRLNHSATHLMHAALRQVLGTHVSQKGSLVNDKVLRFDFS 599
Query: 649 HYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFRLYQGGVVPGRVIRVVK 708
H + + EE+R +E L N + + + + A+ + L+ G +RV+
Sbjct: 600 HNEAMKPEEIRAVEDLVNTQIRRNLPIETNIMDLEAAKAKGAMALF--GEKYDERVRVLS 657
Query: 709 IEDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGEAAIKEWQKEREILKKA 768
+ D+ + CGGTH TG +G +I+ GV RI GE AI + + L +
Sbjct: 658 MGDFSTELCGGTHASRTGDIGLFRIISESGTAAGVRRIEAVTGEGAIATVHADSDRLSEV 717
Query: 769 SQVLRVPPEKLPETAERFFNEWKEARKEVEKLKKELAKLLVYELEAKVQKVKEYE-FIGE 827
+ +L+ L + ++ KE+++LK++ A L +K V + + E
Sbjct: 718 AHLLKGDSNNLADKVRSVLERTRQLEKELQQLKEQAAAQESANLSSKAIDVNGVKLLVSE 777
Query: 828 IVEGSMDDLREAVERLKKP--NRIVVLVS-KEGYFAISVGDNVN----LNANDLAKKLTS 880
+ LR V+ LK + I+VL + EG ++ G + + + A +L +
Sbjct: 778 LSGVEPKMLRTMVDDLKNQLGSTIIVLATVVEGKVSLIAGVSKDVTDRVKAGELIGMVAQ 837
Query: 881 IAGGGGGGRKDVAQGRIKDVSKAKEAIESI 910
GG GGGR D+AQ D + A+ S+
Sbjct: 838 QVGGKGGGRPDMAQAGGTDAAALPAALASV 867
>gb|AAA03208.1| (J01581) alanyl-tRNA synthetase [Escherichia coli]
Length = 876
Score = 229 bits (577), Expect = 1e-58
Identities = 232/930 (24%), Positives = 379/930 (39%), Gaps = 149/930 (16%)
Query: 61 EMREKFLKFFEKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPANPL 120
E+R+ FL FF RYP+ +L A + F+ V G +
Sbjct: 7 EIRQAFLDFFHSKGHQVVASSSRYPITD---PTLLFTNAGMNQFKD-VFLGLDKRNYSRA 62
Query: 121 VISQPSIR----FTDIDNVGITGRHFTIFEMMAHHAFN---------------------- 154
SQ +R D++NVG T RH T FEM+ + +F
Sbjct: 63 TTSQRCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKHDAIQFAWELLTSEKWFA 122
Query: 155 YPGKPIYWID--ETVELAFEFFTKELKMKPEDITF----KENPWAGG--------GNAGP 200
P K W+ E+ + A+E + KE+ + E I K P+A G G P
Sbjct: 123 LP-KERLWVTVYESDDEAYEIWEKEVGIPRERIIRINDNKGAPYASGNFWRMGGTGPCDP 181
Query: 201 AFEVLY-------------------RGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYVP 241
E+ Y R +E+ +VFMQ+ + + E P
Sbjct: 182 CTEIFYDHGDHIWGGPPGSPEEDGDRYIEIWNIVFMQFNRQADGTME------------P 229
Query: 242 METKVVDTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSRLAGM 301
+ VDTG GLER+ + Q + YD L
Sbjct: 230 LPKPSVDTGMGLERIAAVLQHVNSNYDIDL------------------------------ 259
Query: 302 FDIEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSNV 361
+ L + VA+ G + + K++R IADH ++ F++ADGV+PSN
Sbjct: 260 --------FRTLIQAVAKVTG-ATDLSNKSLR------VIADHIRSCAFLIADGVMPSNE 304
Query: 362 KAGYLARLLIRKSIRHLKELGL-EVPLSEIVALHIKELHKTFPEFKEMEDVILEIIDLEE 420
GY+ R +IR+++RH LG E ++V I + + K + + +++ EE
Sbjct: 305 NRGYVLRRIIRRAVRHGNMLGAKETFFYKLVGPLIDVMGSAGEDLKRQQAQVEQVLKTEE 364
Query: 421 KKYSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKVH 480
++++ TL+RG L+ E+AKL + E Y+++G +L ++ + IKV
Sbjct: 365 EQFARTLERGLALLDEELAKLSGDTLDG---ETAFRLYDTYGFPVDLTADVCRERNIKVD 421
Query: 481 VPDNFYSIVAKEAEKEKEEKEEEVVDFELVKDLPETRTLYYEDPFMKEFEARVLRVIGDW 540
+ + +E + E D+ + + D + L V G
Sbjct: 422 --EAGFEAAMEEQRRRAREASGFGADYNAMIRVDSASEFKGYDHLELNGKVTALFVDGKA 479
Query: 541 I-----------VLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTNVQKVGKVIVHKVE-NP 588
+ VLDQT FY E GGQ D G L V + QK G+ I H +
Sbjct: 480 VDAINAGQEAVVVLDQTPFYAESGGQVGDKGELKGANFSFAVEDTQKYGQAIGHIGKLAA 539
Query: 589 GLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTTDWARLDIS 648
G K G V+ +D RR + +H+ TH++ AL +VLG HV GS + R D S
Sbjct: 540 GSLKVGDAVQADVDEARRARIRLNHSATHLMHAALRQVLGTHVSHKGSLVNDKVLRFDFS 599
Query: 649 HYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFRLYQGGVVPGRVIRVVK 708
H + + EE+R +E L N ++ + + + A+ + L+ G +RV+
Sbjct: 600 HNEAMKPEEIRAVEDLVNTLIRRNLPIETNIMDLEAAKAKGAMALF--GEKYDERVRVLS 657
Query: 709 IEDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGEAAIKEWQKEREILKKA 768
+ D+ + CGGTH TG +G +I+ GV RI GE AI + + L +
Sbjct: 658 MGDFSTELCGGTHASRTGDIGLFRIISESGTAAGVRRIEAVTGEGAIATVHADSDRLSEV 717
Query: 769 SQVLRVPPEKLPETAERFFNEWKEARKEVEKLKKELAKLLVYELEAKVQKVKEYE-FIGE 827
+ +L+ L + ++ KE+++LK++ A L +K V + + E
Sbjct: 718 AHLLKGDSNNLADKVRSVLERTRQLEKELQQLKEQAAAQESANLSSKAIDVNGVKLLVSE 777
Query: 828 IVEGSMDDLREAVERLKKP--NRIVVLVS-KEGYFAISVGDNVN----LNANDLAKKLTS 880
+ LR V+ LK + I+VL + EG ++ G + + + A +L +
Sbjct: 778 LSGVEPKMLRTMVDDLKNQLGSTIIVLATVVEGKVSLIAGVSKDVTDRVKAGELIGMVAQ 837
Query: 881 IAGGGGGGRKDVAQGRIKDVSKAKEAIESI 910
GG GGGR D+AQ D + A+ S+
Sbjct: 838 QVGGKGGGRPDMAQAGGTDAAALPAALASV 867
>gb|AAG23689.1|AF297520_1 (AF297520) alanyl-tRNA synthase [Haemophilus ducreyi]
Length = 783
Score = 219 bits (551), Expect = 2e-55
Identities = 188/727 (25%), Positives = 330/727 (44%), Gaps = 99/727 (13%)
Query: 195 GGNAGPAFEVLYRGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYVPMETKVVDTGYGLE 254
GG G A E R +EV +VFMQ+ + + + VDTG GLE
Sbjct: 103 GGLPGTAEEDGDRYIEVWNIVFMQFNRQADGT------------LAKLPKPSVDTGMGLE 150
Query: 255 RLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSRLAGMFDIEDMGDLKLLR 314
R+ + Q + Y+ I + ++ E + L + D+++
Sbjct: 151 RMTAVMQHVNSNYET----------------DIFQTLIKEVATLLHVADLDN-------- 186
Query: 315 KKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSNVKAGYLARLLIRKS 374
K++R IADH +A ++++ DGVIPSN GY+ R +IR++
Sbjct: 187 ---------------KSLR------VIADHIRACSYLIVDGVIPSNEGRGYVLRRIIRRA 225
Query: 375 IRHLKELGL-EVPLSEIVALHIKELHKTFPEFKEMEDVILEIIDLEEKKYSETLKRGSDL 433
+RH LG E ++V K + + + + I + + EE++++ TL+RG L
Sbjct: 226 VRHGNLLGAKEAFFYKLVPTLAKVMGQAGEILTDKQSYIQKTLKTEEEQFARTLERGLAL 285
Query: 434 VRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKVHVPDNFYSIVAKEA 493
+ + K++ + +S E Y+++G +L ++ + I + +F + +
Sbjct: 286 LEEALTKVENQTLSG---EVAFKLYDTYGFPLDLTADVCRERDIVIDEA-SFEIEMTAQR 341
Query: 494 EKEKEEKEEEVVDFELVKDLPETRTLYYEDPFMKEFEARVLRVIGDW------------- 540
E+ K ++K ET + Y+ EA+V+ + +
Sbjct: 342 ERAKSSSNFGADYNSVIKVEAETAFIGYD---CFNAEAKVIALFSNGQAVDKVQSGESAV 398
Query: 541 IVLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTNVQKVGKVIVHKVEN-PGLFKEGMEVRG 599
+VLD+T FY E GGQ D+G++ + V + QK G+V H + G G +
Sbjct: 399 VVLDKTPFYAEMGGQVGDSGLITTAFCQFAVADTQKYGQVFGHIGQVVSGSLAIGDIISA 458
Query: 600 RIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTTDWARLDISHYKRISDEELR 659
++D RR +H+ TH+L AL +VLG+HV Q GS ++ + R D S + +S +L
Sbjct: 459 QVDIARRQAITANHSATHLLHSALRQVLGEHVVQKGSLVSENVLRFDFSQSQAVSKAQLE 518
Query: 660 EIERLANRIVMEDRKVTWEWLPRTEAEQRYGFRLYQGGVVPGRVIRVVKIEDWDVQACGG 719
EIER+ NR + ++ VT E + A+++ L+ G G V+RVV + D+ ++ CGG
Sbjct: 519 EIERIVNRQIRQNLAVTIETMDIETAKEKGTVALF--GEKYGDVVRVVGMTDFSIELCGG 576
Query: 720 THLPSTGLVGPIKILRTERIQDGVERIIFACGEAAIKEWQKEREILKKASQVLRVPPEKL 779
TH+ TG +G K++ + G+ R+ E AI +++I+ +++++L+ L
Sbjct: 577 THVKHTGEIGLFKLISESAVAAGIRRVEALTAENAINWLHNQQKIIHQSAELLKTDSLSL 636
Query: 780 PETAERFFNEWKEARKEVEKLKKELAKLLVYELEAKVQKVKEYEFIGEIVEG-SMDDLRE 838
+ + ++ K KE++ K +LA EL +V ++ + + +EG LR
Sbjct: 637 VDKIYQLQDKIKRNEKELQHFKDKLAAQAGAELAKQVVQINGINVVIQKLEGIESKSLRT 696
Query: 839 AVERLKKPNRIVVLVSKEGYFAISVGDNVNL------------NANDLAKKLTSIAGGGG 886
V+ LK V++V F D VNL NA +L + GG G
Sbjct: 697 MVDDLKNQLSSVIVV-----FGSVSADKVNLIVGVTKDLSNKVNAGELVGLIAQQVGGKG 751
Query: 887 GGRKDVA 893
GGR D+A
Sbjct: 752 GGRPDMA 758
>pir||E71476 alanine--tRNA ligase (EC 6.1.1.7) - Chlamydia trachomatis
(serotype D, strain UW3/Cx)
Length = 924
Score = 215 bits (543), Expect = 1e-54
Identities = 229/930 (24%), Positives = 403/930 (42%), Gaps = 158/930 (16%)
Query: 50 KPGIPKKYTLDEMREKFLKFFEKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVI 109
K G+P + +R FLKF+ H V PV P +L A + F+ +
Sbjct: 45 KNGLPM--LSNTLRSNFLKFYANRN---HTPVASSPVFPHNDPSILFTNAGMNQFKN-IF 98
Query: 110 SGEADPPANPLVISQPSIR----FTDIDNVGITGRHFTIFEMMAHHAF------------ 153
G+ SQ IR D++NVG T RH T FEM+ + +F
Sbjct: 99 LGKEQTSYTRATTSQKCIRAGGKHNDLENVGHTSRHLTFFEMLGNFSFGDYFKQDAISFA 158
Query: 154 --------NYPGKPIY-WIDETVELAFEFFTKELKMKPED----ITFKENPW--AGGGNA 198
N+ IY + E + AF + K L P D +T K+N W A G
Sbjct: 159 WEVSLSIFNFDPDFIYATVHEKDDEAFALWEKYL---PTDRIFRLTDKDNFWSMADTGPC 215
Query: 199 GPAFEVLY-------------------RGLEVATLVFMQYKKAPENAPEDQVVIIKGDRY 239
G E+L+ R LE LVFM++ + +
Sbjct: 216 GFCSELLFDRGEKFGKAASPLEDVDGERFLEYWNLVFMEFNRTSDGT------------L 263
Query: 240 VPMETKVVDTGYGLERLVWMSQGTPTAYDA-VLGYVVEPLKRMAGVEKIDERILMENSRL 298
+ ++ K VDTG GLERLV + T T ++A VL +++ ++ ++G
Sbjct: 264 LALQKKCVDTGAGLERLVSLLAETETVFEADVLRHLISKIENLSGTT------------- 310
Query: 299 AGMFDIEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIP 358
S E + A IADH ++L+F +ADG++P
Sbjct: 311 ------------------------YSPTEAKGAA-----FRVIADHIRSLSFAIADGLLP 341
Query: 359 SNVKAGYLARLLIRKSIRHLKELGLEVP-LSEIVALHIKELHKTFPEFKEMEDVILEIID 417
N + GY+ R ++R+++ + K LG P L+++V + + + +PE I E++
Sbjct: 342 GNTERGYVLRKILRRAVNYGKRLGFNRPFLADVVPSLVDVMGEAYPELSASVTQIQEVLT 401
Query: 418 LEEKKYSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGI 477
EE+ + +TL+RG +L+++ + ++I E +++GL + + +A+
Sbjct: 402 TEEEHFFKTLQRGGNLLQQVLKS--SASSAKISGEDAFKLKDTYGLPIDEIALLAKDYNY 459
Query: 478 KVHVPDNFYSIVAKEAEKEKEEKEEEVVDFELV-KDLPETRT---LYYEDPFMKEFEARV 533
+ + D F + + E+ ++ ++ D + V +DL T T + Y+ F +
Sbjct: 460 AIDM-DTFEKLEVEAKERSRKNTKKTKNDSDSVFQDLDPTNTSEFIGYDTLSCDTFIEGI 518
Query: 534 LRVI--------GDW--IVLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTNV--QKVGKVI 581
++ GD I+L T FY GGQ D+G +F V++ K G ++
Sbjct: 519 IKYNEIASSLEEGDEGAIILRTTPFYAGKGGQIGDSGEIFCESGTFLVSHTIAPKAGLIV 578
Query: 582 VHKVENPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTTD 641
+ G M V +++ + R + +HTG H+L AL LG+H+ QAGS + +
Sbjct: 579 HLGKLSQGSLTTTMAVTAQVNQNLRKKTANNHTGCHLLHKALEMTLGEHIRQAGSYVDSQ 638
Query: 642 WARLDISHYKRISDEELREIERLANRIVMEDRKVT------WEWLPRTEAEQRYGFRLYQ 695
RLD +H K +S E+L IE L N + E+ VT + + +E +Q +G +
Sbjct: 639 KIRLDFTHNKALSPEDLLAIETLVNEKIRENDPVTIREVLYSDVMSSSEIKQFFGDKY-- 696
Query: 696 GGVVPGRVIRVVKIEDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGEAAI 755
G ++RVV + + CGGTH +TG +G +I + + G+ RI GE A
Sbjct: 697 -----GDIVRVVS-AGFSHELCGGTHAQATGDIGYFRITKEHAVATGIRRIEATTGEDAE 750
Query: 756 KEWQKEREILKKASQVLRVPPEKLPETAERFFNEWKEARKEVEKLKKELAKLLVYELEAK 815
+++ L + + V++ P +++ E K+ K+V L+ +L + V L
Sbjct: 751 NIAREQDVDLNEIATVIQSPKDQILVKIRSVMEEKKDLAKQVADLENQLVQQQVKTLLTS 810
Query: 816 VQKVKEYEFIGEIV---EGS-MDDLREAVERLKKPNRIVVLVSKEG--YFAIS-VGDNV- 867
+K+ + ++ + EG + A+ + N I + ++++ Y +S V D++
Sbjct: 811 CEKICDTSYLVYYLTEEEGQRIQHYANAIHKEIPTNFISLWITEKNGRYIVLSRVSDDLT 870
Query: 868 --NLNANDLAKKLTSIAGGGGGGRKDVAQG 895
+ A+ L +L + GG GG+ AQG
Sbjct: 871 KRGVQAHTLLAELLAPYGGRCGGKAISAQG 900
>sp|O84754|SYA_CHLTR ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|6578113|gb|AAC68344.2| (AE001346) Alanyl tRNA
Synthetase [Chlamydia trachomatis]
Length = 875
Score = 215 bits (542), Expect = 2e-54
Identities = 226/918 (24%), Positives = 398/918 (42%), Gaps = 156/918 (16%)
Query: 62 MREKFLKFFEKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPANPLV 121
+R FLKF+ H V PV P +L A + F+ + G+
Sbjct: 6 LRSNFLKFYANRN---HTPVASSPVFPHNDPSILFTNAGMNQFKN-IFLGKEQTSYTRAT 61
Query: 122 ISQPSIR----FTDIDNVGITGRHFTIFEMMAHHAF--------------------NYPG 157
SQ IR D++NVG T RH T FEM+ + +F N+
Sbjct: 62 TSQKCIRAGGKHNDLENVGHTSRHLTFFEMLGNFSFGDYFKQDAISFAWEVSLSIFNFDP 121
Query: 158 KPIY-WIDETVELAFEFFTKELKMKPED----ITFKENPW--AGGGNAGPAFEVLY---- 206
IY + E + AF + K L P D +T K+N W A G G E+L+
Sbjct: 122 DFIYATVHEKDDEAFALWEKYL---PTDRIFRLTDKDNFWSMADTGPCGFCSELLFDRGE 178
Query: 207 ---------------RGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYVPMETKVVDTGY 251
R LE LVFM++ + + + ++ K VDTG
Sbjct: 179 KFGKAASPLEDVDGERFLEYWNLVFMEFNRTSDGT------------LLALQKKCVDTGA 226
Query: 252 GLERLVWMSQGTPTAYDA-VLGYVVEPLKRMAGVEKIDERILMENSRLAGMFDIEDMGDL 310
GLERLV + T T ++A VL +++ ++ ++G
Sbjct: 227 GLERLVSLLAETETVFEADVLRHLISKIENLSGTT------------------------- 261
Query: 311 KLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSNVKAGYLARLL 370
S E + A IADH ++L+F +ADG++P N + GY+ R +
Sbjct: 262 ------------YSPTEAKGAA-----FRVIADHIRSLSFAIADGLLPGNTERGYVLRKI 304
Query: 371 IRKSIRHLKELGLEVP-LSEIVALHIKELHKTFPEFKEMEDVILEIIDLEEKKYSETLKR 429
+R+++ + K LG P L+++V + + + +PE I E++ EE+ + +TL+R
Sbjct: 305 LRRAVNYGKRLGFNRPFLADVVPSLVDVMGEAYPELSASVTQIQEVLTTEEEHFFKTLQR 364
Query: 430 GSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKVHVPDNFYSIV 489
G +L+++ + ++I E +++GL + + +A+ + + D F +
Sbjct: 365 GGNLLQQVLKS--SASSAKISGEDAFKLKDTYGLPIDEIALLAKDYNYAIDM-DTFEKLE 421
Query: 490 AKEAEKEKEEKEEEVVDFELV-KDLPETRT---LYYEDPFMKEFEARVLRVI-------- 537
+ E+ ++ ++ D + V +DL T T + Y+ F +++
Sbjct: 422 VEAKERSRKNTKKTKNDSDSVFQDLDPTNTSEFIGYDTLSCDTFIEGIIKYNEIASSLEE 481
Query: 538 GDW--IVLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTNV--QKVGKVIVHKVENPGLFKE 593
GD I+L T FY GGQ D+G +F V++ K G ++ + G
Sbjct: 482 GDEGAIILRTTPFYAGKGGQIGDSGEIFCESGTFLVSHTIAPKAGLIVHLGKLSQGSLTT 541
Query: 594 GMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTTDWARLDISHYKRI 653
M V +++ + R + +HTG H+L AL LG+H+ QAGS + + RLD +H K +
Sbjct: 542 TMAVTAQVNQNLRKKTANNHTGCHLLHKALEMTLGEHIRQAGSYVDSQKIRLDFTHNKAL 601
Query: 654 SDEELREIERLANRIVMEDRKVT------WEWLPRTEAEQRYGFRLYQGGVVPGRVIRVV 707
S E+L IE L N + E+ VT + + +E +Q +G + G ++RVV
Sbjct: 602 SPEDLLAIETLVNEKIRENDPVTIREVLYSDVMSSSEIKQFFGDKY-------GDIVRVV 654
Query: 708 KIEDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGEAAIKEWQKEREILKK 767
+ + CGGTH +TG +G +I + + G+ RI GE A +++ L +
Sbjct: 655 S-AGFSHELCGGTHAQATGDIGYFRITKEHAVATGIRRIEATTGEDAENIAREQDVDLNE 713
Query: 768 ASQVLRVPPEKLPETAERFFNEWKEARKEVEKLKKELAKLLVYELEAKVQKVKEYEFIGE 827
+ V++ P +++ E K+ K+V L+ +L + V L +K+ + ++
Sbjct: 714 IATVIQSPKDQILVKIRSVMEEKKDLAKQVADLENQLVQQQVKTLLTSCEKICDTSYLVY 773
Query: 828 IV---EGS-MDDLREAVERLKKPNRIVVLVSKEG--YFAIS-VGDNV---NLNANDLAKK 877
+ EG + A+ + N I + ++++ Y +S V D++ + A+ L +
Sbjct: 774 YLTEEEGQRIQHYANAIHKEIPTNFISLWITEKNGRYIVLSRVSDDLTKRGVQAHTLLAE 833
Query: 878 LTSIAGGGGGGRKDVAQG 895
L + GG GG+ AQG
Sbjct: 834 LLAPYGGRCGGKAISAQG 851
>sp|Q9Z714|SYA_CHLPN ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|7437631|pir||H72023 alanine--tRNA ligase (EC
6.1.1.7) - Chlamydophila pneumoniae (strains CWL029 and
AR39) >gi|4377211|gb|AAD19030.1| (AE001669) Alanyl tRNA
Synthetase [Chlamydophila pneumoniae CWL029]
>gi|7189887|gb|AAF38754.1| (AE002255) alanyl-tRNA
synthetase [Chlamydophila pneumoniae AR39]
>gi|8979266|dbj|BAA99100.1| (AP002548) alanyl tRNA
synthetase [Chlamydophila pneumoniae J138]
Length = 872
Score = 213 bits (536), Expect = 9e-54
Identities = 229/930 (24%), Positives = 394/930 (41%), Gaps = 183/930 (19%)
Query: 62 MREKFLKFFEKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPANPLV 121
+R FLKF+ H + PV P +L A + F+ ++ E +
Sbjct: 6 IRSNFLKFYANRH---HTILPSSPVFPHNDPSILFTNAGMNQFKDIFLNKEKVSYSRATT 62
Query: 122 ISQPSIR----FTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFEFFTKE 177
SQ IR D+DNVG T RH T FEM+ + +F Y+ E + A+E
Sbjct: 63 -SQKCIRAGGKHNDLDNVGHTSRHLTFFEMLGNFSFGD-----YFKAEAIAFAWEVSLSV 116
Query: 178 LKMKPEDI---------------------------TFKENPW--AGGGNAGPAFEVLY-- 206
PE I T K+N W A G G E+L+
Sbjct: 117 FNFNPEGIYATVHEKDDEAFALWEAYLPTDRIFRLTDKDNFWSMANTGPCGYCSELLFDR 176
Query: 207 -----------------RGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYVPMETKVVDT 249
R LE LVFM++ + E + + + K VDT
Sbjct: 177 GPSFGNASSPLDDTDGERFLEYWNLVFMEFNRTSEGS------------LLALPNKHVDT 224
Query: 250 GYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSRLAG-MFDIEDMG 308
G GLERLV + GT T ++A + ++ + +L+G ++ +D G
Sbjct: 225 GAGLERLVSLIAGTHTVFEA----------------DVLRELIAKTEQLSGKVYHPDDSG 268
Query: 309 DLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSNVKAGYLAR 368
A R IADH ++L+F +ADG++P N + GY+ R
Sbjct: 269 ---------------------AAFR------VIADHVRSLSFAIADGLLPGNTERGYVLR 301
Query: 369 LLIRKSIRHLKELGLEVP-LSEIVALHIKELHKTFPEFKEMEDVILEIIDLEEKKYSETL 427
++R+S+ + + LG P L+EIV + + +PE K I +++ LEE+ + +TL
Sbjct: 302 KILRRSVNYGRRLGFRNPFLAEIVPSLADAMGEAYPELKNSLSQIQKVLTLEEESFFKTL 361
Query: 428 KRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKVHVPDNFYS 487
RG +L+++ + S I E +++G+ + + +A+ V + D F+
Sbjct: 362 DRGGNLLQQVLK--SSSSSSCISGEDAFKLKDTYGMPIDEISLLAKDYDYSVDM-DTFHK 418
Query: 488 IVAKEAEKEKEEKEEEVVDFELVKDLPETRTLYYEDPFMKEF------------EARVLR 535
+ E+E +E+ + +V+ + ++Y E EF EA + +
Sbjct: 419 L-----EQEAKERSRK----NVVQSQGTSESIYNELHLTSEFIGYDHLSCDTFIEAIISK 469
Query: 536 --VIGDW-------IVLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTNV--QKVGKVIVHK 584
++ IVL + FY E GGQ D+G +F + VT+ K G ++ H
Sbjct: 470 DHIVSSLQEKQEGAIVLKVSPFYAEKGGQVGDSGEIFCSEGTFIVTHTTSPKAGLIVHHG 529
Query: 585 VENPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTTDWAR 644
+ G V +++ RR + +HT H+L AL LG H+ QAGS + R
Sbjct: 530 RISQGSLTVEAAVTAQVNRYRRKRIANNHTACHLLHKALEITLGDHIRQAGSYVDDTKIR 589
Query: 645 LDISHYKRISDEELREIERLANRIVMEDRKVT------WEWLPRTEAEQRYGFRLYQGGV 698
LD +H + IS E+L IE L N + E+ V + + +E +Q +G +
Sbjct: 590 LDFTHPQAISPEDLLCIETLVNESIRENEPVDIREALYSDVMNSSEIKQFFGDKY----- 644
Query: 699 VPGRVIRVVKIEDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGEAAIKEW 758
V+RVV + CGGTH +TG +G +I + + G+ RI GE A
Sbjct: 645 --SDVVRVVS-AGHSHELCGGTHAEATGDIGFFRITKEHAVAMGIRRIEAVTGEKAEATV 701
Query: 759 QKEREILKKASQVLRVPPEKLPETAERFFNEWKEARKEVEKLKKELAKLLVYELEAKVQK 818
++ E+L++ + +L+VP +++ +E K+ K + +L+ L + +L+ +
Sbjct: 702 HQQSEVLEEIATLLQVPRDQIVSRLTATLDERKQQDKRLNELENSLIQT---KLDKLIHN 758
Query: 819 VKEYE----FIGEIVEGSMDDLREAVERLKK--PNRIVVL--VSKEGYFAI--SVGDNV- 867
+ + + + E L++ + L + P +++ L K G + + V D++
Sbjct: 759 CHQRQGITCLVHHLAEHENHRLQQYAQCLHQRIPEKLISLWTTEKNGKYIVLSRVSDDLI 818
Query: 868 --NLNANDLAKKLTSIAGGGGGGRKDVAQG 895
++A DL K + + GG GG+ AQG
Sbjct: 819 TQGVHAQDLLKAVLTPCGGRWGGKDQSAQG 848
>sp|O13914|SYAC_SCHPO PROBABLE ALANYL-TRNA SYNTHETASE, CYTOPLASMIC (ALANINE--TRNA LIGASE)
(ALARS) >gi|7492368|pir||T38247 probable alanyl-trna
synthetase, cytoplasmic - fission yeast
(Schizosaccharomyces pombe) >gi|2330773|emb|CAB11162.1|
(Z98559) probable alanyl-trna synthetase, cytoplasmic
[Schizosaccharomyces pombe]
Length = 959
Score = 210 bits (530), Expect = 4e-53
Identities = 238/921 (25%), Positives = 397/921 (42%), Gaps = 171/921 (18%)
Query: 60 DEMREKFLKFFEKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPANP 119
+E+R FLK+FE H H V V+P +L A + F+P + G DP ++
Sbjct: 13 NEIRRTFLKYFEDHG---HTIVPSSSVIPYDDPTLLFANAGMNQFKP-IFLGTVDPSSDF 68
Query: 120 LVI-----SQPSIR----FTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELA 170
+ SQ IR D+++VG H T+FEM+ + +F Y+ E + +A
Sbjct: 69 AKLKRACDSQKCIRAGGKHNDLEDVGKDNYHHTMFEMLGNWSFGD-----YFKKEAIAMA 123
Query: 171 FEFFTKELKMKPEDI------------------------------------TFKENPWAG 194
++ T +K + + + K+N W
Sbjct: 124 WDLLTNVYGLKKDQLYVTYFGGHEESGLEPDLEARQLWLDIGIDESRVIPGSLKDNFWEM 183
Query: 195 G--GNAGPAFEVLYRGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYV-----PMETKVV 247
G G GP E+ Y + T+ + P +V I+ +R P+ + V
Sbjct: 184 GDQGPCGPCSEIHYDRIGNRTVPELVNMDDPNVLEIWNIVFIQFNREKDGSLRPLPNRHV 243
Query: 248 DTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSR-LAGMFDIED 306
DTG G ERLV + Q + YD V P+ KI E + N+R G ED
Sbjct: 244 DTGMGFERLVSVIQNKTSNYDT---DVFSPI-----FAKIQE---LTNARPYTGKMGDED 292
Query: 307 MGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSNVKAGYL 366
V+ ++ A R +ADH + LTF ++DG +P+N GY+
Sbjct: 293 ------------------VDGIDTAYR------VVADHVRTLTFAISDGGVPNNEGRGYV 328
Query: 367 ARLLIRKSIRHL-KELGLEVP--LSEIVALHIKELHKTFPEFKEMEDVILEIIDLEEKKY 423
R ++R+ R++ K+ G+ + S + ++++ FPE K D + E++D EE+ +
Sbjct: 329 LRRILRRGARYVRKKFGVPIGNFFSRLSLTVVEQMGDFFPELKRKVDDVRELLDEEEESF 388
Query: 424 SETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKVHVPD 483
S TL RG + + A KK + + YE++G +L +AE+ GIK+ P
Sbjct: 389 SRTLDRGEKMFEQYAAAAKKTPSKTLQGNDVWRLYETYGFPVDLTHLMAEEAGIKIDEP- 447
Query: 484 NFYSIVAKEAEKEKEEKE-----EEVVDFEL--------VKDLPET-------------- 516
F + A+ E K+ + ++++ ++ + D+PET
Sbjct: 448 GFEAAQARSKEISKQASKGGSSGDDLLVLDVHALGALSKMDDIPETDDVFKHNSVSLKSV 507
Query: 517 -RTLYYEDPFMKEFEA-RVLRVIGDWIVLDQTAFYPEGGGQPYDTGVLFVNG-SEVKVTN 573
+ +Y++ F K E +G ++LD+T FY E GGQ YDTG + ++G ++ +VTN
Sbjct: 508 IKGIYHKGGFQKSTEGFNSGEQLG--LLLDRTNFYAEQGGQEYDTGHIVIDGVADFRVTN 565
Query: 574 VQKVGKVIVHK-VENPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVW 632
VQ ++H G V D RR M +HT TH+L AL LG +
Sbjct: 566 VQVYAGYVLHTGFLEYGNLTVNDSVVCEYDEIRRWHLMNNHTVTHILNLALRNTLGDGID 625
Query: 633 QAGSQLTTDWARLDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFR 692
Q GS ++ + R D S+ I ++L +E N ++ ++ V + + ++A++ G R
Sbjct: 626 QRGSLVSQEKLRFDFSYKSSIPIDKLLLVENYCNNVIQDNLSVYSKEVALSKAKEINGLR 685
Query: 693 LYQGGVVPGRVIRVV-------------KIEDW---DVQACGGTHLPSTGLVGPIKILRT 736
G V P V RVV K DW ++ CGGTH +G + IL
Sbjct: 686 AVFGEVYPDPV-RVVCIGVDIDTLLQEPKKPDWTKYSIEFCGGTHCDKSGEIKDFVILEE 744
Query: 737 ERIQDGVERIIFACGEAAIKEWQKEREILKKASQVLRVPPEKLPETAERFFNEWKEARKE 796
I G+ RI+ A + + E + +++ EK+P F+ KEA E
Sbjct: 745 NGIAKGIRRIVAVTSTEANRVSRLANEFDARIAKL-----EKMP------FSPAKEA--E 791
Query: 797 VEKLKKELAKLLVYELEAKVQKVKEYEFIGEIVEGSMDDLR--EAVERLKKPNRIVVLVS 854
++K+ +L+KL+V A V+K E I +I + + ++ A E+ K+ +V
Sbjct: 792 LKKISVDLSKLVV----AAVRKHAMKERIAKITKQVQEHVKAINAAEQ-KEVVNVVTEYF 846
Query: 855 KEGYFAISVGDNVNLNANDLA 875
KE V V ++AN A
Sbjct: 847 KENPDMSFVVAKVPISANPKA 867
>sp|P21894|SYA_BOMMO ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|68535|pir||SYMTAT alanine--tRNA ligase (EC 6.1.1.7)
- silkworm >gi|155955|gb|AAA27821.1| (M55993) transfer
RNA-Ala synthetase [Bombyx mori]
Length = 967
Score = 202 bits (509), Expect = 1e-50
Identities = 251/1003 (25%), Positives = 420/1003 (41%), Gaps = 204/1003 (20%)
Query: 58 TLDEMREKFLKFFEKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPA 117
T +E+R+ F+ FF K H V +P +L A + F+P + G DP +
Sbjct: 6 TGNEIRKTFIDFFIKKG---HKYVHSSSTIPLDDPTLLFANAGMNQFKP-IFLGSVDPNS 61
Query: 118 NP-----LVISQPSIR----FTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVE 168
+ +V +Q IR D+D+VG H T FEMM + +F Y+ E
Sbjct: 62 DMAQYIRVVNTQKCIRAGGKHNDLDDVGKDVYHHTFFEMMGNWSFGD-----YFKKEICA 116
Query: 169 LAFEFFTKELKMKPEDI------------------------------------TFKENPW 192
A+E T K+ E + + K+N W
Sbjct: 117 WAWELLTDVFKLSRERLYVTYFEGDPSSGLEPDLECRNIWLNLGVPEAHILPGSMKDNFW 176
Query: 193 AGG--GNAGPAFEVLYRGL---EVATLVFMQYKKAPENAPEDQVVIIKGDRYVP-----M 242
G G GP E+ Y + E A LV M P+ +V I+ +R +
Sbjct: 177 EMGETGPCGPCSELHYDRIGDREAAHLVNMD---DPDVLEIWNLVFIQFNRETDGSLKLL 233
Query: 243 ETKVVDTGYGLERLVWMSQGTPTAYDAVLGY-VVEPLKRMAGVEKIDERILMENSRLAGM 301
TK +D G GLERLV + Q YD + + ++ GV
Sbjct: 234 PTKHIDCGLGLERLVSVIQNKRANYDTDFFMPIFKAIENATGV----------------- 276
Query: 302 FDIEDMGDLKLLRKKVAEKVGIS-VEELEKAIRPYELIYAIADHTKALTFMLADGVIPSN 360
+ + KVG+ V+ ++ A R +ADH + LT L+DG P N
Sbjct: 277 -------------RPYSGKVGVDDVDGIDMAYR------VLADHARTLTIALSDGGCPDN 317
Query: 361 VKAGYLARLLIRKSIRHLKELGLEVP--LSEIVALHIKELHKTFPEFKEMEDVILEIIDL 418
GY+ R ++R+++R+ E P +V ++ L FPE K+ D I+ +I+
Sbjct: 318 TGRGYVLRRILRRAVRYASEKLNAKPGFFGSLVYTVVELLGDVFPEIKKDPDSIVHVINE 377
Query: 419 EEKKYSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIK 478
EE ++ +TL RG +L+ R I KL +P + Y+++G +L + + E++G+
Sbjct: 378 EEVQFLKTLLRGRNLLYRTIEKLNNS--KTLPGDVAWRLYDTYGFPIDLTQLMCEEKGLN 435
Query: 479 VHVPDNFYSIVAKEAEKEKEEK---EEEVV--DFELVKDLPETR---------------- 517
V + Y KE++ + K +E+++ D + L +T
Sbjct: 436 VDMEG--YEKSRKESQLVSQGKAAGQEDLIALDVHAISHLQDTGIPATDDSPKYNYLPSS 493
Query: 518 ----TLYYEDPFM---------KEFEARVLRVIGDWIVLDQTAFYPEGGGQPYDTGVLFV 564
LY P KEF + + ++LD+T+FY E GGQ +D G +
Sbjct: 494 TDKDALYTFAPCTAKIVALRKNKEFVSEISSGQECGVILDRTSFYAEQGGQIFDEGYMVK 553
Query: 565 NGSEV---KVTNVQKVGKVIVHKVENPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMG 621
E V NVQ G ++H + G+ K G + ID +RR M +HTGTHVL
Sbjct: 554 IDDETVEFTVKNVQVKGGYVLHAGKVEGILKVGDTLSLHIDTERRRLVMNNHTGTHVLNN 613
Query: 622 ALVRVLGKHVWQAGSQLTTDWARLDISHYKRISDEELREIERLANRIVMEDRKVTWEWLP 681
L +VLG Q GS + D R D ++ ++ +++++ E I+ +++ V +
Sbjct: 614 VLRKVLGNDSDQRGSLVMPDRLRFDFTNKGPMTIKQIKDTENEIKEIIAKNKTVYANYTS 673
Query: 682 RTEAEQRYGFRLY--QGGVVPGRVIRV-VKIED------------WDVQACGGTHLPSTG 726
+EA++ G R + P RV+ V V +ED V+ CGG+HL T
Sbjct: 674 LSEAKKINGLRAMFDEHYPDPVRVVSVGVPVEDLIKNPDAPTGFETSVEFCGGSHLHRTS 733
Query: 727 LVGPIKILRTERIQDGVERIIFACGEAAIKEWQK----EREILKKAS------------Q 770
+G I+ E I G+ RI+ G AIK K E E+ A+ +
Sbjct: 734 HIGEYVIVSEEGIAKGIRRIVAVTGPEAIKAINKLSVLENEVNNVANFIKEQNESISHKE 793
Query: 771 VLRVPPEKLPETAERFFNEWK--EARKEVEKLKKEL-------AKLLVYELEAKVQKV-- 819
V + + E ++ + WK E R ++ LKK+L +++ ++ K +++
Sbjct: 794 VSKKIVDLTNEISQAQISYWKKDELRNMLKNLKKQLDDKERAEKAIIITQVTEKAKELCL 853
Query: 820 --KEYEFIGEIVE--GSMDDLREAVERLKK--PNRIVVLVSKEG-------YFAISVGD- 865
KE ++I ++ G+ L A++++K+ PN + S + A+ D
Sbjct: 854 ERKESKYIVSELKAFGNTKALDGALKQVKQFCPNSAAMFFSVDKDADKIYCLAAVPKSDV 913
Query: 866 NVNLNANDLAKKLTSIAGGGGGGRKDVAQGRIKDVSKAKEAIE 908
L A++ + + I GG GGG+ + AQ + + EAI+
Sbjct: 914 EKGLLASEWVQSVVDIIGGKGGGKAESAQASGNNPNSLNEAIQ 956
>sp|P35029|SYA_SULAC ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|1076156|pir||S53652 alanine--tRNA ligase (EC
6.1.1.7) - Sulfolobus acidocaldarius (fragment)
>gi|47504|emb|CAA41766.1| (X59038) alaS [Sulfolobus
solfataricus]
Length = 182
Score = 196 bits (494), Expect = 7e-49
Identities = 99/174 (56%), Positives = 114/174 (64%), Gaps = 4/174 (2%)
Query: 6 KTRMFEEEGWIRKKCKVCGKPFWTLDPDRETCGDPPCDEYQFIGKPGIPKKYTLDEMREK 65
+ F G+ RK C+ C PFWTLD +E C D PC +Y F T+ E REK
Sbjct: 10 RLNFFLSRGYERKICRSCSTPFWTLDKSKENCSDVPCTDYYFFDIKIKSPPLTVRESREK 69
Query: 66 FLKFFEKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPANPLVISQP 125
FL+FFEK H V PV+ +WRDD+ L ASI+DFQP+V SG A PPANPLV+SQP
Sbjct: 70 FLRFFEKRG---HTIVPPKPVVAKWRDDLYLTIASIVDFQPFVTSGLAKPPANPLVVSQP 126
Query: 126 SIRFTDIDNVGIT-GRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFEFFTKEL 178
IR D+DNVGIT GRH T FEM AHHAFNYP K IYW DETV A EFFT+EL
Sbjct: 127 CIRLEDVDNVGITFGRHLTTFEMAAHHAFNYPDKQIYWKDETVAFAKEFFTEEL 180
>gb|AAD50044.1|AC007980_9 (AC007980) 78688 [Arabidopsis thaliana]
Length = 955
Score = 196 bits (493), Expect = 1e-48
Identities = 243/992 (24%), Positives = 408/992 (40%), Gaps = 208/992 (20%)
Query: 62 MREKFLKFF--EKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPANP 119
+R+ ++ FF + H+ +P PV+P +L A + ++P + G ADP
Sbjct: 16 VRDTYVDFFRGKGHKFWPSS-----PVVPHNDPTLLFANAGMNQYKP-IFLGTADPNTEL 69
Query: 120 LVIS-----QPSIR----FTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELA 170
+S Q IR D+D+VG H T FEM+ + +F Y+ E +E A
Sbjct: 70 SKLSRACNTQKCIRAGGKHNDLDDVGKDTYHHTFFEMLGNWSFGD-----YFKKEAIEWA 124
Query: 171 FEFFTKE-------------------------------LKMKPEDITF----KENPWAGG 195
+E TK LK+ P K+N W G
Sbjct: 125 WELLTKVYGLPTDRIYATYFGGDEKAGLQPDNEARDIWLKVLPSGRVLPFGCKDNFWEMG 184
Query: 196 --GNAGPAFEVLYRG-----------------LEVATLVFMQYKKAPENAPEDQVVIIKG 236
G GP E+ Y LE+ LVF+Q+ + + + +
Sbjct: 185 DTGPCGPCTEIHYDRIGNRDAASLVNNDDPTCLEIWNLVFIQFNRESDGSLK-------- 236
Query: 237 DRYVPMETKVVDTGYGLERLVWMSQGTPTAYDA-VLGYVVEPLKRMAGVEKIDERILMEN 295
P+ K VDTG G ERL + Q + YD V + + +++ G ++ E+
Sbjct: 237 ----PLPAKHVDTGMGFERLTSVLQNKMSNYDTDVFMPIFDDIQKATGARPYSGKVGPED 292
Query: 296 SRLAGMFDIEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADG 355
V+ ++ A R +ADH + L+F +ADG
Sbjct: 293 -----------------------------VDRVDMAYR------VVADHIRTLSFAIADG 317
Query: 356 VIPSNVKAGYLARLLIRKSIRHLKEL--GLEVPLSEIVALHIKELHKTFPEFKEMEDVIL 413
P N Y+ R ++R+++R+ KE+ E + +V+ I+ + F E KE E I
Sbjct: 318 SRPGNEGREYVLRRILRRAVRYGKEILKAEEGFFNGLVSSVIRVMGDVFTELKEHEKKIT 377
Query: 414 EIIDLEEKKYSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAE 473
+II EE + +TL +G + R+ ++ +S + ++++G +L + +AE
Sbjct: 378 DIIKEEEASFCKTLAKGIEKFRKAGQAVQGNTLSG---DDAFILWDTYGFPLDLTQLMAE 434
Query: 474 KEGIKVHVPDNFYSIVAKEAEKEKEEKEEE-----VVDFELVKDLPETRTLYYEDPFM-- 526
+ G+ V V D F + + E+ + + ++ V+D + L + +D F
Sbjct: 435 ERGLLVDV-DGFNKAMEEARERSRSAQNKQAGGAIVMDADATSTLHKAGVSATDDSFKYI 493
Query: 527 ----KEFEARVLRVIGDWI-----------VLDQTAFYPEGGGQPYDTGVLFVNGSEVKV 571
E E + + ++ VL T+FY E GGQ +DTG++ + V
Sbjct: 494 WFQDHESELKAIYTGSTFLESSAASDNVGLVLGSTSFYAEQGGQIFDTGLIEGSFGTFNV 553
Query: 572 TNVQKVGKVIVH---KVENPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLG 628
NVQ G ++H + G G +V ++D++RR +HT TH+L AL VLG
Sbjct: 554 CNVQIFGGFVLHIGYLSKETGEVSVGDKVICKVDYERRKLIAPNHTCTHMLNYALKEVLG 613
Query: 629 KHVWQAGSQLTTDWARLDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQR 688
H+ Q GS + + R D SH K + E+LR IE + N+ + ++ V + +EA++
Sbjct: 614 DHIDQKGSIVLPEKLRFDFSHGKPVDPEDLRRIESIVNKQIKDELDVFSKEAVLSEAKRI 673
Query: 689 YGFRLYQGGVVPGRVIRVV----KIED---------WDV---QACGGTHLPSTGLVGPIK 732
G R G V P V RVV K+ED W + + CGGTH+ +T
Sbjct: 674 KGLRAVFGEVYPDPV-RVVSIGRKVEDLLADPENNEWSLLSSEFCGGTHITNTREAKAFA 732
Query: 733 ILRTERIQDGVERIIFACGEAAIKEWQK----EREI-----------------LKKASQV 771
+L E I G+ R+ E A ERE+ LK
Sbjct: 733 LLSEEGIAKGIRRVTAVTTECAFDALNAASLLEREVEDASRAEGSALEKKVSALKSRVDA 792
Query: 772 LRVPPEKLPETAERFF---NEWKEARKEV-EKLKKELAKLLVYELEAKVQKVKEYEFIGE 827
+P K + + NE ++A+K++ E+ K+ KL E+ K + I
Sbjct: 793 AIIPAAKKADIRTKIASLQNEVRKAQKKIAEQNLKKSVKLATEAAESAASDGKTFCIIQL 852
Query: 828 IVEGSMDDLREAVERL--KKPNRIVVLVSKEGYFAISVGDNVNLNAN-----DLAKKLTS 880
V +REAV ++ KK I+V + E V V ++ D+ + LT+
Sbjct: 853 DVGLDAAAVREAVSKVMEKKGMSIMVFSTDESTNKAVVCAGVPEKSDQFKPLDVTEWLTT 912
Query: 881 ----IAGGGGGGRKDVAQGRIKDVSKAKEAIE 908
+ G G G+ +A G+ D S+ + A++
Sbjct: 913 ALGPLKGRCGKGKGGLASGQGTDASQVQAALD 944
>gb|AAF05592.1|AF188717_1 (AF188717) alanyl-tRNA synthetase [Dictyostelium discoideum]
Length = 946
Score = 194 bits (488), Expect = 4e-48
Identities = 240/996 (24%), Positives = 410/996 (41%), Gaps = 209/996 (20%)
Query: 59 LDEMREKFLKFFEKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPAN 118
++++R+ F+ FF E Y H V V+P +L A + F+P + G+ +P +
Sbjct: 3 VNQIRKTFIDFFR--EKYEHTFVPSSAVIPHDDPTLLFANAGMNQFKP-IFLGQVNPKSE 59
Query: 119 PL-----VISQPSIR----FTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVEL 169
V SQ IR D+D+VG H T FEM+ + +F Y+ E +
Sbjct: 60 QAKLKRAVNSQKCIRAGGKHNDLDDVGKDTYHHTFFEMLGNWSFGN-----YFKKEAITW 114
Query: 170 AFEFFTKELKMKPEDIT-----------------------------------FKENPWAG 194
A+E T+ K+ E + KEN W
Sbjct: 115 AWELLTEVYKLDKERLYVTYFRGDPEKGLEADLEAKNLWLQYLPEERVLPFGMKENFWEM 174
Query: 195 G--GNAGPAFEVLYRG-----------------LEVATLVFMQYKKAPENAPEDQVVIIK 235
G G GP E+ Y +E+ LVF+QY + + +
Sbjct: 175 GDQGPCGPCSEIHYDKVEGRDGASFVNADDPTLIEIWNLVFIQYNREADKSLR------- 227
Query: 236 GDRYVPMETKVVDTGYGLERLVWMSQGTPTAYDA-VLGYVVEPLKRMAGVEKIDERILME 294
P+ K VDTG GLERL + Q PT YD V + ++ + G +
Sbjct: 228 -----PLPQKHVDTGMGLERLTSIIQKVPTNYDTDVFMPIFAAIQEVTGYPE-------- 274
Query: 295 NSRLAGMFDIEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLAD 354
G ED ++++ A R IADH + LTF +AD
Sbjct: 275 --PYGGKVGAED------------------TQQVDMAYR------VIADHIRTLTFSIAD 308
Query: 355 GVIPSNVKAGYLARLLIRKSIRHLKELGLEVP---LSEIVALHIKELHKTFPEFKEMEDV 411
G PS G + R ++R+++R+ K+ L P S++V + I + FPE ++ +
Sbjct: 309 GAAPSVDGRGQVLRRILRRAVRYGKQK-LNAPTGFFSKLVDVVIANFGEFFPELRKKPEH 367
Query: 412 ILEIIDLEEKKYSETLKRGSDLVRREIAKLKKKGMSE-IPLEKLITFYESHGLTPELVKE 470
I ++ EE +++TL++G E K+ KK ++ + E +G +L
Sbjct: 368 IKMVLTREEDMFNKTLEKGIV----EFEKMIKKSVNNTLSAENAYFLSTCYGFPIDLTTI 423
Query: 471 IAEKEGIKVHVPDNFYSIVAKEAEKEKEEKEEEVVDFELVKD----LPETRTLYYEDPFM 526
+AE++ KV + + + ++E +++ ++E+ V+ L + L +D F
Sbjct: 424 MAEEKNYKVDIK-GYEGLCEAQSEIDRKRQKEKKVELTLGAEANAWLKNNDIKPTDDSFK 482
Query: 527 -KEFEAR-VLRVIGDW--------------IVLDQTAFYPEGGGQPYDTGVL-FVNGSEV 569
K+ E + V++ I + +VL+ + FY E GGQ YD G L F++ +
Sbjct: 483 YKQHEIQSVIKAIWNGKEFVDTAPKGTLIGVVLENSNFYAEQGGQIYDIGQLSFIDDQKT 542
Query: 570 K--VTNVQKVGKVIVH----KVENPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGAL 623
V + + G ++H E L K G V +D+ RR M +HT TH++ AL
Sbjct: 543 AFDVKDCKVFGGYVLHIGYLSYECDSL-KVGDRVELTVDYTRRSPIMSNHTSTHMVNYAL 601
Query: 624 VRVLGKHVWQAGSQLTTDWARLDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRT 683
+LG + Q GS + R D S + I+ +EL +I+++ N + + V + +
Sbjct: 602 KNILGDGIDQRGSFVDAQRFRFDFSFGRAITKDELIKIDQIVNDQIFKQLDVHAKEVGLA 661
Query: 684 EAEQRYGFRLYQGGVVPGRVIRVVKI----------------EDWDVQACGGTHLPSTGL 727
A++ G R G V P V RVV + ++ ++ CGGTHL +T
Sbjct: 662 SAKKINGLRAVFGEVYPDPV-RVVSVGVPVEQLIENPTNPEWANYSIEFCGGTHLSNTKQ 720
Query: 728 VGPIKILRTERIQDGVERIIFACGEAAIKEWQKEREILKKASQVLRVPPEKLPETAERFF 787
I E + GV RI+ G A + +E+ + + L++ +L +
Sbjct: 721 AELFTITSEETLGAGVRRIVAVTGSEAASAIELNKELEVRFNNALKLSGSELAKEIVSLL 780
Query: 788 NEWK-------------EARKEVEKLK----KELAKLLVYELEAKVQKVKEY------EF 824
+ K E KEV+ L+ KE +L + + ++K E +
Sbjct: 781 DLLKVVTISASVRMNLVETLKEVQALQRKQVKEQETILAQQAQTYLEKTSEELAKSQPKV 840
Query: 825 IGEIVEGSMDD--LREAVERL--KKPNRIVVLVSKE---------GYFAISVGDNVNLNA 871
++V + + + E ++++ K P ++L+S + G + L A
Sbjct: 841 FVDLVNFNSNTPLITETIKKIQTKSPMTAIMLISPDEEKGKVTCIGIVPKDSEISKTLTA 900
Query: 872 NDLAKKLTSIAGGGGGGRKDVAQGRIKDVSKAKEAI 907
N K+T + GG GGG+ DVAQG + K EAI
Sbjct: 901 NAWVVKVTEVLGGKGGGKVDVAQGVGSKLDKIDEAI 936
>pir||S32671 alanine--tRNA ligase (EC 6.1.1.7) - Arabidopsis thaliana
(fragment)
Length = 989
Score = 193 bits (485), Expect = 8e-48
Identities = 241/992 (24%), Positives = 407/992 (40%), Gaps = 208/992 (20%)
Query: 62 MREKFLKFF--EKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPANP 119
+R+ ++ FF + H+ +P PV+P +L A + ++P + G ADP
Sbjct: 50 VRDTYVDFFRGKGHKFWPSS-----PVVPHNDPTLLFANAGMNQYKP-IFLGTADPNTEL 103
Query: 120 LVIS-----QPSIR----FTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELA 170
+S Q IR D+D+VG H T FEM+ + +F Y+ E +E A
Sbjct: 104 SKLSRACNTQKCIRAGGKHNDLDDVGKDTYHHTFFEMLGNWSFGD-----YFKKEAIEWA 158
Query: 171 FEFFTKE-------------------------------LKMKPEDITF----KENPWAGG 195
+E TK LK+ P K+N W G
Sbjct: 159 WELLTKVYGLPTDRIYATYFGRDEKAGLQPDNEARDIWLKVLPSGRVLPFGCKDNFWEMG 218
Query: 196 --GNAGPAFEVLYRG-----------------LEVATLVFMQYKKAPENAPEDQVVIIKG 236
G GP E+ Y LE+ LVF+Q+ + + + +
Sbjct: 219 DTGPCGPCTEIHYDRIGNRDAASLVNNDDPTCLEIWNLVFIQFNRESDGSLK-------- 270
Query: 237 DRYVPMETKVVDTGYGLERLVWMSQGTPTAYDA-VLGYVVEPLKRMAGVEKIDERILMEN 295
P+ K VDTG G ERL + Q + YD V + + +++ G ++ E+
Sbjct: 271 ----PLPAKHVDTGMGFERLTSVLQNKMSNYDTDVFMPIFDDIQKATGARPYSGKVGPED 326
Query: 296 SRLAGMFDIEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADG 355
V+ ++ A R +ADH + L+F +ADG
Sbjct: 327 -----------------------------VDRVDMAYR------VVADHIRTLSFAIADG 351
Query: 356 VIPSNVKAGYLARLLIRKSIRHLKEL--GLEVPLSEIVALHIKELHKTFPEFKEMEDVIL 413
P N Y+ R ++R+++R+ KE+ E + +V+ I+ + F E KE E I
Sbjct: 352 SRPGNEGREYVLRRILRRAVRYGKEILKAEEGFFNGLVSSVIRVMGDVFTELKEHEKKIT 411
Query: 414 EIIDLEEKKYSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAE 473
+II EE + +TL +G + R+ ++ +S + ++++G +L + +AE
Sbjct: 412 DIIKEEEASFCKTLAKGIEKFRKAGQAVQGNTLSG---DDAFILWDTYGFPLDLTQLMAE 468
Query: 474 KEGIKVHVPDNFYSIVAKEAEKEKEEKEEE-----VVDFELVKDLPETRTLYYEDPFM-- 526
+ G+ V V D F + + E+ + + ++ V+D + L + +D F
Sbjct: 469 ERGLLVDV-DGFNKAMEEARERSRSAQNKQAGGAIVMDADATSTLHKAGVSATDDSFKYI 527
Query: 527 ----KEFEARVLRVIGDWI-----------VLDQTAFYPEGGGQPYDTGVLFVNGSEVKV 571
E E + + ++ VL T+FY E GGQ +DTG++ + V
Sbjct: 528 WFQDHESELKAIYTGSTFLESSAASDNVGLVLGSTSFYAEQGGQIFDTGLIEGSFGTFNV 587
Query: 572 TNVQKVGKVIVH---KVENPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLG 628
NVQ G ++H + G G +V ++D++RR +HT TH+L AL VLG
Sbjct: 588 CNVQIFGGFVLHIGYLSKETGEVSVGDKVICKVDYERRKLIAPNHTCTHMLNYALKEVLG 647
Query: 629 KHVWQAGSQLTTDWARLDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQR 688
H+ Q GS + + R D SH K + E+LR IE + N+ + ++ V + +EA++
Sbjct: 648 DHIDQKGSIVLPEKLRFDFSHGKPVDPEDLRRIESIVNKQIKDELDVFSKEAVLSEAKRI 707
Query: 689 YGFRLYQGGVVPGRVIRVV----KIED---------WDV---QACGGTHLPSTGLVGPIK 732
G R G P V RVV K+ED W + + CGGTH+ +T
Sbjct: 708 KGLRAVFGEAYPDPV-RVVSIGRKVEDLLADPENNEWSLLSSEFCGGTHITNTREAKAFA 766
Query: 733 ILRTERIQDGVERIIFACGEAAIKEWQK----EREI-----------------LKKASQV 771
+L E I G+ R+ E A ERE+ LK
Sbjct: 767 LLSEEGIAKGIRRVTAVTTECAFDALNAASLLEREVEDASRAEGSALEKKVSALKSRVDA 826
Query: 772 LRVPPEKLPETAERFF---NEWKEARKEV-EKLKKELAKLLVYELEAKVQKVKEYEFIGE 827
+P K + + NE ++A+K++ E+ K+ KL E+ K + I
Sbjct: 827 AIIPAAKKADIRTKIASLQNEVRKAQKKIAEQNLKKSVKLATEAAESAASDGKTFCIIQL 886
Query: 828 IVEGSMDDLREAVERL--KKPNRIVVLVSKEGYFAISVGDNVNLNAN-----DLAKKLTS 880
V ++EAV ++ KK I+V + E V V ++ D+ + LT+
Sbjct: 887 DVGLDAAAVQEAVSKVMEKKGMSIMVFSTDESTNKAVVCAGVPEKSDQFKPLDVTEWLTT 946
Query: 881 ----IAGGGGGGRKDVAQGRIKDVSKAKEAIE 908
+ G G G+ +A G+ D S+ + A++
Sbjct: 947 ALGPLKGRCGKGKGGLASGQGTDASQVQAALD 978
>sp|P36428|SYA_ARATH ALANYL-TRNA SYNTHETASE, MITOCHONDRIAL PRECURSOR (ALANINE--TRNA
LIGASE) (ALARS) >gi|1673365|emb|CAA80380.1| (Z22673)
mitochondrial tRNA-Ala synthetase [Arabidopsis thaliana]
Length = 1003
Score = 193 bits (485), Expect = 8e-48
Identities = 241/992 (24%), Positives = 407/992 (40%), Gaps = 208/992 (20%)
Query: 62 MREKFLKFF--EKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPANP 119
+R+ ++ FF + H+ +P PV+P +L A + ++P + G ADP
Sbjct: 64 VRDTYVDFFRGKGHKFWPSS-----PVVPHNDPTLLFANAGMNQYKP-IFLGTADPNTEL 117
Query: 120 LVIS-----QPSIR----FTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELA 170
+S Q IR D+D+VG H T FEM+ + +F Y+ E +E A
Sbjct: 118 SKLSRACNTQKCIRAGGKHNDLDDVGKDTYHHTFFEMLGNWSFGD-----YFKKEAIEWA 172
Query: 171 FEFFTKE-------------------------------LKMKPEDITF----KENPWAGG 195
+E TK LK+ P K+N W G
Sbjct: 173 WELLTKVYGLPTDRIYATYFGRDEKAGLQPDNEARDIWLKVLPSGRVLPFGCKDNFWEMG 232
Query: 196 --GNAGPAFEVLYRG-----------------LEVATLVFMQYKKAPENAPEDQVVIIKG 236
G GP E+ Y LE+ LVF+Q+ + + + +
Sbjct: 233 DTGPCGPCTEIHYDRIGNRDAASLVNNDDPTCLEIWNLVFIQFNRESDGSLK-------- 284
Query: 237 DRYVPMETKVVDTGYGLERLVWMSQGTPTAYDA-VLGYVVEPLKRMAGVEKIDERILMEN 295
P+ K VDTG G ERL + Q + YD V + + +++ G ++ E+
Sbjct: 285 ----PLPAKHVDTGMGFERLTSVLQNKMSNYDTDVFMPIFDDIQKATGARPYSGKVGPED 340
Query: 296 SRLAGMFDIEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADG 355
V+ ++ A R +ADH + L+F +ADG
Sbjct: 341 -----------------------------VDRVDMAYR------VVADHIRTLSFAIADG 365
Query: 356 VIPSNVKAGYLARLLIRKSIRHLKEL--GLEVPLSEIVALHIKELHKTFPEFKEMEDVIL 413
P N Y+ R ++R+++R+ KE+ E + +V+ I+ + F E KE E I
Sbjct: 366 SRPGNEGREYVLRRILRRAVRYGKEILKAEEGFFNGLVSSVIRVMGDVFTELKEHEKKIT 425
Query: 414 EIIDLEEKKYSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAE 473
+II EE + +TL +G + R+ ++ +S + ++++G +L + +AE
Sbjct: 426 DIIKEEEASFCKTLAKGIEKFRKAGQAVQGNTLSG---DDAFILWDTYGFPLDLTQLMAE 482
Query: 474 KEGIKVHVPDNFYSIVAKEAEKEKEEKEEE-----VVDFELVKDLPETRTLYYEDPFM-- 526
+ G+ V V D F + + E+ + + ++ V+D + L + +D F
Sbjct: 483 ERGLLVDV-DGFNKAMEEARERSRSAQNKQAGGAIVMDADATSTLHKAGVSATDDSFKYI 541
Query: 527 ----KEFEARVLRVIGDWI-----------VLDQTAFYPEGGGQPYDTGVLFVNGSEVKV 571
E E + + ++ VL T+FY E GGQ +DTG++ + V
Sbjct: 542 WFQDHESELKAIYTGSTFLESSAASDNVGLVLGSTSFYAEQGGQIFDTGLIEGSFGTFNV 601
Query: 572 TNVQKVGKVIVH---KVENPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLG 628
NVQ G ++H + G G +V ++D++RR +HT TH+L AL VLG
Sbjct: 602 CNVQIFGGFVLHIGYLSKETGEVSVGDKVICKVDYERRKLIAPNHTCTHMLNYALKEVLG 661
Query: 629 KHVWQAGSQLTTDWARLDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQR 688
H+ Q GS + + R D SH K + E+LR IE + N+ + ++ V + +EA++
Sbjct: 662 DHIDQKGSIVLPEKLRFDFSHGKPVDPEDLRRIESIVNKQIKDELDVFSKEAVLSEAKRI 721
Query: 689 YGFRLYQGGVVPGRVIRVV----KIED---------WDV---QACGGTHLPSTGLVGPIK 732
G R G P V RVV K+ED W + + CGGTH+ +T
Sbjct: 722 KGLRAVFGEAYPDPV-RVVSIGRKVEDLLADPENNEWSLLSSEFCGGTHITNTREAKAFA 780
Query: 733 ILRTERIQDGVERIIFACGEAAIKEWQK----EREI-----------------LKKASQV 771
+L E I G+ R+ E A ERE+ LK
Sbjct: 781 LLSEEGIAKGIRRVTAVTTECAFDALNAASLLEREVEDASRAEGSALEKKVSALKSRVDA 840
Query: 772 LRVPPEKLPETAERFF---NEWKEARKEV-EKLKKELAKLLVYELEAKVQKVKEYEFIGE 827
+P K + + NE ++A+K++ E+ K+ KL E+ K + I
Sbjct: 841 AIIPAAKKADIRTKIASLQNEVRKAQKKIAEQNLKKSVKLATEAAESAASDGKTFCIIQL 900
Query: 828 IVEGSMDDLREAVERL--KKPNRIVVLVSKEGYFAISVGDNVNLNAN-----DLAKKLTS 880
V ++EAV ++ KK I+V + E V V ++ D+ + LT+
Sbjct: 901 DVGLDAAAVQEAVSKVMEKKGMSIMVFSTDESTNKAVVCAGVPEKSDQFKPLDVTEWLTT 960
Query: 881 ----IAGGGGGGRKDVAQGRIKDVSKAKEAIE 908
+ G G G+ +A G+ D S+ + A++
Sbjct: 961 ALGPLKGRCGKGKGGLASGQGTDASQVQAALD 992
>emb|CAA80381.1| (Z22673) cytosolic tRNA-Ala synthetase [Arabidopsis thaliana]
Length = 955
Score = 193 bits (485), Expect = 8e-48
Identities = 241/992 (24%), Positives = 407/992 (40%), Gaps = 208/992 (20%)
Query: 62 MREKFLKFF--EKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPANP 119
+R+ ++ FF + H+ +P PV+P +L A + ++P + G ADP
Sbjct: 16 VRDTYVDFFRGKGHKFWPSS-----PVVPHNDPTLLFANAGMNQYKP-IFLGTADPNTEL 69
Query: 120 LVIS-----QPSIR----FTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELA 170
+S Q IR D+D+VG H T FEM+ + +F Y+ E +E A
Sbjct: 70 SKLSRACNTQKCIRAGGKHNDLDDVGKDTYHHTFFEMLGNWSFGD-----YFKKEAIEWA 124
Query: 171 FEFFTKE-------------------------------LKMKPEDITF----KENPWAGG 195
+E TK LK+ P K+N W G
Sbjct: 125 WELLTKVYGLPTDRIYATYFGRDEKAGLQPDNEARDIWLKVLPSGRVLPFGCKDNFWEMG 184
Query: 196 --GNAGPAFEVLYRG-----------------LEVATLVFMQYKKAPENAPEDQVVIIKG 236
G GP E+ Y LE+ LVF+Q+ + + + +
Sbjct: 185 DTGPCGPCTEIHYDRIGNRDAASLVNNDDPTCLEIWNLVFIQFNRESDGSLK-------- 236
Query: 237 DRYVPMETKVVDTGYGLERLVWMSQGTPTAYDA-VLGYVVEPLKRMAGVEKIDERILMEN 295
P+ K VDTG G ERL + Q + YD V + + +++ G ++ E+
Sbjct: 237 ----PLPAKHVDTGMGFERLTSVLQNKMSNYDTDVFMPIFDDIQKATGARPYSGKVGPED 292
Query: 296 SRLAGMFDIEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADG 355
V+ ++ A R +ADH + L+F +ADG
Sbjct: 293 -----------------------------VDRVDMAYR------VVADHIRTLSFAIADG 317
Query: 356 VIPSNVKAGYLARLLIRKSIRHLKEL--GLEVPLSEIVALHIKELHKTFPEFKEMEDVIL 413
P N Y+ R ++R+++R+ KE+ E + +V+ I+ + F E KE E I
Sbjct: 318 SRPGNEGREYVLRRILRRAVRYGKEILKAEEGFFNGLVSSVIRVMGDVFTELKEHEKKIT 377
Query: 414 EIIDLEEKKYSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAE 473
+II EE + +TL +G + R+ ++ +S + ++++G +L + +AE
Sbjct: 378 DIIKEEEASFCKTLAKGIEKFRKAGQAVQGNTLSG---DDAFILWDTYGFPLDLTQLMAE 434
Query: 474 KEGIKVHVPDNFYSIVAKEAEKEKEEKEEE-----VVDFELVKDLPETRTLYYEDPFM-- 526
+ G+ V V D F + + E+ + + ++ V+D + L + +D F
Sbjct: 435 ERGLLVDV-DGFNKAMEEARERSRSAQNKQAGGAIVMDADATSTLHKAGVSATDDSFKYI 493
Query: 527 ----KEFEARVLRVIGDWI-----------VLDQTAFYPEGGGQPYDTGVLFVNGSEVKV 571
E E + + ++ VL T+FY E GGQ +DTG++ + V
Sbjct: 494 WFQDHESELKAIYTGSTFLESSAASDNVGLVLGSTSFYAEQGGQIFDTGLIEGSFGTFNV 553
Query: 572 TNVQKVGKVIVH---KVENPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLG 628
NVQ G ++H + G G +V ++D++RR +HT TH+L AL VLG
Sbjct: 554 CNVQIFGGFVLHIGYLSKETGEVSVGDKVICKVDYERRKLIAPNHTCTHMLNYALKEVLG 613
Query: 629 KHVWQAGSQLTTDWARLDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQR 688
H+ Q GS + + R D SH K + E+LR IE + N+ + ++ V + +EA++
Sbjct: 614 DHIDQKGSIVLPEKLRFDFSHGKPVDPEDLRRIESIVNKQIKDELDVFSKEAVLSEAKRI 673
Query: 689 YGFRLYQGGVVPGRVIRVV----KIED---------WDV---QACGGTHLPSTGLVGPIK 732
G R G P V RVV K+ED W + + CGGTH+ +T
Sbjct: 674 KGLRAVFGEAYPDPV-RVVSIGRKVEDLLADPENNEWSLLSSEFCGGTHITNTREAKAFA 732
Query: 733 ILRTERIQDGVERIIFACGEAAIKEWQK----EREI-----------------LKKASQV 771
+L E I G+ R+ E A ERE+ LK
Sbjct: 733 LLSEEGIAKGIRRVTAVTTECAFDALNAASLLEREVEDASRAEGSALEKKVSALKSRVDA 792
Query: 772 LRVPPEKLPETAERFF---NEWKEARKEV-EKLKKELAKLLVYELEAKVQKVKEYEFIGE 827
+P K + + NE ++A+K++ E+ K+ KL E+ K + I
Sbjct: 793 AIIPAAKKADIRTKIASLQNEVRKAQKKIAEQNLKKSVKLATEAAESAASDGKTFCIIQL 852
Query: 828 IVEGSMDDLREAVERL--KKPNRIVVLVSKEGYFAISVGDNVNLNAN-----DLAKKLTS 880
V ++EAV ++ KK I+V + E V V ++ D+ + LT+
Sbjct: 853 DVGLDAAAVQEAVSKVMEKKGMSIMVFSTDESTNKAVVCAGVPEKSDQFKPLDVTEWLTT 912
Query: 881 ----IAGGGGGGRKDVAQGRIKDVSKAKEAIE 908
+ G G G+ +A G+ D S+ + A++
Sbjct: 913 ALGPLKGRCGKGKGGLASGQGTDASQVQAALD 944
>gb|AAF52657.1| (AE003621) Aats-ala gene product [Drosophila melanogaster]
Length = 966
Score = 190 bits (479), Expect = 4e-47
Identities = 245/1020 (24%), Positives = 404/1020 (39%), Gaps = 232/1020 (22%)
Query: 55 KKYTLDEMREKFLKFF-EKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEA 113
K T E+R +L FF E+ +Y H +P +L A + F+P + G A
Sbjct: 2 KLLTAKEVRNAYLDFFKEQKHIYVHSS----STIPLDDPTLLFANAGMNQFKP-IFLGTA 56
Query: 114 DPP---------ANPLVISQPSIRFTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWID 164
DP AN + + D+D+VG H T FEM+ + +F Y+
Sbjct: 57 DPNSEMSKWVRVANTQKCIRAGGKHNDLDDVGKDVYHHTFFEMLGNWSFGD-----YFKK 111
Query: 165 ETVELAFEFFTK---------------------------------ELKMKPEDI---TFK 188
E A+EF T+ +L +KPE I + K
Sbjct: 112 EICSWAWEFLTQRLALPKDRLYVTYFGGDAASGLEPDLECKQMWLDLGLKPEHILPGSMK 171
Query: 189 ENPWAGG--GNAGPAFEVLYRG-----------------LEVATLVFMQYKKAPENAPED 229
+N W G G GP E+ + LE+ LVF+QY + + + +
Sbjct: 172 DNFWEMGETGPCGPCSELHFDRIGGRSVPELVNMDDPDVLEIWNLVFIQYNRESDGSLKQ 231
Query: 230 QVVIIKGDRYVPMETKVVDTGYGLERLVWMSQGTPTAYDAVLGY-VVEPLKRMAGVEKID 288
+ K +D G G ERLV + Q + YD L + + ++ G
Sbjct: 232 ------------LPKKHIDCGMGFERLVSVIQNKRSNYDTDLFVPLFDAIQAGTGAPPYQ 279
Query: 289 ERILMENSRLAGMFDIEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKAL 348
R+ ++ V+ ++ A R +ADH + +
Sbjct: 280 GRVGADD-----------------------------VDGIDMAYR------VLADHARTI 304
Query: 349 TFMLADGVIPSNVKAGYLARLLIRKSIRHLKELGLEVP--LSEIVALHIKELHKTFPEFK 406
T LADG P N GY+ R ++R+++R+ E P + +V + L FPE K
Sbjct: 305 TIALADGGTPDNTGRGYVLRRILRRAVRYATEKLNAKPGFFATLVNTVVDLLGDAFPEVK 364
Query: 407 EMEDVILEIIDLEEKKYSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPE 466
+ I++II+ EE ++ +TL RG +L+ R I KL + + IP + Y+++G +
Sbjct: 365 KDPQHIIDIINEEELQFLKTLTRGRNLLNRTIEKLGNQ--TTIPGDVAWRLYDTYGFPVD 422
Query: 467 LVKEIAEKEGIKVHVPDNF----YSIVAKEAEKEKEEKEEEVVDFELVKDLPETRTLYYE 522
L + +AE++ +K+ + D + ++ K + EE +D + L E
Sbjct: 423 LTQLMAEEKSLKIDM-DGYEAAKHNSYVLSQGKGASKIEEINLDVHAISQLQEQGVPPTN 481
Query: 523 DPFMKEFEAR------------------VLRVIGDW-----------IVLDQTAFYPEGG 553
D F ++EA LR + IVLD+T FY E G
Sbjct: 482 DTFKYKYEAVSDERDSAYNYGVCNSKIVALRFENQFVNEITSGQKAGIVLDKTNFYAESG 541
Query: 554 GQPYDTGVLF-VN--GSEVKVTNVQKVGKVIVHKVENPGLFKEGMEVRGRIDWDRRIQHM 610
GQ YD G L VN +E V V G I+H G K G E+ ID +RR M
Sbjct: 542 GQIYDQGALVKVNDEANEFLVDRVYNRGGYILHIGVVEGTLKVGDELELHIDVERRWLTM 601
Query: 611 RHHTGTHVLMGALVRVLGKHVWQAGSQLTTDWARLDISHYKRISDEELREIERLANRIVM 670
++H+ TH L L++VLGK Q GS + + R D + ++ E++ + E+L +V
Sbjct: 602 KNHSATHALNHCLLQVLGKDTEQKGSLVVPEKLRFDFNSKAAMTIEQVSKTEQLTKEMVY 661
Query: 671 EDRKVTWEWLPRTEAEQRYGFRLYQGGVVPGRVIRVVKI----------------EDWDV 714
++ + + A++ G R V P V RV+ E V
Sbjct: 662 KNVPIYAKESKLALAKKIRGLRSVFDEVYPDPV-RVISFGVPVDELEQNPDSEAGEQTSV 720
Query: 715 QACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGEAAIKEWQK----EREILK---- 766
+ CGGTHL +G + I E I G+ RI+ G A+K +K E+EI++
Sbjct: 721 EFCGGTHLRRSGHIMDFVISSEEAIAKGIRRIVALTGPEALKALKKSEAFEQEIVRLKAT 780
Query: 767 ----KASQVLRVPPEKLPETAERF------FNEWKEARKEVEKLKKEL------------ 804
K+ + + +++ E E+ + + E R ++ LKK L
Sbjct: 781 IDNDKSGKDSKSHVKEIVELTEQISHATIPYVKKDEMRNLLKGLKKTLDDKERALRAAVS 840
Query: 805 ----------------AKLLVYELEAKVQKVKEYEFIGEIVEGSMDDLREAVERLKKPNR 848
A +LV +LEA K + + V + D + ++
Sbjct: 841 VTVVERAKTLCEANPNATVLVEQLEA-FNNTKALDAALKQVRSQLPDAAAMFLSVDADSK 899
Query: 849 IVVLVSKEGYFAISVGDNVNLNANDLAKKLTSIAGGGGGGRKDVAQGRIKDVSKAKEAIE 908
+ +S A+ G L AN+ + +++ GG GGG+ + AQ + K E ++
Sbjct: 900 KIFCLSSVPKSAVEKG----LKANEWVQHVSATLGGKGGGKPESAQASGTNYEKVDEIVQ 955
>pir||T29466 hypothetical protein F28H1.3 - Caenorhabditis elegans
>gi|1938531|gb|AAB52339.1| (U97013) Similar to
aminoacyl-tRNA synthetase; coded for by C. elegans cDNA
yk126g5.3; coded for by C. elegans cDNA yk178b12.5;
coded for by C. elegans cDNA yk120a6.5; coded for by C.
elegans cDNA yk69h7.5; coded for by C. elegans cDNA
yk126g5.5; coded>
Length = 968
Score = 189 bits (476), Expect = 1e-46
Identities = 248/1015 (24%), Positives = 407/1015 (39%), Gaps = 220/1015 (21%)
Query: 55 KKYTLDEMREKFLKFF-EKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEA 113
K T E+R F+ FF EK E H V V+P +L A + F+P + G A
Sbjct: 2 KHLTASEVRSTFINFFREKKE---HTYVHSSSVIPHDDPTLLFANAGMNQFKPLFL-GIA 57
Query: 114 DPPAN-----PLVISQPSIR----FTDIDNVGITGRHFTIFEMMAHHAFN--YPGKPIYW 162
DP ++ V +Q IR D+D+VG H T FEM+ + +F + + I W
Sbjct: 58 DPNSDLAKLKRAVNTQKCIRAGGKHNDLDDVGKDVYHHTYFEMLGNWSFGDYFKKEIITW 117
Query: 163 IDETVELAFEFFTKELKMK----------PED-------------------ITFKENPWA 193
E + + + L + P D K+N W
Sbjct: 118 AWELLTTVYGIPAERLYVSVFGGDEANGVPADSEARDIWRSVGVPDERILNFGMKDNFWE 177
Query: 194 GG--GNAGPAFEVLYRGL-----------------EVATLVFMQYKKAPENAPEDQVVII 234
G G GP E+ Y + E+ LVF+Q+ +
Sbjct: 178 MGDVGPCGPCSEIHYDRIGNRDASHLVNADDPMVVEIWNLVFIQFNRE------------ 225
Query: 235 KGDRYVPMETKVVDTGYGLERLVWMSQGTPTAYDA-VLGYVVEPLKRMAGVEKIDERILM 293
+G P+ K +D G GLERL+ + Q + YD + + E + + +GV
Sbjct: 226 EGGVLKPLPAKHIDCGLGLERLIAVMQDKTSNYDTDIFQPIFEAIHKGSGVRAY------ 279
Query: 294 ENSRLAGMFDIEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLA 353
G ED + + + +ADH + LT L+
Sbjct: 280 -----TGFIGDEDKDGVDMAYR------------------------VVADHVRTLTIALS 310
Query: 354 DGVIPSNVKAGYLARLLIRKSIRHLKELGLEVP--LSEIVALHIKELHKTFPEFKEMEDV 411
DG P N GY+ R ++R+ +R+ E P + +V + I L +TFPE
Sbjct: 311 DGGRPDNSGRGYVLRRILRRGVRYASEKLNAQPGFFASLVPVVISILGETFPELSRDPVT 370
Query: 412 ILEIIDLEEKKYSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEI 471
+++II+ EEK++ +TL RG L +R + L + G P + Y+++G +L + +
Sbjct: 371 VMDIINDEEKQFLKTLSRGRVLFQRAVQSLPE-GTMTFPGDVSWRLYDTYGFPADLTQLM 429
Query: 472 AEKEGIKVHVPDNFYSIVAKEAEKEKEE----KEEEVVDFEL-------VKDLPETR-TL 519
AE++G+ V DN A+ E K + +D ++ K +P T +
Sbjct: 430 AEEKGLSV---DNTAFEEARRKAIETSSAGTGKFRDTLDLDVHALAELQQKGVPTTDDSP 486
Query: 520 YYEDPFMKE-------FEARVLRVIG----------------DWIVLDQTAFYPEGGGQP 556
Y F E FE V +++ I+LD+T FY E GGQ
Sbjct: 487 KYAYTFTGEGSDAVYKFEPCVGKILAIRRDGKFVDQLAAGEEGAILLDRTNFYAEQGGQI 546
Query: 557 YDTGVLF-VN--GSEVKVTNVQKVGKVIVHKVENPGLFKEGMEVRGRIDWDRRIQHMRHH 613
YD GVL VN +E V+N Q G IV G F G +V R D DR+ M++H
Sbjct: 547 YDVGVLTKVNDESNEFNVSNCQVRGGYIVLVGSAEGSFSVGDQVNERFDEDRKQLIMKNH 606
Query: 614 TGTHVLMGALVRVLGKHVWQAGSQLTTDWARLDISHYKRISDEELREIERLANRIVMEDR 673
TGTHVL AL +VL Q GS + D R D ++ ++ +++++ E A +++
Sbjct: 607 TGTHVLNYALRKVLADSD-QKGSLVAPDRMRFDFTNKAGMTVQQVKKAEEYAQQLIDTKG 665
Query: 674 KVTWEWLPRTEAEQRYGFRLYQGGVVPGRVIRVVKI----------------EDWDVQAC 717
+V + P EA++ G R P V RVV + ++ V+ C
Sbjct: 666 QVYAKNSPLGEAKKVKGLRAMFDETYPDPV-RVVAVGTPVEQLLQNPDAEEGQNTTVEFC 724
Query: 718 GGTHLPSTGLVGPIKILRTERIQDGVERIIFACGEAAIKEWQKEREILKKASQVLRVPPE 777
GGTHL + +G I I E I G+ RI+ G A + + + + + + +
Sbjct: 725 GGTHLQNVSHIGRIVIASEEAIAKGIRRIVALTGPEAERAIARADRLTARLEEESKHADK 784
Query: 778 KLPETAERFFNEWKEARKEVEKLKKEL--AKLLVYELEAKVQKVK------------EYE 823
K A + +++K +K+++++ E A+L + ++ +K K +
Sbjct: 785 KDELLANK--DKFKALQKKIQEIVDEANGAQLPYWRKDSIREKAKAIQKTLDGYTKAQQA 842
Query: 824 FIGEIVEGSMDDLREAVER--------------LKKPNRIVVLVSKEGYFAISVGDNV-- 867
+ E V G +L E+ N + +L + A SV ++
Sbjct: 843 AVAEKVLGEAKELAAVAEQPTVLVHVFAANANSKAIDNALKLLKDTKAVMAFSVNEDSGK 902
Query: 868 --------------NLNANDLAKKLTSIAGGGGGGRKDVAQGRIKDVSKAKEAIE 908
L AN+ ++ ++ GG GGG+ AQ ++V K A+E
Sbjct: 903 VLCLAKVDKSLVSNGLKANEWVNEVCTVLGGKGGGKDANAQLTGENVDKLDAAVE 957
>gi|4501841 alanyl-tRNA synthetase [Homo sapiens]
>gi|1351144|sp|P49588|SYA_HUMAN ALANYL-TRNA SYNTHETASE
(ALANINE--TRNA LIGASE) (ALARS) >gi|7437613|pir||I60107
alanine--tRNA ligase (EC 6.1.1.7) - human
>gi|1015321|dbj|BAA06808.1| (D32050) alanyl-tRNA
synthetase [Homo sapiens]
Length = 968
Score = 186 bits (467), Expect = 1e-45
Identities = 252/1015 (24%), Positives = 414/1015 (39%), Gaps = 231/1015 (22%)
Query: 58 TLDEMREKFLKFFEKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPA 117
T E+R++F+ FF+++E H V +P +L A + F+P ++ P+
Sbjct: 6 TASEIRQRFIDFFKRNE---HTYVHSSATIPLDDPTLLFANAGMNQFKPIFLN--TIDPS 60
Query: 118 NPLVI------SQPSIRF----TDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETV 167
+P+ +Q IR D+D+VG H T FEM+ +F Y+ +
Sbjct: 61 HPMAKLSRAANTQKCIRAGGKQNDLDDVGKDVYHHTFFEMLGSWSFGD-----YFKELAC 115
Query: 168 ELAFEFFTKELKMKPEDI------------------------------------TFKENP 191
++A E T+E + E + K+N
Sbjct: 116 KMALELLTQEFGIPIERLYVTYFGGDEAAGLEADLECKQIWQNLGLDDTKILPGNMKDNF 175
Query: 192 WAGG--GNAGPAFEVLY-----------------RGLEVATLVFMQYKKAPENAPEDQVV 232
W G G GP E+ Y LE+ LVF+QY + +
Sbjct: 176 WEMGDTGPCGPCSEIHYDRIGGRDAAHLVNQDDPNVLEIWNLVFIQYNREADG------- 228
Query: 233 IIKGDRYVPMETKVVDTGYGLERLVWMSQGTPTAYDAVLGY-VVEPLKRMAGVEKIDERI 291
I+K P+ K +DTG GLERLV + Q + YD L E +++ G ++
Sbjct: 229 ILK-----PLPKKSIDTGMGLERLVSVLQNKMSNYDTDLFVPYFEAIQKGTGARPYTGKV 283
Query: 292 LMENSRLAGMFDIEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFM 351
E++ + ++ A R +ADH + +T
Sbjct: 284 GAEDA-----------------------------DGIDMAYR------VLADHARTITVA 308
Query: 352 LADGVIPSNVKAGYLARLLIRKSIRHLKEL-----GLEVPLSEIVALHIKELHKTFPEFK 406
LADG P N GY+ R ++R+++R+ E G L ++V ++ L FPE K
Sbjct: 309 LADGGRPDNTGRGYVLRRILRRAVRYAHEKLNASRGFFATLVDVV---VQSLGDAFPELK 365
Query: 407 EMEDVILEIIDLEEKKYSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPE 466
+ D++ +II+ EE ++ +TL RG ++ R+I L IP + Y+++G +
Sbjct: 366 KDPDMVKDIINEEEVQFLKTLSRGRRILDRKIQSLGDS--KTIPGDTAWLLYDTYGFPVD 423
Query: 467 LVKEIAEKEGIKVHVPDNFYSI--VAKEAEKEKEEKEEEVV--DFELVKDLPETRTLYYE 522
L IAE++G+ V + D F +A+ + K E+++ D +++L R L
Sbjct: 424 LTGLIAEEKGLVVDM-DGFEEERKLAQLKSQGKGAGGEDLIMLDIYAIEEL-RARGLEVT 481
Query: 523 DPFMKE-----------FEARVLRVIG----------------DWIVLDQTAFYPEGGGQ 555
D K FE V V+ +VLD+T FY E GGQ
Sbjct: 482 DDSPKYNYHLDSSGSYVFENTVATVMALRREKMFVEEVSTGQECGVVLDKTCFYAEQGGQ 541
Query: 556 PYDTGVLFV------NGSEVKVTNVQKVGKVIVHKVENPGLFKEGMEVRGRIDWDRRIQH 609
YD G L + +E V N Q G ++H G K G +V ID RR
Sbjct: 542 IYDEGYLVKVDDSSEDKTEFTVKNAQVRGGYVLHIGTIYGDLKVGDQVWLFIDEPRRRPI 601
Query: 610 MRHHTGTHVLMGALVRVLGKHVWQAGSQLTTDWARLDISHYKRISDEELREIERLANRIV 669
M +HT TH+L AL VLG+ Q GS + D R D + +S +++++ E +AN ++
Sbjct: 602 MSNHTATHILNFALRSVLGE-ADQKGSLVAPDRLRFDFTAKGAMSTQQIKKAEEIANEMI 660
Query: 670 MEDRKVTWEWLPRTEAEQRYGFRLYQGGVVPGRVIRVVKI--------ED--------WD 713
+ V + P A+ G R P V RVV I +D
Sbjct: 661 EAAKAVYTQDCPLAAAKAIQGLRAVFDETYPDPV-RVVSIGVPVSELLDDPSGPAGSLTS 719
Query: 714 VQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGEAAIKEWQKEREILKKASQVL- 772
V+ CGGTHL ++ G I+ E I G+ RI+ G A K +K E LKK V+
Sbjct: 720 VEFCGGTHLRNSSHAGAFVIVTEEAIAKGIRRIVAVTGAEAQKALRK-AESLKKCLSVME 778
Query: 773 -RVPPEKLPE-------------TAERFFNEW-----KEARKEVEKLKKELAKLLVYELE 813
+V + P A +W +E K ++K+ +L + +++
Sbjct: 779 AKVKAQTAPNKDVQREIADLGEALATAVIPQWQKDELRETLKSLKKVMDDLDRASKADVQ 838
Query: 814 AKV-QKVKEY--------EFIGEIVEG-SMDDLREAVERLK----KPNRIVVLVSKEGYF 859
+V +K K++ I E+ G S L EA++ K + + ++ V E
Sbjct: 839 KRVLEKTKQFIDSNPNQPLVILEMESGASAKALNEALKLFKMHSPQTSAMLFTVDNEAGK 898
Query: 860 AISV------GDNVNLNANDLAKKLTSIAGGGGGGRKDVAQGRIKDVSKAKEAIE 908
+ N L A++ ++++ + G GGG+ AQ K+V +EA++
Sbjct: 899 ITCLCQVPQNAANRGLKASEWVQQVSGLMDGKGGGKDVSAQATGKNVGCLQEALQ 953
>gb|AAF05593.1|AF188718_1 (AF188718) alanyl-tRNA synthetase [Drosophila melanogaster]
Length = 966
Score = 185 bits (464), Expect = 2e-45
Identities = 245/1020 (24%), Positives = 397/1020 (38%), Gaps = 232/1020 (22%)
Query: 55 KKYTLDEMREKFLKFF-EKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEA 113
K T E+R +L FF E+ +Y H +P +L A + F+P + G A
Sbjct: 2 KLLTAKEVRNAYLDFFKEQKHIYVHSS----STIPLDDPTLLFANAGMNQFKP-IFLGTA 56
Query: 114 DPP---------ANPLVISQPSIRFTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWID 164
DP AN + + D+D+VG H T FEM+ + +F Y+
Sbjct: 57 DPNSEMSKWVRVANTQKCIRAGGKHNDLDDVGKDVYHHTFFEMLGNWSFGD-----YFKK 111
Query: 165 ETVELAFEFFTK---------------------------------ELKMKPEDI---TFK 188
E A+EF T+ +L +KPE I + K
Sbjct: 112 EICSWAWEFLTQRLALPKDRLYVTYFGGDAASGLEPDLECKQMWLDLGLKPEHILPGSMK 171
Query: 189 ENPWAGG--GNAGPAFEVLYRG-----------------LEVATLVFMQYKKAPENAPED 229
+N W G G GP E+ + LE+ LVF+QY + + + +
Sbjct: 172 DNFWEMGETGPCGPCSELHFDRIGGRSVPELVNMDDPDVLEIWNLVFIQYNRESDGSLKQ 231
Query: 230 QVVIIKGDRYVPMETKVVDTGYGLERLVWMSQGTPTAYDAVLGYVVE-PLKRMAGVEKID 288
+ K +D G G ERLV + Q + YD L + P KR +
Sbjct: 232 ------------LPKKHIDCGMGFERLVSVIQNKRSNYDTDLFVPLSMPSKRALVPQPYQ 279
Query: 289 ERILMENSRLAGMFDIEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKAL 348
R+ ++ V+ ++ A R +ADH + +
Sbjct: 280 GRVGADD-----------------------------VDGIDMAYR------VLADHARTI 304
Query: 349 TFMLADGVIPSNVKAGYLARLLIRKSIRHLKELGLEVP--LSEIVALHIKELHKTFPEFK 406
T LADG P N GY+ R ++R+++R+ E P + +V + L FPE K
Sbjct: 305 TIALADGGTPDNTGRGYVLRRILRRAVRYATEKLNAKPGFFATLVNTVVDLLGDAFPEVK 364
Query: 407 EMEDVILEIIDLEEKKYSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPE 466
+ I++II+ EE ++ +TL RG +L+ R I KL + + IP + Y+++G +
Sbjct: 365 KDPQHIIDIINEEELQFLKTLTRGRNLLNRTIEKLGNQ--TTIPGDVAWRLYDTYGFPVD 422
Query: 467 LVKEIAEKEGIKVHVPDNF----YSIVAKEAEKEKEEKEEEVVDFELVKDLPETRTLYYE 522
L + +AE++ +K+ + D + ++ K + EE +D + L E
Sbjct: 423 LTQLMAEEKSLKIDM-DGYEAAKHNSYVLSQGKGASKIEEINLDVHAISQLQEQGVPPTN 481
Query: 523 DPFMKEFEAR------------------VLRVIGDW-----------IVLDQTAFYPEGG 553
D F ++EA LR + IVLD+T FY E G
Sbjct: 482 DTFKYKYEAVSDERDSAYNYGVCNSKIVALRFENQFVNEITSGQKAGIVLDKTNFYAESG 541
Query: 554 GQPYDTGVLF-VN--GSEVKVTNVQKVGKVIVHKVENPGLFKEGMEVRGRIDWDRRIQHM 610
GQ YD G L VN +E V V G I+H G K G E+ ID +RR M
Sbjct: 542 GQIYDQGALVKVNDEANEFLVDRVYNRGGYILHIGVVEGTLKVGDELELHIDVERRWLTM 601
Query: 611 RHHTGTHVLMGALVRVLGKHVWQAGSQLTTDWARLDISHYKRISDEELREIERLANRIVM 670
++H+ TH L L++VLGK Q GS + + R D + + L +V
Sbjct: 602 KNHSATHALNHCLLQVLGKDTEQKGSLVVPEKLRFDFNSKAAMPSSRCPRRSSLTKEMVY 661
Query: 671 EDRKVTWEWLPRTEAEQRYGFRLYQGGVVPGRVIRVVKI----------------EDWDV 714
++ + + A++ G R V P V RV+ E V
Sbjct: 662 KNVPIYAKESKLALAKKIRGLRSVFDEVYPDPV-RVISFGVPVDELEQNPDSEAGEQTSV 720
Query: 715 QACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGEAAIKEWQK----EREILK---- 766
+ CGGTHL +G + I E I G+ RI+ G A+K +K E+EI++
Sbjct: 721 EFCGGTHLRRSGHIMDFVISSEEAIAKGIRRIVALTGPEALKALKKSEAFEQEIVRLKAT 780
Query: 767 ----KASQVLRVPPEKLPETAERF------FNEWKEARKEVEKLKKEL------------ 804
K+ + + +++ E E+ + + E R ++ LKK L
Sbjct: 781 IDNDKSGKDSKSHVKEIVELTEQISHATIPYVKKDEMRNLLKGLKKTLDDKERALRAAVS 840
Query: 805 ----------------AKLLVYELEAKVQKVKEYEFIGEIVEGSMDDLREAVERLKKPNR 848
A +LV +LEA K + + V + D + ++
Sbjct: 841 VTVVERAKTLCEANPNATVLVEQLEA-FNNTKALDAALKQVRSQLPDAAAMFLSVDADSK 899
Query: 849 IVVLVSKEGYFAISVGDNVNLNANDLAKKLTSIAGGGGGGRKDVAQGRIKDVSKAKEAIE 908
+ +S A+ G L AN+ + +++ GG GGG+ + AQ + K E ++
Sbjct: 900 KIFCLSSVPKSAVEKG----LKANEWVQHVSATLGGKGGGKPESAQASGTNYEKVDEIVQ 955
>sp|P96041|SYA_SULSO ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|1814431|gb|AAB99528.1| (U85262) alanyl-tRNA
synthetase [Sulfolobus solfataricus]
Length = 174
Score = 182 bits (457), Expect = 2e-44
Identities = 93/169 (55%), Positives = 107/169 (63%), Gaps = 4/169 (2%)
Query: 6 KTRMFEEEGWIRKKCKVCGKPFWTLDPDRETCGDPPCDEYQFIGKPGIPKKYTLDEMREK 65
K F + + RK CK C PFWT D +E C D PC +Y F + T+ E REK
Sbjct: 9 KLNFFIKNDFKRKICKSCQTPFWTKDDKKEYCSDIPCTDYYFFDINIKSQPLTVKEAREK 68
Query: 66 FLKFFEKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPANPLVISQP 125
FL FFEK H R+ PVL RWR+D+ L ASI+DFQP V SG PPANPLV+SQP
Sbjct: 69 FLSFFEKRG---HTRIPPKPVLARWREDLYLTIASIVDFQPHVTSGLVPPPANPLVVSQP 125
Query: 126 SIRFTDIDNVGIT-GRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFEF 173
SIR DIDNVG+T GRH T FEM AHHAFNYP + +YW DET A EF
Sbjct: 126 SIRLEDIDNVGVTFGRHLTTFEMAAHHAFNYPDRYVYWKDETTAYATEF 174
>pir||D82899 alanyl-tRNA synthetase UU369 [imported] - Ureaplasma urealyticum
>gi|6899351|gb|AAF30778.1|AE002134_2 (AE002134)
alanyl-tRNA synthetase [Ureaplasma urealyticum]
Length = 906
Score = 181 bits (455), Expect = 3e-44
Identities = 222/979 (22%), Positives = 395/979 (39%), Gaps = 202/979 (20%)
Query: 56 KYTLDEMREKFLKFFEKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADP 115
K + +E+R+K+++FFE + H ++ ++P+ +L + + + + + SG+ P
Sbjct: 3 KLSTNEIRKKWIEFFESKD---HLFIEPKSLIPKNDPTLLWINSGVSTLKDY-FSGKVKP 58
Query: 116 PANPLVISQPSIRFTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFEFFT 175
P LV SQ +IR DI NVG+T RH T FEM+ + + Y+ E ++ A+EF
Sbjct: 59 PHKRLVNSQKAIRTNDIFNVGLTSRHHTFFEMLGNFSIG-----DYFKKEAIDWAYEFLI 113
Query: 176 KELKMKP--------EDITFKENPW---------------------AGGGNAGPAFEVLY 206
LK+ ED F + W G G GP E+ Y
Sbjct: 114 NVLKIDVKKLWVTVFEDDQFTNDEWIKLGIIKEQIIKCNRDRNFWDVGNGPCGPCTEIHY 173
Query: 207 -----------------------RGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYVPME 243
R +E+ +VF Q+ N Y +
Sbjct: 174 DRGERFDPNKIGSKLILEDIENDRYVEIWNIVFSQFNNDGHN------------NYTELL 221
Query: 244 TKVVDTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSRLAGMFD 303
K +DTG GLER+ +SQ PT +D+ + ++ VE+ E +D
Sbjct: 222 QKNIDTGAGLERIACISQDVPTNFDSDVF-----MRITKSVEQFSEY----------KYD 266
Query: 304 IEDMGDLKLLRKKV--AEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSNV 361
+ + + + K+ A KV IADH +A F +ADG IPSN
Sbjct: 267 MNEYFHPNVTQNKINFAYKV-------------------IADHMRATVFAIADGAIPSNK 307
Query: 362 KAGYLARLLIRKSIRHLKELGLEVPL-----SEIVALHIKELHKTFPEFKEMEDVILEII 416
+ GY+ R LIR+++ ++ L + L + +A + + + + K + + + I+
Sbjct: 308 ERGYILRRLIRRTMVLVRRLNINNLLWVDAVVDAIASTMGDFYTYLKDEKTLTKIKM-IL 366
Query: 417 DLEEKKYSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITF--YESHGLTPELVKEIAEK 474
+ E + + +TL+ G ++ I + L+K ITF +++G EL+KEI E+
Sbjct: 367 NKEVQLFEKTLQLGLNIFENSIRNQE--------LDKEITFKLVDTYGFPIELIKEICEQ 418
Query: 475 EGIKVHVPD-----NFYSIVAKEAEKEKEEKEEEVVDFELVKDLPETRTLYYEDPFMKEF 529
+KV + + +++K + + E + E + L T +YE +
Sbjct: 419 RNVKVDLEAFDAMFKHHQLISKANKANLKVMESQ---NESLMQLDVDSTFHYE--IFRWE 473
Query: 530 EARVLRVIGD-------------WIVLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTNVQK 576
A+++ + + ++V D T FY GGQ +DTG + N + V +V K
Sbjct: 474 NAKIITLFNEDFELVDGLDHEDGYVVFDNTCFYATSGGQQHDTGYIIKNDQQFFVDDVFK 533
Query: 577 V-GKVIVHKVENPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAG 635
+ VH V+N L + + DR+ +HT H+L L VL + Q G
Sbjct: 534 APNRQHVHHVKNASLSMNEHVILQINEQDRK-SITANHTAEHLLHYCLKHVLSPDIKQEG 592
Query: 636 SQLTTDWARLDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFRLYQ 695
+ D +++ + + +L ++E + N +V + V + EA + G Y
Sbjct: 593 AAKYPHKVTFDFTYHAQPTKAQLDKLENVLNEMVQSNFDVQELHMDLDEA-KAVGAAAYF 651
Query: 696 GGV---VPGRVIRVVKIEDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGE 752
V + G+ +RV+K+ ++ CGGTH T + IKI+ G RI G
Sbjct: 652 EDVYKKLKGK-LRVIKMGP-SIELCGGTHAHHTSEIERIKIVECASKGAGSWRITMVTGH 709
Query: 753 AAIKEWQKEREI-----LKKASQVLRVPPEKLPETAERFFNEWKEARKE-----VEKLKK 802
+ ++ + + + L + KL + F N WK + EK +
Sbjct: 710 DNLAKYIHDLYVDYLNEINHLKVNLDINDHKLNDLYNAFAN-WKNLSIDDYDLLNEKFAE 768
Query: 803 ELAKLLVYELEAKVQKVKE-----------------------------YEFIGEIVEGSM 833
L+ +++E Q K+ + + E++ +
Sbjct: 769 LKQSLINFKIEFDKQNAKQAIIDIKNTFNTQLTNKRVHVFKNTDNKNIFNALNELINENQ 828
Query: 834 DDLREAVERLKKPNRIVVLVSKEGYFAISVGDNVNLNANDLAKKLTSIAGGGGGGRKDVA 893
D L + N+I L++ FA + +N N K+L +I+ G GGG+
Sbjct: 829 DTL--FISFNLDDNKIQYLLAINEKFATT----NQINLNKYIKELNTISNGKGGGKPYFV 882
Query: 894 QGRIKDVSKAKEAIESIVK 912
QG + K E + + K
Sbjct: 883 QGGTSEQEKLDELLTVVDK 901
>gi|11431793 alanyl-tRNA synthetase [Homo sapiens]
Length = 987
Score = 171 bits (429), Expect = 3e-41
Identities = 214/834 (25%), Positives = 336/834 (39%), Gaps = 206/834 (24%)
Query: 128 RFTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFEFFTKELKMKPEDI-- 185
+ D+D+VG H T FEM+ +F Y+ + ++A E T+E + E +
Sbjct: 162 KHNDLDDVGKDVYHHTFFEMLGSWSFGD-----YFKELACKMALELLTQEFGIPIERLYV 216
Query: 186 ----------------------------------TFKENPWAGG--GNAGPAFEVLY--- 206
K+N W G G GP E+ Y
Sbjct: 217 TYFGGDEAAGLEADLECKQIWQNLGLDDTKILPGNMKDNFWEMGDTGPCGPCSEIHYDRI 276
Query: 207 --------------RGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYVPMETKVVDTGYG 252
LE+ LVF+QY + + I+K P+ K +DTG G
Sbjct: 277 GGRDAAHLVNQDDPNVLEIWNLVFIQYNREADG-------ILK-----PLPKKSIDTGMG 324
Query: 253 LERLVWMSQGTPTAYDAVLGY-VVEPLKRMAGVEKIDERILMENSRLAGMFDIEDMGDLK 311
LERLV + Q + YD L E +++ G ++ E++
Sbjct: 325 LERLVSVLQNKMSNYDTDLFVPYFEAIQKGTGARPYTGKVGAEDA--------------- 369
Query: 312 LLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSNVKAGYLARLLI 371
+ ++ A R +ADH + +T LADG P N GY+ R ++
Sbjct: 370 --------------DGIDMAYR------VLADHARTITVALADGGRPDNTGRGYVLRRIL 409
Query: 372 RKSIRHLKEL-----GLEVPLSEIVALHIKELHKTFPEFKEMEDVILEIIDLEEKKYSET 426
R+++R+ E G L ++V ++ L FPE K+ D++ +II+ EE ++ +T
Sbjct: 410 RRAVRYAHEKLNASRGFFATLVDVV---VQSLGDAFPELKKDPDMVKDIINEEEVQFLKT 466
Query: 427 LKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKVHVPDNFY 486
L RG ++ R+I L IP + Y+++G +L IAE++G+ V + D F
Sbjct: 467 LSRGRRILDRKIQSLGDS--KTIPGDTAWLLYDTYGFPVDLTGLIAEEKGLVVDM-DGFE 523
Query: 487 SI--VAKEAEKEKEEKEEEVV--DFELVKDLPETRTLYYEDPFMKE-----------FEA 531
+A+ + K E+++ D +++L R L D K FE
Sbjct: 524 EERKLAQLKSQGKGAGGEDLIMLDIYAIEEL-RARGLEVTDDSPKYNYHLDSSGSYVFEN 582
Query: 532 RVLRVIG----------------DWIVLDQTAFYPEGGGQPYDTGVLFV------NGSEV 569
V V+ +VLD+T FY E GGQ YD G L + +E
Sbjct: 583 TVATVMALRREKMFVEEVSTGQECGVVLDKTCFYAEQGGQIYDEGYLVKVDDSSEDKTEF 642
Query: 570 KVTNVQKVGKVIVHKVENPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGK 629
V N Q G ++H G K G +V ID RR M +HT TH+L AL VLG+
Sbjct: 643 TVKNAQVRGGYVLHIGTIYGDLKVGDQVWLFIDEPRRRPIMSNHTATHILNFALRSVLGE 702
Query: 630 HVWQAGSQLTTDWARLDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRY 689
Q GS + D R D + +S +++++ E +AN ++ + V + P A+
Sbjct: 703 -ADQKGSLVAPDRLRFDFTAKGAMSTQQIKKAEEIANEMIEAAKAVYTQDCPLAAAKAIQ 761
Query: 690 GFRLYQGGVVPGRVIRVVKI--------ED--------WDVQACGGTHLPSTGLVGPIKI 733
G R P V RVV I +D V+ CGGTHL ++ G I
Sbjct: 762 GLRAVFDETYPDPV-RVVSIGVPVSELLDDPSGPAGSLTSVEFCGGTHLRNSSHAGAFVI 820
Query: 734 LRTERIQDGVERIIFACGEAAIKEWQKEREILKKASQVL--RVPPEKLPETAERFFNEWK 791
+ E I G+ RI+ G A K +K E LKK V+ +V + P K
Sbjct: 821 VTEEAIAKGIRRIVAVTGAEAQKALRK-AESLKKCLSVMEAKVKAQTAPN---------K 870
Query: 792 EARKEVEKLKKELAKLLVYELEAKVQKVKEYEFIGEIVEGSMDDLREAVERLKK 845
+ ++E+ L + LA + I + D+LRE ++ LKK
Sbjct: 871 DVQREIADLGEALATAV-------------------IPQWQKDELRETLKSLKK 905
>pir||A71213 alanine--tRNA ligase truncated homolog PH1969 - Pyrococcus
horikoshii >gi|3258413|dbj|BAA31096.1| (AP000007) 404aa
long hypothetical alanyl-tRNA synthetase [Pyrococcus
horikoshii]
Length = 404
Score = 170 bits (427), Expect = 5e-41
Identities = 120/389 (30%), Positives = 200/389 (50%), Gaps = 18/389 (4%)
Query: 519 LYYEDPFMKEFEARVLRVIGDW----IVLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTN- 573
+YY+DP+++E +A+++ V + +VLD+T FYPEGGGQP D GV+ N E+ V +
Sbjct: 5 VYYKDPYLREIDAKIVDVRKEKDRVEVVLDRTIFYPEGGGQPGDRGVIKGNDFEIMVEDT 64
Query: 574 VQKVGKVIVHKVENPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQ 633
++K G++ + KEG +V+ +DW+ R +M+ HTG H+L L ++
Sbjct: 65 IEKNGEIFHIGKLRGEIPKEGEKVKLYLDWEWRYGNMQMHTGQHILSAVLKKLYDLDT-- 122
Query: 634 AGSQLTTDWARLDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFRL 693
G + D+A+++++ E E+E N+I++ D V E + E +L
Sbjct: 123 TGFNIFRDYAKIEVNGEVNWDMIERAELE--VNKIIINDLPVVIEEYDKLPEE--IALKL 178
Query: 694 YQGGVVPGRVIRVVKIEDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGEA 753
+ IR+VKI D DV CGGTH+ ST VG IK+LR + + RI F CG
Sbjct: 179 RKNVTKVKEKIRIVKIGDVDVTPCGGTHVKSTREVGIIKVLRFYKKSKNLWRIEFTCGYR 238
Query: 754 AIKEWQKEREILKKASQVLRVPPEKLPETAERF---FNEWKEARKEVEKLKKELAKLLVY 810
AI K EIL+ L + P K P ER +E+L++E+ +
Sbjct: 239 AI---SKMNEILRDYWGSLDLMPNKNPPLIERINEVLRTVNSLENRIEELRREIWEWKGK 295
Query: 811 ELEAKVQKVKEYEFIGEIVEGSMDDLRE-AVERLKKPNRIVVLVSKEGYFAISVGDNVNL 869
L + KV Y I + +M D + A++ +KK + ++L++ E Y + + V +
Sbjct: 296 ALLKEGVKVGNYTVITHVENWNMKDAQAFAIDFVKKNSNTILLLANEKYVLFAKNEGVPV 355
Query: 870 NANDLAKKLTSIAGGGGGGRKDVAQGRIK 898
+ +L K++ GG GGG ++A+GR++
Sbjct: 356 SMRELLKEVIDELGGKGGGTDNLARGRVE 384
>dbj|BAA86584.1| (AB033096) KIAA1270 protein [Homo sapiens]
Length = 986
Score = 166 bits (416), Expect = 1e-39
Identities = 202/829 (24%), Positives = 333/829 (39%), Gaps = 174/829 (20%)
Query: 62 MREKFLKFFEKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPANP-- 119
+R FL FF + H V V PR +L V A + F+P + G DP +
Sbjct: 43 VRAAFLNFFRDR--HGHRLVPSASVRPRGDPSLLFVNAGMNQFKP-IFLGTVDPRSEMAG 99
Query: 120 ---LVISQPSIR----FTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFE 172
+ SQ +R D+++VG H T FEM+ + AF Y+ +E +A+E
Sbjct: 100 FRRVANSQKCVRAGGHHNDLEDVGRDLSHHTFFEMLGNWAFGGE----YFKEEACNMAWE 155
Query: 173 FFTKELKMKPEDITF------------------------------------KENPWAGG- 195
T+ + E + +EN W G
Sbjct: 156 LLTQVYGIPEERLWISYFDGDPKAGLDPDLETRDIWLSLGVPASRVLSFGPQENFWEMGD 215
Query: 196 -GNAGPAFEVLY---------RGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYVPMETK 245
G GP E+ Y + +E+ LVFMQ+ + + + + P+ +
Sbjct: 216 TGPCGPCTEIHYDLAGGVGAPQLVELWNLVFMQHNREADGSLQ------------PLPQR 263
Query: 246 VVDTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSRLAGMFDIE 305
VDTG GLERLV + QG + YD L PL N+ G
Sbjct: 264 HVDTGMGLERLVAVLQGKHSTYDTDL---FSPLL---------------NAIQQGCRAPP 305
Query: 306 DMGDLKLLRKKVAEKVGISVE-ELEKAIRPYELIYAIADHTKALTFMLADGVIPSNVKAG 364
+G +VG++ E + A R +ADH + L+ ++DGV P
Sbjct: 306 YLG-----------RVGVADEGRTDTAYR------VVADHIRTLSVCISDGVFPGMSGPP 348
Query: 365 YLARLLIRKSIRHLKELGLEVP---LSEIVALHIKELHKTFPEFKEMEDVILEIIDLEEK 421
+ R ++R+++R E+ L+ P L +V + ++ L +PE + I ++ +E
Sbjct: 349 LVLRRILRRAVRFSMEI-LKAPPGFLGSLVPVVVETLGDAYPELQRNSAQIANLVSEDEA 407
Query: 422 KYSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKVHV 481
+ +L+RG ++ R + L M + ++ GL ++V+ + E++G+++
Sbjct: 408 AFLASLERGRRIIDRTLRTLGPSDMFPAEVAWSLSLCGDLGLPLDMVELMLEEKGVQLDS 467
Query: 482 PDNFYSIVAKEAEKEKEEKEEEV------VDFELVKDLPETRTLYYEDPFMKEF------ 529
+A+E + + + E V +D + +L +D +
Sbjct: 468 AG--LERLAQEEAQHRARQAEPVQKQGLWLDVHALGELQRQGVPPTDDSPKYNYSLRPSG 525
Query: 530 -------EARVLRVIGD--------------WIVLDQTAFYPEGGGQPYDTGVLFVNGSE 568
EA+VL++ + ++LD+T FY E GGQ D G L G E
Sbjct: 526 SYEFGTCEAQVLQLYTEDGTAVASVGKGQRCGLLLDRTNFYAEQGGQASDRGYLVRAGQE 585
Query: 569 ---VKVTNVQKVGKVIVHKVENPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVR 625
V Q G I+H+ P + G +V+ +D R+ M HT TH+L AL +
Sbjct: 586 DVLFPVARAQVCGGFILHEAVAPECLRLGDQVQLHVDEAWRLGCMAKHTATHLLNWALRQ 645
Query: 626 VLGKHVWQAGSQLTTDWARLDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEA 685
LG Q GS L + RLD++ ++ E+LR +E V +D V E +P
Sbjct: 646 TLGPGTEQQGSHLNPEQLRLDVTTQTPLTPEQLRAVENTVQEAVGQDEAVYMEEVPLALT 705
Query: 686 EQRYGFRLYQGGVVPGRVIRVVKIE---------------DWDVQACGGTHLPSTGLVGP 730
Q G R V P V RVV + V+ C GTHL TG VG
Sbjct: 706 AQVPGLRSLD-EVYPDPV-RVVSVGVPVAHALDPASQAALQTSVELCCGTHLLRTGAVGD 763
Query: 731 IKILRTERIQDGVERIIFACGEAAIKEWQKEREILKKASQVLRVPPEKL 779
+ I+ ++ G R++ GE A Q+ RE+ + +Q ++ E+L
Sbjct: 764 LVIIGDRQLSKGTTRLLAVTGEQA----QQARELGQSLAQEVKAATERL 808
>pir||G75027 alanyl-tRNA synthetase related protein PAB1190 - Pyrococcus abyssi
(strain Orsay) >gi|5459175|emb|CAB50661.1| (AJ248288)
alanyl-tRNA synthetase related protein (fragment)
[Pyrococcus abyssi]
Length = 405
Score = 157 bits (392), Expect = 7e-37
Identities = 126/411 (30%), Positives = 213/411 (51%), Gaps = 27/411 (6%)
Query: 517 RTLYYEDPFMKEFEARV--LRVIGDWIV--LDQTAFYPEGGGQPYDTGVLFVNGSEVKVT 572
R LYY DP++K +A++ L + GD I L +T FYP GGGQP D G + +G E+ V
Sbjct: 3 RKLYYVDPYLKTAKAKISDLTIKGDKIEVSLTETIFYPRGGGQPGDKGKIRGDGFEIIVE 62
Query: 573 NVQKVGKVIVHKVENPGLFKE-GMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHV 631
+ + I H + G E G EV +DW+ R +M+ HTG H+L L +
Sbjct: 63 DTVERDGEIWHVGKLNGRTPEVGEEVELELDWEWRYGNMQMHTGQHILSAVLKKRYDLDT 122
Query: 632 WQAGSQLTTDWARLDISHYKRISDEELREIERLANRIVMEDRKVT---WEWLPRTEAEQR 688
+G + D+A+++++ ++ E + E E AN+++++D V +E LP+ E+
Sbjct: 123 --SGFNIFGDYAKIEVNG--ELNWEMIEEAELEANKVIIDDLPVRVEEYEVLPKGVVEK- 177
Query: 689 YGFRLYQGGVVPGRVIRVVKI-EDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERII 747
R Y + G+ IR+V+I E++D+ CGGTH+ ST VG IK+LR + RI
Sbjct: 178 --LRKYIPNI-KGK-IRIVRIGENFDLTPCGGTHVKSTREVGVIKVLRFYKKSKDTWRIE 233
Query: 748 FACGEAAIKEWQKEREILKKASQVLRVPPEKLPETAER---FFNEWKEARKEVEKLKKEL 804
F CG AIK K EILK L P K P +ER + ++V+ ++KE+
Sbjct: 234 FTCGFRAIK---KLNEILKDYWSALDAMPNKNPPLSERVREVLESVESLEEKVDSMRKEV 290
Query: 805 AKLLVYELEAKVQKVKEYEFIGEIVEGSMDDLRE-AVERLKKPNRIVVLVSKEGYFAISV 863
K L + ++ Y + + + + D + AV+ +K +V+++ E Y ++
Sbjct: 291 WKWKEESLLGRSIEIGHYNVVTFVEKWDIKDAQAFAVDFVKNNPGTIVVLASEDYVILAR 350
Query: 864 GDNVNLNANDLAKKLTSIAGGGGGGRKDVAQGRIKDVSKAKEAIESIVKLL 914
+ V ++ L + L GG GGG ++A+G+I+ ++ ++ I+ +V L
Sbjct: 351 NEEVEVSMKSLLEDLIKEFGGKGGGTDNLARGKIE--AEPEDVIDFVVDRL 399
>emb|CAC11271.1| (AL445063) alanyl-tRNA synthetase related protein [Thermoplasma
acidophilum]
Length = 245
Score = 151 bits (378), Expect = 3e-35
Identities = 91/245 (37%), Positives = 135/245 (54%), Gaps = 12/245 (4%)
Query: 516 TRTLYYEDPFMKEFEARVLRVIGDWIVLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTNVQ 575
T LYY+D +MKEF+A V+ V + IVLD+TAFYP GGGQP DTG++ + +V +VQ
Sbjct: 6 TEKLYYDDMYMKEFQAEVVSVDSNGIVLDRTAFYPTGGGQPNDTGIIVNDDKTYRVVDVQ 65
Query: 576 KVGKVIVHKVENPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAG 635
K G +VH +E+ K G + G+IDW+RR HMR+HT H+L G + G
Sbjct: 66 KHGDDVVHILESVDGLKAGDRIYGKIDWERRYAHMRYHTAIHILDGIVSAKHNSEALLTG 125
Query: 636 SQLTTDWARLDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFRLYQ 695
Q+ D +R+D+ + + + E + +I + AN + E +V E + R EA +R +
Sbjct: 126 GQIYEDRSRIDM-NIENFTKEFVDQIIQEANEFISEGHRVYAENISREEAMKRPNLARTE 184
Query: 696 GGVVPGR-------VIRVVKIEDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIF 748
PGR V+R++ IE D Q+ GGTH+ +T VG I + + E +RI F
Sbjct: 185 ----PGRKLIESLPVVRIIVIEGLDEQSDGGTHVANTREVGKIVLRKIENKGRKNKRIEF 240
Query: 749 ACGEA 753
A
Sbjct: 241 ELSPA 245
>sp|P47534|SYA_MYCGE ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|1361443|pir||C64232 alanine--tRNA ligase (EC
6.1.1.7) - Mycoplasma genitalium
>gi|3844871|gb|AAC71513.1| (U39709) alanyl-tRNA
synthetase (alaS) [Mycoplasma genitalium]
Length = 900
Score = 145 bits (363), Expect = 2e-33
Identities = 180/843 (21%), Positives = 338/843 (39%), Gaps = 135/843 (16%)
Query: 57 YTLDEMREKFLKFFEKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPP 116
+T D++R+ +L +F K + H + ++P +L + + + + + S PP
Sbjct: 3 WTTDKVRQTWLDYFAKKD---HLVLASKSLIPINDPSLLWINSGVATLKDY-FSARKTPP 58
Query: 117 ANPLVISQPSIRFTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFEFFTK 176
+ LV +Q +R DI+NVG T RH T+FEM+ + + Y+ E ++ AF+
Sbjct: 59 SKRLVNAQICLRVNDIENVGFTSRHQTLFEMLGNFSIGD-----YFKTEAIDFAFDLLVN 113
Query: 177 ELKMKP----------EDITFKE------------------NPW-AGGGNAGPAFEVLYR 207
++ P ++ T+K N W G G GP E+ Y
Sbjct: 114 YYQLDPKRFYITVYEDDETTYKRWIKHKIDKNHIIKCDKSRNFWDLGLGPCGPCTEIYYD 173
Query: 208 GLEVATLVFMQYKKAPENAPEDQVVII-----------KGDRYVPMETKVVDTGYGLERL 256
E + K E+ D+ V I Y + K +DTG G+ERL
Sbjct: 174 RGEKFDPKKIGEKLFFEDIENDRYVEIWNIVFSQFNNDGNGNYTELAQKNIDTGAGIERL 233
Query: 257 VWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSRLAGMFDIEDMGDLKLLRKK 316
V + Q +PT +D + LK + +E NS FD + + + R
Sbjct: 234 VSVLQNSPTNFDTDIF-----LKLIKIIEAFCPFKYDPNSYFT--FDPQKVKEQSYFR-- 284
Query: 317 VAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSNVKAGYLARLLIRKSIR 376
IADH KA+TF +++GV+P + Y+ R L+R+++
Sbjct: 285 -----------------------IIADHFKAITFTISEGVLPGPNERNYVVRRLLRRALI 321
Query: 377 HLKELGLEVP-LSEIVALHIKELHKTFPEFKEMEDVILEIIDLEEKKYSETLKRGSDLVR 435
K+L L + + +I+ I + K + + +++ E +++T+ G
Sbjct: 322 ACKKLQLNLAFIEKIIDEIIASYENYYQHLKAKNETVKQVVLKEINAFNKTIDLG----- 376
Query: 436 REIAKLKKKGMSEIPLEKLITFY--ESHGLTPELVKEIAEKEGIKVHVPDNFYSIVAKEA 493
L +K + L +TF E++G E+++E+ ++G+ + F ++AK
Sbjct: 377 ---LVLFEKSVKNNTLTPQLTFQLNETYGFPVEIIRELVNQKGLTIDW-TVFDQLMAKHR 432
Query: 494 EKEKEEKEE---EVVDFELVKDLPETRTLYYEDPFMKE----FEARVLRV-----IGDWI 541
K+ + E + LV ++ Y+++ + F+ L V ++
Sbjct: 433 SISKQNNQTINFEKQNINLVNFKTKSTFFYHKNKINAKVIGLFDENYLPVKELNNQSGYV 492
Query: 542 VLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTNVQKVGKVIVHKVENP--------GLFKE 593
V DQT Y GGQ YD G +N S N QK+ V K N G FK
Sbjct: 493 VFDQTVLYATSGGQRYDEGSC-INHSN---NNDQKISFQGVFKGPNKQHFHYFLVGSFKL 548
Query: 594 GMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTTDWARLDISHYKRI 653
+V D R +H+ H+L AL + + + Q+G+ + A +D + + +
Sbjct: 549 NDQVTLSHDETWRKLAANNHSLEHLLHAALQKEIDPLIKQSGAFKSAQKATIDFNLNRHL 608
Query: 654 SDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFRLYQGGVVPGRVIRVVKIEDWD 713
+ EL ++E ++ + + +++ ++ ++RV++ D+
Sbjct: 609 TRNELEKVENKIRSLIKQKISSKEIFTDFEGSQKLNAIAYFEEEYSQHEILRVIRFGDYS 668
Query: 714 VQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGEAAIKEWQK------------- 760
V+ CGGTH+ +T + I + G RI I + K
Sbjct: 669 VELCGGTHVANTASIEDCFITDFYSLGAGRWRIEIISSNETINNYLKAENQKLIQLKSEL 728
Query: 761 EREILKKASQVLRVPPEKLPETAERFFNEWKEARKEVEKLKKELAKLLVYELEAKVQKVK 820
E+ + S + +V ++L + ++F +++ +L+ LL + + K K
Sbjct: 729 EKVLSLIDSSIFKVELKELQQRLDKFI-----LPEKITQLRDASDTLLALKNDINQLKTK 783
Query: 821 EYE 823
Y+
Sbjct: 784 NYK 786
>sp|P75368|SYA_MYCPN ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|2146058|pir||S73748 alanine--tRNA ligase (EC
6.1.1.7) alaS - Mycoplasma pneumoniae (strain ATCC
29342) >gi|1674107|gb|AAB96070.1| (AE000041) alanyl-tRNA
synthetase [Mycoplasma pneumoniae]
Length = 900
Score = 144 bits (360), Expect = 4e-33
Identities = 191/890 (21%), Positives = 352/890 (39%), Gaps = 169/890 (18%)
Query: 56 KYTLDEMREKFLKFFEKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADP 115
K+T D++R+ +L +F H + ++P +L + + + + + S + P
Sbjct: 2 KWTTDKVRQTWLDYFTAKG---HLALPSKSLIPVNDPSLLWINSGVATLKDY-FSAKKTP 57
Query: 116 PANPLVISQPSIRFTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFEFFT 175
P+ L +Q +R DI+NVG T RH T+FEM+ + + Y+ +E + A +
Sbjct: 58 PSKRLANAQICLRVNDIENVGFTSRHQTLFEMLGNFSIGD-----YFKEEAIGFANDLLV 112
Query: 176 KELKMKP----------EDITFK------------------ENPW-AGGGNAGPAFEVLY 206
+ P +++TF N W G G GP E+ Y
Sbjct: 113 NHYHLDPKRFYITVYQDDELTFNTWLKHGIPASRIIKCDRDRNFWDLGLGPCGPCTEIYY 172
Query: 207 -----------------------RGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYVPME 243
R +EV +VF Q+ Y +
Sbjct: 173 DRGERFDPHKVGEKLFFEDIENDRYVEVWNIVFSQFNNDGNG------------NYSELA 220
Query: 244 TKVVDTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSRLAGMFD 303
K +DTG G+ERLV + Q PT +D + + + K D + + FD
Sbjct: 221 QKNIDTGAGIERLVAILQDAPTNFDTDIFLKLIGIIEQHCKHKYDTNLYFK-------FD 273
Query: 304 IEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSNVKA 363
+ + E + A R I+DH KA+TF +A+GV+P +
Sbjct: 274 QK-------------------LNEAQSAFR------IISDHFKAITFTIAEGVLPGPNER 308
Query: 364 GYLARLLIRKSIRHLKELGLEVP-LSEIVALHIKELHKTFPEFKEMEDVILEIIDLEEKK 422
Y+ R L+R+++ K+L L++ + +V I + + + V+ + I E
Sbjct: 309 SYIVRRLLRRALLACKKLDLDLKFIDPMVDAIISVYGSYYQQLQGKNQVVQQAIWKEVTA 368
Query: 423 YSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKVHVP 482
+ +T+ G L + IA + + + YE++G E++KE+ +K ++V
Sbjct: 369 FDKTINLGLMLFEKSIAH------NALQPQVAFQLYETYGFPIEMIKELVDKRQLQVDWK 422
Query: 483 D-----NFYSIVAKEAEK--EKEEKEEEVVDFELVKDLPETRTLYYEDPFMKEFEARVLR 535
+ +++K+ E++ E +V+F+ + YE E A+V+
Sbjct: 423 AVEQLMEQHRLISKQNSNTLSFEKQNEHLVNFKTASE------FLYE---ANEITAKVIG 473
Query: 536 VIGD-------------WIVLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTNVQKVGKVIV 582
+ + ++V DQT Y GGQ YD G +N S+ N Q+V V
Sbjct: 474 LFDEQYQPVQKLHNQSGYVVFDQTVLYATSGGQRYDEGYC-INHSQ----NDQRVSFQGV 528
Query: 583 HKVEN--------PGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQA 634
K N G F+ G +V D R +H+ H+L AL + + Q
Sbjct: 529 FKGPNKQHFHFFLTGSFQLGDKVILVHDGKWRQLVKNNHSLEHLLHAALQNEIDPLIKQD 588
Query: 635 GSQLTTDWARLDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFRLY 694
G+ + A +D + + ++ EL +E +I+ +D + + +++ +
Sbjct: 589 GAFKSAQKATIDFNFSRALTWAELERVEHRIRQIIQQDIQREEIFTDLEGSQKLNAIAYF 648
Query: 695 QGGVVPGRVIRVVKIEDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGEAA 754
+ ++RV++ D+ V+ CGGTH+ TGL+ I G RI
Sbjct: 649 EEEYSNHELLRVIRFGDFSVELCGGTHVEHTGLIENCFITDYYARGTGRWRIEIISSNET 708
Query: 755 IKEWQKEREILKKASQVLRVPPEKLPETAERFFNEWKEARKE----------VEKLKKEL 804
I + E+ K S+ + L A N+ K A + + L+K
Sbjct: 709 IAAYLNEQN--GKLSETINSLHNTLNNIANPALNKQKTALTKQLNHFHLPQVITDLRK-- 764
Query: 805 AKLLVYELEAKVQKVKEYEFIGEIVEGSMDDLREAVERLKKPNRIVVLVS 854
+ L+ EL+ V ++K +F + + + +++ + L K ++ VL S
Sbjct: 765 CQALLNELKITVNELKTEDFKWK-QKQLAEKIKQELLELAKQDKAYVLAS 813
>gb|AAF05590.1|AF188715_1 (AF188715) alanyl-tRNA synthetase [Caenorhabditis elegans]
Length = 793
Score = 137 bits (341), Expect = 6e-31
Identities = 188/787 (23%), Positives = 321/787 (39%), Gaps = 162/787 (20%)
Query: 61 EMREKFLKFFEKHEVYPHGRVKRYPVLPRWRDDVLL-VGASIMDFQPWVISG-EADPPAN 118
E+R+ F +FF+ H ++ V+P D LL A + F+P ++S E+ AN
Sbjct: 26 ELRKSFYEFFKSKN---HEILRSSSVIPDENDGTLLFTNAGMNQFKPLILSSTESRRVAN 82
Query: 119 PLVISQPSIRFTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFEFFTKEL 178
+ + D+D+VG H T FEMM + +FN + +E A+E+ + L
Sbjct: 83 IQKCIRAGGKHNDLDDVGKDLHHQTFFEMMGNWSFN----DAFSKEEACRYAWEYLVEIL 138
Query: 179 KMK-----------------PEDITFKE------------------NPWAGG--GNAGPA 201
+ PED +E N W G G GP
Sbjct: 139 GINADRLYVSYFGGIEKLGLPEDRECREIWKRIGVSSNRILPFVAENFWEMGAAGPCGPC 198
Query: 202 FEVLYR---GLEVATLVFMQYKKAPENAPEDQVVIIKGDRYVP-----------METKVV 247
E+ Y G + + LV + +D VV I ++ + +
Sbjct: 199 TEIHYDRIGGRDASRLVNI----------DDSVVEIWNIVFMSSVRDSCGQIRHLGKNHI 248
Query: 248 DTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSRLAGMFDIEDM 307
DTG G ERL+ + Q + +D V P+ +EK E + + G D
Sbjct: 249 DTGMGFERLLSVVQNKTSNFDTD---VFTPI-----LEKTSE---LAKKQYTGSLDSRQD 297
Query: 308 GDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSNVKAGYLA 367
+L +ADH +A T ++DG +P G++
Sbjct: 298 ATFRL----------------------------VADHIRAATVAISDGAVPDGTGCGFIV 329
Query: 368 RLLIRKS-IRHLKELGLE-VPLSEIVALHIKELHKTFPEFKEMEDVILEIIDLEEKKYSE 425
R ++R++ ++ + +LG+E +SE+V + + + +PE + I +I + EE ++ +
Sbjct: 330 RKMMRRAFLQGISKLGIERYAMSELVPVVASTMKEVYPEIHDTSTHIRKIFNDEEAQFWK 389
Query: 426 TLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKVHVPDNF 485
T+ + + A+ K +S K +E+HGL + E+A G +V +
Sbjct: 390 TVDKAKKMFDSVAAESKSPIISG---RKAFNLFETHGLPLAVTVELARNIGREVDETE-- 444
Query: 486 YSIVAKEAEKEKEEKEE-----EVVDFELVKDLPETRTLY----YEDPFMKEFEARVLRV 536
+ EA+K ++ + DF D + ++ YE P +K R+L+V
Sbjct: 445 FERCRLEAQKVSQKASQFKLPISADDFPSHSDKEKYSYVFRNGKYEFPQVK---TRILQV 501
Query: 537 IGD-------------WIVLDQTAFYPEGGGQPYDTGVLFVNGSEV-KVTNVQKVGKVIV 582
D ++VL++ FY E GGQ DTG L ++G EV +V N +K+ V
Sbjct: 502 YKDQQKAESLEANDRGFLVLEECQFYGEQGGQTSDTGHLLIDGREVFEVENAKKIAGGAV 561
Query: 583 HKVENPGL--FKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTT 640
+ L + + V ++D RR MR H+ TH+L AL + LG Q GS +
Sbjct: 562 TVLFGRALLPIRRDLRVEQKLDETRREGVMRAHSATHLLNWALQK-LGVGSGQKGSSVDC 620
Query: 641 DWARLDISHYKRISDEELREIER--LANRIVMEDRKVT----WEWLPRTEAEQRYGFRLY 694
D R D S DE+L + +R L + M+ R+ + + T E+
Sbjct: 621 DRFRFDYS----TGDEDLSKEQRTELLIKCEMKMREFIQNGGFTEIIETSLEEAKKIENL 676
Query: 695 QGGV----VPGRVIRVVKI---EDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERII 747
Q V + G +RVV + D V+ C GTH+ ++ + I+ + + + RII
Sbjct: 677 QSDVKEDRIGGASVRVVALGSGADVPVECCSGTHIHDVRVIDDVAIMSDKSMGQRLRRII 736
Query: 748 FACGEAA 754
G+ A
Sbjct: 737 VLTGKEA 743
>pir||C75511 alanyl-tRNA synthetase-related protein - Deinococcus radiodurans
(strain R1) >gi|6458192|gb|AAF10082.1|AE001909_4
(AE001909) alanyl-tRNA synthetase-related protein
[Deinococcus radiodurans]
Length = 409
Score = 136 bits (340), Expect = 8e-31
Identities = 117/403 (29%), Positives = 178/403 (44%), Gaps = 17/403 (4%)
Query: 514 PETRTLYYEDPFMKEFEARVLRVIGDWIVLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTN 573
P TR LY++ F A V+ V G + L TAFYPE GGQ D G+L GSE +VT+
Sbjct: 19 PMTRPLYHDPYQPLTFAASVVDVQGQEVALAATAFYPESGGQSSDVGLLRWPGSEARVTH 78
Query: 574 VQK--VGKVIVHKVENPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHV 631
+K + H+V+ L G EV G +D R +H + H+ H+L A RV
Sbjct: 79 ARKDKATGTVWHRVDGE-LPPVGAEVTGEVDPGPRWRHTQRHSAEHLLAQAFRRV--NPA 135
Query: 632 WQAGSQLTTDWARLDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQ-RYG 690
++ S T I + ++R E L + D ++T E EAE Y
Sbjct: 136 FEVASVNMTG-PECTIDFLGDPGEADIRAAEALLRETLGRD-ELTLETPIVPEAELVNYP 193
Query: 691 FRLYQ--GGVVPGRVIRVVKIEDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIF 748
R GG V + R + +DV ACGGTH+P + P+ ILRTER++ G R++F
Sbjct: 194 LRRESKVGGQVRLVMFRGSDGDFFDVSACGGTHVPGAAMCAPVVILRTERVRGGQVRVVF 253
Query: 749 ACGEAAIKEWQKEREILKKASQVLRVPPEKLPETAERFFNEWKEARKEVEKLKKELAKLL 808
GE A + + + +Q P +KLPE + AR + + L+ LA L
Sbjct: 254 MAGEEASEYLSGVYQSARTLAQEFSAPVDKLPERVAALRADLSAARADADALRARLAAQL 313
Query: 809 VYELEAKVQKVKEYEFIGEIVEGSMDDLREAVERLKKPNRIVVLVSKEGYFAISVGDNVN 868
V A+ + L V ++ V G ++ + +
Sbjct: 314 VAAASAEGTPPLRLLTLDNAA------LLAPVLTAVPAGEVLAAVGPGGRCGVASA-HPD 366
Query: 869 LNANDLAKKLTSIAGGGGGGRKDVAQGRIKDVSKAKEAIESIV 911
+ A D+ + ++ GG GGG+ D+AQG D EA+ ++
Sbjct: 367 VKAGDVLRAALAVTGGKGGGKPDLAQGSTADEGGFLEAVRQVL 409
>pir||B71231 alanine--tRNA ligase truncated homolog PH0108 - Pyrococcus
horikoshii >gi|3256494|dbj|BAA29177.1| (AP000001) 216aa
long hypothetical alanyl-tRNA synthetase [Pyrococcus
horikoshii]
Length = 216
Score = 135 bits (336), Expect = 2e-30
Identities = 89/232 (38%), Positives = 125/232 (53%), Gaps = 26/232 (11%)
Query: 516 TRTLYYEDPFMKEFEARVLRVIGDWIVLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTNVQ 575
TR LYYED ++KE + RVL + + I+LDQT FYP GGGQP+D G +NG EV
Sbjct: 5 TRKLYYEDAYLKEAKGRVLEIRDNAILLDQTIFYPTGGGQPHDRGT--INGVEVLDVYKD 62
Query: 576 KVGKVIVHKVENPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQ-A 634
+ G V H V+ P FK G EV +IDWD R + MR HTG H+L L VLG+ WQ
Sbjct: 63 EEGNV-WHVVKEPEKFKVGDEVELKIDWDYRYKLMRIHTGLHLLEHVLNEVLGEGNWQLV 121
Query: 635 GSQLTTDWARLDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFRLY 694
GS ++ + R DI++ + ++ + +I L N+ V E +V W E ++RY
Sbjct: 122 GSGMSVEKGRYDIAYPENLNKYK-EQIISLFNKYVDEGGEVKIWW----EGDRRY----- 171
Query: 695 QGGVVPGRVIRVVKIEDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERI 746
+I D++V CGGTH+ +G IK L+ I G +R+
Sbjct: 172 ------------TQIRDFEVIPCGGTHVKDIKEIGHIKKLKRSSIGRGKQRL 211
>pir||A75198 alanine--tRNA ligase truncated homolog PAB0066 - Pyrococcus abyssi
(strain Orsay) >gi|5457541|emb|CAB49032.1| (AJ248283)
fragment of ALANYL-TRNA SYNTHETASE [Pyrococcus abyssi]
Length = 213
Score = 133 bits (331), Expect = 1e-29
Identities = 87/232 (37%), Positives = 125/232 (53%), Gaps = 26/232 (11%)
Query: 516 TRTLYYEDPFMKEFEARVLRVIGDWIVLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTNVQ 575
TR LYYED ++KE +A+V+ + + ++LDQT FYP GGGQP+D G +NG EV
Sbjct: 2 TRKLYYEDAYLKEAKAKVVEIKDNALLLDQTIFYPTGGGQPHDRGT--INGVEVLDVYKD 59
Query: 576 KVGKVIVHKVENPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQ-A 634
+ G V H V+ P FK G EV +IDWD R + MR HTG H+L L VLG+ W+
Sbjct: 60 EEGNV-WHVVKEPEKFKVGDEVELKIDWDYRYKLMRIHTGLHLLEHVLNEVLGEGKWELV 118
Query: 635 GSQLTTDWARLDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFRLY 694
GS ++ + R DI++ + ++ + +I L N+ V E +V W E E RY
Sbjct: 119 GSGMSVEKGRYDIAYPENLNKYK-EQIISLFNKYVDEGGEVKIWW----EGETRY----- 168
Query: 695 QGGVVPGRVIRVVKIEDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERI 746
+I D++V CGGTH+ +G IK L+ I G +R+
Sbjct: 169 ------------TQIRDFEVIPCGGTHVKDIKEIGHIKKLKRSSIGRGKQRL 208
>dbj|BAB06653.1| (AP001517) unknown conserved protein in others [Bacillus
halodurans]
Length = 242
Score = 131 bits (327), Expect = 3e-29
Identities = 83/243 (34%), Positives = 127/243 (52%), Gaps = 6/243 (2%)
Query: 516 TRTLYYEDPFMKEFEARVLRVIGDWIVLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTNVQ 575
++ LY ED + +++ + V + D ++L++T F+P GGGQP D G L+ NG KV NV+
Sbjct: 2 SKELYLEDSYRQDYTSNVKLLNKDKVILEETIFHPNGGGQPNDEGWLYQNGKAYKVINVR 61
Query: 576 KVGKVIVHKVENPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAG 635
K G+ I+H +E+ +E EVR +I+W RR M++HT H++ G L G G
Sbjct: 62 KEGEEIIHYLEDADDLEED-EVRMKINWSRRYNFMKYHTLLHLVAGHLYHEYG--ALAIG 118
Query: 636 SQLTTDWARLDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFRLYQ 695
+Q+ + ARLDI D + +E NR++ E RK+ + R R
Sbjct: 119 NQIFENRARLDIDFRGGELDVDFHRVEEELNRLINEGRKMNIRNVERDSESISEKIRTVI 178
Query: 696 GGVVPGRV--IRVVKIEDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGEA 753
++P V IR+V IE+ D Q C GTH+ + +GP KI + G R+ F E
Sbjct: 179 -NLIPASVKNIRLVAIENMDEQPCSGTHVNNINEIGPFKISGNKSKGKGKRRLEFQLIEK 237
Query: 754 AIK 756
IK
Sbjct: 238 NIK 240
>gb|AAK40776.1| Alanyl-tRNA synthetase truncated homolog (alaS-like1) [Sulfolobus
solfataricus]
Length = 236
Score = 129 bits (322), Expect = 1e-28
Identities = 82/236 (34%), Positives = 128/236 (53%), Gaps = 8/236 (3%)
Query: 516 TRTLYYEDPFMKEFEARVLRVIGDWIVLDQTAFYPEGGGQPYDTGVLF-VNGSEVKVTNV 574
T LY +D ++KEFE RV+R+ G++++LD+TAFYP GGG DTG L G + VT V
Sbjct: 2 TEELYLKDSYIKEFEGRVVRIEGNYVILDKTAFYPGGGGLDNDTGFLVNEKGERISVTEV 61
Query: 575 QK-VGKVIVHKVENPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQ 633
++ I+HK++ G +V G IDWDRR + MR HT +H++ R G +
Sbjct: 62 KRGENGEILHKIDQNGSLNVNEKVIGTIDWDRRYRMMRLHTASHIVAALAYRKFGALI-- 119
Query: 634 AGSQLTTDWARLDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYGFRL 693
G ++ + A+ D + + + L E+ AN I+ +D ++ +LPR EA
Sbjct: 120 TGGHISPEQAKDDFNVENK---DTLIELINEANEIIKKDIELKIYFLPREEALMIPAIVK 176
Query: 694 YQGGVVPGRVI-RVVKIEDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIF 748
G P I R+V+I D+QA GG H+ +T +G I +L+ E G +R+ +
Sbjct: 177 LAGRNPPQIPIWRIVEIPGIDIQADGGPHVKNTKEIGEIVLLKVENKGKGRKRVYY 232
>pir||T26086 hypothetical protein W02B12.6 - Caenorhabditis elegans
>gi|3880430|emb|CAA91396.1| (Z66521) contains similarity
to Pfam domain: PF01411 (tRNA synthetases class II (A)),
Score=707.1, E-value=2.6e-209, N=2~cDNA EST yk50f6.3
comes from this gene~cDNA EST yk132c7.3 comes from this
gene~cDNA EST yk131c4.3 comes from this gene~cDNA EST
yk1>
Length = 835
Score = 127 bits (315), Expect = 7e-28
Identities = 189/824 (22%), Positives = 325/824 (38%), Gaps = 194/824 (23%)
Query: 61 EMREKFLKFFEKHEVYPHGRVKRYPVLPRWRDDVLL-VGASIMDFQPWVISG-EADPPAN 118
E+R+ F +FF+ H ++ V+P D LL A + F+P ++S E+ AN
Sbjct: 26 ELRKSFYEFFKSKN---HEILRSSSVIPDENDGTLLFTNAGMNQFKPLILSSTESRRVAN 82
Query: 119 PLVISQPSIRFTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFEFFTKEL 178
+ + D+D+VG H T FEMM + +FN + +E A+E+ + L
Sbjct: 83 IQKCIRAGGKHNDLDDVGKDLHHQTFFEMMGNWSFN----DAFSKEEACRYAWEYLVEIL 138
Query: 179 KMK-----------------PEDITFKE------------------NPWAGG--GNAGPA 201
+ PED +E N W G G GP
Sbjct: 139 GINADRLYVSYFGGIEKLGLPEDRECREIWKRIGVSSNRILPFVAENFWEMGAAGPCGPC 198
Query: 202 FEVLYR---GLEVATLVFMQYKKAPENAPEDQVVIIKGDRYVP-----------METKVV 247
E+ Y G + + LV + +D VV I ++ + +
Sbjct: 199 TEIHYDRIGGRDASRLVNI----------DDSVVEIWNIVFMSSVRDSCGQIRHLGKNHI 248
Query: 248 DTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSRLAGMFDIEDM 307
DTG G ERL+ + Q + +D V P+ +EK E + + G D
Sbjct: 249 DTGMGFERLLSVVQNKTSNFDTD---VFTPI-----LEKTSE---LAKKQYTGSLDSRQD 297
Query: 308 GDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSNVKAGYLA 367
+L +ADH +A T ++DG +P G++
Sbjct: 298 ATFRL----------------------------VADHIRAATVAISDGAVPDGTGCGFIV 329
Query: 368 RLLIRKS-IRHLKELGLE-VPLSEIVALHIKELHKTFPEFKEMEDVILEIIDLEEKKYSE 425
R ++R++ ++ + +LG+E +SE+V + + + +PE + I +I + EE ++ +
Sbjct: 330 RKMMRRAFLQGISKLGIERYAMSELVPVVASTMKEVYPEIHDTSTHIRKIFNDEEAQFWK 389
Query: 426 TLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKV------ 479
T+ + + A+ K +S K +E+HGL + E+A G +V
Sbjct: 390 TVDKAKKMFDSVAAESKSPIISG---RKAFNLFETHGLPLAVTVELARNIGREVDETEFE 446
Query: 480 ---------------------------HVPDNFYSIVAKEAEK-EKEEKEEEVVDFELV- 510
H YS V + + + E+K +++ F V
Sbjct: 447 RCRLEAQKVSQKASQFKLPISADDFPSHSDKEKYSYVFRNGKYGQLEQKSKKMRKFSSVF 506
Query: 511 KDLPETRTLYYEDPFMK-----------EFEARVLRVIGD-------------WIVLDQT 546
+ L +T + +K + + R+L+V D ++VL++
Sbjct: 507 RSLSFEKTKNHLHKMLKLITIISSNKFPQVKTRILQVYKDQQKAESLEANDRGFLVLEEC 566
Query: 547 AFYPEGGGQPYDTGVLFVNGSEV-KVTNVQKVGKVIVHKVENPGL--FKEGMEVRGRIDW 603
FY E GGQ DTG L ++G EV +V N +K+ V + L + + V ++D
Sbjct: 567 QFYGEQGGQTSDTGHLLIDGREVFEVENAKKIAGGAVTVLFGRALLPIRRDLRVEQKLDE 626
Query: 604 DRRIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTTDWARLDISHYKRISDEELREIER 663
RR MR H+ TH+L AL + LG Q GS + D R D S DE+L + +R
Sbjct: 627 TRREGVMRAHSATHLLNWALQK-LGVGSGQKGSSVDCDRFRFDYS----TGDEDLSKEQR 681
Query: 664 --LANRIVMEDRKVT----WEWLPRTEAEQRYGFRLYQGGV----VPGRVIRVVKI---E 710
L + M+ R+ + + T E+ Q V + G +RVV +
Sbjct: 682 TELLIKCEMKMREFIQNGGFTEIIETSLEEAKKIENLQSDVKEDRIGGASVRVVALGSGA 741
Query: 711 DWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGEAA 754
D V+ C GTH+ ++ + I+ + + + RII G+ A
Sbjct: 742 DVPVECCSGTHIHDVRVIDDVAIMSDKSMGQRLRRIIVLTGKEA 785
>emb|CAA83717.1| (Z33042) Ala-tRNA synthetase [Mycoplasma capricolum]
Length = 411
Score = 123 bits (305), Expect = 1e-26
Identities = 123/466 (26%), Positives = 196/466 (41%), Gaps = 116/466 (24%)
Query: 55 KKYTLDEMREKFLKFFEKHEVYPHGRVKRYPVLPRWRDD--VLLVGASIMDFQPWVISGE 112
KK + +++R+ +L FF Y V PV DD +L + + + +P+ G
Sbjct: 2 KKLSTNQIRKIWLDFFISKNHYFLEPVSLIPV-----DDPSLLWINSGVATLKPY-FDGR 55
Query: 113 ADPPANPLVISQPSIRFTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFE 172
PP+ L SQ +IR DI+NVG+T RH T+FEM+ + + Y+ E +ELA+E
Sbjct: 56 KTPPSPRLTNSQKAIRTNDIENVGVTARHHTMFEMLGNFSIGD-----YFKKEAIELAWE 110
Query: 173 FFT---------------------------KELKMKPEDITF----KENPW-AGGGNAGP 200
T K++ ED F K N W G G GP
Sbjct: 111 LLTDKNYFDIDKNKLYITVFNEDIEAYNIWKDVIKIDEDHIFRLSKKTNFWDVGQGPCGP 170
Query: 201 AFEVLY-----------------------RGLEVATLVFMQYKKAPENAPEDQVVIIKGD 237
E+ Y R +EV +VF Q+ N
Sbjct: 171 NTEIFYDRGEIWDPNKIGPRLISDDIENDRYIEVWNIVFSQFNNDGNN------------ 218
Query: 238 RYVPMETKVVDTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSR 297
YV + K +DTG GLER + Q TPT ++ + Y ++K+++ + N++
Sbjct: 219 NYVELPRKNIDTGAGLERFASIFQNTPTNFETDIFYPT--------IKKVEQ---LTNNQ 267
Query: 298 LAGMFDIEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVI 357
D + K R A KV IADH +A F ++DGV
Sbjct: 268 FKYSIDNYFNPNKKQTRINTAFKV-------------------IADHIRATVFAISDGVF 308
Query: 358 PSNVKAGYLARLLIRKSIRHLKELGL-EVPLSEIVALHIKELHKTFPEFKEMEDVILEII 416
P N GY+ R LIR+S ELG+ + L ++V I+ + + +P + + ++ + I
Sbjct: 309 PGNKDRGYIIRRLIRRSCVFGNELGIKQAFLYKLVDSVIESMKEFYPYLVDKKSLVEQTI 368
Query: 417 DLEEKKYSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHG 462
EE+K+ +TL +G DL+ I K + + + + +ES+G
Sbjct: 369 KDEEEKFLKTLSKGYDLLENII-----KTKNTVSDKDALLLFESYG 409
>pir||S77844 alanine--tRNA ligase (EC 6.1.1.7) - Mycoplasma capricolum
(fragment)
Length = 410
Score = 123 bits (305), Expect = 1e-26
Identities = 123/466 (26%), Positives = 196/466 (41%), Gaps = 116/466 (24%)
Query: 55 KKYTLDEMREKFLKFFEKHEVYPHGRVKRYPVLPRWRDD--VLLVGASIMDFQPWVISGE 112
KK + +++R+ +L FF Y V PV DD +L + + + +P+ G
Sbjct: 2 KKLSTNQIRKIWLDFFISKNHYFLEPVSLIPV-----DDPSLLWINSGVATLKPY-FDGR 55
Query: 113 ADPPANPLVISQPSIRFTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFE 172
PP+ L SQ +IR DI+NVG+T RH T+FEM+ + + Y+ E +ELA+E
Sbjct: 56 KTPPSPRLTNSQKAIRTNDIENVGVTARHHTMFEMLGNFSIGD-----YFKKEAIELAWE 110
Query: 173 FFT---------------------------KELKMKPEDITF----KENPW-AGGGNAGP 200
T K++ ED F K N W G G GP
Sbjct: 111 LLTDKNYFDIDKNKLYITVFNEDIEAYNIWKDVIKIDEDHIFRLSKKTNFWDVGQGPCGP 170
Query: 201 AFEVLY-----------------------RGLEVATLVFMQYKKAPENAPEDQVVIIKGD 237
E+ Y R +EV +VF Q+ N
Sbjct: 171 NTEIFYDRGEIWDPNKIGPRLISDDIENDRYIEVWNIVFSQFNNDGNN------------ 218
Query: 238 RYVPMETKVVDTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSR 297
YV + K +DTG GLER + Q TPT ++ + Y ++K+++ + N++
Sbjct: 219 NYVELPRKNIDTGAGLERFASIFQNTPTNFETDIFYPT--------IKKVEQ---LTNNQ 267
Query: 298 LAGMFDIEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVI 357
D + K R A KV IADH +A F ++DGV
Sbjct: 268 FKYSIDNYFNPNKKQTRINTAFKV-------------------IADHIRATVFAISDGVF 308
Query: 358 PSNVKAGYLARLLIRKSIRHLKELGL-EVPLSEIVALHIKELHKTFPEFKEMEDVILEII 416
P N GY+ R LIR+S ELG+ + L ++V I+ + + +P + + ++ + I
Sbjct: 309 PGNKDRGYIIRRLIRRSCVFGNELGIKQAFLYKLVDSVIESMKEFYPYLVDKKSLVEQTI 368
Query: 417 DLEEKKYSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHG 462
EE+K+ +TL +G DL+ I K + + + + +ES+G
Sbjct: 369 KDEEEKFLKTLSKGYDLLENII-----KTKNTVSDKDALLLFESYG 409
>sp|O83980|SYA_TREPA ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|7514240|pir||E71253 alanine--tRNA ligase (EC
6.1.1.7) (alaS) - syphilis spirochete
>gi|3323345|gb|AAC65968.1| (AE001269) alanyl-tRNA
synthetase (alaS) [Treponema pallidum]
Length = 605
Score = 121 bits (300), Expect = 4e-26
Identities = 122/480 (25%), Positives = 196/480 (40%), Gaps = 123/480 (25%)
Query: 60 DEMREKFLKFFEKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPANP 119
D++R ++L FF + H + ++P VL A + P+++ GE P
Sbjct: 8 DQLRSRYLAFFSQKA---HVVISGKSLVPEHDPTVLFTTAGMHPLVPYLM-GEPHPAGTR 63
Query: 120 LVISQPSIRFTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFEFFTKE-- 177
LV +Q +R DID VG H T FEM+ + + Y+ +E + +FEF T
Sbjct: 64 LVNAQKCLRTGDIDAVG-DNSHLTFFEMLGNWSLGD-----YFKEEAIAFSFEFLTGAPW 117
Query: 178 LKMKPEDITFK----------------------------------ENPWAGGGNAGPA-- 201
L + P+ ++ +N W G GP
Sbjct: 118 LGISPDRLSVTVFAGDEAVARDEESAAIWERLGIARTHIHFLPRADNWWGPTGETGPCGP 177
Query: 202 -FEVLY------------------RGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYVPM 242
E+ + + +E+ VFMQY+K + RY P+
Sbjct: 178 DTEIFFDTGVPPCSVSCRPGCSCGKYVEIWNDVFMQYRKDADG------------RYRPL 225
Query: 243 ETKVVDTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSRLAGMF 302
E VDTG G+ER V + QG + YD + PL G +L G
Sbjct: 226 ERYCVDTGMGIERTVAVLQGKRSVYDTE---IFTPLLERIG-------------QLCG-- 267
Query: 303 DIEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVI--PSN 360
K + A V + + + DH +A TF+L D V PSN
Sbjct: 268 --------KRYGCQGAHDVSMRI---------------VCDHIRAATFILGDPVPVRPSN 304
Query: 361 VKAGYLARLLIRKSIRHLKELGLEVP-LSEIVALHIKELHKTFPEFKEMEDVILEIIDLE 419
V AGY+ R +IR+S+RH ++LG++ LS + + I + +PE +E I + + E
Sbjct: 305 VGAGYVLRRIIRRSVRHGRKLGIDGEFLSSLARVVIGQYAAVYPELEEKATCIAQELANE 364
Query: 420 EKKYSETLKRGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKV 479
E+K+ + L++G R I K + EIP Y+++G EL +E+A + G++V
Sbjct: 365 ERKFLDALRKGEAEYERMIPKFLQGTEREIPGSVAFRLYDTYGFPLELTEELARESGLRV 424
Score = 74.1 bits (179), Expect = 6e-12
Identities = 46/143 (32%), Positives = 69/143 (48%), Gaps = 2/143 (1%)
Query: 604 DRRIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTTDWARLDISHYKRISDEELREIER 663
D + +HT TH+L AL VLG HV Q GS +T + R D SH + +S +E ++E+
Sbjct: 454 DHSAETTAYHTATHLLHQALRVVLGTHVQQKGSNITAERLRFDFSHPRPMSAQEKVQVEQ 513
Query: 664 LANRIVMEDRKVTWEWLPRTEAEQRYGFRLYQGGVVPGRVIRVVKIEDWDVQACGGTHLP 723
L N + D V E + +A L+ G ++V I + + CGG H+
Sbjct: 514 LVNEQIRADLPVCCEVMSLEDAMNSGAVALF--GEKYESTVKVYSIGTFSREVCGGPHVA 571
Query: 724 STGLVGPIKILRTERIQDGVERI 746
TG +G I + + GV RI
Sbjct: 572 RTGQLGRFSIQKEQSSAAGVRRI 594
>pir||G72685 probable alanyl-tRNA synthetase APE0903 - Aeropyrum pernix (strain
K1) >gi|5104572|dbj|BAA79887.1| (AP000060) 274aa long
hypothetical alanyl-tRNA synthetase [Aeropyrum pernix]
Length = 274
Score = 119 bits (296), Expect = 1e-25
Identities = 82/247 (33%), Positives = 126/247 (50%), Gaps = 15/247 (6%)
Query: 515 ETRTLYYEDPFMKEFEARVLRVIGDWIVLDQTAFYP-EGGGQPYDTGVLFVNGSEVKVTN 573
+T LY +D +++EFEARV G +VLD+TAF+P GG DTG +F +V
Sbjct: 27 KTVLLYQQDSYLREFEARVEEASGGRVVLDRTAFHPGPHGGLDTDTGYIFYGDKRYRVVR 86
Query: 574 VQKVGKVIVHKVE-NPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKH-V 631
G V+ H ++ + + G V+G IDW+RR + MR HT +H+L L KH V
Sbjct: 87 AAVEGDVVAHYLDSDTATLEPGAVVKGVIDWERRYRMMRLHTFSHILAAVLYE---KHDV 143
Query: 632 WQAGSQLTTDWARLDIS----HYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQ 687
G +T D+ + D S ++ + +E RE +A+R + +V WLPR EA +
Sbjct: 144 LVTGGHITPDYGKDDFSIEGGGWREVIEEAFREANEIASRCI----EVKVYWLPREEALK 199
Query: 688 RYGFRLYQGGVVPG-RVIRVVKIEDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERI 746
G + P +R+V+I DVQA GG H+ +T +G + I + E +R+
Sbjct: 200 IPGIVKLANKLPPEVETLRIVEIPGVDVQADGGPHVRNTCEIGRVVITKLESKGKRRKRV 259
Query: 747 IFACGEA 753
+ EA
Sbjct: 260 YYTLEEA 266
>pir||E72216 alanine--tRNA ligase truncated homolog TM1726 - Thermotoga maritima
(strain MSB8) >gi|4982303|gb|AAD36791.1|AE001812_1
(AE001812) alanyl-tRNA synthetase-related protein
[Thermotoga maritima]
Length = 373
Score = 117 bits (291), Expect = 5e-25
Identities = 96/314 (30%), Positives = 163/314 (51%), Gaps = 25/314 (7%)
Query: 548 FYPEG-GGQPYDTGVLFVNGSEVKVTNVQKVGKVIVHKVENPGLFKEGMEVRGRIDWDRR 606
FYP+G GGQ D G + V V++ I+H ++ E + ID RR
Sbjct: 27 FYPDGKGGQLGDRGKI----GPANVLKVKEKNGYILHYLD---AHLEPGDYECEIDPARR 79
Query: 607 IQHMRHHTGTHVLMGALVRVLGKHV--WQAGSQLTTDWARLDISHYKRISDEELREIERL 664
HT H+L A ++V + G +++T +D++ + ++ L E E L
Sbjct: 80 KDIACQHTAQHILSAAFLKVADLETVSFHMGERVST----IDLNA-PFVLEDVLEEAEDL 134
Query: 665 ANRIVMEDRKVTWEWLPRTEAEQRYGFRLYQGGVVPGRVIRVVKIEDWDVQACGGTHLPS 724
AN +V +V + + EAE+ L + V G+V RVVKI D+DV ACGG H+ +
Sbjct: 135 ANEVVRSCERVEILEIEKEEAEK---MNLRKLPNVEGKV-RVVKIGDFDVTACGGFHVEN 190
Query: 725 TGLVGPIKILRTERIQDGVERIIFACGEAAIKEWQKEREILKKASQVLRVPPEKLPETAE 784
TG +G IKI+ TE+++ + RI F G+ A+K+++++ ++LK S+VL ++L + AE
Sbjct: 191 TGEIGLIKIVDTEKVKKVLTRIYFTAGDRALKDYREKDKLLKSLSRVLTTSTKELLKRAE 250
Query: 785 RFFNEWKEARKEVEKLKKELAKLLVYELE-AKVQKVKEYEFIG-----EIVEGSMDDLRE 838
E KE +++KL ++ A++L E KV K Y F G + + + D ++
Sbjct: 251 NLLEEVKEKSAKLDKLSEKYAEILSKVAEPEKVGKYYLYHFSGTPEEMKYLPKFLADRKD 310
Query: 839 AVERLKKPNRIVVL 852
+ L+ P+RI ++
Sbjct: 311 TIVLLEHPDRIEIV 324
>sp|O51238|SYA_BORBU ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|7463022|pir||D70127 alanine--tRNA ligase (EC
6.1.1.7) alaS - Lyme disease spirochete
>gi|2688110|gb|AAC66604.1| (AE001132) alanyl-tRNA
synthetase (alaS) [Borrelia burgdorferi]
Length = 594
Score = 106 bits (263), Expect = 9e-22
Identities = 119/483 (24%), Positives = 195/483 (39%), Gaps = 128/483 (26%)
Query: 58 TLDEMREKFLKFFEKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEADPPA 117
TL+++R+K++ FF+ + H + ++P VL A + P+++ GE P
Sbjct: 2 TLNKLRKKYIDFFKSKK---HFEIMGKSLVPENDPTVLFNTAGMQPLIPYLL-GEVHPSG 57
Query: 118 NPLVISQPSIRFTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFEFFTKE 177
+ LV Q +R DID VG H T FEM+ + + Y+ + +V+ +FEF T
Sbjct: 58 DMLVNVQKCLRTGDIDEVGDLS-HLTFFEMLGNWSLG-----AYFKEYSVKCSFEFLTSS 111
Query: 178 LKMK-PEDITFKE--------------------------------------NPWAGGGNA 198
+ P+D + P G
Sbjct: 112 DYLNIPKDSLYVSVFEGDQEIPRDTETAKVWESLGISKDRIHYLSKDHNFWGPVGSKGPC 171
Query: 199 GPAFEVLY------------------RGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYV 240
GP E+ + E+ VFMQY K EN Y+
Sbjct: 172 GPDTEIYVDTGKSKCSLDCNITCSCGKYFEIWNNVFMQYNK-DENG-----------NYI 219
Query: 241 PMETKVVDTGYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSRLAG 300
+ K VDTG GLER + QG + YD I +RI + ++ G
Sbjct: 220 ELGRKCVDTGMGLERTIAFLQGKSSVYDT------------DAFMPIIKRIEYISGKIYG 267
Query: 301 MFDIEDMGDLKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADG--VIP 358
+ +D I I+DH KA F+LAD V P
Sbjct: 268 QKEDDD-----------------------------RCIRIISDHVKAACFILADSSVVFP 298
Query: 359 SNVKAGYLARLLIRKSIRHLKELGLEVPLSEIVALHIKELHKTF-PEFKEMEDVILEIID 417
SN+ GY+ R LIR+SIR+ K+LG++ + ++ ++++F E E +D I + +
Sbjct: 299 SNLGQGYVLRRLIRRSIRYAKKLGIKSHFLADLVDSVEAIYRSFYNELTEKKDFIKKELS 358
Query: 418 LEEKKYSETLKRGSDLVRREIAKLKKKGMSE-IPLEKLITFYESHGLTPELVKEIAEKEG 476
EE+K+ +TL +G +E K+ + S+ IP + Y+++G E+ +E+A + G
Sbjct: 359 KEEEKFFKTLSQG----EQEFIKITRNLPSKTIPGDIAFKLYDTYGFPYEVTEELAIEYG 414
Query: 477 IKV 479
V
Sbjct: 415 FNV 417
Score = 79.2 bits (192), Expect = 2e-13
Identities = 41/134 (30%), Positives = 73/134 (53%), Gaps = 2/134 (1%)
Query: 613 HTGTHVLMGALVRVLGKHVWQAGSQLTTDWARLDISHYKRISDEELREIERLANRIVMED 672
HT TH+L AL VLG HV Q GS +T + R D H ++++D+E++++E + N +
Sbjct: 456 HTATHLLHKALQLVLGDHVRQKGSNITAERLRFDFVHSEKMTDDEIKKVEEIVNLQIKNS 515
Query: 673 RKVTWEWLPRTEAEQRYGFRLYQGGVVPGRVIRVVKIEDWDVQACGGTHLPSTGLVGPIK 732
V + +EA ++ L+ G ++ V +I+ + ++ CGG H+ +T +G K
Sbjct: 516 LSVKKIIMELSEAREKGAMALF--GEKYDDLVSVYEIDGFSLEVCGGPHVENTNELGTFK 573
Query: 733 ILRTERIQDGVERI 746
I + + G+ RI
Sbjct: 574 IQKEQSSSSGIRRI 587
>gb|AAF45874.1| (AE003427) CG10802 gene product [Drosophila melanogaster]
Length = 297
Score = 104 bits (258), Expect = 3e-21
Identities = 83/260 (31%), Positives = 123/260 (46%), Gaps = 32/260 (12%)
Query: 522 EDPFMKEFEARVLR---VIGDW--------------IVLDQTAFYPEGGGQPYDTGVLFV 564
ED F+KEF+ +++ DW ++ + T +PEGGGQP D G L
Sbjct: 7 EDSFLKEFKTKIVSSEFATLDWTDPSGKVEKLKGFNVICEDTILFPEGGGQPCDYGTL-- 64
Query: 565 NGSEVKVTNVQKVGKVIVHKVENPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALV 624
G VK NVQ+ G VH VE+P F++ EV +D+ RR+ HM+ H+G H++
Sbjct: 65 GGFPVK--NVQRKGSTAVHFVESPTSFEQDAEVLLTLDYQRRLDHMQQHSGQHLITALFD 122
Query: 625 RVLGKHV--WQAGSQLTTDWARLDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPR 682
R W GS T + +L H IS E L IER AN ++ E R+VT +
Sbjct: 123 REFKYDTTSWSLGS--TVSYIQLSTPHL--ISRESLDLIERQANDLIREGREVTVLLVDP 178
Query: 683 TEAEQRYGFRLYQGGVVP---GRVIRVVKIEDWDVQACGGTHLPSTGLVGPIKILRTERI 739
A++ R +G +P + RVV+IE + C GTH+ + + IK+L E
Sbjct: 179 EVAQEFQDARAPRG--LPKDHEGLARVVRIEGIESNMCCGTHVTNLSQLQCIKLLYAEEG 236
Query: 740 QDGVERIIFACGEAAIKEWQ 759
+ + E A K W+
Sbjct: 237 EGECSGALCRRREGARKAWR 256
>pir||A83382 hypothetical protein PA2106 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9948120|gb|AAG05494.1|AE004638_4
(AE004638) hypothetical protein [Pseudomonas aeruginosa]
Length = 244
Score = 102 bits (251), Expect = 2e-20
Identities = 72/253 (28%), Positives = 121/253 (47%), Gaps = 23/253 (9%)
Query: 513 LPETRTLYYEDPFMKEFEARVLRVIGDWIVLDQTAFYPEGGGQPYDTGVL-FVNGSEVKV 571
+ +T +L+ +D + +E AR+ V+ D ++LDQT FYP+GGGQ D+G L +G+ +++
Sbjct: 1 MTQTASLFLQDSYREECLARITDVVEDGLLLDQTVFYPQGGGQAGDSGWLTLADGTRLRI 60
Query: 572 TNVQK-----VGKVIVHKVENPG------LFKEGMEVRGRIDWDRRIQHMRHHTGTHVLM 620
+ +K G+ + + G K G V +IDW RR +HMR HT H+L
Sbjct: 61 ADTRKGTEAGAGRDAILHIPAEGQATVLRAMKPGEVVLAQIDWVRRYRHMRLHTAAHMLC 120
Query: 621 GALVRVLGKHVWQAGSQLTTDWARLDISHYKRISDEELREIERLANRIVMEDRKVTWEWL 680
L + G +T + ARLD + +S E I+ +V V+ + +
Sbjct: 121 AVLPYPVN------GCSITDEHARLDFVTSEPLSRE---AIDSALAAMVEAAHPVSIDTM 171
Query: 681 PRTEAEQRYGFRLYQGGVVP--GRVIRVVKIEDWDVQACGGTHLPSTGLVGPIKILRTER 738
R P +R+V I+D D+Q CGGTH+ +T VG +++ + E+
Sbjct: 172 SDDALRARPDLVRTMSVQPPMGAGQVRLVSIKDTDLQPCGGTHVANTEEVGVVRVSKMEK 231
Query: 739 IQDGVERIIFACG 751
R++ G
Sbjct: 232 KSARTRRVVLVLG 244
>sp|Q56648|SYA_VIBCH ALANYL-TRNA SYNTHETASE (ALANINE--TRNA LIGASE) (ALARS)
>gi|1321619|gb|AAA99922.1| (L78074) alanyl-tRNA
synthetase [Vibrio cholerae]
Length = 409
Score = 96.7 bits (237), Expect = 1e-18
Identities = 90/411 (21%), Positives = 166/411 (39%), Gaps = 124/411 (30%)
Query: 128 RFTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFEFFTKELKMKPE---- 183
+ D++NVG T RH T FEM+ + +F Y+ ++ ++ A+EF T L++ E
Sbjct: 31 KHNDLENVGFTARHHTFFEMLGNFSFGD-----YFKEDAIQYAWEFLTDVLQLPKERLLV 85
Query: 184 ----------DITFK-----------------------ENPWAGG--GNAGPAFEVLY-- 206
DI K +N W G G GP E+ Y
Sbjct: 86 TVYETDDEAFDIWNKKVGIPADRIIRIGDKKGGKKFDSDNFWQMGDTGPCGPCTEIFYDH 145
Query: 207 -----------------RGLEVATLVFMQYKKAPENAPEDQVVIIKGDRYVPMETKVVDT 249
R +E+ VFMQ+ + + E P+ VDT
Sbjct: 146 GDHIWGGPPGSPEEDGDRFIEIWNNVFMQFNRHADGTME------------PLPKPSVDT 193
Query: 250 GYGLERLVWMSQGTPTAYDAVLGYVVEPLKRMAGVEKIDERILMENSRLAGMFDIEDMGD 309
G G+ER+ + QG + Y+ D+
Sbjct: 194 GMGIERISAIMQGVHSNYE---------------------------------IDV----- 215
Query: 310 LKLLRKKVAEKVGISVEELEKAIRPYELIYAIADHTKALTFMLADGVIPSNVKAGYLARL 369
+ L K A+ +G + +++R +ADH ++ F++ DGV+PSN GY+ R
Sbjct: 216 FQTLIKAAADAIGYQ-DLTNQSLR------VVADHIRSCAFLIVDGVMPSNEGRGYVLRR 268
Query: 370 LIRKSIRHLKELGLEVPLSEIVALHIKELHKTF-PEFKEMEDVILEIIDLEEKKYSETLK 428
+IR+++RH +LG + + + E+ T E K+ + ++ +++ +EE+ + TL
Sbjct: 269 IIRRAVRHGNKLGAQGAFFHKLVGPLAEVMGTAGVELKKQQALVEKVLRIEEENFGRTLD 328
Query: 429 RGSDLVRREIAKLKKKGMSEIPLEKLITFYESHGLTPELVKEIAEKEGIKV 479
RG ++ + +L + + E + Y+++G +L ++A + G +
Sbjct: 329 RGMSILNDALDQLSGQVLDG---ETVFKLYDTYGFPADLTNDVARERGFSI 376
>pir||B71172 alanine--tRNA ligase truncated homolog PH0574 - Pyrococcus
horikoshii >gi|3256980|dbj|BAA29663.1| (AP000002) 157aa
long hypothetical alanyl-tRNA synthetase [Pyrococcus
horikoshii]
Length = 157
Score = 96.0 bits (235), Expect = 2e-18
Identities = 54/127 (42%), Positives = 77/127 (60%), Gaps = 3/127 (2%)
Query: 610 MRHHTGTHVLMGALVRVLGKHV-WQAGSQLTTDWARLDISHYKRISDEELREIERLANRI 668
+R H+ HV+ GA+V+VLG W + + + L + ++ SDEE+REIERLAN
Sbjct: 6 VRTHSALHVVKGAVVKVLGSEAKWTYSTYVKGNKGVLIVKFDRKPSDEEIREIERLANEK 65
Query: 669 VMEDRKVTWEWLPRTEAEQRYGFRLYQGGVVPG--RVIRVVKIEDWDVQACGGTHLPSTG 726
V E+ + LPR EAE+ +G +Y VP R+++VV IEDW+V AC H +TG
Sbjct: 66 VKENAPIKIYELPREEAEKMFGEDMYDLFPVPEDVRILKVVVIEDWNVNACNKEHTKTTG 125
Query: 727 LVGPIKI 733
+GPIKI
Sbjct: 126 EIGPIKI 132
>gb|AAF05591.1|AF188716_1 (AF188716) alanyl-tRNA synthetase [Drosophila melanogaster]
Length = 1012
Score = 90.5 bits (221), Expect = 8e-17
Identities = 113/501 (22%), Positives = 211/501 (41%), Gaps = 90/501 (17%)
Query: 341 IADHTKALTFMLADGVIPSNVKAGYLARLLIRKSIRHLKEL-GLEVPLSEIVALHIKELH 399
+ADH + +T LADG++P + R ++RK++ + + + L+++V + ++ L
Sbjct: 306 LADHARMVTACLADGMLPDQNQK---LRRVLRKALNISEHVFAHDKLLTQLVPIVVETLG 362
Query: 400 KTFPEFKEMEDVILEIIDLEEKKYSETLKRGS----------------DLVR-------- 435
+ +PE + ++++I E++ Y + S DL+
Sbjct: 363 EAYPEMAAKQQAVIDLICHEQEVYKNLRESSSKAFAEVLMEFPNLDDIDLMECPGFVPAY 422
Query: 436 REIAKLKKK-GMSEIPLEKLITFYESHGLTPELVKEIAEKEGI-----KVHVPDNFYSIV 489
RE+ + K + IP + L +++GLT E ++AE E + + N +
Sbjct: 423 RELQMQRCKFSNNTIPGDFLYKLTDTYGLTEESFLKLAELENMNCDLERYRAEVNLAKLK 482
Query: 490 AKEAEKEKE-------EKEEEVVDFE--LVKDLPETRTLY-YEDPFMKEFEARVL----- 534
AK ++E E+ + + + L K L T + Y F KE ++ +
Sbjct: 483 AKGNQRETAGGSLCDLATEQRIAEAQAMLTKRLTPTDNSHKYTYSFDKESDSYQIPPLKT 542
Query: 535 RVIGDW-----------------------IVLDQTAFYPEGGGQPYDTGVLFVNGSE--- 568
RV+G IV + FY E GGQ D G + V+ +
Sbjct: 543 RVLGMLLNDAEVSRTQGSRIQQPFTDLISIVTAGSNFYYESGGQQSDGGKILVSNHQQPD 602
Query: 569 ----VKVTNVQKVGKVIVH--KVENPG---LFKEGMEVRGRIDWDRRIQHMRHHTGTHVL 619
+ V V+ + +VH K+ +P G EV ++D +R + HHT TH+L
Sbjct: 603 HPHSLDVIGVKHLNDCVVHICKLSSPTDAFQLAIGDEVELQVDAQQRQLNTCHHTATHLL 662
Query: 620 MGALVRVLGKHVWQAGSQLTTDWARLDISHY-KRISDEELREIERLANRIVMEDRKVTWE 678
A+ + K +Q S +++D +L++ KRI +++ IE L NR++ V +
Sbjct: 663 NAAIRSLFKKVTYQVSSSVSSDQCKLELGLLGKRIQKTDVQLIEDLINRVICSAAPVEVQ 722
Query: 679 WLPRTEAEQRYGFRLYQGGVVPGRVIRVVKIEDWDVQ-----ACGGTHLPSTGLVGPIKI 733
L E ++ + G V P + +R+V +E ++Q C GTH +T + I
Sbjct: 723 LLSAAEVLEQNDITMVPGEVYPEQGLRLVNVESPELQLSSKELCCGTHATNTSELSCFCI 782
Query: 734 LRTERIQDGVERIIFACGEAA 754
+ ++ G+AA
Sbjct: 783 VNLKQTNRARFAFTAVAGQAA 803
>gi|6324288 Ynl040wp [Saccharomyces cerevisiae]
>gi|1730724|sp|P53960|YNE0_YEAST HYPOTHETICAL 51.0 KD
PROTEIN IN YIP3-TFC5 INTERGENIC REGION
>gi|2131872|pir||S62962 hypothetical protein YNL040w -
yeast (Saccharomyces cerevisiae)
>gi|1301892|emb|CAA95907.1| (Z71316) ORF YNL040w
[Saccharomyces cerevisiae]
Length = 456
Score = 90.5 bits (221), Expect = 8e-17
Identities = 97/405 (23%), Positives = 168/405 (40%), Gaps = 47/405 (11%)
Query: 541 IVLDQTAFYPEGGGQPYDTGVL-FVNGSEVKVTNVQKVGKVIVHKVENPGL--------- 590
I L T +PEGGGQP D+G L V G+ N K+ K++V V GL
Sbjct: 47 IELQDTILFPEGGGQPSDSGFLKIVEGNR----NSSKIEKILVSHVSRFGLHAKHHVNDY 102
Query: 591 FKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVR--VLGKHVWQAGSQLTTDWARLDIS 648
+ G V +D +R+ +M+ HTG H+L L R + W G +T L+ S
Sbjct: 103 IEPGTTVEVAVDEQKRMDYMQQHTGQHLLSAILERNYKVDTVSWSMGGIITKKKPVLEPS 162
Query: 649 HY-------KRISDEELREIERLANRIVME--DRKVTWEWLPRTEAEQRYGFRLYQGGVV 699
Y ++++ +E+ + N++++ + E + ++ ++ +
Sbjct: 163 DYFNYIELNRKLTLDEITNVSDEINQLIINFPQEIIVEERIGEETVDEVSTSKIPDDYDL 222
Query: 700 PGRVIRVVKIEDWDVQACGGTHLPSTGLVGPIKILRTE-RIQDGVERIIFACGEAAIKEW 758
V+R + I D D C GTHL T +G I IL + ++ R+ F CG+
Sbjct: 223 SKGVLRTIHIGDIDSNPCCGTHLKCTSQIGSILILSNQSAVRGSNSRLYFMCGKRVSLYA 282
Query: 759 QKEREILKKASQVLRVPPEKLPETAERFFNEWKEARKEVEKLKKELAKLLVYELEAKVQ- 817
+ +IL + +L ++ E R + ++ K + K LA+ EL ++
Sbjct: 283 KSVNKILLDSKNLLSCSETQISEKITRQTKQIQQLNKREQYWIKRLARTASEELMNTLKA 342
Query: 818 KVKEYEFIGEIVEGSMDDLREAVERLKKPNRIVVLVSKEGYFAISVGDNVNLNANDL--- 874
K+ + E G++ E + ++ K + EGY I G N L
Sbjct: 343 SGKKRAYFMEEEYGTL----ELLLQIHKEVSNFLKDDTEGYEIILCGYERQTNTGSLLIL 398
Query: 875 ---AKKLTSIAG----------GGGGGRKDVAQGRIKDVSKAKEA 906
+K+ ++A GGGG + QG+I +S A+ A
Sbjct: 399 SESGEKIANLAANLGSILQNLKGGGGKKGGKWQGKITSISNAEFA 443
>pir||A75053 alanine--tRNA ligase truncated homolog PAB1440 - Pyrococcus abyssi
(strain Orsay) >gi|5458831|emb|CAB50318.1| (AJ248287)
ALANYL-TRNA SYNTHETASE fragment [Pyrococcus abyssi]
Length = 159
Score = 89.7 bits (219), Expect = 1e-16
Identities = 50/127 (39%), Positives = 76/127 (59%), Gaps = 3/127 (2%)
Query: 610 MRHHTGTHVLMGALVRVLGKHV-WQAGSQLTTDWARLDISHYKRISDEELREIERLANRI 668
+R H+ HV+ GA+V+VLG+ W + + + L + ++ S+EE+R IE LAN
Sbjct: 8 VRTHSALHVVKGAVVKVLGERAKWTYSTYVKGNRGVLTVKFDRKPSEEEIRRIEELANEK 67
Query: 669 VMEDRKVTWEWLPRTEAEQRYGFRLYQGGVVPG--RVIRVVKIEDWDVQACGGTHLPSTG 726
V E+ + LPR EAE+R+G +Y VP ++++VV IEDW+V AC H+ TG
Sbjct: 68 VRENIPIKVYELPREEAEKRFGEEMYDLFPVPEDVKILKVVVIEDWNVNACNKEHVKRTG 127
Query: 727 LVGPIKI 733
+G IKI
Sbjct: 128 EIGKIKI 134
>emb|CAC00447.1| (AL160371) possible hypothetical 51.0 Kd protein in yip3-tfc5
intergenic region [Leishmania major]
Length = 546
Score = 89.7 bits (219), Expect = 1e-16
Identities = 81/329 (24%), Positives = 139/329 (41%), Gaps = 59/329 (17%)
Query: 541 IVLDQTAFYPEGGGQPYDTGVLFVNGSE---------------VKVTNVQKVGKVIVHKV 585
+VL + +PEGGGQP D G L V + + +TNV++VG + +
Sbjct: 110 VVLSDSVLFPEGGGQPCDHGTLRVVSGDNDKADPSCDATAAPPLSITNVRRVGDTCI--L 167
Query: 586 ENPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQAGSQLTTDWA-- 643
+P G V +DW RR+ HM+HHTG H+L + R + LT +
Sbjct: 168 TSPAALPVGATVHQMVDWPRRMDHMQHHTGQHLLTAVVERKDTLRLPTVSWSLTHPYCFI 227
Query: 644 RLDISHY---------------KRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQR 688
++D+ Y K+ISDE + +IE L N + V + E R
Sbjct: 228 QVDVGGYASDPASPYHAYITKEKKISDEMVAKIEALCNDAIAHSTTVQCDVFENREVYMR 287
Query: 689 YGFRLYQ-------GGV-------VPGRV---IRVVKIEDWDVQACGGTHLPSTGLVGPI 731
R +Q GG +P V IR++ ++ D C GTHL + + +
Sbjct: 288 EQDRRHQAAAVSADGGAEAFRSRGIPEDVTGPIRIISLDAIDSCTCCGTHLHTLAELQAM 347
Query: 732 KILRTERIQDGVERIIFACGEAAIKE----WQKEREILKKASQVLRVPPEKLPETAERFF 787
+L E ++ + ++ F GE A ++ +Q+ER+++ + P+ +R
Sbjct: 348 YLLHQE-VKGTLVKLYFITGERAAQQFHAMYQRERQLMPELG---GSRPDDFVSVVQRRS 403
Query: 788 NEWKEARKEVEKLKKELAKLLVYELEAKV 816
+ + K +++ ELA + + A V
Sbjct: 404 KDATDLEKLMKRWTLELASVEAQRIAAAV 432
>gb|AAF50804.1| (AE003567) Aats-ala-m gene product [Drosophila melanogaster]
Length = 1012
Score = 88.5 bits (216), Expect = 3e-16
Identities = 112/501 (22%), Positives = 211/501 (41%), Gaps = 90/501 (17%)
Query: 341 IADHTKALTFMLADGVIPSNVKAGYLARLLIRKSIRHLKEL-GLEVPLSEIVALHIKELH 399
+ADH + +T LADG++P + R ++RK++ + + + L+++V + ++ L
Sbjct: 306 LADHARMVTACLADGMLPDQNQK---LRRVLRKALNISEHVFAHDKLLTQLVPIVVETLG 362
Query: 400 KTFPEFKEMEDVILEIIDLEEKKYSETLKRGS----------------DLVR-------- 435
+ +PE + ++++I E++ Y + S DL+
Sbjct: 363 EAYPEMAAKQQAVIDLICHEQEVYKNLRESSSKAFAEVLMEFPNLDDIDLMECPGFVPAY 422
Query: 436 REIAKLKKK-GMSEIPLEKLITFYESHGLTPELVKEIAEKEGI-----KVHVPDNFYSIV 489
RE+ + K + IP + L +++GLT E ++AE E + + + +
Sbjct: 423 RELQMQRCKFSNNTIPGDFLYKLTDTYGLTEESFLKLAELENMNCDLERYRAEVSLAKLK 482
Query: 490 AKEAEKEKE-------EKEEEVVDFE--LVKDLPETRTLY-YEDPFMKEFEARVL----- 534
AK ++E E+ + + + L K L T + Y F KE ++ +
Sbjct: 483 AKGNQRETAGGSLCDLATEQRIAEAQAMLTKRLTPTDNSHKYTYSFDKESDSYQIPPLKT 542
Query: 535 RVIGDW-----------------------IVLDQTAFYPEGGGQPYDTGVLFVNGSE--- 568
RV+G IV + FY E GGQ D G + V+ +
Sbjct: 543 RVLGMLLNDAEVSRTQGSRIQQPFTDLISIVTAGSNFYYESGGQQSDGGKILVSNHQQPD 602
Query: 569 ----VKVTNVQKVGKVIVH--KVENPG---LFKEGMEVRGRIDWDRRIQHMRHHTGTHVL 619
+ V V+ + +VH K+ +P G EV ++D +R + HHT TH+L
Sbjct: 603 HPHSLDVIGVKHLNDCVVHICKLSSPTDAFQLAIGDEVELQVDAQQRQLNTCHHTATHLL 662
Query: 620 MGALVRVLGKHVWQAGSQLTTDWARLDISHY-KRISDEELREIERLANRIVMEDRKVTWE 678
A+ + K +Q S +++D +L++ KRI +++ IE L NR++ V +
Sbjct: 663 NAAIRSLFKKVTYQVSSSVSSDQCKLELGLLGKRIQKTDVQLIEDLINRVICSAAPVEVQ 722
Query: 679 WLPRTEAEQRYGFRLYQGGVVPGRVIRVVKIEDWDVQ-----ACGGTHLPSTGLVGPIKI 733
L E ++ + G V P + +R+V +E ++Q C GTH +T + I
Sbjct: 723 LLSAAEVLEQNDITMVPGEVYPEQGLRLVNVESPELQLSSKELCCGTHATNTSELSCFCI 782
Query: 734 LRTERIQDGVERIIFACGEAA 754
+ ++ G+AA
Sbjct: 783 VNLKQTNRARFAFTAVAGQAA 803
>pir||T03808 alanine--tRNA ligase (EC 6.1.1.7) - Mycoplasma hyopneumoniae
(fragment) >gi|2654772|gb|AAC32529.1| (AF012905)
alanyl-tRNA synthase [Mycoplasma hyopneumoniae]
Length = 186
Score = 78.4 bits (190), Expect = 3e-13
Identities = 52/181 (28%), Positives = 91/181 (49%), Gaps = 38/181 (20%)
Query: 55 KKYTLDEMREKFLKFFEKHEVYPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWVISGEAD 114
+K + +E+R+ ++ FF + H ++ P++P+ D +L + + + + + +G+
Sbjct: 2 EKLSANEIRQLWIDFFREKN---HFFIESKPLVPQNDDSLLWINSGVATLKDY-FTGKKI 57
Query: 115 PPANPLVISQPSIRFTDIDNVGITGRHFTIFEMMAHHAFNYPGKPIYWIDETVELAFEFF 174
PP+ LV SQ ++R DI+NVG+T RH T+FEM+ + + Y+ E ++ A+EF
Sbjct: 58 PPSKRLVNSQKALRTNDIENVGLTSRHHTLFEMLGNFSIG-----DYFKTEAIDYAYEFL 112
Query: 175 TKELKMKP----------EDITF------------------KENPW-AGGGNAGPAFEVL 205
TK+LK+ P +DITF K N W G G GP E+
Sbjct: 113 TKKLKLDPKNLFITYYDGDDITFEKWKSLGFSNEKLIKGSKKTNFWDLGQGPCGPCSEIY 172
Query: 206 Y 206
+
Sbjct: 173 F 173
>gb|AAK41508.1| Alanyl-tRNA synthetase truncated homolog (alaS-like2) [Sulfolobus
solfataricus]
Length = 150
Score = 78.0 bits (189), Expect = 4e-13
Identities = 42/124 (33%), Positives = 69/124 (54%), Gaps = 3/124 (2%)
Query: 610 MRHHTGTHVLMGALVRVLGKHVWQAGSQLTTDWARLDISHYKRISDEELREIERLANRIV 669
+R HT HV+ GA+ +VLG W A + + ++ RL + ++ SD+E+ ++ LAN V
Sbjct: 6 IRTHTALHVVKGAVRKVLGAK-WTASTYVNSNHGRLTVKFERKPSDQEMDKVFELANEKV 64
Query: 670 MEDRKVTWEWLPRTEAEQRYGFRLYQGGVVPGRV--IRVVKIEDWDVQACGGTHLPSTGL 727
++ + E LPR EAE++YG +Y ++ V + +V I DW + AC H T
Sbjct: 65 RKNLPIIIEVLPREEAERKYGDEIYDLFLISAEVRELSIVVIPDWSINACNKQHTKFTSE 124
Query: 728 VGPI 731
+G I
Sbjct: 125 IGEI 128
>emb|CAC11640.1| (AL445064) conserved hypothetical protein [Thermoplasma
acidophilum]
Length = 237
Score = 72.2 bits (174), Expect = 2e-11
Identities = 59/228 (25%), Positives = 105/228 (45%), Gaps = 11/228 (4%)
Query: 515 ETRTLYYEDPFMKEFEARVLRVIGDWIVLDQTAFYPEGGGQPYDTGVLFVNGSEVKVTNV 574
+T+ LY +D + E + V + +DQ+ FYP G+P DTG + ++G E ++ +
Sbjct: 2 KTKALYLDDSYATEGTGTAIFVEFTDMKVDQSIFYPTTFGEPNDTGKVIIDGKEYQIVDT 61
Query: 575 QKVGKVI-VHKVENPGLFKEGMEVRGRIDWDRRIQHMRHHTGTHVLMGALVRVLGKHVWQ 633
G+ I + ++ G V+ +IDWD+R HMR T ++ G L W+
Sbjct: 62 IYDGEYIHLISMDTYPQTVVGKTVKQKIDWDKRYIHMRFRTALRIISG-----LAYAKWK 116
Query: 634 AGSQLT---TDWARLDISHYKRISDEELREIERLANRIVMEDRKVTWEWLPRTEAEQRYG 690
++ D A +DI I+++E+ EI AN +V +D V + ++ + +
Sbjct: 117 VSCRVNETYDDRAWIDIEK-PDITEDEINEIMAEANDVVKKDLDVRFRYIGLEDFNRSED 175
Query: 691 F-RLYQGGVVPGRVIRVVKIEDWDVQACGGTHLPSTGLVGPIKILRTE 737
++ IR++ IE Q G ++ TG VG I T+
Sbjct: 176 LKKMSIHDAYDEDRIRIMSIEGLPDQPEFGVNVKKTGEVGQINYKTTK 223
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.319 0.139 0.409
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 357908597
Number of Sequences: 2977
Number of extensions: 16432625
Number of successful extensions: 63869
Number of sequences better than 1.0e-10: 92
Number of HSP's better than 0.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 67
Number of HSP's that attempted gapping in prelim test: 63270
Number of HSP's gapped (non-prelim): 207
length of query: 914
length of database: 189,106,746
effective HSP length: 57
effective length of query: 857
effective length of database: 154,992,987
effective search space: 132828989859
effective search space used: 132828989859
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 169 (70.2 bits)